# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- 5_nucleotid_C PF02872.18 GAN00579.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain bZIP_1 PF00170.21 GAN00580.1 - 1.2e-09 38.1 12.9 2.6e-09 37.1 12.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN00580.1 - 1.6e-05 24.9 13.2 1.6e-05 24.9 13.2 2.6 3 0 0 3 3 3 1 Basic region leucine zipper Kinesin_assoc PF16183.5 GAN00580.1 - 0.063 13.4 1.6 0.13 12.4 0.0 2.1 1 1 1 2 2 2 0 Kinesin-associated bZIP_Maf PF03131.17 GAN00580.1 - 5.9 7.5 13.6 0.33 11.5 7.2 2.1 1 1 0 2 2 2 0 bZIP Maf transcription factor Forkhead PF00250.18 GAN00581.1 - 0.014 15.7 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 Forkhead domain IL10 PF00726.17 GAN00581.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Interleukin 10 Nop14 PF04147.12 GAN00582.1 - 8.4e-288 957.3 51.2 9.8e-288 957.1 51.2 1.0 1 0 0 1 1 1 1 Nop14-like family Bac_surface_Ag PF01103.23 GAN00583.1 - 6.6e-48 163.9 0.0 8.3e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Ribosomal_L19 PF01245.20 GAN00583.1 - 0.16 12.0 0.8 0.57 10.1 0.3 2.0 1 1 1 2 2 2 0 Ribosomal protein L19 E1-E2_ATPase PF00122.20 GAN00584.1 - 8e-20 71.1 0.0 1.5e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAN00584.1 - 4.3e-16 59.8 0.0 4.5e-09 36.9 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN00584.1 - 0.014 15.1 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Med1 PF10744.9 GAN00585.1 - 8.3e-39 133.8 1.0 8.3e-39 133.8 1.0 1.7 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 UBX PF00789.20 GAN00585.1 - 0.075 13.2 1.2 0.32 11.2 0.1 2.5 2 0 0 2 2 2 0 UBX domain CLZ PF16526.5 GAN00585.1 - 1.1 9.7 4.5 3.4 8.1 1.4 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Abhydrolase_3 PF07859.13 GAN00586.1 - 2.1e-32 112.7 0.1 1.7e-21 77.1 0.0 3.5 3 1 1 4 4 4 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN00586.1 - 0.0035 16.2 0.0 0.0068 15.3 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyoxalase_4 PF13669.6 GAN00586.1 - 0.051 13.9 0.0 0.45 10.8 0.0 2.4 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-MYND PF01753.18 GAN00588.1 - 2.6e-05 24.2 15.4 2.6e-05 24.2 15.4 2.1 2 0 0 2 2 2 1 MYND finger SET PF00856.28 GAN00588.1 - 0.00069 20.0 0.0 0.0022 18.4 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-C6H2 PF15801.5 GAN00588.1 - 1.1 9.7 14.4 2.5 8.5 14.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3094 PF11293.8 GAN00589.1 - 0.058 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Tetraspanin PF00335.20 GAN00589.1 - 0.15 11.7 24.5 0.86 9.3 16.0 2.2 1 1 1 2 2 2 0 Tetraspanin family Cyt_c_ox_IV PF12270.8 GAN00589.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV FA_desaturase PF00487.24 GAN00589.1 - 0.84 9.4 6.2 0.42 10.4 3.5 1.9 2 0 0 2 2 2 0 Fatty acid desaturase OAD_gamma PF04277.13 GAN00589.1 - 0.96 10.1 0.1 0.96 10.1 0.1 2.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain ArAE_2_N PF10337.9 GAN00589.1 - 1.2 8.1 10.6 1.6 7.7 0.3 2.1 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal SRTM1 PF15872.5 GAN00589.1 - 1.3 9.2 7.3 1.1 9.4 3.0 2.4 2 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 MARVEL PF01284.23 GAN00589.1 - 2.8 8.0 27.1 12 5.9 25.3 2.0 1 1 0 1 1 1 0 Membrane-associating domain DUF4231 PF14015.6 GAN00589.1 - 3 8.4 7.8 1 9.9 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) FPV060 PF17614.2 GAN00590.1 - 0.01 15.2 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 0 Viral CC-type chemokine ELFV_dehydrog PF00208.21 GAN00591.1 - 2.3e-58 197.8 0.0 3.7e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAN00591.1 - 1.4e-24 85.8 0.1 8.4e-18 63.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase PX PF00787.24 GAN00592.1 - 9.9e-24 83.5 2.0 2.7e-23 82.1 2.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 GAN00592.1 - 1.8e-06 27.7 12.7 0.00018 21.1 3.4 2.4 2 0 0 2 2 2 2 Vps5 C terminal like Sec8_exocyst PF04048.14 GAN00592.1 - 3.6 7.5 9.3 2.1 8.3 1.4 2.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1825 PF08855.10 GAN00592.1 - 4.8 7.2 9.6 2.3 8.2 2.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1825) Alpha_E1_glycop PF01589.16 GAN00594.1 - 0.44 9.1 8.4 0.42 9.2 7.5 1.3 1 1 0 1 1 1 0 Alphavirus E1 glycoprotein Patched PF02460.18 GAN00595.1 - 1.8e-83 281.1 18.0 8.4e-49 166.4 1.0 2.7 2 1 0 3 3 3 2 Patched family NPC1_N PF16414.5 GAN00595.1 - 1.5e-78 263.7 7.2 2.3e-78 263.1 7.2 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 GAN00595.1 - 1.7e-48 164.3 6.2 1.7e-48 164.3 6.2 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 GAN00595.1 - 7.3e-05 21.8 4.1 7.3e-05 21.8 4.1 2.7 3 0 0 3 3 3 1 MMPL family Folate_rec PF03024.14 GAN00595.1 - 0.0051 16.7 8.7 0.044 13.6 2.2 2.4 2 0 0 2 2 2 2 Folate receptor family ACR_tran PF00873.19 GAN00595.1 - 0.23 9.1 23.8 0.0057 14.4 17.0 1.6 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Pkinase PF00069.25 GAN00596.1 - 3.8e-52 177.3 0.1 7e-52 176.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00596.1 - 5.1e-24 85.0 0.1 1.1e-23 83.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAN00596.1 - 0.0025 16.8 0.1 0.0041 16.2 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 GAN00596.1 - 0.0078 15.8 0.7 0.51 9.9 0.0 2.6 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 GAN00596.1 - 0.11 11.8 0.4 1.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Kinase-like NTP_transf_2 PF01909.23 GAN00597.1 - 6.4e-07 29.6 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 GAN00597.1 - 7.9e-07 29.2 0.0 2.6e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 GAN00597.1 - 0.0056 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase IL31 PF15209.6 GAN00597.1 - 0.085 12.6 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Interleukin 31 PHD PF00628.29 GAN00598.1 - 2.5e-05 24.1 11.5 6.8e-05 22.7 11.5 1.8 1 0 0 1 1 1 1 PHD-finger GATA PF00320.27 GAN00598.1 - 7.7e-05 22.2 5.3 0.00014 21.3 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-PHD-like PF15446.6 GAN00598.1 - 0.0068 16.0 6.3 0.0068 16.0 6.3 2.1 2 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain MAJIN PF15077.6 GAN00598.1 - 1.1 9.0 6.3 1.7 8.4 6.3 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4442 PF14539.6 GAN00599.1 - 1.6e-09 38.0 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Ribosomal_L34e PF01199.18 GAN00600.1 - 1.8e-45 153.2 6.1 2.2e-45 152.9 6.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e NUC153 PF08159.12 GAN00601.1 - 1.3e-17 63.3 9.8 2.3e-14 52.9 0.5 3.9 3 0 0 3 3 3 3 NUC153 domain EZH2_WD-Binding PF11616.8 GAN00601.1 - 2.1 8.5 4.8 1.9 8.6 1.9 2.3 2 0 0 2 2 2 0 WD repeat binding protein EZH2 ER PF01133.17 GAN00602.1 - 3.9e-21 74.9 0.0 4.9e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Enhancer of rudimentary AP_endonuc_2 PF01261.24 GAN00602.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel RRM_1 PF00076.22 GAN00603.1 - 2.3e-42 142.7 0.1 2.6e-22 78.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAN00603.1 - 0.00058 20.0 0.1 2.1 8.6 0.0 2.9 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 GAN00603.1 - 0.026 14.6 0.0 19 5.4 0.0 3.7 3 1 0 3 3 3 0 RNA recognition motif Plk4_PB1 PF18190.1 GAN00603.1 - 0.2 11.8 3.7 0.91 9.7 0.0 2.8 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 1 Lipase_3 PF01764.25 GAN00604.1 - 6.9e-18 64.9 0.0 1.3e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Robl_LC7 PF03259.17 GAN00604.1 - 0.098 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain Utp21 PF04192.12 GAN00605.1 - 4e-71 239.2 1.0 6.1e-71 238.6 1.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 GAN00605.1 - 1.4e-29 101.7 19.8 1.1e-07 32.4 0.5 10.3 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN00605.1 - 2.2e-21 76.0 3.3 4.2e-06 27.0 0.0 7.7 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN00605.1 - 8.5e-10 37.9 12.0 0.0051 15.5 0.7 5.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAN00605.1 - 5.6e-05 22.1 1.9 0.019 13.7 0.1 3.0 2 1 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.6 GAN00605.1 - 9.1e-05 22.1 0.0 0.22 11.1 0.0 2.9 2 1 1 3 3 3 2 PQQ-like domain WD40_like PF17005.5 GAN00605.1 - 0.00011 21.6 2.7 0.46 9.8 0.0 3.6 3 1 0 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 GAN00605.1 - 0.03 12.8 0.6 0.74 8.3 0.0 3.0 4 0 0 4 4 4 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 GAN00605.1 - 0.073 12.0 7.4 1.4 7.8 0.0 4.5 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TCO89 PF10452.9 GAN00606.1 - 8.3e-07 28.4 19.5 1.6e-06 27.4 19.2 1.5 1 1 0 1 1 1 1 TORC1 subunit TCO89 BRE1 PF08647.11 GAN00606.1 - 0.088 12.9 6.9 0.097 12.8 5.8 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 GAN00606.1 - 0.57 8.7 15.5 0.75 8.3 15.5 1.2 1 0 0 1 1 1 0 Macoilin family VanZ PF04892.12 GAN00607.1 - 3.9e-10 40.5 2.4 5.1e-10 40.1 2.4 1.1 1 0 0 1 1 1 1 VanZ like family PrsW-protease PF13367.6 GAN00607.1 - 0.069 12.6 0.7 0.1 12.0 0.7 1.3 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease TMCCDC2 PF15844.5 GAN00607.1 - 0.09 12.7 0.8 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 RA PF00788.23 GAN00608.1 - 2.5e-10 40.8 0.0 2.7e-05 24.7 0.0 3.0 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 GAN00608.1 - 2.1e-05 24.0 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN00608.1 - 0.0098 15.7 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ufm1 PF03671.14 GAN00608.1 - 0.025 14.6 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein TRA-1_regulated PF02343.16 GAN00608.1 - 8.9 6.4 6.0 2.5 8.2 0.2 3.1 3 0 0 3 3 3 0 TRA-1 regulated protein R03H10.4 RSN1_7TM PF02714.15 GAN00609.1 - 5.8e-77 258.7 28.9 5.8e-77 258.7 28.9 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAN00609.1 - 2.4e-35 122.4 0.0 4.5e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAN00609.1 - 1.2e-32 112.8 4.7 1.2e-32 112.8 4.7 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport CBM_14 PF01607.24 GAN00610.1 - 5.6e-10 39.2 4.4 1.5e-09 37.9 4.5 1.6 1 1 1 2 2 2 1 Chitin binding Peritrophin-A domain DUF4449 PF14613.6 GAN00612.1 - 5.4e-12 46.1 1.2 5.4e-12 46.1 1.2 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 GAN00612.1 - 0.0038 16.8 0.2 0.0086 15.7 0.2 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain DUF2294 PF10057.9 GAN00612.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2294) DUF1040 PF06288.13 GAN00612.1 - 0.32 11.4 1.7 23 5.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) DUF3837 PF12939.7 GAN00612.1 - 9.2 6.7 6.5 23 5.5 0.9 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) DUF974 PF06159.13 GAN00613.1 - 1.3e-77 261.0 0.2 2.4e-77 260.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.7 GAN00613.1 - 5.4e-10 39.2 1.0 5.6e-05 22.7 0.0 3.9 3 1 1 4 4 4 3 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 GAN00613.1 - 1.3e-05 25.3 0.1 0.00067 19.8 0.0 2.5 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain ACBP PF00887.19 GAN00614.1 - 1.8e-25 88.9 0.0 5.7e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4611 PF15387.6 GAN00614.1 - 0.015 15.5 0.8 0.015 15.5 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AATF-Che1 PF13339.6 GAN00614.1 - 0.21 12.3 6.1 0.36 11.5 0.1 3.1 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor ADH_zinc_N PF00107.26 GAN00615.1 - 2.7e-34 117.9 0.1 4.3e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN00615.1 - 3.2e-12 47.6 0.0 6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN00615.1 - 7.6e-08 32.2 0.0 1.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 GAN00615.1 - 0.0042 17.3 0.4 0.0078 16.5 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.21 GAN00615.1 - 0.0048 16.2 1.0 0.0076 15.6 1.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 GAN00615.1 - 0.15 12.0 0.0 0.66 9.9 0.0 2.0 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase HSF_DNA-bind PF00447.17 GAN00616.1 - 3e-32 111.1 2.4 3e-32 111.1 2.4 2.2 2 1 0 2 2 2 1 HSF-type DNA-binding RAMP PF04901.13 GAN00616.1 - 0.043 13.8 3.4 2.1 8.4 0.4 2.5 2 0 0 2 2 2 0 Receptor activity modifying family Ribosomal_L24e PF01246.20 GAN00617.1 - 8.1e-14 51.6 0.7 1.2e-13 51.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e MMU163 PF17119.5 GAN00617.1 - 0.27 10.3 3.0 0.38 9.9 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Ribosomal_S4e PF00900.20 GAN00618.1 - 8.4e-38 128.1 1.1 1.9e-36 123.8 0.4 2.3 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 GAN00618.1 - 1.1e-25 89.0 0.2 3.5e-25 87.4 0.1 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 GAN00618.1 - 3.5e-19 68.6 7.4 1.2e-18 67.0 7.9 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 GAN00618.1 - 4.2e-07 29.6 0.0 8.7e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 GAN00618.1 - 0.00014 21.7 8.4 0.00057 19.7 6.5 3.0 3 1 0 3 3 3 1 KOW motif Pkinase PF00069.25 GAN00619.1 - 4.9e-60 203.1 0.0 7.8e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00619.1 - 7.4e-46 156.5 0.0 5e-45 153.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN00619.1 - 9.1e-07 28.0 2.4 9.8e-07 27.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN00619.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YabA PF06156.13 GAN00619.1 - 0.56 10.9 2.3 1.5 9.5 2.3 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Pkinase PF00069.25 GAN00621.1 - 2.3e-45 155.0 0.0 1.8e-44 152.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00621.1 - 5.4e-23 81.6 0.0 8.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN00621.1 - 0.00095 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN00621.1 - 0.023 14.6 0.0 1.5 8.7 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN00621.1 - 0.28 9.9 0.0 0.28 9.9 0.0 2.4 2 1 1 3 3 3 0 Fungal protein kinase Pkinase PF00069.25 GAN00622.1 - 1.1e-53 182.3 0.4 2.7e-53 181.0 0.4 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00622.1 - 7.9e-23 81.1 0.0 1.3e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GAN00622.1 - 0.0055 16.3 0.4 0.015 14.9 0.4 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAN00622.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAN00622.1 - 0.11 12.1 1.6 0.18 11.3 0.5 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase TPR_2 PF07719.17 GAN00623.1 - 5e-23 79.3 4.5 0.0026 17.7 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAN00623.1 - 6.8e-21 73.2 6.5 3.6e-05 23.4 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat DnaJ PF00226.31 GAN00623.1 - 2.2e-20 72.5 4.1 2.2e-20 72.5 4.1 3.0 2 1 1 3 3 3 1 DnaJ domain TPR_16 PF13432.6 GAN00623.1 - 9.1e-14 51.8 0.8 9.6e-07 29.4 0.1 4.4 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAN00623.1 - 1.3e-13 51.2 13.0 0.0048 17.4 2.2 5.9 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAN00623.1 - 1.7e-13 49.6 6.5 0.0017 18.4 0.0 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN00623.1 - 2.9e-12 46.5 6.6 0.011 15.9 0.6 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN00623.1 - 1.4e-10 41.1 8.6 0.009 16.8 0.1 6.6 4 3 4 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN00623.1 - 2.1e-08 34.0 6.8 0.00017 21.7 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN00623.1 - 3.3e-08 33.1 7.4 9.6e-05 22.0 0.7 5.4 5 2 2 7 7 7 3 TPR repeat ANAPC3 PF12895.7 GAN00623.1 - 3.9e-07 30.2 9.1 0.32 11.2 0.8 4.6 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAN00623.1 - 3e-05 24.2 8.6 0.26 11.6 0.1 5.4 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAN00623.1 - 3.3e-05 24.2 12.3 0.065 13.9 0.0 7.3 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN00623.1 - 0.00049 19.9 6.6 7.1 6.9 0.0 5.8 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAN00623.1 - 0.0026 18.0 15.3 0.084 13.2 0.0 5.2 3 2 1 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.17 GAN00623.1 - 0.0027 18.2 3.0 1.2 9.5 0.0 3.3 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 GAN00623.1 - 0.0037 17.3 5.1 0.2 11.8 0.1 4.5 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat PknG_TPR PF16918.5 GAN00623.1 - 0.017 13.8 0.7 1.3 7.6 0.0 3.1 3 1 0 3 3 3 0 Protein kinase G tetratricopeptide repeat SesA PF17107.5 GAN00623.1 - 0.029 14.6 1.2 4.2 7.6 0.1 3.1 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_10 PF13374.6 GAN00623.1 - 0.045 13.6 3.3 0.88 9.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ACP53EA PF06313.11 GAN00623.1 - 0.076 13.2 0.5 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Drosophila ACP53EA protein DUF357 PF04010.13 GAN00623.1 - 0.34 11.0 2.3 40 4.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF357) OHCU_decarbox PF09349.10 GAN00623.1 - 0.57 10.7 6.9 0.92 10.0 0.3 2.9 2 1 1 3 3 3 0 OHCU decarboxylase BLOC1_2 PF10046.9 GAN00623.1 - 5.2 7.4 10.6 0.43 10.9 1.6 3.5 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ion_trans PF00520.31 GAN00624.1 - 1.7e-23 83.2 26.4 2.3e-23 82.7 26.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 GAN00624.1 - 3.6e-10 39.7 11.1 3.6e-10 39.7 11.1 2.8 2 1 1 3 3 3 1 Ion channel DUF4643 PF15485.6 GAN00624.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) HAD_SAK_1 PF10307.9 GAN00625.1 - 4.1e-61 206.3 0.0 5.9e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins COX17 PF05051.13 GAN00627.1 - 5e-22 78.0 5.1 5.9e-22 77.8 5.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cwf_Cwc_15 PF04889.12 GAN00628.1 - 0.049 13.3 5.2 0.06 13.1 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L32p PF01783.23 GAN00629.1 - 7.5e-15 54.9 6.6 1.1e-14 54.4 6.6 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 GAN00629.1 - 0.04 13.9 1.2 0.061 13.3 1.2 1.3 1 0 0 1 1 1 0 zinc-ribbons zinc_ribbon_2 PF13240.6 GAN00629.1 - 0.18 11.6 3.1 0.54 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAN00629.1 - 0.48 10.6 2.5 0.47 10.6 0.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain IF-2B PF01008.17 GAN00630.1 - 7.7e-80 268.1 0.0 1e-79 267.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Mitofilin PF09731.9 GAN00630.1 - 0.0047 15.8 9.8 0.0061 15.5 9.8 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein HPS6 PF15702.5 GAN00630.1 - 0.044 11.8 0.0 0.069 11.1 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein GFO_IDH_MocA PF01408.22 GAN00631.1 - 3.2e-26 92.5 0.2 5.8e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 GAN00631.1 - 8.4e-09 35.9 0.0 1.7e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAN00631.1 - 1.4e-05 25.2 0.1 3.2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 GAN00631.1 - 1.5e-05 25.6 0.0 3.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 GAN00631.1 - 0.00054 20.4 0.0 0.0014 19.1 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAN00631.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PMT PF02366.18 GAN00632.1 - 2e-72 243.7 14.0 4e-72 242.8 14.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAN00632.1 - 1.4e-63 214.2 7.6 1.4e-63 214.2 7.6 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAN00632.1 - 1.2e-38 132.8 2.1 2.5e-38 131.8 2.1 1.5 1 0 0 1 1 1 1 MIR domain Frizzled PF01534.17 GAN00633.1 - 7.8e-09 35.0 16.3 1.4e-08 34.2 16.3 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 GAN00633.1 - 1.5e-05 25.5 6.2 3.7e-05 24.3 6.2 1.7 1 1 0 1 1 1 1 Fz domain Dicty_CAR PF05462.11 GAN00633.1 - 0.00077 18.7 6.5 0.0014 17.8 6.5 1.6 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Strabismus PF06638.11 GAN00633.1 - 0.055 12.1 1.0 0.11 11.1 1.0 1.4 1 0 0 1 1 1 0 Strabismus protein PGG PF13962.6 GAN00633.1 - 0.14 12.0 5.4 0.12 12.2 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function PspB PF06667.12 GAN00633.1 - 1.6 8.9 3.5 3.9 7.6 0.5 2.9 3 0 0 3 3 3 0 Phage shock protein B Amidohydro_2 PF04909.14 GAN00636.1 - 0.074 12.8 0.1 0.077 12.8 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase Gln-synt_C PF00120.24 GAN00637.1 - 6.4e-24 84.6 0.0 5.9e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GAN00637.1 - 6.4e-12 45.0 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PIG-P PF08510.12 GAN00638.1 - 1.6e-40 137.7 9.0 3.4e-40 136.7 9.0 1.6 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 GAN00638.1 - 0.039 14.3 9.6 0.072 13.4 9.6 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DNA_Packaging_2 PF11123.8 GAN00638.1 - 0.062 13.5 0.2 0.29 11.4 0.1 2.1 1 1 1 2 2 2 0 DNA packaging protein VAD1-2 PF15310.6 GAN00638.1 - 2.8 7.7 12.0 0.19 11.6 5.2 2.3 2 1 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling Lactamase_B PF00753.27 GAN00641.1 - 8.3e-18 65.1 1.3 2.6e-17 63.5 1.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN00641.1 - 3.3e-05 23.5 0.1 9.3e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 GAN00641.1 - 0.0032 17.4 0.1 0.0088 16.0 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_6 PF16661.5 GAN00641.1 - 0.098 12.1 0.1 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain LIAS_N PF16881.5 GAN00642.1 - 3.4e-22 78.9 0.5 7.1e-22 77.9 0.5 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 GAN00642.1 - 3.4e-11 43.8 0.4 5.6e-11 43.1 0.1 1.5 2 0 0 2 2 2 1 Radical SAM superfamily MGTL PF17059.5 GAN00643.1 - 0.032 14.0 2.3 0.17 11.7 2.3 2.2 1 0 0 1 1 1 0 MgtA leader peptide Microtub_bd PF16796.5 GAN00645.1 - 0.001 19.0 0.1 0.0034 17.3 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding Syntaxin_2 PF14523.6 GAN00645.1 - 0.0034 17.7 6.3 0.0034 17.7 6.3 4.4 5 0 0 5 5 5 2 Syntaxin-like protein Fusion_gly PF00523.18 GAN00645.1 - 0.13 10.5 3.4 0.63 8.2 0.7 2.5 2 0 0 2 2 2 0 Fusion glycoprotein F0 Clr2 PF10383.9 GAN00645.1 - 1.3 9.8 6.1 11 6.8 0.6 3.0 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 Myb_DNA-binding PF00249.31 GAN00646.1 - 0.0012 18.9 0.1 0.0044 17.2 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain BUD22 PF09073.10 GAN00646.1 - 0.43 9.9 25.1 0.035 13.5 20.2 1.7 2 0 0 2 2 2 0 BUD22 Macoilin PF09726.9 GAN00646.1 - 1.7 7.1 14.7 3.2 6.2 14.7 1.4 1 0 0 1 1 1 0 Macoilin family Sec23_trunk PF04811.15 GAN00647.1 - 1.7e-58 198.1 0.0 7.2e-58 196.0 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAN00647.1 - 5.7e-18 65.4 0.0 1.5e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GAN00647.1 - 9.1e-18 64.0 0.0 2.5e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GAN00647.1 - 1.1e-15 57.3 1.9 3e-15 56.0 1.9 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAN00647.1 - 9.4e-09 35.1 0.0 9.4e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAN00647.1 - 0.004 16.5 0.1 0.0092 15.4 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain MRNIP PF15749.5 GAN00647.1 - 1.8 9.4 7.4 0.44 11.3 0.9 2.3 2 0 0 2 2 2 0 MRN-interacting protein Not1 PF04054.15 GAN00649.1 - 1.3e-143 478.4 2.8 4e-143 476.8 2.8 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAN00649.1 - 8.9e-99 329.4 11.7 8.7e-98 326.2 6.5 3.1 3 0 0 3 3 3 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 GAN00649.1 - 3.6e-70 235.0 1.1 9.9e-70 233.6 0.2 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 GAN00649.1 - 9.4e-50 168.3 9.3 9.4e-50 168.3 9.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 GAN00649.1 - 2.3e-23 82.9 2.3 1e-22 80.8 2.3 2.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat SUIM_assoc PF16619.5 GAN00649.1 - 1.8 8.7 5.3 12 6.1 1.7 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Fungal_trans PF04082.18 GAN00650.1 - 1.9e-24 86.2 0.0 1.9e-24 86.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN00650.1 - 9.7e-11 41.6 12.7 1.9e-10 40.7 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 GAN00650.1 - 0.0075 16.3 18.0 0.0075 16.3 18.0 3.1 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 GAN00650.1 - 6.2 6.7 19.6 0.66 9.9 6.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) F-box-like PF12937.7 GAN00651.1 - 2.1e-08 33.9 1.3 3.4e-08 33.2 0.4 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN00651.1 - 6.5e-05 22.7 0.1 0.00021 21.1 0.1 1.9 1 0 0 1 1 1 1 F-box domain Cse1 PF08506.10 GAN00652.1 - 1.9e-151 504.1 9.2 3.1e-151 503.4 9.2 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 GAN00652.1 - 1.8e-124 415.6 0.3 1.8e-124 415.6 0.3 1.5 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus WD40 PF00400.32 GAN00652.1 - 2.4e-26 91.4 15.8 1.4e-05 25.7 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat IBN_N PF03810.19 GAN00652.1 - 1e-15 57.4 0.2 5.6e-15 55.0 0.2 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain ANAPC4_WD40 PF12894.7 GAN00652.1 - 4.9e-14 52.4 0.1 1.6e-05 25.1 0.1 4.5 4 1 1 5 5 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN00652.1 - 1.5e-05 25.0 0.3 0.032 14.1 0.1 4.0 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN00652.1 - 0.00091 18.3 3.4 0.13 11.2 0.0 3.8 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 GAN00652.1 - 0.0012 18.6 0.3 0.0035 17.1 0.3 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 GAN00652.1 - 0.032 14.2 1.4 1.1 9.3 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Xpo1 PF08389.12 GAN00652.1 - 0.044 13.8 5.2 0.089 12.9 0.0 4.0 4 1 1 5 5 5 0 Exportin 1-like protein DUF3385 PF11865.8 GAN00652.1 - 0.064 13.2 2.0 0.99 9.3 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) HD_assoc PF13286.6 GAN00652.1 - 0.12 13.0 0.8 29 5.3 0.1 2.8 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Arm PF00514.23 GAN00652.1 - 0.4 10.8 1.7 3.9 7.6 0.0 3.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CAP_GLY PF01302.25 GAN00653.1 - 1.8e-19 69.5 0.2 2.7e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Dehydrin PF00257.19 GAN00653.1 - 0.077 13.5 1.1 0.077 13.5 1.1 1.8 2 0 0 2 2 2 0 Dehydrin LSM PF01423.22 GAN00654.1 - 1.2e-17 63.3 0.2 1.5e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAN00654.1 - 0.022 14.9 0.0 0.029 14.5 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Iso_dh PF00180.20 GAN00656.1 - 2.5e-81 273.5 0.0 3e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ART-PolyVal PF18760.1 GAN00656.1 - 0.024 15.7 0.1 0.056 14.5 0.1 1.6 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins GTP_EFTU PF00009.27 GAN00657.1 - 6.2e-45 153.1 0.0 1.3e-44 152.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAN00657.1 - 1.6e-36 125.0 2.0 6.4e-36 123.1 0.3 2.7 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAN00657.1 - 1.9e-11 44.2 0.4 4.3e-11 43.0 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAN00657.1 - 0.0031 17.6 0.2 0.035 14.2 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Peptidase_U32_C PF16325.5 GAN00657.1 - 0.012 15.9 0.2 0.036 14.3 0.2 1.8 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain LPD34 PF18852.1 GAN00657.1 - 0.051 13.2 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 FAP PF07174.11 GAN00657.1 - 0.2 11.1 31.5 0.31 10.5 31.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SH3_1 PF00018.28 GAN00658.1 - 2.4e-27 94.3 0.0 2.3e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 GAN00658.1 - 8.5e-17 60.8 0.0 5.9e-08 32.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 GAN00658.1 - 3e-15 55.6 0.0 4.1e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 GAN00658.1 - 4.8e-09 36.2 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 GAN00658.1 - 1.6e-05 24.8 0.1 4e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 PB1 domain Pex14_N PF04695.13 GAN00659.1 - 4 8.1 17.6 2.8 8.6 0.3 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_Gly3P_dh_C PF07479.14 GAN00660.1 - 5.6e-50 169.3 0.1 9.2e-50 168.6 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 GAN00660.1 - 1.7e-49 167.8 0.0 3.2e-49 166.9 0.0 1.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 GAN00660.1 - 0.018 15.6 0.1 0.23 12.1 0.1 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ras PF00071.22 GAN00661.1 - 5.3e-60 201.7 0.6 6.4e-60 201.4 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN00661.1 - 3.8e-34 117.5 0.2 5.9e-34 116.9 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN00661.1 - 2.1e-13 50.1 0.1 2.9e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN00661.1 - 3.1e-07 30.5 0.1 4.9e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN00661.1 - 2.1e-05 24.1 0.2 0.00021 20.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN00661.1 - 0.00035 20.5 0.2 0.35 10.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAN00661.1 - 0.002 17.5 0.2 0.0029 17.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAN00661.1 - 0.0051 16.3 0.1 0.0091 15.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 GAN00661.1 - 0.07 13.4 0.1 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 GAN00661.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein SLAC1 PF03595.17 GAN00662.1 - 8.9e-86 288.1 52.1 1e-85 287.9 52.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel KDZ PF18758.1 GAN00663.1 - 3.3e-44 151.1 0.2 5.9e-44 150.3 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase ZapB PF06005.12 GAN00663.1 - 0.034 14.6 1.6 2.3 8.7 0.2 3.0 2 0 0 2 2 2 0 Cell division protein ZapB BLI1 PF17324.2 GAN00663.1 - 0.079 13.6 0.7 0.26 12.0 0.7 1.9 1 0 0 1 1 1 0 BLOC-1 interactor 1 CTU2 PF10288.9 GAN00665.1 - 1.5e-20 73.5 1.3 1.5e-20 73.5 1.3 2.3 3 0 0 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 GAN00665.1 - 0.00017 21.4 0.1 0.26 11.0 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Chitin_synth_2 PF03142.15 GAN00666.1 - 9.1e-234 776.9 3.1 1.4e-233 776.3 3.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAN00666.1 - 1.3e-114 383.9 5.4 2.3e-112 376.4 5.4 2.9 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 GAN00666.1 - 4.3e-18 65.0 0.1 1.8e-17 63.0 0.2 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 GAN00666.1 - 7e-14 52.2 4.4 7e-14 52.2 4.4 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAN00666.1 - 4e-13 49.8 0.0 1.7e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 GAN00666.1 - 2.8e-11 43.4 0.2 3e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 GAN00666.1 - 0.0051 16.6 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN00666.1 - 0.0082 15.6 0.3 0.09 12.3 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 21 T2SSE PF00437.20 GAN00666.1 - 0.14 11.2 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RabGAP-TBC PF00566.18 GAN00667.1 - 4.3e-45 154.0 0.7 1.4e-44 152.4 0.7 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps5 PF09325.10 GAN00668.1 - 4.8e-14 52.5 6.7 4.8e-14 52.5 6.7 2.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 GAN00668.1 - 3.2e-10 40.0 0.3 3.2e-10 40.0 0.3 2.2 2 1 0 2 2 2 1 PX domain FAM92 PF06730.11 GAN00668.1 - 0.0056 16.1 2.0 0.0056 16.1 2.0 2.0 2 0 0 2 2 2 1 FAM92 protein DUF1993 PF09351.10 GAN00668.1 - 0.0068 16.6 0.4 0.022 14.9 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) LMBR1 PF04791.16 GAN00668.1 - 0.026 13.5 5.2 0.036 13.0 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BAR PF03114.18 GAN00668.1 - 0.58 9.8 16.8 0.022 14.4 9.5 2.2 2 1 0 2 2 2 0 BAR domain T2SSM PF04612.12 GAN00668.1 - 1 9.4 3.7 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Hexokinase_2 PF03727.16 GAN00669.1 - 1.5e-75 253.7 0.0 3.9e-75 252.4 0.0 1.7 1 0 0 1 1 1 1 Hexokinase Oxysterol_BP PF01237.18 GAN00669.1 - 1.5e-65 221.5 8.7 9.6e-64 215.5 8.7 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Hexokinase_1 PF00349.21 GAN00669.1 - 3.3e-54 183.8 0.0 5.4e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF1160 PF06648.11 GAN00669.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) VPS9 PF02204.18 GAN00670.1 - 4.9e-19 68.5 0.0 1.9e-18 66.6 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAN00670.1 - 8.8e-14 51.6 0.2 8.8e-14 51.6 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 GAN00670.1 - 0.00062 19.4 0.1 0.0022 17.6 0.0 2.1 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 GAN00670.1 - 0.047 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif ACBP PF00887.19 GAN00671.1 - 2.8e-29 101.1 0.8 3.1e-29 101.0 0.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_M24 PF00557.24 GAN00672.1 - 3.5e-56 190.2 0.0 4.6e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAN00672.1 - 2.3e-39 133.9 0.0 3.9e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dus PF01207.17 GAN00673.1 - 1.6e-58 198.2 0.0 2.5e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Orthopox_F7 PF05813.12 GAN00673.1 - 0.056 13.6 0.1 0.26 11.4 0.1 2.2 1 0 0 1 1 1 0 Orthopoxvirus F7 protein zf-CCCH_4 PF18044.1 GAN00673.1 - 0.097 12.5 9.3 0.077 12.8 2.4 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger Peptidase_S8 PF00082.22 GAN00674.1 - 3e-44 151.5 0.0 9.4e-44 149.8 0.0 1.8 1 1 1 2 2 2 1 Subtilase family fn3_5 PF06280.12 GAN00674.1 - 8.7e-12 45.7 2.0 1.9e-11 44.7 2.0 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 GAN00674.1 - 2.5e-11 43.4 0.1 2.5e-11 43.4 0.1 2.0 2 0 0 2 2 2 1 PA domain DUF916 PF06030.12 GAN00674.1 - 0.019 15.0 0.4 0.052 13.6 0.4 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) EHN PF06441.12 GAN00675.1 - 7.5e-30 103.5 2.3 1.8e-29 102.3 2.3 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAN00675.1 - 1.4e-13 51.0 0.0 3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN00675.1 - 1.7e-07 32.1 0.0 7.4e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family WH2 PF02205.20 GAN00675.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 WH2 motif AMO PF02461.16 GAN00675.1 - 0.11 12.2 0.1 0.99 9.1 0.1 2.1 2 0 0 2 2 2 0 Ammonia monooxygenase His_Phos_2 PF00328.22 GAN00676.1 - 1.9e-25 90.0 0.0 2.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) E3_binding PF02817.17 GAN00676.1 - 0.035 14.5 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 e3 binding domain Ras PF00071.22 GAN00677.1 - 1.7e-57 193.6 0.0 2e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN00677.1 - 2.1e-32 111.9 0.0 4.1e-32 110.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN00677.1 - 4.8e-14 52.2 0.1 6.5e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN00677.1 - 9.4e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN00677.1 - 0.00037 20.1 0.3 0.049 13.2 0.1 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN00677.1 - 0.0013 18.7 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase KAP_NTPase PF07693.14 GAN00677.1 - 0.023 14.0 0.0 0.027 13.7 0.0 1.0 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 GAN00677.1 - 0.057 13.8 0.1 0.1 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 GAN00677.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 GAN00677.1 - 0.065 12.5 0.1 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 GAN00677.1 - 0.1 12.9 0.1 0.21 11.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain EphA2_TM PF14575.6 GAN00678.1 - 7.5 7.5 8.4 36 5.3 0.1 4.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EMP24_GP25L PF01105.24 GAN00679.1 - 3.5e-40 137.9 0.7 8.6e-40 136.6 0.7 1.7 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DNA_pol3_gamma3 PF12169.8 GAN00679.1 - 0.055 13.4 1.0 0.16 11.9 0.4 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III ATP-synt_C PF00137.21 GAN00681.1 - 7.6e-32 109.4 33.2 1.5e-18 66.9 12.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C MBOAT PF03062.19 GAN00682.1 - 8.5e-37 127.3 19.0 3.2e-36 125.4 18.7 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NAP PF00956.18 GAN00683.1 - 2e-98 328.9 11.9 2e-98 328.9 11.9 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Afaf PF15339.6 GAN00683.1 - 0.064 13.0 0.4 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 Acrosome formation-associated factor Cwf_Cwc_15 PF04889.12 GAN00683.1 - 0.066 12.9 34.3 0.028 14.2 16.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 GAN00683.1 - 0.17 12.1 41.3 0.94 9.7 22.4 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 GAN00683.1 - 0.2 9.8 36.4 0.15 10.2 8.2 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 GAN00683.1 - 1.3 8.3 30.6 0.34 10.2 4.1 2.1 2 0 0 2 2 2 0 BUD22 TFIIA PF03153.13 GAN00683.1 - 3.8 7.4 23.1 1.5 8.7 2.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 GAN00683.1 - 4.5 6.6 33.1 0.3 10.5 6.0 2.2 2 0 0 2 2 2 0 SDA1 Astro_capsid_p PF12226.8 GAN00683.1 - 8.9 5.4 32.4 7.3 5.6 9.0 2.2 2 0 0 2 2 2 0 Turkey astrovirus capsid protein ECH_1 PF00378.20 GAN00684.1 - 1.4e-41 142.5 0.0 1.8e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN00684.1 - 3.7e-11 43.1 0.0 5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UQ_con PF00179.26 GAN00685.1 - 1.2e-44 151.3 0.0 3.2e-44 150.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN00685.1 - 0.085 13.1 0.1 0.085 13.1 0.1 3.0 2 1 0 2 2 2 0 RWD domain MFS_1 PF07690.16 GAN00688.1 - 1.8e-36 125.8 68.9 2.4e-27 95.8 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN00688.1 - 0.0014 17.3 27.5 0.017 13.7 11.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 GAN00688.1 - 0.0029 16.6 13.4 0.0029 16.6 13.4 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter Arm PF00514.23 GAN00689.1 - 1.5e-33 113.8 25.7 6.1e-07 29.3 0.5 11.6 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAN00689.1 - 8.1e-17 59.9 20.5 0.071 13.4 0.0 9.5 10 0 0 10 10 8 5 HEAT repeat HEAT_2 PF13646.6 GAN00689.1 - 4.8e-14 52.5 13.5 0.015 15.6 0.2 7.6 4 4 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 GAN00689.1 - 1.8e-09 37.9 21.0 0.19 12.3 0.1 9.0 9 1 0 9 9 9 4 HEAT-like repeat Cnd1 PF12717.7 GAN00689.1 - 2.1e-08 34.4 7.5 0.00023 21.2 0.6 4.1 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 GAN00689.1 - 1.9e-06 27.9 8.0 0.12 12.4 0.0 5.4 4 2 2 6 6 6 3 Domain of unknown function (DUF3361) Vac14_Fab1_bd PF12755.7 GAN00689.1 - 2.7e-05 24.7 3.1 0.68 10.6 0.1 4.4 4 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 GAN00689.1 - 0.0022 18.0 1.7 3.4 7.8 0.0 4.7 5 0 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 GAN00689.1 - 0.015 14.8 1.8 0.66 9.5 0.0 3.1 3 1 0 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 GAN00689.1 - 0.05 13.8 6.1 1.8 8.8 0.0 5.2 5 2 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 GAN00689.1 - 5.5 7.4 11.2 16 6.0 0.1 5.2 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Peptidase_M28 PF04389.17 GAN00690.1 - 4.8e-30 104.7 0.0 9.4e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Rap_GAP PF02145.15 GAN00690.1 - 9.2e-28 97.1 0.0 3e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 Rap/ran-GAP DUF2730 PF10805.8 GAN00691.1 - 0.0046 17.0 0.6 0.015 15.4 0.1 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF2730) Tantalus PF15386.6 GAN00691.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 Drosophila Tantalus-like DUF267 PF03268.14 GAN00691.1 - 0.021 13.7 0.2 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 LapA_dom PF06305.11 GAN00691.1 - 0.054 13.3 0.4 0.13 12.0 0.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UDPGP PF01704.18 GAN00691.1 - 0.068 11.8 0.5 0.079 11.6 0.5 1.1 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase DUF5408 PF17402.2 GAN00691.1 - 0.068 13.1 0.7 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5408) Ycf54 PF10674.9 GAN00691.1 - 0.14 12.4 0.2 0.29 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) YebO PF13974.6 GAN00691.1 - 0.42 10.7 4.0 0.79 9.9 4.0 1.6 1 1 0 1 1 1 0 YebO-like protein DUF3552 PF12072.8 GAN00691.1 - 0.61 9.5 8.4 0.47 9.9 7.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) FTHFS PF01268.19 GAN00692.1 - 1.5e-262 871.7 0.7 1.7e-262 871.6 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 GAN00692.1 - 1.5e-67 225.9 1.6 1.5e-67 225.9 1.6 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAN00692.1 - 1.7e-39 134.7 1.5 2.5e-38 130.9 1.6 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 GAN00692.1 - 0.027 14.5 2.5 0.54 10.3 1.1 2.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IF2_N PF04760.15 GAN00692.1 - 0.05 13.4 0.0 6.4 6.7 0.0 2.9 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region AA_permease_2 PF13520.6 GAN00693.1 - 4.1e-55 187.3 55.3 5e-55 187.0 55.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN00693.1 - 2.5e-38 131.9 48.0 3.3e-38 131.5 48.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAN00693.1 - 2e-05 24.6 6.4 2e-05 24.6 6.4 3.8 3 0 0 3 3 3 1 C-terminus of AA_permease Nucleoside_tran PF01733.18 GAN00695.1 - 2.6e-54 184.7 12.9 2.6e-54 184.7 12.9 2.0 2 1 0 2 2 2 1 Nucleoside transporter UCR_TM PF02921.14 GAN00695.1 - 0.13 12.7 0.2 0.59 10.6 0.1 2.2 1 1 1 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region MnhB PF04039.13 GAN00695.1 - 0.44 10.9 0.1 0.44 10.9 0.1 4.0 4 1 1 5 5 5 0 Domain related to MnhB subunit of Na+/H+ antiporter 5_nucleotid PF05761.14 GAN00697.1 - 1.3e-117 393.5 4.3 2.1e-115 386.3 0.6 3.1 3 1 1 4 4 4 2 5' nucleotidase family Drc1-Sld2 PF11719.8 GAN00697.1 - 1.8e-12 47.6 3.7 1.8e-12 47.6 3.7 2.9 2 1 0 2 2 2 1 DNA replication and checkpoint protein TFIIA PF03153.13 GAN00697.1 - 3.4 7.5 20.4 7 6.5 20.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.21 GAN00698.1 - 4.7e-28 98.4 0.0 5.3e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAN00698.1 - 7e-09 35.0 0.0 1.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase RRF PF01765.19 GAN00698.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Abhydrolase_1 PF00561.20 GAN00699.1 - 2.2e-09 37.3 0.0 6.2e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN00699.1 - 5.6e-06 25.8 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 GAN00699.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lactamase_B_2 PF12706.7 GAN00700.1 - 3.3e-05 23.5 0.1 0.00013 21.6 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 GAN00700.1 - 0.0017 18.5 0.4 0.014 15.5 0.4 2.5 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 GAN00700.1 - 0.08 12.9 0.8 0.57 10.2 0.8 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PSP1 PF04468.12 GAN00701.1 - 1.1e-33 115.3 4.4 1.1e-33 115.3 4.4 3.1 3 1 0 3 3 3 1 PSP1 C-terminal conserved region MMR_HSR1 PF01926.23 GAN00702.1 - 5.1e-16 58.8 3.1 4.7e-15 55.7 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN00702.1 - 1e-07 32.0 0.9 0.00016 21.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAN00702.1 - 4.2e-07 29.6 0.1 8.6e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Sporozoite_P67 PF05642.11 GAN00702.1 - 0.00019 19.7 0.8 0.00023 19.5 0.8 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AIG1 PF04548.16 GAN00702.1 - 0.00022 20.6 0.1 0.00022 20.6 0.1 2.3 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 GAN00702.1 - 0.042 13.9 0.1 0.042 13.9 0.1 3.9 4 0 0 4 4 4 0 Dynamin family CDC45 PF02724.14 GAN00702.1 - 0.054 11.8 8.2 0.084 11.2 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GAN00702.1 - 0.2 10.4 8.5 0.31 9.8 8.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GAN00702.1 - 3.5 6.3 5.3 6.4 5.4 5.3 1.3 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 GAN00702.1 - 9.6 6.3 9.4 22 5.1 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ank_2 PF12796.7 GAN00703.1 - 2e-15 57.1 1.9 2.9e-09 37.4 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN00703.1 - 1.7e-13 50.8 2.9 1.2e-09 38.5 0.2 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN00703.1 - 1.5e-09 37.3 3.3 0.0003 21.0 0.2 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 GAN00703.1 - 1.4e-08 34.8 12.1 3.8e-06 27.1 0.3 5.0 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAN00703.1 - 2.3e-06 27.8 2.0 0.054 13.8 0.2 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 GAN00703.1 - 0.0018 18.1 0.1 0.023 14.5 0.1 2.6 1 1 0 1 1 1 1 KilA-N domain FdhD-NarQ PF02634.15 GAN00703.1 - 0.025 14.3 0.2 0.049 13.3 0.2 1.5 1 0 0 1 1 1 0 FdhD/NarQ family Filament PF00038.21 GAN00703.1 - 0.24 11.0 19.7 0.46 10.0 11.1 2.2 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.11 GAN00703.1 - 3.5 8.1 7.3 11 6.5 0.6 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Nup54 PF13874.6 GAN00703.1 - 4.3 7.4 12.8 18 5.4 12.6 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Fez1 PF06818.15 GAN00703.1 - 5.4 7.4 24.0 0.46 10.9 17.4 2.1 2 0 0 2 2 2 0 Fez1 DUF5320 PF17253.2 GAN00703.1 - 5.9 8.0 7.0 36 5.5 0.8 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) AAA_13 PF13166.6 GAN00703.1 - 9.1 4.8 15.0 19 3.7 15.0 1.4 1 0 0 1 1 1 0 AAA domain DAO PF01266.24 GAN00704.1 - 2e-53 182.3 0.1 2.6e-53 181.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN00704.1 - 3e-05 24.2 0.3 0.00012 22.2 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAN00704.1 - 0.0014 17.9 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 GAN00704.1 - 0.0057 16.0 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAN00704.1 - 0.016 14.5 1.7 0.078 12.2 1.7 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN00704.1 - 0.026 14.5 0.3 0.055 13.5 0.3 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAN00704.1 - 0.029 13.6 0.4 0.43 9.8 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 GAN00704.1 - 0.032 12.8 0.0 0.27 9.7 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 GAN00704.1 - 0.063 12.4 0.7 0.11 11.6 0.2 1.6 2 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 GAN00704.1 - 0.15 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding EMP24_GP25L PF01105.24 GAN00705.1 - 2e-44 151.7 0.2 2.8e-44 151.2 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EF-hand_7 PF13499.6 GAN00705.1 - 2.4e-12 47.1 0.1 7.3e-08 32.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAN00705.1 - 6.9e-11 40.9 0.1 3.9e-05 22.9 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAN00705.1 - 9.5e-11 40.7 0.2 3.5e-05 23.4 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAN00705.1 - 0.00095 18.6 1.0 0.0035 16.8 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 GAN00705.1 - 0.0032 17.3 0.3 0.014 15.3 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 GAN00705.1 - 0.04 14.2 0.0 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Hydrolase_6 PF13344.6 GAN00706.1 - 2.8e-30 104.4 0.0 1.5e-29 102.1 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN00706.1 - 1.5e-19 69.8 0.0 5.8e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAN00706.1 - 2.1e-16 60.9 0.2 7.9e-16 59.0 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN00706.1 - 3.7e-10 40.2 0.0 2.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN00706.1 - 0.03 14.1 0.0 11 5.7 0.0 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF853 PF05872.12 GAN00706.1 - 0.18 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RRM_1 PF00076.22 GAN00707.1 - 7.6e-23 80.1 0.0 3.2e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 GAN00707.1 - 9e-23 78.6 5.3 7.9e-06 25.3 0.0 7.0 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat DUF4523 PF15023.6 GAN00707.1 - 3.6e-06 26.9 0.2 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_8 PF11835.8 GAN00707.1 - 0.00093 19.4 0.2 0.0053 16.9 0.0 2.3 3 0 0 3 3 3 1 RRM-like domain Nab6_mRNP_bdg PF10567.9 GAN00707.1 - 0.0014 18.2 0.0 0.056 12.9 0.0 2.5 2 0 0 2 2 2 1 RNA-recognition motif RRM_occluded PF16842.5 GAN00707.1 - 0.0041 16.9 0.0 0.67 9.9 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4378 PF14309.6 GAN00707.1 - 0.04 14.3 0.8 2 8.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4378) RRM_3 PF08777.11 GAN00707.1 - 0.13 12.4 0.0 21 5.2 0.0 3.1 2 0 0 2 2 2 0 RNA binding motif Spt20 PF12090.8 GAN00707.1 - 0.4 10.3 13.5 2.6 7.6 5.8 2.5 2 0 0 2 2 2 0 Spt20 family PAT1 PF09770.9 GAN00707.1 - 1.5 7.0 8.4 1.2 7.3 0.0 3.0 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Pinin_SDK_memA PF04696.13 GAN00708.1 - 8.8e-28 97.0 23.7 8.8e-28 97.0 23.7 2.4 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 GAN00708.1 - 4.2e-05 23.8 12.3 4.2e-05 23.8 12.3 3.1 2 1 0 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Pkinase PF00069.25 GAN00709.1 - 2.1e-48 165.0 0.0 2.1e-48 165.0 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00709.1 - 8.5e-16 58.0 2.0 3.1e-15 56.2 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase ABC1 PF03109.16 GAN00709.1 - 0.062 13.5 0.2 0.76 10.0 0.0 2.5 2 0 0 2 2 2 0 ABC1 family RED_N PF07808.13 GAN00710.1 - 1.4e-37 129.5 23.4 1.4e-37 129.5 23.4 3.2 2 2 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 GAN00710.1 - 1.8e-21 76.7 8.6 1.8e-21 76.7 8.6 2.7 3 0 0 3 3 3 1 RED-like protein C-terminal region ANAPC4_WD40 PF12894.7 GAN00710.1 - 6.2e-08 32.8 3.2 1.5e-05 25.2 0.1 4.7 1 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN00710.1 - 0.023 15.5 11.1 1 10.3 0.0 5.3 6 1 0 6 6 6 0 WD domain, G-beta repeat HrpF PF06266.12 GAN00711.1 - 0.35 11.2 1.3 10 6.5 0.1 3.0 3 0 0 3 3 3 0 HrpF protein RhoGEF PF00621.20 GAN00712.1 - 2.1e-28 99.8 0.6 5.2e-28 98.5 0.4 1.7 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 GAN00712.1 - 3.3e-05 24.4 0.0 8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Serglycin PF04360.12 GAN00713.1 - 0.0092 15.9 0.9 0.01 15.8 0.9 1.2 1 0 0 1 1 1 1 Serglycin Rtt106 PF08512.12 GAN00714.1 - 1.2e-29 102.6 0.1 5.5e-29 100.4 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 GAN00714.1 - 6.9e-27 93.7 0.1 2.8e-23 82.1 0.0 2.6 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 GAN00714.1 - 2.1e-23 82.0 0.0 7.1e-23 80.3 0.0 2.0 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) MRF_C1 PF13887.6 GAN00714.1 - 0.019 14.1 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 DUF2057 PF09829.9 GAN00714.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) CDC37_M PF08565.11 GAN00714.1 - 0.099 12.6 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain EPL1 PF10513.9 GAN00715.1 - 5.3e-14 52.9 1.0 5.3e-14 52.9 1.0 2.9 3 1 0 3 3 3 1 Enhancer of polycomb-like TFIIA PF03153.13 GAN00715.1 - 8.4 6.3 18.5 14 5.5 18.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_18 PF00704.28 GAN00716.1 - 1.9e-24 86.9 9.1 8e-24 84.9 9.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 GAN00716.1 - 8.7e-09 35.2 8.8 8.7e-09 35.2 8.8 3.9 3 1 1 4 4 4 1 Carbohydrate binding domain (family 19) SOG2 PF10428.9 GAN00716.1 - 8.7 5.4 35.3 14 4.7 35.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Arrestin_N PF00339.29 GAN00717.1 - 1.3e-17 64.2 0.1 2.5e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN00717.1 - 8.7e-06 25.6 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Rgp1 PF08737.10 GAN00717.1 - 0.00068 18.9 0.2 0.0016 17.7 0.2 1.5 1 0 0 1 1 1 1 Rgp1 muHD PF10291.9 GAN00718.1 - 4.9e-27 95.0 0.2 9.2e-27 94.1 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 GAN00718.1 - 1.9e-11 44.1 0.5 8.7e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PAP_assoc PF03828.19 GAN00719.1 - 2e-10 40.7 0.3 5.5e-10 39.3 0.3 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase UAA PF08449.11 GAN00720.1 - 2.1e-97 326.0 15.3 2.7e-97 325.6 15.3 1.1 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 GAN00720.1 - 0.00013 21.1 1.2 0.00013 21.1 1.2 2.2 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAN00720.1 - 0.074 13.2 28.1 5.6 7.1 10.8 3.5 2 2 0 2 2 2 0 EamA-like transporter family 2OG-FeII_Oxy_2 PF13532.6 GAN00721.1 - 9.4e-14 52.0 0.0 3e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EF-1_beta_acid PF10587.9 GAN00721.1 - 0.012 16.0 1.0 0.028 14.9 1.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF768 PF05589.11 GAN00721.1 - 0.038 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF768) MamL-1 PF09596.10 GAN00723.1 - 0.083 13.2 1.5 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 MamL-1 domain Hydrolase_like PF13242.6 GAN00724.1 - 1.6e-10 40.8 0.0 3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 GAN00724.1 - 1.5e-08 34.6 0.0 3.5e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN00724.1 - 0.034 14.2 0.1 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAN00724.1 - 0.092 12.4 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Cyclin PF08613.11 GAN00725.1 - 2e-35 122.6 0.1 2e-35 122.6 0.1 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAN00725.1 - 8.7e-08 32.0 0.1 1.5e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PBP1_TM PF14812.6 GAN00725.1 - 1.1 9.6 7.8 2 8.9 7.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GAN00725.1 - 5.1 6.3 8.8 7.3 5.8 8.8 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GAN00725.1 - 6.8 6.4 6.7 12 5.6 6.7 1.4 1 0 0 1 1 1 0 FAM176 family zf-Tim10_DDP PF02953.15 GAN00726.1 - 2.7e-18 65.3 0.5 3.3e-18 65.1 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 GAN00726.1 - 0.027 14.2 1.1 0.19 11.5 1.1 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Kei1 PF08552.11 GAN00727.1 - 0.99 9.3 8.9 6 6.7 8.9 1.9 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 E1-E2_ATPase PF00122.20 GAN00727.1 - 8.5 5.9 5.6 10 5.6 4.4 1.7 2 0 0 2 2 2 0 E1-E2 ATPase Xan_ur_permease PF00860.20 GAN00728.1 - 7.6e-26 90.7 30.5 1.7e-24 86.3 28.4 2.8 2 1 0 2 2 2 1 Permease family FHA PF00498.26 GAN00731.1 - 4.3e-14 52.6 0.1 1.3e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 FHA domain G-patch PF01585.23 GAN00731.1 - 2.4e-11 43.4 2.2 4.5e-11 42.5 2.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN00731.1 - 1.8e-07 31.2 0.0 5.2e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 GAN00731.1 - 1.5e-05 24.9 5.2 0.0025 17.8 3.4 2.7 2 0 0 2 2 2 2 OCRE domain Yop-YscD_cpl PF16697.5 GAN00731.1 - 3.9e-05 23.9 0.0 9.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ima1_N PF09779.9 GAN00731.1 - 0.5 11.2 3.6 0.22 12.4 0.7 1.9 2 0 0 2 2 2 0 Ima1 N-terminal domain PQ-loop PF04193.14 GAN00732.1 - 1.6e-26 91.8 10.2 3.7e-14 52.2 2.7 2.9 2 1 1 3 3 3 2 PQ loop repeat Peptidase_U4 PF03419.13 GAN00732.1 - 0.091 12.0 9.9 0.19 11.0 9.9 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF3021 PF11457.8 GAN00732.1 - 2.3 8.6 16.1 0.19 12.1 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) DUF4044 PF13253.6 GAN00732.1 - 4.3 6.9 6.1 12 5.5 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Ribosomal_S8e PF01201.22 GAN00733.1 - 3.4e-55 186.0 0.7 3.9e-55 185.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Abhydrolase_1 PF00561.20 GAN00734.1 - 2.5e-20 73.2 0.3 4.8e-16 59.2 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 GAN00734.1 - 2.1e-16 59.3 0.4 5.4e-16 57.9 0.4 1.7 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 GAN00734.1 - 0.00017 20.9 0.0 0.012 14.9 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Laterosporulin PF17861.1 GAN00734.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Laterosporulin defensin-like peptide Bap31 PF05529.12 GAN00735.1 - 2.9e-45 153.4 1.6 4.3e-45 152.9 1.6 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 GAN00735.1 - 1.4e-09 37.8 15.9 1.5e-08 34.5 15.9 2.2 1 1 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2065 PF09838.9 GAN00735.1 - 0.05 13.6 1.7 0.11 12.5 1.7 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) PHR PF08005.12 GAN00735.1 - 0.087 13.5 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 PHR domain DUF2987 PF11205.8 GAN00735.1 - 0.13 12.1 2.8 0.21 11.5 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) Jnk-SapK_ap_N PF09744.9 GAN00735.1 - 0.22 11.7 15.3 0.2 11.9 12.9 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FAM76 PF16046.5 GAN00735.1 - 3.1 7.1 7.8 2.7 7.3 5.6 1.7 1 1 1 2 2 2 0 FAM76 protein ZapB PF06005.12 GAN00735.1 - 7.4 7.1 16.4 0.55 10.7 7.7 2.5 2 1 1 3 3 3 0 Cell division protein ZapB Ycf70 PF17382.2 GAN00735.1 - 7.8 7.0 8.6 17 5.9 0.1 3.5 1 1 3 4 4 4 0 Uncharacterized Ycf70-like HSP20 PF00011.21 GAN00736.1 - 1.2e-18 67.1 0.2 3.2e-12 46.5 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAN00736.1 - 1.6e-07 30.8 0.0 0.0094 15.5 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA tRNA_synt_1c_R2 PF04557.15 GAN00736.1 - 0.0018 19.1 1.8 0.23 12.4 0.5 2.3 2 0 0 2 2 2 2 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Galactosyl_T PF01762.21 GAN00737.1 - 2.6e-21 76.3 0.0 4.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 GAN00737.1 - 8.6e-15 55.1 6.0 1.7e-14 54.1 6.0 1.5 1 0 0 1 1 1 1 N-glycosylation protein Gly_transf_sug PF04488.15 GAN00737.1 - 6.9e-09 36.2 0.5 2.5e-08 34.4 0.3 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 GAN00737.1 - 9.3e-06 25.8 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Caps_synth PF05704.12 GAN00737.1 - 0.00042 19.8 0.4 0.00097 18.6 0.4 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 GAN00737.1 - 0.082 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Cys_Met_Meta_PP PF01053.20 GAN00738.1 - 4.4e-136 453.4 0.0 5e-136 453.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAN00738.1 - 1.5e-06 27.5 0.0 2.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAN00738.1 - 2.2e-05 23.8 0.0 3.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 GAN00738.1 - 0.012 14.6 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.21 GAN00738.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase RICTOR_N PF14664.6 GAN00739.1 - 3.1e-101 339.1 1.5 1.3e-100 337.0 1.5 2.0 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 GAN00739.1 - 3.1e-38 130.5 0.2 2.5e-37 127.6 0.1 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 GAN00739.1 - 9.3e-38 128.2 1.3 5.4e-34 116.1 0.1 5.0 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 GAN00739.1 - 2.2e-31 107.9 2.4 1.7e-28 98.6 0.1 4.6 5 1 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 GAN00739.1 - 6.4e-07 29.4 2.7 1.8e-06 27.9 2.7 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.6 GAN00739.1 - 1.2e-05 25.6 1.9 0.97 9.9 0.1 5.3 6 1 0 6 6 5 2 HEAT repeats Adaptin_N PF01602.20 GAN00739.1 - 0.00017 20.3 4.1 0.42 9.1 0.0 3.6 3 1 0 3 3 3 2 Adaptin N terminal region CREPT PF16566.5 GAN00739.1 - 0.0018 18.5 1.8 0.0052 17.0 1.8 1.8 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour HEAT PF02985.22 GAN00739.1 - 0.024 14.9 1.2 71 4.1 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.23 GAN00739.1 - 0.045 13.8 10.0 3 8.0 0.0 5.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DHR10 PF18595.1 GAN00739.1 - 0.26 11.4 4.0 0.65 10.1 4.0 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF5344 PF17279.2 GAN00739.1 - 0.61 10.7 4.0 1.2 9.8 1.7 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5344) DUF962 PF06127.11 GAN00740.1 - 5.9e-22 77.6 0.9 1.3e-21 76.4 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Peptidase_S9 PF00326.21 GAN00741.1 - 2.5e-06 27.1 0.1 4.9e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 GAN00741.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.9 GAN00741.1 - 0.014 14.5 0.1 0.025 13.7 0.1 1.4 1 0 0 1 1 1 0 Abhydrolase domain containing 18 PhoPQ_related PF10142.9 GAN00741.1 - 0.048 12.3 0.3 0.083 11.5 0.1 1.5 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.13 GAN00741.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 GAN00741.1 - 0.085 12.4 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GSHPx PF00255.19 GAN00742.1 - 3.4e-39 132.8 0.1 4.4e-39 132.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GAN00742.1 - 4.9e-06 26.5 0.1 3e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAN00742.1 - 0.0045 16.7 0.1 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 Redoxin FAD-oxidase_C PF02913.19 GAN00743.1 - 1.8e-63 214.5 0.0 2.8e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAN00743.1 - 6.5e-37 126.4 0.0 1.8e-36 124.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Androgen_recep PF02166.16 GAN00743.1 - 0.38 9.5 3.4 0.6 8.9 3.4 1.3 1 0 0 1 1 1 0 Androgen receptor BTB PF00651.31 GAN00744.1 - 2.1e-15 56.9 0.5 2.2e-09 37.5 0.2 2.7 2 0 0 2 2 2 2 BTB/POZ domain CAP_GLY PF01302.25 GAN00744.1 - 9.8e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain E1-E2_ATPase PF00122.20 GAN00745.1 - 1.7e-26 92.9 0.4 7.8e-26 90.7 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAN00745.1 - 6.4e-12 46.2 0.0 3.1e-06 27.6 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN00745.1 - 1.7e-05 24.4 0.2 9e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAN00745.1 - 0.014 15.5 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAN00745.1 - 0.28 10.9 3.3 0.42 10.3 0.1 2.6 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase PQ-loop PF04193.14 GAN00746.1 - 9.8e-20 70.1 14.9 1.8e-12 46.8 2.3 3.3 4 0 0 4 4 4 2 PQ loop repeat DUF2530 PF10745.9 GAN00746.1 - 0.19 12.0 6.7 0.17 12.2 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) MtN3_slv PF03083.16 GAN00746.1 - 2.1 8.4 13.9 1 9.4 1.3 2.9 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange WCOR413 PF05562.11 GAN00746.1 - 2.2 8.2 10.0 0.52 10.2 3.4 2.8 1 1 2 3 3 3 0 Cold acclimation protein WCOR413 Smg8_Smg9 PF10220.9 GAN00747.1 - 1.6e-82 278.3 9.3 2.6e-42 145.2 3.6 5.0 4 1 0 4 4 4 4 Smg8_Smg9 GET2 PF08690.10 GAN00748.1 - 1.8 8.2 7.7 0.31 10.7 3.2 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 Mitochondr_Som1 PF11093.8 GAN00749.1 - 2e-11 43.7 0.2 2.6e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 HGTP_anticodon PF03129.20 GAN00750.1 - 1.6e-22 79.5 0.0 2.6e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAN00750.1 - 3.6e-07 30.3 0.1 8.9e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) MYEOV2 PF15004.6 GAN00751.1 - 4.4e-08 33.5 2.2 1.2e-07 32.0 2.2 1.9 1 0 0 1 1 1 1 Myeloma-overexpressed-like LAT PF15234.6 GAN00751.1 - 0.041 13.6 5.6 0.049 13.4 5.6 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells DNA_pol_phi PF04931.13 GAN00751.1 - 2 6.4 5.8 1.6 6.7 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi ESCRT-II PF05871.12 GAN00752.1 - 3.1e-41 140.9 2.6 4.4e-41 140.4 2.6 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Sin3a_C PF16879.5 GAN00753.1 - 5e-58 197.1 10.6 5e-58 197.1 10.6 3.6 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein Creatinase_N_2 PF16189.5 GAN00753.1 - 2e-52 177.6 0.8 1.1e-51 175.1 0.0 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GAN00753.1 - 1e-42 146.2 0.0 2.1e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 PAH PF02671.21 GAN00753.1 - 9.4e-40 134.5 10.9 6.5e-17 61.4 2.9 4.3 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAN00753.1 - 1.3e-39 134.2 0.1 5.3e-39 132.2 0.1 2.2 1 0 0 1 1 1 1 Sin3 family co-repressor Peptidase_M24_C PF16188.5 GAN00753.1 - 7.7e-22 77.1 0.0 4.7e-21 74.6 0.0 2.5 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAN00753.1 - 1.9e-19 70.6 0.3 4.3e-16 59.8 0.0 3.4 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain DUF4030 PF13222.6 GAN00753.1 - 0.097 12.8 2.5 0.24 11.6 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) FANCI_S3 PF14677.6 GAN00753.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.4 3 0 0 3 3 3 0 FANCI solenoid 3 DUF2408 PF10303.9 GAN00753.1 - 5.3 7.6 9.9 1.3 9.6 0.0 4.4 3 2 1 4 4 4 0 Protein of unknown function (DUF2408) CENP-W PF15510.6 GAN00754.1 - 0.0015 18.7 0.0 0.0018 18.4 0.0 1.4 1 1 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 GAN00754.1 - 0.18 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Membralin PF09746.9 GAN00756.1 - 0.1 11.6 2.2 0.15 11.0 2.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein HTH_45 PF14947.6 GAN00756.1 - 0.12 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix NOA36 PF06524.12 GAN00756.1 - 0.18 11.1 9.8 0.27 10.5 9.8 1.1 1 0 0 1 1 1 0 NOA36 protein Pox_A12 PF04651.13 GAN00756.1 - 0.19 11.8 8.7 0.31 11.1 8.7 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein PPP4R2 PF09184.11 GAN00756.1 - 0.21 11.1 13.8 0.3 10.6 13.8 1.1 1 0 0 1 1 1 0 PPP4R2 NTP_transf_6 PF06042.11 GAN00756.1 - 0.23 11.3 3.6 0.13 12.1 0.7 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase Orexin_rec2 PF03827.13 GAN00757.1 - 0.028 14.4 0.2 0.92 9.6 0.2 2.3 1 1 1 2 2 2 0 Orexin receptor type 2 JmjC PF02373.22 GAN00758.1 - 1.3e-14 54.5 2.9 4.6e-14 52.8 0.1 3.2 3 2 0 3 3 3 1 JmjC domain, hydroxylase ZZ PF00569.17 GAN00758.1 - 0.0062 16.3 13.8 0.0062 16.3 13.8 3.8 3 1 0 3 3 3 1 Zinc finger, ZZ type Cupin_2 PF07883.11 GAN00758.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain RabGAP-TBC PF00566.18 GAN00759.1 - 1.2e-47 162.3 1.2 1.2e-47 162.3 1.2 2.9 3 1 1 4 4 4 1 Rab-GTPase-TBC domain SPAM PF02090.15 GAN00759.1 - 0.003 17.4 7.1 0.003 17.4 7.1 2.7 2 1 1 3 3 3 1 Salmonella surface presentation of antigen gene type M protein DUF724 PF05266.14 GAN00759.1 - 0.0031 17.4 10.4 0.0031 17.4 10.4 3.1 3 1 1 4 4 4 1 Protein of unknown function (DUF724) Cep57_CLD_2 PF14197.6 GAN00759.1 - 0.014 15.4 9.5 0.014 15.4 9.5 3.8 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 HEPN_Toprim_N PF18871.1 GAN00759.1 - 0.022 14.7 0.2 0.022 14.7 0.2 2.8 3 0 0 3 3 3 0 HEPN/Toprim N-terminal domain 1 Gp-FAR-1 PF05823.12 GAN00759.1 - 0.046 14.1 13.1 0.41 11.0 7.9 4.1 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1664 PF07889.12 GAN00759.1 - 0.066 13.3 9.9 0.033 14.2 3.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 GAN00759.1 - 0.13 12.3 22.1 0.32 11.0 20.7 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1195 PF06708.11 GAN00759.1 - 0.32 10.8 2.8 0.56 10.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) COG5 PF10392.9 GAN00759.1 - 1.1 9.4 15.9 0.24 11.6 0.4 3.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 BLI1 PF17324.2 GAN00759.1 - 1.2 9.8 12.1 4.9 7.9 3.0 2.6 2 0 0 2 2 2 0 BLOC-1 interactor 1 BRE1 PF08647.11 GAN00759.1 - 2.4 8.3 28.6 1 9.5 2.6 3.3 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Bap31_Bap29_C PF18035.1 GAN00759.1 - 3 7.9 9.5 8.8 6.4 2.4 4.1 2 1 2 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain FUSC PF04632.12 GAN00759.1 - 3 6.2 4.5 5.3 5.5 4.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1515 PF07439.11 GAN00759.1 - 6.5 6.8 6.1 1.6 8.8 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4201 PF13870.6 GAN00759.1 - 6.6 6.4 27.4 0.13 12.0 9.8 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 GAN00759.1 - 7 6.8 39.0 0.54 10.5 12.2 3.8 3 1 1 4 4 3 0 Autophagy protein 16 (ATG16) HTH_Tnp_Tc5 PF03221.16 GAN00760.1 - 0.0049 16.9 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Phosphorylase PF00343.20 GAN00762.1 - 0 1032.6 0.0 0 1032.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase FMO-like PF00743.19 GAN00763.1 - 2.7e-45 154.8 0.0 3.9e-27 94.9 0.1 4.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAN00763.1 - 7e-17 61.6 0.0 3.3e-11 43.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAN00763.1 - 8e-13 48.3 0.0 2.7e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAN00763.1 - 8.1e-09 35.1 0.0 6.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN00763.1 - 4.9e-08 33.1 0.0 9.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAN00763.1 - 9.7e-06 25.7 0.0 0.00021 21.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 GAN00763.1 - 1e-05 25.3 0.1 0.0012 18.5 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAN00763.1 - 2.1e-05 24.0 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAN00763.1 - 2.6e-05 23.1 0.1 4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 GAN00763.1 - 4.3e-05 24.0 1.9 0.015 15.8 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAN00763.1 - 0.00028 20.1 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAN00763.1 - 0.00029 20.2 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 GAN00763.1 - 0.0014 19.1 0.1 0.81 10.2 0.0 2.8 3 0 0 3 3 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 GAN00763.1 - 0.0052 16.1 0.1 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAN00763.1 - 0.0089 15.4 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1188 PF06690.11 GAN00763.1 - 0.022 14.3 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) IlvN PF07991.12 GAN00763.1 - 0.034 13.7 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 GAN00763.1 - 0.047 13.0 0.3 0.1 11.9 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 GAN00763.1 - 0.07 13.2 0.0 0.79 9.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 GAN00763.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 GAN00763.1 - 0.12 11.5 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAN00763.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 GAN00763.1 - 0.19 11.6 0.0 0.5 10.2 0.0 1.6 1 1 0 1 1 1 0 YjeF-related protein N-terminus 7tm_3 PF00003.22 GAN00764.1 - 5.2e-40 137.6 26.6 9e-40 136.9 26.6 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 GAN00764.1 - 1.3e-39 136.3 0.2 3.2e-39 135.0 0.2 1.6 1 0 0 1 1 1 1 Receptor family ligand binding region DIL PF01843.19 GAN00764.1 - 7.6e-28 96.8 2.1 7.6e-28 96.8 2.1 2.4 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 GAN00764.1 - 3e-15 56.6 0.0 1.1e-14 54.8 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Peripla_BP_6 PF13458.6 GAN00764.1 - 4.3e-14 52.9 0.5 7.4e-14 52.2 0.5 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Ank PF00023.30 GAN00764.1 - 8.3e-12 45.0 0.1 0.00011 22.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAN00764.1 - 9e-08 32.5 0.0 4.2e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN00764.1 - 1.2e-07 31.5 0.0 0.041 14.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAN00764.1 - 2.7e-07 30.7 0.0 0.00065 19.9 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) COX15-CtaA PF02628.15 GAN00765.1 - 3e-102 342.0 1.4 3.6e-102 341.8 1.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Arrestin_C PF02752.22 GAN00766.1 - 4e-06 27.3 5.7 0.00016 22.1 0.6 3.2 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN00766.1 - 0.00014 21.9 0.0 0.0062 16.6 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF1933 PF09147.10 GAN00766.1 - 0.0015 18.1 0.4 0.0033 17.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1933) Rtt106_N PF18215.1 GAN00766.1 - 0.044 13.5 0.5 0.16 11.7 0.4 2.0 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain BTB_2 PF02214.22 GAN00767.1 - 0.0014 18.9 0.1 0.019 15.3 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain Peptidase_M99_m PF17130.4 GAN00767.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 TPT PF03151.16 GAN00768.1 - 1.6e-61 208.2 28.3 1.8e-61 208.0 28.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN00768.1 - 3.6e-10 40.1 34.8 1.5e-05 25.2 15.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAN00768.1 - 4e-10 39.4 30.8 6.2e-10 38.8 30.8 1.2 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 GAN00768.1 - 0.52 11.0 11.1 0.082 13.6 3.0 2.7 2 1 0 2 2 2 0 Small Multidrug Resistance protein CPP1-like PF11833.8 GAN00768.1 - 1 9.0 4.3 0.53 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3021 PF11457.8 GAN00768.1 - 4.6 7.6 30.9 1.4 9.2 9.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) iPGM_N PF06415.13 GAN00769.1 - 1.8e-76 256.4 0.0 2.5e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 GAN00769.1 - 3.1e-76 256.0 0.1 3.6e-76 255.8 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 GAN00769.1 - 2.8e-06 27.2 0.0 5.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAN00769.1 - 0.00022 20.7 0.0 0.00041 19.8 0.0 1.6 1 0 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 GAN00769.1 - 0.0078 15.2 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Alkaline phosphatase PglZ PF08665.12 GAN00769.1 - 0.037 14.1 0.0 0.094 12.8 0.0 1.6 2 0 0 2 2 2 0 PglZ domain 2OG-FeII_Oxy_3 PF13640.6 GAN00771.1 - 6.6e-16 59.0 0.0 2.1e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAN00771.1 - 1.7e-06 28.6 0.0 3.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ferritin PF00210.24 GAN00772.1 - 7.3e-20 71.3 0.3 9.2e-20 71.0 0.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain Hormone_1 PF00103.20 GAN00772.1 - 0.074 12.8 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Somatotropin hormone family Arrestin_N PF00339.29 GAN00773.1 - 2.2e-11 44.0 0.0 1.4e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Tox-HNH-EHHH PF15657.6 GAN00774.1 - 0.052 13.9 0.2 0.1 13.0 0.2 1.7 1 1 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxins ribosomal_L24 PF17136.4 GAN00774.1 - 0.063 13.7 0.2 0.99 9.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 Usp PF00582.26 GAN00775.1 - 0.017 15.7 0.0 0.018 15.5 0.0 1.1 1 0 0 1 1 1 0 Universal stress protein family NUFIP1 PF10453.9 GAN00776.1 - 3e-13 49.4 3.9 3e-13 49.4 3.9 2.8 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 GAN00776.1 - 9.1e-06 25.6 5.8 1.6e-05 24.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAN00776.1 - 4.9e-05 23.1 4.8 9.4e-05 22.2 4.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAN00776.1 - 0.00017 21.3 5.4 0.00035 20.3 5.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 GAN00776.1 - 0.02 15.6 3.9 0.02 15.6 3.9 2.8 2 2 0 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 GAN00776.1 - 0.043 14.0 0.6 0.18 12.0 0.6 2.0 1 0 0 1 1 1 0 Zinc-finger containing family TFIIA PF03153.13 GAN00776.1 - 1.9 8.4 24.6 3.3 7.6 24.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNARE PF05739.19 GAN00777.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 SNARE domain SKN1 PF03935.15 GAN00777.1 - 0.04 12.3 1.0 0.077 11.4 0.0 1.7 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) DUF5362 PF17319.2 GAN00777.1 - 0.044 13.6 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5362) Mre11_DNA_bind PF04152.14 GAN00779.1 - 1.1e-42 146.2 0.1 1.1e-42 146.2 0.1 2.5 3 1 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GAN00779.1 - 3.6e-14 53.7 1.9 5.8e-14 53.1 1.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAN00779.1 - 0.0018 18.5 0.0 0.0075 16.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Tom22 PF04281.13 GAN00780.1 - 1e-36 125.8 2.8 1.8e-36 125.0 2.8 1.4 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GvpG PF05120.12 GAN00780.1 - 2.6 8.1 6.5 0.29 11.2 1.9 1.9 2 1 0 2 2 2 0 Gas vesicle protein G DUF5487 PF17589.2 GAN00781.1 - 0.025 14.8 0.5 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5487) FliD_N PF02465.18 GAN00781.1 - 0.094 13.4 2.1 0.14 12.8 1.8 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus LAGLIDADG_2 PF03161.13 GAN00782.1 - 0.052 13.6 5.3 0.26 11.3 0.5 2.4 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family C2 PF00168.30 GAN00783.1 - 6.6e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain SRP-alpha_N PF04086.13 GAN00783.1 - 8.6 6.2 26.4 16 5.3 26.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MMS1_N PF10433.9 GAN00785.1 - 1e-162 542.2 0.0 1.3e-162 541.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAN00785.1 - 1.3e-91 307.3 0.0 4.1e-90 302.4 0.0 2.2 2 0 0 2 2 2 2 CPSF A subunit region TPR_2 PF07719.17 GAN00786.1 - 3.3e-10 39.3 0.1 0.0052 16.8 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN00786.1 - 5.3e-05 22.9 0.7 4.5 7.3 1.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN00786.1 - 0.00014 22.3 0.1 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAN00786.1 - 0.0011 19.0 0.7 0.067 13.4 0.0 3.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN00786.1 - 0.0026 17.4 0.1 0.78 9.5 0.7 3.0 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 GAN00786.1 - 0.0034 17.6 0.2 10 6.5 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAN00786.1 - 0.0037 17.8 0.0 0.15 12.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat GMP_synt_C PF00958.22 GAN00786.1 - 0.0058 16.6 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 GMP synthase C terminal domain ANAPC3 PF12895.7 GAN00786.1 - 0.01 16.1 0.1 0.039 14.2 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAN00786.1 - 0.012 16.2 0.0 1.3 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN00786.1 - 0.031 15.1 0.1 1 10.4 0.0 2.8 2 2 1 3 3 3 0 Tetratricopeptide repeat DUF488 PF04343.13 GAN00786.1 - 0.051 14.2 0.5 0.075 13.6 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF488 RsbRD_N PF14361.6 GAN00786.1 - 0.074 13.8 0.3 0.91 10.3 0.1 2.0 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Ribosomal_S24e PF01282.19 GAN00786.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S24e DUF202 PF02656.15 GAN00787.1 - 2.1e-16 60.1 2.0 9.2e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cytochrom_B561 PF03188.16 GAN00787.1 - 0.051 13.7 3.7 0.083 13.0 3.7 1.4 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 zf-tcix PF14952.6 GAN00787.1 - 0.13 11.9 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF3021 PF11457.8 GAN00787.1 - 0.96 9.8 12.9 12 6.2 12.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) TctB PF07331.11 GAN00787.1 - 6 7.1 10.1 2.8 8.2 1.1 2.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family zf-RING_2 PF13639.6 GAN00788.1 - 3.3e-10 40.1 9.9 6e-10 39.3 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 GAN00788.1 - 2.9e-07 30.4 0.0 6.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 GAN00788.1 - 6.5e-07 29.1 9.6 1.2e-06 28.2 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN00788.1 - 5.9e-06 25.9 9.2 5.9e-06 25.9 9.2 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAN00788.1 - 7.6e-06 25.7 8.9 1.3e-05 24.9 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN00788.1 - 1.8e-05 24.9 6.9 4.3e-05 23.7 6.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAN00788.1 - 0.057 13.5 2.7 0.14 12.2 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAN00788.1 - 0.28 11.1 9.8 0.46 10.4 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN00788.1 - 1 9.4 7.2 1.7 8.6 7.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN00788.1 - 2.5 8.0 10.7 4.8 7.1 10.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 adh_short_C2 PF13561.6 GAN00789.1 - 1.5e-51 175.2 0.2 2.2e-51 174.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN00789.1 - 7.1e-42 143.1 0.5 8.8e-42 142.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN00789.1 - 8.1e-13 48.7 1.3 1.1e-12 48.2 1.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAN00789.1 - 0.006 15.8 0.7 0.0081 15.3 0.7 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 GAN00789.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) bZIP_2 PF07716.15 GAN00790.1 - 1.5e-10 41.0 11.6 1.5e-10 41.0 11.6 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN00790.1 - 0.0038 17.3 9.6 0.01 15.9 9.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor CDC27 PF09507.10 GAN00790.1 - 0.017 14.5 10.9 0.02 14.3 10.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 XhlA PF10779.9 GAN00790.1 - 0.038 14.2 2.6 0.083 13.1 2.6 1.5 1 0 0 1 1 1 0 Haemolysin XhlA RRM_3 PF08777.11 GAN00790.1 - 0.12 12.4 2.8 0.23 11.5 2.8 1.5 1 0 0 1 1 1 0 RNA binding motif TFIIA PF03153.13 GAN00790.1 - 0.17 11.9 15.9 0.2 11.6 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PP_kinase PF02503.17 GAN00790.1 - 0.18 11.4 4.3 0.37 10.4 4.3 1.5 1 0 0 1 1 1 0 Polyphosphate kinase middle domain Ndc1_Nup PF09531.10 GAN00790.1 - 4.3 5.9 12.6 5.4 5.6 12.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bromodomain PF00439.25 GAN00791.1 - 1.9e-18 66.3 1.0 4.5e-18 65.1 1.0 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 GAN00791.1 - 1.4e-11 44.2 0.1 2.7e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 GAN00791.1 - 0.0034 17.5 0.1 0.024 14.8 0.0 2.6 2 0 0 2 2 2 1 Histone-fold protein PUF PF00806.19 GAN00792.1 - 6.3e-63 205.1 18.5 1.1e-08 34.3 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SET PF00856.28 GAN00792.1 - 3.4 8.0 8.5 0.18 12.2 0.5 2.4 2 1 0 2 2 2 0 SET domain tRNA_bind PF01588.20 GAN00793.1 - 2.8e-29 101.0 0.5 7.9e-29 99.6 0.1 2.0 2 1 1 3 3 3 1 Putative tRNA binding domain GST_C_3 PF14497.6 GAN00793.1 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAN00793.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN00793.1 - 0.0021 18.3 1.0 0.0057 16.8 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Prot_ATP_ID_OB PF16450.5 GAN00793.1 - 0.017 15.1 0.2 0.05 13.6 0.0 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain GST_C_2 PF13410.6 GAN00793.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IHABP4_N PF16174.5 GAN00793.1 - 0.22 12.1 9.1 0.39 11.3 9.1 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Ras PF00071.22 GAN00794.1 - 1.9e-60 203.1 0.1 2.3e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN00794.1 - 4.8e-21 75.2 0.0 7.5e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN00794.1 - 7.6e-08 32.0 0.0 8.5e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN00794.1 - 0.00025 20.6 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN00794.1 - 0.00058 19.8 0.1 0.92 9.4 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 GAN00794.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain 2Fe-2S_thioredx PF01257.19 GAN00794.1 - 0.027 14.3 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin G-alpha PF00503.20 GAN00794.1 - 0.032 13.4 0.0 6.8 5.7 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit CTP_transf_3 PF02348.19 GAN00794.1 - 0.073 13.0 0.5 0.82 9.5 0.1 2.0 2 0 0 2 2 2 0 Cytidylyltransferase FeoB_N PF02421.18 GAN00794.1 - 0.079 12.5 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Oxysterol_BP PF01237.18 GAN00795.1 - 2.5e-88 296.4 0.3 2.9e-86 289.6 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein MIR PF02815.19 GAN00796.1 - 2.9e-17 63.1 0.1 4e-13 49.6 0.1 2.6 2 0 0 2 2 2 2 MIR domain Med26 PF08711.11 GAN00796.1 - 9.6e-12 44.7 0.0 2.4e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ins145_P3_rec PF08709.11 GAN00796.1 - 0.0038 16.5 0.0 0.0095 15.1 0.0 1.7 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF148 PF02520.17 GAN00796.1 - 0.31 11.2 2.7 0.26 11.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 Ribosomal_60s PF00428.19 GAN00797.1 - 1.8e-25 89.3 10.7 2.1e-25 89.1 10.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein PH_4 PF15404.6 GAN00798.1 - 4e-21 75.6 6.5 6.9e-19 68.3 2.9 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAN00798.1 - 8.6e-09 35.9 5.6 6.9e-05 23.3 0.2 4.9 4 2 0 4 4 4 2 PH domain DUF1770 PF08589.10 GAN00799.1 - 0.0032 18.4 0.3 0.0043 18.0 0.3 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF2407_C PF13373.6 GAN00799.1 - 0.069 13.3 0.0 0.1 12.8 0.0 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain MTS PF05175.14 GAN00800.1 - 2.2e-06 27.4 0.0 5.8e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAN00800.1 - 0.0046 16.8 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN00800.1 - 0.0056 17.4 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAN00800.1 - 0.0076 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 GAN00800.1 - 0.011 15.4 0.3 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase DUF938 PF06080.12 GAN00800.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF1216 PF06746.11 GAN00800.1 - 0.3 11.1 1.0 2.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) DAHP_synth_1 PF00793.20 GAN00801.1 - 2e-105 351.6 0.1 2.3e-105 351.4 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PriA_C PF18074.1 GAN00801.1 - 0.11 13.4 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain Pkinase PF00069.25 GAN00802.1 - 3.2e-71 239.8 0.0 5.2e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00802.1 - 8.5e-38 130.1 0.0 1.5e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAN00802.1 - 1e-13 50.8 0.1 2.1e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 GAN00802.1 - 5.8e-07 29.1 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN00802.1 - 0.0068 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN00802.1 - 0.013 14.5 0.1 0.027 13.4 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 GAN00802.1 - 0.036 13.7 1.0 0.061 12.9 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 GAN00802.1 - 0.048 13.0 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NT5C PF06941.12 GAN00803.1 - 8.7e-10 38.8 0.7 8.7e-10 38.8 0.7 1.5 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD PF12710.7 GAN00803.1 - 0.0013 19.2 0.2 0.0045 17.4 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN00803.1 - 0.0019 18.3 0.3 0.0093 16.1 0.1 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase E2_bind PF08825.10 GAN00803.1 - 0.039 14.1 0.1 0.09 12.9 0.1 1.6 2 0 0 2 2 2 0 E2 binding domain Hydrolase PF00702.26 GAN00803.1 - 0.1 12.8 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Homeobox_KN PF05920.11 GAN00804.1 - 5.5e-17 61.4 1.1 1.3e-16 60.2 1.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAN00804.1 - 2.5e-05 24.0 1.7 4.4e-05 23.2 0.3 2.1 2 0 0 2 2 2 1 Homeodomain CDC45 PF02724.14 GAN00804.1 - 0.00054 18.4 10.2 0.00065 18.1 10.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.11 GAN00804.1 - 0.0014 16.8 9.3 0.0019 16.4 9.3 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nop53 PF07767.11 GAN00804.1 - 0.0025 17.3 10.2 0.0042 16.5 10.2 1.4 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 GAN00804.1 - 0.0027 17.2 10.1 0.0034 16.9 10.1 1.3 1 0 0 1 1 1 1 SDA1 Merozoite_SPAM PF07133.11 GAN00804.1 - 0.0035 17.4 14.5 0.0062 16.6 14.5 1.4 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) FRQ PF09421.10 GAN00804.1 - 0.0035 15.5 8.8 0.005 14.9 8.8 1.2 1 0 0 1 1 1 1 Frequency clock protein CDC27 PF09507.10 GAN00804.1 - 0.022 14.2 12.0 0.033 13.6 12.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LAP1C PF05609.12 GAN00804.1 - 0.039 13.1 7.4 0.047 12.8 7.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_phi PF04931.13 GAN00804.1 - 0.059 11.5 15.4 0.084 11.0 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAN00804.1 - 0.076 11.2 14.9 0.11 10.7 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GAN00804.1 - 0.086 12.9 17.8 0.038 14.1 15.4 1.5 1 1 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 GAN00804.1 - 0.29 9.6 5.7 0.26 9.8 4.3 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 GAN00804.1 - 0.31 11.3 14.0 0.64 10.3 14.0 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NOA36 PF06524.12 GAN00804.1 - 0.58 9.4 12.7 0.92 8.8 12.7 1.3 1 0 0 1 1 1 0 NOA36 protein MscS_TM PF12794.7 GAN00804.1 - 0.7 8.7 4.1 1.1 8.1 4.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Astro_capsid_p PF12226.8 GAN00804.1 - 0.7 9.0 10.0 1.2 8.3 10.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TFB6 PF17110.5 GAN00804.1 - 3 7.6 7.9 69 3.1 8.3 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CBM_21 PF03370.13 GAN00805.1 - 2.4e-25 88.9 4.6 8.2e-25 87.2 1.2 2.3 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAN00805.1 - 7e-11 42.6 0.6 1.9e-10 41.2 0.6 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MFS_1 PF07690.16 GAN00806.1 - 4.9e-32 111.2 45.2 4.9e-32 111.2 45.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN00806.1 - 3.5e-10 39.3 16.1 3.5e-10 39.3 16.1 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAN00806.1 - 5.6e-09 35.0 21.1 5.6e-09 35.0 21.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 GAN00806.1 - 0.34 11.1 11.1 0.063 13.4 2.2 3.0 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Chordopox_A13L PF05961.11 GAN00806.1 - 0.56 10.5 3.1 0.78 10.0 0.3 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein CotH PF08757.11 GAN00807.1 - 1.8e-35 123.1 6.2 2.8e-34 119.1 6.2 2.1 1 1 0 1 1 1 1 CotH kinase protein Glyco_hydro_15 PF00723.21 GAN00808.1 - 8.6e-84 281.9 0.3 1.1e-83 281.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_21 PF03370.13 GAN00808.1 - 1.3e-10 41.4 4.7 3.5e-10 40.0 4.7 1.8 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAN00808.1 - 2.7e-05 24.6 5.6 0.00011 22.7 5.6 2.1 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) FAA_hydrolase PF01557.18 GAN00809.1 - 2.3e-57 194.2 0.0 2.6e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family tRNA-synt_His PF13393.6 GAN00811.1 - 2.7e-41 141.8 0.0 3.3e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GAN00811.1 - 4.3e-15 55.6 0.1 9.4e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 GAN00811.1 - 3.8e-07 29.9 0.1 5.8e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 GAN00811.1 - 1e-06 28.8 0.0 9.7e-06 25.7 0.0 2.4 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 GAN00811.1 - 1.1e-05 24.7 0.2 0.0021 17.2 0.1 2.6 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 GAN00811.1 - 0.0038 16.7 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Glyco_hydro_9 PF00759.19 GAN00812.1 - 8.9e-115 384.4 17.9 1e-114 384.2 17.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF4381 PF14316.6 GAN00812.1 - 0.2 11.9 1.4 0.38 11.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) BCNT PF07572.12 GAN00813.1 - 6.8e-22 77.3 3.4 6.8e-22 77.3 3.4 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development CDC45 PF02724.14 GAN00813.1 - 0.2 9.9 13.2 0.23 9.7 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 GAN00813.1 - 0.45 9.1 9.8 0.49 9.0 9.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRN3 PF05327.11 GAN00813.1 - 1.2 7.6 9.8 1.4 7.4 9.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 GAN00813.1 - 9.2 5.6 31.6 27 4.1 31.6 1.7 1 1 0 1 1 1 0 SDA1 Oxysterol_BP PF01237.18 GAN00814.1 - 9.2e-66 222.2 0.5 1.4e-63 215.0 0.5 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Lipoprotein_18 PF06804.11 GAN00814.1 - 0.025 13.7 0.2 0.036 13.1 0.2 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein A_deaminase PF00962.22 GAN00815.1 - 2e-33 116.1 0.1 4.6e-33 114.9 0.1 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 GAN00815.1 - 0.0037 16.6 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family ADK PF00406.22 GAN00816.1 - 6.1e-13 49.1 1.0 1.1e-11 45.1 1.0 2.9 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAN00816.1 - 1.4e-05 25.6 0.0 3.8e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAN00816.1 - 0.092 13.3 0.1 0.51 10.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain ABC1 PF03109.16 GAN00817.1 - 2.9e-32 111.3 0.2 5.9e-32 110.3 0.2 1.5 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 GAN00817.1 - 8.9e-06 25.5 0.2 2.3e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 GAN00817.1 - 9.5e-05 22.4 0.0 0.0043 17.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAN00817.1 - 0.0081 15.6 0.1 0.05 13.0 0.1 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 GAN00817.1 - 0.034 12.9 0.1 0.046 12.5 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Rho_RNA_bind PF07497.12 GAN00817.1 - 0.099 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain GTP_EFTU PF00009.27 GAN00818.1 - 2.1e-47 161.2 1.4 2.4e-47 161.0 1.4 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN00818.1 - 6e-05 23.1 0.2 0.0019 18.3 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Neisseria_TspB PF05616.13 GAN00818.1 - 0.046 12.2 0.1 0.065 11.7 0.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Dynamin_N PF00350.23 GAN00818.1 - 0.066 13.3 0.1 10 6.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 GAN00818.1 - 0.078 12.5 0.8 1.8 8.1 0.2 2.8 1 1 1 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 GAN00818.1 - 0.1 11.7 0.1 0.3 10.2 0.1 1.7 1 1 0 2 2 2 0 G-protein alpha subunit WWE PF02825.20 GAN00819.1 - 0.0036 17.9 0.6 0.0043 17.6 0.6 1.2 1 0 0 1 1 1 1 WWE domain DUF2787 PF10980.8 GAN00819.1 - 0.074 13.2 0.1 0.087 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) HATPase_c PF02518.26 GAN00820.1 - 1.1e-29 103.1 0.1 3e-29 101.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAN00820.1 - 2.2e-22 79.3 0.5 5.7e-21 74.8 0.0 3.6 4 0 0 4 4 3 1 Response regulator receiver domain AAA_16 PF13191.6 GAN00820.1 - 1.2e-17 64.9 0.0 1e-16 61.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 GAN00820.1 - 2e-16 59.8 0.4 8.6e-16 57.7 0.0 2.4 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 GAN00820.1 - 7.9e-15 54.9 0.0 2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00820.1 - 7.6e-08 32.0 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_22 PF13401.6 GAN00820.1 - 4.2e-05 23.8 0.0 0.00055 20.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain GAF PF01590.26 GAN00820.1 - 0.002 18.8 0.0 0.0055 17.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 GAN00820.1 - 0.0052 16.0 0.2 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 GAN00820.1 - 0.0054 17.2 0.0 0.031 14.8 0.0 2.3 1 0 0 1 1 1 1 ABC transporter GAF_2 PF13185.6 GAN00820.1 - 0.0067 16.7 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 GAF domain ATPase_2 PF01637.18 GAN00820.1 - 0.014 15.3 2.2 0.032 14.1 0.3 2.8 2 1 0 2 2 1 0 ATPase domain predominantly from Archaea TPR_12 PF13424.6 GAN00820.1 - 0.033 14.5 0.7 0.15 12.3 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RsgA_GTPase PF03193.16 GAN00820.1 - 0.043 13.7 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 GAN00820.1 - 0.083 12.8 0.9 1.1 9.2 0.2 3.1 2 1 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 GAN00820.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Stealth_CR1 PF17101.5 GAN00820.1 - 0.2 11.5 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 FAM91_N PF14647.6 GAN00820.1 - 0.32 10.2 2.7 2.9 7.1 0.3 2.5 2 0 0 2 2 2 0 FAM91 N-terminus DUF87 PF01935.17 GAN00820.1 - 0.39 10.8 2.0 1.6 8.8 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain zf-CCCH PF00642.24 GAN00821.1 - 2.2e-09 37.0 32.0 3.9e-06 26.6 5.1 5.0 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAN00821.1 - 9.8e-07 28.6 27.6 0.00026 20.9 4.6 5.8 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH_3 PF15663.5 GAN00821.1 - 0.016 15.4 18.3 0.47 10.7 4.3 3.5 1 1 2 3 3 3 0 Zinc-finger containing family MINDY_DUB PF04424.13 GAN00822.1 - 1.8e-34 118.3 0.0 4.8e-34 116.9 0.0 1.8 1 1 0 1 1 1 1 MINDY deubiquitinase HSF_DNA-bind PF00447.17 GAN00823.1 - 3.3e-29 101.3 3.1 3e-28 98.3 2.2 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding PAC3 PF10178.9 GAN00824.1 - 1.2e-21 76.7 0.1 1.5e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DEAD PF00270.29 GAN00825.1 - 2.3e-43 148.0 0.1 4e-43 147.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 GAN00825.1 - 2.3e-22 79.0 0.1 6.3e-22 77.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 GAN00825.1 - 7.8e-21 74.5 0.0 9.6e-20 71.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN00825.1 - 9.8e-09 35.4 0.0 9.8e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAN00825.1 - 0.0012 19.1 0.0 0.0053 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 GAN00825.1 - 0.081 12.2 0.0 0.081 12.2 0.0 2.9 3 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit ABC_membrane_2 PF06472.15 GAN00827.1 - 1.6e-98 329.4 3.9 3.1e-98 328.5 3.9 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 DUF4042 PF13251.6 GAN00827.1 - 5.3e-32 111.0 0.5 1.5e-30 106.2 0.1 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4042) ABC_tran PF00005.27 GAN00827.1 - 1.6e-18 67.5 0.0 5.7e-18 65.7 0.0 2.0 1 0 0 1 1 1 1 ABC transporter HEAT PF02985.22 GAN00827.1 - 2.9e-13 48.8 15.7 0.0037 17.4 0.2 8.9 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 GAN00827.1 - 5e-13 49.2 4.8 0.002 18.6 0.7 7.5 7 2 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 GAN00827.1 - 1.6e-12 47.6 1.2 2e-05 24.9 0.2 6.1 6 0 0 6 6 6 2 HEAT repeats AAA_21 PF13304.6 GAN00827.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN00827.1 - 0.0092 15.4 0.3 0.33 10.4 0.1 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAN00827.1 - 0.029 14.9 0.0 0.029 14.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain Telomere_reg-2 PF10193.9 GAN00827.1 - 0.091 13.2 0.1 0.71 10.3 0.0 2.7 2 0 0 2 2 1 0 Telomere length regulation protein Arm PF00514.23 GAN00827.1 - 0.097 12.8 8.1 60 3.9 0.1 6.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat AAA_29 PF13555.6 GAN00827.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP11 PF06644.11 GAN00828.1 - 3.1e-67 227.2 5.8 3.6e-67 227.0 5.8 1.0 1 0 0 1 1 1 1 ATP11 protein RHH_4 PF13467.6 GAN00828.1 - 0.011 15.6 0.1 0.029 14.2 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain Dimerisation2 PF16864.5 GAN00828.1 - 0.035 14.1 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain SurA_N PF09312.11 GAN00828.1 - 0.05 13.7 0.1 0.097 12.7 0.1 1.6 1 0 0 1 1 1 0 SurA N-terminal domain Histone_HNS PF00816.21 GAN00828.1 - 0.078 13.8 4.5 0.16 12.8 4.5 1.5 1 0 0 1 1 1 0 H-NS histone family RNase_J_C PF17770.1 GAN00828.1 - 0.2 12.7 2.3 12 7.0 0.9 2.7 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain Rotamase_2 PF13145.6 GAN00828.1 - 0.83 10.5 10.2 0.22 12.4 5.6 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain 60KD_IMP PF02096.20 GAN00829.1 - 5e-29 101.3 1.6 5e-29 101.3 1.6 1.9 1 1 1 2 2 2 1 60Kd inner membrane protein STI1 PF17830.1 GAN00829.1 - 0.16 11.9 1.8 0.5 10.3 0.1 2.5 2 0 0 2 2 2 0 STI1 domain DUF948 PF06103.11 GAN00829.1 - 1.3 9.3 5.1 14 6.0 0.2 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 GAN00829.1 - 3.6 8.2 5.2 42 4.8 0.2 2.4 2 0 0 2 2 2 0 YtxH-like protein Choline_transpo PF04515.12 GAN00830.1 - 2.6e-59 201.1 29.8 2.6e-59 201.1 29.8 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter SPC25 PF06703.11 GAN00830.1 - 9.1 6.0 10.1 0.41 10.4 2.7 2.5 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PUF PF00806.19 GAN00831.1 - 1.3e-55 182.0 17.7 4.1e-09 35.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf_CCCH_4 PF18345.1 GAN00831.1 - 0.0013 18.7 4.4 0.0036 17.3 4.4 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAN00831.1 - 0.0017 18.2 1.2 0.0043 16.9 1.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) COPI_assoc PF08507.10 GAN00832.1 - 1.8e-16 60.4 15.7 2.4e-16 60.0 15.7 1.1 1 0 0 1 1 1 1 COPI associated protein Phage_holin_2_4 PF16082.5 GAN00832.1 - 0.12 12.1 0.7 0.12 12.1 0.7 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like F-box-like PF12937.7 GAN00833.1 - 3.9e-06 26.7 0.9 7.7e-06 25.7 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN00833.1 - 0.0029 17.4 0.5 0.0064 16.3 0.5 1.6 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.6 GAN00833.1 - 0.012 15.2 0.2 0.022 14.4 0.2 1.4 1 0 0 1 1 1 0 TPR repeat TPR_MalT PF17874.1 GAN00833.1 - 0.014 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region TPR_2 PF07719.17 GAN00833.1 - 0.028 14.5 0.0 0.028 14.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN00833.1 - 0.039 13.8 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5031 PF16434.5 GAN00833.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) JAB PF01398.21 GAN00834.1 - 2.1e-34 118.0 0.5 2.1e-34 118.0 0.5 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 GAN00834.1 - 8.1e-18 65.1 2.6 2.1e-17 63.8 2.6 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 GAN00834.1 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 GAN00834.1 - 0.029 14.4 0.6 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) ACC_central PF08326.12 GAN00835.1 - 1.5e-240 800.3 0.8 2e-240 800.0 0.8 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 GAN00835.1 - 3.2e-173 576.9 0.0 4.9e-173 576.3 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAN00835.1 - 5.6e-53 179.6 0.0 1.2e-52 178.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAN00835.1 - 3.3e-28 98.4 0.1 6.8e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN00835.1 - 3.9e-21 75.2 0.0 5.1e-20 71.6 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAN00835.1 - 4.2e-15 55.3 0.1 8.7e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 GAN00835.1 - 0.00014 22.0 0.1 0.00055 20.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAN00835.1 - 0.0045 16.8 0.0 0.016 15.0 0.0 2.0 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 GAN00835.1 - 0.032 13.8 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAN00835.1 - 0.036 13.6 0.0 0.093 12.2 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAN00835.1 - 0.088 12.6 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF1539 PF07560.11 GAN00835.1 - 0.14 12.2 0.1 0.43 10.7 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Endostatin PF06482.11 GAN00836.1 - 0.00013 21.6 1.4 0.00016 21.3 1.4 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DPBB_1 PF03330.18 GAN00836.1 - 0.0034 17.6 0.1 0.0034 17.6 0.1 2.1 2 1 0 2 2 2 1 Lytic transglycolase Rtf2 PF04641.12 GAN00836.1 - 0.0054 16.1 4.6 0.0066 15.8 4.6 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Barwin PF00967.17 GAN00836.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Barwin family DUF4718 PF15842.5 GAN00836.1 - 0.012 15.5 5.0 0.016 15.0 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF755 PF05501.11 GAN00836.1 - 0.025 14.9 24.7 0.033 14.5 24.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Macoilin PF09726.9 GAN00836.1 - 0.13 10.8 5.5 0.13 10.8 5.5 1.0 1 0 0 1 1 1 0 Macoilin family AP3D1 PF06375.11 GAN00836.1 - 0.16 12.2 11.6 0.24 11.6 11.6 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 NPR3 PF03666.13 GAN00836.1 - 0.22 10.3 5.9 0.28 10.0 5.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GAN00836.1 - 0.28 9.9 1.7 0.29 9.9 1.7 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 GAN00836.1 - 0.38 10.8 6.1 0.53 10.3 6.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ALMT PF11744.8 GAN00836.1 - 0.45 9.3 4.3 0.52 9.1 4.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MRP-S25 PF13741.6 GAN00836.1 - 0.46 10.0 6.7 0.63 9.6 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 MFS_1 PF07690.16 GAN00837.1 - 2.7e-41 141.7 26.8 8.9e-41 140.0 26.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 GAN00837.1 - 0.016 15.6 0.4 0.016 15.6 0.4 2.9 4 0 0 4 4 4 0 Bacteriophage A118-like holin, Hol118 YL1 PF05764.13 GAN00838.1 - 2.1e-36 126.3 29.0 2.1e-36 126.3 29.0 6.1 4 2 2 6 6 6 1 YL1 nuclear protein YL1_C PF08265.11 GAN00838.1 - 1.3e-13 50.4 0.3 2.3e-13 49.6 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ric8 PF10165.9 GAN00839.1 - 1.1e-99 334.5 0.8 1.5e-99 334.1 0.8 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Abhydrolase_2 PF02230.16 GAN00840.1 - 7e-64 215.6 0.0 8.2e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAN00840.1 - 9e-11 41.5 0.0 1e-05 25.0 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAN00840.1 - 2.9e-08 33.5 0.1 5.9e-07 29.2 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 GAN00840.1 - 6.2e-06 26.0 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAN00840.1 - 0.00011 22.9 0.2 0.00026 21.7 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAN00840.1 - 0.00012 21.8 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 GAN00840.1 - 0.0016 18.0 0.0 0.17 11.3 0.0 2.3 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 GAN00840.1 - 0.0096 15.8 0.0 1.4 8.7 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAN00840.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.20 GAN00840.1 - 0.039 13.6 0.2 11 5.5 0.0 2.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 GAN00840.1 - 0.2 10.8 0.0 1.8 7.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) TMEM208_SND2 PF05620.11 GAN00841.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Proteasome PF00227.26 GAN00842.1 - 7.9e-38 129.8 0.0 9.4e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pribosyltran_N PF13793.6 GAN00843.1 - 1.2e-46 157.4 0.6 6.3e-46 155.1 0.1 2.1 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAN00843.1 - 2.9e-45 154.6 3.5 1.7e-36 126.0 2.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAN00843.1 - 4.6e-12 45.7 2.9 5.1e-12 45.6 0.8 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAN00843.1 - 0.072 12.5 0.3 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Cyt-b5 PF00173.28 GAN00845.1 - 2.9e-19 69.0 0.0 4.4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YBD PF17725.1 GAN00848.1 - 0.049 13.5 0.7 0.088 12.7 0.7 1.3 1 0 0 1 1 1 0 YAP binding domain OTT_1508_deam PF14441.6 GAN00848.1 - 0.14 12.2 2.8 0.61 10.1 2.8 2.1 1 0 0 1 1 1 0 OTT_1508-like deaminase RVT_1 PF00078.27 GAN00849.1 - 3.9e-28 98.5 0.1 5.3e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5082 PF16888.5 GAN00851.1 - 0.031 14.6 2.9 0.073 13.4 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) FH2 PF02181.23 GAN00851.1 - 0.034 13.3 0.5 0.056 12.5 0.5 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DASH_Dam1 PF08653.10 GAN00851.1 - 0.087 12.6 0.7 0.24 11.2 0.7 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF241 PF03087.14 GAN00851.1 - 0.1 12.4 0.1 15 5.4 0.0 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF1664 PF07889.12 GAN00851.1 - 0.2 11.7 0.9 0.42 10.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAN00851.1 - 1.9 8.7 6.9 0.3 11.3 2.0 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RVT_1 PF00078.27 GAN00852.1 - 2.5e-17 63.2 0.0 4.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GAN00852.1 - 5.9e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAN00852.1 - 0.031 14.1 4.9 1.1 9.1 0.3 3.2 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 GAN00853.1 - 1.5e-07 31.2 0.1 3.2e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HORMA PF02301.18 GAN00854.1 - 4.3e-16 59.2 0.0 5.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 HORMA domain AAA PF00004.29 GAN00855.1 - 1.1e-42 145.6 0.0 3e-42 144.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAN00855.1 - 8.5e-28 96.1 0.1 4.6e-27 93.8 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 GAN00855.1 - 2.5e-22 78.7 7.0 2.5e-22 78.7 7.0 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 GAN00855.1 - 3.3e-08 33.2 0.0 1.2e-07 31.4 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 GAN00855.1 - 5.1e-06 27.0 0.2 0.00016 22.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAN00855.1 - 3.2e-05 23.9 0.0 0.00015 21.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAN00855.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAN00855.1 - 6.4e-05 23.2 0.1 0.035 14.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN00855.1 - 0.00019 21.8 0.2 0.023 15.1 0.0 3.5 3 1 1 4 4 4 1 RNA helicase IstB_IS21 PF01695.17 GAN00855.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 GAN00855.1 - 0.00031 20.0 0.0 0.0043 16.3 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 GAN00855.1 - 0.00049 20.1 0.0 0.0015 18.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 GAN00855.1 - 0.00061 19.1 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 GAN00855.1 - 0.0014 19.1 0.2 0.0054 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAN00855.1 - 0.0015 18.3 0.1 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAN00855.1 - 0.0016 18.6 0.1 0.0055 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 GAN00855.1 - 0.0025 17.9 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GAN00855.1 - 0.0085 15.7 1.0 0.9 9.1 0.1 3.2 3 1 0 4 4 3 1 AAA domain AAA_17 PF13207.6 GAN00855.1 - 0.021 15.2 0.0 0.073 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain Bac_DnaA PF00308.18 GAN00855.1 - 0.029 14.2 0.3 6.2 6.6 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein Torsin PF06309.11 GAN00855.1 - 0.031 14.4 0.0 0.085 13.0 0.0 1.7 2 0 0 2 2 1 0 Torsin Mg_chelatase PF01078.21 GAN00855.1 - 0.031 13.6 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 GAN00855.1 - 0.037 13.9 0.6 1.5 8.6 0.0 2.9 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 GAN00855.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 GAN00855.1 - 0.073 13.6 0.1 0.89 10.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter EF-1_beta_acid PF10587.9 GAN00855.1 - 0.083 13.4 0.5 0.083 13.4 0.5 3.1 3 0 0 3 3 2 0 Eukaryotic elongation factor 1 beta central acidic region Sigma54_activat PF00158.26 GAN00855.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 GAN00855.1 - 0.087 12.2 0.0 5.8 6.2 0.0 2.4 1 1 0 2 2 2 0 KaiC AAA_7 PF12775.7 GAN00855.1 - 0.095 12.2 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 GAN00855.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Cytidylate kinase PhoH PF02562.16 GAN00855.1 - 0.14 11.6 0.1 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 GAN00855.1 - 0.17 11.8 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Peptidase_M15_2 PF05951.13 GAN00855.1 - 0.21 11.2 0.5 0.39 10.4 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Use1 PF09753.9 GAN00855.1 - 0.28 10.9 3.4 0.53 10.0 3.4 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 CLPTM1 PF05602.12 GAN00856.1 - 9.9e-157 522.4 0.1 1.3e-156 522.0 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) 2TM PF13239.6 GAN00856.1 - 0.004 17.4 4.8 0.026 14.8 4.1 2.6 2 0 0 2 2 2 1 2TM domain PQ-loop PF04193.14 GAN00856.1 - 0.024 14.4 0.6 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 PQ loop repeat LSM PF01423.22 GAN00857.1 - 1.2e-21 76.1 0.2 1.3e-21 76.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain YEATS PF03366.16 GAN00858.1 - 4.8e-36 122.6 1.0 7e-36 122.1 1.0 1.2 1 0 0 1 1 1 1 YEATS family Val_tRNA-synt_C PF10458.9 GAN00858.1 - 0.07 13.4 0.4 0.12 12.7 0.4 1.3 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm LPP PF04728.13 GAN00858.1 - 0.71 10.3 4.2 1.2 9.6 0.6 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper SH3_1 PF00018.28 GAN00859.1 - 1.8e-06 27.4 1.3 3.2e-06 26.6 1.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN00859.1 - 0.0014 18.5 0.1 0.0026 17.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 GAN00860.1 - 1.4e-08 34.9 0.3 1.4e-08 34.9 0.3 2.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.10 GAN00860.1 - 0.029 13.9 6.2 0.43 10.1 6.2 2.5 1 1 0 1 1 1 0 Vps5 C terminal like Spt20 PF12090.8 GAN00861.1 - 1.4e-30 106.7 0.2 2.1e-20 73.4 0.1 12.5 2 2 2 5 5 5 2 Spt20 family DUF1765 PF08578.10 GAN00862.1 - 1.8e-26 93.1 5.5 6.3e-26 91.3 5.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) bZIP_2 PF07716.15 GAN00863.1 - 1.2e-10 41.3 6.5 1.2e-10 41.3 6.5 3.7 5 0 0 5 5 5 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN00863.1 - 2.5e-09 37.1 5.2 2.5e-09 37.1 5.2 3.3 3 1 1 4 4 4 1 bZIP transcription factor HAP1_N PF04849.13 GAN00863.1 - 0.00014 21.2 4.2 0.00014 21.2 4.2 2.0 2 0 0 2 2 2 1 HAP1 N-terminal conserved region Shugoshin_N PF07558.11 GAN00863.1 - 0.061 13.2 4.9 2.2 8.2 0.4 3.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF3247 PF11607.8 GAN00863.1 - 2 8.8 5.1 1.3 9.3 2.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3247) Ax_dynein_light PF10211.9 GAN00863.1 - 7.7 6.4 20.6 0.89 9.5 5.5 2.4 2 1 0 2 2 2 0 Axonemal dynein light chain UPF0542 PF15086.6 GAN00864.1 - 0.053 13.5 0.1 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 NB PF04159.13 GAN00864.1 - 0.06 13.4 0.1 0.06 13.4 0.1 2.7 3 0 0 3 3 3 0 NB glycoprotein ubiquitin PF00240.23 GAN00864.1 - 0.12 12.2 0.0 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family p450 PF00067.22 GAN00865.1 - 1.1e-85 288.1 0.1 1.4e-85 287.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3974 PF13120.6 GAN00865.1 - 0.061 13.4 0.1 46 4.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3974) PfkB PF00294.24 GAN00866.1 - 2.1e-13 50.2 0.0 3.8e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_C48 PF02902.19 GAN00867.1 - 1.3e-43 149.4 1.8 1.9e-43 148.8 1.8 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RNA_pol_Rpb2_6 PF00562.28 GAN00868.1 - 1.7e-127 425.7 0.1 2.5e-127 425.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAN00868.1 - 1.5e-67 227.0 0.1 2.3e-67 226.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAN00868.1 - 8.1e-48 162.6 0.0 1.9e-47 161.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAN00868.1 - 2.6e-35 120.7 0.1 1.2e-34 118.5 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 GAN00868.1 - 1.9e-25 88.8 0.1 4.7e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GAN00868.1 - 7e-25 87.1 0.2 1.5e-24 86.1 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 GAN00868.1 - 6.5e-23 81.1 0.4 2.3e-22 79.3 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF2318 PF10080.9 GAN00868.1 - 0.093 12.9 0.7 0.24 11.5 0.7 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_2 PF03107.16 GAN00868.1 - 1.5 9.2 3.3 9.2 6.7 3.3 2.2 1 1 0 1 1 1 0 C1 domain Tti2 PF10521.9 GAN00869.1 - 2.9e-20 73.0 0.1 4.6e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Tti2 family DUF5460 PF17544.2 GAN00869.1 - 0.029 13.4 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5460) CDP-OH_P_transf PF01066.21 GAN00870.1 - 3e-18 66.3 0.2 3e-18 66.3 0.2 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FtsX PF02687.21 GAN00870.1 - 2.2 8.8 15.3 0.085 13.3 0.9 3.5 3 1 0 3 3 3 0 FtsX-like permease family Pyr_redox_2 PF07992.14 GAN00871.1 - 1.6e-08 34.2 0.0 4e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN00871.1 - 0.0024 17.9 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAN00871.1 - 0.003 17.8 0.0 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3808 PF10300.9 GAN00872.1 - 8.9e-56 189.6 5.8 1.4e-55 189.0 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) HATPase_c_3 PF13589.6 GAN00873.1 - 3.7e-08 33.3 0.0 1.2e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAN00873.1 - 9.4e-06 26.1 0.3 3.7e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 GAN00873.1 - 4.7e-05 23.2 0.0 4.7e-05 23.2 0.0 3.2 4 0 0 4 4 4 2 MutL C terminal dimerisation domain SUIM_assoc PF16619.5 GAN00873.1 - 0.015 15.4 1.9 0.046 13.8 1.9 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GDC-P PF02347.16 GAN00874.1 - 8.1e-202 670.7 0.1 2.1e-189 629.8 0.1 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 GAN00874.1 - 1.9e-06 27.1 0.2 5.2e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAN00874.1 - 1.5e-05 24.4 0.4 8.2e-05 22.0 0.1 2.1 2 0 0 2 2 2 1 Beta-eliminating lyase Methyltransf_11 PF08241.12 GAN00875.1 - 2.1e-11 44.3 0.0 6.9e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN00875.1 - 2.5e-09 37.7 0.0 1.4e-08 35.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN00875.1 - 6.1e-07 29.0 0.0 1.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAN00875.1 - 9.7e-07 28.9 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 GAN00875.1 - 3e-06 27.1 0.0 1.3e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN00875.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN00875.1 - 0.0013 19.4 0.0 0.09 13.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PilM PF07419.12 GAN00875.1 - 0.019 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 PilM DUF2347 PF09804.9 GAN00875.1 - 0.063 12.8 0.2 0.097 12.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) BCDHK_Adom3 PF10436.9 GAN00876.1 - 2e-54 183.8 0.0 1.8e-53 180.7 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAN00876.1 - 1.2e-11 45.0 0.0 2.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BET PF17035.5 GAN00876.1 - 0.00047 20.3 0.8 0.00095 19.3 0.3 1.8 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation HATPase_c_3 PF13589.6 GAN00876.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 GAN00876.1 - 0.087 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Glyco_hydro_31 PF01055.26 GAN00878.1 - 1.6e-116 390.1 4.0 3.2e-116 389.1 4.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAN00878.1 - 7.8e-31 106.7 1.2 2.3e-30 105.1 1.2 1.8 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase ArfGap PF01412.18 GAN00878.1 - 3.5e-12 46.4 0.0 8.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Gal_mutarotas_2 PF13802.6 GAN00878.1 - 2.5e-07 30.9 0.8 9.5e-07 29.1 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Complex1_30kDa PF00329.19 GAN00879.1 - 7e-46 155.8 0.0 9.8e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HLH PF00010.26 GAN00880.1 - 3.1e-12 46.3 1.2 1.4e-11 44.1 0.1 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain GMC_oxred_N PF00732.19 GAN00881.1 - 2.9e-51 174.6 0.6 2.8e-50 171.4 0.5 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAN00881.1 - 2.8e-23 83.0 0.2 3.3e-22 79.6 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAN00881.1 - 6.9e-12 45.2 1.4 1.2e-05 24.6 0.8 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAN00881.1 - 7.8e-08 31.9 0.4 0.0001 21.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN00881.1 - 8.1e-07 28.9 3.5 6.5e-06 26.0 4.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN00881.1 - 1e-05 25.6 0.9 3.5e-05 23.9 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAN00881.1 - 0.00014 21.2 0.1 0.00031 20.1 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAN00881.1 - 0.00082 18.2 0.8 0.0048 15.7 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAN00881.1 - 0.004 16.4 1.1 0.019 14.2 0.2 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 GAN00881.1 - 0.0072 15.6 0.0 0.53 9.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN00881.1 - 0.031 13.6 3.3 0.062 12.6 1.5 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAN00881.1 - 0.036 13.1 0.1 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein FliW PF02623.15 GAN00881.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 FliW protein GMC_oxred_N PF00732.19 GAN00882.1 - 5.7e-50 170.4 0.9 8e-50 169.9 0.2 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAN00882.1 - 5.7e-24 85.3 0.2 5.7e-24 85.3 0.2 1.8 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAN00882.1 - 5.8e-10 38.8 1.8 0.0002 20.6 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAN00882.1 - 1.2e-07 31.6 1.5 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN00882.1 - 4e-05 23.8 0.8 0.00034 20.8 0.9 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN00882.1 - 0.0014 17.9 0.1 0.0031 16.8 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN00882.1 - 0.0028 16.4 0.8 0.065 11.9 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GAN00882.1 - 0.017 14.4 1.1 0.059 12.6 1.1 1.9 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAN00882.1 - 0.07 12.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 GAN00882.1 - 0.076 13.5 0.0 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain DUF2795 PF11387.8 GAN00882.1 - 0.14 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) FAD_oxidored PF12831.7 GAN00882.1 - 0.16 11.3 0.8 0.32 10.3 0.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase SCIFF PF13165.6 GAN00882.1 - 0.43 10.6 3.5 1.3 9.0 3.5 1.8 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF GNAT_acetyltr_2 PF13718.6 GAN00883.1 - 6.3e-99 330.0 0.0 6.3e-99 330.0 0.0 2.3 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 GAN00883.1 - 2.5e-92 308.8 0.9 2.5e-92 308.8 0.9 1.8 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 GAN00883.1 - 6e-66 221.7 0.0 1.8e-65 220.1 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 GAN00883.1 - 1.8e-33 114.4 0.5 4.3e-33 113.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 GAN00883.1 - 0.007 16.6 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAN00883.1 - 0.018 15.4 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 GAN00883.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Acetyltransf_7 PF13508.7 GAN00883.1 - 0.11 13.0 0.0 0.76 10.2 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sas10_Utp3 PF04000.15 GAN00885.1 - 5.4e-13 49.4 1.9 5.4e-13 49.4 1.9 2.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Mito_carr PF00153.27 GAN00886.1 - 5.4e-68 225.0 0.8 1e-21 76.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN00886.1 - 0.00088 18.5 0.1 0.0049 16.1 0.0 2.2 3 0 0 3 3 3 1 Gammaproteobacterial serine protease PsaL PF02605.15 GAN00886.1 - 0.092 12.4 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI dUTPase PF00692.19 GAN00887.1 - 1.7e-42 144.2 0.0 1.9e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase RRM_1 PF00076.22 GAN00888.1 - 2.6e-27 94.5 0.0 6.5e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 GAN00888.1 - 5.4e-25 85.6 0.2 7.8e-07 28.4 0.1 4.4 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 GAN00888.1 - 9.9e-06 25.3 0.0 0.069 13.0 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GAN00888.1 - 0.00068 19.2 0.0 0.24 11.0 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nab6_mRNP_bdg PF10567.9 GAN00888.1 - 0.0011 18.5 0.2 0.018 14.6 0.0 2.5 3 0 0 3 3 3 1 RNA-recognition motif RRM_3 PF08777.11 GAN00888.1 - 0.0079 16.2 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif RRM_8 PF11835.8 GAN00888.1 - 0.14 12.4 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 RRM-like domain RNA_bind PF08675.11 GAN00888.1 - 0.16 12.0 0.0 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA binding domain Peroxin-13_N PF04088.13 GAN00889.1 - 1.6e-47 161.4 0.9 2.2e-47 161.0 0.9 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 GAN00889.1 - 6.6e-12 44.8 0.0 1.2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN00889.1 - 6.1e-11 41.8 0.0 1.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAN00889.1 - 9.4e-10 38.2 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PMG PF05287.12 GAN00889.1 - 0.00066 19.8 7.0 0.0011 19.0 7.0 1.3 1 0 0 1 1 1 1 PMG protein DUF3104 PF11302.8 GAN00889.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) HSP20 PF00011.21 GAN00890.1 - 6.4e-21 74.4 0.5 2.9e-13 49.8 0.2 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAN00890.1 - 8e-11 41.3 0.0 2e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA E1-E2_ATPase PF00122.20 GAN00891.1 - 7e-28 97.4 0.4 1.8e-27 96.0 0.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 GAN00891.1 - 7e-24 84.3 2.8 3.7e-23 82.0 2.8 2.4 1 0 0 1 1 1 1 P5-type ATPase cation transporter HSF_DNA-bind PF00447.17 GAN00891.1 - 2.1e-17 63.5 0.3 6.1e-17 62.0 0.3 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding Syntaxin-18_N PF10496.9 GAN00891.1 - 6.1e-16 58.4 1.8 6.1e-16 58.4 1.8 3.6 5 0 0 5 5 5 1 SNARE-complex protein Syntaxin-18 N-terminus Hydrolase PF00702.26 GAN00891.1 - 1.7e-09 38.3 0.1 0.025 14.9 0.0 3.6 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN00891.1 - 2e-05 24.6 0.0 9.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN00891.1 - 5.7e-05 22.7 0.4 0.00026 20.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus TFIIA PF03153.13 GAN00891.1 - 0.00064 19.8 12.8 0.00064 19.8 12.8 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SNARE PF05739.19 GAN00891.1 - 0.00095 19.1 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 SNARE domain KKLCAg1 PF15204.6 GAN00894.1 - 0.0097 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Kita-kyushu lung cancer antigen 1 NUDIX PF00293.28 GAN00895.1 - 4e-31 107.8 0.0 5.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CAP_GLY PF01302.25 GAN00897.1 - 4.4e-17 61.9 0.2 6.9e-17 61.2 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain HLH PF00010.26 GAN00898.1 - 2.7e-13 49.6 1.6 7.2e-13 48.3 1.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ins_allergen_rp PF06757.13 GAN00898.1 - 0.0011 18.9 0.1 0.0016 18.5 0.1 1.2 1 0 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification DUF4061 PF13270.6 GAN00898.1 - 0.046 14.0 0.6 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Glycogen_syn PF05693.13 GAN00898.1 - 0.088 11.3 0.5 0.11 11.1 0.5 1.0 1 0 0 1 1 1 0 Glycogen synthase Nnf1 PF03980.14 GAN00899.1 - 4.8e-10 39.8 3.9 4.8e-10 39.8 3.9 1.6 2 0 0 2 2 1 1 Nnf1 DUF2046 PF09755.9 GAN00899.1 - 0.0028 16.9 3.9 0.0044 16.3 3.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Prominin PF05478.11 GAN00899.1 - 0.018 13.1 2.5 0.022 12.7 2.5 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 GAN00899.1 - 0.023 14.1 2.0 0.03 13.7 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Dad2 PF08654.10 GAN00899.1 - 0.035 14.5 1.0 0.084 13.3 1.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad2 zf-CpG_bind_C PF12269.8 GAN00899.1 - 0.042 13.6 4.9 0.33 10.7 1.9 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain SpoVT_C PF15714.5 GAN00899.1 - 0.078 13.0 2.0 0.074 13.1 0.7 1.6 1 1 1 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor RPW8 PF05659.11 GAN00899.1 - 0.082 12.6 4.2 0.3 10.8 0.5 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 IclR PF01614.18 GAN00899.1 - 0.12 12.2 0.3 0.26 11.1 0.3 1.6 1 0 0 1 1 1 0 Bacterial transcriptional regulator DUF1943 PF09172.11 GAN00899.1 - 0.15 11.3 2.5 0.17 11.1 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Cauli_DNA-bind PF03310.13 GAN00899.1 - 0.58 10.2 4.7 5.3 7.1 0.2 2.5 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein DUF1664 PF07889.12 GAN00899.1 - 0.64 10.1 4.7 0.34 10.9 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 GAN00899.1 - 1.3 9.7 9.2 6 7.6 0.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA CI-B14_5a PF07347.12 GAN00900.1 - 0.00017 21.4 0.6 0.00057 19.7 0.3 1.9 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF3712 PF12505.8 GAN00901.1 - 9.1e-70 232.7 33.4 1.4e-23 83.5 0.7 7.5 6 2 0 7 7 7 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAN00901.1 - 3.6e-08 33.9 21.5 0.098 13.2 0.1 8.6 10 0 0 10 10 10 3 Late embryogenesis abundant protein RIFIN PF02009.16 GAN00901.1 - 0.22 11.3 7.1 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Rifin DUF1356 PF07092.12 GAN00901.1 - 0.84 8.9 4.7 6.8 5.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1356) DUF2407 PF10302.9 GAN00902.1 - 3.6e-05 24.3 0.1 0.00012 22.5 0.1 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAN00902.1 - 0.0028 17.4 0.0 0.0073 16.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 GAN00902.1 - 0.016 15.3 0.1 0.074 13.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like 2-oxoacid_dh PF00198.23 GAN00903.1 - 1.4e-82 276.7 0.0 1.7e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAN00903.1 - 4e-17 61.8 0.3 9.8e-17 60.6 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAN00903.1 - 4.5e-14 52.5 0.4 4.5e-14 52.5 0.4 2.1 2 0 0 2 2 2 1 e3 binding domain SspB PF04386.13 GAN00903.1 - 0.087 12.7 0.5 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Stringent starvation protein B GATA PF00320.27 GAN00904.1 - 8.4e-31 105.3 20.6 2.2e-15 56.0 5.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN00904.1 - 3.8e-06 26.3 7.3 0.0084 15.6 1.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 GAN00904.1 - 0.00022 21.3 1.4 0.56 10.4 0.2 2.9 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 GAN00904.1 - 0.00062 19.9 8.1 0.18 12.0 0.5 2.8 2 1 1 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 GAN00904.1 - 0.86 9.6 12.0 0.73 9.8 0.5 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 GAN00904.1 - 0.86 9.5 6.3 2.8 7.9 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Adaptin_binding PF10199.9 GAN00904.1 - 1.1 9.9 5.9 0.35 11.5 1.8 2.3 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 PQ-loop PF04193.14 GAN00906.1 - 2.1e-16 59.4 1.1 2.1e-16 59.4 1.1 2.7 3 1 1 4 4 4 1 PQ loop repeat ER_lumen_recept PF00810.18 GAN00906.1 - 0.00046 21.0 3.5 0.00046 21.0 3.5 2.2 1 1 1 2 2 2 1 ER lumen protein retaining receptor Thioredoxin_7 PF13899.6 GAN00907.1 - 1.4e-18 66.8 0.2 6.1e-18 64.8 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin-like UBX PF00789.20 GAN00907.1 - 2.7e-13 49.9 0.0 7.4e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 GAN00907.1 - 1e-11 44.4 0.1 3.3e-11 42.8 0.1 1.9 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 GAN00907.1 - 0.022 14.6 0.3 0.079 12.9 0.3 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.15 GAN00907.1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 GAN00907.1 - 0.16 12.4 0.0 0.49 10.9 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain TIM PF00121.18 GAN00908.1 - 2.1e-92 308.9 0.1 2.3e-92 308.7 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PilM PF07419.12 GAN00908.1 - 0.04 14.1 0.0 1.6 8.9 0.0 2.3 2 1 0 2 2 2 0 PilM F-box-like PF12937.7 GAN00909.1 - 1.6e-10 40.7 0.0 3.2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN00909.1 - 0.00024 20.9 0.0 0.00061 19.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain zf-C2H2 PF00096.26 GAN00910.1 - 5.3e-09 36.0 6.8 4.1e-05 23.8 1.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN00910.1 - 2.4e-07 30.9 1.4 2.4e-07 30.9 1.4 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAN00910.1 - 0.0039 17.2 1.9 0.0043 17.0 0.1 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAN00910.1 - 0.0053 17.5 6.1 0.94 10.5 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAN00910.1 - 0.014 15.7 1.6 0.014 15.7 1.6 2.8 3 1 1 4 4 4 0 C2H2-type zinc ribbon MCLC PF05934.11 GAN00910.1 - 0.18 10.5 1.1 0.23 10.1 1.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) MCM_bind PF09739.9 GAN00910.1 - 0.56 8.6 8.2 0.8 8.1 8.2 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Macoilin PF09726.9 GAN00910.1 - 1.2 7.6 10.9 1.3 7.5 10.9 1.1 1 0 0 1 1 1 0 Macoilin family FOXP-CC PF16159.5 GAN00910.1 - 1.4 9.6 8.1 0.49 11.1 0.3 3.0 1 1 2 3 3 3 0 FOXP coiled-coil domain ALMT PF11744.8 GAN00910.1 - 1.9 7.2 4.2 2.5 6.8 4.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Maf1 PF09174.10 GAN00911.1 - 1.3e-41 142.7 0.0 1.6e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator DUSP PF06337.12 GAN00912.1 - 2.7e-07 31.1 0.0 2.7e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 DUSP domain zf-UBP PF02148.19 GAN00912.1 - 7.8e-07 29.3 5.2 1.9e-06 28.1 5.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein F-box-like PF12937.7 GAN00912.1 - 1.1e-06 28.4 0.2 2.5e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN00912.1 - 0.02 14.8 1.3 0.047 13.6 0.6 2.0 2 0 0 2 2 2 0 F-box domain GREB1 PF15782.5 GAN00913.1 - 1.3 6.1 17.0 1.7 5.7 17.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mito_carr PF00153.27 GAN00914.1 - 3.7e-60 199.9 4.6 8.2e-21 73.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN00914.1 - 0.063 12.4 2.2 2.2 7.4 0.1 2.7 2 1 1 3 3 3 0 Gammaproteobacterial serine protease SRA1 PF07304.11 GAN00915.1 - 3.1e-15 56.2 0.0 4.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 GAN00915.1 - 8.3e-09 35.6 0.2 8.6e-08 32.3 0.3 1.9 1 1 1 2 2 2 1 Prp18 domain Peptidase_M24 PF00557.24 GAN00916.1 - 4.8e-52 176.7 0.1 6e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GAN00916.1 - 2.3e-18 66.2 10.6 5.7e-18 65.0 10.6 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GAN00916.1 - 0.00063 19.8 7.8 0.0015 18.6 7.8 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 GAN00916.1 - 0.64 9.9 5.0 1.6 8.7 5.0 1.7 1 0 0 1 1 1 0 HIT zinc finger TerY_C PF15616.6 GAN00916.1 - 1.6 8.9 6.3 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain DUF3759 PF12585.8 GAN00917.1 - 5.1e-36 122.6 6.0 5.9e-36 122.4 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2939 PF11159.8 GAN00917.1 - 0.079 13.4 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) UBX PF00789.20 GAN00918.1 - 1.2e-08 35.1 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain CCDC50_N PF15295.6 GAN00918.1 - 0.0049 17.0 0.7 0.0074 16.4 0.7 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus B277 PF17623.2 GAN00918.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Peptidase_C12 PF01088.21 GAN00919.1 - 1.2e-62 211.5 0.0 1.5e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 EB PF01683.18 GAN00920.1 - 0.0091 16.3 6.5 0.0091 16.3 6.5 2.6 2 1 0 2 2 2 1 EB module FxsA PF04186.13 GAN00920.1 - 0.12 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Dickkopf_N PF04706.12 GAN00920.1 - 8.5 6.9 16.9 0.079 13.5 8.7 1.8 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region CSG2 PF16965.5 GAN00921.1 - 0.26 10.2 3.0 0.4 9.6 3.0 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 GAN00921.1 - 0.33 10.1 8.2 0.48 9.6 8.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GAN00921.1 - 0.33 9.7 13.2 0.42 9.3 13.2 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GAN00921.1 - 0.97 8.1 15.2 1.2 7.9 15.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 GAN00921.1 - 1.2 7.5 4.9 1.7 7.0 4.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Myb_DNA-bind_6 PF13921.6 GAN00922.1 - 0.00066 19.9 1.2 0.0058 16.9 0.0 2.6 2 2 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN00922.1 - 0.0049 17.0 0.2 0.017 15.3 0.0 2.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF5572 PF17733.1 GAN00923.1 - 1e-20 73.3 1.8 1.8e-20 72.5 1.8 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) MFS_1 PF07690.16 GAN00924.1 - 1.7e-24 86.4 32.0 1.2e-17 63.9 3.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTCRA PF15028.6 GAN00924.1 - 0.17 11.6 0.1 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Pre-T-cell antigen receptor Pox_A14 PF05767.12 GAN00924.1 - 0.81 9.9 6.8 7.2 6.8 0.0 3.6 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 DUF3425 PF11905.8 GAN00926.1 - 8e-16 58.1 3.0 1.4e-15 57.4 0.9 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAN00926.1 - 5.6e-08 32.8 8.8 1.4e-07 31.5 8.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN00926.1 - 3.9 7.6 22.9 0.029 14.5 13.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Cu-oxidase PF00394.22 GAN00927.1 - 5.5e-35 120.8 0.0 2.8e-34 118.6 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAN00927.1 - 2.9e-30 104.7 0.8 1.7e-29 102.3 0.6 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAN00927.1 - 1.5e-18 66.8 17.2 2.6e-16 59.6 7.4 3.9 2 2 0 2 2 2 2 Multicopper oxidase ubiquitin PF00240.23 GAN00928.1 - 3.4e-24 84.4 0.0 3.9e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAN00928.1 - 5.6e-13 48.5 0.1 6.3e-13 48.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAN00928.1 - 3.3e-05 24.2 0.0 8.5e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAN00928.1 - 0.00012 22.0 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAN00928.1 - 0.1 12.7 0.1 16 5.6 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain AAA_23 PF13476.6 GAN00929.1 - 8.9e-33 114.5 0.2 8.9e-33 114.5 0.2 8.3 2 1 1 3 3 1 1 AAA domain AAA_15 PF13175.6 GAN00929.1 - 2.8e-15 56.9 0.0 8.6e-11 42.2 0.0 5.3 1 1 2 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 GAN00929.1 - 4.7e-08 33.2 7.2 0.00038 20.4 0.0 4.0 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 GAN00929.1 - 4.3e-06 26.5 2.9 8.9e-05 22.2 0.1 4.5 2 0 0 2 2 2 1 Rad50 zinc hook motif SMC_N PF02463.19 GAN00929.1 - 1.2e-05 24.9 35.7 0.00082 18.9 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 GAN00929.1 - 0.00021 21.5 0.0 0.00059 20.0 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAN00929.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1474 PF07342.11 GAN00929.1 - 0.13 12.8 2.8 0.31 11.6 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) ABC_tran PF00005.27 GAN00929.1 - 0.17 12.4 0.1 0.17 12.4 0.1 6.9 3 2 0 3 3 2 0 ABC transporter AAA_13 PF13166.6 GAN00929.1 - 0.2 10.3 0.0 0.2 10.3 0.0 7.2 2 1 4 7 7 7 0 AAA domain Atypical_Card PF18461.1 GAN00929.1 - 9.4 6.5 16.6 6.8 7.0 0.0 6.5 6 1 1 7 7 7 0 Atypical caspase recruitment domain NPV_P10 PF05531.12 GAN00929.1 - 9.5 6.8 55.2 0.11 13.0 6.8 9.3 7 3 2 9 9 9 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.29 GAN00930.1 - 1.4e-44 151.9 0.1 2.2e-44 151.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN00930.1 - 3.7e-27 94.9 2.6 8.7e-27 93.7 0.4 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN00930.1 - 2.2e-05 24.5 0.5 4.5e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAN00930.1 - 0.0058 16.2 1.3 0.09 12.3 0.1 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 GAN00930.1 - 0.037 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Histone_HNS PF00816.21 GAN00930.1 - 0.064 14.1 0.6 0.15 12.9 0.6 1.6 1 0 0 1 1 1 0 H-NS histone family Sirohm_synth_M PF14824.6 GAN00930.1 - 0.28 10.7 0.9 0.57 9.7 0.9 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central GRP PF07172.11 GAN00930.1 - 1.9 9.3 9.4 3.4 8.4 9.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family API5 PF05918.11 GAN00930.1 - 2.1 7.0 6.8 3.6 6.3 6.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SET PF00856.28 GAN00932.1 - 4.5e-09 36.9 0.1 3.5e-08 34.0 0.1 2.2 1 1 0 1 1 1 1 SET domain Cnd2 PF05786.14 GAN00932.1 - 3.6e-05 22.6 5.6 6.1e-05 21.9 3.3 1.9 2 0 0 2 2 2 1 Condensin complex subunit 2 Ribosomal_L37ae PF01780.19 GAN00932.1 - 0.086 12.9 1.2 0.18 11.9 0.7 1.8 2 0 0 2 2 2 0 Ribosomal L37ae protein family CDC48_2 PF02933.17 GAN00932.1 - 0.11 12.2 0.2 16 5.4 0.0 2.8 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 DNA_pol_phi PF04931.13 GAN00932.1 - 0.23 9.5 23.2 0.0087 14.2 13.7 2.1 2 0 0 2 2 2 0 DNA polymerase phi Cytochrom_c3_2 PF14537.6 GAN00932.1 - 0.24 11.9 5.4 0.33 11.5 0.5 2.6 2 0 0 2 2 2 0 Cytochrome c3 Cwf_Cwc_15 PF04889.12 GAN00932.1 - 8 6.1 28.8 2.6 7.7 17.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Dynactin_p62 PF05502.13 GAN00933.1 - 1.6e-55 188.8 0.7 3.6e-46 157.9 0.3 2.1 1 1 1 2 2 2 2 Dynactin p62 family PX PF00787.24 GAN00934.1 - 8.2e-09 35.4 1.9 1.7e-08 34.4 1.9 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 GAN00934.1 - 0.0025 17.7 0.1 0.021 14.7 0.0 2.5 3 0 0 3 3 3 1 PB1 domain Borrelia_orfA PF02414.15 GAN00934.1 - 0.0053 16.5 0.3 0.011 15.4 0.3 1.6 1 0 0 1 1 1 1 Borrelia ORF-A SF1-HH PF16275.5 GAN00934.1 - 0.063 13.6 5.5 0.1 12.9 1.6 2.4 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain RtxA PF07634.11 GAN00934.1 - 0.063 13.8 0.2 0.14 12.7 0.2 1.6 1 0 0 1 1 1 0 RtxA repeat Acyltransferase PF01553.21 GAN00936.1 - 8.5e-20 70.7 0.0 1.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase HSF_DNA-bind PF00447.17 GAN00937.1 - 1.2e-32 112.3 1.5 1.2e-32 112.3 1.5 3.2 3 1 0 3 3 3 1 HSF-type DNA-binding CDP-OH_P_transf PF01066.21 GAN00938.1 - 2.6e-13 50.5 0.2 2.6e-13 50.5 0.2 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DDE_3 PF13358.6 GAN00939.1 - 4.5e-10 39.4 0.0 4.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pribosyltran PF00156.27 GAN00940.1 - 5.9e-13 48.6 0.1 1.6e-12 47.2 0.0 1.7 1 1 1 2 2 2 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 GAN00940.1 - 0.051 13.1 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase ADH_zinc_N PF00107.26 GAN00941.1 - 1.7e-26 92.7 0.4 3.3e-26 91.8 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN00941.1 - 2.4e-18 67.5 0.0 4.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN00941.1 - 1.4e-09 37.8 0.0 1.8e-08 34.2 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Arg_repressor_C PF02863.18 GAN00941.1 - 0.017 15.0 3.1 2.2 8.2 0.5 2.5 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain MRG PF05712.13 GAN00942.1 - 2.6e-56 190.1 3.3 4.2e-56 189.4 3.3 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 GAN00942.1 - 5.6e-12 45.4 1.2 1.2e-11 44.4 1.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2713 PF10897.8 GAN00942.1 - 0.036 13.7 0.1 0.083 12.5 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2713) DUF684 PF05075.14 GAN00942.1 - 0.036 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Chromo PF00385.24 GAN00942.1 - 0.037 13.9 3.6 0.12 12.3 3.6 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain MMM1 PF10296.9 GAN00943.1 - 7.7e-05 21.9 1.0 0.00012 21.3 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 RED_N PF07808.13 GAN00943.1 - 0.022 14.3 0.4 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 RED-like protein N-terminal region Sel1 PF08238.12 GAN00944.1 - 2.2e-47 158.4 13.9 1.3e-07 32.0 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 GAN00944.1 - 0.029 15.0 2.2 21 6.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4679 PF15728.5 GAN00944.1 - 0.59 9.1 10.7 0.87 8.6 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) TPR_11 PF13414.6 GAN00944.1 - 3.7 7.3 7.8 20 5.0 0.1 4.1 4 0 0 4 4 4 0 TPR repeat Tmemb_14 PF03647.13 GAN00945.1 - 4.6e-22 78.6 15.7 4.1e-20 72.3 5.5 2.1 2 0 0 2 2 2 2 Transmembrane proteins 14C VIT1 PF01988.19 GAN00945.1 - 0.044 13.7 0.7 0.044 13.7 0.7 1.7 1 1 0 1 1 1 0 VIT family CPP1-like PF11833.8 GAN00945.1 - 0.075 12.7 2.2 0.073 12.7 1.0 1.5 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FUSC_2 PF13515.6 GAN00945.1 - 0.12 12.5 6.8 0.028 14.5 3.5 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein-like PAH PF02671.21 GAN00946.1 - 4.6e-12 45.9 0.2 1.2e-11 44.6 0.1 1.8 2 0 0 2 2 2 1 Paired amphipathic helix repeat DUF1768 PF08719.11 GAN00946.1 - 2.1e-08 34.6 0.1 5.9e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) Phage_Gp17 PF17549.2 GAN00946.1 - 0.058 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Gene Product 17 zf-RING_5 PF14634.6 GAN00947.1 - 6.4 6.8 9.1 0.23 11.5 3.1 1.8 2 0 0 2 2 2 0 zinc-RING finger domain START PF01852.19 GAN00948.1 - 7.1e-14 51.7 0.5 1.5e-13 50.6 0.3 1.5 2 0 0 2 2 2 1 START domain RabGAP-TBC PF00566.18 GAN00949.1 - 2.4e-27 96.0 1.8 2.4e-27 96.0 1.8 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ZapB PF06005.12 GAN00949.1 - 0.016 15.6 4.9 0.016 15.6 4.9 5.2 3 2 1 4 4 4 0 Cell division protein ZapB TSC22 PF01166.18 GAN00949.1 - 0.082 13.2 4.8 3.1 8.2 0.2 4.1 3 1 0 3 3 3 0 TSC-22/dip/bun family DASH_Dam1 PF08653.10 GAN00949.1 - 1.3 8.8 3.5 12 5.8 0.1 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 APG6_N PF17675.1 GAN00949.1 - 2.2 8.8 50.4 0.046 14.2 5.2 5.6 2 1 4 6 6 6 0 Apg6 coiled-coil region YabA PF06156.13 GAN00949.1 - 3.4 8.4 27.7 0.19 12.4 3.7 4.6 2 1 0 2 2 2 0 Initiation control protein YabA Velvet PF11754.8 GAN00950.1 - 2.9e-75 253.4 2.5 2.2e-45 155.6 0.1 2.2 1 1 1 2 2 2 2 Velvet factor Glyco_transf_49 PF13896.6 GAN00951.1 - 1e-31 110.5 0.3 3.1e-24 85.9 0.1 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan MRAP PF15183.6 GAN00951.1 - 0.14 12.1 0.7 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family CYSTM PF12734.7 GAN00952.1 - 0.00089 19.5 35.7 0.00089 19.5 35.7 3.5 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance IPP-2 PF04979.14 GAN00954.1 - 3.6e-18 66.6 16.0 3.6e-18 66.6 16.0 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) IpaC_SipC PF09599.10 GAN00954.1 - 0.48 9.9 4.7 0.088 12.3 0.8 1.6 2 0 0 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) TrkH PF02386.16 GAN00956.1 - 9.9e-93 311.3 7.4 1.8e-89 300.5 3.5 2.2 2 0 0 2 2 2 2 Cation transport protein PPR_2 PF13041.6 GAN00956.1 - 9.3e-10 38.6 0.0 0.0085 16.3 0.0 4.1 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 GAN00956.1 - 4e-05 23.6 0.1 0.15 12.1 0.0 3.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 GAN00956.1 - 8.8e-05 22.5 0.1 0.31 11.4 0.0 4.7 5 0 0 5 5 5 1 PPR repeat TPR_19 PF14559.6 GAN00956.1 - 0.066 13.7 0.6 0.45 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat YqzM PF14141.6 GAN00956.1 - 0.88 9.7 5.6 3.2 7.9 5.6 2.0 1 0 0 1 1 1 0 YqzM-like protein WD40 PF00400.32 GAN00957.1 - 1.1e-12 48.2 2.0 0.17 12.8 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat G-patch PF01585.23 GAN00958.1 - 1.5e-09 37.6 0.9 3.8e-09 36.3 0.9 1.7 1 0 0 1 1 1 1 G-patch domain Pex14_N PF04695.13 GAN00959.1 - 0.021 15.5 0.3 0.021 15.5 0.3 4.0 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 GAN00960.1 - 4.8e-19 68.4 22.4 1.8e-06 28.5 0.0 6.9 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN00960.1 - 2.5e-18 66.1 7.4 3.3e-07 30.5 0.1 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN00960.1 - 0.00042 20.2 2.8 0.0092 15.9 1.7 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN00960.1 - 0.044 12.8 0.1 0.13 11.2 0.0 1.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C2H2 PF00096.26 GAN00961.1 - 1.1e-07 32.0 4.1 0.011 16.1 0.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN00961.1 - 0.0041 17.8 5.6 1.4 10.0 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger TFIIA PF03153.13 GAN00961.1 - 0.16 11.9 20.9 0.21 11.5 20.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 GAN00961.1 - 1.3 7.6 5.8 1.3 7.6 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 GAN00961.1 - 4.5 5.9 5.3 5.7 5.6 5.3 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 GAN00963.1 - 1.4e-62 211.5 0.1 2.4e-37 128.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN00963.1 - 5.6e-40 137.2 0.1 5.7e-27 94.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN00963.1 - 0.0032 16.8 0.0 0.88 8.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 GAN00963.1 - 0.17 10.6 2.8 0.5 9.1 2.8 1.9 1 1 0 1 1 1 0 Fungal protein kinase PALP PF00291.25 GAN00964.1 - 8.2e-67 225.7 0.1 1.1e-66 225.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 GAN00964.1 - 3.1e-15 56.4 0.1 7e-07 29.6 0.0 3.8 3 1 1 4 4 4 2 CBS domain adh_short PF00106.25 GAN00964.1 - 0.052 13.0 0.2 2.1 7.8 0.0 2.7 3 0 0 3 3 3 0 short chain dehydrogenase Glyco_tran_WecB PF03808.13 GAN00964.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family ChAPs PF09295.10 GAN00965.1 - 7e-153 509.3 0.5 1.2e-149 498.7 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 GAN00965.1 - 1.7e-07 31.7 1.3 0.11 13.1 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAN00965.1 - 0.002 18.8 3.6 57 4.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAN00965.1 - 0.011 16.4 2.9 4.8 7.9 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat C4bp_oligo PF18453.1 GAN00965.1 - 0.03 14.5 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha TPR_2 PF07719.17 GAN00965.1 - 0.17 12.1 12.3 9.9 6.6 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN00965.1 - 0.21 11.9 12.2 2.9 8.3 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 GAN00967.1 - 7.8e-17 61.3 0.0 2.1e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAN00967.1 - 1.4e-09 38.2 0.2 1.8e-08 34.6 0.0 2.3 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 GAN00967.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Ribosomal_S10 PF00338.22 GAN00968.1 - 6.5e-29 100.1 0.5 9e-29 99.6 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2540 PF10802.8 GAN00968.1 - 0.041 13.9 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) MFS_1 PF07690.16 GAN00969.1 - 2e-35 122.4 36.3 1e-29 103.6 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN00969.1 - 2.4e-30 105.8 15.4 9.9e-24 84.0 0.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter DUF485 PF04341.12 GAN00969.1 - 7.6 6.6 10.7 1 9.4 0.4 3.5 3 1 0 3 3 3 0 Protein of unknown function, DUF485 DUF1279 PF06916.13 GAN00970.1 - 1.2e-18 67.4 0.3 1.5e-18 67.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2347 PF09804.9 GAN00971.1 - 2.1e-69 234.2 0.3 4.3e-69 233.2 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DAGK_cat PF00781.24 GAN00971.1 - 3e-29 101.2 0.0 6.3e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4484 PF14831.6 GAN00971.1 - 2e-09 37.8 4.3 8.1e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) SPA PF08616.10 GAN00971.1 - 4.5e-08 33.0 0.1 1.6e-07 31.2 0.1 2.0 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAN00971.1 - 4.1e-06 25.8 0.6 0.019 13.7 0.0 2.8 2 1 1 3 3 3 2 Transport protein Avl9 Afi1 PF07792.12 GAN00971.1 - 0.055 13.9 0.3 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Med31 PF05669.12 GAN00973.1 - 2.8e-36 123.4 13.7 3.4e-36 123.1 13.7 1.1 1 0 0 1 1 1 1 SOH1 HAD_2 PF13419.6 GAN00973.1 - 0.029 14.5 0.1 0.034 14.2 0.1 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Rit1_C PF17184.4 GAN00975.1 - 7.8e-96 320.7 0.0 1.1e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 GAN00975.1 - 1.5e-12 47.8 0.0 3.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain DSPc PF00782.20 GAN00975.1 - 1.8e-08 34.2 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Methyltransf_10 PF05971.12 GAN00976.1 - 4.9e-78 262.5 0.1 8.5e-78 261.7 0.0 1.4 2 0 0 2 2 2 1 RNA methyltransferase MTS PF05175.14 GAN00976.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAN00976.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 GAN00976.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TPR_19 PF14559.6 GAN00977.1 - 2.3e-13 50.4 1.3 3.9e-08 33.7 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN00977.1 - 2.9e-08 33.9 3.0 0.0024 18.1 0.3 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAN00977.1 - 7.7e-08 32.5 0.6 0.81 10.5 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAN00977.1 - 3e-07 30.0 0.0 2 8.7 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN00977.1 - 7.3e-07 29.5 0.3 0.21 12.5 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN00977.1 - 1.8e-06 28.0 0.0 0.0027 17.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN00977.1 - 3.2e-06 27.3 0.2 0.0026 17.9 0.1 2.8 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GAN00977.1 - 2.1e-05 24.1 0.1 2 8.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAN00977.1 - 0.00011 22.5 0.1 0.12 13.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 GAN00977.1 - 0.00018 21.3 2.3 0.0011 18.7 2.2 2.7 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 GAN00977.1 - 0.00022 21.0 0.3 0.96 9.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAN00977.1 - 0.00048 19.9 1.7 2.1 8.3 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN00977.1 - 0.0013 18.8 0.1 0.19 12.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN00977.1 - 0.0028 17.9 2.2 4.8 7.8 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 GAN00977.1 - 0.0035 16.8 0.6 0.0035 16.8 0.6 1.9 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_MalT PF17874.1 GAN00977.1 - 0.0077 15.6 4.1 0.0086 15.5 1.4 2.2 1 1 1 2 2 2 1 MalT-like TPR region PPR PF01535.20 GAN00977.1 - 0.016 15.4 0.6 0.32 11.3 0.3 3.0 3 0 0 3 3 3 0 PPR repeat HrpB1_HrpK PF09613.10 GAN00977.1 - 0.041 13.5 0.7 1.2 8.8 0.1 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 GAN00977.1 - 0.046 14.4 0.0 3.6 8.3 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat CHCH PF06747.13 GAN00979.1 - 7.5e-05 22.8 7.1 0.00014 21.8 7.1 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 GAN00979.1 - 0.0073 16.3 1.3 0.089 12.8 0.2 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RasGEF PF00617.19 GAN00980.1 - 8.4e-51 172.7 0.7 2.1e-50 171.4 0.7 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN00980.1 - 1.8e-15 57.0 6.4 2.4e-15 56.6 4.5 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif TolA_bind_tri PF16331.5 GAN00980.1 - 0.0091 16.1 3.1 2 8.6 0.5 3.3 3 0 0 3 3 3 2 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 GAN00980.1 - 0.054 13.9 0.1 0.24 11.9 0.1 2.1 1 0 0 1 1 1 0 Snapin/Pallidin JHD PF17811.1 GAN00980.1 - 0.065 13.8 0.3 2.6 8.6 0.1 2.9 2 0 0 2 2 2 0 Jumonji helical domain Pex24p PF06398.11 GAN00981.1 - 1.4e-12 47.3 2.3 1.8e-12 46.9 2.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.6 GAN00981.1 - 0.017 15.4 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Tom37 PF10568.9 GAN00982.1 - 4.9e-36 123.8 0.7 7.9e-36 123.1 0.7 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 GAN00982.1 - 4.9e-20 72.1 0.1 8.7e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAN00982.1 - 1.8e-17 62.9 0.6 6.6e-17 61.1 0.1 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN00982.1 - 0.00015 21.7 0.0 0.00084 19.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN00982.1 - 0.0093 16.2 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAN00982.1 - 0.013 15.6 0.0 0.047 13.9 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IP_trans PF02121.18 GAN00983.1 - 6.6e-100 333.7 2.9 7.5e-100 333.6 2.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Plk4_PB1 PF18190.1 GAN00983.1 - 0.08 13.1 0.6 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 DUF4396 PF14342.6 GAN00984.1 - 5.7e-44 149.9 5.0 7.4e-44 149.5 5.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Polysacc_synt_C PF14667.6 GAN00984.1 - 0.098 12.7 3.8 4.7 7.3 0.1 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain COX6A PF02046.15 GAN00986.1 - 3.5e-29 101.6 0.8 3.9e-29 101.4 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa S-layer PF07752.11 GAN00986.1 - 0.0062 15.6 0.1 0.012 14.7 0.1 1.4 1 1 1 2 2 2 1 S-layer protein Tetraspanin PF00335.20 GAN00987.1 - 4.3e-05 23.3 9.2 0.00012 21.9 9.2 1.7 1 1 0 1 1 1 1 Tetraspanin family UPF0239 PF06783.11 GAN00987.1 - 0.0023 18.1 0.8 2.8 8.2 0.0 2.5 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0239) WBP-1 PF11669.8 GAN00987.1 - 0.018 15.7 0.2 1.5 9.5 0.0 2.6 2 1 0 2 2 2 0 WW domain-binding protein 1 DUF4191 PF13829.6 GAN00987.1 - 0.5 9.7 4.8 0.25 10.6 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) 2TM PF13239.6 GAN00987.1 - 2.8 8.3 7.5 24 5.3 0.1 2.4 2 0 0 2 2 2 0 2TM domain WD40 PF00400.32 GAN00988.1 - 2.8e-57 189.4 14.9 1.9e-08 34.8 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 GAN00988.1 - 2.2e-27 95.1 8.3 3.5e-27 94.5 8.3 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 GAN00988.1 - 1.3e-20 73.5 0.0 0.00078 19.7 0.0 6.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN00988.1 - 4.3e-11 42.3 0.1 0.02 13.9 0.0 5.1 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAN00988.1 - 2.6e-08 33.6 0.0 0.044 13.1 0.0 4.1 5 0 0 5 5 5 2 WD40-like domain PD40 PF07676.12 GAN00988.1 - 2.1e-05 24.3 0.2 7.2 6.7 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GAN00988.1 - 0.00017 20.2 0.1 0.0021 16.7 0.1 2.5 1 1 2 3 3 3 1 Cytochrome D1 heme domain eIF2A PF08662.11 GAN00988.1 - 0.00022 21.2 0.0 0.49 10.2 0.0 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAN00988.1 - 0.00051 19.5 0.1 4.1 6.7 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Golgin_A5 PF09787.9 GAN00988.1 - 0.0022 17.5 3.6 0.0038 16.7 3.6 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Spc7 PF08317.11 GAN00988.1 - 0.0029 16.5 3.1 0.0044 15.9 3.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Nup160 PF11715.8 GAN00988.1 - 0.0031 16.2 0.5 2.4 6.7 0.0 4.3 2 1 3 5 5 5 1 Nucleoporin Nup120/160 DUF724 PF05266.14 GAN00988.1 - 0.014 15.2 2.4 0.022 14.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF5122 PF17164.4 GAN00988.1 - 0.046 14.0 0.3 50 4.3 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Jnk-SapK_ap_N PF09744.9 GAN00988.1 - 0.067 13.4 5.5 0.12 12.6 5.5 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 GAN00988.1 - 0.068 13.2 5.7 0.33 11.0 6.1 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein RasGAP_C PF03836.15 GAN00988.1 - 0.083 13.0 4.9 0.15 12.2 4.9 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Dna2 PF08696.11 GAN00988.1 - 0.089 12.6 0.7 0.16 11.7 0.7 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 VID27 PF08553.10 GAN00988.1 - 0.14 11.2 0.0 12 4.8 0.0 2.8 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain DUF1640 PF07798.11 GAN00988.1 - 1.4 8.9 4.2 2.5 8.1 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3450 PF11932.8 GAN00988.1 - 2 7.7 7.2 4.2 6.6 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Proteasome_A_N PF10584.9 GAN00988.1 - 5.4 6.8 6.5 9.1 6.1 0.0 4.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CP2 PF04516.15 GAN00989.1 - 9.7e-53 178.8 0.3 2.6e-52 177.4 0.3 1.6 1 1 0 1 1 1 1 CP2 transcription factor Mucin_bdg PF03272.13 GAN00989.1 - 0.095 12.7 0.6 4.1 7.5 0.1 2.5 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module ATP-synt_ab_N PF02874.23 GAN00990.1 - 5.2e-24 84.6 1.7 1.1e-23 83.5 1.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 GAN00990.1 - 7.6e-19 68.2 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 GAN00990.1 - 0.0047 16.1 0.1 0.0065 15.7 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 GAN00990.1 - 0.0086 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 GAN00990.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 GAN00990.1 - 0.018 14.4 0.2 0.027 13.8 0.2 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 GAN00990.1 - 0.025 15.0 0.2 0.055 13.9 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 GAN00990.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAN00990.1 - 0.06 13.7 0.5 0.12 12.6 0.2 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAN00990.1 - 0.087 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 GAN00990.1 - 0.13 11.1 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 GAN00990.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAN00990.1 - 0.15 12.6 0.2 0.36 11.4 0.2 1.6 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 GAN00990.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_DE_N PF02823.16 GAN00991.1 - 2.7e-17 62.4 0.2 4e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain FAD_binding_3 PF01494.19 GAN00992.1 - 5.9e-64 216.5 0.0 3.5e-63 214.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAN00992.1 - 0.00025 20.5 0.1 0.00037 20.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 GAN00992.1 - 0.00041 20.0 0.1 0.014 15.0 0.0 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAN00992.1 - 0.0013 17.5 0.1 0.005 15.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAN00992.1 - 0.021 15.4 0.0 8.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAN00992.1 - 0.032 13.5 0.1 0.16 11.1 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAN00992.1 - 0.039 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GAN00992.1 - 0.19 11.0 0.0 0.42 9.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DHFR_1 PF00186.19 GAN00993.1 - 8.2e-28 97.1 0.0 2.9e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Dihydrofolate reductase Adaptin_N PF01602.20 GAN00994.1 - 1.9e-106 356.7 8.5 2.8e-106 356.2 8.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 GAN00994.1 - 1e-61 206.6 0.0 2.6e-61 205.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 GAN00994.1 - 1.8e-57 193.2 0.6 1.8e-57 193.2 0.6 2.1 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 GAN00994.1 - 9.3e-11 42.0 3.4 0.00032 21.0 0.0 5.1 1 1 4 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAN00994.1 - 1.1e-08 35.3 7.5 1.7e-05 24.9 0.0 3.8 1 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAN00994.1 - 5.7e-06 26.2 1.3 0.019 15.2 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 GAN00994.1 - 0.00023 21.3 0.0 0.001 19.2 0.0 2.2 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF5578 PF17741.1 GAN00994.1 - 0.00033 20.1 3.6 0.034 13.6 1.3 2.9 2 1 1 3 3 3 2 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 GAN00994.1 - 0.0006 20.3 0.5 0.3 11.6 0.0 4.1 4 0 0 4 4 4 1 HEAT-like repeat DUF5071 PF16804.5 GAN00994.1 - 0.0024 18.1 0.7 0.11 12.7 0.0 3.1 1 1 2 3 3 3 1 Domain of unknown function (DUF5071) BDV_G PF06208.11 GAN00994.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Borna disease virus G protein DUF1168 PF06658.12 GAN00996.1 - 4.1e-40 136.7 15.9 4.1e-40 136.7 15.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) DUF4407 PF14362.6 GAN00996.1 - 8.6 5.6 10.2 11 5.3 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DIL PF01843.19 GAN00997.1 - 1.1e-27 96.4 2.8 3.6e-27 94.7 2.8 2.0 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 GAN00997.1 - 1.2e-14 54.6 0.1 2.8e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN00997.1 - 6.2e-11 42.6 0.6 3.8e-06 27.3 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAN00997.1 - 6.9e-10 38.9 0.2 0.00017 21.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAN00997.1 - 6e-09 36.0 0.1 0.00014 22.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN00997.1 - 1.2e-07 31.4 0.7 0.0016 18.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Laps PF10169.9 GAN00997.1 - 0.11 13.1 7.8 0.43 11.2 7.8 2.0 1 0 0 1 1 1 0 Learning-associated protein Sel1 PF08238.12 GAN00998.1 - 8.4e-18 64.4 28.8 8e-06 26.4 0.4 8.4 8 0 0 8 8 8 4 Sel1 repeat TPR_1 PF00515.28 GAN00998.1 - 3.2e-06 26.7 7.3 7.3e-05 22.4 0.5 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN00998.1 - 0.00036 20.3 0.2 0.0033 17.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN00998.1 - 0.00043 20.2 0.7 0.00043 20.2 0.7 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN00998.1 - 0.012 16.4 0.1 0.38 11.7 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN00998.1 - 0.25 11.6 6.2 0.2 11.9 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN00998.1 - 1.5 9.6 5.1 4.1 8.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 GAN00999.1 - 4e-26 91.4 1.6 5.8e-15 55.6 0.4 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN00999.1 - 1.2e-24 86.3 2.6 1.1e-11 45.0 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN00999.1 - 2.7e-23 81.7 1.7 3.2e-08 33.7 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) FYVE PF01363.21 GAN00999.1 - 4.1e-18 65.3 9.2 7.6e-18 64.4 9.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 GAN00999.1 - 4.6e-18 63.4 1.3 0.00059 20.1 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAN00999.1 - 4.5e-17 61.7 0.4 0.0024 18.2 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat MIT PF04212.18 GAN00999.1 - 0.0038 17.3 2.8 0.0045 17.0 0.4 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain HATPase_c_5 PF14501.6 GAN00999.1 - 0.062 13.2 0.5 0.17 11.8 0.5 1.7 1 0 0 1 1 1 0 GHKL domain Talin_middle PF09141.10 GAN00999.1 - 0.07 13.2 0.4 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 Talin, middle domain C1_2 PF03107.16 GAN00999.1 - 0.16 12.3 6.4 0.52 10.7 6.4 1.9 1 0 0 1 1 1 0 C1 domain CAML PF14963.6 GAN00999.1 - 0.41 10.7 4.5 0.75 9.9 4.5 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand ANF_receptor PF01094.28 GAN01001.1 - 4.3e-40 137.9 0.3 1e-39 136.7 0.1 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region 7tm_3 PF00003.22 GAN01001.1 - 2e-30 106.3 34.6 2e-30 106.3 34.6 1.6 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 GAN01001.1 - 1.5e-17 64.3 0.0 2.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein PH_9 PF15410.6 GAN01001.1 - 0.024 15.0 1.0 0.054 13.9 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Ctr PF04145.15 GAN01002.1 - 5.9e-36 124.3 3.7 7e-36 124.1 3.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1286 PF06939.11 GAN01002.1 - 0.032 14.5 0.8 0.032 14.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) VEGFR-2_TMD PF17988.1 GAN01002.1 - 0.1 12.0 2.2 0.28 10.6 2.2 1.7 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Metallophos PF00149.28 GAN01002.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase CPBP PF02517.16 GAN01002.1 - 1.7 9.1 6.7 5.9 7.3 0.5 2.1 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Mannosyl_trans2 PF04188.13 GAN01003.1 - 5.9e-80 269.7 30.8 7.2e-80 269.5 30.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PPR_2 PF13041.6 GAN01006.1 - 2e-34 117.6 8.6 5.5e-09 36.1 0.0 7.1 5 3 3 8 8 8 6 PPR repeat family PPR_3 PF13812.6 GAN01006.1 - 1.8e-16 59.9 14.6 0.00036 20.6 0.1 6.4 4 2 3 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAN01006.1 - 4.9e-16 58.1 5.4 6.4e-05 22.6 0.0 6.9 7 0 0 7 7 7 4 PPR repeat PPR PF01535.20 GAN01006.1 - 7.2e-07 29.0 11.7 0.00049 20.1 0.0 7.7 9 1 0 9 9 9 1 PPR repeat PPR_long PF17177.4 GAN01006.1 - 2.1e-06 27.3 1.9 0.17 11.2 0.0 4.7 3 2 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAN01006.1 - 2.4e-05 24.7 5.9 0.063 13.7 0.6 3.9 3 1 0 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 GAN01006.1 - 0.0014 19.1 0.4 0.7 10.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN01006.1 - 0.015 15.5 0.1 1.2 9.4 0.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ca_bind_SSO6904 PF18249.1 GAN01006.1 - 0.029 14.7 2.2 0.045 14.1 0.5 2.1 2 0 0 2 2 2 0 Calcium binding protein SSO6904 AAA_25 PF13481.6 GAN01007.1 - 3.3e-22 79.0 0.0 7e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAN01007.1 - 1.1e-11 44.6 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAN01007.1 - 4.6e-08 33.4 0.0 1.3e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Toprim_4 PF13662.6 GAN01007.1 - 6.5e-06 26.5 0.0 0.0048 17.3 0.0 2.6 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.6 GAN01007.1 - 6.5e-05 23.3 0.0 0.00019 21.8 0.0 1.8 1 0 0 1 1 1 1 Toprim-like AAA_16 PF13191.6 GAN01007.1 - 0.00017 22.0 0.0 0.00041 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 GAN01007.1 - 0.00095 18.6 0.0 0.0027 17.1 0.0 1.8 1 1 0 1 1 1 1 KaiC ABC_tran PF00005.27 GAN01007.1 - 0.0018 18.8 0.0 0.0051 17.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 GAN01007.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_23 PF13476.6 GAN01007.1 - 0.0038 17.7 0.8 0.0038 17.7 0.8 2.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAN01007.1 - 0.0063 16.2 0.3 0.016 15.0 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Toprim_3 PF13362.6 GAN01007.1 - 0.014 15.8 0.1 0.37 11.2 0.0 2.8 3 0 0 3 3 2 0 Toprim domain AAA_30 PF13604.6 GAN01007.1 - 0.021 14.6 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAN01007.1 - 0.028 14.3 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 GAN01007.1 - 0.034 14.4 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAN01007.1 - 0.058 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 GAN01007.1 - 0.067 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 GAN01007.1 - 0.083 13.4 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAN01007.1 - 0.1 12.7 0.1 0.65 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 GAN01007.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_7 PF12775.7 GAN01007.1 - 0.14 11.6 0.6 0.38 10.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 GAN01007.1 - 0.15 11.7 0.1 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zn_Tnp_IS1595 PF12760.7 GAN01007.1 - 0.15 12.0 1.6 0.33 11.0 1.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NTPase_1 PF03266.15 GAN01007.1 - 0.17 11.8 1.3 0.24 11.3 0.2 1.8 2 0 0 2 2 2 0 NTPase HTH_9 PF08221.11 GAN01008.1 - 6.4e-26 90.2 2.0 2.7e-14 53.0 0.2 4.6 5 0 0 5 5 5 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 GAN01008.1 - 3.1e-20 73.0 0.4 5.4e-19 69.0 0.2 2.4 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 GAN01008.1 - 5.8e-12 45.4 0.1 7.3e-05 22.6 0.0 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.19 GAN01008.1 - 0.11 12.4 0.1 11 6.0 0.0 3.0 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB PALP PF00291.25 GAN01009.1 - 3e-68 230.4 1.9 3.6e-68 230.1 1.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IF-2B PF01008.17 GAN01009.1 - 0.019 14.2 0.2 0.17 11.0 0.2 2.2 2 0 0 2 2 2 0 Initiation factor 2 subunit family Transglut_core PF01841.19 GAN01009.1 - 0.14 12.7 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_transf_64 PF09258.10 GAN01011.1 - 7.9e-39 133.4 0.5 1.3e-38 132.7 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 GAN01011.1 - 8.1e-20 71.5 10.7 6.6e-11 42.3 0.4 2.6 2 1 1 3 3 3 2 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 GAN01011.1 - 0.003 17.6 0.4 0.0089 16.0 0.4 1.9 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 GAN01011.1 - 0.0033 16.8 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Neur_chan_memb PF02932.16 GAN01013.1 - 1.4 9.0 11.1 2 8.4 11.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 GAN01013.1 - 1.7 8.4 11.3 2.3 8.0 11.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 B12D PF06522.11 GAN01014.1 - 4.6e-18 64.8 0.0 5.6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Mito_carr PF00153.27 GAN01014.1 - 0.17 11.8 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial carrier protein Ribosomal_L28e PF01778.17 GAN01015.1 - 3.5e-33 114.8 5.7 4.4e-33 114.4 5.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family YjbT PF17089.5 GAN01015.1 - 0.036 14.1 0.2 0.3 11.1 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family DUF2500 PF10694.9 GAN01015.1 - 0.91 10.1 4.2 1.9 9.0 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) PGAP1 PF07819.13 GAN01016.1 - 2.8e-84 282.4 0.3 4.3e-84 281.8 0.3 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAN01016.1 - 2.2e-05 25.2 0.0 6.2e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 GAN01016.1 - 0.0003 20.7 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 GAN01016.1 - 0.0024 17.5 0.1 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 GAN01016.1 - 0.0095 15.5 0.6 0.023 14.2 0.6 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAN01016.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 GAN01016.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2970 PF11174.8 GAN01016.1 - 0.028 14.2 3.3 4.6 7.2 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF915 PF06028.11 GAN01016.1 - 0.056 12.8 0.0 0.91 8.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 GAN01016.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) ISG65-75 PF11727.8 GAN01018.1 - 0.0054 16.0 6.2 0.0054 16.0 6.2 1.6 1 1 0 1 1 1 1 Invariant surface glycoprotein AAA_lid_5 PF17865.1 GAN01018.1 - 0.075 13.1 0.9 0.23 11.5 0.6 2.0 1 1 0 1 1 1 0 Midasin AAA lid domain CLP_protease PF00574.23 GAN01018.1 - 0.095 12.6 0.5 0.095 12.6 0.5 2.0 2 0 0 2 2 2 0 Clp protease Helicase_RecD PF05127.14 GAN01018.1 - 0.57 10.0 7.2 0.31 10.9 2.5 2.6 1 1 1 2 2 2 0 Helicase Ribosomal_L11 PF00298.19 GAN01019.1 - 1.1e-29 102.7 0.7 2.1e-29 101.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAN01019.1 - 1.1e-24 86.0 0.4 1.7e-24 85.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Cytidylate_kin PF02224.18 GAN01021.1 - 0.15 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase PPR_2 PF13041.6 GAN01022.1 - 3.2e-46 155.3 6.3 2.8e-12 46.6 0.0 8.3 4 1 4 8 8 8 6 PPR repeat family PPR_3 PF13812.6 GAN01022.1 - 3.1e-38 129.7 1.0 4.3e-09 36.3 0.0 6.6 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAN01022.1 - 1.1e-33 114.6 4.8 4.7e-07 29.4 0.0 8.5 9 1 0 9 9 9 5 PPR repeat PPR PF01535.20 GAN01022.1 - 1.6e-32 109.4 11.3 3.8e-05 23.6 0.0 10.0 10 1 0 10 10 10 6 PPR repeat PPR_long PF17177.4 GAN01022.1 - 1.4e-19 70.3 6.9 1.3e-08 34.5 0.1 4.4 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 GAN01022.1 - 0.0012 18.7 5.5 3.2 7.6 0.0 5.5 2 1 4 6 6 6 2 Mitochondrial ATPase expression Phlebovirus_NSM PF07246.11 GAN01022.1 - 0.0054 16.2 0.1 0.0054 16.2 0.1 1.8 2 0 0 2 2 2 1 Phlebovirus nonstructural protein NS-M TPR_7 PF13176.6 GAN01022.1 - 0.036 14.1 0.1 6 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN01022.1 - 0.082 13.8 0.1 11 7.1 0.0 4.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2408 PF10303.9 GAN01023.1 - 0.00012 22.6 0.4 0.00016 22.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) CZB PF13682.6 GAN01023.1 - 0.0097 16.3 1.2 0.12 12.8 0.3 2.3 2 1 0 2 2 2 1 Chemoreceptor zinc-binding domain MobC PF05713.11 GAN01023.1 - 0.01 16.3 0.4 5.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) Rx_N PF18052.1 GAN01023.1 - 0.048 13.9 0.4 0.79 10.0 0.1 2.2 2 1 0 2 2 2 0 Rx N-terminal domain ROKNT PF08067.11 GAN01023.1 - 0.13 12.6 1.1 0.23 11.8 0.5 1.7 1 1 1 2 2 2 0 ROKNT (NUC014) domain Hemerythrin PF01814.23 GAN01023.1 - 0.17 12.5 2.1 1 10.0 2.1 1.9 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain SNARE_assoc PF09335.11 GAN01024.1 - 9.6e-12 45.4 1.0 9.6e-12 45.4 1.0 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2905 PF11146.8 GAN01024.1 - 0.061 13.5 0.5 0.69 10.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) Med14 PF08638.11 GAN01025.1 - 1e-58 197.9 1.7 5.5e-58 195.6 2.4 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 DHHC PF01529.20 GAN01026.1 - 8.8e-37 126.2 8.5 8.8e-37 126.2 8.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-ribbon_3 PF13248.6 GAN01026.1 - 0.23 10.9 4.9 0.63 9.5 4.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF3377 PF11857.8 GAN01026.1 - 2.9 7.9 4.4 7.7 6.5 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Tim17 PF02466.19 GAN01027.1 - 1.6e-25 89.6 8.2 2.8e-25 88.8 8.2 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Arrestin_C PF02752.22 GAN01028.1 - 3.1e-10 40.6 1.1 7.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN01028.1 - 2.9e-07 30.7 0.1 5.8e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain UQ_con PF00179.26 GAN01029.1 - 6.1e-48 162.0 0.0 7.6e-48 161.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CRC_subunit PF08624.10 GAN01030.1 - 2.7e-38 131.5 1.5 4e-34 118.0 0.3 2.6 2 1 1 3 3 3 2 Chromatin remodelling complex Rsc7/Swp82 subunit RFX5_DNA_bdg PF14621.6 GAN01030.1 - 2.2 8.0 6.3 0.11 12.2 0.5 1.8 2 0 0 2 2 2 0 RFX5 DNA-binding domain Ribosomal_S27 PF01599.19 GAN01031.1 - 2.9e-27 94.5 2.5 5.3e-27 93.7 2.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 GAN01031.1 - 5e-14 51.8 0.0 9.4e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAN01031.1 - 0.00017 21.4 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 GAN01031.1 - 0.012 15.8 0.3 0.02 15.1 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 GAN01031.1 - 0.023 14.7 0.1 0.7 10.0 0.1 2.5 1 1 1 2 2 2 0 Ubiquitin-like domain PET117 PF15786.5 GAN01032.1 - 1.3e-23 83.1 1.9 1.4e-23 82.9 1.9 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial SieB PF14163.6 GAN01032.1 - 0.049 13.1 0.1 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B Rho_Binding PF08912.11 GAN01032.1 - 0.11 13.3 8.5 0.16 12.8 8.5 1.1 1 0 0 1 1 1 0 Rho Binding E1_DerP2_DerF2 PF02221.15 GAN01034.1 - 4.5e-10 40.1 0.1 5.7e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 ML domain zf-H2C2_2 PF13465.6 GAN01035.1 - 4.4e-23 80.6 23.3 9.4e-08 32.2 0.3 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 GAN01035.1 - 4.6e-22 77.2 30.9 4.6e-06 26.8 1.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN01035.1 - 8.3e-11 41.8 28.2 0.0019 18.9 1.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN01035.1 - 8e-07 29.2 0.7 2.8 8.3 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 GAN01035.1 - 9.3e-06 26.2 10.7 0.2 12.3 0.2 4.1 2 1 2 4 4 4 3 FOXP coiled-coil domain zf-met PF12874.7 GAN01035.1 - 0.00023 21.4 5.4 8.4 6.9 0.1 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 GAN01035.1 - 0.00057 19.6 12.6 0.023 14.4 0.5 4.7 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-TRAF PF02176.18 GAN01035.1 - 0.048 14.4 9.1 0.58 10.9 0.4 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger Zn-C2H2_12 PF18112.1 GAN01035.1 - 0.07 13.6 1.3 4.3 7.9 0.0 3.5 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 GAN01035.1 - 0.35 10.7 18.9 1.3 8.9 0.8 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 GAN01035.1 - 0.54 10.3 14.1 12 6.0 1.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger PRCC PF10253.9 GAN01035.1 - 0.69 10.7 7.2 0.94 10.2 7.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting zf-LYAR PF08790.11 GAN01035.1 - 1.5 8.8 13.9 0.97 9.4 1.6 4.1 4 1 0 4 4 4 0 LYAR-type C2HC zinc finger CCAP PF11105.8 GAN01035.1 - 3 7.8 6.4 0.85 9.6 1.1 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-C2H2_aberr PF17017.5 GAN01035.1 - 6.6 6.9 8.2 36 4.4 0.3 3.6 1 1 2 4 4 4 0 Aberrant zinc-finger PEMT PF04191.13 GAN01037.1 - 2.5e-52 175.7 18.4 5e-33 113.7 0.6 3.5 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 GAN01037.1 - 1.7e-05 24.6 0.1 7.2e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 GAN01037.1 - 0.00011 22.6 0.0 0.00074 20.0 0.0 2.3 1 1 0 1 1 1 1 SKICH domain Apolipoprotein PF01442.18 GAN01037.1 - 0.059 13.2 3.9 0.1 12.5 1.3 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 GAN01037.1 - 0.063 13.4 2.0 0.12 12.4 2.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 GAN01037.1 - 0.075 13.3 1.2 0.29 11.4 1.2 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 GAN01037.1 - 0.15 12.1 3.4 0.21 11.6 2.2 1.8 2 0 0 2 2 2 0 Laminin Domain II EspB PF05802.11 GAN01037.1 - 0.16 11.9 1.2 0.27 11.2 1.2 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein LacI PF00356.21 GAN01037.1 - 0.56 10.0 2.3 1.6 8.5 1.5 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF883 PF05957.13 GAN01037.1 - 0.87 10.2 3.5 0.51 11.0 0.8 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribophorin_I PF04597.14 GAN01038.1 - 1.4e-126 423.3 5.1 2e-126 422.7 5.1 1.3 1 0 0 1 1 1 1 Ribophorin I zf-BED PF02892.15 GAN01038.1 - 0.21 11.6 1.1 2 8.5 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger VIT1 PF01988.19 GAN01039.1 - 9.1e-72 241.4 0.0 1.2e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 VIT family Phosphoesterase PF04185.14 GAN01040.1 - 1.5e-87 294.1 2.2 2e-87 293.7 2.2 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 GAN01040.1 - 0.0014 19.3 2.9 1.7 9.4 0.2 3.4 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Amino_oxidase PF01593.24 GAN01041.1 - 9.9e-22 77.8 0.0 1.1e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAN01041.1 - 1.4e-10 41.2 0.1 3.4e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAN01041.1 - 4.1e-06 26.2 0.1 2e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAN01041.1 - 5e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAN01041.1 - 0.0008 19.4 0.1 0.079 12.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAN01041.1 - 0.0012 18.2 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN01041.1 - 0.0054 17.3 0.2 0.79 10.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAN01041.1 - 0.019 13.8 0.0 0.039 12.7 0.0 1.5 2 0 0 2 2 2 0 MCRA family HI0933_like PF03486.14 GAN01041.1 - 0.032 12.9 0.3 0.52 8.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 GAN01041.1 - 0.037 13.4 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NUC130_3NT PF08158.12 GAN01041.1 - 0.069 13.5 0.1 2.2 8.7 0.1 2.6 2 0 0 2 2 2 0 NUC130/3NT domain Trp_halogenase PF04820.14 GAN01041.1 - 0.087 11.7 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 GAN01041.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain PRELI PF04707.14 GAN01042.1 - 3e-48 163.6 0.2 3.6e-48 163.4 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Pex16 PF08610.10 GAN01043.1 - 8.6e-105 350.5 4.5 1.4e-104 349.8 4.5 1.3 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Anp1 PF03452.14 GAN01044.1 - 3.1e-84 282.5 0.0 3.7e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 Ribosomal_S11 PF00411.19 GAN01044.1 - 9.1e-46 154.8 1.3 1.4e-45 154.1 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Glycos_transf_2 PF00535.26 GAN01044.1 - 1.7e-05 24.7 0.0 0.00048 20.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 FR47 PF08445.10 GAN01045.1 - 0.00069 19.5 0.0 0.0065 16.4 0.0 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 GAN01045.1 - 0.032 14.5 0.0 0.091 13.0 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN01045.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAP2 PF01569.21 GAN01046.1 - 7.3e-08 32.3 4.5 7.3e-08 32.3 4.5 2.3 2 1 0 2 2 2 1 PAP2 superfamily Fer4_5 PF12801.7 GAN01046.1 - 0.042 13.8 1.3 0.042 13.8 1.3 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain FTHFS PF01268.19 GAN01047.1 - 3.5e-264 877.2 0.0 5.4e-264 876.6 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 GAN01047.1 - 1.2e-66 223.0 2.4 1.2e-66 223.0 2.4 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAN01047.1 - 1.6e-38 131.5 2.0 8.8e-38 129.2 2.1 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 GAN01047.1 - 0.0081 15.1 1.6 0.014 14.3 1.6 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DprA_WH PF17782.1 GAN01047.1 - 0.15 12.2 0.0 0.61 10.2 0.0 2.0 1 0 0 1 1 1 0 DprA winged helix domain zf-RING_2 PF13639.6 GAN01049.1 - 1.5e-10 41.3 7.3 2.2e-10 40.7 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN01049.1 - 1.4e-09 37.5 0.8 1.4e-09 37.5 0.8 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAN01049.1 - 2.8e-07 30.2 8.0 4.5e-07 29.6 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN01049.1 - 4.5e-06 26.9 7.1 2.3e-05 24.6 7.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAN01049.1 - 6.2e-06 26.0 5.8 8.8e-06 25.5 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN01049.1 - 8.8e-06 25.6 1.2 8.8e-06 25.6 1.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAN01049.1 - 1.9e-05 24.5 6.5 3e-05 23.9 6.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAN01049.1 - 4e-05 23.4 7.1 7.1e-05 22.6 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Seryl_tRNA_N PF02403.22 GAN01049.1 - 0.00044 20.4 5.5 0.0006 20.0 5.5 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Prok-RING_4 PF14447.6 GAN01049.1 - 0.00081 19.2 6.8 0.0015 18.3 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HIP1_clath_bdg PF16515.5 GAN01049.1 - 0.001 19.7 2.8 0.0014 19.1 2.8 1.3 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec20 PF03908.13 GAN01049.1 - 0.0062 16.4 2.0 0.0096 15.8 2.0 1.3 1 0 0 1 1 1 1 Sec20 zf-ANAPC11 PF12861.7 GAN01049.1 - 0.019 15.0 3.6 0.033 14.2 3.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger BRE1 PF08647.11 GAN01049.1 - 0.02 15.0 6.9 0.029 14.4 6.9 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fzo_mitofusin PF04799.13 GAN01049.1 - 0.02 14.4 0.9 0.025 14.1 0.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region zf-Nse PF11789.8 GAN01049.1 - 0.04 13.7 3.6 0.04 13.7 3.6 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 GAN01049.1 - 0.05 13.5 4.5 0.09 12.7 4.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PI_PP_I PF18363.1 GAN01049.1 - 0.06 13.5 2.5 0.11 12.7 2.5 1.5 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Pox_A3L PF05288.11 GAN01049.1 - 0.081 12.9 2.1 0.086 12.8 0.1 2.1 2 1 0 2 2 2 0 Poxvirus A3L Protein Rad50_zn_hook PF04423.14 GAN01049.1 - 0.089 12.6 11.1 0.39 10.6 0.1 3.3 3 1 1 4 4 3 0 Rad50 zinc hook motif Baculo_RING PF05883.11 GAN01049.1 - 0.1 12.6 2.9 0.14 12.2 2.9 1.6 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain FapA PF03961.13 GAN01049.1 - 0.14 10.8 4.9 0.16 10.6 4.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Swi5 PF07061.11 GAN01049.1 - 0.14 12.2 5.7 0.24 11.5 5.7 1.4 1 0 0 1 1 1 0 Swi5 UPF0547 PF10571.9 GAN01049.1 - 0.27 11.3 2.6 15 5.8 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.6 GAN01049.1 - 1 9.2 4.9 2.3 8.1 4.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CpXC PF14353.6 GAN01049.1 - 1.3 9.1 6.8 3.7 7.6 6.8 1.8 1 1 0 1 1 1 0 CpXC protein zf-C3HC4_4 PF15227.6 GAN01049.1 - 3.8 7.8 8.5 18 5.6 8.5 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF572 PF04502.13 GAN01050.1 - 4.3e-75 253.4 15.1 2.5e-74 250.9 15.1 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 GAN01050.1 - 0.043 13.9 2.8 1.4 9.1 0.5 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain HypA PF01155.19 GAN01050.1 - 0.11 12.6 0.3 0.57 10.2 0.3 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA E6 PF00518.17 GAN01050.1 - 0.15 12.5 0.3 6.9 7.2 0.0 2.3 1 1 1 2 2 2 0 Early Protein (E6) zinc_ribbon_4 PF13717.6 GAN01050.1 - 0.19 11.7 1.0 5.7 7.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Mut7-C PF01927.16 GAN01050.1 - 0.36 10.9 3.5 29 4.7 0.4 2.8 2 1 1 3 3 3 0 Mut7-C RNAse domain TF_Zn_Ribbon PF08271.12 GAN01050.1 - 0.36 10.4 2.4 3.7 7.1 0.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-NADH-PPase PF09297.11 GAN01050.1 - 0.79 9.4 2.8 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CpXC PF14353.6 GAN01050.1 - 0.88 9.6 4.4 7.7 6.6 0.0 2.9 2 1 1 3 3 3 0 CpXC protein DUF3449 PF11931.8 GAN01050.1 - 0.91 9.3 4.4 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) ThrE PF06738.12 GAN01051.1 - 8.1e-47 159.6 20.7 1.4e-45 155.5 6.1 2.5 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAN01051.1 - 1.7e-07 31.4 31.8 3.5e-05 23.9 7.9 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Zn_clus PF00172.18 GAN01052.1 - 1.4e-08 34.7 12.5 2.7e-08 33.8 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3450 PF11932.8 GAN01052.1 - 4.4 6.5 7.6 0.35 10.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Roughex PF06020.11 GAN01053.1 - 0.011 14.9 3.2 0.014 14.5 3.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 GAN01053.1 - 2.5 6.6 14.3 2.9 6.3 14.3 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 GAN01053.1 - 6.8 5.0 10.8 8.8 4.7 10.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 AIG1 PF04548.16 GAN01054.1 - 4.5e-19 68.6 1.0 1.3e-18 67.2 1.0 1.7 1 1 0 1 1 1 1 AIG1 family Septin PF00735.18 GAN01054.1 - 1.2e-08 34.6 0.0 2.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN01054.1 - 5.8e-08 32.8 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAN01054.1 - 7.1e-05 22.9 5.1 0.0064 16.6 0.1 2.6 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 GAN01054.1 - 0.0013 18.7 2.3 0.0043 17.0 1.0 2.4 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 GAN01054.1 - 0.029 14.6 0.2 0.11 12.7 0.2 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAN01054.1 - 0.083 12.4 0.1 0.53 9.8 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Rad9 PF04139.13 GAN01055.1 - 6.8e-24 84.7 0.5 2.3e-20 73.1 0.3 2.1 1 1 1 2 2 2 2 Rad9 CotJB PF12652.7 GAN01055.1 - 0.0018 18.5 0.1 0.0041 17.3 0.1 1.5 1 0 0 1 1 1 1 CotJB protein RicinB_lectin_2 PF14200.6 GAN01056.1 - 8.5e-13 48.8 0.0 2.5e-06 28.1 0.0 2.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN01056.1 - 5.1e-10 39.7 0.0 6.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PKD_3 PF16820.5 GAN01056.1 - 0.065 13.0 0.1 0.16 11.8 0.0 1.8 2 1 0 2 2 2 0 PKD-like domain Autoind_bind PF03472.15 GAN01056.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Autoinducer binding domain Hexokinase_2 PF03727.16 GAN01057.1 - 7e-66 222.1 0.0 1.2e-65 221.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN01057.1 - 6.6e-46 156.7 0.0 9.3e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Cullin PF00888.22 GAN01058.1 - 1.5e-147 492.9 6.9 2e-147 492.5 6.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAN01058.1 - 3.4e-25 87.9 7.3 1.4e-24 85.9 5.3 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4070 PF13282.6 GAN01058.1 - 0.0034 17.5 0.1 0.012 15.7 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4070) NCD2 PF04905.13 GAN01059.1 - 2.5e-06 27.5 4.1 4.8e-06 26.6 0.0 2.7 2 1 0 2 2 2 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 GAN01059.1 - 0.00072 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) GrpB PF04229.14 GAN01059.1 - 0.0022 18.2 3.5 0.0044 17.2 3.5 1.5 1 0 0 1 1 1 1 GrpB protein SAM_2 PF07647.17 GAN01059.1 - 0.067 13.3 0.1 0.25 11.5 0.1 2.0 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4200 PF13863.6 GAN01059.1 - 0.44 11.0 18.7 0.054 13.9 7.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.16 GAN01059.1 - 9.8 5.0 6.9 10 4.9 6.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DNA_pol_A PF00476.20 GAN01060.1 - 0.00086 18.5 2.1 0.0014 17.8 2.1 1.2 1 0 0 1 1 1 1 DNA polymerase family A WSK PF03832.13 GAN01060.1 - 0.0033 17.1 1.3 0.0033 17.1 1.3 2.9 4 0 0 4 4 4 1 WSK motif NAD_binding_2 PF03446.15 GAN01061.1 - 4.4e-33 114.7 0.1 6.4e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAN01061.1 - 1e-08 35.4 0.0 1.7e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAN01061.1 - 2.2e-07 31.3 0.0 5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAN01061.1 - 1.7e-06 28.1 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAN01061.1 - 0.076 12.6 1.5 0.082 12.5 0.2 1.8 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDH PF02153.17 GAN01061.1 - 0.088 11.8 0.6 0.17 10.8 0.4 1.5 1 1 0 1 1 1 0 Prephenate dehydrogenase zf-MIZ PF02891.20 GAN01062.1 - 1.1e-10 41.1 0.9 2.3e-10 40.0 0.9 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.15 GAN01062.1 - 0.019 15.0 2.8 0.71 10.0 0.4 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-Nse PF11789.8 GAN01062.1 - 0.07 13.0 0.5 0.16 11.8 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RAP1 PF07218.11 GAN01064.1 - 3.8 5.7 12.6 6 5.0 12.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FSA_C PF10479.9 GAN01064.1 - 8.7 4.3 20.8 19 3.2 20.8 1.5 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pol_alpha_B_N PF08418.10 GAN01064.1 - 9 6.2 15.7 9.8 6.1 11.4 2.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal HLH PF00010.26 GAN01066.1 - 8e-16 57.8 1.0 1.8e-15 56.6 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MS_channel PF00924.18 GAN01067.1 - 4.4e-15 55.8 2.4 7.9e-15 55.0 2.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 GAN01067.1 - 0.00082 18.7 0.1 0.0018 17.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAN01067.1 - 0.00086 19.0 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAN01067.1 - 0.0034 16.8 0.1 0.0088 15.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAN01067.1 - 0.02 15.3 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Methyltransf_25 PF13649.6 GAN01068.1 - 1.4e-14 54.5 0.0 3.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN01068.1 - 2e-13 50.8 0.0 4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN01068.1 - 1.2e-11 44.7 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN01068.1 - 4.4e-11 42.8 0.0 8.4e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN01068.1 - 7.6e-05 22.2 0.0 0.00015 21.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 GAN01068.1 - 9.1e-05 21.2 0.0 0.00013 20.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 GAN01068.1 - 0.00014 22.5 0.0 0.00036 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 GAN01068.1 - 0.00017 21.3 0.1 0.00033 20.4 0.1 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_8 PF05148.15 GAN01068.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 GAN01068.1 - 0.00073 18.9 0.0 0.0014 17.9 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 GAN01068.1 - 0.0041 17.2 0.0 0.0094 16.1 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 GAN01068.1 - 0.0057 16.1 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.14 GAN01068.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Cyclin_N PF00134.23 GAN01069.1 - 2.3e-10 40.3 0.4 4.2e-10 39.5 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN01069.1 - 7.9e-07 29.6 0.1 1.5e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin zf-CCCH PF00642.24 GAN01070.1 - 1.1e-20 73.0 35.5 2.8e-05 23.9 1.6 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAN01070.1 - 1.2e-16 60.1 59.3 8.5e-08 32.0 6.0 5.8 6 0 0 6 6 6 5 Zinc finger domain Torus PF16131.5 GAN01070.1 - 5.3e-14 52.8 40.3 7e-05 23.5 0.7 6.2 1 1 5 6 6 6 5 Torus domain zf-CCCH_4 PF18044.1 GAN01070.1 - 1.2e-10 40.9 44.0 1.2e-05 24.9 3.0 5.5 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 GAN01070.1 - 2.3e-07 31.0 5.9 2.3e-07 31.0 5.9 3.3 1 1 2 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 GAN01070.1 - 1.3e-06 28.7 44.7 0.0095 16.4 2.1 6.0 6 0 0 6 6 6 4 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 GAN01070.1 - 2.1e-06 27.6 3.6 2.1e-06 27.6 3.6 2.7 2 0 0 2 2 2 1 Zinc knuckle Cyclin PF08613.11 GAN01070.1 - 0.1 13.0 2.4 0.15 12.4 2.4 1.2 1 0 0 1 1 1 0 Cyclin DUF4171 PF13775.6 GAN01070.1 - 0.21 12.1 4.5 0.34 11.3 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) NAD_binding_8 PF13450.6 GAN01071.1 - 2.4e-15 56.5 0.0 4.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAN01071.1 - 1.3e-05 25.2 0.0 0.025 14.6 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAN01071.1 - 3.7e-05 23.1 0.0 0.039 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN01071.1 - 3.9e-05 23.4 0.0 8.3e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAN01071.1 - 0.00019 20.9 0.0 0.0026 17.1 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase MCRA PF06100.11 GAN01071.1 - 0.0058 15.5 0.0 0.013 14.3 0.0 1.6 2 0 0 2 2 2 1 MCRA family FAD_binding_2 PF00890.24 GAN01071.1 - 0.016 14.3 0.1 0.03 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GAN01071.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 GAN01071.1 - 0.022 13.5 0.1 0.83 8.3 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein Per1 PF04080.13 GAN01072.1 - 8.3e-101 337.0 11.4 1e-100 336.8 11.4 1.1 1 0 0 1 1 1 1 Per1-like family COLFI PF01410.18 GAN01072.1 - 0.09 12.1 0.3 0.13 11.5 0.3 1.1 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain ThrE PF06738.12 GAN01072.1 - 0.14 11.5 1.2 0.25 10.7 1.2 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter Forkhead PF00250.18 GAN01073.1 - 4.2e-35 119.9 0.5 9e-35 118.8 0.5 1.6 1 0 0 1 1 1 1 Forkhead domain Band_7 PF01145.25 GAN01074.1 - 2.5e-24 86.3 3.4 4.1e-24 85.6 3.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 GAN01074.1 - 0.093 12.9 0.3 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Translin PF01997.16 GAN01075.1 - 1.6e-44 152.4 0.1 1.9e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 Translin family BST2 PF16716.5 GAN01075.1 - 0.003 18.1 0.1 0.0092 16.5 0.1 1.8 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 Intein_splicing PF14890.6 GAN01075.1 - 0.0062 16.5 0.1 0.014 15.3 0.1 1.5 1 1 0 1 1 1 1 Intein splicing domain Syntaxin-6_N PF09177.11 GAN01075.1 - 0.012 16.1 2.4 6.8 7.3 0.1 3.3 2 1 0 3 3 3 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 GAN01075.1 - 0.025 14.6 2.1 1 9.4 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PI_PP_I PF18363.1 GAN01075.1 - 0.045 13.9 0.3 3.5 7.9 0.1 2.8 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF1664 PF07889.12 GAN01075.1 - 0.075 13.1 1.1 9.3 6.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) GMP_synt_C PF00958.22 GAN01075.1 - 0.084 12.9 0.2 0.23 11.5 0.1 1.8 1 1 0 1 1 1 0 GMP synthase C terminal domain DUF1479 PF07350.12 GAN01075.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Nas2_N PF18265.1 GAN01075.1 - 0.46 10.4 3.1 1.7 8.7 0.1 2.9 3 0 0 3 3 3 0 Nas2 N_terminal domain MHYT PF03707.16 GAN01076.1 - 7.5e-22 77.3 20.5 4.2e-09 36.4 1.2 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat EXS PF03124.14 GAN01076.1 - 1.1 8.5 8.3 1.4 8.2 7.2 1.6 1 1 0 1 1 1 0 EXS family Virul_fac_BrkB PF03631.15 GAN01076.1 - 1.7 8.2 17.6 3.5 7.2 17.6 1.4 1 0 0 1 1 1 0 Virulence factor BrkB Nucleopor_Nup85 PF07575.13 GAN01077.1 - 1.8e-40 139.1 16.0 1.3e-39 136.3 16.0 1.8 1 1 0 1 1 1 1 Nup85 Nucleoporin TPR_1 PF00515.28 GAN01077.1 - 0.13 12.2 3.8 0.076 12.9 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN01077.1 - 0.13 12.4 2.0 0.48 10.7 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 GAN01078.1 - 0.21 12.5 2.5 8.1 7.6 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 GAN01078.1 - 0.6 10.8 3.4 6.3 7.5 0.1 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zip PF02535.22 GAN01078.1 - 1.5 7.9 2.9 1.8 7.7 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RRM_1 PF00076.22 GAN01079.1 - 2.6e-16 59.2 0.0 4.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN01079.1 - 0.025 14.7 0.1 0.099 12.8 0.1 2.1 1 1 0 1 1 1 0 RNA recognition motif ANAPC1 PF12859.7 GAN01079.1 - 5 7.7 9.7 10 6.7 9.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 eIF-1a PF01176.19 GAN01080.1 - 3.2e-21 74.9 0.1 4.4e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 EBP PF05241.12 GAN01081.1 - 8.4e-22 77.5 0.4 1e-21 77.2 0.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF3611 PF12263.8 GAN01081.1 - 0.031 14.2 1.0 0.07 13.0 1.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) DUF2781 PF10914.8 GAN01083.1 - 7.2e-42 143.3 13.3 9.9e-42 142.8 13.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) O-antigen_lig PF13425.6 GAN01083.1 - 0.077 11.8 1.2 0.094 11.5 1.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Prefoldin PF02996.17 GAN01084.1 - 1.4e-20 73.4 0.7 1.7e-20 73.1 0.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1685 PF07939.11 GAN01084.1 - 0.074 12.8 0.1 2.5 7.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1685) Prefoldin_2 PF01920.20 GAN01084.1 - 0.22 11.5 5.9 0.31 11.0 0.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit TatD_DNase PF01026.21 GAN01085.1 - 3.5e-54 183.9 0.0 4.4e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Oxidored_q6 PF01058.22 GAN01085.1 - 0.07 13.0 0.1 1.9 8.3 0.1 2.8 2 1 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit AAA PF00004.29 GAN01086.1 - 6.9e-42 143.0 0.0 1.2e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAN01086.1 - 2.7e-10 40.0 0.2 5.4e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAN01086.1 - 3.3e-09 36.4 0.4 6.3e-09 35.5 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAN01086.1 - 4.8e-06 26.8 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAN01086.1 - 2.7e-05 23.5 0.0 4.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAN01086.1 - 4.7e-05 23.7 0.2 0.029 14.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAN01086.1 - 0.0001 22.4 0.3 0.0012 18.9 0.2 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN01086.1 - 0.00022 21.7 0.1 0.0067 16.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAN01086.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAN01086.1 - 0.0023 18.5 0.1 0.006 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 GAN01086.1 - 0.0059 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAN01086.1 - 0.0073 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAN01086.1 - 0.009 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAN01086.1 - 0.011 15.1 0.6 0.27 10.5 0.1 2.7 2 1 1 3 3 3 0 KaiC Prot_ATP_OB_N PF17758.1 GAN01086.1 - 0.021 14.5 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 GAN01086.1 - 0.025 14.8 0.5 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAN01086.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 GAN01086.1 - 0.047 12.9 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 GAN01086.1 - 0.064 12.4 0.0 0.61 9.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF1128 PF06569.11 GAN01086.1 - 0.095 12.7 0.1 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) AAA_24 PF13479.6 GAN01086.1 - 0.1 12.3 0.3 0.33 10.7 0.3 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAN01086.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 GAN01086.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 GAN01086.1 - 0.11 12.4 0.1 0.78 9.6 0.1 2.2 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 GAN01086.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 GAN01086.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 GAN01086.1 - 0.23 11.2 0.4 0.64 9.7 0.4 1.7 1 1 0 1 1 1 0 AAA domain YL1_C PF08265.11 GAN01087.1 - 3.3e-17 61.9 0.4 6.7e-17 60.9 0.4 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ank_2 PF12796.7 GAN01088.1 - 2.7e-14 53.5 0.1 3.6e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAN01088.1 - 1.4e-12 47.5 0.9 1.4e-05 25.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAN01088.1 - 3.5e-12 46.6 0.1 5.9e-05 23.5 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN01088.1 - 1.7e-11 43.2 2.1 0.001 19.3 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAN01088.1 - 4.9e-11 42.6 0.7 1.6e-07 31.4 0.6 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HECT PF00632.25 GAN01088.1 - 0.19 11.2 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DUF1356 PF07092.12 GAN01089.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) BppU_IgG PF18667.1 GAN01089.1 - 0.032 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain FAD_syn PF06574.12 GAN01089.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD synthetase Vac7 PF12751.7 GAN01089.1 - 0.076 12.4 2.1 1.4 8.3 3.7 1.9 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Orf78 PF06024.12 GAN01089.1 - 0.16 12.3 1.2 0.56 10.5 0.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Arrestin_C PF02752.22 GAN01090.1 - 2.8e-19 69.9 0.3 2.6e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN01090.1 - 2.7e-14 53.5 0.0 5.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN01090.1 - 0.00089 19.0 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like CoA_transf_3 PF02515.17 GAN01091.1 - 1.5e-36 126.3 0.0 6e-35 121.0 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III AIG1 PF04548.16 GAN01092.1 - 1.6e-15 57.0 0.0 2.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GAN01092.1 - 2.6e-07 30.7 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN01092.1 - 4e-05 23.6 0.0 0.00012 22.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 GAN01092.1 - 0.00024 20.5 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 GAN01092.1 - 0.0011 19.0 0.1 0.27 11.3 0.1 2.4 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.27 GAN01092.1 - 0.015 15.9 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Transposase_28 PF04195.12 GAN01092.1 - 0.031 14.5 0.2 0.057 13.6 0.2 1.4 1 0 0 1 1 1 0 Putative gypsy type transposon IIGP PF05049.13 GAN01092.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 GAN01092.1 - 0.097 12.9 0.3 0.41 10.9 0.2 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Hamartin PF04388.12 GAN01093.1 - 1.2 7.7 30.2 0.2 10.3 26.4 1.5 2 0 0 2 2 2 0 Hamartin protein Catalase PF00199.19 GAN01095.1 - 1.7e-166 554.1 0.1 2.3e-166 553.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 GAN01095.1 - 1.2e-33 115.9 0.0 2.3e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 GAN01095.1 - 3.5e-20 72.0 0.3 7.7e-20 70.9 0.3 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive PALP PF00291.25 GAN01097.1 - 2.7e-68 230.5 1.6 3.3e-68 230.3 1.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Toprim_3 PF13362.6 GAN01097.1 - 0.0057 17.0 0.0 0.076 13.4 0.0 2.6 3 0 0 3 3 3 1 Toprim domain Phage_holin_3_2 PF04550.12 GAN01097.1 - 0.11 13.0 0.7 9.2 6.9 0.1 2.7 2 1 0 2 2 2 0 Phage holin family 2 Ribosomal_L16 PF00252.18 GAN01098.1 - 1.3e-46 157.9 0.7 1.7e-46 157.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Zn_clus PF00172.18 GAN01099.1 - 9.6e-05 22.4 14.7 0.00016 21.7 14.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coatomer_E PF04733.14 GAN01099.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Coatomer epsilon subunit FSH1 PF03959.13 GAN01100.1 - 1.7e-51 174.9 0.0 2.4e-50 171.2 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 GAN01100.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Vwaint PF14624.6 GAN01100.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 VWA / Hh protein intein-like ADH_N PF08240.12 GAN01101.1 - 1.3e-24 86.1 4.6 2.3e-24 85.4 4.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN01101.1 - 1.3e-15 57.6 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN01101.1 - 4.3e-05 24.6 0.0 7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAN01101.1 - 0.0007 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAN01101.1 - 0.0013 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF4537 PF15057.6 GAN01101.1 - 0.1 12.7 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) 6PF2K PF01591.18 GAN01102.1 - 8.2e-80 267.3 1.0 1e-79 266.9 1.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAN01102.1 - 5.7e-33 114.2 0.0 8.5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAN01102.1 - 0.00073 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain HLH PF00010.26 GAN01103.1 - 1.4e-12 47.4 1.1 1.4e-12 47.4 1.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4468 PF14730.6 GAN01103.1 - 0.13 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold KIAA1430 PF13879.6 GAN01103.1 - 8.3 7.2 13.4 0.63 10.8 2.2 3.1 1 1 3 4 4 4 0 KIAA1430 homologue adh_short PF00106.25 GAN01105.1 - 2e-28 99.2 0.0 3.8e-23 82.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAN01105.1 - 4.7e-14 52.5 0.0 1.7e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN01105.1 - 2.4e-05 24.3 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 KR domain FeS_assembly_P PF01883.19 GAN01106.1 - 9.1e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein FolB PF02152.18 GAN01106.1 - 0.015 15.9 0.5 0.15 12.6 0.1 2.1 1 1 1 2 2 2 0 Dihydroneopterin aldolase Pkinase PF00069.25 GAN01107.1 - 4.8e-60 203.2 0.0 7.1e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01107.1 - 3.7e-41 141.1 0.0 6.7e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAN01107.1 - 8e-08 32.5 0.1 6.1e-07 29.7 0.0 2.6 3 0 0 3 3 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAN01107.1 - 0.00013 20.8 1.4 0.00014 20.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase zf-RING_2 PF13639.6 GAN01107.1 - 0.00021 21.6 2.5 0.00048 20.4 2.5 1.6 1 0 0 1 1 1 1 Ring finger domain Kinase-like PF14531.6 GAN01107.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-RING_5 PF14634.6 GAN01107.1 - 0.0029 17.5 2.5 0.0058 16.6 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAN01107.1 - 0.0057 16.7 2.0 0.013 15.5 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAN01107.1 - 0.0071 16.6 3.1 0.015 15.5 3.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAN01107.1 - 0.015 15.2 3.6 0.032 14.1 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN01107.1 - 0.016 14.9 10.4 0.61 9.9 10.4 2.7 1 1 0 1 1 1 0 RING-like zinc finger Kdo PF06293.14 GAN01107.1 - 0.018 14.4 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_2 PF13923.6 GAN01107.1 - 0.031 14.1 0.3 0.031 14.1 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) APH PF01636.23 GAN01107.1 - 0.048 13.6 0.1 2 8.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family BAR_2 PF10455.9 GAN01108.1 - 1.4e-49 168.8 2.4 1.5e-27 96.5 0.0 2.2 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 GAN01108.1 - 2.4e-25 89.6 1.5 5.9e-25 88.3 1.5 1.6 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAN01108.1 - 5.4e-07 29.6 0.3 6.2e-06 26.1 0.2 2.3 1 1 0 1 1 1 1 BAR domain of APPL family CAP-ZIP_m PF15255.6 GAN01108.1 - 0.095 13.0 8.0 0.41 10.9 0.1 3.3 2 1 1 3 3 3 0 WASH complex subunit CAP-Z interacting, central region RT_RNaseH_2 PF17919.1 GAN01111.1 - 5.2e-36 122.7 0.0 1.4e-35 121.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAN01111.1 - 7.1e-35 119.5 0.0 2.1e-34 118.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAN01111.1 - 1.6e-22 80.1 0.2 4.1e-22 78.8 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAN01111.1 - 3.3e-15 55.9 1.9 4.3e-15 55.6 0.4 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GAN01111.1 - 4.4e-15 55.9 0.0 8.6e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 GAN01111.1 - 3.6e-05 23.8 0.9 7.8e-05 22.7 0.3 1.9 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain zf-CCHC PF00098.23 GAN01111.1 - 0.00095 19.1 4.7 0.0022 18.0 4.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 GAN01111.1 - 0.089 12.6 0.7 0.29 11.0 0.7 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GAN01111.1 - 0.095 12.6 3.4 0.26 11.2 3.4 1.7 1 0 0 1 1 1 0 Zinc knuckle NGP1NT PF08153.12 GAN01112.1 - 4e-54 182.3 0.6 4e-54 182.3 0.6 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 GAN01112.1 - 6.6e-17 61.6 0.5 1.1e-12 48.0 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase Arf PF00025.21 GAN01112.1 - 3.6e-05 23.3 0.1 0.053 13.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 GAN01112.1 - 0.00011 21.7 0.0 0.0017 17.9 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAN01112.1 - 0.0022 17.9 0.0 0.006 16.5 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 GAN01112.1 - 0.0088 15.6 0.0 0.55 9.8 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAN01112.1 - 0.029 14.4 7.2 2.5 8.1 0.0 4.1 3 1 1 4 4 4 0 Dynamin family Glyco_transf_5 PF08323.11 GAN01112.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain L51_S25_CI-B8 PF05047.16 GAN01113.1 - 1.4e-11 44.1 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Lipase_GDSL_3 PF14606.6 GAN01113.1 - 0.073 13.2 0.0 0.088 12.9 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family tRNA-synt_1g PF09334.11 GAN01114.1 - 6.6e-151 502.5 0.1 8.9e-151 502.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAN01114.1 - 6.4e-09 34.6 0.1 2.1e-05 23.0 0.0 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) GST_C_3 PF14497.6 GAN01114.1 - 0.00016 21.8 0.1 0.00057 20.0 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Anticodon_1 PF08264.13 GAN01114.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA MetRS-N PF09635.10 GAN01114.1 - 0.021 15.3 0.5 0.052 14.1 0.5 1.6 1 0 0 1 1 1 0 MetRS-N binding domain zinc-ribbons_6 PF07191.12 GAN01114.1 - 0.024 14.6 2.3 0.062 13.3 2.3 1.6 1 0 0 1 1 1 0 zinc-ribbons HypA PF01155.19 GAN01114.1 - 0.18 11.8 2.2 0.51 10.4 1.6 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 GAN01114.1 - 2.3 8.2 4.7 0.3 11.0 0.4 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.6 GAN01115.1 - 2e-23 81.7 27.7 1.9e-07 31.2 0.5 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 GAN01115.1 - 1.1e-20 72.8 30.6 2.8e-05 24.3 1.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN01115.1 - 1.7e-10 40.8 28.1 0.0026 18.4 1.4 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN01115.1 - 0.0016 18.7 4.6 4 7.8 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 GAN01115.1 - 0.11 13.2 0.7 0.11 13.2 0.7 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 GAN01115.1 - 0.17 11.7 16.4 1.3 8.8 1.0 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type Ogr_Delta PF04606.12 GAN01115.1 - 0.23 11.5 10.2 0.13 12.2 0.6 3.8 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger zf-met PF12874.7 GAN01115.1 - 0.26 11.7 10.0 26 5.4 0.1 5.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAN01115.1 - 1.1 9.4 17.2 3 7.9 0.8 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 GAN01115.1 - 2.4 8.9 15.5 7.3 7.3 0.3 4.4 3 1 2 5 5 5 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 GAN01115.1 - 2.7 8.1 8.3 11 6.2 0.4 3.1 1 1 2 3 3 3 0 Aberrant zinc-finger GPI-anchored PF10342.9 GAN01117.1 - 1.6e-09 38.4 0.9 2.4e-09 37.8 0.9 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FA_desaturase PF00487.24 GAN01118.1 - 2e-17 63.9 19.6 3.1e-17 63.2 19.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAN01118.1 - 4.1e-12 46.1 0.0 9.8e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MerC PF03203.14 GAN01118.1 - 0.067 13.7 0.3 0.067 13.7 0.3 2.1 2 0 0 2 2 2 0 MerC mercury resistance protein Ish1 PF10281.9 GAN01119.1 - 0.023 15.0 1.6 0.34 11.2 1.5 2.8 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein RVT_1 PF00078.27 GAN01119.1 - 0.072 12.6 3.7 0.084 12.4 0.1 2.8 3 1 1 4 4 4 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cys_rich_CPCC PF14206.6 GAN01119.1 - 0.12 12.2 0.4 0.37 10.6 0.1 2.0 2 0 0 2 2 2 0 Cysteine-rich CPCC PASTA PF03793.19 GAN01119.1 - 0.26 11.2 0.1 0.26 11.2 0.1 3.1 5 0 0 5 5 5 0 PASTA domain WcbI PF18588.1 GAN01119.1 - 1.3 8.6 4.3 2.9 7.4 0.6 2.8 4 0 0 4 4 4 0 Polysaccharide biosynthesis enzyme WcbI DUF3181 PF11378.8 GAN01119.1 - 1.8 8.9 5.6 3.5 8.0 0.1 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF3181) Bac_DNA_binding PF00216.21 GAN01119.1 - 9 6.6 7.2 16 5.8 0.2 3.4 4 0 0 4 4 4 0 Bacterial DNA-binding protein Glyco_hydro_3_C PF01915.22 GAN01120.1 - 7.7e-61 205.6 0.1 1.8e-60 204.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAN01120.1 - 8e-39 133.9 0.0 1.5e-38 133.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAN01120.1 - 1.9e-23 82.3 0.0 4.3e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 GAN01121.1 - 9.4e-55 185.7 0.1 2.1e-54 184.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAN01121.1 - 1.6e-40 139.5 0.0 3.1e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAN01121.1 - 9.4e-21 73.7 0.0 2.2e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Metallopep PF12044.8 GAN01123.1 - 2.2e-130 435.1 0.0 2.8e-130 434.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 GAN01123.1 - 0.00019 21.4 0.3 0.00068 19.6 0.0 2.0 2 0 0 2 2 2 1 Jacalin-like lectin domain HSP70 PF00012.20 GAN01124.1 - 5.8e-104 348.4 5.8 5.8e-104 348.4 5.8 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GAN01124.1 - 5.3e-15 55.0 1.7 8.8e-15 54.3 1.2 1.6 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 GAN01124.1 - 1.8e-05 23.9 0.5 0.027 13.5 0.2 2.4 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; TFIIS_C PF01096.18 GAN01125.1 - 1.9e-18 66.0 4.6 1.9e-18 66.0 4.6 2.7 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAN01125.1 - 8e-08 32.0 4.0 1.6e-07 31.1 0.9 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 GAN01125.1 - 1.6e-05 24.8 8.3 0.0087 16.0 3.1 2.6 2 1 0 2 2 2 2 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.10 GAN01125.1 - 0.002 17.9 0.5 0.002 17.9 0.5 1.5 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger zf-ribbon_3 PF13248.6 GAN01125.1 - 0.0038 16.6 4.7 0.46 10.0 0.1 3.1 3 0 0 3 3 3 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 GAN01125.1 - 0.0068 15.9 1.2 2.2 7.8 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DpnI PF06044.12 GAN01125.1 - 0.043 13.5 0.4 0.043 13.5 0.4 2.1 1 1 1 2 2 2 0 Dam-replacing family Cys_rich_KTR PF14205.6 GAN01125.1 - 0.048 13.5 4.2 4.1 7.3 0.1 3.1 2 1 1 3 3 3 0 Cysteine-rich KTR PcF PF09461.10 GAN01125.1 - 0.05 14.0 5.1 3.6 8.0 1.5 2.4 2 0 0 2 2 2 0 Phytotoxin PcF protein zf-RRPl_C4 PF17026.5 GAN01125.1 - 0.055 13.6 3.3 0.082 13.0 3.3 1.4 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Baculo_LEF5_C PF11792.8 GAN01125.1 - 0.089 12.5 2.1 0.21 11.3 2.1 1.7 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_2 PF13240.6 GAN01125.1 - 0.097 12.4 7.0 5.5 6.9 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 GAN01125.1 - 0.16 12.2 4.0 0.88 9.8 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HscB_4_cys PF18256.1 GAN01125.1 - 0.18 11.7 8.5 2.7 7.9 0.6 3.3 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zinc_ribbon_4 PF13717.6 GAN01125.1 - 1 9.3 15.2 2.1 8.3 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-C3HC4_4 PF15227.6 GAN01125.1 - 6.4 7.0 12.5 7.8 6.7 3.0 3.1 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Ribosomal_S27e PF01667.17 GAN01125.1 - 7.2 6.4 8.7 3.1 7.6 0.1 2.6 3 0 0 3 3 3 0 Ribosomal protein S27 Kelch_4 PF13418.6 GAN01126.1 - 3.7e-26 90.9 6.1 6.6e-06 26.0 0.1 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN01126.1 - 1.3e-25 88.9 1.6 8.8e-06 25.6 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 GAN01126.1 - 5e-25 86.9 4.9 4.4e-08 33.1 0.2 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAN01126.1 - 2.8e-23 81.2 0.6 8.4e-06 25.3 0.0 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 GAN01126.1 - 5.5e-23 80.7 0.2 2.3e-05 24.6 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN01126.1 - 6.3e-12 45.0 2.4 0.0015 18.5 0.1 6.1 6 0 0 6 6 6 2 Kelch motif Sas10_Utp3 PF04000.15 GAN01127.1 - 5.5e-18 65.4 2.0 1.9e-17 63.6 2.0 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CRAL_TRIO PF00650.20 GAN01128.1 - 3.9e-12 46.2 0.0 9.8e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain WWE PF02825.20 GAN01129.1 - 0.00042 20.8 1.0 0.00055 20.5 1.0 1.4 1 1 0 1 1 1 1 WWE domain GATA PF00320.27 GAN01130.1 - 2.5e-10 39.8 13.4 2.1e-06 27.2 1.3 2.7 3 0 0 3 3 3 2 GATA zinc finger zf-3CxxC PF13695.6 GAN01130.1 - 0.027 14.9 2.8 0.033 14.7 1.8 1.7 1 1 0 1 1 1 0 Zinc-binding domain SR-25 PF10500.9 GAN01130.1 - 5.9 6.4 14.5 2.5 7.7 7.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_14 PF13428.6 GAN01131.1 - 3.4e-15 55.4 23.2 0.018 15.8 0.1 11.6 6 4 6 12 12 12 4 Tetratricopeptide repeat Suf PF05843.14 GAN01131.1 - 8.3e-15 55.5 14.2 0.02 14.9 0.2 6.9 4 1 3 8 8 8 5 Suppressor of forked protein (Suf) TPR_8 PF13181.6 GAN01131.1 - 6.5e-08 32.2 10.4 0.011 15.8 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat NRDE-2 PF08424.10 GAN01131.1 - 2.1e-07 30.4 7.3 0.0014 17.9 0.4 5.8 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 GAN01131.1 - 2e-06 27.5 21.0 2.8 8.3 0.0 9.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN01131.1 - 1.7e-05 25.2 6.9 1.8 9.1 0.1 5.8 6 1 1 7 7 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAN01131.1 - 2.9e-05 24.0 12.6 1.4 8.9 0.1 6.7 7 2 1 8 8 8 3 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 GAN01131.1 - 5.3e-05 23.4 10.4 0.042 14.1 0.0 6.4 5 2 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.5 GAN01131.1 - 0.013 15.6 0.1 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein ArdA PF07275.11 GAN01131.1 - 0.055 14.1 0.8 0.85 10.2 0.4 2.9 2 0 0 2 2 2 0 Antirestriction protein (ArdA) TPR_16 PF13432.6 GAN01131.1 - 0.058 14.1 13.8 0.23 12.1 0.0 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat CKAP2_C PF15297.6 GAN01131.1 - 0.14 11.3 0.2 1.8 7.6 0.0 2.4 2 1 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus SNAP PF14938.6 GAN01131.1 - 0.49 9.8 9.2 0.26 10.7 0.5 4.0 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 GAN01131.1 - 2.7 8.8 24.9 39 5.2 0.2 8.3 9 1 1 10 10 10 0 Tetratricopeptide repeat DALR_1 PF05746.15 GAN01131.1 - 2.9 8.1 6.0 3.9 7.7 0.0 3.6 4 1 0 4 4 4 0 DALR anticodon binding domain SHMT PF00464.19 GAN01133.1 - 4.3e-205 680.9 0.0 5e-205 680.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 GAN01133.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L27A PF00828.19 GAN01134.1 - 6.4e-41 140.0 0.1 1.4e-40 138.9 0.1 1.5 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NNMT_PNMT_TEMT PF01234.17 GAN01134.1 - 0.049 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF21 PF01595.20 GAN01135.1 - 1e-33 116.5 0.9 3e-33 115.0 0.7 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAN01135.1 - 1.3e-06 28.8 0.7 0.077 13.5 0.2 2.7 2 0 0 2 2 2 2 CBS domain UPF0270 PF06794.12 GAN01135.1 - 0.092 12.8 0.6 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) BTB PF00651.31 GAN01136.1 - 6e-06 26.5 0.0 3.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain RNA_helicase PF00910.22 GAN01136.1 - 0.0046 17.3 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 GAN01136.1 - 0.048 14.2 0.0 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 GAN01136.1 - 0.05 12.6 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 GAN01136.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 GAN01136.1 - 0.078 12.9 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 GAN01136.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Nramp PF01566.18 GAN01137.1 - 8.7e-108 360.5 16.8 8.7e-108 360.5 16.8 2.0 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein DUF4131 PF13567.6 GAN01137.1 - 1.4 8.6 6.2 3.6 7.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) RhoGEF PF00621.20 GAN01138.1 - 1.8e-24 87.0 0.7 5.4e-24 85.4 0.7 1.9 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 GAN01138.1 - 7.2e-17 61.9 0.7 2.5e-16 60.1 0.7 1.9 1 1 0 1 1 1 1 CNH domain SUIM_assoc PF16619.5 GAN01138.1 - 1.3 9.2 13.1 8.2 6.6 7.9 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 GAN01139.1 - 4.6e-14 52.0 0.2 8.7e-07 28.7 0.0 2.2 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GAN01139.1 - 2.3e-06 27.4 5.7 4.2e-06 26.6 5.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GAN01139.1 - 0.00087 19.0 3.0 0.0021 17.7 3.0 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RRM_7 PF16367.5 GAN01139.1 - 0.044 13.9 0.0 0.32 11.1 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif zf-CCHC_2 PF13696.6 GAN01139.1 - 0.11 12.3 4.3 0.18 11.7 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle NTF2 PF02136.20 GAN01140.1 - 0.12 12.9 0.0 0.15 12.6 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DNA_pol_phi PF04931.13 GAN01141.1 - 6.9e-216 718.9 30.3 6.9e-216 718.9 30.3 1.7 2 0 0 2 2 2 1 DNA polymerase phi FliS PF02561.14 GAN01141.1 - 0.13 12.6 2.1 1 9.6 0.2 3.0 1 1 1 2 2 2 0 Flagellar protein FliS YL1 PF05764.13 GAN01141.1 - 0.37 10.9 13.8 0.26 11.4 6.2 2.6 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 GAN01141.1 - 0.66 9.3 16.7 1.7 7.9 16.7 1.7 1 0 0 1 1 1 0 BUD22 DUF4203 PF13886.6 GAN01143.1 - 3.1e-34 118.4 41.1 3.1e-34 118.4 41.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) ABC_tran PF00005.27 GAN01144.1 - 8.2e-35 120.3 0.0 6e-17 62.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 GAN01144.1 - 7.5e-15 54.5 5.6 2.1e-14 53.0 5.6 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 GAN01144.1 - 3.5e-11 43.0 4.4 0.00081 18.9 0.3 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAN01144.1 - 1.5e-10 41.4 11.5 0.0058 16.5 0.1 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 GAN01144.1 - 6.7e-09 35.2 2.9 6.7e-09 35.2 2.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 GAN01144.1 - 1.6e-06 28.0 12.6 3.1e-06 27.0 2.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 GAN01144.1 - 7.9e-06 25.5 0.2 0.053 13.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAN01144.1 - 2.7e-05 24.1 0.1 0.082 12.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 GAN01144.1 - 4.6e-05 23.3 7.0 0.045 13.5 0.1 3.4 2 2 0 3 3 3 2 AAA ATPase domain Fer4_2 PF12797.7 GAN01144.1 - 0.00034 20.5 0.7 0.00034 20.5 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 GAN01144.1 - 0.00052 20.0 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_21 PF14697.6 GAN01144.1 - 0.00081 19.5 11.4 0.0015 18.6 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA PF00004.29 GAN01144.1 - 0.00094 19.6 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_9 PF13187.6 GAN01144.1 - 0.0011 19.1 12.1 0.002 18.3 12.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_16 PF13191.6 GAN01144.1 - 0.0014 19.0 0.0 0.45 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_7 PF12838.7 GAN01144.1 - 0.0016 18.9 10.8 0.0034 17.9 10.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAN01144.1 - 0.0018 18.3 1.0 0.0018 18.3 1.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.22 GAN01144.1 - 0.0029 18.0 0.1 3.4 8.1 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_23 PF13476.6 GAN01144.1 - 0.0035 17.9 3.2 0.075 13.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 GAN01144.1 - 0.0043 17.3 0.0 0.52 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GAN01144.1 - 0.0052 16.5 0.2 4.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase AAA_18 PF13238.6 GAN01144.1 - 0.0075 16.8 0.0 2.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAN01144.1 - 0.0087 15.8 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.6 GAN01144.1 - 0.0094 16.9 7.8 0.015 16.2 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain NACHT PF05729.12 GAN01144.1 - 0.013 15.4 1.6 0.73 9.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 GAN01144.1 - 0.013 15.5 0.8 0.59 10.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAN01144.1 - 0.019 14.2 0.0 0.51 9.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 GAN01144.1 - 0.026 14.2 0.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAN01144.1 - 0.028 14.0 2.3 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 GAN01144.1 - 0.033 14.3 0.9 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 GAN01144.1 - 0.072 12.8 0.0 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_28 PF13521.6 GAN01144.1 - 0.075 13.3 0.7 7.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAN01144.1 - 0.08 11.9 0.2 2.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 GAN01144.1 - 0.083 12.2 0.3 2.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Fer4_8 PF13183.6 GAN01144.1 - 0.097 13.1 0.2 0.097 13.1 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF815 PF05673.13 GAN01144.1 - 0.099 11.8 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 GAN01144.1 - 0.1 12.7 2.6 3.9 7.6 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 GAN01144.1 - 0.14 11.7 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 GAN01144.1 - 0.17 12.1 0.0 9.1 6.6 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 GAN01144.1 - 0.23 11.5 0.9 14 5.7 0.0 2.9 2 1 1 3 3 2 0 AAA domain Fer4_4 PF12800.7 GAN01144.1 - 0.33 11.6 15.8 0.092 13.3 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 GAN01144.1 - 7.8 7.7 17.0 0.13 13.3 4.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 GAN01144.1 - 8.6 7.0 13.3 0.079 13.5 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Aminotran_1_2 PF00155.21 GAN01145.1 - 5.9e-77 259.3 0.0 1.3e-76 258.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Sec20 PF03908.13 GAN01145.1 - 1.5e-16 60.1 2.8 1.5e-16 60.1 2.8 2.4 2 0 0 2 2 2 1 Sec20 Cys_Met_Meta_PP PF01053.20 GAN01145.1 - 5.8e-06 25.1 0.0 1.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAN01145.1 - 8.3e-05 21.7 0.0 0.00076 18.5 0.0 2.4 1 1 1 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAN01145.1 - 0.0056 16.0 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Preseq_ALAS PF09029.10 GAN01145.1 - 0.018 15.5 7.7 0.034 14.6 5.3 2.6 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence DUF3405 PF11885.8 GAN01145.1 - 0.034 12.8 0.1 0.06 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) HOASN PF14515.6 GAN01145.1 - 0.11 13.0 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices FliT PF05400.13 GAN01145.1 - 2.9 8.8 6.4 1.3 9.9 2.2 2.6 2 1 1 3 3 3 0 Flagellar protein FliT Lactate_perm PF02652.14 GAN01149.1 - 2.9e-125 419.0 31.6 9e-75 252.4 20.7 2.1 2 0 0 2 2 2 2 L-lactate permease zf-C2H2 PF00096.26 GAN01150.1 - 1.7e-07 31.3 21.7 0.00018 21.7 4.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN01150.1 - 1.2e-05 25.5 4.9 1.2e-05 25.5 4.9 4.6 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN01150.1 - 6.8e-05 23.4 16.1 0.014 16.2 2.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN01150.1 - 0.00087 19.2 6.6 0.28 11.2 1.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN01150.1 - 0.047 14.0 3.1 5 7.5 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 GAN01150.1 - 0.097 12.4 0.4 0.15 11.7 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) UDPGT PF00201.18 GAN01151.1 - 1.4e-27 96.7 0.1 2.6e-27 95.8 0.1 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN01151.1 - 0.00054 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 GAN01151.1 - 0.084 12.9 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.6 GAN01151.1 - 0.089 12.0 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 1 tRNA-synt_2 PF00152.20 GAN01152.1 - 4.3e-91 305.3 0.0 6.4e-91 304.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAN01152.1 - 4.8e-09 36.1 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_L22 PF00237.19 GAN01152.1 - 0.00093 19.4 4.7 0.056 13.7 4.6 2.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e RR_TM4-6 PF06459.12 GAN01152.1 - 0.12 12.1 5.2 0.21 11.4 5.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EFTUD2 PF16004.5 GAN01152.1 - 0.96 10.0 7.0 2.6 8.7 7.0 1.7 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Nucleoporin_N PF08801.11 GAN01153.1 - 4.9e-38 131.0 4.1 8.1e-38 130.3 4.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 GAN01153.1 - 1.3e-22 80.4 2.1 2.1e-22 79.7 2.1 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal SNARE_assoc PF09335.11 GAN01154.1 - 1e-12 48.6 1.6 1e-12 48.6 1.6 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF2852 PF11014.8 GAN01154.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) HNH_5 PF14279.6 GAN01155.1 - 0.049 13.5 0.6 0.13 12.2 0.6 1.7 1 0 0 1 1 1 0 HNH endonuclease zf-LITAF-like PF10601.9 GAN01155.1 - 0.11 12.8 0.7 0.11 12.8 0.7 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain MatE PF01554.18 GAN01156.1 - 3e-56 189.5 29.1 2.6e-29 102.0 9.2 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAN01156.1 - 5.4e-07 29.8 13.0 5.4e-07 29.8 13.0 4.1 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain IGR PF09597.10 GAN01157.1 - 1.4e-25 89.1 0.1 1.8e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 IGR protein motif Rieske PF00355.26 GAN01158.1 - 1.4e-06 28.1 0.1 2.5e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SR-25 PF10500.9 GAN01158.1 - 0.00018 21.2 27.6 0.00088 19.0 6.2 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 GAN01158.1 - 0.00023 20.6 12.3 0.00029 20.3 12.3 1.1 1 0 0 1 1 1 1 BUD22 IMUP PF15761.5 GAN01158.1 - 0.00033 21.3 9.3 0.00033 21.3 9.3 2.3 2 0 0 2 2 1 1 Immortalisation up-regulated protein DUF4667 PF15700.5 GAN01158.1 - 0.071 13.2 12.2 0.14 12.2 12.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) CCDC106 PF15794.5 GAN01158.1 - 0.09 12.5 14.1 0.75 9.5 3.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Peroxin-13_N PF04088.13 GAN01158.1 - 0.35 11.1 2.8 2.1 8.6 0.2 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Spt20 PF12090.8 GAN01158.1 - 0.56 9.8 12.2 1.3 8.6 4.7 2.2 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 GAN01158.1 - 1.1 10.3 4.8 16 6.5 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PI3K_1B_p101 PF10486.9 GAN01158.1 - 1.1 6.9 7.1 0.96 7.2 0.9 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 GAN01158.1 - 1.7 8.3 6.2 4.6 6.9 0.8 2.3 2 0 0 2 2 2 0 FAM176 family DUF4519 PF15012.6 GAN01158.1 - 1.8 8.8 9.4 3.8 7.7 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF4614 PF15391.6 GAN01158.1 - 2.1 8.3 13.4 1.8 8.5 7.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Peptidase_S49_N PF08496.10 GAN01158.1 - 2.7 8.0 9.3 0.35 10.9 3.5 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Radial_spoke_3 PF06098.11 GAN01158.1 - 3.4 6.9 10.8 0.48 9.6 1.5 2.2 2 0 0 2 2 2 0 Radial spoke protein 3 HBM PF16591.5 GAN01159.1 - 0.003 17.0 6.7 0.005 16.3 6.7 1.4 1 0 0 1 1 1 1 Helical bimodular sensor domain CorA PF01544.18 GAN01159.1 - 3.4 6.9 8.0 4.6 6.5 8.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FA_desaturase PF00487.24 GAN01160.1 - 6.2e-34 118.0 23.7 6.2e-34 118.0 23.7 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAN01160.1 - 1.9e-15 56.8 0.0 4.5e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1374 PF07118.11 GAN01160.1 - 0.065 13.8 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) ABC2_membrane PF01061.24 GAN01162.1 - 1.7e-82 275.9 71.1 1.2e-48 165.3 21.8 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAN01162.1 - 8.5e-37 126.7 0.4 1.3e-19 71.0 0.0 3.6 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.12 GAN01162.1 - 4.8e-28 96.9 0.8 2.3e-23 81.9 0.0 4.5 4 1 1 5 5 4 2 CDR ABC transporter ABC_trans_N PF14510.6 GAN01162.1 - 1.7e-16 60.6 0.1 3.8e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAN01162.1 - 6.2e-09 35.4 50.2 3.7e-08 32.9 19.7 3.4 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 GAN01162.1 - 2.5e-05 24.7 0.0 0.0054 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAN01162.1 - 0.00013 22.0 0.3 0.0042 17.0 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 GAN01162.1 - 0.00081 19.3 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAN01162.1 - 0.004 16.8 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN01162.1 - 0.0072 16.5 0.0 0.52 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAN01162.1 - 0.0074 16.8 0.0 0.066 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAN01162.1 - 0.012 15.3 0.1 0.056 13.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 GAN01162.1 - 0.028 14.1 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAN01162.1 - 0.029 14.1 0.1 2.6 7.7 0.1 2.7 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 GAN01162.1 - 0.037 14.3 0.0 1.3 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAN01162.1 - 0.098 12.6 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 GAN01162.1 - 0.12 12.3 0.2 3 7.9 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DnaB_C PF03796.15 GAN01162.1 - 0.13 11.5 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 GAN01162.1 - 0.14 12.4 0.1 0.47 10.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAN01162.1 - 0.16 11.6 0.1 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 GAN01162.1 - 0.48 10.2 7.5 6.7 6.5 1.0 3.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Cas_Cas4 PF01930.17 GAN01163.1 - 0.11 12.6 0.6 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF83 DnaJ PF00226.31 GAN01165.1 - 5.1e-18 64.9 1.2 1.7e-17 63.3 1.2 2.0 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 GAN01165.1 - 2.3e-10 41.3 9.7 2.3e-10 41.3 9.7 3.9 4 0 0 4 4 4 1 Ribosome-associated complex head domain GerD PF17898.1 GAN01165.1 - 0.0058 16.6 4.6 0.021 14.8 4.6 1.9 1 0 0 1 1 1 1 Spore germination GerD central core domain TrmO_C PF18389.1 GAN01165.1 - 0.18 11.9 1.3 0.45 10.7 0.2 2.2 2 0 0 2 2 2 0 TrmO C-terminal domain Ion_trans PF00520.31 GAN01166.1 - 5e-05 22.7 11.4 6.3e-05 22.3 11.4 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GAN01166.1 - 0.0061 15.3 9.3 0.0062 15.3 7.8 1.6 1 1 1 2 2 2 1 Polycystin cation channel DUF805 PF05656.14 GAN01166.1 - 0.99 9.9 9.8 0.92 9.9 8.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) AC_N PF16214.5 GAN01166.1 - 2.2 7.3 4.6 2.6 7.1 4.6 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DPPIV_N PF00930.21 GAN01167.1 - 4.3e-103 344.8 8.4 6.2e-103 344.3 8.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAN01167.1 - 1.4e-49 168.4 3.7 2.6e-49 167.6 3.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAN01167.1 - 0.0016 18.1 3.8 0.0035 17.0 2.6 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 GAN01167.1 - 0.045 13.0 0.6 0.2 10.9 0.1 2.0 1 1 0 2 2 2 0 Serine aminopeptidase, S33 ANAPC4_WD40 PF12894.7 GAN01167.1 - 0.1 12.9 0.0 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S13 PF00416.22 GAN01168.1 - 8.9e-53 178.1 2.6 1.1e-52 177.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAN01168.1 - 0.011 14.5 0.0 0.013 14.3 0.0 1.2 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 GAN01168.1 - 0.058 12.4 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Nucleoporin_N PF08801.11 GAN01170.1 - 2.2e-50 171.7 1.1 3.1e-50 171.2 1.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 GAN01170.1 - 1.1e-07 31.0 7.0 3.4e-07 29.4 7.0 1.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Vps16_N PF04841.13 GAN01171.1 - 6.2e-110 367.8 0.0 8.4e-110 367.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 GAN01171.1 - 1.5e-97 326.5 3.1 2.2e-97 326.0 3.1 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 GAN01171.1 - 3e-05 24.2 0.4 0.11 12.8 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain lci PF12197.8 GAN01171.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein DUF1476 PF07345.11 GAN01171.1 - 0.13 12.7 1.9 0.41 11.0 0.0 2.7 3 0 0 3 3 3 0 ATPase inhibitor subunit zeta DASH_Hsk3 PF08227.11 GAN01172.1 - 0.0021 18.4 0.1 0.0028 18.0 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like AKNA PF12443.8 GAN01172.1 - 0.021 15.5 0.2 0.023 15.4 0.2 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor Kinetochor_Ybp2 PF08568.10 GAN01173.1 - 2.4e-21 75.9 11.7 7.7e-20 70.9 1.1 2.6 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin RPA_interact_N PF14766.6 GAN01173.1 - 0.0025 17.4 6.1 0.0047 16.5 6.1 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Ham1p_like PF01725.16 GAN01174.1 - 8.5e-57 192.1 0.0 9.7e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family APH PF01636.23 GAN01175.1 - 5.3e-41 141.1 0.0 7.1e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAN01175.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 GAN01175.1 - 0.01 15.5 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.14 GAN01175.1 - 0.019 14.2 0.0 0.62 9.2 0.0 2.2 1 1 1 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.20 GAN01175.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 GAN01175.1 - 0.24 10.2 0.0 1.9 7.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DHO_dh PF01180.21 GAN01177.1 - 1.4e-61 208.3 0.0 1.6e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase EamA PF00892.20 GAN01178.1 - 3.7e-10 40.1 22.7 4.4e-08 33.4 1.6 2.6 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAN01178.1 - 9.9e-09 34.8 2.1 1.4e-08 34.3 2.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 GAN01178.1 - 4.4e-08 32.8 6.2 3.2e-05 23.4 0.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 GAN01178.1 - 1.2e-07 31.1 1.5 2.3e-05 23.5 0.0 3.0 3 0 0 3 3 3 2 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 GAN01178.1 - 2e-06 27.2 10.7 3.1e-06 26.6 10.7 1.2 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 GAN01178.1 - 0.00036 19.9 0.4 0.00036 19.9 0.4 2.9 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 GAN01178.1 - 0.021 14.4 13.5 0.11 12.0 13.5 1.9 1 1 0 1 1 1 0 Solute carrier family 35 HEPN_SAV_6107 PF18726.1 GAN01178.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 SAV_6107-like HEPN HMG_box PF00505.19 GAN01179.1 - 2.6e-19 69.4 5.2 2.6e-19 69.4 5.2 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN01179.1 - 2.7e-12 47.1 4.5 2.7e-12 47.1 4.5 2.0 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 GAN01179.1 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain MlaC PF05494.12 GAN01179.1 - 0.017 14.9 1.1 0.029 14.1 1.1 1.3 1 0 0 1 1 1 0 MlaC protein DUF4692 PF15763.5 GAN01179.1 - 0.11 12.9 12.9 0.24 11.8 12.9 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Gluconate_2-dh3 PF13618.6 GAN01179.1 - 0.2 11.9 4.8 0.44 10.8 4.6 1.8 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Cwf_Cwc_15 PF04889.12 GAN01179.1 - 0.53 10.0 23.3 0.065 13.0 18.3 1.7 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 GAN01179.1 - 4.4 5.0 11.8 5.1 4.7 11.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Borrelia_P83 PF05262.11 GAN01179.1 - 5.6 5.3 18.8 6.7 5.1 18.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Macoilin PF09726.9 GAN01179.1 - 7.1 5.1 16.4 7.2 5.0 16.4 1.1 1 0 0 1 1 1 0 Macoilin family CENP-B_dimeris PF09026.10 GAN01180.1 - 0.9 10.0 10.6 0.24 11.8 5.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mito_carr PF00153.27 GAN01181.1 - 5.5e-63 208.9 2.7 5.5e-20 71.1 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 GAN01181.1 - 0.028 14.5 0.1 27 4.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) CHIPS PF11434.8 GAN01181.1 - 0.11 12.4 0.2 1.9 8.3 0.0 2.2 1 1 1 2 2 2 0 Chemotaxis-inhibiting protein CHIPS PolyA_pol PF01743.20 GAN01182.1 - 8.6e-29 100.5 0.0 1.9e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAN01182.1 - 2.1e-07 30.6 0.2 6.2e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A FDF PF09532.10 GAN01183.1 - 0.14 13.1 2.4 1.7 9.5 0.2 2.5 2 0 0 2 2 2 0 FDF domain SWIM PF04434.17 GAN01184.1 - 0.0014 18.2 1.2 0.0014 18.2 1.2 1.9 2 0 0 2 2 2 1 SWIM zinc finger TMEM171 PF15471.6 GAN01184.1 - 8.2 5.3 8.9 13 4.7 8.9 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 PNP_UDP_1 PF01048.20 GAN01185.1 - 2.4e-43 148.1 2.0 3.9e-43 147.4 2.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily p450 PF00067.22 GAN01186.1 - 1.3e-83 281.3 0.0 1.6e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_48 PF02011.15 GAN01186.1 - 0.16 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 SNF2_N PF00176.23 GAN01187.1 - 2.5e-51 174.4 0.0 2.2e-42 145.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN01187.1 - 2.6e-13 50.3 0.0 4.4e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN01187.1 - 5e-09 36.4 0.1 1.2e-08 35.1 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAN01187.1 - 1.2e-05 25.1 0.1 3.1e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 GAN01187.1 - 0.00071 19.4 13.4 0.00071 19.4 13.4 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN01187.1 - 0.00075 19.3 11.2 0.00075 19.3 11.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SR-25 PF10500.9 GAN01187.1 - 0.034 13.8 0.2 0.034 13.8 0.2 2.8 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein zf-RING_UBOX PF13445.6 GAN01187.1 - 0.035 14.1 9.1 0.13 12.3 9.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_14 PF17978.1 GAN01187.1 - 0.047 14.1 4.1 0.12 12.8 4.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS91 PF14319.6 GAN01187.1 - 2.1 8.4 13.3 5.2 7.2 2.6 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain FlhC PF05280.11 GAN01187.1 - 4.7 6.9 9.5 5.3 6.7 0.9 2.8 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) AMP-binding PF00501.28 GAN01188.1 - 3.1e-99 332.5 0.0 4e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN01188.1 - 0.091 13.7 0.0 0.25 12.4 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain CCDC53 PF10152.9 GAN01189.1 - 2.3 8.6 10.3 16 5.9 10.3 2.4 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex V-ATPase_G PF03179.15 GAN01190.1 - 7.8e-30 103.5 15.4 8.9e-30 103.3 15.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 GAN01190.1 - 0.02 15.3 15.5 0.04 14.3 15.5 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 GAN01190.1 - 0.022 14.8 8.5 0.022 14.8 8.5 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) AcylCoA_dehyd_C PF12186.8 GAN01190.1 - 0.024 14.8 1.3 0.024 14.8 1.3 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal CdiI_2 PF18593.1 GAN01190.1 - 0.048 14.3 2.5 0.42 11.3 0.4 2.1 1 1 1 2 2 2 0 CdiI immunity protein Strumpellin PF10266.9 GAN01190.1 - 0.082 10.6 4.0 0.089 10.5 4.0 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin DUF883 PF05957.13 GAN01190.1 - 0.18 12.4 11.4 0.2 12.3 3.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2115 PF09888.9 GAN01190.1 - 0.27 11.7 5.2 0.35 11.4 5.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) ZYG-11_interact PF05884.12 GAN01190.1 - 0.42 10.0 6.0 2.1 7.7 6.0 1.8 1 1 0 1 1 1 0 Interactor of ZYG-11 Seryl_tRNA_N PF02403.22 GAN01190.1 - 0.54 10.5 11.5 1.5 9.1 11.5 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PEP-utilisers_N PF05524.13 GAN01190.1 - 1.4 9.1 9.4 3.3 7.9 9.4 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4407 PF14362.6 GAN01190.1 - 2.4 7.4 10.6 2.8 7.2 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2937 PF11157.8 GAN01190.1 - 6.1 6.5 6.2 15 5.2 6.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Ribosomal_L3 PF00297.22 GAN01191.1 - 2.6e-30 105.6 1.4 3e-30 105.4 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PSP1 PF04468.12 GAN01192.1 - 1.6e-35 121.2 4.7 1.6e-35 121.2 4.7 1.9 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Gpi1 PF05024.15 GAN01193.1 - 7e-72 241.4 12.2 1.7e-71 240.2 12.2 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) T5orf172 PF10544.9 GAN01194.1 - 1.3e-15 57.8 0.0 1.3e-15 57.8 0.0 3.2 2 1 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 GAN01194.1 - 3.4e-13 50.1 1.1 8.1e-13 48.9 0.1 2.1 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 BNIP2 PF12496.8 GAN01194.1 - 0.066 13.6 2.9 8.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Totivirus_coat PF05518.11 GAN01194.1 - 0.48 8.4 3.7 0.73 7.8 3.7 1.2 1 0 0 1 1 1 0 Totivirus coat protein Rubredoxin_2 PF18073.1 GAN01194.1 - 2.5 7.9 4.7 0.3 10.8 0.6 1.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain Pro_dh PF01619.18 GAN01195.1 - 4.6e-72 243.1 4.1 4.6e-72 243.1 4.1 2.2 2 1 0 2 2 2 1 Proline dehydrogenase DUF2972 PF11186.8 GAN01196.1 - 0.011 15.7 6.9 0.014 15.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) MFS_1 PF07690.16 GAN01197.1 - 2.6e-18 66.1 40.1 2.6e-18 66.1 40.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN01197.1 - 0.00022 19.9 34.4 0.0071 15.0 7.5 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein MWFE PF15879.5 GAN01197.1 - 0.14 12.4 0.3 16 5.7 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit RVT_1 PF00078.27 GAN01199.1 - 2.3e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GAN01200.1 - 2.2e-06 28.3 0.1 2.2e-06 28.3 0.1 2.6 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 GAN01200.1 - 0.00071 19.5 3.1 0.00071 19.5 3.1 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 GAN01200.1 - 0.097 12.5 5.5 0.25 11.2 5.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Carn_acyltransf PF00755.20 GAN01202.1 - 6.9e-208 692.0 0.0 7.8e-208 691.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TPR_1 PF00515.28 GAN01203.1 - 2.2e-26 90.5 37.1 3.2e-05 23.6 0.1 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAN01203.1 - 3.1e-25 86.2 34.7 0.00012 21.9 0.1 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN01203.1 - 2e-20 72.8 33.0 1.1e-18 67.2 0.8 6.0 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAN01203.1 - 2.6e-15 55.3 30.3 0.0013 18.8 0.1 9.3 9 1 0 9 9 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAN01203.1 - 3.3e-15 56.1 24.4 0.006 16.8 0.2 8.5 6 3 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAN01203.1 - 3.4e-14 53.2 16.4 8.3e-06 26.3 0.8 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN01203.1 - 8.9e-12 44.8 5.7 0.019 15.8 0.1 7.0 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN01203.1 - 7.9e-09 35.9 16.6 0.0037 17.8 1.1 6.5 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAN01203.1 - 3.7e-08 32.8 15.7 0.0036 17.2 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN01203.1 - 7.2e-08 32.0 17.5 0.005 16.5 0.1 6.9 6 1 1 7 7 7 3 TPR repeat TPR_9 PF13371.6 GAN01203.1 - 1.1e-07 31.9 3.9 0.006 16.7 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAN01203.1 - 3.9e-07 30.3 21.6 0.02 15.5 1.2 8.6 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAN01203.1 - 4.9e-07 29.2 9.3 1.2 8.3 0.3 5.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAN01203.1 - 1.4e-05 25.3 3.4 1.4 9.3 0.2 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN01203.1 - 0.00016 21.8 17.7 0.00055 20.1 0.1 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN01203.1 - 0.00072 19.0 4.9 0.11 11.9 0.1 4.5 3 2 1 5 5 5 1 MalT-like TPR region TPR_10 PF13374.6 GAN01203.1 - 0.00088 19.1 19.8 0.024 14.5 0.1 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAN01203.1 - 0.0019 18.2 23.8 0.065 13.3 0.9 6.8 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 GAN01203.1 - 0.0053 16.2 5.5 3.3 7.0 0.4 4.2 4 0 0 4 4 4 1 Coatomer epsilon subunit B12-binding_2 PF02607.17 GAN01203.1 - 0.041 14.3 0.0 0.55 10.7 0.0 2.7 3 0 0 3 3 2 0 B12 binding domain TPR_21 PF09976.9 GAN01203.1 - 0.11 12.2 3.3 5.5 6.7 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain PPR PF01535.20 GAN01203.1 - 1 9.7 4.7 54 4.3 0.0 5.0 5 0 0 5 5 4 0 PPR repeat MFS_1 PF07690.16 GAN01204.1 - 3e-31 108.7 16.7 3e-31 108.7 16.7 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN01204.1 - 2.1e-08 33.5 7.9 2.1e-08 33.5 7.9 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 GAN01204.1 - 6.1e-05 22.5 9.1 0.00021 20.7 4.1 3.8 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sre PF03125.18 GAN01204.1 - 0.063 12.4 4.5 0.47 9.6 0.1 2.8 3 0 0 3 3 3 0 C. elegans Sre G protein-coupled chemoreceptor OAD_gamma PF04277.13 GAN01204.1 - 0.35 11.5 1.3 5.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain SieB PF14163.6 GAN01204.1 - 2.1 7.8 8.0 0.47 9.9 3.3 2.3 3 0 0 3 3 3 0 Super-infection exclusion protein B SUI1 PF01253.22 GAN01205.1 - 3.7e-22 78.7 0.4 8e-22 77.6 0.1 1.7 1 1 0 1 1 1 1 Translation initiation factor SUI1 BAR_2 PF10455.9 GAN01205.1 - 0.035 13.3 4.1 0.046 12.8 4.1 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Acylphosphatase PF00708.18 GAN01205.1 - 0.055 13.9 0.8 0.14 12.5 0.0 2.0 2 1 0 2 2 2 0 Acylphosphatase Syntaxin PF00804.25 GAN01206.1 - 7.9e-37 126.9 19.6 1.3e-36 126.2 19.6 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAN01206.1 - 5e-14 52.0 2.8 5.5e-14 51.9 0.6 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 GAN01206.1 - 2.6e-06 27.7 7.4 2.6e-06 27.7 7.4 2.6 2 1 1 3 3 3 1 Syntaxin-like protein Vac_Fusion PF02346.16 GAN01206.1 - 0.0014 18.2 0.8 0.0014 18.2 0.8 3.2 3 1 1 4 4 4 1 Chordopoxvirus multifunctional envelope protein A27 YfdX PF10938.8 GAN01206.1 - 1.2 9.1 7.1 1.1 9.2 0.4 2.5 3 0 0 3 3 3 0 YfdX protein MCPsignal PF00015.21 GAN01206.1 - 2.5 7.9 18.1 0.048 13.5 3.9 3.3 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4094 PF13334.6 GAN01206.1 - 3.6 8.1 10.3 0.076 13.4 1.2 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) Neur_chan_memb PF02932.16 GAN01206.1 - 5.1 7.1 7.0 0.35 10.9 1.3 1.9 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Fib_alpha PF08702.10 GAN01206.1 - 7.2 6.8 24.8 13 6.0 10.4 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SapB_1 PF05184.15 GAN01206.1 - 8.8 6.5 7.2 3.9 7.6 0.1 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 LIM PF00412.22 GAN01207.1 - 1.1e-41 140.8 50.9 1.6e-11 44.3 6.2 4.9 5 0 0 5 5 5 4 LIM domain Fer4_21 PF14697.6 GAN01207.1 - 0.062 13.5 0.6 0.062 13.5 0.6 5.1 4 3 1 5 5 5 0 4Fe-4S dicluster domain GET2 PF08690.10 GAN01207.1 - 2.4 7.8 5.5 3.7 7.2 5.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 NTP_transferase PF00483.23 GAN01208.1 - 1.9e-27 96.4 0.0 2.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAN01208.1 - 1.6e-07 30.8 11.9 0.00061 19.4 0.8 3.8 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAN01208.1 - 3e-07 30.9 0.0 5.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NADH-UOR_E PF16514.5 GAN01208.1 - 0.036 14.4 0.1 0.09 13.1 0.1 1.6 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E Fucokinase PF07959.12 GAN01208.1 - 0.044 12.7 0.7 0.088 11.7 0.2 1.7 2 0 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 GAN01208.1 - 0.049 11.8 0.4 0.071 11.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GAN01208.1 - 0.096 12.5 2.4 0.43 10.4 1.1 2.6 1 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase CK_II_beta PF01214.18 GAN01209.1 - 4e-79 264.7 0.0 5.5e-79 264.2 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Complex1_LYR PF05347.15 GAN01209.1 - 0.027 14.5 0.5 0.064 13.3 0.5 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) CxC5 PF18718.1 GAN01209.1 - 0.033 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Tox-URI2 PF15653.6 GAN01209.1 - 0.069 13.4 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 URI fold toxin 2 AP_endonuc_2 PF01261.24 GAN01209.1 - 0.2 11.1 0.2 0.34 10.3 0.0 1.4 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel CAF1A PF12253.8 GAN01210.1 - 1.4e-21 76.5 4.3 2.8e-21 75.5 4.3 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A DUF3402 PF11882.8 GAN01211.1 - 4.1e-92 309.7 11.7 3.9e-52 177.9 5.3 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 GAN01211.1 - 3.1e-44 151.3 3.5 8e-44 150.0 3.5 1.7 1 0 0 1 1 1 1 N1221-like protein Pkinase PF00069.25 GAN01212.1 - 6.3e-06 25.7 0.0 7.5e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01212.1 - 0.0022 17.4 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3439 PF11921.8 GAN01213.1 - 0.17 11.9 6.1 0.26 11.2 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAN01213.1 - 4.4 7.3 15.0 6.5 6.7 15.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein UPF0697 PF15117.6 GAN01214.1 - 3.4 7.8 13.7 0.87 9.7 2.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 Myb_DNA-bind_6 PF13921.6 GAN01215.1 - 0.00024 21.3 0.0 0.00054 20.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN01215.1 - 0.002 18.3 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ICL PF00463.21 GAN01215.1 - 0.083 11.4 1.3 0.11 10.9 1.3 1.1 1 0 0 1 1 1 0 Isocitrate lyase family RraA-like PF03737.15 GAN01216.1 - 1.6e-34 119.2 0.0 2.1e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Fcf2 PF08698.11 GAN01218.1 - 1.7e-37 127.7 3.7 1.7e-37 127.7 3.7 2.6 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing PP28 PF10252.9 GAN01218.1 - 0.015 15.7 3.5 0.015 15.7 3.5 4.1 4 1 0 4 4 4 0 Casein kinase substrate phosphoprotein PP28 Asp4 PF16996.5 GAN01218.1 - 0.25 11.2 1.0 6.4 6.7 0.4 2.5 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 Sporozoite_P67 PF05642.11 GAN01218.1 - 1.1 7.3 12.2 1.7 6.6 12.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rhomboid PF01694.22 GAN01219.1 - 0.039 14.0 7.5 0.077 13.0 7.5 1.5 1 0 0 1 1 1 0 Rhomboid family LRR_6 PF13516.6 GAN01220.1 - 7.2e-15 53.7 28.1 0.19 11.9 0.0 10.3 11 0 0 11 11 11 6 Leucine Rich repeat LRR_8 PF13855.6 GAN01220.1 - 1e-07 31.6 22.6 4.6e-05 23.1 0.7 5.1 4 1 0 4 4 4 3 Leucine rich repeat UBX PF00789.20 GAN01220.1 - 5.3e-07 29.7 0.1 1.5e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 UBX domain LRR_4 PF12799.7 GAN01220.1 - 1.4e-05 25.3 33.9 0.069 13.6 2.5 7.8 5 3 0 7 7 7 3 Leucine Rich repeats (2 copies) ETF PF01012.21 GAN01221.1 - 6.4e-50 169.6 1.9 8.2e-50 169.2 1.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Aldo_ket_red PF00248.21 GAN01222.1 - 2e-40 138.8 0.0 2.4e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RVT PF13966.6 GAN01223.1 - 2.7e-08 34.4 4.1 3.8e-08 33.9 4.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GF_recep_IV PF14843.6 GAN01223.1 - 0.025 14.4 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV DUF1574 PF07611.11 GAN01223.1 - 0.026 13.9 0.9 0.033 13.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) An_peroxidase PF03098.15 GAN01223.1 - 0.035 12.7 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase Mito_carr PF00153.27 GAN01224.1 - 7.5e-63 208.5 0.2 4.9e-21 74.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Forkhead PF00250.18 GAN01225.1 - 4e-31 107.1 0.0 9.8e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain RAB3GAP2_N PF14655.6 GAN01225.1 - 0.023 14.0 1.9 0.057 12.7 1.9 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RAP1 PF07218.11 GAN01225.1 - 10 4.3 8.2 13 3.9 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) bZIP_1 PF00170.21 GAN01226.1 - 3.4e-10 39.9 14.4 6.1e-10 39.1 14.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN01226.1 - 4.7e-06 26.6 13.5 7.7e-06 25.9 13.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DMPK_coil PF08826.10 GAN01226.1 - 0.0025 17.9 2.4 0.0045 17.1 2.4 1.4 1 0 0 1 1 1 1 DMPK coiled coil domain like bZIP_Maf PF03131.17 GAN01226.1 - 0.0037 17.7 8.0 0.0067 16.9 8.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor pRN1_helical PF13010.6 GAN01226.1 - 0.056 13.4 0.1 0.099 12.6 0.1 1.3 1 0 0 1 1 1 0 Primase helical domain Hist_deacetyl PF00850.19 GAN01227.1 - 3.1e-57 194.4 0.0 4.2e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain AMP-binding PF00501.28 GAN01228.1 - 1.2e-98 330.5 0.0 1.5e-98 330.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN01228.1 - 3.5e-13 50.3 0.9 1.8e-12 48.1 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4668 PF15701.5 GAN01228.1 - 0.18 11.7 0.2 0.29 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Cid2 PF09774.9 GAN01229.1 - 5.3e-20 72.4 7.5 8.7e-18 65.3 7.5 2.4 1 1 0 1 1 1 1 Caffeine-induced death protein 2 LMWSLP_N PF12211.8 GAN01229.1 - 0.081 12.5 0.1 0.092 12.4 0.1 1.1 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal PRANC PF09372.10 GAN01229.1 - 0.088 13.1 0.3 0.33 11.3 0.1 1.9 1 1 1 2 2 2 0 PRANC domain ATP-synt_ab_C PF00306.27 GAN01230.1 - 6.4e-14 52.4 0.0 7.1e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 GAN01231.1 - 6.3e-05 23.4 0.0 9.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PC-Esterase PF13839.6 GAN01232.1 - 3.3e-30 105.8 0.0 5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL PF00657.22 GAN01232.1 - 0.032 14.2 0.0 1 9.3 0.0 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Erp_C PF06780.11 GAN01232.1 - 0.032 14.2 0.0 0.095 12.7 0.0 1.7 2 0 0 2 2 2 0 Erp protein C-terminus PMR5N PF14416.6 GAN01232.1 - 0.31 11.4 6.6 0.36 11.2 2.7 2.7 2 1 0 2 2 2 0 PMR5 N terminal Domain ArAE_2 PF10334.9 GAN01233.1 - 4.1e-17 62.8 0.0 8.8e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 GAN01233.1 - 1.3e-11 44.2 27.5 5.5e-09 35.6 8.2 3.9 3 1 0 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAN01233.1 - 1.7e-10 41.1 21.1 1.7e-10 41.1 21.1 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 GAN01233.1 - 0.00087 18.2 5.1 0.00087 18.2 5.1 1.8 2 0 0 2 2 2 1 Aluminium activated malate transporter Cauli_AT PF03233.13 GAN01233.1 - 0.037 14.0 0.2 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Aphid transmission protein Dynactin_p22 PF07426.11 GAN01233.1 - 3.6 7.4 11.3 5.6 6.8 0.3 3.3 3 0 0 3 3 3 0 Dynactin subunit p22 PALP PF00291.25 GAN01234.1 - 4.3e-73 246.3 0.1 5.3e-73 246.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Vps5 PF09325.10 GAN01235.1 - 6.4e-19 68.4 12.6 1.2e-10 41.4 2.7 2.2 1 1 1 2 2 2 2 Vps5 C terminal like Rpr2 PF04032.16 GAN01235.1 - 4.3e-15 55.8 0.2 2.3e-14 53.4 0.0 2.3 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PX PF00787.24 GAN01235.1 - 5.2e-15 55.4 0.1 3.5e-14 52.8 0.1 2.4 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 GAN01235.1 - 0.0025 17.6 11.1 0.028 14.1 0.6 2.4 2 0 0 2 2 2 2 BAR domain of APPL family Sec34 PF04136.15 GAN01235.1 - 0.026 14.4 0.1 0.026 14.4 0.1 2.6 2 1 1 3 3 3 0 Sec34-like family NPV_P10 PF05531.12 GAN01235.1 - 0.13 12.7 0.5 9.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 GAN01235.1 - 0.19 12.2 8.7 1.9 9.0 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF1664 PF07889.12 GAN01235.1 - 0.31 11.1 5.1 3.2 7.8 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 GAN01235.1 - 0.54 10.7 3.9 0.86 10.1 0.4 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MapZ_EC1 PF18041.1 GAN01235.1 - 1.2 9.4 9.0 0.46 10.7 0.4 2.9 3 0 0 3 3 3 0 MapZ extracellular domain 1 CLZ PF16526.5 GAN01235.1 - 4.6 7.7 7.4 9.7 6.6 0.7 2.9 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 GAN01235.1 - 6.9 7.0 12.6 0.88 9.9 0.8 3.7 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG22 PF11700.8 GAN01236.1 - 2e-90 303.8 22.4 1.1e-89 301.3 22.4 1.8 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAN01236.1 - 2.2e-12 46.6 42.9 1.3e-07 30.9 8.4 3.2 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2730 PF10805.8 GAN01236.1 - 0.046 13.8 0.2 0.13 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) E1-E2_ATPase PF00122.20 GAN01236.1 - 1.4 8.4 3.6 1.6 8.2 1.4 2.2 2 0 0 2 2 2 0 E1-E2 ATPase SWIRM PF04433.17 GAN01237.1 - 2.5e-09 37.3 0.0 5.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Anp1 PF03452.14 GAN01238.1 - 5.5e-95 317.7 0.7 6.9e-95 317.4 0.7 1.0 1 0 0 1 1 1 1 Anp1 SgrT PF15894.5 GAN01238.1 - 0.1 12.6 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT Avl9 PF09794.9 GAN01239.1 - 2e-139 464.5 0.0 2e-139 464.5 0.0 1.6 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 GAN01239.1 - 3.9e-12 46.1 0.1 1e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 GAN01239.1 - 1.5e-07 31.3 6.9 0.00041 20.0 1.0 4.4 3 2 2 5 5 5 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 GAN01239.1 - 0.016 15.1 2.9 1 9.3 0.2 3.9 4 1 0 4 4 4 0 DENN (AEX-3) domain FA_desaturase PF00487.24 GAN01240.1 - 0.015 15.1 0.4 0.015 15.1 0.4 1.9 2 0 0 2 2 2 0 Fatty acid desaturase MFS_1 PF07690.16 GAN01241.1 - 0.032 13.2 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2140 PF09911.9 GAN01241.1 - 0.035 13.7 0.3 0.21 11.1 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) MLANA PF14991.6 GAN01241.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein melan-A FAM72 PF14976.6 GAN01242.1 - 9.2e-28 97.2 0.2 1.4e-27 96.6 0.2 1.3 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 GAN01242.1 - 0.00092 19.4 2.2 0.00092 19.4 2.2 1.9 2 1 1 3 3 3 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 GAN01242.1 - 0.083 12.4 1.9 0.41 10.2 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_6 PF14599.6 GAN01242.1 - 0.12 12.4 4.0 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon HECT_2 PF09814.9 GAN01242.1 - 0.2 10.5 2.9 5.4 5.8 0.6 2.1 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_12 PF11331.8 GAN01242.1 - 0.91 9.4 3.6 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain Zn_clus PF00172.18 GAN01243.1 - 1.4e-07 31.5 8.7 3.8e-07 30.1 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bromodomain PF00439.25 GAN01244.1 - 1.1e-22 79.8 1.1 2e-22 79.0 0.1 2.0 2 0 0 2 2 2 1 Bromodomain DUF3512 PF12024.8 GAN01244.1 - 0.0045 16.5 0.0 0.0045 16.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) TFIID-18kDa PF02269.16 GAN01245.1 - 7.1e-31 106.1 0.2 1.9e-30 104.7 0.2 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF1314 PF07013.11 GAN01245.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) NUDE_C PF04880.13 GAN01245.1 - 1.8 9.0 8.3 3.5 8.1 3.4 2.3 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region HlyIII PF03006.20 GAN01246.1 - 6.3e-62 209.2 21.1 8.4e-62 208.8 21.1 1.2 1 0 0 1 1 1 1 Haemolysin-III related Glyco_trans_1_2 PF13524.6 GAN01246.1 - 0.032 14.6 1.0 0.35 11.3 0.1 2.9 3 0 0 3 3 3 0 Glycosyl transferases group 1 HSCB_C PF07743.13 GAN01246.1 - 0.093 13.2 0.4 0.093 13.2 0.4 1.9 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4446 PF14584.6 GAN01246.1 - 0.16 11.9 0.8 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CBS PF00571.28 GAN01247.1 - 1.1e-27 96.2 3.8 3.8e-08 33.7 0.0 4.9 4 1 0 4 4 4 4 CBS domain CoA_binding_2 PF13380.6 GAN01247.1 - 0.027 15.0 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain DUF5035 PF16438.5 GAN01247.1 - 0.094 12.6 0.7 8.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5035) ATP12 PF07542.11 GAN01248.1 - 9.9e-41 138.8 1.1 1.9e-40 137.9 1.1 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Sds3 PF08598.11 GAN01249.1 - 1.5e-10 41.4 10.0 1.5e-10 41.4 10.0 2.0 1 1 1 2 2 2 1 Sds3-like YlqD PF11068.8 GAN01249.1 - 0.011 16.0 0.4 0.011 16.0 0.4 3.3 3 1 1 4 4 4 0 YlqD protein FAM176 PF14851.6 GAN01249.1 - 1.9 8.1 5.6 5.4 6.7 5.6 1.9 1 0 0 1 1 1 0 FAM176 family HSF_DNA-bind PF00447.17 GAN01250.1 - 6.1e-33 113.3 2.5 6.1e-33 113.3 2.5 2.8 3 1 0 3 3 3 1 HSF-type DNA-binding ATG16 PF08614.11 GAN01250.1 - 0.0019 18.4 0.9 0.0019 18.4 0.9 2.7 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 GAN01250.1 - 0.19 10.6 3.4 0.23 10.3 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cob_adeno_trans PF01923.18 GAN01250.1 - 3 8.0 4.8 0.5 10.5 0.8 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF2203 PF09969.9 GAN01250.1 - 8.7 7.1 7.0 2.9 8.6 1.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) LSM PF01423.22 GAN01251.1 - 4.5e-17 61.5 0.0 6.6e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAN01251.1 - 0.024 14.7 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain KTSC PF13619.6 GAN01251.1 - 0.22 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 KTSC domain Abhydrolase_3 PF07859.13 GAN01252.1 - 4.6e-66 222.7 0.1 5.6e-66 222.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN01252.1 - 5.7e-07 28.7 0.0 9.6e-07 28.0 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 GAN01252.1 - 9.3e-05 21.5 0.3 0.0014 17.6 0.3 2.1 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 GAN01252.1 - 0.0027 16.6 0.1 0.0041 16.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 GAN01252.1 - 0.0086 14.8 0.0 0.017 13.8 0.0 1.5 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.11 GAN01252.1 - 0.019 14.0 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 GAN01252.1 - 0.072 12.7 0.3 13 5.3 0.1 2.2 1 1 0 2 2 2 0 Putative esterase PAF-AH_p_II PF03403.13 GAN01252.1 - 0.21 10.1 0.4 0.93 7.9 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Colicin PF01024.19 GAN01253.1 - 0.088 12.7 1.8 1.7 8.5 0.3 3.0 3 0 0 3 3 3 0 Colicin pore forming domain Mitofilin PF09731.9 GAN01254.1 - 2.4e-90 304.2 39.3 6.7e-78 263.1 39.2 2.3 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Glucodextran_B PF09136.10 GAN01254.1 - 0.0059 17.0 3.5 0.017 15.5 3.5 1.8 1 0 0 1 1 1 1 Glucodextranase, domain B APG6_N PF17675.1 GAN01254.1 - 0.0078 16.7 3.7 0.0078 16.7 3.7 3.2 2 1 0 3 3 3 1 Apg6 coiled-coil region Nsp1_C PF05064.13 GAN01254.1 - 0.025 14.4 0.8 0.025 14.4 0.8 3.2 3 0 0 3 3 3 0 Nsp1-like C-terminal region SOGA PF11365.8 GAN01254.1 - 0.078 14.1 7.4 0.11 13.6 3.9 3.1 2 1 0 2 2 2 0 Protein SOGA LUC7 PF03194.15 GAN01254.1 - 0.94 9.1 12.2 1.5 8.4 11.3 1.8 1 1 0 1 1 1 0 LUC7 N_terminus G6PD_C PF02781.16 GAN01255.1 - 2.4e-111 371.6 0.0 3.9e-111 370.9 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAN01255.1 - 3.1e-58 197.3 0.5 1e-57 195.6 0.2 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain PAS PF00989.25 GAN01256.1 - 8.3e-12 45.1 0.1 5.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 GAN01256.1 - 1.2e-11 44.7 0.0 8.4e-11 42.0 0.1 2.1 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 GAN01256.1 - 3.4e-10 40.1 0.0 2e-09 37.5 0.0 2.1 2 1 1 3 3 3 1 PAS domain PAS_4 PF08448.10 GAN01256.1 - 6e-07 29.7 0.0 0.0028 17.9 0.0 2.5 2 1 0 2 2 2 2 PAS fold PAS_2 PF08446.11 GAN01256.1 - 8.4e-05 23.2 0.0 0.011 16.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 GAN01256.1 - 0.00014 22.1 0.0 0.0048 17.1 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_12 PF18095.1 GAN01256.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain CRIM PF16978.5 GAN01256.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain E1-E2_ATPase PF00122.20 GAN01257.1 - 1.1e-31 109.8 4.2 7.7e-27 94.0 0.3 4.6 3 2 2 5 5 5 2 E1-E2 ATPase Cation_ATPase PF13246.6 GAN01257.1 - 1.9e-20 72.7 0.0 3.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN01257.1 - 1.9e-20 74.0 0.1 2.3e-15 57.5 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 GAN01257.1 - 8e-19 68.0 0.6 1.8e-18 66.9 0.6 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 GAN01257.1 - 1.8e-13 49.9 0.0 5.6e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus zf-C2H2 PF00096.26 GAN01258.1 - 1.3e-09 38.0 14.5 3.3e-05 24.1 1.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN01258.1 - 1.6e-05 25.1 0.4 1.6e-05 25.1 0.4 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN01258.1 - 0.00011 22.7 7.1 0.0028 18.4 1.2 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 GAN01258.1 - 0.00043 20.5 0.5 0.0012 19.0 0.5 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 GAN01258.1 - 0.0029 17.8 1.9 0.031 14.6 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAN01258.1 - 0.023 14.7 0.8 0.023 14.7 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAN01258.1 - 0.035 14.0 2.3 0.26 11.2 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 GAN01258.1 - 3.6 7.6 6.9 0.6 10.1 1.4 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF3336 PF11815.8 GAN01259.1 - 9.8e-44 148.4 6.6 1.9e-43 147.5 6.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAN01259.1 - 9.5e-17 61.8 0.7 7.3e-16 59.0 0.1 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase VTC PF09359.10 GAN01260.1 - 1.3e-102 342.9 0.1 1.9e-102 342.4 0.1 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 GAN01260.1 - 2.9e-16 60.4 10.8 9.1e-06 25.8 0.0 3.8 5 0 0 5 5 5 3 SPX domain DUF202 PF02656.15 GAN01260.1 - 5.7e-14 52.3 0.2 1.1e-13 51.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) ECH_1 PF00378.20 GAN01261.1 - 1.6e-23 83.3 0.0 2.1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAN01261.1 - 0.00064 19.7 0.0 0.049 13.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 ECH_2 PF16113.5 GAN01261.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PFO_beta_C PF12367.8 GAN01261.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal bZIP_1 PF00170.21 GAN01262.1 - 6e-07 29.5 21.8 0.00014 21.9 21.8 2.8 1 1 0 1 1 1 1 bZIP transcription factor DUF812 PF05667.11 GAN01262.1 - 0.01 14.8 12.0 0.64 8.8 12.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Chibby PF14645.6 GAN01262.1 - 0.036 14.5 3.3 0.14 12.6 3.3 2.0 1 0 0 1 1 1 0 Chibby family ZapB PF06005.12 GAN01262.1 - 0.041 14.3 5.4 0.041 14.3 5.4 3.0 2 1 1 3 3 3 0 Cell division protein ZapB bZIP_2 PF07716.15 GAN01262.1 - 0.22 11.6 26.2 0.061 13.4 8.6 2.8 2 1 1 3 3 3 0 Basic region leucine zipper YabA PF06156.13 GAN01262.1 - 0.23 12.1 6.5 0.6 10.8 6.5 1.7 1 0 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 GAN01262.1 - 0.42 8.5 4.6 0.6 7.9 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 GAN01262.1 - 1.4 8.8 12.8 6.1 6.7 12.8 2.1 1 1 0 1 1 1 0 Septum formation initiator DDRGK PF09756.9 GAN01262.1 - 4.2 6.9 17.4 7.5 6.1 17.4 1.3 1 0 0 1 1 1 0 DDRGK domain Ytp1 PF10355.9 GAN01263.1 - 1e-14 54.4 4.3 1e-14 54.4 4.3 3.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) Ni_hydr_CYTB PF01292.20 GAN01263.1 - 8e-07 28.8 5.4 0.0089 15.6 0.0 3.0 2 1 0 3 3 3 2 Prokaryotic cytochrome b561 DUF3474 PF11960.8 GAN01263.1 - 0.066 13.4 0.1 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Na_H_antiport_2 PF13726.6 GAN01263.1 - 0.073 13.2 0.5 0.47 10.6 0.4 2.4 2 0 0 2 2 2 0 Na+-H+ antiporter family Pox_EPC_I2-L1 PF12575.8 GAN01263.1 - 0.096 12.9 1.8 0.46 10.8 0.7 2.7 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF3899 PF13038.6 GAN01263.1 - 0.35 11.4 0.0 0.35 11.4 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) GPI2 PF06432.11 GAN01263.1 - 2.9 7.3 15.0 0.031 13.7 4.2 2.7 4 0 0 4 4 4 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2207 PF09972.9 GAN01263.1 - 8.8 5.0 12.4 2.1 7.0 0.0 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Rieske PF00355.26 GAN01264.1 - 8.1e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GAN01264.1 - 6.7e-11 42.5 0.6 1.9e-10 41.1 0.6 1.8 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region SUKH-4 PF14435.6 GAN01264.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 SUKH-4 immunity protein RPT PF13446.6 GAN01265.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 A repeated domain in UCH-protein Ank_2 PF12796.7 GAN01266.1 - 2.4e-20 72.9 0.1 6.9e-12 45.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN01266.1 - 1.3e-17 62.0 0.8 9.2e-05 22.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GAN01266.1 - 3.4e-16 59.4 0.4 7.2e-10 39.2 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAN01266.1 - 3.4e-11 43.1 5.2 0.0048 17.3 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAN01266.1 - 2.9e-08 33.8 2.7 0.0012 19.1 0.0 4.7 1 1 4 5 5 5 3 Ankyrin repeats (many copies) GrpE PF01025.19 GAN01266.1 - 0.05 13.3 0.2 0.05 13.3 0.2 1.9 2 0 0 2 2 2 0 GrpE Pkinase PF00069.25 GAN01267.1 - 3.3e-65 220.1 0.0 7.2e-65 219.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01267.1 - 1.5e-39 135.9 0.0 2.7e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN01267.1 - 4.6e-05 22.9 0.0 0.00051 19.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 GAN01267.1 - 0.00038 19.9 1.0 0.00094 18.6 1.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN01267.1 - 0.14 12.1 0.7 1.5 8.7 0.3 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family SUIM_assoc PF16619.5 GAN01267.1 - 0.42 10.7 28.7 0.76 9.9 2.4 4.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 GAN01267.1 - 0.81 10.3 4.0 3.1 8.4 2.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_S10 PF00450.22 GAN01268.1 - 6.1e-120 401.4 2.3 6.1e-120 401.4 2.3 1.7 2 0 0 2 2 2 1 Serine carboxypeptidase HD PF01966.22 GAN01268.1 - 5.9e-14 52.3 0.0 2e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 GAN01268.1 - 0.034 13.9 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase GATA PF00320.27 GAN01269.1 - 1.2e-15 56.8 3.6 1.2e-15 56.8 3.6 1.9 2 0 0 2 2 2 1 GATA zinc finger zinc_ribbon_9 PF14369.6 GAN01269.1 - 0.04 14.2 1.0 0.13 12.6 1.0 1.8 1 0 0 1 1 1 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 GAN01269.1 - 0.14 11.7 2.7 0.3 10.6 2.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding RGS12_us1 PF16613.5 GAN01269.1 - 0.66 10.3 0.1 0.66 10.3 0.1 3.2 3 1 0 3 3 3 0 Unstructured region of RGS12 Auto_anti-p27 PF06677.12 GAN01269.1 - 3.1 8.0 5.8 0.25 11.5 0.9 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PSRT PF07636.11 GAN01269.1 - 4.6 7.0 8.7 0.93 9.2 4.0 2.2 2 0 0 2 2 2 0 PSRT Asp PF00026.23 GAN01270.1 - 7.9e-49 166.8 0.1 9.4e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN01270.1 - 3.7e-08 33.8 0.4 5.5e-07 30.0 0.2 2.7 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN01270.1 - 0.0004 21.0 0.0 1.1 10.0 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAN01270.1 - 0.041 14.5 0.0 9.5 6.9 0.0 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.23 GAN01272.1 - 5.2e-52 177.2 32.3 3.9e-35 121.8 3.5 3.6 4 0 0 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN01272.1 - 3e-51 173.6 0.1 4.3e-29 101.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN01272.1 - 8.2e-11 41.8 1.6 0.00024 20.6 0.3 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 GAN01272.1 - 5.5e-07 28.9 0.1 0.0035 16.4 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.6 GAN01272.1 - 1.9e-06 28.4 0.6 0.0024 18.3 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAN01272.1 - 4.8e-06 26.9 4.9 0.066 13.5 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAN01272.1 - 1.1e-05 25.0 0.3 0.18 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAN01272.1 - 1.2e-05 25.2 0.2 1.6 8.4 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 GAN01272.1 - 2.1e-05 25.1 2.0 0.028 14.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 GAN01272.1 - 2.6e-05 23.9 0.7 0.032 13.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain DUF87 PF01935.17 GAN01272.1 - 3.3e-05 24.1 0.8 0.01 16.0 0.0 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_33 PF13671.6 GAN01272.1 - 0.0011 19.1 4.2 0.35 11.0 0.2 3.2 2 1 1 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 GAN01272.1 - 0.0015 18.0 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 GAN01272.1 - 0.0017 18.3 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAN01272.1 - 0.0025 17.9 0.2 0.33 11.1 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 GAN01272.1 - 0.0029 18.2 0.2 5.1 7.7 0.1 3.2 3 0 0 3 3 2 0 AAA domain SUIM_assoc PF16619.5 GAN01272.1 - 0.0036 17.4 4.3 0.0084 16.2 4.3 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 cobW PF02492.19 GAN01272.1 - 0.0037 16.9 1.2 0.087 12.4 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 GAN01272.1 - 0.0038 17.3 0.6 0.44 10.6 0.0 2.7 3 0 0 3 3 2 1 Dynamin family Pox_A32 PF04665.12 GAN01272.1 - 0.0041 16.6 0.3 1.7 8.1 0.1 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein NB-ARC PF00931.22 GAN01272.1 - 0.0046 16.2 0.1 0.6 9.3 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain AAA_21 PF13304.6 GAN01272.1 - 0.0069 16.2 0.4 7.5 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 GAN01272.1 - 0.0075 16.2 6.2 3.4 7.6 0.1 3.4 3 0 0 3 3 3 1 NACHT domain RNA_pol_Rpb2_5 PF04567.17 GAN01272.1 - 0.024 15.2 0.1 9 7.0 0.0 2.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 AAA_30 PF13604.6 GAN01272.1 - 0.026 14.3 0.2 6.3 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 GAN01272.1 - 0.032 14.0 0.3 6.7 6.4 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 GAN01272.1 - 0.035 13.8 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAN01272.1 - 0.037 13.5 0.1 13 5.1 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein ATP_bind_1 PF03029.17 GAN01272.1 - 0.045 13.5 1.2 15 5.3 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAN01272.1 - 0.046 14.1 0.4 11 6.5 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_7 PF12775.7 GAN01272.1 - 0.06 12.9 0.1 15 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 GAN01272.1 - 0.073 12.0 0.2 3.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 GAN01272.1 - 0.096 12.7 0.0 15 5.6 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_15 PF13175.6 GAN01272.1 - 0.097 12.4 0.0 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 GAN01272.1 - 0.15 12.5 1.1 7.5 7.0 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAN01272.1 - 0.16 12.0 0.0 13 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 GAN01272.1 - 0.16 12.2 0.6 32 4.8 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 GAN01272.1 - 0.21 11.6 0.5 45 4.1 0.0 3.3 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 GAN01272.1 - 0.23 11.4 2.0 8.6 6.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Roughex PF06020.11 GAN01272.1 - 0.24 10.4 1.8 0.48 9.5 1.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SbcCD_C PF13558.6 GAN01272.1 - 0.58 10.4 4.1 21 5.4 0.0 3.8 5 0 0 5 5 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 GAN01272.1 - 0.77 9.1 2.4 5.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PE PF00934.20 GAN01272.1 - 3.3 8.1 5.4 1.4 9.3 0.2 2.4 2 0 0 2 2 2 0 PE family EMC3_TMCO1 PF01956.16 GAN01272.1 - 3.3 7.4 12.5 0.49 10.1 1.9 3.3 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Piwi PF02171.17 GAN01273.1 - 4.5e-78 262.5 0.1 2e-76 257.2 0.1 2.1 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 GAN01273.1 - 1.5e-19 71.0 0.0 3.6e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 GAN01273.1 - 2.7e-14 53.1 0.0 5.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 GAN01273.1 - 2.1e-12 47.1 0.1 7e-12 45.5 0.1 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 GAN01273.1 - 1.7e-07 31.4 0.0 6e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute Rax2 PF12768.7 GAN01274.1 - 8.5e-34 116.9 3.4 3.7e-33 114.8 0.1 3.6 3 1 1 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 GAN01274.1 - 7e-08 32.0 1.0 1.3e-07 31.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAN01274.1 - 1.5e-07 31.1 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN01274.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 GAN01274.1 - 0.12 12.7 2.4 2.6 8.5 0.0 4.1 4 0 0 4 4 4 0 Kelch motif RNase_PH PF01138.21 GAN01275.1 - 3.3e-38 131.2 0.0 5.1e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAN01275.1 - 1.1e-08 35.0 0.1 1.8e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.27 GAN01276.1 - 5.3e-46 154.5 2.2 9.9e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GRDP-like PF07173.12 GAN01276.1 - 0.07 13.8 0.4 0.15 12.7 0.4 1.6 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like CBS PF00571.28 GAN01277.1 - 1.8e-24 85.9 3.6 1.5e-09 38.2 0.0 4.7 5 0 0 5 5 5 4 CBS domain ACT PF01842.25 GAN01278.1 - 7.5e-14 51.2 0.2 1.4e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 GAN01278.1 - 5e-09 35.9 0.1 1e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAN01278.1 - 0.061 13.9 0.1 0.15 12.7 0.1 1.6 1 0 0 1 1 1 0 ACT domain LytR_C PF13399.6 GAN01278.1 - 0.095 13.7 0.0 0.35 11.9 0.0 1.9 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator ResIII PF04851.15 GAN01279.1 - 9.7e-19 68.0 0.2 9.7e-19 68.0 0.2 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN01279.1 - 7.7e-13 48.8 0.6 4e-12 46.4 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 GAN01279.1 - 7.6e-06 25.8 0.1 1.9e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 GAN01279.1 - 1.8e-05 24.6 0.0 4.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RbpA PF13397.6 GAN01279.1 - 0.0025 18.4 0.1 0.0063 17.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase-binding protein SNF2_N PF00176.23 GAN01279.1 - 0.023 13.4 0.3 0.057 12.1 0.0 1.7 2 1 0 2 2 2 0 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 GAN01279.1 - 0.028 13.6 0.8 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Glyco_hydro_66 PF13199.6 GAN01279.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 GST_C_3 PF14497.6 GAN01280.1 - 3.3e-20 72.1 0.1 7.7e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN01280.1 - 1.2e-07 31.9 0.0 2.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAN01280.1 - 0.00018 21.8 0.1 0.00043 20.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN01280.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAN01280.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAN01280.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAN01280.1 - 0.02 15.3 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain LIM PF00412.22 GAN01281.1 - 2.2e-24 85.4 22.7 3.7e-12 46.3 6.7 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 GAN01281.1 - 0.7 9.5 16.0 2.3 7.9 0.8 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 GAN01281.1 - 0.75 9.9 0.1 0.75 9.9 0.1 3.9 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain DUF2616 PF11077.8 GAN01281.1 - 3.2 7.4 9.1 4.3 7.0 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) CsbD PF05532.12 GAN01282.1 - 6.4e-16 58.0 18.4 4.7e-11 42.4 6.4 2.0 1 1 1 2 2 2 2 CsbD-like Mito_carr PF00153.27 GAN01283.1 - 6.5e-67 221.5 8.8 7.8e-22 77.0 0.3 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAN01283.1 - 1e-14 54.7 1.5 1e-06 29.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAN01283.1 - 2.9e-09 35.8 4.5 0.00035 19.9 0.5 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 GAN01283.1 - 6.4e-09 35.0 5.7 0.032 14.2 0.3 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GAN01283.1 - 1e-07 31.7 0.6 0.006 16.4 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAN01283.1 - 0.00012 21.5 0.2 0.41 10.2 0.2 2.6 2 0 0 2 2 2 2 EF hand Serine_protease PF18405.1 GAN01283.1 - 0.00013 21.2 4.0 0.19 10.9 0.1 2.7 3 0 0 3 3 3 2 Gammaproteobacterial serine protease SPARC_Ca_bdg PF10591.9 GAN01283.1 - 0.14 12.5 2.1 2 8.8 0.0 2.8 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region PIF1 PF05970.14 GAN01284.1 - 0.0018 17.5 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ATG_C PF09333.11 GAN01286.1 - 7.8e-29 99.9 0.0 2.9e-28 98.1 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 GAN01286.1 - 4.6e-17 62.2 0.2 4.6e-17 62.2 0.2 3.4 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 GAN01286.1 - 8.2e-13 48.4 0.1 5.2e-12 45.7 0.1 2.4 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif zf-CCHC PF00098.23 GAN01286.1 - 7.7e-12 44.7 24.4 0.006 16.6 0.5 4.4 4 0 0 4 4 4 4 Zinc knuckle VPS13_C PF16909.5 GAN01286.1 - 1.1e-05 25.3 0.3 7.1e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal zf-CCHC_4 PF14392.6 GAN01286.1 - 0.01 15.5 16.8 0.85 9.4 0.8 4.6 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_2 PF13696.6 GAN01286.1 - 0.02 14.7 25.0 0.014 15.2 1.7 4.3 4 0 0 4 4 4 0 Zinc knuckle TIP49 PF06068.13 GAN01287.1 - 9.9e-172 570.9 0.3 1.3e-171 570.6 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAN01287.1 - 8.9e-23 80.2 0.1 2.5e-22 78.8 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAN01287.1 - 2.3e-11 44.2 0.1 1.1e-06 29.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAN01287.1 - 6.4e-10 39.0 0.1 8.3e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAN01287.1 - 1.4e-05 25.4 0.0 0.025 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAN01287.1 - 0.0001 22.8 0.0 0.006 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 GAN01287.1 - 0.0022 18.0 0.1 0.09 12.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 GAN01287.1 - 0.0024 17.3 0.1 0.073 12.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAN01287.1 - 0.0031 17.5 0.1 0.33 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAN01287.1 - 0.0037 17.3 0.4 1.4 8.9 0.0 3.5 2 1 2 4 4 4 1 AAA domain Sigma54_activat PF00158.26 GAN01287.1 - 0.0052 16.5 0.1 3 7.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 GAN01287.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 GAN01287.1 - 0.019 15.3 3.9 0.14 12.5 2.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 GAN01287.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAN01287.1 - 0.031 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAN01287.1 - 0.045 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 GAN01287.1 - 0.073 12.3 0.2 0.18 11.1 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GAN01287.1 - 0.079 12.5 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAN01287.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 GAN01287.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 GAN01287.1 - 0.12 12.5 0.0 0.7 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 GAN01287.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Reticulon PF02453.17 GAN01288.1 - 2e-29 102.6 6.4 2.6e-29 102.2 6.4 1.1 1 0 0 1 1 1 1 Reticulon YfzA PF14118.6 GAN01288.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 YfzA-like protein SPC22 PF04573.12 GAN01289.1 - 1.4e-48 164.6 2.7 1.7e-48 164.3 2.7 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF5126 PF17166.4 GAN01289.1 - 0.012 15.5 0.4 0.023 14.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) Pkinase PF00069.25 GAN01290.1 - 5e-72 242.4 0.0 6.2e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01290.1 - 5.4e-39 134.0 0.0 7.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAN01290.1 - 0.0059 16.3 0.1 0.51 9.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Alg6_Alg8 PF03155.15 GAN01291.1 - 1.2e-157 525.8 31.4 1.9e-156 521.8 31.4 1.9 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Sugar_tr PF00083.24 GAN01292.1 - 1.2e-52 179.3 2.3 1.7e-52 178.8 1.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN01292.1 - 4.3e-15 55.5 9.4 5e-15 55.3 9.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAN01292.1 - 0.15 10.5 3.3 0.2 10.0 3.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAN01293.1 - 9.9e-58 196.1 8.0 1.5e-53 182.3 5.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN01293.1 - 6.1e-17 61.6 1.6 6.1e-17 61.6 1.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Rap_GAP PF02145.15 GAN01295.1 - 1.4e-53 181.2 0.6 6e-53 179.2 0.0 2.4 2 1 0 2 2 2 1 Rap/ran-GAP DUF4296 PF14129.6 GAN01295.1 - 0.39 11.3 4.0 0.21 12.2 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Integrase_H2C2 PF17921.1 GAN01296.1 - 1.1e-07 31.9 1.3 1.9e-07 31.1 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GAN01296.1 - 0.093 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Imm5 PF14423.6 GAN01296.1 - 0.16 12.2 1.8 19 5.4 0.0 2.4 2 0 0 2 2 2 0 Immunity protein Imm5 DUF4148 PF13663.6 GAN01296.1 - 0.19 11.9 11.2 5.4 7.3 0.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) B56 PF01603.20 GAN01297.1 - 1.6e-189 630.2 7.4 1.9e-189 629.9 7.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) MSP1_C PF07462.11 GAN01297.1 - 1.6 7.3 11.0 3.1 6.4 11.0 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SWI-SNF_Ssr4 PF08549.10 GAN01297.1 - 9.5 4.7 13.1 14 4.1 13.1 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3835 PF12927.7 GAN01298.1 - 3e-13 50.4 9.6 4e-12 46.8 5.3 7.0 5 2 2 7 7 7 3 Domain of unknown function (DUF3835) Prefoldin PF02996.17 GAN01299.1 - 1.3e-19 70.3 0.3 1.7e-19 69.9 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 GAN01299.1 - 1.1e-11 44.6 0.3 1.7e-11 44.1 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit Glyco_hydro_8 PF01270.17 GAN01299.1 - 0.0037 16.1 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 DUF4164 PF13747.6 GAN01299.1 - 0.09 13.1 1.8 1.9 8.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) L31 PF09784.9 GAN01299.1 - 0.1 13.0 0.3 0.62 10.5 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 FliD_N PF02465.18 GAN01299.1 - 0.28 11.9 5.5 0.55 11.0 2.4 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SRF-TF PF00319.18 GAN01300.1 - 3.9e-21 74.3 0.1 5.8e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Pkinase PF00069.25 GAN01301.1 - 1.6e-65 221.1 1.0 4.4e-63 213.1 1.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01301.1 - 2.6e-37 128.5 0.2 3.4e-35 121.6 0.2 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAN01301.1 - 8.4e-07 28.5 0.7 1.6e-06 27.6 0.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAN01301.1 - 2.7e-06 27.1 0.7 5.5e-06 26.1 0.7 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 GAN01301.1 - 1.4e-05 24.5 0.0 3.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAN01301.1 - 3.1e-05 24.0 6.2 0.0011 18.9 0.1 3.4 2 2 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN01301.1 - 0.00078 18.5 0.2 0.0016 17.5 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 GAN01301.1 - 0.02 14.4 3.4 0.099 12.1 3.4 2.0 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 GAN01301.1 - 0.059 13.0 0.4 0.18 11.4 0.3 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 GAN01301.1 - 0.084 11.6 0.4 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase NOA36 PF06524.12 GAN01301.1 - 1.1 8.6 6.1 1.7 7.9 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1771 PF08590.10 GAN01302.1 - 2.2e-18 66.4 5.5 2.2e-18 66.4 5.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 GAN01302.1 - 5.4e-12 45.9 0.1 1.3e-11 44.6 0.1 1.7 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 GAN01302.1 - 9.3e-08 31.9 1.4 9.3e-08 31.9 1.4 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 GAN01302.1 - 2.4e-07 30.4 5.6 8.5e-06 25.4 0.7 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 GAN01302.1 - 2e-05 25.3 3.8 0.0036 18.0 0.2 2.9 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 GAN01302.1 - 6.4e-05 22.7 8.5 0.00029 20.7 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GAN01302.1 - 0.0032 17.9 9.3 0.12 12.9 0.5 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HBS1_N PF08938.10 GAN01302.1 - 0.014 15.7 0.3 0.014 15.7 0.3 3.5 3 0 0 3 3 3 0 HBS1 N-terminus CUE PF02845.16 GAN01302.1 - 0.051 13.3 1.5 0.14 11.9 0.4 2.1 2 0 0 2 2 2 0 CUE domain zf-CCCH_3 PF15663.5 GAN01302.1 - 0.077 13.2 7.0 1.6e+02 2.6 1.6 2.5 1 1 0 1 1 1 0 Zinc-finger containing family Alpha_E3_glycop PF01563.16 GAN01303.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein DPBB_1 PF03330.18 GAN01304.1 - 1.3e-05 25.4 0.0 1.8e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN01304.1 - 0.021 14.7 0.2 0.027 14.3 0.2 1.3 1 0 0 1 1 1 0 Barwin family PAS PF00989.25 GAN01305.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold Chromo PF00385.24 GAN01306.1 - 1.5e-16 60.0 1.3 1.5e-16 60.0 1.3 2.7 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 GAN01306.1 - 1.2e-10 41.3 0.5 7.5e-08 32.4 0.1 2.6 2 0 0 2 2 2 2 Chromo shadow domain DUF1087 PF06465.13 GAN01306.1 - 0.026 14.6 0.4 0.026 14.6 0.4 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) GREB1 PF15782.5 GAN01306.1 - 0.12 9.5 4.9 0.14 9.3 4.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Med3 PF11593.8 GAN01306.1 - 2.1 7.5 9.6 3 6.9 9.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AT_hook PF02178.19 GAN01306.1 - 8.7 6.6 13.1 0.4 10.7 7.0 2.2 2 0 0 2 2 2 0 AT hook motif adh_short_C2 PF13561.6 GAN01307.1 - 5.1e-50 170.2 0.9 6.4e-50 169.9 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN01307.1 - 7.6e-49 165.8 0.6 1.1e-48 165.3 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAN01307.1 - 6.8e-10 39.2 0.1 1.7e-09 37.8 0.1 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 GAN01307.1 - 0.00043 19.8 0.1 0.00098 18.7 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 GAN01307.1 - 0.068 12.9 0.1 3 7.5 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain LemA PF04011.12 GAN01307.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 LemA family F420_oxidored PF03807.17 GAN01307.1 - 0.093 13.3 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 GAN01307.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) SH3_1 PF00018.28 GAN01308.1 - 7.3e-17 60.7 0.0 1.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN01308.1 - 4.3e-13 48.9 0.0 6.6e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Peroxin-13_N PF04088.13 GAN01308.1 - 7.3e-13 49.0 4.6 7.4e-12 45.8 4.6 2.0 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 GAN01308.1 - 1.6e-11 43.7 0.0 2.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HisG PF01634.18 GAN01310.1 - 7e-53 178.9 0.5 8.5e-53 178.6 0.5 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase NMT1 PF09084.11 GAN01310.1 - 0.047 13.6 0.1 0.091 12.7 0.1 1.5 1 1 0 1 1 1 0 NMT1/THI5 like Asp PF00026.23 GAN01311.1 - 1.3e-17 64.2 0.0 1.4e-08 34.6 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 GAN01311.1 - 0.035 14.7 0.1 5.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 GAN01311.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase PF00069.25 GAN01312.1 - 1.4e-45 155.7 0.0 2.2e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01312.1 - 2.2e-26 92.7 0.0 2.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAN01312.1 - 0.0022 17.1 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 GAN01312.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN01312.1 - 0.0039 17.1 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 GAN01313.1 - 3e-60 204.0 51.6 4.5e-60 203.4 51.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_16 PF00722.21 GAN01314.1 - 5.2e-07 29.3 0.0 9.5e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2183 PF09949.9 GAN01316.1 - 1.5e-32 111.8 0.5 5.8e-32 110.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) ATP-grasp_2 PF08442.10 GAN01316.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Senescence_reg PF04520.13 GAN01316.1 - 4.8 8.0 9.4 1.5 9.7 5.8 2.0 2 0 0 2 2 2 0 Senescence regulator Sox_N PF12444.8 GAN01316.1 - 7 7.9 8.3 4.1 8.6 4.4 2.6 2 0 0 2 2 2 0 Sox developmental protein N terminal Kinesin PF00225.23 GAN01317.1 - 1.9e-76 257.2 1.7 1.9e-76 257.2 1.7 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN01317.1 - 4.7e-56 188.9 0.2 1.7e-55 187.0 0.2 2.0 1 0 0 1 1 1 1 Microtubule binding Tmemb_cc2 PF10267.9 GAN01317.1 - 0.00094 18.4 21.6 0.00094 18.4 21.6 2.7 1 1 1 3 3 3 1 Predicted transmembrane and coiled-coil 2 protein DUF4404 PF14357.6 GAN01317.1 - 0.63 10.7 19.6 4.8 7.9 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF745 PF05335.13 GAN01317.1 - 0.76 9.5 20.9 0.034 13.9 8.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Filament PF00038.21 GAN01317.1 - 1.1 8.7 31.8 0.022 14.3 12.0 3.0 1 1 2 3 3 3 0 Intermediate filament protein ATG16 PF08614.11 GAN01317.1 - 1.7 8.9 43.7 0.22 11.7 16.1 3.5 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 GAN01317.1 - 2.1 6.8 6.6 1.3 7.5 4.6 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF948 PF06103.11 GAN01317.1 - 2.9 8.2 9.6 0.21 11.9 1.4 3.1 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 GAN01317.1 - 7 5.4 40.5 11 4.8 17.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 GAN01317.1 - 8.2 6.4 39.4 3.2 7.8 19.3 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 tRNA-synt_2d PF01409.20 GAN01318.1 - 5e-89 298.0 0.1 6.9e-89 297.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GAN01318.1 - 1.6e-20 73.1 0.3 4.2e-20 71.8 0.3 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 GAN01318.1 - 1.2e-06 28.1 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 GAN01318.1 - 7.2e-05 22.0 0.7 0.0015 17.7 0.1 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 GAN01318.1 - 0.00077 19.4 1.1 0.0021 18.0 1.1 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 PheRS_DBD1 PF18552.1 GAN01318.1 - 0.018 14.8 0.0 0.053 13.3 0.0 1.9 2 0 0 2 2 2 0 PheRS DNA binding domain 1 OrsD PF12013.8 GAN01319.1 - 0.012 16.0 1.3 0.019 15.4 1.3 1.3 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D PMEI PF04043.15 GAN01319.1 - 0.19 12.1 3.1 0.91 9.9 2.1 2.3 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Tmemb_cc2 PF10267.9 GAN01319.1 - 0.22 10.7 3.4 0.27 10.3 3.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SR-25 PF10500.9 GAN01319.1 - 1.2 8.7 7.8 1.6 8.3 7.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Endotoxin_C PF03944.14 GAN01319.1 - 7.3 6.9 7.0 4.6 7.6 3.9 2.1 2 1 1 3 3 3 0 delta endotoxin DIOX_N PF14226.6 GAN01320.1 - 1e-27 97.2 0.5 2.1e-27 96.2 0.5 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAN01320.1 - 7.8e-20 71.3 0.0 1.4e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mitoc_mL59 PF18126.1 GAN01321.1 - 1.6e-10 41.3 5.3 2.1e-09 37.8 5.3 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 CR6_interact PF10147.9 GAN01321.1 - 0.0055 16.5 5.2 0.0081 15.9 5.2 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Spem1 PF15670.5 GAN01321.1 - 0.028 14.0 0.4 0.037 13.6 0.4 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF865 PF05906.11 GAN01321.1 - 0.23 11.3 0.8 0.42 10.5 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Ribosomal_L32e PF01655.18 GAN01322.1 - 3.8e-49 165.6 0.5 4.6e-49 165.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 FHA PF00498.26 GAN01323.1 - 2.8e-17 62.8 1.3 4.7e-17 62.1 0.1 2.0 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 GAN01323.1 - 2.8e-10 39.7 11.8 5.7e-10 38.8 11.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAN01323.1 - 1.1e-07 32.0 10.5 1.8e-07 31.4 10.5 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 GAN01323.1 - 0.0008 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 GAN01323.1 - 0.00087 19.1 12.0 0.0015 18.3 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN01323.1 - 0.0095 15.8 11.0 0.017 15.0 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN01323.1 - 0.022 15.0 10.6 0.073 13.4 10.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAN01323.1 - 0.028 14.4 1.6 0.059 13.4 1.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAN01323.1 - 0.05 13.6 9.9 0.096 12.7 9.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 GAN01323.1 - 0.29 11.0 7.1 0.56 10.1 7.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 GAN01323.1 - 0.87 9.7 11.8 1.7 8.7 11.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zinc_ribbon_10 PF10058.9 GAN01325.1 - 1.4e-18 66.3 0.6 2.7e-18 65.4 0.6 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein TFIIA PF03153.13 GAN01325.1 - 0.0041 17.2 23.0 0.0063 16.6 23.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF778 PF05608.12 GAN01325.1 - 0.0099 16.3 0.1 0.03 14.7 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF778) SMN PF06003.12 GAN01325.1 - 0.011 15.0 0.6 0.011 15.0 0.6 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF3810 PF12725.7 GAN01325.1 - 0.014 14.7 0.9 0.031 13.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Comm PF15957.5 GAN01325.1 - 0.014 15.7 0.3 0.014 15.7 0.3 2.5 3 0 0 3 3 3 0 Commissureless DUF2663 PF10864.8 GAN01325.1 - 0.06 13.7 5.4 0.058 13.8 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2417 PF10329.9 GAN01325.1 - 0.091 12.2 0.9 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) tRNA_anti-like PF12869.7 GAN01325.1 - 0.13 11.9 3.1 0.26 10.9 0.4 2.4 2 0 0 2 2 2 0 tRNA_anti-like O-antigen_lig PF13425.6 GAN01325.1 - 0.37 9.5 7.6 0.039 12.7 0.4 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein MtrG PF04210.13 GAN01325.1 - 0.45 10.4 0.0 0.45 10.4 0.0 2.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G zf-U1 PF06220.12 GAN01326.1 - 5.8e-22 77.2 3.4 8e-22 76.7 3.4 1.2 1 0 0 1 1 1 1 U1 zinc finger LPD39 PF18858.1 GAN01326.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 2OG-FeII_Oxy_2 PF13532.6 GAN01327.1 - 6.1e-15 55.9 0.0 7.2e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.23 GAN01328.1 - 2.4e-59 200.8 0.0 2.4e-59 200.8 0.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN01328.1 - 5.9e-17 62.0 0.0 5.9e-17 62.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 GAN01328.1 - 3.2e-15 55.8 3.7 5.1e-10 39.1 0.4 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 GAN01328.1 - 0.012 15.8 0.0 0.055 13.7 0.0 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain PQ-loop PF04193.14 GAN01330.1 - 1.1e-25 89.2 12.3 2.1e-13 49.8 2.0 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4293 PF14126.6 GAN01330.1 - 7.7e-05 23.0 3.2 0.00018 21.8 2.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4293) MadM PF03818.13 GAN01331.1 - 0.08 12.8 0.7 4.7 7.2 0.0 2.8 2 1 1 3 3 3 0 Malonate/sodium symporter MadM subunit Tam41_Mmp37 PF09139.11 GAN01334.1 - 3.6e-120 401.3 0.1 3.6e-120 401.3 0.1 1.4 2 0 0 2 2 2 1 Phosphatidate cytidylyltransferase, mitochondrial DUF5384 PF17358.2 GAN01334.1 - 0.039 14.0 0.1 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5384) Med3 PF11593.8 GAN01335.1 - 3.8 6.6 13.4 4.2 6.5 13.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pil1 PF13805.6 GAN01336.1 - 4.9e-27 95.1 8.7 1e-26 94.0 8.7 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 TraI_2_C PF07515.11 GAN01336.1 - 0.15 12.0 3.2 7.9 6.4 3.2 2.7 1 1 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term DUF4407 PF14362.6 GAN01336.1 - 0.28 10.5 12.5 0.011 15.1 5.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATP_bind_1 PF03029.17 GAN01337.1 - 2e-82 276.6 0.0 2.4e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 GAN01337.1 - 4.5e-05 23.3 0.0 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 GAN01337.1 - 0.0076 16.4 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 GAN01337.1 - 0.0096 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAN01337.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 GAN01337.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 GAN01337.1 - 0.021 14.9 0.0 0.027 14.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 GAN01337.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 GAN01337.1 - 0.045 13.7 0.0 0.49 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 GAN01337.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 GAN01337.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 GAN01337.1 - 0.17 12.3 0.2 0.61 10.5 0.2 2.0 1 0 0 1 1 1 0 AAA domain Prok-RING_4 PF14447.6 GAN01338.1 - 0.072 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prim-Pol PF09250.11 GAN01338.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Sin_N PF04801.13 GAN01339.1 - 7.4e-48 163.8 4.5 1e-47 163.3 4.5 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region RNA_pol_Rpb8 PF03870.15 GAN01339.1 - 0.035 14.3 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb8 ANAPC15 PF15243.6 GAN01340.1 - 0.11 12.9 18.8 1.4 9.3 13.4 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF572 PF04502.13 GAN01340.1 - 0.32 10.6 22.0 0.5 9.9 18.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) GREB1 PF15782.5 GAN01340.1 - 0.65 7.0 17.3 0.89 6.6 17.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BTV_NS2 PF04514.12 GAN01340.1 - 2.1 7.1 7.8 3.3 6.4 7.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SOBP PF15279.6 GAN01340.1 - 2.4 8.7 33.6 2.4 8.7 1.9 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein RRN3 PF05327.11 GAN01340.1 - 3.4 6.1 10.4 5.2 5.5 10.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TipE PF16972.5 GAN01340.1 - 3.6 6.7 6.8 5.3 6.1 6.8 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE LAP1C PF05609.12 GAN01340.1 - 6.8 5.7 19.9 0.49 9.4 14.1 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Gly_transf_sug PF04488.15 GAN01342.1 - 1.1e-05 26.0 0.0 2.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RRM_1 PF00076.22 GAN01343.1 - 2.3e-26 91.4 0.2 4.6e-13 48.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAN01343.1 - 3.9e-09 36.2 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN01343.1 - 0.00018 21.3 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GAN01343.1 - 0.0076 16.3 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.11 GAN01343.1 - 0.043 13.8 0.1 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 RNA binding motif Pkinase PF00069.25 GAN01344.1 - 1.6e-09 37.5 0.0 5.4e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01344.1 - 1.6e-05 24.3 0.0 9e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAN01344.1 - 0.0058 16.0 0.1 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PUF PF00806.19 GAN01344.1 - 0.019 14.6 0.1 0.049 13.3 0.1 1.7 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF5087 PF17006.5 GAN01344.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5087) YMF19 PF02326.15 GAN01345.1 - 0.42 11.4 2.5 0.86 10.4 0.0 2.6 3 0 0 3 3 3 0 Plant ATP synthase F0 Peptidase_C12 PF01088.21 GAN01346.1 - 6.3e-50 169.9 0.2 6.3e-50 169.9 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF872 PF05915.12 GAN01347.1 - 4.4e-12 46.2 0.1 5.3e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Oleosin PF01277.17 GAN01347.1 - 0.3 10.9 2.2 0.38 10.5 2.2 1.1 1 0 0 1 1 1 0 Oleosin EMP24_GP25L PF01105.24 GAN01348.1 - 1.1e-42 146.1 2.5 1.3e-42 145.8 2.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 GAN01348.1 - 0.047 13.9 0.1 0.088 13.0 0.1 1.4 1 1 0 1 1 1 0 SdrD B-like domain IL1 PF00340.19 GAN01348.1 - 0.067 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Interleukin-1 / 18 Y_Y_Y PF07495.13 GAN01348.1 - 0.096 12.7 0.7 6.4 6.8 0.0 2.8 3 0 0 3 3 3 0 Y_Y_Y domain CarboxypepD_reg PF13620.6 GAN01348.1 - 0.18 12.1 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Tubulin PF00091.25 GAN01349.1 - 2.1e-65 220.6 0.0 4.9e-65 219.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain CENP-I PF07778.11 GAN01349.1 - 4e-46 157.8 12.5 4e-25 88.5 0.5 2.2 1 1 1 2 2 2 2 Mis6 Tubulin_C PF03953.17 GAN01349.1 - 1.3e-40 138.4 0.0 3e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 GAN01349.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Hydrolase_4 PF12146.8 GAN01349.1 - 0.14 11.4 0.1 0.78 9.0 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Vps5 PF09325.10 GAN01350.1 - 2.4e-58 197.5 13.9 4e-49 167.3 7.6 2.4 1 1 1 2 2 2 2 Vps5 C terminal like PX PF00787.24 GAN01350.1 - 4.1e-24 84.8 0.3 3.2e-22 78.6 0.0 2.7 2 0 0 2 2 2 1 PX domain TruB_N PF01509.18 GAN01350.1 - 8.5 6.7 7.4 7.2 7.0 0.8 2.8 2 1 1 3 3 3 0 TruB family pseudouridylate synthase (N terminal domain) Hep_59 PF07052.11 GAN01351.1 - 8.1e-33 113.4 1.2 8.1e-33 113.4 1.2 2.8 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF5093 PF17011.5 GAN01351.1 - 4.8 7.5 7.6 2.8 8.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) Methyltransf_32 PF13679.6 GAN01351.1 - 4.9 7.1 5.4 1.2 9.2 1.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain DUF2387 PF09526.10 GAN01352.1 - 0.16 12.1 1.8 2.2 8.5 0.1 2.5 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) DUF3336 PF11815.8 GAN01353.1 - 4.6e-40 136.5 2.7 5.9e-40 136.2 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAN01353.1 - 5.1e-11 43.1 1.1 3.6e-10 40.3 0.2 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase DUF2624 PF11116.8 GAN01354.1 - 0.077 13.9 0.1 0.16 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) F-box-like PF12937.7 GAN01355.1 - 0.0017 18.2 1.1 0.0047 16.8 1.1 1.8 1 0 0 1 1 1 1 F-box-like DUSP PF06337.12 GAN01355.1 - 0.0029 18.2 4.5 0.055 14.1 0.0 2.7 3 0 0 3 3 3 1 DUSP domain F-box PF00646.33 GAN01355.1 - 0.011 15.6 0.1 0.031 14.2 0.1 1.8 1 0 0 1 1 1 0 F-box domain zf-UBP PF02148.19 GAN01355.1 - 0.013 15.8 8.7 0.013 15.8 8.7 2.7 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein Elongin_A PF06881.11 GAN01355.1 - 0.019 15.5 5.7 0.021 15.3 2.9 2.3 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3020 PF11223.8 GAN01356.1 - 1.6e-21 76.6 14.8 1.6e-21 76.6 14.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) Chitin_synth_2 PF03142.15 GAN01358.1 - 8e-227 754.0 2.4 1.2e-226 753.4 2.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAN01358.1 - 3.5e-130 435.4 0.1 4.4e-130 435.0 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 GAN01358.1 - 2.6e-20 72.3 0.7 2e-14 53.5 0.1 3.8 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 GAN01358.1 - 2.4e-13 50.5 0.1 6.5e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN01358.1 - 2.6e-11 43.8 1.8 2.6e-11 43.8 1.8 2.3 2 1 0 2 2 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAN01358.1 - 0.0014 18.5 0.0 0.4 10.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 RNA_helicase PF00910.22 GAN01358.1 - 0.018 15.4 0.1 0.12 12.8 0.0 2.5 2 0 0 2 2 1 0 RNA helicase DUF2443 PF10398.9 GAN01358.1 - 0.037 14.1 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Glyco_transf_21 PF13506.6 GAN01358.1 - 0.041 13.3 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 AAA_16 PF13191.6 GAN01358.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAN01358.1 - 0.077 13.3 0.2 0.32 11.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 GAN01358.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 GAN01358.1 - 0.16 12.3 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain G_glu_transpept PF01019.21 GAN01359.1 - 5.2e-172 573.2 0.0 8.3e-172 572.5 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DNA_pol_B PF00136.21 GAN01359.1 - 3.5e-102 342.5 0.5 6.4e-102 341.6 0.5 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAN01359.1 - 1.3e-37 129.7 0.0 2.9e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 GAN01359.1 - 4.3e-18 65.7 3.7 3.2e-17 62.9 3.7 2.3 1 1 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 GAN01359.1 - 0.01 14.7 0.0 0.026 13.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral SLATT_6 PF18169.1 GAN01359.1 - 0.08 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 zf-ribbon_3 PF13248.6 GAN01359.1 - 0.093 12.2 0.7 0.22 11.0 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-RanBP PF00641.18 GAN01359.1 - 2.6 7.5 4.3 6.1 6.3 4.3 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others NUDIX PF00293.28 GAN01360.1 - 3.4e-10 40.1 0.0 5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 GAN01360.1 - 0.0057 16.2 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4916) RSF PF14876.6 GAN01360.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator MRP PF09387.10 GAN01360.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Nop PF01798.18 GAN01361.1 - 1.6e-90 302.6 0.4 4.2e-90 301.2 0.2 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAN01361.1 - 1.4e-22 79.9 1.4 1.4e-22 79.9 1.4 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 GAN01361.1 - 0.03 14.4 28.9 0.05 13.7 28.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cdh1_DBD_1 PF18196.1 GAN01361.1 - 0.053 13.8 14.1 0.15 12.4 14.1 1.7 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 AP3D1 PF06375.11 GAN01361.1 - 0.16 12.2 16.8 0.28 11.4 16.8 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Med19 PF10278.9 GAN01361.1 - 0.68 9.8 20.0 1.6 8.7 20.0 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RP-C_C PF11800.8 GAN01361.1 - 4.3 7.4 6.8 25 4.9 5.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region RNA_pol_Rpc4 PF05132.14 GAN01361.1 - 9 6.7 12.2 17 5.8 12.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.5 GAN01361.1 - 9.1 6.1 19.5 18 5.1 19.5 1.5 1 0 0 1 1 1 0 Coilin N-terminus Ribosomal_L11 PF00298.19 GAN01362.1 - 2.2e-16 60.1 0.1 3.7e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAN01362.1 - 2e-10 40.3 0.3 4.4e-10 39.2 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain tRNA-synt_2b PF00587.25 GAN01364.1 - 7.1e-22 78.2 0.1 7.9e-21 74.8 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAN01364.1 - 1.9e-12 47.4 4.2 3.8e-12 46.4 4.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain zf-C4H2 PF10146.9 GAN01364.1 - 0.02 15.2 0.9 0.032 14.5 0.9 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2203 PF09969.9 GAN01364.1 - 0.064 14.0 4.9 1.7 9.4 1.4 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) CCD48 PF15799.5 GAN01364.1 - 0.1 10.9 0.7 0.14 10.4 0.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 AAA_23 PF13476.6 GAN01364.1 - 0.18 12.3 1.4 0.29 11.6 1.4 1.3 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 GAN01364.1 - 0.51 8.9 2.1 0.72 8.4 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 GAN01364.1 - 1.1 9.7 4.7 4.5 7.8 0.6 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) EamA PF00892.20 GAN01365.1 - 3.2e-17 63.0 39.2 9.9e-09 35.5 16.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Leader_Trp PF08255.11 GAN01365.1 - 0.14 12.1 0.1 0.49 10.5 0.1 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide LysM PF01476.20 GAN01366.1 - 6.9e-10 38.8 0.2 1.2e-09 38.0 0.2 1.4 1 0 0 1 1 1 1 LysM domain DUF2340 PF10209.9 GAN01367.1 - 9.1e-50 168.1 0.5 1e-49 167.9 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 GAN01367.1 - 0.037 14.3 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain SSP160 PF06933.11 GAN01368.1 - 0.14 10.3 15.2 0.16 10.2 15.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.11 GAN01368.1 - 2.1 8.4 22.5 2.5 8.1 22.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NDT80_PhoG PF05224.12 GAN01369.1 - 1.3e-36 126.6 0.0 1.3e-36 126.6 0.0 3.3 3 1 0 3 3 3 1 NDT80 / PhoG like DNA-binding family F-box-like PF12937.7 GAN01370.1 - 0.00082 19.2 2.3 0.0015 18.4 0.4 2.4 2 0 0 2 2 2 1 F-box-like zf-C2H2 PF00096.26 GAN01371.1 - 0.0014 18.9 1.1 0.0031 17.9 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN01371.1 - 0.014 16.2 0.8 0.038 14.8 0.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Cullin PF00888.22 GAN01374.1 - 8.1e-196 652.3 3.2 8.1e-196 652.3 3.2 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 GAN01374.1 - 3.5e-26 91.0 4.2 1.1e-25 89.4 4.2 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 GAN01374.1 - 0.00039 20.8 0.3 0.0026 18.2 0.0 2.5 2 0 0 2 2 2 1 Phage tail assembly chaperone protein, TAC TFCD_C PF12612.8 GAN01374.1 - 0.024 14.5 0.2 10 5.9 0.0 3.1 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal DUF3658 PF12395.8 GAN01374.1 - 0.13 12.2 1.4 0.29 11.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function MukF_M PF17192.4 GAN01374.1 - 1.6 8.5 4.4 3.3 7.4 0.1 3.1 4 0 0 4 4 4 0 MukF middle domain Ank_4 PF13637.6 GAN01375.1 - 5.3e-14 52.4 0.3 1.9e-08 34.7 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN01375.1 - 8.1e-13 48.8 0.2 1.2e-12 48.2 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN01375.1 - 1.5e-10 41.1 0.3 6.1e-06 26.4 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN01375.1 - 4.4e-10 38.9 0.8 0.0069 16.8 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAN01375.1 - 6.1e-10 39.1 2.0 0.0002 21.7 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Peptidase_M27 PF01742.17 GAN01375.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease DUF3245 PF11595.8 GAN01376.1 - 0.18 12.3 0.5 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF900 PF05990.12 GAN01377.1 - 2.4e-06 27.2 0.0 1.7e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 GAN01377.1 - 0.041 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase OCC1 PF15506.6 GAN01377.1 - 0.061 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 OCC1 family Arrestin_C PF02752.22 GAN01378.1 - 8.2e-19 68.4 0.1 6.9e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN01378.1 - 6.6e-15 55.4 0.0 1.4e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN01378.1 - 0.00063 19.5 0.0 0.0022 17.8 0.0 1.9 1 1 0 1 1 1 1 Arrestin_N terminal like MIF4G PF02854.19 GAN01379.1 - 1.8e-44 151.9 2.4 3.6e-44 150.9 2.4 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 GAN01379.1 - 7.1e-14 51.7 0.3 2e-13 50.3 0.3 1.8 1 0 0 1 1 1 1 MA3 domain eIF_4G1 PF12152.8 GAN01379.1 - 4.9e-07 29.8 0.1 2.5e-06 27.5 0.1 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MMR_HSR1_Xtn PF16897.5 GAN01380.1 - 4.5e-42 142.4 4.2 8.7e-42 141.5 4.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GAN01380.1 - 3.2e-21 75.1 0.1 5.6e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GAN01380.1 - 7.5e-20 71.1 0.0 1.7e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN01380.1 - 6.6e-12 45.2 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAN01380.1 - 0.0018 18.4 0.3 0.28 11.2 0.0 2.5 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 GAN01380.1 - 0.0096 15.8 0.6 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DinI PF06183.13 GAN01380.1 - 0.014 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 DinI-like family Arf PF00025.21 GAN01380.1 - 0.018 14.5 0.0 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 GAN01380.1 - 0.032 13.2 0.1 0.064 12.2 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 GAN01380.1 - 0.032 13.7 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 GAN01380.1 - 0.036 14.3 0.2 0.077 13.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 GAN01380.1 - 0.064 13.5 0.1 0.26 11.5 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ebp2 PF05890.12 GAN01381.1 - 1.8e-40 139.2 25.6 5.4e-39 134.4 25.6 2.1 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF3881 PF12997.7 GAN01381.1 - 0.077 12.2 3.8 0.11 11.7 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) RAB3GAP2_N PF14655.6 GAN01382.1 - 2e-108 363.3 0.0 2.6e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus FAM104 PF15434.6 GAN01382.1 - 1.3 9.6 4.0 5.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Family 104 TPR_14 PF13428.6 GAN01383.1 - 0.00079 20.1 0.3 5.6 8.1 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN01383.1 - 0.0071 16.7 0.0 0.75 10.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN01383.1 - 0.066 13.4 0.5 1.1 9.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Gaa1 PF04114.14 GAN01385.1 - 4.2e-117 392.2 8.8 5.2e-117 391.9 8.8 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Methyltransf_25 PF13649.6 GAN01386.1 - 1.9e-13 50.9 0.0 3.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN01386.1 - 7.4e-11 42.2 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN01386.1 - 7.1e-10 39.4 0.0 1.4e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN01386.1 - 1.3e-07 31.5 0.0 3.3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN01386.1 - 2.7e-06 27.0 0.3 2.6e-05 23.8 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase Ubie_methyltran PF01209.18 GAN01386.1 - 3.1e-06 26.7 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN01386.1 - 1.7e-05 25.5 0.0 3.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GAN01386.1 - 0.00078 18.1 0.0 0.0013 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 GAN01386.1 - 0.0092 16.1 0.0 0.049 13.8 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.20 GAN01386.1 - 0.07 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAN01386.1 - 0.072 12.6 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Dus PF01207.17 GAN01387.1 - 1.4e-72 244.4 0.0 1.8e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 GAN01387.1 - 0.0048 15.9 0.0 0.0073 15.3 0.0 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAN01387.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 GAN01387.1 - 0.022 14.0 0.0 0.047 12.9 0.0 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase GST_N_3 PF13417.6 GAN01388.1 - 4.1e-13 49.5 0.0 1.3e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAN01388.1 - 4.4e-09 36.6 0.0 1.3e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAN01388.1 - 4.7e-09 36.3 0.5 2.7e-08 33.9 0.1 2.3 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAN01388.1 - 2.1e-06 28.0 0.0 4.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAN01388.1 - 8.4e-06 25.9 1.9 8.7e-05 22.7 0.3 3.0 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN01388.1 - 0.0059 16.6 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAN01388.1 - 0.073 13.3 0.0 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin GST_C_4 PF14834.6 GAN01388.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAN01388.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_S7 PF00177.21 GAN01389.1 - 3.3e-37 127.4 0.9 4.1e-37 127.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-C3HC PF07967.13 GAN01390.1 - 4.1e-17 62.4 4.5 5.6e-15 55.5 0.1 3.0 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 GAN01390.1 - 1.5e-11 44.3 7.2 4.4e-08 33.2 0.1 3.2 3 0 0 3 3 3 2 Rsm1-like baeRF_family5 PF18846.1 GAN01390.1 - 0.072 13.3 0.2 0.072 13.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 VRR_NUC PF08774.11 GAN01392.1 - 8.1e-24 83.8 0.2 2.9e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain Rhomboid PF01694.22 GAN01393.1 - 6.5e-22 78.2 13.8 6.8e-22 78.1 11.5 2.1 2 0 0 2 2 2 1 Rhomboid family CrgA PF06781.12 GAN01393.1 - 0.058 13.5 0.9 1.9 8.6 0.1 3.0 3 0 0 3 3 3 0 Cell division protein CrgA Orf78 PF06024.12 GAN01393.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.1 4 0 0 4 4 4 0 Orf78 (ac78) VKOR PF07884.14 GAN01393.1 - 1.4 9.1 8.5 0.48 10.6 3.7 2.5 2 1 1 3 3 3 0 Vitamin K epoxide reductase family DUF2975 PF11188.8 GAN01393.1 - 7.6 6.4 6.7 62 3.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF4203 PF13886.6 GAN01393.1 - 8.4 6.0 17.2 5.8 6.5 9.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) Tyr-DNA_phospho PF06087.12 GAN01395.1 - 1.3e-62 212.1 0.0 1.7e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 GAN01395.1 - 0.00011 22.1 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.20 GAN01395.1 - 0.0067 16.3 4.4 0.19 11.7 1.0 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif Perilipin PF03036.16 GAN01396.1 - 3.9e-10 39.3 25.8 4e-05 22.8 1.2 2.6 1 1 1 2 2 2 2 Perilipin family OrgA_MxiK PF09482.10 GAN01396.1 - 0.089 12.7 1.2 0.23 11.3 0.9 1.9 1 1 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Apolipoprotein PF01442.18 GAN01396.1 - 0.094 12.6 22.8 1.7e+02 1.9 22.9 3.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PP_kinase_N PF13089.6 GAN01396.1 - 1.9 8.8 11.2 0.19 12.1 1.8 3.5 2 1 0 3 3 3 0 Polyphosphate kinase N-terminal domain NifQ PF04891.12 GAN01396.1 - 3.5 8.0 4.5 7.8 6.8 0.2 2.6 2 1 0 2 2 2 0 NifQ E1-E2_ATPase PF00122.20 GAN01397.1 - 5.3e-45 153.2 2.9 5.3e-45 153.2 2.9 3.5 5 0 0 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 GAN01397.1 - 1.5e-23 84.2 0.4 3.7e-23 82.9 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN01397.1 - 1.6e-13 50.1 0.0 6.2e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAN01397.1 - 0.0056 16.7 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAN01397.1 - 0.023 14.4 0.2 0.058 13.1 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 GAN01397.1 - 1.2 8.8 15.0 0.042 13.6 6.7 2.4 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus YEATS PF03366.16 GAN01398.1 - 9.2e-18 64.0 0.0 1.9e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 YEATS family SR-25 PF10500.9 GAN01398.1 - 0.048 13.3 11.1 0.072 12.7 11.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2987 PF11205.8 GAN01399.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) Chitin_synth_2 PF03142.15 GAN01402.1 - 1.4e-271 901.7 0.0 2e-271 901.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAN01402.1 - 1.9e-13 50.8 0.0 1.3e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN01402.1 - 6e-12 45.9 0.8 6e-12 45.9 0.8 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GAN01402.1 - 0.0019 17.7 0.0 0.031 13.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAN01402.1 - 0.011 15.5 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 RhoGEF PF00621.20 GAN01403.1 - 1.2e-31 110.4 0.1 3.1e-31 109.0 0.1 1.8 1 0 0 1 1 1 1 RhoGEF domain Peptidase_U40 PF10464.9 GAN01403.1 - 0.097 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase U40 GrpE PF01025.19 GAN01404.1 - 1.2e-42 145.4 2.9 1.5e-42 145.1 2.6 1.3 1 1 0 1 1 1 1 GrpE KapB PF08810.10 GAN01404.1 - 0.11 12.7 0.4 0.53 10.5 0.1 2.1 1 1 2 3 3 3 0 Kinase associated protein B DUF334 PF03904.13 GAN01404.1 - 0.19 11.2 1.3 0.25 10.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RNA_pol_Rpc4 PF05132.14 GAN01404.1 - 0.22 12.0 2.3 0.37 11.2 2.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2408 PF10303.9 GAN01404.1 - 0.22 12.1 3.3 0.35 11.4 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF5094 PF17015.5 GAN01404.1 - 0.37 10.9 4.2 0.36 10.9 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Methyltransf_32 PF13679.6 GAN01405.1 - 2.3e-30 105.7 0.1 3.4e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN01405.1 - 0.00074 20.2 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN01405.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAN01405.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 GAN01405.1 - 0.027 14.6 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 GAN01405.1 - 0.033 14.8 0.0 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAN01405.1 - 0.037 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 GAN01405.1 - 0.064 12.9 0.1 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Nodulation protein S (NodS) DREV PF05219.12 GAN01405.1 - 0.14 11.2 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 DREV methyltransferase Spc7 PF08317.11 GAN01406.1 - 2.2e-40 138.5 13.4 3.7e-40 137.7 13.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.12 GAN01406.1 - 0.51 11.0 7.9 2 9.1 2.1 3.7 2 1 0 2 2 2 0 SlyX DUF3037 PF11236.8 GAN01406.1 - 1 9.8 4.5 1.4 9.4 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) Baculo_PEP_C PF04513.12 GAN01406.1 - 2.1 8.4 5.9 2 8.4 1.3 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pro_CA PF00484.19 GAN01407.1 - 0.075 13.3 0.6 0.093 13.0 0.6 1.2 1 0 0 1 1 1 0 Carbonic anhydrase F-box-like PF12937.7 GAN01408.1 - 0.00048 20.0 1.2 0.0015 18.4 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN01408.1 - 0.0022 17.8 0.1 0.0022 17.8 0.1 3.3 4 0 0 4 4 4 1 F-box domain LRR_4 PF12799.7 GAN01408.1 - 0.0078 16.6 8.7 0.81 10.2 0.2 5.2 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) Colipase PF01114.18 GAN01408.1 - 0.054 13.2 1.8 0.12 12.0 1.8 1.5 1 0 0 1 1 1 0 Colipase, N-terminal domain RasGEF PF00617.19 GAN01409.1 - 2.6e-15 57.1 0.1 5.2e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain PAM2 PF07145.15 GAN01409.1 - 0.00044 19.7 0.2 0.0011 18.5 0.2 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Pox_A11 PF05061.13 GAN01409.1 - 1.2 8.3 7.1 2.2 7.5 7.1 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Bromodomain PF00439.25 GAN01410.1 - 1.5e-08 34.6 0.2 4.7e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Myb_DNA-binding PF00249.31 GAN01410.1 - 0.036 14.3 4.4 0.044 14.0 0.1 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN01410.1 - 0.073 13.3 0.3 0.26 11.6 0.3 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain PEX11 PF05648.14 GAN01411.1 - 8.4e-55 185.6 3.1 9.4e-55 185.5 3.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SNARE_assoc PF09335.11 GAN01412.1 - 1.6e-11 44.8 3.7 5.1e-10 39.9 4.1 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein MFS_MOT1 PF16983.5 GAN01412.1 - 1.7 9.1 7.2 12 6.3 2.1 2.4 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily SNARE_assoc PF09335.11 GAN01413.1 - 1e-08 35.7 6.0 2e-08 34.7 6.0 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4229 PF14012.6 GAN01413.1 - 0.091 12.9 2.3 0.91 9.7 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) PhoR PF11808.8 GAN01413.1 - 5.3 7.5 6.9 0.72 10.3 0.1 2.7 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR FAD_binding_1 PF00667.20 GAN01414.1 - 9.3e-65 218.3 0.0 1.6e-64 217.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.19 GAN01414.1 - 3.5e-24 85.8 3.3 6.3e-24 85.0 3.3 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_1 PF00175.21 GAN01414.1 - 7e-12 46.0 0.0 2.4e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 GAN01414.1 - 4.1e-06 27.0 0.0 1.4e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 GAN01414.1 - 0.0015 18.4 0.0 0.0047 16.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 GAN01414.1 - 0.1 12.9 0.1 0.99 9.8 0.0 2.5 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain Mito_carr PF00153.27 GAN01415.1 - 4.4e-40 135.5 1.8 7.4e-16 57.9 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 GAN01416.1 - 0.074 14.0 3.2 0.36 11.8 0.1 3.3 1 1 1 2 2 2 0 WD domain, G-beta repeat DUF533 PF04391.12 GAN01416.1 - 0.14 11.8 2.5 20 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) HrpB7 PF09486.10 GAN01416.1 - 0.67 10.3 4.2 7.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) MPC PF03650.13 GAN01417.1 - 6.8e-44 148.5 0.2 7.6e-44 148.4 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Glyco_transf_49 PF13896.6 GAN01418.1 - 9.8e-21 74.4 0.2 3.2e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl-transferase for dystroglycan Ceramidase PF05875.12 GAN01421.1 - 4.4e-51 173.8 23.5 5.4e-51 173.6 23.5 1.0 1 0 0 1 1 1 1 Ceramidase DUF1129 PF06570.11 GAN01421.1 - 0.021 14.3 0.4 0.04 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3272 PF11676.8 GAN01421.1 - 1.1 9.6 7.5 0.35 11.1 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3272) Gti1_Pac2 PF09729.9 GAN01422.1 - 3.7e-42 144.5 12.8 2.2e-37 128.9 0.2 2.9 2 1 1 3 3 3 2 Gti1/Pac2 family DUF1754 PF08555.10 GAN01423.1 - 3.7e-05 24.4 27.6 0.0003 21.5 23.0 2.5 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) RabGAP-TBC PF00566.18 GAN01423.1 - 0.0049 16.5 3.4 0.0055 16.4 3.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SopE_GEF PF07487.13 GAN01423.1 - 0.21 11.7 6.1 0.15 12.2 3.0 1.8 1 1 1 2 2 2 0 SopE GEF domain Frigida PF07899.11 GAN01423.1 - 0.23 10.7 9.3 0.31 10.3 9.3 1.1 1 0 0 1 1 1 0 Frigida-like protein PRP1_N PF06424.12 GAN01423.1 - 0.25 11.7 9.1 0.35 11.3 9.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Allexi_40kDa PF05549.11 GAN01423.1 - 0.26 10.8 3.2 0.3 10.6 3.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Exonuc_VII_L PF02601.15 GAN01423.1 - 0.62 9.6 7.6 0.67 9.5 7.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit ZYG-11_interact PF05884.12 GAN01423.1 - 0.85 9.0 2.9 1 8.7 2.9 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 LicD PF04991.13 GAN01423.1 - 2.3 8.3 8.2 2.7 8.1 8.2 1.0 1 0 0 1 1 1 0 LicD family Atrophin-1 PF03154.15 GAN01423.1 - 2.6 6.2 13.4 2.7 6.2 13.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF4061 PF13270.6 GAN01423.1 - 2.6 8.4 9.9 4.4 7.7 9.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) DUF724 PF05266.14 GAN01423.1 - 4.1 7.2 17.5 5.2 6.9 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CAF1A PF12253.8 GAN01424.1 - 1.5e-26 92.3 3.1 1.5e-26 92.3 3.1 3.4 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 GAN01424.1 - 0.0004 20.1 40.3 0.00073 19.3 40.3 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal eIF3_subunit PF08597.10 GAN01424.1 - 0.0015 18.5 22.1 0.0015 18.5 22.1 2.0 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit Macoilin PF09726.9 GAN01424.1 - 0.044 12.3 15.3 0.084 11.4 15.3 1.6 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 GAN01424.1 - 0.1 11.1 26.9 0.15 10.5 26.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP70 PF00012.20 GAN01424.1 - 0.34 9.0 16.3 0.52 8.4 16.3 1.3 1 0 0 1 1 1 0 Hsp70 protein LicD PF04991.13 GAN01424.1 - 0.78 9.8 12.8 1.7 8.8 12.8 1.5 1 0 0 1 1 1 0 LicD family GPCR_chapero_1 PF11904.8 GAN01424.1 - 0.81 9.1 17.8 1.4 8.3 17.8 1.3 1 0 0 1 1 1 0 GPCR-chaperone Draxin PF15550.6 GAN01424.1 - 4.9 6.9 25.9 0.81 9.5 21.6 1.7 2 0 0 2 2 2 0 Draxin GAGA_bind PF06217.12 GAN01424.1 - 4.9 7.3 16.7 8.4 6.6 16.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 GAN01424.1 - 8.3 4.6 26.6 15 3.7 26.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3402 PF11882.8 GAN01425.1 - 1.7e-84 284.6 28.2 1.1e-49 169.9 3.2 4.2 1 1 2 4 4 4 3 Domain of unknown function (DUF3402) N1221 PF07923.13 GAN01425.1 - 2.9e-34 118.6 1.4 2.9e-34 118.6 1.4 2.5 2 0 0 2 2 2 1 N1221-like protein Abhydrolase_1 PF00561.20 GAN01425.1 - 6.5e-19 68.6 0.3 1.3e-18 67.6 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 GAN01425.1 - 7.3e-16 57.5 0.1 1.9e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 GAN01425.1 - 0.0011 18.3 0.0 0.03 13.6 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FAM176 PF14851.6 GAN01425.1 - 0.24 11.0 6.3 3.3 7.4 3.8 2.9 2 0 0 2 2 2 0 FAM176 family rRNA_processing PF08524.11 GAN01425.1 - 1.9 8.5 8.9 0.17 11.9 3.0 2.3 2 0 0 2 2 2 0 rRNA processing KCH PF16944.5 GAN01426.1 - 9.6e-79 264.7 12.1 1.3e-78 264.3 12.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel Baculo_11_kDa PF06143.11 GAN01426.1 - 3.9 7.1 5.1 10 5.8 0.3 3.0 3 1 0 3 3 3 0 Baculovirus 11 kDa family TFIIS_C PF01096.18 GAN01427.1 - 2.2e-13 49.8 10.5 5.9e-13 48.4 0.6 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAN01427.1 - 9.3e-11 41.4 12.0 1.6e-10 40.6 7.4 2.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit CpXC PF14353.6 GAN01427.1 - 0.028 14.5 1.9 2.6 8.1 0.2 2.2 2 0 0 2 2 2 0 CpXC protein Ogr_Delta PF04606.12 GAN01427.1 - 0.087 12.8 0.5 0.087 12.8 0.5 2.6 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Elf1 PF05129.13 GAN01427.1 - 0.13 12.4 3.4 6.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_13 PF09855.9 GAN01427.1 - 0.14 12.3 2.8 10 6.4 0.3 2.6 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF3716 PF12511.8 GAN01427.1 - 0.26 11.4 9.6 0.16 12.1 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) zinc_ribbon_4 PF13717.6 GAN01427.1 - 0.61 10.0 0.2 0.61 10.0 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 GAN01427.1 - 6.7 6.8 11.5 4.5 7.4 1.3 3.0 1 1 1 2 2 2 0 Transposase zinc-binding domain Methyltransf_25 PF13649.6 GAN01428.1 - 2.2e-05 25.1 0.0 4.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAN01428.1 - 0.00026 20.4 0.1 0.00036 19.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 GAN01428.1 - 0.0012 19.4 0.0 0.0027 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN01428.1 - 0.0026 17.6 0.1 0.0044 16.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN01428.1 - 0.013 15.3 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain N-Term_TEN PF11474.8 GAN01428.1 - 0.024 14.2 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Methyltransf_12 PF08242.12 GAN01428.1 - 0.092 13.5 0.1 0.84 10.4 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Aconitase PF00330.20 GAN01430.1 - 1.5e-163 545.1 0.0 1.8e-163 544.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAN01430.1 - 1.2e-40 138.8 0.0 3.3e-40 137.4 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Aconitase PF00330.20 GAN01431.1 - 1.1e-136 456.5 0.0 1.4e-136 456.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAN01431.1 - 4.7e-39 133.7 0.0 9.7e-39 132.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_hydro38C2 PF17677.1 GAN01431.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain SET PF00856.28 GAN01432.1 - 2.3e-05 24.9 0.0 4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAN01432.1 - 0.0016 18.5 14.7 0.0039 17.3 14.7 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 GAN01432.1 - 0.18 12.1 11.5 0.41 11.0 11.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF4448 PF14610.6 GAN01433.1 - 7e-06 25.9 2.3 2.1e-05 24.4 2.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 GAN01433.1 - 0.0012 18.7 0.6 0.003 17.5 0.6 1.6 1 0 0 1 1 1 1 TMEM154 protein family Claudin_2 PF13903.6 GAN01433.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4690 PF15756.5 GAN01433.1 - 0.014 16.0 0.1 0.041 14.5 0.1 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Orf78 PF06024.12 GAN01433.1 - 0.028 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF4064 PF13273.6 GAN01433.1 - 0.049 13.9 0.2 0.094 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) SCF PF02404.15 GAN01433.1 - 0.13 11.5 1.3 0.21 10.9 1.3 1.2 1 0 0 1 1 1 0 Stem cell factor RIFIN PF02009.16 GAN01433.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Rifin DUF1180 PF06679.12 GAN01433.1 - 0.47 10.8 4.3 0.11 12.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Secretin_N_2 PF07655.13 GAN01433.1 - 2.1 8.9 20.2 0.15 12.7 12.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Endomucin PF07010.12 GAN01433.1 - 3.7 7.5 14.4 0.16 12.0 6.8 2.0 2 0 0 2 2 2 0 Endomucin SH2_2 PF14633.6 GAN01436.1 - 3.5e-70 235.8 0.1 1.3e-69 233.9 0.0 2.1 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 GAN01436.1 - 2.7e-33 114.9 0.1 9e-33 113.2 0.1 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 GAN01436.1 - 3.5e-29 101.5 1.0 9.5e-29 100.2 1.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 GAN01436.1 - 3.7e-27 94.7 0.0 8.2e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 GAN01436.1 - 2.6e-17 63.2 25.6 2.6e-17 63.2 25.6 6.1 3 1 2 5 5 2 1 Acidic N-terminal SPT6 Tex_YqgF PF16921.5 GAN01436.1 - 3.1e-06 27.7 0.1 7.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain S1 PF00575.23 GAN01436.1 - 9.5e-06 25.9 0.1 3.1e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 GAN01436.1 - 1.5e-05 25.0 0.0 4.4e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 GAN01436.1 - 2.2e-05 24.6 0.0 0.0003 21.0 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_9 PF17674.1 GAN01436.1 - 0.00021 22.1 0.3 0.0023 18.8 0.3 3.0 1 1 0 1 1 1 1 HHH domain Tex_N PF09371.10 GAN01436.1 - 0.0018 18.0 0.4 0.11 12.2 0.0 3.2 3 0 0 3 3 3 1 Tex-like protein N-terminal domain PT-HINT PF07591.11 GAN01436.1 - 0.0037 17.5 0.0 0.059 13.6 0.0 2.5 2 0 0 2 2 2 1 Pretoxin HINT domain DUF755 PF05501.11 GAN01437.1 - 0.2 11.9 10.8 0.3 11.4 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Macoilin PF09726.9 GAN01437.1 - 0.38 9.3 5.0 0.36 9.3 5.0 1.0 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 GAN01438.1 - 0.016 15.8 1.6 0.021 15.5 1.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Extensin_2 PF04554.13 GAN01438.1 - 0.078 13.1 19.5 0.13 12.4 19.5 1.3 1 0 0 1 1 1 0 Extensin-like region Mucin PF01456.17 GAN01439.1 - 0.018 15.0 15.0 0.02 14.9 15.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.6 GAN01439.1 - 5.2 7.0 9.3 7.1 6.5 9.3 1.3 1 1 0 1 1 1 0 TMEM154 protein family NAC PF01849.18 GAN01442.1 - 1.8e-22 79.0 0.5 7.2e-22 77.1 0.0 2.3 3 0 0 3 3 3 1 NAC domain DUF1217 PF06748.12 GAN01442.1 - 0.045 13.8 0.6 0.086 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) Peptidase_C48 PF02902.19 GAN01443.1 - 5e-11 42.9 0.2 7.2e-10 39.1 0.2 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ecl1 PF12855.7 GAN01444.1 - 5.2e-08 34.3 19.8 1.2e-07 33.1 19.8 1.5 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 GAN01444.1 - 0.79 9.9 6.4 1.8 8.7 6.4 1.5 1 1 0 1 1 1 0 MYND finger Ribosomal_L3 PF00297.22 GAN01445.1 - 2.3e-30 105.8 1.4 2.7e-30 105.6 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Ubiq_cyt_C_chap PF03981.12 GAN01446.1 - 7.4e-35 120.1 0.1 1.3e-34 119.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone NIF PF03031.18 GAN01447.1 - 2.3e-26 92.4 0.3 3.6e-26 91.8 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ESCRT-II PF05871.12 GAN01447.1 - 0.0097 16.2 0.7 0.017 15.4 0.7 1.4 1 0 0 1 1 1 1 ESCRT-II complex subunit NT-C2 PF10358.9 GAN01448.1 - 3.2e-26 91.8 0.0 5.8e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L37e PF01907.19 GAN01449.1 - 3.3e-27 94.4 11.4 5.8e-27 93.6 11.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.19 GAN01449.1 - 0.021 14.9 1.0 0.029 14.4 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 GAN01449.1 - 0.033 14.2 3.3 0.052 13.6 3.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.6 GAN01449.1 - 0.082 12.9 4.1 0.14 12.2 4.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DNA_RNApol_7kD PF03604.13 GAN01449.1 - 0.26 11.0 4.4 1.2 8.9 0.9 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC4_2 PF13923.6 GAN01449.1 - 0.73 9.7 5.0 1.3 9.0 5.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_13 PF09855.9 GAN01449.1 - 2.7 8.2 5.9 36 4.6 0.2 3.1 1 1 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Cse1 PF08506.10 GAN01450.1 - 1.2e-05 24.4 1.2 0.00019 20.4 0.7 2.9 3 1 0 3 3 3 1 Cse1 DRIM PF07539.12 GAN01450.1 - 7.3e-05 21.3 0.6 0.3 9.4 0.1 3.5 2 1 2 4 4 4 2 Down-regulated in metastasis Cnd1 PF12717.7 GAN01450.1 - 0.0024 17.9 0.1 0.12 12.4 0.0 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAN01450.1 - 0.0048 17.0 0.3 39 4.9 0.0 5.1 4 1 1 5 5 5 0 HEAT repeat MMS19_C PF12460.8 GAN01450.1 - 0.0089 15.2 1.1 1.9 7.5 0.2 2.6 2 1 0 2 2 2 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 GAN01450.1 - 0.0093 16.1 0.9 5.5 7.2 0.0 4.7 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 GAN01450.1 - 0.049 13.7 2.3 0.63 10.1 0.0 3.6 3 1 0 3 3 3 0 Exportin 1-like protein RsbU_N PF08673.10 GAN01450.1 - 0.07 13.2 0.4 1.3 9.2 0.0 3.2 4 0 0 4 4 4 0 Phosphoserine phosphatase RsbU, N-terminal domain HEAT_EZ PF13513.6 GAN01450.1 - 0.11 13.0 0.1 3.3e+02 1.9 0.0 4.9 4 1 1 5 5 5 0 HEAT-like repeat Profilin PF00235.19 GAN01452.1 - 2e-51 173.5 0.4 2.3e-51 173.4 0.4 1.0 1 0 0 1 1 1 1 Profilin ThiF PF00899.21 GAN01453.1 - 6.6e-109 362.9 0.0 3.7e-77 259.0 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAN01453.1 - 7.2e-93 311.1 0.2 1.6e-92 310.0 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAN01453.1 - 2.2e-38 130.8 0.7 5.5e-38 129.6 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 GAN01453.1 - 3.4e-33 113.7 0.2 7.6e-33 112.5 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 GAN01453.1 - 2.8e-25 88.3 0.5 6.4e-25 87.1 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Pkinase PF00069.25 GAN01455.1 - 6.5e-61 206.0 0.0 1.1e-60 205.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01455.1 - 5.1e-46 157.1 0.0 7.7e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN01455.1 - 0.00013 21.4 0.1 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 GAN01455.1 - 0.00032 20.4 0.5 0.00062 19.4 0.5 1.5 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 GAN01455.1 - 0.014 15.0 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 GAN01455.1 - 0.052 12.9 0.3 0.094 12.1 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 GAN01455.1 - 0.24 11.8 10.2 0.61 10.5 10.2 1.8 1 0 0 1 1 1 0 Ring finger domain PAS_3 PF08447.12 GAN01457.1 - 2.4e-12 47.0 3.9 4e-12 46.3 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 GAN01457.1 - 9.6e-09 35.2 2.9 1.2e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 GAN01457.1 - 3e-05 24.2 0.0 8.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 GAN01457.1 - 3.2e-05 24.2 2.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold Cyclin_N PF00134.23 GAN01457.1 - 4.4e-05 23.2 0.0 4.4e-05 23.2 0.0 2.9 2 1 1 3 3 3 1 Cyclin, N-terminal domain Mucin PF01456.17 GAN01457.1 - 0.0053 16.7 20.3 0.0053 16.7 20.3 2.4 2 0 0 2 2 2 1 Mucin-like glycoprotein Cyclin PF08613.11 GAN01457.1 - 0.0078 16.6 21.0 0.0078 16.6 14.2 3.7 2 1 0 2 2 2 1 Cyclin Sporozoite_P67 PF05642.11 GAN01457.1 - 0.16 10.0 4.3 0.25 9.4 4.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAT1 PF09770.9 GAN01457.1 - 1.7 6.9 30.0 2.9 6.1 30.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cys_Met_Meta_PP PF01053.20 GAN01459.1 - 7.6e-146 485.5 0.0 8.6e-146 485.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAN01459.1 - 4.2e-12 45.9 0.0 6.4e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAN01459.1 - 3.7e-11 42.6 0.1 5.5e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAN01459.1 - 1.7e-07 30.9 0.1 3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 GAN01459.1 - 0.00014 20.5 0.0 0.00021 19.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 GAN01459.1 - 0.00018 20.9 0.0 0.00081 18.7 0.0 1.8 1 1 0 2 2 2 1 Beta-eliminating lyase GDC-P PF02347.16 GAN01459.1 - 0.0062 15.4 0.0 0.0087 14.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Metallophos PF00149.28 GAN01460.1 - 1.4e-09 38.8 3.5 1.4e-09 38.8 3.5 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase APG5 PF04106.12 GAN01461.1 - 6.3e-51 173.2 0.6 2e-50 171.5 0.6 1.8 1 1 0 1 1 1 1 Autophagy protein Apg5 Homeobox_KN PF05920.11 GAN01462.1 - 1.7e-18 66.2 1.4 3.4e-18 65.3 0.3 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 GAN01462.1 - 1e-08 34.9 0.6 2.6e-08 33.6 0.6 1.7 1 0 0 1 1 1 1 Homeodomain UPF0449 PF15136.6 GAN01462.1 - 0.49 10.9 5.6 0.68 10.4 3.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 RhoGAP PF00620.27 GAN01463.1 - 3.8e-08 33.3 0.1 1.2e-07 31.7 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain Peptidase_C34 PF05413.11 GAN01463.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase PaaA_PaaC PF05138.12 GAN01463.1 - 0.075 12.2 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein Ribosomal_L31 PF01197.18 GAN01463.1 - 0.29 11.4 0.1 0.29 11.4 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L31 DEAD PF00270.29 GAN01464.1 - 2.3e-36 125.2 0.3 1.2e-35 122.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN01464.1 - 2e-29 102.2 0.5 6e-29 100.6 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PrpR_N PF06506.11 GAN01464.1 - 0.0035 16.9 0.3 1.1 8.8 0.0 3.1 3 0 0 3 3 3 1 Propionate catabolism activator AAA_30 PF13604.6 GAN01464.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAN01464.1 - 0.071 13.4 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.21 GAN01464.1 - 0.22 11.1 2.7 12 5.4 0.0 2.8 3 0 0 3 3 3 0 Snf7 HAD_2 PF13419.6 GAN01465.1 - 2e-20 73.6 0.1 6.9e-20 71.9 0.1 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN01465.1 - 1.5e-14 54.8 0.0 1.9e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN01465.1 - 1.6e-08 34.5 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAN01465.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peroxin-22 PF12827.7 GAN01467.1 - 0.00071 19.5 0.2 0.00098 19.0 0.2 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family Asp PF00026.23 GAN01468.1 - 1.1e-57 195.9 1.2 1.4e-57 195.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN01468.1 - 2.2e-08 34.5 2.6 1.5e-06 28.6 2.6 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAN01469.1 - 2.2e-69 234.3 9.5 2.5e-67 227.5 9.5 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN01469.1 - 1.5e-15 57.9 5.3 3.9e-14 53.3 2.1 4.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN01469.1 - 0.0015 18.3 0.1 0.047 13.5 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAN01469.1 - 0.052 14.2 2.2 4.6 7.9 0.1 3.5 2 2 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GAN01469.1 - 0.059 13.9 0.4 2.2 8.9 0.1 3.1 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 GAN01470.1 - 3.7e-64 217.1 3.7 4.3e-64 216.9 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN01470.1 - 4.4e-16 59.6 1.4 1.2e-13 51.7 0.4 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN01470.1 - 0.11 12.3 0.3 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Asp PF00026.23 GAN01471.1 - 6.4e-68 229.5 4.4 7.4e-68 229.3 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN01471.1 - 1.8e-15 57.6 6.2 1.8e-09 38.1 0.2 3.7 2 2 1 3 3 3 3 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN01471.1 - 0.0014 18.4 0.6 0.012 15.4 0.6 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAN01471.1 - 0.042 14.5 0.4 1.6 9.4 0.1 2.9 2 1 0 2 2 2 0 Aspartyl protease adh_short_C2 PF13561.6 GAN01473.1 - 2.8e-48 164.5 0.3 3.9e-48 164.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN01473.1 - 3.5e-47 160.4 0.2 5e-47 159.9 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAN01473.1 - 7.1e-10 39.1 0.2 1.4e-09 38.1 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAN01473.1 - 0.019 14.4 0.1 0.051 13.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF202 PF02656.15 GAN01474.1 - 7.6e-20 71.1 0.0 7.6e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) F-box-like PF12937.7 GAN01474.1 - 6.9e-09 35.5 0.2 1.7e-08 34.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN01474.1 - 0.00018 21.3 0.6 0.0004 20.2 0.6 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 GAN01475.1 - 3.5e-65 214.4 23.2 2.5e-10 40.8 0.3 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN01475.1 - 2.4e-21 75.8 0.6 7.1e-07 29.4 0.1 5.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN01475.1 - 9.8e-11 41.0 6.4 0.0062 15.2 0.0 6.2 3 2 3 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 GAN01475.1 - 4.1e-06 26.8 0.3 0.15 11.9 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 GAN01475.1 - 9.2e-06 24.7 2.5 0.13 11.0 0.0 4.3 2 1 3 5 5 5 3 Nup133 N terminal like DUF4988 PF16378.5 GAN01475.1 - 0.0011 18.6 0.1 9.5 5.8 0.0 3.7 3 1 1 4 4 4 2 Domain of unknown function nos_propeller PF18764.1 GAN01475.1 - 0.0016 18.3 0.0 8.8 6.3 0.0 3.9 3 1 1 4 4 4 1 Nitrous oxide reductase propeller repeat Cytochrom_D1 PF02239.16 GAN01475.1 - 0.0062 15.1 0.1 1.5 7.3 0.0 3.0 2 1 0 3 3 3 1 Cytochrome D1 heme domain LisH PF08513.11 GAN01475.1 - 0.053 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 LisH SET PF00856.28 GAN01476.1 - 2e-06 28.3 0.0 3.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 SET domain PRP38 PF03371.15 GAN01477.1 - 9.7e-48 162.3 0.5 1.7e-47 161.5 0.5 1.4 1 0 0 1 1 1 1 PRP38 family Presenilin PF01080.17 GAN01477.1 - 9 4.9 6.6 14 4.3 6.6 1.3 1 0 0 1 1 1 0 Presenilin PI3_PI4_kinase PF00454.27 GAN01478.1 - 2.1e-40 139.1 0.0 2e-38 132.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAN01478.1 - 1e-23 83.7 0.0 3.8e-23 81.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Potex_coat PF06184.11 GAN01478.1 - 0.071 12.7 0.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Potexvirus coat protein Methyltransf_28 PF02636.17 GAN01479.1 - 2.9e-36 125.4 0.0 4.4e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 GAN01479.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 GAN01479.1 - 0.08 13.7 0.0 0.27 12.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 GAN01479.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_1 PF00076.22 GAN01480.1 - 1.8e-09 37.3 0.0 3.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN01480.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif C2 PF00168.30 GAN01481.1 - 1.2e-07 32.0 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain UBA PF00627.31 GAN01481.1 - 3.2e-06 26.9 0.7 8.5e-06 25.6 0.7 1.7 1 0 0 1 1 1 1 UBA/TS-N domain C2-C2_1 PF11618.8 GAN01481.1 - 4.3e-06 26.9 0.0 9.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 UBA_4 PF14555.6 GAN01481.1 - 0.0012 18.6 0.1 0.0041 16.9 0.1 2.0 2 0 0 2 2 2 1 UBA-like domain DUF1771 PF08590.10 GAN01481.1 - 0.85 10.0 5.1 1.2 9.6 1.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) CDC45 PF02724.14 GAN01484.1 - 0.00024 19.5 18.4 0.00025 19.5 18.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GAN01484.1 - 0.0017 16.7 30.3 0.002 16.5 30.3 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GAN01484.1 - 0.003 17.0 31.5 0.004 16.6 31.5 1.1 1 0 0 1 1 1 1 SDA1 Raftlin PF15250.6 GAN01484.1 - 0.095 11.4 4.1 0.15 10.8 4.1 1.2 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.10 GAN01484.1 - 0.11 11.8 28.3 0.14 11.4 28.3 1.2 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.12 GAN01484.1 - 0.37 9.1 14.3 0.46 8.7 14.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SLC12 PF03522.15 GAN01484.1 - 0.46 9.5 4.0 0.61 9.0 4.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 GAN01484.1 - 0.62 10.4 11.9 1.4 9.2 11.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 GAN01484.1 - 0.64 9.2 4.7 0.82 8.8 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GAN01484.1 - 9.3 4.9 7.1 12 4.5 7.1 1.3 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 GAN01484.1 - 9.6 5.5 29.4 21 4.4 29.4 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Abhydrolase_6 PF12697.7 GAN01486.1 - 5.4e-06 27.2 0.6 8.5e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 GAN01486.1 - 4.8e-05 23.4 0.1 0.00024 21.1 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 GAN01486.1 - 8.6e-05 22.3 0.3 0.00021 21.0 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN01486.1 - 0.0016 17.7 0.3 0.004 16.4 0.3 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAN01486.1 - 0.024 14.5 0.0 0.25 11.2 0.0 2.5 3 0 0 3 3 3 0 Serine hydrolase Thioesterase PF00975.20 GAN01486.1 - 0.032 14.4 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 GAN01486.1 - 0.035 13.9 0.0 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ndr PF03096.14 GAN01486.1 - 0.044 12.5 0.0 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family TAF4 PF05236.14 GAN01487.1 - 0.00049 19.9 11.0 0.0007 19.4 11.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Pex26 PF07163.12 GAN01487.1 - 0.00092 18.6 0.7 0.00092 18.6 0.7 3.0 2 1 1 3 3 2 1 Pex26 protein DUF5401 PF17380.2 GAN01487.1 - 0.0043 15.2 19.3 0.0052 14.9 19.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5401) CDC45 PF02724.14 GAN01487.1 - 0.013 13.8 11.1 0.019 13.3 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 GAN01487.1 - 0.024 14.2 19.8 0.038 13.6 19.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Plasmodium_Vir PF05795.11 GAN01487.1 - 0.026 14.0 4.2 0.042 13.3 4.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 GAN01487.1 - 0.046 10.9 8.4 0.058 10.5 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WDCP PF15390.6 GAN01487.1 - 0.36 9.1 11.1 0.35 9.2 9.6 1.6 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family Presenilin PF01080.17 GAN01487.1 - 0.46 9.2 9.3 0.64 8.7 9.3 1.3 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 GAN01487.1 - 0.5 8.2 9.9 0.69 7.7 9.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 GAN01487.1 - 0.82 8.1 20.2 1.1 7.7 20.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 GAN01487.1 - 1.5 8.6 18.9 2.4 7.9 18.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 GAN01487.1 - 1.7 7.3 10.7 2.4 6.8 10.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAJIN PF15077.6 GAN01487.1 - 1.9 8.2 14.2 2.9 7.6 14.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4407 PF14362.6 GAN01487.1 - 2.4 7.4 11.6 3.5 6.9 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp-B-Hydro_N PF05279.11 GAN01487.1 - 2.7 8.0 19.5 3.7 7.5 19.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RAMPs PF03787.15 GAN01487.1 - 4.1 7.4 5.3 6 6.8 5.3 1.2 1 0 0 1 1 1 0 RAMP superfamily Hid1 PF12722.7 GAN01487.1 - 4.7 5.2 14.9 5.7 4.9 14.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Atg14 PF10186.9 GAN01487.1 - 6 5.8 14.4 8.2 5.4 14.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF966 PF06136.13 GAN01487.1 - 8.3 6.0 17.7 11 5.6 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) VASt PF16016.5 GAN01488.1 - 1.6e-29 103.3 0.1 3.7e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 GAN01488.1 - 6.5e-29 101.3 3.3 6.5e-29 101.3 3.3 2.1 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 GAN01488.1 - 3.1e-11 43.7 1.1 1.4e-10 41.6 0.7 2.4 2 0 0 2 2 2 1 PH domain DDE_1 PF03184.19 GAN01488.1 - 0.057 13.1 0.0 17 5.0 0.0 2.7 2 0 0 2 2 2 0 DDE superfamily endonuclease Lyase_1 PF00206.20 GAN01489.1 - 1.4e-115 385.9 0.4 1.5e-113 379.3 0.1 2.5 2 1 0 2 2 2 1 Lyase FumaraseC_C PF10415.9 GAN01489.1 - 9.4e-23 80.4 0.0 1.9e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus SBP_bac_3 PF00497.20 GAN01489.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 RNase_PH PF01138.21 GAN01491.1 - 9.6e-35 120.0 0.1 1.6e-34 119.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAN01491.1 - 0.0036 17.3 0.3 0.0091 16.0 0.3 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 His_Phos_1 PF00300.22 GAN01492.1 - 3e-18 66.2 0.0 5.7e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AMP-binding PF00501.28 GAN01493.1 - 8.5e-98 327.7 0.0 1.1e-97 327.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN01493.1 - 0.0024 18.8 0.0 0.012 16.6 0.0 2.2 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain Nbl1_Borealin_N PF10444.9 GAN01494.1 - 5.4e-06 25.9 2.6 5.4e-06 25.9 2.6 1.9 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Adenyl_cycl_N PF12633.7 GAN01494.1 - 0.45 10.4 4.2 0.89 9.4 0.3 2.5 2 1 1 3 3 3 0 Adenylate cyclase NT domain DUF3135 PF11333.8 GAN01494.1 - 1.6 9.0 6.3 0.36 11.1 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Sugar_tr PF00083.24 GAN01495.1 - 5.5e-101 338.7 31.2 6.2e-101 338.5 31.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN01495.1 - 5.3e-23 81.5 49.4 1.6e-19 70.0 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf66_N PF07444.11 GAN01495.1 - 3.8 7.7 8.8 1 9.5 3.0 2.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus Herpes_Helicase PF02689.14 GAN01496.1 - 9.8e-06 23.8 0.1 1e-05 23.8 0.1 1.0 1 0 0 1 1 1 1 Helicase PHO4 PF01384.20 GAN01497.1 - 1e-118 396.3 20.1 1.3e-118 396.0 20.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family IPK PF03770.16 GAN01498.1 - 1.1e-49 169.0 0.0 2e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase UPF0183 PF03676.14 GAN01499.1 - 3.5e-100 336.1 0.4 2e-60 205.2 0.1 2.4 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) DUF1772 PF08592.11 GAN01500.1 - 1.3e-19 70.9 0.1 1.7e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TraA PF05513.11 GAN01500.1 - 0.004 17.5 0.0 0.0062 16.9 0.0 1.4 1 0 0 1 1 1 1 TraA DUF3919 PF13057.6 GAN01501.1 - 0.0009 18.9 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3919) RhoGAP PF00620.27 GAN01502.1 - 6.2e-41 139.7 0.0 1.3e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 GAN01502.1 - 7.7e-11 42.4 2.9 8.2e-10 39.1 0.0 3.5 3 0 0 3 3 3 1 PH domain PH_13 PF16652.5 GAN01502.1 - 0.25 11.2 4.6 0.91 9.3 0.1 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain FAM176 PF14851.6 GAN01502.1 - 2.3 7.9 6.1 0.73 9.5 0.1 3.1 3 1 0 3 3 3 0 FAM176 family ABC1 PF03109.16 GAN01503.1 - 1.6e-20 73.4 0.0 2.6e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family CSN8_PSD8_EIF3K PF10075.9 GAN01505.1 - 8.6e-27 93.9 0.3 1.1e-26 93.5 0.3 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family UFC1 PF08694.11 GAN01506.1 - 0.049 13.3 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sec2p PF06428.11 GAN01507.1 - 1.3e-11 44.3 10.7 1.3e-11 44.3 10.7 2.5 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Sgf11 PF08209.11 GAN01507.1 - 0.4 10.3 3.0 9.9 5.8 0.4 2.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CC2-LZ PF16516.5 GAN01507.1 - 1.9 8.9 14.5 7.6 7.0 4.1 2.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF641 PF04859.12 GAN01507.1 - 4.5 7.6 10.6 0.91 9.9 0.5 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3439 PF11921.8 GAN01508.1 - 0.093 12.7 1.4 0.12 12.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_4 PF13894.6 GAN01508.1 - 0.16 12.9 1.8 3 8.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN01508.1 - 3.1 7.9 7.0 0.34 11.0 1.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger RhoGEF PF00621.20 GAN01510.1 - 1.2e-15 58.2 0.8 3e-15 56.9 0.8 1.5 1 0 0 1 1 1 1 RhoGEF domain MG2 PF01835.19 GAN01511.1 - 0.08 13.4 0.5 56 4.3 0.0 4.5 4 1 1 5 5 5 0 MG2 domain DUF3060 PF11259.8 GAN01511.1 - 5.6 6.7 13.3 4.9 6.9 7.2 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3060) ADK PF00406.22 GAN01513.1 - 2e-57 193.5 0.0 2.3e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAN01513.1 - 6.4e-22 78.5 0.0 1.7e-21 77.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 GAN01513.1 - 9.4e-18 63.9 0.0 1.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAN01513.1 - 1.2e-05 25.8 0.0 2.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 GAN01513.1 - 4e-05 24.0 0.9 0.0051 17.1 0.1 2.2 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 GAN01513.1 - 0.0016 18.2 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 GAN01513.1 - 0.0096 16.1 0.0 0.043 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAN01513.1 - 0.02 14.6 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 GAN01513.1 - 0.029 14.7 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 GAN01513.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 GAN01513.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAN01513.1 - 0.18 12.2 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DeoC PF01791.9 GAN01514.1 - 8e-17 61.6 1.2 9.9e-17 61.3 1.2 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 GAN01514.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 GAN01514.1 - 0.059 12.4 0.0 0.17 10.9 0.0 1.5 1 1 1 2 2 2 0 FMN-dependent dehydrogenase Lipase_GDSL_3 PF14606.6 GAN01514.1 - 0.06 13.5 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Prenyltransf PF01255.19 GAN01514.1 - 0.07 12.6 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase BCS1_N PF08740.11 GAN01515.1 - 8.3e-40 136.8 0.0 1.1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAN01515.1 - 1.7e-21 77.0 0.0 5.6e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GAN01515.1 - 0.0033 16.6 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAN01515.1 - 0.027 14.6 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAN01515.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAN01515.1 - 0.034 14.7 0.2 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAN01515.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 GAN01515.1 - 0.12 12.8 0.0 0.28 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GAN01515.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAN01515.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PALP PF00291.25 GAN01516.1 - 8.1e-61 206.0 0.1 1e-60 205.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme pPIWI_RE_REase PF18154.1 GAN01516.1 - 0.04 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 REase associating with pPIWI_RE WD40 PF00400.32 GAN01517.1 - 0.0037 18.1 16.3 0.045 14.6 0.0 5.4 3 2 1 4 4 4 1 WD domain, G-beta repeat CPSF_A PF03178.15 GAN01517.1 - 0.014 14.8 0.1 0.049 12.9 0.0 1.7 1 1 0 2 2 2 0 CPSF A subunit region Tetraspanin PF00335.20 GAN01518.1 - 6.5e-12 45.7 5.1 8.7e-12 45.2 5.1 1.2 1 0 0 1 1 1 1 Tetraspanin family La PF05383.17 GAN01519.1 - 4.4e-21 74.7 0.0 1.3e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 La domain SelP_N PF04592.14 GAN01519.1 - 0.6 9.5 6.2 2.2 7.6 6.2 2.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RVP_2 PF08284.11 GAN01521.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease E1-E2_ATPase PF00122.20 GAN01522.1 - 2e-51 174.1 0.2 2e-51 174.1 0.2 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN01522.1 - 8.6e-49 165.7 5.8 8.6e-49 165.7 5.8 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAN01522.1 - 1.1e-21 78.2 1.8 7.1e-21 75.5 1.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN01522.1 - 3.1e-16 59.2 0.0 6.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN01522.1 - 8.1e-16 57.5 0.0 1.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN01522.1 - 9.4e-07 28.8 4.5 0.012 15.4 2.3 3.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN01522.1 - 0.0093 16.4 0.0 0.16 12.4 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 GAN01522.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CoA_binding_2 PF13380.6 GAN01522.1 - 0.14 12.6 0.1 0.79 10.2 0.0 2.2 2 1 0 2 2 2 0 CoA binding domain adh_short PF00106.25 GAN01523.1 - 2.5e-32 111.9 0.8 1.4e-30 106.2 0.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN01523.1 - 2.6e-20 73.0 0.1 1.2e-18 67.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN01523.1 - 8.6e-06 25.8 0.1 1.3e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.6 GAN01523.1 - 0.092 12.0 0.1 0.15 11.3 0.1 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 GAN01523.1 - 0.11 11.8 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GAN01523.1 - 0.13 11.7 0.2 0.21 11.0 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-C2H2_2 PF12756.7 GAN01524.1 - 0.0002 21.7 2.2 0.00075 19.8 2.2 2.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN01524.1 - 0.00072 20.2 10.8 0.024 15.5 2.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 GAN01524.1 - 0.017 15.4 9.6 0.12 12.7 2.4 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_10 PF18414.1 GAN01524.1 - 0.088 12.4 1.8 0.22 11.1 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2H2 PF00096.26 GAN01524.1 - 0.11 13.0 10.8 0.22 12.1 3.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 GAN01524.1 - 0.95 9.4 6.8 0.094 12.6 1.5 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 GAN01524.1 - 2 9.1 8.0 0.37 11.5 1.4 3.0 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats Glyco_hydro_47 PF01532.20 GAN01526.1 - 1.1e-134 449.8 3.9 1.3e-134 449.6 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 GAN01526.1 - 0.00094 17.8 1.2 0.68 8.4 0.0 2.5 1 1 1 3 3 3 2 Beta-L-arabinofuranosidase, GH127 DUF1713 PF08213.11 GAN01527.1 - 2.2e-14 53.1 20.5 3.4e-14 52.5 20.5 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ribosomal_S13 PF00416.22 GAN01528.1 - 5e-53 178.9 2.6 5.7e-53 178.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAN01528.1 - 0.0083 14.9 0.0 0.012 14.4 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 GAN01528.1 - 0.061 12.3 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DUF2746 PF10874.8 GAN01528.1 - 0.094 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) adh_short PF00106.25 GAN01529.1 - 1e-20 74.0 0.0 2.1e-20 73.1 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN01529.1 - 5e-10 39.3 0.0 6.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN01529.1 - 1.8e-05 24.7 0.1 2.7e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN01529.1 - 8.3e-05 22.2 0.0 0.00016 21.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAN01529.1 - 0.0026 17.7 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAN01529.1 - 0.0094 15.1 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAN01529.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UDPGT PF00201.18 GAN01530.1 - 8.9e-29 100.6 0.1 7.8e-28 97.5 0.1 2.0 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN01530.1 - 6.1e-11 42.6 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 GAN01530.1 - 0.067 13.2 0.0 0.55 10.3 0.0 2.3 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain pXO2-34 PF17362.2 GAN01530.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function F-box-like PF12937.7 GAN01531.1 - 2.3e-06 27.4 0.1 5.6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like TbpB_C PF17483.2 GAN01531.1 - 0.014 15.8 0.6 6.9 7.1 0.0 2.5 1 1 1 2 2 2 0 C-lobe handle domain of Tf-binding protein B F-box PF00646.33 GAN01531.1 - 0.21 11.5 2.2 1.4 8.9 2.2 2.3 1 1 0 1 1 1 0 F-box domain E1-E2_ATPase PF00122.20 GAN01532.1 - 1.8e-48 164.4 5.2 1.8e-48 164.4 5.2 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN01532.1 - 2.3e-28 99.1 0.9 2.3e-28 99.1 0.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAN01532.1 - 3.1e-20 72.0 0.0 6.5e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN01532.1 - 4.6e-18 66.3 0.1 5.1e-16 59.6 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN01532.1 - 1.7e-14 53.2 0.1 5.7e-13 48.4 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN01532.1 - 6e-05 22.9 0.5 0.0047 16.7 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NVEALA PF14055.6 GAN01532.1 - 0.016 15.2 0.0 0.016 15.2 0.0 3.7 3 1 1 4 4 4 0 NVEALA protein DUF4181 PF13789.6 GAN01532.1 - 0.57 10.5 10.6 12 6.2 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) Presenilin PF01080.17 GAN01533.1 - 1.5e-123 412.5 7.6 2.2e-123 412.0 7.6 1.2 1 0 0 1 1 1 1 Presenilin zf-MYND PF01753.18 GAN01533.1 - 0.0067 16.5 9.0 0.011 15.8 9.0 1.3 1 0 0 1 1 1 1 MYND finger Zn_clus PF00172.18 GAN01534.1 - 1.7e-08 34.4 11.5 2.9e-08 33.7 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1336 PF07059.12 GAN01534.1 - 0.04 14.0 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Met_10 PF02475.16 GAN01535.1 - 1.6e-72 243.4 0.2 2.3e-72 242.9 0.2 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 GAN01535.1 - 3.2e-05 23.5 0.1 0.00027 20.4 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 GAN01535.1 - 0.00041 19.7 0.1 0.00056 19.2 0.1 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.7 GAN01535.1 - 0.004 17.1 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 GAN01535.1 - 0.081 12.6 0.2 5 6.7 0.0 2.4 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Catalase PF00199.19 GAN01536.1 - 4.1e-201 668.0 0.4 4.9e-201 667.8 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAN01536.1 - 3.1e-23 81.7 0.2 9e-23 80.3 0.1 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Oxidored_FMN PF00724.20 GAN01537.1 - 3e-102 342.4 0.0 3.6e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HAMP PF00672.25 GAN01538.1 - 5.6e-113 369.3 52.3 8e-08 32.5 0.0 17.9 18 0 0 18 18 17 15 HAMP domain HTH_6 PF01418.17 GAN01538.1 - 1.6e-12 47.2 5.7 18 5.4 0.0 13.1 12 1 1 13 13 13 0 Helix-turn-helix domain, rpiR family SpoIIID PF12116.8 GAN01538.1 - 1e-06 28.7 28.9 1.6 8.9 0.0 12.4 13 0 0 13 13 13 1 Stage III sporulation protein D HMG_box PF00505.19 GAN01538.1 - 2.6e-05 24.5 0.0 27 5.3 0.0 6.8 7 0 0 7 7 7 0 HMG (high mobility group) box PhoR PF11808.8 GAN01538.1 - 0.00085 19.7 0.0 61 4.1 0.0 6.9 9 0 0 9 9 7 0 Phosphate regulon sensor protein PhoR Vac_Fusion PF02346.16 GAN01538.1 - 0.0013 18.3 4.3 1.1e+02 2.5 0.0 9.2 11 0 0 11 11 11 0 Chordopoxvirus multifunctional envelope protein A27 HTH_19 PF12844.7 GAN01538.1 - 0.023 14.7 0.1 0.94 9.6 0.0 3.8 4 1 0 4 4 4 0 Helix-turn-helix domain VitD-bind_III PF09164.10 GAN01538.1 - 0.16 12.0 1.7 4.8 7.2 0.1 4.6 6 0 0 6 6 6 0 Vitamin D binding protein, domain III Troponin PF00992.20 GAN01538.1 - 0.42 10.9 0.0 0.42 10.9 0.0 4.4 5 1 0 5 5 4 0 Troponin CMD PF02627.20 GAN01538.1 - 0.79 9.8 3.2 19 5.4 0.2 4.6 4 0 0 4 4 4 0 Carboxymuconolactone decarboxylase family Gln-synt_C PF00120.24 GAN01538.1 - 2.2 7.2 10.2 0.13 11.2 0.1 4.1 4 0 0 4 4 4 0 Glutamine synthetase, catalytic domain DUF489 PF04356.12 GAN01538.1 - 3.1 7.8 8.7 6.3 6.8 2.4 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF489) HAMP PF00672.25 GAN01539.1 - 2.1e-21 76.0 5.4 7.7e-09 35.8 0.1 4.7 3 3 3 6 6 6 3 HAMP domain SpoIIID PF12116.8 GAN01539.1 - 5.1e-05 23.3 2.1 6.7 6.9 0.0 3.9 4 0 0 4 4 4 3 Stage III sporulation protein D Baculo_PEP_C PF04513.12 GAN01539.1 - 0.00021 21.4 8.6 0.15 12.1 0.3 3.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 GAN01539.1 - 0.00021 20.6 0.0 0.19 10.8 0.0 2.1 1 1 1 2 2 2 2 Autophagy protein Apg17 DUF948 PF06103.11 GAN01539.1 - 0.00036 20.7 22.0 2.2 8.6 0.7 4.9 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 GAN01539.1 - 0.0008 19.6 1.8 0.63 10.3 0.1 3.3 3 0 0 3 3 3 1 Proteins of 100 residues with WXG Lgl_C PF08596.10 GAN01539.1 - 0.001 17.8 0.1 0.033 12.9 0.0 2.0 1 1 1 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal DUF3829 PF12889.7 GAN01539.1 - 0.0023 17.4 0.0 1.4 8.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3829) Perilipin PF03036.16 GAN01539.1 - 0.0076 15.3 3.3 0.62 9.0 0.1 2.5 3 0 0 3 3 3 2 Perilipin family HTH_6 PF01418.17 GAN01539.1 - 0.0095 15.9 1.1 23 5.1 0.0 4.2 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family FtsX_ECD PF18075.1 GAN01539.1 - 0.016 15.8 2.2 10 6.8 0.1 2.9 3 0 0 3 3 3 0 FtsX extracellular domain HTH_WhiA PF02650.14 GAN01539.1 - 0.035 14.4 3.9 35 4.8 0.1 3.3 3 0 0 3 3 3 0 WhiA C-terminal HTH domain DltD PF04914.12 GAN01539.1 - 0.055 12.8 0.0 6.9 6.0 0.0 2.3 2 0 0 2 2 2 0 DltD protein T7SS_ESX_EspC PF10824.8 GAN01539.1 - 0.21 12.1 8.6 9.2 6.8 0.4 3.6 3 2 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DASH_Dad2 PF08654.10 GAN01539.1 - 0.32 11.4 10.8 26 5.3 0.4 4.6 3 2 0 3 3 3 0 DASH complex subunit Dad2 DUF1725 PF08333.11 GAN01539.1 - 2.8 7.7 5.6 25 4.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) HAMP PF00672.25 GAN01540.1 - 1.7e-32 111.6 4.9 2e-08 34.4 0.0 5.0 4 0 0 4 4 4 4 HAMP domain HATPase_c PF02518.26 GAN01540.1 - 2.3e-30 105.4 0.2 6.4e-30 103.9 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAN01540.1 - 1.4e-27 96.1 0.2 2.2e-25 89.0 0.1 3.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAN01540.1 - 9.5e-18 64.0 1.6 3.7e-17 62.1 0.5 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain WXG100 PF06013.12 GAN01540.1 - 9.4e-06 25.8 10.3 0.045 14.0 0.0 4.7 4 1 0 4 4 4 2 Proteins of 100 residues with WXG HTH_6 PF01418.17 GAN01540.1 - 0.00033 20.6 0.3 19 5.3 0.0 4.7 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family VHS PF00790.19 GAN01540.1 - 0.004 17.0 0.7 0.019 14.8 0.1 2.4 2 0 0 2 2 2 1 VHS domain Jnk-SapK_ap_N PF09744.9 GAN01540.1 - 0.015 15.6 0.4 0.048 13.9 0.4 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ApoLp-III PF07464.11 GAN01540.1 - 0.021 14.9 19.6 0.026 14.6 2.2 4.2 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF3626 PF12294.8 GAN01540.1 - 0.031 13.3 1.4 0.084 11.9 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3626) DUF1759 PF03564.15 GAN01540.1 - 0.041 13.8 0.7 36 4.2 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.12 GAN01540.1 - 0.044 13.8 26.8 0.27 11.3 6.2 5.3 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4279 PF14106.6 GAN01540.1 - 0.046 13.9 0.1 5.2 7.3 0.0 3.8 4 1 1 5 5 4 0 Domain of unknown function (DUF4279) DUF948 PF06103.11 GAN01540.1 - 0.11 12.8 31.4 6.8 7.0 1.9 7.2 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 GAN01540.1 - 0.11 13.1 9.4 11 6.7 1.0 4.5 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF883) FleQ PF06490.11 GAN01540.1 - 0.12 12.7 0.2 0.54 10.6 0.0 2.3 2 0 0 2 2 1 0 Flagellar regulatory protein FleQ DUF4731 PF15875.5 GAN01540.1 - 0.38 11.0 2.9 16 5.8 0.1 3.5 3 1 1 4 4 3 0 Domain of unknown function (DUF4731) Abhydrolase_8 PF06259.12 GAN01540.1 - 0.77 9.4 12.9 2.5 7.7 0.5 3.6 2 2 2 4 4 4 0 Alpha/beta hydrolase SpoIIID PF12116.8 GAN01540.1 - 0.84 9.8 3.8 40 4.4 0.2 4.6 5 0 0 5 5 4 0 Stage III sporulation protein D Plk4_PB2 PF18409.1 GAN01540.1 - 1.3 9.7 5.1 1.3e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 Polo-like Kinase 4 Polo Box 2 CENP-F_leu_zip PF10473.9 GAN01540.1 - 4.1 7.4 15.3 12 5.9 0.3 4.2 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PMC2NT PF08066.12 GAN01540.1 - 5.8 7.7 9.6 23 5.7 2.1 3.7 3 1 0 3 3 3 0 PMC2NT (NUC016) domain GLE1 PF07817.13 GAN01540.1 - 8 5.6 7.4 6.1 6.0 0.2 3.4 1 1 3 4 4 4 0 GLE1-like protein W2 PF02020.18 GAN01541.1 - 3.7e-21 75.1 4.4 3.7e-21 75.1 4.4 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 GAN01541.1 - 5.3e-12 45.0 15.2 8.9e-06 25.2 2.1 4.5 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAN01541.1 - 1.9e-05 24.3 0.5 1.9e-05 24.3 0.5 3.0 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAN01541.1 - 0.00026 20.0 0.3 0.00049 19.2 0.3 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 GAN01541.1 - 0.0008 17.7 0.3 0.0018 16.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 GAN01541.1 - 0.0072 15.9 0.0 0.018 14.6 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase GAPT PF11770.8 GAN01541.1 - 0.043 13.7 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) NTP_transf_3 PF12804.7 GAN01541.1 - 0.17 12.2 0.0 0.83 10.0 0.0 2.0 2 0 0 2 2 2 0 MobA-like NTP transferase domain TFIIS_C PF01096.18 GAN01542.1 - 4.8e-17 61.5 2.0 4.8e-17 61.5 2.0 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF523 PF04463.12 GAN01542.1 - 1.4e-06 28.4 0.6 1.9e-06 28.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF523) RNA_POL_M_15KD PF02150.16 GAN01542.1 - 1.7e-06 27.8 16.2 0.00057 19.7 4.3 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit GATA PF00320.27 GAN01542.1 - 0.0084 15.7 6.4 0.5 10.0 0.1 3.1 3 1 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN01542.1 - 0.03 13.8 10.6 0.59 9.7 1.7 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding zf-TFIIB PF13453.6 GAN01542.1 - 0.045 13.1 8.3 0.046 13.1 1.2 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger Baculo_LEF5_C PF11792.8 GAN01542.1 - 0.05 13.3 1.5 0.05 13.3 1.5 2.8 3 1 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.7 GAN01542.1 - 0.054 13.5 13.5 58 3.8 13.5 3.0 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 GAN01542.1 - 0.06 13.3 10.3 0.077 13.0 1.9 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-IS66 PF13005.7 GAN01542.1 - 0.079 13.4 12.1 1.6 9.2 0.1 4.0 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DUF35_N PF12172.8 GAN01542.1 - 0.092 12.6 2.7 15 5.5 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) A2L_zn_ribbon PF08792.10 GAN01542.1 - 0.1 12.3 16.2 2.9 7.7 0.9 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain tRNA-synt_1f PF01921.18 GAN01542.1 - 0.11 11.4 0.8 0.14 11.1 0.8 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) zinc_ribbon_2 PF13240.6 GAN01542.1 - 0.14 11.9 18.1 0.47 10.2 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAN01542.1 - 0.16 12.1 14.7 2 8.6 0.0 4.0 3 1 1 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 GAN01542.1 - 0.18 11.3 20.8 0.22 11.0 0.0 3.8 4 0 0 4 4 3 0 zinc-ribbon domain Acetone_carb_G PF08882.11 GAN01542.1 - 0.2 11.8 1.6 5.1 7.3 0.4 2.2 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit zinc_ribbon_9 PF14369.6 GAN01542.1 - 0.45 10.8 9.2 20 5.5 0.1 3.5 4 0 0 4 4 3 0 zinc-ribbon Rpr2 PF04032.16 GAN01542.1 - 0.47 10.8 11.9 10 6.5 10.3 2.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.11 GAN01542.1 - 0.64 10.2 11.9 4 7.7 0.0 3.4 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like ArfGap PF01412.18 GAN01542.1 - 0.74 9.9 8.4 0.54 10.3 5.9 1.8 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Terminase_GpA PF05876.12 GAN01542.1 - 0.93 8.0 6.7 0.1 11.2 3.0 1.4 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Prok-RING_1 PF14446.6 GAN01542.1 - 1.6 8.7 12.2 0.79 9.7 3.2 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 HscB_4_cys PF18256.1 GAN01542.1 - 1.8 8.5 10.7 2.2 8.2 3.2 3.7 3 1 1 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif PADR1 PF08063.12 GAN01542.1 - 1.8 8.4 11.5 6.4 6.6 0.1 3.7 4 0 0 4 4 4 0 PADR1 (NUC008) domain zf-ZPR1 PF03367.13 GAN01542.1 - 4.2 7.2 10.7 0.27 11.1 1.3 2.5 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Nudix_N_2 PF14803.6 GAN01542.1 - 4.5 7.3 15.6 29 4.7 2.5 3.7 2 2 2 4 4 4 0 Nudix N-terminal RecR PF02132.15 GAN01542.1 - 6.4 6.4 11.5 0.33 10.6 1.7 3.1 3 0 0 3 3 3 0 RecR protein zinc_ribbon_15 PF17032.5 GAN01542.1 - 6.9 7.5 15.2 71 4.3 0.1 3.6 2 1 0 2 2 2 0 zinc-ribbon family OrfB_Zn_ribbon PF07282.11 GAN01542.1 - 9.4 6.2 10.9 4.6 7.2 3.6 2.7 2 2 0 2 2 2 0 Putative transposase DNA-binding domain Dynamitin PF04912.14 GAN01543.1 - 3.1e-90 303.3 29.4 3.7e-90 303.1 29.4 1.0 1 0 0 1 1 1 1 Dynamitin DUF1451 PF07295.11 GAN01543.1 - 0.019 15.0 0.8 0.019 15.0 0.8 2.5 2 0 0 2 2 2 0 Zinc-ribbon containing domain IL11 PF07400.11 GAN01543.1 - 2.6 7.7 6.9 0.41 10.3 0.5 2.8 3 0 0 3 3 3 0 Interleukin 11 Spectrin PF00435.21 GAN01543.1 - 4.6 7.8 17.3 7.6 7.1 0.7 5.0 2 2 2 4 4 4 0 Spectrin repeat Osmo_CC PF08946.10 GAN01543.1 - 5.2 7.4 6.3 5.5 7.3 0.1 3.6 4 0 0 4 4 4 0 Osmosensory transporter coiled coil Rotamase PF00639.21 GAN01544.1 - 2.6e-24 86.0 0.0 3.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAN01544.1 - 1.9e-20 73.6 0.0 2.4e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 GAN01544.1 - 3.8e-07 30.1 1.9 3.8e-07 30.1 1.9 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 GAN01544.1 - 0.0027 18.5 0.0 0.0036 18.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain RhoGAP PF00620.27 GAN01545.1 - 2.6e-14 53.3 3.6 3.5e-14 52.9 2.1 1.9 2 0 0 2 2 2 1 RhoGAP domain CSF-1 PF05337.11 GAN01545.1 - 0.011 15.8 0.1 0.045 13.8 0.0 2.1 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) zf-C4H2 PF10146.9 GAN01545.1 - 0.65 10.3 3.4 0.54 10.5 0.4 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein EFP_N PF08207.12 GAN01547.1 - 1e-15 57.5 0.5 2.5e-15 56.2 0.1 1.9 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 GAN01547.1 - 2e-14 53.1 0.6 3.9e-14 52.1 0.6 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 GAN01547.1 - 3e-08 33.6 0.1 7.6e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain tRNA-synt_1b PF00579.25 GAN01548.1 - 1.9e-22 80.0 0.0 1.2e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) CBS PF00571.28 GAN01549.1 - 7.7e-27 93.5 5.6 2.3e-07 31.1 0.0 4.5 4 1 1 5 5 5 4 CBS domain DEAD_assoc PF08494.11 GAN01549.1 - 0.011 15.5 0.8 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 DEAD/H associated DUF188 PF02639.14 GAN01549.1 - 0.1 12.2 1.7 0.48 10.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF43 PF01861.16 GAN01549.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain PB1 PF00564.24 GAN01550.1 - 1.3e-10 41.1 0.2 3.6e-10 39.6 0.2 1.8 1 1 0 1 1 1 1 PB1 domain Fcf1 PF04900.12 GAN01551.1 - 1.5e-24 86.3 0.1 2.9e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GAN01551.1 - 0.048 14.0 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 PIN like domain Ploopntkinase2 PF18747.1 GAN01551.1 - 0.2 10.9 2.2 0.3 10.3 2.2 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 Ribosomal_S9 PF00380.19 GAN01552.1 - 2.8e-43 147.3 0.2 5e-43 146.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Cupin_8 PF13621.6 GAN01553.1 - 1.4e-33 116.7 0.1 2.3e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAN01553.1 - 2.3e-06 27.3 0.2 2.3e-06 27.3 0.2 1.9 3 0 0 3 3 3 1 Cupin superfamily protein Mg296 PF09644.10 GAN01553.1 - 0.02 15.1 0.1 0.93 9.6 0.0 2.4 2 0 0 2 2 2 0 Mg296 protein Rft-1 PF04506.13 GAN01555.1 - 8.5e-152 506.5 31.2 9.8e-152 506.3 31.2 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 GAN01555.1 - 3.8e-10 39.6 33.3 6.2e-10 38.9 20.4 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 GAN01555.1 - 6e-08 32.9 10.8 6e-08 32.9 10.8 3.9 3 1 1 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DUF2178 PF09946.9 GAN01555.1 - 0.0045 17.1 1.4 0.042 14.0 0.2 3.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2178) EamA PF00892.20 GAN01556.1 - 7.2e-11 42.4 18.7 0.00075 19.7 1.8 3.1 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 GAN01556.1 - 6.8e-08 32.0 0.7 1.2e-07 31.2 0.7 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAN01556.1 - 0.00015 21.1 10.0 0.0002 20.7 10.0 1.3 1 1 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 GAN01556.1 - 0.00077 19.1 7.1 0.00077 19.1 7.1 1.7 2 0 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 GAN01556.1 - 0.2 11.0 11.2 1.1 8.6 11.2 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family PrgI PF12666.7 GAN01556.1 - 9 7.1 9.9 1.8 9.3 1.9 3.1 2 1 1 3 3 3 0 PrgI family protein zf-Mss51 PF13824.6 GAN01557.1 - 4.8e-19 68.2 16.2 4.8e-19 68.2 16.2 1.8 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 OrfB_Zn_ribbon PF07282.11 GAN01557.1 - 0.42 10.6 4.5 0.94 9.5 4.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.6 GAN01557.1 - 0.79 9.1 4.5 1.6 8.1 4.5 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger GPI-anchored PF10342.9 GAN01558.1 - 8.4e-07 29.7 0.1 1.5e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAD_kinase PF01513.21 GAN01559.1 - 1.5e-71 241.0 0.0 2.7e-70 236.9 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase PDZ_5 PF17817.1 GAN01560.1 - 0.0013 18.9 0.1 0.0054 17.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain zf-HC5HC2H_2 PF13832.6 GAN01561.1 - 1.5e-12 47.6 15.9 5.9e-08 32.8 2.4 3.4 3 0 0 3 3 3 2 PHD-zinc-finger like domain PHD_2 PF13831.6 GAN01561.1 - 1.3e-11 43.8 1.4 1.3e-11 43.8 1.4 2.1 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 GAN01561.1 - 3.6e-09 36.8 2.9 3.6e-09 36.8 2.9 3.6 2 1 2 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 GAN01561.1 - 3.4e-08 33.3 19.0 5.4e-08 32.6 7.4 2.8 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.11 GAN01561.1 - 0.17 12.2 16.5 0.066 13.5 6.0 3.1 2 1 0 2 2 2 0 RING-like domain SID-1_RNA_chan PF13965.6 GAN01561.1 - 1.8 6.9 6.2 0.059 11.8 0.3 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 GAN01561.1 - 3.4 5.8 35.6 1.5 7.0 26.0 2.2 2 0 0 2 2 2 0 CDC45-like protein FANCL_C PF11793.8 GAN01561.1 - 5.3 7.3 20.8 5.6 7.2 8.2 3.1 2 2 1 3 3 3 0 FANCL C-terminal domain RasGEF PF00617.19 GAN01562.1 - 8.9e-28 97.7 7.1 6e-27 95.0 7.1 2.5 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN01562.1 - 1.4e-13 51.0 0.6 1.4e-13 51.0 0.6 4.1 4 1 0 4 4 4 1 RasGEF N-terminal motif Ribosomal_L23eN PF03939.13 GAN01563.1 - 0.18 12.1 3.6 0.19 12.0 0.3 2.5 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain PhoLip_ATPase_C PF16212.5 GAN01564.1 - 1.5e-73 247.6 32.0 1.5e-73 247.6 32.0 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAN01564.1 - 1.1e-23 82.7 1.6 4.4e-23 80.7 1.6 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAN01564.1 - 1.1e-14 54.2 0.0 2e-13 50.2 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN01564.1 - 7.9e-09 36.1 0.6 8.3e-05 23.0 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAN01564.1 - 6e-06 25.9 0.3 6e-06 25.9 0.3 3.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAN01564.1 - 0.00025 20.9 1.6 0.001 18.9 0.1 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase TGBp3 PF02495.17 GAN01564.1 - 3.7 7.3 6.2 18 5.0 0.1 3.6 3 0 0 3 3 3 0 Triple gene block 3 Transketolase_N PF00456.21 GAN01565.1 - 3.7e-157 522.5 0.0 5e-157 522.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAN01565.1 - 2.6e-42 144.5 0.0 4.8e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAN01565.1 - 2.4e-11 43.6 0.0 7.9e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAN01565.1 - 5.2e-05 22.6 0.0 0.00034 19.9 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 GAN01565.1 - 0.003 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Scm3 PF10384.9 GAN01565.1 - 0.054 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 Terpene_synth PF01397.21 GAN01565.1 - 0.084 12.5 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Glyco_transf_28 PF03033.20 GAN01566.1 - 7.4e-25 87.6 0.0 1.5e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 GAN01566.1 - 2.4e-21 75.7 1.1 5.8e-14 51.9 0.2 3.6 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 GAN01566.1 - 1.1e-07 32.3 1.0 3.5e-07 30.7 0.2 2.4 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 GAN01566.1 - 2.8e-06 26.4 0.0 2.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 GAN01566.1 - 0.15 12.5 2.5 0.18 12.2 0.2 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain SARAF PF06682.12 GAN01566.1 - 0.43 10.2 4.6 1.2 8.7 4.6 1.8 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PMT PF02366.18 GAN01567.1 - 1.4e-80 270.4 23.2 1.4e-80 270.4 23.2 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAN01567.1 - 2.6e-63 213.3 4.2 2.6e-63 213.3 4.2 3.9 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase SNARE PF05739.19 GAN01567.1 - 1.2e-15 57.2 2.6 4.1e-15 55.5 2.6 2.0 1 0 0 1 1 1 1 SNARE domain MIR PF02815.19 GAN01567.1 - 5.9e-13 49.1 1.4 3.1e-12 46.7 1.3 2.1 1 1 1 2 2 2 2 MIR domain Syntaxin PF00804.25 GAN01567.1 - 2.1e-07 30.8 9.1 3.4e-07 30.1 9.1 1.3 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 GAN01567.1 - 0.029 14.7 11.5 0.086 13.2 2.9 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF2116 PF09889.9 GAN01567.1 - 0.083 12.9 1.1 0.41 10.7 1.1 2.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) MCPsignal PF00015.21 GAN01567.1 - 0.59 9.9 8.2 0.3 10.9 0.6 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 GAN01567.1 - 1.8 8.6 8.1 7.4 6.6 0.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MRC1 PF09444.10 GAN01567.1 - 2 9.0 12.2 0.12 12.9 1.7 2.9 2 1 1 3 3 3 0 MRC1-like domain Ribosomal_L31e PF01198.19 GAN01568.1 - 1.2e-37 128.0 3.0 1.5e-37 127.7 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e ERAP1_C PF11838.8 GAN01568.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain RasGAP PF00616.19 GAN01569.1 - 3.5e-47 160.8 4.9 1e-46 159.3 4.9 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAN01569.1 - 6.4e-39 133.2 0.3 6.4e-39 133.2 0.3 3.2 3 1 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 GAN01569.1 - 2e-14 53.7 0.3 6.7e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 GAN01569.1 - 0.094 12.6 6.8 0.2 11.5 0.1 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif Glyco_hydro_8 PF01270.17 GAN01570.1 - 1.4e-20 73.4 0.1 2.6e-20 72.5 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 8 Lipase_3 PF01764.25 GAN01572.1 - 1e-26 93.5 0.0 2.7e-26 92.1 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAN01572.1 - 0.0075 15.8 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 GAN01572.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 GAN01572.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 GAN01572.1 - 0.043 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 GAN01572.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 GAN01572.1 - 0.12 12.0 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ferritin PF00210.24 GAN01572.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain Hydrolase_4 PF12146.8 GAN01572.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MutS_V PF00488.21 GAN01573.1 - 1.4e-76 256.7 0.1 3.6e-76 255.4 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 GAN01573.1 - 1.9e-34 118.3 0.3 4.8e-34 117.0 0.3 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 GAN01573.1 - 3.5e-34 118.7 0.1 3.5e-34 118.7 0.1 2.1 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 GAN01573.1 - 1.3e-14 54.7 0.0 4.5e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAN01573.1 - 2.1e-10 40.8 0.8 6.4e-10 39.3 0.8 1.9 1 0 0 1 1 1 1 MutS family domain IV Leuk-A4-hydro_C PF09127.11 GAN01573.1 - 0.038 14.1 2.4 0.091 12.8 1.4 2.2 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF4437 PF14499.6 GAN01574.1 - 0.016 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Clr2_transil PF16761.5 GAN01575.1 - 1e-06 29.4 1.5 3.9e-06 27.6 1.5 1.9 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 PHC2_SAM_assoc PF16616.5 GAN01575.1 - 0.081 13.7 9.9 0.16 12.8 9.9 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 PAP1 PF08601.10 GAN01575.1 - 0.1 12.3 6.6 0.16 11.6 6.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 R3H PF01424.22 GAN01576.1 - 3.5e-18 65.3 0.3 6.1e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 GAN01576.1 - 1.1e-07 31.8 59.1 1.7e-05 24.8 12.5 15.7 18 1 0 18 18 18 7 NF-X1 type zinc finger SMN PF06003.12 GAN01577.1 - 1e-07 31.5 10.7 0.00039 19.8 3.4 2.1 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) Acetyltransf_10 PF13673.7 GAN01578.1 - 1.9e-08 34.3 0.1 7e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN01578.1 - 4.2e-08 33.4 0.0 6.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN01578.1 - 6.2e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN01578.1 - 2.6e-05 24.1 0.0 7.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAN01578.1 - 2.6e-05 24.3 0.0 6.8e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SAM_Ste50p PF09235.10 GAN01578.1 - 0.05 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Acetyltransf_3 PF13302.7 GAN01578.1 - 0.13 12.9 0.0 0.21 12.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HLH PF00010.26 GAN01579.1 - 3e-17 62.3 2.8 6.9e-17 61.2 2.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.27 GAN01580.1 - 3.3e-69 228.9 1.3 1.3e-21 76.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SQS_PSY PF00494.19 GAN01581.1 - 3.4e-34 118.5 0.0 5.2e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase RIX1 PF08167.12 GAN01582.1 - 2.3e-46 157.9 4.3 2.3e-46 157.9 4.3 3.0 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TENA_THI-4 PF03070.16 GAN01582.1 - 0.082 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 TENA/THI-4/PQQC family PQ-loop PF04193.14 GAN01583.1 - 5.8e-20 70.8 15.8 2.1e-15 56.2 3.1 3.1 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 GAN01583.1 - 1.4e-05 25.9 8.2 0.0021 18.9 3.9 2.7 2 1 0 2 2 2 2 ER lumen protein retaining receptor DUF3341 PF11821.8 GAN01583.1 - 0.069 12.8 0.2 0.2 11.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Pex24p PF06398.11 GAN01583.1 - 0.37 9.7 5.8 4.2 6.3 1.7 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF2407 PF10302.9 GAN01584.1 - 3e-08 34.2 1.8 3.4e-07 30.8 0.0 2.5 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF2500 PF10694.9 GAN01584.1 - 0.31 11.6 2.6 2 9.0 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) Miga PF10265.9 GAN01584.1 - 0.57 9.1 5.5 0.68 8.8 5.5 1.1 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 GAN01584.1 - 1.7 7.4 4.7 1.7 7.3 4.7 1.1 1 0 0 1 1 1 0 Presenilin Myb_DNA-bind_7 PF15963.5 GAN01585.1 - 1.7e-25 88.7 0.9 1.7e-25 88.7 0.9 2.9 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 GAN01585.1 - 1.1e-07 31.9 0.1 3.9e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN01585.1 - 0.0041 17.3 0.0 0.0092 16.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Skp1 PF01466.19 GAN01585.1 - 0.079 13.1 0.2 0.079 13.1 0.2 3.0 4 0 0 4 4 4 0 Skp1 family, dimerisation domain NAD_binding_5 PF07994.12 GAN01588.1 - 3.7e-148 493.2 0.1 4.4e-148 492.9 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAN01588.1 - 1.3e-44 150.9 0.2 2.5e-44 150.0 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase RRM_1 PF00076.22 GAN01589.1 - 7.2e-19 67.4 0.6 1.3e-13 50.6 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1d PF00750.19 GAN01590.1 - 2.1e-92 309.8 1.1 3.1e-92 309.2 1.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAN01590.1 - 3.8e-23 81.9 0.1 1.1e-22 80.4 0.1 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Surp PF01805.20 GAN01590.1 - 1.7e-16 59.9 0.1 5.9e-16 58.2 0.1 2.0 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 GAN01590.1 - 1.3e-15 56.9 0.0 3.4e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 GAN01590.1 - 0.0002 22.1 1.8 0.00028 21.6 0.4 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_5 PF13893.6 GAN01590.1 - 0.0056 16.3 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN01590.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Arg_tRNA_synt_N PF03485.16 GAN01590.1 - 0.022 15.4 0.4 0.071 13.7 0.4 1.9 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain CTK3 PF12243.8 GAN01590.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 rve PF00665.26 GAN01591.1 - 1.4e-11 44.7 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 GAN01591.1 - 0.031 14.0 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Seipin PF06775.14 GAN01592.1 - 4.5e-50 170.5 3.6 6.6e-50 170.0 3.6 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FAD_binding_3 PF01494.19 GAN01593.1 - 1.1e-20 74.2 0.0 9.2e-10 38.3 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAN01593.1 - 0.00086 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN01593.1 - 0.0011 18.3 0.2 0.0041 16.4 0.2 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAN01593.1 - 0.0011 18.1 0.0 0.16 11.0 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 GAN01593.1 - 0.0019 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 GAN01593.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAN01593.1 - 0.023 15.3 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAN01593.1 - 0.03 13.2 0.0 0.12 11.2 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 GAN01593.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GAN01593.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IMS PF00817.20 GAN01594.1 - 2.5e-46 157.4 0.0 6.1e-46 156.1 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 GAN01594.1 - 3e-12 47.3 0.0 8.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAN01594.1 - 2e-05 24.7 0.0 9.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif RNF220 PF15926.5 GAN01594.1 - 2.4e-05 24.1 1.0 4.3e-05 23.3 1.0 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 MazG_C PF18722.1 GAN01594.1 - 0.012 15.1 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 MazG C-terminal domain DUF4542 PF15075.6 GAN01594.1 - 0.11 12.9 1.3 14 6.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4542) SKI PF01202.22 GAN01595.1 - 0.05 13.7 0.0 0.088 12.9 0.0 1.6 1 1 0 1 1 1 0 Shikimate kinase DSPc PF00782.20 GAN01596.1 - 3.6e-22 78.6 0.1 6.3e-20 71.3 0.1 2.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 GAN01596.1 - 2.5e-08 34.4 0.1 2.9e-05 24.5 0.0 2.8 2 1 0 2 2 2 2 Rhodanese-like domain Y_phosphatase PF00102.27 GAN01596.1 - 0.0035 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 GAN01596.1 - 0.011 16.1 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half DUF641 PF04859.12 GAN01597.1 - 0.012 15.9 2.1 0.012 15.9 2.1 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) AIP3 PF03915.13 GAN01597.1 - 0.13 11.3 9.4 0.23 10.5 9.4 1.5 1 1 0 1 1 1 0 Actin interacting protein 3 Ecl1 PF12855.7 GAN01597.1 - 8.6 7.5 26.0 25 6.0 26.0 1.7 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins TPR_2 PF07719.17 GAN01599.1 - 3.1e-10 39.3 0.2 0.00038 20.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN01599.1 - 1.4e-08 34.2 0.1 0.0027 17.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN01599.1 - 2.2e-05 24.3 0.2 0.059 13.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAN01599.1 - 0.00079 19.5 0.1 0.0074 16.4 0.1 2.0 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 GAN01599.1 - 0.012 15.3 0.1 0.51 10.1 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 GAN01599.1 - 0.021 15.6 0.3 12 7.1 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN01599.1 - 0.053 13.8 1.6 14 6.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAN01599.1 - 0.11 13.1 1.9 5.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 GAN01600.1 - 0.021 14.7 0.7 0.021 14.7 0.7 2.5 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 GAN01600.1 - 0.063 13.2 1.6 0.13 12.2 0.1 2.4 3 0 0 3 3 3 0 F-box domain MFS_1 PF07690.16 GAN01601.1 - 4.2e-49 167.4 17.1 4.2e-49 167.4 17.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN01601.1 - 4.2e-13 49.0 3.6 4.2e-13 49.0 3.6 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAN01601.1 - 1.4e-08 33.7 6.9 2.2e-08 33.0 6.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 GAN01601.1 - 6.9e-06 25.2 3.8 0.0023 16.9 1.7 2.4 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_2 PF13347.6 GAN01601.1 - 0.00036 19.2 3.8 0.00036 19.2 3.8 3.0 3 1 1 4 4 4 2 MFS/sugar transport protein OATP PF03137.20 GAN01601.1 - 0.00045 18.7 5.2 0.00045 18.7 5.2 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 GAN01601.1 - 0.005 15.3 2.1 0.0089 14.5 2.1 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 GAN01601.1 - 0.03 13.2 0.1 0.03 13.2 0.1 2.7 2 1 1 3 3 3 0 MFS_1 like family HLH PF00010.26 GAN01602.1 - 1.8e-11 43.8 1.9 2e-11 43.6 0.2 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain CENP-B_dimeris PF09026.10 GAN01602.1 - 0.025 15.0 4.3 0.048 14.0 4.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2 PF00096.26 GAN01603.1 - 2.1e-12 46.8 12.0 4.5e-06 26.8 4.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN01603.1 - 2.9e-07 30.6 16.0 1.1e-05 25.7 2.8 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN01603.1 - 6.7e-07 29.6 14.1 0.0022 18.7 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAN01603.1 - 0.00082 19.6 1.0 0.0015 18.7 1.0 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 GAN01603.1 - 0.66 10.3 8.6 5 7.5 1.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 GAN01603.1 - 3.1 7.8 7.2 15 5.6 1.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 GAN01603.1 - 4.4 7.1 14.0 12 5.7 3.5 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.7 GAN01603.1 - 6.7 7.2 15.8 2.2 8.8 1.7 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type LMBR1 PF04791.16 GAN01604.1 - 1.9e-17 63.4 19.3 2.3e-16 59.8 6.5 2.1 2 0 0 2 2 2 2 LMBR1-like membrane protein Bap31 PF05529.12 GAN01604.1 - 5.9 6.8 8.1 3.4 7.5 4.4 2.5 2 1 1 3 3 3 0 Bap31/Bap29 transmembrane region Mit_ribos_Mrp51 PF11709.8 GAN01605.1 - 3.6e-14 53.1 10.9 9.3e-09 35.3 7.4 4.0 2 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit DUSP PF06337.12 GAN01605.1 - 0.11 13.2 0.1 0.23 12.1 0.1 1.4 1 0 0 1 1 1 0 DUSP domain RNA_pol_Rpb4 PF03874.16 GAN01606.1 - 3.2e-21 75.9 2.4 4.5e-21 75.5 2.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pro-MCH PF05824.12 GAN01606.1 - 0.042 13.8 0.2 0.2 11.6 0.1 2.1 2 1 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) CUE PF02845.16 GAN01607.1 - 5.9e-07 29.1 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 GAN01607.1 - 0.00033 20.5 0.1 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain MlaE PF02405.16 GAN01607.1 - 0.049 13.3 0.6 0.049 13.3 0.6 2.4 2 1 1 3 3 3 0 Permease MlaE Rhomboid PF01694.22 GAN01607.1 - 0.052 13.6 4.7 0.098 12.7 4.7 1.5 1 0 0 1 1 1 0 Rhomboid family DER1 PF04511.15 GAN01607.1 - 0.12 12.3 7.2 0.18 11.7 7.2 1.3 1 0 0 1 1 1 0 Der1-like family FMO-like PF00743.19 GAN01608.1 - 1.9e-16 59.6 0.7 2.3e-14 52.7 0.2 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAN01608.1 - 4.3e-11 42.5 3.2 3.3e-10 39.6 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN01608.1 - 1.6e-09 37.8 0.1 5.1e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN01608.1 - 5.3e-07 29.2 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN01608.1 - 0.00018 21.2 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAN01608.1 - 0.00032 20.1 2.4 0.0049 16.2 1.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN01608.1 - 0.0037 17.3 2.0 1.1 9.2 0.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAN01608.1 - 0.012 14.8 0.1 0.085 12.1 0.1 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 GAN01608.1 - 0.027 13.6 0.2 0.042 12.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAN01608.1 - 0.033 14.8 0.0 1.9 9.1 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAN01608.1 - 0.23 10.5 0.6 2.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-RVT PF13966.6 GAN01609.1 - 0.00048 20.8 1.2 0.001 19.8 1.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HPS3_N PF14761.6 GAN01609.1 - 0.077 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 HSBP1 PF06825.12 GAN01610.1 - 8.6e-05 22.3 0.8 0.005 16.7 0.1 3.9 4 1 1 5 5 5 1 Heat shock factor binding protein 1 T7SS_ESX_EspC PF10824.8 GAN01610.1 - 0.0005 20.5 2.9 0.0014 19.1 0.1 3.0 3 1 1 4 4 4 1 Excreted virulence factor EspC, type VII ESX diderm CsgA PF17334.2 GAN01610.1 - 0.011 16.4 3.0 0.036 14.8 2.3 2.3 2 0 0 2 2 2 0 Minor curli fiber component A Tropomyosin_1 PF12718.7 GAN01610.1 - 0.27 11.4 28.6 0.77 9.9 3.9 3.8 2 1 1 3 3 3 0 Tropomyosin like HALZ PF02183.18 GAN01610.1 - 0.55 10.5 3.7 0.26 11.5 0.6 2.2 2 0 0 2 2 1 0 Homeobox associated leucine zipper DASH_Dad2 PF08654.10 GAN01610.1 - 0.75 10.2 13.8 0.58 10.6 4.8 3.3 2 1 1 3 3 3 0 DASH complex subunit Dad2 DUF4407 PF14362.6 GAN01610.1 - 0.91 8.8 21.5 0.32 10.3 12.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAN01610.1 - 1.1 8.1 26.3 3.8 6.3 4.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 GAN01610.1 - 2.8 8.0 18.5 2.1 8.4 0.9 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAN01610.1 - 3.1 6.2 6.0 2 6.9 3.4 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family COG2 PF06148.11 GAN01610.1 - 3.9 7.6 15.9 3.2 7.9 3.0 3.7 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 NuiA PF07924.11 GAN01611.1 - 2.6e-06 27.9 0.7 1.1e-05 25.8 0.7 1.9 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein 6PGD PF00393.19 GAN01612.1 - 3e-126 420.7 0.0 3.8e-126 420.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAN01612.1 - 2.3e-52 177.3 0.0 3.4e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAN01612.1 - 0.027 14.7 0.1 0.22 11.8 0.0 2.4 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAN01612.1 - 0.036 14.7 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Thioredoxin PF00085.20 GAN01613.1 - 9.1e-43 144.5 3.0 2.6e-26 91.6 0.3 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 GAN01613.1 - 1.9e-20 73.5 1.2 1.5e-15 57.6 0.3 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 GAN01613.1 - 6.8e-08 32.5 0.1 0.0009 19.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_8 PF13905.6 GAN01613.1 - 7.3e-08 32.6 5.3 0.057 13.7 0.1 5.5 4 2 2 6 6 6 2 Thioredoxin-like OST3_OST6 PF04756.13 GAN01613.1 - 1.1e-07 31.5 0.3 0.0085 15.5 0.0 3.3 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 GAN01613.1 - 1.3e-06 27.7 0.4 1.9e-05 23.9 0.3 2.2 2 1 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 GAN01613.1 - 1.9e-06 28.3 0.6 0.0017 18.8 0.1 3.3 3 0 0 3 3 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAN01613.1 - 3.4e-05 23.8 1.9 0.023 14.6 0.1 3.7 4 0 0 4 4 4 1 AhpC/TSA family B2-adapt-app_C PF09066.10 GAN01613.1 - 0.013 15.5 0.0 0.15 12.1 0.0 2.6 3 0 0 3 3 3 0 Beta2-adaptin appendage, C-terminal sub-domain Thioredoxin_9 PF14595.6 GAN01613.1 - 0.02 14.7 0.2 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 GAN01613.1 - 0.24 11.6 1.1 2.4 8.4 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin-like TraF PF13728.6 GAN01613.1 - 0.57 10.0 3.7 12 5.6 0.0 3.4 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 GAN01613.1 - 0.77 9.9 10.4 0.23 11.6 0.2 2.9 3 0 0 3 3 3 0 Thioredoxin Bromo_TP PF07524.13 GAN01614.1 - 5.5e-16 58.3 0.0 1.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 GAN01614.1 - 8.9e-12 44.7 7.4 1.6e-11 43.9 7.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAN01614.1 - 1e-08 34.6 3.4 1.7e-08 33.8 3.4 1.4 1 0 0 1 1 1 1 PHD-finger Bromo_TP_like PF17027.5 GAN01614.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 Histone-fold protein zf-PHD-like PF15446.6 GAN01614.1 - 0.024 14.3 0.6 0.091 12.4 0.6 2.0 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Aldolase_II PF00596.21 GAN01615.1 - 3e-47 160.9 0.0 3.6e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sugar_tr PF00083.24 GAN01616.1 - 3.1e-50 171.4 24.5 4.1e-50 171.0 24.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN01616.1 - 1.6e-25 89.8 37.2 9.2e-24 84.0 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NTPase_I-T PF01931.18 GAN01616.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF84 DUF2198 PF09964.9 GAN01616.1 - 3.2 7.9 6.9 1.3 9.1 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) KH_1 PF00013.29 GAN01618.1 - 1.8e-21 75.8 0.0 7.3e-06 25.7 0.0 6.5 6 0 0 6 6 6 4 KH domain Abp2 PF09441.10 GAN01618.1 - 6.9e-20 71.8 0.1 1.6e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 ARS binding protein 2 GCP_N_terminal PF17681.1 GAN01618.1 - 0.0091 15.6 0.3 0.022 14.4 0.3 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal FlaC_arch PF05377.11 GAN01618.1 - 0.18 12.2 1.3 0.75 10.2 1.3 2.1 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HR1 PF02185.16 GAN01618.1 - 0.52 10.5 5.6 1.3 9.2 1.0 3.0 2 0 0 2 2 2 0 Hr1 repeat DUF4234 PF14018.6 GAN01619.1 - 5.7e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4234) SDF PF00375.18 GAN01619.1 - 0.17 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Tox-SHH PF15652.6 GAN01620.1 - 0.0095 16.9 0.4 0.22 12.5 0.0 2.5 2 0 0 2 2 2 1 HNH/Endo VII superfamily toxin with a SHH signature MOZ_SAS PF01853.18 GAN01621.1 - 3.2e-78 261.5 0.3 4.8e-78 260.9 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAN01621.1 - 1.6e-15 56.4 0.6 1.6e-15 56.4 0.6 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 GAN01621.1 - 0.0011 19.3 0.0 0.0043 17.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3290 PF11694.8 GAN01621.1 - 0.078 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) WD40 PF00400.32 GAN01622.1 - 3.1e-39 132.2 17.7 1.6e-06 28.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN01622.1 - 4.4e-12 46.1 0.0 0.011 16.0 0.1 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN01622.1 - 0.00051 20.0 0.0 2.7 7.8 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN01622.1 - 0.00088 18.3 2.0 28 3.5 0.0 4.6 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAN01622.1 - 0.0036 16.7 0.0 0.031 13.6 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain Nup160 PF11715.8 GAN01622.1 - 0.018 13.7 0.1 4 5.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ribonuc_L-PSP PF01042.21 GAN01623.1 - 2e-47 160.2 1.2 2.2e-47 160.0 1.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sel1 PF08238.12 GAN01624.1 - 3.8e-29 100.5 16.0 9.3e-08 32.5 0.4 6.9 7 0 0 7 7 7 6 Sel1 repeat HTH_28 PF13518.6 GAN01624.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Prp18 PF02840.15 GAN01625.1 - 3.3e-58 195.8 0.1 3.3e-58 195.8 0.1 2.3 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 GAN01625.1 - 2.6e-10 39.7 0.4 6.4e-10 38.4 0.4 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like AvrPphF-ORF-2 PF09143.10 GAN01625.1 - 0.062 13.2 0.1 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 AvrPphF-ORF-2 EIIBC-GUT_N PF03612.14 GAN01625.1 - 1.4 8.6 4.5 3.8 7.2 4.5 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CKS PF01111.19 GAN01626.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit W2 PF02020.18 GAN01627.1 - 7e-12 45.3 4.1 7e-12 45.3 4.1 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon ZapB PF06005.12 GAN01627.1 - 0.019 15.4 0.5 3.3 8.2 0.0 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Csm1_N PF18504.1 GAN01627.1 - 0.021 15.1 0.7 0.22 11.9 0.2 2.9 2 0 0 2 2 2 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 GAN01627.1 - 0.062 14.2 0.3 0.062 14.2 0.3 3.6 4 0 0 4 4 4 0 cGMP-dependent protein kinase interacting domain SR-25 PF10500.9 GAN01627.1 - 1.4 8.4 12.9 0.84 9.2 1.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BORCS7 PF16088.5 GAN01628.1 - 1.9e-20 73.0 5.9 2.3e-20 72.8 5.9 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 DUF948 PF06103.11 GAN01628.1 - 0.075 13.3 1.8 0.11 12.7 1.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CLTH PF10607.9 GAN01629.1 - 1.6e-24 86.5 0.8 3e-24 85.6 0.8 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAN01629.1 - 0.00025 20.9 0.1 0.00045 20.1 0.1 1.4 1 0 0 1 1 1 1 LisH Ribosomal_L38e PF01781.18 GAN01630.1 - 7.9e-36 122.0 3.3 8.6e-36 121.9 3.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family CRF PF00473.17 GAN01630.1 - 0.005 16.9 0.5 0.01 15.9 0.5 1.5 1 0 0 1 1 1 1 Corticotropin-releasing factor family TFIID_NTD2 PF04494.15 GAN01630.1 - 0.039 14.2 0.2 0.046 13.9 0.2 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UCH PF00443.29 GAN01631.1 - 2.9e-40 138.4 0.1 4.8e-40 137.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN01631.1 - 2e-05 24.3 6.0 2e-05 24.3 6.0 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SusD-like_2 PF12771.7 GAN01631.1 - 0.037 13.0 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane MaoC_dehydratas PF01575.19 GAN01632.1 - 3.3e-28 97.7 0.0 6.6e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAN01632.1 - 0.024 14.8 0.0 0.12 12.5 0.0 2.1 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase NDC10_II PF16787.5 GAN01633.1 - 0.0026 16.9 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 ADP_ribosyl_GH PF03747.14 GAN01633.1 - 0.052 13.3 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ilm1 PF10311.9 GAN01633.1 - 0.053 13.2 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 adh_short PF00106.25 GAN01634.1 - 1.1e-55 188.2 0.2 3.6e-55 186.4 0.4 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN01634.1 - 2.8e-42 144.9 0.2 4.1e-42 144.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN01634.1 - 2.2e-14 53.7 0.4 3.6e-14 53.1 0.4 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAN01634.1 - 2.8e-05 23.4 0.3 4.3e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAN01634.1 - 4.8e-05 22.9 0.1 0.00011 21.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAN01634.1 - 0.00065 19.6 1.1 0.0012 18.8 1.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAN01634.1 - 0.017 14.5 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_S8 PF00082.22 GAN01635.1 - 1.9e-34 119.3 5.6 3.5e-34 118.4 5.6 1.4 1 0 0 1 1 1 1 Subtilase family RHH_3 PF12651.7 GAN01635.1 - 0.12 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain SPRY PF00622.28 GAN01636.1 - 2.2e-18 66.5 0.2 3.9e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 GAN01636.1 - 6.3e-10 38.8 2.2 1.6e-09 37.4 2.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN01636.1 - 0.00062 19.6 4.9 0.0016 18.2 4.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN01636.1 - 0.006 16.9 5.4 0.02 15.2 5.4 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAN01636.1 - 0.033 14.1 6.3 0.11 12.4 6.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN01636.1 - 0.49 10.4 7.2 0.25 11.3 4.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain AA_permease_2 PF13520.6 GAN01637.1 - 4.4e-64 216.9 51.9 5.5e-64 216.5 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN01637.1 - 9.6e-27 93.7 42.1 1.4e-26 93.2 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease RAMP4 PF06624.12 GAN01637.1 - 0.11 12.5 1.2 14 5.9 0.6 2.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 ANAPC4_WD40 PF12894.7 GAN01640.1 - 6.9e-05 23.1 0.0 0.00045 20.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Titin_Z PF09042.11 GAN01640.1 - 0.88 9.6 6.1 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 Titin Z Rotamase_3 PF13616.6 GAN01641.1 - 8.7e-19 68.2 0.1 2e-18 67.0 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 GAN01641.1 - 6.9e-17 62.2 0.1 1.5e-16 61.2 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAN01641.1 - 0.0034 18.2 0.0 0.0055 17.5 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain ADP_PFK_GK PF04587.15 GAN01641.1 - 0.062 11.9 0.1 0.069 11.7 0.1 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region PHC2_SAM_assoc PF16616.5 GAN01643.1 - 0.07 13.9 4.8 0.14 13.0 4.8 1.5 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 KMP11 PF03037.16 GAN01643.1 - 0.11 13.3 0.0 0.17 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 KH_7 PF17214.3 GAN01643.1 - 0.12 12.3 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 KH domain IL10 PF00726.17 GAN01643.1 - 0.17 11.4 0.9 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Interleukin 10 Orthopox_A5L PF06193.11 GAN01643.1 - 0.58 9.6 8.0 0.93 8.9 8.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like SUR7 PF06687.12 GAN01644.1 - 3.4e-06 26.8 15.0 2.9e-05 23.8 0.3 2.3 1 1 1 2 2 2 2 SUR7/PalI family DUF2721 PF11026.8 GAN01644.1 - 8.1 6.4 7.8 16 5.4 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Cyclin PF08613.11 GAN01645.1 - 1.5e-40 139.2 1.5 1.5e-40 139.2 1.5 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAN01645.1 - 3e-06 27.0 0.1 5.8e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DER1 PF04511.15 GAN01645.1 - 0.076 12.9 1.9 0.098 12.6 1.9 1.2 1 0 0 1 1 1 0 Der1-like family RE_NgoFVII PF09565.10 GAN01645.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease MT-A70 PF05063.14 GAN01646.1 - 3.3e-38 131.3 0.0 4.6e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.15 GAN01646.1 - 0.019 14.6 0.0 0.054 13.1 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Atu4866 PF11512.8 GAN01646.1 - 0.098 13.1 0.2 7.4 7.0 0.0 2.7 2 1 1 3 3 3 0 Agrobacterium tumefaciens protein Atu4866 TolA_bind_tri PF16331.5 GAN01646.1 - 0.25 11.4 2.1 0.54 10.4 2.1 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation FlxA PF14282.6 GAN01646.1 - 0.26 11.3 4.0 0.51 10.3 4.0 1.4 1 0 0 1 1 1 0 FlxA-like protein EphA2_TM PF14575.6 GAN01648.1 - 0.032 15.1 0.1 0.048 14.5 0.1 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Nebulin PF00880.18 GAN01648.1 - 0.064 13.2 1.9 1.2 9.1 0.5 2.3 2 0 0 2 2 2 0 Nebulin repeat DUF4834 PF16118.5 GAN01648.1 - 0.12 13.3 1.7 0.19 12.7 1.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 GAN01648.1 - 0.14 12.0 1.3 0.33 10.8 1.3 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Ost5 PF05251.12 GAN01649.1 - 9.6e-17 61.0 6.1 1.1e-16 60.9 6.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 TOM13 PF08219.11 GAN01650.1 - 3.4e-20 71.8 0.3 3.4e-20 71.8 0.3 1.5 2 0 0 2 2 2 1 Outer membrane protein TOM13 SepSecS PF05889.13 GAN01650.1 - 0.025 13.3 0.0 0.026 13.2 0.0 1.0 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS UDPGT PF00201.18 GAN01651.1 - 2.2e-19 69.6 0.0 2.8e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN01651.1 - 3.4e-05 23.9 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Tropomyosin_1 PF12718.7 GAN01652.1 - 1.6e-17 64.0 20.4 1.2e-10 41.7 7.6 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 GAN01652.1 - 1.4e-05 24.6 22.4 1.6e-05 24.4 22.4 1.0 1 0 0 1 1 1 1 Tropomyosin DUF3450 PF11932.8 GAN01652.1 - 0.0028 17.0 16.8 0.072 12.4 4.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Tup_N PF08581.10 GAN01652.1 - 0.003 17.8 12.3 0.064 13.6 6.0 2.2 1 1 1 2 2 2 2 Tup N-terminal WXG100 PF06013.12 GAN01652.1 - 0.0056 16.9 9.8 0.15 12.3 1.3 3.0 2 1 1 3 3 3 2 Proteins of 100 residues with WXG Atg14 PF10186.9 GAN01652.1 - 0.0079 15.3 8.2 0.0079 15.3 8.2 1.9 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 TolA_bind_tri PF16331.5 GAN01652.1 - 0.0079 16.2 6.5 0.071 13.2 0.1 2.7 2 1 0 2 2 2 1 TolA binding protein trimerisation GAS PF13851.6 GAN01652.1 - 0.02 14.3 18.2 0.49 9.7 1.7 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FliD_C PF07195.12 GAN01652.1 - 0.028 13.8 5.5 0.26 10.7 0.8 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Fez1 PF06818.15 GAN01652.1 - 0.037 14.5 14.7 0.019 15.4 12.7 1.5 1 1 0 1 1 1 0 Fez1 DUF4201 PF13870.6 GAN01652.1 - 0.046 13.5 15.2 0.17 11.6 10.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 GAN01652.1 - 0.05 13.8 21.1 0.35 11.1 18.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAN01652.1 - 0.06 12.2 21.3 0.15 11.0 19.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.12 GAN01652.1 - 0.067 11.4 13.9 0.077 11.2 13.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 GAN01652.1 - 0.079 13.0 22.6 0.27 11.3 3.9 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 GAN01652.1 - 0.12 12.5 4.6 0.49 10.4 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 GAN01652.1 - 0.16 11.6 20.8 1.2 8.8 20.8 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 GAN01652.1 - 0.2 11.9 20.0 0.27 11.5 20.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 GAN01652.1 - 0.21 11.9 9.6 0.36 11.1 9.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Laminin_II PF06009.12 GAN01652.1 - 0.25 11.3 7.6 0.39 10.7 7.6 1.4 1 1 0 1 1 1 0 Laminin Domain II Uso1_p115_C PF04871.13 GAN01652.1 - 0.28 11.5 25.6 0.35 11.2 18.3 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 GAN01652.1 - 0.31 11.1 17.9 1.9 8.6 3.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 GAN01652.1 - 0.34 11.2 10.1 0.068 13.4 2.0 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4472 PF14739.6 GAN01652.1 - 0.35 11.6 16.9 0.35 11.6 11.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Nup54 PF13874.6 GAN01652.1 - 0.49 10.5 12.6 0.29 11.2 8.3 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF16 PF01519.16 GAN01652.1 - 0.53 10.8 10.1 6.4 7.3 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Occludin_ELL PF07303.13 GAN01652.1 - 0.56 11.0 7.7 1.1 10.0 5.0 2.4 1 1 1 2 2 2 0 Occludin homology domain Cdh1_DBD_1 PF18196.1 GAN01652.1 - 0.59 10.5 12.4 0.074 13.4 7.2 2.0 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Nsp1_C PF05064.13 GAN01652.1 - 0.74 9.6 11.7 0.64 9.8 4.9 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF724 PF05266.14 GAN01652.1 - 0.74 9.6 17.6 0.67 9.7 8.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 GAN01652.1 - 0.77 7.2 17.8 0.96 6.9 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 GAN01652.1 - 0.84 9.7 25.3 0.37 10.9 17.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 GAN01652.1 - 0.89 9.6 24.5 3.2 7.8 15.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 GAN01652.1 - 1.1 8.1 18.8 1.7 7.4 18.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 GAN01652.1 - 1.2 9.7 30.1 3 8.4 18.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region GrpE PF01025.19 GAN01652.1 - 1.3 8.7 21.7 0.38 10.4 3.3 2.3 1 1 1 2 2 2 0 GrpE BRE1 PF08647.11 GAN01652.1 - 1.5 9.0 20.9 1.5 8.9 5.6 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ERM PF00769.19 GAN01652.1 - 1.5 8.5 27.6 5.1 6.8 27.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Troponin PF00992.20 GAN01652.1 - 1.8 8.9 21.1 5.1 7.4 7.3 2.1 1 1 1 2 2 2 0 Troponin PI3K_P85_iSH2 PF16454.5 GAN01652.1 - 1.9 8.1 14.9 2.1 7.9 1.0 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain THOC7 PF05615.13 GAN01652.1 - 1.9 8.8 19.9 0.51 10.6 2.6 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 V_ATPase_I PF01496.19 GAN01652.1 - 2 6.2 9.0 2.1 6.2 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 GAN01652.1 - 2.3 7.5 15.4 3.7 6.8 15.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GAN01652.1 - 2.8 7.4 9.0 3.1 7.3 9.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 GAN01652.1 - 3.1 7.1 10.2 3.7 6.8 10.2 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4200 PF13863.6 GAN01652.1 - 3.8 7.9 23.4 23 5.4 23.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.9 GAN01652.1 - 4.2 7.6 15.4 11 6.2 15.4 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein UPF0242 PF06785.11 GAN01652.1 - 4.6 7.3 19.7 9.8 6.2 12.9 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 GAN01652.1 - 4.9 7.4 20.5 6.3 7.1 10.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 GAN01652.1 - 5.9 6.7 19.6 0.34 10.7 2.1 3.0 1 1 1 3 3 3 0 Septum formation initiator Lectin_N PF03954.14 GAN01652.1 - 6 6.6 6.6 4.5 7.0 3.9 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF2203 PF09969.9 GAN01652.1 - 6.2 7.6 12.2 1.2 9.9 5.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) 5_nucleotid PF05761.14 GAN01652.1 - 6.2 5.6 7.4 7.8 5.3 7.4 1.3 1 0 0 1 1 1 0 5' nucleotidase family Spc24 PF08286.11 GAN01652.1 - 6.3 7.1 16.6 2.2e+03 -1.1 16.6 2.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 GAN01652.1 - 8 6.5 20.1 30 4.6 4.9 3.1 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 GAN01652.1 - 8.5 6.9 10.0 22 5.5 2.3 3.6 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) KELK PF15796.5 GAN01652.1 - 8.7 6.9 19.1 1.7 9.1 11.6 2.5 1 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GST_N_2 PF13409.6 GAN01653.1 - 3.4e-21 75.3 0.1 1.7e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAN01653.1 - 1.6e-11 44.0 0.0 4.9e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN01653.1 - 3.9e-07 30.2 0.0 1.1e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAN01653.1 - 1.4e-06 28.4 0.1 4.6e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAN01653.1 - 0.0059 17.0 0.2 0.13 12.7 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAN01653.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RGI1 PF10843.8 GAN01653.1 - 0.024 14.3 0.5 0.05 13.3 0.5 1.5 1 0 0 1 1 1 0 Respiratory growth induced protein 1 Fasciclin PF02469.22 GAN01654.1 - 5.4e-76 253.0 0.0 7.8e-19 68.2 0.0 5.2 5 0 0 5 5 5 5 Fasciclin domain Hexapep PF00132.24 GAN01654.1 - 0.076 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) F-box PF00646.33 GAN01655.1 - 1.7e-07 30.9 0.5 4.4e-07 29.6 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN01655.1 - 2.6e-07 30.4 0.3 8.6e-07 28.8 0.3 1.9 1 0 0 1 1 1 1 F-box-like DUF21 PF01595.20 GAN01656.1 - 1.3e-31 109.6 3.8 1.3e-31 109.6 3.8 2.3 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Sec34 PF04136.15 GAN01657.1 - 2.3e-48 163.8 1.2 2.3e-48 163.8 1.2 2.8 4 0 0 4 4 4 1 Sec34-like family Pil1 PF13805.6 GAN01659.1 - 9.2e-41 140.1 4.7 1.6e-40 139.3 4.7 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 V_ATPase_I PF01496.19 GAN01660.1 - 0 1059.1 11.2 0 1058.7 11.2 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family KLRAQ PF10205.9 GAN01660.1 - 0.0029 17.8 1.4 0.0087 16.3 1.4 1.8 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Tmemb_cc2 PF10267.9 GAN01660.1 - 0.021 14.0 5.3 0.037 13.2 5.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CCDC85 PF10226.9 GAN01660.1 - 0.024 14.3 0.6 0.051 13.3 0.6 1.6 1 0 0 1 1 1 0 CCDC85 family BLOC1_2 PF10046.9 GAN01660.1 - 0.48 10.7 3.6 2.1 8.7 0.7 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BAR PF03114.18 GAN01661.1 - 5.4e-31 108.1 9.8 7.4e-31 107.6 9.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 GAN01661.1 - 8.5e-15 54.4 0.2 1.4e-14 53.7 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN01661.1 - 2e-14 52.9 0.2 3.5e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN01661.1 - 5.3e-08 32.4 0.1 1e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 GAN01661.1 - 1.8e-07 30.6 5.6 2.5e-07 30.2 5.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.13 GAN01661.1 - 0.14 11.7 5.9 0.27 10.7 5.9 1.4 1 0 0 1 1 1 0 Arfaptin-like domain DUF3896 PF13035.6 GAN01661.1 - 0.6 10.3 3.6 1.2 9.3 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) CENP-K PF11802.8 GAN01662.1 - 0.028 14.0 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Pkinase PF00069.25 GAN01663.1 - 2.1e-11 43.7 0.0 5.8e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Abhydrolase_6 PF12697.7 GAN01664.1 - 6.5e-08 33.5 0.0 8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN01664.1 - 5.5e-07 29.1 0.0 7.5e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 GAN01664.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) zf-HIT PF04438.16 GAN01665.1 - 3.6e-11 42.7 11.5 5.5e-11 42.1 11.5 1.3 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 GAN01665.1 - 0.095 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 GAN01665.1 - 1.5 9.0 12.2 3.3 7.9 12.2 1.6 1 0 0 1 1 1 0 MYND finger zf-C3HC4_3 PF13920.6 GAN01665.1 - 3.6 7.5 9.5 6.5 6.7 9.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_23 PF13476.6 GAN01665.1 - 4.3 7.8 10.2 5.2 7.5 2.9 2.2 2 0 0 2 2 2 0 AAA domain PseudoU_synth_1 PF01416.20 GAN01666.1 - 8.6e-14 51.9 0.0 1.3e-11 44.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase adh_short_C2 PF13561.6 GAN01667.1 - 1.8e-54 184.8 4.7 2.1e-54 184.6 4.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN01667.1 - 7.2e-46 156.1 1.4 9.6e-46 155.7 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN01667.1 - 1.6e-07 31.4 0.5 5.4e-07 29.7 0.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN01667.1 - 0.00065 19.2 0.1 0.0009 18.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NVEALA PF14055.6 GAN01667.1 - 0.01 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 NVEALA protein Sacchrp_dh_NADP PF03435.18 GAN01667.1 - 0.024 14.9 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Phage_fiber_2 PF03406.13 GAN01667.1 - 0.11 12.0 0.2 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 Phage tail fibre repeat DUF676 PF05057.14 GAN01668.1 - 2.7e-39 135.0 0.0 4.5e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAN01668.1 - 1.3e-06 28.5 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF726 PF05277.12 GAN01668.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 GAN01668.1 - 0.05 14.2 0.0 0.077 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 GAN01668.1 - 0.082 12.5 0.1 0.84 9.1 0.1 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAN01668.1 - 0.092 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 GAN01668.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pex24p PF06398.11 GAN01668.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PGAP1 PF07819.13 GAN01668.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein C2 PF00168.30 GAN01669.1 - 6.7e-25 87.4 0.1 7.9e-25 87.1 0.1 1.1 1 0 0 1 1 1 1 C2 domain CagD PF16567.5 GAN01669.1 - 0.014 15.2 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Pathogenicity island component CagD Glyco_transf_21 PF13506.6 GAN01670.1 - 1.2e-43 148.6 0.0 1.7e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 GAN01670.1 - 5.3e-22 78.8 0.0 7.9e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN01670.1 - 5.3e-15 55.9 1.1 5.3e-15 55.9 1.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAN01670.1 - 0.00032 20.6 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 FHA PF00498.26 GAN01671.1 - 0.00022 21.5 0.5 0.00042 20.6 0.2 1.6 2 0 0 2 2 2 1 FHA domain FHA_2 PF17913.1 GAN01671.1 - 0.0031 17.7 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 FHA domain MAM33 PF02330.16 GAN01672.1 - 2e-62 210.9 10.8 2.4e-62 210.6 10.8 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3658 PF12395.8 GAN01673.1 - 0.014 15.3 0.3 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF5051 PF16473.5 GAN01673.1 - 0.015 15.3 0.3 0.051 13.6 0.1 1.8 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like TMEM208_SND2 PF05620.11 GAN01673.1 - 0.022 14.6 0.2 0.058 13.2 0.2 1.7 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Uds1 PF15456.6 GAN01673.1 - 0.041 14.1 3.3 0.33 11.1 1.5 2.3 2 0 0 2 2 2 0 Up-regulated During Septation DUF5320 PF17253.2 GAN01673.1 - 0.055 14.5 1.4 2.1 9.5 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Prefoldin_2 PF01920.20 GAN01673.1 - 0.087 12.8 14.7 4.1 7.4 0.2 3.2 2 1 1 3 3 3 0 Prefoldin subunit Spore_III_AF PF09581.10 GAN01673.1 - 0.11 12.6 1.2 4.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Cyt_c_ox_IV PF12270.8 GAN01673.1 - 0.15 12.2 1.6 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Tropomyosin_1 PF12718.7 GAN01673.1 - 0.72 10.0 11.9 0.19 11.9 2.7 2.3 2 0 0 2 2 2 0 Tropomyosin like EOS1 PF12326.8 GAN01673.1 - 1.5 8.7 5.0 5.8 6.8 5.0 2.0 1 1 0 1 1 1 0 N-glycosylation protein DivIC PF04977.15 GAN01673.1 - 1.8 8.4 4.5 10 6.0 0.6 2.5 2 1 0 2 2 2 0 Septum formation initiator tRNA-synt_1d PF00750.19 GAN01675.1 - 8.6e-107 357.1 6.9 1.4e-106 356.4 6.9 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAN01675.1 - 8.2e-21 74.4 0.4 5.5e-20 71.7 0.0 2.6 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAN01675.1 - 7.2e-08 32.9 0.0 2.3e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C_2 PF13410.6 GAN01675.1 - 0.00019 21.4 0.3 0.00084 19.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 GAN01676.1 - 2.4e-37 126.6 0.0 2.4e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN01676.1 - 0.002 18.1 0.0 3.2 7.9 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif Velvet PF11754.8 GAN01677.1 - 4.9e-44 151.1 10.9 6.4e-33 114.7 0.6 2.8 2 1 1 3 3 3 2 Velvet factor Endonuclease_NS PF01223.23 GAN01678.1 - 1.6e-56 191.7 0.0 2e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2408 PF10303.9 GAN01679.1 - 0.0014 19.2 4.0 0.0029 18.1 4.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) COG2 PF06148.11 GAN01679.1 - 0.032 14.3 1.1 0.56 10.3 0.2 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SLATT_6 PF18169.1 GAN01679.1 - 0.12 12.0 1.3 0.2 11.2 0.6 1.6 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 MutS_III PF05192.18 GAN01679.1 - 0.22 11.8 2.1 0.26 11.5 2.1 1.1 1 0 0 1 1 1 0 MutS domain III YojJ PF10372.9 GAN01679.1 - 0.3 11.2 3.5 4.8 7.4 1.1 2.6 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Wbp11 PF09429.10 GAN01679.1 - 2 8.8 6.7 4 7.9 2.1 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 tRNA-synt_2b PF00587.25 GAN01680.1 - 1.2e-36 126.3 0.0 2.1e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAN01680.1 - 1.3e-22 80.0 6.0 1.3e-22 80.0 6.0 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 GAN01681.1 - 0.1 13.2 1.3 0.45 11.2 0.2 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Mob_Pre PF01076.19 GAN01681.1 - 0.42 10.4 4.9 1.2 8.9 2.9 2.1 1 1 1 2 2 2 0 Plasmid recombination enzyme Aldedh PF00171.22 GAN01682.1 - 3e-181 603.0 0.0 3.7e-181 602.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAN01682.1 - 0.012 15.0 0.3 0.86 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Raco_middle PF17651.1 GAN01682.1 - 0.061 13.0 0.1 0.18 11.5 0.1 1.8 1 0 0 1 1 1 0 RACo middle region Ank_5 PF13857.6 GAN01683.1 - 1.1e-34 118.0 2.7 1.1e-09 38.4 0.0 6.0 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN01683.1 - 4.6e-31 107.2 1.4 2.4e-10 40.8 0.1 5.6 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN01683.1 - 3e-28 97.8 4.6 4e-06 27.3 0.0 7.7 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 GAN01683.1 - 4e-21 74.4 15.1 0.00019 21.7 0.0 8.0 7 2 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 GAN01683.1 - 1.5e-19 68.0 3.7 0.011 16.2 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat Phage_ABA_S PF18066.1 GAN01683.1 - 0.053 14.2 0.5 0.29 11.8 0.5 2.3 1 0 0 1 1 1 0 Phage ABA sandwich domain T7SS_ESX_EspC PF10824.8 GAN01683.1 - 0.54 10.8 0.0 0.54 10.8 0.0 3.8 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm DUF2939 PF11159.8 GAN01683.1 - 7.7 7.0 6.4 74 3.8 2.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Ras PF00071.22 GAN01684.1 - 9.9e-55 184.6 0.0 1.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN01684.1 - 1.2e-21 77.2 0.0 1.9e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN01684.1 - 1.3e-07 31.2 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAN01684.1 - 0.0038 16.7 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit mRNA_triPase PF02940.15 GAN01685.1 - 6.1e-54 183.1 4.9 7.9e-54 182.7 4.9 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain LIFR_D2 PF17971.1 GAN01685.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor D2 domain PP2C PF00481.21 GAN01686.1 - 1.5e-76 257.4 0.0 2.5e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAN01686.1 - 0.0034 17.1 1.4 0.014 15.1 0.1 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 GAN01686.1 - 0.012 15.5 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Glycos_transf_4 PF00953.21 GAN01687.1 - 1.1e-31 110.0 13.7 1.1e-31 110.0 13.7 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 4 Dpy-30 PF05186.13 GAN01687.1 - 9.7e-15 54.0 0.1 4.4e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Dpy-30 motif His_Phos_2 PF00328.22 GAN01689.1 - 7.7e-33 114.4 0.3 9.9e-33 114.0 0.3 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 GAN01690.1 - 1.2e-29 103.2 0.0 3e-29 101.9 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN01690.1 - 1e-16 61.2 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN01690.1 - 7.2e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN01690.1 - 0.028 13.9 0.1 0.072 12.5 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4718 PF15842.5 GAN01691.1 - 0.056 13.2 1.0 0.14 11.9 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) FAM176 PF14851.6 GAN01691.1 - 0.66 9.6 4.1 3.1 7.5 0.4 2.5 2 0 0 2 2 2 0 FAM176 family RCC1 PF00415.18 GAN01692.1 - 1.9e-44 150.0 16.1 7.5e-10 39.3 0.1 9.3 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAN01692.1 - 4.3e-37 125.2 35.8 4.2e-09 36.0 5.6 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat ApbA PF02558.16 GAN01692.1 - 5.4e-34 117.0 0.0 1.2e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAN01692.1 - 4.5e-29 101.2 0.5 7.8e-29 100.4 0.5 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal HSF_DNA-bind PF00447.17 GAN01694.1 - 1.8e-29 102.2 3.8 1.8e-29 102.2 3.8 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 GAN01694.1 - 1.8e-25 89.3 0.3 5.2e-25 87.8 0.3 1.9 1 0 0 1 1 1 1 Response regulator receiver domain DUF5082 PF16888.5 GAN01694.1 - 0.0014 18.9 7.4 0.0036 17.6 7.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) TcdA_TcdB PF12919.7 GAN01694.1 - 0.02 14.2 6.5 0.036 13.4 6.5 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DivIC PF04977.15 GAN01694.1 - 0.048 13.4 3.5 0.1 12.4 2.0 2.3 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 GAN01694.1 - 0.42 10.9 11.0 0.13 12.5 6.0 2.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4763 PF15960.5 GAN01694.1 - 0.84 8.9 21.2 0.56 9.5 2.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) Baculo_PEP_C PF04513.12 GAN01694.1 - 0.88 9.6 6.0 37 4.3 5.0 2.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 GAN01694.1 - 1.4 8.7 7.6 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ALMT PF11744.8 GAN01694.1 - 2.6 6.8 11.4 0.47 9.2 5.3 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Peroxin-13_N PF04088.13 GAN01695.1 - 8.4e-54 181.8 0.1 1.1e-53 181.4 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 GAN01695.1 - 5.6e-12 45.2 0.0 1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN01695.1 - 1.6e-10 40.4 0.0 3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN01695.1 - 1.6e-08 34.2 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DNApol_Exo PF18136.1 GAN01696.1 - 8.5e-93 310.6 0.1 1.2e-92 310.0 0.1 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 GAN01696.1 - 1.2e-47 162.8 0.0 1.7e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 GAN01696.1 - 0.0056 16.4 0.3 0.029 14.1 0.3 2.2 1 1 0 1 1 1 1 3'-5' exonuclease bPH_3 PF14470.6 GAN01697.1 - 0.098 13.0 1.6 0.26 11.7 1.6 1.8 1 1 0 1 1 1 0 Bacterial PH domain dCMP_cyt_deam_1 PF00383.23 GAN01698.1 - 2.8e-16 59.2 0.0 3.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 GAN01698.1 - 5e-11 42.9 0.3 7.2e-11 42.4 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 GAN01698.1 - 0.089 12.4 0.1 4.3 6.9 0.0 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases DnaJ PF00226.31 GAN01699.1 - 1.8e-18 66.4 4.2 2.2e-18 66.1 3.4 1.6 2 0 0 2 2 2 1 DnaJ domain Gly-zipper_YMGG PF13441.6 GAN01699.1 - 4.6e-05 23.1 2.8 7.9e-05 22.3 2.8 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 GAN01699.1 - 0.0012 18.6 3.5 0.0019 17.9 3.5 1.3 1 0 0 1 1 1 1 Glycine-zipper domain DUF456 PF04306.13 GAN01699.1 - 0.0016 18.7 0.4 0.0023 18.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 GAN01699.1 - 0.0041 17.1 4.8 0.0084 16.1 4.8 1.5 1 0 0 1 1 1 1 Glycine zipper Bacteriocin_IIc PF10439.9 GAN01699.1 - 0.015 15.4 5.1 0.03 14.4 5.1 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.12 GAN01699.1 - 0.091 13.1 1.1 0.19 12.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 GAN01699.1 - 6.3 6.8 8.3 25 4.8 8.4 1.8 1 1 0 1 1 1 0 Glycine zipper 2TM domain RRM_1 PF00076.22 GAN01701.1 - 2.5e-34 116.9 0.0 6.4e-20 70.7 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 GAN01701.1 - 0.0004 20.0 0.4 0.046 13.4 0.2 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.8 GAN01701.1 - 0.00077 19.5 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 RRM_7 PF16367.5 GAN01701.1 - 0.001 19.1 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 GAN01701.1 - 0.028 14.0 0.0 0.62 9.7 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 GAN01701.1 - 0.03 14.5 0.0 8.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SNF2_N PF00176.23 GAN01702.1 - 1.1e-72 244.7 4.1 7e-65 219.0 0.3 3.3 2 1 1 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN01702.1 - 7e-20 71.4 0.1 3.8e-19 69.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN01702.1 - 0.0003 20.8 2.1 0.00034 20.7 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IF-2B PF01008.17 GAN01702.1 - 0.06 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family A2L_zn_ribbon PF08792.10 GAN01702.1 - 0.061 13.1 0.8 0.14 11.9 0.8 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain RNA_pol_3_Rpc31 PF11705.8 GAN01702.1 - 5 7.3 20.4 0.68 10.1 4.1 4.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Cation_ATPase_C PF00689.21 GAN01703.1 - 1e-45 155.7 10.6 1e-45 155.7 10.6 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAN01703.1 - 6.6e-35 120.3 0.4 6.6e-35 120.3 0.4 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAN01703.1 - 1.2e-20 73.3 0.5 2.6e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN01703.1 - 2.9e-16 60.4 0.4 1.7e-15 57.9 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN01703.1 - 2.1e-11 43.4 0.1 2.2e-09 36.9 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN01703.1 - 9.5e-05 22.3 2.1 0.0023 17.7 0.2 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Neugrin PF06413.11 GAN01703.1 - 0.0093 16.0 1.6 0.024 14.7 1.6 1.7 1 0 0 1 1 1 1 Neugrin DDE_Tnp_4 PF13359.6 GAN01705.1 - 2.7e-20 72.6 0.0 7.4e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease ANAPC8 PF04049.13 GAN01705.1 - 0.002 18.2 0.1 0.0036 17.4 0.1 1.4 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 DDE_Tnp_1 PF01609.21 GAN01705.1 - 0.032 13.9 0.1 0.61 9.7 0.0 2.7 2 1 0 2 2 2 0 Transposase DDE domain Tim44 PF04280.15 GAN01706.1 - 6e-23 81.6 0.1 7.9e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 GAN01706.1 - 5.5e-11 42.0 0.2 6.8e-11 41.7 0.2 1.1 1 0 0 1 1 1 1 MBA1-like protein DUF4393 PF14337.6 GAN01706.1 - 0.074 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) GCFC PF07842.12 GAN01707.1 - 3.8e-12 46.4 1.6 4.3e-11 43.0 1.6 2.7 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein DUF3220 PF11516.8 GAN01707.1 - 0.05 13.8 0.0 1.5 9.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3120) GRAS PF03514.14 GAN01707.1 - 1.4 7.8 14.0 0.06 12.3 0.4 3.2 3 0 0 3 3 3 0 GRAS domain family Baculo_PEP_C PF04513.12 GAN01707.1 - 3 7.9 10.1 2.4 8.2 3.6 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 GAN01707.1 - 3.7 7.6 9.5 0.85 9.7 0.2 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Rpp20 PF12328.8 GAN01708.1 - 4.9e-11 42.8 2.0 4.4e-08 33.2 2.0 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 GAN01708.1 - 2.8e-06 27.1 0.9 4.7e-06 26.3 0.9 1.4 1 1 0 1 1 1 1 Alba Ribosomal_S3_C PF00189.20 GAN01709.1 - 1.9e-22 79.6 1.4 6.1e-22 77.9 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAN01709.1 - 1.4e-12 47.2 0.1 2.5e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GAN01709.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UPF0449 PF15136.6 GAN01710.1 - 0.0094 16.4 1.5 0.011 16.2 1.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 ZapB PF06005.12 GAN01710.1 - 0.017 15.6 10.1 0.022 15.2 10.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 GAN01710.1 - 0.091 12.5 5.5 0.11 12.2 5.5 1.2 1 0 0 1 1 1 0 Septum formation initiator LURAP PF14854.6 GAN01710.1 - 0.16 11.9 1.4 0.18 11.8 1.4 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF1664 PF07889.12 GAN01710.1 - 0.28 11.2 3.2 0.32 11.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ribosomal_S3Ae PF01015.18 GAN01711.1 - 1.5e-10 41.0 0.1 1.8e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family PGAP1 PF07819.13 GAN01712.1 - 3.8e-79 265.7 0.1 5.9e-79 265.0 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAN01712.1 - 3.2e-05 23.5 0.0 6.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAN01712.1 - 0.00018 21.5 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 GAN01712.1 - 0.00041 21.0 0.1 0.00096 19.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN01712.1 - 0.0011 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN01712.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 GAN01712.1 - 0.0017 17.6 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 GAN01712.1 - 0.028 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 GAN01712.1 - 0.037 13.6 0.8 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase ABC_tran PF00005.27 GAN01713.1 - 2.4e-49 167.4 0.0 7.1e-26 91.4 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAN01713.1 - 2.4e-17 63.7 0.3 0.00031 20.7 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN01713.1 - 2.2e-13 50.2 5.0 0.0081 15.6 0.0 4.6 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAN01713.1 - 2.4e-08 33.6 0.2 0.0046 16.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAN01713.1 - 3e-08 34.4 3.3 0.0017 18.9 0.0 3.3 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAN01713.1 - 5e-08 33.0 0.9 0.021 14.7 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 GAN01713.1 - 1e-07 32.0 0.0 0.049 13.7 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase Chromo PF00385.24 GAN01713.1 - 2.6e-07 30.4 0.5 5.8e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 GAN01713.1 - 1.7e-05 25.1 0.3 0.22 11.8 0.1 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAN01713.1 - 2.1e-05 25.0 0.5 0.42 11.0 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.23 GAN01713.1 - 5.2e-05 23.4 2.3 0.049 13.7 0.0 3.7 4 0 0 4 4 3 1 Dynamin family AAA_28 PF13521.6 GAN01713.1 - 0.00014 22.2 0.0 0.032 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN01713.1 - 0.00032 21.0 0.0 2.5 8.5 0.0 3.6 3 0 0 3 3 3 2 RNA helicase MeaB PF03308.16 GAN01713.1 - 0.00084 18.4 0.2 0.24 10.3 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 GAN01713.1 - 0.0012 19.0 3.7 1.8 8.7 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 GAN01713.1 - 0.0014 19.2 0.2 2.4 8.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 GAN01713.1 - 0.002 18.2 1.4 1.4 9.0 0.4 3.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_27 PF13514.6 GAN01713.1 - 0.0022 17.6 0.0 2.8 7.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 GAN01713.1 - 0.0022 17.3 0.4 1.1 8.5 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin AAA_15 PF13175.6 GAN01713.1 - 0.0034 17.2 4.6 0.73 9.5 0.1 3.2 4 1 0 4 4 2 2 AAA ATPase domain AAA_24 PF13479.6 GAN01713.1 - 0.0037 17.0 0.0 2 8.1 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 GAN01713.1 - 0.0063 16.2 2.4 0.86 9.3 0.1 3.3 4 0 0 4 4 3 1 AAA domain Septin PF00735.18 GAN01713.1 - 0.0081 15.5 0.1 8.8 5.5 0.0 3.2 3 0 0 3 3 3 0 Septin NACHT PF05729.12 GAN01713.1 - 0.0084 16.0 0.6 0.92 9.4 0.0 2.9 3 0 0 3 3 2 1 NACHT domain SbcCD_C PF13558.6 GAN01713.1 - 0.015 15.5 0.2 2.8 8.2 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 GAN01713.1 - 0.027 14.7 0.0 15 5.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLASP_N PF12348.8 GAN01713.1 - 0.031 13.9 0.0 0.42 10.1 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal AAA_7 PF12775.7 GAN01713.1 - 0.035 13.6 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 GAN01713.1 - 0.06 13.3 0.2 4 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 GAN01713.1 - 0.066 13.6 0.2 10 6.6 0.0 3.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GAN01713.1 - 0.076 12.2 0.1 7 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Vac14_Fab1_bd PF12755.7 GAN01713.1 - 0.086 13.4 0.1 11 6.7 0.0 3.5 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region cobW PF02492.19 GAN01713.1 - 0.092 12.3 2.3 18 4.9 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAN01713.1 - 0.12 11.6 1.4 2.9 7.0 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain FeoB_N PF02421.18 GAN01713.1 - 0.12 11.8 0.3 14 5.2 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B MukB PF04310.12 GAN01713.1 - 0.13 12.1 0.4 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal ATP_bind_1 PF03029.17 GAN01713.1 - 3.7 7.3 4.8 8 6.2 0.3 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF2613 PF11021.8 GAN01715.1 - 0.031 14.4 0.4 0.031 14.4 0.4 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) SKG6 PF08693.10 GAN01715.1 - 0.19 11.2 1.2 0.73 9.3 1.2 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain tRNA_edit PF04073.15 GAN01717.1 - 8.6e-10 38.8 0.0 2.1e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain UPRTase PF14681.6 GAN01718.1 - 9.5e-60 201.6 0.0 1.6e-45 155.1 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pep3_Vps18 PF05131.14 GAN01719.1 - 2.2e-50 170.3 0.2 7.5e-50 168.6 0.1 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 GAN01719.1 - 1.9e-12 47.3 12.0 2.2e-09 37.4 4.0 4.0 3 2 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 GAN01719.1 - 0.00067 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 GAN01719.1 - 0.036 13.9 7.4 0.018 14.9 4.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAN01719.1 - 0.076 12.6 1.7 0.19 11.4 1.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 GAN01719.1 - 0.11 12.2 5.8 0.36 10.6 5.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 GAN01719.1 - 0.19 12.0 1.1 0.53 10.6 1.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN01719.1 - 0.31 11.0 2.3 0.92 9.5 2.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAN01719.1 - 2.9 8.3 8.2 0.19 12.1 2.7 1.9 2 0 0 2 2 2 0 Ring finger domain RicinB_lectin_2 PF14200.6 GAN01720.1 - 3.5e-25 88.5 3.4 2.6e-10 40.9 0.0 2.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN01720.1 - 8.6e-17 61.6 1.5 7.6e-09 35.9 0.0 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Gal_GalNac_35kD PF17337.2 GAN01720.1 - 0.0031 17.6 0.1 0.36 10.8 0.0 2.7 1 1 2 3 3 3 2 Galactose-inhibitable lectin 35 kDa subunit Pkinase PF00069.25 GAN01721.1 - 5.8e-55 186.5 0.0 5.8e-55 186.5 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01721.1 - 3.7e-24 85.4 0.1 1.2e-23 83.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN01721.1 - 4.3e-12 45.9 0.0 1.5e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN01721.1 - 0.038 13.9 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family GAS PF13851.6 GAN01721.1 - 0.082 12.2 76.7 0.046 13.1 12.6 5.5 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding HrpB7 PF09486.10 GAN01721.1 - 4.6 7.6 42.2 0.13 12.6 10.6 5.2 3 1 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) Pkinase PF00069.25 GAN01722.1 - 4.7e-76 255.6 0.0 5.3e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01722.1 - 6.7e-36 123.9 0.0 8.6e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN01722.1 - 0.00031 19.8 0.0 0.0014 17.6 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN01722.1 - 0.0074 15.6 0.2 0.018 14.3 0.1 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 GAN01722.1 - 0.073 12.4 0.5 0.14 11.5 0.5 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN01722.1 - 0.084 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family bZIP_2 PF07716.15 GAN01723.1 - 1.8e-08 34.3 18.6 1.8e-08 34.3 15.9 2.3 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 GAN01723.1 - 5.6e-08 32.8 15.5 2e-07 31.0 14.7 2.2 1 1 1 2 2 2 2 bZIP transcription factor KASH_CCD PF14662.6 GAN01723.1 - 0.00075 19.4 7.2 0.00075 19.4 7.2 1.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Prefoldin_2 PF01920.20 GAN01723.1 - 0.0037 17.2 4.3 0.0099 15.8 4.3 1.8 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.12 GAN01723.1 - 0.0067 16.5 15.6 0.019 15.0 15.6 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein bZIP_Maf PF03131.17 GAN01723.1 - 0.029 14.9 13.2 0.04 14.4 12.0 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor NAM-associated PF14303.6 GAN01723.1 - 0.066 13.9 11.4 0.11 13.2 11.4 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PI3K_1B_p101 PF10486.9 GAN01723.1 - 0.079 10.7 7.8 0.094 10.5 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3439 PF11921.8 GAN01723.1 - 0.09 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SR-25 PF10500.9 GAN01723.1 - 0.1 12.2 13.7 0.22 11.1 13.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC-167 PF15188.6 GAN01723.1 - 0.23 11.8 6.9 0.13 12.7 4.5 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 PA26 PF04636.13 GAN01723.1 - 0.32 9.9 4.5 0.4 9.6 4.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) STAC2_u1 PF16664.5 GAN01723.1 - 0.33 11.4 8.9 0.73 10.3 8.5 1.9 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 UPF0242 PF06785.11 GAN01723.1 - 0.36 10.9 10.0 0.58 10.2 10.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SOBP PF15279.6 GAN01723.1 - 0.61 10.6 6.9 0.89 10.1 6.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF5320 PF17253.2 GAN01723.1 - 0.68 11.0 4.4 0.63 11.1 2.4 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF724 PF05266.14 GAN01723.1 - 1.3 8.8 13.4 2.2 8.1 13.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 GAN01723.1 - 1.4 8.7 10.2 0.42 10.4 5.4 2.4 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 GAN01723.1 - 3.2 8.3 13.4 5.1 7.6 13.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 GAN01723.1 - 3.7 6.8 10.6 4.9 6.4 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 GAN01723.1 - 4.1 6.6 12.5 6.6 6.0 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Chibby PF14645.6 GAN01723.1 - 7.5 7.0 11.0 21 5.5 11.0 1.7 1 1 0 1 1 1 0 Chibby family Cas_Csa4 PF09703.10 GAN01724.1 - 0.035 13.4 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) KIAA1430 PF13879.6 GAN01724.1 - 1.4 9.7 15.6 0.091 13.5 3.9 3.2 1 1 1 2 2 2 0 KIAA1430 homologue TFIIA PF03153.13 GAN01724.1 - 3.4 7.6 28.0 0.11 12.5 22.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cyto_heme_lyase PF01265.17 GAN01725.1 - 2e-59 201.6 14.5 1.1e-58 199.2 14.5 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MIP PF00230.20 GAN01726.1 - 1.1e-48 165.9 17.6 1.4e-48 165.6 17.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein C_GCAxxG_C_C PF09719.10 GAN01726.1 - 0.039 14.2 0.1 0.082 13.2 0.1 1.6 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) CUE PF02845.16 GAN01727.1 - 1.8e-07 30.7 0.2 0.00056 19.6 0.5 2.6 2 0 0 2 2 2 2 CUE domain DUF1771 PF08590.10 GAN01727.1 - 3.1e-07 30.6 2.3 3.1e-07 30.6 2.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 GAN01727.1 - 1.3e-06 28.7 0.0 3.8e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Smr domain UBA PF00627.31 GAN01727.1 - 0.0059 16.5 0.1 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 UBA/TS-N domain Methyltransf_16 PF10294.9 GAN01728.1 - 9.9e-28 97.0 0.0 1.5e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAN01728.1 - 0.00055 19.8 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN01728.1 - 0.018 15.8 0.0 0.076 13.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 GAN01728.1 - 0.045 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 GAN01728.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Linocin_M18 PF04454.12 GAN01728.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase gag-asp_proteas PF13975.6 GAN01729.1 - 2.5e-06 28.0 0.9 8.5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAN01729.1 - 5.3e-06 27.0 0.9 9.9e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GAN01729.1 - 0.0004 20.2 0.5 0.00065 19.5 0.5 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 GAN01729.1 - 0.0029 17.4 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GAN01729.1 - 0.0091 16.3 0.2 0.039 14.3 0.0 2.0 2 1 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.27 GAN01730.1 - 4.4e-24 85.2 0.2 5.4e-24 85.0 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GAN01731.1 - 2.3e-71 240.3 0.0 5.4e-71 239.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01731.1 - 1.7e-40 139.0 0.0 3.5e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN01731.1 - 8.7e-06 25.3 1.9 2.4e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 GAN01731.1 - 0.021 13.6 1.6 0.16 10.7 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase PBP_GOBP PF01395.22 GAN01731.1 - 0.032 14.4 0.0 0.88 9.7 0.0 2.6 2 0 0 2 2 2 0 PBP/GOBP family Seadorna_VP7 PF07387.11 GAN01731.1 - 0.082 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_1 PF00515.28 GAN01732.1 - 2.5e-26 90.4 20.9 9.1e-07 28.4 0.1 6.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAN01732.1 - 5.4e-20 69.8 21.2 3.1e-05 23.8 0.1 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat STI1 PF17830.1 GAN01732.1 - 4.3e-16 58.6 4.2 4.3e-16 58.6 4.2 2.1 2 0 0 2 2 2 1 STI1 domain TPR_12 PF13424.6 GAN01732.1 - 5.8e-14 52.1 15.1 3.6e-10 40.0 0.2 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN01732.1 - 8.5e-12 44.6 9.8 2e-05 24.2 0.2 4.5 4 0 0 4 4 4 3 TPR repeat TPR_17 PF13431.6 GAN01732.1 - 4e-10 39.4 5.8 0.22 12.0 0.1 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN01732.1 - 1.1e-09 38.2 5.2 0.16 12.9 0.1 6.3 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN01732.1 - 3.5e-09 36.1 20.4 3.7e-05 23.6 0.3 6.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAN01732.1 - 1.5e-07 30.9 6.8 0.00026 20.8 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN01732.1 - 2.4e-07 31.1 10.2 0.25 11.9 0.0 5.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAN01732.1 - 3.1e-07 30.9 4.5 0.023 15.3 0.2 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAN01732.1 - 1e-06 28.4 5.3 0.011 15.6 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN01732.1 - 2.7e-06 27.5 9.6 0.0021 18.2 0.9 3.4 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GAN01732.1 - 0.012 15.8 1.6 0.31 11.2 0.2 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat Peptidase_M74 PF03411.13 GAN01732.1 - 0.022 14.3 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Poxvirus PF06227.12 GAN01732.1 - 0.057 13.2 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 dsDNA Poxvirus TPR_6 PF13174.6 GAN01732.1 - 0.064 13.9 11.1 0.81 10.5 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 GAN01732.1 - 0.23 11.8 0.4 4.9 7.6 0.0 3.3 3 0 0 3 3 3 0 PPR repeat ubiquitin PF00240.23 GAN01735.1 - 3e-19 68.5 0.0 3.4e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAN01735.1 - 2.9e-08 33.4 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GAN01735.1 - 0.005 16.9 0.1 2.8 8.0 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_2 PF14560.6 GAN01735.1 - 0.04 14.4 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Aldedh PF00171.22 GAN01737.1 - 1.7e-185 616.9 0.0 2e-185 616.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAN01737.1 - 0.0097 15.4 0.0 4.9 6.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) ThrE PF06738.12 GAN01738.1 - 9.4e-48 162.7 14.7 6.3e-43 146.9 0.5 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAN01738.1 - 1.3e-05 25.4 23.4 2.3e-05 24.6 10.4 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Methyltransf_15 PF09445.10 GAN01739.1 - 2.2e-44 150.9 0.0 3.8e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 GAN01739.1 - 6.6e-07 29.2 0.0 4e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 GAN01739.1 - 7.1e-07 29.8 0.0 2.2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAN01739.1 - 9.5e-06 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 GAN01739.1 - 0.0012 19.5 0.0 0.0036 17.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAN01739.1 - 0.0019 17.7 0.0 0.0019 17.7 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 GAN01739.1 - 0.0024 17.8 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Arrestin_N PF00339.29 GAN01740.1 - 9.3e-14 51.7 0.6 2.3e-06 27.7 0.1 3.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN01740.1 - 3.6e-12 46.9 3.1 3.5e-07 30.7 1.5 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 GAN01740.1 - 4.9e-06 26.2 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 2 SpoOM protein Vps26 PF03643.15 GAN01740.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 F-actin_cap_A PF01267.17 GAN01741.1 - 1.8e-100 335.8 2.9 2e-100 335.6 2.9 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Imm30 PF15565.6 GAN01741.1 - 0.23 11.5 2.4 2 8.6 0.2 3.2 3 1 1 4 4 4 0 Immunity protein 30 Bin3 PF06859.12 GAN01743.1 - 2.1e-32 111.9 0.0 4.7e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 GAN01743.1 - 1.4e-12 47.6 0.2 1.1e-07 31.7 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GAN01743.1 - 4.6e-12 46.1 0.0 6.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN01743.1 - 4.9e-11 43.2 0.0 5.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAN01743.1 - 2.5e-08 34.5 0.0 0.0038 17.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAN01743.1 - 2.5e-07 31.3 0.0 0.012 16.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 GAN01743.1 - 2.3e-06 27.2 0.1 6.1e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GAN01743.1 - 1.2e-05 25.3 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAN01743.1 - 1.8e-05 24.3 0.2 3e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 GAN01743.1 - 4.7e-05 22.8 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 GAN01743.1 - 0.0048 16.4 0.0 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_PK PF05891.12 GAN01743.1 - 0.027 14.0 0.0 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Spermine_synth PF01564.17 GAN01743.1 - 0.093 12.1 0.1 0.39 10.1 0.0 2.0 3 0 0 3 3 3 0 Spermine/spermidine synthase domain PCMT PF01135.19 GAN01743.1 - 0.11 12.3 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 GAN01743.1 - 0.19 11.3 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DUF3591 PF12157.8 GAN01744.1 - 8.3e-177 588.3 0.0 1.5e-176 587.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) TBP-binding PF09247.11 GAN01744.1 - 4.9e-09 36.3 0.3 1.5e-08 34.7 0.3 1.9 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 GAN01744.1 - 3.6e-06 26.7 0.7 8.8e-06 25.5 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAN01744.1 - 0.3 11.2 2.9 0.59 10.3 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF733 PF05306.11 GAN01744.1 - 3.8 7.9 10.0 0.62 10.4 4.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF733) zf-C2H2 PF00096.26 GAN01745.1 - 5.6e-19 67.5 30.0 8.2e-06 26.0 1.6 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN01745.1 - 4.8e-17 61.5 29.9 2.1e-06 27.9 0.5 5.6 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN01745.1 - 3.3e-11 43.0 29.1 0.00095 19.8 1.8 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 GAN01745.1 - 1.1e-05 26.0 21.4 0.028 15.1 0.6 4.5 2 1 2 4 4 4 3 FOXP coiled-coil domain zf-met PF12874.7 GAN01745.1 - 0.012 16.0 10.0 13 6.3 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN01745.1 - 0.02 15.2 11.9 4.8 7.6 0.9 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding NUDE_C PF04880.13 GAN01745.1 - 0.11 13.0 7.8 0.081 13.4 3.8 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region zf-C2H2_aberr PF17017.5 GAN01745.1 - 2.7 8.1 7.0 3 7.9 0.1 3.3 2 1 2 4 4 4 0 Aberrant zinc-finger JAB PF01398.21 GAN01746.1 - 8e-15 54.9 0.1 2.8e-14 53.1 0.0 2.0 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease IATP PF04568.12 GAN01747.1 - 0.0017 18.7 4.0 0.0021 18.5 3.6 1.5 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Ribosomal_L18 PF17135.4 GAN01748.1 - 5e-88 293.4 5.3 6e-88 293.2 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAN01748.1 - 0.0013 19.4 0.7 0.0036 18.0 0.7 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-C2H2 PF00096.26 GAN01749.1 - 0.0019 18.5 67.4 0.011 16.1 1.2 8.7 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAN01749.1 - 0.0081 16.4 0.8 0.0081 16.4 0.8 8.2 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAN01749.1 - 0.047 14.5 65.5 0.18 12.7 1.0 8.4 8 0 0 8 8 8 0 C2H2-type zinc finger zf_UBZ PF18439.1 GAN01749.1 - 0.96 9.1 24.4 26 4.5 0.0 7.7 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger DUF678 PF05077.12 GAN01749.1 - 5.2 7.3 7.4 76 3.5 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF678) ABC2_membrane PF01061.24 GAN01750.1 - 2.1e-38 131.9 23.8 2.1e-38 131.9 23.8 1.7 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAN01750.1 - 9.6e-29 100.6 0.0 2.2e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAN01750.1 - 1.1e-05 25.4 0.0 0.094 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN01750.1 - 0.00058 19.4 0.0 0.12 11.8 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAN01750.1 - 0.00064 19.7 0.1 0.0021 18.0 0.1 1.9 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 GAN01750.1 - 0.00072 19.5 0.1 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 GAN01750.1 - 0.0016 18.1 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAN01750.1 - 0.0052 17.2 0.2 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 GAN01750.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAN01750.1 - 0.0085 16.6 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN01750.1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAN01750.1 - 0.038 13.9 0.1 0.082 12.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 GAN01750.1 - 0.048 14.2 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 GAN01750.1 - 0.056 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.6 GAN01750.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAN01750.1 - 0.07 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAN01750.1 - 0.087 13.2 0.2 0.56 10.6 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAN01750.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 GAN01750.1 - 0.12 11.9 0.3 0.28 10.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAN01750.1 - 0.28 11.3 0.9 0.55 10.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAN01750.1 - 0.36 10.5 2.9 0.18 11.5 0.2 1.7 2 0 0 2 2 2 0 AAA domain Herpes_UL92 PF03048.14 GAN01750.1 - 1 9.1 8.3 0.23 11.2 4.3 2.1 2 1 1 3 3 3 0 UL92 family ABC2_membrane_3 PF12698.7 GAN01750.1 - 6.7 5.7 34.6 6.1 5.8 32.0 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein Hist_deacetyl PF00850.19 GAN01751.1 - 1.8e-75 254.3 0.0 3.7e-75 253.3 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain CPDase PF07823.11 GAN01751.1 - 0.0034 17.1 0.3 0.34 10.6 0.3 2.2 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein Tudor-knot PF11717.8 GAN01751.1 - 0.095 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF2897 PF11446.8 GAN01753.1 - 2.2 8.2 4.1 4.3 7.3 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) SNARE PF05739.19 GAN01753.1 - 3 7.9 9.0 5.9 7.0 9.0 1.5 1 0 0 1 1 1 0 SNARE domain ApbA PF02558.16 GAN01754.1 - 3.5e-27 94.9 0.0 4.9e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAN01754.1 - 1.4e-26 93.1 0.3 2.1e-26 92.5 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.23 GAN01754.1 - 0.002 18.1 0.0 0.011 15.8 0.0 2.2 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 GAN01754.1 - 0.01 15.8 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 GAN01754.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAN01754.1 - 0.06 13.9 0.0 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Na_sulph_symp PF00939.19 GAN01755.1 - 1.3e-94 317.9 26.9 1.5e-94 317.7 26.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN01755.1 - 2e-19 69.9 25.9 1.4e-12 47.5 5.6 2.2 1 1 1 2 2 2 2 Citrate transporter Neurokinin_B PF03823.14 GAN01755.1 - 0.4 10.8 2.1 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Neurokinin B Choline_transpo PF04515.12 GAN01756.1 - 2e-72 244.2 41.9 2e-72 244.2 41.9 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 GAN01756.1 - 1.1 9.9 5.0 3.1 8.4 5.0 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPP1-like PF11833.8 GAN01756.1 - 4.3 6.9 13.0 0.12 12.0 1.8 2.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zn_clus PF00172.18 GAN01757.1 - 2.7e-09 37.0 9.3 5.5e-09 36.0 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carboxyl_trans PF01039.22 GAN01758.1 - 7.3e-115 384.4 0.1 9e-115 384.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain NTP_transf_2 PF01909.23 GAN01760.1 - 1.6e-06 28.3 0.0 4.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAN01760.1 - 0.014 15.4 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 GAN01760.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase beta palm ThiF PF00899.21 GAN01761.1 - 1.1e-19 70.7 0.0 2e-19 70.0 0.0 1.3 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 GAN01761.1 - 0.0085 16.3 0.2 0.16 12.1 0.2 2.8 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle Bap31_Bap29_C PF18035.1 GAN01761.1 - 0.045 13.8 0.1 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Hexokinase_2 PF03727.16 GAN01762.1 - 3.3e-83 278.8 0.1 5e-83 278.2 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN01762.1 - 7.3e-68 228.4 0.0 1.1e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase GDP_Man_Dehyd PF16363.5 GAN01763.1 - 1.2e-61 208.9 0.0 1.4e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAN01763.1 - 2.1e-53 181.2 0.0 2.6e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN01763.1 - 2.8e-16 59.4 0.0 1.8e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAN01763.1 - 6.5e-15 55.0 0.0 1.3e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAN01763.1 - 4.2e-09 35.9 0.0 6.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAN01763.1 - 5e-09 35.9 0.0 1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN01763.1 - 1.8e-07 31.2 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAN01763.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAN01763.1 - 2.5e-05 23.6 0.0 0.0024 17.1 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 GAN01763.1 - 0.0041 16.7 0.4 0.088 12.4 0.5 2.5 2 1 0 2 2 2 1 NmrA-like family Cys_Met_Meta_PP PF01053.20 GAN01763.1 - 0.06 11.9 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IBN_N PF03810.19 GAN01764.1 - 2.2e-15 56.3 0.1 1.2e-14 54.0 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAN01764.1 - 0.0002 21.4 1.2 0.0002 21.4 1.2 4.0 4 1 1 5 5 5 1 Exportin 1-like protein Paf1 PF03985.13 GAN01764.1 - 0.0092 15.0 13.3 0.014 14.4 13.3 1.3 1 0 0 1 1 1 1 Paf1 RIX1 PF08167.12 GAN01764.1 - 0.01 15.6 1.0 0.41 10.4 0.1 3.4 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 GAN01764.1 - 0.027 14.7 0.4 0.5 10.6 0.0 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 SDA1 PF05285.12 GAN01764.1 - 0.032 13.6 27.5 0.053 12.9 27.5 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GAN01764.1 - 0.033 13.6 19.1 0.05 13.0 19.1 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAN01764.1 - 0.11 10.7 29.9 0.2 9.8 29.9 1.4 1 0 0 1 1 1 0 Nop14-like family Cnd1 PF12717.7 GAN01764.1 - 0.22 11.6 3.7 0.59 10.2 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CDC45 PF02724.14 GAN01764.1 - 0.51 8.6 17.9 0.94 7.7 17.9 1.4 1 0 0 1 1 1 0 CDC45-like protein CTD_bind PF04818.13 GAN01765.1 - 3.5e-11 43.7 1.5 4.2e-11 43.5 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Macoilin PF09726.9 GAN01765.1 - 0.3 9.6 1.9 0.4 9.2 1.9 1.1 1 0 0 1 1 1 0 Macoilin family Myb_DNA-binding PF00249.31 GAN01766.1 - 5.6e-46 154.5 18.0 4.8e-16 58.7 2.9 5.2 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN01766.1 - 2.3e-36 123.8 15.7 6.1e-14 52.0 2.0 4.2 2 1 2 4 4 4 4 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAN01766.1 - 2.9e-07 30.6 8.9 0.011 15.9 0.2 4.6 2 2 3 5 5 5 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 GAN01766.1 - 1.9e-06 27.8 8.6 7.2e-05 22.8 0.2 3.9 2 1 2 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 GAN01766.1 - 7.3e-05 22.6 16.5 0.025 14.4 1.4 4.7 1 1 3 4 4 4 2 Myb DNA-binding like HTH_40 PF14493.6 GAN01766.1 - 0.018 15.5 2.8 1.2 9.7 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain D5_N PF08706.11 GAN01766.1 - 0.029 14.6 5.8 1.2 9.3 5.8 2.5 1 1 0 1 1 1 0 D5 N terminal like DUF3606 PF12244.8 GAN01766.1 - 0.035 14.0 0.3 65 3.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3606) Atg29_N PF18388.1 GAN01766.1 - 0.054 13.3 5.5 0.055 13.3 0.3 3.0 3 0 0 3 3 3 0 Atg29 N-terminal domain SnAPC_2_like PF11035.8 GAN01766.1 - 0.36 10.9 6.9 0.076 13.2 1.4 2.4 2 1 1 3 3 3 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF5611 PF18446.1 GAN01766.1 - 0.52 11.2 5.5 14 6.6 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5611) Glyco_transf_15 PF01793.16 GAN01767.1 - 1.5e-111 372.8 8.8 1.9e-111 372.4 8.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Raptor_N PF14538.6 GAN01768.1 - 1e-66 223.4 0.0 1.9e-66 222.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 GAN01768.1 - 4e-14 52.8 8.1 0.00062 20.5 0.2 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT_2 PF13646.6 GAN01768.1 - 5.1e-07 30.0 0.4 0.00057 20.2 0.1 3.6 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 GAN01768.1 - 5.6e-07 29.3 8.5 0.0067 16.6 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 GAN01768.1 - 7.1e-06 26.2 0.0 0.0018 18.3 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 GAN01768.1 - 0.00021 21.5 0.2 12 6.3 0.1 4.6 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAN01768.1 - 0.034 14.2 0.2 14 5.8 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region HEAT_EZ PF13513.6 GAN01768.1 - 0.12 12.9 2.3 1.2 9.7 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat Exo_endo_phos PF03372.23 GAN01769.1 - 1.3e-20 73.9 0.4 1.2e-19 70.8 0.4 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 GAN01769.1 - 4.8e-07 29.4 11.3 0.00038 20.2 2.9 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAN01769.1 - 6.3e-07 29.6 14.2 0.0042 17.5 2.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN01769.1 - 0.34 11.6 8.3 18 6.4 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat Acyl-CoA_dh_1 PF00441.24 GAN01770.1 - 1e-45 155.6 3.0 1e-45 155.6 3.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAN01770.1 - 7.9e-28 97.4 0.7 2.7e-27 95.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAN01770.1 - 1.4e-21 76.5 0.1 3.3e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAN01770.1 - 2.2e-19 70.1 0.3 2.2e-19 70.1 0.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain NIF3 PF01784.18 GAN01771.1 - 1.3e-69 234.6 0.0 1.6e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) NAD_binding_10 PF13460.6 GAN01772.1 - 5e-05 23.3 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN01772.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family ATPgrasp_YheCD PF14398.6 GAN01772.1 - 0.033 13.4 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Y_phosphatase PF00102.27 GAN01773.1 - 1.6e-69 234.1 7.6 4e-69 232.8 7.6 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RabGAP-TBC PF00566.18 GAN01773.1 - 8.7e-41 139.9 0.0 8.7e-41 139.9 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 GAN01773.1 - 1.9e-28 99.6 0.0 3.7e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Rhodanese PF00581.20 GAN01773.1 - 1.7e-19 70.3 0.1 6e-08 33.2 0.0 3.7 3 0 0 3 3 3 2 Rhodanese-like domain Pkinase_Tyr PF07714.17 GAN01773.1 - 1.5e-16 60.5 0.0 5.4e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.20 GAN01773.1 - 4.6e-05 23.3 0.3 0.00015 21.6 0.3 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAN01773.1 - 0.067 13.3 1.8 0.62 10.2 0.1 3.3 2 1 1 3 3 3 0 Inositol hexakisphosphate SYF2 PF08231.12 GAN01774.1 - 6.1e-22 78.7 8.1 6.1e-22 78.7 8.1 2.8 2 1 1 3 3 3 1 SYF2 splicing factor RE_TaqI PF09573.10 GAN01774.1 - 0.021 14.6 4.4 0.044 13.6 4.4 1.5 1 0 0 1 1 1 0 TaqI restriction endonuclease LRR_6 PF13516.6 GAN01775.1 - 0.00025 20.8 0.9 0.016 15.3 0.1 3.1 2 0 0 2 2 2 2 Leucine Rich repeat Acetyltransf_1 PF00583.25 GAN01777.1 - 4.1e-05 23.8 0.1 7.7e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN01777.1 - 0.0036 17.7 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN01777.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FUSC_2 PF13515.6 GAN01778.1 - 5.9e-20 71.7 8.0 5.9e-20 71.7 8.0 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAN01778.1 - 2.5e-11 42.9 3.0 2.5e-11 42.9 3.0 3.9 3 2 0 4 4 4 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 GAN01778.1 - 1.7e-10 41.1 0.1 3.5e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 GAN01778.1 - 1.2e-09 37.5 0.5 1.2e-09 37.5 0.5 4.1 3 1 1 4 4 4 2 Aluminium activated malate transporter ArAE_2_N PF10337.9 GAN01778.1 - 6.6e-08 32.0 0.1 6.6e-08 32.0 0.1 3.0 3 1 1 4 4 4 1 Putative ER transporter, 6TM, N-terminal Holin_BhlA PF10960.8 GAN01778.1 - 0.061 13.3 0.1 0.63 10.0 0.0 2.8 2 0 0 2 2 2 0 BhlA holin family SR-25 PF10500.9 GAN01778.1 - 2.1 7.9 24.8 0.041 13.5 5.3 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein ArAE_1 PF06081.11 GAN01778.1 - 5.1 7.2 14.5 0.018 15.2 3.6 2.6 3 1 0 3 3 3 0 Aromatic acid exporter family member 1 SLC12 PF03522.15 GAN01778.1 - 8.4 5.3 14.7 0.47 9.4 1.3 2.2 2 0 0 2 2 2 0 Solute carrier family 12 SHR3_chaperone PF08229.11 GAN01779.1 - 4e-37 127.0 1.0 4.4e-37 126.9 1.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Saf_2TM PF18303.1 GAN01779.1 - 0.063 12.9 1.1 2.7 7.6 0.2 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Aminotran_5 PF00266.19 GAN01780.1 - 1.3e-20 73.7 0.0 1.7e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 GAN01780.1 - 0.0037 15.9 0.0 0.0061 15.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 GAN01780.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SICA_C PF12879.7 GAN01783.1 - 0.018 15.1 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain Herpes_LMP2 PF07415.11 GAN01783.1 - 0.54 9.0 1.6 0.76 8.5 1.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein PALP PF00291.25 GAN01785.1 - 2.4e-61 207.7 0.3 4.1e-61 207.0 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SUIM_assoc PF16619.5 GAN01785.1 - 0.0036 17.3 0.0 0.014 15.4 0.0 2.0 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DAGK_cat PF00781.24 GAN01785.1 - 0.13 11.9 0.1 0.38 10.4 0.1 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Mito_fiss_reg PF05308.11 GAN01785.1 - 2.1 8.4 12.5 3.2 7.7 12.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator FancD2 PF14631.6 GAN01786.1 - 8.3e-212 706.2 31.1 8.3e-212 706.2 31.1 2.5 2 1 0 2 2 2 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 GAN01786.1 - 0.041 14.2 8.3 0.25 11.7 0.0 4.6 4 0 0 4 4 4 0 FANCI solenoid 2 HLH PF00010.26 GAN01787.1 - 2.2e-17 62.7 0.0 2e-16 59.7 0.0 2.6 2 2 0 2 2 2 1 Helix-loop-helix DNA-binding domain F-box-like PF12937.7 GAN01788.1 - 0.00074 19.4 0.1 0.0022 17.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN01788.1 - 0.0032 17.3 1.1 0.011 15.6 0.2 2.4 2 0 0 2 2 2 1 F-box domain Ribonuc_red_lgC PF02867.15 GAN01789.1 - 1.9e-158 528.3 0.0 2.8e-158 527.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAN01789.1 - 2.3e-18 66.0 0.1 6.2e-18 64.6 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAN01789.1 - 8.2e-14 52.0 0.6 4.2e-13 49.7 0.0 2.6 3 0 0 3 3 3 1 ATP cone domain SUR7 PF06687.12 GAN01791.1 - 7.7e-12 45.3 9.9 1.2e-11 44.7 9.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF1461 PF07314.11 GAN01791.1 - 0.79 9.6 4.6 1.2 9.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Phage_holin_3_6 PF07332.11 GAN01791.1 - 4.2 7.4 14.6 1.8 8.6 12.1 1.6 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Amidohydro_1 PF01979.20 GAN01792.1 - 0.023 14.0 0.9 0.026 13.8 0.9 1.1 1 0 0 1 1 1 0 Amidohydrolase family Aa_trans PF01490.18 GAN01793.1 - 6.7e-80 268.8 36.5 8e-80 268.5 36.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 GAN01793.1 - 1.8e-11 43.5 44.0 5.9e-11 41.8 44.0 1.7 1 1 0 1 1 1 1 Amino acid permease VIT1 PF01988.19 GAN01793.1 - 0.022 14.7 0.2 0.022 14.7 0.2 3.3 3 2 0 3 3 3 0 VIT family Sec20 PF03908.13 GAN01793.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Sec20 Mito_carr PF00153.27 GAN01794.1 - 1.3e-27 95.6 6.5 1.2e-12 47.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SET PF00856.28 GAN01795.1 - 2e-08 34.8 2.6 0.00085 19.7 0.0 3.1 2 2 1 3 3 3 2 SET domain Zip PF02535.22 GAN01795.1 - 0.15 11.3 2.6 0.29 10.3 2.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter zf-C2H2_2 PF12756.7 GAN01796.1 - 6.2e-07 29.7 21.9 0.0017 18.7 0.0 4.9 3 3 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN01796.1 - 2.1e-05 25.0 54.3 0.24 12.3 1.8 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN01796.1 - 0.0014 18.9 52.4 0.0041 17.4 2.2 6.8 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN01796.1 - 0.0023 18.2 43.4 0.03 14.7 2.3 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAN01796.1 - 0.0059 17.0 56.6 0.049 14.1 1.5 6.9 6 0 0 6 6 6 4 Zinc finger, C2H2 type Longin PF13774.6 GAN01796.1 - 0.28 11.3 1.4 1.4 9.0 0.5 2.5 2 0 0 2 2 2 0 Regulated-SNARE-like domain Snf7 PF03357.21 GAN01797.1 - 1.2e-26 93.4 20.9 1.2e-26 93.4 20.9 1.8 1 1 1 2 2 2 1 Snf7 CEP19 PF14933.6 GAN01797.1 - 2.8 8.2 7.9 7.7 6.8 7.9 1.7 1 1 0 1 1 1 0 CEP19-like protein Aldo_ket_red PF00248.21 GAN01798.1 - 2.1e-55 188.0 0.2 2.1e-54 184.8 0.2 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 GAN01798.1 - 0.01 16.1 0.1 0.16 12.3 0.0 2.5 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Cro PF09048.10 GAN01798.1 - 0.14 12.2 0.4 40 4.4 0.2 3.1 3 0 0 3 3 3 0 Cro TMEM164 PF14808.6 GAN01799.1 - 2.1e-13 50.2 0.1 2.8e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.10 GAN01799.1 - 1.6e-05 24.5 3.4 2.1e-05 24.2 3.4 1.1 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF2838 PF10998.8 GAN01799.1 - 0.004 17.4 0.4 0.004 17.4 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) BSP_II PF05432.11 GAN01800.1 - 1.2 8.8 14.4 2.1 8.0 6.2 2.4 2 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 GAN01800.1 - 7.5 6.2 9.9 1.1 8.9 2.8 2.2 2 0 0 2 2 2 0 FAM176 family ERCC4 PF02732.15 GAN01801.1 - 1e-23 84.3 0.1 1e-23 84.3 0.1 2.4 2 0 0 2 2 2 1 ERCC4 domain SUIM_assoc PF16619.5 GAN01801.1 - 0.0029 17.7 4.4 0.017 15.2 4.4 2.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 HTH_45 PF14947.6 GAN01801.1 - 0.011 15.7 0.1 0.035 14.1 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DUF1495 PF07381.11 GAN01801.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) MutL PF13941.6 GAN01801.1 - 0.14 10.7 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 MutL protein Spem1 PF15670.5 GAN01801.1 - 7.6 6.0 13.5 4.8 6.7 1.4 3.2 3 0 0 3 3 3 0 Spermatid maturation protein 1 WW PF00397.26 GAN01802.1 - 4.6e-05 23.4 11.4 0.00011 22.2 11.4 1.7 1 0 0 1 1 1 1 WW domain Pup PF05639.11 GAN01802.1 - 0.37 11.7 0.0 0.37 11.7 0.0 2.8 3 1 0 3 3 3 0 Pup-like protein Sel1 PF08238.12 GAN01803.1 - 5.3e-20 71.4 7.3 7.4e-07 29.7 1.4 3.3 3 0 0 3 3 3 3 Sel1 repeat zf-RVT PF13966.6 GAN01804.1 - 7.6e-08 33.0 1.9 1.5e-07 32.0 1.9 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Methyltransf_23 PF13489.6 GAN01805.1 - 5.1e-14 52.4 0.0 8.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN01805.1 - 8.8e-14 52.0 0.0 2.7e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN01805.1 - 2.4e-12 47.3 0.0 6e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN01805.1 - 7.6e-12 45.3 0.0 2e-10 40.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN01805.1 - 9.3e-09 35.9 0.0 3.9e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN01805.1 - 0.00012 21.5 0.0 0.00032 20.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN01805.1 - 0.00053 19.5 0.0 0.0059 16.1 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 GAN01805.1 - 0.00074 18.2 0.0 0.0014 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 GAN01805.1 - 0.054 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 GAN01805.1 - 0.091 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain SDH_alpha PF03313.15 GAN01805.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain CheR PF01739.18 GAN01805.1 - 0.19 11.2 0.3 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain KASH_CCD PF14662.6 GAN01806.1 - 0.0037 17.1 1.3 0.0037 17.1 1.3 3.0 3 0 0 3 3 3 2 Coiled-coil region of CCDC155 or KASH MIT PF04212.18 GAN01806.1 - 0.0047 17.0 1.0 0.0047 17.0 1.0 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Chibby PF14645.6 GAN01806.1 - 0.015 15.7 0.5 6.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Chibby family Ax_dynein_light PF10211.9 GAN01806.1 - 0.068 13.1 0.2 0.068 13.1 0.2 3.2 3 0 0 3 3 3 0 Axonemal dynein light chain YabA PF06156.13 GAN01806.1 - 0.16 12.6 14.8 0.69 10.6 1.9 3.7 3 1 0 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 GAN01806.1 - 1.2 8.4 15.2 0.26 10.6 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) kleA_kleC PF17383.2 GAN01806.1 - 1.2 9.5 6.8 8.2 6.8 1.1 2.9 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Cnn_1N PF07989.11 GAN01806.1 - 3.1 8.0 17.2 0.12 12.6 3.0 3.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 GAN01806.1 - 4 7.7 9.2 1.3 9.3 0.6 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Hydin_ADK PF17213.3 GAN01806.1 - 6.7 6.9 9.0 1 9.6 2.8 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain RPN7 PF10602.9 GAN01807.1 - 1.8e-36 125.4 1.0 1.5e-20 73.6 0.4 2.5 2 0 0 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.27 GAN01807.1 - 1.8e-19 70.2 2.7 2.7e-19 69.6 1.0 2.1 2 0 0 2 2 2 1 PCI domain DUF3834 PF12916.7 GAN01807.1 - 0.089 12.0 1.0 1.3 8.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3834) TPR_11 PF13414.6 GAN01807.1 - 0.089 12.5 0.5 18 5.1 0.0 2.6 2 0 0 2 2 2 0 TPR repeat RBP_receptor PF14752.6 GAN01808.1 - 6.3e-11 41.6 12.1 4.9e-10 38.6 12.1 2.2 1 1 0 1 1 1 1 Retinol binding protein receptor F-box-like PF12937.7 GAN01809.1 - 4.2e-08 33.0 0.1 8.7e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN01809.1 - 0.049 13.5 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 F-box domain Spc7 PF08317.11 GAN01811.1 - 1.8 7.4 48.8 0.62 8.9 11.8 3.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Mt_ATP-synt_D PF05873.12 GAN01811.1 - 5 6.9 21.6 0.15 11.9 5.3 4.2 2 2 1 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) Tropomyosin PF00261.20 GAN01811.1 - 9.8 5.5 42.2 0.55 9.6 1.9 4.1 2 1 2 4 4 4 0 Tropomyosin F-box-like PF12937.7 GAN01812.1 - 3.9e-11 42.7 0.6 1.4e-10 40.8 0.6 2.1 1 0 0 1 1 1 1 F-box-like Cyt-b5 PF00173.28 GAN01812.1 - 1.1e-10 41.5 0.0 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LRR_6 PF13516.6 GAN01812.1 - 5.2e-08 32.3 24.7 0.039 14.0 0.0 8.8 9 1 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 GAN01812.1 - 2.4e-07 30.9 21.4 0.81 10.2 0.2 7.1 5 2 5 10 10 10 5 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN01812.1 - 4.4e-06 26.4 1.4 8.1e-06 25.6 0.1 2.2 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 GAN01812.1 - 0.016 15.6 23.0 2.7 8.9 0.7 8.5 10 0 0 10 10 10 0 Leucine Rich Repeat Cation_efflux PF01545.21 GAN01813.1 - 6.6e-48 163.1 6.8 4.2e-47 160.4 6.8 2.0 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAN01813.1 - 4.4e-09 36.4 0.0 9.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Apo-CIII PF05778.12 GAN01813.1 - 0.09 12.4 0.1 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Ctr PF04145.15 GAN01814.1 - 6.8e-06 26.8 4.4 6.8e-06 26.8 4.4 1.9 1 1 1 2 2 2 1 Ctr copper transporter family Steroid_dh PF02544.16 GAN01815.1 - 2.4e-38 131.4 1.8 4.1e-38 130.7 1.8 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 GAN01815.1 - 5e-08 32.7 0.3 5e-08 32.7 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GAN01815.1 - 0.056 13.9 1.8 0.16 12.4 0.3 2.4 2 1 0 2 2 2 0 Phospholipid methyltransferase Myb_DNA-binding PF00249.31 GAN01816.1 - 3.7e-38 129.5 13.8 8.8e-10 38.6 1.8 5.5 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN01816.1 - 2.5e-32 110.9 2.0 2e-10 40.7 0.0 4.3 2 1 2 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAN01816.1 - 5.4e-10 39.0 2.3 0.0072 16.2 0.0 4.0 3 1 1 4 4 4 3 Myb DNA-binding like SANT_DAMP1_like PF16282.5 GAN01816.1 - 8.3e-08 32.3 5.4 0.077 13.2 0.1 4.9 3 2 2 5 5 5 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 GAN01816.1 - 0.00046 20.2 2.4 1.5 8.9 0.1 4.0 2 2 2 4 4 4 1 SLIDE DUF5591 PF17884.1 GAN01816.1 - 0.032 14.1 0.5 1.5 8.7 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5591) Nop16 PF09420.10 GAN01816.1 - 0.62 10.1 6.5 13 5.8 0.4 3.0 2 1 0 3 3 3 0 Ribosome biogenesis protein Nop16 Tox-GHH PF15636.6 GAN01816.1 - 3 7.9 14.0 1.6 8.8 1.4 4.4 5 0 0 5 5 5 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Ras PF00071.22 GAN01817.1 - 1e-31 109.7 0.0 2e-31 108.8 0.0 1.4 1 1 1 2 2 2 1 Ras family Roc PF08477.13 GAN01817.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN01817.1 - 0.039 13.4 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family LSM PF01423.22 GAN01818.1 - 1.4e-20 72.7 0.0 1.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain PUF PF00806.19 GAN01819.1 - 1e-54 179.2 14.9 2e-08 33.5 0.0 8.5 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat zf-CCCH PF00642.24 GAN01819.1 - 0.00051 19.9 1.7 0.0015 18.4 1.7 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CPL PF08144.11 GAN01819.1 - 0.0011 19.3 0.6 5.4 7.4 0.0 4.2 3 2 2 5 5 5 2 CPL (NUC119) domain TFIIA PF03153.13 GAN01819.1 - 0.026 14.5 27.3 0.11 12.5 5.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf_CCCH_4 PF18345.1 GAN01819.1 - 0.043 13.9 2.0 0.11 12.6 2.0 1.7 1 0 0 1 1 1 0 Zinc finger domain DUF4834 PF16118.5 GAN01819.1 - 0.1 13.5 18.2 0.18 12.8 4.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 GAN01819.1 - 0.24 11.0 35.7 1.6 8.3 15.2 2.7 2 0 0 2 2 2 0 Spt20 family EOS1 PF12326.8 GAN01819.1 - 0.3 11.0 1.0 20 5.1 0.1 2.3 2 0 0 2 2 2 0 N-glycosylation protein Neur_chan_memb PF02932.16 GAN01819.1 - 0.86 9.6 6.5 1.8 8.5 0.9 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 GAN01819.1 - 1.1 8.1 29.1 0.14 11.1 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SopA PF13981.6 GAN01820.1 - 0.059 13.8 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 SopA-like central domain Cwf_Cwc_15 PF04889.12 GAN01820.1 - 1.1 8.9 6.3 1.4 8.6 6.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 GAN01820.1 - 3.8 7.6 5.3 4.3 7.4 5.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PAP2 PF01569.21 GAN01822.1 - 3.5e-15 56.0 8.4 3.5e-15 56.0 8.4 2.7 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 GAN01822.1 - 0.0013 18.8 0.2 0.25 11.5 0.0 2.5 1 1 1 2 2 2 2 Divergent PAP2 family UPF0014 PF03649.13 GAN01822.1 - 0.016 14.6 3.6 0.027 13.8 1.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) DUF1430 PF07242.11 GAN01822.1 - 0.2 11.9 6.0 4.7 7.5 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) Transmemb_17 PF09799.9 GAN01822.1 - 0.68 10.5 7.7 0.12 12.9 2.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein EI24 PF07264.11 GAN01823.1 - 6.6e-25 88.4 24.7 8.4e-25 88.0 24.7 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TRAP-gamma PF07074.12 GAN01823.1 - 1.2 8.7 4.1 1.5 8.4 3.1 1.7 1 1 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Tetraspanin PF00335.20 GAN01824.1 - 1e-16 61.4 7.9 1.4e-16 61.0 7.9 1.2 1 0 0 1 1 1 1 Tetraspanin family RIC3 PF15361.6 GAN01824.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 TRP PF06011.12 GAN01824.1 - 0.91 8.2 6.7 0.24 10.1 2.5 1.8 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel ABC_membrane PF00664.23 GAN01825.1 - 1.6e-47 162.5 32.0 1.4e-30 106.9 13.2 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN01825.1 - 2.8e-45 154.2 0.3 2.6e-29 102.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter Ribosomal_L23eN PF03939.13 GAN01825.1 - 3.3e-22 78.4 6.0 6.5e-22 77.5 6.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GAN01825.1 - 2.2e-14 53.6 0.5 6.3e-14 52.1 0.5 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 SMC_N PF02463.19 GAN01825.1 - 6.4e-07 29.0 4.0 0.0074 15.7 2.5 3.8 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 GAN01825.1 - 4.3e-05 22.7 0.0 0.062 12.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 GAN01825.1 - 0.00037 20.2 1.5 0.59 9.9 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ResIII PF04851.15 GAN01825.1 - 0.0006 19.9 0.9 0.52 10.3 0.0 3.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAN01825.1 - 0.0015 18.8 0.1 1.4 9.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 GAN01825.1 - 0.0022 17.0 0.1 1.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 GAN01825.1 - 0.0034 17.5 0.6 0.21 11.6 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 GAN01825.1 - 0.0043 16.6 0.1 1.9 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAN01825.1 - 0.0044 17.4 0.3 2.2 8.6 0.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 GAN01825.1 - 0.0077 16.1 0.9 3.5 7.3 0.0 3.1 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 GAN01825.1 - 0.011 15.5 0.4 0.069 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAN01825.1 - 0.026 13.7 0.0 0.21 10.7 0.0 2.5 3 1 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.6 GAN01825.1 - 0.047 14.2 9.9 0.097 13.2 0.1 4.0 4 1 0 4 4 3 0 AAA domain DUF2075 PF09848.9 GAN01825.1 - 0.077 12.2 2.2 2.1 7.5 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Kri1_C PF12936.7 GAN01825.1 - 0.1 12.8 0.1 0.35 11.1 0.1 1.9 1 0 0 1 1 1 0 KRI1-like family C-terminal ATPase PF06745.13 GAN01825.1 - 0.25 10.7 4.8 2.5 7.4 0.0 3.0 4 0 0 4 4 4 0 KaiC FtsK_SpoIIIE PF01580.18 GAN01825.1 - 0.31 10.4 1.4 21 4.4 0.2 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pes-10 PF07149.11 GAN01825.1 - 0.44 9.5 5.6 0.18 10.9 0.1 2.4 2 0 0 2 2 2 0 Pes-10 Ribosomal_L7Ae PF01248.26 GAN01826.1 - 2.5e-28 97.7 2.1 3.1e-28 97.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1517 PF07466.11 GAN01826.1 - 0.045 13.9 0.2 0.049 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Ribosomal_S7e PF01251.18 GAN01827.1 - 1.2e-82 276.1 0.2 1.3e-82 276.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Sel1 PF08238.12 GAN01828.1 - 9.2e-110 356.6 54.6 5.6e-11 42.7 0.1 15.6 16 0 0 16 16 16 13 Sel1 repeat TPR_6 PF13174.6 GAN01828.1 - 0.0072 16.9 13.7 5.9 7.7 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat Fib_succ_major PF09603.10 GAN01828.1 - 0.083 13.5 8.0 6.8 7.3 0.7 4.1 1 1 2 4 4 4 0 Fibrobacter succinogenes major domain (Fib_succ_major) Neuromodulin_N PF10580.9 GAN01828.1 - 0.16 11.8 1.3 56 3.7 0.0 3.9 3 0 0 3 3 3 0 Gap junction protein N-terminal region TPR_7 PF13176.6 GAN01828.1 - 0.2 11.8 3.8 3.9 7.7 0.2 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 GAN01829.1 - 0.00037 21.1 2.2 0.042 14.7 0.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 GAN01829.1 - 0.067 13.3 1.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF1151 PF06625.11 GAN01829.1 - 0.082 12.9 0.4 0.98 9.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) zf-C2H2_2 PF12756.7 GAN01829.1 - 0.23 11.8 3.5 0.23 11.8 1.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.16 GAN01829.1 - 0.25 11.7 2.9 10 6.6 0.7 2.5 2 0 0 2 2 2 0 C1 domain zf-C2H2_6 PF13912.6 GAN01829.1 - 1.2 9.2 9.5 0.8 9.8 2.4 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-CCHC PF00098.23 GAN01830.1 - 4.6e-07 29.6 8.4 0.00058 19.8 1.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 GAN01830.1 - 0.0016 18.1 1.8 0.0016 18.1 1.8 2.4 3 0 0 3 3 3 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 GAN01830.1 - 0.02 14.6 6.2 0.23 11.2 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-nanos PF05741.13 GAN01830.1 - 0.029 14.6 5.7 0.12 12.6 5.7 2.0 1 1 0 1 1 1 0 Nanos RNA binding domain Exo_endo_phos_2 PF14529.6 GAN01831.1 - 0.00054 19.8 0.2 0.00093 19.0 0.2 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN01831.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF3208 PF11482.8 GAN01831.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) RVT_1 PF00078.27 GAN01832.1 - 4.1e-10 39.5 0.0 1.1e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ERG4_ERG24 PF01222.17 GAN01833.1 - 2.1e-138 461.7 18.2 2.4e-138 461.5 18.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family EF-hand_1 PF00036.32 GAN01834.1 - 1e-12 46.6 5.4 5.7e-06 25.5 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAN01834.1 - 2.1e-12 47.3 8.3 5.3e-12 46.0 7.5 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GAN01834.1 - 6.8e-10 38.0 2.5 4.7e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAN01834.1 - 2.5e-09 36.3 5.1 2.3e-05 24.0 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GAN01834.1 - 9.9e-06 25.3 7.0 0.0048 16.7 1.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAN01834.1 - 0.0045 17.3 4.8 0.57 10.5 0.7 2.9 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAN01834.1 - 0.27 11.2 6.0 3.3 7.7 0.8 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Ribosomal_L11 PF00298.19 GAN01835.1 - 2.2e-16 60.1 0.1 3.7e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAN01835.1 - 2e-10 40.3 0.3 4.4e-10 39.2 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain ADH_zinc_N PF00107.26 GAN01836.1 - 2.3e-27 95.5 0.1 4.5e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN01836.1 - 5.8e-18 66.2 0.0 1.4e-17 65.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN01836.1 - 1.4e-09 37.8 0.0 3.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAN01836.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Thr_dehydrat_C PF00585.18 GAN01836.1 - 0.097 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase zf-C2H2_4 PF13894.6 GAN01837.1 - 9.9e-06 26.0 14.9 0.008 16.9 2.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger DUF629 PF04780.12 GAN01837.1 - 0.0015 17.1 0.5 0.029 12.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF629) zf-BED PF02892.15 GAN01837.1 - 0.0053 16.8 1.5 2 8.5 0.0 3.3 3 0 0 3 3 3 1 BED zinc finger zf-met PF12874.7 GAN01837.1 - 0.0058 17.0 7.0 12 6.5 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 GAN01837.1 - 0.0069 17.1 1.3 0.89 10.2 0.0 2.6 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 GAN01837.1 - 0.0089 16.4 1.6 0.0089 16.4 1.6 2.7 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAN01837.1 - 0.016 15.5 11.6 0.36 11.2 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_2 PF03107.16 GAN01837.1 - 0.031 14.6 1.5 5.6 7.4 0.1 3.1 3 0 0 3 3 3 0 C1 domain zf-AD PF07776.15 GAN01837.1 - 0.072 13.3 0.2 0.072 13.3 0.2 2.7 3 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Zn-ribbon_8 PF09723.10 GAN01837.1 - 0.085 13.0 6.7 5.4 7.2 0.2 3.5 3 0 0 3 3 3 0 Zinc ribbon domain DUF3045 PF11243.8 GAN01837.1 - 0.11 12.6 0.6 0.25 11.5 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3045) zf_C2H2_ZHX PF18387.1 GAN01837.1 - 0.13 11.9 5.4 6.9 6.4 0.2 3.5 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 GAN01837.1 - 0.2 12.2 15.7 0.86 10.2 2.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pollen_Ole_e_I PF01190.17 GAN01837.1 - 0.21 12.0 3.6 1.2 9.6 0.4 2.4 2 0 0 2 2 2 0 Pollen proteins Ole e I like zinc_ribbon_15 PF17032.5 GAN01837.1 - 0.42 11.4 7.2 2.7 8.8 1.3 2.7 1 1 2 3 3 3 0 zinc-ribbon family zf-C2HE PF16278.5 GAN01837.1 - 0.42 11.1 7.5 2.6 8.6 4.0 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-FCS PF06467.14 GAN01837.1 - 1.5 8.9 7.4 0.81 9.7 0.2 3.1 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_6 PF13912.6 GAN01837.1 - 2.9 8.0 14.0 0.39 10.8 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_M24 PF00557.24 GAN01838.1 - 8.4e-60 202.0 0.1 1.1e-59 201.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAN01838.1 - 3e-25 88.4 0.0 6.3e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 GAN01838.1 - 0.029 14.4 0.1 0.074 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) TPR_1 PF00515.28 GAN01840.1 - 2.5e-51 169.5 39.5 6e-08 32.2 0.1 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAN01840.1 - 3.5e-46 151.6 33.5 2.6e-06 27.1 0.1 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAN01840.1 - 6.1e-33 110.3 30.1 4.5e-05 23.3 0.0 10.9 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 GAN01840.1 - 1.6e-27 93.9 26.2 0.00073 19.7 0.1 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAN01840.1 - 8.8e-26 90.3 14.2 1.2e-06 29.0 0.1 6.9 5 1 1 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAN01840.1 - 8.5e-25 87.1 20.3 6.3e-05 23.4 0.1 7.3 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAN01840.1 - 2.7e-24 83.8 14.3 0.00031 21.3 0.1 9.1 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAN01840.1 - 5.7e-24 84.2 25.4 2.5e-05 24.5 2.4 7.1 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAN01840.1 - 1.3e-19 69.6 42.9 8.9e-06 25.3 1.4 9.7 5 2 5 10 10 10 5 TPR repeat TPR_7 PF13176.6 GAN01840.1 - 1.4e-18 65.4 21.6 0.036 14.1 0.5 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.6 GAN01840.1 - 1.7e-17 62.8 27.6 0.0025 18.4 0.0 9.3 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAN01840.1 - 4.9e-17 61.8 14.0 0.00033 20.7 0.4 6.7 2 2 5 7 7 7 7 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN01840.1 - 1.1e-09 38.3 20.0 4.4e-06 26.8 5.0 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAN01840.1 - 3.3e-08 33.1 11.7 0.029 13.6 2.3 5.2 1 1 1 3 3 3 3 Tetratricopeptide repeat DUF2225 PF09986.9 GAN01840.1 - 0.00043 20.1 8.0 0.12 12.1 2.9 2.9 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.9 GAN01840.1 - 0.0085 15.8 14.2 0.65 9.7 0.0 4.9 5 1 0 5 5 4 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 GAN01840.1 - 0.0088 15.5 19.3 2.6 7.4 0.4 4.4 1 1 3 4 4 4 2 Soluble NSF attachment protein, SNAP TOM20_plant PF06552.12 GAN01840.1 - 0.72 9.6 5.7 35 4.1 0.2 4.5 3 2 2 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.6 GAN01840.1 - 0.75 10.2 10.5 4.2 7.8 0.1 5.5 3 2 3 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 GAN01840.1 - 1.1 9.6 13.8 3.7 8.0 0.5 3.9 4 0 0 4 4 4 0 Bacterial transcriptional activator domain ChAPs PF09295.10 GAN01840.1 - 1.5 7.8 10.6 1.3 7.9 0.4 4.0 3 1 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 GAN01840.1 - 5.9 7.1 29.5 5.6 7.1 0.4 7.3 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 GAN01840.1 - 6.6 6.8 20.7 7.1 6.7 0.7 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAN01840.1 - 8.1 6.5 27.3 31 4.6 0.2 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat Osteopontin PF00865.18 GAN01841.1 - 0.00082 19.0 23.2 0.0014 18.2 23.2 1.3 1 0 0 1 1 1 1 Osteopontin Nop14 PF04147.12 GAN01841.1 - 0.021 13.1 5.8 0.027 12.7 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family Macro PF01661.21 GAN01841.1 - 0.032 14.3 0.2 0.13 12.3 0.1 2.1 2 1 1 3 3 3 0 Macro domain DUF3819 PF12842.7 GAN01841.1 - 0.059 13.3 13.9 21 5.0 0.1 5.8 5 1 2 7 7 7 0 Domain of unknown function (DUF3819) DUF5102 PF17104.5 GAN01841.1 - 0.56 10.2 6.2 0.43 10.6 4.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) RRN3 PF05327.11 GAN01841.1 - 0.7 8.4 6.4 1.1 7.8 6.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 GAN01841.1 - 0.93 8.8 11.2 1.4 8.2 11.2 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAN01841.1 - 2.5 6.3 7.4 3.6 5.8 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein UPF0176_N PF17773.1 GAN01842.1 - 3.1e-17 62.7 0.0 6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAN01842.1 - 2.4e-15 56.6 14.3 2.4e-15 56.6 14.3 2.0 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 GAN01842.1 - 1.7e-07 31.7 0.0 4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_L6 PF00347.23 GAN01843.1 - 7.3e-29 100.3 7.5 1.4e-17 64.1 3.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.12 GAN01843.1 - 0.0095 16.3 0.6 1.9 8.9 0.1 2.5 2 0 0 2 2 2 2 YbbR-like protein HSP70 PF00012.20 GAN01844.1 - 9.3e-07 27.4 0.0 3.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.20 GAN01844.1 - 0.1 12.1 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PPC PF04151.15 GAN01844.1 - 0.4 11.8 3.0 2 9.6 0.0 3.4 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain UQ_con PF00179.26 GAN01845.1 - 1e-19 70.6 0.1 1.6e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN01845.1 - 0.0031 17.8 0.3 0.0086 16.4 0.2 1.6 1 1 0 1 1 1 1 RWD domain Importin_rep PF18773.1 GAN01845.1 - 0.07 12.8 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Importin 13 repeat UFC1 PF08694.11 GAN01845.1 - 0.072 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UCH PF00443.29 GAN01846.1 - 4.8e-12 45.9 0.0 1.4e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 GAN01846.1 - 0.0018 18.2 0.1 0.0048 16.8 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Polysacc_deac_1 PF01522.21 GAN01847.1 - 2.7e-11 43.4 0.1 9.6e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase TFIIE-A_C PF11521.8 GAN01847.1 - 2.3 8.6 8.5 2.1 8.7 6.3 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha WD40 PF00400.32 GAN01848.1 - 1.5e-17 63.6 12.7 1.1e-05 26.0 0.3 6.4 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN01848.1 - 2.6e-10 40.5 0.0 0.0018 18.5 0.0 4.8 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN01848.1 - 0.00016 21.1 0.0 0.00072 19.0 0.0 1.9 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 GAN01848.1 - 0.072 11.7 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN01848.1 - 0.11 11.4 0.2 17 4.2 0.0 3.0 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GFO_IDH_MocA PF01408.22 GAN01849.1 - 1.9e-25 90.0 0.0 4.4e-25 88.8 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAN01849.1 - 4.9e-15 55.6 0.0 8.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 GAN01849.1 - 0.0011 19.5 0.0 0.0023 18.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 GAN01849.1 - 0.0036 17.7 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 GAN01849.1 - 0.0056 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain PET117 PF15786.5 GAN01851.1 - 0.14 12.5 5.9 0.15 12.3 5.9 1.1 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial ArfGap PF01412.18 GAN01852.1 - 1.3e-41 141.4 0.9 1.3e-41 141.4 0.9 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Nop53 PF07767.11 GAN01852.1 - 3.5 6.9 9.2 1 8.6 6.4 1.5 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) IF-2B PF01008.17 GAN01853.1 - 6.5e-73 245.4 0.9 8.7e-73 245.0 0.9 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Med14 PF08638.11 GAN01853.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit MED14 SQS_PSY PF00494.19 GAN01854.1 - 3.7e-37 128.2 0.0 6e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase TctB PF07331.11 GAN01854.1 - 0.16 12.3 6.6 0.54 10.5 6.6 1.9 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4625 PF15418.6 GAN01856.1 - 0.024 14.9 0.1 0.038 14.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) DUF3284 PF11687.8 GAN01856.1 - 0.034 14.0 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) PhrC_PhrF PF11131.8 GAN01856.1 - 0.13 11.8 2.3 0.32 10.6 0.1 2.6 2 0 0 2 2 2 0 Rap-phr extracellular signalling Acetyltransf_10 PF13673.7 GAN01857.1 - 8.3e-11 41.9 0.0 1.2e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN01857.1 - 1.2e-10 41.6 0.0 1.6e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN01857.1 - 3.2e-09 37.1 0.0 5.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 GAN01857.1 - 0.001 19.7 0.1 0.037 14.7 0.0 2.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN01857.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 GAN01857.1 - 0.061 13.4 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAN01857.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Methyltr_RsmB-F PF01189.17 GAN01858.1 - 1.2e-28 100.2 0.0 4.5e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 GAN01858.1 - 4.6e-05 24.0 0.2 0.00047 20.8 0.0 2.8 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN01858.1 - 0.00087 19.1 0.1 0.098 12.4 0.1 2.6 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.19 GAN01858.1 - 0.011 15.9 0.0 0.037 14.1 0.0 2.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 GAN01858.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 GAN01858.1 - 0.065 13.9 0.0 1 10.1 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Polyketide_cyc2 PF10604.9 GAN01859.1 - 0.00026 21.3 0.6 0.00051 20.3 0.6 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAN01859.1 - 0.00045 20.4 0.3 0.00082 19.6 0.3 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MoCF_biosynth PF00994.24 GAN01860.1 - 1.1e-61 206.7 1.4 5.4e-31 107.2 0.1 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 GAN01860.1 - 1.8e-33 115.5 0.9 1.8e-33 115.5 0.9 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 GAN01860.1 - 7.3e-14 51.7 0.0 2.1e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) tRNA-synt_1 PF00133.22 GAN01862.1 - 1.2e-61 208.7 0.1 7.1e-21 74.1 1.0 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 GAN01862.1 - 1.4e-56 190.9 0.0 2.8e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 GAN01862.1 - 8.3e-29 100.5 2.3 8.4e-20 70.9 0.0 4.4 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAN01862.1 - 1e-19 71.0 0.2 2.1e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Spt20 PF12090.8 GAN01862.1 - 0.062 12.9 5.5 0.11 12.1 5.5 1.3 1 0 0 1 1 1 0 Spt20 family tRNA-synt_1e PF01406.19 GAN01862.1 - 0.067 12.5 2.4 0.43 9.9 0.1 2.8 2 1 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF2281 PF10047.9 GAN01862.1 - 0.092 13.5 0.2 0.28 11.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Ldh_1_N PF00056.23 GAN01864.1 - 9.5e-33 113.3 0.9 1.5e-32 112.6 0.9 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GAN01864.1 - 9.8e-22 77.7 0.0 2.1e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 GAN01864.1 - 0.0021 17.7 1.0 0.021 14.4 1.0 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAN01864.1 - 0.0038 17.1 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAN01864.1 - 0.0044 16.7 0.5 0.019 14.6 0.5 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 GAN01864.1 - 0.013 15.1 2.5 0.021 14.4 0.8 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN01864.1 - 0.013 14.7 0.3 0.029 13.6 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAN01864.1 - 0.018 15.3 0.6 0.033 14.5 0.6 1.6 1 1 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 GAN01864.1 - 0.019 15.5 1.1 0.052 14.1 0.8 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 GAN01864.1 - 0.022 14.1 0.9 0.032 13.5 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAN01864.1 - 0.024 15.2 0.1 0.067 13.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 GAN01864.1 - 0.025 13.9 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 GAN01864.1 - 0.037 14.1 0.3 0.064 13.3 0.3 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 GAN01864.1 - 0.07 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 GAN01864.1 - 0.092 13.2 0.2 0.2 12.1 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_25 PF13649.6 GAN01864.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SAMP PF05924.11 GAN01865.1 - 0.094 12.0 1.8 0.21 10.9 1.8 1.6 1 0 0 1 1 1 0 SAMP Motif EGF_CA PF07645.15 GAN01865.1 - 0.43 10.8 4.9 0.85 9.9 4.9 1.6 1 1 0 1 1 1 0 Calcium-binding EGF domain TMEM252 PF15664.5 GAN01866.1 - 0.053 13.2 0.2 0.098 12.4 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family Herpes_DNAp_acc PF04929.12 GAN01866.1 - 0.78 8.7 5.8 1.1 8.2 5.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Defensin_propep PF00879.18 GAN01867.1 - 0.33 11.3 5.0 0.53 10.6 5.0 1.3 1 0 0 1 1 1 0 Defensin propeptide Polysacc_deac_1 PF01522.21 GAN01868.1 - 6.1e-29 100.4 0.2 1.6e-28 99.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN01868.1 - 3.3e-05 23.3 0.1 0.00035 19.9 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 Dioxygenase_N PF04444.14 GAN01868.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Sacchrp_dh_C PF16653.5 GAN01868.1 - 0.098 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain Polysacc_deac_1 PF01522.21 GAN01869.1 - 9.8e-28 96.5 0.0 2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN01869.1 - 2.4e-08 33.6 0.2 7e-08 32.0 0.1 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 GAN01869.1 - 1.1e-05 25.2 0.2 1.5e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Pkinase PF00069.25 GAN01870.1 - 2.9e-54 184.2 0.0 4.6e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01870.1 - 2.1e-20 73.1 0.0 4.1e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 GAN01870.1 - 2.3e-08 34.0 0.0 0.025 14.6 0.0 3.8 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 GAN01870.1 - 3e-08 33.8 0.0 0.017 15.4 0.0 4.4 3 1 0 3 3 3 2 PAS domain Kinase-like PF14531.6 GAN01870.1 - 3.5e-05 23.3 0.0 0.00012 21.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN01870.1 - 4.4e-05 22.6 0.9 9.5e-05 21.5 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 GAN01870.1 - 0.00043 19.9 0.4 0.00081 19.0 0.4 1.4 1 0 0 1 1 1 1 RIO1 family PAS_4 PF08448.10 GAN01870.1 - 0.00096 19.4 0.0 4 7.7 0.0 3.4 3 0 0 3 3 3 1 PAS fold Kdo PF06293.14 GAN01870.1 - 0.0014 18.0 0.4 0.0025 17.2 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN01870.1 - 0.0033 17.4 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAN01870.1 - 0.031 13.3 2.5 0.056 12.5 2.5 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAN01870.1 - 0.039 12.7 0.0 0.082 11.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Citrate_ly_lig PF08218.11 GAN01870.1 - 0.14 11.9 0.0 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain HCMVantigenic_N PF12154.8 GAN01870.1 - 2.9 8.1 7.9 9.1 6.5 7.9 1.9 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Arrestin_C PF02752.22 GAN01871.1 - 7.7e-18 65.2 0.4 2.4e-15 57.2 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN01871.1 - 3.9e-08 33.5 0.1 2.6e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN01871.1 - 0.0024 17.6 0.0 0.0077 16.0 0.0 1.9 1 1 0 1 1 1 1 Arrestin_N terminal like Glutaredoxin2_C PF04399.13 GAN01871.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain zf-C3HC4 PF00097.25 GAN01872.1 - 3.6e-09 36.3 9.1 5.7e-09 35.7 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN01872.1 - 4.2e-09 36.6 10.7 6.8e-09 35.9 10.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAN01872.1 - 1e-08 34.9 7.2 1.5e-08 34.3 7.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN01872.1 - 3.4e-08 33.2 8.1 5.4e-08 32.5 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN01872.1 - 2.7e-06 27.3 8.8 1.4e-05 25.0 4.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAN01872.1 - 3.6e-05 23.5 7.6 6.7e-05 22.7 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAN01872.1 - 7.6e-05 22.6 9.4 0.00012 21.9 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAN01872.1 - 0.00046 20.4 9.6 0.0016 18.7 9.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAN01872.1 - 0.0005 20.1 4.1 0.001 19.0 4.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAN01872.1 - 0.016 15.0 6.5 0.029 14.2 6.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAN01872.1 - 0.047 13.9 8.1 0.14 12.3 8.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 GAN01872.1 - 0.048 13.6 6.3 0.049 13.6 4.6 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Siva PF05458.12 GAN01872.1 - 0.14 11.8 1.2 0.22 11.2 1.2 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) RINGv PF12906.7 GAN01872.1 - 1.6 8.9 6.4 2.4 8.4 4.1 2.4 2 1 0 2 2 2 0 RING-variant domain zf-RING_11 PF17123.5 GAN01872.1 - 2.3 8.1 11.0 0.28 11.0 5.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_5 PF17121.5 GAN01872.1 - 8.3 6.4 8.9 1.1e+02 2.8 9.6 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SAP30_Sin3_bdg PF13867.6 GAN01873.1 - 2.9e-18 66.0 0.3 4.7e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ish1 PF10281.9 GAN01873.1 - 0.002 18.4 0.0 0.002 18.4 0.0 1.9 3 0 0 3 3 3 1 Putative stress-responsive nuclear envelope protein Med3 PF11593.8 GAN01873.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF5525 PF17663.1 GAN01873.1 - 0.13 10.4 0.4 0.14 10.2 0.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Tir_receptor_C PF07489.11 GAN01873.1 - 0.13 12.2 0.6 0.15 12.0 0.6 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DnaJ PF00226.31 GAN01874.1 - 1.3e-28 98.9 2.8 2.1e-28 98.2 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain Inhibitor_Mig-6 PF11555.8 GAN01874.1 - 0.098 12.8 0.8 6.8 6.9 0.0 2.7 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Chitin_synth_2 PF03142.15 GAN01875.1 - 5.6e-240 797.4 2.3 7.9e-240 796.9 2.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAN01875.1 - 1.4e-150 502.7 1.5 2.7e-150 501.8 1.5 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 GAN01875.1 - 7.5e-18 64.5 0.1 7.5e-14 51.6 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAN01875.1 - 1e-12 48.4 0.9 1e-12 48.4 0.9 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAN01875.1 - 6.2e-12 45.9 0.0 9.4e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAN01875.1 - 0.00078 19.3 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.6 GAN01875.1 - 0.0038 17.6 0.0 0.02 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAN01875.1 - 0.0059 16.9 0.1 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Glyco_transf_21 PF13506.6 GAN01875.1 - 0.0098 15.4 0.0 0.035 13.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_7 PF12775.7 GAN01875.1 - 0.063 12.8 0.3 0.14 11.6 0.3 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region WBS_methylT PF12589.8 GAN01876.1 - 1.4e-22 80.2 7.7 2.2e-22 79.6 7.7 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 GAN01876.1 - 2.3e-11 44.2 0.0 3.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN01876.1 - 1.4e-09 38.5 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN01876.1 - 4.4e-06 27.4 0.1 1.1e-05 26.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN01876.1 - 8.9e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN01876.1 - 0.00028 20.7 0.0 0.00058 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAN01876.1 - 0.0063 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 GAN01876.1 - 0.0074 16.6 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 GAN01876.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 GAN01876.1 - 0.041 13.9 0.1 0.089 12.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_S13 PF00416.22 GAN01877.1 - 7.3e-20 71.7 0.6 4.6e-18 65.8 0.6 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAN01877.1 - 0.018 13.9 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) TPP_enzyme_N PF02776.18 GAN01878.1 - 1.1e-30 106.5 0.0 1.7e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAN01878.1 - 4.1e-20 71.9 0.0 7.8e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAN01878.1 - 5.8e-16 58.6 0.0 1.9e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1_like PF12832.7 GAN01878.1 - 0.058 12.2 0.3 0.09 11.6 0.3 1.2 1 0 0 1 1 1 0 MFS_1 like family p450 PF00067.22 GAN01879.1 - 3.1e-76 257.0 0.0 3.7e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UCH PF00443.29 GAN01880.1 - 2.3e-57 194.4 1.5 3.8e-57 193.7 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN01880.1 - 4.4e-19 69.2 9.1 4.4e-19 69.2 9.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAN01880.1 - 1e-14 54.5 9.7 1e-14 54.5 9.7 3.5 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein zf_UBZ PF18439.1 GAN01880.1 - 0.054 13.1 6.3 2.6 7.7 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 GAN01880.1 - 3.4 8.3 10.9 9.1 6.9 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger double domain SWIB PF02201.18 GAN01882.1 - 5.6e-23 80.6 0.1 5.6e-23 80.6 0.1 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain Fasciclin PF02469.22 GAN01883.1 - 1.6e-16 60.7 0.4 2e-16 60.4 0.4 1.1 1 0 0 1 1 1 1 Fasciclin domain STE PF02200.16 GAN01884.1 - 3e-55 185.3 0.1 5.3e-55 184.5 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 GAN01884.1 - 6e-10 39.0 11.4 0.00014 22.1 1.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN01884.1 - 1.8e-08 34.5 8.3 0.00086 20.0 0.8 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN01884.1 - 1.9e-05 24.9 2.2 1.9e-05 24.9 2.2 4.2 5 0 0 5 5 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAN01884.1 - 5.9e-05 23.0 1.3 5.9e-05 23.0 1.3 3.2 3 0 0 3 3 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN01884.1 - 0.00074 19.7 3.0 0.11 12.9 0.4 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 GAN01884.1 - 0.0011 19.6 12.4 0.0011 19.6 12.4 2.5 2 0 0 2 2 1 1 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 GAN01884.1 - 0.07 12.5 11.6 0.14 11.5 11.6 1.4 1 0 0 1 1 1 0 NOA36 protein PGA2 PF07543.12 GAN01884.1 - 0.079 12.9 5.9 0.31 11.0 5.9 2.0 1 0 0 1 1 1 0 Protein trafficking PGA2 RNA_pol_3_Rpc31 PF11705.8 GAN01884.1 - 0.86 9.8 28.9 8.5 6.6 28.9 2.3 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 GAN01884.1 - 1.9 8.9 14.9 1e+02 3.4 17.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PPR_3 PF13812.6 GAN01885.1 - 4e-43 145.3 9.4 1.3e-11 44.4 0.3 6.7 5 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAN01885.1 - 7.3e-33 112.5 9.3 1.2e-05 25.4 0.1 8.2 3 2 5 8 8 8 8 PPR repeat family PPR_long PF17177.4 GAN01885.1 - 1.2e-27 96.7 10.1 9.6e-09 34.9 4.2 4.6 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAN01885.1 - 6.2e-14 51.2 14.2 0.033 14.4 0.2 9.4 12 0 0 12 12 12 4 PPR repeat PPR_1 PF12854.7 GAN01885.1 - 2e-08 33.8 5.8 0.27 11.0 0.0 6.2 5 0 0 5 5 5 4 PPR repeat ECSIT PF06239.11 GAN01885.1 - 0.0033 16.6 2.6 3.2 6.8 0.0 4.2 2 2 1 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway T4BSS_DotI_IcmL PF11393.8 GAN01885.1 - 0.03 13.8 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component ATPase PF06745.13 GAN01885.1 - 0.058 12.7 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 KaiC YodL PF14191.6 GAN01885.1 - 0.18 12.7 4.0 16 6.4 0.1 4.6 2 2 2 5 5 5 0 YodL-like MFS_1 PF07690.16 GAN01886.1 - 8.6e-39 133.5 35.6 1.2e-38 132.9 35.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 GAN01887.1 - 9e-21 74.4 0.0 2e-20 73.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAN01887.1 - 6.2e-06 25.2 0.0 8.5e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GAN01887.1 - 0.00035 20.0 0.0 0.0015 17.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APG6_N PF17675.1 GAN01888.1 - 0.57 10.7 31.1 0.022 15.3 17.6 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 GAN01888.1 - 1.7 7.5 35.3 0.07 12.0 10.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 GAN01888.1 - 4.7 7.2 33.1 0.21 11.6 1.3 3.6 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRANC PF09372.10 GAN01888.1 - 7.4 7.0 9.2 0.66 10.3 0.9 3.1 2 2 2 4 4 4 0 PRANC domain UPF0014 PF03649.13 GAN01890.1 - 2.9e-48 164.3 17.7 4.6e-48 163.7 17.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) CDC45 PF02724.14 GAN01890.1 - 8e-06 24.4 11.2 1.3e-05 23.8 11.2 1.3 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GAN01890.1 - 1.1e-05 25.0 16.2 1.9e-05 24.3 16.2 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAN01890.1 - 2.9e-05 22.5 19.1 4.1e-05 22.0 19.1 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 GAN01890.1 - 3.1e-05 24.2 12.4 4.6e-05 23.7 12.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein PPP4R2 PF09184.11 GAN01890.1 - 0.42 10.1 25.9 0.026 14.1 20.6 1.6 2 0 0 2 2 2 0 PPP4R2 Mpp10 PF04006.12 GAN01890.1 - 0.8 8.1 28.2 1.2 7.5 28.2 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GAN01890.1 - 2.1 7.0 11.9 3.4 6.3 11.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YjeF_N PF03853.15 GAN01891.1 - 1.2e-31 109.9 0.1 2.2e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 GAN01891.1 - 5.4e-06 27.2 9.3 5.4e-06 27.2 9.3 2.8 2 1 1 3 3 3 1 FDF domain LSM14 PF12701.7 GAN01891.1 - 0.0002 21.4 0.1 0.00081 19.4 0.1 2.0 1 1 0 1 1 1 1 Scd6-like Sm domain CDC45 PF02724.14 GAN01891.1 - 0.048 11.9 5.0 0.083 11.2 5.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAN01891.1 - 0.66 8.1 15.2 0.89 7.7 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAN01891.1 - 2.1 7.7 15.7 3.4 7.0 15.7 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GAN01891.1 - 3.6 5.6 14.3 6.5 4.7 14.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi HLH PF00010.26 GAN01892.1 - 2.7e-08 33.6 1.7 2.7e-08 33.6 1.7 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2852 PF11014.8 GAN01892.1 - 4 7.6 5.7 1.4 9.1 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Homeodomain PF00046.29 GAN01893.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain THOC2_N PF16134.5 GAN01894.1 - 6.3e-101 339.0 3.3 1.4e-100 337.8 3.3 1.5 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 GAN01894.1 - 2.3e-77 260.2 7.4 2.3e-77 260.2 7.4 2.0 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 GAN01894.1 - 2.7e-23 81.8 0.1 3.4e-22 78.3 0.0 2.8 3 0 0 3 3 3 1 Transcription- and export-related complex subunit MIT_C PF16565.5 GAN01894.1 - 1.3 9.0 3.5 7.9 6.5 0.7 2.9 3 0 0 3 3 3 0 Phospholipase D-like domain at C-terminus of MIT MA3 PF02847.17 GAN01896.1 - 5.3e-29 100.5 0.2 1.3e-28 99.3 0.2 1.7 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 GAN01896.1 - 9.4e-10 38.5 1.4 1.8e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 MIF4G domain DUF5523 PF17661.1 GAN01896.1 - 0.005 16.5 5.6 0.012 15.3 5.6 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Ribosomal_L21e PF01157.18 GAN01897.1 - 1e-48 163.3 4.3 1.5e-48 162.8 4.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e S4 PF01479.25 GAN01898.1 - 4.3e-12 45.5 1.2 4.3e-12 45.5 1.2 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 GAN01898.1 - 0.00017 22.4 0.0 0.0003 21.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Fz PF01392.22 GAN01899.1 - 2e-07 31.6 2.3 3.9e-07 30.7 2.3 1.5 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.24 GAN01899.1 - 1.4e-05 24.5 13.5 2.2e-05 23.9 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Birna_RdRp PF04197.12 GAN01899.1 - 0.21 9.9 0.0 0.3 9.4 0.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) KH_1 PF00013.29 GAN01900.1 - 6.2e-49 163.7 4.7 5e-18 64.7 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAN01900.1 - 3.1e-13 49.3 3.8 0.0011 18.7 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAN01900.1 - 8.6e-10 38.4 6.8 0.00025 20.9 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAN01900.1 - 0.0021 18.1 7.4 0.43 10.7 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Cortexin PF11057.8 GAN01900.1 - 0.073 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Cortexin of kidney DUF3208 PF11482.8 GAN01900.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) SDH_sah PF01972.16 GAN01900.1 - 0.22 10.5 1.4 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Serine dehydrogenase proteinase DUF3292 PF11696.8 GAN01900.1 - 0.38 9.1 3.9 0.77 8.1 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) LysM PF01476.20 GAN01901.1 - 2.8e-10 40.1 0.1 0.00014 21.9 0.0 2.8 3 0 0 3 3 3 2 LysM domain Ndc1_Nup PF09531.10 GAN01901.1 - 0.2 10.3 11.9 0.27 9.9 11.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 GAN01901.1 - 0.26 10.9 47.3 0.36 10.4 47.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Macoilin PF09726.9 GAN01901.1 - 1.7 7.1 18.8 2.2 6.7 18.8 1.1 1 0 0 1 1 1 0 Macoilin family SOBP PF15279.6 GAN01901.1 - 2.2 8.8 16.4 3.2 8.3 16.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF936 PF06075.12 GAN01901.1 - 8.6 5.1 25.1 11 4.7 25.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FSA_C PF10479.9 GAN01901.1 - 8.8 4.3 28.3 17 3.4 28.3 1.6 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Lactamase_B_2 PF12706.7 GAN01902.1 - 6.2e-27 94.4 0.3 1.1e-26 93.6 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAN01902.1 - 5.3e-14 52.4 0.6 2.4e-13 50.3 0.1 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAN01902.1 - 0.018 15.1 0.3 0.1 12.6 0.3 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily LZ3wCH PF18517.1 GAN01903.1 - 9.7e-19 67.2 1.8 9.7e-19 67.2 1.8 2.5 3 0 0 3 3 3 1 Leucine zipper with capping helix domain Mnd1 PF03962.15 GAN01903.1 - 1.5e-08 34.8 0.0 1.5e-08 34.8 0.0 3.1 3 1 1 4 4 4 1 Mnd1 HTH domain TANGO2 PF05742.12 GAN01903.1 - 0.047 13.7 2.8 0.049 13.7 2.8 1.1 1 0 0 1 1 1 0 Transport and Golgi organisation 2 HAUS6_N PF14661.6 GAN01903.1 - 0.1 12.2 12.0 0.13 11.8 12.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.15 GAN01903.1 - 0.15 11.6 6.8 0.18 11.4 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 GAN01903.1 - 0.26 10.3 11.8 0.31 10.1 11.8 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3810 PF12725.7 GAN01903.1 - 0.3 10.4 2.8 0.35 10.2 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_S46 PF10459.9 GAN01903.1 - 0.47 9.0 9.9 0.56 8.8 9.9 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF4407 PF14362.6 GAN01903.1 - 0.54 9.6 9.9 0.64 9.3 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 GAN01903.1 - 0.55 8.8 8.0 0.7 8.4 8.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Bud13 PF09736.9 GAN01903.1 - 0.82 10.1 12.4 1.1 9.6 12.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PepSY_TM_like_2 PF16357.5 GAN01903.1 - 1.6 8.6 5.9 2 8.4 5.9 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like FAM178 PF14816.6 GAN01903.1 - 1.7 7.5 8.8 2.2 7.2 8.8 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 FUSC PF04632.12 GAN01903.1 - 1.8 7.0 2.6 2 6.8 2.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family KAsynt_C_assoc PF16197.5 GAN01903.1 - 3.4 8.2 4.7 8.3 6.9 3.3 2.1 1 1 1 2 2 2 0 Ketoacyl-synthetase C-terminal extension Presenilin PF01080.17 GAN01903.1 - 4.2 6.0 6.1 4.3 6.0 6.1 1.0 1 0 0 1 1 1 0 Presenilin VIT1 PF01988.19 GAN01903.1 - 4.4 7.1 5.8 5.9 6.7 5.8 1.1 1 0 0 1 1 1 0 VIT family Rnk_N PF14760.6 GAN01903.1 - 6 7.4 7.9 2.3 8.8 4.0 2.0 1 1 1 2 2 2 0 Rnk N-terminus RecQ_Zn_bind PF16124.5 GAN01903.1 - 7.4 7.4 6.2 3.1e+02 2.2 6.2 2.8 1 1 0 1 1 1 0 RecQ zinc-binding AAA PF00004.29 GAN01904.1 - 2.2e-17 63.7 0.0 5.4e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAN01904.1 - 2.3e-15 56.8 0.0 3.5e-14 52.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 GAN01904.1 - 7.8e-14 51.9 0.6 1.6e-13 50.9 0.6 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 GAN01904.1 - 6.5e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 GAN01904.1 - 2.3e-06 27.6 0.0 6.1e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAN01904.1 - 1.5e-05 24.8 0.0 5.4e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAN01904.1 - 1.9e-05 24.9 0.0 0.00077 19.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN01904.1 - 0.00016 22.1 0.0 0.0023 18.3 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAN01904.1 - 0.00022 21.2 0.0 0.00072 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAN01904.1 - 0.00024 21.2 0.0 0.0014 18.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 GAN01904.1 - 0.00024 20.9 0.0 0.00068 19.5 0.0 1.7 2 0 0 2 2 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 GAN01904.1 - 0.00025 20.5 0.0 0.014 14.8 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 GAN01904.1 - 0.00054 20.0 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAN01904.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAN01904.1 - 0.002 17.3 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAN01904.1 - 0.0028 18.0 0.4 0.019 15.4 0.0 2.5 3 1 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 GAN01904.1 - 0.0036 17.0 0.0 0.0094 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN01904.1 - 0.006 16.9 0.0 0.033 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAN01904.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 GAN01904.1 - 0.013 14.7 0.0 0.036 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_assoc_2 PF16193.5 GAN01904.1 - 0.014 15.7 0.0 0.045 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_23 PF13476.6 GAN01904.1 - 0.043 14.3 0.0 0.098 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAN01904.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAN01904.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 GAN01904.1 - 0.075 12.9 0.0 0.3 10.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAN01904.1 - 0.1 12.3 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase Ntox1 PF15500.6 GAN01904.1 - 0.14 12.6 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 1 0 Putative RNase-like toxin, toxin_1 AAA_18 PF13238.6 GAN01904.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 GAN01904.1 - 2.1 8.5 7.5 4.8 7.4 0.4 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-C2H2_jaz PF12171.8 GAN01905.1 - 4.7e-05 23.6 1.7 0.78 10.1 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAN01905.1 - 0.00077 19.8 6.2 0.33 11.5 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 GAN01905.1 - 0.0008 19.7 0.1 1.5 9.3 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN01905.1 - 0.0035 18.1 6.8 4 8.5 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger MSV199 PF10553.9 GAN01905.1 - 0.0087 16.3 0.1 0.027 14.7 0.0 1.8 2 0 0 2 2 2 1 MSV199 domain NMD3 PF04981.13 GAN01905.1 - 0.013 14.9 0.8 0.021 14.3 0.8 1.4 1 0 0 1 1 1 0 NMD3 family zf-H2C2_2 PF13465.6 GAN01905.1 - 0.45 11.0 0.1 0.45 11.0 0.1 3.3 4 0 0 4 4 4 0 Zinc-finger double domain F-box-like PF12937.7 GAN01907.1 - 3.1e-09 36.6 0.3 1e-08 34.9 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN01907.1 - 0.00065 19.5 0.1 0.00065 19.5 0.1 2.8 3 0 0 3 3 3 1 F-box domain DUF5066 PF16728.5 GAN01907.1 - 0.068 12.5 0.2 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5066) LRR_9 PF14580.6 GAN01907.1 - 0.16 11.5 1.1 0.81 9.2 0.3 2.5 2 1 0 2 2 2 0 Leucine-rich repeat LRR_4 PF12799.7 GAN01907.1 - 0.61 10.6 12.7 7.2 7.2 0.3 5.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) HMG-CoA_red PF00368.18 GAN01908.1 - 8e-145 482.5 6.3 1.3e-144 481.7 6.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 GAN01908.1 - 2.7e-18 66.3 4.2 6.3e-18 65.1 4.2 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAN01908.1 - 1.3e-09 36.8 11.3 3.2e-09 35.5 11.3 1.6 1 1 0 1 1 1 1 Patched family HPIH PF13323.6 GAN01908.1 - 0.03 14.2 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain with HPIH motif BRCT PF00533.26 GAN01909.1 - 2.6e-10 40.5 0.0 5e-09 36.4 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAN01909.1 - 3.5e-05 24.1 0.0 0.00015 22.1 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAN01909.1 - 0.00034 20.5 0.1 0.00072 19.4 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain SPT16 PF08644.11 GAN01910.1 - 1.3e-54 184.5 0.0 1.3e-54 184.5 0.0 3.2 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 GAN01910.1 - 1.8e-43 148.2 0.2 4.2e-43 146.9 0.2 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 GAN01910.1 - 9.6e-32 110.4 0.0 1.6e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GAN01910.1 - 8.9e-16 58.1 0.0 2.5e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like TUSC2 PF15000.6 GAN01910.1 - 0.19 12.0 3.6 0.21 11.9 0.4 2.8 2 0 0 2 2 2 0 Tumour suppressor candidate 2 ANAPC4_WD40 PF12894.7 GAN01911.1 - 0.0059 16.9 0.0 1.4 9.2 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN01911.1 - 1.4 9.9 4.7 36 5.4 0.2 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Helicase_C_2 PF13307.6 GAN01912.1 - 2.7e-55 187.2 0.0 8.6e-55 185.5 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAN01912.1 - 5.7e-52 175.9 0.5 1.2e-51 174.9 0.5 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 GAN01912.1 - 3.6e-05 23.8 1.6 0.024 14.6 0.0 3.1 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAN01912.1 - 0.0063 16.8 0.0 0.37 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GAN01912.1 - 0.074 12.5 0.7 5.6 6.4 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein Pinin_SDK_memA PF04696.13 GAN01912.1 - 9 6.4 26.1 0.079 13.0 16.2 2.4 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region E1-E2_ATPase PF00122.20 GAN01913.1 - 2.6e-27 95.5 0.0 9.4e-27 93.7 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAN01913.1 - 6e-08 33.2 0.4 0.00032 21.1 0.2 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN01913.1 - 0.00029 20.9 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN01913.1 - 0.00073 19.2 0.0 0.00073 19.2 0.0 3.0 5 0 0 5 5 5 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN01913.1 - 0.032 14.0 0.2 0.3 10.8 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 GAN01914.1 - 0.0098 16.0 7.8 0.022 14.9 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 GAN01916.1 - 8.4e-19 67.7 1.7 2.3e-18 66.3 1.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2854 PF11016.8 GAN01916.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) SurA_N_3 PF13624.6 GAN01919.1 - 0.0063 16.3 0.2 0.0063 16.3 0.2 1.6 2 0 0 2 2 2 1 SurA N-terminal domain Caudo_TAP PF02413.17 GAN01919.1 - 0.0097 16.1 0.7 0.018 15.2 0.7 1.4 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK KdpC PF02669.15 GAN01919.1 - 0.02 14.7 1.6 0.024 14.4 0.1 1.8 1 1 1 2 2 2 0 K+-transporting ATPase, c chain DUF3592 PF12158.8 GAN01919.1 - 0.042 13.9 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Tcp10_C PF07202.13 GAN01919.1 - 0.044 13.8 1.0 0.074 13.0 1.0 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus DUF4834 PF16118.5 GAN01919.1 - 0.14 13.1 4.0 12 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1664 PF07889.12 GAN01920.1 - 0.014 15.4 1.6 0.73 9.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAN01920.1 - 0.064 13.4 1.5 0.1 12.8 1.5 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CKS PF01111.19 GAN01921.1 - 1.1e-30 105.7 3.1 1.1e-30 105.7 3.1 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit DUF334 PF03904.13 GAN01921.1 - 5 6.6 13.4 1.8 8.1 5.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF334) PMT PF02366.18 GAN01923.1 - 1.4e-76 257.3 17.4 1.4e-76 257.3 17.4 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAN01923.1 - 1.6e-58 197.6 15.6 1.6e-58 197.6 15.6 2.0 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAN01923.1 - 8.9e-27 94.1 4.0 6.4e-26 91.4 3.2 2.3 1 1 1 2 2 2 1 MIR domain Mucin_bdg PF03272.13 GAN01923.1 - 0.14 12.2 0.3 0.42 10.6 0.2 1.9 1 1 0 1 1 1 0 Putative mucin or carbohydrate-binding module zf-C2H2_4 PF13894.6 GAN01924.1 - 5.2e-11 42.4 76.9 0.043 14.6 1.0 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN01924.1 - 3.5e-08 33.5 53.9 0.00077 19.7 3.3 7.8 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 GAN01924.1 - 5.5e-05 23.8 28.5 0.15 12.8 2.9 6.9 2 1 5 7 7 7 2 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 GAN01924.1 - 0.00013 20.6 35.9 0.93 7.9 0.2 8.0 8 1 1 9 9 9 6 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 GAN01924.1 - 0.0003 21.1 46.0 0.48 10.8 5.3 6.7 1 1 5 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 GAN01924.1 - 0.0042 17.5 1.2 0.0042 17.5 1.2 9.2 9 0 0 9 9 9 3 Zinc finger, C2H2 type zf-met PF12874.7 GAN01924.1 - 0.012 16.0 72.7 0.079 13.4 0.7 9.2 9 1 0 9 9 9 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 GAN01924.1 - 0.042 13.5 0.6 0.042 13.5 0.6 7.7 9 0 0 9 9 9 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 GAN01924.1 - 1 9.9 42.7 13 6.4 0.1 10.8 9 1 1 10 10 10 0 Zinc-finger double domain DUF2256 PF10013.9 GAN01924.1 - 1.9 8.7 19.2 7.6 6.7 1.1 5.8 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) Aldo_ket_red PF00248.21 GAN01925.1 - 1.6e-54 185.1 0.0 2.1e-53 181.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family MutS_II PF05188.17 GAN01926.1 - 1.1e-11 45.1 0.0 1.7e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 GAN01926.1 - 4.1e-09 36.7 0.0 6.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain I MutS_V PF00488.21 GAN01927.1 - 4.1e-83 278.1 0.6 7.3e-83 277.2 0.6 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAN01927.1 - 1.1e-35 123.6 1.7 1.1e-35 123.6 1.7 2.1 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 GAN01927.1 - 1.1e-12 48.1 1.1 1.1e-12 48.1 1.1 2.2 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 GAN01927.1 - 0.001 18.7 0.0 0.0051 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Aldo_ket_red PF00248.21 GAN01928.1 - 1.5e-56 191.8 0.0 2.2e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_46 PF01374.18 GAN01928.1 - 9e-43 146.3 0.0 1.4e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 DUF5327 PF17261.2 GAN01929.1 - 0.0043 17.8 10.1 0.0043 17.8 10.1 5.1 3 2 0 3 3 1 1 Family of unknown function (DUF5327) MecA PF05389.12 GAN01929.1 - 0.016 14.8 1.9 0.016 14.8 1.9 3.6 2 1 0 2 2 1 0 Negative regulator of genetic competence (MecA) SRP-alpha_N PF04086.13 GAN01929.1 - 0.029 14.3 34.3 0.061 13.2 9.1 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RskA PF10099.9 GAN01929.1 - 0.034 14.5 21.7 0.04 14.2 4.3 3.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Rrp15p PF07890.12 GAN01929.1 - 0.77 10.1 32.8 5.6 7.3 7.6 3.4 3 0 0 3 3 3 0 Rrp15p Eapp_C PF10238.9 GAN01929.1 - 0.86 9.7 35.7 0.22 11.6 7.1 3.4 3 0 0 3 3 3 0 E2F-associated phosphoprotein BRF1 PF07741.13 GAN01929.1 - 1.9 8.9 32.3 0.42 11.0 7.7 3.3 3 0 0 3 3 3 0 Brf1-like TBP-binding domain SURF6 PF04935.12 GAN01929.1 - 2.2 8.0 40.0 4 7.2 13.5 2.4 2 0 0 2 2 2 0 Surfeit locus protein 6 Slu7 PF11708.8 GAN01929.1 - 2.3 7.9 37.4 0.58 9.9 8.5 3.1 3 0 0 3 3 3 0 Pre-mRNA splicing Prp18-interacting factor CDC45 PF02724.14 GAN01929.1 - 2.6 6.3 29.2 0.57 8.4 5.3 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF1764 PF08576.10 GAN01929.1 - 5.3 8.0 33.1 5.2 8.0 8.5 3.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) DUF5523 PF17661.1 GAN01929.1 - 5.6 6.6 33.6 1.5 8.4 7.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5523) Ocular_alb PF02101.15 GAN01929.1 - 6 5.7 11.3 0.4 9.6 0.2 2.5 2 0 0 2 2 2 0 Ocular albinism type 1 protein DUF4820 PF16091.5 GAN01929.1 - 6 6.2 35.2 4.5 6.6 8.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) PNISR PF15996.5 GAN01929.1 - 6.4 7.0 47.2 4.7 7.4 23.6 2.5 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FYDLN_acid PF09538.10 GAN01929.1 - 7.1 7.4 20.7 9.8 6.9 4.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Afi1 PF07792.12 GAN01929.1 - 8.8 6.8 36.0 4.1 7.9 9.0 3.6 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MIT PF04212.18 GAN01930.1 - 5.4e-11 42.4 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 GAN01930.1 - 0.14 12.4 0.1 0.46 10.8 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Rpr2 PF04032.16 GAN01931.1 - 0.0015 18.7 3.6 0.71 10.2 0.2 2.4 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_jaz PF12171.8 GAN01931.1 - 0.0055 17.0 28.0 0.056 13.7 1.4 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN01931.1 - 0.0071 16.7 25.0 0.52 10.8 2.8 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Trm112p PF03966.16 GAN01931.1 - 0.074 13.6 0.2 4.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Trm112p-like protein zinc_ribbon_15 PF17032.5 GAN01931.1 - 0.11 13.3 10.5 8.1 7.3 10.2 2.4 1 1 0 1 1 1 0 zinc-ribbon family DUF629 PF04780.12 GAN01931.1 - 0.16 10.4 16.5 0.086 11.3 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF629) YokU PF14122.6 GAN01931.1 - 0.23 11.5 3.3 4.5 7.3 0.1 2.6 2 1 1 3 3 2 0 YokU-like protein, putative antitoxin CK_II_beta PF01214.18 GAN01931.1 - 0.51 10.1 7.1 1.2 8.9 0.2 2.8 3 0 0 3 3 3 0 Casein kinase II regulatory subunit zf-Dof PF02701.15 GAN01931.1 - 0.52 10.5 0.1 0.52 10.5 0.1 2.6 3 0 0 3 3 3 0 Dof domain, zinc finger zinc-ribbons_6 PF07191.12 GAN01931.1 - 0.74 9.8 9.0 11 6.1 5.9 3.0 2 1 0 2 2 2 0 zinc-ribbons HypA PF01155.19 GAN01931.1 - 1.1 9.3 6.8 2.6 8.1 2.6 2.6 2 2 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 GAN01931.1 - 1.1 10.3 25.2 0.33 11.9 4.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 GAN01932.1 - 1e-17 63.9 74.5 0.0031 17.9 0.6 9.4 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN01932.1 - 4e-06 27.2 93.8 0.19 12.6 1.7 9.9 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN01932.1 - 9e-06 25.8 85.3 0.022 15.0 1.2 9.5 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding Fimbrillin_C PF15495.6 GAN01932.1 - 0.097 13.1 1.1 14 6.2 0.4 3.4 3 1 0 3 3 3 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal zinc_ribbon_15 PF17032.5 GAN01932.1 - 0.3 11.9 39.8 0.54 11.0 0.2 6.1 2 2 2 5 5 5 0 zinc-ribbon family zf-C2H2_2 PF12756.7 GAN01932.1 - 9.9 6.6 57.1 6.8 7.1 0.1 8.5 1 1 7 9 9 9 0 C2H2 type zinc-finger (2 copies) Methyltransf_16 PF10294.9 GAN01933.1 - 1.1e-17 64.4 0.0 2.6e-17 63.1 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Utp11 PF03998.13 GAN01934.1 - 1.1e-75 254.8 31.7 1.2e-75 254.6 31.7 1.0 1 0 0 1 1 1 1 Utp11 protein DUF4164 PF13747.6 GAN01934.1 - 0.014 15.7 3.3 0.014 15.7 3.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) PAS_10 PF13596.6 GAN01934.1 - 0.026 15.1 4.9 0.07 13.7 0.6 3.0 3 1 0 3 3 3 0 PAS domain Lipoprotein_20 PF13942.6 GAN01934.1 - 1.5 8.7 11.8 0.22 11.4 4.0 2.3 2 0 0 2 2 2 0 YfhG lipoprotein DUF3800 PF12686.7 GAN01934.1 - 3.3 8.4 7.3 3.4 8.3 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) WD40 PF00400.32 GAN01935.1 - 3.5e-12 46.6 1.9 2.2e-05 25.1 0.0 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN01935.1 - 6.1e-07 29.7 1.4 0.0034 17.6 0.2 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAN01935.1 - 9.4e-05 22.4 1.4 0.0037 17.3 0.1 2.9 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 GAN01935.1 - 0.00021 21.3 0.4 0.28 11.0 0.0 3.2 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 GAN01935.1 - 0.0041 16.4 0.2 0.0087 15.4 0.2 1.6 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 GAN01935.1 - 0.035 13.4 0.3 0.19 11.0 0.2 1.9 2 0 0 2 2 2 0 WD40-like domain tRNA-synt_1 PF00133.22 GAN01936.1 - 1.7e-228 759.8 1.2 3.9e-228 758.6 0.3 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAN01936.1 - 6.3e-27 94.4 0.1 2.9e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAN01936.1 - 1.9e-14 53.3 0.6 1.1e-06 27.7 0.1 4.4 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAN01936.1 - 0.012 15.0 0.0 0.047 13.0 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PMC2NT PF08066.12 GAN01936.1 - 0.12 13.0 0.2 1.4 9.7 0.0 2.6 2 1 0 2 2 2 0 PMC2NT (NUC016) domain DUF4452 PF14618.6 GAN01937.1 - 0.018 14.9 19.7 0.48 10.3 3.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4452) GHMP_kinases_N PF00288.26 GAN01938.1 - 9.4e-11 41.8 0.1 2.2e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAN01938.1 - 1.7e-05 25.1 0.0 5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4381 PF14316.6 GAN01939.1 - 0.018 15.3 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MAP17 PF15807.5 GAN01939.1 - 0.031 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LMBR1 PF04791.16 GAN01939.1 - 0.063 12.2 0.8 0.095 11.6 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DcuC PF03606.15 GAN01939.1 - 0.1 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Comm PF15957.5 GAN01939.1 - 0.13 12.6 0.2 0.2 12.0 0.2 1.4 1 1 0 1 1 1 0 Commissureless TRP PF06011.12 GAN01939.1 - 0.18 10.5 2.0 0.18 10.5 0.6 1.5 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel PspB PF06667.12 GAN01939.1 - 0.18 11.8 0.4 0.32 11.1 0.4 1.4 1 0 0 1 1 1 0 Phage shock protein B Dickkopf_N PF04706.12 GAN01939.1 - 0.24 11.9 8.9 0.5 10.9 8.9 1.5 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 GAN01939.1 - 0.49 10.7 8.6 2.1 8.7 8.9 1.8 1 1 0 1 1 1 0 EB module XhlA PF10779.9 GAN01939.1 - 1 9.6 2.4 1.8 8.8 2.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA EGF PF00008.27 GAN01939.1 - 2 8.8 9.4 0.18 12.1 1.4 2.3 2 0 0 2 2 2 0 EGF-like domain IBR PF01485.21 GAN01941.1 - 1.3e-08 34.9 17.9 3.2e-07 30.5 11.1 4.8 3 1 2 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 GAN01941.1 - 3.3e-05 23.7 7.4 3.3e-05 23.7 7.4 4.8 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN01941.1 - 0.00038 20.7 9.2 0.00038 20.7 9.2 5.0 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN01941.1 - 0.001 18.9 5.1 0.001 18.9 5.1 5.4 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN01941.1 - 0.0025 17.6 6.6 0.0025 17.6 6.6 4.4 4 2 0 5 5 5 1 Prokaryotic RING finger family 4 FOXP-CC PF16159.5 GAN01942.1 - 0.019 15.5 5.6 0.019 15.5 5.6 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 GAN01942.1 - 1.9 9.1 3.7 0.85 10.2 1.1 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIA PF03153.13 GAN01942.1 - 8.5 6.2 34.2 3 7.8 30.9 1.8 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DPBB_1 PF03330.18 GAN01943.1 - 5e-08 33.1 0.1 1e-07 32.1 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase PRP3 PF08572.10 GAN01945.1 - 0.0075 16.0 11.9 0.077 12.7 5.8 2.5 1 1 1 2 2 2 2 pre-mRNA processing factor 3 (PRP3) TFIIA PF03153.13 GAN01945.1 - 0.26 11.2 21.2 0.33 10.9 21.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Response_reg PF00072.24 GAN01946.1 - 4.4e-21 75.1 0.1 1.8e-14 53.9 0.1 2.9 2 1 0 2 2 2 2 Response regulator receiver domain RasGEF PF00617.19 GAN01947.1 - 2.5e-46 158.1 1.4 2.5e-46 158.1 1.4 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAN01947.1 - 2.4e-10 40.6 5.3 6.5e-10 39.2 1.5 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif zf-met PF12874.7 GAN01948.1 - 2.2e-11 43.8 46.0 0.0084 16.5 0.2 7.9 7 1 1 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN01948.1 - 5.7e-11 42.4 54.7 0.022 15.1 1.8 8.4 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAN01948.1 - 5.7e-06 26.7 65.0 0.28 12.1 0.5 7.9 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAN01948.1 - 0.014 15.7 32.9 0.015 15.6 6.8 5.8 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 GAN01948.1 - 0.017 15.6 65.1 0.53 10.9 0.7 7.7 7 0 0 7 7 7 0 Zinc finger, C2H2 type DUF629 PF04780.12 GAN01948.1 - 0.095 11.2 0.1 0.095 11.2 0.1 6.8 7 1 1 8 8 8 0 Protein of unknown function (DUF629) SARA PF11409.8 GAN01948.1 - 0.33 11.2 0.2 0.33 11.2 0.2 2.9 4 1 1 5 5 3 0 Smad anchor for receptor activation (SARA) GBP_repeat PF02526.14 GAN01948.1 - 0.38 10.5 3.9 11 5.8 0.0 3.6 4 0 0 4 4 4 0 Glycophorin-binding protein FOXP-CC PF16159.5 GAN01948.1 - 0.43 11.2 23.4 17 6.1 2.1 6.5 6 1 1 7 7 7 0 FOXP coiled-coil domain zf_UBZ PF18439.1 GAN01948.1 - 0.55 9.9 0.1 0.55 9.9 0.1 3.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger GFA PF04828.14 GAN01948.1 - 9.3 6.7 19.1 6.1 7.3 0.8 5.0 4 1 1 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme DUF21 PF01595.20 GAN01949.1 - 4.7e-16 59.0 1.4 8.5e-16 58.2 1.4 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAN01949.1 - 3.6e-06 27.3 0.0 0.04 14.4 0.0 3.0 3 0 0 3 3 3 2 CBS domain DUF2967 PF11179.8 GAN01949.1 - 0.069 11.3 4.8 0.089 10.9 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Spt20 PF12090.8 GAN01949.1 - 0.14 11.8 18.3 0.25 10.9 18.3 1.4 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 GAN01949.1 - 0.45 9.3 10.2 0.64 8.8 10.2 1.1 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 GAN01949.1 - 6 5.9 18.8 9.2 5.3 18.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AhpC-TSA PF00578.21 GAN01950.1 - 1.3e-34 118.7 0.0 1.8e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 GAN01950.1 - 1.3e-13 50.5 0.1 2.3e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 GAN01950.1 - 2.1e-13 50.2 0.0 2.9e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 GAN01950.1 - 0.047 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC F-box-like PF12937.7 GAN01951.1 - 2.2e-06 27.5 0.7 4.8e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN01951.1 - 0.0031 17.4 0.1 0.0083 16.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN01952.1 - 3.3e-09 36.5 0.1 7.1e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN01952.1 - 3.3e-06 26.8 0.1 1.5e-05 24.7 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 GAN01952.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 GAN01953.1 - 2.5e-07 30.5 0.0 5.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN01953.1 - 0.026 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain Antimicrobial21 PF14861.6 GAN01953.1 - 0.2 11.4 0.9 0.29 10.9 0.9 1.2 1 0 0 1 1 1 0 Plant antimicrobial peptide zf-C2H2_4 PF13894.6 GAN01954.1 - 4.7e-13 48.8 158.5 0.048 14.5 0.8 15.5 15 0 0 15 15 15 12 C2H2-type zinc finger zf-met PF12874.7 GAN01954.1 - 1.9e-11 44.0 122.9 0.024 15.0 0.1 14.6 14 0 0 14 14 14 11 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN01954.1 - 1.2e-07 31.9 151.2 0.2 12.0 5.4 15.0 15 0 0 15 15 15 12 Zinc-finger double-stranded RNA-binding AvrPphF-ORF-2 PF09143.10 GAN01954.1 - 0.013 15.4 0.3 0.04 13.8 0.1 2.0 2 0 0 2 2 2 0 AvrPphF-ORF-2 zf-C2H2_11 PF16622.5 GAN01954.1 - 0.02 14.6 0.8 0.02 14.6 0.8 9.9 11 0 0 11 11 11 0 zinc-finger C2H2-type Trm112p PF03966.16 GAN01954.1 - 1 10.0 17.6 23 5.7 0.0 6.8 7 0 0 7 7 7 0 Trm112p-like protein START PF01852.19 GAN01955.1 - 1.7e-07 30.8 0.2 0.0036 16.8 0.2 2.7 2 1 0 2 2 2 2 START domain PocR PF10114.9 GAN01955.1 - 0.038 13.8 2.6 0.98 9.2 0.1 3.0 3 0 0 3 3 3 0 Sensory domain found in PocR UCR_14kD PF02271.16 GAN01956.1 - 4e-39 132.6 0.7 4.7e-39 132.4 0.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.11 GAN01956.1 - 0.00034 20.5 0.1 0.00036 20.4 0.1 1.0 1 0 0 1 1 1 1 She9 / Mdm33 family F-box-like PF12937.7 GAN01957.1 - 0.00042 20.1 0.3 0.0015 18.4 0.3 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN01957.1 - 0.0025 18.2 2.7 0.61 10.6 0.1 4.6 3 2 2 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN01957.1 - 0.0031 17.3 2.8 0.011 15.7 0.1 3.1 3 0 0 3 3 3 1 F-box domain Gly_radical PF01228.21 GAN01957.1 - 0.12 12.9 0.1 0.31 11.6 0.1 1.7 1 0 0 1 1 1 0 Glycine radical DIM1 PF02966.16 GAN01958.1 - 4.3e-30 104.2 0.1 4.8e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 RNase_P_p30 PF01876.16 GAN01959.1 - 0.024 14.1 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 RNase P subunit p30 zf-C2H2_4 PF13894.6 GAN01960.1 - 0.00012 22.7 54.0 0.092 13.6 1.4 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 GAN01960.1 - 0.00045 20.5 37.1 0.42 11.1 0.4 7.2 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 GAN01960.1 - 0.02 15.6 23.5 0.082 13.7 3.1 4.4 2 1 3 5 5 5 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 GAN01960.1 - 0.062 13.0 0.1 0.062 13.0 0.1 5.4 6 0 0 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 GAN01960.1 - 0.28 9.7 17.3 1.5 7.2 0.5 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 GAN01960.1 - 0.53 10.6 28.0 2.5 8.5 2.2 5.7 4 2 2 6 6 6 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 GAN01960.1 - 2.2 9.0 13.3 20 5.9 0.5 5.0 6 0 0 6 6 6 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 GAN01960.1 - 2.7 8.6 51.5 1.4 9.5 1.6 7.3 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAN01960.1 - 9.8 6.6 48.3 0.31 11.4 0.4 7.6 7 1 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_jaz PF12171.8 GAN01961.1 - 6.4e-14 51.8 96.7 0.00089 19.5 4.0 11.8 11 0 0 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN01961.1 - 7.8e-13 48.4 102.8 0.0011 19.3 3.8 13.1 13 0 0 13 13 13 9 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN01961.1 - 3.7e-05 24.2 124.0 0.13 13.1 4.8 12.8 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAN01961.1 - 0.0041 17.4 5.5 0.0041 17.4 5.5 10.1 3 2 7 10 10 10 4 C2H2 type zinc-finger (2 copies) NinG PF05766.12 GAN01961.1 - 0.47 10.4 0.1 0.47 10.4 0.1 7.8 9 1 0 9 9 9 0 Bacteriophage Lambda NinG protein Gar1 PF04410.14 GAN01962.1 - 2.2e-41 141.2 5.3 2.2e-41 141.2 5.3 1.9 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region BAR PF03114.18 GAN01963.1 - 5.5e-32 111.3 6.7 7.7e-32 110.8 6.7 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAN01963.1 - 1.5e-16 59.7 0.2 2.8e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN01963.1 - 1e-13 50.9 0.1 1.8e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN01963.1 - 2.4e-10 39.9 0.0 5.4e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3562 PF12085.8 GAN01963.1 - 0.1 12.2 0.1 16 5.2 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3562) KTI12 PF08433.10 GAN01963.1 - 0.16 11.4 2.0 0.23 10.9 2.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Pkinase PF00069.25 GAN01964.1 - 4.4e-50 170.5 0.0 7e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN01964.1 - 2.1e-33 115.7 0.0 2.9e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN01964.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN01964.1 - 2.3e-05 23.4 0.2 0.0002 20.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Ras PF00071.22 GAN01965.1 - 6e-11 42.2 0.0 7.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SARAF PF06682.12 GAN01966.1 - 1.2 8.7 7.3 1.3 8.6 7.3 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SLD5_C PF16922.5 GAN01967.1 - 8.4e-14 51.5 0.1 2.5e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus RSN1_7TM PF02714.15 GAN01968.1 - 7.8e-70 235.3 35.2 1.6e-69 234.3 35.2 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAN01968.1 - 3.5e-34 118.5 0.0 9e-34 117.2 0.0 1.7 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAN01968.1 - 1e-31 109.8 0.2 1e-31 109.8 0.2 3.0 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3343 PF11823.8 GAN01968.1 - 0.0077 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3343) SUIM_assoc PF16619.5 GAN01968.1 - 6.6 6.9 10.3 0.82 9.8 4.8 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Aminotran_4 PF01063.19 GAN01969.1 - 1.4e-22 80.6 0.0 1.8e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV zf-met PF12874.7 GAN01970.1 - 1.4e-11 44.3 23.0 0.026 14.9 1.4 5.3 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN01970.1 - 6e-10 39.2 23.7 0.0023 18.2 2.1 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAN01970.1 - 0.0001 22.6 17.2 0.0075 16.6 2.5 4.0 3 2 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN01970.1 - 0.00045 20.8 37.6 1.8 9.6 0.5 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger Molybdop_Fe4S4 PF04879.16 GAN01970.1 - 0.27 11.3 6.0 0.56 10.2 0.1 3.3 3 0 0 3 3 3 0 Molybdopterin oxidoreductase Fe4S4 domain DUF629 PF04780.12 GAN01970.1 - 0.86 8.1 14.4 0.79 8.2 0.1 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 GAN01970.1 - 5.1 6.8 17.7 0.39 10.4 0.8 3.6 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain MFS_1 PF07690.16 GAN01971.1 - 1.6e-26 93.1 33.6 2.1e-26 92.7 33.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.19 GAN01971.1 - 0.17 12.3 0.8 0.46 10.9 0.8 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Frag1 PF10277.9 GAN01972.1 - 3.8e-36 124.7 11.0 4.4e-36 124.5 11.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family IDO PF01231.18 GAN01973.1 - 1.8e-148 495.0 0.0 3.1e-138 461.2 0.0 2.0 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 GAN01973.1 - 0.036 12.8 0.0 0.071 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) 2-Hacid_dh_C PF02826.19 GAN01974.1 - 1.4e-55 187.5 0.0 1.9e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAN01974.1 - 3.2e-20 72.2 0.0 3.7e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 GAN01974.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DLIC PF05783.11 GAN01975.1 - 7.2e-69 232.8 21.1 2.6e-55 188.1 0.0 5.1 2 1 2 4 4 4 4 Dynein light intermediate chain (DLIC) AAA_29 PF13555.6 GAN01975.1 - 0.014 15.2 0.2 0.036 13.8 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAN01975.1 - 0.022 15.1 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAN01975.1 - 0.03 14.8 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 GAN01975.1 - 0.04 14.5 0.0 0.11 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 GAN01975.1 - 0.055 13.7 0.1 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAN01975.1 - 0.096 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAN01975.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase KilA-N PF04383.13 GAN01976.1 - 0.00083 19.2 1.1 0.003 17.4 0.0 2.4 2 1 0 2 2 2 1 KilA-N domain TFIIA PF03153.13 GAN01976.1 - 2 8.3 21.3 0.13 12.3 12.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 GAN01977.1 - 3e-13 49.4 28.6 4.4e-05 23.7 4.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN01977.1 - 8.7e-12 44.9 27.4 7.9e-07 29.2 1.0 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN01977.1 - 1.1e-08 35.2 24.1 0.0023 18.6 3.4 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN01977.1 - 2.4e-06 27.4 16.9 0.0013 18.7 0.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger Phage_GP20 PF06810.11 GAN01977.1 - 0.0092 15.8 2.7 0.021 14.6 2.7 1.6 1 0 0 1 1 1 1 Phage minor structural protein GP20 bZIP_1 PF00170.21 GAN01977.1 - 0.27 11.4 7.4 0.52 10.5 0.7 2.5 1 1 1 2 2 2 0 bZIP transcription factor Zn-ribbon_8 PF09723.10 GAN01977.1 - 0.33 11.1 10.0 6.5 7.0 0.5 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 GAN01977.1 - 1 9.4 6.7 27 4.8 6.2 2.9 1 1 0 1 1 1 0 zinc-ribbons HALZ PF02183.18 GAN01977.1 - 6.7 7.0 12.0 0.87 9.9 3.4 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper SUR7 PF06687.12 GAN01978.1 - 1.1e-10 41.5 13.1 1.4e-10 41.2 13.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 GAN01978.1 - 0.00011 22.1 6.7 0.00011 22.1 6.7 1.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction CsoSCA PF08936.10 GAN01978.1 - 0.06 12.0 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Cytochrom_C_asm PF01578.20 GAN01978.1 - 0.72 9.6 10.1 1.2 8.9 6.4 2.1 2 0 0 2 2 2 0 Cytochrome C assembly protein DUF4064 PF13273.6 GAN01978.1 - 1.3 9.3 7.0 5 7.4 2.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) zf-NOSIP PF15906.5 GAN01979.1 - 5.9e-15 55.2 1.0 5.9e-15 55.2 1.0 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 GAN01979.1 - 3e-09 36.6 21.2 1.4e-06 28.1 8.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN01979.1 - 8.4e-07 28.9 18.0 0.00026 21.0 6.8 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 GAN01979.1 - 1e-06 29.0 20.3 3.2e-06 27.4 8.4 2.4 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.12 GAN01979.1 - 2.1e-06 27.3 4.9 2.1e-06 27.3 4.9 3.0 1 1 2 3 3 2 1 Rtf2 RING-finger zf-RING_5 PF14634.6 GAN01979.1 - 1.7e-05 24.7 8.9 1.7e-05 24.7 8.9 2.6 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN01979.1 - 0.00036 20.3 4.6 0.00036 20.3 4.6 3.8 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAN01979.1 - 0.0014 18.5 23.9 0.0017 18.2 9.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN01979.1 - 0.0017 18.2 9.5 0.0017 18.2 9.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IL3 PF02059.15 GAN01979.1 - 0.0072 16.4 0.4 0.016 15.2 0.4 1.5 1 0 0 1 1 1 1 Interleukin-3 FYVE PF01363.21 GAN01979.1 - 0.021 14.9 5.6 0.021 14.9 5.6 2.8 2 1 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 GAN01979.1 - 0.035 14.3 19.9 0.045 13.9 7.6 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAN01979.1 - 0.75 9.7 11.5 2.6 8.0 1.7 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 GAN01979.1 - 3.9 7.6 16.2 0.17 11.9 5.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-P11 PF03854.14 GAN01979.1 - 3.9 7.2 23.4 0.034 13.8 6.8 3.2 2 1 1 3 3 3 0 P-11 zinc finger CwfJ_C_2 PF04676.14 GAN01980.1 - 4.4e-34 117.3 1.3 1.8e-33 115.3 0.3 2.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 GAN01980.1 - 1.4e-33 115.3 0.0 2.5e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Asp PF00026.23 GAN01980.1 - 0.33 10.3 1.4 0.55 9.6 1.4 1.3 1 0 0 1 1 1 0 Eukaryotic aspartyl protease HMG_box_5 PF14887.6 GAN01980.1 - 2.5 8.1 6.1 5.8 6.9 1.5 2.9 2 0 0 2 2 2 0 HMG (high mobility group) box 5 PhoLip_ATPase_C PF16212.5 GAN01981.1 - 4.6e-51 174.0 21.0 4.6e-51 174.0 21.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 GAN01981.1 - 4.2e-13 49.2 0.0 3.8e-12 46.1 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAN01981.1 - 2.3e-12 47.7 2.5 5e-06 26.9 2.8 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN01981.1 - 5.3e-09 36.0 0.0 1e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAN01981.1 - 0.00026 20.8 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 GAN01981.1 - 0.1 12.3 3.5 0.32 10.7 3.3 2.0 1 1 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal NapE PF06796.11 GAN01981.1 - 0.54 9.8 2.8 0.5 9.9 0.1 2.4 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE HECT PF00632.25 GAN01982.1 - 8.6e-87 291.5 0.2 8.6e-87 291.5 0.2 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF868 PF05910.12 GAN01982.1 - 0.038 13.6 0.1 0.086 12.5 0.1 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) IQ PF00612.27 GAN01982.1 - 2.9 7.9 6.6 1.5 8.8 3.6 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif Snf7 PF03357.21 GAN01983.1 - 2.1e-45 154.4 24.7 2.1e-45 154.4 24.7 1.5 2 0 0 2 2 2 1 Snf7 Resolvase PF00239.21 GAN01983.1 - 0.035 14.2 8.6 0.21 11.7 7.5 2.2 1 1 1 2 2 2 0 Resolvase, N terminal domain Exonuc_VII_L PF02601.15 GAN01983.1 - 0.22 11.1 5.6 0.27 10.8 5.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 GAN01983.1 - 3.4 7.7 15.2 1.2 9.2 11.3 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YlqD PF11068.8 GAN01983.1 - 4.5 7.6 18.8 21 5.5 11.8 2.3 1 1 1 2 2 2 0 YlqD protein HTH_Tnp_Tc3_2 PF01498.18 GAN01984.1 - 8e-06 26.0 0.6 1.5e-05 25.1 0.6 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 GAN01984.1 - 0.00015 21.6 0.3 0.00099 18.9 0.1 2.3 2 1 1 3 3 3 1 DDE superfamily endonuclease PIF1 PF05970.14 GAN01985.1 - 1.8e-15 57.0 0.1 3.2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase RasGEF PF00617.19 GAN01988.1 - 1.4e-55 188.3 3.5 3.6e-55 186.9 3.5 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN01988.1 - 5.5e-08 33.0 3.9 2.4e-07 30.9 0.2 3.0 2 1 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 GAN01988.1 - 9.7e-05 22.0 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAN01988.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Proteasome PF00227.26 GAN01989.1 - 5.3e-62 208.7 0.2 7.5e-62 208.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAN01989.1 - 7.3e-11 41.6 0.1 2.7e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HEAT PF02985.22 GAN01990.1 - 3.1e-27 92.3 12.4 3.2e-05 23.8 0.3 11.0 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 GAN01990.1 - 1.2e-26 92.9 0.5 4.6e-07 30.1 0.0 7.6 6 1 2 8 8 7 4 HEAT repeats HEAT_EZ PF13513.6 GAN01990.1 - 2.5e-19 69.4 9.6 1.7e-06 28.4 0.1 9.9 8 2 3 11 11 11 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAN01990.1 - 3.1e-14 53.3 0.3 0.0017 18.9 0.0 6.3 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN01990.1 - 1e-12 48.4 7.7 1.1e-06 28.8 0.1 6.0 3 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 GAN01990.1 - 2.3e-11 43.4 2.5 4.1e-11 42.6 0.3 2.8 4 0 0 4 4 2 1 Importin-beta N-terminal domain IFRD PF05004.13 GAN01990.1 - 1.8e-09 37.2 0.1 0.0089 15.2 0.1 5.1 3 1 2 5 5 5 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 GAN01990.1 - 2e-08 34.1 0.3 0.012 15.1 0.0 5.3 4 2 2 6 6 6 3 CLASP N terminal DRIM PF07539.12 GAN01990.1 - 7e-08 31.2 0.0 0.16 10.2 0.0 4.1 3 2 0 3 3 3 3 Down-regulated in metastasis Adaptin_N PF01602.20 GAN01990.1 - 2.6e-07 29.6 3.6 0.0002 20.1 0.1 4.3 3 2 0 3 3 3 1 Adaptin N terminal region MMS19_C PF12460.8 GAN01990.1 - 1.3e-06 27.9 2.9 0.00046 19.4 0.4 3.7 2 1 0 2 2 2 2 RNAPII transcription regulator C-terminal Arm PF00514.23 GAN01990.1 - 2.9e-06 27.1 3.1 4.7 7.4 0.0 6.9 7 1 1 8 8 7 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 GAN01990.1 - 2.5e-05 24.4 0.2 1.4 9.2 0.0 5.0 5 1 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 GAN01990.1 - 8.3e-05 22.5 5.2 7.9 6.4 0.0 7.6 6 2 1 8 8 8 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 GAN01990.1 - 0.00014 21.5 0.5 0.067 12.7 0.0 3.7 4 0 0 4 4 4 1 Tti2 family Importin_rep_6 PF18829.1 GAN01990.1 - 0.0011 19.0 0.5 0.02 15.0 0.2 3.1 3 0 0 3 3 2 1 Importin repeat 6 MMS19_N PF14500.6 GAN01990.1 - 0.0013 18.4 0.1 5.2 6.6 0.0 5.0 3 2 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 GAN01990.1 - 0.0026 17.5 0.0 5.3 6.7 0.0 4.4 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 GAN01990.1 - 0.039 12.5 3.0 0.11 11.0 0.1 3.1 5 0 0 5 5 5 0 CAS/CSE protein, C-terminus DUF2115 PF09888.9 GAN01990.1 - 0.056 14.0 0.1 1.2 9.6 0.0 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) NUC173 PF08161.12 GAN01990.1 - 0.08 12.6 0.0 11 5.6 0.0 4.4 4 1 0 4 4 4 0 NUC173 domain MFS_1 PF07690.16 GAN01991.1 - 2.6e-35 122.0 25.7 3.1e-35 121.7 25.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily eRF1_2 PF03464.15 GAN01992.1 - 3.6e-43 147.1 0.0 7.5e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAN01992.1 - 3.8e-38 130.4 0.1 8.6e-37 126.1 0.0 2.5 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 GAN01992.1 - 2.5e-22 79.2 0.1 1.9e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 eRF1 domain 1 TPR_2 PF07719.17 GAN01992.1 - 2.2e-11 42.9 2.0 0.006 16.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN01992.1 - 3.7e-11 42.3 1.5 0.0031 17.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Lactamase_B PF00753.27 GAN01992.1 - 6.4e-09 36.1 4.3 3.7e-08 33.6 4.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_12 PF13424.6 GAN01992.1 - 1e-08 35.3 2.1 2e-05 24.8 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat baeRF_family10 PF18854.1 GAN01992.1 - 2.2e-08 34.4 0.0 5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 GAN01992.1 - 4.1e-07 30.3 0.0 7.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor TPR_8 PF13181.6 GAN01992.1 - 1.6e-05 24.8 0.9 0.77 10.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN01992.1 - 9.5e-05 22.0 0.3 0.025 14.2 0.1 3.2 4 0 0 4 4 2 1 TPR repeat DUF3856 PF12968.7 GAN01992.1 - 0.00013 22.0 0.6 0.0017 18.4 0.6 2.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 GAN01992.1 - 0.0015 19.0 0.3 1.3 9.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 GAN01992.1 - 0.0049 16.4 0.2 0.0086 15.6 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TOM20_plant PF06552.12 GAN01992.1 - 0.042 13.6 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_21 PF09976.9 GAN01992.1 - 0.048 13.4 0.7 0.084 12.6 0.7 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 GAN01992.1 - 0.065 13.9 3.1 0.71 10.6 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN01992.1 - 0.069 13.4 2.0 0.54 10.5 1.8 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GAN01992.1 - 0.087 12.2 0.1 0.26 10.6 0.1 1.6 1 1 1 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 GAN01992.1 - 0.098 12.7 1.6 14 5.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAN01992.1 - 0.13 12.9 0.7 9.9 6.9 0.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAN01992.1 - 0.18 11.3 0.5 2 8.0 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 GAN01992.1 - 2.3 8.2 3.8 3.4 7.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec5 PF15469.6 GAN01992.1 - 3.9 7.2 5.1 3.4 7.4 0.1 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 Catalase-rel PF06628.12 GAN01993.1 - 0.016 15.4 0.2 11 6.3 0.0 3.5 3 0 0 3 3 3 0 Catalase-related immune-responsive TERB2 PF15101.6 GAN01993.1 - 0.053 13.6 0.2 0.12 12.4 0.2 1.7 1 1 0 1 1 1 0 Telomere-associated protein TERB2 CRR7 PF12095.8 GAN01993.1 - 0.09 13.2 0.2 0.58 10.6 0.0 2.5 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 CTP_synth_N PF06418.14 GAN01994.1 - 1e-124 415.1 0.1 1.4e-124 414.7 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GAN01994.1 - 6.5e-58 195.6 0.0 1.1e-57 194.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAN01994.1 - 4.7e-06 26.5 0.1 2.5e-05 24.2 0.0 2.2 2 1 0 2 2 2 1 Peptidase C26 Complex1_LYR PF05347.15 GAN01995.1 - 8.5e-08 32.1 0.0 9.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAN01995.1 - 0.0005 20.8 0.0 0.00059 20.5 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like PH_9 PF15410.6 GAN01996.1 - 3.8e-34 117.6 2.4 4.6e-34 117.3 0.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 GAN01996.1 - 4.7e-32 111.1 0.1 1e-31 110.0 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 GAN01996.1 - 8.3e-05 23.1 0.1 0.02 15.4 0.0 3.1 3 0 0 3 3 3 1 PH domain HMG_box PF00505.19 GAN01997.1 - 1.8e-17 63.5 2.1 4e-17 62.4 2.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN01997.1 - 1e-07 32.4 0.9 3e-07 30.9 0.9 1.8 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.14 GAN01997.1 - 0.0028 17.7 0.2 0.0073 16.3 0.2 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV MATalpha_HMGbox PF04769.12 GAN01997.1 - 0.18 11.1 0.3 0.29 10.4 0.3 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box HEM4 PF02602.15 GAN01998.1 - 2.4e-36 125.2 0.0 2.8e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Polysacc_deac_1 PF01522.21 GAN01999.1 - 3.7e-23 81.7 0.9 6.2e-23 81.0 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN01999.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 p450 PF00067.22 GAN02000.1 - 4.7e-46 157.5 0.1 5.9e-46 157.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_4 PF12763.7 GAN02001.1 - 2.9e-37 126.8 0.5 1.4e-11 44.2 0.0 3.9 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GAN02001.1 - 7.9e-20 68.9 2.7 0.0023 17.4 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 GAN02001.1 - 1.4e-14 52.7 1.8 0.098 12.6 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 GAN02001.1 - 2.2e-14 53.6 6.5 4e-07 30.4 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 GAN02001.1 - 7.4e-11 41.7 1.9 1.4 8.8 0.0 6.1 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 GAN02001.1 - 2.1e-06 26.9 2.5 0.18 11.4 0.0 4.6 4 0 0 4 4 4 1 EF hand ATG16 PF08614.11 GAN02001.1 - 6.7e-06 26.5 31.9 6.7e-06 26.5 31.9 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 GAN02001.1 - 0.02 14.6 19.9 0.044 13.5 19.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.19 GAN02001.1 - 0.25 9.2 9.1 0.4 8.5 9.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 GAN02001.1 - 0.39 9.3 16.5 0.74 8.4 16.5 1.4 1 0 0 1 1 1 0 AAA domain LPP PF04728.13 GAN02001.1 - 0.5 10.8 7.4 83 3.7 7.4 3.0 1 1 0 1 1 1 0 Lipoprotein leucine-zipper PIN_12 PF16289.5 GAN02001.1 - 0.87 10.1 6.7 2.3 8.7 6.7 1.7 1 0 0 1 1 1 0 PIN domain DUF2333 PF10095.9 GAN02001.1 - 2.9 6.8 12.0 5 6.0 12.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) DUF812 PF05667.11 GAN02001.1 - 3.6 6.4 29.6 0.086 11.7 22.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) PV-1 PF06637.11 GAN02001.1 - 5 5.8 16.2 8.6 5.1 16.2 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) GAS PF13851.6 GAN02001.1 - 5.8 6.2 31.2 0.021 14.2 21.5 1.9 2 0 0 2 2 1 0 Growth-arrest specific micro-tubule binding HSP70 PF00012.20 GAN02001.1 - 6 4.9 12.8 9.2 4.3 12.8 1.1 1 0 0 1 1 1 0 Hsp70 protein FapA PF03961.13 GAN02001.1 - 6.7 5.2 16.6 12 4.4 16.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A VIT1 PF01988.19 GAN02001.1 - 9.6 6.0 6.8 21 4.9 6.8 1.6 1 0 0 1 1 1 0 VIT family E1_DerP2_DerF2 PF02221.15 GAN02002.1 - 1.3e-23 83.9 0.4 1.6e-23 83.6 0.4 1.1 1 0 0 1 1 1 1 ML domain HLH PF00010.26 GAN02004.1 - 6e-16 58.1 3.9 6e-16 58.1 3.9 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.12 GAN02004.1 - 0.0022 16.3 0.8 0.0022 16.3 0.8 1.1 1 0 0 1 1 1 1 Nop14-like family SF-assemblin PF06705.11 GAN02004.1 - 0.023 14.0 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DAHP_synth_1 PF00793.20 GAN02005.1 - 8.4e-101 336.4 0.0 9.9e-101 336.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PHP PF02811.19 GAN02006.1 - 1.6e-16 61.0 0.6 3.1e-16 60.1 0.6 1.5 1 0 0 1 1 1 1 PHP domain Glucosamine_iso PF01182.20 GAN02007.1 - 3.6e-20 72.8 0.0 5.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Asn_synthase PF00733.21 GAN02008.1 - 1.1e-67 229.2 0.0 1.5e-67 228.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 GAN02008.1 - 4.9e-41 139.5 0.0 8.7e-41 138.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAN02008.1 - 2.4e-34 118.4 0.0 1.2e-33 116.1 0.0 2.1 3 0 0 3 3 3 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAN02008.1 - 0.016 14.7 0.0 0.054 12.9 0.0 1.8 2 0 0 2 2 2 0 Aluminium induced protein adh_short PF00106.25 GAN02009.1 - 4.7e-46 156.7 1.4 6.1e-46 156.3 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN02009.1 - 2.1e-35 122.4 0.1 3e-35 121.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN02009.1 - 3.9e-06 26.9 0.7 6.5e-06 26.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN02009.1 - 0.013 15.0 0.3 0.024 14.1 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-C3HC4_3 PF13920.6 GAN02010.1 - 2e-07 30.7 9.4 3.9e-07 29.8 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN02010.1 - 1.9e-06 27.6 11.4 3.6e-06 26.7 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN02010.1 - 2.1e-06 27.6 12.7 4e-06 26.7 12.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAN02010.1 - 3.1e-06 27.0 12.0 7.6e-06 25.7 12.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAN02010.1 - 3.3e-05 23.7 2.2 7.3e-05 22.6 2.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 GAN02010.1 - 3.9e-05 23.6 7.7 9.3e-05 22.4 7.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger BRE1 PF08647.11 GAN02010.1 - 0.00011 22.1 18.2 0.00011 22.1 18.2 6.8 7 1 1 8 8 8 2 BRE1 E3 ubiquitin ligase zf-RING_2 PF13639.6 GAN02010.1 - 0.00014 22.1 11.7 0.00027 21.2 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAN02010.1 - 0.00014 21.6 7.5 0.00029 20.7 7.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAN02010.1 - 0.0047 17.2 8.0 0.015 15.5 8.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 GAN02010.1 - 0.07 13.3 6.4 0.16 12.2 6.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 GAN02010.1 - 0.45 10.3 9.2 2.4 8.0 9.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 GAN02010.1 - 2.1 8.3 5.6 5.4 7.0 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 GAN02010.1 - 2.2 8.4 6.5 5.2 7.2 6.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon Tyr_Deacylase PF02580.16 GAN02011.1 - 2.4e-47 161.1 0.1 2.7e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DEAD PF00270.29 GAN02012.1 - 5.5e-46 156.5 0.0 1.4e-45 155.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN02012.1 - 1.3e-29 102.8 0.0 4.6e-29 101.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN02012.1 - 0.0039 17.2 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAN02012.1 - 0.023 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PPR_2 PF13041.6 GAN02013.1 - 7.7e-19 67.6 16.1 7.5e-06 26.1 0.0 9.6 10 1 0 10 10 10 3 PPR repeat family PPR_3 PF13812.6 GAN02013.1 - 2.6e-14 53.0 1.6 0.00019 21.5 0.1 6.0 5 1 1 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 GAN02013.1 - 7.5e-10 38.4 7.8 0.0093 16.2 0.0 9.4 12 0 0 12 12 12 1 PPR repeat PPR_1 PF12854.7 GAN02013.1 - 2.5e-09 36.6 1.2 6e-06 25.9 0.0 4.8 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 GAN02013.1 - 8.7e-05 22.0 4.3 0.14 11.5 0.0 4.8 4 1 1 5 5 5 1 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 GAN02013.1 - 0.00072 20.0 0.0 3.2 8.2 0.1 3.4 4 0 0 4 4 4 2 Bacterial transcriptional activator domain TPR_19 PF14559.6 GAN02013.1 - 0.0011 19.5 0.0 1.4 9.5 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat NHase_alpha PF02979.16 GAN02013.1 - 0.0069 15.7 0.0 0.024 13.9 0.0 1.9 1 0 0 1 1 1 1 Nitrile hydratase, alpha chain Clathrin PF00637.20 GAN02013.1 - 0.01 15.7 2.3 4.2 7.2 0.2 3.7 3 1 1 4 4 4 0 Region in Clathrin and VPS ANAPC3 PF12895.7 GAN02013.1 - 0.32 11.2 2.1 2.8 8.2 0.1 3.7 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Eaf7 PF07904.13 GAN02014.1 - 1.3e-22 80.1 0.1 3e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 DUF572 PF04502.13 GAN02014.1 - 0.017 14.7 14.5 0.021 14.4 14.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM220 PF15487.6 GAN02014.1 - 1.8 8.2 10.7 2.5 7.6 10.7 1.3 1 0 0 1 1 1 0 FAM220 family FA_desaturase PF00487.24 GAN02015.1 - 3.7e-17 63.0 14.2 8.7e-14 52.0 8.5 2.2 2 0 0 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.8 GAN02015.1 - 3e-07 30.7 0.0 7.7e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3474) CAP_GLY PF01302.25 GAN02016.1 - 5e-19 68.1 0.3 8.6e-19 67.3 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 GAN02016.1 - 2.1e-12 47.0 29.2 6.4e-06 26.4 3.1 5.9 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAN02016.1 - 6.3e-08 32.3 20.5 0.00053 19.7 4.4 4.0 3 0 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 GAN02016.1 - 2.1e-07 30.6 16.9 4.5e-06 26.3 4.2 4.1 1 1 2 3 3 3 2 Leucine-rich repeat Ubiquitin_2 PF14560.6 GAN02016.1 - 2.5e-05 24.7 0.3 0.00013 22.4 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 GAN02016.1 - 0.028 14.2 0.4 0.16 11.7 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin family LRR_6 PF13516.6 GAN02016.1 - 2 8.7 13.7 12 6.3 0.2 5.6 6 0 0 6 6 6 0 Leucine Rich repeat RPN5_C PF18098.1 GAN02016.1 - 9.8 6.4 7.4 5 7.3 2.3 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Glyco_trans_1_3 PF13528.6 GAN02017.1 - 0.00033 20.0 0.0 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 1 tRNA-synt_2b PF00587.25 GAN02018.1 - 4.3e-26 92.0 0.0 8.2e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAN02018.1 - 5.3e-12 45.9 7.2 1e-11 45.0 7.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.6 GAN02018.1 - 0.11 12.6 3.6 0.21 11.8 3.6 1.5 1 0 0 1 1 1 0 Up-regulated During Septation DUF5320 PF17253.2 GAN02018.1 - 0.73 10.9 3.8 6.7 7.9 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DDE_3 PF13358.6 GAN02019.1 - 1.3e-19 70.4 0.0 4.1e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3584 PF12128.8 GAN02019.1 - 0.012 13.1 1.2 0.017 12.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Hydrolase_6 PF13344.6 GAN02020.1 - 1.8e-24 85.8 0.0 1.1e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN02020.1 - 4.5e-21 74.7 0.0 1e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAN02020.1 - 0.00012 22.5 0.0 0.34 11.2 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN02020.1 - 0.12 12.4 0.0 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase p450 PF00067.22 GAN02021.1 - 3.2e-82 276.7 0.4 4e-82 276.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5642 PF18702.1 GAN02022.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) DUF3530 PF12048.8 GAN02023.1 - 0.36 10.2 3.4 0.35 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Kinesin PF00225.23 GAN02025.1 - 2.7e-104 348.7 5.4 2.7e-104 348.7 5.4 4.0 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAN02025.1 - 1.4e-18 67.2 1.0 4.4e-16 59.1 0.0 5.2 4 2 1 5 5 5 2 Microtubule binding Toxin-JAB1 PF15659.6 GAN02025.1 - 1.5 9.2 5.3 0.59 10.5 0.9 2.8 2 1 0 2 2 2 0 JAB-like toxin 1 MFS_1 PF07690.16 GAN02026.1 - 7.9e-26 90.8 41.2 1.2e-25 90.2 36.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4834 PF16118.5 GAN02026.1 - 0.1 13.6 0.1 3.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) HemY_N PF07219.13 GAN02026.1 - 0.27 11.4 1.5 47 4.2 0.0 3.7 3 1 0 3 3 3 0 HemY protein N-terminus OATP PF03137.20 GAN02026.1 - 1.7 6.8 21.5 0.26 9.5 2.0 3.6 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family OTU PF02338.19 GAN02028.1 - 2.5e-13 50.6 0.9 2.3e-12 47.5 1.5 2.2 1 1 1 2 2 2 1 OTU-like cysteine protease CUE PF02845.16 GAN02028.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain DNAPolymera_Pol PF11590.8 GAN02028.1 - 0.027 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Peptidase_C65 PF10275.9 GAN02028.1 - 0.037 13.5 7.8 1.4 8.3 2.3 3.0 3 1 0 3 3 3 0 Peptidase C65 Otubain Silic_transp PF03842.13 GAN02028.1 - 3 6.0 4.5 4.9 5.3 4.5 1.2 1 0 0 1 1 1 0 Silicon transporter KH_1 PF00013.29 GAN02030.1 - 6.4e-72 237.3 19.7 1.3e-12 47.3 0.0 8.8 9 0 0 9 9 9 8 KH domain SLS PF14611.6 GAN02030.1 - 2.3e-06 27.6 6.6 0.23 11.3 0.0 5.0 2 2 2 5 5 5 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 GAN02030.1 - 4.4e-06 26.4 10.9 0.1 12.4 0.0 5.7 6 0 0 6 6 6 3 KH domain PhoPQ_related PF10142.9 GAN02030.1 - 0.027 13.2 2.8 0.77 8.4 0.1 2.8 3 0 0 3 3 3 0 PhoPQ-activated pathogenicity-related protein DUF4974 PF16344.5 GAN02030.1 - 0.058 13.4 0.7 17 5.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) YbbR PF07949.12 GAN02030.1 - 0.25 11.7 12.6 6.8 7.1 0.2 4.9 5 0 0 5 5 5 0 YbbR-like protein DIE2_ALG10 PF04922.12 GAN02031.1 - 8.4e-113 377.6 33.0 1.3e-82 278.3 10.4 2.1 1 1 1 2 2 2 2 DIE2/ALG10 family SKIP_SNW PF02731.15 GAN02032.1 - 5.7e-73 243.9 1.3 5.7e-73 243.9 1.3 2.4 2 0 0 2 2 2 1 SKIP/SNW domain FAM199X PF15814.5 GAN02032.1 - 0.11 11.6 9.8 0.17 10.9 9.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X adh_short PF00106.25 GAN02033.1 - 2.5e-80 268.6 14.0 1.6e-40 138.6 2.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAN02033.1 - 8.9e-65 218.5 11.8 1.1e-32 113.5 0.9 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 GAN02033.1 - 1.1e-33 115.4 0.0 2.7e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 GAN02033.1 - 5.7e-31 107.8 10.1 2.1e-17 63.6 2.0 2.2 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 GAN02033.1 - 5.1e-05 22.7 2.9 0.078 12.3 0.4 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 GAN02033.1 - 0.0007 19.7 0.0 0.0062 16.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.18 GAN02033.1 - 1.6 8.6 7.7 7.8 6.3 0.7 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 GAN02033.1 - 1.8 8.4 6.5 14 5.5 0.4 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase HAD_2 PF13419.6 GAN02034.1 - 2.5e-19 70.1 0.0 3.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN02034.1 - 9.3e-15 55.5 0.9 3.7e-12 47.0 0.3 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN02034.1 - 1.6e-07 31.3 0.1 2.7e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAN02034.1 - 0.019 15.4 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 GAN02035.1 - 2.6e-12 46.5 28.1 7.6e-07 29.2 3.2 4.0 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN02035.1 - 1.6e-10 40.9 14.3 1.3e-06 28.5 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN02035.1 - 9.4e-08 32.3 24.9 0.0021 18.8 1.9 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN02035.1 - 1.2e-07 31.6 6.5 0.012 15.6 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HE PF16278.5 GAN02035.1 - 0.0051 17.2 3.8 0.17 12.3 0.7 2.6 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 GAN02035.1 - 0.026 14.7 1.1 0.026 14.7 1.1 2.2 3 0 0 3 3 2 0 IBR domain, a half RING-finger domain Senescence_reg PF04520.13 GAN02035.1 - 0.028 15.2 2.4 0.073 13.9 0.1 2.3 2 0 0 2 2 2 0 Senescence regulator zf-C2H2_jaz PF12171.8 GAN02035.1 - 0.037 14.3 12.1 0.89 9.9 0.1 4.0 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 GAN02035.1 - 0.077 13.3 6.4 0.089 13.1 1.8 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon DZR PF12773.7 GAN02035.1 - 0.083 12.9 3.5 0.23 11.5 3.5 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-met PF12874.7 GAN02035.1 - 0.15 12.5 5.2 15 6.2 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 GAN02035.1 - 0.33 11.1 2.3 25 5.1 0.0 3.2 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 GAN02035.1 - 0.42 10.4 11.5 2.3 8.1 0.4 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-LYAR PF08790.11 GAN02035.1 - 0.46 10.4 1.9 33 4.5 0.0 3.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 GAN02035.1 - 0.57 10.3 6.7 7.1 6.7 0.6 2.8 2 0 0 2 2 2 0 BED zinc finger LIM PF00412.22 GAN02035.1 - 0.59 10.4 5.2 1.8 8.9 5.2 1.9 1 0 0 1 1 1 0 LIM domain Zn_Tnp_IS1595 PF12760.7 GAN02035.1 - 1.2 9.2 7.9 1.7 8.7 2.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAN02035.1 - 1.9 8.7 7.5 0.94 9.7 2.7 2.6 1 1 1 3 3 3 0 Zinc ribbon domain QWRF PF04484.12 GAN02036.1 - 0.00034 20.5 9.5 0.00075 19.3 9.5 1.5 1 0 0 1 1 1 1 QWRF family DnaI_N PF07319.11 GAN02036.1 - 0.31 11.7 9.5 0.057 14.1 3.8 2.4 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus SET PF00856.28 GAN02037.1 - 2e-08 34.8 0.0 3.5e-07 30.8 0.0 2.0 1 1 1 2 2 2 1 SET domain SAF PF08666.12 GAN02037.1 - 0.084 13.5 0.0 3.1 8.5 0.0 2.3 2 0 0 2 2 2 0 SAF domain SH3_1 PF00018.28 GAN02038.1 - 2.5e-15 55.8 0.1 4e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN02038.1 - 1.2e-14 53.8 0.0 2.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN02038.1 - 5e-12 45.3 0.0 8.2e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Isochorismatase PF00857.20 GAN02040.1 - 7.4e-21 75.1 0.0 1.6e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Mon2_C PF16206.5 GAN02041.1 - 8.1e-90 302.1 3.0 7e-58 196.5 0.9 2.6 1 1 1 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 GAN02041.1 - 4.4e-56 189.4 3.8 4.4e-56 189.4 3.8 2.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 GAN02041.1 - 1e-50 171.7 2.4 1e-50 171.7 2.4 4.0 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAN02041.1 - 0.00011 22.0 0.1 0.028 14.2 0.0 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) bZIP_2 PF07716.15 GAN02042.1 - 9.3e-05 22.4 13.6 9.3e-05 22.4 13.6 2.9 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 GAN02042.1 - 0.00044 20.3 11.6 0.0012 18.9 11.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 GAN02042.1 - 0.014 15.5 27.7 0.016 15.2 27.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc42p PF11544.8 GAN02042.1 - 0.014 15.3 0.0 0.014 15.3 0.0 3.3 3 0 0 3 3 3 0 Spindle pole body component Spc42p DivIC PF04977.15 GAN02042.1 - 0.03 14.1 1.6 0.03 14.1 1.6 3.0 2 1 1 3 3 3 0 Septum formation initiator bZIP_Maf PF03131.17 GAN02042.1 - 4 8.0 30.5 0.049 14.2 12.2 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Exonuc_VII_L PF02601.15 GAN02042.1 - 5.9 6.4 16.0 8.9 5.8 16.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Coiled-coil_56 PF09813.9 GAN02044.1 - 0.00094 19.2 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF423 PF04241.15 GAN02044.1 - 0.015 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Nup54 PF13874.6 GAN02045.1 - 3.8e-36 124.3 8.6 3.8e-36 124.3 8.6 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 GAN02045.1 - 0.00074 20.3 93.5 0.18 12.6 26.6 4.1 1 1 1 3 3 3 2 Nucleoporin FG repeat region NPV_P10 PF05531.12 GAN02045.1 - 0.0087 16.5 1.7 3.1 8.3 0.1 3.1 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Nup54_C PF18437.1 GAN02045.1 - 0.074 13.0 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain DUF1128 PF06569.11 GAN02045.1 - 0.17 11.9 3.2 8.2 6.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1128) Translin PF01997.16 GAN02045.1 - 0.3 11.0 5.6 0.045 13.7 1.6 1.6 2 0 0 2 2 2 0 Translin family CorA PF01544.18 GAN02045.1 - 2.2 7.5 6.2 0.48 9.7 2.6 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 GAN02045.1 - 9.8 6.2 7.7 3.1 7.9 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SICA_alpha PF12887.7 GAN02046.1 - 0.021 14.7 0.1 0.026 14.4 0.1 1.1 1 0 0 1 1 1 0 SICA extracellular alpha domain Vps8 PF12816.7 GAN02047.1 - 0.01 15.4 1.4 0.022 14.3 0.7 1.8 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 Noelin-1 PF12308.8 GAN02047.1 - 0.16 11.9 4.6 0.42 10.6 4.6 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein Sec1 PF00995.23 GAN02048.1 - 1.9e-125 420.4 0.0 1.9e-125 420.4 0.0 1.3 2 0 0 2 2 2 1 Sec1 family 60KD_IMP PF02096.20 GAN02048.1 - 0.02 14.8 1.2 0.039 13.9 1.2 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein Glycos_transf_2 PF00535.26 GAN02048.1 - 0.049 13.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 YlbD_coat PF14071.6 GAN02048.1 - 7.6 6.8 7.3 5.9 7.2 0.4 3.2 3 0 0 3 3 3 0 Putative coat protein PRIMA1 PF16101.5 GAN02048.1 - 7.9 6.5 8.3 0.44 10.6 0.9 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MBOAT PF03062.19 GAN02049.1 - 1.6e-45 156.0 7.5 2.5e-45 155.4 7.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FMO-like PF00743.19 GAN02050.1 - 1.4e-22 79.9 0.1 1.1e-21 76.9 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAN02050.1 - 2.8e-13 49.7 1.9 3.6e-09 36.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAN02050.1 - 8.5e-11 41.6 0.0 1e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN02050.1 - 5.1e-09 35.8 0.1 4.1e-06 26.3 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN02050.1 - 6.4e-09 35.9 0.0 2.6e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAN02050.1 - 8.3e-07 29.1 3.5 0.025 14.6 0.2 4.0 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 GAN02050.1 - 1.6e-05 24.6 0.0 0.028 14.0 0.0 2.2 2 1 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 GAN02050.1 - 0.00059 19.9 0.0 0.48 10.5 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 GAN02050.1 - 0.0039 16.3 0.1 0.022 13.8 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A PQQ_2 PF13360.6 GAN02051.1 - 1.3e-13 51.1 0.3 3.3e-11 43.2 0.3 2.9 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 GAN02051.1 - 6.7e-13 47.9 6.9 0.00094 19.0 0.1 4.4 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.6 GAN02051.1 - 5.4e-08 33.1 3.9 0.043 14.3 0.1 5.1 5 0 0 5 5 5 3 PQQ-like domain SH3_1 PF00018.28 GAN02052.1 - 1.2e-11 44.0 0.0 2.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN02052.1 - 1.6e-08 34.1 0.1 8.3e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 GAN02052.1 - 1.2e-07 31.5 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 GAN02052.1 - 0.031 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_4 PF06347.13 GAN02052.1 - 0.077 12.8 0.2 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial SH3 domain Mito_carr PF00153.27 GAN02053.1 - 5.6e-73 241.0 0.8 4.8e-25 87.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN02053.1 - 6.7e-05 22.2 1.4 3 6.9 0.0 4.5 3 1 1 5 5 5 2 Gammaproteobacterial serine protease EF-hand_6 PF13405.6 GAN02053.1 - 0.00058 19.6 0.0 0.0025 17.6 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 GAN02053.1 - 0.0022 17.4 0.0 0.0078 15.7 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 GAN02053.1 - 0.0023 18.4 0.1 0.0052 17.2 0.1 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAN02053.1 - 0.05 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 EF hand WD40 PF00400.32 GAN02054.1 - 7.1e-17 61.5 8.7 2.2e-05 25.1 0.0 5.7 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02054.1 - 4.6e-07 30.0 0.1 0.063 13.6 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN02054.1 - 0.072 13.0 0.4 1.7 8.5 0.0 2.9 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A FAD_binding_3 PF01494.19 GAN02055.1 - 3.5e-21 75.9 0.1 2e-20 73.3 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAN02055.1 - 0.0005 19.8 0.0 0.21 11.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 GAN02055.1 - 0.00076 18.6 0.1 0.0027 16.8 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 GAN02055.1 - 0.0015 18.7 0.1 0.0041 17.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAN02055.1 - 0.0017 17.5 0.0 0.005 16.0 0.0 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAN02055.1 - 0.0039 16.5 0.1 0.14 11.3 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAN02055.1 - 0.0052 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAN02055.1 - 0.039 14.5 0.1 0.37 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAN02055.1 - 0.081 11.8 2.9 1.9 7.2 0.1 3.1 4 0 0 4 4 4 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 GAN02055.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Metallophos PF00149.28 GAN02056.1 - 3.1e-16 60.5 1.1 6.2e-16 59.5 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAN02056.1 - 4e-05 23.9 0.0 0.003 17.7 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF2464 PF10240.9 GAN02056.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.8 1 0 0 1 1 1 0 Multivesicular body subunit 12 CNH PF00780.22 GAN02057.1 - 2e-51 175.2 0.0 3e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAN02057.1 - 1.2e-32 113.6 0.6 2.5e-32 112.6 0.6 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 GAN02057.1 - 2.1e-20 73.2 0.1 8.2e-20 71.3 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 GAN02057.1 - 0.0084 16.1 0.0 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_16 PF17838.1 GAN02057.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.8 2 0 0 2 2 2 0 PH domain DNA_repr_REX1B PF14966.6 GAN02058.1 - 2.1e-26 92.4 5.1 1.4e-25 89.8 1.1 2.1 1 1 1 2 2 2 1 DNA repair REX1-B CdvA PF18822.1 GAN02058.1 - 0.00025 20.8 6.6 0.13 12.1 1.3 3.1 1 1 1 2 2 2 2 CdvA-like coiled-coil domain DUF1722 PF08349.11 GAN02058.1 - 0.012 15.9 1.4 2 8.7 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1722) Syntaxin_2 PF14523.6 GAN02058.1 - 0.015 15.6 7.7 0.15 12.5 7.7 2.1 1 1 0 1 1 1 0 Syntaxin-like protein FlgN PF05130.12 GAN02058.1 - 0.025 15.1 5.4 0.14 12.7 0.9 2.2 2 0 0 2 2 2 0 FlgN protein DUF1024 PF06260.12 GAN02058.1 - 0.054 13.8 2.4 0.092 13.0 0.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1024) AAA_15 PF13175.6 GAN02058.1 - 0.071 12.8 7.2 0.081 12.6 7.2 1.0 1 0 0 1 1 1 0 AAA ATPase domain YkyA PF10368.9 GAN02058.1 - 0.24 11.0 16.8 1.1 8.9 0.9 2.4 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein ParB PF08775.10 GAN02058.1 - 0.35 11.4 7.3 0.34 11.4 0.4 2.7 1 1 2 3 3 3 0 ParB family Laminin_II PF06009.12 GAN02058.1 - 0.39 10.7 7.4 0.44 10.5 0.5 2.7 2 1 1 3 3 3 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 GAN02058.1 - 0.48 10.6 13.7 0.84 9.8 13.7 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 GAN02058.1 - 0.51 10.4 15.5 6.3 6.9 15.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cauli_AT PF03233.13 GAN02058.1 - 0.52 10.2 9.2 1.1 9.2 9.1 1.6 1 1 0 1 1 1 0 Aphid transmission protein Occludin_ELL PF07303.13 GAN02058.1 - 0.54 11.0 5.8 0.78 10.5 0.8 2.6 1 1 2 3 3 3 0 Occludin homology domain ZYG-11_interact PF05884.12 GAN02058.1 - 0.6 9.5 3.0 0.86 9.0 2.9 1.4 1 1 0 1 1 1 0 Interactor of ZYG-11 DUF5082 PF16888.5 GAN02058.1 - 0.6 10.4 9.6 2.6 8.3 3.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) COG2 PF06148.11 GAN02058.1 - 0.65 10.1 10.9 0.66 10.1 1.0 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 GAN02058.1 - 0.7 10.4 11.4 1.2 9.7 10.7 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Carbpep_Y_N PF05388.11 GAN02058.1 - 0.83 10.2 5.0 3.7 8.1 2.0 2.2 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Amidase PF01425.21 GAN02058.1 - 0.9 8.4 2.6 3.3 6.6 0.3 1.9 1 1 1 2 2 2 0 Amidase Med4 PF10018.9 GAN02058.1 - 1.8 8.2 12.1 0.68 9.6 4.4 2.7 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 HAUS-augmin3 PF14932.6 GAN02058.1 - 2.1 7.9 11.4 1 8.9 5.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 PMC2NT PF08066.12 GAN02058.1 - 2.7 8.7 6.5 5.7 7.7 2.7 2.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain YojJ PF10372.9 GAN02058.1 - 3.2 7.9 6.5 1.1 9.5 0.1 2.7 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus zf-C4H2 PF10146.9 GAN02058.1 - 3.4 7.9 10.5 0.28 11.5 5.3 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein Nup54 PF13874.6 GAN02058.1 - 3.6 7.7 9.6 4 7.6 1.0 3.0 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 FeoB_Cyto PF17910.1 GAN02058.1 - 4 8.1 8.2 7.1 7.2 4.7 2.4 2 1 0 2 2 2 0 FeoB cytosolic helical domain DUF1664 PF07889.12 GAN02058.1 - 4.2 7.4 11.9 5.1 7.1 1.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ACCA PF03255.14 GAN02058.1 - 4.7 7.1 8.5 11 5.9 2.9 2.7 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fib_alpha PF08702.10 GAN02058.1 - 5.8 7.1 11.7 1.8 8.7 6.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 GAN02058.1 - 7.9 6.8 8.9 7.9 6.8 1.4 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Kinesin PF00225.23 GAN02060.1 - 1.2e-110 369.6 0.3 2.5e-110 368.5 0.3 1.6 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 GAN02060.1 - 6e-45 153.6 2.0 6e-45 153.6 2.0 3.7 3 0 0 3 3 3 1 Kinesin-associated DUF3694 PF12473.8 GAN02060.1 - 2.8e-38 132.0 3.3 3.1e-38 131.9 0.3 2.7 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 GAN02060.1 - 8.3e-28 97.2 2.1 9e-28 97.1 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 GAN02060.1 - 1.6e-14 54.3 0.5 8e-14 52.0 0.2 2.4 2 0 0 2 2 2 1 PH domain KIF1B PF12423.8 GAN02060.1 - 0.00022 21.6 0.1 0.00078 19.8 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 GAN02060.1 - 0.0089 16.4 0.1 0.075 13.4 0.0 2.8 3 0 0 3 3 3 1 FHA domain PH_9 PF15410.6 GAN02060.1 - 0.017 15.5 0.4 0.12 12.8 0.4 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain DUF2151 PF10221.9 GAN02062.1 - 1.2e-07 30.8 8.9 1.2e-05 24.2 0.9 3.7 2 2 1 3 3 3 2 Cell cycle and development regulator SR-25 PF10500.9 GAN02062.1 - 0.71 9.4 5.3 1.2 8.7 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FGE-sulfatase PF03781.16 GAN02063.1 - 9.1e-38 130.3 3.0 1.5e-37 129.6 3.0 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 UCH PF00443.29 GAN02065.1 - 4.4e-48 164.0 0.1 7.2e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN02065.1 - 2.4e-15 56.9 0.0 1.3e-14 54.6 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GAN02065.1 - 4.4e-09 36.5 0.1 2.1e-08 34.3 0.1 2.1 1 1 0 1 1 1 1 MATH domain RTC4 PF14474.6 GAN02066.1 - 4.6e-23 81.7 0.1 1.4e-22 80.1 0.0 1.9 1 1 1 2 2 2 1 RTC4-like domain EF-hand_1 PF00036.32 GAN02066.1 - 0.0042 16.5 1.4 0.009 15.5 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GAN02066.1 - 0.13 11.8 1.6 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 GAN02066.1 - 0.24 11.4 1.5 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain UPF1_Zn_bind PF09416.10 GAN02066.1 - 4 7.4 7.8 1.4 8.9 2.0 2.3 2 1 0 2 2 2 0 RNA helicase (UPF2 interacting domain) Phosphoesterase PF04185.14 GAN02067.1 - 2.2e-30 106.1 6.9 8.4e-29 100.9 6.9 2.1 1 1 0 1 1 1 1 Phosphoesterase family zf-RING_2 PF13639.6 GAN02068.1 - 1.7e-11 44.3 4.8 2.9e-11 43.5 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAN02068.1 - 2.3e-09 37.4 2.7 5.4e-09 36.2 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAN02068.1 - 1.4e-08 34.4 5.5 3.1e-08 33.3 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN02068.1 - 4.5e-07 29.6 4.6 9.2e-07 28.6 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN02068.1 - 2.9e-06 27.2 6.0 5.7e-06 26.3 0.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAN02068.1 - 8.2e-06 25.5 2.7 8.2e-06 25.5 2.7 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GAN02068.1 - 2.5e-05 24.1 2.7 5.5e-05 23.0 2.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN02068.1 - 5.5e-05 22.9 6.8 0.0001 22.1 6.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GAN02068.1 - 0.00012 21.7 5.7 0.00025 20.6 5.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 GAN02068.1 - 0.00021 21.1 6.6 0.00037 20.3 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN02068.1 - 0.00039 20.4 3.4 0.00073 19.5 3.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 GAN02068.1 - 0.0036 17.4 3.5 0.013 15.6 3.5 2.1 1 1 0 1 1 1 1 RING-variant domain zf-Nse PF11789.8 GAN02068.1 - 0.0044 16.8 1.6 0.0076 16.1 1.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 GAN02068.1 - 0.0095 16.0 7.1 0.035 14.2 1.0 3.1 2 1 1 3 3 3 1 KIAA1045 RING finger zf-RING_4 PF14570.6 GAN02068.1 - 0.0098 15.7 3.5 0.017 14.9 3.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain TNFR_16_TM PF18422.1 GAN02068.1 - 0.016 15.1 0.3 0.05 13.6 0.3 1.8 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain zf-C3H2C3 PF17122.5 GAN02068.1 - 0.025 14.6 4.3 0.066 13.3 4.3 1.8 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 GAN02068.1 - 0.038 13.9 5.8 0.066 13.1 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FtsK_SpoIIIE PF01580.18 GAN02068.1 - 0.055 12.8 0.2 0.075 12.4 0.2 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Tmemb_55A PF09788.9 GAN02068.1 - 0.055 12.5 0.9 0.11 11.5 0.9 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A LMBR1 PF04791.16 GAN02068.1 - 0.069 12.1 0.2 0.08 11.8 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF999 PF06198.11 GAN02068.1 - 0.07 13.1 0.1 0.095 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) FANCL_C PF11793.8 GAN02068.1 - 0.097 12.9 9.2 1.5 9.0 7.6 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 GAN02068.1 - 0.13 12.6 4.6 0.32 11.4 4.6 1.8 1 0 0 1 1 1 0 RING-like domain HlyD PF00529.20 GAN02068.1 - 0.21 11.5 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS zf-C3HC4_4 PF15227.6 GAN02068.1 - 0.47 10.7 5.3 1.3 9.3 4.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.29 GAN02068.1 - 0.48 10.4 6.6 1.8 8.5 6.6 2.0 1 1 1 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 GAN02068.1 - 0.5 10.3 6.6 0.14 12.2 2.8 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Rtf2 PF04641.12 GAN02068.1 - 0.54 9.6 6.0 0.89 8.9 6.0 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger C1_1 PF00130.22 GAN02068.1 - 3.5 7.6 8.2 1.5 8.8 0.9 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ofd1_CTDD PF10637.9 GAN02069.1 - 6.3e-73 245.3 0.0 1.1e-69 234.6 0.0 2.4 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 GAN02069.1 - 8.7e-28 96.8 0.0 1.8e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAN02069.1 - 7.2e-13 49.2 0.0 1.5e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 4HBT PF03061.22 GAN02070.1 - 3e-12 46.7 0.1 4.3e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 GAN02070.1 - 0.025 14.7 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 GAN02070.1 - 0.097 12.9 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Thioredoxin PF00085.20 GAN02072.1 - 4.8e-34 116.4 0.1 9.7e-25 86.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 GAN02072.1 - 1.5e-07 31.8 0.3 0.002 18.6 0.1 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAN02072.1 - 2.1e-06 28.0 2.0 0.17 12.2 0.5 4.8 2 2 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 GAN02072.1 - 3.4e-05 23.4 0.0 0.011 15.1 0.0 2.9 2 1 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 GAN02072.1 - 0.003 17.6 0.2 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.6 GAN02072.1 - 0.0049 16.7 1.4 2.4 7.9 0.0 3.5 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 GAN02072.1 - 0.089 13.0 0.1 1.1 9.5 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin-like Caskin-Pro-rich PF16907.5 GAN02072.1 - 0.09 13.3 0.3 0.16 12.5 0.3 1.4 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Ish1 PF10281.9 GAN02072.1 - 0.15 12.4 1.1 2.7 8.4 0.2 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein FMO-like PF00743.19 GAN02073.1 - 2.2e-44 151.8 0.0 9.3e-32 110.1 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAN02073.1 - 5.8e-19 68.5 0.1 9.9e-13 48.0 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAN02073.1 - 3.6e-16 59.3 0.0 1.8e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAN02073.1 - 8.1e-09 35.1 0.2 2.7e-07 30.1 0.0 2.7 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN02073.1 - 2.4e-08 34.1 0.0 7.5e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAN02073.1 - 1e-06 28.6 0.2 0.00092 18.9 0.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAN02073.1 - 1.6e-05 25.0 1.3 0.00021 21.3 0.2 2.9 2 2 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAN02073.1 - 5.3e-05 23.7 0.6 0.038 14.6 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN02073.1 - 8.6e-05 22.0 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAN02073.1 - 0.00012 21.5 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 GAN02073.1 - 0.0018 17.6 0.1 0.0054 16.0 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAN02073.1 - 0.003 16.3 0.0 0.043 12.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAN02073.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAN02073.1 - 0.011 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 GAN02073.1 - 0.012 16.0 0.0 7.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 GAN02073.1 - 0.042 13.4 0.1 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 GAN02073.1 - 0.12 12.5 0.2 8.6 6.4 0.1 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF373 PF04123.13 GAN02074.1 - 0.0018 17.8 1.6 0.0023 17.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Yip1 PF04893.17 GAN02074.1 - 0.068 12.9 3.3 0.27 11.0 2.4 2.0 2 0 0 2 2 2 0 Yip1 domain Pkinase PF00069.25 GAN02075.1 - 2e-75 253.6 0.0 2.8e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02075.1 - 6.4e-40 137.1 0.0 2e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 GAN02075.1 - 7.1e-15 55.1 0.1 2e-14 53.7 0.1 1.8 1 0 0 1 1 1 1 FHA domain Haspin_kinase PF12330.8 GAN02075.1 - 3.5e-05 22.9 0.1 5.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN02075.1 - 0.00011 21.7 0.0 0.00034 20.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAN02075.1 - 0.00037 19.4 0.0 0.00065 18.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAN02075.1 - 0.00047 19.6 0.1 0.00085 18.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN02075.1 - 0.04 13.8 0.0 2.6 7.9 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 GAN02075.1 - 0.18 12.1 0.0 0.59 10.5 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Sugar_tr PF00083.24 GAN02076.1 - 4.9e-110 368.5 17.1 6e-110 368.2 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN02076.1 - 8.2e-27 94.0 31.7 1.9e-16 60.0 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN02076.1 - 8.2e-06 24.5 1.0 8.2e-06 24.5 1.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.19 GAN02076.1 - 0.015 15.2 0.0 0.015 15.2 0.0 3.0 3 1 0 3 3 3 0 VIT family ArAE_1 PF06081.11 GAN02076.1 - 0.67 10.1 10.4 1.3 9.1 1.3 3.3 2 1 1 3 3 3 0 Aromatic acid exporter family member 1 Acyl-CoA_dh_1 PF00441.24 GAN02077.1 - 1.2e-30 106.7 0.1 2.4e-30 105.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 GAN02077.1 - 7e-21 74.2 0.0 1.9e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 GAN02077.1 - 3e-16 59.4 0.1 5.1e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAN02077.1 - 3.8e-12 46.8 0.0 1.7e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAN02077.1 - 0.00081 19.7 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bax1-I PF01027.20 GAN02078.1 - 1.1e-52 179.0 31.5 1.2e-52 178.8 31.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CDC24_OB3 PF17244.2 GAN02079.1 - 5.6e-64 215.9 2.2 8.9e-64 215.3 1.9 1.5 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB2 PF17245.2 GAN02079.1 - 9.9e-25 87.6 0.1 2.2e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 GAN02079.1 - 9.6e-20 70.9 0.0 2.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 REPA_OB_2 PF16900.5 GAN02079.1 - 0.012 15.5 0.1 5.4 7.0 0.1 2.9 2 1 1 3 3 3 0 Replication protein A OB domain GPI-anchored PF10342.9 GAN02080.1 - 7.1e-06 26.7 0.2 7.1e-06 26.7 0.2 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.25 GAN02081.1 - 3.1e-68 230.0 0.0 5.2e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02081.1 - 4.9e-41 140.7 0.0 8e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN02081.1 - 7.4e-09 35.3 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN02081.1 - 0.0012 18.2 0.2 0.0012 18.2 0.2 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN02081.1 - 0.0097 15.8 0.8 0.14 12.0 0.5 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Act-Frag_cataly PF09192.10 GAN02081.1 - 0.076 12.4 1.0 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 Actin-fragmin kinase, catalytic Miga PF10265.9 GAN02081.1 - 0.98 8.3 5.7 0.49 9.3 3.3 1.8 1 1 0 1 1 1 0 Mitoguardin Trp_oprn_chp PF09534.10 GAN02082.1 - 0.017 14.9 0.2 0.44 10.3 0.0 2.1 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 GAN02082.1 - 0.63 11.0 5.5 5.2 8.0 0.0 3.3 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 GAN02082.1 - 7.1 6.5 7.0 7.5 6.5 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pmp3 PF01679.17 GAN02084.1 - 9.5e-22 76.9 11.6 1.1e-21 76.7 11.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TctA PF01970.16 GAN02084.1 - 0.77 8.4 3.2 0.86 8.3 3.2 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DHHC PF01529.20 GAN02085.1 - 7.1e-07 29.4 9.5 0.0041 17.2 0.6 3.1 3 0 0 3 3 3 2 DHHC palmitoyltransferase Ion_trans PF00520.31 GAN02086.1 - 1.3e-138 460.1 88.0 1e-40 139.5 13.6 4.1 4 0 0 4 4 4 4 Ion transport protein EF-hand_7 PF13499.6 GAN02086.1 - 0.0024 18.3 0.1 0.03 14.8 0.4 2.7 3 0 0 3 3 3 1 EF-hand domain pair GPHH PF16905.5 GAN02086.1 - 0.003 17.3 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 GAN02086.1 - 0.036 13.6 0.0 0.55 9.9 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 GAN02086.1 - 0.067 13.2 0.1 0.54 10.3 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain TPT PF03151.16 GAN02087.1 - 1.6e-13 50.7 6.7 2.1e-13 50.3 6.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN02087.1 - 5.7e-06 26.5 14.9 0.0015 18.7 7.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1129 PF06570.11 GAN02087.1 - 0.011 15.3 1.6 0.011 15.3 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) PIG-U PF06728.13 GAN02087.1 - 0.037 13.1 11.0 0.15 11.0 11.0 1.9 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U FtsX PF02687.21 GAN02087.1 - 0.57 10.7 0.0 0.57 10.7 0.0 2.8 3 0 0 3 3 3 0 FtsX-like permease family DUF1700 PF08006.11 GAN02087.1 - 3.8 7.0 9.2 0.36 10.3 4.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) VHS PF00790.19 GAN02088.1 - 7.8e-40 136.0 1.5 5.1e-39 133.3 0.1 2.5 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 GAN02088.1 - 7.9e-17 61.2 12.0 1.6e-16 60.1 12.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 GAN02088.1 - 1.8e-06 27.5 7.7 0.017 15.0 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 GAN02088.1 - 4.9e-05 23.6 3.5 4.9e-05 23.5 0.9 2.4 2 1 0 2 2 2 1 GAT domain Hrs_helical PF12210.8 GAN02088.1 - 6.4e-05 23.4 1.7 6.4e-05 23.4 1.7 2.3 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE_2 PF02318.16 GAN02088.1 - 0.0012 19.0 5.0 0.0012 19.0 5.0 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger HypA PF01155.19 GAN02088.1 - 0.024 14.6 5.3 0.14 12.1 2.6 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 GAN02088.1 - 1.9 8.6 13.0 1.5e+02 2.5 13.0 2.4 1 1 0 1 1 1 0 Double zinc ribbon PIG-X PF08320.12 GAN02089.1 - 1.6e-37 129.5 0.2 1.8e-37 129.3 0.2 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Band_7 PF01145.25 GAN02090.1 - 1.6e-24 86.9 2.2 2.9e-24 86.1 2.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 GAN02090.1 - 0.073 13.2 0.6 0.36 10.9 0.5 2.1 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain Glyco_hydro_16 PF00722.21 GAN02091.1 - 1.6e-26 92.9 0.1 2.2e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Invasin_D3 PF09134.10 GAN02091.1 - 0.044 14.1 0.4 0.19 12.1 0.1 2.1 1 1 1 2 2 2 0 Invasin, domain 3 MFS_1 PF07690.16 GAN02092.1 - 2.6e-53 181.2 32.3 1.2e-52 179.0 21.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN02092.1 - 2.1e-09 36.8 12.1 2.1e-09 36.8 12.1 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter Mucin15 PF15672.5 GAN02092.1 - 0.068 12.7 0.9 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 CNDH2_N PF06278.11 GAN02092.1 - 1.2 9.4 3.4 44 4.3 1.3 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Transgly_assoc PF04226.13 GAN02092.1 - 1.5 9.2 7.1 5.2 7.4 4.5 2.8 2 0 0 2 2 2 0 Transglycosylase associated protein FGGY_N PF00370.21 GAN02093.1 - 3e-72 243.1 0.0 4.2e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAN02093.1 - 4.6e-70 235.4 0.6 6.7e-69 231.6 0.5 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Glyco_hydro_9 PF00759.19 GAN02094.1 - 1.1e-110 370.9 11.1 1.3e-110 370.7 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 YajC PF02699.15 GAN02094.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4381 PF14316.6 GAN02094.1 - 0.03 14.5 0.3 0.086 13.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 GAN02094.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM190 PF15431.6 GAN02094.1 - 0.13 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 DPBB_1 PF03330.18 GAN02095.1 - 1.3e-09 38.2 0.1 1.3e-09 38.2 0.1 2.3 2 2 0 2 2 2 1 Lytic transglycolase DUF572 PF04502.13 GAN02095.1 - 0.02 14.5 27.6 0.025 14.2 27.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.14 GAN02095.1 - 0.09 11.1 14.3 0.12 10.7 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 GAN02095.1 - 0.1 11.2 21.5 0.11 11.0 21.5 1.1 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 GAN02095.1 - 0.17 10.0 33.6 0.19 9.8 33.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 GAN02095.1 - 0.24 8.5 17.7 0.26 8.4 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 GAN02095.1 - 0.35 11.4 15.5 0.47 11.0 15.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.9 GAN02095.1 - 0.75 8.6 19.3 1 8.1 19.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pneumo_att_G PF05539.11 GAN02095.1 - 1.4 8.5 27.4 1.8 8.1 27.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF936 PF06075.12 GAN02095.1 - 1.5 7.7 28.7 1.9 7.3 28.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PAP1 PF08601.10 GAN02095.1 - 2 8.1 25.1 2.7 7.7 25.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Presenilin PF01080.17 GAN02095.1 - 2.1 7.0 19.2 2.6 6.7 19.2 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GAN02095.1 - 2.4 7.9 24.9 3.8 7.3 24.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.6 GAN02095.1 - 5.9 5.6 18.6 7.2 5.3 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SWI-SNF_Ssr4 PF08549.10 GAN02095.1 - 7.4 5.1 15.6 9.6 4.7 15.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MIF PF01187.18 GAN02096.1 - 3e-15 56.5 0.0 3.1e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 GAN02096.1 - 0.0013 18.6 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Tautomerase enzyme CAP_N PF01213.19 GAN02097.1 - 0.21 11.0 5.7 0.048 13.2 1.7 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CAMSAP_CC1 PF17095.5 GAN02097.1 - 0.32 10.9 2.1 0.61 10.0 2.1 1.3 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin BBP1_N PF15271.6 GAN02097.1 - 8 7.2 8.1 3.8 8.3 0.2 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein RhoGEF PF00621.20 GAN02098.1 - 1.6e-32 113.2 1.8 2.7e-32 112.5 1.8 1.4 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 GAN02098.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 PH domain Oxysterol_BP PF01237.18 GAN02099.1 - 1.2e-70 238.3 1.1 2.4e-63 214.2 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein CPL PF08144.11 GAN02100.1 - 4.9e-42 143.7 8.6 2.1e-41 141.6 0.9 4.5 4 2 2 6 6 6 1 CPL (NUC119) domain PUF PF00806.19 GAN02100.1 - 1e-06 28.1 0.0 5.1 7.0 0.0 5.8 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat DUF1744 PF08490.12 GAN02101.1 - 1.8e-138 461.5 0.2 2.7e-138 460.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 GAN02101.1 - 2.6e-77 260.2 3.2 5.1e-77 259.3 1.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GAN02101.1 - 2e-14 53.2 3.0 3.2e-12 45.9 0.1 3.9 4 1 0 4 4 4 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 GAN02101.1 - 2.8e-09 37.0 0.3 7.5e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAN02101.1 - 1e-05 25.6 0.1 6e-05 23.1 0.1 2.4 1 0 0 1 1 1 1 RNase_H superfamily 7TMR-HDED PF07697.11 GAN02101.1 - 0.15 12.2 0.9 2.7 8.1 0.2 2.9 2 0 0 2 2 2 0 7TM-HD extracellular Cytochrome_C7 PF14522.6 GAN02101.1 - 0.24 11.4 12.0 0.0071 16.3 5.5 1.9 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF4379 PF14311.6 GAN02101.1 - 3.6 8.0 5.6 5.8 7.4 2.0 2.6 1 1 1 2 2 2 0 Probable Zinc-ribbon domain RNA_pol_Rpb1_1 PF04997.12 GAN02102.1 - 2.4e-92 309.6 0.0 3.9e-92 308.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAN02102.1 - 7.3e-84 281.3 0.7 1.1e-83 280.8 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAN02102.1 - 1e-73 247.1 0.1 2.9e-73 245.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAN02102.1 - 6.4e-38 130.2 0.0 6.1e-37 127.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAN02102.1 - 2.4e-31 107.8 0.3 8e-31 106.2 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Melibiase PF02065.18 GAN02103.1 - 5.7e-19 68.3 0.2 9.5e-19 67.5 0.2 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.26 GAN02103.1 - 3.9e-07 29.6 0.1 1.1e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 GAN02103.1 - 9.4e-07 28.3 0.1 0.0003 20.1 0.0 2.5 2 0 0 2 2 2 2 Alpha galactosidase A Raffinose_syn PF05691.12 GAN02103.1 - 0.039 11.7 0.1 0.062 11.1 0.1 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 PRANC PF09372.10 GAN02104.1 - 0.042 14.2 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 PRANC domain DUF4301 PF14134.6 GAN02104.1 - 0.19 10.5 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) PH PF00169.29 GAN02105.1 - 2.5e-24 85.8 7.5 5.8e-24 84.6 1.6 3.6 4 0 0 4 4 4 1 PH domain SAM_2 PF07647.17 GAN02105.1 - 5.5e-17 61.6 0.0 1.9e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 GAN02105.1 - 2.2e-12 46.6 0.0 5.1e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 GAN02105.1 - 3e-12 46.8 0.0 7.1e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 GAN02105.1 - 1.1e-11 44.1 0.1 2.1e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain CH PF00307.31 GAN02105.1 - 5.9e-08 32.9 0.1 2.3e-07 31.0 0.0 2.0 2 1 0 2 2 2 1 Calponin homology (CH) domain PH_11 PF15413.6 GAN02105.1 - 6.8e-07 29.7 9.5 1.2e-06 28.9 6.1 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.17 GAN02105.1 - 9.9e-06 25.2 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 GAN02105.1 - 0.00022 21.4 2.8 0.0006 20.0 1.7 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain NRIP1_repr_4 PF15690.5 GAN02105.1 - 0.005 16.2 3.4 0.011 15.1 3.4 1.5 1 0 0 1 1 1 1 Nuclear receptor-interacting protein 1 repression 4 PH_9 PF15410.6 GAN02105.1 - 0.037 14.4 1.1 0.14 12.6 0.3 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Spt5_N PF11942.8 GAN02105.1 - 0.76 10.8 3.9 0.42 11.6 1.4 1.9 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_hydro_18 PF00704.28 GAN02106.1 - 6.4e-18 65.5 0.0 8.8e-18 65.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LETM1 PF07766.13 GAN02107.1 - 5.3e-106 353.9 5.2 5.3e-106 353.9 5.2 2.3 2 0 0 2 2 2 1 LETM1-like protein Na_trans_assoc PF06512.13 GAN02107.1 - 0.26 11.6 9.2 0.04 14.2 3.5 2.2 2 1 0 2 2 2 0 Sodium ion transport-associated CPSF100_C PF13299.6 GAN02107.1 - 4.7 7.4 13.9 1.2 9.3 8.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Aldedh PF00171.22 GAN02109.1 - 1.5e-165 551.2 0.4 1.8e-165 551.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ssu72 PF04722.13 GAN02110.1 - 0.023 14.3 0.2 0.044 13.3 0.2 1.5 1 0 0 1 1 1 0 Ssu72-like protein FTR_C PF02741.15 GAN02110.1 - 0.069 13.2 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 FTR, proximal lobe zf-RVT PF13966.6 GAN02111.1 - 0.0013 19.4 1.1 0.0029 18.3 1.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.6 GAN02112.1 - 5e-10 39.3 0.0 6.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 GAN02113.1 - 2.5e-62 205.3 22.0 3e-10 40.5 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02113.1 - 5e-22 78.0 3.0 0.00014 22.1 0.0 6.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN02113.1 - 9.4e-12 45.2 2.4 2.4e-06 27.6 0.0 4.2 3 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAN02113.1 - 2.1e-10 39.9 9.5 0.0049 15.6 0.0 5.6 2 1 5 7 7 7 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN02113.1 - 4e-06 26.0 3.1 0.1 11.6 0.7 4.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAN02113.1 - 7.8e-06 25.4 0.1 0.002 17.5 0.0 2.9 2 1 2 4 4 4 2 WD40-like domain PALB2_WD40 PF16756.5 GAN02113.1 - 0.00029 19.9 4.5 1.1 8.1 0.0 4.1 2 1 3 5 5 5 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 GAN02113.1 - 0.00077 17.9 0.2 0.0042 15.5 0.0 2.2 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 GAN02113.1 - 0.05 13.6 1.1 2.4 8.2 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 GAN02113.1 - 0.053 12.6 0.0 0.33 10.0 0.0 2.1 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain PBP-Tp47_a PF14889.6 GAN02113.1 - 0.13 11.9 0.4 0.29 10.7 0.4 1.5 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a FAM176 PF14851.6 GAN02113.1 - 0.26 10.9 3.0 5.2 6.7 0.1 2.7 2 0 0 2 2 2 0 FAM176 family Ank_2 PF12796.7 GAN02114.1 - 1.7e-20 73.4 1.5 4.7e-09 36.7 0.1 3.1 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN02114.1 - 3.6e-19 68.9 0.9 6.7e-09 36.1 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN02114.1 - 7.6e-18 62.8 4.5 3.6e-06 26.9 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAN02114.1 - 1.6e-13 50.4 5.6 1.2e-05 25.6 0.2 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 GAN02114.1 - 5.5e-13 48.9 5.8 4.9e-07 29.9 0.0 4.1 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ribosomal_S4Pg PF11993.8 GAN02114.1 - 0.03 14.4 0.1 0.089 12.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal S4P (gammaproteobacterial) Lactamase_B_2 PF12706.7 GAN02115.1 - 1.8e-31 109.3 0.0 3.2e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAN02115.1 - 3.7e-14 52.9 0.0 6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAN02115.1 - 0.00039 20.5 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily DEAD PF00270.29 GAN02116.1 - 1e-38 132.9 0.1 5e-38 130.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN02116.1 - 6.8e-21 74.7 0.1 3.1e-20 72.6 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 GAN02116.1 - 0.00036 20.3 0.1 0.00057 19.7 0.1 1.3 1 0 0 1 1 1 1 HIT zinc finger Noc2 PF03715.13 GAN02117.1 - 5.5e-103 344.3 2.7 5.5e-103 344.3 2.7 2.4 3 0 0 3 3 3 1 Noc2p family Pecanex_C PF05041.15 GAN02117.1 - 0.022 14.4 1.6 0.68 9.5 0.6 2.3 2 0 0 2 2 2 0 Pecanex protein (C-terminus) DUF5024 PF16427.5 GAN02117.1 - 5.9 7.3 10.4 1.3 9.4 5.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) Pkinase PF00069.25 GAN02118.1 - 1.3e-73 247.6 0.0 2e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02118.1 - 1.3e-37 129.5 0.0 2.2e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN02118.1 - 9.2e-05 21.9 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN02118.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase_3 PF08282.12 GAN02120.1 - 2.4 7.8 7.2 2.5 7.8 3.8 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase EMP70 PF02990.16 GAN02121.1 - 3.3e-143 478.1 15.6 4.1e-143 477.8 15.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Aminotran_1_2 PF00155.21 GAN02121.1 - 4.3e-63 213.7 0.0 5.7e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAN02121.1 - 0.001 17.7 0.0 0.0035 15.9 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAN02121.1 - 0.0029 17.0 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CrgA PF06781.12 GAN02121.1 - 0.0034 17.4 0.3 0.024 14.7 0.1 2.4 2 0 0 2 2 2 1 Cell division protein CrgA Beta_elim_lyase PF01212.21 GAN02121.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 GAN02121.1 - 0.035 13.1 0.0 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V DUF5079 PF16882.5 GAN02121.1 - 0.063 13.2 5.6 0.4 10.5 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) LysM PF01476.20 GAN02124.1 - 5.7e-11 42.3 0.8 0.0002 21.4 0.1 3.3 3 0 0 3 3 3 2 LysM domain Stn1 PF10451.9 GAN02125.1 - 0.00067 18.7 0.1 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 GAN02125.1 - 0.009 16.0 0.2 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 GAN02125.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 PDEase_I PF00233.19 GAN02126.1 - 1.5e-69 234.3 0.1 3.5e-69 233.2 0.1 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 GAN02126.1 - 0.095 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 HD domain ChaC PF04752.12 GAN02126.1 - 0.19 11.8 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 ChaC-like protein RGS PF00615.19 GAN02127.1 - 4.1e-13 49.6 0.5 9.7e-13 48.4 0.5 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain KH_1 PF00013.29 GAN02128.1 - 1e-12 47.7 0.0 7.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 GAN02128.1 - 0.025 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 KH domain Pribosyltran_N PF13793.6 GAN02129.1 - 1.4e-47 160.4 1.3 3.4e-46 156.0 0.2 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAN02129.1 - 7.7e-43 146.7 4.4 3.5e-36 124.9 0.9 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAN02129.1 - 6e-15 55.1 1.0 9e-14 51.3 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAN02129.1 - 0.034 13.6 0.2 0.063 12.7 0.2 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ABC_tran PF00005.27 GAN02131.1 - 7.4e-36 123.7 0.4 2e-35 122.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 GAN02131.1 - 6e-33 114.7 11.8 6e-33 114.7 11.8 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region MTABC_N PF16185.5 GAN02131.1 - 4.5e-11 42.7 7.6 3e-10 40.0 7.6 2.3 1 1 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 GAN02131.1 - 2.2e-07 30.6 0.1 9.5e-06 25.2 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAN02131.1 - 0.0034 17.8 0.1 0.014 15.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAN02131.1 - 0.01 15.6 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN02131.1 - 0.013 15.8 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAN02131.1 - 0.023 14.6 0.4 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_21 PF13304.6 GAN02131.1 - 0.039 13.8 0.2 0.21 11.4 0.1 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 GAN02131.1 - 0.049 13.7 0.0 0.5 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0240 PF06784.11 GAN02132.1 - 7.5e-06 26.1 0.7 7.5e-06 26.1 0.7 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0240) DUF4296 PF14129.6 GAN02132.1 - 0.018 15.6 0.3 0.042 14.5 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4296) USP8_interact PF08941.10 GAN02133.1 - 0.015 15.1 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 USP8 interacting MFS_1 PF07690.16 GAN02134.1 - 3.1e-38 131.6 60.8 3.4e-30 105.2 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RhoGEF PF00621.20 GAN02135.1 - 8.9e-26 91.2 3.3 2e-25 90.1 3.3 1.6 1 0 0 1 1 1 1 RhoGEF domain Acetyltransf_1 PF00583.25 GAN02136.1 - 5.3e-07 29.9 0.0 1.5e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Retrotran_gag_3 PF14244.6 GAN02136.1 - 0.053 13.3 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Acetyltransf_10 PF13673.7 GAN02136.1 - 0.06 13.3 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN02136.1 - 0.17 12.3 0.0 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sld5 PF05916.11 GAN02137.1 - 1.1e-10 42.0 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Asp PF00026.23 GAN02138.1 - 8e-70 235.7 0.6 1e-69 235.4 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_S24e PF01282.19 GAN02138.1 - 1.6e-35 120.9 2.0 2e-35 120.6 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S24e TAXi_N PF14543.6 GAN02138.1 - 4.8e-17 62.8 0.0 4.6e-08 33.5 0.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN02138.1 - 0.00038 21.0 0.0 0.85 10.3 0.0 3.3 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 GAN02138.1 - 0.0005 19.9 0.0 0.0022 17.8 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 GAN02138.1 - 0.00068 20.1 0.0 0.61 10.7 0.0 3.1 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease Cyclin_N PF00134.23 GAN02139.1 - 5.2e-13 48.8 0.6 1.3e-12 47.6 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Semialdhyde_dhC PF02774.18 GAN02140.1 - 7.5e-40 137.0 0.0 1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GAN02140.1 - 8.4e-31 106.9 0.0 1.4e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 GAN02140.1 - 0.0082 15.7 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 GAN02140.1 - 0.03 15.0 0.0 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ldh_1_N PF00056.23 GAN02140.1 - 0.073 13.2 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SURF4 PF02077.15 GAN02141.1 - 2.3e-76 256.9 6.6 1.3e-75 254.5 6.6 1.8 1 1 0 1 1 1 1 SURF4 family DUF624 PF04854.14 GAN02141.1 - 0.021 14.9 5.0 0.077 13.1 4.9 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF624 TraX PF05857.11 GAN02141.1 - 0.073 13.1 7.2 0.09 12.8 7.2 1.1 1 0 0 1 1 1 0 TraX protein PX PF00787.24 GAN02142.1 - 7.7e-18 64.5 0.5 1.7e-17 63.4 0.5 1.5 1 0 0 1 1 1 1 PX domain DUF2839 PF10999.8 GAN02142.1 - 0.14 12.5 0.1 0.42 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) DUF5320 PF17253.2 GAN02142.1 - 8.9 7.4 6.7 6.1 8.0 0.5 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5320) FAD-oxidase_C PF02913.19 GAN02143.1 - 3e-54 184.3 0.0 4.1e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAN02143.1 - 7.3e-32 110.0 0.0 1.1e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TBP PF00352.21 GAN02144.1 - 2.6e-68 226.0 0.1 1.6e-33 114.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 GAN02144.1 - 2.4e-05 24.3 0.0 0.18 11.9 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 GAN02144.1 - 0.049 13.4 0.1 0.22 11.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) SLC35F PF06027.12 GAN02145.1 - 2.7e-94 316.0 22.0 3.2e-94 315.8 22.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 GAN02145.1 - 2.4e-09 36.6 5.7 2.4e-09 36.6 5.7 1.8 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAN02145.1 - 7.8e-07 29.3 30.7 0.00069 19.8 12.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAN02145.1 - 0.00023 20.5 20.4 0.00032 20.0 20.4 1.2 1 0 0 1 1 1 1 UAA transporter family Iso_dh PF00180.20 GAN02146.1 - 2.5e-83 280.1 0.2 3.1e-83 279.8 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase V-set_2 PF15910.5 GAN02147.1 - 0.035 14.2 1.9 0.038 14.1 0.1 1.8 1 1 1 2 2 2 0 ICOS V-set domain eIF2A PF08662.11 GAN02148.1 - 3.1e-83 278.4 2.4 9.5e-80 267.1 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cys_box PF17869.1 GAN02148.1 - 0.034 14.3 0.3 0.069 13.3 0.3 1.4 1 0 0 1 1 1 0 Anosmin cysteine rich domain Cytochrom_D1 PF02239.16 GAN02148.1 - 0.057 11.9 0.0 2.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PMM PF03332.13 GAN02149.1 - 1.8e-109 364.6 0.3 2.1e-109 364.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GAN02149.1 - 0.00012 21.9 0.0 0.00053 19.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAN02149.1 - 0.019 14.5 0.0 0.97 8.9 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAN02149.1 - 0.13 12.6 0.0 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN02149.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Motile_Sperm PF00635.26 GAN02150.1 - 9.9e-05 22.2 0.0 0.00035 20.4 0.0 1.9 1 1 0 1 1 1 1 MSP (Major sperm protein) domain CCDC92 PF14916.6 GAN02150.1 - 0.02 14.6 0.2 0.044 13.6 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function AMP-binding PF00501.28 GAN02151.1 - 1.9e-77 260.7 0.0 2.2e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN02151.1 - 6.2e-21 75.2 0.0 1.1e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAN02151.1 - 5.7e-11 42.2 0.4 1.4e-10 40.9 0.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF2017 PF09438.10 GAN02152.1 - 0.053 13.4 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) CENP-B_dimeris PF09026.10 GAN02153.1 - 0.004 17.5 13.1 0.013 15.9 13.1 1.9 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Mlh1_C PF16413.5 GAN02153.1 - 0.016 14.6 0.9 0.023 14.1 0.1 1.6 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus TipE PF16972.5 GAN02153.1 - 0.072 12.3 9.9 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE TRAP_alpha PF03896.16 GAN02153.1 - 0.08 12.1 4.0 0.16 11.2 4.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 GAN02153.1 - 0.11 10.7 8.5 0.19 9.9 8.5 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAN02153.1 - 0.25 9.6 6.1 0.42 8.8 6.1 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GAN02153.1 - 0.36 10.1 14.0 0.61 9.3 14.0 1.3 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GAN02153.1 - 0.57 9.8 5.5 1.3 8.7 5.5 1.5 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 GAN02153.1 - 0.58 10.0 10.5 0.046 13.6 5.7 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 GAN02153.1 - 0.64 9.4 11.4 0.13 11.6 7.4 1.7 2 0 0 2 2 2 0 SDA1 RXT2_N PF08595.11 GAN02153.1 - 1.2 9.2 14.7 0.71 9.9 5.4 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal RPA43_OB PF17875.1 GAN02153.1 - 1.9 9.1 6.6 5 7.8 2.1 2.5 2 1 1 3 3 3 0 RPA43 OB domain in RNA Pol I PI3K_1B_p101 PF10486.9 GAN02153.1 - 2.4 5.8 5.8 4.2 5.0 2.7 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 GAN02153.1 - 3 6.9 20.7 4.7 6.2 20.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 GAN02153.1 - 3.4 8.1 13.4 2.1 8.8 10.3 2.3 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RPN2_C PF18004.1 GAN02153.1 - 6.4 6.7 8.1 4.1 7.3 1.8 2.4 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain FRQ PF09421.10 GAN02153.1 - 8 4.3 6.6 12 3.7 6.6 1.2 1 0 0 1 1 1 0 Frequency clock protein NUDE_C PF04880.13 GAN02155.1 - 1.4e-15 58.2 17.9 1.4e-15 58.2 17.9 2.5 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 GAN02155.1 - 0.00011 22.3 41.2 0.00071 19.6 6.7 3.4 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Filament PF00038.21 GAN02155.1 - 0.0067 16.0 6.2 0.0067 16.0 6.2 3.2 1 1 2 3 3 3 1 Intermediate filament protein PSII_Pbs27 PF13326.6 GAN02155.1 - 0.016 15.5 1.6 0.016 15.5 1.6 2.1 2 1 1 3 3 2 0 Photosystem II Pbs27 Peptidase_M61 PF05299.12 GAN02155.1 - 0.071 13.5 4.6 0.61 10.5 0.2 3.4 3 0 0 3 3 3 0 M61 glycyl aminopeptidase GAS PF13851.6 GAN02155.1 - 0.084 12.2 40.0 0.31 10.4 21.9 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2353 PF09789.9 GAN02155.1 - 0.11 11.8 35.2 0.21 10.9 22.0 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) BRE1 PF08647.11 GAN02155.1 - 0.23 11.5 30.2 2.7 8.1 19.6 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 GAN02155.1 - 0.24 8.9 33.5 0.32 8.4 33.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bap31_Bap29_C PF18035.1 GAN02155.1 - 0.37 10.8 11.1 2.6 8.1 2.2 2.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1664 PF07889.12 GAN02155.1 - 0.6 10.1 18.8 0.19 11.8 5.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Noelin-1 PF12308.8 GAN02155.1 - 1 9.4 15.1 0.18 11.8 7.4 3.0 3 1 0 3 3 3 0 Neurogenesis glycoprotein HOOK PF05622.12 GAN02155.1 - 1.1 7.3 40.2 0.22 9.6 14.1 2.2 1 1 1 2 2 2 0 HOOK protein kleA_kleC PF17383.2 GAN02155.1 - 1.4 9.3 6.3 0.25 11.7 0.6 2.6 2 2 1 3 3 3 0 Uncharacterized KorC regulated protein A Fib_alpha PF08702.10 GAN02155.1 - 1.5 9.0 25.8 0.13 12.5 13.8 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TACC_C PF05010.14 GAN02155.1 - 1.7 8.4 34.7 26 4.5 14.5 3.1 2 1 2 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF730 PF05325.11 GAN02155.1 - 2.1 8.4 9.0 0.15 12.1 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF730) DUF948 PF06103.11 GAN02155.1 - 2.8 8.3 8.0 46 4.4 4.4 3.0 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 GAN02155.1 - 4.8 7.2 42.9 0.73 9.9 10.3 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 GAN02155.1 - 4.9 8.1 35.6 0.55 11.2 11.8 3.9 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 GAN02155.1 - 5.5 6.0 30.6 0.061 12.4 16.1 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CALCOCO1 PF07888.11 GAN02155.1 - 7.6 5.3 37.4 6.9 5.4 35.0 1.9 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 GAN02155.1 - 7.6 6.9 34.6 54 4.2 21.0 2.4 1 1 1 2 2 2 0 Fez1 DUF3425 PF11905.8 GAN02156.1 - 1.2e-08 35.0 0.4 4.6e-08 33.1 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Radial_spoke_3 PF06098.11 GAN02156.1 - 0.017 14.4 4.1 0.041 13.2 4.1 1.6 1 0 0 1 1 1 0 Radial spoke protein 3 bZIP_2 PF07716.15 GAN02156.1 - 0.061 13.4 11.2 0.17 12.0 11.2 1.7 1 0 0 1 1 1 0 Basic region leucine zipper MAR_sialic_bdg PF10564.9 GAN02156.1 - 0.16 12.0 1.0 0.55 10.3 1.0 1.9 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat bZIP_Maf PF03131.17 GAN02156.1 - 0.18 12.4 10.6 0.84 10.2 10.6 2.1 1 0 0 1 1 1 0 bZIP Maf transcription factor DASH_Dad2 PF08654.10 GAN02157.1 - 3.2e-05 24.3 0.5 3.2e-05 24.3 0.5 1.8 1 1 1 2 2 2 1 DASH complex subunit Dad2 rhaM PF05336.13 GAN02157.1 - 0.042 13.9 0.4 0.058 13.5 0.4 1.3 1 0 0 1 1 1 0 L-rhamnose mutarotase YkyA PF10368.9 GAN02157.1 - 0.051 13.2 0.6 0.066 12.9 0.6 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein ESX-1_EspG PF14011.6 GAN02157.1 - 0.08 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 EspG family RRM_1 PF00076.22 GAN02158.1 - 3.9e-56 186.8 0.0 5.5e-19 67.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN02158.1 - 6.4e-05 22.9 0.0 0.19 11.8 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 GAN02158.1 - 0.0055 16.5 0.0 27 4.5 0.0 3.6 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 GAN02158.1 - 0.014 15.5 0.2 0.79 9.8 0.0 3.4 3 2 0 3 3 3 0 Limkain b1 RRM_occluded PF16842.5 GAN02158.1 - 0.03 14.2 0.0 32 4.5 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif RNase_H2_suC PF08615.11 GAN02159.1 - 2.4e-21 76.4 0.4 2.8e-21 76.2 0.4 1.0 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) OGG_N PF07934.12 GAN02159.1 - 0.016 15.3 0.2 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain ANAPC9 PF12856.7 GAN02159.1 - 0.019 15.2 0.6 0.019 15.2 0.6 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 DUF3164 PF11363.8 GAN02159.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) RXT2_N PF08595.11 GAN02160.1 - 0.6 10.1 6.8 1.2 9.1 5.3 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Drc1-Sld2 PF11719.8 GAN02160.1 - 0.66 9.5 12.8 0.98 8.9 12.8 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Cwf_Cwc_15 PF04889.12 GAN02160.1 - 8.6 6.0 13.4 14 5.4 13.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DPBB_1 PF03330.18 GAN02161.1 - 1.4e-11 44.5 0.8 6.3e-11 42.4 0.8 2.1 1 1 0 1 1 1 1 Lytic transglycolase Mucin PF01456.17 GAN02161.1 - 0.00045 20.2 13.1 0.00045 20.2 13.1 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Barwin PF00967.17 GAN02161.1 - 0.00081 19.2 0.9 0.0016 18.2 0.1 1.7 1 1 0 1 1 1 1 Barwin family Sporozoite_P67 PF05642.11 GAN02161.1 - 0.0082 14.3 5.9 0.0084 14.3 5.9 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4834 PF16118.5 GAN02161.1 - 0.056 14.4 0.0 0.12 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 GAN02161.1 - 0.063 12.9 0.5 0.097 12.3 0.5 1.3 1 0 0 1 1 1 0 FAM176 family Dicty_REP PF05086.12 GAN02161.1 - 0.097 10.6 5.7 0.11 10.5 5.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MAP65_ASE1 PF03999.12 GAN02161.1 - 0.25 10.0 4.1 0.27 9.9 4.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF572 PF04502.13 GAN02161.1 - 0.5 9.9 9.2 0.66 9.5 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Shisa PF13908.6 GAN02161.1 - 0.67 10.2 7.4 1.4 9.1 7.4 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Macoilin PF09726.9 GAN02161.1 - 1.3 7.5 4.8 1.4 7.3 4.8 1.0 1 0 0 1 1 1 0 Macoilin family Chitin_synth_2 PF03142.15 GAN02162.1 - 1.2e-243 809.5 0.1 2e-243 808.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAN02162.1 - 3.3e-119 399.1 7.0 4.4e-119 398.7 7.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 GAN02162.1 - 1.2e-15 57.4 0.0 3.1e-11 43.3 0.0 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 GAN02162.1 - 3.9e-14 53.1 0.0 2.1e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN02162.1 - 1.4e-12 48.0 2.9 4.2e-12 46.4 2.9 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAN02162.1 - 0.00012 21.9 0.0 0.021 14.6 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN02162.1 - 0.0099 15.4 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Fungal_trans PF04082.18 GAN02163.1 - 1.7e-05 24.0 0.0 3.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN02163.1 - 0.00088 19.4 12.0 0.0017 18.5 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTD_bind PF04818.13 GAN02164.1 - 3.7e-08 34.1 0.0 1e-07 32.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 GAN02164.1 - 8.8e-07 28.7 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 GAN02164.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 Ribosom_S12_S23 PF00164.25 GAN02165.1 - 2.7e-39 133.3 1.3 3.8e-39 132.8 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF1691 PF07950.11 GAN02166.1 - 3e-21 76.2 1.4 1e-16 61.6 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 GAN02166.1 - 0.01 15.8 0.9 0.01 15.8 0.9 2.6 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4405 PF14358.6 GAN02166.1 - 0.1 13.2 1.8 5.5 7.6 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) SecY PF00344.20 GAN02167.1 - 2.6e-67 227.3 9.8 3.4e-67 226.9 9.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAN02167.1 - 1.7e-17 62.9 0.5 4.1e-17 61.7 0.5 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p DUF4395 PF14340.6 GAN02167.1 - 0.99 9.7 5.1 1.6 9.1 3.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) DUF2408 PF10303.9 GAN02168.1 - 6.9e-27 94.6 4.1 2.5e-14 54.0 0.0 5.2 4 1 1 5 5 5 5 Protein of unknown function (DUF2408) Polysacc_deac_1 PF01522.21 GAN02169.1 - 1.8e-22 79.5 0.0 3.5e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase TAF PF02969.17 GAN02170.1 - 5.8e-31 106.5 1.0 1.7e-30 105.0 0.2 2.3 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 GAN02170.1 - 1e-30 105.9 0.0 2.8e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 GAN02170.1 - 0.00011 22.5 2.4 0.001 19.5 0.1 3.1 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAN02170.1 - 0.00016 21.8 0.0 0.00053 20.0 0.0 1.9 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 GAN02170.1 - 0.012 15.9 0.2 0.062 13.6 0.1 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT_EZ PF13513.6 GAN02170.1 - 0.014 15.9 0.0 1.1 9.8 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat TFIID_20kDa PF03847.13 GAN02170.1 - 0.026 15.0 0.3 0.14 12.7 0.2 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Telomere_reg-2 PF10193.9 GAN02170.1 - 0.062 13.7 4.2 4.2 7.9 0.1 3.4 3 1 1 4 4 4 0 Telomere length regulation protein Peptidase_C27 PF05407.12 GAN02170.1 - 0.17 12.0 0.3 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Rubella virus endopeptidase PLDc PF00614.22 GAN02171.1 - 6.3e-18 64.1 2.6 1.4e-10 40.9 0.1 3.0 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAN02171.1 - 4e-13 49.4 0.3 8.9e-06 25.6 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PX PF00787.24 GAN02171.1 - 3.9e-05 23.6 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 GAN02172.1 - 5.1e-65 213.8 30.5 4.2e-07 30.5 0.3 11.8 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 GAN02172.1 - 3.3e-54 182.7 0.4 5.6e-54 181.9 0.4 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 GAN02172.1 - 3.7e-19 68.8 11.7 0.0034 17.7 0.0 9.2 3 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN02172.1 - 1.8e-06 26.9 19.1 0.78 8.3 0.0 8.8 5 5 3 9 9 9 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN02172.1 - 2.2e-06 26.9 12.2 2.1 7.2 0.6 7.0 2 2 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAN02172.1 - 0.00034 20.0 8.4 0.35 10.1 0.0 6.0 2 2 3 5 5 5 1 WD40-like domain Cytochrom_D1 PF02239.16 GAN02172.1 - 0.0012 17.5 3.2 0.0028 16.2 0.3 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain VID27 PF08553.10 GAN02172.1 - 0.0018 17.4 1.0 0.28 10.2 0.0 2.9 3 0 0 3 3 3 2 VID27 C-terminal WD40-like domain Hira PF07569.11 GAN02172.1 - 0.0018 18.0 1.7 7.2 6.3 0.0 5.5 6 1 0 7 7 7 1 TUP1-like enhancer of split Utp12 PF04003.12 GAN02172.1 - 0.0022 18.2 0.0 0.0052 17.1 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family SdiA-regulated PF06977.11 GAN02172.1 - 0.0029 16.9 2.2 0.0052 16.1 0.1 2.5 3 0 0 3 3 3 1 SdiA-regulated Nucleoporin_N PF08801.11 GAN02172.1 - 0.0037 16.1 0.8 1.6 7.3 0.0 4.6 4 2 0 5 5 5 1 Nup133 N terminal like MMS1_N PF10433.9 GAN02173.1 - 3.9e-44 151.1 0.1 9.5e-38 130.0 0.1 2.7 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAN02173.1 - 2.4e-16 59.9 0.0 5.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region TFIIB PF00382.19 GAN02174.1 - 2.8e-35 120.2 2.2 6.1e-19 67.8 0.0 3.2 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GAN02174.1 - 9.7e-23 80.4 4.4 9.7e-23 80.4 4.4 3.4 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 GAN02174.1 - 2.5e-09 36.5 2.3 8e-09 34.9 2.3 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Alpha_L_fucos PF01120.17 GAN02175.1 - 4.5e-88 296.0 2.4 4.5e-88 296.0 2.4 1.5 2 0 0 2 2 2 1 Alpha-L-fucosidase Pkinase PF00069.25 GAN02176.1 - 1.1e-42 146.2 0.0 7.1e-24 84.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02176.1 - 6.3e-11 42.0 0.1 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ABC1 PF03109.16 GAN02176.1 - 0.1 12.8 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 ABC1 family DSPc PF00782.20 GAN02177.1 - 6.8e-07 29.2 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN02177.1 - 7.4e-05 22.4 0.0 9.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GAN02177.1 - 0.0021 17.8 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 GAN02177.1 - 0.046 13.8 0.0 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Inositol hexakisphosphate COX5B PF01215.19 GAN02177.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Sgf11 PF08209.11 GAN02178.1 - 1.3e-13 50.2 0.1 1.3e-13 50.2 0.1 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DZR PF12773.7 GAN02178.1 - 0.0077 16.2 2.2 0.017 15.1 2.2 1.6 1 0 0 1 1 1 1 Double zinc ribbon Opi1 PF08618.10 GAN02179.1 - 1.8e-53 182.3 13.3 1.9e-52 179.0 13.3 1.9 1 1 0 1 1 1 1 Transcription factor Opi1 DUF4055 PF13264.6 GAN02179.1 - 0.012 15.8 0.2 0.026 14.7 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) CCDC53 PF10152.9 GAN02179.1 - 0.1 13.0 3.1 0.12 12.8 0.1 2.4 1 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 GAN02179.1 - 7.7 7.2 8.0 0.26 11.9 0.9 2.1 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TH1 PF04858.13 GAN02180.1 - 4.3e-85 286.5 1.3 5.7e-85 286.1 1.3 1.0 1 0 0 1 1 1 1 TH1 protein DUF4078 PF13300.6 GAN02181.1 - 1.2e-23 83.3 11.4 1.2e-23 83.3 11.4 4.2 2 2 2 4 4 4 1 Domain of unknown function (DUF4078) SNF2_N PF00176.23 GAN02182.1 - 9.3e-65 218.6 3.7 1e-64 218.5 1.7 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 GAN02182.1 - 1.9e-24 85.3 3.3 7.6e-15 54.6 0.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GAN02182.1 - 1.4e-19 70.4 0.0 8.3e-19 68.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 GAN02182.1 - 2.7e-18 66.2 0.0 2.7e-18 66.2 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Cdh1_DBD_1 PF18196.1 GAN02182.1 - 5.8e-09 36.3 0.5 5.8e-09 36.3 0.5 6.8 5 2 1 6 6 6 1 Chromodomain helicase DNA-binding domain 1 Myb_DNA-binding PF00249.31 GAN02182.1 - 0.062 13.5 0.0 0.062 13.5 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain GWT1 PF06423.12 GAN02183.1 - 4e-36 124.4 1.9 4e-36 124.4 1.9 3.8 3 1 2 5 5 5 2 GWT1 DUF4405 PF14358.6 GAN02183.1 - 0.19 12.3 5.0 1.1 9.8 1.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) ArfGap PF01412.18 GAN02184.1 - 8.3e-40 135.5 0.2 8.3e-40 135.5 0.2 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 GAN02184.1 - 3.1e-11 42.9 0.1 0.00025 20.9 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain HOIP-UBA PF16678.5 GAN02184.1 - 3.8e-07 30.2 1.2 0.00084 19.4 0.2 2.5 2 0 0 2 2 2 2 HOIP UBA domain pair CUE PF02845.16 GAN02184.1 - 0.0018 17.9 0.0 0.75 9.6 0.0 3.0 2 0 0 2 2 2 2 CUE domain PAD_M PF08527.10 GAN02184.1 - 0.044 13.4 1.9 0.098 12.3 1.9 1.5 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Peptidase_M76 PF09768.9 GAN02185.1 - 9.6e-32 110.1 6.7 1.5e-31 109.4 6.7 1.3 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 GAN02185.1 - 0.008 16.0 0.2 0.014 15.3 0.1 1.6 2 0 0 2 2 2 1 SprT-like family Aspzincin_M35 PF14521.6 GAN02185.1 - 0.024 15.2 0.0 0.049 14.2 0.0 1.5 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase DIPSY PF11763.8 GAN02185.1 - 0.065 13.4 0.2 0.098 12.8 0.2 1.3 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Tox-MPTase2 PF15638.6 GAN02185.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 zf-RING_12 PF17976.1 GAN02185.1 - 0.23 11.8 2.9 0.43 10.9 2.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 GAN02187.1 - 8.4e-29 99.2 9.5 3.8e-08 33.9 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02187.1 - 4.1e-25 87.9 0.5 0.0045 17.3 0.0 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN02187.1 - 1.2e-10 41.6 0.8 4.8e-06 26.6 0.1 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAN02187.1 - 1e-07 31.6 0.1 0.027 13.8 0.0 3.5 3 1 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 GAN02187.1 - 0.00012 20.9 0.3 0.012 14.3 0.1 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 GAN02187.1 - 0.00031 20.6 0.8 0.87 9.6 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat VID27 PF08553.10 GAN02187.1 - 0.004 16.3 0.0 0.65 9.0 0.0 2.4 2 1 0 2 2 2 2 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 GAN02187.1 - 0.0044 15.6 0.2 0.67 8.4 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain IKI3 PF04762.12 GAN02187.1 - 0.0087 14.1 0.5 0.11 10.5 0.3 2.4 1 1 0 1 1 1 1 IKI3 family DUF1285 PF06938.11 GAN02187.1 - 0.14 12.2 0.0 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) Pho88 PF10032.9 GAN02188.1 - 1.9e-52 177.2 0.0 2e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Alk_phosphatase PF00245.20 GAN02189.1 - 5e-62 210.2 0.0 1.2e-61 208.9 0.0 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 GAN02189.1 - 4.2e-06 26.4 0.8 4.2e-06 26.4 0.8 2.7 3 1 0 3 3 3 1 Sulfatase Phosphodiest PF01663.22 GAN02189.1 - 1.4e-05 24.9 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase WD40 PF00400.32 GAN02191.1 - 2e-41 139.2 26.7 3.1e-05 24.6 0.0 13.3 13 1 0 13 13 13 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02191.1 - 2.1e-05 24.7 7.9 2.2 8.7 0.0 5.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CK2S PF15011.6 GAN02192.1 - 2.1e-33 115.5 4.4 3.2e-33 114.9 4.4 1.2 1 0 0 1 1 1 1 Casein Kinase 2 substrate Glu-tRNAGln PF02686.15 GAN02192.1 - 0.027 14.8 0.3 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Nrap PF03813.14 GAN02192.1 - 0.037 14.1 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Nrap protein domain 1 RasGEF_N PF00618.20 GAN02192.1 - 0.09 13.0 0.4 0.29 11.4 0.0 1.9 2 1 0 2 2 2 0 RasGEF N-terminal motif Med21 PF11221.8 GAN02192.1 - 0.13 12.5 5.1 0.67 10.2 5.2 2.0 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Med22 PF06179.12 GAN02192.1 - 0.39 11.0 4.5 0.29 11.4 0.9 2.1 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex Ribosomal_L2 PF00181.23 GAN02193.1 - 3e-12 46.3 0.1 3.6e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain BolA PF01722.18 GAN02194.1 - 3.1e-14 53.0 0.0 1e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein DUF2415 PF10313.9 GAN02195.1 - 4.6e-08 32.9 0.0 1.9e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 GAN02195.1 - 8.6e-08 32.4 0.0 0.0026 18.0 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN02195.1 - 0.0042 17.9 0.1 2.6 9.1 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Frtz PF11768.8 GAN02195.1 - 0.01 14.2 0.1 0.019 13.3 0.1 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1604 PF07713.13 GAN02196.1 - 4.5e-38 129.0 1.9 4.5e-38 129.0 1.9 4.8 5 1 1 6 6 6 1 Protein of unknown function (DUF1604) G-patch PF01585.23 GAN02196.1 - 2.7e-08 33.6 0.0 7.7e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN02196.1 - 0.00034 20.6 0.3 0.0067 16.5 0.2 3.3 2 1 0 2 2 2 1 G-patch domain Aminotran_1_2 PF00155.21 GAN02197.1 - 6.3e-75 252.6 0.0 7.6e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAN02197.1 - 1.3e-06 27.3 0.0 1.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAN02197.1 - 7.4e-05 21.9 0.0 0.00031 19.8 0.0 2.0 1 1 1 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAN02197.1 - 0.0012 18.2 0.0 0.0031 16.8 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Preseq_ALAS PF09029.10 GAN02197.1 - 0.0014 19.1 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.17 GAN02197.1 - 0.15 11.4 0.1 0.45 9.8 0.1 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SLX9 PF15341.6 GAN02198.1 - 5.2e-19 68.9 19.0 6.3e-19 68.7 17.7 1.8 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Acyl-CoA_dh_1 PF00441.24 GAN02199.1 - 7.7e-34 117.1 0.9 1.4e-33 116.3 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 GAN02199.1 - 9.4e-21 73.8 0.0 2e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 GAN02199.1 - 3.6e-17 62.3 0.2 6e-17 61.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAN02199.1 - 1.7e-11 44.8 0.0 3.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAN02199.1 - 1e-06 29.0 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PIF1 PF05970.14 GAN02201.1 - 3.4e-41 141.6 0.3 1.8e-20 73.4 0.0 2.4 3 0 0 3 3 3 2 PIF1-like helicase TMV_coat PF00721.21 GAN02203.1 - 0.15 11.9 5.7 0.16 11.8 5.7 1.2 1 0 0 1 1 1 0 Virus coat protein (TMV like) Chitin_synth_2 PF03142.15 GAN02204.1 - 7.9e-93 311.9 4.9 8.9e-72 242.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 GAN02204.1 - 0.0015 18.4 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 XAP5 PF04921.14 GAN02204.1 - 0.62 9.9 3.1 1.2 8.9 3.1 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3246 PF11596.8 GAN02204.1 - 2.2 7.6 13.9 0.11 11.9 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Cyclin PF08613.11 GAN02205.1 - 1.3e-05 25.6 14.0 1.3e-05 25.6 14.0 4.2 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAN02205.1 - 0.017 14.8 0.8 0.017 14.8 0.8 2.8 2 1 0 2 2 2 0 Cyclin, N-terminal domain Patatin PF01734.22 GAN02205.1 - 0.038 14.2 0.5 0.11 12.7 0.1 2.0 1 1 0 1 1 1 0 Patatin-like phospholipase RRM_1 PF00076.22 GAN02206.1 - 2.6e-11 43.1 0.0 1.1e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 GAN02206.1 - 1.4e-09 37.1 2.1 2e-09 36.6 2.1 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1690 PF07956.11 GAN02208.1 - 1.1e-28 100.4 6.2 1.3e-28 100.1 6.2 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lipoprotein_2 PF00921.17 GAN02208.1 - 0.037 13.6 4.0 0.053 13.1 4.0 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein CHCH PF06747.13 GAN02208.1 - 0.052 13.7 0.3 0.11 12.7 0.3 1.6 1 0 0 1 1 1 0 CHCH domain COMPASS-Shg1 PF05205.12 GAN02208.1 - 0.13 13.0 4.2 0.22 12.2 4.2 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 tRNA-synt_1 PF00133.22 GAN02209.1 - 4.3e-40 137.6 2.0 1.5e-29 102.7 0.2 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAN02209.1 - 7.4e-16 57.9 0.5 1.2e-09 37.5 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAN02209.1 - 8.6e-10 38.8 0.3 1.9e-09 37.7 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAN02209.1 - 7.9e-08 32.0 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Kelch_3 PF13415.6 GAN02210.1 - 2.3e-07 30.9 10.6 0.0013 19.0 0.2 5.9 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN02210.1 - 5.8e-07 29.2 2.7 0.19 11.7 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 GAN02210.1 - 3.8e-06 27.0 13.7 0.098 13.0 0.3 6.2 6 1 0 6 6 6 3 Kelch motif Adeno_E3_CR2 PF02439.15 GAN02210.1 - 2e-05 24.2 0.2 3.7e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Kelch_5 PF13854.6 GAN02210.1 - 2.1e-05 24.4 0.4 0.0058 16.6 0.0 3.7 4 0 0 4 4 4 1 Kelch motif UPF0560 PF10577.9 GAN02210.1 - 0.00019 20.1 0.0 0.00028 19.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 Kelch_1 PF01344.25 GAN02210.1 - 0.00051 19.6 12.3 1.2 8.8 0.0 6.0 5 1 0 5 5 5 2 Kelch motif SKG6 PF08693.10 GAN02210.1 - 0.33 10.4 3.1 0.92 9.0 3.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sulfotransfer_4 PF17784.1 GAN02211.1 - 0.024 14.4 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Z1 PF10593.9 GAN02211.1 - 0.33 10.4 5.1 0.45 10.0 5.1 1.4 1 1 0 1 1 1 0 Z1 domain MFS_1 PF07690.16 GAN02212.1 - 1.3e-35 123.0 50.9 1.2e-23 83.6 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PPTA PF01239.22 GAN02213.1 - 2.4e-12 46.1 21.2 4.7e-07 29.3 1.1 5.3 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat SWIRM-assoc_2 PF16496.5 GAN02214.1 - 3.9e-55 187.4 12.6 3.9e-55 187.4 12.6 1.8 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 GAN02214.1 - 1.3e-17 63.9 0.0 3.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAN02214.1 - 5.6e-11 42.2 2.8 1.4e-10 41.0 2.8 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GAN02214.1 - 9.6e-11 41.7 0.0 2.4e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN02214.1 - 7.6e-07 29.3 0.2 2.4e-06 27.7 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 GAN02214.1 - 0.00043 20.0 2.7 0.00075 19.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type YL1 PF05764.13 GAN02214.1 - 0.0041 17.3 16.0 0.0041 17.3 16.0 2.4 2 0 0 2 2 2 1 YL1 nuclear protein SANT_DAMP1_like PF16282.5 GAN02214.1 - 0.013 15.7 0.2 0.063 13.5 0.2 2.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 PPP4R2 PF09184.11 GAN02215.1 - 2.7e-20 73.2 25.0 5.9e-20 72.0 25.0 1.6 1 1 0 1 1 1 1 PPP4R2 Integrase_H2C2 PF17921.1 GAN02216.1 - 2.8e-08 33.7 0.4 2.8e-08 33.7 0.4 3.0 3 1 1 4 4 4 1 Integrase zinc binding domain Apolipo_F PF15148.6 GAN02216.1 - 0.13 11.8 0.3 0.34 10.4 0.2 1.7 2 0 0 2 2 2 0 Apolipoprotein F BRCT_2 PF16589.5 GAN02217.1 - 2.3e-10 40.7 0.7 6.2e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4_2 PF13923.6 GAN02217.1 - 6.1e-09 35.6 8.2 6.1e-09 35.6 8.2 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN02217.1 - 5.7e-08 32.5 9.6 1.7e-07 31.0 9.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAN02217.1 - 2.5e-05 24.0 3.7 5.7e-05 22.9 3.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RTT107_BRCT_5 PF16770.5 GAN02217.1 - 4.8e-05 23.2 1.5 0.00015 21.6 0.6 2.3 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_2 PF13639.6 GAN02217.1 - 0.00012 22.3 11.8 0.00012 22.3 11.8 2.4 2 0 0 2 2 2 1 Ring finger domain BRCT PF00533.26 GAN02217.1 - 0.00024 21.4 8.0 0.00051 20.4 0.1 3.6 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_3 PF13920.6 GAN02217.1 - 0.00025 20.8 10.3 0.00025 20.8 10.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN02217.1 - 0.0016 18.4 5.2 0.0049 16.9 5.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAN02217.1 - 0.0031 17.3 3.2 0.0031 17.3 3.2 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAN02217.1 - 0.0035 17.6 7.0 0.0035 17.6 7.0 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN02217.1 - 0.0043 17.0 12.8 0.0043 17.0 12.8 2.9 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN02217.1 - 0.0079 16.0 7.7 0.0079 16.0 7.7 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAN02217.1 - 0.0089 16.2 10.8 0.034 14.3 10.8 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-met2 PF12907.7 GAN02217.1 - 0.31 11.2 4.3 0.27 11.4 0.7 2.5 2 0 0 2 2 2 0 Zinc-binding LIG3_BRCT PF16759.5 GAN02217.1 - 0.61 10.4 3.4 20 5.6 0.3 2.9 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain zf-RING_10 PF16685.5 GAN02217.1 - 0.9 9.7 13.0 0.39 10.9 5.7 2.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 GAN02217.1 - 1 9.1 4.4 2.8 7.8 4.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-P11 PF03854.14 GAN02217.1 - 1.3 8.7 6.2 1.3 8.8 4.0 2.1 2 0 0 2 2 1 0 P-11 zinc finger DZR PF12773.7 GAN02217.1 - 2.6 8.2 17.0 5.9 7.0 1.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon CLTH PF10607.9 GAN02218.1 - 1e-27 96.9 0.8 2.6e-26 92.3 0.3 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 GAN02218.1 - 1.5e-26 92.9 0.4 2.8e-26 92.0 0.4 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 GAN02218.1 - 0.0034 17.3 0.1 0.009 15.9 0.1 1.8 1 0 0 1 1 1 1 LisH BK_channel_a PF03493.18 GAN02219.1 - 7.2e-25 87.0 0.3 8e-24 83.7 0.0 2.7 3 0 0 3 3 3 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 GAN02219.1 - 1.6e-12 47.2 5.8 4.1e-12 45.9 5.8 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 GAN02219.1 - 0.0012 18.2 11.7 0.0026 17.0 11.7 1.5 1 0 0 1 1 1 1 Ion transport protein WTF PF03303.13 GAN02219.1 - 0.006 16.3 0.2 0.016 14.9 0.2 1.7 1 0 0 1 1 1 1 WTF protein TrkA_N PF02254.18 GAN02219.1 - 0.011 15.9 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Castor_Poll_mid PF06241.12 GAN02219.1 - 0.034 14.1 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel DUF4666 PF15697.5 GAN02219.1 - 2.2 9.0 7.1 0.23 12.1 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Ribosomal_S25 PF03297.15 GAN02220.1 - 2.8e-39 133.4 2.3 4.2e-39 132.8 2.3 1.2 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 GAN02220.1 - 0.033 13.8 0.4 0.056 13.0 0.4 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 GAN02220.1 - 0.036 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 MarR family AIPR PF10592.9 GAN02220.1 - 0.051 13.2 0.4 0.068 12.8 0.4 1.4 1 1 0 1 1 1 0 AIPR protein bZIP_1 PF00170.21 GAN02221.1 - 2.3e-09 37.2 14.0 7.2e-09 35.6 14.0 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN02221.1 - 8.3e-05 22.6 21.7 0.00012 22.1 16.5 3.1 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAN02221.1 - 0.0024 18.4 8.7 0.0024 18.4 8.7 2.8 3 0 0 3 3 2 1 bZIP Maf transcription factor ERM PF00769.19 GAN02221.1 - 0.0035 17.2 8.1 0.0035 17.2 8.1 1.9 2 1 0 2 2 2 1 Ezrin/radixin/moesin family ZapB PF06005.12 GAN02221.1 - 0.0071 16.8 4.0 0.0071 16.8 4.0 2.7 4 0 0 4 4 2 1 Cell division protein ZapB CCDC92 PF14916.6 GAN02221.1 - 0.0081 15.9 0.1 0.0081 15.9 0.1 2.5 3 0 0 3 3 2 1 Coiled-coil domain of unknown function FlaC_arch PF05377.11 GAN02221.1 - 0.011 16.1 1.9 0.011 16.1 1.9 2.2 3 0 0 3 3 1 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 GAN02221.1 - 0.027 12.4 2.8 0.051 11.5 2.8 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_lysis PF03245.13 GAN02221.1 - 0.028 14.5 0.7 0.057 13.5 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Tnp_22_trimer PF17489.2 GAN02221.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.2 2 0 0 2 2 1 0 L1 transposable element trimerization domain PikAIV_N PF18605.1 GAN02221.1 - 0.3 10.7 3.5 0.65 9.6 3.5 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HALZ PF02183.18 GAN02221.1 - 0.57 10.4 5.7 15 5.9 4.0 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper CCDC-167 PF15188.6 GAN02221.1 - 0.72 10.2 6.0 2.8 8.3 6.0 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 XhlA PF10779.9 GAN02221.1 - 0.9 9.8 5.4 2.8 8.2 5.4 1.8 1 0 0 1 1 1 0 Haemolysin XhlA CENP-H PF05837.12 GAN02221.1 - 1.4 9.3 10.8 0.13 12.7 4.3 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Paramyxo_ncap PF00973.19 GAN02221.1 - 2.3 7.1 7.7 3.7 6.4 7.7 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein YabA PF06156.13 GAN02221.1 - 2.4 8.8 6.8 0.72 10.5 2.0 2.7 2 1 0 2 2 2 0 Initiation control protein YabA CASP_C PF08172.12 GAN02221.1 - 2.7 7.3 15.9 8.1 5.7 15.6 2.0 1 1 0 1 1 1 0 CASP C terminal Fib_alpha PF08702.10 GAN02221.1 - 4.4 7.5 11.3 7.4 6.7 7.1 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5094 PF17015.5 GAN02221.1 - 5.6 7.0 17.9 0.8 9.8 12.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5094) TMF_DNA_bd PF12329.8 GAN02221.1 - 6.6 6.8 13.2 6.6 6.8 9.9 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YjeF_N PF03853.15 GAN02222.1 - 2e-21 76.6 0.0 2.5e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus YjeF_N PF03853.15 GAN02223.1 - 0.00042 20.2 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus AMP-binding PF00501.28 GAN02224.1 - 1.8e-97 326.6 0.2 2.3e-97 326.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN02224.1 - 1.5e-22 80.4 0.1 3.8e-22 79.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAN02224.1 - 3.5e-16 58.9 2.7 7.1e-16 57.9 1.2 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus NAD_binding_10 PF13460.6 GAN02224.1 - 0.078 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding EC042_2821 PF18740.1 GAN02224.1 - 0.22 11.4 0.1 0.38 10.6 0.1 1.3 1 0 0 1 1 1 0 EC042_2821-lke REase Xpo1 PF08389.12 GAN02225.1 - 1.9e-27 96.2 0.5 1.3e-26 93.5 0.1 2.8 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 GAN02225.1 - 7.9e-11 41.7 1.7 1.5e-08 34.5 0.2 2.9 2 0 0 2 2 2 2 Importin-beta N-terminal domain Importin_rep PF18773.1 GAN02225.1 - 0.016 14.9 0.2 0.038 13.7 0.2 1.7 1 0 0 1 1 1 0 Importin 13 repeat AA_permease PF00324.21 GAN02226.1 - 4.1e-126 421.4 45.4 5.1e-126 421.1 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN02226.1 - 1e-46 159.7 47.5 1.2e-46 159.4 47.5 1.1 1 0 0 1 1 1 1 Amino acid permease ParG PF09274.10 GAN02226.1 - 0.11 12.7 0.2 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 ParG Androgen_recep PF02166.16 GAN02227.1 - 0.048 12.5 9.0 0.06 12.2 9.0 1.2 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 GAN02227.1 - 0.48 10.4 24.1 0.56 10.1 24.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM174 PF15029.6 GAN02227.1 - 2.9 7.5 12.4 3.7 7.2 11.8 1.4 2 0 0 2 2 2 0 Transmembrane protein 174 Presenilin PF01080.17 GAN02227.1 - 7.4 5.2 12.3 7.7 5.2 12.3 1.3 1 0 0 1 1 1 0 Presenilin ASD2 PF08687.11 GAN02227.1 - 7.8 6.0 24.0 0.032 13.8 3.3 2.3 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 Arm PF00514.23 GAN02228.1 - 6.3e-24 83.2 7.3 3.4e-07 30.1 0.0 7.8 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAN02228.1 - 4.4e-13 49.4 4.8 0.0015 19.0 0.0 6.5 6 1 0 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 GAN02228.1 - 7.7e-13 48.7 3.6 1.5e-05 25.3 0.2 5.5 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 GAN02228.1 - 1.3e-08 34.4 9.3 0.045 14.0 0.0 7.4 8 0 0 8 8 8 2 HEAT repeat RICTOR_V PF14668.6 GAN02228.1 - 9.2e-06 25.8 0.1 0.042 14.1 0.0 4.8 4 2 3 7 7 7 1 Rapamycin-insensitive companion of mTOR, domain 5 IBB PF01749.20 GAN02228.1 - 0.00027 21.3 3.8 0.00027 21.3 3.8 3.1 4 0 0 4 4 4 1 Importin beta binding domain Adaptin_N PF01602.20 GAN02228.1 - 0.0028 16.3 0.3 1.3 7.5 0.1 3.4 1 1 3 4 4 4 2 Adaptin N terminal region TFCD_C PF12612.8 GAN02228.1 - 0.033 14.0 0.0 0.29 11.0 0.0 2.4 1 1 0 2 2 2 0 Tubulin folding cofactor D C terminal HEAT_PBS PF03130.16 GAN02228.1 - 0.12 13.1 0.2 1e+02 4.0 0.0 4.3 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat Pex24p PF06398.11 GAN02229.1 - 1.7e-33 116.1 8.0 1.7e-27 96.4 5.2 2.5 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin C1_1 PF00130.22 GAN02229.1 - 1e-10 41.4 7.3 2e-10 40.4 7.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RanBP PF00641.18 GAN02229.1 - 0.19 11.1 4.7 0.46 9.8 0.2 3.5 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Methyltransf_31 PF13847.6 GAN02230.1 - 1.2e-07 31.7 0.1 8.6e-07 28.9 0.0 2.3 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN02230.1 - 2.4e-07 30.8 0.0 5.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN02230.1 - 7.9e-05 23.3 0.0 0.00024 21.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAN02230.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN02230.1 - 0.001 19.8 0.1 0.005 17.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN02230.1 - 0.0077 16.9 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN02230.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 GAN02230.1 - 0.041 13.0 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent PrmA PF06325.13 GAN02230.1 - 0.045 13.1 2.4 0.11 11.8 0.0 2.5 2 1 1 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 GAN02230.1 - 0.052 13.0 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family MetW PF07021.12 GAN02230.1 - 0.056 13.0 0.2 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PagP PF07017.11 GAN02230.1 - 0.073 12.5 0.1 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 Antimicrobial peptide resistance and lipid A acylation protein PagP AviRa PF11599.8 GAN02230.1 - 0.075 12.5 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Motile_Sperm PF00635.26 GAN02231.1 - 1.2e-22 79.8 0.7 2.5e-22 78.8 0.7 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Acyltransferase PF01553.21 GAN02231.1 - 8.1e-17 61.1 0.0 1.5e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ASH PF15780.5 GAN02231.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Bystin PF05291.11 GAN02232.1 - 3.5e-73 246.4 6.8 4.6e-73 246.0 6.8 1.1 1 0 0 1 1 1 1 Bystin SNRNP27 PF08648.12 GAN02233.1 - 2.7e-29 101.0 0.9 6.4e-29 99.8 0.9 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Presenilin PF01080.17 GAN02233.1 - 6.6 5.4 6.5 9.7 4.8 6.5 1.2 1 0 0 1 1 1 0 Presenilin Pro_isomerase PF00160.21 GAN02234.1 - 1.3e-48 165.3 0.1 2.4e-48 164.4 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 GAN02234.1 - 1.2e-13 50.6 0.0 2.7e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN02234.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 GAN02234.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GAN02235.1 - 2.2e-08 33.8 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN02235.1 - 2.3e-05 24.4 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Aa_trans PF01490.18 GAN02236.1 - 1.1e-62 212.1 29.1 1.5e-62 211.6 29.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAN02236.1 - 0.0011 18.0 9.7 0.0011 18.0 9.7 3.2 3 0 0 3 3 3 3 Tryptophan/tyrosine permease family Smim3 PF17307.2 GAN02236.1 - 2.9 7.4 6.4 1.9 8.0 0.2 2.9 2 0 0 2 2 2 0 Small integral membrane protein 3 Methyltransf_25 PF13649.6 GAN02237.1 - 6.3e-09 36.4 0.0 1.5e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN02237.1 - 2.5e-08 34.4 0.0 5.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Arrestin_C PF02752.22 GAN02237.1 - 2.4e-06 28.0 0.4 6.5e-05 23.4 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Methyltransf_31 PF13847.6 GAN02237.1 - 1.3e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN02237.1 - 4.9e-05 24.0 0.0 0.00011 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Arrestin_N PF00339.29 GAN02237.1 - 0.0035 17.4 0.0 0.09 12.8 0.0 2.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Methyltransf_29 PF03141.16 GAN02237.1 - 0.0061 15.2 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 GAN02237.1 - 0.0063 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 GAN02237.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Sugar_tr PF00083.24 GAN02238.1 - 3.9e-52 177.6 21.2 5.1e-52 177.2 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN02238.1 - 5.3e-25 88.1 28.3 3.1e-16 59.3 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 GAN02238.1 - 0.0048 16.6 2.7 0.95 9.1 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) AAA_12 PF13087.6 GAN02239.1 - 1.9e-23 83.1 1.5 2.4e-23 82.8 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAN02239.1 - 2.6e-09 37.3 0.3 0.0015 18.4 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 GAN02239.1 - 3.5e-08 33.9 0.1 5.2e-07 30.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAN02239.1 - 3.2e-06 27.0 0.0 3.6e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain DapH_N PF08503.10 GAN02239.1 - 0.0068 16.6 0.0 0.065 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetrahydrodipicolinate succinyltransferase N-terminal Cas_Cas4 PF01930.17 GAN02239.1 - 0.023 14.8 0.4 0.21 11.7 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF83 AAA_22 PF13401.6 GAN02239.1 - 0.062 13.6 0.0 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 GAN02239.1 - 0.062 13.1 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Forkhead PF00250.18 GAN02240.1 - 6.7e-27 93.6 0.0 1.7e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain NIF PF03031.18 GAN02241.1 - 1e-46 158.5 0.0 1.7e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4199 PF13858.6 GAN02241.1 - 3.7 7.9 5.7 8.8 6.7 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Glucan_synthase PF02364.15 GAN02242.1 - 0 1297.5 0.0 0 1296.3 0.0 1.6 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GAN02242.1 - 6e-32 110.7 1.3 2.9e-31 108.5 1.3 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF2448 PF10476.9 GAN02242.1 - 0.52 10.1 3.1 0.28 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) DUF155 PF02582.14 GAN02244.1 - 4.7e-55 186.4 0.2 4.7e-55 186.4 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Arf PF00025.21 GAN02245.1 - 2.3e-71 238.9 0.6 2.5e-71 238.7 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAN02245.1 - 1.4e-12 47.9 0.0 1.9e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAN02245.1 - 1.7e-12 47.2 1.3 1.8e-06 27.4 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAN02245.1 - 4.7e-11 42.5 0.0 5.6e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAN02245.1 - 2.6e-10 40.0 0.0 3.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAN02245.1 - 3.1e-09 36.5 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN02245.1 - 1.7e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN02245.1 - 4.4e-05 23.1 0.0 0.00049 19.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 GAN02245.1 - 0.044 13.7 0.2 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 GAN02245.1 - 0.047 13.2 0.2 0.13 11.8 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 GAN02245.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Aa_trans PF01490.18 GAN02246.1 - 2.7e-73 247.0 40.0 3.4e-73 246.7 40.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAM163 PF15069.6 GAN02246.1 - 0.29 11.6 1.4 0.65 10.4 1.4 1.5 1 0 0 1 1 1 0 FAM163 family AAA_13 PF13166.6 GAN02247.1 - 0.051 12.2 44.5 0.23 10.1 22.0 2.0 1 1 1 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.12 GAN02247.1 - 0.7 10.0 56.5 1.2 9.2 17.3 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ApbA_C PF08546.11 GAN02247.1 - 0.8 9.9 6.2 1.5 9.0 3.3 2.8 1 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal HMMR_N PF15905.5 GAN02247.1 - 0.85 9.0 59.0 3.6 7.0 44.4 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SopA PF13981.6 GAN02247.1 - 0.86 10.0 7.2 0.47 10.9 3.0 2.5 1 1 1 2 2 2 0 SopA-like central domain PLC-beta_C PF08703.10 GAN02247.1 - 1.1 9.3 57.6 2.1 8.3 13.2 3.4 1 1 0 2 2 2 0 PLC-beta C terminal Fib_alpha PF08702.10 GAN02247.1 - 1.8 8.7 46.9 1.9 8.7 17.6 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 GAN02247.1 - 3.9 7.7 56.6 4.5 7.5 23.4 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 AIP3 PF03915.13 GAN02247.1 - 4.2 6.4 46.0 4 6.4 14.1 2.2 1 1 1 2 2 2 0 Actin interacting protein 3 CENP-F_leu_zip PF10473.9 GAN02247.1 - 5.1 7.1 60.2 0.07 13.2 21.9 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 GAN02247.1 - 5.2 7.7 59.4 3.7 8.2 14.9 4.2 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Uso1_p115_C PF04871.13 GAN02247.1 - 6.8 7.1 55.2 40 4.6 20.7 3.8 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 GAN02247.1 - 6.9 7.2 61.9 3 8.4 16.3 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region Cob_adeno_trans PF01923.18 GAN02247.1 - 7.7 6.6 28.6 0.97 9.6 1.2 3.7 1 1 1 2 2 1 0 Cobalamin adenosyltransferase Spc7 PF08317.11 GAN02247.1 - 8.4 5.2 56.7 16 4.3 36.9 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 GAN02247.1 - 9.2 6.3 40.3 4.4 7.4 10.6 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FAM184 PF15665.5 GAN02247.1 - 9.5 5.9 54.5 75 3.0 34.3 3.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B G-patch PF01585.23 GAN02248.1 - 5.3e-15 55.0 1.3 1.4e-14 53.7 1.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN02248.1 - 7.9e-07 29.1 1.5 7.9e-07 29.1 1.5 3.6 2 1 1 3 3 1 1 G-patch domain CDC45 PF02724.14 GAN02248.1 - 0.0088 14.4 22.8 0.011 14.1 22.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GAN02248.1 - 0.025 12.8 24.3 0.03 12.5 24.3 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GAN02248.1 - 0.03 14.2 23.9 0.043 13.7 23.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 GAN02248.1 - 0.041 13.8 25.3 0.056 13.4 25.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2052 PF09747.9 GAN02248.1 - 0.055 13.6 17.4 0.09 12.9 17.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SOBP PF15279.6 GAN02248.1 - 0.089 13.4 13.8 0.11 13.1 13.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Endostatin PF06482.11 GAN02248.1 - 0.095 12.2 5.2 0.1 12.0 5.2 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 GAN02248.1 - 0.16 11.2 13.0 0.19 10.9 13.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Red1 PF07964.11 GAN02248.1 - 0.22 9.7 26.1 0.25 9.5 26.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 RP-C_C PF11800.8 GAN02248.1 - 0.31 11.1 11.6 0.56 10.3 11.6 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region eIF-3c_N PF05470.12 GAN02248.1 - 0.44 8.8 16.2 0.46 8.7 16.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AF-4 PF05110.13 GAN02248.1 - 0.45 8.5 33.6 0.56 8.2 33.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PCM1_C PF15717.5 GAN02248.1 - 0.51 9.0 19.7 0.71 8.5 19.7 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus SAPS PF04499.15 GAN02248.1 - 0.57 8.9 13.6 0.75 8.5 13.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GAN02248.1 - 0.63 8.7 19.6 0.75 8.5 19.6 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 GAN02248.1 - 0.9 9.8 32.8 1.7 9.0 32.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.7 GAN02248.1 - 1.1 7.3 16.8 1.3 7.1 16.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 GAN02248.1 - 1.5 7.8 19.6 2 7.4 19.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 GAN02248.1 - 1.9 8.5 10.2 2.5 8.1 10.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 GAN02248.1 - 1.9 7.3 19.2 2.3 7.0 19.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 GAN02248.1 - 2 5.4 13.4 2.1 5.4 13.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 GAN02248.1 - 2.7 6.7 13.1 3.2 6.5 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NPR3 PF03666.13 GAN02248.1 - 2.9 6.6 23.5 3.7 6.2 23.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 O-antigen_lig PF13425.6 GAN02248.1 - 3.6 6.3 10.8 4.7 5.9 10.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein VIR_N PF15912.5 GAN02248.1 - 4.9 6.7 19.6 6.9 6.2 19.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Hydin_ADK PF17213.3 GAN02248.1 - 5.5 7.2 15.0 8 6.7 15.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Sec62 PF03839.16 GAN02248.1 - 5.8 6.3 24.0 11 5.4 24.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Raftlin PF15250.6 GAN02248.1 - 6.1 5.5 17.5 7.8 5.1 17.5 1.1 1 0 0 1 1 1 0 Raftlin ALMT PF11744.8 GAN02248.1 - 6.7 5.4 14.3 8 5.2 14.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Paramyxo_ncap PF00973.19 GAN02248.1 - 6.8 5.5 16.2 8.3 5.2 16.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF5427 PF10310.9 GAN02248.1 - 7.1 5.5 25.1 9.1 5.1 25.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Dsh_C PF12316.8 GAN02248.1 - 9.6 6.5 15.8 13 6.1 15.8 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Glyco_hydro_18 PF00704.28 GAN02249.1 - 2.3e-68 231.2 3.7 3e-68 230.9 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4238 PF14022.6 GAN02249.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) ABC1 PF03109.16 GAN02250.1 - 7.3e-28 97.1 0.1 1.5e-27 96.1 0.1 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 GAN02250.1 - 0.00042 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 GAN02250.1 - 0.00095 18.8 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 RIO1 family HEPN_Swt1 PF18731.1 GAN02250.1 - 0.025 14.9 1.0 0.1 13.0 0.0 2.5 3 0 0 3 3 3 0 Swt1-like HEPN Methyltransf_31 PF13847.6 GAN02251.1 - 2.3e-07 30.7 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN02251.1 - 8.2e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN02251.1 - 1.1e-06 29.2 0.0 1.9e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN02251.1 - 4.8e-05 24.0 0.0 8.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN02251.1 - 8.3e-05 23.2 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN02251.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase RVT_1 PF00078.27 GAN02252.1 - 3.8e-18 65.8 0.0 8e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_1 PF02899.17 GAN02252.1 - 0.009 16.3 0.7 0.16 12.3 0.1 3.1 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain RNase_H PF00075.24 GAN02252.1 - 0.025 14.8 0.0 0.025 14.8 0.0 2.2 2 0 0 2 2 2 0 RNase H eIF-3_zeta PF05091.12 GAN02252.1 - 0.062 12.3 8.8 0.099 11.6 8.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_Maf PF03131.17 GAN02252.1 - 0.38 11.3 21.6 0.074 13.6 15.7 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Roughex PF06020.11 GAN02252.1 - 0.38 9.8 8.0 0.71 8.9 8.0 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Miga PF10265.9 GAN02252.1 - 0.59 9.0 4.6 1 8.2 4.6 1.3 1 0 0 1 1 1 0 Mitoguardin DUF4407 PF14362.6 GAN02252.1 - 1 8.7 7.8 1.5 8.1 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Suf PF05843.14 GAN02252.1 - 1.3 9.0 12.2 2.7 7.9 12.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.6 GAN02252.1 - 5.8 4.7 24.0 11 3.8 24.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CPSase_L_D2 PF02786.17 GAN02253.1 - 3.2e-65 219.6 0.0 6.6e-65 218.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAN02253.1 - 9.2e-44 148.5 0.1 1.9e-43 147.5 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN02253.1 - 3.9e-38 129.9 0.0 3.1e-36 123.7 0.0 2.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain SGS PF05002.15 GAN02253.1 - 2.4e-32 110.9 0.7 5.5e-32 109.7 0.7 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.16 GAN02253.1 - 2.3e-15 57.4 0.5 7e-15 55.8 0.5 1.9 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 GAN02253.1 - 1.3e-09 37.5 5.2 0.00017 21.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Dala_Dala_lig_C PF07478.13 GAN02253.1 - 2.3e-07 30.6 0.0 8.9e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus TPR_19 PF14559.6 GAN02253.1 - 1.1e-06 29.0 0.6 0.036 14.6 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Biotin_lipoyl PF00364.22 GAN02253.1 - 6.1e-06 26.0 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme TPR_12 PF13424.6 GAN02253.1 - 7.7e-06 26.1 4.3 0.00012 22.3 2.6 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN02253.1 - 4.6e-05 23.9 0.6 0.25 12.3 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN02253.1 - 5.2e-05 22.9 3.3 0.00027 20.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ATP-grasp PF02222.22 GAN02253.1 - 6.7e-05 22.5 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain TPR_16 PF13432.6 GAN02253.1 - 8.3e-05 23.2 2.3 0.016 15.8 0.2 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat ATP-grasp_3 PF02655.14 GAN02253.1 - 0.00023 21.2 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 GAN02253.1 - 0.00071 19.7 0.2 0.0022 18.1 0.2 1.9 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 TPR_8 PF13181.6 GAN02253.1 - 0.0011 19.0 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN02253.1 - 0.0056 16.6 0.2 0.82 9.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAN02253.1 - 0.023 14.8 0.7 0.16 12.2 0.7 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAN02253.1 - 0.024 15.2 0.5 0.17 12.6 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ATPgrasp_ST PF14397.6 GAN02253.1 - 0.027 13.7 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp TPR_MalT PF17874.1 GAN02253.1 - 0.087 12.2 0.6 0.16 11.3 0.6 1.4 1 0 0 1 1 1 0 MalT-like TPR region TPR_10 PF13374.6 GAN02253.1 - 0.14 12.1 0.3 0.54 10.2 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN02253.1 - 0.15 12.3 1.4 0.69 10.2 1.0 2.2 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 UMP1 PF05348.11 GAN02254.1 - 3.9e-40 136.8 0.6 4.5e-40 136.5 0.6 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Amidohydro_2 PF04909.14 GAN02255.1 - 4.2e-31 108.8 0.2 5.4e-31 108.4 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_S8 PF00410.19 GAN02256.1 - 3e-24 85.4 0.0 3.4e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 MFS_1 PF07690.16 GAN02257.1 - 1.1e-43 149.6 29.5 1.1e-43 149.6 29.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN02257.1 - 7e-17 61.4 15.0 7e-17 61.4 15.0 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAN02257.1 - 2.9e-05 22.7 3.9 2.9e-05 22.7 3.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Saf_2TM PF18303.1 GAN02257.1 - 0.011 15.3 0.3 0.044 13.4 0.3 2.0 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Wzz PF02706.15 GAN02257.1 - 0.84 10.0 4.3 34 4.8 0.0 3.4 3 0 0 3 3 3 0 Chain length determinant protein PsbI PF02532.14 GAN02257.1 - 1.2 9.1 5.3 13 5.8 0.6 3.1 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Arrestin_C PF02752.22 GAN02258.1 - 9.4e-08 32.6 10.9 0.003 18.0 2.1 3.3 2 1 1 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN02258.1 - 6.4e-06 26.3 0.8 0.00024 21.2 0.0 3.3 3 1 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.16 GAN02259.1 - 2.6e-26 92.4 23.1 3.1e-26 92.1 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Tox-SGS PF15651.6 GAN02259.1 - 0.13 12.5 0.0 0.55 10.5 0.0 2.0 2 0 0 2 2 2 0 Salivary glad secreted protein domain toxin Sacchrp_dh_C PF16653.5 GAN02260.1 - 6.4e-93 311.7 0.0 2.1e-92 310.0 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 GAN02260.1 - 8.1e-26 90.8 0.2 1.6e-25 89.9 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAN02260.1 - 2e-08 34.4 0.1 3.6e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 GAN02260.1 - 0.0014 18.5 0.1 0.003 17.5 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 GAN02260.1 - 0.0039 16.8 0.7 0.018 14.6 0.1 2.2 3 1 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN02260.1 - 0.039 13.4 0.4 0.24 10.8 0.1 2.3 3 1 0 3 3 3 0 short chain dehydrogenase NAT PF04768.13 GAN02261.1 - 2e-39 135.0 0.4 5.3e-39 133.6 0.1 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 GAN02261.1 - 1.9e-30 106.2 0.1 5.8e-30 104.7 0.0 1.8 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 GAN02261.1 - 1.8e-29 102.6 0.0 4.6e-29 101.3 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 GAN02261.1 - 4.7e-11 43.1 0.0 1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 GAN02261.1 - 0.014 15.5 0.0 0.055 13.6 0.0 2.2 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 GAN02261.1 - 0.039 14.8 0.0 0.098 13.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold zf-DNL PF05180.12 GAN02263.1 - 1.7e-32 111.2 0.7 3.8e-32 110.0 0.7 1.6 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 GAN02263.1 - 0.033 14.2 0.3 0.077 13.1 0.3 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CcmH PF03918.14 GAN02263.1 - 0.088 12.1 0.2 0.69 9.2 0.0 2.2 1 1 1 2 2 2 0 Cytochrome C biogenesis protein IGPD PF00475.18 GAN02263.1 - 0.14 12.5 0.3 0.42 10.9 0.0 1.9 2 1 1 3 3 3 0 Imidazoleglycerol-phosphate dehydratase UPF0167 PF03691.14 GAN02263.1 - 0.19 11.5 3.2 0.6 9.9 3.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) NIR_SIR PF01077.22 GAN02264.1 - 5.8e-52 175.4 0.0 1.2e-48 164.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 GAN02264.1 - 6.3e-31 107.5 0.1 2.9e-30 105.4 0.1 2.2 2 0 0 2 2 2 1 Flavodoxin NIR_SIR_ferr PF03460.17 GAN02264.1 - 1.4e-26 92.1 0.1 4.2e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 GAN02264.1 - 2.3e-18 66.8 0.7 5.2e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 GAN02264.1 - 2.6e-07 30.9 0.0 1.6e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Flavodoxin_5 PF12724.7 GAN02264.1 - 0.0042 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Pilus_CpaD PF09476.10 GAN02264.1 - 0.011 15.5 1.3 0.064 13.0 0.1 2.6 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Flavodoxin_3 PF12641.7 GAN02264.1 - 0.042 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain PilP PF04351.13 GAN02264.1 - 0.097 12.6 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 Pilus assembly protein, PilP DUF573 PF04504.14 GAN02265.1 - 0.024 15.3 2.7 0.024 15.3 2.7 3.4 2 1 1 4 4 4 0 Protein of unknown function, DUF573 Complex1_51K PF01512.17 GAN02266.1 - 9.3e-49 165.2 0.0 1.4e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GAN02266.1 - 6.2e-31 106.3 0.1 1.2e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GAN02266.1 - 2.9e-07 30.2 0.0 5.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 GAN02266.1 - 0.13 12.4 0.3 0.23 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Glyco_hydro_17 PF00332.18 GAN02267.1 - 5.3e-21 75.5 0.3 4.2e-12 46.3 0.0 2.6 2 1 1 3 3 3 2 Glycosyl hydrolases family 17 ChAPs PF09295.10 GAN02268.1 - 5.9e-156 519.4 0.1 2.3e-152 507.6 0.0 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 GAN02268.1 - 0.018 15.5 0.6 3.7 8.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat LAP1C PF05609.12 GAN02268.1 - 0.9 8.6 20.2 1.3 8.0 20.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ndc1_Nup PF09531.10 GAN02268.1 - 0.98 8.0 8.1 1.4 7.5 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_8 PF13181.6 GAN02268.1 - 1 9.7 4.7 49 4.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN02268.1 - 1 9.6 9.7 1.5 9.1 0.4 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Sulfate_transp PF00916.20 GAN02269.1 - 3.3e-107 358.6 24.0 4.6e-107 358.1 24.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN02269.1 - 4.8e-08 32.6 0.0 9.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN02269.1 - 4.6e-06 27.0 6.0 4.6e-06 27.0 6.0 3.5 4 1 0 4 4 4 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 GAN02269.1 - 0.064 13.6 0.9 0.84 10.0 0.1 2.4 2 0 0 2 2 2 0 STAS domain Pkinase PF00069.25 GAN02270.1 - 8.3e-74 248.3 0.0 1.2e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02270.1 - 4.7e-31 108.0 0.0 1.5e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN02270.1 - 2.4e-08 33.6 0.1 0.14 11.5 0.1 3.2 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 GAN02270.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAN02270.1 - 0.027 13.2 0.0 0.069 11.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase DUF1771 PF08590.10 GAN02271.1 - 1.8e-20 73.0 13.1 4.1e-20 71.9 13.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 GAN02271.1 - 8.8e-11 42.0 0.7 1.9e-10 40.9 0.0 2.0 2 1 0 2 2 2 1 Smr domain Reo_P9 PF06043.11 GAN02271.1 - 0.059 12.8 2.1 0.084 12.3 2.1 1.2 1 0 0 1 1 1 0 Reovirus P9-like family DUF4407 PF14362.6 GAN02271.1 - 5.3 6.3 9.9 7.4 5.8 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XRN_M PF17846.1 GAN02271.1 - 7.7 5.3 12.6 15 4.3 11.4 1.8 1 1 1 2 2 2 0 Xrn1 helical domain ESM4 PF15952.5 GAN02271.1 - 9.8 6.6 16.3 21 5.5 16.3 1.6 1 1 0 1 1 1 0 Enhancer of split M4 family DUF5305 PF17231.2 GAN02272.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4366 PF14283.6 GAN02272.1 - 0.089 12.8 0.7 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) FmiP_Thoc5 PF09766.9 GAN02273.1 - 1.2e-27 97.2 14.3 1.8e-27 96.6 14.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 LMBR1 PF04791.16 GAN02273.1 - 1.6 7.6 4.6 1.8 7.4 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein KOG2701 PF09762.9 GAN02273.1 - 2.4 8.4 7.7 3.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) Macoilin PF09726.9 GAN02273.1 - 6.4 5.2 13.9 0.63 8.5 9.3 1.5 2 0 0 2 2 2 0 Macoilin family Atg14 PF10186.9 GAN02273.1 - 7.6 5.5 11.5 8.3 5.4 10.4 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 GAN02274.1 - 3e-43 145.0 18.2 5.3e-07 30.2 0.1 11.5 11 0 0 11 11 11 7 WD domain, G-beta repeat Utp12 PF04003.12 GAN02274.1 - 9.3e-26 90.2 0.0 1.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAN02274.1 - 8.6e-25 86.9 0.0 0.0051 17.1 0.0 10.0 3 2 8 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN02274.1 - 2.3e-09 36.7 2.9 0.022 13.7 0.0 6.7 4 2 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAN02274.1 - 2.4e-09 37.3 4.0 0.16 11.8 0.0 5.5 2 2 2 5 5 5 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAN02274.1 - 0.00021 20.8 0.1 0.2 11.0 0.0 3.3 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 GAN02274.1 - 0.00097 18.5 0.1 3.3 7.0 0.0 4.1 4 1 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 GAN02274.1 - 0.002 18.0 7.3 0.024 14.6 0.1 5.6 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 GAN02274.1 - 0.011 14.9 0.0 12 4.8 0.0 3.8 3 1 0 3 3 3 0 Coatomer WD associated region RAB3GAP2_N PF14655.6 GAN02274.1 - 0.018 14.3 0.1 0.14 11.4 0.0 2.3 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 GAN02274.1 - 0.047 12.2 0.3 13 4.2 0.0 3.5 4 1 0 4 4 4 0 Cytochrome D1 heme domain DUF4061 PF13270.6 GAN02275.1 - 6.1e-05 23.3 0.2 0.00019 21.7 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4061) zf-C4H2 PF10146.9 GAN02275.1 - 0.39 11.0 3.5 0.24 11.7 1.7 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein DHDPS PF00701.22 GAN02276.1 - 5.4e-51 173.0 0.0 6.4e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PucR PF07905.11 GAN02276.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family ABC_membrane_2 PF06472.15 GAN02279.1 - 1.4e-51 175.5 2.2 1.4e-51 175.5 2.2 2.4 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAN02279.1 - 8.3e-19 68.5 0.0 1.5e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAN02279.1 - 4.7e-06 26.6 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN02279.1 - 4.2e-05 23.1 0.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAN02279.1 - 0.00072 20.1 1.5 0.0016 19.0 0.1 2.3 2 1 1 3 3 3 1 AAA domain AAA_15 PF13175.6 GAN02279.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAN02279.1 - 0.0089 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GAN02279.1 - 0.041 13.6 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAN02279.1 - 0.17 12.3 0.0 0.49 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 GAN02281.1 - 1.6e-44 151.8 0.1 9.5e-44 149.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase VASt PF16016.5 GAN02281.1 - 1.1e-32 113.6 0.8 2.6e-32 112.4 0.8 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Helicase_C PF00271.31 GAN02281.1 - 2.4e-30 105.1 0.0 1e-29 103.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BAR_3 PF16746.5 GAN02281.1 - 1e-25 90.9 4.5 1e-25 90.9 4.5 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 GAN02281.1 - 4.2e-12 46.5 1.6 3.1e-11 43.7 0.1 2.9 2 0 0 2 2 2 1 PH domain BAR PF03114.18 GAN02281.1 - 0.00065 19.4 0.4 0.00065 19.4 0.4 2.2 2 0 0 2 2 2 1 BAR domain ThrE PF06738.12 GAN02282.1 - 3.1e-37 128.2 27.4 1.4e-34 119.5 7.6 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAN02282.1 - 1.4e-05 25.3 11.1 1.4e-05 25.3 11.1 3.0 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE DUF4225 PF13988.6 GAN02282.1 - 0.022 14.3 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) MHYT PF03707.16 GAN02282.1 - 1.8 8.8 10.0 0.57 10.4 0.3 4.0 3 1 1 4 4 4 0 Bacterial signalling protein N terminal repeat Cyclin PF08613.11 GAN02283.1 - 2e-40 138.8 1.9 2.8e-40 138.3 1.9 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN02283.1 - 0.00075 19.2 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Med3 PF11593.8 GAN02284.1 - 0.03 13.5 6.0 0.048 12.9 6.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PGK PF00162.19 GAN02285.1 - 2.6e-14 53.0 0.0 3.4e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase La PF05383.17 GAN02285.1 - 0.047 13.7 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 La domain PGK PF00162.19 GAN02286.1 - 0.0076 15.2 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglycerate kinase Elongin_A PF06881.11 GAN02286.1 - 0.096 13.2 0.0 0.096 13.2 0.0 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Methyltransf_25 PF13649.6 GAN02287.1 - 0.00092 19.9 0.0 0.0026 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 GAN02287.1 - 0.01 15.0 0.2 0.014 14.5 0.2 1.4 1 1 0 1 1 1 0 mRNA capping enzyme Methyltransf_31 PF13847.6 GAN02287.1 - 0.047 13.5 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 GAN02287.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Homeodomain PF00046.29 GAN02288.1 - 4.7e-15 55.2 6.1 7.7e-15 54.5 6.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN02288.1 - 0.0014 18.5 1.2 0.0028 17.5 1.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Formyl_trans_N PF00551.19 GAN02288.1 - 0.041 13.6 0.4 0.11 12.3 0.4 1.7 1 0 0 1 1 1 0 Formyl transferase Optomotor-blind PF11078.8 GAN02288.1 - 0.051 14.1 4.1 0.14 12.7 4.1 1.8 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region IGPS PF00218.21 GAN02289.1 - 2.3e-91 305.5 1.5 6.9e-91 303.9 0.1 2.3 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 GAN02289.1 - 2.2e-50 171.1 0.2 1.4e-42 145.7 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 GAN02289.1 - 8.8e-49 165.9 0.0 1.5e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAN02289.1 - 1.2e-09 38.3 0.8 4.2e-09 36.5 0.1 2.3 2 1 0 2 2 2 1 Peptidase C26 NanE PF04131.14 GAN02289.1 - 0.0054 16.0 0.2 2.7 7.1 0.0 3.4 3 0 0 3 3 3 2 Putative N-acetylmannosamine-6-phosphate epimerase Glutaredoxin PF00462.24 GAN02290.1 - 8.9e-17 61.1 0.0 1.6e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin HMG_box PF00505.19 GAN02291.1 - 8.4e-18 64.6 0.3 1.3e-17 63.9 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN02291.1 - 1.7e-12 47.8 0.2 2.7e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 HMG-box domain DUF3083 PF11281.8 GAN02291.1 - 0.2 10.9 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Ribosomal_S3Ae PF01015.18 GAN02292.1 - 5.5e-84 280.8 4.9 6.8e-84 280.5 4.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF5025 PF16428.5 GAN02292.1 - 0.092 12.9 0.3 0.18 12.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5025) EF-hand_7 PF13499.6 GAN02293.1 - 7.9e-12 45.5 1.8 1e-11 45.1 1.8 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAN02293.1 - 1.1e-10 40.6 2.5 3.3e-07 29.7 0.4 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 GAN02293.1 - 6.2e-10 37.9 1.6 0.00018 20.8 0.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAN02293.1 - 1.4e-08 33.8 1.4 0.0018 17.7 0.1 2.5 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAN02293.1 - 8.3e-05 22.4 1.4 0.00019 21.2 1.0 1.8 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAN02293.1 - 0.025 14.9 0.1 0.99 9.8 0.1 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAN02293.1 - 0.028 14.6 0.1 9 6.6 0.0 2.2 2 0 0 2 2 2 0 Dockerin type I domain FG-GAP PF01839.23 GAN02293.1 - 9.7 6.4 10.7 1 9.5 1.0 2.3 2 0 0 2 2 2 0 FG-GAP repeat ELO PF01151.18 GAN02294.1 - 7.4e-47 160.0 23.0 9.7e-47 159.6 23.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Metallophos PF00149.28 GAN02295.1 - 3e-07 31.2 4.2 3e-07 31.2 4.2 2.7 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAN02295.1 - 5.9e-07 29.8 2.0 6e-06 26.5 2.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PC-Esterase PF13839.6 GAN02295.1 - 0.00052 19.9 1.0 0.0052 16.6 0.0 2.8 3 1 0 3 3 3 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF4271 PF14093.6 GAN02295.1 - 0.0021 18.0 1.3 0.0034 17.3 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DUF2208 PF09973.9 GAN02295.1 - 0.061 12.9 1.1 0.098 12.3 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Ilm1 PF10311.9 GAN02295.1 - 0.077 12.6 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 RGS PF00615.19 GAN02296.1 - 2.7e-08 34.1 0.0 1.3e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 GAN02297.1 - 2.9e-72 243.2 0.0 3.9e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02297.1 - 5.9e-35 120.8 0.0 8.4e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN02297.1 - 8.8e-05 22.0 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF2252 PF10009.9 GAN02297.1 - 0.018 14.1 0.8 0.025 13.7 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) EI24 PF07264.11 GAN02298.1 - 1.7e-20 74.0 11.7 2.4e-20 73.5 11.7 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) MFS_1 PF07690.16 GAN02298.1 - 0.0021 17.0 5.9 0.0037 16.2 5.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily RhoGEF PF00621.20 GAN02300.1 - 1.2e-29 103.9 1.4 3.9e-29 102.2 0.3 2.3 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 GAN02300.1 - 3.3e-21 75.8 0.5 3.3e-21 75.8 0.5 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 GAN02300.1 - 1.1e-05 25.4 0.1 3.5e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2482 PF10655.9 GAN02300.1 - 0.11 13.0 0.2 0.95 10.0 0.0 2.6 3 0 0 3 3 3 0 Hypothetical protein of unknown function (DUF2482) RhoGAP PF00620.27 GAN02301.1 - 2.1e-30 105.6 0.7 3.4e-30 104.9 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FMO-like PF00743.19 GAN02302.1 - 1.5e-19 69.8 0.6 2.1e-18 66.1 0.6 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAN02302.1 - 1.4e-08 34.3 0.1 5.6e-07 29.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN02302.1 - 1.9e-08 34.4 0.0 1e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAN02302.1 - 1.9e-06 27.4 0.2 0.011 15.0 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAN02302.1 - 2.7e-05 23.6 0.2 0.22 10.7 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN02302.1 - 0.00015 21.5 0.0 0.0057 16.3 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAN02302.1 - 0.00085 19.3 0.0 0.19 11.7 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAN02302.1 - 0.0021 17.4 0.1 0.93 8.7 0.0 2.8 3 0 0 3 3 3 2 Thi4 family zf-C2H2 PF00096.26 GAN02303.1 - 1.2e-10 41.3 10.5 1.4e-05 25.3 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN02303.1 - 2e-09 37.4 21.8 4.3e-06 26.9 5.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN02303.1 - 6.3e-06 26.6 11.9 0.014 16.2 1.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 GAN02303.1 - 0.012 16.2 0.5 0.041 14.5 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain TPK_B1_binding PF04265.14 GAN02305.1 - 6.6e-19 67.4 0.0 1.1e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.16 GAN02305.1 - 1.5e-18 67.0 0.2 3.1e-11 43.4 0.1 2.8 1 1 2 3 3 3 2 Thiamin pyrophosphokinase, catalytic domain Cpn10 PF00166.21 GAN02306.1 - 1.3e-28 98.9 0.1 1.5e-28 98.7 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit zf-C2H2_2 PF12756.7 GAN02307.1 - 5.6e-32 110.1 13.6 3e-22 78.9 4.8 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAN02307.1 - 3.1e-05 24.2 12.3 0.00042 20.6 0.7 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN02307.1 - 6.2e-05 23.2 1.4 6.2e-05 23.2 1.4 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAN02307.1 - 0.0001 22.9 18.5 0.0041 17.8 0.5 5.5 5 0 0 5 5 5 1 C2H2-type zinc finger SPX PF03105.19 GAN02307.1 - 0.0006 19.8 5.4 0.0012 18.9 5.4 1.4 1 1 0 1 1 1 1 SPX domain zf-C2H2 PF00096.26 GAN02307.1 - 0.00066 20.0 1.4 0.00066 20.0 1.4 5.4 6 0 0 6 6 5 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GAN02307.1 - 0.0023 17.6 0.4 0.0023 17.6 0.4 3.0 3 1 0 3 3 3 1 zinc-finger C2H2-type zf-BED PF02892.15 GAN02307.1 - 0.031 14.3 0.3 0.031 14.3 0.3 3.8 5 0 0 5 5 5 0 BED zinc finger PyrI_C PF02748.15 GAN02307.1 - 0.14 12.1 2.1 0.2 11.6 0.0 2.4 3 0 0 3 3 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Clr5 PF14420.6 GAN02307.1 - 0.16 12.2 3.2 13 6.1 0.0 3.3 3 0 0 3 3 3 0 Clr5 domain CENP-B_dimeris PF09026.10 GAN02307.1 - 0.31 11.5 16.0 0.17 12.3 0.5 3.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Spem1 PF15670.5 GAN02307.1 - 0.32 10.5 8.7 0.86 9.1 6.0 2.5 2 0 0 2 2 2 0 Spermatid maturation protein 1 FOXP-CC PF16159.5 GAN02307.1 - 0.46 11.2 9.6 15 6.3 0.0 5.2 5 0 0 5 5 5 0 FOXP coiled-coil domain DUF1548 PF07579.11 GAN02307.1 - 0.55 10.6 3.2 5.4 7.4 0.8 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1548) Syntaxin_2 PF14523.6 GAN02308.1 - 4.3e-27 94.4 4.0 4.3e-27 94.4 4.0 2.7 2 1 0 3 3 3 1 Syntaxin-like protein Syntaxin PF00804.25 GAN02308.1 - 3.9e-08 33.2 16.4 8.9e-08 32.0 16.1 1.8 1 1 0 1 1 1 1 Syntaxin CEP209_CC5 PF16574.5 GAN02308.1 - 0.02 15.0 3.9 0.02 15.0 3.9 2.3 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF4487 PF14868.6 GAN02308.1 - 0.069 12.0 2.0 0.088 11.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) FUSC PF04632.12 GAN02308.1 - 0.13 10.8 2.0 0.14 10.6 2.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.6 GAN02308.1 - 0.2 11.8 13.2 12 6.0 11.6 2.4 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4162 PF13732.6 GAN02308.1 - 0.53 11.0 3.7 0.58 10.9 1.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) LysM PF01476.20 GAN02309.1 - 0.0059 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain DAO PF01266.24 GAN02310.1 - 1.4e-41 143.3 0.0 1.6e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN02310.1 - 3.6e-07 30.3 0.1 2.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN02310.1 - 5e-07 29.2 0.0 0.15 11.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN02310.1 - 2.2e-06 27.7 0.1 0.00028 20.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 GAN02310.1 - 0.00027 20.1 0.1 0.017 14.2 0.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAN02310.1 - 0.004 16.5 0.0 0.84 8.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAN02310.1 - 0.0078 15.5 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GAN02310.1 - 0.038 12.7 0.0 6 5.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_6 PF01341.17 GAN02310.1 - 0.047 13.4 0.5 0.074 12.8 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 Pyr_redox PF00070.27 GAN02310.1 - 0.077 13.6 0.2 1.3 9.6 0.0 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAN02310.1 - 0.1 11.6 0.6 2.2 7.2 0.6 2.2 1 1 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 GAN02310.1 - 0.12 11.5 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NTP_transf_2 PF01909.23 GAN02312.1 - 1.4e-12 47.7 0.0 4.9e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 GAN02312.1 - 4e-10 39.8 0.0 1.1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 GAN02312.1 - 0.00089 19.3 0.0 0.0029 17.7 0.0 1.9 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase MFS_1 PF07690.16 GAN02313.1 - 5.1e-31 107.9 33.2 1.6e-29 102.9 30.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.24 GAN02313.1 - 4.7 7.0 7.5 1 9.2 1.4 2.6 2 0 0 2 2 2 0 Fatty acid desaturase FtsJ PF01728.19 GAN02314.1 - 8.8e-60 201.8 0.0 1.3e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 GAN02314.1 - 5.1e-05 23.1 0.0 0.056 13.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltr_RsmB-F PF01189.17 GAN02314.1 - 0.009 15.7 0.0 0.021 14.5 0.0 1.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 GAN02314.1 - 0.02 15.6 0.1 0.078 13.7 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAN02314.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain NTF2 PF02136.20 GAN02315.1 - 5.7e-23 81.8 0.1 6.5e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 GAN02315.1 - 9.6e-08 32.1 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Dna2 PF08696.11 GAN02316.1 - 1.8e-57 194.4 0.7 3.8e-57 193.4 0.7 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 GAN02316.1 - 5.5e-52 176.3 1.0 1e-51 175.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain Rap_GAP PF02145.15 GAN02316.1 - 2.8e-51 173.7 1.0 1.9e-50 171.0 0.1 2.9 2 1 0 2 2 2 1 Rap/ran-GAP AAA_11 PF13086.6 GAN02316.1 - 5.6e-31 108.3 4.5 3.1e-16 59.9 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 GAN02316.1 - 4.1e-14 52.7 0.0 2e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAN02316.1 - 1.1e-10 42.0 0.0 2.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 GAN02316.1 - 1.8e-05 24.9 0.1 0.00016 21.9 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 GAN02316.1 - 2.4e-05 24.2 0.0 7.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Helicase SRP54 PF00448.22 GAN02316.1 - 0.00043 20.0 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.15 GAN02316.1 - 0.0034 17.4 0.2 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAN02316.1 - 0.0047 16.5 0.0 0.024 14.2 0.0 2.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GAN02316.1 - 0.0078 16.6 0.1 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 GAN02316.1 - 0.014 14.5 0.0 0.033 13.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 GAN02316.1 - 0.014 14.5 0.0 0.17 11.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ATPase PF06745.13 GAN02316.1 - 0.021 14.2 0.0 0.081 12.3 0.0 2.0 1 0 0 1 1 1 0 KaiC DUF87 PF01935.17 GAN02316.1 - 0.025 14.7 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain UvrD_C_2 PF13538.6 GAN02316.1 - 0.026 14.3 0.0 0.086 12.7 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 GAN02316.1 - 0.077 13.4 0.2 0.55 10.7 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Csa1 PF06023.12 GAN02316.1 - 0.098 12.0 0.3 0.26 10.6 0.3 1.7 1 1 0 1 1 1 0 CRISPR-associated exonuclease Csa1 CbiA PF01656.23 GAN02316.1 - 0.11 12.5 0.0 0.5 10.4 0.0 2.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.20 GAN02317.1 - 5.4e-118 394.2 2.5 7.5e-118 393.7 2.5 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN02317.1 - 6.1e-16 58.4 0.6 4.6e-10 39.2 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN02317.1 - 0.00012 21.5 2.6 0.0078 15.6 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAN02317.1 - 0.0036 17.5 0.6 2.1 8.6 0.0 3.0 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 GAN02317.1 - 0.0096 15.7 0.0 0.099 12.5 0.0 2.4 2 0 0 2 2 2 1 CHC2 zinc finger MCM PF00493.23 GAN02317.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 GAN02317.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GAN02317.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ank_2 PF12796.7 GAN02318.1 - 1.4e-26 92.9 7.8 5e-09 36.6 0.3 5.2 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN02318.1 - 3.8e-19 68.8 11.4 3.1e-05 24.4 0.0 7.8 5 2 1 6 6 6 5 Ankyrin repeats (many copies) VPS9 PF02204.18 GAN02318.1 - 2.4e-16 59.8 0.4 9.3e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank PF00023.30 GAN02318.1 - 1.4e-15 57.0 8.1 0.00099 19.5 0.6 7.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 GAN02318.1 - 1.8e-14 52.4 8.2 0.61 10.8 0.1 8.8 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 GAN02318.1 - 1.4e-10 41.2 12.6 0.032 14.5 0.0 6.3 4 2 1 5 5 5 4 Ankyrin repeats (many copies) PX PF00787.24 GAN02318.1 - 0.01 15.8 0.1 0.03 14.3 0.1 1.8 1 0 0 1 1 1 0 PX domain Cluap1 PF10234.9 GAN02318.1 - 0.14 11.5 3.1 0.29 10.5 0.8 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 Pkinase PF00069.25 GAN02319.1 - 6.4e-69 232.2 0.0 9e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02319.1 - 9.5e-39 133.2 0.0 1.4e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN02319.1 - 5.4e-08 32.5 0.0 9.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN02319.1 - 0.00031 19.6 0.1 0.00067 18.5 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAN02319.1 - 0.00084 18.4 0.6 0.0016 17.4 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN02319.1 - 0.0011 18.4 0.4 0.0019 17.6 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN02319.1 - 0.023 14.6 0.8 0.034 14.0 0.8 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAN02319.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 GAN02320.1 - 3.6e-43 144.7 15.6 5.3e-07 30.2 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02320.1 - 2.4e-23 82.2 2.1 0.0007 19.8 0.0 7.0 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN02320.1 - 4.4e-07 30.0 0.9 0.56 10.0 0.0 3.8 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 GAN02320.1 - 4.3e-06 26.5 0.1 8.1e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 GAN02320.1 - 5.3e-05 22.7 0.0 0.008 15.5 0.0 3.4 3 1 0 3 3 3 1 WD40-like domain Draxin PF15550.6 GAN02320.1 - 0.046 13.6 7.8 0.071 13.0 7.8 1.2 1 0 0 1 1 1 0 Draxin SOBP PF15279.6 GAN02320.1 - 0.47 11.0 5.6 0.69 10.5 5.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Dicty_REP PF05086.12 GAN02320.1 - 1.7 6.6 9.5 2.3 6.1 9.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Atg14 PF10186.9 GAN02321.1 - 2.9e-23 82.4 7.3 2.9e-23 82.4 7.3 2.6 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 PBP1_TM PF14812.6 GAN02321.1 - 0.2 12.1 3.8 0.51 10.8 3.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TBCA PF02970.16 GAN02321.1 - 9.4 6.6 10.2 1.6 9.1 2.5 2.6 2 0 0 2 2 2 0 Tubulin binding cofactor A Sel1 PF08238.12 GAN02322.1 - 9.7e-41 137.3 38.5 2.6e-07 31.1 0.5 7.7 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 GAN02322.1 - 0.68 10.7 13.7 0.87 10.4 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAN02322.1 - 7.3 7.2 9.6 18 5.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat FYRN PF05964.14 GAN02323.1 - 9.8e-18 63.7 1.3 2.3e-17 62.5 1.3 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 GAN02323.1 - 4.2e-13 49.3 0.0 1.2e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus Glycos_transf_1 PF00534.20 GAN02324.1 - 1.6e-31 109.1 0.0 3.1e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN02324.1 - 8.7e-27 94.2 0.0 2.3e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN02324.1 - 7.4e-24 84.6 0.1 2.9e-23 82.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAN02324.1 - 1.9e-10 41.4 0.0 3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAN02324.1 - 0.00067 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_S31 PF05578.12 GAN02324.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 Reprolysin_5 PF13688.6 GAN02325.1 - 1.2e-37 129.9 6.0 1.2e-37 129.9 6.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 GAN02325.1 - 2.8e-35 122.0 2.2 2.8e-35 122.0 2.2 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAN02325.1 - 1.2e-32 113.2 1.3 2.5e-32 112.2 1.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 GAN02325.1 - 3.1e-15 56.7 23.5 3.1e-15 56.7 23.5 4.1 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 GAN02325.1 - 2.3e-13 50.8 0.1 5.5e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 GAN02325.1 - 9.8e-06 25.8 0.0 3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.19 GAN02325.1 - 2.9e-05 24.1 11.3 0.00012 22.0 11.3 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease MLANA PF14991.6 GAN02325.1 - 0.033 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A RCR PF12273.8 GAN02325.1 - 0.14 12.8 0.1 0.56 10.9 0.1 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Biopterin_H PF00351.21 GAN02326.1 - 1.3e-166 553.6 0.0 1.6e-166 553.3 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 GAN02326.1 - 0.0086 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain CDC50 PF03381.15 GAN02327.1 - 1.4e-83 280.7 0.2 1.6e-83 280.4 0.2 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family WH1 PF00568.23 GAN02328.1 - 4.4e-23 81.3 0.1 6.4e-23 80.8 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 GAN02328.1 - 1.2e-07 31.9 0.1 3.1e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 GAN02328.1 - 0.00077 19.2 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 WH2 motif Ribonucleas_3_3 PF14622.6 GAN02330.1 - 1.6e-23 83.3 0.0 2.5e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAN02330.1 - 4.6e-12 46.5 0.0 1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 GAN02330.1 - 1.7e-07 31.8 0.0 3.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif KAP_NTPase PF07693.14 GAN02330.1 - 0.097 11.9 0.1 5.9 6.0 0.0 2.1 1 1 0 2 2 2 0 KAP family P-loop domain MIR PF02815.19 GAN02331.1 - 2.1e-13 50.5 0.0 1.8e-12 47.5 0.0 1.9 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 GAN02331.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor TMEM70 PF06979.12 GAN02332.1 - 0.04 14.3 0.1 0.075 13.4 0.1 1.5 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex NADHdh-2_N PF12155.8 GAN02332.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal RGS PF00615.19 GAN02333.1 - 6.7e-11 42.5 4.3 2.4e-10 40.7 4.3 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 GAN02333.1 - 0.038 13.7 1.0 0.12 12.1 0.4 1.9 1 1 1 2 2 2 0 Regulator of G protein signalling-like domain PH PF00169.29 GAN02334.1 - 4.1e-07 30.5 12.1 0.00024 21.5 0.1 5.3 2 2 1 4 4 4 2 PH domain PH_15 PF17339.2 GAN02334.1 - 0.012 15.5 0.1 0.21 11.5 0.1 2.7 2 0 0 2 2 2 0 PH domain DdrB PF12747.7 GAN02334.1 - 0.03 14.1 0.0 0.095 12.5 0.0 1.9 1 0 0 1 1 1 0 DdrB-like protein PH_13 PF16652.5 GAN02334.1 - 0.034 14.0 0.2 0.67 9.7 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain PH_9 PF15410.6 GAN02334.1 - 4.7 7.6 8.7 11 6.4 0.1 4.1 5 0 0 5 5 5 0 Pleckstrin homology domain CSD PF00313.22 GAN02335.1 - 3.9e-14 52.3 0.0 1.4e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain BLOC1_2 PF10046.9 GAN02336.1 - 0.00021 21.5 3.4 0.0004 20.6 3.0 1.6 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DHR10 PF18595.1 GAN02336.1 - 0.0035 17.4 3.2 0.004 17.2 3.2 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DUF4200 PF13863.6 GAN02336.1 - 0.0049 17.3 3.5 0.0064 16.9 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Sec34 PF04136.15 GAN02336.1 - 0.0055 16.6 2.7 0.0066 16.3 2.7 1.2 1 0 0 1 1 1 1 Sec34-like family DUF948 PF06103.11 GAN02336.1 - 0.0076 16.5 3.4 0.014 15.6 3.4 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) MIT PF04212.18 GAN02336.1 - 0.0096 16.0 0.1 0.13 12.4 0.0 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Fib_alpha PF08702.10 GAN02336.1 - 0.02 15.1 2.7 0.022 14.9 2.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Arm-DNA-bind_5 PF17293.2 GAN02336.1 - 0.024 15.1 0.6 0.028 14.8 0.6 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain DUF3450 PF11932.8 GAN02336.1 - 0.033 13.5 3.0 0.036 13.4 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sigma54_CBD PF04963.13 GAN02336.1 - 0.038 13.8 1.0 0.046 13.6 1.0 1.4 1 1 0 1 1 1 0 Sigma-54 factor, core binding domain SesA PF17107.5 GAN02336.1 - 0.053 13.7 3.2 0.23 11.6 3.2 1.8 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2748 PF10871.8 GAN02336.1 - 0.058 12.0 1.4 0.064 11.9 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) ATG11 PF10377.9 GAN02336.1 - 0.074 13.1 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 MCPsignal PF00015.21 GAN02336.1 - 0.086 12.7 2.5 0.096 12.5 2.5 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C2H2 PF00096.26 GAN02337.1 - 1.1e-06 28.8 28.0 1.4e-05 25.2 0.4 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN02337.1 - 6.4e-06 26.4 20.2 2.8e-05 24.4 1.4 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf_Hakai PF18408.1 GAN02337.1 - 5.3e-05 22.8 1.6 0.013 15.2 0.4 3.0 2 0 0 2 2 2 2 C2H2 Hakai zinc finger domain zf-C2H2_4 PF13894.6 GAN02337.1 - 0.00072 20.2 22.0 0.00083 20.0 0.3 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAN02337.1 - 0.024 14.9 11.9 1.1 9.6 6.3 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAN02337.1 - 0.027 15.1 0.1 0.027 15.1 0.1 6.2 5 2 2 7 7 7 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 GAN02337.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN02337.1 - 0.34 11.3 0.2 0.34 11.3 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 GAN02338.1 - 1.6e-07 31.0 0.0 3.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 GAN02338.1 - 0.58 10.3 7.5 0.32 11.1 0.2 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ATP-synt PF00231.19 GAN02339.1 - 6.4e-75 252.4 6.6 7.3e-75 252.3 6.6 1.0 1 0 0 1 1 1 1 ATP synthase AHD PF17793.1 GAN02339.1 - 1.1 9.1 3.2 1.2 9.0 1.1 2.1 2 0 0 2 2 2 0 ANC1 homology domain (AHD) GCOM2 PF15328.6 GAN02340.1 - 0.0025 18.2 8.7 0.026 14.9 8.7 2.5 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 DUF155 PF02582.14 GAN02341.1 - 4.4e-56 189.7 0.9 8.6e-56 188.8 0.5 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 LTXXQ PF07813.12 GAN02341.1 - 0.2 12.4 5.0 0.31 11.8 2.0 2.3 1 1 1 2 2 2 0 LTXXQ motif family protein Pox_Ag35 PF03286.14 GAN02341.1 - 0.28 10.9 5.4 0.1 12.4 2.1 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRM_1 PF00076.22 GAN02342.1 - 1.4e-09 37.6 0.1 5.6e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN02342.1 - 3.6e-06 27.0 0.1 0.0052 16.8 0.0 3.7 3 1 0 3 3 3 2 RNA binding motif La PF05383.17 GAN02342.1 - 5.5e-06 26.3 0.2 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 La domain Prenyltrans PF00432.21 GAN02343.1 - 6.6e-65 214.5 1.8 5.8e-16 57.9 0.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAN02343.1 - 8.5e-07 28.4 0.2 8.8e-05 21.7 0.0 2.7 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAN02343.1 - 2e-06 27.1 0.0 0.16 11.0 0.0 3.5 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 GAN02343.1 - 0.0018 17.4 0.2 0.21 10.6 0.0 3.1 2 1 1 4 4 4 1 A-macroglobulin TED domain F-box-like PF12937.7 GAN02344.1 - 2.8e-12 46.3 1.6 3e-11 43.0 0.5 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN02344.1 - 6.4e-07 29.1 0.9 8.9e-05 22.3 0.1 2.6 2 0 0 2 2 2 2 F-box domain F-box_5 PF18511.1 GAN02344.1 - 0.0078 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 F-box F-box_4 PF15966.5 GAN02344.1 - 0.75 9.7 0.0 0.75 9.7 0.0 2.6 3 0 0 3 3 3 0 F-box MFS_1 PF07690.16 GAN02345.1 - 3.6e-24 85.4 47.7 6.2e-24 84.6 47.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN02345.1 - 9.1e-08 31.4 5.1 9.1e-08 31.4 5.1 3.7 1 1 1 4 4 4 2 Sugar (and other) transporter FGGY_C PF02782.16 GAN02346.1 - 1.8e-45 155.1 0.0 2.6e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAN02346.1 - 2.5e-26 92.8 0.8 1.8e-25 89.9 0.8 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 GAN02346.1 - 0.0021 17.6 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family zf-C2H2 PF00096.26 GAN02347.1 - 6.5e-07 29.5 9.8 0.0032 17.8 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAN02347.1 - 0.0019 18.8 1.0 1.5 9.5 0.1 2.8 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 GAN02347.1 - 0.002 18.4 3.7 0.26 11.6 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 GAN02347.1 - 0.0088 16.4 0.9 0.0088 16.4 0.9 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN02347.1 - 0.012 16.4 7.6 1.1 10.2 0.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 GAN02347.1 - 0.096 13.1 4.6 4.5 7.8 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAN02347.1 - 0.75 9.9 5.5 1 9.5 0.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 GAN02347.1 - 8.4 6.1 7.7 0.35 10.5 1.4 1.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Mito_carr PF00153.27 GAN02348.1 - 2.4e-29 101.1 8.5 1.1e-14 54.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ATG101 PF07855.12 GAN02349.1 - 1.4e-41 142.1 2.2 2.1e-41 141.5 2.2 1.2 1 0 0 1 1 1 1 Autophagy-related protein 101 Mur_ligase_M PF08245.12 GAN02350.1 - 5.5e-07 29.8 5.5 0.0011 19.0 1.1 3.6 2 1 1 3 3 3 2 Mur ligase middle domain Pyr_redox_3 PF13738.6 GAN02350.1 - 0.00012 21.4 0.4 0.0041 16.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mur_ligase_C PF02875.21 GAN02350.1 - 0.00017 21.8 0.1 0.00075 19.7 0.0 2.1 1 1 1 2 2 2 1 Mur ligase family, glutamate ligase domain MoCF_biosynth PF00994.24 GAN02351.1 - 1.1e-24 86.8 0.0 1.8e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Arrestin_N PF00339.29 GAN02352.1 - 1.1e-07 32.0 0.4 0.00014 21.9 0.0 3.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN02352.1 - 5.4e-06 26.9 0.7 2.2e-05 25.0 0.2 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Meth_synt_2 PF01717.18 GAN02353.1 - 1.7e-155 517.2 0.0 3.6e-145 483.3 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAN02353.1 - 2.8e-113 378.6 0.0 7.3e-107 357.5 0.1 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Ribosomal_L29 PF00831.23 GAN02354.1 - 5.5e-14 51.9 2.0 5.5e-14 51.9 2.0 2.1 1 1 1 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.19 GAN02354.1 - 0.044 14.3 3.1 0.073 13.6 3.1 1.5 1 1 1 2 2 2 0 Ribosomal protein S9/S16 CENP-B_N PF04218.13 GAN02354.1 - 0.25 11.0 4.8 6 6.6 0.1 3.1 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain KilA-N PF04383.13 GAN02355.1 - 0.0017 18.2 0.0 0.0072 16.2 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain MIT PF04212.18 GAN02356.1 - 6.5e-10 38.9 0.9 1.5e-09 37.7 0.5 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain CAP_GLY PF01302.25 GAN02358.1 - 6.3e-22 77.4 0.5 1e-21 76.7 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 GAN02358.1 - 1.2e-05 25.0 27.8 9.2e-05 22.2 7.2 2.7 3 0 0 3 3 3 2 CLIP1 zinc knuckle DUF3584 PF12128.8 GAN02358.1 - 0.97 6.9 74.5 0.2 9.2 38.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Metallophos PF00149.28 GAN02359.1 - 1.9e-37 129.7 0.4 2.9e-37 129.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN02359.1 - 1.4e-14 54.2 0.1 3.6e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ras PF00071.22 GAN02361.1 - 1.2e-33 116.0 0.0 1.4e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN02361.1 - 1.3e-16 60.9 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN02361.1 - 3.1e-07 30.0 0.0 3.4e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAN02361.1 - 0.0062 16.0 0.0 0.0071 15.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAN02361.1 - 0.022 14.1 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 GAN02361.1 - 0.039 13.7 0.2 0.14 11.9 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 GAN02361.1 - 0.051 13.7 0.0 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase CBS PF00571.28 GAN02363.1 - 7.5e-33 112.8 5.3 9.4e-09 35.6 0.0 5.4 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 GAN02363.1 - 7.6e-09 35.4 2.0 1.2e-07 31.5 2.0 2.6 1 1 0 1 1 1 1 PB1 domain E2F_TDP PF02319.20 GAN02364.1 - 7.4e-22 77.2 0.4 2.1e-21 75.7 0.4 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 GAN02364.1 - 4.8e-08 33.0 4.4 4.8e-08 33.0 4.4 2.1 3 0 0 3 3 3 1 Transcription factor DP YvrJ PF12841.7 GAN02365.1 - 0.23 11.0 4.9 2.1 7.9 0.3 2.5 2 0 0 2 2 2 0 YvrJ protein family UDPGP PF01704.18 GAN02366.1 - 4.9e-197 654.6 0.4 5.7e-197 654.3 0.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase rRNA_processing PF08524.11 GAN02367.1 - 7.1e-15 55.3 48.9 4e-12 46.4 35.6 2.1 1 1 0 2 2 2 2 rRNA processing FidL_like PF15941.5 GAN02367.1 - 2.8 8.4 5.4 1.3 9.5 0.5 2.3 2 0 0 2 2 2 0 FidL-like putative membrane protein ABA_GPCR PF12430.8 GAN02368.1 - 4.7e-36 124.2 11.9 4.7e-36 124.2 11.9 1.6 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 GAN02368.1 - 2.7e-18 65.8 0.1 7.9e-18 64.3 0.1 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal LMBR1 PF04791.16 GAN02368.1 - 0.00049 19.1 6.6 0.001 18.1 6.6 1.8 1 1 0 1 1 1 1 LMBR1-like membrane protein Cullin_binding PF03556.15 GAN02369.1 - 5.6e-12 46.2 1.5 5.6e-12 46.2 1.5 1.9 1 1 1 2 2 2 1 Cullin binding Tma16 PF11176.8 GAN02369.1 - 0.032 14.1 0.5 0.069 13.0 0.5 1.5 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Arm PF00514.23 GAN02370.1 - 6.3e-73 238.8 24.5 4.6e-12 45.5 0.1 10.4 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAN02370.1 - 5.5e-18 65.2 12.8 5.4e-06 26.7 0.1 6.8 2 2 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 GAN02370.1 - 6.7e-18 64.8 22.1 0.00014 22.3 0.3 8.3 8 1 1 9 9 8 5 HEAT-like repeat Adaptin_N PF01602.20 GAN02370.1 - 1.3e-14 53.7 10.0 1.4e-10 40.4 0.7 2.3 1 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 GAN02370.1 - 1.8e-12 46.4 17.9 0.38 11.1 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat KAP PF05804.12 GAN02370.1 - 6.1e-12 44.5 2.4 1.7e-11 43.1 2.4 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 GAN02370.1 - 5.5e-11 42.4 8.0 8.4e-07 28.7 1.5 3.0 1 1 1 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.14 GAN02370.1 - 7.4e-07 28.8 5.1 0.0053 16.1 0.8 3.5 1 1 1 2 2 2 2 V-ATPase subunit H Cnd1 PF12717.7 GAN02370.1 - 1.4e-06 28.5 7.5 0.0075 16.3 1.1 4.9 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 GAN02370.1 - 4.5e-06 26.7 4.7 0.097 12.6 0.1 3.7 2 2 1 3 3 3 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 GAN02370.1 - 0.00017 21.7 8.2 0.94 9.6 0.3 5.8 3 2 3 6 6 6 3 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 GAN02370.1 - 0.0024 18.4 0.3 31 5.3 0.0 4.3 2 2 2 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 GAN02370.1 - 0.0096 16.1 1.4 3 8.1 0.0 3.6 2 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTTN_N PF14726.6 GAN02370.1 - 0.014 16.1 0.4 0.69 10.7 0.0 3.2 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Atx10homo_assoc PF09759.9 GAN02370.1 - 0.093 12.8 5.0 0.8 9.8 0.2 3.9 3 2 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 GAN02370.1 - 0.16 11.9 7.2 4.6 7.2 0.0 4.0 3 2 2 5 5 5 0 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.16 GAN02370.1 - 0.27 12.0 13.2 1e+02 4.0 0.0 7.4 7 1 0 7 7 6 0 PBS lyase HEAT-like repeat Sec62 PF03839.16 GAN02371.1 - 1.1e-48 165.6 4.3 3.1e-48 164.2 4.1 1.6 1 1 0 1 1 1 1 Translocation protein Sec62 Tfb4 PF03850.14 GAN02372.1 - 2.2e-92 309.5 0.6 2.7e-92 309.2 0.6 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Phosducin PF02114.16 GAN02373.1 - 1.7e-20 73.1 0.6 2.1e-20 72.8 0.6 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 GAN02373.1 - 0.00017 21.5 0.1 0.00033 20.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin ADH_zinc_N PF00107.26 GAN02374.1 - 2.8e-06 27.4 0.0 2.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sm_like PF16243.5 GAN02374.1 - 0.057 13.6 0.0 0.059 13.5 0.0 1.1 1 0 0 1 1 1 0 Sm_like domain MucB_RseB PF03888.14 GAN02375.1 - 0.022 14.3 0.2 0.046 13.3 0.1 1.6 2 0 0 2 2 2 0 MucB/RseB N-terminal domain MFS_1 PF07690.16 GAN02376.1 - 3.1e-05 23.1 9.2 3.2e-05 23.0 9.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 GAN02377.1 - 0.023 13.6 13.4 0.026 13.4 13.4 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily KleE PF17394.2 GAN02377.1 - 0.064 13.5 0.4 0.13 12.5 0.2 1.6 1 1 1 2 2 2 0 Uncharacterized KleE stable inheritance protein DUF308 PF03729.13 GAN02377.1 - 1.8 8.9 10.6 46 4.4 5.3 2.5 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DnaG_DnaB_bind PF08278.11 GAN02378.1 - 0.046 14.3 0.0 0.21 12.2 0.0 2.1 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding PI3_PI4_kinase PF00454.27 GAN02379.1 - 2.3e-52 178.3 0.0 6.5e-52 176.8 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 GAN02379.1 - 1.1e-36 126.5 2.3 2.1e-34 119.0 1.9 3.1 2 1 0 2 2 2 2 Serine/threonine-protein kinase smg-1 FATC PF02260.20 GAN02379.1 - 3.7e-12 45.8 0.2 8.5e-12 44.7 0.2 1.7 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 GAN02379.1 - 0.00014 22.2 4.0 0.078 13.4 0.2 3.2 1 1 1 2 2 2 2 FKBP12-rapamycin binding domain Opi1 PF08618.10 GAN02380.1 - 3.6e-45 155.0 8.8 1.1e-38 133.6 5.1 2.2 1 1 1 2 2 2 2 Transcription factor Opi1 Ery_res_leader2 PF08057.11 GAN02380.1 - 0.12 12.8 0.5 0.6 10.7 0.5 2.2 1 0 0 1 1 1 0 Erythromycin resistance leader peptide Alpha_E1_glycop PF01589.16 GAN02381.1 - 1.7 7.2 13.0 0.13 10.9 2.5 2.0 1 1 1 2 2 2 0 Alphavirus E1 glycoprotein NDUF_B4 PF07225.12 GAN02384.1 - 0.017 15.0 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-gamma PF00631.22 GAN02385.1 - 4e-23 81.2 0.0 4.7e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 GGL domain Aconitase PF00330.20 GAN02386.1 - 1.5e-111 373.7 0.1 1.6e-110 370.3 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAN02386.1 - 7.6e-22 78.0 0.0 1.7e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 GAN02386.1 - 0.00018 20.4 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) COPIIcoated_ERV PF07970.12 GAN02387.1 - 1.7e-76 256.9 0.0 2.1e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAN02387.1 - 2.1e-30 104.9 0.1 3.9e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SET PF00856.28 GAN02388.1 - 1.1e-08 35.7 2.6 5.1e-08 33.5 2.6 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAN02388.1 - 2.1e-06 27.7 8.0 2.1e-06 27.7 8.0 3.4 2 1 1 3 3 3 1 MYND finger zf-Mss51 PF13824.6 GAN02388.1 - 1.6 8.9 18.2 0.92 9.7 5.1 3.8 3 1 1 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc-ribbons_6 PF07191.12 GAN02388.1 - 9.9 6.2 24.0 4.1 7.5 2.2 3.3 3 0 0 3 3 3 0 zinc-ribbons SPRY PF00622.28 GAN02390.1 - 1.4e-24 86.5 0.2 3.3e-24 85.3 0.2 1.7 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 GAN02390.1 - 1.9e-21 76.5 0.1 3e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAN02390.1 - 9.2e-06 25.4 0.0 2.8e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 LisH MitMem_reg PF13012.6 GAN02390.1 - 0.1 13.0 0.2 29 5.1 0.1 2.7 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Ribosomal_L3 PF00297.22 GAN02391.1 - 2.1e-18 66.5 3.6 1.2e-15 57.4 0.5 2.6 1 1 2 3 3 3 2 Ribosomal protein L3 Zn_clus PF00172.18 GAN02392.1 - 8.9e-11 41.7 12.2 1.7e-10 40.8 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isy1 PF06246.12 GAN02392.1 - 0.93 9.0 30.6 2 7.9 3.2 2.3 2 0 0 2 2 2 0 Isy1-like splicing family Exonuc_VII_L PF02601.15 GAN02392.1 - 1 8.9 40.0 0.28 10.7 6.6 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit PAT1 PF09770.9 GAN02392.1 - 4.4 5.5 76.4 0.54 8.5 22.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.7 GAN02394.1 - 6.2e-08 32.4 0.2 4.8e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 F-box-like Usp PF00582.26 GAN02397.1 - 4.1e-12 46.8 0.1 5.8e-11 43.1 0.1 2.0 1 1 0 1 1 1 1 Universal stress protein family Amidohydro_3 PF07969.11 GAN02397.1 - 0.078 12.4 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family Pkinase PF00069.25 GAN02398.1 - 2.8e-72 243.2 0.0 5.1e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02398.1 - 1.3e-47 162.2 0.0 2.2e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAN02398.1 - 9.9e-22 77.1 1.6 2e-21 76.1 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAN02398.1 - 5.2e-06 25.5 1.6 1e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN02398.1 - 4.5e-05 22.9 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN02398.1 - 0.0084 15.5 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN02398.1 - 0.024 14.5 0.1 0.6 10.0 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 GAN02398.1 - 0.038 13.6 0.5 0.074 12.7 0.1 1.6 2 0 0 2 2 2 0 DSHCT (NUC185) domain FTA2 PF13095.6 GAN02398.1 - 0.061 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Med8 PF10232.9 GAN02399.1 - 2.8e-06 27.1 7.9 6.9e-06 25.8 7.9 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 efThoc1 PF11957.8 GAN02399.1 - 0.0095 14.7 0.4 0.0095 14.7 0.4 2.3 1 1 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Kinesin PF00225.23 GAN02400.1 - 2.6e-113 378.3 0.0 4.3e-113 377.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 GAN02400.1 - 4.1e-61 206.3 1.2 4.1e-61 206.3 1.2 2.1 2 0 0 2 2 2 1 Kinesin-associated DUF3694 PF12473.8 GAN02400.1 - 4.2e-30 105.4 0.4 1.3e-29 103.9 0.4 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 GAN02400.1 - 1e-26 93.7 0.0 2.9e-26 92.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 GAN02400.1 - 2.3e-09 37.7 0.3 7.8e-09 36.0 0.3 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.26 GAN02400.1 - 0.00083 19.7 0.1 0.0064 16.8 0.1 2.6 2 0 0 2 2 2 1 FHA domain SUIM_assoc PF16619.5 GAN02400.1 - 0.011 15.8 0.0 0.011 15.8 0.0 3.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF1547 PF07577.11 GAN02400.1 - 0.086 13.2 0.2 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) F-box PF00646.33 GAN02401.1 - 1.1e-05 25.1 0.0 0.00015 21.5 0.0 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAN02401.1 - 0.00015 21.6 0.1 0.00043 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like EIAV_Rev PF11129.8 GAN02401.1 - 0.14 12.4 0.0 9.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus LRR_2 PF07723.13 GAN02401.1 - 2 9.2 0.0 2 9.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat E1-E2_ATPase PF00122.20 GAN02402.1 - 1.6e-24 86.4 0.1 4.4e-24 85.0 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAN02402.1 - 1.1e-08 35.6 0.0 0.0032 17.8 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN02402.1 - 0.00017 21.2 0.0 0.00017 21.2 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAN02402.1 - 0.00036 20.5 0.0 0.00087 19.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Ctr PF04145.15 GAN02402.1 - 0.0054 17.4 0.1 0.016 15.8 0.1 1.8 1 0 0 1 1 1 1 Ctr copper transporter family PgaD PF13994.6 GAN02402.1 - 0.035 14.2 0.8 0.67 10.0 0.0 2.9 3 0 0 3 3 3 0 PgaD-like protein Hydrolase_3 PF08282.12 GAN02402.1 - 0.094 12.4 0.5 0.41 10.3 0.1 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase NAC PF01849.18 GAN02403.1 - 3.6e-18 65.3 0.4 6.1e-17 61.4 0.1 2.3 2 0 0 2 2 2 1 NAC domain Nmad3 PF18754.1 GAN02403.1 - 0.06 12.9 0.1 0.07 12.7 0.1 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 DUF702 PF05142.12 GAN02403.1 - 0.17 12.4 0.8 0.24 11.9 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF1727 PF08353.10 GAN02403.1 - 0.3 11.0 2.4 0.64 10.0 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1727) Chalcone_2 PF16035.5 GAN02404.1 - 4.5e-38 131.1 1.4 1e-36 126.7 1.4 2.1 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 GAN02404.1 - 4.9e-08 33.3 0.3 0.00012 22.2 0.1 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like GDPD_2 PF13653.6 GAN02404.1 - 0.021 15.3 0.2 0.07 13.6 0.2 2.0 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Chalcone PF02431.15 GAN02404.1 - 0.024 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Isy1 PF06246.12 GAN02405.1 - 1.5e-92 309.7 8.2 1.8e-92 309.5 8.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family PTPS PF01242.19 GAN02406.1 - 1.8e-33 115.2 0.5 2.2e-33 114.8 0.5 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF4899 PF16240.5 GAN02406.1 - 0.058 12.6 0.1 0.099 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) Peptidase_S15 PF02129.18 GAN02407.1 - 6.3e-06 26.0 0.0 7.4e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAN02407.1 - 0.0063 16.2 0.3 0.024 14.3 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN02407.1 - 0.023 14.0 0.0 0.054 12.7 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 VirJ PF06057.11 GAN02407.1 - 0.036 13.9 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) BAR PF03114.18 GAN02408.1 - 4.3e-35 121.5 8.4 7.1e-35 120.8 8.4 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAN02408.1 - 3.7e-15 55.3 0.1 7.1e-15 54.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN02408.1 - 5.4e-14 51.8 0.2 2.6e-13 49.6 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAN02408.1 - 2.9e-13 49.3 0.1 4.9e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 GAN02408.1 - 3.7e-06 26.3 2.6 7.3e-06 25.3 2.6 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking YebG PF07130.12 GAN02408.1 - 0.16 11.9 2.0 8.1 6.4 0.0 2.5 2 0 0 2 2 2 0 YebG protein OmpH PF03938.14 GAN02408.1 - 2.5 8.4 12.2 0.88 9.9 9.1 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 GAN02409.1 - 0 1059.9 0.9 0 1059.5 0.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF641 PF04859.12 GAN02409.1 - 0.022 15.1 0.8 0.059 13.7 0.8 1.8 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ATG16 PF08614.11 GAN02409.1 - 0.54 10.5 7.3 0.051 13.8 2.0 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 GAN02409.1 - 1.3 9.2 4.5 0.9 9.7 1.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor HWE_HK PF07536.14 GAN02409.1 - 1.6 9.5 4.8 2.2 9.1 0.8 2.6 2 0 0 2 2 2 0 HWE histidine kinase CCDC-167 PF15188.6 GAN02409.1 - 2.1 8.7 4.2 0.85 10.0 0.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ACT_7 PF13840.6 GAN02411.1 - 1.4e-21 76.1 0.0 2e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 ACT domain WD40 PF00400.32 GAN02412.1 - 3.9e-34 116.1 31.3 2e-05 25.2 0.9 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02412.1 - 3e-18 65.9 2.9 0.022 15.1 0.0 6.5 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAN02412.1 - 3e-09 36.6 0.5 5.8e-09 35.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 GAN02412.1 - 4.7e-08 32.7 0.1 0.0024 17.3 0.0 2.3 1 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 GAN02412.1 - 1.8e-05 23.6 6.3 0.79 8.3 0.1 5.2 3 2 2 5 5 5 4 Nucleoporin Nup120/160 PQQ_3 PF13570.6 GAN02412.1 - 0.00019 21.8 3.3 16 6.2 0.0 5.9 5 2 2 7 7 7 1 PQQ-like domain F-box PF00646.33 GAN02412.1 - 0.0019 18.0 1.2 0.0043 16.9 0.8 1.8 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.6 GAN02412.1 - 0.023 14.3 2.2 1.8 8.1 0.3 2.8 1 1 0 2 2 2 0 PQQ-like domain DUF4934 PF16288.5 GAN02412.1 - 0.11 12.5 0.2 0.46 10.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4934) Sulfate_transp PF00916.20 GAN02413.1 - 3.5e-96 322.3 22.7 4.7e-96 321.8 22.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN02413.1 - 9.1e-22 76.9 0.0 1.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN02413.1 - 0.00042 20.7 5.3 0.00042 20.7 5.3 3.3 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 GAN02413.1 - 0.02 15.2 0.1 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 STAS domain TMEM174 PF15029.6 GAN02413.1 - 0.022 14.5 1.5 0.059 13.1 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 174 DUF373 PF04123.13 GAN02413.1 - 6.9 6.0 16.1 1.1 8.6 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Methyltransf_16 PF10294.9 GAN02414.1 - 4.5e-44 150.2 0.0 6.3e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAN02414.1 - 0.00019 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAN02414.1 - 0.00021 21.2 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAN02414.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 GAN02414.1 - 0.0059 16.4 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 GAN02414.1 - 0.0093 15.1 0.0 0.02 13.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 GAN02414.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 GAN02414.1 - 0.044 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 GAN02414.1 - 0.052 14.3 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Chalcone_N PF18232.1 GAN02414.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Chalcone isomerase N-terminal domain MWFE PF15879.5 GAN02415.1 - 3.9e-24 84.6 0.1 5e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Maf PF02545.14 GAN02416.1 - 1.3e-48 164.9 0.1 1.6e-48 164.7 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein Tipalpha PF16753.5 GAN02416.1 - 0.076 12.8 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter zf-C2H2 PF00096.26 GAN02417.1 - 1.2e-07 31.8 26.3 8.7e-05 22.8 0.3 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN02417.1 - 1.5e-05 25.2 24.2 0.00027 21.2 1.6 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN02417.1 - 0.00021 21.9 22.6 0.12 13.3 0.2 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAN02417.1 - 0.00061 20.0 6.2 1.1 9.6 5.8 3.1 2 1 1 3 3 3 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAN02417.1 - 0.0057 17.3 13.3 0.022 15.4 0.1 4.3 1 1 3 4 4 4 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 GAN02417.1 - 0.48 10.5 11.0 12 6.1 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf_ZIC PF18366.1 GAN02417.1 - 3.1 8.0 10.7 0.94 9.6 0.1 4.0 2 1 1 3 3 3 0 Zic proteins zinc finger domain Zap1_zf2 PF18217.1 GAN02417.1 - 4.1 7.5 8.4 5.6 7.1 0.7 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 Pkinase PF00069.25 GAN02418.1 - 1.4e-68 231.2 0.0 2.3e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02418.1 - 4.5e-51 173.6 0.0 1.6e-50 171.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Asp_protease PF09668.10 GAN02418.1 - 9.9e-50 167.5 0.0 1.7e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAN02418.1 - 1.9e-18 66.8 0.1 4.5e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 GAN02418.1 - 5e-14 51.8 0.2 1.1e-13 50.7 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 GAN02418.1 - 3e-08 34.2 0.1 8e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Rad60-SLD PF11976.8 GAN02418.1 - 1.5e-05 24.7 0.1 3.1e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 GAN02418.1 - 0.00012 21.7 0.7 0.00012 21.7 0.7 2.5 2 0 0 2 2 2 1 XPC-binding domain RVP PF00077.20 GAN02418.1 - 0.00013 22.2 0.0 0.00036 20.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Ubiquitin_2 PF14560.6 GAN02418.1 - 0.00024 21.5 0.0 0.00073 19.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain Pkinase_fungal PF17667.1 GAN02418.1 - 0.0006 18.7 1.8 0.00062 18.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN02418.1 - 0.0035 16.7 0.0 0.044 13.1 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAN02418.1 - 0.045 12.7 1.0 6.1 5.7 0.0 2.8 3 0 0 3 3 3 0 Haspin like kinase domain RVP_2 PF08284.11 GAN02418.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Ubiquitin_4 PF18036.1 GAN02418.1 - 0.078 13.0 0.1 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain UBA PF00627.31 GAN02418.1 - 0.085 12.8 1.4 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain Abi_2 PF07751.11 GAN02418.1 - 0.11 12.8 0.2 0.8 9.9 0.0 2.4 2 0 0 2 2 2 0 Abi-like protein MT-A70 PF05063.14 GAN02420.1 - 1.6e-33 116.0 0.5 2.3e-33 115.6 0.5 1.2 1 0 0 1 1 1 1 MT-A70 INPP5B_PH PF16776.5 GAN02420.1 - 0.053 13.2 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Glucosamine_iso PF01182.20 GAN02421.1 - 5.1e-15 56.0 0.0 3.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF4787 PF16029.5 GAN02422.1 - 1.7 8.8 10.7 2.6 8.2 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) Y_phosphatase PF00102.27 GAN02423.1 - 0.00013 21.6 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAN02423.1 - 0.0052 16.6 0.0 0.0088 15.9 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Vps39_2 PF10367.9 GAN02424.1 - 2.1e-16 60.3 1.1 5.4e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 GAN02424.1 - 3.3e-15 56.3 4.5 1e-13 51.5 1.1 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 GAN02424.1 - 1.3e-13 51.2 0.0 2.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 GAN02424.1 - 4.7e-06 26.5 8.8 0.083 12.8 0.0 4.1 4 0 0 4 4 4 3 Region in Clathrin and VPS Oxidored_q6 PF01058.22 GAN02425.1 - 6.7e-22 77.7 0.0 9.9e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Gram_pos_anchor PF00746.21 GAN02426.1 - 5.9 6.9 6.1 1.3 9.0 1.4 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Baculo_11_kDa PF06143.11 GAN02427.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family LysE PF01810.18 GAN02427.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 LysE type translocator Ribosomal_S3_C PF00189.20 GAN02428.1 - 1.9e-22 79.5 1.5 6e-22 78.0 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAN02428.1 - 1.4e-12 47.2 0.1 2.4e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GAN02428.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Metallophos PF00149.28 GAN02429.1 - 2.2e-35 123.0 0.3 2.9e-35 122.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN02429.1 - 0.039 14.4 0.2 0.08 13.4 0.2 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 GAN02429.1 - 0.058 13.0 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PHP PF02811.19 GAN02430.1 - 0.00011 22.6 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 PHP domain Ribosomal_S5_C PF03719.15 GAN02431.1 - 1.4e-24 85.3 0.1 2.1e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GAN02431.1 - 6.6e-05 22.8 0.1 0.00017 21.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 GAN02431.1 - 3.3 8.3 11.5 5.7 7.6 11.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Hid1 PF12722.7 GAN02432.1 - 1e-111 374.5 2.2 1.3e-111 374.2 2.2 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAN02432.1 - 6.2e-52 176.9 0.5 7.5e-52 176.6 0.5 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DASH_Spc19 PF08287.11 GAN02432.1 - 0.091 12.6 0.6 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Spc19 Cyt-b5 PF00173.28 GAN02434.1 - 4.8e-12 45.9 0.1 5.3e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Chorismate_bind PF00425.18 GAN02435.1 - 1.5e-97 326.2 0.0 3.2e-97 325.1 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 GAN02435.1 - 1.2e-26 93.6 0.0 1.1e-25 90.4 0.0 2.6 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Hid1 PF12722.7 GAN02436.1 - 1.3e-94 318.0 6.3 1.6e-94 317.7 6.3 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAN02436.1 - 3.8e-44 151.1 0.1 4.5e-43 147.6 0.1 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SLC12 PF03522.15 GAN02436.1 - 0.0011 18.0 3.1 0.0017 17.5 3.1 1.3 1 1 0 1 1 1 1 Solute carrier family 12 TFIIA PF03153.13 GAN02436.1 - 0.45 10.5 18.5 0.4 10.6 13.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 GAN02436.1 - 0.64 10.1 30.2 1 9.5 1.4 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 GAN02436.1 - 0.68 10.9 3.2 1 10.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 GAN02436.1 - 1.2 8.7 25.1 0.084 12.5 13.8 2.3 2 0 0 2 2 2 0 Spt20 family FTZ PF03867.14 GAN02436.1 - 3.7 7.0 8.3 0.76 9.3 2.6 2.1 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region PIP5K PF01504.18 GAN02437.1 - 3.9e-25 88.6 1.2 2.6e-21 76.1 1.0 4.6 2 2 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 GAN02437.1 - 1.4e-16 60.3 15.9 1.4e-16 60.3 15.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 GAN02437.1 - 1e-14 54.1 0.0 2.1e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family IBR PF01485.21 GAN02437.1 - 0.12 12.6 16.9 4 7.7 12.2 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain COPI_C PF06957.11 GAN02438.1 - 3.9e-140 467.2 0.3 5e-140 466.8 0.3 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 GAN02438.1 - 1.1e-136 456.5 0.0 1.8e-136 455.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 GAN02438.1 - 5.6e-43 144.1 13.8 7.1e-08 33.0 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02438.1 - 5.3e-11 42.7 0.4 0.0028 17.9 0.0 6.5 4 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN02438.1 - 0.0059 15.3 10.0 0.2 10.2 0.2 4.2 2 2 2 4 4 4 2 Nucleoporin Nup120/160 SGL PF08450.12 GAN02438.1 - 0.028 14.0 0.0 1.4 8.4 0.0 3.0 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region SUIM_assoc PF16619.5 GAN02438.1 - 6.4 6.9 7.9 1.1 9.4 3.2 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 F-box-like PF12937.7 GAN02439.1 - 0.0013 18.6 0.2 0.003 17.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN02439.1 - 0.0059 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 F-box domain Abhydrolase_3 PF07859.13 GAN02440.1 - 2.3e-63 213.9 0.0 2.9e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAN02440.1 - 5.1e-08 32.2 0.1 1.6e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAN02440.1 - 2.8e-07 29.7 0.1 4.2e-07 29.2 0.1 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAN02440.1 - 1.1e-06 28.2 0.0 3e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAN02440.1 - 0.028 13.3 0.3 0.077 11.9 0.3 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.12 GAN02440.1 - 0.059 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 GAN02441.1 - 2.5e-15 56.8 0.0 9.7e-15 54.9 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN02441.1 - 1.1e-06 28.2 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN02441.1 - 0.0015 19.1 0.0 0.0026 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Nucleos_tra2_C PF07662.13 GAN02442.1 - 2.9e-72 242.9 11.8 2.9e-72 242.9 11.8 2.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 GAN02442.1 - 1.5e-23 83.1 3.9 1.5e-23 83.1 3.9 3.1 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Orf78 PF06024.12 GAN02442.1 - 0.005 17.1 0.4 0.02 15.2 0.4 2.0 1 0 0 1 1 1 1 Orf78 (ac78) Gram_pos_anchor PF00746.21 GAN02442.1 - 1.6 8.8 4.3 6.5 6.8 0.0 3.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Glycophorin_A PF01102.18 GAN02443.1 - 0.21 11.8 0.0 0.21 11.8 0.0 3.0 2 2 2 4 4 4 0 Glycophorin A Adeno_E3_CR2 PF02439.15 GAN02443.1 - 0.45 10.3 4.6 0.84 9.5 4.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SRPRB PF09439.10 GAN02444.1 - 5.3e-45 153.1 0.0 6.6e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 GAN02444.1 - 6.5e-18 64.8 0.0 9.6e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN02444.1 - 1.4e-05 25.2 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN02444.1 - 6.8e-05 22.3 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAN02444.1 - 0.00016 21.3 0.1 0.00051 19.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 GAN02444.1 - 0.0036 17.1 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 GAN02444.1 - 0.049 13.2 0.2 0.23 10.9 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Aldo_ket_red PF00248.21 GAN02445.1 - 3.4e-77 259.5 0.0 3.8e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family QueH PF02677.14 GAN02445.1 - 0.084 13.0 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Epoxyqueuosine reductase QueH Aldo_ket_red PF00248.21 GAN02446.1 - 3.5e-75 252.9 0.0 4.3e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 GAN02447.1 - 1.6e-74 250.7 0.0 2e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sel1 PF08238.12 GAN02449.1 - 7.2e-08 32.9 22.2 0.0017 19.0 0.3 6.4 7 0 0 7 7 7 2 Sel1 repeat GCV_H PF01597.19 GAN02449.1 - 0.011 15.6 0.8 0.024 14.5 0.4 1.7 2 0 0 2 2 2 0 Glycine cleavage H-protein GerE PF00196.19 GAN02449.1 - 0.063 12.8 0.1 0.2 11.2 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family TPR_12 PF13424.6 GAN02450.1 - 0.00082 19.6 2.4 0.053 13.8 1.9 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAN02450.1 - 0.033 14.1 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat T4-gp15_tss PF16724.5 GAN02450.1 - 0.081 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 T4-like virus Myoviridae tail sheath stabiliser ATP13 PF12921.7 GAN02450.1 - 0.12 12.3 0.5 2.2 8.2 0.1 2.2 1 1 1 2 2 2 0 Mitochondrial ATPase expression zf-C5HC2 PF02928.16 GAN02451.1 - 0.0013 19.1 1.2 0.51 10.8 0.1 2.2 2 0 0 2 2 2 2 C5HC2 zinc finger zf-C2H2_jaz PF12171.8 GAN02452.1 - 0.00084 19.6 1.1 0.28 11.5 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAN02452.1 - 0.002 18.5 3.6 0.54 10.8 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN02452.1 - 0.014 16.2 4.2 1 10.4 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger LIM PF00412.22 GAN02452.1 - 0.047 13.9 1.8 0.13 12.5 1.7 1.7 1 1 0 1 1 1 0 LIM domain zf-FCS PF06467.14 GAN02452.1 - 0.33 10.9 4.9 8.5 6.4 0.6 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif SPOB_ab PF14682.6 GAN02453.1 - 0.0062 16.6 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal TetR_C_1 PF02909.17 GAN02453.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Homeobox_KN PF05920.11 GAN02455.1 - 4.5e-19 68.1 0.8 1.4e-18 66.5 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 GAN02455.1 - 1.2e-05 25.0 0.1 2.9e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Homeodomain TLP-20 PF06088.11 GAN02455.1 - 0.00047 20.1 1.2 0.018 14.9 0.1 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ANAPC1 PF12859.7 GAN02455.1 - 0.019 15.5 2.1 0.071 13.7 2.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 CDC45 PF02724.14 GAN02455.1 - 0.18 10.1 5.1 0.45 8.7 1.6 2.0 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.6 GAN02455.1 - 0.69 9.6 6.5 2.4 7.8 0.7 2.2 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 GAN02455.1 - 6 7.3 13.6 3.1 8.2 7.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAN02455.1 - 9.2 6.7 16.7 0.7 10.3 7.6 2.8 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CBM_21 PF03370.13 GAN02456.1 - 2.1e-31 108.4 1.7 5.9e-31 107.0 1.7 1.8 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAN02456.1 - 1.5e-10 41.5 2.8 4.3e-10 40.0 2.8 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) GTSE1_N PF15259.6 GAN02456.1 - 0.013 15.7 1.8 0.036 14.3 1.8 1.8 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Wbp11 PF09429.10 GAN02457.1 - 4.5e-22 78.2 12.4 4.5e-22 78.2 12.4 1.9 2 0 0 2 2 2 1 WW domain binding protein 11 DNA_pol_phi PF04931.13 GAN02457.1 - 0.1 10.7 10.1 0.2 9.7 10.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi TRIQK PF15168.6 GAN02457.1 - 0.19 11.7 2.8 0.38 10.7 2.8 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Pkinase PF00069.25 GAN02458.1 - 2.6e-64 217.2 0.5 5.3e-63 212.8 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02458.1 - 5.1e-27 94.8 8.2 1.7e-22 79.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN02458.1 - 3e-07 29.7 0.1 3e-07 29.7 0.1 2.1 1 1 1 2 2 1 1 Haspin like kinase domain TFIIA PF03153.13 GAN02458.1 - 0.00021 21.4 29.2 0.00029 20.9 29.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kdo PF06293.14 GAN02458.1 - 0.0014 18.0 0.0 0.0014 18.0 0.0 2.4 3 0 0 3 3 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN02458.1 - 0.0014 18.6 7.2 0.078 12.9 0.3 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAN02458.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 GAN02458.1 - 0.02 15.6 0.4 0.02 15.6 0.4 2.0 2 0 0 2 2 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 GAN02458.1 - 0.033 13.2 0.2 0.058 12.4 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 GAN02458.1 - 1.6 7.4 12.3 4.5 6.0 12.3 1.7 1 1 0 1 1 1 0 Fungal protein kinase Med15 PF09606.10 GAN02458.1 - 2.3 6.8 32.7 2.9 6.5 32.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HD PF01966.22 GAN02459.1 - 2.7e-10 40.5 0.4 4.3e-10 39.9 0.4 1.3 1 0 0 1 1 1 1 HD domain FHA PF00498.26 GAN02460.1 - 2.5e-15 56.6 1.9 8.5e-15 54.9 0.1 2.6 3 0 0 3 3 2 1 FHA domain zf-RING_11 PF17123.5 GAN02460.1 - 7.6e-11 41.6 7.2 7.6e-11 41.6 7.2 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 GAN02460.1 - 1.1e-08 35.3 7.9 2.6e-08 34.0 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN02460.1 - 9.5e-05 22.2 9.2 0.00019 21.2 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN02460.1 - 0.00015 22.0 7.3 0.00047 20.4 7.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAN02460.1 - 0.00036 20.4 7.8 0.00073 19.3 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN02460.1 - 0.00093 19.1 7.3 0.002 18.1 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN02460.1 - 0.0017 18.2 4.2 0.0032 17.3 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 GAN02460.1 - 0.045 13.7 3.9 0.091 12.7 3.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 GAN02460.1 - 0.052 13.6 11.3 0.13 12.3 11.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAN02460.1 - 0.092 12.8 2.7 0.24 11.5 2.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sec_GG PF07549.14 GAN02460.1 - 0.15 11.6 0.1 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif YpjP PF14005.6 GAN02461.1 - 0.59 10.2 8.9 2.4 8.2 0.7 3.1 2 1 2 4 4 4 0 YpjP-like protein pP_pnuc_2 PF18166.1 GAN02461.1 - 5.1 7.2 9.4 2.8 8.0 1.3 3.3 2 1 1 4 4 4 0 Predicted pPIWI-associating nuclease FYVE PF01363.21 GAN02462.1 - 1.2e-14 54.2 7.4 3.9e-14 52.5 7.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger Hom_end PF05204.14 GAN02462.1 - 0.021 15.0 0.5 0.055 13.6 0.5 1.7 1 0 0 1 1 1 0 Homing endonuclease AIG1 PF04548.16 GAN02462.1 - 0.066 12.5 2.6 0.13 11.6 2.6 1.4 1 0 0 1 1 1 0 AIG1 family ALS2CR11 PF15729.5 GAN02462.1 - 1.2 8.3 7.9 1.7 7.7 7.9 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 SSB PF00436.25 GAN02463.1 - 7.4e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Kelch_5 PF13854.6 GAN02464.1 - 1.7e-07 31.1 0.0 0.024 14.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAN02464.1 - 7.6e-06 25.8 6.0 5 7.2 0.0 5.8 5 1 0 5 5 5 2 Galactose oxidase, central domain Phage_holin_2_4 PF16082.5 GAN02464.1 - 2.6e-05 23.9 0.1 4.9e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like Kelch_6 PF13964.6 GAN02464.1 - 0.0001 22.5 1.6 29 5.1 0.0 5.4 5 0 0 5 5 5 0 Kelch motif VSP PF03302.13 GAN02464.1 - 0.00026 20.0 0.1 0.00026 20.0 0.1 1.8 2 0 0 2 2 2 1 Giardia variant-specific surface protein Kelch_1 PF01344.25 GAN02464.1 - 0.012 15.2 4.4 0.16 11.5 0.1 4.1 5 0 0 5 5 5 0 Kelch motif LapA_dom PF06305.11 GAN02464.1 - 0.014 15.1 0.2 0.032 14.0 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 GAN02464.1 - 0.028 13.4 0.0 0.27 10.1 0.0 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 GAN02464.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Halogen_Hydrol PF10112.9 GAN02464.1 - 0.065 13.3 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YebO PF13974.6 GAN02464.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 YebO-like protein DUF2681 PF10883.8 GAN02464.1 - 0.11 13.0 0.3 0.21 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 GAN02464.1 - 0.13 13.1 1.1 0.33 11.8 0.0 2.2 3 0 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 GAN02464.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A PhoLip_ATPase_C PF16212.5 GAN02465.1 - 2e-81 273.4 29.0 2e-81 273.4 29.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal adh_short PF00106.25 GAN02465.1 - 6.9e-52 175.7 1.7 1.5e-51 174.7 1.7 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN02465.1 - 6.7e-48 163.3 0.7 1.4e-47 162.2 0.7 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PhoLip_ATPase_N PF16209.5 GAN02465.1 - 1.2e-24 85.7 1.9 4.1e-24 84.0 1.9 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal KR PF08659.10 GAN02465.1 - 7.5e-15 55.3 1.3 2e-14 53.9 1.3 1.7 1 0 0 1 1 1 1 KR domain Hydrolase PF00702.26 GAN02465.1 - 4.7e-13 49.9 0.8 5.7e-08 33.3 0.2 3.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN02465.1 - 3e-11 43.2 0.0 1.3e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAN02465.1 - 4.2e-10 39.4 0.0 1.3e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Epimerase PF01370.21 GAN02465.1 - 5.3e-06 26.1 0.3 1.3e-05 24.8 0.3 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAN02465.1 - 0.00033 19.9 0.2 0.00076 18.7 0.2 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Hydrolase_3 PF08282.12 GAN02465.1 - 0.00084 19.2 0.1 0.018 14.8 0.0 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Protoglobin PF11563.8 GAN02466.1 - 5.8e-43 146.5 0.0 7e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Protoglobin VTC PF09359.10 GAN02467.1 - 3.4e-102 341.5 0.1 3.4e-102 341.5 0.1 1.7 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAN02467.1 - 1.9e-16 60.3 2.5 3.9e-16 59.3 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 GAN02467.1 - 6.2e-09 36.3 11.5 6.7e-06 26.3 0.2 3.4 3 0 0 3 3 3 2 SPX domain EnY2 PF10163.9 GAN02467.1 - 0.4 11.1 2.6 0.78 10.2 0.5 2.4 2 0 0 2 2 2 0 Transcription factor e(y)2 TPR_1 PF00515.28 GAN02468.1 - 1.5e-24 84.8 0.0 3.8e-08 32.8 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAN02468.1 - 1.3e-21 77.0 1.2 4.2e-07 30.5 0.0 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAN02468.1 - 3.1e-21 73.7 0.1 6.2e-06 25.9 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAN02468.1 - 5.2e-19 67.7 0.1 2.4e-06 27.1 0.0 4.6 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.6 GAN02468.1 - 5.7e-17 61.0 5.8 0.00088 19.9 0.1 5.7 4 2 2 6 6 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAN02468.1 - 5.2e-15 54.7 0.5 0.0012 19.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAN02468.1 - 9.9e-15 53.5 0.0 0.00076 19.5 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAN02468.1 - 1.3e-13 51.2 0.7 4e-06 27.3 0.4 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 GAN02468.1 - 4.7e-09 36.5 0.2 0.002 18.4 0.1 4.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAN02468.1 - 1.2e-08 34.3 0.2 0.23 11.6 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN02468.1 - 1.4e-08 34.8 0.4 0.015 15.6 0.2 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN02468.1 - 4.3e-08 33.3 0.1 3 8.7 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN02468.1 - 3.2e-07 30.5 0.2 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GAN02468.1 - 3.8e-07 30.1 0.6 0.12 12.5 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN02468.1 - 0.0078 15.5 1.3 0.89 8.7 1.3 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF1641 PF07849.11 GAN02468.1 - 0.019 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4248 PF14053.6 GAN02468.1 - 0.025 14.6 0.2 0.11 12.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4248) MIT PF04212.18 GAN02468.1 - 0.032 14.3 0.0 3.7 7.7 0.0 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 GAN02468.1 - 0.037 14.0 0.0 18 5.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAN02468.1 - 0.048 13.5 1.7 2 8.4 0.5 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAN02468.1 - 0.1 12.0 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 GAN02468.1 - 0.2 11.8 2.1 37 4.5 0.0 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat PAP_central PF04928.17 GAN02469.1 - 7.8e-113 375.5 0.0 1.1e-112 375.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAN02469.1 - 3e-47 160.4 0.3 1e-46 158.7 0.3 1.9 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAN02469.1 - 1.6e-10 41.1 0.0 6.3e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain DUF1495 PF07381.11 GAN02469.1 - 0.062 13.1 0.1 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Winged helix DNA-binding domain (DUF1495) DUF2250 PF10007.9 GAN02469.1 - 0.098 12.8 0.3 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) zf-CRD PF17979.1 GAN02471.1 - 4.7e-13 49.5 5.1 3.4e-12 46.7 5.2 2.3 1 1 0 1 1 1 1 Cysteine rich domain with multizinc binding regions Usp PF00582.26 GAN02472.1 - 1.8e-06 28.5 0.0 2.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family DpaA_N PF16924.5 GAN02472.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Tim29 PF10171.9 GAN02472.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Cnd3 PF12719.7 GAN02473.1 - 0.051 12.8 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain RasGEF PF00617.19 GAN02474.1 - 8.5e-43 146.6 0.0 2e-42 145.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Psu PF07455.11 GAN02474.1 - 0.087 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) c-SKI_SMAD_bind PF08782.10 GAN02475.1 - 0.15 12.3 1.0 0.34 11.2 0.3 1.9 2 0 0 2 2 2 0 c-SKI Smad4 binding domain NAD_binding_10 PF13460.6 GAN02476.1 - 3.3e-06 27.1 0.0 0.00024 21.0 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAN02476.1 - 7.1e-05 22.4 0.0 0.00035 20.1 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAN02476.1 - 0.00027 20.2 0.5 0.034 13.3 0.0 2.7 3 0 0 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 GAN02476.1 - 0.0018 17.3 0.0 0.059 12.4 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAN02476.1 - 0.023 13.8 0.1 0.12 11.5 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 GAN02476.1 - 0.039 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase N6-adenineMlase PF10237.9 GAN02476.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase tRNA-synt_1 PF00133.22 GAN02477.1 - 1.6e-213 710.4 0.0 1.9e-212 706.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAN02477.1 - 5.2e-34 117.4 0.3 5.2e-34 117.4 0.3 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAN02477.1 - 1.6e-15 56.8 0.0 3e-08 32.8 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAN02477.1 - 5e-08 32.7 8.0 4.5e-07 29.6 0.1 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAN02477.1 - 0.037 13.4 0.1 0.71 9.2 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 GAN02477.1 - 0.084 12.2 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) WD40 PF00400.32 GAN02478.1 - 5.1e-22 77.8 15.6 8.4e-05 23.3 1.2 11.2 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02478.1 - 0.0028 17.9 0.1 16 5.9 0.0 4.9 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAN02478.1 - 0.014 14.2 0.4 18 3.9 0.0 4.3 4 1 0 4 4 4 0 Nup133 N terminal like Ribosomal_L36 PF00444.18 GAN02479.1 - 6.1e-19 67.9 10.6 8e-19 67.6 10.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 HSP20 PF00011.21 GAN02481.1 - 1.1e-21 76.9 2.2 4.6e-13 49.2 0.1 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAN02481.1 - 1.4e-10 40.6 0.0 3.7e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA p450 PF00067.22 GAN02482.1 - 2.2e-74 250.9 0.0 3.5e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAN02483.1 - 3.3e-81 273.4 0.1 4e-81 273.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5052 PF16475.5 GAN02484.1 - 0.027 14.1 0.8 0.054 13.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) CK_II_beta PF01214.18 GAN02485.1 - 1e-82 276.4 0.1 1.3e-82 276.1 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 GAN02485.1 - 0.016 15.2 0.1 0.035 14.2 0.1 1.6 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Glyco_hydro_100 PF12899.7 GAN02485.1 - 0.031 13.0 0.1 0.045 12.4 0.1 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase SH3_14 PF18343.1 GAN02485.1 - 0.12 12.5 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Dda helicase SH3 domain MDM31_MDM32 PF08118.11 GAN02487.1 - 6.5e-171 569.6 0.0 2.2e-170 567.8 0.0 1.7 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HORMA PF02301.18 GAN02488.1 - 0.00082 19.0 0.3 0.0014 18.3 0.3 1.5 1 1 0 1 1 1 1 HORMA domain DUF2682 PF10909.8 GAN02488.1 - 0.078 13.5 1.4 0.52 10.8 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2682) Retrotrans_gag PF03732.17 GAN02489.1 - 0.0011 19.3 0.1 0.0033 17.7 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Sec7 PF01369.20 GAN02490.1 - 2.1e-35 122.1 0.2 3.7e-35 121.3 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 GAN02490.1 - 9.7e-14 51.8 0.0 9.3e-13 48.6 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAN02490.1 - 1.7e-08 34.9 0.2 4.6e-06 27.1 0.0 3.1 3 0 0 3 3 3 1 PH domain SUIM_assoc PF16619.5 GAN02490.1 - 0.001 19.1 6.6 0.26 11.4 1.2 3.1 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Inj_translocase PF16928.5 GAN02490.1 - 5.6 6.4 8.3 1.4 8.3 1.0 2.4 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome MgsA_C PF12002.8 GAN02491.1 - 1.3e-59 200.9 0.0 1.9e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 GAN02491.1 - 8.2e-26 90.2 0.3 1.7e-25 89.1 0.3 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 GAN02491.1 - 2.9e-16 60.1 0.1 7.9e-16 58.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAN02491.1 - 5e-12 45.9 0.0 8.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAN02491.1 - 4.5e-07 29.9 0.0 1.6e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN02491.1 - 1.1e-05 25.9 0.5 0.013 15.9 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 GAN02491.1 - 1.3e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAN02491.1 - 2.3e-05 24.1 0.0 0.00044 20.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 GAN02491.1 - 0.0006 19.1 0.0 0.00099 18.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 GAN02491.1 - 0.00076 20.0 0.0 0.002 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-WRNIP1_ubi PF18279.1 GAN02491.1 - 0.00092 19.7 1.4 0.0029 18.1 1.4 1.9 1 0 0 1 1 1 1 Werner helicase-interacting protein 1 ubiquitin-binding domain AAA_22 PF13401.6 GAN02491.1 - 0.0011 19.3 0.2 0.027 14.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAN02491.1 - 0.0011 18.9 0.1 1.2 8.9 0.0 2.5 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea Rad17 PF03215.15 GAN02491.1 - 0.0018 18.2 0.1 0.0063 16.5 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 GAN02491.1 - 0.0029 17.0 0.1 0.089 12.2 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 GAN02491.1 - 0.0044 16.5 0.0 0.066 12.6 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.27 GAN02491.1 - 0.0048 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_2 PF07724.14 GAN02491.1 - 0.0061 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 GAN02491.1 - 0.011 16.1 0.0 0.041 14.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 GAN02491.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 GAN02491.1 - 0.012 15.9 0.3 0.62 10.4 0.2 2.1 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAN02491.1 - 0.012 15.3 0.6 0.021 14.6 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 GAN02491.1 - 0.016 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 GAN02491.1 - 0.022 14.8 0.1 3.5 7.6 0.1 2.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 GAN02491.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 GAN02491.1 - 0.031 14.4 0.1 0.065 13.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate kinase TRAF6_Z2 PF18048.1 GAN02491.1 - 0.052 13.6 1.8 2.9 8.1 0.8 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 AAA_30 PF13604.6 GAN02491.1 - 0.079 12.7 0.0 0.33 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAN02491.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 GAN02491.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain F-box-like PF12937.7 GAN02494.1 - 0.0028 17.5 1.9 0.003 17.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like Fer2 PF00111.27 GAN02495.1 - 1.1e-10 41.3 3.1 1.4e-10 40.9 3.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GDPD PF03009.17 GAN02496.1 - 7.2e-65 219.3 0.0 6.9e-64 216.1 0.0 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 GAN02496.1 - 2.2e-28 98.6 0.2 4.3e-07 30.4 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN02496.1 - 1e-20 73.8 0.4 3.5e-07 30.6 0.0 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN02496.1 - 3.2e-19 67.0 1.6 0.013 16.0 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 GAN02496.1 - 1.7e-14 53.7 0.3 0.0034 17.7 0.0 5.8 4 1 2 6 6 6 5 Ankyrin repeats (many copies) SPX PF03105.19 GAN02496.1 - 4e-13 50.0 26.7 1.7e-07 31.5 0.0 5.2 3 2 2 5 5 5 3 SPX domain Ank PF00023.30 GAN02496.1 - 1.8e-11 43.9 4.9 0.0039 17.6 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat SBE2 PF17076.5 GAN02498.1 - 0.00093 17.6 5.8 0.00093 17.6 5.8 3.1 1 1 1 3 3 3 1 SBE2, cell-wall formation RabGAP-TBC PF00566.18 GAN02499.1 - 4.3e-23 82.1 1.4 6.1e-23 81.6 1.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ASXH PF13919.6 GAN02500.1 - 1.8e-13 50.7 0.0 5.8e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 Asx homology domain Cornifin PF02389.15 GAN02500.1 - 0.0017 18.5 2.6 0.0017 18.5 2.6 6.7 5 3 1 6 6 6 2 Cornifin (SPRR) family Glyco_trans_2_3 PF13632.6 GAN02501.1 - 7.5e-17 61.9 0.5 7.5e-17 61.9 0.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF5100 PF17029.5 GAN02501.1 - 0.057 13.3 0.8 0.14 12.0 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) RNase_PH PF01138.21 GAN02502.1 - 3.6e-25 89.0 0.0 5.6e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAN02502.1 - 5e-11 42.5 0.1 1.3e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 AMMECR1 PF01871.17 GAN02502.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AMMECR1 PQ-loop PF04193.14 GAN02503.1 - 9.8e-23 79.7 12.4 2.5e-13 49.6 1.1 3.2 3 1 0 3 3 3 2 PQ loop repeat DUF3671 PF12420.8 GAN02503.1 - 0.18 11.9 3.1 0.59 10.2 3.1 2.0 1 1 0 1 1 1 0 Protein of unknown function 4HBT PF03061.22 GAN02504.1 - 3.3e-09 37.0 0.0 6.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily PWWP PF00855.17 GAN02506.1 - 1.6e-17 63.7 0.1 1.6e-17 63.7 0.1 2.3 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 GAN02506.1 - 3.8e-08 33.2 0.0 1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CDC45 PF02724.14 GAN02506.1 - 0.0029 16.0 9.6 0.0038 15.6 9.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.11 GAN02506.1 - 0.047 11.8 9.5 0.065 11.3 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CAC1F_C PF16885.5 GAN02506.1 - 0.071 12.8 7.7 0.12 12.0 7.7 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PI3K_1B_p101 PF10486.9 GAN02506.1 - 0.11 10.3 3.6 0.12 10.2 3.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HGTP_anticodon2 PF12745.7 GAN02506.1 - 0.23 10.9 8.1 0.47 9.9 8.1 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CDC27 PF09507.10 GAN02506.1 - 1.8 7.9 22.9 2.5 7.4 22.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 GAN02506.1 - 2.4 6.8 5.7 2.9 6.6 5.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4530 PF15039.6 GAN02506.1 - 7.9 6.7 10.8 17 5.6 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Hid1 PF12722.7 GAN02506.1 - 9.7 4.2 7.2 12 3.9 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4203 PF13886.6 GAN02507.1 - 7.6e-12 45.3 13.3 7.6e-12 45.3 13.3 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4203) DUF962 PF06127.11 GAN02507.1 - 0.036 14.2 0.4 0.27 11.3 0.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Peptidase_M48_N PF16491.5 GAN02507.1 - 0.11 12.4 8.7 0.72 9.7 1.1 2.4 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices DUF2755 PF10954.8 GAN02507.1 - 0.13 12.2 0.3 0.13 12.2 0.3 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2755) DUF4131 PF13567.6 GAN02507.1 - 0.15 11.7 8.0 0.13 11.9 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 GAN02507.1 - 1.5 8.5 15.1 0.044 13.5 6.0 2.3 1 1 1 2 2 2 0 Tetraspanin family DUF2157 PF09925.9 GAN02507.1 - 1.5 8.6 10.7 17 5.2 10.7 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) GPI-anchored PF10342.9 GAN02509.1 - 2.9e-10 40.8 2.2 2.9e-10 40.8 2.2 2.2 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peripla_BP_3 PF13377.6 GAN02509.1 - 0.091 13.1 2.4 0.12 12.7 2.4 1.2 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Ecl1 PF12855.7 GAN02510.1 - 5.3e-14 53.8 15.9 6.6e-14 53.4 15.9 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 GAN02510.1 - 0.011 15.8 2.8 0.021 14.9 2.8 1.4 1 0 0 1 1 1 0 MYND finger VATC PF18716.1 GAN02510.1 - 0.17 11.8 4.1 0.33 10.8 4.1 1.5 1 0 0 1 1 1 0 Vms1-associating treble clef domain Ribosomal_L2 PF00181.23 GAN02511.1 - 1.3e-12 47.5 0.1 1.6e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L18_c PF14204.6 GAN02512.1 - 6.5e-22 78.3 4.8 7.9e-22 78.0 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DJ-1_PfpI PF01965.24 GAN02513.1 - 2.1e-44 151.2 0.9 2.4e-44 151.1 0.9 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 GAN02513.1 - 0.00041 20.0 0.9 0.0008 19.1 0.9 1.5 1 1 0 1 1 1 1 C-terminal domain found in long catalases ThiJ_like PF17124.5 GAN02513.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 GAN02513.1 - 0.0075 16.1 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAN02513.1 - 0.0092 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 GAN02513.1 - 0.021 14.6 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Amidohydro_3 PF07969.11 GAN02515.1 - 1.2e-18 67.8 0.8 1e-12 48.3 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 GAN02515.1 - 1.3e-14 54.3 0.1 1.5e-11 44.3 0.0 3.4 4 0 0 4 4 4 2 Amidohydrolase family PUA_3 PF17785.1 GAN02515.1 - 0.15 11.9 0.2 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 PUA-like domain Pan3_PK PF18101.1 GAN02516.1 - 1.8e-61 206.2 0.2 2.8e-61 205.5 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 GAN02516.1 - 8e-07 28.7 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02516.1 - 0.0032 16.8 0.0 0.018 14.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 GAN02516.1 - 1.7 8.5 15.9 0.49 10.3 12.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 GAN02517.1 - 0.00027 20.7 0.0 0.25 11.2 0.0 3.4 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2119 PF09892.9 GAN02517.1 - 0.11 11.8 0.3 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Ribosomal_L28e PF01778.17 GAN02518.1 - 3.9e-33 114.6 5.5 5e-33 114.3 5.5 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF3067 PF11267.8 GAN02519.1 - 0.0071 16.9 0.4 0.0092 16.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) DUF16 PF01519.16 GAN02519.1 - 0.057 13.9 0.9 0.08 13.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Histidinol_dh PF00815.20 GAN02520.1 - 1.1e-162 541.7 1.3 1.1e-162 541.7 1.3 1.5 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 GAN02520.1 - 8.1e-24 83.3 0.1 2.2e-23 81.9 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GAN02520.1 - 6.5e-17 61.8 0.2 2.2e-16 60.1 0.2 2.0 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 GAN02520.1 - 0.049 13.8 1.9 0.071 13.3 0.4 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 GAN02520.1 - 0.16 12.2 0.6 0.41 10.9 0.6 1.7 1 0 0 1 1 1 0 MazG-like family HEPN_AbiA_CTD PF18732.1 GAN02521.1 - 0.16 11.9 0.9 0.28 11.1 0.7 1.5 1 1 0 1 1 1 0 HEPN like, Abia C-terminal domain Tau95 PF09734.9 GAN02521.1 - 0.4 11.5 4.0 0.18 12.6 0.4 1.9 1 1 1 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TLD PF07534.16 GAN02522.1 - 1.4e-34 119.3 0.7 2.4e-34 118.5 0.7 1.3 1 0 0 1 1 1 1 TLD B3_4 PF03483.17 GAN02522.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 2 0 0 2 2 2 0 B3/4 domain WD40 PF00400.32 GAN02523.1 - 6.3e-22 77.5 15.6 0.0014 19.4 0.1 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02523.1 - 2e-11 44.0 0.6 0.18 12.1 0.0 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain zf-P11 PF03854.14 GAN02523.1 - 0.0012 18.5 2.4 0.0012 18.5 2.4 2.3 2 0 0 2 2 2 1 P-11 zinc finger zf-C3HC4_3 PF13920.6 GAN02523.1 - 0.0016 18.2 0.4 0.0048 16.7 0.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40_like PF17005.5 GAN02523.1 - 0.0038 16.6 0.0 0.064 12.6 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain Prok-RING_4 PF14447.6 GAN02523.1 - 0.011 15.6 1.2 0.026 14.4 1.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN02523.1 - 0.021 15.2 3.2 0.088 13.2 3.2 2.1 1 0 0 1 1 1 0 Ring finger domain Tube PF17212.3 GAN02523.1 - 0.061 13.4 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Tail tubular protein Nnf1 PF03980.14 GAN02523.1 - 2.1 8.7 8.3 0.87 10.0 4.8 2.2 2 0 0 2 2 2 0 Nnf1 zf-RING_5 PF14634.6 GAN02523.1 - 9 6.3 7.7 0.97 9.4 1.3 2.7 3 0 0 3 3 3 0 zinc-RING finger domain UPF0016 PF01169.19 GAN02524.1 - 2.2e-42 143.2 19.3 3.6e-21 75.3 4.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 GAN02524.1 - 0.0001 22.0 5.9 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Mntp PF02659.15 GAN02524.1 - 0.00022 21.0 5.2 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 1 Putative manganese efflux pump OFeT_1 PF16955.5 GAN02524.1 - 0.001 18.8 0.2 0.001 18.8 0.2 1.7 2 0 0 2 2 2 1 Ferrous iron uptake permease, iron-lead transporter DUF3341 PF11821.8 GAN02524.1 - 1.9 8.1 6.4 0.86 9.2 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Muskelin_N PF06588.11 GAN02525.1 - 5.6e-67 225.5 0.9 4.8e-35 121.3 0.0 2.3 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_6 PF13964.6 GAN02525.1 - 9.9e-23 79.6 3.4 1.4e-06 28.4 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 GAN02525.1 - 1.7e-21 76.0 0.9 3.4e-09 36.8 0.1 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN02525.1 - 4e-20 71.1 7.9 7e-08 31.9 0.1 5.6 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAN02525.1 - 2.4e-18 65.9 10.2 3.3e-05 23.8 0.7 7.0 6 2 1 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN02525.1 - 1.1e-17 63.6 2.2 0.00021 21.2 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAN02525.1 - 5.4e-15 54.7 3.1 2.7e-06 27.1 0.6 6.3 6 0 0 6 6 6 3 Kelch motif F5_F8_type_C PF00754.25 GAN02525.1 - 0.0055 16.8 0.0 0.023 14.8 0.0 2.1 1 1 0 1 1 1 1 F5/8 type C domain Zn_clus PF00172.18 GAN02526.1 - 5.8e-11 42.3 10.7 1.2e-10 41.3 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC53 PF10152.9 GAN02526.1 - 0.039 14.4 2.2 0.059 13.8 2.2 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PX PF00787.24 GAN02526.1 - 0.21 11.6 2.2 0.31 11.0 0.0 2.2 2 1 0 2 2 2 0 PX domain Mito_fiss_reg PF05308.11 GAN02526.1 - 0.55 10.3 18.5 10 6.1 18.5 2.1 1 1 0 1 1 1 0 Mitochondrial fission regulator Aminotran_5 PF00266.19 GAN02527.1 - 3.1e-13 49.4 0.0 4.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF2011 PF09428.10 GAN02528.1 - 1.3 9.3 5.5 1.4 9.2 0.6 2.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Prefoldin_2 PF01920.20 GAN02529.1 - 1.2e-20 73.4 15.0 1.7e-20 73.0 15.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DMPK_coil PF08826.10 GAN02529.1 - 0.00074 19.6 7.5 0.00074 19.6 7.5 2.2 2 0 0 2 2 2 1 DMPK coiled coil domain like DUF3727 PF12527.8 GAN02529.1 - 0.0056 16.9 1.2 0.0095 16.1 1.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3727) SpecificRecomb PF10136.9 GAN02529.1 - 0.19 10.0 4.6 0.2 10.0 4.6 1.0 1 0 0 1 1 1 0 Site-specific recombinase FlaC_arch PF05377.11 GAN02529.1 - 0.93 9.9 13.2 2.8 8.4 1.5 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 GAN02529.1 - 0.97 9.4 12.5 4.2 7.3 12.5 1.8 1 1 0 1 1 1 0 Prefoldin subunit Spc24 PF08286.11 GAN02529.1 - 0.99 9.7 15.1 1.7 8.9 3.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 GAN02529.1 - 1.3 9.5 8.1 8.6 6.9 0.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MRPL52 PF18699.1 GAN02529.1 - 1.4 9.1 7.0 0.45 10.7 0.7 2.2 2 0 0 2 2 2 0 Mitoribosomal protein mL52 MCU PF04678.13 GAN02529.1 - 9.2 6.3 7.6 16 5.5 7.6 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter AAA_lid_9 PF17871.1 GAN02529.1 - 9.4 6.2 10.6 14 5.7 1.8 2.1 2 0 0 2 2 2 0 AAA lid domain YabA PF06156.13 GAN02529.1 - 9.8 6.9 11.6 3.7e+02 1.8 11.6 2.2 1 1 0 1 1 1 0 Initiation control protein YabA IF4E PF01652.18 GAN02530.1 - 4.1e-37 127.4 1.3 5.8e-37 126.9 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Oxysterol_BP PF01237.18 GAN02531.1 - 8.7e-82 274.9 2.6 3e-80 269.8 2.6 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein ADH_N PF08240.12 GAN02532.1 - 5.7e-21 74.5 4.4 5.7e-21 74.5 4.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN02532.1 - 1.1e-15 57.8 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN02532.1 - 8.9e-05 23.5 0.0 0.00013 23.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAN02532.1 - 0.00039 19.8 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAN02532.1 - 0.022 14.0 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_1 PF00076.22 GAN02533.1 - 8.7e-36 121.6 0.0 5e-15 55.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN02533.1 - 1.5e-06 27.9 0.1 0.00026 20.8 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 GAN02533.1 - 1.9e-06 27.5 0.1 0.094 12.3 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN02533.1 - 9e-05 22.4 0.0 0.47 10.5 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 GAN02533.1 - 0.0003 20.8 0.1 1.4 9.0 0.1 3.1 2 1 1 3 3 3 2 Limkain b1 RRM_3 PF08777.11 GAN02533.1 - 0.00054 20.0 0.0 0.28 11.3 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif SET_assoc PF11767.8 GAN02533.1 - 0.0075 15.9 0.2 4 7.1 0.0 2.8 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated RSD-2 PF07547.13 GAN02533.1 - 0.03 14.8 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 RSD-2 N-terminal domain LptC PF06835.13 GAN02533.1 - 0.039 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related RNA_bind PF08675.11 GAN02533.1 - 0.086 12.9 0.1 12 6.1 0.0 3.1 2 1 1 3 3 3 0 RNA binding domain Zn_clus PF00172.18 GAN02534.1 - 0.0013 18.8 11.5 0.0026 17.8 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rib_5-P_isom_A PF06026.14 GAN02535.1 - 1.4e-62 210.4 0.0 1.7e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GAN02535.1 - 0.012 15.6 0.1 0.85 9.5 0.0 2.2 1 1 1 2 2 2 0 DeoR C terminal sensor domain Sugar-bind PF04198.13 GAN02535.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Linker_histone PF00538.19 GAN02536.1 - 2.1e-26 92.0 0.4 2.1e-26 92.0 0.4 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family SLC12 PF03522.15 GAN02536.1 - 0.15 11.0 7.7 0.22 10.5 7.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PH_9 PF15410.6 GAN02537.1 - 2e-09 37.8 0.1 7.4e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAN02537.1 - 1.7e-06 28.5 0.0 5.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 PH domain SAM_1 PF00536.30 GAN02537.1 - 4.3e-05 23.9 0.0 9.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAN02537.1 - 0.00099 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Formyl_trans_C PF02911.18 GAN02537.1 - 0.018 15.3 0.0 0.3 11.4 0.0 2.3 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain Cation_efflux PF01545.21 GAN02538.1 - 1.3e-26 93.5 14.7 1.8e-26 93.1 14.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAN02538.1 - 2.3e-11 43.7 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MIG-14_Wnt-bd PF06664.12 GAN02538.1 - 0.014 14.7 4.8 0.02 14.1 4.8 1.3 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion F-box PF00646.33 GAN02539.1 - 0.0061 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN02539.1 - 0.0069 16.3 1.4 0.011 15.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like Fanconi_A PF03511.14 GAN02539.1 - 0.3 11.1 1.7 11 6.0 0.1 2.6 2 0 0 2 2 2 0 Fanconi anaemia group A protein Utp13 PF08625.11 GAN02539.1 - 0.45 10.4 4.1 2 8.3 0.6 2.9 2 1 1 3 3 3 0 Utp13 specific WD40 associated domain AhpC-TSA PF00578.21 GAN02540.1 - 7.5e-28 96.9 0.0 9.3e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAN02540.1 - 1.7e-11 44.0 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAN02540.1 - 6.1e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin FKBP_C PF00254.28 GAN02542.1 - 2.1e-31 108.1 0.0 6.9e-31 106.4 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyclin PF08613.11 GAN02542.1 - 8e-06 26.3 0.1 0.11 12.9 0.0 2.5 3 0 0 3 3 3 2 Cyclin Cyclin_N PF00134.23 GAN02542.1 - 1.4e-05 24.8 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sugar_tr PF00083.24 GAN02543.1 - 8.7e-104 347.9 21.8 1.2e-103 347.4 21.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN02543.1 - 3.6e-29 101.8 25.7 1.5e-25 89.9 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 GAN02543.1 - 0.0011 17.9 7.6 0.0015 17.6 1.3 2.3 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM OATP PF03137.20 GAN02543.1 - 0.016 13.5 14.3 0.19 10.0 0.8 3.7 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_S21 PF01165.20 GAN02543.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 Abhydrolase_9_N PF15420.6 GAN02543.1 - 0.3 11.0 3.4 0.6 10.1 2.9 1.8 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus ATP-cone PF03477.16 GAN02544.1 - 0.0087 16.6 0.6 0.78 10.4 0.2 2.1 1 1 1 2 2 2 2 ATP cone domain dCache_2 PF08269.11 GAN02544.1 - 0.026 13.7 0.9 0.037 13.2 0.9 1.2 1 0 0 1 1 1 0 Cache domain MIR PF02815.19 GAN02546.1 - 1e-17 64.6 0.7 5.7e-14 52.4 0.2 2.6 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 GAN02546.1 - 6.6e-05 22.2 0.0 0.00026 20.2 0.0 1.8 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.6 GAN02546.1 - 0.052 14.3 0.2 4.9 8.0 0.1 2.8 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like HLH PF00010.26 GAN02547.1 - 3.6e-17 62.1 0.3 3.6e-17 62.1 0.3 3.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain RTX_C PF08339.10 GAN02547.1 - 0.078 13.0 0.6 1 9.4 0.1 2.7 2 0 0 2 2 2 0 RTX C-terminal domain MerE PF05052.12 GAN02547.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 MerE protein DUF3886 PF13025.6 GAN02547.1 - 0.34 11.1 8.3 1.3 9.2 8.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) bZIP_2 PF07716.15 GAN02549.1 - 1.1e-13 51.0 9.1 1.1e-13 51.0 9.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN02549.1 - 2.7e-13 49.8 12.2 2.7e-13 49.8 12.2 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAN02549.1 - 1.1e-05 25.8 7.6 2.9e-05 24.5 7.6 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor TMCO5 PF14992.6 GAN02549.1 - 0.0005 19.7 7.0 0.00092 18.9 7.0 1.4 1 0 0 1 1 1 1 TMCO5 family CCD48 PF15799.5 GAN02549.1 - 0.013 13.9 1.5 0.018 13.4 1.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Herpes_BLRF2 PF05812.12 GAN02549.1 - 0.022 14.9 5.0 0.06 13.5 1.6 2.9 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein HALZ PF02183.18 GAN02549.1 - 0.025 14.8 3.1 3.5 7.9 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.18 GAN02549.1 - 0.029 14.7 0.9 0.029 14.7 0.9 2.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Glyco_hydro_3_C PF01915.22 GAN02549.1 - 0.047 13.6 2.0 0.038 13.9 0.8 1.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain HAUS6_N PF14661.6 GAN02549.1 - 0.071 12.7 5.8 0.11 12.1 5.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FlaC_arch PF05377.11 GAN02549.1 - 0.19 12.2 4.0 0.22 12.0 1.6 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4337 PF14235.6 GAN02549.1 - 3.3 7.8 7.7 1 9.5 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) O-FucT PF10250.9 GAN02550.1 - 1.9e-14 54.1 0.2 2.9e-12 46.9 0.2 3.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4331 PF14224.6 GAN02550.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) HLH PF00010.26 GAN02551.1 - 1.8e-10 40.6 0.4 1.8e-10 40.6 0.4 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 GAN02552.1 - 2.6e-13 50.2 2.3 0.032 15.1 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02552.1 - 3.5e-05 24.0 0.1 1.5 9.2 0.0 4.8 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Herpes_Helicase PF02689.14 GAN02553.1 - 3e-07 28.8 0.0 3.1e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Helicase ABC_tran PF00005.27 GAN02555.1 - 9.3e-45 152.5 2.9 2e-23 83.4 0.0 4.4 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAN02555.1 - 1.5e-15 57.8 3.3 0.0026 17.6 0.0 4.6 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAN02555.1 - 2.3e-10 40.6 0.0 0.00068 19.6 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 GAN02555.1 - 3.3e-10 39.8 7.4 0.0065 15.9 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAN02555.1 - 1.6e-09 37.9 2.0 0.00089 19.1 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain ABC_tran_Xtn PF12848.7 GAN02555.1 - 2.4e-08 33.9 8.3 2.4e-08 33.9 8.3 2.6 3 0 0 3 3 2 1 ABC transporter MMR_HSR1 PF01926.23 GAN02555.1 - 4.3e-06 26.8 0.1 0.0068 16.5 0.0 3.3 3 0 0 3 3 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 GAN02555.1 - 4.6e-06 27.0 0.0 0.17 12.3 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_29 PF13555.6 GAN02555.1 - 8.9e-06 25.4 0.0 0.025 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN02555.1 - 1.2e-05 25.6 0.2 0.062 13.6 0.3 3.4 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.9 GAN02555.1 - 1.3e-05 24.6 1.1 0.0078 15.4 0.0 3.4 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 GAN02555.1 - 3.5e-05 24.3 0.0 0.18 12.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 GAN02555.1 - 4.3e-05 24.0 0.0 0.43 11.0 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAN02555.1 - 6e-05 23.0 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 GAN02555.1 - 0.00023 21.4 0.0 0.003 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAN02555.1 - 0.00091 19.0 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GAN02555.1 - 0.0028 16.9 0.2 1.1 8.4 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.6 GAN02555.1 - 0.0041 17.1 2.2 6.1 6.9 0.0 4.1 5 0 0 5 5 3 0 AAA domain AAA_5 PF07728.14 GAN02555.1 - 0.0048 16.9 0.0 2 8.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 GAN02555.1 - 0.0071 15.9 4.6 0.067 12.7 0.1 3.7 3 1 1 4 4 4 1 Ferrous iron transport protein B ATPase_2 PF01637.18 GAN02555.1 - 0.0071 16.3 4.0 1.5 8.7 0.0 3.9 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 GAN02555.1 - 0.0072 15.9 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 GAN02555.1 - 0.0092 15.9 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Roc PF08477.13 GAN02555.1 - 0.0096 16.1 0.2 5.5 7.2 0.0 3.1 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN02555.1 - 0.012 15.0 1.9 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_33 PF13671.6 GAN02555.1 - 0.013 15.7 3.0 1.1 9.5 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_23 PF13476.6 GAN02555.1 - 0.02 15.4 0.2 0.02 15.4 0.2 4.0 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 GAN02555.1 - 0.021 14.4 0.1 7.7 6.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAN02555.1 - 0.024 15.2 0.0 2 8.9 0.0 3.4 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAN02555.1 - 0.085 12.6 0.1 18 5.0 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 GAN02555.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.4 3 1 1 4 4 4 0 Dynamin family PduV-EutP PF10662.9 GAN02555.1 - 0.12 12.1 0.4 1.3 8.7 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane PF01061.24 GAN02556.1 - 1.9e-82 275.8 54.7 2.7e-46 157.7 17.0 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAN02556.1 - 1.7e-37 129.0 0.0 2.6e-20 73.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAN02556.1 - 1.5e-34 117.7 4.1 1.7e-26 91.9 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAN02556.1 - 1.6e-14 54.3 0.1 4.1e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAN02556.1 - 1.4e-07 31.0 43.6 0.00018 20.7 19.9 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 GAN02556.1 - 3.2e-05 24.4 0.0 0.032 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAN02556.1 - 0.00022 21.2 0.1 0.0038 17.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 GAN02556.1 - 0.00059 20.4 0.1 0.056 14.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 GAN02556.1 - 0.00072 19.4 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAN02556.1 - 0.003 17.3 0.3 0.062 13.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAN02556.1 - 0.0063 16.6 0.2 5.3 7.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 GAN02556.1 - 0.0094 16.2 0.0 1.8 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAN02556.1 - 0.032 13.8 0.5 0.095 12.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain Pax2_C PF12403.8 GAN02556.1 - 0.042 13.9 0.1 0.098 12.7 0.1 1.5 1 0 0 1 1 1 0 Paired-box protein 2 C terminal AAA_30 PF13604.6 GAN02556.1 - 0.046 13.4 0.4 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAN02556.1 - 0.14 12.3 0.0 0.82 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAN02556.1 - 0.17 12.3 0.6 32 4.9 0.2 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAN02556.1 - 0.18 12.1 1.0 0.7 10.1 0.2 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAN02556.1 - 0.2 11.2 1.0 2.4 7.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAN02556.1 - 0.25 11.3 0.5 3.3 7.6 0.2 2.3 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 GAN02556.1 - 0.26 11.0 0.5 9.9 5.9 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AMP-binding PF00501.28 GAN02557.1 - 1.1e-94 317.5 0.0 1.4e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN02557.1 - 1.1e-11 45.6 0.0 2.4e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 GAN02558.1 - 7.1e-97 324.7 0.0 9.3e-97 324.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN02558.1 - 9.1e-14 52.2 0.0 2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FUSC_2 PF13515.6 GAN02559.1 - 5.4e-14 52.4 14.7 5.4e-14 52.4 14.7 3.6 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 GAN02559.1 - 1.8e-13 50.9 0.0 3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 GAN02559.1 - 4e-10 39.3 12.9 1.8e-07 30.6 0.8 2.3 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 GAN02559.1 - 2.9e-05 22.8 4.2 2.9e-05 22.8 4.2 2.8 2 1 1 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 GAN02559.1 - 0.0001 21.3 3.9 0.0001 21.3 3.9 3.1 2 1 1 3 3 3 1 Aluminium activated malate transporter DUF4405 PF14358.6 GAN02559.1 - 0.22 12.1 0.0 0.22 12.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) E1-E2_ATPase PF00122.20 GAN02560.1 - 2.8e-50 170.3 3.0 1.8e-49 167.7 0.0 3.3 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 GAN02560.1 - 5.8e-15 56.1 0.2 2.4e-14 54.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN02560.1 - 4.1e-12 45.6 0.0 1.1e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN02560.1 - 6.8e-05 22.7 0.2 6.8e-05 22.7 0.2 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN02560.1 - 0.015 15.4 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) SWIRM PF04433.17 GAN02561.1 - 7.5e-21 74.3 0.0 5.7e-20 71.5 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 GAN02561.1 - 5.2e-13 49.0 1.2 1.7e-12 47.3 1.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN02561.1 - 3.5e-06 27.2 0.1 3.5e-06 27.2 0.1 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain SLIDE PF09111.10 GAN02561.1 - 0.0017 18.4 0.1 0.0084 16.1 0.0 2.2 2 0 0 2 2 2 1 SLIDE Auxin_inducible PF02519.14 GAN02561.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Auxin responsive protein NDT80_PhoG PF05224.12 GAN02562.1 - 1.6e-37 129.6 1.0 3.2e-37 128.5 0.0 2.1 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DAHP_synth_2 PF01474.16 GAN02563.1 - 3.4e-209 694.8 0.0 3.8e-209 694.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family TMEM234 PF10639.9 GAN02564.1 - 3.3e-33 114.2 0.9 3.3e-19 69.0 0.1 2.5 2 0 0 2 2 2 2 Putative transmembrane family 234 Methyltransf_16 PF10294.9 GAN02564.1 - 7.9e-29 100.6 0.1 1.5e-28 99.7 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Lipase_GDSL PF00657.22 GAN02564.1 - 1.4e-07 31.7 0.1 3e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN02564.1 - 6.2e-06 26.7 0.1 5.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Cons_hypoth95 PF03602.15 GAN02564.1 - 0.029 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ald_deCOase PF11266.8 GAN02564.1 - 0.07 12.8 0.4 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Long-chain fatty aldehyde decarbonylase AA_kinase PF00696.28 GAN02567.1 - 1.4e-29 103.4 0.0 1.8e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family Phage_CP76 PF06892.11 GAN02567.1 - 0.24 10.9 2.7 0.44 10.1 1.4 2.1 2 1 0 2 2 2 0 Phage regulatory protein CII (CP76) TPR_2 PF07719.17 GAN02568.1 - 3.5e-08 32.9 8.7 0.039 14.1 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN02568.1 - 1.8e-06 28.3 0.7 0.52 11.3 0.1 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAN02568.1 - 1.1e-05 25.9 0.2 0.25 12.0 0.1 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN02568.1 - 8.4e-05 22.2 7.7 0.11 12.4 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN02568.1 - 0.00028 20.5 0.2 0.068 12.9 0.0 2.9 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 GAN02568.1 - 0.00029 21.1 0.8 0.25 11.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN02568.1 - 0.0018 18.8 11.8 0.34 11.5 0.1 4.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN02568.1 - 0.21 11.7 1.9 3.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PerC PF06069.11 GAN02569.1 - 0.34 11.2 3.1 0.64 10.3 0.2 2.1 2 0 0 2 2 2 0 PerC transcriptional activator GAGE PF05831.11 GAN02569.1 - 0.93 10.1 10.3 0.28 11.7 3.8 2.1 1 1 1 2 2 2 0 GAGE protein WD40 PF00400.32 GAN02571.1 - 4.5e-16 58.9 10.9 0.00014 22.5 1.0 8.6 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02571.1 - 7.9e-10 38.9 5.0 0.15 12.3 0.0 6.2 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN02571.1 - 0.00045 20.2 0.5 0.92 9.4 0.0 3.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF2959 PF11172.8 GAN02571.1 - 0.018 15.2 2.6 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) BBS2_Mid PF14783.6 GAN02571.1 - 0.045 13.8 1.1 4.3 7.4 0.0 3.6 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region LVIVD PF08309.11 GAN02571.1 - 1.2 8.5 4.2 3.2 7.1 0.0 3.2 3 0 0 3 3 3 0 LVIVD repeat KH_6 PF15985.5 GAN02572.1 - 4.7e-18 65.3 0.0 9.7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 GAN02572.1 - 2e-11 43.7 0.0 4.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain YdfA_immunity PF12127.8 GAN02572.1 - 0.0011 18.1 1.3 0.067 12.2 0.1 2.1 2 0 0 2 2 2 2 SigmaW regulon antibacterial ECR1_N PF14382.6 GAN02572.1 - 0.024 14.4 0.8 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Cys_Met_Meta_PP PF01053.20 GAN02573.1 - 5.2e-36 124.0 0.0 7.2e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAN02573.1 - 0.0065 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II GCR1_C PF12550.8 GAN02573.1 - 0.15 12.4 0.9 7.9 6.9 0.2 2.9 3 0 0 3 3 3 0 Transcriptional activator of glycolytic enzymes Sugar_tr PF00083.24 GAN02574.1 - 4.2e-96 322.6 27.4 1.1e-94 317.9 27.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN02574.1 - 5.4e-33 114.4 26.6 8.4e-32 110.5 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG_C PF09333.11 GAN02575.1 - 0.13 12.7 0.1 0.53 10.7 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain RNA_pol_I_TF PF04090.12 GAN02576.1 - 0.0038 16.8 0.1 0.026 14.0 0.0 2.3 1 1 1 2 2 2 1 RNA polymerase I specific initiation factor PPR_2 PF13041.6 GAN02576.1 - 0.034 14.3 0.2 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 PPR repeat family SRA PF18491.1 GAN02576.1 - 1.2 9.2 6.4 0.26 11.4 0.4 2.7 2 1 1 3 3 3 0 SET and RING associated domain MFS_1 PF07690.16 GAN02577.1 - 2.9e-35 121.8 29.6 2.9e-35 121.8 29.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Transgly_assoc PF04226.13 GAN02577.1 - 0.013 15.7 0.1 0.013 15.7 0.1 3.1 3 0 0 3 3 3 0 Transglycosylase associated protein DUF5408 PF17402.2 GAN02577.1 - 0.49 10.3 2.1 0.66 9.9 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5408) Man-6-P_recep PF02157.15 GAN02577.1 - 2.3 7.2 3.7 0.81 8.7 0.6 1.8 2 0 0 2 2 2 0 Mannose-6-phosphate receptor DUF1764 PF08576.10 GAN02578.1 - 1.7e-17 64.2 3.0 1.7e-17 64.2 3.0 3.3 1 1 2 3 3 3 2 Eukaryotic protein of unknown function (DUF1764) CDC27 PF09507.10 GAN02578.1 - 0.67 9.3 26.7 0.82 9.0 26.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 GAN02578.1 - 0.79 7.9 21.0 0.88 7.7 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family RIFIN PF02009.16 GAN02578.1 - 1.4 8.7 13.6 1.7 8.4 13.6 1.0 1 0 0 1 1 1 0 Rifin zf-UBR PF02207.20 GAN02579.1 - 1.3e-19 70.1 12.8 1.3e-19 70.1 12.8 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAN02579.1 - 7.5e-10 38.5 1.3 2.8e-09 36.6 0.1 2.4 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS ECH_1 PF00378.20 GAN02580.1 - 1.1e-46 159.1 0.0 1.7e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN02580.1 - 4.5e-28 98.7 0.0 7.1e-25 88.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase UTP15_C PF09384.10 GAN02581.1 - 1.2e-47 161.3 1.3 2e-47 160.6 1.3 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 GAN02581.1 - 1.1e-25 89.3 4.7 1.6e-06 28.7 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02581.1 - 7.2e-11 42.3 0.1 0.00071 19.8 0.0 5.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.27 GAN02585.1 - 3.2e-35 121.5 5.0 2.4e-33 115.3 5.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAN02585.1 - 3e-31 107.7 3.3 9.1e-31 106.1 3.3 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 GAN02585.1 - 8e-10 39.0 1.9 1.5e-05 25.3 0.0 3.9 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAN02585.1 - 2.1e-09 37.5 0.3 7.2e-09 35.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 GAN02585.1 - 0.00019 20.9 0.0 0.0004 19.9 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 GAN02585.1 - 0.00033 20.2 0.1 0.0012 18.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAN02585.1 - 0.00087 19.2 1.0 0.012 15.5 0.0 2.6 1 1 1 2 2 2 1 RsgA GTPase Ras PF00071.22 GAN02585.1 - 0.0022 17.6 0.0 0.0067 16.0 0.0 1.8 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN02585.1 - 0.0043 17.3 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase T6SS_VipA PF05591.12 GAN02585.1 - 0.0074 16.1 0.1 0.041 13.7 0.0 2.3 2 0 0 2 2 2 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 GTP_EFTU_D4 PF14578.6 GAN02585.1 - 0.015 15.2 7.1 0.067 13.1 0.1 3.2 3 0 0 3 3 3 0 Elongation factor Tu domain 4 SRPRB PF09439.10 GAN02585.1 - 0.068 12.6 0.2 0.22 11.0 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 GAN02585.1 - 0.96 9.5 4.3 1.4 8.9 0.0 3.1 2 2 1 3 3 3 0 Dynamin family DUF1682 PF07946.14 GAN02586.1 - 1.3 8.1 17.0 2.3 7.3 17.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) V_ATPase_I PF01496.19 GAN02586.1 - 2 6.2 8.3 2.8 5.7 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 GAN02586.1 - 2.4 7.9 11.9 3.4 7.4 11.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMPIT PF07851.13 GAN02586.1 - 5.1 6.2 6.4 6.9 5.8 6.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Presenilin PF01080.17 GAN02586.1 - 9.3 4.9 7.7 11 4.6 7.7 1.1 1 0 0 1 1 1 0 Presenilin RNase_P_p30 PF01876.16 GAN02587.1 - 2.6e-44 151.3 0.3 3.4e-44 150.9 0.3 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Tom37 PF10568.9 GAN02588.1 - 5.6e-23 81.6 0.5 1.7e-22 80.1 0.2 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 GAN02588.1 - 8.4e-20 71.4 0.3 1.1e-18 67.8 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAN02588.1 - 7.9e-17 60.8 0.2 3.9e-16 58.6 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN02588.1 - 2.8e-06 27.2 0.0 1.5e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NTP_transf_8 PF12281.8 GAN02588.1 - 0.11 12.5 0.5 0.32 11.0 0.1 1.8 2 0 0 2 2 2 0 Nucleotidyltransferase FUSC_2 PF13515.6 GAN02589.1 - 6.6e-15 55.4 14.9 6.6e-15 55.4 14.9 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 GAN02589.1 - 5.9e-14 52.5 0.0 1.6e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 GAN02589.1 - 1.3e-12 47.6 9.3 1.3e-06 27.8 0.2 3.4 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 GAN02589.1 - 3.2e-12 46.0 2.0 3.2e-12 46.0 2.0 4.8 3 1 2 5 5 5 2 Aluminium activated malate transporter FUSC PF04632.12 GAN02589.1 - 1.4e-11 43.8 18.2 2.6e-09 36.2 17.3 2.8 3 0 0 3 3 3 2 Fusaric acid resistance protein family ArAE_1 PF06081.11 GAN02589.1 - 0.00068 19.8 5.6 0.00068 19.8 5.6 3.1 2 1 0 3 3 3 1 Aromatic acid exporter family member 1 FUSC-like PF12805.7 GAN02589.1 - 0.037 13.1 4.4 0.019 14.0 0.8 2.4 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS dCMP_cyt_deam_2 PF08211.12 GAN02589.1 - 0.084 13.1 1.8 8.3 6.6 0.2 2.7 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region ox_reductase_C PF08635.10 GAN02589.1 - 0.094 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain DUF4363 PF14276.6 GAN02589.1 - 1.2 9.3 5.5 2.3 8.3 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) DUF948 PF06103.11 GAN02589.1 - 1.5 9.1 3.7 5.1 7.4 0.2 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ribosomal_L27A PF00828.19 GAN02590.1 - 2e-08 35.0 0.1 3.6e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SRX PF09201.10 GAN02590.1 - 0.11 12.4 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit ubiquitin PF00240.23 GAN02591.1 - 2e-66 219.7 6.4 1.2e-32 111.5 0.6 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 GAN02591.1 - 3.6e-29 100.4 6.5 5.7e-14 51.7 0.7 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 GAN02591.1 - 5.5e-12 45.7 8.2 8.6e-12 45.0 8.2 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 GAN02591.1 - 9.1e-11 42.1 2.2 0.0007 20.0 0.2 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 GAN02591.1 - 3.8e-07 30.6 0.2 0.0087 16.6 0.1 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAN02591.1 - 7.1e-07 29.5 1.1 0.046 14.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 GAN02591.1 - 9.2e-07 28.7 0.3 0.054 13.4 0.1 2.3 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAN02591.1 - 1.4e-05 25.1 0.2 0.19 11.9 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 GAN02591.1 - 0.00017 21.5 0.1 0.51 10.2 0.0 2.2 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF3861 PF12977.7 GAN02591.1 - 0.0026 17.9 0.3 3.9 7.7 0.0 2.6 2 0 0 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) Ubiquitin_4 PF18036.1 GAN02591.1 - 0.0035 17.3 8.3 22 5.2 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-like domain ACT_5 PF13710.6 GAN02591.1 - 0.017 14.9 0.7 6.6 6.7 0.1 2.4 2 0 0 2 2 2 0 ACT domain UDP-g_GGTase PF06427.11 GAN02591.1 - 0.072 13.2 0.9 0.77 9.9 0.1 2.6 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 GAN02591.1 - 0.075 13.8 0.0 24 5.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig domain DUF2870 PF11069.8 GAN02591.1 - 0.098 13.1 0.0 19 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF493 PF04359.14 GAN02591.1 - 0.14 12.7 0.0 35 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF493) DUF1940 PF09155.10 GAN02591.1 - 0.15 12.2 0.5 22 5.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) Raf1_HTH PF18579.1 GAN02591.1 - 0.17 11.6 0.1 25 4.7 0.0 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Tash_PEST PF07708.11 GAN02591.1 - 0.46 10.7 9.6 4.7 7.5 1.4 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Plexin_cytopl PF08337.12 GAN02591.1 - 6.2 5.4 5.5 16 4.0 0.4 2.6 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain DUF4221 PF13970.6 GAN02592.1 - 0.071 12.7 0.3 0.095 12.2 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) LmjF365940-deam PF14421.6 GAN02594.1 - 0.036 13.7 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases NDC10_II PF16787.5 GAN02595.1 - 5.4e-06 25.7 0.0 0.00022 20.4 0.0 2.2 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 zf-BED PF02892.15 GAN02596.1 - 0.0062 16.5 0.9 0.015 15.3 0.9 1.6 1 0 0 1 1 1 1 BED zinc finger DUF3439 PF11921.8 GAN02599.1 - 0.25 11.3 18.3 0.84 9.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Cullin PF00888.22 GAN02600.1 - 2e-139 466.1 27.0 2.8e-139 465.5 27.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAN02600.1 - 2e-14 53.4 0.1 8.5e-14 51.3 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Glyco_transf_22 PF03901.17 GAN02601.1 - 4.8e-62 210.5 23.4 6.3e-62 210.1 23.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 GAN02601.1 - 4.3e-05 23.8 11.8 4.3e-05 23.8 11.8 3.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Presenilin PF01080.17 GAN02602.1 - 0.8 8.4 16.5 0.082 11.7 11.1 1.8 2 0 0 2 2 2 0 Presenilin RR_TM4-6 PF06459.12 GAN02602.1 - 5.5 6.7 16.9 0.88 9.3 12.3 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ARID PF01388.21 GAN02603.1 - 2.8e-19 69.6 0.0 6.4e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C2H2_aberr PF17017.5 GAN02603.1 - 0.00014 22.0 3.4 0.00031 20.9 3.4 1.5 1 0 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 GAN02603.1 - 0.013 16.1 5.7 0.45 11.2 0.4 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain RFX_DNA_binding PF02257.15 GAN02603.1 - 0.11 13.1 0.0 0.34 11.6 0.0 1.8 1 0 0 1 1 1 0 RFX DNA-binding domain zf-C2H2 PF00096.26 GAN02603.1 - 0.16 12.5 6.5 4.4 8.0 0.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN02603.1 - 1.6 9.7 6.5 14 6.8 0.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger AFG1_ATPase PF03969.16 GAN02604.1 - 9.4e-107 357.0 6.1 4.1e-101 338.5 3.0 2.9 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 GAN02604.1 - 1.2e-05 25.7 2.0 0.031 14.7 0.0 3.6 3 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 GAN02604.1 - 0.00039 20.7 0.1 0.0033 17.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAN02604.1 - 0.0042 17.1 0.0 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Z1 PF10593.9 GAN02604.1 - 0.033 13.7 1.5 0.056 12.9 0.2 2.0 2 0 0 2 2 2 0 Z1 domain NACHT PF05729.12 GAN02604.1 - 0.038 13.9 0.1 0.47 10.3 0.0 2.6 2 1 0 2 2 2 0 NACHT domain AAA PF00004.29 GAN02604.1 - 0.043 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 GAN02604.1 - 0.16 11.9 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAN02604.1 - 0.57 10.5 2.0 35 4.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain NDT80_PhoG PF05224.12 GAN02605.1 - 7.8e-33 114.2 0.5 7.8e-33 114.2 0.5 3.8 2 2 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Cir_N PF10197.9 GAN02606.1 - 1.8e-09 37.6 3.4 1.8e-09 37.6 3.4 4.9 6 0 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Tubulin_3 PF14881.6 GAN02607.1 - 2.1e-46 157.9 0.1 3.6e-46 157.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 GAN02607.1 - 5.2e-37 126.7 1.9 8.2e-37 126.1 0.2 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 GAN02607.1 - 1.1e-08 35.6 0.5 0.00028 21.2 0.0 2.8 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Sin3_corepress PF08295.12 GAN02607.1 - 0.082 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Sin3 family co-repressor FlxA PF14282.6 GAN02607.1 - 0.092 12.7 1.7 0.17 11.9 1.7 1.4 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 GAN02607.1 - 0.26 11.1 1.8 0.37 10.6 0.7 1.8 2 0 0 2 2 2 0 Septum formation initiator PDCD7 PF16021.5 GAN02608.1 - 8.3e-12 44.8 30.6 3.3e-08 33.0 2.2 2.1 1 1 1 2 2 2 2 Programmed cell death protein 7 Nramp PF01566.18 GAN02608.1 - 0.16 10.9 0.2 0.23 10.4 0.2 1.1 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein CM_2 PF01817.21 GAN02608.1 - 0.52 10.7 7.6 2.8 8.4 1.6 2.6 1 1 1 2 2 2 0 Chorismate mutase type II GATA PF00320.27 GAN02609.1 - 1.1e-14 53.8 2.7 1.1e-14 53.8 2.7 2.2 2 1 1 3 3 3 1 GATA zinc finger ProRS-C_1 PF09180.11 GAN02610.1 - 6e-25 87.2 0.2 1.4e-24 86.1 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 GAN02610.1 - 3.3e-20 72.0 0.0 1.5e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAN02610.1 - 1.5e-17 64.1 0.0 3.1e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 GAN02610.1 - 4e-14 52.8 0.6 9.1e-14 51.6 0.6 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_60s PF00428.19 GAN02610.1 - 0.011 16.3 2.3 0.011 16.3 2.3 3.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein EpmC PF04315.12 GAN02610.1 - 0.042 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Elongation factor P hydroxylase SYS1 PF09801.9 GAN02611.1 - 6.2e-44 149.7 12.9 7.9e-44 149.3 12.9 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network UBA2_C PF16195.5 GAN02611.1 - 0.46 11.2 9.1 0.11 13.2 5.8 1.6 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Plasmodium_Vir PF05795.11 GAN02611.1 - 1.8 7.9 4.4 2.4 7.5 4.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 GAN02611.1 - 4.7 8.2 9.3 2.9 8.9 6.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) TYW3 PF02676.14 GAN02612.1 - 1.4e-60 204.3 0.0 1.2e-59 201.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase TYW3 Ras PF00071.22 GAN02612.1 - 1.1e-47 161.7 0.0 2.2e-47 160.7 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 GAN02612.1 - 1.3e-28 99.6 0.0 4.2e-28 98.0 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN02612.1 - 7.9e-10 38.5 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 GAN02612.1 - 0.0011 19.3 0.3 0.013 15.9 0.0 2.7 2 1 0 2 2 2 1 RNA helicase Gtr1_RagA PF04670.12 GAN02612.1 - 0.0042 16.5 0.1 0.0091 15.4 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region UPF0172 PF03665.13 GAN02612.1 - 0.0075 16.3 0.3 0.012 15.6 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) MMR_HSR1 PF01926.23 GAN02612.1 - 0.031 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 GAN02612.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 GAN02612.1 - 0.054 13.0 0.9 0.092 12.2 0.1 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 GAN02612.1 - 0.064 13.6 0.2 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 GAN02612.1 - 0.083 12.6 0.2 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 GAN02612.1 - 0.16 11.1 2.1 1.7 7.7 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 GAN02612.1 - 0.3 11.0 1.8 12 5.7 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Ribosomal_L40e PF01020.17 GAN02613.1 - 4.2e-20 71.4 9.6 4.2e-20 71.4 9.6 1.5 2 0 0 2 2 2 1 Ribosomal L40e family Zn_Tnp_IS91 PF14319.6 GAN02613.1 - 0.08 13.0 3.0 0.13 12.3 3.0 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain ORC5_C PF14630.6 GAN02614.1 - 3.2e-75 253.3 0.3 4.4e-75 252.8 0.3 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 GAN02614.1 - 2.8e-14 53.8 0.0 8.5e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAN02614.1 - 4.9e-08 33.3 0.0 2.5e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAN02614.1 - 5.5e-06 26.2 0.0 1.2e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAN02614.1 - 2e-05 24.9 0.0 4.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAN02614.1 - 0.00034 20.6 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAN02614.1 - 0.0014 18.6 0.0 0.0041 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAN02614.1 - 0.0021 18.5 0.0 0.005 17.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAN02614.1 - 0.1 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 GAN02614.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF2075 PF09848.9 GAN02614.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) OrfB_IS605 PF01385.19 GAN02614.1 - 0.25 11.6 1.4 0.49 10.6 0.3 1.9 2 0 0 2 2 2 0 Probable transposase zf-MYND PF01753.18 GAN02615.1 - 7.7e-08 32.3 11.9 1.6e-07 31.3 11.9 1.6 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.6 GAN02615.1 - 5.6e-07 29.3 10.5 0.00071 19.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN02615.1 - 6.2e-07 29.0 7.4 3.3e-05 23.5 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN02615.1 - 8e-06 25.9 0.0 0.0012 19.0 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN02615.1 - 0.00013 21.9 7.3 0.022 14.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN02615.1 - 0.0027 18.3 0.0 0.26 12.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN02615.1 - 0.0076 16.5 1.7 1.1 9.6 0.7 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN02615.1 - 0.0078 16.8 0.1 11 7.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN02615.1 - 0.0082 15.8 0.1 0.1 12.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 GAN02615.1 - 0.015 16.1 0.1 4.2 8.5 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat PIH1 PF08190.12 GAN02616.1 - 2.9e-19 69.1 0.0 4.6e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain Pex14_N PF04695.13 GAN02616.1 - 0.05 14.3 0.1 0.12 13.0 0.1 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TAF1D PF15333.6 GAN02618.1 - 0.0047 16.7 0.9 0.0098 15.6 0.9 1.5 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D DUF3140 PF11338.8 GAN02618.1 - 0.0099 16.3 0.2 0.019 15.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Carn_acyltransf PF00755.20 GAN02619.1 - 5.1e-177 590.1 0.0 6.1e-177 589.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase C2 PF00168.30 GAN02620.1 - 6.6e-11 42.4 0.0 1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain WD40 PF00400.32 GAN02621.1 - 5.3e-58 191.6 21.4 5.4e-08 33.4 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02621.1 - 1.3e-16 60.6 3.2 1.6e-05 25.1 0.1 5.6 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN02621.1 - 7.5e-11 41.4 9.1 0.007 15.1 0.0 6.0 2 2 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAN02621.1 - 2.9e-08 32.9 4.7 0.15 10.8 0.2 4.9 2 2 2 5 5 5 3 Nup133 N terminal like Ge1_WD40 PF16529.5 GAN02621.1 - 0.00044 19.3 6.9 0.014 14.4 0.2 3.6 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 GAN02621.1 - 0.023 14.6 0.1 0.062 13.3 0.1 1.7 1 0 0 1 1 1 0 LisH DUF1830 PF08865.11 GAN02621.1 - 0.16 12.0 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1830) DUF3621 PF12285.8 GAN02622.1 - 0.95 9.9 4.4 0.59 10.5 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3621) ECH_2 PF16113.5 GAN02623.1 - 9e-129 429.7 0.0 1.2e-128 429.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAN02623.1 - 2.8e-32 112.0 0.0 6.8e-29 100.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Hydrolase_3 PF08282.12 GAN02624.1 - 0.064 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1211 PF06736.11 GAN02625.1 - 4 7.9 10.5 60 4.2 10.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) RGS PF00615.19 GAN02626.1 - 8e-22 77.7 0.1 2.1e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.21 GAN02626.1 - 1.6e-11 44.1 0.4 3.3e-06 27.1 0.3 3.7 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KI67R PF08065.12 GAN02626.1 - 0.041 14.4 2.1 0.13 12.9 2.1 1.8 1 0 0 1 1 1 0 KI67R (NUC007) repeat CCDC24 PF15669.5 GAN02626.1 - 0.059 13.2 2.2 0.16 11.8 2.2 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF3808 PF10300.9 GAN02628.1 - 1.9e-91 307.2 6.7 4e-91 306.1 6.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Ras PF00071.22 GAN02628.1 - 4.1e-52 176.1 0.0 9.5e-52 174.9 0.0 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN02628.1 - 1.3e-20 73.8 0.0 2.3e-19 69.8 0.0 2.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN02628.1 - 3.9e-07 29.7 0.0 8.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family UMPH-1 PF05822.12 GAN02629.1 - 2.1e-78 263.2 2.9 2.9e-78 262.8 2.9 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 GAN02629.1 - 0.00016 22.2 0.0 0.00029 21.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2538 PF10804.8 GAN02629.1 - 0.017 14.9 1.4 0.035 13.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2538) DUF3335 PF11814.8 GAN02629.1 - 0.091 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family PPR_2 PF13041.6 GAN02630.1 - 3.1e-67 222.6 13.7 7.3e-08 32.5 0.0 17.3 15 4 5 20 20 20 14 PPR repeat family PPR PF01535.20 GAN02630.1 - 1.1e-38 128.8 23.5 0.00056 20.0 0.1 17.8 21 0 0 21 21 21 10 PPR repeat PPR_3 PF13812.6 GAN02630.1 - 4.3e-35 119.6 13.2 1.6e-05 24.9 0.0 12.9 11 1 2 14 14 14 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAN02630.1 - 2.2e-29 100.8 3.1 2.7e-05 23.8 0.0 12.6 12 1 0 12 12 12 6 PPR repeat PPR_long PF17177.4 GAN02630.1 - 3.7e-28 98.3 16.1 5.2e-06 26.0 0.1 8.7 3 2 5 8 8 8 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAN02630.1 - 4.4e-06 27.1 5.2 0.00062 20.2 1.0 4.6 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 GAN02630.1 - 0.0004 20.2 5.6 16 5.4 0.0 6.6 6 1 1 7 7 7 1 Mitochondrial ATPase expression TPR_19 PF14559.6 GAN02630.1 - 0.0016 18.9 13.3 0.69 10.5 0.1 7.7 8 1 0 8 8 8 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAN02630.1 - 0.012 15.6 2.9 14 5.5 0.0 5.1 6 1 1 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 GAN02630.1 - 0.072 13.4 6.6 27 5.1 0.5 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Lipase_3 PF01764.25 GAN02631.1 - 1.5e-18 67.0 0.0 1.3e-17 64.0 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) XPA_N PF01286.18 GAN02631.1 - 0.38 10.8 1.2 1.1 9.4 1.2 1.8 1 0 0 1 1 1 0 XPA protein N-terminal NIF PF03031.18 GAN02632.1 - 8.5e-13 48.4 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.25 GAN02633.1 - 1.5e-41 142.5 0.0 2e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02633.1 - 1.3e-21 77.0 0.0 3.9e-10 39.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 GAN02633.1 - 8.9e-11 42.0 0.2 1.9e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 FHA domain NDT80_PhoG PF05224.12 GAN02634.1 - 2.8e-38 132.0 0.6 8.9e-38 130.4 0.0 2.2 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family SNF2_N PF00176.23 GAN02635.1 - 1e-47 162.6 0.7 2e-46 158.3 0.6 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN02635.1 - 3.2e-14 53.2 0.0 1.7e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN02635.1 - 3.3e-11 43.5 0.0 6.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAN02635.1 - 0.0004 20.1 0.1 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 GAN02635.1 - 0.0045 16.8 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAN02635.1 - 0.036 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RhoGEF PF00621.20 GAN02636.1 - 2.5e-28 99.5 4.6 2.5e-28 99.5 4.6 2.0 2 0 0 2 2 2 1 RhoGEF domain Pyr_redox_2 PF07992.14 GAN02637.1 - 1.1e-28 100.3 0.0 2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN02637.1 - 1.6e-12 47.8 0.1 3.7e-07 30.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 GAN02637.1 - 2.4e-08 34.3 0.5 6.1e-08 33.0 0.5 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pyr_redox_3 PF13738.6 GAN02637.1 - 2.5e-06 27.0 0.3 5.9e-05 22.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN02637.1 - 2.9e-06 27.1 0.1 0.22 11.0 0.0 3.4 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAN02637.1 - 1.4e-05 25.1 0.0 3.6 7.6 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAN02637.1 - 2e-05 24.7 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain RGS-like PF09128.11 GAN02637.1 - 0.0026 17.5 0.2 0.0048 16.6 0.2 1.4 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain ThiF PF00899.21 GAN02637.1 - 0.0027 17.1 0.0 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 ThiF family K_oxygenase PF13434.6 GAN02637.1 - 0.0029 16.8 0.0 0.11 11.6 0.0 2.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 GAN02637.1 - 0.008 15.3 0.0 3 6.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAN02637.1 - 0.025 13.8 0.0 6.5 5.9 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain Spermine_synth PF01564.17 GAN02637.1 - 0.037 13.4 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Spermine/spermidine synthase domain DUF1188 PF06690.11 GAN02637.1 - 0.04 13.5 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Sacchrp_dh_NADP PF03435.18 GAN02637.1 - 0.052 13.8 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAN02637.1 - 0.065 13.5 0.0 7.9 6.8 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 GAN02637.1 - 0.073 11.9 0.1 0.41 9.4 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 GAN02637.1 - 0.12 11.4 2.5 7.1 5.6 0.4 3.3 4 1 0 4 4 4 0 Glucose inhibited division protein A Nop PF01798.18 GAN02638.1 - 1.3e-73 247.3 0.0 1.3e-73 247.3 0.0 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GAN02638.1 - 1.3e-37 129.4 1.0 1.3e-37 129.4 1.0 2.4 2 0 0 2 2 2 1 Prp31 C terminal domain KLRAQ PF10205.9 GAN02639.1 - 1.8e-18 66.6 11.8 1.8e-18 66.6 11.8 6.9 4 3 2 6 6 6 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 GAN02639.1 - 1.5e-16 60.5 17.4 1.5e-16 60.5 17.4 3.4 3 1 0 3 3 3 1 Predicted coiled-coil domain-containing protein UPF0242 PF06785.11 GAN02639.1 - 0.00014 22.0 23.4 0.00014 22.0 23.4 5.8 3 2 0 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus Shugoshin_N PF07558.11 GAN02639.1 - 0.027 14.3 1.1 0.027 14.3 1.1 4.8 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 GAN02639.1 - 0.035 14.4 1.4 0.035 14.4 1.4 6.4 6 2 1 7 7 7 0 TSC-22/dip/bun family DivIC PF04977.15 GAN02639.1 - 0.044 13.6 0.8 0.044 13.6 0.8 10.3 7 3 5 12 12 12 0 Septum formation initiator Utp14 PF04615.13 GAN02640.1 - 8.2e-204 679.4 99.7 8.2e-204 679.4 99.7 2.0 1 1 1 2 2 2 1 Utp14 protein MPP6 PF10175.9 GAN02640.1 - 9.8e-07 29.3 7.5 9.8e-07 29.3 7.5 7.9 4 2 2 6 6 6 1 M-phase phosphoprotein 6 MFS_1 PF07690.16 GAN02641.1 - 1.2e-49 169.1 20.7 1.2e-49 169.1 20.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN02641.1 - 4.8e-09 35.6 13.9 4.8e-09 35.6 13.9 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 GAN02641.1 - 0.0061 15.0 1.4 0.012 14.1 1.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector SSF PF00474.17 GAN02643.1 - 2e-17 63.2 39.0 3.4e-17 62.4 39.0 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family NDK PF00334.19 GAN02644.1 - 1.1e-44 151.8 0.0 2.9e-44 150.3 0.0 1.8 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HSCB_C PF07743.13 GAN02645.1 - 5e-19 68.6 5.8 5e-19 68.6 5.8 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GAN02645.1 - 0.0001 22.3 1.9 0.00011 22.2 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain cwf21 PF08312.12 GAN02645.1 - 0.014 15.5 1.2 0.037 14.2 1.2 1.6 1 0 0 1 1 1 0 cwf21 domain DZR PF12773.7 GAN02645.1 - 0.072 13.1 0.6 0.12 12.4 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 GAN02645.1 - 0.098 12.4 1.0 0.16 11.7 1.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain RhoGEF PF00621.20 GAN02646.1 - 5e-38 131.2 5.9 1.7e-37 129.5 5.9 2.0 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 GAN02646.1 - 9.4e-27 93.1 0.1 3e-26 91.5 0.1 2.0 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 GAN02646.1 - 8.2e-20 71.3 0.7 1.9e-19 70.1 0.7 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 GAN02646.1 - 1.3e-13 50.7 0.3 3.2e-13 49.4 0.3 1.7 1 0 0 1 1 1 1 PB1 domain CH PF00307.31 GAN02646.1 - 0.0073 16.5 0.6 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain PH PF00169.29 GAN02646.1 - 0.032 14.7 1.5 0.14 12.7 0.3 2.4 2 0 0 2 2 2 0 PH domain SKA2 PF16740.5 GAN02646.1 - 0.065 13.0 1.7 0.31 10.8 0.1 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 PHM7_cyt PF14703.6 GAN02646.1 - 1.8 8.8 5.4 0.65 10.2 1.6 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TFIID-18kDa PF02269.16 GAN02647.1 - 0.093 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit NMT_C PF02799.15 GAN02649.1 - 3.2e-80 268.6 0.9 7.3e-80 267.4 0.9 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 GAN02649.1 - 4.7e-74 247.6 0.3 1.2e-73 246.3 0.0 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 GAN02649.1 - 0.0015 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family OKR_DC_1_C PF03711.15 GAN02649.1 - 0.056 13.7 0.5 0.17 12.2 0.5 1.7 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain Acetyltransf_9 PF13527.7 GAN02649.1 - 0.065 13.3 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 GAN02650.1 - 6.6e-107 357.2 35.5 3.9e-54 184.2 6.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN02650.1 - 2.2e-71 238.8 0.2 3.5e-36 124.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN02650.1 - 4.2e-16 59.0 5.2 3e-07 30.1 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GAN02650.1 - 2e-09 36.8 1.8 0.00078 18.3 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 GAN02650.1 - 3.3e-09 36.4 0.7 0.00043 20.0 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN02650.1 - 2e-08 34.6 3.0 0.012 15.9 0.3 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAN02650.1 - 6.6e-08 33.1 8.3 0.0017 18.7 0.3 3.9 3 2 0 3 3 2 2 AAA ATPase domain G-alpha PF00503.20 GAN02650.1 - 4e-07 29.5 0.1 0.0063 15.7 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 GAN02650.1 - 7.1e-07 29.1 1.0 0.017 14.8 0.1 3.9 2 2 1 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAN02650.1 - 1.2e-06 28.5 3.8 0.029 14.3 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 GAN02650.1 - 1.4e-05 25.0 0.3 0.49 10.1 0.1 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 GAN02650.1 - 2e-05 25.0 1.3 1.5 9.2 0.2 4.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAN02650.1 - 4e-05 23.2 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAN02650.1 - 5.7e-05 22.5 3.1 0.17 11.2 0.0 3.6 4 0 0 4 4 3 2 Zeta toxin DEAD PF00270.29 GAN02650.1 - 8.8e-05 22.3 2.0 0.1 12.4 0.3 3.2 2 1 0 2 2 2 2 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 GAN02650.1 - 0.0003 20.6 0.1 2.6 7.7 0.0 3.5 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 GAN02650.1 - 0.00034 20.6 0.1 1.6 8.8 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAN02650.1 - 0.00049 20.7 0.4 0.49 11.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAN02650.1 - 0.00062 19.9 0.2 2.7 8.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain Septin PF00735.18 GAN02650.1 - 0.0016 17.8 0.1 0.98 8.6 0.0 2.4 2 0 0 2 2 2 2 Septin AAA_24 PF13479.6 GAN02650.1 - 0.0017 18.1 0.1 1.5 8.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAN02650.1 - 0.0019 18.3 3.3 2.9 8.0 0.0 4.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 GAN02650.1 - 0.002 18.3 4.3 2 8.7 0.7 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 GAN02650.1 - 0.0022 18.5 0.6 0.6 10.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.20 GAN02650.1 - 0.0031 17.4 0.2 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_15 PF13175.6 GAN02650.1 - 0.0081 15.9 1.9 2.6 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain DUF87 PF01935.17 GAN02650.1 - 0.016 15.3 3.6 1.5 8.8 0.0 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain Roc PF08477.13 GAN02650.1 - 0.017 15.3 1.9 9.3 6.5 0.0 3.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 GAN02650.1 - 0.019 14.3 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAN02650.1 - 0.022 15.1 0.3 18 5.8 0.0 3.4 4 0 0 4 4 2 0 RNA helicase IstB_IS21 PF01695.17 GAN02650.1 - 0.026 14.2 1.6 1.9 8.2 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 GAN02650.1 - 0.027 14.0 0.4 14 5.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 GAN02650.1 - 0.052 13.5 2.7 1.6 8.6 0.0 3.2 4 0 0 4 4 2 0 NACHT domain AAA_28 PF13521.6 GAN02650.1 - 0.052 13.8 0.0 6.5 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAN02650.1 - 0.067 12.5 2.2 6.6 6.0 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family ECH_2 PF16113.5 GAN02650.1 - 0.086 12.3 2.4 1.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase Ploopntkinase3 PF18751.1 GAN02650.1 - 0.087 12.7 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 GMC_oxred_N PF00732.19 GAN02650.1 - 0.09 12.1 0.3 0.9 8.8 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Tim17 PF02466.19 GAN02650.1 - 0.17 12.3 1.6 0.86 10.0 1.6 2.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family AAA_17 PF13207.6 GAN02650.1 - 0.2 12.1 0.9 35 4.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain bZIP_1 PF00170.21 GAN02651.1 - 1.6e-06 28.1 5.6 1.6e-06 28.1 5.6 1.8 1 1 1 2 2 2 1 bZIP transcription factor phiKZ_IP PF12699.7 GAN02651.1 - 0.0063 15.7 0.7 0.008 15.4 0.7 1.1 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins bZIP_2 PF07716.15 GAN02651.1 - 0.0083 16.2 5.2 0.0083 16.2 5.2 2.8 1 1 1 2 2 2 1 Basic region leucine zipper Med11 PF10280.9 GAN02651.1 - 0.012 16.0 2.0 0.016 15.6 2.0 1.2 1 0 0 1 1 1 0 Mediator complex protein Sec8_exocyst PF04048.14 GAN02651.1 - 0.015 15.2 2.6 0.023 14.6 2.6 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Paralemmin PF03285.15 GAN02651.1 - 0.015 14.9 2.0 0.019 14.6 2.0 1.2 1 0 0 1 1 1 0 Paralemmin DUF812 PF05667.11 GAN02651.1 - 0.018 14.0 4.8 0.022 13.7 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DMPK_coil PF08826.10 GAN02651.1 - 0.024 14.7 3.2 0.038 14.1 2.7 1.6 1 1 0 1 1 1 0 DMPK coiled coil domain like DUF4200 PF13863.6 GAN02651.1 - 0.027 14.9 9.0 0.038 14.4 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.8 GAN02651.1 - 0.038 14.1 11.9 0.052 13.6 11.9 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SMC_ScpA PF02616.14 GAN02651.1 - 0.045 13.6 2.7 0.058 13.3 2.7 1.1 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Herpes_UL6 PF01763.16 GAN02651.1 - 0.057 11.9 1.4 0.066 11.7 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FlxA PF14282.6 GAN02651.1 - 0.22 11.5 6.3 0.45 10.5 6.0 1.7 1 1 0 1 1 1 0 FlxA-like protein UPF0242 PF06785.11 GAN02651.1 - 1 9.4 7.2 1.4 9.0 7.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 GAN02651.1 - 1.4 8.2 5.9 1.6 8.0 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 GAN02651.1 - 2.4 8.5 9.6 3.4 8.0 9.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fungal_trans PF04082.18 GAN02652.1 - 2.5e-17 62.8 1.4 2.5e-17 62.8 1.4 2.7 2 1 1 3 3 3 1 Fungal specific transcription factor domain Spt20 PF12090.8 GAN02652.1 - 0.0007 19.3 9.0 0.0007 19.3 9.0 3.3 3 0 0 3 3 3 1 Spt20 family Peptidase_M76 PF09768.9 GAN02653.1 - 5.5e-71 237.8 7.2 8.8e-71 237.2 7.2 1.3 1 0 0 1 1 1 1 Peptidase M76 family DEAD PF00270.29 GAN02653.1 - 1.5e-49 168.2 0.0 7.7e-49 165.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN02653.1 - 2e-32 111.8 0.1 7e-32 110.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN02653.1 - 9.9e-05 22.4 0.0 0.00099 19.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAN02653.1 - 0.017 13.9 0.0 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_30 PF13604.6 GAN02653.1 - 0.058 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain TB2_DP1_HVA22 PF03134.19 GAN02654.1 - 1.1e-29 102.2 6.1 1.1e-29 102.2 6.1 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family GUCT PF08152.12 GAN02655.1 - 0.012 15.9 0.2 0.072 13.4 0.1 2.4 2 0 0 2 2 2 0 GUCT (NUC152) domain DUF4677 PF15726.5 GAN02655.1 - 0.65 10.1 2.9 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4677) SH3_1 PF00018.28 GAN02656.1 - 4.1e-11 42.3 0.1 9.8e-11 41.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN02656.1 - 5.6e-10 38.9 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 GAN02656.1 - 3.5e-07 30.4 1.1 1.2e-06 28.7 1.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 GAN02656.1 - 7.5e-07 28.7 0.0 1.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DSPc PF00782.20 GAN02658.1 - 2.5e-05 24.1 0.0 3.5e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN02658.1 - 8.8e-05 22.2 0.0 0.0002 21.0 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAN02658.1 - 0.0068 16.5 0.0 0.0097 16.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate adh_short PF00106.25 GAN02659.1 - 4.6e-22 78.4 0.5 8.3e-22 77.6 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN02659.1 - 2.6e-13 50.1 0.1 4e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN02659.1 - 0.00071 19.5 0.2 0.0023 17.9 0.2 1.8 1 1 0 1 1 1 1 KR domain DUF2585 PF10755.9 GAN02660.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) AAA PF00004.29 GAN02661.1 - 0.051 14.0 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-grasp_2 PF08442.10 GAN02662.1 - 1.7e-75 253.1 0.0 2.8e-75 252.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 GAN02662.1 - 7.8e-25 87.5 0.5 1.2e-24 86.8 0.5 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GAN02662.1 - 5e-08 32.7 0.0 8.6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAN02662.1 - 5.9e-05 22.9 0.3 0.02 14.7 0.0 2.9 2 1 1 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 6PF2K PF01591.18 GAN02663.1 - 1.6e-72 243.4 0.1 2.4e-72 242.8 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAN02663.1 - 3.4e-21 75.8 0.0 1.2e-08 34.8 0.0 3.5 3 1 1 4 4 4 3 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAN02663.1 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAN02663.1 - 0.00019 21.0 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 GAN02663.1 - 0.014 14.6 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 GAN02663.1 - 0.054 13.9 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 GAN02664.1 - 3.9e-105 352.3 19.1 4.8e-105 352.0 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN02664.1 - 3.1e-28 98.7 30.7 2e-22 79.6 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN02664.1 - 0.00089 17.8 1.1 0.00089 17.8 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Viral_protease PF08715.10 GAN02664.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Papain like viral protease OATP PF03137.20 GAN02664.1 - 0.55 8.5 8.5 2.9 6.1 1.2 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RNase_T PF00929.24 GAN02665.1 - 6.8e-32 111.3 0.2 8.5e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 GAN02665.1 - 0.0054 16.7 0.0 0.0063 16.5 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like NKWYS PF10364.9 GAN02665.1 - 0.085 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein zf-RanBP PF00641.18 GAN02666.1 - 5.2e-32 108.8 52.0 3.6e-08 32.6 4.0 5.3 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others RNase_T PF00929.24 GAN02666.1 - 4.7e-08 33.8 0.7 1e-07 32.6 0.0 1.9 2 0 0 2 2 2 1 Exonuclease RRM_1 PF00076.22 GAN02666.1 - 6.2e-07 29.1 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Caldesmon PF02029.15 GAN02666.1 - 0.019 13.7 14.1 0.029 13.1 14.1 1.3 1 0 0 1 1 1 0 Caldesmon AAA-ATPase_like PF09820.9 GAN02666.1 - 2.3 7.5 5.1 3.8 6.8 5.1 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase TFIIA PF03153.13 GAN02666.1 - 4.6 7.1 26.3 4 7.3 5.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TP53IP5 PF15331.6 GAN02666.1 - 6.2 6.9 8.6 16 5.5 8.6 1.7 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 BORCS6 PF10157.9 GAN02667.1 - 4e-12 46.6 4.1 4.3e-12 46.5 4.1 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Fib_alpha PF08702.10 GAN02667.1 - 0.0041 17.3 8.6 0.0053 16.9 8.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 GAN02667.1 - 0.0043 17.1 7.3 0.06 13.4 1.4 2.0 2 0 0 2 2 2 1 Laminin Domain II FlxA PF14282.6 GAN02667.1 - 0.0046 16.9 17.4 0.19 11.7 3.8 2.0 1 1 1 2 2 2 2 FlxA-like protein Syntaxin_2 PF14523.6 GAN02667.1 - 0.0048 17.2 11.6 0.0088 16.4 11.6 1.5 1 1 0 1 1 1 1 Syntaxin-like protein Baculo_PEP_C PF04513.12 GAN02667.1 - 0.0048 16.9 9.2 0.014 15.4 9.2 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 GAN02667.1 - 0.0091 16.3 10.2 0.21 11.9 2.3 2.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 GAN02667.1 - 0.013 15.2 1.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 AAA_32 PF13654.6 GAN02667.1 - 0.014 14.2 5.2 0.014 14.2 5.2 1.1 1 0 0 1 1 1 0 AAA domain FlgN PF05130.12 GAN02667.1 - 0.017 15.6 10.0 0.022 15.3 10.0 1.0 1 0 0 1 1 1 0 FlgN protein ANAPC4 PF12896.7 GAN02667.1 - 0.021 14.3 6.0 0.021 14.3 3.4 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF1664 PF07889.12 GAN02667.1 - 0.027 14.5 6.3 0.038 14.0 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NOG1_N PF17835.1 GAN02667.1 - 0.032 14.2 2.0 0.062 13.3 2.0 1.4 1 1 0 1 1 1 0 NOG1 N-terminal helical domain ATP-synt_D PF01813.17 GAN02667.1 - 0.033 14.0 5.1 0.11 12.3 5.1 1.8 1 1 0 1 1 1 0 ATP synthase subunit D Spc7 PF08317.11 GAN02667.1 - 0.034 13.0 9.8 0.045 12.6 9.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MCPsignal PF00015.21 GAN02667.1 - 0.036 13.9 5.3 0.054 13.3 5.3 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TraC PF07820.12 GAN02667.1 - 0.038 14.3 0.3 0.095 13.0 0.1 1.7 1 1 1 2 2 2 0 TraC-like protein V_ATPase_I PF01496.19 GAN02667.1 - 0.049 11.6 5.7 0.056 11.4 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 GAN02667.1 - 0.055 13.7 10.1 0.15 12.3 10.1 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mce4_CUP1 PF11887.8 GAN02667.1 - 0.057 12.9 2.5 0.066 12.7 2.5 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3347 PF11827.8 GAN02667.1 - 0.062 13.5 5.5 0.075 13.2 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) LKAAEAR PF15478.6 GAN02667.1 - 0.062 13.6 2.8 0.079 13.2 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif DUF2408 PF10303.9 GAN02667.1 - 0.063 13.8 5.8 0.082 13.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1759 PF03564.15 GAN02667.1 - 0.071 13.0 3.3 0.41 10.6 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Sec34 PF04136.15 GAN02667.1 - 0.089 12.7 9.4 0.21 11.5 7.3 2.1 1 1 2 3 3 3 0 Sec34-like family BRE1 PF08647.11 GAN02667.1 - 0.1 12.7 12.3 0.37 10.9 10.7 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 GAN02667.1 - 0.13 12.6 7.6 1.4 9.2 0.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF725 PF05267.12 GAN02667.1 - 0.14 12.2 5.3 2.8 7.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF725) TPR_MLP1_2 PF07926.12 GAN02667.1 - 0.14 12.2 13.0 0.37 10.9 13.0 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 GAN02667.1 - 0.14 12.6 8.5 49 4.5 8.5 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 GAN02667.1 - 0.16 12.5 5.5 0.24 12.0 5.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 GAN02667.1 - 0.18 11.1 8.9 0.4 10.0 8.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2802 PF10975.8 GAN02667.1 - 0.19 11.9 6.0 0.85 9.8 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Exonuc_VII_L PF02601.15 GAN02667.1 - 0.21 11.1 6.1 0.22 11.0 6.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rx_N PF18052.1 GAN02667.1 - 0.23 11.7 4.1 0.34 11.2 0.7 2.1 1 1 1 2 2 2 0 Rx N-terminal domain DHR10 PF18595.1 GAN02667.1 - 0.32 11.1 13.5 0.31 11.1 2.2 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain RmuC PF02646.16 GAN02667.1 - 0.36 9.9 10.1 0.2 10.8 3.0 2.1 1 1 1 2 2 2 0 RmuC family DASH_Dad2 PF08654.10 GAN02667.1 - 0.37 11.2 8.3 0.71 10.3 2.1 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 GAN02667.1 - 0.42 10.9 8.7 4.8 7.4 2.0 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fzo_mitofusin PF04799.13 GAN02667.1 - 0.48 10.0 10.0 2 8.0 4.3 2.0 1 1 1 2 2 2 0 fzo-like conserved region ApoC-I PF04691.12 GAN02667.1 - 0.5 10.3 5.4 5.7 6.9 0.2 3.0 1 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) CENP-Q PF13094.6 GAN02667.1 - 0.56 10.4 9.6 2.9 8.1 9.6 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spike_torovirin PF17072.5 GAN02667.1 - 0.69 7.0 4.8 0.71 6.9 4.8 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein GAT PF03127.14 GAN02667.1 - 0.83 10.0 8.4 3.6 8.0 1.5 2.3 1 1 1 2 2 2 0 GAT domain YabA PF06156.13 GAN02667.1 - 1 10.0 7.8 13 6.5 4.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA PilO PF04350.13 GAN02667.1 - 1.2 9.3 10.7 2.8 8.1 0.6 2.0 1 1 1 2 2 2 0 Pilus assembly protein, PilO Uso1_p115_C PF04871.13 GAN02667.1 - 1.4 9.3 13.0 31 5.0 13.0 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ACCA PF03255.14 GAN02667.1 - 1.8 8.4 6.1 1.1 9.1 2.8 1.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LPP PF04728.13 GAN02667.1 - 2.2 8.8 11.2 2.5 8.6 1.1 3.0 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Ribosomal_L7Ae PF01248.26 GAN02668.1 - 4.6e-26 90.4 0.0 5.3e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family tRNA-synt_1c PF00749.21 GAN02669.1 - 1.7e-95 319.6 0.0 4.7e-93 311.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MDD_C PF18376.1 GAN02670.1 - 1e-73 247.1 0.0 1.6e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GAN02670.1 - 3.3e-07 30.4 2.0 6.5e-07 29.5 2.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DnaJ PF00226.31 GAN02671.1 - 3.2e-21 75.2 0.5 3.5e-20 71.9 0.0 2.8 2 0 0 2 2 2 1 DnaJ domain RMI1_N PF08585.12 GAN02671.1 - 1.2e-12 48.1 0.4 1.2e-12 48.1 0.4 6.6 3 2 2 6 6 6 2 RecQ mediated genome instability protein MTHFR PF02219.17 GAN02672.1 - 7.3e-115 383.2 0.0 9.9e-115 382.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HMG_box PF00505.19 GAN02673.1 - 2.1e-25 88.9 1.8 2.1e-25 88.9 1.8 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN02673.1 - 8.8e-18 64.7 2.4 8.8e-18 64.7 2.4 1.6 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 GAN02673.1 - 0.00012 22.0 1.1 0.00012 22.0 1.1 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CHDNT PF08073.12 GAN02673.1 - 0.0002 21.2 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain Ccdc124 PF06244.12 GAN02673.1 - 0.012 16.2 2.2 0.012 16.2 2.2 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 GAN02673.1 - 0.24 12.0 2.0 0.19 12.3 1.1 1.4 1 1 0 1 1 1 0 YABBY protein HVSL PF09749.9 GAN02675.1 - 8.1e-07 28.8 0.1 1.2e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3395 PF11875.8 GAN02676.1 - 3.3e-44 150.5 0.5 3.3e-44 150.5 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 GAN02676.1 - 3.7e-19 68.6 3.8 4.7e-19 68.3 1.1 2.3 2 0 0 2 2 2 1 DnaJ domain NUMOD3 PF07460.11 GAN02676.1 - 0.039 14.2 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Chitin_synth_2 PF03142.15 GAN02677.1 - 4e-239 794.6 2.2 6.2e-239 794.0 2.2 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAN02677.1 - 6.1e-14 52.5 0.1 1.2e-13 51.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN02677.1 - 7.9e-11 42.2 13.1 5.5e-10 39.5 7.3 2.9 2 1 0 2 2 2 2 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GAN02677.1 - 2.9e-05 23.6 0.2 0.00027 20.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAN02677.1 - 0.082 12.7 0.0 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 SARAF PF06682.12 GAN02677.1 - 0.25 10.9 0.0 0.25 10.9 0.0 3.9 2 1 2 4 4 4 0 SOCE-associated regulatory factor of calcium homoeostasis Dabb PF07876.12 GAN02678.1 - 6.6e-20 71.5 0.1 7.2e-20 71.4 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain p450 PF00067.22 GAN02680.1 - 1.2e-79 268.2 0.3 1.6e-79 267.8 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 Choline_transpo PF04515.12 GAN02680.1 - 0.053 12.7 0.2 0.084 12.1 0.2 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter RMI1_N PF08585.12 GAN02681.1 - 4.2e-38 131.3 0.1 1.2e-37 129.8 0.0 1.8 2 0 0 2 2 2 1 RecQ mediated genome instability protein TENA_THI-4 PF03070.16 GAN02682.1 - 3.3e-10 40.2 0.6 4.4e-09 36.5 0.6 2.2 1 1 0 1 1 1 1 TENA/THI-4/PQQC family CT_A_B PF02626.15 GAN02682.1 - 0.22 11.1 0.0 0.31 10.6 0.0 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B Cyt-b5 PF00173.28 GAN02683.1 - 4.1e-24 84.5 0.2 5e-24 84.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PDEase_I PF00233.19 GAN02684.1 - 7.9e-75 251.6 0.7 7.9e-75 251.6 0.7 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 GAN02684.1 - 0.036 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Response regulator receiver domain SUIM_assoc PF16619.5 GAN02684.1 - 0.058 13.5 0.4 0.058 13.5 0.4 2.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 UDG PF03167.19 GAN02685.1 - 2.9e-18 66.3 0.0 4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2833 PF11090.8 GAN02685.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) RNA_pol_Rpc82 PF05645.13 GAN02686.1 - 3.9e-22 79.2 0.6 6.9e-21 75.2 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 GAN02686.1 - 4.3e-22 78.0 0.1 1.7e-15 56.9 0.0 3.5 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 GAN02686.1 - 4.5e-06 26.5 0.0 0.0042 16.9 0.0 3.2 2 1 1 3 3 3 2 TFIIE alpha subunit TrmB PF01978.19 GAN02686.1 - 0.002 18.0 0.0 1.5 8.7 0.0 4.0 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.11 GAN02686.1 - 0.07 13.1 0.1 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF977) CbiZ PF01955.18 GAN02686.1 - 0.13 12.4 0.2 0.84 9.7 0.1 2.0 2 0 0 2 2 2 0 Adenosylcobinamide amidohydrolase HTH_IclR PF09339.10 GAN02686.1 - 0.17 11.7 0.1 0.85 9.5 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF3164 PF11363.8 GAN02687.1 - 0.085 12.5 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) Coatomer_E PF04733.14 GAN02688.1 - 5.6e-70 236.0 11.0 6.5e-70 235.8 11.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 GAN02688.1 - 6.5e-07 29.5 7.0 0.0087 16.3 0.3 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAN02688.1 - 3.2e-06 27.4 5.4 0.0011 19.2 0.8 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN02688.1 - 4.9e-05 23.7 17.1 0.04 14.4 0.1 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 GAN02688.1 - 0.00011 22.5 6.3 0.035 14.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 GAN02688.1 - 0.00037 20.2 1.5 0.00087 19.0 1.5 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_16 PF13432.6 GAN02688.1 - 0.0018 18.8 10.2 0.15 12.7 1.2 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GAN02688.1 - 0.011 15.7 4.5 0.35 10.9 0.2 2.9 2 2 1 3 3 3 0 Putative TPR-like repeat TPR_MalT PF17874.1 GAN02688.1 - 0.022 14.2 10.5 0.061 12.7 9.5 2.2 2 1 0 2 2 2 0 MalT-like TPR region DUF5588 PF17826.1 GAN02688.1 - 0.029 13.3 3.0 0.3 9.9 0.1 2.1 1 1 0 2 2 2 0 Family of unknown function (DUF5588) TPR_2 PF07719.17 GAN02688.1 - 0.086 13.0 8.9 0.8 10.0 0.2 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN02688.1 - 0.17 12.8 6.5 1.7 9.7 0.1 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAN02688.1 - 0.27 11.1 4.9 15 5.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN02688.1 - 0.33 10.9 4.8 4.5 7.2 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Snf7 PF03357.21 GAN02689.1 - 8.3e-39 132.9 17.0 1.2e-38 132.5 17.0 1.2 1 0 0 1 1 1 1 Snf7 DUF2890 PF11081.8 GAN02689.1 - 1.1 9.3 8.1 0.21 11.7 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) PTR2 PF00854.21 GAN02690.1 - 2.3e-54 184.8 3.6 2.8e-54 184.5 3.6 1.1 1 0 0 1 1 1 1 POT family DUF1633 PF07794.11 GAN02690.1 - 0.17 10.0 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Translin PF01997.16 GAN02691.1 - 1.2e-58 198.5 0.2 1.4e-58 198.3 0.2 1.0 1 0 0 1 1 1 1 Translin family Glyco_hydro_53 PF07745.13 GAN02691.1 - 0.0058 15.7 0.1 0.021 13.8 0.0 1.9 1 1 0 2 2 2 1 Glycosyl hydrolase family 53 Njmu-R1 PF15053.6 GAN02691.1 - 0.0072 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Mjmu-R1-like protein family Allantoicase PF03561.15 GAN02692.1 - 4.8e-77 256.8 0.0 2.7e-39 134.4 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat CorA PF01544.18 GAN02693.1 - 1.3e-49 169.1 0.1 1.9e-49 168.6 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein XhlA PF10779.9 GAN02693.1 - 0.51 10.6 2.5 0.56 10.5 0.5 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF1043 PF06295.12 GAN02694.1 - 0.11 12.5 0.3 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Mlh1_C PF16413.5 GAN02695.1 - 2.6e-80 269.7 3.3 5.8e-78 262.0 3.3 2.7 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GAN02695.1 - 2.6e-26 91.7 1.5 2.2e-23 82.2 0.1 3.0 3 0 0 3 3 3 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAN02695.1 - 6.8e-13 48.6 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAN02695.1 - 4.1e-06 27.3 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 GAN02695.1 - 0.026 14.3 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 MutL C terminal dimerisation domain CAF1 PF04857.20 GAN02695.1 - 0.046 12.9 0.3 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 CAF1 family ribonuclease Aminotran_3 PF00202.21 GAN02696.1 - 8.3e-123 410.0 0.0 9.5e-123 409.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAN02696.1 - 0.042 13.0 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II EF-hand_1 PF00036.32 GAN02697.1 - 2.3e-34 114.3 17.1 2e-09 36.3 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN02697.1 - 2.5e-32 111.1 5.0 1.4e-17 63.9 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAN02697.1 - 2e-26 91.6 15.0 4.5e-15 55.2 1.5 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAN02697.1 - 2.5e-26 89.3 11.6 2.4e-08 33.2 0.2 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAN02697.1 - 2.2e-24 83.8 18.1 3.8e-07 29.3 0.3 4.6 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAN02697.1 - 6.1e-13 48.9 0.1 2.6e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAN02697.1 - 1.6e-10 40.8 4.3 0.00096 19.1 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN02697.1 - 2.3e-07 31.1 0.2 0.00051 20.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAN02697.1 - 2.5e-06 27.6 8.3 0.036 14.3 0.7 3.2 1 1 3 4 4 4 4 Dockerin type I domain EF-hand_11 PF08976.11 GAN02697.1 - 0.0033 18.3 0.0 0.025 15.4 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 GAN02697.1 - 0.0094 15.9 0.2 0.6 10.1 0.1 2.4 1 1 1 2 2 2 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 GAN02697.1 - 0.01 16.1 0.1 0.032 14.6 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 GAN02697.1 - 0.016 15.1 0.6 3.8 7.4 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain SurA_N_3 PF13624.6 GAN02697.1 - 0.027 14.3 0.2 2.3 8.0 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF2267 PF10025.9 GAN02697.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF3349 PF11829.8 GAN02697.1 - 0.044 14.5 0.1 14 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 GAN02697.1 - 0.1 12.5 0.6 0.89 9.5 0.4 2.6 1 1 0 1 1 1 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 GAN02697.1 - 0.19 12.1 0.9 0.63 10.4 0.7 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb4 Ribosomal_S3Ae PF01015.18 GAN02698.1 - 6.4e-43 146.7 5.8 6.6e-29 100.9 3.1 2.0 1 1 1 2 2 2 2 Ribosomal S3Ae family DUF5025 PF16428.5 GAN02698.1 - 0.11 12.7 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5025) F-box-like PF12937.7 GAN02699.1 - 7.2e-12 45.0 0.4 2e-11 43.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN02699.1 - 3.8e-08 33.0 0.0 8.9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 GAN02699.1 - 0.087 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box IQ PF00612.27 GAN02700.1 - 1e-05 24.9 0.9 2.4e-05 23.7 0.9 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Lzipper-MIP1 PF14389.6 GAN02700.1 - 0.00066 19.9 14.3 0.0032 17.7 1.6 3.7 1 1 2 3 3 3 2 Leucine-zipper of ternary complex factor MIP1 CALCOCO1 PF07888.11 GAN02700.1 - 0.019 13.9 15.6 0.032 13.1 15.6 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CAT PF00302.18 GAN02700.1 - 0.086 12.8 2.4 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Chloramphenicol acetyltransferase betaPIX_CC PF16523.5 GAN02700.1 - 0.82 9.5 12.5 0.12 12.2 2.1 3.1 1 1 2 3 3 3 0 betaPIX coiled coil MRP-S23 PF10484.9 GAN02700.1 - 1.1 9.5 6.0 0.2 11.9 0.3 2.4 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 Phasin PF05597.11 GAN02700.1 - 3.2 7.8 8.3 4.5 7.3 6.9 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MFS_1 PF07690.16 GAN02703.1 - 8.7e-24 84.1 40.9 8.7e-24 84.1 40.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily F_actin_cap_B PF01115.17 GAN02704.1 - 6.4e-106 353.3 0.0 8.9e-106 352.9 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Lectin_leg-like PF03388.13 GAN02704.1 - 1.5e-71 240.4 0.1 2.1e-71 239.9 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 GAN02704.1 - 1e-08 35.4 0.3 1.9e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 GAN02704.1 - 7.1e-06 25.7 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain F-actin_cap_A PF01267.17 GAN02704.1 - 1.3e-05 24.8 0.2 0.00046 19.7 0.0 2.5 1 1 1 2 2 2 1 F-actin capping protein alpha subunit Flavi_NS1 PF00948.21 GAN02704.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Rrn6 PF10214.9 GAN02706.1 - 4.5e-07 28.8 23.1 0.003 16.1 14.1 3.1 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor SATase_N PF06426.14 GAN02706.1 - 0.022 15.1 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Zn_clus PF00172.18 GAN02707.1 - 8.1e-05 22.7 10.7 8.1e-05 22.7 10.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAN02707.1 - 0.00041 20.3 0.0 0.00079 19.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold HSA PF07529.13 GAN02708.1 - 9.1e-14 51.5 3.7 9.1e-14 51.5 3.7 6.9 7 1 0 7 7 7 1 HSA Myb_DNA-bind_6 PF13921.6 GAN02708.1 - 2.8e-09 37.1 2.4 1.4e-08 34.9 0.9 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN02708.1 - 0.00012 22.1 0.3 0.00034 20.7 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain G10 PF01125.17 GAN02710.1 - 2.2e-70 235.1 4.3 2.5e-70 234.9 4.3 1.0 1 0 0 1 1 1 1 G10 protein LBR_tudor PF09465.10 GAN02710.1 - 1.3 8.9 3.4 0.89 9.4 0.9 2.0 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Mito_carr PF00153.27 GAN02711.1 - 1.9e-55 184.8 3.3 1.3e-22 79.5 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein PDR_assoc PF08370.11 GAN02711.1 - 0.029 14.1 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_2 PF07724.14 GAN02713.1 - 1.8e-44 151.9 1.1 1.3e-43 149.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAN02713.1 - 6.7e-16 58.9 1.0 4.5e-15 56.2 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAN02713.1 - 4.2e-12 45.9 0.1 4.2e-12 45.9 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAN02713.1 - 7.4e-07 29.2 0.1 2.4e-06 27.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAN02713.1 - 3e-06 26.8 0.3 0.0012 18.2 0.1 3.3 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAN02713.1 - 1.3e-05 25.0 1.2 0.0032 17.2 0.0 2.6 3 0 0 3 3 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 GAN02713.1 - 4.7e-05 23.5 0.0 0.0019 18.3 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 GAN02713.1 - 6.2e-05 23.3 4.1 0.0027 18.0 0.3 3.4 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 GAN02713.1 - 0.00015 21.5 3.0 0.012 15.3 0.0 2.9 4 0 0 4 4 2 1 Sigma-54 interaction domain MCM PF00493.23 GAN02713.1 - 0.00026 20.2 0.1 0.0023 17.0 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain ABC_tran PF00005.27 GAN02713.1 - 0.00037 21.0 2.2 0.021 15.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.12 GAN02713.1 - 0.002 17.9 4.2 0.0042 16.8 0.1 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 GAN02713.1 - 0.002 17.9 0.7 0.006 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GAN02713.1 - 0.0033 17.4 1.3 0.36 10.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 GAN02713.1 - 0.0034 17.6 1.8 0.039 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAN02713.1 - 0.0034 16.9 0.0 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Spt20 PF12090.8 GAN02713.1 - 0.0048 16.5 14.5 0.0086 15.7 14.5 1.4 1 0 0 1 1 1 1 Spt20 family AAA_16 PF13191.6 GAN02713.1 - 0.0057 17.1 0.1 0.0057 17.1 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 GAN02713.1 - 0.0073 16.3 0.4 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAN02713.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 GAN02713.1 - 0.008 16.7 7.7 1.9 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAN02713.1 - 0.023 13.8 4.1 0.062 12.4 4.1 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 GAN02713.1 - 0.024 15.2 0.6 0.32 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAN02713.1 - 0.025 14.5 1.3 0.065 13.1 0.0 2.3 3 0 0 3 3 2 0 NACHT domain SKI PF01202.22 GAN02713.1 - 0.027 14.6 1.9 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.6 GAN02713.1 - 0.034 14.4 2.9 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 GAN02713.1 - 0.038 13.2 1.2 0.11 11.7 0.0 2.1 2 1 0 2 2 2 0 TIP49 P-loop domain AAA_29 PF13555.6 GAN02713.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 GAN02713.1 - 0.063 13.1 0.1 0.18 11.6 0.0 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_3 PF07726.11 GAN02713.1 - 0.069 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_8 PF12780.7 GAN02713.1 - 0.096 12.0 2.1 0.61 9.4 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 Ctr PF04145.15 GAN02713.1 - 0.1 13.2 0.5 0.21 12.2 0.5 1.5 1 0 0 1 1 1 0 Ctr copper transporter family RNA_helicase PF00910.22 GAN02713.1 - 0.15 12.4 0.4 0.5 10.8 0.0 2.2 2 0 0 2 2 1 0 RNA helicase FA_desaturase PF00487.24 GAN02713.1 - 0.17 11.7 1.2 0.27 11.0 1.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DEAD PF00270.29 GAN02713.1 - 0.41 10.4 0.0 0.41 10.4 0.0 2.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase Peptidase_S49_N PF08496.10 GAN02713.1 - 0.74 9.9 6.6 1.5 8.9 6.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4834 PF16118.5 GAN02713.1 - 0.83 10.7 5.3 2.6 9.1 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_17 PF13207.6 GAN02713.1 - 0.83 10.1 3.5 40 4.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain Fe-ADH_2 PF13685.6 GAN02713.1 - 1 9.0 5.0 13 5.4 5.0 2.3 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase ATPase PF06745.13 GAN02713.1 - 1.5 8.2 5.6 3.2 7.0 0.3 3.0 2 1 0 2 2 2 0 KaiC Presenilin PF01080.17 GAN02713.1 - 5.4 5.7 6.8 7.7 5.2 6.8 1.2 1 0 0 1 1 1 0 Presenilin CDC13_N PF16853.5 GAN02713.1 - 6.5 6.2 10.4 13 5.2 8.2 2.2 2 0 0 2 2 2 0 Cell division control protein 13 N-terminus Androgen_recep PF02166.16 GAN02713.1 - 6.5 5.5 15.2 11 4.8 15.2 1.3 1 0 0 1 1 1 0 Androgen receptor Gar1 PF04410.14 GAN02714.1 - 6.3e-35 120.2 0.1 8e-35 119.9 0.1 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region ARS2 PF04959.13 GAN02715.1 - 1.4e-21 77.8 0.1 1.4e-21 77.8 0.1 2.0 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 GAN02715.1 - 3.6e-19 69.0 4.5 3.6e-19 69.0 4.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 GAN02715.1 - 2.4e-09 36.8 5.8 5.6e-09 35.6 5.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 GAN02715.1 - 0.00062 19.5 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBECR3 PF18812.1 GAN02715.1 - 0.077 13.0 3.0 0.41 10.6 1.5 2.5 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 zf-C2H2 PF00096.26 GAN02715.1 - 0.13 12.8 0.3 0.13 12.8 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type SWIB PF02201.18 GAN02716.1 - 1.1e-21 76.5 0.1 2.9e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Yip1 PF04893.17 GAN02716.1 - 3.1e-06 27.0 3.3 5.3e-06 26.3 3.3 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2955 PF11168.8 GAN02716.1 - 0.0055 16.6 2.6 0.009 15.9 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2955) DUF2374 PF09574.10 GAN02716.1 - 0.017 14.9 1.6 0.058 13.2 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (Duf2374) zf-C2H2_2 PF12756.7 GAN02717.1 - 4.8e-05 23.6 0.0 7.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF2735 PF10931.8 GAN02717.1 - 0.086 13.5 0.1 0.18 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) zf-C2H2_4 PF13894.6 GAN02717.1 - 0.14 13.0 0.5 0.14 13.0 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 GAN02717.1 - 0.26 11.2 0.2 0.26 11.2 0.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 GAN02717.1 - 0.26 11.8 0.6 0.26 11.8 0.6 2.7 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 GAN02717.1 - 0.6 10.4 5.0 1.4 9.3 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 GAN02718.1 - 4.2e-06 27.0 2.1 2e-05 24.8 0.8 2.2 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN02718.1 - 0.00079 20.1 9.7 0.11 13.4 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 GAN02718.1 - 0.00095 19.4 5.7 0.014 15.7 0.3 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 GAN02718.1 - 0.0022 18.3 9.4 0.16 12.5 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-BED PF02892.15 GAN02718.1 - 0.039 14.0 1.6 0.039 14.0 1.6 2.4 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_9 PF16293.5 GAN02718.1 - 0.047 13.5 1.7 7.8 6.4 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 GAN02718.1 - 0.1 13.3 2.1 1.7 9.3 0.3 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 GAN02718.1 - 0.18 11.9 2.1 5.1 7.2 0.1 2.3 1 1 1 2 2 2 0 CpXC protein FOXP-CC PF16159.5 GAN02718.1 - 0.24 12.0 2.5 4.3 8.0 0.1 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain Gp_dh_C PF02800.20 GAN02719.1 - 3.6e-71 237.9 0.2 5.6e-71 237.3 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAN02719.1 - 2.8e-38 130.3 0.1 5.4e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2804 PF10974.8 GAN02719.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) ADH_zinc_N PF00107.26 GAN02719.1 - 0.042 13.8 0.2 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DapB_N PF01113.20 GAN02719.1 - 0.059 13.5 0.6 0.22 11.7 0.0 2.2 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.24 GAN02720.1 - 4e-103 345.7 31.0 7.6e-53 180.0 5.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN02720.1 - 4.3e-28 98.2 29.5 1.2e-27 96.8 22.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4947 PF16305.5 GAN02720.1 - 0.07 13.1 0.4 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Chitin_synth_2 PF03142.15 GAN02721.1 - 6.9e-238 790.5 1.5 6.9e-238 790.5 1.5 1.6 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 GAN02721.1 - 5e-76 256.4 5.3 5.7e-72 243.0 1.1 3.2 1 1 1 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 GAN02721.1 - 4.8e-18 64.8 0.8 5.8e-17 61.3 1.0 2.6 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 GAN02721.1 - 3e-15 56.1 0.1 2.6e-09 37.1 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAN02721.1 - 2.4e-13 50.5 5.4 3e-13 50.1 2.6 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAN02721.1 - 2.3e-12 47.3 0.0 1.9e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAN02721.1 - 1.5e-05 24.9 0.0 0.021 14.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN02721.1 - 0.017 14.6 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 21 T2SSE PF00437.20 GAN02721.1 - 0.03 13.4 0.0 0.088 11.8 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 GAN02721.1 - 0.046 13.8 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 GAN02721.1 - 0.075 12.3 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 GAN02721.1 - 0.32 11.3 1.2 2.7 8.2 0.1 2.9 3 0 0 3 3 3 0 AAA domain GARP PF16731.5 GAN02721.1 - 1.2 8.8 18.2 2.3 7.9 18.2 1.4 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma AAA_16 PF13191.6 GAN02721.1 - 3 8.2 4.4 0.86 10.0 0.0 2.3 2 0 0 2 2 1 0 AAA ATPase domain Na_Ca_ex PF01699.24 GAN02722.1 - 1.3e-20 73.9 38.8 5.9e-15 55.5 11.5 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 GAN02722.1 - 6.4e-14 52.4 8.2 6.4e-14 52.4 8.2 4.2 5 0 0 5 5 5 1 Inner membrane component domain DUF3180 PF11377.8 GAN02722.1 - 1.4 9.0 8.7 8.5 6.5 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) STIMATE PF12400.8 GAN02723.1 - 1.3e-33 116.2 9.0 1.9e-33 115.7 9.0 1.2 1 0 0 1 1 1 1 STIMATE family Abhydrolase_3 PF07859.13 GAN02724.1 - 7.1e-31 107.7 0.0 1.1e-30 107.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN02724.1 - 6e-16 58.3 0.8 2.8e-15 56.0 0.8 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 GAN02724.1 - 0.0025 16.8 0.0 0.51 9.2 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 GAN02724.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_C14 PF00656.22 GAN02724.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Caspase domain ACP_syn_III_C PF08541.10 GAN02724.1 - 0.031 14.5 0.0 8 6.7 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Hydrolase_3 PF08282.12 GAN02724.1 - 0.091 12.5 0.3 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Abhydrolase_2 PF02230.16 GAN02724.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAN02724.1 - 0.2 12.2 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SIKE PF05769.11 GAN02725.1 - 1.4e-05 25.1 20.3 3.7e-05 23.7 20.3 1.8 1 1 0 1 1 1 1 SIKE family Med10 PF09748.9 GAN02725.1 - 0.56 10.2 10.2 2.7 8.0 1.1 3.0 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF4094 PF13334.6 GAN02725.1 - 2 8.9 10.4 3.8 8.0 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DUF4600 PF15372.6 GAN02725.1 - 2.4 8.6 15.3 0.13 12.8 5.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Swi5 PF07061.11 GAN02725.1 - 2.6 8.2 14.6 0.92 9.6 0.1 3.9 2 1 1 3 3 3 0 Swi5 FlaC_arch PF05377.11 GAN02725.1 - 3.5 8.1 11.0 19 5.8 0.3 4.5 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 GAN02725.1 - 5.3 7.5 15.5 0.44 10.9 3.5 3.2 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF802 PF05650.11 GAN02725.1 - 8.6 6.9 12.9 4.2 7.9 5.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF802) Caleosin PF05042.13 GAN02726.1 - 0.0018 18.3 0.5 0.01 15.8 0.5 2.1 1 1 0 1 1 1 1 Caleosin related protein MTP18 PF10558.9 GAN02727.1 - 6.4e-63 211.8 4.8 3.5e-31 108.5 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Pkinase PF00069.25 GAN02728.1 - 5.7e-70 235.7 0.0 7.5e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02728.1 - 5.5e-33 114.4 0.0 9.1e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN02728.1 - 0.00015 20.9 0.2 0.00086 18.3 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 GAN02728.1 - 0.00067 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN02728.1 - 0.025 14.5 0.2 0.11 12.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_49 PF13896.6 GAN02729.1 - 4.4e-58 197.2 3.5 2.2e-47 162.0 2.4 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 GAN02729.1 - 0.00062 20.2 0.5 0.0017 18.8 0.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAN02729.1 - 0.0032 17.0 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3336 PF11815.8 GAN02730.1 - 6.7e-32 110.1 0.3 1.4e-31 109.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAN02730.1 - 5.2e-16 59.4 0.0 1.2e-15 58.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase PAF PF15715.5 GAN02730.1 - 0.16 12.5 0.6 0.29 11.7 0.6 1.4 1 0 0 1 1 1 0 PCNA-associated factor histone like domain HLH PF00010.26 GAN02731.1 - 4.1e-14 52.3 2.6 7.5e-14 51.4 2.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 GAN02731.1 - 3.8 7.0 20.9 0.78 9.3 14.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zinc_ribbon_4 PF13717.6 GAN02732.1 - 0.0015 18.4 4.6 0.62 10.0 0.0 2.6 3 0 0 3 3 3 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAN02732.1 - 0.004 17.2 3.3 0.0062 16.6 3.3 1.3 1 0 0 1 1 1 1 Zinc ribbon domain NOB1_Zn_bind PF08772.11 GAN02732.1 - 0.01 16.0 1.0 0.016 15.4 1.0 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 GAN02732.1 - 0.025 14.0 1.3 0.57 9.7 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 GAN02732.1 - 0.035 14.1 0.8 0.055 13.5 0.8 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-FPG_IleRS PF06827.14 GAN02732.1 - 0.043 13.7 2.2 0.044 13.6 0.7 1.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.7 GAN02732.1 - 0.074 13.0 1.4 3.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.6 GAN02732.1 - 0.11 12.2 4.7 20 5.1 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 GAN02732.1 - 0.14 12.5 3.4 0.32 11.3 3.4 1.7 1 1 0 1 1 1 0 zinc-ribbon zf-C2H2_4 PF13894.6 GAN02732.1 - 0.18 12.7 2.7 5.9 8.0 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.19 GAN02732.1 - 0.23 11.5 2.9 0.31 11.1 2.7 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_6 PF13912.6 GAN02732.1 - 2.9 8.0 7.2 0.39 10.8 2.4 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN02732.1 - 4.5 7.9 6.7 2 9.0 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type FA_desaturase PF00487.24 GAN02733.1 - 0.97 9.2 3.2 0.36 10.6 0.3 1.6 1 1 1 2 2 2 0 Fatty acid desaturase Tetraspanin PF00335.20 GAN02733.1 - 7.6 6.2 10.6 13 5.4 10.6 1.4 1 0 0 1 1 1 0 Tetraspanin family LIM PF00412.22 GAN02734.1 - 1.8e-21 76.1 49.8 4.8e-11 42.7 8.2 4.9 5 0 0 5 5 5 4 LIM domain NTP_transferase PF00483.23 GAN02735.1 - 4.6e-30 105.0 0.0 6.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAN02735.1 - 1.3e-08 34.2 5.5 1.8e-05 24.3 0.2 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAN02735.1 - 3.2e-08 34.1 0.0 5.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 GAN02735.1 - 0.0038 16.2 0.9 0.022 13.7 0.9 2.1 1 1 0 1 1 1 1 L-fucokinase DUF4969 PF16339.5 GAN02735.1 - 0.098 13.0 0.0 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Pro_dh PF01619.18 GAN02738.1 - 1.9e-72 244.3 1.1 1.1e-71 241.8 1.1 2.0 1 1 0 1 1 1 1 Proline dehydrogenase GCP_C_terminal PF04130.13 GAN02739.1 - 1.4e-52 179.1 10.0 2.6e-52 178.2 10.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAN02739.1 - 1.9e-24 86.8 0.5 4e-24 85.8 0.5 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal ALO PF04030.14 GAN02740.1 - 1.6e-90 303.5 2.1 2.3e-90 302.9 2.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 GAN02740.1 - 3.4e-27 94.9 0.0 5.1e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Sec3_C PF09763.9 GAN02741.1 - 4.9e-136 454.9 14.1 4.9e-136 454.9 14.1 2.9 2 1 0 2 2 2 1 Exocyst complex component Sec3 PDT PF00800.18 GAN02741.1 - 1.1e-33 116.5 3.4 3.2e-26 92.3 1.9 3.4 1 1 1 2 2 2 2 Prephenate dehydratase CM_2 PF01817.21 GAN02741.1 - 6.6e-20 71.2 0.2 6.6e-20 71.2 0.2 3.3 2 0 0 2 2 2 1 Chorismate mutase type II Sec3-PIP2_bind PF15277.6 GAN02741.1 - 5.7e-18 64.8 0.3 1.3e-17 63.7 0.3 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH ACT PF01842.25 GAN02741.1 - 1.8e-06 27.6 0.0 8.4e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 ACT domain Vps52 PF04129.12 GAN02741.1 - 0.016 14.0 8.4 0.053 12.3 6.1 2.6 2 1 0 2 2 2 0 Vps52 / Sac2 family TFIIA PF03153.13 GAN02741.1 - 0.058 13.4 14.6 0.11 12.4 14.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4201 PF13870.6 GAN02741.1 - 0.26 11.0 14.6 0.061 13.1 9.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Adap_comp_sub PF00928.21 GAN02742.1 - 1.1e-28 100.4 0.0 2.1e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAN02742.1 - 3e-07 30.5 0.3 4.7e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4337 PF14235.6 GAN02742.1 - 0.01 16.0 3.8 0.022 14.9 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) EMC3_TMCO1 PF01956.16 GAN02742.1 - 0.19 11.4 0.9 0.37 10.5 0.9 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CDC37_N PF03234.14 GAN02742.1 - 0.44 11.5 8.4 1.1 10.1 0.1 3.0 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding zf-C2H2_2 PF12756.7 GAN02743.1 - 5.4e-35 119.8 14.7 6.1e-29 100.3 1.0 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAN02743.1 - 3.6e-08 33.5 9.6 9.9e-07 28.9 3.0 3.6 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN02743.1 - 5.5e-08 32.9 3.0 5.5e-08 32.9 3.0 3.0 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN02743.1 - 0.00062 20.4 10.6 0.038 14.8 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN02743.1 - 0.0034 17.8 12.8 0.067 13.7 1.1 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type Telethonin PF09470.10 GAN02743.1 - 0.031 14.2 0.6 0.031 14.2 0.6 2.0 2 1 0 2 2 2 0 Telethonin protein zf-LYAR PF08790.11 GAN02743.1 - 0.044 13.7 1.3 3.4 7.7 0.1 2.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-Di19 PF05605.12 GAN02743.1 - 0.059 13.7 1.8 0.81 10.0 0.2 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.12 GAN02743.1 - 0.16 12.2 5.2 5.2 7.4 0.2 3.1 3 0 0 3 3 3 0 TFIIH C1-like domain zf-H2C2_2 PF13465.6 GAN02743.1 - 0.26 11.8 0.2 0.26 11.8 0.2 3.5 4 0 0 4 4 2 0 Zinc-finger double domain AKAP95 PF04988.12 GAN02743.1 - 1.2 9.4 10.5 4 7.7 0.3 3.3 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) TFIIS_C PF01096.18 GAN02743.1 - 1.3 8.9 11.3 2.3 8.2 0.1 3.2 3 0 0 3 3 2 0 Transcription factor S-II (TFIIS) DUF1644 PF07800.12 GAN02743.1 - 2.2 8.4 12.4 0.12 12.5 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) zf-3CxxC_2 PF17180.4 GAN02743.1 - 3.7 8.4 9.9 0.47 11.2 0.2 3.7 4 0 0 4 4 4 0 Zinc-binding domain OSTbeta PF15048.6 GAN02744.1 - 0.025 14.7 0.8 0.037 14.2 0.8 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein WD40 PF00400.32 GAN02745.1 - 1.9e-47 158.2 17.5 3.5e-10 40.3 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 GAN02745.1 - 1.9e-34 118.7 5.8 7.5e-34 116.8 5.8 2.0 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 GAN02745.1 - 4.3e-11 43.0 0.1 0.064 13.6 0.0 5.3 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN02745.1 - 6.2e-06 25.7 0.9 0.16 11.3 0.0 3.8 3 2 1 4 4 4 3 WD40-like domain Nup160 PF11715.8 GAN02745.1 - 1.4e-05 24.0 5.1 0.58 8.7 0.1 3.8 4 1 0 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 GAN02745.1 - 0.044 13.7 0.0 1.3 8.9 0.0 3.0 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A AFT PF08731.11 GAN02746.1 - 4.1e-05 23.9 0.3 4.1e-05 23.9 0.3 2.4 2 1 0 2 2 2 1 Transcription factor AFT FAR1 PF03101.15 GAN02746.1 - 6.3e-05 23.6 1.1 0.0012 19.5 1.1 2.5 1 1 0 1 1 1 1 FAR1 DNA-binding domain DBD_Tnp_Mut PF03108.15 GAN02746.1 - 0.091 12.8 0.2 0.89 9.6 0.2 2.3 2 0 0 2 2 2 0 MuDR family transposase Sh_2 PF17512.2 GAN02746.1 - 0.56 10.0 6.3 1.1 9.0 1.5 2.2 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein LZ_Tnp_IS66 PF13007.7 GAN02746.1 - 1.6 9.5 4.5 14 6.5 2.8 3.2 3 2 0 3 3 3 0 Transposase C of IS166 homeodomain Peptidase_M41 PF01434.18 GAN02747.1 - 2.8e-67 226.3 0.0 4.2e-67 225.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAN02747.1 - 2.1e-43 147.9 0.0 4.9e-43 146.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN02747.1 - 3.2e-11 42.8 0.4 7.5e-11 41.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 GAN02747.1 - 1.8e-09 37.9 0.1 6.3e-09 36.2 0.1 2.0 1 0 0 1 1 1 1 FtsH Extracellular RuvB_N PF05496.12 GAN02747.1 - 0.0071 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAN02747.1 - 0.0087 15.3 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 GAN02747.1 - 0.0099 16.3 0.8 0.19 12.1 0.2 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAN02747.1 - 0.01 16.1 0.2 0.59 10.4 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 GAN02747.1 - 0.015 15.3 0.0 0.076 13.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAN02747.1 - 0.048 13.4 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 GAN02747.1 - 0.056 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GAN02747.1 - 0.085 13.0 0.2 0.52 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAN02747.1 - 0.12 12.9 0.1 4.3 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain CARD PF00619.21 GAN02747.1 - 0.13 12.3 0.3 0.38 10.8 0.3 1.7 1 0 0 1 1 1 0 Caspase recruitment domain Mg_chelatase PF01078.21 GAN02747.1 - 0.19 11.1 0.3 0.63 9.4 0.2 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAN02747.1 - 0.21 11.9 0.4 0.52 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ELFV_dehydrog_N PF02812.18 GAN02748.1 - 7.8e-60 200.4 0.0 1.4e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 GAN02748.1 - 1.8e-55 188.3 2.7 3.1e-53 181.0 0.2 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAN02748.1 - 0.027 12.0 0.1 0.13 9.7 0.0 2.0 2 1 1 3 3 3 0 Bacterial NAD-glutamate dehydrogenase 2-Hacid_dh_C PF02826.19 GAN02748.1 - 0.041 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1611_N PF17396.2 GAN02748.1 - 0.1 12.9 0.0 0.73 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain tRNA-synt_2 PF00152.20 GAN02749.1 - 4.2e-104 348.0 0.0 7.8e-104 347.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAN02749.1 - 8.5e-09 35.3 0.1 9.5e-08 31.9 0.0 2.8 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Apolipoprotein PF01442.18 GAN02749.1 - 3.8e-08 33.4 37.9 0.00012 22.0 13.1 3.7 2 1 1 3 3 3 3 Apolipoprotein A1/A4/E domain tRNA-synt_2d PF01409.20 GAN02749.1 - 6.5e-05 22.5 0.1 0.00023 20.7 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) GAD PF02938.14 GAN02749.1 - 0.00051 20.2 1.5 0.0025 18.0 0.0 2.9 3 0 0 3 3 3 1 GAD domain YtxH PF12732.7 GAN02749.1 - 0.62 10.6 54.5 1.1 9.8 2.6 7.6 4 2 3 7 7 7 0 YtxH-like protein Prominin PF05478.11 GAN02749.1 - 4.5 5.1 17.5 0.035 12.1 6.6 2.5 2 1 1 3 3 3 0 Prominin NRN1 PF15056.6 GAN02749.1 - 8.2 6.6 6.9 20 5.3 0.0 4.0 3 1 1 4 4 4 0 Neuritin protein family MatP PF06303.12 GAN02750.1 - 0.066 13.8 0.7 0.18 12.4 0.0 2.0 2 0 0 2 2 2 0 MatP N-terminal domain NMO PF03060.15 GAN02751.1 - 1.8e-60 205.1 0.2 2.1e-60 204.9 0.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAN02751.1 - 7.2e-06 25.2 0.0 0.044 12.8 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAN02751.1 - 0.0024 17.0 0.2 0.31 10.0 0.0 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase DHO_dh PF01180.21 GAN02751.1 - 0.0076 15.5 0.0 0.019 14.2 0.0 1.7 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 GAN02751.1 - 0.013 15.0 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Na_Ca_ex PF01699.24 GAN02752.1 - 1.5e-42 145.1 44.0 1.1e-21 77.4 20.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GREB1 PF15782.5 GAN02752.1 - 4.8 4.2 4.9 6.4 3.7 4.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HemY_N PF07219.13 GAN02752.1 - 5.4 7.3 8.6 8 6.7 0.0 3.7 3 0 0 3 3 3 0 HemY protein N-terminus Peptidase_C14 PF00656.22 GAN02753.1 - 1e-63 215.6 0.1 1.4e-63 215.2 0.1 1.2 1 0 0 1 1 1 1 Caspase domain PhyH PF05721.13 GAN02754.1 - 2.6e-11 44.2 0.1 4.1e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Biotin_carb_N PF00289.22 GAN02755.1 - 0.0097 16.5 0.1 0.02 15.4 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain SQS_PSY PF00494.19 GAN02756.1 - 5.6e-55 186.7 0.0 7.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Kelch_6 PF13964.6 GAN02757.1 - 1.3e-06 28.4 4.0 0.02 15.1 0.1 4.8 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAN02757.1 - 1.3e-05 24.6 5.6 0.072 12.7 0.6 4.1 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAN02757.1 - 0.00062 19.6 0.7 2.2 8.4 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 GAN02757.1 - 0.019 15.0 12.3 3.8 7.6 0.4 5.7 5 1 1 6 6 6 0 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN02757.1 - 0.025 14.8 7.1 0.15 12.4 0.2 4.0 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN02757.1 - 0.031 14.3 2.0 10 6.3 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Kelch_6 PF13964.6 GAN02758.1 - 1.6e-10 40.9 3.3 0.0034 17.6 0.0 5.5 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAN02758.1 - 3.5e-10 39.4 0.6 0.11 12.5 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAN02758.1 - 2e-08 33.7 12.6 0.00033 20.2 2.6 5.2 5 1 0 5 5 5 2 Kelch motif PHZA_PHZB PF03284.13 GAN02758.1 - 0.0013 18.3 0.3 0.72 9.5 0.0 2.2 2 0 0 2 2 2 2 Phenazine biosynthesis protein A/B Kelch_4 PF13418.6 GAN02758.1 - 0.028 14.4 11.8 1.1 9.4 0.2 4.9 3 3 0 3 3 3 0 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN02758.1 - 0.17 12.2 9.5 8.1 6.9 0.1 4.6 5 1 1 6 6 6 0 Galactose oxidase, central domain DUF1668 PF07893.13 GAN02758.1 - 0.18 11.1 0.2 0.29 10.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) RNA_pol_L_2 PF13656.6 GAN02759.1 - 1.1e-31 108.3 0.1 1.6e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAN02759.1 - 9.7e-11 40.9 0.0 1.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2722 PF10846.8 GAN02759.1 - 0.095 11.6 3.7 0.091 11.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RPN2_C PF18004.1 GAN02759.1 - 0.71 9.8 6.2 1.1 9.1 6.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4637 PF15470.6 GAN02759.1 - 1.3 8.8 6.7 1.7 8.4 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4611 PF15387.6 GAN02759.1 - 1.7 8.9 10.6 7.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Phage_TAC_4 PF08748.11 GAN02759.1 - 2 8.8 6.4 5.8 7.3 5.6 2.0 1 1 1 2 2 2 0 Phage tail assembly chaperone DNA_pol_phi PF04931.13 GAN02759.1 - 3.7 5.5 10.7 4.1 5.4 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4763 PF15960.5 GAN02759.1 - 9.3 5.5 8.5 9.2 5.5 7.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) TP_methylase PF00590.20 GAN02760.1 - 1e-23 84.4 0.0 1.7e-23 83.7 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Apolipoprotein PF01442.18 GAN02761.1 - 0.00018 21.4 3.6 0.00023 21.1 3.6 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CtIP_N PF10482.9 GAN02761.1 - 0.00024 21.1 1.4 0.0003 20.8 1.4 1.1 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain Spc7 PF08317.11 GAN02761.1 - 0.0031 16.4 0.9 0.0034 16.3 0.9 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4407 PF14362.6 GAN02761.1 - 0.017 14.5 3.9 0.018 14.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 GAN02761.1 - 0.026 13.1 0.6 0.03 12.9 0.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 GAN02761.1 - 0.045 13.0 0.3 0.054 12.7 0.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein HR1 PF02185.16 GAN02761.1 - 0.06 13.5 3.2 0.084 13.0 3.2 1.3 1 0 0 1 1 1 0 Hr1 repeat TMCO5 PF14992.6 GAN02761.1 - 0.064 12.8 1.2 0.067 12.8 0.7 1.3 1 1 0 1 1 1 0 TMCO5 family ApoO PF09769.9 GAN02761.1 - 0.066 13.2 0.1 0.087 12.8 0.1 1.3 1 1 0 1 1 1 0 Apolipoprotein O WXG100 PF06013.12 GAN02761.1 - 0.074 13.3 1.7 0.33 11.2 1.7 1.9 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF883 PF05957.13 GAN02761.1 - 0.087 13.4 8.0 0.11 13.1 6.6 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 GAN02761.1 - 0.15 12.2 0.8 0.19 11.9 0.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 GAN02761.1 - 0.16 12.3 5.0 0.29 11.5 0.8 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4337 PF14235.6 GAN02761.1 - 0.27 11.4 2.8 0.34 11.0 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Spc24 PF08286.11 GAN02761.1 - 0.3 11.4 3.0 0.25 11.6 0.2 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3584 PF12128.8 GAN02761.1 - 0.42 8.1 5.4 0.47 7.9 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KfrA_N PF11740.8 GAN02761.1 - 0.54 11.0 6.1 0.74 10.5 6.1 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term HisKA_3 PF07730.13 GAN02761.1 - 0.82 10.2 4.0 3.4 8.3 0.8 2.1 1 1 1 2 2 2 0 Histidine kinase GrpE PF01025.19 GAN02761.1 - 1.1 9.0 8.4 2.6 7.7 8.4 1.6 1 1 0 1 1 1 0 GrpE DUF1542 PF07564.11 GAN02761.1 - 2.5 8.3 12.8 0.33 11.1 5.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Nup96 PF12110.8 GAN02762.1 - 2.8e-14 52.9 8.6 1.3e-12 47.5 4.5 3.2 2 1 0 2 2 2 2 Nuclear protein 96 MoaE PF02391.17 GAN02763.1 - 4.3e-37 126.9 0.0 4.8e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein CsbD PF05532.12 GAN02764.1 - 1.8e-10 40.6 9.2 4.4e-10 39.3 3.8 2.0 1 1 1 2 2 2 2 CsbD-like Pkinase PF00069.25 GAN02765.1 - 2.5e-69 233.6 0.0 3.4e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02765.1 - 2.5e-31 108.9 0.0 5e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 GAN02765.1 - 0.0068 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Ribosomal_L10 PF00466.20 GAN02766.1 - 5.9e-21 74.5 0.2 8.7e-21 73.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 GAN02766.1 - 1e-20 73.5 0.0 1.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Myb_DNA-bind_6 PF13921.6 GAN02767.1 - 3e-10 40.2 2.8 3.1e-07 30.6 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN02767.1 - 5.7e-10 39.2 2.7 0.00015 21.9 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SUZ PF12752.7 GAN02767.1 - 0.0051 17.5 1.2 1.4 9.7 1.2 2.9 1 1 0 1 1 1 1 SUZ domain Myb_DNA-bind_2 PF08914.11 GAN02767.1 - 0.023 14.9 0.2 6 7.1 0.2 2.7 2 1 0 2 2 2 0 Rap1 Myb domain HATPase_c PF02518.26 GAN02768.1 - 4.1e-29 101.3 0.0 1.2e-28 99.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 GAN02768.1 - 7.2e-26 91.0 0.0 2.7e-24 85.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Peripla_BP_4 PF13407.6 GAN02768.1 - 9.5e-24 84.3 1.2 2.7e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 Periplasmic binding protein domain Pkinase PF00069.25 GAN02768.1 - 3.7e-23 82.2 0.0 1.7e-22 80.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Response_reg PF00072.24 GAN02768.1 - 3.7e-22 78.6 0.1 1.7e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAN02768.1 - 4.8e-17 61.8 0.0 4.8e-17 61.8 0.0 2.2 3 0 0 3 3 1 1 His Kinase A (phospho-acceptor) domain Peripla_BP_1 PF00532.21 GAN02768.1 - 3.2e-08 33.3 0.1 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding proteins and sugar binding domain of LacI family Ephrin_rec_like PF07699.13 GAN02768.1 - 0.00021 21.0 8.6 0.0014 18.4 8.4 2.3 1 1 1 2 2 2 2 Putative ephrin-receptor like PucR PF07905.11 GAN02768.1 - 0.04 14.2 0.0 9 6.6 0.0 2.5 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family NCD3G PF07562.14 GAN02768.1 - 0.041 13.9 7.9 0.012 15.6 2.1 2.4 1 1 2 3 3 3 0 Nine Cysteines Domain of family 3 GPCR UPF0261 PF06792.11 GAN02768.1 - 0.13 11.2 0.0 5 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0261) DUF390 PF04094.14 GAN02768.1 - 0.41 8.9 1.4 0.61 8.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4200 PF13863.6 GAN02768.1 - 2.2 8.7 6.9 0.65 10.4 3.8 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Acetyltransf_7 PF13508.7 GAN02769.1 - 0.086 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN02769.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Sulfate_transp PF00916.20 GAN02770.1 - 1.9e-110 369.2 21.4 2.4e-110 368.9 21.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN02770.1 - 6.2e-07 29.1 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN02770.1 - 2.7e-06 27.8 2.5 2.7e-06 27.8 2.5 3.5 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 GAN02770.1 - 0.14 12.5 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 STAS domain MSP1_C PF07462.11 GAN02771.1 - 2.1 6.9 4.9 1.2 7.7 3.5 1.3 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_L6e PF01159.19 GAN02772.1 - 2.9e-37 127.6 0.3 2.9e-37 127.6 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 GAN02772.1 - 8.6e-11 41.9 1.4 1.5e-10 41.2 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain KOW PF00467.29 GAN02772.1 - 0.0085 16.0 0.8 0.061 13.3 0.1 2.3 2 0 0 2 2 2 1 KOW motif ROS_MUCR PF05443.11 GAN02772.1 - 0.059 13.4 1.0 1.4 9.0 0.3 2.7 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Asp PF00026.23 GAN02773.1 - 5.4e-111 371.0 0.0 6.7e-111 370.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN02773.1 - 2.9e-13 50.4 1.1 6.1e-11 42.9 0.5 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN02773.1 - 0.0038 17.0 0.0 0.0094 15.7 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAN02773.1 - 0.041 14.5 0.0 11 6.8 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease DUF1899 PF08953.11 GAN02774.1 - 1.3e-33 114.6 0.2 2.5e-33 113.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 GAN02774.1 - 2.9e-23 81.5 0.7 5.6e-23 80.6 0.7 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 GAN02774.1 - 1.9e-20 72.8 0.3 3.9e-05 24.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02774.1 - 1.4e-07 31.7 0.3 0.00045 20.5 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SHE3 PF17078.5 GAN02774.1 - 0.0042 16.8 7.8 0.0062 16.3 7.8 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 GAN02774.1 - 0.018 15.2 5.4 0.025 14.7 5.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc29 PF17082.5 GAN02774.1 - 0.096 12.5 1.3 0.15 11.8 1.3 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4094 PF13334.6 GAN02774.1 - 0.17 12.3 0.6 0.35 11.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Tropomyosin_1 PF12718.7 GAN02774.1 - 0.47 10.6 13.6 0.19 11.9 11.1 1.6 2 0 0 2 2 2 0 Tropomyosin like YabA PF06156.13 GAN02774.1 - 4.5 8.0 6.0 7.6 7.2 6.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF4611 PF15387.6 GAN02775.1 - 0.00021 21.5 6.8 0.00025 21.2 6.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Gon7 PF08738.10 GAN02775.1 - 0.011 15.8 7.4 0.011 15.8 7.4 2.1 1 1 0 1 1 1 0 Gon7 family RP-C_C PF11800.8 GAN02775.1 - 0.42 10.7 6.5 0.46 10.5 6.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region zf-RING_2 PF13639.6 GAN02776.1 - 2.7e-11 43.6 6.3 5.1e-11 42.7 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN02776.1 - 3.2e-07 30.1 6.1 6.2e-07 29.2 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN02776.1 - 4.3e-07 30.1 2.8 1.3e-06 28.5 2.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAN02776.1 - 4.9e-07 29.7 1.3 4.9e-07 29.7 1.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAN02776.1 - 6.7e-07 28.9 1.6 6.7e-07 28.9 1.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GAN02776.1 - 1.6e-06 28.0 5.2 3.2e-06 27.0 5.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN02776.1 - 2.7e-06 27.1 7.2 4.9e-06 26.3 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN02776.1 - 0.00014 21.7 6.7 0.00029 20.6 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN02776.1 - 0.00092 19.0 7.7 0.002 18.0 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 GAN02776.1 - 0.021 14.6 3.5 0.047 13.5 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CENP-F_leu_zip PF10473.9 GAN02776.1 - 0.022 14.8 39.8 0.55 10.3 6.5 4.4 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rsa3 PF14615.6 GAN02776.1 - 0.032 13.8 0.2 0.087 12.4 0.2 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 zf-RING_6 PF14835.6 GAN02776.1 - 0.034 14.0 5.1 0.079 12.8 5.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 GAN02776.1 - 0.056 13.5 1.7 0.11 12.5 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_A_type_inc PF04508.12 GAN02776.1 - 0.057 13.3 0.1 0.057 13.3 0.1 3.7 4 0 0 4 4 2 0 Viral A-type inclusion protein repeat NAD_binding_2 PF03446.15 GAN02776.1 - 0.14 12.3 1.1 4.2 7.5 0.1 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C3HC4_4 PF15227.6 GAN02776.1 - 0.18 12.0 8.0 0.49 10.6 8.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING APG6_N PF17675.1 GAN02776.1 - 0.23 12.0 52.6 0.18 12.4 4.0 4.1 1 1 2 4 4 4 0 Apg6 coiled-coil region Fez1 PF06818.15 GAN02776.1 - 0.31 11.5 42.0 0.5 10.8 9.0 3.3 1 1 2 3 3 3 0 Fez1 zf-UDP PF14569.6 GAN02776.1 - 0.65 10.2 4.2 1.3 9.1 4.2 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger HAUS-augmin3 PF14932.6 GAN02776.1 - 0.88 9.1 46.0 0.61 9.6 9.0 4.0 1 1 3 4 4 4 0 HAUS augmin-like complex subunit 3 HOOK PF05622.12 GAN02776.1 - 2.7 6.0 43.5 0.27 9.3 9.7 3.5 1 1 2 3 3 3 0 HOOK protein DUF720 PF05302.11 GAN02776.1 - 5.2 6.9 14.3 0.39 10.6 1.3 3.2 2 2 0 3 3 3 0 Protein of unknown function (DUF720) HIP1_clath_bdg PF16515.5 GAN02776.1 - 6.2 7.5 39.0 0.35 11.5 8.0 4.7 1 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Lipase_3 PF01764.25 GAN02777.1 - 3.5e-35 120.9 0.0 6.4e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAN02777.1 - 0.00052 20.7 0.0 0.0016 19.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 GAN02777.1 - 0.00088 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 GAN02777.1 - 0.00089 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_C47 PF05543.13 GAN02777.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Staphopain peptidase C47 Metallophos PF00149.28 GAN02778.1 - 2.4e-13 51.1 0.1 3.7e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAN02778.1 - 6.5e-06 26.4 0.0 2e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SNARE PF05739.19 GAN02778.1 - 0.00011 22.1 1.4 0.00024 21.0 1.4 1.5 1 0 0 1 1 1 1 SNARE domain ODV-E18 PF10717.9 GAN02778.1 - 0.0063 16.4 0.9 0.013 15.4 0.9 1.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF2140 PF09911.9 GAN02778.1 - 0.0079 15.8 0.3 0.012 15.1 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) EphA2_TM PF14575.6 GAN02778.1 - 0.0093 16.8 0.3 0.019 15.8 0.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4179 PF13786.6 GAN02778.1 - 0.01 16.3 0.1 0.021 15.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF929 PF06053.11 GAN02778.1 - 0.012 14.9 4.8 0.019 14.3 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF3357 PF11837.8 GAN02778.1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) SecG PF03840.14 GAN02778.1 - 0.021 14.9 0.5 0.044 13.9 0.5 1.5 1 0 0 1 1 1 0 Preprotein translocase SecG subunit DUF3671 PF12420.8 GAN02778.1 - 0.056 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function Sigma_reg_N PF13800.6 GAN02778.1 - 0.063 13.6 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SIT PF15330.6 GAN02778.1 - 0.068 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT PRIMA1 PF16101.5 GAN02778.1 - 0.075 13.1 1.0 0.13 12.3 1.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Shisa PF13908.6 GAN02778.1 - 0.077 13.2 0.7 0.13 12.5 0.7 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator UL42 PF17638.2 GAN02778.1 - 0.09 12.8 0.3 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 HCMV UL42 TMEM154 PF15102.6 GAN02778.1 - 0.13 12.2 4.0 0.44 10.4 4.0 2.0 1 1 0 1 1 1 0 TMEM154 protein family Ly49 PF08391.10 GAN02778.1 - 0.13 12.6 0.5 0.28 11.6 0.2 1.7 2 0 0 2 2 1 0 Ly49-like protein, N-terminal region Wzy_C PF04932.15 GAN02778.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase DUF3827 PF12877.7 GAN02778.1 - 0.14 10.5 2.6 0.2 10.0 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) O-ag_pol_Wzy PF14296.6 GAN02778.1 - 0.16 10.6 0.1 0.22 10.2 0.1 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF4834 PF16118.5 GAN02778.1 - 0.18 12.7 0.1 0.38 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PBP1_TM PF14812.6 GAN02778.1 - 0.22 11.9 0.9 0.34 11.3 0.2 1.6 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPPK_C PF12555.8 GAN02778.1 - 0.37 10.9 4.4 0.72 9.9 4.4 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal UPF0258 PF06789.12 GAN02778.1 - 0.47 10.6 4.9 0.81 9.8 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Orf78 PF06024.12 GAN02778.1 - 0.51 10.7 2.5 0.77 10.1 1.7 1.7 1 1 0 1 1 1 0 Orf78 (ac78) FHA PF00498.26 GAN02779.1 - 1.1e-15 57.7 0.1 2.4e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 GAN02779.1 - 2.5e-11 43.1 9.4 4.5e-11 42.3 9.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAN02779.1 - 8.9e-09 35.5 7.9 1.4e-08 34.9 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 GAN02779.1 - 0.00039 20.7 0.0 0.00097 19.4 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 GAN02779.1 - 0.00051 19.8 7.4 0.00088 19.1 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 GAN02779.1 - 0.00065 19.2 0.2 0.00065 19.2 0.2 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-rbx1 PF12678.7 GAN02779.1 - 0.00097 19.4 4.2 0.0029 17.9 4.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAN02779.1 - 0.0035 17.2 8.4 0.0058 16.4 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN02779.1 - 0.0036 17.3 1.2 0.0067 16.5 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAN02779.1 - 0.0091 15.8 5.5 0.02 14.7 5.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAN02779.1 - 0.012 15.6 6.7 0.022 14.7 6.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN02779.1 - 0.021 14.7 3.9 0.032 14.1 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN02779.1 - 0.021 14.8 8.7 0.042 13.9 8.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GAN02779.1 - 0.067 12.8 3.3 0.11 12.1 3.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type YukD PF08817.10 GAN02779.1 - 0.15 12.7 0.0 0.82 10.4 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD PHD PF00628.29 GAN02779.1 - 0.16 11.9 2.7 0.28 11.1 2.7 1.4 1 0 0 1 1 1 0 PHD-finger Adaptin_N PF01602.20 GAN02780.1 - 4.9e-127 424.7 7.3 5.9e-127 424.4 7.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GAN02780.1 - 1.3e-32 112.3 0.0 3.9e-32 110.8 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 GAN02780.1 - 5.6e-11 42.7 0.0 1.6e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain CRAL_TRIO PF00650.20 GAN02781.1 - 7.8e-31 106.9 0.2 1.4e-30 106.2 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN02781.1 - 2.1e-12 47.0 0.2 6.7e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAN02781.1 - 0.029 14.5 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3699 PF12480.8 GAN02781.1 - 0.052 13.7 0.2 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) DUF3198 PF11433.8 GAN02781.1 - 0.097 12.6 0.3 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) SPX PF03105.19 GAN02782.1 - 3.2e-38 132.7 11.5 1.4e-25 91.0 6.8 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 GAN02782.1 - 3.9e-32 111.9 35.3 5.8e-32 111.3 35.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN02782.1 - 1.1e-20 74.0 64.5 1.5e-19 70.3 36.1 2.4 1 1 1 2 2 2 2 Citrate transporter AIG1 PF04548.16 GAN02782.1 - 1e-16 60.9 0.0 1e-16 60.9 0.0 2.1 3 0 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 GAN02782.1 - 1.1e-09 38.4 0.0 2.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAN02782.1 - 0.0018 18.4 4.3 0.58 10.2 0.0 2.9 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 GAN02782.1 - 0.0059 16.5 0.6 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 GAN02782.1 - 0.075 13.6 1.7 0.11 13.0 0.0 2.1 3 0 0 3 3 3 0 ABC transporter HicA_toxin PF07927.12 GAN02782.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, OmpH PF03938.14 GAN02782.1 - 1.3 9.4 10.0 3 8.2 10.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Plasmod_dom_1 PF09715.10 GAN02782.1 - 1.6 8.8 4.1 14 5.8 0.1 3.7 4 0 0 4 4 4 0 Plasmodium protein of unknown function (Plasmod_dom_1) PH PF00169.29 GAN02783.1 - 0.00053 20.5 1.4 0.083 13.4 0.0 3.3 3 0 0 3 3 3 2 PH domain Peptidase_S24 PF00717.23 GAN02784.1 - 3.1e-09 36.7 0.0 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like FAD_binding_1 PF00667.20 GAN02785.1 - 7e-46 156.6 0.0 1.2e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN02785.1 - 1.8e-33 115.8 0.0 4e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAN02785.1 - 1.3e-17 64.4 0.0 8.1e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Vac7 PF12751.7 GAN02786.1 - 1.3e-21 77.5 9.6 3e-20 73.0 0.0 2.8 1 1 3 4 4 4 2 Vacuolar segregation subunit 7 ADH_N PF08240.12 GAN02788.1 - 2.6e-25 88.4 6.8 4.9e-25 87.5 6.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN02788.1 - 2.3e-15 56.7 0.0 4.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAN02788.1 - 0.00085 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAN02788.1 - 0.047 13.0 0.2 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Cys_knot PF00007.22 GAN02788.1 - 0.63 10.4 5.1 0.38 11.1 2.5 1.9 2 1 0 2 2 2 0 Cystine-knot domain ATP-synt_D PF01813.17 GAN02789.1 - 1.9e-73 246.5 4.3 2.5e-73 246.1 4.3 1.2 1 0 0 1 1 1 1 ATP synthase subunit D APG6_N PF17675.1 GAN02789.1 - 0.015 15.8 2.3 0.015 15.8 2.3 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region TSP_NTD PF17804.1 GAN02789.1 - 0.059 13.6 1.2 0.56 10.4 0.0 2.2 1 1 0 2 2 2 0 Tail specific protease N-terminal domain TACC_C PF05010.14 GAN02789.1 - 0.19 11.5 8.4 1.2 8.9 1.2 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mucin15 PF15672.5 GAN02790.1 - 1e-05 25.2 10.2 1.5e-05 24.7 10.2 1.2 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Mucin PF01456.17 GAN02790.1 - 0.00046 20.2 15.4 0.00046 20.2 15.4 2.2 1 1 1 2 2 2 1 Mucin-like glycoprotein SKG6 PF08693.10 GAN02790.1 - 0.0013 18.1 1.1 0.0026 17.2 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 GAN02790.1 - 0.0057 17.1 3.2 0.0057 17.1 3.2 3.0 1 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Beta-APP PF03494.13 GAN02790.1 - 0.044 13.6 2.8 0.091 12.6 2.8 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DDDD PF10161.9 GAN02790.1 - 0.06 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative mitochondrial precursor protein DUF4307 PF14155.6 GAN02790.1 - 0.36 10.7 2.4 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) RAP1 PF07218.11 GAN02790.1 - 1.2 7.4 5.0 1.5 7.0 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tetraspanin PF00335.20 GAN02791.1 - 0.0054 16.5 17.7 0.09 12.5 17.8 2.1 1 1 0 1 1 1 1 Tetraspanin family SelK_SelG PF10961.8 GAN02791.1 - 0.11 13.2 3.1 5.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Bac_export_2 PF01312.19 GAN02791.1 - 1.6 7.9 8.4 0.78 8.9 1.8 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DUF2754 PF10953.8 GAN02791.1 - 1.7 9.0 6.1 5.2 7.4 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2754) DUF4212 PF13937.6 GAN02791.1 - 2.6 8.5 12.7 0.42 11.0 4.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) DUF2569 PF10754.9 GAN02791.1 - 3.7 8.0 17.2 26 5.2 8.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF805 PF05656.14 GAN02791.1 - 9.3 6.7 10.2 2.2 8.7 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF3671 PF12420.8 GAN02792.1 - 0.031 14.4 0.3 0.046 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function MARVEL PF01284.23 GAN02792.1 - 0.073 13.1 2.2 0.12 12.4 2.2 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF5433 PF17498.2 GAN02792.1 - 2 8.7 5.2 0.73 10.1 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5433) SUR7 PF06687.12 GAN02795.1 - 0.0072 16.0 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family XK-related PF09815.9 GAN02795.1 - 0.063 12.3 0.1 0.088 11.9 0.1 1.1 1 0 0 1 1 1 0 XK-related protein QueC PF06508.13 GAN02795.1 - 0.072 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC adh_short PF00106.25 GAN02796.1 - 9.9e-47 158.9 1.5 1.2e-46 158.7 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN02796.1 - 3.4e-36 125.0 0.2 4.1e-36 124.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN02796.1 - 1.3e-12 48.1 0.3 1.8e-12 47.6 0.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAN02796.1 - 5e-07 29.2 0.2 6.9e-07 28.7 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAN02796.1 - 0.00033 20.6 1.5 0.00056 19.9 1.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 GAN02796.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CLP1_P PF16575.5 GAN02796.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Methyltransf_25 PF13649.6 GAN02796.1 - 0.048 14.4 0.1 0.16 12.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.18 GAN02796.1 - 0.11 12.7 1.0 0.41 10.9 0.4 2.1 2 0 0 2 2 2 0 TrkA-N domain ArfGap PF01412.18 GAN02797.1 - 1.5e-36 125.0 0.3 5.2e-36 123.3 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 GAN02797.1 - 1.6e-21 77.1 12.1 3.7e-21 75.9 12.1 1.6 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 GAN02797.1 - 1.5e-14 54.3 0.3 4.3e-14 52.9 0.3 1.8 1 0 0 1 1 1 1 PH domain BAR PF03114.18 GAN02797.1 - 0.015 15.0 8.8 0.052 13.2 8.8 1.9 1 1 0 1 1 1 0 BAR domain DUF29 PF01724.16 GAN02797.1 - 8.6 6.6 7.7 0.34 11.1 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function DUF29 UBX PF00789.20 GAN02798.1 - 5e-13 49.1 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Peroxin-13_N PF04088.13 GAN02798.1 - 0.72 10.1 3.1 46 4.3 0.4 3.2 3 0 0 3 3 3 0 Peroxin 13, N-terminal region SprA-related PF12118.8 GAN02798.1 - 1.9 7.5 9.0 0.094 11.8 3.5 1.5 2 0 0 2 2 2 0 SprA-related family Connexin PF00029.19 GAN02798.1 - 9.6 5.9 6.0 58 3.3 4.4 2.2 2 0 0 2 2 2 0 Connexin Ribosomal_60s PF00428.19 GAN02799.1 - 5.5e-25 87.8 11.6 6.6e-25 87.5 11.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TFIID_30kDa PF03540.13 GAN02799.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit DUF3391 PF11871.8 GAN02799.1 - 0.11 13.1 1.1 0.13 12.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) MAGE_N PF12440.8 GAN02799.1 - 0.27 11.9 7.0 0.34 11.6 7.0 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal zf-C2H2 PF00096.26 GAN02800.1 - 7.7e-06 26.1 8.2 0.22 12.0 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 GAN02800.1 - 4e-05 23.8 3.6 0.15 12.2 0.1 3.4 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 GAN02800.1 - 7.8e-05 23.2 6.6 3.4 8.8 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN02800.1 - 7.1 7.2 15.4 0.12 12.9 1.3 3.4 3 1 0 3 3 3 0 Zinc-finger double domain Fungal_trans PF04082.18 GAN02802.1 - 2.3e-41 141.6 1.6 2.8e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN02802.1 - 1.6e-10 40.9 11.7 1.6e-10 40.9 11.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 GAN02802.1 - 2 8.3 20.2 3.8 7.4 20.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UDPGT PF00201.18 GAN02803.1 - 7.3e-27 94.3 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN02803.1 - 6.3e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Cytochrom_B558a PF05038.13 GAN02804.1 - 0.13 11.8 1.2 0.18 11.4 0.4 1.5 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DAO PF01266.24 GAN02805.1 - 4.2e-40 138.4 0.0 4.8e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAN02805.1 - 7.7e-05 21.9 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAN02805.1 - 0.0033 17.6 0.1 0.011 16.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAN02805.1 - 0.0076 16.8 0.9 0.018 15.6 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAN02805.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAN02805.1 - 0.022 15.2 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 GAN02805.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAN02805.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 GAN02805.1 - 0.13 11.8 0.0 0.71 9.3 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus DEAD PF00270.29 GAN02806.1 - 5.9e-38 130.4 0.0 1.2e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN02806.1 - 1.8e-28 99.1 0.2 1.6e-26 92.8 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN02806.1 - 9.1e-07 29.0 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAN02806.1 - 0.0038 16.6 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Clusterin PF01093.17 GAN02806.1 - 0.083 11.9 3.6 0.51 9.3 0.4 2.2 1 1 1 2 2 2 0 Clusterin FUN14 PF04930.15 GAN02807.1 - 2.2e-25 88.9 2.7 3.5e-25 88.3 2.7 1.3 1 0 0 1 1 1 1 FUN14 family EF-hand_5 PF13202.6 GAN02807.1 - 0.0059 16.0 0.1 0.013 14.9 0.1 1.6 1 0 0 1 1 1 1 EF hand Dockerin_1 PF00404.18 GAN02807.1 - 0.16 12.2 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_1 PF00036.32 GAN02807.1 - 0.24 11.1 0.3 0.59 9.8 0.1 1.9 2 0 0 2 2 2 0 EF hand CUE PF02845.16 GAN02808.1 - 2.5e-07 30.2 0.1 4.7e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF3875 PF12991.7 GAN02808.1 - 0.026 14.5 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) zf-C2H2_4 PF13894.6 GAN02809.1 - 0.0048 17.6 10.2 0.017 15.9 1.1 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger DUF3872 PF12988.7 GAN02809.1 - 0.011 15.6 0.1 0.086 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3872) AviRa PF11599.8 GAN02809.1 - 0.02 14.3 0.0 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 RRNA methyltransferase AviRa zinc_ribbon_6 PF14599.6 GAN02809.1 - 0.049 13.6 0.1 0.7 10.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-ribbon zf-BED PF02892.15 GAN02809.1 - 0.061 13.4 1.6 0.78 9.8 0.3 3.0 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 GAN02809.1 - 0.077 13.5 1.4 0.077 13.5 1.4 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF629 PF04780.12 GAN02809.1 - 0.077 11.5 2.6 1.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-met PF12874.7 GAN02809.1 - 0.099 13.1 4.8 0.12 12.8 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN02809.1 - 1.5 9.2 6.1 0.42 11.0 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ABC_membrane PF00664.23 GAN02810.1 - 9.2e-119 396.1 30.8 9.4e-64 215.7 16.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN02810.1 - 2.2e-70 235.5 0.7 1.1e-34 119.8 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN02810.1 - 4e-14 52.6 4.5 4.8e-07 29.4 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN02810.1 - 5.4e-10 39.7 0.9 0.00012 22.4 0.1 3.7 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 GAN02810.1 - 1.1e-08 34.3 0.4 0.0002 20.3 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 GAN02810.1 - 2.8e-08 33.7 0.2 0.0011 18.7 0.0 3.9 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAN02810.1 - 2.1e-07 31.5 3.0 0.012 16.0 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAN02810.1 - 9.2e-07 28.9 0.3 0.033 14.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAN02810.1 - 1.3e-06 28.1 0.5 0.033 13.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAN02810.1 - 1.8e-06 28.4 2.0 0.25 11.7 0.1 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 GAN02810.1 - 2.2e-06 27.1 0.2 0.023 13.9 0.1 2.4 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 GAN02810.1 - 7.8e-06 25.3 0.2 0.036 13.4 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin Rad17 PF03215.15 GAN02810.1 - 9.5e-06 25.7 0.1 0.012 15.5 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_7 PF12775.7 GAN02810.1 - 4.1e-05 23.2 0.1 0.21 11.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 GAN02810.1 - 8.2e-05 22.9 0.4 0.34 11.1 0.1 3.6 2 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 GAN02810.1 - 0.00011 22.0 0.1 0.23 11.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain Cytidylate_kin PF02224.18 GAN02810.1 - 0.00019 21.2 0.4 0.28 10.9 0.0 2.8 3 0 0 3 3 2 2 Cytidylate kinase SRP54 PF00448.22 GAN02810.1 - 0.00026 20.7 0.0 0.24 11.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain APS_kinase PF01583.20 GAN02810.1 - 0.00031 20.6 0.1 0.14 12.0 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 GAN02810.1 - 0.00035 20.7 0.0 0.78 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAN02810.1 - 0.00041 20.3 0.8 0.21 11.4 0.0 3.5 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 GAN02810.1 - 0.00072 19.9 0.0 1.6 9.1 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.6 GAN02810.1 - 0.00074 20.1 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAN02810.1 - 0.0011 18.7 0.0 0.4 10.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 GAN02810.1 - 0.002 17.6 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 GAN02810.1 - 0.0024 18.0 0.0 1.7 8.8 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAN02810.1 - 0.0034 17.9 6.5 0.87 10.1 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 GAN02810.1 - 0.0037 17.3 0.1 10 6.1 0.0 3.7 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 GAN02810.1 - 0.0063 16.7 9.6 2.2 8.6 1.4 4.7 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit PRK PF00485.18 GAN02810.1 - 0.0084 15.9 0.4 1.3 8.7 0.1 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 GAN02810.1 - 0.011 15.4 0.2 0.53 9.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 GAN02810.1 - 0.012 15.4 0.2 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 GAN02810.1 - 0.016 15.3 0.1 2.9 7.9 0.0 3.7 3 1 1 4 4 3 0 AAA domain DUF87 PF01935.17 GAN02810.1 - 0.017 15.2 5.8 9.3 6.3 0.0 4.1 3 1 1 4 4 4 0 Helicase HerA, central domain Septin PF00735.18 GAN02810.1 - 0.019 14.2 1.0 0.45 9.7 0.0 2.6 3 0 0 3 3 3 0 Septin AAA_19 PF13245.6 GAN02810.1 - 0.041 14.2 0.8 4.4 7.6 0.0 3.2 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAN02810.1 - 0.043 14.2 0.1 17 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain Dala_Dala_lig_N PF01820.21 GAN02810.1 - 0.054 13.9 0.0 20 5.7 0.0 2.6 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus GMC_oxred_N PF00732.19 GAN02810.1 - 0.077 12.4 0.1 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase AAA_25 PF13481.6 GAN02810.1 - 0.079 12.5 0.1 14 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Tape_meas_lam_C PF09718.10 GAN02810.1 - 0.66 10.2 2.7 1.7 8.8 0.4 2.8 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) IstB_IS21 PF01695.17 GAN02810.1 - 2.1 8.0 5.6 24 4.6 0.0 4.0 5 0 0 5 5 4 0 IstB-like ATP binding protein AIG1 PF04548.16 GAN02810.1 - 5.8 6.2 8.8 1.8 7.9 0.1 3.3 4 0 0 4 4 3 0 AIG1 family Zip PF02535.22 GAN02811.1 - 3.4e-61 207.3 11.0 4e-61 207.1 11.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Mntp PF02659.15 GAN02811.1 - 0.079 12.7 6.2 0.41 10.4 0.1 3.2 1 1 1 3 3 3 0 Putative manganese efflux pump YIF1 PF03878.15 GAN02811.1 - 0.16 11.5 1.4 12 5.3 0.6 2.3 2 0 0 2 2 2 0 YIF1 Lyase_1 PF00206.20 GAN02812.1 - 2.2e-121 405.0 0.0 3e-121 404.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAN02812.1 - 9.8e-28 96.4 0.0 2.3e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus B3_4 PF03483.17 GAN02812.1 - 0.044 13.5 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 B3/4 domain DUF4288 PF14119.6 GAN02812.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Haem_degrading PF03928.14 GAN02813.1 - 2.6e-33 114.6 0.0 3.3e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Solute_trans_a PF03619.16 GAN02814.1 - 3.3e-09 36.7 0.7 4.6e-09 36.2 0.7 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CDC27 PF09507.10 GAN02814.1 - 0.088 12.2 4.7 0.12 11.8 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GRIM-19 PF06212.12 GAN02815.1 - 5.3e-30 104.1 0.1 6.2e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein Polysacc_lyase PF14099.6 GAN02816.1 - 0.0001 22.3 0.1 0.00026 20.9 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide lyase Pico_P1A PF02226.16 GAN02816.1 - 1.7 8.7 4.7 0.56 10.3 0.8 2.2 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) bZIP_2 PF07716.15 GAN02817.1 - 7e-07 29.2 7.9 1.3e-06 28.3 7.1 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN02817.1 - 4.1e-05 23.6 6.2 7.8e-05 22.7 6.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor Spc42p PF11544.8 GAN02817.1 - 0.023 14.7 1.0 0.023 14.7 1.0 2.3 2 0 0 2 2 2 0 Spindle pole body component Spc42p Csm1_N PF18504.1 GAN02817.1 - 0.026 14.8 2.5 0.026 14.8 2.5 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain SAND PF01342.21 GAN02817.1 - 0.078 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 SAND domain CAF1-p150_C2 PF15539.6 GAN02817.1 - 0.65 9.4 8.3 0.057 12.9 1.9 2.2 1 1 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term bZIP_Maf PF03131.17 GAN02817.1 - 1.8 9.2 13.9 0.044 14.3 6.0 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.15 GAN02817.1 - 9.7 6.0 7.6 0.35 10.7 0.5 2.2 2 1 1 3 3 3 0 Septum formation initiator Glyco_hydro_45 PF02015.16 GAN02818.1 - 4.6e-81 271.7 21.0 4.6e-81 271.7 21.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 GAN02818.1 - 9.5e-12 44.7 12.9 9.5e-12 44.7 12.9 3.9 4 0 0 4 4 4 2 Fungal cellulose binding domain DAAD PF18752.1 GAN02818.1 - 0.0056 16.6 2.8 0.0075 16.1 2.8 1.1 1 0 0 1 1 1 1 Dictyosteliid AID/APOBEC-like Deaminase Mucin PF01456.17 GAN02818.1 - 0.044 13.8 40.8 0.099 12.6 40.8 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein RIFIN PF02009.16 GAN02818.1 - 3.2 7.6 7.9 4.6 7.1 7.9 1.2 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 GAN02818.1 - 3.9 5.9 8.1 4.9 5.6 8.1 1.1 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 GAN02818.1 - 4.2 5.2 9.7 5 5.0 9.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box-like PF12937.7 GAN02820.1 - 3.7e-07 29.9 0.2 8.6e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN02820.1 - 0.0023 17.8 0.1 0.0075 16.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF1987 PF09345.10 GAN02820.1 - 0.011 15.4 2.4 0.56 9.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1987) LRR_4 PF12799.7 GAN02820.1 - 1.1 9.8 12.4 0.88 10.1 0.3 5.4 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) Catalase PF00199.19 GAN02821.1 - 7.8e-165 548.6 0.0 1.1e-164 548.1 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 GAN02821.1 - 1.2e-33 115.9 0.0 2e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 GAN02821.1 - 7.6e-16 58.1 0.1 1.7e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Bromodomain PF00439.25 GAN02822.1 - 1.8e-41 140.1 3.4 3.6e-21 75.0 0.4 2.8 2 0 0 2 2 2 2 Bromodomain Ank_2 PF12796.7 GAN02822.1 - 4e-12 46.6 0.0 6.8e-07 29.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN02822.1 - 5.4e-06 26.6 0.0 0.0095 16.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN02822.1 - 0.00011 22.3 0.0 0.12 13.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAN02822.1 - 0.0002 21.7 0.0 0.12 12.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAN02822.1 - 0.0013 19.3 0.0 0.0064 17.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AT_hook PF02178.19 GAN02822.1 - 2 8.5 9.1 0.17 11.8 2.9 2.5 2 0 0 2 2 2 0 AT hook motif Peptidase_S8 PF00082.22 GAN02823.1 - 3.7e-51 174.2 0.2 6.7e-51 173.3 0.2 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 GAN02823.1 - 3.5e-11 43.0 0.0 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 PA domain fn3_5 PF06280.12 GAN02823.1 - 1.3e-07 32.3 0.1 2.6e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain Hexapep PF00132.24 GAN02823.1 - 4.9e-07 29.2 14.7 1.2e-05 24.9 3.6 4.1 3 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAN02823.1 - 0.00065 18.8 0.5 0.0011 18.0 0.5 1.3 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 GAN02823.1 - 0.43 10.4 14.6 0.019 14.7 1.8 3.3 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 GAN02824.1 - 3.6e-57 193.7 0.0 4.9e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02824.1 - 4.9e-27 94.8 0.0 6.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAN02824.1 - 0.00096 18.8 0.0 0.036 13.7 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GAN02824.1 - 0.004 16.8 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAN02824.1 - 0.011 15.7 0.0 0.19 11.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN02824.1 - 0.015 14.6 0.0 0.037 13.3 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 GAN02824.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 GAN02824.1 - 0.58 8.3 7.7 0.75 7.9 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.13 GAN02824.1 - 1.3 8.3 4.7 1.9 7.6 4.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SDA1 PF05285.12 GAN02824.1 - 2.1 7.7 6.3 2.8 7.3 6.3 1.2 1 0 0 1 1 1 0 SDA1 EF-hand_6 PF13405.6 GAN02825.1 - 6.7e-05 22.5 0.2 0.00079 19.2 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 GAN02825.1 - 7.9e-05 23.0 0.0 0.00025 21.4 0.0 1.9 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAN02825.1 - 9.9e-05 21.6 0.3 0.00025 20.3 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 GAN02825.1 - 0.00017 20.9 0.7 0.0004 19.7 0.7 1.7 1 0 0 1 1 1 1 EF hand EF_assoc_1 PF08355.12 GAN02825.1 - 0.00063 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated ANAPC3 PF12895.7 GAN02825.1 - 0.0038 17.4 0.1 0.013 15.7 0.0 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAN02825.1 - 0.0039 17.8 0.0 0.0087 16.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Caleosin PF05042.13 GAN02825.1 - 0.0059 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Caleosin related protein Elongin_A PF06881.11 GAN02825.1 - 0.0084 16.6 0.1 0.015 15.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 GAN02825.1 - 0.009 15.9 0.0 0.077 12.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain TPR_1 PF00515.28 GAN02825.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN02825.1 - 0.015 15.4 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_8 PF13833.6 GAN02825.1 - 0.02 14.8 0.2 0.079 12.8 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair F-box-like PF12937.7 GAN02825.1 - 0.088 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like PWI PF01480.17 GAN02827.1 - 3.5e-13 49.7 0.3 8.1e-13 48.5 0.3 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 GAN02827.1 - 3.9e-08 33.0 0.0 7.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UL40 PF10682.9 GAN02827.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Pkinase PF00069.25 GAN02828.1 - 1.2e-65 221.5 0.0 1.5e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02828.1 - 2.1e-25 89.5 0.0 2.8e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN02828.1 - 1.4e-06 27.9 0.0 0.0001 21.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 GAN02828.1 - 0.0014 18.6 0.0 0.0055 16.7 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN02828.1 - 0.0089 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 GAN02828.1 - 0.019 15.1 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 GAN02828.1 - 0.04 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 GAN02828.1 - 0.055 13.1 0.1 0.22 11.1 0.0 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-TRAF PF02176.18 GAN02829.1 - 1.8e-11 44.5 35.5 5e-07 30.3 9.2 4.1 3 1 3 6 6 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 GAN02829.1 - 5.1e-07 29.4 10.7 5.1e-07 29.4 10.7 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN02829.1 - 1.1e-06 28.5 10.1 1.1e-06 28.5 10.1 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAN02829.1 - 1.7e-06 27.8 6.7 1.7e-06 27.8 6.7 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 GAN02829.1 - 2.1e-06 28.1 28.5 0.0007 20.0 6.0 4.2 1 1 2 3 3 3 3 TRAF-like zinc-finger zf-RING_2 PF13639.6 GAN02829.1 - 2.2e-06 27.9 10.9 2.2e-06 27.9 10.9 3.7 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAN02829.1 - 6.9e-06 25.8 11.6 6.9e-06 25.8 11.6 3.8 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN02829.1 - 0.00015 21.6 8.8 0.00015 21.6 8.8 3.3 2 1 0 2 2 1 1 zinc-RING finger domain Sina PF03145.16 GAN02829.1 - 0.00039 20.4 27.3 0.18 11.7 4.4 3.7 1 1 2 3 3 3 2 Seven in absentia protein family zf-rbx1 PF12678.7 GAN02829.1 - 0.00048 20.3 8.9 0.00048 20.3 8.9 4.3 2 2 1 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 GAN02829.1 - 0.0014 18.8 11.7 0.0014 18.8 11.7 2.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING U-box PF04564.15 GAN02829.1 - 0.0018 18.4 0.4 0.033 14.4 0.0 3.0 2 1 0 3 3 2 1 U-box domain zf-Nse PF11789.8 GAN02829.1 - 0.0021 17.9 6.2 0.0021 17.9 6.2 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAN02829.1 - 0.0038 17.1 8.8 0.0038 17.1 8.8 3.3 2 1 1 3 3 1 1 Prokaryotic RING finger family 4 zf-ACC PF17848.1 GAN02829.1 - 0.0047 17.0 12.7 0.026 14.6 0.5 4.5 4 0 0 4 4 4 1 Acetyl-coA carboxylase zinc finger domain zf-RING_10 PF16685.5 GAN02829.1 - 0.023 14.8 3.9 0.023 14.8 3.9 3.3 2 1 1 3 3 2 0 zinc RING finger of MSL2 HALZ PF02183.18 GAN02829.1 - 0.082 13.1 15.7 0.21 11.8 0.6 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper PapD-like PF14874.6 GAN02829.1 - 0.16 12.1 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Flagellar-associated PapD-like THOC7 PF05615.13 GAN02829.1 - 0.27 11.5 9.0 0.048 13.9 1.3 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 Lge1 PF11488.8 GAN02829.1 - 0.35 11.1 8.6 1 9.6 3.9 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF4248 PF14053.6 GAN02829.1 - 0.53 10.3 3.1 15 5.7 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4248) Secretin_N_2 PF07655.13 GAN02829.1 - 0.57 10.7 7.9 0.063 13.8 3.1 1.9 2 0 0 2 2 1 0 Secretin N-terminal domain bZIP_1 PF00170.21 GAN02829.1 - 0.85 9.8 17.1 6.4 7.0 4.6 3.4 2 1 1 3 3 3 0 bZIP transcription factor Uso1_p115_C PF04871.13 GAN02829.1 - 1.7 9.0 12.0 0.67 10.3 1.3 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2968 PF11180.8 GAN02829.1 - 6.8 6.3 12.9 3.4 7.2 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) ZapB PF06005.12 GAN02829.1 - 9.3 6.8 21.7 0.47 10.9 7.4 2.8 2 1 0 2 2 2 0 Cell division protein ZapB Endonuclease_NS PF01223.23 GAN02830.1 - 5e-67 226.0 0.2 5.9e-67 225.8 0.2 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Shugoshin_N PF07558.11 GAN02831.1 - 0.049 13.5 11.0 8.5 6.3 1.0 5.1 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region SNAP-25 PF00835.19 GAN02831.1 - 0.083 13.2 0.1 0.34 11.2 0.1 2.1 1 0 0 1 1 1 0 SNAP-25 family PX PF00787.24 GAN02833.1 - 1.4e-26 92.7 0.0 1.8e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 PX domain TRM PF02005.16 GAN02834.1 - 8.6e-130 433.3 0.0 1.3e-129 432.7 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PTH2 PF01981.16 GAN02834.1 - 5.5e-17 62.1 2.1 8.8e-16 58.3 0.1 2.7 3 0 0 3 3 3 1 Peptidyl-tRNA hydrolase PTH2 Met_10 PF02475.16 GAN02834.1 - 0.0013 18.5 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 GAN02834.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 GAN02834.1 - 0.04 13.6 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 GlutR_dimer PF00745.20 GAN02834.1 - 0.045 14.2 1.3 0.077 13.4 0.2 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Methyltransf_25 PF13649.6 GAN02834.1 - 0.16 12.7 0.0 0.54 11.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DASH_Dad3 PF08656.10 GAN02835.1 - 4.8e-15 55.4 1.7 6.1e-15 55.1 1.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF3332 PF11810.8 GAN02835.1 - 0.021 14.5 2.7 0.023 14.3 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Baculo_IE-1 PF05290.11 GAN02835.1 - 0.11 12.4 0.4 0.16 11.9 0.4 1.3 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DASH_Dad1 PF08649.10 GAN02835.1 - 0.14 12.4 2.4 0.28 11.4 2.2 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad1 DUF948 PF06103.11 GAN02835.1 - 0.17 12.2 1.8 1.3 9.3 1.8 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YABBY PF04690.13 GAN02836.1 - 6.8e-11 43.0 2.0 6.8e-11 43.0 2.0 1.9 1 1 1 2 2 2 1 YABBY protein Ccdc124 PF06244.12 GAN02836.1 - 3.9e-05 24.2 4.8 3.9e-05 24.2 4.8 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 GAN02836.1 - 0.00027 21.3 13.4 0.00038 20.8 13.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN02836.1 - 0.0047 17.5 15.6 0.0058 17.2 15.6 1.1 1 0 0 1 1 1 1 HMG-box domain U1snRNP70_N PF12220.8 GAN02836.1 - 5.3 7.8 16.1 9.3 7.0 16.1 1.5 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Cytomega_UL84 PF06284.11 GAN02836.1 - 9 4.6 7.7 9.6 4.5 7.7 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CDP-OH_P_transf PF01066.21 GAN02837.1 - 4.2e-14 53.1 0.9 4.2e-14 53.1 0.9 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Fasciclin PF02469.22 GAN02839.1 - 8.3e-22 77.8 9.9 2e-11 44.2 2.2 2.4 2 1 0 2 2 2 2 Fasciclin domain DUF961 PF06125.11 GAN02839.1 - 0.055 13.8 0.2 0.42 11.0 0.0 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF961) Ank_2 PF12796.7 GAN02841.1 - 4.3e-08 33.6 0.0 1.3e-05 25.7 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN02841.1 - 7.9e-06 26.3 0.0 0.00028 21.4 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN02841.1 - 1.6e-05 25.1 0.0 0.0064 16.8 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN02841.1 - 0.0014 18.9 0.2 13 6.7 0.0 4.7 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 GAN02841.1 - 0.11 13.0 0.0 4.5 7.9 0.0 3.0 2 2 0 2 2 2 0 Ankyrin repeat IMUP PF15761.5 GAN02841.1 - 0.24 12.1 3.4 0.38 11.5 3.4 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein EMG1 PF03587.14 GAN02842.1 - 7.7e-79 263.9 0.3 9.3e-79 263.6 0.3 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PP2C_C PF07830.13 GAN02842.1 - 0.049 14.1 0.2 0.14 12.7 0.2 1.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Sin3a_C PF16879.5 GAN02843.1 - 9.9e-51 173.1 0.3 2e-50 172.1 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 GAN02844.1 - 2.3e-47 158.9 4.3 3.3e-17 62.4 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAN02844.1 - 1.9e-40 136.9 0.0 1.9e-40 136.9 0.0 3.0 3 0 0 3 3 3 1 Sin3 family co-repressor Sin3a_C PF16879.5 GAN02844.1 - 1.2e-12 48.1 13.3 6.7e-12 45.7 0.1 4.4 4 0 0 4 4 4 2 C-terminal domain of Sin3a protein BUD22 PF09073.10 GAN02844.1 - 7.2e-06 25.6 25.4 7.2e-06 25.6 25.4 3.0 3 0 0 3 3 3 1 BUD22 CDC45 PF02724.14 GAN02844.1 - 0.00035 19.0 20.4 0.00035 19.0 20.4 2.4 2 0 0 2 2 2 1 CDC45-like protein BSP_II PF05432.11 GAN02844.1 - 0.0041 16.9 25.6 0.0041 16.9 25.6 2.6 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 GAN02844.1 - 0.092 11.0 43.3 0.0084 14.4 33.1 3.0 3 0 0 3 3 3 0 Nop14-like family Aa_trans PF01490.18 GAN02845.1 - 3.8e-61 207.0 25.9 4.5e-61 206.8 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 GAN02845.1 - 1e-08 34.5 34.7 3.3e-08 32.8 34.7 1.9 1 1 0 1 1 1 1 Amino acid permease Cytochrom_B_C PF00032.17 GAN02845.1 - 0.15 12.4 6.2 0.34 11.2 0.2 3.4 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD TMEM70 PF06979.12 GAN02845.1 - 1 9.8 4.3 0.84 10.1 1.5 2.3 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex Mito_carr PF00153.27 GAN02846.1 - 6e-60 199.2 3.6 2.9e-23 81.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 GAN02846.1 - 9.4e-05 22.6 0.1 0.43 10.8 0.0 3.3 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PrcB_C PF14343.6 GAN02846.1 - 0.23 11.6 1.4 7.5 6.8 0.1 3.1 3 0 0 3 3 3 0 PrcB C-terminal AD PF09793.9 GAN02847.1 - 2.3e-27 94.9 0.0 4.4e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain LSM PF01423.22 GAN02847.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 LSM domain GET2 PF08690.10 GAN02848.1 - 5.8e-18 65.6 0.6 1.3e-17 64.5 0.6 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 MAP65_ASE1 PF03999.12 GAN02848.1 - 0.15 10.7 2.0 0.17 10.5 2.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ORC6 PF05460.13 GAN02848.1 - 0.61 9.3 2.8 1.1 8.5 2.8 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) L51_S25_CI-B8 PF05047.16 GAN02849.1 - 1.6e-08 34.4 0.2 2.3e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MRP_L53 PF10780.9 GAN02849.1 - 0.00061 19.9 0.1 0.2 11.8 0.0 2.4 2 0 0 2 2 2 2 39S ribosomal protein L53/MRP-L53 NDUFB10 PF10249.9 GAN02851.1 - 6.5e-11 42.8 0.8 7.6e-11 42.6 0.8 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 WD40 PF00400.32 GAN02852.1 - 3.7e-21 75.0 12.1 2.9e-07 31.1 0.0 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02852.1 - 1.7e-05 25.0 0.4 1.3 9.3 0.0 4.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAN02852.1 - 0.00011 22.0 1.3 0.00025 20.9 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN02852.1 - 0.0032 17.3 1.4 0.0032 17.3 1.4 1.9 2 0 0 2 2 2 1 F-box domain eIF2A PF08662.11 GAN02852.1 - 0.017 15.0 0.5 7.5 6.4 0.0 3.6 4 2 0 5 5 5 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 GAN02852.1 - 0.02 13.2 0.0 0.27 9.5 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz TFIIA PF03153.13 GAN02854.1 - 0.33 10.9 63.8 0.44 10.5 63.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 GAN02854.1 - 1.7 7.4 19.3 2.2 7.1 19.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSF_A PF03178.15 GAN02855.1 - 1.8e-91 306.8 0.0 5.8e-91 305.2 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 GAN02855.1 - 3.8e-34 118.2 0.3 6.7e-32 110.7 0.0 3.0 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CAV_VP3 PF04771.12 GAN02855.1 - 0.076 13.2 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Ribosomal_S28e PF01200.18 GAN02856.1 - 1.7e-33 114.4 1.3 2e-33 114.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 GAN02856.1 - 0.041 14.2 0.1 0.06 13.7 0.0 1.4 1 1 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Polysacc_deac_1 PF01522.21 GAN02857.1 - 1.8e-31 108.6 0.1 3.7e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN02857.1 - 1.8e-06 27.4 0.1 4.2e-06 26.2 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 GAN02857.1 - 0.02 14.6 1.7 0.032 13.9 1.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Ribosomal_L39 PF00832.20 GAN02859.1 - 3.5e-19 68.1 13.3 3.5e-19 68.1 13.3 1.8 3 0 0 3 3 3 1 Ribosomal L39 protein SLS PF14611.6 GAN02859.1 - 0.031 14.1 2.6 0.036 13.9 2.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Atg8 PF02991.16 GAN02860.1 - 3.7e-47 158.8 0.5 4.3e-47 158.6 0.5 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GAN02860.1 - 2.5e-05 24.6 0.0 3.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PALP PF00291.25 GAN02861.1 - 4.6e-43 147.7 0.0 6.4e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 GAN02861.1 - 8.7e-18 64.5 0.0 2.4e-09 37.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain GARS_N PF02844.15 GAN02861.1 - 0.15 12.8 0.0 1.7 9.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Actin PF00022.19 GAN02862.1 - 5.5e-31 107.6 0.0 4.9e-30 104.5 0.0 2.1 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 GAN02862.1 - 2.4e-21 76.3 1.3 1.2e-08 34.6 0.1 3.3 3 0 0 3 3 3 3 Putative actin-like family MreB_Mbl PF06723.13 GAN02862.1 - 6e-06 25.3 0.1 0.00019 20.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GAN02862.1 - 0.00026 21.4 0.2 0.0027 18.1 0.2 2.6 2 1 0 2 2 2 1 Cell division protein FtsA CENP-F_leu_zip PF10473.9 GAN02863.1 - 0.00022 21.3 2.1 0.00047 20.2 2.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 GAN02863.1 - 0.0076 16.3 5.7 0.018 15.1 1.9 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) ADIP PF11559.8 GAN02863.1 - 0.018 15.1 9.5 0.018 15.1 9.5 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 GAN02863.1 - 0.033 13.7 6.9 0.13 11.9 3.1 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TMPIT PF07851.13 GAN02863.1 - 0.085 12.1 7.2 0.014 14.6 3.2 1.7 2 0 0 2 2 2 0 TMPIT-like protein PAS_9 PF13426.7 GAN02863.1 - 0.13 12.6 0.2 0.43 10.9 0.1 2.0 2 1 0 2 2 2 0 PAS domain DUF1980 PF09323.10 GAN02863.1 - 0.18 11.7 2.4 0.35 10.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SEP PF08059.13 GAN02863.1 - 0.24 12.0 0.6 0.56 10.8 0.6 1.6 1 0 0 1 1 1 0 SEP domain THOC7 PF05615.13 GAN02863.1 - 0.41 10.9 12.9 0.17 12.1 8.6 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 Prefoldin_2 PF01920.20 GAN02863.1 - 0.43 10.6 14.0 2.9 7.9 8.5 3.5 3 1 0 3 3 3 0 Prefoldin subunit DUF3450 PF11932.8 GAN02863.1 - 0.45 9.8 11.4 0.082 12.2 6.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SOAR PF16533.5 GAN02863.1 - 0.63 10.1 7.7 12 6.0 3.2 2.7 2 0 0 2 2 2 0 STIM1 Orai1-activating region FlxA PF14282.6 GAN02863.1 - 1 9.4 17.5 0.068 13.2 11.6 2.2 2 0 0 2 2 2 0 FlxA-like protein FapA PF03961.13 GAN02863.1 - 3.1 6.3 8.0 0.51 8.9 2.8 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A Fzo_mitofusin PF04799.13 GAN02863.1 - 5.6 6.5 11.1 0.56 9.7 6.0 1.9 2 1 1 3 3 3 0 fzo-like conserved region DUF4665 PF15679.5 GAN02863.1 - 8.8 7.0 12.0 4.6 7.9 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) zf-HC5HC2H_2 PF13832.6 GAN02864.1 - 2.2e-17 63.2 11.6 2.2e-17 63.2 11.6 4.2 4 0 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 GAN02864.1 - 5.3e-15 55.3 0.1 1.5e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 GAN02864.1 - 1.2e-11 44.7 6.3 1.2e-11 44.7 6.3 5.1 4 2 2 6 6 6 1 PHD-like zinc-binding domain PHD PF00628.29 GAN02864.1 - 1.6e-09 37.5 30.2 4.6e-07 29.6 15.1 5.7 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 GAN02864.1 - 1.1e-07 31.3 5.7 1.1e-07 31.3 5.7 5.0 5 0 0 5 5 5 2 PHD-finger ELM2 PF01448.24 GAN02864.1 - 0.00027 21.6 0.0 0.0015 19.3 0.0 2.4 2 1 0 2 2 2 1 ELM2 domain GATA PF00320.27 GAN02864.1 - 0.00053 19.5 0.7 0.00053 19.5 0.7 4.3 4 1 0 4 4 4 1 GATA zinc finger Ytp1 PF10355.9 GAN02865.1 - 3.6e-101 338.0 10.8 3.6e-101 338.0 10.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAN02865.1 - 1e-24 86.3 6.1 1e-24 86.3 6.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Zip PF02535.22 GAN02865.1 - 0.0024 17.1 13.6 0.011 15.0 8.6 2.9 3 1 0 3 3 3 1 ZIP Zinc transporter Cytochrom_B561 PF03188.16 GAN02865.1 - 0.0039 17.3 13.7 0.0039 17.3 13.7 4.7 5 1 0 5 5 5 2 Eukaryotic cytochrome b561 MIEAP PF16026.5 GAN02865.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondria-eating protein Tetraspanin PF00335.20 GAN02865.1 - 3.3 7.4 11.4 0.21 11.3 0.9 3.6 3 2 0 3 3 3 0 Tetraspanin family Pex2_Pex12 PF04757.14 GAN02866.1 - 9.1e-34 117.0 6.8 1.1e-33 116.7 6.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 GAN02866.1 - 8.6e-09 35.1 11.6 1.4e-08 34.4 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN02866.1 - 1.1e-08 35.2 14.1 2e-08 34.4 14.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAN02866.1 - 5.3e-08 32.6 13.6 9.2e-08 31.8 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN02866.1 - 1.6e-07 31.1 12.3 2.6e-07 30.4 12.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAN02866.1 - 3.3e-07 30.0 13.9 5.5e-07 29.3 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN02866.1 - 5.7e-05 23.3 10.2 0.00012 22.3 10.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN02866.1 - 0.00045 20.1 11.0 0.00079 19.3 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAN02866.1 - 0.0005 20.0 12.8 0.0011 18.9 12.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAN02866.1 - 0.017 15.3 12.7 0.036 14.2 12.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAN02866.1 - 0.055 13.3 4.2 0.11 12.3 4.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Peptidase_M56 PF05569.11 GAN02866.1 - 0.1 11.8 0.1 1.3 8.1 0.2 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 zf-RING_11 PF17123.5 GAN02866.1 - 0.19 11.5 2.7 0.53 10.1 2.7 1.8 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 GAN02866.1 - 0.41 10.8 8.5 0.8 9.9 8.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Proteasome PF00227.26 GAN02867.1 - 2.2e-63 213.2 0.5 3.1e-63 212.7 0.5 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAN02867.1 - 5.6e-13 48.3 0.1 1e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ig_GlcNase PF18368.1 GAN02867.1 - 0.048 13.8 0.1 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain BTB_2 PF02214.22 GAN02868.1 - 4.8e-16 58.9 0.0 1.8e-15 57.1 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain Romo1 PF10247.9 GAN02868.1 - 0.16 12.4 0.7 0.33 11.3 0.7 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 NUMOD1 PF07453.13 GAN02869.1 - 0.041 14.2 0.2 0.096 13.0 0.2 1.6 1 0 0 1 1 1 0 NUMOD1 domain HABP4_PAI-RBP1 PF04774.15 GAN02871.1 - 0.0031 18.3 10.7 0.0031 18.3 10.7 3.4 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family F-box-like PF12937.7 GAN02872.1 - 2.6e-10 40.0 0.0 5.9e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN02872.1 - 0.0054 16.6 0.6 0.027 14.3 0.6 2.2 1 1 0 1 1 1 1 F-box domain Saw1 PF11561.8 GAN02872.1 - 0.17 11.4 2.5 0.11 12.0 0.2 1.8 2 0 0 2 2 2 0 Single strand annealing-weakened 1 TFIIE-A_C PF11521.8 GAN02872.1 - 3.7 7.9 13.4 12 6.3 0.5 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha PAS_9 PF13426.7 GAN02873.1 - 1.4e-24 86.3 0.0 3.8e-18 65.7 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 GAN02873.1 - 2e-24 85.7 0.0 6.2e-13 48.9 0.0 4.6 4 1 0 4 4 4 3 PAS fold GATA PF00320.27 GAN02873.1 - 7e-14 51.2 3.2 1.9e-13 49.8 3.2 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 GAN02873.1 - 5.8e-11 42.4 0.1 0.00019 21.4 0.0 3.4 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 GAN02873.1 - 3.3e-09 37.0 0.0 0.0016 18.7 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 GAN02873.1 - 5.9e-09 36.0 0.0 7.6e-07 29.3 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 GAN02873.1 - 0.0016 18.4 0.0 0.056 13.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain DUF4763 PF15960.5 GAN02873.1 - 0.014 14.7 1.1 0.03 13.6 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DZR PF12773.7 GAN02873.1 - 0.14 12.2 0.7 0.45 10.6 0.7 1.9 1 0 0 1 1 1 0 Double zinc ribbon DUF2540 PF10802.8 GAN02873.1 - 0.55 10.4 1.9 7.2 6.8 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) BST2 PF16716.5 GAN02873.1 - 1.6 9.3 5.9 1 10.0 0.6 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Acetyltransf_1 PF00583.25 GAN02875.1 - 1.7e-13 50.8 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN02875.1 - 9.8e-09 35.5 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN02875.1 - 2.9e-06 27.2 0.0 4.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain hnRNP_Q_AcD PF18360.1 GAN02875.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.6 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain GATA PF00320.27 GAN02876.1 - 1.6e-17 62.8 4.9 3.4e-17 61.8 4.9 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 GAN02876.1 - 7.1e-14 51.3 0.9 1.5e-13 50.3 0.9 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 GAN02876.1 - 0.087 12.4 0.9 0.18 11.4 0.9 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding PBP1_TM PF14812.6 GAN02876.1 - 0.087 13.2 0.5 0.41 11.1 0.5 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 GAN02876.1 - 1.1 9.6 7.0 0.15 12.3 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sugar_tr PF00083.24 GAN02877.1 - 2.1e-73 247.7 25.6 2.4e-73 247.5 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN02877.1 - 1.3e-22 80.3 28.4 1.3e-22 80.3 28.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3278 PF11683.8 GAN02877.1 - 0.069 13.2 1.9 0.44 10.6 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) RhoGAP PF00620.27 GAN02878.1 - 1e-27 96.8 0.0 3.2e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 GAN02878.1 - 1.1e-24 87.0 0.0 2.8e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 MyTH4 domain CCDC14 PF15254.6 GAN02878.1 - 5.5 5.5 6.8 8.2 4.9 6.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 F-box-like PF12937.7 GAN02879.1 - 5.4e-05 23.0 0.1 0.00014 21.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN02879.1 - 6.1e-05 22.8 1.4 0.00016 21.5 0.5 2.1 2 0 0 2 2 2 1 F-box domain FKBP26_C PF18046.1 GAN02879.1 - 0.0057 16.7 0.2 0.017 15.2 0.2 2.0 1 0 0 1 1 1 1 FKBP26_C-terminal Gemini_AL1_M PF08283.11 GAN02879.1 - 2.1 8.5 4.4 6.2 7.0 0.3 3.0 3 1 1 4 4 4 0 Geminivirus rep protein central domain Pkinase PF00069.25 GAN02880.1 - 8.1e-69 231.9 0.0 1e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02880.1 - 2.6e-32 112.1 0.0 3.4e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN02880.1 - 2.1e-08 33.9 0.0 1.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAN02880.1 - 0.00019 21.1 0.0 0.61 9.7 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAN02880.1 - 0.005 15.8 0.2 0.019 13.9 0.2 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 GAN02880.1 - 0.01 16.5 0.2 0.034 14.9 0.2 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 GAN02880.1 - 0.022 13.6 0.1 0.055 12.2 0.1 1.7 1 1 0 1 1 1 0 Fungal protein kinase zf-C2H2 PF00096.26 GAN02881.1 - 1.2e-06 28.6 1.4 1.2e-06 28.6 1.4 3.7 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN02881.1 - 6.7e-05 23.4 1.1 6.7e-05 23.4 1.1 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN02881.1 - 0.00015 22.0 10.4 0.0033 17.8 3.4 3.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAN02881.1 - 0.001 19.3 0.3 0.001 19.3 0.3 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding ARS2 PF04959.13 GAN02881.1 - 0.005 17.2 1.1 0.0083 16.5 0.1 1.8 1 1 1 2 2 2 1 Arsenite-resistance protein 2 Zn_ribbon_SprT PF17283.2 GAN02881.1 - 0.0056 16.6 0.5 0.0056 16.6 0.5 1.9 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 GAN02881.1 - 0.012 15.6 0.4 0.012 15.6 0.4 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 GAN02881.1 - 0.046 14.1 0.2 0.046 14.1 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OspE PF02471.17 GAN02881.1 - 0.13 12.5 0.0 2.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Borrelia outer surface protein E Spem1 PF15670.5 GAN02881.1 - 0.45 10.1 6.9 0.59 9.7 6.9 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 E1-E2_ATPase PF00122.20 GAN02882.1 - 1.2e-48 165.0 5.3 1.2e-48 165.0 5.3 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN02882.1 - 2.4e-41 141.5 14.1 2.4e-41 141.5 14.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAN02882.1 - 1.2e-23 84.5 3.4 4.3e-20 72.9 0.1 3.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN02882.1 - 7.6e-19 67.6 0.0 2e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN02882.1 - 6.6e-16 57.8 0.0 2e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN02882.1 - 2.3e-07 30.8 0.5 2.7e-05 24.1 0.3 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN02882.1 - 0.084 13.3 0.0 0.31 11.4 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PAS_3 PF08447.12 GAN02883.1 - 9.9e-17 61.0 0.1 8e-13 48.5 0.0 2.5 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 GAN02883.1 - 3.8e-07 30.1 0.0 0.034 14.2 0.0 2.5 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 GAN02883.1 - 2.2e-06 27.9 0.1 0.0034 17.6 0.0 2.7 1 1 2 3 3 3 2 PAS domain PAS_4 PF08448.10 GAN02883.1 - 0.00041 20.6 0.0 2.1 8.6 0.0 3.2 2 1 1 3 3 3 2 PAS fold PAS_11 PF14598.6 GAN02883.1 - 0.00068 19.7 0.0 0.0019 18.3 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_12 PF18095.1 GAN02883.1 - 0.075 12.7 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain sCache_2 PF17200.4 GAN02883.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Single Cache domain 2 IL17R_fnIII_D2 PF16578.5 GAN02883.1 - 0.11 13.1 0.4 0.2 12.2 0.4 1.4 1 0 0 1 1 1 0 Interleukin 17 receptor D RhoGAP PF00620.27 GAN02884.1 - 2.3e-25 89.2 0.2 1.9e-24 86.2 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain RasGEF_N PF00618.20 GAN02884.1 - 5e-23 81.3 6.0 3.9e-13 49.5 1.8 4.0 2 1 0 2 2 2 2 RasGEF N-terminal motif RasGEF PF00617.19 GAN02884.1 - 1.6e-20 74.1 9.5 4.5e-15 56.3 0.1 4.6 3 1 0 3 3 3 2 RasGEF domain PH_9 PF15410.6 GAN02884.1 - 8.7e-20 71.3 5.3 3.4e-14 53.2 1.8 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 GAN02884.1 - 2.5e-12 47.2 2.0 2.4e-06 28.0 0.1 3.8 2 1 0 3 3 3 2 PH domain Lge1 PF11488.8 GAN02884.1 - 0.032 14.4 2.2 0.15 12.3 2.2 2.2 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Pribosyltran_N PF13793.6 GAN02885.1 - 4.5e-44 149.1 0.7 7.8e-42 141.9 0.1 2.6 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAN02885.1 - 2.1e-41 142.0 2.6 5.4e-40 137.4 2.6 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAN02885.1 - 1.6e-07 31.0 0.3 1.1e-06 28.3 0.2 2.3 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Mcp5_PH PF12814.7 GAN02886.1 - 2.4e-37 127.8 0.0 8.1e-37 126.0 0.0 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 GAN02886.1 - 3.4e-05 24.3 0.0 8.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Filament PF00038.21 GAN02886.1 - 0.094 12.3 41.7 0.0057 16.3 23.2 3.7 3 0 0 3 3 3 0 Intermediate filament protein Scaffolding_pro PF11418.8 GAN02886.1 - 2.8 8.6 10.6 31 5.2 0.8 3.3 1 1 1 2 2 2 0 Phi29 scaffolding protein Nucleoporin_FG2 PF15967.5 GAN02887.1 - 2.4e-06 26.4 56.1 2.4e-06 26.4 56.1 4.9 1 1 2 3 3 3 1 Nucleoporin FG repeated region ArAE_1_C PF11728.8 GAN02887.1 - 0.068 13.2 9.9 1.1 9.3 1.7 3.2 2 1 1 3 3 3 0 Putative aromatic acid exporter C-terminal domain DUF4318 PF14201.6 GAN02887.1 - 0.077 13.5 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) Sec66 PF09802.9 GAN02887.1 - 0.082 12.5 0.4 0.18 11.4 0.4 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF4407 PF14362.6 GAN02887.1 - 1.9 7.8 4.1 0.39 10.0 0.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GAN02887.1 - 4.9 6.6 7.5 9.9 5.6 7.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit ANAPC4_WD40 PF12894.7 GAN02889.1 - 8.2e-06 26.0 0.0 0.022 15.0 0.0 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN02889.1 - 0.00062 20.5 0.2 0.054 14.4 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat NrfD_2 PF14589.6 GAN02893.1 - 0.045 13.7 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 Polysulfide reductase Prefoldin_2 PF01920.20 GAN02895.1 - 7.3e-25 87.0 7.1 8.3e-25 86.8 7.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit ATPase PF06745.13 GAN02895.1 - 0.0025 17.2 0.1 0.0036 16.7 0.1 1.3 1 1 0 1 1 1 1 KaiC TPR_MLP1_2 PF07926.12 GAN02895.1 - 0.011 15.8 0.5 0.011 15.8 0.5 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 GAN02895.1 - 0.013 15.8 4.1 0.17 12.2 0.4 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2935 PF11155.8 GAN02895.1 - 0.014 15.8 0.9 0.017 15.4 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Prefoldin_3 PF13758.6 GAN02895.1 - 0.033 14.2 1.7 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 GAN02895.1 - 0.037 14.0 0.9 0.037 14.0 0.9 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 GAN02895.1 - 0.039 14.2 7.1 0.94 9.7 7.2 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5595 PF18077.1 GAN02895.1 - 0.046 13.8 7.4 0.89 9.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) FapA PF03961.13 GAN02895.1 - 0.05 12.2 4.0 0.061 11.9 4.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dad3 PF08656.10 GAN02895.1 - 0.076 13.1 3.7 0.047 13.8 1.0 1.9 1 1 1 2 2 2 0 DASH complex subunit Dad3 SHE3 PF17078.5 GAN02895.1 - 0.077 12.7 5.2 0.56 9.9 5.2 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF5457 PF17540.2 GAN02895.1 - 0.093 12.8 0.4 0.093 12.8 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5457) ZnuA PF01297.17 GAN02895.1 - 0.1 12.0 2.1 0.11 11.9 0.3 1.7 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic IFT57 PF10498.9 GAN02895.1 - 0.2 10.6 8.3 1.7 7.5 0.3 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 GAS PF13851.6 GAN02895.1 - 0.21 10.9 9.4 0.78 9.1 0.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 GAN02895.1 - 0.33 11.0 6.1 4.2 7.4 1.1 2.0 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3810 PF12725.7 GAN02895.1 - 0.41 10.0 2.9 2.4 7.4 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3810) bZIP_1 PF00170.21 GAN02895.1 - 0.42 10.7 4.4 0.28 11.3 1.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor SlyX PF04102.12 GAN02895.1 - 0.44 11.2 5.8 4.6 7.9 0.2 2.4 2 1 0 2 2 2 0 SlyX DASH_Spc34 PF08657.10 GAN02895.1 - 0.56 10.0 9.0 0.29 10.9 2.2 2.0 1 1 0 2 2 2 0 DASH complex subunit Spc34 DivIC PF04977.15 GAN02895.1 - 0.56 10.0 7.3 0.71 9.7 2.6 2.2 2 0 0 2 2 2 0 Septum formation initiator OmpH PF03938.14 GAN02895.1 - 0.87 9.9 11.8 4.2 7.7 11.8 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 GAN02895.1 - 1.1 9.8 8.6 1.6 9.2 1.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 GAN02895.1 - 7.1 7.2 11.6 96 3.5 11.6 2.1 1 1 0 1 1 1 0 Cell division protein ZapB Sod_Cu PF00080.20 GAN02896.1 - 5.5e-34 117.4 2.8 1.2e-33 116.3 2.8 1.6 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 GAN02896.1 - 5.5e-11 42.7 0.9 1.7e-10 41.2 0.1 2.3 2 0 0 2 2 2 1 Heavy-metal-associated domain Inhibitor_I9 PF05922.16 GAN02896.1 - 3.9e-07 30.7 0.4 8e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1939 PF09154.10 GAN02896.1 - 0.067 13.4 0.7 0.18 12.0 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) PID PF00640.23 GAN02897.1 - 0.051 13.6 0.1 0.55 10.3 0.0 2.5 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Ion_trans PF00520.31 GAN02898.1 - 2.2e-06 27.1 7.9 4.8e-06 26.0 8.0 1.5 1 1 0 1 1 1 1 Ion transport protein Cytochrom_B561 PF03188.16 GAN02899.1 - 1.8e-17 63.8 7.9 1.8e-17 63.8 7.9 2.9 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 GAN02899.1 - 0.0014 18.4 15.5 0.0061 16.3 2.6 3.5 2 2 1 3 3 3 2 Domain of unknown function (DUF2427) Sec20 PF03908.13 GAN02899.1 - 0.18 11.7 0.3 0.18 11.7 0.3 2.0 2 0 0 2 2 2 0 Sec20 CBFD_NFYB_HMF PF00808.23 GAN02900.1 - 6.7e-16 58.3 1.1 9.1e-16 57.9 1.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAN02900.1 - 7.2e-05 23.2 0.7 0.0001 22.6 0.7 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 EST1 PF10374.9 GAN02901.1 - 0.064 13.9 0.7 0.097 13.3 0.7 1.3 1 0 0 1 1 1 0 Telomerase activating protein Est1 ResIII PF04851.15 GAN02902.1 - 3e-15 56.7 1.6 1.1e-14 54.8 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit BAG PF02179.16 GAN02902.1 - 1.7e-14 54.0 0.9 5.8e-14 52.3 0.9 2.0 1 0 0 1 1 1 1 BAG domain Helicase_C PF00271.31 GAN02902.1 - 1.9e-13 50.7 0.1 8.6e-13 48.6 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 GAN02902.1 - 8.6e-06 25.6 0.1 8.6e-06 25.6 0.1 2.2 3 0 0 3 3 3 1 SWI2/SNF2 ATPase DEAD PF00270.29 GAN02902.1 - 4.7e-05 23.2 0.3 0.00031 20.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 GAN02902.1 - 7.1e-05 22.2 0.1 0.00026 20.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SelP_N PF04592.14 GAN02903.1 - 0.0016 17.9 16.2 0.0027 17.2 16.2 1.3 1 0 0 1 1 1 1 Selenoprotein P, N terminal region DUF3452 PF11934.8 GAN02903.1 - 0.093 12.3 3.8 0.037 13.6 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) PH PF00169.29 GAN02905.1 - 4.2e-08 33.7 0.5 2.6e-06 27.9 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 GAN02905.1 - 0.0019 18.6 0.0 0.0059 17.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain WD40 PF00400.32 GAN02906.1 - 7.1e-14 52.0 2.1 0.2 12.6 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02906.1 - 0.00014 22.1 0.6 14 6.1 0.0 5.3 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ATP_synt_H PF05493.13 GAN02907.1 - 1.1e-20 73.8 6.2 1.5e-20 73.4 6.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit H YibE_F PF07907.11 GAN02907.1 - 0.031 13.8 1.9 0.035 13.6 1.9 1.0 1 0 0 1 1 1 0 YibE/F-like protein ARL6IP6 PF15062.6 GAN02907.1 - 0.069 13.3 0.1 0.069 13.3 0.1 1.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix TssN PF17555.2 GAN02907.1 - 0.086 12.2 1.2 0.1 12.0 1.2 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN VIT1 PF01988.19 GAN02907.1 - 0.55 10.1 2.2 0.57 10.0 2.2 1.0 1 0 0 1 1 1 0 VIT family FixQ PF05545.11 GAN02907.1 - 0.74 9.8 5.4 0.51 10.4 0.3 2.1 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ABC_membrane PF00664.23 GAN02908.1 - 2.5e-50 171.7 6.3 3.5e-50 171.2 6.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAN02908.1 - 5e-36 124.2 0.0 1e-35 123.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAN02908.1 - 2.9e-07 30.2 0.7 2.6e-05 23.8 0.0 2.6 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_membrane_2 PF06472.15 GAN02908.1 - 3.2e-06 26.8 0.1 5.7e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 APS_kinase PF01583.20 GAN02908.1 - 0.00091 19.2 0.0 0.0031 17.4 0.0 1.9 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 GAN02908.1 - 0.00095 19.4 0.3 0.013 15.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN02908.1 - 0.0029 18.0 0.0 0.0079 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 GAN02908.1 - 0.0029 16.9 0.0 0.0074 15.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 GAN02908.1 - 0.0074 16.8 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAN02908.1 - 0.0083 16.5 0.5 0.25 11.8 0.5 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAN02908.1 - 0.011 15.3 0.1 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAN02908.1 - 0.013 15.2 0.1 0.031 14.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAN02908.1 - 0.018 14.8 0.1 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 GAN02908.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 GAN02908.1 - 0.026 14.5 0.0 0.53 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 GAN02908.1 - 0.026 13.3 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 GAN02908.1 - 0.029 14.5 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 GAN02908.1 - 0.081 12.7 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 GAN02908.1 - 0.083 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 GAN02908.1 - 0.094 13.0 0.4 1 9.6 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 GAN02908.1 - 0.11 12.1 0.1 2.8 7.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAN02908.1 - 0.17 11.6 0.0 0.49 10.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol_A_exo1 PF01612.20 GAN02909.1 - 6.7e-11 42.2 0.1 1.6e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease Methyltransf_25 PF13649.6 GAN02910.1 - 1.6e-11 44.8 0.0 3.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN02910.1 - 4.4e-10 40.1 0.0 1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN02910.1 - 3.5e-06 26.9 0.0 8.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN02910.1 - 9.2e-06 25.5 0.0 0.00012 21.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAN02910.1 - 2.7e-05 24.1 0.0 5.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 GAN02910.1 - 9.3e-05 21.9 0.0 0.00053 19.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family WD40 PF00400.32 GAN02910.1 - 0.00019 22.2 0.0 3.1 8.8 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02910.1 - 0.00063 20.0 0.0 1 9.7 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_12 PF08242.12 GAN02910.1 - 0.0032 18.2 0.1 0.13 13.0 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Lipase3_N PF03893.16 GAN02910.1 - 0.013 15.5 0.1 0.42 10.7 0.0 3.1 4 0 0 4 4 4 0 Lipase 3 N-terminal region WD40_like PF17005.5 GAN02910.1 - 0.032 13.6 0.2 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 WD40-like domain 4HBT PF03061.22 GAN02911.1 - 3.7e-10 40.0 0.0 5.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 GAN02911.1 - 7.4e-07 29.7 0.0 9.4e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 GAN02911.1 - 4.8e-06 26.0 0.0 5.1e-05 22.7 0.3 1.9 1 1 1 2 2 2 1 Acyl-ACP thioesterase DUF5390 PF17365.2 GAN02911.1 - 0.012 15.8 0.5 0.017 15.4 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5390) TRAM_LAG1_CLN8 PF03798.16 GAN02912.1 - 2.5e-40 138.3 21.5 2.5e-40 138.3 21.5 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAN02912.1 - 2.6e-15 55.8 1.1 2.6e-15 55.8 1.1 2.6 4 0 0 4 4 4 1 TRAM1-like protein Methyltransf_11 PF08241.12 GAN02913.1 - 0.00015 22.3 0.1 0.002 18.7 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 GAN02913.1 - 0.007 16.1 2.0 0.022 14.5 0.1 2.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_18 PF12847.7 GAN02913.1 - 0.013 15.4 2.7 0.12 12.3 0.1 3.7 2 0 0 2 2 2 0 Methyltransferase domain BCL_N PF04714.13 GAN02913.1 - 0.11 12.6 0.0 0.8 9.8 0.0 2.7 1 0 0 1 1 1 0 BCL7, N-terminal conserver region DUF4179 PF13786.6 GAN02913.1 - 0.14 12.6 1.0 0.89 10.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Methyltransf_12 PF08242.12 GAN02913.1 - 0.75 10.6 0.0 0.75 10.6 0.0 5.1 5 1 1 6 6 6 0 Methyltransferase domain DDE_1 PF03184.19 GAN02914.1 - 1.6e-12 47.4 0.3 7.1e-12 45.3 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 GAN02914.1 - 7.3e-05 22.4 1.1 0.00016 21.3 1.1 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 GAN02914.1 - 0.0045 17.0 0.1 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SET_assoc PF11767.8 GAN02914.1 - 0.062 12.9 0.1 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated HTH_7 PF02796.15 GAN02915.1 - 0.0074 16.3 0.2 0.051 13.7 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase UCH PF00443.29 GAN02916.1 - 3.6e-36 125.0 0.0 6.2e-36 124.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN02916.1 - 1.1e-11 45.0 0.9 3.9e-11 43.1 0.9 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase STAT_int PF02865.17 GAN02916.1 - 0.14 12.6 0.3 2.1 8.8 0.0 2.5 2 1 1 3 3 3 0 STAT protein, protein interaction domain Peptidase_C98 PF15499.6 GAN02916.1 - 0.29 10.5 2.6 30 4.0 0.0 3.3 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase XPG_I_2 PF12813.7 GAN02917.1 - 0.085 12.3 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 XPG domain containing Kelch_6 PF13964.6 GAN02918.1 - 2.9e-07 30.6 1.8 0.94 9.9 0.0 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GAN02918.1 - 7.7e-05 22.6 1.1 0.23 11.5 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 GAN02918.1 - 0.0089 16.0 9.4 0.7 9.9 0.0 5.0 6 0 0 6 6 6 2 Galactose oxidase, central domain RIFIN PF02009.16 GAN02918.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 GAN02918.1 - 0.053 13.4 0.7 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family LapA_dom PF06305.11 GAN02918.1 - 0.11 12.3 2.5 0.068 13.0 0.5 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Kelch_1 PF01344.25 GAN02918.1 - 0.2 11.3 2.1 16 5.1 0.1 4.0 4 0 0 4 4 4 0 Kelch motif PTCB-BRCT PF12738.7 GAN02919.1 - 5.1e-23 80.8 0.0 5.3e-09 35.9 0.0 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 GAN02919.1 - 8.1e-23 80.6 0.0 1.3e-08 35.1 0.0 4.9 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAN02919.1 - 1.9e-16 60.2 0.1 0.00093 19.6 0.0 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GAN02919.1 - 0.01 16.1 0.0 4.8 7.5 0.0 3.8 5 0 0 5 5 5 0 DNA ligase 3 BRCT domain C1_2 PF03107.16 GAN02919.1 - 2.8 8.3 4.7 5.3 7.4 0.8 2.5 2 0 0 2 2 2 0 C1 domain Pkinase PF00069.25 GAN02920.1 - 3.3e-23 82.4 0.0 4.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN02920.1 - 1.6e-10 40.7 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN02920.1 - 7e-08 31.7 0.0 8.8e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sugar_tr PF00083.24 GAN02921.1 - 5.3e-93 312.3 23.4 6.4e-93 312.1 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN02921.1 - 6.9e-29 100.9 54.3 1.9e-26 92.8 25.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.22 GAN02923.1 - 4.5e-64 214.9 0.8 6.7e-64 214.4 0.8 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN02923.1 - 1.9e-35 121.7 0.1 3.9e-35 120.7 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN02923.1 - 1.4e-16 60.4 0.2 2.4e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cellulase PF00150.18 GAN02923.1 - 7e-11 42.1 0.7 1.5e-10 40.9 0.1 2.0 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) GTP_EFTU PF00009.27 GAN02923.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN02923.1 - 5.3e-05 23.2 0.2 0.2 11.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAN02923.1 - 6.8e-05 22.3 0.2 0.0001 21.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN02923.1 - 0.00036 20.6 0.0 0.00073 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAN02923.1 - 0.00055 19.4 0.2 0.0009 18.7 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAN02923.1 - 0.025 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 GAN02923.1 - 0.07 12.7 0.2 0.3 10.6 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 GAN02923.1 - 0.12 11.6 0.1 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Septin AAA PF00004.29 GAN02923.1 - 0.15 12.5 0.2 4.4 7.7 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAN02923.1 - 0.16 11.7 0.2 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Methyltransf_25 PF13649.6 GAN02924.1 - 1e-09 39.0 0.0 1e-08 35.8 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN02924.1 - 9.9e-08 32.0 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN02924.1 - 3.2e-07 30.9 0.0 8.2e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN02924.1 - 2.4e-06 27.4 0.0 1.6e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Globin PF00042.22 GAN02924.1 - 2.7e-05 24.7 0.6 0.066 13.8 0.0 3.4 3 0 0 3 3 3 2 Globin Ubie_methyltran PF01209.18 GAN02924.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 GAN02924.1 - 0.019 13.5 0.0 0.067 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acetyltransf_10 PF13673.7 GAN02925.1 - 3.8e-13 49.5 0.0 6.5e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN02925.1 - 5.5e-12 46.0 0.0 7.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN02925.1 - 1.1e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 GAN02925.1 - 0.0012 19.5 0.0 0.004 17.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAN02925.1 - 0.006 16.7 0.0 0.035 14.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN02925.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein GH97_C PF14509.6 GAN02925.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation ArfGap PF01412.18 GAN02926.1 - 5.3e-23 81.3 0.0 1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 GAN02926.1 - 0.0043 16.5 0.3 0.0076 15.7 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIA PF03153.13 GAN02927.1 - 1.7e-79 268.8 15.1 1.8e-77 262.1 15.1 2.0 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MAGI_u5 PF16666.5 GAN02927.1 - 0.018 15.2 9.2 0.018 15.2 9.2 1.8 2 0 0 2 2 2 0 Unstructured region on MAGI PBP1_TM PF14812.6 GAN02927.1 - 0.35 11.3 0.1 0.35 11.3 0.1 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CBFD_NFYB_HMF PF00808.23 GAN02929.1 - 4.3e-30 103.8 1.0 6.1e-30 103.3 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAN02929.1 - 3.5e-06 27.4 0.1 3.5e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAN02929.1 - 0.00019 21.5 0.0 0.00032 20.8 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 GAN02929.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 GAN02929.1 - 0.029 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-X PF09415.10 GAN02929.1 - 0.089 13.1 1.3 0.13 12.6 0.4 1.7 1 1 0 1 1 1 0 CENP-S associating Centromere protein X TFIID_20kDa PF03847.13 GAN02929.1 - 0.14 12.7 0.1 0.68 10.5 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DUF4770 PF15994.5 GAN02929.1 - 0.14 12.3 3.6 0.66 10.2 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) DUF3712 PF12505.8 GAN02931.1 - 1.2e-30 106.3 17.0 1.8e-15 57.3 3.4 4.3 4 0 0 4 4 4 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAN02931.1 - 4.6e-06 27.1 1.7 0.94 10.1 0.0 5.0 5 0 0 5 5 5 3 Late embryogenesis abundant protein DUF3712 PF12505.8 GAN02932.1 - 7e-10 39.2 3.0 1e-09 38.7 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1356 PF07092.12 GAN02932.1 - 0.052 12.8 2.3 0.36 10.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Tmemb_9 PF05434.11 GAN02932.1 - 0.13 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 TMEM9 Dymeclin PF09742.9 GAN02933.1 - 3.2e-107 359.5 33.8 3.9e-107 359.2 33.8 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 GAN02933.1 - 8.5e-12 44.1 23.3 2.7e-11 42.4 16.8 2.4 2 1 0 2 2 2 2 High-temperature-induced dauer-formation protein Kinesin PF00225.23 GAN02934.1 - 6.2e-86 288.3 1.1 6.2e-86 288.3 1.1 3.2 2 2 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN02934.1 - 3.7e-19 69.1 1.4 1.6e-18 67.0 0.1 2.8 2 0 0 2 2 2 1 Microtubule binding TFA2_Winged_2 PF18121.1 GAN02934.1 - 0.076 12.7 3.1 0.86 9.3 1.5 3.7 4 0 0 4 4 4 0 TFA2 Winged helix domain 2 IF-2B PF01008.17 GAN02935.1 - 0.02 14.1 0.1 0.027 13.7 0.1 1.3 1 1 0 1 1 1 0 Initiation factor 2 subunit family Aminotran_1_2 PF00155.21 GAN02936.1 - 4.5e-86 289.3 0.0 5.1e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Mg-por_mtran_C PF07109.11 GAN02937.1 - 0.21 12.0 0.5 0.45 10.9 0.2 1.7 1 1 1 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus NIF PF03031.18 GAN02938.1 - 2.1e-28 99.1 0.6 2.7e-27 95.5 0.1 2.6 3 0 0 3 3 3 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 GAN02938.1 - 9.3e-10 38.3 0.1 2.4e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 GAN02938.1 - 0.00056 20.2 0.2 0.0017 18.7 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAN02938.1 - 0.0047 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF1542 PF07564.11 GAN02938.1 - 7.5 6.7 7.7 0.39 10.9 1.8 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Cation_ATPase_C PF00689.21 GAN02939.1 - 1.3e-45 155.3 15.5 1.8e-45 154.9 10.9 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAN02939.1 - 4.2e-40 137.2 1.6 4.2e-40 137.2 1.6 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAN02939.1 - 1.6e-22 79.4 0.0 3.9e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN02939.1 - 2.8e-18 67.0 0.2 7e-18 65.7 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN02939.1 - 7.5e-12 44.8 0.0 1.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN02939.1 - 0.0021 17.9 0.3 0.0021 17.9 0.3 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase B12D PF06522.11 GAN02941.1 - 4.6e-22 77.6 0.0 6e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit NPBW PF15180.6 GAN02941.1 - 0.023 14.6 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Neuropeptides B and W Voltage_CLC PF00654.20 GAN02941.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel MFS_1 PF07690.16 GAN02943.1 - 5.9e-31 107.7 35.1 5.4e-27 94.6 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN02943.1 - 1.5e-09 37.3 8.1 1.5e-09 37.3 8.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAN02943.1 - 0.00022 19.8 0.7 0.00053 18.5 0.7 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Recep_L_domain PF01030.24 GAN02944.1 - 1.1e-09 38.4 1.4 0.00037 20.6 0.0 3.6 1 1 2 3 3 3 3 Receptor L domain LRR_4 PF12799.7 GAN02944.1 - 0.17 12.3 1.3 6.9 7.2 0.0 3.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) SWIB PF02201.18 GAN02946.1 - 1.2e-27 95.5 0.1 2.4e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Dus PF01207.17 GAN02947.1 - 4.1e-56 190.3 0.1 1e-55 189.0 0.1 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 GAN02947.1 - 0.013 14.5 0.0 0.052 12.6 0.0 1.8 1 1 1 2 2 2 0 FMN-dependent dehydrogenase Nbas_N PF15492.6 GAN02947.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal MMS1_N PF10433.9 GAN02949.1 - 2.4e-85 287.0 0.2 5.3e-85 285.9 0.1 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAN02949.1 - 9e-59 199.4 0.2 5.6e-58 196.8 0.4 2.2 2 0 0 2 2 2 1 CPSF A subunit region ROQ_II PF18386.1 GAN02949.1 - 0.17 11.7 0.0 0.53 10.2 0.0 1.8 1 0 0 1 1 1 0 Roquin II domain FYVE PF01363.21 GAN02950.1 - 8.5e-11 41.8 12.7 8.5e-11 41.8 12.7 2.7 2 1 0 2 2 2 1 FYVE zinc finger DnaJ PF00226.31 GAN02952.1 - 5.5e-21 74.5 1.0 1.1e-20 73.6 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain ERG4_ERG24 PF01222.17 GAN02953.1 - 6.2e-148 493.1 6.9 9.5e-148 492.5 6.9 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAN02953.1 - 0.00014 21.4 0.2 0.00046 19.8 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MetOD1 PF18546.1 GAN02953.1 - 0.071 13.1 0.5 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 Metanogen output domain 1 DUF4175 PF13779.6 GAN02953.1 - 0.15 9.9 1.4 0.31 8.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1765 PF08578.10 GAN02953.1 - 0.38 11.2 4.7 5.1 7.6 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1765) ubiquitin PF00240.23 GAN02954.1 - 0.02 14.7 0.5 0.049 13.4 0.5 1.7 1 1 0 1 1 1 0 Ubiquitin family EIIA-man PF03610.16 GAN02954.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component SPOUT_MTase_2 PF14419.6 GAN02954.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP IBN_N PF03810.19 GAN02955.1 - 0.043 13.7 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 Importin-beta N-terminal domain CRM1_C PF08767.11 GAN02956.1 - 2.5e-120 401.5 0.6 2.5e-120 401.5 0.6 2.5 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 GAN02956.1 - 4.9e-40 137.0 8.5 9e-40 136.1 5.2 3.2 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAN02956.1 - 5.5e-31 106.0 4.2 5.5e-31 106.0 4.2 2.8 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAN02956.1 - 2.5e-30 104.4 4.3 2.8e-29 101.0 1.3 3.7 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 GAN02956.1 - 1.5e-20 72.4 1.1 1.5e-20 72.4 1.1 2.7 3 0 0 3 3 3 1 Chromosome region maintenance or exportin repeat SAM_decarbox PF01536.16 GAN02957.1 - 1.4e-115 386.1 0.7 1.4e-112 376.2 0.7 3.1 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Herpes_Helicase PF02689.14 GAN02958.1 - 4.5e-09 34.8 0.1 4.8e-09 34.7 0.1 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 GAN02958.1 - 0.0059 16.4 0.2 0.046 13.6 0.2 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain RicinB_lectin_2 PF14200.6 GAN02960.1 - 2.8e-25 88.8 5.3 7.2e-12 45.9 0.1 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN02960.1 - 6.1e-12 45.9 0.2 5.3e-11 42.9 0.3 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PAS_7 PF12860.7 GAN02960.1 - 0.016 15.3 0.0 23 5.2 0.0 3.1 2 1 1 3 3 3 0 PAS fold Sugar_tr PF00083.24 GAN02961.1 - 1.5e-124 416.4 22.2 2.4e-124 415.6 22.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter SNF2_N PF00176.23 GAN02961.1 - 6e-54 183.1 0.5 1.1e-53 182.3 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain MFS_1 PF07690.16 GAN02961.1 - 4.1e-23 81.9 23.9 4.1e-23 81.9 23.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Helicase_C PF00271.31 GAN02961.1 - 1.4e-06 28.6 0.2 4.8e-06 26.9 0.2 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 GAN02961.1 - 1.5e-05 24.7 7.4 3.8e-05 23.4 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN02961.1 - 7.3e-05 23.0 8.8 0.00015 22.0 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAN02961.1 - 0.00013 21.8 10.3 0.00025 20.8 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN02961.1 - 0.00023 20.9 7.4 0.00051 19.9 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN02961.1 - 0.065 13.2 11.7 0.13 12.2 11.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain CPDase PF07823.11 GAN02961.1 - 0.092 12.4 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein zf-C3HC4_4 PF15227.6 GAN02961.1 - 0.73 10.0 6.6 1.7 8.9 6.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAN02961.1 - 1.3 9.1 6.1 3.5 7.7 6.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 GAN02961.1 - 1.6 8.6 6.0 3.1 7.8 6.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4337 PF14235.6 GAN02961.1 - 2.1 8.4 6.3 0.57 10.3 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) EAP30 PF04157.16 GAN02962.1 - 3.4e-38 131.3 0.6 5.8e-38 130.5 0.6 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 GAN02962.1 - 6.5e-24 83.9 0.8 1.4e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 GAN02962.1 - 1.6e-05 24.2 17.9 9.4e-05 21.7 3.3 3.6 1 1 1 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 GAN02962.1 - 0.00015 21.7 6.7 0.00023 21.1 5.8 1.8 1 1 1 2 2 2 2 Double zinc ribbon zf-RanBP PF00641.18 GAN02962.1 - 0.0012 18.2 2.2 0.0012 18.2 2.2 3.0 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 GAN02962.1 - 0.15 12.2 12.4 0.33 11.0 0.8 3.1 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger PHD_4 PF16866.5 GAN02962.1 - 2.2 8.4 7.9 6.3 7.0 3.4 2.7 2 1 0 2 2 2 0 PHD-finger Ephrin_rec_like PF07699.13 GAN02962.1 - 3.1 7.6 10.1 3.7 7.4 0.3 2.4 2 0 0 2 2 2 0 Putative ephrin-receptor like OrfB_Zn_ribbon PF07282.11 GAN02962.1 - 9.6 6.2 9.4 3.6 7.6 0.4 3.2 1 1 2 3 3 3 0 Putative transposase DNA-binding domain HMG_box PF00505.19 GAN02963.1 - 6.3e-20 71.4 0.4 1e-19 70.7 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN02963.1 - 6.3e-08 33.1 0.1 1.1e-07 32.3 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain Carb_bind PF10645.9 GAN02963.1 - 0.066 13.5 2.0 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Carbohydrate binding eRF1_1 PF03463.15 GAN02964.1 - 2e-52 176.5 0.1 3.2e-52 175.9 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 GAN02964.1 - 3.9e-30 104.9 0.3 6.1e-30 104.3 0.3 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAN02964.1 - 7.4e-25 87.6 0.0 1.6e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 PDEase_II PF02112.15 GAN02964.1 - 0.02 14.1 0.2 0.033 13.3 0.2 1.4 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II TNV_CP PF03898.13 GAN02964.1 - 0.029 13.6 0.1 0.089 12.1 0.0 1.9 2 0 0 2 2 2 0 Satellite tobacco necrosis virus coat protein HTH_57 PF18679.1 GAN02964.1 - 0.068 13.5 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 ThcOx helix turn helix domain Dict-STAT-coil PF09267.10 GAN02964.1 - 0.16 12.4 0.3 0.51 10.7 0.1 1.9 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Hexokinase_2 PF03727.16 GAN02966.1 - 3.1e-82 275.6 1.7 3.6e-82 275.4 1.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 GAN02966.1 - 2.7e-69 233.1 0.1 4e-69 232.5 0.1 1.3 1 0 0 1 1 1 1 Hexokinase DUF1924 PF09086.11 GAN02966.1 - 0.14 12.5 0.1 3.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) ABC_tran PF00005.27 GAN02967.1 - 9.6e-40 136.3 0.0 2.2e-20 73.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAN02967.1 - 1.4e-15 57.9 8.4 0.00057 19.8 0.3 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAN02967.1 - 2.7e-08 34.2 0.0 0.0011 19.3 0.0 3.4 3 2 0 3 3 3 2 AAA domain SMC_N PF02463.19 GAN02967.1 - 8.6e-07 28.6 0.0 0.15 11.5 0.0 3.4 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 GAN02967.1 - 3e-06 27.1 0.1 1.2 8.8 0.0 3.7 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_23 PF13476.6 GAN02967.1 - 1.6e-05 25.5 0.2 0.015 15.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 GAN02967.1 - 2.6e-05 24.6 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAN02967.1 - 2.9e-05 23.7 0.0 0.021 14.5 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAN02967.1 - 0.00013 22.0 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 GAN02967.1 - 0.00022 21.7 0.0 2.8 8.4 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAN02967.1 - 0.0003 21.0 0.1 1.3 9.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain Ploopntkinase1 PF18748.1 GAN02967.1 - 0.0004 20.0 0.0 0.069 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 TniB PF05621.11 GAN02967.1 - 0.00042 19.8 0.0 1.5 8.2 0.0 3.2 3 0 0 3 3 3 1 Bacterial TniB protein SbcCD_C PF13558.6 GAN02967.1 - 0.00045 20.4 0.0 3.7 7.9 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 GAN02967.1 - 0.00071 19.6 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAN02967.1 - 0.00079 19.9 0.3 2.9 8.2 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 GAN02967.1 - 0.0008 19.5 0.1 0.014 15.4 0.0 2.7 3 1 0 3 3 2 1 Dynamin family AAA_24 PF13479.6 GAN02967.1 - 0.0017 18.1 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 GAN02967.1 - 0.0022 17.6 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 GAN02967.1 - 0.0022 18.5 0.0 5.4 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 GAN02967.1 - 0.0032 17.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 GAN02967.1 - 0.0055 15.8 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein TsaE PF02367.17 GAN02967.1 - 0.0066 16.4 0.2 1.3 9.1 0.0 2.7 2 1 1 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 GAN02967.1 - 0.0093 14.9 0.0 0.047 12.6 0.0 2.0 2 0 0 2 2 2 1 PrkA AAA domain AAA_17 PF13207.6 GAN02967.1 - 0.0094 16.4 0.1 3.2 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAN02967.1 - 0.01 15.8 0.4 1.1 9.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Roc PF08477.13 GAN02967.1 - 0.011 16.0 0.0 7.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 GAN02967.1 - 0.012 15.6 0.0 2.5 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 GAN02967.1 - 0.013 15.3 0.4 3.7 7.1 0.0 2.9 3 1 0 3 3 2 0 AAA ATPase domain NTPase_1 PF03266.15 GAN02967.1 - 0.022 14.7 0.8 39 4.1 0.0 3.4 3 0 0 3 3 3 0 NTPase dNK PF01712.19 GAN02967.1 - 0.03 14.2 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 GAN02967.1 - 0.037 13.5 0.0 15 5.0 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region SRPRB PF09439.10 GAN02967.1 - 0.038 13.4 0.0 7 6.0 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 GAN02967.1 - 0.044 13.0 0.0 11 5.1 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 GAN02967.1 - 0.052 13.1 0.1 2.4 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain Arf PF00025.21 GAN02967.1 - 0.066 12.7 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_30 PF13604.6 GAN02967.1 - 0.074 12.8 0.1 5.3 6.7 0.0 2.9 3 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GAN02967.1 - 0.078 12.4 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 GAN02967.1 - 0.1 12.5 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 GAN02967.1 - 0.11 12.0 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Cytidylate_kin PF02224.18 GAN02967.1 - 0.13 12.0 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase Mito_carr PF00153.27 GAN02968.1 - 1.4e-54 182.0 0.0 1.6e-18 66.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN02968.1 - 0.0087 15.2 0.0 0.064 12.4 0.0 2.1 2 0 0 2 2 2 1 Gammaproteobacterial serine protease ETF PF01012.21 GAN02969.1 - 1.5e-41 142.2 10.2 2.3e-41 141.7 9.8 1.4 1 1 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 GAN02969.1 - 1.1e-35 121.5 0.5 1.1e-35 121.5 0.5 2.2 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain PG_binding_3 PF09374.10 GAN02969.1 - 0.13 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain SLAIN PF15301.6 GAN02970.1 - 0.014 14.7 0.6 0.024 13.9 0.6 1.3 1 1 0 1 1 1 0 SLAIN motif-containing family Exo_endo_phos PF03372.23 GAN02971.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAN02971.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RNase_T PF00929.24 GAN02972.1 - 9.7e-29 101.0 0.1 1.5e-28 100.4 0.1 1.3 1 0 0 1 1 1 1 Exonuclease SAP PF02037.27 GAN02972.1 - 5.6e-06 26.0 0.3 1.4e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 SAP domain Imm44 PF15571.6 GAN02972.1 - 0.031 14.5 0.4 0.076 13.3 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 44 DUF5302 PF17227.2 GAN02972.1 - 0.047 14.7 2.4 0.11 13.5 2.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5302) DUF5051 PF16473.5 GAN02972.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like AA_permease_2 PF13520.6 GAN02973.1 - 2e-67 227.9 37.1 2.5e-67 227.6 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN02973.1 - 7.6e-34 117.1 34.3 1.1e-33 116.6 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease TraQ PF09679.10 GAN02973.1 - 0.19 11.7 1.5 3.5 7.6 0.0 3.2 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) Ank_2 PF12796.7 GAN02974.1 - 1.9e-19 70.0 0.0 1.1e-08 35.5 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN02974.1 - 2.2e-13 49.0 0.2 0.017 15.6 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 GAN02974.1 - 5.5e-13 48.7 0.2 0.017 15.5 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 GAN02974.1 - 3.5e-12 46.6 0.0 7.3e-06 26.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN02974.1 - 1.6e-09 37.9 3.9 0.069 13.5 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) SpoVIF PF14069.6 GAN02974.1 - 0.12 12.2 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F Prefoldin_2 PF01920.20 GAN02975.1 - 7.3e-19 67.7 1.8 9.3e-19 67.4 1.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Seryl_tRNA_N PF02403.22 GAN02975.1 - 0.72 10.1 5.8 0.69 10.2 1.0 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-AN1 PF01428.16 GAN02976.1 - 1.9e-20 72.7 28.5 7.6e-11 42.0 8.2 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 GAN02976.1 - 0.00039 20.7 19.2 0.0085 16.4 5.7 2.5 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Caudo_TAP PF02413.17 GAN02976.1 - 0.0076 16.4 1.1 0.012 15.8 1.1 1.3 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK HLH PF00010.26 GAN02976.1 - 0.097 12.7 1.1 0.22 11.5 1.1 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain zf-ribbon_3 PF13248.6 GAN02976.1 - 0.38 10.2 8.8 9.6 5.8 0.2 4.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 GAN02976.1 - 0.63 11.0 14.3 18 6.5 2.1 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3139 PF11337.8 GAN02977.1 - 0.6 10.8 3.6 3 8.5 1.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) Mannosyl_trans3 PF11051.8 GAN02981.1 - 9e-46 156.4 0.1 1e-44 153.0 0.1 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_15 PF01793.16 GAN02982.1 - 1.4e-76 257.8 12.3 1.4e-76 257.8 12.3 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 GAN02982.1 - 0.13 12.5 1.2 0.25 11.6 1.2 1.5 1 0 0 1 1 1 0 EGF domain DUF1192 PF06698.11 GAN02983.1 - 0.00049 20.1 17.5 0.11 12.6 2.0 4.5 3 1 1 4 4 4 3 Protein of unknown function (DUF1192) Lectin_N PF03954.14 GAN02983.1 - 0.019 14.7 4.2 3.4 7.4 0.1 3.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 GAN02983.1 - 0.85 9.8 20.8 4.3 7.5 6.2 3.5 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 GAN02983.1 - 2.1 8.6 10.1 0.68 10.2 2.2 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ras PF00071.22 GAN02984.1 - 1.4e-42 145.0 0.1 1.6e-42 144.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN02984.1 - 7.6e-22 77.8 0.1 1.4e-21 76.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN02984.1 - 1.3e-09 37.7 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN02984.1 - 9.1e-05 22.1 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN02984.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RhoGAP PF00620.27 GAN02985.1 - 8.3e-42 142.6 0.4 8.3e-42 142.6 0.4 2.4 3 0 0 3 3 3 1 RhoGAP domain TMF_TATA_bd PF12325.8 GAN02985.1 - 0.012 15.8 3.2 0.012 15.8 3.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 GAN02985.1 - 0.032 14.1 2.8 0.099 12.5 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ERM PF00769.19 GAN02985.1 - 0.6 9.9 13.3 0.5 10.2 7.2 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family ZapB PF06005.12 GAN02985.1 - 1.8 9.0 14.2 0.11 13.0 4.6 2.9 2 0 0 2 2 2 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 GAN02985.1 - 1.9 8.6 12.1 0.23 11.6 2.8 3.0 3 0 0 3 3 3 0 Tropomyosin like Laminin_II PF06009.12 GAN02985.1 - 3.1 7.8 9.8 0.31 11.1 5.0 1.8 2 0 0 2 2 2 0 Laminin Domain II APG6_N PF17675.1 GAN02985.1 - 3.5 8.2 15.5 0.16 12.5 8.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TFIIA PF03153.13 GAN02985.1 - 4.8 7.1 14.0 8.3 6.3 14.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4181 PF13789.6 GAN02986.1 - 3.7 7.9 13.5 9.9 6.5 12.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) Adaptin_N PF01602.20 GAN02987.1 - 5.3e-44 150.7 13.1 7.5e-44 150.2 13.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 GAN02987.1 - 1.7e-11 44.4 0.4 4.8e-11 42.9 0.4 1.7 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 GAN02987.1 - 1.2e-07 31.9 0.3 1.2e-07 31.9 0.3 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAN02987.1 - 7.5e-05 23.0 0.1 0.0028 18.0 0.1 3.0 3 0 0 3 3 3 1 HEAT repeats SRF-TF PF00319.18 GAN02988.1 - 1.3e-21 75.8 0.1 1.9e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Vac7 PF12751.7 GAN02988.1 - 0.0034 16.9 0.5 0.0042 16.6 0.5 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 TFIIA PF03153.13 GAN02988.1 - 0.017 15.1 7.8 0.016 15.3 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.11 GAN02988.1 - 0.37 9.6 3.3 0.46 9.3 3.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF908 PF06012.12 GAN02988.1 - 0.68 9.3 4.7 0.9 8.9 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Herpes_UL32 PF06070.11 GAN02988.1 - 6.9 4.3 9.7 9.2 3.9 9.7 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 HSF_DNA-bind PF00447.17 GAN02989.1 - 2.7e-29 101.6 1.8 2.7e-29 101.6 1.8 3.1 3 0 0 3 3 2 1 HSF-type DNA-binding Response_reg PF00072.24 GAN02989.1 - 1.2e-14 54.4 0.2 4.1e-14 52.7 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain DUF2722 PF10846.8 GAN02989.1 - 0.00027 20.0 17.1 0.00027 20.0 17.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 GAN02989.1 - 0.0051 16.5 31.4 0.0051 16.5 31.4 4.1 2 2 1 4 4 3 1 Spt20 family ALMT PF11744.8 GAN02989.1 - 0.78 8.5 22.0 0.0078 15.1 12.1 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter EOS1 PF12326.8 GAN02989.1 - 0.86 9.5 7.7 1.1 9.2 2.9 2.4 2 0 0 2 2 2 0 N-glycosylation protein CobT PF06213.12 GAN02989.1 - 1.5 8.2 20.6 0.3 10.4 12.1 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT ABC2_membrane_2 PF12679.7 GAN02989.1 - 1.9 7.7 6.3 1 8.6 2.4 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein LMBR1 PF04791.16 GAN02989.1 - 4.7 6.0 16.8 0.12 11.2 9.8 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein CIAPIN1 PF05093.13 GAN02989.1 - 5.9 7.5 9.8 64 4.1 6.4 2.8 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Tristanin_u2 PF16638.5 GAN02989.1 - 7.3 7.4 20.2 7.9 7.3 9.7 2.9 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers EPL1 PF10513.9 GAN02989.1 - 7.8 6.9 23.4 0.044 14.2 4.5 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like PepSY_TM PF03929.16 GAN02989.1 - 9.7 5.8 8.3 3.7 7.1 1.9 2.3 2 0 0 2 2 2 0 PepSY-associated TM region PIG-Y PF15159.6 GAN02990.1 - 0.0098 16.8 0.1 0.015 16.2 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HCMV_UL124 PF17609.2 GAN02990.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function TFA2_Winged_2 PF18121.1 GAN02991.1 - 2.1e-19 69.0 0.2 3.8e-19 68.1 0.2 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 GAN02991.1 - 1.2e-18 67.1 0.7 5.4e-18 65.0 0.1 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain TBPIP PF07106.13 GAN02991.1 - 0.017 15.1 0.3 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain HALZ PF02183.18 GAN02991.1 - 0.043 14.0 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mt_ATP-synt_B PF05405.14 GAN02992.1 - 2.3e-46 157.4 7.6 3.4e-46 156.8 7.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) WD40 PF00400.32 GAN02994.1 - 5.4e-08 33.4 3.6 0.75 10.8 0.4 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02994.1 - 0.0015 18.7 0.0 0.19 12.0 0.0 2.8 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN02995.1 - 8.4e-05 23.3 0.0 0.0015 19.4 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN02995.1 - 0.0043 17.3 0.0 0.045 14.1 0.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain EspF PF04806.12 GAN02996.1 - 0.11 12.9 1.1 0.11 12.9 1.1 1.5 2 0 0 2 2 2 0 EspF protein repeat AMP-binding PF00501.28 GAN02997.1 - 3.5e-71 240.0 0.3 5.7e-30 104.2 0.2 3.3 3 0 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 GAN02997.1 - 4.8e-12 46.7 0.0 2e-11 44.7 0.0 2.1 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 GAN02997.1 - 0.015 15.3 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Cation_efflux PF01545.21 GAN02998.1 - 4.2e-09 36.4 8.9 6.2e-09 35.9 8.9 1.2 1 0 0 1 1 1 1 Cation efflux family Hydrolase_4 PF12146.8 GAN02999.1 - 1e-15 57.7 0.0 2.6e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN02999.1 - 2.7e-12 46.9 0.1 7.3e-07 29.1 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAN02999.1 - 0.00012 21.6 0.0 0.0012 18.4 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAN02999.1 - 0.0002 22.0 0.0 0.00024 21.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 GAN02999.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 GAN02999.1 - 0.004 15.9 0.0 2.5 6.7 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 GAN02999.1 - 0.0075 15.8 0.0 0.031 13.8 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 GAN02999.1 - 0.0083 16.0 0.0 0.097 12.5 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 GAN02999.1 - 0.048 12.6 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 GAN02999.1 - 0.05 13.5 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sugar_tr PF00083.24 GAN03000.1 - 1.2e-92 311.2 32.6 1.5e-92 310.8 32.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3808 PF10300.9 GAN03000.1 - 1.3e-55 189.1 5.5 2.6e-54 184.7 0.5 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) MFS_1 PF07690.16 GAN03000.1 - 9.6e-20 70.8 47.4 4e-19 68.8 17.3 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TPR_2 PF07719.17 GAN03000.1 - 0.15 12.2 0.0 2.7 8.3 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HSP20 PF00011.21 GAN03001.1 - 8.9e-07 29.0 0.2 0.0028 17.8 0.2 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family MYCBPAP PF14646.6 GAN03001.1 - 0.0027 16.7 0.1 0.0032 16.5 0.1 1.1 1 0 0 1 1 1 1 MYCBP-associated protein family RRM_1 PF00076.22 GAN03002.1 - 5.5e-23 80.6 0.6 5.4e-10 39.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN03002.1 - 9.4e-12 44.6 0.1 0.00043 20.1 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF4523 PF15023.6 GAN03002.1 - 5e-06 26.4 0.6 0.0083 16.0 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 GAN03002.1 - 0.0003 20.8 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif DUF1866 PF08952.11 GAN03002.1 - 0.0012 18.8 0.0 1.4 8.8 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 GAN03002.1 - 0.0028 17.6 0.0 20 5.3 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 GAN03002.1 - 0.045 13.4 0.0 0.86 9.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 GAN03004.1 - 8.2e-62 209.3 22.1 2e-37 129.3 7.1 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN03004.1 - 5e-54 182.5 0.0 1.2e-31 110.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN03004.1 - 4.7e-09 36.0 5.8 0.00047 19.7 2.8 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAN03004.1 - 2.3e-06 28.3 2.4 0.0023 18.5 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 GAN03004.1 - 4.2e-06 26.4 0.3 0.071 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 GAN03004.1 - 9.6e-06 24.9 0.1 0.015 14.4 0.2 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 GAN03004.1 - 3e-05 23.7 0.0 0.041 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAN03004.1 - 3e-05 24.5 0.3 0.22 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 GAN03004.1 - 0.00017 21.8 1.2 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 GAN03004.1 - 0.00039 20.2 0.0 1.5 8.5 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_22 PF13401.6 GAN03004.1 - 0.00077 19.8 5.9 0.13 12.6 0.8 3.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAN03004.1 - 0.0013 19.3 0.2 3.6 8.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GAN03004.1 - 0.0013 17.9 1.6 0.14 11.3 0.6 3.1 2 1 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 GAN03004.1 - 0.0013 18.9 4.0 0.047 13.8 0.1 3.8 4 1 0 4 4 3 1 AAA domain AAA_24 PF13479.6 GAN03004.1 - 0.0015 18.3 0.4 0.43 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAN03004.1 - 0.0018 18.1 1.6 4.2 7.1 0.1 3.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system EMC3_TMCO1 PF01956.16 GAN03004.1 - 0.0019 17.9 1.5 0.0045 16.7 1.5 1.6 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RsgA_GTPase PF03193.16 GAN03004.1 - 0.0021 18.0 0.1 0.24 11.3 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAN03004.1 - 0.0026 17.8 0.4 0.81 9.8 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 GAN03004.1 - 0.0061 16.8 0.0 42 4.5 0.0 3.8 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 GAN03004.1 - 0.0082 16.1 3.4 0.57 10.1 0.1 3.1 3 0 0 3 3 3 1 NACHT domain Dynamin_N PF00350.23 GAN03004.1 - 0.009 16.1 0.8 0.45 10.6 0.0 2.7 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 GAN03004.1 - 0.015 14.6 0.3 2.9 7.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAN03004.1 - 0.028 13.7 0.2 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 GAN03004.1 - 0.03 13.9 3.8 0.14 11.8 0.6 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 GAN03004.1 - 0.053 14.0 0.6 8.7 6.8 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAN03004.1 - 0.055 13.0 0.2 8.1 5.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 GAN03004.1 - 0.07 12.6 0.5 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein ResIII PF04851.15 GAN03004.1 - 0.083 12.9 0.0 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_15 PF13175.6 GAN03004.1 - 0.097 12.4 2.3 9.4 5.8 0.5 2.4 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 GAN03004.1 - 0.14 12.3 0.5 23 5.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 GAN03004.1 - 0.2 12.1 0.6 26 5.3 0.1 3.0 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 GAN03004.1 - 0.29 10.8 2.3 2.6 7.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 GAN03004.1 - 0.34 10.8 1.5 22 4.9 0.1 2.6 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 GAN03004.1 - 0.34 10.6 3.6 6.5 6.5 0.4 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 GAN03004.1 - 0.39 10.7 1.9 63 3.6 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 GAN03004.1 - 0.46 9.9 1.6 26 4.2 0.1 3.4 3 0 0 3 3 3 0 PhoH-like protein DEAD PF00270.29 GAN03004.1 - 0.47 10.2 2.7 10 5.8 0.1 3.4 4 0 0 4 4 3 0 DEAD/DEAH box helicase AAA_14 PF13173.6 GAN03004.1 - 1.6 8.8 4.3 13 5.8 0.1 3.6 4 0 0 4 4 3 0 AAA domain Kinesin PF00225.23 GAN03005.1 - 3.7e-30 105.0 2.5 1.4e-29 103.1 2.5 1.9 1 1 0 1 1 1 1 Kinesin motor domain DUF1843 PF08898.10 GAN03005.1 - 0.011 16.2 0.4 0.27 11.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) MEDS PF14417.6 GAN03005.1 - 0.018 14.9 0.2 0.56 10.0 0.1 2.4 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain APG6_N PF17675.1 GAN03005.1 - 0.065 13.8 7.0 0.032 14.7 3.6 2.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 GAN03005.1 - 0.072 12.9 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF1664 PF07889.12 GAN03005.1 - 0.078 13.0 1.1 0.18 11.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Microtub_bd PF16796.5 GAN03005.1 - 0.11 12.4 1.7 0.42 10.6 0.0 2.4 2 1 0 2 2 2 0 Microtubule binding IFP_35_N PF07334.13 GAN03005.1 - 0.14 12.2 1.0 0.42 10.7 1.0 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Cep57_CLD_2 PF14197.6 GAN03005.1 - 0.18 11.9 3.6 0.26 11.4 1.3 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 SR-25 PF10500.9 GAN03005.1 - 0.19 11.3 7.6 0.36 10.4 7.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fungal_TACC PF12709.7 GAN03005.1 - 1.1 9.7 4.5 5.6 7.5 0.7 3.5 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins RnaseA PF00074.20 GAN03008.1 - 0.16 12.4 3.6 0.33 11.4 3.6 1.5 1 0 0 1 1 1 0 Pancreatic ribonuclease Suf PF05843.14 GAN03008.1 - 0.59 10.1 6.3 0.1 12.6 1.5 1.8 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) DUF2526 PF10735.9 GAN03008.1 - 2 8.6 9.4 0.34 11.1 4.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2526) DUF3682 PF12446.8 GAN03008.1 - 3.5 8.1 7.8 11 6.6 7.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Usp PF00582.26 GAN03010.1 - 2.6e-12 47.4 0.0 2e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Universal stress protein family Oxidored_nitro PF00148.19 GAN03010.1 - 0.062 12.0 0.1 0.2 10.4 0.0 1.6 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DUF5388 PF17363.2 GAN03010.1 - 0.073 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5388) Pkinase PF00069.25 GAN03011.1 - 4.3e-70 236.1 0.0 6.6e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03011.1 - 3.4e-49 167.5 0.0 5.9e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAN03011.1 - 2.4e-22 79.0 0.3 1.1e-21 76.9 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAN03011.1 - 1.3e-06 27.5 0.8 3.6e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN03011.1 - 1.3e-05 24.7 0.0 3.4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAN03011.1 - 0.0091 15.4 0.1 0.024 14.0 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN03011.1 - 0.034 14.1 0.1 1.3 8.9 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAN03011.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HEPN_AbiA_CTD PF18732.1 GAN03011.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain Haspin_kinase PF12330.8 GAN03011.1 - 0.65 8.9 5.2 2.1 7.2 5.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Orf78 PF06024.12 GAN03012.1 - 0.86 9.9 3.1 19 5.6 1.4 2.0 1 1 1 2 2 2 0 Orf78 (ac78) zf-C2H2 PF00096.26 GAN03013.1 - 9.8e-15 54.1 17.4 5.7e-05 23.4 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type Myb_DNA-binding PF00249.31 GAN03013.1 - 9.1e-14 51.4 0.6 3.6e-13 49.5 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN03013.1 - 2.7e-12 46.7 0.6 2.7e-12 46.7 0.6 2.4 3 0 0 3 3 2 1 Myb-like DNA-binding domain zf-H2C2_2 PF13465.6 GAN03013.1 - 6.6e-09 35.8 15.1 7.6e-05 23.0 0.4 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAN03013.1 - 3.3e-08 33.3 9.5 0.00051 20.0 0.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAN03013.1 - 1.3e-07 31.8 14.4 0.013 16.3 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger CHDCT2 PF08074.11 GAN03013.1 - 0.0058 16.8 0.0 0.0058 16.8 0.0 4.6 3 2 2 5 5 4 1 CHDCT2 (NUC038) domain SLIDE PF09111.10 GAN03013.1 - 0.0058 16.6 0.0 0.0058 16.6 0.0 3.0 4 0 0 4 4 2 1 SLIDE Rap1_C PF11626.8 GAN03013.1 - 0.013 15.5 0.3 0.15 12.1 0.1 2.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_8 PF15909.5 GAN03013.1 - 0.021 15.1 3.0 0.036 14.4 1.3 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 GAN03013.1 - 0.11 12.9 10.3 3.6 8.1 2.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 GAN03013.1 - 0.91 10.0 11.1 6.4 7.3 0.1 4.0 3 1 1 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 GAN03013.1 - 1.2 9.1 6.8 11 6.0 0.1 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 GAN03013.1 - 1.4 9.3 5.7 35 4.8 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TFIIA PF03153.13 GAN03013.1 - 4.6 7.1 73.8 0.011 15.8 39.8 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_7 PF15963.5 GAN03013.1 - 5.3 7.0 8.0 0.59 10.1 0.1 3.3 3 0 0 3 3 3 0 Myb DNA-binding like Carn_acyltransf PF00755.20 GAN03014.1 - 2.5e-212 706.7 0.0 2.8e-212 706.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TSNR_N PF04705.12 GAN03014.1 - 0.12 12.4 0.0 5.6 7.1 0.0 2.9 2 1 0 2 2 2 0 Thiostrepton-resistance methylase, N terminus FAD_binding_2 PF00890.24 GAN03015.1 - 1.2e-125 419.9 4.4 1.6e-125 419.5 4.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAN03015.1 - 3.5e-45 153.1 0.4 5.3e-45 152.5 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 GAN03015.1 - 3.2e-06 26.6 0.4 0.00072 18.9 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAN03015.1 - 1.6e-05 24.3 0.4 0.017 14.4 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 GAN03015.1 - 1.7e-05 24.1 2.0 0.014 14.5 2.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAN03015.1 - 0.0026 16.9 0.8 0.019 14.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAN03015.1 - 0.0029 16.9 0.3 0.0045 16.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAN03015.1 - 0.035 12.8 2.0 0.47 9.1 0.9 2.8 4 0 0 4 4 4 0 HI0933-like protein DAO PF01266.24 GAN03015.1 - 0.038 13.6 1.1 0.072 12.7 1.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Bestrophin PF01062.21 GAN03016.1 - 0.03 13.7 1.0 0.48 9.8 0.2 2.2 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF1465 PF07323.12 GAN03016.1 - 0.17 11.7 5.4 1.8 8.4 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) THOC7 PF05615.13 GAN03016.1 - 0.25 11.6 7.6 0.37 11.1 6.2 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 AMP-binding PF00501.28 GAN03018.1 - 6.3e-94 314.9 0.2 7.5e-94 314.7 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN03018.1 - 6.8e-21 75.0 0.1 1.5e-20 74.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tetraspanin PF00335.20 GAN03019.1 - 0.045 13.4 0.3 0.079 12.7 0.3 1.6 1 1 0 1 1 1 0 Tetraspanin family ETRAMP PF09716.10 GAN03019.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3181 PF11378.8 GAN03021.1 - 0.027 14.8 0.0 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3181) Transformer PF06495.11 GAN03021.1 - 0.032 14.3 5.3 0.04 14.0 5.3 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein DUF4869 PF16163.5 GAN03021.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) SR-25 PF10500.9 GAN03021.1 - 6.4 6.3 16.0 7.8 6.0 16.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_hydro_18 PF00704.28 GAN03022.1 - 1.5e-62 212.1 4.8 1.5e-62 212.1 4.8 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 GAN03022.1 - 0.0049 17.4 10.0 0.0049 17.4 10.0 3.7 3 0 0 3 3 3 1 Carbohydrate binding domain tRNA_synthFbeta PF17759.1 GAN03023.1 - 9.5e-47 159.2 0.0 1.3e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 GAN03023.1 - 9e-30 102.7 0.4 4.1e-29 100.6 0.1 2.1 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GAN03023.1 - 3.8e-27 95.0 0.1 6.2e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GAN03023.1 - 4.3e-21 75.0 0.0 3.5e-18 65.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 GAN03023.1 - 0.028 13.9 0.0 0.099 12.1 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF2740 PF10872.8 GAN03023.1 - 0.041 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) T6PP_N PF18572.1 GAN03023.1 - 0.098 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SH3BGR PF04908.15 GAN03024.1 - 7.2e-14 51.8 0.1 7.2e-14 51.8 0.1 2.7 3 1 1 4 4 4 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 GAN03024.1 - 2.9e-05 24.2 0.0 0.00014 22.0 0.0 2.3 1 0 0 1 1 1 1 Glutaredoxin DAGK_cat PF00781.24 GAN03024.1 - 0.14 11.8 0.0 0.14 11.8 0.0 3.4 3 1 1 4 4 4 0 Diacylglycerol kinase catalytic domain DUF1574 PF07611.11 GAN03024.1 - 0.15 11.4 0.1 0.15 11.4 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1574) LAM_C PF12544.8 GAN03024.1 - 0.27 11.4 0.1 0.27 11.4 0.1 3.8 4 1 0 4 4 4 0 Lysine-2,3-aminomutase LRR_8 PF13855.6 GAN03025.1 - 4e-27 93.8 25.7 4.9e-06 26.2 0.0 7.4 6 2 1 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAN03025.1 - 5.5e-22 77.5 35.5 9.3e-06 25.9 1.6 7.4 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAN03025.1 - 1e-10 41.4 15.4 0.00022 20.8 0.5 5.6 2 1 3 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 GAN03025.1 - 0.0068 16.8 31.2 2 9.3 0.1 9.7 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 GAN03025.1 - 8.8 6.7 21.0 5.8 7.2 0.3 7.0 9 0 0 9 9 9 0 Leucine Rich repeat zf-C3HC4_3 PF13920.6 GAN03026.1 - 0.024 14.5 9.2 0.047 13.6 8.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 GAN03026.1 - 0.028 14.5 1.7 0.055 13.6 1.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Zn-C2H2_12 PF18112.1 GAN03026.1 - 0.13 12.8 1.0 0.13 12.8 1.0 3.0 2 1 1 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DUF202 PF02656.15 GAN03027.1 - 4.7e-14 52.6 3.7 4.7e-14 52.6 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3149 PF11346.8 GAN03027.1 - 0.21 11.3 4.2 0.5 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Aminotran_1_2 PF00155.21 GAN03028.1 - 2.3e-60 204.7 0.0 3e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAN03028.1 - 0.00022 20.6 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAN03028.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAN03028.1 - 0.042 13.2 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cullin_Nedd8 PF10557.9 GAN03028.1 - 0.044 13.8 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Cullin protein neddylation domain Cys_Met_Meta_PP PF01053.20 GAN03028.1 - 0.067 11.7 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 GAN03029.1 - 2.6e-49 164.9 1.5 6e-22 77.2 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GAN03029.1 - 3.2e-17 63.4 0.4 1.4e-16 61.3 0.4 2.1 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 GAN03029.1 - 9.8e-06 25.3 0.0 0.087 12.7 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 GAN03029.1 - 6.8e-05 22.9 0.1 0.015 15.3 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 GAN03029.1 - 8e-05 22.2 0.0 1.5 8.4 0.0 3.2 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN03029.1 - 0.00092 19.2 0.0 15 5.7 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAN03029.1 - 0.046 13.8 0.0 4.4 7.5 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif RRM_9 PF18444.1 GAN03029.1 - 0.053 13.4 0.4 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 RNA recognition motif Apt1 PF10351.9 GAN03029.1 - 0.93 8.3 13.6 1.3 7.8 13.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C2H2 PF00096.26 GAN03030.1 - 6.7e-10 38.9 16.4 2.1e-05 24.7 2.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN03030.1 - 4e-09 36.5 10.3 1.7e-06 28.2 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN03030.1 - 1.1e-06 29.0 13.2 0.0016 19.1 1.4 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.7 GAN03030.1 - 0.00085 19.6 0.5 0.0024 18.2 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 GAN03030.1 - 0.005 17.1 4.1 0.082 13.2 0.1 2.5 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 GAN03030.1 - 0.015 15.5 0.2 0.059 13.7 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAN03030.1 - 0.024 14.6 0.5 0.024 14.6 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAN03030.1 - 0.11 12.4 3.7 3.8 7.5 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 GAN03030.1 - 0.12 12.2 5.2 0.3 10.9 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 GAN03030.1 - 0.23 11.5 4.5 0.39 10.8 0.4 2.8 2 0 0 2 2 2 0 BED zinc finger zf-UBP PF02148.19 GAN03030.1 - 1.4 9.3 9.5 0.81 10.1 0.2 3.1 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein FLILHELTA PF10306.9 GAN03031.1 - 3.9e-10 40.0 0.0 5.5e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DNA_pol3_beta_3 PF02768.15 GAN03032.1 - 0.014 15.2 1.7 0.022 14.6 1.4 1.6 1 1 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain DHHC PF01529.20 GAN03033.1 - 9.5e-07 29.0 15.4 1.6e-05 25.0 8.6 3.6 2 2 1 3 3 3 2 DHHC palmitoyltransferase DUF2628 PF10947.8 GAN03033.1 - 0.47 10.8 2.9 0.84 10.0 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) UCH PF00443.29 GAN03034.1 - 2.7e-17 63.1 0.1 8.6e-17 61.5 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN03034.1 - 1.5e-09 37.9 0.0 0.00037 20.2 0.1 3.5 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Na_H_Exchanger PF00999.21 GAN03035.1 - 2.5e-59 201.0 25.5 3.3e-59 200.6 25.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 60KD_IMP PF02096.20 GAN03035.1 - 0.36 10.7 7.3 8.9 6.2 3.6 3.2 3 0 0 3 3 3 0 60Kd inner membrane protein CstA PF02554.14 GAN03035.1 - 1.1 8.1 17.6 0.037 12.9 6.6 2.5 2 1 0 2 2 2 0 Carbon starvation protein CstA Phage_holin_3_3 PF16083.5 GAN03035.1 - 4.4 7.5 11.7 2.5 8.3 0.3 3.4 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III sCache_3_3 PF17202.4 GAN03036.1 - 0.062 13.7 0.1 0.068 13.6 0.1 1.1 1 0 0 1 1 1 0 Single cache domain 3 Zn_clus PF00172.18 GAN03037.1 - 1.1e-10 41.4 11.7 1.8e-10 40.7 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Muskelin_N PF06588.11 GAN03038.1 - 4.2e-72 242.2 0.7 8.1e-72 241.3 0.7 1.5 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 GAN03038.1 - 4.6e-26 90.5 8.8 1.9e-07 31.2 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 GAN03038.1 - 2.9e-19 68.8 4.5 0.0023 17.9 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN03038.1 - 8.6e-17 60.5 15.4 1.1e-08 34.5 0.3 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 GAN03038.1 - 9e-14 51.2 6.7 0.0021 18.3 0.1 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 GAN03038.1 - 8.4e-13 48.0 14.7 0.054 13.5 0.0 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 GAN03038.1 - 5.9e-07 29.2 8.2 0.00053 19.9 0.4 5.3 6 0 0 6 6 6 2 Kelch motif Cytochrom_B561 PF03188.16 GAN03038.1 - 2.1e-05 24.7 2.8 4e-05 23.8 2.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Sad1_UNC PF07738.13 GAN03038.1 - 0.0024 17.9 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 GAN03038.1 - 0.0035 17.5 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain FtsK_4TM PF13491.6 GAN03038.1 - 0.88 9.3 3.5 3 7.5 0.0 2.5 2 1 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF4079 PF13301.6 GAN03038.1 - 1.6 8.9 5.3 19 5.4 5.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Bax1-I PF01027.20 GAN03038.1 - 3.5 7.4 12.0 0.34 10.7 3.3 2.3 1 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF998 PF06197.13 GAN03038.1 - 5.4 6.6 10.1 0.99 9.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF2973 PF11189.8 GAN03039.1 - 0.044 13.9 0.5 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) TAFII55_N PF04658.13 GAN03040.1 - 0.042 13.6 1.2 0.096 12.4 0.1 2.2 2 0 0 2 2 2 0 TAFII55 protein conserved region PsbW PF07123.12 GAN03041.1 - 0.02 14.9 0.2 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) DEAD PF00270.29 GAN03042.1 - 6.7e-46 156.2 0.0 1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN03042.1 - 8.8e-31 106.5 0.0 2.5e-27 95.4 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain GUCT PF08152.12 GAN03042.1 - 3.2e-26 91.4 0.0 2.3e-25 88.7 0.0 2.2 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.15 GAN03042.1 - 1.2e-07 31.9 0.3 3.1e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAN03042.1 - 5.5e-05 22.6 9.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 GAN03042.1 - 0.0012 19.1 0.0 0.0057 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAN03042.1 - 0.23 11.9 0.6 0.83 10.1 0.6 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NUDIX PF00293.28 GAN03043.1 - 2.1e-08 34.3 0.0 3.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DnaJ PF00226.31 GAN03044.1 - 2.4e-18 66.0 0.4 3.6e-18 65.4 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L31e PF01198.19 GAN03045.1 - 1.1e-37 128.1 3.0 1.5e-37 127.7 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e ERAP1_C PF11838.8 GAN03045.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Citrate_bind PF16114.5 GAN03046.1 - 1.3e-89 298.4 0.2 2.3e-89 297.6 0.2 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 GAN03046.1 - 1.7e-16 60.3 0.0 1.5e-14 53.8 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 GAN03046.1 - 1.5e-15 57.3 0.1 3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 GAN03046.1 - 3.4e-14 53.3 0.0 7.4e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 GAN03046.1 - 1.1e-06 28.5 0.1 1.2e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 GAN03046.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain BRO1 PF03097.18 GAN03047.1 - 5.7e-98 328.3 1.0 1.9e-97 326.6 0.0 2.4 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAN03047.1 - 5.2e-62 209.8 6.0 1.1e-61 208.7 6.0 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV HMG_box PF00505.19 GAN03047.1 - 1.3e-31 108.8 13.9 1.7e-18 66.8 0.7 3.6 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN03047.1 - 2.7e-22 79.1 2.7 4.4e-10 40.0 0.6 2.7 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 GAN03047.1 - 0.00099 19.0 0.1 0.00099 19.0 0.1 3.2 4 1 0 4 4 4 1 HMG (high mobility group) box 5 CitF PF04223.12 GAN03047.1 - 0.17 10.7 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Frataxin_Cyay PF01491.16 GAN03047.1 - 0.18 11.9 1.5 11 6.2 0.5 3.0 2 0 0 2 2 2 0 Frataxin-like domain Peptidase_M28 PF04389.17 GAN03048.1 - 5.3e-34 117.6 0.1 1.7e-33 116.0 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAN03048.1 - 6.8e-08 32.5 0.1 1.3e-07 31.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 GAN03048.1 - 0.0015 18.1 0.0 0.077 12.5 0.0 2.3 2 0 0 2 2 2 1 Nicastrin Rep_3 PF01051.21 GAN03048.1 - 0.023 14.5 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Initiator Replication protein BOP1NT PF08145.12 GAN03049.1 - 7.9e-115 383.2 11.2 1.6e-114 382.3 11.2 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 GAN03049.1 - 3.2e-09 37.2 0.5 6.9e-07 29.9 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN03049.1 - 0.00021 21.5 0.4 0.18 12.1 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cyclin PF08613.11 GAN03050.1 - 2.6e-11 44.2 0.1 2.6e-11 44.2 0.1 3.2 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 GAN03050.1 - 4.5e-05 23.2 0.4 4.5e-05 23.2 0.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain PTS_2-RNA PF01885.16 GAN03051.1 - 1.8e-65 220.4 0.0 2e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family TRP PF06011.12 GAN03053.1 - 5.1e-46 157.3 28.8 7.6e-46 156.7 28.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 GAN03053.1 - 0.00016 22.1 0.0 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAN03053.1 - 0.02 15.3 2.6 0.049 14.0 2.6 1.6 1 0 0 1 1 1 0 ML-like domain Ppx-GppA PF02541.16 GAN03054.1 - 1e-43 149.8 0.0 1.4e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family HlyIII PF03006.20 GAN03054.1 - 0.081 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Haemolysin-III related SUI1 PF01253.22 GAN03056.1 - 6.8e-25 87.4 0.4 8.7e-25 87.1 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 SNF2_N PF00176.23 GAN03057.1 - 1.7e-66 224.4 1.2 8.3e-66 222.1 1.2 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN03057.1 - 5.9e-22 78.1 0.4 2.8e-19 69.5 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAN03057.1 - 1.2e-11 44.4 0.0 7.3e-11 41.8 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAN03057.1 - 1.8e-09 37.8 0.0 7.7e-09 35.8 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAN03057.1 - 1.4e-06 28.2 0.1 5.9e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase OKR_DC_1 PF01276.20 GAN03057.1 - 0.099 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aegerolysin PF06355.13 GAN03057.1 - 0.27 11.3 2.0 0.31 11.1 0.1 2.1 2 0 0 2 2 2 0 Aegerolysin TAA-Trp-ring PF15401.6 GAN03057.1 - 2.7 8.5 5.2 0.56 10.7 0.1 2.6 3 0 0 3 3 3 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin WD40 PF00400.32 GAN03058.1 - 3.9e-05 24.3 6.7 0.001 19.8 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Asp PF00026.23 GAN03059.1 - 6.5e-93 311.6 4.7 7.7e-93 311.4 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN03059.1 - 9e-12 45.6 6.7 4.5e-06 27.0 0.3 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN03059.1 - 0.0019 18.0 0.4 0.13 12.1 0.0 2.9 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAN03059.1 - 0.015 15.9 1.1 1.7 9.3 0.1 2.9 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 GAN03059.1 - 0.062 13.9 0.1 21 5.8 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ribosomal_S17e PF00833.18 GAN03060.1 - 2.8e-62 208.1 0.2 3.2e-62 207.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Glyco_hydro_18 PF00704.28 GAN03061.1 - 5.2e-21 75.7 4.2 2.5e-20 73.5 4.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 GAN03061.1 - 0.0034 17.3 10.9 0.0034 17.3 10.9 2.8 2 1 0 2 2 2 1 Carbohydrate binding domain (family 19) DUF4172 PF13776.6 GAN03061.1 - 0.2 12.0 1.8 0.42 11.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) GATA PF00320.27 GAN03062.1 - 2.4e-15 55.9 5.6 2.4e-15 55.9 5.6 2.0 2 0 0 2 2 2 1 GATA zinc finger CCDC14 PF15254.6 GAN03062.1 - 0.0075 15.0 2.9 0.011 14.5 2.9 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 TauD PF02668.16 GAN03063.1 - 3.4e-42 145.1 0.1 4.6e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2625 PF10946.8 GAN03063.1 - 0.013 14.6 0.0 0.061 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF2625 Phage_coat PF09063.10 GAN03063.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Phage PP7 coat protein tRNA_anti-codon PF01336.25 GAN03064.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 GAN03064.1 - 1e-06 29.3 0.2 1e-06 29.3 0.2 2.0 2 1 0 2 2 2 1 Replication protein A C terminal DUF4777 PF16007.5 GAN03064.1 - 0.036 14.3 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Sigma70_r2 PF04542.14 GAN03064.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 region 2 RMI2 PF16100.5 GAN03064.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 Peptidase_A22B PF04258.13 GAN03065.1 - 3.8e-86 289.2 12.4 5.2e-86 288.7 12.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 GAN03065.1 - 0.0013 18.3 11.8 0.003 17.1 11.8 1.7 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease PGA2 PF07543.12 GAN03065.1 - 2.8 7.9 13.4 0.15 12.0 7.7 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF4536 PF15055.6 GAN03066.1 - 0.11 12.8 5.0 0.18 12.1 4.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) HLH PF00010.26 GAN03067.1 - 1.4e-18 66.6 0.6 5.3e-18 64.7 0.6 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3802 PF12290.8 GAN03067.1 - 0.052 14.0 1.5 0.4 11.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) GRAM PF02893.20 GAN03068.1 - 3.9e-25 88.0 0.1 9.4e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 GRAM domain VASt PF16016.5 GAN03068.1 - 4.3e-19 69.4 1.0 4.3e-19 69.4 1.0 2.7 3 1 0 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain CMS1 PF14617.6 GAN03069.1 - 2.8e-45 154.6 0.6 3.8e-45 154.2 0.6 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 GAN03069.1 - 3.3e-07 30.3 0.1 4e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase GEN1_C PF18380.1 GAN03069.1 - 0.15 13.0 3.2 0.33 11.9 3.2 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain DEAD PF00270.29 GAN03070.1 - 4.4e-49 166.6 0.0 7.5e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN03070.1 - 5.4e-33 113.7 0.2 3.1e-32 111.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN03070.1 - 9.7e-09 35.5 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAN03070.1 - 1.1e-06 28.1 0.0 2.4e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Cyt-b5 PF00173.28 GAN03071.1 - 5e-22 77.8 0.4 5e-22 77.8 0.4 2.3 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 GAN03071.1 - 3.6e-12 46.8 20.9 3.6e-12 46.8 20.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 GAN03071.1 - 0.1 12.8 0.3 0.23 11.7 0.3 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region TMEM189_B_dmain PF10520.9 GAN03071.1 - 0.11 12.7 7.9 0.051 13.7 2.1 2.3 1 1 1 2 2 2 0 B domain of TMEM189, localisation domain DUF4260 PF14079.6 GAN03071.1 - 0.22 11.5 6.7 0.053 13.5 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) Gti1_Pac2 PF09729.9 GAN03073.1 - 7.9e-59 198.8 0.3 7.9e-59 198.8 0.3 3.5 2 2 0 2 2 2 1 Gti1/Pac2 family DegT_DnrJ_EryC1 PF01041.17 GAN03073.1 - 0.2 10.9 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family S-methyl_trans PF02574.16 GAN03074.1 - 4.1e-68 230.1 0.0 4.6e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Sulfate_transp PF00916.20 GAN03075.1 - 1.3e-93 313.8 22.5 1.7e-93 313.4 22.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN03075.1 - 4.6e-10 39.2 0.0 9.6e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAN03075.1 - 0.00054 20.2 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN03075.1 - 0.11 12.9 16.4 0.023 15.1 3.2 3.0 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Na_H_antiport_2 PF13726.6 GAN03075.1 - 0.93 9.7 7.5 8.1 6.7 0.7 3.4 2 1 1 3 3 3 0 Na+-H+ antiporter family WAC_Acf1_DNA_bd PF10537.9 GAN03076.1 - 1.7e-33 115.2 0.5 1.7e-33 115.2 0.5 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 GAN03076.1 - 4.2e-20 72.1 0.1 4.2e-20 72.1 0.1 3.8 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 GAN03076.1 - 2.2e-15 56.7 0.1 3.8e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 DDT domain Peptidase_C37 PF05416.12 GAN03076.1 - 0.05 12.1 0.1 0.05 12.1 0.1 2.9 2 1 1 3 3 3 0 Southampton virus-type processing peptidase Fe-ADH PF00465.19 GAN03077.1 - 2e-106 355.9 0.2 2.4e-106 355.6 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAN03077.1 - 2.2e-15 57.1 0.1 7.7e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 GAN03077.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein B12-binding PF02310.19 GAN03077.1 - 0.015 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Cpn60_TCP1 PF00118.24 GAN03078.1 - 7.2e-86 288.8 11.1 1.4e-85 287.8 11.1 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2_aberr PF17017.5 GAN03079.1 - 0.0016 18.6 11.4 0.019 15.1 0.7 3.2 1 1 2 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 GAN03079.1 - 0.037 14.5 17.8 0.06 13.8 0.6 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type S8_pro-domain PF16470.5 GAN03079.1 - 0.098 13.4 0.1 1.4 9.7 0.2 2.5 2 0 0 2 2 2 0 Peptidase S8 pro-domain UDPGT PF00201.18 GAN03080.1 - 2.2e-17 63.1 0.0 2.5e-14 53.0 0.1 3.0 2 1 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase NCE101 PF11654.8 GAN03080.1 - 1.3e-08 34.4 0.0 2.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Non-classical export protein 1 Glyco_tran_28_C PF04101.16 GAN03080.1 - 2.2e-07 31.0 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 GAN03080.1 - 0.021 14.8 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 zf-C2H2_2 PF12756.7 GAN03081.1 - 1.9e-39 134.1 12.2 4.3e-31 107.2 0.1 3.6 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAN03081.1 - 5.8e-12 45.6 8.1 2.1e-08 34.2 4.6 4.4 5 1 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN03081.1 - 3.2e-07 30.5 8.2 1.3e-05 25.4 2.4 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-DBF PF07535.12 GAN03081.1 - 0.035 14.2 0.7 0.035 14.2 0.7 3.4 4 0 0 4 4 4 0 DBF zinc finger zf-C2H2 PF00096.26 GAN03081.1 - 0.076 13.5 1.5 0.076 13.5 1.5 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 GAN03081.1 - 0.095 12.4 1.7 13 5.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 GAN03081.1 - 0.27 11.1 2.3 4.9 7.1 0.1 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 GAN03081.1 - 0.37 11.8 0.3 0.37 11.8 0.3 5.3 6 0 0 6 6 5 0 C2H2-type zinc finger DUF1644 PF07800.12 GAN03081.1 - 0.48 10.5 8.5 0.66 10.0 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-C2H2_3rep PF18868.1 GAN03081.1 - 0.62 10.8 8.9 30 5.3 0.2 3.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF2340 PF10209.9 GAN03081.1 - 1 9.8 8.3 3.2 8.2 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) Asp PF00026.23 GAN03082.1 - 6.5e-93 311.6 11.3 7.7e-93 311.4 11.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN03082.1 - 6.8e-13 49.2 6.9 6e-06 26.6 0.7 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN03082.1 - 0.00012 22.6 0.5 0.092 13.4 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAN03082.1 - 0.0069 16.9 0.5 2.2 8.9 0.0 3.4 2 2 1 3 3 3 1 gag-polyprotein putative aspartyl protease Invasin_D3 PF09134.10 GAN03082.1 - 0.64 10.4 8.8 2.4 8.5 1.0 2.9 2 1 1 3 3 3 0 Invasin, domain 3 MFS_1 PF07690.16 GAN03083.1 - 1e-37 129.9 66.6 1.7e-29 102.9 37.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN03083.1 - 6.2e-07 28.3 21.6 6.2e-07 28.3 21.6 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 GAN03083.1 - 1.3e-05 24.3 13.5 1.3e-05 24.3 13.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAN03083.1 - 0.0022 16.9 1.2 0.0022 16.9 1.2 2.6 2 1 1 3 3 3 2 MFS_1 like family Neurensin PF14927.6 GAN03083.1 - 7.7 6.2 6.7 5 6.8 0.0 3.4 2 1 1 3 3 3 0 Neurensin DUF755 PF05501.11 GAN03084.1 - 0.0032 17.7 10.5 0.0032 17.7 10.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF755) SURF2 PF05477.11 GAN03084.1 - 1.9 8.1 6.7 3.1 7.4 6.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Zip PF02535.22 GAN03085.1 - 0.17 11.1 0.9 0.17 11.0 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 GAN03085.1 - 9.2 5.6 13.2 9.8 5.5 13.2 1.1 1 0 0 1 1 1 0 SDA1 DnaJ_C PF01556.18 GAN03087.1 - 1.8e-36 125.5 0.2 3.1e-36 124.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN03087.1 - 5.2e-23 80.9 2.9 9.5e-23 80.1 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain MULE PF10551.9 GAN03087.1 - 1.9e-15 57.1 0.8 7.9e-15 55.1 0.0 2.4 2 1 1 3 3 3 1 MULE transposase domain DnaJ_CXXCXGXG PF00684.19 GAN03087.1 - 4.8e-14 52.5 14.2 4.8e-14 52.5 14.2 1.8 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 GAN03087.1 - 0.0017 18.2 3.3 1.1 9.3 0.2 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 GAN03087.1 - 6.8 6.8 9.6 14 5.8 9.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon Amidohydro_1 PF01979.20 GAN03088.1 - 1.4e-17 64.1 0.0 1.1e-15 57.8 0.0 3.3 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAN03088.1 - 6.1e-17 62.2 2.8 1.8e-11 44.2 0.0 3.6 4 0 0 4 4 4 2 Amidohydrolase family PLU-1 PF08429.11 GAN03088.1 - 0.042 13.0 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 PLU-1-like protein HLH PF00010.26 GAN03090.1 - 1.1e-09 38.1 1.5 1.5e-09 37.6 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Fanconi_A PF03511.14 GAN03091.1 - 0.16 11.9 0.0 22 5.1 0.0 2.5 2 1 0 2 2 2 0 Fanconi anaemia group A protein Ecm29 PF13001.7 GAN03092.1 - 3.7e-146 487.7 0.1 3.7e-146 487.7 0.1 2.5 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 GAN03092.1 - 7.1e-09 35.2 20.7 0.019 15.2 0.0 12.1 14 0 0 14 14 14 2 HEAT repeat IFRD PF05004.13 GAN03092.1 - 1.2e-07 31.2 9.5 0.045 12.9 0.4 5.6 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 GAN03092.1 - 1.4e-06 28.7 11.1 0.86 10.2 0.0 8.8 10 1 1 11 11 10 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAN03092.1 - 4.2e-06 27.3 2.8 0.073 13.7 0.0 6.8 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 GAN03092.1 - 0.0062 16.5 0.0 0.57 10.3 0.0 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 GAN03092.1 - 0.04 13.0 11.6 5.9 5.9 0.0 5.0 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal Tti2 PF10521.9 GAN03092.1 - 0.045 13.3 0.1 3.3 7.1 0.0 3.3 3 0 0 3 3 3 0 Tti2 family CLASP_N PF12348.8 GAN03092.1 - 0.07 12.7 6.3 1.4 8.4 0.0 5.3 6 1 0 6 6 6 0 CLASP N terminal SapB_2 PF03489.17 GAN03092.1 - 0.078 13.1 0.7 64 3.8 0.0 4.0 3 0 0 3 3 3 0 Saposin-like type B, region 2 NOC3p PF07540.11 GAN03092.1 - 0.14 12.6 1.8 3.4 8.2 0.1 3.3 3 0 0 3 3 3 0 Nucleolar complex-associated protein B56 PF01603.20 GAN03093.1 - 7.2e-189 628.0 6.6 1.1e-188 627.4 6.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) YesK PF14150.6 GAN03093.1 - 0.12 12.5 1.4 0.32 11.2 1.4 1.7 1 0 0 1 1 1 0 YesK-like protein p450 PF00067.22 GAN03094.1 - 1.2e-88 297.9 0.0 2e-88 297.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 GAN03094.1 - 7.3e-31 107.5 0.0 1.2e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN03094.1 - 2.1e-24 86.4 1.0 3.3e-22 79.2 1.0 2.8 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAN03094.1 - 1.9e-15 57.4 0.1 6.3e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FMN_red PF03358.15 GAN03094.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF99 PF01949.16 GAN03094.1 - 0.032 13.6 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF99 Flavodoxin_NdrI PF07972.11 GAN03094.1 - 0.07 13.3 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 NrdI Flavodoxin like LSM PF01423.22 GAN03095.1 - 1.1e-15 57.1 0.1 1.4e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF5440 PF17509.2 GAN03095.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5440) RTC PF01137.21 GAN03096.1 - 4.1e-63 212.5 0.0 4.7e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GAN03096.1 - 3.5e-38 130.2 0.0 5.8e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RNA_pol_L_2 PF13656.6 GAN03097.1 - 3.5e-28 97.2 0.0 1.2e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAN03097.1 - 1.4e-08 34.1 0.0 2.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3730 PF12530.8 GAN03098.1 - 0.00034 20.3 3.4 0.0014 18.2 2.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) Cnd1 PF12717.7 GAN03098.1 - 2.6 8.1 9.5 18 5.3 0.0 5.0 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DEAD PF00270.29 GAN03099.1 - 4.8e-24 85.1 0.0 8.4e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN03099.1 - 3.7e-12 46.6 0.0 9.6e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN03099.1 - 0.00012 22.1 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAN03099.1 - 0.0041 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Baculo_helicase PF04735.12 GAN03099.1 - 0.028 12.0 0.0 0.037 11.6 0.0 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase bZIP_2 PF07716.15 GAN03100.1 - 2.1e-09 37.3 3.8 2.1e-09 37.3 3.8 2.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN03100.1 - 3.2e-08 33.5 8.3 3.2e-08 33.5 8.3 2.6 2 1 1 3 3 3 1 bZIP transcription factor ATG16 PF08614.11 GAN03100.1 - 0.00055 20.2 3.3 0.00074 19.8 3.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_Maf PF03131.17 GAN03100.1 - 0.00067 20.1 3.0 0.0013 19.2 3.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor MPS2 PF17060.5 GAN03100.1 - 0.026 13.8 1.8 0.035 13.4 1.8 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 HAUS-augmin3 PF14932.6 GAN03100.1 - 0.033 13.8 3.8 0.051 13.2 3.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3287 PF11690.8 GAN03100.1 - 0.082 12.6 1.2 0.24 11.1 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Mvb12 PF09452.10 GAN03100.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Cas9_REC PF16592.5 GAN03100.1 - 0.12 11.1 0.6 0.15 10.7 0.6 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 ZapB PF06005.12 GAN03100.1 - 0.24 11.9 3.3 0.24 11.9 2.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB Nup54 PF13874.6 GAN03100.1 - 0.27 11.3 3.4 0.39 10.8 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Ceramidase PF05875.12 GAN03101.1 - 3.3e-52 177.5 11.0 4e-52 177.2 11.0 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 GAN03101.1 - 0.09 12.8 0.9 0.09 12.8 0.9 2.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide HSF_DNA-bind PF00447.17 GAN03102.1 - 9.5e-32 109.5 2.9 9.5e-32 109.5 2.9 2.8 3 0 0 3 3 3 1 HSF-type DNA-binding Enkurin PF13864.6 GAN03102.1 - 8.8 6.8 9.0 5.5 7.5 2.5 2.8 2 1 0 2 2 2 0 Calmodulin-binding DUF563 PF04577.14 GAN03103.1 - 7.9e-10 39.2 0.0 1.4e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ketoacyl-synt_2 PF13723.6 GAN03103.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Pox_F15 PF04596.12 GAN03103.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Poxvirus protein F15 Beta_elim_lyase PF01212.21 GAN03105.1 - 3.4e-69 233.4 0.0 4.4e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAN03105.1 - 2e-07 30.6 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAN03105.1 - 0.015 14.6 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAN03105.1 - 0.15 10.5 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PQ-loop PF04193.14 GAN03106.1 - 1.7e-37 127.0 13.8 2.3e-19 68.9 1.4 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 GAN03106.1 - 0.042 13.9 5.7 0.42 10.7 0.3 3.8 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.18 GAN03106.1 - 0.82 10.5 6.7 0.6 10.9 0.5 2.8 2 2 1 3 3 3 0 ER lumen protein retaining receptor Septin PF00735.18 GAN03107.1 - 1.5e-114 382.1 2.1 2.1e-114 381.6 2.1 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 GAN03107.1 - 2.9e-07 30.2 4.4 1.2e-05 25.0 0.2 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN03107.1 - 4.4e-07 30.0 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN03107.1 - 6.1e-06 26.2 3.9 2.3e-05 24.3 0.2 2.8 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 GAN03107.1 - 0.00019 20.8 0.1 0.00019 20.8 0.1 2.2 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 GAN03107.1 - 0.00025 21.3 0.1 0.00077 19.7 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF3584 PF12128.8 GAN03107.1 - 0.00028 18.6 3.4 0.00028 18.6 3.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) IIGP PF05049.13 GAN03107.1 - 0.00053 19.2 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 GAN03107.1 - 0.0034 17.5 6.7 0.4 10.7 0.1 3.5 2 1 1 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.18 GAN03107.1 - 0.0039 16.6 0.0 0.0099 15.3 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Ras PF00071.22 GAN03107.1 - 0.0041 16.7 0.5 0.017 14.7 0.2 2.2 2 1 0 2 2 2 1 Ras family Sigma54_activat PF00158.26 GAN03107.1 - 0.0076 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 GAN03107.1 - 0.008 16.5 0.9 0.036 14.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN03107.1 - 0.0081 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 GAN03107.1 - 0.015 14.7 0.3 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 GAN03107.1 - 0.019 15.5 0.9 0.12 12.9 0.0 2.7 3 1 1 4 4 3 0 ABC transporter FOXP-CC PF16159.5 GAN03107.1 - 0.021 15.4 2.6 0.034 14.8 0.7 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain AAA_29 PF13555.6 GAN03107.1 - 0.033 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 GAN03107.1 - 0.062 12.8 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 GAN03107.1 - 0.062 13.7 0.2 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 GAN03107.1 - 1.9 8.9 18.1 1.4e+02 2.8 18.1 2.2 1 1 0 1 1 1 0 AAA domain Fungal_TACC PF12709.7 GAN03107.1 - 5 7.6 9.2 1.1 9.8 4.6 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Exonuc_VII_L PF02601.15 GAN03107.1 - 5.3 6.5 8.1 9.1 5.7 8.1 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit PAP2 PF01569.21 GAN03108.1 - 0.1 12.4 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily SMI1_KNR4 PF09346.10 GAN03109.1 - 0.021 15.2 0.2 0.04 14.3 0.2 1.5 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) DUF5395 PF17373.2 GAN03109.1 - 0.041 14.5 0.1 0.086 13.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5395) Rad51 PF08423.11 GAN03111.1 - 1.6e-106 355.2 0.0 2.1e-105 351.6 0.0 2.1 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 GAN03111.1 - 2e-12 47.1 0.2 2.9e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 GAN03111.1 - 2.3e-07 30.6 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 GAN03111.1 - 1.2e-06 29.0 0.7 2.9e-06 27.8 0.7 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 GAN03111.1 - 2.7e-06 26.9 0.0 6.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 GAN03111.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_pol_A_CTD PF03118.15 GAN03111.1 - 0.014 15.2 0.3 0.042 13.6 0.3 1.8 1 1 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain AAA PF00004.29 GAN03111.1 - 0.017 15.5 0.0 0.079 13.4 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PTPLA PF04387.14 GAN03112.1 - 3.7e-54 182.9 12.8 6.2e-54 182.1 12.8 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA KilA-N PF04383.13 GAN03114.1 - 0.00028 20.7 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain DUF4452 PF14618.6 GAN03115.1 - 0.00015 21.7 11.2 0.00015 21.7 11.2 3.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4452) MAP65_ASE1 PF03999.12 GAN03115.1 - 0.14 10.8 14.0 0.18 10.5 14.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ORC6 PF05460.13 GAN03115.1 - 2.5 7.3 13.1 3 7.0 13.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NTP_transferase PF00483.23 GAN03116.1 - 3.4e-11 43.2 0.0 1.4e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 GAN03116.1 - 7.4e-11 41.3 10.7 8.2e-05 22.2 10.6 3.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAN03116.1 - 4.2e-07 30.4 0.0 6.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 GAN03116.1 - 4.2e-05 21.9 3.7 8.1e-05 21.0 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 GAN03116.1 - 0.04 12.9 4.2 0.1 11.5 4.2 1.6 1 1 0 1 1 1 0 L-fucokinase TrkA_N PF02254.18 GAN03116.1 - 0.052 13.8 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain zf-CCCH PF00642.24 GAN03117.1 - 4.9e-16 58.2 23.6 4.4e-09 36.0 2.9 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAN03117.1 - 7.9e-11 41.6 18.3 3.2e-05 23.8 5.2 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAN03117.1 - 6.7e-08 32.2 15.5 0.00025 20.8 2.3 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAN03117.1 - 0.0018 18.7 11.5 0.074 13.5 1.0 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GAN03117.1 - 5.7 7.7 20.6 0.97 10.2 2.0 3.2 2 1 1 3 3 3 0 Torus domain DUF3176 PF11374.8 GAN03119.1 - 0.0035 17.5 7.1 0.02 15.1 6.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Inhibitor_I78 PF11720.8 GAN03120.1 - 9.5e-06 25.6 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 GAN03120.1 - 0.0021 18.7 0.3 0.0049 17.5 0.2 1.6 1 1 1 2 2 2 1 Potato inhibitor I family Cu_amine_oxid PF01179.20 GAN03121.1 - 1.4e-159 531.4 1.7 1.8e-159 531.1 1.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAN03121.1 - 1.1e-16 61.1 0.1 3e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 GAN03121.1 - 7.8e-09 35.7 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Ank_4 PF13637.6 GAN03122.1 - 8.1e-16 58.2 0.5 7.1e-10 39.2 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN03122.1 - 1.8e-13 50.9 0.6 1.5e-06 28.7 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAN03122.1 - 6.1e-10 39.1 0.1 0.0032 17.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAN03122.1 - 8.7e-09 34.9 0.2 0.00058 20.1 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAN03122.1 - 2.1e-05 24.7 0.1 0.28 11.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 GAN03122.1 - 3.5e-05 23.6 1.0 0.00086 19.1 0.0 3.1 2 1 0 2 2 2 1 KilA-N domain Lipoprotein_6 PF01441.19 GAN03122.1 - 0.0086 16.1 0.3 0.0086 16.1 0.3 2.4 3 0 0 3 3 3 1 Lipoprotein Med13_C PF06333.12 GAN03122.1 - 2 7.6 6.5 0.25 10.6 2.0 1.8 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Ribosomal_60s PF00428.19 GAN03122.1 - 4.8 7.8 15.3 0.16 12.6 5.7 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein MBOAT_2 PF13813.6 GAN03123.1 - 2e-10 40.8 1.6 1.6e-05 25.1 0.0 2.9 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Cyt_bd_oxida_I PF01654.17 GAN03123.1 - 0.0028 16.4 2.2 0.0028 16.4 2.2 1.8 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit I Med3 PF11593.8 GAN03123.1 - 0.84 8.8 16.6 1.2 8.3 16.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.12 GAN03123.1 - 1.1 7.1 15.6 1.5 6.7 15.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Endomucin PF07010.12 GAN03123.1 - 4.6 7.2 17.8 7.8 6.4 17.8 1.3 1 0 0 1 1 1 0 Endomucin Aldose_epim PF01263.20 GAN03124.1 - 1.2e-86 290.8 0.1 1.3e-86 290.6 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2834 PF11196.8 GAN03125.1 - 0.0026 18.0 2.6 0.0026 18.0 2.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2834) GPR_Gpa2_C PF11970.8 GAN03125.1 - 0.064 13.3 3.1 0.24 11.5 0.1 2.9 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2207 PF09972.9 GAN03126.1 - 2.5 6.8 9.5 0.37 9.5 1.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UBX PF00789.20 GAN03127.1 - 5e-18 65.1 0.0 1.2e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 UBX domain SH3BGR PF04908.15 GAN03127.1 - 0.65 10.2 0.0 0.65 10.2 0.0 2.8 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein TFIIA PF03153.13 GAN03127.1 - 2.4 8.0 25.5 0.2 11.6 20.0 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MBOAT_2 PF13813.6 GAN03128.1 - 0.0032 17.7 0.1 0.0081 16.4 0.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LIX1 PF14954.6 GAN03128.1 - 0.017 14.5 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 Limb expression 1 Creatinase_N_2 PF16189.5 GAN03129.1 - 4.6e-52 176.3 0.2 2.6e-50 170.7 0.1 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GAN03129.1 - 3.1e-43 147.9 0.0 5.7e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 GAN03129.1 - 3.1e-23 81.6 0.0 1.8e-21 76.0 0.0 2.9 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAN03129.1 - 1.2e-20 74.5 0.0 1.5e-17 64.5 0.0 2.7 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain Sds3 PF08598.11 GAN03130.1 - 4e-09 36.8 0.7 4e-09 36.8 0.7 2.7 3 1 0 3 3 3 1 Sds3-like Cofilin_ADF PF00241.20 GAN03131.1 - 6.3e-42 142.2 0.5 7.1e-42 142.0 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-CCHC_3 PF13917.6 GAN03132.1 - 2e-16 59.7 6.7 2e-16 59.7 6.7 1.8 2 0 0 2 2 2 1 Zinc knuckle CLIP1_ZNF PF16641.5 GAN03132.1 - 0.37 10.7 2.4 0.52 10.3 2.4 1.2 1 0 0 1 1 1 0 CLIP1 zinc knuckle SPX PF03105.19 GAN03132.1 - 0.75 9.7 29.8 0.87 9.4 29.8 1.1 1 0 0 1 1 1 0 SPX domain zf-CCHC PF00098.23 GAN03132.1 - 0.77 9.9 3.3 1.4 9.1 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Tmemb_cc2 PF10267.9 GAN03132.1 - 1.8 7.6 13.9 2.4 7.2 13.9 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.9 GAN03132.1 - 8.5 4.8 25.0 9.7 4.6 25.0 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 GAN03132.1 - 8.9 4.5 14.7 10 4.3 14.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Proteasome PF00227.26 GAN03133.1 - 7.5e-56 188.6 0.2 1e-55 188.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAN03133.1 - 2.1e-15 56.1 0.1 3.7e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RRM_1 PF00076.22 GAN03134.1 - 2.2e-17 62.6 0.0 7.2e-08 32.1 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN03134.1 - 0.0091 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif Pkinase PF00069.25 GAN03135.1 - 7.9e-44 150.0 0.0 9.6e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03135.1 - 3.1e-27 95.5 0.0 3.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN03135.1 - 3.3e-06 26.6 0.0 0.0022 17.4 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 GAN03135.1 - 0.0023 17.9 0.0 0.0051 16.8 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Nop16 PF09420.10 GAN03136.1 - 1.3e-60 205.1 11.0 1.5e-60 204.8 11.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF3460 PF11943.8 GAN03136.1 - 0.45 10.8 4.7 0.62 10.4 1.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3460) Cation_efflux PF01545.21 GAN03137.1 - 3.1e-32 111.9 13.1 3.9e-32 111.6 13.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAN03137.1 - 5.1e-09 36.2 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Sulfate_transp PF00916.20 GAN03138.1 - 4.8e-82 275.7 19.2 4.8e-82 275.7 19.2 1.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN03138.1 - 1.8e-21 76.0 0.0 3.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAN03138.1 - 0.044 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 STAS domain Phage_holin_2_3 PF16080.5 GAN03138.1 - 0.44 10.4 2.5 1.6 8.6 2.5 2.0 1 0 0 1 1 1 0 Bacteriophage holin family HP1 WD40 PF00400.32 GAN03139.1 - 1.8e-42 142.5 20.6 7.9e-06 26.5 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN03139.1 - 2.1e-18 66.4 3.2 0.045 14.0 0.0 7.0 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAN03139.1 - 3.8e-08 33.1 0.1 7.1e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 GAN03139.1 - 5.5e-08 32.5 0.1 0.15 11.3 0.0 3.6 1 1 2 4 4 4 4 WD40-like domain Nup160 PF11715.8 GAN03139.1 - 1.7e-07 30.3 14.7 0.12 11.0 0.0 6.4 2 1 4 6 6 6 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAN03139.1 - 4.1e-06 26.8 0.2 0.58 10.2 0.0 4.8 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 GAN03139.1 - 0.00055 19.5 0.1 0.52 9.7 0.0 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 GAN03139.1 - 0.0011 19.4 2.7 4.9 7.8 0.1 5.1 5 0 0 5 5 5 1 PQQ-like domain CDC4_D PF16856.5 GAN03139.1 - 0.0021 17.9 1.7 0.0041 17.0 1.5 1.7 1 1 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box PF00646.33 GAN03139.1 - 0.0035 17.2 0.1 0.0096 15.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain PilO PF04350.13 GAN03139.1 - 0.013 15.7 0.3 0.024 14.8 0.3 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO Ge1_WD40 PF16529.5 GAN03139.1 - 0.056 12.4 0.1 0.55 9.1 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 GAN03139.1 - 0.14 11.1 2.6 25 3.6 0.0 4.3 1 1 5 6 6 6 0 Partner and localizer of BRCA2 WD40 domain Syntaxin PF00804.25 GAN03140.1 - 2.6e-35 121.9 18.3 4.7e-35 121.1 18.3 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAN03140.1 - 1.2e-12 47.6 1.2 1.2e-12 47.6 1.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 GAN03140.1 - 1.5e-05 25.3 10.0 1.5e-05 25.3 10.0 2.6 2 1 1 3 3 3 1 Syntaxin-like protein MCPsignal PF00015.21 GAN03140.1 - 0.0066 16.3 6.7 0.0066 16.3 6.7 3.1 1 1 3 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA1 PF07160.12 GAN03140.1 - 0.014 15.2 2.1 0.014 15.2 2.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF2203 PF09969.9 GAN03140.1 - 0.039 14.7 7.3 0.38 11.5 0.3 3.2 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) PDCD7 PF16021.5 GAN03140.1 - 0.04 13.0 15.3 0.91 8.6 15.3 2.1 1 1 0 1 1 1 0 Programmed cell death protein 7 RPW8 PF05659.11 GAN03140.1 - 0.054 13.2 2.2 0.16 11.7 0.1 2.5 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1706 PF08020.11 GAN03140.1 - 0.51 10.2 5.0 0.66 9.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1706) LMBR1 PF04791.16 GAN03140.1 - 0.54 9.1 19.5 11 4.8 19.5 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4094 PF13334.6 GAN03140.1 - 1.6 9.2 13.3 0.065 13.7 1.4 3.4 2 2 0 3 3 3 0 Domain of unknown function (DUF4094) MCU PF04678.13 GAN03140.1 - 2.3 8.3 12.0 31 4.6 11.8 2.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter F-box PF00646.33 GAN03141.1 - 0.0027 17.5 0.2 0.0027 17.5 0.2 1.9 2 0 0 2 2 2 1 F-box domain PK PF00224.21 GAN03142.1 - 5.3e-170 564.9 4.3 6.6e-170 564.6 4.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAN03142.1 - 1.6e-41 141.2 0.0 3.6e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DAHP_snth_FXD PF18152.1 GAN03142.1 - 0.0002 21.1 0.6 0.0006 19.6 0.1 2.1 2 0 0 2 2 2 1 DAHP synthase ferredoxin-like domain HpcH_HpaI PF03328.14 GAN03142.1 - 0.0036 16.5 0.1 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 GAN03142.1 - 0.008 15.2 0.0 0.072 12.1 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 GAN03142.1 - 0.034 13.6 0.1 0.085 12.3 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Chitin_synth_2 PF03142.15 GAN03143.1 - 6.4e-214 711.4 0.1 9e-214 710.9 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAN03143.1 - 6.4e-15 55.7 0.0 2.9e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN03143.1 - 3.8e-10 40.0 6.4 3.8e-10 40.0 6.4 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GAN03143.1 - 1.9e-05 24.2 0.1 0.00058 19.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAN03143.1 - 0.0022 17.8 0.0 0.081 12.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2730 PF10805.8 GAN03144.1 - 0.017 15.2 10.5 0.14 12.2 4.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) FMO-like PF00743.19 GAN03144.1 - 0.16 10.4 0.2 0.28 9.6 0.2 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like SepSecS PF05889.13 GAN03144.1 - 0.47 9.1 3.9 0.18 10.4 0.4 1.8 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF883 PF05957.13 GAN03144.1 - 1.6 9.4 8.0 6.5 7.4 0.2 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) APG12 PF04110.13 GAN03145.1 - 5e-34 116.6 0.0 6.5e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 GAN03145.1 - 0.00015 21.9 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GAD-like PF08887.11 GAN03145.1 - 0.084 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain FR47 PF08445.10 GAN03147.1 - 6.6e-08 32.4 0.1 6.3e-07 29.3 0.1 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 GAN03147.1 - 8.9e-05 22.7 0.1 0.00037 20.7 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN03147.1 - 0.0006 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN03147.1 - 0.0027 17.6 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Arf PF00025.21 GAN03147.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family FbpA PF05833.11 GAN03148.1 - 5.8e-41 140.7 15.6 5.8e-41 140.7 15.6 2.9 3 0 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 GAN03148.1 - 2e-32 112.1 0.0 6.4e-32 110.5 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 GAN03148.1 - 8.9e-31 106.0 0.1 8.9e-31 106.0 0.1 4.8 4 1 1 5 5 5 1 NFACT protein C-terminal domain AF-4 PF05110.13 GAN03148.1 - 0.00012 20.4 36.7 0.00012 20.4 36.7 2.1 2 0 0 2 2 2 1 AF-4 proto-oncoprotein SUIM_assoc PF16619.5 GAN03148.1 - 9.1 6.4 14.4 3 8.0 3.5 4.1 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 eIF-3c_N PF05470.12 GAN03149.1 - 2.1e-33 115.5 11.1 2.1e-33 115.5 11.1 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PSII_Pbs27 PF13326.6 GAN03149.1 - 0.0031 17.8 2.7 0.0048 17.2 2.7 1.6 1 1 0 1 1 1 1 Photosystem II Pbs27 HemX PF04375.14 GAN03149.1 - 0.071 12.4 12.4 0.039 13.3 5.3 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase YkyA PF10368.9 GAN03149.1 - 0.68 9.6 19.0 1.4 8.5 17.6 2.0 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Peptidase_S64 PF08192.11 GAN03149.1 - 0.77 8.2 12.9 0.99 7.8 12.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF724 PF05266.14 GAN03149.1 - 3.2 7.5 16.4 0.2 11.4 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) eIF-3c_N PF05470.12 GAN03150.1 - 5.9e-146 487.2 0.3 1.1e-145 486.4 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GAN03150.1 - 9.3e-16 58.2 0.0 2.7e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain CHASE3 PF05227.13 GAN03150.1 - 1.3 8.9 7.7 1.5 8.7 0.2 3.1 4 0 0 4 4 4 0 CHASE3 domain EMP24_GP25L PF01105.24 GAN03151.1 - 4.3e-53 180.0 2.0 5.1e-53 179.7 2.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD End3 PF12761.7 GAN03151.1 - 0.0087 16.2 0.8 0.013 15.7 0.8 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 CrgA PF06781.12 GAN03151.1 - 0.078 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Cell division protein CrgA DUF4337 PF14235.6 GAN03151.1 - 0.1 12.7 0.4 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PPC PF04151.15 GAN03151.1 - 0.1 13.7 0.9 0.15 13.2 0.2 1.6 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Acetyltransf_3 PF13302.7 GAN03152.1 - 1.6e-15 58.0 0.0 2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN03152.1 - 0.091 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pex16 PF08610.10 GAN03153.1 - 1.4e-63 215.0 0.5 2.4e-63 214.3 0.5 1.3 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) WHEP-TRS PF00458.20 GAN03154.1 - 0.0011 19.0 4.1 0.0011 19.0 4.1 1.5 1 1 0 1 1 1 1 WHEP-TRS domain DUF16 PF01519.16 GAN03154.1 - 0.15 12.6 5.0 0.17 12.4 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 WHEP-TRS PF00458.20 GAN03155.1 - 0.00084 19.5 1.4 0.00084 19.5 1.4 1.9 2 0 0 2 2 2 1 WHEP-TRS domain ZapD PF07072.11 GAN03155.1 - 0.021 14.6 2.5 0.021 14.6 2.5 1.1 1 0 0 1 1 1 0 Cell division protein DUF641 PF04859.12 GAN03155.1 - 0.034 14.5 4.7 0.039 14.3 4.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2968 PF11180.8 GAN03155.1 - 0.035 13.7 7.3 0.035 13.7 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ADIP PF11559.8 GAN03155.1 - 0.038 14.1 6.6 0.047 13.8 6.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CP12 PF02672.15 GAN03155.1 - 0.065 14.0 0.1 0.065 14.0 0.1 1.5 2 0 0 2 2 2 0 CP12 domain DUF16 PF01519.16 GAN03155.1 - 0.15 12.6 7.0 0.23 12.0 7.0 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 GAN03155.1 - 0.45 9.8 5.4 0.46 9.8 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 GAN03155.1 - 0.65 10.3 6.3 0.82 10.0 6.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3573 PF12097.8 GAN03155.1 - 0.68 8.7 4.7 0.7 8.7 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Thiolase_N PF00108.23 GAN03156.1 - 3.2e-78 262.7 5.3 5.8e-78 261.8 4.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN03156.1 - 2.9e-47 159.3 0.1 5.2e-47 158.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain Mo25 PF08569.11 GAN03157.1 - 6.1e-142 472.8 14.6 7.1e-142 472.6 14.6 1.0 1 0 0 1 1 1 1 Mo25-like Lipocalin_7 PF14651.6 GAN03157.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family GYF PF02213.16 GAN03158.1 - 3.4e-18 65.0 0.9 1.6e-17 62.9 0.3 2.2 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 GAN03158.1 - 0.003 17.3 0.1 0.01 15.6 0.1 2.0 1 0 0 1 1 1 1 GYF domain 2 Glyco_hydro_16 PF00722.21 GAN03159.1 - 1.1e-10 41.3 0.2 2.1e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 GAN03160.1 - 1.3e-66 224.7 0.0 9.2e-65 218.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03160.1 - 4.2e-33 114.7 0.0 5.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN03160.1 - 0.0001 21.7 0.1 0.00021 20.7 0.1 1.6 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GAN03160.1 - 0.019 14.6 0.2 0.67 9.5 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAN03160.1 - 0.063 12.2 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAN03160.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN03160.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 GAN03161.1 - 2.3e-95 320.1 24.3 1.5e-48 165.8 14.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN03161.1 - 2.7e-23 82.5 25.9 2.7e-21 75.9 15.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.6 GAN03161.1 - 5.4 6.7 6.5 1.9 8.1 2.5 2.2 2 0 0 2 2 2 0 Kinocilin protein DUF1385 PF07136.11 GAN03161.1 - 7.2 5.8 10.8 7.4 5.8 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Ribonuc_red_sm PF00268.21 GAN03162.1 - 6.9e-116 386.6 2.2 1e-115 386.0 2.2 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.21 GAN03163.1 - 2.6e-117 391.3 2.5 3.1e-117 391.0 2.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CRAL_TRIO PF00650.20 GAN03164.1 - 7.8e-24 84.2 0.0 1.2e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN03164.1 - 7.4e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_transf_15 PF01793.16 GAN03165.1 - 4.8e-118 394.1 16.5 5.8e-118 393.8 16.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Filament PF00038.21 GAN03166.1 - 0.004 16.8 9.6 0.004 16.8 9.6 1.6 2 0 0 2 2 2 1 Intermediate filament protein Not3 PF04065.15 GAN03166.1 - 0.016 14.7 18.1 0.18 11.2 11.3 3.1 2 1 1 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component NPV_P10 PF05531.12 GAN03166.1 - 0.019 15.4 5.3 0.079 13.4 1.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Plasmid_RAQPRD PF09686.10 GAN03166.1 - 0.029 14.6 4.7 0.046 13.9 0.6 3.2 1 1 2 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TetR_C_13 PF16925.5 GAN03166.1 - 0.1 12.6 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FlaC_arch PF05377.11 GAN03166.1 - 0.1 13.0 2.5 5.3 7.5 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lzipper-MIP1 PF14389.6 GAN03166.1 - 0.2 12.0 4.4 0.82 10.0 2.0 3.3 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF948 PF06103.11 GAN03166.1 - 0.22 11.8 3.3 5.3 7.4 0.5 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ROK PF00480.20 GAN03166.1 - 0.27 10.7 2.6 0.33 10.4 0.6 2.0 1 1 1 2 2 2 0 ROK family TPR_MLP1_2 PF07926.12 GAN03166.1 - 0.57 10.2 13.4 0.065 13.3 2.7 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DNA_repr_REX1B PF14966.6 GAN03166.1 - 0.6 10.8 6.1 2.9 8.6 5.1 2.7 2 1 0 2 2 2 0 DNA repair REX1-B LPP PF04728.13 GAN03166.1 - 0.76 10.2 4.7 20 5.6 0.1 3.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Laminin_II PF06009.12 GAN03166.1 - 4.3 7.4 8.6 25 4.9 5.9 2.9 2 1 0 2 2 2 0 Laminin Domain II Sec20 PF03908.13 GAN03166.1 - 6 6.9 7.7 6.9 6.7 0.4 3.4 3 1 0 4 4 4 0 Sec20 Ribosomal_60s PF00428.19 GAN03167.1 - 7.6e-25 87.3 12.6 8.8e-25 87.1 12.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein TetR_C_31 PF17940.1 GAN03167.1 - 0.036 14.3 0.9 0.046 13.9 0.9 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MAGE_N PF12440.8 GAN03167.1 - 0.081 13.6 5.1 0.097 13.4 5.1 1.1 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal RNF220 PF15926.5 GAN03168.1 - 0.051 13.2 3.9 0.09 12.4 3.9 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Glyco_transf_22 PF03901.17 GAN03171.1 - 6e-39 134.4 29.0 8.4e-39 134.0 29.0 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glutaredoxin PF00462.24 GAN03171.1 - 1.8e-15 56.9 0.1 4.1e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 GAN03171.1 - 0.011 16.2 0.1 0.024 15.0 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF5534 PF17686.1 GAN03171.1 - 0.71 10.1 2.5 7.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5534) Arrestin_C PF02752.22 GAN03172.1 - 1.3e-06 28.9 4.1 0.0003 21.2 1.0 3.0 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN03172.1 - 0.002 18.2 0.0 0.0071 16.4 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DNA_pol3_tau_5 PF12170.8 GAN03172.1 - 0.24 11.4 1.7 0.46 10.5 0.3 2.1 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha TFIIA PF03153.13 GAN03172.1 - 6 6.8 9.4 14 5.5 9.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRP38 PF03371.15 GAN03173.1 - 2.3e-55 187.2 0.5 2.3e-55 187.2 0.5 1.8 2 0 0 2 2 2 1 PRP38 family Pkinase PF00069.25 GAN03173.1 - 1.6e-28 99.8 0.4 6.3e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03173.1 - 6.3e-12 45.3 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN03173.1 - 4.8e-10 38.8 1.4 5.9e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase SUIM_assoc PF16619.5 GAN03173.1 - 0.0039 17.2 3.6 0.0039 17.2 3.6 2.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF1840 PF08895.11 GAN03173.1 - 0.076 13.3 0.3 0.2 12.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) TFIIA PF03153.13 GAN03173.1 - 0.43 10.5 14.3 0.67 9.9 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAN03173.1 - 1 8.9 16.9 2.2 7.9 16.9 1.5 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 GAN03173.1 - 2.7 9.0 8.3 9.9 7.2 8.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 GAN03173.1 - 4 6.1 4.8 6.1 5.5 4.8 1.2 1 0 0 1 1 1 0 Presenilin F-box-like PF12937.7 GAN03174.1 - 5.3e-08 32.6 0.4 1.4e-07 31.3 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03174.1 - 0.0023 17.8 0.1 0.0093 15.8 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAN03174.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 F-box PPR_2 PF13041.6 GAN03175.1 - 2.2e-54 181.4 20.9 2e-12 47.1 0.1 8.4 3 1 5 8 8 8 8 PPR repeat family PPR_3 PF13812.6 GAN03175.1 - 4.3e-42 142.0 9.8 5.8e-13 48.7 0.0 5.6 5 0 0 5 5 5 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAN03175.1 - 8.5e-37 124.5 0.1 1.4e-07 31.1 0.0 8.6 9 0 0 9 9 9 6 PPR repeat PPR PF01535.20 GAN03175.1 - 1.7e-35 118.8 5.1 5.1e-05 23.2 0.1 8.7 9 0 0 9 9 9 6 PPR repeat PPR_long PF17177.4 GAN03175.1 - 1.2e-23 83.6 1.4 1.4e-09 37.6 0.5 3.2 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAN03175.1 - 1e-05 25.9 9.8 0.047 14.1 0.1 5.7 5 2 1 6 6 6 2 Mitochondrial ribonuclease P subunit (RPM2) DNA_pol_phi PF04931.13 GAN03175.1 - 0.0013 17.0 0.1 0.0027 15.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase phi MRP-S27 PF10037.9 GAN03175.1 - 0.0054 15.6 1.4 0.018 13.9 0.9 2.0 1 1 1 2 2 2 1 Mitochondrial 28S ribosomal protein S27 Alb1 PF09135.11 GAN03175.1 - 2.2 9.2 7.1 4.6 8.2 6.5 1.9 1 1 1 2 2 2 0 Alb1 Csm1_N PF18504.1 GAN03176.1 - 0.062 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain Cep57_CLD_2 PF14197.6 GAN03176.1 - 0.078 13.1 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 GAN03176.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor Ndc80_HEC PF03801.13 GAN03177.1 - 6.3e-29 100.6 0.1 1.5e-28 99.3 0.1 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family LPP PF04728.13 GAN03177.1 - 2.8 8.4 9.7 0.77 10.2 1.1 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper OmpH PF03938.14 GAN03177.1 - 4.2 7.7 46.5 0.31 11.4 1.7 4.2 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF5082 PF16888.5 GAN03177.1 - 7.3 6.9 31.3 1.5 9.1 7.1 4.9 1 1 2 4 4 4 0 Domain of unknown function (DUF5082) SNF2_N PF00176.23 GAN03178.1 - 2.7e-67 227.0 0.0 1.3e-66 224.7 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN03178.1 - 2.9e-20 72.7 0.0 7.3e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 GAN03178.1 - 9.2e-17 60.8 0.0 1.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_3 PF13920.6 GAN03178.1 - 1.6e-07 31.0 8.8 3.1e-07 30.1 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN03178.1 - 1.6e-06 28.4 10.3 3.9e-06 27.1 10.3 1.7 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.29 GAN03178.1 - 1.2e-05 25.1 0.0 3.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAN03178.1 - 2.8e-05 24.2 0.0 0.0001 22.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA_4 PF14555.6 GAN03178.1 - 0.00027 20.7 0.1 0.00064 19.5 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain zf-RING_5 PF14634.6 GAN03178.1 - 0.00038 20.3 10.6 0.00078 19.4 10.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAN03178.1 - 0.00058 19.7 10.3 0.0012 18.7 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN03178.1 - 0.0025 17.8 5.3 0.0025 17.8 5.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger CUE PF02845.16 GAN03178.1 - 0.0066 16.1 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain zf-C3HC4_2 PF13923.6 GAN03178.1 - 0.0099 15.7 11.8 0.026 14.4 11.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Josephin PF02099.17 GAN03178.1 - 0.12 12.5 0.2 0.37 10.9 0.2 1.8 1 0 0 1 1 1 0 Josephin Prok-RING_4 PF14447.6 GAN03178.1 - 0.17 11.8 10.1 0.35 10.8 10.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAN03178.1 - 4.3 7.6 12.6 8.8 6.6 12.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Acyltransferase PF01553.21 GAN03179.1 - 4.1e-09 36.2 0.0 2.1e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Metallophos PF00149.28 GAN03180.1 - 3.2e-30 106.1 0.1 5.2e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 GAN03180.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) XRN_M PF17846.1 GAN03181.1 - 8.8e-152 506.1 2.4 2.4e-149 498.1 2.4 2.2 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 GAN03181.1 - 6.6e-101 336.8 1.9 9.2e-101 336.3 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 GAN03181.1 - 0.0015 18.6 3.0 0.0029 17.6 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 GAN03181.1 - 0.26 9.6 9.9 0.53 8.5 9.9 1.4 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC_3 PF13917.6 GAN03181.1 - 0.26 11.3 5.0 0.11 12.5 2.2 1.8 2 0 0 2 2 2 0 Zinc knuckle RXT2_N PF08595.11 GAN03181.1 - 6.1 6.8 11.6 3.4 7.7 8.3 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.12 GAN03181.1 - 6.8 4.8 21.4 11 4.1 21.4 1.2 1 0 0 1 1 1 0 Nop14-like family T2SSI PF02501.17 GAN03183.1 - 0.56 10.4 7.0 2.4 8.4 7.0 2.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Glyco_hydro_15 PF00723.21 GAN03184.1 - 8.8e-67 225.8 0.0 1.3e-66 225.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RNase_T PF00929.24 GAN03185.1 - 6.1e-12 46.4 0.0 1.1e-11 45.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAN03185.1 - 0.022 14.5 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 0 3'-5' exonuclease CSRNP_N PF16019.5 GAN03185.1 - 3.9 7.3 11.0 8 6.3 2.0 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus ING PF12998.7 GAN03186.1 - 2.9e-17 63.1 7.9 4e-17 62.7 7.9 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAN03186.1 - 1.8e-06 27.7 8.3 3.2e-06 26.9 8.3 1.4 1 0 0 1 1 1 1 PHD-finger HEPN-like_int PF18867.1 GAN03186.1 - 0.0045 16.9 0.3 0.0071 16.2 0.3 1.3 1 0 0 1 1 1 1 HEPN-like integron domain GrpE PF01025.19 GAN03186.1 - 0.014 15.1 2.3 0.019 14.6 2.3 1.1 1 0 0 1 1 1 0 GrpE PHD_2 PF13831.6 GAN03186.1 - 0.018 14.6 1.8 0.034 13.7 1.8 1.5 1 0 0 1 1 1 0 PHD-finger CENP-Q PF13094.6 GAN03186.1 - 0.054 13.7 3.9 0.078 13.2 3.9 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-HC5HC2H PF13771.6 GAN03186.1 - 0.095 13.0 3.5 0.098 12.9 2.1 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain FapA PF03961.13 GAN03186.1 - 0.12 11.0 1.6 0.15 10.6 1.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dam1 PF08653.10 GAN03186.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Jnk-SapK_ap_N PF09744.9 GAN03186.1 - 0.57 10.4 6.5 0.88 9.8 6.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FliD_N PF02465.18 GAN03186.1 - 0.6 10.8 5.4 2.1 9.1 0.8 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 GAN03186.1 - 2.7 8.2 7.2 5.9 7.1 7.2 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Amidase PF01425.21 GAN03187.1 - 1.8e-89 300.8 0.0 3e-89 300.0 0.0 1.4 1 1 0 1 1 1 1 Amidase HipN PF18253.1 GAN03187.1 - 0.0026 17.4 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain SOBP PF15279.6 GAN03188.1 - 0.036 14.7 8.9 0.043 14.4 8.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Thioredoxin PF00085.20 GAN03189.1 - 1.4e-27 95.7 0.2 1.6e-27 95.5 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAN03189.1 - 9.9e-06 26.0 0.2 0.00037 20.9 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAN03189.1 - 6e-05 22.8 0.0 7.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 GAN03189.1 - 6.5e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GAN03189.1 - 0.00026 20.9 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 GAN03189.1 - 0.00041 20.6 0.0 0.00099 19.4 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAN03189.1 - 0.0012 18.8 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 GAN03189.1 - 0.011 15.1 0.1 0.012 15.0 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phosducin PF02114.16 GAN03189.1 - 0.041 12.8 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Phosducin Nic96 PF04097.14 GAN03190.1 - 6.4e-104 348.6 6.8 6.4e-104 348.6 6.8 1.4 2 0 0 2 2 2 1 Nup93/Nic96 DUF1217 PF06748.12 GAN03190.1 - 0.01 15.9 0.0 0.23 11.5 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1217) Kelch_4 PF13418.6 GAN03191.1 - 1.7e-11 43.9 11.4 0.00031 20.7 0.1 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN03191.1 - 7.4e-08 32.2 5.4 0.026 14.5 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 GAN03191.1 - 4.2e-07 30.0 7.5 0.012 15.9 0.2 4.8 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.6 GAN03191.1 - 9.2e-05 22.6 0.2 9.2e-05 22.6 0.2 4.9 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN03191.1 - 0.00019 21.3 3.9 0.11 12.5 0.2 4.4 5 0 0 5 5 5 1 Kelch motif Peptidase_S32 PF05579.13 GAN03191.1 - 0.038 13.2 0.3 0.07 12.3 0.3 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 TPP_enzyme_N PF02776.18 GAN03192.1 - 1.4e-28 99.6 0.0 3e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAN03192.1 - 6.8e-19 68.2 0.0 1.3e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAN03192.1 - 2.5e-18 66.2 0.0 4.7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 GAN03192.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TRAM_LAG1_CLN8 PF03798.16 GAN03193.1 - 3e-42 144.6 26.3 3e-42 144.6 26.3 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAN03193.1 - 5.2e-17 61.3 1.2 2.5e-16 59.1 1.2 2.3 1 0 0 1 1 1 1 TRAM1-like protein IGPD PF00475.18 GAN03194.1 - 2.6e-62 209.4 0.6 3.5e-62 209.0 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PCP PF02429.15 GAN03194.1 - 0.064 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein DUF1005 PF06219.12 GAN03195.1 - 0.091 11.8 0.1 0.086 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) adh_short_C2 PF13561.6 GAN03196.1 - 3.3e-52 177.4 3.3 1e-42 146.3 1.6 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN03196.1 - 2.3e-46 157.7 1.8 2.8e-46 157.5 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN03196.1 - 7.1e-15 55.4 0.4 1.1e-14 54.8 0.4 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 GAN03196.1 - 1.3e-05 25.3 0.2 2.1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 GAN03196.1 - 0.0076 16.2 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pribosyltran PF00156.27 GAN03197.1 - 5.2e-07 29.3 0.0 7.2e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain KTI12 PF08433.10 GAN03198.1 - 6.3e-94 314.4 0.0 7e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAN03198.1 - 9.5e-09 35.6 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN03198.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 GAN03198.1 - 0.018 15.6 0.0 0.049 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAN03198.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AhpC-TSA PF00578.21 GAN03199.1 - 4e-38 130.1 0.0 1.8e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAN03199.1 - 3.2e-15 56.1 0.0 4.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAN03199.1 - 3.3e-13 49.2 0.1 6.5e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin HAGH_C PF16123.5 GAN03200.1 - 1.1e-25 89.9 0.0 1.6e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAN03200.1 - 1.3e-09 38.4 3.8 4.9e-08 33.2 3.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN03200.1 - 0.00062 19.3 0.2 0.0094 15.5 0.2 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain 4HBT_2 PF13279.6 GAN03201.1 - 1.9e-12 47.7 0.1 5.9e-12 46.1 0.2 1.7 2 1 0 2 2 2 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 GAN03201.1 - 0.0017 17.7 0.3 0.0017 17.7 0.3 1.5 2 0 0 2 2 2 1 Acyl-ACP thioesterase SL4P PF17618.2 GAN03201.1 - 0.1 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Pkinase PF00069.25 GAN03202.1 - 5.3e-76 255.5 0.0 1.2e-75 254.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03202.1 - 3.3e-37 128.2 0.0 9e-37 126.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4763 PF15960.5 GAN03202.1 - 0.00045 19.6 3.8 0.00096 18.5 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Kinase-like PF14531.6 GAN03202.1 - 0.0011 18.3 0.8 0.27 10.5 0.0 3.1 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 GAN03202.1 - 0.0012 17.7 0.8 0.013 14.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase RXT2_N PF08595.11 GAN03202.1 - 0.0093 16.0 5.2 0.026 14.5 5.2 1.7 1 0 0 1 1 1 1 RXT2-like, N-terminal PhzC-PhzF PF02567.16 GAN03202.1 - 0.085 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein APH PF01636.23 GAN03202.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GDA1_CD39 PF01150.17 GAN03203.1 - 2.1e-99 333.1 0.0 2.7e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family WH1 PF00568.23 GAN03206.1 - 5.3e-08 32.8 0.1 7.1e-05 22.7 0.0 2.2 1 1 0 2 2 2 2 WH1 domain Sel1 PF08238.12 GAN03207.1 - 8.4e-51 169.3 17.1 5.1e-09 36.5 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat Pkinase PF00069.25 GAN03208.1 - 2.3e-69 233.7 0.0 2.9e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03208.1 - 1.7e-29 102.9 0.0 2.7e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cofac_haem_bdg PF04187.13 GAN03208.1 - 0.01 15.8 0.0 5.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Haspin_kinase PF12330.8 GAN03208.1 - 0.013 14.4 1.5 0.021 13.8 0.0 1.9 2 1 0 2 2 2 0 Haspin like kinase domain zf-Nse PF11789.8 GAN03208.1 - 0.056 13.3 0.7 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit APH PF01636.23 GAN03208.1 - 0.1 12.5 0.1 0.53 10.2 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN03208.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ins_beta PF03488.14 GAN03208.1 - 2.9 8.0 4.7 3.3 7.8 0.2 2.9 4 0 0 4 4 4 0 Nematode insulin-related peptide beta type Filaggrin PF03516.13 GAN03208.1 - 3.2 8.5 8.8 5.9 7.7 8.8 1.4 1 0 0 1 1 1 0 Filaggrin RasGAP PF00616.19 GAN03209.1 - 7.3e-48 163.0 0.1 7.3e-48 163.0 0.1 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAN03209.1 - 4.1e-40 137.1 1.8 4.1e-40 137.1 1.8 3.4 4 0 0 4 4 4 1 RasGAP C-terminus CH PF00307.31 GAN03209.1 - 5.4e-15 55.5 0.1 2e-14 53.7 0.1 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 GAN03209.1 - 8.8e-11 40.6 4.3 0.0013 18.4 0.3 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif HEAT PF02985.22 GAN03210.1 - 3.6e-44 145.0 22.8 0.00046 20.2 0.0 13.9 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 GAN03210.1 - 1.3e-35 121.6 12.1 5.2e-09 36.4 0.0 7.4 3 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 GAN03210.1 - 1.1e-10 42.0 0.3 0.78 10.4 0.0 6.5 3 2 5 8 8 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN03210.1 - 4.6e-10 39.8 10.5 0.0023 18.0 0.6 5.5 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAN03210.1 - 1e-07 31.0 9.8 0.00021 20.0 1.5 4.0 2 1 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 GAN03210.1 - 4.1e-07 30.4 12.7 0.092 13.3 0.1 8.2 9 1 1 10 10 10 2 HEAT-like repeat RTP1_C1 PF10363.9 GAN03210.1 - 1.1e-06 28.7 7.1 0.41 10.8 0.0 5.5 3 2 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 GAN03210.1 - 5.5e-05 23.0 0.7 0.0033 17.2 0.0 3.1 2 1 0 2 2 2 1 DNA alkylation repair enzyme M11L PF11099.8 GAN03210.1 - 0.011 16.1 0.5 8.9 6.6 0.0 3.2 2 1 0 2 2 2 0 Apoptosis regulator M11L like HEAT_PBS PF03130.16 GAN03210.1 - 0.094 13.4 0.7 4.4 8.3 0.0 4.3 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 GAN03210.1 - 0.27 11.3 4.2 13 6.0 0.0 5.5 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 GAN03210.1 - 0.44 10.9 2.2 5.2 7.5 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion LRV PF01816.17 GAN03210.1 - 1.7 9.2 5.0 3.3e+02 2.0 0.1 5.6 5 0 0 5 5 4 0 Leucine rich repeat variant Abhydrolase_1 PF00561.20 GAN03212.1 - 2.7e-30 105.9 0.0 9e-30 104.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN03212.1 - 1.8e-21 76.5 0.0 3.1e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN03212.1 - 3.7e-17 63.7 0.0 5.7e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAN03212.1 - 8.8e-07 29.0 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 GAN03212.1 - 1.7e-06 27.9 0.1 4.9e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 GAN03212.1 - 1.7e-05 24.8 0.0 7e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 GAN03212.1 - 4.3e-05 22.3 0.0 0.00019 20.2 0.0 1.9 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 GAN03212.1 - 0.0001 22.1 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family LIDHydrolase PF10230.9 GAN03212.1 - 0.00013 21.6 0.0 0.00036 20.2 0.0 1.7 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 GAN03212.1 - 0.00017 21.8 0.3 0.026 14.6 0.3 3.0 2 1 0 2 2 2 1 Thioesterase domain UPF0227 PF05728.12 GAN03212.1 - 0.00038 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 GAN03212.1 - 0.0027 17.6 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) BAAT_C PF08840.11 GAN03212.1 - 0.013 15.5 0.0 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 GAN03212.1 - 0.028 13.3 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_8 PF06259.12 GAN03212.1 - 0.063 12.9 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF676 PF05057.14 GAN03212.1 - 0.067 12.7 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 GAN03212.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 GAN03212.1 - 0.11 12.3 0.0 1.4 8.6 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase YjeF_N PF03853.15 GAN03213.1 - 2.8e-32 111.9 0.0 2.8e-32 111.9 0.0 2.2 2 0 0 2 2 2 1 YjeF-related protein N-terminus LSM PF01423.22 GAN03213.1 - 0.0032 17.1 0.2 0.0062 16.2 0.2 1.5 1 0 0 1 1 1 1 LSM domain Pep3_Vps18 PF05131.14 GAN03214.1 - 2.8e-49 166.8 0.1 9e-49 165.1 0.1 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 GAN03214.1 - 6.3e-09 35.8 14.1 4.7e-06 26.5 3.1 3.6 4 1 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 GAN03214.1 - 6e-05 23.5 0.6 0.00021 21.7 0.6 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.9 GAN03214.1 - 0.0044 17.3 0.7 0.019 15.2 0.7 2.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 GAN03214.1 - 0.0054 16.3 2.1 0.0054 16.3 2.1 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 GAN03214.1 - 0.0066 16.8 2.5 0.0066 16.8 2.5 2.2 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 GAN03214.1 - 0.056 13.7 0.5 0.19 12.1 0.5 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAN03214.1 - 0.076 12.9 4.0 0.27 11.1 4.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sigma70_r1_1 PF03979.14 GAN03214.1 - 0.084 12.9 0.9 0.22 11.6 0.9 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 zf-RING_11 PF17123.5 GAN03214.1 - 0.11 12.2 5.5 0.4 10.5 5.5 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 GAN03214.1 - 0.22 11.5 3.8 0.89 9.6 3.8 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Zf_RING PF16744.5 GAN03214.1 - 0.27 11.4 5.7 0.1 12.7 1.7 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger TPR_8 PF13181.6 GAN03214.1 - 0.7 10.3 4.6 45 4.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3H2C3 PF17122.5 GAN03214.1 - 6.4 6.9 10.2 0.65 10.1 5.2 2.0 2 0 0 2 2 2 0 Zinc-finger Colicin_im PF03857.13 GAN03215.1 - 0.17 11.8 3.7 0.23 11.4 3.7 1.2 1 0 0 1 1 1 0 Colicin immunity protein ABC2_membrane_3 PF12698.7 GAN03215.1 - 4 6.5 9.3 5 6.1 9.3 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein RasGAP PF00616.19 GAN03216.1 - 6.7e-39 133.8 2.3 7.8e-39 133.5 0.4 2.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAN03216.1 - 2e-38 131.6 0.5 5.9e-38 130.1 0.0 2.1 2 0 0 2 2 2 1 RasGAP C-terminus RNase_PH PF01138.21 GAN03216.1 - 1.1e-20 74.5 1.0 2.2e-20 73.5 0.1 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAN03216.1 - 4.1e-06 26.7 0.0 2.3e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF4047 PF13256.6 GAN03216.1 - 0.071 13.3 0.2 0.29 11.3 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF3800 PF12686.7 GAN03216.1 - 0.88 10.2 4.2 14 6.4 4.2 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) YabA PF06156.13 GAN03216.1 - 2.5 8.8 7.0 10 6.8 0.3 3.4 3 0 0 3 3 3 0 Initiation control protein YabA KASH_CCD PF14662.6 GAN03216.1 - 5.2 6.8 9.3 8.6 6.1 2.2 2.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Syntaxin-6_N PF09177.11 GAN03218.1 - 4.8e-25 88.0 7.0 1.7e-24 86.2 4.3 2.7 2 0 0 2 2 2 1 Syntaxin 6, N-terminal PhoLip_ATPase_N PF16209.5 GAN03218.1 - 1.4e-09 37.5 2.1 3.3e-09 36.3 2.1 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal CENP-Q PF13094.6 GAN03218.1 - 0.0013 18.9 5.2 0.0035 17.6 5.2 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Duo1 PF08651.10 GAN03218.1 - 0.0079 16.0 2.7 0.89 9.4 0.2 3.0 2 0 0 2 2 2 1 DASH complex subunit Duo1 SNARE PF05739.19 GAN03218.1 - 0.01 15.8 1.1 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 SNARE domain Flg_hook PF02120.16 GAN03218.1 - 0.014 15.3 0.6 0.041 13.8 0.6 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK ABC_tran_CTD PF16326.5 GAN03218.1 - 0.036 14.3 2.5 0.13 12.5 2.5 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain FliJ PF02050.16 GAN03218.1 - 0.058 13.6 9.3 2.4 8.4 2.1 2.9 2 0 0 2 2 2 0 Flagellar FliJ protein Sugarporin_N PF11471.8 GAN03218.1 - 0.085 12.8 2.8 0.19 11.7 2.8 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension CorA PF01544.18 GAN03218.1 - 0.3 10.4 4.4 0.18 11.1 0.2 2.4 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein THOC7 PF05615.13 GAN03218.1 - 0.3 11.3 4.7 0.7 10.2 3.1 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 GAS PF13851.6 GAN03218.1 - 0.38 10.1 9.2 0.032 13.6 3.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 GAN03218.1 - 0.89 9.8 3.4 30 4.9 0.1 2.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF745 PF05335.13 GAN03218.1 - 1.2 8.8 9.2 5.7 6.6 2.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF745) CRR7 PF12095.8 GAN03218.1 - 3.3 8.2 7.9 71 3.9 0.1 3.5 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Laminin_II PF06009.12 GAN03218.1 - 6.2 6.8 10.5 2.1 8.4 4.4 2.6 2 0 0 2 2 2 0 Laminin Domain II PhoLip_ATPase_C PF16212.5 GAN03219.1 - 5.5e-84 281.8 27.6 5.5e-84 281.8 27.6 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 GAN03219.1 - 1.1e-13 51.1 0.0 9.1e-13 48.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN03219.1 - 2.4e-12 47.6 0.2 1.2e-05 25.7 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN03219.1 - 0.0019 18.0 0.4 0.011 15.5 0.1 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribonuclease_T2 PF00445.18 GAN03220.1 - 6e-35 121.1 0.4 7.7e-35 120.8 0.4 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family TFIID-31kDa PF02291.15 GAN03221.1 - 2.8e-50 169.5 0.0 3.6e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN03221.1 - 1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 GAN03221.1 - 0.00036 20.9 0.0 0.00067 20.0 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAN03221.1 - 0.0025 18.2 0.0 0.0036 17.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID_30kDa PF03540.13 GAN03221.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit CTP_transf_like PF01467.26 GAN03222.1 - 1.7e-44 151.5 0.1 8.7e-27 94.1 0.0 2.3 2 1 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 GAN03222.1 - 9.1e-05 22.4 0.4 0.53 10.2 0.0 2.8 3 0 0 3 3 3 2 FAD synthetase CoA_binding_3 PF13727.6 GAN03222.1 - 0.0083 16.2 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 CoA-binding domain ScdA_N PF04405.14 GAN03222.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) Pantoate_ligase PF02569.15 GAN03222.1 - 0.017 14.4 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Peptidase_C80 PF11713.8 GAN03222.1 - 0.06 13.6 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase C80 family Arrestin_C PF02752.22 GAN03223.1 - 9.1e-11 42.3 2.9 1.3e-09 38.7 0.3 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN03223.1 - 0.033 14.2 0.0 5.7 7.0 0.0 3.0 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Rer1 PF03248.13 GAN03224.1 - 2.7e-65 219.3 6.5 4.7e-65 218.5 6.5 1.3 1 0 0 1 1 1 1 Rer1 family NUDIX PF00293.28 GAN03224.1 - 2.1e-11 44.0 0.0 4.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain PAP2_3 PF14378.6 GAN03225.1 - 4.7e-22 78.6 11.5 4.7e-22 78.6 11.5 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 GAN03225.1 - 1.1e-07 31.7 3.2 1.1e-07 31.7 3.2 2.4 2 1 1 3 3 3 1 PAP2 superfamily DUF1129 PF06570.11 GAN03225.1 - 2.1 7.8 4.2 0.87 9.0 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) LTV PF04180.14 GAN03226.1 - 5.3e-85 286.4 27.2 5.3e-85 286.4 27.2 3.0 1 1 2 3 3 3 2 Low temperature viability protein TUDOR_5 PF18359.1 GAN03226.1 - 0.026 14.2 0.5 0.055 13.2 0.5 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 TPR_MLP1_2 PF07926.12 GAN03227.1 - 0.015 15.4 10.4 0.015 15.4 10.4 4.9 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein OmpH PF03938.14 GAN03227.1 - 0.017 15.5 11.7 0.017 15.5 11.7 5.2 3 2 1 4 4 4 0 Outer membrane protein (OmpH-like) CorA PF01544.18 GAN03227.1 - 2.7 7.2 24.9 0.12 11.7 1.7 3.4 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 GAN03227.1 - 3.4 7.7 7.8 1.6 8.7 3.2 2.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 GAN03227.1 - 7.8 6.6 12.2 0.56 10.3 2.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) AAA_13 PF13166.6 GAN03228.1 - 0.0014 17.4 32.2 0.0014 17.4 32.2 9.4 2 1 7 10 10 10 4 AAA domain HEAT_2 PF13646.6 GAN03229.1 - 9.1e-25 86.9 1.2 1.6e-06 28.4 0.0 7.7 6 2 2 8 8 8 3 HEAT repeats HEAT PF02985.22 GAN03229.1 - 9.5e-24 81.4 12.0 2.3e-05 24.3 0.2 10.8 12 0 0 12 12 11 4 HEAT repeat HEAT_EZ PF13513.6 GAN03229.1 - 1.4e-20 73.4 10.5 1.6e-07 31.7 0.2 10.5 6 3 9 15 15 15 6 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAN03229.1 - 3.2e-12 46.9 4.9 0.0016 19.0 0.1 7.5 7 1 2 9 9 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN03229.1 - 3.3e-12 46.7 5.5 3.7e-06 27.1 0.1 4.5 4 2 0 4 4 3 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 GAN03229.1 - 6.1e-10 38.9 4.5 1.9e-09 37.3 0.4 3.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain CLASP_N PF12348.8 GAN03229.1 - 1.2e-09 38.1 0.0 0.0022 17.6 0.0 5.7 5 2 2 7 7 7 3 CLASP N terminal MMS19_C PF12460.8 GAN03229.1 - 2.1e-07 30.4 0.3 0.00058 19.1 0.0 3.9 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal Tti2 PF10521.9 GAN03229.1 - 1.8e-06 27.7 0.3 0.11 12.0 0.0 4.3 2 2 1 4 4 4 2 Tti2 family Adaptin_N PF01602.20 GAN03229.1 - 1.1e-05 24.2 6.7 0.014 14.0 0.2 4.4 3 3 1 4 4 4 2 Adaptin N terminal region DUF3385 PF11865.8 GAN03229.1 - 1.9e-05 24.6 7.9 0.053 13.4 0.0 7.1 6 2 0 6 6 6 1 Domain of unknown function (DUF3385) CTD_bind PF04818.13 GAN03229.1 - 0.00093 20.0 0.2 35 5.3 0.0 4.8 4 0 0 4 4 3 0 RNA polymerase II-binding domain. Arm PF00514.23 GAN03229.1 - 0.0042 17.1 5.2 18 5.6 0.0 5.9 5 1 1 6 6 5 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 GAN03229.1 - 0.0065 16.2 4.0 5.4 6.7 0.0 4.5 5 1 0 6 6 5 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 GAN03229.1 - 0.013 15.7 0.3 3.8 7.7 0.0 4.8 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_V PF14668.6 GAN03229.1 - 0.13 12.5 0.6 7.6 6.9 0.0 4.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 SMK-1 PF04802.15 GAN03229.1 - 0.22 11.3 1.3 2.2 8.1 0.2 3.0 2 1 1 3 3 3 0 Component of IIS longevity pathway SMK-1 COX15-CtaA PF02628.15 GAN03231.1 - 7e-108 360.5 3.7 8.4e-108 360.3 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Filament PF00038.21 GAN03232.1 - 1e-06 28.6 393.6 0.001 18.7 14.0 17.6 2 1 13 15 15 15 10 Intermediate filament protein ADIP PF11559.8 GAN03232.1 - 0.0071 16.4 15.4 0.0071 16.4 15.4 23.4 3 2 23 26 26 26 7 Afadin- and alpha -actinin-Binding DUF3361 PF11841.8 GAN03233.1 - 4.4e-34 117.7 1.4 8.5e-34 116.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 GAN03233.1 - 1.2e-33 116.7 1.7 1.3e-32 113.3 0.3 2.8 3 1 0 3 3 3 1 ELMO/CED-12 family PH_12 PF16457.5 GAN03233.1 - 2.5e-32 112.2 0.5 1.7e-30 106.3 0.2 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain Frankia_peptide PF14407.6 GAN03234.1 - 0.038 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Motilin_assoc PF04643.12 GAN03234.1 - 0.059 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide zf_ZIC PF18366.1 GAN03234.1 - 0.19 11.9 0.2 0.45 10.7 0.2 1.5 1 0 0 1 1 1 0 Zic proteins zinc finger domain Diphthamide_syn PF01866.17 GAN03236.1 - 4e-118 394.3 0.0 8.7e-118 393.2 0.0 1.5 2 0 0 2 2 2 1 Putative diphthamide synthesis protein SUR7 PF06687.12 GAN03236.1 - 2.7e-09 37.0 7.4 7.2e-09 35.6 5.9 2.1 1 1 1 2 2 2 1 SUR7/PalI family EI24 PF07264.11 GAN03236.1 - 0.7 10.1 6.8 1.2 9.4 6.8 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DIL PF01843.19 GAN03237.1 - 9.8e-27 93.3 6.8 9.8e-27 93.3 6.8 2.5 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 GAN03237.1 - 5.3e-16 59.0 0.2 1.7e-15 57.3 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN03237.1 - 3.7e-15 56.1 0.7 2.1e-09 37.7 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN03237.1 - 1.4e-11 44.4 0.1 0.00018 21.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAN03237.1 - 6e-09 36.0 1.9 0.00018 21.8 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAN03237.1 - 3.9e-05 23.7 0.3 0.25 12.0 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat 7tm_3 PF00003.22 GAN03238.1 - 5.6e-37 127.7 28.9 9.2e-37 127.0 28.9 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 GAN03238.1 - 3e-34 118.7 0.7 4.7e-34 118.0 0.7 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 GAN03238.1 - 1.5e-14 54.4 0.5 2.5e-14 53.7 0.5 1.3 1 0 0 1 1 1 1 Periplasmic binding protein SDP_N PF12278.8 GAN03238.1 - 1.3 9.1 3.3 3.2 7.9 3.3 1.6 1 0 0 1 1 1 0 Sex determination protein N terminal WD40 PF00400.32 GAN03239.1 - 1.4e-13 51.1 1.4 0.00095 19.9 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Voldacs PF03517.13 GAN03239.1 - 0.046 13.8 10.3 0.73 10.0 0.4 3.4 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling ANAPC4_WD40 PF12894.7 GAN03239.1 - 0.086 13.2 0.0 18 5.7 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 GAN03239.1 - 1.1 8.5 16.2 1.1 8.5 4.0 2.3 2 0 0 2 2 2 0 BUD22 FAM176 PF14851.6 GAN03239.1 - 2.1 8.0 10.9 6.5 6.4 1.2 2.6 2 0 0 2 2 2 0 FAM176 family IMUP PF15761.5 GAN03239.1 - 3.1 8.5 5.3 15 6.3 1.6 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein RXT2_N PF08595.11 GAN03239.1 - 3.2 7.8 12.7 6.2 6.8 2.0 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 GAN03239.1 - 5 7.6 21.7 6.9 7.1 6.6 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GCIP PF13324.6 GAN03239.1 - 7.6 6.1 8.6 2.4 7.7 1.7 2.6 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting Clathrin PF00637.20 GAN03240.1 - 8.5e-19 67.8 14.9 4.5e-17 62.2 3.4 3.4 4 0 0 4 4 4 2 Region in Clathrin and VPS VPS11_C PF12451.8 GAN03240.1 - 6.4e-16 58.3 0.8 1.4e-15 57.2 0.8 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 GAN03240.1 - 4.9e-08 32.9 5.9 1.1e-07 31.8 5.9 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 GAN03240.1 - 0.0076 16.1 5.8 0.014 15.2 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN03240.1 - 0.093 12.7 5.8 0.17 11.9 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAN03240.1 - 0.28 11.5 6.5 0.54 10.6 6.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 GAN03240.1 - 0.45 10.8 4.9 0.96 9.8 4.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain EF-hand_7 PF13499.6 GAN03241.1 - 1.2e-17 64.1 7.7 5.3e-14 52.4 2.8 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAN03241.1 - 4e-16 57.3 7.2 3.6e-06 26.1 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAN03241.1 - 3e-14 51.6 6.1 0.00021 20.9 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 GAN03241.1 - 2.2e-11 42.7 2.3 1.9e-05 23.9 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAN03241.1 - 1.6e-06 27.9 10.2 9e-05 22.2 2.2 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 GAN03241.1 - 1.5e-05 24.9 4.7 0.13 12.2 0.2 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN03241.1 - 0.00014 22.1 6.9 0.078 13.3 0.2 3.5 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Haemagg_act PF05860.13 GAN03241.1 - 0.0044 16.9 0.7 4.3 7.2 0.0 3.3 1 1 1 2 2 2 2 haemagglutination activity domain Drf_GBD PF06371.13 GAN03241.1 - 0.14 11.7 2.2 0.18 11.4 0.2 2.2 2 1 0 2 2 2 0 Diaphanous GTPase-binding Domain Dockerin_1 PF00404.18 GAN03241.1 - 0.17 12.1 5.8 1.3 9.3 1.1 3.5 2 1 1 3 3 3 0 Dockerin type I domain Caleosin PF05042.13 GAN03241.1 - 1.1 9.2 7.0 17 5.3 1.0 3.4 2 2 2 4 4 4 0 Caleosin related protein AOX PF01786.17 GAN03242.1 - 1.6e-78 263.2 0.0 2.4e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase Peptidase_M50 PF02163.22 GAN03243.1 - 1.1e-14 54.3 0.0 2.9e-14 53.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M50 EB PF01683.18 GAN03243.1 - 0.012 15.9 0.2 0.03 14.6 0.2 1.7 1 0 0 1 1 1 0 EB module RAMP4 PF06624.12 GAN03243.1 - 0.12 12.5 0.7 0.21 11.7 0.7 1.3 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 cNMP_binding PF00027.29 GAN03244.1 - 9.7e-42 141.0 0.1 2.1e-21 75.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ER_lumen_recept PF00810.18 GAN03244.1 - 1.4e-34 120.1 0.9 2.4e-34 119.3 0.9 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor RIIa PF02197.17 GAN03244.1 - 2.5e-09 36.6 1.2 6.1e-09 35.4 1.2 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF2040 PF09745.9 GAN03245.1 - 1.9e-35 121.6 20.6 1.9e-35 121.6 20.6 4.2 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) SH3_1 PF00018.28 GAN03246.1 - 1.3e-11 43.9 0.0 2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN03246.1 - 7e-09 35.4 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN03246.1 - 5.1e-08 32.5 0.0 9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 GAN03246.1 - 0.14 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain NDUF_B7 PF05676.13 GAN03248.1 - 0.012 15.3 4.1 0.012 15.3 4.1 1.7 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 GAN03248.1 - 0.016 15.2 4.0 0.025 14.6 4.0 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 GAN03248.1 - 0.021 15.0 1.1 0.021 15.0 1.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 GAN03248.1 - 0.047 14.0 1.1 0.093 13.0 1.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Ndufs5 PF10200.9 GAN03248.1 - 0.061 13.6 3.5 0.1 12.9 3.5 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 GAN03248.1 - 0.1 12.9 4.9 0.15 12.5 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) START PF01852.19 GAN03249.1 - 3.1e-17 62.7 0.5 2.3e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 START domain Glyco_hydro_5_C PF18564.1 GAN03249.1 - 0.0024 18.3 0.7 0.011 16.3 0.0 2.5 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain KdgT PF03812.13 GAN03249.1 - 0.6 9.4 5.0 1 8.6 5.0 1.3 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease EII-Sor PF03609.14 GAN03250.1 - 0.32 10.4 6.6 0.57 9.5 5.7 1.9 1 1 0 1 1 1 0 PTS system sorbose-specific iic component Mago_nashi PF02792.14 GAN03251.1 - 1.9e-74 248.5 0.9 2.1e-74 248.4 0.9 1.0 1 0 0 1 1 1 1 Mago nashi protein HMG_box PF00505.19 GAN03252.1 - 1e-15 57.9 0.2 1e-15 57.9 0.2 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN03252.1 - 1.5e-11 44.7 0.2 3.9e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain 6PF2K PF01591.18 GAN03252.1 - 0.11 11.8 0.5 0.19 11.0 0.5 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CASP_C PF08172.12 GAN03252.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.1 3 0 0 3 3 3 0 CASP C terminal Lin-8 PF03353.15 GAN03252.1 - 3.4 7.1 18.5 0.19 11.3 10.8 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TSNAXIP1_N PF15739.5 GAN03252.1 - 9.3 6.7 10.7 4.2 7.8 2.4 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus RNA_pol_Rpc4 PF05132.14 GAN03253.1 - 9.5e-31 107.2 0.2 9.5e-31 107.2 0.2 3.1 3 0 0 3 3 3 1 RNA polymerase III RPC4 PIG-L PF02585.17 GAN03253.1 - 8.1e-28 97.7 0.0 1.5e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF4999 PF16390.5 GAN03253.1 - 0.055 13.7 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function ATP19 PF11022.8 GAN03253.1 - 0.61 10.5 2.4 0.6 10.5 0.2 2.1 2 0 0 2 2 2 0 ATP synthase subunit K F-box-like PF12937.7 GAN03254.1 - 8.9e-09 35.1 0.8 1.9e-08 34.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like UNC45-central PF11701.8 GAN03255.1 - 2e-35 122.0 10.1 6.1e-35 120.4 0.3 4.9 5 1 1 6 6 6 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 GAN03255.1 - 2.5e-05 24.6 12.1 0.11 12.9 0.1 6.3 3 2 4 7 7 7 3 HEAT repeats TPR_15 PF13429.6 GAN03255.1 - 0.0044 16.3 2.3 0.0044 16.3 2.3 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Arm_3 PF16186.5 GAN03255.1 - 0.0044 16.5 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Atypical Arm repeat DUF410 PF04190.13 GAN03255.1 - 0.0056 16.5 1.3 0.033 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF410) TPR_1 PF00515.28 GAN03255.1 - 0.078 12.8 0.3 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Herpes_UL51 PF04540.13 GAN03255.1 - 0.48 10.1 4.0 0.46 10.2 0.1 2.8 3 0 0 3 3 3 0 Herpesvirus UL51 protein UME PF08064.13 GAN03255.1 - 1.5 8.8 4.4 3.7 7.5 0.2 3.4 4 0 0 4 4 4 0 UME (NUC010) domain HEAT PF02985.22 GAN03255.1 - 9.7 6.8 10.2 16 6.1 0.1 5.7 6 0 0 6 6 6 0 HEAT repeat CK2S PF15011.6 GAN03256.1 - 8.5e-10 38.7 1.0 1.2e-09 38.2 1.0 1.3 1 0 0 1 1 1 1 Casein Kinase 2 substrate THP2 PF09432.10 GAN03256.1 - 0.021 14.9 0.2 0.46 10.5 0.0 2.4 2 0 0 2 2 2 0 Tho complex subunit THP2 ABC_tran_CTD PF16326.5 GAN03256.1 - 0.05 13.9 3.4 2.1 8.6 0.5 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DASH_Dam1 PF08653.10 GAN03256.1 - 0.05 13.4 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 HAUS-augmin3 PF14932.6 GAN03256.1 - 0.08 12.5 1.8 0.23 11.0 1.8 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2935 PF11155.8 GAN03256.1 - 0.11 12.8 0.8 0.29 11.5 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) SlyX PF04102.12 GAN03256.1 - 0.53 10.9 2.4 1.6 9.4 0.7 2.3 2 0 0 2 2 2 0 SlyX HLH PF00010.26 GAN03257.1 - 8.5e-14 51.3 1.6 8.5e-14 51.3 1.6 2.1 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain HAUS-augmin3 PF14932.6 GAN03257.1 - 0.99 8.9 13.0 0.46 10.0 0.9 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 NRBF2 PF08961.10 GAN03257.1 - 1.3 8.6 11.0 4.4 6.9 10.9 2.0 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF5345 PF17280.2 GAN03257.1 - 2.4 8.2 4.5 8.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) GEMIN8 PF15348.6 GAN03257.1 - 3.5 7.9 14.2 5.9 7.1 14.2 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 UPF0242 PF06785.11 GAN03257.1 - 4.3 7.4 18.1 0.45 10.6 10.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NAM-associated PF14303.6 GAN03257.1 - 7.9 7.2 16.5 0.17 12.6 8.6 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain bZIP_1 PF00170.21 GAN03258.1 - 3.1e-10 40.0 10.6 4.3e-10 39.5 9.3 2.0 1 1 0 1 1 1 1 bZIP transcription factor SUIM_assoc PF16619.5 GAN03258.1 - 0.025 14.6 5.1 0.025 14.6 5.1 5.2 4 2 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Cnn_1N PF07989.11 GAN03258.1 - 0.068 13.3 0.4 0.068 13.3 0.4 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 GAN03258.1 - 0.14 12.6 0.8 0.44 11.0 0.8 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) BMFP PF04380.13 GAN03258.1 - 0.28 11.7 5.2 0.81 10.2 5.2 1.8 1 0 0 1 1 1 0 Membrane fusogenic activity GalKase_gal_bdg PF10509.9 GAN03259.1 - 8.2e-22 76.5 0.1 1.7e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 GAN03259.1 - 4.6e-14 52.4 2.8 1.1e-13 51.1 2.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAN03259.1 - 7.2e-14 51.9 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4 PF04545.16 GAN03259.1 - 0.075 12.6 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Aldedh PF00171.22 GAN03260.1 - 7.4e-132 440.1 0.0 9.5e-132 439.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RPEL PF02755.15 GAN03262.1 - 6.5e-29 98.8 16.7 3.9e-09 35.9 0.6 4.9 4 1 1 5 5 5 4 RPEL repeat DnaI_N PF07319.11 GAN03262.1 - 0.0007 20.2 1.7 0.12 13.0 0.3 2.4 1 1 1 2 2 2 2 Primosomal protein DnaI N-terminus TPT PF03151.16 GAN03263.1 - 4.9e-19 68.8 17.3 5.7e-19 68.6 17.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 GAN03263.1 - 0.044 13.0 21.6 2 7.5 21.6 2.2 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Sec61_beta PF03911.16 GAN03263.1 - 0.63 10.1 0.1 0.63 10.1 0.1 2.8 3 0 0 3 3 3 0 Sec61beta family Kelch_6 PF13964.6 GAN03264.1 - 0.00081 19.6 0.1 5.7 7.4 0.0 3.6 3 0 0 3 3 3 2 Kelch motif RAG2 PF03089.14 GAN03264.1 - 0.0028 16.7 0.1 0.079 11.9 0.0 2.4 3 0 0 3 3 3 1 Recombination activating protein 2 Kelch_5 PF13854.6 GAN03264.1 - 0.0047 16.9 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 GAN03264.1 - 0.062 12.9 1.4 10 5.8 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 GAN03265.1 - 1.3e-06 28.4 0.7 3.6 8.0 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 GAN03265.1 - 0.00019 21.3 0.1 1.5 8.9 0.0 3.8 3 0 0 3 3 3 2 Kelch motif DUF4131 PF13567.6 GAN03265.1 - 0.046 13.4 1.3 0.11 12.1 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 GAN03265.1 - 0.073 11.8 3.6 0.22 10.2 0.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) VSP PF03302.13 GAN03265.1 - 0.087 11.7 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Kelch_1 PF01344.25 GAN03265.1 - 0.11 12.1 4.9 29 4.4 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Staphostatin_B PF09023.10 GAN03266.1 - 0.33 11.0 4.3 0.22 11.6 0.5 2.5 3 0 0 3 3 3 0 Staphostatin B BMFP PF04380.13 GAN03266.1 - 0.57 10.7 9.8 1 9.9 2.2 3.0 3 0 0 3 3 3 0 Membrane fusogenic activity M PF02370.16 GAN03266.1 - 1.1 10.1 6.4 0.61 10.8 1.7 3.2 2 0 0 2 2 2 0 M protein repeat HA2 PF04408.23 GAN03267.1 - 1.8e-15 57.1 0.0 6.3e-15 55.4 0.0 2.1 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAN03267.1 - 4.1e-14 52.9 0.0 1.2e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAN03267.1 - 1.9e-12 47.4 0.0 5.8e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAN03267.1 - 6.8e-06 26.0 0.2 1.7e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Rad17 PF03215.15 GAN03267.1 - 2.6e-05 24.2 0.1 5.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GAN03267.1 - 3.3e-05 24.2 2.0 7.1e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAN03267.1 - 0.0062 17.1 1.9 0.64 10.5 0.0 3.0 2 1 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 GAN03267.1 - 0.0097 16.2 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain CobT PF06213.12 GAN03267.1 - 0.012 15.0 4.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT T2SSE PF00437.20 GAN03267.1 - 0.018 14.1 0.1 0.061 12.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein PAGK PF15284.6 GAN03267.1 - 0.033 14.1 0.1 0.092 12.7 0.1 1.7 1 0 0 1 1 1 0 Phage-encoded virulence factor FtsK_SpoIIIE PF01580.18 GAN03267.1 - 0.12 11.7 0.3 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 GAN03267.1 - 0.16 12.4 0.0 0.63 10.5 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asp PF00026.23 GAN03268.1 - 1.9e-26 93.2 1.7 5.4e-26 91.8 1.7 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease MGC-24 PF05283.11 GAN03269.1 - 4.7 7.7 17.5 2.2 8.8 6.9 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ECH_1 PF00378.20 GAN03270.1 - 2.2e-41 141.8 0.0 2.9e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN03270.1 - 7.5e-17 61.8 0.0 8.5e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribosomal_L15e PF00827.17 GAN03271.1 - 3.1e-69 232.6 8.6 9.3e-62 208.1 3.0 2.0 1 1 1 2 2 2 2 Ribosomal L15 F-box-like PF12937.7 GAN03272.1 - 1.3e-07 31.4 2.5 1.6e-07 31.1 0.0 2.4 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 GAN03272.1 - 4.4e-06 27.0 11.3 0.15 12.5 0.1 5.8 3 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAN03272.1 - 0.00022 21.0 15.4 2.9 8.2 0.7 6.8 7 0 0 7 7 7 3 Leucine Rich repeat HEAT_EZ PF13513.6 GAN03273.1 - 2e-14 53.7 7.8 1.2e-10 41.6 0.0 5.8 6 1 1 7 7 6 3 HEAT-like repeat HEAT PF02985.22 GAN03273.1 - 1.9e-12 46.3 8.8 0.0028 17.8 0.0 8.9 10 0 0 10 10 9 2 HEAT repeat HEAT_2 PF13646.6 GAN03273.1 - 2.4e-10 40.6 0.0 0.16 12.3 0.0 5.7 4 2 1 5 5 5 2 HEAT repeats IBN_N PF03810.19 GAN03273.1 - 2.2e-08 33.9 0.1 3.1e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 GAN03273.1 - 7.1e-07 29.7 0.1 25 5.5 0.0 5.4 3 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 GAN03273.1 - 3.3e-05 23.8 0.8 0.15 12.1 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 GAN03273.1 - 0.00066 18.4 1.5 0.66 8.5 0.2 3.4 2 2 1 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.8 GAN03273.1 - 0.0096 15.1 9.2 2.3 7.2 0.0 4.8 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal RXT2_N PF08595.11 GAN03273.1 - 0.093 12.8 1.0 0.26 11.3 1.0 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Proteasom_PSMB PF10508.9 GAN03273.1 - 0.096 11.2 0.0 0.38 9.2 0.0 1.9 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit TAF6_C PF07571.13 GAN03273.1 - 0.11 12.8 0.1 1.9 8.9 0.0 2.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 GAN03273.1 - 0.12 11.9 0.1 10 5.6 0.1 2.9 2 1 1 3 3 3 0 CLASP N terminal FAM176 PF14851.6 GAN03273.1 - 0.71 9.5 3.5 1.3 8.7 3.5 1.3 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 GAN03273.1 - 0.92 9.9 7.6 2.8 8.4 7.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HEAT_EZ PF13513.6 GAN03274.1 - 4e-06 27.2 0.3 0.0018 18.7 0.0 3.2 3 1 1 4 4 4 1 HEAT-like repeat Arm PF00514.23 GAN03274.1 - 0.00049 20.0 0.1 0.39 10.8 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat PAP_central PF04928.17 GAN03274.1 - 0.079 11.9 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain Exostosin PF03016.15 GAN03275.1 - 2.4e-38 132.1 0.7 3e-38 131.7 0.7 1.0 1 0 0 1 1 1 1 Exostosin family Glyco_transf_10 PF00852.19 GAN03275.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Ribosomal_S21 PF01165.20 GAN03276.1 - 7.8e-13 47.9 2.6 7.8e-13 47.9 2.6 1.5 2 0 0 2 2 2 1 Ribosomal protein S21 Exo_endo_phos PF03372.23 GAN03277.1 - 3.4e-08 33.3 0.0 1.5e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 GAN03278.1 - 6.5e-42 142.9 0.1 2.1e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 GAN03278.1 - 1.3e-18 67.4 0.3 3.4e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 PH domain PX PF00787.24 GAN03278.1 - 2.2e-10 40.5 0.0 6.5e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 GAN03278.1 - 3.7e-10 40.2 0.2 1.8e-09 38.0 0.2 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAN03278.1 - 0.00014 22.1 0.1 0.0011 19.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain TMEM192 PF14802.6 GAN03278.1 - 0.14 11.3 0.6 0.25 10.4 0.6 1.3 1 0 0 1 1 1 0 TMEM192 family Roughex PF06020.11 GAN03278.1 - 0.73 8.9 7.2 0.19 10.8 3.1 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Mg_trans_NIPA PF05653.14 GAN03279.1 - 2.5e-19 69.5 15.4 8.4e-10 38.2 2.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAN03279.1 - 0.0034 17.6 3.8 0.0034 17.6 3.8 3.4 3 1 0 3 3 3 2 EamA-like transporter family LapA_dom PF06305.11 GAN03279.1 - 0.21 11.4 10.8 3 7.7 0.2 4.1 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Cyclin_N PF00134.23 GAN03280.1 - 3.1e-13 49.6 1.5 3.6e-13 49.4 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Chitin_bind_1 PF00187.19 GAN03281.1 - 0.068 13.7 0.8 0.068 13.7 0.8 2.2 2 0 0 2 2 2 0 Chitin recognition protein Acyltransferase PF01553.21 GAN03282.1 - 8.4e-36 122.6 0.0 1.1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 GAN03282.1 - 0.043 13.0 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Pkinase PF00069.25 GAN03283.1 - 2.6e-57 194.2 0.0 3.3e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03283.1 - 4.4e-31 108.1 0.0 6.2e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN03283.1 - 6.7e-06 25.6 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN03283.1 - 1.2e-05 24.3 0.1 2.7e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAN03283.1 - 0.016 14.5 0.4 0.029 13.7 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN03283.1 - 0.1 12.5 1.4 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Na_Ca_ex PF01699.24 GAN03284.1 - 5.6e-43 146.5 42.4 1.2e-22 80.5 14.8 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FA_desaturase PF00487.24 GAN03285.1 - 0.03 14.2 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase SPX PF03105.19 GAN03285.1 - 4.8 7.0 8.2 5.9 6.7 8.2 1.1 1 0 0 1 1 1 0 SPX domain bZIP_1 PF00170.21 GAN03286.1 - 2.9e-12 46.5 8.1 5.4e-12 45.6 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN03286.1 - 1e-08 35.1 7.3 2.5e-08 33.9 7.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper ZapB PF06005.12 GAN03286.1 - 0.0041 17.5 0.0 0.015 15.7 0.0 2.0 1 1 1 2 2 2 1 Cell division protein ZapB bZIP_Maf PF03131.17 GAN03286.1 - 0.0052 17.3 8.6 0.008 16.7 7.3 2.0 1 1 0 1 1 1 1 bZIP Maf transcription factor HAP1_N PF04849.13 GAN03286.1 - 0.006 15.8 5.5 0.011 15.0 5.5 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4171 PF13775.6 GAN03286.1 - 0.017 15.6 4.2 0.038 14.4 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) LPD29 PF18847.1 GAN03286.1 - 0.095 13.6 1.7 0.13 13.2 0.1 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 29 Macoilin PF09726.9 GAN03286.1 - 0.096 11.2 8.9 0.13 10.8 8.9 1.2 1 0 0 1 1 1 0 Macoilin family HMG_box PF00505.19 GAN03288.1 - 5.9e-18 65.1 3.1 1.4e-17 63.8 3.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN03288.1 - 1.3e-06 28.9 1.6 2.5e-06 28.0 1.6 1.5 1 0 0 1 1 1 1 HMG-box domain Retrotrans_gag PF03732.17 GAN03289.1 - 0.11 12.8 1.2 0.18 12.1 1.1 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein F-box-like PF12937.7 GAN03290.1 - 0.00048 20.0 0.1 0.002 18.0 0.1 2.2 1 0 0 1 1 1 1 F-box-like SPW PF03779.14 GAN03290.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SPW repeat RPAP3_C PF13877.6 GAN03290.1 - 0.13 12.8 0.6 17 6.0 0.1 2.7 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 F-box-like_2 PF13013.6 GAN03290.1 - 1 9.4 4.4 2 8.4 0.2 3.4 4 0 0 4 4 4 0 F-box-like domain PAS_3 PF08447.12 GAN03291.1 - 7.1e-16 58.3 0.0 1.7e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold GATA PF00320.27 GAN03291.1 - 5e-14 51.6 8.1 8.4e-14 50.9 8.1 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 GAN03291.1 - 7e-10 38.9 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAN03291.1 - 2e-07 31.2 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAN03291.1 - 1.4e-06 28.5 0.0 3.7e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 GAN03291.1 - 2.2e-06 27.7 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 PAS domain WRKY PF03106.15 GAN03292.1 - 2.7e-09 37.1 2.5 5.6e-09 36.1 2.5 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain TisB_toxin PF13939.6 GAN03293.1 - 0.15 11.9 0.4 0.3 10.9 0.4 1.5 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system Svf1_C PF17187.4 GAN03294.1 - 1.6e-52 177.7 0.8 2.4e-52 177.1 0.8 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 GAN03294.1 - 5.7e-38 130.6 1.5 9.5e-38 129.8 0.2 1.9 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain PHD PF00628.29 GAN03295.1 - 8.6e-09 35.2 16.2 1.2e-08 34.7 15.2 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 GAN03295.1 - 0.0071 15.9 8.9 0.014 15.0 8.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 GAN03295.1 - 0.1 12.6 7.6 0.33 11.0 6.4 2.3 2 0 0 2 2 2 0 CW-type Zinc Finger Coilin_N PF15862.5 GAN03295.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.6 3 1 0 3 3 3 0 Coilin N-terminus DUF4530 PF15039.6 GAN03295.1 - 3.2 7.9 8.1 26 5.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4530) CENP-B_dimeris PF09026.10 GAN03295.1 - 9.6 6.7 9.0 4.9 7.6 0.9 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF3138 PF11336.8 GAN03296.1 - 0.024 13.2 0.0 0.029 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1258 PF06869.12 GAN03297.1 - 0.0006 19.4 0.0 0.0008 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) HEAT PF02985.22 GAN03298.1 - 2.8e-15 55.1 5.3 0.026 14.8 0.0 7.5 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 GAN03298.1 - 1.2e-07 32.1 1.3 0.00065 20.0 0.0 5.0 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 GAN03298.1 - 1.2e-05 25.4 2.2 0.0063 16.6 0.0 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAN03298.1 - 0.00053 20.4 2.0 3.4 8.3 0.1 4.5 4 0 0 4 4 4 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAN03298.1 - 0.03 14.9 3.5 50 4.6 0.1 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF2890 PF11081.8 GAN03298.1 - 1.1 9.3 9.2 0.19 11.8 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Not3 PF04065.15 GAN03299.1 - 2.7e-92 308.4 27.0 4.9e-92 307.5 27.0 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GAN03299.1 - 1.4e-45 154.6 12.8 4.6e-45 152.9 12.8 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 GAN03299.1 - 0.6 10.5 9.2 0.21 11.9 5.3 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DUF4407 PF14362.6 GAN03299.1 - 1 8.7 9.2 2.2 7.6 9.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HR1 PF02185.16 GAN03299.1 - 5.2 7.3 10.5 0.26 11.4 3.6 2.3 2 0 0 2 2 2 0 Hr1 repeat VTC PF09359.10 GAN03300.1 - 1.5e-85 287.0 0.4 2.4e-85 286.3 0.4 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 GAN03300.1 - 1.9e-15 57.7 11.4 4.3e-09 36.8 0.1 4.0 2 1 2 4 4 4 3 SPX domain Sda PF08970.10 GAN03300.1 - 0.042 13.6 0.1 0.61 9.9 0.4 2.5 2 0 0 2 2 2 0 Sporulation inhibitor A VTC PF09359.10 GAN03301.1 - 8.2e-37 127.1 0.1 8.2e-37 127.1 0.1 1.7 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAN03301.1 - 3.7e-14 52.9 5.6 5.1e-14 52.5 4.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HTH_psq PF05225.16 GAN03302.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Acyl-CoA_dh_1 PF00441.24 GAN03303.1 - 2.2e-32 112.3 0.7 3.3e-32 111.8 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAN03303.1 - 1.4e-20 73.2 0.0 3.8e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAN03303.1 - 1.2e-14 54.9 0.0 2.7e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAN03303.1 - 3.2e-13 50.1 0.7 5.6e-13 49.3 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAN03303.1 - 0.00023 20.9 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal START PF01852.19 GAN03304.1 - 5.6e-24 84.7 0.1 5.9e-13 48.7 0.0 2.6 2 1 0 2 2 2 2 START domain Glyco_hydro_5_C PF18564.1 GAN03304.1 - 0.0018 18.8 0.1 0.0084 16.6 0.1 2.2 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Pkinase PF00069.25 GAN03305.1 - 5.4e-58 196.4 0.1 3.5e-57 193.8 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03305.1 - 1.6e-33 116.1 0.0 1.4e-32 113.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN03305.1 - 9e-05 22.5 1.9 0.043 13.7 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN03305.1 - 0.0033 16.4 0.2 0.0033 16.4 0.2 2.9 4 0 0 4 4 4 1 Haspin like kinase domain Kinase-like PF14531.6 GAN03305.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAN03305.1 - 0.31 9.8 0.0 0.31 9.8 0.0 3.1 3 0 0 3 3 3 0 Fungal protein kinase Gcn1_N PF12074.8 GAN03306.1 - 1.2e-95 320.9 7.0 1.2e-95 320.9 7.0 5.1 6 0 0 6 6 6 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 GAN03306.1 - 1e-39 131.1 31.0 0.00012 22.0 0.0 22.1 25 1 1 26 26 22 7 HEAT repeat HEAT_EZ PF13513.6 GAN03306.1 - 3.4e-31 107.2 32.7 0.012 16.1 0.1 19.1 16 3 2 19 19 18 6 HEAT-like repeat HEAT_2 PF13646.6 GAN03306.1 - 1.4e-28 99.1 34.0 0.001 19.4 0.2 16.4 12 2 7 19 19 18 8 HEAT repeats Cnd1 PF12717.7 GAN03306.1 - 1e-16 61.4 7.2 0.0034 17.4 0.2 10.4 7 3 2 11 11 11 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAN03306.1 - 3.6e-11 43.5 0.1 0.56 10.8 0.0 9.0 7 2 2 9 9 9 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAN03306.1 - 2.1e-10 40.6 0.0 0.0033 17.0 0.0 6.5 6 1 1 7 7 7 2 CLASP N terminal Adaptin_N PF01602.20 GAN03306.1 - 4e-10 38.9 11.3 0.0037 15.9 0.2 8.8 7 2 2 10 10 10 4 Adaptin N terminal region MMS19_C PF12460.8 GAN03306.1 - 1.6e-08 34.1 3.3 0.5 9.4 0.0 6.6 5 2 0 5 5 5 3 RNAPII transcription regulator C-terminal ParcG PF10274.9 GAN03306.1 - 1.1e-07 32.2 1.3 0.29 11.2 0.0 5.4 4 0 0 4 4 4 2 Parkin co-regulated protein DUF3385 PF11865.8 GAN03306.1 - 0.00055 19.9 1.2 23 4.8 0.0 7.0 8 1 0 8 8 8 0 Domain of unknown function (DUF3385) RasGEF_N_2 PF14663.6 GAN03306.1 - 0.0068 16.8 0.2 1.2 9.6 0.0 4.5 4 0 0 4 4 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 GAN03306.1 - 0.012 15.7 4.2 22 5.2 0.1 7.8 8 1 1 9 9 8 0 Armadillo/beta-catenin-like repeat EI24 PF07264.11 GAN03306.1 - 0.032 14.5 0.0 8.8 6.5 0.0 3.4 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) Sec7_N PF12783.7 GAN03306.1 - 0.075 12.9 0.5 2.1 8.2 0.0 3.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ALF PF03752.13 GAN03306.1 - 0.075 13.0 4.8 19 5.4 0.0 5.3 6 0 0 6 6 4 0 Short repeats of unknown function DRIM PF07539.12 GAN03306.1 - 0.11 10.8 7.5 0.92 7.7 0.1 5.3 8 0 0 8 8 8 0 Down-regulated in metastasis RIX1 PF08167.12 GAN03306.1 - 0.31 10.8 8.7 0.19 11.5 0.1 4.9 6 0 0 6 6 4 0 rRNA processing/ribosome biogenesis NUC173 PF08161.12 GAN03306.1 - 0.82 9.3 3.9 42 3.7 0.1 5.2 5 1 1 6 6 6 0 NUC173 domain ADSL_C PF10397.9 GAN03306.1 - 1.4 9.5 7.3 12 6.5 0.0 5.1 5 0 0 5 5 4 0 Adenylosuccinate lyase C-terminus MIT PF04212.18 GAN03307.1 - 3.8e-06 26.9 0.0 7.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Glyco_hydro_4C PF11975.8 GAN03307.1 - 0.00018 21.7 6.2 0.0004 20.5 5.8 1.6 1 1 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain Neur_chan_memb PF02932.16 GAN03307.1 - 0.14 12.2 11.3 0.46 10.5 8.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 GAN03307.1 - 1.4 8.9 19.9 0.25 11.3 13.3 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Mob1_phocein PF03637.17 GAN03308.1 - 3e-66 222.6 0.6 4e-66 222.2 0.6 1.1 1 0 0 1 1 1 1 Mob1/phocein family DPBB_1 PF03330.18 GAN03309.1 - 1.6e-11 44.3 0.1 3.4e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase DUF507 PF04368.13 GAN03309.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) zf-C2H2_4 PF13894.6 GAN03311.1 - 1.1e-13 50.8 79.9 0.021 15.6 1.2 10.8 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAN03311.1 - 1.2e-05 25.6 43.9 0.0075 16.6 2.6 8.4 4 2 4 9 9 9 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAN03311.1 - 3.4e-05 24.1 51.1 0.024 15.0 0.4 9.5 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN03311.1 - 0.00071 19.8 56.2 0.54 10.6 0.1 9.9 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAN03311.1 - 0.033 14.7 1.5 0.033 14.7 1.5 11.2 11 1 0 11 11 11 0 Zinc finger, C2H2 type DZR PF12773.7 GAN03311.1 - 0.11 12.5 30.9 7.5 6.7 3.3 6.1 4 2 0 4 4 4 0 Double zinc ribbon CpXC PF14353.6 GAN03311.1 - 0.24 11.5 0.1 0.24 11.5 0.1 4.9 4 1 1 5 5 5 0 CpXC protein zf_C2H2_ZHX PF18387.1 GAN03311.1 - 1.3 8.7 41.3 3.5 7.3 0.0 9.5 10 0 0 10 10 10 0 Zinc-fingers and homeoboxes C2H2 finger domain Rtf2 PF04641.12 GAN03311.1 - 1.3 8.3 4.5 0.67 9.3 0.0 2.7 3 0 0 3 3 3 0 Rtf2 RING-finger zinc_ribbon_15 PF17032.5 GAN03311.1 - 1.6 9.6 33.5 15 6.4 9.4 6.5 1 1 6 7 7 7 0 zinc-ribbon family PHD_Oberon PF07227.11 GAN03311.1 - 2 8.3 23.4 13 5.7 0.0 7.2 4 3 3 8 8 8 0 PHD - plant homeodomain finger protein zf-C2H2_3rep PF18868.1 GAN03311.1 - 9.8 6.9 21.2 0.13 12.9 2.9 5.7 5 3 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats CSTF2_hinge PF14327.6 GAN03312.1 - 4.9e-27 94.2 5.2 4.9e-27 94.2 5.2 2.6 4 0 0 4 4 4 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 GAN03312.1 - 1.9e-21 75.6 0.1 6.6e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 GAN03312.1 - 3.2e-10 39.4 3.9 3.2e-10 39.4 3.9 2.8 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 GAN03312.1 - 0.0083 16.2 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif MgtE_N PF03448.17 GAN03312.1 - 0.18 12.4 2.9 1.5 9.4 0.1 3.0 4 0 0 4 4 4 0 MgtE intracellular N domain SARAF PF06682.12 GAN03312.1 - 5.2 6.6 7.2 9.6 5.8 7.2 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TMEM208_SND2 PF05620.11 GAN03313.1 - 1.2e-58 197.6 1.6 1.4e-58 197.4 1.6 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Lgl_C PF08596.10 GAN03314.1 - 2.2e-13 49.7 0.1 5.5e-10 38.5 0.0 3.3 3 0 0 3 3 3 2 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 GAN03314.1 - 2.4e-07 30.9 0.1 0.25 11.7 0.0 5.4 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN03314.1 - 1.2e-06 29.1 9.7 0.0019 19.0 0.2 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat Synaptobrevin PF00957.21 GAN03314.1 - 0.0045 16.7 0.5 0.014 15.1 0.5 1.8 1 0 0 1 1 1 1 Synaptobrevin PQQ_3 PF13570.6 GAN03314.1 - 0.029 14.9 1.5 1.6 9.3 0.1 3.2 3 0 0 3 3 3 0 PQQ-like domain DUF2442 PF10387.9 GAN03314.1 - 0.11 12.9 0.1 37 4.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2442) bZIP_2 PF07716.15 GAN03315.1 - 1.7e-12 47.2 3.9 1.7e-12 47.2 3.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN03315.1 - 2.1e-10 40.5 4.2 2.1e-10 40.5 4.2 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAN03315.1 - 0.00029 21.3 3.6 0.00035 21.1 2.7 1.5 1 1 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 GAN03315.1 - 0.0031 17.2 0.9 0.0031 17.2 0.9 1.7 1 1 1 2 2 2 1 Septum formation initiator ADIP PF11559.8 GAN03315.1 - 0.02 15.0 2.7 0.02 15.0 2.7 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 GAN03315.1 - 0.021 14.4 5.7 0.029 14.0 5.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 GAN03315.1 - 0.025 13.9 4.9 0.03 13.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 GAN03315.1 - 0.037 13.3 6.7 0.078 12.2 6.7 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Striatin PF08232.12 GAN03315.1 - 0.13 12.8 0.7 0.13 12.8 0.7 2.0 1 1 1 2 2 2 0 Striatin family Hemagglutinin PF00509.18 GAN03315.1 - 0.17 10.2 0.6 0.22 9.9 0.6 1.1 1 0 0 1 1 1 0 Haemagglutinin ABC_tran_CTD PF16326.5 GAN03315.1 - 0.18 12.1 5.2 12 6.2 0.5 3.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain HalX PF08663.10 GAN03315.1 - 0.22 11.9 3.4 0.72 10.2 3.4 2.0 1 1 0 1 1 1 0 HalX domain Pox_A_type_inc PF04508.12 GAN03315.1 - 0.23 11.4 1.5 23 5.0 0.1 3.1 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat ZapB PF06005.12 GAN03315.1 - 0.46 11.0 10.0 0.11 13.0 4.1 2.1 1 1 1 2 2 2 0 Cell division protein ZapB CLZ PF16526.5 GAN03315.1 - 0.52 10.7 7.0 0.16 12.4 4.2 1.7 2 0 0 2 2 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 GAN03315.1 - 0.52 9.1 6.6 0.64 8.8 6.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup54 PF13874.6 GAN03315.1 - 1.4 9.0 8.7 1.8 8.7 8.7 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4140 PF13600.6 GAN03315.1 - 2.3 8.7 10.2 0.99 9.9 3.7 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Methyltransf_25 PF13649.6 GAN03316.1 - 3.6e-16 59.6 0.0 9.6e-16 58.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN03316.1 - 5.8e-12 45.8 0.0 8.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN03316.1 - 7e-12 45.8 0.0 1.8e-11 44.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN03316.1 - 9.9e-11 41.7 0.0 8e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN03316.1 - 6.1e-08 33.3 0.0 1.2e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN03316.1 - 1.4e-05 24.5 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN03316.1 - 6.9e-05 22.4 0.0 0.00025 20.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 GAN03316.1 - 0.00095 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 GAN03316.1 - 0.004 15.8 0.0 0.031 12.9 0.0 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 GAN03316.1 - 0.0068 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 GAN03316.1 - 0.0071 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 GAN03316.1 - 0.039 13.5 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 GAN03316.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 GAN03316.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 GAN03316.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Abhydrolase_1 PF00561.20 GAN03317.1 - 3.8e-10 39.9 0.3 3.5e-07 30.1 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN03317.1 - 3.1e-08 34.5 0.0 5.9e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN03317.1 - 6.5e-07 28.9 0.0 7.7e-05 22.1 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Lipase PF00151.19 GAN03317.1 - 0.00032 20.1 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipase Thioesterase PF00975.20 GAN03317.1 - 0.0025 18.0 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 GAN03317.1 - 0.0028 17.3 0.0 0.013 15.1 0.0 2.0 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 GAN03317.1 - 0.0038 16.9 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 GAN03317.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 GAN03317.1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF1057 PF06342.12 GAN03317.1 - 0.083 11.9 0.0 0.18 10.8 0.0 1.5 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 GAN03317.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAN03317.1 - 0.15 11.7 0.1 0.48 10.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_2 PF02230.16 GAN03317.1 - 0.16 11.8 0.0 1.8 8.3 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Vps5 PF09325.10 GAN03318.1 - 1.2e-09 38.1 6.1 2.2e-09 37.3 5.3 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 GAN03318.1 - 5e-05 23.3 0.1 0.00012 22.0 0.1 1.8 1 0 0 1 1 1 1 PX domain DMRL_synthase PF00885.19 GAN03319.1 - 1.4e-50 170.8 0.1 2e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TMPIT PF07851.13 GAN03321.1 - 0.63 9.2 4.0 0.92 8.7 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein RVT_1 PF00078.27 GAN03322.1 - 5.6e-08 32.6 0.2 1.1e-06 28.4 0.2 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.27 GAN03325.1 - 8.8e-28 96.1 5.7 2.5e-12 46.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN03325.1 - 0.01 15.0 0.5 0.052 12.7 0.1 2.2 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Bacteriocin_IIc PF10439.9 GAN03325.1 - 1.1 9.4 8.8 7.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Sec10 PF07393.11 GAN03326.1 - 6.6e-100 335.6 4.3 2.1e-88 297.6 1.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.7 GAN03326.1 - 2.3e-08 33.8 0.1 5e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03326.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Sporozoite_P67 PF05642.11 GAN03326.1 - 0.25 9.4 2.3 0.37 8.8 2.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cyclin PF08613.11 GAN03327.1 - 3.6e-32 112.0 6.0 1.1e-26 94.1 2.7 2.4 1 1 1 2 2 2 2 Cyclin Cyclin_N PF00134.23 GAN03327.1 - 0.012 15.3 0.2 0.012 15.3 0.2 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF1635 PF07795.11 GAN03327.1 - 0.25 11.2 3.2 0.16 11.8 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Microvir_J PF04726.13 GAN03331.1 - 0.63 10.1 4.0 1.1 9.3 4.0 1.3 1 0 0 1 1 1 0 Microvirus J protein Ribosomal_S13 PF00416.22 GAN03332.1 - 1.9e-52 177.0 2.6 2.6e-52 176.6 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAN03332.1 - 0.025 13.4 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 GAN03332.1 - 0.086 11.9 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Pkinase PF00069.25 GAN03334.1 - 9.6e-75 251.3 0.0 1.4e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03334.1 - 1e-33 116.7 0.0 1.6e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN03334.1 - 4.5e-06 26.2 0.0 5e-05 22.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAN03334.1 - 0.0066 15.4 0.1 0.17 10.8 0.1 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAN03334.1 - 0.0079 15.0 0.1 0.0079 15.0 0.1 2.3 3 0 0 3 3 3 1 Fungal protein kinase SOG2 PF10428.9 GAN03334.1 - 3.5 6.7 17.1 3.1 6.9 8.4 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein Aconitase PF00330.20 GAN03335.1 - 6.4e-153 510.1 0.0 9.2e-153 509.5 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAN03335.1 - 5.3e-40 136.8 0.1 1e-39 135.8 0.1 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain BET PF17035.5 GAN03336.1 - 7.4e-07 29.2 2.2 2.2e-06 27.7 2.2 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SR-25 PF10500.9 GAN03336.1 - 0.00026 20.7 29.6 0.00076 19.2 6.0 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF3246 PF11596.8 GAN03336.1 - 0.75 9.2 7.7 1.3 8.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Myc_N PF01056.18 GAN03337.1 - 0.00016 21.7 0.6 0.00019 21.5 0.6 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Astro_capsid_p PF12226.8 GAN03337.1 - 0.043 13.0 1.1 0.048 12.8 1.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nucleo_P87 PF07267.11 GAN03337.1 - 0.048 12.5 2.0 0.051 12.4 2.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3672 PF12421.8 GAN03337.1 - 0.084 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Fibronectin type III protein DUF3432 PF11914.8 GAN03337.1 - 0.14 12.4 13.3 0.37 11.1 13.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) FAM176 PF14851.6 GAN03337.1 - 2.6 7.7 6.9 3.9 7.1 6.9 1.3 1 0 0 1 1 1 0 FAM176 family Radial_spoke PF04712.12 GAN03337.1 - 3.3 6.5 8.6 4.5 6.1 8.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.12 GAN03337.1 - 6.5 6.0 13.1 8.8 5.5 13.1 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GAN03337.1 - 9.4 4.4 8.0 12 4.1 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 GAN03338.1 - 0.0041 17.4 7.3 0.0081 16.4 7.3 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 GAN03338.1 - 0.018 14.2 4.7 0.015 14.5 2.6 1.8 2 0 0 2 2 2 0 Turkey astrovirus capsid protein NOA36 PF06524.12 GAN03338.1 - 0.33 10.2 9.7 0.46 9.8 9.7 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GAN03338.1 - 0.84 9.3 5.9 1.9 8.1 5.9 1.6 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 GAN03338.1 - 1.1 9.3 5.2 1.8 8.6 5.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.6 GAN03338.1 - 1.7 8.9 9.3 3.6 7.9 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 GAN03338.1 - 6.4 4.9 8.4 8.4 4.5 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-met2 PF12907.7 GAN03339.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding PPP4R2 PF09184.11 GAN03340.1 - 1.5 8.4 17.6 2.4 7.7 17.6 1.3 1 0 0 1 1 1 0 PPP4R2 bZIP_1 PF00170.21 GAN03341.1 - 1.9e-07 31.1 16.3 1.6e-06 28.1 16.3 2.2 1 1 0 1 1 1 1 bZIP transcription factor NYD-SP28_assoc PF14775.6 GAN03341.1 - 0.017 15.2 2.2 0.039 14.0 2.2 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain HAUS6_N PF14661.6 GAN03341.1 - 0.61 9.6 11.3 0.63 9.6 10.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Aminotran_1_2 PF00155.21 GAN03342.1 - 7e-21 74.8 0.0 8.4e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAN03342.1 - 4e-05 22.6 0.0 0.00012 21.0 0.0 1.6 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase Ras PF00071.22 GAN03345.1 - 1.6e-23 83.1 0.3 2.2e-23 82.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN03345.1 - 6.3e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN03345.1 - 0.00054 19.5 0.1 0.00074 19.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GATA PF00320.27 GAN03346.1 - 1.4e-14 53.4 6.1 1.4e-14 53.4 6.1 1.9 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.7 GAN03346.1 - 1.1 9.3 3.8 15 5.7 3.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon SprA-related PF12118.8 GAN03346.1 - 6.1 5.9 10.8 14 4.7 6.8 2.3 2 0 0 2 2 2 0 SprA-related family TFIIA PF03153.13 GAN03346.1 - 9.5 6.1 18.3 71 3.2 18.4 2.1 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rep_fac_C PF08542.11 GAN03347.1 - 2.1e-21 76.1 0.1 7e-21 74.4 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 GAN03347.1 - 3.3e-18 66.4 0.0 6.8e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAN03347.1 - 5.1e-15 55.6 0.1 1.4e-11 44.4 0.1 2.6 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 GAN03347.1 - 1.2e-09 38.3 0.0 2.2e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 GAN03347.1 - 2.3e-06 27.7 0.0 4.6e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 GAN03347.1 - 9.7e-06 25.8 0.0 2.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 GAN03347.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAN03347.1 - 3.6e-05 24.0 0.3 0.033 14.4 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 GAN03347.1 - 4.8e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAN03347.1 - 0.00012 22.0 0.0 0.00036 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN03347.1 - 0.00013 22.4 0.0 0.0003 21.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GAN03347.1 - 0.00019 21.2 0.0 0.0007 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAN03347.1 - 0.00021 20.6 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAN03347.1 - 0.00035 20.1 0.0 0.00097 18.7 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 GAN03347.1 - 0.00064 19.2 0.0 0.0073 15.7 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein DNA_pol3_delta PF06144.13 GAN03347.1 - 0.00081 19.2 0.2 0.0066 16.3 0.1 2.2 3 0 0 3 3 2 1 DNA polymerase III, delta subunit ResIII PF04851.15 GAN03347.1 - 0.00086 19.3 0.0 0.072 13.1 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAN03347.1 - 0.00094 19.0 0.2 0.01 15.6 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAN03347.1 - 0.0014 19.0 0.2 0.047 14.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 GAN03347.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAN03347.1 - 0.0042 16.2 0.0 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.14 GAN03347.1 - 0.0053 16.8 0.1 0.03 14.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAN03347.1 - 0.015 15.9 0.1 0.1 13.2 0.0 2.2 1 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAN03347.1 - 0.027 14.2 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 GAN03347.1 - 0.031 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_6 PF13174.6 GAN03347.1 - 0.034 14.8 1.0 6.7 7.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 GAN03347.1 - 0.035 13.9 0.0 0.095 12.4 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAN03347.1 - 0.041 13.3 0.1 0.41 10.0 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 GAN03347.1 - 0.046 14.2 0.6 0.087 13.3 0.6 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAN03347.1 - 0.048 13.8 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 GAN03347.1 - 0.048 13.1 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 GAN03347.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 GAN03347.1 - 0.08 12.5 0.1 0.47 10.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAN03347.1 - 0.093 12.6 0.3 2 8.3 0.1 2.7 2 1 0 3 3 3 0 NTPase BrkDBD PF09607.10 GAN03347.1 - 0.11 12.2 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 1 0 Brinker DNA-binding domain SNF2_N PF00176.23 GAN03347.1 - 0.16 10.6 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Oxidored_FMN PF00724.20 GAN03348.1 - 3.1e-99 332.5 0.0 3.6e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ATG11 PF10377.9 GAN03349.1 - 4.9e-33 113.9 0.2 4.9e-33 113.9 0.2 4.0 5 0 0 5 5 5 1 Autophagy-related protein 11 PGM_PMM_I PF02878.16 GAN03349.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I ubiquitin PF00240.23 GAN03349.1 - 0.18 11.6 3.7 1.8 8.4 0.0 3.4 2 1 0 2 2 2 0 Ubiquitin family EloA-BP1 PF15870.5 GAN03350.1 - 0.00082 19.7 0.2 0.0035 17.6 0.1 2.0 1 1 1 2 2 2 1 ElonginA binding-protein 1 RNase_T PF00929.24 GAN03350.1 - 0.05 14.1 0.0 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 Exonuclease Tam41_Mmp37 PF09139.11 GAN03350.1 - 0.06 12.8 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial KIX_2 PF16987.5 GAN03350.1 - 0.074 13.1 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 KIX domain Microvir_lysis PF04517.12 GAN03350.1 - 0.13 12.2 1.1 2 8.4 1.5 2.5 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus MBD PF01429.19 GAN03352.1 - 0.0037 17.0 0.4 0.0049 16.6 0.4 1.2 1 1 0 1 1 1 1 Methyl-CpG binding domain Pkinase PF00069.25 GAN03353.1 - 3.7e-62 210.1 0.0 4.8e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03353.1 - 6.3e-23 81.4 0.0 9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GAN03353.1 - 3.8e-07 30.7 2.1 0.0069 17.2 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN03353.1 - 2.7e-06 27.6 0.0 0.001 19.3 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Kinase-like PF14531.6 GAN03353.1 - 5.6e-06 25.9 0.0 5.5e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAN03353.1 - 0.0056 16.6 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAN03353.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase HAD_SAK_1 PF10307.9 GAN03354.1 - 1.2e-57 195.0 0.0 1.7e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Methyltransf_16 PF10294.9 GAN03355.1 - 7.6e-17 61.6 0.0 9.7e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAN03355.1 - 0.0031 17.4 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAN03355.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 GAN03355.1 - 0.038 13.2 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 GAN03355.1 - 0.14 12.9 0.0 0.37 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PRIMA1 PF16101.5 GAN03356.1 - 1.3 9.1 6.9 0.35 10.9 4.4 1.4 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 Glyco_hydro_20 PF00728.22 GAN03357.1 - 1e-90 304.7 0.8 1.4e-90 304.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAN03357.1 - 2.9e-23 83.0 0.1 9.3e-23 81.4 0.1 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAN03357.1 - 3.9e-07 30.9 0.3 6.4e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GST_C_3 PF14497.6 GAN03358.1 - 2.7e-11 43.5 0.0 4.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAN03358.1 - 1.7e-10 41.2 0.0 3.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAN03358.1 - 7.9e-09 35.6 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAN03358.1 - 2.7e-08 34.0 0.0 5.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAN03358.1 - 3.4e-07 30.2 0.0 4.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAN03358.1 - 8.5e-07 29.2 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CTK3 PF12243.8 GAN03358.1 - 0.099 12.6 0.1 0.27 11.2 0.1 1.7 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 PAP2_3 PF14378.6 GAN03359.1 - 0.055 13.2 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily Glyco_hydro_18 PF00704.28 GAN03360.1 - 1e-59 202.8 3.1 1e-59 202.8 3.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 GAN03360.1 - 0.00082 19.8 9.6 0.00082 19.8 9.6 4.5 4 0 0 4 4 4 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 GAN03360.1 - 0.046 13.7 5.7 0.16 11.9 3.0 2.7 2 0 0 2 2 2 0 Cellulose-binding domain Mucin PF01456.17 GAN03360.1 - 1.3 9.0 34.5 0.18 11.8 29.4 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2946 PF11162.8 GAN03361.1 - 0.2 12.4 0.4 2.5 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Pex24p PF06398.11 GAN03362.1 - 1.4e-36 126.2 10.6 2.6e-36 125.4 10.6 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4112 PF13430.6 GAN03362.1 - 3.1e-25 88.5 0.6 3.1e-25 88.5 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4112) DUF2502 PF10697.9 GAN03362.1 - 0.021 15.2 6.6 0.021 15.2 6.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2502) Mito_carr PF00153.27 GAN03363.1 - 9.9e-80 262.6 0.1 3.7e-28 97.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN03363.1 - 0.0067 15.6 0.8 9.5 5.3 0.0 3.6 1 1 2 4 4 4 3 Gammaproteobacterial serine protease DEAD PF00270.29 GAN03365.1 - 6.1e-52 175.9 0.0 3.3e-50 170.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN03365.1 - 6.8e-26 90.8 2.1 1e-25 90.2 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Pkinase PF00069.25 GAN03366.1 - 1.3e-73 247.6 0.0 1.7e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03366.1 - 1.8e-44 152.0 0.0 2.8e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN03366.1 - 9.3e-10 38.3 0.0 2.6e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 GAN03366.1 - 0.0056 16.2 0.2 0.098 12.2 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.23 GAN03366.1 - 0.0084 16.1 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAN03366.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAN03366.1 - 0.029 13.1 0.6 0.058 12.2 0.6 1.5 1 1 0 1 1 1 0 Fungal protein kinase ATC_hydrolase PF14196.6 GAN03366.1 - 0.077 13.8 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase FTA2 PF13095.6 GAN03366.1 - 0.084 12.5 0.1 0.96 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LIM PF00412.22 GAN03367.1 - 1.2e-47 159.9 41.4 1.4e-14 54.1 3.2 4.2 4 0 0 4 4 4 4 LIM domain zf_UBZ PF18439.1 GAN03367.1 - 0.024 14.2 27.7 0.13 11.9 0.2 6.6 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger WRC PF08879.10 GAN03367.1 - 0.13 12.0 0.3 0.13 12.0 0.3 3.0 3 0 0 3 3 3 0 WRC CymA PF16941.5 GAN03367.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative cyclodextrin porin Zn_ribbon_recom PF13408.6 GAN03367.1 - 4.5 7.9 25.0 3.7 8.2 0.5 4.4 4 0 0 4 4 4 0 Recombinase zinc beta ribbon domain BUD22 PF09073.10 GAN03367.1 - 6.2 6.1 14.1 11 5.2 14.1 1.4 1 0 0 1 1 1 0 BUD22 DZR PF12773.7 GAN03367.1 - 7.9 6.6 36.5 1.7 8.8 3.9 5.0 2 1 2 4 4 4 0 Double zinc ribbon Nucleo_P87 PF07267.11 GAN03367.1 - 8.9 5.0 9.2 13 4.5 9.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AMP-binding PF00501.28 GAN03368.1 - 7.2e-103 344.4 0.0 1e-102 343.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ATP_bind_1 PF03029.17 GAN03369.1 - 1.1e-75 254.6 0.7 1.3e-66 224.8 0.1 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein SPT6_acidic PF14632.6 GAN03369.1 - 0.0052 17.3 5.9 0.0099 16.4 5.9 1.4 1 0 0 1 1 1 1 Acidic N-terminal SPT6 DUF4611 PF15387.6 GAN03369.1 - 0.036 14.3 0.8 0.079 13.2 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FXR_C1 PF16096.5 GAN03369.1 - 2 8.7 10.3 0.67 10.2 7.4 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 PDZ_5 PF17817.1 GAN03370.1 - 0.0023 18.2 0.1 0.0067 16.7 0.1 1.7 1 0 0 1 1 1 1 PDZ domain tRNA_U5-meth_tr PF05958.11 GAN03371.1 - 1.6e-14 53.7 0.8 2.3e-13 49.9 0.8 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAN03371.1 - 2.6e-09 37.1 0.1 6.3e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAN03371.1 - 9.6e-08 31.9 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 GAN03371.1 - 4e-07 29.7 0.1 1.4e-06 28.0 0.1 1.9 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 GAN03371.1 - 4.4e-07 30.5 0.2 1.7e-06 28.6 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 GAN03371.1 - 4.6e-07 29.5 0.1 8.4e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAN03371.1 - 4.1e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GAN03371.1 - 6.6e-05 22.5 1.2 0.00013 21.5 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 GAN03371.1 - 0.00021 21.1 0.1 0.00046 20.0 0.1 1.6 1 0 0 1 1 1 1 Met-10+ like-protein RRM_1 PF00076.22 GAN03371.1 - 0.00052 19.8 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_12 PF08242.12 GAN03371.1 - 0.0078 16.9 0.1 0.022 15.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN03371.1 - 0.01 16.5 0.0 0.033 14.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN03371.1 - 0.013 15.0 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 GAN03371.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 GAN03371.1 - 0.024 14.0 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.8 GAN03371.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_32 PF13679.6 GAN03371.1 - 0.04 13.9 0.6 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.11 GAN03371.1 - 0.04 13.6 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 GAN03371.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ribosomal_L26 PF16906.5 GAN03373.1 - 6.5e-36 122.7 3.5 8.3e-36 122.3 3.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAN03373.1 - 1.3e-10 40.8 2.9 2.7e-10 39.8 2.9 1.6 1 0 0 1 1 1 1 KOW motif DUF1442 PF07279.11 GAN03373.1 - 0.0061 15.9 0.7 0.0079 15.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) P34-Arc PF04045.14 GAN03373.1 - 0.029 14.1 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc RRM_9 PF18444.1 GAN03374.1 - 1.4e-09 37.6 0.0 3.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif PHD PF00628.29 GAN03374.1 - 6.9e-08 32.3 8.0 1.2e-07 31.5 8.0 1.4 1 0 0 1 1 1 1 PHD-finger LRR_9 PF14580.6 GAN03374.1 - 1.8e-07 30.8 1.3 2.2e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 GAN03374.1 - 3.9e-07 30.3 4.5 0.00051 20.4 3.6 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 GAN03374.1 - 1.2e-05 25.9 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 GAN03374.1 - 0.052 13.3 3.8 0.15 11.8 1.5 2.4 1 1 1 2 2 2 0 Leucine rich repeat C1_1 PF00130.22 GAN03374.1 - 5.3 7.0 7.2 0.3 11.0 1.9 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 GAN03374.1 - 7.6 6.9 6.0 5.8 7.3 1.9 2.3 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 GAN03374.1 - 8 6.1 6.8 0.52 9.9 1.7 1.8 2 0 0 2 2 2 0 PHD-finger Pex14_N PF04695.13 GAN03375.1 - 1.4e-18 68.1 6.2 1.4e-18 68.1 6.2 2.9 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PBP_sp32 PF07222.12 GAN03375.1 - 0.021 14.3 0.9 0.036 13.5 0.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Exonuc_VII_L PF02601.15 GAN03375.1 - 0.058 13.0 1.0 0.064 12.8 1.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 GAN03375.1 - 4.4 7.6 8.0 0.3 11.4 2.3 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cation_efflux PF01545.21 GAN03376.1 - 1.2e-49 168.8 16.6 1.6e-49 168.3 16.6 1.2 1 0 0 1 1 1 1 Cation efflux family Metallophos PF00149.28 GAN03376.1 - 8.5e-33 114.6 0.3 1.8e-32 113.5 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DTW PF03942.15 GAN03378.1 - 6.1e-28 97.9 0.0 8.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 DTW domain CybS PF05328.12 GAN03379.1 - 1.8e-36 124.8 0.0 2.5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Med13_C PF06333.12 GAN03379.1 - 0.013 14.8 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Tmemb_14 PF03647.13 GAN03380.1 - 1.3e-24 86.7 4.0 1.5e-24 86.5 4.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 GAN03380.1 - 0.0019 18.5 1.1 0.0044 17.3 1.1 1.7 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Transglut_core2 PF13369.6 GAN03380.1 - 0.098 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF3128 PF11326.8 GAN03381.1 - 9.5e-25 86.8 4.0 1.7e-24 86.0 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) LSM PF01423.22 GAN03381.1 - 2.8e-17 62.1 2.1 4.4e-17 61.5 2.1 1.3 1 0 0 1 1 1 1 LSM domain Peptidase_C6 PF00851.18 GAN03381.1 - 0.027 13.4 0.3 0.038 12.9 0.3 1.1 1 0 0 1 1 1 0 Helper component proteinase SM-ATX PF14438.6 GAN03381.1 - 0.09 12.9 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Ataxin 2 SM domain UPF0203 PF05254.12 GAN03381.1 - 0.21 11.9 6.0 0.42 10.9 6.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) zf-C2H2 PF00096.26 GAN03382.1 - 6.3e-06 26.4 6.5 0.0041 17.5 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN03382.1 - 0.00055 20.6 8.3 0.035 14.9 0.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN03382.1 - 0.0048 17.3 2.0 0.0048 17.3 2.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 GAN03382.1 - 0.022 14.5 1.9 0.022 14.5 1.9 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 GAN03382.1 - 0.048 14.1 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type F-box-like PF12937.7 GAN03383.1 - 0.00054 19.8 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03383.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain Allantoicase PF03561.15 GAN03384.1 - 1.9e-53 180.3 0.0 1.6e-27 96.3 0.0 2.3 2 0 0 2 2 2 2 Allantoicase repeat DENN PF02141.21 GAN03385.1 - 2.1e-44 151.7 0.1 4.3e-44 150.7 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 GAN03385.1 - 4.9e-14 52.1 3.3 1.2e-13 50.8 3.3 1.8 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 GAN03385.1 - 6.8e-14 52.4 3.0 6.8e-14 52.4 3.0 2.6 3 0 0 3 3 3 1 uDENN domain C1_1 PF00130.22 GAN03385.1 - 0.23 11.4 5.5 0.61 10.0 5.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PI3_PI4_kinase PF00454.27 GAN03386.1 - 7.7e-52 176.6 0.0 3e-51 174.7 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAN03386.1 - 5.8e-14 52.1 6.8 5.8e-14 52.1 6.8 2.0 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 GAN03386.1 - 4.2e-09 36.1 1.0 3.1e-08 33.3 0.1 2.6 2 0 0 2 2 2 1 FATC domain UME PF08064.13 GAN03386.1 - 7.3e-07 29.0 0.6 3.7e-06 26.8 0.3 2.5 2 0 0 2 2 2 1 UME (NUC010) domain DUF3385 PF11865.8 GAN03386.1 - 0.0049 16.8 2.9 0.095 12.6 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) DUF2999 PF11212.8 GAN03386.1 - 0.085 13.1 0.2 21 5.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) Urb2 PF10441.9 GAN03386.1 - 0.23 11.3 2.6 1.3 8.9 0.2 2.7 2 0 0 2 2 2 0 Urb2/Npa2 family Dynactin_p22 PF07426.11 GAN03387.1 - 1.8e-45 154.8 2.9 2.6e-45 154.3 2.9 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 NPV_P10 PF05531.12 GAN03387.1 - 0.0012 19.3 3.4 0.03 14.8 0.3 2.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAN03387.1 - 0.023 14.7 3.8 3.3 7.7 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 GAN03387.1 - 0.043 13.2 3.4 0.63 9.4 0.2 2.7 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Retrotrans_gag PF03732.17 GAN03387.1 - 0.067 13.5 1.1 5.2 7.4 0.1 2.4 3 0 0 3 3 2 0 Retrotransposon gag protein KLRAQ PF10205.9 GAN03387.1 - 0.08 13.2 1.2 0.12 12.7 0.1 1.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein Nsp1_C PF05064.13 GAN03387.1 - 0.088 12.6 3.7 3 7.7 0.5 3.0 1 1 2 3 3 3 0 Nsp1-like C-terminal region Thioredoxin_8 PF13905.6 GAN03387.1 - 0.09 13.1 1.6 0.17 12.3 0.2 2.0 2 1 0 2 2 2 0 Thioredoxin-like Mt_ATP-synt_B PF05405.14 GAN03387.1 - 0.11 12.1 2.4 0.28 10.8 0.3 2.3 1 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Tup_N PF08581.10 GAN03387.1 - 0.13 12.6 3.2 0.85 10.0 1.2 3.0 2 1 0 2 2 2 0 Tup N-terminal Mod_r PF07200.13 GAN03387.1 - 0.2 11.8 3.9 0.62 10.2 1.7 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.9 GAN03387.1 - 0.44 10.9 5.2 0.75 10.1 0.2 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fungal_TACC PF12709.7 GAN03387.1 - 0.45 11.0 4.5 7.3 7.1 0.3 3.3 1 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins LRR_6 PF13516.6 GAN03388.1 - 4.4e-07 29.4 9.8 0.21 11.7 0.1 6.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 GAN03388.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 7.4 4 3 5 9 9 9 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 GAN03388.1 - 8.8 6.7 13.4 46 4.5 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 GAN03389.1 - 3.3e-40 136.9 0.0 4.8e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAN03389.1 - 8.3e-16 58.0 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAN03389.1 - 1e-12 47.7 0.1 1.9e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Allantoicase PF03561.15 GAN03390.1 - 1.9e-44 151.2 0.0 1.2e-21 77.3 0.0 3.1 3 0 0 3 3 3 2 Allantoicase repeat Pex14_N PF04695.13 GAN03390.1 - 1.8 9.2 14.1 2.6 8.7 13.0 1.8 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 GAN03390.1 - 1.9 7.1 5.6 2.6 6.7 5.6 1.2 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 GAN03390.1 - 2.8 6.8 5.4 4 6.3 5.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TRAPP PF04051.16 GAN03391.1 - 2.9e-48 163.3 0.0 3.5e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SUI1 PF01253.22 GAN03392.1 - 1.3e-18 67.3 0.5 5.1e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 GAN03392.1 - 4.7e-12 46.4 0.1 1.8e-10 41.3 0.0 3.1 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 GAN03392.1 - 0.00032 20.6 0.0 0.00071 19.5 0.0 1.6 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.9 GAN03392.1 - 0.0019 18.1 0.0 0.0066 16.4 0.0 1.9 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 GAN03392.1 - 0.0021 17.9 0.3 0.0058 16.5 0.3 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain RXT2_N PF08595.11 GAN03392.1 - 1.2 9.1 8.0 0.51 10.3 0.7 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Abhydrolase_3 PF07859.13 GAN03393.1 - 5.8e-18 65.5 0.0 1.2e-17 64.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 GAN03393.1 - 5.6e-17 61.8 0.2 5.6e-16 58.5 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAN03393.1 - 1.6e-08 34.3 0.0 0.00032 20.2 0.0 2.9 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAN03393.1 - 0.00011 21.3 0.0 0.00019 20.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GAN03393.1 - 0.00015 21.1 0.0 0.0027 17.0 0.0 2.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN03393.1 - 0.0002 22.1 0.0 0.00041 21.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 GAN03393.1 - 0.031 12.8 0.0 0.097 11.2 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PAH PF02671.21 GAN03393.1 - 0.12 12.5 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat DUF1700 PF08006.11 GAN03393.1 - 2.4 7.6 4.5 4.5 6.8 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SAP PF02037.27 GAN03394.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain ATP-synt_G PF04718.15 GAN03394.1 - 0.046 14.5 0.0 1.2 10.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit DUF2624 PF11116.8 GAN03394.1 - 0.055 14.4 0.4 0.39 11.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2624) Rho_N PF07498.12 GAN03394.1 - 0.081 12.9 0.6 0.21 11.5 0.6 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Usp PF00582.26 GAN03395.1 - 1.7e-21 77.2 0.1 2.3e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family FBP_C PF16571.5 GAN03395.1 - 0.013 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger DAGK_acc PF00609.19 GAN03396.1 - 2.2e-17 63.8 0.0 4.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GAN03396.1 - 2.8e-11 43.1 0.0 3.4e-10 39.6 0.0 2.3 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4743 PF15916.5 GAN03397.1 - 7.9e-20 71.0 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 GAN03397.1 - 2.6e-07 30.7 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MaoC_dehydratas PF01575.19 GAN03398.1 - 5.1e-28 97.1 0.0 9e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAN03398.1 - 3.9e-06 27.0 0.0 5.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase PigN PF04987.14 GAN03399.1 - 3.3e-136 454.8 48.8 5.8e-136 454.0 48.8 1.4 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) HIG_1_N PF04588.13 GAN03399.1 - 5.9e-17 61.6 2.1 5.9e-17 61.6 2.1 2.9 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Phosphodiest PF01663.22 GAN03399.1 - 4.8e-10 39.5 0.8 1.5e-09 38.0 0.8 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase BUD22 PF09073.10 GAN03400.1 - 1.3 8.3 20.2 3.2 7.0 20.2 1.6 1 0 0 1 1 1 0 BUD22 GMC_oxred_N PF00732.19 GAN03401.1 - 3.3e-68 230.2 0.1 1e-67 228.6 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAN03401.1 - 4.3e-31 108.4 0.0 7.8e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAN03401.1 - 0.00015 21.9 0.3 0.00044 20.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAN03401.1 - 0.001 18.2 0.1 0.002 17.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAN03401.1 - 0.0015 18.2 0.2 0.0045 16.6 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN03401.1 - 0.0017 17.7 0.0 0.0056 15.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAN03401.1 - 0.0022 17.1 0.1 0.0038 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAN03401.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 GAN03401.1 - 0.027 13.5 0.2 0.064 12.3 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAN03401.1 - 0.034 12.8 0.0 0.071 11.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 GAN03401.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 GAN03401.1 - 0.053 12.8 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAN03401.1 - 0.061 12.2 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 GAN03401.1 - 0.061 13.9 0.3 0.23 12.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YjeJ PF15922.5 GAN03401.1 - 0.07 12.3 0.1 8.6 5.5 0.0 2.2 2 0 0 2 2 2 0 YjeJ-like HHH_5 PF14520.6 GAN03401.1 - 0.19 12.4 0.3 0.57 10.8 0.3 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain IDO PF01231.18 GAN03402.1 - 1.1e-43 149.6 0.0 1.4e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ApbA_C PF08546.11 GAN03402.1 - 0.011 15.9 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal MRP-S33 PF08293.11 GAN03403.1 - 2.9e-28 97.9 0.1 3.5e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 GATA PF00320.27 GAN03404.1 - 2.1e-13 49.6 6.3 5.7e-13 48.2 6.3 1.7 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 GAN03404.1 - 0.3 11.2 1.7 0.64 10.2 0.4 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Cut8 PF08559.10 GAN03405.1 - 6.7e-58 196.1 2.2 8.5e-58 195.8 2.2 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein CLTH PF10607.9 GAN03405.1 - 0.017 15.0 0.0 0.061 13.2 0.0 1.9 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain HxlR PF01638.17 GAN03405.1 - 0.093 12.6 0.0 13 5.7 0.2 2.4 1 1 1 2 2 2 0 HxlR-like helix-turn-helix EF-hand_7 PF13499.6 GAN03406.1 - 6.1e-08 33.0 3.0 0.00024 21.5 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAN03406.1 - 1e-07 31.0 0.0 1e-06 27.8 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GAN03406.1 - 1.3e-05 24.7 0.1 0.0059 16.4 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GAN03406.1 - 4.3e-05 23.3 0.8 0.00038 20.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GAN03406.1 - 0.00025 20.4 0.0 0.00078 18.8 0.0 1.9 1 0 0 1 1 1 1 EF hand Polyoma_coat2 PF00761.20 GAN03407.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Polyomavirus coat protein ALMT PF11744.8 GAN03409.1 - 0.11 11.3 11.1 0.12 11.2 10.3 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter Asp-B-Hydro_N PF05279.11 GAN03409.1 - 1.7 8.7 9.0 2.3 8.2 9.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Macoilin PF09726.9 GAN03409.1 - 1.9 6.9 17.7 2.2 6.7 17.7 1.1 1 0 0 1 1 1 0 Macoilin family PQ-loop PF04193.14 GAN03410.1 - 3.6e-33 113.1 5.4 1.8e-18 66.0 1.5 2.6 2 0 0 2 2 2 2 PQ loop repeat Beta_elim_lyase PF01212.21 GAN03411.1 - 2.7e-74 250.1 0.1 3.5e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAN03411.1 - 0.0082 15.5 0.0 0.04 13.2 0.0 2.0 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 GAN03411.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Ppx-GppA PF02541.16 GAN03412.1 - 9.7e-43 146.6 0.0 1.8e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family AF-4 PF05110.13 GAN03412.1 - 9.9 4.1 12.6 15 3.5 12.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Polysacc_deac_1 PF01522.21 GAN03413.1 - 2.1e-24 85.8 0.0 4.3e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase HMG_box PF00505.19 GAN03414.1 - 1.9e-17 63.4 3.6 3.2e-17 62.7 3.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN03414.1 - 4.7e-08 33.5 2.3 4.7e-08 33.5 2.3 1.6 2 0 0 2 2 2 1 HMG-box domain COX4 PF02936.14 GAN03414.1 - 0.0074 16.3 0.5 0.016 15.2 0.5 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Oxidored_FMN PF00724.20 GAN03415.1 - 1.6e-98 330.2 0.0 1.8e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Polysacc_deac_1 PF01522.21 GAN03417.1 - 2.9e-23 82.1 0.0 5.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Vps51 PF08700.11 GAN03418.1 - 1e-14 54.3 0.9 7.8e-13 48.3 0.2 3.3 2 0 0 2 2 2 1 Vps51/Vps67 HTH_ABP1_N PF18107.1 GAN03418.1 - 0.016 14.9 2.8 0.51 10.1 0.8 3.3 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Sec5 PF15469.6 GAN03418.1 - 0.49 10.2 11.6 0.097 12.5 1.4 4.1 3 2 1 4 4 4 0 Exocyst complex component Sec5 FliT PF05400.13 GAN03418.1 - 1.7 9.5 5.3 3 8.7 0.3 3.8 4 0 0 4 4 4 0 Flagellar protein FliT BAF250_C PF12031.8 GAN03419.1 - 1.3e-05 24.7 1.1 1.3e-05 24.7 1.1 3.0 2 1 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa VPS13_mid_rpt PF16910.5 GAN03420.1 - 1.1e-87 293.4 18.6 6e-85 284.4 1.3 5.8 6 1 0 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 GAN03420.1 - 9.1e-77 258.0 0.5 3e-75 253.1 0.1 3.6 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 GAN03420.1 - 8.4e-71 238.5 5.3 7e-69 232.2 0.2 3.3 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 GAN03420.1 - 1.9e-67 226.5 5.7 6.6e-64 214.9 0.1 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 GAN03420.1 - 1.1e-34 119.0 0.9 1.6e-19 70.1 0.2 3.3 3 0 0 3 3 3 2 N-terminal region of Chorein or VPS13 HMG_box PF00505.19 GAN03420.1 - 7.9e-14 51.8 2.3 6.7e-07 29.6 0.1 2.9 1 1 1 2 2 2 2 HMG (high mobility group) box ATG_C PF09333.11 GAN03420.1 - 1.3e-07 31.9 0.0 5.2e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain HMG_box_2 PF09011.10 GAN03420.1 - 2.5e-07 31.2 0.6 0.011 16.3 0.1 3.1 1 1 1 2 2 2 2 HMG-box domain CDT1 PF08839.11 GAN03421.1 - 9.1e-09 35.8 0.3 9.1e-09 35.8 0.3 2.2 2 2 0 2 2 2 1 DNA replication factor CDT1 like MIF4G PF02854.19 GAN03422.1 - 1.1e-42 146.1 1.2 1.1e-42 146.1 1.2 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 GAN03422.1 - 3.4e-14 52.8 0.7 8.7e-14 51.5 0.7 1.7 1 0 0 1 1 1 1 MA3 domain eIF_4G1 PF12152.8 GAN03422.1 - 8e-09 35.6 0.1 3.3e-08 33.6 0.1 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 KKLCAg1 PF15204.6 GAN03423.1 - 0.0018 18.3 0.6 0.0023 18.0 0.6 1.1 1 0 0 1 1 1 1 Kita-kyushu lung cancer antigen 1 DUF1712 PF08217.11 GAN03423.1 - 0.012 14.1 1.1 0.014 13.9 1.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Nop PF01798.18 GAN03423.1 - 0.02 14.3 0.4 0.025 14.0 0.4 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin F-box-like PF12937.7 GAN03424.1 - 0.00051 19.9 0.0 0.00099 19.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like Oxidored_FMN PF00724.20 GAN03425.1 - 1.7e-102 343.2 0.0 1.9e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M22 PF00814.25 GAN03426.1 - 1.1e-81 274.5 0.0 1.3e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 GAN03426.1 - 0.024 14.3 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus RhoGEF PF00621.20 GAN03427.1 - 1.2e-27 97.3 0.2 2.2e-27 96.5 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain Pkinase PF00069.25 GAN03428.1 - 2.3e-74 250.1 0.0 3e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03428.1 - 1.1e-35 123.2 0.0 1.7e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN03428.1 - 3.9e-07 29.7 0.0 9.7e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAN03428.1 - 0.0048 16.5 0.1 0.09 12.4 0.1 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 GAN03428.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 zf-Nse PF11789.8 GAN03429.1 - 5.9e-05 22.8 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF489 PF04356.12 GAN03429.1 - 0.092 12.7 0.4 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) MFS_1 PF07690.16 GAN03430.1 - 2.8e-35 121.9 72.6 3.5e-29 101.8 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FmdE PF02663.14 GAN03431.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon NOA36 PF06524.12 GAN03431.1 - 0.83 8.9 21.9 1.2 8.4 21.9 1.2 1 0 0 1 1 1 0 NOA36 protein Fasciclin PF02469.22 GAN03432.1 - 4.4e-68 227.4 6.6 3.4e-21 75.8 1.0 5.6 5 1 0 5 5 5 5 Fasciclin domain ArsB PF02040.15 GAN03432.1 - 0.04 13.3 0.6 0.063 12.6 0.6 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein cobW PF02492.19 GAN03433.1 - 6.8e-49 165.8 0.8 1e-48 165.2 0.8 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAN03433.1 - 3.8e-11 42.8 0.0 7.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAN03433.1 - 0.00024 21.0 1.8 0.56 10.1 0.3 2.6 2 1 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 GAN03433.1 - 0.0041 16.2 1.1 0.015 14.3 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 GAN03433.1 - 0.0075 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAN03433.1 - 0.0082 16.1 0.0 0.0082 16.1 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 GAN03433.1 - 0.018 15.1 0.2 0.095 12.8 0.0 2.2 1 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAN03433.1 - 0.039 14.3 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 GAN03433.1 - 0.04 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GAN03433.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 GAN03433.1 - 0.056 13.2 0.2 0.13 12.0 0.2 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 GAN03433.1 - 0.056 14.0 1.2 0.17 12.4 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 GAN03433.1 - 0.09 12.5 0.1 0.29 10.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAN03433.1 - 0.096 13.2 1.0 0.23 12.0 0.8 2.1 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 GAN03433.1 - 1.5 8.3 7.7 9.8 5.7 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 GAN03433.1 - 1.8 9.0 8.2 3.6 8.0 1.2 2.8 2 1 1 3 3 3 0 AAA domain Glyco_transf_20 PF00982.21 GAN03434.1 - 1.3e-154 515.4 0.6 2.1e-154 514.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN03434.1 - 7.8e-77 257.5 0.1 4e-76 255.2 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase zf-RING_11 PF17123.5 GAN03434.1 - 9.9e-08 31.6 7.1 2.5e-07 30.3 7.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger Hydrolase_3 PF08282.12 GAN03434.1 - 1.9e-06 27.8 0.0 0.00078 19.2 0.0 2.7 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 GAN03434.1 - 9.3e-05 22.7 4.7 0.00026 21.3 4.7 1.8 1 0 0 1 1 1 1 Ring finger domain S6PP PF05116.13 GAN03434.1 - 0.001 18.7 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase PA PF02225.22 GAN03434.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 GAN03434.1 - 0.011 15.6 4.0 0.032 14.1 4.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN03434.1 - 0.05 13.5 5.0 0.13 12.1 5.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EF1G PF00647.19 GAN03435.1 - 1.7e-22 79.5 0.0 4.2e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 GAN03435.1 - 1.4e-14 54.2 0.8 8.9e-14 51.6 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAN03435.1 - 3.6e-12 46.3 0.0 9.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAN03435.1 - 2.2e-09 37.4 0.0 7.3e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAN03435.1 - 2.3e-08 34.4 0.0 5.5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN03435.1 - 5.4e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAN03435.1 - 2.7e-05 24.1 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAN03435.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 GAN03435.1 - 0.35 11.5 4.3 1.1 9.9 4.3 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Fungal_trans PF04082.18 GAN03436.1 - 9.4e-21 74.0 0.8 2.3e-20 72.7 0.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 GAN03436.1 - 1.8e-20 72.8 6.8 0.0016 19.2 0.4 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Zn_clus PF00172.18 GAN03436.1 - 2.8e-08 33.7 16.3 7.2e-08 32.4 16.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC4_WD40 PF12894.7 GAN03436.1 - 5.3e-06 26.6 2.5 1.1 9.6 0.1 4.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAN03436.1 - 0.0071 16.4 0.3 0.2 11.7 0.0 3.2 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region YL1 PF05764.13 GAN03436.1 - 0.26 11.4 18.4 0.026 14.6 12.7 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Dicty_REP PF05086.12 GAN03436.1 - 2.5 6.0 15.7 4.9 5.0 15.7 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GARS_A PF01071.19 GAN03441.1 - 1.7e-83 279.2 0.0 3e-83 278.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 GAN03441.1 - 1.1e-34 119.9 0.0 2.4e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 GAN03441.1 - 5.1e-34 116.9 0.1 1.6e-33 115.4 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 GAN03441.1 - 2.7e-30 104.5 1.0 5.5e-30 103.5 1.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 GAN03441.1 - 1.1e-13 51.6 2.4 2.8e-13 50.3 0.5 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 GAN03441.1 - 0.00029 20.5 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAN03441.1 - 0.0015 18.6 0.0 0.0051 16.9 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAN03441.1 - 0.002 17.8 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 GAN03441.1 - 0.0079 15.7 0.2 0.019 14.4 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 GAN03441.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 GAN03441.1 - 0.071 12.7 0.1 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 ATP-grasp domain Pes-10 PF07149.11 GAN03442.1 - 0.87 8.6 6.2 1.3 8.0 6.2 1.2 1 0 0 1 1 1 0 Pes-10 Fungal_trans PF04082.18 GAN03444.1 - 2.3e-27 95.7 0.2 3e-26 92.0 0.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4746 PF15928.5 GAN03444.1 - 0.06 12.8 3.6 0.1 12.0 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MID_MedPIWI PF18296.1 GAN03444.1 - 0.11 12.2 10.5 0.016 15.0 4.7 2.1 2 0 0 2 2 2 0 MID domain of medPIWI TFIIA PF03153.13 GAN03444.1 - 0.19 11.7 24.5 0.084 12.9 20.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 GAN03444.1 - 2.8 6.1 16.6 4.4 5.5 16.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Baculo_PP31 PF05311.11 GAN03444.1 - 4.2 6.8 7.7 0.78 9.2 2.9 1.9 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.8 GAN03444.1 - 6.2 6.4 27.7 11 5.6 27.7 1.3 1 0 0 1 1 1 0 Spt20 family Tim54 PF11711.8 GAN03444.1 - 6.3 5.5 8.2 10 4.8 8.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.12 GAN03444.1 - 6.6 6.0 11.6 13 5.1 11.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 GAN03444.1 - 6.6 5.4 8.2 11 4.6 8.2 1.3 1 0 0 1 1 1 0 Presenilin Exo_endo_phos_2 PF14529.6 GAN03445.1 - 1.3e-14 54.1 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN03445.1 - 0.0054 16.3 0.0 0.026 14.1 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 GAN03446.1 - 2.1e-09 37.2 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VASt PF16016.5 GAN03446.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain HELP PF03451.14 GAN03447.1 - 0.21 11.4 6.6 2.2 8.2 0.4 3.0 2 1 1 3 3 3 0 HELP motif YvrJ PF12841.7 GAN03447.1 - 0.38 10.3 12.3 3.6 7.2 0.6 3.4 3 0 0 3 3 3 0 YvrJ protein family GPI-anchored PF10342.9 GAN03448.1 - 2.6e-12 47.3 3.8 2.6e-12 47.3 3.8 2.2 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5626 PF18540.1 GAN03448.1 - 5.3 7.6 12.8 0.19 12.2 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5626) Med20 PF08612.11 GAN03449.1 - 1.1e-32 113.3 0.2 1.2e-32 113.1 0.2 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_63N PF16923.5 GAN03449.1 - 0.02 15.0 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain TruD PF01142.18 GAN03450.1 - 1.2e-71 241.8 0.0 3.5e-69 233.6 0.0 2.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Ins_allergen_rp PF06757.13 GAN03450.1 - 0.065 13.2 0.1 0.31 11.0 0.1 2.1 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Uricase PF01014.18 GAN03451.1 - 1.1e-67 226.3 2.8 8.3e-33 113.4 0.7 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 GAN03451.1 - 0.059 13.9 0.2 0.72 10.4 0.1 2.1 2 0 0 2 2 2 0 Dihydroneopterin aldolase Ribosomal_L17 PF01196.19 GAN03451.1 - 0.071 14.0 0.0 0.16 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L17 GlcV_C_terminal PF17847.1 GAN03451.1 - 0.08 13.4 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Glucose ABC transporter C-terminal domain Tox-REase-9 PF15650.6 GAN03451.1 - 0.1 12.9 0.0 0.5 10.7 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 9 WD40 PF00400.32 GAN03452.1 - 1.5e-45 152.2 18.0 6.3e-09 36.3 0.3 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Glucosamine_iso PF01182.20 GAN03452.1 - 2.1e-19 70.3 0.0 4.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ANAPC4_WD40 PF12894.7 GAN03452.1 - 1.6e-17 63.6 6.3 0.0014 18.9 0.3 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN03452.1 - 3e-08 33.8 3.5 0.0028 17.6 0.3 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAN03452.1 - 0.0016 17.8 0.0 1.1 8.6 0.0 2.6 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 GAN03452.1 - 0.027 13.4 0.6 1.9 7.4 0.1 2.4 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HA2 PF04408.23 GAN03453.1 - 9.5e-21 74.1 0.0 1.9e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAN03453.1 - 3.5e-20 72.1 0.0 8.9e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAN03453.1 - 6.7e-14 52.2 0.0 2.3e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN03453.1 - 7.7e-09 35.6 0.4 3.1e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAN03453.1 - 0.00018 21.8 0.2 0.00075 19.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAN03453.1 - 0.00023 20.9 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN03453.1 - 0.00027 21.2 0.0 0.00073 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAN03453.1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 GAN03453.1 - 0.016 14.8 0.1 0.038 13.6 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 GAN03453.1 - 0.028 13.9 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAN03453.1 - 0.15 12.6 0.3 1.2 9.7 0.3 2.3 1 1 0 1 1 1 0 ABC transporter tRNA-synt_2 PF00152.20 GAN03454.1 - 2.8e-94 315.7 0.0 3.4e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAN03454.1 - 1.4e-09 37.8 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAN03454.1 - 0.04 13.4 0.0 2.2 7.7 0.0 2.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Gluconate_2-dh3 PF13618.6 GAN03454.1 - 0.13 12.5 0.1 0.68 10.2 0.0 2.1 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Porin_3 PF01459.22 GAN03455.1 - 3.9e-69 233.1 1.7 4.6e-69 232.9 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Urocanase_C PF17392.2 GAN03455.1 - 0.088 12.2 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Urocanase C-terminal domain HECT PF00632.25 GAN03456.1 - 7e-95 318.0 0.0 1e-94 317.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 GAN03456.1 - 2.4e-35 120.3 21.9 1.6e-12 47.2 0.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 GAN03456.1 - 2.3e-20 72.8 0.4 7.5e-20 71.1 0.4 2.0 1 0 0 1 1 1 1 C2 domain ABC_membrane PF00664.23 GAN03459.1 - 1.3e-118 395.6 25.0 2.9e-61 207.5 13.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN03459.1 - 1.3e-68 229.8 2.6 1.3e-34 119.7 0.1 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAN03459.1 - 2.8e-13 49.8 6.5 3.7e-06 26.5 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAN03459.1 - 1.1e-09 38.9 3.5 0.0012 19.2 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAN03459.1 - 6.9e-09 36.1 0.7 0.0011 19.2 0.1 3.7 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 GAN03459.1 - 2.9e-07 29.7 0.9 0.01 14.7 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAN03459.1 - 3.4e-06 27.1 0.1 0.096 12.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAN03459.1 - 4.8e-06 26.2 0.6 0.052 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 GAN03459.1 - 1.2e-05 25.2 6.7 0.014 15.1 0.1 4.4 2 2 0 3 3 3 2 AAA domain AAA PF00004.29 GAN03459.1 - 1.7e-05 25.3 5.6 0.56 10.6 0.1 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAN03459.1 - 2.3e-05 24.4 0.0 0.019 14.9 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 GAN03459.1 - 0.00011 21.8 0.0 0.59 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAN03459.1 - 0.00021 20.7 0.2 0.11 11.8 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.20 GAN03459.1 - 0.00021 20.6 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 GAN03459.1 - 0.0004 20.5 0.0 0.24 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAN03459.1 - 0.00043 20.2 0.5 1.6 8.5 0.0 3.9 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAN03459.1 - 0.00051 20.6 5.7 0.16 12.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAN03459.1 - 0.0018 18.9 0.0 4 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAN03459.1 - 0.0027 17.5 0.0 0.41 10.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 GAN03459.1 - 0.0029 17.5 0.9 0.16 11.8 0.0 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase SbcCD_C PF13558.6 GAN03459.1 - 0.0036 17.5 5.1 3.7 7.8 0.8 4.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 GAN03459.1 - 0.0039 17.6 0.2 5.4 7.5 0.0 3.5 4 0 0 4 4 2 0 RNA helicase SRP54 PF00448.22 GAN03459.1 - 0.0039 16.8 0.2 0.97 9.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 GAN03459.1 - 0.0044 17.0 1.0 7.7 6.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAN03459.1 - 0.0053 17.0 1.7 1.8 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 GAN03459.1 - 0.007 15.5 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 GAN03459.1 - 0.0081 15.9 0.0 3 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 GAN03459.1 - 0.014 15.1 0.4 5.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase ATP_bind_1 PF03029.17 GAN03459.1 - 0.019 14.8 0.1 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 GAN03459.1 - 0.024 14.7 1.2 12 6.1 0.2 3.8 3 1 0 3 3 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 GAN03459.1 - 0.025 14.1 0.3 7.7 6.0 0.2 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 GAN03459.1 - 0.05 12.8 0.7 3.3 6.8 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain Dala_Dala_lig_N PF01820.21 GAN03459.1 - 0.063 13.8 0.0 3.3 8.2 0.0 2.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Mg_chelatase PF01078.21 GAN03459.1 - 0.063 12.7 0.0 11 5.3 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 GAN03459.1 - 0.09 12.5 0.0 6.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.7 GAN03459.1 - 0.14 11.0 1.6 4.4 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain IstB_IS21 PF01695.17 GAN03459.1 - 0.15 11.8 3.2 22 4.7 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_17 PF13207.6 GAN03459.1 - 0.71 10.3 4.1 20 5.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain MDFI PF15316.6 GAN03460.1 - 0.0045 17.1 0.1 0.0046 17.1 0.1 1.2 1 0 0 1 1 1 1 MyoD family inhibitor CYSTM PF12734.7 GAN03460.1 - 0.37 11.1 7.6 0.85 10.0 7.6 1.7 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance HMG_box PF00505.19 GAN03463.1 - 9.2e-18 64.4 10.1 2.7e-09 37.3 0.6 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN03463.1 - 2.3e-15 56.9 7.1 3.8e-08 33.8 0.7 2.4 2 0 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 GAN03463.1 - 0.00027 21.1 4.0 0.01 16.1 0.2 2.1 1 1 1 2 2 2 2 Protamine and protamine like DUF3106 PF11304.8 GAN03463.1 - 0.0058 17.1 4.7 0.026 15.0 1.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3106) Flu_PA PF00603.17 GAN03463.1 - 0.006 14.8 1.7 0.0068 14.6 1.7 1.1 1 0 0 1 1 1 1 Influenza RNA-dependent RNA polymerase subunit PA RRM_1 PF00076.22 GAN03464.1 - 6e-20 70.8 0.0 1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN03464.1 - 6.5e-06 26.2 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 GAN03464.1 - 0.00031 20.3 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAP1C PF05609.12 GAN03464.1 - 2.8 6.9 12.4 3.2 6.7 12.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 GAN03464.1 - 4.1 6.2 20.0 5.7 5.7 20.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Frigida PF07899.11 GAN03465.1 - 0.19 10.9 0.1 0.21 10.9 0.1 1.1 1 0 0 1 1 1 0 Frigida-like protein MutS_V PF00488.21 GAN03466.1 - 1.8e-72 243.3 0.6 3.4e-72 242.5 0.6 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAN03466.1 - 6.5e-36 124.3 0.3 1.8e-35 122.9 0.3 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAN03466.1 - 2.1e-28 98.8 0.0 1.1e-27 96.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 GAN03466.1 - 6.5e-15 55.6 0.0 2.2e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 MutS domain II Cu-oxidase_2 PF07731.14 GAN03466.1 - 2.3e-14 53.3 10.8 5.8e-11 42.3 4.5 3.5 2 2 1 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAN03466.1 - 1.6e-06 28.1 1.7 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase MutS_IV PF05190.18 GAN03466.1 - 1e-05 25.8 1.6 1e-05 25.8 1.6 2.1 2 0 0 2 2 2 1 MutS family domain IV YjcQ PF09639.10 GAN03466.1 - 0.096 12.9 0.2 0.5 10.6 0.1 2.2 3 0 0 3 3 3 0 YjcQ protein DUF4911 PF16256.5 GAN03466.1 - 0.15 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) AA_permease_2 PF13520.6 GAN03467.1 - 4.9e-66 223.3 48.6 4.9e-66 223.3 48.6 1.8 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 GAN03467.1 - 5.2e-25 88.0 42.3 7.8e-25 87.4 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease DASH_Duo1 PF08651.10 GAN03468.1 - 3.5e-18 65.1 0.9 4.6e-18 64.8 0.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 GAN03468.1 - 0.00012 22.5 0.6 0.00019 21.8 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Rpp20 PF12328.8 GAN03468.1 - 0.0076 16.2 0.2 0.012 15.6 0.2 1.3 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P BLOC1_2 PF10046.9 GAN03468.1 - 0.037 14.3 0.4 0.055 13.8 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GAN03468.1 - 0.061 13.8 1.4 0.14 12.6 1.1 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ER PF01133.17 GAN03468.1 - 0.089 12.8 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Enhancer of rudimentary UPF0184 PF03670.13 GAN03468.1 - 0.1 13.0 1.8 0.21 12.0 0.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) HATPase_c PF02518.26 GAN03469.1 - 3.8e-29 101.5 1.3 1.2e-28 99.9 1.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAN03469.1 - 1.8e-18 66.3 0.0 5.9e-18 64.7 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 GAN03469.1 - 1.9e-17 63.5 0.0 5.2e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 GAN03469.1 - 5e-16 59.6 0.7 1.5e-15 58.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Pkinase PF00069.25 GAN03469.1 - 6.8e-09 35.5 0.0 3e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain GAF_2 PF13185.6 GAN03469.1 - 9.7e-09 35.6 0.0 1.9e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 GAN03469.1 - 5e-08 33.6 0.0 1.2e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 GAN03469.1 - 1.1e-05 25.8 0.0 3.5e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 GAN03469.1 - 0.0016 18.3 0.1 0.0072 16.2 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NACHT PF05729.12 GAN03469.1 - 0.0075 16.2 1.4 0.033 14.1 1.4 2.2 1 1 0 1 1 1 1 NACHT domain Peripla_BP_3 PF13377.6 GAN03469.1 - 0.02 15.2 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 Periplasmic binding protein-like domain RsgA_GTPase PF03193.16 GAN03469.1 - 0.024 14.5 0.5 0.23 11.3 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase Pkinase_Tyr PF07714.17 GAN03469.1 - 0.06 12.6 0.0 5.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein tyrosine kinase AlaDh_PNT_N PF05222.15 GAN03469.1 - 0.097 13.0 0.1 9.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain NB-ARC PF00931.22 GAN03469.1 - 0.13 11.4 0.6 1.2 8.3 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain NUDIX PF00293.28 GAN03471.1 - 4.2e-12 46.2 0.0 5.5e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain SRP-alpha_N PF04086.13 GAN03472.1 - 0.74 9.7 28.5 0.88 9.4 28.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF572 PF04502.13 GAN03472.1 - 8.3 5.9 35.3 9.9 5.7 35.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Methyltransf_8 PF05148.15 GAN03473.1 - 7.6e-81 271.1 1.5 1.4e-79 267.0 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GAN03473.1 - 7.4e-08 32.9 0.7 4e-07 30.6 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN03473.1 - 7.8e-06 26.5 0.7 0.0007 20.3 0.1 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN03473.1 - 0.00038 19.9 0.1 0.0011 18.3 0.1 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAN03473.1 - 0.00072 19.1 0.3 0.04 13.5 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAN03473.1 - 1.9 8.4 0.0 1.9 8.4 0.0 3.2 2 1 0 2 2 2 0 Methyltransferase domain DNA_ligase_A_M PF01068.21 GAN03474.1 - 7.6e-19 68.2 0.3 1.2e-18 67.5 0.3 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 GAN03474.1 - 6.4e-08 32.5 0.1 1.2e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain RNA_ligase PF09414.10 GAN03474.1 - 1.5e-06 28.6 0.4 2.4e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_N PF04675.14 GAN03474.1 - 0.0025 18.2 0.0 0.015 15.6 0.0 2.1 1 1 0 1 1 1 1 DNA ligase N terminus mRNA_cap_enzyme PF01331.19 GAN03474.1 - 0.0075 16.1 0.7 0.048 13.5 0.7 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain TMEM252 PF15664.5 GAN03474.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family Methyltransf_11 PF08241.12 GAN03475.1 - 3.1e-14 53.4 0.0 6.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN03475.1 - 1.1e-12 48.5 0.1 4e-12 46.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN03475.1 - 1.9e-12 47.2 0.0 2.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN03475.1 - 9.2e-07 29.5 0.0 1.8e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 GAN03475.1 - 7.9e-05 22.4 0.0 0.00021 21.0 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 GAN03475.1 - 0.00012 21.5 0.1 0.33 10.2 0.1 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family TPMT PF05724.11 GAN03475.1 - 0.0024 17.5 0.0 0.0045 16.7 0.0 1.5 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 GAN03475.1 - 0.023 14.3 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 GAN03475.1 - 0.036 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAN03475.1 - 0.054 13.3 0.0 0.21 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain THUMP PF02926.17 GAN03476.1 - 6.8e-16 58.7 0.1 1.6e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 THUMP domain Ribosomal_60s PF00428.19 GAN03476.1 - 0.0086 16.6 0.9 0.032 14.8 0.9 2.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SKG6 PF08693.10 GAN03477.1 - 0.054 12.9 4.0 0.15 11.5 4.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 GAN03477.1 - 0.074 13.9 0.0 0.17 12.8 0.0 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 GAN03479.1 - 3.4e-64 216.8 0.0 5.1e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03479.1 - 8.3e-51 172.8 0.0 1.5e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN03479.1 - 2.5e-05 23.7 0.0 0.096 12.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_2 PF07647.17 GAN03479.1 - 3.4e-05 23.9 0.0 9.2e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN03479.1 - 0.001 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 GAN03479.1 - 0.0015 18.8 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Pkinase_fungal PF17667.1 GAN03479.1 - 0.0043 15.9 1.8 0.0095 14.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAN03479.1 - 0.016 14.6 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.17 GAN03480.1 - 4e-69 232.0 0.4 4.5e-69 231.8 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family PROCT PF08084.11 GAN03481.1 - 0.11 12.4 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 PROCT (NUC072) domain DPBB_1 PF03330.18 GAN03482.1 - 7.5e-11 42.2 0.1 1.2e-10 41.5 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN03482.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 Barwin family DUF2647 PF10839.8 GAN03482.1 - 0.061 13.4 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) Ras PF00071.22 GAN03483.1 - 2.1e-31 108.7 0.2 2.5e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN03483.1 - 4.2e-24 85.1 0.0 7e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN03483.1 - 3.5e-07 29.8 0.1 4.5e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN03483.1 - 0.00011 21.6 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 GAN03483.1 - 0.006 15.5 0.9 1.1 8.0 0.1 2.3 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 GAN03483.1 - 0.049 13.2 0.4 1.6 8.2 0.4 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TniB PF05621.11 GAN03483.1 - 0.055 12.9 0.1 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein ATP-synt_ab PF00006.25 GAN03483.1 - 0.084 12.5 0.2 4.9 6.7 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sporozoite_P67 PF05642.11 GAN03483.1 - 7.6 4.5 8.5 11 3.9 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HlyIII PF03006.20 GAN03484.1 - 1.7e-58 198.0 22.8 2.2e-58 197.7 22.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DNA_pol_A_exo1 PF01612.20 GAN03485.1 - 2e-17 63.4 0.0 8.8e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease IBR PF01485.21 GAN03485.1 - 1.5e-12 47.5 42.6 3.8e-10 39.9 8.4 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 GAN03485.1 - 0.00043 20.1 7.6 0.00043 20.1 7.6 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN03485.1 - 0.0011 19.3 10.1 0.0011 19.3 10.1 4.5 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 GAN03485.1 - 0.0018 18.2 7.0 0.0018 18.2 7.0 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAN03485.1 - 0.016 15.1 7.0 0.016 15.1 7.0 4.3 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) EF-1_beta_acid PF10587.9 GAN03485.1 - 1.5 9.3 8.1 6.6 7.3 8.1 2.2 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region TMP-TENI PF02581.17 GAN03485.1 - 3.8 6.8 4.4 74 2.6 0.1 3.6 3 1 1 4 4 4 0 Thiamine monophosphate synthase CHCH PF06747.13 GAN03486.1 - 6.6e-09 35.7 5.4 9.2e-09 35.2 5.4 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 GAN03486.1 - 0.0057 16.4 0.5 0.0073 16.0 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 GAN03486.1 - 0.0084 16.4 4.4 0.056 13.8 4.5 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GAN03486.1 - 0.017 15.2 1.7 0.028 14.4 1.7 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 GAN03486.1 - 0.025 14.9 2.4 0.58 10.6 0.3 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Meis_PKNOX_N PF16493.5 GAN03486.1 - 0.07 13.5 3.1 2.5 8.5 0.3 2.3 1 1 1 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 CX9C PF16860.5 GAN03486.1 - 0.11 12.5 3.7 0.48 10.5 3.8 1.9 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, adh_short PF00106.25 GAN03487.1 - 1.4e-40 138.8 0.0 2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN03487.1 - 1.9e-24 86.5 0.0 2.6e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN03487.1 - 6.5e-14 52.2 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN03487.1 - 8.9e-05 22.1 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAN03487.1 - 0.00014 21.4 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAN03487.1 - 0.0018 17.3 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAN03487.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 GAN03487.1 - 0.0092 15.3 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 GAN03487.1 - 0.011 14.9 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 GAN03487.1 - 0.015 15.7 0.2 0.028 14.9 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 GAN03487.1 - 0.018 15.0 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 GAN03487.1 - 0.045 14.3 0.1 0.14 12.7 0.0 1.9 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 GAN03487.1 - 0.052 13.6 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 GAN03487.1 - 0.11 12.4 0.2 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGP_phosphatase PF09419.10 GAN03488.1 - 6.7e-47 159.2 0.0 7.9e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 GAN03488.1 - 9.1e-06 25.7 0.0 2e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAN03488.1 - 0.0066 16.8 0.0 1.5 9.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase SR-25 PF10500.9 GAN03489.1 - 0.0023 17.6 12.6 0.0035 17.0 12.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Metallophos PF00149.28 GAN03490.1 - 7.4e-38 131.1 0.1 1.3e-37 130.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN03490.1 - 1e-16 61.1 0.0 2.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF2015 PF09435.10 GAN03491.1 - 0.054 13.3 1.0 0.51 10.2 0.6 2.1 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2015) TPPII_N PF12583.8 GAN03491.1 - 0.084 13.4 2.7 0.14 12.7 2.7 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal FAM220 PF15487.6 GAN03491.1 - 0.22 11.1 2.9 0.29 10.7 2.9 1.1 1 0 0 1 1 1 0 FAM220 family GRAM PF02893.20 GAN03492.1 - 1e-29 102.7 8.7 1.1e-19 70.4 1.7 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 GAN03492.1 - 5.5e-28 97.7 0.0 2e-27 96.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 GAN03492.1 - 2.1e-11 44.2 1.5 7.1e-11 42.6 0.2 2.5 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 GAN03492.1 - 2.9e-07 29.7 0.0 5.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 GAN03492.1 - 0.00081 19.6 2.1 0.0012 19.1 0.5 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 GAN03492.1 - 0.28 11.6 1.1 6.8 7.2 1.1 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain NOA36 PF06524.12 GAN03492.1 - 2.5 7.3 5.9 6 6.1 5.9 1.6 1 0 0 1 1 1 0 NOA36 protein ECR1_N PF14382.6 GAN03493.1 - 1.4e-15 56.8 2.0 2.8e-15 55.8 2.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 GAN03493.1 - 1.1e-11 44.9 0.1 3.9e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 KH domain EXOSC1 PF10447.9 GAN03493.1 - 0.15 12.7 0.2 3.2 8.4 0.1 2.3 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 tRNA-synt_2c PF01411.19 GAN03494.1 - 2.3e-209 696.5 0.0 3.1e-209 696.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAN03494.1 - 1.1e-18 67.0 0.4 2.8e-18 65.7 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAN03494.1 - 3.1e-17 63.3 5.3 1e-16 61.6 5.3 1.9 1 0 0 1 1 1 1 DHHA1 domain LBP_C PF17386.2 GAN03495.1 - 0.01 15.7 0.2 0.028 14.3 0.1 1.8 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain HLH PF00010.26 GAN03496.1 - 5.2e-17 61.5 0.6 1.2e-16 60.4 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 GAN03496.1 - 0.18 10.1 10.2 0.27 9.5 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAN03496.1 - 0.27 9.3 5.1 0.41 8.7 5.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi SURF6 PF04935.12 GAN03496.1 - 0.44 10.3 14.4 0.65 9.8 10.7 2.1 2 0 0 2 2 2 0 Surfeit locus protein 6 Ecl1 PF12855.7 GAN03497.1 - 8.8e-11 43.3 0.9 8.8e-11 43.3 0.9 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 GAN03497.1 - 0.0059 16.7 0.4 0.0059 16.7 0.4 1.6 2 0 0 2 2 2 1 MYND finger SET PF00856.28 GAN03498.1 - 3.1e-10 40.7 0.1 1.6e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAN03498.1 - 0.0024 18.5 0.0 0.0051 17.5 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Apt1 PF10351.9 GAN03499.1 - 5.8e-128 427.7 9.0 5.8e-128 427.7 9.0 2.6 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 GAN03499.1 - 2.3e-115 386.2 8.4 8.1e-115 384.4 8.4 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 GAN03499.1 - 1.2e-39 135.9 0.0 4.5e-39 134.1 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 GAN03499.1 - 2.1e-37 128.4 0.1 1e-36 126.2 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 GAN03499.1 - 9e-28 97.0 4.5 1.1e-27 96.7 0.3 3.6 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain RNase_E_G PF10150.9 GAN03500.1 - 0.0015 18.0 0.4 0.0015 18.0 0.4 1.8 2 0 0 2 2 2 1 Ribonuclease E/G family DUF3699 PF12480.8 GAN03500.1 - 0.041 14.0 0.4 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) DUF573 PF04504.14 GAN03500.1 - 0.17 12.5 5.5 26 5.6 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF573 MTS PF05175.14 GAN03501.1 - 5.1e-15 55.4 0.0 8.2e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAN03501.1 - 2.8e-11 43.5 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN03501.1 - 8.2e-09 36.1 0.0 1.5e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 GAN03501.1 - 6.5e-07 28.9 0.0 9.7e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.13 GAN03501.1 - 1.7e-06 27.7 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 GAN03501.1 - 9.3e-05 22.2 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 GAN03501.1 - 0.00025 20.5 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 GAN03501.1 - 0.00041 20.3 0.3 0.00098 19.1 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN03501.1 - 0.00048 20.8 0.0 0.00099 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 GAN03501.1 - 0.00053 19.4 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_16 PF10294.9 GAN03501.1 - 0.00054 19.8 0.1 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_32 PF13679.6 GAN03501.1 - 0.00067 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 GAN03501.1 - 0.00077 19.0 0.1 0.002 17.7 0.1 1.6 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_23 PF13489.6 GAN03501.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN03501.1 - 0.0019 18.8 0.0 0.0046 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 GAN03501.1 - 0.0045 17.5 0.1 0.0092 16.5 0.1 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Cons_hypoth95 PF03602.15 GAN03501.1 - 0.0051 16.5 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_20 PF12147.8 GAN03501.1 - 0.028 13.6 0.0 0.075 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.10 GAN03501.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF938 PF06080.12 GAN03501.1 - 0.054 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 GAN03501.1 - 0.062 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 GAN03501.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) TRM PF02005.16 GAN03501.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 GAN03501.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein KH_1 PF00013.29 GAN03502.1 - 7e-52 173.1 7.3 5.9e-18 64.5 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAN03502.1 - 7.2e-13 48.2 2.6 0.002 17.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAN03502.1 - 3.9e-09 36.3 3.7 0.0022 17.8 0.0 3.7 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 GAN03502.1 - 1e-05 25.4 0.0 1.2 9.2 0.0 3.2 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 GAN03502.1 - 0.0058 16.7 1.2 3.4 7.8 0.0 3.3 3 0 0 3 3 3 1 NusA-like KH domain FHA_2 PF17913.1 GAN03502.1 - 0.027 14.7 0.1 10 6.5 0.0 2.4 2 0 0 2 2 2 0 FHA domain GRP PF07172.11 GAN03502.1 - 0.028 15.1 6.9 0.028 15.1 6.9 6.4 5 2 1 6 6 6 0 Glycine rich protein family Mito_carr PF00153.27 GAN03503.1 - 2.3e-65 216.6 1.0 6.6e-23 80.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PFK PF00365.20 GAN03504.1 - 6.5e-193 639.3 2.6 1.5e-107 359.2 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 GAN03504.1 - 0.02 15.3 0.1 0.044 14.2 0.1 1.6 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 GAN03504.1 - 0.068 12.8 0.6 0.38 10.4 0.1 2.5 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Acetyltransf_1 PF00583.25 GAN03505.1 - 8.2e-09 35.7 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN03505.1 - 2.9e-07 30.5 0.0 4.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN03505.1 - 4e-07 30.4 0.1 8.6e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAN03505.1 - 0.00027 21.6 0.0 0.00044 20.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAN03505.1 - 0.0028 17.8 0.0 0.0061 16.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 GAN03505.1 - 0.0032 16.9 0.2 0.0058 16.1 0.2 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase DUF624 PF04854.14 GAN03505.1 - 0.053 13.6 1.0 0.18 11.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Acetyltransf_1 PF00583.25 GAN03506.1 - 1.7e-09 37.9 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN03506.1 - 2.6e-09 37.1 0.0 3.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN03506.1 - 4.4e-09 36.6 0.0 7.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAN03506.1 - 0.00039 20.5 0.0 0.0026 17.8 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN03506.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAN03506.1 - 0.0093 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 GAN03506.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 GAN03506.1 - 0.06 13.5 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thi4 PF01946.17 GAN03507.1 - 1.8e-109 364.5 0.3 2.2e-109 364.2 0.3 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAN03507.1 - 7.8e-10 38.8 0.1 6.1e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAN03507.1 - 2.5e-07 30.1 0.8 0.00025 20.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAN03507.1 - 1.1e-06 28.1 0.1 1.5e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN03507.1 - 4e-06 27.0 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAN03507.1 - 5.9e-05 22.3 0.1 0.00012 21.3 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAN03507.1 - 0.0002 21.4 0.1 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 GAN03507.1 - 0.00031 20.0 0.0 0.32 10.0 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAN03507.1 - 0.00032 20.2 0.4 0.00058 19.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 GAN03507.1 - 0.0046 16.4 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase HI0933_like PF03486.14 GAN03507.1 - 0.0075 15.0 0.0 0.0075 15.0 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAN03507.1 - 0.018 14.3 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GSIII_N PF12437.8 GAN03508.1 - 3.1e-65 218.7 0.1 5.6e-65 217.9 0.1 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 GAN03508.1 - 3.8e-38 130.0 0.1 7.1e-38 129.1 0.1 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 GAN03508.1 - 2.6e-20 72.7 0.0 4.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain FR47 PF08445.10 GAN03509.1 - 6.4e-09 35.7 0.0 5.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 GAN03509.1 - 9.8e-05 22.6 0.0 0.00023 21.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN03509.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ApbA PF02558.16 GAN03510.1 - 2.5e-30 105.1 0.0 3.6e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAN03510.1 - 4.3e-27 94.8 0.1 7e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.23 GAN03510.1 - 0.00025 21.1 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 GAN03510.1 - 0.0024 18.4 0.0 0.0096 16.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 GAN03510.1 - 0.029 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GIDA PF01134.22 GAN03510.1 - 0.072 12.2 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 GAN03510.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 GAN03510.1 - 0.11 11.8 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bestrophin PF01062.21 GAN03511.1 - 2.4e-53 181.5 0.2 1.7e-27 96.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4239 PF14023.6 GAN03511.1 - 0.027 14.2 4.2 0.15 11.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) HBD PF18534.1 GAN03511.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Helical bundle domain zf-CCHC PF00098.23 GAN03512.1 - 0.0017 18.4 38.0 0.012 15.7 5.4 4.4 4 0 0 4 4 4 4 Zinc knuckle Upf2 PF04050.14 GAN03512.1 - 0.16 12.7 0.3 0.16 12.7 0.3 3.8 3 2 0 3 3 3 0 Up-frameshift suppressor 2 Nup88 PF10168.9 GAN03513.1 - 1.9e-31 108.6 19.9 1.7e-16 59.2 0.2 3.1 3 0 0 3 3 3 3 Nuclear pore component DUF4407 PF14362.6 GAN03513.1 - 0.0022 17.4 7.4 0.0039 16.6 7.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF3584 PF12128.8 GAN03513.1 - 0.07 10.6 11.7 0.11 10.0 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 GAN03513.1 - 0.19 11.7 2.6 1.6 8.8 2.5 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54 PF13874.6 GAN03513.1 - 0.47 10.6 10.2 0.2 11.8 5.7 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 FliD_C PF07195.12 GAN03513.1 - 0.52 9.7 6.1 0.072 12.5 0.9 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus FUSC PF04632.12 GAN03513.1 - 0.58 8.6 2.7 0.84 8.1 2.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prominin PF05478.11 GAN03513.1 - 1.1 7.2 6.8 1.9 6.3 6.8 1.4 1 0 0 1 1 1 0 Prominin DUF883 PF05957.13 GAN03513.1 - 1.9 9.1 5.2 0.65 10.6 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.11 GAN03513.1 - 2.1 7.2 15.0 7.8 5.3 14.8 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 GAN03513.1 - 2.1 7.5 8.2 4.4 6.5 8.2 1.6 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 GAN03513.1 - 4.1 6.9 10.9 8.9 5.8 10.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 GAN03513.1 - 4.8 7.3 8.0 4.5 7.3 3.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 GAN03513.1 - 5.5 7.3 13.7 9.9 6.5 12.4 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 GAN03513.1 - 8.1 7.0 9.5 3.8 8.0 1.7 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Syja_N PF02383.18 GAN03515.1 - 3.5e-85 286.1 0.3 4.5e-85 285.8 0.3 1.1 1 0 0 1 1 1 1 SacI homology domain Syja_N PF02383.18 GAN03516.1 - 2.3e-81 273.6 0.1 2.3e-81 273.6 0.1 1.9 2 0 0 2 2 2 1 SacI homology domain Crystall PF00030.19 GAN03516.1 - 0.031 14.5 1.1 2.3 8.5 0.2 2.8 2 0 0 2 2 2 0 Beta/Gamma crystallin Ins_allergen_rp PF06757.13 GAN03516.1 - 0.14 12.1 0.8 1.5 8.7 0.2 2.6 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification 14-3-3 PF00244.20 GAN03517.1 - 6.8e-106 352.7 3.0 7.9e-106 352.5 3.0 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 GAN03517.1 - 0.032 14.2 0.2 0.079 13.0 0.2 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Ribosomal_S9 PF00380.19 GAN03518.1 - 1.2e-31 109.8 0.1 1.3e-31 109.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 LRR_6 PF13516.6 GAN03519.1 - 0.00088 19.1 1.2 0.17 12.0 0.1 3.4 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.6 GAN03519.1 - 0.0012 18.6 0.6 1.4 8.7 0.0 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAN03519.1 - 0.0019 18.6 8.1 0.13 12.7 0.8 3.7 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) OPT PF03169.15 GAN03520.1 - 1.1e-129 433.9 10.6 1.6e-83 281.4 2.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein LRR19-TM PF15176.6 GAN03520.1 - 0.25 11.4 3.0 0.4 10.7 0.2 2.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Radical_SAM_C PF16199.5 GAN03522.1 - 8.2e-33 112.3 0.1 2.1e-32 111.0 0.1 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 GAN03522.1 - 3.5e-18 66.5 0.0 9.4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 GAN03522.1 - 3.5e-09 36.9 0.0 7.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN03522.1 - 9.3e-06 25.6 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN03522.1 - 0.024 15.1 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_1 PF00175.21 GAN03523.1 - 1.1e-31 109.7 0.0 1.7e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAN03523.1 - 5.5e-21 74.8 0.0 1.9e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAN03523.1 - 7e-08 32.7 0.0 6.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAN03523.1 - 0.02 15.1 0.0 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain TFR_dimer PF04253.15 GAN03524.1 - 6.2e-27 94.1 0.1 1.3e-26 93.1 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAN03524.1 - 2.2e-21 76.5 0.0 5.6e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAN03524.1 - 3.7e-10 39.7 0.0 8.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAN03524.1 - 0.0035 17.1 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.22 GAN03525.1 - 3.9e-05 23.6 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PA domain Marek_A PF02124.15 GAN03525.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF3357 PF11837.8 GAN03525.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Sigma_reg_N PF13800.6 GAN03525.1 - 0.16 12.3 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Peptidase_M28 PF04389.17 GAN03526.1 - 1.9e-06 27.7 0.0 2.9e-05 23.9 0.0 2.1 1 1 1 2 2 2 1 Peptidase family M28 PA PF02225.22 GAN03526.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 PA domain Sigma_reg_N PF13800.6 GAN03527.1 - 0.013 15.8 0.2 0.019 15.2 0.2 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Marek_A PF02124.15 GAN03527.1 - 0.039 13.8 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Marek's disease glycoprotein A Y_phosphatase PF00102.27 GAN03529.1 - 6.5e-67 225.5 1.6 9e-66 221.8 0.6 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAN03529.1 - 0.0085 16.1 0.0 0.028 14.4 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 GAN03529.1 - 0.15 11.9 0.1 0.45 10.3 0.1 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Lipase_3 PF01764.25 GAN03531.1 - 3.7e-31 107.9 0.0 6.5e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAN03531.1 - 0.0084 15.7 0.1 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 GAN03531.1 - 0.061 13.9 0.0 0.2 12.2 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN03531.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Hydrolase PF00702.26 GAN03532.1 - 4.5e-09 36.9 0.0 9.9e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN03532.1 - 8.1e-09 35.8 0.0 1.2e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN03532.1 - 4.7e-05 23.4 0.1 0.00016 21.7 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.7 GAN03532.1 - 0.042 13.7 0.1 0.09 12.6 0.0 1.6 2 0 0 2 2 2 0 Acid Phosphatase Peptidase_M15 PF01427.17 GAN03533.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase F-box-like PF12937.7 GAN03534.1 - 9.1e-09 35.1 0.2 1.9e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03534.1 - 0.0044 16.9 0.1 0.0097 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain Fe-S_biosyn PF01521.20 GAN03535.1 - 3.8e-18 65.7 0.2 5.1e-18 65.3 0.2 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Mito_carr PF00153.27 GAN03536.1 - 3.1e-68 225.8 2.9 7.5e-25 86.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ACAS_N PF16177.5 GAN03536.1 - 0.022 14.7 1.6 0.046 13.7 1.6 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus GATA PF00320.27 GAN03537.1 - 6.4e-13 48.1 5.5 6.4e-13 48.1 5.5 2.0 2 0 0 2 2 2 1 GATA zinc finger LtrA PF06772.11 GAN03539.1 - 2.9e-08 33.3 10.7 3.7e-08 33.0 10.7 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Ldh_1_C PF02866.18 GAN03540.1 - 3.1e-49 167.1 0.0 6.5e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAN03540.1 - 7.8e-46 155.7 0.5 1.4e-45 154.8 0.5 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain LtrA PF06772.11 GAN03540.1 - 3.6e-19 69.2 19.1 8.3e-19 68.0 13.1 2.4 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) 3Beta_HSD PF01073.19 GAN03540.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 GAN03540.1 - 0.058 13.5 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF5632 PF18646.1 GAN03540.1 - 0.11 12.5 0.0 16 5.7 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5632) Glyco_hydro_4 PF02056.16 GAN03540.1 - 0.15 11.6 2.0 3 7.4 0.0 2.7 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 GAN03540.1 - 0.72 9.1 3.3 0.93 8.8 0.2 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pex14_N PF04695.13 GAN03540.1 - 1.2 9.8 5.8 2.2 8.9 5.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.9 GAN03540.1 - 4.3 6.4 9.2 6.2 5.9 9.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 GAN03541.1 - 2.3e-41 141.9 0.4 1.4e-21 77.0 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03541.1 - 1.2e-10 41.2 0.5 5.6e-06 25.8 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN03541.1 - 7.7 5.2 9.9 0.48 9.1 3.4 2.2 1 1 1 2 2 2 0 Fungal protein kinase CENP-B_dimeris PF09026.10 GAN03542.1 - 7.4 7.0 22.3 6.2 7.3 6.8 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Aa_trans PF01490.18 GAN03543.1 - 1.4e-60 205.2 29.5 1.8e-60 204.8 29.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 GAN03543.1 - 1.3e-05 24.3 39.8 0.00028 19.8 39.8 2.2 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 GAN03543.1 - 4e-05 22.6 13.4 4e-05 22.6 13.4 3.0 1 1 1 3 3 3 1 Spore germination protein zinc-ribbons_6 PF07191.12 GAN03544.1 - 0.023 14.6 10.7 0.04 13.9 1.2 2.2 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_12 PF11331.8 GAN03544.1 - 0.81 9.5 0.0 0.81 9.5 0.0 2.7 3 1 0 3 3 3 0 Probable zinc-ribbon domain DZR PF12773.7 GAN03544.1 - 1.7 8.7 14.0 10 6.2 14.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon AAA PF00004.29 GAN03546.1 - 9.1e-10 39.1 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAN03546.1 - 0.00041 20.3 0.2 0.93 9.4 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_22 PF13401.6 GAN03546.1 - 0.0013 19.1 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAN03546.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAN03546.1 - 0.0077 16.3 0.0 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAN03546.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Vault_2 PF17794.1 GAN03546.1 - 0.064 13.7 0.1 6.6 7.2 0.0 3.0 2 0 0 2 2 2 0 Major Vault Protein repeat domain AAA_assoc_2 PF16193.5 GAN03546.1 - 0.071 13.4 0.0 0.31 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA C-terminal domain AAA_30 PF13604.6 GAN03546.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAN03546.1 - 0.15 12.6 0.8 0.45 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAN03546.1 - 0.64 10.4 0.0 0.64 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain WLM PF08325.10 GAN03547.1 - 2.3e-56 190.9 0.0 3.2e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 GAN03547.1 - 2.4e-09 36.4 13.5 2.6e-05 23.4 6.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 GAN03547.1 - 0.012 15.7 0.2 0.023 14.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 SprT-like PF10263.9 GAN03547.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 SprT-like family zf-4CXXC_R1 PF10497.9 GAN03547.1 - 0.089 13.0 10.9 0.14 12.4 2.7 3.0 3 1 1 4 4 4 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DZR PF12773.7 GAN03547.1 - 0.32 11.1 8.8 0.66 10.0 8.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon Sulfate_transp PF00916.20 GAN03548.1 - 1.8e-59 201.4 18.4 2.7e-59 200.8 18.4 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 GAN03548.1 - 2.1e-14 53.4 0.0 3.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 GAN03548.1 - 1.4e-10 40.8 0.0 2.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain Rer1 PF03248.13 GAN03548.1 - 8.4 6.1 10.4 0.59 9.8 0.0 3.3 3 0 0 3 3 3 0 Rer1 family DUF1010 PF06231.11 GAN03549.1 - 0.074 13.6 1.0 0.13 12.8 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1010) SpoIIE PF07228.12 GAN03550.1 - 2.5e-11 43.9 0.0 1.6e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Mur_ligase_M PF08245.12 GAN03550.1 - 2.3e-10 40.8 0.0 7.6e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain PP2C_2 PF13672.6 GAN03550.1 - 4.1e-08 33.1 0.1 7.2e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 GAN03550.1 - 6.5e-08 32.5 0.2 0.0037 16.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Mur_ligase_C PF02875.21 GAN03550.1 - 0.00015 21.9 0.0 0.00037 20.7 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DNA_primase_S PF01896.19 GAN03551.1 - 3.1e-58 196.7 1.7 5.1e-58 196.0 1.7 1.4 1 0 0 1 1 1 1 DNA primase small subunit 4HBT_2 PF13279.6 GAN03551.1 - 0.078 13.5 0.5 0.76 10.3 0.5 2.3 1 1 0 1 1 1 0 Thioesterase-like superfamily DUF647 PF04884.14 GAN03552.1 - 4.7e-54 183.6 0.2 6.1e-54 183.2 0.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis ABC_tran PF00005.27 GAN03554.1 - 9.5e-35 120.1 1.3 1.9e-18 67.3 0.1 4.6 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAN03554.1 - 2.9e-12 47.0 0.1 0.0044 16.9 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN03554.1 - 1.2e-09 38.0 0.0 0.11 11.9 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 GAN03554.1 - 7.5e-08 32.8 0.0 0.022 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAN03554.1 - 2.5e-07 30.8 0.0 0.001 19.0 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAN03554.1 - 5.4e-07 30.0 0.2 0.28 11.4 0.0 4.5 6 0 0 6 6 3 2 AAA domain AAA_29 PF13555.6 GAN03554.1 - 8.7e-07 28.6 0.1 0.026 14.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAN03554.1 - 1.3e-06 28.9 0.0 0.075 13.5 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAN03554.1 - 1.5e-06 28.3 0.0 0.0054 16.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 GAN03554.1 - 9.6e-06 26.2 0.1 0.032 14.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 GAN03554.1 - 1.7e-05 24.0 0.1 0.056 12.4 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAN03554.1 - 2.7e-05 24.6 0.1 0.04 14.3 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain RNA_helicase PF00910.22 GAN03554.1 - 2.9e-05 24.4 0.5 0.63 10.5 0.0 3.3 4 0 0 4 4 2 2 RNA helicase NACHT PF05729.12 GAN03554.1 - 6.6e-05 22.9 0.0 0.19 11.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Chromo PF00385.24 GAN03554.1 - 8.9e-05 22.3 1.4 0.00038 20.3 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 GAN03554.1 - 0.00015 21.6 1.9 0.36 10.5 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 GAN03554.1 - 0.00015 22.3 10.5 0.038 14.5 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAN03554.1 - 0.00035 20.4 0.0 0.67 9.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 GAN03554.1 - 0.0004 19.6 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 GAN03554.1 - 0.00057 19.7 0.0 0.47 10.2 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 GAN03554.1 - 0.0015 18.5 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain CLP1_P PF16575.5 GAN03554.1 - 0.0024 17.7 0.0 0.25 11.1 0.0 2.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 GAN03554.1 - 0.0025 18.0 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain 4HB PF17947.1 GAN03554.1 - 0.0043 17.1 0.3 0.028 14.5 0.1 2.5 2 0 0 2 2 1 1 Four helical bundle domain IstB_IS21 PF01695.17 GAN03554.1 - 0.0045 16.8 0.0 4 7.1 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAN03554.1 - 0.0062 16.6 0.0 4 7.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 GAN03554.1 - 0.01 15.4 0.0 6.4 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAN03554.1 - 0.013 15.2 0.0 0.85 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GAN03554.1 - 0.016 14.8 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 GAN03554.1 - 0.025 14.5 0.1 6.4 6.6 0.0 3.3 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 GAN03554.1 - 0.025 14.1 0.0 4.1 6.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAN03554.1 - 0.027 13.7 0.1 2.2 7.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 GAN03554.1 - 0.029 14.1 0.0 1.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 GAN03554.1 - 0.035 14.1 0.4 1.4 8.9 0.0 2.9 3 0 0 3 3 2 0 Dynamin family Zeta_toxin PF06414.12 GAN03554.1 - 0.039 13.2 0.1 11 5.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DRIM PF07539.12 GAN03554.1 - 0.039 12.3 0.0 0.12 10.6 0.0 1.8 1 1 0 1 1 1 0 Down-regulated in metastasis NTPase_1 PF03266.15 GAN03554.1 - 0.057 13.3 0.1 4.7 7.1 0.1 2.7 2 0 0 2 2 2 0 NTPase PRK PF00485.18 GAN03554.1 - 0.057 13.1 0.2 4.7 6.9 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 GAN03554.1 - 0.095 12.7 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 GAN03554.1 - 0.12 12.5 6.1 0.91 9.6 0.0 3.4 4 0 0 4 4 2 0 Helicase HerA, central domain AAA_17 PF13207.6 GAN03554.1 - 0.41 11.1 2.9 34 4.8 0.1 3.8 3 0 0 3 3 3 0 AAA domain HEAT PF02985.22 GAN03554.1 - 0.93 9.9 2.9 1.2e+02 3.3 0.0 4.6 5 0 0 5 5 3 0 HEAT repeat AAA_13 PF13166.6 GAN03554.1 - 1.8 7.1 6.9 11 4.5 0.0 3.6 5 0 0 5 5 3 0 AAA domain BLOC1_2 PF10046.9 GAN03555.1 - 0.018 15.3 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CAP PF00188.26 GAN03556.1 - 2.4e-22 80.1 8.4 1e-21 78.1 8.4 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DnaJ PF00226.31 GAN03557.1 - 3.2e-22 78.4 2.6 3.2e-22 78.4 2.6 3.1 4 0 0 4 4 3 1 DnaJ domain TPR_2 PF07719.17 GAN03557.1 - 7.8e-21 72.5 9.5 0.017 15.2 0.1 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAN03557.1 - 2.1e-19 68.4 12.9 0.0013 18.4 0.2 7.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAN03557.1 - 3.5e-18 66.0 0.7 8.1e-05 23.2 0.1 4.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAN03557.1 - 2e-17 63.1 0.2 0.0013 18.8 0.0 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAN03557.1 - 1.8e-16 60.4 6.7 2.1e-05 25.0 0.0 5.2 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN03557.1 - 9.9e-14 50.9 1.7 0.0036 18.0 0.1 6.2 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAN03557.1 - 2e-12 46.6 5.6 0.0012 19.0 0.8 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN03557.1 - 1.2e-11 44.0 16.6 4.4e-05 23.1 0.6 6.4 5 2 3 8 8 8 3 TPR repeat TPR_8 PF13181.6 GAN03557.1 - 3.4e-11 42.4 14.7 0.013 15.7 0.0 7.6 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN03557.1 - 8.5e-11 41.9 10.2 0.0016 18.7 0.0 4.4 4 2 0 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAN03557.1 - 5.6e-08 32.9 4.4 0.93 10.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAN03557.1 - 4e-05 23.9 4.8 0.038 14.3 0.1 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN03557.1 - 0.00018 21.3 4.3 1.2 9.3 0.0 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN03557.1 - 0.0054 17.0 11.5 2.6 8.4 0.2 5.3 4 3 1 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAN03557.1 - 0.013 15.9 2.9 0.028 14.9 0.1 2.9 3 1 2 5 5 4 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 GAN03557.1 - 0.016 15.3 2.2 3.7 7.7 0.1 4.4 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat CotJB PF12652.7 GAN03557.1 - 0.02 15.1 2.9 0.056 13.7 0.0 3.0 3 0 0 3 3 2 0 CotJB protein COMMD1_N PF17221.3 GAN03557.1 - 0.023 15.0 0.0 0.087 13.1 0.0 2.0 1 0 0 1 1 1 0 COMMD1 N-terminal domain DUF4398 PF14346.6 GAN03557.1 - 0.07 13.8 7.1 0.25 12.0 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) HrpB1_HrpK PF09613.10 GAN03557.1 - 0.1 12.2 0.1 14 5.4 0.0 2.7 2 1 1 3 3 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Sod_Ni PF09055.11 GAN03557.1 - 0.11 13.0 2.3 3.7 8.1 0.1 2.7 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase DUF357 PF04010.13 GAN03557.1 - 0.13 12.4 0.9 1.7 8.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF357) YqaH PF17448.2 GAN03557.1 - 0.16 12.3 0.3 0.71 10.2 0.0 2.4 2 0 0 2 2 1 0 Uncharacterized YqaH-like TPR_10 PF13374.6 GAN03557.1 - 0.23 11.4 4.8 3.2 7.7 0.1 4.4 6 0 0 6 6 4 0 Tetratricopeptide repeat SPT16 PF08644.11 GAN03557.1 - 0.51 10.5 7.0 0.22 11.7 0.3 2.9 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) zf-RVT PF13966.6 GAN03558.1 - 2.5e-06 28.1 1.3 5.2e-06 27.1 1.3 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Sugar_tr PF00083.24 GAN03559.1 - 2.1e-118 396.1 21.1 2.4e-118 395.9 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN03559.1 - 5.9e-17 61.6 40.6 8.2e-13 48.0 11.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily CCER1 PF15482.6 GAN03559.1 - 0.17 11.8 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 DUF3487 PF11990.8 GAN03559.1 - 6.4 6.7 6.6 1.6 8.7 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) PA26 PF04636.13 GAN03560.1 - 1.6e-87 294.3 0.0 2.5e-87 293.7 0.0 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Big_7 PF17957.1 GAN03561.1 - 0.047 14.5 3.3 0.36 11.6 2.1 2.5 2 1 0 2 2 2 0 Bacterial Ig domain CTP_transf_like PF01467.26 GAN03563.1 - 3.5e-29 101.9 0.0 4.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like UQ_con PF00179.26 GAN03564.1 - 4.3e-14 52.3 0.0 4.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN03564.1 - 0.15 12.3 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain VASt PF16016.5 GAN03565.1 - 2.2e-43 148.3 0.3 4.6e-43 147.3 0.3 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAN03565.1 - 2.2e-24 85.5 0.0 5.4e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 GRAM domain MMADHC PF10229.9 GAN03565.1 - 2e-23 83.5 0.0 2e-23 83.5 0.0 2.0 2 0 0 2 2 2 1 Methylmalonic aciduria and homocystinuria type D protein NDUF_C2 PF06374.11 GAN03565.1 - 0.0075 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Fib_alpha PF08702.10 GAN03565.1 - 2.1 8.5 7.1 0.32 11.2 1.6 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ER-remodelling PF14755.6 GAN03565.1 - 7.3 6.9 16.8 2.4 8.4 5.8 2.7 2 0 0 2 2 2 0 Intracellular membrane remodeller Nup192 PF11894.8 GAN03566.1 - 5.8e-202 673.5 30.7 9e-202 672.9 30.7 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 SUIM_assoc PF16619.5 GAN03566.1 - 0.069 13.2 6.3 0.22 11.6 6.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SUB1_ProdP9 PF18213.1 GAN03566.1 - 0.14 12.1 0.4 21 5.1 0.0 3.3 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 TFIIA PF03153.13 GAN03566.1 - 0.9 9.5 8.2 0.041 13.9 2.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S6e PF01092.19 GAN03567.1 - 2.3e-35 121.3 3.2 1.2e-18 67.3 0.0 2.9 2 1 1 3 3 3 2 Ribosomal protein S6e Arm-DNA-bind_4 PF14657.6 GAN03567.1 - 7.3 6.4 8.3 26 4.7 0.4 3.4 3 0 0 3 3 3 0 Arm DNA-binding domain IF4E PF01652.18 GAN03568.1 - 1.6e-55 187.3 0.8 1.9e-55 187.0 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PSP PF04046.16 GAN03568.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 PSP Ribosomal_S7e PF01251.18 GAN03569.1 - 2.3e-81 272.0 0.7 2.6e-81 271.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.22 GAN03570.1 - 7.3e-60 201.2 0.0 8.7e-60 201.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN03570.1 - 1.4e-22 80.2 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN03570.1 - 4.8e-08 32.7 0.0 5.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN03570.1 - 8.6e-05 22.1 0.1 0.00024 20.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN03570.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN03570.1 - 0.0026 17.7 0.0 0.84 9.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase 2Fe-2S_thioredx PF01257.19 GAN03570.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin IstB_IS21 PF01695.17 GAN03570.1 - 0.11 12.2 0.6 1.2 8.9 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein PRAS PF15798.5 GAN03571.1 - 6.6 7.3 12.8 0.35 11.5 1.6 3.5 4 0 0 4 4 4 0 Proline-rich AKT1 substrate 1 Actin PF00022.19 GAN03572.1 - 6.1e-92 308.3 0.0 2.4e-90 303.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAN03572.1 - 2.5e-05 23.3 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Pribosyl_synth PF14572.6 GAN03573.1 - 2.7e-39 135.1 1.4 1.1e-32 113.6 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 GAN03573.1 - 2.3e-37 127.5 0.0 2.2e-35 121.1 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 GAN03573.1 - 3.5e-13 49.4 0.1 6e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAN03573.1 - 0.008 15.6 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 GAN03574.1 - 2.6e-17 63.8 0.0 3.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN03574.1 - 0.0053 17.1 0.0 0.015 15.6 0.0 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN03574.1 - 0.12 12.5 0.1 3.9 7.5 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 GAN03574.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) RNA_GG_bind PF10258.9 GAN03575.1 - 0.16 12.1 0.2 0.31 11.1 0.2 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain Transposase_31 PF04754.12 GAN03577.1 - 0.0036 16.9 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative transposase, YhgA-like DUF2887 PF11103.8 GAN03577.1 - 0.0042 17.1 0.1 0.0088 16.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2887) Elongin_A PF06881.11 GAN03577.1 - 0.67 10.5 4.9 1.7 9.2 4.9 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Kelch_5 PF13854.6 GAN03578.1 - 2.7e-20 71.9 1.8 2.2e-05 24.3 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 GAN03578.1 - 4e-13 49.1 11.9 0.015 15.6 0.2 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 GAN03578.1 - 1.4e-12 47.6 20.8 6.4e-08 32.7 0.2 6.0 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 GAN03578.1 - 2.8e-10 40.0 10.3 0.00031 20.7 0.4 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN03578.1 - 0.00019 20.9 12.8 1.7 8.3 0.0 5.9 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.15 GAN03578.1 - 0.0071 16.3 10.7 9.1 6.4 0.2 5.7 5 2 0 5 5 5 2 Kelch motif HCV_NS1 PF01560.17 GAN03578.1 - 0.0074 15.0 0.1 0.012 14.3 0.1 1.3 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 DUF5305 PF17231.2 GAN03578.1 - 0.023 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) AIDA PF16168.5 GAN03578.1 - 0.04 14.0 0.7 0.49 10.5 0.1 2.7 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk Exo_endo_phos PF03372.23 GAN03579.1 - 1.4e-17 64.0 0.0 1.8e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAN03579.1 - 0.0075 16.1 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase EphA2_TM PF14575.6 GAN03580.1 - 0.0023 18.8 0.1 2.5 9.0 0.1 2.9 2 1 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain HPP PF04982.13 GAN03580.1 - 0.044 14.0 0.6 0.77 10.0 0.0 2.5 2 0 0 2 2 2 0 HPP family OppC_N PF12911.7 GAN03580.1 - 0.089 12.8 0.0 0.39 10.7 0.0 2.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Mid2 PF04478.12 GAN03580.1 - 0.14 12.0 2.2 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Yip1 PF04893.17 GAN03580.1 - 0.17 11.6 0.6 0.46 10.2 0.5 1.8 1 1 0 1 1 1 0 Yip1 domain TMEM51 PF15345.6 GAN03580.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.3 1 1 1 2 2 2 0 Transmembrane protein 51 Beta-APP PF03494.13 GAN03580.1 - 0.46 10.4 2.9 1 9.3 2.9 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Mitofilin PF09731.9 GAN03580.1 - 0.58 8.9 11.0 0.81 8.5 11.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SLC12 PF03522.15 GAN03580.1 - 0.65 9.0 6.1 0.98 8.4 6.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Hamartin PF04388.12 GAN03580.1 - 1.1 7.9 17.1 1.3 7.6 17.1 1.1 1 0 0 1 1 1 0 Hamartin protein Utp14 PF04615.13 GAN03580.1 - 1.4 7.4 12.2 1.8 7.0 12.2 1.1 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 GAN03580.1 - 2.1 6.9 14.9 3.4 6.2 14.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 GAN03580.1 - 7.7 4.5 12.8 11 4.0 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Abhydrolase_1 PF00561.20 GAN03582.1 - 2.3e-53 181.4 0.0 3.1e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN03582.1 - 0.0026 18.4 0.3 0.0044 17.7 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.19 GAN03583.1 - 1.5e-47 161.3 0.0 2.5e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAN03583.1 - 4.5e-34 117.0 0.1 6.2e-34 116.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAN03583.1 - 7.8e-07 29.4 1.3 1.9e-06 28.1 0.2 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 GAN03583.1 - 0.036 13.8 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 ACT domain Ion_trans PF00520.31 GAN03584.1 - 4.6e-11 42.4 12.8 1.2e-08 34.5 12.8 2.6 1 1 0 1 1 1 1 Ion transport protein Ilm1 PF10311.9 GAN03584.1 - 1 9.0 5.6 0.28 10.8 0.8 2.5 2 1 1 3 3 3 0 Increased loss of mitochondrial DNA protein 1 DUF1003 PF06210.11 GAN03584.1 - 5.7 7.1 6.1 1.1 9.4 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) SATase_N PF06426.14 GAN03585.1 - 0.014 15.7 0.2 0.019 15.3 0.2 1.2 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Cauli_DNA-bind PF03310.13 GAN03585.1 - 0.023 14.8 0.6 0.74 9.9 0.0 2.4 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein DUF2205 PF10224.9 GAN03585.1 - 0.071 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Short coiled-coil protein Fer4_24 PF18109.1 GAN03585.1 - 0.085 13.1 1.4 13 6.2 0.0 3.0 2 1 1 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain tRNA-synt_1c PF00749.21 GAN03587.1 - 9.4e-110 366.4 0.2 1.4e-109 365.8 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 GAN03587.1 - 1.8e-54 184.1 0.5 3.1e-54 183.3 0.5 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 GAN03587.1 - 4.9e-38 130.7 0.5 1.8e-37 128.9 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 GAN03587.1 - 3.6e-13 50.2 7.1 3.6e-13 50.2 7.1 2.2 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 rpo30_N PF12410.8 GAN03587.1 - 0.072 13.0 0.2 0.38 10.6 0.0 2.3 2 1 1 3 3 3 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Zn_Tnp_IS1595 PF12760.7 GAN03588.1 - 0.00057 19.8 1.2 0.00095 19.1 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain CxC3 PF18804.1 GAN03588.1 - 0.0055 16.5 0.2 0.0071 16.2 0.2 1.2 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Anti-TRAP PF15777.5 GAN03588.1 - 0.011 15.7 0.3 0.32 11.0 0.1 2.1 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_10 PF10058.9 GAN03588.1 - 0.015 15.1 0.3 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Lar_restr_allev PF14354.6 GAN03588.1 - 0.026 14.9 0.1 0.041 14.3 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF2387 PF09526.10 GAN03588.1 - 0.027 14.6 1.0 0.79 9.9 1.0 2.1 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.13 GAN03588.1 - 0.1 12.6 2.5 0.35 10.9 2.5 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_4 PF07975.12 GAN03588.1 - 0.27 11.5 3.0 3.9 7.8 0.4 2.2 1 1 0 2 2 2 0 TFIIH C1-like domain Ribosomal_L37ae PF01780.19 GAN03588.1 - 0.65 10.1 3.8 9.6 6.4 0.4 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family Zn_Tnp_IS1 PF03811.13 GAN03588.1 - 0.75 9.6 5.9 12 5.8 0.4 2.9 3 0 0 3 3 3 0 InsA N-terminal domain zf-RanBP PF00641.18 GAN03588.1 - 0.83 9.0 7.3 4.3 6.7 0.6 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 GAN03588.1 - 1.3 8.5 5.7 8.5 5.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ank_4 PF13637.6 GAN03589.1 - 1.7e-16 60.3 0.7 3.7e-10 40.1 0.1 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN03589.1 - 3.5e-14 53.2 1.1 3.3e-06 27.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN03589.1 - 5.9e-11 41.6 0.3 0.0019 18.5 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 GAN03589.1 - 8.1e-09 35.5 0.2 0.0017 18.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAN03589.1 - 7e-07 29.4 0.2 0.0069 16.7 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 GAN03589.1 - 7.3e-06 25.8 0.3 0.00013 21.8 0.1 2.9 2 1 0 2 2 2 1 KilA-N domain CCDC142 PF14923.6 GAN03589.1 - 0.0096 14.7 0.7 0.02 13.7 0.7 1.4 1 0 0 1 1 1 1 Coiled-coil protein 142 Ras PF00071.22 GAN03590.1 - 3.8e-44 150.1 0.7 4.6e-44 149.9 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN03590.1 - 1.6e-22 79.9 0.4 3.2e-22 79.0 0.2 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN03590.1 - 2.1e-11 43.6 0.1 2.4e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN03590.1 - 7.7e-08 32.1 0.1 9.6e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN03590.1 - 6.7e-06 25.6 0.2 8.7e-06 25.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Nuc_sug_transp PF04142.15 GAN03591.1 - 8.3e-104 347.1 28.6 5.4e-66 222.9 10.0 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 GAN03591.1 - 3.8e-05 23.0 10.2 0.0007 18.9 0.1 2.5 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.20 GAN03591.1 - 0.00015 21.9 5.3 0.00015 21.9 5.3 3.6 3 2 0 3 3 3 2 EamA-like transporter family MFAP1 PF06991.11 GAN03592.1 - 3e-73 246.3 29.2 3e-73 246.3 29.2 2.6 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing p450 PF00067.22 GAN03593.1 - 2.6e-77 260.5 0.1 4e-77 259.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 SNF5 PF04855.12 GAN03594.1 - 2.3e-65 220.7 0.3 2.3e-65 220.7 0.3 2.1 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 GAN03594.1 - 1.3e-06 27.9 2.6 2.9e-06 26.8 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Glyco_hydro_65N PF03636.15 GAN03594.1 - 0.071 12.7 1.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain Bile_Hydr_Trans PF04775.14 GAN03594.1 - 0.62 10.1 3.6 0.51 10.4 1.0 2.3 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region RRM_1 PF00076.22 GAN03595.1 - 4e-09 36.2 0.0 7.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP160 PF07918.11 GAN03595.1 - 0.027 14.2 1.2 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 CAP160 repeat TFIIA PF03153.13 GAN03595.1 - 0.21 11.5 35.4 0.034 14.1 31.9 1.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAN03595.1 - 1.5 8.3 31.4 0.27 10.8 18.9 2.4 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 GAN03595.1 - 8.2 3.4 11.4 11 3.0 11.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PX PF00787.24 GAN03596.1 - 3.1e-19 69.0 0.1 7.2e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 PX domain DUF5129 PF17173.4 GAN03596.1 - 0.022 13.9 0.6 0.028 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) DUF5523 PF17661.1 GAN03596.1 - 0.14 11.8 7.1 0.2 11.3 7.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Membralin PF09746.9 GAN03596.1 - 1.1 8.2 2.8 1.6 7.7 2.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein UFD1 PF03152.14 GAN03597.1 - 1.9e-64 216.3 0.2 2.4e-64 216.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3712 PF12505.8 GAN03598.1 - 9.2e-72 239.2 29.8 3.5e-23 82.2 2.7 7.0 6 0 0 6 6 6 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAN03598.1 - 3.3e-12 46.8 10.7 0.054 14.0 0.1 8.2 8 0 0 8 8 8 5 Late embryogenesis abundant protein RhoGEF PF00621.20 GAN03599.1 - 1.8e-48 165.2 1.7 1.8e-48 165.2 1.7 3.0 3 0 0 3 3 3 1 RhoGEF domain SH3_1 PF00018.28 GAN03599.1 - 3.3e-20 71.4 2.5 2e-09 36.9 0.7 2.9 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 GAN03599.1 - 9.3e-17 60.6 4.2 2.2e-08 33.8 1.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain PH_13 PF16652.5 GAN03599.1 - 3.2e-15 56.3 0.1 3.2e-15 56.3 0.1 5.0 2 2 3 5 5 5 1 Pleckstrin homology domain SH3_2 PF07653.17 GAN03599.1 - 1.4e-13 50.2 0.1 7.6e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain AMP-binding PF00501.28 GAN03600.1 - 6e-94 315.0 0.0 7.3e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN03600.1 - 1.2e-22 80.7 0.1 2.4e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAN03600.1 - 4.3e-18 65.0 2.5 6.1e-18 64.5 0.5 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Lambda_CIII PF02061.16 GAN03600.1 - 0.15 12.1 0.1 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Lambda Phage CIII DUF3879 PF12995.7 GAN03601.1 - 3.3e-05 23.7 1.3 3.3e-05 23.7 1.3 2.0 2 1 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3879) DUF5624 PF18538.1 GAN03601.1 - 0.035 14.2 1.2 0.47 10.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5624) WYL PF13280.6 GAN03601.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 WYL domain Usp PF00582.26 GAN03602.1 - 1.6e-14 54.6 0.0 3.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family zf-C3HC4 PF00097.25 GAN03603.1 - 1e-10 41.3 7.9 1.7e-10 40.6 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN03603.1 - 3.4e-09 36.9 9.4 5.2e-09 36.3 9.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN03603.1 - 1.2e-08 34.6 8.9 1.9e-08 34.0 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN03603.1 - 2.6e-08 33.6 7.8 3.9e-08 33.0 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN03603.1 - 3.2e-08 33.5 7.3 9.3e-08 32.0 7.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAN03603.1 - 1e-07 31.8 6.8 1.6e-07 31.2 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 GAN03603.1 - 1.8e-05 24.7 4.5 2.8e-05 24.1 4.5 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 GAN03603.1 - 2.3e-05 24.2 9.4 3.7e-05 23.5 9.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAN03603.1 - 2.4e-05 24.4 8.3 4.2e-05 23.6 8.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAN03603.1 - 9.5e-05 22.6 7.0 0.00018 21.7 7.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAN03603.1 - 0.0022 18.0 4.8 0.0036 17.3 4.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAN03603.1 - 0.01 15.4 8.3 0.017 14.7 8.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 GAN03603.1 - 0.23 10.8 1.6 0.21 10.9 0.2 1.5 1 1 0 2 2 2 0 Rtf2 RING-finger RINGv PF12906.7 GAN03603.1 - 0.37 11.0 5.9 1.3 9.2 5.9 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.6 GAN03603.1 - 0.7 9.8 5.0 1.4 8.8 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GAN03603.1 - 0.78 9.6 6.6 1.8 8.4 6.1 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS91 PF14319.6 GAN03603.1 - 0.95 9.5 4.8 0.23 11.5 0.7 1.9 1 1 1 2 2 2 0 Transposase zinc-binding domain GGACT PF06094.12 GAN03604.1 - 1.3e-15 58.1 0.0 1.8e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF3969 PF13108.6 GAN03604.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) MHC_II_beta PF00969.19 GAN03605.1 - 0.006 16.7 0.4 2.1 8.5 0.0 3.0 2 1 0 2 2 2 2 Class II histocompatibility antigen, beta domain GRIM-19 PF06212.12 GAN03605.1 - 0.079 12.9 1.4 0.19 11.7 1.4 1.6 1 0 0 1 1 1 0 GRIM-19 protein VWA_2 PF13519.6 GAN03605.1 - 0.16 12.6 5.3 0.12 13.0 2.2 2.4 2 1 0 2 2 2 0 von Willebrand factor type A domain Emaravirus_P4 PF16505.5 GAN03605.1 - 0.2 10.7 1.0 0.49 9.4 0.9 1.6 1 1 0 2 2 2 0 P4 movement protein of Emaravirus, and the 30K superfamily Uso1_p115_C PF04871.13 GAN03605.1 - 1.1 9.6 14.3 5.2 7.5 1.3 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Bcr-Abl_Oligo PF09036.10 GAN03605.1 - 8 6.5 7.3 1.4 8.9 0.9 2.8 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF3844 PF12955.7 GAN03606.1 - 5.3e-13 49.0 10.0 1.3e-12 47.8 10.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) CheR_N PF03705.15 GAN03606.1 - 0.16 11.7 0.1 24 4.7 0.0 2.6 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain EGF_3 PF12947.7 GAN03606.1 - 0.7 10.1 15.6 1.2 9.4 15.6 1.4 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.13 GAN03606.1 - 1.2 9.6 16.5 2.2 8.7 16.5 1.5 1 0 0 1 1 1 0 EGF-like domain Myb_DNA-bind_6 PF13921.6 GAN03607.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN03607.1 - 0.009 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_2 PF07719.17 GAN03608.1 - 4e-09 35.9 18.3 0.066 13.4 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAN03608.1 - 1.4e-07 32.0 0.9 0.38 11.4 0.2 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAN03608.1 - 1.8e-07 31.3 8.9 0.006 16.8 1.1 4.7 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN03608.1 - 2e-07 30.9 0.9 0.42 11.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAN03608.1 - 1.4e-06 28.7 7.9 0.075 13.5 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN03608.1 - 5.5e-05 23.1 15.4 0.2 12.0 0.3 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN03608.1 - 0.00015 21.9 9.0 1 9.6 0.1 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAN03608.1 - 0.00022 21.8 11.6 0.81 10.7 0.0 6.0 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN03608.1 - 0.001 18.5 9.6 0.015 14.7 9.7 2.7 1 1 0 1 1 1 1 MalT-like TPR region PknG_TPR PF16918.5 GAN03608.1 - 0.0061 15.3 0.1 0.0099 14.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_1 PF00515.28 GAN03608.1 - 0.019 14.7 17.6 0.08 12.8 0.4 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAN03608.1 - 0.056 13.6 1.0 4.5 7.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FOXP-CC PF16159.5 GAN03608.1 - 0.22 12.2 1.5 0.43 11.2 0.5 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain TPR_7 PF13176.6 GAN03608.1 - 0.27 11.3 2.5 8 6.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAN03608.1 - 7.9 6.3 10.5 11 5.8 0.1 5.0 6 1 1 7 7 7 0 TPR repeat Ribonuc_red_lgC PF02867.15 GAN03609.1 - 7e-181 602.3 0.0 9e-181 601.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAN03609.1 - 2.3e-23 82.0 0.0 6e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAN03609.1 - 4e-17 62.6 0.3 1.3e-16 61.0 0.1 2.1 2 0 0 2 2 2 1 ATP cone domain zf-RVT PF13966.6 GAN03609.1 - 0.00073 20.2 0.9 0.002 18.8 0.1 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF3015 PF11220.8 GAN03609.1 - 0.028 14.3 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) EnY2 PF10163.9 GAN03609.1 - 0.25 11.7 0.5 1.6 9.2 0.1 2.5 2 0 0 2 2 2 0 Transcription factor e(y)2 dCMP_cyt_deam_1 PF00383.23 GAN03610.1 - 1.6e-24 85.7 0.1 2.2e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAN03610.1 - 2.6e-20 72.6 0.0 3.3e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 GAN03610.1 - 5.9e-05 23.2 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 GAN03610.1 - 6.4e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 GAN03610.1 - 0.0011 18.9 0.1 0.0019 18.2 0.1 1.3 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase NAD1 PF18778.1 GAN03610.1 - 0.0016 18.5 0.0 0.003 17.7 0.0 1.5 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC1 PF18769.1 GAN03610.1 - 0.0051 17.0 0.0 0.0087 16.3 0.0 1.3 1 0 0 1 1 1 1 APOBEC1 APOBEC2 PF18772.1 GAN03610.1 - 0.0061 16.6 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 GAN03610.1 - 0.012 15.7 0.6 0.055 13.5 0.6 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC_N PF08210.11 GAN03610.1 - 0.018 14.9 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 GAN03610.1 - 0.04 14.0 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 PP2C PF00481.21 GAN03611.1 - 7e-79 265.1 0.0 9e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAN03611.1 - 0.00055 19.9 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) FAM70 PF14967.6 GAN03612.1 - 9.1 5.6 8.3 11 5.4 8.3 1.1 1 0 0 1 1 1 0 FAM70 protein HMG_box PF00505.19 GAN03613.1 - 1.2e-35 121.8 24.1 1.9e-15 57.0 4.1 4.4 4 0 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN03613.1 - 4.4e-31 107.3 22.7 2e-14 53.9 1.2 4.8 5 0 0 5 5 5 3 HMG-box domain DUF4666 PF15697.5 GAN03613.1 - 0.0019 18.9 2.2 0.0019 18.9 2.2 4.5 4 2 1 5 5 5 1 Domain of unknown function (DUF4666) FAA_hydrolase PF01557.18 GAN03614.1 - 2.7e-59 200.5 0.0 3.3e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF5443 PF17518.2 GAN03614.1 - 0.1 11.5 0.0 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5443) DUF2125 PF09898.9 GAN03614.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) Pyr_redox_2 PF07992.14 GAN03615.1 - 1.7e-62 211.3 7.0 2.6e-62 210.7 7.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAN03615.1 - 4.5e-32 110.6 0.4 2.3e-31 108.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAN03615.1 - 4.5e-19 68.8 0.2 4.5e-19 68.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN03615.1 - 2.9e-12 46.5 0.4 2.9e-12 46.5 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAN03615.1 - 1.2e-05 24.7 0.2 0.00017 21.0 0.1 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAN03615.1 - 1.3e-05 24.1 11.9 0.057 12.1 0.1 4.0 3 1 1 4 4 4 3 HI0933-like protein FAD_oxidored PF12831.7 GAN03615.1 - 8.4e-05 22.1 6.2 0.00015 21.3 6.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAN03615.1 - 0.0001 22.3 0.1 0.0001 22.3 0.1 2.3 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAN03615.1 - 0.00079 18.8 3.8 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 GAN03615.1 - 0.0014 18.2 0.1 0.0024 17.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 GAN03615.1 - 0.0022 17.2 0.1 0.0059 15.8 0.0 1.6 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN03615.1 - 0.012 15.8 2.1 0.012 15.8 2.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAN03615.1 - 0.015 14.4 12.4 0.045 12.8 6.6 3.0 2 1 1 3 3 3 0 FAD binding domain MCRA PF06100.11 GAN03615.1 - 0.047 12.5 0.7 2.1 7.0 0.2 2.1 2 0 0 2 2 2 0 MCRA family NAD_Gly3P_dh_N PF01210.23 GAN03615.1 - 0.094 12.7 0.0 0.094 12.7 0.0 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 GAN03615.1 - 0.28 11.8 0.0 0.28 11.8 0.0 2.1 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 GAN03615.1 - 0.31 10.6 0.0 0.31 10.6 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 GAN03615.1 - 0.4 9.7 9.7 2.5 7.1 6.3 2.8 3 1 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 GAN03615.1 - 2.2 8.8 5.0 0.49 10.9 0.1 2.4 3 0 0 3 3 2 0 Putative NAD(P)-binding Thi4 PF01946.17 GAN03615.1 - 2.5 7.3 8.0 1.9 7.7 5.2 2.3 2 1 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 GAN03615.1 - 4.6 6.4 8.8 0.68 9.1 0.4 2.5 2 1 0 2 2 2 0 FAD binding domain SPC25 PF06703.11 GAN03616.1 - 9.1e-45 152.3 3.4 1.1e-44 152.1 3.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PRP1_N PF06424.12 GAN03617.1 - 0.071 13.5 5.6 0.13 12.7 5.6 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal KCNQ2_u3 PF16642.5 GAN03617.1 - 0.67 11.0 3.2 1.5 9.9 3.2 1.5 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Peptidase_S49_N PF08496.10 GAN03617.1 - 2.6 8.1 6.1 1.9 8.5 3.4 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Gar1 PF04410.14 GAN03618.1 - 6e-38 130.0 0.0 7.3e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region OPT PF03169.15 GAN03619.1 - 9.4e-90 302.0 32.7 1.1e-89 301.8 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 GAN03619.1 - 0.092 13.0 0.1 0.34 11.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Halogen_Hydrol PF10112.9 GAN03619.1 - 7.7 6.5 4.9 2 8.4 0.5 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Methyltransf_16 PF10294.9 GAN03620.1 - 6e-33 114.0 0.0 1.3e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase cNMP_binding PF00027.29 GAN03620.1 - 1.6e-25 89.0 0.4 2e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 GAN03620.1 - 8.5e-08 31.7 0.9 2e-07 30.5 0.9 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Methyltransf_12 PF08242.12 GAN03620.1 - 0.0035 18.0 0.0 0.0095 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN03620.1 - 0.0075 17.0 0.0 0.023 15.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN03620.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAN03620.1 - 0.032 13.8 0.0 0.5 9.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Septin PF00735.18 GAN03621.1 - 5.2e-109 363.9 0.2 8.6e-109 363.2 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN03621.1 - 8.9e-09 35.4 0.0 2.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN03621.1 - 1.8e-07 30.9 2.1 2e-05 24.3 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN03621.1 - 2.8e-06 27.4 4.0 3.3e-06 27.1 0.1 2.8 3 1 1 4 4 4 1 RsgA GTPase Roc PF08477.13 GAN03621.1 - 0.00014 22.1 0.1 0.00037 20.7 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAN03621.1 - 0.0023 18.2 1.2 0.0042 17.4 0.1 2.0 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 GAN03621.1 - 0.0053 16.5 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 GAN03621.1 - 0.0055 16.1 0.1 0.013 14.9 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.16 GAN03621.1 - 0.0059 16.0 0.1 0.017 14.4 0.1 1.8 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 GAN03621.1 - 0.0068 16.0 0.1 0.021 14.4 0.1 1.8 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 GAN03621.1 - 0.0071 16.7 0.4 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 GAN03621.1 - 0.01 16.2 0.0 0.042 14.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 GAN03621.1 - 0.017 14.6 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein IIGP PF05049.13 GAN03621.1 - 0.027 13.5 0.1 0.055 12.5 0.1 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 GAN03621.1 - 0.029 13.9 0.2 0.058 12.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GAN03621.1 - 0.041 14.0 8.3 2.4 8.2 0.0 3.4 2 1 1 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.15 GAN03621.1 - 0.048 13.2 1.6 0.092 12.3 1.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.6 GAN03621.1 - 0.062 13.0 0.2 0.062 13.0 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAN03621.1 - 0.075 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAN03621.1 - 0.081 12.7 1.1 1.4 8.6 0.1 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein SecB PF02556.14 GAN03621.1 - 0.09 12.7 1.1 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit SecB AAA_33 PF13671.6 GAN03621.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 GAN03621.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAN03621.1 - 0.15 12.6 0.0 0.15 12.6 0.0 2.4 2 1 0 2 2 1 0 ABC transporter ALMT PF11744.8 GAN03621.1 - 1.2 7.9 4.0 1.8 7.3 4.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_11 PF13086.6 GAN03621.1 - 7 6.3 8.9 30 4.3 4.8 2.2 2 0 0 2 2 2 0 AAA domain TACC_C PF05010.14 GAN03622.1 - 6.7e-06 26.0 5.2 6.7e-06 26.0 5.2 1.5 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal JIP_LZII PF16471.5 GAN03622.1 - 0.0016 18.6 2.0 0.0016 18.6 2.0 2.4 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II Leu_zip PF15294.6 GAN03622.1 - 0.0018 17.9 9.0 0.0028 17.2 9.0 1.2 1 0 0 1 1 1 1 Leucine zipper APG6_N PF17675.1 GAN03622.1 - 0.0041 17.7 6.3 0.0076 16.8 6.3 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region GOLGA2L5 PF15070.6 GAN03622.1 - 0.027 13.1 8.9 0.044 12.4 8.9 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Filament PF00038.21 GAN03622.1 - 0.032 13.8 7.6 0.049 13.2 7.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein KASH_CCD PF14662.6 GAN03622.1 - 0.047 13.5 14.8 0.079 12.8 14.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 GAN03622.1 - 0.057 13.8 0.5 0.057 13.8 0.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4541 PF15074.6 GAN03622.1 - 0.11 13.1 0.1 0.33 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) DUF3584 PF12128.8 GAN03622.1 - 0.13 9.7 7.8 0.18 9.3 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GIT_CC PF16559.5 GAN03622.1 - 0.14 12.0 8.3 0.26 11.2 0.5 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 GAN03622.1 - 0.16 10.8 10.4 0.26 10.1 10.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 GAN03622.1 - 0.16 12.0 10.6 0.069 13.2 5.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Snapin_Pallidin PF14712.6 GAN03622.1 - 0.16 12.4 5.6 0.16 12.4 3.9 1.9 1 1 0 1 1 1 0 Snapin/Pallidin DUF3450 PF11932.8 GAN03622.1 - 0.23 10.8 5.3 0.43 9.8 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 GAN03622.1 - 0.25 11.1 6.2 0.26 11.1 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 GAN03622.1 - 0.35 10.9 6.3 0.95 9.5 6.3 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF745 PF05335.13 GAN03622.1 - 0.35 10.6 2.5 0.96 9.1 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Csm1_N PF18504.1 GAN03622.1 - 0.36 11.2 9.6 0.19 12.1 2.2 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain FapA PF03961.13 GAN03622.1 - 0.37 9.4 3.6 0.56 8.8 3.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc24 PF08286.11 GAN03622.1 - 0.54 10.5 10.7 1.9 8.8 10.0 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HALZ PF02183.18 GAN03622.1 - 0.54 10.5 9.7 1.4 9.2 0.1 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper zf-C3HC4_3 PF13920.6 GAN03622.1 - 0.66 9.9 6.1 0.11 12.3 1.7 2.1 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.9 GAN03622.1 - 0.67 10.0 13.3 1.1 9.3 12.6 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 GAN03622.1 - 2.1 8.8 14.7 2.9 8.4 7.0 3.2 1 1 1 2 2 2 0 Cell division protein ZapB LMBR1 PF04791.16 GAN03622.1 - 2.2 7.1 5.4 3.5 6.4 5.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TolA_bind_tri PF16331.5 GAN03622.1 - 2.7 8.1 8.1 0.48 10.5 2.0 2.5 1 1 2 3 3 3 0 TolA binding protein trimerisation Fez1 PF06818.15 GAN03622.1 - 2.8 8.3 14.1 0.3 11.5 9.8 1.5 2 0 0 2 2 1 0 Fez1 LPP PF04728.13 GAN03622.1 - 3.3 8.2 6.1 5.1 7.6 0.8 3.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper TMPIT PF07851.13 GAN03622.1 - 4.5 6.4 6.4 7 5.8 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 GAN03622.1 - 4.6 7.1 11.0 1.1 9.0 1.6 3.3 1 1 2 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 GAN03622.1 - 5.1 7.3 11.8 0.47 10.6 0.5 3.3 2 1 1 3 3 3 0 bZIP transcription factor DUF1664 PF07889.12 GAN03622.1 - 5.5 7.0 8.1 4.5 7.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 GAN03622.1 - 8.3 6.9 12.8 21 5.5 2.3 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 GAN03622.1 - 9.7 7.2 13.9 0.67 10.9 7.5 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain PSS PF03034.15 GAN03623.1 - 3.1e-113 378.1 17.5 3.1e-113 378.1 17.5 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase Glycoprotein PF03409.15 GAN03623.1 - 0.038 12.9 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein Gemini_mov PF01708.16 GAN03623.1 - 4.1 7.2 5.3 2.4 8.0 0.1 3.0 2 1 1 3 3 3 0 Geminivirus putative movement protein SAC3_GANP PF03399.16 GAN03624.1 - 1.4e-22 80.5 6.1 1.9e-20 73.4 6.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAN03624.1 - 6.2e-06 26.2 0.4 2.1e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family COX5A PF02284.16 GAN03624.1 - 0.0069 16.4 0.0 3.3 7.7 0.0 2.7 2 0 0 2 2 2 2 Cytochrome c oxidase subunit Va TPR_MalT PF17874.1 GAN03624.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 MalT-like TPR region DUF2829 PF11195.8 GAN03624.1 - 0.094 13.0 0.1 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) MCM_lid PF17855.1 GAN03624.1 - 0.14 12.6 0.4 33 5.0 0.0 2.7 2 0 0 2 2 2 0 MCM AAA-lid domain Ribosomal_S26e PF01283.19 GAN03625.1 - 1.3e-52 176.8 10.0 1.6e-52 176.5 10.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Orf78 PF06024.12 GAN03626.1 - 0.0023 18.2 1.2 0.0038 17.5 1.2 1.6 1 1 0 1 1 1 1 Orf78 (ac78) LAP1C PF05609.12 GAN03626.1 - 0.014 14.5 2.8 0.015 14.4 2.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) 7tm_1 PF00001.21 GAN03626.1 - 0.014 14.7 0.4 0.016 14.6 0.4 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) COX7a PF02238.15 GAN03626.1 - 0.018 15.5 2.9 0.028 14.8 2.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII TRIQK PF15168.6 GAN03626.1 - 0.031 14.2 0.8 0.057 13.3 0.3 1.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Phage_T7_Capsid PF05396.11 GAN03626.1 - 0.067 13.6 0.7 0.092 13.1 0.7 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Coilin_N PF15862.5 GAN03626.1 - 5.3 6.8 8.5 5.9 6.7 7.7 1.5 1 1 0 1 1 1 0 Coilin N-terminus TPR_12 PF13424.6 GAN03629.1 - 2.9e-16 59.5 8.1 4.1e-06 27.0 0.7 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN03629.1 - 1.6e-12 46.6 6.3 0.11 12.4 2.2 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAN03629.1 - 7.8e-12 44.4 12.3 0.022 14.8 0.0 6.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAN03629.1 - 9.1e-11 41.1 7.7 0.85 10.0 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAN03629.1 - 2.8e-07 30.2 4.1 0.05 13.5 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN03629.1 - 3.6e-05 23.3 1.0 0.28 10.5 0.1 3.0 3 0 0 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 GAN03629.1 - 0.00047 20.0 5.3 3.4 7.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN03629.1 - 0.0018 18.6 0.6 0.62 10.6 0.2 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAN03629.1 - 0.0026 18.2 4.3 2.4 8.7 0.4 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN03629.1 - 0.0039 17.7 9.2 0.98 10.2 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN03629.1 - 0.0074 17.0 7.4 7.7 7.6 0.4 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2989 PF11207.8 GAN03629.1 - 0.012 15.3 0.5 0.1 12.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2989) Sel1 PF08238.12 GAN03629.1 - 0.014 16.1 2.8 14 6.5 0.1 4.4 4 1 0 4 4 4 0 Sel1 repeat TPR_16 PF13432.6 GAN03629.1 - 0.02 15.5 6.2 4.3 8.1 1.0 4.2 3 2 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.9 GAN03629.1 - 0.029 14.1 0.7 1.8 8.2 0.0 3.3 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_5 PF12688.7 GAN03629.1 - 0.066 13.5 1.4 2 8.7 0.0 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat Rdx PF10262.9 GAN03630.1 - 1.1e-30 105.6 0.0 1.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Rdx family AIM5 PF17050.5 GAN03631.1 - 0.008 17.0 0.9 0.015 16.1 0.0 1.9 2 0 0 2 2 2 1 Altered inheritance of mitochondria 5 DUF2884 PF11101.8 GAN03631.1 - 0.044 13.3 0.1 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) QIL1 PF15884.5 GAN03631.1 - 0.12 13.0 0.5 0.58 10.8 0.1 2.0 1 1 1 2 2 2 0 MICOS complex subunit MIC13, QIL1 Septin PF00735.18 GAN03632.1 - 4.6e-18 65.5 0.0 4.6e-18 65.5 0.0 2.4 4 0 0 4 4 4 1 Septin RsgA_GTPase PF03193.16 GAN03632.1 - 0.00011 22.1 0.1 0.00011 22.1 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAN03632.1 - 0.0052 16.9 0.0 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAN03632.1 - 0.0058 16.9 2.1 0.021 15.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain dNK PF01712.19 GAN03632.1 - 0.0096 15.8 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA PF00004.29 GAN03632.1 - 0.013 16.0 1.8 0.75 10.2 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAN03632.1 - 0.015 15.0 0.5 0.057 13.1 0.0 2.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Ras PF00071.22 GAN03632.1 - 0.021 14.4 0.4 0.057 13.0 0.0 2.0 2 0 0 2 2 2 0 Ras family NACHT PF05729.12 GAN03632.1 - 0.036 14.0 1.0 0.15 12.0 0.0 2.4 2 1 1 3 3 3 0 NACHT domain AAA_16 PF13191.6 GAN03632.1 - 0.037 14.4 0.6 0.12 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain PRK PF00485.18 GAN03632.1 - 0.062 13.0 4.9 0.92 9.2 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 GAN03632.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAN03632.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 GAN03632.1 - 0.07 13.3 0.0 0.07 13.3 0.0 3.4 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase PAS PF00989.25 GAN03632.1 - 0.62 10.1 3.1 2 8.5 0.2 2.7 2 0 0 2 2 2 0 PAS fold ABC_tran PF00005.27 GAN03632.1 - 1 9.8 0.0 1 9.8 0.0 2.9 2 1 1 3 3 3 0 ABC transporter AAA_23 PF13476.6 GAN03632.1 - 4 7.9 0.0 4 7.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain TFIIA PF03153.13 GAN03632.1 - 8.5 6.2 32.1 6.9 6.6 17.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mce4_CUP1 PF11887.8 GAN03633.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative SMC_N PF02463.19 GAN03634.1 - 2.3e-69 233.2 0.0 5.1e-69 232.1 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAN03634.1 - 6.3e-28 97.4 0.8 8.3e-27 93.8 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 GAN03634.1 - 1.9e-19 71.0 3.8 1.9e-19 71.0 3.8 6.4 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.6 GAN03634.1 - 4.4e-14 53.0 18.3 1.7e-06 28.1 0.1 4.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAN03634.1 - 3.4e-08 33.6 24.4 3.4e-08 33.6 24.4 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAN03634.1 - 0.0077 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Matrilin_ccoil PF10393.9 GAN03634.1 - 0.71 9.8 8.8 1.8 8.5 0.2 4.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ThiS PF02597.20 GAN03634.1 - 4.2 8.1 9.3 5.7 7.7 0.1 5.1 4 0 0 4 4 4 0 ThiS family DUF3759 PF12585.8 GAN03635.1 - 9.1e-22 76.9 6.1 2.1e-21 75.8 6.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.6 GAN03635.1 - 0.00043 21.0 0.0 0.11 13.3 0.0 3.3 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like GTP_EFTU PF00009.27 GAN03636.1 - 7.6e-18 64.8 0.0 1.5e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN03636.1 - 6.7e-05 22.8 0.2 0.064 13.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 GAN03636.1 - 0.0025 17.6 0.3 0.69 9.7 0.1 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 GAN03636.1 - 0.0057 17.2 0.2 0.022 15.3 0.1 2.0 1 1 1 2 2 2 1 ABC transporter cobW PF02492.19 GAN03636.1 - 0.0099 15.5 0.3 0.15 11.6 0.3 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D2 PF03144.25 GAN03636.1 - 0.013 15.8 0.0 0.047 14.1 0.0 2.0 2 0 0 2 2 1 0 Elongation factor Tu domain 2 AAA_28 PF13521.6 GAN03636.1 - 0.068 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAN03636.1 - 0.095 12.8 0.0 0.46 10.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 GAN03636.1 - 0.12 11.8 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DAP3 PF10236.9 GAN03636.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 GAN03636.1 - 0.16 12.2 0.6 25 5.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 GAN03637.1 - 6.3e-66 222.4 0.1 1.7e-65 221.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03637.1 - 3.9e-35 121.4 0.0 7.8e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 GAN03637.1 - 3.8e-18 65.1 25.2 1.3e-10 41.0 11.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 GAN03637.1 - 4.1e-16 58.9 3.7 2.2e-10 40.5 0.3 3.6 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 GAN03637.1 - 3.9e-09 37.1 4.0 5.4e-09 36.6 1.3 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAN03637.1 - 0.0058 15.6 0.2 0.016 14.2 0.2 1.7 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 GAN03637.1 - 0.29 11.5 20.9 0.77 10.1 9.7 2.7 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.16 GAN03637.1 - 1 9.6 17.8 4.9 7.4 9.1 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger Mito_carr PF00153.27 GAN03638.1 - 1.9e-70 232.8 1.6 5.5e-24 83.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN03638.1 - 0.047 12.8 0.1 3.6 6.6 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease DUF1129 PF06570.11 GAN03639.1 - 2 7.8 7.5 9.6 5.6 7.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Sterol_MT_C PF08498.10 GAN03640.1 - 3.2e-22 78.6 0.6 1.4e-21 76.6 0.2 2.1 2 1 0 2 2 2 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAN03640.1 - 4.9e-19 68.8 0.0 9.3e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN03640.1 - 5.3e-18 65.3 0.0 9.3e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN03640.1 - 1.9e-16 60.5 0.0 4.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAN03640.1 - 2e-14 53.5 0.1 2.8e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 GAN03640.1 - 5e-09 35.8 0.1 1.7e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAN03640.1 - 7.6e-09 35.6 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN03640.1 - 2.2e-08 34.7 0.1 7.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 GAN03640.1 - 0.00038 20.1 0.0 0.0074 15.9 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Peptidase_M4 PF01447.18 GAN03640.1 - 0.00066 20.2 4.5 0.0074 16.8 2.3 2.7 3 0 0 3 3 3 1 Thermolysin metallopeptidase, catalytic domain Methyltransf_9 PF08003.11 GAN03640.1 - 0.017 14.1 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 GAN03640.1 - 0.027 14.0 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.10 GAN03640.1 - 0.04 13.5 0.1 0.081 12.5 0.1 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.15 GAN03640.1 - 0.074 12.9 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase DUF724 PF05266.14 GAN03640.1 - 0.12 12.2 0.9 6.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pkinase PF00069.25 GAN03642.1 - 1.4e-52 178.7 0.0 2.3e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03642.1 - 2.9e-21 75.9 0.0 6.7e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAN03642.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Rad51 PF08423.11 GAN03643.1 - 3.2e-126 419.8 0.1 3.9e-126 419.5 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 GAN03643.1 - 2.4e-12 46.9 0.2 3.8e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 GAN03643.1 - 2.4e-08 33.8 0.0 3.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 GAN03643.1 - 5.5e-08 33.3 0.6 1.9e-07 31.6 0.6 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 GAN03643.1 - 0.00012 21.5 1.1 0.00076 18.9 1.1 2.1 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.11 GAN03643.1 - 0.028 13.6 0.1 0.072 12.2 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.15 GAN03643.1 - 0.06 12.7 0.1 0.58 9.4 0.1 2.1 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAN03643.1 - 0.082 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GAN03644.1 - 2.6e-40 138.3 0.0 6.9e-40 137.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_4 PF13637.6 GAN03644.1 - 5.2e-16 58.8 0.1 3.2e-08 33.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN03644.1 - 7.2e-14 52.1 0.1 1.6e-07 31.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN03644.1 - 1.6e-13 50.6 0.1 2.2e-06 27.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN03644.1 - 2.6e-13 48.9 0.1 1.3e-05 25.2 0.0 3.2 3 0 0 3 3 2 2 Ankyrin repeat ClpB_D2-small PF10431.9 GAN03644.1 - 1.1e-10 41.4 0.0 7.3e-10 38.8 0.0 2.5 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAN03644.1 - 4.7e-10 39.6 0.0 3.7e-09 36.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Ank PF00023.30 GAN03644.1 - 8.9e-10 38.6 0.0 0.00053 20.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat AAA PF00004.29 GAN03644.1 - 4.6e-09 36.8 0.0 6.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAN03644.1 - 1.1e-06 28.5 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAN03644.1 - 9.2e-06 25.1 0.0 7.1e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 GAN03644.1 - 5.5e-05 23.5 0.0 0.0004 20.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAN03644.1 - 0.00053 20.5 0.1 0.017 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 GAN03644.1 - 0.00054 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_3 PF07726.11 GAN03644.1 - 0.00061 19.7 0.0 0.0049 16.7 0.0 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAN03644.1 - 0.00085 19.5 0.3 0.0029 17.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 GAN03644.1 - 0.00087 19.7 0.0 0.033 14.6 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 GAN03644.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 GAN03644.1 - 0.0095 16.5 0.3 0.049 14.2 0.0 2.5 2 1 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 GAN03644.1 - 0.024 15.0 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 GAN03644.1 - 0.038 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Phage_P2_GpE PF06528.12 GAN03644.1 - 0.075 12.6 0.2 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 Phage P2 GpE MobB PF03205.14 GAN03644.1 - 0.077 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 GAN03644.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 GAN03644.1 - 0.35 11.3 3.3 1.5 9.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain BST2 PF16716.5 GAN03644.1 - 1.5 9.5 4.2 8.9 7.0 0.1 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Ras PF00071.22 GAN03647.1 - 6e-55 185.3 0.1 6.9e-55 185.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN03647.1 - 4.8e-20 72.0 0.0 6.9e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN03647.1 - 8.4e-08 31.9 0.1 9e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN03647.1 - 6.5e-06 25.8 0.1 1.8e-05 24.4 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN03647.1 - 9.4e-05 22.4 0.7 0.13 12.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAN03647.1 - 0.00044 20.3 0.0 0.00061 19.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAN03647.1 - 0.00057 19.2 0.0 0.31 10.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SHD1 PF03983.12 GAN03648.1 - 3.6e-31 106.8 0.0 7.1e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 GAN03648.1 - 7.5e-30 102.6 9.7 1.6e-11 43.9 0.3 3.7 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 GAN03648.1 - 7.7e-28 95.8 4.4 3.7e-10 39.3 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 GAN03648.1 - 1.4e-18 66.3 0.0 4.6e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_10 PF17902.1 GAN03648.1 - 0.0059 16.6 2.9 0.1 12.7 0.0 3.6 4 0 0 4 4 4 1 SH3 domain Borrelia_P83 PF05262.11 GAN03648.1 - 0.0081 14.7 12.7 0.011 14.2 12.7 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein SAM_4 PF18017.1 GAN03648.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Macoilin PF09726.9 GAN03648.1 - 0.26 9.8 12.2 0.48 8.9 12.2 1.4 1 0 0 1 1 1 0 Macoilin family Nop53 PF07767.11 GAN03648.1 - 1.8 7.8 30.9 3.9 6.7 30.9 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Glyco_hydro_4C PF11975.8 GAN03648.1 - 6.8 6.7 0.0 6.8 6.7 0.0 2.6 2 1 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Pro_isomerase PF00160.21 GAN03649.1 - 1.1e-46 158.9 0.2 1.3e-46 158.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn_clus PF00172.18 GAN03650.1 - 5.7e-09 36.0 14.2 1.2e-08 34.9 14.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dicty_REP PF05086.12 GAN03650.1 - 2.1 6.2 7.8 2.8 5.8 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Promethin PF16015.5 GAN03651.1 - 8.3e-08 32.1 12.5 1e-07 31.8 12.5 1.2 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 GAN03651.1 - 0.0088 14.8 1.4 0.012 14.4 1.4 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MerE PF05052.12 GAN03651.1 - 0.11 12.4 10.3 0.057 13.4 7.0 1.9 1 1 1 2 2 2 0 MerE protein Sulfatase PF00884.23 GAN03652.1 - 2.2e-60 204.6 1.6 4e-60 203.8 1.6 1.4 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 GAN03652.1 - 9.2e-06 25.9 0.3 2.3e-05 24.6 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 GAN03652.1 - 0.012 14.2 0.0 0.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF229) QSregVF_b PF12843.7 GAN03652.1 - 0.025 14.4 0.2 0.056 13.3 0.2 1.5 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor An_peroxidase PF03098.15 GAN03652.1 - 0.08 11.5 0.4 0.17 10.4 0.0 1.7 2 0 0 2 2 2 0 Animal haem peroxidase Iso_dh PF00180.20 GAN03653.1 - 5e-80 269.2 0.0 6.2e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sel1 PF08238.12 GAN03654.1 - 1.7e-93 304.9 85.2 2.9e-07 30.9 0.3 29.8 29 2 0 29 29 29 20 Sel1 repeat TPR_8 PF13181.6 GAN03654.1 - 2.8e-08 33.3 24.3 0.0082 16.3 0.4 10.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAN03654.1 - 3.6e-06 27.5 33.5 1.7 9.3 0.1 11.8 11 3 1 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAN03654.1 - 3.7e-06 26.6 25.1 0.00024 20.9 0.1 9.7 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN03654.1 - 1.2e-05 25.1 60.0 0.0081 16.2 0.4 15.6 17 1 0 17 17 16 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN03654.1 - 0.0017 18.1 48.3 0.01 15.6 0.5 14.2 15 1 0 15 15 15 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAN03654.1 - 0.0038 17.8 42.1 0.043 14.5 0.9 14.3 15 2 1 16 16 15 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN03654.1 - 0.009 16.3 23.7 22 5.7 0.1 11.6 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN03654.1 - 0.017 15.4 24.8 3.4 8.0 0.3 9.5 8 2 0 8 8 8 0 Tetratricopeptide repeat ANTAR PF03861.14 GAN03654.1 - 0.12 12.2 0.2 18 5.3 0.0 3.8 3 0 0 3 3 3 0 ANTAR domain TPR_19 PF14559.6 GAN03654.1 - 0.15 12.5 23.9 6.4 7.4 0.1 10.2 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN03654.1 - 0.82 10.7 22.4 6.4 7.9 0.0 9.2 12 0 0 12 12 8 0 Tetratricopeptide repeat WWE PF02825.20 GAN03655.1 - 0.00017 22.1 0.1 0.14 12.7 0.0 2.7 2 0 0 2 2 2 2 WWE domain Abhydrolase_3 PF07859.13 GAN03656.1 - 3.1e-38 131.8 0.0 5.6e-32 111.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN03656.1 - 1.8e-10 40.3 0.0 2.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 GAN03656.1 - 0.068 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAN03656.1 - 0.11 11.9 0.1 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Mago-bind PF09282.10 GAN03657.1 - 4.6e-15 55.2 1.3 1e-14 54.1 1.3 1.6 1 0 0 1 1 1 1 Mago binding ARTD15_N PF18084.1 GAN03657.1 - 0.039 14.2 0.3 0.1 12.9 0.1 1.7 2 0 0 2 2 2 0 ARTD15 N-terminal domain E1_dh PF00676.20 GAN03659.1 - 1.8e-121 404.7 0.0 2.1e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAN03659.1 - 0.0064 15.7 0.0 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 GAN03659.1 - 0.023 15.6 1.3 0.73 10.8 0.0 2.9 2 1 0 2 2 2 0 KRTAP type 7 family COMM_domain PF07258.14 GAN03659.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 COMM domain DUF421 PF04239.12 GAN03659.1 - 0.25 11.1 0.6 0.4 10.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF421) DUF155 PF02582.14 GAN03660.1 - 6e-55 186.1 0.9 1.1e-54 185.2 0.9 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1073 PF06381.11 GAN03660.1 - 0.24 10.2 2.5 0.86 8.3 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1073) FANCI_S4 PF14678.6 GAN03661.1 - 4.1e-63 212.8 14.4 7.1e-63 212.0 10.6 2.7 2 0 0 2 2 2 1 FANCI solenoid 4 FANCI_S2 PF14676.6 GAN03661.1 - 3.3e-47 160.8 0.5 3.3e-47 160.8 0.5 3.0 3 0 0 3 3 3 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 GAN03661.1 - 1.7e-37 128.9 1.1 4.8e-37 127.5 0.1 2.4 2 0 0 2 2 2 1 FANCI helical domain 2 FANCI_HD1 PF14679.6 GAN03661.1 - 1.5e-23 82.5 0.6 1.1e-22 79.8 0.1 2.9 3 0 0 3 3 3 1 FANCI helical domain 1 FANCI_S1 PF14675.6 GAN03661.1 - 1.6e-22 80.2 7.9 2.3e-20 73.1 5.9 3.9 2 1 0 2 2 2 1 FANCI solenoid 1 FANCI_S1-cap PF14674.6 GAN03661.1 - 0.041 14.0 0.1 0.21 11.7 0.1 2.4 1 0 0 1 1 1 0 FANCI solenoid 1 cap DUF4611 PF15387.6 GAN03661.1 - 2.2 8.6 7.2 0.4 10.9 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) W2 PF02020.18 GAN03662.1 - 1e-17 64.0 0.2 4.1e-17 62.1 0.2 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon PI3Ka PF00613.20 GAN03662.1 - 0.014 14.8 0.3 0.17 11.3 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) APC1_C PF18122.1 GAN03662.1 - 0.022 14.7 0.1 0.13 12.2 0.0 2.2 2 1 0 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain CdiI_2 PF18593.1 GAN03662.1 - 0.026 15.2 0.1 0.23 12.1 0.1 2.3 2 0 0 2 2 2 0 CdiI immunity protein DIL PF01843.19 GAN03662.1 - 0.029 14.6 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 DIL domain Rep_fac_C PF08542.11 GAN03663.1 - 1.1e-22 80.3 0.0 2.2e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAN03663.1 - 2.2e-12 47.1 0.0 9.6e-10 38.5 0.0 2.5 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 GAN03663.1 - 4.2e-12 46.6 0.0 7.4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAN03663.1 - 1.4e-06 28.4 0.0 4.7e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAN03663.1 - 1.8e-05 25.2 0.0 0.0002 21.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 GAN03663.1 - 0.00015 21.6 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAN03663.1 - 0.00023 21.5 0.1 0.34 11.2 0.1 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 GAN03663.1 - 0.00023 21.1 0.0 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 GAN03663.1 - 0.0011 18.4 0.0 0.0074 15.7 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 GAN03663.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 GAN03663.1 - 0.0048 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 GAN03663.1 - 0.0054 15.8 0.0 0.0096 14.9 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 GAN03663.1 - 0.0057 16.6 0.1 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_assoc_2 PF16193.5 GAN03663.1 - 0.0084 16.4 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 GAN03663.1 - 0.013 15.3 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAN03663.1 - 0.017 14.7 0.0 0.088 12.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 GAN03663.1 - 0.021 15.2 0.1 0.14 12.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 GAN03663.1 - 0.055 12.9 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 GAN03663.1 - 0.074 13.6 0.2 0.26 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 GAN03663.1 - 0.12 11.7 0.0 17 4.7 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein Trimer_CC PF08954.11 GAN03663.1 - 0.55 9.8 3.0 16 5.2 0.1 2.7 3 0 0 3 3 3 0 Trimerisation motif Pkinase PF00069.25 GAN03665.1 - 8.5e-63 212.2 0.1 1.1e-62 211.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03665.1 - 3e-21 75.9 0.0 8.2e-20 71.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN03665.1 - 9.7e-07 28.9 0.9 3.6e-06 27.1 0.3 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAN03665.1 - 0.0061 16.2 0.2 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 GAN03665.1 - 0.0087 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAN03665.1 - 0.022 14.1 0.2 0.039 13.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 GAN03666.1 - 7.9e-51 172.4 0.0 9e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FYVE PF01363.21 GAN03667.1 - 8e-14 51.5 6.9 1.3e-13 50.9 6.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-HIT PF04438.16 GAN03667.1 - 0.0066 16.3 1.0 0.0066 16.3 1.0 2.0 2 0 0 2 2 2 1 HIT zinc finger zf-AN1 PF01428.16 GAN03667.1 - 5.9 7.1 13.6 1.9 8.7 9.9 1.9 2 0 0 2 2 2 0 AN1-like Zinc finger ATP-synt_E_2 PF08112.11 GAN03668.1 - 0.067 13.5 0.4 0.067 13.5 0.4 2.6 3 0 0 3 3 3 0 ATP synthase epsilon subunit DUF3106 PF11304.8 GAN03668.1 - 0.12 12.9 13.8 0.37 11.3 11.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Plk4_PB2 PF18409.1 GAN03668.1 - 2.7 8.7 5.8 2.2 9.0 1.1 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Endonuc_Holl PF10107.9 GAN03668.1 - 3.6 7.4 6.8 1.1 9.0 4.0 1.6 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase OmpH PF03938.14 GAN03668.1 - 3.9 7.8 17.2 6.1 7.2 17.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 GAN03668.1 - 6.5 6.2 8.8 7.6 6.0 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit 7tm_3 PF00003.22 GAN03669.1 - 6.8e-06 26.0 18.9 6.8e-06 26.0 18.9 1.5 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR RGS PF00615.19 GAN03669.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_1 PF00001.21 GAN03669.1 - 0.73 9.1 12.6 0.019 14.3 3.1 2.7 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF2615 PF11027.8 GAN03669.1 - 4.9 7.4 4.7 2 8.6 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF1980 PF09323.10 GAN03671.1 - 0.076 12.9 0.3 12 5.8 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) zf-Tim10_DDP PF02953.15 GAN03672.1 - 1.6e-20 72.5 2.4 2e-20 72.2 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps54 PF07928.12 GAN03672.1 - 0.0033 17.8 0.0 0.0042 17.5 0.0 1.1 1 0 0 1 1 1 1 Vps54-like protein UBN_AB PF14075.6 GAN03673.1 - 4.2e-35 121.4 6.6 4.2e-35 121.4 6.6 3.8 2 1 1 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 GAN03673.1 - 4.1e-10 39.5 4.9 4.1e-10 39.5 4.9 2.5 1 1 1 2 2 2 1 HPC2 and ubinuclein domain CSG2 PF16965.5 GAN03673.1 - 1.3 7.9 3.5 2.5 6.9 3.5 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator PIP5K PF01504.18 GAN03674.1 - 3.3e-39 134.8 0.4 8.1e-32 110.5 1.1 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GAN03674.1 - 9.9e-28 97.0 0.2 1.5e-27 96.4 0.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GAN03674.1 - 0.17 12.0 2.6 0.54 10.4 2.6 1.9 1 0 0 1 1 1 0 FYVE zinc finger Oxidored_FMN PF00724.20 GAN03675.1 - 4.2e-96 322.2 0.0 4.7e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family XAF1_C PF18608.1 GAN03676.1 - 0.015 14.9 1.1 0.015 14.9 1.1 2.4 1 1 1 2 2 2 0 XIAP-associated factor 1 C-terminal domain SAD_SRA PF02182.17 GAN03677.1 - 0.5 10.0 3.0 0.4 10.4 0.8 1.8 1 1 1 2 2 2 0 SAD/SRA domain Mpp10 PF04006.12 GAN03678.1 - 5.7e-160 533.7 87.5 7.1e-160 533.4 87.5 1.0 1 0 0 1 1 1 1 Mpp10 protein TMPIT PF07851.13 GAN03678.1 - 4.7 6.4 7.6 0.76 9.0 2.8 2.2 2 0 0 2 2 2 0 TMPIT-like protein PLDc PF00614.22 GAN03679.1 - 2.3e-14 52.9 0.6 6.7e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAN03679.1 - 1.1e-13 51.2 0.0 6.5e-08 32.5 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 GAN03679.1 - 2.1e-09 37.3 3.5 1.3e-08 34.8 0.1 3.7 4 0 0 4 4 4 1 PX domain Dynamin_N PF00350.23 GAN03680.1 - 1.1e-17 64.6 0.5 1.1e-17 64.6 0.5 3.2 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 GAN03680.1 - 2.6e-11 43.6 4.1 5.9e-11 42.4 0.3 3.2 3 1 0 3 3 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN03680.1 - 7.9e-08 32.1 8.0 3.4e-06 26.8 7.7 3.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN03680.1 - 2.8e-05 24.1 1.5 0.47 10.3 0.2 3.7 2 1 1 3 3 3 2 RsgA GTPase Roc PF08477.13 GAN03680.1 - 0.00015 21.9 0.1 0.023 14.9 0.0 3.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAN03680.1 - 0.0011 18.6 5.2 0.13 11.8 0.2 3.2 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 GAN03680.1 - 0.0019 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Apolipoprotein PF01442.18 GAN03680.1 - 0.012 15.5 1.1 0.012 15.5 1.1 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FeoB_N PF02421.18 GAN03680.1 - 0.015 14.9 0.9 2.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 GAN03680.1 - 0.016 15.0 0.3 6.6 6.5 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_D PF01813.17 GAN03680.1 - 0.038 13.8 7.1 0.069 13.0 2.5 2.4 2 0 0 2 2 2 0 ATP synthase subunit D TsaE PF02367.17 GAN03680.1 - 0.05 13.6 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAN03680.1 - 0.053 13.9 3.5 0.21 12.0 0.0 3.3 3 2 0 3 3 3 0 AAA ATPase domain DUF445 PF04286.12 GAN03680.1 - 0.07 12.9 11.0 0.76 9.5 3.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) SPACA7 PF15307.6 GAN03680.1 - 0.074 13.3 1.2 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 AAA_18 PF13238.6 GAN03680.1 - 0.2 12.2 1.6 2.6 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 GAN03680.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.2 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea DUF3958 PF13125.6 GAN03680.1 - 0.57 10.4 13.4 0.82 9.9 4.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) DUF2924 PF11149.8 GAN03680.1 - 1.8 9.0 4.3 4.8 7.6 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) Spore_II_R PF09551.10 GAN03680.1 - 2.1 8.8 11.5 0.35 11.3 0.4 3.2 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) PMC2NT PF08066.12 GAN03680.1 - 2.8 8.7 7.5 5.7 7.7 0.8 3.2 2 1 0 2 2 2 0 PMC2NT (NUC016) domain SRPRB PF09439.10 GAN03680.1 - 2.9 7.3 11.6 2 7.8 0.0 3.8 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 GAN03680.1 - 3.3 8.2 16.3 18 5.7 4.1 3.5 2 1 0 2 2 2 0 AAA domain INCENP_ARK-bind PF03941.15 GAN03681.1 - 1.2e-06 28.3 1.4 1.9e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region She9_MDM33 PF05546.11 GAN03682.1 - 2.8e-69 232.9 9.4 4.4e-69 232.3 9.4 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family LpqV PF17301.2 GAN03682.1 - 0.094 13.0 1.8 5.2 7.3 0.0 3.3 3 0 0 3 3 3 0 Putative lipoprotein LpqV WD40 PF00400.32 GAN03683.1 - 4.1e-44 147.7 30.0 4e-08 33.8 0.4 9.0 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 GAN03683.1 - 1.5e-13 50.4 0.5 3.2e-13 49.3 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03683.1 - 2.6e-11 43.1 0.3 6.4e-11 41.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain bZIP_2 PF07716.15 GAN03683.1 - 1.8e-09 37.5 7.4 6.1e-09 35.8 7.4 2.0 1 0 0 1 1 1 1 Basic region leucine zipper Nup160 PF11715.8 GAN03683.1 - 3.4e-06 26.0 18.2 0.089 11.4 0.0 6.3 2 2 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN03683.1 - 7.9e-05 22.9 1.8 2.2 8.7 0.0 4.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 GAN03683.1 - 0.00051 19.9 0.0 0.0022 17.9 0.0 2.1 1 0 0 1 1 1 1 F-box BBS2_Mid PF14783.6 GAN03683.1 - 0.036 14.1 0.0 1.2 9.3 0.0 3.2 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 GAN03683.1 - 0.055 12.4 5.6 11 4.8 0.0 4.1 2 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain MCM PF00493.23 GAN03684.1 - 1.2e-102 341.7 0.0 1.9e-102 341.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAN03684.1 - 3.2e-31 107.8 0.3 5.8e-31 107.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAN03684.1 - 3.7e-20 72.1 1.6 8.6e-20 71.0 1.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAN03684.1 - 3.7e-12 46.7 1.2 6.2e-12 46.0 0.2 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAN03684.1 - 2.6e-07 30.3 0.1 1.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAN03684.1 - 2.4e-06 27.6 0.0 7.5e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 GAN03684.1 - 0.00016 21.5 0.8 0.00054 19.7 0.8 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 GAN03684.1 - 0.017 15.0 0.2 0.086 12.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_tranf_2_4 PF13704.6 GAN03684.1 - 0.12 12.9 1.5 0.86 10.2 0.3 2.7 2 1 0 2 2 1 0 Glycosyl transferase family 2 Sigma54_activat PF00158.26 GAN03684.1 - 0.13 12.0 0.0 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Zn-ribbon_8 PF09723.10 GAN03684.1 - 0.54 10.4 1.9 1.3 9.2 1.9 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Baculo_LEF-11 PF06385.12 GAN03685.1 - 2.9 8.4 8.0 14 6.2 2.6 2.6 2 0 0 2 2 2 0 Baculovirus LEF-11 protein MFS_1 PF07690.16 GAN03686.1 - 3.1e-15 56.0 33.4 3.1e-15 56.0 33.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.12 GAN03686.1 - 0.012 16.0 0.1 0.012 16.0 0.1 4.5 6 1 1 7 7 7 0 Protein of unknown function (DUF983) UPF1_Zn_bind PF09416.10 GAN03687.1 - 2e-75 251.9 5.0 4.4e-75 250.8 4.3 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GAN03687.1 - 8.5e-58 195.3 0.0 1.7e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAN03687.1 - 6.7e-51 173.6 3.3 6.3e-28 98.3 0.3 2.6 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 GAN03687.1 - 1.7e-32 111.5 0.0 4.8e-32 110.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GAN03687.1 - 5.5e-14 52.3 0.1 3e-13 49.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAN03687.1 - 2.3e-11 44.2 0.1 1e-10 42.1 0.1 2.1 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 GAN03687.1 - 8.9e-06 25.8 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 GAN03687.1 - 2e-05 24.4 0.0 0.25 11.1 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 GAN03687.1 - 0.00034 20.0 1.5 0.0046 16.3 0.1 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 GAN03687.1 - 0.00037 20.4 0.0 0.00094 19.1 0.0 1.8 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 GAN03687.1 - 0.01 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.29 GAN03687.1 - 0.012 15.4 0.1 0.041 13.7 0.1 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_10 PF12846.7 GAN03687.1 - 0.014 14.4 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 GAN03687.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_S13_N PF08069.12 GAN03687.1 - 0.046 13.8 1.3 0.37 10.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain AAA_25 PF13481.6 GAN03687.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAN03687.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 GAN03687.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 GAN03687.1 - 0.14 11.6 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 GAN03687.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ribosomal_L36e PF01158.18 GAN03688.1 - 5.8e-35 119.4 6.2 9.5e-34 115.5 6.2 1.9 1 1 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.12 GAN03688.1 - 0.0076 16.1 0.2 0.01 15.7 0.2 1.2 1 0 0 1 1 1 1 LemA family 4HB_MCP_1 PF12729.7 GAN03688.1 - 0.029 13.9 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction HAD PF12710.7 GAN03690.1 - 6.3e-10 39.8 0.1 1.2e-09 38.9 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN03690.1 - 0.0042 17.4 0.1 0.014 15.7 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN03690.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAN03690.1 - 0.07 12.5 0.2 6.7 6.0 0.0 2.4 2 1 0 2 2 2 0 Putative Phosphatase MIT PF04212.18 GAN03691.1 - 1.6e-07 31.3 0.3 5.1e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain FAM76 PF16046.5 GAN03691.1 - 0.015 14.7 2.8 0.02 14.3 2.8 1.3 1 0 0 1 1 1 0 FAM76 protein DUF2225 PF09986.9 GAN03691.1 - 0.039 13.7 0.7 0.058 13.1 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) BET PF17035.5 GAN03691.1 - 0.079 13.1 0.4 12 6.2 0.1 2.5 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation YABBY PF04690.13 GAN03691.1 - 4.4 7.8 7.3 0.57 10.7 1.1 2.3 1 1 1 2 2 2 0 YABBY protein DUF4698 PF15769.5 GAN03691.1 - 9.5 5.1 11.3 3.3 6.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4698) Spermine_synth PF01564.17 GAN03692.1 - 3.5e-69 232.0 0.0 6.2e-69 231.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain RVT_1 PF00078.27 GAN03692.1 - 1.9e-18 66.8 0.0 4.8e-17 62.2 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spermine_synt_N PF17284.2 GAN03692.1 - 5e-17 61.5 0.6 1.1e-16 60.4 0.6 1.7 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAN03692.1 - 0.0015 19.2 0.0 0.0032 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 GAN03692.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PGK PF00162.19 GAN03693.1 - 3.6e-153 510.0 1.2 4e-153 509.8 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FAM25 PF15825.5 GAN03693.1 - 0.017 15.5 0.8 0.27 11.6 0.0 2.5 2 0 0 2 2 2 0 FAM25 family DUF3808 PF10300.9 GAN03694.1 - 2.6e-92 310.1 16.3 1.4e-91 307.6 11.3 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 GAN03694.1 - 8e-07 28.7 6.0 0.36 11.1 0.1 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat YCII PF03795.14 GAN03694.1 - 0.0028 18.0 0.0 4 7.9 0.0 2.9 2 0 0 2 2 2 2 YCII-related domain TPR_6 PF13174.6 GAN03694.1 - 0.1 13.3 7.8 42 5.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN03694.1 - 0.12 11.7 4.0 7 5.9 0.1 2.9 3 0 0 3 3 3 0 MalT-like TPR region TPR_11 PF13414.6 GAN03694.1 - 0.16 11.7 3.7 3.2 7.5 0.4 3.8 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 GAN03694.1 - 0.44 10.4 14.7 1 9.3 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN03694.1 - 0.55 10.6 9.1 18 5.7 0.1 5.5 5 1 1 7 7 7 0 Tetratricopeptide repeat FPV060 PF17614.2 GAN03695.1 - 0.0034 16.8 0.1 0.0037 16.7 0.1 1.1 1 0 0 1 1 1 1 Viral CC-type chemokine MMR_HSR1_Xtn PF16897.5 GAN03697.1 - 1.1e-41 141.1 1.6 8.6e-41 138.3 0.9 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GAN03697.1 - 3.6e-23 81.4 0.1 6.6e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GAN03697.1 - 1.7e-21 76.4 0.0 3.9e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN03697.1 - 3.2e-11 43.0 0.1 1.3e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 GAN03697.1 - 0.0041 16.2 2.0 0.0074 15.3 0.4 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAN03697.1 - 0.0067 16.5 0.3 1.8 8.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 GAN03697.1 - 0.015 14.8 0.3 14 5.1 0.0 3.5 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN03697.1 - 0.71 9.8 3.5 8 6.3 0.0 3.2 3 1 1 4 4 4 0 RsgA GTPase SQHop_cyclase_C PF13243.6 GAN03698.1 - 1.7e-47 162.1 0.3 1.5e-43 149.1 0.1 2.9 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAN03698.1 - 2.3e-46 158.2 0.3 9.7e-42 143.0 0.0 3.1 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 GAN03698.1 - 7.5e-26 89.6 7.0 3.8e-08 32.9 0.0 5.4 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat ALS_ss_C PF10369.9 GAN03698.1 - 2.3e-17 62.9 0.2 3.3e-16 59.2 0.0 2.7 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 GAN03698.1 - 9e-12 44.6 0.1 2e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 GAN03698.1 - 1.9e-06 27.6 0.0 5.7e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 ACT domain TED_complement PF07678.14 GAN03698.1 - 6.7e-06 25.3 0.8 0.00028 20.0 0.2 3.1 2 1 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 GAN03698.1 - 0.0011 18.3 0.7 2 7.7 0.0 3.3 2 1 2 4 4 4 2 Pectic acid lyase Macro PF01661.21 GAN03699.1 - 2e-35 121.3 0.2 3e-35 120.8 0.2 1.2 1 0 0 1 1 1 1 Macro domain Peptidase_M3 PF01432.20 GAN03700.1 - 2.1e-117 393.2 0.0 3.3e-117 392.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 GAN03700.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like MMM1 PF10296.9 GAN03701.1 - 1.3e-14 54.0 1.9 7.3e-12 45.0 0.5 2.4 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Metallophos PF00149.28 GAN03702.1 - 2e-36 126.4 0.1 3.8e-36 125.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN03702.1 - 8.2e-14 51.8 0.1 1.9e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain zf-H2C2_2 PF13465.6 GAN03703.1 - 8.8e-09 35.4 7.8 1.2e-07 31.8 2.9 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAN03703.1 - 8.3e-05 22.8 5.0 8.3e-05 22.8 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN03703.1 - 8.7e-05 23.0 13.5 0.0074 17.0 3.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GAN03703.1 - 0.015 15.0 1.3 0.046 13.5 1.3 1.9 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 GAN03703.1 - 0.026 14.8 3.7 1.4 9.3 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 GAN03703.1 - 0.034 14.3 3.1 0.55 10.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 GAN03703.1 - 0.035 14.4 6.3 0.28 11.6 0.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sprouty PF05210.13 GAN03703.1 - 0.086 13.2 3.3 0.16 12.4 3.3 1.5 1 0 0 1 1 1 0 Sprouty protein (Spry) MRP-S25 PF13741.6 GAN03704.1 - 4.8e-44 150.6 3.9 5.4e-44 150.5 3.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 GAN03704.1 - 9.1e-07 29.2 0.3 0.02 15.1 0.1 2.8 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S23 DUF3808 PF10300.9 GAN03705.1 - 4.5e-68 230.1 6.1 6.5e-68 229.6 6.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 GAN03705.1 - 0.17 12.1 2.9 26 5.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUP PF00674.18 GAN03705.1 - 0.65 10.2 5.1 3.8 7.7 1.4 2.8 3 0 0 3 3 3 0 DUP family U1snRNP70_N PF12220.8 GAN03706.1 - 3.8e-25 88.3 1.3 8.7e-25 87.2 1.3 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 GAN03706.1 - 1.3e-17 63.3 0.0 2.3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAN03706.1 - 0.0084 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 GAN03706.1 - 0.047 13.9 0.5 0.071 13.3 0.5 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter IPPT PF01715.17 GAN03706.1 - 0.095 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 IPP transferase BRAP2 PF07576.12 GAN03706.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 PAP_central PF04928.17 GAN03707.1 - 2.5e-102 341.1 0.1 3.3e-102 340.7 0.1 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAN03707.1 - 4.4e-43 146.9 0.1 7.6e-43 146.1 0.1 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAN03707.1 - 0.0001 22.5 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Methyltransf_25 PF13649.6 GAN03708.1 - 9.6e-14 51.9 0.0 4.1e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN03708.1 - 1.1e-12 48.5 0.0 3.8e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN03708.1 - 2.2e-11 43.8 0.0 3e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN03708.1 - 2e-08 34.3 0.0 4.5e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN03708.1 - 1.7e-07 30.8 0.0 2.3e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN03708.1 - 4.4e-05 24.2 0.0 0.0019 18.9 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN03708.1 - 0.0081 15.6 0.0 0.065 12.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 GAN03708.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 GAN03708.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Mito_carr PF00153.27 GAN03709.1 - 1e-71 237.0 2.1 5e-24 84.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF382 PF04037.13 GAN03710.1 - 1e-55 187.3 0.7 1e-55 187.3 0.7 3.8 4 1 1 5 5 5 1 Domain of unknown function (DUF382) PSP PF04046.16 GAN03710.1 - 2.7e-21 75.2 6.0 6.5e-21 73.9 6.0 1.7 1 0 0 1 1 1 1 PSP Ribosomal_L12_N PF16320.5 GAN03710.1 - 0.16 11.7 1.9 0.54 10.0 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain UPF0061 PF02696.14 GAN03711.1 - 5.7e-135 450.7 0.0 7.4e-135 450.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family adh_short PF00106.25 GAN03712.1 - 3.9e-50 170.0 0.3 5e-50 169.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN03712.1 - 7.7e-30 104.2 0.1 1e-29 103.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN03712.1 - 2.1e-08 34.3 0.0 3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 GAN03712.1 - 0.011 16.3 0.1 0.045 14.3 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 GAN03712.1 - 0.012 15.1 0.2 0.037 13.5 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family USP8_dimer PF08969.11 GAN03712.1 - 0.085 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain DUF4316 PF14195.6 GAN03712.1 - 0.18 11.6 0.8 1.6 8.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4316) PTS_IIB PF02302.17 GAN03712.1 - 0.42 11.4 1.6 42 4.9 0.0 2.8 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit Cation_ATPase_C PF00689.21 GAN03714.1 - 7.4e-45 152.9 12.8 7.4e-45 152.9 12.8 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAN03714.1 - 3.7e-35 121.1 1.0 3.7e-35 121.1 1.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAN03714.1 - 2e-20 72.6 0.0 4.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN03714.1 - 6.2e-17 62.6 0.1 5.3e-16 59.6 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN03714.1 - 3.4e-09 36.2 0.1 7.5e-07 28.7 0.1 2.7 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN03714.1 - 8.9e-05 22.4 0.2 0.0014 18.4 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.32 GAN03715.1 - 4.8e-13 47.6 10.7 7.9e-06 25.1 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAN03715.1 - 1.6e-10 40.0 10.5 0.00011 21.8 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 GAN03715.1 - 2.5e-10 40.7 4.8 9.7e-05 22.7 1.3 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAN03715.1 - 8.7e-08 31.3 5.1 0.0052 16.2 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAN03715.1 - 6.7e-06 25.9 13.2 0.00093 19.0 1.3 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_11 PF08976.11 GAN03715.1 - 0.0022 18.9 0.1 0.0061 17.4 0.1 1.7 1 1 1 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 GAN03715.1 - 0.0032 17.7 0.1 1 9.8 0.0 2.8 2 2 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 GAN03715.1 - 0.073 13.0 0.9 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 GAN03715.1 - 0.39 10.9 7.1 27 5.1 4.3 3.1 2 1 0 2 2 2 0 Dockerin type I domain UPF0047 PF01894.17 GAN03716.1 - 0.067 13.4 0.3 0.26 11.4 0.3 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 FAD_binding_7 PF03441.14 GAN03717.1 - 2e-64 216.8 0.4 4.5e-64 215.7 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAN03717.1 - 2.7e-26 92.5 0.0 5.9e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase LMWPc PF01451.21 GAN03718.1 - 1.6e-48 164.7 0.0 1.8e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PTR2 PF00854.21 GAN03719.1 - 8.3e-92 308.0 11.2 1.1e-91 307.6 9.2 2.0 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 GAN03719.1 - 7.8e-07 28.3 23.5 1.2e-05 24.4 23.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Ferlin_C PF16165.5 GAN03719.1 - 0.029 14.3 1.9 6 6.8 0.0 2.5 2 0 0 2 2 2 0 Ferlin C-terminus YWFCY PF14293.6 GAN03719.1 - 0.07 13.5 0.2 22 5.4 0.1 2.8 2 0 0 2 2 2 0 YWFCY protein FA_desaturase PF00487.24 GAN03719.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.8 2 1 1 3 3 3 0 Fatty acid desaturase DUF3087 PF11286.8 GAN03719.1 - 0.15 11.5 0.7 0.43 10.0 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) MFS_1 PF07690.16 GAN03720.1 - 5.7e-39 134.0 31.4 8.9e-39 133.4 31.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN03720.1 - 4.8e-13 48.8 29.5 6.4e-12 45.1 12.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TAFH PF07531.14 GAN03720.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF WD40 PF00400.32 GAN03721.1 - 3.8e-10 40.2 0.3 0.084 13.8 0.0 6.3 6 1 1 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN03721.1 - 9e-09 35.5 0.0 1.8 8.9 0.0 5.8 1 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAN03721.1 - 0.0019 16.8 0.0 0.024 13.2 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Vps16_N PF04841.13 GAN03721.1 - 0.0088 14.8 0.0 0.087 11.6 0.0 2.1 2 0 0 2 2 2 1 Vps16, N-terminal region GOLD_2 PF13897.6 GAN03721.1 - 1.6 9.3 0.0 1.6 9.3 0.0 4.2 3 1 0 4 4 4 0 Golgi-dynamics membrane-trafficking ASXH PF13919.6 GAN03722.1 - 1.8e-18 66.9 4.7 4.5e-18 65.6 4.7 1.7 1 1 0 1 1 1 1 Asx homology domain SNF2_N PF00176.23 GAN03723.1 - 4e-48 163.9 2.0 7.9e-48 163.0 2.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN03723.1 - 2.1e-11 44.2 0.6 5.4e-11 42.8 0.6 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN03723.1 - 0.00055 20.0 2.3 0.18 11.8 0.0 3.7 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit hEGF PF12661.7 GAN03723.1 - 3.8 8.3 5.3 5.6 7.8 0.7 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF LRR_8 PF13855.6 GAN03725.1 - 0.096 12.5 0.3 22 4.9 0.1 3.6 3 1 0 3 3 3 0 Leucine rich repeat TauD PF02668.16 GAN03726.1 - 2.1e-57 195.0 0.5 2.5e-57 194.7 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box-like PF12937.7 GAN03727.1 - 2.3e-06 27.4 0.0 6.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03727.1 - 0.0028 17.5 0.1 0.014 15.2 0.0 2.3 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 GAN03727.1 - 0.01 16.2 9.6 20 5.8 0.1 6.3 5 2 3 8 8 8 0 Leucine Rich repeats (2 copies) NDUFA12 PF05071.16 GAN03727.1 - 0.17 12.7 0.8 1.4 9.8 0.1 2.5 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 WD40 PF00400.32 GAN03728.1 - 2.2e-14 53.6 11.0 0.014 16.2 0.2 6.8 5 1 1 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAN03728.1 - 0.005 15.9 0.1 0.49 9.3 0.0 2.9 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Hexokinase_2 PF03727.16 GAN03729.1 - 7.7e-67 225.2 0.0 1e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN03729.1 - 3.8e-59 199.9 0.0 6.4e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Pkinase PF00069.25 GAN03730.1 - 1.9e-40 138.9 0.8 1.5e-20 73.7 0.2 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03730.1 - 1.7e-11 43.9 0.1 8.5e-08 31.8 0.0 3.9 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN03730.1 - 8.1e-05 21.6 0.1 8.1e-05 21.6 0.1 2.5 1 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAN03730.1 - 0.0025 17.8 0.0 0.18 11.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAN03730.1 - 0.02 14.2 0.1 0.064 12.6 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 GAN03731.1 - 9e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03731.1 - 0.11 12.4 0.0 0.47 10.4 0.0 2.1 1 0 0 1 1 1 0 F-box domain CbeA_antitoxin PF06154.11 GAN03731.1 - 0.12 13.0 0.3 4 8.1 0.1 2.9 2 1 0 3 3 3 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A O-FucT PF10250.9 GAN03732.1 - 5.5e-10 39.5 0.1 5.4e-09 36.2 0.1 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1233 PF06806.12 GAN03732.1 - 0.29 10.7 1.4 73 3.1 0.0 3.4 3 0 0 3 3 3 0 Putative excisionase (DUF1233) COX16 PF14138.6 GAN03733.1 - 2.5e-30 104.8 0.0 3.1e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Glutaredoxin PF00462.24 GAN03734.1 - 2.6e-18 66.0 0.0 2.3e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 GAN03734.1 - 1.1e-14 54.3 0.0 2.4e-14 53.1 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 GAN03734.1 - 0.0093 15.9 0.2 0.24 11.4 0.0 2.6 2 1 1 3 3 3 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 GAN03734.1 - 0.017 14.5 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phosducin PF02114.16 GAN03734.1 - 0.028 13.3 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosducin Thioredoxin_8 PF13905.6 GAN03734.1 - 0.048 14.0 0.1 2.1 8.7 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin-like GP24_25 PF17388.2 GAN03734.1 - 0.065 13.2 0.1 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 DUF3658 PF12395.8 GAN03734.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function RRM_1 PF00076.22 GAN03737.1 - 5.5e-15 54.9 0.1 8e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN03737.1 - 0.00029 20.8 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Arrestin_C PF02752.22 GAN03738.1 - 2.7e-07 31.1 0.4 2.7e-07 31.1 0.4 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 GAN03738.1 - 0.00055 19.6 0.1 0.054 13.0 0.0 2.5 2 0 0 2 2 2 2 SpoOM protein Arrestin_N PF00339.29 GAN03738.1 - 0.029 14.4 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain zf-RING_2 PF13639.6 GAN03740.1 - 2.9e-13 49.9 7.6 4.4e-13 49.3 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN03740.1 - 5.3e-09 35.8 7.4 8.1e-09 35.2 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN03740.1 - 1.3e-08 35.0 7.5 3.7e-08 33.5 7.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN03740.1 - 1.1e-07 31.7 5.3 1.7e-07 31.1 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAN03740.1 - 1.3e-07 31.2 6.5 1.3e-07 31.2 6.5 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAN03740.1 - 2.1e-06 27.5 4.5 3.2e-06 26.9 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN03740.1 - 3.3e-06 27.0 2.0 3.3e-06 27.0 2.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAN03740.1 - 3.6e-06 26.7 7.6 6.1e-06 26.0 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN03740.1 - 7.2e-06 25.8 6.0 1.3e-05 24.9 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAN03740.1 - 0.00011 22.1 1.9 0.00021 21.3 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAN03740.1 - 0.0022 17.6 4.6 0.0037 16.9 4.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 GAN03740.1 - 0.0069 16.2 0.4 0.012 15.4 0.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GAN03740.1 - 0.29 11.3 3.8 0.48 10.6 3.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 GAN03740.1 - 0.29 11.3 7.5 0.58 10.3 7.5 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 GAN03740.1 - 0.38 10.9 5.5 1 9.6 5.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 GAN03740.1 - 0.85 9.6 5.6 1.9 8.4 5.7 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 GAN03740.1 - 1 9.7 3.3 2 8.8 3.3 1.5 1 1 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 GAN03740.1 - 1.2 9.2 5.4 4 7.5 2.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 GAN03740.1 - 1.4 8.8 4.5 2.7 7.9 4.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 GAN03740.1 - 1.4 9.2 7.1 2.6 8.3 7.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ASFV_J13L PF05568.11 GAN03740.1 - 2.3 7.9 6.8 6.1 6.6 0.4 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein Aph-1 PF06105.12 GAN03741.1 - 5.1e-34 117.7 11.8 5.8e-34 117.5 11.8 1.0 1 0 0 1 1 1 1 Aph-1 protein MscL PF01741.18 GAN03741.1 - 0.22 11.8 2.1 0.33 11.3 2.0 1.5 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL RRM_1 PF00076.22 GAN03742.1 - 2.8e-14 52.7 1.5 4.5e-11 42.4 0.4 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 GAN03742.1 - 0.00026 21.1 47.1 0.0057 16.7 10.2 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit RRM_occluded PF16842.5 GAN03742.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAN03742.1 - 0.055 13.5 0.8 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RIP PF00161.19 GAN03743.1 - 0.043 13.4 0.1 0.075 12.6 0.1 1.3 1 1 0 1 1 1 0 Ribosome inactivating protein Med13_C PF06333.12 GAN03744.1 - 8.5e-64 215.9 1.2 8.5e-64 215.9 1.2 5.6 5 1 0 6 6 6 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 GAN03744.1 - 1.9e-11 44.2 0.0 1.5e-09 38.0 0.0 6.5 5 2 1 6 6 6 2 MID domain of medPIWI B2-adapt-app_C PF09066.10 GAN03744.1 - 2 8.5 7.9 57 3.9 0.0 2.8 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain TMEM154 PF15102.6 GAN03745.1 - 0.00078 19.4 0.2 0.00078 19.4 0.2 1.7 2 0 0 2 2 2 1 TMEM154 protein family Peptidase_M56 PF05569.11 GAN03745.1 - 0.0042 16.3 2.7 0.0049 16.1 2.7 1.0 1 0 0 1 1 1 1 BlaR1 peptidase M56 Chordopox_A13L PF05961.11 GAN03745.1 - 0.0076 16.5 0.2 0.044 14.0 0.1 2.1 2 0 0 2 2 2 1 Chordopoxvirus A13L protein Glycophorin_A PF01102.18 GAN03745.1 - 0.015 15.5 0.6 0.024 14.9 0.6 1.3 1 0 0 1 1 1 0 Glycophorin A DUF5534 PF17686.1 GAN03745.1 - 0.015 15.5 1.1 0.022 15.0 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) PulG PF11773.8 GAN03745.1 - 0.016 15.0 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin TNFR_16_TM PF18422.1 GAN03745.1 - 0.019 14.9 1.5 0.036 14.0 1.5 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Rax2 PF12768.7 GAN03745.1 - 0.023 14.2 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity LapA_dom PF06305.11 GAN03745.1 - 0.026 14.4 0.4 0.05 13.4 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Orf78 PF06024.12 GAN03745.1 - 0.026 14.8 0.4 0.04 14.2 0.4 1.3 1 0 0 1 1 1 0 Orf78 (ac78) PRIMA1 PF16101.5 GAN03745.1 - 0.041 13.9 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CcmF_C PF16327.5 GAN03745.1 - 0.046 13.0 0.3 0.062 12.6 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal CD34_antigen PF06365.12 GAN03745.1 - 0.12 12.0 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Cadherin_C_2 PF16492.5 GAN03745.1 - 0.43 11.4 5.3 0.1 13.3 1.8 1.8 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Iso_dh PF00180.20 GAN03746.1 - 9.1e-102 340.7 0.1 1.1e-101 340.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Bromodomain PF00439.25 GAN03747.1 - 0.01 15.9 0.1 0.05 13.7 0.0 2.1 2 1 0 2 2 2 0 Bromodomain RRS1 PF04939.12 GAN03748.1 - 3.3e-55 186.4 3.0 3.3e-55 186.4 3.0 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Cyclin_N PF00134.23 GAN03749.1 - 6.7e-08 32.3 0.1 1.4e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN03749.1 - 1.5e-05 25.4 0.1 2.3e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin p450 PF00067.22 GAN03750.1 - 1.4e-61 208.7 0.1 1.4e-59 202.1 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 Arginosuc_synth PF00764.19 GAN03751.1 - 2.4e-152 507.7 0.0 2.8e-152 507.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 GAN03751.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAN03751.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase WD40 PF00400.32 GAN03752.1 - 5.5e-48 159.9 22.4 3.5e-09 37.1 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 GAN03752.1 - 1.2e-42 145.2 1.3 3.9e-42 143.6 0.9 2.1 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 GAN03752.1 - 5.5e-10 39.4 0.2 0.0075 16.5 0.0 4.7 2 1 2 5 5 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN03752.1 - 6.8e-05 22.3 0.2 0.11 11.8 0.0 3.4 3 1 1 4 4 4 2 WD40-like domain LisH PF08513.11 GAN03752.1 - 0.00018 21.3 0.4 0.0013 18.6 0.0 2.7 3 0 0 3 3 3 1 LisH Nup160 PF11715.8 GAN03752.1 - 0.001 17.8 10.3 0.094 11.3 0.0 4.4 3 2 0 5 5 5 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 GAN03752.1 - 0.19 10.9 3.9 58 2.8 0.0 4.0 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Presenilin PF01080.17 GAN03752.1 - 4.1 6.1 8.5 7.6 5.2 8.5 1.4 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 GAN03752.1 - 5.9 5.4 6.6 28 3.2 7.8 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF3295 PF11702.8 GAN03752.1 - 6.8 5.9 19.5 0.67 9.2 14.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) TFIIA PF03153.13 GAN03752.1 - 7 6.5 24.4 1.3 8.9 20.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L27A PF00828.19 GAN03753.1 - 5.2e-08 33.6 0.5 5.2e-08 33.6 0.5 1.8 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ank_2 PF12796.7 GAN03754.1 - 4.3e-10 40.1 0.1 8.4e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN03754.1 - 1.6e-08 34.9 0.1 4.3e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN03754.1 - 1.9e-06 27.7 0.9 1.4e-05 25.1 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAN03754.1 - 3.9e-06 27.0 0.2 1.4e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAN03754.1 - 0.00012 22.3 0.1 0.00028 21.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat DUF3306 PF11748.8 GAN03754.1 - 1.6 9.6 4.1 19 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RabGAP-TBC PF00566.18 GAN03755.1 - 2.5e-39 135.2 3.9 5e-39 134.2 3.9 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 GAN03755.1 - 9e-10 38.3 0.1 3.4e-09 36.4 0.1 1.9 1 1 1 2 2 2 1 Rab-binding domain (RBD) UPF0176_N PF17773.1 GAN03756.1 - 2.5e-18 66.2 0.0 5.4e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 GAN03756.1 - 6.9e-15 55.2 11.5 1.6e-14 54.0 11.5 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 GAN03756.1 - 1.8e-05 25.2 0.0 3.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 GAN03756.1 - 0.018 14.3 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ta0938 PF11494.8 GAN03756.1 - 0.8 10.0 3.3 1.7 9.0 3.3 1.5 1 0 0 1 1 1 0 Ta0938 Aa_trans PF01490.18 GAN03757.1 - 1.1e-93 314.2 39.6 1.3e-93 314.0 39.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4679 PF15728.5 GAN03757.1 - 0.028 13.5 10.3 0.054 12.5 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) OKR_DC_1_N PF03709.15 GAN03757.1 - 0.17 12.2 0.2 0.32 11.3 0.2 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF4699 PF15770.5 GAN03757.1 - 3.8 7.2 9.4 12 5.6 5.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4699) GST_C_3 PF14497.6 GAN03758.1 - 8.1e-19 67.7 0.1 1.4e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN03758.1 - 1.2e-07 31.8 0.0 2.8e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN03758.1 - 1.6e-06 28.0 0.0 4.1e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAN03758.1 - 0.0046 17.7 0.0 0.012 16.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 GAN03758.1 - 0.028 14.9 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAN03758.1 - 0.096 13.0 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 GAN03759.1 - 9.7e-26 90.5 19.6 1.6e-23 83.2 15.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN03759.1 - 9.1e-07 28.1 1.4 9.1e-07 28.1 1.4 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Sec20 PF03908.13 GAN03759.1 - 0.21 11.5 6.1 11 6.1 0.3 3.7 3 0 0 3 3 3 0 Sec20 DUF2148 PF09918.9 GAN03760.1 - 0.0048 16.9 0.5 0.0072 16.3 0.5 1.3 1 0 0 1 1 1 1 Uncharacterized protein containing a ferredoxin domain (DUF2148) Lipase_GDSL PF00657.22 GAN03761.1 - 7.9e-09 35.8 0.1 1.1e-08 35.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Homeodomain PF00046.29 GAN03762.1 - 2.5e-06 27.2 1.1 5.8e-06 26.1 1.1 1.6 1 0 0 1 1 1 1 Homeodomain CDC45 PF02724.14 GAN03762.1 - 0.025 12.9 3.9 0.037 12.3 3.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Homeobox_KN PF05920.11 GAN03762.1 - 0.043 13.7 0.5 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF3419 PF11899.8 GAN03763.1 - 1.1e-146 489.0 1.1 1.5e-146 488.5 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 GAN03763.1 - 1.7e-09 38.3 0.0 5.2e-08 33.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN03763.1 - 6.3e-09 35.9 0.0 3.5e-08 33.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN03763.1 - 8.9e-08 32.7 0.0 9.3e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN03763.1 - 1.8e-07 31.1 0.0 1.5e-06 28.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN03763.1 - 1.8e-06 28.6 0.0 7.9e-06 26.5 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN03763.1 - 2.2e-05 23.9 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAN03763.1 - 0.0022 17.3 0.0 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 GAN03763.1 - 0.015 14.7 0.0 0.062 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 GAN03763.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CBP PF12192.8 GAN03763.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal calcium binding protein Mad3_BUB1_I_2 PF17014.5 GAN03763.1 - 0.21 11.7 1.3 0.92 9.6 0.5 2.2 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein DHFR_1 PF00186.19 GAN03764.1 - 1e-36 126.0 0.0 7.1e-36 123.3 0.0 1.9 1 1 0 1 1 1 1 Dihydrofolate reductase CoaE PF01121.20 GAN03765.1 - 1.5e-60 203.9 0.1 2e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 GAN03765.1 - 8.4e-08 32.8 0.0 1.8e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAN03765.1 - 0.00014 22.2 0.0 0.00036 20.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF348 PF03990.14 GAN03765.1 - 0.023 14.4 0.1 0.087 12.6 0.1 2.0 1 1 0 1 1 1 0 G5-linked-Ubiquitin-like domain Bac_export_2 PF01312.19 GAN03765.1 - 0.067 12.4 0.3 4.8 6.3 0.1 2.3 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Ufd2P_core PF10408.9 GAN03766.1 - 2.6e-228 759.7 11.6 3.3e-228 759.4 11.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GAN03766.1 - 6.6e-25 87.1 2.2 1.2e-24 86.3 0.2 2.6 2 0 0 2 2 2 1 U-box domain MRP-L27 PF09809.9 GAN03767.1 - 1.8e-20 72.9 0.1 1.9e-20 72.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF4554 PF15091.6 GAN03767.1 - 0.21 10.4 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) ALMT PF11744.8 GAN03768.1 - 1.6e-18 66.8 17.0 2.4e-14 53.0 6.7 2.7 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC_2 PF13515.6 GAN03768.1 - 3.7e-14 52.9 12.0 3.7e-14 52.9 12.0 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 GAN03768.1 - 7.2e-13 48.4 13.5 6e-10 38.8 0.2 2.8 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 GAN03768.1 - 3.1e-10 40.3 2.7 3.1e-10 40.3 2.7 3.1 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 FUSC PF04632.12 GAN03768.1 - 2.1e-07 29.9 15.0 0.001 17.7 8.6 2.7 3 0 0 3 3 3 2 Fusaric acid resistance protein family SPT2 PF08243.11 GAN03768.1 - 1.9 9.0 7.9 3.8 8.1 7.9 1.5 1 0 0 1 1 1 0 SPT2 chromatin protein ArAE_1 PF06081.11 GAN03768.1 - 7.9 6.6 14.9 7 6.8 4.0 3.2 3 0 0 3 3 3 0 Aromatic acid exporter family member 1 AIM24 PF01987.17 GAN03769.1 - 2.9e-40 138.2 0.0 3.5e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Cullin_binding PF03556.15 GAN03770.1 - 1.3e-31 109.5 1.2 1.3e-31 109.5 1.2 1.8 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 GAN03770.1 - 1.5e-08 34.3 0.1 4e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.31 GAN03770.1 - 0.045 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain TAP_C PF03943.13 GAN03770.1 - 0.046 13.4 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 TAP C-terminal domain adh_short PF00106.25 GAN03771.1 - 2.3e-26 92.4 0.7 2.8e-25 88.9 0.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN03771.1 - 1e-12 48.1 0.1 7.7e-12 45.3 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN03771.1 - 3.2e-08 33.7 0.1 4.4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAN03771.1 - 0.00045 19.7 0.1 0.001 18.6 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAN03771.1 - 0.0034 16.9 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAN03771.1 - 0.0049 16.0 0.1 0.008 15.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THOC7 PF05615.13 GAN03772.1 - 1.3e-18 67.6 8.3 1.3e-18 67.6 8.3 2.5 1 1 1 2 2 2 1 Tho complex subunit 7 P22_Tail-4 PF11650.8 GAN03772.1 - 0.17 11.8 2.4 0.15 12.0 0.7 1.7 2 0 0 2 2 2 0 P22 tail accessory factor FPN1 PF06963.12 GAN03774.1 - 0.26 9.8 0.1 0.46 9.0 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) CCDC53 PF10152.9 GAN03774.1 - 4.3 7.7 7.1 1.7 9.1 1.3 2.3 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Gp58 PF07902.11 GAN03775.1 - 0.036 12.4 1.2 0.049 11.9 1.2 1.1 1 0 0 1 1 1 0 gp58-like protein LBP_BPI_CETP_C PF02886.17 GAN03775.1 - 0.036 13.5 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain Glyco_hydro_14 PF01373.17 GAN03775.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Nipped-B_C PF12830.7 GAN03777.1 - 2.7e-45 154.6 0.2 2.1e-44 151.7 0.1 2.6 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GAN03777.1 - 7e-06 26.2 3.7 2.2e-05 24.6 1.1 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 GAN03777.1 - 9.1e-06 25.5 2.0 1.7 9.1 0.1 6.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 GAN03777.1 - 0.02 15.3 1.1 0.14 12.5 0.3 2.7 2 0 0 2 2 2 0 HEAT repeats OSR1_C PF12202.8 GAN03777.1 - 1.5 9.1 6.7 0.36 11.1 0.3 2.9 3 0 0 3 3 3 0 Oxidative-stress-responsive kinase 1 C-terminal domain Mucin PF01456.17 GAN03777.1 - 7.4 6.6 15.5 0.13 12.3 7.2 2.2 3 0 0 3 3 3 0 Mucin-like glycoprotein IPK PF03770.16 GAN03778.1 - 9.3e-46 156.2 0.0 1.9e-44 151.9 0.0 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase DUF1015 PF06245.11 GAN03778.1 - 0.017 14.0 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) YodL PF14191.6 GAN03778.1 - 0.16 12.8 4.0 1.1 10.1 0.1 3.0 2 1 1 3 3 3 0 YodL-like DDE_3 PF13358.6 GAN03779.1 - 2.3e-10 40.4 0.2 2.9e-10 40.1 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 GAN03780.1 - 3.9e-16 59.2 0.0 2.4e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03780.1 - 8.8e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN03780.1 - 9.5e-05 21.3 0.5 0.00013 20.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Cu-oxidase_3 PF07732.15 GAN03781.1 - 2.1e-32 111.6 1.7 2.1e-32 111.6 1.7 2.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 GAN03781.1 - 4.3e-28 98.4 0.6 2e-27 96.2 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAN03781.1 - 5e-26 91.1 13.7 7.4e-25 87.3 0.5 4.1 3 1 0 3 3 3 2 Multicopper oxidase RPN13_C PF16550.5 GAN03782.1 - 1.2e-30 106.0 3.8 1.2e-30 106.0 3.8 1.8 2 0 0 2 2 2 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 GAN03782.1 - 6.7e-30 103.5 0.3 1.1e-29 102.7 0.3 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF1631 PF07793.11 GAN03782.1 - 0.022 13.2 15.2 0.014 13.9 8.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1631) CHAD PF05235.14 GAN03782.1 - 0.055 13.4 0.2 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 CHAD domain Mucin PF01456.17 GAN03782.1 - 0.085 12.8 10.8 0.14 12.2 10.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1400 PF07176.11 GAN03782.1 - 0.24 11.7 4.5 0.41 10.9 0.4 2.8 2 2 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) 2-oxoacid_dh PF00198.23 GAN03783.1 - 8.3e-75 251.2 0.1 1.2e-74 250.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAN03783.1 - 6.9e-17 61.1 0.0 1.6e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAN03783.1 - 2.4e-15 56.6 0.8 4.8e-15 55.6 0.8 1.6 1 0 0 1 1 1 1 e3 binding domain Asn_synthase PF00733.21 GAN03784.1 - 1.1e-51 176.5 0.2 1.5e-51 176.1 0.2 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 GAN03784.1 - 5.1e-32 110.4 0.2 2.3e-31 108.3 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAN03784.1 - 2.3e-22 79.6 0.0 4.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAN03784.1 - 0.004 16.6 0.0 0.017 14.5 0.0 2.2 2 1 0 2 2 2 1 Aluminium induced protein 7TM_GPCR_Srx PF10328.9 GAN03784.1 - 0.5 9.9 3.4 0.74 9.4 3.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF2427 PF10348.9 GAN03785.1 - 2.6 7.9 7.9 3.9 7.3 6.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) MFS_MOT1 PF16983.5 GAN03785.1 - 3.1 8.2 10.9 6.6 7.2 10.9 1.6 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily ArfGap PF01412.18 GAN03786.1 - 7.6e-33 113.1 1.5 7.6e-33 113.1 1.5 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ysc84 PF04366.12 GAN03787.1 - 3.5e-43 146.4 0.3 6.7e-43 145.5 0.3 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 GAN03787.1 - 9.7e-14 50.7 0.1 2.3e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAN03787.1 - 1.8e-12 46.9 0.0 3.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN03787.1 - 2.5e-10 39.9 0.0 5.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 GAN03787.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF4609 PF15382.6 GAN03787.1 - 0.15 12.0 1.1 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) Mito_carr PF00153.27 GAN03789.1 - 1.3e-43 146.8 0.6 1.2e-22 79.7 0.0 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein p450 PF00067.22 GAN03790.1 - 3e-51 174.6 0.9 6.3e-51 173.6 0.9 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF424 PF04242.13 GAN03790.1 - 0.04 14.2 0.2 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Abhydrolase_6 PF12697.7 GAN03791.1 - 1.5e-05 25.7 0.0 2.3e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN03791.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Sortilin-Vps10 PF15902.5 GAN03792.1 - 0 1346.6 18.5 1.3e-138 462.5 2.7 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 GAN03792.1 - 1.6e-128 425.6 33.8 1.6e-45 155.5 2.4 4.4 4 0 0 4 4 4 3 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 GAN03792.1 - 1.9e-05 24.0 73.7 2.1 8.7 0.1 16.3 16 0 0 16 16 16 6 BNR/Asp-box repeat PSII_BNR PF14870.6 GAN03792.1 - 4.2e-05 22.9 4.6 0.0018 17.6 0.1 5.3 6 0 0 6 6 6 1 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 GAN03792.1 - 0.00077 19.3 16.7 3.1 8.1 0.0 7.9 7 0 0 7 7 7 2 BNR-Asp box repeat Kelch_4 PF13418.6 GAN03793.1 - 8.2e-15 54.6 1.2 7.1e-06 25.9 0.1 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN03793.1 - 2.6e-11 43.4 2.6 0.002 18.3 0.1 4.6 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 GAN03793.1 - 3.1e-09 36.6 0.7 0.083 12.9 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAN03793.1 - 2.8e-08 33.8 0.3 0.21 11.9 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN03793.1 - 3.1e-06 26.6 0.8 0.0084 15.7 0.0 4.4 4 0 0 4 4 4 1 Kelch motif DUF4381 PF14316.6 GAN03793.1 - 0.083 13.1 0.2 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Kelch_2 PF07646.15 GAN03793.1 - 0.33 11.0 1.5 7.1 6.8 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Na_sulph_symp PF00939.19 GAN03794.1 - 1.7e-93 314.2 29.5 1.9e-93 314.0 29.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN03794.1 - 5.2e-15 55.4 32.0 2.9e-10 39.8 9.8 2.6 1 1 1 2 2 2 2 Citrate transporter AAA_5 PF07728.14 GAN03795.1 - 3.6e-129 425.4 0.5 5.1e-29 101.0 0.0 9.4 9 0 0 9 9 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 GAN03795.1 - 2.7e-54 181.8 2.4 2.1e-18 66.5 0.0 6.4 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 GAN03795.1 - 3.5e-35 120.3 0.3 4.9e-34 116.6 0.0 3.1 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 GAN03795.1 - 2.5e-33 114.7 0.0 6e-08 32.6 0.0 7.1 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 GAN03795.1 - 1.1e-28 100.2 0.1 0.0002 21.8 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAN03795.1 - 9.3e-27 93.7 3.8 8.9e-06 25.3 0.0 6.7 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 GAN03795.1 - 2.4e-25 89.8 7.6 0.00023 21.6 0.1 9.0 6 2 0 6 6 6 5 AAA ATPase domain AAA_22 PF13401.6 GAN03795.1 - 1.4e-21 77.2 5.0 8.8e-05 22.8 0.0 7.8 7 0 0 7 7 6 4 AAA domain Dynein_heavy PF03028.15 GAN03795.1 - 3.2e-20 72.4 0.1 0.0091 16.1 0.0 8.1 8 0 0 8 8 6 3 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 GAN03795.1 - 5.2e-20 72.3 11.1 0.0035 17.9 0.0 7.9 8 0 0 8 8 6 5 AAA domain Sigma54_activat PF00158.26 GAN03795.1 - 1.1e-19 70.7 0.1 0.0012 18.6 0.0 6.8 6 1 0 6 6 6 4 Sigma-54 interaction domain AAA_6 PF12774.7 GAN03795.1 - 1.6e-19 70.1 4.6 0.034 13.1 0.0 8.2 7 0 0 7 7 7 5 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 GAN03795.1 - 5.3e-18 65.3 0.0 0.0025 17.8 0.0 7.9 8 0 0 8 8 7 3 AAA domain AAA_30 PF13604.6 GAN03795.1 - 2.3e-17 63.4 0.0 0.0022 17.8 0.0 7.9 7 1 0 7 7 6 3 AAA domain ABC_tran PF00005.27 GAN03795.1 - 7.2e-17 62.2 0.5 0.004 17.7 0.0 8.1 6 0 0 6 6 6 2 ABC transporter TsaE PF02367.17 GAN03795.1 - 2.7e-15 56.5 4.5 0.16 11.9 0.0 6.7 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 GAN03795.1 - 8.8e-15 55.0 0.3 0.00011 22.3 0.0 5.9 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_33 PF13671.6 GAN03795.1 - 2.7e-14 53.5 1.2 1.2 9.3 0.0 7.2 6 0 0 6 6 6 2 AAA domain Zeta_toxin PF06414.12 GAN03795.1 - 8.9e-12 44.7 2.1 1.3 8.2 0.0 7.2 8 0 0 8 8 6 3 Zeta toxin AAA_28 PF13521.6 GAN03795.1 - 1.2e-11 45.2 2.9 0.75 10.0 0.0 6.9 6 0 0 6 6 6 1 AAA domain RsgA_GTPase PF03193.16 GAN03795.1 - 2.3e-11 43.9 2.6 0.94 9.4 0.0 6.6 6 0 0 6 6 6 2 RsgA GTPase AAA_25 PF13481.6 GAN03795.1 - 2.6e-10 40.2 0.8 0.48 10.0 0.0 5.9 5 0 0 5 5 5 2 AAA domain T2SSE PF00437.20 GAN03795.1 - 2.7e-10 39.8 2.4 0.98 8.4 0.0 6.2 6 0 0 6 6 6 2 Type II/IV secretion system protein RNA_helicase PF00910.22 GAN03795.1 - 6.7e-10 39.3 4.6 0.83 10.1 0.0 7.6 7 0 0 7 7 7 2 RNA helicase Rad17 PF03215.15 GAN03795.1 - 4.6e-09 36.5 0.7 0.71 9.8 0.0 5.9 5 0 0 5 5 5 2 Rad17 P-loop domain NACHT PF05729.12 GAN03795.1 - 7.4e-09 35.7 5.4 0.2 11.6 0.0 5.9 6 0 0 6 6 5 2 NACHT domain AAA_29 PF13555.6 GAN03795.1 - 9.1e-09 34.9 0.5 5.7 6.8 0.0 6.6 6 0 0 6 6 6 0 P-loop containing region of AAA domain RuvB_N PF05496.12 GAN03795.1 - 3.2e-08 33.5 0.2 0.64 9.8 0.0 6.8 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GAN03795.1 - 9.2e-08 31.7 4.5 0.15 11.4 0.0 8.2 8 1 0 8 8 8 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 GAN03795.1 - 3.8e-07 29.5 5.3 1.1 8.3 0.0 5.9 6 0 0 6 6 6 3 Protein of unknown function (DUF815) SRP54 PF00448.22 GAN03795.1 - 6.7e-07 29.1 3.7 0.33 10.5 0.1 5.0 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 GAN03795.1 - 9.6e-07 28.6 3.7 0.054 13.2 0.0 5.4 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 GAN03795.1 - 4.9e-06 26.4 0.3 1.8 8.3 0.0 5.4 6 0 0 6 6 5 1 IstB-like ATP binding protein TniB PF05621.11 GAN03795.1 - 6.3e-06 25.7 0.2 4.2 6.8 0.0 5.1 5 0 0 5 5 4 0 Bacterial TniB protein Roc PF08477.13 GAN03795.1 - 1e-05 25.7 2.2 13 6.1 0.0 6.5 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 GAN03795.1 - 2.1e-05 24.4 0.2 0.99 9.1 0.0 4.8 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 GAN03795.1 - 5.6e-05 22.8 4.2 9.6 5.7 0.1 6.4 7 0 0 7 7 6 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 GAN03795.1 - 6.8e-05 22.8 6.0 9.2 6.1 0.0 6.5 6 0 0 6 6 6 0 Deoxynucleoside kinase NTPase_1 PF03266.15 GAN03795.1 - 0.00038 20.4 4.1 3.6 7.5 0.1 5.4 5 0 0 5 5 4 0 NTPase MMR_HSR1 PF01926.23 GAN03795.1 - 0.0004 20.4 1.5 46 4.1 0.0 6.2 6 0 0 6 6 6 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 GAN03795.1 - 0.00072 19.3 2.3 3.5 7.3 0.0 5.1 5 0 0 5 5 4 0 Thymidylate kinase ResIII PF04851.15 GAN03795.1 - 0.00085 19.4 6.1 1.1 9.2 0.3 5.1 5 0 0 5 5 3 2 Type III restriction enzyme, res subunit CPT PF07931.12 GAN03795.1 - 0.0016 18.3 5.2 25 4.7 0.0 7.2 7 2 0 7 7 6 0 Chloramphenicol phosphotransferase-like protein VWA PF00092.28 GAN03795.1 - 0.0029 17.9 1.9 0.0063 16.8 0.4 2.5 2 0 0 2 2 1 1 von Willebrand factor type A domain MCM PF00493.23 GAN03795.1 - 0.0034 16.5 0.0 20 4.2 0.0 4.4 4 0 0 4 4 4 0 MCM P-loop domain ATPase PF06745.13 GAN03795.1 - 0.0043 16.4 0.2 9.2 5.5 0.0 4.2 4 0 0 4 4 4 0 KaiC PRK PF00485.18 GAN03795.1 - 0.0082 15.9 0.3 33 4.1 0.0 4.5 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 GAN03795.1 - 0.0086 15.8 0.0 6.6 6.3 0.0 4.0 4 1 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 GAN03795.1 - 0.014 15.1 0.0 33 4.1 0.0 4.2 4 0 0 4 4 3 0 Cytidylate kinase AAA_19 PF13245.6 GAN03795.1 - 0.021 15.2 21.2 0.19 12.1 0.6 6.9 7 2 0 7 7 6 0 AAA domain SKI PF01202.22 GAN03795.1 - 0.026 14.7 0.6 5.1 7.2 0.0 4.6 5 0 0 5 5 3 0 Shikimate kinase CbiA PF01656.23 GAN03795.1 - 0.083 12.9 0.6 28 4.8 0.0 4.5 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 GAN03795.1 - 0.1 12.3 18.6 1.3 8.7 0.1 6.6 8 0 0 8 8 6 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 GAN03795.1 - 0.12 12.3 0.0 85 3.0 0.0 3.5 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 IPT PF01745.16 GAN03795.1 - 0.33 10.3 3.9 12 5.2 0.0 4.7 5 0 0 5 5 3 0 Isopentenyl transferase AAA_21 PF13304.6 GAN03795.1 - 0.35 10.6 1.7 16 5.2 0.0 4.1 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 GAN03795.1 - 3.6 7.5 6.2 52 3.7 0.0 4.8 6 0 0 6 6 4 0 Molybdopterin guanine dinucleotide synthesis protein B Uso1_p115_head PF04869.14 GAN03796.1 - 4e-81 272.6 0.0 8.4e-81 271.5 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 GAN03796.1 - 5e-07 29.6 0.1 1.5e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 GAN03796.1 - 0.00024 21.5 23.3 0.0005 20.4 23.3 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region FPP PF05911.11 GAN03796.1 - 0.00043 18.6 10.4 0.00074 17.8 10.4 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 GAN03796.1 - 0.0064 15.2 11.3 0.0092 14.7 11.3 1.1 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.9 GAN03796.1 - 0.0071 16.4 14.5 0.0071 16.4 14.5 2.2 3 0 0 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RTP1_C1 PF10363.9 GAN03796.1 - 0.0097 16.1 0.2 2.3 8.4 0.0 3.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3584 PF12128.8 GAN03796.1 - 0.011 13.3 17.2 0.017 12.6 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.11 GAN03796.1 - 0.13 12.8 7.6 2.7 8.6 7.4 2.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF16 PF01519.16 GAN03796.1 - 0.32 11.5 9.7 0.062 13.8 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 GAN03796.1 - 0.41 8.5 7.5 0.63 7.9 7.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 GAN03796.1 - 0.57 10.2 14.5 1.2 9.2 12.8 2.4 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 GAN03796.1 - 0.62 10.2 14.1 0.087 13.0 3.9 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 GAN03796.1 - 0.91 9.6 16.0 14 5.8 16.0 2.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 GAN03796.1 - 1.1 9.3 15.4 1.8 8.6 13.0 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 GAN03796.1 - 1.3 8.3 7.8 2.4 7.4 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 GAN03796.1 - 1.4 9.3 13.3 2.9 8.3 13.3 1.4 1 0 0 1 1 1 0 Fez1 BLOC1_2 PF10046.9 GAN03796.1 - 1.5 9.1 12.9 0.63 10.4 2.8 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRAF_BIRC3_bd PF16673.5 GAN03796.1 - 1.8 8.4 5.3 0.4 10.5 0.5 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain SKA1 PF07160.12 GAN03796.1 - 2.5 7.9 9.6 5.5 6.8 9.6 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 GAN03796.1 - 2.7 8.0 5.2 3.9 7.5 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PIN_12 PF16289.5 GAN03796.1 - 3.4 8.1 11.1 16 6.0 10.9 2.3 1 1 1 2 2 2 0 PIN domain CLZ PF16526.5 GAN03796.1 - 3.8 7.9 11.5 2 8.8 1.7 3.5 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 GAN03796.1 - 5 6.1 10.3 10 5.1 10.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 GAN03796.1 - 5.8 7.6 15.5 1.1 9.9 1.2 4.0 3 1 1 4 4 3 0 SlyX LPP PF04728.13 GAN03796.1 - 6.1 7.3 11.7 1.7e+02 2.7 11.2 2.9 1 1 0 1 1 1 0 Lipoprotein leucine-zipper CSN5_C PF18323.1 GAN03796.1 - 6.2 7.8 9.0 12 6.9 3.5 2.5 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Arrestin_C PF02752.22 GAN03797.1 - 3e-08 34.2 0.2 9.7e-08 32.5 0.2 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 GAN03797.1 - 0.00023 20.5 0.7 0.27 10.4 0.2 2.4 1 1 1 2 2 2 2 Rgp1 Arrestin_C PF02752.22 GAN03798.1 - 4.5e-10 40.1 0.0 1.8e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 GAN03798.1 - 2.6e-05 23.6 0.9 0.00025 20.3 0.0 2.1 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 GAN03798.1 - 0.00012 22.2 0.1 0.0023 18.0 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Cwf_Cwc_15 PF04889.12 GAN03799.1 - 3.6e-80 269.3 27.3 4e-80 269.1 27.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GAN03799.1 - 2.1 6.5 28.7 2.3 6.3 28.7 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GAN03799.1 - 4.3 6.0 11.0 4.8 5.8 11.0 1.2 1 0 0 1 1 1 0 Presenilin PTPLA PF04387.14 GAN03800.1 - 4e-53 179.5 15.7 6.8e-53 178.8 15.7 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CUE PF02845.16 GAN03801.1 - 6.1e-10 38.6 0.0 1.5e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 CUE domain ABC2_membrane PF01061.24 GAN03802.1 - 7.1e-86 286.9 53.5 1e-45 155.7 22.0 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAN03802.1 - 1.1e-34 119.9 0.0 2.2e-21 76.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAN03802.1 - 4.2e-29 100.3 16.2 5e-24 84.0 0.3 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 GAN03802.1 - 1.2e-10 41.1 52.1 1.2e-05 24.6 16.5 3.4 2 2 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 GAN03802.1 - 1.6e-10 41.5 0.1 3.9e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 GAN03802.1 - 1.9e-05 24.7 0.0 0.06 13.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAN03802.1 - 0.00012 22.6 0.0 0.025 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAN03802.1 - 0.00062 19.8 3.0 0.13 12.3 0.1 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAN03802.1 - 0.0021 18.5 0.0 0.013 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_2 PF12679.7 GAN03802.1 - 0.0029 17.0 16.3 0.0056 16.0 0.6 2.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 GAN03802.1 - 0.0038 17.0 1.2 0.058 13.1 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAN03802.1 - 0.0044 16.9 0.5 0.014 15.3 0.2 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 GAN03802.1 - 0.0048 17.1 0.1 0.093 12.9 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAN03802.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAN03802.1 - 0.035 14.3 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAN03802.1 - 0.15 12.4 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAN03802.1 - 0.19 11.5 0.5 3 7.6 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pro_isomerase PF00160.21 GAN03804.1 - 9.1e-41 139.8 0.0 1.6e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 GAN03804.1 - 2.6e-17 62.4 0.0 5.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MLANA PF14991.6 GAN03805.1 - 0.022 15.0 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A Ferlin_C PF16165.5 GAN03805.1 - 1.9 8.4 3.2 2.7 7.9 2.3 1.6 1 1 0 1 1 1 0 Ferlin C-terminus Pkinase PF00069.25 GAN03806.1 - 6.4e-58 196.2 0.0 7.6e-57 192.7 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain NAS PF03059.16 GAN03806.1 - 8.9e-53 179.4 1.0 1.4e-52 178.8 1.0 1.3 1 0 0 1 1 1 1 Nicotianamine synthase protein Pkinase_Tyr PF07714.17 GAN03806.1 - 9e-28 97.3 0.0 2.3e-27 95.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Methyltransf_31 PF13847.6 GAN03806.1 - 2.8e-06 27.2 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Kinase-like PF14531.6 GAN03806.1 - 0.001 18.5 0.1 0.0042 16.5 0.1 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAN03806.1 - 0.0022 17.9 0.6 0.0037 17.2 0.6 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN03806.1 - 0.0031 16.9 1.7 0.0062 15.9 1.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAN03806.1 - 0.82 8.4 7.0 0.056 12.2 0.3 2.0 2 0 0 2 2 2 0 Fungal protein kinase ATP-synt_10 PF05176.14 GAN03807.1 - 2.5e-53 181.0 0.5 2.9e-53 180.7 0.5 1.1 1 0 0 1 1 1 1 ATP10 protein Redoxin PF08534.10 GAN03807.1 - 0.0079 15.9 0.1 0.023 14.4 0.1 1.7 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAN03807.1 - 0.015 15.3 0.2 0.22 11.4 0.2 2.5 2 1 0 2 2 2 0 AhpC/TSA family DUF4512 PF14975.6 GAN03807.1 - 0.12 13.2 0.1 0.31 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) TMF_TATA_bd PF12325.8 GAN03808.1 - 1.8e-32 112.0 16.8 1.8e-32 112.0 16.8 8.6 3 1 2 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 GAN03808.1 - 3.6e-14 52.5 16.7 3.6e-14 52.5 16.7 11.9 5 2 6 11 11 11 2 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 GAN03808.1 - 0.0052 16.8 7.5 0.0052 16.8 7.5 8.0 3 2 5 8 8 8 4 Protein of unknown function (DUF1664) ATG16 PF08614.11 GAN03808.1 - 0.0093 16.2 20.6 0.0093 16.2 20.6 6.7 1 1 4 6 6 6 3 Autophagy protein 16 (ATG16) DUF3800 PF12686.7 GAN03808.1 - 0.41 11.3 6.2 8.2e+02 0.6 6.1 4.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) ADK PF00406.22 GAN03809.1 - 9.8e-47 158.8 0.0 1.4e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAN03809.1 - 5.4e-37 127.3 1.1 1.5e-36 125.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAN03809.1 - 3.8e-11 43.6 0.0 6.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN03809.1 - 4.9e-07 30.0 0.0 1.5e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAN03809.1 - 5.6e-05 22.9 1.0 0.088 12.5 0.2 2.4 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 GAN03809.1 - 0.00042 19.7 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 GAN03809.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 GAN03809.1 - 0.21 11.8 0.7 0.37 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain EF-1_beta_acid PF10587.9 GAN03809.1 - 0.25 11.8 5.1 0.71 10.4 5.1 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DnaJ_C PF01556.18 GAN03810.1 - 6.9e-40 136.5 0.5 9.2e-40 136.1 0.5 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN03810.1 - 3.4e-27 94.3 1.6 5.7e-27 93.6 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 GAN03810.1 - 0.0019 18.1 0.5 0.0053 16.6 0.2 1.9 2 0 0 2 2 2 1 A repeated domain in UCH-protein ACOX PF01756.19 GAN03812.1 - 5.5e-37 127.1 1.0 3.4e-36 124.5 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAN03812.1 - 2.6e-21 76.4 0.6 5.3e-21 75.5 0.6 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAN03812.1 - 5e-10 39.5 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAN03812.1 - 7.3e-05 23.0 0.0 0.0013 19.0 0.0 2.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MBOAT PF03062.19 GAN03813.1 - 6.6e-21 75.0 15.4 8.8e-21 74.6 15.4 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1674 PF07896.12 GAN03814.1 - 6.2e-20 71.4 1.9 1e-19 70.8 1.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Spo7 PF03907.13 GAN03815.1 - 3.7e-26 92.0 8.7 2e-23 83.0 2.7 2.0 1 1 1 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.9 GAN03815.1 - 0.00033 21.0 0.1 0.00044 20.6 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 188 Apolipoprotein PF01442.18 GAN03816.1 - 7.2e-07 29.3 28.4 1.2e-05 25.2 28.3 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DOT1 PF08123.13 GAN03816.1 - 0.0047 16.5 5.2 1.1 8.7 0.3 3.1 1 1 1 3 3 3 2 Histone methylation protein DOT1 YtxH PF12732.7 GAN03816.1 - 0.0066 17.0 44.5 1.6e+02 2.9 19.0 4.8 1 1 1 2 2 2 0 YtxH-like protein Prominin PF05478.11 GAN03816.1 - 0.011 13.8 8.9 0.013 13.5 8.9 1.0 1 0 0 1 1 1 0 Prominin Chlorosome_CsmC PF11098.8 GAN03816.1 - 0.013 15.5 2.6 0.013 15.5 2.6 3.5 2 1 1 3 3 3 0 Chlorosome envelope protein C DUF883 PF05957.13 GAN03816.1 - 0.018 15.6 32.3 0.21 12.2 4.7 4.6 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) CC2-LZ PF16516.5 GAN03816.1 - 0.03 14.7 21.5 0.22 11.9 3.9 3.6 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ApoO PF09769.9 GAN03816.1 - 0.074 13.0 15.6 2.1 8.3 0.6 4.2 1 1 2 4 4 4 0 Apolipoprotein O Mitofilin PF09731.9 GAN03816.1 - 0.2 10.5 36.5 0.25 10.1 36.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein IGR PF09597.10 GAN03816.1 - 0.38 10.9 2.0 97 3.2 0.1 3.8 4 0 0 4 4 4 0 IGR protein motif LEA_4 PF02987.16 GAN03816.1 - 0.7 10.0 46.2 1.2 9.2 0.9 5.9 4 2 0 5 5 5 0 Late embryogenesis abundant protein DUF948 PF06103.11 GAN03816.1 - 2.6 8.4 25.9 3.8 7.8 1.7 4.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 GAN03816.1 - 4.3 6.8 18.7 16 4.9 18.7 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit CdvA PF18822.1 GAN03816.1 - 5.3 6.9 26.6 1.7 8.5 1.6 4.5 2 1 3 5 5 5 0 CdvA-like coiled-coil domain PRKCSH-like PF12999.7 GAN03816.1 - 9.3 6.0 24.0 1.4 8.7 3.2 3.8 2 1 2 4 4 4 0 Glucosidase II beta subunit-like PDCD2_C PF04194.13 GAN03817.1 - 5.8e-42 143.7 7.2 1.9e-40 138.8 0.3 3.1 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain Ada3 PF10198.9 GAN03817.1 - 0.087 13.0 3.1 0.19 11.9 3.1 1.5 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 YqzE PF14038.6 GAN03817.1 - 2.6 8.1 5.7 8.8 6.4 5.7 1.9 1 0 0 1 1 1 0 YqzE-like protein CotH PF08757.11 GAN03818.1 - 1.4e-40 139.8 4.2 2.3e-40 139.1 4.2 1.2 1 0 0 1 1 1 1 CotH kinase protein NAP PF00956.18 GAN03818.1 - 0.11 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) NAD_kinase PF01513.21 GAN03819.1 - 1.3e-73 247.7 0.0 6e-72 242.3 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAN03819.1 - 0.12 11.9 0.0 0.54 9.9 0.0 2.1 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Androgen_recep PF02166.16 GAN03820.1 - 0.24 10.2 0.0 0.24 10.2 0.0 2.0 1 1 1 2 2 2 0 Androgen receptor Hemocyanin_C PF03723.14 GAN03821.1 - 0.068 12.5 0.2 0.11 11.8 0.2 1.4 1 1 0 1 1 1 0 Hemocyanin, ig-like domain RhoGEF PF00621.20 GAN03822.1 - 0.0053 17.0 0.3 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain Glyco_hydro_17 PF00332.18 GAN03823.1 - 4.4e-12 46.2 7.7 7e-07 29.1 1.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 GPI-anchored PF10342.9 GAN03824.1 - 0.019 15.7 0.1 0.032 15.0 0.1 1.4 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SPAN PF02510.14 GAN03824.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein RGS PF00615.19 GAN03825.1 - 2.3e-13 50.5 2.6 6.2e-13 49.1 2.6 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain Imm74 PF15603.6 GAN03826.1 - 1.9 8.8 8.6 0.12 12.6 0.8 3.1 2 1 1 3 3 3 0 Immunity protein 74 CoA_transf_3 PF02515.17 GAN03827.1 - 7.2e-98 328.1 0.0 1.2e-97 327.4 0.0 1.3 1 1 1 2 2 2 1 CoA-transferase family III TLD PF07534.16 GAN03828.1 - 7.1e-40 136.4 0.0 8.2e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 TLD G6PD_C PF02781.16 GAN03829.1 - 4.4e-112 374.0 0.1 1.2e-111 372.6 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAN03829.1 - 7.6e-61 205.8 0.1 3e-60 203.9 0.1 2.0 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3450 PF11932.8 GAN03830.1 - 0.018 14.4 0.2 0.018 14.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Glycos_transf_1 PF00534.20 GAN03831.1 - 2.6e-20 72.7 0.0 6.3e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN03831.1 - 1.2e-12 48.4 0.0 4e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAN03831.1 - 7.8e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_25 PF13649.6 GAN03832.1 - 1.8e-16 60.6 0.0 3.8e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN03832.1 - 4.2e-16 59.2 0.0 6.9e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN03832.1 - 2.1e-13 50.3 0.0 1.7e-12 47.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN03832.1 - 1.7e-12 47.8 0.0 3.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN03832.1 - 2e-10 41.3 0.0 5.5e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN03832.1 - 3.3e-06 26.7 0.0 5.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 GAN03832.1 - 2.8e-05 23.6 0.0 6.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 GAN03832.1 - 0.00031 19.4 0.0 0.00054 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 GAN03832.1 - 0.003 17.1 0.0 0.009 15.5 0.0 1.7 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 GAN03832.1 - 0.031 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain NPL4 PF05021.15 GAN03833.1 - 9.4e-125 416.0 0.1 1.2e-124 415.7 0.1 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 GAN03833.1 - 3.3e-69 231.6 0.5 3.3e-69 231.6 0.5 1.8 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 GAN03833.1 - 1.6e-11 44.5 0.0 3.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 TRCF PF03461.15 GAN03833.1 - 0.034 14.5 0.1 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 TRCF domain Sec7 PF01369.20 GAN03834.1 - 1.3e-32 112.9 0.1 3.4e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 GAN03834.1 - 2.9e-32 111.5 1.7 6e-31 107.3 0.2 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAN03834.1 - 8.3e-06 26.3 0.0 0.0024 18.3 0.0 3.2 2 1 1 3 3 3 1 PH domain YCII PF03795.14 GAN03834.1 - 0.13 12.7 0.0 0.86 10.0 0.0 2.2 2 0 0 2 2 2 0 YCII-related domain baeRF_family10 PF18854.1 GAN03835.1 - 0.062 13.5 5.5 0.048 13.9 1.2 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF1722 PF08349.11 GAN03835.1 - 0.83 10.0 7.7 0.32 11.3 0.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) dCache_2 PF08269.11 GAN03835.1 - 6.6 5.8 13.6 1.1 8.4 4.4 2.4 2 0 0 2 2 2 0 Cache domain COX5B PF01215.19 GAN03836.1 - 1.8e-45 153.7 0.0 2.2e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 GAN03836.1 - 0.0061 16.6 0.3 0.012 15.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger domain zf-C4_Topoisom PF01396.19 GAN03836.1 - 0.014 15.1 0.6 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_5 PF13719.6 GAN03836.1 - 0.06 13.1 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain COG6 PF06419.11 GAN03836.1 - 0.13 10.4 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 zf-C2H2_4 PF13894.6 GAN03837.1 - 0.001 19.7 3.2 0.48 11.4 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAN03837.1 - 0.032 14.6 0.8 0.032 14.6 0.8 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 GAN03837.1 - 0.34 11.5 5.6 0.38 11.3 0.0 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type CorA PF01544.18 GAN03838.1 - 2.9e-39 135.1 1.2 7.5e-39 133.8 1.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein RIC1 PF07064.13 GAN03839.1 - 3.2e-85 285.6 0.0 1e-84 283.9 0.0 1.9 2 1 0 2 2 2 1 RIC1 ANAPC4_WD40 PF12894.7 GAN03839.1 - 8.3e-05 22.8 0.2 0.022 15.0 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN03839.1 - 0.11 11.8 0.7 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Presenilin PF01080.17 GAN03842.1 - 0.022 13.5 0.3 0.07 11.9 0.1 1.8 2 0 0 2 2 2 0 Presenilin Ras PF00071.22 GAN03843.1 - 3.9e-23 81.8 0.0 4.8e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN03843.1 - 1.6e-12 47.7 0.2 2.2e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN03843.1 - 0.018 14.5 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family ILVD_EDD PF00920.21 GAN03844.1 - 7.4e-214 711.1 0.5 8.5e-214 710.9 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Asp PF00026.23 GAN03845.1 - 4.5e-69 233.3 5.5 5.4e-68 229.7 5.5 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN03845.1 - 2.4e-10 41.0 7.9 3.5e-09 37.2 1.6 4.1 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN03845.1 - 0.011 16.4 1.0 0.61 10.8 0.1 3.3 3 0 0 3 3 3 0 Aspartyl protease zf-C2H2 PF00096.26 GAN03846.1 - 1.6e-07 31.3 19.3 0.00069 19.9 4.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN03846.1 - 0.0008 19.7 4.2 0.0008 19.7 4.2 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAN03846.1 - 0.0016 18.7 1.0 0.0016 18.7 1.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 GAN03846.1 - 0.0031 17.8 3.9 0.0091 16.3 3.9 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 GAN03846.1 - 0.0041 17.8 3.7 0.0041 17.8 3.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 GAN03846.1 - 0.063 13.9 0.1 0.063 13.9 0.1 3.7 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 GAN03846.1 - 0.18 12.3 3.5 0.4 11.1 1.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAN03846.1 - 1.9 8.6 10.8 0.04 13.9 3.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger AMP-binding PF00501.28 GAN03847.1 - 2.1e-73 247.4 0.0 2.5e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN03847.1 - 1.2e-10 42.2 0.0 2.7e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Asparaginase_2 PF01112.18 GAN03848.1 - 1.4e-40 139.2 2.9 1.6e-39 135.7 2.9 1.9 1 1 0 1 1 1 1 Asparaginase Tetraspanin PF00335.20 GAN03849.1 - 0.051 13.3 14.1 0.1 12.3 8.9 2.8 1 1 1 2 2 2 0 Tetraspanin family DUF3951 PF13131.6 GAN03849.1 - 0.056 13.6 0.5 0.056 13.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Choline_transpo PF04515.12 GAN03849.1 - 0.057 12.6 11.4 0.48 9.6 11.4 2.0 2 0 0 2 2 2 0 Plasma-membrane choline transporter Baculo_ODV-E27 PF05314.11 GAN03849.1 - 0.081 12.1 1.1 0.13 11.4 0.3 1.7 2 0 0 2 2 2 0 Baculovirus occlusion-derived virus envelope protein EC27 DUF4064 PF13273.6 GAN03849.1 - 0.62 10.4 8.0 6.5 7.1 5.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) 7tm_1 PF00001.21 GAN03849.1 - 0.75 9.1 9.2 1.2 8.5 9.2 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1700 PF08006.11 GAN03849.1 - 1.6 8.3 10.4 2.8 7.4 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Lig_chan PF00060.26 GAN03849.1 - 1.6 8.5 4.3 2 8.2 3.8 1.3 1 1 0 1 1 1 0 Ligand-gated ion channel DUF373 PF04123.13 GAN03849.1 - 2.4 7.5 9.3 1.8 8.0 7.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF1422 PF07226.11 GAN03849.1 - 9 6.4 12.5 3.4e+03 -2.0 12.5 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1422) Ank_2 PF12796.7 GAN03850.1 - 6.3e-27 94.0 1.8 5.4e-10 39.7 0.2 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN03850.1 - 3.4e-21 75.3 5.5 1.4e-07 31.9 0.1 6.2 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN03850.1 - 2e-12 46.1 6.7 0.0002 21.6 0.0 7.1 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 GAN03850.1 - 7.3e-12 45.3 0.9 0.0098 16.2 0.0 5.4 2 2 5 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 GAN03850.1 - 7.6e-09 35.6 7.8 0.059 13.8 0.1 6.0 6 0 0 6 6 6 3 Ankyrin repeat Sox17_18_mid PF12067.8 GAN03850.1 - 0.13 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Sox 17/18 central domain DUF2061 PF09834.9 GAN03850.1 - 0.19 12.3 0.0 0.56 10.7 0.0 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) Longin PF13774.6 GAN03851.1 - 1.1e-23 83.0 0.0 1.8e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAN03851.1 - 3.8e-20 71.5 0.8 6.5e-20 70.7 0.8 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF4073 PF13285.6 GAN03851.1 - 0.063 12.9 1.1 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) DUF16 PF01519.16 GAN03851.1 - 0.13 12.7 3.6 0.11 13.0 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Peptidase_S8 PF00082.22 GAN03852.1 - 1.3e-34 119.9 5.7 1.3e-34 119.9 5.7 1.6 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 GAN03852.1 - 2e-16 60.4 0.6 3.5e-16 59.6 0.6 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3757 PF12582.8 GAN03852.1 - 0.15 12.4 0.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3757) Retrotrans_gag PF03732.17 GAN03853.1 - 7.3e-09 35.8 0.1 2.4e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 GAN03853.1 - 4.6e-08 32.9 0.0 8.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) RT_RNaseH PF17917.1 GAN03854.1 - 2.7e-36 124.0 0.2 1.7e-35 121.4 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN03854.1 - 7.1e-34 115.8 0.0 2.3e-33 114.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAN03854.1 - 2.9e-22 79.3 0.1 6.3e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAN03854.1 - 1.9e-18 66.3 0.1 7.3e-18 64.4 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GAN03854.1 - 5.2e-16 58.9 0.0 1.8e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 GAN03854.1 - 2.4e-14 52.9 2.7 2.4e-14 52.9 2.7 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 GAN03854.1 - 2.1e-05 24.3 0.3 5.2e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 GAN03854.1 - 0.003 17.7 0.2 0.008 16.4 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger DUF3221 PF11518.8 GAN03854.1 - 0.0087 16.4 0.5 0.025 14.9 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3221) Asp_protease_2 PF13650.6 GAN03854.1 - 0.021 15.5 0.0 0.068 13.8 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 GAN03854.1 - 0.036 14.6 0.0 0.11 13.1 0.0 1.8 2 0 0 2 2 1 0 gag-polyprotein putative aspartyl protease Ank_2 PF12796.7 GAN03855.1 - 5.8e-18 65.3 1.1 1.2e-09 38.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAN03855.1 - 2.6e-10 40.2 1.1 1.8e-05 25.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat TIG PF01833.24 GAN03855.1 - 1.1e-09 38.2 0.1 2.9e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_5 PF13857.6 GAN03855.1 - 4.3e-08 33.3 0.2 8.5e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN03855.1 - 4e-07 30.4 0.2 2.3e-06 28.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN03855.1 - 3.2e-06 27.1 0.2 0.054 14.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat SRP40_C PF05022.12 GAN03856.1 - 1.8e-27 96.0 2.2 1.8e-27 96.0 2.2 2.9 2 0 0 2 2 2 1 SRP40, C-terminal domain LisH PF08513.11 GAN03856.1 - 0.022 14.7 0.2 0.043 13.8 0.2 1.5 1 0 0 1 1 1 0 LisH zf-CCCH_4 PF18044.1 GAN03857.1 - 1.4e-12 47.1 12.5 1.8e-06 27.6 1.0 2.8 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAN03857.1 - 2.7e-09 36.8 24.5 2.3e-06 27.5 4.5 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 GAN03857.1 - 2.1e-08 33.8 13.0 9.2e-06 25.4 2.0 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAN03857.1 - 9e-05 23.1 17.4 0.0021 18.7 0.8 3.1 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 GAN03857.1 - 0.0002 21.5 3.4 0.0002 21.5 3.4 1.9 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 GAN03857.1 - 0.039 14.4 2.7 0.039 14.4 2.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger IATP PF04568.12 GAN03857.1 - 3.6 8.1 5.1 15 6.1 0.2 3.2 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Disintegrin PF00200.23 GAN03857.1 - 4.6 8.1 6.2 11 6.8 6.2 1.7 1 1 0 1 1 1 0 Disintegrin Chromo_shadow PF01393.19 GAN03858.1 - 6.2e-15 55.0 4.1 4e-12 46.0 0.6 2.6 2 1 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 GAN03858.1 - 1.5e-09 37.6 1.6 1.5e-09 37.6 1.6 2.6 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain IMPa_helical PF18642.1 GAN03858.1 - 0.036 14.5 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain Tudor-knot PF11717.8 GAN03858.1 - 0.077 12.9 1.6 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Ribosomal_L28 PF00830.19 GAN03859.1 - 4.6e-21 74.8 0.5 4.6e-21 74.8 0.5 1.5 2 0 0 2 2 2 1 Ribosomal L28 family zf-AN1 PF01428.16 GAN03860.1 - 1.5e-22 79.4 26.3 8e-13 48.3 4.0 3.2 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 GAN03860.1 - 0.001 19.4 17.7 0.0087 16.4 2.4 2.8 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.21 GAN03860.1 - 0.077 13.2 22.1 2.6 8.4 13.9 3.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC PF07967.13 GAN03860.1 - 3.3 7.8 11.9 1.9 8.5 0.5 2.7 1 1 2 3 3 3 0 C3HC zinc finger-like Cation_efflux PF01545.21 GAN03861.1 - 3e-10 40.2 7.8 4.6e-10 39.5 7.8 1.3 1 0 0 1 1 1 1 Cation efflux family YrvL PF14184.6 GAN03861.1 - 1.2 9.2 10.6 0.1 12.7 0.5 3.0 3 0 0 3 3 3 0 Regulatory protein YrvL CYSTM PF12734.7 GAN03864.1 - 2.3e-06 27.8 30.7 2.3e-06 27.8 30.7 4.2 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance DUF2477 PF10631.9 GAN03864.1 - 0.68 10.6 9.1 0.83 10.3 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DUF2076 PF09849.9 GAN03864.1 - 7.9 6.4 19.6 10 6.1 19.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pox_MCEL PF03291.16 GAN03865.1 - 6e-87 291.9 0.1 1.1e-86 291.0 0.1 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 GAN03865.1 - 4.2e-13 49.8 0.0 1.2e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN03865.1 - 5.4e-07 29.5 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN03865.1 - 8.2e-07 29.6 0.0 2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN03865.1 - 5.3e-06 26.4 0.0 7.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN03865.1 - 5.8e-06 27.0 0.0 1.6e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN03865.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 GAN03865.1 - 0.0027 16.9 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MetW PF07021.12 GAN03865.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PrmA PF06325.13 GAN03865.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 GAN03865.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 GAN03865.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 GAN03866.1 - 1e-111 373.4 0.0 1.2e-111 373.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN03866.1 - 6.6e-13 49.3 1.4 9.4e-11 42.3 0.5 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN03866.1 - 0.0015 18.3 0.0 0.0049 16.6 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAN03866.1 - 0.0016 19.1 0.0 1 10.1 0.0 3.0 3 1 0 3 3 3 2 Aspartyl protease DUF2433 PF10360.9 GAN03867.1 - 1.2e-45 154.6 1.1 2.2e-45 153.8 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 GAN03867.1 - 3.1e-08 33.3 0.0 5.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2407_C PF13373.6 GAN03868.1 - 4.9e-15 55.9 3.2 7.5e-14 52.1 3.2 2.2 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 GAN03868.1 - 6.1e-07 30.0 1.6 3.9e-06 27.4 0.4 2.1 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAN03868.1 - 2.1e-06 27.4 0.1 3.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family VHS PF00790.19 GAN03869.1 - 7.1e-41 139.4 0.1 2.4e-40 137.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 GAN03869.1 - 3.7e-24 85.2 1.0 3.7e-24 85.2 1.0 2.4 3 0 0 3 3 3 1 Adaptin C-terminal domain GAT PF03127.14 GAN03869.1 - 9.5e-15 54.7 0.3 4.3e-14 52.6 0.3 2.2 1 0 0 1 1 1 1 GAT domain GGA_N-GAT PF18308.1 GAN03869.1 - 4.8e-05 22.9 0.1 4.8e-05 22.9 0.1 2.6 3 0 0 3 3 3 1 GGA N-GAT domain Luteo_P1-P2 PF08467.10 GAN03869.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase DUF4404 PF14357.6 GAN03869.1 - 0.075 13.7 0.1 0.26 12.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Pkinase PF00069.25 GAN03870.1 - 1.9e-27 96.3 0.0 2.8e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03870.1 - 3e-15 56.2 0.0 4.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN03870.1 - 3.7e-10 39.2 1.5 4.9e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAN03870.1 - 0.00074 19.5 0.0 0.0064 16.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAN03870.1 - 0.025 13.6 0.1 0.036 13.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kei1 PF08552.11 GAN03870.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Androgen_recep PF02166.16 GAN03870.1 - 0.3 9.9 7.1 0.42 9.4 7.1 1.1 1 0 0 1 1 1 0 Androgen receptor RRM_1 PF00076.22 GAN03871.1 - 5.7e-08 32.5 0.6 1.4e-07 31.2 0.2 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN03871.1 - 0.098 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.28 GAN03873.1 - 6.2e-102 341.3 0.0 8e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN03873.1 - 1.9e-05 25.5 0.3 8.3e-05 23.5 0.3 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Atx10homo_assoc PF09759.9 GAN03874.1 - 2.8e-37 126.7 2.6 3.7e-36 123.1 0.3 2.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 GAN03874.1 - 2.1e-05 24.4 0.0 0.035 14.1 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat DTW PF03942.15 GAN03880.1 - 2.5e-29 102.4 0.0 4.1e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 DTW domain Fe_hyd_lg_C PF02906.14 GAN03881.1 - 4.8e-74 249.1 0.0 7.5e-72 241.9 0.0 2.3 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 GAN03881.1 - 9.8e-08 32.0 0.0 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit CENP-H PF05837.12 GAN03883.1 - 0.00071 20.0 8.8 0.00071 20.0 8.8 2.4 2 0 0 2 2 2 1 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 GAN03883.1 - 0.033 14.4 24.0 0.16 12.2 8.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF677 PF05055.12 GAN03883.1 - 0.044 12.7 12.4 0.07 12.0 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DUF5343 PF17278.2 GAN03883.1 - 0.051 13.7 4.5 0.22 11.6 0.7 2.5 1 1 2 3 3 3 0 Family of unknown function (DUF5343) NPV_P10 PF05531.12 GAN03883.1 - 0.078 13.4 9.2 0.26 11.8 2.6 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TFIIE_beta PF02186.15 GAN03883.1 - 0.14 12.5 5.3 0.11 12.8 1.8 2.3 2 0 0 2 2 2 0 TFIIE beta subunit core domain DUF3800 PF12686.7 GAN03883.1 - 0.44 11.2 2.6 1.5 9.5 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DivIC PF04977.15 GAN03883.1 - 0.57 10.0 23.5 0.072 12.9 3.7 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF2730 PF10805.8 GAN03883.1 - 0.59 10.2 11.3 1.2 9.3 4.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) YabA PF06156.13 GAN03883.1 - 1.4 9.6 22.1 0.6 10.8 6.8 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Phage_GP20 PF06810.11 GAN03883.1 - 2.7 7.8 23.2 2.9 7.7 8.5 2.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF16 PF01519.16 GAN03883.1 - 4.1 8.0 21.0 2.9 8.4 6.9 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 GAN03883.1 - 4.7 6.5 16.7 6.9 5.9 16.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EIAV_Rev PF11129.8 GAN03883.1 - 7 6.9 10.4 1.2 9.4 1.2 2.1 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus Sec2p PF06428.11 GAN03884.1 - 1.3e-13 50.7 10.7 2.4e-13 49.9 10.1 1.8 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 GAN03884.1 - 0.02 12.8 8.1 0.026 12.5 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 GAN03884.1 - 1.6 8.3 8.1 2.3 7.7 8.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Oxidored_FMN PF00724.20 GAN03885.1 - 5.8e-102 341.5 0.0 6.8e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family STb_secrete PF09075.10 GAN03885.1 - 0.096 12.8 0.0 24 5.1 0.0 2.5 2 0 0 2 2 2 0 Heat-stable enterotoxin B, secretory DHHC PF01529.20 GAN03886.1 - 6.4e-36 123.4 10.2 2.8e-35 121.4 8.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase RGS_DHEX PF18148.1 GAN03886.1 - 0.28 11.3 1.8 13 6.0 0.4 2.9 2 1 1 3 3 3 0 Regulator of G-protein signalling DHEX domain DUF2076 PF09849.9 GAN03887.1 - 8.3 6.4 13.2 10 6.1 13.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) eIF-1a PF01176.19 GAN03888.1 - 9.3e-10 38.2 0.3 1.8e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Translation initiation factor 1A / IF-1 zf-RVT PF13966.6 GAN03890.1 - 1.5e-08 35.2 0.3 2.4e-08 34.6 0.1 1.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase LNS2 PF08235.13 GAN03891.1 - 1.1e-101 339.1 0.0 1.8e-101 338.3 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 GAN03891.1 - 2.1e-42 143.2 0.1 3.9e-42 142.4 0.1 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 GAN03891.1 - 1.8e-19 69.7 4.8 2.4e-19 69.4 0.0 2.7 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF4820 PF16091.5 GAN03891.1 - 5.8 6.2 17.3 0.58 9.5 9.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Glyco_hydro_47 PF01532.20 GAN03892.1 - 1.3e-120 403.5 0.0 1.9e-120 402.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 GAN03892.1 - 1.1e-09 38.2 0.0 2.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 PA domain ADH_N PF08240.12 GAN03893.1 - 1e-30 105.8 1.8 2.1e-30 104.8 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN03893.1 - 6.8e-12 45.5 0.1 1.1e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAN03893.1 - 3.7e-09 36.4 5.9 2.7e-07 30.3 5.9 3.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAN03893.1 - 4.1e-07 31.1 0.2 7.1e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 GAN03893.1 - 0.012 14.9 0.2 0.019 14.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 GAN03893.1 - 0.013 15.6 0.2 0.32 11.0 0.2 2.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 GAN03893.1 - 0.014 14.7 0.1 0.031 13.5 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAN03893.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 GAN03893.1 - 0.095 11.4 0.4 0.15 10.7 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein SET PF00856.28 GAN03894.1 - 3.3e-18 66.7 9.6 9.3e-18 65.2 0.0 4.2 4 1 0 4 4 4 1 SET domain AWS PF17907.1 GAN03894.1 - 3.9e-11 42.8 10.5 3.9e-11 42.8 10.5 2.3 2 0 0 2 2 2 1 AWS domain WW PF00397.26 GAN03894.1 - 9.7e-09 35.2 2.0 2.4e-08 33.9 2.0 1.7 1 0 0 1 1 1 1 WW domain SRI PF08236.11 GAN03894.1 - 9.1e-07 29.0 5.2 9.1e-07 29.0 5.2 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.11 GAN03894.1 - 0.00084 19.3 1.2 0.0027 17.7 0.2 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain CDC45 PF02724.14 GAN03894.1 - 1.8 6.8 20.9 0.12 10.7 6.8 2.4 2 0 0 2 2 2 0 CDC45-like protein Sigma70_ner PF04546.13 GAN03894.1 - 2.6 7.9 18.4 1 9.2 5.5 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 GAN03894.1 - 3.5 8.1 40.1 0.12 12.8 9.8 3.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GAN03894.1 - 4.1 6.6 27.6 0.93 8.8 11.4 2.5 2 0 0 2 2 2 0 NOA36 protein DUF2924 PF11149.8 GAN03894.1 - 9.2 6.7 6.8 1.7 9.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Gtr1_RagA PF04670.12 GAN03895.1 - 9.5e-82 273.8 0.6 1.3e-81 273.4 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAN03895.1 - 2.3e-07 30.4 0.2 6.3e-07 29.0 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 GAN03895.1 - 9.4e-06 25.8 0.4 3.7e-05 23.9 0.0 2.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN03895.1 - 5.2e-05 22.9 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAN03895.1 - 0.00085 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Barstar PF01337.18 GAN03895.1 - 0.0015 18.5 0.3 16 5.6 0.1 3.4 3 0 0 3 3 3 2 Barstar (barnase inhibitor) Fe-S_biosyn PF01521.20 GAN03896.1 - 3.3e-20 72.4 0.0 4.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis F-box PF00646.33 GAN03898.1 - 1.8e-06 27.6 0.4 4.4e-06 26.4 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN03898.1 - 2.3e-05 24.2 0.4 4.7e-05 23.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GAN03898.1 - 0.0026 17.6 0.4 0.0062 16.4 0.1 1.8 2 0 0 2 2 2 1 F-box WD40 PF00400.32 GAN03899.1 - 4.1e-50 166.7 18.1 8e-07 29.7 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN03899.1 - 2.9e-17 62.7 2.2 0.00034 20.9 0.0 6.2 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN03899.1 - 2.4e-07 30.9 1.2 3.8e-05 23.7 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAN03899.1 - 3.6e-05 22.6 9.5 0.027 13.1 0.1 4.3 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 GAN03899.1 - 5.6e-05 22.6 1.6 0.13 11.6 0.0 3.6 3 1 0 4 4 4 2 WD40-like domain LisH_TPL PF17814.1 GAN03899.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain BBS2_Mid PF14783.6 GAN03899.1 - 0.0047 16.9 0.9 0.52 10.4 0.1 4.2 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 GAN03899.1 - 0.045 13.7 0.1 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat LisH PF08513.11 GAN03899.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 LisH QueH PF02677.14 GAN03899.1 - 0.76 9.9 4.1 1.7 8.7 0.3 2.9 2 1 1 3 3 3 0 Epoxyqueuosine reductase QueH MOZ_SAS PF01853.18 GAN03902.1 - 3.5e-84 280.9 0.2 5.7e-84 280.2 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAN03902.1 - 2.8e-22 78.1 4.5 7.3e-22 76.7 4.5 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAN03902.1 - 2.4e-20 72.1 0.1 6.3e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 GAN03902.1 - 0.0074 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN03902.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_Mga PF08280.11 GAN03902.1 - 0.052 13.6 0.5 0.12 12.4 0.5 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.12 GAN03902.1 - 0.073 13.0 0.4 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 HTH domain DUF2314 PF10077.9 GAN03902.1 - 0.1 12.7 1.4 0.22 11.6 1.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Phage_portal PF04860.12 GAN03902.1 - 0.1 11.7 0.0 0.26 10.4 0.0 1.6 1 1 0 1 1 1 0 Phage portal protein ASFV_J13L PF05568.11 GAN03902.1 - 3.8 7.2 7.8 8.9 6.0 7.8 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein ERCC3_RAD25_C PF16203.5 GAN03903.1 - 4.2e-125 415.9 0.5 7.5e-125 415.1 0.5 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 GAN03903.1 - 1.7e-39 134.9 0.0 5.4e-39 133.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN03903.1 - 3.9e-16 59.5 0.0 9.9e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN03903.1 - 7.2e-11 42.4 0.0 2.8e-10 40.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GAN03903.1 - 3.4e-09 35.9 0.0 4.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 GAN03903.1 - 9.3e-05 22.3 0.3 0.00037 20.3 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Polysacc_deac_1 PF01522.21 GAN03904.1 - 1.3e-26 92.9 0.1 2.4e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2408 PF10303.9 GAN03905.1 - 1.5e-43 148.6 0.3 1.7e-24 86.9 0.0 4.5 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) F-box-like PF12937.7 GAN03907.1 - 8.7e-06 25.5 0.4 2.5e-05 24.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03907.1 - 0.0069 16.2 0.1 0.022 14.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN03908.1 - 0.00083 19.2 1.0 0.014 15.3 1.0 2.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 GAN03908.1 - 0.058 13.3 0.2 10 6.1 0.1 3.2 2 0 0 2 2 2 0 F-box domain NOA36 PF06524.12 GAN03909.1 - 2.8 7.2 5.9 4.4 6.5 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein E7 PF00527.18 GAN03909.1 - 7.9 6.8 8.7 4.7 7.5 1.8 2.8 2 2 0 2 2 2 0 E7 protein, Early protein Enolase_N PF03952.16 GAN03911.1 - 0.0029 17.8 0.2 0.0034 17.6 0.2 1.0 1 0 0 1 1 1 1 Enolase, N-terminal domain DUF3990 PF13151.6 GAN03911.1 - 0.029 14.0 0.5 0.037 13.7 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) RNA_polI_A34 PF08208.11 GAN03913.1 - 1e-26 94.3 11.4 1.3e-26 93.9 11.4 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DTHCT PF08070.11 GAN03913.1 - 7.7 7.3 35.0 0.6 10.9 20.3 2.8 2 2 0 2 2 2 0 DTHCT (NUC029) region ubiquitin PF00240.23 GAN03914.1 - 2.6e-22 78.3 0.0 4.4e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAN03914.1 - 3.2e-11 42.9 0.2 5.5e-11 42.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 GAN03914.1 - 3.3e-08 33.3 0.5 6.8e-08 32.3 0.5 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TBK1_ULD PF18396.1 GAN03914.1 - 9.4e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GAN03914.1 - 0.00014 22.3 0.0 0.00029 21.3 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAN03914.1 - 0.0024 17.9 0.5 0.021 14.9 0.5 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAN03914.1 - 0.0029 17.7 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mucin PF01456.17 GAN03914.1 - 0.0049 16.9 6.3 0.013 15.5 6.3 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein RPN13_C PF16550.5 GAN03914.1 - 0.0056 16.8 0.2 0.013 15.6 0.2 1.7 1 0 0 1 1 1 1 UCH-binding domain HOIP-UBA PF16678.5 GAN03914.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair YukD PF08817.10 GAN03914.1 - 0.094 13.4 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_5 PF18037.1 GAN03914.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 GAN03914.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 CUE domain GerD PF17898.1 GAN03914.1 - 0.16 11.9 7.6 0.76 9.7 4.1 3.0 2 1 1 3 3 3 0 Spore germination GerD central core domain XPC-binding PF09280.11 GAN03914.1 - 0.17 11.6 8.9 0.58 9.9 7.4 2.7 1 1 1 2 2 2 0 XPC-binding domain STI1 PF17830.1 GAN03914.1 - 2 8.4 20.6 1 9.4 3.4 3.8 2 2 2 4 4 4 0 STI1 domain DUF2362 PF10154.9 GAN03915.1 - 4e-71 240.5 35.6 6.5e-34 117.7 0.1 4.4 2 1 2 4 4 4 3 Uncharacterized conserved protein (DUF2362) UBA PF00627.31 GAN03915.1 - 8.3e-06 25.6 0.2 1.8e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SUIM_assoc PF16619.5 GAN03915.1 - 0.12 12.4 0.0 0.12 12.4 0.0 4.8 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Polysacc_deac_1 PF01522.21 GAN03916.1 - 9.2e-37 125.7 0.0 2e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN03916.1 - 0.075 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 MGC-24 PF05283.11 GAN03916.1 - 0.18 12.2 7.3 0.36 11.3 7.3 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-met2 PF12907.7 GAN03917.1 - 7.9e-18 64.3 4.7 1.2e-17 63.8 4.7 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 GAN03917.1 - 1.2e-06 29.2 19.3 3.3e-06 27.9 13.9 2.1 2 0 0 2 2 2 2 4F5 protein family Erg28 PF03694.13 GAN03918.1 - 2.4e-39 134.1 3.6 2.6e-39 134.0 1.5 2.2 2 0 0 2 2 2 1 Erg28 like protein DUF3176 PF11374.8 GAN03918.1 - 1.4e-10 41.3 2.7 2e-10 40.8 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) DUF997 PF06196.12 GAN03918.1 - 2.3 8.3 7.7 0.22 11.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF997) TRAPPC9-Trs120 PF08626.11 GAN03919.1 - 0 1116.0 3.0 0 1115.8 3.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ndc1_Nup PF09531.10 GAN03919.1 - 0.015 14.1 0.7 0.024 13.4 0.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_12 PF13424.6 GAN03919.1 - 0.18 12.1 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Per1 PF04080.13 GAN03920.1 - 3.8e-91 305.4 7.9 4.6e-91 305.1 7.9 1.0 1 0 0 1 1 1 1 Per1-like family Ferritin PF00210.24 GAN03921.1 - 3.6e-39 133.9 2.0 4.2e-39 133.7 2.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 GAN03921.1 - 2.5e-08 34.4 0.1 3.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Rubrerythrin Amidohydro_1 PF01979.20 GAN03921.1 - 0.039 13.3 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family Nitr_red_assoc PF09655.10 GAN03921.1 - 0.047 14.3 0.5 0.072 13.7 0.5 1.3 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Ldh_1_C PF02866.18 GAN03921.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Aminotran_1_2 PF00155.21 GAN03922.1 - 5.2e-38 131.1 0.0 6.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S25 PF03297.15 GAN03924.1 - 7.7e-35 119.1 0.2 1e-34 118.8 0.2 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 GAN03924.1 - 0.015 14.8 0.4 0.03 13.9 0.4 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 GAN03924.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 MarR family LRR_4 PF12799.7 GAN03925.1 - 7e-13 48.6 14.3 0.00022 21.5 3.1 5.6 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAN03925.1 - 7.2e-12 44.9 15.0 2e-08 33.9 5.5 4.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 GAN03925.1 - 4.7e-06 26.2 0.3 0.13 11.8 0.0 3.1 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 GAN03925.1 - 0.013 16.0 11.5 13 6.8 0.1 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat Acyltransferase PF01553.21 GAN03926.1 - 1.8e-10 40.6 0.0 6.5e-09 35.5 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase Corona_nucleoca PF00937.18 GAN03926.1 - 0.045 12.8 4.6 0.076 12.0 4.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GPDPase_memb PF10110.9 GAN03926.1 - 0.19 10.5 6.0 0.3 9.8 6.0 1.2 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF498 PF04430.14 GAN03927.1 - 2.3e-29 101.6 0.0 3.9e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) IIGP PF05049.13 GAN03928.1 - 1.7e-23 83.3 0.0 3.7e-23 82.2 0.0 1.5 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 GAN03928.1 - 2.6e-07 30.7 0.0 6.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 GAN03928.1 - 0.0011 19.1 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 GAN03928.1 - 0.0036 16.8 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAN03928.1 - 0.0075 16.3 0.1 0.047 13.7 0.1 2.2 2 0 0 2 2 2 1 Dynamin family ABC_tran PF00005.27 GAN03928.1 - 0.012 16.1 0.1 0.029 14.9 0.1 1.9 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 GAN03928.1 - 0.019 14.9 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAN03928.1 - 0.025 14.9 0.3 0.076 13.4 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GAN03928.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 GAN03928.1 - 0.081 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 GAN03928.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 GAN03930.1 - 3.8e-19 69.1 0.0 7.9e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GAN03930.1 - 4.1e-16 59.1 6.6 1.5e-06 28.8 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 GAN03930.1 - 9.1e-12 44.2 3.0 0.026 14.8 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 GAN03930.1 - 3.7e-08 33.7 0.0 0.0035 17.7 0.1 4.2 3 1 1 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 GAN03930.1 - 6.9e-07 28.8 0.0 1.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 GAN03930.1 - 0.0011 19.2 0.1 4.6 7.6 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 GAN03930.1 - 0.0029 17.7 4.5 5.1 7.1 0.2 3.9 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAN03930.1 - 0.0056 17.2 0.3 0.028 14.9 0.3 2.3 1 0 0 1 1 1 1 HEAT-like repeat RTP1_C1 PF10363.9 GAN03930.1 - 0.055 13.6 1.7 6.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Ge1_WD40 PF16529.5 GAN03930.1 - 0.087 11.8 0.1 13 4.6 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CorA PF01544.18 GAN03931.1 - 3.1e-45 154.7 3.6 1.7e-22 80.1 0.2 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Seipin PF06775.14 GAN03931.1 - 0.037 14.1 0.3 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Putative adipose-regulatory protein (Seipin) U3_assoc_6 PF08640.11 GAN03932.1 - 3.5e-29 100.7 3.4 3.5e-29 100.7 3.4 3.7 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 GAN03932.1 - 4.7e-05 23.9 10.4 1.9 9.5 1.7 6.5 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN03932.1 - 0.057 13.8 3.7 12 6.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAN03932.1 - 0.81 9.7 14.7 7.1 6.6 0.8 5.4 3 2 0 4 4 4 0 Mad3/BUB1 homology region 1 CX9C PF16860.5 GAN03934.1 - 2.7e-22 78.5 17.2 6.7e-14 51.6 7.6 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 GAN03934.1 - 0.0043 17.2 3.4 0.0043 17.2 3.4 2.7 2 2 0 2 2 2 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 GAN03934.1 - 0.0094 15.9 3.6 0.0094 15.9 3.6 2.7 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 GAN03934.1 - 0.011 15.4 14.0 0.033 13.9 4.3 3.0 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 GAN03934.1 - 0.013 15.8 14.5 0.62 10.4 9.8 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 RsbU_N PF08673.10 GAN03934.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain COX17 PF05051.13 GAN03934.1 - 0.14 12.5 12.1 3.4 8.1 3.3 3.4 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 GAN03934.1 - 0.26 11.5 0.3 0.26 11.5 0.3 3.3 3 0 0 3 3 3 0 CHCH domain UPF0203 PF05254.12 GAN03934.1 - 6.9 7.0 16.6 3.5 8.0 0.3 3.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) Mid2 PF04478.12 GAN03935.1 - 0.0049 16.7 0.1 0.0049 16.7 0.1 3.7 3 2 2 5 5 5 1 Mid2 like cell wall stress sensor SDA1 PF05285.12 GAN03935.1 - 3.7 6.9 19.3 5.4 6.3 19.3 1.2 1 0 0 1 1 1 0 SDA1 Pox_A30L_A26L PF06086.12 GAN03936.1 - 0.0057 16.4 0.1 0.0057 16.4 0.1 1.1 1 0 0 1 1 1 1 Orthopoxvirus A26L/A30L protein DUF1218 PF06749.12 GAN03936.1 - 0.037 14.6 1.1 0.071 13.6 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Cytochrom_B558a PF05038.13 GAN03936.1 - 0.093 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit UPF0669 PF17065.5 GAN03937.1 - 0.35 10.6 3.6 0.47 10.2 3.6 1.1 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 Fis1_TPR_C PF14853.6 GAN03938.1 - 1.1e-23 83.1 0.1 1.8e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAN03938.1 - 8.2e-13 47.8 0.0 2.5e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat COPI_C PF06957.11 GAN03938.1 - 0.031 13.1 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUSP PF06337.12 GAN03939.1 - 0.0043 17.6 5.5 0.0077 16.8 0.0 3.6 4 0 0 4 4 4 1 DUSP domain F-box_4 PF15966.5 GAN03939.1 - 0.03 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 F-box Mis12 PF05859.12 GAN03941.1 - 1.3e-13 51.1 2.5 2.6e-13 50.2 2.5 1.5 1 0 0 1 1 1 1 Mis12 protein TetR_C_15 PF17918.1 GAN03941.1 - 0.036 14.8 0.5 1.8 9.3 0.1 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF4085 PF13315.6 GAN03941.1 - 0.062 12.9 5.1 0.04 13.6 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) Interferon PF00143.19 GAN03941.1 - 0.083 13.1 7.0 1.2 9.3 3.4 3.0 2 1 0 2 2 2 0 Interferon alpha/beta domain DUF883 PF05957.13 GAN03941.1 - 0.13 12.8 2.3 3.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 GAN03941.1 - 0.29 11.3 6.8 0.47 10.6 4.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 GAN03941.1 - 0.41 10.8 5.5 1.8 8.7 1.4 3.2 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 YtxH PF12732.7 GAN03941.1 - 0.45 11.1 1.5 48 4.6 0.0 3.1 2 1 0 2 2 2 0 YtxH-like protein DUF1664 PF07889.12 GAN03941.1 - 0.98 9.5 7.0 2.9 7.9 3.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) AAA PF00004.29 GAN03942.1 - 7.2e-82 272.4 0.0 1.9e-39 135.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Med7 PF05983.11 GAN03942.1 - 6.2e-53 179.7 5.8 1.2e-52 178.8 5.8 1.4 1 0 0 1 1 1 1 MED7 protein AAA_lid_3 PF17862.1 GAN03942.1 - 2.4e-26 91.3 3.7 2.9e-12 46.2 0.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAN03942.1 - 1.5e-13 51.5 0.4 2.4e-05 24.8 0.1 4.0 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 GAN03942.1 - 3.3e-10 39.9 0.0 0.0012 18.7 0.0 3.4 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Kdo PF06293.14 GAN03942.1 - 6.1e-10 38.8 0.1 1.6e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_5 PF07728.14 GAN03942.1 - 1.1e-09 38.4 0.2 0.0001 22.4 0.1 3.6 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Pkinase PF00069.25 GAN03942.1 - 5.1e-09 35.9 0.1 9.7e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain AAA_2 PF07724.14 GAN03942.1 - 2.2e-08 34.4 0.0 0.00073 19.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) APH PF01636.23 GAN03942.1 - 7.9e-07 29.2 0.0 6.1e-06 26.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family TIP49 PF06068.13 GAN03942.1 - 9.4e-07 28.3 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_25 PF13481.6 GAN03942.1 - 1e-06 28.5 0.6 0.057 13.0 0.0 4.0 2 1 1 3 3 3 1 AAA domain Pkinase_Tyr PF07714.17 GAN03942.1 - 1.2e-06 28.1 0.1 2.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GAN03942.1 - 1.2e-06 28.3 0.0 3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family AAA_33 PF13671.6 GAN03942.1 - 1.6e-06 28.3 0.0 0.00093 19.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN03942.1 - 6.6e-06 26.5 0.0 0.1 13.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 GAN03942.1 - 7.3e-06 26.0 0.0 0.048 13.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain NTPase_1 PF03266.15 GAN03942.1 - 1.2e-05 25.3 0.1 0.062 13.2 0.0 3.4 3 0 0 3 3 3 2 NTPase AAA_22 PF13401.6 GAN03942.1 - 1.8e-05 25.0 3.9 0.96 9.7 0.0 4.2 3 2 0 4 4 3 1 AAA domain Rad17 PF03215.15 GAN03942.1 - 2.6e-05 24.3 0.1 0.0016 18.4 0.0 3.0 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_7 PF12775.7 GAN03942.1 - 4.3e-05 23.1 0.0 0.061 12.8 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_3 PF07726.11 GAN03942.1 - 6.6e-05 22.8 0.1 0.22 11.4 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAN03942.1 - 0.00014 21.8 0.4 0.25 11.2 0.0 3.7 3 1 0 4 4 4 1 NACHT domain ATPase_2 PF01637.18 GAN03942.1 - 0.00016 21.7 0.1 1 9.2 0.1 3.4 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAN03942.1 - 0.00019 22.0 0.0 0.18 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAN03942.1 - 0.00024 21.1 0.0 0.34 10.9 0.0 2.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AFG1_ATPase PF03969.16 GAN03942.1 - 0.00052 19.0 0.0 0.015 14.2 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase ABC_tran PF00005.27 GAN03942.1 - 0.00053 20.5 0.0 1 9.9 0.0 3.0 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 GAN03942.1 - 0.00082 19.1 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Choline_kinase PF01633.20 GAN03942.1 - 0.0014 18.3 0.1 0.007 16.0 0.1 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase IstB_IS21 PF01695.17 GAN03942.1 - 0.0017 18.2 0.1 0.087 12.6 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 GAN03942.1 - 0.0028 18.1 0.6 1.5 9.2 0.1 3.4 4 0 0 4 4 2 1 AAA domain Bac_DnaA PF00308.18 GAN03942.1 - 0.0042 17.0 0.0 0.14 12.0 0.0 3.0 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.6 GAN03942.1 - 0.0045 16.8 0.0 2.8 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain WaaY PF06176.11 GAN03942.1 - 0.0063 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Mg_chelatase PF01078.21 GAN03942.1 - 0.0073 15.7 0.3 3 7.2 0.0 2.8 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 GAN03942.1 - 0.0078 15.4 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain EcKinase PF02958.20 GAN03942.1 - 0.0087 15.4 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase AAA_28 PF13521.6 GAN03942.1 - 0.017 15.4 0.3 4 7.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 GAN03942.1 - 0.037 13.2 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 GAN03942.1 - 0.037 14.4 0.1 6 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAN03942.1 - 0.044 13.5 0.0 6.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 GAN03942.1 - 0.055 13.2 0.0 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 GAN03942.1 - 0.059 12.6 0.0 1.1 8.4 0.1 2.7 2 1 0 2 2 2 0 KAP family P-loop domain RsgA_GTPase PF03193.16 GAN03942.1 - 0.061 13.2 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase Vps4_C PF09336.10 GAN03942.1 - 0.11 12.5 0.1 19 5.4 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain dsrm PF00035.26 GAN03943.1 - 9e-09 35.9 0.0 0.0023 18.6 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ofd1_CTDD PF10637.9 GAN03943.1 - 0.021 14.2 0.3 0.042 13.2 0.3 1.5 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term RhoGAP PF00620.27 GAN03946.1 - 1.1e-17 64.3 1.6 3.8e-17 62.5 1.6 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 GAN03946.1 - 1.5e-07 31.6 0.2 6.1e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MFS_1 PF07690.16 GAN03947.1 - 4.5e-56 190.3 31.7 1.6e-54 185.2 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN03947.1 - 4.8e-18 65.3 2.2 4.8e-18 65.3 2.2 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAN03947.1 - 1.5e-08 33.6 3.3 1.5e-08 33.6 3.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAN03947.1 - 1.1e-05 24.0 4.9 1.1e-05 24.0 4.9 2.9 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_5 PF05631.14 GAN03947.1 - 0.00036 19.5 1.1 0.00036 19.5 1.1 2.3 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM LapA_dom PF06305.11 GAN03947.1 - 0.014 15.2 10.1 2.6 7.9 0.1 3.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain MFS_3 PF05977.13 GAN03947.1 - 0.031 12.7 3.7 0.065 11.6 3.7 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1_like PF12832.7 GAN03947.1 - 0.31 9.9 17.4 0.0074 15.2 5.8 3.0 2 1 0 2 2 2 0 MFS_1 like family DUF2140 PF09911.9 GAN03947.1 - 2.6 7.5 4.5 5.5 6.5 4.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) HLH PF00010.26 GAN03948.1 - 6e-14 51.7 1.2 2e-13 50.0 1.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Omp_AT PF11557.8 GAN03948.1 - 0.36 9.8 3.4 0.75 8.7 3.4 1.5 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain zf-C2H2 PF00096.26 GAN03949.1 - 8.2e-13 48.0 7.4 2.2e-06 27.8 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN03949.1 - 6.4e-08 32.7 14.3 4.6e-07 30.0 3.4 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN03949.1 - 1.2e-07 31.9 6.5 0.0048 17.6 0.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAN03949.1 - 0.0021 18.3 3.4 0.0035 17.5 3.4 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger IR1-M PF12185.8 GAN03949.1 - 0.033 14.1 0.6 0.085 12.8 0.6 1.7 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain zf-LYAR PF08790.11 GAN03949.1 - 3.3 7.7 7.2 11 6.0 0.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 GAN03949.1 - 8.7 6.2 14.5 2.4 8.0 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Dopey_N PF04118.14 GAN03950.1 - 1.4e-106 356.1 14.9 7.7e-106 353.7 0.1 4.9 6 0 0 6 6 6 3 Dopey, N-terminal LMBR1 PF04791.16 GAN03950.1 - 6e-15 55.1 24.1 6e-15 55.1 24.1 3.0 3 1 0 3 3 3 1 LMBR1-like membrane protein PIN_6 PF17146.4 GAN03951.1 - 2.5e-30 104.8 0.0 6.7e-30 103.4 0.0 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 GAN03951.1 - 5.9e-29 100.0 2.3 1.4e-28 98.9 2.3 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 GAN03951.1 - 0.084 12.9 1.0 0.21 11.7 1.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon RRN9 PF10680.9 GAN03951.1 - 0.36 11.1 0.1 0.36 11.1 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor zf-NADH-PPase PF09297.11 GAN03951.1 - 1.1 9.0 3.4 1.5 8.6 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Med3 PF11593.8 GAN03951.1 - 2.1 7.5 9.8 2.5 7.2 5.3 2.5 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal Pox_Ag35 PF03286.14 GAN03951.1 - 6.6 6.5 15.7 4.6 7.0 12.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Rad1 PF02144.16 GAN03952.1 - 8.4e-33 113.6 0.1 9.8e-33 113.4 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AlaDh_PNT_N PF05222.15 GAN03953.1 - 6.8e-31 107.4 0.0 1e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 GAN03953.1 - 0.0063 15.8 0.0 0.077 12.3 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_20 PF00728.22 GAN03954.1 - 1.1e-91 307.9 0.5 1.5e-91 307.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAN03954.1 - 2.2e-18 67.2 0.0 6.7e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like GHL6 PF14871.6 GAN03954.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 CENP-O PF09496.10 GAN03955.1 - 7.6e-08 32.6 6.6 7.6e-08 32.6 6.6 2.0 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component SRP54_N PF02881.19 GAN03955.1 - 0.037 14.3 0.3 0.22 11.8 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain DivIVA PF05103.13 GAN03955.1 - 0.23 11.5 7.8 1.4 9.0 0.8 2.5 2 0 0 2 2 2 0 DivIVA protein ADIP PF11559.8 GAN03955.1 - 0.46 10.6 8.0 1 9.4 0.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DEK_C PF08766.11 GAN03956.1 - 1.3e-06 28.2 0.0 5.3e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 DEK C terminal domain CompInhib_SCIN PF11546.8 GAN03956.1 - 2 8.5 6.3 0.28 11.3 0.2 2.6 3 1 1 4 4 4 0 Staphylococcal complement inhibitor SCIN VHS PF00790.19 GAN03957.1 - 7.2e-31 106.9 0.4 1.4e-30 106.0 0.4 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 GAN03957.1 - 3.2e-17 61.9 2.2 5.4e-17 61.1 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAN03957.1 - 8.9e-16 57.5 0.2 1.9e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN03957.1 - 3e-13 49.2 0.1 1.2e-12 47.3 0.3 1.9 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 GAN03957.1 - 8e-13 48.5 1.9 2.5e-12 46.9 1.9 1.9 1 0 0 1 1 1 1 GAT domain SUIM_assoc PF16619.5 GAN03957.1 - 0.0067 16.5 0.3 0.0067 16.5 0.3 5.9 5 1 2 7 7 7 1 Unstructured region C-term to UIM in Ataxin3 DUF5457 PF17540.2 GAN03957.1 - 0.11 12.6 0.2 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5457) DUF3361 PF11841.8 GAN03957.1 - 0.14 12.0 0.6 0.33 10.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Trypsin PF00089.26 GAN03958.1 - 4.5e-21 75.7 0.0 9.7e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 GAN03958.1 - 0.0048 17.8 0.0 0.01 16.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain GshA PF08886.11 GAN03958.1 - 0.081 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase AMP-binding PF00501.28 GAN03959.1 - 2.3e-51 174.7 0.0 2.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_47 PF01532.20 GAN03960.1 - 1.8e-139 465.6 0.0 2.2e-139 465.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_S9 PF00326.21 GAN03961.1 - 3e-55 187.0 0.0 4.7e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 GAN03961.1 - 2.2e-41 142.0 5.4 4.6e-41 141.0 1.7 2.0 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 GAN03961.1 - 3e-05 23.4 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN03961.1 - 0.00059 19.6 0.0 0.0032 17.1 0.0 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 GAN03961.1 - 0.0072 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 GAN03961.1 - 0.013 15.1 0.0 0.046 13.3 0.0 1.8 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 GAN03961.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SWIRM-assoc_1 PF16495.5 GAN03962.1 - 0.16 12.0 3.3 0.3 11.1 3.3 1.4 1 0 0 1 1 1 0 SWIRM-associated region 1 SKG6 PF08693.10 GAN03962.1 - 4.4 6.8 8.2 7.2 6.1 8.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TPR_1 PF00515.28 GAN03963.1 - 3.5e-12 45.6 7.3 0.00017 21.3 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN03963.1 - 9.8e-07 28.4 2.8 0.094 12.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN03963.1 - 0.0026 18.0 2.7 0.0043 17.3 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAN03963.1 - 0.0091 16.5 0.1 0.087 13.3 0.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN03963.1 - 0.013 15.8 0.6 0.11 12.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN03963.1 - 0.018 15.2 2.5 20 5.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAN03963.1 - 0.033 13.9 0.2 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 TPR repeat Fis1_TPR_C PF14853.6 GAN03963.1 - 0.2 11.8 1.7 5.3 7.2 0.1 2.9 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Scramblase PF03803.15 GAN03964.1 - 5.2e-53 179.6 0.1 6.6e-53 179.3 0.1 1.1 1 0 0 1 1 1 1 Scramblase Indigoidine_A PF04227.12 GAN03965.1 - 9.6e-127 422.3 5.7 1.2e-124 415.4 5.7 2.0 1 1 0 1 1 1 1 Indigoidine synthase A like protein TPP_enzyme_N PF02776.18 GAN03965.1 - 0.0017 18.0 0.3 0.007 16.0 0.0 2.0 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PX PF00787.24 GAN03966.1 - 2.3e-23 82.3 2.7 8.1e-23 80.6 2.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 GAN03966.1 - 4.7e-13 49.2 8.8 1.5e-09 37.8 0.7 2.4 2 0 0 2 2 2 2 Vps5 C terminal like AKNA PF12443.8 GAN03966.1 - 0.014 16.1 0.5 0.014 16.1 0.5 2.7 3 0 0 3 3 3 0 AT-hook-containing transcription factor Phage_TAC_8 PF10666.9 GAN03966.1 - 0.021 15.1 5.6 0.54 10.5 0.4 3.1 2 1 1 3 3 3 0 Phage tail assembly chaperone protein Gp14 ()A118 BLOC1_2 PF10046.9 GAN03966.1 - 9.7 6.6 11.3 1 9.7 0.2 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4625 PF15418.6 GAN03967.1 - 0.048 13.9 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) GRP PF07172.11 GAN03968.1 - 0.05 14.3 0.1 0.082 13.6 0.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family PI3K_1B_p101 PF10486.9 GAN03968.1 - 0.14 9.9 3.9 0.16 9.8 3.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Lactamase_B_4 PF13691.6 GAN03969.1 - 1.5e-17 63.0 0.0 3.9e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 GAN03969.1 - 2.3e-13 50.1 0.0 1.7e-10 40.7 0.0 2.8 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAN03969.1 - 5.1e-07 29.9 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Reticulon PF02453.17 GAN03971.1 - 7.7e-21 74.7 3.0 1.1e-20 74.2 3.0 1.2 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 GAN03971.1 - 0.00056 19.4 1.6 0.00085 18.8 1.6 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) Peptidase_M22 PF00814.25 GAN03973.1 - 4.1e-88 295.6 0.0 4.9e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 GAN03973.1 - 0.0024 17.6 0.0 0.032 13.9 0.0 2.1 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus Cpn10 PF00166.21 GAN03974.1 - 1.3e-31 108.5 0.1 1.4e-31 108.4 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Gti1_Pac2 PF09729.9 GAN03975.1 - 4.3e-61 206.2 0.9 7.8e-61 205.3 0.9 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family Brix PF04427.18 GAN03976.1 - 3.2e-46 157.9 0.1 5e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 Brix domain DUF4746 PF15928.5 GAN03976.1 - 3.8 6.8 18.3 5.5 6.3 18.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP_sp32 PF07222.12 GAN03976.1 - 7.1 6.0 19.0 13 5.2 19.0 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AP-5_subunit_s1 PF15001.6 GAN03976.1 - 7.2 6.6 10.7 13 5.7 10.7 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF2151 PF10221.9 GAN03976.1 - 7.5 5.0 13.3 11 4.5 13.3 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator CHORD PF04968.12 GAN03977.1 - 6.5e-54 180.5 22.3 1.4e-27 96.2 7.7 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 GAN03977.1 - 2.3e-14 54.1 2.1 4.3e-14 53.3 2.1 1.5 1 0 0 1 1 1 1 CS domain BTK PF00779.19 GAN03977.1 - 6 6.8 10.2 3.8 7.4 0.2 3.2 4 0 0 4 4 4 0 BTK motif Rap_GAP PF02145.15 GAN03978.1 - 2.4e-58 196.7 0.0 7.2e-58 195.2 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Crust_neurohorm PF01147.17 GAN03978.1 - 0.16 11.8 0.2 0.46 10.3 0.2 1.7 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family GFO_IDH_MocA_C PF02894.17 GAN03978.1 - 0.18 11.8 0.4 27 4.8 0.5 2.8 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain zf-C2H2_10 PF16588.5 GAN03979.1 - 0.065 13.0 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger DUF613 PF04764.12 GAN03981.1 - 0.049 13.8 0.1 0.086 13.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF613) Glyco_hydro_46 PF01374.18 GAN03982.1 - 1.2e-31 110.0 0.0 2.7e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Opy2 PF09463.10 GAN03982.1 - 0.0054 17.0 5.7 0.0054 17.0 5.7 6.3 6 2 0 6 6 6 2 Opy2 protein UQ_con PF00179.26 GAN03983.1 - 4.9e-40 136.4 0.0 7.8e-40 135.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 GAN03984.1 - 3.3e-50 170.9 0.0 8.9e-50 169.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN03984.1 - 3.9e-38 131.2 0.0 8.5e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN03984.1 - 0.00021 20.2 0.0 0.00021 20.2 0.0 3.4 2 1 0 2 2 2 1 Fungal protein kinase Plasmodium_Vir PF05795.11 GAN03984.1 - 1.4 8.3 10.9 0.062 12.7 4.8 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF3439 PF11921.8 GAN03984.1 - 2.3 8.2 10.9 5.3 7.0 10.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cyt-b5 PF00173.28 GAN03985.1 - 2.2e-10 40.5 1.0 3.3e-10 40.0 1.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2013 PF09431.10 GAN03986.1 - 1.2e-48 164.8 3.7 1.2e-48 164.8 3.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) FA_hydroxylase PF04116.13 GAN03987.1 - 8.1e-23 81.2 13.7 8.1e-23 81.2 13.7 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily UDPGT PF00201.18 GAN03988.1 - 3.4e-28 98.7 0.9 1.2e-27 96.9 0.9 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.6 GAN03988.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.16 GAN03988.1 - 0.00035 20.6 0.1 0.00064 19.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 GAN03988.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain p450 PF00067.22 GAN03989.1 - 1.3e-54 185.7 0.0 1.9e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF966 PF06136.13 GAN03991.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF966) RAI16-like PF10257.9 GAN03992.1 - 1.6e-73 247.7 1.3 2.9e-73 246.8 1.3 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Pil1 PF13805.6 GAN03993.1 - 8.7e-40 136.9 0.9 1.7e-39 135.9 0.9 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 CorA PF01544.18 GAN03993.1 - 0.052 12.9 0.9 0.09 12.1 0.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_23 PF13476.6 GAN03993.1 - 0.058 13.9 2.4 2.9 8.4 0.6 2.4 2 1 0 2 2 2 0 AAA domain Spc24 PF08286.11 GAN03993.1 - 0.069 13.4 0.3 0.069 13.4 0.3 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Rx_N PF18052.1 GAN03993.1 - 0.14 12.4 0.8 7.4 6.9 0.4 2.4 1 1 1 2 2 2 0 Rx N-terminal domain Baculo_PEP_C PF04513.12 GAN03993.1 - 0.15 12.1 2.3 0.35 10.9 2.2 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TSC22 PF01166.18 GAN03993.1 - 0.25 11.7 2.0 1.2 9.5 0.2 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family ABC_tran_Xtn PF12848.7 GAN03993.1 - 1.9 8.5 6.6 1.9 8.6 0.8 2.6 2 0 0 2 2 2 0 ABC transporter DUF2205 PF10224.9 GAN03993.1 - 9.3 6.3 9.7 0.13 12.3 1.4 2.2 2 0 0 2 2 2 0 Short coiled-coil protein SUR7 PF06687.12 GAN03994.1 - 0.044 13.4 13.3 0.086 12.5 1.7 2.0 1 1 1 2 2 2 0 SUR7/PalI family Amastin PF07344.11 GAN03994.1 - 0.079 12.8 9.2 0.1 12.4 9.2 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF4131 PF13567.6 GAN03994.1 - 6.8 6.3 8.1 50 3.5 8.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TFIID_30kDa PF03540.13 GAN03996.1 - 1.8e-26 91.8 0.1 2.7e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 GAN03996.1 - 0.047 13.7 0.0 0.24 11.4 0.0 2.0 1 1 0 1 1 1 0 Bromodomain associated bZIP_1 PF00170.21 GAN03997.1 - 5.2e-11 42.5 6.6 5.2e-11 42.5 6.6 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAN03997.1 - 9.2e-07 28.9 7.7 2.2e-06 27.7 7.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 GAN03997.1 - 7.8e-05 23.0 1.1 7.8e-05 23.0 1.1 3.0 2 1 1 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.17 GAN03997.1 - 0.0072 16.8 4.3 0.0072 16.8 4.3 2.8 2 1 1 3 3 3 1 bZIP Maf transcription factor Aft1_HRA PF11786.8 GAN03997.1 - 0.012 15.9 1.2 0.012 15.9 1.2 2.3 2 0 0 2 2 2 0 Aft1 HRA domain ASD2 PF08687.11 GAN03997.1 - 0.075 12.6 8.9 0.047 13.3 7.2 1.5 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 DTHCT PF08070.11 GAN03997.1 - 0.25 12.1 8.7 0.084 13.6 5.4 2.0 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF4711 PF15829.5 GAN03997.1 - 0.3 11.0 6.0 0.08 12.9 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4711) HeLo PF14479.6 GAN03997.1 - 1.2 8.9 5.7 1.3 8.8 5.1 1.4 1 1 0 1 1 1 0 Prion-inhibition and propagation Hydrolase_4 PF12146.8 GAN03998.1 - 5.4e-07 29.1 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN03998.1 - 1.3e-06 28.3 0.0 0.00023 20.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN03998.1 - 1.6e-05 25.6 0.0 2.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GAN03998.1 - 0.0048 17.0 0.0 0.0066 16.6 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 GAN03998.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 GAN03998.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein TFIIA PF03153.13 GAN03999.1 - 2.2 8.2 7.8 2.6 7.9 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4807 PF16065.5 GAN04000.1 - 3e-25 88.3 0.3 6.2e-25 87.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) MamL-1 PF09596.10 GAN04000.1 - 0.17 12.1 1.6 1.1 9.6 0.9 2.2 2 0 0 2 2 2 0 MamL-1 domain LAGLIDADG_WhiA PF14527.6 GAN04002.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain WD40 PF00400.32 GAN04003.1 - 1e-42 143.3 25.8 2.6e-07 31.2 0.3 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 GAN04003.1 - 1.6e-12 46.9 12.7 0.0018 17.0 0.1 5.8 3 1 3 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.7 GAN04003.1 - 1.7e-12 47.0 0.3 1.7e-12 47.0 0.3 1.9 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 GAN04003.1 - 2.1e-11 44.0 5.2 0.23 11.8 0.1 6.1 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAN04003.1 - 3.3e-08 33.2 0.2 8.6e-08 31.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 GAN04003.1 - 1.9e-05 23.8 6.5 0.38 9.6 0.1 4.5 2 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 GAN04003.1 - 9.7e-05 21.5 3.1 0.25 10.3 0.1 3.9 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAN04003.1 - 0.00031 20.2 0.8 0.85 8.9 0.1 3.1 2 1 0 3 3 3 1 WD40-like domain F-box_4 PF15966.5 GAN04003.1 - 0.0069 16.3 0.3 0.19 11.6 0.0 3.2 3 0 0 3 3 3 1 F-box HARP PF07443.13 GAN04003.1 - 0.16 11.7 0.0 3.3 7.4 0.0 3.2 4 0 0 4 4 4 0 HepA-related protein (HARP) WD40 PF00400.32 GAN04006.1 - 6.3e-17 61.6 8.8 1.9e-05 25.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04006.1 - 3.3e-07 30.5 0.0 0.097 13.0 0.0 4.8 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN04006.1 - 4.3e-05 23.0 0.0 0.00014 21.3 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 GAN04006.1 - 0.0038 17.1 0.0 0.06 13.2 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAN04006.1 - 0.004 15.9 0.0 0.01 14.5 0.0 1.4 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Hira PF07569.11 GAN04006.1 - 0.062 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split SUR7 PF06687.12 GAN04007.1 - 5e-16 59.0 8.1 5e-16 59.0 8.1 2.0 2 0 0 2 2 2 1 SUR7/PalI family MRAP PF15183.6 GAN04007.1 - 0.015 15.3 7.1 0.11 12.4 0.0 3.0 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family Rhabdo_glycop PF00974.18 GAN04007.1 - 0.063 11.7 0.6 0.31 9.4 0.1 2.0 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein Cadherin_C_2 PF16492.5 GAN04007.1 - 0.18 12.6 0.1 0.18 12.6 0.1 2.9 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal FixH PF05751.11 GAN04007.1 - 1.7 8.7 4.6 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 FixH GN3L_Grn1 PF08701.11 GAN04009.1 - 2.5e-17 62.8 16.0 4.8e-15 55.4 6.1 3.5 2 1 2 4 4 4 2 GNL3L/Grn1 putative GTPase DDE_Tnp_ISL3 PF01610.17 GAN04009.1 - 0.11 12.2 6.6 0.13 11.9 6.6 1.2 1 0 0 1 1 1 0 Transposase RskA PF10099.9 GAN04009.1 - 1.4 9.2 10.2 0.39 11.0 7.0 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF1682 PF07946.14 GAN04009.1 - 7.3 5.7 17.1 8.9 5.4 17.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) GTP_cyclohydro2 PF00925.20 GAN04010.1 - 4.2e-64 215.0 0.0 7.3e-64 214.3 0.0 1.3 1 1 0 1 1 1 1 GTP cyclohydrolase II DEAD PF00270.29 GAN04011.1 - 1.2e-44 152.1 0.1 1.2e-44 152.1 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN04011.1 - 1.1e-26 93.3 0.3 1.1e-26 93.3 0.3 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.21 GAN04011.1 - 0.0016 18.0 8.7 0.039 13.5 0.1 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 GAN04011.1 - 0.091 12.1 0.1 0.091 12.1 0.1 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit API5 PF05918.11 GAN04011.1 - 0.11 11.3 15.9 0.18 10.6 15.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) EPL1 PF10513.9 GAN04011.1 - 3.5 8.0 14.2 33 4.8 14.3 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like ALMT PF11744.8 GAN04011.1 - 5.1 5.8 6.8 8.9 5.0 6.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter GRP PF07172.11 GAN04011.1 - 7.9 7.2 16.2 16 6.3 16.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family TFIIA PF03153.13 GAN04011.1 - 8.3 6.3 38.9 13 5.7 38.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mrx7 PF10906.8 GAN04013.1 - 0.00077 19.7 0.1 0.0011 19.2 0.1 1.3 1 0 0 1 1 1 1 MIOREX complex component 7 DUF4364 PF14277.6 GAN04013.1 - 0.051 13.3 0.0 0.051 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF2370 PF10176.9 GAN04014.1 - 1.5e-70 237.4 6.3 1.9e-61 207.6 0.1 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF2370) Levi_coat PF01819.17 GAN04014.1 - 0.035 14.1 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Levivirus coat protein AA_permease_2 PF13520.6 GAN04015.1 - 2.3e-45 155.2 60.2 2.6e-43 148.5 60.2 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN04015.1 - 3.7e-06 25.8 55.4 0.0007 18.3 28.2 2.4 1 1 1 2 2 2 2 Amino acid permease MoaC PF01967.21 GAN04016.1 - 3.7e-52 176.0 2.1 6e-52 175.3 2.1 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 GAN04016.1 - 1e-38 132.2 0.0 1.8e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 GAN04016.1 - 1.4e-26 93.8 1.6 6.9e-26 91.6 0.2 2.8 3 1 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 GAN04016.1 - 0.00089 19.5 0.0 0.0029 17.9 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain ThiG PF05690.14 GAN04016.1 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Ribosomal_S25 PF03297.15 GAN04017.1 - 2.8e-40 136.6 2.3 3.2e-40 136.4 2.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 GAN04017.1 - 0.017 15.0 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 GAN04017.1 - 0.018 14.6 0.4 0.028 14.0 0.4 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AIPR PF10592.9 GAN04017.1 - 0.04 13.5 0.3 0.067 12.8 0.3 1.4 1 1 1 2 2 2 0 AIPR protein BioT2 PF15368.6 GAN04017.1 - 0.095 12.7 0.2 0.13 12.2 0.2 1.3 1 1 0 1 1 1 0 Spermatogenesis family BioT2 ABC_membrane PF00664.23 GAN04018.1 - 9.1e-51 173.1 28.8 5.1e-29 101.8 6.3 3.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN04018.1 - 1.2e-43 149.0 0.0 3.1e-27 95.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN04018.1 - 7.5e-08 32.1 0.0 0.022 14.2 1.8 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 GAN04018.1 - 0.00017 20.7 0.0 0.12 11.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 GAN04018.1 - 0.0006 19.5 0.7 0.16 11.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAN04018.1 - 0.0021 17.7 0.3 1.2 8.7 0.1 2.8 3 0 0 3 3 3 2 AAA domain ResIII PF04851.15 GAN04018.1 - 0.0053 16.8 0.0 0.96 9.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 GAN04018.1 - 0.0091 15.4 0.3 1.9 7.8 0.1 2.4 2 0 0 2 2 2 1 KaiC AAA_16 PF13191.6 GAN04018.1 - 0.011 16.1 1.1 2.7 8.3 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 GAN04018.1 - 0.021 15.1 0.1 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAN04018.1 - 0.035 13.0 0.4 4.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 GAN04018.1 - 0.038 13.2 0.0 1.3 8.2 0.0 3.1 4 0 0 4 4 4 0 NB-ARC domain AAA_24 PF13479.6 GAN04018.1 - 0.087 12.5 2.2 0.13 12.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GAN04018.1 - 0.12 12.2 0.2 5.2 6.8 0.5 2.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3619 PF12279.8 GAN04018.1 - 0.12 12.7 0.5 1.1 9.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) DUF2075 PF09848.9 GAN04018.1 - 0.24 10.6 0.8 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 GAN04018.1 - 0.47 10.5 7.1 0.17 11.9 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain DHHC PF01529.20 GAN04019.1 - 4.7e-20 72.1 16.9 4.1e-19 69.0 16.9 2.1 1 1 0 1 1 1 1 DHHC palmitoyltransferase Thymidylat_synt PF00303.19 GAN04020.1 - 7.5e-117 389.2 0.0 8.5e-117 389.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Csm1 PF12539.8 GAN04021.1 - 1.5e-18 67.2 0.0 3.6e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF5094 PF17015.5 GAN04021.1 - 0.0001 22.5 4.0 0.0001 22.5 4.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF5094) DUF1993 PF09351.10 GAN04021.1 - 0.033 14.3 3.4 0.084 13.0 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF4174 PF13778.6 GAN04021.1 - 0.13 12.7 4.6 0.17 12.4 2.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) CHD5 PF04420.14 GAN04021.1 - 0.36 10.7 2.9 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 CHD5-like protein Mit_KHE1 PF10173.9 GAN04021.1 - 0.43 10.6 5.4 1 9.4 5.4 1.6 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Fez1 PF06818.15 GAN04021.1 - 0.84 10.1 22.1 0.11 13.0 17.4 1.7 2 0 0 2 2 2 0 Fez1 DUF4140 PF13600.6 GAN04021.1 - 6.2 7.3 6.9 13 6.3 0.3 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3391 PF11871.8 GAN04021.1 - 6.2 7.4 9.4 3.8 8.1 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Spc24 PF08286.11 GAN04021.1 - 7.5 6.9 15.9 1.4 9.2 3.9 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Sdh5 PF03937.16 GAN04022.1 - 1.3e-28 98.7 0.5 1.9e-28 98.2 0.5 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Pkinase PF00069.25 GAN04023.1 - 8.2e-51 172.9 0.0 1e-50 172.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04023.1 - 7.8e-24 84.4 0.0 9.9e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04023.1 - 0.00012 21.5 0.4 0.37 10.0 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Arf PF00025.21 GAN04024.1 - 3.6e-76 254.5 0.1 4.1e-76 254.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAN04024.1 - 1.2e-15 57.8 0.1 1.5e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN04024.1 - 6.8e-14 51.8 0.0 7.7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAN04024.1 - 1.1e-11 44.5 2.2 2.5e-07 30.2 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAN04024.1 - 1.7e-11 43.9 0.0 2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAN04024.1 - 1.5e-10 40.9 0.0 1.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN04024.1 - 2.8e-05 24.2 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAN04024.1 - 0.0036 16.6 0.1 0.0055 16.0 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase P5CR_dimer PF14748.6 GAN04025.1 - 2.6e-35 120.8 1.1 4.4e-35 120.1 1.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAN04025.1 - 5.3e-15 55.8 0.0 1.4e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 GAN04025.1 - 0.0011 19.0 0.4 0.0066 16.4 0.1 2.3 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 GAN04025.1 - 0.029 14.5 0.0 0.084 13.0 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.15 GAN04025.1 - 0.034 13.1 0.0 0.076 11.9 0.0 1.6 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ldr_toxin PF13940.6 GAN04025.1 - 0.23 11.5 2.2 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Zn_clus PF00172.18 GAN04026.1 - 0.002 18.2 16.0 0.0035 17.4 16.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TP1 PF02079.16 GAN04026.1 - 0.36 10.8 9.4 0.15 12.0 2.2 2.3 2 0 0 2 2 2 0 Nuclear transition protein 1 Pkinase PF00069.25 GAN04027.1 - 1.1e-69 234.8 0.0 1.6e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04027.1 - 1.8e-44 152.0 0.0 2.9e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 GAN04027.1 - 1.8e-40 138.9 5.9 7.9e-39 133.5 5.9 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 GAN04027.1 - 0.0023 17.9 0.0 0.0069 16.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 GAN04027.1 - 0.017 15.3 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 GAN04027.1 - 0.043 12.6 0.2 0.33 9.7 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase MIT PF04212.18 GAN04027.1 - 0.085 12.9 0.5 11 6.1 0.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RRM_1 PF00076.22 GAN04028.1 - 1.3e-20 73.0 0.2 9.2e-20 70.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAN04028.1 - 1.4e-05 25.2 6.3 2.1e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain SUIM_assoc PF16619.5 GAN04028.1 - 0.0023 18.0 0.9 0.0023 18.0 0.9 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ALMT PF11744.8 GAN04028.1 - 0.071 11.9 1.5 0.14 10.9 1.5 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Mannosyl_trans3 PF11051.8 GAN04029.1 - 4.5e-39 134.5 0.0 4.5e-28 98.4 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Cmc1 PF08583.10 GAN04030.1 - 2.2e-16 59.6 3.7 2.6e-16 59.4 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Bombinin PF05298.11 GAN04030.1 - 0.052 13.2 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 Bombinin COX17 PF05051.13 GAN04030.1 - 0.3 11.5 4.3 5.8 7.4 0.1 2.4 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Not1 PF04054.15 GAN04032.1 - 5.3e-91 305.3 9.0 5.3e-91 305.3 9.0 2.0 1 1 1 2 2 2 1 CCR4-Not complex component, Not1 Peptidase_M26_N PF05342.14 GAN04032.1 - 0.0035 16.8 0.2 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 M26 IgA1-specific Metallo-endopeptidase N-terminal region MyTH4 PF00784.17 GAN04032.1 - 0.047 14.2 1.6 0.53 10.8 0.4 3.2 2 2 0 3 3 3 0 MyTH4 domain FANCI_S2 PF14676.6 GAN04032.1 - 0.058 13.7 6.9 1.2 9.4 0.1 4.1 3 1 1 4 4 4 0 FANCI solenoid 2 zf-C3HC4_3 PF13920.6 GAN04033.1 - 2.2e-06 27.4 7.1 2.2e-06 27.4 7.1 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 GAN04033.1 - 0.001 19.4 0.9 0.001 19.4 0.9 5.9 7 1 0 7 7 7 1 Zinc finger, C2H2 type zf-C3HC4_2 PF13923.6 GAN04033.1 - 0.003 17.3 9.3 0.003 17.3 9.3 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 GAN04033.1 - 0.066 14.1 1.0 0.066 14.1 1.0 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger baeRF_family12 PF18856.1 GAN04033.1 - 0.16 12.6 2.5 1.9 9.0 0.0 2.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF5538 PF17692.1 GAN04033.1 - 0.2 11.7 3.7 0.17 12.0 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5538) Host_attach PF10116.9 GAN04033.1 - 0.3 11.7 0.0 0.3 11.7 0.0 2.9 3 0 0 3 3 3 0 Protein required for attachment to host cells CBP_BcsO PF17037.5 GAN04033.1 - 0.34 11.1 13.2 1.3 9.2 5.0 3.1 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsO Sec23_trunk PF04811.15 GAN04034.1 - 5.6e-59 199.7 0.0 9.1e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAN04034.1 - 3.6e-19 69.3 0.0 7.2e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAN04034.1 - 1.5e-13 50.6 4.5 3.6e-13 49.3 4.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 GAN04034.1 - 1.5e-13 50.4 0.5 4.7e-13 48.8 0.5 1.9 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 GAN04034.1 - 5.5e-06 26.2 0.0 2.2e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Gelsolin repeat Eapp_C PF10238.9 GAN04035.1 - 8.9e-32 110.2 8.8 2e-21 76.7 1.5 2.1 1 1 1 2 2 2 2 E2F-associated phosphoprotein zinc_ribbon_10 PF10058.9 GAN04035.1 - 0.23 11.2 4.4 0.26 11.1 0.0 2.8 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_2 PF13831.6 GAN04035.1 - 0.75 9.4 5.5 7.9 6.1 0.6 2.5 2 0 0 2 2 2 0 PHD-finger ATP-synt_F PF01990.17 GAN04036.1 - 4.6e-33 113.4 0.4 5.3e-33 113.2 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 GAN04036.1 - 0.052 12.8 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Ras PF00071.22 GAN04037.1 - 7.4e-61 204.5 0.5 8.9e-61 204.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN04037.1 - 3.1e-35 121.0 0.1 4.4e-35 120.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN04037.1 - 9.6e-14 51.2 0.1 1.3e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN04037.1 - 2.5e-05 24.3 0.1 4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN04037.1 - 0.00019 21.1 0.1 0.00053 19.6 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN04037.1 - 0.00027 20.9 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 GAN04037.1 - 0.001 18.5 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.14 GAN04037.1 - 0.0058 15.9 0.0 0.0074 15.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 GAN04037.1 - 0.0077 16.5 0.1 0.041 14.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.10 GAN04037.1 - 0.018 14.5 0.1 0.05 13.0 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 GAN04037.1 - 0.034 14.7 0.4 0.054 14.0 0.4 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 GAN04037.1 - 0.078 12.7 0.1 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAN04037.1 - 0.11 12.9 0.1 0.16 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 GAN04037.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Septin Pkinase PF00069.25 GAN04038.1 - 1.2e-51 175.7 0.0 2.4e-51 174.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04038.1 - 1.4e-34 119.5 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04038.1 - 4.5e-05 22.9 0.0 7.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN04038.1 - 0.00019 20.3 0.2 0.00043 19.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase FAD_binding_3 PF01494.19 GAN04040.1 - 2.3e-64 217.8 0.1 3.2e-63 214.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAN04040.1 - 0.00048 20.6 0.0 0.29 11.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN04040.1 - 0.0013 18.4 0.1 0.0045 16.6 0.0 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAN04040.1 - 0.0021 16.8 0.0 0.0066 15.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAN04040.1 - 0.0027 17.0 0.1 0.28 10.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAN04040.1 - 0.0049 16.0 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 GAN04040.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAN04040.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GAN04040.1 - 0.033 13.4 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAN04040.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAN04040.1 - 0.081 12.0 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein F-box-like PF12937.7 GAN04042.1 - 1.7e-08 34.3 0.1 5.1e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN04042.1 - 7.9e-08 32.5 8.4 0.0043 17.4 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAN04042.1 - 1.6e-07 30.8 21.2 0.11 12.6 0.2 7.0 7 0 0 7 7 7 4 Leucine Rich repeat F-box PF00646.33 GAN04042.1 - 2.1e-05 24.2 0.6 0.00014 21.6 0.1 2.8 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 GAN04042.1 - 0.0011 18.6 3.8 4.2 7.2 0.2 4.8 4 0 0 4 4 4 1 Leucine rich repeat DUF480 PF04337.12 GAN04042.1 - 0.049 13.7 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF480 IMUP PF15761.5 GAN04042.1 - 0.53 11.0 3.0 1.2 9.9 3.0 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein KxDL PF10241.9 GAN04043.1 - 7.3e-19 67.8 2.8 9.2e-19 67.5 2.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein AATF-Che1 PF13339.6 GAN04043.1 - 0.00047 20.9 0.6 0.00047 20.9 0.6 1.0 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DUF1043 PF06295.12 GAN04043.1 - 0.0046 17.0 1.6 0.0051 16.8 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Carbpep_Y_N PF05388.11 GAN04043.1 - 0.0047 17.5 0.3 0.0048 17.4 0.3 1.1 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide BLOC1_2 PF10046.9 GAN04043.1 - 0.02 15.2 1.0 0.028 14.7 1.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PI_PP_I PF18363.1 GAN04043.1 - 0.035 14.3 0.3 0.051 13.8 0.2 1.3 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain 7TMR-HDED PF07697.11 GAN04043.1 - 0.042 14.0 0.6 0.38 10.9 0.6 1.9 1 1 0 1 1 1 0 7TM-HD extracellular Methyltr_RsmB-F PF01189.17 GAN04044.1 - 4.9e-30 104.7 0.0 8e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F SLX9 PF15341.6 GAN04044.1 - 0.00082 19.8 0.4 0.0024 18.3 0.4 1.9 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 FtsJ PF01728.19 GAN04044.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2492 PF10678.9 GAN04044.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) Glyco_hydro_15 PF00723.21 GAN04045.1 - 1.8e-127 425.8 0.0 3.5e-127 424.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 ILEI PF15711.5 GAN04045.1 - 1.2e-23 83.4 0.0 4.3e-23 81.6 0.0 2.0 1 0 0 1 1 1 1 Interleukin-like EMT inducer SHNi-TPR PF10516.9 GAN04045.1 - 0.049 13.1 0.1 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 SHNi-TPR Fungal_trans PF04082.18 GAN04046.1 - 7.2e-23 81.0 1.1 9.7e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN04046.1 - 7.7e-11 41.9 11.7 2.4e-10 40.4 11.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCMT PF01135.19 GAN04047.1 - 1.8e-12 47.5 0.0 2.1e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SieB PF14163.6 GAN04047.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B Kelch_4 PF13418.6 GAN04048.1 - 6.2e-13 48.5 16.8 0.00089 19.2 0.0 6.8 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN04048.1 - 1e-12 47.8 3.6 0.00036 20.4 0.1 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAN04048.1 - 2.3e-10 40.0 1.5 0.34 11.0 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAN04048.1 - 2.7e-10 40.1 11.0 0.052 13.9 0.1 6.2 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 GAN04048.1 - 8.3e-05 22.8 10.3 0.1 12.9 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN04048.1 - 0.0047 16.5 10.7 0.051 13.2 0.4 5.3 6 1 0 6 6 6 1 Kelch motif Podoplanin PF05808.11 GAN04048.1 - 1.2 9.2 6.8 0.11 12.6 0.8 2.0 2 0 0 2 2 2 0 Podoplanin Kelch_6 PF13964.6 GAN04049.1 - 1.4e-07 31.5 7.0 0.1 13.0 0.0 5.5 4 1 1 5 5 5 1 Kelch motif Kelch_5 PF13854.6 GAN04049.1 - 0.00024 21.0 0.8 2 8.5 0.0 4.4 4 0 0 4 4 4 1 Kelch motif DUF5305 PF17231.2 GAN04049.1 - 0.0065 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5305) EphA2_TM PF14575.6 GAN04049.1 - 0.016 16.1 0.0 0.032 15.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 GAN04049.1 - 0.017 15.0 1.1 0.06 13.3 0.0 2.2 1 1 1 2 2 2 0 TMEM154 protein family DUF4229 PF14012.6 GAN04049.1 - 0.028 14.5 0.2 0.047 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) FUN14 PF04930.15 GAN04049.1 - 0.038 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 FUN14 family Kelch_3 PF13415.6 GAN04049.1 - 0.044 14.1 5.7 0.71 10.2 0.1 4.6 5 0 0 5 5 5 0 Galactose oxidase, central domain Adeno_E3_CR2 PF02439.15 GAN04049.1 - 0.054 13.3 0.9 0.11 12.3 0.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kelch_2 PF07646.15 GAN04049.1 - 0.081 12.9 4.1 12 6.1 0.0 4.1 6 0 0 6 6 4 0 Kelch motif Amnionless PF14828.6 GAN04049.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless Kelch_1 PF01344.25 GAN04049.1 - 0.12 11.9 0.9 1 9.0 0.0 3.0 3 0 0 3 3 3 0 Kelch motif DUF4690 PF15756.5 GAN04049.1 - 0.16 12.6 0.8 0.42 11.2 0.2 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage PGF-CTERM PF18204.1 GAN04049.1 - 1.1 9.3 6.1 2.1 8.4 6.1 1.5 1 0 0 1 1 1 0 PGF-CTERM motif Gram_pos_anchor PF00746.21 GAN04049.1 - 2.4 8.2 5.6 0.19 11.7 0.3 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3425 PF11905.8 GAN04050.1 - 8.8e-11 41.9 1.5 3.5e-10 39.9 0.6 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 GAN04050.1 - 0.0028 17.7 13.8 0.22 11.7 0.6 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 GAN04050.1 - 0.048 13.8 16.2 0.41 10.8 15.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF2514 PF10721.9 GAN04050.1 - 0.24 11.4 2.4 0.48 10.4 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Jnk-SapK_ap_N PF09744.9 GAN04050.1 - 3.5 7.8 5.8 1.9 8.7 2.4 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Shisa PF13908.6 GAN04051.1 - 0.026 14.8 3.0 0.032 14.5 3.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 GAN04051.1 - 9.4 6.6 10.5 5.9 7.2 0.7 2.2 1 1 1 2 2 2 0 Orf78 (ac78) DUF3425 PF11905.8 GAN04052.1 - 4e-13 49.4 1.3 1.9e-12 47.2 1.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAN04052.1 - 8.3e-05 22.6 9.0 0.00028 20.9 9.0 1.9 1 0 0 1 1 1 1 bZIP transcription factor Helicase_Sgs1 PF11408.8 GAN04052.1 - 0.086 12.9 1.5 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Sgs1 RecQ helicase RasGAP_C PF03836.15 GAN04052.1 - 1.4 9.1 11.9 0.086 13.0 3.3 2.6 2 0 0 2 2 2 0 RasGAP C-terminus SHE3 PF17078.5 GAN04052.1 - 2.3 7.9 14.0 0.052 13.3 5.6 2.5 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 MaoC_dehydrat_N PF13452.6 GAN04053.1 - 0.00097 19.3 0.0 0.0091 16.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 GAN04053.1 - 0.0033 17.0 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain SNF5 PF04855.12 GAN04054.1 - 8e-54 182.9 5.3 4.7e-27 95.3 0.0 2.4 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 PBP1_TM PF14812.6 GAN04054.1 - 0.093 13.1 3.9 0.24 11.8 3.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GAN04054.1 - 1.3 8.3 3.7 0.96 8.7 2.1 1.5 2 0 0 2 2 2 0 NOA36 protein HEAT_2 PF13646.6 GAN04055.1 - 8.2e-13 48.6 0.2 1.4e-05 25.4 0.0 4.3 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAN04055.1 - 2e-11 43.1 1.3 0.13 12.5 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.7 GAN04055.1 - 1.2e-05 25.4 0.4 0.00027 21.2 0.1 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 GAN04055.1 - 2e-05 24.7 12.0 0.013 15.6 0.1 4.7 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 GAN04055.1 - 0.0013 18.0 1.3 0.033 13.4 0.0 2.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 GAN04055.1 - 0.0068 16.9 0.2 7.2 7.2 0.0 4.3 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAN04055.1 - 0.01 16.4 5.5 25 5.5 0.1 5.1 3 2 1 4 4 4 0 Vacuolar 14 Fab1-binding region DUF4042 PF13251.6 GAN04055.1 - 0.066 12.9 0.1 0.066 12.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) API5 PF05918.11 GAN04055.1 - 0.15 10.8 4.6 0.38 9.5 2.1 2.6 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) RICTOR_M PF14666.6 GAN04055.1 - 0.78 9.5 3.3 7.5 6.4 0.1 3.6 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain RAI1 PF08652.11 GAN04056.1 - 1.1e-07 31.9 0.9 2.5e-06 27.5 0.1 2.5 2 0 0 2 2 2 2 RAI1 like PD-(D/E)XK nuclease SRF-TF PF00319.18 GAN04057.1 - 2.6e-22 78.0 0.0 5.7e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) EIF4E-T PF10477.9 GAN04057.1 - 0.018 13.9 44.9 0.031 13.1 44.9 1.5 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RWD PF05773.22 GAN04058.1 - 1.7e-13 50.8 0.0 3.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain UPF0029 PF01205.19 GAN04058.1 - 3.6e-13 49.7 0.2 1.2e-12 48.0 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Peroxin-13_N PF04088.13 GAN04058.1 - 0.11 12.8 0.0 5.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Tcp11 PF05794.13 GAN04059.1 - 4.5e-48 164.4 1.2 4.5e-48 164.4 1.2 2.0 2 0 0 2 2 2 1 T-complex protein 11 DC_STAMP PF07782.13 GAN04060.1 - 0.12 12.2 4.3 6.8 6.5 0.2 2.9 2 1 0 2 2 2 0 DC-STAMP-like protein STAG PF08514.11 GAN04060.1 - 0.15 12.0 1.5 0.91 9.5 0.1 2.8 2 1 0 3 3 3 0 STAG domain SET PF00856.28 GAN04061.1 - 3.2e-11 43.9 0.4 1.7e-10 41.5 0.1 2.1 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 GAN04061.1 - 2.9e-06 27.3 13.1 2.9e-06 27.3 13.1 2.1 2 0 0 2 2 2 1 MYND finger Herpes_UL4 PF03277.13 GAN04061.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF4690 PF15756.5 GAN04062.1 - 0.02 15.5 0.2 0.072 13.7 0.2 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Phage_holin_3_6 PF07332.11 GAN04062.1 - 0.057 13.5 0.2 0.057 13.5 0.2 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MAP17 PF15807.5 GAN04062.1 - 0.058 13.6 0.7 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4381 PF14316.6 GAN04062.1 - 0.067 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5134 PF17197.4 GAN04062.1 - 0.08 12.8 1.5 0.17 11.8 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) TMEM154 PF15102.6 GAN04062.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family FixS PF03597.15 GAN04062.1 - 1.2 8.9 3.9 2.2 8.1 3.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF3439 PF11921.8 GAN04063.1 - 0.078 12.9 4.6 0.28 11.2 4.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Orthopox_35kD PF02250.15 GAN04063.1 - 0.086 12.5 0.5 0.13 11.9 0.5 1.2 1 0 0 1 1 1 0 35kD major secreted virus protein SSP160 PF06933.11 GAN04063.1 - 0.71 8.0 13.6 1.1 7.4 13.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.6 GAN04063.1 - 2.9 7.8 6.9 5.8 6.8 6.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family F-box-like PF12937.7 GAN04064.1 - 0.00035 20.4 2.1 0.00068 19.5 2.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04064.1 - 0.003 17.4 1.0 0.0059 16.5 1.0 1.5 1 0 0 1 1 1 1 F-box domain SSP160 PF06933.11 GAN04064.1 - 0.052 11.7 8.8 0.083 11.1 8.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DSPc PF00782.20 GAN04065.1 - 1.3e-07 31.5 0.2 1.1e-06 28.5 0.0 2.4 1 1 2 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN04065.1 - 3.8e-07 29.9 0.2 3.2e-06 26.9 0.0 2.0 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAN04065.1 - 1.1e-06 28.8 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAN04065.1 - 4.8e-05 23.5 0.0 9.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 GAN04065.1 - 0.0054 16.3 0.1 0.015 14.9 0.1 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 GAN04065.1 - 0.0096 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Rhodanese PF00581.20 GAN04065.1 - 0.015 15.8 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain Ribosomal_L32e PF01655.18 GAN04066.1 - 7.3e-49 164.7 0.5 1.1e-48 164.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 RabGAP-TBC PF00566.18 GAN04067.1 - 2.5e-54 184.2 3.0 6.1e-54 182.9 3.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CTNNBL PF08216.11 GAN04067.1 - 1.2 9.3 4.6 0.42 10.8 0.4 2.5 3 1 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Nop52 PF05997.12 GAN04068.1 - 1.9e-74 250.1 0.3 2.4e-74 249.8 0.3 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 GAN04068.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II L31 PF09784.9 GAN04069.1 - 5e-41 139.3 0.0 5.6e-41 139.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 ETC_C1_NDUFA4 PF04800.12 GAN04073.1 - 8.7e-36 122.1 0.7 1.2e-35 121.6 0.7 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Lon_C PF05362.13 GAN04074.1 - 1.6e-70 236.8 0.1 3.1e-70 235.9 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 GAN04074.1 - 2.3e-23 83.1 0.0 4.6e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 GAN04074.1 - 5.5e-22 78.7 0.3 5.1e-21 75.5 0.0 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 GAN04074.1 - 1.4e-08 34.6 0.0 4.7e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 GAN04074.1 - 2.3e-06 26.8 0.0 4.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_5 PF07728.14 GAN04074.1 - 7.9e-06 25.9 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAN04074.1 - 8.5e-05 22.7 0.0 0.0003 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAN04074.1 - 9.5e-05 22.7 0.0 0.013 15.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GAN04074.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAN04074.1 - 0.00021 21.1 0.0 0.00066 19.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAN04074.1 - 0.0008 19.8 0.2 0.0029 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAN04074.1 - 0.0018 18.2 0.2 0.0082 16.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 GAN04074.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAN04074.1 - 0.0065 16.2 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein ClpB_D2-small PF10431.9 GAN04074.1 - 0.012 15.6 0.1 0.21 11.7 0.2 2.7 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.6 GAN04074.1 - 0.023 15.2 0.2 0.066 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 GAN04074.1 - 0.025 13.7 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 GAN04074.1 - 0.047 14.1 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 GAN04074.1 - 0.11 13.1 0.3 1.5 9.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.12 GAN04074.1 - 0.15 12.0 1.2 0.65 9.9 0.0 2.7 4 0 0 4 4 2 0 NACHT domain SKI PF01202.22 GAN04074.1 - 0.17 12.0 0.2 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase Ran-binding PF05508.11 GAN04075.1 - 4.4e-48 163.9 5.4 3e-46 157.9 5.4 2.9 1 1 0 1 1 1 1 RanGTP-binding protein DUF3384 PF11864.8 GAN04075.1 - 0.0061 15.5 3.4 0.72 8.7 0.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) Alpha-amylase_C PF02806.18 GAN04077.1 - 5.3e-28 97.3 0.1 1.3e-27 96.1 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 GAN04077.1 - 3.2e-17 62.7 0.1 9.6e-17 61.1 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GAN04077.1 - 2e-12 47.3 0.1 2.2e-08 34.1 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Flp_N PF03930.14 GAN04077.1 - 0.15 12.0 0.2 0.45 10.5 0.2 1.7 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus F-box-like PF12937.7 GAN04078.1 - 2.5e-07 30.5 0.0 6.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04078.1 - 0.00073 19.4 0.0 0.0037 17.1 0.0 2.3 2 0 0 2 2 2 1 F-box domain ZapB PF06005.12 GAN04078.1 - 0.003 18.0 2.3 0.0062 17.0 1.1 2.2 2 0 0 2 2 2 1 Cell division protein ZapB Cnn_1N PF07989.11 GAN04078.1 - 0.034 14.3 0.6 0.14 12.3 0.6 2.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 GAN04078.1 - 0.034 14.8 4.2 0.074 13.7 1.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA LRR_4 PF12799.7 GAN04078.1 - 0.088 13.3 18.5 1.6 9.3 0.2 6.7 7 2 2 9 9 9 0 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 GAN04078.1 - 0.22 11.7 2.6 0.52 10.4 2.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 GAN04078.1 - 0.47 10.3 3.6 1.7 8.5 3.6 2.0 1 0 0 1 1 1 0 Septum formation initiator Phage_spike_2 PF18781.1 GAN04080.1 - 0.059 13.4 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Phage spike trimer DAGAT PF03982.13 GAN04081.1 - 1.3e-99 332.9 0.0 2.3e-99 332.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF3328 PF11807.8 GAN04081.1 - 4.1 7.1 5.5 13 5.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3328) Abhydrolase_3 PF07859.13 GAN04082.1 - 1.2e-23 84.1 0.0 1.9e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAN04082.1 - 8.1e-22 77.8 0.1 2.5e-21 76.1 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family FSH1 PF03959.13 GAN04082.1 - 4e-05 23.4 0.0 8.7e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF2974 PF11187.8 GAN04082.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ASH PF15780.5 GAN04083.1 - 2.1e-12 47.1 15.3 1.3 9.2 0.0 10.8 11 0 0 11 11 11 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 GAN04083.1 - 4.3e-09 36.4 0.4 0.22 11.7 0.0 6.3 6 0 0 6 6 6 3 Flagellar-associated PapD-like BsuPI PF12690.7 GAN04083.1 - 0.013 15.6 0.5 13 5.9 0.0 4.7 4 0 0 4 4 4 0 Intracellular proteinase inhibitor Transglut_C PF00927.22 GAN04083.1 - 0.029 14.5 0.0 4 7.6 0.0 4.3 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain TMEM131_like PF12371.8 GAN04083.1 - 0.33 11.3 9.8 27 5.1 0.0 7.0 7 1 1 8 8 8 0 Transmembrane protein 131-like Transferase PF02458.15 GAN04084.1 - 6.7e-25 87.6 0.0 3e-17 62.4 0.0 2.7 2 1 0 2 2 2 2 Transferase family Rrp15p PF07890.12 GAN04085.1 - 1.7e-33 115.8 7.5 1.7e-33 115.8 7.5 3.4 3 0 0 3 3 3 1 Rrp15p TPT PF03151.16 GAN04085.1 - 1.1e-27 97.2 23.8 1.6e-27 96.6 23.8 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN04085.1 - 3.8e-08 33.6 40.4 3.4e-07 30.5 14.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family GWT1 PF06423.12 GAN04085.1 - 0.0069 16.5 3.3 0.012 15.8 1.2 2.4 2 1 0 2 2 2 1 GWT1 OrsD PF12013.8 GAN04085.1 - 1.2 9.6 3.6 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D G-patch PF01585.23 GAN04086.1 - 4.5e-15 55.3 0.6 8e-15 54.5 0.6 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN04086.1 - 1.3e-06 28.4 0.5 1.3e-06 28.4 0.5 2.4 2 0 0 2 2 2 1 G-patch domain SOBP PF15279.6 GAN04086.1 - 3.4 8.2 12.2 4.3 7.9 12.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RED_N PF07808.13 GAN04086.1 - 4.1 6.9 18.4 0.042 13.4 3.2 2.7 1 1 2 3 3 3 0 RED-like protein N-terminal region HSP70 PF00012.20 GAN04087.1 - 6.8e-09 34.5 0.0 1.1e-07 30.5 0.0 2.1 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GAN04087.1 - 0.012 14.5 0.0 0.025 13.4 0.0 1.4 2 0 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.25 GAN04088.1 - 4.3e-62 209.9 0.0 1e-61 208.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04088.1 - 7.3e-38 130.3 0.0 1.5e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAN04088.1 - 3.7e-17 61.9 0.0 6.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 APH PF01636.23 GAN04088.1 - 1e-05 25.6 0.4 0.077 12.9 0.0 3.1 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 GAN04088.1 - 3.8e-05 23.1 0.0 7.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN04088.1 - 0.00011 21.2 0.0 0.00028 20.0 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN04088.1 - 0.00014 21.3 0.0 0.00039 19.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAN04088.1 - 0.013 15.2 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 GAN04088.1 - 0.099 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PCI PF01399.27 GAN04089.1 - 2.4e-11 44.1 0.1 1.4e-10 41.6 0.0 2.4 3 0 0 3 3 3 1 PCI domain PSCyt2 PF07583.11 GAN04089.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) CENP-T_C PF15511.6 GAN04090.1 - 3e-08 33.8 0.1 3.7e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 GAN04090.1 - 6.7e-05 23.0 0.1 9.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 GAN04090.1 - 0.00011 22.5 0.1 0.00014 22.1 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 GAN04090.1 - 0.00022 21.6 0.1 0.00025 21.4 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAN04090.1 - 0.0004 20.6 0.1 0.00076 19.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAN04090.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN04090.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 GAN04090.1 - 0.19 12.3 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 GAN04091.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAN04091.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAN04091.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 GAN04091.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 GAN04091.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAN04091.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN04091.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Fungal_trans PF04082.18 GAN04092.1 - 2e-15 56.5 11.0 2e-15 56.5 11.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN04092.1 - 1.6e-09 37.7 12.5 3.1e-09 36.8 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 GAN04093.1 - 4e-17 61.7 4.4 6.7e-17 61.0 4.4 1.3 1 0 0 1 1 1 1 PQ loop repeat PAP2_C PF14360.6 GAN04095.1 - 5.5e-16 58.9 9.9 5.5e-16 58.9 9.9 2.3 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 GAN04095.1 - 0.0046 16.7 7.6 0.0046 16.7 7.6 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 GAN04095.1 - 1 9.0 13.2 0.07 12.8 8.1 1.7 2 0 0 2 2 2 0 PAP2 superfamily MFS_1 PF07690.16 GAN04096.1 - 3.4e-35 121.6 25.2 4.3e-34 118.0 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN04096.1 - 2.4e-07 30.0 13.2 6e-07 28.7 13.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter KOG2701 PF09762.9 GAN04096.1 - 0.068 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Rhv PF00073.20 GAN04096.1 - 0.072 12.7 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 picornavirus capsid protein SH3_1 PF00018.28 GAN04097.1 - 3.1e-12 45.9 0.1 5.1e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN04097.1 - 4.6e-09 36.0 0.0 7.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN04097.1 - 1.4e-08 34.3 0.0 2.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 GAN04097.1 - 0.015 15.6 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Copper-fist PF00649.18 GAN04098.1 - 1.3e-17 63.0 3.9 4.1e-17 61.4 3.9 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain CN_hydrolase PF00795.22 GAN04099.1 - 1.3e-57 195.2 0.1 1.4e-57 195.0 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sulfotransfer_4 PF17784.1 GAN04100.1 - 1.8e-49 168.5 0.1 5.2e-49 167.0 0.1 1.8 1 0 0 1 1 1 1 Sulfotransferase domain BAG PF02179.16 GAN04100.1 - 1.9e-15 57.0 1.3 1.9e-15 57.0 1.3 2.1 2 0 0 2 2 2 1 BAG domain Myb_DNA-binding PF00249.31 GAN04100.1 - 6.2e-11 42.3 1.8 6.2e-11 42.3 1.8 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN04100.1 - 4.5e-09 36.4 0.3 1.9e-08 34.4 0.3 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cytochrom_B561 PF03188.16 GAN04100.1 - 4.5e-05 23.6 3.7 4.5e-05 23.6 3.7 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 ubiquitin PF00240.23 GAN04100.1 - 5.7e-05 22.8 0.1 0.00025 20.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAN04100.1 - 0.00015 22.1 0.5 0.00054 20.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-like domain SLIDE PF09111.10 GAN04100.1 - 0.041 13.9 9.6 0.092 12.8 0.0 4.5 5 1 0 5 5 5 0 SLIDE Ni_hydr_CYTB PF01292.20 GAN04100.1 - 0.047 13.3 0.7 0.12 12.0 0.7 1.6 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Sulfotransfer_3 PF13469.6 GAN04100.1 - 0.082 13.3 0.3 0.082 13.3 0.3 3.8 4 1 0 5 5 5 0 Sulfotransferase family Vip3A_N PF12495.8 GAN04100.1 - 0.46 10.4 2.4 1.1 9.2 2.4 1.6 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF3348 PF11828.8 GAN04101.1 - 0.025 14.3 0.9 0.044 13.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) DUF4176 PF13780.6 GAN04101.1 - 0.098 12.7 0.3 13 5.9 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4176) Chitin_synth_2 PF03142.15 GAN04102.1 - 1.3e-81 274.9 9.4 2.7e-62 211.1 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase DEK_C PF08766.11 GAN04102.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 GAN04102.1 - 0.00014 21.8 0.0 0.078 12.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAN04102.1 - 0.0043 16.9 0.0 0.14 12.0 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN04102.1 - 0.029 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Cyt-b5 PF00173.28 GAN04102.1 - 0.047 13.8 0.1 4.7 7.4 0.0 2.8 3 0 0 3 3 3 0 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 GAN04103.1 - 1.6e-44 151.7 0.8 5.4e-44 150.0 0.8 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN04103.1 - 3.4e-32 111.1 6.7 1.3e-31 109.2 0.1 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAN04103.1 - 0.011 16.0 0.1 0.035 14.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.12 GAN04103.1 - 1.4 9.1 15.4 0.22 11.8 2.0 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family Cyclin PF08613.11 GAN04104.1 - 5.6e-10 39.8 0.0 1.3e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN04104.1 - 0.0041 16.9 0.5 0.067 12.9 0.5 2.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain APP_Cu_bd PF12924.7 GAN04104.1 - 0.15 12.8 2.0 0.57 11.0 1.2 2.2 2 0 0 2 2 2 0 Copper-binding of amyloid precursor, CuBD LUC7 PF03194.15 GAN04105.1 - 1.7e-71 240.9 16.9 2.5e-71 240.3 16.9 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Ead_Ea22 PF13935.6 GAN04105.1 - 0.02 15.6 3.8 0.062 14.0 3.8 2.0 1 1 0 1 1 1 0 Ead/Ea22-like protein ArnB_C PF18677.1 GAN04105.1 - 0.024 14.8 3.2 0.84 9.8 0.5 2.6 1 1 1 2 2 2 0 Archaellum regulatory network B, C-terminal domain Ran-binding PF05508.11 GAN04105.1 - 0.36 9.8 4.1 0.42 9.6 0.7 2.2 2 0 0 2 2 2 0 RanGTP-binding protein CSN5_C PF18323.1 GAN04105.1 - 0.8 10.7 9.0 1.2 10.1 3.2 3.3 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain V_ATPase_I PF01496.19 GAN04105.1 - 1.7 6.5 8.2 2.1 6.1 8.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-met PF12874.7 GAN04105.1 - 2.5 8.6 4.2 2 9.0 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type EMP24_GP25L PF01105.24 GAN04105.1 - 2.8 7.8 6.3 0.2 11.6 1.3 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Trnau1ap PF17654.1 GAN04105.1 - 6.3 7.7 16.9 22 6.0 0.8 2.7 2 1 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins SHD1 PF03983.12 GAN04106.1 - 5.4e-11 42.2 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 F-box-like PF12937.7 GAN04106.1 - 0.0086 15.9 0.3 0.0086 15.9 0.3 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GAN04106.1 - 0.079 12.9 0.3 0.28 11.1 0.3 2.0 1 0 0 1 1 1 0 F-box domain YscJ_FliF_C PF08345.11 GAN04106.1 - 0.1 12.9 1.7 0.19 12.1 1.7 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal F-box-like PF12937.7 GAN04107.1 - 2e-06 27.6 1.5 3.9e-06 26.6 1.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04107.1 - 0.00037 20.3 0.1 0.00097 19.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAN04107.1 - 0.0096 15.8 0.7 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 F-box Zn_clus PF00172.18 GAN04108.1 - 1.9e-10 40.7 24.6 9.9e-06 25.6 8.8 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Col_cuticle_N PF01484.17 GAN04109.1 - 0.16 12.0 0.8 0.38 10.9 0.2 1.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain HELP PF03451.14 GAN04110.1 - 0.25 11.2 0.4 0.53 10.2 0.1 1.7 2 0 0 2 2 2 0 HELP motif Acyl-CoA_dh_1 PF00441.24 GAN04111.1 - 9.5e-29 100.5 0.9 1.4e-28 100.0 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAN04111.1 - 4.6e-25 88.5 0.0 9.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAN04111.1 - 1.9e-20 72.9 0.0 3.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAN04111.1 - 2.3e-08 34.4 1.1 5.4e-08 33.2 1.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 GAN04112.1 - 2.8e-20 72.8 0.0 1.1e-19 70.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAN04112.1 - 7.2e-05 21.7 0.0 7.2e-05 21.7 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GAN04112.1 - 0.0011 18.3 0.1 0.059 12.7 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase KAR9 PF08580.10 GAN04112.1 - 9.5 4.6 17.3 15 4.0 17.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SH3_9 PF14604.6 GAN04113.1 - 1.1e-37 127.7 5.3 4.6e-15 55.2 0.4 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 GAN04113.1 - 1.6e-33 114.0 5.2 2.3e-12 46.3 0.2 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 GAN04113.1 - 4.8e-31 106.2 0.8 4.6e-09 35.8 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain Nup54_57_C PF18570.1 GAN04113.1 - 0.5 10.0 4.9 18 5.0 0.2 3.5 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain SRF-TF PF00319.18 GAN04114.1 - 3.2e-21 74.6 0.1 5e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TFIIA PF03153.13 GAN04114.1 - 7.2 6.5 42.3 9.9 6.0 42.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 GAN04115.1 - 3e-47 161.7 2.8 4.2e-31 108.8 0.4 3.9 1 1 2 3 3 3 2 Velvet factor SBP_bac_5 PF00496.22 GAN04115.1 - 0.011 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle PBP1_TM PF14812.6 GAN04115.1 - 0.71 10.3 3.7 1.6 9.2 3.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_1 PF00175.21 GAN04116.1 - 7e-28 97.4 0.0 1.2e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAN04116.1 - 3.5e-25 88.2 0.0 5e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAN04116.1 - 2.3e-05 24.6 0.0 0.0008 19.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAN04116.1 - 0.0036 17.5 0.0 0.0064 16.7 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Ank_2 PF12796.7 GAN04117.1 - 1.5e-62 208.2 9.3 1e-19 70.9 1.1 6.4 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN04117.1 - 5.3e-54 179.9 4.8 7.5e-12 45.5 0.1 6.7 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN04117.1 - 3.7e-52 168.2 3.2 5e-07 29.5 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 GAN04117.1 - 8.3e-51 168.3 14.0 4e-07 30.2 0.0 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 GAN04117.1 - 8e-45 150.3 14.5 4.4e-06 26.9 0.0 8.8 4 3 5 9 9 9 8 Ankyrin repeats (many copies) CCDC84 PF14968.6 GAN04117.1 - 0.0035 17.0 3.6 0.0035 17.0 3.6 1.9 2 0 0 2 2 2 1 Coiled coil protein 84 DpaA_N PF16924.5 GAN04117.1 - 0.13 12.4 0.1 6.7 6.8 0.0 3.3 4 0 0 4 4 4 0 Dipicolinate synthase subunit A N-terminal domain DUF2122 PF09895.9 GAN04117.1 - 1.7 9.0 5.1 1.7 9.1 0.2 3.4 4 1 0 4 4 4 0 RecB-family nuclease (DUF2122) SUIM_assoc PF16619.5 GAN04117.1 - 7.4 6.7 15.5 0.35 11.0 6.9 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PHD PF00628.29 GAN04118.1 - 3e-08 33.4 9.8 6.4e-08 32.4 9.8 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 GAN04118.1 - 2.6e-07 31.2 0.0 2.6e-07 31.2 0.0 3.7 2 2 0 2 2 2 1 SET domain PHD_2 PF13831.6 GAN04118.1 - 0.34 10.5 4.8 0.65 9.6 4.8 1.5 1 0 0 1 1 1 0 PHD-finger His_Phos_2 PF00328.22 GAN04119.1 - 9.3e-90 301.7 0.4 1.2e-89 301.4 0.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GAN04119.1 - 4e-38 129.4 0.0 9.1e-38 128.3 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAN04119.1 - 7.8e-08 32.1 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 GAN04119.1 - 0.081 13.0 0.2 0.6 10.1 0.0 2.3 3 0 0 3 3 3 0 ATP-grasp domain HrpJ PF07201.11 GAN04119.1 - 0.092 13.1 0.8 0.2 12.0 0.8 1.5 1 0 0 1 1 1 0 HrpJ-like domain DAOA PF15199.6 GAN04119.1 - 0.095 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 D-amino acid oxidase activator Ribosomal_S7 PF00177.21 GAN04120.1 - 1.7e-30 105.7 1.8 1.1e-29 103.0 1.8 1.9 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e Bax1-I PF01027.20 GAN04121.1 - 9.9e-27 94.1 22.5 1.3e-26 93.8 22.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 GAN04121.1 - 2.1 6.5 9.5 2.3 6.4 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) tRNA-synt_2b PF00587.25 GAN04122.1 - 3.5e-42 144.4 0.0 7.2e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAN04122.1 - 6e-17 61.6 0.0 1.5e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain zf-C2H2_4 PF13894.6 GAN04123.1 - 1e-06 29.0 3.9 0.023 15.5 1.0 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN04123.1 - 6.3e-05 23.2 9.9 0.0017 18.7 2.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN04123.1 - 0.0095 16.3 2.6 0.0095 16.3 2.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf_ZIC PF18366.1 GAN04123.1 - 0.037 14.1 1.2 0.74 10.0 0.1 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 GAN04123.1 - 0.044 13.6 4.4 0.097 12.4 0.6 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 GAN04123.1 - 0.052 13.5 0.2 0.052 13.5 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 GAN04123.1 - 0.084 12.9 0.1 0.084 12.9 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Cpn60_TCP1 PF00118.24 GAN04124.1 - 1.1e-155 519.1 6.7 1.2e-155 518.9 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 GAN04124.1 - 0.063 13.1 0.1 0.32 10.8 0.1 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein zf-RING_2 PF13639.6 GAN04125.1 - 1.4e-06 28.5 2.8 1.4e-06 28.5 2.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAN04125.1 - 0.00012 21.9 6.2 0.00015 21.6 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN04125.1 - 0.00017 21.8 0.8 0.00017 21.8 0.8 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAN04125.1 - 0.00029 20.6 4.0 0.00029 20.6 4.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN04125.1 - 0.0004 20.3 3.5 0.0004 20.3 3.5 2.7 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN04125.1 - 0.0036 17.1 6.9 0.0037 17.1 2.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAN04125.1 - 0.025 14.3 1.2 0.068 12.9 0.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 GAN04125.1 - 0.052 13.6 3.5 0.29 11.2 0.4 2.7 2 0 0 2 2 2 0 RING-type zinc-finger DUF745 PF05335.13 GAN04125.1 - 0.053 13.2 0.1 0.053 13.2 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF745) DUF5022 PF16425.5 GAN04125.1 - 0.054 12.9 0.2 0.58 9.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5022) zf-ANAPC11 PF12861.7 GAN04125.1 - 0.12 12.5 1.4 0.18 11.9 0.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 GAN04125.1 - 0.17 11.8 1.8 0.39 10.6 1.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn-ribbon_8 PF09723.10 GAN04125.1 - 0.32 11.2 1.9 0.84 9.8 1.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4 PF00097.25 GAN04125.1 - 0.5 10.3 8.0 0.11 12.4 3.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AIP3 PF03915.13 GAN04126.1 - 2.9e-122 408.7 41.8 7e-122 407.4 41.8 1.6 1 1 0 1 1 1 1 Actin interacting protein 3 HSBP1 PF06825.12 GAN04126.1 - 0.077 12.9 1.6 4.3 7.3 0.3 3.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DHHW PF14286.6 GAN04126.1 - 0.35 10.1 5.1 0.66 9.2 5.1 1.4 1 0 0 1 1 1 0 DHHW protein BclA_C PF18573.1 GAN04127.1 - 0.067 13.1 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 BclA C-terminal domain UQ_con PF00179.26 GAN04128.1 - 1.2e-37 128.7 0.1 1.4e-37 128.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN04128.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 RWD domain HSP70 PF00012.20 GAN04129.1 - 0.008 14.4 0.0 0.057 11.6 0.0 2.1 3 0 0 3 3 3 1 Hsp70 protein NST1 PF13945.6 GAN04130.1 - 7.4e-45 153.4 13.0 7.4e-45 153.4 13.0 4.3 1 1 4 5 5 5 1 Salt tolerance down-regulator NOA36 PF06524.12 GAN04130.1 - 0.0092 15.3 15.4 0.0092 15.3 15.4 4.4 3 1 1 4 4 4 2 NOA36 protein Pribosyl_synth PF14572.6 GAN04130.1 - 0.076 13.0 0.5 0.19 11.8 0.5 1.6 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain CUE PF02845.16 GAN04131.1 - 4.8e-10 38.9 0.1 9.5e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 CUE domain PHA_gran_rgn PF09650.10 GAN04131.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) EF_assoc_2 PF08356.12 GAN04132.1 - 7.8e-36 121.9 0.0 2e-35 120.7 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 GAN04132.1 - 6e-30 104.0 0.0 1.8e-20 73.1 0.0 2.3 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 GAN04132.1 - 8e-30 102.3 2.6 1.5e-29 101.4 2.6 1.5 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 GAN04132.1 - 1.8e-18 66.9 0.0 3.4e-11 43.4 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAN04132.1 - 4.4e-09 36.4 0.1 0.0018 18.3 0.0 3.4 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 GAN04132.1 - 6.8e-08 32.9 0.0 0.0042 17.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain EF-hand_7 PF13499.6 GAN04132.1 - 3.3e-07 30.7 0.3 0.0058 17.0 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAN04132.1 - 2.1e-06 26.9 6.0 0.0071 15.8 0.7 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAN04132.1 - 2.1e-06 27.2 2.4 0.031 14.2 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain AAA PF00004.29 GAN04132.1 - 3.1e-06 27.7 0.0 0.047 14.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAN04132.1 - 4.4e-06 27.0 0.0 0.024 14.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 GAN04132.1 - 5.4e-06 26.9 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Arf PF00025.21 GAN04132.1 - 7.5e-06 25.5 0.0 0.0027 17.2 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 GAN04132.1 - 8.9e-06 26.3 0.0 0.052 14.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 GAN04132.1 - 1.3e-05 24.8 0.0 0.019 14.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 GAN04132.1 - 2e-05 24.6 0.1 0.28 11.1 0.0 2.9 2 1 1 3 3 2 2 NACHT domain Dynamin_N PF00350.23 GAN04132.1 - 3e-05 24.2 0.1 0.29 11.2 0.0 2.8 2 1 1 3 3 2 2 Dynamin family AAA_29 PF13555.6 GAN04132.1 - 3.1e-05 23.6 0.0 0.046 13.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAN04132.1 - 4.8e-05 23.3 0.2 0.085 12.8 0.0 3.9 4 0 0 4 4 4 1 RsgA GTPase AAA_24 PF13479.6 GAN04132.1 - 6.1e-05 22.8 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 GAN04132.1 - 7e-05 22.2 0.0 0.0086 15.4 0.0 2.4 2 0 0 2 2 2 1 Septin AAA_18 PF13238.6 GAN04132.1 - 0.00011 22.8 0.0 0.22 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAN04132.1 - 0.00019 21.4 0.0 0.031 14.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAN04132.1 - 0.00041 20.7 0.0 1 9.8 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 GAN04132.1 - 0.00049 20.3 0.0 0.89 9.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 GAN04132.1 - 0.00061 19.3 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 GAN04132.1 - 0.0008 19.2 0.0 0.077 12.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 GAN04132.1 - 0.00087 18.9 0.9 0.44 10.1 0.0 3.6 3 1 1 4 4 4 1 AAA domain G-alpha PF00503.20 GAN04132.1 - 0.001 18.3 0.1 0.75 8.9 0.0 2.6 3 0 0 3 3 2 1 G-protein alpha subunit ATPase_2 PF01637.18 GAN04132.1 - 0.0018 18.3 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MCM PF00493.23 GAN04132.1 - 0.0019 17.4 0.1 0.1 11.7 0.0 2.7 3 0 0 3 3 2 1 MCM P-loop domain Ploopntkinase3 PF18751.1 GAN04132.1 - 0.0019 18.1 0.0 0.86 9.5 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 cobW PF02492.19 GAN04132.1 - 0.0027 17.3 0.0 0.87 9.1 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAN04132.1 - 0.0031 16.7 0.0 0.95 8.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 GAN04132.1 - 0.0034 16.6 0.0 0.52 9.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) EF-hand_10 PF14788.6 GAN04132.1 - 0.0039 17.0 3.2 0.17 11.8 0.3 2.5 2 0 0 2 2 2 1 EF hand ATP_bind_1 PF03029.17 GAN04132.1 - 0.0056 16.5 0.1 5.1 6.8 0.0 3.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AFG1_ATPase PF03969.16 GAN04132.1 - 0.0076 15.2 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 AFG1-like ATPase Sigma54_activat PF00158.26 GAN04132.1 - 0.0088 15.8 0.0 6.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain EF-hand_5 PF13202.6 GAN04132.1 - 0.0099 15.3 7.2 0.054 13.0 0.6 2.6 2 0 0 2 2 2 1 EF hand AAA_17 PF13207.6 GAN04132.1 - 0.01 16.3 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAN04132.1 - 0.017 14.4 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 GAN04132.1 - 0.02 14.3 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 GAN04132.1 - 0.022 14.7 0.0 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 GAN04132.1 - 0.025 14.0 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_14 PF13173.6 GAN04132.1 - 0.031 14.3 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAN04132.1 - 0.033 13.4 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 GAN04132.1 - 0.052 12.9 0.2 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 GAN04132.1 - 0.055 13.8 0.0 1.6 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAN04132.1 - 0.063 13.0 0.0 11 5.7 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_8 PF13833.6 GAN04132.1 - 0.078 12.8 2.1 5.9 6.8 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair VirE PF05272.11 GAN04132.1 - 0.086 12.6 0.1 14 5.4 0.0 3.1 3 1 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.9 GAN04132.1 - 0.089 11.9 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Mg_chelatase PF01078.21 GAN04132.1 - 0.095 12.1 0.1 22 4.4 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.27 GAN04132.1 - 0.099 12.2 0.1 30 4.1 0.0 3.1 4 0 0 4 4 3 0 Elongation factor Tu GTP binding domain MobB PF03205.14 GAN04132.1 - 0.13 12.2 0.2 18 5.2 0.0 2.7 2 1 1 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.16 GAN04132.1 - 0.13 11.5 0.0 0.66 9.3 0.0 2.0 2 0 0 2 2 2 0 AIG1 family bMG5 PF17972.1 GAN04132.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain NTPase_1 PF03266.15 GAN04132.1 - 0.16 11.9 0.1 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 GAN04132.1 - 0.18 12.3 0.2 30 5.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAN04132.1 - 0.19 11.5 0.0 24 4.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 GAN04132.1 - 0.19 11.4 0.0 7.9 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DNA_ligase_A_M PF01068.21 GAN04133.1 - 1.9e-66 223.6 0.2 3.5e-66 222.7 0.2 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAN04133.1 - 1.7e-45 155.4 0.9 3.2e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAN04133.1 - 2.3e-25 89.1 0.0 1.4e-24 86.6 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Ndc1_Nup PF09531.10 GAN04133.1 - 0.056 12.1 1.3 0.082 11.6 1.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_ligase_OB_2 PF14743.6 GAN04133.1 - 0.078 13.0 0.3 15 5.7 0.0 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain Presenilin PF01080.17 GAN04133.1 - 0.62 8.8 2.0 0.96 8.1 2.0 1.2 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 GAN04134.1 - 4.2e-13 49.5 5.1 0.0067 17.2 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04134.1 - 1.2e-06 28.8 0.0 1.4 9.2 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 GAN04134.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) NUP214 PF16755.5 GAN04134.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PQQ_3 PF13570.6 GAN04134.1 - 0.075 13.6 0.2 24 5.6 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain UCR_hinge PF02320.16 GAN04135.1 - 1.8e-22 79.3 6.1 1.8e-22 79.3 6.1 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DUF2052 PF09747.9 GAN04135.1 - 0.079 13.1 5.3 0.094 12.8 5.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ORC_WH_C PF18137.1 GAN04135.1 - 0.2 11.7 2.0 0.22 11.6 2.0 1.4 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal MtrG PF04210.13 GAN04135.1 - 0.21 11.5 0.6 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G FYRN PF05964.14 GAN04137.1 - 2.2e-21 75.4 0.3 6.6e-21 73.9 0.3 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 GAN04137.1 - 5.8e-13 48.8 0.0 1.4e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus DUF2828 PF11443.8 GAN04138.1 - 9.9e-189 628.5 5.1 1.2e-188 628.2 5.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) zinc_ribbon_6 PF14599.6 GAN04139.1 - 6.8e-25 86.9 1.0 6.8e-25 86.9 1.0 5.1 4 2 0 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 GAN04139.1 - 2.8e-20 72.6 23.2 2.8e-20 72.6 23.2 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 GAN04139.1 - 3.5e-09 36.8 10.0 3.5e-09 36.8 10.0 5.9 3 2 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN04139.1 - 0.0012 18.6 12.2 0.0012 18.6 12.2 6.1 5 2 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN04139.1 - 0.0055 16.5 9.4 0.0055 16.5 9.4 5.8 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAN04139.1 - 0.011 15.7 10.8 0.011 15.7 10.8 4.7 4 1 0 4 4 4 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAN04139.1 - 0.012 15.6 13.3 0.012 15.6 13.3 6.9 2 1 2 4 4 4 0 zinc-RING finger domain ALAD PF00490.21 GAN04139.1 - 0.067 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Mucin PF01456.17 GAN04139.1 - 7.1 6.6 22.4 4.2 7.4 1.7 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Tcf25 PF04910.14 GAN04140.1 - 8.8e-94 314.4 2.1 8.8e-94 314.4 2.1 2.0 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Stm1_N PF09598.10 GAN04140.1 - 0.055 14.3 7.4 0.25 12.2 7.4 2.2 1 0 0 1 1 1 0 Stm1 SAM_KSR1 PF13543.6 GAN04140.1 - 0.067 13.3 3.6 4.4 7.5 0.1 2.9 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 DUF3153 PF11353.8 GAN04140.1 - 0.32 10.5 2.3 0.62 9.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Histone PF00125.24 GAN04140.1 - 1.7 9.0 9.6 3.6 8.0 9.6 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 O-antigen_lig PF13425.6 GAN04140.1 - 4.6 5.9 9.4 8.3 5.1 9.4 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GRASP55_65 PF04495.14 GAN04141.1 - 1.4e-63 213.3 0.0 3e-46 157.2 0.0 2.4 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 GAN04141.1 - 7.9e-07 28.8 0.0 0.0034 17.2 0.0 3.2 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 GAN04141.1 - 6.7e-05 23.1 0.0 0.011 16.0 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Pga1 PF10333.9 GAN04141.1 - 0.0065 16.4 4.4 0.018 14.9 4.4 1.8 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator PDZ PF00595.24 GAN04141.1 - 0.037 14.4 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DUF4330 PF14221.6 GAN04141.1 - 0.19 12.0 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Mg_trans_NIPA PF05653.14 GAN04142.1 - 6.4e-22 78.0 15.3 3.3e-12 46.1 7.3 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAN04142.1 - 0.00061 20.0 5.6 0.00061 20.0 5.6 2.7 3 0 0 3 3 3 2 EamA-like transporter family Ac76 PF05814.11 GAN04142.1 - 0.0015 18.5 2.4 0.0015 18.5 2.4 2.6 4 0 0 4 4 4 1 Orf76 (Ac76) DUF2304 PF10066.9 GAN04142.1 - 1.5 9.1 15.8 0.82 9.9 0.5 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) HTH_Tnp_Tc3_2 PF01498.18 GAN04143.1 - 1.3e-12 47.8 0.1 1.9e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Transposase Herpes_BLLF1 PF05109.13 GAN04145.1 - 0.69 7.8 14.4 0.91 7.4 14.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SPX PF03105.19 GAN04145.1 - 3.7 7.4 7.0 4.6 7.0 7.0 1.1 1 0 0 1 1 1 0 SPX domain Sel1 PF08238.12 GAN04146.1 - 5.5e-32 109.5 6.6 3.7e-07 30.6 0.1 8.1 8 0 0 8 8 8 6 Sel1 repeat TPR_12 PF13424.6 GAN04146.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat bZIP_1 PF00170.21 GAN04147.1 - 6.1e-10 39.1 19.5 8.3e-09 35.4 18.1 2.8 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAN04147.1 - 0.00025 21.1 17.7 0.045 13.8 4.4 2.4 2 0 0 2 2 2 2 Basic region leucine zipper FlaC_arch PF05377.11 GAN04147.1 - 0.0098 16.3 2.0 0.019 15.4 2.0 1.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) ZapB PF06005.12 GAN04147.1 - 0.01 16.3 10.1 0.01 16.3 10.1 2.0 2 1 0 2 2 2 0 Cell division protein ZapB CCDC85 PF10226.9 GAN04147.1 - 0.014 15.1 2.4 0.021 14.5 2.4 1.3 1 0 0 1 1 1 0 CCDC85 family CLZ PF16526.5 GAN04147.1 - 0.23 11.8 10.0 0.25 11.7 6.9 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 GAN04147.1 - 0.27 11.9 3.9 0.49 11.0 3.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Cnn_1N PF07989.11 GAN04147.1 - 0.36 11.0 8.5 0.22 11.7 5.8 1.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 GAN04147.1 - 0.45 9.8 10.6 0.59 9.4 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 GAN04147.1 - 0.51 10.7 4.3 3 8.2 4.2 2.3 1 1 0 1 1 1 0 TSC-22/dip/bun family SR-25 PF10500.9 GAN04147.1 - 0.78 9.3 30.0 0.84 9.2 13.9 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein RNase_H2-Ydr279 PF09468.10 GAN04147.1 - 0.89 9.7 7.0 1.6 8.9 6.9 1.5 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain V_ATPase_I PF01496.19 GAN04147.1 - 1.6 6.5 9.4 1.8 6.4 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lzipper-MIP1 PF14389.6 GAN04147.1 - 2.8 8.3 11.4 0.049 13.9 3.1 2.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF3446 PF11928.8 GAN04147.1 - 3 8.2 19.2 0.14 12.4 4.3 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Jnk-SapK_ap_N PF09744.9 GAN04147.1 - 5.1 7.3 14.2 2.2 8.5 11.4 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Zn_clus PF00172.18 GAN04148.1 - 2.6e-06 27.4 7.5 5.2e-06 26.5 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exonuc_VII_L PF02601.15 GAN04148.1 - 3.8 7.0 13.7 0.63 9.5 9.4 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Methyltransf_33 PF10017.9 GAN04149.1 - 1.2e-89 300.5 2.1 1.7e-89 300.0 2.1 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 GAN04149.1 - 5.6e-27 94.9 2.0 3.6e-13 49.7 0.6 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 GAN04149.1 - 1.5e-06 28.8 3.8 1.8e-06 28.5 1.6 2.4 2 1 0 2 2 2 1 DinB superfamily Pkinase PF00069.25 GAN04150.1 - 6.5e-65 219.1 0.0 9.7e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04150.1 - 9.5e-31 107.0 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN04150.1 - 0.0027 16.7 0.2 0.0042 16.1 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 GAN04150.1 - 0.055 13.0 1.3 0.073 12.7 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 GAN04150.1 - 0.076 12.9 0.2 0.26 11.2 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN04150.1 - 0.12 11.7 0.2 0.25 10.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLDc_2 PF13091.6 GAN04151.1 - 3.6e-27 94.8 0.2 8.3e-27 93.7 0.2 1.7 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 GAN04151.1 - 0.0034 17.0 7.1 0.0074 15.9 0.0 3.2 3 0 0 3 3 3 1 FAM83 A-H PLDc PF00614.22 GAN04151.1 - 0.024 14.8 0.1 0.062 13.5 0.1 1.7 1 0 0 1 1 1 0 Phospholipase D Active site motif BUD22 PF09073.10 GAN04151.1 - 0.034 13.5 16.3 0.046 13.1 16.3 1.1 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 GAN04151.1 - 4.5 7.7 13.2 7.7 7.0 3.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_M24 PF00557.24 GAN04152.1 - 4.2e-55 186.7 0.0 5.5e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAN04152.1 - 2.6e-20 72.4 0.0 8.6e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain SE PF08491.10 GAN04153.1 - 2.8e-103 344.7 0.0 3.9e-103 344.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GAN04153.1 - 6.9e-16 58.4 0.0 8.8e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GAN04153.1 - 1.3e-06 27.7 0.4 8.7e-06 25.1 0.4 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 GAN04153.1 - 7.3e-06 25.8 0.1 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAN04153.1 - 0.00011 21.5 2.2 0.022 13.8 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAN04153.1 - 0.00029 20.1 0.1 0.00064 19.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAN04153.1 - 0.0012 19.0 0.5 0.0028 17.8 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAN04153.1 - 0.0021 18.6 1.1 0.04 14.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN04153.1 - 0.0033 16.8 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN04153.1 - 0.015 14.5 1.2 0.039 13.2 1.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAN04153.1 - 0.023 13.8 0.3 1.9 7.4 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 GAN04153.1 - 0.028 13.8 0.1 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase HI0933_like PF03486.14 GAN04153.1 - 0.032 13.0 0.1 0.051 12.3 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 GAN04153.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDI PF00996.18 GAN04153.1 - 0.081 11.4 0.0 0.16 10.4 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor ThiF PF00899.21 GAN04153.1 - 0.14 11.5 0.7 1.1 8.6 0.2 2.1 2 0 0 2 2 2 0 ThiF family SAPS PF04499.15 GAN04154.1 - 8e-119 397.6 6.3 8e-119 397.6 6.3 4.1 3 2 0 3 3 3 1 SIT4 phosphatase-associated protein Aa_trans PF01490.18 GAN04155.1 - 5.6e-57 193.3 30.3 6.8e-57 193.0 30.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HTH_29 PF13551.6 GAN04156.1 - 0.0036 17.3 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 GAN04156.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Kelch_2 PF07646.15 GAN04159.1 - 7.8e-05 22.5 0.6 0.14 12.2 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 GAN04159.1 - 0.00029 21.0 7.5 9.4 6.7 0.5 5.4 5 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GAN04159.1 - 0.00056 19.4 11.5 0.17 11.5 3.3 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAN04159.1 - 0.0021 18.0 10.0 0.37 10.8 0.0 5.1 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN04159.1 - 0.0086 16.1 2.6 0.61 10.1 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 GAN04159.1 - 1.9 8.8 11.8 4 7.8 0.2 4.5 5 1 0 5 5 5 0 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN04160.1 - 7.7e-08 32.4 6.9 0.01 16.1 0.3 5.6 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAN04160.1 - 7.9e-08 31.8 7.9 0.0096 15.5 0.4 4.5 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAN04160.1 - 6.4e-07 29.1 0.4 0.061 13.3 0.0 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAN04160.1 - 0.0001 22.2 6.1 0.2 11.7 0.1 4.8 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN04160.1 - 1.9 8.9 8.6 3.6 8.0 0.1 4.2 4 1 0 4 4 4 0 Galactose oxidase, central domain TMEM164 PF14808.6 GAN04163.1 - 1.6e-26 93.2 1.5 2.1e-26 92.8 1.5 1.0 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.10 GAN04163.1 - 8.2e-07 28.8 13.7 1e-06 28.5 13.7 1.2 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) Peptidase_M49 PF03571.15 GAN04165.1 - 5.7e-231 767.7 0.6 7e-231 767.4 0.6 1.1 1 0 0 1 1 1 1 Peptidase family M49 Kelch_4 PF13418.6 GAN04166.1 - 4.6e-11 42.6 3.8 1.2e-08 34.9 0.0 3.9 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN04166.1 - 2.3e-08 33.8 0.2 0.0061 16.5 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Gelsolin PF00626.22 GAN04166.1 - 0.024 14.5 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat Kelch_6 PF13964.6 GAN04166.1 - 0.053 13.8 0.2 6.7 7.2 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Syndecan PF01034.20 GAN04166.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Kelch_3 PF13415.6 GAN04166.1 - 0.2 12.0 4.4 0.22 11.8 0.1 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain SKG6 PF08693.10 GAN04166.1 - 1.7 8.1 5.4 0.18 11.2 0.4 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Kelch_5 PF13854.6 GAN04167.1 - 0.0011 18.8 2.6 0.52 10.4 0.0 3.0 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAN04167.1 - 0.0085 16.1 4.5 1.1 9.3 0.1 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN04167.1 - 0.0099 16.1 0.5 1.3 9.4 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 GAN04167.1 - 0.023 14.3 0.2 0.53 9.9 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Radical_SAM PF04055.21 GAN04168.1 - 2.8e-25 89.6 0.0 5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 GAN04168.1 - 5.8e-23 81.0 0.0 1.2e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 GAN04168.1 - 8.8e-20 71.4 0.4 2.6e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin DUF4499 PF14934.6 GAN04169.1 - 1.6e-13 50.8 1.3 3e-13 49.9 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 GAN04169.1 - 5.8e-13 49.3 0.0 8.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) COQ7 PF03232.13 GAN04170.1 - 3.9e-54 183.0 0.0 5.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 GAN04170.1 - 0.095 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Rubrerythrin Pribosyl_synth PF14572.6 GAN04171.1 - 1.5e-39 135.9 1.4 1.9e-32 112.8 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 GAN04171.1 - 6.9e-35 119.5 0.0 2.3e-34 117.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 GAN04171.1 - 3e-14 52.9 0.1 5e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAN04171.1 - 0.0067 15.9 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase YliH PF10799.8 GAN04171.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) WD40 PF00400.32 GAN04172.1 - 1.7e-11 44.5 1.0 0.1 13.5 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Lactonase PF10282.9 GAN04172.1 - 8.8e-05 21.9 0.1 0.00062 19.1 0.0 2.2 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 GAN04172.1 - 0.0003 21.0 0.0 13 6.2 0.0 4.0 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 GAN04172.1 - 0.047 14.0 0.4 7.6 7.0 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Ge1_WD40 PF16529.5 GAN04172.1 - 0.085 11.8 0.0 0.43 9.5 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box-like PF12937.7 GAN04173.1 - 1.5e-08 34.4 0.8 4.8e-08 32.8 0.8 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04173.1 - 2.7e-05 23.9 0.1 2.7e-05 23.9 0.1 2.9 4 0 0 4 4 4 1 F-box domain DUF4490 PF14892.6 GAN04173.1 - 0.028 14.5 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) Codanin-1_C PF15296.6 GAN04173.1 - 0.066 13.3 0.3 2.4 8.2 0.0 2.9 2 1 0 2 2 2 0 Codanin-1 C-terminus RTA1 PF04479.13 GAN04174.1 - 8.8e-36 123.5 11.9 8.8e-36 123.5 11.9 1.9 1 1 1 2 2 2 1 RTA1 like protein Pkinase PF00069.25 GAN04175.1 - 2.2e-68 230.5 0.1 2.7e-68 230.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04175.1 - 3.8e-37 128.0 0.0 5.1e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04175.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN04175.1 - 0.00032 20.7 0.1 0.00085 19.3 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN04175.1 - 0.0019 17.0 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAN04175.1 - 0.0033 16.8 0.8 0.0054 16.1 0.8 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN04175.1 - 0.0038 16.2 0.9 0.0066 15.4 0.9 1.4 1 1 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 GAN04175.1 - 0.015 14.9 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 GAN04175.1 - 0.27 10.8 2.8 1 9.0 2.8 2.0 1 1 0 1 1 1 0 RIO1 family Ysc84 PF04366.12 GAN04176.1 - 1.5e-41 141.1 0.7 2.4e-41 140.5 0.1 1.6 2 1 0 2 2 2 1 Las17-binding protein actin regulator tRNA-synt_2b PF00587.25 GAN04177.1 - 5.2e-34 117.8 0.0 2e-33 115.8 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAN04177.1 - 7.8e-12 45.2 0.1 2.5e-11 43.5 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain Cornichon PF03311.14 GAN04179.1 - 2.2e-44 150.7 4.5 4.5e-44 149.7 4.5 1.5 1 0 0 1 1 1 1 Cornichon protein PAP_assoc PF03828.19 GAN04179.1 - 3.9e-15 55.8 0.1 1.2e-14 54.2 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAN04179.1 - 2.4e-06 27.7 0.0 5.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 GAN04179.1 - 0.023 14.4 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 GAN04179.1 - 0.035 14.2 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-rbx1 PF12678.7 GAN04180.1 - 5.8e-07 29.7 12.3 5.8e-07 29.7 12.3 2.1 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAN04180.1 - 1.6e-05 25.1 21.2 0.011 16.1 17.9 3.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN04180.1 - 0.00025 20.8 8.7 0.00025 20.8 8.7 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN04180.1 - 0.00042 20.3 9.0 0.0011 19.0 9.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4834 PF16118.5 GAN04180.1 - 0.00083 20.3 5.4 0.042 14.8 0.6 3.4 2 2 0 2 2 2 1 Domain of unknown function (DUF4834) zf-C3H2C3 PF17122.5 GAN04180.1 - 0.0055 16.7 9.9 0.018 15.1 9.9 2.0 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4 PF00097.25 GAN04180.1 - 0.033 14.1 17.4 0.026 14.4 12.7 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Neur_chan_memb PF02932.16 GAN04180.1 - 0.066 13.3 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rad50_zn_hook PF04423.14 GAN04180.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 GAN04180.1 - 0.27 10.9 9.7 0.89 9.2 9.7 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ASD2 PF08687.11 GAN04180.1 - 0.31 10.6 1.8 11 5.4 0.0 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Mucin PF01456.17 GAN04180.1 - 0.34 10.9 15.7 0.043 13.8 5.5 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein zf-C2HC_2 PF13913.6 GAN04180.1 - 0.45 10.5 3.6 6.8 6.7 0.3 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_UBOX PF13445.6 GAN04180.1 - 0.69 10.0 11.4 0.32 11.0 6.1 3.0 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_10 PF16685.5 GAN04180.1 - 1.3 9.2 12.8 0.37 10.9 6.3 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 GAN04180.1 - 4.9 7.1 20.8 0.26 11.2 8.5 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FoP_duplication PF13865.6 GAN04180.1 - 5.7 7.6 8.4 14 6.4 8.4 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pex14_N PF04695.13 GAN04180.1 - 7.5 7.2 8.2 5.5 7.6 0.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Acatn PF13000.7 GAN04181.1 - 2.5e-173 577.5 25.4 5.2e-90 302.5 15.6 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MIR PF02815.19 GAN04181.1 - 0.12 12.2 0.5 0.2 11.5 0.5 1.2 1 0 0 1 1 1 0 MIR domain Cren7 PF11520.8 GAN04181.1 - 0.25 11.3 0.9 0.65 10.0 0.9 1.7 1 0 0 1 1 1 0 Chromatin protein Cren7 zf-RING_2 PF13639.6 GAN04182.1 - 1.4e-12 47.7 7.3 2.3e-12 47.0 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN04182.1 - 1.1e-09 37.9 4.5 2.2e-09 36.9 4.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAN04182.1 - 1.2e-07 31.4 7.5 2.1e-07 30.7 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN04182.1 - 4e-07 30.2 3.9 8.2e-07 29.2 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAN04182.1 - 2.1e-06 27.5 6.5 3.6e-06 26.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 GAN04182.1 - 0.0002 21.3 0.0 0.00052 20.0 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.6 GAN04182.1 - 0.0011 18.9 2.5 0.0011 18.9 2.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAN04182.1 - 0.002 17.9 7.8 0.0034 17.2 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN04182.1 - 0.02 14.8 6.0 0.031 14.2 6.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAN04182.1 - 0.029 14.4 2.5 0.065 13.3 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IL11 PF07400.11 GAN04182.1 - 0.059 13.0 1.5 0.46 10.1 0.1 2.2 2 0 0 2 2 2 0 Interleukin 11 UL42 PF17638.2 GAN04182.1 - 0.073 13.0 4.6 0.093 12.7 0.2 2.5 2 0 0 2 2 2 0 HCMV UL42 DUF4381 PF14316.6 GAN04182.1 - 0.1 12.9 0.3 0.1 12.9 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Prok-RING_4 PF14447.6 GAN04182.1 - 0.16 11.9 10.1 0.26 11.2 10.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L26 PF16906.5 GAN04183.1 - 6.3e-36 122.7 3.5 1e-35 122.1 3.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAN04183.1 - 1.4e-10 40.7 2.9 3e-10 39.7 2.9 1.6 1 0 0 1 1 1 1 KOW motif DUF1442 PF07279.11 GAN04183.1 - 0.011 15.0 1.2 0.015 14.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) DUF3736 PF12540.8 GAN04183.1 - 2.2 8.4 5.0 3.1 7.9 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3736) p53-inducible11 PF14936.6 GAN04184.1 - 0.079 13.0 0.5 0.086 12.9 0.5 1.2 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 DUF3681 PF12442.8 GAN04184.1 - 0.78 10.3 7.6 2.3 8.7 1.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) NUP214 PF16755.5 GAN04185.1 - 6.2e-11 42.1 0.1 1.3e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 GAN04185.1 - 0.1 12.9 0.0 1 9.7 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SAP PF02037.27 GAN04187.1 - 5.8e-11 41.9 1.8 1.4e-10 40.7 1.8 1.7 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 GAN04187.1 - 0.16 11.8 10.7 0.19 11.5 0.8 3.5 3 1 0 3 3 3 0 Tho1/MOS11 C-terminal domain DUF3176 PF11374.8 GAN04189.1 - 0.0033 17.6 3.3 0.01 16.0 3.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) ILVD_EDD PF00920.21 GAN04189.1 - 0.13 10.9 0.6 0.23 10.0 0.6 1.3 1 0 0 1 1 1 0 Dehydratase family Pkinase PF00069.25 GAN04190.1 - 2.8e-72 243.2 0.0 6.9e-72 242.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04190.1 - 1.1e-54 185.5 0.0 2e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 GAN04190.1 - 1.3e-16 60.7 0.3 3.5e-16 59.3 0.3 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Kinase-like PF14531.6 GAN04190.1 - 3.4e-07 29.9 0.0 0.00045 19.6 0.0 2.6 1 1 1 2 2 2 2 Kinase-like C1_1 PF00130.22 GAN04190.1 - 0.00062 19.6 10.1 0.0013 18.6 10.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.22 GAN04190.1 - 0.0058 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 RIO1 family CDC24 PF06395.11 GAN04190.1 - 0.0089 16.3 0.1 0.025 14.8 0.1 1.7 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 GAN04190.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain Zn_ribbon_17 PF17120.5 GAN04190.1 - 0.18 11.5 7.0 0.34 10.6 7.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 GAN04190.1 - 0.44 10.7 6.0 1.7 8.8 6.0 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger Acetyltransf_1 PF00583.25 GAN04191.1 - 5.3e-14 52.5 0.0 6.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN04191.1 - 2.7e-13 50.0 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN04191.1 - 2.2e-09 37.6 0.0 3.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAN04191.1 - 2.2e-08 34.4 0.1 2.8e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAN04191.1 - 1.5e-05 25.1 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAN04191.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAN04191.1 - 0.0037 17.9 0.0 0.0043 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Homeodomain PF00046.29 GAN04192.1 - 1.5e-16 60.0 3.9 1.5e-16 60.0 3.9 1.8 2 0 0 2 2 2 1 Homeodomain DEAD PF00270.29 GAN04193.1 - 9.3e-36 123.2 0.5 1.9e-35 122.2 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN04193.1 - 4.1e-24 85.1 0.0 1.9e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN04193.1 - 7e-10 39.2 0.0 7e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAN04193.1 - 0.013 14.8 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 GAN04193.1 - 0.014 15.7 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAN04193.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain LicD PF04991.13 GAN04193.1 - 0.046 13.9 3.2 0.093 12.9 3.2 1.4 1 0 0 1 1 1 0 LicD family Band_3_cyto PF07565.13 GAN04193.1 - 3.7 7.3 6.8 20 4.9 0.0 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain zf-C2H2_jaz PF12171.8 GAN04194.1 - 1.3e-09 38.1 5.4 2.4e-09 37.2 5.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SYF2 PF08231.12 GAN04194.1 - 0.0055 17.1 2.4 0.0086 16.5 2.4 1.3 1 1 0 1 1 1 1 SYF2 splicing factor zf-C2H2_2 PF12756.7 GAN04194.1 - 0.0076 16.6 2.1 0.0076 16.6 2.1 1.7 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAN04194.1 - 0.025 15.0 4.1 0.045 14.1 4.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAN04194.1 - 6.1 7.5 7.9 0.96 10.0 4.0 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type YqeY PF09424.10 GAN04195.1 - 0.11 12.6 1.9 0.65 10.1 2.0 1.9 1 1 1 2 2 2 0 Yqey-like protein SCO1-SenC PF02630.14 GAN04196.1 - 4.3e-43 146.5 0.2 6.6e-43 145.8 0.2 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 GAN04196.1 - 0.0002 21.3 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family DUF4381 PF14316.6 GAN04196.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) F-box-like PF12937.7 GAN04197.1 - 0.00018 21.3 0.0 0.00053 19.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04197.1 - 0.0033 17.3 0.4 0.033 14.1 0.0 2.8 3 0 0 3 3 3 1 F-box domain DUF5640 PF18692.1 GAN04197.1 - 0.11 12.5 0.2 0.41 10.7 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5640) Zn_clus PF00172.18 GAN04198.1 - 7.3e-10 38.8 13.4 1.5e-09 37.8 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPMT PF05724.11 GAN04199.1 - 1.9e-32 112.7 0.1 6.2e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 GAN04199.1 - 0.00035 21.2 0.0 0.0015 19.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN04199.1 - 0.0042 16.9 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN04199.1 - 0.035 14.9 0.0 0.39 11.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAN04199.1 - 0.044 14.4 0.0 0.28 11.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 GAN04200.1 - 1.8e-74 249.8 0.1 3.1e-74 249.1 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 GAN04200.1 - 0.00015 21.5 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 GAN04200.1 - 0.00098 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 GAN04200.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PID PF00640.23 GAN04200.1 - 0.022 14.8 0.1 0.059 13.4 0.1 1.7 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Methyltransf_25 PF13649.6 GAN04200.1 - 0.037 14.7 0.0 0.15 12.8 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 GAN04200.1 - 0.078 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain RNB PF00773.19 GAN04201.1 - 1.1e-56 192.6 0.0 2.8e-56 191.2 0.0 1.7 1 1 0 1 1 1 1 RNB domain DUF1024 PF06260.12 GAN04201.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) GNVR PF13807.6 GAN04203.1 - 0.031 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase PPR_2 PF13041.6 GAN04204.1 - 1.7e-11 44.1 1.9 7.6e-09 35.6 0.5 4.0 3 1 1 4 4 4 1 PPR repeat family PPR PF01535.20 GAN04204.1 - 1.9e-07 30.9 0.0 2.1 8.8 0.0 4.9 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 GAN04204.1 - 0.00017 21.0 0.6 0.0011 18.4 0.3 2.0 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAN04204.1 - 0.0053 16.8 3.7 0.082 13.0 0.4 2.5 1 1 2 3 3 3 2 Pentatricopeptide repeat domain Vps55 PF04133.14 GAN04204.1 - 0.0062 16.5 0.5 0.01 15.7 0.5 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Melibiase_2 PF16499.5 GAN04204.1 - 0.039 13.1 0.3 0.099 11.8 0.1 1.7 2 0 0 2 2 2 0 Alpha galactosidase A FAM86 PF14904.6 GAN04204.1 - 0.13 12.3 3.3 3.2 7.9 0.1 3.5 3 1 0 4 4 4 0 Family of unknown function PPR_1 PF12854.7 GAN04204.1 - 5.8 6.7 12.2 1.3 8.8 0.1 4.2 6 0 0 6 6 6 0 PPR repeat MKT1_C PF12246.8 GAN04206.1 - 1.5e-68 230.6 2.2 2.5e-68 229.9 2.2 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 GAN04206.1 - 5.5e-34 116.4 0.4 2.1e-33 114.5 0.2 2.1 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 GAN04206.1 - 2e-07 31.4 0.0 6.7e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAN04206.1 - 0.00062 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region tRNA_SAD PF07973.14 GAN04207.1 - 1.2e-06 28.5 0.2 3.8e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 GAN04207.1 - 4.6e-05 22.1 1.3 0.003 16.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (A) DHHA1 PF02272.19 GAN04207.1 - 0.00038 20.9 2.8 0.00076 19.9 2.8 1.5 1 0 0 1 1 1 1 DHHA1 domain ApoLp-III PF07464.11 GAN04207.1 - 0.0072 16.4 1.4 0.014 15.4 1.4 1.4 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) PocR PF10114.9 GAN04207.1 - 0.078 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR CBS PF00571.28 GAN04208.1 - 2.2e-12 47.2 0.1 0.0048 17.3 0.0 3.4 3 0 0 3 3 3 3 CBS domain XRCC4 PF06632.12 GAN04209.1 - 0.0086 15.0 7.7 0.01 14.7 7.7 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Tektin PF03148.14 GAN04209.1 - 0.066 11.9 19.1 0.15 10.8 1.2 2.2 1 1 0 2 2 2 0 Tektin family bZIP_1 PF00170.21 GAN04209.1 - 0.38 10.9 19.6 2.3 8.4 12.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor Exonuc_VII_L PF02601.15 GAN04209.1 - 0.42 10.1 7.2 0.54 9.8 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 GAN04209.1 - 0.55 9.5 23.5 2.3 7.5 23.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.13 GAN04209.1 - 0.6 10.2 14.7 1.9 8.6 7.2 3.6 2 2 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TMF_DNA_bd PF12329.8 GAN04209.1 - 0.64 10.1 21.2 0.084 12.9 12.9 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 GAN04209.1 - 0.99 7.2 9.6 1.3 6.8 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 GAN04209.1 - 0.99 9.5 17.3 2.3 8.4 5.9 3.2 2 1 1 3 3 3 0 Basic region leucine zipper DUF4140 PF13600.6 GAN04209.1 - 1.3 9.5 7.4 2.5 8.6 2.6 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.9 GAN04209.1 - 1.6 8.6 21.2 0.98 9.3 0.7 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain HAGH_C PF16123.5 GAN04209.1 - 1.6 9.3 8.1 8.1 7.0 6.8 2.4 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus PRKG1_interact PF15898.5 GAN04209.1 - 1.9 9.5 17.6 0.97 10.4 14.5 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 GAN04209.1 - 2.7 7.8 20.7 2.4 8.0 8.5 3.2 1 1 2 3 3 3 0 Septum formation initiator Arc_PepC_II PF06847.11 GAN04209.1 - 3.4 8.2 4.9 6.1 7.4 3.5 2.1 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DUF4200 PF13863.6 GAN04209.1 - 5.8 7.3 22.6 11 6.5 22.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Nrap_D5 PF17406.2 GAN04211.1 - 1.3e-56 190.9 3.4 5.8e-55 185.5 1.6 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 GAN04211.1 - 7.5e-51 172.5 0.6 2.4e-50 170.9 0.1 2.0 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 GAN04211.1 - 4.6e-48 163.3 0.1 9.6e-48 162.3 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 GAN04211.1 - 3.4e-47 160.0 1.9 9e-44 148.9 0.4 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 GAN04211.1 - 1.7e-43 148.3 0.2 6.7e-43 146.4 0.2 2.1 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 GAN04211.1 - 1.2e-27 96.8 0.0 4.7e-27 94.8 0.0 2.1 1 0 0 1 1 1 1 Nrap protein domain 6 Med5 PF08689.10 GAN04211.1 - 0.01 13.7 1.1 0.011 13.5 0.3 1.4 1 1 0 1 1 1 0 Mediator complex subunit Med5 HWE_HK PF07536.14 GAN04211.1 - 0.02 15.6 0.2 0.063 14.0 0.2 1.8 1 0 0 1 1 1 0 HWE histidine kinase Nop PF01798.18 GAN04212.1 - 1.7e-85 286.1 0.3 1.7e-85 286.1 0.3 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAN04212.1 - 1.8e-21 76.2 1.3 1.8e-21 76.2 1.3 2.9 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF3408 PF11888.8 GAN04212.1 - 0.74 10.0 17.9 1.8 8.7 17.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RSN1_7TM PF02714.15 GAN04213.1 - 9.5e-65 218.6 32.7 9.5e-65 218.6 32.7 2.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAN04213.1 - 9.8e-40 135.9 5.5 9.8e-40 135.9 5.5 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAN04213.1 - 5.1e-29 101.7 3.8 1.7e-28 100.1 0.0 3.1 3 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter TLP-20 PF06088.11 GAN04213.1 - 0.028 14.3 0.5 2 8.3 0.4 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2514 PF10721.9 GAN04213.1 - 3 7.9 14.6 0.11 12.5 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) AMP-binding PF00501.28 GAN04214.1 - 5.4e-44 150.5 0.0 8.3e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAN04214.1 - 3.1e-08 33.4 3.3 6e-08 32.5 3.3 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAN04214.1 - 0.0007 20.5 0.0 0.0018 19.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NADH_dh_m_C1 PF15088.6 GAN04214.1 - 0.45 10.2 4.2 1.1 9.0 4.2 1.6 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial SAP PF02037.27 GAN04215.1 - 0.0079 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain LEM PF03020.15 GAN04215.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 LEM domain Acyl-CoA_dh_1 PF00441.24 GAN04216.1 - 5.7e-41 140.2 0.0 9.7e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAN04216.1 - 7.3e-37 126.5 0.0 2.2e-36 125.0 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Peptidase_M28 PF04389.17 GAN04216.1 - 5.5e-36 124.1 0.1 8.3e-36 123.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Acyl-CoA_dh_M PF02770.19 GAN04216.1 - 5.8e-26 90.5 0.0 1.2e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAN04216.1 - 3.5e-13 50.0 0.0 5.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M20 PF01546.28 GAN04216.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3974 PF13120.6 GAN04216.1 - 0.053 13.6 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) TPPK_C PF12555.8 GAN04216.1 - 6.5 6.9 6.0 4.6 7.4 0.0 3.3 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal GFA PF04828.14 GAN04217.1 - 4.4e-10 39.8 1.3 4.4e-10 39.8 1.3 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_16 PF00722.21 GAN04218.1 - 6.3e-20 71.4 0.2 1.2e-19 70.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 zf-RING_11 PF17123.5 GAN04219.1 - 2.2e-11 43.3 3.7 4.8e-11 42.2 3.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAN04219.1 - 1.1e-10 41.7 2.3 1.7e-10 41.1 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN04219.1 - 3.3e-08 33.2 1.5 5.3e-08 32.6 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN04219.1 - 3.1e-07 30.1 1.6 4.9e-07 29.5 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN04219.1 - 9.1e-06 25.9 2.5 2.1e-05 24.7 2.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAN04219.1 - 3.8e-05 23.6 1.1 3.8e-05 23.6 1.1 1.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAN04219.1 - 0.00074 19.4 1.2 0.0012 18.8 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 GAN04219.1 - 0.0033 17.6 1.2 0.0067 16.6 1.2 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain DUF2681 PF10883.8 GAN04219.1 - 0.0033 17.8 0.2 0.005 17.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) MPM1 PF17234.2 GAN04219.1 - 0.0034 17.7 0.4 0.0041 17.4 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 zf-HC5HC2H_2 PF13832.6 GAN04219.1 - 0.0095 16.1 1.8 0.013 15.6 1.8 1.4 1 1 0 1 1 1 1 PHD-zinc-finger like domain Vps39_2 PF10367.9 GAN04219.1 - 0.011 16.1 0.5 0.013 15.9 0.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-HC5HC2H PF13771.6 GAN04219.1 - 0.011 15.9 2.3 0.015 15.5 2.1 1.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 GAN04219.1 - 0.012 15.2 0.6 0.019 14.6 0.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAN04219.1 - 0.027 14.6 0.8 0.075 13.2 0.8 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 GAN04219.1 - 0.03 14.2 0.9 0.054 13.4 0.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 GAN04219.1 - 0.067 13.2 4.4 0.4 10.8 4.4 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sds3 PF08598.11 GAN04220.1 - 4.2e-17 62.9 16.0 4.2e-17 62.9 16.0 1.6 2 0 0 2 2 2 1 Sds3-like LBR_tudor PF09465.10 GAN04221.1 - 4.2e-05 23.3 0.0 8.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 GAN04221.1 - 8.4e-05 22.7 0.4 0.00023 21.3 0.2 1.8 1 1 1 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 GAN04221.1 - 0.00021 21.3 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) SMN PF06003.12 GAN04221.1 - 0.00029 20.2 0.2 0.00041 19.7 0.2 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Tudor_3 PF18115.1 GAN04221.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 GAN04221.1 - 0.02 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain TUDOR PF00567.24 GAN04221.1 - 0.025 14.6 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Tudor domain DMAP1 PF05499.12 GAN04221.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.8 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Methyltransf_23 PF13489.6 GAN04222.1 - 9e-19 67.9 0.0 1.7e-18 67.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN04222.1 - 4.4e-17 62.5 0.0 7.2e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN04222.1 - 5.8e-13 49.4 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN04222.1 - 2.4e-10 40.4 0.0 4.2e-10 39.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN04222.1 - 3.6e-10 40.5 0.0 7.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAN04222.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 GAN04222.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 GAN04222.1 - 0.00099 18.5 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 GAN04222.1 - 0.0033 16.9 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAN04222.1 - 0.0085 15.7 0.0 0.026 14.1 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAN04222.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 GAN04222.1 - 0.036 13.5 0.0 0.053 12.9 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 GAN04222.1 - 0.15 11.2 0.0 0.41 9.7 0.0 1.6 1 1 0 1 1 1 0 DREV methyltransferase Pkinase PF00069.25 GAN04223.1 - 1.6e-78 263.7 0.0 2.1e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04223.1 - 4e-36 124.6 0.0 5.4e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04223.1 - 5e-05 22.8 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN04223.1 - 9.6e-05 21.3 0.0 0.0004 19.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAN04223.1 - 0.013 15.4 0.0 0.11 12.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAN04223.1 - 0.026 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 GAN04223.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 GAN04223.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PACT_coil_coil PF10495.9 GAN04223.1 - 0.12 13.0 0.7 0.26 11.9 0.1 1.9 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Mod_r PF07200.13 GAN04225.1 - 5.4e-28 97.9 14.6 5.4e-28 97.9 14.6 8.1 5 2 1 7 7 7 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.13 GAN04225.1 - 0.003 17.4 0.2 0.0096 15.8 0.2 1.9 1 0 0 1 1 1 1 UEV domain TPR_7 PF13176.6 GAN04225.1 - 0.0088 16.0 0.1 0.076 13.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Rad60-SLD PF11976.8 GAN04225.1 - 0.028 14.2 0.2 0.028 14.2 0.2 4.1 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like DR2241 PF18069.1 GAN04225.1 - 0.11 12.3 1.6 0.34 10.8 1.6 1.8 1 0 0 1 1 1 0 DR2241 stabilising domain Amidinotransf PF02274.17 GAN04228.1 - 2.9e-20 72.7 0.8 1.5e-17 63.7 0.0 2.0 1 1 1 2 2 2 2 Amidinotransferase Tfb5 PF06331.12 GAN04228.1 - 0.03 14.3 2.0 0.075 13.0 0.1 2.5 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 PhosphMutase PF10143.9 GAN04228.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase TLD PF07534.16 GAN04229.1 - 1.1e-39 135.8 0.4 2.5e-39 134.7 0.4 1.6 1 0 0 1 1 1 1 TLD Rav1p_C PF12234.8 GAN04230.1 - 1.8e-197 657.7 1.3 3.8e-197 656.6 1.3 1.5 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 GAN04230.1 - 2.2e-07 31.4 13.4 1.6e-05 25.5 0.1 6.8 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04230.1 - 0.0011 19.2 0.1 0.039 14.2 0.0 3.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAN04230.1 - 0.038 12.7 0.1 0.038 12.7 0.1 2.3 3 0 0 3 3 3 0 Nup133 N terminal like YmzC PF14157.6 GAN04230.1 - 0.053 13.6 5.8 14 5.8 0.3 5.0 5 0 0 5 5 5 0 YmzC-like protein RRM_1 PF00076.22 GAN04231.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_circ_N PF07157.12 GAN04232.1 - 0.093 13.1 0.7 8.4 6.9 0.1 2.5 1 1 1 2 2 2 0 DNA circularisation protein N-terminus AP1AR PF15745.5 GAN04235.1 - 0.22 11.1 5.7 0.76 9.4 5.7 1.9 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein PAS PF00989.25 GAN04236.1 - 1.3e-05 25.1 0.0 4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 GAN04236.1 - 2e-05 24.6 11.2 2e-05 24.6 11.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IF3_C PF00707.22 GAN04237.1 - 8.2 6.5 8.0 54 3.8 0.1 4.1 5 0 0 5 5 5 0 Translation initiation factor IF-3, C-terminal domain Glyco_transf_5 PF08323.11 GAN04238.1 - 7.3e-13 48.8 0.1 3e-12 46.8 0.1 2.1 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GAN04238.1 - 5.6e-12 45.5 0.0 3.2e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN04238.1 - 5e-09 36.7 0.0 1.4e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 CobT PF06213.12 GAN04238.1 - 3.4e-06 26.7 22.9 8.3e-05 22.1 7.0 2.3 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 GAN04238.1 - 0.0012 18.3 27.4 0.0051 16.3 4.1 2.2 2 0 0 2 2 2 2 SDA1 Glyco_trans_4_4 PF13579.6 GAN04238.1 - 0.0019 18.6 0.1 0.0019 18.6 0.1 1.9 2 0 0 2 2 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAN04238.1 - 0.0037 17.3 0.2 0.0099 15.9 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Sigma70_ner PF04546.13 GAN04238.1 - 0.0064 16.4 6.7 0.0064 16.4 6.7 3.0 3 0 0 3 3 3 1 Sigma-70, non-essential region Nop14 PF04147.12 GAN04238.1 - 0.017 13.3 27.2 0.0058 14.9 4.5 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2457 PF10446.9 GAN04238.1 - 0.065 12.4 37.5 0.11 11.7 14.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RNA_pol_Rpc4 PF05132.14 GAN04238.1 - 0.079 13.4 7.1 2.6 8.4 1.2 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Pox_Ag35 PF03286.14 GAN04238.1 - 0.093 12.5 19.8 0.048 13.4 4.2 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CPSF100_C PF13299.6 GAN04238.1 - 0.3 11.2 13.0 2.2 8.4 3.3 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 GAN04238.1 - 0.33 9.4 29.0 0.8 8.1 11.7 2.1 2 0 0 2 2 2 0 Mpp10 protein DUF2052 PF09747.9 GAN04238.1 - 0.37 10.9 27.0 1.5 8.9 11.4 2.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BSP_II PF05432.11 GAN04238.1 - 0.47 10.1 29.2 0.023 14.4 9.7 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 GAN04238.1 - 0.5 9.6 28.2 0.19 11.0 6.7 2.2 2 0 0 2 2 2 0 BUD22 RXT2_N PF08595.11 GAN04238.1 - 0.89 9.6 20.2 0.93 9.5 6.5 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.14 GAN04238.1 - 1.1 7.5 24.6 0.65 8.2 6.5 2.1 2 0 0 2 2 2 0 CDC45-like protein POP1 PF06978.11 GAN04238.1 - 1.5 8.7 8.5 0.071 13.1 1.9 1.9 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 SpoIIIAH PF12685.7 GAN04238.1 - 1.6 8.5 15.3 0.51 10.1 3.6 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Na_trans_assoc PF06512.13 GAN04238.1 - 2.7 8.2 15.0 5.7 7.2 4.0 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated TLP-20 PF06088.11 GAN04238.1 - 2.9 7.8 17.0 1.7 8.5 4.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RRN3 PF05327.11 GAN04238.1 - 2.9 6.3 25.5 1.1 7.7 4.1 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 GAN04238.1 - 3.6 7.9 32.4 6 7.2 11.4 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 GAN04238.1 - 5.5 6.4 13.3 7.2 6.0 4.0 2.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RAB3GAP2_C PF14656.6 GAN04238.1 - 7.1 4.7 9.0 0.53 8.5 0.5 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RPA43_OB PF17875.1 GAN04238.1 - 7.3 7.2 10.7 19 5.9 3.0 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Tub_N PF16322.5 GAN04238.1 - 7.3 6.9 20.6 7.1 7.0 5.2 2.3 2 0 0 2 2 2 0 Tubby N-terminal YL1 PF05764.13 GAN04238.1 - 7.6 6.6 29.5 2 8.5 8.3 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DUF719 PF05334.13 GAN04238.1 - 7.6 6.7 9.3 6.1 7.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) PPP4R2 PF09184.11 GAN04238.1 - 8.4 5.9 28.9 1.7 8.1 8.6 2.3 2 0 0 2 2 2 0 PPP4R2 TFB6 PF17110.5 GAN04238.1 - 9.1 6.0 20.6 2.4 7.9 6.8 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 GAN04238.1 - 9.7 5.4 31.9 3.9 6.7 12.3 2.2 2 0 0 2 2 2 0 NOA36 protein INTS2 PF14750.6 GAN04239.1 - 6.9e-07 27.3 3.3 2.9e-06 25.2 3.3 1.7 1 1 0 1 1 1 1 Integrator complex subunit 2 IFNGR1 PF07140.11 GAN04239.1 - 0.26 11.4 2.5 0.52 10.4 2.2 1.8 1 1 0 1 1 1 0 Interferon gamma receptor (IFNGR1) DUF3425 PF11905.8 GAN04240.1 - 5.4e-16 58.7 0.6 5.4e-16 58.7 0.6 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAN04240.1 - 6.9e-08 32.5 5.8 1.7e-07 31.3 5.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor NRBF2 PF08961.10 GAN04240.1 - 0.0012 18.5 5.9 0.0034 17.0 5.9 1.8 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator bZIP_2 PF07716.15 GAN04240.1 - 0.71 10.0 11.1 1.3 9.2 9.6 2.1 1 1 1 2 2 2 0 Basic region leucine zipper DUF5094 PF17015.5 GAN04240.1 - 1.9 8.6 6.0 5.2 7.1 6.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DUF4407 PF14362.6 GAN04240.1 - 3.4 7.0 4.4 6.7 6.0 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 GAN04240.1 - 4.1 7.5 10.9 0.028 14.4 1.9 2.0 2 0 0 2 2 2 0 Short coiled-coil protein YjbH PF06082.11 GAN04240.1 - 9.1 5.0 10.1 18 4.0 10.1 1.4 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Guanylate_kin PF00625.21 GAN04241.1 - 1.4e-63 213.9 0.0 1.6e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 GAN04241.1 - 7.8e-06 26.1 0.0 0.0001 22.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAN04241.1 - 1.5e-05 25.5 0.0 3.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN04241.1 - 3.3e-05 24.2 0.0 5.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAN04241.1 - 6.3e-05 23.5 0.0 7.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 GAN04241.1 - 6.5e-05 23.0 0.0 0.00013 22.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAN04241.1 - 0.00019 21.9 0.0 0.00047 20.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAN04241.1 - 0.00067 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAN04241.1 - 0.00078 19.1 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GAN04241.1 - 0.0017 18.9 0.2 0.0039 17.7 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAN04241.1 - 0.0026 17.8 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 GAN04241.1 - 0.0042 16.7 0.3 0.021 14.4 0.0 2.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 GAN04241.1 - 0.0044 16.1 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 GAN04241.1 - 0.0055 16.6 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Thymidylate_kin PF02223.17 GAN04241.1 - 0.0059 16.3 0.0 0.92 9.1 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase ATPase_2 PF01637.18 GAN04241.1 - 0.0076 16.2 0.1 0.0098 15.8 0.1 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAN04241.1 - 0.0077 16.5 0.1 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 GAN04241.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NACHT PF05729.12 GAN04241.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 GAN04241.1 - 0.014 15.8 0.1 0.05 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAN04241.1 - 0.015 15.7 0.1 0.035 14.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase DUF2075 PF09848.9 GAN04241.1 - 0.015 14.5 0.0 0.051 12.8 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) dNK PF01712.19 GAN04241.1 - 0.018 14.9 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.6 GAN04241.1 - 0.027 14.2 0.1 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAN04241.1 - 0.036 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAN04241.1 - 0.055 12.7 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 GAN04241.1 - 0.085 12.1 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 GAN04241.1 - 0.095 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 GAN04241.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 GAN04241.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase WD40 PF00400.32 GAN04243.1 - 6.6e-34 115.4 20.9 3.3e-06 27.7 0.5 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 GAN04243.1 - 2.2e-16 59.6 8.5 5.9e-05 21.9 0.6 5.2 2 1 3 5 5 5 5 Nucleoporin Nup120/160 WD40_like PF17005.5 GAN04243.1 - 6.1e-13 48.8 0.0 5e-08 32.6 0.0 3.1 1 1 2 3 3 3 3 WD40-like domain F-box-like PF12937.7 GAN04243.1 - 2.8e-10 39.9 0.6 5.7e-10 38.9 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04243.1 - 1.8e-09 37.2 0.6 4.3e-09 36.0 0.6 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 GAN04243.1 - 3.4e-07 30.5 2.8 0.31 11.4 0.2 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 GAN04243.1 - 2.4e-05 24.2 0.1 4.9e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 GAN04243.1 - 0.00015 21.4 1.8 0.048 13.2 0.2 2.9 2 1 1 3 3 3 2 PQQ-like domain PALB2_WD40 PF16756.5 GAN04243.1 - 0.00068 18.7 3.1 0.058 12.3 0.0 3.9 3 2 1 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 GAN04243.1 - 0.031 13.3 4.8 1.8 7.4 0.0 3.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Thiolase_N PF00108.23 GAN04244.1 - 2.2e-76 256.7 2.4 3e-76 256.2 1.8 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN04244.1 - 7.6e-46 154.8 0.1 1.6e-45 153.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 GAN04244.1 - 0.053 13.7 0.0 0.19 11.9 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal tRNA-synt_1b PF00579.25 GAN04246.1 - 2.8e-73 246.8 0.0 3.3e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Exo_endo_phos PF03372.23 GAN04247.1 - 3.2e-09 36.7 0.3 5.3e-09 36.0 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CAP_assoc_N PF14504.6 GAN04247.1 - 0.043 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 CAP-associated N-terminal ALAD PF00490.21 GAN04248.1 - 7e-125 416.4 0.0 8.4e-125 416.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase F-box-like PF12937.7 GAN04249.1 - 2.1e-06 27.5 0.1 5e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04249.1 - 0.00021 21.1 0.1 0.00079 19.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain Acetyltransf_1 PF00583.25 GAN04250.1 - 8.6e-10 38.9 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN04250.1 - 5.2e-08 32.9 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN04250.1 - 7.3e-07 29.5 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN04250.1 - 0.00043 20.2 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein CREPT PF16566.5 GAN04250.1 - 0.063 13.5 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Acetyltransf_9 PF13527.7 GAN04250.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAN04250.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RCC1 PF00415.18 GAN04251.1 - 4.8e-29 100.7 6.5 2.9e-07 31.0 0.1 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAN04251.1 - 4.6e-17 62.3 2.7 1.5e-07 31.6 0.1 2.8 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 GAN04251.1 - 5.5e-12 46.0 0.2 5.8e-05 23.6 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN04251.1 - 1e-11 45.3 0.0 3.8e-11 43.4 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 GAN04251.1 - 2.2e-10 40.0 8.1 6e-09 35.5 0.2 4.4 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.30 GAN04251.1 - 5.4e-09 36.1 0.0 0.0051 17.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GAN04251.1 - 1.8e-07 30.9 0.5 0.02 15.4 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAN04251.1 - 5.7e-05 23.3 0.2 0.0006 20.1 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF2407_C PF13373.6 GAN04251.1 - 0.69 10.1 4.4 0.76 10.0 0.1 3.0 4 0 0 4 4 4 0 DUF2407 C-terminal domain Codanin-1_C PF15296.6 GAN04251.1 - 2 8.5 5.9 1.6 8.8 0.7 3.3 2 0 0 2 2 2 0 Codanin-1 C-terminus NAD_binding_10 PF13460.6 GAN04252.1 - 1.5e-07 31.5 0.1 3.4e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN04252.1 - 0.0056 16.3 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family FeoB_Cyto PF17910.1 GAN04252.1 - 0.019 15.5 0.1 0.045 14.3 0.1 1.6 1 0 0 1 1 1 0 FeoB cytosolic helical domain Syja_N PF02383.18 GAN04253.1 - 2e-87 293.5 2.8 1.7e-86 290.4 2.8 2.1 1 1 0 1 1 1 1 SacI homology domain CsbD PF05532.12 GAN04254.1 - 2.4e-13 49.8 14.9 9.5e-10 38.2 5.1 2.0 1 1 1 2 2 2 2 CsbD-like YvrJ PF12841.7 GAN04255.1 - 0.25 10.9 6.4 3.3 7.3 0.8 2.5 2 0 0 2 2 2 0 YvrJ protein family Gpr1_Fun34_YaaH PF01184.19 GAN04255.1 - 1.8 8.1 13.5 1 9.0 9.6 1.9 1 1 1 2 2 2 0 GPR1/FUN34/yaaH family Metallophos PF00149.28 GAN04256.1 - 7.7e-10 39.6 2.0 1.4e-09 38.8 2.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M24 PF00557.24 GAN04257.1 - 6e-19 68.6 0.0 7.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Glycohydro_20b2 PF14845.6 GAN04257.1 - 0.15 12.7 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like NODP PF07684.12 GAN04257.1 - 0.18 12.0 0.7 14 5.9 0.1 2.5 2 0 0 2 2 2 0 NOTCH protein C2 PF00168.30 GAN04258.1 - 3e-13 49.9 0.1 6.5e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 C2 domain Nop14 PF04147.12 GAN04258.1 - 0.26 9.5 22.7 0.33 9.1 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family EIF4E-T PF10477.9 GAN04258.1 - 0.68 8.7 23.4 1.1 8.0 23.4 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Hid1 PF12722.7 GAN04258.1 - 0.95 7.5 11.8 1.4 7.0 11.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MctB PF11382.8 GAN04258.1 - 0.99 9.1 6.5 0.084 12.6 1.3 1.8 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB DUF2076 PF09849.9 GAN04258.1 - 2.6 8.0 19.1 6.2 6.8 19.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SLC12 PF03522.15 GAN04258.1 - 8.7 5.2 15.9 14 4.6 15.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RrnaAD PF00398.20 GAN04259.1 - 1.5e-28 99.6 0.0 2e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase VCBS PF13517.6 GAN04260.1 - 3e-31 107.8 13.0 1.6e-10 41.4 0.6 5.6 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAN04260.1 - 1.7e-10 40.8 27.4 0.0025 17.9 0.2 7.3 7 0 0 7 7 7 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 GAN04260.1 - 4.5e-05 22.9 2.1 2.3 7.6 0.0 4.8 4 2 0 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region DUF4690 PF15756.5 GAN04260.1 - 0.0041 17.7 2.2 0.094 13.3 1.0 3.0 3 0 0 3 3 3 1 Small Novel Rich in Cartilage DnaJ PF00226.31 GAN04261.1 - 9.1e-24 83.4 2.2 1.3e-23 82.8 0.4 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 GAN04261.1 - 2.2e-10 40.5 6.9 1.4e-09 38.0 2.5 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN04261.1 - 2e-07 31.2 2.4 2e-07 31.2 2.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAN04261.1 - 3.9e-05 23.9 9.9 0.016 15.5 0.3 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN04261.1 - 0.0001 22.8 2.1 0.43 11.5 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN04261.1 - 0.0013 19.0 4.5 0.68 10.5 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-RVT PF13966.6 GAN04261.1 - 0.47 11.2 3.2 0.25 12.1 0.5 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase zf-C2H2_3rep PF18868.1 GAN04261.1 - 7 7.3 7.8 4.2 8.1 0.2 3.2 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats MASE2 PF05230.11 GAN04262.1 - 0.11 12.6 0.3 0.61 10.2 0.0 1.9 1 1 1 2 2 2 0 MASE2 domain bZIP_2 PF07716.15 GAN04263.1 - 2.4e-11 43.5 8.9 4.4e-11 42.7 8.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN04263.1 - 0.0053 16.8 8.4 0.012 15.7 8.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor MRPL52 PF18699.1 GAN04263.1 - 0.015 15.5 2.4 0.027 14.7 2.4 1.4 1 0 0 1 1 1 0 Mitoribosomal protein mL52 XhlA PF10779.9 GAN04263.1 - 0.13 12.5 3.1 0.26 11.5 3.1 1.5 1 0 0 1 1 1 0 Haemolysin XhlA YabA PF06156.13 GAN04263.1 - 1.5 9.5 4.7 2.6 8.7 4.3 1.7 1 1 0 1 1 1 0 Initiation control protein YabA C2 PF00168.30 GAN04264.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain G0-G1_switch_2 PF15103.6 GAN04264.1 - 9.5 6.7 12.5 59 4.2 0.0 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 TMEM43 PF07787.12 GAN04265.1 - 1.2 8.4 6.5 3.5 6.9 6.5 1.7 1 0 0 1 1 1 0 Transmembrane protein 43 G-alpha PF00503.20 GAN04266.1 - 6.3e-107 357.8 5.6 8.1e-107 357.4 5.6 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Pyrophosphatase PF00719.19 GAN04266.1 - 4.1e-57 192.5 0.2 7.1e-57 191.7 0.2 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase Arf PF00025.21 GAN04266.1 - 1e-12 47.9 0.2 4.7e-08 32.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family SMP_C2CD2L PF18696.1 GAN04266.1 - 0.024 14.5 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain Roc PF08477.13 GAN04266.1 - 0.045 14.0 0.5 0.99 9.6 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAN04266.1 - 0.068 12.5 0.4 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Malate_synthase PF01274.22 GAN04267.1 - 3.7e-225 748.1 0.0 4.2e-225 748.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 GAN04267.1 - 0.012 14.8 0.0 0.041 13.0 0.0 1.8 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Peptidase_M48_N PF16491.5 GAN04268.1 - 1.7e-63 213.8 12.2 1.7e-63 213.8 12.2 2.3 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GAN04268.1 - 8.2e-48 162.8 0.4 1.6e-47 161.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 GAN04268.1 - 1.2e-05 24.7 1.0 8.7e-05 21.9 0.5 2.4 2 1 1 3 3 3 1 BlaR1 peptidase M56 SprT-like PF10263.9 GAN04268.1 - 0.0055 16.5 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 SprT-like family UPF0114 PF03350.16 GAN04268.1 - 0.031 14.5 1.6 0.031 14.5 1.6 2.8 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 WD40 PF00400.32 GAN04269.1 - 8e-10 39.2 11.0 0.00065 20.5 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Ins_P5_2-kin PF06090.12 GAN04270.1 - 6.6e-68 229.6 0.1 7.5e-68 229.4 0.1 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Flu_PB1 PF00602.17 GAN04270.1 - 0.092 10.8 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 YEATS PF03366.16 GAN04271.1 - 1.1e-16 60.5 0.8 2.3e-16 59.5 0.8 1.6 1 0 0 1 1 1 1 YEATS family BET PF17035.5 GAN04271.1 - 0.00013 22.1 1.1 0.00013 22.1 1.1 2.1 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation zf-C3HC4_3 PF13920.6 GAN04272.1 - 1.1e-05 25.2 7.5 1.1e-05 25.2 7.5 3.9 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 GAN04272.1 - 0.0069 16.8 0.0 0.0069 16.8 0.0 6.7 7 1 0 7 7 7 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN04272.1 - 0.07 14.0 0.1 0.07 14.0 0.1 6.7 8 2 0 8 8 8 0 C2H2-type zinc finger CCDC106 PF15794.5 GAN04272.1 - 6.7 6.3 26.2 0.61 9.8 10.8 3.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 Perilipin PF03036.16 GAN04273.1 - 0.0036 16.4 16.1 0.024 13.7 0.1 3.1 1 1 2 3 3 3 2 Perilipin family PET10 PF17316.2 GAN04273.1 - 0.034 13.7 2.1 0.049 13.1 2.0 1.5 1 1 0 1 1 1 0 Petite colonies protein 10 DCA16 PF15349.6 GAN04273.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 FH2 PF02181.23 GAN04274.1 - 1.3e-74 251.5 9.2 1.3e-74 251.5 9.2 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAN04274.1 - 4.4e-19 68.8 0.1 4.4e-19 68.8 0.1 2.6 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAN04274.1 - 6.5e-07 29.2 0.1 6.5e-07 29.2 0.1 3.0 3 1 1 4 4 4 1 Diaphanous FH3 Domain Mito_fiss_reg PF05308.11 GAN04274.1 - 0.063 13.4 5.4 0.17 11.9 5.4 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator BCDHK_Adom3 PF10436.9 GAN04274.1 - 0.096 12.5 1.5 1.7 8.5 0.7 2.8 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3361 PF11841.8 GAN04274.1 - 0.28 11.1 4.1 28 4.6 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Syntaxin_2 PF14523.6 GAN04274.1 - 1.6 9.1 8.0 1.6 9.2 0.0 3.7 3 0 0 3 3 3 0 Syntaxin-like protein RPN7 PF10602.9 GAN04275.1 - 3.9e-60 202.5 1.1 6.8e-60 201.7 1.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAN04275.1 - 1.1e-13 51.6 0.1 4.7e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 GAN04275.1 - 0.018 15.1 0.3 0.044 13.8 0.1 1.8 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family HTH_DeoR PF08220.12 GAN04275.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TPR_2 PF07719.17 GAN04275.1 - 0.057 13.6 0.8 0.58 10.4 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.13 GAN04275.1 - 0.092 12.8 2.0 0.24 11.5 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TPR_16 PF13432.6 GAN04275.1 - 0.19 12.4 1.6 1.7 9.3 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN04275.1 - 0.99 10.2 5.6 0.63 10.8 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN04275.1 - 2.9 8.3 8.8 0.2 12.0 1.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN6_N PF18055.1 GAN04276.1 - 1.7e-39 134.7 1.7 1.7e-39 134.7 1.7 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 GAN04276.1 - 1.7e-19 70.3 0.1 1.7e-19 70.3 0.1 2.8 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 GAN04276.1 - 4.6e-12 45.5 1.5 1.2e-11 44.1 1.5 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 GAN04276.1 - 0.00031 20.5 5.7 4 7.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Mce4_CUP1 PF11887.8 GAN04276.1 - 0.022 14.2 0.2 0.041 13.3 0.2 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DDRGK PF09756.9 GAN04276.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 DDRGK domain TPR_16 PF13432.6 GAN04276.1 - 0.43 11.3 4.3 1.2 9.8 0.7 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 GAN04276.1 - 0.44 10.2 4.2 0.52 10.0 1.2 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Isochorismatase PF00857.20 GAN04277.1 - 4.8e-16 59.4 0.0 6.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family XG_FTase PF03254.13 GAN04279.1 - 6.5e-09 34.9 0.1 0.00056 18.7 0.0 2.9 3 0 0 3 3 3 2 Xyloglucan fucosyltransferase OppC_N PF12911.7 GAN04279.1 - 0.0086 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Cpn60_TCP1 PF00118.24 GAN04281.1 - 1e-149 499.3 14.3 1.2e-149 499.2 14.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 GAN04281.1 - 0.04 13.4 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 Telomere recombination Hormone_3 PF00159.18 GAN04282.1 - 0.037 14.1 0.5 0.068 13.3 0.5 1.4 1 0 0 1 1 1 0 Pancreatic hormone peptide NUDIX PF00293.28 GAN04283.1 - 3.6e-16 59.4 0.3 4.4e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain NOG1_N PF17835.1 GAN04284.1 - 5.1e-56 189.1 2.4 5.1e-56 189.1 2.4 1.9 2 0 0 2 2 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 GAN04284.1 - 1.5e-28 98.5 1.9 3.9e-28 97.2 1.9 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 GAN04284.1 - 2.4e-28 97.7 2.0 3e-28 97.4 0.2 2.1 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAN04284.1 - 6.8e-19 68.0 0.0 1.7e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN04284.1 - 9.4e-10 38.2 0.0 2.1e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAN04284.1 - 8.9e-05 22.4 0.3 0.3 11.0 0.0 3.2 2 2 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 GAN04284.1 - 0.00051 19.4 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 GAN04284.1 - 0.0012 19.0 0.0 0.013 15.8 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAN04284.1 - 0.0031 17.6 1.2 0.83 9.7 0.0 3.3 2 1 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 GAN04284.1 - 0.011 16.1 0.0 0.06 13.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 GAN04284.1 - 0.021 14.4 4.4 0.11 12.1 0.4 3.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 GAN04284.1 - 0.06 12.8 0.4 0.62 9.4 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein G-alpha PF00503.20 GAN04284.1 - 0.065 12.4 4.2 0.17 11.0 0.3 2.9 2 1 0 3 3 3 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 GAN04284.1 - 0.074 13.1 0.6 0.98 9.5 0.2 2.7 1 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain RhoGAP PF00620.27 GAN04285.1 - 3.5e-38 130.8 0.0 7.8e-38 129.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 GAN04285.1 - 5.5e-22 77.8 52.6 1.4e-09 38.1 6.8 5.1 5 0 0 5 5 5 4 LIM domain ParE_toxin PF05016.15 GAN04286.1 - 0.06 14.0 0.0 0.12 13.0 0.0 1.4 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE NmrA PF05368.13 GAN04288.1 - 0.0032 17.1 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family HsbA PF12296.8 GAN04289.1 - 1.3e-15 57.9 0.1 1.8e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A MFS_1 PF07690.16 GAN04290.1 - 3.3e-48 164.4 31.4 3.9e-48 164.2 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN04290.1 - 2.5e-10 39.8 27.1 8.2e-09 34.8 9.1 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter DUF5058 PF16481.5 GAN04290.1 - 0.039 13.6 8.9 0.13 11.9 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5058) Transgly_assoc PF04226.13 GAN04290.1 - 0.5 10.7 11.9 1.2 9.5 6.6 3.5 3 0 0 3 3 3 0 Transglycosylase associated protein GCV_T PF01571.21 GAN04291.1 - 5e-87 291.5 0.1 7.1e-87 291.0 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain RabGAP-TBC PF00566.18 GAN04291.1 - 8.3e-57 192.3 0.2 8.3e-57 192.3 0.2 2.7 2 1 1 3 3 3 1 Rab-GTPase-TBC domain GCV_T_C PF08669.11 GAN04291.1 - 3.6e-20 71.7 0.3 1e-19 70.2 0.1 1.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 GAN04291.1 - 0.0025 18.0 0.2 0.44 10.7 0.0 2.5 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Cep57_CLD_2 PF14197.6 GAN04291.1 - 0.17 12.0 18.1 0.018 15.1 9.1 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4763 PF15960.5 GAN04291.1 - 0.52 9.6 16.7 1.1 8.5 16.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) TSC22 PF01166.18 GAN04291.1 - 0.77 10.1 10.3 0.081 13.2 2.4 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family LMBR1 PF04791.16 GAN04291.1 - 1 8.2 9.2 1.6 7.5 9.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.11 GAN04291.1 - 3.7 7.7 24.5 1.5 9.0 4.7 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 GAN04291.1 - 5.7 7.4 24.1 1.9 9.0 2.7 3.4 1 1 2 3 3 3 0 Cell division protein ZapB His_Phos_1 PF00300.22 GAN04292.1 - 1.4e-39 135.8 0.0 1.7e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2781 PF10914.8 GAN04293.1 - 7.6e-44 149.7 11.7 8.7e-44 149.5 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) RNB PF00773.19 GAN04294.1 - 2.2e-101 339.5 0.2 2.6e-100 336.0 0.0 2.2 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 GAN04294.1 - 1.8e-17 63.4 0.1 1e-16 61.0 0.1 2.4 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 GAN04294.1 - 9e-14 51.3 0.0 3e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) OB_RNB PF08206.11 GAN04294.1 - 0.018 14.8 0.1 0.043 13.5 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Rrp44_S1 PF17215.3 GAN04294.1 - 0.039 13.9 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 S1 domain Rrp44_CSD1 PF17216.3 GAN04294.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain KI67R PF08065.12 GAN04294.1 - 8.4 7.0 13.6 3.8 8.1 1.0 3.6 3 0 0 3 3 3 0 KI67R (NUC007) repeat Ribosomal_L27e PF01777.18 GAN04295.1 - 7.3e-28 96.7 5.9 1.8e-27 95.5 5.9 1.6 1 0 0 1 1 1 1 Ribosomal L27e protein family Ribosomal_S2 PF00318.20 GAN04295.1 - 1.2e-26 93.4 2.5 1.9e-13 50.1 0.1 2.6 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 GAN04295.1 - 2.2e-06 28.9 15.9 5.7e-06 27.6 15.9 1.7 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus KOW PF00467.29 GAN04295.1 - 0.0012 18.7 0.8 0.0032 17.4 0.8 1.7 1 0 0 1 1 1 1 KOW motif Ras PF00071.22 GAN04296.1 - 1e-59 200.7 0.3 1.5e-59 200.2 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN04296.1 - 1.1e-36 125.7 0.1 1.7e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN04296.1 - 6.4e-15 55.0 0.2 8.5e-15 54.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN04296.1 - 4.1e-05 23.6 0.1 0.0001 22.4 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAN04296.1 - 4.5e-05 23.0 0.1 5.7e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAN04296.1 - 7.7e-05 22.3 0.1 0.00054 19.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN04296.1 - 0.00016 21.7 0.3 0.18 11.7 0.2 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAN04296.1 - 0.0003 20.2 0.2 0.00041 19.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAN04296.1 - 0.006 16.1 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B HEAT PF02985.22 GAN04297.1 - 8.9e-05 22.4 1.6 1.8 9.0 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 GAN04297.1 - 0.028 14.8 0.1 6.2 7.3 0.0 4.6 5 1 0 5 5 5 0 HEAT repeats DUF2017 PF09438.10 GAN04297.1 - 0.09 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) RasGAP PF00616.19 GAN04298.1 - 1.2e-13 51.3 1.6 6e-13 49.0 0.0 2.6 2 1 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAN04298.1 - 2.3e-13 50.5 1.3 2.3e-13 50.5 1.3 2.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 GAN04298.1 - 1.4e-05 25.1 0.4 4.3e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal CRAL_TRIO PF00650.20 GAN04298.1 - 0.0018 18.0 0.9 0.0056 16.4 0.9 1.9 1 0 0 1 1 1 1 CRAL/TRIO domain U3snoRNP10 PF12397.8 GAN04298.1 - 0.11 12.8 1.1 3.1e+02 1.7 0.0 5.0 5 0 0 5 5 5 0 U3 small nucleolar RNA-associated protein 10 XPG_N PF00752.17 GAN04299.1 - 3.4e-15 56.3 0.0 1.1e-13 51.5 0.0 2.6 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 GAN04299.1 - 2.8e-14 53.2 0.0 1.1e-13 51.4 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 GAN04299.1 - 5.1e-05 23.8 0.1 0.0025 18.4 0.0 3.0 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Dehalogenase PF13486.6 GAN04299.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Reductive dehalogenase subunit HetR_C PF18460.1 GAN04299.1 - 0.12 12.3 0.1 0.54 10.2 0.1 2.2 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain IMPDH PF00478.25 GAN04300.1 - 2.1e-135 451.2 5.7 2.4e-135 451.0 5.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAN04300.1 - 4.6e-11 42.3 1.0 1.2e-10 41.0 0.5 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase CBS PF00571.28 GAN04300.1 - 2.7e-08 34.1 0.4 5.7e-05 23.5 0.0 2.8 2 1 0 2 2 2 2 CBS domain NMO PF03060.15 GAN04300.1 - 8.7e-06 25.3 6.9 0.018 14.4 6.1 2.9 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 GAN04300.1 - 1.1e-05 25.0 1.6 0.0016 18.0 0.2 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.14 GAN04300.1 - 0.00038 19.9 1.0 0.0012 18.2 0.2 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 GAN04300.1 - 0.041 13.3 0.7 0.099 12.0 0.1 1.9 2 0 0 2 2 2 0 KDPG and KHG aldolase PK PF00224.21 GAN04300.1 - 0.047 12.6 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain G3P_antiterm PF04309.12 GAN04300.1 - 0.073 12.5 0.2 7.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Pkinase PF00069.25 GAN04301.1 - 1.7e-50 171.8 0.0 2.4e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04301.1 - 6.2e-34 117.4 0.0 8.4e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN04301.1 - 4.3e-05 22.5 0.0 6.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAN04301.1 - 0.00028 20.3 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1491 PF07372.12 GAN04301.1 - 0.041 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) DDE_2 PF02914.15 GAN04301.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase BAR PF03114.18 GAN04304.1 - 1.4e-28 100.2 2.2 2.4e-28 99.4 2.2 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAN04304.1 - 2.6e-13 49.3 1.9 3.4e-13 49.0 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAN04304.1 - 4.8e-09 35.9 0.1 1.3e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN04304.1 - 1.3e-08 34.4 0.0 2.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_25 PF13649.6 GAN04305.1 - 2.6e-14 53.7 0.1 1e-12 48.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN04305.1 - 3.3e-13 49.8 0.9 2.8e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN04305.1 - 1.9e-12 47.7 0.0 5.9e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN04305.1 - 6.1e-08 32.6 0.0 3.7e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN04305.1 - 1.2e-06 29.2 0.1 6.9e-05 23.5 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain CheR PF01739.18 GAN04305.1 - 6.7e-05 22.5 0.0 0.0002 20.9 0.0 1.8 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 GAN04305.1 - 0.00067 19.1 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN04305.1 - 0.0071 15.8 0.0 0.067 12.6 0.0 2.4 1 1 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 GAN04305.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 GAN04305.1 - 0.041 13.7 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Hypothetical methyltransferase cwf18 PF08315.12 GAN04305.1 - 0.25 12.0 4.0 0.44 11.2 4.0 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor PCI PF01399.27 GAN04306.1 - 2.9e-08 34.2 1.8 1.1e-07 32.3 0.2 2.3 2 0 0 2 2 2 1 PCI domain Spc7 PF08317.11 GAN04306.1 - 0.0024 16.8 0.9 0.0036 16.2 0.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein FliJ PF02050.16 GAN04306.1 - 0.022 15.0 4.2 0.043 14.0 4.2 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein DivIC PF04977.15 GAN04306.1 - 0.049 13.4 1.4 0.049 13.4 1.4 2.0 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 GAN04306.1 - 0.084 12.9 5.5 0.068 13.2 2.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 GAN04306.1 - 0.085 13.5 5.7 1.1 10.0 1.3 2.6 2 0 0 2 2 2 0 SlyX DUF4404 PF14357.6 GAN04306.1 - 0.44 11.2 3.5 0.55 10.9 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Snapin_Pallidin PF14712.6 GAN04306.1 - 4.4 7.8 10.0 0.25 11.8 1.6 2.8 2 1 1 3 3 3 0 Snapin/Pallidin ABC_membrane_2 PF06472.15 GAN04307.1 - 4.7e-91 304.9 0.9 6.2e-91 304.5 0.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAN04307.1 - 1.5e-16 61.1 0.0 4.7e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAN04307.1 - 0.0011 18.4 0.1 0.26 10.7 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAN04307.1 - 0.0036 17.8 1.0 0.0064 17.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAN04307.1 - 0.0036 17.2 0.2 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAN04307.1 - 0.0041 16.8 0.1 0.033 13.9 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAN04307.1 - 0.082 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RhoGAP PF00620.27 GAN04308.1 - 1.1e-39 135.7 3.1 1.3e-39 135.5 0.6 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 GAN04308.1 - 0.0063 16.8 0.1 0.022 15.0 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4795 PF16043.5 GAN04308.1 - 0.051 13.2 5.4 0.1 12.2 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) eIF-5a PF01287.20 GAN04309.1 - 1.6e-30 105.0 0.4 2.2e-30 104.6 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GAN04309.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain MFS_1 PF07690.16 GAN04310.1 - 4.2e-32 111.4 69.6 2e-19 69.7 36.4 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN04310.1 - 4e-10 38.8 32.6 1.8e-07 30.1 11.3 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein RhoGEF PF00621.20 GAN04312.1 - 2.2e-39 135.6 1.2 5.4e-39 134.3 1.2 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 GAN04312.1 - 4.7e-14 52.6 0.0 1.5e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 GAN04312.1 - 2e-07 30.8 0.5 3.6e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN04312.1 - 5.7e-07 29.0 0.6 1.4e-06 27.8 0.6 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN04312.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain TruB_N PF01509.18 GAN04312.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) zf-C2H2 PF00096.26 GAN04313.1 - 6e-06 26.4 9.7 0.0041 17.5 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 GAN04313.1 - 1.9e-05 24.9 4.8 0.063 13.6 0.5 2.7 2 1 0 2 2 2 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 GAN04313.1 - 0.0064 16.9 0.9 0.0064 16.9 0.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain Prok-E2_A PF14457.6 GAN04313.1 - 0.029 14.0 0.0 0.074 12.7 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family A FOXP-CC PF16159.5 GAN04313.1 - 0.067 13.8 5.2 3.2 8.4 0.1 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAN04313.1 - 0.2 12.6 7.7 6.5 7.9 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN04313.1 - 0.37 10.9 0.2 0.37 10.9 0.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger TFR_dimer PF04253.15 GAN04315.1 - 6.1e-23 81.2 0.2 1.2e-22 80.2 0.2 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAN04315.1 - 1.6e-19 70.4 0.0 4.9e-19 68.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAN04315.1 - 2.2e-11 43.6 0.1 5.8e-11 42.3 0.1 1.7 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 GAN04315.1 - 0.0056 16.4 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 YchF-GTPase_C PF06071.13 GAN04316.1 - 5.3e-40 135.5 0.4 1.1e-39 134.5 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAN04316.1 - 2.2e-21 76.1 0.0 6.8e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN04316.1 - 1.4e-07 31.1 0.0 3.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAN04316.1 - 0.057 13.5 0.1 2.7 8.0 0.1 2.5 1 1 1 2 2 2 0 Dynamin family Pkinase PF00069.25 GAN04317.1 - 2.7e-60 204.0 0.0 8.7e-60 202.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04317.1 - 3e-41 141.4 2.0 5.2e-41 140.6 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN04317.1 - 7e-06 25.1 0.0 7e-06 25.1 0.0 3.3 2 1 0 2 2 2 1 Fungal protein kinase DUF4337 PF14235.6 GAN04317.1 - 1.4 9.0 7.8 5.3 7.1 7.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PPP4R2 PF09184.11 GAN04318.1 - 0.71 9.4 21.6 1.1 8.8 21.6 1.3 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GAN04318.1 - 4.6 6.6 27.7 6.2 6.2 27.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAN04318.1 - 9.8 4.2 31.0 12 4.0 31.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S19e PF01090.19 GAN04319.1 - 4.1e-60 201.4 0.1 4.6e-60 201.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 GAN04319.1 - 0.11 12.7 0.3 0.23 11.6 0.1 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain RhoGAP PF00620.27 GAN04320.1 - 3.9e-40 137.2 0.2 6.9e-40 136.4 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain Nod1 PF17114.5 GAN04320.1 - 0.04 14.1 0.2 0.086 13.0 0.2 1.6 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 SprT-like PF10263.9 GAN04320.1 - 0.45 10.4 3.0 0.52 10.2 0.7 2.1 2 0 0 2 2 2 0 SprT-like family DUF3384 PF11864.8 GAN04321.1 - 3.4e-66 224.1 4.7 3.4e-66 224.1 4.7 3.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 GAN04321.1 - 1.1e-50 171.8 0.0 2.9e-50 170.4 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 GAN04321.1 - 4.4e-41 141.2 18.2 3.1e-40 138.4 3.7 4.2 3 1 1 4 4 4 2 Tuberin Mucin PF01456.17 GAN04321.1 - 7 6.6 13.8 0.17 11.9 5.9 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein PCI PF01399.27 GAN04322.1 - 1e-14 54.9 0.4 1e-14 54.9 0.4 2.4 2 1 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 GAN04322.1 - 9.3e-05 22.5 0.1 0.00023 21.3 0.1 1.7 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain RPN7 PF10602.9 GAN04322.1 - 0.0015 18.3 0.3 0.0028 17.4 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF5063 PF16702.5 GAN04322.1 - 0.024 15.0 0.9 0.086 13.2 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) PIN_12 PF16289.5 GAN04322.1 - 0.11 13.0 1.1 0.23 11.9 0.6 1.8 2 0 0 2 2 2 0 PIN domain TORC_N PF12884.7 GAN04322.1 - 0.15 12.9 0.1 0.8 10.5 0.1 2.2 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus PhoD PF09423.10 GAN04323.1 - 1.2e-05 24.5 0.1 0.007 15.4 0.0 2.9 3 0 0 3 3 3 2 PhoD-like phosphatase CAP_N PF01213.19 GAN04323.1 - 0.09 12.3 1.2 0.14 11.6 1.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF240 PF03086.14 GAN04324.1 - 0.008 16.1 3.7 0.023 14.6 3.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF240) Sybindin PF04099.12 GAN04325.1 - 7.6e-23 81.0 0.2 1.6e-22 80.0 0.2 1.5 1 1 0 1 1 1 1 Sybindin-like family RIH_assoc PF08454.11 GAN04326.1 - 1e-21 76.7 6.5 1e-21 76.7 6.5 5.4 6 0 0 6 6 6 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 GAN04326.1 - 5.5e-16 58.4 0.0 2e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 GAN04326.1 - 7.4e-15 55.3 0.0 1.7e-13 50.8 0.0 3.0 1 1 1 2 2 2 1 MIR domain Ion_trans PF00520.31 GAN04326.1 - 3.2e-07 29.8 13.8 6.6e-07 28.8 13.8 1.6 1 0 0 1 1 1 1 Ion transport protein DUF3975 PF13126.6 GAN04326.1 - 1.1 9.7 3.1 6.2 7.3 3.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) Romo1 PF10247.9 GAN04327.1 - 2.4e-24 85.5 12.9 2.9e-24 85.2 12.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Keratin_2_head PF16208.5 GAN04327.1 - 0.034 14.3 3.6 0.042 14.0 3.6 1.1 1 0 0 1 1 1 0 Keratin type II head UCH PF00443.29 GAN04328.1 - 1.7e-32 113.0 1.6 8.6e-32 110.6 1.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 GAN04328.1 - 1.7e-18 66.2 0.5 2.2e-13 49.9 0.1 2.9 2 0 0 2 2 2 2 A repeated domain in UCH-protein PUB PF09409.10 GAN04328.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 PUB domain WW PF00397.26 GAN04329.1 - 3e-12 46.4 1.2 6.1e-12 45.4 1.2 1.6 1 0 0 1 1 1 1 WW domain Aldo_ket_red PF00248.21 GAN04330.1 - 1.1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTCace PF00185.24 GAN04331.1 - 3.1e-49 167.0 0.0 5.9e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 GAN04331.1 - 1.2e-47 161.6 0.1 2.3e-47 160.7 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OCD_Mu_crystall PF02423.15 GAN04331.1 - 0.053 12.5 0.6 0.08 11.9 0.6 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Lustrin_cystein PF14625.6 GAN04331.1 - 0.084 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Aldo_ket_red PF00248.21 GAN04332.1 - 5.9e-45 153.7 0.0 7.5e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.22 GAN04333.1 - 0.026 14.9 0.0 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily HSP70 PF00012.20 GAN04334.1 - 1.1e-81 274.9 21.7 1.1e-81 274.9 21.7 2.9 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GAN04334.1 - 1.6e-05 23.9 4.8 0.00037 19.4 4.8 2.2 1 1 0 1 1 1 1 MreB/Mbl protein V_ATPase_I PF01496.19 GAN04334.1 - 0.53 8.1 15.3 0.58 8.0 9.4 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4637 PF15470.6 GAN04334.1 - 5.8 6.6 15.7 1.1 8.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) WD40 PF00400.32 GAN04335.1 - 9.8e-26 89.5 4.2 2.6e-06 28.0 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04335.1 - 1.5e-15 57.3 1.1 0.00028 21.1 0.0 6.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN04335.1 - 2.2e-08 33.5 3.0 0.0016 17.4 0.2 3.9 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 GAN04335.1 - 1.4e-07 31.0 0.0 3.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 GAN04335.1 - 4.2e-06 25.7 3.4 0.0011 17.8 1.7 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 GAN04335.1 - 0.0045 16.6 0.0 0.023 14.3 0.0 2.0 1 1 1 2 2 2 1 PQQ-like domain PALB2_WD40 PF16756.5 GAN04335.1 - 0.015 14.2 1.9 0.58 9.0 0.1 2.9 1 1 4 5 5 4 0 Partner and localizer of BRCA2 WD40 domain LisH PF08513.11 GAN04335.1 - 0.031 14.3 0.4 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 LisH LRR_5 PF13306.6 GAN04335.1 - 0.84 9.6 5.3 2.2 8.3 0.0 3.1 2 1 2 4 4 4 0 BspA type Leucine rich repeat region (6 copies) Ribosomal_L21p PF00829.21 GAN04336.1 - 2.8e-25 88.5 5.1 3.9e-25 88.0 5.1 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pyridoxal_deC PF00282.19 GAN04337.1 - 1.7e-18 66.5 0.0 2.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAN04337.1 - 1.7e-09 37.1 0.0 3.6e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAN04337.1 - 2.5e-06 27.1 0.1 3.7e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-A20 PF01754.16 GAN04338.1 - 1.3e-10 41.0 7.7 1.3e-10 41.0 7.7 1.9 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 GAN04338.1 - 1e-06 28.8 7.9 1e-06 28.8 7.9 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger Ndc1_Nup PF09531.10 GAN04338.1 - 1.3 7.7 7.3 1.4 7.5 7.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SMN PF06003.12 GAN04339.1 - 0.00016 21.0 5.1 0.00016 21.0 5.1 2.7 2 1 1 3 3 3 1 Survival motor neuron protein (SMN) Pex14_N PF04695.13 GAN04339.1 - 0.004 17.8 5.4 0.004 17.8 5.4 2.0 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HCMV_UL139 PF12507.8 GAN04339.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.5 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein PRIMA1 PF16101.5 GAN04339.1 - 0.091 12.8 0.4 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FYVE PF01363.21 GAN04340.1 - 1.3e-16 60.5 7.8 1.3e-16 60.5 7.8 3.5 3 1 0 3 3 3 1 FYVE zinc finger Rbsn PF11464.8 GAN04340.1 - 2.3e-13 49.6 0.6 4.8e-13 48.6 0.1 1.8 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-C2H2_9 PF16293.5 GAN04340.1 - 0.00064 19.5 0.3 0.00064 19.5 0.3 3.6 4 0 0 4 4 4 1 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 GAN04340.1 - 0.0091 15.8 0.4 0.031 14.1 0.4 1.9 1 0 0 1 1 1 1 GAGA factor FOXP-CC PF16159.5 GAN04340.1 - 0.022 15.4 1.9 4.2 8.1 0.1 3.2 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-Di19 PF05605.12 GAN04340.1 - 0.18 12.1 0.2 0.18 12.1 0.2 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 GAN04340.1 - 0.4 11.0 0.1 0.4 11.0 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon zf-C2H2_4 PF13894.6 GAN04340.1 - 0.52 11.3 0.2 0.52 11.3 0.2 5.7 5 1 1 6 6 6 0 C2H2-type zinc finger zf-met PF12874.7 GAN04340.1 - 0.89 10.0 12.3 0.14 12.6 0.4 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Fasciclin PF02469.22 GAN04342.1 - 2.1e-63 212.3 3.4 1.4e-15 57.7 0.0 5.3 5 0 0 5 5 5 5 Fasciclin domain GTP_EFTU PF00009.27 GAN04342.1 - 8.4e-21 74.4 0.6 1.7e-20 73.4 0.6 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HARP PF07443.13 GAN04342.1 - 0.055 13.1 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 HepA-related protein (HARP) PH PF00169.29 GAN04343.1 - 1.2e-07 32.2 1.5 2.8e-07 31.0 1.5 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAN04343.1 - 1.1e-05 25.8 6.3 6.1e-05 23.4 1.5 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 GAN04343.1 - 0.0076 16.6 1.0 0.027 14.8 1.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain DUF2963 PF11178.8 GAN04344.1 - 0.2 11.4 0.0 0.46 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2963) Ion_trans PF00520.31 GAN04345.1 - 3.4e-05 23.2 4.6 4.4e-05 22.8 4.6 1.1 1 0 0 1 1 1 1 Ion transport protein LSDAT_euk PF18139.1 GAN04345.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM Radial_spoke_3 PF06098.11 GAN04345.1 - 0.093 12.0 3.5 0.13 11.6 3.5 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Sina PF03145.16 GAN04346.1 - 4.4e-06 26.8 23.6 0.00071 19.6 5.8 3.4 2 1 1 3 3 3 2 Seven in absentia protein family zf-RING_6 PF14835.6 GAN04346.1 - 5.6e-05 22.9 4.4 0.00018 21.3 4.4 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 GAN04346.1 - 7.8e-05 22.4 16.0 7.8e-05 22.4 16.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN04346.1 - 0.00037 20.3 11.6 0.0014 18.5 11.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAN04346.1 - 0.0014 18.7 14.5 0.0014 18.7 14.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAN04346.1 - 0.0074 16.6 14.9 0.0074 16.6 14.9 2.6 2 1 0 2 2 2 1 Ring finger domain U-box PF04564.15 GAN04346.1 - 0.021 15.0 0.5 0.41 10.9 0.3 3.0 2 0 0 2 2 2 0 U-box domain zf-RING_UBOX PF13445.6 GAN04346.1 - 4.7 7.3 18.3 0.049 13.7 7.9 3.0 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAN04346.1 - 7.9 6.5 21.5 0.12 12.4 13.6 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Dcc1 PF09724.9 GAN04348.1 - 3e-80 270.1 0.3 3.7e-80 269.7 0.3 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 EF-hand_1 PF00036.32 GAN04349.1 - 0.0036 16.7 0.3 0.014 14.9 0.3 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAN04349.1 - 0.013 15.3 2.1 0.027 14.4 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 GAN04349.1 - 0.077 13.5 1.2 0.64 10.5 0.0 3.0 4 0 0 4 4 4 0 EF-hand domain pair RabGAP-TBC PF00566.18 GAN04350.1 - 2.8e-45 154.6 0.7 7.1e-45 153.3 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 GAN04350.1 - 6.3e-29 100.2 0.9 8.4e-16 57.9 0.5 2.4 2 0 0 2 2 2 2 GRAM domain R3H PF01424.22 GAN04351.1 - 9.1e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 GAN04351.1 - 0.0002 21.1 0.0 0.00049 19.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cut12 PF11500.8 GAN04351.1 - 1.4 8.9 3.8 1.2 9.1 1.9 1.9 2 0 0 2 2 2 0 Spindle pole body formation-associated protein EF-hand_4 PF12763.7 GAN04352.1 - 1.2e-42 144.1 0.0 5.6e-17 61.6 0.0 3.8 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 GAN04352.1 - 5.6e-08 33.1 0.0 0.0022 18.4 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAN04352.1 - 6.5e-06 25.3 4.2 0.76 9.5 0.0 5.2 6 0 0 6 6 6 2 EF hand UBA PF00627.31 GAN04352.1 - 0.00019 21.2 0.1 0.00043 20.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 GAN04352.1 - 0.00093 18.9 1.6 18 5.6 0.0 5.5 5 0 0 5 5 5 0 EF-hand domain EF-hand_8 PF13833.6 GAN04352.1 - 0.0037 17.1 1.9 3.8 7.4 0.0 4.7 5 1 1 6 6 5 1 EF-hand domain pair TPR_MLP1_2 PF07926.12 GAN04352.1 - 0.0037 17.3 20.6 0.0037 17.3 20.6 3.2 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 GAN04352.1 - 0.015 14.2 31.0 0.15 10.9 30.7 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 GAN04352.1 - 0.037 14.6 35.3 0.057 13.9 12.8 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF745 PF05335.13 GAN04352.1 - 0.057 13.1 24.5 0.033 13.9 20.4 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF4201 PF13870.6 GAN04352.1 - 0.13 12.0 26.7 0.059 13.1 13.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 GAN04352.1 - 0.67 10.2 27.9 0.021 15.1 10.8 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Sec8_exocyst PF04048.14 GAN04352.1 - 0.8 9.6 15.5 2.4 8.0 3.2 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PRKG1_interact PF15898.5 GAN04352.1 - 1.2 10.1 27.9 0.29 12.0 10.7 3.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Seryl_tRNA_N PF02403.22 GAN04352.1 - 1.4 9.2 24.7 0.045 14.0 10.4 3.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.10 GAN04352.1 - 1.8 8.9 30.5 0.59 10.5 8.4 3.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) HAUS-augmin3 PF14932.6 GAN04352.1 - 2.4 7.7 28.2 2.3 7.7 17.4 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BRE1 PF08647.11 GAN04352.1 - 3 8.0 29.9 1.7 8.8 13.1 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 GAN04352.1 - 4.6 6.5 32.7 11 5.3 30.6 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding kleA_kleC PF17383.2 GAN04352.1 - 5.3 7.4 11.4 4.5 7.7 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A CENP-F_leu_zip PF10473.9 GAN04352.1 - 7.3 6.6 30.5 5 7.2 17.0 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 GAN04352.1 - 8.6 6.4 19.5 7.6 6.6 4.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAN04352.1 - 9.3 4.6 10.9 19 3.6 10.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DJ-1_PfpI PF01965.24 GAN04353.1 - 4.6e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAN04353.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 2 0 0 2 2 2 0 ThiJ/PfpI family-like RGS PF00615.19 GAN04354.1 - 3.9e-21 75.5 0.6 3.9e-21 75.5 0.6 2.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 GAN04354.1 - 6.3e-05 22.9 1.8 0.11 12.6 0.0 3.4 3 1 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PPR_2 PF13041.6 GAN04356.1 - 3.7e-66 219.1 15.1 9.9e-12 44.9 0.1 15.7 10 4 7 17 17 16 14 PPR repeat family PPR PF01535.20 GAN04356.1 - 7.6e-44 144.9 25.9 5.2e-05 23.2 0.1 17.6 21 0 0 21 21 19 10 PPR repeat PPR_1 PF12854.7 GAN04356.1 - 2.3e-34 116.8 0.0 2.3e-06 27.2 0.0 11.7 13 0 0 13 13 13 7 PPR repeat PPR_3 PF13812.6 GAN04356.1 - 1.5e-33 114.6 11.2 1.7e-10 40.8 0.1 10.9 10 2 3 13 13 13 8 Pentatricopeptide repeat domain PPR_long PF17177.4 GAN04356.1 - 3.1e-30 105.1 19.8 9.5e-10 38.2 0.2 6.9 3 2 4 7 7 7 5 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GAN04356.1 - 5.5e-07 30.0 15.3 0.037 14.5 0.1 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat RPM2 PF08579.11 GAN04356.1 - 1.3e-06 28.8 0.5 0.019 15.4 0.0 4.9 4 1 0 4 4 4 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_MalT PF17874.1 GAN04356.1 - 7.4e-05 22.3 3.5 0.049 13.0 0.0 3.9 4 1 0 4 4 4 2 MalT-like TPR region ATP13 PF12921.7 GAN04356.1 - 0.014 15.3 4.0 6.1 6.7 0.0 6.2 7 2 3 10 10 10 0 Mitochondrial ATPase expression TPR_7 PF13176.6 GAN04356.1 - 0.032 14.2 8.7 28 5.1 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF5344 PF17279.2 GAN04356.1 - 0.04 14.5 1.2 0.55 10.8 0.0 3.5 2 0 0 2 2 2 0 Family of unknown function (DUF5344) TPR_12 PF13424.6 GAN04356.1 - 0.072 13.4 15.1 7.3 7.0 0.1 6.8 8 1 0 8 8 8 0 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 GAN04356.1 - 0.19 11.8 1.3 1.5 8.9 0.2 2.8 3 0 0 3 3 2 0 Spinocerebellar ataxia type 10 protein domain IES5 PF17335.2 GAN04356.1 - 0.26 11.6 2.4 0.98 9.7 0.1 2.9 2 0 0 2 2 2 0 Ino80 complex subunit 5 TPR_8 PF13181.6 GAN04356.1 - 8.6 6.9 17.5 57 4.3 0.5 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.15 GAN04358.1 - 8.3e-06 26.0 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Not3 PF04065.15 GAN04358.1 - 0.016 14.6 1.2 0.022 14.2 1.2 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Glyoxalase_2 PF12681.7 GAN04358.1 - 0.043 13.7 0.4 0.057 13.3 0.4 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain IP_trans PF02121.18 GAN04359.1 - 4.9e-107 357.1 1.4 5.5e-107 356.9 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein zf-HIT PF04438.16 GAN04360.1 - 3.5e-09 36.4 6.6 5.5e-09 35.7 6.6 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYST PF17772.1 GAN04360.1 - 1.1 8.9 6.7 0.29 10.8 3.1 1.8 2 0 0 2 2 2 0 MYST family zinc finger domain Cellulase PF00150.18 GAN04361.1 - 4.5e-07 29.6 9.4 6.3e-06 25.8 9.4 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RhoGAP PF00620.27 GAN04362.1 - 2.7e-43 147.4 0.0 6.2e-43 146.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 GAN04362.1 - 5.3e-12 45.8 0.0 1.5e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain ATP-synt_E PF05680.12 GAN04363.1 - 3.5e-20 72.1 1.0 4e-20 72.0 1.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain COA2 PF17051.5 GAN04364.1 - 1.1e-08 35.0 0.6 1.5e-08 34.5 0.6 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 DUF4648 PF15505.6 GAN04366.1 - 0.075 13.9 0.2 0.22 12.4 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4648) G-alpha PF00503.20 GAN04367.1 - 9.3e-119 396.7 8.3 1.1e-118 396.5 8.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN04367.1 - 3e-16 59.4 3.6 7.4e-12 45.1 0.4 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN04367.1 - 0.00027 20.4 6.3 0.0043 16.4 0.2 3.0 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN04367.1 - 0.0052 16.8 0.1 3 8.0 0.0 2.6 1 1 1 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 GAN04367.1 - 0.0069 16.6 0.3 2.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAN04367.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.20 GAN04367.1 - 0.029 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.18 GAN04367.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 GAN04367.1 - 0.062 12.4 0.2 0.2 10.7 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain MRP-L47 PF06984.13 GAN04368.1 - 2.8e-28 97.9 3.2 4.1e-28 97.3 3.2 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 GAN04368.1 - 3.4e-07 30.1 2.0 7.6e-07 29.0 2.0 1.6 1 0 0 1 1 1 1 Ribosomal L29 protein DUF3328 PF11807.8 GAN04368.1 - 0.034 13.9 0.6 0.04 13.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Glyco_hydro_63 PF03200.16 GAN04369.1 - 4.6e-172 573.2 4.6 1.3e-170 568.4 4.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 GAN04369.1 - 5.8e-68 229.4 0.0 1.1e-67 228.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 GAN04369.1 - 0.0076 15.1 0.2 0.015 14.2 0.1 1.5 2 0 0 2 2 2 1 Trehalase HTH_23 PF13384.6 GAN04370.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 GAN04370.1 - 0.00017 21.6 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 GAN04370.1 - 0.00039 21.0 0.0 0.00092 19.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 GAN04370.1 - 0.0006 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_3 PF01381.22 GAN04370.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_17 PF12728.7 GAN04370.1 - 0.021 15.0 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 GAN04370.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix CTC1 PF15489.6 GAN04372.1 - 1.6e-17 62.4 0.0 6.6e-14 50.5 0.0 2.2 2 0 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 USP7_ICP0_bdg PF12436.8 GAN04373.1 - 6.7e-63 212.2 0.3 5.2e-62 209.3 0.0 2.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 GAN04373.1 - 5.6e-50 169.9 1.4 5.6e-50 169.9 1.4 4.5 5 0 0 5 5 5 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 GAN04373.1 - 1.7e-48 165.4 0.2 1.7e-48 165.4 0.2 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mcp5_PH PF12814.7 GAN04373.1 - 2e-28 99.0 0.2 2e-28 99.0 0.2 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology UCH_1 PF13423.6 GAN04373.1 - 1.5e-24 87.2 0.0 1.5e-24 87.2 0.0 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.8 GAN04373.1 - 0.00085 19.8 1.3 6.5 7.3 0.1 4.3 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 CENP-F_leu_zip PF10473.9 GAN04373.1 - 0.29 11.1 34.2 0.13 12.3 1.6 4.5 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_TACC PF12709.7 GAN04373.1 - 6 7.4 28.1 4.1 7.9 3.4 5.1 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins UQ_con PF00179.26 GAN04374.1 - 3.3e-39 133.8 0.0 4.5e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4160 PF13711.6 GAN04374.1 - 0.096 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) EMP24_GP25L PF01105.24 GAN04375.1 - 3.6e-46 157.4 0.3 4.4e-46 157.1 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 GAN04375.1 - 0.016 13.4 0.8 0.02 13.1 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ZapB PF06005.12 GAN04375.1 - 0.043 14.3 0.7 0.089 13.3 0.7 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Aminotran_5 PF00266.19 GAN04376.1 - 4.1e-22 78.7 0.0 5.2e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAN04376.1 - 0.00035 19.9 0.0 0.00059 19.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Spindle_Spc25 PF08234.12 GAN04378.1 - 1.3e-15 57.4 0.7 3.5e-15 56.0 0.7 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Mod_r PF07200.13 GAN04378.1 - 0.0043 17.2 16.4 0.0043 17.2 16.4 2.6 2 1 1 3 3 3 1 Modifier of rudimentary (Mod(r)) protein SEP PF08059.13 GAN04378.1 - 0.0091 16.6 2.3 0.031 14.9 2.3 1.9 1 0 0 1 1 1 1 SEP domain DDA1 PF10172.9 GAN04378.1 - 0.077 13.3 1.9 0.17 12.2 0.9 2.1 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase mCpol PF18182.1 GAN04378.1 - 1.6 9.1 5.1 3.2 8.1 0.0 2.9 2 1 2 4 4 4 0 minimal CRISPR polymerase domain Ribosomal_L18 PF17135.4 GAN04379.1 - 1.5e-88 295.1 5.1 1.7e-88 294.9 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAN04379.1 - 0.0015 19.2 0.2 0.004 17.8 0.2 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NAP PF00956.18 GAN04380.1 - 4.4e-15 55.6 15.0 1.5e-11 44.0 3.2 3.9 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Na_trans_assoc PF06512.13 GAN04380.1 - 0.0023 18.2 3.1 0.0046 17.3 3.1 1.6 1 1 0 1 1 1 1 Sodium ion transport-associated L27_1 PF09058.10 GAN04380.1 - 0.063 13.3 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 L27_1 Nop14 PF04147.12 GAN04380.1 - 0.7 8.0 12.9 0.9 7.7 12.9 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAN04380.1 - 1 8.7 14.0 1.3 8.3 14.0 1.1 1 0 0 1 1 1 0 BUD22 TPR_1 PF00515.28 GAN04381.1 - 3.1e-46 153.4 18.2 1.6e-07 30.8 0.1 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAN04381.1 - 3.8e-45 148.4 14.9 0.00016 21.6 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.6 GAN04381.1 - 1.7e-32 110.8 13.2 5.8e-08 32.3 0.1 8.5 6 3 3 9 9 8 5 TPR repeat TPR_16 PF13432.6 GAN04381.1 - 2.8e-28 98.3 2.4 3.9e-05 24.2 0.0 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAN04381.1 - 1.8e-27 93.7 4.3 0.0033 17.7 0.1 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAN04381.1 - 4.3e-27 92.0 15.1 0.0081 16.3 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAN04381.1 - 2.1e-26 92.2 13.0 1.6e-06 28.5 0.0 6.7 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAN04381.1 - 1.2e-25 88.0 11.9 0.0015 19.2 0.1 10.2 2 2 9 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAN04381.1 - 2.7e-22 78.9 19.6 2.8e-05 24.3 0.1 8.0 3 3 5 8 8 8 7 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN04381.1 - 9.1e-13 48.2 15.3 0.0058 16.8 1.8 6.0 2 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAN04381.1 - 1.8e-12 46.3 6.9 0.21 11.7 0.0 8.9 10 0 0 10 10 9 2 Tetratricopeptide repeat NARP1 PF12569.8 GAN04381.1 - 2.2e-12 46.7 0.7 0.00027 20.0 0.0 3.7 3 1 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 GAN04381.1 - 2.2e-11 43.8 7.6 0.035 14.2 0.3 6.2 2 1 5 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAN04381.1 - 5e-08 32.6 11.4 0.22 11.4 0.1 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN04381.1 - 5e-08 32.5 3.7 0.034 13.4 0.0 4.7 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN04381.1 - 9.9e-08 32.2 18.9 3.3 8.6 0.0 9.4 11 0 0 11 11 10 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAN04381.1 - 6.7e-07 29.4 4.5 0.0074 16.2 1.2 3.6 3 1 2 5 5 5 2 Virulence factor membrane-bound polymerase, C-terminal TPR_MalT PF17874.1 GAN04381.1 - 1.4e-06 27.9 13.7 0.061 12.7 0.0 5.1 4 2 0 4 4 4 2 MalT-like TPR region BTAD PF03704.17 GAN04381.1 - 2.8e-06 27.8 4.9 0.19 12.1 0.3 5.3 3 2 2 5 5 5 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 GAN04381.1 - 4.8e-06 26.7 0.0 80 4.3 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAN04381.1 - 5.2e-06 26.1 0.7 0.0068 15.9 0.0 2.8 2 1 0 2 2 2 2 Coatomer epsilon subunit TPR_3 PF07720.12 GAN04381.1 - 0.0015 18.5 10.3 4.2 7.5 1.3 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat MIT PF04212.18 GAN04381.1 - 0.0043 17.1 15.0 0.12 12.4 0.1 6.8 7 1 2 9 9 8 1 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 GAN04381.1 - 0.0055 15.8 0.2 1.2 8.1 0.1 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_5 PF12688.7 GAN04381.1 - 0.016 15.4 0.2 0.58 10.4 0.0 3.4 4 0 0 4 4 3 0 Tetratrico peptide repeat TPR_20 PF14561.6 GAN04381.1 - 0.045 14.1 6.2 4.8 7.6 0.0 5.2 5 1 2 7 7 5 0 Tetratricopeptide repeat PG_binding_4 PF12229.8 GAN04381.1 - 0.056 13.7 0.0 1.6 9.1 0.0 2.8 2 1 1 3 3 2 0 Putative peptidoglycan binding domain Clathrin PF00637.20 GAN04381.1 - 0.092 12.6 2.2 0.54 10.1 0.0 3.4 3 2 0 3 3 3 0 Region in Clathrin and VPS TAF1_subA PF14929.6 GAN04381.1 - 0.13 11.6 0.6 1.1 8.5 0.4 2.3 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A Mad3_BUB1_I PF08311.12 GAN04381.1 - 0.22 11.5 3.4 36 4.4 0.2 3.9 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 DUF3947 PF13135.6 GAN04381.1 - 0.23 11.7 1.5 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) DUF5113 PF17140.4 GAN04381.1 - 1.3 8.8 9.8 14 5.5 0.0 4.7 4 3 1 6 6 6 0 Domain of unknown function (DUF5113) YfdX PF10938.8 GAN04381.1 - 7.6 6.5 11.9 15 5.5 0.1 5.2 5 1 1 6 6 6 0 YfdX protein Vps55 PF04133.14 GAN04382.1 - 1.3e-45 154.1 8.8 1.6e-45 153.8 8.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Ank_2 PF12796.7 GAN04383.1 - 0.049 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3439 PF11921.8 GAN04383.1 - 0.086 12.8 0.7 0.27 11.2 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PAP_central PF04928.17 GAN04384.1 - 3.1e-109 363.7 0.0 4.2e-109 363.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAN04384.1 - 9.9e-40 135.9 0.0 2e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAN04384.1 - 2.4e-09 37.4 0.0 6.3e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 GAN04384.1 - 0.027 14.3 0.2 0.048 13.4 0.2 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Glyco_transf_15 PF01793.16 GAN04385.1 - 7.1e-102 341.0 16.0 1.6e-55 188.6 11.5 3.1 2 1 1 3 3 3 3 Glycolipid 2-alpha-mannosyltransferase DUF3097 PF11296.8 GAN04385.1 - 0.0054 16.0 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3097) SUR7 PF06687.12 GAN04385.1 - 0.02 14.6 1.3 0.024 14.2 0.1 1.6 2 0 0 2 2 2 0 SUR7/PalI family BAF250_C PF12031.8 GAN04386.1 - 0.0073 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa zf-C2H2 PF00096.26 GAN04386.1 - 0.034 14.6 9.7 1.4 9.5 0.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAN04386.1 - 0.047 14.3 9.4 0.7 10.6 1.5 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain F-box-like PF12937.7 GAN04387.1 - 7.9e-09 35.3 2.3 7.9e-09 35.3 2.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN04387.1 - 3.4e-08 33.2 0.6 1.5e-07 31.1 0.6 2.2 1 0 0 1 1 1 1 F-box domain TPR_19 PF14559.6 GAN04387.1 - 4.1e-05 24.0 0.3 0.017 15.6 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN04387.1 - 0.00074 19.7 8.1 0.049 13.8 6.0 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAN04387.1 - 0.0021 18.7 0.8 0.025 15.2 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat LRR_4 PF12799.7 GAN04387.1 - 0.0053 17.1 22.8 0.074 13.5 0.4 6.1 4 1 3 7 7 7 3 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 GAN04387.1 - 0.0056 16.5 1.8 0.028 14.3 0.0 3.0 4 0 0 4 4 4 1 F-box TPR_8 PF13181.6 GAN04387.1 - 0.1 12.8 0.1 1.4 9.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 GAN04387.1 - 1.6 9.0 16.7 5 7.4 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 GAN04387.1 - 2.4 8.0 13.5 1.2 8.9 0.5 4.3 2 1 2 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 GAN04388.1 - 0.024 14.5 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like Prenyltrans PF00432.21 GAN04389.1 - 3.1e-26 90.8 6.4 1.9e-08 33.9 0.0 6.5 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat DNA_mis_repair PF01119.19 GAN04390.1 - 1.9e-25 88.8 0.0 5.1e-25 87.5 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAN04390.1 - 7.6e-12 45.2 0.6 4.3e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 GAN04390.1 - 1.9e-09 37.4 0.0 4.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 GAN04390.1 - 0.00012 22.6 0.0 0.00033 21.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SDA1 PF05285.12 GAN04390.1 - 0.14 11.6 1.4 0.24 10.8 1.4 1.3 1 0 0 1 1 1 0 SDA1 Fe_dep_repr_C PF02742.15 GAN04390.1 - 0.14 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Glycos_transf_2 PF00535.26 GAN04391.1 - 3.3e-20 72.6 0.0 5.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAN04391.1 - 5.8e-07 29.6 0.0 8.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAN04391.1 - 0.0052 16.3 0.1 0.42 10.0 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 POP1 PF06978.11 GAN04392.1 - 6.9e-42 143.8 15.0 9.8e-23 81.2 7.5 2.6 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 GAN04392.1 - 7.6e-29 99.9 2.2 2.9e-28 98.0 0.0 2.8 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 GAN04392.1 - 2e-05 24.1 0.0 0.052 12.9 0.0 2.8 2 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain DUF3161 PF11362.8 GAN04392.1 - 0.029 14.3 0.0 0.69 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) Zn_clus PF00172.18 GAN04393.1 - 0.0024 18.0 13.0 0.0052 16.9 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 GAN04394.1 - 0.00014 22.0 10.5 0.00031 20.8 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin_1 PF12718.7 GAN04394.1 - 0.0066 16.6 3.7 0.012 15.8 3.7 1.3 1 0 0 1 1 1 1 Tropomyosin like Jnk-SapK_ap_N PF09744.9 GAN04394.1 - 0.17 12.1 2.7 0.37 11.0 2.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ABC1 PF03109.16 GAN04395.1 - 4.8e-31 107.4 0.0 8.5e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 GAN04395.1 - 3.5e-05 23.5 1.4 6.3e-05 22.7 0.0 2.1 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.25 GAN04395.1 - 0.0091 15.4 0.0 0.023 14.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAN04395.1 - 0.013 15.5 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Yip1 PF04893.17 GAN04396.1 - 9.7e-20 71.0 6.8 1.3e-19 70.5 6.8 1.1 1 0 0 1 1 1 1 Yip1 domain DUF5600 PF18150.1 GAN04397.1 - 1.8e-40 137.9 2.6 3.9e-40 136.7 2.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 GAN04397.1 - 1.8e-22 79.2 0.1 2e-21 75.9 0.0 2.7 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 GAN04397.1 - 4.9e-14 51.9 0.0 9.3e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 GAN04397.1 - 2e-13 50.8 0.0 1.8e-12 47.6 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAN04397.1 - 2.1e-07 31.0 0.0 5.2e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 GAN04397.1 - 2.7e-06 26.5 0.4 1.1e-05 24.6 0.2 2.3 2 0 0 2 2 1 1 EF hand GTP_EFTU PF00009.27 GAN04397.1 - 2.4e-05 23.9 0.0 5.7e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN04397.1 - 5e-05 22.8 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_6 PF13405.6 GAN04397.1 - 0.00037 20.2 0.1 0.0034 17.2 0.1 2.7 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.6 GAN04397.1 - 0.00057 20.3 0.1 0.0046 17.4 0.0 2.6 1 1 0 1 1 1 1 EF-hand domain pair Roc PF08477.13 GAN04397.1 - 0.00084 19.5 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.6 GAN04397.1 - 0.0052 16.6 0.1 0.052 13.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair FeoB_N PF02421.18 GAN04397.1 - 0.016 14.7 0.0 0.47 10.0 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B UvrD_C PF13361.6 GAN04397.1 - 0.027 13.9 1.0 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SRPRB PF09439.10 GAN04397.1 - 0.05 13.0 0.1 1.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 GAN04397.1 - 0.1 12.6 0.0 0.61 10.1 0.0 2.2 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAN04397.1 - 0.16 12.4 0.2 0.69 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 GAN04397.1 - 0.18 12.0 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 GAN04398.1 - 1.1e-44 152.3 0.5 1.4e-44 151.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN04398.1 - 1.2e-37 129.8 0.1 1.6e-37 129.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN04398.1 - 0.00028 20.9 0.9 0.00051 20.0 0.9 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAN04398.1 - 0.03 13.6 0.1 0.053 12.8 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GAN04398.1 - 0.074 12.5 0.5 0.12 11.8 0.4 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF5427 PF10310.9 GAN04399.1 - 8.4e-48 163.5 19.3 5.9e-45 154.1 11.4 2.6 1 1 1 2 2 2 2 Family of unknown function (DUF5427) DUF2076 PF09849.9 GAN04399.1 - 0.011 15.8 8.6 0.02 14.9 8.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) GCP_N_terminal PF17681.1 GAN04400.1 - 1e-43 150.1 1.1 1.8e-43 149.3 0.3 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAN04400.1 - 2e-32 112.9 8.3 3.5e-32 112.1 8.3 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal ANTH PF07651.16 GAN04401.1 - 1.9e-49 168.2 2.5 2.7e-49 167.6 2.5 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 GAN04401.1 - 1.8e-09 37.7 0.1 3.8e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 ENTH domain PEPCK_N PF17297.2 GAN04401.1 - 0.057 13.0 0.2 0.23 11.0 0.1 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase N-terminal domain DUF5061 PF16587.5 GAN04401.1 - 1.1 9.4 6.0 0.84 9.7 0.8 3.2 3 0 0 3 3 3 0 17 kDa common-antigen outer membrane protein Barwin PF00967.17 GAN04402.1 - 2.3e-06 27.5 0.7 7.8e-06 25.7 0.4 1.9 1 1 1 2 2 2 1 Barwin family DPBB_1 PF03330.18 GAN04402.1 - 1.2e-05 25.5 0.3 2.9e-05 24.3 0.2 1.9 2 1 0 2 2 2 1 Lytic transglycolase DUF871 PF05913.11 GAN04402.1 - 0.0026 17.0 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF871) YWFCY PF14293.6 GAN04402.1 - 0.073 13.4 0.1 12 6.2 0.0 2.4 2 0 0 2 2 2 0 YWFCY protein DUF3605 PF12239.8 GAN04403.1 - 6.5e-27 94.7 4.0 2.7e-25 89.5 4.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) AntA PF08346.12 GAN04403.1 - 0.083 13.5 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 AntA/AntB antirepressor zf-RING_UBOX PF13445.6 GAN04404.1 - 1.2e-07 31.6 5.6 1.2e-07 31.6 5.6 4.8 5 1 0 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAN04404.1 - 2.7e-07 30.3 9.7 2.7e-07 30.3 9.7 5.7 5 2 1 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN04404.1 - 1.3e-06 28.6 10.7 1.3e-06 28.6 10.7 5.9 5 2 0 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.6 GAN04404.1 - 3.9e-05 23.4 10.2 3.9e-05 23.4 10.2 5.7 5 2 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAN04404.1 - 5.2e-05 23.3 10.0 5.2e-05 23.3 10.0 6.2 7 1 0 7 7 7 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GAN04404.1 - 8.3e-05 22.5 8.9 8.3e-05 22.5 8.9 5.6 5 2 0 5 5 5 1 zinc-RING finger domain IBR PF01485.21 GAN04404.1 - 0.00017 21.8 9.1 0.00017 21.8 9.1 6.2 5 3 2 7 7 7 2 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 GAN04404.1 - 0.016 15.1 10.9 0.016 15.1 10.9 5.5 5 2 1 6 6 6 0 Prokaryotic RING finger family 4 bZIP_2 PF07716.15 GAN04405.1 - 8.1e-05 22.6 11.4 8.1e-05 22.6 11.4 3.3 3 1 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN04405.1 - 0.02 15.0 16.8 0.087 12.9 6.7 3.0 2 1 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 GAN04405.1 - 0.19 12.2 13.8 1.4 9.5 0.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 GAN04405.1 - 2.4 8.8 6.4 1 10.1 0.2 2.9 3 0 0 3 3 3 0 Initiation control protein YabA FliD_N PF02465.18 GAN04405.1 - 9.8 6.9 19.2 2.3 9.0 0.6 4.1 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus RRM_1 PF00076.22 GAN04406.1 - 2e-23 82.0 0.0 1.5e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 GAN04406.1 - 2.5e-21 74.1 0.0 1.7e-05 24.2 0.0 6.5 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 GAN04406.1 - 0.0017 18.2 0.0 0.92 9.4 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4578 PF15147.6 GAN04406.1 - 1.3 9.9 13.6 0.069 14.0 6.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) TFIIA PF03153.13 GAN04406.1 - 2.2 8.2 33.5 0.39 10.7 18.0 3.0 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit YchF-GTPase_C PF06071.13 GAN04407.1 - 3.9e-38 129.5 1.5 6.7e-38 128.7 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAN04407.1 - 9.9e-24 83.6 0.0 3.4e-23 81.9 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN04407.1 - 3.8e-08 33.0 0.0 6.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAN04407.1 - 0.0011 19.0 0.1 1.5 8.9 0.1 2.9 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 GAN04407.1 - 0.0083 15.1 0.1 0.033 13.2 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 GAN04407.1 - 0.039 13.7 0.0 1.2 8.9 0.0 2.2 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TGS PF02824.21 GAN04407.1 - 0.087 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 TGS domain AMP-binding PF00501.28 GAN04408.1 - 2.3e-33 115.4 0.0 2.1e-32 112.2 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme PseudoU_synth_1 PF01416.20 GAN04410.1 - 7.9e-09 36.0 0.0 2.5e-06 27.9 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF2344 PF10105.9 GAN04410.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF2895 PF11444.8 GAN04410.1 - 0.1 12.0 1.0 8.3 5.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) AA_kinase PF00696.28 GAN04411.1 - 3.7e-37 128.2 0.9 8.5e-37 127.0 0.1 1.8 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 GAN04411.1 - 2.7e-14 52.7 2.2 4.3e-10 39.2 0.4 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 GAN04411.1 - 7.3e-13 48.1 0.8 4.6e-05 23.1 0.1 3.0 2 0 0 2 2 2 2 ACT domain SecD-TM1 PF13721.6 GAN04411.1 - 0.2 12.2 1.1 8.3 6.9 0.1 3.2 3 1 1 4 4 4 0 SecD export protein N-terminal TM region Histone PF00125.24 GAN04412.1 - 7.6e-52 175.1 2.8 8.4e-52 175.0 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAN04412.1 - 1.4e-05 25.4 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAN04412.1 - 7.4e-05 22.8 0.4 0.00013 22.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 GAN04412.1 - 0.00015 22.3 1.6 0.00019 22.0 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 GAN04412.1 - 0.0015 18.8 0.1 0.0028 17.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAN04412.1 - 0.016 15.3 0.2 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN04412.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SWIRM-assoc_1 PF16495.5 GAN04413.1 - 0.63 10.0 6.4 0.8 9.7 0.5 2.3 2 0 0 2 2 2 0 SWIRM-associated region 1 ELP6 PF09807.9 GAN04414.1 - 2.1e-52 178.0 1.7 2.4e-52 177.8 1.7 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 GAN04414.1 - 1.2e-08 34.8 0.7 1.9e-08 34.2 0.7 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 ATPase PF06745.13 GAN04414.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 KaiC DUF835 PF05763.12 GAN04414.1 - 0.015 15.0 2.1 0.027 14.2 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF835) AAA_25 PF13481.6 GAN04414.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_S41 PF03572.18 GAN04415.1 - 3.6e-08 33.1 0.0 8.9e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Peptidase_M19 PF01244.21 GAN04416.1 - 4.7e-113 377.6 0.0 5.4e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RRM_1 PF00076.22 GAN04417.1 - 7.9e-35 118.5 0.2 1.5e-16 60.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN04417.1 - 1.6e-11 44.2 3.1 4.4e-05 23.5 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GAN04417.1 - 0.013 15.5 0.0 0.54 10.3 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAN04417.1 - 0.029 14.4 0.0 7 6.8 0.0 2.9 2 0 0 2 2 2 0 RNA binding motif Tubulin PF00091.25 GAN04418.1 - 1.1e-69 234.6 0.0 1.8e-69 233.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAN04418.1 - 8.8e-41 139.0 0.0 1.4e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAN04418.1 - 5.1e-06 26.8 0.7 8.7e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GAN04418.1 - 0.061 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin like DUF2870 PF11069.8 GAN04418.1 - 1.6 9.2 3.5 2.9 8.4 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) HMG_box PF00505.19 GAN04419.1 - 3.3e-32 110.7 7.3 4.6e-16 59.0 0.2 4.1 4 0 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN04419.1 - 1.4e-23 83.3 9.5 4.9e-13 49.5 0.1 4.0 4 0 0 4 4 4 3 HMG-box domain CHDNT PF08073.12 GAN04419.1 - 0.0027 17.6 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 1 CHDNT (NUC034) domain HMG_box_5 PF14887.6 GAN04419.1 - 0.048 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Pkinase PF00069.25 GAN04420.1 - 3.1e-17 62.8 0.0 4.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAN04420.1 - 3.2e-10 39.4 0.1 3.2e-10 39.4 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase Metallophos PF00149.28 GAN04420.1 - 2.3e-09 38.0 0.1 5.9e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase_Tyr PF07714.17 GAN04420.1 - 2e-05 24.0 0.0 3.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 GAN04420.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1980 PF09323.10 GAN04420.1 - 4.7 7.1 5.0 2 8.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Peptidase_M20 PF01546.28 GAN04421.1 - 4.7e-32 111.4 0.0 5.9e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAN04421.1 - 2.6e-12 46.6 0.0 5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WG_beta_rep PF14903.6 GAN04421.1 - 0.15 12.4 0.2 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 WG containing repeat p450 PF00067.22 GAN04422.1 - 2.1e-74 250.9 0.0 3.2e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mpv17_PMP22 PF04117.12 GAN04423.1 - 2.1e-08 34.3 1.0 4.2e-08 33.3 1.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Methyltransf_34 PF11312.8 GAN04424.1 - 7.9e-56 189.5 2.3 1.9e-55 188.3 2.3 1.6 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase CheR PF01739.18 GAN04424.1 - 8.8e-05 22.1 2.1 0.26 10.8 0.6 3.2 2 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain RE_LlaMI PF09562.10 GAN04424.1 - 0.022 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 LlaMI restriction endonuclease DUF2481 PF10654.9 GAN04424.1 - 0.063 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Med2 PF11214.8 GAN04424.1 - 0.29 11.3 3.3 8.9 6.5 1.2 2.4 1 1 1 2 2 2 0 Mediator complex subunit 2 Bromodomain PF00439.25 GAN04425.1 - 7.6e-17 61.2 0.1 2e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 GAN04425.1 - 7.6e-14 51.7 1.5 2.4e-08 33.7 0.4 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04425.1 - 5e-07 29.3 2.3 0.017 14.4 1.5 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GAN04425.1 - 0.013 14.9 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_28 PF00295.17 GAN04426.1 - 5.5e-62 209.7 19.8 7.6e-62 209.2 19.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PuR_N PF09182.10 GAN04426.1 - 0.23 11.4 1.0 0.83 9.6 0.3 2.2 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Iron_permease PF04120.12 GAN04427.1 - 8.1e-42 142.0 7.0 1.4e-16 60.5 0.3 4.2 4 0 0 4 4 4 4 Low affinity iron permease CUB PF00431.20 GAN04427.1 - 0.065 13.6 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 0 CUB domain Methyltransf_11 PF08241.12 GAN04428.1 - 2.3e-15 57.0 0.0 7e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN04428.1 - 5e-14 52.8 0.0 4.3e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN04428.1 - 4.5e-09 36.3 0.0 6.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN04428.1 - 1.2e-05 26.0 0.0 2.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN04428.1 - 0.00023 21.1 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN04428.1 - 0.0089 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 GAN04428.1 - 0.13 12.1 0.0 1.1 9.1 0.0 2.1 2 1 0 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 GAN04428.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW H2TH PF06831.14 GAN04430.1 - 3.6e-19 68.5 0.0 7.7e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 GAN04430.1 - 4.9e-13 49.7 0.9 2.6e-12 47.4 0.0 2.5 2 1 1 3 3 3 1 Formamidopyrimidine-DNA glycosylase N-terminal domain PGA2 PF07543.12 GAN04430.1 - 0.16 12.0 9.6 0.3 11.1 9.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 adh_short PF00106.25 GAN04431.1 - 9.5e-40 136.1 0.0 7.6e-39 133.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN04431.1 - 3.2e-23 82.5 0.0 2.2e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN04431.1 - 1.3e-08 35.0 0.1 8.2e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 KR domain Pyr_redox_2 PF07992.14 GAN04431.1 - 0.00046 19.5 0.1 0.00091 18.5 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HLH PF00010.26 GAN04432.1 - 1e-10 41.4 4.4 2.5e-10 40.1 0.7 2.7 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain SEO_C PF14577.6 GAN04432.1 - 0.04 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus SSP160 PF06933.11 GAN04433.1 - 0.02 13.1 11.4 0.028 12.6 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 GAN04433.1 - 1.9 8.4 17.7 2.6 8.0 17.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Sec7 PF01369.20 GAN04434.1 - 7.1e-31 107.3 1.7 2e-30 105.9 1.7 1.7 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 GAN04434.1 - 1.7e-23 83.2 1.0 9.6e-23 80.8 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAN04434.1 - 7.7e-05 23.2 0.0 0.0014 19.1 0.0 3.0 1 1 0 1 1 1 1 PH domain SR-25 PF10500.9 GAN04434.1 - 0.0091 15.6 13.4 0.0091 15.6 13.4 3.7 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein DUF4362 PF14275.6 GAN04434.1 - 0.56 10.5 3.4 0.84 9.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4362) NTF2 PF02136.20 GAN04434.1 - 0.7 10.5 0.0 0.7 10.5 0.0 3.0 3 1 0 3 3 3 0 Nuclear transport factor 2 (NTF2) domain UQ_con PF00179.26 GAN04435.1 - 3.8e-39 133.6 0.0 4.3e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAN04435.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B 120_Rick_ant PF12574.8 GAN04436.1 - 0.059 12.6 2.2 0.07 12.3 0.4 2.0 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen Myb_DNA-binding PF00249.31 GAN04437.1 - 1.4e-10 41.2 0.0 0.00015 21.9 0.0 3.1 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN04437.1 - 1.7e-06 28.2 2.4 0.0033 17.6 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain PARM PF17061.5 GAN04437.1 - 4.1 7.5 16.5 6.9 6.7 16.5 1.2 1 0 0 1 1 1 0 PARM Bromodomain PF00439.25 GAN04438.1 - 2e-15 56.6 0.5 4.3e-15 55.6 0.5 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GAN04438.1 - 3e-08 33.9 0.0 3e-08 33.9 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN04438.1 - 4.9e-05 23.3 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN04438.1 - 0.00032 21.0 0.1 0.00072 19.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCAF_N PF06466.11 GAN04438.1 - 0.0021 17.7 0.5 0.0051 16.4 0.5 1.6 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Sedlin_N PF04628.13 GAN04439.1 - 1.3e-46 157.9 1.7 1.6e-46 157.7 1.7 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAN04439.1 - 4.4e-11 42.9 0.6 6.2e-11 42.4 0.5 1.4 2 0 0 2 2 2 1 Sybindin-like family DUF2009 PF09418.10 GAN04440.1 - 5.6e-213 708.1 0.1 6.6e-213 707.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 GAN04440.1 - 0.00019 21.5 8.0 0.00019 21.5 8.0 2.0 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 GAN04440.1 - 0.04 14.2 5.6 0.11 12.8 5.6 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain NOB1_Zn_bind PF08772.11 GAN04440.1 - 0.22 11.7 3.1 0.59 10.3 3.1 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like IBR PF01485.21 GAN04440.1 - 0.41 10.9 8.5 1.7 9.0 8.5 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain CP2 PF04516.15 GAN04441.1 - 6.5e-53 179.4 0.5 1.4e-52 178.3 0.5 1.5 1 0 0 1 1 1 1 CP2 transcription factor DUF948 PF06103.11 GAN04442.1 - 0.0034 17.6 0.8 0.58 10.5 0.2 2.8 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) MscS_TM PF12794.7 GAN04442.1 - 0.045 12.6 0.1 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HU-HIG PF18291.1 GAN04442.1 - 0.051 13.7 0.2 3.6 7.7 0.1 2.3 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif ApoLp-III PF07464.11 GAN04442.1 - 0.2 11.8 3.6 0.75 9.9 0.4 2.9 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TMP_2 PF06791.13 GAN04442.1 - 0.21 11.2 3.1 0.53 9.9 0.1 2.6 3 1 0 3 3 3 0 Prophage tail length tape measure protein YtzH PF14165.6 GAN04442.1 - 0.31 11.4 3.2 5.7 7.4 0.0 3.2 3 0 0 3 3 3 0 YtzH-like protein HIP1_clath_bdg PF16515.5 GAN04442.1 - 3.6 8.3 7.4 6.2 7.5 0.1 3.1 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fumble PF03630.14 GAN04443.1 - 2.6e-121 404.9 0.5 3.7e-121 404.3 0.5 1.2 1 0 0 1 1 1 1 Fumble Syntaxin_2 PF14523.6 GAN04444.1 - 2.2e-29 101.8 6.4 2.2e-29 101.8 6.4 3.1 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 GAN04444.1 - 3.2e-10 39.8 2.0 3.2e-10 39.8 2.0 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 GAN04444.1 - 2.7e-09 37.0 17.4 2.7e-09 37.0 17.4 2.0 2 1 0 2 2 2 1 Syntaxin EMC3_TMCO1 PF01956.16 GAN04444.1 - 0.0013 18.5 1.5 0.048 13.4 1.5 2.1 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like CEP209_CC5 PF16574.5 GAN04444.1 - 0.0052 16.9 13.2 0.011 16.0 13.0 1.7 1 1 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 MCPsignal PF00015.21 GAN04444.1 - 0.056 13.3 0.5 0.056 13.3 0.5 2.8 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UL45 PF05473.12 GAN04444.1 - 0.17 11.5 0.1 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like LMBR1 PF04791.16 GAN04444.1 - 0.37 9.7 9.4 1.8 7.4 0.1 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4044 PF13253.6 GAN04444.1 - 0.95 9.0 2.9 2.5 7.7 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) FlaC_arch PF05377.11 GAN04444.1 - 2.1 8.8 6.9 0.56 10.6 0.4 3.3 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 GAN04444.1 - 2.3 6.7 6.8 0.97 7.9 4.2 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 GAN04444.1 - 3.8 7.7 24.7 5.5 7.2 22.4 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF883 PF05957.13 GAN04444.1 - 7.1 7.3 7.9 3.5e+02 1.9 0.0 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TAF8_C PF10406.9 GAN04444.1 - 8.8 7.0 8.1 2 9.0 0.7 3.1 3 1 1 4 4 4 0 Transcription factor TFIID complex subunit 8 C-term Metallophos PF00149.28 GAN04445.1 - 1.7e-11 45.0 1.4 3.3e-11 44.1 1.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase E1-E2_ATPase PF00122.20 GAN04446.1 - 1.2e-50 171.6 0.1 1.2e-50 171.6 0.1 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 GAN04446.1 - 9.6e-16 58.7 1.4 6.4e-15 56.0 1.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN04446.1 - 5.3e-14 51.7 0.1 1.4e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN04446.1 - 7.5e-05 22.6 1.0 0.00012 21.9 0.4 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN04446.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) UDPGT PF00201.18 GAN04448.1 - 6.9e-31 107.6 0.0 1.6e-30 106.4 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN04448.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PseudoU_synth_1 PF01416.20 GAN04448.1 - 0.13 12.7 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridine synthase ACT_7 PF13840.6 GAN04449.1 - 5e-29 99.9 0.0 6.2e-15 54.7 0.0 2.8 3 0 0 3 3 3 2 ACT domain Castor1_N PF18700.1 GAN04449.1 - 5.1e-05 23.0 0.8 0.002 17.9 0.2 2.4 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Telomere_reg-2 PF10193.9 GAN04450.1 - 1.3e-23 83.5 0.0 4.9e-23 81.7 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein Drc1-Sld2 PF11719.8 GAN04450.1 - 0.14 11.7 6.2 0.21 11.1 6.2 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 GAN04450.1 - 0.29 9.3 13.4 0.45 8.7 13.4 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAN04450.1 - 0.79 7.9 9.5 1.3 7.2 9.5 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GAN04450.1 - 1 8.7 14.9 1.5 8.1 14.9 1.1 1 0 0 1 1 1 0 SDA1 ETS_PEA3_N PF04621.13 GAN04451.1 - 0.055 13.3 0.8 0.13 12.1 0.8 1.6 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Aldedh PF00171.22 GAN04452.1 - 2.7e-117 392.1 0.0 3.3e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DNA_pol_A_exo1 PF01612.20 GAN04453.1 - 1.2e-19 70.6 0.4 3.4e-19 69.2 0.1 1.8 2 0 0 2 2 2 1 3'-5' exonuclease His_kinase PF06580.13 GAN04453.1 - 0.071 13.4 0.3 0.33 11.3 0.1 2.3 2 0 0 2 2 2 0 Histidine kinase DUF4250 PF14056.6 GAN04453.1 - 0.095 12.7 0.5 0.66 10.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Macoilin PF09726.9 GAN04453.1 - 0.46 9.0 5.4 0.75 8.3 5.4 1.2 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 GAN04454.1 - 0.0018 17.2 16.3 0.0018 17.2 16.3 3.1 1 1 1 2 2 2 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 GAN04454.1 - 0.013 15.5 26.5 0.65 10.0 13.5 3.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 GAN04454.1 - 0.019 14.2 39.5 0.16 11.1 14.8 3.5 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Synaptonemal_3 PF15191.6 GAN04454.1 - 0.089 12.6 3.9 0.1 12.4 1.2 2.3 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 ABC_tran_CTD PF16326.5 GAN04454.1 - 0.28 11.4 21.2 0.45 10.8 6.3 3.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain DASH_Hsk3 PF08227.11 GAN04454.1 - 0.35 11.3 4.4 28 5.2 1.1 3.8 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like RPW8 PF05659.11 GAN04454.1 - 1.1 8.9 8.0 0.087 12.5 1.3 2.6 2 2 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1664 PF07889.12 GAN04454.1 - 8.1 6.5 20.9 0.042 13.9 6.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAN04454.1 - 9 4.7 9.3 15 4.0 9.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family SAP PF02037.27 GAN04456.1 - 1.8e-11 43.5 0.1 3e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 SAP domain DUF4287 PF14117.6 GAN04456.1 - 0.02 15.0 0.0 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) LETM1 PF07766.13 GAN04456.1 - 0.031 13.6 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 LETM1-like protein Codanin-1_C PF15296.6 GAN04456.1 - 2.2 8.4 8.0 5.2 7.2 0.1 3.2 3 0 0 3 3 3 0 Codanin-1 C-terminus Fip1 PF05182.13 GAN04458.1 - 4.4e-25 86.9 0.7 8.7e-25 86.0 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif CRM1_C PF08767.11 GAN04459.1 - 5.5e-73 245.9 8.3 5.5e-73 245.9 8.3 3.1 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 GAN04459.1 - 7.8e-31 107.2 4.4 7.8e-31 107.2 4.4 4.5 3 3 3 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAN04459.1 - 1e-23 82.7 0.0 4.1e-23 80.8 0.0 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 GAN04459.1 - 1.4e-12 46.9 3.1 3.4e-12 45.7 0.6 2.8 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat CRM1_repeat_3 PF18787.1 GAN04459.1 - 3.7e-12 46.2 0.7 1.4e-11 44.3 0.7 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 GAN04459.1 - 0.00076 19.4 0.1 0.0066 16.3 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Meth_synt_2 PF01717.18 GAN04460.1 - 0.21 10.8 0.0 0.26 10.5 0.0 1.0 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain NatB_MDM20 PF09797.9 GAN04461.1 - 1e-109 367.0 8.8 2.1e-109 366.0 8.8 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 GAN04461.1 - 0.012 16.1 0.1 0.012 16.1 0.1 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 GAN04461.1 - 0.013 15.9 0.7 0.17 12.3 0.0 3.1 2 2 1 3 3 3 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 GAN04461.1 - 0.025 15.0 0.5 1.9 8.9 0.0 3.1 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation DASH_Dad4 PF08650.10 GAN04461.1 - 0.069 13.1 0.5 0.35 10.9 0.3 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad4 TPR_15 PF13429.6 GAN04461.1 - 2.5 7.2 14.5 5.3 6.2 0.0 4.8 3 2 2 6 6 6 0 Tetratricopeptide repeat Nup35_RRM_2 PF14605.6 GAN04462.1 - 0.16 12.0 0.1 0.48 10.5 0.1 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif IBN_N PF03810.19 GAN04463.1 - 1.1e-16 60.4 0.5 7.6e-16 57.8 0.2 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 GAN04463.1 - 5.1e-10 38.7 0.0 2e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 GAN04463.1 - 7.8e-05 22.8 0.1 7.8e-05 22.8 0.1 3.6 5 1 0 5 5 5 1 Exportin 1-like protein NUC173 PF08161.12 GAN04463.1 - 0.0013 18.5 0.5 0.017 14.8 0.1 2.7 3 0 0 3 3 3 1 NUC173 domain RIX1 PF08167.12 GAN04463.1 - 0.066 12.9 7.2 0.12 12.1 0.2 3.8 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Ribosomal_S2 PF00318.20 GAN04464.1 - 2e-62 210.2 0.0 2e-35 122.0 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S2 Xan_ur_permease PF00860.20 GAN04467.1 - 8.1e-23 80.7 33.5 3.9e-21 75.2 33.5 2.7 1 1 0 1 1 1 1 Permease family DUF3956 PF13104.6 GAN04467.1 - 0.096 12.9 3.3 1.9 8.8 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3956) Acyltransferase PF01553.21 GAN04468.1 - 4.3e-08 32.9 0.5 1.2e-05 25.0 0.2 2.7 1 1 1 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 GAN04469.1 - 5.5e-10 39.2 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Proteasom_PSMB PF10508.9 GAN04470.1 - 8.4e-62 209.3 6.0 9.7e-62 209.1 6.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 GAN04470.1 - 3.4e-06 25.9 0.5 7.1e-06 24.8 0.5 1.4 1 0 0 1 1 1 1 Adaptin N terminal region RICTOR_M PF14666.6 GAN04470.1 - 0.00048 19.8 0.3 0.046 13.5 0.0 3.4 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 GAN04470.1 - 0.0032 17.7 0.5 3.1 8.1 0.1 3.4 2 1 2 4 4 4 3 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 GAN04470.1 - 0.015 15.6 0.0 1.7 9.1 0.0 3.2 2 1 1 3 3 3 0 HEAT repeats PSDC PF12588.8 GAN04470.1 - 0.1 12.6 0.3 1.8 8.5 0.0 2.7 3 0 0 3 3 3 0 Phophatidylserine decarboxylase Cnd1 PF12717.7 GAN04470.1 - 0.42 10.6 4.8 1.5 8.8 1.9 3.1 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 GAN04471.1 - 6e-52 176.6 0.0 2e-51 174.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04471.1 - 4e-28 98.4 0.0 1.3e-27 96.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAN04471.1 - 0.0025 17.5 1.1 0.2 11.3 0.0 3.1 2 1 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Metallophos PF00149.28 GAN04472.1 - 2.9e-38 132.5 0.0 3.7e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN04472.1 - 7.7e-23 80.7 0.8 1.3e-22 80.0 0.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Aa_trans PF01490.18 GAN04473.1 - 9.9e-59 199.1 22.3 1.2e-58 198.7 22.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aha1_N PF09229.11 GAN04474.1 - 2.5e-33 115.2 0.0 5.3e-33 114.1 0.0 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 GAN04474.1 - 1.4e-16 60.9 0.6 2.3e-16 60.2 0.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein CttA_N PF18244.1 GAN04474.1 - 0.13 12.7 1.1 3.3 8.2 0.0 3.6 5 0 0 5 5 5 0 Cellulose-binding protein CttA N-terminal domain Bee_toxin PF17454.2 GAN04474.1 - 0.22 11.6 3.0 0.38 10.8 3.0 1.4 1 0 0 1 1 1 0 Honey bee toxin DUF727 PF05303.12 GAN04475.1 - 1.1e-10 41.4 0.0 3.2e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TFIIA PF03153.13 GAN04475.1 - 8.7 6.2 12.9 10 6.0 12.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.27 GAN04476.1 - 4.7e-15 55.7 0.0 8.8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GAN04476.1 - 3.3e-11 43.1 0.7 2e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase UL17 PF17640.2 GAN04476.1 - 0.023 14.7 0.2 0.058 13.4 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized UL17 DUF3450 PF11932.8 GAN04476.1 - 0.11 11.8 2.1 0.23 10.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Herpes_BLRF2 PF05812.12 GAN04476.1 - 0.16 12.2 0.4 0.37 10.9 0.4 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Csm1_N PF18504.1 GAN04476.1 - 0.31 11.4 1.2 0.75 10.2 1.2 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain zf-3CxxC_2 PF17180.4 GAN04477.1 - 4.2e-11 43.4 8.2 1.6e-10 41.5 8.2 2.0 1 0 0 1 1 1 1 Zinc-binding domain UPF0515 PF15135.6 GAN04477.1 - 0.24 10.7 5.4 0.54 9.6 3.4 2.3 3 0 0 3 3 3 0 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 GAN04477.1 - 2.2 8.8 12.5 96 3.5 12.5 2.8 1 1 0 1 1 1 0 Zinc-binding domain Frag1 PF10277.9 GAN04478.1 - 6.1e-37 127.3 12.6 6.1e-37 127.3 12.6 3.4 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family AAA PF00004.29 GAN04479.1 - 1.1e-96 320.3 0.0 6e-49 165.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN04479.1 - 5.5e-22 77.3 1.1 1e-10 41.3 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 GAN04479.1 - 1.5e-16 60.6 0.0 3.2e-09 36.7 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAN04479.1 - 3.6e-13 50.2 1.4 0.001 19.5 0.0 4.5 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 GAN04479.1 - 1.5e-12 47.6 0.8 4.4e-05 23.5 0.0 4.3 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAN04479.1 - 1.6e-11 44.6 0.0 0.00012 22.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAN04479.1 - 6.4e-10 39.4 0.5 0.019 15.3 0.1 4.7 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 GAN04479.1 - 1.3e-09 38.4 0.0 0.00086 19.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 GAN04479.1 - 9.7e-09 34.9 0.0 0.00029 20.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 GAN04479.1 - 2.6e-08 34.0 0.0 0.002 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAN04479.1 - 7.5e-08 32.7 0.0 0.023 15.1 0.0 2.9 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 GAN04479.1 - 4.5e-07 29.8 0.0 0.023 14.4 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 GAN04479.1 - 6.3e-07 29.4 0.3 0.087 12.7 0.0 4.1 3 1 0 3 3 3 2 NACHT domain AAA_18 PF13238.6 GAN04479.1 - 1e-06 29.3 0.0 0.024 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAN04479.1 - 2e-06 27.5 1.7 2.7 7.5 0.0 4.4 3 1 1 4 4 4 2 AAA domain Zeta_toxin PF06414.12 GAN04479.1 - 2.4e-06 27.0 0.0 0.065 12.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.27 GAN04479.1 - 3e-06 27.8 0.1 0.23 12.0 0.0 3.5 3 0 0 3 3 3 2 ABC transporter AAA_7 PF12775.7 GAN04479.1 - 3.1e-06 26.8 0.0 0.18 11.3 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAN04479.1 - 5.3e-06 26.0 0.1 0.066 12.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAN04479.1 - 8.7e-06 26.1 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 GAN04479.1 - 1.2e-05 25.3 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 GAN04479.1 - 2.2e-05 24.7 0.0 0.0099 16.0 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.11 GAN04479.1 - 3.7e-05 23.6 0.1 0.24 11.2 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 GAN04479.1 - 3.8e-05 23.9 0.0 0.47 10.6 0.0 3.6 3 0 0 3 3 3 1 Shikimate kinase DUF815 PF05673.13 GAN04479.1 - 3.8e-05 23.0 0.0 0.016 14.4 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 GAN04479.1 - 7.4e-05 23.2 0.3 0.29 11.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 GAN04479.1 - 8.9e-05 21.9 0.0 1 8.6 0.0 3.4 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 GAN04479.1 - 9e-05 22.2 0.0 0.28 10.9 0.0 3.5 4 0 0 4 4 3 1 Sigma-54 interaction domain Rad17 PF03215.15 GAN04479.1 - 0.00021 21.3 0.0 0.68 9.8 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain ATPase_2 PF01637.18 GAN04479.1 - 0.00021 21.3 0.0 2.4 8.0 0.0 3.7 2 2 0 2 2 2 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 GAN04479.1 - 0.00036 20.3 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 GAN04479.1 - 0.00044 19.5 0.0 0.83 8.8 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 GAN04479.1 - 0.00047 19.9 0.0 0.46 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 GAN04479.1 - 0.00065 19.4 0.0 0.49 10.0 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 GAN04479.1 - 0.0012 19.1 3.1 0.2 12.0 0.9 3.4 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 GAN04479.1 - 0.0018 17.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 CPT PF07931.12 GAN04479.1 - 0.0021 17.9 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Vps4_C PF09336.10 GAN04479.1 - 0.0031 17.5 0.4 3.2 7.8 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_11 PF13086.6 GAN04479.1 - 0.0036 17.1 6.1 0.25 11.1 0.0 3.1 4 0 0 4 4 2 2 AAA domain NTPase_1 PF03266.15 GAN04479.1 - 0.0042 17.0 0.1 4.2 7.2 0.0 3.0 2 1 0 2 2 2 0 NTPase Bac_DnaA PF00308.18 GAN04479.1 - 0.0043 16.9 0.0 4.3 7.1 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 GAN04479.1 - 0.0045 17.1 0.1 1.7 8.7 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain TniB PF05621.11 GAN04479.1 - 0.0052 16.2 0.0 2.5 7.5 0.0 3.3 3 1 0 3 3 3 1 Bacterial TniB protein PhoH PF02562.16 GAN04479.1 - 0.011 15.1 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AFG1_ATPase PF03969.16 GAN04479.1 - 0.012 14.5 0.0 2.1 7.1 0.0 2.6 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.9 GAN04479.1 - 0.023 14.4 0.0 12 5.7 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 GAN04479.1 - 0.049 13.4 0.0 7.3 6.2 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase DUF3708 PF12501.8 GAN04479.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Ribosomal_L18A PF01775.17 GAN04480.1 - 1.8e-51 173.3 1.5 2.3e-51 173.0 1.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_L7Ae PF01248.26 GAN04481.1 - 1.8e-14 53.2 1.1 3.8e-14 52.2 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cyclin_N PF00134.23 GAN04481.1 - 2.9e-08 33.5 0.0 1e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN04481.1 - 1.9e-06 28.3 2.1 0.017 15.5 0.3 3.2 2 1 0 3 3 3 2 Cyclin ATPase_2 PF01637.18 GAN04481.1 - 0.063 13.2 0.7 0.11 12.4 0.7 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SIP1 PF04938.12 GAN04482.1 - 1.5e-34 119.6 0.4 1.8e-34 119.4 0.4 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Utp12 PF04003.12 GAN04482.1 - 0.0013 19.1 0.5 0.002 18.4 0.5 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family p450 PF00067.22 GAN04483.1 - 3e-78 263.6 0.0 3.7e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gram_pos_anchor PF00746.21 GAN04483.1 - 0.096 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif M20_dimer PF07687.14 GAN04484.1 - 1.3e-10 41.2 0.0 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAN04484.1 - 3.9e-09 36.5 0.3 6.9e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Barwin PF00967.17 GAN04485.1 - 0.032 14.1 0.2 0.06 13.2 0.2 1.5 1 0 0 1 1 1 0 Barwin family NIR_SIR PF01077.22 GAN04486.1 - 1.8e-51 173.8 0.1 1.4e-45 154.7 0.1 2.8 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 GAN04486.1 - 2.6e-31 108.7 0.1 7.1e-31 107.3 0.1 1.8 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 GAN04486.1 - 6.6e-27 93.2 0.0 6.5e-14 51.5 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 GAN04486.1 - 2.6e-20 73.2 1.4 6.3e-20 71.9 0.6 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 GAN04486.1 - 3.9e-11 43.2 0.0 1.9e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Flavodoxin_5 PF12724.7 GAN04486.1 - 0.024 14.9 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 Flavodoxin domain Pilus_CpaD PF09476.10 GAN04486.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pkinase PF00069.25 GAN04487.1 - 5.7e-70 235.7 0.0 5.7e-70 235.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04487.1 - 6.1e-39 133.8 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAN04487.1 - 2.4e-10 40.1 0.1 7.3e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 GAN04487.1 - 6.2e-08 32.3 0.1 1.2e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAN04487.1 - 0.014 15.0 0.3 0.014 15.0 0.3 2.3 3 0 0 3 3 3 0 RIO1 family APH PF01636.23 GAN04487.1 - 0.029 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN04487.1 - 0.054 12.8 0.2 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM14 PF12701.7 GAN04489.1 - 3.5e-31 107.1 0.7 9.3e-31 105.8 0.1 2.1 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.10 GAN04489.1 - 1.6e-10 41.8 14.8 1.6e-10 41.8 14.8 7.0 5 2 2 7 7 7 1 FDF domain SM-ATX PF14438.6 GAN04489.1 - 3.9e-07 30.1 0.0 1.4e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LRR_6 PF13516.6 GAN04490.1 - 8.6e-15 53.5 33.3 0.011 15.7 3.6 10.5 9 2 1 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.33 GAN04490.1 - 1.6e-07 30.9 20.0 2 9.3 0.3 9.2 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_4 PF12799.7 GAN04490.1 - 3e-05 24.3 32.7 0.18 12.2 1.3 6.9 3 1 5 8 8 8 6 Leucine Rich repeats (2 copies) Psu PF07455.11 GAN04490.1 - 0.022 14.4 0.2 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) LRR_8 PF13855.6 GAN04490.1 - 1.8 8.4 32.3 10 6.0 8.9 6.7 4 2 2 6 6 6 0 Leucine rich repeat Amino_oxidase PF01593.24 GAN04491.1 - 5.4e-24 85.3 0.0 8.2e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAN04491.1 - 2.2e-14 53.4 0.1 5.8e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAN04491.1 - 2.7e-13 50.2 0.0 7.1e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN04491.1 - 6.6e-10 38.7 0.1 2.3e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAN04491.1 - 5.2e-06 25.8 2.1 5.8e-05 22.4 1.3 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAN04491.1 - 7.8e-06 25.5 0.0 3.1e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAN04491.1 - 6.8e-05 22.9 2.2 0.0021 18.1 0.3 2.9 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAN04491.1 - 0.00072 20.1 4.1 0.024 15.2 1.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAN04491.1 - 0.0012 18.2 0.2 0.0023 17.2 0.2 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAN04491.1 - 0.0031 16.6 3.6 0.011 14.9 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAN04491.1 - 0.0049 16.2 0.1 0.011 15.0 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAN04491.1 - 0.0062 15.3 0.5 0.0095 14.7 0.2 1.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 GAN04491.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAN04491.1 - 0.017 14.0 1.3 0.067 12.0 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 GAN04491.1 - 0.023 14.3 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAN04491.1 - 0.04 13.8 1.0 0.096 12.6 1.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAN04491.1 - 0.045 13.0 0.4 0.077 12.3 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 GAN04491.1 - 0.076 12.7 0.5 0.17 11.5 0.5 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 GAN04491.1 - 0.09 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 GAN04491.1 - 0.1 11.6 2.2 0.12 11.4 0.3 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein adh_short PF00106.25 GAN04491.1 - 0.13 11.7 0.9 0.2 11.1 0.9 1.3 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 GAN04491.1 - 0.21 12.2 1.0 2.4 8.8 0.4 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 GAN04491.1 - 0.22 11.8 1.5 0.33 11.2 0.3 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 GAN04491.1 - 0.39 9.9 4.5 0.34 10.1 1.3 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SQS_PSY PF00494.19 GAN04492.1 - 9.5e-59 199.0 0.5 1.3e-58 198.6 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Abhydrolase_1 PF00561.20 GAN04494.1 - 3.2e-24 86.0 0.0 1.9e-22 80.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN04494.1 - 5.7e-21 76.1 0.0 7.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN04494.1 - 1.3e-14 54.1 0.0 2.2e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAN04494.1 - 1.4e-07 31.5 0.1 1e-05 25.4 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 GAN04494.1 - 3.5e-06 27.3 0.0 5.5e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 GAN04494.1 - 6.6e-06 25.0 0.0 0.013 14.2 0.0 2.1 2 0 0 2 2 2 2 Ndr family Palm_thioest PF02089.15 GAN04494.1 - 0.00044 20.2 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 GAN04494.1 - 0.00046 19.9 0.0 0.0015 18.2 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.16 GAN04494.1 - 0.0012 18.4 0.1 0.03 13.9 0.0 2.3 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Peptidase_S10 PF00450.22 GAN04494.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.3 1 1 0 1 1 1 0 Serine carboxypeptidase DUF676 PF05057.14 GAN04494.1 - 0.034 13.7 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 GAN04494.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase Nucleotid_trans PF03407.16 GAN04496.1 - 1.4e-20 74.2 0.1 2.2e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase ACBP PF00887.19 GAN04497.1 - 2e-19 69.6 0.0 3.8e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF648 PF04890.13 GAN04497.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) TauD PF02668.16 GAN04498.1 - 1.2e-56 192.5 0.2 1.9e-56 191.8 0.1 1.3 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 GAN04499.1 - 3.7e-52 177.8 0.4 4.6e-52 177.4 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_S27e PF01667.17 GAN04500.1 - 9.6e-29 98.9 3.6 9.6e-29 98.9 3.6 2.1 2 0 0 2 2 2 1 Ribosomal protein S27 Acyltransferase PF01553.21 GAN04500.1 - 4e-11 42.7 0.0 8.9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase TF_Zn_Ribbon PF08271.12 GAN04500.1 - 0.0069 15.9 3.1 0.014 14.8 3.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-C2HC5 PF06221.13 GAN04500.1 - 0.78 9.8 5.9 0.24 11.4 1.2 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type IBR PF01485.21 GAN04500.1 - 0.86 9.9 3.0 1 9.6 0.9 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 GAN04500.1 - 1.3 9.0 5.5 0.73 9.8 2.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Acetyltransf_1 PF00583.25 GAN04501.1 - 2e-06 28.0 0.0 3.5e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN04501.1 - 0.00013 22.3 0.0 0.00021 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN04501.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAN04501.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN04501.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 GAN04501.1 - 0.15 12.8 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hydrolase_4 PF12146.8 GAN04502.1 - 1.1e-14 54.3 0.1 1.6e-11 44.0 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN04502.1 - 7.6e-11 42.1 0.0 3.3e-09 36.8 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAN04502.1 - 4.5e-08 32.8 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 GAN04502.1 - 1.8e-06 26.9 0.1 0.22 10.2 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 GAN04502.1 - 0.00042 20.0 0.0 0.065 12.8 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.12 GAN04502.1 - 0.00063 18.8 0.0 0.00086 18.4 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 GAN04502.1 - 0.0029 17.6 0.0 0.035 14.0 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 GAN04502.1 - 0.0056 17.3 0.0 0.0071 17.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 GAN04502.1 - 0.047 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 GAN04502.1 - 0.11 12.0 0.0 1 8.8 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family SAM_2 PF07647.17 GAN04504.1 - 1e-14 54.4 0.5 6e-14 51.9 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN04504.1 - 1.3e-10 41.5 0.7 1.1e-09 38.6 0.3 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 GAN04504.1 - 1.3e-10 41.7 0.0 2.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF2464 PF10240.9 GAN04504.1 - 0.0051 16.4 2.6 0.0051 16.4 2.6 2.8 3 0 0 3 3 3 1 Multivesicular body subunit 12 ATF7IP_BD PF16788.5 GAN04504.1 - 4.5 7.3 24.9 8.2 6.5 4.3 2.5 2 0 0 2 2 2 0 ATF-interacting protein binding domain ABC_tran PF00005.27 GAN04505.1 - 9.3e-46 155.7 0.0 5.4e-23 82.0 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAN04505.1 - 7.9e-15 55.4 0.3 3.2e-05 23.9 0.1 4.3 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN04505.1 - 2.6e-14 53.2 0.0 4e-05 23.2 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN04505.1 - 2.3e-08 34.4 0.7 0.073 13.3 0.0 4.8 5 0 0 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 GAN04505.1 - 1.2e-07 31.8 0.0 0.00093 19.1 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 GAN04505.1 - 1.5e-07 31.8 0.0 0.0085 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAN04505.1 - 6.4e-07 29.5 0.0 0.0067 16.5 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA PF00004.29 GAN04505.1 - 6.5e-07 29.8 0.0 0.1 13.0 0.0 4.0 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAN04505.1 - 8.2e-07 28.7 0.0 0.028 14.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 GAN04505.1 - 2.2e-06 28.2 0.1 0.035 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 GAN04505.1 - 2.5e-06 26.7 0.1 0.013 14.5 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAN04505.1 - 9e-06 26.2 0.2 0.023 15.1 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 GAN04505.1 - 1.4e-05 24.9 0.0 0.75 9.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 GAN04505.1 - 3.4e-05 24.2 0.0 0.43 11.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Chromo PF00385.24 GAN04505.1 - 5.8e-05 22.9 0.2 0.00018 21.3 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 GAN04505.1 - 5.9e-05 22.9 0.0 0.24 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain DUF815 PF05673.13 GAN04505.1 - 6.6e-05 22.2 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAN04505.1 - 7.3e-05 23.0 0.0 0.31 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAN04505.1 - 0.00021 21.3 0.0 0.38 10.7 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_14 PF13173.6 GAN04505.1 - 0.00094 19.2 0.0 0.88 9.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 GAN04505.1 - 0.0011 19.1 0.1 0.43 10.6 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain Rad17 PF03215.15 GAN04505.1 - 0.0012 18.9 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain PduV-EutP PF10662.9 GAN04505.1 - 0.0015 18.3 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.6 GAN04505.1 - 0.0032 17.8 0.4 11 6.5 0.0 3.6 3 0 0 3 3 3 0 HEAT repeats AAA_24 PF13479.6 GAN04505.1 - 0.0079 15.9 0.0 0.85 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 GAN04505.1 - 0.008 15.9 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain CLP1_P PF16575.5 GAN04505.1 - 0.0084 15.9 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_23 PF13476.6 GAN04505.1 - 0.0085 16.6 18.2 0.032 14.7 0.0 4.0 4 1 0 4 4 3 2 AAA domain AAA_27 PF13514.6 GAN04505.1 - 0.0089 15.6 1.0 4.4 6.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 GAN04505.1 - 0.0098 15.1 0.1 0.82 8.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 GAN04505.1 - 0.012 15.6 0.2 6.2 6.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ParcG PF10274.9 GAN04505.1 - 0.012 15.7 0.2 3.9 7.5 0.0 2.6 1 1 1 2 2 2 0 Parkin co-regulated protein Dynamin_N PF00350.23 GAN04505.1 - 0.016 15.3 0.0 1.2 9.1 0.0 2.9 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 GAN04505.1 - 0.018 15.2 0.0 2 8.7 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 GAN04505.1 - 0.02 14.4 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAN04505.1 - 0.021 14.7 0.1 2.4 8.0 0.1 2.8 2 0 0 2 2 2 0 NTPase PRK PF00485.18 GAN04505.1 - 0.031 14.0 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 GAN04505.1 - 0.033 13.8 0.3 5.6 6.5 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 GAN04505.1 - 0.034 13.4 0.1 9 5.5 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 GAN04505.1 - 0.036 14.0 1.7 4.4 7.2 0.0 3.1 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 GAN04505.1 - 0.041 13.6 0.0 0.85 9.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FeoB_N PF02421.18 GAN04505.1 - 0.06 12.9 0.0 6.9 6.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B IstB_IS21 PF01695.17 GAN04505.1 - 0.062 13.0 0.0 24 4.6 0.0 3.2 4 0 0 4 4 2 0 IstB-like ATP binding protein TsaE PF02367.17 GAN04505.1 - 0.08 12.9 0.0 9.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 4HB PF17947.1 GAN04505.1 - 0.081 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 Four helical bundle domain HEAT PF02985.22 GAN04505.1 - 0.1 12.9 0.5 0.78 10.2 0.0 2.9 3 0 0 3 3 1 0 HEAT repeat Septin PF00735.18 GAN04505.1 - 0.11 11.7 0.2 36 3.5 0.0 3.2 3 0 0 3 3 3 0 Septin Cytidylate_kin PF02224.18 GAN04505.1 - 0.14 11.9 0.9 3.1 7.5 0.0 3.0 2 1 0 3 3 3 0 Cytidylate kinase U3snoRNP10 PF12397.8 GAN04505.1 - 0.17 12.2 0.2 0.47 10.8 0.2 1.8 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 ZoocinA_TRD PF16775.5 GAN04505.1 - 0.19 11.9 0.2 0.52 10.5 0.2 1.7 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme AAA_13 PF13166.6 GAN04505.1 - 0.2 10.2 3.7 10 4.6 0.0 3.4 5 0 0 5 5 3 0 AAA domain PEMT PF04191.13 GAN04506.1 - 6.2e-35 119.8 3.9 6.2e-35 119.8 3.9 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1056 PF06341.11 GAN04506.1 - 0.49 10.7 5.3 32 4.9 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) Presenilin PF01080.17 GAN04507.1 - 3.3e-79 266.5 1.1 4.6e-79 266.0 1.1 1.2 1 0 0 1 1 1 1 Presenilin MIG-14_Wnt-bd PF06664.12 GAN04507.1 - 0.00012 21.5 11.3 0.0002 20.7 11.3 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Sarcoglycan_1 PF04790.13 GAN04507.1 - 0.25 10.7 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein Baculo_PEP_C PF04513.12 GAN04508.1 - 0.022 14.8 0.9 18 5.4 0.0 4.9 4 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_7 PF13499.6 GAN04508.1 - 0.054 13.9 0.0 0.22 12.0 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair Calreticulin PF00262.18 GAN04509.1 - 1.3e-75 254.5 21.5 8.7e-59 199.2 2.6 2.6 2 1 1 3 3 3 2 Calreticulin family F-box-like PF12937.7 GAN04510.1 - 6.4e-10 38.8 0.1 1.8e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04510.1 - 1e-06 28.4 0.1 3.4e-06 26.8 0.1 2.0 1 0 0 1 1 1 1 F-box domain DsrD PF08679.11 GAN04510.1 - 0.093 13.0 0.0 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF4809 PF16067.5 GAN04511.1 - 0.18 12.0 0.5 0.2 11.8 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) Ferric_reduct PF01794.19 GAN04512.1 - 3e-20 72.6 9.1 3e-20 72.6 7.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAN04512.1 - 6.5e-14 52.3 0.0 2.6e-11 43.9 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAN04512.1 - 0.00045 20.3 0.1 0.0022 18.0 0.1 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAN04512.1 - 0.075 13.7 0.0 0.64 10.7 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain A_thal_3526 PF09713.10 GAN04512.1 - 0.12 12.7 0.1 0.39 11.0 0.1 2.0 1 1 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) C2 PF00168.30 GAN04513.1 - 3e-89 294.1 10.0 4.2e-21 75.2 0.1 6.3 6 0 0 6 6 6 6 C2 domain DUF4497 PF14924.6 GAN04513.1 - 0.1 13.1 0.1 1.3 9.5 0.0 2.9 5 0 0 5 5 5 0 Protein of unknown function (DUF4497) Urb2 PF10441.9 GAN04514.1 - 8.6e-45 153.2 1.8 8.6e-45 153.2 1.8 4.7 5 2 0 5 5 5 1 Urb2/Npa2 family CRIC_ras_sig PF10534.9 GAN04514.1 - 8.6 6.6 8.8 0.86 9.8 0.2 4.0 5 0 0 5 5 5 0 Connector enhancer of kinase suppressor of ras PTPA PF03095.15 GAN04515.1 - 7.4e-127 422.9 0.7 8.6e-127 422.7 0.7 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Asn_synthase PF00733.21 GAN04516.1 - 3.4e-73 247.3 0.0 4.8e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 GAN04516.1 - 7e-39 132.5 0.0 1.2e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAN04516.1 - 3.3e-33 114.7 0.0 7.6e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAN04516.1 - 0.0025 17.3 0.0 0.0061 16.0 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 GAN04516.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD synthase KH_7 PF17214.3 GAN04517.1 - 0.055 13.4 0.1 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 KH domain Formyl_trans_N PF00551.19 GAN04518.1 - 9.8e-52 175.3 0.2 1.1e-51 175.1 0.2 1.0 1 0 0 1 1 1 1 Formyl transferase TPPII PF12580.8 GAN04518.1 - 0.055 12.9 0.1 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II TPR_19 PF14559.6 GAN04519.1 - 3.2e-17 62.8 39.6 0.0053 17.2 0.1 8.4 5 3 4 9 9 9 7 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GAN04519.1 - 8.4e-17 61.3 3.1 8.4e-17 61.3 3.1 3.8 3 1 1 4 4 3 1 Putative TPR-like repeat TPR_14 PF13428.6 GAN04519.1 - 1.6e-15 56.5 19.6 0.16 12.9 0.0 10.8 8 3 4 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAN04519.1 - 5.6e-14 52.5 23.3 0.0036 17.9 0.5 7.6 6 1 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAN04519.1 - 9.2e-14 50.4 24.8 0.0022 18.0 0.0 10.5 11 0 0 11 11 11 3 Tetratricopeptide repeat SRP72 PF08492.12 GAN04519.1 - 1e-13 51.5 5.3 1e-13 51.5 5.3 3.2 3 0 0 3 3 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 GAN04519.1 - 4e-11 43.0 34.8 0.0019 18.4 0.5 7.5 3 2 5 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAN04519.1 - 1.5e-10 41.0 34.1 0.025 15.2 0.1 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAN04519.1 - 1.7e-09 37.1 24.2 0.043 14.0 0.1 8.1 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAN04519.1 - 2.5e-08 34.1 21.1 0.0027 18.0 3.4 7.6 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN04519.1 - 1.2e-07 31.7 8.7 1.2 9.3 0.0 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN04519.1 - 1.5e-06 27.8 17.7 0.091 12.6 0.1 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN04519.1 - 1.6e-06 27.5 33.2 0.00011 21.5 7.2 5.0 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAN04519.1 - 5.3e-06 26.5 16.9 4 8.0 0.4 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN04519.1 - 9.2e-06 25.3 11.4 0.23 11.6 0.1 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 GAN04519.1 - 2e-05 24.5 7.3 0.11 12.6 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAN04519.1 - 2.4e-05 24.5 1.0 1.5 9.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 GAN04519.1 - 0.0002 21.8 10.3 0.055 13.9 0.0 5.0 3 3 2 5 5 5 2 Bacterial transcriptional activator domain TPR_11 PF13414.6 GAN04519.1 - 0.001 18.7 3.6 0.018 14.7 0.1 7.1 9 0 0 9 9 8 2 TPR repeat TPR_MalT PF17874.1 GAN04519.1 - 0.0012 18.3 21.0 0.016 14.6 0.2 4.0 2 1 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 GAN04519.1 - 0.0031 17.3 13.6 0.25 11.2 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat PPR PF01535.20 GAN04519.1 - 0.028 14.6 0.0 34 5.0 0.0 4.3 5 0 0 5 5 4 0 PPR repeat TPR_20 PF14561.6 GAN04519.1 - 1 9.7 31.1 0.52 10.7 1.0 7.0 5 2 1 7 7 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAN04519.1 - 5.5 7.4 24.4 25 5.3 0.0 5.7 3 1 3 6 6 6 0 Alkyl sulfatase dimerisation MFS_1_like PF12832.7 GAN04520.1 - 3.4e-61 207.2 18.8 5.5e-61 206.5 18.8 1.3 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAN04520.1 - 5.5e-20 71.6 36.0 4.2e-10 39.1 20.1 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAN04520.1 - 7.7e-08 31.7 10.2 7.7e-08 31.7 10.2 2.4 2 0 0 2 2 2 1 Nucleoside H+ symporter PNTB_4TM PF12769.7 GAN04520.1 - 5.8 7.4 11.2 0.046 14.2 1.5 2.7 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Pox_Ag35 PF03286.14 GAN04520.1 - 7 6.4 9.4 7.4 6.3 1.4 2.9 3 0 0 3 3 3 0 Pox virus Ag35 surface protein HA2 PF04408.23 GAN04521.1 - 3.9e-18 65.7 0.0 3.9e-18 65.7 0.0 2.9 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAN04521.1 - 2e-14 53.9 0.0 1e-13 51.6 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAN04521.1 - 2.3e-09 37.5 0.1 6.6e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAN04521.1 - 1e-08 35.2 0.0 2.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAN04521.1 - 0.0022 18.3 1.3 0.071 13.4 0.2 3.6 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 GAN04521.1 - 0.018 15.4 0.0 0.055 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAN04521.1 - 0.04 13.0 0.1 0.076 12.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAN04521.1 - 0.12 12.9 0.7 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 GAN04521.1 - 0.46 11.0 0.0 0.46 11.0 0.0 4.6 5 0 0 5 5 5 0 AAA domain ATPase PF06745.13 GAN04521.1 - 0.46 9.8 3.0 0.66 9.3 0.0 2.5 2 0 0 2 2 2 0 KaiC Peptidase_M56 PF05569.11 GAN04522.1 - 0.065 12.4 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Pkinase PF00069.25 GAN04523.1 - 4.3e-59 200.0 0.0 7e-59 199.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04523.1 - 3e-29 102.1 0.0 4.5e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAN04523.1 - 3.8e-05 23.4 0.2 0.1 12.2 0.0 3.2 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 GAN04523.1 - 0.00048 20.8 1.2 0.00048 20.8 1.2 3.3 4 0 0 4 4 4 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAN04523.1 - 0.0076 15.6 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAN04523.1 - 0.026 14.1 0.0 0.075 12.6 0.0 1.8 1 0 0 1 1 1 0 RIO1 family PX PF00787.24 GAN04523.1 - 0.26 11.3 9.7 0.23 11.4 5.7 2.8 2 1 0 2 2 2 0 PX domain TPR_1 PF00515.28 GAN04524.1 - 2.9e-13 49.0 5.6 9.8e-05 22.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 GAN04524.1 - 4.6e-11 42.5 0.3 9.1e-11 41.6 0.3 1.6 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 GAN04524.1 - 4.3e-10 38.9 4.3 0.0049 16.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN04524.1 - 1.6e-07 30.9 0.8 0.021 15.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN04524.1 - 8.5e-05 22.6 1.0 0.035 14.3 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN04524.1 - 0.00038 21.0 0.1 0.045 14.4 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN04524.1 - 0.00087 18.9 0.2 0.021 14.5 0.1 2.9 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 GAN04524.1 - 0.0039 17.5 0.1 0.052 13.9 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN04524.1 - 0.0059 16.9 0.2 7.5 6.9 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Ubiquitin_2 PF14560.6 GAN04524.1 - 0.0079 16.6 0.1 0.0079 16.6 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin-like domain TPR_6 PF13174.6 GAN04524.1 - 0.062 14.0 1.2 11 6.9 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 GAN04524.1 - 0.076 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family RhodobacterPufX PF11511.8 GAN04525.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Aldo_ket_red PF00248.21 GAN04526.1 - 2.6e-47 161.4 0.0 3.4e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Arf PF00025.21 GAN04527.1 - 4.5e-77 257.4 0.1 5.2e-77 257.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAN04527.1 - 1.4e-15 57.6 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN04527.1 - 4.6e-14 52.3 0.0 5.3e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAN04527.1 - 2.8e-13 49.8 0.4 1.1e-08 34.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAN04527.1 - 1e-11 44.6 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAN04527.1 - 3e-10 39.9 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN04527.1 - 2.2e-06 27.8 0.0 4.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN04527.1 - 8.9e-06 25.4 0.1 7.8e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 GAN04527.1 - 0.0078 16.8 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAN04527.1 - 0.0082 16.7 0.7 0.048 14.2 0.7 1.9 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 GAN04527.1 - 0.0089 15.0 0.3 0.44 9.5 0.1 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GAN04527.1 - 0.014 15.0 0.4 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAN04527.1 - 0.017 15.0 0.1 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 GAN04527.1 - 0.1 12.5 0.1 11 5.9 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 GAN04527.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 GAN04528.1 - 1.9e-32 110.7 14.3 5e-07 30.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04528.1 - 1.8e-07 31.4 0.3 0.017 15.4 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1921 PF09081.10 GAN04528.1 - 0.0022 18.2 0.0 0.51 10.6 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1921) Methyltransf_25 PF13649.6 GAN04529.1 - 1.7e-12 47.9 0.0 4.8e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN04529.1 - 1.5e-11 44.8 0.0 3.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN04529.1 - 1.1e-08 35.1 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN04529.1 - 2.2e-06 27.5 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN04529.1 - 0.0058 16.1 0.0 0.032 13.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 GAN04529.1 - 0.0073 15.7 0.0 0.033 13.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN04529.1 - 0.0079 16.9 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN04529.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain zf-met PF12874.7 GAN04531.1 - 3.7e-14 52.6 77.0 0.00064 20.0 1.0 10.3 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN04531.1 - 3.9e-11 42.8 102.9 0.025 15.4 2.8 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN04531.1 - 2.6e-09 37.1 68.5 0.0023 18.2 0.2 9.8 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAN04531.1 - 1.9e-07 31.2 106.5 0.0074 16.7 3.1 10.4 10 0 0 10 10 10 7 Zinc finger, C2H2 type DUF629 PF04780.12 GAN04531.1 - 0.017 13.7 55.3 0.3 9.5 0.1 8.9 6 3 3 9 9 9 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 GAN04531.1 - 0.037 13.7 0.3 0.037 13.7 0.3 8.2 9 0 0 9 9 9 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 GAN04531.1 - 0.058 13.7 64.5 0.085 13.2 3.9 8.9 2 2 6 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 GAN04531.1 - 0.38 11.4 31.3 0.26 12.0 1.3 6.0 4 2 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats C1_2 PF03107.16 GAN04531.1 - 1.4 9.3 47.2 0.79 10.1 0.4 10.0 9 1 1 10 10 10 0 C1 domain TPP_enzyme_N PF02776.18 GAN04532.1 - 3.4e-29 101.6 0.0 6.3e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAN04532.1 - 3.4e-17 62.6 0.2 3.6e-15 56.1 0.0 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAN04532.1 - 1.3e-16 60.6 0.0 2.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF362 PF04015.12 GAN04532.1 - 0.0002 21.7 0.0 0.00062 20.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF362) Steroid_dh PF02544.16 GAN04533.1 - 1.8e-34 118.9 7.2 4.3e-34 117.7 5.9 2.0 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ubiquitin_5 PF18037.1 GAN04533.1 - 0.042 14.2 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1206 PF06724.11 GAN04534.1 - 3.9e-28 97.3 22.4 1.4e-14 53.9 2.0 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) TNFR_16_TM PF18422.1 GAN04534.1 - 0.017 15.1 1.4 0.017 15.1 1.4 1.9 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4307 PF14155.6 GAN04534.1 - 0.17 11.7 1.3 4.6 7.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF373 PF04123.13 GAN04534.1 - 2.6 7.4 5.1 16 4.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Aminotran_1_2 PF00155.21 GAN04535.1 - 4.6e-41 141.2 0.0 5.8e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAN04535.1 - 0.059 11.9 0.0 0.087 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Not3 PF04065.15 GAN04536.1 - 2.4e-88 295.4 29.8 4.1e-88 294.7 29.8 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GAN04536.1 - 7.4e-45 152.2 12.9 7.4e-45 152.2 12.9 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family SesA PF17107.5 GAN04536.1 - 0.088 13.0 0.4 0.088 13.0 0.4 3.0 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DHO_dh PF01180.21 GAN04536.1 - 0.28 10.4 0.5 0.42 9.8 0.5 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase H-kinase_dim PF02895.14 GAN04536.1 - 3.1 8.3 5.3 0.62 10.5 0.5 2.4 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Aldo_ket_red PF00248.21 GAN04538.1 - 2.4e-31 109.1 0.0 2.8e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_P_Rpp14 PF01900.19 GAN04539.1 - 5e-20 71.7 0.0 6.4e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RicinB_lectin_2 PF14200.6 GAN04540.1 - 0.00048 20.8 0.0 0.013 16.2 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN04540.1 - 0.0093 16.2 0.8 0.043 14.1 0.7 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain zf-RING_2 PF13639.6 GAN04541.1 - 2e-14 53.6 5.8 3.8e-14 52.7 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN04541.1 - 1.3e-11 44.0 1.9 1.3e-11 44.0 1.9 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAN04541.1 - 2.9e-09 36.6 5.4 5.7e-09 35.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN04541.1 - 3.8e-09 36.2 6.3 6.7e-09 35.4 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 GAN04541.1 - 5.1e-08 32.8 0.0 9.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 GAN04541.1 - 8.3e-06 26.0 9.7 5.6e-05 23.4 9.7 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN04541.1 - 2.7e-05 24.0 5.1 4.7e-05 23.3 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAN04541.1 - 0.00032 20.6 0.9 0.00032 20.6 0.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAN04541.1 - 0.0012 18.8 3.3 0.0031 17.5 3.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAN04541.1 - 0.0049 16.7 7.1 0.0083 16.0 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2681 PF10883.8 GAN04541.1 - 0.0055 17.1 5.6 0.053 13.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) Prok-RING_4 PF14447.6 GAN04541.1 - 0.0074 16.1 7.3 0.015 15.1 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PHD PF00628.29 GAN04541.1 - 0.069 13.1 5.5 0.16 11.9 5.5 1.7 1 0 0 1 1 1 0 PHD-finger DUF2339 PF10101.9 GAN04541.1 - 0.079 11.5 0.1 0.094 11.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Tom22 PF04281.13 GAN04541.1 - 0.1 12.4 0.4 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 zf-RING_4 PF14570.6 GAN04541.1 - 0.16 11.8 5.1 0.31 10.9 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 GAN04541.1 - 0.17 12.3 4.7 0.32 11.3 4.7 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 GAN04541.1 - 0.19 11.4 7.6 0.38 10.4 7.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 GAN04541.1 - 0.29 11.3 3.7 0.89 9.8 3.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 GAN04541.1 - 0.36 11.0 7.2 1.6 8.9 7.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 GAN04541.1 - 2.9 8.1 9.6 0.13 12.4 3.2 2.2 3 1 0 3 3 1 0 RING-variant domain Sds3 PF08598.11 GAN04542.1 - 2.3e-19 70.3 14.4 4.3e-19 69.4 14.4 1.4 1 0 0 1 1 1 1 Sds3-like PspB PF06667.12 GAN04543.1 - 0.029 14.4 1.2 3.4 7.8 0.1 2.3 2 0 0 2 2 2 0 Phage shock protein B Pal1 PF08316.11 GAN04543.1 - 0.056 14.2 0.2 18 6.1 0.0 2.2 2 0 0 2 2 2 0 Pal1 cell morphology protein EB PF01683.18 GAN04543.1 - 0.22 11.9 25.2 1.1 9.6 9.5 3.3 2 2 1 3 3 3 0 EB module LEAP-2 PF07359.11 GAN04543.1 - 2.1 8.2 6.3 1.4 8.8 0.9 2.5 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Dickkopf_N PF04706.12 GAN04543.1 - 2.6 8.6 25.4 3.5 8.2 8.2 2.7 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Trypan_PARP PF05887.11 GAN04544.1 - 0.14 12.2 25.6 0.21 11.5 25.6 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1206 PF06724.11 GAN04546.1 - 4.7e-08 33.0 1.9 4.7e-08 33.0 1.9 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1206) GDA1_CD39 PF01150.17 GAN04546.1 - 0.099 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DUF1206 PF06724.11 GAN04547.1 - 0.00083 19.4 0.3 0.0015 18.5 0.3 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) P_C PF06640.11 GAN04547.1 - 0.032 14.4 0.1 0.039 14.1 0.1 1.1 1 0 0 1 1 1 0 P protein C-terminus Ehbp PF10622.9 GAN04547.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) Pkinase PF00069.25 GAN04548.1 - 2e-41 142.1 0.2 3.1e-41 141.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04548.1 - 3.8e-34 118.1 0.1 6.4e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04548.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN04548.1 - 0.054 13.4 0.1 0.45 10.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN04548.1 - 0.075 12.0 0.3 0.17 10.8 0.3 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAN04548.1 - 0.19 11.0 0.1 0.32 10.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HbrB PF08539.11 GAN04549.1 - 7.8e-38 130.1 0.2 5e-36 124.2 0.2 3.2 1 1 0 1 1 1 1 HbrB-like CCD48 PF15799.5 GAN04549.1 - 0.043 12.1 0.1 0.07 11.4 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 SRF-TF PF00319.18 GAN04550.1 - 2e-21 75.2 0.2 2.8e-21 74.7 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MBOAT PF03062.19 GAN04551.1 - 3.2e-40 138.6 20.7 5.2e-40 137.9 20.7 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PsaL PF02605.15 GAN04551.1 - 0.1 12.3 0.4 0.82 9.3 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Peroxidase_2 PF01328.17 GAN04552.1 - 3.3e-38 132.1 0.0 4.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PDZ_1 PF12812.7 GAN04553.1 - 2.5e-43 146.0 0.0 7.2e-31 106.0 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 GAN04553.1 - 1.1e-23 84.8 0.7 1.6e-17 64.8 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 GAN04553.1 - 4.8e-13 49.2 0.3 4.9e-06 26.8 0.0 4.3 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 GAN04553.1 - 1.2e-12 47.4 0.0 8e-05 22.4 0.0 3.9 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 GAN04553.1 - 1.2e-09 38.4 0.0 0.00011 22.4 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 GAN04553.1 - 0.024 14.6 0.4 0.24 11.4 0.0 2.8 3 0 0 3 3 3 0 Tricorn protease PDZ domain DUF31 PF01732.16 GAN04553.1 - 0.09 12.3 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 GAN04553.1 - 0.24 10.0 0.4 0.51 8.9 0.1 1.6 2 0 0 2 2 2 0 Peptidase S46 Hist_deacetyl PF00850.19 GAN04554.1 - 8.6e-83 278.3 0.0 1.3e-82 277.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF2129 PF09902.9 GAN04554.1 - 0.18 11.9 1.0 5.3 7.2 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) CDC27 PF09507.10 GAN04555.1 - 3.2e-26 92.7 27.8 1.4e-13 51.1 13.9 2.2 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Dicty_REP PF05086.12 GAN04555.1 - 9.7 4.0 14.1 16 3.3 14.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NAD_kinase PF01513.21 GAN04556.1 - 5.7e-66 222.7 0.0 6e-65 219.3 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase tRNA-synt_1b PF00579.25 GAN04557.1 - 4.9e-71 239.4 0.0 7.5e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S28e PF01200.18 GAN04558.1 - 1.1e-33 115.0 1.3 1.2e-33 114.9 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 GAN04558.1 - 0.037 14.4 0.0 0.039 14.3 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Sds3 PF08598.11 GAN04559.1 - 9.3e-21 74.8 2.1 9.3e-21 74.8 2.1 3.7 2 1 0 2 2 2 1 Sds3-like Pkinase PF00069.25 GAN04561.1 - 1.8e-55 188.2 0.0 1.3e-36 126.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04561.1 - 3.2e-25 88.9 0.0 5.1e-25 88.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04561.1 - 1.8e-07 30.8 0.1 2e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAN04561.1 - 8.2e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAN04561.1 - 0.0025 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAN04561.1 - 0.042 12.8 0.7 0.064 12.2 0.2 1.5 2 0 0 2 2 2 0 Haspin like kinase domain DUF3153 PF11353.8 GAN04561.1 - 0.051 13.1 0.0 2.3 7.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3153) APH PF01636.23 GAN04561.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN04561.1 - 0.073 11.8 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAG PF15347.6 GAN04562.1 - 0.013 14.6 17.6 0.021 13.8 17.6 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Adeno_E3_CR2 PF02439.15 GAN04562.1 - 4 7.3 6.5 8.6 6.2 6.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HAGH_C PF16123.5 GAN04563.1 - 1.4e-24 86.4 0.2 2e-24 85.9 0.2 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAN04563.1 - 1.1e-09 38.7 6.0 6.7e-08 32.8 6.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN04563.1 - 0.00034 20.2 0.5 0.0049 16.4 0.5 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NDUF_B8 PF05821.11 GAN04564.1 - 2.4e-10 40.6 0.5 7.9e-10 38.9 0.5 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Lum_binding PF00677.17 GAN04565.1 - 2e-46 155.9 3.2 1.4e-22 79.5 0.6 2.1 2 0 0 2 2 2 2 Lumazine binding domain MFS_1 PF07690.16 GAN04566.1 - 1.4e-53 182.1 23.2 4.1e-33 114.8 3.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN04566.1 - 3.2e-13 49.0 14.7 4.6e-08 32.0 3.7 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 GAN04566.1 - 1.5e-11 43.8 13.6 1e-10 41.1 13.3 2.8 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 GAN04566.1 - 1.5e-11 43.8 18.5 9.5e-11 41.2 18.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 GAN04566.1 - 0.054 11.8 7.1 0.2 9.9 0.2 3.6 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.17 GAN04566.1 - 0.065 12.3 2.0 0.091 11.8 0.1 2.0 2 0 0 2 2 2 0 CLN3 protein DUF3487 PF11990.8 GAN04566.1 - 0.92 9.4 0.0 0.92 9.4 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3487) LacY_symp PF01306.19 GAN04566.1 - 1.1 8.0 12.8 2.3 6.9 3.4 3.9 2 2 1 3 3 3 0 LacY proton/sugar symporter F-box PF00646.33 GAN04567.1 - 6.5e-09 35.4 1.4 2.1e-08 33.8 1.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN04567.1 - 2.4e-08 33.7 1.0 1.2e-07 31.5 0.8 2.2 2 0 0 2 2 2 1 F-box-like FBD PF08387.10 GAN04567.1 - 0.0024 17.7 0.0 0.04 13.8 0.1 2.9 2 1 0 2 2 2 1 FBD F-box_4 PF15966.5 GAN04567.1 - 0.018 14.9 0.3 0.051 13.5 0.3 1.9 1 0 0 1 1 1 0 F-box LRR_5 PF13306.6 GAN04567.1 - 0.036 14.0 0.3 0.24 11.4 0.0 2.2 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Lipase_GDSL PF00657.22 GAN04568.1 - 1.3e-08 35.1 0.5 1.5e-08 34.8 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN04568.1 - 2.1e-08 34.8 0.3 3.4e-08 34.1 0.3 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.18 GAN04569.1 - 2.6e-38 131.6 0.2 2.6e-38 131.6 0.2 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN04569.1 - 8.5e-10 38.6 10.9 2.2e-09 37.3 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NtA PF03146.15 GAN04569.1 - 0.11 12.4 0.1 18 5.3 0.0 2.4 2 0 0 2 2 2 0 Agrin NtA domain Myosin_head PF00063.21 GAN04570.1 - 2.2e-266 885.5 0.9 3.6e-266 884.7 0.9 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 GAN04570.1 - 2.7e-28 98.3 2.2 1.3e-27 96.0 2.2 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 GAN04570.1 - 5.6e-19 66.1 31.4 9.7e-07 28.1 0.8 7.5 7 0 0 7 7 7 5 IQ calmodulin-binding motif AAA_22 PF13401.6 GAN04570.1 - 0.024 14.9 0.4 0.099 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fez1 PF06818.15 GAN04570.1 - 0.16 12.4 22.6 0.11 13.0 20.3 2.0 1 1 0 1 1 1 0 Fez1 AAA_16 PF13191.6 GAN04570.1 - 0.25 11.7 0.0 0.25 11.7 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain APG6_N PF17675.1 GAN04570.1 - 0.4 11.2 27.9 0.12 12.9 22.4 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 GAN04570.1 - 0.7 10.6 12.4 0.2 12.4 3.7 3.2 1 1 0 2 2 2 0 Occludin homology domain TolA_bind_tri PF16331.5 GAN04570.1 - 0.91 9.7 8.3 2.2 8.4 3.1 3.6 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4349 PF14257.6 GAN04570.1 - 1.1 8.7 8.5 2.1 7.7 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LMBR1 PF04791.16 GAN04570.1 - 3.6 6.4 10.1 7.8 5.3 10.1 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein CCDC-167 PF15188.6 GAN04570.1 - 6.8 7.1 13.2 11 6.5 7.5 3.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 ABC_tran PF00005.27 GAN04570.1 - 8.3 6.9 7.8 1.1 9.8 0.0 3.2 2 1 0 2 2 1 0 ABC transporter YxiJ PF14176.6 GAN04572.1 - 0.012 16.1 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 YxiJ-like protein SUKH_6 PF14568.6 GAN04572.1 - 0.039 14.4 0.0 0.18 12.3 0.0 2.2 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 GAN04572.1 - 0.065 13.0 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 GAN04572.1 - 0.078 13.4 0.0 0.31 11.4 0.0 2.1 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) DUF4448 PF14610.6 GAN04572.1 - 0.29 10.9 3.4 0.43 10.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) MAP17 PF15807.5 GAN04572.1 - 0.35 11.1 2.1 2.2 8.5 0.2 3.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RRM_1 PF00076.22 GAN04573.1 - 4.5e-57 189.8 0.3 3.3e-17 62.0 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN04573.1 - 1.7e-06 28.1 0.1 1.2 9.3 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif RRM_5 PF13893.6 GAN04573.1 - 0.00064 19.3 0.0 1.3 8.6 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN04573.1 - 0.0012 18.6 0.0 1.9 8.4 0.0 3.9 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 GAN04573.1 - 0.0013 18.7 4.8 5.6 7.1 0.1 4.2 3 1 0 3 3 3 2 RNA binding motif RRM_Rrp7 PF17799.1 GAN04573.1 - 0.0037 17.1 0.1 4.5 7.0 0.0 3.3 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain Nop14 PF04147.12 GAN04573.1 - 0.11 10.7 32.4 0.25 9.5 32.4 1.5 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 GAN04573.1 - 0.12 12.4 23.4 0.0098 15.9 18.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nup35_RRM_2 PF14605.6 GAN04573.1 - 0.15 12.1 0.0 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 GAN04573.1 - 0.18 11.8 0.0 13 5.9 0.0 2.9 2 1 0 2 2 2 0 RNA binding domain DUF778 PF05608.12 GAN04573.1 - 1.7 9.0 3.6 0.94 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF778) Oxidored_FMN PF00724.20 GAN04574.1 - 2.2e-98 329.7 0.0 2.7e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 GAN04574.1 - 0.09 12.5 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) DHHC PF01529.20 GAN04576.1 - 9.9e-28 96.9 14.8 1.6e-27 96.2 6.3 2.6 2 1 0 2 2 2 2 DHHC palmitoyltransferase RhoGAP PF00620.27 GAN04577.1 - 4e-37 127.4 0.0 1.1e-36 126.0 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain QCR10 PF09796.9 GAN04578.1 - 1.8e-17 63.2 0.1 1.9e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_hydro_16 PF00722.21 GAN04579.1 - 1.7e-37 128.6 1.4 2.5e-37 128.1 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DEAD PF00270.29 GAN04580.1 - 1.8e-47 161.4 0.0 3.1e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN04580.1 - 5.4e-30 104.0 0.0 1.9e-29 102.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN04580.1 - 2.7e-05 24.2 0.0 5.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAN04580.1 - 0.049 12.4 0.0 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HdeA PF06411.11 GAN04580.1 - 0.16 12.1 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 HdeA/HdeB family Aa_trans PF01490.18 GAN04581.1 - 1.8e-60 204.8 33.8 2e-60 204.6 33.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 GAN04582.1 - 1.4e-59 201.8 38.4 1.8e-59 201.5 38.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 GAN04582.1 - 4e-07 29.2 21.2 4e-07 29.2 21.2 2.4 1 1 1 2 2 2 1 Spore germination protein AA_permease_2 PF13520.6 GAN04582.1 - 4.7e-07 29.0 47.6 6.9e-07 28.4 47.6 1.1 1 0 0 1 1 1 1 Amino acid permease 7TMR-DISM_7TM PF07695.11 GAN04582.1 - 0.01 15.8 11.7 0.01 15.8 11.7 3.3 2 1 0 3 3 3 1 7TM diverse intracellular signalling UPF0139 PF03669.13 GAN04582.1 - 0.28 11.1 0.0 0.28 11.1 0.0 3.3 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0139) Collectrin PF16959.5 GAN04582.1 - 1 9.1 3.8 3.4 7.4 3.8 2.0 1 0 0 1 1 1 0 Renal amino acid transporter Aa_trans PF01490.18 GAN04583.1 - 3.7e-64 216.9 32.2 4.3e-64 216.7 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peroxin-22 PF12827.7 GAN04584.1 - 0.0069 16.3 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family KptA_kDCL PF18176.1 GAN04584.1 - 0.026 14.4 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain DUF4596 PF15363.6 GAN04584.1 - 6.6 7.0 6.1 14 6.0 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) SIR2 PF02146.17 GAN04585.1 - 2.8e-38 131.6 0.0 4.1e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAN04585.1 - 0.003 17.3 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain K_oxygenase PF13434.6 GAN04585.1 - 0.094 11.8 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-CCCH_2 PF14608.6 GAN04586.1 - 2e-07 31.2 20.7 4.5e-05 23.8 1.1 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Flag1_repress PF03614.13 GAN04586.1 - 0.065 13.0 4.0 0.029 14.2 0.9 2.0 2 0 0 2 2 2 0 Repressor of phase-1 flagellin zf-CCCH PF00642.24 GAN04586.1 - 0.092 12.7 7.2 1.2 9.2 3.8 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Disintegrin PF00200.23 GAN04586.1 - 0.3 11.9 4.5 0.86 10.4 4.5 1.7 1 0 0 1 1 1 0 Disintegrin zf_CCCH_4 PF18345.1 GAN04586.1 - 0.34 11.0 8.1 21 5.3 7.9 2.7 1 1 1 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 GAN04586.1 - 3.4 7.6 11.7 19 5.2 10.7 2.4 1 1 1 2 2 2 0 CCCH-type zinc finger Cyclin_N PF00134.23 GAN04587.1 - 5.3e-07 29.4 0.1 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN04587.1 - 9.6e-06 26.1 1.4 4.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin DUF1635 PF07795.11 GAN04587.1 - 0.0094 15.8 1.8 0.017 15.0 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) zf-C2H2_8 PF15909.5 GAN04587.1 - 0.021 15.1 0.5 0.059 13.7 0.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon GATA PF00320.27 GAN04588.1 - 3.5e-16 58.5 7.2 6.2e-16 57.7 7.2 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 GAN04588.1 - 2.6e-14 53.3 0.0 5.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GAN04588.1 - 1.9e-10 40.8 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAN04588.1 - 7.3e-08 32.6 0.0 2.3e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 PAS domain PAS_11 PF14598.6 GAN04588.1 - 6.6e-07 29.4 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 GAN04588.1 - 0.003 17.6 0.3 0.0061 16.6 0.3 1.5 1 0 0 1 1 1 1 Zinc ribbon domain PAS_4 PF08448.10 GAN04588.1 - 0.0037 17.5 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold CCDC106 PF15794.5 GAN04588.1 - 0.0062 16.3 3.3 0.0062 16.3 3.3 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 106 DZR PF12773.7 GAN04588.1 - 0.064 13.3 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Rubredoxin_2 PF18073.1 GAN04588.1 - 0.36 10.6 1.5 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Nudix_N_2 PF14803.6 GAN04588.1 - 0.41 10.6 2.1 0.85 9.6 2.1 1.5 1 0 0 1 1 1 0 Nudix N-terminal CENP-M PF11111.8 GAN04589.1 - 4.8e-10 38.9 0.5 6.7e-10 38.4 0.5 1.1 1 0 0 1 1 1 1 Centromere protein M (CENP-M) DICT PF10069.9 GAN04589.1 - 0.00095 18.9 0.3 0.0014 18.4 0.3 1.3 1 0 0 1 1 1 1 Sensory domain in DIguanylate Cyclases and Two-component system PduV-EutP PF10662.9 GAN04589.1 - 0.011 15.5 0.1 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SNF2_N PF00176.23 GAN04590.1 - 2.2e-72 243.7 1.0 2.2e-72 243.7 1.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN04590.1 - 1.2e-19 70.6 1.0 2.3e-18 66.5 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 GAN04590.1 - 1.1e-18 67.3 8.2 1.1e-18 67.3 8.2 3.7 3 0 0 3 3 3 1 HSA SnAC PF14619.6 GAN04590.1 - 5e-14 52.7 6.9 5e-14 52.7 6.9 3.5 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 GAN04590.1 - 1.2e-09 38.4 1.4 4.2e-09 36.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 GAN04590.1 - 0.077 13.0 1.7 0.32 11.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF3439 PF11921.8 GAN04590.1 - 0.12 12.3 10.5 0.35 10.8 10.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SR-25 PF10500.9 GAN04591.1 - 0.004 16.8 6.2 0.004 16.8 6.2 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 GAN04591.1 - 0.27 10.9 4.4 0.43 10.3 4.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IMUP PF15761.5 GAN04591.1 - 2.9 8.6 18.9 0.15 12.8 9.7 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Drf_GBD PF06371.13 GAN04592.1 - 4.8e-15 55.6 0.0 2e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain DUF3290 PF11694.8 GAN04593.1 - 1.4 8.9 4.4 1.6 8.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Hepcidin PF06446.12 GAN04593.1 - 1.4 9.4 9.3 0.33 11.4 3.7 2.1 2 0 0 2 2 2 0 Hepcidin KH_1 PF00013.29 GAN04594.1 - 1.9e-29 101.2 0.0 1.1e-07 31.6 0.0 7.0 8 0 0 8 8 8 5 KH domain ArsA_ATPase PF02374.15 GAN04595.1 - 3.8e-114 381.0 1.7 4.4e-114 380.8 1.7 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 GAN04595.1 - 9.7e-14 51.7 0.1 3.2e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 GAN04595.1 - 1.3e-11 44.6 0.0 2.3e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GAN04595.1 - 4.4e-06 26.3 0.6 7.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 GAN04595.1 - 5.3e-06 26.1 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 GAN04595.1 - 3.6e-05 23.4 0.0 7.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 GAN04595.1 - 0.00012 21.7 1.4 0.00077 19.1 0.1 2.5 2 1 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 GAN04595.1 - 0.0033 17.0 0.0 0.013 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAN04595.1 - 0.0037 17.0 0.0 0.016 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAN04595.1 - 0.026 13.7 0.1 0.064 12.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 GAN04595.1 - 0.055 12.9 0.0 0.21 11.0 0.0 2.0 3 0 0 3 3 3 0 PhoH-like protein Zeta_toxin PF06414.12 GAN04595.1 - 0.09 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF5131 PF07505.11 GAN04595.1 - 0.11 12.0 0.0 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF5131) AAA_18 PF13238.6 GAN04595.1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DnaJ_C PF01556.18 GAN04596.1 - 3.7e-40 137.4 0.0 6.3e-40 136.7 0.0 1.4 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN04596.1 - 1.1e-26 92.7 1.6 1.7e-26 92.1 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAN04596.1 - 1.2e-15 57.6 18.9 1.9e-15 56.9 18.9 1.3 1 0 0 1 1 1 1 DnaJ central domain AtuA PF07287.11 GAN04597.1 - 9.6e-114 379.7 0.0 1.2e-113 379.4 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Ricin_B_lectin PF00652.22 GAN04598.1 - 1.4e-05 25.3 0.4 0.078 13.2 0.3 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain DUF1651 PF07864.11 GAN04598.1 - 0.026 14.8 0.1 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) RicinB_lectin_2 PF14200.6 GAN04598.1 - 0.083 13.6 3.1 0.9 10.3 0.1 3.0 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like DUF4793 PF16041.5 GAN04598.1 - 0.14 12.4 1.0 67 3.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4793) Ribosomal_S16 PF00886.19 GAN04599.1 - 7.8e-28 96.3 0.1 1e-27 96.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Na_sulph_symp PF00939.19 GAN04601.1 - 1.9e-34 119.6 29.8 2.6e-34 119.1 29.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN04601.1 - 1.8e-26 93.1 43.4 1.7e-20 73.4 22.7 2.4 2 1 1 3 3 3 2 Citrate transporter SPX PF03105.19 GAN04601.1 - 4.4e-23 82.8 15.0 2.3e-21 77.1 14.5 2.9 1 1 0 1 1 1 1 SPX domain DUF4179 PF13786.6 GAN04601.1 - 0.16 12.5 1.0 1.4 9.5 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Acid_PPase PF12689.7 GAN04602.1 - 2.4e-49 167.4 0.0 2.8e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 GAN04602.1 - 0.17 11.7 0.1 1.2 8.9 0.1 2.0 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase SNAP PF14938.6 GAN04603.1 - 1e-91 307.3 18.7 1.6e-91 306.7 18.7 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Arrestin_N PF00339.29 GAN04603.1 - 2.7e-09 37.2 0.0 8.2e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain NSF PF02071.20 GAN04603.1 - 0.00083 19.6 17.7 12 7.2 0.2 7.0 6 0 0 6 6 6 3 Aromatic-di-Alanine (AdAR) repeat TPR_12 PF13424.6 GAN04603.1 - 0.0083 16.4 8.6 0.032 14.5 2.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAN04603.1 - 0.68 9.6 9.7 0.27 10.9 6.8 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain Pkinase PF00069.25 GAN04604.1 - 3.4e-66 223.3 0.0 4.4e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04604.1 - 3.3e-39 134.7 0.0 4.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN04604.1 - 0.00016 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAN04604.1 - 0.0016 18.4 0.0 0.12 12.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN04604.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAN04604.1 - 0.0054 16.1 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN04604.1 - 0.15 11.0 0.1 0.43 9.5 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 GAN04604.1 - 0.24 10.4 0.0 0.49 9.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 GAN04605.1 - 3.9e-60 203.4 0.0 6.4e-39 133.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04605.1 - 1.3e-28 100.0 0.0 2.8e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 GAN04605.1 - 3.2e-15 56.3 2.6 5.8e-15 55.4 0.4 2.5 3 0 0 3 3 3 1 Response regulator receiver domain Kinase-like PF14531.6 GAN04605.1 - 0.0004 19.8 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAN04605.1 - 0.0063 15.5 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAN04605.1 - 0.0072 16.3 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS PF00989.25 GAN04605.1 - 0.04 13.9 0.1 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 PAS fold Seadorna_VP7 PF07387.11 GAN04605.1 - 0.056 12.5 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.7 GAN04605.1 - 0.07 13.4 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 PAS domain WD40 PF00400.32 GAN04608.1 - 4.3e-12 46.3 3.7 0.0012 19.7 0.1 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04608.1 - 0.00016 21.9 0.0 0.45 10.8 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN04608.1 - 0.0015 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 GAN04608.1 - 0.012 15.5 0.0 0.7 9.9 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Macoilin PF09726.9 GAN04608.1 - 0.38 9.3 11.5 0.57 8.7 11.5 1.1 1 0 0 1 1 1 0 Macoilin family Thionin PF00321.17 GAN04609.1 - 0.016 15.7 1.5 0.31 11.5 0.5 2.4 2 0 0 2 2 2 0 Plant thionin Rab3-GTPase_cat PF13890.6 GAN04609.1 - 0.029 14.0 0.1 0.081 12.6 0.1 1.8 1 1 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Kelch_5 PF13854.6 GAN04610.1 - 1.1e-15 57.2 0.2 1.2e-05 25.2 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 GAN04610.1 - 1.1e-12 47.7 1.8 8.3e-05 22.7 0.0 3.9 2 1 1 3 3 3 3 Kelch motif Kelch_3 PF13415.6 GAN04610.1 - 6e-12 45.5 10.4 1.4e-08 34.8 0.0 5.7 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN04610.1 - 5.5e-11 42.0 1.4 0.00031 20.6 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 GAN04610.1 - 1.8e-09 37.0 0.6 0.01 15.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 GAN04610.1 - 5e-08 33.2 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 GAN04610.1 - 8.4e-08 32.1 3.9 0.0038 17.2 0.0 4.5 4 1 0 4 4 4 3 Galactose oxidase, central domain MRI PF15325.6 GAN04610.1 - 0.16 13.1 1.1 0.34 12.0 1.1 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection NAPRTase_C PF17956.1 GAN04610.1 - 0.51 10.8 2.9 6.8 7.2 1.0 2.7 1 1 1 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain MMR_HSR1 PF01926.23 GAN04611.1 - 1.7e-18 66.7 1.5 3.2e-14 53.0 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN04611.1 - 1.2e-09 37.9 0.7 3e-06 26.9 0.1 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAN04611.1 - 4.5e-06 26.7 2.8 0.0091 15.9 0.2 2.8 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAN04611.1 - 1.8e-05 24.4 3.9 6.1e-05 22.7 0.1 3.2 3 2 0 4 4 4 1 Elongation factor Tu GTP binding domain cobW PF02492.19 GAN04611.1 - 0.022 14.3 1.0 0.12 11.9 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 GAN04611.1 - 0.066 13.3 0.7 0.066 13.3 0.7 4.2 3 2 1 4 4 4 0 Dynamin family UPF0767 PF15990.5 GAN04611.1 - 0.1 12.7 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 UPF0767 family GN3L_Grn1 PF08701.11 GAN04611.1 - 0.42 10.8 18.5 0.35 11.0 11.5 2.5 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase AAA_18 PF13238.6 GAN04611.1 - 0.59 10.7 0.0 0.59 10.7 0.0 2.8 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 GAN04611.1 - 0.94 9.7 7.4 12 6.1 0.1 3.7 2 1 2 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase EVI2A PF05399.11 GAN04612.1 - 0.11 12.1 4.7 0.13 11.9 4.7 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DSS1_SEM1 PF05160.13 GAN04613.1 - 8.1e-22 77.1 23.6 8.1e-22 77.1 23.6 1.8 1 1 1 2 2 2 1 DSS1/SEM1 family DUF2947 PF11163.8 GAN04613.1 - 0.063 13.1 11.2 0.08 12.8 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Cwf_Cwc_15 PF04889.12 GAN04613.1 - 0.36 10.5 16.3 0.4 10.4 16.3 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein F-box-like PF12937.7 GAN04614.1 - 1.4e-07 31.2 0.0 3.8e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like ACP_PD PF04336.12 GAN04614.1 - 0.088 13.2 0.2 0.45 10.9 0.2 2.3 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase LBP_C PF17386.2 GAN04615.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain Zn_clus PF00172.18 GAN04616.1 - 0.0006 19.9 18.1 0.0011 19.0 18.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 GAN04616.1 - 0.084 13.0 6.2 13 5.9 2.8 3.4 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Lin-8 PF03353.15 GAN04617.1 - 1.4 8.4 13.1 2 7.9 13.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIEZO PF15917.5 GAN04617.1 - 1.7 8.1 11.9 1.5 8.3 10.8 1.3 1 1 0 1 1 1 0 Piezo Roughex PF06020.11 GAN04617.1 - 2.9 6.9 5.4 3.8 6.5 5.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PAT1 PF09770.9 GAN04617.1 - 5 5.3 17.6 5.9 5.0 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 P5-ATPase PF12409.8 GAN04617.1 - 5.5 7.1 5.8 2.7 8.1 3.7 1.5 2 0 0 2 2 2 0 P5-type ATPase cation transporter RINGv PF12906.7 GAN04618.1 - 1.8e-13 50.4 3.2 3.9e-13 49.3 3.2 1.5 1 0 0 1 1 1 1 RING-variant domain DUF1345 PF07077.11 GAN04618.1 - 0.02 14.6 0.3 0.02 14.6 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) zf-RING_2 PF13639.6 GAN04618.1 - 0.18 12.2 5.4 0.34 11.3 5.4 1.4 1 0 0 1 1 1 0 Ring finger domain Homeodomain PF00046.29 GAN04619.1 - 2.1e-17 62.7 2.8 4.6e-17 61.6 2.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN04619.1 - 0.015 15.2 1.6 0.02 14.8 0.3 1.9 2 0 0 2 2 2 0 Homeobox KN domain GH-E PF14410.6 GAN04619.1 - 0.059 13.8 1.4 9.4 6.7 0.2 2.7 1 1 1 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues PRMT5_TIM PF17285.2 GAN04620.1 - 8.9e-62 208.6 0.6 1.2e-61 208.2 0.6 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GAN04620.1 - 1.3e-59 201.0 0.0 2.9e-59 199.8 0.0 1.7 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GAN04620.1 - 3.3e-54 183.4 0.9 5.3e-54 182.8 0.9 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Sulfate_transp PF00916.20 GAN04623.1 - 3e-106 355.4 23.7 4.3e-106 354.9 23.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN04623.1 - 3.5e-09 36.3 0.0 6.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN04623.1 - 0.0024 18.3 1.9 0.0024 18.3 1.9 3.0 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 GAN04623.1 - 0.011 16.0 0.1 0.027 14.8 0.1 1.6 1 0 0 1 1 1 0 STAS domain Gly-rich_Ago1 PF12764.7 GAN04623.1 - 0.11 13.4 1.5 0.37 11.6 1.4 1.9 2 0 0 2 2 2 0 Glycine-rich region of argonaut SpoIIIAC PF06686.11 GAN04623.1 - 2.7 8.2 8.4 0.43 10.8 1.4 2.9 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family G-patch_2 PF12656.7 GAN04624.1 - 5.7e-22 77.6 0.4 2.4e-21 75.6 0.4 2.2 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 GAN04624.1 - 0.0015 18.4 0.1 0.0044 16.9 0.1 1.8 1 0 0 1 1 1 1 G-patch domain Utp11 PF03998.13 GAN04624.1 - 4.4 7.2 8.9 6.4 6.6 3.8 2.1 1 1 1 2 2 2 0 Utp11 protein 4HBT PF03061.22 GAN04625.1 - 0.0016 18.8 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily Glyco_hydro_2_C PF02836.17 GAN04625.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain C2 PF00168.30 GAN04626.1 - 2.7e-22 79.0 1.7 6.3e-10 39.3 0.4 3.1 3 0 0 3 3 3 2 C2 domain Pyr_redox_2 PF07992.14 GAN04627.1 - 9e-21 74.4 0.2 1.3e-13 50.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN04627.1 - 0.00042 19.1 0.0 0.0061 15.3 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 GAN04627.1 - 0.00082 19.4 0.1 2.5 8.1 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAN04627.1 - 0.0015 19.1 0.8 0.17 12.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAN04627.1 - 0.0031 16.8 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 GAN04627.1 - 0.012 14.9 0.9 3.1 7.0 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN04627.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAN04627.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GCV_H PF01597.19 GAN04629.1 - 2.3e-46 156.6 0.6 2.8e-46 156.4 0.6 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 GAN04629.1 - 0.00019 21.2 0.8 0.0011 18.7 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 GAN04629.1 - 0.00033 20.6 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Peptidase_C2 PF00648.21 GAN04630.1 - 9.5e-46 156.2 0.0 1.7e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 GAN04630.1 - 3.7e-18 66.1 0.1 6.5e-06 26.5 0.2 4.9 3 1 0 3 3 3 3 Calpain large subunit, domain III MIT PF04212.18 GAN04630.1 - 1.2e-16 60.6 14.0 7.3e-09 35.6 1.4 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 GAN04630.1 - 0.0055 17.0 3.7 0.21 11.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Rota_NSP3 PF01665.16 GAN04630.1 - 0.0063 15.7 1.2 0.012 14.8 1.2 1.4 1 0 0 1 1 1 1 Rotavirus non-structural protein NSP3 TPR_1 PF00515.28 GAN04630.1 - 0.64 9.9 7.1 1.8 8.5 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN04630.1 - 0.96 9.7 10.3 0.94 9.7 0.2 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat Ribophorin_II PF05817.14 GAN04631.1 - 1.9e-33 115.9 0.1 3.6e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II bZIP_1 PF00170.21 GAN04631.1 - 5.8e-09 35.9 13.9 5.8e-09 35.9 13.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAN04631.1 - 4e-05 23.6 15.1 4e-05 23.6 15.1 3.1 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAN04631.1 - 0.00022 21.7 7.7 0.00022 21.7 7.7 2.8 3 0 0 3 3 3 1 bZIP Maf transcription factor DUF2353 PF09789.9 GAN04631.1 - 0.00035 20.0 2.3 0.00035 20.0 2.3 2.0 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) SAC3 PF12209.8 GAN04631.1 - 1.7 8.9 4.4 21 5.4 0.3 2.5 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain YabA PF06156.13 GAN04631.1 - 1.7 9.3 10.6 0.094 13.4 0.6 3.2 3 0 0 3 3 3 0 Initiation control protein YabA LicD PF04991.13 GAN04631.1 - 2.5 8.2 6.6 0.45 10.6 2.1 2.0 2 1 0 2 2 2 0 LicD family DUF2570 PF10828.8 GAN04631.1 - 7.3 6.5 11.8 1.3 8.9 0.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PP2C PF00481.21 GAN04632.1 - 3.2e-41 141.7 0.0 3.8e-40 138.2 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAN04632.1 - 0.0042 16.7 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C MCPsignal PF00015.21 GAN04632.1 - 0.023 14.5 0.2 0.056 13.2 0.2 1.6 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 GAN04632.1 - 0.035 14.4 0.8 0.16 12.2 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein SPX PF03105.19 GAN04632.1 - 0.038 13.9 5.1 0.074 13.0 5.1 1.4 1 0 0 1 1 1 0 SPX domain DXP_synthase_N PF13292.6 GAN04632.1 - 0.066 12.4 1.1 0.17 11.0 0.1 2.1 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase LOH1CR12 PF10158.9 GAN04632.1 - 0.13 12.3 1.1 0.54 10.3 0.2 2.4 2 1 0 2 2 2 0 Tumour suppressor protein THOC7 PF05615.13 GAN04632.1 - 0.75 10.1 7.4 2.6 8.3 7.4 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 SlyX PF04102.12 GAN04632.1 - 5.1 7.8 10.1 0.48 11.1 1.0 3.3 3 0 0 3 3 3 0 SlyX Sod_Cu PF00080.20 GAN04633.1 - 4.9e-46 156.4 2.7 5.8e-46 156.2 2.7 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Rhomboid PF01694.22 GAN04634.1 - 2.8e-31 108.5 11.6 5.5e-31 107.6 11.6 1.5 1 0 0 1 1 1 1 Rhomboid family DUF2177 PF09945.9 GAN04634.1 - 3.1 7.9 8.4 0.16 12.0 0.7 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) THEG4 PF15834.5 GAN04635.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Testis highly expressed protein 4 Pkinase PF00069.25 GAN04636.1 - 3.7e-73 246.1 0.0 1.1e-23 83.9 0.1 5.4 4 1 0 4 4 4 4 Protein kinase domain HGTP_anticodon2 PF12745.7 GAN04636.1 - 2.8e-38 132.0 5.5 2.8e-38 132.0 5.5 3.3 3 1 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 GAN04636.1 - 1.7e-34 119.3 0.0 4.1e-13 49.2 0.1 5.1 4 1 0 4 4 4 4 Protein tyrosine kinase RWD PF05773.22 GAN04636.1 - 4.1e-18 65.8 0.1 1.5e-17 63.9 0.1 2.1 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 GAN04636.1 - 4.9e-13 49.0 0.0 1.5e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 GAN04636.1 - 4e-06 26.9 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAN04636.1 - 0.0013 18.3 0.8 0.61 9.7 0.5 2.9 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 HGTP_anticodon PF03129.20 GAN04636.1 - 0.025 14.7 1.8 0.041 14.0 0.0 2.3 2 0 0 2 2 2 0 Anticodon binding domain Peptidase_M13 PF01431.21 GAN04637.1 - 1.7e-50 171.5 0.4 3.1e-50 170.6 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 GAN04637.1 - 9.4e-44 150.6 1.1 9.4e-44 150.6 1.1 1.8 2 0 0 2 2 2 1 Peptidase family M13 Amdase PF17645.1 GAN04637.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Arylmalonate decarboxylase adh_short PF00106.25 GAN04638.1 - 9.7e-31 106.7 0.0 4.3e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAN04638.1 - 9.4e-18 64.6 0.0 1.9e-15 57.1 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN04638.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 GAN04638.1 - 0.056 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 GAN04638.1 - 0.12 11.7 0.3 0.48 9.7 0.0 2.0 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 GAN04638.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RNase_P_p30 PF01876.16 GAN04639.1 - 1.2e-38 132.7 1.5 1.9e-38 132.1 1.5 1.3 1 0 0 1 1 1 1 RNase P subunit p30 PPP4R2 PF09184.11 GAN04639.1 - 4.1e-05 23.3 8.5 5.7e-05 22.8 8.5 1.1 1 0 0 1 1 1 1 PPP4R2 Peptidase_C14 PF00656.22 GAN04639.1 - 0.075 13.0 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Caspase domain DUF4611 PF15387.6 GAN04639.1 - 2.1 8.6 12.9 1.7 8.9 4.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Myc_N PF01056.18 GAN04639.1 - 3.7 7.3 11.9 5.6 6.8 5.3 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Gpr1_Fun34_YaaH PF01184.19 GAN04640.1 - 4.7e-73 245.2 17.9 5.6e-73 245.0 17.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CorA PF01544.18 GAN04640.1 - 0.37 10.1 1.3 0.55 9.5 1.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ENTH PF01417.20 GAN04642.1 - 2.6e-46 156.7 0.9 6e-46 155.6 0.9 1.7 1 0 0 1 1 1 1 ENTH domain Acetyltransf_1 PF00583.25 GAN04642.1 - 3.8e-11 43.2 0.0 7.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN04642.1 - 3.9e-10 39.8 0.0 1.2e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN04642.1 - 9.8e-09 35.5 0.0 1.9e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ANTH PF07651.16 GAN04642.1 - 2e-05 23.7 0.0 3.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ANTH domain Acetyltransf_4 PF13420.7 GAN04642.1 - 6e-05 23.2 0.0 0.00031 20.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain VHS PF00790.19 GAN04642.1 - 0.023 14.6 0.1 0.072 12.9 0.1 1.8 1 0 0 1 1 1 0 VHS domain Cpn60_TCP1 PF00118.24 GAN04643.1 - 3.3e-156 520.8 14.5 3.7e-156 520.6 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcfK PF14058.6 GAN04643.1 - 0.11 12.8 1.0 0.26 11.6 0.2 1.9 2 0 0 2 2 2 0 PcfK-like protein PH PF00169.29 GAN04644.1 - 1.7e-09 38.1 0.0 2.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAN04644.1 - 0.00013 22.4 0.0 0.0014 19.0 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAN04644.1 - 0.071 13.5 0.3 0.11 13.0 0.3 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain RhoGAP PF00620.27 GAN04647.1 - 1.9e-50 170.6 0.1 5.6e-50 169.1 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 GAN04647.1 - 1.5e-16 60.3 19.8 8.6e-10 38.7 5.1 3.4 3 0 0 3 3 2 2 LIM domain C1_1 PF00130.22 GAN04647.1 - 1.8e-08 34.1 4.2 1.8e-08 34.1 4.2 4.4 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TMF_TATA_bd PF12325.8 GAN04647.1 - 0.00017 21.8 17.1 0.00038 20.7 3.5 3.6 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding C1_2 PF03107.16 GAN04647.1 - 0.00054 20.2 2.5 0.00054 20.2 2.5 4.6 3 2 1 4 4 2 1 C1 domain Bap31_Bap29_C PF18035.1 GAN04647.1 - 0.077 13.0 1.8 0.29 11.2 1.8 2.0 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain KELK PF15796.5 GAN04647.1 - 0.9 10.0 13.5 0.89 10.1 3.8 3.3 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SKA2 PF16740.5 GAN04647.1 - 1.8 8.3 8.6 8.6 6.2 0.6 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 OmpH PF03938.14 GAN04647.1 - 2 8.7 15.2 1.8 8.9 2.0 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 GAN04647.1 - 2.3 8.6 10.4 5.1 7.5 1.2 3.0 2 1 0 2 2 2 0 Tup N-terminal HALZ PF02183.18 GAN04647.1 - 3.6 7.9 7.7 0.32 11.2 0.6 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.8 GAN04647.1 - 3.7 6.8 14.3 2.1 7.6 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 GAN04647.1 - 6.8 6.5 13.1 0.24 11.2 1.0 3.1 2 1 1 3 3 3 0 Septum formation initiator Fez1 PF06818.15 GAN04647.1 - 8.3 6.8 16.9 4.4 7.7 6.5 2.7 3 0 0 3 3 3 0 Fez1 WD40 PF00400.32 GAN04648.1 - 4.7e-16 58.9 10.1 0.082 13.8 0.0 7.1 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04648.1 - 1.7e-11 44.3 0.1 0.00011 22.4 0.0 5.0 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN04648.1 - 0.0014 18.0 0.1 0.0067 15.8 0.0 2.1 1 1 1 2 2 2 1 WD40-like domain RR_TM4-6 PF06459.12 GAN04648.1 - 0.11 12.3 8.6 0.16 11.8 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GAN04648.1 - 0.32 9.2 17.1 0.53 8.5 17.1 1.3 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.8 GAN04648.1 - 0.84 8.7 12.7 1.4 7.9 12.7 1.3 1 0 0 1 1 1 0 SprA-related family Nop14 PF04147.12 GAN04648.1 - 1.4 7.0 19.4 1.9 6.6 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GAN04648.1 - 1.7 8.7 24.3 2.6 8.1 24.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PPP4R2 PF09184.11 GAN04648.1 - 1.8 8.1 16.4 2.9 7.4 16.4 1.3 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 GAN04648.1 - 3.7 8.0 7.0 10 6.6 7.0 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Saw1 PF11561.8 GAN04648.1 - 4 6.9 5.8 7 6.1 5.8 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Nop53 PF07767.11 GAN04648.1 - 6.6 6.0 21.9 10 5.4 21.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sporozoite_P67 PF05642.11 GAN04648.1 - 9 4.2 11.5 12 3.8 11.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Vfa1 PF08432.10 GAN04648.1 - 9.1 6.6 16.6 14 6.0 16.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Baculo_F PF12259.8 GAN04649.1 - 0.017 13.7 6.8 0.028 12.9 6.8 1.3 1 0 0 1 1 1 0 Baculovirus F protein CagE_TrbE_VirB PF03135.14 GAN04649.1 - 0.025 14.7 1.9 0.061 13.4 1.9 1.6 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system NIL PF09383.10 GAN04649.1 - 0.027 14.3 0.4 14 5.6 0.0 3.4 2 1 0 2 2 2 0 NIL domain CorA PF01544.18 GAN04649.1 - 0.077 12.3 10.7 0.16 11.3 10.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein WASH-7_C PF14746.6 GAN04649.1 - 0.19 11.4 8.2 0.94 9.1 8.2 2.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal KxDL PF10241.9 GAN04649.1 - 0.25 11.7 10.4 0.038 14.3 3.7 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF948 PF06103.11 GAN04649.1 - 1.1 9.6 5.6 15 5.9 1.3 3.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Tmemb_cc2 PF10267.9 GAN04649.1 - 4.3 6.4 28.7 0.011 14.9 17.6 2.1 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein Exonuc_VII_L PF02601.15 GAN04649.1 - 8.8 5.8 21.7 5.4 6.5 16.6 2.4 2 1 0 2 2 2 0 Exonuclease VII, large subunit Importin_rep_4 PF18808.1 GAN04650.1 - 7.3e-33 112.7 5.6 6.9e-31 106.4 0.2 5.3 6 0 0 6 6 6 1 Importin repeat Vac14_Fab1_bd PF12755.7 GAN04650.1 - 5.3e-18 65.4 2.5 8.8e-05 23.0 0.0 7.7 4 3 4 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 GAN04650.1 - 5e-17 62.0 6.7 2.1e-06 28.1 0.0 9.7 8 2 4 12 12 11 3 HEAT-like repeat Importin_rep_6 PF18829.1 GAN04650.1 - 5.1e-17 62.0 1.2 3.3e-16 59.3 0.0 2.9 3 0 0 3 3 3 1 Importin repeat 6 HEAT_2 PF13646.6 GAN04650.1 - 1.3e-15 57.5 13.5 4.8e-05 23.7 0.0 9.1 5 3 5 10 10 9 4 HEAT repeats HEAT PF02985.22 GAN04650.1 - 1.2e-13 50.0 14.5 0.0027 17.8 0.0 11.1 12 0 0 12 12 12 2 HEAT repeat CLASP_N PF12348.8 GAN04650.1 - 1e-09 38.3 0.0 0.011 15.3 0.0 4.9 3 1 1 4 4 4 3 CLASP N terminal DUF3385 PF11865.8 GAN04650.1 - 2.4e-09 37.3 5.2 0.0085 16.0 0.2 8.1 5 1 1 8 8 8 2 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 GAN04650.1 - 1.3e-08 33.9 0.4 0.0096 14.5 0.1 4.3 3 1 1 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.8 GAN04650.1 - 7e-08 32.0 0.7 0.23 10.5 0.1 6.7 7 1 1 8 8 8 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 GAN04650.1 - 9.4e-07 29.0 0.5 0.0025 17.9 0.2 4.2 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 GAN04650.1 - 4.9e-06 26.3 0.1 0.18 11.3 0.0 5.0 3 1 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 GAN04650.1 - 0.00018 21.7 1.1 0.079 13.1 0.2 4.9 5 1 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 GAN04650.1 - 0.0011 18.8 1.7 2.6 7.7 0.0 5.2 4 2 1 5 5 5 1 rRNA processing/ribosome biogenesis Importin_rep_5 PF18816.1 GAN04650.1 - 0.0023 18.2 0.5 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 Importin repeat BP28CT PF08146.12 GAN04650.1 - 0.0071 16.2 0.1 3.2 7.6 0.0 4.6 4 1 0 4 4 4 1 BP28CT (NUC211) domain Gag_p30 PF02093.16 GAN04650.1 - 0.054 13.0 0.0 0.71 9.4 0.0 2.4 2 0 0 2 2 2 0 Gag P30 core shell protein V-ATPase_H_N PF03224.14 GAN04650.1 - 0.23 10.7 3.9 1.9 7.7 0.1 3.2 2 1 2 4 4 4 0 V-ATPase subunit H Arm PF00514.23 GAN04650.1 - 0.43 10.7 6.8 25 5.1 0.0 5.5 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 GAN04650.1 - 2.6 8.0 5.9 7.3 6.5 0.3 3.7 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central LRR_6 PF13516.6 GAN04651.1 - 8.5e-09 34.8 33.7 0.014 15.4 0.1 10.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 GAN04651.1 - 1e-05 25.8 28.0 0.12 12.8 0.7 8.2 4 4 5 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN04651.1 - 0.045 14.3 17.0 36 5.4 0.1 8.3 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 GAN04651.1 - 0.048 13.4 0.7 0.048 13.4 0.7 7.0 5 2 3 8 8 8 0 Leucine rich repeat MFS_MOT1 PF16983.5 GAN04652.1 - 3.8e-59 197.9 29.0 7.3e-35 119.7 8.2 3.0 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily TatC PF00902.18 GAN04652.1 - 2.5 7.9 12.0 2.4 7.9 0.6 3.2 2 1 1 3 3 3 0 Sec-independent protein translocase protein (TatC) COG6 PF06419.11 GAN04653.1 - 1.9e-174 581.4 12.7 2.2e-174 581.2 12.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DnaG_DnaB_bind PF08278.11 GAN04653.1 - 0.0058 17.2 1.1 0.52 10.9 0.0 3.3 3 0 0 3 3 3 1 DNA primase DnaG DnaB-binding PspA_IM30 PF04012.12 GAN04653.1 - 0.029 13.9 2.4 4.6 6.8 0.9 3.2 2 1 1 3 3 3 0 PspA/IM30 family BRE1 PF08647.11 GAN04653.1 - 1.1 9.4 5.3 0.95 9.6 0.1 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Peptidase_C50 PF03568.17 GAN04654.1 - 2.8e-110 369.1 0.0 1.1e-109 367.2 0.0 2.1 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 GAN04654.1 - 5.4e-07 29.8 0.1 0.84 10.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat CHAT PF12770.7 GAN04654.1 - 0.0004 19.9 0.1 0.003 17.0 0.0 2.2 2 0 0 2 2 2 1 CHAT domain TPR_1 PF00515.28 GAN04654.1 - 0.0008 19.1 0.0 0.052 13.4 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAN04654.1 - 0.0024 18.0 6.1 3.8 8.0 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF4460 PF14687.6 GAN04654.1 - 0.037 14.1 0.5 0.24 11.5 0.5 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) TPR_2 PF07719.17 GAN04654.1 - 0.1 12.8 0.0 0.1 12.8 0.0 6.2 9 0 0 9 9 9 0 Tetratricopeptide repeat PB1 PF00564.24 GAN04655.1 - 2.8e-08 33.6 0.0 6.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Myosin_head PF00063.21 GAN04656.1 - 1.7e-269 895.8 4.5 2.5e-269 895.2 4.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 GAN04656.1 - 1.7e-17 61.5 41.5 1.1e-05 24.8 1.9 6.9 7 0 0 7 7 7 5 IQ calmodulin-binding motif RRP7 PF12923.7 GAN04656.1 - 0.0053 16.9 1.3 0.015 15.4 1.3 1.8 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain AAA_22 PF13401.6 GAN04656.1 - 0.0082 16.4 0.2 0.04 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 GAN04656.1 - 0.054 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 GAN04656.1 - 0.07 13.0 0.1 0.88 9.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 GAN04656.1 - 0.07 13.5 3.3 0.093 13.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Myosin_N PF02736.19 GAN04656.1 - 0.089 12.6 0.7 0.27 11.1 0.7 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain RNA_helicase PF00910.22 GAN04656.1 - 0.12 12.8 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase HAD_SAK_2 PF18143.1 GAN04656.1 - 0.91 9.8 5.4 0.47 10.7 1.6 2.3 1 1 1 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins DUF2203 PF09969.9 GAN04656.1 - 5.9 7.6 13.0 0.96 10.2 4.6 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ABC_tran PF00005.27 GAN04656.1 - 6.4 7.3 7.7 1.2 9.7 1.4 3.1 2 1 0 2 2 2 0 ABC transporter WW PF00397.26 GAN04657.1 - 1.3e-13 50.7 6.8 1.3e-13 50.7 6.8 1.9 2 0 0 2 2 2 1 WW domain DUF3824 PF12868.7 GAN04657.1 - 0.016 15.9 14.2 0.016 15.9 14.2 4.2 1 1 3 4 4 4 0 Domain of unknwon function (DUF3824) Sec3_C PF09763.9 GAN04658.1 - 0.016 13.6 0.2 0.023 13.1 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Phi_1 PF04674.12 GAN04659.1 - 0.12 11.6 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region MgtE PF01769.16 GAN04660.1 - 0.045 14.1 0.3 0.045 14.1 0.3 2.2 2 1 0 2 2 2 0 Divalent cation transporter Ist1 PF03398.14 GAN04661.1 - 2.2e-64 216.3 2.3 5.5e-64 215.0 2.3 1.8 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway UPF0220 PF05255.11 GAN04661.1 - 4.5e-37 127.2 0.6 9.8e-37 126.1 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) zf-RING_4 PF14570.6 GAN04661.1 - 3.5e-22 77.9 12.1 7.3e-22 76.9 12.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GAN04661.1 - 4.1e-07 29.8 9.0 7.6e-07 28.9 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN04661.1 - 0.00021 21.1 8.8 0.0058 16.5 9.3 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 GAN04661.1 - 0.00088 19.0 0.0 0.01 15.6 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 GAN04661.1 - 0.0036 17.6 11.7 0.0071 16.7 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 GAN04661.1 - 0.023 14.7 4.6 0.06 13.3 4.6 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FANCI_S2 PF14676.6 GAN04661.1 - 0.029 14.7 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 FANCI solenoid 2 zf-UDP PF14569.6 GAN04661.1 - 0.029 14.5 3.2 0.069 13.3 3.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 GAN04661.1 - 0.036 14.0 10.6 0.072 13.0 10.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN04661.1 - 0.055 13.3 10.6 0.11 12.4 10.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN04661.1 - 0.58 10.2 6.3 0.77 9.8 5.3 1.8 1 1 0 1 1 1 0 RING-type zinc-finger ICMT PF04140.14 GAN04662.1 - 2.4e-23 82.4 1.8 2.4e-23 82.4 1.8 1.8 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAN04662.1 - 9.7e-11 42.0 0.9 9.7e-11 42.0 0.9 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAN04662.1 - 3.3e-05 23.5 2.5 3.3e-05 23.5 2.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) F-box-like PF12937.7 GAN04663.1 - 0.00012 21.9 0.5 0.00043 20.1 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04663.1 - 0.32 10.9 2.4 2.7 8.0 2.4 2.5 1 1 0 1 1 1 0 F-box domain ERM PF00769.19 GAN04664.1 - 6.1 6.6 40.5 1.4 8.7 34.2 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RNB PF00773.19 GAN04665.1 - 1.7e-44 152.5 0.3 1.1e-43 149.9 0.3 2.4 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAN04665.1 - 2.2e-18 66.1 0.0 5.6e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 GAN04665.1 - 0.00061 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 GAN04665.1 - 0.02 15.2 0.1 0.08 13.3 0.1 2.1 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal NifT PF06988.11 GAN04665.1 - 0.14 11.9 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 NifT/FixU protein V-SNARE_C PF12352.8 GAN04666.1 - 0.0022 18.2 1.5 0.081 13.2 0.3 2.9 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Voltage_CLC PF00654.20 GAN04667.1 - 8.2e-89 298.3 29.7 2.8e-88 296.6 28.2 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAN04667.1 - 2.5e-12 47.0 0.2 5.4e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 CBS domain Phage_holin_3_1 PF05106.12 GAN04667.1 - 3.5 8.1 9.6 17 5.9 2.1 4.5 4 0 0 4 4 4 0 Phage holin family (Lysis protein S) RT_RNaseH_2 PF17919.1 GAN04668.1 - 3.6e-30 103.9 0.0 5e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAN04668.1 - 4e-28 97.8 0.0 5.7e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GAN04669.1 - 3.2e-18 66.1 0.0 5.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 GAN04669.1 - 4.2e-05 23.2 0.0 0.00017 21.3 0.0 2.1 1 1 1 2 2 2 1 Integrase core domain BTG PF07742.12 GAN04669.1 - 0.19 11.6 0.5 0.79 9.6 0.1 2.3 3 1 0 3 3 3 0 BTG family Ammonium_transp PF00909.21 GAN04670.1 - 3.5e-109 365.1 29.7 4.2e-109 364.9 29.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PrmA PF06325.13 GAN04671.1 - 7.5e-06 25.6 0.1 1.2e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAN04671.1 - 1.1e-05 26.0 0.0 4.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN04671.1 - 0.00011 22.8 0.0 0.00036 21.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN04671.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAN04671.1 - 0.0021 17.6 0.0 0.006 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 GAN04671.1 - 0.0027 17.4 0.1 0.37 10.4 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 PRMT5_C PF17286.2 GAN04671.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 PRMT5 oligomerisation domain GidB PF02527.15 GAN04671.1 - 0.079 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Suc_Fer-like PF06999.12 GAN04672.1 - 3.8e-42 144.4 0.0 4.9e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Sec2p PF06428.11 GAN04673.1 - 2.1e-22 78.9 13.9 2.1e-22 78.9 13.9 2.8 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p UvrD-helicase PF00580.21 GAN04673.1 - 0.026 14.0 10.4 0.043 13.3 10.4 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Dscam_C PF12355.8 GAN04673.1 - 0.056 14.4 2.5 0.17 12.9 2.5 1.7 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal V_ATPase_I PF01496.19 GAN04673.1 - 0.086 10.8 15.8 0.017 13.1 12.3 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Flagellin_C PF00700.21 GAN04673.1 - 0.25 11.7 5.7 5.6 7.4 1.0 2.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region OmpH PF03938.14 GAN04673.1 - 1.1 9.6 29.1 0.8 10.0 12.9 2.5 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 GAN04673.1 - 1.7 8.8 19.8 9.2 6.4 7.3 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 GAN04673.1 - 2.2 8.6 17.9 7.3 6.9 11.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Tropomyosin PF00261.20 GAN04673.1 - 2.4 7.4 29.0 0.34 10.2 18.4 2.3 1 1 1 2 2 2 0 Tropomyosin MAD PF05557.13 GAN04673.1 - 2.5 6.3 30.4 0.26 9.6 8.7 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Nas2_N PF18265.1 GAN04673.1 - 5 7.1 21.8 1.4 8.9 5.1 5.1 4 1 0 4 4 4 0 Nas2 N_terminal domain TMPIT PF07851.13 GAN04673.1 - 5.1 6.2 15.8 1.3 8.2 4.8 2.2 1 1 1 2 2 2 0 TMPIT-like protein Exonuc_VII_L PF02601.15 GAN04673.1 - 6.8 6.2 18.9 2.2 7.8 8.2 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit UPF0449 PF15136.6 GAN04673.1 - 9.3 6.8 11.6 2.6 8.6 1.6 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Xpo1 PF08389.12 GAN04674.1 - 3.6e-39 134.2 1.1 4e-36 124.3 0.4 3.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 GAN04674.1 - 7.1e-08 32.3 0.1 1.5e-06 28.0 0.1 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 GAN04674.1 - 0.11 12.9 0.1 0.73 10.3 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats Sec1 PF00995.23 GAN04675.1 - 6e-108 362.6 4.6 4.9e-84 283.6 0.4 2.0 1 1 1 2 2 2 2 Sec1 family Terminase_4 PF05119.12 GAN04675.1 - 0.15 12.5 0.4 5.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Phage terminase, small subunit Transket_pyr PF02779.24 GAN04676.1 - 2.7e-46 157.5 0.0 5.3e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAN04676.1 - 4e-39 133.3 0.0 9.4e-39 132.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GAN04676.1 - 0.02 15.2 0.0 0.09 13.1 0.0 2.0 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II Pkinase PF00069.25 GAN04677.1 - 4.9e-72 242.5 0.1 2e-71 240.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04677.1 - 1.9e-33 115.8 0.0 9.5e-33 113.6 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04677.1 - 3.3e-07 29.9 1.3 0.049 12.9 0.0 3.5 2 1 1 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 GAN04677.1 - 0.0086 14.9 1.4 0.029 13.1 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAN04677.1 - 0.32 10.9 0.1 0.32 10.9 0.1 3.1 3 2 1 4 4 4 0 Phosphotransferase enzyme family DUF4451 PF14616.6 GAN04678.1 - 7.3e-16 58.5 7.8 1.8e-15 57.2 7.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) WD40 PF00400.32 GAN04679.1 - 1.2e-38 130.3 26.6 8.3e-06 26.5 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat WD40_like PF17005.5 GAN04679.1 - 5.6e-10 39.0 0.8 2.4e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 GAN04679.1 - 6.4e-09 36.0 3.1 0.74 10.1 0.0 5.3 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN04679.1 - 1.2e-07 30.8 8.1 0.12 11.0 0.0 5.7 3 3 2 6 6 6 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAN04679.1 - 0.00012 22.1 0.3 12 6.0 0.1 4.8 3 2 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 GAN04679.1 - 0.0016 18.9 0.0 0.35 11.4 0.0 3.7 4 0 0 4 4 4 1 PQQ-like domain F-box-like PF12937.7 GAN04679.1 - 0.0018 18.1 0.6 0.0033 17.3 0.6 1.4 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 GAN04679.1 - 0.011 15.4 0.1 0.13 11.9 0.0 2.3 1 1 1 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 GAN04679.1 - 0.012 14.6 2.1 1.4 7.8 0.2 3.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box PF00646.33 GAN04679.1 - 0.046 13.6 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 F-box domain eIF2A PF08662.11 GAN04679.1 - 0.065 13.1 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A RVT_1 PF00078.27 GAN04681.1 - 6e-08 32.5 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 GAN04682.1 - 4.2e-09 36.3 0.2 5.5e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CNH PF00780.22 GAN04683.1 - 7.1e-55 186.5 0.0 1.1e-54 185.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAN04683.1 - 1.1e-31 110.4 3.2 1.1e-31 110.4 3.2 1.8 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 GAN04683.1 - 2.5e-16 60.0 4.8 2.7e-16 59.9 0.0 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 GAN04683.1 - 0.05 13.4 0.0 0.05 13.4 0.0 2.5 3 1 0 3 3 3 0 Pleckstrin homology domain PH PF00169.29 GAN04683.1 - 0.13 12.8 0.0 1 9.9 0.0 2.6 1 1 0 1 1 1 0 PH domain Band_3_cyto PF07565.13 GAN04683.1 - 1.9 8.2 4.6 3.6 7.3 4.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PIEZO PF15917.5 GAN04683.1 - 3 7.3 8.2 6.1 6.3 8.2 1.4 1 0 0 1 1 1 0 Piezo Ndc1_Nup PF09531.10 GAN04683.1 - 5.7 5.5 5.8 12 4.4 5.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAS_9 PF13426.7 GAN04684.1 - 5.9e-24 84.3 0.0 2.8e-16 59.7 0.0 3.7 2 1 2 4 4 4 3 PAS domain PAS_3 PF08447.12 GAN04684.1 - 8.7e-21 74.0 0.0 1e-12 48.1 0.0 4.0 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 GAN04684.1 - 1.8e-15 56.2 3.3 3.9e-15 55.2 3.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 GAN04684.1 - 1.6e-13 50.9 0.0 3e-06 27.4 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 GAN04684.1 - 2e-09 37.4 0.0 0.0017 18.3 0.0 3.9 3 1 0 3 3 3 2 PAS fold PAS_11 PF14598.6 GAN04684.1 - 2.6e-09 37.2 0.0 1e-05 25.6 0.0 3.5 4 0 0 4 4 4 2 PAS domain DUF4763 PF15960.5 GAN04684.1 - 0.0035 16.7 1.4 0.0076 15.6 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) OrfB_Zn_ribbon PF07282.11 GAN04684.1 - 0.034 14.1 1.1 0.085 12.8 1.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF678 PF05077.12 GAN04684.1 - 2.5 8.3 7.8 0.16 12.1 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Pkinase PF00069.25 GAN04685.1 - 1.5e-67 227.8 0.0 1.8e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04685.1 - 4.6e-30 104.8 0.0 7.2e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAN04685.1 - 0.00072 19.0 0.5 0.0014 18.0 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN04685.1 - 0.003 16.5 0.7 0.0068 15.4 0.7 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN04685.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAN04685.1 - 0.11 11.2 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Fes1 PF08609.10 GAN04686.1 - 2e-22 79.9 1.0 2e-22 79.9 1.0 2.9 3 1 1 4 4 4 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 GAN04686.1 - 3.2e-08 33.1 0.0 0.029 14.6 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 GAN04686.1 - 4.2e-06 26.6 0.0 0.021 14.9 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAN04686.1 - 1.2e-05 25.5 0.3 0.0013 19.1 0.0 3.4 3 1 1 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 GAN04686.1 - 9.2e-05 21.2 0.2 0.029 13.0 0.2 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GAN04686.1 - 0.0002 21.5 0.1 0.001 19.2 0.1 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAN04686.1 - 0.00047 20.6 0.0 0.013 15.9 0.0 2.8 1 1 1 2 2 2 2 HEAT-like repeat V-ATPase_H_C PF11698.8 GAN04686.1 - 0.0015 18.7 2.7 2 8.5 0.0 3.3 1 1 2 3 3 3 1 V-ATPase subunit H Nop52 PF05997.12 GAN04686.1 - 0.057 13.2 0.5 0.5 10.1 0.0 2.3 1 1 1 2 2 2 0 Nucleolar protein,Nop52 MRP-S26 PF14943.6 GAN04688.1 - 0.0022 17.9 15.7 0.0022 17.9 15.7 2.0 1 1 1 2 2 2 1 Mitochondrial ribosome subunit S26 Homeobox_KN PF05920.11 GAN04689.1 - 1e-18 66.9 2.0 1e-18 66.9 2.0 2.5 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 GAN04689.1 - 6.7e-08 32.3 0.4 1.5e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 Homeodomain BTB_2 PF02214.22 GAN04691.1 - 1.6e-17 63.6 0.9 3.1e-17 62.7 0.9 1.4 1 0 0 1 1 1 1 BTB/POZ domain CALCOCO1 PF07888.11 GAN04691.1 - 0.017 14.0 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BTB_2 PF02214.22 GAN04692.1 - 1.1e-19 70.5 0.5 1.8e-19 69.9 0.5 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAN04692.1 - 2.7e-05 24.3 0.1 4.6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 GAN04693.1 - 1e-14 54.6 0.3 1.6e-14 54.0 0.3 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAN04693.1 - 0.014 15.6 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 GAN04694.1 - 4.1e-16 59.1 0.8 5e-16 58.8 0.8 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAN04694.1 - 0.00052 20.2 0.2 0.00062 20.0 0.2 1.1 1 0 0 1 1 1 1 BTB/POZ domain DisA_N PF02457.16 GAN04694.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding CNH PF00780.22 GAN04695.1 - 1.8e-61 208.2 0.0 1.2e-60 205.5 0.0 2.4 2 1 0 2 2 2 1 CNH domain RhoGEF PF00621.20 GAN04695.1 - 8.6e-36 123.9 0.5 2.4e-35 122.4 0.1 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 GAN04695.1 - 1.4e-30 106.1 0.6 4.6e-30 104.5 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 GAN04695.1 - 1.1e-12 47.8 0.1 2.6e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SR-25 PF10500.9 GAN04696.1 - 6.2e-17 62.0 18.0 5e-16 59.0 18.0 1.8 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein Uso1_p115_head PF04869.14 GAN04696.1 - 0.0027 16.9 0.1 0.003 16.7 0.1 1.0 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region ESM4 PF15952.5 GAN04696.1 - 0.14 12.6 5.3 0.19 12.1 5.3 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family CENP-H PF05837.12 GAN04696.1 - 1.6 9.1 7.4 1.6 9.1 6.4 1.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DSPc PF00782.20 GAN04698.1 - 4.8e-35 120.3 0.1 3.2e-23 82.0 0.1 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN04698.1 - 0.00011 21.8 0.0 0.061 12.9 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 GAN04698.1 - 0.017 15.4 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Rit1 DUSP-like domain CDKN3 PF05706.12 GAN04698.1 - 0.048 13.3 0.4 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 GAN04698.1 - 0.15 12.0 0.0 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family BCL9 PF11502.8 GAN04698.1 - 0.28 11.0 1.5 1.5 8.7 0.1 2.7 3 0 0 3 3 3 0 B-cell lymphoma 9 protein TAF8_C PF10406.9 GAN04699.1 - 1.7e-17 63.7 2.0 1.7e-17 63.7 2.0 2.5 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 GAN04699.1 - 4.4e-14 52.2 0.0 8.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 GAN04699.1 - 0.022 14.9 0.6 0.041 14.0 0.1 1.8 2 1 1 3 3 3 0 Histone-fold protein Syntaxin_2 PF14523.6 GAN04699.1 - 0.27 11.6 5.1 4.1 7.8 0.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Med9 PF07544.13 GAN04699.1 - 2.1 8.5 5.6 6.9 6.8 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.21 GAN04700.1 - 5.3e-09 36.0 12.5 1.6e-08 34.5 12.5 1.9 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 GAN04700.1 - 2.7e-07 30.7 0.0 2.7e-07 30.7 0.0 3.1 2 1 1 3 3 3 1 Transcription factor PAP1 bZIP_2 PF07716.15 GAN04700.1 - 0.00026 21.0 13.0 0.00072 19.6 5.6 2.5 2 0 0 2 2 2 2 Basic region leucine zipper CCDC85 PF10226.9 GAN04700.1 - 0.0018 18.0 2.4 0.009 15.7 0.6 2.4 2 0 0 2 2 2 1 CCDC85 family PRKG1_interact PF15898.5 GAN04700.1 - 8.3 7.4 13.0 0.21 12.5 5.6 2.1 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Radical_SAM PF04055.21 GAN04701.1 - 3.6e-33 115.3 0.1 9.1e-33 114.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 GAN04701.1 - 2.8e-27 94.6 0.1 6.4e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 GAN04701.1 - 3.3e-05 23.8 0.1 9.3e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 TRAM domain Complex1_LYR PF05347.15 GAN04701.1 - 0.00047 20.2 0.1 0.002 18.2 0.0 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) G-alpha PF00503.20 GAN04702.1 - 1.2e-110 370.1 0.3 1.3e-110 369.9 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN04702.1 - 1.6e-12 47.3 0.7 2.1e-08 33.8 0.0 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN04702.1 - 0.00062 19.2 0.5 0.12 11.7 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 GAN04702.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 GAN04702.1 - 0.036 14.3 0.0 6 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 GAN04702.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SASA PF03629.18 GAN04703.1 - 9.6e-57 192.2 0.0 1.4e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Clr5 PF14420.6 GAN04703.1 - 0.071 13.3 0.4 2.1 8.6 0.1 2.5 2 0 0 2 2 2 0 Clr5 domain TPR_11 PF13414.6 GAN04705.1 - 0.0061 16.2 2.0 0.034 13.8 0.2 3.1 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 GAN04705.1 - 0.085 13.1 1.1 54 4.1 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 GAN04705.1 - 0.18 11.8 4.6 7.4 6.6 0.1 3.3 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 TPR_1 PF00515.28 GAN04705.1 - 0.49 10.3 3.3 1.1 9.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAN04705.1 - 0.49 10.9 8.1 14 6.3 0.1 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN04705.1 - 1.3 10.1 4.9 24 6.1 0.1 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 GAN04705.1 - 1.6 8.9 11.6 5.9 7.0 0.2 4.5 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 GAN04705.1 - 1.8 8.8 5.4 1 9.6 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 GAN04706.1 - 2.9e-75 252.3 0.0 7.9e-75 250.9 0.0 1.8 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Las1 PF04031.13 GAN04706.1 - 1.1e-48 165.3 0.2 2.2e-48 164.2 0.2 1.6 1 0 0 1 1 1 1 Las1-like Methyltr_RsmF_N PF17125.5 GAN04706.1 - 7.4e-09 36.0 0.0 8.1e-08 32.7 0.0 2.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 GAN04706.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 GAN04706.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase VIT1 PF01988.19 GAN04706.1 - 8.3 6.2 5.6 29 4.4 5.6 1.9 1 0 0 1 1 1 0 VIT family Methyltransf_25 PF13649.6 GAN04708.1 - 2.2e-16 60.3 0.0 5.4e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN04708.1 - 1.1e-14 54.6 0.2 9e-14 51.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN04708.1 - 2.4e-14 53.8 0.0 5.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN04708.1 - 2.4e-12 47.0 0.4 5e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN04708.1 - 4.1e-09 37.1 0.0 2e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN04708.1 - 2.3e-07 30.4 0.0 5.2e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN04708.1 - 4.4e-07 29.5 0.7 0.00012 21.6 0.0 2.8 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_2 PF00891.18 GAN04708.1 - 2.4e-05 23.7 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 GAN04708.1 - 0.00021 21.2 0.0 0.00058 19.8 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase CheR PF01739.18 GAN04708.1 - 0.00059 19.4 0.3 0.0055 16.2 0.0 2.5 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 GAN04708.1 - 0.00098 18.7 0.0 0.041 13.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 GAN04708.1 - 0.0014 18.3 0.0 0.003 17.2 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 GAN04708.1 - 0.0049 15.5 0.1 0.019 13.5 0.1 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.14 GAN04708.1 - 0.01 15.3 0.0 0.026 13.9 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 GAN04708.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Herpes_VP19C PF03327.14 GAN04708.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C Ribosomal_L18A PF01775.17 GAN04710.1 - 9.4e-35 119.3 0.4 1.2e-34 119.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A GATA PF00320.27 GAN04711.1 - 5.1e-12 45.2 6.4 1.3e-11 43.9 6.4 1.7 1 0 0 1 1 1 1 GATA zinc finger SAE2 PF08573.10 GAN04711.1 - 5.7 8.1 10.5 0.35 12.0 1.0 3.5 3 0 0 3 3 3 0 DNA repair protein endonuclease SAE2/CtIP C-terminus La PF05383.17 GAN04712.1 - 3.4e-25 87.9 0.0 6.2e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAN04712.1 - 0.00012 21.8 0.3 0.0004 20.2 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 GAN04713.1 - 0.00012 22.1 13.5 0.00023 21.2 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4611 PF15387.6 GAN04713.1 - 0.06 13.6 7.7 0.13 12.5 2.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Nefa_Nip30_N PF10187.9 GAN04714.1 - 1.1e-17 64.3 16.8 1.1e-17 64.3 16.8 2.2 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 ALMT PF11744.8 GAN04714.1 - 5.7 5.7 7.9 6.6 5.4 7.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RRM_1 PF00076.22 GAN04715.1 - 7.9e-11 41.6 1.2 1.8e-05 24.5 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN04715.1 - 2e-08 34.1 0.2 0.0006 19.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 GAN04715.1 - 7.8e-05 22.5 2.1 0.00017 21.4 2.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF812 PF05667.11 GAN04715.1 - 0.0001 21.3 10.9 0.00016 20.7 10.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PWI PF01480.17 GAN04715.1 - 0.00025 21.3 0.1 0.00068 19.9 0.0 1.7 2 0 0 2 2 2 1 PWI domain zf_CCCH_4 PF18345.1 GAN04715.1 - 0.00039 20.4 2.2 0.00088 19.3 2.2 1.7 1 0 0 1 1 1 1 Zinc finger domain RRM_occluded PF16842.5 GAN04715.1 - 0.026 14.4 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf-CCCH_2 PF14608.6 GAN04715.1 - 0.47 11.0 2.6 0.79 10.3 2.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 GAN04715.1 - 0.64 10.1 0.0 0.64 10.1 0.0 3.7 4 0 0 4 4 4 0 RNA binding motif DDHD PF02862.17 GAN04715.1 - 1.4 9.0 8.1 1.1 9.3 3.0 2.3 2 0 0 2 2 2 0 DDHD domain CpxA_peri PF16527.5 GAN04715.1 - 1.8 8.9 6.7 1.1 9.7 4.1 1.9 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain Ribosomal_L29 PF00831.23 GAN04715.1 - 6 6.9 13.0 16 5.5 6.8 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein DUF1077 PF06417.12 GAN04716.1 - 4.3e-24 84.8 4.2 5.4e-24 84.5 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) 7TM_GPCR_Srh PF10318.9 GAN04717.1 - 0.087 11.8 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh MAPEG PF01124.18 GAN04718.1 - 0.13 12.2 11.4 0.54 10.2 11.4 1.9 1 1 0 1 1 1 0 MAPEG family DUF4834 PF16118.5 GAN04718.1 - 0.28 12.2 0.4 39 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DEAD PF00270.29 GAN04719.1 - 3e-27 95.5 0.0 5.8e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 GAN04719.1 - 1.4e-16 61.0 1.4 8.2e-16 58.5 0.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 GAN04719.1 - 7.5e-15 55.2 0.0 6.5e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN04719.1 - 0.00086 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 GAN04719.1 - 0.16 12.2 0.3 0.52 10.6 0.1 2.0 2 0 0 2 2 2 0 DNA replication factor CDT1 like Med19 PF10278.9 GAN04721.1 - 0.023 14.6 18.7 0.16 11.9 18.7 2.3 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_polI_A34 PF08208.11 GAN04721.1 - 3.2 7.8 17.2 5 7.2 17.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SelP_N PF04592.14 GAN04721.1 - 3.9 6.8 10.3 5.1 6.4 10.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 GAN04721.1 - 5.6 6.1 5.1 7.1 5.7 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Coilin_N PF15862.5 GAN04721.1 - 7.3 6.4 10.2 10 5.9 10.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus IPPT PF01715.17 GAN04723.1 - 8.7e-60 202.4 0.0 3.6e-59 200.3 0.0 1.9 1 1 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 GAN04723.1 - 9.9e-05 22.5 0.5 0.0018 18.4 0.0 3.0 4 0 0 4 4 4 1 AAA domain IPT PF01745.16 GAN04723.1 - 0.0057 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase PRK PF00485.18 GAN04723.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 GAN04723.1 - 0.022 15.2 0.0 0.064 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 GAN04723.1 - 0.024 14.2 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 GAN04723.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAN04723.1 - 0.043 13.5 0.1 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAN04723.1 - 0.1 12.2 0.3 9.8 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAN04723.1 - 0.17 11.8 0.1 0.48 10.3 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase CbiA PF01656.23 GAN04723.1 - 0.22 11.6 0.6 0.37 10.8 0.6 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 GAN04723.1 - 0.59 10.7 3.2 3.6 8.1 3.2 2.7 1 1 0 1 1 1 0 ABC transporter HSF_DNA-bind PF00447.17 GAN04724.1 - 3.6e-26 91.6 0.0 1.9e-25 89.3 0.0 2.3 1 0 0 1 1 1 1 HSF-type DNA-binding RVT_1 PF00078.27 GAN04725.1 - 8.7e-05 22.1 0.0 0.00018 21.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 GAN04726.1 - 2.4e-30 104.2 0.0 2.6e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN04726.1 - 0.0086 16.2 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif SDA1 PF05285.12 GAN04726.1 - 0.049 13.1 29.9 0.067 12.6 29.9 1.2 1 0 0 1 1 1 0 SDA1 Nup35_RRM_2 PF14605.6 GAN04726.1 - 0.059 13.4 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Apt1 PF10351.9 GAN04726.1 - 0.12 11.2 18.8 0.16 10.8 18.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain LAP1C PF05609.12 GAN04726.1 - 0.29 10.2 18.9 0.34 9.9 18.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 GAN04726.1 - 0.74 8.5 20.2 0.98 8.1 20.2 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GAN04726.1 - 1.8 7.0 20.2 2.3 6.7 20.2 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 GAN04726.1 - 1.9 7.1 9.9 2.2 6.8 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PA26 PF04636.13 GAN04726.1 - 1.9 7.3 12.0 2.8 6.8 12.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Mem_trans PF03547.18 GAN04726.1 - 2.2 6.6 6.9 2.3 6.5 6.9 1.2 1 0 0 1 1 1 0 Membrane transport protein SR-25 PF10500.9 GAN04726.1 - 2.3 7.7 52.9 1.6 8.3 29.5 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GAN04726.1 - 8.8 4.5 26.8 13 3.9 26.8 1.1 1 0 0 1 1 1 0 CDC45-like protein HAP1_N PF04849.13 GAN04727.1 - 0.00017 20.9 8.5 0.049 12.8 0.8 2.2 1 1 1 2 2 2 2 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.9 GAN04727.1 - 0.00031 20.8 7.3 0.045 13.8 2.8 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TssO PF17561.2 GAN04727.1 - 0.0043 17.2 0.3 0.0043 17.2 0.3 2.2 2 0 0 2 2 2 1 Type VI secretion system, TssO Spc7 PF08317.11 GAN04727.1 - 0.018 13.9 4.8 0.015 14.2 3.0 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein YopH_N PF09013.10 GAN04727.1 - 0.035 14.3 0.4 0.41 10.9 0.1 2.6 3 0 0 3 3 3 0 YopH, N-terminal COG7 PF10191.9 GAN04727.1 - 0.042 12.1 5.3 0.55 8.4 1.2 2.0 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) TPR_MLP1_2 PF07926.12 GAN04727.1 - 0.043 13.9 5.0 0.067 13.2 0.3 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein WEMBL PF05701.11 GAN04727.1 - 0.062 12.0 7.3 0.078 11.7 7.3 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light BORCS8 PF10167.9 GAN04727.1 - 0.073 13.0 4.3 0.97 9.4 0.4 2.5 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 8 DUF4349 PF14257.6 GAN04727.1 - 0.11 11.9 3.0 0.29 10.5 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) TMPIT PF07851.13 GAN04727.1 - 0.21 10.8 5.7 0.64 9.2 1.0 2.1 1 1 0 2 2 2 0 TMPIT-like protein COG2 PF06148.11 GAN04727.1 - 0.33 11.0 4.3 3.4 7.8 1.4 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 GAN04727.1 - 0.45 9.8 8.2 0.49 9.7 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4795 PF16043.5 GAN04727.1 - 0.45 10.1 6.2 5.6 6.5 6.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4164 PF13747.6 GAN04727.1 - 0.47 10.8 6.0 0.36 11.1 0.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF724 PF05266.14 GAN04727.1 - 0.52 10.1 7.2 5.8 6.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ApoL PF05461.11 GAN04727.1 - 0.54 9.5 6.4 1.4 8.2 0.6 2.4 1 1 1 2 2 2 0 Apolipoprotein L DivIVA PF05103.13 GAN04727.1 - 0.6 10.2 7.2 0.54 10.4 1.1 2.3 1 1 1 2 2 2 0 DivIVA protein MscS_porin PF12795.7 GAN04727.1 - 0.94 9.0 9.1 1.6 8.2 0.5 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 GAN04727.1 - 1.1 9.3 5.6 10 6.2 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 GAN04727.1 - 2.3 8.0 8.9 3.2 7.6 0.4 2.1 1 1 1 2 2 2 0 PIN like domain Latarcin PF10279.9 GAN04727.1 - 4.4 7.8 6.1 74 3.8 6.1 2.4 1 1 0 1 1 1 0 Latarcin precursor DUF4407 PF14362.6 GAN04727.1 - 5.3 6.3 6.7 20 4.4 6.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 GAN04727.1 - 6.4 7.0 9.9 4.6 7.4 0.9 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YabA PF06156.13 GAN04727.1 - 6.5 7.5 10.8 6.1 7.6 3.0 3.3 2 1 0 3 3 2 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 GAN04727.1 - 8.4 7.1 9.0 2.1 9.0 3.2 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ank_2 PF12796.7 GAN04728.1 - 1.9e-08 34.7 0.1 1e-07 32.4 0.0 2.3 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN04728.1 - 2.5e-07 30.8 0.5 0.00034 20.8 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF629 PF04780.12 GAN04728.1 - 1.2e-06 27.4 8.1 0.4 9.1 0.1 4.2 3 1 1 4 4 4 4 Protein of unknown function (DUF629) Ank PF00023.30 GAN04728.1 - 7.3e-06 26.2 2.7 0.01 16.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAN04728.1 - 4.4e-05 24.0 0.1 0.0011 19.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN04728.1 - 5.7e-05 23.2 1.8 0.16 12.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-C2H2_jaz PF12171.8 GAN04728.1 - 0.0013 18.9 17.0 0.11 12.9 4.3 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAN04728.1 - 0.002 18.8 35.6 1.7 9.7 4.0 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 GAN04728.1 - 0.0027 18.0 17.1 0.017 15.5 1.7 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAN04728.1 - 0.022 15.1 13.5 0.57 10.5 3.4 4.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 GAN04728.1 - 0.023 14.8 0.5 0.023 14.8 0.5 3.5 4 0 0 4 4 4 0 Aberrant zinc-finger Mut7-C PF01927.16 GAN04728.1 - 0.17 12.0 2.3 1.4 9.0 0.0 2.7 2 2 0 2 2 2 0 Mut7-C RNAse domain zinc_ribbon_15 PF17032.5 GAN04728.1 - 0.97 10.2 7.3 0.46 11.3 0.9 2.7 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_12 PF18658.1 GAN04728.1 - 2.4 7.8 7.7 2.4 7.8 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger C2H2-type zf-Di19 PF05605.12 GAN04728.1 - 3 8.2 10.3 5.9 7.3 0.1 4.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding LIN37 PF15306.6 GAN04728.1 - 6.8 6.9 11.8 7.2 6.8 7.1 2.7 2 1 1 3 3 3 0 LIN37 Thymidylate_kin PF02223.17 GAN04729.1 - 1.1e-48 165.4 0.0 1.3e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 GAN04729.1 - 0.0013 19.3 0.2 0.0055 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAN04729.1 - 0.0027 18.0 0.1 0.0065 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 GAN04729.1 - 0.021 14.3 0.2 0.038 13.5 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 GAN04729.1 - 0.024 15.0 1.0 0.26 11.7 0.2 2.6 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 GAN04729.1 - 0.03 13.3 0.0 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 GAN04729.1 - 0.039 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAN04729.1 - 0.05 13.6 0.9 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAN04729.1 - 0.058 13.6 0.1 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 GAN04729.1 - 0.1 12.5 0.3 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DLIC PF05783.11 GAN04730.1 - 6.2e-59 200.1 9.8 3.1e-51 174.7 4.7 4.1 2 1 1 3 3 3 2 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 GAN04730.1 - 0.0017 18.8 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 GAN04730.1 - 0.0096 16.4 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 GAN04730.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAN04730.1 - 0.02 14.8 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 GAN04730.1 - 0.022 14.5 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN04730.1 - 0.025 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 GAN04730.1 - 0.036 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 GAN04730.1 - 0.052 13.5 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 GAN04730.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 GAN04730.1 - 0.1 13.0 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 GAN04730.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_18 PF13238.6 GAN04730.1 - 0.12 12.9 0.0 0.46 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAN04730.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 NTPase KilA-N PF04383.13 GAN04732.1 - 0.0012 18.7 1.0 0.0034 17.2 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain E1-E2_ATPase PF00122.20 GAN04733.1 - 1.1e-50 171.7 0.8 1.1e-50 171.7 0.8 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN04733.1 - 1.4e-47 161.8 8.9 1.4e-47 161.8 8.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAN04733.1 - 7.1e-24 85.3 2.2 2.4e-23 83.5 0.3 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN04733.1 - 2.9e-19 68.9 0.1 5.6e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN04733.1 - 3.3e-19 68.3 0.1 7.3e-19 67.2 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN04733.1 - 3.8e-08 33.4 2.1 4.8e-07 29.8 1.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN04733.1 - 9.6e-06 26.1 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EI24 PF07264.11 GAN04734.1 - 0.08 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.6 GAN04734.1 - 0.45 10.2 2.3 0.93 9.1 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) zf-C2H2 PF00096.26 GAN04735.1 - 2.6e-13 49.6 23.0 1.1e-05 25.5 2.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN04735.1 - 1.1e-12 47.8 19.3 1.3e-05 25.4 1.8 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN04735.1 - 1.5e-08 34.7 21.5 0.0017 19.0 2.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN04735.1 - 4.8e-06 26.4 17.5 0.014 15.4 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 GAN04735.1 - 2.4e-05 24.7 12.8 8.7e-05 22.9 0.1 3.9 1 1 2 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger TSC22 PF01166.18 GAN04735.1 - 0.0062 16.8 4.9 0.2 12.0 1.0 2.5 1 1 1 2 2 2 2 TSC-22/dip/bun family zf-H2C2_5 PF13909.6 GAN04735.1 - 0.014 15.1 1.7 0.014 15.1 1.7 2.9 2 1 0 2 2 1 0 C2H2-type zinc-finger domain zf-MYST PF17772.1 GAN04735.1 - 0.055 13.1 5.0 3.9 7.2 0.8 3.3 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 GAN04735.1 - 0.093 12.7 3.6 0.14 12.0 0.4 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 GAN04735.1 - 0.11 12.3 5.4 0.38 10.6 0.8 2.7 1 1 1 2 2 2 0 GAGA factor BolA PF01722.18 GAN04735.1 - 0.2 12.0 4.4 2.1 8.7 1.3 2.7 2 1 1 3 3 3 0 BolA-like protein ADK_lid PF05191.14 GAN04735.1 - 0.54 10.3 6.6 0.097 12.7 0.6 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF5595 PF18077.1 GAN04735.1 - 2.2 8.4 4.6 11 6.1 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) zf-C2H2_jaz PF12171.8 GAN04735.1 - 4.6 7.7 15.7 5.4 7.4 1.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 GAN04735.1 - 5.3 7.1 8.8 1.2 9.2 3.3 2.8 1 1 1 2 2 2 0 BED zinc finger zf_UBZ PF18439.1 GAN04735.1 - 5.8 6.6 9.5 3.3 7.4 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DivIC PF04977.15 GAN04735.1 - 7.9 6.3 7.3 12 5.7 5.9 2.0 1 1 0 1 1 1 0 Septum formation initiator p450 PF00067.22 GAN04736.1 - 2.6e-73 247.4 0.0 3.3e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MgtE PF01769.16 GAN04737.1 - 0.078 13.4 4.3 0.09 13.2 4.3 1.2 1 0 0 1 1 1 0 Divalent cation transporter Apq12 PF12716.7 GAN04737.1 - 0.48 10.4 11.5 0.87 9.6 11.5 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis CcmF_C PF16327.5 GAN04738.1 - 0.0038 16.6 0.2 0.0038 16.6 0.2 1.7 2 0 0 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal Sec66 PF09802.9 GAN04739.1 - 1.4e-46 158.4 2.9 1.4e-46 158.4 2.9 1.6 1 1 1 2 2 2 1 Preprotein translocase subunit Sec66 Neur_chan_memb PF02932.16 GAN04739.1 - 2.8 7.9 6.5 3.8 7.5 6.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 GAN04739.1 - 3.8 7.3 18.8 4.6 7.0 18.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 GAN04739.1 - 5.1 7.1 22.8 6.9 6.7 22.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.17 GAN04739.1 - 5.7 7.0 7.1 7.2 6.7 7.1 1.3 1 0 0 1 1 1 0 DDHD domain PIN_12 PF16289.5 GAN04739.1 - 9.8 6.6 11.8 6.9 7.1 10.3 1.5 1 1 1 2 2 2 0 PIN domain Pkinase PF00069.25 GAN04742.1 - 5.5e-57 193.1 0.0 8.6e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04742.1 - 6.1e-31 107.6 0.0 9.7e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAN04742.1 - 1.6e-07 31.9 3.5 6.2e-07 30.0 3.5 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 GAN04742.1 - 0.0002 21.0 0.0 0.16 11.6 0.1 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAN04742.1 - 0.0048 16.3 0.1 0.046 13.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PX PF00787.24 GAN04742.1 - 0.025 14.6 2.1 0.063 13.3 2.1 1.7 1 0 0 1 1 1 0 PX domain Peptidase_S28 PF05577.12 GAN04743.1 - 2.1e-68 231.1 2.2 2.5e-68 230.9 2.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 GAN04743.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BRE PF06113.12 GAN04744.1 - 7.5e-06 25.0 0.1 1.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Homeodomain PF00046.29 GAN04746.1 - 1.3e-17 63.3 3.0 4.4e-17 61.7 3.1 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 GAN04746.1 - 0.012 15.5 0.2 0.031 14.2 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF5606 PF18347.1 GAN04746.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5606) RRM_2 PF04059.12 GAN04747.1 - 6.8e-33 112.8 1.4 1.4e-32 111.7 1.4 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 BRAP2 PF07576.12 GAN04747.1 - 0.00093 19.4 0.2 0.0024 18.1 0.2 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 RRM_1 PF00076.22 GAN04747.1 - 0.0067 16.2 0.0 0.024 14.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 GAN04748.1 - 6.1e-23 81.2 0.3 1e-22 80.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PI3_PI4_kinase PF00454.27 GAN04749.1 - 8.3e-30 104.4 1.0 4.6e-28 98.7 0.0 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 GAN04749.1 - 2.9e-07 30.3 0.0 8e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 GAN04749.1 - 2.5e-05 23.8 0.1 5.4e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 GAN04749.1 - 0.016 14.6 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) FliG_M PF14841.6 GAN04749.1 - 0.16 12.2 1.0 0.34 11.1 1.0 1.6 1 0 0 1 1 1 0 FliG middle domain FAM176 PF14851.6 GAN04749.1 - 4.1 7.1 7.1 19 4.9 0.4 3.3 3 0 0 3 3 3 0 FAM176 family HSP70 PF00012.20 GAN04751.1 - 3e-259 861.3 10.6 3.4e-259 861.1 10.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN04751.1 - 1e-15 57.4 0.2 9.3e-15 54.3 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAN04751.1 - 0.012 15.4 0.0 0.061 13.0 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 GAN04751.1 - 0.015 14.8 0.0 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family SAPIS-gp6 PF16722.5 GAN04751.1 - 0.016 15.6 5.0 0.022 15.2 3.0 2.2 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Hydantoinase_A PF01968.18 GAN04751.1 - 0.018 14.3 0.2 0.018 14.3 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 GAN04751.1 - 0.04 13.1 0.9 0.089 12.0 0.0 1.9 2 0 0 2 2 2 0 StbA protein MutS_III PF05192.18 GAN04751.1 - 0.11 12.6 3.3 2 8.6 1.1 2.4 2 1 0 2 2 2 0 MutS domain III Prefoldin_2 PF01920.20 GAN04751.1 - 0.12 12.3 3.9 0.58 10.1 4.2 2.0 2 1 0 2 2 2 0 Prefoldin subunit ISG65-75 PF11727.8 GAN04751.1 - 3 7.0 11.5 3.5 6.8 9.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Glyco_H_20C_C PF18088.1 GAN04752.1 - 4.7e-48 163.6 4.1 8.8e-48 162.7 0.8 2.2 2 0 0 2 2 2 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 GAN04752.1 - 2.3e-12 47.0 0.3 1.1e-10 41.5 0.3 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain NAD_binding_10 PF13460.6 GAN04753.1 - 7e-15 55.4 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN04753.1 - 3.6e-14 52.9 0.2 6.1e-13 48.9 0.2 2.0 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 GAN04753.1 - 0.00024 20.6 0.0 0.0008 18.9 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 GAN04753.1 - 0.00079 19.0 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAN04753.1 - 0.019 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 GAN04753.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.24 GAN04753.1 - 0.034 14.6 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAN04753.1 - 0.071 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peripla_BP_6 PF13458.6 GAN04753.1 - 0.072 12.7 0.4 0.094 12.4 0.4 1.2 1 0 0 1 1 1 0 Periplasmic binding protein bPH_3 PF14470.6 GAN04753.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial PH domain Mit_KHE1 PF10173.9 GAN04754.1 - 7.3e-43 146.9 2.6 1.2e-42 146.1 2.6 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pkinase PF00069.25 GAN04755.1 - 3.2e-75 252.9 0.1 5.5e-75 252.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04755.1 - 3.4e-45 154.4 0.0 6.7e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04755.1 - 1.1e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN04755.1 - 2.3e-05 23.5 0.1 2.3e-05 23.5 0.1 2.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAN04755.1 - 0.00066 19.7 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN04755.1 - 0.01 15.2 0.6 0.019 14.3 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ntox14 PF15522.6 GAN04755.1 - 0.029 13.8 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Novel toxin 14 Choline_kinase PF01633.20 GAN04755.1 - 0.14 11.7 3.4 0.53 9.8 0.1 2.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase SUIM_assoc PF16619.5 GAN04755.1 - 3.3 7.9 17.9 0.12 12.4 6.5 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RAB3GAP2_N PF14655.6 GAN04755.1 - 4.2 6.5 11.2 0.24 10.6 5.3 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FAM176 PF14851.6 GAN04755.1 - 7.7 6.2 7.3 1.4 8.6 0.9 2.6 2 0 0 2 2 2 0 FAM176 family RNase_T PF00929.24 GAN04757.1 - 9.8e-11 42.5 0.1 2.2e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAN04757.1 - 5.9e-05 22.8 0.0 0.0024 17.6 0.0 3.2 2 1 0 2 2 2 1 3'-5' exonuclease zf-RING_UBOX PF13445.6 GAN04758.1 - 0.0041 17.1 12.6 0.0041 17.1 12.6 3.1 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAN04758.1 - 0.0049 17.0 12.6 0.0049 17.0 12.6 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAN04758.1 - 0.0049 16.7 16.2 0.0049 16.7 16.2 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) TMA7 PF09072.10 GAN04758.1 - 0.014 16.2 0.3 0.034 15.0 0.3 1.8 1 0 0 1 1 1 0 Translation machinery associated TMA7 zf-RING_6 PF14835.6 GAN04758.1 - 0.31 10.9 11.5 0.044 13.6 7.0 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 GAN04758.1 - 0.36 11.2 27.9 0.53 10.7 16.0 3.6 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 GAN04758.1 - 3.4 7.6 27.8 0.19 11.6 15.7 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN04758.1 - 3.8 7.5 25.2 2.1 8.4 16.5 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Rtf2 PF04641.12 GAN04758.1 - 3.9 6.8 11.4 1.6 8.0 8.1 2.0 2 1 0 2 2 2 0 Rtf2 RING-finger GATA PF00320.27 GAN04759.1 - 1.6e-16 59.6 4.6 3e-16 58.7 4.6 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-ribbon_3 PF13248.6 GAN04759.1 - 0.068 12.6 2.1 1 8.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 GAN04759.1 - 0.14 12.0 3.5 1.7 8.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain FAM163 PF15069.6 GAN04759.1 - 4.4 7.7 6.2 0.4 11.1 0.3 2.3 3 0 0 3 3 3 0 FAM163 family TFIIA PF03153.13 GAN04759.1 - 6 6.8 21.2 2.7 7.9 18.9 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M61_N PF17899.1 GAN04760.1 - 0.021 14.9 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase M61 N-terminal domain YscW PF09619.10 GAN04760.1 - 0.083 13.3 0.1 4.3 7.7 0.0 2.9 1 1 1 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) DUF2052 PF09747.9 GAN04760.1 - 0.59 10.2 10.2 1.1 9.3 10.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4391 PF14335.6 GAN04760.1 - 2.4 7.8 5.4 3.3 7.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4391) DUF4097 PF13349.6 GAN04761.1 - 1e-08 34.8 13.2 1.1e-06 28.2 13.2 2.8 1 1 0 1 1 1 1 Putative adhesin DUF4313 PF14190.6 GAN04761.1 - 0.0021 18.0 0.1 0.0058 16.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4313) FYRN PF05964.14 GAN04762.1 - 1.3e-17 63.4 0.8 3.2e-17 62.1 0.5 1.9 2 0 0 2 2 2 1 F/Y-rich N-terminus FYRC PF05965.14 GAN04762.1 - 2.1e-16 59.9 0.0 4.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus Laminin_II PF06009.12 GAN04762.1 - 0.067 13.2 0.7 0.15 12.0 0.4 1.6 1 1 0 1 1 1 0 Laminin Domain II O-FucT PF10250.9 GAN04763.1 - 1.5e-19 70.9 0.0 5.7e-11 42.7 0.0 3.5 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase LON_substr_bdg PF02190.16 GAN04764.1 - 1.5e-16 60.9 0.0 4.7e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF410 PF04190.13 GAN04765.1 - 3.7e-76 256.3 0.0 4.6e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Ank_4 PF13637.6 GAN04766.1 - 2.9e-21 75.5 4.4 2.4e-09 37.5 0.1 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN04766.1 - 5.7e-17 62.1 0.5 8.3e-08 32.7 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN04766.1 - 3.3e-15 54.7 4.3 1.9e-07 30.8 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 GAN04766.1 - 1.7e-14 53.5 8.4 3e-07 30.6 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAN04766.1 - 9.6e-14 51.3 2.0 4.9e-08 33.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DNA_mis_repair PF01119.19 GAN04767.1 - 2.9e-12 46.3 2.0 7.5e-10 38.5 2.0 2.9 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAN04767.1 - 3e-10 40.1 0.2 3e-10 40.1 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAN04767.1 - 0.0012 19.4 0.1 0.0029 18.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KH_8 PF17903.1 GAN04767.1 - 0.06 13.4 0.1 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Krr1 KH1 domain CotH PF08757.11 GAN04768.1 - 7.4e-38 130.9 5.7 1.1e-37 130.3 5.7 1.2 1 0 0 1 1 1 1 CotH kinase protein Med10 PF09748.9 GAN04769.1 - 2.6e-30 104.9 0.0 3.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex NAAA-beta PF15508.6 GAN04769.1 - 0.1 12.9 0.1 0.45 10.8 0.0 2.0 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase VCBS PF13517.6 GAN04770.1 - 0.00055 20.5 0.3 0.0083 16.7 0.0 2.7 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 GAN04770.1 - 0.0074 16.3 0.0 1.7 8.8 0.0 3.2 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 GAN04770.1 - 0.059 12.4 0.0 9.7 5.1 0.0 2.7 2 1 1 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 GAN04770.1 - 0.077 13.1 0.0 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 FG-GAP repeat PI3_PI4_kinase PF00454.27 GAN04771.1 - 4.9e-49 167.4 0.0 2.3e-48 165.2 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SR-25 PF10500.9 GAN04771.1 - 0.0034 17.0 4.4 0.0034 17.0 4.4 3.8 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein LAT PF15234.6 GAN04771.1 - 0.017 14.8 1.0 0.017 14.8 1.0 3.0 4 0 0 4 4 4 0 Linker for activation of T-cells Macoilin PF09726.9 GAN04771.1 - 0.06 11.9 4.2 0.14 10.6 4.2 1.6 1 0 0 1 1 1 0 Macoilin family Peptidase_U4 PF03419.13 GAN04772.1 - 0.0074 15.6 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Sporulation factor SpoIIGA p450 PF00067.22 GAN04773.1 - 4.6e-72 243.2 0.0 6e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5009 PF16401.5 GAN04773.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) DUF3759 PF12585.8 GAN04774.1 - 2.8e-16 59.3 10.9 6.4e-16 58.2 10.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.6 GAN04774.1 - 0.036 14.8 0.0 0.91 10.3 0.0 2.5 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Aminotran_3 PF00202.21 GAN04775.1 - 3.4e-118 394.9 0.0 4.3e-118 394.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Serine_rich PF08824.10 GAN04775.1 - 0.028 14.4 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain CN_hydrolase PF00795.22 GAN04776.1 - 2.1e-35 122.3 0.0 2.5e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PPTA PF01239.22 GAN04777.1 - 7.6e-43 143.1 17.8 1.3e-09 37.5 0.2 6.3 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat FOP_dimer PF09398.10 GAN04777.1 - 0.046 14.0 0.0 2 8.8 0.0 3.0 2 1 1 3 3 3 0 FOP N terminal dimerisation domain Torus PF16131.5 GAN04778.1 - 5.4e-33 113.9 0.2 5.4e-33 113.9 0.2 2.2 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 GAN04778.1 - 8.8e-09 35.1 0.0 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAN04778.1 - 0.00087 19.3 1.5 0.0015 18.5 1.5 1.4 1 0 0 1 1 1 1 Zinc finger domain DUF4536 PF15055.6 GAN04779.1 - 1.8e-05 24.9 5.7 0.00027 21.1 0.9 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4536) DUF5516 PF17637.2 GAN04779.1 - 0.024 14.4 1.1 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Cytochrome_C554 PF13435.6 GAN04779.1 - 0.14 13.1 0.0 0.15 13.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime DUF4597 PF15366.6 GAN04779.1 - 0.18 11.6 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) DUF1328 PF07043.13 GAN04779.1 - 3.6 7.9 7.0 2.3 8.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) Peptidase_A22B PF04258.13 GAN04780.1 - 3.8e-51 174.3 13.2 5.2e-51 173.9 13.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Corona_nucleoca PF00937.18 GAN04780.1 - 4.4 6.2 14.5 4 6.4 3.1 2.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Carboxyl_trans PF01039.22 GAN04781.1 - 8e-188 625.1 0.0 9.3e-188 624.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 GAN04781.1 - 0.00086 18.9 1.2 0.0066 16.0 0.0 2.5 2 1 1 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Questin_oxidase PF14027.6 GAN04783.1 - 8.6e-33 114.3 0.1 1.1e-32 113.9 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like BLOC1_2 PF10046.9 GAN04784.1 - 6.4e-05 23.2 11.1 0.052 13.8 0.4 3.4 2 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 GAN04784.1 - 0.0012 18.9 0.6 0.14 12.2 0.0 2.6 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 GAN04784.1 - 0.0059 16.4 12.1 0.044 13.6 0.2 3.2 2 1 1 3 3 3 1 CdvA-like coiled-coil domain JAKMIP_CC3 PF16034.5 GAN04784.1 - 0.0094 15.9 15.6 0.13 12.2 0.5 2.5 1 1 1 2 2 2 2 JAKMIP CC3 domain GCR PF02155.15 GAN04784.1 - 0.012 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Glucocorticoid receptor DUF1319 PF07028.11 GAN04784.1 - 0.013 15.7 6.4 3.4 7.9 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) DUF1664 PF07889.12 GAN04784.1 - 0.016 15.3 7.7 0.19 11.8 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAN04784.1 - 0.025 14.8 14.5 0.14 12.3 0.8 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family CCDC144C PF14915.6 GAN04784.1 - 0.027 13.6 11.7 0.11 11.6 3.0 2.5 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region CREPT PF16566.5 GAN04784.1 - 0.031 14.5 4.8 0.062 13.5 0.4 2.3 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4635 PF15466.6 GAN04784.1 - 0.055 13.0 3.8 1.3 8.5 0.3 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4635) Phage_GPO PF05929.11 GAN04784.1 - 0.08 12.6 8.8 0.44 10.1 1.0 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Surfac_D-trimer PF09006.11 GAN04784.1 - 0.15 12.0 1.2 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Mt_ATP-synt_D PF05873.12 GAN04784.1 - 0.17 11.7 11.1 6.9 6.5 5.7 3.0 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Sec2p PF06428.11 GAN04784.1 - 0.19 11.7 8.7 0.98 9.4 0.1 3.0 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.11 GAN04784.1 - 0.21 11.9 10.2 0.66 10.2 1.6 3.3 2 1 0 3 3 3 0 Spc24 subunit of Ndc80 Helo_like_N PF17111.5 GAN04784.1 - 0.22 10.9 9.6 1.2 8.5 2.2 2.1 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF948 PF06103.11 GAN04784.1 - 0.28 11.4 2.7 20 5.6 0.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Bap31_Bap29_C PF18035.1 GAN04784.1 - 0.3 11.1 4.3 0.28 11.2 1.8 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain OmpH PF03938.14 GAN04784.1 - 0.31 11.4 16.0 4.3 7.7 8.8 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 GAN04784.1 - 0.32 11.6 12.9 9.4 6.9 0.5 3.7 2 1 1 3 3 3 0 SlyX FlaC_arch PF05377.11 GAN04784.1 - 0.39 11.1 7.1 21 5.6 0.1 4.5 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Plk4_PB2 PF18409.1 GAN04784.1 - 0.5 11.1 5.6 10 6.8 0.7 2.9 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 CENP-F_leu_zip PF10473.9 GAN04784.1 - 0.62 10.1 11.8 0.46 10.5 1.2 3.0 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ax_dynein_light PF10211.9 GAN04784.1 - 0.7 9.8 16.2 0.31 10.9 2.3 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain GAS PF13851.6 GAN04784.1 - 0.7 9.2 15.9 0.86 8.9 12.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FliD_C PF07195.12 GAN04784.1 - 0.88 8.9 11.9 3.9 6.8 0.7 3.3 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.9 GAN04784.1 - 1.2 8.1 16.5 4.6 6.2 4.8 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 GAN04784.1 - 1.6 9.2 18.8 0.14 12.6 6.8 3.6 2 1 0 2 2 2 0 Cell division protein ZapB Nbs1_C PF08599.10 GAN04784.1 - 2.1 8.5 6.0 0.32 11.2 1.1 2.1 2 0 0 2 2 1 0 DNA damage repair protein Nbs1 DUF16 PF01519.16 GAN04784.1 - 2.5 8.6 10.2 4.3 7.9 0.9 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 FAM76 PF16046.5 GAN04784.1 - 2.5 7.4 12.4 16 4.7 12.4 2.0 1 1 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 GAN04784.1 - 4.7 6.4 17.8 0.82 8.9 0.8 3.0 1 1 2 3 3 3 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 GAN04784.1 - 5.1 7.3 16.1 1.3 9.2 0.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.20 GAN04784.1 - 6.7 6.7 16.3 12 5.9 3.8 3.8 3 1 1 4 4 4 0 Prefoldin subunit APG6_N PF17675.1 GAN04784.1 - 9.6 6.7 17.4 0.59 10.7 2.7 3.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Pkinase PF00069.25 GAN04785.1 - 1.1e-52 179.0 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04785.1 - 1e-36 126.6 0.0 1.5e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN04785.1 - 7.7e-06 24.9 0.1 2.6e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN04785.1 - 0.00062 19.2 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GAN04785.1 - 0.05 13.2 0.0 0.27 10.8 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 GAN04785.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2461 PF09365.10 GAN04786.1 - 1.5e-61 208.0 0.2 1.5e-61 208.0 0.2 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) DUF2478 PF10649.9 GAN04786.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Cwf_Cwc_15 PF04889.12 GAN04786.1 - 0.35 10.6 28.3 0.73 9.5 28.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Red1 PF07964.11 GAN04786.1 - 5.3 5.1 31.8 7.3 4.7 31.8 1.1 1 0 0 1 1 1 0 Rec10 / Red1 CDK5_activator PF03261.15 GAN04786.1 - 6.1 6.3 11.8 9.7 5.6 11.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein ERCC3_RAD25_C PF16203.5 GAN04787.1 - 9.2e-65 218.3 0.1 2.7e-38 131.6 0.1 2.4 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAN04787.1 - 3.7e-21 75.9 0.0 8.8e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN04787.1 - 5e-10 39.7 0.4 1.1e-08 35.4 0.1 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GAN04787.1 - 7.1e-10 38.1 0.0 1.7e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 GAN04787.1 - 1.6e-05 24.8 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAN04787.1 - 8.7e-05 22.3 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 GAN04787.1 - 0.0015 17.5 0.0 0.0032 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 EGF_Tenascin PF18720.1 GAN04788.1 - 0.23 11.5 2.7 0.5 10.5 2.7 1.5 1 0 0 1 1 1 0 Tenascin EGF domain CRCB PF02537.15 GAN04788.1 - 0.98 9.8 8.6 0.63 10.4 4.9 2.5 1 1 1 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) AcrZ PF10766.9 GAN04788.1 - 2.4 7.8 8.0 1.1 8.9 4.5 2.2 1 1 1 2 2 2 0 Multidrug efflux pump-associated protein AcrZ UPF0182 PF03699.13 GAN04788.1 - 3.5 5.6 10.2 5.6 5.0 10.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) PFK PF00365.20 GAN04789.1 - 2.7e-193 640.5 5.4 6.1e-107 357.2 0.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 GAN04789.1 - 0.02 15.3 0.1 0.038 14.4 0.1 1.4 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 GAN04789.1 - 0.028 14.0 0.5 0.15 11.6 0.2 2.5 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Peptidase_M19 PF01244.21 GAN04789.1 - 0.049 12.8 0.1 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) HECT PF00632.25 GAN04790.1 - 6.9e-88 295.1 1.5 7.1e-88 295.0 0.2 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Peptidase_C58 PF03543.14 GAN04790.1 - 0.09 12.5 0.6 0.19 11.4 0.6 1.5 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Mito_carr PF00153.27 GAN04791.1 - 2.1e-65 216.7 4.3 8.6e-24 83.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 GAN04792.1 - 4.7e-65 219.6 0.0 2.5e-35 122.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04792.1 - 1.5e-25 90.0 0.3 5.1e-16 58.7 0.1 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN04792.1 - 0.00025 20.5 0.3 0.35 10.1 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Myb_DNA-binding PF00249.31 GAN04793.1 - 1.7e-21 76.1 0.5 6.6e-09 35.8 0.1 3.9 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN04793.1 - 5.6e-09 36.1 8.0 0.00014 22.1 0.5 3.9 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAN04793.1 - 2.9e-07 30.3 9.0 0.0026 17.6 0.9 4.0 3 0 0 3 3 3 2 Myb DNA-binding like DUF883 PF05957.13 GAN04793.1 - 6.1 7.5 7.6 48 4.6 7.6 2.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Cg6151-P PF10233.9 GAN04794.1 - 4.6e-25 88.1 11.4 8.1e-25 87.3 11.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Fer4_20 PF14691.6 GAN04794.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF373 PF04123.13 GAN04794.1 - 0.18 11.2 4.4 0.23 10.9 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) PRA1 PF03208.19 GAN04794.1 - 1.5 8.5 16.8 0.068 12.8 4.0 2.1 1 1 1 2 2 2 0 PRA1 family protein Tropomyosin_1 PF12718.7 GAN04795.1 - 5.5e-16 59.0 19.6 5.4e-11 42.8 9.5 2.0 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 GAN04795.1 - 1.6e-05 24.4 23.1 1.7e-05 24.3 23.1 1.0 1 0 0 1 1 1 1 Tropomyosin SHE3 PF17078.5 GAN04795.1 - 0.0035 17.1 14.4 0.7 9.6 14.4 2.1 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 VGPC1_C PF16799.5 GAN04795.1 - 0.0056 16.6 2.8 0.69 9.9 0.1 2.4 2 0 0 2 2 2 1 C-terminal membrane-localisation domain of ion-channel, VCN1 FPP PF05911.11 GAN04795.1 - 0.0062 14.8 17.3 0.0071 14.6 17.3 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF724 PF05266.14 GAN04795.1 - 0.01 15.7 7.1 0.01 15.7 7.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.13 GAN04795.1 - 0.013 15.9 13.0 0.013 15.9 13.0 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 GAN04795.1 - 0.014 15.0 16.1 0.017 14.7 15.8 1.2 1 1 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 GAN04795.1 - 0.016 15.7 11.9 0.016 15.7 11.9 1.7 1 1 1 2 2 2 0 Fez1 Alanine_zipper PF11839.8 GAN04795.1 - 0.026 14.9 1.6 0.026 14.9 1.6 2.5 2 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF2895 PF11444.8 GAN04795.1 - 0.057 12.8 1.7 0.072 12.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) GAS PF13851.6 GAN04795.1 - 0.06 12.7 20.7 0.69 9.2 20.7 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 GAN04795.1 - 0.064 13.7 6.4 2.2 8.7 2.2 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4472 PF14739.6 GAN04795.1 - 0.066 13.9 14.4 0.19 12.5 12.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) YjbH PF06082.11 GAN04795.1 - 0.073 11.9 2.8 0.08 11.7 2.8 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH TPR_MLP1_2 PF07926.12 GAN04795.1 - 0.093 12.8 23.4 0.27 11.3 23.0 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein KH_10 PF17905.1 GAN04795.1 - 0.098 13.1 0.5 0.14 12.6 0.5 1.3 1 1 0 1 1 1 0 GLD-3 KH domain 5 DUF4315 PF14193.6 GAN04795.1 - 0.1 12.6 14.2 0.16 12.0 2.4 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4315) Laminin_II PF06009.12 GAN04795.1 - 0.12 12.4 9.7 0.12 12.4 4.9 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF489 PF04356.12 GAN04795.1 - 0.15 12.0 5.5 1.2 9.1 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Jnk-SapK_ap_N PF09744.9 GAN04795.1 - 0.19 12.0 20.0 0.26 11.5 20.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 GAN04795.1 - 0.2 12.2 26.6 2.4 8.7 26.6 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Tup_N PF08581.10 GAN04795.1 - 0.2 12.0 15.9 0.41 11.0 4.7 2.2 1 1 1 2 2 2 0 Tup N-terminal CENP-F_leu_zip PF10473.9 GAN04795.1 - 0.25 11.3 21.0 2.6 8.1 6.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4094 PF13334.6 GAN04795.1 - 0.32 11.4 4.5 0.62 10.5 4.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3450 PF11932.8 GAN04795.1 - 0.34 10.2 17.4 0.31 10.3 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AKNA PF12443.8 GAN04795.1 - 0.37 11.5 7.1 1.1 10.0 2.2 2.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor CLZ PF16526.5 GAN04795.1 - 0.42 11.0 15.3 1.1 9.7 3.4 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 GAN04795.1 - 0.45 10.7 19.3 0.73 10.0 19.3 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 GAN04795.1 - 0.52 10.5 16.8 3.4 7.9 16.4 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LemA PF04011.12 GAN04795.1 - 0.58 10.0 9.0 4.8 7.0 3.3 2.5 1 1 1 2 2 2 0 LemA family WXG100 PF06013.12 GAN04795.1 - 0.61 10.4 7.4 1.7 8.9 0.2 3.1 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 GAN04795.1 - 0.61 10.1 5.3 9.9 6.2 1.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 GAN04795.1 - 0.71 10.2 13.3 0.74 10.2 4.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) XhlA PF10779.9 GAN04795.1 - 0.72 10.1 13.7 0.14 12.4 3.3 2.9 2 1 1 3 3 3 0 Haemolysin XhlA AAA_13 PF13166.6 GAN04795.1 - 0.78 8.3 12.5 0.83 8.2 12.5 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 GAN04795.1 - 0.81 8.9 9.7 0.92 8.7 9.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 GAN04795.1 - 0.84 8.9 13.7 1 8.7 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAN04795.1 - 0.93 8.3 20.9 1.9 7.3 20.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 GAN04795.1 - 1.1 9.8 14.2 0.31 11.5 2.9 3.3 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Mod_r PF07200.13 GAN04795.1 - 1.5 9.0 19.2 35 4.5 19.2 2.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF812 PF05667.11 GAN04795.1 - 1.5 7.6 17.5 1.9 7.3 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 GAN04795.1 - 1.5 8.9 17.5 1.8 8.6 10.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 GAN04795.1 - 1.7 8.9 8.6 1.5 9.0 5.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Hrs_helical PF12210.8 GAN04795.1 - 2.4 8.7 11.5 4.6 7.8 2.0 2.5 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UPF0242 PF06785.11 GAN04795.1 - 2.6 8.1 17.8 3.3 7.8 17.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 GAN04795.1 - 3 8.5 14.6 0.23 12.1 1.3 3.1 1 1 2 3 3 3 0 SlyX DUF745 PF05335.13 GAN04795.1 - 3.3 7.4 17.6 1.8 8.3 11.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) OmpH PF03938.14 GAN04795.1 - 3.6 7.9 21.2 1.6e+02 2.6 21.2 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Med4 PF10018.9 GAN04795.1 - 4.4 6.9 14.2 34 4.1 12.7 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4337 PF14235.6 GAN04795.1 - 4.8 7.3 18.4 5.6 7.1 7.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Fmp27_WPPW PF10359.9 GAN04795.1 - 6.4 5.5 10.8 8.2 5.1 10.8 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2203 PF09969.9 GAN04795.1 - 7.1 7.4 12.0 26 5.5 1.7 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HAUS-augmin3 PF14932.6 GAN04795.1 - 7.3 6.1 19.1 12 5.4 17.1 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 ERM PF00769.19 GAN04795.1 - 8.2 6.2 24.1 10 5.9 24.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LMBR1 PF04791.16 GAN04795.1 - 10 4.9 9.2 17 4.1 9.2 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein RSN1_7TM PF02714.15 GAN04796.1 - 1.7e-45 155.5 19.7 4.4e-45 154.1 19.7 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAN04796.1 - 3.1e-26 92.7 2.9 7.8e-26 91.4 0.7 2.2 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAN04796.1 - 4.8e-25 88.1 4.7 4.8e-25 88.1 4.7 4.9 5 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport F-box-like PF12937.7 GAN04797.1 - 3.2e-05 23.7 0.0 6.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04797.1 - 0.039 13.8 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.7 GAN04797.1 - 0.85 10.1 4.2 43 4.7 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ferric_reduct PF01794.19 GAN04798.1 - 5.5e-19 68.5 4.6 5.5e-19 68.5 4.6 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAN04798.1 - 3.1e-10 40.4 0.0 7.3e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAN04798.1 - 9.4e-06 25.7 0.1 0.0002 21.4 0.1 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAN04798.1 - 0.0066 17.1 0.0 0.018 15.7 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain PLDc_2 PF13091.6 GAN04800.1 - 1.3e-26 93.1 0.1 2e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 GAN04800.1 - 0.0021 17.6 9.7 0.0087 15.6 1.7 3.0 2 1 0 2 2 2 1 FAM83 A-H PLDc PF00614.22 GAN04800.1 - 0.016 15.3 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 Phospholipase D Active site motif Ribosomal_60s PF00428.19 GAN04800.1 - 0.052 14.1 1.5 2.4 8.8 0.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Zn-C2H2_12 PF18112.1 GAN04801.1 - 0.19 12.2 0.8 0.38 11.3 0.8 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain HLH PF00010.26 GAN04802.1 - 5.1e-20 71.2 0.4 5.1e-20 71.2 0.4 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_S9 PF00380.19 GAN04802.1 - 0.063 13.8 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DUF2878 PF11086.8 GAN04805.1 - 0.0044 17.2 0.6 0.0044 17.2 0.6 3.6 4 1 1 5 5 5 1 Protein of unknown function (DUF2878) Septin PF00735.18 GAN04806.1 - 1.7e-110 368.8 2.2 3.1e-110 367.9 0.8 2.3 2 0 0 2 2 2 1 Septin SMC_N PF02463.19 GAN04806.1 - 1.7e-57 194.4 37.5 5.5e-56 189.4 35.2 3.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAN04806.1 - 4.6e-27 94.7 0.0 2.1e-26 92.5 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAN04806.1 - 2e-16 60.7 0.2 5.7e-08 32.9 0.1 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAN04806.1 - 7.3e-11 41.7 0.0 5.9e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAN04806.1 - 1.8e-09 37.7 5.5 2e-08 34.3 0.2 4.3 4 1 0 4 4 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN04806.1 - 9.7e-06 25.6 0.5 9.7e-06 25.6 0.5 4.5 4 0 0 4 4 4 1 RsgA GTPase AIG1 PF04548.16 GAN04806.1 - 6.6e-05 22.3 0.0 6.6e-05 22.3 0.0 3.4 3 1 0 3 3 2 1 AIG1 family ABC_tran PF00005.27 GAN04806.1 - 0.00019 22.0 24.0 0.033 14.7 0.0 6.4 5 2 0 5 5 3 2 ABC transporter Roc PF08477.13 GAN04806.1 - 0.0015 18.7 0.2 0.02 15.1 0.1 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Spc7 PF08317.11 GAN04806.1 - 0.0023 16.9 5.5 0.0023 16.9 5.5 6.2 5 1 1 6 6 6 1 Spc7 kinetochore protein GTP_EFTU PF00009.27 GAN04806.1 - 0.0026 17.3 0.1 0.0026 17.3 0.1 4.1 4 1 0 4 4 3 1 Elongation factor Tu GTP binding domain BRE1 PF08647.11 GAN04806.1 - 0.0038 17.3 0.3 0.0038 17.3 0.3 8.9 7 3 1 8 8 6 1 BRE1 E3 ubiquitin ligase AAA_33 PF13671.6 GAN04806.1 - 0.0038 17.4 0.0 7.5 6.7 0.0 3.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAN04806.1 - 0.0038 16.8 0.2 0.039 13.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 GAN04806.1 - 0.0042 17.6 107.9 15 6.0 3.1 7.7 3 2 0 5 5 4 0 AAA domain RNA_helicase PF00910.22 GAN04806.1 - 0.0043 17.4 0.1 2.8 8.4 0.0 3.4 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.18 GAN04806.1 - 0.0061 15.9 2.9 0.0065 15.9 0.1 2.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.6 GAN04806.1 - 0.0072 16.7 9.4 0.042 14.2 0.0 5.0 5 0 0 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 GAN04806.1 - 0.01 16.1 10.2 0.1 12.9 0.0 5.3 5 1 1 6 6 5 0 AAA domain SbcCD_C PF13558.6 GAN04806.1 - 0.014 15.6 0.0 0.057 13.6 0.0 2.1 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ras PF00071.22 GAN04806.1 - 0.018 14.6 0.7 0.17 11.5 0.1 3.1 3 0 0 3 3 2 0 Ras family AAA_5 PF07728.14 GAN04806.1 - 0.053 13.5 4.0 4.9 7.2 0.0 4.5 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 GAN04806.1 - 0.33 11.0 0.0 0.33 11.0 0.0 6.7 4 2 1 5 5 2 0 Helicase HerA, central domain AAA_14 PF13173.6 GAN04806.1 - 0.65 10.0 4.5 2.8 8.0 0.0 4.1 4 0 0 4 4 3 0 AAA domain zf-ZPR1 PF03367.13 GAN04807.1 - 1.2e-112 373.0 0.2 4.5e-55 185.9 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 GAN04807.1 - 0.2 11.7 5.8 0.57 10.2 1.2 2.5 2 1 0 2 2 2 0 zinc-ribbons Lar_restr_allev PF14354.6 GAN04807.1 - 0.2 12.1 3.5 19 5.7 1.2 2.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar CpXC PF14353.6 GAN04807.1 - 0.25 11.4 5.5 2.8 8.0 0.0 3.3 2 1 0 2 2 2 0 CpXC protein UPF0547 PF10571.9 GAN04807.1 - 0.47 10.6 8.7 1.5 9.0 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.16 GAN04807.1 - 7.1 6.6 7.4 12 5.8 4.4 2.7 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Pkinase PF00069.25 GAN04808.1 - 5.5e-20 71.8 0.2 9.9e-20 71.0 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04808.1 - 5.3e-06 25.9 0.0 8.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4064 PF13273.6 GAN04808.1 - 0.14 12.5 1.2 0.37 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) CTD_bind PF04818.13 GAN04808.1 - 0.21 12.4 0.6 0.71 10.7 0.3 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Rax2 PF12768.7 GAN04809.1 - 1e-27 97.1 0.5 1e-27 97.1 0.5 4.0 5 0 0 5 5 5 1 Cortical protein marker for cell polarity SH3_9 PF14604.6 GAN04809.1 - 1.2e-09 37.8 0.1 3.4e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN04809.1 - 5.8e-07 29.0 0.1 1.4e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN04809.1 - 1.4e-05 24.7 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF5122 PF17164.4 GAN04809.1 - 0.076 13.3 4.4 31 5.0 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller WD40 PF00400.32 GAN04809.1 - 0.087 13.7 0.1 0.98 10.4 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Kelch_2 PF07646.15 GAN04809.1 - 0.11 12.5 0.8 1.5e+02 2.6 0.0 4.6 5 0 0 5 5 5 0 Kelch motif RhoGAP PF00620.27 GAN04810.1 - 1.3e-46 158.2 1.2 1.5e-46 158.0 0.2 1.6 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.28 GAN04810.1 - 7.1e-15 54.3 1.6 1.7e-14 53.2 1.6 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN04810.1 - 1.8e-10 40.5 0.2 3.4e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN04810.1 - 3.5e-09 36.2 0.0 7.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 GAN04810.1 - 2.8e-05 24.6 0.0 8.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF1708 PF08101.11 GAN04810.1 - 0.0028 16.9 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGEF PF00621.20 GAN04811.1 - 3.8e-35 121.8 0.9 1.3e-34 120.0 0.9 2.0 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAN04811.1 - 3e-05 24.5 0.1 3e-05 24.5 0.1 3.1 4 0 0 4 4 4 1 PH domain PH_6 PF15406.6 GAN04811.1 - 0.024 14.9 0.1 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 GAN04811.1 - 0.039 13.8 1.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3808 PF10300.9 GAN04812.1 - 5.3e-74 249.7 9.5 7e-56 189.9 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) TPR_2 PF07719.17 GAN04812.1 - 0.013 15.5 3.5 1.5 9.1 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN04812.1 - 0.92 10.3 5.1 7.2 7.5 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Metallophos PF00149.28 GAN04813.1 - 4.7e-34 118.7 0.2 7.8e-34 118.0 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN04813.1 - 0.00044 20.6 0.3 0.00097 19.5 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 GAN04813.1 - 0.041 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CCDC74_C PF14917.6 GAN04814.1 - 0.42 11.1 3.9 0.46 11.0 0.5 2.2 1 1 1 2 2 2 0 Coiled coil protein 74, C terminal Pkinase_Tyr PF07714.17 GAN04816.1 - 2.7e-30 105.5 0.6 8.6e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAN04816.1 - 7.4e-23 81.3 2.1 2.5e-15 56.6 0.8 2.7 2 1 0 2 2 2 2 Protein kinase domain SAP PF02037.27 GAN04816.1 - 4.5e-05 23.1 0.1 9e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 GAN04816.1 - 0.0035 16.7 0.2 0.0054 16.1 0.2 1.2 1 0 0 1 1 1 1 LETM1-like protein Pyr_redox_2 PF07992.14 GAN04817.1 - 9.5e-33 113.7 0.2 1.2e-32 113.3 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN04817.1 - 4.7e-14 52.7 1.6 3.1e-09 37.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN04817.1 - 2.9e-09 36.6 1.6 7.5e-08 32.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN04817.1 - 2.8e-07 30.6 1.6 0.014 15.4 0.1 4.1 3 1 0 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAN04817.1 - 1.3e-06 27.6 0.8 0.0013 17.7 0.2 3.2 4 0 0 4 4 4 2 Tryptophan halogenase DAO PF01266.24 GAN04817.1 - 1.1e-05 25.2 0.4 0.038 13.6 0.5 2.8 2 2 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAN04817.1 - 1.5e-05 24.3 0.1 0.00034 19.9 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 GAN04817.1 - 2.2e-05 24.7 0.3 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_8 PF13450.6 GAN04817.1 - 0.00049 20.3 0.2 0.025 14.8 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 GAN04817.1 - 0.0013 19.2 0.2 0.039 14.4 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAN04817.1 - 0.0027 16.8 0.0 1.9 7.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 GAN04817.1 - 0.0028 17.9 0.9 2.3 8.5 0.0 3.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 GAN04817.1 - 0.041 13.4 0.2 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) GFO_IDH_MocA PF01408.22 GAN04817.1 - 0.062 14.1 0.1 11 6.9 0.0 2.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Thi4 PF01946.17 GAN04817.1 - 0.1 11.8 1.6 8.7 5.5 0.0 2.9 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 GAN04817.1 - 0.11 11.7 0.1 7.5 5.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 GAN04817.1 - 0.22 10.5 0.9 4.8 6.2 0.5 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Aminotran_5 PF00266.19 GAN04818.1 - 1e-27 97.1 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 GAN04818.1 - 0.002 18.1 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain KR PF08659.10 GAN04818.1 - 0.03 14.2 0.5 0.061 13.2 0.0 1.7 2 0 0 2 2 2 0 KR domain START PF01852.19 GAN04819.1 - 2.3e-19 69.7 0.0 2.8e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 START domain MAPEG PF01124.18 GAN04820.1 - 0.00049 20.0 6.5 0.0014 18.6 6.6 1.7 1 1 1 2 2 2 1 MAPEG family LRR_8 PF13855.6 GAN04821.1 - 2.8e-15 55.8 17.9 1.7e-07 30.9 2.3 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAN04821.1 - 2.6e-09 37.2 22.6 0.00069 20.0 2.5 4.1 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN04821.1 - 0.015 15.7 11.6 10 7.1 0.0 5.8 5 0 0 5 5 5 0 Leucine Rich Repeat Hira PF07569.11 GAN04822.1 - 2.6e-62 210.4 0.4 2.6e-62 210.4 0.4 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 GAN04822.1 - 1.8e-28 98.2 16.0 1.2e-06 29.1 0.9 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN04822.1 - 4.2e-15 55.8 1.6 0.023 15.0 0.1 6.6 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 GAN04822.1 - 2.2e-10 40.1 1.2 8.5e-10 38.3 1.2 2.1 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 GAN04822.1 - 0.00082 18.4 0.3 0.49 9.3 0.0 4.0 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAN04822.1 - 0.096 12.7 2.1 20 5.2 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PRKCSH PF07915.13 GAN04823.1 - 2.3e-14 54.1 2.7 2.3e-14 54.1 2.7 3.0 4 0 0 4 4 4 1 Glucosidase II beta subunit-like protein Serine_protease PF18405.1 GAN04823.1 - 0.12 11.5 0.1 0.3 10.2 0.1 1.6 1 0 0 1 1 1 0 Gammaproteobacterial serine protease DUF1690 PF07956.11 GAN04824.1 - 9.3e-31 107.1 11.8 1.1e-30 106.9 11.8 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) MCM_lid PF17855.1 GAN04824.1 - 0.0031 17.9 3.9 0.1 13.0 0.4 2.3 1 1 1 2 2 2 2 MCM AAA-lid domain Pinin_SDK_memA PF04696.13 GAN04824.1 - 0.23 11.5 8.2 0.4 10.7 8.2 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region ORF6N PF10543.9 GAN04824.1 - 1.1 9.5 6.2 0.25 11.6 1.3 2.2 2 1 0 2 2 2 0 ORF6N domain GATA PF00320.27 GAN04825.1 - 1.3e-29 101.5 15.2 1.3e-15 56.7 4.0 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 GAN04825.1 - 1.8e-11 43.7 2.3 1.8e-11 43.7 2.3 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 GAN04825.1 - 0.00011 22.3 1.5 0.22 11.7 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 GAN04825.1 - 0.001 18.5 6.2 0.13 11.8 0.6 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding FYVE PF01363.21 GAN04825.1 - 0.21 11.7 3.1 2.7 8.2 0.2 3.2 3 0 0 3 3 3 0 FYVE zinc finger Auto_anti-p27 PF06677.12 GAN04825.1 - 0.27 11.4 5.4 8 6.7 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) FliP PF00813.20 GAN04825.1 - 0.28 11.1 4.6 0.69 9.8 4.6 1.6 1 0 0 1 1 1 0 FliP family Vps36-NZF-N PF16988.5 GAN04825.1 - 0.34 10.3 8.6 4 6.9 0.3 4.0 2 2 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 GAN04825.1 - 0.35 10.9 9.0 13 5.9 9.7 2.8 1 1 1 2 2 2 0 Double zinc ribbon zf-B_box PF00643.24 GAN04825.1 - 0.43 10.8 5.9 23 5.3 0.0 3.8 4 0 0 4 4 4 0 B-box zinc finger DUF2813 PF11398.8 GAN04825.1 - 0.66 9.2 16.6 1.4 8.1 16.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) GvpL_GvpF PF06386.11 GAN04825.1 - 1.4 8.8 8.6 2.6 7.9 8.6 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF XRN_M PF17846.1 GAN04825.1 - 3 6.7 10.1 0.53 9.2 6.2 1.7 2 0 0 2 2 2 0 Xrn1 helical domain DUF2064 PF09837.9 GAN04825.1 - 5.5 6.8 9.9 13 5.6 9.9 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) ZF-HD_dimer PF04770.12 GAN04825.1 - 6.1 7.3 5.9 8.4 6.8 0.2 3.1 3 0 0 3 3 3 0 ZF-HD protein dimerisation region zinc_ribbon_2 PF13240.6 GAN04825.1 - 9.6 6.1 7.6 18 5.2 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Sec1 PF00995.23 GAN04826.1 - 4.9e-110 369.4 0.0 3.9e-109 366.5 0.0 1.9 1 1 0 1 1 1 1 Sec1 family DUF1115 PF06544.12 GAN04827.1 - 1.7e-12 47.6 0.1 4.7e-12 46.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) ELMO_CED12 PF04727.13 GAN04828.1 - 3.1e-43 147.9 1.5 6.5e-43 146.9 1.5 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family UIM PF02809.20 GAN04829.1 - 0.0011 18.8 3.7 0.0011 18.8 3.7 3.3 3 0 0 3 3 3 1 Ubiquitin interaction motif UBZ_FAAP20 PF15750.5 GAN04829.1 - 0.39 10.7 2.0 0.89 9.6 0.8 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger TMEM43 PF07787.12 GAN04830.1 - 0.78 9.1 7.6 1.4 8.2 7.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 Acyltransferase PF01553.21 GAN04831.1 - 6.2e-10 38.8 0.0 1.9e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase TAF4 PF05236.14 GAN04832.1 - 2.1e-16 60.5 15.9 2.5e-16 60.2 0.0 3.8 2 2 1 4 4 4 2 Transcription initiation factor TFIID component TAF4 family Chordopox_A30L PF06015.12 GAN04832.1 - 0.11 12.3 0.5 0.32 10.8 0.5 1.8 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Usp PF00582.26 GAN04833.1 - 6.9e-28 97.9 0.0 1.2e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Oxidored_nitro PF00148.19 GAN04833.1 - 0.0073 15.1 0.1 0.0095 14.7 0.1 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Chitin_synth_1 PF01644.17 GAN04834.1 - 2.2e-78 261.8 0.0 3.6e-78 261.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAN04834.1 - 3.7e-30 103.7 0.1 1.3e-29 101.9 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAN04834.1 - 1.1e-19 70.5 2.6 1.8e-16 59.9 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN04834.1 - 0.00049 20.1 12.4 0.00049 20.1 12.4 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 CitMHS PF03600.16 GAN04834.1 - 0.0056 15.9 0.9 0.0094 15.2 0.9 1.3 1 0 0 1 1 1 1 Citrate transporter GYR PF02756.14 GAN04834.1 - 0.63 9.8 5.7 1.7 8.4 5.7 1.8 1 0 0 1 1 1 0 GYR motif RRM_1 PF00076.22 GAN04835.1 - 1.1e-13 50.8 0.0 3.7e-13 49.1 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APG6_N PF17675.1 GAN04835.1 - 0.026 15.1 1.0 0.026 15.1 1.0 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region Nup35_RRM_2 PF14605.6 GAN04835.1 - 0.089 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EF-hand_1 PF00036.32 GAN04836.1 - 1.4e-21 74.4 3.3 2.5e-06 26.6 0.1 5.6 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAN04836.1 - 5.7e-18 63.3 2.2 7.8e-05 22.3 0.0 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 GAN04836.1 - 2.7e-15 55.9 4.5 1.2e-10 41.1 0.0 4.5 3 3 2 5 5 5 3 EF-hand domain pair EF-hand_7 PF13499.6 GAN04836.1 - 2.1e-14 53.7 2.0 3.6e-06 27.3 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAN04836.1 - 2.2e-13 49.0 3.2 0.00029 20.2 0.0 4.1 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 GAN04836.1 - 0.032 14.5 0.7 0.4 11.0 0.8 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 GAN04836.1 - 0.093 12.6 1.0 5.2 7.0 0.0 2.9 2 1 0 3 3 3 0 Caleosin related protein EF-hand_6 PF13405.6 GAN04837.1 - 3.6e-05 23.3 1.0 0.00012 21.8 1.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 GAN04837.1 - 0.00078 18.8 1.7 0.00092 18.6 0.5 1.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GAN04837.1 - 0.0013 18.2 0.2 0.0031 17.0 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAN04837.1 - 0.0038 17.7 1.0 0.0038 17.7 1.0 2.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 GAN04837.1 - 0.023 14.5 0.3 0.11 12.4 0.1 2.0 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_like PF09279.11 GAN04837.1 - 0.058 13.9 0.2 0.16 12.5 0.1 1.8 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 GAN04838.1 - 1.2e-23 80.9 9.3 1.3e-06 27.5 0.1 5.8 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAN04838.1 - 1.7e-21 74.3 6.1 0.00047 19.9 0.1 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 GAN04838.1 - 1.9e-21 76.3 5.4 2.2e-10 40.8 0.0 3.2 2 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 GAN04838.1 - 1.1e-17 63.6 7.1 1.3e-10 40.9 0.0 4.7 3 3 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 GAN04838.1 - 8.9e-17 59.8 5.0 0.00015 21.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAN04838.1 - 0.0074 16.6 0.0 8.7 6.8 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 GAN04838.1 - 0.34 10.9 3.4 0.29 11.1 0.5 2.3 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN04838.1 - 0.73 10.2 2.7 5.2 7.4 1.2 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Oxysterol_BP PF01237.18 GAN04839.1 - 2e-117 392.2 5.8 2e-117 392.2 5.8 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 GAN04839.1 - 4.8e-21 74.8 0.2 1.2e-20 73.6 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAN04839.1 - 5.5e-11 42.9 1.1 6.2e-10 39.5 0.2 3.1 3 0 0 3 3 3 1 PH domain GOLD_2 PF13897.6 GAN04839.1 - 3.8e-06 27.5 3.1 0.00018 22.0 0.1 3.2 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking PH_11 PF15413.6 GAN04839.1 - 0.00035 21.0 6.7 0.38 11.2 0.0 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain EMP24_GP25L PF01105.24 GAN04839.1 - 0.023 14.6 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CE2_N PF17996.1 GAN04839.1 - 0.14 12.1 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal XPG_I_2 PF12813.7 GAN04840.1 - 6.1e-18 65.2 0.1 1.7e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 XPG domain containing XPG_N PF00752.17 GAN04840.1 - 9.7e-05 22.8 0.0 0.00057 20.3 0.0 2.2 1 1 0 1 1 1 1 XPG N-terminal domain DUF5615 PF18480.1 GAN04840.1 - 0.04 13.7 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) LON_substr_bdg PF02190.16 GAN04841.1 - 4.5e-17 62.6 0.0 7.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 GAN04841.1 - 2.3e-08 34.1 25.2 0.00018 21.6 9.7 2.4 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAN04841.1 - 2.7e-07 30.5 21.4 0.00074 19.5 7.9 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAN04841.1 - 7e-06 25.8 19.9 0.00059 19.6 9.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN04841.1 - 7.6e-06 25.7 20.2 0.00013 21.8 9.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN04841.1 - 1.3e-05 24.9 19.9 0.00026 20.8 7.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN04841.1 - 2.8e-05 24.0 23.0 0.00022 21.1 9.1 2.7 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN04841.1 - 0.00068 19.4 25.3 0.016 15.1 8.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 GAN04841.1 - 0.0015 18.3 13.5 0.012 15.5 1.3 2.6 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GAN04841.1 - 0.0088 16.2 18.2 0.1 12.8 4.1 2.4 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_2 PF13639.6 GAN04841.1 - 0.35 11.2 24.6 0.072 13.4 9.4 2.6 2 0 0 2 2 2 0 Ring finger domain zf-RRN7 PF11781.8 GAN04842.1 - 0.0072 16.0 0.7 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Gemini_mov PF01708.16 GAN04842.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF1460 PF07313.12 GAN04842.1 - 0.047 13.1 0.2 0.084 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) TRAUB PF08164.12 GAN04843.1 - 1.7e-28 98.9 0.4 1.7e-28 98.9 0.4 2.7 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 GAN04843.1 - 4.5e-26 92.2 0.8 4.5e-26 92.2 0.8 3.5 2 2 1 3 3 3 1 Apoptosis antagonizing transcription factor TACC_C PF05010.14 GAN04844.1 - 0.0047 16.7 1.3 0.0062 16.3 1.3 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CCDC-167 PF15188.6 GAN04844.1 - 0.042 14.2 1.2 0.07 13.5 1.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 KxDL PF10241.9 GAN04844.1 - 0.15 12.4 4.7 0.32 11.3 0.2 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein RasGEF PF00617.19 GAN04845.1 - 1.3e-57 194.8 1.1 1.3e-57 194.8 1.1 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAN04845.1 - 4e-27 94.5 0.3 4e-27 94.5 0.3 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 GAN04845.1 - 4.2e-14 51.9 0.1 8.2e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN04845.1 - 5.3e-11 42.0 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAN04845.1 - 1.3e-09 37.8 0.0 2.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 GAN04846.1 - 2.4e-48 164.9 18.3 2.4e-48 164.9 18.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN04846.1 - 2e-11 43.4 3.2 2e-11 43.4 3.2 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 GAN04846.1 - 0.00042 18.8 1.2 0.0012 17.2 1.2 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kinesin PF00225.23 GAN04848.1 - 1.6e-108 362.6 2.4 1.6e-108 362.6 2.4 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN04848.1 - 5.7e-25 88.0 0.1 5.7e-25 88.0 0.1 2.8 3 0 0 3 3 3 1 Microtubule binding Myb_DNA-bind_3 PF12776.7 GAN04848.1 - 0.13 13.3 6.3 0.75 10.8 1.0 3.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SNF5 PF04855.12 GAN04849.1 - 4.9e-68 229.5 4.6 4.9e-68 229.5 4.6 2.9 3 0 0 3 3 3 1 SNF5 / SMARCB1 / INI1 Cpn60_TCP1 PF00118.24 GAN04850.1 - 5.4e-146 487.1 12.4 6.2e-146 486.9 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3271 PF11675.8 GAN04850.1 - 0.0073 15.6 0.3 0.016 14.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3271) CRM1_repeat PF18777.1 GAN04850.1 - 0.075 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Dak2 PF02734.17 GAN04850.1 - 0.38 10.6 5.6 0.76 9.7 0.2 2.9 2 1 1 3 3 3 0 DAK2 domain Pkinase PF00069.25 GAN04851.1 - 2.9e-76 256.3 0.0 3.7e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04851.1 - 8.1e-39 133.5 0.0 1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN04851.1 - 9.1e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN04851.1 - 0.027 14.4 0.0 0.079 12.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2252 PF10009.9 GAN04851.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Haspin_kinase PF12330.8 GAN04851.1 - 0.066 12.1 0.1 0.12 11.3 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Sugar_tr PF00083.24 GAN04853.1 - 2.3e-95 320.1 35.6 3.3e-94 316.3 35.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN04853.1 - 7.1e-31 107.4 57.4 3.4e-25 88.7 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 GAN04854.1 - 1.6e-37 127.9 37.0 7.1e-12 45.8 1.0 4.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN04854.1 - 6.3e-21 72.2 13.1 0.00057 20.1 0.0 8.1 7 1 1 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 GAN04854.1 - 1.2e-20 73.3 15.4 5.1e-08 33.0 1.0 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN04854.1 - 7.3e-20 71.1 18.7 9e-09 35.7 0.8 6.0 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAN04854.1 - 2.9e-09 36.9 15.0 0.0056 17.1 0.7 6.4 7 0 0 7 7 7 3 Ankyrin repeat Adaptin_binding PF10199.9 GAN04855.1 - 4e-09 37.1 2.4 4e-09 37.1 2.4 1.7 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 FSA_C PF10479.9 GAN04855.1 - 5.1 5.1 7.1 7.6 4.5 7.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SCAI PF12070.8 GAN04857.1 - 3.4e-176 587.2 3.8 1.6e-174 581.7 3.8 2.2 1 1 0 1 1 1 1 Protein SCAI TFIIA PF03153.13 GAN04858.1 - 4.7 7.1 38.7 0.71 9.8 34.5 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AMP-binding PF00501.28 GAN04859.1 - 3.4e-18 65.5 0.0 3.9e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme RNA_POL_M_15KD PF02150.16 GAN04859.1 - 0.15 12.0 0.3 0.32 10.9 0.1 1.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit NAD_binding_4 PF07993.12 GAN04860.1 - 4.7e-35 121.0 0.0 1.7e-32 112.6 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein PP-binding PF00550.25 GAN04860.1 - 2e-07 31.3 0.0 6.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding PF00501.28 GAN04860.1 - 5.8e-06 25.2 0.1 2.4e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAN04860.1 - 5.3e-05 22.8 0.0 0.00063 19.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 GAN04860.1 - 0.047 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Polysacc_synt_2 PF02719.15 GAN04860.1 - 0.098 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YtxH PF12732.7 GAN04860.1 - 0.11 13.0 1.1 1.1 9.9 0.2 2.6 2 0 0 2 2 2 0 YtxH-like protein Menin PF05053.13 GAN04861.1 - 1.2 7.4 8.5 1.7 6.9 8.5 1.3 1 0 0 1 1 1 0 Menin PI3K_1B_p101 PF10486.9 GAN04861.1 - 2.1 6.0 15.4 2.9 5.6 15.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1752 PF08550.10 GAN04862.1 - 3.9e-12 45.8 4.0 7.6e-12 44.9 4.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Spem1 PF15670.5 GAN04862.1 - 0.28 10.7 4.6 0.17 11.4 0.6 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 FH2 PF02181.23 GAN04863.1 - 8.9e-73 245.5 9.0 8.9e-73 245.5 9.0 2.5 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAN04863.1 - 7.2e-32 110.5 0.1 7.2e-32 110.5 0.1 2.6 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAN04863.1 - 8e-25 87.6 0.2 8e-25 87.6 0.2 3.9 3 2 0 3 3 3 1 Diaphanous FH3 Domain FANCI_HD2 PF14680.6 GAN04864.1 - 0.06 12.6 0.1 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 FANCI helical domain 2 zf-Tim10_DDP PF02953.15 GAN04865.1 - 1.5e-19 69.4 1.9 1.5e-19 69.4 1.9 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 GAN04865.1 - 0.0033 17.7 0.1 0.063 13.5 0.0 2.0 1 1 1 2 2 2 1 Phasin protein DUF842 PF05811.13 GAN04865.1 - 0.02 14.6 2.3 0.056 13.1 2.2 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Phos_pyr_kin PF08543.12 GAN04866.1 - 1.1e-16 61.0 0.1 2.1e-16 60.1 0.1 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 GAN04866.1 - 2e-09 37.2 0.0 2.2e-08 33.8 0.0 2.3 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Glutaredoxin PF00462.24 GAN04867.1 - 3.9e-14 52.6 0.0 6.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Bac_A_amyl_C PF18612.1 GAN04867.1 - 0.005 16.6 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial Alpha amylase C-terminal domain GST_N_3 PF13417.6 GAN04867.1 - 0.0054 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 GAN04867.1 - 0.018 15.4 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraP PF07296.11 GAN04867.1 - 0.059 12.6 0.1 0.07 12.3 0.1 1.1 1 0 0 1 1 1 0 TraP protein GST_N_2 PF13409.6 GAN04867.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Arrestin_C PF02752.22 GAN04868.1 - 2.2e-13 50.8 0.5 9.9e-07 29.3 0.1 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN04868.1 - 2.3e-09 37.4 0.0 4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 GAN04868.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Rgp1 WD-3 PF09765.9 GAN04869.1 - 1.5e-53 182.0 3.0 2e-53 181.6 3.0 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 GAN04869.1 - 6.7e-11 42.2 2.5 1.3e-10 41.3 2.5 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 GAN04869.1 - 0.017 15.4 0.4 0.037 14.3 0.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 GAN04869.1 - 0.089 13.1 4.9 0.057 13.8 2.8 1.8 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 GAN04869.1 - 0.14 12.1 1.9 0.28 11.1 1.9 1.5 1 0 0 1 1 1 0 PHD-finger Myb_DNA-binding PF00249.31 GAN04870.1 - 5.5e-05 23.3 0.5 0.00024 21.2 0.0 2.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN04870.1 - 0.015 15.5 0.3 0.1 12.9 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Allexi_40kDa PF05549.11 GAN04870.1 - 0.061 12.8 0.8 0.095 12.2 0.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DivIC PF04977.15 GAN04870.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Ras PF00071.22 GAN04871.1 - 1.6e-48 164.4 0.0 1.9e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN04871.1 - 8.5e-20 71.2 0.0 1.3e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN04871.1 - 3.8e-05 23.2 0.0 6.1e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN04871.1 - 0.0058 16.0 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN04871.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase HSP9_HSP12 PF04119.12 GAN04872.1 - 0.023 15.1 2.1 0.036 14.4 0.1 2.0 1 1 1 2 2 2 0 Heat shock protein 9/12 Chi-conotoxin PF16981.5 GAN04872.1 - 0.82 10.0 3.0 13 6.1 3.0 2.1 1 1 0 1 1 1 0 chi-Conotoxin or t superfamily Vma12 PF11712.8 GAN04873.1 - 6.8e-23 81.3 0.1 1e-22 80.7 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Hpr_kinase_N PF02603.16 GAN04873.1 - 0.015 15.3 0.0 0.64 10.1 0.0 2.2 1 1 1 2 2 2 0 HPr Serine kinase N terminus Band_7_1 PF13421.6 GAN04874.1 - 0.15 11.8 0.2 0.94 9.1 0.0 2.1 2 0 0 2 2 2 0 SPFH domain-Band 7 family Macoilin PF09726.9 GAN04875.1 - 1.7 7.1 6.4 2.3 6.7 6.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4588 PF15251.6 GAN04876.1 - 6e-05 22.9 2.6 6e-05 22.9 2.6 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) DegT_DnrJ_EryC1 PF01041.17 GAN04876.1 - 0.038 13.3 0.2 0.038 13.3 0.2 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Arginase PF00491.21 GAN04877.1 - 2e-86 290.0 0.0 2.4e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 GAN04877.1 - 0.0024 18.1 0.1 0.0043 17.3 0.1 1.4 1 0 0 1 1 1 1 UPF0489 domain Tox-REase-9 PF15650.6 GAN04877.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 Sel1 PF08238.12 GAN04878.1 - 1.4e-33 114.5 30.2 4.8e-09 36.6 0.0 11.5 11 0 0 11 11 11 8 Sel1 repeat TPR_6 PF13174.6 GAN04878.1 - 3.3e-05 24.2 2.8 23 5.9 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN04878.1 - 0.0072 16.3 0.2 6 7.1 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat U79_P34 PF03064.16 GAN04878.1 - 0.51 9.6 5.2 0.94 8.8 5.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_1 PF00515.28 GAN04878.1 - 0.59 10.1 10.3 7.2 6.6 0.9 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_ab_N PF02874.23 GAN04879.1 - 8.1e-24 83.9 1.7 8.1e-24 83.9 1.7 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 GAN04879.1 - 4.9e-10 39.4 0.6 9.3e-10 38.5 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 GAN04879.1 - 0.0054 15.9 0.1 0.0078 15.4 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 GAN04879.1 - 0.035 14.0 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GAN04879.1 - 0.04 14.3 0.1 0.09 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 GAN04879.1 - 0.056 13.8 0.1 0.099 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain CSD2 PF17876.1 GAN04879.1 - 0.074 13.2 0.9 0.4 10.9 0.4 2.2 2 0 0 2 2 2 0 Cold shock domain RNA_helicase PF00910.22 GAN04879.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 GAN04879.1 - 0.12 11.2 0.1 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 GAN04879.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 GAN04879.1 - 0.13 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 GAN04879.1 - 0.21 11.8 0.1 0.39 11.0 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAN04879.1 - 0.22 12.0 0.9 0.49 10.9 0.4 1.7 2 0 0 2 2 2 0 ABC transporter Lipase_GDSL PF00657.22 GAN04880.1 - 2.6e-14 53.7 0.0 3.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN04880.1 - 7.1e-07 29.8 0.1 5.7e-06 26.9 0.1 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 GAN04880.1 - 0.12 12.5 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF1279 PF06916.13 GAN04881.1 - 4.1e-06 27.3 0.0 6.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Rib_5-P_isom_A PF06026.14 GAN04882.1 - 5.7e-59 198.6 0.0 7e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GAN04882.1 - 0.011 15.7 0.0 4.7 7.1 0.0 2.2 1 1 1 2 2 2 0 DeoR C terminal sensor domain Sugar-bind PF04198.13 GAN04882.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain WD40 PF00400.32 GAN04883.1 - 2.1e-37 126.4 29.4 1.7e-06 28.7 0.5 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 GAN04883.1 - 5.1e-09 35.3 12.8 0.048 12.3 0.0 5.6 5 1 1 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN04883.1 - 3.2e-07 30.5 1.7 0.14 12.5 0.0 4.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAN04883.1 - 4.9e-07 29.5 1.0 1e-06 28.5 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN04883.1 - 1.3e-06 28.1 0.7 2.7e-06 27.1 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAN04883.1 - 0.0025 17.7 0.2 0.0063 16.4 0.2 1.7 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 GAN04883.1 - 0.0039 16.6 0.0 0.051 12.9 0.0 2.3 1 1 0 1 1 1 1 WD40-like domain Peptidase_S29 PF02907.15 GAN04883.1 - 0.0098 15.6 0.3 0.038 13.7 0.1 2.0 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease HSP70 PF00012.20 GAN04884.1 - 3e-166 554.1 5.1 3e-166 554.1 5.1 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GAN04884.1 - 6e-12 45.0 0.5 3.7e-11 42.4 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 GAN04884.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain POTRA PF07244.15 GAN04884.1 - 0.11 13.1 0.8 3.7 8.2 0.1 3.1 1 1 0 2 2 2 0 Surface antigen variable number repeat Asn_synthase PF00733.21 GAN04885.1 - 3e-94 316.6 0.3 3.8e-58 197.8 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GAN04885.1 - 8.6e-42 141.9 0.0 1.6e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAN04885.1 - 1.1e-33 116.2 0.0 2.6e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAN04885.1 - 1.9e-08 34.0 0.0 3.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAN04885.1 - 0.024 13.7 0.0 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 NAD synthase Hairy_orange PF07527.13 GAN04885.1 - 0.047 13.9 0.1 9.6 6.5 0.0 3.1 3 0 0 3 3 3 0 Hairy Orange QueC PF06508.13 GAN04885.1 - 0.13 11.7 0.1 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC GATA PF00320.27 GAN04886.1 - 4.7e-15 54.9 4.2 4.7e-15 54.9 4.2 2.4 2 0 0 2 2 2 1 GATA zinc finger zf-RRN7 PF11781.8 GAN04886.1 - 0.00091 18.9 8.1 0.0048 16.6 0.2 3.1 2 1 1 3 3 3 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 GAN04886.1 - 0.024 14.7 3.2 1.9 8.7 0.1 3.1 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 GAN04886.1 - 0.028 14.3 1.7 0.12 12.2 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Kinesin_assoc PF16183.5 GAN04886.1 - 0.041 14.0 0.4 0.089 12.9 0.4 1.5 1 0 0 1 1 1 0 Kinesin-associated TF_Zn_Ribbon PF08271.12 GAN04886.1 - 0.041 13.4 0.3 0.041 13.4 0.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding HALZ PF02183.18 GAN04886.1 - 0.043 14.0 0.9 0.11 12.8 0.9 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Apocytochr_F_N PF16639.5 GAN04886.1 - 0.24 11.7 2.7 0.45 10.8 0.3 2.5 2 1 1 3 3 3 0 Apocytochrome F, N-terminal FAM163 PF15069.6 GAN04886.1 - 1.4 9.4 13.5 2.9 8.3 1.3 2.9 2 1 0 3 3 3 0 FAM163 family Ribosomal_S30AE PF02482.19 GAN04887.1 - 0.015 16.1 1.8 0.6 10.9 0.0 3.3 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Acyl-CoA_dh_2 PF08028.11 GAN04887.1 - 1.4 9.2 6.1 0.2 11.9 0.6 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Lactamase_B_6 PF16661.5 GAN04888.1 - 1e-09 38.1 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 GAN04888.1 - 0.0014 18.8 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 GAN04888.1 - 0.02 14.1 0.0 0.054 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative beta-lactamase-like family DUF641 PF04859.12 GAN04888.1 - 0.038 14.3 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) COE1_HLH PF16423.5 GAN04888.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain Thg1 PF04446.12 GAN04889.1 - 7e-52 174.7 0.2 9.9e-52 174.2 0.2 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 GAN04889.1 - 5.5e-41 139.6 0.1 8.5e-41 138.9 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain SUZ PF12752.7 GAN04890.1 - 0.00094 19.9 0.9 0.00094 19.9 0.9 1.9 2 1 0 2 2 2 1 SUZ domain PTN_MK_C PF01091.18 GAN04890.1 - 0.014 15.7 0.8 0.014 15.7 0.8 1.6 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain SdpI PF13630.6 GAN04890.1 - 0.18 12.0 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family MBOAT PF03062.19 GAN04891.1 - 2.6e-40 138.8 18.8 6.2e-40 137.6 18.8 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DPM3 PF08285.11 GAN04891.1 - 8.8e-31 106.0 0.3 4.3e-30 103.8 0.0 2.4 2 0 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Ribosomal_S17e PF00833.18 GAN04892.1 - 5.4e-63 210.4 0.2 8.3e-63 209.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal S17 C2 PF00168.30 GAN04893.1 - 2.4e-58 194.8 9.2 1.9e-17 63.4 0.1 6.5 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 GAN04893.1 - 8.7e-07 28.6 0.0 1.2e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FAM104 PF15434.6 GAN04893.1 - 3.1 8.4 7.3 6.2 7.4 0.1 2.7 2 0 0 2 2 2 0 Family 104 DUF1729 PF08354.10 GAN04894.1 - 1.5e-150 501.0 0.0 2.8e-150 500.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 GAN04894.1 - 1.2e-71 241.8 0.0 4.6e-71 239.9 0.0 2.1 3 0 0 3 3 3 1 Acyl transferase domain FAS_I_H PF18314.1 GAN04894.1 - 2e-69 233.3 0.0 3.9e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 GAN04894.1 - 5.3e-68 228.4 0.0 1.3e-67 227.1 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 GAN04894.1 - 1.5e-46 157.8 0.0 3.9e-46 156.5 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 GAN04894.1 - 5.3e-30 103.5 0.1 1.4e-29 102.2 0.1 1.7 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 GAN04894.1 - 2.2e-29 102.9 0.0 4.8e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 GAN04894.1 - 3.3e-28 98.3 0.3 7.9e-28 97.0 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta ketoacyl-synt PF00109.26 GAN04894.1 - 9.3e-22 77.8 0.3 2.7e-21 76.3 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MaoC_dehydrat_N PF13452.6 GAN04894.1 - 1.8e-17 63.7 0.0 5.7e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase ACPS PF01648.20 GAN04894.1 - 3.4e-15 56.2 0.0 8.6e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 GAN04894.1 - 1.1e-09 38.3 0.0 3.2e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAN04894.1 - 0.031 13.6 0.2 0.088 12.2 0.2 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain Sulfotransfer_3 PF13469.6 GAN04896.1 - 2.7e-08 34.5 0.1 0.0028 18.1 0.2 3.1 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 GAN04896.1 - 9.6e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain CTP_transf_like PF01467.26 GAN04897.1 - 9.3e-09 35.6 0.0 2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2201 PF09967.9 GAN04897.1 - 0.059 13.5 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 VWA-like domain (DUF2201) DPBB_1 PF03330.18 GAN04897.1 - 0.063 13.6 0.1 0.19 12.0 0.0 1.7 1 1 1 2 2 2 0 Lytic transglycolase UQ_con PF00179.26 GAN04898.1 - 1.1e-44 151.5 0.0 1.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 GAN04898.1 - 0.0017 18.0 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 GAN04898.1 - 0.018 15.3 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 GAN04898.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 GAN04898.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain PA_decarbox PF05870.11 GAN04899.1 - 0.034 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) DUF1072 PF06380.11 GAN04899.1 - 7 6.6 6.8 28 4.7 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Cu-oxidase_2 PF07731.14 GAN04900.1 - 6.2e-40 136.1 10.0 1.5e-38 131.6 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAN04900.1 - 1.2e-36 125.3 9.0 1.1e-34 119.0 0.8 4.4 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 GAN04900.1 - 2e-32 112.5 4.6 3.8e-32 111.6 0.8 2.8 3 0 0 3 3 3 1 Multicopper oxidase DUF4249 PF14054.6 GAN04900.1 - 0.031 13.9 0.3 0.05 13.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) zf-C2H2_jaz PF12171.8 GAN04901.1 - 0.0015 18.7 1.0 0.003 17.8 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAN04901.1 - 0.024 14.9 0.5 0.024 14.9 0.5 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAN04901.1 - 0.025 14.9 0.3 0.044 14.2 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type GDP_Man_Dehyd PF16363.5 GAN04902.1 - 2e-163 543.5 0.0 2.3e-163 543.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAN04902.1 - 8.6e-76 254.6 0.0 1.1e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAN04902.1 - 7.4e-08 31.8 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAN04902.1 - 2.7e-05 23.4 0.0 4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GAN04902.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAN04902.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Zn_clus PF00172.18 GAN04903.1 - 0.0043 17.1 19.0 0.0088 16.1 11.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAN04903.1 - 0.18 11.8 0.0 0.52 10.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold zf-C2H2_2 PF12756.7 GAN04904.1 - 0.055 13.8 6.3 1.1 9.7 6.4 2.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN04904.1 - 0.14 13.1 12.6 0.35 11.8 4.6 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN04904.1 - 4.8 7.8 13.5 6.7 7.4 0.7 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type GAGA PF09237.11 GAN04904.1 - 5.4 6.9 6.3 0.29 11.0 0.5 1.8 2 0 0 2 2 2 0 GAGA factor Mso1_Sec1_bdg PF14475.6 GAN04905.1 - 2.8e-06 26.8 0.3 8.7e-06 25.2 0.3 1.9 1 0 0 1 1 1 1 Sec1-binding region of Mso1 DUF2181 PF10223.9 GAN04905.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) DNA_methylase PF00145.17 GAN04905.1 - 0.031 13.6 3.7 0.045 13.1 3.7 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase HNH_5 PF14279.6 GAN04905.1 - 0.37 10.7 4.0 0.28 11.1 0.3 2.5 3 0 0 3 3 3 0 HNH endonuclease DUF737 PF05300.11 GAN04905.1 - 8.5 6.7 12.8 55 4.0 12.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Acyl-CoA_dh_1 PF00441.24 GAN04906.1 - 7.1e-32 110.7 0.3 1.1e-31 110.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 GAN04906.1 - 2.8e-19 69.0 0.0 6.6e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 GAN04906.1 - 5.4e-19 68.2 0.2 9.7e-19 67.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAN04906.1 - 2e-10 41.3 0.0 4.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAN04906.1 - 2.5e-08 34.3 0.0 5.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyltransferase PF01553.21 GAN04907.1 - 5.3e-14 52.0 0.0 9.2e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NIF PF03031.18 GAN04908.1 - 2.5e-24 85.8 0.1 4.3e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 GAN04908.1 - 8.6e-09 35.2 0.1 2.1e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 GAN04908.1 - 7.5e-07 29.4 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAN04908.1 - 0.0012 19.1 0.2 0.0047 17.2 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Raftlin PF15250.6 GAN04908.1 - 9.8 4.8 12.8 26 3.4 12.8 1.7 1 0 0 1 1 1 0 Raftlin Pkinase PF00069.25 GAN04909.1 - 2.7e-51 174.4 0.2 2.7e-51 174.4 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04909.1 - 1.1e-24 87.1 0.0 4.2e-23 82.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 GAN04909.1 - 2.8e-20 72.3 6.5 1.2e-09 38.2 0.1 3.7 3 0 0 3 3 3 2 POLO box duplicated region Pkinase_fungal PF17667.1 GAN04909.1 - 0.0024 16.7 0.4 0.0024 16.7 0.4 2.4 3 0 0 3 3 3 1 Fungal protein kinase AA_permease PF00324.21 GAN04910.1 - 7.2e-130 433.8 56.8 8.5e-130 433.5 56.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN04910.1 - 7.3e-40 137.1 61.2 1.2e-39 136.3 61.2 1.3 1 1 0 1 1 1 1 Amino acid permease Ank_2 PF12796.7 GAN04911.1 - 2e-45 153.2 15.5 4.8e-14 52.7 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN04911.1 - 4e-34 116.6 7.3 9.9e-07 29.2 0.0 7.0 4 4 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN04911.1 - 1.9e-29 98.4 6.6 5e-06 26.4 0.0 8.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 GAN04911.1 - 1.4e-27 95.3 5.3 9.4e-08 32.2 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAN04911.1 - 2e-21 75.4 12.1 0.00083 19.7 0.0 8.0 7 1 0 7 7 7 4 Ankyrin repeat Shigella_OspC PF06128.11 GAN04911.1 - 0.009 15.8 0.0 2.1 8.0 0.0 3.0 3 0 0 3 3 3 1 Shigella flexneri OspC protein AnkUBD PF18418.1 GAN04911.1 - 0.059 13.5 0.1 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain Abhydrolase_3 PF07859.13 GAN04912.1 - 4.2e-51 173.8 0.0 6.1e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN04912.1 - 4.7e-16 58.6 0.0 2.1e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 GAN04912.1 - 0.016 14.5 0.0 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 GAN04912.1 - 0.031 13.2 0.0 0.12 11.2 0.0 1.9 1 1 0 1 1 1 0 Carboxylesterase family Peptidase_S9 PF00326.21 GAN04912.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Dfp1_Him1_M PF08630.10 GAN04913.1 - 4.1e-25 88.4 0.0 4.1e-25 88.4 0.0 3.0 2 1 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 GAN04913.1 - 8.8e-15 54.6 2.2 1.9e-14 53.5 2.2 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 GAN04913.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 GAN04913.1 - 0.0029 18.0 0.0 0.0076 16.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Oxysterol_BP PF01237.18 GAN04913.1 - 0.31 9.8 10.0 0.56 9.0 10.0 1.4 1 0 0 1 1 1 0 Oxysterol-binding protein NIF PF03031.18 GAN04914.1 - 2.9e-24 85.6 2.1 3e-24 85.6 0.4 1.9 2 1 1 3 3 3 1 NLI interacting factor-like phosphatase Ribonuclease_P PF00825.18 GAN04915.1 - 9.8e-11 41.7 0.1 1.2e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease P Pre-PUA PF17832.1 GAN04915.1 - 0.067 13.9 0.0 0.13 13.0 0.0 1.5 2 0 0 2 2 2 0 Pre-PUA-like domain FHA PF00498.26 GAN04916.1 - 5.2e-15 55.6 2.3 6.2e-15 55.3 0.5 2.1 2 0 0 2 2 2 1 FHA domain PH PF00169.29 GAN04916.1 - 1.5e-11 44.7 0.0 3.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Yop-YscD_cpl PF16697.5 GAN04916.1 - 1.5e-07 31.6 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PX PF00787.24 GAN04916.1 - 4.4e-06 26.7 0.1 1.1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 PX domain Laminin_G_3 PF13385.6 GAN04916.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DDE_3 PF13358.6 GAN04917.1 - 9.9e-10 38.3 0.1 1.4e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease GATA PF00320.27 GAN04919.1 - 2e-18 65.7 13.3 6.1e-16 57.7 4.6 2.4 2 0 0 2 2 2 2 GATA zinc finger Elf1 PF05129.13 GAN04919.1 - 1.4 9.1 8.8 1.7 8.7 2.9 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Cytochrom_c3_2 PF14537.6 GAN04919.1 - 3 8.4 17.8 0.85 10.1 2.8 2.9 2 1 1 3 3 3 0 Cytochrome c3 Sporozoite_P67 PF05642.11 GAN04919.1 - 8.1 4.4 10.3 0.21 9.7 3.2 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ribosomal_S27e PF01667.17 GAN04920.1 - 6.8e-29 99.4 3.6 1.1e-28 98.7 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Acyltransferase PF01553.21 GAN04920.1 - 2.5e-16 59.5 0.0 6.8e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase TF_Zn_Ribbon PF08271.12 GAN04920.1 - 0.016 14.7 3.1 0.016 14.7 3.1 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 GAN04920.1 - 0.14 12.2 1.2 0.27 11.3 1.2 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FA_desaturase PF00487.24 GAN04920.1 - 0.28 11.0 4.8 0.47 10.2 4.8 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Prok-RING_1 PF14446.6 GAN04920.1 - 0.4 10.6 2.2 0.8 9.7 2.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.21 GAN04920.1 - 0.97 9.7 2.7 1.1 9.5 0.9 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Dynamin_M PF01031.20 GAN04922.1 - 3.7e-104 347.9 1.0 2.6e-103 345.2 0.1 2.2 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 GAN04922.1 - 1.1e-56 191.5 0.6 3.2e-56 190.0 0.1 2.0 2 0 0 2 2 2 1 Dynamin family Ribosomal_S21e PF01249.18 GAN04922.1 - 1.3e-36 124.6 0.1 2.4e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S21e GED PF02212.18 GAN04922.1 - 1.7e-26 92.2 4.6 1.7e-26 92.2 4.6 2.1 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAN04922.1 - 5.8e-05 23.1 0.2 0.00021 21.3 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSC PF11356.8 GAN04922.1 - 0.22 11.4 2.9 0.44 10.4 2.9 1.3 1 0 0 1 1 1 0 Type II secretion system protein C DRMBL PF07522.14 GAN04923.1 - 1.1e-34 118.9 2.0 1.6e-33 115.2 0.4 2.5 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAN04923.1 - 2e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAN04923.1 - 0.005 16.9 3.3 0.016 15.2 3.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HLH PF00010.26 GAN04924.1 - 3.3e-16 59.0 0.0 1.8e-15 56.6 0.0 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Herpes_UL6 PF01763.16 GAN04924.1 - 0.041 12.4 0.6 1.9 6.9 0.0 2.3 2 1 0 2 2 2 0 Herpesvirus UL6 like PKcGMP_CC PF16808.5 GAN04924.1 - 0.48 10.3 6.4 0.28 11.1 1.0 2.9 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MerR-DNA-bind PF09278.11 GAN04924.1 - 1.5 9.4 5.0 12 6.6 1.4 2.3 2 0 0 2 2 2 0 MerR, DNA binding PPR_2 PF13041.6 GAN04925.1 - 2.9e-58 193.9 24.1 9.7e-09 35.3 1.1 15.0 9 5 8 17 17 17 12 PPR repeat family PPR_3 PF13812.6 GAN04925.1 - 2.4e-36 123.6 12.5 6.6e-07 29.3 0.0 11.7 10 3 3 13 13 13 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAN04925.1 - 2.7e-32 110.2 13.3 4e-06 26.4 0.0 13.4 15 0 0 15 15 15 7 PPR repeat PPR PF01535.20 GAN04925.1 - 2.5e-27 93.1 26.8 0.0044 17.2 0.0 17.0 19 0 0 19 19 19 8 PPR repeat PPR_long PF17177.4 GAN04925.1 - 2.7e-22 79.2 4.4 2.2e-09 37.0 0.0 5.9 4 2 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAN04925.1 - 3.9e-06 27.2 0.0 3.5 8.7 0.0 7.5 9 1 1 10 10 10 1 Tetratricopeptide repeat RPM2 PF08579.11 GAN04925.1 - 7.6e-05 23.1 2.9 0.48 10.8 0.1 5.7 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) SPOB_a PF14689.6 GAN04925.1 - 0.0011 18.7 0.1 0.05 13.3 0.0 3.6 4 0 0 4 4 4 1 Sensor_kinase_SpoOB-type, alpha-helical domain ANAPC3 PF12895.7 GAN04925.1 - 0.18 12.0 2.3 5.3 7.3 0.0 4.1 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TMEM164 PF14808.6 GAN04926.1 - 1e-12 47.9 13.6 4.3e-11 42.7 13.6 2.2 1 1 0 1 1 1 1 TMEM164 family RRM_1 PF00076.22 GAN04927.1 - 2.7e-14 52.7 0.0 2.2e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 GAN04928.1 - 2.5e-50 170.2 2.6 2.9e-50 170.0 2.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAN04928.1 - 2.4e-05 24.7 0.0 3.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAN04928.1 - 2.9e-05 24.1 0.4 4.9e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 GAN04928.1 - 0.0054 17.3 0.4 0.0068 17.0 0.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 GAN04928.1 - 0.0062 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAN04928.1 - 0.045 13.8 0.2 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN04928.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 GAN04929.1 - 2.6e-08 33.9 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 GAN04929.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 GAN04929.1 - 9.7e-05 22.7 0.1 0.00013 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 GAN04929.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAN04929.1 - 0.00035 20.8 0.1 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAN04929.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN04929.1 - 0.059 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 GAN04929.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Ribosomal_60s PF00428.19 GAN04930.1 - 5e-20 71.9 2.6 7.7e-20 71.3 2.6 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein CwfJ_C_1 PF04677.15 GAN04932.1 - 3.2e-29 101.3 0.0 9.1e-29 99.8 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 GAN04932.1 - 8.8e-22 76.6 26.9 2.6e-10 39.9 4.7 7.5 8 0 0 8 8 8 3 Zinc knuckle CwfJ_C_2 PF04676.14 GAN04932.1 - 1.3e-14 54.8 0.0 3.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 GAN04932.1 - 1.6e-12 46.9 19.4 0.00028 20.8 0.9 4.6 3 0 0 3 3 3 3 Zinc knuckle zf-C2H2 PF00096.26 GAN04932.1 - 0.00037 20.8 8.3 0.00073 19.9 1.9 11.2 11 0 0 11 11 11 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN04932.1 - 0.00053 20.6 93.8 0.0068 17.2 2.2 10.7 11 0 0 11 11 11 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN04932.1 - 0.0014 18.8 66.6 0.0032 17.7 1.2 8.5 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN04932.1 - 0.0064 16.8 1.5 0.0064 16.8 1.5 8.9 9 0 0 9 9 9 3 Zinc-finger of C2H2 type HIT PF01230.23 GAN04932.1 - 0.0092 16.7 0.0 0.032 15.0 0.0 1.9 1 0 0 1 1 1 1 HIT domain MF_alpha PF04648.12 GAN04932.1 - 0.079 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Yeast mating factor alpha hormone RNA_pol_Rpb5_N PF03871.14 GAN04932.1 - 0.1 13.2 0.0 0.32 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain zf-CCHC_4 PF14392.6 GAN04932.1 - 1.2 8.9 10.8 15 5.4 0.3 3.9 3 0 0 3 3 3 0 Zinc knuckle zf-C2H2_3rep PF18868.1 GAN04932.1 - 3.2 8.4 19.2 0.26 12.0 0.2 5.8 5 1 1 6 6 6 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 GAN04932.1 - 9.6 6.9 13.7 26 5.5 0.1 5.9 6 0 0 6 6 6 0 FOXP coiled-coil domain GST_N_3 PF13417.6 GAN04933.1 - 7.4e-16 58.3 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAN04933.1 - 5.1e-13 49.2 0.0 1.1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN04933.1 - 6.6e-13 48.8 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 GAN04933.1 - 8.3e-11 42.4 0.2 3e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN04933.1 - 2e-08 34.2 0.2 9.2e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAN04933.1 - 2.5e-05 24.4 0.2 5.4e-05 23.3 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN04933.1 - 0.0012 19.0 0.0 0.0034 17.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 14-3-3 PF00244.20 GAN04933.1 - 0.051 13.1 0.6 0.075 12.5 0.6 1.2 1 0 0 1 1 1 0 14-3-3 protein Glutaredoxin PF00462.24 GAN04933.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin Peptidase_M24 PF00557.24 GAN04934.1 - 2.4e-47 161.3 0.0 3.7e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 CytochromB561_N PF09786.9 GAN04934.1 - 8e-05 21.8 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF4949 PF16307.5 GAN04934.1 - 0.026 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) DUF2618 PF10940.8 GAN04934.1 - 0.053 13.3 2.9 0.13 12.1 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) VKOR PF07884.14 GAN04934.1 - 0.086 13.0 1.8 0.17 12.1 1.8 1.4 1 0 0 1 1 1 0 Vitamin K epoxide reductase family E1_DerP2_DerF2 PF02221.15 GAN04935.1 - 6.7e-23 81.6 0.3 8.1e-23 81.3 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAN04935.1 - 7.5e-05 23.1 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 ML-like domain Alph_Pro_TM PF09608.10 GAN04935.1 - 0.049 13.4 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF1091 PF06477.13 GAN04935.1 - 0.05 14.1 0.1 0.1 13.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) Fe_bilin_red PF05996.12 GAN04936.1 - 0.095 12.4 2.6 0.19 11.4 1.5 1.7 1 1 1 2 2 2 0 Ferredoxin-dependent bilin reductase Cgr1 PF03879.14 GAN04936.1 - 0.86 10.0 13.6 4 7.9 13.6 1.9 1 1 0 1 1 1 0 Cgr1 family Colicin_im PF03857.13 GAN04937.1 - 0.0078 16.2 0.5 0.0089 16.0 0.5 1.1 1 0 0 1 1 1 1 Colicin immunity protein Actin PF00022.19 GAN04938.1 - 3.6e-152 506.7 0.0 1.4e-151 504.8 0.0 1.7 1 1 0 1 1 1 1 Actin zf-C2H2 PF00096.26 GAN04940.1 - 0.00065 20.0 20.6 0.011 16.2 0.4 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN04940.1 - 0.0026 18.5 21.9 0.098 13.6 0.4 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 GAN04940.1 - 0.02 14.7 0.1 0.02 14.7 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 GAN04940.1 - 0.08 13.3 10.9 1.7 9.0 0.1 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 GAN04940.1 - 0.15 12.2 1.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-Di19 PF05605.12 GAN04940.1 - 0.29 11.5 15.6 1 9.7 3.0 3.7 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 GAN04940.1 - 0.7 10.6 4.6 16 6.3 0.1 3.8 2 2 2 4 4 4 0 FOXP coiled-coil domain ResIII PF04851.15 GAN04941.1 - 5.8e-22 78.5 0.0 2.5e-21 76.4 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN04941.1 - 5.4e-19 68.6 0.1 1.3e-18 67.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN04941.1 - 5.2e-15 55.7 0.0 1.3e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAN04941.1 - 0.0019 17.4 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase EHN PF06441.12 GAN04943.1 - 4.3e-26 91.4 2.8 9.8e-26 90.2 2.8 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAN04943.1 - 6.6e-17 62.0 0.2 1.2e-16 61.1 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN04943.1 - 1.1e-06 29.4 0.1 2.8e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family US2 PF02476.15 GAN04944.1 - 0.022 15.5 1.0 2.3 8.9 0.0 2.4 2 0 0 2 2 2 0 US2 family DUF5568 PF17724.1 GAN04944.1 - 0.042 13.7 10.1 0.074 12.9 1.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5568) DUF3246 PF11596.8 GAN04944.1 - 0.11 11.9 8.1 0.16 11.3 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Tim54 PF11711.8 GAN04944.1 - 1.7 7.3 15.2 1.8 7.3 5.3 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Med19 PF10278.9 GAN04944.1 - 3.6 7.5 30.6 2.6 7.9 9.6 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Tyr-DNA_phospho PF06087.12 GAN04945.1 - 3.7e-89 299.5 1.3 5.2e-57 193.6 0.8 2.0 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase TCL1_MTCP1 PF01840.17 GAN04945.1 - 0.025 14.2 0.6 0.056 13.1 0.1 1.7 2 0 0 2 2 2 0 TCL1/MTCP1 family Esterase PF00756.20 GAN04946.1 - 1.3e-60 205.1 0.0 1.5e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GAN04946.1 - 9.9e-07 28.4 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAN04946.1 - 0.00025 20.0 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GAN04946.1 - 0.0003 20.2 0.0 0.00067 19.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 GAN04946.1 - 0.003 17.1 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase PAF-AH_p_II PF03403.13 GAN04946.1 - 0.0035 15.9 0.0 0.0052 15.3 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S15 PF02129.18 GAN04946.1 - 0.011 15.4 0.0 0.039 13.5 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 GAN04946.1 - 0.044 14.4 0.0 0.051 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 GAN04946.1 - 0.048 13.4 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 GAN04946.1 - 0.052 12.6 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_3 PF07859.13 GAN04946.1 - 0.055 13.3 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAN04946.1 - 0.07 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 GAN04946.1 - 0.071 12.7 0.0 0.78 9.2 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 GAN04946.1 - 0.094 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 GAN04946.1 - 0.12 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HNH_repeat PF18780.1 GAN04946.1 - 0.21 11.4 0.9 0.41 10.5 0.9 1.5 1 0 0 1 1 1 0 Homing endonuclease repeat DUF3245 PF11595.8 GAN04947.1 - 1.1e-10 42.1 8.7 2.4e-10 41.1 7.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) G-patch_2 PF12656.7 GAN04947.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.5 3 0 0 3 3 3 0 G-patch domain PBP1_TM PF14812.6 GAN04947.1 - 0.82 10.1 6.3 1.2 9.6 1.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thg1C PF14413.6 GAN04947.1 - 0.86 9.8 5.9 0.081 13.1 1.0 1.7 2 0 0 2 2 2 0 Thg1 C terminal domain RhoGEF PF00621.20 GAN04948.1 - 4.5e-08 33.6 3.8 1.3e-07 32.0 3.8 1.8 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAN04948.1 - 7.4e-05 23.2 4.3 0.0021 18.5 0.1 3.0 3 0 0 3 3 3 2 PH domain Ran_BP1 PF00638.18 GAN04948.1 - 0.007 16.6 2.1 0.37 11.1 0.7 2.5 2 0 0 2 2 2 2 RanBP1 domain DUF2207 PF09972.9 GAN04949.1 - 0.044 12.6 0.4 0.062 12.1 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Lectin_C PF00059.21 GAN04949.1 - 0.047 14.4 0.1 0.29 11.9 0.1 2.0 1 1 1 2 2 2 0 Lectin C-type domain Pribosyltran PF00156.27 GAN04950.1 - 5.8e-22 77.9 0.0 7.5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 GAN04950.1 - 0.021 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 GAN04950.1 - 0.059 12.8 0.1 0.12 11.8 0.1 1.6 1 1 1 2 2 2 0 Uracil phosphoribosyltransferase HMG_box PF00505.19 GAN04951.1 - 1.9e-19 69.8 1.7 4.4e-19 68.7 1.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN04951.1 - 3e-09 37.3 0.6 3e-09 37.3 0.6 2.0 2 0 0 2 2 2 1 HMG-box domain FMO-like PF00743.19 GAN04952.1 - 1.6e-38 132.4 0.1 8.3e-24 83.9 0.0 3.7 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAN04952.1 - 8.3e-21 74.5 0.8 3.6e-16 59.3 0.4 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAN04952.1 - 2.7e-15 56.4 0.0 6.5e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAN04952.1 - 1.3e-09 37.7 0.4 6.6e-08 32.1 0.1 2.8 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAN04952.1 - 8.3e-06 25.9 0.4 0.044 13.8 0.0 3.9 4 1 0 4 4 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAN04952.1 - 3.8e-05 23.8 0.0 8.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAN04952.1 - 5.3e-05 22.6 0.1 0.0001 21.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAN04952.1 - 0.00014 21.2 0.0 0.00067 19.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAN04952.1 - 0.00018 21.2 0.7 0.1 12.2 0.0 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 GAN04952.1 - 0.0002 21.4 0.0 0.32 11.1 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 GAN04952.1 - 0.0016 17.3 0.1 0.0045 15.7 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 GAN04952.1 - 0.0018 18.7 0.2 0.57 10.6 0.1 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 GAN04952.1 - 0.015 15.2 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAN04952.1 - 0.025 15.2 0.0 0.66 10.6 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAN04952.1 - 0.034 13.4 0.0 4.3 6.5 0.0 3.1 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 GAN04952.1 - 0.073 12.4 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAN04952.1 - 0.083 12.3 0.1 2.7 7.3 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAN04952.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 GAN04952.1 - 0.14 12.4 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 GAN04952.1 - 0.21 12.0 0.6 0.63 10.4 0.1 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TauD PF02668.16 GAN04953.1 - 4.2e-28 98.9 0.1 7.3e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Kelch_4 PF13418.6 GAN04953.1 - 7.9e-12 45.0 3.6 0.022 14.8 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN04953.1 - 1.9e-11 43.7 0.6 0.0083 16.1 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 GAN04953.1 - 8.9e-09 35.0 0.2 0.27 11.3 0.0 6.0 7 0 0 7 7 7 2 Kelch motif Kelch_6 PF13964.6 GAN04953.1 - 4.9e-07 29.8 5.2 1.6 9.1 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 GAN04953.1 - 6e-07 29.6 3.1 1.6 9.1 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN04953.1 - 0.00075 19.0 0.2 0.39 10.3 0.0 4.0 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.10 GAN04953.1 - 0.085 12.3 1.0 0.17 11.3 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MccV PF17508.2 GAN04953.1 - 2.1 8.9 4.2 5.7 7.5 0.1 2.6 2 0 0 2 2 2 0 Microcin V bacteriocin AA_permease_2 PF13520.6 GAN04954.1 - 5.2e-70 236.4 42.3 6.3e-70 236.1 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN04954.1 - 1.5e-24 86.5 36.4 2.2e-24 85.9 36.4 1.3 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 GAN04956.1 - 6.1e-88 295.6 0.0 8.4e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GerD PF17898.1 GAN04957.1 - 0.065 13.2 4.2 0.084 12.8 2.6 2.0 1 1 0 1 1 1 0 Spore germination GerD central core domain Orf78 PF06024.12 GAN04957.1 - 5 7.5 0.0 5 7.5 0.0 3.4 4 1 0 4 4 4 0 Orf78 (ac78) zf-CCCH_4 PF18044.1 GAN04958.1 - 6.4e-07 29.0 1.7 1.3e-06 28.0 1.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAN04958.1 - 8.3e-06 25.7 4.4 1.5e-05 24.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAN04958.1 - 0.00014 21.7 1.0 0.00026 20.8 1.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAN04958.1 - 0.0003 21.5 0.2 0.00057 20.5 0.2 1.4 1 0 0 1 1 1 1 Torus domain DUF3570 PF12094.8 GAN04958.1 - 0.044 12.6 1.7 0.085 11.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) zf-CCCH_2 PF14608.6 GAN04958.1 - 0.24 12.0 2.8 0.41 11.2 2.8 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DnaJ PF00226.31 GAN04959.1 - 3.3e-20 72.0 4.5 5.4e-20 71.3 4.5 1.4 1 0 0 1 1 1 1 DnaJ domain PAPS_reduct PF01507.19 GAN04960.1 - 4.2e-45 153.9 0.0 5.6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MMS19_C PF12460.8 GAN04961.1 - 2.8e-94 316.6 14.6 2.8e-94 316.6 14.6 3.6 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 GAN04961.1 - 2.6e-84 282.9 0.6 2.6e-84 282.9 0.6 4.4 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 GAN04961.1 - 0.0012 19.3 0.2 21 5.7 0.0 5.5 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 GAN04961.1 - 0.0015 18.8 1.1 13 6.3 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 GAN04961.1 - 0.0041 17.3 0.0 7.4 7.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat DUF3535 PF12054.8 GAN04961.1 - 0.021 14.1 0.2 0.61 9.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) Ipi1_N PF12333.8 GAN04961.1 - 0.042 14.5 0.5 1 10.0 0.0 3.5 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DUF4704 PF15787.5 GAN04961.1 - 0.18 11.0 6.0 0.07 12.4 0.2 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4704) AAA PF00004.29 GAN04962.1 - 6.8e-41 139.8 0.0 1.5e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAN04962.1 - 9.9e-18 63.9 0.1 1.9e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAN04962.1 - 2.4e-09 36.8 0.2 7.6e-09 35.2 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAN04962.1 - 1.4e-05 25.1 0.1 8.4e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN04962.1 - 1.9e-05 25.1 0.2 0.0059 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAN04962.1 - 0.00019 21.2 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAN04962.1 - 0.00036 20.7 0.0 0.0024 18.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAN04962.1 - 0.00041 20.6 0.3 0.06 13.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GAN04962.1 - 0.0015 17.7 0.0 0.0032 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 GAN04962.1 - 0.0016 18.0 0.1 0.023 14.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 GAN04962.1 - 0.0044 17.2 0.0 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAN04962.1 - 0.0044 16.9 0.2 0.37 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAN04962.1 - 0.0054 16.1 0.1 0.016 14.6 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAN04962.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 GAN04962.1 - 0.053 12.9 0.3 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 GAN04962.1 - 0.055 13.2 0.2 0.24 11.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAN04962.1 - 0.058 14.0 0.1 0.37 11.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 GAN04962.1 - 0.058 12.9 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 GAN04962.1 - 0.062 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAN04962.1 - 0.094 12.4 0.0 0.31 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 GAN04962.1 - 0.14 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TRAF_BIRC3_bd PF16673.5 GAN04962.1 - 0.37 10.6 3.1 0.89 9.4 1.6 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DivIC PF04977.15 GAN04962.1 - 0.48 10.2 2.9 1.5 8.6 2.9 1.9 1 0 0 1 1 1 0 Septum formation initiator FlxA PF14282.6 GAN04962.1 - 2.6 8.1 7.0 0.57 10.2 2.8 2.0 3 0 0 3 3 2 0 FlxA-like protein MTHFR PF02219.17 GAN04963.1 - 5.9e-114 380.2 0.0 7.7e-114 379.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase zf-C2H2_2 PF12756.7 GAN04964.1 - 3.7e-16 59.3 57.9 0.00026 21.3 0.6 11.6 4 1 7 13 13 13 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAN04964.1 - 8.2e-13 48.3 75.6 0.054 13.9 1.1 14.2 14 0 0 14 14 14 9 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN04964.1 - 1.1e-07 32.1 137.0 0.0017 19.1 1.9 15.7 16 0 0 16 16 16 8 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 GAN04964.1 - 3.5e-05 23.3 58.0 2.3 7.9 0.5 13.0 15 0 0 15 15 15 8 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 GAN04964.1 - 3.9e-05 23.8 86.4 0.056 13.7 1.3 13.7 14 0 0 14 14 14 7 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 GAN04964.1 - 0.00051 18.7 63.3 0.6 8.6 0.1 13.3 14 1 1 15 15 15 10 Protein of unknown function (DUF629) DUF5617 PF18493.1 GAN04964.1 - 0.015 15.4 0.0 3.7 7.7 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) DUF1688 PF07958.11 GAN04965.1 - 1.1e-139 465.8 0.0 1.3e-139 465.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) ABC2_membrane PF01061.24 GAN04966.1 - 1.1e-84 283.1 73.2 1.4e-47 161.8 22.4 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAN04966.1 - 1.5e-34 119.4 0.0 4e-18 66.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAN04966.1 - 1.4e-27 95.4 2.4 2.9e-21 75.2 0.0 4.3 5 0 0 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 GAN04966.1 - 5.8e-17 62.1 0.1 1.3e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 GAN04966.1 - 0.00019 21.3 0.2 0.065 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAN04966.1 - 0.00059 19.8 0.1 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 GAN04966.1 - 0.00062 19.0 26.5 0.00062 19.0 26.5 4.0 2 2 2 4 4 4 1 ABC-2 family transporter protein AAA_16 PF13191.6 GAN04966.1 - 0.0013 19.2 0.1 0.06 13.7 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 GAN04966.1 - 0.0021 18.3 0.0 0.48 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAN04966.1 - 0.0032 17.9 0.0 5.2 7.5 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAN04966.1 - 0.0071 16.9 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAN04966.1 - 0.0076 15.8 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAN04966.1 - 0.011 15.5 0.3 0.061 13.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DnaB_C PF03796.15 GAN04966.1 - 0.022 14.1 0.0 0.62 9.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 GAN04966.1 - 0.059 13.1 0.7 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF4294 PF14127.6 GAN04966.1 - 0.12 12.3 0.8 9.7 6.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) TsaE PF02367.17 GAN04966.1 - 0.15 12.0 0.6 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAN04966.1 - 0.19 12.0 0.8 2.1 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 GAN04966.1 - 0.26 11.2 0.7 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain ABC2_membrane PF01061.24 GAN04967.1 - 4.1e-84 281.2 53.4 2.7e-47 160.9 18.9 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAN04967.1 - 2e-36 125.5 0.2 1.8e-19 70.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 GAN04967.1 - 8.1e-33 112.2 5.7 2.7e-24 84.9 0.3 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAN04967.1 - 3.1e-15 56.5 0.0 6.6e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 GAN04967.1 - 4.1e-06 27.3 0.0 0.005 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 GAN04967.1 - 7.3e-05 22.0 58.9 0.001 18.3 16.9 3.6 2 2 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAN04967.1 - 0.00014 21.8 0.2 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 GAN04967.1 - 0.00037 20.4 0.0 0.15 11.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 GAN04967.1 - 0.0024 18.0 0.3 0.51 10.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAN04967.1 - 0.0029 18.2 0.0 0.12 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAN04967.1 - 0.0052 17.1 0.1 0.92 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAN04967.1 - 0.013 15.1 0.1 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 GAN04967.1 - 0.016 15.3 0.9 7.1 6.7 0.1 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_25 PF13481.6 GAN04967.1 - 0.019 14.5 0.1 0.099 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAN04967.1 - 0.027 14.2 0.3 2.3 7.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAN04967.1 - 0.056 13.2 0.1 0.056 13.2 0.1 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA PF00004.29 GAN04967.1 - 0.11 12.9 0.4 17 5.9 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAN04967.1 - 0.15 12.0 0.2 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 GAN04967.1 - 0.22 11.7 0.8 0.98 9.6 0.2 2.2 2 0 0 2 2 2 0 AAA domain UcrQ PF02939.16 GAN04968.1 - 8.1e-33 112.2 0.5 9.1e-33 112.0 0.5 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 GAN04968.1 - 0.028 14.8 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Phage_holin_8 PF16931.5 GAN04968.1 - 0.082 12.9 0.7 0.097 12.6 0.7 1.1 1 0 0 1 1 1 0 Putative phage holin zf-RING_4 PF14570.6 GAN04969.1 - 7.4e-23 80.1 12.2 1.5e-22 79.1 12.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GAN04969.1 - 1.8e-07 30.9 8.6 1.8e-07 30.9 8.6 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 GAN04969.1 - 2.3e-05 24.1 0.0 6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 GAN04969.1 - 9.5e-05 22.2 9.3 0.0039 17.0 9.5 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN04969.1 - 0.00093 19.5 11.8 0.0021 18.3 11.8 1.6 1 0 0 1 1 1 1 Ring finger domain Nup35_RRM_2 PF14605.6 GAN04969.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 GAN04969.1 - 0.023 14.5 11.0 0.05 13.5 11.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 GAN04969.1 - 0.047 13.6 2.9 0.1 12.6 2.9 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 GAN04969.1 - 0.069 13.0 11.1 0.15 11.9 11.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN04969.1 - 0.14 12.3 6.5 0.31 11.1 5.4 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.6 GAN04969.1 - 0.52 10.5 7.2 0.077 13.1 2.8 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF5385 PF17359.2 GAN04969.1 - 8.3 5.9 11.2 0.21 11.1 2.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DIOX_N PF14226.6 GAN04970.1 - 3.8e-35 121.2 0.0 5.9e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAN04970.1 - 4.7e-17 62.3 0.0 9.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LIN52 PF10044.9 GAN04970.1 - 0.1 13.3 0.0 0.43 11.3 0.0 2.0 2 0 0 2 2 2 0 Retinal tissue protein Ribophorin_I PF04597.14 GAN04971.1 - 1.8e-137 459.1 7.3 2.1e-137 458.9 7.3 1.0 1 0 0 1 1 1 1 Ribophorin I DUF2204 PF09970.9 GAN04971.1 - 0.043 13.5 0.5 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) DUF2664 PF10867.8 GAN04971.1 - 0.056 13.9 0.2 0.38 11.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) eIF2_C PF09173.11 GAN04972.1 - 7.5e-34 115.8 1.4 1.7e-33 114.7 0.4 2.1 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GAN04972.1 - 3.1e-23 82.3 1.2 2.4e-22 79.4 1.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAN04972.1 - 4.1e-08 33.5 3.3 4.5e-08 33.4 1.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 GAN04972.1 - 0.00059 19.8 0.6 0.0084 16.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAN04972.1 - 0.0022 18.1 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 GAN04972.1 - 0.0095 15.9 0.1 0.024 14.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 GAN04972.1 - 0.069 13.2 0.2 0.2 11.7 0.2 2.0 1 1 0 1 1 1 0 Dynamin family DEAD PF00270.29 GAN04973.1 - 1.4e-49 168.3 0.0 2.3e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN04973.1 - 1.5e-31 109.0 0.0 8e-31 106.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN04973.1 - 1.4e-05 25.1 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAN04973.1 - 0.11 11.2 0.0 0.24 10.1 0.0 1.5 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 GAN04973.1 - 0.12 12.7 0.1 0.88 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 GAN04973.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3472 PF11958.8 GAN04974.1 - 3e-24 86.4 2.8 4.4e-24 85.9 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 GAN04974.1 - 2.3e-11 44.0 0.1 4.5e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) BNR PF02012.20 GAN04974.1 - 0.0029 17.4 0.1 0.012 15.5 0.1 2.2 1 0 0 1 1 1 1 BNR/Asp-box repeat Vps51 PF08700.11 GAN04975.1 - 2.1e-26 91.8 2.7 5.1e-26 90.6 1.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 GAN04975.1 - 2.4e-21 76.4 3.1 2.4e-21 76.4 3.1 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 GAN04975.1 - 7.8e-13 47.8 0.7 7.8e-13 47.8 0.7 1.9 2 0 0 2 2 2 1 Dor1-like family Vps54_N PF10475.9 GAN04975.1 - 4.1e-11 42.7 1.6 8.4e-11 41.7 1.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 GAN04975.1 - 1.8e-06 28.1 0.4 1.8e-06 28.1 0.4 3.0 3 0 0 3 3 2 1 Golgi transport complex subunit 5 Vps53_N PF04100.12 GAN04975.1 - 5.3e-06 25.7 1.5 5.3e-06 25.7 1.5 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal COG2 PF06148.11 GAN04975.1 - 1.3e-05 25.3 4.4 0.0001 22.4 0.2 3.3 5 0 0 5 5 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 GAN04975.1 - 2.4e-05 23.1 2.0 4.6e-05 22.2 2.0 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 CENP-F_leu_zip PF10473.9 GAN04975.1 - 0.00054 20.0 2.0 0.00054 20.0 2.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 GAN04975.1 - 0.0015 18.7 3.5 0.0021 18.3 1.1 2.5 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding GAS PF13851.6 GAN04975.1 - 0.0075 15.6 1.3 0.021 14.2 1.3 1.7 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding PI3K_P85_iSH2 PF16454.5 GAN04975.1 - 0.0088 15.6 2.9 0.037 13.6 1.5 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Laminin_II PF06009.12 GAN04975.1 - 0.029 14.4 0.7 0.2 11.7 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II Nsp1_C PF05064.13 GAN04975.1 - 0.075 12.8 1.5 0.27 11.1 1.5 1.9 1 0 0 1 1 1 0 Nsp1-like C-terminal region Prefoldin PF02996.17 GAN04975.1 - 0.11 12.4 1.2 0.45 10.4 0.6 2.3 2 0 0 2 2 2 0 Prefoldin subunit RPAP1_N PF08621.10 GAN04975.1 - 0.18 11.6 2.5 0.29 10.9 0.4 2.4 2 0 0 2 2 2 0 RPAP1-like, N-terminal BLOC1_2 PF10046.9 GAN04975.1 - 0.18 12.1 2.4 1.4 9.2 2.3 2.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4988 PF16378.5 GAN04975.1 - 0.27 10.9 1.8 0.92 9.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function Sec8_exocyst PF04048.14 GAN04975.1 - 0.46 10.4 6.8 0.12 12.2 2.4 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain YabA PF06156.13 GAN04975.1 - 1 10.0 3.8 4.5 8.0 2.5 2.7 1 1 1 2 2 2 0 Initiation control protein YabA DUF5082 PF16888.5 GAN04975.1 - 1.4 9.2 8.9 17 5.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) BRE1 PF08647.11 GAN04975.1 - 2.1 8.4 9.8 0.25 11.4 3.5 2.6 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 GAN04975.1 - 4.3 7.5 7.8 2.7 8.2 2.6 3.4 5 0 0 5 5 4 0 Fibrinogen alpha/beta chain family LysM PF01476.20 GAN04977.1 - 1.6e-09 37.7 0.0 0.0001 22.3 0.0 2.6 2 0 0 2 2 2 2 LysM domain DUF913 PF06025.12 GAN04977.1 - 0.0022 17.0 4.0 0.0028 16.7 4.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) HTH_Tnp_1 PF01527.20 GAN04977.1 - 0.0059 16.9 1.4 0.36 11.2 0.0 2.7 3 0 0 3 3 2 1 Transposase HTH_23 PF13384.6 GAN04977.1 - 0.012 15.3 0.1 0.23 11.3 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.6 GAN04977.1 - 0.013 15.6 0.1 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain NARP1 PF12569.8 GAN04977.1 - 0.028 13.3 6.0 0.032 13.1 6.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PP_M1 PF03012.14 GAN04977.1 - 0.049 13.2 6.3 0.065 12.8 6.3 1.2 1 0 0 1 1 1 0 Phosphoprotein GREB1 PF15782.5 GAN04977.1 - 0.15 9.1 4.7 0.15 9.2 4.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 GAN04977.1 - 0.22 11.3 6.9 0.24 11.2 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2252 PF10009.9 GAN04977.1 - 0.23 10.5 3.4 0.39 9.7 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Dicty_REP PF05086.12 GAN04977.1 - 0.27 9.1 11.5 0.32 8.9 11.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CPSF100_C PF13299.6 GAN04977.1 - 0.35 11.1 6.4 0.48 10.6 6.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3807 PF12720.7 GAN04977.1 - 0.4 10.9 10.6 0.58 10.4 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PPL5 PF18168.1 GAN04977.1 - 0.69 9.2 5.7 0.9 8.8 5.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_Rpc4 PF05132.14 GAN04977.1 - 0.76 10.2 9.2 1.1 9.7 9.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CNDH2_M PF16869.5 GAN04977.1 - 0.78 10.4 4.5 1.2 9.8 4.5 1.4 1 0 0 1 1 1 0 PF16858 Mucin PF01456.17 GAN04977.1 - 0.79 9.7 21.2 0.11 12.5 17.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Sec62 PF03839.16 GAN04977.1 - 1.6 8.2 10.0 2.2 7.7 10.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 GAN04977.1 - 2.3 6.9 6.9 2.9 6.6 6.9 1.1 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 GAN04977.1 - 8.1 6.3 14.6 12 5.6 14.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus Peptidase_S49_N PF08496.10 GAN04977.1 - 9.6 6.2 12.6 17 5.4 12.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YhhN PF07947.14 GAN04978.1 - 9.9e-38 129.6 10.9 1.3e-37 129.2 10.9 1.1 1 0 0 1 1 1 1 YhhN family SelR PF01641.18 GAN04980.1 - 8.4e-52 174.4 0.2 1e-51 174.1 0.2 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 GAN04980.1 - 0.018 15.2 0.6 0.048 13.9 0.6 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 GAN04980.1 - 0.024 14.4 0.2 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HAD PF12710.7 GAN04981.1 - 9.9e-17 61.9 0.0 2.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN04981.1 - 6.8e-14 52.7 0.3 1.3e-13 51.7 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN04981.1 - 3.9e-09 36.6 3.8 6.8e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 GAN04981.1 - 6.2e-08 32.5 0.0 1.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain SPX PF03105.19 GAN04981.1 - 0.00041 20.4 0.1 0.00041 20.4 0.1 2.8 2 1 2 4 4 4 1 SPX domain Put_Phosphatase PF06888.12 GAN04981.1 - 0.00072 19.0 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.12 GAN04981.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF2710 PF10921.8 GAN04981.1 - 0.056 13.9 0.2 0.4 11.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2710) HAD_2 PF13419.6 GAN04981.1 - 0.065 13.3 0.3 8.2 6.5 0.1 3.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 GAN04982.1 - 5.5e-52 176.7 0.0 9.2e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04982.1 - 2.9e-20 72.6 0.1 1.1e-19 70.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAN04982.1 - 0.00092 19.2 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN04982.1 - 0.0026 17.1 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 GAN04982.1 - 0.07 12.7 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 GAN04982.1 - 0.094 12.1 0.5 0.31 10.3 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NACHT PF05729.12 GAN04983.1 - 0.034 14.0 0.5 0.083 12.8 0.5 1.6 1 0 0 1 1 1 0 NACHT domain ELM2 PF01448.24 GAN04983.1 - 9.7 7.0 6.8 4.3 8.2 0.0 3.5 2 1 0 2 2 2 0 ELM2 domain TEA PF01285.18 GAN04984.1 - 3.4e-31 107.1 0.0 8e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain YBD PF17725.1 GAN04984.1 - 7.5e-07 29.2 2.1 1.7e-06 28.1 2.1 1.5 1 0 0 1 1 1 1 YAP binding domain CLASP_N PF12348.8 GAN04985.1 - 1e-54 185.5 0.8 1.7e-54 184.8 0.8 1.4 1 0 0 1 1 1 1 CLASP N terminal IBN_N PF03810.19 GAN04985.1 - 0.026 14.4 0.1 0.084 12.8 0.1 1.9 1 0 0 1 1 1 0 Importin-beta N-terminal domain V-SNARE PF05008.15 GAN04986.1 - 1.5e-23 82.9 7.2 6.5e-23 80.9 3.7 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GAN04986.1 - 1.4e-19 70.1 3.7 3.2e-19 69.0 3.1 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 GAN04986.1 - 6.9e-05 22.8 0.9 0.00018 21.4 0.9 1.7 1 0 0 1 1 1 1 SNARE domain DUF4407 PF14362.6 GAN04986.1 - 0.004 16.6 3.1 0.0053 16.2 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Fusion_gly PF00523.18 GAN04986.1 - 0.0079 14.5 1.5 0.011 14.0 0.8 1.5 2 0 0 2 2 2 1 Fusion glycoprotein F0 Lant_dehydr_C PF14028.6 GAN04986.1 - 0.054 13.0 0.4 0.17 11.4 0.1 1.8 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term RIFIN PF02009.16 GAN04986.1 - 0.065 13.1 0.9 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Rifin Sec20 PF03908.13 GAN04986.1 - 0.13 12.2 1.6 0.23 11.4 0.2 2.2 2 1 0 2 2 2 0 Sec20 EspB PF05802.11 GAN04986.1 - 0.5 10.3 5.1 0.92 9.5 4.6 1.8 1 1 0 1 1 1 0 Enterobacterial EspB protein Synaptobrevin PF00957.21 GAN04986.1 - 6.8 6.6 7.6 0.98 9.3 0.4 2.9 4 0 0 4 4 4 0 Synaptobrevin Rad51 PF08423.11 GAN04987.1 - 3.1e-123 410.0 0.1 3.9e-123 409.7 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 GAN04987.1 - 1.5e-09 37.7 0.1 2.2e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 GAN04987.1 - 4.1e-09 36.3 0.0 6.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAN04987.1 - 4.4e-07 29.5 0.5 8.3e-07 28.6 0.0 1.9 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.6 GAN04987.1 - 3.5e-05 24.3 0.2 8.8e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 GAN04987.1 - 0.0006 19.2 0.1 0.027 13.8 0.1 2.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain DUF3827 PF12877.7 GAN04987.1 - 0.037 12.4 3.9 0.047 12.1 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) AAA_22 PF13401.6 GAN04987.1 - 0.094 13.0 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 GAN04987.1 - 1.8 7.7 7.3 0.2 10.8 0.2 2.6 3 0 0 3 3 3 0 PAXNEB protein Zn_clus PF00172.18 GAN04988.1 - 9.4e-10 38.5 13.4 9.4e-10 38.5 13.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bestrophin PF01062.21 GAN04989.1 - 6.4e-39 134.1 0.0 3.9e-24 85.6 0.0 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4239 PF14023.6 GAN04989.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) GRDP-like PF07173.12 GAN04991.1 - 0.00045 20.9 7.0 0.0021 18.7 0.5 3.5 2 1 1 3 3 3 1 Glycine-rich domain-containing protein-like FYVE PF01363.21 GAN04991.1 - 0.084 13.0 1.1 2.1 8.6 0.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger Moricin PF06451.11 GAN04992.1 - 0.015 15.1 1.6 0.14 12.0 0.1 2.4 2 0 0 2 2 2 0 Moricin DUF4758 PF15950.5 GAN04992.1 - 0.048 14.0 1.3 0.057 13.7 1.3 1.1 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein DUF4834 PF16118.5 GAN04994.1 - 4 8.5 7.0 1.3 10.0 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FHA PF00498.26 GAN04996.1 - 2.2e-15 56.8 0.6 2.2e-15 56.8 0.6 1.9 2 0 0 2 2 1 1 FHA domain zf-RING_11 PF17123.5 GAN04996.1 - 1.2e-10 41.0 7.1 1.2e-10 41.0 7.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 GAN04996.1 - 8.3e-08 32.4 7.5 1.7e-07 31.4 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN04996.1 - 0.00048 19.9 8.4 0.00095 19.0 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN04996.1 - 0.0007 19.4 6.7 0.0014 18.4 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN04996.1 - 0.0012 18.8 6.7 0.0025 17.7 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 GAN04996.1 - 0.0023 18.2 0.2 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 GAN04996.1 - 0.0036 17.6 7.0 0.0091 16.3 7.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAN04996.1 - 0.009 15.9 4.0 0.017 15.0 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN04996.1 - 0.025 14.6 8.5 0.056 13.5 8.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 GAN04996.1 - 0.066 13.1 3.7 0.16 11.9 3.7 1.7 1 0 0 1 1 1 0 PHD-finger TF_Zn_Ribbon PF08271.12 GAN04996.1 - 0.26 10.8 1.8 3.3 7.3 0.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ANAPC11 PF12861.7 GAN04996.1 - 0.37 10.9 2.0 0.89 9.6 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pkinase PF00069.25 GAN04997.1 - 4.2e-61 206.6 0.0 2.2e-60 204.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN04997.1 - 1.5e-28 99.8 0.0 8.8e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN04997.1 - 2.7e-06 26.6 0.3 4.1e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN04997.1 - 0.00073 18.9 1.9 0.04 13.2 0.9 3.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAN04997.1 - 0.0026 17.2 0.1 0.0074 15.7 0.0 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN04997.1 - 0.0031 17.5 0.3 0.045 13.7 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAN04997.1 - 0.02 14.0 0.1 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 GAN04997.1 - 0.065 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dynamin_M PF01031.20 GAN04998.1 - 1.3e-109 365.9 0.3 1.2e-108 362.7 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region Porphobil_deam PF01379.20 GAN04998.1 - 4.2e-67 225.6 0.0 1.1e-66 224.3 0.0 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Dynamin_N PF00350.23 GAN04998.1 - 1.5e-54 184.6 0.0 4.1e-54 183.1 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAN04998.1 - 2.3e-32 111.0 4.2 2.3e-32 111.0 4.2 2.3 1 1 1 2 2 2 1 Dynamin GTPase effector domain Porphobil_deamC PF03900.15 GAN04998.1 - 1.4e-18 67.0 0.1 3.8e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain MMR_HSR1 PF01926.23 GAN04998.1 - 0.00022 21.3 0.0 0.0011 19.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAN04998.1 - 0.036 14.5 0.3 0.34 11.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain SWI2_SNF2 PF18766.1 GAN04998.1 - 0.059 13.0 0.5 0.12 12.0 0.5 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_15 PF13175.6 GAN04998.1 - 0.12 12.1 4.7 0.87 9.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain TauD PF02668.16 GAN04999.1 - 1.4e-55 189.0 0.7 1.7e-55 188.7 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RrnaAD PF00398.20 GAN05000.1 - 3.9e-46 157.3 0.1 4.4e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAN05000.1 - 0.0014 19.3 0.0 0.0033 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 GAN05000.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 GAN05000.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain BRO1 PF03097.18 GAN05001.1 - 1.9e-27 96.1 2.9 2.5e-27 95.7 2.9 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 GAN05001.1 - 0.0029 16.7 7.5 0.014 14.4 4.0 3.0 3 1 1 4 4 4 1 Family of unknown function (DUF5355) ENTH PF01417.20 GAN05001.1 - 0.068 13.2 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 ENTH domain Peptidase_C10 PF01640.17 GAN05001.1 - 0.28 11.5 1.4 0.99 9.7 0.2 2.3 2 1 0 2 2 2 0 Peptidase C10 family Sugar_tr PF00083.24 GAN05002.1 - 3.7e-102 342.5 26.2 1.6e-51 175.6 4.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN05002.1 - 3e-26 92.2 37.3 4.6e-18 65.3 8.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Phyto_Pns9_10 PF05878.11 GAN05003.1 - 0.052 12.7 0.2 0.056 12.6 0.2 1.0 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 RabGAP-TBC PF00566.18 GAN05004.1 - 9.9e-56 188.8 0.4 9.9e-56 188.8 0.4 3.0 4 0 0 4 4 4 1 Rab-GTPase-TBC domain Jnk-SapK_ap_N PF09744.9 GAN05004.1 - 0.017 15.4 14.7 0.017 15.4 14.7 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 ComZ PF10815.8 GAN05004.1 - 0.025 14.6 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 ComZ HALZ PF02183.18 GAN05004.1 - 0.042 14.1 13.4 3.6 7.9 0.2 4.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper bVLRF1 PF18826.1 GAN05004.1 - 0.74 9.7 4.4 1.6 8.5 4.4 1.5 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor UPF0242 PF06785.11 GAN05004.1 - 2.5 8.2 19.7 1.2 9.2 16.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 GAN05004.1 - 9.3 6.3 28.2 8.5 6.4 22.7 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lipase_3 PF01764.25 GAN05005.1 - 7.7e-10 38.8 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAN05005.1 - 0.0024 17.2 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 GAN05005.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 GAN05005.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 GAN05005.1 - 0.036 13.8 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 GAN05005.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.18 GAN05006.1 - 1.6e-06 28.1 10.4 1.6e-06 28.1 10.4 1.8 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SprA-related PF12118.8 GAN05006.1 - 0.027 13.6 12.6 0.04 13.1 12.6 1.1 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.13 GAN05006.1 - 0.17 11.8 17.7 0.22 11.5 17.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAN05006.1 - 4.1 6.1 5.9 5.1 5.7 5.9 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 GAN05006.1 - 6 6.4 25.4 3.2 7.3 22.9 1.7 2 0 0 2 2 2 0 Spt20 family CLP_protease PF00574.23 GAN05007.1 - 7.1e-83 277.0 0.0 8.6e-83 276.7 0.0 1.0 1 0 0 1 1 1 1 Clp protease SpoOE-like PF09388.10 GAN05007.1 - 0.16 11.9 1.1 0.33 10.9 1.1 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein PNRC PF15365.6 GAN05007.1 - 0.18 11.6 0.2 0.38 10.6 0.2 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Iso_dh PF00180.20 GAN05008.1 - 3.9e-79 266.3 0.0 4.7e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YvrJ PF12841.7 GAN05009.1 - 0.52 9.9 6.2 8.7 6.0 1.4 2.5 2 0 0 2 2 2 0 YvrJ protein family Nse4_C PF08743.10 GAN05010.1 - 9e-23 80.4 2.3 1e-22 80.2 0.2 2.3 2 0 0 2 2 2 1 Nse4 C-terminal IBN_N PF03810.19 GAN05010.1 - 1.2e-14 53.9 0.0 1e-13 51.0 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Nse4-Nse3_bdg PF15412.6 GAN05010.1 - 0.00023 21.2 0.0 0.0007 19.7 0.0 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Xpo1 PF08389.12 GAN05010.1 - 0.00024 21.2 2.5 0.00034 20.7 0.3 2.5 2 0 0 2 2 2 1 Exportin 1-like protein DUF3385 PF11865.8 GAN05010.1 - 0.011 15.6 8.0 0.032 14.2 0.2 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 GAN05010.1 - 0.075 13.4 0.1 0.41 11.1 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats ABC1 PF03109.16 GAN05011.1 - 6.3e-33 113.5 0.0 1.8e-32 112.0 0.0 1.8 2 0 0 2 2 2 1 ABC1 family F-box-like PF12937.7 GAN05012.1 - 0.0015 18.4 0.1 0.0025 17.7 0.1 1.5 1 1 0 1 1 1 1 F-box-like SART-1 PF03343.13 GAN05013.1 - 9.4e-153 510.1 86.2 1.1e-152 509.9 86.2 1.0 1 0 0 1 1 1 1 SART-1 family RhoGEF PF00621.20 GAN05014.1 - 3.6e-16 59.9 1.4 6.7e-16 59.0 1.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAN05014.1 - 0.00023 21.6 0.3 0.0021 18.5 0.3 2.4 1 1 0 1 1 1 1 PH domain Myosin_head PF00063.21 GAN05015.1 - 2.9e-14 52.3 1.0 3.1e-14 52.2 1.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) RIO1 PF01163.22 GAN05016.1 - 1.5e-73 246.4 1.7 1.5e-73 246.4 1.7 1.6 2 0 0 2 2 2 1 RIO1 family CDC45 PF02724.14 GAN05016.1 - 0.00044 18.7 15.2 0.00044 18.7 15.2 1.7 2 0 0 2 2 2 1 CDC45-like protein APH PF01636.23 GAN05016.1 - 0.062 13.2 1.8 7.3 6.4 0.0 2.9 4 0 0 4 4 4 0 Phosphotransferase enzyme family Mt_ATP-synt_B PF05405.14 GAN05016.1 - 0.22 11.1 0.1 0.22 11.1 0.1 2.2 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Hid1 PF12722.7 GAN05016.1 - 0.91 7.6 8.1 1.4 6.9 8.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YL1 PF05764.13 GAN05016.1 - 5.6 7.0 40.9 0.48 10.5 27.2 2.4 2 0 0 2 2 2 0 YL1 nuclear protein HSP90 PF00183.18 GAN05018.1 - 2.8e-174 580.9 8.6 4.1e-174 580.3 8.6 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAN05018.1 - 2.5e-11 44.1 0.0 7.1e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAN05018.1 - 2.4e-10 40.4 0.0 7.6e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1198 PF06711.11 GAN05018.1 - 0.13 12.3 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Peptidase_M50B PF13398.6 GAN05019.1 - 6.5e-55 185.9 19.5 9e-55 185.4 19.5 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF92 PF01940.16 GAN05019.1 - 6.3 6.1 12.2 0.69 9.3 0.1 2.6 2 1 0 2 2 2 0 Integral membrane protein DUF92 Ndc1_Nup PF09531.10 GAN05019.1 - 6.8 5.3 8.5 10 4.7 8.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-CCHC PF00098.23 GAN05022.1 - 3.4e-06 26.9 10.0 0.0031 17.5 0.9 2.7 3 0 0 3 3 3 2 Zinc knuckle zf-C2H2_10 PF16588.5 GAN05022.1 - 0.0007 19.3 2.1 0.0007 19.3 2.1 2.8 3 0 0 3 3 3 2 C2H2 zinc-finger zf-CCHC_4 PF14392.6 GAN05022.1 - 0.0022 17.7 8.9 0.009 15.7 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-nanos PF05741.13 GAN05022.1 - 0.06 13.6 6.7 0.38 11.0 6.7 2.1 1 1 0 1 1 1 0 Nanos RNA binding domain zf-CCHC_2 PF13696.6 GAN05022.1 - 4 7.4 10.4 0.42 10.5 2.1 2.5 2 0 0 2 2 2 0 Zinc knuckle XLF PF09302.11 GAN05024.1 - 3.1e-12 47.0 0.9 4.4e-12 46.5 0.5 1.5 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component QRPTase_C PF01729.19 GAN05025.1 - 2.4e-57 193.4 0.1 2.9e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GAN05025.1 - 1.2e-19 70.1 0.0 2.6e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Trimer_CC PF08954.11 GAN05026.1 - 0.13 11.8 2.5 3.8 7.1 0.2 3.2 2 0 0 2 2 2 0 Trimerisation motif TSC22 PF01166.18 GAN05026.1 - 0.27 11.6 23.5 1 9.7 0.2 5.2 4 1 1 5 5 5 0 TSC-22/dip/bun family Y_phosphatase3 PF13350.6 GAN05026.1 - 0.39 10.6 4.1 0.32 10.9 0.9 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF641 PF04859.12 GAN05026.1 - 1.6 9.1 22.7 2.2 8.6 6.5 4.0 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Filament PF00038.21 GAN05026.1 - 1.9 8.0 31.3 1.8 8.1 12.1 3.2 3 0 0 3 3 3 0 Intermediate filament protein RBD-FIP PF09457.10 GAN05026.1 - 5.5 7.0 11.5 0.1 12.6 0.9 3.2 3 0 0 3 3 3 0 FIP domain YabA PF06156.13 GAN05026.1 - 6.6 7.4 34.6 0.11 13.2 3.4 4.6 3 2 1 4 4 4 0 Initiation control protein YabA Lebercilin PF15619.6 GAN05026.1 - 7.3 6.2 37.0 4.9 6.8 3.5 3.5 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Lectin_C PF00059.21 GAN05027.1 - 0.0086 16.8 1.5 0.067 13.9 0.3 2.4 2 0 0 2 2 2 1 Lectin C-type domain adh_short PF00106.25 GAN05028.1 - 1.2e-38 132.5 1.0 1.5e-38 132.2 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN05028.1 - 1.9e-26 93.0 0.1 2.7e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAN05028.1 - 0.00029 20.4 0.1 0.0013 18.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAN05028.1 - 0.00041 20.3 0.2 0.00056 19.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAN05028.1 - 0.035 14.4 0.1 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 GAN05028.1 - 0.06 12.5 0.3 0.083 12.0 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAN05028.1 - 0.07 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Pkinase PF00069.25 GAN05029.1 - 1.9e-54 184.8 0.5 4e-54 183.8 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05029.1 - 8.9e-40 136.6 0.3 1.4e-39 135.9 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 GAN05029.1 - 5.6e-05 23.3 0.2 0.00014 22.0 0.2 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain MerR_2 PF13591.6 GAN05029.1 - 0.009 15.8 0.7 0.03 14.2 0.1 2.2 2 0 0 2 2 2 1 MerR HTH family regulatory protein APH PF01636.23 GAN05029.1 - 0.011 15.6 0.1 3.8 7.4 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family GH114_assoc PF14741.6 GAN05029.1 - 0.017 15.3 0.2 0.16 12.2 0.1 2.4 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain DUF4373 PF14297.6 GAN05029.1 - 0.095 13.5 1.4 13 6.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4373) ADIP PF11559.8 GAN05029.1 - 2.9 7.9 15.0 0.046 13.8 7.5 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding RNB PF00773.19 GAN05030.1 - 1.8e-104 349.6 0.1 1.8e-104 349.6 0.1 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 GAN05030.1 - 3.9e-23 81.3 0.0 8.5e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 GAN05030.1 - 5.3e-16 58.7 0.0 5.3e-16 58.7 0.0 3.5 6 0 0 6 6 6 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 GAN05030.1 - 2.9e-07 30.3 0.1 1.3e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 GAN05030.1 - 7.9e-07 29.2 0.1 0.013 15.7 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 GAN05030.1 - 0.00067 19.3 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain CRAL_TRIO_N PF03765.15 GAN05031.1 - 3.4e-09 36.7 0.1 7.5e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 GAN05032.1 - 3.2e-38 130.9 0.1 3.9e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAN05032.1 - 2.2e-08 34.3 0.0 3.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3914 PF13053.6 GAN05033.1 - 0.092 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Spt5_N PF11942.8 GAN05034.1 - 0.027 15.5 3.8 0.27 12.2 0.0 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 GAN05034.1 - 3.3 8.1 5.8 0.81 10.1 0.9 2.3 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thiol_cytolys_C PF17440.2 GAN05035.1 - 0.033 14.4 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Thiol-activated cytolysin beta sandwich domain Methyltransf_25 PF13649.6 GAN05036.1 - 1.3e-15 57.8 0.0 5.1e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05036.1 - 1.3e-13 51.4 0.0 2.7e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN05036.1 - 1.6e-13 50.7 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05036.1 - 1.3e-11 44.6 0.0 1.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05036.1 - 5.6e-08 32.4 0.0 9.7e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN05036.1 - 2.8e-06 26.9 0.0 5.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAN05036.1 - 1.7e-05 25.5 0.0 3.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAN05036.1 - 0.0006 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 GAN05036.1 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 GAN05036.1 - 0.0038 16.8 0.0 0.024 14.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 GAN05036.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAN05036.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 GAN05036.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_9 PF08003.11 GAN05036.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NNMT_PNMT_TEMT PF01234.17 GAN05036.1 - 0.11 11.7 0.0 0.78 8.9 0.0 2.0 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family FtsJ PF01728.19 GAN05036.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ribosomal_L34 PF00468.17 GAN05038.1 - 4.1e-21 74.7 6.6 5.6e-21 74.2 6.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 Dus PF01207.17 GAN05039.1 - 2.6e-51 174.6 0.0 3.7e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAN05039.1 - 0.00013 21.5 0.0 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein MCR_C PF04609.12 GAN05039.1 - 0.11 11.5 0.1 0.28 10.2 0.1 1.6 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Methyltransf_31 PF13847.6 GAN05040.1 - 5.2e-16 58.8 0.1 8.4e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05040.1 - 6.6e-14 52.3 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN05040.1 - 6.8e-14 52.3 0.1 2.1e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05040.1 - 3e-13 49.9 0.2 5.5e-13 49.1 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN05040.1 - 1e-12 48.6 1.2 2.6e-12 47.4 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 GAN05040.1 - 8.2e-07 28.8 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 GAN05040.1 - 0.00034 20.0 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 GAN05040.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_24 PF13578.6 GAN05040.1 - 0.0016 19.4 0.1 0.0059 17.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAN05040.1 - 0.0019 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 GAN05040.1 - 0.0046 16.6 0.1 0.0074 15.9 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 GAN05040.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase CPSF73-100_C PF11718.8 GAN05040.1 - 0.019 14.5 1.1 0.039 13.5 1.1 1.5 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term CheR PF01739.18 GAN05040.1 - 0.071 12.6 0.0 2.4 7.6 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain RasGAP PF00616.19 GAN05041.1 - 9.1e-26 90.9 0.1 8.2e-18 64.9 0.0 3.0 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAN05041.1 - 7e-19 68.4 0.2 2.7e-18 66.5 0.2 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAN05041.1 - 2.4e-08 33.8 0.1 6.7e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT PF02985.22 GAN05041.1 - 0.00028 20.9 1.1 0.01 16.0 0.2 3.9 2 0 0 2 2 2 1 HEAT repeat Cnd1 PF12717.7 GAN05041.1 - 0.00071 19.7 0.0 0.016 15.2 0.0 3.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.6 GAN05041.1 - 0.0069 16.3 0.0 0.052 13.4 0.0 2.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Peptidase_M13_N PF05649.13 GAN05042.1 - 5.4e-79 266.6 0.0 6.8e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAN05042.1 - 2e-67 226.7 0.3 3.6e-67 225.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.18 GAN05042.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 Thioredoxin PF00085.20 GAN05043.1 - 1.1e-20 73.5 0.0 1.4e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAN05043.1 - 0.00094 19.6 0.0 0.0023 18.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAN05043.1 - 0.0071 16.5 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 GAN05043.1 - 0.031 13.6 0.0 0.049 13.0 0.0 1.3 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAN05043.1 - 0.058 13.7 0.0 0.19 12.1 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin-like 2Fe-2S_thioredx PF01257.19 GAN05043.1 - 0.11 12.3 0.0 12 5.8 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin TrbC_Ftype PF09673.10 GAN05043.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TPR_2 PF07719.17 GAN05044.1 - 9.1e-52 169.1 37.7 0.00011 22.0 0.1 17.3 18 0 0 18 18 16 10 Tetratricopeptide repeat TPR_1 PF00515.28 GAN05044.1 - 1.7e-45 151.0 37.3 2.9e-06 26.9 0.2 15.8 17 0 0 17 17 16 8 Tetratricopeptide repeat TPR_8 PF13181.6 GAN05044.1 - 6.9e-36 119.5 33.7 3.2e-08 33.2 0.1 15.1 16 0 0 16 16 15 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAN05044.1 - 8.2e-30 102.9 30.2 2.4e-07 30.9 0.1 13.7 13 1 1 14 14 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAN05044.1 - 3.4e-29 99.0 15.0 0.016 16.0 0.2 15.4 11 3 5 16 16 14 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAN05044.1 - 2.1e-25 87.2 29.4 0.017 15.4 0.0 17.1 18 0 0 18 18 17 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAN05044.1 - 7.7e-24 84.1 10.5 4.8e-05 23.9 0.1 9.9 9 2 4 13 13 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAN05044.1 - 4.7e-23 81.5 28.8 1.1e-05 25.9 0.2 11.9 11 3 3 14 14 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAN05044.1 - 8.4e-15 54.2 29.0 0.037 13.7 0.0 12.3 13 2 1 14 14 13 5 TPR repeat TPR_7 PF13176.6 GAN05044.1 - 2.8e-14 52.0 22.3 0.16 12.0 0.0 11.1 14 0 0 14 14 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 GAN05044.1 - 5.8e-13 48.8 6.4 0.15 12.2 0.0 8.9 8 3 3 12 12 12 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAN05044.1 - 6.4e-10 38.6 20.0 0.24 11.3 0.1 11.4 14 0 0 14 14 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAN05044.1 - 9.8e-09 35.3 25.3 0.24 12.1 0.1 13.2 14 1 0 14 14 11 1 Tetratricopeptide repeat DUF3808 PF10300.9 GAN05044.1 - 4.9e-05 22.3 4.2 0.013 14.3 0.8 2.8 2 1 0 3 3 3 2 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 GAN05044.1 - 0.0001 22.5 25.8 0.00085 19.5 0.5 7.9 7 1 3 10 10 9 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 GAN05044.1 - 0.00096 18.3 8.1 1.6 7.6 0.1 5.4 4 1 1 5 5 5 1 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 GAN05044.1 - 0.0041 17.3 0.6 6.6 7.2 0.0 4.8 4 0 0 4 4 3 1 PPR repeat TPR_20 PF14561.6 GAN05044.1 - 0.01 16.2 3.4 25 5.3 0.0 5.5 5 1 0 5 5 4 0 Tetratricopeptide repeat FAT PF02259.23 GAN05044.1 - 0.016 14.4 10.2 0.12 11.6 0.7 5.1 3 1 0 4 4 4 0 FAT domain DUF3856 PF12968.7 GAN05044.1 - 0.092 12.8 4.6 17 5.4 0.0 5.5 5 0 0 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_22 PF18833.1 GAN05044.1 - 0.12 12.6 4.0 0.2 11.8 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat fn3_3 PF14686.6 GAN05044.1 - 0.15 11.8 0.2 0.37 10.6 0.2 1.6 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II DUF2225 PF09986.9 GAN05044.1 - 0.17 11.6 10.3 6.4 6.4 0.1 5.4 6 1 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 GAN05044.1 - 0.19 12.4 8.4 11 7.0 0.4 6.1 7 0 0 7 7 4 0 Tetratricopeptide repeat Aldolase_II PF00596.21 GAN05045.1 - 6.8e-47 159.8 0.1 1e-46 159.3 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MotA_activ PF09114.10 GAN05045.1 - 0.15 12.2 0.0 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcription factor MotA, activation domain G-patch PF01585.23 GAN05045.1 - 0.2 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 G-patch domain Paf67 PF10255.9 GAN05046.1 - 1.1e-168 561.5 6.9 1.4e-168 561.1 6.9 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 GAN05046.1 - 0.00016 21.5 0.0 0.00099 19.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAN05046.1 - 0.0008 19.1 0.0 0.0044 16.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN05046.1 - 0.014 15.6 0.0 0.36 11.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran PF00005.27 GAN05047.1 - 2.2e-46 157.8 0.7 4e-22 79.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAN05047.1 - 2.9e-24 84.9 4.8 2.9e-24 84.9 4.8 3.3 3 0 0 3 3 1 1 ABC transporter SMC_N PF02463.19 GAN05047.1 - 6.9e-12 45.3 4.0 0.0016 17.9 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAN05047.1 - 6.5e-11 42.6 10.7 0.025 14.4 0.1 4.9 3 2 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAN05047.1 - 1.5e-08 35.2 0.6 0.0041 17.5 0.1 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAN05047.1 - 4.7e-08 33.4 0.8 0.021 15.1 0.1 4.4 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.6 GAN05047.1 - 7.7e-07 28.8 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAN05047.1 - 1.1e-06 28.6 0.0 0.085 12.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAN05047.1 - 2.7e-06 27.7 0.5 0.11 12.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 GAN05047.1 - 5.4e-06 27.0 2.1 0.039 14.5 0.0 4.4 4 2 1 5 5 5 2 AAA domain AAA_23 PF13476.6 GAN05047.1 - 6.1e-06 26.9 27.8 0.11 13.0 0.0 5.2 5 0 0 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 GAN05047.1 - 1.2e-05 25.3 0.0 0.069 13.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 GAN05047.1 - 0.00013 21.8 0.1 0.68 9.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAN05047.1 - 0.00023 21.0 0.0 0.017 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAN05047.1 - 0.00031 20.9 2.6 0.42 10.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 GAN05047.1 - 0.0019 18.2 0.0 1.6 8.6 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_27 PF13514.6 GAN05047.1 - 0.0043 16.7 4.8 0.22 11.1 0.0 3.1 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 GAN05047.1 - 0.0045 17.3 0.0 2.4 8.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 GAN05047.1 - 0.005 16.9 3.4 1.6 8.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 GAN05047.1 - 0.0078 16.6 0.7 5.8 7.4 0.0 3.8 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 GAN05047.1 - 0.022 13.7 0.0 4.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 GAN05047.1 - 0.03 13.6 0.0 10 5.3 0.0 2.6 2 0 0 2 2 2 0 Septin Roc PF08477.13 GAN05047.1 - 0.032 14.5 0.0 9 6.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAN05047.1 - 0.039 14.0 11.9 0.39 10.8 0.0 3.8 4 1 0 4 4 4 0 Dynamin family dNK PF01712.19 GAN05047.1 - 0.039 13.8 1.2 2.1 8.1 0.0 3.4 3 0 0 3 3 3 0 Deoxynucleoside kinase Ploopntkinase1 PF18748.1 GAN05047.1 - 0.062 12.8 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 cobW PF02492.19 GAN05047.1 - 0.063 12.9 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAN05047.1 - 0.073 12.2 0.0 7 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 GAN05047.1 - 0.092 12.3 0.0 4.4 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAN05047.1 - 0.093 12.6 0.0 7.5 6.4 0.0 2.7 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 GAN05047.1 - 0.11 12.3 3.1 4.6 7.0 0.0 3.4 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 GAN05047.1 - 0.13 11.8 0.3 8.5 5.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 GAN05047.1 - 0.15 12.2 0.0 0.15 12.2 0.0 4.5 3 1 2 5 5 5 0 Helicase HerA, central domain AAA_15 PF13175.6 GAN05047.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.7 4 2 1 5 5 5 0 AAA ATPase domain UPF0184 PF03670.13 GAN05047.1 - 0.26 11.7 5.0 3.6 8.0 2.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Cytidylate_kin PF02224.18 GAN05047.1 - 1.6 8.4 0.0 1.6 8.4 0.0 3.1 4 0 0 4 4 4 0 Cytidylate kinase Med4 PF10018.9 GAN05047.1 - 2.3 7.9 10.6 0.021 14.5 1.9 1.9 2 0 0 2 2 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF5320 PF17253.2 GAN05047.1 - 5.6 8.1 6.3 21 6.3 1.8 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) NMT1 PF09084.11 GAN05048.1 - 8.1e-69 231.8 0.0 1.1e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 GAN05048.1 - 0.00029 20.5 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 GAN05048.1 - 0.073 12.2 0.0 0.39 9.8 0.0 1.9 2 0 0 2 2 2 0 PBP superfamily domain NMT1_2 PF13379.6 GAN05048.1 - 0.088 12.5 0.1 0.58 9.8 0.0 2.2 3 0 0 3 3 3 0 NMT1-like family Blo-t-5 PF11642.8 GAN05049.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Mite allergen Blo t 5 Ycf70 PF17382.2 GAN05049.1 - 5.4 7.5 5.8 4.4 7.8 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized Ycf70-like ETC_C1_NDUFA5 PF04716.14 GAN05050.1 - 1.3e-28 98.6 1.2 1.3e-28 98.6 1.2 1.7 2 0 0 2 2 2 1 ETC complex I subunit conserved region EF-hand_7 PF13499.6 GAN05051.1 - 6e-08 33.0 2.2 1.6e-07 31.7 2.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAN05051.1 - 8e-08 31.6 0.8 1.4e-05 24.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAN05051.1 - 2e-05 23.8 2.7 0.019 14.5 0.1 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 GAN05051.1 - 0.002 18.4 0.2 0.0045 17.3 0.2 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 GAN05051.1 - 0.15 11.6 0.7 6.5 6.4 0.1 2.5 2 0 0 2 2 2 0 EF hand Topoisom_bac PF01131.20 GAN05052.1 - 2.5e-102 343.0 0.0 3.3e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 GAN05052.1 - 3.2e-13 49.8 0.0 5.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain MFS_1 PF07690.16 GAN05054.1 - 6.1e-38 130.6 23.6 6.1e-38 130.6 23.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 GAN05054.1 - 8.9 6.6 13.4 22 5.4 5.9 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 GAN05055.1 - 6.7e-35 120.6 32.4 6.7e-35 120.6 32.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 GAN05055.1 - 1.4 9.3 11.1 16 5.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4625 PF15418.6 GAN05056.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) PAP1 PF08601.10 GAN05057.1 - 2.3 7.9 14.4 2.4 7.8 14.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Ribosomal_L7Ae PF01248.26 GAN05058.1 - 6.9e-26 89.8 0.0 8.3e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 GAN05058.1 - 0.00069 19.5 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 GAN05058.1 - 0.0037 17.3 0.0 0.0039 17.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 ALMT PF11744.8 GAN05059.1 - 2.7e-20 72.7 6.3 2.7e-20 72.7 6.3 2.1 1 1 1 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.6 GAN05059.1 - 1.8e-10 41.0 11.1 3.1e-10 40.3 10.9 1.5 1 1 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAN05059.1 - 4.1e-08 32.2 7.6 7.6e-08 31.4 7.6 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 GAN05059.1 - 1.3 8.0 10.1 0.89 8.5 1.0 2.5 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal Rhodanese PF00581.20 GAN05060.1 - 2.9e-23 82.4 0.0 7.8e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.6 GAN05060.1 - 0.11 12.3 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 ThiC-associated domain Reo_sigmaC PF04582.12 GAN05060.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain Fibrillarin PF01269.17 GAN05061.1 - 4.5e-108 359.6 0.1 5.7e-108 359.3 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 GAN05061.1 - 4.4e-05 23.3 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 GAN05061.1 - 0.02 15.0 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 GAN05061.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 GAN05061.1 - 0.029 14.0 0.0 0.074 12.7 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF1977 PF09320.11 GAN05062.1 - 1.9e-28 98.8 0.5 4.3e-28 97.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 GAN05062.1 - 3e-23 81.7 0.6 5.8e-23 80.8 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Gpi1 PF05024.15 GAN05062.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) TPR_2 PF07719.17 GAN05062.1 - 0.069 13.3 1.0 0.41 10.9 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Dmrt1 PF12374.8 GAN05062.1 - 0.2 12.1 6.8 0.53 10.8 6.8 1.6 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 PepSY_2 PF13670.6 GAN05062.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.0 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain BTB_2 PF02214.22 GAN05063.1 - 0.063 13.6 1.2 1.1 9.7 0.2 3.0 1 1 2 3 3 3 0 BTB/POZ domain Ribosomal_S6e PF01092.19 GAN05064.1 - 3e-08 33.7 1.2 4.9e-08 33.0 1.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S6e Pyrophosphatase PF00719.19 GAN05065.1 - 7.3e-57 191.6 0.9 7.3e-57 191.6 0.9 1.4 2 0 0 2 2 2 1 Inorganic pyrophosphatase SH3_2 PF07653.17 GAN05066.1 - 1.2e-06 28.1 0.0 5.5e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 GAN05066.1 - 5.3e-06 25.9 0.0 9.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN05066.1 - 2.4e-05 24.1 0.1 3.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain ARD PF03079.14 GAN05066.1 - 0.036 14.3 1.3 0.036 14.3 1.3 1.6 2 0 0 2 2 2 0 ARD/ARD' family DUF1635 PF07795.11 GAN05066.1 - 0.085 12.7 3.6 0.15 11.9 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) zf-RVT PF13966.6 GAN05067.1 - 1.2e-05 26.0 1.5 1.5e-05 25.6 1.5 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Homeodomain PF00046.29 GAN05068.1 - 1.4e-15 56.9 0.9 2.5e-15 56.1 0.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN05068.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.6 GAN05068.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HSP70 PF00012.20 GAN05069.1 - 4.5e-221 735.2 13.6 1.2e-220 733.8 13.6 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN05069.1 - 6.1e-13 48.3 1.4 8.1e-12 44.6 0.7 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAN05069.1 - 0.0035 17.1 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Asp_decarbox PF02261.16 GAN05069.1 - 0.036 14.0 0.0 0.094 12.7 0.0 1.7 1 0 0 1 1 1 0 Aspartate decarboxylase eIF3_N PF09440.10 GAN05069.1 - 0.22 12.0 5.4 0.16 12.4 1.9 2.4 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain NDK PF00334.19 GAN05070.1 - 1.4e-51 174.0 0.0 2.1e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CAP_GLY PF01302.25 GAN05071.1 - 1.1e-22 79.8 0.2 1.8e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 GAN05071.1 - 5.3e-06 26.2 18.3 0.0012 18.7 1.9 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle Prismane PF03063.20 GAN05071.1 - 1.2 7.8 8.2 0.83 8.3 6.2 1.5 1 1 0 1 1 1 0 Prismane/CO dehydrogenase family GP41 PF00517.17 GAN05071.1 - 8.5 6.2 14.0 3.7 7.4 0.1 3.1 3 1 0 3 3 3 0 Retroviral envelope protein Peptidase_C65 PF10275.9 GAN05073.1 - 6.2e-69 232.2 0.5 7.5e-69 231.9 0.5 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 GAN05073.1 - 2.3e-08 34.6 0.3 3.2e-07 30.9 0.1 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease PUB PF09409.10 GAN05073.1 - 0.03 14.3 0.1 0.077 12.9 0.1 1.8 1 1 0 1 1 1 0 PUB domain Ran_BP1 PF00638.18 GAN05074.1 - 8.2e-51 171.4 3.6 1.2e-50 170.9 3.6 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 GAN05074.1 - 0.00012 21.9 1.3 0.0013 18.6 1.3 2.1 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 GAN05074.1 - 0.042 13.6 1.1 0.051 13.3 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) WD40 PF00400.32 GAN05076.1 - 7.9e-13 48.7 0.2 8.2e-06 26.5 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05076.1 - 6.6e-09 36.0 0.0 0.01 16.1 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAN05076.1 - 0.029 14.3 0.0 8.9 6.4 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MBOAT_2 PF13813.6 GAN05077.1 - 9.6e-15 54.6 1.9 9.6e-15 54.6 1.9 2.3 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family MSP1a PF11670.8 GAN05077.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) LEA_2 PF03168.13 GAN05078.1 - 0.00026 21.5 0.0 0.00042 20.8 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein ECSCR PF15820.5 GAN05078.1 - 0.024 14.4 0.9 0.7 9.8 0.5 2.4 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator WBP-1 PF11669.8 GAN05078.1 - 0.52 11.0 6.4 1.6 9.4 5.4 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 UPF0052 PF01933.18 GAN05079.1 - 5e-52 176.9 0.0 6.5e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 UPF0524 PF15823.5 GAN05079.1 - 0.0096 15.3 0.8 3.2 7.1 0.2 2.3 2 0 0 2 2 2 2 UPF0524 of C3orf70 UTP25 PF06862.12 GAN05080.1 - 3.4e-194 646.0 9.3 5.4e-194 645.3 9.3 1.3 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 p450 PF00067.22 GAN05081.1 - 7.5e-94 315.1 0.0 1.1e-93 314.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 GAN05081.1 - 3.2e-34 118.4 0.0 8.5e-33 113.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN05081.1 - 4.9e-26 91.7 0.5 1.1e-25 90.5 0.5 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAN05081.1 - 1.2e-18 67.7 0.0 2.8e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAN05081.1 - 7.5e-05 22.9 0.0 0.011 15.9 0.0 2.6 1 1 0 2 2 2 1 Ferric reductase NAD binding domain RhoGEF PF00621.20 GAN05082.1 - 1.3e-34 120.0 4.1 1.3e-34 120.0 4.1 1.7 2 0 0 2 2 2 1 RhoGEF domain Arrestin_C PF02752.22 GAN05083.1 - 6.3e-14 52.6 5.5 3.9e-09 37.1 1.0 3.4 2 2 1 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN05083.1 - 0.0069 16.4 0.0 1.5 8.9 0.0 3.0 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain TIG PF01833.24 GAN05084.1 - 2.6e-13 49.8 0.5 1.1e-12 47.8 0.5 2.2 1 0 0 1 1 1 1 IPT/TIG domain HD_assoc PF13286.6 GAN05084.1 - 0.0025 18.3 0.5 0.0025 18.3 0.5 3.1 3 0 0 3 3 3 1 Phosphohydrolase-associated domain SUIM_assoc PF16619.5 GAN05084.1 - 0.011 15.8 0.3 0.011 15.8 0.3 6.0 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ESM4 PF15952.5 GAN05084.1 - 5.1 7.5 38.4 3.5 8.0 4.5 3.4 3 0 0 3 3 3 0 Enhancer of split M4 family PGAP1 PF07819.13 GAN05085.1 - 1.5e-05 24.8 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 GAN05085.1 - 5.9e-05 23.0 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 GAN05085.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 GAN05085.1 - 0.00019 21.2 0.2 0.0011 18.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN05085.1 - 0.00082 20.0 0.0 0.001 19.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 GAN05085.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 GAN05085.1 - 0.019 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Sec34 PF04136.15 GAN05086.1 - 0.011 15.7 5.0 0.011 15.7 5.0 2.1 2 0 0 2 2 2 0 Sec34-like family FlaC_arch PF05377.11 GAN05086.1 - 0.029 14.8 14.8 0.28 11.6 5.6 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) T3SSipB PF16535.5 GAN05086.1 - 0.037 14.5 13.8 0.19 12.2 13.4 1.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB SKA1 PF07160.12 GAN05086.1 - 0.038 13.8 10.2 0.05 13.4 10.2 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CCDC-167 PF15188.6 GAN05086.1 - 0.04 14.3 17.2 0.046 14.1 9.4 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4226 PF10774.9 GAN05086.1 - 0.047 14.0 4.1 0.086 13.1 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) NPV_P10 PF05531.12 GAN05086.1 - 0.1 13.1 10.7 2.4 8.7 10.3 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Noelin-1 PF12308.8 GAN05086.1 - 0.1 12.6 6.6 1.2 9.2 0.4 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein Prefoldin_3 PF13758.6 GAN05086.1 - 0.11 12.5 7.4 0.045 13.8 4.3 1.9 1 1 2 3 3 3 0 Prefoldin subunit DUF2381 PF09544.10 GAN05086.1 - 0.11 12.0 3.6 0.091 12.3 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2381) DUF1664 PF07889.12 GAN05086.1 - 0.17 11.9 12.3 0.07 13.2 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 GAN05086.1 - 0.19 11.7 13.1 0.3 11.1 8.3 2.5 1 1 1 2 2 2 0 Laminin Domain II SAS4 PF15460.6 GAN05086.1 - 0.28 11.3 13.9 0.47 10.6 12.5 1.8 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 ERM PF00769.19 GAN05086.1 - 0.42 10.4 19.6 0.71 9.6 19.6 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 GAN05086.1 - 0.46 10.6 23.2 0.13 12.3 14.5 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain MtrG PF04210.13 GAN05086.1 - 0.48 10.3 4.5 14 5.6 0.1 3.4 1 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Phage_GP20 PF06810.11 GAN05086.1 - 0.51 10.1 22.7 1.6 8.5 22.7 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 Flu_NS2 PF00601.19 GAN05086.1 - 0.58 10.5 5.6 1 9.7 0.9 2.3 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) bZIP_Maf PF03131.17 GAN05086.1 - 0.59 10.7 14.2 1.1 9.8 6.6 3.1 2 1 1 3 3 3 0 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.9 GAN05086.1 - 0.65 10.2 18.3 0.57 10.4 16.9 1.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 GAN05086.1 - 0.66 10.5 26.5 4.1 7.9 0.1 3.2 2 1 1 3 3 3 0 Cell division protein ZapB Takusan PF04822.13 GAN05086.1 - 0.88 9.5 11.0 0.12 12.3 6.3 1.9 2 0 0 2 2 2 0 Takusan Nup54 PF13874.6 GAN05086.1 - 0.98 9.5 9.9 0.11 12.6 0.8 2.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 dCache_2 PF08269.11 GAN05086.1 - 1 8.5 7.5 1.6 7.9 7.5 1.3 1 0 0 1 1 1 0 Cache domain NBP1 PF08537.10 GAN05086.1 - 1 8.7 17.7 2.4 7.5 13.9 1.9 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 ISG65-75 PF11727.8 GAN05086.1 - 1.1 8.4 12.9 0.63 9.2 6.9 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein DivIC PF04977.15 GAN05086.1 - 1.1 9.0 23.5 9 6.1 9.6 3.1 2 1 1 3 3 3 0 Septum formation initiator DASH_Dam1 PF08653.10 GAN05086.1 - 1.2 9.0 4.4 3.5 7.5 0.0 3.1 3 1 1 4 4 4 0 DASH complex subunit Dam1 TMF_TATA_bd PF12325.8 GAN05086.1 - 1.2 9.3 20.7 0.3 11.3 12.0 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 GAN05086.1 - 1.4 7.4 3.1 1.5 7.2 3.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 GAN05086.1 - 1.4 9.7 8.3 0.62 10.8 4.9 1.9 2 0 0 2 2 2 0 Occludin homology domain DivIVA PF05103.13 GAN05086.1 - 1.6 8.8 17.2 7.9 6.6 0.4 2.7 1 1 1 2 2 2 0 DivIVA protein Spc7 PF08317.11 GAN05086.1 - 2 7.2 22.4 1.9 7.3 11.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 GAN05086.1 - 2.1 8.7 13.8 5.9 7.2 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein Rx_N PF18052.1 GAN05086.1 - 2.8 8.3 15.4 0.63 10.3 2.1 3.0 1 1 2 3 3 3 0 Rx N-terminal domain APG6_N PF17675.1 GAN05086.1 - 3.2 8.3 26.6 1.1 9.7 17.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 GAN05086.1 - 3.7 6.7 11.7 1.6 7.9 6.8 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 GAN05086.1 - 4.2 8.1 11.9 2.7e+02 2.3 11.9 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) VPS11_C PF12451.8 GAN05086.1 - 4.3 7.6 5.9 4.6 7.6 2.9 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal UPF0242 PF06785.11 GAN05086.1 - 4.8 7.2 20.7 4.7 7.3 12.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LUC7 PF03194.15 GAN05086.1 - 5 6.7 12.5 11 5.6 12.5 1.7 1 1 0 1 1 1 0 LUC7 N_terminus DUF5339 PF17274.2 GAN05086.1 - 5 8.1 13.4 16 6.5 4.3 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5339) V_ATPase_I PF01496.19 GAN05086.1 - 5.3 4.8 9.8 6.4 4.6 9.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 GAN05086.1 - 5.6 5.4 15.9 0.45 9.1 9.7 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4279 PF14106.6 GAN05086.1 - 6.3 7.0 7.7 2 8.6 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) Atg14 PF10186.9 GAN05086.1 - 7.3 5.6 16.5 12 4.9 11.7 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 GAN05086.1 - 7.8 5.3 6.4 7.9 5.3 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 GAN05086.1 - 8 6.2 14.5 0.62 9.9 7.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 GAN05086.1 - 8.6 5.6 14.4 28 3.9 14.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COPI_assoc PF08507.10 GAN05087.1 - 8.2e-21 74.4 11.8 1.1e-20 74.0 11.8 1.1 1 0 0 1 1 1 1 COPI associated protein PQ-loop PF04193.14 GAN05087.1 - 0.065 13.0 2.3 6.8 6.5 0.1 2.9 2 1 0 2 2 2 0 PQ loop repeat DUF4386 PF14329.6 GAN05087.1 - 0.67 9.8 12.4 0.061 13.2 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4386) AtpR PF12966.7 GAN05087.1 - 2 8.9 10.2 0.74 10.3 0.6 2.7 2 1 1 3 3 3 0 N-ATPase, AtpR subunit DUF2678 PF10856.8 GAN05087.1 - 8.4 6.4 12.0 0.59 10.1 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) TCR_zetazeta PF11628.8 GAN05087.1 - 8.6 6.1 7.8 1.1 9.0 0.3 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain PEX11 PF05648.14 GAN05088.1 - 4.4e-14 52.5 0.9 6.4e-14 52.0 0.9 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) EMP70 PF02990.16 GAN05089.1 - 3.8e-146 487.8 12.3 4.6e-146 487.5 12.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF21 PF01595.20 GAN05089.1 - 0.12 12.0 2.8 0.69 9.6 0.3 2.8 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain ASFV_J13L PF05568.11 GAN05089.1 - 1.1 9.0 2.4 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 African swine fever virus J13L protein MARVEL PF01284.23 GAN05090.1 - 1.9e-08 34.4 8.8 3.3e-08 33.7 8.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Phage_Gp23 PF10669.9 GAN05090.1 - 0.0098 16.2 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) 2TM PF13239.6 GAN05090.1 - 1.4 9.2 4.8 6.6 7.1 4.8 2.1 1 1 0 1 1 1 0 2TM domain Lung_7-TM_R PF06814.13 GAN05091.1 - 1.3e-34 119.8 17.3 2.9e-34 118.7 17.3 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor SecD-TM1 PF13721.6 GAN05091.1 - 3.7 8.0 4.7 28 5.2 0.0 2.9 3 0 0 3 3 3 0 SecD export protein N-terminal TM region Glyco_transf_34 PF05637.12 GAN05092.1 - 2.5e-20 73.2 1.0 9e-20 71.4 1.0 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GAN05092.1 - 2.7e-08 33.7 0.0 6.2e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 GAN05092.1 - 0.044 13.7 0.1 0.094 12.7 0.1 1.6 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Pneumo_att_G PF05539.11 GAN05092.1 - 3.5 7.1 5.3 5.2 6.6 5.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DHDPS PF00701.22 GAN05093.1 - 2.5e-48 164.3 0.0 3.1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3449 PF11931.8 GAN05096.1 - 1.3e-77 259.8 5.6 5e-77 257.9 2.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 GAN05096.1 - 2.5e-25 88.8 5.4 2.5e-25 88.8 5.4 2.7 3 1 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 GAN05096.1 - 2.5e-12 46.4 0.2 6.7e-12 45.1 0.2 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 GAN05096.1 - 7.6e-09 35.7 2.1 8.1e-06 26.1 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN05096.1 - 3.7e-06 27.1 0.8 3.7e-06 27.1 0.8 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAN05096.1 - 0.00031 21.0 7.1 0.0011 19.3 1.4 3.7 3 1 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN05096.1 - 0.0089 16.8 1.4 5.7 8.0 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Hormone_3 PF00159.18 GAN05096.1 - 0.016 15.3 0.2 0.077 13.1 0.2 2.2 1 0 0 1 1 1 0 Pancreatic hormone peptide Mak10 PF04112.13 GAN05097.1 - 5.5e-48 162.6 0.5 1.2e-47 161.6 0.5 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Herpes_Helicase PF02689.14 GAN05098.1 - 1e-07 30.4 0.0 1e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Helicase PHD PF00628.29 GAN05099.1 - 5.6e-07 29.4 6.9 1.3e-06 28.2 6.9 1.7 1 0 0 1 1 1 1 PHD-finger TORC_C PF12886.7 GAN05099.1 - 0.075 13.6 1.4 6.6 7.3 0.0 3.7 3 0 0 3 3 3 0 Transducer of regulated CREB activity, C terminus Colicin-DNase PF12639.7 GAN05099.1 - 1.3 9.9 4.5 2 9.3 0.9 2.7 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin PHD_4 PF16866.5 GAN05099.1 - 7.9 6.6 11.8 0.56 10.3 6.2 2.0 2 0 0 2 2 2 0 PHD-finger PEX11 PF05648.14 GAN05100.1 - 1.1e-26 93.7 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PPR_2 PF13041.6 GAN05101.1 - 9.9e-42 140.9 8.9 2e-11 43.9 0.0 9.2 9 1 1 10 10 10 5 PPR repeat family PPR_3 PF13812.6 GAN05101.1 - 8e-32 109.1 2.1 3.6e-10 39.8 0.0 7.1 5 2 2 7 7 7 4 Pentatricopeptide repeat domain PP2C PF00481.21 GAN05101.1 - 1.1e-19 71.1 0.0 8.4e-19 68.2 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C PPR_1 PF12854.7 GAN05101.1 - 3.1e-19 68.3 0.2 1.6e-06 27.7 0.0 7.5 9 0 0 9 9 9 3 PPR repeat PPR PF01535.20 GAN05101.1 - 9e-19 66.3 5.9 6.4e-06 26.1 0.0 9.5 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 GAN05101.1 - 1.1e-13 51.0 8.7 0.0011 18.4 0.0 5.2 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP PP2C_2 PF13672.6 GAN05101.1 - 0.0029 17.3 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C AdoMet_MTase PF07757.13 GAN05101.1 - 0.16 12.3 0.1 0.93 9.9 0.0 2.3 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase TPR_19 PF14559.6 GAN05101.1 - 0.49 10.9 4.9 20 5.8 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 GAN05102.1 - 3.2e-32 111.6 0.0 7.1e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chalcone_3 PF16036.5 GAN05102.1 - 1.7 8.7 6.2 0.7 10.0 1.1 2.4 2 0 0 2 2 2 0 Chalcone isomerase-like Rhomboid PF01694.22 GAN05103.1 - 0.02 14.9 7.0 0.046 13.7 7.0 1.5 1 0 0 1 1 1 0 Rhomboid family Roughex PF06020.11 GAN05103.1 - 1.7 7.7 12.3 2.7 7.0 12.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF2407 PF10302.9 GAN05103.1 - 4.8 7.8 5.6 13 6.4 5.6 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Peptidase_C14 PF00656.22 GAN05104.1 - 2e-40 139.3 0.1 3.7e-40 138.4 0.1 1.4 1 0 0 1 1 1 1 Caspase domain Fungal_trans PF04082.18 GAN05105.1 - 1.7e-24 86.3 0.0 6.1e-24 84.5 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain RasGAP PF00616.19 GAN05105.1 - 0.019 14.7 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase RAP1 PF07218.11 GAN05105.1 - 0.17 10.1 0.0 0.36 9.0 0.0 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF842 PF05811.13 GAN05105.1 - 0.2 11.4 0.2 0.85 9.3 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) ADH_N_2 PF16884.5 GAN05106.1 - 1.8e-22 79.3 0.0 3.3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAN05106.1 - 6.6e-22 77.9 0.0 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN05106.1 - 0.0026 18.8 0.0 0.0045 18.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Phytochelatin PF05023.14 GAN05107.1 - 2e-84 282.1 0.0 3e-84 281.5 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 GAN05107.1 - 0.015 15.8 0.0 0.09 13.3 0.0 2.3 1 1 0 1 1 1 0 Peptidase_C39 like family Longin PF13774.6 GAN05108.1 - 8e-14 51.4 0.0 1.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAN05108.1 - 4.6e-11 42.4 1.7 1.3e-10 40.9 1.7 1.7 1 1 0 1 1 1 1 Synaptobrevin PBP1_TM PF14812.6 GAN05109.1 - 0.062 13.7 0.5 0.11 12.9 0.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CPSase_L_D2 PF02786.17 GAN05110.1 - 1.1e-106 355.0 0.0 1.2e-82 276.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 GAN05110.1 - 1.2e-34 119.3 0.0 3.1e-34 117.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 GAN05110.1 - 4e-14 52.5 0.0 3e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAN05110.1 - 1.9e-12 47.2 0.1 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAN05110.1 - 2.3e-10 40.3 0.0 8.3e-05 22.3 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 GAN05110.1 - 6.8e-06 25.7 0.0 0.00099 18.6 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 GAN05110.1 - 0.00011 21.9 0.0 0.24 11.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain TrkA_N PF02254.18 GAN05110.1 - 0.0072 16.6 0.0 0.15 12.3 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain MGS PF02142.22 GAN05110.1 - 0.13 12.5 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 MGS-like domain DUF1752 PF08550.10 GAN05112.1 - 3.5e-14 52.3 0.8 8e-14 51.2 0.8 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) WWE PF02825.20 GAN05113.1 - 0.0063 17.1 0.2 0.0068 17.0 0.2 1.1 1 0 0 1 1 1 1 WWE domain CTP_transf_1 PF01148.20 GAN05114.1 - 1.7e-75 254.2 25.5 2.2e-75 253.9 25.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF4389 PF14333.6 GAN05114.1 - 2.9 7.9 21.6 2.2 8.2 2.3 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4389) Peptidase_S8 PF00082.22 GAN05115.1 - 5.6e-80 268.8 0.1 1.9e-79 267.0 0.0 1.8 2 0 0 2 2 2 1 Subtilase family TPPII PF12580.8 GAN05115.1 - 8.3e-54 182.0 0.5 1.3e-53 181.3 0.5 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Rhomboid_N PF12122.8 GAN05115.1 - 0.1 12.8 0.6 6.9 6.9 0.2 2.8 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease CREPT PF16566.5 GAN05115.1 - 1.5 9.0 14.2 4.4 7.5 0.0 3.7 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2046 PF09755.9 GAN05116.1 - 7.6e-31 107.5 48.9 3.7e-30 105.2 32.0 3.0 1 1 2 3 3 3 2 Uncharacterized conserved protein H4 (DUF2046) Z1 PF10593.9 GAN05116.1 - 9.8 5.6 17.4 7.7 5.9 3.0 2.2 2 0 0 2 2 2 0 Z1 domain adh_short_C2 PF13561.6 GAN05117.1 - 1.9e-67 227.3 1.7 2.3e-67 227.0 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN05117.1 - 5.7e-55 185.8 3.1 7.6e-55 185.4 3.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN05117.1 - 2.2e-14 53.8 0.7 3.3e-14 53.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN05117.1 - 4.5e-08 32.8 0.2 6.3e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN05117.1 - 5.3e-07 28.9 0.3 7.2e-07 28.5 0.3 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 GAN05117.1 - 0.0032 16.9 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Methyltransf_25 PF13649.6 GAN05117.1 - 0.024 15.4 0.5 0.085 13.6 0.3 2.0 2 1 0 2 2 2 0 Methyltransferase domain RmlD_sub_bind PF04321.17 GAN05117.1 - 0.063 12.4 1.9 0.079 12.0 1.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain MgsA_C PF12002.8 GAN05117.1 - 0.078 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Ribosomal_S11 PF00411.19 GAN05117.1 - 0.13 12.6 0.5 19 5.7 0.0 2.6 1 1 0 2 2 2 0 Ribosomal protein S11 ApoLp-III PF07464.11 GAN05117.1 - 0.14 12.2 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) polyprenyl_synt PF00348.17 GAN05118.1 - 1.8e-65 220.5 0.0 2.1e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MCPVI PF02993.14 GAN05119.1 - 0.021 14.7 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Cep57_CLD PF14073.6 GAN05119.1 - 0.044 13.8 2.2 0.06 13.4 2.2 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 EF-hand_9 PF14658.6 GAN05119.1 - 0.11 12.9 0.7 17 5.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Ly49 PF08391.10 GAN05119.1 - 0.25 11.7 1.9 0.42 11.0 1.9 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region ALG11_N PF15924.5 GAN05120.1 - 3.7e-91 304.8 1.4 5.6e-91 304.2 1.4 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 GAN05120.1 - 9.3e-23 80.6 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN05120.1 - 5.4e-09 36.6 0.0 9.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAN05120.1 - 0.00073 19.9 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN05120.1 - 0.071 13.1 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase Family 4 U3_snoRNA_assoc PF08297.11 GAN05121.1 - 0.00014 22.5 7.1 0.00014 22.5 7.1 3.5 2 1 1 3 3 3 1 U3 snoRNA associated Caldesmon PF02029.15 GAN05121.1 - 0.25 10.0 42.5 0.31 9.7 42.5 1.0 1 0 0 1 1 1 0 Caldesmon Aldo_ket_red PF00248.21 GAN05122.1 - 2.3e-42 145.2 0.0 2.9e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF325 PF03804.13 GAN05122.1 - 0.15 12.1 0.4 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 Viral proteins of unknown function Exotox-A_cataly PF09009.10 GAN05122.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic HNH PF01844.23 GAN05125.1 - 0.02 15.1 1.9 0.02 15.1 1.9 2.5 2 1 0 2 2 2 0 HNH endonuclease PRP1_N PF06424.12 GAN05126.1 - 1.6e-51 174.6 4.7 3.2e-51 173.6 4.7 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 GAN05126.1 - 3.5e-37 123.9 16.6 0.00048 20.7 0.0 14.8 4 3 11 15 15 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 GAN05126.1 - 7.6e-27 93.6 6.1 9e-06 26.1 0.0 10.1 8 3 3 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAN05126.1 - 1.4e-15 56.1 10.6 0.0057 16.7 0.0 12.4 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN05126.1 - 6.2e-14 52.4 1.1 0.0014 19.2 0.0 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN05126.1 - 6.4e-13 47.8 4.2 0.073 13.3 0.0 8.7 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN05126.1 - 2e-12 46.6 0.2 0.057 13.8 0.0 10.0 11 1 1 12 12 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN05126.1 - 7.2e-12 44.8 0.0 0.00033 20.3 0.0 6.2 7 0 0 7 7 7 2 TPR repeat TPR_1 PF00515.28 GAN05126.1 - 4.8e-09 35.7 0.0 0.048 13.5 0.0 5.7 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN05126.1 - 6.5e-09 35.9 6.3 4.1 8.3 0.0 9.9 12 1 0 12 12 10 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAN05126.1 - 7.3e-08 32.3 6.0 0.028 14.2 1.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 GAN05126.1 - 2.4e-05 24.6 3.7 1.1 9.6 0.0 6.5 6 2 1 7 7 6 1 Tetratricopeptide repeat NARP1 PF12569.8 GAN05126.1 - 4.7e-05 22.5 8.8 0.011 14.6 0.0 4.9 4 1 1 6 6 6 2 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 GAN05126.1 - 6.4e-05 23.1 0.5 4.6 7.5 0.0 4.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 GAN05126.1 - 0.0002 21.3 0.9 6.2 6.7 0.0 3.8 3 0 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 GAN05126.1 - 0.00084 19.4 1.2 4.1 7.6 0.0 5.7 6 1 0 6 6 6 1 Tetratricopeptide repeat DUF3808 PF10300.9 GAN05126.1 - 0.0011 17.7 0.3 0.55 8.9 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3808) FAT PF02259.23 GAN05126.1 - 0.0056 16.0 12.8 0.41 9.8 0.4 4.1 2 1 1 3 3 3 2 FAT domain Suf PF05843.14 GAN05126.1 - 0.1 12.5 1.8 7.1 6.5 0.0 4.3 7 0 0 7 7 7 0 Suppressor of forked protein (Suf) DUF2786 PF10979.8 GAN05126.1 - 1.1 9.2 4.7 5.7 6.9 0.1 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF2786) RA PF00788.23 GAN05127.1 - 5.8e-10 39.7 5.3 4.4e-06 27.2 0.0 3.0 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 GAN05127.1 - 2.6e-06 26.9 0.1 7.4e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAN05127.1 - 0.0064 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HigB-like_toxin PF05015.13 GAN05127.1 - 1.4 9.4 4.6 0.9 10.0 0.4 2.8 3 0 0 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB SMAP PF15477.6 GAN05128.1 - 2.2e-15 57.3 2.5 2.2e-15 57.3 2.5 2.8 2 1 0 2 2 2 1 Small acidic protein family Presenilin PF01080.17 GAN05128.1 - 0.32 9.7 12.4 0.28 9.9 12.4 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GAN05128.1 - 1.1 8.4 10.8 1.1 8.4 10.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LAP1C PF05609.12 GAN05128.1 - 3.2 6.7 18.1 3.8 6.5 18.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2151 PF10221.9 GAN05128.1 - 5.2 5.5 17.0 6 5.3 17.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator NPR3 PF03666.13 GAN05128.1 - 6 5.6 22.9 6.4 5.4 22.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5427 PF10310.9 GAN05128.1 - 9.8 5.0 22.8 13 4.6 22.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Mt_ATP-synt_B PF05405.14 GAN05129.1 - 1.8e-47 161.0 9.6 2.7e-47 160.4 9.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5623 PF18536.1 GAN05129.1 - 0.0054 17.0 1.1 0.014 15.7 0.4 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF5623) DUF1539 PF07560.11 GAN05129.1 - 0.012 15.7 3.3 0.022 14.8 3.3 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) COMPASS-Shg1 PF05205.12 GAN05129.1 - 1.3 9.7 8.0 15 6.3 1.3 2.5 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 WD40 PF00400.32 GAN05130.1 - 1.5e-37 126.9 27.1 6.9e-09 36.2 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05130.1 - 1.3e-17 63.8 3.2 0.001 19.3 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN05130.1 - 3.6e-12 46.2 0.0 1.6e-05 24.4 0.0 3.3 1 1 2 3 3 3 3 WD40-like domain eIF2A PF08662.11 GAN05130.1 - 6.7e-08 32.6 0.3 0.0014 18.6 0.1 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAN05130.1 - 4.8e-07 28.8 2.8 0.0068 15.1 0.2 3.6 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN05130.1 - 0.00037 19.6 5.8 0.033 13.2 0.0 4.0 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DJ-1_PfpI PF01965.24 GAN05130.1 - 0.015 15.1 0.8 0.3 10.9 0.3 2.5 2 1 0 2 2 2 0 DJ-1/PfpI family DUF1513 PF07433.11 GAN05130.1 - 0.086 11.9 0.7 21 4.0 0.0 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF1513) Pkinase PF00069.25 GAN05131.1 - 1.3e-26 93.6 0.2 4.8e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05131.1 - 6.2e-13 48.6 0.3 1.1e-12 47.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN05131.1 - 3.2e-10 39.4 1.3 4.3e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAN05131.1 - 0.00048 20.1 3.9 0.006 16.5 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family DivIC PF04977.15 GAN05131.1 - 0.76 9.6 9.2 2.3 8.0 9.2 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 GAN05131.1 - 0.92 8.8 4.9 1.5 8.1 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) His_Phos_1 PF00300.22 GAN05132.1 - 1.3e-21 77.2 0.0 1.6e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Complex1_LYR_2 PF13233.6 GAN05133.1 - 7.8e-25 87.4 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAN05133.1 - 7.6e-12 45.1 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) T4SS_TraI PF16932.5 GAN05133.1 - 0.00095 18.4 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system, conjugal DNA-protein transfer Complex1_LYR_1 PF13232.6 GAN05133.1 - 0.11 13.1 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like PGM_PMM_I PF02878.16 GAN05134.1 - 1.5e-41 141.3 0.0 3.6e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAN05134.1 - 1.7e-23 83.2 0.0 4.9e-23 81.7 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAN05134.1 - 9e-14 51.6 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GAN05134.1 - 1.4e-05 25.2 0.0 4.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain STAG PF08514.11 GAN05135.1 - 1.2e-34 118.7 9.4 1.2e-34 118.6 3.9 3.4 3 0 0 3 3 3 1 STAG domain HEAT PF02985.22 GAN05135.1 - 0.0068 16.6 0.1 11 6.6 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat TFIIA PF03153.13 GAN05135.1 - 3.5 7.5 15.3 0.92 9.4 6.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SPATA3 PF15662.5 GAN05135.1 - 3.6 8.2 7.0 8.8 6.9 7.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Pinin_SDK_N PF04697.13 GAN05135.1 - 4.1 8.0 10.3 6.4 7.4 0.2 2.9 2 0 0 2 2 2 0 pinin/SDK conserved region Cytochrom_B_C PF00032.17 GAN05136.1 - 0.2 12.0 3.6 0.2 12.0 1.9 2.0 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD RabGAP-TBC PF00566.18 GAN05137.1 - 1.3e-37 129.6 3.0 1.3e-37 129.6 3.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3231 PF11553.8 GAN05137.1 - 0.0045 16.6 0.2 0.011 15.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3231) DUF1325 PF07039.11 GAN05138.1 - 7.9e-38 129.5 0.3 1.3e-37 128.9 0.3 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 GAN05138.1 - 0.0011 18.8 0.4 0.0048 16.7 0.1 2.1 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain FAM193_C PF15914.5 GAN05138.1 - 0.017 14.8 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 FAM193 family C-terminal LBR_tudor PF09465.10 GAN05138.1 - 0.019 14.8 0.3 0.43 10.4 0.0 2.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain TUDOR PF00567.24 GAN05138.1 - 0.024 14.7 0.1 0.35 10.9 0.0 2.6 2 1 1 3 3 3 0 Tudor domain DUF4819 PF16090.5 GAN05138.1 - 0.046 13.8 1.0 0.28 11.3 0.1 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4819) TUDOR_5 PF18359.1 GAN05138.1 - 0.13 12.0 0.7 0.47 10.2 0.2 2.3 2 1 1 3 3 3 0 Histone methyltransferase Tudor domain 1 CotH PF08757.11 GAN05139.1 - 4.9e-26 92.0 9.5 7.6e-26 91.4 9.5 1.2 1 0 0 1 1 1 1 CotH kinase protein HapK PF11639.8 GAN05139.1 - 0.076 13.5 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 REDY-like protein HapK DUF3123 PF11321.8 GAN05139.1 - 2.5 8.8 5.5 5.2 7.8 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF4200 PF13863.6 GAN05140.1 - 0.068 13.6 2.9 0.12 12.8 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spectrin PF00435.21 GAN05140.1 - 0.077 13.5 4.2 29 5.2 0.0 3.0 2 1 1 3 3 3 0 Spectrin repeat DUF3519 PF12033.8 GAN05140.1 - 0.22 11.9 3.8 3.1 8.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) DUF1664 PF07889.12 GAN05140.1 - 0.76 9.8 4.2 1.3 9.0 2.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAN05140.1 - 0.97 9.5 6.2 2.5 8.1 4.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LrgB PF04172.16 GAN05141.1 - 4.6e-39 134.2 10.9 9.5e-39 133.1 10.9 1.5 1 0 0 1 1 1 1 LrgB-like family LrgA PF03788.14 GAN05141.1 - 8.5e-10 38.5 3.1 8.5e-10 38.5 3.1 2.6 2 0 0 2 2 2 1 LrgA family zf-RING_2 PF13639.6 GAN05142.1 - 1.1e-07 32.0 4.5 2.5e-07 30.9 4.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAN05142.1 - 3.3e-05 24.1 2.5 7.6e-05 22.9 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAN05142.1 - 3.7e-05 23.4 3.0 7.8e-05 22.3 3.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAN05142.1 - 6.2e-05 22.9 2.9 0.00012 22.0 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAN05142.1 - 0.00029 20.6 5.4 0.00054 19.8 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN05142.1 - 0.00083 19.2 4.5 0.0017 18.1 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN05142.1 - 0.0019 18.1 5.4 0.0038 17.2 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN05142.1 - 0.1 12.5 4.5 0.18 11.7 4.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN05142.1 - 0.12 12.4 1.5 0.36 10.9 1.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAN05142.1 - 0.68 9.9 4.9 1.4 8.9 4.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN05143.1 - 1.5e-09 38.0 3.8 2.6e-09 37.2 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 GAN05143.1 - 5.7e-08 32.4 1.1 5.7e-08 32.4 1.1 2.4 3 0 0 3 3 3 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 GAN05143.1 - 2.7e-07 30.3 2.4 4.7e-07 29.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN05143.1 - 5.9e-07 29.4 2.8 1.2e-06 28.4 2.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAN05143.1 - 4.4e-06 26.3 1.8 9.6e-06 25.2 1.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAN05143.1 - 1.1e-05 25.2 1.8 2e-05 24.4 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN05143.1 - 1.5e-05 24.8 2.0 2.6e-05 24.1 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAN05143.1 - 2.4e-05 24.5 2.0 5.8e-05 23.3 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAN05143.1 - 0.0001 22.1 2.2 0.00019 21.2 2.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAN05143.1 - 0.00029 20.6 2.4 0.00046 20.0 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 GAN05143.1 - 0.0011 18.7 0.8 0.0023 17.7 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 GAN05143.1 - 0.0065 16.3 2.8 0.014 15.3 2.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein ATG16 PF08614.11 GAN05143.1 - 0.007 16.6 11.1 0.007 16.6 11.1 3.1 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) DivIC PF04977.15 GAN05143.1 - 0.017 14.9 0.9 0.017 14.9 0.9 5.4 4 2 1 5 5 5 0 Septum formation initiator zf-UDP PF14569.6 GAN05143.1 - 0.031 14.4 0.4 0.056 13.6 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF1178 PF06676.11 GAN05143.1 - 0.055 13.8 0.8 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-RING_4 PF14570.6 GAN05143.1 - 0.1 12.4 2.5 0.2 11.5 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain V-SNARE_C PF12352.8 GAN05143.1 - 0.17 12.2 6.9 1.9 8.8 0.6 2.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Tweety PF04906.13 GAN05143.1 - 0.19 10.3 2.9 0.19 10.4 0.3 2.2 2 0 0 2 2 2 0 Tweety NAS PF03059.16 GAN05143.1 - 0.3 10.4 2.6 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 Nicotianamine synthase protein zf-C3HC4_4 PF15227.6 GAN05143.1 - 0.34 11.1 2.5 1.3 9.2 2.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 GAN05143.1 - 3 7.9 5.5 0.81 9.7 0.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Sec20 PF03908.13 GAN05143.1 - 3.1 7.8 9.2 17 5.4 2.5 3.2 1 1 1 2 2 2 0 Sec20 DUF948 PF06103.11 GAN05143.1 - 4.7 7.5 8.0 1.5 9.1 3.5 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cep57_CLD_2 PF14197.6 GAN05143.1 - 5.2 7.2 21.2 0.045 13.9 7.6 3.6 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 LemA PF04011.12 GAN05143.1 - 5.3 6.9 13.6 0.26 11.1 0.2 3.5 2 1 1 4 4 4 0 LemA family RIC3 PF15361.6 GAN05143.1 - 7.3 7.0 6.9 0.39 11.1 0.2 2.3 3 0 0 3 3 2 0 Resistance to inhibitors of cholinesterase homologue 3 Fez1 PF06818.15 GAN05143.1 - 7.7 6.9 34.8 20 5.6 3.8 3.1 1 1 2 3 3 3 0 Fez1 TACC_C PF05010.14 GAN05143.1 - 9.4 6.0 28.2 0.021 14.6 4.5 3.4 2 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-RING_2 PF13639.6 GAN05144.1 - 0.0018 18.6 0.2 0.0025 18.1 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN05144.1 - 0.023 14.4 0.3 0.048 13.4 0.3 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 GAN05144.1 - 0.043 13.9 0.2 0.072 13.1 0.2 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAN05144.1 - 0.072 13.1 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain G6PD_C PF02781.16 GAN05145.1 - 5.9e-114 380.2 0.0 8.4e-114 379.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAN05145.1 - 1.6e-58 198.2 0.6 5.1e-58 196.6 0.0 2.1 3 0 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain SANT_DAMP1_like PF16282.5 GAN05146.1 - 8.6e-23 80.3 2.1 2e-22 79.2 2.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 GAN05146.1 - 3.1e-08 33.7 1.9 1.1e-07 31.9 1.9 2.0 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DMAP1_like PF17024.5 GAN05146.1 - 2.5e-06 27.6 0.5 1.4e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 Putative DMAP1-like RNA_pol_3_Rpc31 PF11705.8 GAN05146.1 - 0.011 16.1 5.4 0.011 16.1 5.4 3.8 4 1 0 4 4 4 0 DNA-directed RNA polymerase III subunit Rpc31 Myb_DNA-bind_6 PF13921.6 GAN05146.1 - 0.011 15.9 0.9 0.036 14.3 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Sec39 PF08314.11 GAN05147.1 - 7.9e-110 368.5 0.3 1e-109 368.1 0.3 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Phage_integrase PF00589.22 GAN05148.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family RVT_1 PF00078.27 GAN05150.1 - 1.7e-05 24.5 0.1 4.4e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 GAN05151.1 - 2.5e-33 115.9 0.2 8.9e-23 81.2 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN05151.1 - 3.8e-08 33.8 0.1 1.4e-05 25.4 0.1 3.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAN05152.1 - 6.5e-29 101.3 0.0 1.5e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN05152.1 - 2.6e-11 44.1 0.2 4.9e-10 39.9 0.2 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Amidohydro_1 PF01979.20 GAN05153.1 - 3.4e-37 128.5 0.1 4.2e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAN05153.1 - 1.7e-12 47.5 0.1 1.9e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family zf-RING_2 PF13639.6 GAN05154.1 - 4.7e-09 36.4 6.7 8.5e-09 35.6 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN05154.1 - 4.8e-07 29.4 0.7 1.1e-06 28.2 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GAN05154.1 - 1.1e-06 28.5 6.6 1.9e-06 27.7 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAN05154.1 - 1.6e-06 28.0 1.4 6e-06 26.2 0.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAN05154.1 - 2.4e-06 27.8 3.7 5.7e-06 26.5 3.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAN05154.1 - 1.7e-05 24.5 7.7 4.2e-05 23.3 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN05154.1 - 2.5e-05 24.0 7.7 4.9e-05 23.1 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.12 GAN05154.1 - 0.00016 22.2 12.0 0.0031 18.1 0.4 5.2 4 1 0 5 5 5 1 SlyX zf-C3HC4_3 PF13920.6 GAN05154.1 - 0.00019 21.2 5.4 0.00031 20.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.9 GAN05154.1 - 0.00067 19.7 28.4 0.024 14.6 2.0 4.0 3 1 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MIF4G_like_2 PF09090.11 GAN05154.1 - 0.0071 15.8 4.6 0.0071 15.8 4.6 2.0 1 1 1 2 2 2 1 MIF4G like KASH_CCD PF14662.6 GAN05154.1 - 0.018 14.9 24.0 0.14 12.0 3.3 3.2 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH zf-RING_6 PF14835.6 GAN05154.1 - 0.021 14.7 3.2 0.04 13.8 3.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 GAN05154.1 - 0.022 14.6 6.6 0.042 13.7 6.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DHR10 PF18595.1 GAN05154.1 - 0.052 13.6 28.3 0.46 10.5 0.6 4.0 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain PilJ PF13675.6 GAN05154.1 - 0.25 11.4 4.7 0.49 10.4 0.2 3.2 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Golgin_A5 PF09787.9 GAN05154.1 - 0.49 9.8 20.8 2.1 7.8 9.4 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 YjcZ PF13990.6 GAN05154.1 - 0.55 9.6 6.1 0.59 9.5 1.0 2.2 2 0 0 2 2 2 0 YjcZ-like protein Prok-RING_1 PF14446.6 GAN05154.1 - 0.68 9.9 6.2 1.7 8.6 1.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF4407 PF14362.6 GAN05154.1 - 0.73 9.1 15.9 0.89 8.9 7.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-ANAPC11 PF12861.7 GAN05154.1 - 0.73 9.9 4.1 0.54 10.4 2.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fib_alpha PF08702.10 GAN05154.1 - 0.98 9.6 19.5 1.2 9.3 8.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 GAN05154.1 - 1.5 8.9 17.8 6.2 6.9 3.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1272 PF06906.11 GAN05154.1 - 2 8.6 7.1 4.8 7.4 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) BLOC1_2 PF10046.9 GAN05154.1 - 2.3 8.6 23.7 1.4 9.2 2.8 4.1 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 GAN05154.1 - 2.3 8.3 37.5 5.2 7.1 13.6 3.8 3 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 GAN05154.1 - 5.2 6.9 26.4 1.4 8.8 2.5 5.3 3 2 3 6 6 6 0 Septum formation initiator DUF16 PF01519.16 GAN05154.1 - 8.9 6.9 21.6 1.9 9.0 6.8 3.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 ETF_QO PF05187.13 GAN05155.1 - 1.8e-49 166.2 0.1 3e-49 165.5 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 GAN05155.1 - 3.2e-08 33.5 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAN05155.1 - 8e-08 31.8 0.4 0.00078 18.6 1.3 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 GAN05155.1 - 5.5e-07 30.1 0.3 0.061 13.9 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN05155.1 - 8.9e-07 29.0 0.0 4.3e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAN05155.1 - 1e-06 28.2 0.0 0.00098 18.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.7 GAN05155.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN05155.1 - 4.3e-05 22.9 0.1 0.00013 21.4 0.1 1.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN05155.1 - 7.9e-05 21.5 0.3 0.00015 20.7 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 GAN05155.1 - 8.9e-05 22.5 0.4 0.00024 21.1 0.4 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAN05155.1 - 0.00021 20.3 0.1 0.0096 14.8 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 GAN05155.1 - 0.00032 20.1 0.2 0.00051 19.4 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 GAN05155.1 - 0.0004 20.9 1.1 0.00092 19.7 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 GAN05155.1 - 0.014 14.6 0.3 0.023 14.0 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAN05155.1 - 0.052 12.6 0.3 0.074 12.1 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_10 PF13237.6 GAN05155.1 - 0.08 13.1 0.6 0.2 11.8 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAN05155.1 - 0.16 12.1 0.6 0.45 10.7 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 GAN05155.1 - 0.29 10.2 0.6 0.42 9.7 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NUDIX PF00293.28 GAN05156.1 - 1.2e-16 61.0 1.2 1.6e-16 60.5 1.2 1.1 1 0 0 1 1 1 1 NUDIX domain MAGE PF01454.19 GAN05158.1 - 2.9e-47 161.1 0.2 4e-47 160.7 0.2 1.2 1 0 0 1 1 1 1 MAGE family Endonuc_Holl PF10107.9 GAN05158.1 - 0.13 12.1 0.2 0.26 11.1 0.1 1.6 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase HIT PF01230.23 GAN05159.1 - 4.8e-21 75.3 0.0 7.4e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAN05159.1 - 5.7e-08 33.2 0.0 9.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 GAN05159.1 - 0.045 13.5 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain His_biosynth PF00977.21 GAN05160.1 - 4.9e-33 114.5 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein CLTH PF10607.9 GAN05161.1 - 1.9e-37 128.5 0.3 2.4e-37 128.1 0.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAN05161.1 - 7.5e-11 41.6 0.1 3.3e-10 39.5 0.1 2.1 3 0 0 3 3 3 1 LisH DUF4984 PF16372.5 GAN05161.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4984) GATA PF00320.27 GAN05162.1 - 3.8e-14 52.0 5.3 8.1e-14 50.9 5.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 GAN05162.1 - 3.2 7.9 7.6 0.35 10.9 1.0 2.7 3 0 0 3 3 3 0 Double zinc ribbon Ribosomal_L37ae PF01780.19 GAN05162.1 - 8.8 6.5 6.9 4.4 7.5 2.3 2.5 2 1 1 3 3 3 0 Ribosomal L37ae protein family CENP-L PF13092.6 GAN05163.1 - 3.8e-11 43.5 0.2 2.1e-10 41.0 0.2 2.3 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Abhydrolase_1 PF00561.20 GAN05164.1 - 8.8e-12 45.2 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN05164.1 - 1.2e-06 28.0 0.0 2.4e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN05164.1 - 0.00018 22.2 0.0 0.00036 21.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.8 GAN05164.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Palm_thioest PF02089.15 GAN05164.1 - 0.045 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Poty_PP PF08440.10 GAN05164.1 - 0.1 11.6 0.0 0.6 9.2 0.0 2.0 1 1 1 2 2 2 0 Potyviridae polyprotein Solute_trans_a PF03619.16 GAN05165.1 - 3.3e-43 148.1 14.0 4.6e-43 147.7 14.0 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha S_4TM PF18159.1 GAN05165.1 - 0.029 13.7 0.3 0.09 12.1 0.1 1.9 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain bZIP_1 PF00170.21 GAN05166.1 - 2.1e-13 50.2 11.4 2.1e-13 50.2 11.4 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAN05166.1 - 4.7e-08 33.0 12.1 4.7e-08 33.0 12.1 2.3 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAN05166.1 - 0.00047 20.6 8.1 0.00047 20.6 8.1 2.1 2 1 1 3 3 3 1 bZIP Maf transcription factor Chibby PF14645.6 GAN05166.1 - 0.0093 16.4 5.8 0.019 15.3 5.8 1.5 1 0 0 1 1 1 1 Chibby family LAP1C PF05609.12 GAN05166.1 - 0.054 12.6 9.1 0.059 12.5 9.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) VIR_N PF15912.5 GAN05166.1 - 0.18 11.4 8.7 0.23 11.0 8.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4485 PF14846.6 GAN05166.1 - 0.22 11.6 3.4 0.52 10.4 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) SR-25 PF10500.9 GAN05166.1 - 1.9 8.0 21.8 3.1 7.4 21.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 GAN05166.1 - 4.7 5.9 7.3 5.7 5.6 7.3 1.2 1 0 0 1 1 1 0 Presenilin DUF5094 PF17015.5 GAN05166.1 - 8.6 6.4 13.2 14 5.8 13.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) p450 PF00067.22 GAN05167.1 - 3.7e-73 246.9 0.0 4.8e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 GAN05168.1 - 5e-62 210.2 0.0 5.9e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAN05168.1 - 0.0033 16.0 0.0 0.0071 14.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAN05168.1 - 0.017 14.1 0.0 0.035 13.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Alliinase_C PF04864.13 GAN05168.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Allinase PC4 PF02229.16 GAN05169.1 - 4e-07 29.6 0.0 6.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) BLOC1_2 PF10046.9 GAN05170.1 - 9.6e-25 86.7 12.2 1.4e-24 86.2 12.2 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1241 PF06840.11 GAN05170.1 - 0.00012 21.7 1.4 0.00013 21.6 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Fzo_mitofusin PF04799.13 GAN05170.1 - 0.065 12.8 6.3 0.087 12.4 6.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region Hrs_helical PF12210.8 GAN05170.1 - 0.067 13.7 3.9 0.13 12.8 3.7 1.7 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MRP-L51 PF10244.9 GAN05170.1 - 0.085 13.1 0.9 0.15 12.3 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit LOH1CR12 PF10158.9 GAN05170.1 - 0.15 12.1 5.6 0.3 11.1 5.6 1.7 1 1 0 1 1 1 0 Tumour suppressor protein DUF4200 PF13863.6 GAN05170.1 - 0.23 11.9 11.1 1.3 9.5 11.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3417 PF11897.8 GAN05170.1 - 0.28 11.7 5.1 1.9 9.0 5.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) FapA PF03961.13 GAN05170.1 - 0.45 9.1 6.1 0.53 8.8 6.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 GAN05170.1 - 0.46 10.0 5.6 0.52 9.8 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1043 PF06295.12 GAN05170.1 - 0.85 9.6 9.7 1.1 9.3 8.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Fib_alpha PF08702.10 GAN05170.1 - 0.93 9.7 9.5 0.46 10.7 6.2 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fes1 PF08609.10 GAN05170.1 - 1.6 9.6 8.7 5.8 7.9 6.1 2.5 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 RRP36 PF06102.12 GAN05170.1 - 4.7 7.1 9.3 22 5.0 9.3 1.9 1 1 0 1 1 1 0 rRNA biogenesis protein RRP36 Aminotran_3 PF00202.21 GAN05171.1 - 2.5e-120 401.9 0.0 3.1e-120 401.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAN05171.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Serine_rich PF08824.10 GAN05171.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Serine rich protein interaction domain Use1 PF09753.9 GAN05172.1 - 2.4e-23 83.2 14.5 3.5e-21 76.1 11.7 2.3 2 1 0 2 2 2 2 Membrane fusion protein Use1 Neur_chan_memb PF02932.16 GAN05172.1 - 0.02 15.0 2.0 0.029 14.4 2.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 GAN05172.1 - 0.091 11.0 9.7 0.11 10.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 GAN05172.1 - 0.14 10.6 12.6 0.18 10.3 12.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Hpt PF01627.23 GAN05173.1 - 3.1e-12 46.6 0.1 5.6e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Hpt domain G-patch PF01585.23 GAN05174.1 - 3e-17 62.2 0.4 6.9e-17 61.1 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN05174.1 - 2.3e-08 34.0 0.1 2.3e-08 34.0 0.1 3.1 3 0 0 3 3 3 1 G-patch domain GlutR_dimer PF00745.20 GAN05174.1 - 0.053 14.0 0.6 0.053 14.0 0.6 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain GPI-anchored PF10342.9 GAN05175.1 - 1.6e-14 54.4 0.3 1.6e-14 54.4 0.3 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Melittin PF01372.17 GAN05175.1 - 0.13 12.3 0.3 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Melittin PAP_central PF04928.17 GAN05176.1 - 2.7e-38 131.4 0.0 4.1e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAN05176.1 - 1.3e-14 54.2 0.6 2.2e-14 53.4 0.6 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAN05176.1 - 0.00018 21.7 0.0 0.00053 20.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain SurA_N_2 PF13623.6 GAN05177.1 - 0.023 14.6 0.0 3.3 7.6 0.1 2.2 1 1 0 2 2 2 0 SurA N-terminal domain HTH_32 PF13565.6 GAN05177.1 - 0.038 14.6 0.6 0.25 12.0 0.1 2.1 1 1 1 2 2 2 0 Homeodomain-like domain Zincin_1 PF06262.11 GAN05177.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase Zip PF02535.22 GAN05178.1 - 3.1e-51 174.6 11.5 3.9e-51 174.3 11.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter ChaC PF04752.12 GAN05179.1 - 2.6e-63 213.3 1.2 1.2e-35 123.2 0.5 2.1 1 1 1 2 2 2 2 ChaC-like protein VTC PF09359.10 GAN05180.1 - 1.5e-25 90.1 0.1 2.8e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 VTC domain Snf7 PF03357.21 GAN05181.1 - 3.9e-13 49.4 16.7 4.5e-13 49.1 16.1 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 GAN05181.1 - 0.00056 19.9 2.2 0.00083 19.3 2.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway LRR_6 PF13516.6 GAN05183.1 - 1.7e-12 46.3 13.8 0.048 13.7 0.1 6.9 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 GAN05183.1 - 2.3e-08 34.2 16.1 0.01 16.2 1.0 6.6 4 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN05183.1 - 2.3e-07 30.4 2.3 2.7 8.9 0.0 6.8 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 GAN05183.1 - 0.00034 20.3 12.6 0.79 9.5 0.4 6.0 5 1 1 6 6 6 2 Leucine rich repeat Nop16 PF09420.10 GAN05183.1 - 0.079 13.0 8.7 0.16 12.0 8.7 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Drc1-Sld2 PF11719.8 GAN05183.1 - 0.54 9.7 6.0 9.1 5.7 7.8 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein PTPRCAP PF15713.5 GAN05183.1 - 8.8 6.6 15.4 17 5.7 15.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CENP-B_dimeris PF09026.10 GAN05185.1 - 0.015 15.7 9.8 0.015 15.7 9.8 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain GCIP PF13324.6 GAN05185.1 - 0.13 11.8 0.5 0.25 10.9 0.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GAN05185.1 - 6.1 4.8 8.0 11 4.0 8.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L22e PF01776.17 GAN05186.1 - 1e-49 167.5 1.9 1.2e-49 167.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family PsaL PF02605.15 GAN05187.1 - 0.002 17.8 0.1 0.0033 17.1 0.1 1.6 1 1 0 1 1 1 1 Photosystem I reaction centre subunit XI WD40 PF00400.32 GAN05188.1 - 2.7e-08 34.3 2.7 0.025 15.4 0.4 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 GAN05188.1 - 0.012 14.3 0.1 2.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF4131 PF13567.6 GAN05188.1 - 0.86 9.2 2.3 0.94 9.1 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Kelch_6 PF13964.6 GAN05189.1 - 8.9e-16 57.5 4.6 0.013 15.8 0.1 6.6 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 GAN05189.1 - 9.3e-16 57.7 7.8 3.4e-05 24.0 0.3 7.1 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN05189.1 - 4.2e-14 52.1 1.8 0.00013 21.8 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAN05189.1 - 1.1e-10 41.1 5.6 0.016 15.1 0.2 6.2 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.25 GAN05189.1 - 2e-10 40.1 7.8 0.00021 20.8 0.1 6.3 6 1 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 GAN05189.1 - 2.3e-10 40.3 16.3 0.039 14.0 0.4 7.2 7 1 0 7 7 7 3 Galactose oxidase, central domain LRR_10 PF18805.1 GAN05189.1 - 0.015 15.0 0.2 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat ASC PF00858.24 GAN05189.1 - 0.041 12.8 1.2 0.054 12.4 0.1 1.7 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel DUF2371 PF10177.9 GAN05189.1 - 0.077 13.2 0.0 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Romo1 PF10247.9 GAN05189.1 - 0.25 11.8 3.5 14 6.1 0.1 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 zf-CCHC PF00098.23 GAN05190.1 - 7.9e-52 171.1 59.3 8.1e-09 35.2 2.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 GAN05190.1 - 1.1e-11 44.2 40.1 0.02 14.6 0.2 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 GAN05190.1 - 6e-08 32.5 45.3 0.093 12.7 0.9 7.1 1 1 6 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 GAN05190.1 - 0.00011 21.8 40.0 0.21 11.3 0.9 7.1 7 0 0 7 7 7 5 GAG-polyprotein viral zinc-finger Myc_N PF01056.18 GAN05190.1 - 0.019 14.9 5.0 0.027 14.4 4.7 1.4 1 1 0 1 1 1 0 Myc amino-terminal region zf-CCHC_2 PF13696.6 GAN05190.1 - 0.08 12.8 0.6 0.08 12.8 0.6 7.4 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.6 GAN05190.1 - 0.4 10.6 44.4 0.58 10.1 1.2 7.0 5 2 2 7 7 7 0 Zinc knuckle PBP1_TM PF14812.6 GAN05190.1 - 5.6 7.4 12.3 0.29 11.5 7.0 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NinE PF05322.11 GAN05190.1 - 7.4 6.5 6.3 39 4.2 0.4 3.5 3 0 0 3 3 3 0 NINE Protein CDC45 PF02724.14 GAN05190.1 - 9.2 4.4 9.6 36 2.4 9.3 1.8 2 0 0 2 2 2 0 CDC45-like protein tRNA_int_end_N2 PF12928.7 GAN05191.1 - 1.8e-05 24.8 0.0 3.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 GAN05191.1 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain HTH_33 PF13592.6 GAN05191.1 - 0.096 12.3 2.3 8.2 6.2 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn helix RRM_1 PF00076.22 GAN05192.1 - 5.4e-18 64.6 0.0 9.9e-18 63.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAN05192.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GAN05192.1 - 0.002 18.6 19.4 0.002 18.6 19.4 4.4 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Glyco_hydro_47 PF01532.20 GAN05194.1 - 2.8e-140 468.2 0.3 3.2e-140 468.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 GAN05194.1 - 0.074 11.5 0.0 3.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Sugar_tr PF00083.24 GAN05195.1 - 2e-99 333.5 17.1 5.5e-99 332.1 17.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN05195.1 - 9.4e-31 107.0 43.6 4.3e-27 95.0 14.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN05195.1 - 0.0003 19.3 1.3 0.0003 19.3 1.3 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4381 PF14316.6 GAN05195.1 - 0.064 13.5 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Myb_Cef PF11831.8 GAN05196.1 - 6.1e-37 127.5 9.3 6.1e-37 127.5 9.3 3.9 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GAN05196.1 - 4.4e-23 81.2 5.1 1e-11 44.8 1.4 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN05196.1 - 2e-21 76.0 6.8 6.1e-14 52.0 3.5 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GAN05196.1 - 0.43 10.7 2.5 2 8.5 0.2 2.9 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAM193_C PF15914.5 GAN05196.1 - 0.99 9.2 6.8 1.3 8.8 0.3 3.2 2 0 0 2 2 2 0 FAM193 family C-terminal Gti1_Pac2 PF09729.9 GAN05197.1 - 1 9.4 12.8 1.2 9.1 12.8 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family Glyoxalase PF00903.25 GAN05198.1 - 1.8e-22 79.9 0.0 2.1e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAN05198.1 - 2.7e-09 37.3 0.0 1.6e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 GAN05198.1 - 5.6e-05 23.0 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 GAN05198.1 - 0.00041 21.1 0.0 0.001 19.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 GAN05198.1 - 0.004 17.3 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain PX PF00787.24 GAN05199.1 - 3.1e-06 27.1 0.0 7.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 GAN05199.1 - 0.026 14.4 0.4 0.1 12.6 0.0 2.2 3 0 0 3 3 3 0 PB1 domain UBX PF00789.20 GAN05201.1 - 4.6e-16 58.8 0.0 1.3e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 UBX domain ATP-synt_ab_N PF02874.23 GAN05202.1 - 5e-24 84.6 1.7 9.8e-24 83.7 1.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 GAN05202.1 - 1.7e-10 40.9 0.0 3.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 GAN05202.1 - 0.0061 15.8 0.1 0.0087 15.3 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAN05202.1 - 0.021 15.2 0.2 0.049 14.0 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 GAN05202.1 - 0.022 14.5 0.3 0.046 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAN05202.1 - 0.028 14.8 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAN05202.1 - 0.033 14.1 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 GAN05202.1 - 0.034 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAN05202.1 - 0.095 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAN05202.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CSD2 PF17876.1 GAN05202.1 - 0.1 12.8 0.5 0.47 10.7 0.4 2.1 2 0 0 2 2 2 0 Cold shock domain TrwB_AAD_bind PF10412.9 GAN05202.1 - 0.11 11.4 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 GAN05202.1 - 0.17 12.1 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAN05202.1 - 0.21 12.1 1.0 0.43 11.1 0.2 1.8 2 1 0 2 2 2 0 ABC transporter AA_kinase PF00696.28 GAN05203.1 - 8.2e-37 127.1 0.6 1.3e-36 126.4 0.6 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 GAN05203.1 - 0.0065 16.4 0.5 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 PUA domain Nucleotid_trans PF03407.16 GAN05203.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_hydro_72 PF03198.14 GAN05204.1 - 8.5e-134 445.7 1.7 1.1e-133 445.4 1.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 GAN05204.1 - 1.1e-12 48.5 0.9 3.4e-12 46.9 0.4 2.2 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 GAN05204.1 - 0.00033 20.2 0.3 0.0032 17.0 0.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 GAN05204.1 - 0.0063 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_cc PF11790.8 GAN05204.1 - 0.0073 15.9 0.0 0.028 14.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Pkinase PF00069.25 GAN05205.1 - 2e-73 247.0 0.0 4.8e-73 245.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05205.1 - 6.5e-39 133.8 0.0 1.1e-38 133.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAN05205.1 - 3.3e-11 42.8 0.1 6.5e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 GAN05205.1 - 9.2e-09 35.0 0.0 1.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN05205.1 - 0.0034 16.4 0.2 0.0085 15.1 0.2 1.6 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 GAN05205.1 - 0.0053 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAN05205.1 - 0.028 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN05205.1 - 0.028 13.8 0.1 0.092 12.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_T7_Capsid PF05396.11 GAN05205.1 - 9.5 6.6 8.3 1.3 9.4 0.0 3.4 3 0 0 3 3 3 0 Phage T7 capsid assembly protein Ribosomal_L4 PF00573.22 GAN05206.1 - 1.2e-41 142.5 0.9 1.2e-41 142.5 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAN05206.1 - 6.4e-13 48.6 8.4 6.7e-11 42.1 2.7 3.1 2 1 1 3 3 3 2 60S ribosomal protein L4 C-terminal domain Hydrolase_3 PF08282.12 GAN05207.1 - 2.3e-56 191.4 0.0 2.7e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAN05207.1 - 1.1e-12 48.0 0.0 9.2e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAN05207.1 - 5.1e-10 40.0 0.2 0.0025 18.1 0.0 3.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN05207.1 - 0.00079 19.9 0.3 6.5 7.1 0.0 3.7 2 1 2 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN05207.1 - 0.0015 18.6 0.0 0.36 10.9 0.0 3.2 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 GAN05207.1 - 0.003 16.7 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_6 PF13344.6 GAN05207.1 - 0.0076 16.3 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase C2 PF00168.30 GAN05209.1 - 4.4e-80 264.6 2.6 1.6e-19 70.1 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 GAN05209.1 - 5.3e-05 22.8 0.0 0.00015 21.3 0.0 1.8 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Homeodomain PF00046.29 GAN05210.1 - 2.2e-16 59.4 2.0 4.4e-16 58.5 2.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN05210.1 - 0.014 15.3 0.3 0.089 12.7 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain YdaS_antitoxin PF15943.5 GAN05210.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 GAN05210.1 - 0.033 14.0 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Thioredoxin PF00085.20 GAN05211.1 - 1.3e-08 34.8 0.0 1.5e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin Oxidored_FMN PF00724.20 GAN05212.1 - 2.4e-102 342.7 0.0 2.7e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NADH-u_ox-rdase PF10785.9 GAN05213.1 - 1.3e-28 99.4 1.5 9.4e-28 96.7 1.5 2.0 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 GAN05213.1 - 7.9e-19 67.4 0.1 1.1e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit F-box-like PF12937.7 GAN05214.1 - 2.8e-07 30.3 0.4 2.5e-06 27.3 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN05214.1 - 0.0037 17.1 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GAN05214.1 - 6.1 7.4 19.5 1.1 9.8 3.1 5.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) HsbA PF12296.8 GAN05215.1 - 1.3e-23 83.7 8.2 1.3e-23 83.7 8.2 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.12 GAN05215.1 - 0.049 14.1 1.5 11 6.6 0.0 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BRAP2 PF07576.12 GAN05216.1 - 1.6e-27 95.6 0.2 3.3e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 GAN05216.1 - 2.9e-18 65.9 4.4 2.9e-18 65.9 4.4 2.1 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 GAN05216.1 - 0.0014 18.9 12.6 0.0014 18.9 12.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN05216.1 - 0.0063 16.3 12.7 0.0063 16.3 12.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CENP-H PF05837.12 GAN05216.1 - 0.0086 16.5 7.0 0.024 15.0 7.0 1.7 1 0 0 1 1 1 1 Centromere protein H (CENP-H) TerY_C PF15616.6 GAN05216.1 - 0.011 15.8 3.9 0.011 15.8 3.9 2.9 2 1 1 3 3 3 0 TerY-C metal binding domain RRM_1 PF00076.22 GAN05216.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 GAN05216.1 - 0.043 13.7 23.4 0.038 13.9 9.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cortex-I_coil PF09304.10 GAN05216.1 - 0.17 12.1 9.8 0.08 13.2 7.0 1.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil LPP PF04728.13 GAN05216.1 - 0.22 11.9 2.8 1.1 9.7 2.8 2.2 1 1 0 1 1 1 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.19 GAN05216.1 - 0.24 9.3 3.6 0.37 8.7 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lectin_N PF03954.14 GAN05216.1 - 0.3 10.8 6.0 0.1 12.3 2.5 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain APG6_N PF17675.1 GAN05216.1 - 0.36 11.4 8.3 1.3 9.6 8.3 2.0 1 0 0 1 1 1 0 Apg6 coiled-coil region FliJ PF02050.16 GAN05216.1 - 0.91 9.8 8.0 2.2 8.5 8.0 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Prefoldin_2 PF01920.20 GAN05216.1 - 0.96 9.4 11.2 2.8 7.9 2.8 2.8 2 0 0 2 2 2 0 Prefoldin subunit EMP24_GP25L PF01105.24 GAN05216.1 - 1.2 9.1 5.1 0.98 9.3 0.8 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Got1 PF04178.12 GAN05217.1 - 6.3e-30 103.9 17.9 9.5e-30 103.3 17.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Xan_ur_permease PF00860.20 GAN05218.1 - 1.2e-82 277.7 39.9 1.5e-82 277.4 39.9 1.1 1 0 0 1 1 1 1 Permease family Atthog PF18800.1 GAN05218.1 - 0.19 11.6 9.6 1.3 8.9 2.0 2.4 2 0 0 2 2 2 0 Attenuator of Hedgehog EXS PF03124.14 GAN05219.1 - 1.1e-89 301.1 25.0 1.5e-89 300.6 25.0 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAN05219.1 - 1.8e-47 163.1 15.4 8.6e-25 88.5 6.7 2.5 1 1 1 2 2 2 2 SPX domain HTH_Tnp_Tc3_2 PF01498.18 GAN05220.1 - 1.6e-08 34.7 0.2 2.3e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.15 GAN05220.1 - 0.0091 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 GAN05220.1 - 0.019 14.5 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Cyclin_N PF00134.23 GAN05221.1 - 5.2e-16 58.5 0.0 7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN05221.1 - 2.9e-07 31.0 0.0 3.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin NAD_binding_10 PF13460.6 GAN05222.1 - 1.9e-20 73.5 0.0 2.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN05222.1 - 3.8e-05 23.3 0.3 7.8e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 GAN05222.1 - 0.00053 20.1 0.2 0.0009 19.4 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 GAN05222.1 - 0.0017 18.9 0.6 0.0036 17.9 0.6 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAN05222.1 - 0.014 15.8 0.5 0.043 14.2 0.4 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAN05222.1 - 0.021 14.7 0.3 0.038 13.9 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAN05222.1 - 0.027 13.9 0.1 0.051 13.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 GAN05222.1 - 0.034 13.9 0.2 0.051 13.3 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RmlD_sub_bind PF04321.17 GAN05222.1 - 0.045 12.8 0.2 0.091 11.8 0.1 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Rep_1 PF01446.17 GAN05222.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein Shugoshin_N PF07558.11 GAN05222.1 - 0.14 12.0 1.3 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Pkinase PF00069.25 GAN05223.1 - 2e-72 243.8 0.0 2.7e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05223.1 - 4.6e-33 114.6 0.0 6.6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Urm1 PF09138.11 GAN05223.1 - 1.3e-32 112.0 0.6 2.5e-32 111.1 0.6 1.5 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Pkinase_C PF00433.24 GAN05223.1 - 8.6e-11 42.4 4.3 8.6e-11 42.4 4.3 2.5 3 0 0 3 3 3 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAN05223.1 - 5.4e-06 25.6 0.0 8.9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain ThiS PF02597.20 GAN05223.1 - 0.024 15.2 0.1 0.064 13.9 0.1 1.7 1 0 0 1 1 1 0 ThiS family C2 PF00168.30 GAN05223.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain Cnn_1N PF07989.11 GAN05224.1 - 1e-09 38.4 9.4 2e-09 37.5 9.4 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 GAN05224.1 - 0.014 15.5 1.6 0.02 15.0 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SIKE PF05769.11 GAN05224.1 - 0.016 15.1 3.3 0.84 9.5 4.2 2.2 1 1 1 2 2 2 0 SIKE family Nas2_N PF18265.1 GAN05224.1 - 0.061 13.3 1.9 0.12 12.3 1.9 1.5 1 0 0 1 1 1 0 Nas2 N_terminal domain MCC-bdg_PDZ PF10506.9 GAN05224.1 - 0.21 11.6 2.8 1.7 8.7 0.6 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APC_N_CC PF16689.5 GAN05224.1 - 0.25 11.4 4.4 0.38 10.8 1.1 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_1 PF00170.21 GAN05224.1 - 0.36 10.9 8.3 1.6 8.9 0.7 2.5 1 1 1 2 2 2 0 bZIP transcription factor DUF2730 PF10805.8 GAN05224.1 - 1.3 9.2 6.1 2 8.5 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DASH_Hsk3 PF08227.11 GAN05224.1 - 1.6 9.1 6.5 0.19 12.1 1.8 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like PDEase_I PF00233.19 GAN05225.1 - 7.7e-75 251.7 2.1 2.3e-74 250.1 0.0 2.6 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 GAN05225.1 - 6.9e-05 23.0 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Spt20 PF12090.8 GAN05225.1 - 0.0017 18.0 2.1 0.0037 16.9 2.1 1.5 1 0 0 1 1 1 1 Spt20 family Roughex PF06020.11 GAN05225.1 - 0.87 8.6 3.9 1.5 7.8 3.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 GAN05225.1 - 1.3 10.0 4.5 0.6 11.1 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 GAN05225.1 - 3.9 7.6 11.1 0.52 10.4 6.4 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_C13 PF01650.18 GAN05226.1 - 1.1e-44 152.9 0.5 1.1e-44 152.9 0.5 1.3 2 0 0 2 2 2 1 Peptidase C13 family ArgoMid PF16487.5 GAN05226.1 - 0.0047 17.1 0.1 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 Mid domain of argonaute Benyvirus_14KDa PF07255.11 GAN05226.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Benyvirus 14KDa protein HIT PF01230.23 GAN05227.1 - 9.8e-19 67.9 1.0 3.2e-18 66.3 1.0 1.7 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAN05227.1 - 1.7e-08 35.0 0.7 4.7e-08 33.5 0.7 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAN05227.1 - 3e-05 23.9 1.0 6.1e-05 22.9 1.0 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SDH_alpha PF03313.15 GAN05228.1 - 7.7e-105 350.2 0.1 1.1e-104 349.8 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 GAN05228.1 - 1.1e-58 198.0 0.0 2.5e-58 196.9 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Imm42 PF15593.6 GAN05228.1 - 0.14 12.6 0.2 0.28 11.6 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 42 FAT PF02259.23 GAN05230.1 - 4.3e-71 239.9 10.5 4.3e-71 239.9 10.5 2.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 GAN05230.1 - 2.7e-29 102.7 3.1 3.2e-29 102.5 1.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAN05230.1 - 2e-05 24.3 0.9 5.4e-05 22.9 0.9 1.8 1 0 0 1 1 1 1 FATC domain DUF1160 PF06648.11 GAN05230.1 - 0.081 12.9 3.1 0.076 13.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) RasGEF_N_2 PF14663.6 GAN05230.1 - 0.33 11.4 4.9 6.3 7.2 0.1 4.8 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Nop14 PF04147.12 GAN05230.1 - 2.8 6.0 19.0 0.054 11.7 9.4 2.6 2 0 0 2 2 2 0 Nop14-like family Aldedh PF00171.22 GAN05232.1 - 1.1e-140 469.2 0.0 1.3e-140 469.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAN05232.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) M20_dimer PF07687.14 GAN05233.1 - 1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAN05233.1 - 2.8e-09 37.0 0.1 4.6e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HTH_1 PF00126.27 GAN05235.1 - 0.0048 16.8 0.1 0.0097 15.8 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 GAN05235.1 - 0.0055 16.2 0.1 0.038 13.6 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 GAN05235.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_32 PF13565.6 GAN05235.1 - 0.022 15.4 0.0 0.072 13.7 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_50 PF18024.1 GAN05235.1 - 0.039 13.5 0.0 0.095 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 GAN05235.1 - 0.049 13.3 0.4 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Mga PF05043.13 GAN05235.1 - 0.064 13.9 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_6 PF01418.17 GAN05235.1 - 0.12 12.4 0.2 0.35 10.9 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Stork_head PF10264.9 GAN05235.1 - 0.14 12.3 0.3 0.96 9.7 0.0 2.5 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain ABC2_membrane PF01061.24 GAN05236.1 - 1.2e-82 276.5 73.0 4.1e-46 157.1 22.9 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAN05236.1 - 1.4e-35 122.8 0.1 9.1e-18 65.1 0.0 3.3 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 GAN05236.1 - 1.6e-26 92.0 10.1 5.5e-19 67.9 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAN05236.1 - 3.1e-14 53.3 0.0 1.7e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAN05236.1 - 2.2e-11 43.5 37.7 9e-06 25.0 15.7 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 GAN05236.1 - 3e-06 27.7 0.0 0.017 15.5 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 GAN05236.1 - 3.8e-05 23.6 0.2 0.46 10.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAN05236.1 - 7.8e-05 22.6 0.5 0.0024 17.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 GAN05236.1 - 0.00024 21.6 0.0 0.055 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAN05236.1 - 0.00044 19.9 2.1 0.017 14.8 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAN05236.1 - 0.0013 18.4 0.0 0.03 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAN05236.1 - 0.0051 17.1 0.1 0.87 9.9 0.0 3.3 4 0 0 4 4 3 1 AAA domain FEZ PF07763.13 GAN05236.1 - 0.0073 16.1 0.5 0.014 15.1 0.5 1.4 1 0 0 1 1 1 1 FEZ-like protein DUF4294 PF14127.6 GAN05236.1 - 0.012 15.5 1.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) AAA_30 PF13604.6 GAN05236.1 - 0.028 14.2 0.2 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAN05236.1 - 0.034 13.7 0.3 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 GAN05236.1 - 0.043 14.2 0.0 18 5.7 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAN05236.1 - 0.065 13.3 0.7 9.9 6.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 GAN05236.1 - 0.08 12.9 1.2 5.1 7.0 0.2 2.8 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 GAN05236.1 - 0.12 11.5 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 GAN05236.1 - 0.12 12.5 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAN05236.1 - 0.19 11.6 0.0 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 GAN05236.1 - 0.25 11.3 1.1 3.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAN05236.1 - 7.2 6.8 5.6 1.2 9.4 0.2 2.4 3 0 0 3 3 2 0 AAA domain TFIIF_alpha PF05793.12 GAN05237.1 - 0.031 12.9 44.8 0.038 12.6 44.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF853 PF05872.12 GAN05237.1 - 2.7 6.5 5.6 3.5 6.1 5.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) BUD22 PF09073.10 GAN05237.1 - 9.3 5.5 60.2 20 4.4 60.2 1.5 1 1 0 1 1 1 0 BUD22 RXT2_N PF08595.11 GAN05238.1 - 0.0025 17.9 5.4 0.0031 17.6 5.4 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal ANAPC15 PF15243.6 GAN05238.1 - 0.014 15.8 7.6 0.021 15.2 7.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Neugrin PF06413.11 GAN05238.1 - 0.035 14.1 2.0 0.038 14.0 2.0 1.1 1 0 0 1 1 1 0 Neugrin Adenine_glyco PF03352.13 GAN05238.1 - 0.04 13.7 0.9 0.044 13.6 0.9 1.1 1 0 0 1 1 1 0 Methyladenine glycosylase Dicty_REP PF05086.12 GAN05238.1 - 0.041 11.9 4.3 0.042 11.9 4.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNA_pol_3_Rpc31 PF11705.8 GAN05238.1 - 0.068 13.4 6.8 0.075 13.3 6.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Saw1 PF11561.8 GAN05238.1 - 0.21 11.1 4.3 0.23 11.0 4.3 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Mpp10 PF04006.12 GAN05239.1 - 0.00085 17.9 15.9 0.001 17.6 15.9 1.1 1 0 0 1 1 1 1 Mpp10 protein CobT PF06213.12 GAN05239.1 - 0.0045 16.4 17.8 0.0059 16.0 17.8 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 GAN05239.1 - 0.038 13.3 19.2 0.045 13.1 19.2 1.0 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 GAN05239.1 - 0.04 13.1 23.4 0.051 12.7 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GAN05239.1 - 0.052 11.8 20.0 0.058 11.6 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 GAN05239.1 - 0.068 13.0 9.4 0.071 12.9 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 GAN05239.1 - 0.2 11.2 16.7 0.24 11.0 16.7 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 GAN05239.1 - 0.28 10.6 21.3 0.34 10.3 21.3 1.1 1 0 0 1 1 1 0 SDA1 DDHD PF02862.17 GAN05239.1 - 0.8 9.8 4.9 0.91 9.6 4.9 1.1 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 GAN05239.1 - 0.99 9.8 8.0 1.2 9.5 8.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 GAN05239.1 - 1.3 7.9 7.9 1.6 7.7 7.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Paf1 PF03985.13 GAN05239.1 - 1.4 7.8 24.2 1.7 7.6 24.2 1.1 1 0 0 1 1 1 0 Paf1 XRN_M PF17846.1 GAN05239.1 - 1.8 7.5 11.9 2.1 7.2 11.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain RPN2_C PF18004.1 GAN05239.1 - 1.9 8.4 14.3 2.8 7.8 14.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FYDLN_acid PF09538.10 GAN05239.1 - 2.6 8.8 19.4 4.5 8.0 19.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FGF-BP1 PF06473.12 GAN05239.1 - 5.2 6.8 7.7 6.3 6.6 7.7 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) TMEM119 PF15724.5 GAN05239.1 - 5.6 7.0 10.5 7.1 6.6 10.5 1.1 1 0 0 1 1 1 0 TMEM119 family SLC12 PF03522.15 GAN05239.1 - 5.6 5.9 7.2 6.7 5.6 7.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 GAN05239.1 - 7.3 4.7 19.5 7.5 4.7 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Tankyrase_bdg_C PF15327.6 GAN05239.1 - 8.8 6.8 12.5 12 6.3 12.5 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Pex14_N PF04695.13 GAN05239.1 - 9.1 6.9 9.9 14 6.3 9.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.7 GAN05239.1 - 9.1 4.3 11.6 11 4.0 11.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 GAN05239.1 - 9.8 4.8 13.7 12 4.5 13.7 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 GAN05239.1 - 9.9 4.1 29.4 13 3.7 29.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi PseudoU_synth_1 PF01416.20 GAN05240.1 - 9.5e-31 106.5 0.0 8.2e-28 97.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase FAM209 PF15206.6 GAN05241.1 - 0.1 12.4 1.2 0.37 10.6 0.5 2.1 3 0 0 3 3 3 0 FAM209 family Pirin PF02678.16 GAN05242.1 - 5.8e-32 109.9 0.1 1.1e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 GAN05242.1 - 1.6e-31 108.8 0.0 6.1e-30 103.7 0.1 2.5 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 GAN05242.1 - 0.039 13.7 2.5 0.05 13.3 0.8 2.0 2 0 0 2 2 2 0 Cupin domain Pirin_C_2 PF17954.1 GAN05242.1 - 0.18 12.0 0.0 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 Quercetinase C-terminal cupin domain DUF3576 PF12100.8 GAN05243.1 - 0.007 16.5 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3576) Septin PF00735.18 GAN05244.1 - 2.8e-122 407.4 0.3 3.2e-122 407.2 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN05244.1 - 6.4e-09 35.9 0.0 1.6e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN05244.1 - 3.3e-08 33.6 0.3 4.9e-06 26.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAN05244.1 - 2.1e-05 24.2 0.2 0.0032 17.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAN05244.1 - 7.1e-05 23.1 0.0 0.00058 20.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 GAN05244.1 - 0.00024 20.5 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 GAN05244.1 - 0.00033 21.2 0.1 0.00079 20.0 0.1 1.6 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 GAN05244.1 - 0.001 19.1 0.2 0.46 10.5 0.2 2.3 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 GAN05244.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN05244.1 - 0.0014 18.2 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.6 GAN05244.1 - 0.0044 17.4 0.0 0.0078 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAN05244.1 - 0.0055 16.4 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 GAN05244.1 - 0.0057 16.0 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 GAN05244.1 - 0.032 14.3 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAN05244.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAN05244.1 - 0.082 12.7 0.4 13 5.4 0.0 2.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 GAN05244.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 GAN05244.1 - 0.09 12.5 0.2 1.5 8.5 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 GAN05244.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 GAN05244.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GrpE PF01025.19 GAN05245.1 - 0.0025 17.5 4.9 0.0028 17.4 4.9 1.1 1 0 0 1 1 1 1 GrpE Atg14 PF10186.9 GAN05245.1 - 0.017 14.2 3.0 0.017 14.2 3.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 GAN05245.1 - 0.21 11.9 7.2 0.31 11.4 7.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 GAN05245.1 - 0.39 9.9 3.1 0.42 9.8 3.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF1090 PF06476.12 GAN05245.1 - 0.47 10.6 10.5 0.59 10.3 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DivIC PF04977.15 GAN05245.1 - 0.88 9.4 7.8 4.7 7.1 4.0 2.0 1 1 1 2 2 2 0 Septum formation initiator GPHR_N PF12537.8 GAN05245.1 - 2 8.6 3.4 4.5 7.4 0.3 2.1 1 1 1 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal MerR-DNA-bind PF09278.11 GAN05245.1 - 2.3 8.8 7.5 72 4.0 7.5 2.3 1 1 0 1 1 1 0 MerR, DNA binding TPX2 PF06886.11 GAN05245.1 - 4.4 7.6 15.6 0.43 10.9 9.4 2.0 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) TIM21 PF08294.11 GAN05246.1 - 5.2e-40 136.7 0.1 9e-40 135.9 0.1 1.4 1 0 0 1 1 1 1 TIM21 ArfGap PF01412.18 GAN05246.1 - 1.3e-29 102.6 0.1 1.3e-29 102.6 0.1 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Coa1 PF08695.10 GAN05246.1 - 0.00024 20.8 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Chs7 PF12271.8 GAN05247.1 - 4.9e-116 387.1 21.3 6e-116 386.8 21.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Nucleotid_trans PF03407.16 GAN05248.1 - 2.2e-24 86.7 0.7 2.9e-24 86.2 0.7 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase HA70_C PF17993.1 GAN05248.1 - 0.0023 18.0 0.1 0.013 15.5 0.0 2.1 2 1 1 3 3 3 1 Haemagglutinin 70 C-terminal domain G-alpha PF00503.20 GAN05250.1 - 4.5e-77 259.6 2.2 6.3e-77 259.1 2.2 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN05250.1 - 8.9e-13 48.1 3.2 1.8e-08 34.0 0.1 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 GAN05250.1 - 0.0041 17.3 0.2 1.6 8.9 0.0 2.6 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 GAN05250.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF685 PF05085.12 GAN05250.1 - 0.041 13.2 0.1 0.058 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF685) AAA_29 PF13555.6 GAN05250.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 GAN05250.1 - 0.087 12.2 2.4 3.6 6.9 0.0 2.7 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region BTG PF07742.12 GAN05251.1 - 3.1e-33 114.1 0.0 5.2e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 BTG family APG6_N PF17675.1 GAN05252.1 - 0.0058 17.2 6.3 0.013 16.0 6.3 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region CCDC144C PF14915.6 GAN05252.1 - 0.02 14.1 8.3 0.031 13.4 8.3 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Lebercilin PF15619.6 GAN05252.1 - 0.025 14.3 5.8 0.05 13.3 5.8 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease XhlA PF10779.9 GAN05252.1 - 0.12 12.6 6.6 0.039 14.2 2.7 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Laminin_II PF06009.12 GAN05252.1 - 0.18 11.8 2.3 0.5 10.4 2.3 1.7 1 0 0 1 1 1 0 Laminin Domain II DMPK_coil PF08826.10 GAN05252.1 - 0.67 10.1 3.4 1.1 9.4 2.3 1.9 1 1 0 1 1 1 0 DMPK coiled coil domain like CCDC53 PF10152.9 GAN05252.1 - 0.71 10.3 0.0 0.71 10.3 0.0 3.7 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex MFS_2 PF13347.6 GAN05253.1 - 1.7e-07 30.2 6.6 1.7e-07 30.2 6.6 2.7 3 1 0 3 3 3 2 MFS/sugar transport protein DUF962 PF06127.11 GAN05253.1 - 0.018 15.1 7.5 0.64 10.1 0.9 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF962) TMEM132D_C PF15706.5 GAN05253.1 - 7.8 6.4 5.4 1.3 8.8 0.2 2.4 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Methyltransf_25 PF13649.6 GAN05254.1 - 7.1e-15 55.5 0.0 1.7e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05254.1 - 9.7e-13 48.3 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05254.1 - 1.5e-12 48.0 0.0 3.9e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN05254.1 - 6.3e-10 39.7 0.0 1.9e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN05254.1 - 1.9e-08 34.3 0.0 6.8e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05254.1 - 4.1e-08 32.8 0.0 8.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN05254.1 - 2.4e-05 23.9 0.0 0.00038 20.0 0.0 2.5 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 GAN05254.1 - 7.5e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 GAN05254.1 - 0.00049 20.3 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.18 GAN05254.1 - 0.0057 16.2 0.1 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain MetW PF07021.12 GAN05254.1 - 0.049 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 GAN05254.1 - 0.056 12.0 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 GAN05254.1 - 0.078 12.3 0.0 0.16 11.2 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 GAN05254.1 - 0.14 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FMN_dh PF01070.18 GAN05255.1 - 0.052 12.6 0.0 0.06 12.4 0.0 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHH PF01368.20 GAN05255.1 - 0.59 10.4 2.6 3.9 7.8 0.2 2.2 1 1 1 2 2 2 0 DHH family NTNH_C PF08470.10 GAN05256.1 - 0.0039 17.1 1.7 0.0063 16.4 1.7 1.3 1 0 0 1 1 1 1 Nontoxic nonhaemagglutinin C-terminal DAD PF02109.16 GAN05257.1 - 7.2e-44 148.6 2.0 7.9e-44 148.4 2.0 1.0 1 0 0 1 1 1 1 DAD family TFIIF_beta PF02270.15 GAN05258.1 - 1.8e-26 92.0 0.0 2.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 GAN05258.1 - 7.1e-24 85.0 0.3 3.1e-23 83.0 0.3 2.1 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 GAN05258.1 - 0.0014 19.5 0.1 0.0022 18.8 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PLDc_3 PF13918.6 GAN05258.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PLD-like domain PH PF00169.29 GAN05259.1 - 0.027 15.0 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 PH domain Bep_C_terminal PF17841.1 GAN05259.1 - 0.29 11.4 3.3 0.39 11.0 0.3 2.4 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) LpoB PF13036.6 GAN05259.1 - 1.4 8.9 7.5 0.12 12.3 0.5 2.6 2 1 1 3 3 3 0 Peptidoglycan-synthase activator LpoB BSP_II PF05432.11 GAN05259.1 - 2.3 7.8 8.8 4.8 6.8 8.8 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Glyco_hydro_16 PF00722.21 GAN05260.1 - 4.2e-30 104.5 0.9 5.8e-30 104.1 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 QCR10 PF09796.9 GAN05261.1 - 1.1e-17 63.9 0.0 1.3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF2064 PF09837.9 GAN05261.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) RhoGAP PF00620.27 GAN05262.1 - 3.4e-25 88.7 0.1 9.8e-25 87.2 0.1 1.8 1 1 1 2 2 2 1 RhoGAP domain VHS PF00790.19 GAN05263.1 - 4.6e-19 68.7 0.1 9.7e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAN05263.1 - 5.9e-07 29.7 2.2 6.6e-07 29.6 0.2 2.2 2 0 0 2 2 2 1 GAT domain MMR_HSR1 PF01926.23 GAN05264.1 - 3.2e-15 56.2 0.0 1.7e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN05264.1 - 8.8e-06 25.7 0.1 0.00052 20.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAN05264.1 - 0.00043 19.8 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 GAN05264.1 - 0.0079 15.5 0.2 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 GAN05264.1 - 0.01 15.9 2.2 0.045 13.8 0.1 3.0 3 1 1 4 4 4 0 Dynamin family Roc PF08477.13 GAN05264.1 - 0.014 15.6 0.2 0.1 12.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 GAN05264.1 - 0.022 14.5 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 GAN05264.1 - 0.028 13.9 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 GAN05264.1 - 0.1 11.9 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Septin HD_3 PF13023.6 GAN05265.1 - 7.5e-47 159.3 0.4 9.2e-47 159.0 0.4 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 GAN05265.1 - 4.4e-11 42.9 0.3 6.2e-11 42.4 0.3 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 GAN05265.1 - 3.7e-06 27.2 0.4 6.9e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 HD domain SapC PF07277.11 GAN05265.1 - 0.067 12.8 0.2 0.091 12.3 0.2 1.2 1 0 0 1 1 1 0 SapC Pkinase PF00069.25 GAN05266.1 - 1.4e-57 195.1 2.3 1.4e-55 188.5 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05266.1 - 6e-27 94.5 0.3 1.3e-25 90.1 0.0 2.7 2 1 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05266.1 - 3.3e-11 43.0 0.0 5.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN05266.1 - 0.00073 18.6 0.2 0.00073 18.6 0.2 2.7 3 0 0 3 3 3 1 Haspin like kinase domain Kdo PF06293.14 GAN05266.1 - 0.016 14.6 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN05266.1 - 0.022 14.7 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAN05266.1 - 0.099 12.2 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HELP PF03451.14 GAN05267.1 - 0.048 13.5 2.1 0.41 10.5 0.4 2.2 2 0 0 2 2 2 0 HELP motif PIP5K PF01504.18 GAN05268.1 - 6.7e-30 104.2 7.1 4e-28 98.4 4.7 2.8 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PRIMA1 PF16101.5 GAN05268.1 - 4.5 7.3 14.6 1.4 9.0 0.5 3.2 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 RasGEF PF00617.19 GAN05269.1 - 1.8e-59 200.9 0.7 5e-59 199.5 0.7 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN05269.1 - 6.3e-27 93.9 0.8 3.2e-26 91.6 0.8 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 GAN05269.1 - 1.3e-13 50.3 0.2 3e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN05269.1 - 1.6e-11 43.9 0.1 3.1e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN05269.1 - 5.6e-10 38.8 0.1 1.1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 GAN05269.1 - 1.9e-06 27.8 8.3 0.00017 21.6 4.3 2.7 2 0 0 2 2 2 2 WW domain p450 PF00067.22 GAN05270.1 - 3.7e-81 273.2 0.0 4.5e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3177 PF11375.8 GAN05270.1 - 0.12 12.2 0.5 1.1 9.0 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3177) RRM_1 PF00076.22 GAN05271.1 - 3e-27 94.3 0.5 1e-09 38.1 0.3 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN05271.1 - 5.7e-11 42.1 0.2 0.025 14.4 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif NID PF07292.13 GAN05271.1 - 0.00021 21.9 0.0 0.03 15.0 0.0 3.5 4 0 0 4 4 4 1 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 GAN05271.1 - 0.00047 20.2 0.0 0.65 10.2 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 GAN05271.1 - 0.0048 16.9 0.5 0.23 11.5 0.2 2.9 3 1 0 3 3 3 1 RNA binding motif DUF4523 PF15023.6 GAN05271.1 - 0.0049 16.7 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) RRM_5 PF13893.6 GAN05271.1 - 0.038 13.6 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN05271.1 - 0.06 13.4 0.1 24 5.0 0.0 3.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 GAN05271.1 - 0.071 12.8 0.2 2.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Innate_immun PF12782.7 GAN05271.1 - 0.47 9.9 4.0 0.74 9.3 4.0 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family WD40 PF00400.32 GAN05272.1 - 4.8e-19 68.3 0.3 7e-06 26.7 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAN05272.1 - 0.014 14.4 0.0 4.3 6.2 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAN05272.1 - 0.1 11.2 1.3 0.13 10.9 0.3 1.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 GAN05272.1 - 0.19 12.3 0.6 13 6.4 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain GCFC PF07842.12 GAN05273.1 - 1.2e-73 248.1 21.6 2.3e-73 247.2 21.6 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 GAN05273.1 - 5.6e-14 51.8 2.1 1.3e-13 50.6 2.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN05273.1 - 1.3e-06 28.4 1.6 1.3e-06 28.4 1.6 2.2 2 0 0 2 2 2 1 G-patch domain AAA_23 PF13476.6 GAN05273.1 - 0.2 12.1 8.1 0.41 11.1 8.1 1.5 1 0 0 1 1 1 0 AAA domain CCDC-167 PF15188.6 GAN05273.1 - 0.43 11.0 3.2 2 8.8 3.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 CDC45 PF02724.14 GAN05274.1 - 4.7e-197 656.2 8.1 4.8e-196 652.9 8.1 1.9 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 GAN05274.1 - 0.037 13.4 0.8 0.052 12.9 0.8 1.1 1 0 0 1 1 1 0 BUD22 MAF_flag10 PF01973.18 GAN05274.1 - 0.11 12.2 0.2 0.3 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF115 Glyco_transf_10 PF00852.19 GAN05275.1 - 1.5e-40 138.8 0.5 2.1e-40 138.3 0.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_trans_1_2 PF13524.6 GAN05275.1 - 0.014 15.8 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 EphA2_TM PF14575.6 GAN05275.1 - 0.25 12.3 1.1 35 5.4 0.1 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TPT PF03151.16 GAN05276.1 - 9.2e-06 25.2 9.4 1.3e-05 24.7 9.4 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN05276.1 - 1.7e-05 25.0 29.5 0.00079 19.6 3.5 2.6 3 0 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 GAN05276.1 - 0.0081 15.1 11.8 0.0061 15.6 4.0 2.3 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like NifU_N PF01592.16 GAN05277.1 - 2.3e-54 183.0 0.2 2.7e-54 182.7 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L35Ae PF01247.18 GAN05278.1 - 1.7e-42 143.5 0.9 1.9e-42 143.3 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAN05278.1 - 0.0014 18.8 0.1 0.28 11.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Bcr-Abl_Oligo PF09036.10 GAN05278.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain zf-H2C2_2 PF13465.6 GAN05279.1 - 1.7e-12 47.2 5.6 0.00011 22.5 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 GAN05279.1 - 1e-09 38.3 7.7 0.00045 20.5 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN05279.1 - 8.4e-07 29.3 7.8 0.014 16.2 1.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 GAN05279.1 - 0.00061 20.1 2.3 0.0013 19.0 0.2 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 GAN05279.1 - 0.0028 17.5 2.5 0.64 10.0 0.7 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 GAN05279.1 - 0.006 16.6 0.9 0.006 16.6 0.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAN05279.1 - 0.049 13.9 5.5 0.12 12.7 0.5 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-HC5HC2H PF13771.6 GAN05279.1 - 0.078 13.2 2.1 0.24 11.7 2.1 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain FOXP-CC PF16159.5 GAN05279.1 - 0.1 13.3 0.5 3.7 8.3 0.0 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain MCM_OB PF17207.3 GAN05279.1 - 0.16 11.8 1.4 0.31 10.9 1.4 1.5 1 0 0 1 1 1 0 MCM OB domain zf-C2H2_11 PF16622.5 GAN05279.1 - 0.25 11.2 6.5 0.43 10.4 0.6 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type MFS_1_like PF12832.7 GAN05280.1 - 1.1e-61 208.9 18.6 1.4e-61 208.5 18.6 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAN05280.1 - 2.9e-16 59.4 44.7 1.2e-06 27.8 10.7 3.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAN05280.1 - 7.5e-10 38.4 8.3 7.5e-10 38.4 8.3 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter Pkinase PF00069.25 GAN05281.1 - 7.1e-60 202.6 0.1 1.6e-58 198.2 0.1 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05281.1 - 1.3e-26 93.5 0.8 3.6e-23 82.2 0.2 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN05281.1 - 0.0048 15.9 0.2 0.0098 14.9 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN05281.1 - 0.0054 16.1 0.1 0.0099 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN05281.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family GLF PF03275.13 GAN05281.1 - 0.083 12.6 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 UDP-galactopyranose mutase HMGL-like PF00682.19 GAN05282.1 - 4e-97 324.9 0.1 6.8e-97 324.1 0.1 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 GAN05282.1 - 8.3e-21 74.3 5.5 1.5e-20 73.4 5.5 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Actin PF00022.19 GAN05283.1 - 2.5e-143 477.6 0.0 3.1e-143 477.3 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAN05283.1 - 6.2e-06 25.3 0.0 0.01 14.7 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein CPSF100_C PF13299.6 GAN05283.1 - 0.0001 22.5 1.4 0.26 11.5 0.5 2.3 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal DUF1644 PF07800.12 GAN05283.1 - 0.11 12.5 1.1 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) RNA_pol_Rpc4 PF05132.14 GAN05283.1 - 0.26 11.7 8.9 0.5 10.8 4.4 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Cytomega_UL84 PF06284.11 GAN05283.1 - 0.4 9.1 1.8 0.6 8.5 1.8 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Presenilin PF01080.17 GAN05283.1 - 1.5 7.5 4.1 0.59 8.8 1.2 1.7 2 0 0 2 2 2 0 Presenilin HSF_DNA-bind PF00447.17 GAN05284.1 - 1.2e-29 102.7 6.1 1.2e-29 102.7 6.1 3.0 3 0 0 3 3 3 1 HSF-type DNA-binding Response_reg PF00072.24 GAN05284.1 - 5.6e-27 94.1 0.4 2e-26 92.3 0.4 2.0 1 0 0 1 1 1 1 Response regulator receiver domain MRF_C1 PF13887.6 GAN05284.1 - 0.11 11.7 0.0 0.31 10.2 0.0 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Macoilin PF09726.9 GAN05284.1 - 0.11 11.0 38.7 0.1 11.1 7.3 3.1 3 0 0 3 3 3 0 Macoilin family M-inducer_phosp PF06617.13 GAN05285.1 - 0.025 13.9 0.2 0.048 12.9 0.2 1.4 1 0 0 1 1 1 0 M-phase inducer phosphatase Stealth_CR4 PF17103.5 GAN05285.1 - 0.062 13.2 0.5 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 DDE_3 PF13358.6 GAN05286.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_16 PF13191.6 GAN05287.1 - 0.0035 17.8 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Guanylate_cyc PF00211.20 GAN05287.1 - 0.011 15.4 0.0 6.7 6.3 0.0 3.4 3 0 0 3 3 3 0 Adenylate and Guanylate cyclase catalytic domain AA_permease PF00324.21 GAN05288.1 - 1.6e-124 416.1 42.0 2e-124 415.8 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN05288.1 - 1.3e-35 123.0 44.0 1.7e-35 122.7 44.0 1.1 1 0 0 1 1 1 1 Amino acid permease Rad21_Rec8_N PF04825.13 GAN05289.1 - 2.7e-33 114.4 0.1 4.8e-33 113.6 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAN05289.1 - 2.3e-14 52.4 0.0 7e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 GAN05289.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Na_Ca_ex PF01699.24 GAN05290.1 - 1.5e-43 148.3 48.8 3.8e-23 82.1 19.7 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein CrgA PF06781.12 GAN05290.1 - 0.0094 16.0 0.4 0.059 13.4 0.0 2.6 2 0 0 2 2 2 1 Cell division protein CrgA DUF4366 PF14283.6 GAN05290.1 - 0.016 15.3 0.1 0.28 11.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Inhibitor_I9 PF05922.16 GAN05290.1 - 0.027 15.1 0.0 0.058 14.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF5383 PF17355.2 GAN05290.1 - 0.052 13.9 3.7 0.093 13.1 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Peptidase_C37 PF05416.12 GAN05290.1 - 0.19 10.2 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF2207 PF09972.9 GAN05290.1 - 1.2 7.8 0.0 1.2 7.8 0.0 3.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) G-alpha PF00503.20 GAN05291.1 - 1.1e-123 412.9 3.9 1.2e-123 412.8 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN05291.1 - 2.7e-16 59.5 1.2 1.2e-10 41.1 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN05291.1 - 0.00016 21.1 2.3 0.013 14.8 0.1 2.5 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAN05291.1 - 0.003 17.8 0.0 0.53 10.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAN05291.1 - 0.059 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GAN05291.1 - 0.082 12.2 0.1 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family zf-Di19 PF05605.12 GAN05292.1 - 0.0028 17.9 0.3 0.86 9.9 0.0 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 GAN05292.1 - 0.0047 16.8 0.3 3.5 7.6 0.1 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 DUF1644 PF07800.12 GAN05292.1 - 0.013 15.6 1.0 1.3 9.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) Zn-C2H2_12 PF18112.1 GAN05292.1 - 0.013 15.9 2.0 0.82 10.2 0.2 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_2 PF13639.6 GAN05292.1 - 0.097 13.0 2.0 3.8 7.9 0.5 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 GAN05292.1 - 0.2 11.7 2.8 2.2 8.4 0.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger DUF4203 PF13886.6 GAN05293.1 - 5.4e-35 120.9 32.8 5.4e-35 120.9 32.8 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) DUF4834 PF16118.5 GAN05293.1 - 0.0097 16.9 1.5 1.2 10.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) DUF2227 PF09988.9 GAN05293.1 - 0.12 12.3 2.5 7.6 6.4 0.5 2.8 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) DUF3332 PF11810.8 GAN05293.1 - 3.2 7.4 4.1 16 5.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3332) Presenilin PF01080.17 GAN05293.1 - 6.5 5.4 9.5 15 4.2 6.3 2.7 3 0 0 3 3 3 0 Presenilin HMA PF00403.26 GAN05294.1 - 1.2e-78 259.5 5.7 9.3e-13 48.4 0.0 7.7 7 0 0 7 7 7 7 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 GAN05294.1 - 2.1e-49 167.5 1.4 2.1e-49 167.5 1.4 3.1 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAN05294.1 - 2.3e-32 113.0 1.1 1e-31 110.9 1.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN05294.1 - 0.00018 21.4 0.4 0.0025 17.6 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Poly_export PF02563.16 GAN05294.1 - 0.0012 19.0 0.2 17 5.7 0.0 4.9 6 0 0 6 6 6 1 Polysaccharide biosynthesis/export protein HAD PF12710.7 GAN05294.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAN05294.1 - 0.054 13.6 0.2 17 5.6 0.0 4.4 4 1 0 4 4 4 0 Haloacid dehalogenase-like hydrolase Gmx_para_CXXCG PF09535.10 GAN05294.1 - 0.056 12.7 0.6 1e+02 2.1 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (Gmx_para_CXXCG) DUF2200 PF09966.9 GAN05294.1 - 0.72 10.0 4.9 25 5.1 0.0 5.1 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2200) TusA PF01206.17 GAN05294.1 - 1.2 9.1 4.5 35 4.3 0.0 5.3 6 0 0 6 6 6 0 Sulfurtransferase TusA F-box-like PF12937.7 GAN05295.1 - 2.1e-05 24.3 0.7 5.8e-05 22.9 0.7 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN05295.1 - 0.053 14.0 22.1 5.2 7.6 5.7 6.5 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) Xpo1 PF08389.12 GAN05297.1 - 1.8e-15 57.3 1.5 1.4e-13 51.2 0.1 3.7 3 0 0 3 3 3 1 Exportin 1-like protein Importin_rep PF18773.1 GAN05297.1 - 7.7e-11 41.5 0.3 2.1e-10 40.2 0.3 1.8 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 GAN05297.1 - 4.6e-09 36.1 1.0 1.7e-08 34.3 1.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 GAN05297.1 - 7e-08 32.4 0.0 7.6e-07 29.1 0.0 2.6 2 0 0 2 2 2 1 Importin 13 repeat CRM1_C PF08767.11 GAN05297.1 - 0.01 15.0 0.2 0.028 13.6 0.2 1.7 1 0 0 1 1 1 0 CRM1 C terminal Mod_r PF07200.13 GAN05297.1 - 2.3 8.3 4.7 0.42 10.7 0.3 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Acetyltransf_1 PF00583.25 GAN05298.1 - 3.5e-15 56.2 0.0 4.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN05298.1 - 4.3e-09 36.4 0.1 5.3e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN05298.1 - 1.6e-07 31.6 0.0 2.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN05298.1 - 4.1e-06 26.7 0.0 6.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAN05298.1 - 0.00039 20.5 0.3 0.00054 20.1 0.3 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAN05298.1 - 0.015 14.8 0.9 0.054 13.0 0.2 2.2 1 1 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 GAN05298.1 - 0.031 14.9 0.0 0.043 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EnY2 PF10163.9 GAN05299.1 - 9.8e-24 83.5 0.1 1.1e-23 83.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Synapsin_N PF10581.9 GAN05299.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Synapsin N-terminal PIF1 PF05970.14 GAN05300.1 - 1.2e-07 31.2 0.1 0.00034 19.9 0.0 2.0 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GAN05300.1 - 0.00023 20.9 0.0 0.0003 20.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN05300.1 - 0.0014 19.1 0.0 0.0014 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 GAN05300.1 - 0.0022 17.0 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain PhoH PF02562.16 GAN05300.1 - 0.02 14.4 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 GAN05300.1 - 0.056 12.7 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GAN05300.1 - 0.062 13.3 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2791 PF10923.8 GAN05300.1 - 0.074 11.9 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_15 PF13175.6 GAN05300.1 - 0.083 12.6 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GAN05300.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region CbiA PF01656.23 GAN05300.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD_C_2 PF13538.6 GAN05301.1 - 0.039 13.8 0.3 0.3 10.9 0.3 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 GAN05301.1 - 0.069 11.1 0.0 0.079 10.9 0.0 1.1 1 0 0 1 1 1 0 Helicase OTU PF02338.19 GAN05304.1 - 0.057 13.9 0.0 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 OTU-like cysteine protease Plus-3 PF03126.18 GAN05305.1 - 5.6e-36 123.4 0.5 1.6e-35 121.9 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain ADP_PFK_GK PF04587.15 GAN05305.1 - 0.034 12.7 7.4 0.052 12.1 7.0 1.4 1 1 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region RskA PF10099.9 GAN05305.1 - 0.53 10.6 11.1 1.5 9.1 11.1 1.7 1 0 0 1 1 1 0 Anti-sigma-K factor rskA K_channel_TID PF07941.11 GAN05305.1 - 0.7 10.4 11.8 2.1 8.8 11.8 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain YEATS PF03366.16 GAN05306.1 - 5.8e-17 61.4 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 YEATS family RabGAP-TBC PF00566.18 GAN05307.1 - 5.9e-57 192.8 0.1 5.9e-57 192.8 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TSC22 PF01166.18 GAN05307.1 - 0.15 12.4 5.2 0.87 9.9 2.6 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family TMPIT PF07851.13 GAN05307.1 - 0.64 9.2 7.5 1.4 8.1 7.5 1.5 1 0 0 1 1 1 0 TMPIT-like protein Occludin_ELL PF07303.13 GAN05307.1 - 2 9.2 10.5 0.47 11.2 0.2 3.8 3 1 1 4 4 4 0 Occludin homology domain GAS PF13851.6 GAN05307.1 - 3 7.1 13.3 38 3.6 0.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Peptidase_S8 PF00082.22 GAN05308.1 - 3.3e-32 112.0 0.9 1.7e-27 96.5 0.4 2.4 2 0 0 2 2 2 2 Subtilase family fn3_5 PF06280.12 GAN05308.1 - 1.3e-09 38.7 0.7 2.4e-09 37.9 0.7 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 GAN05308.1 - 1.4e-08 34.6 0.4 1.7e-07 31.2 0.0 2.7 3 0 0 3 3 3 1 PA domain Peptidase_S8 PF00082.22 GAN05309.1 - 2.8e-49 168.0 0.4 4.2e-49 167.4 0.4 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 GAN05309.1 - 1e-10 41.5 0.0 3e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 PA domain fn3_5 PF06280.12 GAN05309.1 - 4.8e-10 40.1 0.0 1.1e-09 39.0 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain DUF4232 PF14016.6 GAN05309.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) HSP70 PF00012.20 GAN05310.1 - 1.1e-05 23.9 1.0 0.0019 16.5 0.0 3.0 4 0 0 4 4 4 2 Hsp70 protein ComGG PF14173.6 GAN05311.1 - 0.031 14.7 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 0 ComG operon protein 7 SLM4 PF16818.5 GAN05311.1 - 0.09 12.7 3.7 0.25 11.3 3.7 1.7 1 0 0 1 1 1 0 Protein SLM4 SMC_Nse1 PF07574.13 GAN05314.1 - 7.1e-23 81.5 7.8 1.2e-22 80.8 1.8 2.8 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex Homeodomain PF00046.29 GAN05314.1 - 3.3e-18 65.3 1.3 3.3e-18 65.3 1.3 2.2 2 0 0 2 2 2 1 Homeodomain zf-RING-like PF08746.11 GAN05314.1 - 1.1e-09 38.4 9.6 2.3e-09 37.4 9.6 1.6 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 GAN05314.1 - 0.0039 17.5 9.1 0.0082 16.5 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.6 GAN05314.1 - 0.0091 16.1 0.8 0.023 14.9 0.8 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain RskA PF10099.9 GAN05314.1 - 0.02 15.2 0.9 0.02 15.2 0.9 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA YdaS_antitoxin PF15943.5 GAN05314.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PHD_2 PF13831.6 GAN05314.1 - 2 8.0 4.9 4.1 7.1 4.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-CCHC_2 PF13696.6 GAN05315.1 - 4.6e-09 35.9 8.1 4.6e-09 35.9 8.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 GAN05315.1 - 1.6e-05 24.8 3.0 1.6e-05 24.8 3.0 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 GAN05315.1 - 0.00093 19.0 9.7 0.00093 19.0 9.7 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 GAN05315.1 - 0.0037 17.2 1.3 0.0037 17.2 1.3 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_3 PF13920.6 GAN05315.1 - 0.0071 16.2 10.1 0.0071 16.2 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN05315.1 - 0.015 15.2 11.0 0.015 15.2 11.0 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 GAN05315.1 - 0.022 14.5 0.1 0.062 13.0 0.1 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-RING_UBOX PF13445.6 GAN05315.1 - 0.027 14.5 7.6 0.095 12.7 7.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 GAN05315.1 - 0.036 14.4 10.8 0.036 14.4 10.8 2.2 3 0 0 3 3 2 0 Ring finger domain zf-RING_6 PF14835.6 GAN05315.1 - 0.13 12.1 4.6 0.27 11.1 4.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 GAN05315.1 - 0.15 12.3 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 U-box domain zf-H2C2_2 PF13465.6 GAN05315.1 - 1.9 9.0 5.4 21 5.8 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C3HC4_4 PF15227.6 GAN05315.1 - 2.6 8.3 17.0 0.088 13.0 10.6 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GAN05315.1 - 6.2 6.9 20.1 1.8 8.6 13.2 2.8 2 1 1 3 3 3 0 zinc-RING finger domain DWNN PF08783.11 GAN05316.1 - 3e-24 85.1 0.3 1e-23 83.4 0.3 1.8 1 1 0 1 1 1 1 DWNN domain Hydrolase PF00702.26 GAN05317.1 - 7.5e-09 36.2 0.1 1e-08 35.8 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN05317.1 - 0.021 14.9 0.1 0.035 14.2 0.1 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RT_RNaseH PF17917.1 GAN05320.1 - 2.4e-30 104.9 0.8 6.5e-30 103.5 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN05320.1 - 1.6e-29 101.9 0.2 6.3e-29 100.0 0.2 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GAN05320.1 - 3.9e-18 65.8 0.0 9.4e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GAN05320.1 - 2.5e-14 53.1 0.7 5.3e-14 52.1 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GAN05320.1 - 1.2e-06 28.2 0.2 3.5e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_3 PF13456.6 GAN05320.1 - 0.00057 19.7 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like zf-H2C2 PF09337.10 GAN05320.1 - 0.0076 16.5 0.1 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger PYRIN PF02758.16 GAN05320.1 - 0.14 12.3 1.8 5.7 7.2 0.2 3.4 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain La PF05383.17 GAN05321.1 - 4.3e-06 26.7 0.0 9.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 La domain PPP5 PF08321.12 GAN05322.1 - 5.3e-31 106.8 4.2 6.6e-31 106.5 1.1 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 GAN05322.1 - 3.6e-30 106.0 0.4 5.4e-30 105.4 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 GAN05322.1 - 1.4e-14 53.2 4.7 0.00079 19.1 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN05322.1 - 1.2e-10 40.6 7.5 0.011 15.8 0.0 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN05322.1 - 2.5e-09 36.7 0.2 0.0001 21.9 0.0 2.9 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 GAN05322.1 - 3.8e-05 23.6 2.2 0.65 10.3 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN05322.1 - 5e-05 23.4 0.0 0.00061 19.9 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN05322.1 - 0.0002 21.5 4.5 0.23 11.9 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN05322.1 - 0.00024 21.4 0.3 0.21 11.9 0.0 3.2 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAN05322.1 - 0.00074 20.0 0.2 0.0079 16.7 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN05322.1 - 0.0017 19.0 0.0 0.018 15.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN05322.1 - 0.0057 17.3 0.1 3.5 8.3 0.1 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAN05322.1 - 0.0074 15.7 0.0 10 5.7 0.0 3.1 3 0 0 3 3 3 1 SHNi-TPR Fis1_TPR_C PF14853.6 GAN05322.1 - 0.15 12.2 0.1 9.3 6.4 0.0 2.7 2 1 1 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 GAN05322.1 - 0.18 11.9 3.9 2.1 8.5 0.6 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain HsbA PF12296.8 GAN05324.1 - 9.7e-10 38.9 1.6 9.7e-10 38.9 1.6 1.8 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1640 PF07798.11 GAN05325.1 - 1.2e-47 162.2 7.8 1.2e-47 162.2 7.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Peptidase_M56 PF05569.11 GAN05325.1 - 0.007 15.6 0.1 0.016 14.4 0.1 1.6 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4407 PF14362.6 GAN05325.1 - 0.027 13.8 3.1 0.04 13.3 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG13 PF10033.9 GAN05325.1 - 0.33 10.6 3.8 0.16 11.6 0.5 1.9 2 0 0 2 2 2 0 Autophagy-related protein 13 STIMATE PF12400.8 GAN05326.1 - 4.8e-40 137.0 11.1 7.5e-40 136.4 11.1 1.3 1 0 0 1 1 1 1 STIMATE family SGL PF08450.12 GAN05327.1 - 0.0019 17.9 0.0 0.0046 16.6 0.0 1.6 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 GAN05327.1 - 0.019 15.3 0.0 7.9 6.9 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN05327.1 - 0.035 15.0 3.9 25 6.0 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 GAN05328.1 - 1.1e-17 64.1 13.2 0.00042 21.1 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05328.1 - 6.5e-09 36.0 1.6 0.00017 21.8 0.5 4.3 2 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN05328.1 - 6.6e-08 31.7 0.4 7.9e-07 28.1 0.3 2.4 3 0 0 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAN05328.1 - 0.011 15.8 0.0 1.3 9.1 0.0 3.4 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1513 PF07433.11 GAN05328.1 - 0.049 12.7 0.6 0.12 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Frankia_peptide PF14407.6 GAN05328.1 - 0.056 13.4 1.6 0.26 11.3 0.4 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Hira PF07569.11 GAN05328.1 - 0.09 12.5 0.1 11 5.6 0.1 3.0 2 1 1 3 3 3 0 TUP1-like enhancer of split Kinesin PF00225.23 GAN05330.1 - 1.4e-105 353.0 0.2 1.4e-105 353.0 0.2 2.7 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAN05330.1 - 1.2e-23 83.7 0.0 5.4e-23 81.6 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF1400 PF07176.11 GAN05330.1 - 0.009 16.3 0.6 0.1 12.9 0.1 3.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1400) Pox_A_type_inc PF04508.12 GAN05330.1 - 0.043 13.7 0.9 31 4.7 0.1 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlxA PF14282.6 GAN05330.1 - 0.096 12.7 0.1 0.096 12.7 0.1 9.2 8 2 3 11 11 11 0 FlxA-like protein ANAPC4 PF12896.7 GAN05331.1 - 2.5e-33 115.3 2.7 4.4e-33 114.5 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 GAN05331.1 - 6.2e-11 42.5 0.1 1.8e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PLDc PF00614.22 GAN05332.1 - 4.6e-11 42.4 0.1 2e-10 40.4 0.1 2.2 1 0 0 1 1 1 1 Phospholipase D Active site motif PX PF00787.24 GAN05332.1 - 7.2e-08 32.4 0.1 3.3e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 PX domain PLDc_2 PF13091.6 GAN05332.1 - 3.9e-07 30.0 0.1 0.00019 21.4 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain ArfGap PF01412.18 GAN05333.1 - 3.6e-34 117.3 1.9 5.1e-34 116.9 1.9 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3973 PF13119.6 GAN05333.1 - 0.043 13.9 0.1 1 9.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) CoA_transf_3 PF02515.17 GAN05334.1 - 6.8e-70 236.0 0.0 2.3e-69 234.3 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III Nuf2 PF03800.14 GAN05335.1 - 5.4e-18 65.4 0.4 5.4e-18 65.4 0.4 2.3 2 1 0 2 2 2 1 Nuf2 family Seryl_tRNA_N PF02403.22 GAN05335.1 - 0.0087 16.3 6.5 0.0087 16.3 6.5 4.7 4 1 1 5 5 5 1 Seryl-tRNA synthetase N-terminal domain DUF2431 PF10354.9 GAN05335.1 - 6.1 7.1 9.4 59 3.9 9.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2431) Kelch_5 PF13854.6 GAN05336.1 - 1.7e-25 88.5 5.3 2.1e-06 27.5 0.0 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 GAN05336.1 - 2.1e-22 78.2 10.1 3.2e-07 30.0 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GAN05336.1 - 7.5e-22 76.6 4.9 6.8e-06 25.6 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAN05336.1 - 1.2e-20 73.2 5.2 3.2e-07 30.2 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN05336.1 - 1.7e-19 69.6 7.2 0.00013 22.1 0.0 6.0 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN05336.1 - 1.6e-17 63.1 8.1 0.00051 20.2 0.1 5.8 6 0 0 6 6 6 4 Kelch motif BTB PF00651.31 GAN05336.1 - 8.6e-16 58.2 0.3 3.5e-15 56.2 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.25 GAN05337.1 - 3.4e-71 239.7 0.2 3.4e-71 239.7 0.2 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05337.1 - 1.2e-49 169.0 0.2 1.2e-49 169.0 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 GAN05337.1 - 1.3e-21 76.6 0.0 3.3e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 GAN05337.1 - 3.1e-14 53.3 0.5 1.1e-13 51.6 0.5 2.0 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 GAN05337.1 - 3.9e-06 26.4 0.0 1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN05337.1 - 0.00011 21.3 2.0 0.00023 20.2 1.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAN05337.1 - 0.00038 19.4 16.5 0.0018 17.1 16.3 2.0 1 1 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 GAN05337.1 - 0.0005 20.5 0.2 0.15 12.5 0.2 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAN05337.1 - 0.029 14.8 0.1 4.8 7.6 0.0 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain APH PF01636.23 GAN05337.1 - 0.74 9.7 5.9 0.25 11.2 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF724 PF05266.14 GAN05337.1 - 2.2 8.1 13.0 4 7.2 10.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HsbA PF12296.8 GAN05338.1 - 3.5e-12 46.8 1.5 4.2e-12 46.6 1.5 1.0 1 0 0 1 1 1 1 Hydrophobic surface binding protein A VWA_3 PF13768.6 GAN05338.1 - 0.042 13.8 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain NCBP3 PF10309.9 GAN05340.1 - 5.5e-17 61.4 0.0 9e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 GAN05340.1 - 0.095 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain C1_1 PF00130.22 GAN05341.1 - 3.5e-11 42.8 14.6 9.7e-07 28.6 3.8 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 GAN05341.1 - 8.4e-05 22.8 15.8 0.0019 18.5 4.0 2.8 2 0 0 2 2 2 2 C1 domain UNC-79 PF14776.6 GAN05341.1 - 0.0034 16.2 0.1 0.01 14.6 0.1 1.7 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 DEP PF00610.21 GAN05341.1 - 0.016 15.2 0.0 0.055 13.5 0.0 1.9 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PHD PF00628.29 GAN05341.1 - 0.094 12.6 13.0 0.58 10.1 1.1 2.6 2 0 0 2 2 2 0 PHD-finger Vac14_Fab1_bd PF12755.7 GAN05341.1 - 0.11 13.1 1.3 0.96 10.1 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region FYVE_2 PF02318.16 GAN05341.1 - 1.2 9.4 5.1 13 6.0 0.3 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger RPAP3_C PF13877.6 GAN05341.1 - 2 9.0 4.3 1.2e+02 3.4 0.2 4.2 4 0 0 4 4 4 0 Potential Monad-binding region of RPAP3 PC-Esterase PF13839.6 GAN05343.1 - 0.0031 17.3 1.5 0.0038 17.0 1.2 1.3 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PXA PF02194.15 GAN05343.1 - 0.89 9.5 6.6 0.34 10.9 0.2 2.1 1 1 1 2 2 2 0 PXA domain Renin_r PF07850.14 GAN05343.1 - 1.4 9.6 3.1 13 6.4 3.1 2.2 1 1 0 1 1 1 0 Renin receptor-like protein AMP-binding PF00501.28 GAN05345.1 - 7.4e-96 321.3 0.1 9.3e-96 321.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ATR13 PF16829.5 GAN05346.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 1 0 1 1 1 0 Avirulence protein ATR13, RxLR effector Pkinase PF00069.25 GAN05347.1 - 6.7e-45 153.5 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05347.1 - 1.1e-30 106.8 0.0 1.5e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05347.1 - 0.0047 16.3 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN05347.1 - 0.013 15.4 0.0 1.9 8.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN05347.1 - 0.049 12.4 1.4 0.07 11.9 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 GAN05347.1 - 0.071 12.0 0.2 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 GAN05347.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_CoA_synt_C PF08540.10 GAN05349.1 - 2.3e-98 329.3 3.1 3.1e-98 328.9 3.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 GAN05349.1 - 8.8e-88 292.7 0.5 1.4e-87 292.1 0.5 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 GAN05349.1 - 0.035 14.3 0.1 5.2 7.3 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Guanylate_cyc_2 PF09778.9 GAN05350.1 - 6.4e-69 231.5 0.5 7.7e-69 231.3 0.5 1.1 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 GAN05350.1 - 1.8e-08 35.1 0.0 0.0071 16.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.15 GAN05350.1 - 0.00033 20.5 0.0 0.03 14.1 0.0 3.1 3 0 0 3 3 3 1 Peptidase C39 family Peptidase_C70 PF12385.8 GAN05350.1 - 0.0045 17.0 0.0 0.099 12.6 0.0 2.1 2 0 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 Dynactin PF12455.8 GAN05351.1 - 1.5e-90 303.3 16.1 1.5e-90 303.3 16.1 5.6 4 2 1 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 GAN05351.1 - 2.2e-24 85.2 0.8 4.4e-24 84.3 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinesin PF00225.23 GAN05352.1 - 1.1e-110 369.7 1.2 1.1e-110 369.7 1.2 2.7 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAN05352.1 - 5.3e-29 101.1 0.2 5.3e-29 101.1 0.2 3.4 3 0 0 3 3 3 1 Microtubule binding WD40 PF00400.32 GAN05353.1 - 4e-15 55.9 8.3 4.9e-07 30.3 0.4 6.6 6 1 1 7 7 7 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 GAN05353.1 - 5.2e-08 32.4 12.2 5.2e-08 32.4 12.2 2.0 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 GAN05353.1 - 7.9e-07 29.3 0.2 0.099 13.0 0.0 4.4 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 GAN05353.1 - 0.0092 16.2 4.0 0.0092 16.2 4.0 2.5 1 1 1 2 2 2 1 Zinc-ribbon like family Nucleoporin_N PF08801.11 GAN05353.1 - 0.016 14.0 0.2 2 7.1 0.1 2.7 1 1 1 2 2 2 0 Nup133 N terminal like Rep_fac-A_C PF08646.10 GAN05353.1 - 0.73 9.6 4.6 1.7 8.4 4.6 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain PHD PF00628.29 GAN05353.1 - 2.5 8.0 12.8 0.48 10.4 3.2 2.8 2 1 0 2 2 2 0 PHD-finger GIT_SHD PF08518.11 GAN05354.1 - 2.3e-26 91.1 3.3 1.7e-14 53.1 0.3 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 GAN05354.1 - 2.2e-05 24.6 1.8 2.2e-05 24.6 1.8 3.7 3 1 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term Yuri_gagarin PF15934.5 GAN05354.1 - 0.0054 16.6 16.9 0.012 15.5 16.9 1.6 1 1 0 1 1 1 1 Yuri gagarin V_ATPase_I PF01496.19 GAN05354.1 - 0.1 10.5 15.0 0.21 9.5 15.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 GAN05354.1 - 3.4 8.3 17.3 2.5 8.8 7.9 3.8 1 1 1 3 3 3 0 SlyX LMBR1 PF04791.16 GAN05354.1 - 4.2 6.2 12.5 6 5.7 11.9 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein Tweety PF04906.13 GAN05354.1 - 4.5 5.8 8.2 5.7 5.5 0.1 2.6 2 0 0 2 2 2 0 Tweety HEAT_2 PF13646.6 GAN05355.1 - 3.7e-43 145.8 5.2 1.1e-14 54.6 0.1 3.8 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 GAN05355.1 - 1.2e-30 103.1 0.3 4.4e-05 23.7 0.0 6.7 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 GAN05355.1 - 6.1e-14 50.9 0.9 0.026 14.8 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 GAN05355.1 - 5e-05 23.7 1.5 0.42 11.2 0.0 4.7 3 1 2 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 GAN05355.1 - 0.00015 21.9 0.7 0.58 10.2 0.1 3.7 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAN05355.1 - 0.0028 17.6 0.2 0.43 10.7 0.0 3.2 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat SASP PF00269.20 GAN05355.1 - 0.31 11.1 1.9 43 4.2 0.1 3.8 3 1 0 3 3 3 0 Small, acid-soluble spore proteins, alpha/beta type AA_permease PF00324.21 GAN05356.1 - 2.4e-11 42.9 5.0 3.1e-11 42.5 5.0 1.0 1 0 0 1 1 1 1 Amino acid permease RRM_1 PF00076.22 GAN05359.1 - 1.2e-71 236.5 0.4 1.7e-19 69.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAN05359.1 - 1.4e-20 73.2 0.9 3.3e-20 72.0 0.9 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAN05359.1 - 7.3e-08 32.1 0.0 0.027 14.1 0.0 3.3 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN05359.1 - 8.5e-07 28.8 0.0 0.052 13.4 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GAN05359.1 - 1.5e-06 28.2 5.4 0.24 11.5 0.0 4.4 3 1 1 4 4 4 3 Limkain b1 YflT PF11181.8 GAN05359.1 - 2.4e-05 24.7 1.3 0.067 13.7 0.4 2.6 2 0 0 2 2 2 2 Heat induced stress protein YflT RRM_7 PF16367.5 GAN05359.1 - 3.2e-05 24.0 0.4 0.32 11.1 0.0 4.4 4 2 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 GAN05359.1 - 0.00031 20.7 0.1 2.3 8.3 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAN05359.1 - 0.0012 18.9 1.5 0.19 11.8 0.2 3.8 3 1 1 4 4 4 1 RNA binding motif OB_RNB PF08206.11 GAN05359.1 - 0.14 11.8 0.3 8.7 6.1 0.1 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain SET_assoc PF11767.8 GAN05359.1 - 0.24 11.1 3.6 38 4.0 0.0 3.8 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated DSPc PF00782.20 GAN05360.1 - 1.7e-07 31.1 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN05360.1 - 0.00038 20.1 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GAN05360.1 - 0.00039 20.1 0.3 0.0014 18.3 0.1 2.0 2 1 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) COG5 PF10392.9 GAN05361.1 - 1.9e-30 105.8 4.9 1.9e-30 105.8 4.9 2.7 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 GAN05361.1 - 1.9e-06 27.8 1.9 1.9e-06 27.8 1.9 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Vps54_N PF10475.9 GAN05361.1 - 0.038 13.3 14.4 0.02 14.2 10.0 2.6 2 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Ubiq_cyt_C_chap PF03981.12 GAN05361.1 - 0.059 13.5 0.1 0.88 9.7 0.0 2.9 3 1 0 3 3 3 0 Ubiquinol-cytochrome C chaperone COG2 PF06148.11 GAN05361.1 - 0.073 13.2 4.5 0.078 13.1 1.9 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Thioredoxin PF00085.20 GAN05361.1 - 0.11 12.4 1.1 2.2 8.3 0.1 2.9 2 0 0 2 2 2 0 Thioredoxin Phasin_2 PF09361.10 GAN05361.1 - 0.3 11.4 4.3 0.26 11.6 0.5 3.0 3 0 0 3 3 3 0 Phasin protein Fib_alpha PF08702.10 GAN05361.1 - 8.3 6.6 16.4 0.66 10.2 0.3 4.2 3 2 0 3 3 3 0 Fibrinogen alpha/beta chain family DHHC PF01529.20 GAN05362.1 - 0.14 12.2 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase FAM72 PF14976.6 GAN05363.1 - 9.8e-13 48.5 0.1 1.5e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 FAM72 protein Spt20 PF12090.8 GAN05363.1 - 2 8.0 10.5 2.5 7.7 10.5 1.2 1 0 0 1 1 1 0 Spt20 family NPR2 PF06218.11 GAN05364.1 - 3.3e-112 375.5 11.6 9.1e-88 294.9 11.1 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Afi1 PF07792.12 GAN05364.1 - 0.1 13.1 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.13 GAN05364.1 - 0.19 10.5 1.1 2.2 7.0 0.1 2.6 2 1 1 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Polysacc_deac_1 PF01522.21 GAN05365.1 - 7.2e-30 103.4 0.0 1.2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN05365.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Luteo_Vpg PF01659.16 GAN05365.1 - 3.9 7.9 7.1 5.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Luteovirus putative VPg genome linked protein zf-Tim10_DDP PF02953.15 GAN05366.1 - 2e-17 62.6 2.5 3e-17 62.0 2.5 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 GAN05366.1 - 0.0043 16.8 4.4 0.64 9.7 0.2 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF842) ATG13 PF10033.9 GAN05367.1 - 3.5e-68 229.9 0.7 3.5e-68 229.9 0.7 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 Actin PF00022.19 GAN05368.1 - 3e-58 197.4 0.0 3e-35 121.6 0.0 2.4 2 1 0 2 2 2 2 Actin DUF2589 PF11655.8 GAN05368.1 - 0.25 11.7 5.0 2.9 8.2 4.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2589) FERM_M PF00373.18 GAN05368.1 - 3.5 8.1 7.7 9.1 6.7 0.0 3.3 3 1 0 3 3 3 0 FERM central domain MOZ_SAS PF01853.18 GAN05369.1 - 3.8e-58 196.1 0.9 1.5e-57 194.2 0.9 1.8 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAN05369.1 - 8.4e-20 70.1 1.1 2.1e-19 68.8 1.1 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 GAN05369.1 - 0.00022 21.6 0.0 0.00044 20.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN05369.1 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAN05369.1 - 0.0069 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Pex14_N PF04695.13 GAN05370.1 - 4.8e-30 105.3 2.9 4.8e-30 105.3 2.9 4.1 3 2 0 4 4 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 GAN05370.1 - 2.8e-05 24.1 1.1 6.8e-05 22.9 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF812 PF05667.11 GAN05370.1 - 9.3e-05 21.5 1.4 0.00013 21.1 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) XhlA PF10779.9 GAN05370.1 - 0.0016 18.6 12.9 0.07 13.3 0.7 3.5 1 1 2 3 3 3 2 Haemolysin XhlA LXG PF04740.12 GAN05370.1 - 0.012 15.4 7.7 0.012 15.4 7.7 1.8 2 1 0 2 2 1 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.12 GAN05370.1 - 0.018 15.0 1.8 0.018 15.0 1.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cir_Bir_Yir PF06022.11 GAN05370.1 - 0.021 14.3 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Exog_C PF18026.1 GAN05370.1 - 0.033 14.2 0.1 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain SKA2 PF16740.5 GAN05370.1 - 0.046 13.5 8.0 0.76 9.6 0.5 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3584 PF12128.8 GAN05370.1 - 0.055 11.0 9.0 0.079 10.5 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 GAN05370.1 - 0.065 13.3 7.0 0.11 12.5 7.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fmp27_WPPW PF10359.9 GAN05370.1 - 0.069 12.0 4.2 0.11 11.3 4.2 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tektin PF03148.14 GAN05370.1 - 0.095 11.4 9.3 0.03 13.1 4.8 2.0 1 1 1 2 2 2 0 Tektin family IFT57 PF10498.9 GAN05370.1 - 0.1 11.5 6.9 0.19 10.6 6.9 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CdvA PF18822.1 GAN05370.1 - 0.13 12.1 11.5 0.76 9.6 9.5 2.6 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Img2 PF05046.14 GAN05370.1 - 0.15 12.4 0.5 0.51 10.7 0.2 1.9 2 1 1 3 3 2 0 Mitochondrial large subunit ribosomal protein (Img2) EzrA PF06160.12 GAN05370.1 - 0.16 10.1 8.1 0.27 9.3 8.1 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF5320 PF17253.2 GAN05370.1 - 0.19 12.8 2.0 0.43 11.7 0.0 2.5 3 1 0 3 3 1 0 Family of unknown function (DUF5320) DUF1043 PF06295.12 GAN05370.1 - 0.2 11.7 3.5 0.56 10.2 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Laminin_II PF06009.12 GAN05370.1 - 0.24 11.4 11.4 0.093 12.8 8.3 1.9 2 1 0 2 2 1 0 Laminin Domain II Spc7 PF08317.11 GAN05370.1 - 0.25 10.2 10.7 0.58 9.0 10.7 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 GAN05370.1 - 0.3 11.3 9.9 0.67 10.1 9.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 GAN05370.1 - 0.33 10.7 6.5 0.21 11.4 3.5 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 GAN05370.1 - 0.38 10.0 5.9 0.59 9.3 5.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein TolA_bind_tri PF16331.5 GAN05370.1 - 0.47 10.6 4.6 2.3 8.4 0.2 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation Tropomyosin PF00261.20 GAN05370.1 - 0.58 9.5 15.7 0.21 10.9 13.1 1.4 2 0 0 2 2 1 0 Tropomyosin DUF4200 PF13863.6 GAN05370.1 - 0.77 10.2 11.8 0.29 11.5 7.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 GAN05370.1 - 1.1 9.8 14.5 15 6.1 14.5 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Flagellar_rod PF05149.12 GAN05370.1 - 1.1 8.7 9.2 1.3 8.4 3.0 2.1 1 1 1 2 2 2 0 Paraflagellar rod protein COG2 PF06148.11 GAN05370.1 - 1.5 8.9 6.0 0.78 9.8 2.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.13 GAN05370.1 - 2.4 8.3 9.3 10 6.3 5.5 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 GAN05370.1 - 2.7 7.3 15.9 0.86 8.9 2.4 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding E2F_CC-MB PF16421.5 GAN05370.1 - 2.7 8.4 8.5 3.4 8.1 2.3 2.5 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain Sec20 PF03908.13 GAN05370.1 - 3.1 7.8 5.6 6.1 6.8 3.4 2.3 1 1 1 2 2 2 0 Sec20 BRE1 PF08647.11 GAN05370.1 - 3.1 7.9 12.4 28 4.9 12.1 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 GAN05370.1 - 3.9 8.0 15.6 89 3.7 0.5 3.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.9 GAN05370.1 - 4 7.7 14.6 0.22 11.8 6.6 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein CLZ PF16526.5 GAN05370.1 - 4.1 7.8 7.8 0.47 10.9 1.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 GAN05370.1 - 6.6 6.6 11.1 10 6.0 0.6 3.3 2 1 1 3 3 3 0 Septum formation initiator SLX9 PF15341.6 GAN05370.1 - 6.8 7.1 12.3 89 3.5 12.3 2.4 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 SKA1 PF07160.12 GAN05370.1 - 6.9 6.4 10.0 1.1e+02 2.6 10.0 2.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF16 PF01519.16 GAN05370.1 - 7.1 7.2 14.7 2e+02 2.5 14.7 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.11 GAN05370.1 - 8.6 6.7 14.4 0.35 11.2 3.6 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Pro_isomerase PF00160.21 GAN05371.1 - 1.2e-46 158.8 0.1 1.4e-46 158.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med25_VWA PF11265.8 GAN05372.1 - 4.2e-25 88.8 0.0 9e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A 2-oxoacid_dh PF00198.23 GAN05373.1 - 1.3e-71 240.8 0.0 1.7e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAN05373.1 - 3e-16 59.0 0.0 5.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAN05373.1 - 2.6e-10 40.5 0.1 1.3e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 e3 binding domain C2 PF00168.30 GAN05374.1 - 5.1e-90 296.5 2.9 2.3e-20 72.8 0.1 6.4 6 0 0 6 6 6 6 C2 domain Pkinase PF00069.25 GAN05375.1 - 1.2e-71 241.2 1.0 2e-71 240.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05375.1 - 7.3e-48 163.1 0.0 1.7e-47 161.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAN05375.1 - 1.2e-21 76.8 3.2 1.5e-21 76.5 0.0 2.9 4 0 0 4 4 4 1 P21-Rho-binding domain Kinase-like PF14531.6 GAN05375.1 - 1.4e-05 24.5 0.0 1.4e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAN05375.1 - 0.0011 17.8 15.0 0.012 14.5 14.1 2.4 1 1 0 1 1 1 1 Fungal protein kinase DSHCT PF08148.12 GAN05375.1 - 0.33 10.6 4.7 0.11 12.2 0.3 2.3 2 1 0 2 2 2 0 DSHCT (NUC185) domain APH PF01636.23 GAN05375.1 - 7.2 6.4 11.4 2 8.3 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Bot1p PF12298.8 GAN05378.1 - 1.6e-15 57.7 0.5 2.8e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 GAN05378.1 - 1.8e-05 25.0 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 TIP49 PF06068.13 GAN05379.1 - 7.2e-162 538.5 1.7 1e-161 538.0 1.7 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAN05379.1 - 1.5e-28 98.7 0.3 3.5e-28 97.5 0.3 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAN05379.1 - 3.8e-08 33.8 2.5 6.2e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAN05379.1 - 1.6e-07 31.2 0.8 0.0026 17.5 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 GAN05379.1 - 6.1e-06 25.8 0.4 1.2e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 GAN05379.1 - 2.9e-05 24.5 0.0 0.00011 22.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAN05379.1 - 3.5e-05 23.8 0.2 0.15 12.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAN05379.1 - 0.00043 19.7 1.2 0.029 13.7 0.5 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAN05379.1 - 0.0013 18.7 0.2 1.1 9.3 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 GAN05379.1 - 0.0015 18.8 0.3 0.12 12.7 0.0 2.7 3 1 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 GAN05379.1 - 0.002 17.8 0.3 3.8 7.2 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_25 PF13481.6 GAN05379.1 - 0.0024 17.5 0.1 0.014 15.0 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAN05379.1 - 0.011 16.1 5.4 0.017 15.4 2.3 2.6 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 GAN05379.1 - 0.046 12.8 0.2 0.1 11.7 0.1 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 GAN05379.1 - 0.052 13.8 0.1 0.052 13.8 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 GAN05379.1 - 0.076 12.8 0.3 0.23 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAN05379.1 - 0.14 11.6 0.3 0.79 9.2 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAN05379.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain GPI-anchored PF10342.9 GAN05381.1 - 0.00072 20.3 0.4 0.0023 18.6 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family C2 PF00168.30 GAN05382.1 - 4.5e-26 91.1 0.2 5.3e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 C2 domain Ecl1 PF12855.7 GAN05383.1 - 0.00021 22.5 20.9 0.00039 21.6 20.9 1.4 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 GAN05383.1 - 0.36 11.2 6.4 0.12 12.7 3.5 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Cnn_1N PF07989.11 GAN05385.1 - 1.2e-05 25.4 0.8 1.2e-05 25.4 0.8 10.7 5 2 3 8 8 8 2 Centrosomin N-terminal motif 1 ABC_tran_CTD PF16326.5 GAN05385.1 - 0.015 15.5 9.7 0.015 15.5 9.7 8.7 6 3 2 8 8 8 0 ABC transporter C-terminal domain PLA2_inh PF02988.15 GAN05385.1 - 1.1 9.9 5.5 0.61 10.8 0.3 2.8 3 0 0 3 3 3 0 Phospholipase A2 inhibitor AAA_6 PF12774.7 GAN05386.1 - 1.1e-131 438.7 0.9 6.1e-129 429.7 0.0 4.3 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 GAN05386.1 - 1e-122 410.7 14.5 1e-122 410.7 14.5 3.6 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 GAN05386.1 - 2.2e-118 395.8 4.9 2.2e-118 395.8 4.9 7.0 6 2 1 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 GAN05386.1 - 1.7e-75 253.0 0.3 1.7e-75 253.0 0.3 4.5 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 GAN05386.1 - 1.9e-68 230.6 0.0 6.3e-68 228.9 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 GAN05386.1 - 1.1e-48 166.1 3.6 4.4e-48 164.1 3.7 2.1 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 GAN05386.1 - 2.6e-42 145.1 7.6 2.6e-42 145.1 7.6 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 GAN05386.1 - 2.5e-41 141.2 0.0 5.8e-35 120.4 0.0 5.0 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 GAN05386.1 - 4.8e-37 127.3 0.0 1.3e-36 125.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GAN05386.1 - 2.6e-30 104.9 0.0 1.1e-28 99.7 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 GAN05386.1 - 1.7e-28 99.4 0.0 1.8e-11 44.2 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 GAN05386.1 - 8.4e-20 71.2 0.2 2e-18 66.7 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 GAN05386.1 - 6e-15 55.7 0.3 0.0045 17.3 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA PF00004.29 GAN05386.1 - 8.6e-13 48.9 0.0 0.0059 17.0 0.0 5.3 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAN05386.1 - 1.5e-10 41.4 0.5 0.065 13.4 0.0 5.2 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 GAN05386.1 - 1.7e-08 35.0 0.0 0.72 10.2 0.0 6.1 5 0 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.6 GAN05386.1 - 2.3e-08 34.7 0.7 0.26 11.8 0.0 6.2 5 0 0 5 5 5 2 AAA domain AAA_lid_1 PF17857.1 GAN05386.1 - 1.7e-06 28.1 0.0 3.1e-05 24.1 0.0 3.0 2 0 0 2 2 2 1 AAA+ lid domain T2SSE PF00437.20 GAN05386.1 - 3.9e-06 26.1 0.0 0.026 13.6 0.0 4.0 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.27 GAN05386.1 - 4.8e-06 27.1 0.1 0.38 11.3 0.0 5.1 4 0 0 4 4 3 1 ABC transporter Mg_chelatase PF01078.21 GAN05386.1 - 1.3e-05 24.7 0.6 1 8.7 0.0 3.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 GAN05386.1 - 1.4e-05 24.8 0.1 0.7 9.7 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GAN05386.1 - 4.5e-05 22.9 0.0 2.8 7.2 0.0 4.5 4 0 0 4 4 4 2 FtsK/SpoIIIE family AAA_30 PF13604.6 GAN05386.1 - 5.1e-05 23.1 0.2 8.6 6.0 0.0 4.7 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 GAN05386.1 - 0.00049 20.1 0.0 7.1 6.5 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_19 PF13245.6 GAN05386.1 - 0.00091 19.6 1.4 0.31 11.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 GAN05386.1 - 0.0019 18.0 0.7 57 3.4 0.0 5.0 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 GAN05386.1 - 0.002 17.9 1.1 0.54 10.0 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 GAN05386.1 - 0.003 17.5 0.0 6.8 6.6 0.0 3.9 3 0 0 3 3 3 0 RsgA GTPase RNA_helicase PF00910.22 GAN05386.1 - 0.0037 17.6 0.0 4.3 7.8 0.0 4.5 4 0 0 4 4 4 1 RNA helicase AAA_25 PF13481.6 GAN05386.1 - 0.0073 15.9 0.0 0.42 10.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 GAN05386.1 - 0.05 13.5 0.4 54 3.6 0.1 4.1 3 0 0 3 3 3 0 NACHT domain POT1PC PF16686.5 GAN05386.1 - 0.074 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein DUF948 PF06103.11 GAN05386.1 - 5.8 7.2 9.7 9.6 6.5 0.6 5.9 6 0 0 6 6 5 0 Bacterial protein of unknown function (DUF948) HLH PF00010.26 GAN05387.1 - 5.1e-17 61.6 0.9 5.1e-17 61.6 0.9 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1978 PF09321.10 GAN05387.1 - 0.0075 15.6 2.1 0.013 14.8 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) DUF4666 PF15697.5 GAN05387.1 - 0.034 14.8 2.3 0.034 14.8 2.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4666) Mis12 PF05859.12 GAN05387.1 - 0.17 11.9 2.0 0.45 10.6 0.1 2.2 2 0 0 2 2 2 0 Mis12 protein ETC_C1_NDUFA5 PF04716.14 GAN05387.1 - 0.37 10.6 2.2 5.4 6.9 0.2 2.5 2 0 0 2 2 2 0 ETC complex I subunit conserved region Pep_M12B_propep PF01562.19 GAN05387.1 - 2.6 8.3 8.9 0.092 13.0 1.3 2.3 3 0 0 3 3 3 0 Reprolysin family propeptide HTH_ABP1_N PF18107.1 GAN05388.1 - 2.5e-05 23.9 0.7 5.5e-05 22.8 0.7 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 GAN05388.1 - 4.2e-05 23.5 0.0 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-RING_5 PF14634.6 GAN05390.1 - 0.25 11.3 2.5 0.52 10.3 2.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain ADH_N PF08240.12 GAN05391.1 - 5.6e-31 106.7 1.3 5.6e-31 106.7 1.3 2.0 3 0 0 3 3 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN05391.1 - 2.9e-18 66.1 0.1 5.2e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAN05391.1 - 3.2e-11 43.1 0.1 5e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 GAN05391.1 - 0.00038 19.3 0.2 0.00064 18.5 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAN05391.1 - 0.00057 19.2 1.2 0.00093 18.5 0.6 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain YdfZ PF14001.6 GAN05391.1 - 0.00072 19.9 0.0 0.0032 17.9 0.0 2.1 2 0 0 2 2 1 1 YdfZ protein FAD_binding_3 PF01494.19 GAN05391.1 - 0.0014 18.0 0.7 0.0042 16.4 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 GAN05391.1 - 0.0016 19.0 0.2 0.0035 17.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 GAN05391.1 - 0.007 17.4 0.1 0.024 15.7 0.0 1.9 1 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 GAN05391.1 - 0.0095 16.4 0.0 0.024 15.1 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 GAN05391.1 - 0.023 13.9 0.3 0.039 13.2 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 GAN05391.1 - 0.027 15.0 0.1 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_2 PF00890.24 GAN05391.1 - 0.028 13.5 0.8 0.26 10.3 0.6 2.0 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 GAN05391.1 - 0.032 14.3 0.1 0.065 13.3 0.0 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 GAN05391.1 - 0.041 13.5 0.3 0.067 12.8 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN05391.1 - 0.044 14.0 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAN05391.1 - 0.15 11.3 1.1 0.26 10.5 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAN05391.1 - 0.16 11.4 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAN05391.1 - 0.29 11.0 1.5 0.29 11.0 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 GAN05392.1 - 1.1e-92 311.3 20.1 2.1e-91 307.1 20.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN05392.1 - 4.6e-24 85.0 29.6 1e-22 80.6 17.1 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 GAN05392.1 - 6.6e-06 25.1 0.6 9.9e-06 24.5 0.6 1.3 1 0 0 1 1 1 1 Reduced folate carrier GCP_N_terminal PF17681.1 GAN05393.1 - 1.1e-31 110.6 8.4 1.1e-31 110.6 8.4 2.3 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAN05393.1 - 2e-26 93.2 7.1 2e-26 93.2 7.1 2.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Ribosomal_L30 PF00327.20 GAN05394.1 - 6.7e-12 45.1 0.1 9.1e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Glyco_transf_17 PF04724.13 GAN05395.1 - 1.7e-141 471.3 4.0 7.6e-97 324.5 1.1 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 17 Kinesin PF00225.23 GAN05396.1 - 2.8e-112 375.0 1.8 2.8e-112 375.0 1.8 2.5 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAN05396.1 - 5e-28 97.9 3.1 7.6e-28 97.3 0.2 2.8 2 0 0 2 2 2 1 Microtubule binding CENP-H PF05837.12 GAN05396.1 - 0.0079 16.6 9.0 0.0079 16.6 9.0 6.2 2 2 3 5 5 5 1 Centromere protein H (CENP-H) IFT57 PF10498.9 GAN05396.1 - 0.38 9.7 76.0 0.77 8.7 13.3 5.7 3 1 3 6 6 6 0 Intra-flagellar transport protein 57 Flu_B_M2 PF04772.12 GAN05396.1 - 0.56 10.5 4.8 0.17 12.2 0.3 2.5 2 1 0 2 2 2 0 Influenza B matrix protein 2 (BM2) TFA2_Winged_2 PF18121.1 GAN05396.1 - 9.8 6.0 9.9 2.3 8.0 2.5 3.9 4 2 0 4 4 4 0 TFA2 Winged helix domain 2 BBL5 PF07289.11 GAN05398.1 - 0.11 11.5 0.1 11 5.0 0.0 2.1 2 0 0 2 2 2 0 Bardet-Biedl syndrome 5 protein IMS PF00817.20 GAN05400.1 - 8.5e-41 139.4 0.0 1.6e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 GAN05400.1 - 1.8e-13 49.8 1.1 4.2e-13 48.6 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 GAN05400.1 - 7.7e-08 33.0 0.0 2.3e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 impB/mucB/samB family C-terminal domain DUF5327 PF17261.2 GAN05400.1 - 1.7 9.4 4.6 0.41 11.4 0.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5327) SH3_9 PF14604.6 GAN05401.1 - 2.1e-11 43.5 0.0 3.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN05401.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain VSP PF03302.13 GAN05401.1 - 0.00031 19.7 6.5 0.00031 19.7 6.5 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein EphA2_TM PF14575.6 GAN05401.1 - 0.001 19.9 1.1 0.0056 17.5 0.0 2.3 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 GAN05401.1 - 0.0018 18.5 5.0 0.13 12.5 5.3 2.2 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SH3_2 PF07653.17 GAN05401.1 - 0.0059 16.3 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain TMEM154 PF15102.6 GAN05401.1 - 0.006 16.5 0.6 0.006 16.5 0.6 3.4 1 1 1 3 3 2 1 TMEM154 protein family Insulin_TMD PF17870.1 GAN05401.1 - 0.033 14.2 3.8 0.082 13.0 3.8 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SpoIIIAH PF12685.7 GAN05401.1 - 0.099 12.5 18.1 2 8.2 0.4 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein YajC PF02699.15 GAN05401.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.1 2 1 0 2 2 1 0 Preprotein translocase subunit O-antigen_lig PF13425.6 GAN05401.1 - 0.47 9.2 1.5 18 3.9 1.3 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein RIFIN PF02009.16 GAN05401.1 - 0.8 9.5 23.3 3.6 7.4 14.1 2.9 2 1 0 2 2 2 0 Rifin DUF4064 PF13273.6 GAN05401.1 - 1 9.7 6.2 0.3 11.4 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2500 PF10694.9 GAN05401.1 - 2.3 8.8 7.5 6.7 7.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2500) DUF5385 PF17359.2 GAN05401.1 - 2.5 7.6 6.6 3.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NrsF PF06532.11 GAN05401.1 - 2.9 7.6 7.4 0.68 9.6 2.7 2.1 3 0 0 3 3 3 0 Negative regulator of sigma F SAPS PF04499.15 GAN05401.1 - 5.7 5.6 7.1 17 4.0 5.2 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PDGLE PF13190.6 GAN05401.1 - 5.9 6.9 7.6 26 4.8 3.7 3.0 2 1 0 2 2 2 0 PDGLE domain DUF702 PF05142.12 GAN05401.1 - 6.6 7.2 10.3 12 6.4 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) zf-C2H2_aberr PF17017.5 GAN05402.1 - 1.3e-06 28.7 3.4 0.022 14.9 0.9 2.5 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 GAN05402.1 - 2e-05 24.8 12.3 0.019 15.4 0.8 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN05402.1 - 0.0069 17.1 14.5 0.045 14.6 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN05402.1 - 0.056 13.9 10.9 0.44 11.1 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double domain ARS2 PF04959.13 GAN05402.1 - 0.11 12.8 0.1 1.2 9.4 0.1 2.1 1 1 1 2 2 2 0 Arsenite-resistance protein 2 zf_C2H2_ZHX PF18387.1 GAN05402.1 - 2.2 8.0 10.3 9.6 5.9 0.2 3.3 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Gemin7 PF11095.8 GAN05403.1 - 4.1e-16 58.6 0.0 5.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) CPSase_L_D2 PF02786.17 GAN05404.1 - 9.8e-113 374.8 0.5 2.1e-83 279.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAN05404.1 - 1.6e-47 160.5 0.0 3.5e-47 159.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAN05404.1 - 7.5e-47 159.6 0.0 1.5e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 GAN05404.1 - 8e-45 152.5 0.0 1.7e-44 151.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 GAN05404.1 - 3.5e-40 137.2 0.0 9.7e-40 135.7 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 GAN05404.1 - 1.3e-34 119.6 0.1 1.9e-33 115.8 0.1 2.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 GAN05404.1 - 2.3e-19 69.4 0.0 1.4e-18 66.9 0.0 2.5 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 GAN05404.1 - 2.2e-18 66.5 1.6 1.9e-10 40.6 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAN05404.1 - 4.5e-15 55.7 0.2 1.3e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 GAN05404.1 - 2.9e-09 36.8 0.0 0.00041 20.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 GAN05404.1 - 7.4e-07 29.4 3.0 0.0048 17.0 0.1 3.7 4 0 0 4 4 4 2 ATP-grasp domain Peptidase_C26 PF07722.13 GAN05404.1 - 9.1e-05 22.3 0.3 0.0046 16.7 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 HTH_37 PF13744.6 GAN05406.1 - 0.06 13.3 0.0 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain B5 PF03484.15 GAN05406.1 - 0.11 12.9 0.0 0.35 11.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase B5 domain HTH_28 PF13518.6 GAN05406.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 GAN05406.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DUF2370 PF10176.9 GAN05407.1 - 5.8e-71 238.7 7.7 7.5e-70 235.1 0.8 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2370) TMEM252 PF15664.5 GAN05407.1 - 0.037 13.7 0.4 8.8 6.1 0.2 2.6 2 0 0 2 2 2 0 Transmembrane protein 252 family PalH PF08733.10 GAN05407.1 - 0.067 12.2 0.1 0.13 11.2 0.0 1.4 2 0 0 2 2 2 0 PalH/RIM21 RGS PF00615.19 GAN05408.1 - 7.9e-19 68.1 0.1 1.3e-18 67.3 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_S7 PF00949.21 GAN05408.1 - 0.13 12.1 2.3 0.23 11.3 2.3 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease PDEase_I PF00233.19 GAN05409.1 - 4.5e-67 226.2 2.7 6.8e-67 225.7 2.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 GAN05409.1 - 9.9e-09 35.5 2.1 1.3e-08 35.1 0.7 2.0 2 1 0 2 2 2 1 HD domain Mucin PF01456.17 GAN05409.1 - 4.2 7.4 14.9 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Septin PF00735.18 GAN05410.1 - 1.5e-111 372.2 0.2 2.1e-111 371.7 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN05410.1 - 1.3e-07 31.7 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN05410.1 - 1.6e-06 27.8 4.6 2.2e-06 27.3 0.2 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN05410.1 - 5.6e-06 26.4 3.0 1.3e-05 25.1 0.2 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 GAN05410.1 - 2e-05 24.5 0.0 4.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 GAN05410.1 - 0.00012 22.2 0.1 0.00033 20.9 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN05410.1 - 0.00019 21.1 1.1 0.00061 19.4 0.7 2.1 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.6 GAN05410.1 - 0.0024 18.2 1.3 0.0068 16.7 0.2 2.2 2 1 0 3 3 3 1 AAA domain IIGP PF05049.13 GAN05410.1 - 0.0041 16.2 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 GAN05410.1 - 0.0053 16.5 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain Pox_A32 PF04665.12 GAN05410.1 - 0.0057 16.1 0.3 0.029 13.8 0.1 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein AIG1 PF04548.16 GAN05410.1 - 0.0063 15.9 0.1 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 AIG1 family IstB_IS21 PF01695.17 GAN05410.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Gtr1_RagA PF04670.12 GAN05410.1 - 0.014 14.8 0.3 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 GAN05410.1 - 0.015 14.4 0.4 0.029 13.4 0.2 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 GAN05410.1 - 0.016 15.6 0.5 0.035 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 GAN05410.1 - 0.017 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 GAN05410.1 - 0.021 15.4 1.2 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 GAN05410.1 - 0.048 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 GAN05410.1 - 0.049 13.4 3.2 2 8.1 0.4 3.0 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAN05410.1 - 0.054 13.9 1.1 0.16 12.4 0.1 2.3 2 1 1 3 3 2 0 RNA helicase AAA_33 PF13671.6 GAN05410.1 - 0.082 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAN05410.1 - 0.095 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GAN05410.1 - 0.1 12.6 5.9 1.2 9.2 0.1 3.1 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.12 GAN05410.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Fzo_mitofusin PF04799.13 GAN05410.1 - 1 8.9 3.8 0.31 10.6 0.9 1.5 2 0 0 2 2 2 0 fzo-like conserved region GTP_EFTU PF00009.27 GAN05411.1 - 8.8e-63 211.4 0.2 1.4e-62 210.7 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 GAN05411.1 - 4e-26 90.9 0.0 8.1e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAN05411.1 - 7.7e-18 64.3 0.0 1.3e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAN05411.1 - 1.2e-10 41.6 1.2 2.9e-10 40.4 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 GAN05411.1 - 1.7e-08 34.2 0.1 2.3e-05 24.2 0.0 2.9 1 1 0 2 2 2 2 Elongation factor G, domain IV RF3_C PF16658.5 GAN05411.1 - 7e-08 32.4 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAN05411.1 - 0.0015 18.6 0.0 0.0047 17.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2407_C PF13373.6 GAN05411.1 - 0.0067 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain YjgF_endoribonc PF14588.6 GAN05411.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease SpoU_methylase PF00588.19 GAN05412.1 - 4.9e-32 111.0 0.1 2.5e-31 108.7 0.0 2.1 2 1 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAN05412.1 - 2e-15 56.8 0.1 3.6e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF190 PF02641.15 GAN05412.1 - 0.052 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 RAI16-like PF10257.9 GAN05413.1 - 1e-47 162.8 1.9 1e-47 162.8 1.9 1.5 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein HEPN_RES_NTD1 PF18870.1 GAN05413.1 - 0.023 14.9 0.0 18 5.5 0.0 3.1 3 0 0 3 3 3 0 HEPN/RES N-terminal domain 1 CRA PF06589.11 GAN05414.1 - 2.3 8.3 7.7 0.54 10.4 3.1 2.2 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF4407 PF14362.6 GAN05414.1 - 4 6.7 9.0 6.3 6.1 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CS PF04969.16 GAN05415.1 - 0.051 14.6 1.6 0.12 13.4 0.7 2.2 2 1 0 2 2 2 0 CS domain Topoisom_I PF01028.20 GAN05416.1 - 4.2e-97 324.0 6.2 4.2e-97 324.0 6.2 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 GAN05416.1 - 5.9e-96 320.1 3.5 5.9e-96 320.1 3.5 2.7 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 GAN05416.1 - 3.5e-34 116.5 0.6 1.2e-33 114.8 0.6 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4718 PF15842.5 GAN05416.1 - 2.5 7.9 7.5 0.19 11.5 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Y_phosphatase2 PF03162.13 GAN05417.1 - 1.5e-33 115.7 0.2 2e-33 115.3 0.2 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAN05417.1 - 0.019 14.9 0.0 0.023 14.7 0.0 1.2 1 1 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 GAN05417.1 - 0.063 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain EF_assoc_2 PF08356.12 GAN05417.1 - 0.11 12.5 0.5 4.1 7.5 0.0 2.5 3 0 0 3 3 3 0 EF hand associated Homeodomain PF00046.29 GAN05419.1 - 2.2e-15 56.2 2.4 6.3e-15 54.8 2.4 1.8 1 0 0 1 1 1 1 Homeodomain HTH_AsnC-type PF13404.6 GAN05419.1 - 0.0073 16.1 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 GAN05419.1 - 0.021 14.6 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox_KN PF05920.11 GAN05419.1 - 0.04 13.8 0.0 0.04 13.8 0.0 2.6 3 0 0 3 3 3 0 Homeobox KN domain Peptidase_S64 PF08192.11 GAN05419.1 - 0.58 8.6 11.6 0.64 8.4 11.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Eapp_C PF10238.9 GAN05419.1 - 0.64 10.1 9.8 1.3 9.1 9.8 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Membralin PF09746.9 GAN05419.1 - 9.6 5.1 8.3 12 4.8 8.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4451 PF14616.6 GAN05420.1 - 9.2e-20 71.1 1.6 2.8e-19 69.5 1.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) PBP1_TM PF14812.6 GAN05420.1 - 0.78 10.1 7.0 2.3 8.6 7.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WWE PF02825.20 GAN05421.1 - 0.051 14.2 0.0 0.091 13.4 0.0 1.4 1 0 0 1 1 1 0 WWE domain MAT1 PF06391.13 GAN05422.1 - 2.4e-54 184.3 26.1 3.3e-54 183.8 26.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 GAN05422.1 - 3.7e-20 71.5 7.0 3.7e-20 71.5 7.0 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN05422.1 - 6.7e-07 29.1 6.2 1.6e-06 27.8 6.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN05422.1 - 9.5e-07 28.7 8.1 9.8e-06 25.4 8.5 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAN05422.1 - 7.4e-06 25.7 5.8 2.1e-05 24.3 5.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN05422.1 - 9.3e-06 25.9 7.3 1.7e-05 25.1 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN05422.1 - 0.00013 21.7 10.1 0.00057 19.7 10.4 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN05422.1 - 0.00024 20.9 10.9 0.0094 15.8 11.2 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAN05422.1 - 0.00028 20.8 8.0 0.002 18.1 3.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAN05422.1 - 0.00078 19.2 4.3 0.033 14.0 1.5 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain GAGA PF09237.11 GAN05422.1 - 0.0077 16.0 7.5 0.029 14.2 1.2 3.2 3 0 0 3 3 3 1 GAGA factor Rad50_zn_hook PF04423.14 GAN05422.1 - 0.27 11.1 7.6 7 6.6 0.0 4.0 3 1 0 3 3 3 0 Rad50 zinc hook motif zf-WRNIP1_ubi PF18279.1 GAN05422.1 - 0.27 12.0 5.7 8.5 7.3 1.0 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-ANAPC11 PF12861.7 GAN05422.1 - 0.32 11.1 2.0 0.6 10.2 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Selenoprotein_S PF06936.11 GAN05422.1 - 0.6 9.9 15.2 0.98 9.2 15.2 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) SID-1_RNA_chan PF13965.6 GAN05422.1 - 0.69 8.3 2.9 0.8 8.0 2.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Senescence_reg PF04520.13 GAN05422.1 - 1.3 9.8 9.7 2.1 9.1 9.7 1.3 1 0 0 1 1 1 0 Senescence regulator Not1 PF04054.15 GAN05422.1 - 2.3 7.0 8.2 4 6.2 8.2 1.3 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DUF3797 PF12677.7 GAN05422.1 - 2.7 8.0 5.2 0.32 10.9 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-C3HC4_4 PF15227.6 GAN05422.1 - 3 8.1 9.4 40 4.5 10.0 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING SRP19 PF01922.17 GAN05423.1 - 3.7e-29 101.5 0.2 7.7e-29 100.5 0.2 1.5 1 0 0 1 1 1 1 SRP19 protein Pex19 PF04614.12 GAN05423.1 - 0.54 10.0 6.8 7.1 6.3 1.8 2.3 2 0 0 2 2 2 0 Pex19 protein family EMP24_GP25L PF01105.24 GAN05424.1 - 1e-48 165.7 2.6 1.1e-48 165.6 2.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1344 PF07076.11 GAN05424.1 - 0.043 13.7 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF4337 PF14235.6 GAN05424.1 - 0.066 13.3 0.2 0.08 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1408 PF07193.11 GAN05424.1 - 0.082 13.0 0.5 0.23 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) DUF1871 PF08958.10 GAN05424.1 - 0.1 12.9 0.3 1.2 9.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1871) Aldo_ket_red PF00248.21 GAN05425.1 - 6.6e-06 25.5 0.0 6.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 GAN05426.1 - 3e-46 157.9 0.0 5.1e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05426.1 - 1.5e-20 73.6 0.0 2.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN05426.1 - 7.6e-06 26.0 0.0 2.2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN05426.1 - 0.00073 18.6 0.1 0.0019 17.2 0.1 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN05426.1 - 0.0033 16.8 0.0 0.013 14.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like DUF1687 PF07955.11 GAN05427.1 - 2.5e-14 53.9 0.2 3.7e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 GAN05427.1 - 2.7e-05 24.1 0.0 4.3e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 ArsC family Aconitase PF00330.20 GAN05428.1 - 2.8e-153 511.2 0.0 3.5e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAN05428.1 - 8.1e-42 142.6 0.0 1.4e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L1 PF00687.21 GAN05429.1 - 3.2e-38 131.5 2.7 1.8e-32 112.7 0.8 2.1 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family Dicer_dimer PF03368.14 GAN05429.1 - 0.0087 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Dicer dimerisation domain DUF3671 PF12420.8 GAN05429.1 - 0.13 12.4 2.3 0.2 11.7 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function Dynamin_N PF00350.23 GAN05430.1 - 5.9e-45 153.3 0.0 5.9e-45 153.3 0.0 2.8 4 0 0 4 4 4 1 Dynamin family Dynamin_M PF01031.20 GAN05430.1 - 1.5e-18 67.0 2.6 5.7e-16 58.6 0.0 3.0 3 1 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.23 GAN05430.1 - 3.2e-06 27.2 0.1 3.5e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase SPT6_acidic PF14632.6 GAN05430.1 - 0.00059 20.4 2.9 0.00059 20.4 2.9 2.6 2 0 0 2 2 2 1 Acidic N-terminal SPT6 AAA_21 PF13304.6 GAN05430.1 - 0.0054 16.6 0.4 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ComJ PF11033.8 GAN05430.1 - 0.015 15.0 0.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 Competence protein J (ComJ) NVEALA PF14055.6 GAN05430.1 - 0.055 13.4 0.0 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 NVEALA protein Med26_M PF15694.5 GAN05430.1 - 0.14 12.2 2.3 0.28 11.2 2.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain DUF2967 PF11179.8 GAN05430.1 - 0.44 8.6 6.4 0.71 7.9 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Afi1 PF07792.12 GAN05430.1 - 0.48 10.9 6.3 0.37 11.3 0.5 2.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SMC_N PF02463.19 GAN05430.1 - 1.6 8.1 11.9 3.4 7.0 0.0 3.7 3 1 1 4 4 4 0 RecF/RecN/SMC N terminal domain HLH PF00010.26 GAN05431.1 - 1.3e-06 28.3 4.5 1.5e-06 28.1 2.6 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RP853 PF17542.2 GAN05431.1 - 0.073 12.2 1.0 0.11 11.7 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 Draxin PF15550.6 GAN05431.1 - 0.85 9.4 3.9 1.3 8.8 3.8 1.4 1 1 0 1 1 1 0 Draxin SLX9 PF15341.6 GAN05431.1 - 2.5 8.5 10.8 1.7 9.1 7.7 2.2 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 CK_II_beta PF01214.18 GAN05432.1 - 1.2e-71 240.3 0.1 1.4e-71 240.1 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit F-box-like PF12937.7 GAN05433.1 - 0.0005 19.9 0.2 0.0012 18.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN05433.1 - 0.0013 18.6 0.3 0.0028 17.5 0.3 1.6 1 0 0 1 1 1 1 F-box domain S_2TMBeta PF18153.1 GAN05433.1 - 0.11 12.3 0.8 0.4 10.4 0.9 1.8 2 0 0 2 2 2 0 SMODS-associating 2TM, beta-strand rich effector domain WD40 PF00400.32 GAN05434.1 - 4.8e-06 27.2 3.8 0.0051 17.6 0.0 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 GAN05434.1 - 0.013 14.2 0.0 0.033 12.9 0.0 1.7 2 0 0 2 2 2 0 Nup133 N terminal like CMAS PF02353.20 GAN05435.1 - 9.1e-67 225.2 1.0 1.1e-66 224.9 1.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 GAN05435.1 - 3.8e-12 46.8 0.0 9.4e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05435.1 - 8.3e-12 45.6 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05435.1 - 1.9e-08 34.3 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN05435.1 - 1.4e-07 32.1 0.0 2.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN05435.1 - 6.2e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAN05435.1 - 0.00015 21.4 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 GAN05435.1 - 0.00031 20.3 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAN05435.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 GAN05435.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GAN05435.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Mito_carr PF00153.27 GAN05436.1 - 5.8e-58 192.8 6.4 3.2e-20 71.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 GAN05436.1 - 0.0071 16.5 0.1 0.63 10.2 0.1 2.4 2 0 0 2 2 2 1 PrcB C-terminal Wzz PF02706.15 GAN05436.1 - 0.11 12.8 0.1 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 Chain length determinant protein MtrF PF09472.10 GAN05436.1 - 0.22 11.0 3.0 0.63 9.5 0.2 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) peroxidase PF00141.23 GAN05437.1 - 9.1e-47 159.7 0.0 1.3e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Ysc84 PF04366.12 GAN05438.1 - 2.6e-42 143.6 0.1 4.6e-42 142.8 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 GAN05438.1 - 3.4e-14 52.2 0.0 9.4e-14 50.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN05438.1 - 1.6e-11 43.7 0.0 3.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAN05438.1 - 1.3e-10 41.0 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SCP2 PF02036.17 GAN05439.1 - 7.9e-10 39.1 0.2 2.1e-09 37.8 0.1 1.7 2 0 0 2 2 2 1 SCP-2 sterol transfer family ACOX PF01756.19 GAN05440.1 - 3.1e-51 173.5 0.0 5.8e-51 172.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAN05440.1 - 2.7e-26 92.6 3.2 7.1e-26 91.2 3.2 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAN05440.1 - 2.5e-13 50.1 0.0 5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAN05440.1 - 1e-05 25.8 0.1 0.00016 22.0 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Z1 PF10593.9 GAN05440.1 - 0.1 12.1 0.1 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 Z1 domain RHD3 PF05879.12 GAN05441.1 - 8.2e-253 840.9 21.7 2e-218 727.2 15.8 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 GAN05441.1 - 2.7e-06 27.5 1.4 1e-05 25.6 0.0 2.6 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 GAN05441.1 - 4.3e-06 26.8 0.1 1.6e-05 25.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 GAN05441.1 - 2.4e-05 23.8 0.2 7.1e-05 22.2 0.2 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 GAN05441.1 - 0.024 14.9 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ELM2 PF01448.24 GAN05441.1 - 0.027 15.2 0.2 3.1 8.6 0.2 3.0 2 0 0 2 2 2 0 ELM2 domain RsgA_GTPase PF03193.16 GAN05441.1 - 0.035 14.0 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase RmlD_sub_bind PF04321.17 GAN05442.1 - 5.9e-65 219.2 0.0 7.9e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAN05442.1 - 2.4e-22 79.6 0.0 3.5e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAN05442.1 - 2.9e-08 33.5 0.0 7.8e-08 32.1 0.0 1.6 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAN05442.1 - 6.7e-08 32.0 0.0 2.9e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAN05442.1 - 4.3e-07 29.4 0.0 1.8e-05 24.0 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 GAN05442.1 - 5e-07 29.0 0.0 6.9e-07 28.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GAN05442.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Rrf2 PF02082.20 GAN05442.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DUF2615 PF11027.8 GAN05443.1 - 0.15 12.2 2.0 0.23 11.6 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) LMBR1 PF04791.16 GAN05444.1 - 1.5e-85 288.0 24.5 4.2e-85 286.6 17.1 3.1 2 1 1 3 3 3 2 LMBR1-like membrane protein ADH_zinc_N_2 PF13602.6 GAN05445.1 - 1.6e-14 55.1 0.0 3.4e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAN05445.1 - 4.9e-13 49.2 0.1 1.1e-12 48.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN05445.1 - 1.3e-11 44.3 0.2 2.1e-10 40.4 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 GAN05445.1 - 3.3e-05 23.8 0.1 4.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) TSP9 PF11493.8 GAN05445.1 - 0.0013 19.4 0.1 0.0097 16.6 0.0 2.3 2 0 0 2 2 2 1 Thylakoid soluble phosphoprotein TSP9 Semialdhyde_dh PF01118.24 GAN05445.1 - 0.0038 17.7 0.0 0.01 16.3 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Biotin_lipoyl PF00364.22 GAN05445.1 - 0.29 11.0 2.7 0.18 11.7 0.3 2.0 2 0 0 2 2 2 0 Biotin-requiring enzyme PUF PF00806.19 GAN05446.1 - 5.6e-55 180.0 14.3 8.8e-08 31.4 0.1 8.5 7 1 1 8 8 8 8 Pumilio-family RNA binding repeat DUF4734 PF15881.5 GAN05446.1 - 1.7 8.9 4.8 1.7 8.8 0.1 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4734) RRP36 PF06102.12 GAN05447.1 - 5.2 7.0 16.6 0.098 12.6 3.9 2.5 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 TFIIA_gamma_N PF02268.16 GAN05449.1 - 1.3e-25 89.1 0.1 1.8e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 GAN05449.1 - 3.7e-24 84.6 1.3 5.1e-24 84.2 1.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit HLH PF00010.26 GAN05450.1 - 1.2e-06 28.4 0.5 3.5e-06 26.9 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BRCT_3 PF18428.1 GAN05450.1 - 0.068 13.3 0.1 0.8 9.8 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain HECT PF00632.25 GAN05451.1 - 3.9e-97 325.4 0.1 6e-97 324.8 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 GAN05451.1 - 4.8e-36 122.5 19.5 1.4e-12 47.5 0.9 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 GAN05451.1 - 2.9e-21 75.7 0.6 7.9e-21 74.3 0.6 1.8 1 1 0 1 1 1 1 C2 domain PCI PF01399.27 GAN05452.1 - 2.1e-12 47.5 0.2 6.1e-12 46.0 0.2 1.8 1 0 0 1 1 1 1 PCI domain TPR_16 PF13432.6 GAN05452.1 - 0.026 15.2 0.0 0.41 11.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF745 PF05335.13 GAN05452.1 - 0.047 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TPR_2 PF07719.17 GAN05452.1 - 0.22 11.7 5.1 1.1 9.5 0.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN05452.1 - 0.34 10.8 2.3 9 6.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CLP1_P PF16575.5 GAN05453.1 - 1e-51 175.4 0.8 3.6e-51 173.6 0.8 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 GAN05453.1 - 2.5e-37 127.0 0.1 4.9e-37 126.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 GAN05453.1 - 1.2e-36 125.6 0.0 2.6e-36 124.6 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 GAN05453.1 - 0.003 17.6 0.1 0.047 13.8 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATPase PF06745.13 GAN05453.1 - 0.011 15.1 0.2 0.57 9.5 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_35 PF14516.6 GAN05453.1 - 0.026 13.3 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.6 GAN05453.1 - 0.029 14.4 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAN05453.1 - 0.046 13.5 0.1 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAN05453.1 - 0.064 13.0 0.1 0.087 12.6 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Roc PF08477.13 GAN05453.1 - 0.092 13.0 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 GAN05453.1 - 0.093 12.3 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TniB PF05621.11 GAN05453.1 - 0.14 11.5 0.1 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 GAN05453.1 - 0.18 12.2 0.2 0.39 11.1 0.2 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-grasp PF02222.22 GAN05454.1 - 1.9e-65 219.6 0.1 4.5e-65 218.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.20 GAN05454.1 - 2.4e-62 208.9 3.2 2.4e-62 208.9 3.2 1.9 2 0 0 2 2 2 1 AIR carboxylase PurK_C PF17769.1 GAN05454.1 - 2.2e-19 68.8 0.1 4.7e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 GAN05454.1 - 4.6e-07 29.5 0.1 8.2e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 GAN05454.1 - 2.1e-06 27.5 0.2 1.3e-05 24.8 0.2 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 GAN05454.1 - 9.7e-06 25.5 0.4 1.8e-05 24.6 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 GAN05454.1 - 0.00012 21.6 0.6 0.0011 18.4 0.1 2.4 1 1 0 2 2 2 1 ATP-grasp domain AlaDh_PNT_C PF01262.21 GAN05454.1 - 0.00015 21.2 2.6 0.00018 20.8 0.9 2.1 2 1 1 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAN05454.1 - 0.0016 18.4 0.3 0.0047 16.8 0.3 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.14 GAN05454.1 - 0.0086 16.1 0.2 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 GAN05454.1 - 0.013 14.9 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 GAN05454.1 - 0.089 13.3 0.3 0.47 11.0 0.3 2.3 1 1 0 1 1 1 0 XdhC Rossmann domain Erv26 PF04148.13 GAN05455.1 - 9.8e-15 54.9 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Diphthami_syn_2 PF01902.17 GAN05456.1 - 5.3e-33 114.4 0.0 1.3e-32 113.1 0.0 1.6 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GAN05456.1 - 4.1e-29 101.0 0.5 8.2e-14 51.7 0.0 4.2 3 1 1 4 4 4 3 Endoribonuclease L-PSP Poty_PP PF08440.10 GAN05456.1 - 0.026 13.6 0.2 0.047 12.8 0.2 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein Gti1_Pac2 PF09729.9 GAN05458.1 - 4e-57 193.2 0.0 4e-57 193.2 0.0 2.8 2 2 0 2 2 2 1 Gti1/Pac2 family Melibiase PF02065.18 GAN05459.1 - 1.4e-102 343.2 0.0 1.9e-102 342.8 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 GAN05459.1 - 1.9e-50 171.8 0.0 2.5e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 GAN05459.1 - 2.2e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 GAN05459.1 - 2.9e-06 26.6 0.2 6.1e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Melibiase_2 PF16499.5 GAN05459.1 - 6e-06 25.6 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Glyco_hydro_31 PF01055.26 GAN05459.1 - 7.9e-06 25.3 0.1 1.2e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Ins134_P3_kin_N PF17927.1 GAN05459.1 - 0.09 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Sugar_tr PF00083.24 GAN05461.1 - 2.2e-36 125.7 31.5 8e-34 117.3 31.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN05461.1 - 1.1e-16 60.7 59.6 8.3e-15 54.6 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Androgen_recep PF02166.16 GAN05462.1 - 0.43 9.4 20.9 1 8.1 11.5 2.2 2 0 0 2 2 2 0 Androgen receptor HgmA PF04209.13 GAN05462.1 - 2.2 6.9 5.6 7 5.2 2.4 2.2 2 0 0 2 2 2 0 homogentisate 1,2-dioxygenase DUF4770 PF15994.5 GAN05462.1 - 3 8.0 12.7 6.1 7.0 5.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) GTA_holin_3TM PF11351.8 GAN05462.1 - 3 8.4 7.6 11 6.5 1.3 2.3 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Roughex PF06020.11 GAN05462.1 - 6.7 5.7 11.0 2.6 7.1 3.3 2.4 2 0 0 2 2 2 0 Drosophila roughex protein Malic_M PF03949.15 GAN05463.1 - 2.2e-95 318.8 0.0 2.9e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAN05463.1 - 1.5e-71 239.9 0.0 3e-71 239.0 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SelB-wing_2 PF09106.11 GAN05463.1 - 0.041 14.1 0.0 29 5.0 0.0 3.6 3 0 0 3 3 3 0 Elongation factor SelB, winged helix Peptidase_M16_M PF16187.5 GAN05464.1 - 5.3e-103 344.1 1.2 1.2e-102 343.0 1.2 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAN05464.1 - 6.5e-42 143.0 0.2 7.6e-41 139.6 0.1 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAN05464.1 - 1.9e-36 125.8 0.2 1.6e-20 73.9 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Tet_JBP PF12851.7 GAN05464.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_2 PF13532.6 GAN05465.1 - 2.1e-34 119.4 0.0 3.1e-33 115.6 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Yip1 PF04893.17 GAN05465.1 - 9.8e-08 31.9 14.0 1.9e-07 31.0 14.0 1.5 1 0 0 1 1 1 1 Yip1 domain Transferase PF02458.15 GAN05467.1 - 1.9e-56 191.6 0.0 2.4e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family Lipase_GDSL_2 PF13472.6 GAN05468.1 - 3.5e-24 86.2 0.0 8.6e-24 84.9 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAN05468.1 - 3.1e-21 76.3 0.0 4.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cpn60_TCP1 PF00118.24 GAN05469.1 - 2.3e-147 491.6 9.0 1.4e-145 485.7 9.0 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 GAN05469.1 - 0.0028 17.2 0.1 0.0074 15.8 0.1 1.7 1 0 0 1 1 1 1 EAL domain Nitro_FeMo-Co PF02579.17 GAN05469.1 - 0.0029 17.9 0.5 0.042 14.2 0.1 2.9 2 1 0 3 3 3 1 Dinitrogenase iron-molybdenum cofactor CRS1_YhbY PF01985.21 GAN05469.1 - 0.082 13.1 1.6 1.5 9.1 0.2 2.8 2 2 0 2 2 2 0 CRS1 / YhbY (CRM) domain SET PF00856.28 GAN05470.1 - 7.7e-19 68.7 1.0 7.7e-19 68.7 1.0 3.3 2 2 0 2 2 2 1 SET domain N-SET PF11764.8 GAN05470.1 - 8.7e-10 39.0 4.1 1.7e-07 31.5 0.3 4.3 3 1 1 4 4 4 2 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 GAN05470.1 - 3.7e-09 36.3 0.0 1.1e-07 31.5 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 GAN05470.1 - 0.0054 16.4 0.2 0.032 13.9 0.0 2.4 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated Peptidase_S8 PF00082.22 GAN05471.1 - 6.4e-47 160.2 11.5 1e-46 159.6 11.5 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 GAN05471.1 - 6.7e-16 59.0 3.3 6.7e-16 59.0 3.3 2.1 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 GAN05471.1 - 4.5e-15 55.4 3.3 4.5e-15 55.4 3.3 2.0 2 0 0 2 2 2 1 PA domain DUF11 PF01345.18 GAN05471.1 - 0.00084 19.6 4.0 0.00088 19.5 2.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF11 ASH PF15780.5 GAN05471.1 - 0.039 14.1 0.7 3.7 7.8 0.1 2.5 1 1 1 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 GAN05471.1 - 0.055 13.3 1.7 1.4 8.8 0.4 2.5 2 0 0 2 2 2 0 MSP (Major sperm protein) domain DUF916 PF06030.12 GAN05471.1 - 0.089 12.9 2.3 0.39 10.8 1.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) CotJB PF12652.7 GAN05471.1 - 0.43 10.8 1.3 0.57 10.4 0.2 1.7 2 0 0 2 2 2 0 CotJB protein LNS2 PF08235.13 GAN05473.1 - 1.8e-103 344.9 0.0 2.6e-103 344.4 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 GAN05473.1 - 5.8e-41 138.6 0.0 1.1e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 GAN05473.1 - 8.4e-18 64.4 0.0 3.3e-17 62.5 0.0 2.1 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain HSP70 PF00012.20 GAN05474.1 - 4.9e-257 854.0 12.1 5.6e-257 853.8 12.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN05474.1 - 1.6e-17 63.3 0.3 1.2e-15 57.1 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 GAN05474.1 - 0.00014 22.2 4.1 0.25 11.8 0.0 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 GAN05474.1 - 0.012 14.9 1.0 0.2 10.9 0.2 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 GAN05474.1 - 0.051 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4449 PF14613.6 GAN05474.1 - 0.19 11.8 3.9 2.3 8.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4449) UPF0242 PF06785.11 GAN05474.1 - 6.2 6.9 7.3 0.88 9.6 2.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Actin PF00022.19 GAN05475.1 - 2.1e-43 148.5 0.0 4.2e-43 147.5 0.0 1.4 1 1 0 1 1 1 1 Actin DnaJ_C PF01556.18 GAN05476.1 - 4.5e-34 117.7 0.2 6.3e-34 117.2 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN05476.1 - 1.1e-23 83.1 3.1 2.4e-23 82.0 3.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAN05476.1 - 1e-14 54.6 13.3 1e-14 54.6 13.3 2.2 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 GAN05476.1 - 0.00023 21.1 11.2 0.017 15.1 0.2 2.7 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein Alanine_zipper PF11839.8 GAN05476.1 - 0.79 10.1 14.7 1.7 9.1 14.7 1.6 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein RPE65 PF03055.15 GAN05477.1 - 4e-98 329.6 0.5 4.6e-98 329.4 0.5 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Ydc2-catalyt PF09159.10 GAN05478.1 - 1.2e-18 67.9 0.2 2.4e-13 50.5 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 GAN05478.1 - 7.1e-06 25.7 0.0 1.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.13 GAN05478.1 - 0.053 13.6 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 Poxvirus A22 protein Amidohydro_3 PF07969.11 GAN05479.1 - 4e-18 66.1 1.8 4.2e-12 46.3 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 GAN05479.1 - 3.4e-16 59.5 0.0 1.8e-12 47.2 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Ras PF00071.22 GAN05480.1 - 7.3e-29 100.4 0.0 9.6e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN05480.1 - 3.3e-08 33.8 0.0 7.4e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN05480.1 - 0.034 13.6 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family FA_desaturase PF00487.24 GAN05481.1 - 4.6e-44 151.2 9.4 7.9e-44 150.4 9.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAN05481.1 - 1.7e-11 44.1 0.2 4e-11 42.9 0.2 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2207 PF09972.9 GAN05481.1 - 0.079 11.7 0.7 0.65 8.7 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TRAP-gamma PF07074.12 GAN05481.1 - 0.14 11.7 1.5 0.36 10.4 1.5 1.6 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SH3_1 PF00018.28 GAN05482.1 - 2.3e-10 39.9 0.0 3.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN05482.1 - 3.2e-09 36.3 0.0 5.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAN05482.1 - 1.2e-07 31.5 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 GAN05482.1 - 0.012 15.6 0.2 0.049 13.7 0.2 1.9 1 1 0 1 1 1 0 SH3 domain SH3_4 PF06347.13 GAN05482.1 - 0.096 12.5 0.1 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial SH3 domain E3_UFM1_ligase PF09743.9 GAN05483.1 - 2.3e-29 102.9 9.2 7.2e-29 101.2 0.5 2.8 3 1 1 4 4 4 2 E3 UFM1-protein ligase 1 Glt_symporter PF03616.14 GAN05483.1 - 0.13 10.9 0.2 0.28 9.8 0.2 1.5 1 0 0 1 1 1 0 Sodium/glutamate symporter F-box-like PF12937.7 GAN05484.1 - 0.0021 17.9 0.0 0.0058 16.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like GDPD PF03009.17 GAN05485.1 - 1.2e-28 100.6 0.0 2.6e-28 99.5 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 GAN05485.1 - 0.00047 20.5 1.3 0.0013 19.1 1.3 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ANAPC5 PF12862.7 GAN05488.1 - 2.2e-17 62.9 14.2 6.3e-15 55.0 1.2 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 GAN05488.1 - 1.1e-08 34.9 1.3 1.1e-08 34.9 1.3 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 GAN05488.1 - 5.8e-05 23.3 0.6 0.44 10.9 0.0 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN05488.1 - 0.076 13.5 0.8 2.9 8.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NUC173 PF08161.12 GAN05489.1 - 3.4e-67 226.1 4.3 6.4e-64 215.4 0.2 5.1 5 1 0 5 5 5 2 NUC173 domain Abhydrolase_9_N PF15420.6 GAN05489.1 - 0.025 14.6 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus NUC130_3NT PF08158.12 GAN05489.1 - 0.095 13.0 0.0 9 6.7 0.0 3.5 3 0 0 3 3 3 0 NUC130/3NT domain BLOC1S3 PF15753.5 GAN05489.1 - 0.42 10.7 3.3 1.2 9.3 3.3 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 zf-H2C2_2 PF13465.6 GAN05490.1 - 3.2e-07 30.5 7.6 1.2e-06 28.7 0.1 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 GAN05490.1 - 0.0029 18.0 18.1 0.045 14.2 0.2 3.8 3 1 0 3 3 3 2 Zinc finger, C2H2 type Coilin_N PF15862.5 GAN05490.1 - 0.0071 16.2 0.0 8.9 6.1 2.2 2.3 1 1 1 2 2 2 2 Coilin N-terminus zf-C2H2_8 PF15909.5 GAN05490.1 - 0.038 14.3 1.9 0.14 12.4 0.1 2.6 1 1 0 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAN05490.1 - 0.065 13.9 21.6 0.081 13.6 2.6 4.3 4 1 1 5 5 5 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAN05490.1 - 0.14 13.1 0.2 0.14 13.1 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4611 PF15387.6 GAN05490.1 - 0.23 11.7 3.2 0.61 10.3 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-C2H2_6 PF13912.6 GAN05490.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf_ZIC PF18366.1 GAN05490.1 - 1.2 9.3 10.3 9.2 6.5 0.0 3.5 2 2 1 3 3 3 0 Zic proteins zinc finger domain Cyt_c_ox_IV PF12270.8 GAN05491.1 - 0.00031 20.9 0.1 0.0004 20.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4051 PF13260.6 GAN05491.1 - 0.00069 19.3 0.5 0.00098 18.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4051) CcmH PF03918.14 GAN05491.1 - 0.2 10.9 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein WBP-1 PF11669.8 GAN05491.1 - 0.88 10.2 3.3 1.6 9.4 2.4 1.8 1 1 1 2 2 2 0 WW domain-binding protein 1 SKG6 PF08693.10 GAN05491.1 - 4.1 6.9 5.6 7.1 6.1 5.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain tRNA_m1G_MT PF01746.21 GAN05492.1 - 1.2e-21 77.4 0.3 3.7e-21 75.7 0.3 1.8 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF2052 PF09747.9 GAN05492.1 - 0.46 10.6 14.3 0.071 13.2 5.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PI3K_P85_iSH2 PF16454.5 GAN05493.1 - 0.039 13.6 2.1 0.044 13.4 0.7 1.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FliD_N PF02465.18 GAN05493.1 - 0.23 12.2 5.5 0.98 10.2 1.0 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ebp2 PF05890.12 GAN05494.1 - 1e-81 274.4 26.9 1e-81 274.4 26.9 1.6 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Pkinase PF00069.25 GAN05495.1 - 2.1e-70 237.1 0.0 2.7e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05495.1 - 4e-34 118.1 0.0 5.1e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05495.1 - 8.2e-06 25.3 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1132 PF06575.12 GAN05495.1 - 0.08 13.3 0.5 0.19 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) Haspin_kinase PF12330.8 GAN05495.1 - 0.12 11.3 0.2 0.22 10.4 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain GTP_EFTU PF00009.27 GAN05496.1 - 1.5e-46 158.4 0.0 2.7e-46 157.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GAN05496.1 - 8.8e-38 129.6 16.0 1.5e-37 128.8 16.0 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 GAN05496.1 - 5e-23 81.2 0.0 1.3e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAN05496.1 - 1e-22 80.0 0.0 2.9e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAN05496.1 - 3.1e-10 40.3 0.1 7.4e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAN05496.1 - 6.9e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAN05496.1 - 6e-05 23.1 0.3 0.00014 21.9 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAN05496.1 - 0.0083 15.7 0.3 0.031 13.9 0.3 1.9 1 1 0 1 1 1 1 Ras family Septin PF00735.18 GAN05496.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 GAN05496.1 - 0.45 10.6 5.6 1.4 8.9 0.0 3.1 2 1 0 3 3 3 0 Dynamin family HLH PF00010.26 GAN05497.1 - 7.9e-12 45.0 5.0 8.2e-12 44.9 2.2 2.5 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain PhoU_div PF01865.16 GAN05497.1 - 0.01 15.1 0.3 0.018 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 YabA PF06156.13 GAN05497.1 - 2.9 8.6 13.1 0.15 12.7 4.0 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Cgr1 PF03879.14 GAN05498.1 - 2.1e-25 89.2 33.8 2.6e-25 88.9 33.8 1.0 1 0 0 1 1 1 1 Cgr1 family AAA_13 PF13166.6 GAN05498.1 - 0.15 10.7 10.2 0.17 10.5 10.2 1.0 1 0 0 1 1 1 0 AAA domain DUF936 PF06075.12 GAN05498.1 - 0.53 9.1 14.9 0.58 9.0 14.9 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Exonuc_VII_L PF02601.15 GAN05498.1 - 3.7 7.0 11.4 4.1 6.9 11.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit VSG_B PF13206.6 GAN05498.1 - 3.9 6.6 16.1 4.6 6.4 16.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Vfa1 PF08432.10 GAN05498.1 - 5.8 7.2 16.9 6.3 7.1 16.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ada3 PF10198.9 GAN05499.1 - 2e-30 105.6 1.6 2e-30 105.6 1.6 2.4 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 PIG-F PF06699.11 GAN05500.1 - 3.4e-39 134.9 8.8 4.1e-39 134.6 8.8 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2530 PF10745.9 GAN05500.1 - 1.1 9.5 7.4 0.83 9.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) zf-C2H2_4 PF13894.6 GAN05501.1 - 0.00021 21.9 1.2 0.00068 20.3 1.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN05501.1 - 0.0013 19.1 1.4 0.0013 19.1 1.4 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAN05501.1 - 0.0025 18.1 0.1 0.0051 17.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAN05501.1 - 0.0086 16.1 0.2 0.018 15.0 0.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAN05501.1 - 0.01 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 GAN05501.1 - 0.019 15.4 3.4 4.5 7.8 0.9 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 GAN05501.1 - 0.096 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type mRNA_cap_enzyme PF01331.19 GAN05502.1 - 2.7e-37 128.5 0.1 8.2e-35 120.4 0.1 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GAN05502.1 - 2e-19 70.2 0.0 6.2e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain SET PF00856.28 GAN05503.1 - 1.4e-23 84.1 3.9 6.6e-23 81.9 0.3 2.6 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 GAN05503.1 - 5.4e-15 56.0 3.8 5.4e-15 56.0 3.8 2.5 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 GAN05503.1 - 1e-07 31.7 0.4 2.4e-07 30.6 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AWS PF17907.1 GAN05503.1 - 0.0087 16.1 3.6 0.023 14.7 3.6 1.7 1 0 0 1 1 1 1 AWS domain Mucin PF01456.17 GAN05503.1 - 5 7.1 16.3 8.9 6.3 16.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein AICARFT_IMPCHas PF01808.18 GAN05504.1 - 5.2e-94 315.0 0.5 7.9e-94 314.4 0.2 1.5 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 GAN05504.1 - 2.1e-25 88.8 0.0 8.8e-25 86.7 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain EF-hand_1 PF00036.32 GAN05505.1 - 3.7e-25 85.5 17.3 4.3e-08 32.2 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN05505.1 - 2.3e-21 76.0 7.6 1.1e-12 48.2 1.5 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN05505.1 - 4e-19 66.9 10.9 5.2e-05 22.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAN05505.1 - 1.8e-16 58.8 18.4 1.4e-06 27.5 0.4 4.6 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 GAN05505.1 - 1.7e-12 47.0 14.0 1e-05 25.3 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAN05505.1 - 1.2e-06 28.8 0.1 0.012 16.0 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAN05505.1 - 3e-05 23.9 9.4 0.0034 17.3 0.8 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAN05505.1 - 0.0098 16.2 0.2 1.2 9.5 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain DUF4815 PF16075.5 GAN05505.1 - 0.054 11.8 0.1 0.076 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) Dockerin_1 PF00404.18 GAN05505.1 - 0.14 12.4 2.6 0.89 9.8 0.6 2.7 1 1 1 2 2 2 0 Dockerin type I domain Nse4-Nse3_bdg PF15412.6 GAN05505.1 - 0.6 10.3 5.3 6.1 7.0 0.6 3.5 3 1 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE DASH_Dad4 PF08650.10 GAN05507.1 - 3.3e-16 59.0 1.7 8.2e-16 57.7 1.7 1.7 1 0 0 1 1 1 1 DASH complex subunit Dad4 Myb_DNA-binding PF00249.31 GAN05507.1 - 8.9e-07 29.0 0.3 2e-06 27.9 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN05507.1 - 4.2e-05 23.7 2.2 4.2e-05 23.7 2.2 2.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 GAN05507.1 - 0.00087 19.3 0.4 0.0028 17.7 0.1 2.0 2 0 0 2 2 2 1 SLIDE DASH_Dad1 PF08649.10 GAN05507.1 - 0.13 12.4 3.6 0.2 11.9 0.5 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF1775 PF07987.11 GAN05508.1 - 1.9e-27 96.4 0.7 3.1e-27 95.7 0.7 1.4 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) Psu PF07455.11 GAN05509.1 - 0.091 12.3 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) AMP-binding PF00501.28 GAN05510.1 - 3e-98 329.2 0.0 3.6e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN05510.1 - 2.2e-13 51.0 0.2 5.5e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 GAN05511.1 - 7.1e-39 133.7 24.2 5.8e-23 81.4 11.4 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAN05511.1 - 5.3e-11 42.0 9.3 3.4e-07 29.5 0.2 3.2 1 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 GAN05511.1 - 1.3e-09 37.4 15.3 8.7e-08 31.4 2.3 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 GAN05511.1 - 1.1e-06 27.3 4.8 0.014 13.7 0.0 3.3 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 GAN05511.1 - 1.5e-05 24.5 4.8 0.0062 15.9 0.7 2.6 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 GAN05511.1 - 0.00013 20.6 19.3 0.00025 19.7 3.2 3.0 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.13 GAN05511.1 - 0.0035 15.8 1.0 0.0035 15.8 1.0 2.5 3 0 0 3 3 3 1 Transmembrane secretion effector LacY_symp PF01306.19 GAN05511.1 - 0.023 13.5 9.6 0.52 9.0 4.8 3.0 2 1 0 2 2 2 0 LacY proton/sugar symporter Pam17 PF08566.10 GAN05511.1 - 0.15 11.9 2.1 0.25 11.2 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 UPF0086 PF01868.16 GAN05512.1 - 3.4e-28 97.4 0.0 6.4e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ras PF00071.22 GAN05513.1 - 3.2e-55 186.1 0.0 3.7e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN05513.1 - 5.6e-21 75.0 0.0 7.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN05513.1 - 6.2e-08 32.3 0.0 1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAN05513.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAN05513.1 - 0.13 12.2 0.0 0.59 10.0 0.0 2.0 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 GAN05513.1 - 0.18 11.2 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MFS_1 PF07690.16 GAN05514.1 - 5e-45 154.0 45.6 7.4e-42 143.5 38.5 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN05514.1 - 6.9e-15 54.5 13.1 1.1e-14 53.8 13.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAN05514.1 - 1.9e-14 53.4 3.5 1.9e-14 53.4 3.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAN05514.1 - 0.00053 19.0 9.4 0.00053 19.0 9.4 2.5 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 GAN05514.1 - 3.6 5.8 23.4 13 4.0 17.9 3.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 GAN05515.1 - 1.2e-63 215.0 0.0 3.1e-63 213.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05515.1 - 4.8e-34 117.8 0.0 8.7e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 GAN05515.1 - 3.5e-19 68.4 25.5 1.3e-10 41.0 10.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 GAN05515.1 - 7e-08 33.1 0.5 3.5e-07 30.8 0.5 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 GAN05515.1 - 1.9e-07 31.1 24.6 1.2e-05 25.3 5.7 3.7 4 0 0 4 4 4 2 Hr1 repeat C2 PF00168.30 GAN05515.1 - 4.5e-05 23.7 0.0 9.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pkinase_fungal PF17667.1 GAN05515.1 - 0.0025 16.7 0.5 0.0025 16.7 0.5 2.6 2 2 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAN05515.1 - 0.41 9.5 10.4 0.0065 15.4 2.8 2.0 2 1 0 2 2 2 0 Haspin like kinase domain PHD_2 PF13831.6 GAN05515.1 - 6.8 6.3 12.8 1.5 8.4 2.3 2.6 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 GAN05515.1 - 9 6.7 19.5 8.5 6.8 6.5 2.8 2 0 0 2 2 2 0 C1 domain HSP70 PF00012.20 GAN05516.1 - 5.6e-07 28.1 0.0 7.8e-06 24.4 0.0 2.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN05516.1 - 0.00054 18.9 0.0 0.086 11.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.20 GAN05517.1 - 0.00013 20.3 0.0 0.0002 19.7 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN05517.1 - 0.028 13.3 0.0 0.1 11.4 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein DnaJ PF00226.31 GAN05518.1 - 6.7e-23 80.6 1.7 8.6e-20 70.6 0.9 2.8 2 0 0 2 2 2 2 DnaJ domain SUIM_assoc PF16619.5 GAN05518.1 - 0.0098 15.9 1.9 0.0098 15.9 1.9 3.4 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 GAN05518.1 - 0.08 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MDM10 PF12519.8 GAN05518.1 - 4.5 6.0 14.3 6.9 5.4 0.1 2.7 2 1 1 3 3 3 0 Mitochondrial distribution and morphology protein 10 Spt20 PF12090.8 GAN05518.1 - 9.6 5.7 19.3 3.4 7.2 5.4 2.3 2 0 0 2 2 2 0 Spt20 family eIF-6 PF01912.18 GAN05519.1 - 1.7e-83 278.8 0.4 1.7e-83 278.8 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family Ribosomal_L27A PF00828.19 GAN05520.1 - 1.7e-20 74.0 1.1 2.4e-20 73.5 1.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_S9 PF00380.19 GAN05521.1 - 5.6e-30 104.3 0.1 6.3e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Aromatic_hydrox PF11723.8 GAN05522.1 - 0.054 13.0 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase GPI-anchored PF10342.9 GAN05523.1 - 3.3e-11 43.8 1.9 7.4e-11 42.7 1.9 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glucan_synthase PF02364.15 GAN05524.1 - 0 1175.5 0.5 0 1174.6 0.5 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GAN05524.1 - 3e-32 111.7 2.6 4.6e-30 104.6 2.6 2.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1499 PF07386.11 GAN05524.1 - 0.13 12.8 0.4 8.3 7.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1499) DUF4342 PF14242.6 GAN05524.1 - 2.9 7.9 4.2 0.72 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) HIT PF01230.23 GAN05525.1 - 3.1e-23 82.4 0.1 6.6e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAN05525.1 - 9.3e-09 35.8 0.0 2.2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAN05525.1 - 0.00013 21.9 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 LEA_2 PF03168.13 GAN05526.1 - 3.2e-06 27.6 0.0 5.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF2897 PF11446.8 GAN05526.1 - 0.013 15.4 1.1 0.025 14.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF4668 PF15701.5 GAN05526.1 - 0.12 12.2 2.4 0.2 11.4 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) SNARE PF05739.19 GAN05526.1 - 7.8 6.6 7.2 18 5.5 7.2 1.6 1 0 0 1 1 1 0 SNARE domain Coq4 PF05019.13 GAN05527.1 - 6.5e-95 316.6 0.0 7.7e-95 316.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 XylR_N PF06505.11 GAN05527.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Activator of aromatic catabolism RPAP2_Rtr1 PF04181.13 GAN05528.1 - 7.6e-21 74.2 1.8 7.6e-21 74.2 1.8 2.3 2 0 0 2 2 2 1 Rtr1/RPAP2 family CCD PF07860.11 GAN05528.1 - 0.5 10.4 7.2 0.73 9.9 1.0 3.3 3 0 0 3 3 3 0 WisP family C-Terminal Region Med3 PF11593.8 GAN05529.1 - 0.001 18.3 1.5 0.0017 17.6 1.5 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal ComK PF06338.11 GAN05529.1 - 0.0077 15.9 2.9 0.043 13.5 1.4 2.1 2 0 0 2 2 2 1 ComK protein Cadherin_C_2 PF16492.5 GAN05529.1 - 0.37 11.6 3.8 1.2 9.9 3.8 1.9 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Proton_antipo_C PF01010.19 GAN05529.1 - 1.7 8.2 6.0 0.93 9.1 0.6 2.1 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus CK_II_beta PF01214.18 GAN05530.1 - 1.6e-70 236.7 0.3 4.9e-70 235.1 0.3 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Dynactin_p62 PF05502.13 GAN05530.1 - 3.3 6.4 5.6 7 5.3 5.6 1.4 1 0 0 1 1 1 0 Dynactin p62 family bZIP_2 PF07716.15 GAN05531.1 - 4e-09 36.4 7.7 4e-09 36.4 7.7 1.7 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 GAN05531.1 - 6.7e-09 35.7 8.2 1.1e-08 35.0 8.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor ADIP PF11559.8 GAN05531.1 - 0.0022 18.1 6.9 0.0031 17.6 6.9 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 GAN05531.1 - 0.012 16.1 3.7 0.017 15.6 3.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region RNA_pol_Rpb1_6 PF04992.14 GAN05531.1 - 0.012 15.4 0.7 0.016 15.0 0.7 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 DUF2400 PF09674.10 GAN05531.1 - 0.015 15.3 1.0 0.018 15.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Mto2_bdg PF12808.7 GAN05531.1 - 0.019 15.3 2.1 0.019 15.3 2.1 1.8 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_Maf PF03131.17 GAN05531.1 - 0.028 15.0 8.1 0.043 14.3 8.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor EMP24_GP25L PF01105.24 GAN05531.1 - 0.036 14.0 1.1 0.047 13.6 1.1 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ZapB PF06005.12 GAN05531.1 - 0.062 13.7 5.4 0.092 13.2 5.2 1.4 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 GAN05531.1 - 0.13 12.9 4.4 0.22 12.2 4.4 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Pacifastin_I PF05375.13 GAN05532.1 - 2.5e-21 75.1 21.7 3e-11 42.8 10.6 2.1 1 1 1 2 2 2 2 Pacifastin inhibitor (LCMII) TILa PF12714.7 GAN05532.1 - 0.0038 17.2 18.5 0.024 14.6 4.5 2.3 1 1 1 2 2 2 2 TILa domain HHH_7 PF14635.6 GAN05534.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-RVT PF13966.6 GAN05534.1 - 0.18 12.5 1.5 0.45 11.3 0.1 2.2 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase IATP PF04568.12 GAN05535.1 - 1.2e-06 28.9 1.8 1.5e-06 28.6 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Spc7 PF08317.11 GAN05535.1 - 0.00042 19.3 1.0 0.00043 19.3 1.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.12 GAN05535.1 - 0.021 15.4 2.2 0.047 14.3 1.7 1.8 1 1 1 2 2 2 0 SlyX QueC PF06508.13 GAN05535.1 - 0.024 14.1 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF2188 PF09954.9 GAN05535.1 - 0.036 14.2 1.0 0.061 13.5 0.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Flu_M1_C PF08289.11 GAN05535.1 - 0.072 13.3 0.3 0.088 13.0 0.3 1.1 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Atg14 PF10186.9 GAN05535.1 - 0.096 11.7 3.9 0.1 11.6 3.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 GAN05535.1 - 0.31 11.5 3.7 0.36 11.3 3.7 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Bap31_Bap29_C PF18035.1 GAN05535.1 - 0.65 10.0 7.8 1 9.4 7.8 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain ANTH PF07651.16 GAN05536.1 - 3.9e-76 255.7 0.1 3.9e-76 255.7 0.1 3.7 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 GAN05536.1 - 5e-53 179.4 11.7 5e-53 179.4 11.7 6.0 3 2 3 6 6 6 1 I/LWEQ domain DUF2534 PF10749.9 GAN05537.1 - 0.3 11.3 3.5 0.13 12.4 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) CNH PF00780.22 GAN05538.1 - 4.6e-45 154.3 0.0 9.7e-45 153.3 0.0 1.6 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAN05538.1 - 6.8e-34 117.7 1.9 6.8e-34 117.7 1.9 3.5 4 1 0 4 4 4 1 RhoGEF domain PH_5 PF15405.6 GAN05538.1 - 1.1e-20 74.1 0.0 1.1e-20 74.1 0.0 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain SUIM_assoc PF16619.5 GAN05538.1 - 0.22 11.6 17.6 11 6.2 5.0 4.4 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 ERM PF00769.19 GAN05539.1 - 0.0024 17.7 26.1 0.084 12.7 2.2 2.3 2 0 0 2 2 2 2 Ezrin/radixin/moesin family DivIC PF04977.15 GAN05539.1 - 0.0044 16.8 1.8 0.0044 16.8 1.8 3.5 2 1 2 4 4 4 1 Septum formation initiator TolA_bind_tri PF16331.5 GAN05539.1 - 0.0052 16.8 21.7 0.11 12.6 2.7 3.4 2 1 1 3 3 3 2 TolA binding protein trimerisation MscS_porin PF12795.7 GAN05539.1 - 0.039 13.5 22.4 0.069 12.7 12.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 GAN05539.1 - 0.076 13.0 13.3 0.19 11.8 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 GAN05539.1 - 0.1 12.8 26.3 0.4 10.9 3.5 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 GAN05539.1 - 0.13 12.8 33.3 3.4 8.2 4.1 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Spc24 PF08286.11 GAN05539.1 - 0.14 12.4 19.7 1.6 9.0 0.5 3.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Fez1 PF06818.15 GAN05539.1 - 0.24 11.8 21.9 2.2 8.7 1.7 2.2 2 0 0 2 2 2 0 Fez1 Lebercilin PF15619.6 GAN05539.1 - 0.25 11.0 27.3 2.8 7.6 14.1 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 GAN05539.1 - 0.28 11.6 15.9 7.2 7.1 0.1 3.1 2 1 1 3 3 3 0 Type III cell invasion protein SipB DUF4201 PF13870.6 GAN05539.1 - 0.48 10.1 24.5 0.53 10.0 11.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Rootletin PF15035.6 GAN05539.1 - 0.55 10.2 23.4 5.6 7.0 1.7 2.9 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Mod_r PF07200.13 GAN05539.1 - 0.56 10.3 32.1 0.13 12.4 7.2 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 GAN05539.1 - 0.59 10.6 27.6 0.91 10.0 6.1 3.5 2 1 1 3 3 3 0 Cell division protein ZapB YabA PF06156.13 GAN05539.1 - 0.6 10.8 20.6 3.3 8.4 2.9 3.2 2 1 1 3 3 3 0 Initiation control protein YabA EzrA PF06160.12 GAN05539.1 - 0.68 8.0 23.0 0.35 9.0 12.4 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Prefoldin PF02996.17 GAN05539.1 - 0.73 9.8 20.9 5.2 7.0 0.8 3.8 2 1 1 3 3 3 0 Prefoldin subunit DUF4200 PF13863.6 GAN05539.1 - 0.85 10.0 22.7 0.87 10.0 3.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) GIT_CC PF16559.5 GAN05539.1 - 0.95 9.4 16.7 0.72 9.8 0.4 4.3 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Uso1_p115_C PF04871.13 GAN05539.1 - 1.1 9.7 25.8 1.4 9.3 7.5 3.5 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.20 GAN05539.1 - 1.6 8.0 25.2 0.2 11.0 14.0 2.2 2 0 0 2 2 2 0 Tropomyosin Paralemmin PF03285.15 GAN05539.1 - 1.8 8.1 15.1 0.46 10.0 1.1 2.4 2 1 0 2 2 2 0 Paralemmin Laminin_II PF06009.12 GAN05539.1 - 2.4 8.2 15.0 6.8 6.7 7.0 2.5 2 1 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 GAN05539.1 - 2.5 8.6 10.8 8.1 6.9 0.7 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) LPP PF04728.13 GAN05539.1 - 2.8 8.4 11.9 5.2 7.5 0.7 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 GAN05539.1 - 2.9 7.2 17.9 63 2.8 17.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 GAN05539.1 - 3.1 7.6 20.9 3.8 7.3 9.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) GrpE PF01025.19 GAN05539.1 - 4 7.1 21.3 1.5 8.5 4.2 2.6 2 1 1 3 3 3 0 GrpE Jnk-SapK_ap_N PF09744.9 GAN05539.1 - 5.6 7.2 31.6 6.3 7.0 15.3 2.9 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DLP_helical PF18709.1 GAN05539.1 - 6.3 5.9 17.9 0.22 10.7 2.8 2.9 2 1 1 3 3 3 0 Dynamin-like helical domain FapA PF03961.13 GAN05539.1 - 8.3 4.9 14.6 0.92 8.0 4.9 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A CsbD PF05532.12 GAN05540.1 - 3.4e-11 42.9 6.6 5.6e-11 42.2 6.6 1.4 1 0 0 1 1 1 1 CsbD-like Apolipoprotein PF01442.18 GAN05540.1 - 0.036 13.9 0.3 0.045 13.6 0.3 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain zf-C2H2_jaz PF12171.8 GAN05541.1 - 0.0068 16.7 47.3 0.057 13.7 0.8 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN05541.1 - 0.0085 16.5 41.0 0.6 10.6 0.5 5.8 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 GAN05541.1 - 0.07 13.9 18.0 1.5 9.7 0.1 3.8 2 1 2 4 4 4 0 zinc-ribbon family DUF4685 PF15737.5 GAN05541.1 - 0.1 13.0 0.3 0.1 13.0 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) zf-C2H2_2 PF12756.7 GAN05541.1 - 0.13 12.6 32.2 0.36 11.2 5.9 4.8 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN05541.1 - 0.16 12.9 53.9 0.41 11.6 5.9 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger zf-UBP PF02148.19 GAN05541.1 - 0.17 12.2 12.6 0.76 10.1 2.8 4.1 3 1 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein DUF629 PF04780.12 GAN05541.1 - 1.7 7.1 35.6 2.7 6.4 0.2 6.6 7 0 0 7 7 7 0 Protein of unknown function (DUF629) Serine_protease PF18405.1 GAN05542.1 - 0.00077 18.7 0.0 0.00098 18.4 0.0 1.2 1 0 0 1 1 1 1 Gammaproteobacterial serine protease WD40 PF00400.32 GAN05543.1 - 5.1e-46 153.7 30.4 1e-08 35.7 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05543.1 - 3.2e-17 62.6 9.8 0.0016 18.7 0.8 6.1 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 GAN05543.1 - 0.15 10.0 10.4 1.1 7.1 1.3 3.0 1 1 0 1 1 1 0 IKI3 family Coatomer_WDAD PF04053.14 GAN05543.1 - 0.52 9.3 5.2 0.59 9.1 1.0 2.7 2 1 1 3 3 3 0 Coatomer WD associated region DUF2387 PF09526.10 GAN05543.1 - 9 6.5 7.4 21 5.3 0.1 3.8 4 0 0 4 4 4 0 Probable metal-binding protein (DUF2387) GHMP_kinases_N PF00288.26 GAN05544.1 - 0.8 10.0 5.1 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain Transposase_21 PF02992.14 GAN05545.1 - 5.5e-07 29.0 0.0 7.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Utp12 PF04003.12 GAN05546.1 - 2.5e-17 63.1 1.1 3.6e-17 62.6 1.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Pox_Ag35 PF03286.14 GAN05546.1 - 0.09 12.6 10.7 0.53 10.1 8.9 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Rad51 PF08423.11 GAN05547.1 - 2.5e-51 174.4 0.1 3e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAN05547.1 - 2.4e-10 40.3 0.0 3.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAN05547.1 - 1.4e-08 34.4 2.3 1.1e-07 31.4 0.8 2.7 1 1 1 2 2 2 1 KaiC RecA PF00154.21 GAN05547.1 - 1.3e-07 31.4 0.9 4.2e-07 29.7 0.9 1.8 1 1 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 GAN05547.1 - 2e-07 30.6 2.3 1.8e-05 24.2 2.3 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain NACHT PF05729.12 GAN05547.1 - 0.0043 17.0 0.1 0.0088 16.0 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 GAN05547.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAN05547.1 - 0.049 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 GAN05548.1 - 1.5e-43 149.1 17.3 1.7e-43 148.9 16.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily EOS1 PF12326.8 GAN05548.1 - 0.017 15.0 0.1 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 N-glycosylation protein ECF_trnsprt PF12822.7 GAN05548.1 - 9.3 6.3 19.9 0.26 11.4 7.2 2.9 2 1 0 2 2 2 0 ECF transporter, substrate-specific component Sporozoite_P67 PF05642.11 GAN05550.1 - 0.0047 15.1 4.2 0.0073 14.5 4.2 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Trehalase PF01204.18 GAN05551.1 - 1.1e-177 592.0 4.7 1.3e-177 591.7 4.7 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 GAN05551.1 - 2.1e-14 52.9 0.2 4.7e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Asp PF00026.23 GAN05552.1 - 4.8e-29 101.8 0.0 1.2e-14 54.5 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic aspartyl protease Kelch_3 PF13415.6 GAN05552.1 - 5.8e-08 32.8 12.8 0.011 16.0 0.0 6.8 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_4 PF13418.6 GAN05552.1 - 5.6e-07 29.5 6.6 0.087 12.8 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN05552.1 - 7e-07 29.1 2.3 0.011 15.7 0.0 5.0 5 0 0 5 5 5 2 Kelch motif TAXi_N PF14543.6 GAN05552.1 - 6.4e-06 26.5 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Kelch_2 PF07646.15 GAN05552.1 - 0.0028 17.6 3.9 2.3 8.3 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 GAN05552.1 - 0.2 11.3 10.5 6.4 6.4 0.0 5.9 6 1 0 6 6 6 0 Kelch motif rRNA_proc-arch PF13234.6 GAN05553.1 - 3.1e-81 273.2 0.6 7.2e-81 272.1 0.6 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GAN05553.1 - 1.1e-55 187.7 1.3 1.1e-55 187.7 1.3 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 GAN05553.1 - 3.7e-19 69.2 0.0 3.4e-18 66.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN05553.1 - 1.1e-08 35.3 0.0 1.2e-07 32.1 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN05553.1 - 1.2e-05 25.3 0.0 4.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 GAN05553.1 - 0.01 14.9 0.1 0.068 12.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 GAN05553.1 - 0.04 13.8 1.9 0.28 11.0 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CobU PF02283.16 GAN05553.1 - 0.12 11.9 0.5 0.41 10.2 0.1 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4407 PF14362.6 GAN05553.1 - 0.77 9.1 3.7 5.4 6.3 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) ArgoMid PF16487.5 GAN05553.1 - 1.9 8.8 5.2 21 5.4 0.3 3.4 4 0 0 4 4 4 0 Mid domain of argonaute YlqD PF11068.8 GAN05553.1 - 7.6 6.9 10.3 0.2 12.1 0.2 3.2 4 0 0 4 4 4 0 YlqD protein MutS_V PF00488.21 GAN05554.1 - 9e-58 195.4 0.0 2.5e-57 193.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAN05554.1 - 2.8e-32 112.5 1.5 6.2e-32 111.4 1.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAN05554.1 - 6.5e-13 48.8 0.2 6.5e-13 48.8 0.2 2.2 3 0 0 3 3 3 1 MutS family domain IV ATPase_2 PF01637.18 GAN05554.1 - 0.011 15.6 0.1 0.52 10.2 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MutS_II PF05188.17 GAN05554.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 MutS domain II CobU PF02283.16 GAN05554.1 - 0.14 11.7 0.0 15 5.1 0.0 2.8 2 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_29 PF13555.6 GAN05554.1 - 0.15 11.9 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAN05554.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.0 3 1 0 3 3 3 0 AAA domain WD40 PF00400.32 GAN05555.1 - 1.5e-29 101.6 0.2 1.1e-09 38.7 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05555.1 - 1.4e-10 41.4 0.1 0.00012 22.3 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN05555.1 - 2.6e-05 24.2 0.0 0.15 11.9 0.0 2.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A bZIP_1 PF00170.21 GAN05555.1 - 0.0032 17.5 0.9 0.006 16.7 0.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Nup160 PF11715.8 GAN05555.1 - 0.0057 15.4 0.2 0.42 9.2 0.0 2.9 2 1 0 3 3 3 1 Nucleoporin Nup120/160 betaPIX_CC PF16523.5 GAN05555.1 - 0.026 14.4 0.6 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 betaPIX coiled coil DivIC PF04977.15 GAN05555.1 - 0.032 14.0 0.9 0.056 13.2 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator WD40_like PF17005.5 GAN05555.1 - 0.056 12.8 0.0 3 7.1 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain Cnn_1N PF07989.11 GAN05555.1 - 0.071 13.3 0.4 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Ge1_WD40 PF16529.5 GAN05555.1 - 0.089 11.7 0.0 2.8 6.8 0.0 2.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4597 PF15366.6 GAN05556.1 - 1.3 8.8 5.7 1.4 8.7 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) RabGAP-TBC PF00566.18 GAN05557.1 - 3.9e-21 75.7 4.0 8.3e-21 74.6 4.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Cnd3 PF12719.7 GAN05558.1 - 9.2e-73 245.0 8.1 1.1e-71 241.4 2.4 3.9 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAN05558.1 - 5.2e-09 36.4 0.4 0.0045 17.4 0.1 4.6 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAN05558.1 - 7.3e-05 22.9 8.3 0.031 14.3 0.0 5.0 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAN05558.1 - 0.00032 20.7 5.8 12 6.5 0.0 6.7 8 0 0 8 8 8 2 HEAT repeat BUD22 PF09073.10 GAN05558.1 - 0.089 12.1 51.6 0.07 12.5 3.9 2.6 3 0 0 3 3 3 0 BUD22 GST_N PF02798.20 GAN05559.1 - 4.7e-13 49.3 0.0 9.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAN05559.1 - 3.8e-11 43.1 1.2 6e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAN05559.1 - 1.3e-07 31.8 0.1 3.3e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAN05559.1 - 5.4e-07 29.9 0.3 1e-06 29.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAN05559.1 - 2.5e-06 27.4 0.0 5.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAN05559.1 - 0.00079 19.2 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAN05559.1 - 0.0022 18.2 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EF1G PF00647.19 GAN05559.1 - 0.15 12.1 0.5 0.43 10.6 0.2 2.0 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain EF1G PF00647.19 GAN05560.1 - 1.6e-15 57.0 0.1 2.8e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain PAS_9 PF13426.7 GAN05561.1 - 9e-30 103.0 0.0 2.9e-14 53.2 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 GAN05561.1 - 2.5e-21 75.7 0.0 3.3e-15 56.1 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 GAN05561.1 - 6.3e-18 64.8 0.0 2.7e-08 33.8 0.0 4.1 4 1 0 4 4 4 3 PAS fold PAS_11 PF14598.6 GAN05561.1 - 1.7e-12 47.4 0.0 1.1e-08 35.2 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 GAN05561.1 - 5.5e-12 45.9 0.0 5.7e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_2 PF08446.11 GAN05561.1 - 0.00017 22.3 0.0 1.7 9.4 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 GAN05561.1 - 0.00018 21.5 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain DPPIV_N PF00930.21 GAN05562.1 - 1.5e-49 168.7 8.5 1.5e-49 168.7 8.5 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAN05562.1 - 1.7e-45 155.1 0.3 4.8e-45 153.6 0.3 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAN05562.1 - 4.3e-06 26.5 0.1 2e-05 24.3 0.1 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 GAN05562.1 - 8.5e-06 25.6 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 GAN05562.1 - 0.00019 21.2 0.6 0.0013 18.4 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN05562.1 - 0.0013 19.4 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 GAN05562.1 - 0.041 13.4 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.12 GAN05562.1 - 0.089 11.4 0.0 0.29 9.8 0.0 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 GAN05562.1 - 0.09 12.0 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 GAN05562.1 - 0.11 12.0 0.0 0.48 10.0 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Myb_DNA-bind_4 PF13837.6 GAN05564.1 - 0.0015 18.8 0.2 0.0015 18.8 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Abhydrolase_3 PF07859.13 GAN05565.1 - 2e-28 99.7 0.0 3.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN05565.1 - 1.5e-16 60.3 0.0 2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAN05565.1 - 0.00066 19.2 0.0 0.0013 18.2 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family SE PF08491.10 GAN05566.1 - 1.1e-110 369.1 0.0 1.4e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GAN05566.1 - 6.8e-16 58.4 0.0 9.2e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAN05566.1 - 1.5e-08 34.6 0.0 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 GAN05566.1 - 8.1e-05 21.9 0.2 0.00032 19.9 0.2 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAN05566.1 - 0.00025 20.3 0.6 0.35 9.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAN05566.1 - 0.0004 19.7 0.1 0.0026 17.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.19 GAN05566.1 - 0.0014 18.1 0.1 0.41 10.0 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_oxidored PF12831.7 GAN05566.1 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN05566.1 - 0.002 18.3 0.2 0.004 17.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAN05566.1 - 0.023 13.6 0.1 0.96 8.2 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAN05566.1 - 0.094 11.9 0.1 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 GAN05566.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor SAPS PF04499.15 GAN05567.1 - 2e-103 346.8 14.4 2.8e-57 194.6 9.1 3.5 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein EppA_BapA PF07268.11 GAN05567.1 - 0.045 13.7 0.7 0.72 9.8 0.0 2.5 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) RisS_PPD PF16524.5 GAN05567.1 - 0.14 12.4 0.4 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Aa_trans PF01490.18 GAN05568.1 - 4.8e-63 213.3 21.8 5.8e-63 213.0 21.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1218 PF06749.12 GAN05568.1 - 1.8 9.1 5.9 5.9 7.5 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1218) Saf_2TM PF18303.1 GAN05568.1 - 6.2 6.4 11.0 1.7 8.2 2.1 2.9 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain bZIP_1 PF00170.21 GAN05569.1 - 4.6e-11 42.6 8.5 4.6e-11 42.6 8.5 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAN05569.1 - 5.3e-07 29.6 7.4 1.5e-06 28.2 7.4 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 GAN05569.1 - 2.9e-05 24.4 2.6 2.9e-05 24.4 2.6 4.0 3 2 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 GAN05569.1 - 8.2e-05 22.9 3.5 8.2e-05 22.9 3.5 2.7 2 2 0 2 2 2 1 Aft1 HRA domain HALZ PF02183.18 GAN05569.1 - 0.015 15.5 1.9 0.027 14.7 1.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.17 GAN05569.1 - 0.016 15.7 4.3 0.016 15.7 4.3 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor zf-C2H2 PF00096.26 GAN05570.1 - 0.0018 18.6 14.2 0.088 13.3 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 GAN05570.1 - 0.0021 17.8 3.3 0.0021 17.8 3.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 GAN05570.1 - 0.0064 16.9 12.6 0.0084 16.5 0.7 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN05570.1 - 0.086 13.7 14.3 0.7 10.9 3.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.9 GAN05570.1 - 0.12 12.5 0.6 16 5.7 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 GAN05570.1 - 8.6 6.8 14.8 2 8.8 5.5 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Methyltransf_25 PF13649.6 GAN05571.1 - 2.4e-08 34.5 0.0 1.1e-06 29.2 0.0 3.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05571.1 - 3e-08 34.2 0.5 3.4e-07 30.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05571.1 - 1.7e-06 27.9 0.1 5.7e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN05571.1 - 0.00015 21.6 0.0 0.0083 15.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05571.1 - 0.00066 19.1 0.0 0.0025 17.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CAAX_1 PF15895.5 GAN05571.1 - 0.17 11.8 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 CAAX box cerebral protein 1 TFIIA PF03153.13 GAN05571.1 - 2.3 8.2 13.2 4 7.3 13.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YodL PF14191.6 GAN05571.1 - 9.3 7.2 7.6 39 5.2 0.2 3.7 3 1 1 4 4 4 0 YodL-like Tim17 PF02466.19 GAN05573.1 - 1.2e-14 54.6 0.5 7.4e-14 52.1 0.4 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 GAN05573.1 - 2.4 8.3 5.7 9.2 6.5 2.4 2.4 1 1 0 2 2 2 0 Family of unknown function (DUF5518) Pkinase PF00069.25 GAN05574.1 - 1.4e-72 244.2 0.1 1.2e-71 241.2 0.0 2.5 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05574.1 - 5.8e-34 117.5 0.0 6.4e-32 110.8 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05574.1 - 1.1e-07 31.4 1.4 0.01 15.1 0.8 2.5 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 GAN05574.1 - 0.00047 19.8 1.0 0.00047 19.8 1.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 GAN05574.1 - 0.0066 15.3 0.0 0.0066 15.3 0.0 2.1 2 2 0 2 2 2 1 Fungal protein kinase Polysacc_deac_1 PF01522.21 GAN05574.1 - 0.11 12.4 0.2 0.28 11.1 0.2 1.7 1 0 0 1 1 1 0 Polysaccharide deacetylase FTA2 PF13095.6 GAN05574.1 - 0.13 11.8 2.2 0.74 9.4 0.1 2.7 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DASH_Ask1 PF08655.10 GAN05575.1 - 1.8e-20 72.6 2.1 3.4e-20 71.7 2.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 MbeD_MobD PF04899.12 GAN05575.1 - 0.056 13.6 1.1 0.19 11.9 0.2 2.4 2 0 0 2 2 2 0 MbeD/MobD like Fructosamin_kin PF03881.14 GAN05576.1 - 2.1e-70 237.2 0.0 2.4e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GAN05576.1 - 3.7e-08 33.6 0.1 4.6e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAN05576.1 - 0.064 12.6 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase AAA PF00004.29 GAN05577.1 - 6.9e-43 146.2 0.0 1.3e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN05577.1 - 2.4e-12 46.4 0.1 8.2e-12 44.7 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAN05577.1 - 2e-11 43.7 0.0 4.7e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain NTF2 PF02136.20 GAN05577.1 - 5.2e-07 30.2 0.0 1.1e-05 25.9 0.0 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain AAA_2 PF07724.14 GAN05577.1 - 9.8e-07 29.0 0.0 7.4e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAN05577.1 - 5.9e-06 26.3 0.1 7.5e-05 22.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAN05577.1 - 1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAN05577.1 - 2.9e-05 24.5 0.5 0.005 17.3 0.1 3.2 3 1 1 4 4 2 1 AAA ATPase domain LRR_9 PF14580.6 GAN05577.1 - 0.00016 21.2 0.3 0.00042 19.9 0.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat AAA_7 PF12775.7 GAN05577.1 - 0.00079 19.0 0.0 0.0029 17.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 GAN05577.1 - 0.00099 19.4 0.1 0.01 16.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain RRM_9 PF18444.1 GAN05577.1 - 0.0015 18.3 0.0 0.0044 16.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif DUF815 PF05673.13 GAN05577.1 - 0.0018 17.5 0.0 0.0047 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 GAN05577.1 - 0.0031 17.2 0.2 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAN05577.1 - 0.005 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 GAN05577.1 - 0.0053 16.4 0.1 0.052 13.2 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 GAN05577.1 - 0.006 17.1 0.0 0.023 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 GAN05577.1 - 0.0076 16.3 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 GAN05577.1 - 0.0089 16.1 0.0 0.039 14.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAN05577.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 GAN05577.1 - 0.017 15.5 0.0 0.048 14.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 GAN05577.1 - 0.019 15.2 0.0 0.058 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAN05577.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein LRR_8 PF13855.6 GAN05577.1 - 0.026 14.3 2.1 0.23 11.3 0.5 2.5 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 GAN05577.1 - 0.027 14.9 1.6 0.54 10.8 0.5 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) AAA_3 PF07726.11 GAN05577.1 - 0.031 14.1 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAN05577.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 GAN05577.1 - 0.11 12.4 0.1 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 GAN05577.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CHCH PF06747.13 GAN05578.1 - 5.5e-06 26.4 13.2 6.6e-06 26.1 4.5 2.3 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 GAN05578.1 - 2.7e-05 24.1 11.1 0.0009 19.2 3.1 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 GAN05578.1 - 3.2 8.1 10.3 13 6.2 0.9 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GAN05578.1 - 3.2 7.8 11.4 5.8 7.0 3.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 GAN05578.1 - 3.8 7.3 8.5 0.45 10.3 2.2 2.1 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) SPT6_acidic PF14632.6 GAN05579.1 - 1.9 9.1 15.1 0.38 11.4 10.4 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Peptidase_M24 PF00557.24 GAN05580.1 - 7e-51 172.9 0.0 9.5e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAN05580.1 - 4.6e-15 55.4 0.0 1.6e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain RRF PF01765.19 GAN05581.1 - 3.3e-51 173.4 8.0 3.3e-51 173.4 8.0 1.8 2 0 0 2 2 2 1 Ribosome recycling factor ApoL PF05461.11 GAN05581.1 - 5.3e-05 22.7 4.7 0.0064 15.9 1.5 2.1 2 0 0 2 2 2 2 Apolipoprotein L CENP-Q PF13094.6 GAN05581.1 - 0.009 16.2 1.4 0.009 16.2 1.4 2.5 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit HTH_WhiA PF02650.14 GAN05581.1 - 0.011 16.0 5.0 0.02 15.2 0.1 2.7 2 1 1 3 3 3 0 WhiA C-terminal HTH domain DUF4820 PF16091.5 GAN05581.1 - 0.055 12.8 8.0 1.1 8.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) EF-G-binding_N PF07299.11 GAN05581.1 - 0.075 13.6 1.6 0.075 13.6 1.6 3.2 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal GlutR_dimer PF00745.20 GAN05581.1 - 0.16 12.4 6.6 3.7 8.1 2.0 2.6 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF883 PF05957.13 GAN05581.1 - 0.23 12.1 9.6 0.22 12.2 3.4 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) AcylCoA_dehyd_C PF12186.8 GAN05581.1 - 0.49 10.5 5.9 0.29 11.3 0.9 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Vma12 PF11712.8 GAN05581.1 - 0.63 10.1 7.8 2 8.5 0.7 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP19 PF11022.8 GAN05581.1 - 0.85 10.0 6.3 0.27 11.6 2.8 1.9 2 0 0 2 2 2 0 ATP synthase subunit K KMP11 PF03037.16 GAN05581.1 - 2.2 9.1 11.1 3.2 8.6 0.3 3.0 2 1 0 3 3 3 0 Kinetoplastid membrane protein 11 AIF_C PF14721.6 GAN05581.1 - 8.9 6.7 8.3 5.8 7.3 1.9 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term UDPGP PF01704.18 GAN05582.1 - 2.7e-201 668.6 1.1 3.2e-201 668.4 1.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CRAL_TRIO PF00650.20 GAN05583.1 - 2.3e-31 108.7 0.2 3.5e-31 108.1 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN05583.1 - 0.0051 17.0 1.0 0.0093 16.1 0.2 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Cyclin_N PF00134.23 GAN05584.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN05584.1 - 0.0036 17.7 0.1 0.035 14.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin DPBB_1 PF03330.18 GAN05585.1 - 1.6e-12 47.5 0.1 1.6e-12 47.5 0.1 1.9 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 GAN05585.1 - 1.4e-08 34.6 0.2 1.4e-08 34.6 0.2 2.1 2 0 0 2 2 2 1 Barwin family Presenilin PF01080.17 GAN05585.1 - 0.049 12.4 5.8 0.053 12.3 5.8 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 GAN05585.1 - 0.12 12.4 2.7 0.15 12.1 2.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spem1 PF15670.5 GAN05585.1 - 0.14 11.7 2.8 0.18 11.4 2.8 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Hid1 PF12722.7 GAN05585.1 - 0.28 9.3 5.0 0.3 9.1 5.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Otopetrin PF03189.13 GAN05585.1 - 0.36 9.6 4.2 0.47 9.2 4.2 1.2 1 0 0 1 1 1 0 Otopetrin Endomucin PF07010.12 GAN05585.1 - 0.51 10.3 22.4 0.77 9.7 22.4 1.4 1 1 0 1 1 1 0 Endomucin Conotoxin PF02950.17 GAN05585.1 - 0.53 11.3 6.5 1.4 10.0 4.6 2.6 2 1 0 2 2 1 0 Conotoxin Zip PF02535.22 GAN05585.1 - 0.55 9.4 2.6 0.58 9.3 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Draxin PF15550.6 GAN05585.1 - 0.57 10.0 13.5 0.8 9.5 13.5 1.1 1 0 0 1 1 1 0 Draxin XRN_M PF17846.1 GAN05585.1 - 0.57 9.1 1.8 0.75 8.7 1.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF572 PF04502.13 GAN05585.1 - 0.59 9.7 13.1 0.78 9.3 13.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Miga PF10265.9 GAN05585.1 - 0.92 8.4 7.2 1 8.3 7.2 1.1 1 0 0 1 1 1 0 Mitoguardin Ctr PF04145.15 GAN05585.1 - 1.4 9.6 7.4 2 9.0 7.1 1.5 1 1 0 1 1 1 0 Ctr copper transporter family GRP PF07172.11 GAN05585.1 - 1.6 9.4 8.3 13 6.5 5.1 2.5 1 1 1 2 2 2 0 Glycine rich protein family NPR3 PF03666.13 GAN05585.1 - 1.9 7.2 12.3 2.3 6.9 12.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tmemb_9 PF05434.11 GAN05585.1 - 4.6 7.1 7.2 1.5 8.7 2.3 2.5 2 1 0 2 2 2 0 TMEM9 Apt1 PF10351.9 GAN05585.1 - 4.9 5.9 13.7 5.8 5.7 13.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5427 PF10310.9 GAN05585.1 - 5.5 5.8 13.3 6.4 5.6 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Macoilin PF09726.9 GAN05585.1 - 5.7 5.4 13.7 6.3 5.2 13.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF2500 PF10694.9 GAN05585.1 - 6.3 7.4 7.7 1.5e+02 2.9 7.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) Pannexin_like PF12534.8 GAN05585.1 - 9.9 5.1 8.0 15 4.5 8.0 1.4 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SH3_9 PF14604.6 GAN05586.1 - 1.4e-10 40.9 0.1 2.7e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN05586.1 - 9.7e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN05586.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 GAN05586.1 - 0.006 16.7 3.0 0.015 15.4 3.0 1.5 1 1 0 1 1 1 1 Podoplanin DUF347 PF03988.12 GAN05586.1 - 0.047 13.9 0.9 0.047 13.9 0.9 1.7 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 GAN05586.1 - 0.17 12.7 0.0 0.32 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HMG_box PF00505.19 GAN05587.1 - 5e-24 84.5 1.7 5e-24 84.5 1.7 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN05587.1 - 8.6e-14 51.9 1.3 8.6e-14 51.9 1.3 2.1 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 GAN05587.1 - 0.00051 20.0 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.6 GAN05587.1 - 0.0015 18.5 1.0 0.0015 18.5 1.0 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box 5 Ribosomal_60s PF00428.19 GAN05587.1 - 0.013 16.1 1.2 0.013 16.1 1.2 2.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein Aa_trans PF01490.18 GAN05588.1 - 7.2e-51 173.2 41.9 8.7e-50 169.6 41.9 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_1 PF18181.1 GAN05588.1 - 3.3 7.6 6.1 3.9 7.4 0.0 3.3 3 1 1 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 TB2_DP1_HVA22 PF03134.19 GAN05589.1 - 6.2e-21 74.1 7.3 1.1e-20 73.3 7.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MRP-S34 PF16053.5 GAN05590.1 - 1.5e-12 47.3 0.1 1.8e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Flg_bbr_C PF06429.13 GAN05590.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal NIPSNAP PF07978.13 GAN05591.1 - 6.9e-30 103.3 0.0 6.3e-20 71.3 0.1 2.3 2 0 0 2 2 2 2 NIPSNAP ketoacyl-synt PF00109.26 GAN05592.1 - 8.1e-62 209.1 1.5 1.3e-61 208.4 0.5 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAN05592.1 - 9.4e-37 125.6 0.2 1.6e-36 124.8 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAN05592.1 - 6.2e-06 25.8 0.1 1.4e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN05592.1 - 0.00017 21.2 3.6 0.0069 16.0 0.1 3.6 3 1 1 4 4 4 1 Thiolase, C-terminal domain DNA_pol_delta_4 PF04081.13 GAN05593.1 - 3e-25 89.1 0.1 3.5e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 ORC4_C PF14629.6 GAN05595.1 - 7.6e-41 139.9 0.0 1.8e-40 138.6 0.0 1.5 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 GAN05595.1 - 8.9e-17 62.0 1.7 2.8e-16 60.4 1.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAN05595.1 - 1.6e-10 41.5 0.0 3.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAN05595.1 - 1.4e-07 31.9 0.0 2.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAN05595.1 - 1.6e-07 30.8 0.1 2.5e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 GAN05595.1 - 5.4e-07 29.7 0.1 9.2e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 GAN05595.1 - 9.7e-05 22.0 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 GAN05595.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GAN05595.1 - 0.0014 17.9 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 GAN05595.1 - 0.0026 18.1 0.0 0.0064 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAN05595.1 - 0.0069 16.1 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 GAN05595.1 - 0.01 15.8 0.1 0.032 14.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAN05595.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAN05595.1 - 0.03 14.3 0.4 0.091 12.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 GAN05595.1 - 0.033 13.3 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Y_phosphatase2 PF03162.13 GAN05595.1 - 0.055 13.0 0.2 0.21 11.1 0.0 2.1 3 0 0 3 3 3 0 Tyrosine phosphatase family TrwB_AAD_bind PF10412.9 GAN05595.1 - 0.085 11.8 0.1 0.26 10.2 0.0 1.7 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 GAN05595.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 GAN05595.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 GAN05595.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 GAN05595.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 GAN05595.1 - 0.19 11.4 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SIS PF01380.22 GAN05596.1 - 2.5e-23 82.4 0.0 6.2e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 GAN05596.1 - 9.3e-09 35.6 4.2 1.5e-05 25.3 0.0 4.3 5 0 0 5 5 5 2 CBS domain SIS_2 PF13580.6 GAN05596.1 - 1.1e-06 28.8 0.0 0.0029 17.6 0.0 2.6 1 1 1 2 2 2 2 SIS domain Abhydrolase_3 PF07859.13 GAN05597.1 - 7.2e-35 120.8 0.0 1e-34 120.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN05597.1 - 1.2e-24 86.9 0.0 3.7e-24 85.3 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAN05597.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family BsuBI_PstI_RE PF06616.11 GAN05597.1 - 0.045 13.1 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain COesterase PF00135.28 GAN05597.1 - 0.045 12.6 0.0 3.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Pkinase PF00069.25 GAN05598.1 - 9.2e-70 235.0 0.0 1.3e-69 234.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05598.1 - 5e-46 157.1 0.0 8.7e-46 156.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAN05598.1 - 8.9e-23 80.4 0.1 2.2e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 GAN05598.1 - 1.5e-07 31.0 0.0 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN05598.1 - 1.9e-05 23.6 0.1 3.7e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAN05598.1 - 0.0011 18.0 0.6 0.0026 16.8 0.6 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN05598.1 - 0.034 13.5 0.3 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAN05598.1 - 0.041 13.5 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DSHCT PF08148.12 GAN05598.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 GAN05598.1 - 0.35 10.8 2.8 1.1 9.1 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF2721 PF11026.8 GAN05599.1 - 0.033 14.1 0.2 2.6 8.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Aldo_ket_red PF00248.21 GAN05600.1 - 4e-45 154.2 0.1 3e-44 151.4 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family BLACT_WH PF17778.1 GAN05600.1 - 0.02 14.9 0.2 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain NPV_P10 PF05531.12 GAN05601.1 - 0.0029 18.0 0.9 0.0029 18.0 0.9 2.7 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.8 GAN05601.1 - 0.017 15.4 5.6 0.86 9.9 0.2 2.9 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus TES PF08034.11 GAN05601.1 - 0.19 12.1 0.4 0.19 12.1 0.4 2.4 2 0 0 2 2 2 0 Trematode eggshell synthesis protein Laminin_II PF06009.12 GAN05601.1 - 1.3 9.1 11.3 2.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II RPN1_RPN2_N PF17781.1 GAN05602.1 - 2.7e-120 401.4 1.7 4.6e-120 400.7 1.7 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 GAN05602.1 - 2.4e-32 109.7 24.5 1.1e-06 28.8 0.1 8.8 10 0 0 10 10 10 7 Proteasome/cyclosome repeat RPN1_C PF18051.1 GAN05602.1 - 3.9e-32 110.1 0.1 7.1e-32 109.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 GAN05602.1 - 0.00031 21.1 2.9 1.4 9.4 0.1 4.8 6 2 1 7 7 7 2 HEAT repeats Med12-LCEWAV PF12145.8 GAN05602.1 - 1.2 7.9 6.8 1.8 7.3 6.8 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Med26_C PF15693.5 GAN05602.1 - 1.5 8.9 6.1 2.9 8.0 6.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal CDC45 PF02724.14 GAN05602.1 - 3.3 5.9 8.8 4.7 5.4 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_15 PF01793.16 GAN05603.1 - 6e-115 383.9 5.7 7.9e-115 383.5 5.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 GAN05604.1 - 1e-90 304.3 7.1 1.3e-90 303.9 7.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 GAN05605.1 - 2.4e-99 332.7 17.5 1.4e-61 208.6 14.0 2.1 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase VID27 PF08553.10 GAN05606.1 - 4e-73 246.5 0.7 3.9e-72 243.3 0.7 2.0 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 GAN05606.1 - 4.2e-21 75.6 1.7 4.5e-17 62.4 0.7 3.5 2 1 0 2 2 2 2 VID27 N-terminal region VID27_PH PF17747.1 GAN05606.1 - 1.2e-19 70.6 0.5 4.4e-19 68.8 0.1 2.3 2 0 0 2 2 2 1 VID27 PH-like domain Evr1_Alr PF04777.13 GAN05608.1 - 6.9e-30 103.5 1.0 8.4e-30 103.2 1.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family C1_4 PF07975.12 GAN05608.1 - 0.047 13.9 2.3 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain HSP20 PF00011.21 GAN05609.1 - 1.9e-17 63.3 0.0 3.2e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Taeniidae_ag PF05596.11 GAN05609.1 - 2.2e-09 37.1 0.0 2.7 8.0 0.0 6.1 6 0 0 6 6 6 3 Taeniidae antigen ArsA_HSP20 PF17886.1 GAN05609.1 - 1.1e-06 28.1 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CBM_19 PF03427.13 GAN05609.1 - 9.3e-05 22.3 16.3 1.6 8.8 0.6 6.1 5 2 1 6 6 6 2 Carbohydrate binding domain (family 19) ApoA-II PF04711.13 GAN05609.1 - 0.00095 19.3 0.1 42 4.4 0.0 4.9 5 0 0 5 5 5 0 Apolipoprotein A-II (ApoA-II) Glyco_transf_18 PF15024.6 GAN05609.1 - 0.0022 16.7 0.8 3.6 6.1 0.0 4.1 3 1 2 5 5 5 1 Glycosyltransferase family 18 CS PF04969.16 GAN05609.1 - 0.0075 17.3 0.0 0.012 16.7 0.0 1.3 1 0 0 1 1 1 1 CS domain Proho_convert PF12177.8 GAN05609.1 - 0.86 9.6 3.1 6.6 6.8 0.1 3.4 4 0 0 4 4 4 0 Prohormone convertase enzyme CGGC PF08821.11 GAN05609.1 - 0.94 9.7 6.5 31 4.8 0.1 4.4 2 1 1 5 5 5 0 CGGC domain Yeast_MT PF11403.8 GAN05609.1 - 2.8 8.6 23.5 40 4.9 0.0 7.8 8 0 0 8 8 8 0 Yeast metallothionein adh_short_C2 PF13561.6 GAN05610.1 - 4.7e-54 183.4 3.7 6.3e-54 183.0 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN05610.1 - 4e-44 150.4 1.1 5e-44 150.1 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN05610.1 - 1e-14 54.9 0.6 1.5e-14 54.3 0.6 1.1 1 0 0 1 1 1 1 KR domain Ysc84 PF04366.12 GAN05610.1 - 0.0039 16.9 0.4 0.053 13.3 0.1 2.3 2 1 0 2 2 2 1 Las17-binding protein actin regulator Sacchrp_dh_NADP PF03435.18 GAN05610.1 - 0.005 17.1 0.1 0.012 15.9 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 GAN05610.1 - 0.059 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sec23_trunk PF04811.15 GAN05611.1 - 4.9e-60 203.1 0.0 8.3e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAN05611.1 - 5.5e-15 55.9 0.0 1.8e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAN05611.1 - 6.8e-15 54.8 2.5 2e-14 53.4 2.5 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 GAN05611.1 - 9.7e-14 51.0 0.2 2.1e-13 50.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 GAN05611.1 - 2.8e-08 33.5 0.0 7.7e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Fer2_3 PF13085.6 GAN05612.1 - 1.6e-32 111.7 0.1 2.6e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAN05612.1 - 3.2e-09 37.2 7.9 3.2e-09 37.2 7.9 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAN05612.1 - 4.7e-07 30.2 9.4 4.7e-07 30.2 9.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAN05612.1 - 1e-06 28.7 4.1 1e-06 28.7 4.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAN05612.1 - 0.0019 18.7 5.9 0.0019 18.7 5.9 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAN05612.1 - 0.0041 17.0 3.3 0.006 16.5 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.8 GAN05612.1 - 0.039 14.5 0.2 0.091 13.3 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_18 PF13746.6 GAN05612.1 - 0.41 10.8 4.8 0.83 9.9 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAN05612.1 - 0.55 10.4 14.1 0.26 11.5 9.1 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain HATPase_c PF02518.26 GAN05613.1 - 3.5e-25 88.7 0.4 1.5e-24 86.7 0.3 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 GAN05613.1 - 3.6e-23 81.7 0.2 2.2e-15 56.7 0.1 2.8 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 GAN05613.1 - 1e-18 67.1 0.1 2.2e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 GAN05613.1 - 3.1e-17 62.8 0.0 1.1e-16 60.9 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 GAN05613.1 - 3.8e-16 59.3 0.0 1.4e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 GAN05613.1 - 3.7e-11 43.0 0.0 6e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 GAN05613.1 - 1.2e-10 41.6 0.0 1.1e-07 32.0 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 GAN05613.1 - 0.00076 19.4 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 PAS domain Aminotran_3 PF00202.21 GAN05614.1 - 3.5e-119 398.1 0.0 4.3e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAN05614.1 - 0.01 15.0 0.0 0.042 13.0 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II Aldo_ket_red PF00248.21 GAN05615.1 - 1.3e-77 260.9 0.1 1.5e-77 260.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CBF PF03914.17 GAN05618.1 - 6.7e-31 107.6 2.5 6.7e-31 107.6 2.5 2.1 2 1 0 2 2 2 1 CBF/Mak21 family SPT6_acidic PF14632.6 GAN05618.1 - 0.11 13.1 5.1 2.3 8.8 1.0 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Stealth_CR2 PF11380.8 GAN05618.1 - 0.16 12.2 1.4 2.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Stealth protein CR2, conserved region 2 DUF3510 PF12022.8 GAN05618.1 - 1.1 9.6 5.5 0.43 11.0 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Velvet PF11754.8 GAN05619.1 - 4.1e-45 154.7 7.0 3.3e-33 115.7 1.3 3.9 2 2 1 3 3 3 2 Velvet factor MMR_HSR1 PF01926.23 GAN05620.1 - 5e-21 74.9 0.2 1.2e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN05620.1 - 8.2e-08 32.3 0.4 0.0031 17.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 GAN05620.1 - 1.8e-06 28.1 3.5 0.038 14.0 0.6 3.4 2 1 1 3 3 3 3 Dynamin family FeoB_N PF02421.18 GAN05620.1 - 5.3e-06 26.0 0.2 8.2e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 GAN05620.1 - 7.4e-05 22.4 0.4 0.00012 21.7 0.4 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN05620.1 - 8e-05 22.9 0.1 0.0002 21.6 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAN05620.1 - 9.3e-05 22.0 2.2 0.0013 18.3 2.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 GAN05620.1 - 0.0011 18.3 2.3 0.27 10.5 2.3 2.6 1 1 0 1 1 1 1 Septin AIG1 PF04548.16 GAN05620.1 - 0.0017 17.7 0.1 0.0032 16.8 0.1 1.5 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 GAN05620.1 - 0.0018 18.1 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAN05620.1 - 0.0085 15.5 0.0 0.023 14.1 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MULE PF10551.9 GAN05620.1 - 0.057 13.8 0.1 1.5 9.3 0.0 2.4 1 1 1 2 2 2 0 MULE transposase domain MOZ_SAS PF01853.18 GAN05623.1 - 1.9e-81 272.0 0.2 3e-81 271.4 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAN05623.1 - 5.4e-19 67.5 2.6 5.4e-19 67.5 2.6 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 GAN05623.1 - 0.004 17.6 0.0 0.0087 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4423 PF14394.6 GAN05623.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) DNA_pol_E_B PF04042.16 GAN05624.1 - 1.5e-44 151.9 0.1 2.4e-44 151.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GAN05624.1 - 3.7e-37 127.3 0.0 6.1e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain PS_Dcarbxylase PF02666.15 GAN05625.1 - 1.5e-71 240.1 0.0 2.3e-70 236.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 GAN05625.1 - 0.055 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 MNLL subunit E_raikovi_mat PF06360.11 GAN05627.1 - 1.3 9.5 6.6 2.5 8.6 6.6 1.4 1 0 0 1 1 1 0 Euplotes raikovi mating pheromone adh_short PF00106.25 GAN05628.1 - 1.8e-37 128.7 0.2 2.6e-37 128.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN05628.1 - 3.6e-28 98.7 0.1 4.4e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN05628.1 - 3.5e-10 40.1 0.0 7.9e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAN05628.1 - 9.2e-08 32.2 0.1 1.5e-07 31.5 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAN05628.1 - 5e-05 22.9 0.1 6.5e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAN05628.1 - 0.002 17.7 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 GAN05628.1 - 0.036 13.4 0.1 0.093 12.1 0.1 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 GAN05628.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 GAN05628.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 GAN05629.1 - 6.7e-38 130.1 0.3 1.1e-37 129.4 0.3 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN05629.1 - 1e-30 107.0 0.0 1.3e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN05629.1 - 2.2e-09 37.5 0.0 3.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAN05629.1 - 2.9e-06 26.9 0.8 5.1e-06 26.1 0.3 1.7 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Fibrillarin PF01269.17 GAN05629.1 - 0.00017 20.8 0.1 0.00031 20.0 0.1 1.4 1 0 0 1 1 1 1 Fibrillarin Epimerase PF01370.21 GAN05629.1 - 0.0032 16.9 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAN05629.1 - 0.0065 16.4 0.0 0.0093 15.9 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 GAN05630.1 - 1.9e-53 180.5 0.0 2.5e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAN05630.1 - 5.3e-33 113.5 0.0 6.1e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 GAN05630.1 - 0.00061 20.2 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 GAN05630.1 - 0.0021 18.6 0.0 0.0042 17.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAN05630.1 - 0.008 16.4 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 GAN05630.1 - 0.074 13.1 0.2 0.21 11.7 0.2 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 GAN05630.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CBFD_NFYB_HMF PF00808.23 GAN05631.1 - 2.4e-15 56.6 0.3 3.9e-15 55.9 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAN05631.1 - 1.6e-11 44.7 0.1 2.9e-11 43.8 0.1 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ASFV_J13L PF05568.11 GAN05631.1 - 0.0042 16.9 3.5 0.029 14.2 0.7 2.2 2 0 0 2 2 2 1 African swine fever virus J13L protein Pex14_N PF04695.13 GAN05631.1 - 8 7.1 22.8 3.6 8.2 11.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH PF00169.29 GAN05632.1 - 1.4e-05 25.5 2.9 1.9e-05 25.1 0.6 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 GAN05632.1 - 0.00018 21.9 1.2 0.00018 21.9 1.2 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Hydrolase_6 PF13344.6 GAN05632.1 - 0.21 11.7 1.1 0.7 10.0 1.1 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Beta_elim_lyase PF01212.21 GAN05633.1 - 3.2e-75 253.2 0.2 4e-75 252.8 0.2 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAN05633.1 - 1.5e-05 24.3 0.1 3.1e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAN05633.1 - 7.6e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-U11-48K PF05253.12 GAN05634.1 - 0.16 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger YtzH PF14165.6 GAN05636.1 - 0.019 15.3 0.3 0.067 13.6 0.0 2.0 2 0 0 2 2 2 0 YtzH-like protein AbiH PF14253.6 GAN05636.1 - 0.097 12.5 1.5 0.16 11.8 1.6 1.3 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH DASH_Spc19 PF08287.11 GAN05637.1 - 9e-22 77.6 11.7 9e-22 77.6 11.7 2.8 2 1 1 3 3 3 1 Spc19 DUF3452 PF11934.8 GAN05637.1 - 0.048 13.2 1.5 8.6 5.9 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3452) VASt PF16016.5 GAN05638.1 - 5.3e-29 101.6 1.6 1.4e-28 100.2 1.6 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 GAN05638.1 - 1.4e-26 93.7 7.9 3.7e-26 92.3 7.9 1.7 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 GAN05638.1 - 7e-09 36.1 0.6 2.1e-08 34.6 0.6 1.9 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 GAN05638.1 - 3.8e-05 23.5 0.0 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 GRAM domain FA_desaturase PF00487.24 GAN05638.1 - 0.00051 20.0 1.3 0.0012 18.8 1.3 1.6 1 0 0 1 1 1 1 Fatty acid desaturase IMD PF08397.11 GAN05638.1 - 0.034 13.5 3.9 0.09 12.1 3.9 1.7 1 1 0 1 1 1 0 IRSp53/MIM homology domain HoxA13_N PF12284.8 GAN05638.1 - 0.065 13.9 0.1 0.065 13.9 0.1 3.4 3 1 0 3 3 3 0 Hox protein A13 N terminal DUF1564 PF07600.11 GAN05638.1 - 0.07 12.8 2.6 0.14 11.9 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) BAR PF03114.18 GAN05638.1 - 0.085 12.5 5.7 0.26 10.9 5.7 1.8 1 0 0 1 1 1 0 BAR domain Tape_meas_lam_C PF09718.10 GAN05638.1 - 0.12 12.5 0.9 0.57 10.4 0.1 2.6 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF5134 PF17197.4 GAN05638.1 - 0.36 10.7 2.0 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) Glutaredoxin PF00462.24 GAN05639.1 - 5.5e-23 80.9 0.1 8.2e-23 80.4 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 GAN05639.1 - 8e-05 23.0 0.3 0.00021 21.7 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 GAN05639.1 - 0.00045 20.6 0.1 0.00078 19.8 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 GAN05639.1 - 0.0033 17.4 0.2 0.012 15.6 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin domain TraF PF13728.6 GAN05639.1 - 0.0044 16.9 0.1 0.0049 16.7 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DSBA PF01323.20 GAN05639.1 - 0.012 15.4 0.2 0.038 13.8 0.1 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_3 PF13417.6 GAN05639.1 - 0.019 15.4 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_S51 PF03575.17 GAN05639.1 - 0.034 13.8 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase family S51 ZnuA PF01297.17 GAN05639.1 - 0.035 13.5 0.1 0.045 13.2 0.1 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Thioredoxin_9 PF14595.6 GAN05639.1 - 0.06 13.1 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.20 GAN05639.1 - 0.074 13.0 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin GST_N_2 PF13409.6 GAN05639.1 - 0.088 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF953 PF06110.11 GAN05639.1 - 0.095 12.3 0.2 0.23 11.1 0.2 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) NiFeSe_Hases PF00374.19 GAN05639.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.3 1 1 0 1 1 1 0 Nickel-dependent hydrogenase Thioredoxin_4 PF13462.6 GAN05639.1 - 0.17 12.0 1.0 7.3 6.7 0.3 2.3 1 1 1 2 2 2 0 Thioredoxin Dynamin_N PF00350.23 GAN05641.1 - 5.1e-18 65.7 3.1 2.4e-17 63.5 0.1 3.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 GAN05641.1 - 4.5e-10 39.6 0.5 1.5e-08 34.7 0.1 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN05641.1 - 2.7e-07 30.3 1.6 9.8e-05 22.0 0.6 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN05641.1 - 0.00024 21.0 1.4 1.1 9.2 0.1 3.4 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 GAN05641.1 - 0.0031 17.1 0.1 0.6 9.7 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 GAN05641.1 - 0.008 15.6 0.3 0.26 10.6 0.0 3.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 GAN05641.1 - 0.0085 15.8 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.13 GAN05641.1 - 0.01 14.9 0.4 0.062 12.4 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 GAN05641.1 - 0.071 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAN05641.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 GAN05641.1 - 0.12 12.6 0.1 2.9 8.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 GAN05641.1 - 0.26 11.7 4.5 4.9 7.5 3.0 3.3 1 1 1 2 2 2 0 AAA ATPase domain PIG-U PF06728.13 GAN05642.1 - 6e-106 354.7 43.3 1.8e-105 353.2 43.3 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 GAN05642.1 - 0.0095 15.7 12.7 0.0095 15.7 12.7 1.7 1 1 0 1 1 1 1 8TM Microsporidial transmembrane domain Med5 PF08689.10 GAN05643.1 - 1.5e-13 49.6 1.1 2.3e-13 48.9 0.1 1.8 2 0 0 2 2 2 1 Mediator complex subunit Med5 Med24_N PF11277.8 GAN05643.1 - 0.00012 20.3 0.5 0.23 9.5 0.0 3.2 3 0 0 3 3 3 3 Mediator complex subunit 24 N-terminal Arrestin_C PF02752.22 GAN05644.1 - 1.9e-13 51.0 1.2 9.8e-09 35.8 0.1 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN05644.1 - 6.5e-09 36.0 0.1 1.2e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PEMT PF04191.13 GAN05645.1 - 4.6e-11 43.1 4.1 4.6e-11 43.1 4.1 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 GAN05645.1 - 6e-11 42.6 1.0 6e-11 42.6 1.0 2.2 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 GAN05645.1 - 0.00056 19.5 5.4 0.00086 18.9 5.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 GAN05645.1 - 0.007 16.4 0.9 0.007 16.4 0.9 1.8 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PRA1 PF03208.19 GAN05645.1 - 0.49 10.0 13.3 0.64 9.6 0.6 2.2 2 0 0 2 2 2 0 PRA1 family protein adh_short PF00106.25 GAN05647.1 - 3.9e-36 124.3 0.1 5.7e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN05647.1 - 1.7e-27 96.5 0.1 2e-27 96.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN05647.1 - 7.4e-10 39.0 0.0 1.9e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAN05647.1 - 1.5e-08 34.8 0.1 1.8e-08 34.5 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAN05647.1 - 3.2e-05 23.5 0.1 4.9e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAN05647.1 - 6.8e-05 22.5 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 GAN05647.1 - 0.0029 17.0 0.2 0.076 12.4 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 GAN05647.1 - 0.033 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 GAN05648.1 - 7.1e-37 126.8 0.4 9.8e-37 126.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN05648.1 - 4.6e-27 95.1 0.2 5.6e-27 94.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN05648.1 - 6.1e-10 39.3 0.1 9.3e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAN05648.1 - 2.9e-09 37.1 0.1 3.5e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAN05648.1 - 4e-05 23.2 0.1 5.4e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAN05648.1 - 4.4e-05 23.0 0.0 0.02 14.3 0.1 2.4 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NmrA PF05368.13 GAN05648.1 - 0.0085 15.7 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 GAN05648.1 - 0.016 14.3 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 GAN05648.1 - 0.043 14.4 0.1 0.096 13.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Na_H_antiport_3 PF07399.11 GAN05648.1 - 0.078 11.8 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative Na+/H+ antiporter adh_short PF00106.25 GAN05649.1 - 4.7e-35 120.8 0.2 6e-35 120.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN05649.1 - 8.4e-27 94.2 0.2 1e-26 93.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN05649.1 - 4.5e-09 36.5 0.1 9.8e-09 35.4 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAN05649.1 - 2.6e-06 27.5 0.1 3.3e-06 27.1 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN05649.1 - 0.0012 18.5 0.2 0.0024 17.5 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 GAN05649.1 - 0.0017 17.8 0.0 0.056 12.8 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 GAN05649.1 - 0.17 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain bZIP_1 PF00170.21 GAN05650.1 - 3.1e-11 43.2 9.8 5.3e-11 42.4 9.3 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN05650.1 - 5.3e-08 32.8 8.5 5.3e-08 32.8 8.5 2.4 2 0 0 2 2 2 1 Basic region leucine zipper GIT_CC PF16559.5 GAN05650.1 - 8.8e-05 22.3 2.0 0.0002 21.1 2.0 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_Maf PF03131.17 GAN05650.1 - 0.00049 20.6 6.1 0.00049 20.6 6.1 1.6 2 0 0 2 2 1 1 bZIP Maf transcription factor DUF2353 PF09789.9 GAN05650.1 - 0.017 14.5 2.8 0.031 13.6 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) YabA PF06156.13 GAN05650.1 - 0.032 14.9 0.2 0.083 13.5 0.2 1.7 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 GAN05650.1 - 0.16 12.3 1.6 1.5 9.2 0.3 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 GAN05650.1 - 0.38 10.6 5.6 0.66 9.8 0.9 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF641 PF04859.12 GAN05650.1 - 0.41 11.0 3.4 0.83 10.0 3.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HALZ PF02183.18 GAN05650.1 - 0.74 10.1 5.1 6.6 7.0 0.2 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper UPF0242 PF06785.11 GAN05650.1 - 1.5 8.9 7.8 0.32 11.1 3.9 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 GAN05650.1 - 1.9 8.7 6.4 0.5 10.5 1.4 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Sulfate_transp PF00916.20 GAN05651.1 - 3.3e-106 355.2 20.9 4.7e-106 354.7 20.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN05651.1 - 5.1e-10 39.0 0.0 9.6e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAN05651.1 - 0.00024 21.4 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN05651.1 - 0.02 15.3 2.7 0.02 15.3 2.7 3.5 2 2 1 3 3 3 0 Molybdate transporter of MFS superfamily Autophagy_act_C PF03987.15 GAN05652.1 - 2.3e-18 66.5 3.9 3.9e-18 65.8 3.9 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain ABC_membrane PF00664.23 GAN05655.1 - 1.4e-52 179.1 27.4 2e-34 119.5 13.9 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN05655.1 - 1.2e-45 155.4 0.0 7.2e-30 104.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN05655.1 - 1.5e-06 27.8 2.0 0.2 11.0 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAN05655.1 - 1e-05 26.1 0.7 0.013 16.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAN05655.1 - 2.4e-05 24.0 2.4 0.21 11.4 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 GAN05655.1 - 5.9e-05 22.2 0.1 0.19 10.6 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 GAN05655.1 - 5.9e-05 22.3 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 GAN05655.1 - 0.00016 21.9 0.2 1.1 9.5 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAN05655.1 - 0.0014 18.3 0.3 0.72 9.4 0.1 2.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 GAN05655.1 - 0.0014 18.7 1.0 0.052 13.6 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain ResIII PF04851.15 GAN05655.1 - 0.0021 18.1 0.1 0.48 10.4 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 GAN05655.1 - 0.012 14.8 0.0 0.11 11.7 0.0 2.5 3 1 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 GAN05655.1 - 0.019 14.7 1.6 0.11 12.2 0.2 2.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 GAN05655.1 - 0.022 14.1 1.3 2 7.7 0.2 2.5 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.9 GAN05655.1 - 0.028 13.7 0.1 0.72 9.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.6 GAN05655.1 - 0.029 14.2 2.2 4.2 7.1 0.3 3.1 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAN05655.1 - 0.074 13.4 3.2 2.8 8.3 0.3 3.1 2 2 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 GAN05655.1 - 0.16 11.5 0.4 17 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 GAN05655.1 - 0.2 11.3 0.3 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 GAN05655.1 - 0.42 10.3 1.5 10 5.8 0.1 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAN05655.1 - 1.1 9.1 3.6 23 4.8 0.0 2.8 3 0 0 3 3 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 GAN05655.1 - 1.9 7.8 4.9 14 4.9 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family Velvet PF11754.8 GAN05657.1 - 2.5e-15 57.1 0.8 3.4e-15 56.7 0.1 1.5 2 0 0 2 2 2 1 Velvet factor DUF2415 PF10313.9 GAN05658.1 - 4.8e-15 55.2 0.3 3.7e-13 49.2 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 GAN05658.1 - 2.7e-08 34.3 4.0 0.051 14.5 0.3 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05658.1 - 5.6e-08 33.0 0.1 0.83 10.0 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAN05658.1 - 0.0071 16.4 0.1 3 7.9 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Lgl_C PF08596.10 GAN05658.1 - 0.031 13.0 0.1 0.076 11.7 0.0 1.7 1 1 1 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal SARS_X4 PF08779.10 GAN05658.1 - 0.085 13.1 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 SARS coronavirus X4 like DUF3857 PF12969.7 GAN05658.1 - 0.12 12.5 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) WD40 PF00400.32 GAN05659.1 - 4.6e-26 90.5 18.8 8.9e-06 26.4 0.5 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05659.1 - 7.6e-12 45.4 1.6 0.0026 18.0 0.2 5.9 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 GAN05659.1 - 0.018 13.1 0.2 0.033 12.2 0.2 1.3 1 0 0 1 1 1 0 IKI3 family Nucleoporin_N PF08801.11 GAN05659.1 - 0.029 13.1 0.0 5 5.8 0.1 3.1 1 1 1 3 3 3 0 Nup133 N terminal like eIF2A PF08662.11 GAN05659.1 - 0.091 12.6 0.3 0.46 10.3 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 GAN05660.1 - 3.2e-20 72.4 11.4 8.8e-17 61.1 2.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.22 GAN05661.1 - 2.6e-15 56.1 0.4 3.8e-15 55.5 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 GAN05661.1 - 0.0074 16.1 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4549) muHD PF10291.9 GAN05662.1 - 1.4e-24 87.0 0.0 2.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 GAN05662.1 - 1.1e-11 44.9 1.3 2.6e-11 43.6 0.0 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain CHZ PF09649.10 GAN05663.1 - 1.8e-11 43.3 0.0 1.8e-11 43.3 0.0 2.1 2 0 0 2 2 1 1 Histone chaperone domain CHZ BSP_II PF05432.11 GAN05663.1 - 0.00088 19.1 19.9 0.0011 18.7 19.9 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF4604 PF15377.6 GAN05663.1 - 0.0099 16.3 27.3 0.013 15.9 27.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2052 PF09747.9 GAN05663.1 - 0.018 15.2 18.3 0.024 14.8 18.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PNISR PF15996.5 GAN05663.1 - 0.19 12.0 27.0 0.25 11.6 27.0 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DNA_pol_phi PF04931.13 GAN05663.1 - 0.98 7.4 25.1 1.2 7.1 25.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 GAN05663.1 - 1.5 9.3 31.0 1.2 9.6 13.2 2.7 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 GAN05663.1 - 2.1 6.3 22.1 2.6 6.0 22.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 GAN05663.1 - 2.6 6.7 19.6 3 6.5 19.6 1.1 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 GAN05663.1 - 2.8 8.2 12.8 4.2 7.6 12.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 GAN05663.1 - 3.6 5.8 25.5 4.5 5.4 25.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 GAN05663.1 - 4.8 5.6 23.2 5.3 5.5 23.2 1.0 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 GAN05663.1 - 4.8 6.9 21.8 6.9 6.4 21.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SPATIAL PF15256.6 GAN05663.1 - 7.6 6.8 12.1 9.9 6.4 12.1 1.2 1 0 0 1 1 1 0 SPATIAL MDM10 PF12519.8 GAN05664.1 - 4.5e-88 296.2 7.3 1.7e-50 172.3 1.3 3.2 1 1 2 3 3 3 3 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 GAN05664.1 - 4.7e-08 32.8 0.1 3.1e-06 26.9 0.0 2.3 2 1 1 3 3 3 2 Eukaryotic porin Cpn60_TCP1 PF00118.24 GAN05665.1 - 1.2e-153 512.3 19.1 1.4e-153 512.1 19.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 GAN05665.1 - 0.00033 20.2 0.3 0.0019 17.7 0.1 2.2 2 0 0 2 2 2 1 Telomere recombination SCAB_CC PF16712.5 GAN05665.1 - 0.01 15.7 1.6 0.016 15.1 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein DUF2536 PF10750.9 GAN05665.1 - 0.038 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) eRF1_2 PF03464.15 GAN05666.1 - 1.1e-44 152.0 0.1 1.9e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAN05666.1 - 1.4e-36 125.4 0.0 3.2e-36 124.3 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GAN05666.1 - 7.9e-19 67.9 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 GAN05666.1 - 2.1e-08 34.5 0.0 3.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 GAN05666.1 - 7e-08 32.8 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Pkinase PF00069.25 GAN05667.1 - 1.1e-76 257.7 0.0 1.4e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05667.1 - 1.4e-36 126.1 0.0 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05667.1 - 4.9e-07 29.3 0.0 7.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN05667.1 - 0.76 8.7 5.0 0.11 11.4 0.2 2.1 2 1 0 2 2 2 0 Haspin like kinase domain DUF1838 PF08894.11 GAN05668.1 - 1.1e-85 287.2 0.7 1.7e-85 286.5 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) CUE PF02845.16 GAN05668.1 - 8.8e-12 44.5 0.0 2.4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 CUE domain PhoLip_ATPase_C PF16212.5 GAN05669.1 - 1.3e-84 283.8 24.1 1.3e-84 283.8 24.1 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 GAN05669.1 - 6.1e-12 46.3 0.1 3.2e-07 30.9 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN05669.1 - 6.2e-12 45.4 0.0 5.4e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) PhoLip_ATPase_N PF16209.5 GAN05669.1 - 2.9e-09 36.5 2.6 1.3e-07 31.2 0.4 2.9 1 1 1 2 2 2 2 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GAN05669.1 - 1.2e-05 24.9 0.0 4.3e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAN05669.1 - 0.0012 18.6 0.5 0.0068 16.2 0.4 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PH_18 PF18469.1 GAN05669.1 - 0.0045 17.0 2.8 0.87 9.6 0.3 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain DHHC PF01529.20 GAN05670.1 - 1.6e-38 131.8 7.5 1.6e-38 131.8 7.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4064 PF13273.6 GAN05670.1 - 0.011 15.9 3.7 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) QueC PF06508.13 GAN05670.1 - 0.12 11.9 2.9 0.18 11.3 2.9 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Vpu PF00558.19 GAN05670.1 - 0.12 12.1 0.2 9.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Vpu protein Noc2 PF03715.13 GAN05671.1 - 1.5e-95 319.9 0.1 1.5e-95 319.9 0.1 1.6 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 GAN05671.1 - 3.4e-05 22.3 14.7 0.061 11.5 13.5 2.7 3 0 0 3 3 3 2 Nop14-like family Nic96 PF04097.14 GAN05672.1 - 1.6e-142 476.1 9.3 2.2e-142 475.7 9.3 1.1 1 0 0 1 1 1 1 Nup93/Nic96 IL5 PF02025.15 GAN05672.1 - 0.025 14.8 0.3 1.6 9.0 0.0 3.3 2 1 0 2 2 2 0 Interleukin 5 Ribosomal_S18 PF01084.20 GAN05673.1 - 2.4e-21 75.7 0.1 5.2e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 GDI PF00996.18 GAN05674.1 - 2.2e-216 718.5 0.4 2.5e-216 718.3 0.4 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor IMS PF00817.20 GAN05676.1 - 1e-38 132.7 0.1 2.9e-38 131.2 0.1 1.9 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 GAN05676.1 - 6.7e-17 61.7 0.1 1.7e-16 60.4 0.1 1.8 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 GAN05676.1 - 2.6e-13 50.7 0.0 6.8e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 GAN05676.1 - 4.5e-13 49.4 0.0 1.5e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAN05676.1 - 9.6e-07 29.1 0.0 4e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAN05676.1 - 1.3e-06 28.6 0.0 4.4e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 GAN05676.1 - 3e-05 24.1 0.0 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 GAN05676.1 - 6.8e-05 22.7 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Cdd1 PF11731.8 GAN05676.1 - 0.025 14.8 0.0 0.083 13.1 0.0 1.9 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.11 GAN05676.1 - 0.13 12.6 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) UBM PF14377.6 GAN05676.1 - 3.3 7.3 11.4 0.84 9.2 0.1 3.6 3 0 0 3 3 3 0 Ubiquitin binding region STIMATE PF12400.8 GAN05677.1 - 2.1e-40 138.2 11.7 3.7e-40 137.4 11.7 1.4 1 0 0 1 1 1 1 STIMATE family DUF4834 PF16118.5 GAN05677.1 - 0.15 13.1 0.0 0.15 13.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 GAN05677.1 - 0.27 11.1 0.1 0.27 11.1 0.1 1.6 2 0 0 2 2 2 0 TMEM9 Sigma_reg_N PF13800.6 GAN05677.1 - 9.2 6.6 7.1 4.7 7.6 0.3 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal MR_MLE_C PF13378.6 GAN05678.1 - 1.7e-55 187.9 0.1 2.7e-55 187.3 0.1 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAN05678.1 - 5.5e-05 23.4 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain EBP PF05241.12 GAN05679.1 - 0.17 11.3 3.4 0.32 10.4 3.4 1.7 1 1 0 1 1 1 0 Emopamil binding protein ABC_tran PF00005.27 GAN05680.1 - 1.5e-46 158.3 1.8 2.5e-28 99.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 GAN05680.1 - 2.5e-42 145.5 28.2 1.6e-26 93.6 15.0 4.0 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.19 GAN05680.1 - 7.1e-10 38.7 5.2 0.00037 20.0 3.3 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN05680.1 - 7.2e-06 26.3 0.4 0.12 12.6 0.1 3.0 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAN05680.1 - 3.1e-05 23.2 0.0 0.082 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 GAN05680.1 - 0.00038 20.6 1.2 0.037 14.1 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 GAN05680.1 - 0.001 18.8 2.3 0.14 11.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GAN05680.1 - 0.0016 19.0 5.5 0.27 11.7 0.1 3.2 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 GAN05680.1 - 0.0019 17.4 0.8 0.054 12.7 0.2 3.2 3 1 0 3 3 3 1 NB-ARC domain IstB_IS21 PF01695.17 GAN05680.1 - 0.0065 16.2 0.1 3 7.6 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF2075 PF09848.9 GAN05680.1 - 0.007 15.6 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Tubulin PF00091.25 GAN05680.1 - 0.011 16.0 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain AAA_25 PF13481.6 GAN05680.1 - 0.016 14.8 0.2 6.4 6.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 GAN05680.1 - 0.017 14.6 0.7 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 GAN05680.1 - 0.017 15.5 0.2 0.86 10.0 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 GAN05680.1 - 0.021 14.4 0.1 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAN05680.1 - 0.021 14.5 0.3 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAN05680.1 - 0.021 13.7 0.7 3.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 GAN05680.1 - 0.043 13.2 0.3 7.2 5.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 GAN05680.1 - 0.047 13.0 2.9 1.3 8.3 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_5 PF07728.14 GAN05680.1 - 0.056 13.4 0.1 35 4.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAN05680.1 - 0.066 13.6 0.3 11 6.5 0.0 3.0 3 0 0 3 3 2 0 RNA helicase RsgA_GTPase PF03193.16 GAN05680.1 - 0.074 12.9 0.1 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ResIII PF04851.15 GAN05680.1 - 0.11 12.5 0.2 6.4 6.8 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 GAN05680.1 - 0.15 12.0 0.6 22 4.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 GAN05680.1 - 0.15 12.2 0.3 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 GAN05680.1 - 2.2 8.0 4.8 13 5.4 0.5 3.1 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system CTP_transf_like PF01467.26 GAN05681.1 - 1.2e-46 158.5 0.1 1.9e-27 96.2 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 GAN05681.1 - 0.00017 21.5 1.8 0.6 10.0 0.2 3.1 3 1 0 3 3 3 2 FAD synthetase ScdA_N PF04405.14 GAN05681.1 - 0.0043 16.7 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown function (DUF542) Pantoate_ligase PF02569.15 GAN05681.1 - 0.027 13.7 0.1 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase CoA_binding_3 PF13727.6 GAN05681.1 - 0.13 12.3 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 CoA-binding domain GPI-anchored PF10342.9 GAN05683.1 - 1.2e-10 42.0 0.3 1.2e-10 42.0 0.3 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FtsK_alpha PF17854.1 GAN05683.1 - 0.5 10.5 0.0 0.5 10.5 0.0 3.1 3 2 0 3 3 3 0 FtsK alpha domain Thioredoxin PF00085.20 GAN05684.1 - 2.3e-66 220.2 2.9 1.5e-36 124.5 0.2 4.2 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 GAN05684.1 - 4.6e-46 157.0 3.7 1.8e-31 109.5 0.8 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAN05684.1 - 1.5e-09 38.2 2.7 0.00072 20.0 0.3 4.5 3 3 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAN05684.1 - 2.7e-08 33.9 0.4 0.0037 17.4 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.6 GAN05684.1 - 4.1e-08 33.5 0.1 0.0091 16.3 0.0 4.9 4 2 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 GAN05684.1 - 1e-07 31.6 0.1 0.0025 17.2 0.1 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family ERp29_N PF07912.13 GAN05684.1 - 9.3e-07 29.0 1.0 0.053 13.7 0.0 3.8 4 1 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 GAN05684.1 - 0.0001 22.3 0.0 0.045 13.8 0.1 3.0 2 0 0 2 2 2 1 Thioredoxin domain Calsequestrin PF01216.17 GAN05684.1 - 0.00017 20.8 7.2 0.0039 16.3 2.0 3.3 2 1 2 4 4 4 1 Calsequestrin AhpC-TSA PF00578.21 GAN05684.1 - 0.0011 18.8 0.4 1.4 8.8 0.1 3.0 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.6 GAN05684.1 - 0.0083 15.9 0.1 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 GAN05684.1 - 0.02 14.7 0.1 5.3 6.8 0.0 3.3 2 1 1 3 3 3 0 DSBA-like thioredoxin domain NIBRIN_BRCT_II PF16508.5 GAN05684.1 - 0.06 13.7 0.0 0.88 9.9 0.0 2.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein DUF836 PF05768.14 GAN05684.1 - 0.072 13.5 0.8 0.25 11.8 0.1 2.3 3 0 0 3 3 2 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.11 GAN05684.1 - 0.15 12.0 0.2 5 7.1 0.0 3.3 3 1 1 4 4 4 0 Hydrogenase-1 expression protein HyaE CorA PF01544.18 GAN05685.1 - 2.7e-45 154.9 3.1 4.1e-45 154.3 3.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BBP1_N PF15271.6 GAN05685.1 - 0.044 14.6 2.2 0.26 12.1 0.0 2.8 2 1 1 3 3 3 0 Spindle pole body component BBP1, Mps2-binding protein BTG PF07742.12 GAN05686.1 - 1e-34 118.8 0.0 1.4e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 BTG family ECH_1 PF00378.20 GAN05687.1 - 8.1e-51 172.8 0.0 9.9e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN05687.1 - 8.6e-30 104.4 0.4 2e-29 103.2 0.1 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase UPF0444 PF15475.6 GAN05687.1 - 0.01 16.1 1.0 0.02 15.2 1.0 1.4 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Homeodomain PF00046.29 GAN05688.1 - 3.6e-22 78.0 2.2 1.9e-21 75.7 1.2 2.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 GAN05688.1 - 0.054 13.4 0.2 0.054 13.4 0.2 3.1 3 0 0 3 3 3 0 Homeobox KN domain Arrestin_N PF00339.29 GAN05689.1 - 6.7e-10 39.2 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Peptidase_C12 PF01088.21 GAN05690.1 - 8.1e-47 159.7 0.0 1.6e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SPRY PF00622.28 GAN05690.1 - 2e-06 27.9 0.1 2.3e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 SPRY domain PHD PF00628.29 GAN05690.1 - 0.0038 17.1 1.4 0.0091 15.9 1.4 1.6 1 0 0 1 1 1 1 PHD-finger tRNA-synt_2 PF00152.20 GAN05691.1 - 5.7e-80 268.7 0.3 7.4e-80 268.4 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAN05691.1 - 3.9e-13 49.2 0.0 9.9e-13 47.9 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAN05691.1 - 3.8e-09 36.4 0.1 0.00061 19.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SWIRM PF04433.17 GAN05691.1 - 0.071 13.5 0.0 0.32 11.4 0.0 2.3 1 0 0 1 1 1 0 SWIRM domain Septin PF00735.18 GAN05692.1 - 8.6e-107 356.6 0.0 1.6e-106 355.7 0.0 1.4 1 0 0 1 1 1 1 Septin PPR_3 PF13812.6 GAN05692.1 - 2.1e-13 50.1 2.3 0.0016 18.5 0.1 4.7 3 2 2 5 5 5 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAN05692.1 - 5.2e-11 42.6 4.5 0.0028 17.8 0.0 5.8 4 2 2 6 6 6 3 PPR repeat family PPR PF01535.20 GAN05692.1 - 3.6e-07 30.0 2.1 0.0029 17.7 0.2 5.4 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 GAN05692.1 - 2.3e-06 27.2 2.7 0.69 9.2 0.0 3.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP MMR_HSR1 PF01926.23 GAN05692.1 - 3.7e-06 27.0 0.0 2.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Clathrin PF00637.20 GAN05692.1 - 0.0021 17.9 5.8 0.45 10.4 0.9 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS PPR_1 PF12854.7 GAN05692.1 - 0.02 14.6 0.0 16 5.3 0.0 3.8 4 0 0 4 4 4 0 PPR repeat GTP_EFTU PF00009.27 GAN05692.1 - 0.024 14.2 0.1 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain BTAD PF03704.17 GAN05692.1 - 0.052 14.0 9.7 0.16 12.4 0.6 3.3 3 1 1 4 4 4 0 Bacterial transcriptional activator domain tRNA_synthFbeta PF17759.1 GAN05692.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain TPR_14 PF13428.6 GAN05692.1 - 0.06 14.2 0.7 3.7 8.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MNE1 PF13762.6 GAN05692.1 - 0.062 13.3 0.1 0.53 10.3 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial splicing apparatus component TPR_12 PF13424.6 GAN05692.1 - 0.073 13.4 0.6 13 6.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RF-1 PF00472.20 GAN05692.1 - 0.096 12.6 1.5 0.2 11.6 0.8 2.0 2 0 0 2 2 2 0 RF-1 domain Ras PF00071.22 GAN05693.1 - 5e-59 198.5 0.2 6.5e-59 198.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN05693.1 - 8.4e-38 129.3 0.1 1.4e-37 128.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN05693.1 - 5.1e-16 58.6 0.1 6.5e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAN05693.1 - 1.1e-06 28.6 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAN05693.1 - 2.6e-06 27.1 0.0 3.8e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAN05693.1 - 8.6e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAN05693.1 - 1.4e-05 25.2 0.0 2.8e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN05693.1 - 2.2e-05 23.9 0.1 3.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 GAN05693.1 - 0.0022 17.8 0.0 0.0083 15.9 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TIR_2 PF13676.6 GAN05693.1 - 0.039 14.6 0.1 0.085 13.5 0.1 1.5 1 1 0 1 1 1 0 TIR domain AAA_7 PF12775.7 GAN05693.1 - 0.049 13.1 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TetR_C_16 PF17920.1 GAN05693.1 - 0.081 13.2 0.0 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Acetyltransf_1 PF00583.25 GAN05694.1 - 2.1e-18 66.7 0.0 2.4e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN05694.1 - 6.7e-15 55.1 0.1 8.5e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN05694.1 - 6.9e-13 48.8 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN05694.1 - 2e-08 34.1 0.2 5.9e-08 32.6 0.0 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 GAN05694.1 - 4.3e-06 26.8 0.0 8.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAN05694.1 - 7.5e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAN05694.1 - 0.0014 19.3 0.0 0.0016 19.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAN05694.1 - 0.0015 18.0 0.0 0.0038 16.7 0.0 1.8 1 1 0 1 1 1 1 Putative acetyl-transferase PanZ PF12568.8 GAN05694.1 - 0.0029 17.3 0.1 0.0032 17.2 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ GNAT_acetyltran PF12746.7 GAN05694.1 - 0.023 14.3 0.1 0.037 13.6 0.1 1.6 1 1 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_13 PF13880.6 GAN05694.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF2156 PF09924.9 GAN05694.1 - 0.035 13.1 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Acetyltransf_4 PF13420.7 GAN05694.1 - 0.041 14.0 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Carn_acyltransf PF00755.20 GAN05695.1 - 2.2e-216 720.0 0.2 2.6e-216 719.8 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_16 PF13191.6 GAN05696.1 - 8.9e-09 36.0 0.0 1.7e-07 31.8 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 GAN05696.1 - 0.003 17.9 0.0 0.0087 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 GAN05696.1 - 0.0075 16.8 0.0 0.052 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 GAN05696.1 - 0.021 14.7 0.0 0.067 13.1 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 GAN05696.1 - 0.024 14.4 0.0 0.073 12.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 GAN05696.1 - 0.043 14.1 0.2 0.54 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 GAN05696.1 - 0.075 12.9 0.1 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Phage_F PF02305.17 GAN05697.1 - 0.082 11.6 0.0 0.088 11.5 0.0 1.0 1 0 0 1 1 1 0 Capsid protein (F protein) Arrestin_C PF02752.22 GAN05698.1 - 3.3e-17 63.2 0.1 9.2e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN05698.1 - 1.9e-16 60.5 0.0 3.7e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN05698.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like CTK3 PF12243.8 GAN05699.1 - 3.8e-29 101.2 0.1 7.2e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 GAN05699.1 - 4.2e-16 58.9 8.5 4.2e-16 58.9 8.5 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus CTD_bind PF04818.13 GAN05699.1 - 0.0066 17.3 0.0 0.021 15.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. NDUFB11 PF17250.2 GAN05699.1 - 0.049 14.3 0.5 0.1 13.3 0.5 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit P66_CC PF16563.5 GAN05699.1 - 0.41 10.3 0.0 0.41 10.3 0.0 2.5 2 1 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 LRR_9 PF14580.6 GAN05700.1 - 3.5e-18 65.7 19.7 7.7e-10 38.5 3.4 3.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 GAN05700.1 - 5.2e-16 58.5 34.3 0.00071 19.9 1.4 5.8 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAN05700.1 - 6.4e-12 45.0 33.2 0.00027 20.6 7.1 5.5 2 2 3 5 5 5 5 Leucine rich repeat Rogdi_lz PF10259.9 GAN05701.1 - 4.4e-21 75.5 0.1 4.3e-20 72.3 0.1 1.9 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein bZIP_1 PF00170.21 GAN05702.1 - 1.4e-11 44.3 10.8 3.3e-11 43.1 10.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN05702.1 - 2e-08 34.2 8.1 2e-08 34.2 8.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper Macoilin PF09726.9 GAN05702.1 - 0.0011 17.7 9.8 0.0016 17.1 9.8 1.3 1 0 0 1 1 1 1 Macoilin family Jnk-SapK_ap_N PF09744.9 GAN05702.1 - 0.061 13.5 6.5 0.13 12.5 6.5 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 GAN05702.1 - 0.23 12.1 2.2 0.64 10.7 2.2 1.7 1 0 0 1 1 1 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 GAN05702.1 - 1.4 9.1 4.5 1 9.5 1.1 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain bZIP_Maf PF03131.17 GAN05702.1 - 6.1 7.4 14.3 1 9.9 7.4 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF812 PF05667.11 GAN05702.1 - 7.8 5.3 15.6 26 3.5 15.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) WTF PF03303.13 GAN05703.1 - 0.39 10.4 1.5 0.52 10.0 0.3 1.8 1 1 1 2 2 2 0 WTF protein Sterol-sensing PF12349.8 GAN05704.1 - 1.5e-29 102.8 4.5 4.7e-29 101.2 4.5 1.9 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAN05704.1 - 8.6e-14 50.6 5.7 1.3e-13 49.9 5.7 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 GAN05704.1 - 1.7e-11 44.4 19.7 0.03 15.2 2.2 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 GAN05704.1 - 1.1e-05 24.3 10.5 0.063 11.9 0.2 5.1 4 1 2 6 6 6 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN05704.1 - 0.00038 20.7 3.5 2.9 8.2 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pex24p PF06398.11 GAN05704.1 - 0.0069 15.4 0.9 0.35 9.8 0.9 2.4 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Hira PF07569.11 GAN05704.1 - 0.037 13.8 3.4 3.5 7.3 0.2 4.1 4 0 0 4 4 4 0 TUP1-like enhancer of split GPI-anchored PF10342.9 GAN05705.1 - 1.4e-07 32.2 0.4 2.1e-07 31.6 0.4 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_6 PF17936.1 GAN05705.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig domain MFS_1 PF07690.16 GAN05706.1 - 2.9e-36 125.2 46.1 1.9e-31 109.3 21.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily YCII PF03795.14 GAN05706.1 - 1.1e-07 32.2 0.0 2.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 YCII-related domain OATP PF03137.20 GAN05706.1 - 1.1e-05 24.0 2.6 0.00029 19.3 1.0 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Trp_oprn_chp PF09534.10 GAN05706.1 - 5.9e-05 22.9 0.8 0.012 15.4 0.0 2.3 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HATPase_c PF02518.26 GAN05708.1 - 1.3e-31 109.4 0.1 3e-31 108.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAN05708.1 - 5.5e-21 74.8 0.1 8.7e-20 71.0 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 GAN05708.1 - 3.1e-17 63.5 0.1 1.7e-16 61.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 GAN05708.1 - 7.6e-16 57.9 0.0 2.6e-15 56.2 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 GAN05708.1 - 6.8e-10 39.4 0.0 2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 GAN05708.1 - 1.5e-09 37.6 0.0 3.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 GAN05708.1 - 2.7e-07 31.3 0.0 6.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 GAN05708.1 - 4.1e-05 22.9 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Pkinase_Tyr PF07714.17 GAN05708.1 - 0.00081 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ABC_tran PF00005.27 GAN05708.1 - 0.025 15.1 0.0 0.07 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAN05708.1 - 0.041 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN05708.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAN05708.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase PH PF00169.29 GAN05709.1 - 0.00091 19.7 0.0 0.003 18.0 0.0 1.9 1 0 0 1 1 1 1 PH domain MIOX PF05153.15 GAN05710.1 - 3e-108 361.1 6.5 4e-108 360.7 6.5 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 GAN05710.1 - 0.0064 16.7 1.2 1.1 9.5 0.0 2.5 1 1 1 2 2 2 2 HD domain LcrG PF07216.12 GAN05710.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 LcrG protein CDC50 PF03381.15 GAN05711.1 - 5.4e-88 295.1 0.3 7.8e-88 294.6 0.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATG27 PF09451.10 GAN05711.1 - 1.5e-40 139.8 0.0 2.2e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAN05711.1 - 0.014 14.5 0.1 0.036 13.2 0.0 1.6 2 0 0 2 2 2 0 Mannose-6-phosphate receptor DUF4366 PF14283.6 GAN05711.1 - 0.086 12.9 0.0 0.086 12.9 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Not1 PF04054.15 GAN05712.1 - 4.5e-118 394.3 0.7 1.4e-117 392.7 0.4 2.1 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAN05712.1 - 1.7e-89 299.0 3.7 3.6e-89 298.0 2.6 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 GAN05712.1 - 1.7e-55 187.2 0.0 1.7e-55 187.2 0.0 2.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 GAN05712.1 - 1.7e-42 144.8 0.6 1.7e-42 144.8 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 GAN05712.1 - 3.8e-36 124.4 0.3 3.8e-36 124.4 0.3 2.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat SwrA PF17423.2 GAN05712.1 - 0.049 13.6 0.0 0.39 10.7 0.0 2.6 1 0 0 1 1 1 0 Swarming motility protein Metallophos PF00149.28 GAN05713.1 - 4.7e-13 50.1 1.1 5.7e-13 49.8 1.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 GAN05713.1 - 6.3e-05 21.5 0.1 0.00018 19.9 0.0 1.7 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Usp PF00582.26 GAN05714.1 - 2.8e-25 89.5 0.5 3.9e-25 89.0 0.1 1.4 2 0 0 2 2 2 1 Universal stress protein family ADH_zinc_N PF00107.26 GAN05714.1 - 0.0055 16.7 0.1 0.079 12.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF4854 PF16146.5 GAN05714.1 - 0.46 10.8 3.3 0.36 11.2 0.8 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4854) GDI PF00996.18 GAN05715.1 - 4.3e-218 724.1 0.0 5e-218 723.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 GAN05715.1 - 0.0016 17.8 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase RE_Bsp6I PF09504.10 GAN05715.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Bsp6I restriction endonuclease DUF2802 PF10975.8 GAN05716.1 - 0.091 12.9 3.2 0.41 10.8 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) DUF1068 PF06364.12 GAN05716.1 - 0.54 10.1 7.0 1.8 8.4 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1068) FAM76 PF16046.5 GAN05716.1 - 1.9 7.8 7.4 2.2 7.5 7.4 1.1 1 0 0 1 1 1 0 FAM76 protein Longin PF13774.6 GAN05717.1 - 2.4e-29 101.2 0.1 3.8e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAN05717.1 - 3.2e-14 52.5 0.0 5.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Imm70 PF15601.6 GAN05717.1 - 0.076 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 70 SLM4 PF16818.5 GAN05717.1 - 0.098 12.6 0.1 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein SLM4 MCD PF05292.11 GAN05718.1 - 3.3e-84 282.5 0.0 7.7e-84 281.3 0.0 1.6 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 GAN05718.1 - 1.4e-10 41.1 0.1 3.7e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain RabGAP-TBC PF00566.18 GAN05719.1 - 3.4e-46 157.6 0.2 7.6e-46 156.5 0.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MBF1 PF08523.10 GAN05719.1 - 2.6e-19 69.4 4.1 8.5e-19 67.8 4.1 2.0 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 GAN05719.1 - 5.3e-12 45.6 0.3 1.1e-11 44.6 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 GAN05719.1 - 0.0092 16.0 0.4 0.022 14.7 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain PMR5N PF14416.6 GAN05720.1 - 0.0019 18.5 0.2 0.0025 18.1 0.2 1.2 1 0 0 1 1 1 1 PMR5 N terminal Domain PLA2_B PF01735.18 GAN05721.1 - 7.2e-39 133.5 2.3 1.5e-18 66.5 0.9 3.0 3 0 0 3 3 3 2 Lysophospholipase catalytic domain DUF1454 PF07305.12 GAN05721.1 - 0.015 14.8 0.2 0.072 12.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1454) NDUF_B6 PF09782.9 GAN05721.1 - 0.15 12.2 0.7 5.7 7.1 0.0 2.8 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Mst1_SARAH PF11629.8 GAN05721.1 - 0.17 12.0 3.1 0.31 11.1 0.1 2.9 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 DUF3391 PF11871.8 GAN05721.1 - 0.58 10.7 7.3 0.33 11.5 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) CPSF100_C PF13299.6 GAN05721.1 - 5.2 7.2 9.3 35 4.5 5.3 2.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Lipase_GDSL PF00657.22 GAN05722.1 - 1.1e-09 38.5 0.2 1.6e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN05722.1 - 5.5e-07 30.1 0.1 7.6e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_S48 PF03574.15 GAN05722.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S48 Glyco_transf_20 PF00982.21 GAN05723.1 - 5.8e-153 510.0 0.0 7.9e-153 509.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN05723.1 - 1.3e-76 256.8 0.0 2.4e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 GAN05723.1 - 1e-06 28.7 0.0 0.00041 20.2 0.0 3.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.11 GAN05723.1 - 0.03 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Peptidase_M16_C PF05193.21 GAN05724.1 - 5.3e-15 55.9 0.0 1.1e-10 41.8 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAN05724.1 - 1.2e-06 28.6 0.0 8.4e-06 25.8 0.0 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF4611 PF15387.6 GAN05725.1 - 0.05 13.8 3.0 0.087 13.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) zf-RING_2 PF13639.6 GAN05726.1 - 1.3e-13 51.1 5.3 1.9e-13 50.5 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN05726.1 - 2.8e-10 39.7 2.6 2.8e-10 39.7 2.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAN05726.1 - 1.9e-08 34.0 4.7 3e-08 33.4 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN05726.1 - 2.3e-08 33.8 5.2 3.6e-08 33.1 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN05726.1 - 6.9e-07 29.5 7.8 2.4e-06 27.7 7.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAN05726.1 - 1e-06 28.5 2.6 1.5e-06 27.9 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN05726.1 - 4.2e-06 26.6 3.8 6.2e-06 26.1 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN05726.1 - 2.4e-05 24.1 3.6 4.6e-05 23.2 3.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAN05726.1 - 2.6e-05 24.2 3.3 0.00077 19.4 0.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAN05726.1 - 0.00039 20.4 4.0 0.0012 18.9 4.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAN05726.1 - 0.0026 17.5 4.0 0.0055 16.5 3.8 1.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain DUF2681 PF10883.8 GAN05726.1 - 0.0038 17.6 0.3 0.011 16.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) DUF4079 PF13301.6 GAN05726.1 - 0.016 15.4 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Zn_ribbon_17 PF17120.5 GAN05726.1 - 0.016 14.8 4.0 0.026 14.1 4.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 GAN05726.1 - 0.036 14.2 5.6 0.29 11.3 5.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 GAN05726.1 - 0.037 14.2 1.7 0.075 13.2 1.7 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 GAN05726.1 - 0.1 12.9 3.1 0.2 12.0 3.1 1.5 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 GAN05726.1 - 0.14 12.1 4.4 0.24 11.3 4.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 GAN05726.1 - 0.29 11.2 4.9 1.1 9.3 4.9 2.0 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 GAN05726.1 - 0.38 10.9 6.1 0.94 9.7 5.5 1.9 1 1 1 2 2 2 0 RING-variant domain Vps39_2 PF10367.9 GAN05726.1 - 4.1 7.9 6.4 4.1 7.9 1.5 2.5 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Pkinase PF00069.25 GAN05727.1 - 5.1e-55 186.7 0.0 4.2e-48 164.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05727.1 - 1.4e-28 99.9 0.0 3.7e-19 69.0 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 GAN05727.1 - 1.2e-06 28.0 0.0 1.4e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN05727.1 - 0.016 14.0 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GAN05727.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ZirS_C PF16583.5 GAN05727.1 - 0.17 11.5 0.1 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Glyco_transf_22 PF03901.17 GAN05728.1 - 9.7e-82 275.4 19.7 1.2e-81 275.1 19.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Spc42p PF11544.8 GAN05730.1 - 0.0053 16.7 2.3 0.0053 16.7 2.3 2.1 2 0 0 2 2 2 1 Spindle pole body component Spc42p CCDC-167 PF15188.6 GAN05730.1 - 0.0068 16.7 2.9 0.0068 16.7 2.9 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 167 GAS PF13851.6 GAN05730.1 - 0.0074 15.7 15.2 0.053 12.9 6.4 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 GAN05730.1 - 0.022 15.2 11.0 0.49 10.9 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 CEP209_CC5 PF16574.5 GAN05730.1 - 0.023 14.9 2.0 0.023 14.9 2.0 2.4 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 SlyX PF04102.12 GAN05730.1 - 0.031 14.9 7.7 0.078 13.6 2.0 2.8 1 1 1 2 2 2 0 SlyX PDCD7 PF16021.5 GAN05730.1 - 0.036 13.2 6.1 0.047 12.8 6.1 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 Tropomyosin_1 PF12718.7 GAN05730.1 - 0.037 14.2 15.3 0.081 13.1 4.6 2.1 1 1 1 2 2 2 0 Tropomyosin like ADIP PF11559.8 GAN05730.1 - 0.048 13.7 14.8 0.29 11.2 3.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HEPN_Toprim_N PF18871.1 GAN05730.1 - 0.049 13.6 4.4 0.17 11.8 4.4 1.7 1 1 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Interferon PF00143.19 GAN05730.1 - 0.06 13.5 6.5 0.28 11.3 1.0 2.2 1 1 1 2 2 2 0 Interferon alpha/beta domain TACC_C PF05010.14 GAN05730.1 - 0.092 12.5 11.2 0.36 10.6 11.2 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MCPsignal PF00015.21 GAN05730.1 - 0.1 12.4 3.9 1 9.1 0.3 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Phage_GP20 PF06810.11 GAN05730.1 - 0.1 12.4 11.9 0.19 11.5 1.2 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Laminin_II PF06009.12 GAN05730.1 - 0.11 12.5 6.2 0.11 12.5 1.2 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 GAN05730.1 - 0.13 12.3 5.2 3.8 7.6 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 GAN05730.1 - 0.15 12.8 8.0 0.65 10.7 0.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CortBP2 PF09727.9 GAN05730.1 - 0.15 11.9 11.7 0.64 9.9 11.6 1.8 1 1 0 1 1 1 0 Cortactin-binding protein-2 Spc7 PF08317.11 GAN05730.1 - 0.15 10.9 14.0 0.36 9.7 14.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein FH2 PF02181.23 GAN05730.1 - 0.17 11.0 10.3 1.3 8.0 10.0 1.9 1 1 0 1 1 1 0 Formin Homology 2 Domain DUF3138 PF11336.8 GAN05730.1 - 0.19 10.3 0.5 0.27 9.8 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.12 GAN05730.1 - 0.2 12.2 4.2 1.7 9.1 4.2 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 GAN05730.1 - 0.2 11.3 11.8 5.2 6.7 11.8 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Exonuc_VII_L PF02601.15 GAN05730.1 - 0.22 11.0 6.8 0.29 10.6 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 GAN05730.1 - 0.23 11.2 12.5 1.1 9.1 1.1 2.9 2 1 1 3 3 3 0 Septum formation initiator SpecificRecomb PF10136.9 GAN05730.1 - 0.27 9.5 4.8 0.35 9.1 4.8 1.1 1 0 0 1 1 1 0 Site-specific recombinase Filament PF00038.21 GAN05730.1 - 0.32 10.5 12.5 0.34 10.4 4.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 GAN05730.1 - 0.33 11.1 9.8 0.53 10.5 2.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 GAN05730.1 - 0.34 9.5 11.5 0.75 8.4 11.5 1.5 1 1 0 1 1 1 0 AAA domain HemX PF04375.14 GAN05730.1 - 0.34 10.1 9.1 12 5.0 9.1 2.0 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Herpes_UL6 PF01763.16 GAN05730.1 - 0.43 9.0 5.3 0.45 9.0 4.9 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like HrpB7 PF09486.10 GAN05730.1 - 0.47 10.8 8.7 4.6 7.6 6.6 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) FliJ PF02050.16 GAN05730.1 - 0.54 10.5 11.0 3.1 8.1 6.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein PRKG1_interact PF15898.5 GAN05730.1 - 0.54 11.2 10.1 5.3 8.0 10.1 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4795 PF16043.5 GAN05730.1 - 0.56 9.8 10.1 2.9 7.5 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4446 PF14584.6 GAN05730.1 - 0.59 10.1 8.7 3.4 7.7 1.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) FapA PF03961.13 GAN05730.1 - 0.64 8.6 7.4 1.1 7.7 7.4 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 GAN05730.1 - 0.65 10.7 8.9 7.2 7.4 0.4 2.2 1 1 1 2 2 2 0 Occludin homology domain Uso1_p115_C PF04871.13 GAN05730.1 - 0.69 10.3 13.6 0.2 12.0 3.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lectin_N PF03954.14 GAN05730.1 - 0.69 9.6 6.5 1 9.1 1.8 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain USP8_interact PF08941.10 GAN05730.1 - 0.71 9.7 5.6 0.44 10.4 1.3 1.9 1 1 1 2 2 2 0 USP8 interacting Uds1 PF15456.6 GAN05730.1 - 0.73 10.0 8.0 1.9 8.7 8.0 1.6 1 1 0 1 1 1 0 Up-regulated During Septation TMPIT PF07851.13 GAN05730.1 - 0.75 9.0 10.6 0.24 10.6 4.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein Ly49 PF08391.10 GAN05730.1 - 0.97 9.8 7.7 0.22 11.9 1.7 2.1 1 1 0 2 2 2 0 Ly49-like protein, N-terminal region ATG16 PF08614.11 GAN05730.1 - 1 9.6 12.0 7.2 6.8 4.4 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 GAN05730.1 - 1.3 8.8 12.6 1.6 8.5 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 GAN05730.1 - 1.4 9.3 6.0 11 6.6 1.6 3.3 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 GAN05730.1 - 1.6 8.8 11.8 0.87 9.7 3.3 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 GAN05730.1 - 1.8 8.6 13.6 2.3 8.3 0.4 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MCU PF04678.13 GAN05730.1 - 2 8.5 9.1 1.3 9.1 1.1 2.0 1 1 1 2 2 2 0 Mitochondrial calcium uniporter APG6_N PF17675.1 GAN05730.1 - 2.2 8.8 17.3 1.9 9.0 7.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF641 PF04859.12 GAN05730.1 - 2.4 8.5 10.5 36 4.7 7.9 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.22 GAN05730.1 - 2.7 8.2 9.9 9.6 6.5 1.7 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 GAN05730.1 - 4.7 6.4 10.5 0.61 9.3 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 GAN05730.1 - 5.5 7.7 11.8 3 8.5 2.1 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 GAN05730.1 - 6.4 6.8 14.8 11 6.2 2.4 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Ras PF00071.22 GAN05731.1 - 1.5e-55 187.3 0.0 1.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN05731.1 - 2.3e-22 79.5 0.0 3.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN05731.1 - 3.8e-08 33.0 0.0 4.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PMT PF02366.18 GAN05732.1 - 1.4e-77 260.6 14.5 1.4e-77 260.6 14.5 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAN05732.1 - 2.1e-55 187.4 13.3 2.1e-55 187.4 13.3 2.1 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAN05732.1 - 4.9e-24 85.2 0.1 1e-23 84.2 0.1 1.5 1 0 0 1 1 1 1 MIR domain Aminotran_3 PF00202.21 GAN05733.1 - 2.7e-115 385.3 0.0 3.3e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAN05733.1 - 3.2e-05 23.3 0.0 7.8e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DNA_ligase_IV PF11411.8 GAN05733.1 - 0.017 15.2 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase IV CAP_GLY PF01302.25 GAN05735.1 - 2.1e-21 75.7 0.3 4.3e-21 74.7 0.3 1.6 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.31 GAN05735.1 - 9.3e-15 54.8 1.5 4.5e-11 43.0 0.1 2.8 2 1 0 2 2 2 2 BTB/POZ domain Lipase_3 PF01764.25 GAN05736.1 - 1e-38 132.4 0.0 1.6e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAN05736.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN05736.1 - 0.00021 22.0 0.0 0.00036 21.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 GAN05736.1 - 0.0015 18.2 0.4 0.012 15.2 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.20 GAN05736.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Sdh_cyt PF01127.22 GAN05738.1 - 1.9e-27 95.7 0.6 2.7e-27 95.2 0.6 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit UCH_1 PF13423.6 GAN05739.1 - 3.5e-97 325.8 0.5 4.7e-97 325.4 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 GAN05739.1 - 8.5e-22 78.4 0.0 3.4e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 GAN05739.1 - 4.8e-10 39.4 0.0 8.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Acyltransferase PF01553.21 GAN05740.1 - 1.1e-08 34.8 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CDC73_C PF05179.14 GAN05741.1 - 1.1e-41 142.2 0.3 2.1e-41 141.2 0.3 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Y_phosphatase2 PF03162.13 GAN05741.1 - 1.6e-41 141.7 0.0 3.5e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family CDC73_N PF16050.5 GAN05741.1 - 1.6e-20 73.6 1.8 1.9e-15 57.0 0.1 2.9 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal CNH PF00780.22 GAN05742.1 - 1.8e-59 201.6 0.0 3.2e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAN05742.1 - 3.1e-34 118.8 1.0 7.8e-34 117.5 1.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 GAN05742.1 - 5e-22 78.4 0.0 1.4e-21 77.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 GAN05742.1 - 0.2 11.5 3.6 0.33 10.8 1.2 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain UAE_UbL PF14732.6 GAN05744.1 - 0.1 13.2 0.7 0.32 11.6 0.7 1.8 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DUF1664 PF07889.12 GAN05744.1 - 0.14 12.2 5.1 0.33 11.0 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RAMPs PF03787.15 GAN05744.1 - 0.17 11.9 1.6 0.22 11.6 1.6 1.4 1 1 0 1 1 1 0 RAMP superfamily Prefoldin PF02996.17 GAN05744.1 - 0.33 10.9 7.4 0.074 13.0 3.3 2.0 2 0 0 2 2 2 0 Prefoldin subunit COG2 PF06148.11 GAN05744.1 - 0.78 9.8 5.8 0.56 10.3 0.4 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 GAN05744.1 - 2 8.4 10.7 3.4 7.7 10.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 GAN05745.1 - 2.1e-09 37.8 9.8 0.00045 21.0 0.2 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Pribosyltran PF00156.27 GAN05746.1 - 9.9e-19 67.4 0.1 1.2e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAN05746.1 - 0.00091 18.7 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 GAN05746.1 - 0.026 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Propeptide_C1 PF08127.13 GAN05746.1 - 0.079 12.9 0.2 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C1 propeptide TAP42 PF04177.12 GAN05747.1 - 1.2e-95 320.4 8.8 1.3e-95 320.2 8.8 1.0 1 0 0 1 1 1 1 TAP42-like family Trans_reg_C PF00486.28 GAN05747.1 - 0.047 13.8 0.1 0.3 11.2 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal FemAB PF02388.16 GAN05747.1 - 0.094 11.6 1.0 0.14 11.0 1.0 1.2 1 0 0 1 1 1 0 FemAB family NFACT-C PF11923.8 GAN05747.1 - 1.9 8.4 4.2 0.88 9.5 0.4 2.3 2 1 1 3 3 3 0 NFACT protein C-terminal domain Adaptin_N PF01602.20 GAN05748.1 - 7.7e-139 463.6 10.2 7.7e-139 463.6 10.2 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 GAN05748.1 - 2.8e-62 209.5 13.1 4.9e-62 208.7 0.3 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAN05748.1 - 1.1e-17 64.2 5.3 7.9e-08 32.6 0.3 4.9 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 GAN05748.1 - 4e-11 42.2 2.7 0.0073 16.5 0.0 6.3 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.23 GAN05748.1 - 2.8e-07 30.3 1.2 0.024 14.7 0.0 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAN05748.1 - 5.3e-05 23.6 4.1 1 9.9 0.0 6.0 6 1 1 7 7 7 2 HEAT-like repeat DUF4518 PF15008.6 GAN05748.1 - 0.5 9.5 13.9 0.99 8.5 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) TFIIA PF03153.13 GAN05748.1 - 2.6 8.0 29.8 4.8 7.1 29.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 GAN05748.1 - 2.9 8.5 16.9 6.3 7.4 16.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 GAN05748.1 - 4 7.4 15.1 9 6.3 15.1 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TatD_DNase PF01026.21 GAN05749.1 - 2.6e-35 122.0 0.0 3.1e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RRM_1 PF00076.22 GAN05750.1 - 5.8e-17 61.3 0.0 8.6e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAN05750.1 - 0.017 14.7 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 GAN05751.1 - 2.3e-18 65.9 0.1 5.9e-05 22.9 0.0 5.2 5 0 0 5 5 5 5 Mitochondrial carrier protein Abhydrolase_2 PF02230.16 GAN05752.1 - 8.1e-19 68.3 0.0 1.1e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAN05752.1 - 0.0024 18.5 0.0 0.0029 18.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN05752.1 - 0.014 14.7 0.0 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN05752.1 - 0.11 12.1 0.0 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF5476 PF17570.2 GAN05752.1 - 0.31 11.5 0.0 0.31 11.5 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5476) Prenylcys_lyase PF07156.14 GAN05753.1 - 3.7e-70 236.9 0.1 4.6e-70 236.6 0.1 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 GAN05753.1 - 5.2e-12 45.8 0.0 1e-11 44.9 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAN05753.1 - 4.7e-08 33.1 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAN05753.1 - 5.8e-06 26.1 0.4 0.0001 22.0 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN05753.1 - 0.0056 15.9 0.2 0.047 12.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN05753.1 - 0.0083 16.1 0.6 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding AA_permease_2 PF13520.6 GAN05754.1 - 7e-51 173.4 59.9 1.6e-41 142.5 46.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 GAN05754.1 - 1.3e-13 50.4 38.9 1.3e-13 50.4 38.9 2.0 1 1 1 2 2 2 1 Amino acid permease FGGY_N PF00370.21 GAN05755.1 - 2.4e-23 83.0 0.0 4.2e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAN05755.1 - 1.6e-19 70.4 0.0 3.7e-19 69.2 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MBOAT_2 PF13813.6 GAN05756.1 - 7e-19 67.9 0.5 1.7e-18 66.7 0.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Insulin_TMD PF17870.1 GAN05756.1 - 0.18 11.9 2.1 0.93 9.6 0.0 2.9 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment WD40 PF00400.32 GAN05757.1 - 1.5e-09 38.3 6.7 0.00024 21.8 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05757.1 - 3.8e-08 33.5 0.4 0.0054 17.0 0.0 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN05757.1 - 2.4e-07 30.4 0.1 0.00049 19.5 0.0 2.7 1 1 2 3 3 3 3 WD40-like domain RAB3GAP2_N PF14655.6 GAN05757.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus CAF1C_H4-bd PF12265.8 GAN05758.1 - 1.3e-27 95.9 0.7 5.6e-27 93.8 0.8 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAN05758.1 - 6.1e-25 87.0 13.6 6.4e-06 26.8 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05758.1 - 6e-06 26.5 0.1 0.75 10.1 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AIF-MLS PF14962.6 GAN05758.1 - 1 9.3 13.5 2.4 8.1 13.5 1.6 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF3336 PF11815.8 GAN05760.1 - 7.4e-36 122.9 1.3 3.8e-35 120.6 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAN05760.1 - 6.4e-20 72.2 0.0 1.1e-19 71.5 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Glyco_transf_49 PF13896.6 GAN05761.1 - 1.6e-56 192.1 8.9 3e-45 155.0 3.0 2.4 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan SAM_decarbox PF01536.16 GAN05762.1 - 2.6e-126 421.4 0.0 5.9e-126 420.2 0.0 1.5 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF5519 PF17648.1 GAN05762.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5519) WD40 PF00400.32 GAN05763.1 - 2.5e-21 75.6 6.4 2.6e-05 24.9 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05763.1 - 5.7e-10 39.4 0.1 0.0067 16.7 0.1 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN05763.1 - 7.1e-07 28.2 0.4 0.00072 18.3 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN05763.1 - 0.00019 20.5 1.3 2.7 6.8 0.0 3.7 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 GAN05763.1 - 0.016 14.9 1.5 2 8.1 0.0 3.6 4 0 0 4 4 4 0 TUP1-like enhancer of split PALB2_WD40 PF16756.5 GAN05763.1 - 0.02 13.8 1.3 3.2 6.6 0.2 3.0 2 2 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ank_4 PF13637.6 GAN05765.1 - 5.2e-19 68.4 2.5 2.6e-10 40.6 0.1 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN05765.1 - 5.5e-16 58.9 0.3 3.5e-09 37.1 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN05765.1 - 6.7e-13 47.6 3.2 2.8e-05 24.2 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAN05765.1 - 1.7e-11 44.2 0.0 2.6e-06 27.6 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAN05765.1 - 3e-11 43.2 3.7 2.1e-06 27.9 0.0 4.8 6 0 0 6 6 6 2 Ankyrin repeat Chordopox_A13L PF05961.11 GAN05765.1 - 0.07 13.4 1.2 2.7 8.3 0.3 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein MFS_Mycoplasma PF07672.13 GAN05765.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter SUIM_assoc PF16619.5 GAN05765.1 - 1.4 9.1 13.9 0.14 12.2 8.5 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 GAN05765.1 - 2.7 9.0 5.8 33 5.5 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) YajC PF02699.15 GAN05765.1 - 3.3 7.6 5.8 0.59 10.1 1.1 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit RRM_1 PF00076.22 GAN05766.1 - 1.1e-20 73.2 0.2 3.2e-15 55.7 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAS20 PF02064.15 GAN05766.1 - 0.05 13.7 4.9 0.13 12.4 4.9 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor RRM_7 PF16367.5 GAN05766.1 - 0.057 13.5 0.1 4 7.6 0.1 2.6 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 GAN05766.1 - 0.11 12.7 6.6 10 6.3 2.0 4.0 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Androgen_recep PF02166.16 GAN05766.1 - 0.12 11.2 23.8 0.25 10.2 0.2 2.4 2 0 0 2 2 2 0 Androgen receptor Plasmodium_Vir PF05795.11 GAN05766.1 - 0.24 10.8 6.6 0.46 9.8 6.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1681 PF07933.14 GAN05766.1 - 0.27 10.9 3.2 0.54 10.0 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) CCDC53 PF10152.9 GAN05766.1 - 0.29 11.5 7.9 1.6 9.1 3.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Hydin_ADK PF17213.3 GAN05766.1 - 1.2 9.4 16.2 0.92 9.8 2.4 2.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Activator_LAG-3 PF11498.8 GAN05766.1 - 2.3 7.1 31.2 0.77 8.7 18.7 2.9 3 0 0 3 3 3 0 Transcriptional activator LAG-3 Sugar_tr PF00083.24 GAN05767.1 - 1.9e-103 346.8 25.9 3.1e-53 181.3 14.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN05767.1 - 2.5e-30 105.6 13.0 2.5e-30 105.6 13.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN05768.1 - 3.7e-16 58.7 7.8 3.7e-16 58.7 7.8 2.8 4 0 0 4 4 4 1 MFS/sugar transport protein PUCC PF03209.15 GAN05768.1 - 0.00039 19.5 0.5 0.00067 18.8 0.5 1.3 1 0 0 1 1 1 1 PUCC protein SOR_SNZ PF01680.17 GAN05769.1 - 9.8e-113 375.0 6.0 9.8e-113 375.0 6.0 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 GAN05769.1 - 5.2e-10 39.1 8.6 6.6e-08 32.2 0.7 2.5 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 GAN05769.1 - 4.6e-05 22.7 0.2 0.25 10.4 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 GAN05769.1 - 0.00046 19.4 0.3 0.097 11.8 0.0 2.5 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 GAN05769.1 - 0.0027 17.8 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 GAN05769.1 - 0.012 15.1 0.4 0.17 11.3 0.0 2.4 2 1 0 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 GAN05769.1 - 0.041 13.0 0.2 0.75 8.9 0.0 2.7 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 GAN05769.1 - 0.052 12.9 4.5 0.32 10.3 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase OMPdecase PF00215.24 GAN05769.1 - 0.054 13.1 0.1 0.65 9.5 0.0 2.1 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 GAN05769.1 - 0.064 12.6 0.9 2.1 7.6 0.1 2.9 2 1 0 2 2 2 0 Thiamine monophosphate synthase Alk_phosphatase PF00245.20 GAN05770.1 - 8.3e-102 341.2 0.2 1e-101 340.9 0.2 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAN05770.1 - 0.0073 15.7 0.1 0.019 14.3 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily AAR2 PF05282.11 GAN05771.1 - 1.3e-93 314.3 0.0 1.7e-93 313.8 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein DUF4604 PF15377.6 GAN05771.1 - 0.048 14.1 0.1 0.048 14.1 0.1 1.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) KH_8 PF17903.1 GAN05772.1 - 9.5e-31 105.7 0.2 3.7e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 GAN05772.1 - 0.0011 18.7 0.0 0.0037 17.1 0.0 1.8 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 GAN05772.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 KH domain Glyco_hydro_28 PF00295.17 GAN05773.1 - 2e-58 198.0 23.7 2.6e-58 197.6 23.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MliC PF09864.9 GAN05773.1 - 0.085 12.8 0.3 4.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme End_N_terminal PF12218.8 GAN05773.1 - 0.13 12.0 0.9 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase CcmE PF03100.15 GAN05774.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 CcmE BAR_2 PF10455.9 GAN05776.1 - 5.1e-53 180.1 3.8 1e-52 179.1 3.8 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 GAN05776.1 - 1.6e-23 83.6 4.2 1.2e-22 80.7 4.2 1.9 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAN05776.1 - 3.4e-07 30.2 1.0 8.3e-06 25.7 0.0 2.7 1 1 2 3 3 3 1 BAR domain of APPL family DUF4349 PF14257.6 GAN05776.1 - 0.004 16.6 5.1 0.015 14.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) Spectrin PF00435.21 GAN05776.1 - 0.012 16.1 2.5 0.42 11.1 0.1 2.4 2 0 0 2 2 2 0 Spectrin repeat BRE1 PF08647.11 GAN05776.1 - 0.12 12.5 1.5 0.31 11.2 0.1 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase FliD_N PF02465.18 GAN05776.1 - 0.72 10.6 9.6 0.099 13.3 1.2 3.3 2 2 2 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF2203 PF09969.9 GAN05776.1 - 2.4 8.9 6.2 35 5.1 1.3 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Syntaxin_2 PF14523.6 GAN05776.1 - 2.4 8.6 7.9 0.6 10.5 0.9 2.7 2 1 0 2 2 2 0 Syntaxin-like protein Cyt_bd_oxida_II PF02322.15 GAN05777.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II SIN1 PF05422.12 GAN05777.1 - 0.23 12.0 7.1 0.16 12.5 2.9 2.4 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) SNF2_N PF00176.23 GAN05778.1 - 4.5e-56 190.1 0.0 4.5e-56 190.1 0.0 2.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN05778.1 - 5.5e-18 65.3 0.0 2e-17 63.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 GAN05778.1 - 7.6e-14 51.4 3.5 1.2e-09 37.9 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 GAN05778.1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 4.9 5 1 1 6 6 6 1 Myb-like DNA-binding domain MFS_1 PF07690.16 GAN05779.1 - 2e-27 96.0 29.8 2.5e-27 95.7 29.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA PF00004.29 GAN05781.1 - 2e-39 135.0 0.0 1e-38 132.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN05781.1 - 6.3e-12 45.1 0.1 2.8e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 GAN05781.1 - 0.00015 22.0 0.4 0.035 14.4 0.0 3.3 1 1 2 3 3 3 1 AAA domain RuvB_N PF05496.12 GAN05781.1 - 0.00024 20.9 0.0 0.00065 19.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAN05781.1 - 0.00045 19.5 0.0 0.0013 18.0 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 GAN05781.1 - 0.00051 20.1 0.1 0.0023 18.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN05781.1 - 0.0015 18.9 2.5 0.037 14.4 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 GAN05781.1 - 0.0021 18.6 0.0 0.015 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAN05781.1 - 0.004 16.6 0.0 0.01 15.2 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAN05781.1 - 0.0042 17.4 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 GAN05781.1 - 0.0043 17.2 0.0 0.018 15.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAN05781.1 - 0.0055 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAN05781.1 - 0.0078 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAN05781.1 - 0.008 16.2 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAN05781.1 - 0.0099 15.6 0.0 0.058 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 GAN05781.1 - 0.01 15.2 0.0 0.77 9.1 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 GAN05781.1 - 0.023 14.6 0.0 0.24 11.3 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 GAN05781.1 - 0.042 14.1 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain PELOTA_1 PF15608.6 GAN05781.1 - 0.065 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 PELOTA RNA binding domain AAA_7 PF12775.7 GAN05781.1 - 0.1 12.1 0.2 0.46 10.0 0.1 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 GAN05781.1 - 0.15 11.4 0.3 2.2 7.6 0.1 2.6 2 1 0 3 3 3 0 KaiC CENP-B_dimeris PF09026.10 GAN05781.1 - 0.17 12.3 9.8 0.81 10.1 9.8 2.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ABC_tran PF00005.27 GAN05781.1 - 0.55 10.7 2.7 4.3 7.8 0.0 3.2 2 2 0 2 2 2 0 ABC transporter Pox_RNA_Pol_19 PF05320.12 GAN05781.1 - 0.65 10.0 8.4 12 5.9 6.0 2.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DEAD PF00270.29 GAN05781.1 - 0.68 9.7 2.7 0.61 9.8 0.0 2.4 2 1 1 3 3 2 0 DEAD/DEAH box helicase FYVE PF01363.21 GAN05782.1 - 4.2e-20 71.7 8.2 4.2e-20 71.7 8.2 3.0 3 0 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.16 GAN05782.1 - 0.017 15.3 9.7 0.022 14.9 6.3 2.4 1 1 0 2 2 2 0 FYVE-type zinc finger Rad50_zn_hook PF04423.14 GAN05782.1 - 0.025 14.4 1.1 6.5 6.7 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif TFIIS_C PF01096.18 GAN05782.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.8 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Zn-C2H2_12 PF18112.1 GAN05782.1 - 0.18 12.3 3.2 8 7.0 0.1 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_5 PF14634.6 GAN05782.1 - 0.37 10.8 15.8 14 5.7 9.8 3.6 3 1 0 3 3 3 0 zinc-RING finger domain HypA PF01155.19 GAN05782.1 - 5.8 7.0 11.9 6.5 6.8 3.8 3.0 1 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lipase_GDSL PF00657.22 GAN05784.1 - 1e-16 61.5 0.0 1.5e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN05784.1 - 1.1e-08 35.7 0.0 2.5e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SID-1_RNA_chan PF13965.6 GAN05784.1 - 0.083 11.3 0.9 0.15 10.5 0.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hamartin PF04388.12 GAN05785.1 - 1.8e-23 83.1 38.1 1.2e-22 80.5 38.1 2.5 1 1 0 1 1 1 1 Hamartin protein Mod_r PF07200.13 GAN05785.1 - 0.005 17.0 4.2 0.005 17.0 4.2 5.0 2 1 3 5 5 5 1 Modifier of rudimentary (Mod(r)) protein V-SNARE_C PF12352.8 GAN05785.1 - 0.06 13.6 3.3 0.13 12.6 0.3 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF792 PF05632.11 GAN05785.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) Spc7 PF08317.11 GAN05785.1 - 0.17 10.8 45.1 0.044 12.7 21.8 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 GAN05785.1 - 2.1 5.8 44.1 0.41 8.1 39.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SLATT_6 PF18169.1 GAN05785.1 - 7.5 6.1 7.4 2.2 7.9 1.2 2.6 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Fungal_trans PF04082.18 GAN05786.1 - 2.8e-22 79.0 0.7 2.8e-22 79.0 0.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain G_glu_transpept PF01019.21 GAN05786.1 - 0.011 14.5 4.6 0.025 13.3 4.6 1.5 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Y_phosphatase3 PF13350.6 GAN05788.1 - 8.5e-46 156.8 0.0 2.4e-45 155.3 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAN05788.1 - 2.3e-07 30.5 0.0 1.8e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAN05788.1 - 0.048 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Elicitin PF00964.17 GAN05789.1 - 0.047 13.8 0.1 0.088 12.9 0.1 1.4 1 0 0 1 1 1 0 Elicitin AstE_AspA PF04952.14 GAN05790.1 - 2.4e-37 128.6 0.0 3.5e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.11 GAN05790.1 - 4.1e-23 82.3 0.0 7e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 HutD SET PF00856.28 GAN05791.1 - 9.4e-08 32.6 0.1 9.4e-08 32.6 0.1 3.6 4 1 0 4 4 4 1 SET domain UPF0172 PF03665.13 GAN05791.1 - 1.3 9.0 6.6 0.37 10.8 2.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) UFD1 PF03152.14 GAN05792.1 - 7.8e-46 155.7 0.0 1.7e-45 154.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 GAN05792.1 - 2.8e-07 30.7 0.3 2.8e-07 30.7 0.3 3.1 3 0 0 3 3 3 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A UPF0669 PF17065.5 GAN05792.1 - 0.00026 20.8 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 CDC48_2 PF02933.17 GAN05792.1 - 0.024 14.4 0.0 0.08 12.7 0.0 1.8 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 zf_C2H2_13 PF18508.1 GAN05792.1 - 0.038 13.6 0.9 0.16 11.5 0.9 2.1 1 0 0 1 1 1 0 Zinc finger domain zf_UBZ PF18439.1 GAN05792.1 - 0.096 12.3 0.1 0.096 12.3 0.1 3.4 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger Macoilin PF09726.9 GAN05792.1 - 0.83 8.1 25.6 1.3 7.5 25.6 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 GAN05792.1 - 1 8.1 13.5 1.5 7.5 13.5 1.2 1 0 0 1 1 1 0 Presenilin Response_reg PF00072.24 GAN05793.1 - 7.4e-22 77.6 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Tim17 PF02466.19 GAN05794.1 - 2.5e-32 111.6 6.6 3.1e-32 111.3 6.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bromodomain PF00439.25 GAN05795.1 - 6.2e-17 61.4 1.3 1.8e-16 60.0 1.3 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 GAN05795.1 - 1.9e-10 40.6 0.0 1.1e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 Bromodomain associated VitD-bind_III PF09164.10 GAN05795.1 - 0.27 11.3 3.1 3.9 7.5 0.0 2.8 2 0 0 2 2 2 0 Vitamin D binding protein, domain III TFIIB PF00382.19 GAN05796.1 - 1.1e-41 140.7 0.9 3.7e-21 75.0 0.6 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GAN05796.1 - 9.7e-13 47.4 0.6 2.6e-12 46.1 0.6 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.20 GAN05796.1 - 0.0079 16.0 0.0 0.08 12.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 GAN05796.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Cyclin_C PF02984.19 GAN05796.1 - 0.019 15.0 0.4 0.056 13.5 0.1 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_N PF00134.23 GAN05796.1 - 0.095 12.5 0.2 0.095 12.5 0.2 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain Phage_terminase PF10668.9 GAN05796.1 - 0.18 11.8 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Phage terminase small subunit AEP1 PF17049.5 GAN05797.1 - 0.051 12.7 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 PhoQ_Sensor PF08918.10 GAN05798.1 - 0.034 14.0 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 PhoQ Sensor RhoGAP PF00620.27 GAN05800.1 - 2.9e-43 147.3 0.0 5e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain ADK PF00406.22 GAN05802.1 - 1.3e-47 161.7 0.1 1.6e-47 161.4 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAN05802.1 - 5.7e-39 133.7 0.2 8.3e-39 133.1 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAN05802.1 - 2.3e-12 47.6 0.1 3.3e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAN05802.1 - 1.9e-06 27.7 1.4 0.017 14.8 0.6 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 GAN05802.1 - 6.9e-06 26.3 0.2 7.1e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAN05802.1 - 8.7e-05 21.9 0.0 0.00014 21.2 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin UvrD_C PF13361.6 GAN05802.1 - 0.013 14.9 0.1 0.016 14.6 0.1 1.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain dNK PF01712.19 GAN05802.1 - 0.024 14.5 1.0 0.079 12.8 0.4 1.9 1 1 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 GAN05802.1 - 0.17 12.4 0.3 1 9.9 0.3 2.0 1 1 0 1 1 1 0 ABC transporter dCMP_cyt_deam_1 PF00383.23 GAN05804.1 - 5.5e-12 45.5 1.0 2.1e-11 43.6 1.0 2.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Lip_prot_lig_C PF10437.9 GAN05804.1 - 5.1e-06 26.4 0.0 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus MafB19-deam PF14437.6 GAN05804.1 - 8.1e-06 25.6 2.4 1.3e-05 25.0 0.7 2.2 2 1 0 2 2 2 1 MafB19-like deaminase BPL_LplA_LipB PF03099.19 GAN05804.1 - 1.1e-05 25.3 0.0 5e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Bd3614-deam PF14439.6 GAN05804.1 - 2.3e-05 24.5 0.2 5e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Bd3614-like deaminase HutP PF09021.11 GAN05804.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 HutP Kelch_5 PF13854.6 GAN05805.1 - 9.7e-17 60.6 0.2 2.6e-07 30.4 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 GAN05805.1 - 8.3e-15 54.5 2.0 9.5e-05 22.5 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAN05805.1 - 7.9e-08 32.4 16.4 0.00019 21.6 0.1 6.5 7 0 0 7 7 7 2 Galactose oxidase, central domain BTB PF00651.31 GAN05805.1 - 1.2e-07 32.0 0.2 2.5e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 GAN05805.1 - 1.3e-07 31.5 4.6 0.01 15.8 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN05805.1 - 5.2e-07 29.4 0.0 1.1 9.3 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 GAN05805.1 - 0.00017 21.1 3.0 0.66 9.6 0.0 4.5 4 1 0 4 4 4 2 Kelch motif RAB3GAP2_N PF14655.6 GAN05805.1 - 0.035 13.4 2.9 0.53 9.5 0.2 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3043 PF11241.8 GAN05805.1 - 1.2 9.2 2.9 2.9 7.9 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Aminotran_1_2 PF00155.21 GAN05806.1 - 1.2e-42 146.5 0.0 1.7e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 GAN05806.1 - 3.2e-37 125.9 21.8 2.7e-05 24.9 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05806.1 - 4.4e-17 62.2 5.0 0.00018 21.7 0.0 6.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN05806.1 - 4e-07 29.3 2.1 0.12 11.3 0.1 4.4 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAN05806.1 - 1.3e-05 24.7 1.6 0.0057 16.0 0.1 3.3 2 1 1 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 GAN05806.1 - 0.00019 20.1 0.1 0.019 13.5 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 GAN05806.1 - 0.00054 18.8 3.7 1.7 7.3 0.2 3.7 1 1 2 3 3 3 2 Nup133 N terminal like BBS2_Mid PF14783.6 GAN05806.1 - 0.00093 19.2 0.0 6.9 6.8 0.0 4.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Cys_Met_Meta_PP PF01053.20 GAN05806.1 - 0.005 15.4 0.0 0.0081 14.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GAN05806.1 - 0.03 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase VID27 PF08553.10 GAN05806.1 - 0.045 12.8 0.1 0.27 10.2 0.0 2.0 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain PQQ_3 PF13570.6 GAN05806.1 - 0.056 14.0 0.4 1.4 9.5 0.1 3.2 3 1 1 4 4 3 0 PQQ-like domain NodS PF05401.11 GAN05806.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) ADH_N PF08240.12 GAN05807.1 - 1.4e-25 89.2 8.9 2.8e-25 88.3 8.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN05807.1 - 1.1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAN05807.1 - 7.8e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAN05807.1 - 0.00044 19.7 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAN05807.1 - 0.00072 20.6 0.0 0.001 20.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 GAN05807.1 - 0.0078 16.0 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NAD_binding_2 PF03446.15 GAN05807.1 - 0.018 15.2 0.1 0.03 14.5 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4434 PF14488.6 GAN05807.1 - 0.036 14.1 0.3 0.13 12.2 0.0 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4434) 3HCDH_N PF02737.18 GAN05807.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sin3a_C PF16879.5 GAN05808.1 - 9.3e-63 212.6 9.6 9.3e-63 212.6 9.6 3.2 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 GAN05808.1 - 8.6e-42 141.0 19.9 3.7e-18 65.4 0.0 4.8 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAN05808.1 - 3.2e-41 139.3 1.0 1.2e-40 137.5 1.0 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor ResIII PF04851.15 GAN05808.1 - 0.81 9.7 4.8 0.59 10.1 0.5 2.8 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Baculo_PP31 PF05311.11 GAN05808.1 - 1.4 8.3 9.7 0.14 11.7 3.3 2.5 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) XendoU PF09412.10 GAN05808.1 - 1.6 7.9 6.8 0.31 10.2 1.0 2.5 3 0 0 3 3 3 0 Endoribonuclease XendoU PRP9_N PF16958.5 GAN05808.1 - 1.6 8.7 12.2 36 4.3 0.1 4.0 2 1 0 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF5327 PF17261.2 GAN05808.1 - 1.7 9.5 6.9 0.21 12.4 1.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5327) APCDDC PF14921.6 GAN05810.1 - 0.15 11.5 1.6 0.15 11.5 1.6 1.0 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 RRM_1 PF00076.22 GAN05811.1 - 1.7e-91 300.1 0.6 9.2e-24 83.1 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAN05811.1 - 9.6e-31 105.8 1.0 4.8e-30 103.5 0.9 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAN05811.1 - 3.2e-15 55.8 0.0 0.0071 15.9 0.0 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN05811.1 - 2.4e-08 34.0 0.1 0.18 11.9 0.0 5.1 3 1 1 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 GAN05811.1 - 2.2e-06 27.4 0.0 0.0036 17.1 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAN05811.1 - 6.9e-06 26.0 0.6 8.6 6.5 0.0 4.8 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 GAN05811.1 - 0.00027 20.8 0.0 28 4.5 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4523) RRM_3 PF08777.11 GAN05811.1 - 0.00028 20.9 2.7 2.2 8.4 0.7 4.3 4 0 0 4 4 4 1 RNA binding motif SET_assoc PF11767.8 GAN05811.1 - 0.00035 20.1 0.1 2.5 7.8 0.0 4.1 3 1 0 4 4 4 1 Histone lysine methyltransferase SET associated YflT PF11181.8 GAN05811.1 - 0.0031 18.0 1.1 1.3 9.6 1.3 3.0 2 0 0 2 2 2 1 Heat induced stress protein YflT Limkain-b1 PF11608.8 GAN05811.1 - 0.0049 16.9 1.6 3.1 7.9 0.1 3.8 4 0 0 4 4 4 1 Limkain b1 OB_RNB PF08206.11 GAN05811.1 - 0.0051 16.5 3.5 3.2 7.5 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain PHM7_cyt PF14703.6 GAN05811.1 - 0.34 11.1 5.1 49 4.1 0.0 5.1 5 2 1 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter Mito_carr PF00153.27 GAN05812.1 - 1.4e-62 207.7 1.6 9e-21 73.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN05812.1 - 0.0042 16.3 0.1 1.9 7.5 0.1 2.6 2 0 0 2 2 2 2 Gammaproteobacterial serine protease PACT_coil_coil PF10495.9 GAN05814.1 - 0.12 13.0 0.1 0.4 11.3 0.1 1.9 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Exonuc_VII_L PF02601.15 GAN05814.1 - 0.22 11.1 4.6 0.25 10.9 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CoA_binding PF02629.19 GAN05815.1 - 2e-31 108.5 1.6 3.8e-31 107.6 0.7 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 GAN05815.1 - 6.1e-22 78.1 0.1 1.2e-21 77.1 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAN05815.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAN05815.1 - 3.9e-05 24.1 0.1 0.00011 22.7 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain PAF-AH_p_II PF03403.13 GAN05816.1 - 5.8e-67 225.8 0.0 4.4e-66 222.9 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GAN05816.1 - 8.8e-13 47.7 0.0 2.3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GAN05816.1 - 4.5e-08 32.6 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAN05816.1 - 1.2e-07 31.4 0.0 4.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAN05816.1 - 7.8e-05 22.4 0.2 0.00076 19.2 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 GAN05816.1 - 9.4e-05 21.6 0.0 0.00089 18.4 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 GAN05816.1 - 0.00015 22.4 0.0 0.00023 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAN05816.1 - 0.00054 19.6 0.0 0.0015 18.1 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 GAN05816.1 - 0.0035 17.1 0.0 0.31 10.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family RRM_1 PF00076.22 GAN05817.1 - 1.3e-18 66.6 0.0 1.6e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GAN05818.1 - 1.6e-18 66.3 0.0 2.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN05818.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAN05818.1 - 0.00095 19.2 0.6 0.0046 17.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif SUIM_assoc PF16619.5 GAN05818.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 5.4 4 3 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 RRM_3 PF08777.11 GAN05818.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 2.4 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 GAN05818.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 GAN05818.1 - 0.026 14.1 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 GAN05819.1 - 1.2e-42 145.6 0.1 2.4e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN05819.1 - 1.5e-25 89.7 0.0 1.4e-22 80.2 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAN05819.1 - 1.2e-10 41.6 0.1 3.2e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAN05819.1 - 0.0026 18.0 0.9 0.2 11.9 0.4 3.1 1 1 1 2 2 2 1 AAA domain T4SS-DNA_transf PF02534.14 GAN05819.1 - 0.078 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Sulfotransfer_4 PF17784.1 GAN05820.1 - 6e-57 192.9 0.0 7.4e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain AMP-binding PF00501.28 GAN05822.1 - 2.7e-84 283.2 0.0 3.3e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN05822.1 - 6.1e-18 65.6 0.1 1.2e-17 64.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RTX_C PF08339.10 GAN05822.1 - 0.047 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain GH3 PF03321.13 GAN05822.1 - 0.12 11.3 0.0 0.54 9.0 0.0 1.8 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Fungal_trans PF04082.18 GAN05823.1 - 3.7e-15 55.7 3.4 3.7e-15 55.7 3.4 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN05823.1 - 3.2e-07 30.3 10.3 6e-07 29.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP14 PF02290.15 GAN05823.1 - 0.042 14.2 0.1 0.24 11.8 0.1 2.4 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Kelch_5 PF13854.6 GAN05824.1 - 7.5e-22 76.9 8.7 1e-05 25.4 0.6 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 GAN05824.1 - 1.4e-16 59.8 13.2 4e-06 26.3 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAN05824.1 - 7.1e-16 57.9 11.0 0.0016 18.4 0.2 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN05824.1 - 5.5e-15 55.0 8.6 0.0017 18.6 0.0 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 GAN05824.1 - 9.6e-12 44.4 7.5 0.0074 16.2 0.2 6.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAN05824.1 - 2.3e-08 34.1 14.2 0.00017 21.8 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain ANAPC_CDC26 PF10471.9 GAN05824.1 - 3.3e-06 27.8 1.1 3.3e-06 27.8 1.1 4.6 5 1 0 5 5 5 1 Anaphase-promoting complex APC subunit CDC26 CotH PF08757.11 GAN05825.1 - 4e-36 125.2 0.5 7e-36 124.4 0.5 1.3 1 0 0 1 1 1 1 CotH kinase protein GHMP_kinases_N PF00288.26 GAN05826.1 - 3.4e-05 24.0 0.0 8.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAN05826.1 - 0.015 15.6 0.1 0.036 14.4 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal ADH_zinc_N PF00107.26 GAN05827.1 - 1.2e-24 86.7 0.1 2.1e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN05827.1 - 7.3e-17 62.7 0.0 1.3e-16 61.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN05827.1 - 1.9e-09 37.4 0.0 1.4e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tetraspanin PF00335.20 GAN05829.1 - 0.00024 20.9 3.8 0.00024 20.9 3.8 2.0 1 1 1 2 2 2 2 Tetraspanin family DUF2754 PF10953.8 GAN05829.1 - 0.011 15.9 0.2 0.018 15.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Sulfate_transp PF00916.20 GAN05829.1 - 0.021 13.6 0.2 0.025 13.3 0.2 1.1 1 0 0 1 1 1 0 Sulfate permease family DUF4229 PF14012.6 GAN05829.1 - 0.099 12.8 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Aim19 PF10315.9 GAN05830.1 - 1.4e-24 86.6 7.7 5.5e-24 84.7 7.7 1.8 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Atg14 PF10186.9 GAN05831.1 - 2.3 7.2 7.7 3.1 6.8 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nop25 PF09805.9 GAN05832.1 - 5.8e-24 85.1 19.3 9.9e-24 84.4 19.3 1.3 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) CNDH2_C PF16858.5 GAN05832.1 - 0.51 10.2 15.5 0.59 10.0 15.5 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 GAN05832.1 - 9.5 5.5 27.6 5 6.4 6.2 2.1 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) NFACT-R_1 PF05670.13 GAN05833.1 - 1.2e-37 128.8 0.0 1.8e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NPIP PF06409.11 GAN05833.1 - 0.77 8.8 4.9 1.1 8.3 4.9 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Pyrophosphatase PF00719.19 GAN05834.1 - 6.8e-58 195.0 0.9 9.2e-58 194.6 0.9 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase ATG16 PF08614.11 GAN05835.1 - 8.2e-43 147.0 34.6 8.2e-43 147.0 34.6 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 GAN05835.1 - 4.2e-38 128.7 19.3 3e-06 27.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05835.1 - 1.6e-17 63.6 4.1 0.0011 19.2 0.0 7.0 2 1 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN05835.1 - 1e-11 45.1 0.1 0.0073 16.2 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN05835.1 - 2.5e-06 26.7 0.6 0.2 10.6 0.0 3.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAN05835.1 - 9.2e-05 21.1 0.0 0.0018 16.9 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 GAN05835.1 - 0.0029 17.0 0.1 1.7 7.9 0.0 3.4 2 1 1 3 3 3 1 WD40-like domain PQQ PF01011.21 GAN05835.1 - 0.0048 16.7 1.0 5.4 7.1 0.1 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 GAN05835.1 - 0.012 15.2 0.6 1.8 8.0 0.5 2.9 1 1 0 1 1 1 0 PQQ-like domain DUF5046 PF16465.5 GAN05835.1 - 0.027 13.9 0.1 0.16 11.4 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5046) PD40 PF07676.12 GAN05835.1 - 0.069 13.1 0.2 12 6.0 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 GAN05835.1 - 0.076 12.8 0.1 13 5.4 0.0 2.4 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain CALCOCO1 PF07888.11 GAN05835.1 - 1 8.1 35.3 2.1 7.1 35.1 1.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 GAN05835.1 - 1.4 8.3 30.0 2.4 7.6 30.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 FUSC PF04632.12 GAN05835.1 - 3 6.2 9.4 4.2 5.8 9.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF16 PF01519.16 GAN05835.1 - 4.3 7.9 26.6 0.069 13.6 12.8 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 FUSC_2 PF13515.6 GAN05837.1 - 6.3e-18 65.1 11.8 6.3e-18 65.1 11.8 2.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAN05837.1 - 1e-16 60.7 4.7 1.2e-14 53.8 0.1 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 GAN05837.1 - 1.7e-13 51.0 3.9 6.1e-13 49.1 1.7 2.8 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 GAN05837.1 - 4.5e-12 45.8 9.0 4.8e-10 39.1 0.1 2.7 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 GAN05837.1 - 7.5e-11 41.5 2.5 7.5e-11 41.5 2.5 3.8 2 1 0 2 2 2 1 Aluminium activated malate transporter PyrI_C PF02748.15 GAN05837.1 - 0.04 13.8 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Pkinase PF00069.25 GAN05838.1 - 2.9e-47 161.3 0.0 4.9e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05838.1 - 2.5e-20 72.9 0.0 4.1e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN05838.1 - 3.1e-06 27.3 0.0 6.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN05838.1 - 7.4e-05 22.2 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN05838.1 - 0.0036 16.3 0.0 0.0077 15.2 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Aconitase PF00330.20 GAN05839.1 - 5.7e-154 513.5 0.0 7.5e-154 513.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAN05839.1 - 8.8e-42 142.5 0.0 1.8e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 GAN05839.1 - 0.099 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MCM PF00493.23 GAN05840.1 - 5e-98 326.7 0.0 7.5e-98 326.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAN05840.1 - 3.7e-35 120.5 0.4 6.4e-35 119.7 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAN05840.1 - 2.5e-30 104.7 1.1 5.3e-30 103.7 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAN05840.1 - 3.5e-16 59.7 3.6 5e-16 59.2 1.4 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 GAN05840.1 - 3.1e-08 33.7 0.0 8.9e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAN05840.1 - 1e-06 28.3 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAN05840.1 - 0.0002 21.2 0.0 0.018 14.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAN05840.1 - 0.00082 19.1 0.3 1.8 8.3 0.0 3.3 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_16 PF13191.6 GAN05840.1 - 0.0011 19.3 0.1 0.012 16.1 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain GATA PF00320.27 GAN05841.1 - 3.5e-16 58.5 2.2 7.5e-16 57.4 2.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 GAN05841.1 - 2.1e-14 53.0 1.1 4.6e-14 51.9 1.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) eIF-3_zeta PF05091.12 GAN05842.1 - 3.3e-207 689.6 1.5 3.7e-207 689.4 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 GAN05842.1 - 0.01 15.4 0.0 0.7 9.4 0.0 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated gene protein 2 C-terminus Snapin_Pallidin PF14712.6 GAN05843.1 - 1.9e-13 50.6 0.0 2.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Flagellin_C PF00700.21 GAN05843.1 - 0.0087 16.4 0.4 0.72 10.3 0.0 2.2 2 0 0 2 2 2 1 Bacterial flagellin C-terminal helical region HAUS2 PF15003.6 GAN05843.1 - 0.066 12.9 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Fusion_gly PF00523.18 GAN05843.1 - 0.084 11.1 0.0 0.099 10.9 0.0 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 TMF_DNA_bd PF12329.8 GAN05843.1 - 0.11 12.5 2.7 7.7 6.6 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phosphorylase PF00343.20 GAN05844.1 - 0 1042.6 0.0 0 1042.3 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-RVT PF13966.6 GAN05848.1 - 0.0078 16.9 0.5 0.011 16.4 0.5 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Corona_S2 PF01601.16 GAN05849.1 - 0.036 12.6 8.1 0.053 12.0 1.3 2.6 3 0 0 3 3 3 0 Coronavirus S2 glycoprotein Pro_sub2 PF18513.1 GAN05849.1 - 0.16 12.2 2.6 2.1 8.6 0.0 2.9 3 0 0 3 3 3 0 Prodomain subtilisin 2 BLOC1_2 PF10046.9 GAN05849.1 - 2.6 8.4 27.5 0.82 10.0 5.0 4.8 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 GAN05849.1 - 5.8 7.0 27.2 0.72 9.9 2.4 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) zf-C2H2 PF00096.26 GAN05850.1 - 5.7e-11 42.2 7.0 3e-05 24.2 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN05850.1 - 9.6e-08 32.1 12.6 0.0004 20.7 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN05850.1 - 1.8e-06 28.3 6.7 0.022 15.6 1.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 GAN05850.1 - 0.00036 20.2 0.6 0.042 13.6 0.2 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 GAN05850.1 - 0.00084 19.6 0.5 0.0031 17.8 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAN05850.1 - 0.0016 18.4 2.9 1 9.4 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 GAN05850.1 - 0.0042 17.4 1.8 0.018 15.4 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 GAN05850.1 - 0.019 15.4 0.2 0.7 10.4 0.1 2.6 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 GAN05850.1 - 0.055 13.3 3.8 0.097 12.4 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type PAP1 PF08601.10 GAN05850.1 - 0.43 10.3 6.7 0.57 9.9 6.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 zf-BED PF02892.15 GAN05850.1 - 0.52 10.4 4.2 14 5.8 0.1 2.7 2 0 0 2 2 2 0 BED zinc finger SR-25 PF10500.9 GAN05850.1 - 2.5 7.6 7.4 3.9 7.0 7.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.7 GAN05851.1 - 1.4e-05 24.9 0.2 3.5e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN05851.1 - 0.0061 16.4 0.3 0.016 15.1 0.3 1.7 1 0 0 1 1 1 1 F-box domain Nas2_N PF18265.1 GAN05851.1 - 0.059 13.3 0.5 4.1 7.4 0.0 3.2 2 1 1 3 3 3 0 Nas2 N_terminal domain Polyketide_cyc PF03364.20 GAN05852.1 - 4.1e-08 33.5 0.1 1e-07 32.2 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAN05852.1 - 1.6e-06 28.5 0.0 2.7e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Tropomyosin_1 PF12718.7 GAN05853.1 - 1.5e-30 106.2 39.8 1.5e-30 106.2 39.8 1.7 1 1 1 2 2 2 1 Tropomyosin like Tropomyosin PF00261.20 GAN05853.1 - 3.4e-06 26.6 40.8 1.6e-05 24.4 40.8 2.1 1 1 0 1 1 1 1 Tropomyosin MscS_porin PF12795.7 GAN05853.1 - 1.7e-05 24.5 22.4 1.7e-05 24.5 22.4 2.0 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 GAN05853.1 - 2.7e-05 24.2 27.0 0.0038 17.2 11.6 2.1 1 1 1 2 2 2 2 Laminin Domain II CENP-F_leu_zip PF10473.9 GAN05853.1 - 5.8e-05 23.1 41.4 0.00043 20.3 14.2 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 GAN05853.1 - 0.00014 20.3 38.1 0.00043 18.6 24.1 2.0 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil HOOK PF05622.12 GAN05853.1 - 0.0002 19.7 36.6 0.00067 17.9 17.7 2.0 1 1 1 2 2 2 2 HOOK protein BST2 PF16716.5 GAN05853.1 - 0.00036 21.0 32.3 0.011 16.3 9.0 2.3 1 1 0 2 2 2 2 Bone marrow stromal antigen 2 ABC_tran_CTD PF16326.5 GAN05853.1 - 0.00044 20.5 40.6 0.0065 16.7 10.4 3.3 2 1 1 3 3 3 1 ABC transporter C-terminal domain Fez1 PF06818.15 GAN05853.1 - 0.00044 20.8 29.9 0.00055 20.4 29.3 1.5 1 1 0 1 1 1 1 Fez1 DUF1664 PF07889.12 GAN05853.1 - 0.00095 19.2 21.2 0.036 14.1 4.8 3.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 GAN05853.1 - 0.0016 18.7 36.0 0.16 12.2 18.1 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) CENP-H PF05837.12 GAN05853.1 - 0.0026 18.1 28.5 0.075 13.4 7.9 2.3 1 1 1 2 2 2 2 Centromere protein H (CENP-H) GAS PF13851.6 GAN05853.1 - 0.0028 17.1 38.9 0.0037 16.6 37.6 1.8 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 GAN05853.1 - 0.0029 17.8 29.5 0.1 12.8 9.6 2.3 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein TPR_MLP1_2 PF07926.12 GAN05853.1 - 0.0041 17.2 39.1 0.071 13.2 12.9 2.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 GAN05853.1 - 0.0045 15.9 39.2 0.16 10.8 14.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein EzrA PF06160.12 GAN05853.1 - 0.0054 15.0 35.0 0.039 12.1 35.0 1.9 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA ADIP PF11559.8 GAN05853.1 - 0.0054 16.8 34.0 0.34 11.0 13.4 2.8 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 GAN05853.1 - 0.0071 16.4 39.0 0.074 13.1 13.4 2.6 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 GAN05853.1 - 0.0086 16.5 33.8 0.61 10.5 8.0 4.6 3 2 1 4 4 4 2 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 GAN05853.1 - 0.01 15.2 24.6 0.012 15.0 24.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 GAN05853.1 - 0.013 15.6 39.8 0.61 10.2 16.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TRAF_BIRC3_bd PF16673.5 GAN05853.1 - 0.014 15.2 3.1 0.014 15.2 3.1 3.1 2 1 1 4 4 3 0 TNF receptor-associated factor BIRC3 binding domain MAD PF05557.13 GAN05853.1 - 0.015 13.7 36.6 0.018 13.5 36.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Lebercilin PF15619.6 GAN05853.1 - 0.015 15.0 38.0 0.11 12.2 13.1 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Lectin_N PF03954.14 GAN05853.1 - 0.015 15.0 5.0 0.015 15.0 5.0 2.9 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain CtIP_N PF10482.9 GAN05853.1 - 0.019 15.0 6.9 0.019 15.0 6.9 2.9 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain WXG100 PF06013.12 GAN05853.1 - 0.024 14.9 15.2 0.19 12.0 2.2 4.0 2 2 1 3 3 3 0 Proteins of 100 residues with WXG FlxA PF14282.6 GAN05853.1 - 0.026 14.5 28.8 0.14 12.1 8.6 3.2 1 1 2 3 3 3 0 FlxA-like protein PspA_IM30 PF04012.12 GAN05853.1 - 0.028 14.0 30.9 0.035 13.7 29.2 1.9 1 1 0 1 1 1 0 PspA/IM30 family KxDL PF10241.9 GAN05853.1 - 0.034 14.4 24.8 0.33 11.2 2.1 3.7 1 1 3 4 4 4 0 Uncharacterized conserved protein Uso1_p115_C PF04871.13 GAN05853.1 - 0.04 14.3 42.1 0.43 11.0 24.1 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 GAN05853.1 - 0.046 14.2 46.1 0.81 10.2 26.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec34 PF04136.15 GAN05853.1 - 0.058 13.3 22.3 0.22 11.4 9.3 2.2 2 0 0 2 2 2 0 Sec34-like family DUF3450 PF11932.8 GAN05853.1 - 0.064 12.5 30.3 0.09 12.1 11.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 GAN05853.1 - 0.072 13.3 24.0 0.072 13.3 16.0 2.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 GAN05853.1 - 0.075 12.8 33.5 0.38 10.5 12.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Aromatic_hydrox PF11723.8 GAN05853.1 - 0.077 12.5 1.4 0.11 12.0 1.4 1.3 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase BLOC1_2 PF10046.9 GAN05853.1 - 0.11 12.8 28.8 1.2 9.5 6.1 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HemX PF04375.14 GAN05853.1 - 0.11 11.7 26.0 0.51 9.6 9.6 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 GAN05853.1 - 0.12 11.4 27.7 0.065 12.3 8.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4164 PF13747.6 GAN05853.1 - 0.12 12.6 27.4 0.13 12.6 8.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF16 PF01519.16 GAN05853.1 - 0.15 12.6 30.3 1 9.9 14.0 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 Phage_GPO PF05929.11 GAN05853.1 - 0.19 11.3 22.9 0.14 11.7 12.7 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Taxilin PF09728.9 GAN05853.1 - 0.2 10.8 36.8 0.14 11.3 8.9 2.8 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF4200 PF13863.6 GAN05853.1 - 0.24 11.8 40.5 2.1 8.8 20.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 GAN05853.1 - 0.24 8.9 32.6 0.28 8.7 32.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 GAN05853.1 - 0.24 11.9 21.3 1.5 9.3 7.9 2.9 1 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 GAN05853.1 - 0.26 11.9 25.5 0.72 10.5 7.1 3.2 1 1 2 3 3 3 0 SlyX BRE1 PF08647.11 GAN05853.1 - 0.27 11.3 39.8 0.26 11.4 15.2 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 GAN05853.1 - 0.28 10.6 42.3 0.25 10.8 13.5 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DASH_Hsk3 PF08227.11 GAN05853.1 - 0.3 11.5 11.3 11 6.4 0.1 4.6 4 1 1 5 5 5 0 DASH complex subunit Hsk3 like Phage_GP20 PF06810.11 GAN05853.1 - 0.41 10.5 40.8 1.9 8.3 12.3 3.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.8 GAN05853.1 - 0.43 10.6 48.7 3.1 7.9 12.6 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 GAN05853.1 - 0.44 9.1 32.3 0.86 8.2 32.3 1.5 1 1 0 1 1 1 0 AAA domain Jnk-SapK_ap_N PF09744.9 GAN05853.1 - 0.47 10.7 37.9 4.4 7.5 25.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 GAN05853.1 - 0.47 10.9 46.1 0.25 11.8 13.3 3.9 1 1 2 3 3 3 0 Cell division protein ZapB Rootletin PF15035.6 GAN05853.1 - 0.48 10.4 31.8 0.038 14.0 13.6 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion GIT_CC PF16559.5 GAN05853.1 - 0.65 9.9 14.0 3 7.8 1.9 3.2 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Syntaxin-6_N PF09177.11 GAN05853.1 - 0.72 10.5 26.2 0.37 11.4 5.3 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Sec2p PF06428.11 GAN05853.1 - 0.73 9.8 36.7 0.56 10.2 13.0 4.3 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF2408 PF10303.9 GAN05853.1 - 0.77 10.3 25.9 0.45 11.1 11.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) SHE3 PF17078.5 GAN05853.1 - 0.98 9.1 31.9 49 3.5 31.8 2.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF812 PF05667.11 GAN05853.1 - 1 8.2 37.2 2.1 7.1 37.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 GAN05853.1 - 1 10.0 28.5 1.2 9.8 8.3 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 GAN05853.1 - 1.1 9.5 38.8 2.7 8.3 4.6 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 GAN05853.1 - 1.2 9.4 38.2 0.095 12.9 8.8 3.9 2 2 2 4 4 4 0 Haemolysin XhlA Occludin_ELL PF07303.13 GAN05853.1 - 1.2 9.8 22.6 2.1 9.1 10.9 2.4 1 1 1 2 2 2 0 Occludin homology domain MCPsignal PF00015.21 GAN05853.1 - 1.3 8.8 14.6 0.46 10.3 3.4 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain T3SSipB PF16535.5 GAN05853.1 - 1.5 9.3 22.5 15 6.1 5.6 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB Nup54 PF13874.6 GAN05853.1 - 1.6 8.9 24.7 2.7 8.1 9.8 2.3 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4201 PF13870.6 GAN05853.1 - 2.1 8.1 32.9 8 6.1 15.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 GAN05853.1 - 2.5 8.3 37.1 16 5.8 16.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HrpB7 PF09486.10 GAN05853.1 - 2.6 8.4 21.8 3.8 7.9 15.0 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4250 PF14056.6 GAN05853.1 - 3.1 7.8 9.4 1 9.4 0.1 3.5 3 1 1 4 4 3 0 Domain of unknown function (DUF4250) TolA_bind_tri PF16331.5 GAN05853.1 - 3.2 7.9 18.5 2.2 8.4 2.9 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation PRKG1_interact PF15898.5 GAN05853.1 - 3.3 8.7 32.2 1.5 9.7 15.3 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF641 PF04859.12 GAN05853.1 - 3.8 7.9 24.7 4.9 7.5 7.1 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 GAN05853.1 - 4.2 6.5 28.6 3.8 6.7 11.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein KELK PF15796.5 GAN05853.1 - 4.2 7.9 39.4 2.5 8.6 8.8 3.3 2 1 2 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase IFT57 PF10498.9 GAN05853.1 - 4.6 6.1 31.2 6.7 5.6 16.1 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 GAN05853.1 - 4.7 6.6 34.8 9.1 5.6 34.8 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF2203 PF09969.9 GAN05853.1 - 4.8 7.9 23.2 6.4 7.5 7.3 2.6 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) GCN5L1 PF06320.13 GAN05853.1 - 4.9 7.3 23.3 1 9.5 5.4 2.4 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF2911 PF11138.8 GAN05853.1 - 5.1 6.9 11.9 1.8 8.4 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2911) COG2 PF06148.11 GAN05853.1 - 5.2 7.2 24.1 7.4 6.7 6.3 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CLZ PF16526.5 GAN05853.1 - 5.5 7.4 32.8 0.23 11.8 4.2 4.5 1 1 2 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec8_exocyst PF04048.14 GAN05853.1 - 5.5 6.9 19.4 12 5.8 3.7 3.0 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.19 GAN05853.1 - 6.4 4.6 27.3 1.3 6.8 11.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CC2-LZ PF16516.5 GAN05853.1 - 6.7 7.1 33.8 0.38 11.1 8.3 3.1 1 1 1 2 2 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CCM2_C PF16545.5 GAN05853.1 - 7.7 7.1 7.2 13 6.4 1.1 2.3 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Spectrin PF00435.21 GAN05853.1 - 8.5 6.9 29.4 6.9 7.2 10.2 2.5 1 1 1 2 2 2 0 Spectrin repeat baeRF_family2 PF18844.1 GAN05853.1 - 9.8 6.2 14.3 2.5 8.2 1.5 2.9 1 1 2 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 Ribosomal_L37ae PF01780.19 GAN05854.1 - 2.6e-41 139.6 13.0 2.9e-41 139.5 13.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 GAN05854.1 - 0.00097 19.2 3.2 0.0014 18.7 3.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 GAN05854.1 - 0.0015 18.5 1.8 0.0023 17.9 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 GAN05854.1 - 0.014 15.4 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 GAN05854.1 - 0.022 14.4 2.9 2.9 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 GAN05854.1 - 0.036 14.0 3.2 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 GAN05854.1 - 0.12 12.7 2.9 4.5 7.7 3.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 GAN05854.1 - 0.93 9.6 5.6 4 7.5 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 GAN05854.1 - 4.2 8.0 7.3 2.4 8.7 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Kelch_5 PF13854.6 GAN05855.1 - 6.2e-27 93.1 3.2 2.7e-06 27.2 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 GAN05855.1 - 4.9e-23 80.6 8.2 5.3e-06 26.5 0.1 5.6 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAN05855.1 - 1.2e-22 79.6 7.4 1.5e-07 31.3 0.6 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN05855.1 - 1.4e-17 63.5 2.4 0.011 16.0 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN05855.1 - 5.7e-16 57.8 0.1 0.0061 16.5 0.0 5.2 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 GAN05855.1 - 8.2e-13 48.6 0.1 1.6e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 GAN05855.1 - 1e-10 41.0 0.2 0.0027 17.2 0.1 4.4 4 0 0 4 4 4 3 Kelch motif BACK PF07707.15 GAN05855.1 - 0.0019 18.3 0.1 0.006 16.7 0.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Ribosomal_L29 PF00831.23 GAN05856.1 - 5.5e-14 51.9 2.1 5.5e-14 51.9 2.1 2.0 1 1 1 2 2 2 1 Ribosomal L29 protein UPF0231 PF06062.11 GAN05856.1 - 0.053 13.8 0.5 0.38 11.0 0.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Ribosomal_S9 PF00380.19 GAN05856.1 - 0.063 13.8 3.5 0.097 13.2 3.5 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 CDC45 PF02724.14 GAN05857.1 - 0.016 13.5 21.5 0.019 13.3 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAN05857.1 - 0.031 12.5 24.9 0.034 12.4 24.9 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 GAN05857.1 - 0.2 11.8 1.6 0.23 11.6 1.6 1.2 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 GAN05857.1 - 1.8 7.7 4.3 1.9 7.6 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GAN05857.1 - 2.2 7.0 6.8 2.3 6.9 6.8 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 GAN05857.1 - 3.1 7.0 24.9 4.7 6.5 24.9 1.2 1 0 0 1 1 1 0 NOA36 protein Connexin PF00029.19 GAN05857.1 - 6.1 6.5 6.2 8.5 6.1 6.2 1.2 1 0 0 1 1 1 0 Connexin SDA1 PF05285.12 GAN05857.1 - 6.4 6.1 31.0 11 5.3 31.0 1.4 1 0 0 1 1 1 0 SDA1 Roughex PF06020.11 GAN05857.1 - 7.9 5.5 18.1 9.9 5.2 18.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CobT PF06213.12 GAN05857.1 - 8.1 5.7 20.7 11 5.3 20.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 GAN05857.1 - 8.5 6.1 25.2 10 5.8 24.6 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein V_ATPase_I PF01496.19 GAN05857.1 - 9.6 4.0 10.1 12 3.7 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP90 PF00183.18 GAN05858.1 - 7e-232 770.9 22.8 8.4e-232 770.6 22.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAN05858.1 - 6.3e-10 39.5 0.1 4.2e-09 36.9 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAN05858.1 - 5.4e-09 36.0 0.5 2.8e-08 33.7 0.5 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 GAN05858.1 - 0.2 11.7 1.5 0.31 11.0 0.0 2.0 3 0 0 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN DUF45 PF01863.17 GAN05858.1 - 6.2 6.8 12.2 1.9 8.5 3.8 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF45 MFS_1_like PF12832.7 GAN05859.1 - 6.6e-44 150.3 13.5 8.9e-44 149.9 13.5 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAN05859.1 - 4.2e-22 78.5 18.3 1.2e-20 73.7 2.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAN05859.1 - 1.6e-12 47.1 17.0 1.1e-11 44.4 10.9 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter TPPK_C PF12555.8 GAN05859.1 - 0.02 14.9 3.0 0.067 13.2 3.0 1.9 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal FUN14 PF04930.15 GAN05859.1 - 0.31 11.5 3.3 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 FUN14 family NDUF_B12 PF08122.12 GAN05859.1 - 0.68 10.0 8.5 6.5 6.9 0.1 3.8 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Methyltransf_11 PF08241.12 GAN05860.1 - 8e-14 52.1 0.0 2.1e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN05860.1 - 3.2e-13 50.2 0.0 8.9e-13 48.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN05860.1 - 6.3e-10 39.0 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05860.1 - 8.2e-10 38.8 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN05860.1 - 2.8e-07 31.2 0.0 5.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05860.1 - 6.6e-07 28.9 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 GAN05860.1 - 3.1e-05 23.7 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 GAN05860.1 - 0.00055 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAN05860.1 - 0.00065 19.2 0.0 0.0019 17.7 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 GAN05860.1 - 0.0049 16.2 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 GAN05860.1 - 0.093 12.6 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.18 GAN05860.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Mucin PF01456.17 GAN05860.1 - 2.1 8.4 12.8 5.9 6.9 5.2 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Acyl-CoA_dh_1 PF00441.24 GAN05861.1 - 9.8e-49 165.4 2.9 1.7e-48 164.7 2.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAN05861.1 - 2.2e-28 98.3 0.4 5.3e-28 97.1 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAN05861.1 - 1.5e-25 90.1 0.2 3e-25 89.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAN05861.1 - 1e-17 64.6 1.0 1.7e-17 63.9 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAN05861.1 - 0.00013 21.7 0.2 0.00035 20.3 0.2 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.25 GAN05862.1 - 7.6e-63 212.3 0.1 1.3e-62 211.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain GTP_EFTU PF00009.27 GAN05862.1 - 2.1e-45 154.7 0.0 3.6e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Pkinase_Tyr PF07714.17 GAN05862.1 - 1.4e-33 116.3 0.1 2.6e-33 115.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GTP_EFTU_D3 PF03143.17 GAN05862.1 - 1.3e-22 80.2 0.1 5.4e-22 78.2 0.0 2.2 2 0 0 2 2 1 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 GAN05862.1 - 2.3e-13 50.2 4.4 6.3e-13 48.8 4.4 1.7 1 0 0 1 1 1 1 HBS1 N-terminus Kinase-like PF14531.6 GAN05862.1 - 4.1e-08 32.9 0.0 1.2e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like MMR_HSR1 PF01926.23 GAN05862.1 - 2.7e-05 24.2 0.0 0.00053 20.0 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAN05862.1 - 4.6e-05 23.7 0.3 0.00016 22.0 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Pkinase_fungal PF17667.1 GAN05862.1 - 0.00065 18.6 0.0 0.0014 17.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAN05862.1 - 0.001 18.4 0.4 0.002 17.5 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_EFTU_D4 PF14578.6 GAN05862.1 - 0.0015 18.3 0.4 0.0053 16.6 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FTA2 PF13095.6 GAN05862.1 - 0.0019 17.9 1.2 0.46 10.1 0.3 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAN05862.1 - 0.0035 17.3 0.2 0.012 15.6 0.1 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN05862.1 - 0.0081 15.1 0.5 0.0081 15.1 0.5 2.3 2 0 0 2 2 1 1 Haspin like kinase domain Ras PF00071.22 GAN05862.1 - 0.015 14.9 0.1 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 Ras family Roc PF08477.13 GAN05862.1 - 0.12 12.6 0.0 29 4.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynein_light PF01221.18 GAN05863.1 - 4.2e-42 142.4 1.1 4.6e-42 142.2 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Mem_trans PF03547.18 GAN05864.1 - 2.7e-25 88.6 1.3 3.5e-25 88.2 1.3 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF3464 PF11947.8 GAN05864.1 - 0.12 12.1 1.1 0.21 11.4 0.0 1.9 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 Pkinase PF00069.25 GAN05866.1 - 6.8e-41 140.4 0.0 2.4e-24 86.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05866.1 - 4.7e-18 65.4 0.0 1.1e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAN05866.1 - 0.0006 19.8 0.0 0.0067 16.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN05866.1 - 0.04 13.2 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 GAN05866.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sel1 PF08238.12 GAN05867.1 - 9.5e-33 111.9 53.0 0.00095 19.8 0.1 20.1 21 0 0 21 21 21 10 Sel1 repeat TPR_16 PF13432.6 GAN05867.1 - 1.1 10.0 0.0 1.1 10.0 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN05867.1 - 6.7 7.2 23.5 30 5.2 0.2 9.4 9 0 0 9 9 9 0 Tetratricopeptide repeat NDK PF00334.19 GAN05868.1 - 9.4e-13 48.3 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Beach PF02138.18 GAN05869.1 - 7.8e-40 137.0 0.0 1.5e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 GAN05869.1 - 1.9e-11 44.3 9.3 0.001 19.9 0.0 5.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05869.1 - 1.8e-09 37.7 0.2 0.0041 17.4 0.0 5.5 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 GAN05869.1 - 3.3e-08 33.2 0.0 2.7e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 GAN05869.1 - 0.0022 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WD40_like PF17005.5 GAN05869.1 - 0.0054 16.1 0.0 0.031 13.6 0.0 2.3 2 1 0 2 2 2 1 WD40-like domain Kdo PF06293.14 GAN05869.1 - 0.046 13.1 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAN05870.1 - 2.9e-51 174.4 0.0 4.3e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05870.1 - 3.5e-31 108.4 0.0 4.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05870.1 - 2.8e-06 26.9 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 GAN05870.1 - 0.0001 21.4 0.7 0.00015 20.8 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN05870.1 - 0.0012 18.3 0.2 0.0021 17.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN05870.1 - 0.087 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HLH PF00010.26 GAN05873.1 - 5.6e-10 39.0 1.1 1.8e-09 37.4 1.1 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Blo-t-5 PF11642.8 GAN05873.1 - 1.3 9.0 10.0 2.5 8.1 1.4 2.4 2 0 0 2 2 2 0 Mite allergen Blo t 5 VTC PF09359.10 GAN05874.1 - 4.2e-66 223.2 0.2 7.6e-66 222.3 0.2 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 GAN05874.1 - 1.7e-13 51.2 21.4 3.6e-06 27.2 0.1 4.5 3 1 1 5 5 5 4 SPX domain DUF202 PF02656.15 GAN05874.1 - 1.9e-11 44.2 0.7 3.6e-11 43.4 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Flagellin_N PF00669.20 GAN05874.1 - 0.03 14.4 0.2 0.03 14.4 0.2 1.9 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF3567 PF12091.8 GAN05874.1 - 0.12 12.5 0.4 0.32 11.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) End3 PF12761.7 GAN05874.1 - 2.4 8.3 7.0 11 6.1 0.3 3.2 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 GGA_N-GAT PF18308.1 GAN05875.1 - 0.018 14.7 0.5 0.057 13.1 0.5 1.9 1 0 0 1 1 1 0 GGA N-GAT domain Striatin PF08232.12 GAN05875.1 - 0.13 12.9 4.5 0.19 12.3 0.1 2.3 2 0 0 2 2 2 0 Striatin family ATG16 PF08614.11 GAN05875.1 - 1.4 9.1 8.1 2.6 8.2 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ribul_P_3_epim PF00834.19 GAN05878.1 - 1.6e-71 239.8 0.0 1.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 GAN05878.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 GAN05878.1 - 0.048 13.2 0.1 0.08 12.5 0.1 1.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family AMPK1_CBM PF16561.5 GAN05879.1 - 3.4e-34 116.9 0.2 7.2e-34 115.9 0.2 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 GAN05879.1 - 1.5e-20 73.2 1.8 1.5e-20 73.2 1.8 3.1 4 0 0 4 4 4 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 GAN05879.1 - 0.0036 17.9 0.1 0.012 16.1 0.1 1.9 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) GLTP PF08718.11 GAN05880.1 - 1.1e-39 136.1 0.1 1.6e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Mg_trans_NIPA PF05653.14 GAN05881.1 - 1.1e-24 87.1 15.6 7.4e-14 51.6 4.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAN05881.1 - 0.00017 21.7 7.5 0.00017 21.7 7.5 3.8 3 1 1 4 4 4 2 EamA-like transporter family CUE PF02845.16 GAN05882.1 - 2.2e-09 36.9 0.0 4.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 GAN05882.1 - 0.0037 17.3 0.1 0.0037 17.3 0.1 2.3 3 0 0 3 3 3 1 Ubiquitin-associated protein 2 SPRY PF00622.28 GAN05883.1 - 3.3e-10 40.1 2.7 1.1e-09 38.5 0.2 2.7 3 0 0 3 3 3 1 SPRY domain zf-C3HC4_3 PF13920.6 GAN05883.1 - 6.1e-10 38.8 2.9 1.1e-09 38.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN05883.1 - 0.00039 20.2 5.3 0.00082 19.2 5.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN05883.1 - 0.022 15.1 5.3 0.05 13.9 5.3 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 GAN05883.1 - 0.022 14.6 3.8 0.085 12.7 3.9 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Neprosin_AP PF14365.6 GAN05883.1 - 0.029 14.8 0.3 0.12 12.9 0.3 2.0 1 0 0 1 1 1 0 Neprosin activation peptide zf-RING_5 PF14634.6 GAN05883.1 - 0.98 9.4 4.4 2 8.5 4.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAN05883.1 - 1.4 8.8 5.3 3.8 7.4 5.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-LYAR PF08790.11 GAN05884.1 - 1.9e-14 53.2 5.7 4.3e-14 52.1 5.7 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 GAN05884.1 - 0.00071 19.1 0.2 0.7 9.5 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger AC_N PF16214.5 GAN05884.1 - 0.044 12.9 1.1 0.058 12.5 1.1 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TFIIE-A_C PF11521.8 GAN05884.1 - 0.3 11.4 4.4 0.14 12.5 1.9 1.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Arc_trans_TRASH PF08394.10 GAN05884.1 - 3.1 8.2 6.8 1.2 9.5 3.7 2.0 2 0 0 2 2 2 0 Archaeal TRASH domain BBS2_Mid PF14783.6 GAN05885.1 - 2.3e-08 34.0 0.1 0.0028 17.7 0.0 4.0 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 GAN05885.1 - 2.4e-07 31.3 0.2 0.002 18.7 0.0 3.6 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 GAN05885.1 - 5.8e-06 25.6 0.4 0.0018 17.4 0.1 3.3 3 1 1 4 4 4 1 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 GAN05885.1 - 0.02 15.0 0.1 0.02 15.0 0.1 2.9 3 0 0 3 3 3 0 FG-GAP repeat Trypan_PARP PF05887.11 GAN05886.1 - 8.4 6.4 29.9 14 5.6 10.0 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) EF-hand_7 PF13499.6 GAN05887.1 - 2.1e-25 89.0 5.9 1e-17 64.4 0.7 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAN05887.1 - 3.9e-22 76.1 14.4 5.3e-07 28.7 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAN05887.1 - 2.4e-21 73.8 11.4 3.6e-05 23.3 0.2 5.0 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 GAN05887.1 - 1.7e-17 62.1 10.0 3.2e-05 23.2 1.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAN05887.1 - 2.4e-14 52.9 13.2 1.4e-06 28.0 1.5 4.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 GAN05887.1 - 8.5e-08 32.1 7.5 0.15 12.0 0.3 3.8 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN05887.1 - 6.6e-05 23.2 1.9 0.071 13.4 0.3 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAN05887.1 - 0.0046 17.2 1.0 5.7 7.3 0.0 3.6 2 1 1 3 3 3 1 EF-hand domain DUF1707 PF08044.11 GAN05887.1 - 0.025 14.7 0.0 3.1 8.0 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) S10_plectin PF03501.15 GAN05887.1 - 0.047 13.8 0.0 0.081 13.0 0.0 1.5 1 1 0 1 1 1 0 Plectin/S10 domain EF-hand_14 PF17959.1 GAN05887.1 - 0.17 12.2 0.9 24 5.4 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Ras PF00071.22 GAN05888.1 - 1.5e-51 174.2 0.1 1.7e-51 174.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN05888.1 - 2.5e-16 60.0 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN05888.1 - 9e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN05888.1 - 0.0011 18.6 0.1 0.0046 16.5 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN05888.1 - 0.017 15.0 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NPR3 PF03666.13 GAN05889.1 - 7.3e-114 381.1 8.7 7.3e-114 381.1 8.7 2.6 2 1 1 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 GAN05889.1 - 0.0013 18.8 14.0 0.0013 18.8 14.0 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 GAN05889.1 - 0.063 12.9 0.1 0.063 12.9 0.1 4.3 4 0 0 4 4 4 0 FAM176 family SPX PF03105.19 GAN05889.1 - 0.95 9.3 32.7 0.36 10.7 10.4 3.0 3 0 0 3 3 3 0 SPX domain Glyco_tranf_2_3 PF13641.6 GAN05890.1 - 9e-20 71.5 0.4 1.4e-15 57.8 0.9 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 GAN05890.1 - 1.1e-12 47.4 10.1 5e-06 25.4 11.1 3.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN05890.1 - 1.2e-09 38.3 7.4 1.2e-09 38.3 7.4 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GAN05890.1 - 2.1e-05 24.1 0.5 5.7e-05 22.7 0.5 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAN05890.1 - 8.1e-05 22.5 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Tetraspanin PF00335.20 GAN05890.1 - 2.5 7.8 9.4 0.19 11.4 0.1 2.6 2 1 0 2 2 2 0 Tetraspanin family Methyltransf_25 PF13649.6 GAN05891.1 - 1.9e-16 60.5 0.0 6.3e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN05891.1 - 1.1e-15 57.7 0.0 5.8e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05891.1 - 1.1e-13 51.6 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05891.1 - 3e-13 49.9 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05891.1 - 3.3e-09 36.4 0.0 1.3e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN05891.1 - 2.3e-07 31.5 0.1 1.1e-06 29.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAN05891.1 - 8.3e-07 29.1 0.0 1.6e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 GAN05891.1 - 1.1e-05 24.2 0.0 3.5e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Activator_LAG-3 PF11498.8 GAN05891.1 - 0.036 13.1 0.7 0.052 12.5 0.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Methyltransf_4 PF02390.17 GAN05891.1 - 0.049 13.1 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase Mss4 PF04421.13 GAN05892.1 - 3.3e-24 84.8 0.0 4.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Mss4 protein Apolipoprotein PF01442.18 GAN05893.1 - 2.6e-05 24.2 21.0 2.6e-05 24.2 21.0 5.9 2 2 3 5 5 5 2 Apolipoprotein A1/A4/E domain DUF3135 PF11333.8 GAN05893.1 - 0.14 12.4 0.6 32 4.8 0.1 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF3135) TBPIP PF07106.13 GAN05893.1 - 0.17 11.8 1.5 5.2 7.1 0.1 4.0 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain DUF883 PF05957.13 GAN05893.1 - 0.48 11.1 61.6 0.18 12.4 4.2 8.6 5 2 3 8 8 8 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GAN05893.1 - 6.6 7.3 91.5 3.8 8.1 5.1 10.0 5 3 1 6 6 6 0 YtxH-like protein LIM_bind PF01803.16 GAN05894.1 - 3.1e-36 125.2 0.1 3.1e-36 125.2 0.1 5.7 3 3 1 4 4 4 1 LIM-domain binding protein TFIIA PF03153.13 GAN05894.1 - 0.0036 17.3 42.6 0.0036 17.3 42.6 3.2 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit UCR_14kD PF02271.16 GAN05895.1 - 0.34 10.9 5.9 0.71 9.9 0.1 3.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Cob_adeno_trans PF01923.18 GAN05895.1 - 2.9 8.0 15.4 17 5.5 0.1 4.4 3 1 0 3 3 3 0 Cobalamin adenosyltransferase Lipoprotein_21 PF14041.6 GAN05896.1 - 0.079 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 LppP/LprE lipoprotein DUF515 PF04415.12 GAN05896.1 - 0.3 9.4 6.5 0.33 9.3 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.16 GAN05897.1 - 1.3e-24 86.8 14.8 1.3e-24 86.8 14.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Haemagg_act PF05860.13 GAN05898.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 haemagglutination activity domain Methyltransf_31 PF13847.6 GAN05899.1 - 2e-18 66.6 0.0 5.8e-18 65.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN05899.1 - 2.1e-17 63.6 0.0 4.2e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05899.1 - 1.6e-15 57.5 0.0 2.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05899.1 - 1.1e-12 48.1 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN05899.1 - 1.4e-09 38.6 0.0 3.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05899.1 - 3.9e-08 32.9 0.0 6.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAN05899.1 - 4.1e-06 26.8 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 GAN05899.1 - 0.00038 19.1 0.0 0.0011 17.6 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 GAN05899.1 - 0.0023 17.4 0.0 0.07 12.6 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.18 GAN05899.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 GAN05900.1 - 1.3e-14 54.6 0.0 2.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN05900.1 - 4.3e-14 52.6 0.0 2.2e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN05900.1 - 3.6e-12 46.8 0.0 7.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN05900.1 - 1e-09 38.5 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05900.1 - 6.9e-08 32.1 0.0 3.2e-07 29.9 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAN05900.1 - 3.8e-07 30.2 0.0 7.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 GAN05900.1 - 4e-06 27.5 0.0 1.1e-05 26.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GAN05900.1 - 0.0046 15.6 0.0 0.0099 14.5 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1730 PF08331.10 GAN05900.1 - 0.079 12.9 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) PTPA PF03095.15 GAN05901.1 - 3.7e-92 309.0 0.0 5.3e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Arrestin_N PF00339.29 GAN05901.1 - 5.4e-06 26.5 0.1 1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 GAN05901.1 - 0.00011 21.6 0.4 0.00016 21.0 0.4 1.2 1 0 0 1 1 1 1 Rgp1 Acetyltransf_1 PF00583.25 GAN05902.1 - 7.3e-11 42.3 0.0 4.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN05902.1 - 1.9e-05 25.0 0.0 0.037 14.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN05902.1 - 0.005 16.8 0.0 0.32 11.0 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 GAN05902.1 - 0.031 14.4 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SH3_9 PF14604.6 GAN05903.1 - 1.8e-10 40.5 0.0 3.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 GAN05903.1 - 6.1e-10 39.2 0.3 6.1e-10 39.2 0.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 GAN05903.1 - 3.3e-08 33.0 0.1 3.3e-08 33.0 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 GAN05903.1 - 9.5e-05 22.0 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.25 GAN05905.1 - 4e-17 62.5 0.0 6.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I PF08311.12 GAN05905.1 - 4.7e-16 58.9 1.0 2.5e-15 56.5 0.2 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Choline_kinase PF01633.20 GAN05905.1 - 0.041 13.5 0.5 0.093 12.3 0.5 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 GAN05905.1 - 0.053 12.8 1.2 0.1 11.9 1.2 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 GAN05905.1 - 0.078 13.1 0.9 0.21 11.7 0.9 1.7 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Adap_comp_sub PF00928.21 GAN05906.1 - 9.8e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAN05906.1 - 1e-07 32.0 0.4 3.3e-06 27.1 0.1 2.2 2 0 0 2 2 2 1 Clathrin adaptor complex small chain ZZ PF00569.17 GAN05907.1 - 1.8e-07 30.8 3.7 2.9e-07 30.2 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 GAN05907.1 - 7.2e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN05907.1 - 0.0027 17.9 0.0 0.0069 16.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 GAN05907.1 - 0.013 15.8 3.9 0.027 14.8 3.9 1.5 1 0 0 1 1 1 0 C1 domain UPF0167 PF03691.14 GAN05907.1 - 0.018 14.8 1.1 0.036 13.8 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Zn_ribbon_2 PF12674.7 GAN05907.1 - 0.022 15.4 2.0 0.079 13.6 2.0 2.0 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-UBR PF02207.20 GAN05907.1 - 0.71 10.1 5.4 1.6 8.9 5.4 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 GAN05908.1 - 5.6e-53 180.0 0.0 8.4e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05908.1 - 1.5e-32 112.9 0.0 2.2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05908.1 - 2.3e-09 37.0 0.0 4.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN05908.1 - 0.007 16.3 0.0 1.1 9.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 GAN05908.1 - 0.026 14.2 0.8 0.68 9.5 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SPX PF03105.19 GAN05908.1 - 0.62 9.9 10.7 0.95 9.3 10.7 1.2 1 0 0 1 1 1 0 SPX domain Ribosomal_L6 PF00347.23 GAN05909.1 - 2.8e-28 98.4 7.2 5.9e-17 62.1 3.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 LIM PF00412.22 GAN05910.1 - 3.1e-24 84.9 69.3 3e-09 37.0 7.6 5.7 5 1 0 5 5 5 5 LIM domain RdRP PF05183.12 GAN05911.1 - 1.4e-130 436.7 0.0 2.3e-130 436.0 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3795 PF12675.7 GAN05911.1 - 0.021 15.3 0.2 0.067 13.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) RRM_1 PF00076.22 GAN05912.1 - 5e-20 71.1 0.2 8.5e-15 54.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_3 PF13302.7 GAN05913.1 - 6.7e-21 75.4 0.0 1e-20 74.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN05913.1 - 4.7e-08 33.3 0.0 7.4e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 GAN05913.1 - 0.0014 18.3 0.2 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN05913.1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.7 GAN05913.1 - 0.026 14.7 0.0 0.035 14.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box PF00646.33 GAN05914.1 - 0.0022 17.8 0.3 0.0063 16.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAN05914.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 F-box FAR1 PF03101.15 GAN05915.1 - 4.7e-06 27.2 0.3 1.3e-05 25.8 0.3 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain Gpr1_Fun34_YaaH PF01184.19 GAN05918.1 - 4.4e-73 245.3 16.6 5.3e-73 245.0 16.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.7 GAN05918.1 - 3.8 7.8 11.4 0.21 11.8 5.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) TPR_11 PF13414.6 GAN05919.1 - 1.3e-11 44.0 8.5 0.00096 18.8 0.0 5.6 6 0 0 6 6 6 3 TPR repeat TOM20_plant PF06552.12 GAN05919.1 - 6.5e-08 32.5 5.2 7.6e-06 25.8 2.1 2.9 2 1 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.6 GAN05919.1 - 1.6e-06 28.1 0.0 1.1 9.8 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN05919.1 - 6.7e-05 23.5 4.8 0.57 10.9 0.3 4.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN05919.1 - 0.0003 21.3 11.7 1.2 9.8 0.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN05919.1 - 0.0035 18.0 5.7 1.6 9.8 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAN05919.1 - 0.0095 15.7 11.0 6.7 6.7 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN05919.1 - 0.0095 16.0 14.9 4.7 7.6 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN05919.1 - 0.067 13.4 8.9 12 6.4 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAN05919.1 - 0.94 9.8 5.9 1.4 9.3 0.6 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF543 PF04418.12 GAN05920.1 - 1.3e-24 85.9 0.0 1.5e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) 2TM PF13239.6 GAN05920.1 - 0.031 14.6 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 2TM domain PGF-CTERM PF18204.1 GAN05920.1 - 2.2 8.3 4.5 6.2 6.9 0.2 2.3 2 0 0 2 2 2 0 PGF-CTERM motif HEAT PF02985.22 GAN05921.1 - 0.021 15.1 0.2 0.19 12.1 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat ubiquitin PF00240.23 GAN05923.1 - 6.5e-12 45.0 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 GAN05923.1 - 9.2e-10 38.2 0.1 9.2e-10 38.2 0.1 2.2 3 0 0 3 3 3 1 UBA/TS-N domain DUF2407 PF10302.9 GAN05923.1 - 0.00013 22.5 0.0 0.00097 19.7 0.0 2.5 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAN05923.1 - 0.00031 20.8 0.0 0.00083 19.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 GAN05923.1 - 0.0055 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 GAN05923.1 - 0.024 14.4 0.0 0.071 12.8 0.0 1.9 1 0 0 1 1 1 0 CUE domain STI1 PF17830.1 GAN05923.1 - 0.11 12.4 19.4 0.027 14.4 4.5 3.5 2 1 1 3 3 3 0 STI1 domain Ribosomal_L12_N PF16320.5 GAN05924.1 - 8.6 6.2 8.2 1 9.1 1.8 2.4 2 1 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain Mito_carr PF00153.27 GAN05925.1 - 6.5e-50 167.0 3.3 1.2e-22 79.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 GAN05926.1 - 3.9e-59 200.3 39.1 3.6e-43 147.8 14.1 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN05926.1 - 2.1e-11 43.3 19.7 1.1e-08 34.3 1.1 3.2 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 GAN05926.1 - 4e-11 42.4 6.6 3.5e-07 29.4 0.6 3.3 1 1 2 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 GAN05926.1 - 8.7e-10 37.7 9.0 2.5e-07 29.6 1.9 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 GAN05926.1 - 9.4e-09 35.0 8.7 0.00013 21.4 0.4 2.9 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 GAN05926.1 - 0.00044 18.7 5.4 0.034 12.4 0.7 3.0 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Transgly_assoc PF04226.13 GAN05926.1 - 6.7 7.1 8.7 10 6.5 0.2 3.6 3 0 0 3 3 3 0 Transglycosylase associated protein Ras PF00071.22 GAN05927.1 - 5.8e-47 159.3 2.1 4.4e-45 153.2 2.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAN05927.1 - 9.9e-31 106.5 0.3 1.5e-29 102.7 0.2 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN05927.1 - 5.9e-13 48.6 0.4 6.9e-08 32.1 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN05927.1 - 9.8e-07 28.3 0.3 5e-06 26.0 0.3 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN05927.1 - 5.6e-06 26.4 0.0 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN05927.1 - 7.5e-05 22.4 1.6 0.0043 16.6 0.3 2.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN05927.1 - 0.00033 20.6 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 GAN05927.1 - 0.046 13.0 0.1 0.081 12.2 0.0 1.6 2 0 0 2 2 2 0 AIG1 family SRPRB PF09439.10 GAN05927.1 - 0.046 13.1 0.1 0.088 12.2 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 GAN05927.1 - 0.087 13.1 0.1 0.36 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 GAN05927.1 - 0.14 11.7 0.1 5.7 6.4 0.1 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B Pex14_N PF04695.13 GAN05928.1 - 4.5e-33 115.1 0.8 4.5e-33 115.1 0.8 3.1 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TBCA PF02970.16 GAN05928.1 - 0.036 14.4 1.2 0.066 13.5 1.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A Y_phosphatase2 PF03162.13 GAN05928.1 - 0.058 13.0 0.0 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF3439 PF11921.8 GAN05928.1 - 1.4 8.9 6.9 0.079 12.9 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FadA PF09403.10 GAN05928.1 - 1.8 9.1 6.6 1 9.9 3.3 2.2 2 1 0 2 2 2 0 Adhesion protein FadA tRNA_bind PF01588.20 GAN05929.1 - 4.5e-26 90.8 0.0 7.1e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain PBP PF01161.20 GAN05930.1 - 4.6e-15 56.1 0.1 9.6e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Asp_Glu_race_2 PF14669.6 GAN05930.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative aspartate racemase PDZ_5 PF17817.1 GAN05931.1 - 0.00014 22.0 0.1 0.0012 19.1 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Herpes_US9 PF06072.11 GAN05933.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ATP-synt_ab PF00006.25 GAN05934.1 - 3.6e-27 95.4 0.0 5.3e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAN05934.1 - 1.6e-20 73.4 0.6 4.7e-20 71.9 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 GAN05934.1 - 0.07 13.3 0.2 0.26 11.4 0.1 2.0 2 1 0 2 2 2 0 HAS barrel domain Pro_dh PF01619.18 GAN05934.1 - 0.098 12.2 0.1 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Proline dehydrogenase RbcS PF12338.8 GAN05934.1 - 1.9 8.7 4.5 7.8 6.8 0.6 3.4 4 0 0 4 4 4 0 Ribulose-1,5-bisphosphate carboxylase small subunit PX PF00787.24 GAN05935.1 - 7.6e-22 77.4 0.5 1.6e-21 76.4 0.5 1.5 1 0 0 1 1 1 1 PX domain tRNA_U5-meth_tr PF05958.11 GAN05936.1 - 4.6e-14 52.2 3.5 1.4e-13 50.6 0.8 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAN05936.1 - 6.9e-09 35.7 0.1 2.1e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN05936.1 - 4.5e-07 29.6 0.1 1e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 GAN05936.1 - 1.1e-06 28.3 0.6 1.2e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 GAN05936.1 - 2e-06 27.6 0.0 4.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 GAN05936.1 - 4.6e-06 27.2 0.0 1.9e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAN05936.1 - 7.5e-05 22.3 0.5 7.5e-05 22.3 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 GAN05936.1 - 0.0026 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 GAN05936.1 - 0.0079 15.7 0.4 0.02 14.4 0.4 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 GAN05936.1 - 0.021 14.8 1.5 0.066 13.2 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.18 GAN05936.1 - 0.025 13.9 0.1 0.058 12.7 0.1 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 GAN05936.1 - 0.058 13.0 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) AviRa PF11599.8 GAN05936.1 - 0.061 12.8 0.7 0.18 11.2 0.0 2.2 3 0 0 3 3 3 0 RRNA methyltransferase AviRa TPMT PF05724.11 GAN05936.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 GAN05936.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 GAN05936.1 - 0.1 12.3 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 GAN05936.1 - 0.11 13.2 0.0 0.44 11.2 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain zf-H2C2_2 PF13465.6 GAN05937.1 - 9.5e-17 60.6 12.7 3.7e-09 36.6 0.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAN05937.1 - 1.3e-13 50.6 18.7 3.4e-05 24.1 0.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN05937.1 - 1.5e-12 47.2 15.5 0.00012 22.6 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN05937.1 - 5.8e-08 32.5 13.3 2.4e-05 24.2 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-LYAR PF08790.11 GAN05937.1 - 3.9e-05 23.5 6.8 0.019 14.9 0.1 3.2 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 GAN05937.1 - 5.8e-05 23.3 9.1 0.48 10.8 0.0 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 GAN05937.1 - 0.00034 20.7 5.6 0.014 15.5 2.4 2.7 2 1 0 2 2 2 1 Zinc ribbon domain Lebercilin PF15619.6 GAN05937.1 - 0.0025 17.5 0.2 0.0025 17.5 0.2 1.6 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease zf-C2HE PF16278.5 GAN05937.1 - 0.0042 17.5 16.3 0.71 10.4 0.8 4.1 2 1 2 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 GAN05937.1 - 0.0068 16.1 8.9 0.66 9.8 0.2 3.6 3 0 0 3 3 3 1 zinc-finger C2H2-type SIKE PF05769.11 GAN05937.1 - 0.024 14.6 0.4 0.043 13.8 0.4 1.3 1 0 0 1 1 1 0 SIKE family C1_4 PF07975.12 GAN05937.1 - 0.045 14.0 10.3 1.1 9.6 9.1 2.9 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 GAN05937.1 - 0.056 14.1 6.0 3.2 8.4 6.0 3.1 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 GAN05937.1 - 0.061 13.2 0.3 0.061 13.2 0.3 2.0 2 0 0 2 2 1 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 GAN05937.1 - 0.072 12.9 0.1 0.072 12.9 0.1 2.2 3 0 0 3 3 2 0 Rad50 zinc hook motif zf-met PF12874.7 GAN05937.1 - 0.073 13.5 8.5 0.15 12.5 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 GAN05937.1 - 0.085 12.5 6.1 8.2 6.1 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 GAN05937.1 - 0.1 12.5 6.8 2.3 8.1 0.2 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) BolA PF01722.18 GAN05937.1 - 0.11 12.8 1.3 2 8.8 0.9 2.7 2 1 1 3 3 2 0 BolA-like protein TSC22 PF01166.18 GAN05937.1 - 0.14 12.5 0.6 0.31 11.4 0.6 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family zf_ZIC PF18366.1 GAN05937.1 - 0.14 12.3 2.4 5.9 7.1 0.2 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 GAN05937.1 - 0.28 11.5 11.8 3.7 7.9 0.2 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc-ribbons_6 PF07191.12 GAN05937.1 - 0.38 10.8 7.4 93 3.1 7.4 3.1 1 1 0 1 1 1 0 zinc-ribbons zf-trcl PF13451.6 GAN05937.1 - 0.4 10.6 4.4 6.6 6.7 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 GAN05937.1 - 0.51 10.3 13.6 1.9 8.5 0.7 3.1 2 1 1 3 3 3 0 SprT-like zinc ribbon domain DUF2256 PF10013.9 GAN05937.1 - 0.52 10.5 3.3 4.6 7.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DZR PF12773.7 GAN05937.1 - 0.63 10.1 9.1 19 5.4 9.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf_C2H2_ZHX PF18387.1 GAN05937.1 - 0.67 9.6 10.1 2.3 7.9 1.6 3.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain XPA_N PF01286.18 GAN05937.1 - 1.8 8.7 6.2 11 6.1 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal PHD PF00628.29 GAN05937.1 - 2.1 8.3 7.3 35 4.4 4.1 2.9 2 1 0 2 2 2 0 PHD-finger zf-AN1 PF01428.16 GAN05937.1 - 2.5 8.4 14.4 11 6.3 0.5 3.5 1 1 2 3 3 3 0 AN1-like Zinc finger zinc_ribbon_15 PF17032.5 GAN05937.1 - 2.7 8.8 7.1 13 6.6 6.6 2.1 1 1 1 2 2 2 0 zinc-ribbon family LON_substr_bdg PF02190.16 GAN05938.1 - 1.8e-19 70.5 0.1 4.9e-17 62.5 0.1 2.3 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 GAN05938.1 - 3.3e-11 42.8 13.8 7.2e-11 41.7 13.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN05938.1 - 1.1e-08 35.2 14.9 1.1e-08 35.2 14.9 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAN05938.1 - 1.9e-08 34.0 14.0 3.6e-08 33.1 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN05938.1 - 3.3e-08 33.3 13.9 6.8e-08 32.3 13.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN05938.1 - 1.2e-07 31.6 12.7 1.2e-07 31.6 12.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAN05938.1 - 4.7e-07 29.6 13.5 2.4e-06 27.3 13.8 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAN05938.1 - 1e-06 28.6 13.9 2.2e-06 27.5 13.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAN05938.1 - 3e-05 24.1 10.9 9e-05 22.6 10.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAN05938.1 - 0.0043 17.3 10.6 0.083 13.2 11.3 2.6 1 1 1 2 2 2 1 RING-H2 zinc finger domain TFIIA PF03153.13 GAN05938.1 - 0.093 12.7 32.9 0.13 12.2 32.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_4 PF14570.6 GAN05938.1 - 0.14 12.0 10.7 0.31 10.9 10.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 GAN05938.1 - 0.16 12.1 8.5 0.37 11.0 8.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 GAN05938.1 - 0.37 10.7 9.2 1.3 8.9 9.2 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PAT1 PF09770.9 GAN05938.1 - 1.3 7.2 24.0 2.2 6.5 24.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TerY_C PF15616.6 GAN05938.1 - 2.8 8.1 11.4 0.087 12.9 5.0 1.7 2 0 0 2 2 1 0 TerY-C metal binding domain zinc-ribbons_6 PF07191.12 GAN05938.1 - 5.1 7.2 9.9 11 6.1 9.9 1.5 1 0 0 1 1 1 0 zinc-ribbons Ndc1_Nup PF09531.10 GAN05938.1 - 7.1 5.2 13.8 10 4.6 13.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup O-FucT PF10250.9 GAN05939.1 - 9.1e-20 71.6 0.4 6.8e-11 42.5 0.1 3.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase FYRN PF05964.14 GAN05940.1 - 2.8e-19 68.7 0.1 5e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 GAN05940.1 - 1.3e-17 63.7 0.0 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus Peptidase_M36 PF02128.15 GAN05941.1 - 1.5e-150 501.5 4.6 2e-150 501.1 4.6 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 GAN05941.1 - 8.8e-18 63.9 1.6 2.8e-17 62.3 1.6 2.0 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 GAN05941.1 - 0.00061 19.7 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Whi5 PF08528.11 GAN05942.1 - 3.6e-08 32.8 0.0 3.6e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Whi5 like DUF4718 PF15842.5 GAN05942.1 - 0.42 10.4 5.2 0.7 9.7 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Pmp3 PF01679.17 GAN05943.1 - 1.3e-19 70.2 8.8 1.5e-19 69.9 8.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pterin_bind PF00809.22 GAN05944.1 - 5.5e-82 275.1 0.5 9e-82 274.4 0.5 1.4 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 GAN05944.1 - 6.4e-48 161.9 2.7 1.7e-23 83.3 0.1 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 GAN05944.1 - 3.4e-36 124.2 0.0 2.1e-35 121.6 0.0 2.1 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) UQ_con PF00179.26 GAN05945.1 - 9.2e-17 61.0 0.0 1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN05945.1 - 0.017 15.4 0.1 0.022 15.0 0.1 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_A PF14457.6 GAN05945.1 - 0.099 12.3 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A AA_permease PF00324.21 GAN05946.1 - 1.1e-124 416.7 39.6 1.3e-124 416.5 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN05946.1 - 1.3e-43 149.5 43.6 1.6e-43 149.2 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.20 GAN05947.1 - 1.8e-50 170.9 0.5 2.7e-49 167.1 0.2 3.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAN05947.1 - 8.9e-15 55.5 0.2 2.5e-14 54.1 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN05947.1 - 1.3e-14 53.6 0.0 3.4e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN05947.1 - 1.5e-05 24.8 0.3 3.2e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN05947.1 - 0.00091 19.3 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) NARG2_C PF10505.9 GAN05948.1 - 4.8e-18 65.5 0.0 8.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus CLPTM1 PF05602.12 GAN05949.1 - 1e-56 192.8 17.4 4.4e-49 167.7 3.2 2.8 2 1 1 3 3 3 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) U-box PF04564.15 GAN05949.1 - 8e-06 25.9 0.1 3.1e-05 24.1 0.1 2.1 1 0 0 1 1 1 1 U-box domain zf-CCHC_2 PF13696.6 GAN05949.1 - 0.00026 20.8 7.1 0.00026 20.8 7.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 GAN05949.1 - 0.00036 20.5 1.4 0.00085 19.3 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GAN05949.1 - 0.00042 20.2 0.4 0.0011 18.8 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.6 GAN05949.1 - 0.0021 18.4 8.6 0.0021 18.4 8.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN05949.1 - 0.12 12.2 10.2 0.32 10.9 10.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN05949.1 - 0.15 11.9 10.9 0.023 14.5 6.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4112 PF13430.6 GAN05949.1 - 0.18 12.1 0.6 0.51 10.6 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) PQ-loop PF04193.14 GAN05949.1 - 0.18 11.6 0.7 0.38 10.6 0.7 1.5 1 0 0 1 1 1 0 PQ loop repeat zf-C2HC5 PF06221.13 GAN05949.1 - 0.57 10.2 6.0 1.4 9.0 6.0 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Prok-RING_4 PF14447.6 GAN05949.1 - 4 7.4 7.7 12 5.8 7.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA PF00004.29 GAN05950.1 - 8.5e-43 145.9 0.0 1.5e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAN05950.1 - 2.1e-27 94.9 0.2 1.2e-26 92.5 0.0 2.4 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 GAN05950.1 - 3.1e-18 65.6 6.1 2.2e-16 59.7 6.1 2.5 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 GAN05950.1 - 5.8e-09 35.6 0.0 1.9e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAN05950.1 - 8.5e-06 26.2 0.1 0.0001 22.8 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAN05950.1 - 2.5e-05 24.3 0.0 0.00011 22.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAN05950.1 - 3e-05 23.8 0.0 7.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAN05950.1 - 6.2e-05 23.3 0.1 0.015 15.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAN05950.1 - 0.00016 21.5 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 GAN05950.1 - 0.00032 20.0 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 GAN05950.1 - 0.00042 20.3 0.0 0.0016 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN05950.1 - 0.00047 20.5 0.1 0.016 15.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase DUF815 PF05673.13 GAN05950.1 - 0.0005 19.3 0.0 0.002 17.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAN05950.1 - 0.0018 18.8 0.0 0.0052 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAN05950.1 - 0.0023 18.0 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAN05950.1 - 0.0026 18.0 0.0 0.0066 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAN05950.1 - 0.0026 17.3 0.1 0.16 11.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF3543 PF12063.8 GAN05950.1 - 0.0043 16.5 0.2 0.007 15.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) AAA_24 PF13479.6 GAN05950.1 - 0.01 15.6 0.0 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAN05950.1 - 0.012 16.1 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAN05950.1 - 0.022 14.1 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 GAN05950.1 - 0.03 13.7 0.0 2.8 7.2 0.0 2.5 1 1 0 2 2 2 0 KaiC Torsin PF06309.11 GAN05950.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Torsin TPR_1 PF00515.28 GAN05950.1 - 0.057 13.3 1.2 0.2 11.5 1.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_7 PF12775.7 GAN05950.1 - 0.061 12.8 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 GAN05950.1 - 0.074 13.0 0.0 0.89 9.4 0.0 2.2 1 1 1 2 2 2 0 NACHT domain TPR_2 PF07719.17 GAN05950.1 - 0.31 11.3 4.7 0.13 12.4 0.9 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Atg29_N PF18388.1 GAN05952.1 - 3.5e-18 65.2 0.2 6.6e-18 64.3 0.2 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain Myb_DNA-bind_6 PF13921.6 GAN05952.1 - 0.0032 17.7 0.3 0.01 16.1 0.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M24 PF00557.24 GAN05953.1 - 5.1e-22 78.6 0.4 7.8e-22 78.0 0.3 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.31 GAN05954.1 - 8e-07 29.1 0.1 1.7e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 GAN05954.1 - 0.0058 16.6 0.0 0.0058 16.6 0.0 1.2 1 1 0 1 1 1 1 Pam16 DUF5353 PF17304.2 GAN05954.1 - 0.049 13.4 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Pkinase PF00069.25 GAN05955.1 - 2.3e-77 259.9 0.0 3.1e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05955.1 - 8.9e-43 146.4 0.0 1.2e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN05955.1 - 2.2e-10 40.4 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN05955.1 - 2.9e-06 26.5 0.2 5.4e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAN05955.1 - 0.00027 20.9 0.2 0.00064 19.7 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN05955.1 - 0.0029 17.0 0.5 0.0048 16.3 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ntox14 PF15522.6 GAN05955.1 - 0.043 13.2 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Novel toxin 14 BAG6 PF12057.8 GAN05956.1 - 0.042 13.5 4.2 4.9 6.9 0.2 3.3 1 1 2 3 3 3 0 BCL2-associated athanogene 6 Pro_isomerase PF00160.21 GAN05957.1 - 1.8e-49 168.1 0.4 4e-49 166.9 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAN05957.1 - 5.7e-08 33.3 0.2 0.014 16.3 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN05957.1 - 0.0011 19.2 0.0 0.37 11.1 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN05957.1 - 0.098 11.3 1.2 1.6 7.3 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_L13 PF00572.18 GAN05958.1 - 8.7e-53 177.8 0.3 1e-52 177.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 OHCU_decarbox PF09349.10 GAN05959.1 - 1.9e-43 148.6 0.1 2.2e-43 148.4 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase TPR_1 PF00515.28 GAN05960.1 - 3.7e-61 200.6 23.2 3.2e-08 33.1 0.1 10.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAN05960.1 - 5e-54 176.1 24.1 5e-06 26.2 0.1 9.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAN05960.1 - 6.6e-41 135.1 25.8 2.9e-07 30.2 0.0 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 GAN05960.1 - 2.2e-31 106.0 15.2 0.00039 20.6 0.1 10.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 GAN05960.1 - 3.1e-31 105.4 13.6 0.00088 19.9 0.1 9.1 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 GAN05960.1 - 5.2e-28 97.4 11.5 9.8e-07 29.3 0.9 6.7 5 2 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAN05960.1 - 2.3e-27 95.1 25.4 4.1e-07 30.2 0.1 7.8 6 2 1 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAN05960.1 - 3.1e-26 91.7 16.9 6.4e-05 23.4 0.6 6.7 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAN05960.1 - 3.3e-24 83.1 16.4 0.00043 20.1 0.1 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 GAN05960.1 - 4.4e-23 80.3 17.2 0.023 15.3 1.5 8.9 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 GAN05960.1 - 2.4e-22 78.3 34.5 4.3e-06 26.3 0.4 8.7 4 2 5 9 9 9 6 TPR repeat TPR_9 PF13371.6 GAN05960.1 - 2.3e-19 69.3 11.0 0.00089 19.4 0.2 6.8 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_15 PF13429.6 GAN05960.1 - 5.5e-11 42.2 13.7 0.1 11.8 0.1 6.1 1 1 5 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN05960.1 - 9.5e-10 38.6 17.2 1.5e-05 25.1 2.8 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAN05960.1 - 1.5e-06 27.9 18.4 0.11 12.4 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAN05960.1 - 6e-06 26.1 9.6 0.0048 16.6 0.3 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 GAN05960.1 - 8.5e-06 25.4 15.2 0.005 16.3 1.1 4.8 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 GAN05960.1 - 0.00016 21.2 7.4 0.1 12.0 0.1 4.0 3 1 1 4 4 4 2 MalT-like TPR region DUF2225 PF09986.9 GAN05960.1 - 0.0016 18.2 9.8 0.16 11.7 0.6 3.6 2 2 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) DUF4919 PF16266.5 GAN05960.1 - 0.0018 18.3 0.2 0.1 12.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) ChAPs PF09295.10 GAN05960.1 - 0.0042 16.1 3.1 0.71 8.8 0.2 3.1 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF627 PF04781.12 GAN05960.1 - 0.0076 16.2 2.6 1.3 9.0 0.5 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF627) TPR_20 PF14561.6 GAN05960.1 - 0.0083 16.4 7.1 7.9 6.9 0.0 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 GAN05960.1 - 0.014 15.5 28.4 6.2 7.0 2.2 7.4 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 GAN05960.1 - 0.025 15.0 9.3 1 9.8 0.8 3.7 2 2 1 4 4 4 0 Bacterial transcriptional activator domain DUF5344 PF17279.2 GAN05960.1 - 0.043 14.4 7.5 20 5.8 0.1 5.3 5 0 0 5 5 5 0 Family of unknown function (DUF5344) Tcf25 PF04910.14 GAN05960.1 - 0.047 12.8 5.4 0.43 9.6 0.0 3.0 2 2 1 3 3 3 0 Transcriptional repressor TCF25 DUF2989 PF11207.8 GAN05960.1 - 0.18 11.5 9.0 0.79 9.4 1.2 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2989) DUF5492 PF17596.2 GAN05960.1 - 0.44 10.9 1.7 1.2 9.5 0.1 2.4 3 0 0 3 3 2 0 Family of unknown function (DUF5492) TPR_3 PF07720.12 GAN05960.1 - 2.7 8.1 23.3 7.6 6.6 1.1 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 GAN05961.1 - 1.9e-41 142.3 0.1 4.1e-41 141.2 0.1 1.5 1 0 0 1 1 1 1 Subtilase family DnaJ_C PF01556.18 GAN05961.1 - 8e-38 129.8 0.0 1.5e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN05961.1 - 2e-25 88.7 4.1 2e-25 88.7 4.1 1.9 2 0 0 2 2 2 1 DnaJ domain P_proprotein PF01483.20 GAN05961.1 - 1.3e-23 82.8 0.6 3.1e-23 81.6 0.6 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain DnaJ_CXXCXGXG PF00684.19 GAN05961.1 - 1.6e-07 31.6 21.9 4.2e-07 30.2 21.9 1.8 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 GAN05961.1 - 0.00087 19.2 0.2 0.00087 19.2 0.2 2.7 4 0 0 4 4 4 1 Cytochrome c7 and related cytochrome c S8_pro-domain PF16470.5 GAN05961.1 - 0.0009 20.0 0.2 0.0027 18.4 0.2 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 GAN05961.1 - 0.057 13.9 0.3 0.16 12.5 0.3 1.7 1 0 0 1 1 1 0 N-terminal of Subtilase family zf-C3HC4_3 PF13920.6 GAN05961.1 - 0.49 10.3 4.2 1 9.3 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ING PF12998.7 GAN05962.1 - 6e-16 58.9 3.4 1.9e-15 57.2 3.4 1.8 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAN05962.1 - 8.5e-06 25.6 8.1 1.7e-05 24.6 8.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAN05962.1 - 0.019 14.5 2.7 0.044 13.4 2.7 1.7 1 0 0 1 1 1 0 PHD-finger Ecl1 PF12855.7 GAN05962.1 - 0.025 15.7 3.8 0.04 15.1 3.8 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins LolA PF03548.15 GAN05962.1 - 0.029 14.1 0.2 0.049 13.3 0.2 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA MscS_porin PF12795.7 GAN05962.1 - 0.044 13.3 0.2 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain zf-HC5HC2H PF13771.6 GAN05962.1 - 0.046 14.0 0.7 0.046 14.0 0.7 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain FlaC_arch PF05377.11 GAN05962.1 - 0.087 13.2 0.9 11 6.5 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 GAN05963.1 - 8.1e-66 222.1 0.0 1e-65 221.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN05963.1 - 3.2e-40 138.1 0.0 4.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN05963.1 - 1.7e-06 27.1 0.1 7.2e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN05963.1 - 0.00046 19.6 0.0 0.001 18.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN05963.1 - 0.0066 15.8 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAN05963.1 - 0.0088 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 GAN05963.1 - 0.012 14.6 0.1 0.057 12.4 0.1 1.9 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 GAN05963.1 - 0.18 11.7 0.0 2.6 7.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L37e PF01907.19 GAN05964.1 - 2.3e-27 94.9 12.0 4e-27 94.1 12.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 GAN05964.1 - 0.0086 16.1 1.8 0.014 15.4 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 GAN05964.1 - 0.018 15.0 1.0 0.027 14.5 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SelR PF01641.18 GAN05964.1 - 0.039 14.0 1.5 0.048 13.7 1.5 1.4 1 1 0 1 1 1 0 SelR domain zf-RING_5 PF14634.6 GAN05964.1 - 0.055 13.4 4.5 0.085 12.8 4.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.6 GAN05964.1 - 0.26 11.0 3.9 7.3 6.5 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 GAN05964.1 - 0.3 10.8 4.4 1.2 8.9 0.9 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S14 PF00253.21 GAN05964.1 - 0.36 10.6 6.4 0.49 10.2 0.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-C3HC4_2 PF13923.6 GAN05964.1 - 0.83 9.5 5.3 1.4 8.8 5.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3699 PF12480.8 GAN05965.1 - 0.39 10.9 2.0 16 5.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3699) Formyl_trans_N PF00551.19 GAN05966.1 - 5.8e-28 97.9 0.0 1e-27 97.0 0.0 1.4 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 GAN05966.1 - 1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Acetyltransf_1 PF00583.25 GAN05967.1 - 8.6e-16 58.2 0.1 1.1e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN05967.1 - 1.3e-07 32.0 0.0 1.9e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN05967.1 - 1.3e-05 25.1 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN05967.1 - 5.9e-05 23.0 0.0 0.00013 21.8 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 GAN05967.1 - 0.02 15.6 0.0 0.03 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAN05967.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LOH1CR12 PF10158.9 GAN05968.1 - 0.012 15.6 0.5 0.024 14.7 0.5 1.4 1 0 0 1 1 1 0 Tumour suppressor protein CmlA_N PF18456.1 GAN05968.1 - 0.23 10.8 3.1 0.44 9.8 0.2 2.1 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain DBR1 PF05011.13 GAN05969.1 - 6.7e-37 127.0 0.2 1.1e-36 126.3 0.2 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.7 GAN05969.1 - 0.0015 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ras PF00071.22 GAN05970.1 - 2.1e-58 196.5 0.4 2.7e-58 196.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN05970.1 - 2.4e-37 127.8 0.1 4.1e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN05970.1 - 1.1e-15 57.5 0.1 1.4e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAN05970.1 - 9.7e-06 25.1 0.1 1.2e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAN05970.1 - 1.4e-05 24.7 0.1 0.0001 21.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN05970.1 - 1.6e-05 24.9 0.1 3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN05970.1 - 2.2e-05 24.4 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAN05970.1 - 2.7e-05 23.7 0.2 3.4e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAN05970.1 - 0.0029 17.2 0.2 0.11 12.0 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 GAN05970.1 - 0.019 14.8 0.1 0.08 12.7 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 GAN05970.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sec63 PF02889.16 GAN05971.1 - 4.3e-175 579.9 0.4 3.2e-95 318.1 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAN05971.1 - 9.5e-50 168.8 0.2 9.3e-27 93.9 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GAN05971.1 - 2.5e-35 121.0 0.1 9.8e-35 119.1 0.1 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 GAN05971.1 - 3.1e-27 95.6 0.5 2.4e-14 53.7 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN05971.1 - 6.9e-15 55.3 0.0 1.4e-07 31.8 0.0 4.1 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAN05971.1 - 1.1e-07 31.8 0.0 0.029 14.1 0.0 4.0 3 1 0 4 4 4 2 AAA domain AAA_22 PF13401.6 GAN05971.1 - 7.3e-07 29.5 0.1 0.039 14.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 GAN05971.1 - 0.00061 20.0 0.0 1.9 8.7 0.0 3.9 4 1 0 4 4 4 1 Helicase C-terminal domain PhoH PF02562.16 GAN05971.1 - 0.0033 16.9 0.0 0.14 11.6 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA PF00004.29 GAN05971.1 - 0.012 16.1 0.3 0.3 11.5 0.2 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3774 PF12609.8 GAN05972.1 - 2.4 9.2 7.5 6.1 7.9 7.5 1.7 1 0 0 1 1 1 0 Wound-induced protein Peptidase_M73 PF12389.8 GAN05972.1 - 3 7.6 9.6 0.046 13.6 0.8 2.1 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase Presenilin PF01080.17 GAN05972.1 - 6.3 5.5 7.8 11 4.6 7.8 1.3 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 GAN05972.1 - 7.9 5.2 12.2 13 4.4 12.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Bromo_coat PF01318.18 GAN05981.1 - 0.048 13.7 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Bromovirus coat protein IIGP PF05049.13 GAN05982.1 - 1.5e-26 93.4 0.0 2.9e-26 92.4 0.0 1.4 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 GAN05982.1 - 1.4e-10 41.2 0.0 3.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 GAN05982.1 - 1.5e-05 25.2 0.0 0.00083 19.6 0.0 2.7 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAN05982.1 - 0.00019 21.6 0.0 0.12 12.4 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 GAN05982.1 - 0.00024 20.7 0.4 0.12 11.9 0.1 2.5 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN05982.1 - 0.00059 19.8 0.1 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 GAN05982.1 - 0.00061 20.1 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 GAN05982.1 - 0.00069 19.2 0.0 0.0047 16.5 0.0 2.4 2 2 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 GAN05982.1 - 0.0018 17.9 0.3 0.014 15.0 0.0 2.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 GAN05982.1 - 0.0043 17.3 0.0 0.0095 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAN05982.1 - 0.0053 17.3 0.0 0.029 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAN05982.1 - 0.0056 15.8 0.2 0.017 14.2 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 GAN05982.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 GAN05982.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAN05982.1 - 0.057 13.8 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 GAN05982.1 - 0.1 11.6 0.3 0.28 10.1 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 GAN05982.1 - 0.12 11.7 0.4 7.1 5.9 0.1 2.2 2 0 0 2 2 2 0 KaiC PPR_2 PF13041.6 GAN05983.1 - 4.9e-55 183.5 24.7 1.6e-10 41.0 0.3 11.2 8 2 4 12 12 12 9 PPR repeat family PPR PF01535.20 GAN05983.1 - 3.7e-28 95.8 24.2 1.7e-06 27.9 0.1 11.9 13 0 0 13 13 13 6 PPR repeat PPR_3 PF13812.6 GAN05983.1 - 7e-28 96.5 10.8 3.7e-10 39.7 0.1 8.6 7 2 2 9 9 9 6 Pentatricopeptide repeat domain PPR_long PF17177.4 GAN05983.1 - 1.3e-23 83.5 0.4 6.9e-13 48.5 0.0 3.9 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAN05983.1 - 2.7e-22 78.1 11.0 4.9e-07 29.3 0.0 8.7 8 0 0 8 8 8 5 PPR repeat RPM2 PF08579.11 GAN05983.1 - 0.00043 20.7 4.2 0.35 11.3 0.2 4.8 3 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 GAN05983.1 - 0.00084 19.2 1.2 0.5 10.2 0.0 3.8 4 0 0 4 4 4 1 Mitochondrial ATPase expression MRP-S27 PF10037.9 GAN05983.1 - 0.0047 15.8 0.2 0.66 8.8 0.0 3.0 3 0 0 3 3 3 1 Mitochondrial 28S ribosomal protein S27 AEP1 PF17049.5 GAN05983.1 - 0.033 13.3 0.7 3 6.8 0.4 2.7 2 1 0 2 2 2 0 ATPase expression protein 1 TRAF_BIRC3_bd PF16673.5 GAN05983.1 - 0.94 9.3 5.1 0.24 11.2 1.3 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain HEAT PF02985.22 GAN05984.1 - 0.00043 20.3 0.0 0.13 12.5 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat UVR PF02151.19 GAN05984.1 - 0.0013 18.4 1.2 0.0033 17.1 1.2 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif TRAF6_Z2 PF18048.1 GAN05984.1 - 0.041 14.0 0.4 0.041 14.0 0.4 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 HEAT_2 PF13646.6 GAN05984.1 - 0.07 13.5 0.1 0.82 10.1 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats Ndc1_Nup PF09531.10 GAN05984.1 - 0.22 10.2 12.3 0.078 11.7 6.2 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup zf_UBZ PF18439.1 GAN05984.1 - 1.2 8.8 6.6 0.2 11.3 0.3 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger LNS2 PF08235.13 GAN05987.1 - 0.084 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) RSN1_7TM PF02714.15 GAN05988.1 - 1.8e-55 188.2 32.1 3.8e-31 108.4 9.0 2.4 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAN05988.1 - 1e-39 136.6 0.0 2.1e-39 135.5 0.0 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAN05988.1 - 1.5e-31 109.3 1.5 1.5e-31 109.3 1.5 3.3 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport p450 PF00067.22 GAN05989.1 - 8.3e-77 258.9 0.0 1e-76 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAM2 PF07145.15 GAN05989.1 - 0.15 11.8 0.1 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region UPF0139 PF03669.13 GAN05990.1 - 1.6e-10 40.7 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF4646 PF15496.6 GAN05990.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Paf1 PF03985.13 GAN05991.1 - 1.6e-47 162.5 2.0 1.8e-47 162.4 2.0 1.0 1 0 0 1 1 1 1 Paf1 Methyltr_RsmB-F PF01189.17 GAN05991.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F ACOX PF01756.19 GAN05992.1 - 2.6e-50 170.5 0.8 3.5e-50 170.0 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAN05992.1 - 1.1e-29 103.5 0.4 2.4e-29 102.4 0.4 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAN05992.1 - 1.6e-13 50.7 0.0 3.4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAN05992.1 - 0.00017 21.8 0.4 0.0007 19.8 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAN05992.1 - 0.00071 20.2 0.0 0.0025 18.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Chitin_synth_2 PF03142.15 GAN05994.1 - 5.9e-238 790.8 1.5 9.1e-238 790.1 1.5 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAN05994.1 - 1.5e-120 403.5 6.6 2e-120 403.1 6.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 GAN05994.1 - 2.9e-16 59.4 0.5 6.3e-14 51.9 0.1 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 GAN05994.1 - 9.2e-14 51.9 0.0 1.9e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN05994.1 - 2.1e-11 44.1 1.4 2.1e-11 44.1 1.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAN05994.1 - 3.8e-06 26.8 0.0 0.0034 17.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN05994.1 - 0.0016 17.9 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.6 GAN05994.1 - 0.012 15.9 0.1 0.04 14.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAN05994.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 GAN05994.1 - 0.021 14.4 0.6 0.059 12.9 0.6 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAN05994.1 - 0.034 13.4 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Wzy_C PF04932.15 GAN05994.1 - 0.055 13.1 0.0 0.82 9.3 0.0 2.6 3 0 0 3 3 3 0 O-Antigen ligase DUF87 PF01935.17 GAN05994.1 - 0.081 13.0 1.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 GAN05994.1 - 0.13 12.0 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAN05994.1 - 0.16 12.3 0.3 0.54 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain UQ_con PF00179.26 GAN05995.1 - 3.1e-19 69.0 0.0 5.5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN05995.1 - 0.068 13.5 0.4 0.18 12.1 0.0 1.9 2 1 0 2 2 2 0 RWD domain RRM_1 PF00076.22 GAN05996.1 - 5.9e-43 144.6 0.0 8.6e-17 60.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN05996.1 - 8.7e-05 22.6 0.0 0.031 14.4 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 GAN05996.1 - 0.00049 20.1 0.3 0.0024 17.9 0.0 2.2 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 GAN05996.1 - 0.0017 18.3 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Laminin_G_2 PF02210.24 GAN05996.1 - 0.062 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Laminin G domain DUF1178 PF06676.11 GAN05996.1 - 0.1 13.0 0.5 0.19 12.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Spt5-NGN PF03439.13 GAN05997.1 - 4.5e-25 87.4 0.0 8.9e-25 86.4 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 GAN05997.1 - 9.6e-20 69.8 23.9 2e-06 27.5 0.1 7.1 7 0 0 7 7 7 4 KOW motif Spt5_N PF11942.8 GAN05997.1 - 6.5e-17 62.3 11.1 6.5e-17 62.3 11.1 2.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 GAN05997.1 - 1.3e-08 35.3 54.0 1.5e-07 31.9 40.4 3.9 1 1 1 2 2 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 GAN05997.1 - 0.038 14.2 0.0 0.67 10.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) YCII PF03795.14 GAN05997.1 - 0.084 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 YCII-related domain S1_2 PF13509.6 GAN05997.1 - 0.088 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 S1 domain PCB_OB PF17092.5 GAN05997.1 - 0.089 13.5 1.0 5.3 7.8 0.0 3.9 3 1 1 4 4 4 0 Penicillin-binding protein OB-like domain Dis3l2_C_term PF17877.1 GAN05997.1 - 0.16 12.3 2.1 9.8 6.6 0.0 3.3 1 1 1 2 2 2 0 DIS3-like exonuclease 2 C terminal DUF2187 PF09953.9 GAN05997.1 - 0.72 9.9 2.6 2.3 8.3 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) GRP PF07172.11 GAN05997.1 - 1.9 9.2 11.5 9.2 7.0 11.5 2.2 1 0 0 1 1 1 0 Glycine rich protein family PhnA PF03831.14 GAN05997.1 - 3.2 7.7 4.8 2.1 8.3 0.4 3.0 4 0 0 4 4 4 0 PhnA domain CENP-B_dimeris PF09026.10 GAN05998.1 - 0.0099 16.2 1.7 0.029 14.7 1.7 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain MBOAT PF03062.19 GAN05999.1 - 5e-50 170.8 25.7 5e-50 170.8 25.7 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family HOOK PF05622.12 GAN06000.1 - 2e-58 198.2 75.7 4.3e-56 190.5 38.5 3.2 1 1 1 2 2 2 2 HOOK protein Atg14 PF10186.9 GAN06000.1 - 0.0024 17.0 18.3 0.0024 17.0 18.3 4.4 1 1 2 4 4 4 1 Vacuolar sorting 38 and autophagy-related subunit 14 CH_2 PF06294.11 GAN06000.1 - 0.033 14.3 0.7 0.17 12.0 0.1 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein DUF4763 PF15960.5 GAN06000.1 - 0.055 12.8 0.2 0.055 12.8 0.2 5.4 4 2 1 5 5 5 0 Domain of unknown function (DUF4763) Ubiquitin_2 PF14560.6 GAN06000.1 - 0.11 13.0 2.2 0.38 11.2 1.2 2.5 1 1 1 2 2 2 0 Ubiquitin-like domain MCM_N PF14551.6 GAN06000.1 - 0.39 11.3 0.1 0.39 11.3 0.1 4.6 4 1 0 4 4 4 0 MCM N-terminal domain Filament PF00038.21 GAN06000.1 - 4.9 6.6 81.8 1.6 8.3 32.4 5.4 2 1 1 3 3 3 0 Intermediate filament protein Got1 PF04178.12 GAN06001.1 - 1.7e-32 112.2 20.8 2.4e-32 111.7 20.5 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family DUF4491 PF14898.6 GAN06001.1 - 2.9 8.4 15.4 0.44 11.0 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) 2-Hacid_dh_C PF02826.19 GAN06002.1 - 3.5e-59 199.2 0.0 4.9e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAN06002.1 - 1.2e-31 109.1 0.0 1.4e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAN06002.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 GAN06002.1 - 0.00013 21.6 0.0 0.00049 19.7 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 GAN06002.1 - 0.00078 20.0 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 GAN06002.1 - 0.0018 18.7 0.0 0.018 15.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 GAN06002.1 - 0.0049 17.0 0.1 0.013 15.5 0.1 1.7 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 GAN06002.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAN06002.1 - 0.1 12.9 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MAM33 PF02330.16 GAN06003.1 - 5.5e-74 248.7 6.9 6.4e-74 248.5 6.9 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3337 PF11816.8 GAN06004.1 - 2.3e-42 144.8 0.0 1.6e-41 142.1 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 GAN06004.1 - 1.2e-21 76.5 15.0 9.1e-07 29.5 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06004.1 - 3.2e-07 30.5 0.0 0.036 14.3 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN06004.1 - 0.0036 16.7 0.0 0.11 11.8 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 GAN06004.1 - 0.0066 15.5 0.5 0.02 13.8 0.0 2.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M24 PF00557.24 GAN06005.1 - 1.7e-52 178.2 0.8 2.7e-52 177.5 0.8 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 GAN06005.1 - 3.6e-08 34.1 0.0 6.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain WD40_3 PF15911.5 GAN06005.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat PapD-like PF14874.6 GAN06005.1 - 0.085 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like mit_SMPDase PF14724.6 GAN06006.1 - 0.00095 17.3 0.1 0.2 9.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial-associated sphingomyelin phosphodiesterase RNA_Me_trans PF04252.13 GAN06007.1 - 2.4e-78 262.3 0.0 2.7e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase GPI-anchored PF10342.9 GAN06008.1 - 0.022 15.5 0.1 0.041 14.6 0.1 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Asp PF00026.23 GAN06009.1 - 1.9e-75 254.2 3.2 2.5e-75 253.9 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN06009.1 - 2e-11 44.5 0.4 8.2e-10 39.2 0.2 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN06009.1 - 0.0054 17.3 0.0 5 7.8 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAN06009.1 - 0.09 13.3 0.0 8.6 7.0 0.0 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease RBFA PF02033.18 GAN06010.1 - 4.5e-17 62.4 0.0 8.4e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A ALIX_LYPXL_bnd PF13949.6 GAN06010.1 - 0.01 15.2 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Ribosomal_L24e PF01246.20 GAN06011.1 - 8.3e-29 99.6 0.2 1.3e-28 99.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_L4 PF00573.22 GAN06011.1 - 0.096 12.4 3.4 0.54 9.9 2.6 1.9 1 1 1 2 2 2 0 Ribosomal protein L4/L1 family Pkinase PF00069.25 GAN06012.1 - 9.7e-52 175.9 0.0 1.4e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06012.1 - 8e-35 120.4 0.0 1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAN06012.1 - 4.2e-05 23.0 0.3 7.5e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease PF00324.21 GAN06013.1 - 1.3e-116 390.1 45.0 1.5e-116 389.8 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN06013.1 - 2.2e-33 115.7 46.3 2.7e-33 115.4 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 GAN06014.1 - 7.6e-64 211.7 4.1 4.2e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN06014.1 - 0.013 14.7 0.1 0.59 9.2 0.0 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease CWC25 PF12542.8 GAN06015.1 - 1.4e-24 86.9 4.0 1.4e-24 86.9 4.0 3.1 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 GAN06015.1 - 6.2e-15 55.1 12.8 6.2e-15 55.1 12.8 3.9 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF1754 PF08555.10 GAN06015.1 - 0.011 16.5 7.1 0.011 16.5 7.1 3.2 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Lyase_1 PF00206.20 GAN06016.1 - 5.4e-102 341.4 0.0 7.3e-102 340.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 GAN06016.1 - 1.5e-23 83.4 1.5 2.8e-23 82.4 0.1 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal MFS_1 PF07690.16 GAN06017.1 - 6.6e-22 77.9 35.9 1.3e-18 67.1 19.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Ac76 PF05814.11 GAN06017.1 - 0.45 10.6 4.4 0.23 11.5 0.4 2.7 2 0 0 2 2 2 0 Orf76 (Ac76) P16-Arc PF04699.14 GAN06018.1 - 5.3e-53 179.5 0.1 6e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 GAN06018.1 - 0.036 14.4 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family Pkinase PF00069.25 GAN06019.1 - 1.6e-66 224.4 0.0 2.3e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06019.1 - 4.5e-28 98.2 0.0 5.9e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN06019.1 - 6e-07 29.1 0.1 0.00018 20.9 0.0 2.2 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 GAN06019.1 - 0.0011 18.6 0.2 0.0011 18.6 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 GAN06019.1 - 0.0064 15.9 0.4 0.012 15.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN06019.1 - 0.016 14.1 0.1 0.039 12.9 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain PRP38_assoc PF12871.7 GAN06019.1 - 0.021 15.4 3.5 0.038 14.6 3.5 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term APH PF01636.23 GAN06019.1 - 0.11 12.4 0.2 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cdh1_DBD_1 PF18196.1 GAN06019.1 - 1.1 9.6 6.2 1.8 8.9 6.2 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DSPc PF00782.20 GAN06020.1 - 7.3e-34 116.4 0.0 8.9e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN06020.1 - 0.00031 20.4 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 GAN06020.1 - 0.051 13.9 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Chs7 PF12271.8 GAN06021.1 - 1.2e-114 382.6 23.3 1.4e-114 382.4 23.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2070 PF09843.9 GAN06021.1 - 9.3 4.4 21.9 12 4.0 21.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HsbA PF12296.8 GAN06022.1 - 2e-05 25.0 0.1 2.5e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A ELF PF03317.13 GAN06023.1 - 0.037 14.0 2.4 0.079 13.0 1.1 2.2 3 0 0 3 3 3 0 ELF protein DUF1891 PF09004.10 GAN06023.1 - 0.65 9.6 2.9 1.1 8.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) HsbA PF12296.8 GAN06024.1 - 0.021 15.3 0.2 0.04 14.3 0.1 1.6 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF1539 PF07560.11 GAN06025.1 - 0.0096 16.0 1.7 0.02 15.0 0.2 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) Aldedh PF00171.22 GAN06026.1 - 6.7e-131 437.0 0.1 8.7e-131 436.6 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family XRN_M PF17846.1 GAN06026.1 - 2e-97 327.0 7.7 5.8e-97 325.4 7.6 1.7 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 GAN06026.1 - 2.3e-90 302.3 0.1 7.1e-90 300.7 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 GAN06026.1 - 6.4e-64 215.3 0.1 1.6e-63 214.0 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 GAN06026.1 - 8.6e-23 80.2 2.2 1.6e-22 79.4 0.7 2.2 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 GAN06026.1 - 1.1e-19 70.5 0.1 1.6e-18 66.7 0.0 3.0 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D2/D3 domain LuxC PF05893.14 GAN06026.1 - 0.04 13.0 0.0 0.093 11.8 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DMAP_binding PF06464.11 GAN06027.1 - 5.6e-11 43.2 0.4 5.6e-11 43.2 0.4 3.3 4 1 0 4 4 4 1 DMAP1-binding Domain GvpG PF05120.12 GAN06027.1 - 0.00092 19.2 0.1 0.0021 18.0 0.1 1.7 1 0 0 1 1 1 1 Gas vesicle protein G AMP-binding PF00501.28 GAN06028.1 - 2.9e-64 217.2 3.5 5.6e-39 133.9 1.0 4.1 3 2 0 3 3 3 3 AMP-binding enzyme Acetyltransf_1 PF00583.25 GAN06029.1 - 1.5e-11 44.5 0.0 2.3e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN06029.1 - 3.6e-09 36.6 0.0 7.5e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN06029.1 - 1.3e-08 35.1 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAN06029.1 - 2.6e-05 24.3 0.0 7.3e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAN06029.1 - 0.00011 21.7 0.0 0.00041 19.9 0.0 1.8 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 GAN06029.1 - 0.0058 16.7 0.0 0.01 16.0 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 GAN06029.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 GAN06029.1 - 0.14 12.1 0.0 0.42 10.6 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Cupin_8 PF13621.6 GAN06030.1 - 9.4e-67 225.4 0.6 1.2e-58 198.9 0.0 2.0 2 0 0 2 2 2 2 Cupin-like domain Thaumatin PF00314.17 GAN06031.1 - 1e-46 159.3 14.6 5.3e-46 157.0 14.6 1.8 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 GAN06031.1 - 0.0012 18.2 1.5 0.06 12.6 0.0 2.3 2 1 0 2 2 2 2 Beta-1,3-glucanase Ribosomal_L27e PF01777.18 GAN06032.1 - 6e-37 125.9 7.4 6e-37 125.9 7.4 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 GAN06032.1 - 0.0027 17.6 6.5 0.0071 16.3 6.5 2.0 1 1 0 1 1 1 1 KOW motif FKBP_C PF00254.28 GAN06033.1 - 4.3e-30 103.9 0.1 1.9e-29 101.8 0.0 2.1 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 GAN06033.1 - 2.6e-26 92.2 0.1 2.6e-26 92.2 0.1 3.0 2 1 0 2 2 1 1 Nucleoplasmin-like domain PAT1 PF09770.9 GAN06033.1 - 0.4 8.9 17.7 0.51 8.5 17.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pro-rich PF15240.6 GAN06033.1 - 1.7 8.9 21.8 3.1 8.1 21.8 1.3 1 0 0 1 1 1 0 Proline-rich Presenilin PF01080.17 GAN06033.1 - 1.9 7.1 16.9 2.7 6.6 16.9 1.3 1 0 0 1 1 1 0 Presenilin FAM220 PF15487.6 GAN06033.1 - 3.8 7.1 10.5 5.9 6.4 10.5 1.4 1 0 0 1 1 1 0 FAM220 family DUF4045 PF13254.6 GAN06033.1 - 4.1 6.9 29.9 5.7 6.5 29.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 GAN06033.1 - 7.2 5.5 17.3 10 5.0 17.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CCSAP PF15748.5 GAN06033.1 - 7.8 6.6 28.5 11 6.1 28.5 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Red1 PF07964.11 GAN06033.1 - 9.4 4.3 29.9 12 3.9 29.9 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Ndc1_Nup PF09531.10 GAN06033.1 - 9.6 4.8 10.9 12 4.4 10.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RhoGAP PF00620.27 GAN06035.1 - 4.1e-52 176.1 0.1 4.1e-52 176.1 0.1 2.5 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 GAN06035.1 - 9.4e-18 64.2 37.9 4.3e-10 39.7 6.6 3.5 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 GAN06035.1 - 8.6e-07 28.7 11.2 8.6e-07 28.7 11.2 4.6 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) CENP-F_leu_zip PF10473.9 GAN06035.1 - 0.024 14.7 23.2 0.027 14.5 0.8 3.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 GAN06035.1 - 0.22 10.8 27.9 0.6 9.4 11.9 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Lip_prot_lig_C PF10437.9 GAN06035.1 - 0.44 10.6 2.5 1.8 8.6 0.1 3.1 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus DivIC PF04977.15 GAN06035.1 - 1.1 9.0 14.5 3.1 7.6 0.2 3.8 3 1 0 3 3 3 0 Septum formation initiator SOAR PF16533.5 GAN06035.1 - 3.4 7.7 13.3 1.4 9.0 0.5 4.1 3 1 0 4 4 4 0 STIM1 Orai1-activating region CALCOCO1 PF07888.11 GAN06035.1 - 3.5 6.4 26.0 26 3.5 26.0 2.1 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 GAN06035.1 - 4.7 7.3 24.9 2.5 8.2 4.5 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 GAN06035.1 - 9.3 6.3 16.7 3 7.8 1.2 4.1 2 1 1 3 3 3 0 Prefoldin subunit MFS_1 PF07690.16 GAN06036.1 - 1.9e-46 158.6 24.0 5.1e-45 153.9 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN06036.1 - 1.9e-10 40.2 9.7 1.9e-10 40.2 9.7 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 GAN06036.1 - 2.6e-08 33.5 3.0 2.6e-08 33.5 3.0 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1772 PF08592.11 GAN06036.1 - 0.0085 16.4 8.4 0.17 12.2 0.0 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) RseC_MucC PF04246.12 GAN06036.1 - 2.7 7.9 0.0 2.7 7.9 0.0 4.3 4 2 1 5 5 5 0 Positive regulator of sigma(E), RseC/MucC Gpi16 PF04113.14 GAN06037.1 - 1.3e-181 604.8 0.4 2e-180 601.0 0.4 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component BCDHK_Adom3 PF10436.9 GAN06038.1 - 2.9e-59 199.6 0.1 4.2e-59 199.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAN06038.1 - 5.8e-13 49.3 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAN06038.1 - 0.0007 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 GAN06038.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family HLH PF00010.26 GAN06040.1 - 1.8e-12 47.0 0.2 4.5e-12 45.7 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mucin-like PF16058.5 GAN06041.1 - 0.042 13.9 3.4 0.09 12.9 3.4 1.5 1 0 0 1 1 1 0 Mucin-like DUF4045 PF13254.6 GAN06041.1 - 0.073 12.7 3.6 0.1 12.2 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Radical_SAM PF04055.21 GAN06042.1 - 1.4e-12 48.3 0.0 2.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 GAN06042.1 - 0.00013 22.0 0.9 0.00062 19.8 0.4 2.4 1 1 1 2 2 2 1 HemN C-terminal domain ERO1 PF04137.15 GAN06043.1 - 5.3e-134 446.9 0.6 6.8e-134 446.5 0.6 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PXA PF02194.15 GAN06044.1 - 6.7e-46 156.6 3.0 1.4e-45 155.5 1.4 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 GAN06044.1 - 1.5e-26 93.1 0.4 1.5e-26 93.1 0.4 3.7 4 0 0 4 4 4 1 Sorting nexin C terminal PX PF00787.24 GAN06044.1 - 4.9e-19 68.4 2.6 5.7e-19 68.2 0.0 2.6 2 0 0 2 2 2 1 PX domain RGS PF00615.19 GAN06044.1 - 8.9e-16 58.2 4.6 5.4e-14 52.5 4.2 3.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain Rbsn PF11464.8 GAN06044.1 - 0.012 15.4 3.0 0.034 13.9 3.0 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain RNA_pol_3_Rpc31 PF11705.8 GAN06044.1 - 0.57 10.4 20.6 3 8.0 13.4 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 GAN06044.1 - 1 9.0 17.3 0.28 10.8 3.4 3.3 3 0 0 3 3 3 0 FAM176 family SSP160 PF06933.11 GAN06044.1 - 1.5 6.9 13.8 0.13 10.4 8.3 1.9 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF2207 PF09972.9 GAN06045.1 - 0.15 10.8 0.1 0.17 10.6 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) tRNA_m1G_MT PF01746.21 GAN06046.1 - 1.3e-30 106.6 0.1 1.8e-30 106.1 0.1 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Peptidase_M61 PF05299.12 GAN06046.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Pyr_redox_2 PF07992.14 GAN06047.1 - 9.5e-42 143.2 0.0 1.5e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 GAN06047.1 - 6.7e-21 74.4 7.7 2.4e-19 69.4 1.2 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 GAN06047.1 - 8.2e-21 73.9 0.0 7.4e-20 70.8 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 GAN06047.1 - 2.9e-18 65.9 0.0 6.1e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 GAN06047.1 - 6.2e-13 49.1 0.0 2.4e-12 47.2 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 GAN06047.1 - 1.9e-11 43.7 0.0 4.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 GAN06047.1 - 6.6e-09 35.6 0.1 6.6e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Rieske PF00355.26 GAN06047.1 - 2.2e-08 33.9 0.0 5.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain AlaDh_PNT_C PF01262.21 GAN06047.1 - 0.0005 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 GAN06047.1 - 0.011 14.8 0.1 0.52 9.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 GAN06047.1 - 0.021 15.1 0.1 0.056 13.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAN06047.1 - 0.026 13.6 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAN06047.1 - 0.031 14.3 0.0 2.2 8.3 0.0 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding AAA_32 PF13654.6 GAN06047.1 - 0.24 10.1 0.2 7.6 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Oxidored_molyb PF00174.19 GAN06048.1 - 4.3e-59 199.0 0.0 1.9e-58 196.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAN06048.1 - 1.1e-41 142.1 0.6 1.8e-41 141.4 0.6 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 GAN06048.1 - 1.7e-22 79.3 0.1 4.6e-22 77.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 GAN06048.1 - 6.6e-18 64.9 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAN06048.1 - 2e-17 63.8 0.0 4.5e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAN06048.1 - 0.0016 18.6 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain HOOK PF05622.12 GAN06049.1 - 5e-68 229.9 88.3 8.2e-61 206.1 61.4 2.2 1 1 1 2 2 2 2 HOOK protein CH_2 PF06294.11 GAN06049.1 - 0.065 13.4 0.1 0.065 13.4 0.1 3.1 3 1 0 3 3 3 0 CH-like domain in sperm protein Inhibitor_G39P PF11417.8 GAN06049.1 - 0.082 13.4 0.0 0.34 11.5 0.0 2.1 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P CNH PF00780.22 GAN06050.1 - 4.2e-57 193.9 0.3 7.6e-56 189.7 0.3 2.4 1 1 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAN06050.1 - 1.8e-36 126.1 3.0 4.2e-36 124.9 3.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 GAN06050.1 - 2.8e-31 108.4 0.5 3.6e-30 104.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 GAN06050.1 - 9.7e-12 44.8 0.1 4.8e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RRM_1 PF00076.22 GAN06050.1 - 0.077 12.8 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.10 GAN06050.1 - 0.22 11.9 22.9 0.32 11.4 15.4 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GAN06050.1 - 0.53 10.0 10.6 1.6 8.4 4.3 2.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GAN06050.1 - 3.5 7.6 9.8 0.45 10.5 2.1 3.2 3 0 0 3 3 3 0 RXT2-like, N-terminal HSP70 PF00012.20 GAN06051.1 - 2.7e-06 25.9 0.0 4.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein Zn_clus PF00172.18 GAN06052.1 - 1.5e-08 34.6 17.5 2.7e-08 33.8 17.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC117 PF15810.5 GAN06052.1 - 5.2 7.4 10.0 7.6 6.8 0.3 4.5 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 117 Arrestin_N PF00339.29 GAN06053.1 - 7.6e-09 35.8 0.0 9.6e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN06053.1 - 2.9e-08 34.2 0.1 6.7e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 GAN06053.1 - 0.13 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Arrestin_N terminal like UDPGP PF01704.18 GAN06054.1 - 3e-57 194.1 0.0 4.5e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 GAN06054.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Peptidase_S8 PF00082.22 GAN06055.1 - 3.3e-43 148.0 6.9 5.5e-43 147.3 6.9 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 GAN06055.1 - 1.1e-09 39.0 0.4 1.1e-09 39.0 0.4 2.8 3 1 1 4 4 4 1 Fn3-like domain PA PF02225.22 GAN06055.1 - 7.6e-09 35.5 0.0 2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF4434 PF14488.6 GAN06055.1 - 0.036 14.1 0.3 9 6.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) Tenui_NS4 PF03300.13 GAN06055.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Tenuivirus non-structural, movement protein NS4 CNH PF00780.22 GAN06056.1 - 2.4e-55 188.1 0.1 5.6e-55 186.9 0.0 1.6 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 GAN06056.1 - 1e-35 123.7 6.0 1e-35 123.6 4.0 2.1 1 1 1 2 2 2 1 RhoGEF domain PH_5 PF15405.6 GAN06056.1 - 4.7e-19 68.8 0.0 1.6e-18 67.1 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 GAN06056.1 - 0.042 13.7 0.1 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain DUF4203 PF13886.6 GAN06057.1 - 7.4e-20 71.5 32.8 1.7e-18 67.0 32.6 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) NnrS PF05940.12 GAN06058.1 - 0.056 12.8 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 NnrS protein Pkinase PF00069.25 GAN06059.1 - 1.2e-64 218.2 0.1 3e-64 216.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06059.1 - 2.1e-43 148.5 0.0 4.4e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAN06059.1 - 0.00012 21.5 0.2 0.00025 20.5 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAN06059.1 - 0.00016 21.1 0.1 0.00058 19.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAN06059.1 - 0.0064 16.4 0.3 3.2 7.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family YabA PF06156.13 GAN06059.1 - 0.63 10.7 6.5 2.8 8.6 0.0 3.4 3 0 0 3 3 3 0 Initiation control protein YabA Ank_2 PF12796.7 GAN06060.1 - 1.1e-23 83.6 0.1 1.1e-14 54.8 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN06060.1 - 6.7e-19 66.0 0.1 6.8e-06 26.1 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 GAN06060.1 - 7.6e-15 54.6 1.8 0.0011 19.3 0.0 6.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 GAN06060.1 - 6.4e-14 51.8 0.2 0.00079 19.7 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN06060.1 - 1.2e-12 48.1 0.1 8.4e-05 23.0 0.3 4.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DBINO PF13892.6 GAN06060.1 - 0.21 11.9 4.8 0.22 11.9 2.6 2.1 1 1 1 2 2 2 0 DNA-binding domain GatB_Yqey PF02637.18 GAN06060.1 - 0.72 9.7 3.6 1.4 8.8 3.6 1.4 1 0 0 1 1 1 0 GatB domain Cupin_8 PF13621.6 GAN06062.1 - 2.1e-19 70.3 5.7 3.4e-19 69.6 5.7 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 GAN06062.1 - 7.7e-15 55.3 3.6 1.4e-14 54.5 1.9 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase GPI PF06560.11 GAN06062.1 - 0.093 12.0 0.1 0.28 10.4 0.1 1.8 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) SpoU_methylase PF00588.19 GAN06063.1 - 3.9e-22 78.9 0.0 6.3e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SRF-TF PF00319.18 GAN06064.1 - 1.6e-21 75.5 0.0 2.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SNF5 PF04855.12 GAN06065.1 - 2.3e-55 188.0 5.4 5.9e-30 104.8 0.5 2.5 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 HA2 PF04408.23 GAN06065.1 - 7.1e-24 84.2 0.0 7.1e-24 84.2 0.0 2.9 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAN06065.1 - 3.5e-15 56.3 0.0 1.2e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAN06065.1 - 7.6e-13 48.6 0.0 2.2e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAN06065.1 - 2.9e-09 36.9 0.4 7.5e-09 35.6 0.4 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAN06065.1 - 0.00053 20.3 0.1 0.0023 18.2 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN06065.1 - 0.0017 18.7 0.2 0.004 17.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAN06065.1 - 0.0036 17.0 0.1 0.0073 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAN06065.1 - 0.021 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 GAN06065.1 - 0.023 14.0 0.1 0.072 12.4 0.0 1.8 2 0 0 2 2 2 0 KaiC Herpes_ori_bp PF02399.15 GAN06065.1 - 0.035 12.2 0.1 0.055 11.5 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Flavi_DEAD PF07652.14 GAN06065.1 - 0.038 14.0 0.1 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain Kinesin PF00225.23 GAN06065.1 - 0.044 12.7 0.5 0.081 11.8 0.5 1.3 1 0 0 1 1 1 0 Kinesin motor domain ABC_tran PF00005.27 GAN06065.1 - 0.076 13.5 1.8 0.67 10.5 0.3 3.0 2 1 0 2 2 1 0 ABC transporter PhoH PF02562.16 GAN06065.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 GAN06065.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 GAN06065.1 - 5.2 6.2 6.5 0.2 10.8 0.1 1.9 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L32e PF01655.18 GAN06066.1 - 9.9e-49 164.3 0.5 1.4e-48 163.8 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 Pro_isomerase PF00160.21 GAN06067.1 - 7e-38 130.4 0.3 9.1e-38 130.0 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Patched PF02460.18 GAN06068.1 - 0.2 9.7 1.5 0.22 9.6 1.5 1.0 1 0 0 1 1 1 0 Patched family SCIMP PF15050.6 GAN06068.1 - 2 8.9 4.2 0.22 12.0 0.4 1.4 2 0 0 2 2 2 0 SCIMP protein Elongin_A PF06881.11 GAN06069.1 - 1.8e-24 86.3 3.7 1.8e-24 86.3 3.7 2.5 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF5057 PF16480.5 GAN06069.1 - 0.027 13.8 0.5 0.04 13.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5057) DUF2852 PF11014.8 GAN06069.1 - 0.28 11.3 1.3 0.61 10.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Histone PF00125.24 GAN06070.1 - 1.1e-16 61.4 0.0 1.3e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 GAN06070.1 - 7.4e-12 44.8 0.8 1.6e-11 43.7 0.8 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 GAN06070.1 - 0.00019 21.7 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myosin_head PF00063.21 GAN06071.1 - 8e-244 810.9 0.8 9.9e-244 810.6 0.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAN06071.1 - 4e-46 157.1 0.1 6.4e-46 156.4 0.1 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAN06071.1 - 2.3e-14 52.7 0.6 4.6e-14 51.7 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN06071.1 - 9.9e-12 44.5 0.1 2.6e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN06071.1 - 3.1e-10 39.6 0.0 9.3e-10 38.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 GAN06071.1 - 0.00032 20.9 0.4 0.00083 19.6 0.4 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.6 GAN06071.1 - 0.018 15.3 0.0 0.054 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 GAN06071.1 - 0.029 13.9 0.3 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain FGGY_N PF00370.21 GAN06071.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain NACHT PF05729.12 GAN06071.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GAN06071.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.27 GAN06071.1 - 0.24 11.3 10.1 1.9 8.5 1.5 3.3 3 0 0 3 3 3 0 IQ calmodulin-binding motif FAR1 PF03101.15 GAN06072.1 - 6.8e-08 33.1 2.2 1.7e-07 31.8 2.2 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain TTL PF03133.15 GAN06073.1 - 3.7e-54 183.9 3.2 3.7e-54 183.9 3.2 2.5 3 0 0 3 3 3 1 Tubulin-tyrosine ligase family APOBEC_C PF05240.14 GAN06073.1 - 0.093 12.7 1.4 0.32 11.0 1.4 1.9 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ATPgrasp_ST PF14397.6 GAN06073.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Plasmodium_Vir PF05795.11 GAN06075.1 - 0.0085 15.6 0.5 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Plasmodium vivax Vir protein Not1 PF04054.15 GAN06076.1 - 1.9e-147 491.0 1.1 6.5e-147 489.3 1.1 2.0 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAN06076.1 - 3.4e-94 314.4 6.5 9.7e-94 312.9 6.5 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 GAN06076.1 - 6.4e-70 234.2 1.2 2.1e-69 232.5 0.0 2.5 1 1 1 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 GAN06076.1 - 2.5e-54 183.2 10.9 2.5e-54 183.2 6.7 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 GAN06076.1 - 4.1e-43 147.0 1.8 4.1e-43 147.0 1.8 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Pkinase PF00069.25 GAN06077.1 - 4.1e-71 239.4 0.0 5.5e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06077.1 - 9.2e-32 110.3 0.0 1.2e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN06077.1 - 1.1e-08 34.7 0.5 4.2e-06 26.3 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 GAN06077.1 - 5.5e-05 22.3 0.8 9.2e-05 21.5 0.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 GAN06077.1 - 0.0038 16.9 0.5 0.55 9.8 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GAN06077.1 - 0.0056 16.3 1.7 0.079 12.5 1.7 2.1 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 GAN06077.1 - 0.0095 15.9 0.1 0.49 10.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family N6_N4_Mtase PF01555.18 GAN06077.1 - 0.095 12.4 1.1 0.21 11.3 1.1 1.5 1 0 0 1 1 1 0 DNA methylase PH PF00169.29 GAN06078.1 - 4e-09 36.9 0.2 9.9e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAN06078.1 - 1.6e-08 34.9 0.2 6.3e-08 33.0 0.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain DDE_3 PF13358.6 GAN06079.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 1 1 2 2 2 0 DDE superfamily endonuclease TFIIS_M PF07500.14 GAN06081.1 - 5.4e-24 84.8 0.4 5.4e-24 84.8 0.4 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 GAN06081.1 - 6.1e-16 58.7 0.0 1.4e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 GAN06081.1 - 9.5e-11 41.4 13.7 2.1e-10 40.3 13.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAN06081.1 - 0.00027 20.4 5.5 0.00049 19.6 5.5 1.5 1 0 0 1 1 1 1 PHD-finger IF-2B PF01008.17 GAN06082.1 - 5.6e-72 242.3 3.4 6.6e-72 242.1 3.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Flavodoxin_2 PF02525.17 GAN06083.1 - 5.3e-23 81.8 0.1 6.2e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 GAN06083.1 - 1.1e-05 25.2 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase TetR_C_9 PF14514.6 GAN06083.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sugar_tr PF00083.24 GAN06085.1 - 5.8e-75 252.9 27.6 7.2e-75 252.6 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN06085.1 - 1.2e-16 60.7 33.8 2e-15 56.6 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arv1 PF04161.13 GAN06086.1 - 4.5e-58 196.9 12.6 5.1e-58 196.7 12.6 1.0 1 0 0 1 1 1 1 Arv1-like family Herpes_MCP PF03122.14 GAN06086.1 - 0.011 13.2 2.5 0.014 12.9 2.5 1.1 1 0 0 1 1 1 0 Herpes virus major capsid protein 4HBT PF03061.22 GAN06087.1 - 1.7e-30 105.2 0.9 1.9e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily NAD_Gly3P_dh_C PF07479.14 GAN06087.1 - 0.12 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus RsgA_N PF16745.5 GAN06087.1 - 0.34 10.7 0.9 34 4.3 0.0 3.2 4 0 0 4 4 4 0 RsgA N-terminal domain THF_DHG_CYH PF00763.23 GAN06088.1 - 4e-26 91.5 0.1 1.3e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAN06088.1 - 2.7e-14 52.8 0.4 6e-13 48.4 0.4 2.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 GAN06088.1 - 0.0039 16.8 0.7 0.14 11.7 0.7 2.5 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DpaA_N PF16924.5 GAN06088.1 - 0.085 13.0 0.1 0.38 10.8 0.0 2.2 2 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain AlaDh_PNT_C PF01262.21 GAN06088.1 - 0.096 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tubulin PF00091.25 GAN06089.1 - 2.4e-68 230.3 0.0 3.8e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAN06089.1 - 2.8e-45 153.5 0.3 1.1e-44 151.6 0.1 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAN06089.1 - 2.6e-05 24.5 0.0 6.5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 GAN06089.1 - 0.0022 17.7 0.1 0.0061 16.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Tubulin_2 PF13809.6 GAN06089.1 - 0.068 12.4 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin like UPF0669 PF17065.5 GAN06089.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 DUF4423 PF14394.6 GAN06090.1 - 0.018 14.8 1.5 0.058 13.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) HBD PF18534.1 GAN06090.1 - 0.033 14.3 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Helical bundle domain Cyclin_N PF00134.23 GAN06090.1 - 0.062 13.0 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain FAM199X PF15814.5 GAN06090.1 - 0.47 9.4 13.5 0.027 13.5 5.2 2.1 2 0 0 2 2 2 0 Protein family FAM199X CFIA_Pcf11 PF11526.8 GAN06090.1 - 0.55 10.8 6.1 1.6 9.2 0.8 2.3 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 FSA_C PF10479.9 GAN06090.1 - 0.91 7.6 13.7 4.1 5.4 0.2 2.1 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus SPX PF03105.19 GAN06090.1 - 0.97 9.3 15.2 1.4 8.8 15.2 1.1 1 0 0 1 1 1 0 SPX domain Cyclin PF08613.11 GAN06090.1 - 1 9.7 16.3 1.5 9.1 0.1 3.3 2 1 1 3 3 3 0 Cyclin SSP160 PF06933.11 GAN06090.1 - 1.1 7.4 31.0 0.043 12.0 15.0 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 SprA-related PF12118.8 GAN06090.1 - 3.7 6.6 16.9 0.25 10.5 7.6 2.1 2 0 0 2 2 2 0 SprA-related family Lipase_GDSL PF00657.22 GAN06091.1 - 0.074 13.0 0.2 0.4 10.6 0.1 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN06091.1 - 0.17 12.3 0.0 0.48 10.8 0.0 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ING PF12998.7 GAN06093.1 - 3.3e-21 75.7 1.3 9.8e-21 74.2 1.3 1.9 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Fungal_trans PF04082.18 GAN06093.1 - 5.6e-07 28.9 2.6 1e-06 28.0 2.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.29 GAN06093.1 - 0.0016 18.3 7.9 0.0046 16.8 7.9 1.8 1 0 0 1 1 1 1 PHD-finger DUF3325 PF11804.8 GAN06093.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) zf-HC5HC2H_2 PF13832.6 GAN06093.1 - 0.21 11.8 3.1 0.9 9.7 0.4 2.6 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAN06093.1 - 0.32 11.3 3.0 0.36 11.1 0.7 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain BRE1 PF08647.11 GAN06093.1 - 0.5 10.5 9.3 3 8.0 0.1 3.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase BCIP PF13862.6 GAN06094.1 - 3.5e-67 226.2 2.0 4.8e-67 225.7 2.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.32 GAN06095.1 - 3.2e-13 49.9 12.5 0.016 16.1 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat LisH PF08513.11 GAN06095.1 - 0.00012 21.9 0.3 0.00034 20.4 0.1 1.9 2 0 0 2 2 2 1 LisH AlbA_2 PF04326.14 GAN06095.1 - 0.17 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain DUF3094 PF11293.8 GAN06096.1 - 2.9 7.7 4.7 14 5.5 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3094) RNA_pol_I_A49 PF06870.12 GAN06097.1 - 2.6e-98 329.4 3.9 3e-98 329.2 3.9 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Methyltransf_25 PF13649.6 GAN06098.1 - 1.2e-12 48.4 0.0 2.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN06098.1 - 5.4e-12 45.8 0.0 9.7e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAN06098.1 - 1.4e-10 41.0 0.1 2.1e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAN06098.1 - 8.7e-10 39.1 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN06098.1 - 2.8e-07 30.5 0.0 7.9e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAN06098.1 - 1.3e-06 27.6 0.1 1.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 GAN06098.1 - 8.2e-06 26.5 0.0 1.8e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN06098.1 - 2.2e-05 24.1 0.2 3.6e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAN06098.1 - 2.9e-05 23.5 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 GAN06098.1 - 8.3e-05 22.6 0.3 0.00014 21.9 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAN06098.1 - 0.0055 17.7 0.0 0.012 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAN06098.1 - 0.0059 16.6 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 GAN06098.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.19 GAN06098.1 - 0.0097 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAN06098.1 - 0.017 14.5 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_M54 PF07998.11 GAN06098.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M54 Methyltransf_16 PF10294.9 GAN06098.1 - 0.075 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 GAN06098.1 - 0.077 12.4 0.8 0.25 10.7 0.8 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.13 GAN06098.1 - 0.08 12.5 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 PCMT PF01135.19 GAN06098.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SDF PF00375.18 GAN06099.1 - 1.8e-102 343.3 37.4 2.1e-102 343.1 37.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Diacid_rec PF05651.13 GAN06099.1 - 0.16 11.7 0.5 19 4.9 0.3 2.6 2 0 0 2 2 2 0 Putative sugar diacid recognition F-box-like PF12937.7 GAN06100.1 - 1.5e-05 24.8 0.5 3.2e-05 23.7 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GAN06100.1 - 4.5e-05 23.3 0.2 0.00033 20.5 0.0 2.2 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 GAN06100.1 - 0.0096 16.3 1.9 3 8.4 0.0 3.7 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN06100.1 - 0.08 12.8 1.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 F-box domain GATA PF00320.27 GAN06101.1 - 4.1e-21 74.3 16.2 1.2e-16 60.0 5.3 2.3 2 0 0 2 2 2 2 GATA zinc finger Cytochrom_c3_2 PF14537.6 GAN06101.1 - 0.025 15.0 12.1 0.87 10.1 2.3 2.4 2 0 0 2 2 2 0 Cytochrome c3 Cytochrom_CIII PF02085.16 GAN06101.1 - 0.098 13.0 6.2 0.58 10.5 0.6 2.5 2 0 0 2 2 2 0 Class III cytochrome C family TDP43_N PF18694.1 GAN06101.1 - 0.19 11.6 0.1 0.43 10.5 0.1 1.5 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain Cytochrome_CBB3 PF13442.6 GAN06101.1 - 0.37 11.2 2.4 0.72 10.2 0.1 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Zn-ribbon_8 PF09723.10 GAN06101.1 - 0.38 10.9 5.5 4.6 7.5 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 GAN06101.1 - 1.2 9.0 7.7 8.7 6.3 1.5 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 GAN06101.1 - 1.3 8.6 3.9 1.5 8.4 0.3 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Cytochrome_C7 PF14522.6 GAN06101.1 - 1.3 9.0 10.4 2 8.5 0.9 2.7 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrome_C554 PF13435.6 GAN06101.1 - 1.6 9.7 9.9 1.8 9.5 0.7 2.8 2 1 1 3 3 3 0 Cytochrome c554 and c-prime AA_permease_2 PF13520.6 GAN06102.1 - 5.2e-61 206.8 57.3 1.1e-60 205.7 57.3 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN06102.1 - 8.4e-31 107.1 44.4 1.3e-30 106.5 44.4 1.2 1 0 0 1 1 1 1 Amino acid permease PDR_assoc PF08370.11 GAN06102.1 - 1.7 8.4 7.3 4.7 7.0 0.2 3.2 3 0 0 3 3 3 0 Plant PDR ABC transporter associated VIT1 PF01988.19 GAN06102.1 - 8 6.3 9.8 0.42 10.5 0.1 3.0 3 0 0 3 3 3 0 VIT family Acyl-CoA_dh_1 PF00441.24 GAN06103.1 - 1.7e-45 154.9 4.1 1.7e-45 154.9 4.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAN06103.1 - 5.1e-24 85.1 0.1 3e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAN06103.1 - 2.9e-23 81.9 0.0 5.9e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAN06103.1 - 2e-19 70.2 1.2 2e-19 70.2 1.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAN06103.1 - 0.051 13.2 0.1 0.17 11.5 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 GAN06103.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Staphylococcal AgrD protein Clathrin PF00637.20 GAN06104.1 - 6.8e-211 690.6 47.1 1.7e-38 131.7 1.4 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 GAN06104.1 - 1.6e-33 113.4 1.1 3e-06 27.3 0.0 6.8 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 GAN06104.1 - 4e-31 106.7 0.3 4.8e-30 103.3 0.1 3.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 GAN06104.1 - 1.8e-12 46.4 1.5 5.6e-12 44.8 1.5 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 GAN06104.1 - 4.1e-10 39.3 9.0 1.3e-05 24.5 0.1 4.5 4 0 0 4 4 4 3 Coatomer WD associated region TPR_14 PF13428.6 GAN06104.1 - 4.1e-05 24.1 7.6 6.6 7.8 0.0 8.7 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN06104.1 - 0.0011 18.9 9.4 6.2 7.2 0.0 7.4 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06104.1 - 0.0019 18.6 9.4 0.52 10.8 0.1 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAN06104.1 - 0.0024 17.6 10.7 2.2 8.3 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN06104.1 - 0.11 12.7 4.9 27 5.3 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN06104.1 - 0.22 11.9 5.4 80 3.6 0.0 5.2 6 1 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN06104.1 - 0.23 11.7 3.5 21 5.4 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 GAN06104.1 - 4.6 7.7 6.8 35 4.9 0.0 5.3 8 0 0 8 8 7 0 PPR repeat TPR_7 PF13176.6 GAN06104.1 - 6.5 7.0 15.1 29 5.0 0.0 7.3 9 0 0 9 9 8 0 Tetratricopeptide repeat Hormone_3 PF00159.18 GAN06105.1 - 0.091 12.9 0.2 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Pancreatic hormone peptide RRM_1 PF00076.22 GAN06106.1 - 1.2e-30 105.1 3.4 1.2e-17 63.5 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN06106.1 - 0.011 15.8 0.1 7.7 6.7 0.0 3.3 2 1 1 3 3 3 0 RNA recognition motif efb-c PF12199.8 GAN06106.1 - 0.48 10.5 5.9 1.7 8.8 0.3 2.8 1 1 2 3 3 3 0 Extracellular fibrinogen binding protein C terminal Retrotrans_gag PF03732.17 GAN06107.1 - 0.072 13.4 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3138 PF11336.8 GAN06107.1 - 0.28 9.8 1.9 0.44 9.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2514 PF10721.9 GAN06107.1 - 0.34 10.9 4.7 0.75 9.8 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Glyco_transf_20 PF00982.21 GAN06108.1 - 5.8e-151 503.4 0.0 8.3e-151 502.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN06108.1 - 1.9e-72 243.2 0.0 3.4e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 GAN06108.1 - 1.2e-05 25.2 0.0 0.012 15.4 0.1 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Nicastrin PF05450.15 GAN06109.1 - 1e-33 116.8 5.8 2.7e-33 115.4 2.7 2.7 2 1 0 2 2 2 1 Nicastrin Ncstrn_small PF18266.1 GAN06109.1 - 6.3e-30 104.4 0.0 5.3e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 Nicastrin small lobe Peptidase_M28 PF04389.17 GAN06109.1 - 3e-05 23.8 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 FHA PF00498.26 GAN06110.1 - 6.4e-09 36.0 0.2 1.3e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 FHA domain Snf7 PF03357.21 GAN06111.1 - 2.9e-41 141.0 28.2 3.3e-41 140.8 20.9 2.1 2 0 0 2 2 2 1 Snf7 NPV_P10 PF05531.12 GAN06111.1 - 0.0029 18.0 17.1 0.0058 17.1 3.7 3.4 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein SNAD3 PF18749.1 GAN06111.1 - 0.076 12.2 4.6 0.1 11.8 4.6 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Hydantoinase_B PF02538.14 GAN06111.1 - 0.086 11.2 2.6 0.11 10.9 2.6 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase FlaC_arch PF05377.11 GAN06111.1 - 0.12 12.7 12.2 0.41 11.1 0.1 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) YlbE PF14003.6 GAN06111.1 - 0.19 12.2 4.0 0.48 10.9 1.0 2.6 2 0 0 2 2 2 0 YlbE-like protein Prefoldin_2 PF01920.20 GAN06111.1 - 0.75 9.8 0.0 0.75 9.8 0.0 4.1 3 1 0 3 3 2 0 Prefoldin subunit zf-C4H2 PF10146.9 GAN06111.1 - 1.3 9.3 15.1 1.3 9.2 13.7 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein V_ATPase_I PF01496.19 GAN06111.1 - 1.5 6.6 9.6 1.9 6.3 9.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PEP-utilisers_N PF05524.13 GAN06111.1 - 1.6 8.9 9.9 0.32 11.2 3.5 2.6 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal DUF848 PF05852.11 GAN06111.1 - 1.9 8.6 13.9 0.22 11.6 8.0 2.3 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Prominin PF05478.11 GAN06111.1 - 2.3 6.0 9.1 3.6 5.4 9.1 1.3 1 0 0 1 1 1 0 Prominin Ribosomal_L27A PF00828.19 GAN06111.1 - 4.5 8.0 6.1 3.6 8.3 1.2 2.3 1 1 1 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Prefoldin PF02996.17 GAN06111.1 - 5.7 6.9 18.4 8.7 6.3 0.7 4.0 2 1 3 5 5 5 0 Prefoldin subunit DUF1664 PF07889.12 GAN06111.1 - 6 6.9 16.7 16 5.6 6.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1319 PF07028.11 GAN06111.1 - 7.5 6.8 11.0 0.55 10.5 2.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) Epimerase PF01370.21 GAN06112.1 - 8.6e-52 176.0 0.0 1.5e-51 175.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAN06112.1 - 2.6e-15 56.7 0.2 6.2e-15 55.4 0.2 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAN06112.1 - 5.6e-07 29.0 0.2 3.7e-05 23.0 0.0 2.8 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAN06112.1 - 0.00035 19.7 0.0 0.0008 18.6 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain AnfO_nitrog PF09582.10 GAN06112.1 - 0.023 14.0 0.3 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF3246 PF11596.8 GAN06114.1 - 0.00026 20.5 3.8 0.00026 20.5 3.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3246) DUF3164 PF11363.8 GAN06114.1 - 0.022 14.4 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) ATP-synt_C PF00137.21 GAN06115.1 - 8.9e-35 118.8 34.5 2.2e-23 82.4 14.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 GAN06115.1 - 1 9.1 5.5 2.9 7.6 1.2 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain UCH PF00443.29 GAN06116.1 - 1.2e-65 221.6 0.0 2e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN06116.1 - 2.5e-21 76.6 0.0 2.2e-19 70.2 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 GAN06116.1 - 4.4e-13 49.4 1.0 8.9e-13 48.4 1.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 GAN06116.1 - 0.00017 22.1 0.0 0.00041 20.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 GAN06116.1 - 0.055 13.2 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RanBP PF00641.18 GAN06116.1 - 3.9 6.9 5.3 5.7 6.4 1.1 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others HhH-GPD PF00730.25 GAN06117.1 - 2.4e-13 50.4 0.0 6.8e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CorC_HlyC PF03471.17 GAN06117.1 - 0.07 13.1 2.5 0.67 10.0 0.0 2.8 3 0 0 3 3 3 0 Transporter associated domain pP_pnuc_2 PF18166.1 GAN06117.1 - 0.089 12.9 2.2 0.17 12.0 0.6 2.1 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease Syja_N PF02383.18 GAN06118.1 - 1.7e-90 303.6 4.7 3.7e-90 302.5 4.7 1.6 1 1 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 GAN06118.1 - 1.1e-33 115.3 0.1 2.7e-33 114.1 0.1 1.6 1 0 0 1 1 1 1 Inositol phosphatase Metallophos_2 PF12850.7 GAN06119.1 - 4.4e-19 69.3 0.0 5e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Abhydrolase_1 PF00561.20 GAN06119.1 - 6.8e-16 58.7 0.0 6.7e-14 52.1 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN06119.1 - 5.1e-14 52.1 0.0 2.4e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN06119.1 - 4.6e-08 33.9 0.0 6.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.28 GAN06119.1 - 0.00026 21.6 0.3 0.14 12.7 0.2 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Esterase PF00756.20 GAN06119.1 - 0.00044 20.0 0.0 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 GAN06119.1 - 0.059 12.8 0.0 8.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAN06119.1 - 0.1 12.2 0.1 13 5.2 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 GAN06119.1 - 0.12 11.9 0.0 9.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase zf-HC5HC2H_2 PF13832.6 GAN06120.1 - 2.7e-09 37.2 1.1 2.7e-09 37.2 1.1 3.9 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD PF00628.29 GAN06120.1 - 4.2e-09 36.2 37.6 4e-05 23.4 4.5 4.8 5 1 0 5 5 5 3 PHD-finger zf-HC5HC2H PF13771.6 GAN06120.1 - 0.00054 20.2 0.4 0.00054 20.2 0.4 4.9 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD_2 PF13831.6 GAN06120.1 - 0.0049 16.4 4.2 0.0049 16.4 4.2 4.3 3 0 0 3 3 3 2 PHD-finger FANCL_C PF11793.8 GAN06120.1 - 0.0064 16.6 1.1 0.0064 16.6 1.1 3.9 4 0 0 4 4 4 1 FANCL C-terminal domain PBP1_TM PF14812.6 GAN06121.1 - 0.096 13.1 5.8 0.14 12.5 5.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyclin_N PF00134.23 GAN06122.1 - 1.2e-09 38.0 0.2 1.7e-09 37.5 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN06122.1 - 8.9e-06 26.2 0.2 1.2e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin Cys_rich_KTR PF14205.6 GAN06122.1 - 0.17 11.7 0.5 0.29 11.0 0.5 1.4 1 0 0 1 1 1 0 Cysteine-rich KTR Sugar_tr PF00083.24 GAN06123.1 - 2.5e-95 320.0 16.1 4.4e-95 319.2 16.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN06123.1 - 3.8e-22 78.7 21.2 6.8e-22 77.9 21.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3084 PF11283.8 GAN06123.1 - 0.63 10.1 4.4 0.43 10.6 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3084) PH_9 PF15410.6 GAN06124.1 - 1.2e-12 48.2 0.0 3.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAN06124.1 - 3.4e-05 24.3 0.0 9.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 PH domain 17kDa_Anti_2 PF16998.5 GAN06124.1 - 0.22 11.5 0.8 1.4 8.9 0.2 2.4 2 1 1 3 3 3 0 17 kDa outer membrane surface antigen Arrestin_N PF00339.29 GAN06125.1 - 4.6e-08 33.2 0.0 2.1e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN06125.1 - 0.02 15.3 0.5 0.05 14.1 0.5 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain GDP_Man_Dehyd PF16363.5 GAN06126.1 - 5.9e-74 249.4 0.0 7e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAN06126.1 - 5.7e-55 186.4 0.0 7.1e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN06126.1 - 6.1e-22 77.9 0.1 8.5e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAN06126.1 - 1.1e-20 73.9 0.1 6.7e-15 54.9 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 GAN06126.1 - 2.3e-19 69.6 0.0 5.6e-18 65.1 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAN06126.1 - 1.4e-16 60.4 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAN06126.1 - 0.0004 20.3 0.0 0.00079 19.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RibD_C PF01872.17 GAN06126.1 - 0.19 11.5 0.0 0.38 10.6 0.0 1.5 2 0 0 2 2 2 0 RibD C-terminal domain NAT PF04768.13 GAN06127.1 - 1.5e-44 151.7 0.1 3.1e-44 150.6 0.1 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AAA PF00004.29 GAN06127.1 - 9.6e-15 55.2 0.0 2.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sel1 PF08238.12 GAN06127.1 - 1.7e-11 44.4 25.1 3e-07 30.9 0.5 7.9 8 0 0 8 8 8 3 Sel1 repeat AAA_lid_10 PF17872.1 GAN06127.1 - 1.1e-09 38.4 0.3 4.9e-09 36.2 0.3 2.2 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 GAN06127.1 - 1.7e-09 38.1 0.1 1.1e-08 35.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAN06127.1 - 2.2e-08 34.7 0.0 1.1e-07 32.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 GAN06127.1 - 9.1e-05 22.8 0.0 0.0005 20.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 GAN06127.1 - 0.00035 19.9 0.3 0.0016 17.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Cdc6_C PF09079.11 GAN06127.1 - 0.00065 19.6 0.1 0.0044 17.0 0.0 2.6 3 0 0 3 3 3 1 CDC6, C terminal winged helix domain NACHT PF05729.12 GAN06127.1 - 0.0057 16.6 0.2 4.6 7.1 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 GAN06127.1 - 0.0064 16.3 0.0 0.0064 16.3 0.0 3.7 3 1 1 4 4 2 1 AAA domain ATPase_2 PF01637.18 GAN06127.1 - 0.022 14.6 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 GAN06127.1 - 0.039 13.2 0.0 0.3 10.3 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.6 GAN06127.1 - 0.092 12.8 0.0 0.46 10.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain Peptidase_C12 PF01088.21 GAN06128.1 - 6.6e-71 238.4 0.1 1.6e-70 237.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 GAN06128.1 - 8.5e-17 60.8 4.4 1.9e-16 59.6 4.4 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DUF629 PF04780.12 GAN06128.1 - 0.0063 15.1 2.0 0.008 14.8 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) Pox_Ag35 PF03286.14 GAN06129.1 - 0.05 13.4 6.6 0.059 13.2 6.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOZZLE PF08744.10 GAN06129.1 - 0.091 12.2 0.5 0.092 12.2 0.5 1.1 1 0 0 1 1 1 0 Plant transcription factor NOZZLE TSGP1 PF07771.11 GAN06129.1 - 0.42 10.8 8.1 0.49 10.6 8.1 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF3464 PF11947.8 GAN06129.1 - 6.3 6.5 7.0 7.7 6.3 7.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 HAT_KAT11 PF08214.11 GAN06131.1 - 2.4e-40 138.9 0.7 3.4e-40 138.4 0.7 1.1 1 0 0 1 1 1 1 Histone acetylation protein Sel1 PF08238.12 GAN06132.1 - 4.6e-05 23.9 1.9 2.5 8.9 0.0 3.9 4 0 0 4 4 4 3 Sel1 repeat Epimerase PF01370.21 GAN06133.1 - 1e-23 84.0 0.1 2e-23 83.1 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAN06133.1 - 1.3e-11 44.5 0.1 2.5e-11 43.6 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAN06133.1 - 5.9e-11 42.0 0.0 8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAN06133.1 - 1.1e-10 41.0 0.1 1.5e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAN06133.1 - 3.1e-06 27.2 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAN06133.1 - 7.4e-05 23.0 0.0 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 GAN06133.1 - 0.0016 17.6 0.6 0.0088 15.2 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAN06133.1 - 0.045 12.9 0.2 0.43 9.7 0.2 2.3 1 1 0 1 1 1 0 Male sterility protein Tube PF17212.3 GAN06133.1 - 0.079 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Tail tubular protein Chitin_synth_2 PF03142.15 GAN06134.1 - 1e-277 922.0 0.3 1.4e-277 921.5 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAN06134.1 - 1.6e-13 51.1 0.0 1.6e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN06134.1 - 2e-13 50.7 2.5 5.7e-13 49.2 2.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GAN06134.1 - 0.0096 15.4 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAN06134.1 - 0.017 14.9 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 E1-E2_ATPase PF00122.20 GAN06135.1 - 5e-46 156.5 2.7 5e-46 156.5 2.7 3.6 5 0 0 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 GAN06135.1 - 5.2e-21 75.9 0.1 1.2e-20 74.7 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN06135.1 - 1.1e-12 47.4 0.0 3.4e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN06135.1 - 0.034 13.9 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Perilipin PF03036.16 GAN06136.1 - 3.4e-12 46.1 9.0 2.5e-09 36.7 9.0 2.3 1 1 0 1 1 1 1 Perilipin family Apolipoprotein PF01442.18 GAN06136.1 - 0.00063 19.7 1.9 0.0052 16.7 1.2 2.5 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain ETF_QO PF05187.13 GAN06136.1 - 0.0025 17.9 0.1 0.81 9.9 0.0 2.6 2 0 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S ASL_C PF08328.11 GAN06136.1 - 0.0087 16.1 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Phasin PF05597.11 GAN06136.1 - 0.031 14.3 2.1 5.8 6.9 0.0 4.0 3 2 2 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) S36_mt PF10937.8 GAN06136.1 - 0.18 13.4 0.6 4.4 8.9 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein S36, mitochondrial DUF5344 PF17279.2 GAN06136.1 - 0.18 12.4 7.0 1.5 9.4 0.3 4.1 4 1 1 5 5 5 0 Family of unknown function (DUF5344) FlxA PF14282.6 GAN06136.1 - 2.4 8.2 12.5 0.064 13.3 1.7 3.3 2 2 1 3 3 3 0 FlxA-like protein DUF3767 PF12597.8 GAN06137.1 - 4e-30 103.6 0.0 5.1e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) ATP-synt PF00231.19 GAN06138.1 - 1.7e-75 254.3 7.0 2e-75 254.1 7.0 1.0 1 0 0 1 1 1 1 ATP synthase ACT_4 PF13291.6 GAN06138.1 - 0.003 18.1 0.4 0.0082 16.7 0.4 1.7 1 0 0 1 1 1 1 ACT domain AHD PF17793.1 GAN06138.1 - 0.88 9.4 2.8 1.5 8.6 1.1 2.2 2 0 0 2 2 2 0 ANC1 homology domain (AHD) zf-H2C2_2 PF13465.6 GAN06139.1 - 1.5e-07 31.5 19.7 1.2e-05 25.5 2.9 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN06139.1 - 5.9e-05 23.6 25.0 0.0045 17.7 1.2 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN06139.1 - 0.00012 22.3 1.2 0.00012 22.3 1.2 5.6 6 0 0 6 6 6 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAN06139.1 - 0.017 15.7 1.0 0.017 15.7 1.0 5.2 4 1 1 5 5 5 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 GAN06139.1 - 2.1 8.5 5.0 29 4.8 0.1 3.2 3 1 0 3 3 3 0 Aberrant zinc-finger Zap1_zf2 PF18217.1 GAN06139.1 - 2.8 8.0 6.4 1.3 9.0 0.4 2.9 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf-C2H2_6 PF13912.6 GAN06139.1 - 4.4 7.4 12.8 0.61 10.2 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-TRAF PF02176.18 GAN06139.1 - 5.2 7.8 10.1 2.1 9.1 3.1 3.3 2 1 1 3 3 3 0 TRAF-type zinc finger Aminotran_5 PF00266.19 GAN06141.1 - 2.2e-94 316.5 0.0 2.6e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAN06141.1 - 3.3e-09 36.5 0.0 4.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAN06141.1 - 1.6e-05 24.4 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 GAN06141.1 - 0.0004 19.2 0.0 0.00066 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 GAN06141.1 - 0.0076 14.8 0.0 0.013 14.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Tctex-1 PF03645.13 GAN06141.1 - 0.024 14.9 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Tctex-1 family DUF3217 PF11506.8 GAN06141.1 - 0.04 13.9 0.3 0.094 12.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3217) 4_1_CTD PF05902.13 GAN06141.1 - 0.043 13.9 0.2 0.11 12.6 0.2 1.7 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) CsbD PF05532.12 GAN06142.1 - 8.9e-15 54.3 17.2 1.5e-09 37.6 3.8 2.1 1 1 1 2 2 2 2 CsbD-like Mito_carr PF00153.27 GAN06143.1 - 1.5e-66 220.4 2.0 1.4e-21 76.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PSI_PsaE PF02427.17 GAN06143.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE RNA12 PF10443.9 GAN06144.1 - 5.3e-111 371.5 6.2 4.6e-72 243.1 0.8 2.1 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 GAN06144.1 - 1.1e-09 38.6 0.4 0.00055 19.9 0.0 2.8 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea RRM_1 PF00076.22 GAN06144.1 - 2.3e-05 24.1 0.0 5.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 GAN06144.1 - 0.00036 20.9 0.2 0.0011 19.4 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 GAN06144.1 - 0.00038 20.2 0.4 0.00092 19.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain DUF2487 PF10673.9 GAN06144.1 - 0.0034 17.4 0.0 0.0093 16.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_22 PF13401.6 GAN06144.1 - 0.014 15.7 0.2 0.4 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAN06144.1 - 0.025 13.7 0.0 0.054 12.7 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 GAN06144.1 - 0.041 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 GAN06144.1 - 0.041 13.0 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 GAN06144.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 GAN06144.1 - 0.12 12.4 0.0 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sel1 PF08238.12 GAN06145.1 - 1.1e-36 124.4 16.5 2.4e-06 28.0 0.2 7.5 8 0 0 8 8 8 7 Sel1 repeat ANAPC3 PF12895.7 GAN06145.1 - 3 8.1 9.5 3.3 8.0 0.5 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 GAN06146.1 - 8.9e-19 67.5 15.0 2.7e-09 37.4 0.1 7.5 8 0 0 8 8 8 3 Sel1 repeat zf-MYND PF01753.18 GAN06146.1 - 1.1e-08 35.0 14.7 2.2e-08 34.1 14.7 1.5 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.6 GAN06146.1 - 0.0011 19.2 0.4 0.009 16.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat CODH_A_N PF18537.1 GAN06146.1 - 0.017 15.1 0.3 0.051 13.6 0.1 2.0 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Antimicrobial25 PF16839.5 GAN06146.1 - 0.11 12.6 4.3 0.25 11.5 4.3 1.6 1 0 0 1 1 1 0 Nematode antimicrobial peptide DUF512 PF04459.12 GAN06146.1 - 0.15 11.3 0.1 0.31 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF512) TPR_6 PF13174.6 GAN06146.1 - 0.21 12.3 6.9 0.7 10.7 0.2 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAN06146.1 - 0.65 10.2 9.9 14 5.9 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN06146.1 - 2.4 8.6 20.5 1.2 9.5 1.6 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat zf-Tim10_DDP PF02953.15 GAN06148.1 - 1.4e-21 75.9 1.6 1.8e-21 75.5 1.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps54 PF07928.12 GAN06148.1 - 0.024 15.1 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Vps54-like protein Methyltransf_25 PF13649.6 GAN06149.1 - 3.7e-06 27.5 0.0 1.2e-05 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN06149.1 - 3.9e-06 27.4 0.0 9.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN06149.1 - 0.0015 18.4 0.0 0.0045 16.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAN06149.1 - 0.0084 16.0 0.0 0.03 14.1 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 GAN06149.1 - 0.02 14.3 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase MA3 PF02847.17 GAN06149.1 - 0.071 13.1 0.7 0.59 10.1 0.1 2.3 2 0 0 2 2 2 0 MA3 domain Methyltransf_12 PF08242.12 GAN06149.1 - 0.16 12.7 0.3 0.79 10.5 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain PRELI PF04707.14 GAN06150.1 - 5.2e-49 166.1 0.5 6.2e-49 165.8 0.5 1.0 1 0 0 1 1 1 1 PRELI-like family PhaP_Bmeg PF09602.10 GAN06150.1 - 0.081 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) zf-MIZ PF02891.20 GAN06151.1 - 4.5e-12 45.5 2.5 8.9e-12 44.6 2.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger M20_dimer PF07687.14 GAN06151.1 - 7.3e-10 38.7 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PPR PF01535.20 GAN06152.1 - 9.7e-09 34.9 9.2 0.0025 18.0 0.0 7.7 10 0 0 10 10 10 1 PPR repeat PPR_2 PF13041.6 GAN06152.1 - 6.7e-08 32.6 6.5 2.5 8.4 0.1 6.4 6 0 0 6 6 6 4 PPR repeat family PPR_3 PF13812.6 GAN06152.1 - 0.00047 20.2 1.4 0.63 10.2 0.0 4.8 5 1 0 5 5 5 1 Pentatricopeptide repeat domain VWA_2 PF13519.6 GAN06152.1 - 0.09 13.4 1.5 0.48 11.1 0.0 2.9 4 0 0 4 4 4 0 von Willebrand factor type A domain PPR_1 PF12854.7 GAN06152.1 - 0.94 9.2 2.5 36 4.2 0.1 3.7 4 0 0 4 4 4 0 PPR repeat Sec7 PF01369.20 GAN06153.1 - 1.7e-71 239.7 0.1 7.5e-71 237.6 0.1 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAN06153.1 - 2.7e-41 141.1 1.0 2.7e-41 141.1 1.0 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAN06153.1 - 8e-34 115.4 11.4 3.5e-31 106.9 0.1 6.4 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAN06153.1 - 2.5e-21 76.1 1.7 2.8e-20 72.7 2.3 2.5 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 HK97-gp10_like PF04883.12 GAN06153.1 - 0.2 12.6 1.3 1.2 10.2 0.2 2.8 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF1539 PF07560.11 GAN06153.1 - 0.6 10.2 5.0 28 4.8 0.0 4.8 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1539) Zip PF02535.22 GAN06153.1 - 4.3 6.5 10.1 9.8 5.3 10.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Zn_clus PF00172.18 GAN06154.1 - 0.00018 21.6 11.4 0.0005 20.1 11.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.13 GAN06154.1 - 3 8.5 8.2 1.3 9.7 3.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sel1 PF08238.12 GAN06155.1 - 2.4e-122 396.6 55.7 5.2e-11 42.8 0.0 15.5 16 0 0 16 16 16 15 Sel1 repeat TPR_6 PF13174.6 GAN06155.1 - 3.6e-06 27.2 15.6 1.3 9.8 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06155.1 - 2.6 8.6 11.7 2.2 8.9 0.1 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 GAN06156.1 - 1.5e-76 256.6 0.1 3.2e-76 255.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAN06156.1 - 8.3e-41 139.0 1.4 7.3e-40 135.9 0.3 3.0 2 1 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN06156.1 - 2.5e-36 124.0 0.0 7.6e-36 122.5 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAN06156.1 - 6.3e-17 61.2 1.2 2e-16 59.5 0.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAN06156.1 - 7.2e-10 38.7 0.1 1.6e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 GAN06156.1 - 1.1e-07 31.6 0.2 0.0003 20.5 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 GAN06156.1 - 8.3e-06 25.5 0.1 1.8e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 GAN06156.1 - 5.7e-05 23.8 1.1 0.33 11.7 0.1 3.5 4 0 0 4 4 4 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 GAN06156.1 - 9.6e-05 22.5 0.1 0.0002 21.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAN06156.1 - 0.00063 19.4 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 GAN06156.1 - 0.0092 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 GAN06156.1 - 0.037 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp BRCT_2 PF16589.5 GAN06157.1 - 1.9e-09 37.8 0.4 0.0032 17.8 0.2 3.8 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAN06157.1 - 2.4e-08 34.2 0.9 5.3e-06 26.7 0.0 3.5 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 GAN06157.1 - 0.00073 19.6 0.5 1.1 9.4 0.0 3.6 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 GAN06157.1 - 0.014 15.3 0.2 0.52 10.2 0.0 3.2 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GAN06157.1 - 0.024 14.6 1.7 11 6.1 0.1 3.8 3 1 1 4 4 4 0 twin BRCT domain MFS_1 PF07690.16 GAN06160.1 - 2.3e-19 69.5 56.8 1.1e-15 57.5 34.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily BCHF PF07284.11 GAN06160.1 - 0.0049 16.9 3.7 0.11 12.5 0.4 2.7 2 0 0 2 2 2 2 2-vinyl bacteriochlorophyllide hydratase (BCHF) GerPE PF10970.8 GAN06161.1 - 0.025 14.8 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Spore germination protein GerPE RVT_1 PF00078.27 GAN06162.1 - 7.5e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Coatomer_WDAD PF04053.14 GAN06163.1 - 3e-169 563.8 0.0 8.5e-168 559.0 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAN06163.1 - 1.5e-40 136.4 2.5 1.7e-08 35.0 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06163.1 - 2.5e-12 46.9 0.1 0.23 11.8 0.0 7.6 3 2 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAN06163.1 - 0.0002 21.4 0.0 8.6 6.4 0.0 4.7 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.20 GAN06163.1 - 0.032 14.1 0.0 9.1 6.2 0.0 2.4 1 1 1 2 2 2 0 Region in Clathrin and VPS BCDHK_Adom3 PF10436.9 GAN06164.1 - 5.4e-08 32.8 0.2 1.2e-07 31.8 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Toprim_3 PF13362.6 GAN06164.1 - 0.061 13.7 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Toprim domain bZIP_1 PF00170.21 GAN06165.1 - 1.2e-12 47.7 9.8 1.2e-12 47.7 9.8 1.5 2 0 0 2 2 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN06165.1 - 9.8e-08 32.0 10.2 1.8e-07 31.1 10.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 GAN06165.1 - 0.00019 21.8 0.6 0.00019 21.8 0.6 3.0 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain HALZ PF02183.18 GAN06165.1 - 0.0035 17.5 3.1 0.0051 17.0 1.5 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_Maf PF03131.17 GAN06165.1 - 0.0039 17.7 4.9 0.0039 17.7 4.9 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor JIP_LZII PF16471.5 GAN06165.1 - 0.0048 17.0 0.5 0.0093 16.1 0.5 1.4 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II ASD2 PF08687.11 GAN06165.1 - 0.0052 16.4 3.7 0.007 16.0 3.7 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 DUF2576 PF10845.8 GAN06165.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) YabA PF06156.13 GAN06165.1 - 0.073 13.7 3.5 0.1 13.2 3.0 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Ant_C PF05586.11 GAN06165.1 - 0.086 13.4 0.7 0.23 12.1 0.7 1.7 1 0 0 1 1 1 0 Anthrax receptor C-terminus region ZapB PF06005.12 GAN06165.1 - 0.17 12.4 4.8 0.072 13.5 2.0 1.8 1 1 1 2 2 2 0 Cell division protein ZapB Phlebovirus_NSM PF07246.11 GAN06165.1 - 0.85 8.9 5.2 1.7 7.9 5.2 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M 2-oxoacid_dh PF00198.23 GAN06167.1 - 1.4e-81 273.4 0.4 2.1e-81 272.8 0.4 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAN06167.1 - 2.5e-17 62.5 1.8 5.5e-17 61.4 1.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 GAN06167.1 - 6.5e-05 22.8 0.5 0.00015 21.6 0.5 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 GAN06167.1 - 0.0018 19.0 0.5 0.76 10.5 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 GAN06167.1 - 0.0038 17.0 1.4 0.27 11.1 0.2 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like DUF3614 PF12267.8 GAN06167.1 - 0.0053 17.3 1.1 0.28 11.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3614) RnfC_N PF13375.6 GAN06167.1 - 0.023 14.6 0.2 0.065 13.2 0.2 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain FAM76 PF16046.5 GAN06167.1 - 1.7 7.9 4.6 17 4.7 2.5 2.1 2 0 0 2 2 2 0 FAM76 protein 4HBT PF03061.22 GAN06168.1 - 1.8e-08 34.6 0.0 4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily NAPRTase PF04095.16 GAN06169.1 - 2.9e-66 223.5 1.8 4.3e-66 223.0 1.8 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 GAN06169.1 - 8.4e-35 119.9 1.2 1.5e-34 119.0 1.2 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Egg_lysin PF01303.17 GAN06169.1 - 0.14 12.4 1.9 0.15 12.2 0.5 1.8 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) Zds_C PF08632.10 GAN06170.1 - 1e-22 79.6 0.4 2.1e-22 78.6 0.4 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Septin PF00735.18 GAN06171.1 - 7.7e-115 383.0 0.7 9.6e-115 382.7 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN06171.1 - 3.5e-09 36.7 0.1 1.2e-08 35.0 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN06171.1 - 6.9e-08 32.6 0.5 1.1e-06 28.7 0.3 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 GAN06171.1 - 1.8e-06 27.5 0.0 3.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 GAN06171.1 - 7.4e-06 25.6 0.2 0.0003 20.4 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN06171.1 - 2.2e-05 24.0 0.2 0.005 16.2 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 GAN06171.1 - 9.2e-05 21.7 0.1 0.00018 20.8 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAN06171.1 - 0.00032 21.1 0.3 0.0012 19.3 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 GAN06171.1 - 0.00064 19.8 3.9 0.43 10.6 0.8 2.8 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.27 GAN06171.1 - 0.001 19.6 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Ras PF00071.22 GAN06171.1 - 0.0022 17.6 0.1 0.0078 15.8 0.0 2.0 2 1 0 2 2 2 1 Ras family Roc PF08477.13 GAN06171.1 - 0.0024 18.1 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 GAN06171.1 - 0.0045 16.5 0.5 0.024 14.1 0.3 2.2 1 1 1 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 GAN06171.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 GAN06171.1 - 0.0072 16.6 0.1 0.015 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 GAN06171.1 - 0.012 14.8 1.7 0.17 11.0 0.5 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 GAN06171.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 GAN06171.1 - 0.022 14.8 0.2 0.077 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF1542 PF07564.11 GAN06171.1 - 0.025 14.7 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF815 PF05673.13 GAN06171.1 - 0.031 13.4 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 GAN06171.1 - 0.052 13.2 0.1 0.092 12.4 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.13 GAN06171.1 - 0.064 12.3 0.3 0.15 11.1 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 GAN06171.1 - 0.13 12.0 0.3 0.45 10.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAN06171.1 - 0.15 12.2 0.4 0.84 9.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.6 GAN06172.1 - 4e-21 74.4 31.2 2.8e-07 30.7 1.1 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 GAN06172.1 - 3.1e-20 71.4 32.9 1.9e-06 28.0 0.7 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN06172.1 - 1.2e-10 41.3 30.3 0.0082 16.9 1.8 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN06172.1 - 0.0012 19.0 14.6 0.13 12.6 0.1 5.2 5 0 0 5 5 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN06172.1 - 0.0064 16.8 5.1 0.69 10.4 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type SUIM_assoc PF16619.5 GAN06172.1 - 0.016 15.2 4.4 0.016 15.2 4.4 3.0 3 0 0 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 NPR1_interact PF15699.5 GAN06172.1 - 0.12 13.0 7.8 0.14 12.8 0.5 2.3 2 0 0 2 2 2 0 NPR1 interacting zf-C2H2_6 PF13912.6 GAN06172.1 - 0.14 12.2 16.5 2.3 8.3 0.2 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Roughex PF06020.11 GAN06172.1 - 0.3 10.1 6.9 1.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Drosophila roughex protein AIF_C PF14721.6 GAN06172.1 - 0.49 10.7 3.4 3.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 GAN06172.1 - 0.5 9.1 8.2 0.64 8.7 8.2 1.2 1 0 0 1 1 1 0 Presenilin zf-C2H2_aberr PF17017.5 GAN06172.1 - 1.1 9.3 7.5 3.6 7.7 0.6 3.1 2 2 1 3 3 3 0 Aberrant zinc-finger Macoilin PF09726.9 GAN06172.1 - 1.3 7.5 10.8 1.7 7.1 10.8 1.1 1 0 0 1 1 1 0 Macoilin family M_domain PF12938.7 GAN06172.1 - 2.2 8.0 36.3 1 9.1 12.8 2.2 2 0 0 2 2 2 0 M domain of GW182 PLATZ PF04640.14 GAN06172.1 - 2.5 8.8 14.7 0.84 10.3 7.2 2.6 2 0 0 2 2 2 0 PLATZ transcription factor DUF4834 PF16118.5 GAN06172.1 - 2.9 8.9 13.4 9.7 7.2 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peroxin-3 PF04882.12 GAN06172.1 - 3.6 6.5 15.4 5.4 5.9 15.4 1.2 1 0 0 1 1 1 0 Peroxin-3 Androgen_recep PF02166.16 GAN06172.1 - 3.6 6.3 30.4 2.7 6.7 8.8 2.1 2 0 0 2 2 2 0 Androgen receptor HbrB PF08539.11 GAN06172.1 - 6.8 6.7 7.2 33 4.4 7.2 2.0 1 1 0 1 1 1 0 HbrB-like SR-25 PF10500.9 GAN06172.1 - 7.2 6.2 18.2 16 5.0 15.6 2.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 GAN06172.1 - 7.5 5.4 39.0 0.27 10.1 12.8 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Sox_N PF12444.8 GAN06172.1 - 9.8 7.4 13.1 4.2 8.6 8.5 2.4 2 0 0 2 2 2 0 Sox developmental protein N terminal UVR PF02151.19 GAN06173.1 - 0.077 12.8 0.1 0.077 12.8 0.1 5.7 7 0 0 7 7 7 0 UvrB/uvrC motif OAD_gamma PF04277.13 GAN06174.1 - 0.00057 20.4 0.7 0.0013 19.3 0.7 1.5 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF4381 PF14316.6 GAN06174.1 - 0.00082 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) TMEM154 PF15102.6 GAN06174.1 - 0.0092 15.9 0.4 0.022 14.6 0.4 1.8 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 GAN06174.1 - 0.012 16.5 0.8 0.023 15.6 0.8 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 GAN06174.1 - 0.013 16.5 2.4 0.067 14.2 2.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Phage_holin_3_6 PF07332.11 GAN06174.1 - 0.018 15.1 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Shisa PF13908.6 GAN06174.1 - 0.02 15.1 1.1 0.032 14.5 0.3 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator tRNA_anti-like PF12869.7 GAN06174.1 - 0.026 14.1 0.6 0.051 13.2 0.6 1.4 1 0 0 1 1 1 0 tRNA_anti-like DUF2140 PF09911.9 GAN06174.1 - 0.026 14.1 0.2 0.047 13.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) UPF0242 PF06785.11 GAN06174.1 - 0.035 14.2 0.2 0.056 13.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sigma_reg_N PF13800.6 GAN06174.1 - 0.037 14.3 0.1 0.074 13.3 0.1 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal O-antigen_lig PF13425.6 GAN06174.1 - 0.038 12.8 0.6 0.047 12.5 0.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Saf_2TM PF18303.1 GAN06174.1 - 0.043 13.4 0.6 0.083 12.5 0.6 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Wzy_C PF04932.15 GAN06174.1 - 0.047 13.3 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase FixS PF03597.15 GAN06174.1 - 0.055 13.2 1.6 0.09 12.5 1.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type OATP PF03137.20 GAN06174.1 - 0.06 11.6 0.1 0.07 11.4 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SID-1_RNA_chan PF13965.6 GAN06174.1 - 0.062 11.7 1.0 0.072 11.5 1.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2681 PF10883.8 GAN06174.1 - 0.071 13.5 0.1 0.071 13.5 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) DUF4448 PF14610.6 GAN06174.1 - 0.084 12.6 0.5 0.18 11.5 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) SIT PF15330.6 GAN06174.1 - 0.092 13.2 0.1 0.092 13.2 0.1 1.6 2 0 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT ASFV_J13L PF05568.11 GAN06174.1 - 0.11 12.3 4.1 0.2 11.4 4.0 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein MFS_1 PF07690.16 GAN06174.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily OSTbeta PF15048.6 GAN06174.1 - 0.17 12.0 1.5 0.35 11.0 1.5 1.6 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Vpu PF00558.19 GAN06174.1 - 0.26 11.1 4.3 0.6 9.9 4.3 1.5 1 0 0 1 1 1 0 Vpu protein FeoB_associated PF12669.7 GAN06174.1 - 0.66 10.4 5.8 1.2 9.6 5.8 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4446 PF14584.6 GAN06174.1 - 2.2 8.2 4.7 1 9.3 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Ribosomal_L15e PF00827.17 GAN06175.1 - 6.3e-67 225.0 6.3 1.1e-66 224.3 6.3 1.3 1 0 0 1 1 1 1 Ribosomal L15 TruB_N PF01509.18 GAN06175.1 - 9.4e-44 149.4 0.0 1.7e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) F-box-like PF12937.7 GAN06175.1 - 2.2e-09 37.1 3.1 2.2e-09 37.1 3.1 2.9 3 0 0 3 3 3 1 F-box-like TruB_C_2 PF16198.5 GAN06175.1 - 6.1e-07 29.5 0.1 2.4e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain F-box PF00646.33 GAN06175.1 - 6.7e-06 25.8 1.9 0.001 18.9 0.1 3.8 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 GAN06175.1 - 0.00019 21.2 17.0 13 6.2 0.0 9.3 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.7 GAN06175.1 - 0.0006 20.2 17.1 11 6.6 0.0 7.8 5 2 6 11 11 11 1 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 GAN06175.1 - 0.075 12.7 0.8 4.1 7.1 0.0 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1699) DUF5615 PF18480.1 GAN06175.1 - 0.15 11.8 0.0 10 6.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5615) TolA_bind_tri PF16331.5 GAN06176.1 - 0.0011 19.0 7.9 0.0016 18.5 7.9 1.3 1 0 0 1 1 1 1 TolA binding protein trimerisation Frigida PF07899.11 GAN06176.1 - 0.0033 16.7 2.4 0.0034 16.7 2.4 1.1 1 0 0 1 1 1 1 Frigida-like protein DUF4795 PF16043.5 GAN06176.1 - 0.0046 16.6 3.0 0.005 16.5 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) ZapB PF06005.12 GAN06176.1 - 0.0063 16.9 10.0 0.019 15.4 10.0 1.7 1 1 0 1 1 1 1 Cell division protein ZapB TMF_DNA_bd PF12329.8 GAN06176.1 - 0.0095 15.9 9.5 0.01 15.8 5.0 2.1 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Tox-URI2 PF15653.6 GAN06176.1 - 0.018 15.3 0.3 0.023 15.0 0.3 1.3 1 0 0 1 1 1 0 URI fold toxin 2 Tho2 PF11262.8 GAN06176.1 - 0.019 14.2 4.7 0.021 14.1 4.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 bZIP_2 PF07716.15 GAN06176.1 - 0.026 14.6 7.6 0.069 13.2 2.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper COG6 PF06419.11 GAN06176.1 - 0.035 12.3 4.7 0.04 12.1 4.7 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 TraF_2 PF13729.6 GAN06176.1 - 0.043 13.2 0.3 0.05 13.0 0.3 1.0 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Synaptobrevin PF00957.21 GAN06176.1 - 0.055 13.3 3.4 0.07 12.9 3.4 1.2 1 0 0 1 1 1 0 Synaptobrevin Cep57_MT_bd PF06657.13 GAN06176.1 - 0.056 13.9 6.7 0.077 13.5 6.7 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 GAN06176.1 - 0.072 12.9 11.3 0.13 12.0 5.1 2.1 1 1 1 2 2 2 0 Septum formation initiator Prominin PF05478.11 GAN06176.1 - 0.16 9.9 4.1 0.16 9.9 4.1 1.0 1 0 0 1 1 1 0 Prominin GIT_CC PF16559.5 GAN06176.1 - 0.39 10.6 6.7 7.3 6.5 6.6 2.3 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1515 PF07439.11 GAN06176.1 - 0.49 10.5 3.4 7.2 6.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4140 PF13600.6 GAN06176.1 - 0.59 10.6 4.8 2.3 8.7 4.8 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 GAN06176.1 - 1.7 9.3 8.9 8.6 7.1 0.9 2.1 1 1 1 2 2 2 0 SlyX Sulfotransfer_4 PF17784.1 GAN06177.1 - 5.8e-59 199.5 0.0 7e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAN06177.1 - 0.049 14.0 0.4 0.66 10.3 0.0 2.2 1 1 1 2 2 2 0 Sulfotransferase family Pro-NT_NN PF07421.11 GAN06177.1 - 0.099 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor PXA PF02194.15 GAN06178.1 - 0.039 13.9 9.0 0.028 14.4 4.5 2.7 2 1 0 2 2 2 0 PXA domain ARGLU PF15346.6 GAN06178.1 - 0.076 12.9 17.7 0.054 13.4 14.1 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Methyltransf_29 PF03141.16 GAN06178.1 - 1.7 7.1 8.4 0.24 9.9 0.6 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4112 PF13430.6 GAN06179.1 - 1e-35 122.2 2.0 1.3e-35 121.8 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) RhoGAP PF00620.27 GAN06180.1 - 2.1e-49 167.2 0.7 8.2e-49 165.3 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 GAN06180.1 - 1.1e-13 51.2 33.1 3.6e-08 33.5 8.8 3.1 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 GAN06180.1 - 2e-08 34.0 1.5 2e-08 34.0 1.5 4.3 2 1 2 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) NPV_P10 PF05531.12 GAN06180.1 - 0.26 11.8 4.0 0.25 11.8 0.4 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAN06180.1 - 1 9.4 7.1 0.93 9.5 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) C2 PF00168.30 GAN06181.1 - 1.5e-16 60.6 0.0 6.9e-16 58.4 0.0 2.2 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 GAN06181.1 - 6.9e-16 58.8 9.7 2e-10 41.0 3.0 3.6 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 GAN06181.1 - 3e-07 29.4 0.6 4.6e-06 25.5 0.1 2.6 3 0 0 3 3 3 1 Plant family of unknown function (DUF810) Clat_adaptor_s PF01217.20 GAN06182.1 - 1.6e-52 177.2 1.5 1.9e-52 177.0 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Flagellin_IN PF07196.13 GAN06182.1 - 0.0022 18.1 0.2 0.0039 17.3 0.2 1.4 1 0 0 1 1 1 1 Flagellin hook IN motif Mon1 PF03164.14 GAN06182.1 - 0.023 13.8 0.2 0.037 13.1 0.2 1.3 1 1 0 1 1 1 0 Trafficking protein Mon1 HNF-1B_C PF04812.13 GAN06182.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Septin PF00735.18 GAN06183.1 - 3.7e-58 197.0 3.2 6.3e-41 140.5 0.9 2.4 2 1 0 2 2 2 2 Septin AAA_16 PF13191.6 GAN06183.1 - 7.4e-05 23.2 0.0 0.00018 21.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAN06183.1 - 0.0002 21.4 0.1 0.00054 20.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 GAN06183.1 - 0.001 19.2 0.0 0.0035 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAN06183.1 - 0.0012 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.27 GAN06183.1 - 0.0028 17.2 0.2 0.68 9.4 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 GAN06183.1 - 0.0041 16.9 1.0 0.17 11.6 0.1 2.8 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein TsaE PF02367.17 GAN06183.1 - 0.0045 17.0 0.2 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 GAN06183.1 - 0.0068 15.8 0.1 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 GAN06183.1 - 0.012 15.7 0.3 0.64 10.0 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 GAN06183.1 - 0.014 14.9 0.1 0.033 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 GAN06183.1 - 0.045 13.5 2.2 4.2 7.1 2.2 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 GAN06183.1 - 0.05 13.9 0.8 0.21 11.8 0.1 2.5 2 1 1 3 3 3 0 AAA domain UvrD-helicase PF00580.21 GAN06183.1 - 0.066 12.7 0.8 2.1 7.8 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain G-alpha PF00503.20 GAN06183.1 - 0.076 12.2 1.0 0.85 8.7 0.0 2.2 1 1 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 GAN06183.1 - 0.078 13.4 0.1 0.47 10.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 GAN06183.1 - 0.11 12.1 0.4 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 GAN06183.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAN06183.1 - 0.13 12.6 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_transf_49 PF13896.6 GAN06184.1 - 1.2e-62 212.2 1.1 6.1e-52 177.0 0.8 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 GAN06184.1 - 0.029 14.9 0.6 0.13 12.8 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 GAN06184.1 - 0.2 11.5 1.2 0.59 9.9 0.1 2.4 2 1 1 3 3 3 0 Glycosyl transferase family 2 Mob1_phocein PF03637.17 GAN06185.1 - 2.1e-11 44.2 0.1 2.6e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family CRM1_C PF08767.11 GAN06186.1 - 2.3e-130 434.4 3.7 2.3e-129 431.2 0.3 3.0 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 GAN06186.1 - 3.1e-41 140.9 4.9 3.5e-39 134.2 2.8 4.1 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAN06186.1 - 7.1e-31 105.7 3.2 7.1e-31 105.7 3.2 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAN06186.1 - 9.4e-31 105.7 4.1 1.6e-30 105.0 2.5 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 GAN06186.1 - 3.3e-20 71.3 0.9 8e-20 70.1 0.9 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 GAN06186.1 - 2.6e-13 49.7 0.6 9e-13 47.9 0.6 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ral PF11058.8 GAN06186.1 - 0.045 13.3 3.7 0.054 13.1 0.6 2.4 2 0 0 2 2 2 0 Antirestriction protein Ral DUF1663 PF07909.11 GAN06186.1 - 0.092 11.5 0.3 0.19 10.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) HLH PF00010.26 GAN06187.1 - 1.6e-11 43.9 1.3 3.8e-11 42.8 0.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SIKE PF05769.11 GAN06187.1 - 0.018 14.9 0.4 0.047 13.6 0.4 1.6 1 0 0 1 1 1 0 SIKE family CENP-U PF13097.6 GAN06187.1 - 0.77 9.7 10.5 1.4 8.8 10.5 1.4 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF4335 PF14233.6 GAN06187.1 - 0.79 9.6 6.7 1.2 9.1 6.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4335) SRP-alpha_N PF04086.13 GAN06187.1 - 1.6 8.6 10.9 2.1 8.2 10.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DivIVA PF05103.13 GAN06187.1 - 5.2 7.2 7.9 3.7 7.6 0.1 2.6 2 1 0 2 2 2 0 DivIVA protein Ndc1_Nup PF09531.10 GAN06188.1 - 2.6e-65 221.3 9.4 3.4e-65 221.0 9.4 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TAN PF11640.8 GAN06188.1 - 0.14 12.3 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Glyco_transf_15 PF01793.16 GAN06189.1 - 3e-100 335.7 7.9 3.9e-65 220.3 5.5 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase DAPDH_C PF16654.5 GAN06189.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain RGS PF00615.19 GAN06190.1 - 5e-05 23.6 0.5 0.00019 21.6 0.1 2.1 2 1 0 2 2 2 1 Regulator of G protein signaling domain RST PF12174.8 GAN06190.1 - 0.041 13.8 0.4 0.041 13.8 0.4 1.9 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Piwi PF02171.17 GAN06191.1 - 8.4e-108 360.2 0.0 1.2e-107 359.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 GAN06191.1 - 1.5e-28 100.2 0.0 3.3e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 GAN06191.1 - 3.2e-21 74.7 0.0 1.2e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 GAN06191.1 - 2.6e-19 69.4 0.1 5e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 GAN06191.1 - 1.8e-14 53.8 0.3 4.7e-14 52.4 0.3 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 GAN06191.1 - 3e-11 43.4 0.0 2e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 Mid domain of argonaute Octopine_DH PF02317.17 GAN06191.1 - 0.092 12.8 0.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Cation_ATPase_C PF00689.21 GAN06192.1 - 2.4e-44 151.2 8.7 2.4e-44 151.2 8.7 2.4 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAN06192.1 - 4.9e-33 114.2 2.1 7.6e-33 113.5 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAN06192.1 - 6.4e-19 67.8 0.0 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN06192.1 - 2.6e-17 63.8 0.0 2.2e-16 60.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN06192.1 - 7.5e-11 41.6 0.0 1e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN06192.1 - 0.00015 21.6 0.3 0.00072 19.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_1 PF04531.13 GAN06192.1 - 2.5 8.7 0.0 2.5 8.7 0.0 4.0 4 0 0 4 4 4 0 Bacteriophage holin PI31_Prot_N PF11566.8 GAN06194.1 - 1.4e-45 155.1 0.0 1.8e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 GAN06194.1 - 1.7e-12 48.3 11.9 1.7e-12 48.3 11.9 2.7 2 1 1 3 3 3 1 PI31 proteasome regulator UPF0052 PF01933.18 GAN06195.1 - 9e-49 166.3 0.0 1.3e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 SNO PF01174.19 GAN06196.1 - 6.4e-53 179.4 0.1 7.4e-53 179.2 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAN06196.1 - 1.8e-11 44.0 0.0 2.7e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 GAN06196.1 - 1.1e-05 25.3 0.3 2.4e-05 24.2 0.3 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 GAN06196.1 - 0.00047 19.9 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 GAN06196.1 - 0.0045 16.8 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family EamA PF00892.20 GAN06197.1 - 1.1e-05 25.7 5.9 1.1e-05 25.7 5.9 2.5 2 1 1 3 3 3 2 EamA-like transporter family Peptidase_C1_2 PF03051.15 GAN06197.1 - 0.038 12.8 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family F-box-like PF12937.7 GAN06198.1 - 1.3e-05 25.0 0.1 3.2e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN06198.1 - 0.0063 16.4 1.1 0.031 14.2 0.0 2.6 3 0 0 3 3 3 1 F-box domain DEAD PF00270.29 GAN06199.1 - 4.6e-44 150.3 0.8 6.3e-44 149.8 0.2 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN06199.1 - 2.5e-33 114.8 0.1 1.2e-32 112.5 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 GAN06199.1 - 0.00073 19.9 0.7 0.02 15.2 0.4 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 GAN06199.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAN06199.1 - 0.0017 18.1 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 GAN06199.1 - 0.0063 15.3 0.0 2.1 7.0 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 GAN06199.1 - 0.043 14.1 0.3 0.14 12.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 GAN06199.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase NIF PF03031.18 GAN06200.1 - 4.9e-38 130.3 0.0 7.8e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LAMTOR PF15454.6 GAN06201.1 - 0.0022 18.6 3.1 0.0026 18.3 1.5 2.1 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DNA_pol_E_B PF04042.16 GAN06202.1 - 9.1e-40 136.3 1.0 1.8e-39 135.3 1.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 GAN06202.1 - 5.5e-22 78.9 0.6 8.5e-22 78.3 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal PrmA PF06325.13 GAN06203.1 - 1e-11 44.8 0.1 2.3e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAN06203.1 - 4.3e-11 43.4 0.1 2.2e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN06203.1 - 2.4e-10 40.9 0.0 7.8e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN06203.1 - 1.6e-09 37.8 0.0 5.1e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN06203.1 - 1.6e-06 27.7 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAN06203.1 - 4.2e-05 24.2 0.1 0.00027 21.6 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN06203.1 - 5e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAN06203.1 - 8.7e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAN06203.1 - 0.00036 20.4 0.1 0.00057 19.7 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C2H2_2 PF12756.7 GAN06203.1 - 0.00046 20.5 0.2 0.0012 19.1 0.2 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) TehB PF03848.14 GAN06203.1 - 0.002 17.6 0.3 0.0069 15.8 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB CMAS PF02353.20 GAN06203.1 - 0.0028 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 GAN06203.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase SWC7 PF17330.2 GAN06203.1 - 0.019 15.0 1.2 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Methyltransf_9 PF08003.11 GAN06203.1 - 0.02 13.8 0.3 0.045 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) UPF0020 PF01170.18 GAN06203.1 - 0.042 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 GAN06203.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 GAN06203.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PROCN PF08083.11 GAN06204.1 - 9.8e-234 775.4 6.9 1.9e-233 774.5 6.9 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GAN06204.1 - 4.7e-128 425.6 0.2 8.2e-128 424.8 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 GAN06204.1 - 9.6e-88 291.8 4.2 2.4e-87 290.5 4.2 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 GAN06204.1 - 3e-85 284.0 2.9 3e-85 284.0 2.9 2.3 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 GAN06204.1 - 2.3e-73 244.6 0.0 4.6e-73 243.6 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 GAN06204.1 - 2.7e-47 159.7 0.0 6.4e-47 158.5 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 GAN06204.1 - 2.6e-45 152.7 0.4 8e-45 151.1 0.4 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 NT-C2 PF10358.9 GAN06204.1 - 2.1e-25 89.2 1.3 4.1e-25 88.2 1.3 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins JAB PF01398.21 GAN06204.1 - 1e-07 31.9 0.0 2.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NIF PF03031.18 GAN06205.1 - 1.5e-28 99.5 0.1 1.7e-28 99.4 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase F-box-like PF12937.7 GAN06206.1 - 4.3e-05 23.3 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 GAN06206.1 - 0.0012 18.7 6.2 2.9 8.2 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich repeat Peptidase_C9 PF01707.16 GAN06206.1 - 0.018 14.6 0.1 3 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C9 LRR_4 PF12799.7 GAN06206.1 - 0.38 11.2 11.5 0.69 10.4 0.2 3.9 1 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN06206.1 - 2.8 8.8 10.1 37 5.4 0.0 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat zf-UBR PF02207.20 GAN06207.1 - 1.4e-11 44.4 8.7 1.4e-11 44.4 8.7 3.6 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 GAN06207.1 - 0.00045 20.0 12.4 0.00045 20.0 12.4 3.1 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.22 GAN06207.1 - 0.018 15.0 1.3 0.018 15.0 1.3 4.4 3 2 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Myosin_head PF00063.21 GAN06208.1 - 3.7e-235 782.2 3.7 4.6e-235 781.9 3.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAN06208.1 - 2.4e-46 157.8 0.0 5e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAN06208.1 - 1.9e-14 53.0 0.5 4.6e-14 51.7 0.5 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN06208.1 - 1.4e-13 50.4 0.1 4e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN06208.1 - 1.1e-08 34.6 0.0 3.2e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 GAN06208.1 - 0.0063 16.2 8.4 0.77 9.7 2.4 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 GAN06208.1 - 0.0063 16.1 0.2 2.1 7.8 0.1 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 GAN06208.1 - 0.012 15.8 0.0 0.047 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAN06208.1 - 0.053 14.0 0.1 2.2 8.8 0.0 3.4 4 0 0 4 4 3 0 ABC transporter SH3_3 PF08239.11 GAN06208.1 - 0.084 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_16 PF13191.6 GAN06208.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 GAN06208.1 - 0.13 12.0 0.3 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 GAN06208.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain CAF1 PF04857.20 GAN06209.1 - 1.2e-72 244.8 3.4 1.2e-72 244.8 3.4 2.1 2 0 0 2 2 2 1 CAF1 family ribonuclease RNase_T PF00929.24 GAN06209.1 - 0.016 15.8 0.4 1.8 9.1 0.1 3.1 3 0 0 3 3 3 0 Exonuclease Myc_N PF01056.18 GAN06209.1 - 0.039 13.9 6.8 0.075 12.9 6.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 GAN06209.1 - 0.067 12.0 3.3 0.14 10.9 3.3 1.5 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 GAN06209.1 - 0.1 11.0 0.5 0.17 10.3 0.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Col_cuticle_N PF01484.17 GAN06209.1 - 0.19 11.8 1.6 0.31 11.1 0.2 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Zip PF02535.22 GAN06209.1 - 0.29 10.3 1.0 0.61 9.3 1.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter MAJIN PF15077.6 GAN06209.1 - 0.68 9.7 5.5 1.9 8.2 5.5 1.7 1 0 0 1 1 1 0 Membrane-anchored junction protein FAM76 PF16046.5 GAN06209.1 - 1.2 8.4 8.8 0.11 11.8 3.5 1.9 2 0 0 2 2 2 0 FAM76 protein NPR3 PF03666.13 GAN06209.1 - 1.5 7.5 10.0 3.3 6.4 10.0 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GEMIN8 PF15348.6 GAN06209.1 - 1.7 8.9 14.1 0.2 11.9 9.2 1.9 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Nop14 PF04147.12 GAN06209.1 - 2.6 6.2 21.2 3.1 5.9 11.0 3.0 3 0 0 3 3 3 0 Nop14-like family Gti1_Pac2 PF09729.9 GAN06209.1 - 7.2 6.7 13.5 11 6.0 5.2 2.7 3 0 0 3 3 3 0 Gti1/Pac2 family Fungal_trans PF04082.18 GAN06211.1 - 8.8e-11 41.3 0.3 1.6e-09 37.2 0.3 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN06211.1 - 7.4e-07 29.2 11.0 1.5e-06 28.2 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_GLY PF01302.25 GAN06212.1 - 3.2e-19 68.7 0.1 7.5e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.31 GAN06212.1 - 6.3e-10 39.3 0.1 1.5e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Sel1 PF08238.12 GAN06213.1 - 1.9e-20 72.8 10.8 0.0016 19.1 0.0 5.8 6 0 0 6 6 6 5 Sel1 repeat CS PF04969.16 GAN06213.1 - 6.2e-13 49.6 0.1 1.9e-12 48.0 0.1 1.8 1 0 0 1 1 1 1 CS domain TPR_12 PF13424.6 GAN06213.1 - 0.0033 17.7 0.8 0.89 9.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN06213.1 - 0.052 13.7 5.0 15 6.0 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 GAN06213.1 - 0.11 12.6 3.0 3.8 7.7 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain PBP_N PF17093.5 GAN06213.1 - 0.35 11.1 0.1 0.35 11.1 0.1 1.9 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus TPR_1 PF00515.28 GAN06213.1 - 0.86 9.5 11.3 5.6 7.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CCDC158 PF15921.5 GAN06213.1 - 2.6 5.8 6.2 3.9 5.2 6.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 CAP_N PF01213.19 GAN06214.1 - 4.5e-112 374.6 1.0 4.5e-112 374.6 1.0 1.5 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GAN06214.1 - 7.8e-62 207.5 9.9 1.1e-61 207.1 9.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 GAN06214.1 - 0.00085 19.1 4.6 0.002 17.8 3.4 1.9 1 1 1 2 2 2 1 Tubulin binding cofactor C PAR1 PF06521.11 GAN06214.1 - 0.017 14.8 0.6 0.033 13.8 0.6 1.4 1 0 0 1 1 1 0 PAR1 protein TPR_11 PF13414.6 GAN06215.1 - 2.1e-09 36.9 0.5 0.00036 20.1 0.7 3.2 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 GAN06215.1 - 6.4e-05 23.1 0.5 0.46 11.0 0.1 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3510 PF12022.8 GAN06215.1 - 0.028 14.8 0.7 1.3 9.4 0.2 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) TPR_14 PF13428.6 GAN06215.1 - 0.096 13.6 0.0 1e+02 4.1 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CotH PF08757.11 GAN06216.1 - 1.2e-29 103.9 5.9 1.2e-29 103.9 5.9 1.6 2 0 0 2 2 2 1 CotH kinase protein Heme_oxygenase PF01126.20 GAN06217.1 - 2.6e-54 184.1 2.2 5.7e-54 183.0 2.2 1.6 1 0 0 1 1 1 1 Heme oxygenase XPG_N PF00752.17 GAN06217.1 - 7.9e-34 116.2 0.0 1e-32 112.6 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 GAN06217.1 - 1.4e-25 89.5 0.0 5.1e-25 87.7 0.0 2.1 1 0 0 1 1 1 1 XPG I-region Myc_N PF01056.18 GAN06217.1 - 0.0035 17.3 0.2 0.0035 17.3 0.2 3.6 3 0 0 3 3 3 1 Myc amino-terminal region Rubis-subs-bind PF09273.11 GAN06217.1 - 0.086 13.5 0.6 0.34 11.6 0.6 2.0 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding IZUMO PF15005.6 GAN06217.1 - 0.092 13.3 0.5 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated MFS_1 PF07690.16 GAN06218.1 - 1.6e-45 155.6 36.7 1.6e-45 155.6 36.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN06218.1 - 3.5e-17 62.4 10.1 3.5e-17 62.4 10.1 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAN06218.1 - 1.6e-09 36.8 7.9 2.6e-09 36.1 7.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2975 PF11188.8 GAN06218.1 - 0.01 15.7 0.6 0.01 15.7 0.6 4.2 4 2 1 5 5 5 0 Protein of unknown function (DUF2975) DUF4407 PF14362.6 GAN06218.1 - 2.8 7.2 5.2 0.42 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FH2 PF02181.23 GAN06219.1 - 2.2e-83 280.4 16.3 2.2e-83 280.4 16.3 3.0 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 GAN06219.1 - 1e-20 74.2 0.6 1e-20 74.2 0.6 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAN06219.1 - 6.1e-20 71.6 0.3 6.1e-20 71.6 0.3 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Sugarporin_N PF11471.8 GAN06219.1 - 0.013 15.5 0.6 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension T4_Rnl2_C PF18043.1 GAN06219.1 - 0.026 14.7 0.1 0.18 12.0 0.1 2.5 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal FIT1_2 PF17357.2 GAN06219.1 - 0.38 10.9 9.5 2 8.6 9.5 2.2 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 Cyclin_N PF00134.23 GAN06222.1 - 8e-19 67.6 1.9 1.2e-17 63.9 0.7 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAN06222.1 - 2.2e-07 30.8 0.1 0.00016 21.7 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 GAN06222.1 - 7.9e-05 22.7 0.6 0.00081 19.5 0.3 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin PF08613.11 GAN06222.1 - 0.23 11.8 1.3 2.1 8.7 0.2 2.1 2 0 0 2 2 2 0 Cyclin Myosin_head PF00063.21 GAN06223.1 - 5.3e-260 864.4 5.3 5.3e-260 864.4 5.3 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 GAN06223.1 - 6e-27 93.9 1.6 6e-27 93.9 1.6 3.2 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 GAN06223.1 - 7.7e-16 56.3 40.9 7e-06 25.4 1.9 7.1 7 0 0 7 7 7 4 IQ calmodulin-binding motif Myosin_N PF02736.19 GAN06223.1 - 0.0061 16.4 1.6 0.013 15.3 0.4 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain KLRAQ PF10205.9 GAN06223.1 - 0.0072 16.5 1.8 0.0072 16.5 1.8 3.5 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 GAN06223.1 - 0.011 16.1 6.0 0.49 10.8 0.4 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 GAN06223.1 - 0.013 15.9 6.3 0.013 15.9 6.3 4.8 2 2 1 3 3 3 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 GAN06223.1 - 0.014 15.4 10.2 0.03 14.4 4.8 2.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 GAN06223.1 - 0.015 15.6 0.6 0.061 13.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Retrotran_gag_3 PF14244.6 GAN06223.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AAA_16 PF13191.6 GAN06223.1 - 0.14 12.6 3.4 0.22 11.9 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain DUF5101 PF17031.5 GAN06223.1 - 0.22 11.7 6.1 22 5.2 0.4 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) HALZ PF02183.18 GAN06223.1 - 0.92 9.8 6.0 1.6 9.0 0.2 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GAN06223.1 - 1.7 8.8 16.4 0.047 13.8 1.9 3.6 3 0 0 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 GAN06223.1 - 2.4 8.1 8.3 18 5.3 0.2 3.8 1 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lzipper-MIP1 PF14389.6 GAN06223.1 - 2.4 8.5 11.2 0.31 11.4 1.7 3.9 2 2 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Peptidase_S8 PF00082.22 GAN06224.1 - 5.8e-38 130.8 7.2 5.8e-38 130.8 7.2 1.6 2 0 0 2 2 2 1 Subtilase family DUF2209 PF09974.9 GAN06224.1 - 0.019 15.3 0.0 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Inhibitor_I9 PF05922.16 GAN06224.1 - 0.049 14.3 0.6 0.096 13.4 0.6 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 Herpes_Helicase PF02689.14 GAN06225.1 - 0.0057 14.6 0.0 0.0062 14.5 0.0 1.0 1 0 0 1 1 1 1 Helicase DUF3808 PF10300.9 GAN06228.1 - 5.5e-59 200.2 0.4 1e-58 199.3 0.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 GAN06228.1 - 0.19 11.9 5.7 20 5.6 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PP2C PF00481.21 GAN06229.1 - 4.9e-53 180.4 0.0 8.4e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 GAN06229.1 - 1.9e-37 126.8 61.5 6.1e-07 29.1 0.7 10.4 4 3 7 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 GAN06229.1 - 5.6e-37 125.1 72.5 1.8e-05 25.0 2.1 13.1 8 2 5 14 14 14 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 GAN06229.1 - 1.5e-29 102.9 0.1 7.7e-29 100.6 0.0 2.2 2 1 1 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain RA PF00788.23 GAN06229.1 - 4.6e-06 27.2 0.2 1.6e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PP2C_2 PF13672.6 GAN06229.1 - 0.0017 18.1 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 GAN06229.1 - 0.14 11.7 23.1 0.88 9.0 1.0 5.3 2 1 4 6 6 6 0 Leucine-rich repeat SUIM_assoc PF16619.5 GAN06229.1 - 5.7 7.1 12.3 12 6.0 3.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 GAN06230.1 - 7.7e-59 199.2 0.0 1.3e-58 198.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06230.1 - 5.7e-45 153.6 0.0 1.2e-44 152.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN06230.1 - 8.5e-08 31.4 0.0 1.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAN06230.1 - 3.2e-06 26.7 0.0 6.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAN06230.1 - 0.11 12.4 0.1 0.31 10.9 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family PRIMA1 PF16101.5 GAN06230.1 - 0.22 11.6 11.2 1.2 9.2 1.2 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ADIP PF11559.8 GAN06230.1 - 0.42 10.7 9.7 0.97 9.5 9.0 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CAP_N PF01213.19 GAN06230.1 - 1 8.8 9.5 3 7.2 1.8 2.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal YabA PF06156.13 GAN06230.1 - 1 10.0 5.9 0.31 11.7 2.4 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Iso_dh PF00180.20 GAN06232.1 - 1.1e-81 274.7 0.1 1.6e-81 274.2 0.1 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Med22 PF06179.12 GAN06232.1 - 3e-21 75.6 4.0 3e-21 75.6 4.0 1.9 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex ABC_membrane PF00664.23 GAN06233.1 - 6.1e-62 209.8 5.0 6.1e-62 209.8 5.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAN06233.1 - 5.5e-37 127.3 0.0 1.4e-36 126.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAN06233.1 - 1.7e-05 24.4 2.1 0.0062 16.0 0.1 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN06233.1 - 8.7e-05 22.8 0.2 0.0017 18.7 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN06233.1 - 0.0011 19.4 0.0 0.0038 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAN06233.1 - 0.0039 16.9 0.2 0.01 15.6 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 GAN06233.1 - 0.013 16.0 0.1 0.23 11.9 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAN06233.1 - 0.026 15.0 0.0 0.069 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAN06233.1 - 0.053 13.1 0.0 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 GAN06233.1 - 0.06 13.1 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase PAS_5 PF07310.13 GAN06233.1 - 0.073 12.9 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 PAS domain AAA_24 PF13479.6 GAN06233.1 - 0.095 12.4 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAN06233.1 - 0.11 12.3 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAN06233.1 - 0.11 12.1 1.3 0.53 10.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAN06233.1 - 0.16 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Baculo_11_kDa PF06143.11 GAN06235.1 - 0.13 11.8 0.5 0.21 11.2 0.5 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family CHASE6_C PF17150.4 GAN06235.1 - 0.15 12.8 0.1 6.7 7.5 0.0 2.7 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain VPS9 PF02204.18 GAN06236.1 - 7.6e-24 83.9 0.2 1.8e-23 82.7 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HMGL-like PF00682.19 GAN06236.1 - 0.071 12.7 1.3 0.14 11.7 1.3 1.4 1 0 0 1 1 1 0 HMGL-like HTH_Tnp_Tc3_2 PF01498.18 GAN06238.1 - 2.1e-11 43.9 0.2 2.9e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 Transposase DNA_methylase PF00145.17 GAN06239.1 - 1.2e-29 103.7 1.4 4.2e-27 95.4 0.0 2.6 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase Plasmodium_Vir PF05795.11 GAN06239.1 - 3.6 6.9 14.7 5.7 6.3 14.7 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PP2C PF00481.21 GAN06240.1 - 4.9e-83 278.7 0.1 4.9e-83 278.7 0.1 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAN06240.1 - 5.9e-05 22.8 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C NMO PF03060.15 GAN06241.1 - 1.1e-58 199.2 0.4 3.7e-58 197.5 0.4 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAN06241.1 - 1.9e-15 56.7 0.2 2.2e-14 53.2 0.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAN06241.1 - 0.00047 19.3 0.5 0.00082 18.5 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 GAN06241.1 - 0.0056 16.2 0.2 0.014 14.9 0.1 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.17 GAN06241.1 - 0.055 12.6 1.1 0.11 11.6 0.7 1.8 2 1 0 2 2 2 0 Conserved region in glutamate synthase RapA_C PF12137.8 GAN06241.1 - 0.085 11.9 0.0 0.94 8.4 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal NanE PF04131.14 GAN06241.1 - 0.089 12.0 0.3 0.33 10.1 0.1 2.1 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Kelch_5 PF13854.6 GAN06242.1 - 8.6e-41 137.3 9.6 5.3e-10 39.1 1.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAN06242.1 - 1.5e-40 136.5 9.5 6.3e-09 35.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAN06242.1 - 3.2e-39 132.7 11.4 8.1e-08 32.2 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN06242.1 - 2.2e-38 129.8 14.2 4.5e-08 33.2 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN06242.1 - 2.2e-37 126.2 13.1 1.2e-08 34.9 0.0 6.4 3 1 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAN06242.1 - 7.1e-34 114.5 11.0 1.8e-06 27.7 0.3 6.4 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.6 GAN06242.1 - 0.0037 17.7 3.1 6.9 7.3 0.0 4.7 4 0 0 4 4 4 1 PQQ-like domain HLH PF00010.26 GAN06243.1 - 3e-18 65.5 0.2 3e-18 65.5 0.2 2.9 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain UPF0565 PF10561.9 GAN06243.1 - 0.052 12.7 1.2 0.2 10.8 1.2 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 EMC3_TMCO1 PF01956.16 GAN06243.1 - 0.15 11.8 2.1 0.36 10.6 2.1 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4407 PF14362.6 GAN06243.1 - 0.19 11.0 10.5 0.79 9.0 10.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 GAN06243.1 - 0.25 9.8 9.4 2 6.9 3.5 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family ALMT PF11744.8 GAN06243.1 - 1.9 7.2 10.2 0.73 8.6 5.0 2.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Draxin PF15550.6 GAN06243.1 - 7.5 6.3 20.0 0.1 12.5 11.1 2.4 1 1 0 2 2 2 0 Draxin TRP PF06011.12 GAN06244.1 - 8.5e-36 123.6 40.5 5.9e-34 117.5 40.5 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Fcf1 PF04900.12 GAN06245.1 - 4.2e-39 132.9 1.2 4.2e-39 132.9 1.2 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 GAN06245.1 - 6.2e-12 45.9 0.1 7.4e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 PIN like domain DUF116 PF01976.17 GAN06245.1 - 0.026 14.0 0.7 0.049 13.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF116 GlutR_N PF05201.15 GAN06245.1 - 0.1 12.4 0.4 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain NAD_binding_10 PF13460.6 GAN06246.1 - 6e-09 36.0 0.0 1.4e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAN06246.1 - 0.00011 21.8 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAN06246.1 - 0.00032 21.1 0.1 0.0012 19.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAN06246.1 - 0.0041 17.4 0.1 0.0066 16.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 GAN06246.1 - 0.011 14.9 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 GAN06246.1 - 0.028 13.5 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 GAN06246.1 - 0.031 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 KR domain SRP14 PF02290.15 GAN06247.1 - 4e-21 75.2 0.1 5.6e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Oxidored_FMN PF00724.20 GAN06248.1 - 0.0032 16.8 0.1 0.0047 16.2 0.1 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 GAN06248.1 - 0.029 13.5 0.1 0.029 13.5 0.1 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) ComA PF02679.15 GAN06248.1 - 0.048 13.1 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Ribosomal_S19 PF00203.21 GAN06249.1 - 5.9e-32 109.4 0.4 7e-32 109.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Peptidase_S28 PF05577.12 GAN06250.1 - 8e-70 235.8 0.1 9.9e-70 235.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DPBB_1 PF03330.18 GAN06251.1 - 7.7e-09 35.7 0.0 2.1e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase GRP PF07172.11 GAN06251.1 - 0.093 13.4 0.5 0.093 13.4 0.5 4.8 2 1 0 2 2 2 0 Glycine rich protein family RVT_1 PF00078.27 GAN06252.1 - 2.3e-15 56.8 0.0 3.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GAN06252.1 - 1.2e-05 25.9 1.0 3.3e-05 24.5 1.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Macoilin PF09726.9 GAN06252.1 - 0.096 11.2 0.6 0.13 10.8 0.6 1.1 1 0 0 1 1 1 0 Macoilin family Ran_BP1 PF00638.18 GAN06253.1 - 2.2e-20 73.1 0.2 6e-20 71.7 0.2 1.8 1 0 0 1 1 1 1 RanBP1 domain DUF4757 PF15949.5 GAN06253.1 - 0.34 11.3 13.5 1.3 9.5 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) DUF2428 PF10350.9 GAN06254.1 - 2.9e-80 269.5 0.0 6.3e-80 268.4 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 GAN06254.1 - 0.014 15.6 5.9 38 4.9 0.0 6.4 6 0 0 6 6 6 0 HEAT repeat Ribonuc_red_lgC PF02867.15 GAN06255.1 - 4.3e-189 629.4 0.0 5.6e-189 629.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAN06255.1 - 1.6e-24 85.7 0.0 4e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAN06255.1 - 1.9e-17 63.6 0.2 1.2e-16 61.0 0.0 2.5 3 0 0 3 3 3 1 ATP cone domain Glyco_transf_15 PF01793.16 GAN06256.1 - 8.3e-112 373.6 14.6 1e-111 373.3 14.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CD20 PF04103.15 GAN06256.1 - 0.075 13.1 0.1 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 CD20-like family SH3_9 PF14604.6 GAN06257.1 - 6.7e-44 147.5 0.2 1.2e-15 57.1 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 GAN06257.1 - 7e-38 128.0 2.7 2.1e-11 43.2 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 GAN06257.1 - 4.2e-35 119.2 0.0 4e-10 39.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 GAN06257.1 - 0.085 13.1 3.0 7 7.0 0.1 3.4 3 0 0 3 3 3 0 Bacterial SH3 domain XFP PF03894.15 GAN06257.1 - 0.15 11.7 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPR_2 PF07719.17 GAN06258.1 - 2e-06 27.5 1.8 0.021 14.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN06258.1 - 2.2e-06 27.2 3.4 0.00052 19.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN06258.1 - 2.3e-05 24.6 0.7 0.0023 18.2 0.3 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN06258.1 - 2.3e-05 24.4 0.7 0.00014 22.0 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAN06258.1 - 5.1e-05 23.3 0.2 0.0012 19.0 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN06258.1 - 0.00034 20.2 1.1 0.0013 18.4 0.6 2.1 1 1 1 2 2 2 1 TPR repeat TPR_10 PF13374.6 GAN06258.1 - 0.00047 19.9 1.6 0.04 13.8 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06258.1 - 0.0019 18.7 1.0 0.0042 17.6 1.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN06258.1 - 0.0045 16.4 0.1 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 MalT-like TPR region Glyco_hydro_4 PF02056.16 GAN06258.1 - 0.0062 16.1 1.1 0.0063 16.1 0.2 1.4 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase TPR_8 PF13181.6 GAN06258.1 - 0.0098 16.0 3.2 4.7 7.7 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN06258.1 - 0.013 16.1 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Tektin PF03148.14 GAN06258.1 - 0.015 14.1 1.2 0.021 13.6 1.2 1.2 1 0 0 1 1 1 0 Tektin family TPR_14 PF13428.6 GAN06258.1 - 0.16 12.8 0.6 12 7.1 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Asp PF00026.23 GAN06259.1 - 3.8e-78 263.1 0.6 5.2e-78 262.6 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_L34e PF01199.18 GAN06259.1 - 6.4e-44 148.2 6.1 1.3e-43 147.2 6.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L34e RRM_1 PF00076.22 GAN06259.1 - 1.6e-15 56.7 0.1 3e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAXi_C PF14541.6 GAN06259.1 - 7.5e-07 29.1 0.0 2.1e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal RRM_5 PF13893.6 GAN06259.1 - 8.9e-07 28.6 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAXi_N PF14543.6 GAN06259.1 - 5.2e-06 26.8 0.0 0.00096 19.4 0.1 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN06259.1 - 0.0018 18.9 0.0 3.5 8.3 0.0 3.7 3 1 0 3 3 3 1 Aspartyl protease MFS_1 PF07690.16 GAN06260.1 - 1.5e-12 47.1 28.2 1.7e-12 46.9 22.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 GAN06260.1 - 3e-08 33.4 2.6 3e-08 33.4 2.6 2.2 2 1 0 2 2 2 1 Nodulin-like Sel1 PF08238.12 GAN06262.1 - 2.2e-40 136.2 16.9 5.9e-09 36.3 0.1 7.1 7 0 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.6 GAN06262.1 - 0.0059 17.2 5.3 0.8 10.5 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAN06262.1 - 0.056 13.7 0.2 3.3 8.2 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Rho_Binding PF08912.11 GAN06262.1 - 0.55 11.1 7.6 1.9 9.4 7.6 1.9 1 0 0 1 1 1 0 Rho Binding Nnf1 PF03980.14 GAN06263.1 - 0.045 14.1 0.7 0.045 14.1 0.7 3.0 3 1 0 3 3 3 0 Nnf1 Lentiviral_Tat PF02998.14 GAN06263.1 - 0.098 12.7 1.0 0.41 10.7 0.1 2.2 1 1 1 2 2 2 0 Lentiviral Tat protein UPF0147 PF03685.13 GAN06263.1 - 0.36 10.9 5.8 0.39 10.8 0.2 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) DUF4407 PF14362.6 GAN06263.1 - 0.37 10.1 11.5 0.42 9.9 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sbi-IV PF11621.8 GAN06263.1 - 0.59 10.5 0.1 0.59 10.5 0.1 3.2 2 1 2 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI Metal_resist PF13801.6 GAN06263.1 - 1.3 9.2 10.2 0.65 10.2 2.0 2.9 3 0 0 3 3 3 0 Heavy-metal resistance Ku_C PF03730.14 GAN06263.1 - 2.3 9.0 12.3 2.8 8.7 9.2 2.4 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF641 PF04859.12 GAN06263.1 - 4.3 7.7 18.1 2.1 8.7 12.4 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) zf-CCCH_6 PF18585.1 GAN06263.1 - 4.3 7.3 4.8 11 6.0 0.5 2.5 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 LMBR1 PF04791.16 GAN06263.1 - 8.1 5.2 9.2 10 4.9 9.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4446 PF14584.6 GAN06263.1 - 9.3 6.2 14.5 6.3 6.8 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) SOGA PF11365.8 GAN06263.1 - 9.3 7.5 19.1 4.1 8.6 0.7 3.0 1 1 2 3 3 3 0 Protein SOGA DUF87 PF01935.17 GAN06263.1 - 9.4 6.3 11.7 28 4.7 11.7 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain OmpH PF03938.14 GAN06263.1 - 9.4 6.6 29.6 66 3.8 28.6 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LAMTOR5 PF16672.5 GAN06264.1 - 1.5e-21 76.1 0.0 1.6e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 GAN06264.1 - 1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain GrpE PF01025.19 GAN06265.1 - 2.5e-47 160.6 2.2 3.5e-47 160.2 2.2 1.1 1 0 0 1 1 1 1 GrpE SF-assemblin PF06705.11 GAN06265.1 - 0.0018 17.7 3.3 0.0026 17.1 3.3 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin PRP38 PF03371.15 GAN06265.1 - 0.044 13.7 0.2 0.084 12.7 0.2 1.4 1 0 0 1 1 1 0 PRP38 family DUF4085 PF13315.6 GAN06265.1 - 0.16 11.6 3.2 0.28 10.8 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) Baculo_PEP_C PF04513.12 GAN06265.1 - 0.38 10.8 2.1 1.6 8.8 2.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 GAN06265.1 - 3.3 8.3 6.0 15 6.2 0.3 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Nramp PF01566.18 GAN06266.1 - 2.5e-100 335.9 26.1 1e-46 159.6 6.6 3.5 4 0 0 4 4 4 3 Natural resistance-associated macrophage protein ArfGap PF01412.18 GAN06267.1 - 1.8e-35 121.6 0.1 5.4e-35 120.0 0.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5600 PF18150.1 GAN06268.1 - 1.9e-39 134.5 2.7 4e-39 133.5 2.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 GAN06268.1 - 3.8e-16 58.9 0.0 2.2e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 GAN06268.1 - 6.1e-14 51.6 0.0 1.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 GAN06268.1 - 1.9e-12 47.6 0.0 1.7e-11 44.5 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAN06268.1 - 1.1e-07 31.9 0.0 3.6e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 GAN06268.1 - 7.9e-05 21.9 0.0 0.00028 20.2 0.0 2.1 1 0 0 1 1 1 1 EF hand GTP_EFTU PF00009.27 GAN06268.1 - 0.00026 20.6 0.0 0.00063 19.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAN06268.1 - 0.00028 21.1 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAN06268.1 - 0.00038 19.9 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_6 PF13405.6 GAN06268.1 - 0.01 15.7 0.0 0.061 13.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Ras PF00071.22 GAN06268.1 - 0.026 14.1 0.3 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 GAN06268.1 - 0.027 14.0 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 GAN06268.1 - 0.092 12.2 0.1 3 7.2 0.0 2.8 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 GAN06268.1 - 0.16 12.0 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Yip1 PF04893.17 GAN06269.1 - 1.4e-18 67.2 15.4 2.6e-18 66.3 15.4 1.4 1 1 0 1 1 1 1 Yip1 domain TRAPP PF04051.16 GAN06270.1 - 2.2e-46 157.2 0.0 2.7e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LT-IIB PF06453.11 GAN06270.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Kelch_5 PF13854.6 GAN06271.1 - 1.4e-15 56.9 0.0 0.00042 20.2 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 GAN06271.1 - 1.9e-15 56.6 0.0 8.5e-06 25.7 0.0 4.3 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN06271.1 - 5.7e-14 51.8 0.1 6.1e-06 26.3 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 GAN06271.1 - 1.3e-10 40.8 0.0 0.0026 17.7 0.0 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAN06271.1 - 1.1e-09 38.3 0.4 2.6e-05 24.4 0.0 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN06271.1 - 1.5e-09 37.2 0.0 0.00044 19.8 0.0 3.1 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 GAN06271.1 - 1.4e-07 31.7 0.1 3.7e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain Arrestin_C PF02752.22 GAN06272.1 - 9.9e-23 81.1 0.0 1e-18 68.1 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN06272.1 - 1.8e-10 41.1 0.0 4.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN06272.1 - 0.0061 16.3 0.1 0.048 13.4 0.1 2.2 1 1 0 1 1 1 1 Arrestin_N terminal like Rgp1 PF08737.10 GAN06272.1 - 0.016 14.4 0.1 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Rgp1 Pkinase PF00069.25 GAN06273.1 - 7.6e-62 209.1 0.8 3.3e-61 207.0 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06273.1 - 1.1e-25 90.4 0.0 2.1e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN06273.1 - 4.2e-08 32.5 0.4 1e-07 31.3 0.4 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN06273.1 - 1.6e-07 30.9 0.5 3.3e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAN06273.1 - 2.9e-06 27.0 0.9 8e-06 25.6 0.4 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 GAN06273.1 - 3.1e-06 26.2 0.1 9.3e-06 24.7 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAN06273.1 - 1e-05 25.6 0.2 0.00017 21.6 0.6 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN06273.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.7 GAN06273.1 - 0.0069 16.6 0.0 0.041 14.2 0.0 2.2 2 0 0 2 2 2 1 PAS domain SUV3_C PF12513.8 GAN06274.1 - 1.3e-14 53.9 0.4 5.6e-14 51.8 0.1 2.4 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 GAN06274.1 - 2.6e-11 43.2 0.3 9.4e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 GAN06274.1 - 7.7e-11 42.3 0.0 2.1e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_N PF18114.1 GAN06274.1 - 0.088 12.9 0.2 0.3 11.2 0.2 1.9 1 0 0 1 1 1 0 Suv3 helical N-terminal domain AAA_22 PF13401.6 GAN06274.1 - 0.11 12.8 0.1 1 9.6 0.1 2.6 1 1 0 1 1 1 0 AAA domain DUF5638 PF18688.1 GAN06276.1 - 0.023 15.0 0.6 0.032 14.5 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5638) Act-Frag_cataly PF09192.10 GAN06276.1 - 0.062 12.7 0.2 0.066 12.6 0.2 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Phe_tRNA-synt_N PF02912.18 GAN06276.1 - 0.38 10.7 3.3 14 5.7 0.4 2.6 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain LRR_9 PF14580.6 GAN06277.1 - 4.5e-60 202.1 4.7 6.1e-60 201.7 4.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GAN06277.1 - 3.1e-06 27.4 19.6 0.00017 21.9 8.4 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAN06277.1 - 1.5e-05 24.6 8.5 1.5e-05 24.6 8.5 2.6 2 1 1 3 3 3 2 Leucine rich repeat Cactin_mid PF10312.9 GAN06278.1 - 4.9e-66 222.2 5.3 4.9e-66 222.2 5.3 2.2 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 GAN06278.1 - 1.4e-60 202.7 7.5 2.6e-60 201.9 7.5 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Amidohydro_1 PF01979.20 GAN06280.1 - 2.4e-71 240.9 2.6 3.6e-71 240.3 2.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 GAN06280.1 - 1.5e-55 186.7 1.2 3.2e-55 185.7 1.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 GAN06280.1 - 7.1e-42 141.7 0.1 1.8e-41 140.4 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 GAN06280.1 - 3e-41 139.4 0.0 6.3e-41 138.4 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 GAN06280.1 - 7.8e-06 25.6 0.0 0.00046 19.8 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family HTH_5 PF01022.20 GAN06280.1 - 0.11 12.4 0.2 15 5.5 0.1 2.9 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Abhydrolase_3 PF07859.13 GAN06281.1 - 1.5e-43 149.1 0.1 2.6e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN06281.1 - 1.9e-16 59.9 0.0 9.4e-16 57.6 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 GAN06281.1 - 0.01 14.7 0.2 0.04 12.8 0.2 1.7 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_6 PF12697.7 GAN06281.1 - 0.019 15.5 1.8 0.024 15.2 0.8 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 GAN06281.1 - 0.085 12.6 0.1 5.9 6.5 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Gemini_AL1_M PF08283.11 GAN06281.1 - 0.12 12.5 0.5 0.45 10.6 0.3 2.0 2 0 0 2 2 2 0 Geminivirus rep protein central domain Hydrolase_4 PF12146.8 GAN06281.1 - 0.14 11.4 0.0 0.45 9.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Myotoxins PF00819.17 GAN06281.1 - 0.29 11.4 2.2 0.64 10.3 2.2 1.5 1 0 0 1 1 1 0 Myotoxin, crotamine CP2 PF04516.15 GAN06282.1 - 2.1e-49 167.9 8.0 6.3e-48 163.1 8.0 2.5 1 1 0 1 1 1 1 CP2 transcription factor p450 PF00067.22 GAN06283.1 - 5.8e-71 239.6 0.1 7.7e-71 239.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nas2_N PF18265.1 GAN06284.1 - 1.1e-29 102.2 0.9 2.4e-29 101.1 0.5 1.8 1 1 1 2 2 2 1 Nas2 N_terminal domain PDZ_2 PF13180.6 GAN06284.1 - 8.8e-09 35.6 0.1 5.7e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAN06284.1 - 8.1e-08 32.0 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 GAN06284.1 - 2.2e-06 28.0 0.0 4.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 GAN06284.1 - 6.5e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Mei5 PF10376.9 GAN06284.1 - 0.0017 18.3 2.9 0.19 11.5 0.0 2.9 3 0 0 3 3 3 1 Double-strand recombination repair protein APG6_N PF17675.1 GAN06284.1 - 0.015 15.8 0.1 4.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region HALZ PF02183.18 GAN06284.1 - 0.016 15.4 0.4 0.043 14.0 0.4 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Prefoldin_2 PF01920.20 GAN06284.1 - 0.034 14.1 0.4 0.78 9.7 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit DegS PF05384.11 GAN06284.1 - 0.038 13.5 1.4 1.2 8.6 0.0 2.5 3 0 0 3 3 3 0 Sensor protein DegS DUF5082 PF16888.5 GAN06284.1 - 0.044 14.0 2.7 0.17 12.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF948 PF06103.11 GAN06284.1 - 0.052 13.8 1.5 0.26 11.6 0.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 GAN06284.1 - 0.097 12.7 3.1 0.72 9.9 0.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 GAN06284.1 - 0.5 10.5 4.2 0.6 10.3 1.6 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Enkurin PF13864.6 GAN06284.1 - 2.9 8.4 5.1 0.96 9.9 0.4 2.3 3 0 0 3 3 3 0 Calmodulin-binding SDA1 PF05285.12 GAN06285.1 - 0.032 13.7 35.3 0.041 13.3 35.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GAN06285.1 - 0.091 12.1 32.4 0.13 11.6 32.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAN06285.1 - 0.16 10.1 31.7 0.19 9.9 31.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GAN06285.1 - 0.19 10.3 38.6 0.28 9.7 38.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.12 GAN06285.1 - 0.27 9.6 24.2 0.39 9.1 24.2 1.3 1 0 0 1 1 1 0 Mpp10 protein V_ATPase_I PF01496.19 GAN06285.1 - 0.87 7.4 8.3 1.1 7.1 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_capsid PF06112.11 GAN06285.1 - 1.1 9.3 10.6 1.7 8.7 10.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SAPS PF04499.15 GAN06285.1 - 1.2 7.8 9.0 1.2 7.8 9.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.6 GAN06285.1 - 2.2 8.2 7.7 3.6 7.5 7.7 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF4746 PF15928.5 GAN06285.1 - 2.7 7.4 10.5 3.4 7.0 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 GAN06285.1 - 5 6.0 22.4 7 5.5 22.4 1.2 1 0 0 1 1 1 0 Paf1 LSM PF01423.22 GAN06286.1 - 3.3e-19 68.3 0.1 3.8e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAN06286.1 - 0.0005 20.2 0.0 0.00058 19.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 GAN06286.1 - 0.0029 17.6 0.1 0.0033 17.5 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain F_bP_aldolase PF01116.20 GAN06287.1 - 5e-93 311.6 0.0 5.7e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.17 GAN06287.1 - 0.085 12.3 0.8 1.3 8.5 0.1 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain CN_hydrolase PF00795.22 GAN06288.1 - 2.6e-07 30.3 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1308 PF07000.11 GAN06290.1 - 8.2e-22 77.9 0.0 5.5e-20 71.9 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 GAN06290.1 - 5e-16 58.7 0.8 1.2e-11 44.3 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5614) ADPrib_exo_Tox PF03496.14 GAN06291.1 - 0.0034 16.7 0.1 0.006 15.9 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme DUF747 PF05346.11 GAN06292.1 - 6.2e-113 377.5 13.1 7.9e-113 377.1 13.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family SPATA48 PF15073.6 GAN06292.1 - 0.085 13.2 2.3 0.18 12.1 2.3 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 DUF4834 PF16118.5 GAN06292.1 - 0.34 11.9 1.7 2.3 9.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) MMR_HSR1 PF01926.23 GAN06293.1 - 2.9e-08 33.8 0.0 4.5e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN06293.1 - 4e-06 26.5 0.0 8.5e-05 22.2 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN06293.1 - 2.1e-05 24.5 0.0 0.00033 20.6 0.0 2.7 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAN06293.1 - 0.006 16.1 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B TniB PF05621.11 GAN06293.1 - 0.023 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 GAN06293.1 - 0.026 14.8 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN06293.1 - 0.035 13.7 0.0 0.55 9.8 0.0 2.4 2 0 0 2 2 2 0 Ras family RNA_helicase PF00910.22 GAN06293.1 - 0.051 14.0 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 GAN06293.1 - 0.68 10.0 4.0 11 6.0 0.1 3.3 3 1 0 3 3 3 0 Dynamin family Macoilin PF09726.9 GAN06294.1 - 0.0025 16.5 0.3 0.0025 16.5 0.3 1.6 2 0 0 2 2 2 1 Macoilin family eIF-4B PF06273.11 GAN06294.1 - 0.0046 16.1 0.9 0.0069 15.5 0.9 1.1 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B AAT PF03417.16 GAN06294.1 - 0.016 14.9 2.2 0.037 13.7 2.2 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MPS2 PF17060.5 GAN06294.1 - 0.02 14.2 0.5 0.02 14.2 0.5 1.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 KLRAQ PF10205.9 GAN06294.1 - 0.025 14.8 5.1 0.078 13.2 5.1 1.9 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein ERM PF00769.19 GAN06294.1 - 0.063 13.1 7.4 0.12 12.2 7.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family RXLR PF16810.5 GAN06294.1 - 0.68 10.4 5.3 1.6 9.1 2.2 2.5 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity p450 PF00067.22 GAN06295.1 - 1.1e-66 225.5 0.2 1.2e-66 225.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 GPAT_N PF14829.6 GAN06295.1 - 0.16 12.0 3.6 0.19 11.7 0.8 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal HEAT_EZ PF13513.6 GAN06296.1 - 5.4e-18 65.1 10.8 7.5e-09 35.9 0.0 8.6 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.22 GAN06296.1 - 2.1e-12 46.2 11.8 0.0051 17.0 0.1 9.0 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 GAN06296.1 - 4.3e-12 46.3 0.1 0.0071 16.7 0.0 6.0 5 2 1 6 6 6 3 HEAT repeats IBN_N PF03810.19 GAN06296.1 - 9.3e-11 41.5 0.2 4.2e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 GAN06296.1 - 5.7e-10 39.7 0.0 0.36 11.4 0.0 6.5 4 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN06296.1 - 6.3e-06 26.3 0.0 0.059 13.4 0.0 4.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 GAN06296.1 - 0.013 15.0 0.2 0.088 12.3 0.0 2.6 3 0 0 3 3 3 0 Tti2 family RRN3 PF05327.11 GAN06296.1 - 0.027 13.0 2.5 0.055 12.0 2.5 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 V-ATPase_H_C PF11698.8 GAN06296.1 - 0.12 12.5 0.0 0.49 10.5 0.0 2.1 1 0 0 1 1 1 0 V-ATPase subunit H Drc1-Sld2 PF11719.8 GAN06296.1 - 0.85 9.1 5.3 4.7 6.6 0.0 2.1 2 0 0 2 2 2 0 DNA replication and checkpoint protein FYVE PF01363.21 GAN06297.1 - 7.9e-15 54.8 9.6 7.9e-15 54.8 9.6 3.3 3 1 0 3 3 3 1 FYVE zinc finger zf-trcl PF13451.6 GAN06297.1 - 0.027 14.4 1.8 0.027 14.4 1.8 2.5 2 1 1 3 3 3 0 Probable zinc-ribbon domain BLOC1_2 PF10046.9 GAN06297.1 - 1.8 8.9 7.5 0.29 11.5 2.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-AN1 PF01428.16 GAN06297.1 - 2.3 8.5 12.3 0.68 10.1 7.5 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger PNK3P PF08645.11 GAN06298.1 - 9.8e-58 194.4 0.3 2e-57 193.4 0.3 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 GAN06298.1 - 9.1e-17 61.6 0.1 6.1e-14 52.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain Hydrolase_6 PF13344.6 GAN06298.1 - 0.00037 20.6 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 GAN06298.1 - 0.00062 19.1 0.1 0.58 9.4 0.1 2.4 1 1 1 2 2 2 2 Zeta toxin HAD_2 PF13419.6 GAN06298.1 - 0.0015 18.7 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase KTI12 PF08433.10 GAN06298.1 - 0.012 15.1 4.0 1.6 8.1 0.9 2.8 2 1 1 3 3 3 0 Chromatin associated protein KTI12 HAD PF12710.7 GAN06298.1 - 0.03 14.7 0.1 0.18 12.2 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MMR_HSR1 PF01926.23 GAN06298.1 - 0.096 12.8 0.0 0.36 10.9 0.0 2.0 2 1 1 3 3 3 0 50S ribosome-binding GTPase Hydrolase PF00702.26 GAN06298.1 - 0.16 12.3 0.1 3.1 8.0 0.1 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SNAPc_SNAP43 PF09808.9 GAN06299.1 - 8.3e-30 104.1 7.9 1.3e-29 103.5 7.9 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 MOZART1 PF12554.8 GAN06299.1 - 1.9e-22 78.7 0.3 3.7e-22 77.8 0.3 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Xan_ur_permease PF00860.20 GAN06300.1 - 7.2e-60 202.7 35.3 2.2e-56 191.2 28.2 2.2 1 1 1 2 2 2 2 Permease family COPI_C PF06957.11 GAN06302.1 - 2.8e-146 487.4 0.0 3.6e-146 487.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 GAN06302.1 - 1.1e-130 436.7 1.3 1.1e-130 436.7 1.3 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAN06302.1 - 6.1e-36 121.8 12.2 3.2e-08 34.1 0.1 7.9 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 GAN06302.1 - 0.00017 20.4 6.6 0.28 9.8 0.1 4.3 2 2 2 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN06302.1 - 0.00033 20.9 1.7 4.6 7.6 0.0 4.8 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 GAN06302.1 - 0.027 14.3 0.1 0.086 12.7 0.1 1.9 1 0 0 1 1 1 0 Region in Clathrin and VPS Importin_rep_6 PF18829.1 GAN06302.1 - 0.17 12.0 2.0 0.42 10.8 2.0 1.6 1 0 0 1 1 1 0 Importin repeat 6 Mito_carr PF00153.27 GAN06304.1 - 7.5e-61 202.1 0.7 3.2e-22 78.2 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein FAT PF02259.23 GAN06306.1 - 6.3e-66 222.9 13.4 2.8e-65 220.8 13.4 2.3 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 GAN06306.1 - 6.7e-28 98.2 1.6 1.1e-27 97.4 0.2 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAN06306.1 - 6e-06 26.0 0.6 2e-05 24.3 0.6 2.0 1 0 0 1 1 1 1 FATC domain RasGEF_N_2 PF14663.6 GAN06306.1 - 0.059 13.8 1.3 1.7 9.1 0.1 3.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain NuiA PF07924.11 GAN06306.1 - 0.18 12.2 1.5 0.49 10.8 0.1 2.5 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein RIX1 PF08167.12 GAN06306.1 - 1.2 8.8 11.9 0.14 11.9 0.1 5.6 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis Sugar_tr PF00083.24 GAN06307.1 - 1.4e-130 436.2 25.6 1.6e-130 436.0 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN06307.1 - 3.6e-25 88.6 39.6 2e-18 66.5 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2655 PF10848.8 GAN06307.1 - 0.14 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) Ldh_1_C PF02866.18 GAN06308.1 - 1.4e-48 164.9 0.3 5.1e-48 163.2 0.4 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAN06308.1 - 1.9e-45 154.4 0.0 3.2e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAN06308.1 - 0.0001 21.4 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GAN06308.1 - 0.0029 18.0 0.3 0.0098 16.3 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAN06308.1 - 0.0051 16.9 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.16 GAN06308.1 - 0.011 15.3 0.1 0.54 9.8 0.1 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 GAN06308.1 - 0.082 12.2 0.6 0.57 9.5 0.1 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PfkB PF00294.24 GAN06309.1 - 1.8e-30 106.3 0.3 2.4e-29 102.6 0.3 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DFP PF04127.15 GAN06309.1 - 0.0044 16.9 0.2 0.011 15.5 0.2 1.7 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Pup_ligase PF03136.15 GAN06309.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Pup-ligase protein B56 PF01603.20 GAN06310.1 - 6.1e-187 621.7 9.3 6.1e-187 621.7 9.3 1.4 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) APOBEC2 PF18772.1 GAN06310.1 - 0.047 13.7 0.9 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 APOBEC2 DUF5090 PF17009.5 GAN06310.1 - 0.051 13.5 0.8 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) NAD1 PF18778.1 GAN06310.1 - 0.092 12.8 2.5 6.2 6.9 0.4 2.5 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 zf-C2H2_jaz PF12171.8 GAN06311.1 - 7.6e-05 22.9 0.1 0.00015 22.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN06311.1 - 0.00033 20.9 1.0 0.00058 20.2 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAN06311.1 - 0.049 14.0 2.2 0.14 12.5 2.2 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Chondroitinas_B PF14592.6 GAN06311.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Chondroitinase B DUF4674 PF15719.5 GAN06311.1 - 2.7 8.0 10.3 0.59 10.1 6.1 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4674) DUF702 PF05142.12 GAN06311.1 - 3.1 8.2 10.0 0.097 13.1 3.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF702) RRM_1 PF00076.22 GAN06312.1 - 5.4e-31 106.2 0.1 7.3e-15 54.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN06312.1 - 6.8e-06 26.0 0.2 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 GAN06312.1 - 0.013 15.3 2.2 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Lys-AminoMut_A PF09043.11 GAN06312.1 - 0.27 9.6 4.6 0.39 9.1 4.6 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Herpes_pp85 PF04637.12 GAN06312.1 - 1.5 7.1 4.0 2.3 6.5 4.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Siah-Interact_N PF09032.11 GAN06312.1 - 1.8 8.9 19.0 2.2 8.7 16.7 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal LMBR1 PF04791.16 GAN06312.1 - 9.5 5.0 8.0 14 4.4 8.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pro_isomerase PF00160.21 GAN06313.1 - 1.2e-55 188.1 0.0 1.4e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 GAN06313.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) PLDc_N PF13396.6 GAN06314.1 - 1e-11 44.5 3.3 1e-11 44.5 3.3 1.4 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF805 PF05656.14 GAN06314.1 - 0.18 12.2 1.4 0.37 11.2 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF3285 PF11688.8 GAN06314.1 - 8 6.5 6.3 2.1 8.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Na_H_Exchanger PF00999.21 GAN06315.1 - 1.6e-62 211.5 23.2 2e-62 211.2 23.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 GAN06315.1 - 0.015 15.4 0.2 0.015 15.4 0.2 2.9 4 0 0 4 4 4 0 YrhC-like protein DUF2754 PF10953.8 GAN06315.1 - 0.087 13.1 1.3 1.1 9.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) RELT PF12606.8 GAN06315.1 - 2.3 7.3 5.4 9.2 5.4 5.4 2.1 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 WW PF00397.26 GAN06316.1 - 3.1e-05 24.0 0.2 6.8e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 WW domain GAT PF03127.14 GAN06317.1 - 0.023 15.0 0.9 0.032 14.5 0.9 1.2 1 0 0 1 1 1 0 GAT domain COMMD1_N PF17221.3 GAN06317.1 - 0.034 14.4 0.1 0.048 13.9 0.1 1.2 1 0 0 1 1 1 0 COMMD1 N-terminal domain FAD_binding_1 PF00667.20 GAN06318.1 - 1.4e-54 185.0 0.0 2.2e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN06318.1 - 3.4e-31 108.4 0.3 1.1e-30 106.8 0.2 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GAN06318.1 - 3e-19 69.7 0.0 1e-18 67.9 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 GAN06318.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain Sin3a_C PF16879.5 GAN06319.1 - 0.03 14.0 1.3 0.054 13.2 1.3 1.4 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein Nucleoporin_FG2 PF15967.5 GAN06320.1 - 0.012 14.2 1.5 0.016 13.8 1.5 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region HMMR_N PF15905.5 GAN06320.1 - 3.5 7.0 28.7 20 4.5 28.7 2.2 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tup_N PF08581.10 GAN06320.1 - 3.8 7.9 25.0 0.24 11.7 8.4 3.7 1 1 2 3 3 3 0 Tup N-terminal DUF4407 PF14362.6 GAN06320.1 - 8.1 5.7 16.8 12 5.2 16.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L18_c PF14204.6 GAN06321.1 - 6.5e-22 78.3 4.8 7.9e-22 78.0 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region zf-3CxxC_2 PF17180.4 GAN06322.1 - 3.1e-11 43.9 9.8 3.1e-11 43.9 9.8 1.9 2 0 0 2 2 2 1 Zinc-binding domain CLPTM1 PF05602.12 GAN06322.1 - 0.011 14.8 1.3 0.014 14.5 1.3 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) zf-3CxxC PF13695.6 GAN06322.1 - 0.12 12.9 17.0 3.4 8.2 13.9 3.4 2 1 0 2 2 2 0 Zinc-binding domain UPF0515 PF15135.6 GAN06322.1 - 0.53 9.6 10.3 0.68 9.2 4.9 2.0 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Fer4_9 PF13187.6 GAN06322.1 - 2.4 8.4 8.0 1.4 9.2 4.8 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain HypA PF01155.19 GAN06322.1 - 5.1 7.1 7.0 17 5.4 7.0 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HECT PF00632.25 GAN06323.1 - 5.6e-69 233.0 1.2 8.6e-69 232.3 0.1 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF5494 PF17598.2 GAN06324.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5494) Sec63 PF02889.16 GAN06325.1 - 6e-146 484.4 0.1 9.6e-80 267.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAN06325.1 - 3.9e-52 176.6 0.2 1.8e-26 93.0 0.3 3.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 GAN06325.1 - 1.3e-25 90.4 0.0 6.9e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN06325.1 - 1e-17 64.5 0.0 1.5e-07 31.8 0.0 3.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAN06325.1 - 8.8e-07 29.3 0.1 0.12 12.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAN06325.1 - 1.2e-06 28.4 0.0 0.03 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 GAN06325.1 - 2.5e-06 27.6 0.1 5.9e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA PF00004.29 GAN06325.1 - 2e-05 25.0 0.9 0.078 13.4 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 GAN06325.1 - 0.00045 20.6 1.0 0.061 13.7 0.2 2.8 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 GAN06325.1 - 0.03 14.1 0.2 7.5 6.3 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 GAN06325.1 - 0.046 13.3 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAN06325.1 - 0.077 12.4 0.0 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 GAN06325.1 - 0.16 11.5 3.8 5.9 6.3 0.0 3.7 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 GAN06325.1 - 3.9 7.2 5.0 23 4.6 0.0 3.6 4 1 1 5 5 5 0 AAA domain Gp_dh_C PF02800.20 GAN06326.1 - 1.4e-69 232.7 0.0 1.9e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAN06326.1 - 3.7e-41 139.6 0.1 8.7e-41 138.4 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Arf PF00025.21 GAN06327.1 - 2.9e-46 157.1 0.0 3.6e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAN06327.1 - 8.6e-12 44.9 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN06327.1 - 9.2e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAN06327.1 - 1.2e-10 41.1 0.1 2.7e-07 30.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAN06327.1 - 1.9e-09 37.2 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAN06327.1 - 7.4e-09 35.4 0.1 4.8e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN06327.1 - 8.2e-09 35.2 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN06327.1 - 2.8e-08 33.8 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAN06327.1 - 0.0078 16.7 0.0 0.0083 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 GAN06327.1 - 0.034 13.7 0.1 0.089 12.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 GAN06327.1 - 0.045 14.0 0.0 0.17 12.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 GAN06327.1 - 0.087 13.4 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2672 PF10878.8 GAN06327.1 - 0.1 12.5 0.9 3.3 7.7 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2672) AAA_29 PF13555.6 GAN06327.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 GAN06327.1 - 0.2 11.3 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Choline_kinase PF01633.20 GAN06328.1 - 6e-56 189.4 0.4 1.1e-55 188.6 0.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAN06328.1 - 3.3e-07 30.5 0.0 4.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAN06328.1 - 0.0091 15.3 0.1 0.11 11.8 0.2 2.4 2 1 0 2 2 2 1 Ecdysteroid kinase IL11 PF07400.11 GAN06328.1 - 0.048 13.3 1.4 0.099 12.3 0.8 1.7 2 0 0 2 2 2 0 Interleukin 11 RTX PF02382.15 GAN06328.1 - 0.09 12.4 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein Maelstrom PF13017.6 GAN06328.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 piRNA pathway germ-plasm component DnaJ PF00226.31 GAN06329.1 - 2.5e-16 59.6 0.4 4.2e-16 58.8 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain T3SS_needle_F PF09392.10 GAN06329.1 - 0.014 15.6 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF KdpA PF03814.15 GAN06329.1 - 0.093 10.9 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit PsbX PF06596.11 GAN06329.1 - 0.093 12.7 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Vps55 PF04133.14 GAN06329.1 - 0.097 12.6 0.3 0.15 12.0 0.3 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 55 DUF2838 PF10998.8 GAN06330.1 - 8.1e-42 142.0 8.1 8.1e-42 142.0 8.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) ApoC-I PF04691.12 GAN06330.1 - 0.0074 16.2 2.1 0.014 15.3 2.1 1.5 1 0 0 1 1 1 1 Apolipoprotein C-I (ApoC-1) OmpH PF03938.14 GAN06330.1 - 0.05 13.9 1.8 0.083 13.2 1.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HMW1C_N PF18071.1 GAN06330.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 HMW1C N-terminal Matrilin_ccoil PF10393.9 GAN06330.1 - 0.85 9.5 3.0 8.7 6.3 0.7 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Na_H_Exchanger PF00999.21 GAN06331.1 - 8.5e-69 232.2 36.8 1e-68 231.9 36.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TetR_C_33 PF13305.6 GAN06331.1 - 0.14 12.9 0.1 0.38 11.5 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CDC45 PF02724.14 GAN06331.1 - 0.2 9.9 3.5 0.3 9.3 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4199 PF13858.6 GAN06331.1 - 1.8 9.0 34.5 1.2 9.6 15.6 4.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) Tim17 PF02466.19 GAN06331.1 - 2 8.8 6.6 1.2 9.5 0.0 3.2 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family SH3_1 PF00018.28 GAN06333.1 - 5.4e-07 29.1 0.0 1.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN06333.1 - 9e-05 22.3 0.8 0.00032 20.5 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain RA PF00788.23 GAN06333.1 - 0.014 16.0 0.1 13 6.5 0.0 4.1 3 1 0 3 3 3 0 Ras association (RalGDS/AF-6) domain DUF1631 PF07793.11 GAN06334.1 - 0.81 8.0 3.4 0.83 8.0 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) NUDIX PF00293.28 GAN06335.1 - 8.1e-15 55.0 0.4 8.1e-15 55.0 0.4 1.7 2 0 0 2 2 2 1 NUDIX domain WD40 PF00400.32 GAN06336.1 - 1e-28 99.0 3.9 7e-08 33.0 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06336.1 - 4.1e-08 33.4 0.7 0.0015 18.8 0.2 4.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN06336.1 - 9.6e-06 25.1 0.0 0.00084 18.8 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 GAN06336.1 - 5.1e-05 22.4 0.9 0.58 9.0 0.3 3.1 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAN06336.1 - 0.00033 20.6 2.5 0.079 12.8 0.1 3.4 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 GAN06336.1 - 0.0019 18.0 1.2 0.0048 16.7 0.5 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.14 GAN06336.1 - 0.0043 16.2 0.2 2.4 7.1 0.0 2.8 1 1 1 3 3 3 2 Coatomer WD associated region Nup160 PF11715.8 GAN06336.1 - 0.067 11.8 1.6 0.29 9.7 0.3 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 RNA_polI_A14 PF08203.11 GAN06337.1 - 0.16 12.7 3.1 1.7 9.5 0.2 2.8 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DAGK_acc PF00609.19 GAN06338.1 - 3.5e-15 56.7 0.1 7e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 GAN06338.1 - 3e-12 46.3 0.0 2.4e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Y_phosphatase2 PF03162.13 GAN06339.1 - 8e-56 188.2 0.0 9.6e-56 187.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAN06339.1 - 2.7e-06 27.5 0.0 8.2e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAN06339.1 - 0.0042 16.9 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN06339.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Kelch_5 PF13854.6 GAN06340.1 - 4.1e-21 74.5 0.6 0.0011 18.8 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 GAN06340.1 - 1.4e-12 47.4 18.5 0.0015 18.7 1.5 5.6 4 1 2 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAN06340.1 - 6.3e-12 45.3 22.0 7.9e-06 25.8 0.0 5.7 5 2 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN06340.1 - 1.5e-09 37.9 1.0 0.0007 19.8 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN06340.1 - 0.025 14.5 14.2 0.89 9.6 0.0 5.1 5 1 0 5 5 5 0 Kelch motif Syndecan PF01034.20 GAN06340.1 - 0.58 10.1 1.8 1.4 8.9 1.8 1.6 1 0 0 1 1 1 0 Syndecan domain Arrestin_N PF00339.29 GAN06342.1 - 0.00014 22.0 0.2 0.00045 20.3 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain 2-Hacid_dh_C PF02826.19 GAN06343.1 - 2.7e-49 166.9 0.0 5e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAN06343.1 - 6.1e-37 126.3 0.0 8.2e-37 125.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAN06343.1 - 8.7e-05 22.7 1.4 0.00073 19.7 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 GAN06343.1 - 0.0011 18.7 0.0 0.0033 17.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 GAN06343.1 - 0.0089 16.1 0.4 0.022 14.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HMA PF00403.26 GAN06344.1 - 7.8e-15 55.1 0.7 1.2e-14 54.5 0.7 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain GlgX_C PF18390.1 GAN06344.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain Mito_carr PF00153.27 GAN06345.1 - 7.1e-49 163.7 6.7 5.3e-18 64.7 0.1 3.6 2 2 1 3 3 3 3 Mitochondrial carrier protein ThiS PF02597.20 GAN06345.1 - 5.3e-06 27.0 0.0 9.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 ThiS family Galactosyl_T PF01762.21 GAN06346.1 - 2.1e-16 60.4 0.0 3.1e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 GAN06346.1 - 1.2e-11 44.8 13.3 1.2e-11 44.8 13.3 2.0 1 1 1 2 2 2 1 N-glycosylation protein Glyco_transf_21 PF13506.6 GAN06346.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 LRR_4 PF12799.7 GAN06347.1 - 0.0005 20.4 9.2 4.5 7.8 0.2 6.9 4 3 6 10 10 10 1 Leucine Rich repeats (2 copies) FlhC PF05280.11 GAN06347.1 - 0.075 12.7 1.3 0.19 11.4 1.3 1.7 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Zn-ribbon_8 PF09723.10 GAN06347.1 - 0.11 12.7 1.8 0.4 10.8 1.8 2.0 1 0 0 1 1 1 0 Zinc ribbon domain LRR_1 PF00560.33 GAN06347.1 - 0.12 13.0 1.8 1.2e+02 3.8 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat zinc_ribbon_9 PF14369.6 GAN06347.1 - 0.43 10.9 3.1 3.4 8.0 3.2 2.4 1 1 1 2 2 2 0 zinc-ribbon DTHCT PF08070.11 GAN06347.1 - 7.3 7.4 13.8 1.3 9.8 6.3 2.5 2 1 0 2 2 2 0 DTHCT (NUC029) region Ribosomal_L7Ae PF01248.26 GAN06348.1 - 2.5e-28 97.7 2.1 3.1e-28 97.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1517 PF07466.11 GAN06348.1 - 0.045 13.9 0.2 0.049 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) PAC4 PF16093.5 GAN06349.1 - 3e-19 69.0 0.0 4.7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 RRM_1 PF00076.22 GAN06350.1 - 7.5e-27 93.0 0.0 2.2e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 GAN06350.1 - 1.4e-21 74.9 0.8 5.1e-05 22.7 0.0 5.2 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 GAN06350.1 - 2e-06 27.6 0.0 0.0045 16.8 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 GAN06350.1 - 0.0017 18.4 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif SET_assoc PF11767.8 GAN06350.1 - 0.01 15.4 0.0 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 GAN06350.1 - 0.029 14.5 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 Nab6_mRNP_bdg PF10567.9 GAN06350.1 - 1.5 8.2 0.0 1.5 8.2 0.0 3.4 4 0 0 4 4 4 0 RNA-recognition motif ATP-sulfurylase PF01747.17 GAN06352.1 - 3e-86 288.3 0.1 4.4e-86 287.8 0.1 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 GAN06352.1 - 3.4e-55 186.0 0.0 5.8e-55 185.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 GAN06352.1 - 5.6e-51 172.6 0.0 1e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 GAN06352.1 - 0.0025 18.4 0.0 0.0062 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAN06352.1 - 0.049 13.1 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAN06352.1 - 0.061 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 GAN06353.1 - 5.3e-17 61.7 0.4 5.3e-17 61.7 0.4 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain RhoGAP PF00620.27 GAN06354.1 - 3e-39 134.3 0.6 9.5e-39 132.7 0.6 1.8 1 0 0 1 1 1 1 RhoGAP domain MCM PF00493.23 GAN06355.1 - 8.9e-96 319.3 0.2 1.4e-95 318.6 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAN06355.1 - 4.4e-33 113.8 0.0 8.2e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAN06355.1 - 1e-22 80.3 2.5 2.5e-22 79.1 2.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAN06355.1 - 4.6e-17 62.5 0.0 1.7e-16 60.7 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAN06355.1 - 3.6e-08 33.1 0.1 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAN06355.1 - 0.00048 20.0 0.0 0.0049 16.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAN06355.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 GAN06355.1 - 0.026 14.5 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PDCD2_C PF04194.13 GAN06355.1 - 4.5 7.3 6.4 30 4.6 0.0 3.0 3 0 0 3 3 3 0 Programmed cell death protein 2, C-terminal putative domain Pkinase PF00069.25 GAN06356.1 - 5.9e-65 219.2 0.0 1.1e-64 218.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06356.1 - 1.7e-48 165.2 0.0 3e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 GAN06356.1 - 1.4e-08 35.0 0.0 3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 GAN06356.1 - 4.1e-07 29.6 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 GAN06356.1 - 0.00047 19.0 0.0 0.0011 17.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAN06356.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN06356.1 - 0.13 12.2 0.1 1.1 9.1 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN06356.1 - 1.3 7.8 4.0 0.25 10.2 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain RskA PF10099.9 GAN06357.1 - 0.013 15.8 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA zf-C2H2 PF00096.26 GAN06358.1 - 3.9e-11 42.7 12.0 3.2e-05 24.1 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN06358.1 - 1.3e-06 28.5 14.1 0.0012 19.2 0.9 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN06358.1 - 6.4e-06 26.6 10.8 0.0085 16.8 3.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN06358.1 - 0.0022 17.9 7.4 0.0043 17.0 1.5 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 GAN06358.1 - 0.0029 17.9 1.9 0.0055 17.0 1.9 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 GAN06358.1 - 0.0044 16.9 4.1 0.13 12.2 0.8 2.6 2 0 0 2 2 2 1 zinc-finger of a C2HC-type DUF3268 PF11672.8 GAN06358.1 - 0.036 14.4 0.2 0.059 13.7 0.2 1.2 1 0 0 1 1 1 0 zinc-finger-containing domain zf-BED PF02892.15 GAN06358.1 - 0.049 13.7 6.5 0.13 12.3 0.4 3.0 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 GAN06358.1 - 0.14 12.5 0.6 0.14 12.5 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 GAN06358.1 - 0.23 11.4 8.1 0.26 11.2 2.4 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-met PF12874.7 GAN06358.1 - 0.37 11.3 5.2 0.15 12.5 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 GAN06358.1 - 2 8.2 7.4 0.67 9.8 1.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type PDZ_1 PF12812.7 GAN06359.1 - 4.3e-33 113.2 0.0 1.5e-23 82.6 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 GAN06359.1 - 2.1e-19 70.9 0.1 2.5e-15 57.7 0.1 3.0 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 GAN06359.1 - 4.8e-16 58.3 0.1 5.6e-06 26.1 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 GAN06359.1 - 2e-14 53.7 0.3 0.00035 20.8 0.0 4.9 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 GAN06359.1 - 3.5e-13 49.7 1.6 0.00022 21.5 0.0 4.4 5 0 0 5 5 5 3 PDZ domain Tricorn_PDZ PF14685.6 GAN06359.1 - 0.00057 19.8 1.1 2 8.4 0.0 3.8 4 0 0 4 4 4 2 Tricorn protease PDZ domain Trypsin PF00089.26 GAN06359.1 - 0.0082 16.0 0.4 2.7 7.7 0.0 3.6 3 1 0 3 3 3 1 Trypsin PBP1_TM PF14812.6 GAN06359.1 - 0.03 14.7 3.1 0.058 13.8 3.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S46 PF10459.9 GAN06359.1 - 0.043 12.5 0.4 0.084 11.5 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 GRASP55_65 PF04495.14 GAN06359.1 - 0.052 13.9 0.1 0.86 9.9 0.0 2.6 3 0 0 3 3 3 0 GRASP55/65 PDZ-like domain Pkinase PF00069.25 GAN06360.1 - 2.7e-76 256.4 0.0 4.1e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Glyco_transf_10 PF00852.19 GAN06360.1 - 5.3e-46 156.6 1.7 9.7e-46 155.7 1.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Pkinase_Tyr PF07714.17 GAN06360.1 - 7.5e-36 123.7 0.0 1.3e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_tran_10_N PF17039.5 GAN06360.1 - 3.4e-16 59.7 0.9 3.4e-16 59.7 0.9 2.2 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Pkinase_fungal PF17667.1 GAN06360.1 - 7.3e-06 25.0 0.0 3.7e-05 22.7 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 GAN06360.1 - 4.7e-05 22.9 0.0 0.00011 21.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAN06360.1 - 0.0021 17.4 0.1 0.0091 15.4 0.0 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAN06360.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 GAN06360.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_trans_1_2 PF13524.6 GAN06360.1 - 0.15 12.5 0.0 1.6 9.2 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferases group 1 CPSase_L_D2 PF02786.17 GAN06361.1 - 3.8e-69 232.4 0.1 8e-69 231.3 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAN06361.1 - 3e-33 114.7 0.0 8e-33 113.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN06361.1 - 2e-31 108.3 0.0 5e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAN06361.1 - 4.9e-14 51.9 2.6 3.2e-13 49.3 1.9 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAN06361.1 - 5.1e-10 39.2 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 GAN06361.1 - 1e-07 31.7 0.3 5e-05 23.0 0.1 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 GAN06361.1 - 2.4e-07 30.9 0.0 4.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 GAN06361.1 - 2.4e-07 30.5 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 GAN06361.1 - 2.1e-06 28.4 1.5 0.0098 16.6 0.1 3.3 3 0 0 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.6 GAN06361.1 - 1.2e-05 25.2 1.3 0.0004 20.3 0.2 2.9 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 GAN06361.1 - 6.1e-05 22.3 0.6 0.0013 18.0 0.1 2.8 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 GAN06361.1 - 0.00011 21.8 0.1 0.00023 20.7 0.1 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_5 PF13549.6 GAN06361.1 - 0.0097 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 GAN06361.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon LAL_C2 PF18603.1 GAN06361.1 - 0.1 12.8 0.5 2.8 8.2 0.0 3.4 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 RFX5_DNA_bdg PF14621.6 GAN06361.1 - 0.1 12.4 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 RFX5 DNA-binding domain PASTA PF03793.19 GAN06361.1 - 0.5 10.3 4.0 49 3.9 0.0 4.1 6 0 0 6 6 5 0 PASTA domain WD40 PF00400.32 GAN06362.1 - 1.3e-17 63.8 17.6 0.00016 22.4 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06362.1 - 6.9e-10 39.1 7.9 0.0024 18.1 0.1 4.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain VCBS PF13517.6 GAN06362.1 - 0.0019 18.8 0.9 17 6.1 0.0 4.5 5 0 0 5 5 5 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ge1_WD40 PF16529.5 GAN06362.1 - 0.0026 16.8 2.7 4.5 6.1 0.1 3.8 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 GAN06362.1 - 0.0099 15.8 11.1 0.029 14.3 0.3 2.9 1 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term HepII_C PF18675.1 GAN06362.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Heparinase II C-terminal domain Y_phosphatase2 PF03162.13 GAN06363.1 - 7.3e-41 139.5 0.0 9e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAN06363.1 - 0.0041 17.1 0.0 0.0072 16.3 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAN06363.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PS_Dcarbxylase PF02666.15 GAN06364.1 - 8.2e-63 211.6 0.0 1.3e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 GAN06364.1 - 6.7e-31 106.6 0.1 2.5e-19 69.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain PRA1 PF03208.19 GAN06364.1 - 1.1e-25 90.0 1.2 2.2e-25 88.9 1.2 1.5 1 0 0 1 1 1 1 PRA1 family protein Nop14 PF04147.12 GAN06364.1 - 0.00035 18.9 12.5 0.00054 18.3 12.5 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GAN06364.1 - 0.0067 15.9 12.9 0.014 14.8 12.9 1.5 1 0 0 1 1 1 1 SDA1 Nop25 PF09805.9 GAN06364.1 - 0.015 15.8 7.8 0.047 14.2 6.6 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) UBZ_FAAP20 PF15750.5 GAN06364.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger DOCK-C2 PF14429.6 GAN06364.1 - 0.083 12.7 1.1 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins DUF4598 PF15370.6 GAN06364.1 - 0.11 13.0 9.6 0.38 11.2 9.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) BUD22 PF09073.10 GAN06364.1 - 0.13 11.6 12.5 0.3 10.4 12.5 1.5 1 0 0 1 1 1 0 BUD22 SGT1 PF07093.11 GAN06364.1 - 0.16 10.4 13.1 0.25 9.7 13.1 1.2 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 GAN06364.1 - 0.42 8.8 11.6 0.71 8.1 11.6 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GAN06364.1 - 1.9 7.7 21.4 3.5 6.9 21.4 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAN06364.1 - 5.2 6.7 19.5 13 5.4 19.5 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein tRNA-synt_2 PF00152.20 GAN06365.1 - 5.8e-80 268.7 0.3 7e-80 268.4 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAN06365.1 - 4.7e-05 23.3 3.0 0.0021 18.0 0.8 2.4 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAN06365.1 - 0.0036 16.8 0.4 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MFS_1 PF07690.16 GAN06366.1 - 4e-22 78.6 32.0 7.7e-22 77.7 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN06366.1 - 0.032 13.1 23.4 0.013 14.4 10.9 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter CarS-like PF01864.17 GAN06366.1 - 8.6 6.3 12.5 1.4 8.9 0.3 3.0 3 1 1 4 4 4 0 CDP-archaeol synthase Methyltransf_25 PF13649.6 GAN06367.1 - 1.4e-13 51.3 0.0 4.3e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN06367.1 - 8.5e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN06367.1 - 2.5e-11 44.1 0.0 9e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN06367.1 - 7.5e-10 38.8 0.0 3e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAN06367.1 - 4.6e-06 27.3 0.0 1.6e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN06367.1 - 1.1e-05 25.0 0.0 2.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 GAN06367.1 - 0.00042 19.7 0.0 0.0059 16.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 GAN06367.1 - 0.0009 18.8 0.0 0.025 14.0 0.0 2.3 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 GAN06367.1 - 0.0031 16.8 0.0 0.0089 15.3 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 GAN06367.1 - 0.0039 15.8 0.0 0.12 10.9 0.0 2.1 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 GAN06367.1 - 0.0073 15.9 0.1 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.12 GAN06367.1 - 0.033 14.0 0.0 0.099 12.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 GAN06367.1 - 0.051 12.5 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 GAN06367.1 - 0.063 12.7 0.1 0.48 9.8 0.1 2.1 1 1 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 GAN06367.1 - 0.21 11.2 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ASD2 PF08687.11 GAN06367.1 - 0.26 10.8 1.9 0.39 10.2 1.9 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 bZIP_2 PF07716.15 GAN06368.1 - 2.3e-11 43.6 8.3 2.5e-11 43.4 5.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN06368.1 - 2.6e-07 30.6 8.9 6.2e-07 29.4 6.7 2.4 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 GAN06368.1 - 3.6e-05 24.2 3.1 3.6e-05 24.2 3.1 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor DUF3450 PF11932.8 GAN06368.1 - 0.01 15.1 4.5 0.016 14.5 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 GAN06368.1 - 0.031 13.5 7.9 0.067 12.4 7.1 1.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 GAN06368.1 - 0.053 12.9 2.7 0.076 12.4 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 GAN06368.1 - 0.066 13.3 1.0 0.066 13.3 1.0 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 IFP_35_N PF07334.13 GAN06368.1 - 0.068 13.3 0.5 14 5.9 0.0 2.8 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Nup54 PF13874.6 GAN06368.1 - 0.15 12.1 6.7 0.28 11.3 6.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HalX PF08663.10 GAN06368.1 - 0.27 11.6 7.2 7.7 6.9 7.2 2.9 1 1 1 2 2 2 0 HalX domain Tropomyosin_1 PF12718.7 GAN06368.1 - 0.57 10.3 13.2 0.76 9.9 13.2 1.2 1 0 0 1 1 1 0 Tropomyosin like APG6_N PF17675.1 GAN06368.1 - 0.79 10.3 7.7 1.7 9.2 7.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region M PF02370.16 GAN06368.1 - 1.2 10.0 5.1 12 6.9 0.4 3.8 2 1 1 3 3 3 0 M protein repeat V_ATPase_I PF01496.19 GAN06368.1 - 7 4.4 5.8 8.3 4.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 GAN06368.1 - 7.4 6.4 10.1 0.34 10.7 0.6 2.4 1 1 1 2 2 2 0 Septum formation initiator US6 PF17616.2 GAN06370.1 - 0.27 11.2 1.7 0.63 10.0 1.7 1.6 1 0 0 1 1 1 0 Viral unique short region 6 Kei1 PF08552.11 GAN06370.1 - 0.36 10.7 16.5 4 7.3 16.5 2.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Endosulfine PF04667.17 GAN06371.1 - 8.3e-27 93.2 0.1 1.1e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region SPRY PF00622.28 GAN06372.1 - 1.9e-19 70.0 0.1 3.1e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Hva1_TUDOR PF11160.8 GAN06372.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain NlpE_C PF17185.4 GAN06373.1 - 0.14 12.5 1.0 0.97 9.8 1.0 2.5 1 0 0 1 1 1 0 NlpE C-terminal OB domain Ribosomal_60s PF00428.19 GAN06374.1 - 1.1e-20 74.0 3.4 1.7e-20 73.4 3.4 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein GTP1_OBG PF01018.22 GAN06375.1 - 5e-47 159.3 6.7 7.4e-31 106.8 5.1 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAN06375.1 - 1.2e-23 83.4 0.0 2.4e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN06375.1 - 3.5e-09 36.4 0.0 9.8e-09 34.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 GAN06375.1 - 5.1e-08 32.6 0.0 8.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN06375.1 - 3e-05 23.5 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_C PF08438.10 GAN06375.1 - 0.00022 21.7 0.6 0.00056 20.5 0.6 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal cobW PF02492.19 GAN06375.1 - 0.0064 16.1 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAN06375.1 - 0.014 15.9 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 GAN06375.1 - 0.028 13.4 0.1 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 GAN06375.1 - 0.042 13.3 0.3 0.15 11.5 0.3 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 GAN06375.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAN06375.1 - 0.058 12.9 0.2 5.4 6.5 0.2 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAN06375.1 - 0.064 13.3 2.3 4.9 7.2 0.0 2.8 2 1 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 GAN06375.1 - 0.066 13.1 0.0 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 GAN06375.1 - 0.069 13.7 0.7 1.4 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain SARAF PF06682.12 GAN06377.1 - 0.00049 19.9 0.7 0.00068 19.4 0.3 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF1180 PF06679.12 GAN06377.1 - 0.00082 19.8 2.2 0.00082 19.8 2.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) TMEM154 PF15102.6 GAN06377.1 - 0.0046 16.9 8.8 0.07 13.0 7.8 2.4 1 1 0 1 1 1 1 TMEM154 protein family DUF2070 PF09843.9 GAN06377.1 - 0.0063 14.9 0.3 0.0082 14.5 0.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF4834 PF16118.5 GAN06377.1 - 0.02 15.9 0.0 0.02 15.9 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) RCR PF12273.8 GAN06377.1 - 0.023 15.3 0.4 0.023 15.3 0.4 2.1 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DHHC PF01529.20 GAN06377.1 - 0.026 14.6 0.3 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase TraE PF05309.11 GAN06377.1 - 0.04 13.3 0.1 0.04 13.3 0.1 2.1 2 0 0 2 2 2 0 TraE protein DUF5305 PF17231.2 GAN06377.1 - 0.059 12.8 0.4 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 GAN06377.1 - 0.063 12.0 0.1 0.13 11.0 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ctr PF04145.15 GAN06377.1 - 0.1 13.2 0.3 0.46 11.1 0.0 2.0 1 1 1 2 2 2 0 Ctr copper transporter family DUF3169 PF11368.8 GAN06377.1 - 0.12 11.9 1.7 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) CcmD PF04995.14 GAN06377.1 - 0.16 12.1 0.1 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) EVI2A PF05399.11 GAN06377.1 - 0.19 11.3 12.1 0.0091 15.6 6.3 1.6 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) HemY_N PF07219.13 GAN06377.1 - 0.22 11.7 1.2 0.36 11.0 0.1 1.9 2 0 0 2 2 2 0 HemY protein N-terminus Baculo_11_kDa PF06143.11 GAN06377.1 - 0.34 10.5 2.9 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family Sar8_2 PF03058.14 GAN06377.1 - 1.7 9.2 4.7 4.3 7.9 4.7 1.6 1 0 0 1 1 1 0 Sar8.2 family WBP-1 PF11669.8 GAN06377.1 - 5.1 7.8 7.3 78 4.0 0.0 2.5 2 1 0 2 2 2 0 WW domain-binding protein 1 DUF2254 PF10011.9 GAN06377.1 - 10 4.9 10.5 22 3.7 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Ribosomal_60s PF00428.19 GAN06378.1 - 9.3e-26 90.2 4.9 1.1e-25 90.0 4.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CHCH PF06747.13 GAN06379.1 - 5.8e-06 26.3 11.0 1.1e-05 25.5 11.0 1.5 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 GAN06379.1 - 0.003 17.8 3.7 0.004 17.3 3.7 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 GAN06379.1 - 0.0092 16.3 6.0 0.012 15.8 6.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 TAP_C PF03943.13 GAN06379.1 - 0.0099 15.5 0.9 0.014 15.0 0.9 1.3 1 0 0 1 1 1 1 TAP C-terminal domain WD40 PF00400.32 GAN06380.1 - 1.6e-56 186.9 18.9 1.3e-06 29.0 0.2 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06380.1 - 3e-21 75.5 4.0 0.008 16.5 0.0 8.4 4 3 5 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 GAN06380.1 - 4e-21 75.3 0.3 7.7e-21 74.4 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 GAN06380.1 - 3.7e-07 29.8 0.0 1.6 8.0 0.1 5.0 5 0 0 5 5 5 3 WD40-like domain Utp13 PF08625.11 GAN06380.1 - 0.062 13.2 0.1 0.062 13.2 0.1 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Pkinase PF00069.25 GAN06381.1 - 3e-58 197.3 0.0 4.5e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06381.1 - 8.8e-29 100.6 0.0 2e-28 99.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN06381.1 - 0.0071 15.2 0.0 0.018 13.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 GAN06381.1 - 0.033 13.8 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 GAN06381.1 - 0.061 13.2 0.1 10 6.0 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN06381.1 - 0.071 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRAL_TRIO PF00650.20 GAN06382.1 - 2.2e-42 144.5 0.1 4.8e-42 143.4 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAN06382.1 - 5.8e-08 33.0 0.0 9.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN06382.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UvrD-helicase PF00580.21 GAN06383.1 - 1.8e-64 218.2 9.1 1.8e-64 218.2 9.1 3.3 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 GAN06383.1 - 4e-53 181.0 2.2 4e-53 181.0 2.2 3.3 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GAN06383.1 - 1.6e-33 116.1 1.4 1.8e-33 115.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 GAN06383.1 - 1.1e-10 41.1 0.1 1e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 GAN06383.1 - 1e-07 31.9 0.0 0.00092 19.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain SPOUT_MTase_2 PF14419.6 GAN06383.1 - 0.0071 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP Terminase_6 PF03237.15 GAN06383.1 - 0.022 14.4 0.2 0.08 12.6 0.0 2.1 2 0 0 2 2 2 0 Terminase-like family Choline_kinase PF01633.20 GAN06384.1 - 4.4e-66 222.5 0.0 5.9e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAN06384.1 - 1.9e-12 47.7 0.0 2.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ResIII PF04851.15 GAN06385.1 - 2e-23 83.3 0.0 3.1e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN06385.1 - 1.2e-11 44.9 0.0 1.8e-10 41.2 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN06385.1 - 2.8e-10 40.2 0.0 4.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAN06385.1 - 6.3e-10 39.1 0.0 8.2e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase T2SSE PF00437.20 GAN06385.1 - 0.0021 17.2 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 GAN06385.1 - 0.009 15.3 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 GAN06385.1 - 0.03 13.0 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain GIT_SHD PF08518.11 GAN06385.1 - 0.1 12.2 0.1 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT DHHC PF01529.20 GAN06386.1 - 1.4e-34 119.1 8.1 1.4e-34 119.1 8.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM72 PF16054.5 GAN06386.1 - 0.013 15.2 1.6 0.031 14.0 1.6 1.7 1 0 0 1 1 1 0 Transmembrane protein family 72 Tom7 PF08038.12 GAN06386.1 - 0.11 12.1 2.1 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 TOM7 family FA_desaturase PF00487.24 GAN06386.1 - 0.14 12.0 3.0 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Fatty acid desaturase Mito_carr PF00153.27 GAN06388.1 - 2.7e-55 184.3 9.8 5.7e-21 74.2 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN06388.1 - 3.1e-06 26.5 3.4 0.023 13.8 0.2 3.1 3 0 0 3 3 3 3 Gammaproteobacterial serine protease DUF5518 PF17647.1 GAN06388.1 - 0.0075 16.4 5.3 0.88 9.7 1.1 3.4 3 0 0 3 3 3 2 Family of unknown function (DUF5518) NAD_binding_4 PF07993.12 GAN06389.1 - 0.022 14.0 0.0 0.23 10.6 0.0 2.0 1 1 1 2 2 2 0 Male sterility protein Epimerase PF01370.21 GAN06389.1 - 0.025 14.0 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAN06389.1 - 0.094 12.6 0.1 0.14 12.0 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding DUF4460 PF14687.6 GAN06390.1 - 9e-08 32.1 0.3 9e-08 32.1 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) RabGAP-TBC PF00566.18 GAN06393.1 - 5.9e-53 179.7 0.7 1.3e-51 175.4 0.1 2.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 GAN06393.1 - 1e-28 99.5 3.6 3.5e-16 59.1 0.2 2.5 2 0 0 2 2 2 2 GRAM domain Peptidase_M16_C PF05193.21 GAN06395.1 - 4e-49 167.1 0.0 7e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAN06395.1 - 1.2e-41 142.2 0.0 1e-40 139.2 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TRPM_tetra PF16519.5 GAN06395.1 - 0.14 12.2 1.0 0.57 10.3 0.5 2.1 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Gal4_dimer PF03902.13 GAN06395.1 - 0.16 12.1 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF2564 PF10819.8 GAN06395.1 - 0.17 12.3 0.6 2.2 8.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) EMG1 PF03587.14 GAN06396.1 - 4.2e-41 140.8 0.0 4.5e-38 130.9 0.0 2.0 1 1 1 2 2 2 2 EMG1/NEP1 methyltransferase NUDIX PF00293.28 GAN06397.1 - 3.5e-06 27.1 0.1 4.6e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 GAN06398.1 - 6.9e-11 42.3 0.1 8.8e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 GAN06398.1 - 0.0038 16.8 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase FHA_2 PF17913.1 GAN06399.1 - 1.2e-06 28.7 0.0 3.4e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain FHA PF00498.26 GAN06399.1 - 2.2e-06 27.9 0.2 7.5e-06 26.2 0.2 1.9 1 0 0 1 1 1 1 FHA domain Forkhead PF00250.18 GAN06399.1 - 0.00035 20.8 0.1 0.0028 17.9 0.0 2.4 2 0 0 2 2 2 1 Forkhead domain Vip3A_N PF12495.8 GAN06399.1 - 0.065 13.1 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal GMC_oxred_N PF00732.19 GAN06400.1 - 9.4e-53 179.5 0.3 1.5e-52 178.8 0.3 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAN06400.1 - 2.3e-22 80.1 0.0 4.3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAN06400.1 - 3.7e-10 39.5 4.1 3.6e-05 23.0 3.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAN06400.1 - 1.3e-06 27.9 2.7 0.00035 19.9 0.3 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN06400.1 - 4.3e-06 25.7 2.6 0.005 15.6 1.2 2.4 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 GAN06400.1 - 7.1e-06 25.8 4.4 0.019 14.6 1.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN06400.1 - 0.00025 21.2 2.0 0.00068 19.8 2.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAN06400.1 - 0.00094 18.5 0.3 0.0014 17.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAN06400.1 - 0.003 16.6 0.8 0.085 11.9 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.16 GAN06400.1 - 0.0039 16.8 0.7 0.0091 15.7 0.1 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 GAN06400.1 - 0.0069 15.7 2.2 0.26 10.5 0.9 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAN06400.1 - 0.0074 15.6 2.6 0.036 13.3 0.3 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 GAN06400.1 - 0.0094 15.1 2.8 0.37 9.8 0.7 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Cohesin_load PF10345.9 GAN06400.1 - 0.06 11.8 0.1 0.081 11.3 0.1 1.1 1 0 0 1 1 1 0 Cohesin loading factor GDI PF00996.18 GAN06400.1 - 0.28 9.7 1.0 0.42 9.1 0.1 1.7 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.27 GAN06400.1 - 0.37 11.4 5.5 0.52 10.9 1.1 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN06400.1 - 0.49 9.7 9.0 0.069 12.5 4.4 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ras PF00071.22 GAN06401.1 - 4.8e-46 156.3 0.1 8e-46 155.6 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN06401.1 - 6.3e-16 58.7 0.0 1.6e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN06401.1 - 2.6e-08 33.5 0.0 5.8e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN06401.1 - 4.3e-06 26.4 0.0 1.8e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAN06401.1 - 8.3e-06 25.4 0.0 2.9e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF676 PF05057.14 GAN06401.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) MMR_HSR1 PF01926.23 GAN06401.1 - 0.00026 21.0 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN06401.1 - 0.0003 20.8 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase PGAP1 PF07819.13 GAN06401.1 - 0.00038 20.2 0.2 0.0012 18.6 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein AAA_14 PF13173.6 GAN06401.1 - 0.0087 16.1 0.0 0.052 13.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain SRPRB PF09439.10 GAN06401.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Hydrolase_4 PF12146.8 GAN06401.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 GAN06401.1 - 0.047 12.8 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 GAN06401.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 GAN06401.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 GAN06401.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_16 PF13191.6 GAN06401.1 - 0.17 12.3 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain CDC37_N PF03234.14 GAN06403.1 - 3.4e-36 125.0 3.1 3.4e-36 125.0 3.1 3.0 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 GAN06403.1 - 9.1e-34 115.9 1.5 2.2e-33 114.7 0.1 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 GAN06403.1 - 2e-18 66.4 0.3 2e-18 66.4 0.3 4.0 4 1 0 4 4 4 1 Cdc37 C terminal domain GP41 PF00517.17 GAN06403.1 - 0.065 13.1 0.8 0.14 12.1 0.8 1.5 1 1 0 1 1 1 0 Retroviral envelope protein CHASE3 PF05227.13 GAN06403.1 - 0.22 11.4 4.6 0.27 11.2 0.8 2.7 2 1 1 3 3 3 0 CHASE3 domain KxDL PF10241.9 GAN06403.1 - 0.23 11.8 7.0 1.7 9.0 0.4 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein NPV_P10 PF05531.12 GAN06403.1 - 1.4 9.5 7.9 6 7.4 1.5 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAN06403.1 - 1.4 8.9 5.5 2.4 8.2 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PPR_2 PF13041.6 GAN06404.1 - 1.7e-28 98.5 5.5 1.1e-12 48.0 0.0 7.0 4 2 3 7 7 7 5 PPR repeat family PPR_3 PF13812.6 GAN06404.1 - 4.7e-23 81.0 4.8 0.00046 20.2 0.0 6.9 5 2 3 8 8 8 7 Pentatricopeptide repeat domain PPR PF01535.20 GAN06404.1 - 3.8e-15 55.0 17.4 0.00096 19.2 0.4 8.0 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 GAN06404.1 - 2.1e-13 50.1 0.0 5.5e-09 35.7 0.0 3.3 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAN06404.1 - 3.6e-13 49.0 11.2 0.00011 21.8 0.0 6.6 7 0 0 7 7 7 4 PPR repeat ATP13 PF12921.7 GAN06404.1 - 0.00011 22.0 0.6 0.0059 16.5 0.1 3.1 3 0 0 3 3 3 1 Mitochondrial ATPase expression RPM2 PF08579.11 GAN06404.1 - 0.0051 17.2 7.1 0.58 10.6 0.4 4.3 3 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 GAN06404.1 - 0.028 15.2 0.0 41 5.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NAD_Gly3P_dh_N PF01210.23 GAN06406.1 - 2.2e-51 173.9 0.1 1.1e-50 171.7 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 GAN06406.1 - 4.9e-49 166.3 0.2 1.2e-48 165.0 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 GAN06406.1 - 0.00037 21.0 0.0 1.3 9.6 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAN06406.1 - 0.13 12.7 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain VHS PF00790.19 GAN06407.1 - 1.2e-15 57.7 0.7 2.1e-15 56.8 0.7 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAN06407.1 - 0.047 14.0 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 GAT domain Peptidase_M61 PF05299.12 GAN06407.1 - 0.15 12.4 0.5 0.92 9.9 0.0 2.5 3 0 0 3 3 3 0 M61 glycyl aminopeptidase TRAPPC-Trs85 PF12739.7 GAN06408.1 - 3.3e-123 411.7 0.2 4.6e-123 411.2 0.2 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 GAN06408.1 - 0.046 13.8 0.3 0.74 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 GAN06408.1 - 0.1 12.0 1.1 0.48 9.8 0.2 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Pkinase PF00069.25 GAN06410.1 - 3.5e-69 233.1 0.0 9.9e-69 231.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06410.1 - 4.5e-43 147.4 0.0 1.3e-42 145.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN06410.1 - 6e-06 26.3 0.0 0.004 17.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN06410.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN06410.1 - 0.00022 20.6 0.1 0.00048 19.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN06410.1 - 0.001 18.1 0.1 0.001 18.1 0.1 2.5 2 1 0 2 2 2 1 Haspin like kinase domain EcKinase PF02958.20 GAN06410.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 GAN06410.1 - 0.017 14.7 1.2 0.03 13.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 GAN06410.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Acetyltransf_CG PF14542.6 GAN06411.1 - 1.5e-15 57.1 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 GAN06411.1 - 0.0024 18.1 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 GAN06411.1 - 0.039 13.4 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Pkinase PF00069.25 GAN06412.1 - 3e-46 157.9 0.9 1.8e-45 155.4 0.1 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06412.1 - 7.3e-25 87.7 0.1 1.3e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAN06412.1 - 0.0011 18.3 0.2 0.0026 17.1 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN06412.1 - 0.081 11.9 0.2 0.22 10.4 0.1 1.9 2 1 0 2 2 2 0 Haspin like kinase domain Bac_surface_Ag PF01103.23 GAN06413.1 - 7.4e-46 157.1 1.6 9.2e-46 156.8 1.6 1.1 1 0 0 1 1 1 1 Surface antigen DUF4364 PF14277.6 GAN06413.1 - 0.072 12.8 0.5 0.12 12.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) ATP-synt_ab PF00006.25 GAN06414.1 - 3.2e-11 43.3 0.0 5.1e-11 42.6 0.0 1.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAN06414.1 - 3.2e-06 27.5 0.1 4e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 GAN06415.1 - 5e-05 23.7 0.0 7.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Actin PF00022.19 GAN06416.1 - 1.9e-115 385.7 0.0 1.5e-114 382.8 0.0 1.9 1 1 0 1 1 1 1 Actin Methyltransf_5 PF01795.19 GAN06417.1 - 2.6e-86 289.9 0.8 2e-74 250.9 0.0 3.0 1 1 1 2 2 2 2 MraW methylase family Methyltransf_31 PF13847.6 GAN06417.1 - 7.6e-05 22.6 0.1 0.095 12.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GAN06417.1 - 0.039 14.7 0.0 0.19 12.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Nop53 PF07767.11 GAN06418.1 - 0.022 14.1 6.8 0.028 13.8 6.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 GAN06419.1 - 6.1e-66 222.5 0.0 1.1e-65 221.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06419.1 - 3.2e-30 105.3 0.0 1.2e-21 77.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN06419.1 - 1.6e-07 31.0 0.4 0.11 11.8 0.1 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 GAN06419.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAN06419.1 - 0.071 11.9 0.0 0.15 10.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase SH3_9 PF14604.6 GAN06420.1 - 1.4e-09 37.7 0.0 2.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN06420.1 - 3.2e-06 26.6 0.0 6.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN06420.1 - 0.003 17.2 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 GAN06420.1 - 0.032 14.4 0.3 0.19 11.8 0.0 2.3 3 0 0 3 3 3 0 Podoplanin TraL PF07178.11 GAN06420.1 - 0.14 12.6 0.6 0.32 11.5 0.6 1.5 1 0 0 1 1 1 0 TraL protein Pkinase PF00069.25 GAN06421.1 - 4.6e-38 131.1 7.8 5.6e-13 48.9 0.0 4.6 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06421.1 - 9e-20 71.0 0.0 3.6e-07 29.7 0.0 3.9 3 1 0 3 3 3 3 Protein tyrosine kinase TMEM252 PF15664.5 GAN06421.1 - 0.03 14.0 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Transmembrane protein 252 family LcrG PF07216.12 GAN06421.1 - 0.056 13.4 1.5 11 6.0 2.2 3.2 2 0 0 2 2 2 0 LcrG protein DUF2848 PF11010.8 GAN06422.1 - 0.0022 17.6 0.0 0.24 11.0 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF2848) Glyco_hydro_31 PF01055.26 GAN06423.1 - 5.1e-137 457.7 9.1 9.3e-137 456.8 9.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAN06423.1 - 4.2e-23 81.4 0.1 1.2e-22 79.9 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 GAN06423.1 - 2e-05 24.8 0.1 7.1e-05 23.0 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Complex1_LYR PF05347.15 GAN06424.1 - 1.7e-13 50.4 0.0 2.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 GAN06424.1 - 0.018 15.6 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR_2 PF13233.6 GAN06424.1 - 0.077 13.7 0.1 0.14 12.9 0.0 1.4 2 0 0 2 2 2 0 Complex1_LYR-like Ribosomal_S17 PF00366.20 GAN06425.1 - 4.3e-29 100.4 2.9 5e-29 100.2 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF1666 PF07891.12 GAN06425.1 - 0.057 13.1 0.1 0.061 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) PCB_OB PF17092.5 GAN06425.1 - 0.072 13.8 0.0 0.087 13.6 0.0 1.1 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain Glutaredoxin PF00462.24 GAN06426.1 - 1.1e-32 112.0 0.0 7.9e-16 58.0 0.0 2.8 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 GAN06426.1 - 3.2e-18 65.6 0.0 8.4e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 GAN06426.1 - 1.4e-06 27.5 0.0 4.1e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Phosducin Thioredoxin_8 PF13905.6 GAN06426.1 - 0.00019 21.7 0.2 0.05 13.9 0.0 3.3 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAN06426.1 - 0.00089 19.7 0.4 0.051 14.0 0.1 3.3 3 2 1 4 4 4 1 Thioredoxin-like domain RdRP PF05183.12 GAN06426.1 - 0.0012 17.6 0.0 0.61 8.7 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase HyaE PF07449.11 GAN06426.1 - 0.0018 18.2 0.1 0.038 14.0 0.0 3.0 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE SH3BGR PF04908.15 GAN06426.1 - 0.0087 16.2 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein zf-LITAF-like PF10601.9 GAN06427.1 - 1.2e-18 67.1 5.0 1.7e-18 66.6 5.0 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ACC PF17848.1 GAN06427.1 - 0.019 15.0 2.4 0.42 10.7 0.1 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Cys_rich_CPXG PF14255.6 GAN06427.1 - 0.021 14.7 3.0 0.78 9.7 0.8 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-RING_7 PF02591.15 GAN06427.1 - 0.031 14.5 1.7 0.43 10.8 0.1 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 GAN06427.1 - 0.045 13.2 1.5 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 GAN06427.1 - 0.049 13.6 0.4 10 6.2 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Sgf11 PF08209.11 GAN06427.1 - 0.05 13.2 1.2 6.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) UPF0547 PF10571.9 GAN06427.1 - 0.095 12.8 2.5 2.5 8.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ogr_Delta PF04606.12 GAN06427.1 - 0.29 11.2 4.3 1.7 8.7 0.4 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_4 PF13717.6 GAN06427.1 - 0.75 9.8 3.7 2.9 7.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF4211 PF13926.6 GAN06428.1 - 1.4e-18 67.4 0.4 5.5e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) CotH PF08757.11 GAN06429.1 - 6.3e-35 121.2 0.0 2.1e-34 119.5 0.0 1.8 2 1 0 2 2 2 1 CotH kinase protein Glyco_hydro_47 PF01532.20 GAN06430.1 - 3.8e-147 490.9 2.9 6.4e-147 490.2 2.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pox_VLTF3 PF04947.14 GAN06430.1 - 0.04 13.7 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Pkinase PF00069.25 GAN06431.1 - 4.2e-66 223.0 0.0 1.2e-65 221.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06431.1 - 3.6e-46 157.5 0.0 7.4e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN06431.1 - 2.8e-07 30.1 0.0 9.2e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAN06431.1 - 1.7e-06 27.1 0.6 1.2e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 GAN06431.1 - 0.0031 17.2 0.0 0.0079 15.8 0.0 1.7 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAN06431.1 - 0.0044 16.0 0.1 0.032 13.2 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAN06431.1 - 0.026 14.4 0.0 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN06431.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2489 PF10675.9 GAN06431.1 - 0.099 12.6 1.3 0.36 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) PTPlike_phytase PF14566.6 GAN06432.1 - 1e-137 454.5 0.6 2e-47 161.2 0.1 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 GAN06432.1 - 2.1e-06 27.6 0.3 0.32 10.8 0.0 4.0 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN06432.1 - 0.001 18.7 0.0 5.1 6.6 0.0 3.5 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAN06432.1 - 0.0063 16.5 0.0 0.81 9.6 0.0 2.9 2 0 0 2 2 2 1 Tyrosine phosphatase family EcoEI_R_C PF08463.10 GAN06432.1 - 0.012 15.7 1.2 0.063 13.4 0.0 2.8 4 0 0 4 4 4 0 EcoEI R protein C-terminal DUF2423 PF10338.9 GAN06432.1 - 0.039 14.2 1.5 4 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) SDF PF00375.18 GAN06433.1 - 3.1e-100 336.0 34.8 3.5e-100 335.8 34.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family RskA PF10099.9 GAN06434.1 - 3.4 7.9 0.0 3.4 7.9 0.0 4.7 4 1 1 5 5 5 0 Anti-sigma-K factor rskA Caldesmon PF02029.15 GAN06434.1 - 4.6 5.9 36.7 1.7 7.3 5.8 2.2 2 0 0 2 2 2 0 Caldesmon adh_short_C2 PF13561.6 GAN06435.1 - 8.4e-65 218.6 0.8 1e-64 218.3 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN06435.1 - 1.3e-52 178.2 3.0 2.1e-52 177.5 3.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN06435.1 - 3.3e-15 56.4 0.4 4.4e-15 56.1 0.4 1.1 1 0 0 1 1 1 1 KR domain Glyco_hydro_1 PF00232.18 GAN06435.1 - 0.0022 16.5 0.0 0.0029 16.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Polysacc_synt_2 PF02719.15 GAN06435.1 - 0.016 14.4 0.5 0.02 14.1 0.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.15 GAN06435.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Vps5 PF09325.10 GAN06436.1 - 3.3e-16 59.6 11.3 7.1e-10 38.8 4.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like PX PF00787.24 GAN06436.1 - 2.7e-13 49.9 0.2 1.2e-12 47.8 0.1 2.2 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 GAN06436.1 - 4.1e-05 23.4 7.4 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 1 BAR domain of APPL family Sec34 PF04136.15 GAN06436.1 - 0.00049 20.0 4.7 0.00049 20.0 4.7 2.0 2 0 0 2 2 2 1 Sec34-like family GrpE PF01025.19 GAN06436.1 - 0.0037 16.9 10.2 0.0043 16.7 0.2 2.7 2 1 0 2 2 2 1 GrpE Spidroin_N PF16763.5 GAN06436.1 - 0.0073 16.3 1.3 0.026 14.5 1.2 2.0 1 1 1 2 2 2 1 Major ampullate spidroin 1, spider silk protein 1, N-term DUF724 PF05266.14 GAN06436.1 - 0.012 15.4 1.7 0.012 15.4 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AdoHcyase PF05221.17 GAN06436.1 - 0.032 13.4 0.0 0.066 12.4 0.0 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase TPD52 PF04201.15 GAN06436.1 - 0.045 13.4 0.7 0.11 12.0 0.7 1.6 1 0 0 1 1 1 0 Tumour protein D52 family Occludin_ELL PF07303.13 GAN06436.1 - 0.077 13.7 7.9 0.16 12.7 0.2 3.3 2 1 1 3 3 3 0 Occludin homology domain Baculo_PEP_C PF04513.12 GAN06436.1 - 0.12 12.4 4.3 0.14 12.2 2.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.6 GAN06436.1 - 0.18 12.3 0.4 14 6.2 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) WD40_alt PF14077.6 GAN06436.1 - 0.51 10.2 2.1 23 5.0 0.1 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif CC2-LZ PF16516.5 GAN06436.1 - 1.4 9.4 8.1 1.3 9.5 0.5 3.1 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FapA PF03961.13 GAN06436.1 - 1.8 7.1 6.0 0.64 8.6 1.7 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A BLOC1_2 PF10046.9 GAN06436.1 - 1.9 8.9 9.2 1 9.7 0.9 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 GAN06436.1 - 2.6 8.3 5.3 12 6.2 0.5 2.6 2 0 0 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 GAN06436.1 - 7.4 5.4 9.8 4.1 6.2 6.2 1.9 1 1 1 2 2 2 0 LMBR1-like membrane protein TMF_TATA_bd PF12325.8 GAN06436.1 - 7.7 6.8 10.2 1.1 9.5 3.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4834 PF16118.5 GAN06437.1 - 0.1 13.6 0.1 0.21 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Cyclin PF08613.11 GAN06437.1 - 0.15 12.4 2.4 0.26 11.7 2.4 1.4 1 0 0 1 1 1 0 Cyclin Peptidase_C12 PF01088.21 GAN06438.1 - 5.5e-54 183.1 0.1 6.5e-54 182.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CABS1 PF15367.6 GAN06438.1 - 0.042 13.0 0.1 0.057 12.5 0.1 1.2 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 SUZ PF12752.7 GAN06439.1 - 1.7e-15 57.5 6.0 1.7e-15 57.5 6.0 3.1 2 1 1 3 3 3 1 SUZ domain R3H PF01424.22 GAN06439.1 - 1.2e-10 41.3 0.5 2.9e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 R3H domain AA_permease PF00324.21 GAN06440.1 - 9e-139 463.1 40.8 1.1e-138 462.8 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN06440.1 - 3.5e-45 154.6 44.1 4.3e-45 154.3 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease PrkA PF06798.12 GAN06440.1 - 0.006 16.2 0.4 0.0092 15.6 0.4 1.2 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain DUF2207 PF09972.9 GAN06440.1 - 7.2 5.2 0.0 7.2 5.2 0.0 4.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Mso1_Sec1_bdg PF14475.6 GAN06442.1 - 1.1e-06 28.1 0.2 5e-06 26.0 0.2 2.2 1 0 0 1 1 1 1 Sec1-binding region of Mso1 ADIP PF11559.8 GAN06443.1 - 6.9e-21 74.9 15.1 6.9e-21 74.9 15.1 3.9 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding Ribosomal_S28e PF01200.18 GAN06444.1 - 5e-33 112.9 1.3 7.1e-33 112.4 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S28e DUF2838 PF10998.8 GAN06445.1 - 1.3e-41 141.3 9.6 1.3e-41 141.3 9.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DUF1582 PF07621.11 GAN06446.1 - 0.01 15.7 3.7 12 5.9 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1582) PK_C PF02887.16 GAN06446.1 - 0.069 13.4 0.8 0.076 13.2 0.8 1.1 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain DUF3136 PF11334.8 GAN06446.1 - 2.8 7.8 6.3 8 6.3 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3136) Cation_efflux PF01545.21 GAN06447.1 - 1.9e-52 177.9 13.5 2.8e-52 177.4 13.5 1.3 1 0 0 1 1 1 1 Cation efflux family Pyridoxal_deC PF00282.19 GAN06448.1 - 1.1e-79 267.9 0.0 1.5e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAN06448.1 - 1.1e-05 24.6 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Kinesin PF00225.23 GAN06449.1 - 4.9e-99 331.4 6.6 4.9e-99 331.4 6.6 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN06449.1 - 6.5e-23 81.3 0.3 2.2e-22 79.6 0.3 2.0 1 0 0 1 1 1 1 Microtubule binding DUF1943 PF09172.11 GAN06449.1 - 0.078 12.2 11.1 0.054 12.7 6.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) HIT PF01230.23 GAN06450.1 - 9.6e-14 51.9 0.0 8.6e-13 48.9 0.0 2.6 3 0 0 3 3 3 1 HIT domain PH PF00169.29 GAN06450.1 - 3.4e-05 24.3 0.0 9e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 PH domain DcpS_C PF11969.8 GAN06450.1 - 0.00024 21.5 0.0 0.00067 20.1 0.0 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.29 GAN06451.1 - 2.2e-97 322.5 0.0 1.2e-47 161.6 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN06451.1 - 7.9e-29 99.2 5.9 1.1e-13 50.8 0.9 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GAN06451.1 - 2.6e-17 62.8 0.8 8.6e-17 61.1 0.7 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GAN06451.1 - 8.1e-14 51.7 0.0 1.9e-05 24.5 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAN06451.1 - 3.9e-13 49.9 0.0 3e-07 30.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAN06451.1 - 9.2e-12 45.3 0.0 7.3e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 GAN06451.1 - 5.4e-11 42.1 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 GAN06451.1 - 6.5e-11 42.4 0.6 3.5e-05 23.8 0.1 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN06451.1 - 8.3e-11 42.6 0.2 0.001 19.5 0.0 4.5 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.13 GAN06451.1 - 2.2e-09 37.0 0.1 0.001 18.3 0.0 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 GAN06451.1 - 4.3e-09 36.8 0.1 0.043 14.1 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAN06451.1 - 1.7e-07 31.8 0.0 0.022 15.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAN06451.1 - 2.5e-07 30.3 0.2 0.021 14.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAN06451.1 - 4.3e-07 29.8 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 GAN06451.1 - 2.4e-06 27.9 0.0 0.02 15.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 GAN06451.1 - 2.6e-06 28.0 0.0 0.041 14.4 0.0 3.8 3 1 0 3 3 2 2 ABC transporter AAA_7 PF12775.7 GAN06451.1 - 3.7e-06 26.6 0.0 0.02 14.4 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 GAN06451.1 - 5.1e-06 26.6 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 GAN06451.1 - 5.8e-06 25.6 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 GAN06451.1 - 7.1e-06 25.8 0.0 0.3 10.8 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 GAN06451.1 - 7.8e-06 26.2 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 GAN06451.1 - 1e-05 25.5 0.1 0.00032 20.6 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 GAN06451.1 - 1.7e-05 24.7 0.2 0.49 10.1 0.0 3.5 3 1 0 3 3 3 2 AAA domain ATPase PF06745.13 GAN06451.1 - 2.5e-05 23.8 0.3 1.1 8.5 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 GAN06451.1 - 3e-05 23.7 1.6 1.3 8.6 0.0 3.8 3 1 1 4 4 3 2 AAA domain DUF815 PF05673.13 GAN06451.1 - 5.9e-05 22.4 0.0 0.014 14.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 GAN06451.1 - 8.7e-05 22.5 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 GAN06451.1 - 0.00015 22.2 0.2 0.81 10.1 0.0 3.4 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 GAN06451.1 - 0.00017 21.1 1.5 0.49 9.8 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein TsaE PF02367.17 GAN06451.1 - 0.00023 21.2 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 GAN06451.1 - 0.00023 20.5 0.0 0.49 9.6 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GAN06451.1 - 0.00025 21.1 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 GAN06451.1 - 0.00034 20.5 0.0 0.94 9.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GAN06451.1 - 0.00091 19.1 0.2 1.1 8.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 GAN06451.1 - 0.0016 17.7 0.0 2.4 7.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.6 GAN06451.1 - 0.0028 18.0 1.6 3.5 8.0 0.0 3.4 3 1 1 4 4 3 1 AAA domain ATPase_2 PF01637.18 GAN06451.1 - 0.003 17.5 0.1 4.8 7.0 0.0 3.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAN06451.1 - 0.0046 16.9 0.1 1.1 9.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 GAN06451.1 - 0.0053 16.5 1.6 1.8 8.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 GAN06451.1 - 0.0054 16.0 0.0 0.69 9.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 GAN06451.1 - 0.0065 16.2 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 GAN06451.1 - 0.0095 16.1 0.0 6.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 GAN06451.1 - 0.022 14.5 0.0 8.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 GAN06451.1 - 0.044 13.7 1.9 4.1 7.3 0.0 3.7 4 0 0 4 4 3 0 NTPase T2SSE PF00437.20 GAN06451.1 - 0.061 12.4 0.0 2.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Hydin_ADK PF17213.3 GAN06451.1 - 0.079 13.2 1.6 80 3.4 0.0 4.0 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain IPT PF01745.16 GAN06451.1 - 0.12 11.8 0.1 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Fungal_trans PF04082.18 GAN06452.1 - 9.5e-32 110.1 0.2 2.2e-30 105.6 0.0 2.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN06452.1 - 4.6e-10 39.4 12.5 4.6e-10 39.4 12.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_PEP_C PF04513.12 GAN06453.1 - 0.02 14.9 12.8 0.11 12.5 5.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_BLRF2 PF05812.12 GAN06453.1 - 0.22 11.7 11.6 0.07 13.3 4.7 2.9 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DUF2018 PF09442.10 GAN06453.1 - 0.23 12.5 0.2 0.23 12.5 0.2 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF2018) DUF4407 PF14362.6 GAN06453.1 - 1.3 8.3 23.4 0.011 15.1 10.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2316 PF10078.9 GAN06453.1 - 5.2 7.4 10.7 1.9 8.7 0.2 3.6 3 2 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Methyltransf_31 PF13847.6 GAN06454.1 - 2.2e-12 47.0 0.0 2.7e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN06454.1 - 1.3e-07 32.2 0.0 2.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN06454.1 - 1.2e-06 29.0 0.0 2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN06454.1 - 0.0013 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAN06454.1 - 0.0017 19.1 0.1 0.0028 18.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN06454.1 - 0.0021 17.9 0.0 0.0024 17.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN06454.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family N2227 PF07942.12 GAN06454.1 - 0.017 14.3 0.0 2.7 7.1 0.1 2.2 1 1 1 2 2 2 0 N2227-like protein TehB PF03848.14 GAN06454.1 - 0.023 14.1 0.3 0.03 13.7 0.3 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 GAN06454.1 - 0.031 14.3 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAN06454.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Spermine_synth PF01564.17 GAN06454.1 - 0.098 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Spermine/spermidine synthase domain HA2 PF04408.23 GAN06455.1 - 3.8e-26 91.5 0.1 1.2e-25 89.8 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAN06455.1 - 4.8e-22 78.1 0.0 1e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAN06455.1 - 8.5e-13 48.6 0.0 2.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 GAN06455.1 - 3.2e-10 40.2 1.0 8.3e-10 38.9 1.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 GAN06455.1 - 2.7e-07 30.5 0.0 5.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAN06455.1 - 3.4e-05 23.6 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN06455.1 - 0.0001 22.6 0.0 0.00031 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAN06455.1 - 0.00033 19.8 0.1 0.00071 18.7 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 GAN06455.1 - 0.0056 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 GAN06455.1 - 0.0067 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Microtub_bd PF16796.5 GAN06455.1 - 0.01 15.8 0.2 0.55 10.2 0.1 2.6 3 0 0 3 3 3 1 Microtubule binding ABC_tran PF00005.27 GAN06455.1 - 0.016 15.7 0.3 1.1 9.7 0.1 3.3 2 1 1 3 3 3 0 ABC transporter Flavi_DEAD PF07652.14 GAN06455.1 - 0.031 14.2 0.2 0.084 12.9 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_7 PF12775.7 GAN06455.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 GAN06455.1 - 0.068 12.6 0.1 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 GAN06455.1 - 0.069 13.2 0.2 1.5 8.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAN06455.1 - 0.15 11.6 0.2 0.48 10.0 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain RRM_1 PF00076.22 GAN06456.1 - 4.7e-11 42.3 0.1 1e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN06456.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Sod_Cu PF00080.20 GAN06457.1 - 3.2e-49 166.7 4.9 3.8e-49 166.5 4.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 GAN06457.1 - 0.096 13.7 0.5 0.16 12.9 0.4 1.3 1 1 0 1 1 1 0 CHRD domain Epimerase PF01370.21 GAN06458.1 - 4.5e-09 36.1 0.2 2.9e-08 33.5 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAN06458.1 - 7.2e-09 35.8 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAN06458.1 - 1.9e-07 30.4 0.0 1.4e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAN06458.1 - 1.7e-06 27.8 0.0 4.8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 GAN06458.1 - 1.8e-05 24.1 0.1 0.016 14.4 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 GAN06458.1 - 0.033 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 GAN06458.1 - 0.036 14.3 0.0 0.15 12.3 0.0 1.8 1 1 1 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 GAN06458.1 - 0.15 12.3 0.1 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 GAN06459.1 - 3.3e-53 180.7 0.0 1.5e-38 132.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06459.1 - 2.2e-18 66.5 0.0 3.9e-18 65.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN06459.1 - 5.6e-08 32.4 0.0 1.5e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN06459.1 - 1.6e-05 24.3 0.1 2.5e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN06459.1 - 0.00021 21.3 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN06459.1 - 0.00049 19.2 0.1 0.014 14.3 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 GAN06459.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 GAN06459.1 - 0.073 11.8 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Y_phosphatase PF00102.27 GAN06460.1 - 9.1e-68 228.3 0.1 1.2e-67 227.9 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAN06460.1 - 1.2e-05 25.2 0.6 2.7e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GAN06460.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAN06460.1 - 0.00028 21.0 0.0 0.00073 19.7 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.14 GAN06460.1 - 0.0079 15.2 0.2 0.021 13.8 0.1 2.0 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain DUF5420 PF17457.2 GAN06460.1 - 0.01 15.7 0.9 0.16 11.9 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5420) Y_phosphatase2 PF03162.13 GAN06460.1 - 0.068 12.7 0.2 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF442 PF04273.13 GAN06460.1 - 0.17 12.0 0.1 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Mito_carr PF00153.27 GAN06461.1 - 5.2e-58 193.0 11.1 1.6e-23 82.4 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN06461.1 - 2e-05 23.9 4.6 0.007 15.6 4.6 3.0 1 1 0 1 1 1 1 Gammaproteobacterial serine protease SpoVAD PF07451.11 GAN06461.1 - 0.0098 14.6 1.1 0.015 14.1 1.1 1.4 1 1 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) RSN1_7TM PF02714.15 GAN06461.1 - 0.11 11.7 0.0 0.28 10.4 0.0 1.7 1 1 1 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Ribosomal_L30_N PF08079.12 GAN06462.1 - 2.2e-21 75.9 9.2 3.9e-21 75.1 9.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GAN06462.1 - 1.4e-17 63.3 1.3 1.4e-17 63.3 1.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e NinG PF05766.12 GAN06462.1 - 0.15 12.0 5.3 0.21 11.5 5.3 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Arf PF00025.21 GAN06463.1 - 3e-80 267.8 0.0 3.4e-80 267.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAN06463.1 - 3.1e-14 53.2 0.0 4.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAN06463.1 - 2.7e-13 49.8 1.0 2.3e-09 36.9 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAN06463.1 - 4.2e-13 49.1 0.0 5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAN06463.1 - 8.1e-13 48.3 0.0 9.2e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAN06463.1 - 2e-10 40.4 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN06463.1 - 5.1e-06 26.6 0.0 8.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAN06463.1 - 0.0051 16.1 0.3 0.016 14.5 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TPR_1 PF00515.28 GAN06464.1 - 5.5e-11 41.8 9.6 0.016 15.0 0.1 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06464.1 - 1e-10 42.0 6.6 3.8e-05 24.1 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN06464.1 - 1.5e-10 40.6 0.9 0.32 10.7 0.1 5.0 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.17 GAN06464.1 - 2.5e-10 39.7 21.3 0.029 14.5 0.2 9.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAN06464.1 - 9.2e-08 32.3 14.1 0.00017 21.8 1.8 5.1 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN06464.1 - 3.1e-07 30.6 14.2 0.069 14.0 0.2 7.2 6 2 2 8 8 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN06464.1 - 2.1e-06 27.5 19.2 1.1 9.7 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAN06464.1 - 2.5e-06 27.1 5.1 0.25 11.4 0.7 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN06464.1 - 2.8e-06 27.9 3.4 0.011 16.4 0.2 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAN06464.1 - 0.00013 22.0 7.1 0.012 15.8 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAN06464.1 - 0.00047 20.5 0.0 0.19 12.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN06464.1 - 0.0013 19.0 0.2 12 6.6 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAN06464.1 - 0.0049 17.2 0.6 10 6.5 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN06464.1 - 0.007 16.6 0.5 0.007 16.6 0.5 4.9 6 1 1 7 7 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GAN06464.1 - 0.011 15.2 0.1 0.011 15.2 0.1 4.0 4 1 0 4 4 4 0 MalT-like TPR region TPR_3 PF07720.12 GAN06464.1 - 0.076 13.0 0.3 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAN06464.1 - 0.11 12.4 10.7 0.16 11.9 0.4 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN06464.1 - 0.61 10.8 8.4 24 5.8 0.1 5.4 5 0 0 5 5 3 0 Tetratricopeptide repeat Vta1 PF04652.16 GAN06464.1 - 7.6 6.5 10.5 5.4 7.0 0.7 3.3 4 0 0 4 4 4 0 Vta1 like Myb_DNA-binding PF00249.31 GAN06465.1 - 1.4e-38 130.9 8.8 1.9e-13 50.4 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN06465.1 - 5.3e-30 103.5 3.3 5.6e-14 52.1 0.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAN06465.1 - 0.00017 21.9 4.6 0.12 12.8 0.0 4.0 3 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAN06465.1 - 0.00023 21.0 0.5 0.24 11.3 0.0 3.0 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 GAN06465.1 - 0.0047 17.0 0.0 5.3 7.1 0.0 3.3 1 1 2 3 3 3 2 SLIDE CNH PF00780.22 GAN06466.1 - 0.075 12.6 0.3 0.095 12.3 0.3 1.1 1 0 0 1 1 1 0 CNH domain Condensation PF00668.20 GAN06466.1 - 0.38 9.4 4.9 0.49 9.0 4.9 1.2 1 0 0 1 1 1 0 Condensation domain Ribosomal_L5e PF17144.4 GAN06467.1 - 9e-80 266.4 0.2 1.8e-79 265.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAN06467.1 - 2e-18 67.1 2.9 2e-18 67.1 2.9 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Lipin_mid PF16876.5 GAN06467.1 - 0.7 10.1 2.3 0.84 9.8 0.9 1.9 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain PhoD PF09423.10 GAN06468.1 - 3.1e-08 33.0 0.0 1.2e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase WD40 PF00400.32 GAN06469.1 - 2e-16 60.1 9.8 0.00086 20.1 0.0 8.5 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06469.1 - 4.1e-07 30.2 0.7 0.92 9.8 0.0 5.6 6 1 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PRCC PF10253.9 GAN06470.1 - 2.3e-20 74.3 19.1 9.2e-20 72.4 14.9 2.2 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting FHA PF00498.26 GAN06471.1 - 9.6e-15 54.7 0.1 1.8e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 GAN06471.1 - 1.6e-09 37.3 10.8 2.8e-09 36.6 10.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAN06471.1 - 4.2e-07 30.2 11.0 6.8e-07 29.5 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAN06471.1 - 0.0013 18.6 8.6 0.0027 17.6 8.6 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAN06471.1 - 0.0013 18.9 5.1 0.0028 17.9 5.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAN06471.1 - 0.0013 18.5 2.9 0.0027 17.5 2.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAN06471.1 - 0.0051 16.8 1.4 0.0092 16.0 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAN06471.1 - 0.018 14.9 11.4 0.034 14.0 11.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN06471.1 - 0.074 12.9 8.9 0.13 12.2 8.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN06471.1 - 0.091 12.7 10.9 0.16 11.8 10.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 GAN06471.1 - 0.64 10.0 6.2 1.1 9.2 6.2 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 GAN06471.1 - 1 9.0 5.7 1.8 8.2 5.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GAN06471.1 - 2.2 8.4 11.3 4.1 7.5 11.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Dicty_REP PF05086.12 GAN06471.1 - 5.4 4.9 5.9 11 3.9 5.9 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltr_RsmB-F PF01189.17 GAN06472.1 - 1.3e-38 132.7 0.0 1.9e-36 125.6 0.0 2.6 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAN06472.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase SWIRM PF04433.17 GAN06475.1 - 5.3e-29 100.4 0.1 1.5e-28 98.9 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAN06475.1 - 1.2e-23 82.9 6.2 1.2e-23 82.9 6.2 2.1 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GAN06475.1 - 8.3e-14 51.5 0.0 2.7e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN06475.1 - 2.9e-08 33.8 0.1 1.1e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 GAN06475.1 - 4.1e-06 26.5 4.9 8.7e-06 25.5 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SANT_DAMP1_like PF16282.5 GAN06475.1 - 0.0099 16.1 0.2 0.025 14.8 0.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Zn_ribbon_2 PF12674.7 GAN06475.1 - 0.018 15.7 0.4 0.058 14.1 0.4 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain Myb_DNA-bind_7 PF15963.5 GAN06475.1 - 0.054 13.4 0.0 0.054 13.4 0.0 2.9 3 0 0 3 3 3 0 Myb DNA-binding like Chordopox_RPO7 PF05864.12 GAN06475.1 - 0.23 11.8 0.8 0.52 10.6 0.8 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Sec16_C PF12931.7 GAN06476.1 - 1.7e-47 162.6 0.4 2.7e-47 161.9 0.4 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 DZR PF12773.7 GAN06476.1 - 0.2 11.7 2.1 0.4 10.7 2.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon bZIP_1 PF00170.21 GAN06477.1 - 2e-09 37.4 11.0 1.3e-08 34.8 11.0 2.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN06477.1 - 3.3e-07 30.3 10.2 1.5e-06 28.2 10.2 2.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAN06477.1 - 0.0061 17.1 9.3 0.0061 17.1 9.3 2.5 2 1 0 2 2 2 1 bZIP Maf transcription factor HALZ PF02183.18 GAN06477.1 - 0.059 13.6 3.3 8.6 6.7 2.2 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fib_alpha PF08702.10 GAN06477.1 - 0.25 11.6 8.7 1.7 8.8 7.1 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 GAN06477.1 - 0.92 10.0 8.5 0.058 13.8 1.5 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 GAN06477.1 - 1.2 9.7 15.8 0.15 12.5 8.5 3.2 3 1 0 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 GAN06477.1 - 1.2 9.5 5.5 0.88 9.9 2.9 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family CCDC-167 PF15188.6 GAN06477.1 - 4.1 7.8 8.1 8.6 6.8 6.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 GAN06477.1 - 7.8 7.2 12.2 2.2 8.9 4.7 3.6 3 1 0 3 3 3 0 SlyX FH2 PF02181.23 GAN06478.1 - 9.9e-81 271.7 1.8 9.9e-81 271.7 1.8 3.0 3 1 0 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.13 GAN06478.1 - 3.6e-45 153.8 0.3 3.6e-45 153.8 0.3 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAN06478.1 - 1.3e-37 129.3 0.3 1.3e-37 129.3 0.3 2.8 4 0 0 4 4 4 1 Diaphanous FH3 Domain Polysacc_deac_2 PF04748.13 GAN06478.1 - 0.0047 16.1 0.2 0.029 13.5 0.0 2.5 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase Drf_DAD PF06345.11 GAN06478.1 - 0.1 12.7 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 DRF Autoregulatory Domain Prefoldin PF02996.17 GAN06479.1 - 1.4e-16 60.5 4.5 5.6e-16 58.5 4.5 1.8 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 GAN06479.1 - 2.5e-05 24.3 0.6 3.8e-05 23.7 0.6 1.3 1 0 0 1 1 1 1 Prefoldin subunit FadA PF09403.10 GAN06479.1 - 0.0013 19.1 2.3 0.92 10.0 0.1 2.2 2 0 0 2 2 2 2 Adhesion protein FadA Scaffolding_pro PF11418.8 GAN06479.1 - 0.0014 19.2 0.3 0.0024 18.4 0.2 1.5 1 1 0 1 1 1 1 Phi29 scaffolding protein TMF_TATA_bd PF12325.8 GAN06479.1 - 0.0054 16.9 2.2 0.068 13.4 0.5 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding CEP63 PF17045.5 GAN06479.1 - 0.0098 15.8 1.6 0.02 14.8 1.6 1.7 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa TEX12 PF15219.6 GAN06479.1 - 0.04 14.2 0.5 0.081 13.3 0.5 1.7 1 1 0 1 1 1 0 Testis-expressed 12 Prefoldin_2 PF01920.20 GAN06479.1 - 0.079 12.9 6.8 0.62 10.0 0.5 2.3 1 1 0 2 2 2 0 Prefoldin subunit DUF5082 PF16888.5 GAN06479.1 - 0.13 12.6 6.7 0.96 9.7 6.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) UPF0449 PF15136.6 GAN06479.1 - 0.13 12.7 1.8 13 6.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Spc7 PF08317.11 GAN06479.1 - 0.14 11.1 4.2 0.51 9.2 4.2 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 GAN06479.1 - 0.15 12.1 5.8 1.7 8.7 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ApoO PF09769.9 GAN06479.1 - 0.28 11.1 1.4 15 5.5 0.1 2.2 1 1 1 2 2 2 0 Apolipoprotein O CC2-LZ PF16516.5 GAN06479.1 - 0.33 11.3 5.3 1.4 9.3 0.6 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator NPV_P10 PF05531.12 GAN06479.1 - 0.44 11.0 7.2 1.8e+02 2.6 7.2 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 GAN06479.1 - 0.77 9.7 10.8 1.2 9.0 4.5 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 GAN06479.1 - 1.2 9.3 6.3 0.98 9.6 0.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family COX4 PF02936.14 GAN06480.1 - 2.9e-41 140.7 0.1 3.3e-41 140.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV F-box-like PF12937.7 GAN06481.1 - 5.1e-11 42.3 0.2 0.00012 21.9 0.1 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 GAN06481.1 - 0.0013 18.6 0.2 0.44 10.5 0.1 2.8 2 0 0 2 2 2 2 F-box domain F-box_5 PF18511.1 GAN06481.1 - 0.047 13.3 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 F-box HAD PF12710.7 GAN06481.1 - 0.16 12.3 0.0 30 4.9 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Rubredoxin_2 PF18073.1 GAN06481.1 - 0.27 11.0 0.7 17 5.3 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain HSF_DNA-bind PF00447.17 GAN06482.1 - 1.4e-31 108.9 0.6 1.4e-31 108.9 0.6 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding EzrA PF06160.12 GAN06482.1 - 0.097 10.8 3.6 0.086 11.0 1.6 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 GAN06482.1 - 0.24 11.8 0.8 4.1 7.9 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RskA PF10099.9 GAN06482.1 - 3 8.1 15.0 2.7 8.3 2.4 3.5 4 0 0 4 4 4 0 Anti-sigma-K factor rskA GATase_2 PF00310.21 GAN06483.1 - 3.2e-178 592.7 0.0 4.4e-178 592.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GAN06483.1 - 7.6e-155 515.6 1.0 1e-153 511.8 0.1 2.4 3 0 0 3 3 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GAN06483.1 - 3.9e-117 390.7 0.0 3.9e-116 387.4 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAN06483.1 - 5.7e-83 277.2 3.7 9.4e-83 276.5 3.7 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GAN06483.1 - 1.5e-26 93.3 0.1 7.5e-26 91.0 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GAN06483.1 - 2.3e-23 82.1 0.1 4.8e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 GAN06483.1 - 6.9e-09 35.8 0.0 2.7e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAN06483.1 - 6.2e-08 33.1 0.1 7.1e-05 23.3 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN06483.1 - 1.2e-06 28.1 0.8 0.15 11.3 0.1 4.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN06483.1 - 3.5e-06 26.8 0.4 0.019 14.5 0.1 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAN06483.1 - 8.8e-06 25.3 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAN06483.1 - 6.8e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAN06483.1 - 7.1e-05 21.7 0.1 7.1e-05 21.7 0.1 2.2 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 GAN06483.1 - 0.00052 20.4 0.0 1.1 9.8 0.1 3.1 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 GAN06483.1 - 0.00063 18.9 0.3 0.0035 16.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAN06483.1 - 0.0059 15.9 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAN06483.1 - 0.009 15.1 0.6 0.052 12.6 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 GAN06483.1 - 0.0099 15.9 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 GAN06483.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GAN06483.1 - 0.017 14.4 0.2 0.23 10.7 0.1 2.4 2 0 0 2 2 2 0 Thi4 family FMN_dh PF01070.18 GAN06483.1 - 0.057 12.4 0.5 0.19 10.7 0.5 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_2 PF03446.15 GAN06483.1 - 0.06 13.5 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAN06483.1 - 0.062 12.9 0.2 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Prot_ATP_ID_OB PF16450.5 GAN06483.1 - 0.075 13.0 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Shikimate_DH PF01488.20 GAN06483.1 - 0.095 12.8 0.0 45 4.1 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GATase_6 PF13522.6 GAN06483.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain LSM14 PF12701.7 GAN06484.1 - 5.1e-31 106.6 0.1 1.3e-30 105.3 0.1 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GAN06484.1 - 3.2e-07 31.2 7.4 3.2e-07 31.2 7.4 4.5 3 2 0 3 3 3 1 FDF domain SM-ATX PF14438.6 GAN06484.1 - 1.3e-06 28.5 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain COQ7 PF03232.13 GAN06486.1 - 8.8e-78 260.0 0.2 1.1e-77 259.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 SCP2 PF02036.17 GAN06487.1 - 1e-23 83.7 2.0 1.3e-23 83.4 2.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAN06487.1 - 0.0024 18.1 0.3 0.0034 17.6 0.3 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 GAN06487.1 - 0.12 12.8 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Ribo_biogen_C PF04034.13 GAN06488.1 - 9.1e-51 170.9 0.0 1.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 GAN06488.1 - 1.8e-11 43.6 1.4 3e-11 43.0 1.4 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI TFIIA PF03153.13 GAN06488.1 - 1.4 8.8 13.0 2.3 8.1 13.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCV_T PF01571.21 GAN06489.1 - 1.5e-10 40.9 0.0 2.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Ribosomal_L17 PF01196.19 GAN06490.1 - 6e-37 126.4 0.3 1.2e-36 125.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 Melibiase_2_C PF17450.2 GAN06490.1 - 0.12 12.6 0.0 6.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain Arrestin_N PF00339.29 GAN06491.1 - 1.3e-13 51.3 0.7 4.3e-07 30.1 0.0 3.8 2 2 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN06491.1 - 1.9e-12 47.8 2.1 1.2e-08 35.5 1.9 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain PIF1 PF05970.14 GAN06492.1 - 0.028 13.6 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF2532 PF10811.8 GAN06493.1 - 0.06 13.4 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) MMS22L_N PF14910.6 GAN06494.1 - 0.04 12.4 0.0 0.048 12.1 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal HAD_SAK_2 PF18143.1 GAN06494.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 1 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins KilA-N PF04383.13 GAN06495.1 - 0.00075 19.3 0.2 0.0024 17.7 0.0 2.0 2 0 0 2 2 2 1 KilA-N domain ESSS PF10183.9 GAN06495.1 - 2.7 8.2 4.8 1.1 9.6 0.0 2.8 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PEPCK_ATP PF01293.20 GAN06496.1 - 1.3e-219 729.6 0.0 1.5e-219 729.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 GAN06496.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain EF-hand_1 PF00036.32 GAN06497.1 - 2e-20 70.7 3.4 1e-07 31.0 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GAN06497.1 - 4.1e-19 68.8 0.5 1.2e-13 51.3 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAN06497.1 - 2.8e-18 65.5 6.4 1.7e-08 34.2 0.0 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAN06497.1 - 3.3e-14 51.5 1.4 7.2e-05 22.4 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 GAN06497.1 - 8.3e-12 44.0 3.5 0.00084 18.7 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 GAN06497.1 - 1.3e-08 35.0 0.1 0.0026 18.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAN06497.1 - 2.4e-08 33.9 1.6 0.011 15.6 0.3 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 GAN06497.1 - 0.00041 20.5 4.3 0.3 11.3 1.6 3.1 1 1 2 3 3 3 2 Dockerin type I domain SurA_N_3 PF13624.6 GAN06497.1 - 0.0032 17.3 0.1 0.007 16.2 0.0 1.6 2 0 0 2 2 2 1 SurA N-terminal domain p25-alpha PF05517.12 GAN06497.1 - 0.0074 16.5 0.4 0.17 12.0 0.5 2.0 1 1 1 2 2 2 1 p25-alpha SPARC_Ca_bdg PF10591.9 GAN06497.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_60s PF00428.19 GAN06497.1 - 0.041 14.5 0.2 0.5 11.0 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein SurA_N_2 PF13623.6 GAN06497.1 - 0.058 13.3 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 SurA N-terminal domain GrpE PF01025.19 GAN06497.1 - 0.069 12.8 0.6 0.36 10.5 0.6 2.0 1 1 0 1 1 1 0 GrpE DUF1456 PF07308.13 GAN06497.1 - 0.14 12.6 0.5 2.2 8.7 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1456) E1_dh PF00676.20 GAN06498.1 - 3.3e-64 216.7 0.0 4.4e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 GAN06498.1 - 2.2e-61 206.6 0.0 3.3e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GAN06498.1 - 1e-55 187.6 0.2 1.8e-55 186.8 0.2 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GAN06498.1 - 5.4e-19 67.5 0.5 5.4e-19 67.5 0.5 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Peptidase_S10 PF00450.22 GAN06499.1 - 1.6e-107 360.5 3.9 2e-107 360.2 3.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DNase-RNase PF02577.14 GAN06500.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease DUF3492 PF11997.8 GAN06500.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) TRAPP PF04051.16 GAN06501.1 - 5.7e-39 133.1 0.0 7.2e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.10 GAN06501.1 - 0.11 12.7 0.0 18 5.7 0.0 2.2 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Pet191_N PF10203.9 GAN06502.1 - 2.5e-25 88.6 7.2 2.7e-25 88.4 7.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GAN06502.1 - 0.41 10.7 9.2 9.6 6.3 4.1 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Dickkopf_N PF04706.12 GAN06502.1 - 0.57 10.7 5.8 10 6.7 4.4 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Carboxyl_trans PF01039.22 GAN06503.1 - 3.3e-148 494.4 0.0 4.2e-148 494.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 GAN06503.1 - 0.034 13.6 0.0 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 GAN06503.1 - 0.26 10.5 0.1 0.26 10.5 0.1 1.7 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN06504.1 - 5.8e-67 226.6 0.0 7.2e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAN06504.1 - 2.1e-19 69.8 0.0 4.7e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Val_tRNA-synt_C PF10458.9 GAN06504.1 - 0.16 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm ECH_2 PF16113.5 GAN06505.1 - 2.8e-84 283.5 0.0 3.4e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAN06505.1 - 6.2e-33 114.1 0.0 2.1e-26 92.7 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 GAN06507.1 - 1.1e-72 244.9 0.0 1.7e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN06507.1 - 2.2e-16 60.6 0.1 4.1e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 GAN06507.1 - 0.0039 17.5 0.1 0.19 12.0 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Beach PF02138.18 GAN06509.1 - 1.6e-123 411.5 0.0 4.2e-123 410.1 0.0 1.8 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 GAN06509.1 - 9.3e-12 44.9 3.4 2e-11 43.8 3.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 GAN06509.1 - 2.2e-09 37.3 0.0 2.2e-09 37.3 0.0 2.9 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH WD40 PF00400.32 GAN06509.1 - 2.8e-08 34.3 9.7 0.0007 20.4 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4704 PF15787.5 GAN06509.1 - 1.3e-07 31.1 0.0 1.3e-07 31.1 0.0 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 GAN06509.1 - 9.7e-07 29.1 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily zf-CRD PF17979.1 GAN06509.1 - 0.0015 18.7 7.4 0.038 14.1 0.9 3.3 2 0 0 2 2 2 2 Cysteine rich domain with multizinc binding regions DUF4800 PF16057.5 GAN06509.1 - 0.0082 15.4 11.1 0.0032 16.8 7.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) IBR PF01485.21 GAN06509.1 - 0.03 14.5 7.5 0.071 13.3 7.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 GAN06509.1 - 4.8 7.4 7.5 12 6.2 7.5 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger RNA_pol_3_Rpc31 PF11705.8 GAN06510.1 - 3.9e-34 118.9 9.4 3.9e-34 118.9 9.4 1.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 GAN06510.1 - 0.051 12.9 13.4 0.053 12.9 13.4 1.0 1 0 0 1 1 1 0 BUD22 FGF-BP1 PF06473.12 GAN06510.1 - 0.39 10.5 2.8 0.52 10.1 2.8 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Pyr_redox_2 PF07992.14 GAN06511.1 - 1.1e-46 159.5 0.0 1.5e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN06511.1 - 4e-07 30.5 0.4 0.0017 18.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN06511.1 - 0.028 13.7 0.8 16 4.6 0.0 3.4 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF5321 PF17254.2 GAN06512.1 - 3.7e-11 42.7 1.3 1.1e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5321) Band_3_cyto PF07565.13 GAN06512.1 - 0.043 13.6 3.5 0.061 13.1 3.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SpoIIID PF12116.8 GAN06512.1 - 0.096 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D RNase_HII PF01351.18 GAN06513.1 - 3.1e-59 200.1 0.0 6.2e-59 199.2 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease HII FA_hydroxylase PF04116.13 GAN06514.1 - 6.6e-26 91.2 21.7 1e-25 90.6 21.7 1.3 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily Pkinase PF00069.25 GAN06516.1 - 3.8e-70 236.3 0.0 6.4e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06516.1 - 1.8e-49 168.4 0.0 3.6e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 GAN06516.1 - 4.2e-08 33.4 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 GAN06516.1 - 1.1e-06 28.3 1.3 0.00043 19.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like SAM_2 PF07647.17 GAN06516.1 - 2.6e-06 27.4 0.5 5.3e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 GAN06516.1 - 3.4e-05 22.8 0.1 3.4e-05 22.8 0.1 2.3 3 0 0 3 3 3 1 Fungal protein kinase SAM_1 PF00536.30 GAN06516.1 - 0.00025 21.4 0.3 0.00045 20.6 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HNF-1_N PF04814.13 GAN06516.1 - 0.0032 18.1 3.3 0.0032 18.1 3.3 2.8 3 0 0 3 3 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus APH PF01636.23 GAN06516.1 - 0.025 14.5 0.1 0.35 10.7 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RA PF00788.23 GAN06516.1 - 0.037 14.7 0.1 0.037 14.7 0.1 2.3 3 0 0 3 3 2 0 Ras association (RalGDS/AF-6) domain DUF5401 PF17380.2 GAN06516.1 - 0.039 12.0 3.5 0.09 10.8 3.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Haspin_kinase PF12330.8 GAN06516.1 - 0.08 11.9 0.1 0.08 11.9 0.1 2.4 2 0 0 2 2 2 0 Haspin like kinase domain PRCC PF10253.9 GAN06516.1 - 8.7 7.1 16.6 0.82 10.4 7.8 2.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting TF_Zn_Ribbon PF08271.12 GAN06517.1 - 1e-05 24.9 4.6 2e-05 24.0 4.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RPA_interact_C PF14768.6 GAN06517.1 - 0.0033 17.9 2.6 0.0034 17.9 0.3 2.3 2 0 0 2 2 2 1 Replication protein A interacting C-terminal Prok-RING_1 PF14446.6 GAN06517.1 - 0.0056 16.6 2.8 0.013 15.4 2.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.6 GAN06517.1 - 0.015 14.7 3.1 0.032 13.6 3.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 GAN06517.1 - 0.04 13.9 4.2 0.09 12.8 4.2 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.10 GAN06517.1 - 0.08 12.7 2.3 0.19 11.5 2.3 1.7 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-RRN7 PF11781.8 GAN06517.1 - 0.083 12.6 3.4 0.23 11.2 3.4 1.8 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TackOD1 PF18551.1 GAN06517.1 - 0.09 12.4 1.4 0.13 11.9 0.4 1.8 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DUF2318 PF10080.9 GAN06517.1 - 0.09 12.9 1.5 0.19 11.9 1.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DZR PF12773.7 GAN06517.1 - 0.15 12.1 0.9 0.31 11.1 0.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon PHD PF00628.29 GAN06517.1 - 5.3 7.0 5.6 0.81 9.6 1.5 1.8 2 0 0 2 2 2 0 PHD-finger Kin17_mid PF10357.9 GAN06518.1 - 7.8e-48 161.6 0.2 7.8e-48 161.6 0.2 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein Cdc6_C PF09079.11 GAN06518.1 - 0.0031 17.5 0.1 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain zf-met PF12874.7 GAN06518.1 - 0.018 15.4 5.3 0.038 14.4 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN06518.1 - 0.028 14.7 5.8 0.028 14.7 5.8 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PBP3 PF18056.1 GAN06518.1 - 0.05 13.7 1.6 0.11 12.6 1.2 1.8 2 0 0 2 2 2 0 Penicillin Binding Protein 3 Domain OB_NTP_bind PF07717.16 GAN06519.1 - 7.2e-22 77.6 0.1 3.1e-21 75.5 0.1 2.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAN06519.1 - 2.7e-18 66.2 0.1 2.7e-18 66.2 0.1 4.5 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAN06519.1 - 1.2e-15 57.8 0.0 3.7e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN06519.1 - 2e-06 27.7 0.0 4.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAN06519.1 - 0.00014 22.1 0.7 0.0036 17.6 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAN06519.1 - 0.00055 19.7 0.4 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain PWI PF01480.17 GAN06519.1 - 0.0017 18.6 0.3 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 PWI domain T2SSE PF00437.20 GAN06519.1 - 0.0044 16.1 0.0 0.014 14.4 0.0 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 GAN06519.1 - 0.0082 16.5 0.5 0.039 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 GAN06519.1 - 0.016 14.9 0.1 0.15 11.6 0.1 2.6 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 GAN06519.1 - 0.13 11.8 0.2 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Mito_carr PF00153.27 GAN06520.1 - 8.4e-73 240.4 1.8 6.5e-26 90.1 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAN06520.1 - 8.3e-17 61.4 8.4 0.00053 20.4 0.2 5.1 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.6 GAN06520.1 - 7.5e-16 56.6 6.9 4.5e-05 23.1 0.0 6.3 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 GAN06520.1 - 2.4e-15 54.9 10.7 6.5e-06 25.3 0.0 5.7 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 GAN06520.1 - 2.1e-10 40.3 5.0 0.06 13.2 0.3 4.7 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAN06520.1 - 0.002 17.6 5.2 1.6 8.4 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 GAN06520.1 - 0.045 14.1 0.3 3.5 8.0 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain Serine_protease PF18405.1 GAN06520.1 - 0.2 10.8 1.3 4.6 6.3 0.1 3.2 2 1 1 3 3 3 0 Gammaproteobacterial serine protease EF-hand_4 PF12763.7 GAN06520.1 - 2.2 8.3 5.1 2.4 8.1 0.2 3.0 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand PIG-S PF10510.9 GAN06521.1 - 2.2e-120 402.9 7.1 3.1e-120 402.4 7.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein HhH-GPD PF00730.25 GAN06521.1 - 1.7e-23 83.1 0.0 5e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 GAN06521.1 - 5.7e-17 61.7 0.0 1.3e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 GAN06521.1 - 8.7e-06 25.4 0.0 2.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 GAN06521.1 - 0.0039 17.5 7.2 0.0073 16.6 7.2 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III MnmE_helical PF12631.7 GAN06521.1 - 0.02 15.1 0.0 0.061 13.5 0.0 2.0 1 1 0 1 1 1 0 MnmE helical domain EPO_TPO PF00758.18 GAN06521.1 - 0.079 13.0 1.6 5 7.1 0.1 3.2 3 1 1 4 4 4 0 Erythropoietin/thrombopoietin Adap_comp_sub PF00928.21 GAN06522.1 - 4.3e-85 285.3 0.1 5.6e-85 284.9 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ribosomal_L14 PF00238.19 GAN06522.1 - 1.4e-45 154.3 1.2 3.5e-45 153.0 1.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Clat_adaptor_s PF01217.20 GAN06522.1 - 0.0049 16.8 0.2 0.0096 15.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DnaJ-X PF14308.6 GAN06523.1 - 2.5e-55 187.2 0.4 2.5e-55 187.2 0.4 3.7 4 0 0 4 4 4 1 X-domain of DnaJ-containing RRP7 PF12923.7 GAN06523.1 - 1.6e-34 118.5 16.1 1.6e-34 118.5 16.1 3.8 4 0 0 4 4 4 2 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DnaJ PF00226.31 GAN06523.1 - 1.3e-28 98.8 1.9 3.4e-27 94.4 2.7 2.8 2 0 0 2 2 2 1 DnaJ domain RRM_Rrp7 PF17799.1 GAN06523.1 - 2.3e-14 53.5 1.3 2.3e-14 53.5 1.3 2.6 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain zinc_ribbon_12 PF11331.8 GAN06523.1 - 0.077 12.8 0.4 0.22 11.4 0.4 1.8 1 0 0 1 1 1 0 Probable zinc-ribbon domain DDE_3 PF13358.6 GAN06524.1 - 4.7e-22 78.3 0.0 8.2e-20 71.0 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease EphA2_TM PF14575.6 GAN06524.1 - 0.027 15.4 0.5 0.027 15.4 0.5 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ACR_tran PF00873.19 GAN06524.1 - 0.051 11.2 0.1 0.063 10.9 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family STE3 PF02076.15 GAN06524.1 - 0.077 12.2 0.8 0.12 11.6 0.8 1.2 1 0 0 1 1 1 0 Pheromone A receptor Neur_chan_memb PF02932.16 GAN06524.1 - 0.15 12.1 1.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region HemY_N PF07219.13 GAN06524.1 - 0.24 11.6 2.7 0.46 10.7 2.7 1.4 1 0 0 1 1 1 0 HemY protein N-terminus SKG6 PF08693.10 GAN06524.1 - 8.6 5.9 17.8 20 4.7 17.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_transf_24 PF18404.1 GAN06527.1 - 3e-153 508.9 2.4 5.7e-153 507.9 2.4 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GAN06527.1 - 4.2e-55 187.5 0.4 1.7e-54 185.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 GAN06527.1 - 3e-39 134.0 0.2 8.9e-39 132.5 0.2 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GAN06527.1 - 4.9e-37 126.4 0.0 1.2e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 GAN06527.1 - 6.8e-35 120.7 2.5 1.4e-34 119.6 2.5 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 GAN06527.1 - 1.1e-33 117.0 0.7 7.7e-30 104.4 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain MFS_1 PF07690.16 GAN06527.1 - 6.7e-22 77.9 53.3 8.6e-20 70.9 28.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_8 PF01501.20 GAN06527.1 - 4.7e-06 26.3 0.4 1.6e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 MFS_1_like PF12832.7 GAN06527.1 - 8.1e-05 21.6 7.6 8.1e-05 21.6 7.6 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF3784 PF12650.7 GAN06527.1 - 0.0075 16.4 0.6 0.0075 16.4 0.6 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3784) DUF2830 PF11125.8 GAN06527.1 - 1.3 9.1 4.0 0.86 9.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) Androgen_recep PF02166.16 GAN06527.1 - 8.6 5.1 5.9 0.68 8.7 1.1 1.5 2 0 0 2 2 2 0 Androgen receptor COG2 PF06148.11 GAN06528.1 - 2.2e-31 108.7 3.5 2.2e-31 108.7 3.5 3.2 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 GAN06528.1 - 8e-27 94.1 0.2 4.2e-26 91.8 0.2 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 GAN06528.1 - 8.3e-07 29.0 0.1 4.9e-06 26.5 0.1 2.5 1 0 0 1 1 1 1 Vps51/Vps67 Spc7 PF08317.11 GAN06528.1 - 0.0069 15.3 2.3 0.0069 15.3 2.3 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF5446 PF17522.2 GAN06528.1 - 0.0083 16.3 6.5 0.1 12.8 0.3 5.1 5 0 0 5 5 5 1 Family of unknown function (DUF5446) DUF3829 PF12889.7 GAN06528.1 - 0.26 10.7 3.2 2.7 7.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) COG5 PF10392.9 GAN06528.1 - 0.6 10.3 6.3 0.97 9.6 2.9 2.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Tup_N PF08581.10 GAN06528.1 - 1.6 9.1 5.9 2.8 8.3 1.0 3.3 2 1 0 2 2 2 0 Tup N-terminal Syntaxin_2 PF14523.6 GAN06528.1 - 6.2 7.3 13.5 1.7 9.0 1.2 4.2 3 1 1 4 4 4 0 Syntaxin-like protein MT-A70 PF05063.14 GAN06529.1 - 8.4e-13 48.6 0.4 1.9e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 MT-A70 Methyltransf_21 PF05050.12 GAN06529.1 - 8.1e-06 26.0 0.0 4.8e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase FkbM domain PilJ PF13675.6 GAN06529.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CAP_N PF01213.19 GAN06529.1 - 1.1 8.6 8.2 3 7.2 7.1 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GDE_N PF12439.8 GAN06530.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 1 0 1 1 1 0 Glycogen debranching enzyme N terminal DUF3455 PF11937.8 GAN06531.1 - 7.3e-07 29.7 0.2 1.8e-06 28.4 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2486 PF10667.9 GAN06531.1 - 3 8.0 18.7 1.3 9.2 16.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) DNA_pol_B_thumb PF14791.6 GAN06532.1 - 3.5e-17 62.3 0.0 7.4e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 GAN06532.1 - 2.5e-13 50.2 0.0 5.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 GAN06532.1 - 8.4e-13 47.9 0.1 1.1e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 GAN06532.1 - 1.3e-12 47.9 0.2 3.3e-12 46.6 0.2 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH_8 PF14716.6 GAN06532.1 - 2e-12 47.3 0.1 1.9e-11 44.2 0.7 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 GAN06532.1 - 0.0011 19.2 0.0 0.0051 17.1 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain BRCT PF00533.26 GAN06532.1 - 0.0028 18.0 1.1 0.016 15.6 0.2 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain zf-HC5HC2H PF13771.6 GAN06533.1 - 1.8e-10 40.9 2.8 1.8e-10 40.9 2.8 3.8 2 1 1 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAN06533.1 - 5.4e-10 39.4 3.0 5.4e-10 39.4 3.0 4.0 3 1 0 4 4 4 1 PHD-zinc-finger like domain N6_N4_Mtase PF01555.18 GAN06533.1 - 2.2e-08 34.1 0.5 0.0056 16.4 0.0 2.8 3 0 0 3 3 3 2 DNA methylase MBT PF02820.18 GAN06533.1 - 3.1e-05 24.2 0.5 0.15 12.4 0.0 3.3 3 0 0 3 3 3 2 mbt repeat CRAL_TRIO PF00650.20 GAN06534.1 - 9.5e-32 109.9 0.3 4.3e-26 91.5 0.3 2.5 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN06534.1 - 0.0069 16.5 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAN06534.1 - 0.074 13.2 1.3 0.4 10.8 1.3 2.1 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain Glycos_transf_2 PF00535.26 GAN06535.1 - 0.0039 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 PMP22_Claudin PF00822.20 GAN06535.1 - 0.044 13.6 0.4 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Pik1 PF11522.8 GAN06535.1 - 0.067 13.2 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 SMC_N PF02463.19 GAN06536.1 - 8.6e-25 87.5 20.5 1.2e-14 54.3 1.6 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAN06536.1 - 2.1e-13 51.3 26.6 2.1e-13 51.3 26.6 6.3 1 1 1 3 3 3 1 AAA domain AAA_15 PF13175.6 GAN06536.1 - 9.7e-10 38.7 16.1 9.7e-10 38.7 16.1 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 GAN06536.1 - 5e-07 29.8 8.7 0.0036 17.1 3.6 3.5 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAN06536.1 - 2.3e-05 24.0 0.0 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAN06536.1 - 0.012 15.8 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_hinge PF06470.13 GAN06536.1 - 0.063 13.6 0.1 0.32 11.3 0.0 2.3 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain AAA_16 PF13191.6 GAN06536.1 - 0.11 12.9 4.6 0.35 11.3 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain DUF1843 PF08898.10 GAN06536.1 - 2.2 8.8 5.1 4.6 7.8 2.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) GPI-anchored PF10342.9 GAN06537.1 - 3.2e-11 43.9 0.1 6.2e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family C2 PF00168.30 GAN06538.1 - 9.3e-15 54.8 0.0 4e-14 52.8 0.0 2.0 1 1 1 2 2 2 1 C2 domain Glycos_transf_1 PF00534.20 GAN06539.1 - 4e-30 104.6 0.0 7e-29 100.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN06539.1 - 8.3e-15 55.2 0.0 1.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAN06539.1 - 1.4e-12 48.2 0.0 4.3e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAN06539.1 - 1e-07 32.5 0.0 1.7e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAN06539.1 - 0.0014 19.0 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 GAN06539.1 - 0.43 10.6 1.8 23 4.9 0.3 3.3 2 1 1 3 3 3 0 ALG11 mannosyltransferase N-terminus LSM PF01423.22 GAN06540.1 - 8.4e-16 57.4 0.2 1e-15 57.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain DNA_pol_B PF00136.21 GAN06541.1 - 8.2e-125 417.1 0.1 8.2e-125 417.1 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 GAN06541.1 - 1.3e-53 181.6 6.9 2.3e-53 180.7 6.9 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 GAN06541.1 - 2.3e-42 145.4 0.0 4.5e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 GAN06541.1 - 5.4e-07 29.6 10.2 2.3e-06 27.6 10.2 2.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 GAN06541.1 - 6.3e-05 22.0 0.1 0.00027 19.9 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 GAN06541.1 - 0.0035 16.0 0.5 0.0065 15.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) YL1 PF05764.13 GAN06541.1 - 0.004 17.3 12.1 0.0077 16.4 12.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein DNA_pol_B_exo2 PF10108.9 GAN06541.1 - 0.0053 16.5 0.1 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Usp PF00582.26 GAN06542.1 - 3.7e-18 66.4 0.0 6e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family DUF4729 PF15866.5 GAN06542.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) OHCU_decarbox PF09349.10 GAN06544.1 - 0.11 13.0 0.5 0.18 12.3 0.0 1.6 2 0 0 2 2 2 0 OHCU decarboxylase PH PF00169.29 GAN06545.1 - 8.9e-42 141.9 8.8 6.9e-22 77.9 0.0 2.9 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 GAN06545.1 - 4.6e-14 52.7 12.0 1.3e-06 28.8 5.8 4.0 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 GAN06545.1 - 7e-11 42.2 7.7 3.5e-05 23.8 3.8 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 GAN06545.1 - 9.2e-11 41.9 6.0 0.00025 21.3 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain Peptidase_S9 PF00326.21 GAN06545.1 - 2.5e-08 33.6 0.1 5.7e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PH_9 PF15410.6 GAN06545.1 - 2.1e-05 24.8 7.6 0.045 14.1 5.7 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain Abhydrolase_1 PF00561.20 GAN06545.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN06545.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PH_13 PF16652.5 GAN06545.1 - 0.039 13.8 2.9 2.7 7.8 1.3 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain BCL_N PF04714.13 GAN06545.1 - 1.9 8.6 4.7 3.7 7.7 1.6 2.5 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Glyco_hydro_38N PF01074.22 GAN06546.1 - 1.4e-83 280.7 0.1 2.2e-83 280.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAN06546.1 - 1.2e-54 185.6 0.0 2.1e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAN06546.1 - 3.7e-22 78.3 0.0 5.4e-21 74.6 0.0 2.6 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 GAN06546.1 - 1.9e-09 37.2 0.0 3.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro38C2 PF17677.1 GAN06546.1 - 2e-07 31.0 0.0 8.5e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF3603 PF12227.8 GAN06546.1 - 0.029 13.7 0.2 0.061 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) cNMP_binding PF00027.29 GAN06548.1 - 8.1e-30 102.7 2.2 1.5e-17 63.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 GAN06548.1 - 3.5e-10 39.4 1.8 7e-10 38.4 1.8 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Peptidase_S10 PF00450.22 GAN06549.1 - 1.8e-99 334.0 2.3 2.2e-99 333.7 2.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Adaptin_N PF01602.20 GAN06550.1 - 8.4e-147 489.9 8.4 1e-146 489.6 8.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 GAN06550.1 - 5.5e-23 81.4 1.5 1.3e-22 80.2 1.5 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 GAN06550.1 - 6.2e-09 36.1 0.4 6.2e-09 36.1 0.4 3.6 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAN06550.1 - 0.0041 17.5 1.9 0.91 10.0 0.1 4.4 5 0 0 5 5 5 1 HEAT repeats RIX1 PF08167.12 GAN06550.1 - 0.011 15.5 0.0 0.065 13.0 0.0 2.4 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis HEAT PF02985.22 GAN06550.1 - 0.11 12.8 0.2 1.4e+02 3.1 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat PDEase_I PF00233.19 GAN06551.1 - 7.8e-79 264.7 0.4 1.8e-78 263.6 0.4 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 GAN06551.1 - 0.0015 18.7 0.0 0.011 15.8 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain LAG1-DNAbind PF09271.11 GAN06552.1 - 4.1e-44 150.9 19.5 1.1e-23 84.5 0.1 3.9 2 1 1 3 3 3 2 LAG1, DNA binding BTD PF09270.10 GAN06552.1 - 2.5e-22 79.8 0.0 2.8e-18 66.6 0.0 3.5 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain Dicty_REP PF05086.12 GAN06552.1 - 1 7.3 4.0 1.8 6.4 4.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CPSF100_C PF13299.6 GAN06552.1 - 1.8 8.7 9.5 0.38 10.9 4.7 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol PF00940.19 GAN06553.1 - 3.5e-182 605.9 0.0 4.6e-182 605.5 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GAN06553.1 - 1e-101 340.7 0.0 1e-101 340.7 0.0 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 GAN06553.1 - 1.1e-06 28.7 0.0 3.5e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 PPR repeat family PPR_1 PF12854.7 GAN06553.1 - 0.0053 16.4 0.8 1.7 8.4 0.0 2.7 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 GAN06553.1 - 0.045 13.8 0.1 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Zds_C PF08632.10 GAN06554.1 - 2.4e-12 46.4 0.7 2e-11 43.5 0.3 2.2 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term VARLMGL PF14383.6 GAN06554.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 DUF761-associated sequence motif Pneumo_att_G PF05539.11 GAN06554.1 - 0.98 8.9 7.7 1.4 8.5 7.7 1.4 1 1 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Metallophos PF00149.28 GAN06555.1 - 4.6e-38 131.8 0.2 6.6e-38 131.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN06555.1 - 6.8e-16 58.4 0.0 1.5e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain CAF-1_p60_C PF15512.6 GAN06555.1 - 0.64 10.5 13.4 1 9.8 13.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal zf-H2C2_2 PF13465.6 GAN06556.1 - 3.7e-11 42.9 10.8 2.4e-08 34.0 1.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAN06556.1 - 3.7e-10 39.7 10.6 2.5e-06 27.6 1.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN06556.1 - 2.9e-09 37.0 8.4 0.00026 21.6 1.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN06556.1 - 7.5e-05 22.9 0.1 0.48 10.8 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 GAN06556.1 - 8.1e-05 22.8 3.6 0.00016 21.9 3.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 GAN06556.1 - 0.00099 18.8 2.5 0.033 14.0 0.2 3.0 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 GAN06556.1 - 0.0016 18.8 1.3 0.051 14.0 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 GAN06556.1 - 0.0084 16.5 2.0 3.9 8.0 0.8 2.5 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 GAN06556.1 - 0.011 16.0 4.8 0.31 11.4 2.6 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 GAN06556.1 - 0.013 15.3 2.0 0.91 9.4 0.4 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 GAN06556.1 - 0.017 14.9 4.3 0.71 9.7 0.5 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 GAN06556.1 - 0.038 13.9 3.3 0.038 13.9 3.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 GAN06556.1 - 0.059 13.2 4.5 1.9 8.3 0.5 2.5 1 1 1 2 2 2 0 GAGA factor Zn_ribbon_SprT PF17283.2 GAN06556.1 - 0.18 11.7 4.1 0.61 10.0 4.1 1.9 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 GAN06556.1 - 0.22 11.6 3.7 0.31 11.1 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.9 GAN06556.1 - 0.88 9.3 6.0 1.7 8.3 2.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) FlxA PF14282.6 GAN06556.1 - 3.9 7.5 8.1 9 6.3 8.1 1.5 1 0 0 1 1 1 0 FlxA-like protein ABC_tran PF00005.27 GAN06557.1 - 1.3e-24 87.2 0.0 2e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAN06557.1 - 1.1e-07 32.0 0.1 0.0037 17.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAN06557.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 GAN06557.1 - 0.0012 19.2 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 GAN06557.1 - 0.0016 18.4 0.4 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 GAN06557.1 - 0.0018 17.8 0.0 0.0079 15.7 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAN06557.1 - 0.0023 17.7 0.1 0.007 16.1 0.0 1.9 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GAN06557.1 - 0.0028 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAN06557.1 - 0.0032 18.0 0.0 0.0057 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAN06557.1 - 0.004 16.6 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 GAN06557.1 - 0.0041 17.1 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 GAN06557.1 - 0.0042 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN06557.1 - 0.0073 16.6 0.1 0.013 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN06557.1 - 0.016 15.3 0.1 0.033 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAN06557.1 - 0.019 15.5 0.0 0.034 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAN06557.1 - 0.027 14.5 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 GAN06557.1 - 0.031 14.2 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain CBM39 PF15886.5 GAN06557.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) cobW PF02492.19 GAN06557.1 - 0.081 12.5 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 GAN06557.1 - 0.12 12.8 0.0 0.45 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 GAN06557.1 - 0.13 12.5 0.1 3.7 7.9 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 GAN06557.1 - 0.19 12.0 0.4 0.33 11.2 0.4 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 GAN06558.1 - 5.7e-53 180.0 0.0 1e-51 175.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06558.1 - 2.6e-19 69.5 0.0 7.2e-19 68.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 GAN06558.1 - 0.0029 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAN06558.1 - 0.038 13.3 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like ARTD15_N PF18084.1 GAN06558.1 - 0.042 14.1 0.6 0.48 10.7 0.2 2.6 2 0 0 2 2 2 0 ARTD15 N-terminal domain RIO1 PF01163.22 GAN06558.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 GAN06558.1 - 0.049 12.4 0.0 0.082 11.7 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase AAA PF00004.29 GAN06559.1 - 1.3e-13 51.5 0.0 4.6e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAN06559.1 - 5.1e-13 49.5 0.0 2e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 GAN06559.1 - 2.9e-12 46.4 0.5 7e-12 45.2 0.5 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 GAN06559.1 - 2.5e-11 44.3 0.2 4e-10 40.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 GAN06559.1 - 2.3e-07 30.4 0.1 5.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial TniB protein NB-ARC PF00931.22 GAN06559.1 - 5.8e-06 25.7 0.1 1.3e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_lid_10 PF17872.1 GAN06559.1 - 9.9e-06 25.6 0.0 9.9e-06 25.6 0.0 3.2 3 1 1 4 4 4 1 AAA lid domain DUF2075 PF09848.9 GAN06559.1 - 3.8e-05 23.1 0.0 8.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 GAN06559.1 - 6.9e-05 22.9 0.1 0.00017 21.6 0.1 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 GAN06559.1 - 7.4e-05 22.7 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 GAN06559.1 - 0.00024 20.9 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN06559.1 - 0.00031 21.1 0.0 0.00074 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 GAN06559.1 - 0.00057 19.2 0.1 0.058 12.6 0.0 2.7 1 1 1 2 2 2 1 KAP family P-loop domain cobW PF02492.19 GAN06559.1 - 0.0071 15.9 0.3 0.025 14.2 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 GAN06559.1 - 0.0082 16.7 0.4 0.029 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAN06559.1 - 0.01 15.8 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2497 PF10691.9 GAN06559.1 - 0.013 15.9 0.3 0.058 13.8 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) AAA_11 PF13086.6 GAN06559.1 - 0.02 14.7 5.8 0.029 14.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAN06559.1 - 0.031 14.0 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 GAN06559.1 - 0.045 13.8 0.3 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAN06559.1 - 0.066 13.6 0.0 0.23 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 GAN06559.1 - 0.066 13.4 0.1 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 GAN06559.1 - 0.08 12.9 2.1 0.15 12.0 0.1 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit G-patch PF01585.23 GAN06561.1 - 7.1e-11 41.8 2.2 1.7e-10 40.6 2.1 1.7 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN06561.1 - 0.091 12.9 3.0 0.17 12.0 0.1 2.7 3 0 0 3 3 3 0 G-patch domain ADIP PF11559.8 GAN06561.1 - 2.9 8.0 20.9 6.7 6.8 20.9 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Amidohydro_1 PF01979.20 GAN06562.1 - 7.8e-20 71.5 0.0 4.2e-19 69.1 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAN06562.1 - 1.6e-11 44.4 0.4 7.5e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family ALG3 PF05208.13 GAN06563.1 - 4.1e-140 467.3 22.9 5.1e-140 467.0 22.9 1.1 1 0 0 1 1 1 1 ALG3 protein HSP70 PF00012.20 GAN06565.1 - 1e-07 30.6 0.1 1.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Hsp70 protein Prp19 PF08606.11 GAN06565.1 - 0.063 13.3 2.9 2.2 8.3 0.0 3.2 3 0 0 3 3 3 0 Prp19/Pso4-like Peptidase_C8 PF03569.13 GAN06565.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C8 SAC3_GANP PF03399.16 GAN06566.1 - 7.8e-25 87.8 4.7 2e-14 53.7 0.5 2.3 1 1 1 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAN06566.1 - 0.0017 18.3 1.2 0.0039 17.2 0.2 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family COX5A PF02284.16 GAN06566.1 - 0.0096 15.9 0.1 0.027 14.5 0.1 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va HOASN PF14515.6 GAN06566.1 - 0.6 10.5 5.0 0.76 10.2 0.0 2.8 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices HopW1-1 PF15457.6 GAN06567.1 - 0.0088 15.3 1.0 0.0088 15.3 1.0 2.0 2 0 0 2 2 2 1 Type III T3SS secreted effector HopW1-1/HopPmaA LIM PF00412.22 GAN06568.1 - 1.7e-18 66.6 32.4 5.6e-07 29.7 3.2 4.7 4 1 0 4 4 4 3 LIM domain Homeodomain PF00046.29 GAN06568.1 - 2.8e-12 46.3 1.6 1.3e-11 44.2 1.6 2.1 2 0 0 2 2 2 1 Homeodomain RRM_1 PF00076.22 GAN06569.1 - 1.1e-14 54.0 0.0 2.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_34 PF13601.6 GAN06569.1 - 0.042 14.0 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain TPR_MLP1_2 PF07926.12 GAN06570.1 - 0.015 15.4 1.9 0.015 15.4 1.9 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 GAN06570.1 - 5.4 5.4 5.4 11 4.4 5.4 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Thiolase_N PF00108.23 GAN06571.1 - 8.3e-97 323.6 5.0 1.1e-96 323.1 5.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN06571.1 - 8.9e-42 141.6 2.2 4.1e-41 139.5 0.3 2.6 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAN06571.1 - 6.7e-07 29.1 3.3 3.2e-05 23.6 0.8 2.8 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAN06571.1 - 0.087 12.7 5.0 0.27 11.1 0.2 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acetyltransf_1 PF00583.25 GAN06572.1 - 1.4e-06 28.5 0.0 3.4e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN06572.1 - 0.036 14.5 0.0 8.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SUR7 PF06687.12 GAN06573.1 - 0.00017 21.3 13.2 0.00029 20.5 13.2 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF973 PF06157.11 GAN06573.1 - 0.0025 16.9 0.9 0.0029 16.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Bax1-I PF01027.20 GAN06573.1 - 0.079 12.8 13.2 0.1 12.4 13.2 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MIG-14_Wnt-bd PF06664.12 GAN06573.1 - 0.12 11.5 7.2 0.16 11.2 7.2 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Tmemb_55A PF09788.9 GAN06573.1 - 1.1 8.3 3.0 1.6 7.8 3.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A DUF4234 PF14018.6 GAN06573.1 - 3.5 7.8 6.3 1.2 9.4 3.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Zn_clus PF00172.18 GAN06575.1 - 8.6e-06 25.8 8.3 1.6e-05 24.9 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAN06575.1 - 0.086 12.9 0.4 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 PAS fold DUF104 PF01954.16 GAN06575.1 - 0.16 12.4 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 RAP1 PF07218.11 GAN06575.1 - 0.17 10.1 7.6 0.24 9.7 7.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MBF1 PF08523.10 GAN06575.1 - 0.29 11.6 0.0 0.29 11.6 0.0 2.8 3 0 0 3 3 3 0 Multiprotein bridging factor 1 Alpha_GJ PF03229.13 GAN06575.1 - 0.45 11.1 8.2 0.06 13.9 2.0 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Macoilin PF09726.9 GAN06575.1 - 3.2 6.2 11.5 4.6 5.7 11.5 1.3 1 0 0 1 1 1 0 Macoilin family FDF PF09532.10 GAN06575.1 - 6.5 7.7 8.7 1.9 9.4 0.1 2.8 3 0 0 3 3 3 0 FDF domain ING PF12998.7 GAN06576.1 - 7.3e-14 52.2 2.3 7.3e-14 52.2 2.3 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAN06576.1 - 1.2e-05 25.0 10.2 2.1e-05 24.3 10.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAN06576.1 - 0.0063 16.7 2.3 0.017 15.4 2.3 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 GAN06576.1 - 0.019 14.5 3.2 0.038 13.5 3.2 1.5 1 0 0 1 1 1 0 PHD-finger UFC1 PF08694.11 GAN06576.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 MatE PF01554.18 GAN06577.1 - 9e-60 201.0 26.5 7.8e-33 113.4 10.4 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAN06577.1 - 1.9e-05 24.8 10.2 1.9e-05 24.8 10.2 3.9 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 GAN06577.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA PF00004.29 GAN06580.1 - 4.7e-38 130.6 0.0 9e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN06580.1 - 8.5e-10 38.3 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAN06580.1 - 1.3e-06 28.8 0.5 0.0055 17.0 0.1 3.2 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 GAN06580.1 - 2e-06 28.3 0.2 1.2e-05 25.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAN06580.1 - 3.4e-06 27.1 0.1 1.6e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAN06580.1 - 4.9e-06 26.4 0.0 1.5e-05 24.8 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAN06580.1 - 5.9e-06 26.4 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAN06580.1 - 3.4e-05 24.0 0.0 0.0001 22.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 GAN06580.1 - 7.4e-05 22.2 0.1 0.49 9.8 0.0 3.2 3 1 1 4 4 4 2 Bacterial TniB protein AAA_33 PF13671.6 GAN06580.1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAN06580.1 - 0.00031 21.3 0.0 0.00065 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAN06580.1 - 0.00071 19.0 0.2 0.0016 17.8 0.2 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAN06580.1 - 0.00085 19.3 0.1 0.0021 18.0 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 GAN06580.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 GAN06580.1 - 0.0017 18.3 0.1 0.012 15.6 0.0 2.3 1 1 1 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 GAN06580.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Guanylate_kin PF00625.21 GAN06580.1 - 0.003 17.3 0.1 0.075 12.7 0.0 2.8 2 1 2 4 4 4 1 Guanylate kinase ABC_tran PF00005.27 GAN06580.1 - 0.0033 18.0 0.0 0.0083 16.6 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 GAN06580.1 - 0.004 16.9 0.1 0.0074 16.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAN06580.1 - 0.0042 16.3 0.0 0.0081 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 GAN06580.1 - 0.0047 17.2 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 GAN06580.1 - 0.0092 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 GAN06580.1 - 0.0099 15.2 0.0 0.16 11.3 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.6 GAN06580.1 - 0.011 15.3 0.3 0.059 12.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 GAN06580.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 GAN06580.1 - 0.012 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 GAN06580.1 - 0.015 15.2 0.0 0.063 13.2 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 GAN06580.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_17 PF13207.6 GAN06580.1 - 0.017 15.5 0.1 0.045 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAN06580.1 - 0.03 13.9 0.2 0.078 12.5 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 GAN06580.1 - 0.036 13.9 0.1 2.6 7.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Parvo_NS1 PF01057.17 GAN06580.1 - 0.037 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 GAN06580.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 GAN06580.1 - 0.041 13.6 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAN06580.1 - 0.052 12.8 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 GAN06580.1 - 0.052 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA_lig_kinase PF08303.11 GAN06580.1 - 0.063 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain CPT PF07931.12 GAN06580.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Hydin_ADK PF17213.3 GAN06580.1 - 0.13 12.6 0.2 0.88 9.8 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF4449 PF14613.6 GAN06581.1 - 4e-11 43.3 4.4 4e-11 43.3 4.4 3.9 5 1 0 5 5 5 1 Protein of unknown function (DUF4449) PRD PF00874.20 GAN06581.1 - 1.9 8.8 5.6 0.39 11.0 0.5 2.5 2 0 0 2 2 2 0 PRD domain TCO89 PF10452.9 GAN06582.1 - 5.1e-08 32.4 5.0 6.5e-08 32.0 5.0 1.3 1 0 0 1 1 1 1 TORC1 subunit TCO89 AP_endonuc_2_N PF07582.12 GAN06582.1 - 0.009 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus WD40 PF00400.32 GAN06584.1 - 3.4e-40 135.3 19.2 8.5e-09 35.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06584.1 - 1.9e-14 53.7 0.0 0.0007 19.8 0.1 5.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN06584.1 - 0.0002 20.8 0.0 0.069 12.5 0.0 3.1 2 1 2 4 4 4 2 WD40-like domain eIF2A PF08662.11 GAN06584.1 - 0.00033 20.6 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN06584.1 - 0.0073 15.3 1.4 0.76 8.7 0.3 3.6 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Phage_GP20 PF06810.11 GAN06584.1 - 0.022 14.6 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Nup160 PF11715.8 GAN06584.1 - 0.12 10.9 0.2 5.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 RicinB_lectin_2 PF14200.6 GAN06585.1 - 2.6e-26 92.2 0.1 6.3e-11 42.9 0.0 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN06585.1 - 2.8e-12 47.0 0.0 1.7e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CCDC92 PF14916.6 GAN06586.1 - 0.061 13.1 2.1 0.15 11.9 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Lipase_3 PF01764.25 GAN06587.1 - 1e-17 64.3 0.0 5.2e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF3786 PF12654.7 GAN06587.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) PEPcase_2 PF14010.6 GAN06587.1 - 0.16 10.4 0.6 0.25 9.8 0.6 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RRM_1 PF00076.22 GAN06588.1 - 1.3e-35 121.0 0.0 3.3e-18 65.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAN06588.1 - 4.7e-13 49.1 2.8 2.1e-10 40.6 0.7 2.5 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAN06588.1 - 0.00016 21.3 0.1 0.16 11.6 0.0 2.7 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 GAN06588.1 - 0.008 15.8 0.0 0.06 13.0 0.0 2.4 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated MgtE PF01769.16 GAN06590.1 - 3.5e-43 146.9 27.5 2.7e-22 79.5 5.6 3.4 4 0 0 4 4 4 2 Divalent cation transporter MWFE PF15879.5 GAN06590.1 - 0.061 13.5 1.7 13 6.1 0.1 3.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit Tox-MPTase3 PF15639.6 GAN06590.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 3 NEMP PF10225.9 GAN06590.1 - 4.4 6.9 11.2 3.1 7.4 5.2 2.4 1 1 0 2 2 2 0 NEMP family BCDHK_Adom3 PF10436.9 GAN06591.1 - 1.2e-43 148.7 0.0 1.9e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAN06591.1 - 8.5e-12 45.6 0.2 7.3e-11 42.6 0.2 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAN06591.1 - 6.8e-08 32.4 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAN06591.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain FAD_binding_3 PF01494.19 GAN06592.1 - 1.3e-18 67.4 0.1 1e-16 61.1 0.1 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAN06592.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAN06592.1 - 0.0085 15.0 0.0 0.045 12.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAN06592.1 - 0.031 13.5 0.0 7.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN06592.1 - 0.095 13.3 0.0 6 7.5 0.0 3.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN06592.1 - 0.2 11.2 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase IBR PF01485.21 GAN06593.1 - 5.5e-24 84.2 49.5 5.8e-13 48.9 7.7 4.5 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GAN06593.1 - 5e-05 23.2 34.7 0.0012 18.8 5.6 4.1 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 GAN06593.1 - 5.7e-05 22.9 39.6 0.00031 20.5 5.8 4.3 3 1 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN06593.1 - 0.00011 22.4 45.2 0.0034 17.7 7.4 3.8 3 1 1 4 4 4 3 Ring finger domain zf-RING_5 PF14634.6 GAN06593.1 - 0.0038 17.1 42.8 0.0052 16.7 8.5 3.4 3 0 0 3 3 3 3 zinc-RING finger domain DUF3685 PF12452.8 GAN06593.1 - 0.097 12.4 1.0 0.19 11.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) zf-C3HC4_2 PF13923.6 GAN06593.1 - 0.19 11.6 41.7 0.051 13.4 5.4 4.9 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAN06593.1 - 0.88 9.8 38.4 0.085 13.0 5.7 4.9 3 2 1 4 4 4 0 zinc finger of C3HC4-type, RING DUF3824 PF12868.7 GAN06594.1 - 2e-14 54.5 29.4 0.043 14.5 2.3 7.6 7 0 0 7 7 7 7 Domain of unknwon function (DUF3824) Rick_17kDa_Anti PF05433.15 GAN06594.1 - 1.1 9.2 42.9 4.7 7.2 0.5 7.4 7 0 0 7 7 7 0 Glycine zipper 2TM domain ABA_WDS PF02496.16 GAN06594.1 - 3.6 8.1 50.5 0.48 10.9 4.4 7.5 7 0 0 7 7 7 0 ABA/WDS induced protein O-FucT PF10250.9 GAN06595.1 - 3.7e-10 40.0 1.2 8.2e-09 35.6 1.2 2.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Casc1 PF12366.8 GAN06595.1 - 0.024 14.2 0.2 0.042 13.4 0.2 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Cornichon PF03311.14 GAN06596.1 - 1.7e-45 154.3 5.9 3.3e-45 153.3 5.0 1.8 2 0 0 2 2 2 1 Cornichon protein CSN8_PSD8_EIF3K PF10075.9 GAN06596.1 - 1.1e-29 103.2 0.7 1.1e-29 103.2 0.7 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 GAN06596.1 - 6.5e-05 22.5 0.3 0.0001 21.8 0.3 1.3 1 0 0 1 1 1 1 SAC3/GANP family SNARE_assoc PF09335.11 GAN06598.1 - 1.2e-18 67.7 6.6 2.6e-18 66.6 5.0 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein ADH_N PF08240.12 GAN06599.1 - 6.8e-29 100.0 1.8 1.1e-28 99.3 1.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN06599.1 - 8.8e-27 93.6 0.0 1.4e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAN06599.1 - 1.2e-10 41.3 0.7 1.9e-09 37.4 0.7 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Inositol_P PF00459.25 GAN06600.1 - 3e-57 194.2 0.3 7.2e-57 193.0 0.3 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family DEAD_2 PF06733.15 GAN06600.1 - 1.6e-54 184.2 0.1 2.9e-54 183.3 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 GAN06600.1 - 1.1e-47 162.2 1.7 8.2e-44 149.6 0.4 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 GAN06600.1 - 5.8e-45 153.5 0.0 1.3e-44 152.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 GAN06600.1 - 0.00024 21.2 0.1 0.0051 16.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit G10 PF01125.17 GAN06600.1 - 0.017 14.9 0.3 0.04 13.7 0.3 1.6 1 0 0 1 1 1 0 G10 protein PhoH PF02562.16 GAN06600.1 - 0.043 13.3 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 GAN06600.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab_N PF02874.23 GAN06601.1 - 5.3e-24 84.5 1.7 1e-23 83.6 1.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 GAN06601.1 - 2.1e-15 57.0 0.2 3.8e-15 56.1 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 GAN06601.1 - 0.0043 16.3 0.1 0.0063 15.7 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 GAN06601.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 GAN06601.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 GAN06601.1 - 0.021 15.2 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 GAN06601.1 - 0.038 13.3 0.4 0.063 12.6 0.4 1.3 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 GAN06601.1 - 0.051 13.5 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAN06601.1 - 0.06 13.7 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAN06601.1 - 0.081 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 GAN06601.1 - 0.12 11.3 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 GAN06601.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAN06601.1 - 0.13 12.8 0.2 0.32 11.5 0.2 1.6 1 0 0 1 1 1 0 ABC transporter CSD2 PF17876.1 GAN06601.1 - 0.14 12.4 0.6 0.5 10.6 0.4 2.0 2 0 0 2 2 2 0 Cold shock domain Roc PF08477.13 GAN06601.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RPA_interact_M PF14767.6 GAN06602.1 - 0.02 15.5 1.7 0.02 15.5 1.7 3.8 3 0 0 3 3 3 0 Replication protein A interacting middle Flavokinase PF01687.17 GAN06604.1 - 2.6e-36 124.3 0.0 3.3e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase DCX PF03607.17 GAN06604.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Doublecortin Glyco_hydro_31 PF01055.26 GAN06605.1 - 8e-60 203.2 1.9 1.2e-59 202.7 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAN06605.1 - 9.5e-05 22.6 0.1 0.00053 20.3 0.1 2.2 1 1 0 1 1 1 1 Galactose mutarotase-like DHBP_synthase PF00926.19 GAN06606.1 - 3e-84 281.3 0.1 3.4e-84 281.1 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase EPSP_synthase PF00275.20 GAN06607.1 - 3.8e-125 417.9 0.1 5.7e-125 417.3 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 GAN06607.1 - 6.9e-93 310.6 0.1 2e-92 309.1 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 GAN06607.1 - 9.4e-52 176.5 0.0 1.8e-51 175.6 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 GAN06607.1 - 1.9e-33 115.8 0.0 4.7e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 GAN06607.1 - 1.3e-24 86.2 0.1 6.2e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 GAN06607.1 - 7.7e-10 38.4 0.0 1.6e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 GAN06607.1 - 1.6e-07 31.4 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 GAN06607.1 - 4.7e-05 23.2 0.0 0.00016 21.5 0.0 2.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_18 PF13238.6 GAN06607.1 - 0.0057 17.2 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAN06607.1 - 0.017 14.3 0.2 0.059 12.5 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 GAN06607.1 - 0.017 15.3 0.0 0.056 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAN06607.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ntox28 PF15605.6 GAN06608.1 - 0.033 14.4 1.6 0.16 12.2 1.1 2.4 2 1 0 2 2 2 0 Bacterial toxin 28 PspB PF06667.12 GAN06608.1 - 0.14 12.2 3.5 2.7 8.1 0.4 3.0 2 0 0 2 2 2 0 Phage shock protein B Fer4_24 PF18109.1 GAN06608.1 - 0.18 12.1 1.1 1.7 9.0 0.3 2.4 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Phasin PF05597.11 GAN06608.1 - 0.27 11.2 4.9 0.53 10.3 1.0 2.7 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Laminin_II PF06009.12 GAN06608.1 - 0.53 10.3 6.2 0.32 11.0 3.0 2.2 2 0 0 2 2 2 0 Laminin Domain II Gly_transf_sug PF04488.15 GAN06609.1 - 1e-07 32.5 0.3 2.5e-07 31.2 0.3 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAN06609.1 - 0.028 13.8 3.6 0.073 12.4 3.6 1.8 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 GAN06609.1 - 0.085 12.1 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain RVT_1 PF00078.27 GAN06610.1 - 9.7e-27 93.9 0.0 1.2e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GATA PF00320.27 GAN06611.1 - 1.5e-11 43.7 13.2 5.4e-10 38.7 2.5 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN06611.1 - 0.088 12.3 0.4 0.088 12.3 0.4 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 GAN06611.1 - 0.26 11.2 14.1 1.9 8.5 2.2 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ctf8 PF09696.10 GAN06612.1 - 2.6e-08 34.3 0.1 8.4e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 Ctf8 Vps54 PF07928.12 GAN06613.1 - 1e-50 171.6 1.5 1e-50 171.6 1.5 2.0 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 GAN06613.1 - 1.7e-11 44.0 0.5 4.1e-11 42.7 0.1 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 GAN06613.1 - 0.00044 20.1 0.5 0.00044 20.1 0.5 2.3 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF1515 PF07439.11 GAN06613.1 - 0.21 11.6 0.7 0.8 9.7 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) PSP1 PF04468.12 GAN06614.1 - 4.9e-33 113.3 2.0 4.9e-33 113.3 2.0 2.5 3 0 0 3 3 3 1 PSP1 C-terminal conserved region Peptidase_S49_N PF08496.10 GAN06614.1 - 0.93 9.6 6.4 7.7 6.6 1.4 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SIR2 PF02146.17 GAN06615.1 - 7e-31 107.5 0.0 9.3e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF547 PF04784.14 GAN06615.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF547 JmjC PF02373.22 GAN06616.1 - 4e-42 143.2 1.0 1.2e-41 141.7 1.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 GAN06616.1 - 7.1e-25 87.9 5.4 3.3e-23 82.4 4.9 2.2 2 0 0 2 2 2 1 PLU-1-like protein ARID PF01388.21 GAN06616.1 - 3.5e-20 72.5 0.1 1e-19 71.0 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 GAN06616.1 - 3.7e-19 68.4 28.7 1.4e-12 47.3 5.9 3.1 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 GAN06616.1 - 3.5e-11 43.3 15.3 3.5e-11 43.3 15.3 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger JmjN PF02375.17 GAN06616.1 - 2.6e-10 40.1 0.6 9.8e-10 38.2 0.6 2.0 1 0 0 1 1 1 1 jmjN domain zf-PHD-like PF15446.6 GAN06616.1 - 0.017 14.8 10.7 0.068 12.8 1.9 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain E2F_TDP PF02319.20 GAN06617.1 - 7.3e-25 86.8 0.2 1.7e-24 85.6 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 GAN06617.1 - 2.7e-06 27.6 4.9 6.7e-06 26.4 2.5 2.3 1 1 1 2 2 2 1 E2F transcription factor CC-MB domain Wtap PF17098.5 GAN06617.1 - 0.014 15.3 0.5 0.014 15.3 0.5 2.6 3 1 0 3 3 3 0 WTAP/Mum2p family TrmB PF01978.19 GAN06617.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 GAN06617.1 - 0.13 12.4 0.8 0.53 10.5 0.8 2.1 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC bZIP_2 PF07716.15 GAN06617.1 - 2.7 8.1 10.6 0.18 11.9 2.5 2.8 3 0 0 3 3 3 0 Basic region leucine zipper DUF3439 PF11921.8 GAN06618.1 - 1.3e-05 25.1 0.1 2.4e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 GAN06618.1 - 0.0033 17.4 4.0 0.0045 17.0 4.0 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein 7tm_6 PF02949.20 GAN06618.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 7tm Odorant receptor Mrpl_C PF18502.1 GAN06618.1 - 0.021 15.1 1.9 0.037 14.3 1.4 1.6 1 1 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Ric8 PF10165.9 GAN06618.1 - 0.023 13.8 4.3 0.027 13.5 4.3 1.0 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn CHAD PF05235.14 GAN06618.1 - 0.075 13.0 0.8 0.15 12.0 0.8 1.5 1 1 0 1 1 1 0 CHAD domain SSP160 PF06933.11 GAN06618.1 - 5 5.2 9.3 6.8 4.8 9.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RCC1 PF00415.18 GAN06619.1 - 1.2e-49 166.7 7.4 3.2e-09 37.3 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAN06619.1 - 8e-30 102.0 25.9 5.9e-06 25.9 0.0 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_M49 PF03571.15 GAN06620.1 - 2.1e-09 36.3 0.2 2e-07 29.8 0.1 2.2 1 1 1 2 2 2 2 Peptidase family M49 MPTase-PolyVal PF18818.1 GAN06620.1 - 0.00077 19.5 1.8 0.0011 19.0 0.5 2.0 2 0 0 2 2 2 1 Metallopeptidase superfamily domain Rib_recp_KP_reg PF05104.12 GAN06621.1 - 0.1 13.6 3.7 0.21 12.7 3.7 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Pkinase PF00069.25 GAN06622.1 - 2.2e-77 260.0 0.0 2.9e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06622.1 - 1.8e-39 135.6 0.0 2.4e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN06622.1 - 3.3e-08 33.2 0.0 0.00027 20.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 GAN06622.1 - 1.5e-05 25.1 0.1 0.17 11.8 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAN06622.1 - 3.4e-05 23.5 0.7 0.00033 20.3 0.7 2.1 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAN06622.1 - 0.00051 19.5 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN06622.1 - 0.0043 16.0 0.1 0.0043 16.0 0.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 GAN06622.1 - 0.018 14.1 1.0 0.024 13.6 0.2 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 GAN06622.1 - 0.04 13.4 0.1 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 GAN06622.1 - 0.051 13.2 0.5 9.9 5.7 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Mito_carr PF00153.27 GAN06623.1 - 1.8e-61 204.1 5.6 1.3e-20 73.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN06623.1 - 0.0022 17.2 0.4 0.2 10.8 0.0 3.0 4 0 0 4 4 4 2 Gammaproteobacterial serine protease Xpo1 PF08389.12 GAN06624.1 - 0.0061 16.6 0.1 0.1 12.7 0.1 3.2 2 0 0 2 2 2 1 Exportin 1-like protein TPR_1 PF00515.28 GAN06625.1 - 4.3e-51 168.7 33.1 4.9e-08 32.5 0.1 10.6 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAN06625.1 - 5.5e-46 151.0 26.5 3.2e-06 26.8 0.0 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAN06625.1 - 1.5e-31 106.0 25.3 7.3e-06 25.8 0.0 10.1 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06625.1 - 1.7e-24 86.1 12.8 4.5e-05 23.9 0.1 6.9 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAN06625.1 - 2.3e-24 84.0 23.2 0.00061 20.0 0.1 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAN06625.1 - 2.8e-24 83.7 13.1 0.00028 21.4 0.0 9.1 3 2 7 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAN06625.1 - 5.6e-24 84.5 13.1 4.1e-05 24.1 0.7 7.0 3 3 5 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAN06625.1 - 1.8e-23 82.6 24.0 0.00023 21.4 0.4 7.2 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAN06625.1 - 2.1e-23 81.7 34.7 3.7e-05 23.3 1.5 9.5 4 2 5 9 9 9 6 TPR repeat TPR_7 PF13176.6 GAN06625.1 - 3.6e-18 64.2 18.5 0.064 13.3 0.1 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAN06625.1 - 8.8e-18 63.7 22.5 0.0015 19.0 0.0 9.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAN06625.1 - 1.8e-17 63.2 12.8 0.00041 20.4 0.2 6.6 3 2 4 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN06625.1 - 5.5e-10 39.3 16.1 3.1e-07 30.5 2.2 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAN06625.1 - 6.5e-09 35.4 10.5 0.017 14.3 1.4 5.0 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_21 PF09976.9 GAN06625.1 - 0.00023 20.9 5.7 0.97 9.1 0.1 4.6 4 2 0 4 4 4 2 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 GAN06625.1 - 0.0012 18.6 6.7 0.55 9.9 0.1 2.9 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_MalT PF17874.1 GAN06625.1 - 0.0027 17.1 3.4 14 4.9 0.0 3.2 2 1 0 2 2 2 0 MalT-like TPR region TPR_20 PF14561.6 GAN06625.1 - 0.0032 17.8 0.4 10 6.6 0.0 4.6 3 2 2 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 GAN06625.1 - 0.0092 16.4 9.2 4.8 7.6 0.9 3.4 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 GAN06625.1 - 0.011 15.5 15.5 6.5 6.8 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat SNAP PF14938.6 GAN06625.1 - 0.076 12.4 16.4 1.2 8.5 2.3 4.5 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 GAN06625.1 - 0.5 9.3 3.6 3.9 6.4 0.1 2.8 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 GAN06625.1 - 3.6 7.7 27.6 3.6 7.7 0.5 6.9 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 GAN06625.1 - 5.2 6.8 5.6 23 4.6 0.0 3.9 3 2 2 5 5 5 0 26S proteasome subunit RPN7 DUF1751 PF08551.10 GAN06626.1 - 2.4e-27 95.4 3.9 2.4e-27 95.4 3.9 2.1 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GAN06626.1 - 5.5e-09 36.2 11.5 1.1e-08 35.2 11.5 1.5 1 0 0 1 1 1 1 Rhomboid family FA_desaturase PF00487.24 GAN06626.1 - 7.2 6.4 9.0 0.18 11.6 1.5 1.8 1 1 1 2 2 2 0 Fatty acid desaturase PPR_2 PF13041.6 GAN06627.1 - 2.3e-20 72.5 11.5 4.8e-05 23.5 0.1 7.5 7 1 2 9 9 9 4 PPR repeat family PPR_3 PF13812.6 GAN06627.1 - 1.5e-15 57.0 1.9 0.00014 21.9 0.0 6.2 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 GAN06627.1 - 2.2e-10 40.1 4.9 0.32 11.3 0.1 7.8 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.7 GAN06627.1 - 2.2e-07 30.4 0.0 0.057 13.1 0.0 5.6 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 GAN06627.1 - 2.6e-05 23.7 10.8 0.09 12.1 0.1 4.9 3 1 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP Wzy_C_2 PF11846.8 GAN06627.1 - 0.0027 17.7 1.1 0.13 12.2 0.0 2.8 2 1 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal Clathrin PF00637.20 GAN06627.1 - 0.0082 16.0 4.7 0.73 9.7 0.0 4.2 4 0 0 4 4 4 1 Region in Clathrin and VPS YebG PF07130.12 GAN06627.1 - 0.04 13.8 1.3 6.4 6.7 0.1 3.2 2 0 0 2 2 2 0 YebG protein FeoC PF09012.10 GAN06627.1 - 0.091 12.8 0.3 4.2 7.5 0.1 3.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator RapH_N PF18801.1 GAN06627.1 - 0.11 12.6 0.7 2 8.6 0.0 3.0 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Cyclin PF08613.11 GAN06628.1 - 2.9e-11 44.0 0.1 4.2e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN06628.1 - 3.8e-06 26.7 0.0 6.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4536 PF15055.6 GAN06628.1 - 0.01 16.0 0.3 0.81 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Cue1_U7BR PF18499.1 GAN06628.1 - 0.016 15.3 2.8 1.3 9.1 0.2 3.0 3 0 0 3 3 3 0 Ubc7p-binding region of Cue1 NRBF2 PF08961.10 GAN06629.1 - 0.0012 18.5 0.9 0.0012 18.5 0.9 3.2 2 1 1 3 3 3 2 Nuclear receptor-binding factor 2, autophagy regulator FKS1_dom1 PF14288.6 GAN06629.1 - 0.11 12.9 1.5 0.25 11.7 0.1 2.3 1 1 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Cep57_MT_bd PF06657.13 GAN06629.1 - 0.13 12.7 12.3 0.18 12.3 2.3 3.8 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 bZIP_1 PF00170.21 GAN06629.1 - 3.5 7.8 12.1 6.6 6.9 0.4 4.0 2 2 2 4 4 4 0 bZIP transcription factor RhoGEF PF00621.20 GAN06630.1 - 4e-21 76.1 1.7 1.1e-20 74.7 1.7 1.8 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 GAN06630.1 - 5.1e-20 72.2 0.0 1.5e-19 70.7 0.0 1.8 1 1 0 1 1 1 1 CNH domain PH_5 PF15405.6 GAN06630.1 - 0.0012 19.0 0.0 0.0041 17.2 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_4 PF12763.7 GAN06631.1 - 4e-26 91.0 0.0 8.2e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.6 GAN06631.1 - 1.3e-25 89.0 1.7 6.1e-12 45.2 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAN06631.1 - 1.9e-25 88.2 1.7 5.9e-12 45.0 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAN06631.1 - 2.3e-16 59.2 0.0 1.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 GAN06631.1 - 1.7e-10 40.4 0.4 4.9e-10 38.9 0.4 1.9 1 0 0 1 1 1 1 WH2 motif EF-hand_6 PF13405.6 GAN06631.1 - 0.025 14.5 0.1 4.8 7.4 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 GAN06631.1 - 0.028 14.8 0.1 1 9.8 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.32 GAN06631.1 - 0.064 12.8 0.2 0.24 11.1 0.1 2.1 2 0 0 2 2 2 0 EF hand SH3_3 PF08239.11 GAN06631.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Macoilin PF09726.9 GAN06632.1 - 2.6 6.5 5.0 3.4 6.1 5.0 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 GAN06632.1 - 4.2 5.5 6.0 5.2 5.2 6.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4211 PF13926.6 GAN06633.1 - 0.031 14.3 0.4 0.04 14.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) IZUMO PF15005.6 GAN06633.1 - 0.59 10.6 6.8 1 9.8 6.0 1.7 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Syntaxin-6_N PF09177.11 GAN06633.1 - 0.77 10.4 6.2 1.3 9.6 6.1 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Methyltransf_3 PF01596.17 GAN06634.1 - 1.3e-46 158.5 0.2 1.1e-45 155.4 0.2 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAN06634.1 - 4.7e-09 37.2 0.0 1.3e-08 35.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAN06634.1 - 3.3e-05 23.7 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAN06634.1 - 0.00025 20.9 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN06634.1 - 0.018 15.8 0.0 0.049 14.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 GAN06634.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 GAN06634.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CmcI PF04989.12 GAN06634.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase adh_short PF00106.25 GAN06635.1 - 1.7e-39 135.4 9.0 8.9e-34 116.7 3.1 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAN06635.1 - 2e-34 119.2 9.5 2.1e-32 112.6 9.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN06635.1 - 2.3e-08 34.2 6.6 1.5e-07 31.5 6.6 2.1 1 1 0 1 1 1 1 KR domain LytR_C PF13399.6 GAN06635.1 - 0.024 15.6 3.6 0.083 13.9 1.9 2.4 2 1 1 3 3 3 0 LytR cell envelope-related transcriptional attenuator HK PF02110.15 GAN06636.1 - 7.8e-80 267.8 6.0 7.8e-80 267.8 6.0 1.8 1 1 1 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 GAN06636.1 - 1.5e-62 210.1 0.4 7.6e-62 207.9 0.1 2.0 2 0 0 2 2 2 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 GAN06636.1 - 1.9e-05 24.2 3.0 1.9e-05 24.2 3.0 1.6 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 GAN06636.1 - 0.00069 19.1 0.3 0.0015 17.9 0.1 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HECT PF00632.25 GAN06637.1 - 1.2e-93 314.0 0.0 2.7e-93 312.8 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 GAN06637.1 - 6e-69 232.8 2.9 6e-69 232.8 2.9 6.5 5 3 0 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 GAN06637.1 - 2e-60 205.1 11.6 1.2e-38 133.5 2.3 5.1 5 1 1 6 6 6 2 Domain of Unknown Function (DUF908) UBM PF14377.6 GAN06637.1 - 1.1e-18 66.0 9.1 4.6e-09 35.4 0.7 3.0 2 0 0 2 2 2 2 Ubiquitin binding region DUF2335 PF10097.9 GAN06637.1 - 0.013 15.4 0.1 0.061 13.3 0.1 2.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Glyco_hydro_38 PF18438.1 GAN06637.1 - 0.017 15.2 0.3 0.041 13.9 0.3 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 UBA PF00627.31 GAN06637.1 - 0.091 12.7 0.6 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Sde2_N_Ubi PF13019.6 GAN06638.1 - 2.7e-33 115.1 0.4 2.7e-33 115.1 0.4 1.8 2 1 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain UPF0147 PF03685.13 GAN06638.1 - 0.062 13.4 0.7 0.28 11.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) ubiquitin PF00240.23 GAN06638.1 - 0.13 12.0 2.7 0.39 10.5 0.0 2.7 2 1 1 3 3 3 0 Ubiquitin family Myc_N PF01056.18 GAN06638.1 - 0.24 11.3 9.0 0.34 10.7 9.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Med8 PF10232.9 GAN06638.1 - 2.3 7.7 10.8 4.3 6.9 10.8 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF2407 PF10302.9 GAN06638.1 - 7.6 7.1 8.4 52 4.5 2.4 3.2 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Spectrin_like PF18373.1 GAN06639.1 - 0.035 14.2 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Spectrin like domain Tim54 PF11711.8 GAN06640.1 - 0.014 14.3 4.6 0.022 13.6 4.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 GAN06640.1 - 0.2 9.8 14.1 0.28 9.3 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAN06640.1 - 0.44 9.9 13.2 0.69 9.3 13.2 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GAN06640.1 - 0.55 8.3 12.4 0.82 7.7 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 GAN06640.1 - 0.61 9.0 12.6 0.78 8.7 11.4 1.7 2 0 0 2 2 2 0 Paf1 CDC45 PF02724.14 GAN06640.1 - 1.2 7.3 10.5 1.9 6.7 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GAN06640.1 - 1.7 7.9 12.8 2.8 7.2 12.8 1.3 1 0 0 1 1 1 0 BUD22 DUF5523 PF17661.1 GAN06640.1 - 2.3 7.8 10.3 4.3 7.0 10.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) TRAP_alpha PF03896.16 GAN06640.1 - 3 7.0 8.7 5.7 6.1 8.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit XRCC4 PF06632.12 GAN06640.1 - 3.1 6.6 13.3 5.5 5.7 13.3 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PI3K_1B_p101 PF10486.9 GAN06640.1 - 3.9 5.1 9.2 5.5 4.6 9.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SCIMP PF15050.6 GAN06641.1 - 0.0086 16.5 1.3 0.02 15.4 1.3 1.7 1 0 0 1 1 1 1 SCIMP protein SPX PF03105.19 GAN06641.1 - 2.7 7.8 22.5 3.5 7.4 22.5 1.2 1 0 0 1 1 1 0 SPX domain Aa_trans PF01490.18 GAN06642.1 - 4.4e-78 262.8 37.4 5.4e-78 262.5 37.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 GAN06642.1 - 0.00021 20.3 23.9 0.00021 20.3 23.9 1.9 2 0 0 2 2 2 1 Spore germination protein HABP4_PAI-RBP1 PF04774.15 GAN06643.1 - 0.0002 22.2 1.4 0.00025 21.9 1.2 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family HABP4_PAI-RBP1 PF04774.15 GAN06644.1 - 0.0039 18.0 0.2 0.0041 17.9 0.2 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family SHR3_chaperone PF08229.11 GAN06646.1 - 4.9e-40 136.5 0.0 5.5e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Glt_symporter PF03616.14 GAN06646.1 - 0.002 16.9 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 Sodium/glutamate symporter Radial_spoke PF04712.12 GAN06646.1 - 0.011 14.7 0.6 0.015 14.3 0.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4383 PF14325.6 GAN06646.1 - 0.016 15.5 2.3 0.022 15.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) FAM176 PF14851.6 GAN06646.1 - 0.041 13.6 0.7 0.052 13.2 0.7 1.2 1 0 0 1 1 1 0 FAM176 family Rhabdo_ncap PF00945.18 GAN06646.1 - 0.079 11.8 0.3 0.095 11.6 0.3 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein NOA36 PF06524.12 GAN06646.1 - 1.4 8.1 8.6 1.8 7.8 8.6 1.1 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 GAN06646.1 - 2.3 7.3 7.3 3.4 6.8 5.0 1.9 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FUSC_2 PF13515.6 GAN06647.1 - 1.2e-19 70.6 10.4 1.2e-19 70.6 10.4 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAN06647.1 - 3.7e-10 39.0 8.8 3.7e-10 39.0 8.8 3.5 2 2 2 5 5 5 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 GAN06647.1 - 7.3e-10 39.1 0.3 4.9e-09 36.4 0.1 2.4 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 GAN06647.1 - 1.3e-09 37.4 4.9 1.3e-09 37.4 4.9 3.5 3 1 0 3 3 3 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 GAN06647.1 - 3.5e-06 26.3 0.2 3.5e-06 26.3 0.2 3.2 2 1 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_1 PF06081.11 GAN06647.1 - 0.0048 17.0 5.5 0.017 15.3 5.5 2.0 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 MARVEL PF01284.23 GAN06647.1 - 7 6.7 26.7 0.5 10.4 14.5 3.2 2 1 0 3 3 3 0 Membrane-associating domain Peptidase_M16_C PF05193.21 GAN06648.1 - 7e-36 124.0 0.1 1.6e-35 122.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAN06648.1 - 6.9e-29 100.7 0.7 4.9e-28 98.0 0.2 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) MBOAT_2 PF13813.6 GAN06649.1 - 8.8e-11 41.9 3.8 8.8e-11 41.9 3.8 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family 4HBT_3 PF13622.6 GAN06650.1 - 5.4e-63 213.5 0.1 6.4e-63 213.3 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 GAN06650.1 - 5.2e-35 120.2 0.0 1.1e-26 93.3 0.0 3.1 2 1 1 3 3 3 2 Acyl-CoA thioesterase TAL_FSA PF00923.19 GAN06651.1 - 2.2e-100 335.7 0.2 2.5e-100 335.5 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Chitin_synth_1 PF01644.17 GAN06652.1 - 1.1e-73 246.6 0.0 1.7e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAN06652.1 - 3.9e-31 106.8 0.1 1e-30 105.5 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAN06652.1 - 1.9e-22 79.6 3.0 3.1e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN06652.1 - 3.6e-05 23.8 7.6 3.6e-05 23.8 7.6 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 OrfB_IS605 PF01385.19 GAN06652.1 - 0.019 15.2 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 Probable transposase PEPCK_ATP PF01293.20 GAN06653.1 - 1.5e-224 745.9 0.0 1.8e-224 745.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 GAN06653.1 - 0.044 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Nucleoporin_N PF08801.11 GAN06654.1 - 1.9e-17 63.1 0.1 4.6e-15 55.3 0.1 2.3 1 1 0 1 1 1 1 Nup133 N terminal like MFS_1 PF07690.16 GAN06656.1 - 1.2e-17 63.9 37.6 2e-17 63.2 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN06656.1 - 8.7e-07 27.8 6.1 8.7e-07 27.8 6.1 3.1 2 1 0 3 3 3 1 MFS/sugar transport protein TssN PF17555.2 GAN06656.1 - 0.0036 16.7 4.9 0.0036 16.7 4.9 3.6 2 2 3 5 5 5 1 Type VI secretion system, TssN Bactofilin PF04519.13 GAN06656.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal B-block_TFIIIC PF04182.12 GAN06657.1 - 1.1e-08 35.2 2.6 6e-07 29.5 0.1 3.9 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC DUF3617 PF12276.8 GAN06657.1 - 1.5 9.1 6.6 9.4 6.6 6.6 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) CRAL_TRIO PF00650.20 GAN06658.1 - 5.8e-32 110.6 0.0 8.4e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN06658.1 - 0.00079 19.6 0.2 0.0015 18.7 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAN06658.1 - 0.0024 18.0 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3543 PF12063.8 GAN06658.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Ribosomal_60s PF00428.19 GAN06659.1 - 6e-26 90.9 6.7 7.3e-26 90.6 6.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PHD PF00628.29 GAN06660.1 - 1.3e-10 41.0 8.2 3.4e-10 39.7 8.2 1.8 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 GAN06660.1 - 7.6e-06 25.9 4.2 7.6e-06 25.9 4.2 3.3 3 1 1 4 4 4 2 CpG binding protein zinc finger C terminal domain zf-RING_2 PF13639.6 GAN06660.1 - 0.24 11.8 7.0 0.71 10.3 7.0 1.8 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 GAN06660.1 - 0.7 9.5 7.6 0.046 13.3 2.0 2.0 2 0 0 2 2 2 0 PHD-finger PHD_3 PF13922.6 GAN06660.1 - 1.1 9.8 4.4 0.59 10.6 1.0 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Romo1 PF10247.9 GAN06661.1 - 0.048 14.0 0.1 0.07 13.5 0.1 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 AgrB PF04647.15 GAN06662.1 - 0.0021 17.4 4.1 0.0021 17.4 4.1 1.6 2 0 0 2 2 2 1 Accessory gene regulator B Tmpp129 PF10272.9 GAN06662.1 - 0.0045 16.3 1.9 0.006 15.9 1.9 1.1 1 0 0 1 1 1 1 Putative transmembrane protein precursor DUF4834 PF16118.5 GAN06662.1 - 0.057 14.4 0.2 0.057 14.4 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2976 PF11190.8 GAN06662.1 - 0.11 12.3 1.5 0.12 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Conotoxin PF02950.17 GAN06662.1 - 0.14 13.2 0.5 8 7.6 0.0 2.4 2 0 0 2 2 2 0 Conotoxin Baculo_11_kDa PF06143.11 GAN06662.1 - 2.6 7.7 10.1 0.57 9.8 4.7 2.3 1 1 1 2 2 2 0 Baculovirus 11 kDa family GMC_oxred_N PF00732.19 GAN06663.1 - 4.9e-57 193.6 0.0 7.3e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAN06663.1 - 2.4e-28 99.5 0.0 4.7e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAN06663.1 - 4.2e-06 26.1 0.1 0.00082 18.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 GAN06663.1 - 9.1e-05 21.8 3.4 0.076 12.3 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN06663.1 - 0.00014 22.0 0.2 0.00038 20.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN06663.1 - 0.00015 21.1 0.5 0.0024 17.2 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAN06663.1 - 0.00024 20.3 0.1 0.00037 19.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAN06663.1 - 0.0005 19.8 0.1 0.0017 18.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAN06663.1 - 0.0036 16.6 0.0 0.0069 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GAN06663.1 - 0.032 12.9 0.2 0.15 10.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein HHH PF00633.23 GAN06663.1 - 0.096 12.6 0.1 0.99 9.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4746 PF15928.5 GAN06664.1 - 0.58 9.5 6.0 0.68 9.3 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) eIF-3c_N PF05470.12 GAN06665.1 - 0.59 8.4 7.5 1.2 7.4 7.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Gluconate_2-dh3 PF13618.6 GAN06665.1 - 1.9 8.7 5.2 10 6.4 5.2 2.0 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 GDI PF00996.18 GAN06666.1 - 6.2e-51 173.3 0.3 7.6e-39 133.5 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor UPF0060 PF02694.15 GAN06666.1 - 0.22 11.8 0.1 0.55 10.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family YIF1 PF03878.15 GAN06667.1 - 5.6e-89 297.8 2.9 8.3e-89 297.2 2.9 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 GAN06667.1 - 0.0093 15.7 4.2 0.019 14.7 4.2 1.5 1 0 0 1 1 1 1 Yip1 domain Bud13 PF09736.9 GAN06667.1 - 0.14 12.5 2.2 0.21 12.0 2.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex TFIIA PF03153.13 GAN06667.1 - 0.2 11.6 20.6 0.26 11.3 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc7_N PF15402.6 GAN06667.1 - 7.7 4.6 9.4 9.7 4.3 9.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Acyl-CoA_dh_1 PF00441.24 GAN06668.1 - 1.4e-31 109.7 0.3 2.6e-31 108.9 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 GAN06668.1 - 5.7e-23 80.8 0.1 1e-22 80.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 GAN06668.1 - 1.9e-21 76.0 0.0 4e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAN06668.1 - 8.8e-18 65.0 0.0 2.1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAN06668.1 - 1.1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.32 GAN06669.1 - 2.1e-37 126.4 17.1 3.8e-06 27.5 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06669.1 - 3.6e-08 33.6 0.8 0.92 9.9 0.0 5.2 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAN06669.1 - 8.1e-05 22.4 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN06669.1 - 0.00051 19.9 0.1 0.0013 18.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like PQQ_3 PF13570.6 GAN06669.1 - 0.029 14.8 0.1 40 4.9 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain PALB2_WD40 PF16756.5 GAN06669.1 - 0.083 11.8 0.2 3.8 6.3 0.1 3.1 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Bap31 PF05529.12 GAN06670.1 - 1.2e-43 148.2 1.1 2e-43 147.5 1.1 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region EIF_2_alpha PF07541.12 GAN06670.1 - 1.5e-36 125.0 0.1 4.3e-36 123.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 GAN06670.1 - 4.6e-10 39.7 1.8 1.4e-09 38.1 1.8 1.8 1 0 0 1 1 1 1 S1 RNA binding domain Bap31_Bap29_C PF18035.1 GAN06670.1 - 1.4e-06 28.2 5.3 1.4e-06 28.2 5.3 2.9 3 0 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2065 PF09838.9 GAN06670.1 - 0.021 14.8 1.2 0.044 13.8 1.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) NPV_P10 PF05531.12 GAN06670.1 - 0.045 14.2 1.1 0.1 13.1 0.4 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Connexin PF00029.19 GAN06670.1 - 0.51 10.1 1.6 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Connexin Jnk-SapK_ap_N PF09744.9 GAN06670.1 - 1.4 9.1 18.5 0.23 11.7 12.0 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-CSL PF05207.13 GAN06671.1 - 1.4e-23 82.3 1.7 1.4e-23 82.3 1.7 1.5 2 0 0 2 2 2 1 CSL zinc finger zf-RING_7 PF02591.15 GAN06671.1 - 0.0055 16.9 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 C4-type zinc ribbon domain zf-RING_4 PF14570.6 GAN06671.1 - 0.027 14.3 0.8 0.056 13.3 0.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 GAN06671.1 - 0.031 14.2 1.0 0.051 13.5 0.4 1.6 2 0 0 2 2 2 0 zinc-ribbon domain RCC1 PF00415.18 GAN06672.1 - 1.4e-79 262.5 3.2 3.2e-11 43.7 0.1 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAN06672.1 - 5.2e-39 131.3 35.1 3.3e-07 29.9 0.0 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 GAN06672.1 - 2.8e-05 24.2 3.3 4.7 7.7 0.1 6.1 8 0 0 8 8 8 2 Kelch motif Hira PF07569.11 GAN06672.1 - 0.056 13.2 0.6 12 5.6 0.1 4.0 5 0 0 5 5 5 0 TUP1-like enhancer of split Kelch_2 PF07646.15 GAN06672.1 - 0.5 10.4 2.1 32 4.7 0.0 3.9 5 0 0 5 5 5 0 Kelch motif Gtr1_RagA PF04670.12 GAN06673.1 - 1e-71 241.0 0.9 1.6e-71 240.4 0.9 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAN06673.1 - 1.9e-06 27.5 1.2 2.1e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN06673.1 - 0.00012 22.1 0.0 0.00084 19.4 0.0 2.3 2 2 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 GAN06673.1 - 0.00012 21.7 0.2 0.0002 21.0 0.2 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAN06673.1 - 0.00017 21.1 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAN06673.1 - 0.00024 21.3 0.1 0.00076 19.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAN06673.1 - 0.001 18.7 0.2 0.0028 17.2 0.0 1.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain WD40 PF00400.32 GAN06674.1 - 0.00052 20.8 0.1 0.78 10.7 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06674.1 - 0.0052 17.0 0.0 14 6.0 0.0 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Clathrin_propel PF01394.20 GAN06674.1 - 0.017 15.4 0.1 9.4 6.8 0.0 3.6 3 0 0 3 3 3 0 Clathrin propeller repeat WD40_3 PF15911.5 GAN06674.1 - 0.058 13.4 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat CPSF_A PF03178.15 GAN06674.1 - 0.062 12.6 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 CPSF A subunit region Stig1 PF04885.13 GAN06674.1 - 0.14 12.7 1.8 0.14 12.7 0.4 1.6 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Rhomboid PF01694.22 GAN06675.1 - 5.2e-05 23.3 6.5 8.3e-05 22.6 6.5 1.3 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.16 GAN06675.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 GAN06675.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain DER1 PF04511.15 GAN06675.1 - 0.0021 18.0 2.5 0.0027 17.6 2.5 1.3 1 0 0 1 1 1 1 Der1-like family YppG PF14179.6 GAN06676.1 - 0.12 13.1 4.4 0.31 11.8 4.4 1.6 1 0 0 1 1 1 0 YppG-like protein Takusan PF04822.13 GAN06678.1 - 0.0048 16.8 1.0 0.0061 16.4 1.0 1.1 1 0 0 1 1 1 1 Takusan DUF892 PF05974.12 GAN06678.1 - 0.0055 16.7 1.8 0.0064 16.5 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF892) THOC7 PF05615.13 GAN06678.1 - 0.012 15.9 3.7 0.015 15.5 3.7 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF948 PF06103.11 GAN06678.1 - 0.019 15.2 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fungal_TACC PF12709.7 GAN06678.1 - 0.023 15.1 3.0 0.029 14.8 3.0 1.2 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins PIEZO PF15917.5 GAN06678.1 - 0.039 13.5 0.7 0.043 13.3 0.7 1.1 1 0 0 1 1 1 0 Piezo DUF5320 PF17253.2 GAN06678.1 - 0.043 14.9 0.2 0.047 14.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5320) ZapB PF06005.12 GAN06678.1 - 0.046 14.2 5.6 0.062 13.8 5.6 1.2 1 0 0 1 1 1 0 Cell division protein ZapB GreA_GreB_N PF03449.15 GAN06678.1 - 0.064 13.4 2.4 0.064 13.4 2.4 1.5 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Spc24 PF08286.11 GAN06678.1 - 0.14 12.4 3.4 0.16 12.2 3.4 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.10 GAN06678.1 - 0.15 12.3 3.7 0.21 11.9 3.7 1.2 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DivIC PF04977.15 GAN06678.1 - 0.3 10.9 6.6 0.37 10.6 5.9 1.6 1 1 0 1 1 1 0 Septum formation initiator LCD1 PF09798.9 GAN06678.1 - 0.79 8.2 5.3 0.96 7.9 5.3 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein ATP-synt_G PF04718.15 GAN06679.1 - 7e-22 78.1 0.9 8.5e-22 77.9 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DEAD PF00270.29 GAN06680.1 - 3.2e-47 160.5 0.0 8.4e-47 159.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN06680.1 - 2e-31 108.6 0.0 7.7e-29 100.3 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SpoIIID PF12116.8 GAN06680.1 - 0.045 13.9 0.8 0.22 11.6 0.4 2.3 2 0 0 2 2 2 0 Stage III sporulation protein D Aminotran_1_2 PF00155.21 GAN06681.1 - 3.1e-39 135.2 0.0 3.6e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAN06681.1 - 7.1e-06 24.8 0.0 1.6e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GAN06681.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.20 GAN06681.1 - 0.045 12.5 0.2 0.12 11.1 0.2 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fer4_14 PF13394.6 GAN06681.1 - 0.19 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Cyclin_N PF00134.23 GAN06682.1 - 3.6e-12 46.1 0.1 5.8e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN06682.1 - 3.9e-10 40.3 0.1 4.5e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin OPT PF03169.15 GAN06683.1 - 3.8e-184 613.8 45.0 4.3e-184 613.6 45.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MIF4G PF02854.19 GAN06684.1 - 2.9e-61 206.8 12.6 3.2e-34 118.4 0.3 3.6 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 GAN06684.1 - 1.6e-38 132.5 13.5 1.6e-38 132.5 13.5 3.5 3 0 0 3 3 3 2 Up-frameshift suppressor 2 Ras PF00071.22 GAN06685.1 - 3.2e-60 202.4 0.1 3.9e-60 202.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN06685.1 - 2.9e-35 121.1 0.1 7e-35 119.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN06685.1 - 4.1e-13 49.2 0.1 4.8e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN06685.1 - 9.4e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN06685.1 - 2.6e-05 24.2 0.5 0.23 11.3 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 GAN06685.1 - 3.4e-05 23.3 0.0 4.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAN06685.1 - 0.0025 17.4 0.1 0.0075 15.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAN06685.1 - 0.0042 17.5 0.1 0.0079 16.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 GAN06685.1 - 0.019 14.3 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 GAN06685.1 - 0.043 13.0 0.1 0.078 12.1 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit La PF05383.17 GAN06686.1 - 1.4e-07 31.4 0.0 5.1e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAN06686.1 - 1.9e-07 30.8 0.0 6.8e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb5_N PF03871.14 GAN06686.1 - 0.079 13.5 3.0 3.2 8.4 0.0 3.1 1 1 2 3 3 3 0 RNA polymerase Rpb5, N-terminal domain DAO PF01266.24 GAN06687.1 - 7.8e-57 193.4 0.0 8.9e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAN06687.1 - 0.0073 15.6 0.2 1 8.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAN06687.1 - 0.018 14.3 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 GAN06687.1 - 0.046 14.0 0.1 0.092 13.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Mqo PF06039.15 GAN06687.1 - 0.059 11.9 0.0 0.14 10.7 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) ApbA PF02558.16 GAN06687.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 GAN06687.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDYXXLXY PF14345.6 GAN06687.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 GDYXXLXY protein Lycopene_cycl PF05834.12 GAN06687.1 - 0.17 10.9 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pkinase PF00069.25 GAN06688.1 - 2.4e-74 250.0 0.0 3e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06688.1 - 8.3e-32 110.5 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN06688.1 - 0.019 13.9 0.1 0.079 11.9 0.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Ish1 PF10281.9 GAN06688.1 - 0.069 13.5 0.2 0.38 11.1 0.1 2.3 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein YrbL-PhoP_reg PF10707.9 GAN06688.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 GAN06688.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FCH PF00611.23 GAN06689.1 - 9e-09 35.5 0.5 9e-09 35.5 0.5 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 GAN06689.1 - 0.048 13.3 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain DUF1831 PF08866.10 GAN06689.1 - 0.11 12.9 1.1 0.73 10.3 0.5 2.4 2 0 0 2 2 2 0 Putative amino acid metabolism SH3_1 PF00018.28 GAN06689.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 SH3 domain DUF4473 PF14747.6 GAN06689.1 - 0.21 12.2 3.7 0.66 10.6 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4473) DUF2852 PF11014.8 GAN06689.1 - 1.2 9.3 7.6 0.11 12.6 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SMC_N PF02463.19 GAN06690.1 - 4.5e-63 212.6 55.8 1e-33 116.7 8.7 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAN06690.1 - 6.8e-26 90.9 0.1 2.2e-25 89.2 0.1 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 GAN06690.1 - 1.6e-13 51.1 17.2 1.6e-13 51.1 17.2 4.3 2 2 2 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 GAN06690.1 - 7.7e-12 45.6 12.3 1.2e-06 28.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAN06690.1 - 3e-06 26.9 0.0 9.9e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Laminin_II PF06009.12 GAN06690.1 - 0.0016 18.5 10.5 0.0016 18.5 10.5 8.2 3 2 5 8 8 8 1 Laminin Domain II Prefoldin_2 PF01920.20 GAN06690.1 - 0.019 14.9 1.2 0.019 14.9 1.2 11.3 4 3 4 9 9 9 0 Prefoldin subunit ABC_tran PF00005.27 GAN06690.1 - 0.08 13.4 0.0 0.08 13.4 0.0 6.6 4 2 0 4 4 4 0 ABC transporter Ribosomal_L18A PF01775.17 GAN06691.1 - 1.3e-52 177.0 2.7 2e-52 176.4 2.7 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Dickkopf_N PF04706.12 GAN06691.1 - 0.18 12.3 8.9 0.3 11.6 1.2 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region PLA2_B PF01735.18 GAN06692.1 - 9.3e-38 129.9 3.2 5.4e-18 64.7 0.0 3.0 3 0 0 3 3 3 2 Lysophospholipase catalytic domain DUF3632 PF12311.8 GAN06692.1 - 0.013 15.9 0.2 0.091 13.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) GTP_CH_N PF12471.8 GAN06694.1 - 5.5e-92 306.8 0.0 8.3e-92 306.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 GAN06694.1 - 2.4e-09 37.0 0.0 3.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 GAN06694.1 - 0.019 14.6 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family UPRTase PF14681.6 GAN06695.1 - 5.1e-63 212.3 0.0 6.4e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAN06695.1 - 0.00017 21.2 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1687 PF07955.11 GAN06696.1 - 8.4e-05 23.0 0.0 0.00013 22.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 GAN06696.1 - 0.00041 20.3 0.0 0.00082 19.3 0.0 1.8 1 1 0 1 1 1 1 ArsC family MRP-L20 PF12824.7 GAN06697.1 - 4e-22 79.1 1.0 4.9e-22 78.8 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 GAN06697.1 - 0.044 14.4 0.6 0.11 13.2 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 GAN06697.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain Pkinase PF00069.25 GAN06698.1 - 5.2e-42 144.0 0.3 4.2e-20 72.2 0.2 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06698.1 - 2.7e-13 49.8 0.7 1.2e-07 31.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Wbp11 PF09429.10 GAN06698.1 - 0.0022 18.4 5.2 0.0022 18.4 5.2 2.8 3 0 0 3 3 3 1 WW domain binding protein 11 RIO1 PF01163.22 GAN06698.1 - 0.029 14.0 0.0 0.099 12.2 0.0 1.9 1 1 1 2 2 2 0 RIO1 family DUF3818 PF12825.7 GAN06699.1 - 9.5e-94 314.2 2.0 1.7e-93 313.4 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 GAN06699.1 - 1.2e-15 57.6 1.0 3e-15 56.4 1.0 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 GAN06699.1 - 3.7e-14 52.7 0.3 2.1e-13 50.2 0.1 2.2 2 0 0 2 2 2 1 PX domain HTH_23 PF13384.6 GAN06700.1 - 0.00018 21.2 0.0 0.00046 19.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Myb_DNA-bind_6 PF13921.6 GAN06700.1 - 0.00051 20.2 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 GAN06700.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_Tnp_ISL3 PF13542.6 GAN06700.1 - 0.12 11.8 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Myb_DNA-binding PF00249.31 GAN06700.1 - 0.14 12.4 0.6 0.63 10.3 0.4 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain CDC50 PF03381.15 GAN06701.1 - 6.9e-90 301.4 0.1 8.1e-90 301.1 0.1 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RGS PF00615.19 GAN06703.1 - 7.2e-18 65.0 4.2 1.5e-17 63.9 4.2 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 GAN06703.1 - 2.3e-07 30.7 0.3 3.9e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain DS PF01916.17 GAN06703.1 - 0.073 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Deoxyhypusine synthase AtuA PF07287.11 GAN06704.1 - 9.8e-109 363.3 0.0 1.3e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA RicinB_lectin_2 PF14200.6 GAN06705.1 - 0.0035 18.0 1.1 5 7.9 0.0 3.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN06705.1 - 0.014 15.7 0.0 0.22 11.8 0.0 2.2 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain SPX PF03105.19 GAN06706.1 - 1.5e-34 120.6 8.8 9.1e-22 78.5 6.5 2.7 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 GAN06706.1 - 3.3e-34 118.8 27.1 4.6e-34 118.3 27.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN06706.1 - 3.6e-28 98.6 55.2 6.5e-24 84.6 31.9 2.2 1 1 1 2 2 2 2 Citrate transporter TMEM132D_C PF15706.5 GAN06706.1 - 1.1 9.1 5.4 1.7 8.4 0.3 2.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Mod_r PF07200.13 GAN06706.1 - 2 8.5 7.6 11 6.1 0.4 2.9 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein F-box-like PF12937.7 GAN06707.1 - 3.4e-05 23.7 0.1 9.5e-05 22.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN06707.1 - 0.0046 16.8 0.1 0.0099 15.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 GAN06707.1 - 0.033 13.9 5.6 0.31 10.7 0.1 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1699) Recep_L_domain PF01030.24 GAN06708.1 - 1.8e-08 34.5 4.9 0.0073 16.4 0.4 4.8 1 1 2 4 4 4 3 Receptor L domain DUF3971 PF13116.6 GAN06708.1 - 0.043 13.4 2.6 0.81 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function GSHPx PF00255.19 GAN06710.1 - 7.5e-44 147.7 0.2 9.9e-44 147.4 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GAN06710.1 - 2.7e-06 27.3 0.1 6.1e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAN06710.1 - 0.00036 20.3 0.2 0.01 15.6 0.2 2.2 1 1 0 1 1 1 1 Redoxin Lipase_3 PF01764.25 GAN06711.1 - 5e-12 45.9 0.0 1.3e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) C2 PF00168.30 GAN06711.1 - 3.6e-07 30.4 0.0 8.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain Ribosomal_L35Ae PF01247.18 GAN06712.1 - 1.6e-42 143.5 0.9 1.8e-42 143.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAN06712.1 - 0.0014 18.8 0.1 0.28 11.4 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Bcr-Abl_Oligo PF09036.10 GAN06712.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Kinesin PF00225.23 GAN06714.1 - 4.5e-94 315.1 0.0 7.2e-94 314.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAN06714.1 - 2.6e-17 63.1 0.0 1.2e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding EAP30 PF04157.16 GAN06714.1 - 0.1 11.9 1.0 0.24 10.7 1.0 1.6 1 0 0 1 1 1 0 EAP30/Vps36 family TCO89 PF10452.9 GAN06715.1 - 7.2e-14 51.7 2.2 7.2e-14 51.7 2.2 2.5 2 1 0 2 2 2 2 TORC1 subunit TCO89 WD40 PF00400.32 GAN06716.1 - 9.8e-08 32.6 5.2 0.073 14.0 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAN06716.1 - 5.5e-06 25.6 0.1 0.0088 15.0 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GAN06716.1 - 0.0004 20.6 0.0 0.3 11.4 0.0 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3746 PF12562.8 GAN06716.1 - 0.021 14.8 0.4 0.049 13.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) Pectate_lyase22 PF14583.6 GAN06716.1 - 0.032 12.9 0.2 0.055 12.1 0.1 1.4 1 1 0 1 1 1 0 Oligogalacturonate lyase bZIP_1 PF00170.21 GAN06717.1 - 8.1e-06 25.9 2.2 8.1e-06 25.9 2.2 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAN06717.1 - 4.5e-05 23.5 5.5 4.5e-05 23.5 5.5 2.4 1 1 1 2 2 2 1 Basic region leucine zipper RteC PF09357.10 GAN06717.1 - 0.0021 17.8 0.6 0.0033 17.1 0.6 1.4 1 0 0 1 1 1 1 RteC protein ECSIT_C PF14784.6 GAN06717.1 - 0.0064 16.8 1.0 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein bZIP_Maf PF03131.17 GAN06717.1 - 0.021 15.4 5.7 0.021 15.4 5.7 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor UPF0242 PF06785.11 GAN06717.1 - 0.17 12.0 10.5 0.28 11.3 10.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc42p PF11544.8 GAN06717.1 - 0.96 9.5 8.5 0.19 11.7 4.1 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p Csm1_N PF18504.1 GAN06717.1 - 1 9.8 9.2 5.6 7.4 8.8 2.5 1 1 0 1 1 1 0 Csm1 N-terminal domain TFIIA PF03153.13 GAN06717.1 - 1.8 8.5 28.3 3.6 7.5 28.3 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 GAN06718.1 - 0.00064 18.6 0.6 0.00064 18.6 0.6 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 GAN06718.1 - 0.017 15.2 0.5 0.025 14.7 0.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FHIPEP PF00771.20 GAN06718.1 - 0.21 10.0 0.4 0.33 9.4 0.4 1.3 1 0 0 1 1 1 0 FHIPEP family SpoIIP PF07454.11 GAN06718.1 - 5 6.5 15.5 11 5.4 15.5 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DAG_kinase_N PF14513.6 GAN06719.1 - 7 6.8 13.7 0.61 10.3 2.2 2.5 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus Glyco_hydro_47 PF01532.20 GAN06720.1 - 9e-155 516.0 0.1 1.1e-154 515.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CwsA PF10814.8 GAN06720.1 - 0.23 11.6 0.0 0.42 10.8 0.0 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Trypan_PARP PF05887.11 GAN06721.1 - 0.009 16.0 22.5 0.078 13.0 22.5 2.0 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PCRF PF03462.18 GAN06722.1 - 6.9e-60 202.2 0.2 6.9e-60 202.2 0.2 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAN06722.1 - 1.3e-40 137.9 3.8 2.7e-40 136.9 3.8 1.5 1 0 0 1 1 1 1 RF-1 domain NUDIX PF00293.28 GAN06723.1 - 3e-15 56.4 0.0 7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 GAN06723.1 - 1.6e-08 34.8 0.1 1.6e-08 34.8 0.1 2.8 3 0 0 3 3 3 1 Dcp2, box A domain LCAT PF02450.15 GAN06724.1 - 2.8e-82 277.0 0.0 2e-81 274.2 0.0 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PurA PF04845.13 GAN06725.1 - 0.016 14.6 0.1 0.039 13.3 0.1 1.7 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein IL3 PF02059.15 GAN06725.1 - 0.018 15.1 3.2 6.8 6.8 0.0 3.3 2 0 0 2 2 2 0 Interleukin-3 DUF4752 PF15944.5 GAN06725.1 - 1.7 8.8 4.1 5.9 7.0 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) MatE PF01554.18 GAN06727.1 - 4.5e-58 195.4 26.9 3.5e-33 114.6 7.4 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAN06727.1 - 6.1e-08 32.8 13.4 6.1e-08 32.8 13.4 3.7 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 GAN06727.1 - 0.0015 18.7 0.4 0.0029 17.7 0.4 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus S4 PF01479.25 GAN06728.1 - 1.4e-15 56.7 0.0 2.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 GAN06728.1 - 0.023 14.5 0.0 0.063 13.1 0.0 1.6 2 0 0 2 2 2 0 S4 domain Ub-Mut7C PF14451.6 GAN06728.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin p450 PF00067.22 GAN06729.1 - 7.2e-72 242.6 0.0 1.1e-71 242.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.15 GAN06730.1 - 1.2e-275 915.2 2.6 1.7e-275 914.7 2.6 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN06730.1 - 8.2e-12 45.5 3.8 3.7e-11 43.3 3.8 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAN06730.1 - 1.5e-11 44.6 0.0 1.9e-10 41.0 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAN06730.1 - 0.0018 18.1 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN06730.1 - 0.0038 16.7 0.1 0.58 9.6 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 GAN06730.1 - 0.005 17.0 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_20 PF00982.21 GAN06731.1 - 3.1e-164 547.1 0.1 4.3e-164 546.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN06731.1 - 1.4e-72 243.6 0.0 1.8e-71 240.0 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase FAD-oxidase_C PF02913.19 GAN06732.1 - 2.9e-59 200.7 0.0 4.5e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAN06732.1 - 4.6e-37 126.8 0.5 8.2e-37 126.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Relaxase PF03432.14 GAN06732.1 - 0.076 12.6 0.1 16 5.0 0.0 3.4 4 0 0 4 4 4 0 Relaxase/Mobilisation nuclease domain Atg14 PF10186.9 GAN06733.1 - 0.07 12.2 11.9 0.13 11.4 11.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2671 PF10877.8 GAN06733.1 - 0.072 12.9 2.4 0.086 12.6 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2671) Mvb12 PF09452.10 GAN06733.1 - 1 9.8 7.1 2.6 8.5 1.0 2.8 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 LMBR1 PF04791.16 GAN06733.1 - 1.7 7.5 6.4 2.1 7.1 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 GAN06733.1 - 4.8 5.7 16.6 3.3 6.2 14.8 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 GAN06733.1 - 7.3 6.1 11.9 13 5.2 11.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 GAN06733.1 - 7.7 6.6 10.2 13 5.9 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CHD5 PF04420.14 GAN06734.1 - 2e-58 196.8 2.8 2.5e-58 196.4 2.8 1.1 1 0 0 1 1 1 1 CHD5-like protein CSN5_C PF18323.1 GAN06734.1 - 0.063 14.2 0.6 0.097 13.6 0.6 1.2 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain ColG_sub PF18496.1 GAN06734.1 - 0.074 13.2 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Adap_comp_sub PF00928.21 GAN06735.1 - 2.1e-25 89.6 0.0 3.8e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAN06735.1 - 8.4e-06 25.8 0.6 1.4e-05 25.0 0.6 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CDC37_N PF03234.14 GAN06735.1 - 0.00062 20.7 5.7 0.5 11.3 0.3 2.6 2 0 0 2 2 2 2 Cdc37 N terminal kinase binding DUF4337 PF14235.6 GAN06735.1 - 0.056 13.6 3.5 0.1 12.7 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sel1 PF08238.12 GAN06738.1 - 4.3e-19 68.5 25.2 7.6e-06 26.4 0.1 8.3 7 2 1 8 8 8 6 Sel1 repeat TPR_16 PF13432.6 GAN06738.1 - 0.005 17.5 4.3 0.095 13.4 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DDE_3 PF13358.6 GAN06739.1 - 1.1e-22 80.4 0.0 1.2e-16 60.8 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 GAN06739.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 GAN06739.1 - 0.0033 18.0 0.0 0.008 16.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 GAN06739.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NUDIX PF00293.28 GAN06740.1 - 2.9e-10 40.3 0.0 4.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N PF00107.26 GAN06741.1 - 1.4e-20 73.6 0.0 2.6e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAN06741.1 - 2.6e-17 62.7 0.0 5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 GAN06741.1 - 2.2e-08 35.2 0.0 7.6e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase La PF05383.17 GAN06742.1 - 3.8e-21 74.9 0.5 3.8e-21 74.9 0.5 1.9 2 0 0 2 2 2 1 La domain SRF-TF PF00319.18 GAN06743.1 - 1.1e-20 72.8 0.1 1.8e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FRG1 PF06229.12 GAN06744.1 - 1.2e-11 44.7 4.1 2.8e-11 43.5 0.1 2.7 2 1 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 GAN06744.1 - 0.00011 22.4 0.0 0.00035 20.8 0.0 1.8 1 1 0 1 1 1 1 Fascin domain TFIIA_gamma_C PF02751.14 GAN06744.1 - 0.0097 16.0 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Sec62 PF03839.16 GAN06744.1 - 3.6 7.0 8.9 0.84 9.1 0.4 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Questin_oxidase PF14027.6 GAN06745.1 - 2.1e-23 83.4 0.1 2.7e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like SWIRM PF04433.17 GAN06746.1 - 8e-12 45.3 0.2 6.7e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 GAN06746.1 - 3e-10 40.1 0.0 8.2e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 GAN06746.1 - 1.2e-08 34.6 7.9 2.3e-08 33.7 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 GAN06746.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3704 PF12488.8 GAN06746.1 - 3.1 7.5 6.0 25 4.6 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3704) polyprenyl_synt PF00348.17 GAN06747.1 - 1.2e-96 322.8 0.1 1.5e-96 322.4 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CLP_protease PF00574.23 GAN06747.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Clp protease OSCP PF00213.18 GAN06748.1 - 1.5e-43 148.9 4.8 1.8e-43 148.6 4.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TPR_12 PF13424.6 GAN06750.1 - 1.5e-12 47.6 14.7 1.8e-05 25.0 0.2 3.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN06750.1 - 5e-09 35.6 6.9 0.0016 18.4 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN06750.1 - 2e-08 33.7 3.7 2.7e-05 23.8 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN06750.1 - 1.1e-07 31.4 3.3 0.0013 18.7 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN06750.1 - 3.5e-06 27.6 3.8 0.068 13.8 0.1 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 GAN06750.1 - 9.4e-06 25.3 1.9 0.0042 16.5 0.3 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 GAN06750.1 - 1.2e-05 25.0 2.9 0.19 11.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN06750.1 - 4.3e-05 23.1 4.6 5.6e-05 22.7 0.3 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 GAN06750.1 - 0.00031 20.7 9.3 0.011 15.9 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN06750.1 - 0.00053 20.6 9.8 10 7.3 0.0 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAN06750.1 - 0.00068 19.4 6.8 0.00098 18.9 1.8 3.0 1 1 3 4 4 4 1 Tetratricopeptide repeat-like domain MIT PF04212.18 GAN06750.1 - 0.0018 18.3 6.5 0.079 13.0 0.6 4.2 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAN06750.1 - 0.0081 16.6 6.6 1.4 9.5 0.3 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAN06750.1 - 0.054 14.1 1.9 6.2 7.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAN06750.1 - 0.065 12.9 0.4 0.51 10.1 0.1 2.6 3 0 0 3 3 3 0 TPR repeat TPR_3 PF07720.12 GAN06750.1 - 0.49 10.5 3.4 1.5 8.9 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_2 PF13646.6 GAN06751.1 - 4.7e-07 30.1 3.9 0.012 16.0 0.0 5.6 6 1 0 6 6 6 1 HEAT repeats HEAT PF02985.22 GAN06751.1 - 4.2e-05 23.5 2.6 1.4 9.4 0.0 6.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 GAN06751.1 - 0.0021 18.5 0.4 0.67 10.5 0.0 4.7 6 0 0 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAN06751.1 - 0.019 15.5 3.4 11 6.7 0.0 5.3 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region DUF1902 PF08972.11 GAN06751.1 - 0.13 12.2 0.5 7.3 6.7 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) FANCI_S2 PF14676.6 GAN06751.1 - 0.94 9.8 4.8 2.9 8.2 0.4 3.3 3 1 0 3 3 3 0 FANCI solenoid 2 Trehalase PF01204.18 GAN06752.1 - 9.6e-175 582.3 1.6 1.2e-174 582.0 1.6 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 GAN06752.1 - 3.1e-12 46.0 0.2 6.2e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cyclin PF08613.11 GAN06753.1 - 1.8e-31 109.7 2.1 4.5e-31 108.4 2.1 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN06753.1 - 0.0012 18.6 0.1 0.0014 18.4 0.1 1.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain She9_MDM33 PF05546.11 GAN06754.1 - 0.068 13.0 2.2 0.16 11.8 1.4 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family Ntox21 PF15526.6 GAN06754.1 - 0.13 12.6 1.6 0.46 10.8 1.6 2.0 1 1 0 1 1 1 0 Novel toxin 21 MARVEL PF01284.23 GAN06755.1 - 3e-05 24.1 9.8 5.4e-05 23.3 9.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain Abhydrolase_9_N PF15420.6 GAN06755.1 - 0.023 14.7 1.5 0.023 14.7 1.5 1.7 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF3759 PF12585.8 GAN06756.1 - 2.1e-36 123.8 7.1 2.6e-36 123.5 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) AA_permease_2 PF13520.6 GAN06757.1 - 7.3e-63 212.9 43.7 9e-63 212.6 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN06757.1 - 3e-25 88.8 45.2 3.3e-24 85.3 45.2 1.9 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 GAN06758.1 - 3.9e-27 95.5 0.0 6.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN06758.1 - 1.8e-11 43.5 0.4 7.9e-11 41.4 0.4 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Catalase PF00199.19 GAN06759.1 - 2e-200 665.8 0.3 2.4e-200 665.5 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAN06759.1 - 1e-20 73.7 0.2 2.1e-20 72.7 0.2 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive WD40 PF00400.32 GAN06760.1 - 5.7e-42 140.9 26.0 1.6e-06 28.7 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06760.1 - 2.6e-10 40.4 1.9 0.55 10.6 0.0 5.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAN06760.1 - 4.8e-10 39.2 0.6 9.7e-10 38.2 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN06760.1 - 4.6e-08 32.7 0.4 9.6e-08 31.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 GAN06760.1 - 3.3e-06 26.0 7.3 0.3 9.7 0.1 5.6 4 2 2 6 6 6 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 GAN06760.1 - 5.1e-06 26.4 0.0 1.3e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 F-box PALB2_WD40 PF16756.5 GAN06760.1 - 0.001 18.1 0.9 4.7 6.0 0.0 3.9 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain PRANC PF09372.10 GAN06760.1 - 0.081 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 PRANC domain PQQ_3 PF13570.6 GAN06760.1 - 0.11 13.0 0.1 5.4 7.6 0.0 3.3 2 1 0 2 2 2 0 PQQ-like domain PQQ_2 PF13360.6 GAN06760.1 - 0.17 11.4 2.4 18 4.8 0.1 3.4 2 2 1 3 3 3 0 PQQ-like domain Pkinase PF00069.25 GAN06761.1 - 3.7e-44 151.1 0.0 2.3e-42 145.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06761.1 - 3.1e-24 85.7 0.0 6.2e-24 84.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN06761.1 - 0.00099 18.0 0.0 0.0012 17.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAN06761.1 - 0.0087 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAN06761.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAN06761.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 GAN06761.1 - 0.19 11.0 0.0 0.4 9.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like SDA1 PF05285.12 GAN06762.1 - 2.5e-05 23.9 30.8 2.8e-05 23.7 30.8 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAN06762.1 - 0.00069 18.0 35.1 0.00078 17.8 35.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GAN06762.1 - 0.0022 16.4 26.6 0.0031 15.9 26.6 1.3 1 0 0 1 1 1 1 CDC45-like protein SpoIIP PF07454.11 GAN06762.1 - 0.0092 15.5 8.4 0.012 15.0 8.4 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 GAN06762.1 - 0.047 13.1 26.2 0.067 12.6 26.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cas_VVA1548 PF09652.10 GAN06762.1 - 0.059 13.6 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) Mpp10 PF04006.12 GAN06762.1 - 0.13 10.7 31.2 0.16 10.4 31.2 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF2151 PF10221.9 GAN06762.1 - 0.18 10.4 6.8 0.2 10.2 6.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator BUD22 PF09073.10 GAN06762.1 - 0.25 10.7 32.5 0.3 10.4 32.5 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 GAN06762.1 - 1.7 7.4 15.4 1.9 7.2 15.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Serinc PF03348.15 GAN06762.1 - 2.8 6.8 8.1 14 4.5 8.1 1.9 1 1 0 1 1 1 0 Serine incorporator (Serinc) ERG4_ERG24 PF01222.17 GAN06763.1 - 3.7e-137 457.6 21.6 4.2e-137 457.4 21.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CitMHS PF03600.16 GAN06763.1 - 0.0029 16.9 5.5 0.73 9.0 0.0 2.8 3 0 0 3 3 3 2 Citrate transporter PEMT PF04191.13 GAN06763.1 - 0.035 14.5 0.1 0.035 14.5 0.1 3.2 3 0 0 3 3 3 0 Phospholipid methyltransferase R3H PF01424.22 GAN06764.1 - 0.031 14.3 0.3 0.091 12.8 0.0 2.0 2 0 0 2 2 2 0 R3H domain Pox_Ag35 PF03286.14 GAN06764.1 - 0.05 13.4 0.5 0.065 13.0 0.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3460 PF11943.8 GAN06764.1 - 0.057 13.7 0.6 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) R3H-assoc PF13902.6 GAN06764.1 - 0.084 13.3 4.7 0.16 12.4 2.9 2.2 2 1 0 2 2 2 0 R3H-associated N-terminal domain Abhydrolase_1 PF00561.20 GAN06765.1 - 5.2e-05 23.0 1.2 8.7e-05 22.3 0.3 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Exo84_C PF16528.5 GAN06766.1 - 1.8e-51 174.9 3.2 3.7e-51 173.9 3.2 1.5 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 GAN06766.1 - 8.5e-13 48.2 0.1 5.7e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 GAN06766.1 - 0.001 19.2 0.6 0.016 15.3 0.1 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 BSD PF03909.17 GAN06767.1 - 8.6e-18 64.1 1.5 2.2e-17 62.8 1.5 1.8 1 0 0 1 1 1 1 BSD domain DUF3524 PF12038.8 GAN06767.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) UCH PF00443.29 GAN06767.1 - 0.13 11.8 4.6 0.43 10.0 4.6 1.9 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AMMECR1 PF01871.17 GAN06768.1 - 7.9e-48 162.2 0.0 9e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 E1_dh PF00676.20 GAN06769.1 - 3.2e-97 325.1 0.1 4e-97 324.8 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAN06769.1 - 0.0076 15.5 0.1 0.041 13.1 0.0 2.1 3 0 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase BAR_3 PF16746.5 GAN06770.1 - 4e-54 183.8 7.1 4e-54 183.8 7.1 1.8 2 0 0 2 2 2 1 BAR domain of APPL family ArfGap PF01412.18 GAN06770.1 - 1.9e-37 127.9 1.8 3.3e-37 127.1 0.0 2.4 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 GAN06770.1 - 4.2e-19 68.9 7.5 2.2e-10 41.0 1.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 GAN06770.1 - 4.7e-14 52.8 0.1 1.3e-13 51.3 0.1 1.9 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 GAN06770.1 - 3.7e-13 49.7 0.2 2.1e-10 40.9 0.3 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN06770.1 - 1.6e-10 41.0 2.4 3.8e-06 27.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BAR PF03114.18 GAN06770.1 - 7.3e-10 38.9 5.7 7.3e-10 38.9 5.7 2.1 3 0 0 3 3 3 1 BAR domain Ank_3 PF13606.6 GAN06770.1 - 1.5e-08 34.2 0.1 0.00053 20.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAN06770.1 - 3.9e-08 33.4 0.0 0.0031 17.9 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Arfaptin PF06456.13 GAN06770.1 - 0.00074 19.2 5.0 0.0018 17.9 5.0 1.7 1 1 0 1 1 1 1 Arfaptin-like domain PH_13 PF16652.5 GAN06770.1 - 0.0033 17.2 0.1 0.0088 15.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Vps5 PF09325.10 GAN06770.1 - 0.0043 16.6 3.1 0.0099 15.4 3.1 1.6 1 0 0 1 1 1 1 Vps5 C terminal like zf-B_box PF00643.24 GAN06770.1 - 0.016 15.4 0.2 0.037 14.2 0.2 1.6 1 0 0 1 1 1 0 B-box zinc finger DivIVA PF05103.13 GAN06770.1 - 0.6 10.2 4.8 0.4 10.8 0.1 2.7 2 0 0 2 2 2 0 DivIVA protein DUF5327 PF17261.2 GAN06770.1 - 3.1 8.6 9.9 0.069 13.9 2.0 2.4 3 0 0 3 3 2 0 Family of unknown function (DUF5327) Zn_clus PF00172.18 GAN06771.1 - 5.7e-05 23.1 12.8 0.00013 22.0 12.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GGGtGRT PF14057.6 GAN06772.1 - 0.088 11.8 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 GGGtGRT protein ADH_N_assoc PF13823.6 GAN06772.1 - 0.096 12.6 0.8 0.18 11.8 0.8 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated LSM PF01423.22 GAN06773.1 - 1.4e-21 75.9 0.0 1.7e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAN06773.1 - 0.0045 17.1 0.0 0.005 17.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Nbas_N PF15492.6 GAN06773.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Reticulon PF02453.17 GAN06775.1 - 4.4e-20 72.2 4.3 6e-20 71.8 4.3 1.2 1 0 0 1 1 1 1 Reticulon DUF1993 PF09351.10 GAN06775.1 - 0.058 13.5 0.2 0.09 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Dicty_REP PF05086.12 GAN06776.1 - 0.029 12.4 4.7 0.034 12.1 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HLH PF00010.26 GAN06777.1 - 3e-14 52.7 1.8 6.8e-14 51.6 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.8 GAN06777.1 - 0.0024 18.2 0.3 0.084 13.2 0.0 2.5 2 0 0 2 2 2 1 Patatin phospholipase HEAT_2 PF13646.6 GAN06778.1 - 1.1e-09 38.5 0.4 0.019 15.4 0.0 5.4 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.22 GAN06778.1 - 5.4e-09 35.6 18.5 0.85 10.0 0.1 9.4 10 0 0 10 10 10 4 HEAT repeat Cohesin_HEAT PF12765.7 GAN06778.1 - 2.6e-05 24.4 1.4 22 5.4 0.1 5.6 4 1 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 GAN06778.1 - 0.0003 20.9 2.4 0.12 12.6 0.0 4.6 4 2 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 GAN06778.1 - 0.0027 17.8 20.6 0.091 12.8 0.6 6.7 5 1 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 GAN06778.1 - 0.0075 16.2 4.1 0.03 14.3 3.0 2.6 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central DUF4042 PF13251.6 GAN06778.1 - 0.018 14.8 16.5 0.57 9.9 0.7 6.4 5 1 1 7 7 7 0 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 GAN06778.1 - 0.079 13.5 3.6 11 6.6 0.2 5.5 5 1 0 5 5 5 0 HEAT-like repeat V-ATPase_H_N PF03224.14 GAN06778.1 - 0.9 8.8 16.0 0.039 13.3 1.0 3.4 2 1 0 2 2 2 0 V-ATPase subunit H Forkhead PF00250.18 GAN06779.1 - 2.7e-33 114.1 0.3 5.9e-33 113.0 0.3 1.6 1 0 0 1 1 1 1 Forkhead domain FlgT_M PF16539.5 GAN06779.1 - 0.026 14.6 0.2 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 Flagellar assembly protein T, middle domain 2OG-FeII_Oxy_3 PF13640.6 GAN06780.1 - 2.3e-12 47.6 0.1 4.1e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 GAN06780.1 - 0.002 17.3 0.0 0.0023 17.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.20 GAN06780.1 - 0.0059 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AGTRAP PF06396.11 GAN06781.1 - 4.9e-10 39.4 0.0 5.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF2011 PF09428.10 GAN06782.1 - 0.00016 21.9 0.7 0.0011 19.1 0.1 2.7 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) PK PF00224.21 GAN06784.1 - 4.7e-167 555.2 1.3 6e-167 554.9 1.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAN06784.1 - 1.8e-38 131.4 0.0 5.5e-38 129.8 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAN06784.1 - 0.00097 18.3 0.3 0.0026 17.0 0.2 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Cellulase PF00150.18 GAN06784.1 - 0.024 14.1 0.1 0.19 11.1 0.1 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) IMPDH PF00478.25 GAN06784.1 - 0.041 12.9 0.1 0.36 9.8 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain RWD PF05773.22 GAN06785.1 - 3.3e-15 56.4 6.3 3.8e-15 56.2 6.3 1.0 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 GAN06786.1 - 9.6e-09 35.6 8.5 9.6e-09 35.6 8.5 2.1 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 RCC1 PF00415.18 GAN06787.1 - 1.9e-23 82.8 2.3 7.6e-08 32.9 0.0 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAN06787.1 - 3e-13 49.2 6.4 4.5e-08 32.7 0.8 4.3 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF1962 PF09227.10 GAN06787.1 - 0.33 11.3 5.9 0.2 12.1 0.5 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1962) Mit_ribos_Mrp51 PF11709.8 GAN06788.1 - 5.1e-16 59.2 10.2 4.5e-10 39.7 6.5 4.0 1 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit FHA PF00498.26 GAN06789.1 - 1.3e-14 54.2 0.2 1.3e-14 54.2 0.2 1.8 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 GAN06789.1 - 9.6e-12 44.4 7.9 1.9e-11 43.5 7.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAN06789.1 - 4e-09 36.7 7.9 6.3e-09 36.0 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN06789.1 - 4.5e-05 23.2 9.7 7.8e-05 22.4 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN06789.1 - 0.00011 21.9 7.4 0.00021 21.1 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 GAN06789.1 - 0.00041 20.6 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 GAN06789.1 - 0.00047 20.1 6.6 0.00092 19.1 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAN06789.1 - 0.01 16.1 8.4 0.028 14.7 8.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 GAN06789.1 - 0.022 14.7 3.3 0.04 13.8 3.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 GAN06789.1 - 0.076 13.1 1.6 0.14 12.2 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAN06789.1 - 0.14 12.0 6.4 0.32 10.9 6.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAN06789.1 - 0.15 12.1 10.8 0.34 11.0 10.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FAM110_N PF14161.6 GAN06790.1 - 0.0025 18.0 0.4 0.0064 16.7 0.4 1.7 1 0 0 1 1 1 1 Centrosome-associated N terminus KAsynt_C_assoc PF16197.5 GAN06790.1 - 0.22 12.0 6.1 0.19 12.2 0.5 2.8 3 0 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension Tma16 PF11176.8 GAN06791.1 - 1.9e-42 144.6 6.2 2.3e-42 144.3 6.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Acyltransf_C PF16076.5 GAN06792.1 - 2.8e-17 62.6 0.6 1e-16 60.8 0.1 2.1 3 0 0 3 3 3 1 Acyltransferase C-terminus Acyltransferase PF01553.21 GAN06792.1 - 7.8e-17 61.2 0.1 1.1e-15 57.5 0.2 2.4 1 1 0 1 1 1 1 Acyltransferase Rtt106 PF08512.12 GAN06793.1 - 3.6e-26 91.4 0.2 2e-25 89.0 0.0 2.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_18 PF18469.1 GAN06793.1 - 0.0046 16.9 1.2 0.015 15.3 1.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain NAD_binding_7 PF13241.6 GAN06794.1 - 2.4e-16 60.1 0.2 4.1e-16 59.3 0.2 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 GAN06794.1 - 2.6e-11 43.0 0.0 5.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 GAN06794.1 - 0.00098 18.5 0.1 0.0019 17.6 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central BRE1 PF08647.11 GAN06795.1 - 7.2e-16 58.1 12.2 7.2e-16 58.1 12.2 7.4 7 3 1 8 8 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 GAN06795.1 - 6.9e-06 25.8 10.9 6.9e-06 25.8 10.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN06795.1 - 0.0023 17.9 12.2 0.0049 16.8 12.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain UPF0242 PF06785.11 GAN06795.1 - 0.0051 17.0 11.1 0.0051 17.0 11.1 5.4 4 2 1 5 5 4 1 Uncharacterised protein family (UPF0242) N-terminus Prok-RING_4 PF14447.6 GAN06795.1 - 0.0069 16.2 12.4 0.0069 16.2 12.4 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAN06795.1 - 0.0074 16.3 7.8 0.052 13.6 8.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAN06795.1 - 0.0095 15.8 12.1 0.023 14.6 12.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN06795.1 - 0.07 13.0 13.8 0.18 11.7 13.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAN06795.1 - 0.16 11.8 7.8 0.058 13.3 3.4 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 GAN06795.1 - 0.73 10.2 17.9 0.071 13.5 12.4 2.1 2 0 0 2 2 2 0 Ring finger domain Ntox28 PF15605.6 GAN06795.1 - 1.9 8.8 12.6 3.6 7.9 2.0 3.9 2 1 0 2 2 2 0 Bacterial toxin 28 zf-C3HC4_4 PF15227.6 GAN06795.1 - 5.2 7.3 8.9 15 5.9 8.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPT PF03151.16 GAN06796.1 - 2.7e-20 72.9 22.0 3.5e-20 72.5 22.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN06796.1 - 1.2e-07 31.9 34.0 0.0011 19.1 18.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAN06796.1 - 0.1 11.7 15.8 7.3 5.7 16.4 2.7 1 1 1 2 2 2 0 Nucleotide-sugar transporter Topoisom_bac PF01131.20 GAN06797.1 - 3.3e-108 362.4 0.0 4e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 GAN06797.1 - 4.2e-28 97.2 10.3 1.2e-15 57.4 3.0 2.6 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 GAN06797.1 - 3.6e-18 65.7 0.0 6.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain F-box PF00646.33 GAN06798.1 - 0.00056 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN06798.1 - 0.0016 18.3 2.2 0.0023 17.8 0.5 2.0 2 0 0 2 2 2 1 F-box-like Evr1_Alr PF04777.13 GAN06799.1 - 2.3e-22 79.3 0.1 3.3e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family ATG22 PF11700.8 GAN06800.1 - 4.9e-103 345.3 23.5 5.7e-103 345.1 23.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAN06800.1 - 3.6e-13 49.2 36.7 3e-10 39.6 21.2 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Rep_fac-A_C PF08646.10 GAN06801.1 - 3.9e-49 166.1 5.3 2.1e-48 163.8 1.0 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GAN06801.1 - 5.2e-33 112.9 1.2 1e-31 108.7 0.1 2.7 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 GAN06801.1 - 4.2e-21 74.9 1.3 9e-21 73.8 0.7 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GAN06801.1 - 1e-11 44.7 0.1 6.9e-09 35.6 0.0 3.3 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 GAN06801.1 - 4.5e-05 23.7 0.4 0.00026 21.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 GAN06801.1 - 6.2e-05 22.8 0.0 0.058 13.1 0.0 2.4 1 1 1 2 2 2 2 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 GAN06801.1 - 0.00041 20.3 0.3 0.0032 17.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) C1_1 PF00130.22 GAN06801.1 - 0.019 14.8 1.4 0.041 13.8 1.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 GAN06801.1 - 0.035 14.1 1.7 0.1 12.6 1.7 1.7 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 GAN06801.1 - 0.45 10.2 3.1 6.9 6.4 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Cys_Met_Meta_PP PF01053.20 GAN06802.1 - 3.8e-142 473.4 0.0 4.3e-142 473.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAN06802.1 - 2.2e-10 40.2 0.1 4e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAN06802.1 - 1.4e-08 34.1 0.4 2.1e-08 33.6 0.4 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAN06802.1 - 4.2e-05 23.0 0.1 7.5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 GAN06802.1 - 0.00023 19.8 0.0 0.00032 19.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 GAN06802.1 - 0.0076 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 GAN06802.1 - 0.079 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein zf-met PF12874.7 GAN06803.1 - 3.3e-11 43.2 66.1 0.034 14.6 0.4 9.6 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN06803.1 - 2.9e-08 33.9 81.7 0.12 13.2 3.7 9.7 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN06803.1 - 5.1e-05 23.4 3.2 0.0015 18.7 0.2 9.1 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAN06803.1 - 0.0076 16.7 82.4 0.23 12.0 1.1 9.5 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 GAN06803.1 - 0.62 9.8 43.9 0.36 10.5 0.7 7.5 8 0 0 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain Cementoin PF10511.9 GAN06804.1 - 0.034 14.4 3.1 2.8 8.4 0.8 2.6 2 0 0 2 2 2 0 Trappin protein transglutaminase binding domain Cob_adeno_trans PF01923.18 GAN06806.1 - 8.3e-46 156.1 0.0 3.9e-45 153.9 0.0 2.1 1 1 1 2 2 2 1 Cobalamin adenosyltransferase Na_sulph_symp PF00939.19 GAN06806.1 - 7.9e-27 94.4 36.8 1.2e-26 93.8 36.8 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN06806.1 - 1.5e-26 93.3 43.6 3.2e-17 62.7 16.2 2.3 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 GAN06806.1 - 8.3e-18 65.5 10.0 4.3e-14 53.2 0.2 3.0 2 1 1 3 3 3 2 SPX domain Mac PF12464.8 GAN06807.1 - 5.8e-14 52.1 0.5 1.2e-13 51.0 0.5 1.5 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.24 GAN06807.1 - 2e-13 49.5 16.5 9.9e-11 40.9 8.6 3.9 3 2 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAN06807.1 - 3.5e-10 39.4 12.9 1.6e-07 31.0 7.6 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Cep57_MT_bd PF06657.13 GAN06807.1 - 0.11 12.9 0.1 0.2 12.2 0.1 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 60KD_IMP PF02096.20 GAN06808.1 - 7.8e-17 61.7 4.2 1.6e-16 60.7 4.2 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein FMO-like PF00743.19 GAN06809.1 - 1.9e-15 56.3 0.4 1.3e-14 53.6 0.4 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAN06809.1 - 2.1e-10 40.3 4.7 3e-10 39.8 0.3 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAN06809.1 - 7.7e-07 28.7 0.0 4.2e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN06809.1 - 0.0019 18.4 0.0 0.0091 16.2 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN06809.1 - 0.0083 15.4 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN06809.1 - 0.2 11.6 1.0 28 4.7 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding EF-hand_1 PF00036.32 GAN06810.1 - 9.4e-33 109.3 13.8 3.9e-08 32.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN06810.1 - 2.2e-30 104.9 4.6 1.3e-14 54.4 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN06810.1 - 5.5e-28 94.5 9.3 1.1e-08 34.3 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAN06810.1 - 9.2e-24 83.1 10.0 1.2e-12 47.4 0.2 3.8 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAN06810.1 - 8e-20 69.4 17.7 9.8e-07 28.0 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 GAN06810.1 - 3.9e-09 36.4 4.9 0.00058 19.8 0.9 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN06810.1 - 1.8e-07 31.5 0.8 0.021 15.2 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAN06810.1 - 3e-07 30.6 0.0 0.023 15.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 GAN06810.1 - 0.00024 21.9 0.2 0.14 13.1 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 GAN06810.1 - 0.0059 16.6 0.3 8.6 6.3 0.1 3.3 2 2 1 3 3 3 1 Caleosin related protein TerB PF05099.13 GAN06810.1 - 0.0078 16.2 0.2 3.4 7.6 0.1 2.3 2 0 0 2 2 2 2 Tellurite resistance protein TerB DUF5580 PF17743.1 GAN06810.1 - 0.023 13.3 0.0 0.023 13.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF1707 PF08044.11 GAN06810.1 - 0.044 13.9 0.0 2.8 8.1 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) DUF2666 PF10869.8 GAN06810.1 - 0.078 13.2 0.1 7.6 6.7 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2666) Dockerin_1 PF00404.18 GAN06810.1 - 0.092 12.9 9.9 8.2 6.7 0.0 3.4 2 1 1 3 3 3 0 Dockerin type I domain DUF533 PF04391.12 GAN06810.1 - 0.13 11.8 1.4 5.2 6.6 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF533) EF-hand_1 PF00036.32 GAN06811.1 - 7.7e-38 125.2 17.9 4.1e-10 38.5 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN06811.1 - 1.8e-34 118.0 8.3 4e-18 65.6 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN06811.1 - 2.7e-28 95.4 12.7 3.1e-08 32.9 0.2 4.7 4 2 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAN06811.1 - 1.2e-26 92.3 15.3 4.5e-17 61.6 0.7 3.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAN06811.1 - 2.1e-24 83.9 18.4 4.7e-07 29.0 0.2 4.4 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAN06811.1 - 9.6e-12 45.1 0.3 2.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAN06811.1 - 2.8e-10 40.1 5.8 5.8e-05 23.0 0.5 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN06811.1 - 1.5e-09 38.2 2.6 0.00043 20.6 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 GAN06811.1 - 3.1e-07 31.2 0.4 0.00085 20.2 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 GAN06811.1 - 0.00085 19.5 12.2 0.09 13.0 3.1 3.2 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 GAN06811.1 - 0.0022 16.6 0.1 0.0024 16.5 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Caleosin PF05042.13 GAN06811.1 - 0.0041 17.1 2.1 6.4 6.7 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein UPF0154 PF03672.13 GAN06811.1 - 0.017 15.2 0.0 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 GAN06811.1 - 0.026 15.3 0.5 3.9 8.3 0.0 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF2666 PF10869.8 GAN06811.1 - 0.034 14.4 0.5 2.9 8.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF533 PF04391.12 GAN06811.1 - 0.058 13.0 3.0 2.7 7.5 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF533) RNA_pol_Rpb4 PF03874.16 GAN06811.1 - 0.4 11.0 3.0 2.6 8.4 3.0 2.1 1 1 0 1 1 1 0 RNA polymerase Rpb4 PY_rept_46 PF09689.10 GAN06811.1 - 0.53 10.9 6.9 0.56 10.8 0.5 2.7 2 1 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) O-antigen_lig PF13425.6 GAN06812.1 - 3.8 6.2 3.7 6.1 5.5 3.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein UCH PF00443.29 GAN06813.1 - 1.8e-42 145.6 0.1 3.4e-42 144.7 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN06813.1 - 4.4e-10 39.6 9.8 3.6e-09 36.7 9.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4385 PF14328.6 GAN06813.1 - 0.043 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) DUF4606 PF15379.6 GAN06813.1 - 0.22 11.8 3.5 0.58 10.4 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Zn_Tnp_IS1595 PF12760.7 GAN06813.1 - 0.59 10.2 5.2 14 5.7 1.4 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_L38e PF01781.18 GAN06814.1 - 1.4e-35 121.2 3.6 1.5e-35 121.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family CRF PF00473.17 GAN06814.1 - 0.0053 16.8 0.5 0.01 15.9 0.5 1.4 1 0 0 1 1 1 1 Corticotropin-releasing factor family TFIID_NTD2 PF04494.15 GAN06814.1 - 0.041 14.1 0.2 0.048 13.9 0.2 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain CLTH PF10607.9 GAN06815.1 - 9.4e-17 61.3 0.3 2e-16 60.2 0.3 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain AAA_14 PF13173.6 GAN06815.1 - 0.056 13.5 2.8 0.13 12.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain LisH PF08513.11 GAN06815.1 - 0.14 12.2 1.0 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 LisH DUF3784 PF12650.7 GAN06815.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) MFS_1 PF07690.16 GAN06816.1 - 8.9e-28 97.2 56.5 8.9e-28 97.2 56.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN06816.1 - 0.25 9.8 43.7 0.069 11.7 13.8 3.8 1 1 3 4 4 4 0 MFS/sugar transport protein Ribosomal_L31 PF01197.18 GAN06817.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Phage_capsid PF05065.13 GAN06817.1 - 0.061 12.6 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Phage capsid family Pet127 PF08634.10 GAN06818.1 - 1.2e-110 369.3 2.5 2.1e-110 368.5 2.5 1.4 1 0 0 1 1 1 1 Mitochondrial protein Pet127 zf-MYND PF01753.18 GAN06819.1 - 7.2e-06 26.0 10.1 7.2e-06 26.0 10.1 2.5 2 0 0 2 2 2 1 MYND finger SR-25 PF10500.9 GAN06819.1 - 0.086 12.4 2.1 0.13 11.9 2.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CRM1_C PF08767.11 GAN06820.1 - 5e-07 29.2 1.2 0.00047 19.4 0.4 2.9 2 0 0 2 2 2 2 CRM1 C terminal DUF3369 PF11849.8 GAN06820.1 - 0.23 11.6 2.3 16 5.6 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3369) Reprolysin_5 PF13688.6 GAN06821.1 - 1.5e-40 139.4 1.1 1.5e-40 139.4 1.1 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 GAN06821.1 - 1.6e-39 135.9 1.4 2.4e-39 135.2 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAN06821.1 - 1.2e-36 126.2 0.1 3.1e-36 125.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 GAN06821.1 - 8.5e-16 58.5 22.7 8.5e-16 58.5 22.7 4.0 3 1 0 3 3 1 1 Disintegrin Reprolysin_3 PF13582.6 GAN06821.1 - 1.2e-12 48.5 0.0 5.6e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Muted PF14942.6 GAN06821.1 - 8.6e-07 29.4 12.8 1.7e-06 28.4 12.8 1.4 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Pep_M12B_propep PF01562.19 GAN06821.1 - 5.3e-06 26.7 0.1 1.3e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 GAN06821.1 - 0.00025 21.5 10.0 0.00025 21.5 10.0 3.9 2 1 1 3 3 1 1 ADAM cysteine-rich domain Mitofilin PF09731.9 GAN06821.1 - 0.18 10.6 11.1 0.24 10.2 11.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2315 PF10231.9 GAN06821.1 - 3.1 7.9 7.6 2.1 8.4 5.4 1.9 1 1 1 2 2 2 0 Apoptogenic protein 1 FapA PF03961.13 GAN06821.1 - 5.5 5.5 8.4 8.9 4.8 8.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2207 PF09972.9 GAN06821.1 - 6.2 5.5 8.7 21 3.7 8.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CALCOCO1 PF07888.11 GAN06822.1 - 2.1e-05 23.6 14.2 2.1e-05 23.6 14.2 2.0 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 GAN06822.1 - 0.00071 19.6 9.5 0.065 13.3 1.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DUF3450 PF11932.8 GAN06822.1 - 0.00073 18.9 19.3 0.0072 15.7 11.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 GAN06822.1 - 0.0012 18.7 21.5 0.012 15.4 20.9 1.9 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Nmad5 PF18757.1 GAN06822.1 - 0.004 17.4 9.5 0.011 16.0 9.5 1.7 1 1 0 1 1 1 1 Nucleotide modification associated domain 5 Sec34 PF04136.15 GAN06822.1 - 0.008 16.1 12.4 0.012 15.5 5.2 2.3 1 1 1 2 2 2 1 Sec34-like family Yuri_gagarin PF15934.5 GAN06822.1 - 0.018 14.9 13.3 0.027 14.3 13.3 1.2 1 0 0 1 1 1 0 Yuri gagarin Methyltransf_15 PF09445.10 GAN06822.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FapA PF03961.13 GAN06822.1 - 0.025 13.2 15.9 0.0095 14.6 9.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 GAN06822.1 - 0.034 14.1 24.7 0.38 10.7 12.7 2.9 2 1 1 3 3 2 0 Prefoldin subunit Laminin_II PF06009.12 GAN06822.1 - 0.072 13.1 8.0 0.034 14.2 4.0 1.9 1 1 1 2 2 2 0 Laminin Domain II CENP-H PF05837.12 GAN06822.1 - 0.11 12.9 15.5 0.028 14.8 7.2 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 GAN06822.1 - 0.13 12.5 24.2 0.33 11.2 11.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 GAN06822.1 - 0.23 11.7 19.4 0.052 13.7 9.1 3.1 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II FmiP_Thoc5 PF09766.9 GAN06822.1 - 0.24 10.6 15.5 0.098 11.9 5.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 FTA4 PF13093.6 GAN06822.1 - 0.25 11.2 18.1 0.4 10.5 9.7 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4570 PF15134.6 GAN06822.1 - 0.27 11.2 13.3 0.66 10.0 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Atg14 PF10186.9 GAN06822.1 - 0.35 9.9 14.9 0.66 9.0 14.9 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 GAN06822.1 - 0.35 11.2 2.2 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 GAN06822.1 - 0.37 11.0 16.7 0.24 11.7 5.6 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.6 GAN06822.1 - 0.58 8.7 16.2 1.2 7.7 16.2 1.4 1 1 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.11 GAN06822.1 - 0.6 10.7 16.4 1.2 9.7 10.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 GAN06822.1 - 0.62 7.9 14.7 0.77 7.6 14.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ParB PF08775.10 GAN06822.1 - 0.91 10.0 9.4 0.72 10.3 0.5 2.8 1 1 2 3 3 3 0 ParB family Exonuc_VII_L PF02601.15 GAN06822.1 - 0.99 8.9 9.6 1.3 8.6 9.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dam1 PF08653.10 GAN06822.1 - 1.1 9.1 3.5 23 4.9 0.1 3.2 2 2 0 3 3 3 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 GAN06822.1 - 1.1 9.4 12.0 0.73 10.0 3.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 GAN06822.1 - 1.4 7.7 24.9 0.49 9.2 14.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 GAN06822.1 - 1.5 9.3 26.6 0.94 9.9 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 GAN06822.1 - 1.8 9.1 31.0 0.4 11.2 17.6 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region TraF_2 PF13729.6 GAN06822.1 - 1.8 7.9 7.0 1.5 8.2 0.4 2.2 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Jnk-SapK_ap_N PF09744.9 GAN06822.1 - 2.1 8.6 26.5 2.4 8.3 20.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 GAN06822.1 - 2.2 7.8 20.1 24 4.4 19.8 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3287 PF11690.8 GAN06822.1 - 2.4 7.9 9.1 14 5.4 1.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) NYD-SP28_assoc PF14775.6 GAN06822.1 - 2.7 8.2 11.0 0.19 11.8 3.7 2.6 2 2 1 3 3 2 0 Sperm tail C-terminal domain GAS PF13851.6 GAN06822.1 - 3 7.1 22.3 9.3 5.5 22.3 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 GAN06822.1 - 3 8.4 7.3 24 5.5 2.8 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GAN06822.1 - 3 7.1 14.6 6.3 6.0 14.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.8 GAN06822.1 - 3 7.2 28.2 0.37 10.2 18.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) zf-C4H2 PF10146.9 GAN06822.1 - 3.4 7.9 16.9 2.8 8.2 15.7 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein HIP1_clath_bdg PF16515.5 GAN06822.1 - 3.5 8.3 17.2 5 7.8 4.9 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF349 PF03993.12 GAN06822.1 - 4.2 7.7 20.5 3 8.2 8.0 2.4 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Occludin_ELL PF07303.13 GAN06822.1 - 4.2 8.2 16.6 9.4 7.0 5.2 2.6 1 1 1 2 2 2 0 Occludin homology domain DUF2408 PF10303.9 GAN06822.1 - 5 7.7 13.4 3.5 8.2 9.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF4140 PF13600.6 GAN06822.1 - 6.2 7.3 20.6 3.6 8.1 3.2 3.3 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2203 PF09969.9 GAN06822.1 - 6.4 7.5 15.3 4.3 8.1 2.0 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 GAN06822.1 - 6.8 6.8 27.9 86 3.1 27.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TssO PF17561.2 GAN06822.1 - 6.8 6.8 14.2 4.8e+02 0.8 13.9 2.5 1 1 0 1 1 1 0 Type VI secretion system, TssO Prominin PF05478.11 GAN06822.1 - 7.2 4.4 10.5 1.5 6.7 5.4 1.8 1 1 1 2 2 2 0 Prominin Helo_like_N PF17111.5 GAN06822.1 - 7.3 5.9 14.0 0.78 9.1 0.8 2.6 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins DUF812 PF05667.11 GAN06822.1 - 7.7 5.3 23.6 18 4.1 23.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Tho2 PF11262.8 GAN06822.1 - 9.6 5.3 20.2 0.69 9.1 6.3 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 tRNA-synt_1e PF01406.19 GAN06823.1 - 5.3e-136 452.9 1.3 1e-135 451.9 1.3 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAN06823.1 - 7.3e-10 38.1 0.7 1.5e-06 27.3 0.3 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAN06823.1 - 0.00028 19.3 0.0 0.0011 17.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 GAN06823.1 - 0.003 16.5 0.1 0.059 12.3 0.1 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 GAN06823.1 - 0.009 14.9 3.2 0.018 14.0 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain SCAN PF02023.17 GAN06823.1 - 0.044 13.6 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 0 SCAN domain DALR_2 PF09190.11 GAN06823.1 - 0.078 13.5 0.0 0.078 13.5 0.0 2.2 2 0 0 2 2 2 0 DALR domain Ribonuc_red_sm PF00268.21 GAN06824.1 - 4.2e-121 403.7 3.5 5.1e-121 403.4 3.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Glyco_transf_15 PF01793.16 GAN06826.1 - 8.4e-117 390.0 12.1 1.1e-116 389.7 12.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DAPDH_C PF16654.5 GAN06826.1 - 0.0017 18.2 0.2 0.003 17.4 0.2 1.3 1 0 0 1 1 1 1 Diaminopimelic acid dehydrogenase C-terminal domain PIF1 PF05970.14 GAN06828.1 - 1.6e-22 80.2 0.0 6.3e-18 65.1 0.1 2.0 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 GAN06829.1 - 1.8e-13 51.1 0.0 2.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF5069 PF16798.5 GAN06829.1 - 0.12 12.6 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) SPACA9 PF15120.6 GAN06831.1 - 0.0032 17.3 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 DUF3446 PF11928.8 GAN06832.1 - 0.0058 16.9 0.2 0.11 12.8 0.2 2.5 2 0 0 2 2 2 1 Early growth response N-terminal domain zf-HC5HC2H_2 PF13832.6 GAN06834.1 - 1.5e-31 108.8 9.3 1.5e-31 108.8 9.3 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAN06834.1 - 3.8e-25 88.0 7.3 3.8e-25 88.0 7.3 2.9 3 0 0 3 3 2 1 PHD-like zinc-binding domain EPL1 PF10513.9 GAN06834.1 - 2.8e-22 79.8 5.3 2.8e-22 79.8 5.3 4.4 3 2 0 3 3 2 1 Enhancer of polycomb-like Bromodomain PF00439.25 GAN06834.1 - 1.4e-21 76.3 3.6 1.5e-21 76.3 1.5 2.2 2 0 0 2 2 2 1 Bromodomain PHD_2 PF13831.6 GAN06834.1 - 1.5e-14 53.2 2.7 1.5e-14 53.2 2.7 2.7 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 GAN06834.1 - 1e-13 51.5 0.9 4.2e-13 49.5 0.1 2.5 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 GAN06834.1 - 1.8e-09 37.4 9.4 1.8e-09 37.4 9.4 2.9 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 GAN06834.1 - 0.011 15.3 2.3 0.011 15.3 2.3 2.8 3 0 0 3 3 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 GAN06834.1 - 0.016 15.1 1.6 0.016 15.1 1.6 2.5 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 GAN06834.1 - 0.89 9.6 4.0 4.2 7.6 4.0 2.2 1 0 0 1 1 1 0 AT hook motif C1_2 PF03107.16 GAN06834.1 - 4.8 7.6 17.2 5.5 7.4 3.6 2.8 2 0 0 2 2 2 0 C1 domain UDPGT PF00201.18 GAN06835.1 - 3e-28 98.9 0.0 4.2e-28 98.4 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN06835.1 - 9.6e-08 32.2 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Type_III_YscX PF09474.10 GAN06835.1 - 0.16 12.3 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) VTC PF09359.10 GAN06836.1 - 2.2e-66 224.1 0.3 2.2e-66 224.1 0.3 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 GAN06836.1 - 8.4e-16 58.9 17.3 4.1e-07 30.3 0.5 4.1 3 1 1 4 4 4 4 SPX domain DUF202 PF02656.15 GAN06836.1 - 1.6e-11 44.5 0.5 3e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF1664 PF07889.12 GAN06836.1 - 0.052 13.6 0.4 0.13 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RAI16-like PF10257.9 GAN06836.1 - 0.11 11.3 0.0 6.4 5.5 0.1 2.3 2 1 0 2 2 2 0 Retinoic acid induced 16-like protein Cdh1_DBD_1 PF18196.1 GAN06836.1 - 0.73 10.2 6.0 3.7 7.9 0.0 3.2 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 Cas_Cas6 PF01881.16 GAN06836.1 - 0.74 10.4 3.3 0.67 10.5 0.9 2.2 3 0 0 3 3 3 0 CRISPR associated protein Cas6 Peptidase_M20 PF01546.28 GAN06837.1 - 1.1e-30 106.9 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAN06837.1 - 2.4e-06 27.4 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAN06837.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Mito_carr PF00153.27 GAN06838.1 - 1.1e-74 246.5 2.3 8e-25 86.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN06838.1 - 0.0015 17.8 1.6 0.82 8.8 0.1 3.1 2 1 1 3 3 3 3 Gammaproteobacterial serine protease WD40 PF00400.32 GAN06839.1 - 1.6e-15 57.2 20.1 1.3e-07 32.1 0.6 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06839.1 - 3.9e-06 27.1 0.4 0.19 12.1 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN06839.1 - 0.00054 18.7 0.2 1.1 7.8 0.1 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Adeno_E3_CR1 PF02440.15 GAN06839.1 - 0.052 13.3 2.9 0.17 11.7 2.0 2.2 1 1 1 2 2 2 0 Adenovirus E3 region protein CR1 PQQ_3 PF13570.6 GAN06839.1 - 0.13 12.8 4.8 30 5.3 0.0 4.5 3 1 1 4 4 4 0 PQQ-like domain Cas1_AcylT PF07779.12 GAN06840.1 - 1.1e-130 436.8 31.6 1.5e-130 436.3 31.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 GAN06840.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF3687 PF12459.8 GAN06840.1 - 1.5 8.4 8.1 6.5 6.3 0.3 3.5 3 0 0 3 3 3 0 D-Ala-teichoic acid biosynthesis protein CsbD PF05532.12 GAN06841.1 - 2.7e-16 59.2 16.6 6.1e-12 45.3 3.0 2.0 1 1 1 2 2 2 2 CsbD-like ApoLp-III PF07464.11 GAN06841.1 - 0.0045 17.1 0.5 0.0045 17.1 0.5 1.9 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) UQ_con PF00179.26 GAN06842.1 - 1.6e-45 154.2 0.0 4.1e-45 152.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAN06842.1 - 0.0094 15.6 0.0 0.032 13.9 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic E2 family B Ras PF00071.22 GAN06843.1 - 2.9e-49 166.8 0.4 3.3e-49 166.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN06843.1 - 2.3e-16 60.1 0.0 3.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN06843.1 - 1.9e-10 40.4 0.0 2.2e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN06843.1 - 5e-07 29.5 0.2 1.4e-06 27.9 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN06843.1 - 2.3e-06 27.6 0.1 0.00046 20.1 0.0 2.3 1 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAN06843.1 - 5.9e-06 25.9 0.1 2.1e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 GAN06843.1 - 3.6e-05 23.8 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAN06843.1 - 0.0015 18.0 0.1 0.0022 17.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 GAN06843.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 GAN06843.1 - 0.019 14.0 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Glutaredoxin PF00462.24 GAN06843.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin MMR_HSR1_Xtn PF16897.5 GAN06843.1 - 0.071 13.1 0.1 0.24 11.4 0.0 1.6 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 GAN06843.1 - 0.15 12.4 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Acyl-CoA_dh_1 PF00441.24 GAN06845.1 - 1.7e-35 122.5 0.6 3.3e-35 121.5 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DSPc PF00782.20 GAN06845.1 - 9.4e-30 103.1 0.1 2e-29 102.1 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Acyl-CoA_dh_M PF02770.19 GAN06845.1 - 1.1e-20 73.6 0.0 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 GAN06845.1 - 6.3e-19 67.9 0.0 2e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 GAN06845.1 - 1.4e-14 54.8 0.1 5.4e-14 52.8 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Y_phosphatase PF00102.27 GAN06845.1 - 0.012 15.2 0.1 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Glycos_transf_1 PF00534.20 GAN06846.1 - 4.3e-15 55.7 0.0 7.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN06846.1 - 3.3e-11 43.8 0.0 7e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAN06846.1 - 5.5e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN06846.1 - 8.8e-06 25.8 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAN06846.1 - 1.2e-05 25.8 0.0 2.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Methyltransf_11 PF08241.12 GAN06847.1 - 2.2e-15 57.1 0.0 4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN06847.1 - 4.4e-15 56.2 0.0 1.3e-14 54.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN06847.1 - 5.2e-13 49.2 0.0 8.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN06847.1 - 5.5e-10 39.2 0.0 1.4e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN06847.1 - 4.9e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN06847.1 - 6.8e-05 23.5 0.1 0.00036 21.2 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN06847.1 - 9e-05 22.0 0.0 0.004 16.6 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 GAN06847.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 GAN06847.1 - 0.0023 18.0 0.0 0.0051 16.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAN06847.1 - 0.0037 16.6 0.0 0.0077 15.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 GAN06847.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 GAN06847.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAN06847.1 - 0.035 13.6 0.1 0.32 10.5 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase small domain G_path_suppress PF15991.5 GAN06848.1 - 0.013 15.7 23.1 0.013 15.7 23.1 2.4 1 1 1 2 2 2 0 G-protein pathway suppressor DUF2046 PF09755.9 GAN06848.1 - 0.026 13.8 4.7 0.038 13.2 4.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF1192 PF06698.11 GAN06848.1 - 0.031 14.3 0.1 0.072 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Complex1_LYR PF05347.15 GAN06849.1 - 3.2e-19 68.7 0.4 4.4e-19 68.3 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAN06849.1 - 1.2e-06 29.2 0.1 1.4e-06 28.9 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 GAN06849.1 - 0.0004 20.9 0.1 0.0005 20.6 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF5358 PF17311.2 GAN06849.1 - 0.036 14.1 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5358) VitD-bind_III PF09164.10 GAN06849.1 - 0.076 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Vitamin D binding protein, domain III MFS_1 PF07690.16 GAN06850.1 - 3.8e-50 170.8 26.5 2.1e-49 168.4 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN06850.1 - 1.9e-11 43.5 9.9 1.9e-11 43.5 9.9 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter DUF4191 PF13829.6 GAN06850.1 - 4 6.7 4.7 0.96 8.7 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) CTNNBL PF08216.11 GAN06851.1 - 5.8e-39 132.4 2.0 5.8e-39 132.4 2.0 2.8 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear LigA PF07746.11 GAN06851.1 - 0.071 13.3 0.4 7.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit LemA PF04011.12 GAN06851.1 - 0.2 11.5 2.4 0.19 11.6 0.3 2.0 2 0 0 2 2 2 0 LemA family cwf21 PF08312.12 GAN06852.1 - 3.1e-15 56.0 2.8 3.1e-15 56.0 2.8 2.6 2 1 0 2 2 2 1 cwf21 domain NUDIX PF00293.28 GAN06854.1 - 1.2e-14 54.5 0.2 2.5e-14 53.5 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain TFIIF_alpha PF05793.12 GAN06854.1 - 5.2e-05 22.0 24.7 7.2e-05 21.6 24.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GAN06854.1 - 0.18 10.1 15.1 0.23 9.7 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAN06854.1 - 0.32 9.5 7.6 0.41 9.1 7.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SLC12 PF03522.15 GAN06854.1 - 5.7 5.9 17.7 0.15 11.0 11.2 1.6 2 0 0 2 2 2 0 Solute carrier family 12 DnaJ PF00226.31 GAN06855.1 - 1.9e-24 85.5 1.2 4.6e-24 84.3 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 GAN06855.1 - 8.7e-10 38.7 28.7 1.1e-05 25.3 2.7 3.3 2 2 1 3 3 3 3 Transmembrane Fragile-X-F protein Ly49 PF08391.10 GAN06855.1 - 0.016 15.6 1.2 17 5.8 1.9 3.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF2207 PF09972.9 GAN06855.1 - 0.03 13.1 5.8 0.11 11.3 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SecE PF00584.20 GAN06855.1 - 0.32 10.9 7.8 0.85 9.6 0.0 2.7 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex VIT1 PF01988.19 GAN06855.1 - 0.82 9.5 2.6 10 5.9 0.0 2.8 2 1 0 2 2 2 0 VIT family PAP2 PF01569.21 GAN06856.1 - 6.6e-30 103.6 0.7 6.6e-30 103.6 0.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF5510 PF17629.2 GAN06856.1 - 0.078 12.9 2.1 0.13 12.2 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5510) DUF3093 PF11292.8 GAN06856.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DUF1700 PF08006.11 GAN06856.1 - 0.66 9.5 2.7 0.38 10.3 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Sacchrp_dh_NADP PF03435.18 GAN06857.1 - 6.7e-18 65.2 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAN06857.1 - 0.00019 21.4 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAN06857.1 - 0.0042 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 GAN06857.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 GAN06857.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN06857.1 - 0.16 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_M1 PF01433.20 GAN06858.1 - 4e-46 157.3 0.0 6.4e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAN06858.1 - 3e-39 133.6 0.2 5.3e-39 132.8 0.2 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAN06858.1 - 4.9e-24 85.5 0.5 1e-23 84.5 0.5 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aldo_ket_red PF00248.21 GAN06859.1 - 1e-43 149.7 0.0 1.2e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cyclase_polyket PF04673.12 GAN06859.1 - 0.052 13.8 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Polyketide synthesis cyclase Proteasome PF00227.26 GAN06860.1 - 8.3e-28 97.2 0.0 1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit MFS_1 PF07690.16 GAN06861.1 - 6.3e-27 94.4 54.8 9.1e-26 90.6 54.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Isochorismatase PF00857.20 GAN06862.1 - 2.7e-33 115.6 0.1 3.5e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family NYN PF01936.18 GAN06862.1 - 0.013 16.0 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 NYN domain PH PF00169.29 GAN06863.1 - 0.061 13.8 0.2 0.41 11.2 0.1 2.6 2 0 0 2 2 2 0 PH domain ABC_membrane PF00664.23 GAN06864.1 - 1.8e-115 385.3 19.7 4.3e-59 200.4 9.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN06864.1 - 6e-70 234.1 2.9 5.2e-35 121.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAN06864.1 - 5.6e-12 45.6 6.9 1.7e-05 24.4 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN06864.1 - 3.4e-08 33.8 0.8 0.0052 17.0 0.1 4.0 4 1 0 4 4 3 2 AAA domain ABC_ATPase PF09818.9 GAN06864.1 - 4.1e-08 32.5 1.1 0.00031 19.7 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GAN06864.1 - 6.5e-08 33.1 0.8 0.018 15.4 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAN06864.1 - 7.9e-07 29.1 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 GAN06864.1 - 2.2e-06 28.1 0.6 1.6 9.1 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAN06864.1 - 7.8e-06 25.7 0.8 0.24 11.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAN06864.1 - 1.4e-05 24.7 1.1 0.099 12.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GAN06864.1 - 3.2e-05 23.3 0.1 0.073 12.3 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin Rad17 PF03215.15 GAN06864.1 - 4.4e-05 23.5 0.0 0.055 13.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain G-alpha PF00503.20 GAN06864.1 - 5.1e-05 22.6 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 GAN06864.1 - 0.00024 20.7 0.0 0.82 9.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 GAN06864.1 - 0.00051 20.2 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 GAN06864.1 - 0.0006 20.0 4.2 1.6 9.0 0.4 4.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 GAN06864.1 - 0.0023 18.2 0.1 2.3 8.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 GAN06864.1 - 0.0028 17.4 0.2 1.4 8.7 0.0 3.1 3 0 0 3 3 3 1 Cytidylate kinase AAA_18 PF13238.6 GAN06864.1 - 0.0028 18.2 0.0 3.7 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN06864.1 - 0.0036 17.7 0.0 4.7 7.6 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_5 PF07728.14 GAN06864.1 - 0.0046 17.0 0.2 7.1 6.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 GAN06864.1 - 0.0048 16.5 0.1 0.92 9.1 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 GAN06864.1 - 0.0093 15.7 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAN06864.1 - 0.017 14.3 0.0 0.45 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 GAN06864.1 - 0.032 14.0 0.2 33 4.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 GAN06864.1 - 0.061 13.1 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2207 PF09972.9 GAN06864.1 - 0.071 11.9 0.0 0.071 11.9 0.0 4.5 4 1 0 4 4 4 0 Predicted membrane protein (DUF2207) IstB_IS21 PF01695.17 GAN06864.1 - 0.1 12.3 1.6 18 5.0 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 GAN06864.1 - 0.12 12.5 0.0 27 4.9 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 GAN06864.1 - 0.22 11.1 2.9 5.9 6.4 0.1 3.2 4 0 0 4 4 3 0 AAA domain Corona_nucleoca PF00937.18 GAN06864.1 - 0.28 10.2 2.4 0.45 9.5 2.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PrgI PF12666.7 GAN06864.1 - 0.4 11.4 0.1 0.4 11.4 0.1 4.8 7 0 0 7 7 3 0 PrgI family protein AAA_15 PF13175.6 GAN06864.1 - 0.49 10.0 6.4 0.46 10.1 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain Connexin PF00029.19 GAN06864.1 - 0.69 9.6 2.7 0.86 9.3 0.2 2.2 2 0 0 2 2 2 0 Connexin tRNA-synt_1 PF00133.22 GAN06865.1 - 7.3e-185 615.7 0.1 1.4e-183 611.5 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAN06865.1 - 8.8e-31 106.9 0.1 1.9e-30 105.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAN06865.1 - 1.5e-17 63.4 6.3 2.2e-08 33.2 0.1 5.1 4 2 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAN06865.1 - 2.1e-08 33.9 0.0 2.2e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAN06865.1 - 9.1e-06 25.2 0.5 0.11 11.8 0.0 2.9 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 GAN06865.1 - 0.035 13.4 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Val_tRNA-synt_C PF10458.9 GAN06865.1 - 0.11 12.8 2.1 0.26 11.6 2.1 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm APG17 PF04108.12 GAN06865.1 - 0.14 11.2 1.1 0.3 10.1 1.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 PTR2 PF00854.21 GAN06867.1 - 3.3e-85 286.3 10.4 5.5e-85 285.6 10.4 1.3 1 0 0 1 1 1 1 POT family DUF4212 PF13937.6 GAN06867.1 - 0.27 11.6 0.2 0.27 11.6 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) Mito_carr PF00153.27 GAN06868.1 - 2.3e-37 126.8 1.3 3.2e-19 68.6 0.2 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein PrcB_C PF14343.6 GAN06868.1 - 0.068 13.3 0.5 9.7 6.4 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal CENP-P PF13096.6 GAN06869.1 - 0.0011 18.7 0.4 0.0019 17.9 0.0 1.6 2 0 0 2 2 2 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUF4407 PF14362.6 GAN06869.1 - 4.3 6.6 13.4 7.9 5.7 13.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SF3A2 PF16835.5 GAN06870.1 - 8.8e-40 135.0 0.4 1.4e-39 134.3 0.4 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GAN06870.1 - 1.2e-07 31.9 1.7 1.2e-07 31.9 1.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 GAN06870.1 - 2.5e-05 24.2 0.7 4e-05 23.6 0.7 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 GAN06870.1 - 0.017 14.6 0.9 0.03 13.9 0.9 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ribosomal_S11 PF00411.19 GAN06871.1 - 1.5e-23 83.3 0.4 4.8e-23 81.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S11 E_Pc_C PF06752.12 GAN06871.1 - 0.00087 19.5 5.1 0.0011 19.1 5.1 1.1 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus Sod_Fe_C PF02777.18 GAN06872.1 - 1.4e-36 124.8 0.4 3.1e-36 123.6 0.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAN06872.1 - 1.1e-30 105.9 4.0 2.2e-30 104.9 4.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_S8 PF00082.22 GAN06873.1 - 4.3e-38 131.3 3.9 7.4e-38 130.5 3.9 1.3 1 0 0 1 1 1 1 Subtilase family zf-C2H2 PF00096.26 GAN06874.1 - 1.3e-09 38.0 27.1 5.4e-05 23.4 2.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN06874.1 - 6.7e-08 32.6 27.3 0.00016 21.9 5.9 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN06874.1 - 9.4e-07 29.2 25.1 0.03 15.2 3.7 4.1 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN06874.1 - 0.0021 18.3 5.8 0.31 11.4 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 GAN06874.1 - 0.38 10.6 27.4 0.18 11.6 0.6 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Ribosomal_L23 PF00276.20 GAN06875.1 - 3.1e-18 65.9 0.2 3.1e-18 65.9 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 TrbH PF07283.11 GAN06875.1 - 0.044 14.0 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Mito_carr PF00153.27 GAN06876.1 - 1.5e-65 217.2 3.8 7.3e-23 80.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CLTH PF10607.9 GAN06877.1 - 1.3e-31 109.4 2.3 2.8e-30 105.1 0.1 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 GAN06877.1 - 9.9e-10 38.3 0.4 2.6e-09 36.9 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAN06877.1 - 7.9e-07 28.9 0.9 1.8e-06 27.8 0.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAN06877.1 - 1.8e-05 25.0 1.4 4.8e-05 23.6 1.4 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAN06877.1 - 0.00021 21.1 1.2 0.00053 19.8 1.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAN06877.1 - 0.00023 21.3 1.4 0.00071 19.7 1.4 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAN06877.1 - 0.00042 20.1 1.3 0.00099 18.9 1.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN06877.1 - 0.0047 16.8 1.9 0.0047 16.8 1.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN06877.1 - 0.0051 16.6 2.1 0.017 14.9 2.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HPD PF05044.12 GAN06877.1 - 0.085 12.7 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Homeo-prospero domain UBA_e1_thiolCys PF10585.9 GAN06877.1 - 0.15 11.9 3.4 0.16 11.9 1.4 1.9 2 1 0 2 2 2 0 Ubiquitin-activating enzyme active site Fib_alpha PF08702.10 GAN06877.1 - 0.36 11.0 4.7 0.25 11.5 1.9 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-RING_4 PF14570.6 GAN06877.1 - 1.3 8.9 3.9 1.1 9.0 1.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2508 PF10704.9 GAN06877.1 - 2.4 8.4 6.3 1.5 9.1 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) UCH PF00443.29 GAN06878.1 - 6.2e-47 160.3 0.1 8.4e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAN06878.1 - 1.8e-12 46.8 0.2 7.8e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family UCH_1 PF13423.6 GAN06878.1 - 3.3e-09 36.8 13.0 3.8e-07 30.0 13.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TBK1_ULD PF18396.1 GAN06878.1 - 0.033 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF1168 PF06658.12 GAN06878.1 - 0.1 12.4 5.7 0.2 11.5 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) HECT PF00632.25 GAN06879.1 - 2.3e-96 322.9 0.0 4e-96 322.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 GAN06879.1 - 1.2e-92 310.8 1.9 1.2e-92 310.8 1.9 7.7 8 2 0 8 8 8 3 Domain of Unknown Function (DUF913) DUF908 PF06012.12 GAN06879.1 - 3.7e-66 224.0 5.3 6.5e-44 150.8 0.5 7.2 6 1 1 7 7 7 2 Domain of Unknown Function (DUF908) UBM PF14377.6 GAN06879.1 - 8.4e-19 66.4 8.9 2.8e-09 36.1 0.3 2.9 2 0 0 2 2 2 2 Ubiquitin binding region UBA PF00627.31 GAN06879.1 - 1.6e-10 40.7 0.4 4.8e-10 39.1 0.4 1.9 1 0 0 1 1 1 1 UBA/TS-N domain SET PF00856.28 GAN06880.1 - 2.4e-07 31.3 0.0 4.1e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 SET domain GCIP PF13324.6 GAN06882.1 - 1.1e-40 139.9 4.6 1.5e-40 139.4 4.6 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting RasGAP PF00616.19 GAN06882.1 - 0.0082 15.9 0.4 0.037 13.7 0.0 2.1 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase UPF0128 PF03673.13 GAN06882.1 - 0.052 13.0 0.1 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) ATPase PF06745.13 GAN06882.1 - 0.062 12.6 2.1 0.12 11.7 2.1 1.4 1 0 0 1 1 1 0 KaiC Acyltransf_C PF16076.5 GAN06882.1 - 0.29 11.3 2.2 0.74 9.9 0.1 2.6 3 1 0 3 3 3 0 Acyltransferase C-terminus DUF2408 PF10303.9 GAN06882.1 - 4.1 8.0 8.3 1.4 9.5 3.8 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) RhoGAP PF00620.27 GAN06883.1 - 3.6e-35 121.0 0.2 3.6e-35 121.0 0.2 2.4 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 GAN06883.1 - 0.012 15.8 11.3 0.071 13.3 4.7 3.1 2 0 0 2 2 2 0 LIM domain AAA PF00004.29 GAN06884.1 - 4.2e-06 27.2 0.2 9.3e-05 22.9 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAN06884.1 - 0.00055 19.9 0.2 5.5 6.9 0.0 3.3 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_22 PF13401.6 GAN06884.1 - 0.0013 19.0 0.0 0.0038 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN06884.1 - 0.0028 18.0 0.0 0.0093 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain V-SNARE PF05008.15 GAN06884.1 - 0.018 15.4 0.2 5 7.6 0.0 3.6 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SRP54 PF00448.22 GAN06884.1 - 0.027 14.1 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 GAN06884.1 - 0.065 13.1 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 GAN06884.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 GAN06884.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TsaE PF02367.17 GAN06884.1 - 0.1 12.6 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Homeodomain PF00046.29 GAN06885.1 - 5.6e-18 64.5 1.8 5.6e-18 64.5 1.8 1.9 2 0 0 2 2 2 1 Homeodomain UCH PF00443.29 GAN06886.1 - 5.7e-65 219.4 1.2 8.4e-65 218.8 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN06886.1 - 1e-23 84.5 0.1 1.4e-21 77.4 0.1 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 GAN06886.1 - 5.4e-11 42.7 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 GAN06886.1 - 4.7e-05 23.9 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 GAN06886.1 - 0.019 14.7 0.1 0.06 13.1 0.1 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zinc_ribbon_10 PF10058.9 GAN06886.1 - 0.078 12.7 0.5 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-4CXXC_R1 PF10497.9 GAN06886.1 - 0.17 12.1 0.8 0.39 11.0 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Peptidase_S9 PF00326.21 GAN06887.1 - 1.1e-57 194.9 1.3 2.1e-57 194.0 1.3 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 GAN06887.1 - 2.3e-08 33.1 0.0 3.1e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 GAN06887.1 - 6.4e-06 26.0 1.7 0.12 11.9 0.0 2.7 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAN06887.1 - 0.00027 20.7 4.9 0.038 13.6 2.3 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN06887.1 - 0.026 13.8 0.3 7.6 5.7 0.5 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN06887.1 - 0.12 13.0 5.7 0.13 12.9 4.1 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family SRF-TF PF00319.18 GAN06889.1 - 4e-24 83.8 0.0 6.3e-24 83.2 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AAA PF00004.29 GAN06890.1 - 7.2e-64 214.1 0.0 1.4e-43 148.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 GAN06890.1 - 2.8e-29 101.3 0.8 9.5e-29 99.6 0.8 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 GAN06890.1 - 1.4e-12 47.2 0.6 1e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAN06890.1 - 1.8e-12 48.0 4.9 2.1e-05 24.9 0.3 4.8 2 2 2 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 GAN06890.1 - 2.2e-08 34.7 0.0 0.0016 19.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAN06890.1 - 1.2e-06 28.6 0.0 0.017 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAN06890.1 - 2e-05 24.2 0.0 0.0043 16.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 GAN06890.1 - 3.3e-05 23.2 0.0 0.0025 17.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAN06890.1 - 6.4e-05 23.3 0.0 0.53 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 GAN06890.1 - 9e-05 22.5 0.0 0.53 10.3 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAN06890.1 - 0.00011 22.0 0.0 0.0029 17.4 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 GAN06890.1 - 0.00013 21.9 0.0 0.24 11.4 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 GAN06890.1 - 0.00022 21.0 0.0 0.6 9.8 0.0 2.8 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 GAN06890.1 - 0.0003 20.9 0.1 0.039 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 GAN06890.1 - 0.00041 20.1 0.0 0.087 12.5 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 GAN06890.1 - 0.00066 19.0 0.2 0.1 11.7 0.0 2.8 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_2 PF07724.14 GAN06890.1 - 0.00086 19.5 0.0 0.053 13.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAN06890.1 - 0.00088 19.6 6.0 1.2 9.4 0.1 4.9 4 2 1 6 6 5 1 AAA domain T2SSE PF00437.20 GAN06890.1 - 0.0013 17.9 0.1 0.0097 15.0 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.6 GAN06890.1 - 0.0015 18.9 0.0 0.35 11.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 GAN06890.1 - 0.0019 17.5 0.0 2.4 7.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 GAN06890.1 - 0.0041 17.1 2.9 4 7.3 0.5 3.9 3 1 0 3 3 3 1 NACHT domain ABC_tran PF00005.27 GAN06890.1 - 0.0067 16.9 0.1 7 7.2 0.0 3.8 4 0 0 4 4 3 0 ABC transporter AAA_24 PF13479.6 GAN06890.1 - 0.0076 16.0 0.1 2.6 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAN06890.1 - 0.008 16.4 0.0 6.6 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAN06890.1 - 0.0082 15.5 0.1 0.75 9.1 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 GAN06890.1 - 0.009 15.2 0.0 3.7 6.7 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 GAN06890.1 - 0.012 15.6 0.0 0.53 10.2 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 GAN06890.1 - 0.012 15.5 0.0 1.3 8.9 0.0 2.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAN06890.1 - 0.012 15.3 0.1 0.32 10.8 0.2 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAN06890.1 - 0.02 14.5 4.3 1.5 8.3 0.1 4.2 2 2 0 4 4 4 0 AAA domain AAA_3 PF07726.11 GAN06890.1 - 0.02 14.7 0.0 1.6 8.6 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAN06890.1 - 0.02 14.9 0.5 0.37 10.8 0.0 3.1 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.15 GAN06890.1 - 0.022 14.7 0.1 0.8 9.6 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 GAN06890.1 - 0.037 13.3 0.0 5.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PEX-2N PF09263.10 GAN06890.1 - 0.056 13.8 0.3 0.34 11.2 0.1 2.6 2 1 0 2 2 1 0 Peroxisome biogenesis factor 1, N-terminal cobW PF02492.19 GAN06890.1 - 0.068 12.8 0.6 1.8 8.1 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 GAN06890.1 - 0.084 13.2 1.0 2.4 8.5 0.1 3.0 3 0 0 3 3 2 0 AAA domain Cytidylate_kin2 PF13189.6 GAN06890.1 - 0.1 12.7 0.0 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family FAR1 PF03101.15 GAN06891.1 - 0.008 16.9 0.8 0.008 16.9 0.8 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain Spt20 PF12090.8 GAN06891.1 - 1.9 8.0 22.2 2.9 7.4 22.2 1.3 1 0 0 1 1 1 0 Spt20 family Calpain_III PF01067.22 GAN06891.1 - 3.8 7.8 10.0 3.6 7.8 6.1 2.3 2 1 0 2 2 2 0 Calpain large subunit, domain III FUSC PF04632.12 GAN06891.1 - 5.5 5.4 8.2 6.9 5.1 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Presenilin PF01080.17 GAN06891.1 - 6 5.5 6.8 7.1 5.3 6.8 1.2 1 0 0 1 1 1 0 Presenilin PepSY_TM_like_2 PF16357.5 GAN06891.1 - 6.5 6.7 6.0 11 6.0 6.0 1.4 1 0 0 1 1 1 0 Putative PepSY_TM-like eIF-5_eIF-2B PF01873.17 GAN06892.1 - 3.6e-41 139.7 0.2 6.1e-41 139.0 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 GAN06892.1 - 0.0011 18.4 0.4 0.0034 16.9 0.4 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding IF2_N PF04760.15 GAN06892.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.12 GAN06892.1 - 0.1 12.4 0.2 15 5.5 0.0 2.4 2 0 0 2 2 2 0 HypF finger Lar_restr_allev PF14354.6 GAN06892.1 - 0.11 12.9 1.0 0.49 10.8 0.9 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.10 GAN06892.1 - 9.4 6.7 8.2 7.7 7.0 0.3 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain Snapin_Pallidin PF14712.6 GAN06893.1 - 2.8e-09 37.3 3.3 6.2e-09 36.2 3.3 1.6 1 0 0 1 1 1 1 Snapin/Pallidin NPV_P10 PF05531.12 GAN06893.1 - 0.021 15.3 1.9 0.052 14.0 0.9 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Senescence_reg PF04520.13 GAN06893.1 - 9.4 7.1 7.9 25 5.7 0.3 2.2 1 1 1 2 2 2 0 Senescence regulator WD40 PF00400.32 GAN06894.1 - 1.7e-34 117.3 24.8 9.8e-07 29.4 0.1 7.3 8 0 0 8 8 6 6 WD domain, G-beta repeat F-box-like PF12937.7 GAN06894.1 - 2.3e-10 40.2 1.5 8.3e-10 38.4 0.4 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GAN06894.1 - 3.3e-10 40.1 11.8 0.022 15.2 0.0 7.6 6 2 4 10 10 9 4 Leucine Rich repeats (2 copies) ANAPC4_WD40 PF12894.7 GAN06894.1 - 1.3e-08 35.0 0.0 0.18 12.1 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN06894.1 - 2.4e-08 33.1 1.0 0.025 13.2 0.1 4.2 4 0 0 4 4 4 3 Nucleoporin Nup120/160 LRR_6 PF13516.6 GAN06894.1 - 0.0074 16.3 19.0 2.1 8.6 0.0 9.1 10 0 0 10 10 10 1 Leucine Rich repeat F-box PF00646.33 GAN06894.1 - 0.01 15.7 8.6 0.015 15.1 0.5 3.6 3 0 0 3 3 3 0 F-box domain DUF2464 PF10240.9 GAN06894.1 - 0.15 11.6 2.8 0.25 10.9 1.9 1.8 2 0 0 2 2 2 0 Multivesicular body subunit 12 YabA PF06156.13 GAN06894.1 - 0.15 12.7 0.7 0.46 11.1 0.7 1.8 1 0 0 1 1 1 0 Initiation control protein YabA UPF0449 PF15136.6 GAN06894.1 - 0.22 12.0 3.7 0.67 10.5 3.7 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Phage_tail_APC PF16778.5 GAN06894.1 - 0.95 9.4 4.9 3.7 7.5 0.1 3.2 3 0 0 3 3 3 0 Phage tail assembly chaperone protein AAA_23 PF13476.6 GAN06894.1 - 1.5 9.2 10.8 5.3 7.5 10.8 1.9 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 GAN06894.1 - 1.9 8.9 9.1 5.3 7.5 9.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2315 PF10231.9 GAN06895.1 - 2.9e-41 140.4 3.3 4.5e-41 139.8 3.3 1.3 1 0 0 1 1 1 1 Apoptogenic protein 1 Isochorismatase PF00857.20 GAN06896.1 - 6.9e-25 88.2 0.4 2.5e-24 86.4 0.4 1.9 1 1 0 1 1 1 1 Isochorismatase family Glyco_trans_4_2 PF13477.6 GAN06896.1 - 0.017 15.2 0.1 0.048 13.7 0.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like zf-ZPR1 PF03367.13 GAN06896.1 - 0.068 13.0 0.1 0.09 12.6 0.1 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain PP2C PF00481.21 GAN06897.1 - 3.6e-81 272.6 0.0 4.5e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Gti1_Pac2 PF09729.9 GAN06898.1 - 1.3e-43 149.1 4.6 1.4e-37 129.5 1.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family PEPCK_ATP PF01293.20 GAN06899.1 - 2.1e-225 748.7 0.0 2.5e-225 748.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 GAN06899.1 - 0.19 12.1 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 GAN06900.1 - 3.6e-24 84.6 6.3 0.00091 20.0 0.7 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06900.1 - 2.2e-06 27.9 0.0 0.54 10.6 0.0 4.8 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN06900.1 - 0.0087 15.1 0.0 0.11 11.5 0.0 2.4 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CelD_N PF02927.14 GAN06900.1 - 0.035 15.0 0.7 5.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Cellulase N-terminal ig-like domain GluRS_N PF18466.1 GAN06900.1 - 0.036 14.5 0.8 0.095 13.1 0.3 2.0 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain Nup160 PF11715.8 GAN06900.1 - 0.11 11.2 0.1 0.58 8.7 0.0 2.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Ubiquitin_4 PF18036.1 GAN06901.1 - 5.8e-20 71.1 0.3 1.9e-19 69.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 GAN06901.1 - 0.0016 18.2 0.1 6.9 6.5 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin family SAP18 PF06487.12 GAN06901.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) zf-C2H2 PF00096.26 GAN06902.1 - 8.3e-10 38.6 11.6 0.00018 21.7 3.5 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN06902.1 - 2.2e-07 31.1 7.5 0.0041 17.9 2.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN06902.1 - 4e-07 30.2 9.2 0.00029 21.1 0.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 GAN06902.1 - 0.014 15.8 0.7 0.014 15.8 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 GAN06902.1 - 0.04 14.2 12.6 1 9.7 7.7 3.1 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 GAN06902.1 - 0.048 13.7 5.7 0.051 13.6 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 GAN06902.1 - 0.1 13.3 1.9 1.6 9.4 0.3 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Clat_adaptor_s PF01217.20 GAN06903.1 - 1e-17 64.4 2.9 3.4e-17 62.7 2.9 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Phage_int_SAM_1 PF02899.17 GAN06904.1 - 0.022 15.1 0.3 0.056 13.7 0.3 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Oxidored-like PF09791.9 GAN06905.1 - 0.15 11.8 0.6 0.64 9.7 0.2 2.1 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal SdpA PF17418.2 GAN06905.1 - 0.16 11.8 1.8 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Sporulation delaying protein SdpA Steroid_dh PF02544.16 GAN06906.1 - 8.4e-19 68.0 2.7 2.5e-18 66.5 0.7 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 GAN06906.1 - 0.0051 17.2 1.1 0.017 15.5 0.5 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF5493 PF17597.2 GAN06906.1 - 0.01 16.1 0.5 0.01 16.1 0.5 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5493) Peptidase_S10 PF00450.22 GAN06907.1 - 3.8e-123 412.0 0.3 5e-123 411.6 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_pol_Rbc25 PF08292.12 GAN06908.1 - 8.5e-41 139.2 0.6 3.5e-38 130.8 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 GAN06908.1 - 9.9e-18 64.3 0.1 2.3e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF2722 PF10846.8 GAN06908.1 - 0.001 18.1 1.1 0.0016 17.5 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF2561 PF10812.8 GAN06908.1 - 0.0083 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Trep_Strep PF09605.10 GAN06908.1 - 0.013 15.5 0.6 0.013 15.5 0.6 2.3 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) S1 PF00575.23 GAN06908.1 - 0.055 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 S1 RNA binding domain DUF2371 PF10177.9 GAN06908.1 - 0.069 13.3 3.5 8.4 6.6 0.1 3.0 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Kinocilin PF15033.6 GAN06908.1 - 0.076 12.7 0.1 0.82 9.3 0.0 2.6 3 0 0 3 3 3 0 Kinocilin protein Peroxin-13_N PF04088.13 GAN06908.1 - 0.18 12.1 0.7 4.8 7.5 0.1 2.7 3 0 0 3 3 3 0 Peroxin 13, N-terminal region DUF3464 PF11947.8 GAN06908.1 - 0.27 11.0 1.1 1.1 8.9 0.2 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 HemY_N PF07219.13 GAN06908.1 - 0.62 10.3 0.1 0.62 10.3 0.1 2.1 2 0 0 2 2 1 0 HemY protein N-terminus DUF3742 PF12553.8 GAN06908.1 - 0.88 9.7 2.8 3 8.0 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) SseC PF04888.12 GAN06908.1 - 1.3 8.6 6.3 3 7.4 6.3 1.6 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Spt20 PF12090.8 GAN06908.1 - 1.4 8.5 15.6 2.8 7.5 15.6 1.4 1 0 0 1 1 1 0 Spt20 family CYSTM PF12734.7 GAN06908.1 - 2 8.8 7.3 5.9 7.3 7.3 1.8 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance ANAPC15 PF15243.6 GAN06908.1 - 3.2 8.2 8.1 1.6 9.2 0.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 UBA PF00627.31 GAN06909.1 - 3.4e-05 23.7 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_2 PF08587.11 GAN06909.1 - 0.14 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Pkinase PF00069.25 GAN06910.1 - 4.5e-23 82.0 0.8 4.9e-17 62.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06910.1 - 1.7e-12 47.2 0.2 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN06910.1 - 2.5e-09 36.4 0.1 3.3e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAN06910.1 - 0.0047 16.9 0.3 0.009 16.0 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 GAN06910.1 - 0.026 14.7 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 GAN06910.1 - 0.045 13.1 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FumaraseC_C PF10415.9 GAN06910.1 - 0.057 13.9 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Fumarase C C-terminus SET PF00856.28 GAN06911.1 - 2.7e-11 44.2 0.1 1.9e-09 38.2 0.1 2.2 1 1 0 1 1 1 1 SET domain DEAD PF00270.29 GAN06912.1 - 5.5e-47 159.8 0.0 1.5e-46 158.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN06912.1 - 2.1e-25 89.2 0.0 3e-24 85.5 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAN06912.1 - 8.2e-19 67.6 1.2 1.2e-18 67.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAN06912.1 - 3.4e-08 33.7 0.0 3.4e-08 33.7 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 GAN06913.1 - 7.1e-64 211.8 0.2 6.3e-23 80.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M3_N PF08439.10 GAN06913.1 - 0.053 13.8 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 Oligopeptidase F PMI_typeI PF01238.21 GAN06914.1 - 1.3e-121 406.3 0.0 1.6e-121 406.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 GAN06914.1 - 0.004 16.9 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain DUF295 PF03478.18 GAN06914.1 - 0.14 11.7 0.0 15 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF295) GATA PF00320.27 GAN06915.1 - 7.1e-15 54.3 7.2 1.3e-14 53.5 7.2 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 GAN06915.1 - 3.3e-14 52.9 0.0 6.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GAN06915.1 - 2.9e-08 33.7 0.0 6.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAN06915.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAN06915.1 - 4e-05 23.8 0.0 8.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 GAN06915.1 - 0.00048 20.2 0.0 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 GAN06915.1 - 0.012 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF4499 PF14934.6 GAN06916.1 - 6.1e-16 58.5 0.5 1.5e-15 57.3 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 GAN06916.1 - 3.1e-10 40.5 0.0 4.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Ribosomal_L38e PF01781.18 GAN06917.1 - 1.2e-31 108.6 1.2 2.6e-31 107.5 1.2 1.5 1 0 0 1 1 1 1 Ribosomal L38e protein family zf-C2H2_4 PF13894.6 GAN06918.1 - 0.002 18.8 2.2 0.017 15.9 1.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN06918.1 - 0.11 12.9 4.8 0.73 10.4 1.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pyr_redox_2 PF07992.14 GAN06919.1 - 1.1e-26 93.8 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN06919.1 - 4.7e-06 26.1 0.0 3.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN06919.1 - 8e-06 26.3 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAN06919.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN06919.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain THF_DHG_CYH_C PF02882.19 GAN06919.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 GAN06919.1 - 0.19 10.7 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 GAN06920.1 - 1.3e-20 73.6 45.3 1.1e-13 50.9 7.0 3.1 3 1 0 3 3 3 2 Major Facilitator Superfamily Cation_efflux PF01545.21 GAN06921.1 - 2e-49 168.1 8.4 2.5e-49 167.7 8.4 1.1 1 0 0 1 1 1 1 Cation efflux family Sterol-sensing PF12349.8 GAN06922.1 - 6.9e-24 84.4 4.1 1.7e-23 83.1 4.1 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAN06922.1 - 1.9e-10 39.6 3.7 2.6e-10 39.1 3.7 1.2 1 0 0 1 1 1 1 Patched family Nup160 PF11715.8 GAN06922.1 - 1.1e-05 24.3 1.8 0.003 16.3 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40 PF00400.32 GAN06922.1 - 0.0013 19.5 7.9 14 6.8 0.0 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Arrestin_N PF00339.29 GAN06923.1 - 3.6e-17 62.8 0.0 8.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN06923.1 - 6.3e-17 62.3 0.1 7.4e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 GAN06923.1 - 0.0034 17.1 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like DUF4293 PF14126.6 GAN06924.1 - 0.063 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) WD40 PF00400.32 GAN06925.1 - 5.9e-20 71.2 12.1 0.00019 22.1 0.2 6.2 6 2 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN06925.1 - 1.5e-11 44.5 0.0 0.0073 16.6 0.0 5.3 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN06925.1 - 5.9e-08 32.4 0.0 3.4e-07 29.9 0.0 1.9 1 1 1 2 2 2 1 WD40-like domain eIF2A PF08662.11 GAN06925.1 - 1.6e-06 28.1 0.1 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.25 GAN06926.1 - 8.9e-46 156.4 0.0 3.9e-45 154.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06926.1 - 5.2e-22 78.4 0.0 8.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN06926.1 - 0.0012 18.3 0.2 0.0055 16.0 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 GAN06926.1 - 0.0028 17.3 0.0 0.012 15.2 0.0 2.0 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Peptidase_S28 PF05577.12 GAN06926.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 UQ_con PF00179.26 GAN06927.1 - 1.8e-16 60.0 0.3 3.2e-16 59.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CLASP_N PF12348.8 GAN06928.1 - 2.9e-38 131.7 0.1 4.6e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 GAN06928.1 - 0.00045 20.3 0.0 6.4 7.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Npa1 PF11707.8 GAN06928.1 - 0.0018 17.7 0.4 1.2 8.4 0.0 2.3 1 1 0 2 2 2 2 Ribosome 60S biogenesis N-terminal Utp12 PF04003.12 GAN06928.1 - 0.024 15.0 0.0 0.093 13.0 0.0 2.0 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF1929 PF09118.11 GAN06928.1 - 0.042 14.1 0.1 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) TCTP PF00838.17 GAN06929.1 - 4e-77 258.2 0.9 4.5e-77 258.1 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.9 GAN06929.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 1 0 1 1 1 0 Spore germination protein GerPC EMP70 PF02990.16 GAN06930.1 - 1.1e-206 687.6 4.4 1.4e-206 687.2 4.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Methyltransf_25 PF13649.6 GAN06931.1 - 2.2e-12 47.5 0.0 8.2e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN06931.1 - 2.9e-12 47.1 0.0 8.8e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN06931.1 - 3.4e-11 43.3 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN06931.1 - 8.3e-08 32.2 0.0 3.7e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN06931.1 - 6.9e-07 28.8 0.0 2.5e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAN06931.1 - 2.7e-05 23.6 0.0 0.00012 21.4 0.0 1.9 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_12 PF08242.12 GAN06931.1 - 3.3e-05 24.5 0.0 0.0003 21.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAN06931.1 - 0.00031 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 GAN06931.1 - 0.0055 16.6 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 GAN06931.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 GAN06931.1 - 0.018 14.5 0.0 0.05 13.1 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.15 GAN06931.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_29 PF03141.16 GAN06931.1 - 0.047 12.2 0.0 0.45 9.0 0.0 2.0 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_45 PF02015.16 GAN06931.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 MTS PF05175.14 GAN06931.1 - 0.15 11.6 0.1 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain RFX_DNA_binding PF02257.15 GAN06932.1 - 2.5e-32 111.3 0.7 6.7e-32 110.0 0.7 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 GAN06932.1 - 0.00037 20.9 0.1 0.00098 19.6 0.1 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like DUF1314 PF07013.11 GAN06932.1 - 0.3 11.0 1.9 0.77 9.6 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) FAM199X PF15814.5 GAN06932.1 - 0.65 9.0 3.8 1.4 7.9 3.8 1.5 1 0 0 1 1 1 0 Protein family FAM199X Peptidase_M18 PF02127.15 GAN06933.1 - 9.6e-175 581.5 0.0 1.2e-174 581.2 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAN06933.1 - 3.4e-06 26.3 0.1 5.6e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase CRT10 PF08728.10 GAN06934.1 - 3.8e-12 45.2 3.2 1.6e-10 39.8 3.2 2.9 1 1 0 1 1 1 1 CRT10 ANAPC4_WD40 PF12894.7 GAN06934.1 - 9.5e-05 22.6 0.4 0.13 12.6 0.0 3.3 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN06934.1 - 0.00029 21.6 0.0 0.0013 19.5 0.0 2.2 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.8 GAN06934.1 - 0.0075 15.0 0.0 0.019 13.7 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Malate_synthase PF01274.22 GAN06936.1 - 2.7e-226 751.9 0.1 3.5e-226 751.6 0.1 1.1 1 0 0 1 1 1 1 Malate synthase Glyco_transf_49 PF13896.6 GAN06936.1 - 1.5e-59 202.1 3.1 3.2e-45 154.9 0.5 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 GAN06936.1 - 0.037 14.6 1.0 0.15 12.6 1.0 2.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF667 PF05018.13 GAN06937.1 - 1.8e-63 213.6 0.0 2.2e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) NDK PF00334.19 GAN06938.1 - 1.7e-38 131.6 0.0 2e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pkinase PF00069.25 GAN06939.1 - 3.6e-61 206.8 0.0 5.2e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06939.1 - 3.9e-35 121.4 0.0 5.4e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN06939.1 - 5.2e-07 29.3 0.0 7.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN06939.1 - 6e-06 25.3 0.2 1e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAN06939.1 - 0.032 13.2 0.5 0.054 12.4 0.5 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAN06939.1 - 0.066 12.6 0.3 0.13 11.6 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN06939.1 - 0.069 13.1 0.7 0.11 12.5 0.7 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family P34-Arc PF04045.14 GAN06940.1 - 2e-107 358.4 1.2 2.6e-107 358.0 1.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Vps4_C PF09336.10 GAN06940.1 - 0.083 12.9 0.2 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ARPC4 PF05856.12 GAN06940.1 - 0.13 11.8 2.7 0.94 9.1 2.6 2.2 1 1 1 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Acyltransferase PF01553.21 GAN06941.1 - 3.9e-37 126.9 0.1 5.6e-37 126.4 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase RGS PF00615.19 GAN06942.1 - 2.2e-05 24.7 0.0 9.7e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF3112 PF11309.8 GAN06942.1 - 0.096 12.1 3.1 1.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) PC-Esterase PF13839.6 GAN06943.1 - 3.3e-09 36.9 0.2 2e-06 27.8 0.0 3.0 3 1 0 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p ELO PF01151.18 GAN06944.1 - 3.3e-52 177.5 27.6 7.8e-52 176.3 28.0 1.4 2 0 0 2 2 2 1 GNS1/SUR4 family EF-hand_6 PF13405.6 GAN06944.1 - 2.3e-06 27.1 0.5 7.3e-06 25.5 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAN06944.1 - 6.7e-06 26.5 4.0 6.5e-05 23.3 3.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAN06944.1 - 0.0002 20.7 0.1 0.00067 19.0 0.1 2.0 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.9 GAN06944.1 - 0.028 14.7 0.9 0.075 13.4 0.9 1.8 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 GAN06944.1 - 0.054 13.3 2.8 0.087 12.7 0.3 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 GAN06944.1 - 0.077 12.5 1.5 0.088 12.3 0.0 1.9 2 0 0 2 2 2 0 EF hand RhoGAP PF00620.27 GAN06945.1 - 2.9e-34 118.1 0.0 4.8e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MFS_1_like PF12832.7 GAN06946.1 - 7.1e-52 176.5 18.5 1.1e-51 175.9 18.5 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAN06946.1 - 7.9e-15 54.6 29.7 2.4e-14 53.0 29.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 GAN06946.1 - 1.1e-08 34.3 11.1 2.1e-08 33.4 11.1 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 GAN06946.1 - 5.2e-05 22.4 5.8 5.2e-05 22.4 5.8 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter Kelch_4 PF13418.6 GAN06947.1 - 8e-28 96.2 12.9 2.1e-06 27.6 0.1 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN06947.1 - 2.6e-27 94.2 14.2 9.5e-09 35.2 0.4 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GAN06947.1 - 6.4e-26 89.7 7.5 1.7e-07 30.7 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAN06947.1 - 6.1e-24 83.6 11.4 4.1e-07 29.8 0.3 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 GAN06947.1 - 2.2e-23 82.0 4.8 2.1e-05 24.7 0.0 7.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN06947.1 - 4.6e-22 77.1 8.6 1.8e-07 30.9 0.1 6.6 6 0 0 6 6 6 5 Kelch motif YojJ PF10372.9 GAN06947.1 - 0.058 13.5 0.4 0.21 11.7 0.4 1.9 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus ACP_PD PF04336.12 GAN06947.1 - 0.087 13.3 4.4 0.17 12.3 1.9 2.4 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase MSC PF09402.10 GAN06948.1 - 2.4e-46 158.7 0.0 4.5e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 GAN06948.1 - 0.0029 17.3 0.0 0.013 15.2 0.0 2.3 1 0 0 1 1 1 1 HeH/LEM domain O-ag_pol_Wzy PF14296.6 GAN06948.1 - 0.0081 14.9 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy SPESP1 PF15754.5 GAN06948.1 - 0.065 12.4 2.8 0.11 11.7 2.8 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Phage_int_SAM_5 PF13102.6 GAN06948.1 - 0.12 12.7 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF4203 PF13886.6 GAN06949.1 - 1.2e-38 132.8 39.4 1.5e-38 132.5 39.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Ribosomal_L24e PF01246.20 GAN06950.1 - 4.7e-31 106.8 7.5 4.7e-31 106.8 7.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e RasGEF PF00617.19 GAN06951.1 - 4.1e-36 124.8 4.6 1.4e-35 123.1 4.6 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN06951.1 - 1.1e-17 64.2 1.2 1.1e-17 64.2 1.2 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif NRN1 PF15056.6 GAN06951.1 - 0.052 13.7 0.1 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 Neuritin protein family PDGF_N PF04692.13 GAN06951.1 - 0.4 11.5 6.9 5.4 7.9 0.6 4.4 3 0 0 3 3 3 0 Platelet-derived growth factor, N terminal region Shugoshin_C PF07557.11 GAN06952.1 - 1e-05 25.2 0.9 1.7e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 Shugoshin C terminus GIT_CC PF16559.5 GAN06952.1 - 1.9e-05 24.4 2.2 3.4e-05 23.6 2.2 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Shugoshin_N PF07558.11 GAN06952.1 - 0.00011 22.0 8.7 0.00021 21.1 8.7 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 GAN06952.1 - 0.13 12.5 7.0 0.25 11.5 7.0 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 GAN06952.1 - 0.33 11.5 3.7 0.12 12.9 1.3 1.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4609 PF15382.6 GAN06952.1 - 0.42 10.5 3.8 2.4 8.1 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4609) YebO PF13974.6 GAN06952.1 - 0.42 10.7 6.3 0.82 9.8 6.3 1.6 1 1 0 1 1 1 0 YebO-like protein Nucleotid_trans PF03407.16 GAN06953.1 - 3.8e-08 33.6 0.0 6.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase NESP55 PF06390.12 GAN06953.1 - 0.024 14.2 4.7 0.04 13.5 4.7 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Med29 PF11568.8 GAN06953.1 - 0.035 14.3 0.2 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 29 UDPGP PF01704.18 GAN06954.1 - 6e-57 193.2 0.0 7.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 GAN06954.1 - 0.045 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Gln-synt_C PF00120.24 GAN06955.1 - 2.3e-82 276.8 0.0 2.8e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Cyt-b5 PF00173.28 GAN06956.1 - 2.5e-26 91.6 0.0 3.8e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PhoU_div PF01865.16 GAN06957.1 - 0.04 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 GCR1_C PF12550.8 GAN06958.1 - 0.00019 21.7 0.6 0.00032 21.0 0.1 1.7 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Nuc_sug_transp PF04142.15 GAN06959.1 - 2.3e-06 27.0 1.0 1.6e-05 24.3 1.0 2.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter UPF0220 PF05255.11 GAN06959.1 - 0.047 13.2 3.1 0.095 12.2 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0220) PrgI PF12666.7 GAN06959.1 - 0.66 10.7 5.2 2.1 9.1 0.1 3.3 3 1 0 3 3 3 0 PrgI family protein EamA PF00892.20 GAN06959.1 - 4.6 7.4 26.4 0.1 12.8 4.6 3.4 4 0 0 4 4 4 0 EamA-like transporter family DUF572 PF04502.13 GAN06961.1 - 4.9e-78 263.1 5.6 5.8e-78 262.8 5.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1676 PF07898.13 GAN06961.1 - 0.031 14.3 1.4 0.056 13.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) FixH PF05751.11 GAN06961.1 - 0.13 12.3 0.3 0.22 11.5 0.3 1.3 1 0 0 1 1 1 0 FixH Esterase_phd PF10503.9 GAN06961.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase CAS_C PF12026.8 GAN06961.1 - 2.3 8.3 9.5 2.3 8.3 8.4 1.5 1 1 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Sugar_tr PF00083.24 GAN06962.1 - 8.8e-101 338.0 35.8 1.4e-51 175.8 17.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN06962.1 - 9.4e-24 84.0 55.4 1.3e-21 76.9 30.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 GAN06962.1 - 0.37 9.1 11.5 0.48 8.7 3.8 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector PRIMA1 PF16101.5 GAN06962.1 - 7.5 6.6 7.7 5.4 7.1 2.1 2.8 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 GIT_SHD PF08518.11 GAN06963.1 - 1.3e-26 91.8 5.3 8.5e-14 50.9 0.4 3.6 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT ANAPC8 PF04049.13 GAN06963.1 - 1.1e-18 67.6 1.2 1.1e-18 67.6 1.2 3.4 2 1 1 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 GAN06963.1 - 8.8e-16 56.7 19.2 0.0018 18.2 0.7 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN06963.1 - 2.2e-15 55.7 21.5 0.0031 17.3 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAN06963.1 - 2.3e-10 40.6 12.2 0.00042 20.6 2.0 5.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN06963.1 - 4e-10 39.1 15.9 0.66 10.3 0.3 7.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06963.1 - 4.9e-08 33.4 6.9 0.0016 18.9 1.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN06963.1 - 9.7e-08 32.2 13.5 0.0013 19.4 0.6 6.2 4 1 2 6 6 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN06963.1 - 9.3e-06 25.7 6.7 0.068 13.6 0.7 6.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN06963.1 - 4.8e-05 23.1 9.5 0.37 10.9 0.3 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN06963.1 - 0.00054 20.5 13.0 0.12 13.0 1.0 5.8 3 2 2 5 5 5 2 Tetratricopeptide repeat APG6_N PF17675.1 GAN06963.1 - 0.0041 17.7 18.2 0.0041 17.7 18.2 3.0 3 1 0 3 3 1 1 Apg6 coiled-coil region TPR_11 PF13414.6 GAN06963.1 - 0.0074 16.0 16.2 0.38 10.5 0.6 5.3 3 2 2 5 5 4 2 TPR repeat CALCOCO1 PF07888.11 GAN06963.1 - 0.0086 15.0 13.9 0.02 13.8 13.9 1.5 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like VBS PF08913.10 GAN06963.1 - 0.009 16.5 5.5 5.4 7.5 1.6 3.8 2 1 1 3 3 3 0 Vinculin Binding Site GIT1_C PF12205.8 GAN06963.1 - 0.014 15.5 6.6 0.025 14.7 0.3 3.2 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF724 PF05266.14 GAN06963.1 - 0.014 15.2 12.0 0.045 13.6 12.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tropomyosin PF00261.20 GAN06963.1 - 0.015 14.7 14.3 0.043 13.2 14.3 1.7 1 0 0 1 1 1 0 Tropomyosin DUF4164 PF13747.6 GAN06963.1 - 0.024 14.9 3.5 0.095 13.0 3.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) YabA PF06156.13 GAN06963.1 - 0.029 15.0 7.4 0.22 12.2 7.4 2.7 1 0 0 1 1 1 0 Initiation control protein YabA TPR_6 PF13174.6 GAN06963.1 - 0.032 14.9 16.3 6.9 7.5 0.0 7.0 6 0 0 6 6 5 0 Tetratricopeptide repeat ZapB PF06005.12 GAN06963.1 - 0.13 12.7 22.9 0.31 11.5 9.3 3.7 2 1 1 3 3 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 GAN06963.1 - 0.17 11.9 18.2 0.082 12.9 9.0 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 GAN06963.1 - 0.26 11.3 17.6 0.15 12.1 11.6 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Swi5 PF07061.11 GAN06963.1 - 0.45 10.6 10.7 0.4 10.8 4.1 3.2 2 0 0 2 2 2 0 Swi5 FUSC PF04632.12 GAN06963.1 - 0.74 8.3 8.1 3.4 6.1 0.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family bZIP_1 PF00170.21 GAN06963.1 - 0.89 9.7 12.9 20 5.4 12.7 3.0 1 1 1 2 2 2 0 bZIP transcription factor TPR_10 PF13374.6 GAN06963.1 - 1.3 8.9 9.7 24 5.0 0.3 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3450 PF11932.8 GAN06963.1 - 1.4 8.2 17.0 1.2 8.4 14.2 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 GAN06963.1 - 1.6 8.0 23.0 0.17 11.2 16.4 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 GAN06963.1 - 2.3 8.3 11.0 6.7 6.8 5.9 3.6 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Enkurin PF13864.6 GAN06963.1 - 2.7 8.5 13.9 3.8 8.0 9.0 3.4 3 0 0 3 3 2 0 Calmodulin-binding ERM PF00769.19 GAN06963.1 - 6.4 6.5 24.5 0.026 14.4 11.1 3.0 3 0 0 3 3 3 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 GAN06963.1 - 8.1 6.5 16.1 42 4.2 16.0 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 GAN06963.1 - 8.4 6.7 17.4 3.2 8.0 10.9 3.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MFS_1 PF07690.16 GAN06965.1 - 1.1e-32 113.3 52.0 3.4e-29 101.9 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.6 GAN06966.1 - 3.4e-12 45.9 23.9 6.2e-08 32.3 11.8 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAN06966.1 - 5.6e-11 42.5 20.7 1.1e-05 25.6 2.8 3.1 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAN06966.1 - 0.0002 20.9 5.3 0.01 15.3 1.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 GAN06966.1 - 0.081 13.5 23.9 3.7 8.5 0.1 6.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 GAN06966.1 - 2.8 8.2 8.3 7.4 6.9 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich repeat Velvet PF11754.8 GAN06969.1 - 2.7e-42 145.5 6.8 3.3e-31 109.1 0.1 3.1 2 1 1 3 3 3 2 Velvet factor RXT2_N PF08595.11 GAN06969.1 - 0.0052 16.8 2.2 0.0099 15.9 2.2 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal Ras PF00071.22 GAN06971.1 - 1.4e-36 125.5 0.0 1.6e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN06971.1 - 2.6e-12 47.0 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN06971.1 - 0.063 12.7 0.0 0.084 12.3 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family DAO PF01266.24 GAN06972.1 - 2.2e-52 178.8 0.0 3.1e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Polysacc_synt_4 PF04669.13 GAN06972.1 - 2.1e-17 63.3 2.0 3.7e-16 59.2 2.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis Pyr_redox_2 PF07992.14 GAN06972.1 - 7.9e-06 25.3 1.6 0.0017 17.7 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAN06972.1 - 4.6e-05 22.8 0.0 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAN06972.1 - 0.00016 21.8 0.1 0.00038 20.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAN06972.1 - 0.0088 15.2 0.5 0.026 13.6 0.3 1.9 2 1 0 2 2 2 1 FAD binding domain Mqo PF06039.15 GAN06972.1 - 0.014 14.0 0.0 0.034 12.7 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Sacchrp_dh_NADP PF03435.18 GAN06972.1 - 0.018 15.3 0.2 0.08 13.2 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 GAN06972.1 - 0.027 13.7 0.2 0.15 11.3 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 GAN06972.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAN06972.1 - 0.11 11.5 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 GAN06972.1 - 0.12 11.2 0.2 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 GAN06972.1 - 0.13 12.5 0.6 0.27 11.5 0.2 1.7 2 0 0 2 2 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 GAN06972.1 - 0.15 11.3 0.2 0.51 9.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Clathrin PF00637.20 GAN06973.1 - 1.9e-26 92.6 4.7 8.7e-26 90.5 0.9 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 GAN06973.1 - 0.00032 21.1 0.9 0.0025 18.2 0.1 2.6 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 2 WD40 PF00400.32 GAN06973.1 - 0.00062 20.5 0.1 0.0031 18.3 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_5 PF14634.6 GAN06973.1 - 0.00066 19.6 2.4 0.0017 18.3 2.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAN06973.1 - 0.034 14.5 6.4 0.27 11.6 6.4 2.4 1 1 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 GAN06973.1 - 0.043 13.9 0.6 1.3 9.1 0.3 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_11 PF17123.5 GAN06973.1 - 0.34 10.7 3.2 0.78 9.5 3.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 GAN06973.1 - 0.53 10.4 5.2 0.084 12.9 0.7 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 GAN06973.1 - 1.2 9.4 8.1 1.1 9.7 3.0 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 GAN06973.1 - 6.2 6.9 5.5 11 6.1 2.6 2.6 2 1 0 2 2 2 0 Zinc-finger Glyco_hydro_18 PF00704.28 GAN06974.1 - 1.5e-71 241.7 1.3 1.7e-71 241.5 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 GAN06975.1 - 7.9e-24 84.4 0.0 1.3e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN06975.1 - 1.7e-17 63.6 0.1 3.9e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Rad60-SLD PF11976.8 GAN06976.1 - 6.3e-20 70.8 1.3 5.2e-14 51.8 0.3 2.8 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like PBP PF01161.20 GAN06976.1 - 3.3e-05 24.2 0.0 0.00022 21.6 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein DUF3580 PF12117.8 GAN06976.1 - 0.18 12.0 2.4 0.45 10.8 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Erf4 PF10256.9 GAN06977.1 - 5e-32 110.4 3.7 7.1e-32 109.9 0.9 2.0 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family RabGAP-TBC PF00566.18 GAN06979.1 - 1.6e-53 181.6 0.7 1.6e-53 181.6 0.7 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mod_r PF07200.13 GAN06979.1 - 8.9e-06 25.9 18.6 0.0072 16.4 5.7 2.7 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 GAN06979.1 - 0.013 15.5 21.4 0.025 14.6 21.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3150 PF11348.8 GAN06979.1 - 0.013 14.7 1.1 0.028 13.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) HAV_VP PF12944.7 GAN06979.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP DegS PF05384.11 GAN06979.1 - 0.14 11.7 13.2 0.31 10.5 12.6 1.9 1 1 0 1 1 1 0 Sensor protein DegS TMF_TATA_bd PF12325.8 GAN06979.1 - 1 9.6 20.5 5.3 7.3 15.2 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 GAN06979.1 - 1.1 9.8 18.6 0.6 10.6 15.4 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region ZYG-11_interact PF05884.12 GAN06979.1 - 1.3 8.3 3.7 2.5 7.4 3.7 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 UPF0242 PF06785.11 GAN06979.1 - 2 8.5 18.6 0.6 10.2 13.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 GAN06979.1 - 5.6 6.1 10.6 11 5.2 10.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein Nup54 PF13874.6 GAN06979.1 - 5.8 7.0 13.0 2.8 8.1 10.3 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3450 PF11932.8 GAN06979.1 - 8.5 5.6 20.6 3.3 6.9 7.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 GAN06979.1 - 8.9 6.4 9.2 1.3 9.1 4.3 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_primase_lrg PF04104.14 GAN06980.1 - 1.2e-84 283.8 0.2 1.2e-84 283.8 0.2 1.9 2 1 1 3 3 3 1 Eukaryotic and archaeal DNA primase, large subunit DUF5301 PF17225.3 GAN06980.1 - 0.032 14.7 0.1 0.15 12.5 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) WD40 PF00400.32 GAN06981.1 - 2.3e-10 40.9 19.9 0.0032 18.3 0.5 6.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 GAN06981.1 - 3.5e-09 36.2 18.9 3.5e-09 36.2 18.9 2.6 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_2 PF13240.6 GAN06981.1 - 0.0031 17.2 9.3 0.023 14.4 2.2 2.6 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 GAN06981.1 - 0.0036 17.3 10.9 0.0078 16.2 10.9 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_16 PF17034.5 GAN06981.1 - 0.0043 17.3 16.5 0.023 14.9 16.4 2.1 1 1 1 2 2 2 1 Zinc-ribbon like family RWD PF05773.22 GAN06981.1 - 0.0065 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 RWD domain ANAPC4_WD40 PF12894.7 GAN06981.1 - 0.032 14.5 1.4 2.2 8.6 0.1 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain rve PF00665.26 GAN06981.1 - 0.063 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Rad52_Rad22 PF04098.15 GAN06982.1 - 4.7e-43 146.8 0.0 8.6e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein F-protein PF00469.20 GAN06982.1 - 0.0011 18.6 0.1 0.0036 16.9 0.0 1.8 2 0 0 2 2 2 1 Negative factor, (F-Protein) or Nef Ndc1_Nup PF09531.10 GAN06982.1 - 2.1 6.9 9.0 2.7 6.6 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 GAN06982.1 - 2.1 8.2 12.4 2.7 7.9 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HMA PF00403.26 GAN06983.1 - 1.9e-57 191.5 2.7 8.4e-14 51.8 0.1 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 GAN06983.1 - 2.7e-43 147.6 2.8 9.7e-43 145.8 2.8 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAN06983.1 - 1.5e-38 133.2 0.6 1.4e-37 130.1 0.6 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN06983.1 - 0.00046 20.0 4.8 0.0074 16.1 1.0 2.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN06983.1 - 0.02 15.3 0.0 0.066 13.6 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 GAN06983.1 - 0.061 13.7 6.9 20 5.6 0.1 4.7 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain GFA PF04828.14 GAN06983.1 - 0.9 9.9 6.7 2.3 8.6 0.6 3.7 3 1 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme Metallophos PF00149.28 GAN06984.1 - 2.6e-37 129.3 0.4 3.4e-37 128.9 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN06984.1 - 1.8e-05 25.1 0.1 3.5e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain cwf21 PF08312.12 GAN06984.1 - 0.11 12.6 1.6 0.2 11.9 1.6 1.4 1 0 0 1 1 1 0 cwf21 domain SNF2_N PF00176.23 GAN06985.1 - 4.4e-67 226.3 3.0 4.4e-67 226.3 3.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 GAN06985.1 - 8.4e-21 73.8 1.6 2.7e-20 72.2 1.6 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 GAN06985.1 - 8.6e-14 51.8 0.5 3.4e-12 46.7 0.0 3.4 3 1 1 4 4 4 1 Helicase conserved C-terminal domain QLQ PF08880.11 GAN06985.1 - 2.1e-10 40.2 6.0 7.1e-10 38.5 6.0 2.0 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 GAN06985.1 - 3e-10 40.4 0.1 3e-10 40.4 0.1 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 GAN06985.1 - 9.4e-09 35.5 10.9 9.4e-09 35.5 10.9 3.2 2 1 1 3 3 3 1 HSA SnAC PF14619.6 GAN06985.1 - 7.6e-05 23.2 0.2 7.6e-05 23.2 0.2 3.1 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex AAA_14 PF13173.6 GAN06985.1 - 0.05 13.7 0.2 0.81 9.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF3292 PF11696.8 GAN06987.1 - 1.5e-13 50.1 10.4 4.1e-10 38.7 0.1 3.5 2 2 1 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 GAN06987.1 - 7.7e-05 22.5 0.7 0.00027 20.7 0.1 2.1 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal UTP25 PF06862.12 GAN06987.1 - 0.074 11.8 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Reticulon PF02453.17 GAN06987.1 - 0.13 12.2 2.3 0.56 10.2 0.3 2.3 2 0 0 2 2 2 0 Reticulon Proteasome PF00227.26 GAN06988.1 - 2.7e-45 154.2 0.0 3e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Thioredoxin_4 PF13462.6 GAN06989.1 - 4.4e-11 43.2 0.0 6.8e-11 42.6 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 GAN06989.1 - 0.0019 18.0 1.6 1.1 9.0 0.5 2.2 1 1 0 2 2 2 2 DSBA-like thioredoxin domain YdaS_antitoxin PF15943.5 GAN06989.1 - 0.15 11.9 1.1 0.55 10.1 0.1 2.2 2 1 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pro_isomerase PF00160.21 GAN06990.1 - 3.8e-49 167.0 0.1 6.1e-49 166.3 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 GAN06990.1 - 6.8e-13 47.7 0.5 0.00045 20.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN06990.1 - 2.7e-09 36.4 1.0 0.0035 17.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN06990.1 - 2.3e-06 27.2 3.4 0.0023 17.6 1.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 GAN06990.1 - 4.1e-06 26.6 0.1 0.018 15.2 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06990.1 - 0.011 16.2 0.1 11 6.6 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAN06990.1 - 0.041 13.9 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PapD-like PF14874.6 GAN06990.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like Fis1_TPR_C PF14853.6 GAN06990.1 - 0.13 12.3 1.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat RVT_1 PF00078.27 GAN06991.1 - 1.4e-40 139.2 0.0 3.5e-40 137.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GAN06991.1 - 5.6e-13 49.4 0.5 2.7e-12 47.2 0.4 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 GAN06991.1 - 0.012 15.1 0.1 0.11 12.0 0.0 2.4 2 1 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family MIP-T3_C PF17749.1 GAN06991.1 - 0.2 11.6 0.5 0.37 10.7 0.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region MSA-2c PF12238.8 GAN06992.1 - 0.14 12.1 2.1 0.26 11.3 2.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Sugarporin_N PF11471.8 GAN06992.1 - 0.17 11.8 0.3 3.3 7.7 0.3 2.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension CBS PF00571.28 GAN06993.1 - 5.7e-27 93.9 0.5 5.4e-06 26.7 0.1 4.3 4 0 0 4 4 4 4 CBS domain FPV060 PF17614.2 GAN06993.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Viral CC-type chemokine Herpes_Helicase PF02689.14 GAN06994.1 - 1.6e-06 26.4 0.0 1.7e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 GAN06994.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PHO4 PF01384.20 GAN06995.1 - 1.7e-119 398.9 22.8 2e-119 398.6 22.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family Cytochrom_B_C PF00032.17 GAN06995.1 - 0.019 15.2 1.8 0.09 13.1 1.8 2.3 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD LapA_dom PF06305.11 GAN06995.1 - 0.022 14.6 0.3 0.022 14.6 0.3 4.2 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Transmemb_17 PF09799.9 GAN06995.1 - 3.5 8.2 8.5 2.1 9.0 3.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein Nro1 PF12753.7 GAN06996.1 - 2.5e-17 63.0 20.0 1e-16 61.0 1.3 2.1 1 1 1 2 2 2 2 Nuclear pore complex subunit Nro1 TPR_16 PF13432.6 GAN06996.1 - 0.00022 21.8 11.6 0.39 11.4 0.0 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN06996.1 - 0.0036 18.0 9.6 2.7 9.0 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN06996.1 - 0.013 15.8 1.4 11 6.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAN06996.1 - 0.66 10.5 0.1 0.66 10.5 0.1 4.8 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAN06996.1 - 4.3 7.1 9.0 1.3 8.8 0.1 4.0 5 0 0 5 5 5 0 TPR repeat Mit_ribos_Mrp51 PF11709.8 GAN06996.1 - 4.8 6.7 6.8 8.7 5.8 6.4 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit GATase_6 PF13522.6 GAN06997.1 - 4.8e-15 55.9 0.0 9.7e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAN06997.1 - 6.8e-13 48.6 0.0 1.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAN06997.1 - 1.4e-06 27.4 0.0 3.1e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 GAN06997.1 - 5.7e-06 25.9 0.0 9.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF2118 PF09891.9 GAN06997.1 - 0.11 12.4 0.5 0.62 10.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Cullin PF00888.22 GAN06998.1 - 1.6e-151 506.0 14.7 3.4e-151 504.9 14.7 1.5 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAN06998.1 - 4.9e-19 68.1 1.7 4.9e-19 68.1 1.7 3.2 3 0 0 3 3 3 1 Cullin protein neddylation domain TRAPPC10 PF12584.8 GAN06998.1 - 6.8e-19 68.1 0.0 2.1e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF5398 PF17376.2 GAN06998.1 - 0.0022 18.6 4.6 2.8 8.6 0.0 4.2 3 0 0 3 3 3 2 Family of unknown function (DUF5398) T6SS_VasJ PF16989.5 GAN06998.1 - 0.084 12.3 0.2 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Gryzun-like PF12742.7 GAN06998.1 - 0.084 12.9 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking WAC_Acf1_DNA_bd PF10537.9 GAN06998.1 - 0.37 11.3 3.2 2.9 8.5 0.3 3.7 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal Macoilin PF09726.9 GAN06999.1 - 3.8 5.9 14.4 7.2 5.0 13.9 1.7 1 1 0 1 1 1 0 Macoilin family Ank_2 PF12796.7 GAN07000.1 - 1.1e-18 67.6 3.8 1.6e-08 35.0 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN07000.1 - 1.3e-14 54.3 0.7 2.1e-10 40.9 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAN07000.1 - 4.7e-12 45.8 0.4 0.0013 19.1 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 GAN07000.1 - 1.5e-10 40.4 0.4 0.045 14.3 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAN07000.1 - 2.5e-09 37.2 0.3 0.0097 16.2 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Rad60-SLD_2 PF13881.6 GAN07000.1 - 0.082 13.0 0.9 0.24 11.5 0.9 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1129 PF06570.11 GAN07001.1 - 0.014 14.9 1.5 0.014 14.9 1.5 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 GAN07001.1 - 0.076 12.7 0.4 0.076 12.7 0.4 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Shisa PF13908.6 GAN07001.1 - 3.5 7.8 5.0 14 5.9 0.0 3.1 3 1 0 3 3 3 0 Wnt and FGF inhibitory regulator Glyco_transf_15 PF01793.16 GAN07002.1 - 1.7e-112 375.9 8.4 2.1e-112 375.6 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DRAT PF07357.11 GAN07003.1 - 0.089 12.0 0.4 0.11 11.6 0.3 1.3 1 1 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DUF2052 PF09747.9 GAN07004.1 - 4.3e-35 121.6 31.1 4.3e-35 121.6 31.1 1.8 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) HSF_DNA-bind PF00447.17 GAN07006.1 - 8.4e-35 119.3 1.3 2e-34 118.1 1.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Cdc6_C PF09079.11 GAN07006.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RhoGEF PF00621.20 GAN07007.1 - 3.1e-31 109.0 1.9 3.1e-31 109.0 1.9 2.5 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 GAN07007.1 - 0.0041 17.6 0.0 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 GAN07007.1 - 0.0088 16.0 2.3 0.078 12.9 0.1 3.1 3 0 0 3 3 3 1 PH domain PH_10 PF15411.6 GAN07007.1 - 0.032 14.5 0.1 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain LSR PF05624.14 GAN07008.1 - 0.0066 16.4 8.8 0.01 15.8 8.8 1.2 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) DUF4096 PF13340.6 GAN07008.1 - 0.0079 16.4 0.9 0.36 11.1 0.2 2.2 1 1 1 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) Herpes_gE PF02480.16 GAN07008.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Prominin PF05478.11 GAN07008.1 - 0.2 9.6 1.7 0.24 9.3 1.7 1.1 1 0 0 1 1 1 0 Prominin GFO_IDH_MocA PF01408.22 GAN07010.1 - 7.6e-23 81.6 0.7 9.1e-23 81.4 0.7 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 GAN07010.1 - 3.6e-05 24.3 1.0 0.00022 21.7 1.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 GAN07010.1 - 0.0042 17.7 0.4 0.0054 17.4 0.4 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAN07010.1 - 0.0063 16.6 0.2 0.014 15.5 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rhodanese PF00581.20 GAN07010.1 - 0.05 14.1 0.1 0.11 13.1 0.0 1.5 2 0 0 2 2 2 0 Rhodanese-like domain p450 PF00067.22 GAN07011.1 - 2.4e-48 165.0 0.1 3.4e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Y_phosphatase2 PF03162.13 GAN07012.1 - 3.3e-55 186.1 0.0 3.6e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAN07012.1 - 0.0003 20.8 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAN07012.1 - 0.022 14.3 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S6e PF01092.19 GAN07013.1 - 1.6e-23 83.0 2.2 2.1e-23 82.6 0.1 2.0 1 1 0 2 2 2 1 Ribosomal protein S6e BTB_2 PF02214.22 GAN07014.1 - 0.00013 22.2 0.3 0.00038 20.7 0.0 1.9 3 0 0 3 3 3 1 BTB/POZ domain DUF1247 PF06851.11 GAN07014.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) Thiolase_N PF00108.23 GAN07015.1 - 8.9e-87 290.7 0.0 1.5e-86 290.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN07015.1 - 1.1e-46 157.5 1.7 1.6e-46 156.9 0.5 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAN07015.1 - 3.6e-06 26.7 0.2 1.5e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.26 GAN07016.1 - 9e-49 164.7 0.0 1.1e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAN07016.1 - 0.0025 17.5 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAN07016.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 GAN07016.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain tRNA_anti-codon PF01336.25 GAN07017.1 - 2.8e-05 24.0 0.1 5.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 GAN07017.1 - 0.00028 21.5 0.1 0.00044 20.9 0.1 1.3 1 0 0 1 1 1 1 Replication protein A C terminal TBPIP PF07106.13 GAN07017.1 - 0.022 14.7 0.2 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain Ras PF00071.22 GAN07018.1 - 1.5e-55 187.2 0.1 1.8e-55 187.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN07018.1 - 1.5e-27 96.2 0.1 3.9e-27 94.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN07018.1 - 4.1e-11 42.7 0.1 5.1e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN07018.1 - 0.0042 16.7 0.0 0.0075 15.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN07018.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PRORP PF16953.5 GAN07018.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P RCR PF12273.8 GAN07019.1 - 0.013 16.2 0.1 0.013 16.2 0.1 2.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.6 GAN07019.1 - 0.028 14.3 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF4448 PF14610.6 GAN07019.1 - 0.042 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 GAN07019.1 - 0.1 12.0 0.3 0.23 10.9 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain OAD_gamma PF04277.13 GAN07019.1 - 0.13 12.8 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PspB PF06667.12 GAN07019.1 - 0.17 12.0 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Phage shock protein B WBP-1 PF11669.8 GAN07019.1 - 0.3 11.8 5.7 0.34 11.6 3.5 2.0 1 1 1 2 2 2 0 WW domain-binding protein 1 Comm PF15957.5 GAN07019.1 - 4.1 7.8 5.1 40 4.6 5.1 2.1 1 1 0 1 1 1 0 Commissureless TP6A_N PF04406.14 GAN07020.1 - 1e-12 47.8 0.2 2.5e-12 46.6 0.2 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase EMC3_TMCO1 PF01956.16 GAN07021.1 - 8e-52 175.4 0.6 8e-52 175.4 0.6 1.8 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Lsm_interact PF05391.11 GAN07021.1 - 0.5 9.9 2.5 1.2 8.7 2.5 1.7 1 0 0 1 1 1 0 Lsm interaction motif Asp PF00026.23 GAN07022.1 - 1.6e-87 293.9 0.0 1.9e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN07022.1 - 1.2e-15 58.2 0.4 1.4e-09 38.4 0.1 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN07022.1 - 0.014 16.1 0.2 4.9 7.9 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease Ldh_1_N PF00056.23 GAN07023.1 - 5.1e-15 55.8 0.0 9.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAN07023.1 - 0.0096 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAN07023.1 - 0.043 13.4 0.5 0.2 11.2 0.5 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 GAN07023.1 - 0.12 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 GAN07023.1 - 0.24 10.7 1.1 0.52 9.6 0.1 1.9 2 1 0 2 2 2 0 ThiF family PDEase_I PF00233.19 GAN07025.1 - 3.1e-69 233.3 8.9 4.7e-69 232.7 8.9 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 GAN07025.1 - 1.3e-07 31.9 0.1 5.2e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 HD domain HD_6 PF18019.1 GAN07025.1 - 0.041 14.0 0.9 0.14 12.3 0.9 2.1 1 1 0 1 1 1 0 HD domain Malic_M PF03949.15 GAN07026.1 - 1.2e-80 270.5 0.2 1.6e-80 270.1 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAN07026.1 - 2.5e-58 196.9 0.0 8.7e-58 195.1 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain IFT20 PF14931.6 GAN07026.1 - 0.13 12.5 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 zf-RING_2 PF13639.6 GAN07027.1 - 1.6e-11 44.3 8.3 1.6e-11 44.3 8.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN07027.1 - 1.3e-09 37.7 8.4 1.3e-09 37.7 8.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN07027.1 - 8.2e-08 32.0 9.4 8.2e-08 32.0 9.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN07027.1 - 1.8e-07 30.7 5.3 5.8e-07 29.2 5.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAN07027.1 - 2.1e-07 31.1 10.0 2.1e-07 31.1 10.0 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAN07027.1 - 3.7e-07 29.9 4.2 3.7e-07 29.9 4.2 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN07027.1 - 2.5e-06 27.5 3.0 2.5e-06 27.5 3.0 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAN07027.1 - 2.8e-05 24.0 5.5 0.00018 21.5 5.4 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAN07027.1 - 0.00012 22.0 5.9 0.00012 22.0 5.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN07027.1 - 0.0008 19.2 6.4 0.0008 19.2 6.4 2.1 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GAN07027.1 - 0.0042 16.9 2.8 0.0042 16.9 2.8 2.3 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 GAN07027.1 - 0.035 14.2 3.6 0.035 14.2 3.6 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 RINGv PF12906.7 GAN07027.1 - 0.085 13.0 5.5 0.26 11.5 5.5 1.8 1 1 0 1 1 1 0 RING-variant domain Spt4 PF06093.13 GAN07027.1 - 4 7.6 5.9 0.87 9.7 0.3 2.5 3 0 0 3 3 2 0 Spt4/RpoE2 zinc finger zf-C2HC5 PF06221.13 GAN07027.1 - 5.1 7.2 14.7 0.11 12.5 1.1 2.7 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type Zn_clus PF00172.18 GAN07028.1 - 1.1e-05 25.4 12.6 2e-05 24.6 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAN07028.1 - 0.0022 17.1 0.7 0.0022 17.1 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain ISP1_C PF18161.1 GAN07028.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 ISP1 C-terminal OCD_Mu_crystall PF02423.15 GAN07029.1 - 4.8e-56 190.0 2.1 5.7e-56 189.8 2.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAN07029.1 - 5.1e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 GAN07029.1 - 0.013 16.3 0.0 0.036 14.9 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 GAN07029.1 - 0.094 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding TRIC PF05197.13 GAN07030.1 - 0.00043 19.9 0.7 0.00062 19.4 0.7 1.3 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 GAN07030.1 - 0.0028 17.5 3.3 0.054 13.4 0.6 2.3 2 0 0 2 2 2 2 UPF0126 domain UVR PF02151.19 GAN07032.1 - 0.0016 18.1 7.0 0.023 14.5 0.2 3.0 2 0 0 2 2 2 2 UvrB/uvrC motif HEAT PF02985.22 GAN07032.1 - 0.0053 16.9 0.0 0.4 11.1 0.0 2.9 2 0 0 2 2 2 1 HEAT repeat 5_3_exonuc PF01367.20 GAN07032.1 - 0.25 12.0 2.7 0.72 10.5 0.0 3.2 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold zf-Di19 PF05605.12 GAN07032.1 - 1.3 9.3 11.7 9.6 6.6 3.4 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 GAN07032.1 - 1.3 9.1 5.1 11 6.1 0.0 3.6 3 0 0 3 3 3 0 BED zinc finger ABC_trans_N PF14510.6 GAN07032.1 - 1.7 9.3 7.7 0.36 11.5 2.3 2.6 2 0 0 2 2 2 0 ABC-transporter N-terminal DUF3246 PF11596.8 GAN07033.1 - 0.016 14.7 0.2 0.025 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NolV PF06635.12 GAN07033.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein NolV Tetraspanin PF00335.20 GAN07034.1 - 3.2e-12 46.6 15.1 5.4e-12 45.9 15.1 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 GAN07034.1 - 0.022 14.5 4.0 0.63 9.7 5.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Wzy_C PF04932.15 GAN07034.1 - 0.17 11.5 3.3 0.17 11.5 1.8 1.9 1 1 0 1 1 1 0 O-Antigen ligase ABC2_membrane_3 PF12698.7 GAN07034.1 - 0.52 9.4 11.8 0.68 9.0 11.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4191 PF13829.6 GAN07034.1 - 1.5 8.1 3.9 2.9 7.2 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Arteri_Gl PF00951.18 GAN07034.1 - 5.4 6.8 7.9 0.96 9.2 3.5 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF4407 PF14362.6 GAN07034.1 - 8.5 5.6 6.5 17 4.6 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kelch_6 PF13964.6 GAN07035.1 - 1.9e-15 56.5 3.2 0.0077 16.5 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAN07035.1 - 3.9e-14 52.4 3.9 1.6e-05 24.8 0.3 4.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN07035.1 - 5e-12 45.5 5.5 3.1e-05 23.9 0.3 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GAN07035.1 - 2.6e-11 43.0 13.1 3.3e-05 23.7 0.4 5.9 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 GAN07035.1 - 2.9e-08 33.8 3.1 0.025 14.9 0.2 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain F-box PF00646.33 GAN07035.1 - 0.0019 18.0 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain Kelch_1 PF01344.25 GAN07035.1 - 0.11 12.1 28.0 0.19 11.3 0.9 6.0 6 2 0 6 6 6 0 Kelch motif Zn_clus PF00172.18 GAN07036.1 - 0.00019 21.5 11.1 0.00044 20.3 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 GAN07036.1 - 1.6 8.3 17.2 3.4 7.2 4.7 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TMEM223 PF14640.6 GAN07037.1 - 1.1e-45 155.8 0.0 1.6e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 PhoH PF02562.16 GAN07037.1 - 0.0045 16.5 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Cu-oxidase_3 PF07732.15 GAN07038.1 - 1.8e-10 40.9 0.6 5.4e-10 39.3 0.6 1.7 1 1 0 1 1 1 1 Multicopper oxidase DUF4462 PF14692.6 GAN07038.1 - 1.1 8.7 0.0 1.1 8.7 0.0 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4462) CRAL_TRIO PF00650.20 GAN07040.1 - 2.7e-36 124.7 0.0 4e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN07040.1 - 5.5e-11 42.5 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAN07040.1 - 1.5e-05 25.2 0.1 3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_hydro_18 PF00704.28 GAN07041.1 - 8.6e-69 232.6 9.7 8.6e-69 232.6 9.7 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Radical_SAM PF04055.21 GAN07041.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily Mucin PF01456.17 GAN07041.1 - 0.17 11.9 10.2 0.31 11.0 10.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FliP PF00813.20 GAN07041.1 - 0.22 11.4 0.5 0.41 10.5 0.5 1.4 1 0 0 1 1 1 0 FliP family Connexin PF00029.19 GAN07041.1 - 0.23 11.2 4.0 0.37 10.5 4.0 1.2 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 GAN07041.1 - 0.31 9.7 2.6 0.47 9.1 2.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier EOS1 PF12326.8 GAN07041.1 - 0.5 10.3 8.8 1 9.3 8.8 1.4 1 0 0 1 1 1 0 N-glycosylation protein Ureide_permease PF07168.11 GAN07041.1 - 0.56 8.9 4.1 0.92 8.2 4.1 1.3 1 0 0 1 1 1 0 Ureide permease Peptidase_S49_N PF08496.10 GAN07041.1 - 0.57 10.2 5.8 1.1 9.4 5.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal IgaA PF07095.11 GAN07041.1 - 0.69 7.8 3.3 1.1 7.2 3.3 1.2 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF4834 PF16118.5 GAN07041.1 - 0.78 10.7 4.0 1.6 9.7 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SR-25 PF10500.9 GAN07041.1 - 5.5 6.5 19.8 12 5.4 19.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRP36 PF06102.12 GAN07042.1 - 4.3e-50 169.9 30.1 4.3e-50 169.9 30.1 2.4 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 Glyco_transf_8 PF01501.20 GAN07042.1 - 0.96 8.9 4.4 0.16 11.5 0.4 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 8 DUF1748 PF08520.10 GAN07043.1 - 1.4e-28 98.6 0.0 1.8e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Pcc1 PF09341.10 GAN07044.1 - 7.7e-22 77.2 0.2 8.4e-22 77.1 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Ras PF00071.22 GAN07045.1 - 6.1e-55 185.2 0.1 7e-55 185.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN07045.1 - 9.7e-21 74.2 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN07045.1 - 8.2e-09 35.1 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN07045.1 - 2.6e-06 27.1 0.3 6.3e-06 25.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN07045.1 - 9.1e-05 22.5 0.1 0.00013 22.0 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN07045.1 - 0.00039 20.4 0.6 0.51 10.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 GAN07045.1 - 0.0016 17.6 0.2 0.45 9.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit LRR_4 PF12799.7 GAN07046.1 - 7.1e-05 23.1 14.3 0.039 14.4 0.4 5.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAN07046.1 - 0.019 14.8 8.4 0.41 10.4 0.3 4.0 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 GAN07046.1 - 2.3 8.5 11.5 9.6 6.5 1.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat DUF2373 PF10180.9 GAN07047.1 - 6.9e-18 64.3 1.1 1.4e-17 63.2 1.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Polysacc_deac_1 PF01522.21 GAN07047.1 - 4.6e-12 45.9 0.1 1.3e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1943 PF09172.11 GAN07047.1 - 0.0013 18.0 7.9 0.0032 16.8 7.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Peptidase_C1_2 PF03051.15 GAN07048.1 - 1.4e-165 551.3 0.4 1.6e-165 551.1 0.4 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 GAN07048.1 - 0.00018 21.7 0.2 0.12 12.4 0.2 2.5 2 0 0 2 2 2 2 Papain family cysteine protease MFS_1 PF07690.16 GAN07049.1 - 1.8e-51 175.1 29.8 2.2e-51 174.9 29.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN07049.1 - 3.9e-14 52.4 4.9 3.9e-14 52.4 4.9 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAN07049.1 - 1.3e-05 23.9 4.3 1.3e-05 23.9 4.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAN07050.1 - 2.8e-53 181.1 36.4 5.5e-53 180.1 35.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN07050.1 - 7.1e-14 51.5 5.0 7.1e-14 51.5 5.0 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAN07050.1 - 2.2e-05 23.1 2.6 2.2e-05 23.1 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5346 PF17281.2 GAN07050.1 - 0.029 14.4 0.9 8.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5346) MFS_3 PF05977.13 GAN07050.1 - 0.82 8.0 11.4 0.02 13.3 1.2 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 GAN07051.1 - 1.8e-49 168.5 35.2 1.8e-49 168.5 35.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN07051.1 - 1.9e-11 43.5 9.5 1.9e-11 43.5 9.5 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 GAN07051.1 - 2.2 6.6 7.2 0.18 10.1 2.1 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector TRM13 PF05206.14 GAN07052.1 - 1.1e-80 271.0 7.9 1.4e-80 270.6 7.9 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 GAN07052.1 - 6e-10 38.8 0.8 6e-10 38.8 0.8 2.1 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 GAN07052.1 - 0.00015 21.5 0.3 0.00015 21.5 0.3 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-TRAF PF02176.18 GAN07052.1 - 0.0064 17.2 1.4 0.058 14.1 1.4 2.7 1 1 0 1 1 1 1 TRAF-type zinc finger Ribosomal_S2 PF00318.20 GAN07053.1 - 1.5e-27 96.2 1.2 1.1e-13 51.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 GAN07053.1 - 1.3e-06 29.6 14.3 2.3e-06 28.9 14.3 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus PhoLip_ATPase_C PF16212.5 GAN07054.1 - 8.9e-67 225.4 37.3 8.9e-67 225.4 37.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAN07054.1 - 2.4e-22 78.4 0.8 2.4e-22 78.4 0.8 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAN07054.1 - 1.6e-11 44.2 0.0 9.6e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN07054.1 - 4.7e-11 43.4 0.0 3.4e-05 24.2 0.0 3.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAN07054.1 - 1.9e-06 27.5 0.2 1.9e-06 27.5 0.2 3.7 3 1 0 3 3 3 1 E1-E2 ATPase Pap_E4 PF02711.14 GAN07054.1 - 0.011 16.6 0.6 0.011 16.6 0.6 3.8 4 0 0 4 4 4 0 E4 protein Hydrolase_3 PF08282.12 GAN07054.1 - 0.014 15.1 0.1 0.014 15.1 0.1 3.1 5 0 0 5 5 5 0 haloacid dehalogenase-like hydrolase Ceramidase_alk PF04734.13 GAN07055.1 - 1.7e-199 663.7 0.0 2e-199 663.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GAN07055.1 - 6.4e-41 140.0 0.5 1e-40 139.4 0.5 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal RNA_pol_Rpb6 PF01192.22 GAN07056.1 - 7.7e-16 57.8 0.2 1.1e-15 57.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 GAN07056.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Malate_synthase PF01274.22 GAN07056.1 - 0.058 11.7 0.1 0.07 11.4 0.1 1.0 1 0 0 1 1 1 0 Malate synthase Nsp2a_N PF17896.1 GAN07057.1 - 0.082 12.1 1.9 0.091 11.9 1.9 1.1 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Sugar_tr PF00083.24 GAN07058.1 - 2.1e-37 129.1 24.1 3e-35 122.0 23.6 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN07058.1 - 2.6e-35 122.0 27.8 4.8e-35 121.1 27.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAN07058.1 - 0.0058 15.5 11.4 0.091 11.6 11.4 2.2 1 1 0 1 1 1 1 MFS_1 like family ATG22 PF11700.8 GAN07058.1 - 0.014 14.1 13.8 0.013 14.2 9.4 2.1 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Ta0938 PF11494.8 GAN07058.1 - 0.049 13.9 0.6 0.049 13.9 0.6 1.8 2 0 0 2 2 2 0 Ta0938 CoatB PF10389.9 GAN07058.1 - 2.7 7.9 5.0 1.7 8.6 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage coat protein B MBOAT_2 PF13813.6 GAN07059.1 - 2e-07 31.2 1.5 2e-07 31.2 1.5 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family FAR1 PF03101.15 GAN07060.1 - 0.00067 20.3 2.3 0.00067 20.3 2.3 2.7 2 1 0 2 2 2 1 FAR1 DNA-binding domain Shadoo PF14999.6 GAN07060.1 - 0.21 11.7 3.7 0.47 10.5 3.7 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Lipocalin_8 PF16585.5 GAN07061.1 - 0.24 11.8 3.6 0.53 10.7 3.0 1.8 1 1 1 2 2 2 0 Lipocalin-like domain O-antigen_lig PF13425.6 GAN07061.1 - 7.1 5.3 8.0 7.4 5.2 8.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ADH_N PF08240.12 GAN07062.1 - 5.5e-27 93.8 3.4 1e-26 92.9 3.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN07062.1 - 1.1e-10 41.5 0.0 1.2e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 GAN07062.1 - 0.03 14.1 0.0 0.066 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF1884 PF08967.10 GAN07062.1 - 0.044 14.0 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1884) AMP-binding PF00501.28 GAN07063.1 - 5.8e-104 348.0 0.1 9e-104 347.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NDK PF00334.19 GAN07064.1 - 4.3e-32 110.9 0.6 9.2e-32 109.9 0.0 1.9 2 0 0 2 2 2 1 Nucleoside diphosphate kinase HATPase_c PF02518.26 GAN07065.1 - 1.1e-28 100.0 0.0 1.2e-27 96.6 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAN07065.1 - 3.9e-24 85.0 2.3 6.4e-22 77.8 0.7 3.0 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAN07065.1 - 1.6e-16 60.0 1.3 4.8e-16 58.6 1.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAN07065.1 - 0.031 14.1 0.0 0.18 11.7 0.0 2.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Proteasome PF00227.26 GAN07066.1 - 3.8e-48 163.5 0.0 4.8e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAN07066.1 - 2.3e-13 49.5 0.1 4e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SWI-SNF_Ssr4 PF08549.10 GAN07067.1 - 3.2e-10 39.3 14.9 3.2e-10 39.3 14.9 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) zf-C2H2 PF00096.26 GAN07068.1 - 2.1e-06 27.8 21.5 0.00027 21.2 5.1 3.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN07068.1 - 5.6e-05 23.4 1.1 5.6e-05 23.4 1.1 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN07068.1 - 0.023 15.5 18.6 0.041 14.7 6.6 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 GAN07068.1 - 0.03 14.7 2.4 0.03 14.7 2.4 3.8 3 1 1 4 4 4 0 Zinc-finger of C2H2 type PQ-loop PF04193.14 GAN07069.1 - 4.4e-38 128.9 16.9 1.6e-19 69.4 3.2 3.1 3 0 0 3 3 3 2 PQ loop repeat DUF1689 PF07954.11 GAN07069.1 - 0.098 13.1 0.4 1.7 9.0 0.0 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1689) PI3K_1B_p101 PF10486.9 GAN07069.1 - 0.19 9.5 6.4 0.24 9.1 6.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1218 PF06749.12 GAN07069.1 - 0.21 12.1 1.5 0.36 11.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) zf_C2H2_ZHX PF18387.1 GAN07069.1 - 0.25 11.0 0.9 0.46 10.2 0.9 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain SPX PF03105.19 GAN07069.1 - 0.96 9.3 7.6 1.2 8.9 7.6 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GAN07069.1 - 4.6 5.7 8.8 6.4 5.2 8.8 1.1 1 0 0 1 1 1 0 Macoilin family Herpes_pp85 PF04637.12 GAN07069.1 - 6.1 5.1 6.2 7.8 4.8 6.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ECF_trnsprt PF12822.7 GAN07069.1 - 8.9 6.4 13.2 0.39 10.8 2.0 2.2 2 0 0 2 2 2 0 ECF transporter, substrate-specific component ACOX PF01756.19 GAN07070.1 - 7.5e-52 175.5 0.1 1.4e-51 174.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAN07070.1 - 2.2e-25 89.6 0.8 5e-25 88.5 0.8 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAN07070.1 - 1e-13 51.3 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAN07070.1 - 0.00018 21.8 0.4 0.00059 20.1 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain PRP21_like_P PF12230.8 GAN07071.1 - 7.5e-56 189.4 6.0 2.3e-55 187.8 6.0 1.8 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 GAN07071.1 - 9.5e-31 105.6 2.9 1.8e-17 63.0 0.2 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 GAN07071.1 - 1.9e-09 37.2 0.0 4.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 GAN07071.1 - 0.00013 21.4 0.1 0.00031 20.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Kelch_4 PF13418.6 GAN07072.1 - 2.9e-15 56.0 16.0 5e-05 23.2 0.2 6.4 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN07072.1 - 4.3e-12 45.9 11.9 4.5e-05 23.6 0.2 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 GAN07072.1 - 5.4e-10 39.0 7.2 0.12 12.4 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 GAN07072.1 - 3.7e-08 33.4 16.9 0.0041 17.4 2.5 4.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN07072.1 - 4.7e-08 32.7 1.7 1.1 9.4 0.0 5.7 6 0 0 6 6 6 3 Kelch motif VSP PF03302.13 GAN07072.1 - 0.00085 18.3 1.0 0.0012 17.8 1.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Kelch_1 PF01344.25 GAN07072.1 - 0.0011 18.5 9.0 0.043 13.4 0.2 5.1 5 0 0 5 5 5 1 Kelch motif Herpes_gE PF02480.16 GAN07072.1 - 0.018 13.8 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 GAN07072.1 - 0.048 13.1 2.0 0.099 12.1 2.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD99L2 PF12301.8 GAN07072.1 - 0.14 12.5 1.0 0.28 11.5 1.0 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 MbeD_MobD PF04899.12 GAN07074.1 - 0.0075 16.4 0.1 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 MbeD/MobD like DUF1843 PF08898.10 GAN07074.1 - 0.033 14.7 0.1 0.62 10.6 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) DUF2312 PF10073.9 GAN07074.1 - 0.078 12.6 0.1 7.4 6.3 0.0 3.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Leo1 PF04004.13 GAN07075.1 - 3.6e-45 153.8 0.3 3.6e-45 153.8 0.3 2.7 3 0 0 3 3 3 1 Leo1-like protein UPF0524 PF15823.5 GAN07075.1 - 0.039 13.4 0.0 0.039 13.4 0.0 2.8 2 1 1 3 3 3 0 UPF0524 of C3orf70 GATA PF00320.27 GAN07076.1 - 1.2e-27 95.2 21.7 6.7e-15 54.4 8.8 2.9 2 0 0 2 2 2 2 GATA zinc finger SET PF00856.28 GAN07076.1 - 2e-20 73.9 2.5 2.4e-19 70.3 1.5 2.9 2 1 0 2 2 2 1 SET domain AWS PF17907.1 GAN07076.1 - 1e-16 60.7 13.2 1e-16 60.7 13.2 2.7 3 0 0 3 3 3 1 AWS domain zf-Sec23_Sec24 PF04810.15 GAN07076.1 - 1.4 9.0 13.7 2.4 8.3 1.5 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Chs7 PF12271.8 GAN07078.1 - 5e-101 337.8 19.3 6.3e-101 337.5 19.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Usp PF00582.26 GAN07079.1 - 3.8e-26 92.3 0.1 4.9e-25 88.7 0.1 1.9 1 1 0 1 1 1 1 Universal stress protein family CorA PF01544.18 GAN07080.1 - 1.3e-08 34.5 2.1 2.7e-08 33.5 2.1 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Dynactin_p22 PF07426.11 GAN07080.1 - 0.0078 16.1 2.0 0.038 13.8 0.2 2.2 2 0 0 2 2 2 1 Dynactin subunit p22 FBPase PF00316.20 GAN07082.1 - 6e-74 247.6 0.1 7.9e-74 247.2 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Ntox30 PF15532.6 GAN07082.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 30 DDHD PF02862.17 GAN07083.1 - 5.8e-31 108.4 0.9 1.1e-30 107.5 0.9 1.4 1 0 0 1 1 1 1 DDHD domain Zn_clus PF00172.18 GAN07084.1 - 7.7e-09 35.5 7.9 1.3e-08 34.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 GAN07085.1 - 1.1e-58 197.4 0.3 1.3e-58 197.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN07085.1 - 1.3e-35 122.2 0.2 4.5e-35 120.5 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN07085.1 - 7.9e-15 54.7 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN07085.1 - 4.4e-06 26.2 0.0 5.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAN07085.1 - 1.2e-05 25.0 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN07085.1 - 1.7e-05 24.9 0.0 3.4e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAN07085.1 - 3.6e-05 24.2 0.1 5.1e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAN07085.1 - 0.0019 18.1 0.2 0.27 11.1 0.0 2.5 2 1 0 2 2 2 1 RsgA GTPase TniB PF05621.11 GAN07085.1 - 0.064 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein APC_basic PF05956.11 GAN07085.1 - 0.095 12.1 0.0 9 5.7 0.1 2.0 1 1 1 2 2 2 0 APC basic domain G-alpha PF00503.20 GAN07085.1 - 0.11 11.7 0.0 1.1 8.3 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 GAN07085.1 - 0.14 12.4 0.0 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain PBP PF01161.20 GAN07086.1 - 3.7e-21 75.8 0.1 4.7e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HLH PF00010.26 GAN07087.1 - 1.1e-12 47.7 0.4 1.1e-12 47.7 0.4 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HSL_N PF06350.12 GAN07087.1 - 0.054 12.5 1.2 0.096 11.6 1.2 1.3 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus DUF3439 PF11921.8 GAN07087.1 - 0.055 13.4 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) VTC PF09359.10 GAN07088.1 - 4.9e-84 282.0 0.1 8.3e-84 281.2 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 GAN07088.1 - 1.7e-12 48.0 15.7 1.4e-06 28.6 0.1 4.2 2 1 2 4 4 4 4 SPX domain DUF202 PF02656.15 GAN07088.1 - 3.6e-12 46.5 3.4 8.1e-12 45.4 3.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) JAB PF01398.21 GAN07089.1 - 5.4e-33 113.5 0.2 1.1e-32 112.5 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAN07089.1 - 5.9e-14 52.4 1.3 9.4e-14 51.8 0.7 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GAN07089.1 - 2.1e-06 27.5 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 GAN07089.1 - 0.076 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Mito_carr PF00153.27 GAN07090.1 - 7.8e-48 160.4 6.7 6.5e-16 58.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med6 PF04934.14 GAN07091.1 - 1.4e-42 144.7 0.3 1.9e-42 144.2 0.3 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Neur PF00064.18 GAN07091.1 - 0.05 12.4 0.1 0.075 11.8 0.1 1.3 1 0 0 1 1 1 0 Neuraminidase Pho88 PF10032.9 GAN07092.1 - 2.3e-53 180.2 0.0 2.5e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF1729 PF08354.10 GAN07093.1 - 8.3e-152 505.2 0.0 1.4e-151 504.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 GAN07093.1 - 8.9e-131 432.5 0.5 5.4e-65 218.7 0.0 2.8 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 GAN07093.1 - 1.7e-68 230.2 0.0 3.6e-68 229.2 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 GAN07093.1 - 6.9e-67 226.2 0.0 1.8e-66 224.8 0.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain FAS_meander PF17951.1 GAN07093.1 - 2.2e-44 150.8 0.2 5.9e-44 149.4 0.2 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 GAN07093.1 - 1.2e-30 105.6 0.3 3.8e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain SAT PF16073.5 GAN07093.1 - 2.3e-28 99.5 0.0 5.8e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 GAN07093.1 - 2.5e-27 95.5 0.1 6.5e-27 94.1 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta ketoacyl-synt PF00109.26 GAN07093.1 - 2.6e-20 73.1 0.1 7.6e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MaoC_dehydrat_N PF13452.6 GAN07093.1 - 1.5e-16 60.7 0.0 5.6e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase ACPS PF01648.20 GAN07093.1 - 3.1e-16 59.5 0.0 9.3e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 GAN07093.1 - 4.6e-10 39.5 0.0 1.3e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAN07093.1 - 0.011 15.2 0.0 0.039 13.4 0.0 2.0 1 0 0 1 1 1 0 short chain dehydrogenase TipAS PF07739.13 GAN07093.1 - 0.013 16.0 1.6 0.066 13.8 1.6 2.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Es2 PF09751.9 GAN07094.1 - 5e-66 224.2 16.6 5.5e-47 161.5 7.3 2.9 2 1 1 3 3 3 2 Nuclear protein Es2 DUF4330 PF14221.6 GAN07096.1 - 0.093 12.9 0.1 0.099 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) ADH_zinc_N PF00107.26 GAN07097.1 - 1.5e-24 86.4 0.0 2.8e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN07097.1 - 2.3e-19 70.8 0.0 5.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN07097.1 - 4.1e-10 39.5 0.4 9e-10 38.4 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAN07097.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase rve PF00665.26 GAN07099.1 - 1.3e-12 47.9 0.0 3.4e-12 46.6 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GAN07099.1 - 0.017 14.9 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain WRKY PF03106.15 GAN07100.1 - 6.1e-08 32.8 4.1 1.4e-07 31.6 4.1 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Tfb2 PF03849.14 GAN07103.1 - 5.4e-143 476.3 7.8 6.4e-143 476.0 7.8 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GAN07103.1 - 4.1e-27 94.4 0.0 9e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GAN07103.1 - 0.00035 20.7 0.0 0.00075 19.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mrr_N PF14338.6 GAN07103.1 - 0.054 13.6 0.1 4.7 7.4 0.0 3.0 2 1 1 3 3 3 0 Mrr N-terminal domain Ribosomal_L27e PF01777.18 GAN07104.1 - 8.3e-28 96.6 5.0 1.9e-27 95.4 5.0 1.6 1 0 0 1 1 1 1 Ribosomal L27e protein family Ribosomal_S2 PF00318.20 GAN07104.1 - 3.4e-24 85.3 0.3 5.3e-12 45.4 0.0 2.4 1 1 1 2 2 2 2 Ribosomal protein S2 KOW PF00467.29 GAN07104.1 - 0.00089 19.1 2.1 0.002 18.0 2.1 1.7 1 0 0 1 1 1 1 KOW motif DLL_N PF12413.8 GAN07104.1 - 0.0088 17.3 0.1 0.023 15.9 0.1 1.7 1 0 0 1 1 1 1 Homeobox protein distal-less-like N terminal GATA PF00320.27 GAN07106.1 - 3.3e-15 55.4 3.7 8.6e-15 54.1 3.7 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN07106.1 - 0.067 12.7 0.8 0.21 11.2 0.8 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding Lzipper-MIP1 PF14389.6 GAN07106.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Apocytochr_F_N PF16639.5 GAN07106.1 - 0.18 12.1 1.5 14 5.9 0.0 2.7 2 1 1 3 3 3 0 Apocytochrome F, N-terminal TFIIA PF03153.13 GAN07106.1 - 0.23 11.4 16.5 0.33 10.9 16.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DZR PF12773.7 GAN07106.1 - 0.78 9.8 4.5 9 6.4 0.8 3.1 2 1 1 3 3 3 0 Double zinc ribbon Auto_anti-p27 PF06677.12 GAN07106.1 - 2.3 8.5 4.2 0.5 10.6 0.5 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) XRCC4 PF06632.12 GAN07106.1 - 5.3 5.8 12.7 0.072 11.9 0.3 2.9 2 1 1 3 3 3 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 zf-RRN7 PF11781.8 GAN07106.1 - 9.2 6.1 7.7 0.22 11.3 0.7 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Asn_synthase PF00733.21 GAN07107.1 - 3.1e-96 323.2 0.5 1.1e-58 199.6 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GAN07107.1 - 1.5e-38 131.5 0.0 2.8e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAN07107.1 - 1.8e-31 109.1 0.0 4.1e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAN07107.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAN07107.1 - 0.007 15.5 0.1 0.018 14.2 0.0 1.9 2 1 0 2 2 2 1 NAD synthase QueC PF06508.13 GAN07107.1 - 0.081 12.4 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF2390 PF09523.10 GAN07109.1 - 0.011 16.0 1.2 0.017 15.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DUF2004 PF09406.10 GAN07109.1 - 0.13 12.6 2.0 6.8 7.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2004) Shugoshin_N PF07558.11 GAN07109.1 - 0.55 10.2 3.3 6.7 6.7 0.2 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Sec63 PF02889.16 GAN07110.1 - 2.3e-26 92.5 0.0 6.2e-26 91.1 0.0 1.6 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 GAN07110.1 - 4.7e-20 71.5 0.5 1.2e-19 70.1 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain RXT2_N PF08595.11 GAN07110.1 - 4 7.4 13.4 0.16 11.9 0.3 3.2 3 1 0 3 3 3 0 RXT2-like, N-terminal ArAE_2_N PF10337.9 GAN07111.1 - 1.6e-14 53.8 1.4 1.6e-14 53.8 1.4 3.7 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAN07111.1 - 7.4e-14 52.0 10.0 7.4e-14 52.0 10.0 2.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 GAN07111.1 - 8.9e-13 47.9 4.2 8.9e-13 47.9 4.2 4.1 4 0 0 4 4 4 2 Aluminium activated malate transporter HLH PF00010.26 GAN07111.1 - 2.2e-12 46.8 1.6 6.4e-12 45.3 1.6 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ArAE_2 PF10334.9 GAN07111.1 - 3.3e-09 36.9 2.7 5.7e-09 36.1 0.9 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 GAN07111.1 - 7.7e-05 21.4 7.0 7.7e-05 21.4 7.0 3.1 4 0 0 4 4 4 1 Fusaric acid resistance protein family DivIC PF04977.15 GAN07111.1 - 0.011 15.5 4.2 0.63 9.9 0.7 3.9 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.18 GAN07111.1 - 0.19 12.0 1.8 0.79 10.0 1.8 2.1 1 0 0 1 1 1 0 Homeobox associated leucine zipper YabA PF06156.13 GAN07111.1 - 8 7.2 10.3 0.27 11.9 1.2 3.3 3 0 0 3 3 3 0 Initiation control protein YabA Cg6151-P PF10233.9 GAN07112.1 - 8.8e-29 100.1 16.4 1e-28 99.9 16.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4149 PF13664.6 GAN07112.1 - 0.065 13.5 1.4 0.065 13.5 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) ABC2_membrane_5 PF13346.6 GAN07112.1 - 0.14 11.7 16.1 0.19 11.3 16.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2798 PF11391.8 GAN07112.1 - 4.3 7.5 13.4 0.13 12.3 5.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2798) Tropomyosin_1 PF12718.7 GAN07113.1 - 4e-14 53.0 21.4 1.8e-10 41.1 8.5 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 GAN07113.1 - 2.1e-05 24.0 21.0 0.00066 19.1 7.1 2.1 2 0 0 2 2 2 2 Tropomyosin Tup_N PF08581.10 GAN07113.1 - 0.0014 18.9 6.2 0.0014 18.9 6.2 2.4 2 1 0 2 2 2 1 Tup N-terminal FlaC_arch PF05377.11 GAN07113.1 - 0.0026 18.1 13.4 0.077 13.4 4.4 3.6 2 2 0 3 3 3 1 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 GAN07113.1 - 0.0027 18.1 12.2 0.13 12.7 0.1 3.2 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) MscS_porin PF12795.7 GAN07113.1 - 0.0056 16.3 11.7 0.016 14.8 5.3 2.1 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Spc7 PF08317.11 GAN07113.1 - 0.0059 15.5 21.8 0.047 12.6 14.4 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GAN07113.1 - 0.0083 16.2 22.6 0.051 13.6 15.9 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein KGK PF08872.10 GAN07113.1 - 0.011 16.3 2.7 0.019 15.5 2.7 1.6 1 1 0 1 1 1 0 KGK domain DUF641 PF04859.12 GAN07113.1 - 0.014 15.7 5.6 0.014 15.7 5.6 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 GAN07113.1 - 0.014 15.9 27.3 3.2 8.3 27.0 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 GAN07113.1 - 0.023 14.0 15.0 0.058 12.7 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) INPP5B_PH PF16776.5 GAN07113.1 - 0.032 14.0 0.6 0.059 13.1 0.3 1.6 1 1 1 2 2 2 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain DUF1664 PF07889.12 GAN07113.1 - 0.04 13.9 10.4 0.1 12.7 4.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 GAN07113.1 - 0.045 14.1 19.4 0.33 11.3 7.2 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 GAN07113.1 - 0.048 13.7 25.5 0.9 9.6 8.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dad4 PF08650.10 GAN07113.1 - 0.054 13.5 7.1 0.78 9.8 0.3 3.1 2 1 1 3 3 3 0 DASH complex subunit Dad4 ADIP PF11559.8 GAN07113.1 - 0.063 13.4 17.5 0.48 10.5 8.9 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 GAN07113.1 - 0.065 13.5 19.7 0.045 14.0 6.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2730 PF10805.8 GAN07113.1 - 0.082 13.0 12.0 0.19 11.9 6.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) HCMV_UL139 PF12507.8 GAN07113.1 - 0.083 13.3 10.0 5.9 7.3 10.0 2.2 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein Tli4_N PF18443.1 GAN07113.1 - 0.1 13.0 3.4 0.24 11.7 3.0 1.9 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain HMMR_N PF15905.5 GAN07113.1 - 0.1 12.0 22.1 5.4 6.4 22.1 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 GAN07113.1 - 0.13 12.0 17.7 1 9.1 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.21 GAN07113.1 - 0.14 11.8 19.3 0.21 11.2 7.2 2.0 1 1 1 2 2 2 0 Intermediate filament protein NBP1 PF08537.10 GAN07113.1 - 0.16 11.3 17.0 0.056 12.9 5.1 2.0 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Occludin_ELL PF07303.13 GAN07113.1 - 0.25 12.1 13.4 2.2 9.1 1.3 2.3 2 0 0 2 2 2 0 Occludin homology domain Fez1 PF06818.15 GAN07113.1 - 0.29 11.6 18.3 0.67 10.4 17.4 1.8 1 1 0 1 1 1 0 Fez1 ERM PF00769.19 GAN07113.1 - 0.34 10.7 28.2 0.042 13.7 8.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family YscO PF07321.12 GAN07113.1 - 0.38 10.7 20.8 0.05 13.5 5.0 2.5 2 1 0 2 2 2 0 Type III secretion protein YscO ATG16 PF08614.11 GAN07113.1 - 0.4 10.9 21.4 0.41 10.9 4.8 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) SKA1 PF07160.12 GAN07113.1 - 0.41 10.5 12.8 1.4 8.7 2.2 2.4 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 HemX PF04375.14 GAN07113.1 - 0.42 9.9 15.3 1.1 8.5 0.9 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fib_alpha PF08702.10 GAN07113.1 - 0.44 10.7 12.6 2.1 8.5 5.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HalX PF08663.10 GAN07113.1 - 0.44 10.9 18.7 2.9 8.3 6.7 3.2 2 1 0 2 2 2 0 HalX domain EzrA PF06160.12 GAN07113.1 - 0.45 8.6 19.3 0.61 8.2 5.6 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Laminin_II PF06009.12 GAN07113.1 - 0.46 10.5 12.1 2.6 8.1 0.8 2.3 1 1 1 2 2 2 0 Laminin Domain II FPP PF05911.11 GAN07113.1 - 0.46 8.6 20.1 0.85 7.7 20.1 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil FliJ PF02050.16 GAN07113.1 - 0.53 10.5 17.2 1.1 9.5 2.7 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein DUF3584 PF12128.8 GAN07113.1 - 0.53 7.7 17.4 0.56 7.6 17.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 GAN07113.1 - 0.55 9.8 10.0 0.65 9.5 10.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BST2 PF16716.5 GAN07113.1 - 0.56 10.8 18.0 1.4 9.5 2.4 2.5 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 ZapB PF06005.12 GAN07113.1 - 0.63 10.5 20.4 2.7 8.5 6.3 2.6 2 1 1 3 3 3 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 GAN07113.1 - 0.65 10.2 21.8 3.5 7.9 15.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2802 PF10975.8 GAN07113.1 - 0.66 10.1 12.6 2.5 8.3 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) SHE3 PF17078.5 GAN07113.1 - 0.69 9.6 17.1 1.4 8.5 17.1 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4164 PF13747.6 GAN07113.1 - 0.75 10.1 14.5 0.32 11.3 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DHR10 PF18595.1 GAN07113.1 - 0.86 9.7 24.0 1.9 8.6 6.9 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain BRI3BP PF14965.6 GAN07113.1 - 0.89 9.0 3.2 9.8 5.6 0.1 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 HIP1_clath_bdg PF16515.5 GAN07113.1 - 0.9 10.2 18.3 1.2 9.8 7.4 2.4 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fmp27_WPPW PF10359.9 GAN07113.1 - 0.94 8.3 17.2 0.48 9.2 2.8 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain MCC-bdg_PDZ PF10506.9 GAN07113.1 - 1.3 9.1 14.2 1.9 8.6 3.3 2.8 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome She9_MDM33 PF05546.11 GAN07113.1 - 1.3 8.8 13.5 0.25 11.1 1.7 2.5 1 1 2 3 3 3 0 She9 / Mdm33 family ABC_tran_CTD PF16326.5 GAN07113.1 - 1.5 9.1 25.4 0.88 9.9 9.6 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain Lectin_N PF03954.14 GAN07113.1 - 1.8 8.3 9.3 0.52 10.1 3.6 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain SLIDE PF09111.10 GAN07113.1 - 1.8 8.6 10.5 0.17 11.9 1.3 2.4 1 1 0 2 2 2 0 SLIDE Rho_Binding PF08912.11 GAN07113.1 - 2.3 9.1 23.8 0.46 11.3 2.5 3.0 2 1 1 3 3 3 0 Rho Binding Csm1_N PF18504.1 GAN07113.1 - 2.4 8.6 21.0 3.1 8.2 2.7 3.7 2 2 1 3 3 3 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 GAN07113.1 - 3.1 7.9 22.8 3.1 7.9 6.1 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 GAN07113.1 - 3.2 8.2 24.9 1.5 9.2 9.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF812 PF05667.11 GAN07113.1 - 3.5 6.4 22.7 0.33 9.8 9.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) PRKG1_interact PF15898.5 GAN07113.1 - 3.9 8.4 21.3 8.4 7.4 0.8 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 GAN07113.1 - 4.1 6.7 26.0 4.2e+02 0.1 26.2 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4795 PF16043.5 GAN07113.1 - 4.1 6.9 19.9 7.9 6.0 19.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) V_ATPase_I PF01496.19 GAN07113.1 - 4.7 5.0 14.1 11 3.7 14.2 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 GAN07113.1 - 4.7 7.5 23.4 20 5.5 21.3 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 GAN07113.1 - 5.4 7.8 8.8 18 6.1 0.7 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Swi5 PF07061.11 GAN07113.1 - 5.6 7.1 20.6 3.3 7.9 2.9 3.3 2 1 1 3 3 3 0 Swi5 DUF4407 PF14362.6 GAN07113.1 - 5.8 6.2 12.7 15 4.8 12.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 GAN07113.1 - 6.4 6.6 22.3 1.4 8.7 3.5 3.2 2 1 1 3 3 3 0 Septum formation initiator FmiP_Thoc5 PF09766.9 GAN07113.1 - 6.4 6.0 16.9 0.67 9.2 6.0 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 EMP24_GP25L PF01105.24 GAN07113.1 - 7.3 6.5 12.5 6.7 6.6 4.6 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF16 PF01519.16 GAN07113.1 - 7.6 7.1 15.4 4.4 7.8 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 FapA PF03961.13 GAN07113.1 - 7.8 5.0 18.2 5.7 5.4 6.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4094 PF13334.6 GAN07113.1 - 8.1 6.9 11.3 7.5 7.0 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF202 PF02656.15 GAN07114.1 - 2.1e-21 76.1 0.5 2.1e-21 76.1 0.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF4097 PF13349.6 GAN07115.1 - 3.3e-07 29.9 0.3 4e-07 29.6 0.3 1.0 1 0 0 1 1 1 1 Putative adhesin Fil_haemagg_2 PF13332.6 GAN07115.1 - 0.0016 18.6 5.1 0.16 12.0 0.5 2.0 1 1 0 1 1 1 1 Hemagglutinin repeat DUF3552 PF12072.8 GAN07115.1 - 0.0045 16.4 0.0 0.31 10.4 0.0 1.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) HALZ PF02183.18 GAN07115.1 - 0.049 13.9 0.7 1.8 8.8 0.3 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Phage_spike PF18715.1 GAN07115.1 - 0.067 13.3 10.8 77 3.5 10.8 3.0 1 1 0 1 1 1 0 Phage spike trimer DUF4469 PF14734.6 GAN07115.1 - 7.6 6.8 9.5 21 5.3 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold 6PF2K PF01591.18 GAN07117.1 - 1e-64 217.9 0.0 2.4e-64 216.7 0.0 1.6 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAN07117.1 - 8.3e-21 74.6 0.0 2.7e-20 72.9 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) W2 PF02020.18 GAN07117.1 - 0.0036 17.4 0.0 0.014 15.5 0.0 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF29 PF01724.16 GAN07117.1 - 0.045 14.0 2.0 4.1 7.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF29 AAA_33 PF13671.6 GAN07117.1 - 0.071 13.3 0.0 1.1 9.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain C2 PF00168.30 GAN07119.1 - 7.2e-16 58.4 0.0 1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 GAN07120.1 - 3.4e-60 203.7 0.0 4.5e-39 134.4 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07120.1 - 5.2e-32 111.1 0.0 3.4e-23 82.2 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Response_reg PF00072.24 GAN07120.1 - 4e-13 49.5 0.4 1.2e-12 48.0 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.6 GAN07120.1 - 0.0011 18.4 0.0 0.026 13.9 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAN07120.1 - 0.0024 17.8 0.1 0.0071 16.3 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN07120.1 - 0.0094 14.9 3.0 0.014 14.3 0.1 2.6 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GAN07120.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 GAN07120.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF465 PF04325.13 GAN07120.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF465) WD40 PF00400.32 GAN07121.1 - 3.6e-30 103.6 11.8 1.7e-07 31.8 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07121.1 - 5.1e-08 33.1 0.2 0.0067 16.7 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN07121.1 - 0.00066 19.1 0.0 0.031 13.6 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 GAN07121.1 - 0.024 13.4 0.5 1.7 7.3 0.1 2.7 2 1 1 3 3 3 0 Nup133 N terminal like WSN PF02206.18 GAN07121.1 - 0.1 12.5 0.3 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function WD40 PF00400.32 GAN07122.1 - 4e-15 55.9 6.2 1.8e-05 25.4 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07122.1 - 6.5e-10 39.2 0.2 0.0033 17.7 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN07122.1 - 2.6e-06 27.0 0.0 0.082 12.2 0.0 2.4 2 1 0 2 2 2 2 WD40-like domain Kelch_1 PF01344.25 GAN07122.1 - 0.12 12.0 0.1 0.29 10.7 0.1 1.7 1 1 0 1 1 1 0 Kelch motif Ammonium_transp PF00909.21 GAN07123.1 - 7.1e-122 406.9 27.7 8.1e-122 406.7 27.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_3_1 PF05106.12 GAN07123.1 - 7.2 7.1 12.4 0.1 13.1 1.5 2.9 3 1 0 3 3 3 0 Phage holin family (Lysis protein S) START PF01852.19 GAN07124.1 - 9.9e-13 48.0 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 START domain Galactosyl_T PF01762.21 GAN07125.1 - 3.6e-26 92.2 0.0 5.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 GAN07125.1 - 9.2e-14 51.7 21.1 8.2e-13 48.7 21.1 2.1 1 1 0 1 1 1 1 N-glycosylation protein Herpes_U26 PF07402.11 GAN07125.1 - 0.0057 16.3 0.7 0.0057 16.3 0.7 1.6 2 0 0 2 2 2 1 Human herpesvirus U26 protein FAD_binding_2 PF00890.24 GAN07126.1 - 5.6e-85 285.9 0.6 9.7e-84 281.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 GAN07126.1 - 1.8e-24 85.6 0.0 2e-23 82.3 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 GAN07126.1 - 3.8e-14 53.1 0.0 6.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAN07126.1 - 3e-08 33.4 0.1 4.9e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN07126.1 - 3.6e-08 33.5 0.2 1.8e-07 31.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN07126.1 - 2.9e-05 23.4 0.7 0.00014 21.2 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN07126.1 - 7.2e-05 21.7 3.1 0.0005 18.9 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAN07126.1 - 0.0016 17.7 1.3 0.03 13.6 0.0 2.8 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 GAN07126.1 - 0.0029 16.8 0.9 0.009 15.1 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAN07126.1 - 0.0061 15.9 0.1 0.0096 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAN07126.1 - 0.023 14.0 0.2 0.061 12.6 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAN07126.1 - 0.026 13.8 0.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAN07126.1 - 0.1 11.9 0.0 0.67 9.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 GAN07126.1 - 0.15 11.1 0.4 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAN07126.1 - 0.17 12.4 0.5 1.9 9.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_60s PF00428.19 GAN07126.1 - 1 10.0 5.3 0.81 10.3 2.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Kinesin PF00225.23 GAN07127.1 - 3.1e-97 325.5 1.3 3.4e-97 325.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 GAN07127.1 - 1.8e-47 161.9 3.0 1.8e-47 161.9 3.0 3.1 3 0 0 3 3 3 1 Kinesin-associated DUF3694 PF12473.8 GAN07127.1 - 2.7e-43 148.3 0.2 2.7e-43 148.3 0.2 2.1 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 GAN07127.1 - 2e-16 60.3 0.1 1.8e-15 57.2 0.1 2.5 1 1 0 1 1 1 1 Microtubule binding PH PF00169.29 GAN07127.1 - 3.6e-09 37.1 0.2 1.2e-08 35.4 0.2 1.9 1 0 0 1 1 1 1 PH domain FHA PF00498.26 GAN07127.1 - 3.8e-06 27.2 0.0 2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 GAN07127.1 - 1.1e-05 25.8 0.8 0.00023 21.5 0.1 3.0 2 0 0 2 2 2 1 Kinesin protein 1B Sds3 PF08598.11 GAN07127.1 - 0.0016 18.5 3.3 0.0018 18.3 0.1 2.5 2 0 0 2 2 2 1 Sds3-like PH_9 PF15410.6 GAN07127.1 - 0.0076 16.6 0.2 0.028 14.8 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain TBD PF12845.7 GAN07127.1 - 0.013 15.4 1.6 0.13 12.2 0.1 3.0 2 0 0 2 2 2 0 TBD domain Cortex-I_coil PF09304.10 GAN07127.1 - 0.19 12.0 5.4 1.1 9.6 3.5 3.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil Acyltransferase PF01553.21 GAN07128.1 - 2.2e-12 46.7 0.0 6.4e-11 42.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Ccdc124 PF06244.12 GAN07129.1 - 2.4e-27 96.0 24.0 2.4e-27 96.0 24.0 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Dsh_C PF12316.8 GAN07129.1 - 7.6 6.9 8.3 13 6.1 8.3 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF3666 PF12408.8 GAN07130.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase BLOC1_2 PF10046.9 GAN07130.1 - 1.4 9.2 7.4 0.25 11.7 1.5 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 GAN07130.1 - 5.2 6.3 9.9 9 5.5 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 GAN07131.1 - 7.5e-67 221.3 3.2 1.4e-22 79.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.7 GAN07132.1 - 1.4e-21 78.1 0.0 1.9e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAN07132.1 - 5.4e-14 52.5 0.3 7.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN07132.1 - 4.3e-10 39.3 0.1 7e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAN07132.1 - 2.1e-05 23.5 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 GAN07132.1 - 4.4e-05 23.7 0.0 8.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 GAN07132.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 GAN07132.1 - 0.00052 19.7 0.2 0.00088 18.9 0.2 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAN07132.1 - 0.0015 18.3 0.6 0.0029 17.4 0.4 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAN07132.1 - 0.0033 17.0 0.4 0.0051 16.3 0.4 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PAF-AH_p_II PF03403.13 GAN07132.1 - 0.0055 15.3 0.2 0.056 11.9 0.2 2.1 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Ser_hydrolase PF06821.13 GAN07132.1 - 0.0071 16.2 0.1 0.02 14.8 0.1 1.8 1 1 0 1 1 1 1 Serine hydrolase Methyltransf_32 PF13679.6 GAN07132.1 - 0.023 14.7 1.1 0.044 13.8 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain Cutinase PF01083.22 GAN07132.1 - 0.033 14.2 0.1 0.049 13.6 0.1 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 GAN07132.1 - 0.046 13.6 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DLH PF01738.18 GAN07132.1 - 0.059 12.9 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF900 PF05990.12 GAN07132.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 GAN07132.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.11 GAN07132.1 - 0.15 12.0 0.1 25 4.7 0.0 2.6 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal SHNi-TPR PF10516.9 GAN07134.1 - 4.6e-13 48.4 5.3 1.1e-12 47.2 0.4 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 GAN07134.1 - 9.9e-10 38.6 0.6 3.3e-09 36.9 0.6 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN07134.1 - 1.1e-05 25.2 8.0 0.0012 18.8 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAN07134.1 - 4.3e-05 23.2 4.4 0.00065 19.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAN07134.1 - 7.3e-05 22.7 4.7 0.044 14.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAN07134.1 - 0.00037 20.3 0.5 0.0061 16.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN07134.1 - 0.14 11.8 11.6 0.098 12.4 1.7 4.9 3 2 3 6 6 6 0 TPR repeat TPR_17 PF13431.6 GAN07134.1 - 0.19 12.2 4.7 12 6.6 0.3 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat FAM76 PF16046.5 GAN07134.1 - 0.94 8.8 7.2 0.064 12.6 1.0 2.0 2 0 0 2 2 2 0 FAM76 protein MIT PF04212.18 GAN07134.1 - 4.2 7.5 9.5 33 4.7 4.7 4.1 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain Flavokinase PF01687.17 GAN07135.1 - 1.9e-33 115.1 0.0 4.6e-33 113.8 0.0 1.6 1 1 0 1 1 1 1 Riboflavin kinase CBAH PF02275.18 GAN07135.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Peptidase_C9 PF01707.16 GAN07135.1 - 0.04 13.5 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C9 Glyco_hydro_31 PF01055.26 GAN07136.1 - 1.4e-53 182.7 0.9 1.9e-53 182.2 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAN07136.1 - 5.5e-05 23.4 0.2 0.00032 21.0 0.2 2.2 1 1 0 1 1 1 1 Galactose mutarotase-like Gpr1_Fun34_YaaH PF01184.19 GAN07137.1 - 6.4e-27 94.5 25.4 7.7e-27 94.3 25.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Vac_ImportDeg PF09783.9 GAN07138.1 - 2.3e-58 196.6 1.2 2.9e-58 196.3 1.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein G_glu_transpept PF01019.21 GAN07139.1 - 2.1e-166 554.7 0.0 2.4e-166 554.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TAF4 PF05236.14 GAN07140.1 - 2.6e-24 86.5 13.0 7.5e-23 81.6 10.7 4.0 2 1 2 4 4 4 2 Transcription initiation factor TFIID component TAF4 family F-box-like PF12937.7 GAN07141.1 - 9.6e-09 35.0 0.3 1.6e-07 31.1 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN07141.1 - 0.0024 17.7 0.0 0.017 15.0 0.0 2.5 1 0 0 1 1 1 1 F-box domain LIDHydrolase PF10230.9 GAN07142.1 - 1.6e-68 231.2 0.2 1.9e-68 230.9 0.2 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 GAN07142.1 - 2e-07 30.5 0.1 2.1e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN07142.1 - 1.3e-06 28.3 0.1 3.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN07142.1 - 0.00078 20.1 0.0 0.00096 19.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAN07142.1 - 0.0029 17.4 0.1 0.0048 16.6 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.12 GAN07142.1 - 0.043 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2920 PF11144.8 GAN07142.1 - 0.054 12.7 2.4 2.6 7.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2920) Lipase_3 PF01764.25 GAN07142.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DnaT PF17948.1 GAN07142.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 DnaT DNA-binding domain Pkinase PF00069.25 GAN07143.1 - 1.1e-26 93.8 0.0 1.7e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07143.1 - 2.4e-24 86.1 0.0 3.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN07143.1 - 0.074 13.0 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.29 GAN07144.1 - 8.6e-45 152.6 0.0 1.4e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN07144.1 - 6.3e-31 107.0 0.0 1.8e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RanBP PF00641.18 GAN07144.1 - 3e-29 100.0 20.8 3e-12 45.6 2.3 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others ResIII PF04851.15 GAN07144.1 - 0.0013 18.8 0.0 0.0043 17.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAN07144.1 - 0.13 11.0 0.0 1 8.0 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Rubredoxin PF00301.20 GAN07144.1 - 1 9.4 18.0 0.48 10.5 0.2 4.0 4 1 0 4 4 4 0 Rubredoxin zf-ribbon_3 PF13248.6 GAN07144.1 - 1.5 8.3 6.8 13 5.4 0.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 GAN07144.1 - 4.2 7.5 12.0 4.3 7.5 0.2 3.1 2 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 GAN07144.1 - 6.7 6.8 15.9 21 5.3 8.3 2.7 1 1 1 2 2 2 0 Double zinc ribbon PHD_4 PF16866.5 GAN07144.1 - 7.3 6.8 7.8 5.5 7.2 0.1 3.2 3 0 0 3 3 3 0 PHD-finger Ribosomal_L4 PF00573.22 GAN07145.1 - 2.5e-69 232.8 0.0 3.4e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PIG-S PF10510.9 GAN07146.1 - 0.063 12.1 3.6 0.072 11.9 3.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein MFS_5 PF05631.14 GAN07147.1 - 6.3e-67 226.0 10.0 8.5e-67 225.5 10.0 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAN07147.1 - 2.9e-18 65.9 43.5 3.6e-17 62.3 29.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Caps_synth_CapC PF14102.6 GAN07147.1 - 0.51 10.8 14.3 0.19 12.1 3.2 3.5 3 2 0 3 3 3 0 Capsule biosynthesis CapC MMtag PF10159.9 GAN07148.1 - 5.9e-34 116.2 2.1 5.9e-34 116.2 2.1 3.3 3 1 0 3 3 3 1 Multiple myeloma tumor-associated Transket_pyr PF02779.24 GAN07149.1 - 7.8e-46 156.0 0.1 1.5e-45 155.1 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAN07149.1 - 2.8e-36 124.1 0.1 1e-35 122.3 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GAN07149.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II F-box-like PF12937.7 GAN07150.1 - 8.9e-05 22.3 0.1 0.00027 20.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like OPT PF03169.15 GAN07151.1 - 2.7e-159 531.7 44.8 3.1e-159 531.5 44.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ACOX PF01756.19 GAN07152.1 - 4.2e-34 117.7 0.2 1.2e-33 116.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAN07152.1 - 1.2e-16 61.4 0.7 3.1e-16 60.1 0.7 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAN07152.1 - 1.2e-15 57.5 0.3 2.2e-15 56.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAN07152.1 - 0.026 14.7 1.0 0.19 12.0 0.1 2.7 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Spidroin_N PF16763.5 GAN07152.1 - 0.12 12.4 0.0 0.55 10.3 0.0 2.1 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Zds_C PF08632.10 GAN07153.1 - 4.4e-24 84.0 1.8 8.4e-24 83.1 1.8 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF755 PF05501.11 GAN07153.1 - 0.024 14.9 3.3 0.024 14.9 3.3 6.5 5 1 0 6 6 6 0 Domain of unknown function (DUF755) SpoU_methylase PF00588.19 GAN07154.1 - 4.5e-24 85.2 0.0 2.1e-23 83.1 0.0 2.2 2 0 0 2 2 2 1 SpoU rRNA Methylase family XPG_I PF00867.18 GAN07154.1 - 2.7e-18 66.1 0.0 1.1e-17 64.2 0.0 2.1 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAN07154.1 - 3.5e-06 27.4 0.0 1.1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain Robl_LC7 PF03259.17 GAN07155.1 - 2.6e-21 75.2 0.1 2.9e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 GAN07155.1 - 0.00073 19.4 0.2 0.00093 19.1 0.2 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 MRFAP1 PF15155.6 GAN07155.1 - 0.099 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 zf-C2H2 PF00096.26 GAN07156.1 - 2.8e-38 128.2 64.2 2.3e-05 24.6 0.6 10.2 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN07156.1 - 1.1e-22 78.8 63.6 0.0039 17.9 0.6 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN07156.1 - 4.8e-16 58.4 68.5 0.0043 17.4 0.4 11.7 11 1 0 11 11 11 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAN07156.1 - 9.7e-12 44.6 39.5 0.012 15.6 0.1 8.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN07156.1 - 1.2e-08 35.0 47.9 0.0023 18.2 0.2 8.7 9 0 0 9 9 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN07156.1 - 3.3e-07 30.5 45.7 0.07 13.5 0.3 8.6 9 0 0 9 9 8 4 Zinc-finger of C2H2 type FOXP-CC PF16159.5 GAN07156.1 - 6.6e-06 26.7 33.8 0.0015 19.2 0.4 8.5 4 2 4 8 8 8 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 GAN07156.1 - 4.6e-05 23.6 27.8 0.0027 18.0 8.6 4.5 1 1 4 5 5 5 3 C2H2-type zinc ribbon GAGA PF09237.11 GAN07156.1 - 9.7e-05 22.1 6.3 0.00066 19.4 0.2 4.2 3 1 1 4 4 4 1 GAGA factor zf-C2H2_3rep PF18868.1 GAN07156.1 - 0.00016 22.3 27.8 0.015 16.0 6.4 6.0 2 2 4 6 6 6 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_aberr PF17017.5 GAN07156.1 - 0.00018 21.7 28.4 0.0015 18.7 0.4 4.9 2 1 2 4 4 4 2 Aberrant zinc-finger PyrI_C PF02748.15 GAN07156.1 - 0.0012 18.7 17.8 0.05 13.5 0.7 5.2 5 1 0 5 5 5 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_12 PF18658.1 GAN07156.1 - 0.018 14.6 12.7 1.2 8.8 0.5 4.9 2 2 2 4 4 4 0 Zinc-finger C2H2-type Zf_RING PF16744.5 GAN07156.1 - 0.046 13.8 11.5 4 7.6 0.1 4.6 3 1 1 4 4 4 0 KIAA1045 RING finger zf_UBZ PF18439.1 GAN07156.1 - 0.37 10.4 15.5 3.3 7.4 0.1 5.8 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 GAN07156.1 - 0.55 10.0 0.0 0.55 10.0 0.0 5.9 8 0 0 8 8 8 0 zinc-finger C2H2-type C2-set_2 PF08205.12 GAN07156.1 - 0.59 10.2 4.6 1.4 9.0 0.7 2.9 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain zf_C2H2_ZHX PF18387.1 GAN07156.1 - 2.2 8.0 28.6 1.6 8.4 0.7 5.7 4 1 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain BolA PF01722.18 GAN07156.1 - 4.5 7.6 11.3 1.6 9.1 0.2 3.2 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_2 PF12756.7 GAN07156.1 - 5.7 7.3 45.6 1.5 9.2 0.3 7.1 1 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) PRiA4_ORF3 PF07929.11 GAN07157.1 - 0.026 14.2 6.2 0.014 15.1 2.1 2.3 1 1 1 2 2 2 0 Plasmid pRiA4b ORF-3-like protein VEK-30 PF12107.8 GAN07157.1 - 2.5 8.1 6.3 2.3 8.3 0.9 2.8 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway DUF4112 PF13430.6 GAN07158.1 - 1.1e-23 83.5 0.1 2.2e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DNA_pol3_delta PF06144.13 GAN07158.1 - 0.061 13.1 0.2 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Phasin PF05597.11 GAN07158.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DASH_Dad1 PF08649.10 GAN07159.1 - 1.3e-05 25.3 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 DASH complex subunit Dad1 PMEI PF04043.15 GAN07159.1 - 0.038 14.3 0.3 0.046 14.1 0.3 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor SpoIIE PF07228.12 GAN07160.1 - 3.1e-15 56.6 0.0 5.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAN07160.1 - 6.1e-08 32.6 0.1 2.5e-07 30.5 0.0 1.9 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 GAN07160.1 - 9.6e-05 22.1 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C MFS_1 PF07690.16 GAN07161.1 - 1.6e-40 139.2 30.4 1.6e-40 139.2 30.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAN07161.1 - 4.8e-05 22.8 3.4 4.8e-05 22.8 3.4 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4329 PF14220.6 GAN07161.1 - 0.044 13.8 2.4 0.072 13.1 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) Dicty_REP PF05086.12 GAN07161.1 - 0.67 7.9 5.4 0.87 7.5 5.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4231 PF14015.6 GAN07161.1 - 0.68 10.4 3.7 3.8 8.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1772 PF08592.11 GAN07161.1 - 8.5 6.7 13.2 31 4.9 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 GAN07162.1 - 6.8e-33 114.0 27.4 6.8e-33 114.0 27.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbN PF02468.15 GAN07162.1 - 0.93 9.4 4.2 5.4 6.9 0.6 3.0 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) MgtE PF01769.16 GAN07163.1 - 3.8e-44 150.1 30.0 6.2e-25 88.0 5.9 3.3 3 0 0 3 3 3 2 Divalent cation transporter Phage_holin_3_3 PF16083.5 GAN07163.1 - 0.059 13.5 0.8 0.059 13.5 0.8 3.9 4 1 1 5 5 5 0 LydA holin phage, holin superfamily III DUF5079 PF16882.5 GAN07163.1 - 0.38 10.6 12.4 0.023 14.6 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) ECH_2 PF16113.5 GAN07164.1 - 4.3e-102 342.0 0.0 9.1e-102 341.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAN07164.1 - 7.8e-24 84.4 0.1 3.2e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Mt_ATP-synt_B PF05405.14 GAN07164.1 - 0.19 11.3 0.5 0.44 10.2 0.4 1.7 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-CSL PF05207.13 GAN07165.1 - 3e-18 65.3 2.1 4.9e-18 64.6 2.1 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 GAN07165.1 - 5.6e-18 64.8 0.9 8.5e-18 64.2 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain RF-1 PF00472.20 GAN07166.1 - 6.6e-22 77.6 0.5 8.9e-22 77.2 0.5 1.2 1 0 0 1 1 1 1 RF-1 domain CCDC106 PF15794.5 GAN07166.1 - 0.065 12.9 1.9 0.082 12.6 1.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4973 PF16343.5 GAN07168.1 - 0.12 12.4 0.2 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) Bclx_interact PF08945.10 GAN07168.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain CTP_transf_like PF01467.26 GAN07169.1 - 5.4e-30 104.5 0.0 9.8e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 GAN07169.1 - 0.016 15.4 0.0 0.061 13.5 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5639) DUF5499 PF17603.2 GAN07169.1 - 0.068 13.8 0.1 0.2 12.3 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5499) CybS PF05328.12 GAN07170.1 - 2.7e-33 114.5 0.3 3.1e-33 114.3 0.3 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DASH_Dad1 PF08649.10 GAN07172.1 - 7.8e-11 42.0 0.3 1.4e-10 41.2 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 Vps5 PF09325.10 GAN07172.1 - 0.037 13.6 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Vps5 C terminal like DUF1664 PF07889.12 GAN07172.1 - 0.077 13.0 0.5 0.099 12.7 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SPA PF08616.10 GAN07173.1 - 1.8e-37 127.8 0.0 4.1e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 GAN07173.1 - 5.6e-23 81.9 4.1 2.9e-18 66.6 0.0 3.4 2 1 1 3 3 3 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 GAN07173.1 - 1.7e-10 40.1 0.6 0.00031 19.5 0.0 4.2 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 GAN07173.1 - 2.2e-07 30.7 0.0 0.0097 15.5 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) Skp1 PF01466.19 GAN07174.1 - 2.3e-27 94.8 0.4 4.3e-27 94.0 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAN07174.1 - 6.4e-27 93.5 0.2 1.5e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain ATP_bind_1 PF03029.17 GAN07175.1 - 9.6e-79 264.6 1.2 1.1e-78 264.4 0.3 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 GAN07175.1 - 2.5e-06 27.2 0.3 9.8e-05 22.0 0.3 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 GAN07175.1 - 6.6e-05 22.2 2.2 0.0091 15.2 0.0 2.7 2 1 1 3 3 3 1 G-protein alpha subunit MeaB PF03308.16 GAN07175.1 - 0.00012 21.1 0.1 0.21 10.5 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 GAN07175.1 - 0.00021 21.1 0.0 0.00077 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN07175.1 - 0.00023 21.3 0.0 0.0006 20.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 GAN07175.1 - 0.00026 20.6 0.0 0.0066 16.0 0.0 2.8 2 1 1 3 3 3 1 Ferrous iron transport protein B AAA_22 PF13401.6 GAN07175.1 - 0.00043 20.6 0.0 0.0016 18.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 GAN07175.1 - 0.00044 19.9 0.0 1.1 8.8 0.0 2.6 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAN07175.1 - 0.00086 19.7 0.5 0.0021 18.5 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 GAN07175.1 - 0.00097 18.4 0.3 0.0034 16.6 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.23 GAN07175.1 - 0.0015 18.6 0.0 0.0096 16.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 GAN07175.1 - 0.0021 18.0 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 GAN07175.1 - 0.0024 17.4 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Arf PF00025.21 GAN07175.1 - 0.0041 16.6 0.0 0.57 9.6 0.0 2.8 2 1 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 GAN07175.1 - 0.0053 16.5 0.1 0.19 11.5 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 GAN07175.1 - 0.0063 16.2 0.0 0.039 13.6 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 GAN07175.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 GAN07175.1 - 0.013 15.2 0.0 0.068 12.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 GAN07175.1 - 0.015 15.6 0.0 0.051 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAN07175.1 - 0.025 14.5 1.8 0.074 12.9 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAN07175.1 - 0.028 14.9 1.9 0.3 11.6 0.0 3.0 2 1 1 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 GAN07175.1 - 0.047 13.4 0.4 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase KAP_NTPase PF07693.14 GAN07175.1 - 0.054 12.7 0.6 0.49 9.6 0.6 2.4 1 1 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.20 GAN07175.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.6 GAN07175.1 - 0.095 12.7 0.1 2.3 8.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAN07175.1 - 0.15 11.4 1.0 2.3 7.5 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family PP2C_C PF07830.13 GAN07175.1 - 0.15 12.5 3.3 0.58 10.7 3.3 2.0 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Fumerase PF05681.14 GAN07175.1 - 0.19 11.1 1.6 1.6 8.1 1.4 2.1 2 0 0 2 2 2 0 Fumarate hydratase (Fumerase) AAA PF00004.29 GAN07175.1 - 0.2 12.1 1.3 28 5.2 0.7 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GAN07175.1 - 0.21 12.0 6.0 2.2 8.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 GAN07175.1 - 0.27 11.4 2.5 2.6 8.3 0.0 3.0 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAN07175.1 - 0.6 9.5 3.8 2.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit EBV-NA3 PF05009.12 GAN07175.1 - 1.7 8.1 5.2 2.8 7.4 5.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-B_dimeris PF09026.10 GAN07175.1 - 7.7 7.0 12.7 16 5.9 12.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TPR_1 PF00515.28 GAN07176.1 - 5.2e-13 48.2 1.2 0.00057 19.6 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN07176.1 - 6.5e-11 41.5 0.3 0.023 14.8 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.24 GAN07176.1 - 6.1e-10 38.9 1.3 1.3e-09 37.8 1.3 1.5 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.6 GAN07176.1 - 7e-08 33.0 0.1 0.00038 21.0 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN07176.1 - 1.2e-05 25.1 0.0 0.14 12.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN07176.1 - 3.6e-05 24.1 0.1 4.2 8.2 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN07176.1 - 0.00016 21.8 0.0 0.53 10.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN07176.1 - 0.00024 20.7 0.0 0.0065 16.1 0.0 3.1 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 GAN07176.1 - 0.00035 20.7 0.1 0.12 12.5 0.0 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN07176.1 - 0.0097 15.9 0.0 0.1 12.7 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN07176.1 - 0.01 16.1 0.0 8.3 6.8 0.0 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07176.1 - 0.038 14.8 0.1 0.26 12.2 0.0 2.5 2 1 0 2 2 1 0 Tetratricopeptide repeat DUF1186 PF06685.11 GAN07176.1 - 0.045 13.1 1.7 0.07 12.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) G_path_suppress PF15991.5 GAN07176.1 - 0.15 12.2 8.6 1 9.5 3.1 2.2 1 1 1 2 2 2 0 G-protein pathway suppressor Aldedh PF00171.22 GAN07177.1 - 1.2e-179 597.7 0.0 1.4e-179 597.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAN07177.1 - 0.015 14.8 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) UPF0697 PF15117.6 GAN07178.1 - 0.27 11.3 0.4 0.36 10.9 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 DUF4191 PF13829.6 GAN07178.1 - 1 8.7 2.9 1.1 8.6 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PAM2 PF07145.15 GAN07179.1 - 0.0016 18.0 3.9 1.9 8.3 0.7 4.0 3 0 0 3 3 3 2 Ataxin-2 C-terminal region ASD1 PF08688.10 GAN07179.1 - 0.063 13.7 4.6 0.25 11.7 4.6 2.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 Dicty_REP PF05086.12 GAN07179.1 - 0.11 10.5 8.0 0.18 9.7 8.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box-like PF12937.7 GAN07180.1 - 1.3e-11 44.2 4.1 1.4e-11 44.1 2.5 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN07180.1 - 7.2e-07 28.9 3.2 2e-06 27.5 3.2 1.8 1 0 0 1 1 1 1 F-box domain DOT1 PF08123.13 GAN07181.1 - 2.5e-07 30.5 0.0 4.2e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 GAN07181.1 - 5.2e-06 27.1 0.0 8.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN07181.1 - 5.7e-05 22.9 0.0 7.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAN07181.1 - 0.0015 18.6 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 GAN07181.1 - 0.0015 17.6 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 GAN07181.1 - 0.0023 18.6 0.1 0.0044 17.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAN07181.1 - 0.0039 16.5 0.1 0.0054 16.0 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 GAN07181.1 - 0.017 14.5 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GAN07181.1 - 0.035 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 GAN07181.1 - 0.037 14.7 0.0 0.063 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAN07181.1 - 0.038 13.8 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 GAN07181.1 - 0.04 13.6 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein MetW PF07021.12 GAN07181.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 GAN07181.1 - 0.17 11.2 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HMA PF00403.26 GAN07182.1 - 6.9e-62 205.8 3.1 4.2e-15 55.9 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 GAN07182.1 - 1.8e-44 151.4 1.8 1.8e-44 151.4 1.8 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAN07182.1 - 1.2e-38 133.5 0.1 2.4e-38 132.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN07182.1 - 8.1e-05 22.5 0.5 0.0053 16.5 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase JIP_LZII PF16471.5 GAN07182.1 - 0.07 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II RRM_3 PF08777.11 GAN07182.1 - 0.12 12.4 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Fer2_BFD PF04324.15 GAN07182.1 - 0.25 11.7 7.9 17 5.8 0.1 4.7 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain Cnd2 PF05786.14 GAN07183.1 - 2.6e-147 492.7 52.1 6.7e-145 484.7 52.1 3.0 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GAN07183.1 - 0.23 11.7 0.0 0.23 11.7 0.0 3.1 2 1 1 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CDC45 PF02724.14 GAN07183.1 - 4.7 5.4 13.9 12 4.0 13.9 1.7 1 0 0 1 1 1 0 CDC45-like protein ERGIC_N PF13850.6 GAN07185.1 - 0.023 15.0 2.1 3.7 7.9 0.3 4.0 2 2 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Gemini_mov PF01708.16 GAN07185.1 - 0.12 12.1 0.9 3.7 7.4 0.2 3.1 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF5527 PF17665.1 GAN07185.1 - 0.41 10.2 5.9 5.4 6.6 0.0 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5527) 2OG-FeII_Oxy_2 PF13532.6 GAN07187.1 - 1.5e-38 133.0 0.0 2.1e-36 125.9 0.0 2.3 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily SpoIISB_antitox PF14185.6 GAN07187.1 - 1.2 9.1 5.0 7.5 6.5 4.3 2.5 2 1 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system UCR_UQCRX_QCR9 PF05365.12 GAN07188.1 - 2.2e-27 94.8 4.2 2.4e-27 94.6 4.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like ParA PF10609.9 GAN07189.1 - 1.7e-100 335.6 1.9 1.9e-100 335.4 1.9 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAN07189.1 - 2e-12 47.3 0.0 4.2e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAN07189.1 - 3e-09 37.0 1.7 5.7e-07 29.6 0.3 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 GAN07189.1 - 1.6e-07 30.9 0.1 2.7e-07 30.1 0.1 1.3 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 GAN07189.1 - 1e-06 28.5 0.3 3.7e-05 23.3 0.3 2.2 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 GAN07189.1 - 0.00088 18.5 2.6 0.0039 16.4 1.4 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 GAN07189.1 - 0.0039 16.8 1.0 0.0074 15.9 1.0 1.4 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 GAN07189.1 - 0.026 13.8 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein PhnA_Zn_Ribbon PF08274.12 GAN07189.1 - 0.086 12.8 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon CobA_CobO_BtuR PF02572.15 GAN07189.1 - 0.69 10.2 2.2 1.4 9.1 2.2 1.6 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP EXS PF03124.14 GAN07190.1 - 1.6e-57 195.4 17.7 1.8e-57 195.2 17.7 1.0 1 0 0 1 1 1 1 EXS family F-box-like PF12937.7 GAN07191.1 - 2.5e-06 27.3 0.1 6.8e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN07191.1 - 0.031 14.2 0.1 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 F-box domain PPR_2 PF13041.6 GAN07192.1 - 4.9e-41 138.7 5.7 8.4e-08 32.3 0.4 7.3 4 2 4 8 8 8 6 PPR repeat family PPR_3 PF13812.6 GAN07192.1 - 1.1e-33 115.2 7.6 2.3e-10 40.4 0.0 6.7 4 3 3 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 GAN07192.1 - 1.9e-25 87.3 4.2 4.1e-07 29.8 0.0 8.0 8 0 0 8 8 8 5 PPR repeat PPR_long PF17177.4 GAN07192.1 - 1.3e-17 63.9 4.3 5.6e-09 35.7 0.4 3.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAN07192.1 - 1.2e-16 60.1 0.0 2.1e-05 24.1 0.0 6.9 9 0 0 9 9 9 4 PPR repeat TPR_7 PF13176.6 GAN07192.1 - 0.002 18.0 0.0 0.0084 16.1 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN07192.1 - 0.0083 15.5 0.6 0.036 13.5 0.6 2.0 2 1 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 GAN07192.1 - 0.037 14.3 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07192.1 - 0.053 14.4 0.0 60 4.9 0.0 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat ENT PF03735.14 GAN07192.1 - 0.082 13.0 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 ENT domain RPM2 PF08579.11 GAN07192.1 - 0.22 11.9 7.6 15 6.0 0.0 4.3 3 2 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) FAA_hydrolase PF01557.18 GAN07193.1 - 4.8e-61 206.2 0.0 8.5e-61 205.4 0.0 1.3 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 GAN07194.1 - 1.9e-31 109.1 0.1 4.2e-31 108.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFA PF04828.14 GAN07194.1 - 6.9e-14 52.0 0.1 6.9e-14 52.0 0.1 3.0 4 0 0 4 4 4 1 Glutathione-dependent formaldehyde-activating enzyme Zn_clus PF00172.18 GAN07194.1 - 1.9e-05 24.7 9.8 1.9e-05 24.7 9.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAN07195.1 - 2.1e-39 135.4 36.9 2.7e-39 135.1 36.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.11 GAN07196.1 - 3.6e-20 71.4 2.2 2.7e-17 62.2 0.5 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GAN07196.1 - 0.00017 21.2 0.0 0.064 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAN07196.1 - 0.00018 21.4 0.4 0.00018 21.4 0.4 1.6 2 0 0 2 2 2 1 AraC-like ligand binding domain DMSP_lyase PF16867.5 GAN07196.1 - 0.068 12.8 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase FAD_binding_3 PF01494.19 GAN07197.1 - 5.6e-30 104.8 0.0 6.9e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAN07197.1 - 3.9e-09 36.1 0.6 2e-05 24.0 0.6 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN07197.1 - 6.6e-08 32.5 6.0 0.00083 19.0 4.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAN07197.1 - 4.2e-07 30.4 3.6 0.00031 21.2 1.4 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN07197.1 - 7.3e-07 29.3 0.4 1.8e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAN07197.1 - 1.5e-06 27.5 2.8 2.6e-06 26.8 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 GAN07197.1 - 1.4e-05 24.2 0.4 0.019 13.9 0.6 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 GAN07197.1 - 0.00011 21.7 0.3 0.017 14.4 0.4 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAN07197.1 - 0.00028 20.4 3.7 0.00094 18.6 3.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAN07197.1 - 0.00031 19.9 0.7 0.00056 19.1 0.7 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAN07197.1 - 0.00033 19.5 1.5 0.00073 18.4 1.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 GAN07197.1 - 0.00093 18.3 1.5 0.012 14.7 1.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAN07197.1 - 0.0033 16.7 1.4 0.01 15.1 1.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 GAN07197.1 - 0.042 13.7 0.4 0.12 12.2 0.4 1.7 1 0 0 1 1 1 0 Rossmann-like domain AlaDh_PNT_C PF01262.21 GAN07197.1 - 0.17 11.1 1.3 0.3 10.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAN07197.1 - 0.18 12.3 0.1 0.43 11.0 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pantoate_ligase PF02569.15 GAN07198.1 - 3.7e-96 321.4 0.1 4.2e-96 321.2 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase EF-hand_13 PF17958.1 GAN07199.1 - 1.7e-21 75.8 0.0 9.7e-21 73.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 GAN07199.1 - 3e-11 43.6 0.6 1.7e-09 38.0 0.0 4.0 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 GAN07199.1 - 0.0001 22.1 0.7 0.072 13.0 0.0 5.1 7 0 0 7 7 7 1 EF-hand domain pair EF-hand_6 PF13405.6 GAN07199.1 - 0.0054 16.6 0.4 2.1 8.5 0.0 4.4 5 0 0 5 5 5 1 EF-hand domain Excalibur PF05901.11 GAN07199.1 - 0.014 16.0 0.1 5.8 7.6 0.0 3.5 3 0 0 3 3 3 0 Excalibur calcium-binding domain EF-hand_5 PF13202.6 GAN07199.1 - 0.048 13.2 0.0 0.048 13.2 0.0 3.1 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.32 GAN07199.1 - 0.41 10.3 0.0 0.41 10.3 0.0 3.9 6 0 0 6 6 6 0 EF hand DDE_3 PF13358.6 GAN07200.1 - 1.5e-09 37.7 0.2 1.9e-09 37.4 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease USP7_ICP0_bdg PF12436.8 GAN07201.1 - 2.8e-71 239.6 4.5 3.3e-69 232.8 0.9 2.8 3 0 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 GAN07201.1 - 1e-55 188.6 0.5 1e-55 188.6 0.5 3.4 3 1 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 GAN07201.1 - 1.8e-49 168.6 0.1 3e-49 167.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN07201.1 - 3.5e-20 72.8 0.0 1.7e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GAN07201.1 - 2.3e-09 37.4 0.1 9.8e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 MATH domain DUF4337 PF14235.6 GAN07202.1 - 0.0074 16.4 0.2 0.0078 16.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) P4Ha_N PF08336.11 GAN07202.1 - 0.0086 16.1 1.2 0.0098 15.9 1.2 1.0 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region GrpE PF01025.19 GAN07202.1 - 0.011 15.4 4.1 0.012 15.3 4.1 1.0 1 0 0 1 1 1 0 GrpE DUF507 PF04368.13 GAN07202.1 - 0.04 13.8 1.7 0.05 13.5 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Herpes_BLRF2 PF05812.12 GAN07202.1 - 0.053 13.7 3.1 0.069 13.3 1.0 1.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein SGIII PF15467.6 GAN07202.1 - 0.06 12.6 1.9 0.064 12.5 1.9 1.0 1 0 0 1 1 1 0 Secretogranin-3 Myb_DNA-bind_5 PF13873.6 GAN07202.1 - 0.062 13.4 1.6 0.074 13.1 1.6 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF4407 PF14362.6 GAN07202.1 - 0.062 12.6 0.2 0.065 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_Mu_Gam PF07352.12 GAN07202.1 - 0.065 13.1 4.0 0.072 13.0 4.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Dna2 PF08696.11 GAN07202.1 - 0.067 13.0 0.8 0.077 12.8 0.8 1.0 1 0 0 1 1 1 0 DNA replication factor Dna2 FAP206 PF12018.8 GAN07202.1 - 0.1 12.1 2.2 0.12 11.9 2.0 1.2 1 1 0 1 1 1 0 Domain of unknown function HGAL PF15666.5 GAN07202.1 - 0.13 12.4 0.8 0.16 12.1 0.8 1.1 1 0 0 1 1 1 0 Germinal center-associated lymphoma ING PF12998.7 GAN07202.1 - 0.21 12.2 3.2 0.24 12.0 3.2 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ORMDL PF04061.14 GAN07203.1 - 1.1e-47 161.3 2.8 1.3e-47 161.0 2.8 1.1 1 0 0 1 1 1 1 ORMDL family Cyclin PF08613.11 GAN07204.1 - 2.2e-09 37.9 0.1 2.2e-09 37.9 0.1 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAN07204.1 - 0.0013 18.4 0.4 0.0036 17.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain HAD_2 PF13419.6 GAN07204.1 - 0.11 12.6 2.0 0.76 9.8 0.4 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 GAN07205.1 - 1.3e-08 34.8 9.5 2.9e-08 33.7 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 GAN07206.1 - 1.3e-38 133.0 0.1 4.3e-38 131.3 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 Kelch_4 PF13418.6 GAN07207.1 - 2.6e-11 43.3 12.5 5.3e-07 29.6 0.1 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN07207.1 - 4.8e-09 36.2 14.3 0.16 12.3 0.2 6.5 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 GAN07207.1 - 2.5e-07 30.8 18.2 5e-05 23.5 0.4 5.1 5 0 0 5 5 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN07207.1 - 1e-06 28.5 3.4 0.019 14.9 0.0 5.3 5 0 0 5 5 5 1 Kelch motif Podoplanin PF05808.11 GAN07207.1 - 0.0032 17.6 0.8 0.016 15.3 0.2 2.3 2 0 0 2 2 2 1 Podoplanin SKG6 PF08693.10 GAN07207.1 - 0.0046 16.3 1.0 0.01 15.2 1.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_5 PF13854.6 GAN07207.1 - 0.0046 16.9 0.7 0.026 14.5 0.2 5.9 6 0 0 6 6 6 2 Kelch motif DUF5305 PF17231.2 GAN07207.1 - 0.0095 15.4 0.3 0.056 12.8 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5305) CYYR1 PF10873.8 GAN07207.1 - 0.018 15.5 0.1 0.048 14.1 0.1 1.7 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 VSP PF03302.13 GAN07207.1 - 0.02 13.8 0.9 0.035 13.0 0.9 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 GAN07207.1 - 0.023 15.5 0.0 0.051 14.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TSGP1 PF07771.11 GAN07207.1 - 0.2 11.8 0.4 0.46 10.7 0.4 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 FeoB_associated PF12669.7 GAN07207.1 - 0.58 10.6 3.0 1.2 9.6 3.0 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein BLACT_WH PF17778.1 GAN07208.1 - 1.1e-15 57.3 1.9 2.4e-15 56.3 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 GAN07208.1 - 1.1e-12 48.4 2.2 2.8e-12 47.1 2.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN07208.1 - 6e-05 22.6 1.7 0.00021 20.9 1.7 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAN07208.1 - 0.0004 20.3 0.3 0.00066 19.6 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HNH_3 PF13392.6 GAN07208.1 - 0.062 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease Lactamase_B_6 PF16661.5 GAN07208.1 - 0.087 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain CNH PF00780.22 GAN07209.1 - 8.5e-10 38.7 0.1 0.0028 17.3 0.1 3.2 3 0 0 3 3 3 3 CNH domain DEAD PF00270.29 GAN07211.1 - 1e-46 158.9 0.0 2e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN07211.1 - 1e-30 106.3 0.0 1.1e-27 96.5 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAN07211.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAN07211.1 - 0.0092 15.4 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 GAN07211.1 - 0.091 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase MRI PF15325.6 GAN07211.1 - 0.34 12.0 2.9 0.38 11.9 1.4 1.8 1 1 0 1 1 1 0 Modulator of retrovirus infection DUF1542 PF07564.11 GAN07212.1 - 0.13 12.4 0.5 0.27 11.4 0.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) MLD PF11647.8 GAN07212.1 - 0.47 10.8 2.9 0.31 11.3 1.0 1.6 2 0 0 2 2 2 0 Membrane Localization Domain AdoHcyase PF05221.17 GAN07214.1 - 1.9e-132 440.9 0.0 1.3e-71 241.2 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GAN07214.1 - 9.3e-86 285.9 3.2 1.5e-85 285.3 3.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAN07214.1 - 9.1e-09 34.9 0.1 1.9e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAN07214.1 - 8.9e-05 22.1 0.2 0.00015 21.4 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 GAN07214.1 - 0.0051 17.1 0.1 0.0097 16.2 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.6 GAN07214.1 - 0.052 14.0 0.1 0.092 13.2 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein AAA_31 PF13614.6 GAN07214.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain FG-GAP PF01839.23 GAN07215.1 - 9e-12 44.9 5.1 1e-05 25.5 0.6 4.1 5 0 0 5 5 5 2 FG-GAP repeat Zn_dep_PLPC PF00882.18 GAN07215.1 - 9.5e-10 38.8 1.4 2.2e-09 37.6 1.4 1.5 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 GAN07215.1 - 2.8e-07 31.0 2.6 1.8e-05 25.2 1.7 3.5 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 GAN07215.1 - 0.00014 22.1 0.0 0.0017 18.5 0.0 3.0 4 0 0 4 4 4 1 FG-GAP repeat XFP PF03894.15 GAN07215.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Ank_2 PF12796.7 GAN07217.1 - 5.7e-21 74.9 7.8 4.2e-09 36.9 0.6 4.8 2 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN07217.1 - 2.5e-16 58.1 10.3 0.057 14.0 0.1 8.9 8 1 2 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 GAN07217.1 - 1.6e-10 41.3 7.6 0.11 13.1 0.2 6.1 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAN07217.1 - 7.8e-06 26.1 12.0 6 7.5 0.2 7.8 5 3 2 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 GAN07217.1 - 2.2e-05 24.6 9.1 1.3 9.4 0.1 7.0 2 1 5 8 8 8 1 Ankyrin repeats (many copies) F-box-like_2 PF13013.6 GAN07217.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Phage_T7_Capsid PF05396.11 GAN07217.1 - 0.08 13.3 0.3 0.97 9.8 0.1 2.5 2 1 1 3 3 3 0 Phage T7 capsid assembly protein Kei1 PF08552.11 GAN07218.1 - 7.6e-20 71.6 16.5 2.4e-14 53.7 11.1 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 MARVEL PF01284.23 GAN07218.1 - 0.051 13.6 10.6 0.11 12.5 10.6 1.6 1 1 0 1 1 1 0 Membrane-associating domain Gemini_mov PF01708.16 GAN07218.1 - 0.13 12.1 0.6 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Geminivirus putative movement protein DNA_pol3_delta2 PF13177.6 GAN07219.1 - 8.8e-13 48.4 0.4 2.7e-12 46.8 0.1 2.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 GAN07219.1 - 1.1e-08 35.5 0.1 2.3e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAN07219.1 - 1.7e-08 34.6 0.1 2.8e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 GAN07219.1 - 0.00018 21.9 2.0 0.00021 21.6 0.1 2.1 3 0 0 3 3 3 1 Replication factor C C-terminal domain AAA_24 PF13479.6 GAN07219.1 - 0.00035 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 GAN07219.1 - 0.0016 18.3 0.3 0.0041 16.9 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 GAN07219.1 - 0.0018 18.7 1.1 0.039 14.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAN07219.1 - 0.0075 16.5 1.1 0.019 15.2 0.3 2.1 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 GAN07219.1 - 0.0091 15.9 1.4 0.68 9.7 1.4 2.5 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_33 PF13671.6 GAN07219.1 - 0.046 13.9 0.1 0.12 12.5 0.1 1.8 1 1 1 2 2 2 0 AAA domain Peptidase_S8 PF00082.22 GAN07220.1 - 3.5e-43 148.0 1.3 5.4e-43 147.4 1.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 GAN07220.1 - 1.5e-27 95.4 0.3 4.2e-27 94.0 0.3 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 GAN07220.1 - 0.0089 16.8 0.1 0.021 15.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Ima1_N PF09779.9 GAN07221.1 - 2.6e-25 89.9 8.9 2.6e-25 89.9 8.9 2.4 2 0 0 2 2 2 1 Ima1 N-terminal domain Shisa PF13908.6 GAN07221.1 - 0.011 16.0 0.2 0.011 16.0 0.2 2.7 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator DUF4428 PF14471.6 GAN07221.1 - 0.071 13.0 0.2 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF4834 PF16118.5 GAN07221.1 - 0.084 13.8 5.8 0.34 11.9 5.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) zinc_ribbon_6 PF14599.6 GAN07221.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.3 3 0 0 3 3 3 0 Zinc-ribbon Pex14_N PF04695.13 GAN07221.1 - 8.1 7.1 11.5 18 5.9 11.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C2H2 PF00096.26 GAN07224.1 - 0.016 15.7 3.1 0.016 15.7 3.1 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN07224.1 - 0.03 15.1 1.4 0.03 15.1 1.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.15 GAN07224.1 - 0.049 13.7 3.7 0.15 12.1 0.4 2.6 2 0 0 2 2 2 0 BED zinc finger zf-FCS PF06467.14 GAN07224.1 - 0.12 12.4 0.4 0.12 12.4 0.4 1.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif LIM PF00412.22 GAN07224.1 - 0.14 12.5 2.5 5.5 7.3 0.2 2.3 2 0 0 2 2 2 0 LIM domain zf-C2H2_2 PF12756.7 GAN07224.1 - 0.15 12.4 3.6 3.7 7.9 3.5 2.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Gin PF10764.9 GAN07224.1 - 0.16 12.0 1.1 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf_C2H2_ZHX PF18387.1 GAN07224.1 - 0.69 9.6 3.4 2.6 7.8 0.3 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 GAN07224.1 - 0.86 10.1 3.7 21 5.6 0.4 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 GAN07224.1 - 3.6 8.1 6.7 0.51 10.8 0.4 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type DNA_methylase PF00145.17 GAN07225.1 - 1.1e-38 133.5 0.0 1.2e-38 133.3 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Git3 PF11710.8 GAN07226.1 - 3 7.6 12.4 6.8 6.4 12.4 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TFR_dimer PF04253.15 GAN07227.1 - 1.5e-29 102.6 0.1 3e-29 101.6 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAN07227.1 - 1.1e-23 84.0 0.0 2.1e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAN07227.1 - 5.1e-11 42.4 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAN07227.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 GAN07227.1 - 0.0036 16.8 0.2 0.016 14.7 0.0 2.0 3 0 0 3 3 3 1 Nicastrin PSP PF04046.16 GAN07228.1 - 6.7e-13 48.3 0.3 1.6e-12 47.1 0.3 1.7 1 0 0 1 1 1 1 PSP zf-CCHC_2 PF13696.6 GAN07228.1 - 0.0037 17.1 4.1 0.009 15.8 4.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAN07228.1 - 0.007 16.4 6.1 0.013 15.6 6.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GAN07228.1 - 0.28 11.0 2.4 0.55 10.0 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Mito_carr PF00153.27 GAN07229.1 - 2.2e-62 207.0 1.4 6.5e-22 77.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.7 GAN07229.1 - 0.24 11.6 2.2 37 4.5 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Aminotran_5 PF00266.19 GAN07230.1 - 2.2e-27 96.0 0.0 2.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAN07230.1 - 0.0036 15.9 0.0 0.0054 15.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAN07230.1 - 0.015 14.5 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Tim17 PF02466.19 GAN07231.1 - 5.1e-34 117.0 7.7 6.7e-34 116.6 7.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABA_WDS PF02496.16 GAN07231.1 - 0.79 10.2 3.1 16 6.1 3.1 2.8 1 1 0 1 1 1 0 ABA/WDS induced protein VPS28 PF03997.12 GAN07232.1 - 1e-69 234.1 1.4 1.2e-69 233.8 1.4 1.1 1 0 0 1 1 1 1 VPS28 protein PKHD_C PF18331.1 GAN07232.1 - 0.12 12.5 0.1 0.35 11.0 0.1 1.8 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Dynamin_M PF01031.20 GAN07233.1 - 1.5e-103 346.0 0.0 9.7e-103 343.3 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 GAN07233.1 - 1.5e-52 178.0 1.5 2.3e-52 177.5 0.2 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 GAN07233.1 - 6.6e-29 99.9 0.7 6.6e-29 99.9 0.7 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAN07233.1 - 3.8e-05 23.7 0.0 0.079 13.0 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase JAKMIP_CC3 PF16034.5 GAN07233.1 - 0.014 15.4 2.3 0.025 14.5 2.3 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain Roc PF08477.13 GAN07233.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 GAN07234.1 - 7e-52 176.5 24.8 7e-52 176.5 24.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN07234.1 - 2.1e-11 43.4 8.0 2.1e-11 43.4 8.0 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 GAN07234.1 - 0.025 13.0 1.8 0.04 12.3 1.8 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DUF2207 PF09972.9 GAN07234.1 - 3.1 6.5 8.4 1.6 7.4 1.2 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DnaJ PF00226.31 GAN07235.1 - 1e-13 51.2 0.1 2.1e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L2_C PF03947.18 GAN07237.1 - 1.3e-53 180.5 1.7 1.3e-53 180.5 1.7 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAN07237.1 - 1.6e-25 88.9 0.3 2.9e-25 88.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Tctex-1 PF03645.13 GAN07240.1 - 0.019 15.2 0.1 0.026 14.7 0.1 1.2 1 0 0 1 1 1 0 Tctex-1 family Mg_trans_NIPA PF05653.14 GAN07241.1 - 4.4e-22 78.5 19.1 1.7e-21 76.7 19.1 1.7 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAN07241.1 - 0.00033 20.8 6.6 0.00033 20.8 6.6 3.1 3 1 0 3 3 3 1 EamA-like transporter family CUE PF02845.16 GAN07242.1 - 1.7e-08 34.0 0.2 8e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 GAN07242.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif ANAPC_CDC26 PF10471.9 GAN07242.1 - 0.036 14.9 1.0 0.036 14.9 1.0 4.0 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 MFS_1 PF07690.16 GAN07243.1 - 2.8e-35 121.9 28.9 3.8e-35 121.4 28.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAN07243.1 - 2.7e-06 26.9 10.6 2.7e-06 26.9 10.6 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RGS PF00615.19 GAN07244.1 - 6.1e-14 52.3 2.0 6.1e-14 52.3 2.0 1.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 GAN07244.1 - 1.3e-07 31.5 0.4 1.3e-07 31.5 0.4 1.6 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain DUF600 PF04634.12 GAN07244.1 - 0.28 11.2 4.0 0.52 10.4 3.5 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF600 Ribosomal_L30 PF00327.20 GAN07245.1 - 1.1e-10 41.2 0.1 3.2e-10 39.7 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAN07245.1 - 4.4e-07 30.0 11.2 4.4e-07 30.0 11.2 2.0 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Arf PF00025.21 GAN07246.1 - 2.6e-80 268.0 0.1 3e-80 267.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAN07246.1 - 3.2e-14 53.2 0.0 4.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAN07246.1 - 2e-13 50.2 1.0 2.3e-09 36.9 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAN07246.1 - 3.1e-13 49.5 0.0 3.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAN07246.1 - 6.6e-13 48.6 0.0 7.6e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAN07246.1 - 2e-10 40.5 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN07246.1 - 4.5e-06 26.7 0.0 8.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAN07246.1 - 0.0056 16.0 0.3 0.02 14.2 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TPR_1 PF00515.28 GAN07247.1 - 7.6e-12 44.5 9.8 0.02 14.7 0.2 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN07247.1 - 3.3e-09 36.2 19.4 0.19 11.9 0.3 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07247.1 - 4.7e-09 36.3 10.3 3.4 8.7 0.0 7.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN07247.1 - 6.8e-08 32.1 16.1 0.35 11.2 0.5 7.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAN07247.1 - 3.2e-06 27.1 5.4 0.32 11.5 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN07247.1 - 3.6e-06 27.4 9.4 0.096 13.2 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN07247.1 - 3.2e-05 24.5 11.0 4.4e-05 24.0 2.4 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN07247.1 - 0.0012 19.0 1.6 0.0012 19.0 1.6 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAN07247.1 - 0.0017 18.9 9.3 1.1 10.0 0.4 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN07247.1 - 0.0017 18.2 5.4 2.8 8.2 0.3 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF627 PF04781.12 GAN07247.1 - 0.12 12.4 0.2 0.39 10.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Alkyl_sulf_C PF14864.6 GAN07247.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal TPR_21 PF09976.9 GAN07247.1 - 0.13 12.0 6.1 0.048 13.4 1.2 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 GAN07247.1 - 0.15 11.7 13.0 0.92 9.2 0.2 5.6 7 0 0 7 7 7 0 TPR repeat SprA-related PF12118.8 GAN07247.1 - 0.53 9.4 6.3 1 8.5 6.3 1.4 1 0 0 1 1 1 0 SprA-related family ANAPC3 PF12895.7 GAN07247.1 - 1.1 9.6 11.8 0.2 11.9 0.5 4.0 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C48 PF02902.19 GAN07248.1 - 4.1e-22 79.1 0.2 8e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 GAN07248.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenovirus endoprotease DUF5598 PF18127.1 GAN07249.1 - 0.13 12.7 1.6 0.65 10.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5598) Cullin_binding PF03556.15 GAN07249.1 - 0.14 12.6 4.8 0.15 12.5 0.9 2.5 1 1 2 3 3 3 0 Cullin binding Pkinase PF00069.25 GAN07250.1 - 9.1e-58 195.7 0.0 1.2e-41 142.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07250.1 - 1.6e-24 86.6 0.0 1.3e-23 83.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN07250.1 - 3.1e-08 33.3 0.0 9.3e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAN07250.1 - 5.1e-07 29.3 0.1 8.1e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN07250.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN07250.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF3446 PF11928.8 GAN07250.1 - 0.0062 16.8 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 Early growth response N-terminal domain Choline_kinase PF01633.20 GAN07250.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 GAN07250.1 - 0.013 14.4 0.1 0.031 13.2 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain PDZ_5 PF17817.1 GAN07251.1 - 0.00092 19.4 0.3 0.0016 18.6 0.1 1.6 2 0 0 2 2 2 1 PDZ domain Med31 PF05669.12 GAN07251.1 - 0.028 14.4 0.3 0.063 13.3 0.2 1.6 1 1 1 2 2 2 0 SOH1 PAS_4 PF08448.10 GAN07251.1 - 0.038 14.2 0.1 0.044 14.0 0.1 1.0 1 0 0 1 1 1 0 PAS fold Bap31_Bap29_C PF18035.1 GAN07251.1 - 0.058 13.4 1.0 0.79 9.8 0.2 2.3 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mrr_N PF14338.6 GAN07251.1 - 0.084 13.0 0.4 0.15 12.2 0.2 1.5 1 1 1 2 2 2 0 Mrr N-terminal domain Ecl1 PF12855.7 GAN07252.1 - 1.8e-09 39.0 4.6 2.2e-09 38.7 4.6 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 GAN07252.1 - 0.054 13.0 1.8 0.1 12.1 1.8 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 CHCH PF06747.13 GAN07253.1 - 7.7e-08 32.3 3.4 1.4e-07 31.5 3.4 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 GAN07253.1 - 0.011 16.1 2.5 0.011 16.1 2.5 1.9 2 0 0 2 2 2 0 GCK domain Voldacs PF03517.13 GAN07253.1 - 0.1 12.7 5.8 0.12 12.5 0.6 2.1 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling P_C PF06640.11 GAN07253.1 - 0.49 10.5 6.1 0.078 13.1 1.1 1.9 1 1 1 2 2 2 0 P protein C-terminus NmrA PF05368.13 GAN07255.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family SAM_2 PF07647.17 GAN07256.1 - 0.0053 16.8 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 GAN07256.1 - 0.094 13.0 0.2 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) TSP9 PF11493.8 GAN07256.1 - 2.3 8.9 4.6 5.2 7.8 2.9 2.4 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 CDP-OH_P_transf PF01066.21 GAN07257.1 - 8.7e-14 52.0 0.4 8.7e-14 52.0 0.4 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Glutaredoxin PF00462.24 GAN07258.1 - 3e-22 78.6 0.1 3.9e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 GAN07258.1 - 3.4e-05 24.2 0.0 4.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 GAN07258.1 - 0.00013 22.3 0.0 0.00016 22.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 GAN07258.1 - 0.00024 21.5 0.1 0.00033 21.1 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 GAN07258.1 - 0.0016 18.2 0.6 0.039 13.7 0.2 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 GAN07258.1 - 0.016 15.2 0.1 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain GST_N_2 PF13409.6 GAN07258.1 - 0.033 14.5 0.0 0.043 14.1 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 GAN07258.1 - 0.035 14.1 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 GAN07258.1 - 0.043 14.0 0.7 2.8 8.1 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin Sad1_UNC PF07738.13 GAN07259.1 - 4.3e-29 101.2 0.0 9.5e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal FlgD PF03963.14 GAN07259.1 - 0.12 12.7 1.7 6.1 7.2 0.2 2.9 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region V-SNARE PF05008.15 GAN07259.1 - 0.44 11.0 2.8 15 6.0 0.2 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Importin_rep_6 PF18829.1 GAN07259.1 - 1.1 9.4 10.2 38 4.5 0.1 3.5 3 0 0 3 3 3 0 Importin repeat 6 adh_short_C2 PF13561.6 GAN07261.1 - 2e-50 171.6 0.0 2.4e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN07261.1 - 3.4e-43 147.4 0.0 4.3e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN07261.1 - 1.2e-09 38.4 0.1 1.6e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAN07261.1 - 0.00014 21.1 0.1 0.00016 20.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RVT_1 PF00078.27 GAN07262.1 - 7.4e-31 107.4 0.0 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FH2 PF02181.23 GAN07263.1 - 2.5e-83 280.3 9.4 2.5e-83 280.3 9.4 3.1 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAN07263.1 - 9.3e-46 155.8 0.0 9.3e-46 155.8 0.0 3.0 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAN07263.1 - 1.6e-44 151.8 2.2 1.6e-44 151.8 2.2 3.7 2 1 1 3 3 3 1 Diaphanous FH3 Domain DNA_pack_N PF02500.15 GAN07263.1 - 0.022 14.6 0.5 0.078 12.8 0.0 2.1 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus RPM2 PF08579.11 GAN07263.1 - 0.032 14.6 8.9 0.27 11.6 0.0 3.8 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Flu_M1_C PF08289.11 GAN07263.1 - 0.066 13.4 0.3 0.3 11.3 0.3 2.1 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF4145 PF13643.6 GAN07263.1 - 0.1 12.7 0.6 1.3 9.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) DUF4250 PF14056.6 GAN07263.1 - 3.9 7.5 6.2 1.6 8.7 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) RasGEF PF00617.19 GAN07264.1 - 1.1e-59 201.6 1.9 1.1e-59 201.6 1.9 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAN07264.1 - 7.9e-26 90.3 0.8 3.4e-25 88.3 0.8 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.26 GAN07264.1 - 6.3e-12 45.4 5.8 2.4e-08 33.9 0.5 2.6 2 0 0 2 2 2 2 WW domain CAS_C PF12026.8 GAN07264.1 - 0.00055 20.1 0.1 0.00055 20.1 0.1 3.5 4 0 0 4 4 4 1 Crk-Associated Substrate C-terminal domain SH3_2 PF07653.17 GAN07264.1 - 0.0095 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Velvet PF11754.8 GAN07265.1 - 1.2e-53 182.7 3.0 9.4e-35 120.7 0.6 4.3 1 1 2 3 3 3 2 Velvet factor S-antigen PF05756.11 GAN07266.1 - 0.24 11.8 3.7 0.14 12.6 1.2 1.8 1 1 1 2 2 2 0 S-antigen protein Stevor PF17410.2 GAN07266.1 - 0.62 9.6 3.0 1.5 8.3 3.0 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DNA_pol_phi PF04931.13 GAN07266.1 - 3 5.8 5.6 4 5.4 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 GAN07266.1 - 7.5 6.2 8.3 3.3 7.4 4.8 2.2 2 1 0 2 2 2 0 FAM176 family Mito_carr PF00153.27 GAN07267.1 - 2.8e-62 206.7 1.4 2e-22 78.9 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN07267.1 - 0.095 11.8 1.2 3.7 6.6 0.1 2.7 1 1 0 3 3 3 0 Gammaproteobacterial serine protease NAD_binding_2 PF03446.15 GAN07268.1 - 5e-44 150.3 0.3 6.7e-44 149.8 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAN07268.1 - 1e-27 96.8 0.0 1.8e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 GAN07268.1 - 0.00026 20.9 0.1 0.01 15.7 0.1 2.6 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAN07268.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 GAN07268.1 - 0.0036 17.5 0.0 0.016 15.5 0.0 2.0 1 1 1 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 GAN07268.1 - 0.0048 16.5 0.6 0.9 9.1 0.1 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 GAN07268.1 - 0.0057 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAN07268.1 - 0.027 13.8 0.3 0.054 12.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAN07268.1 - 0.047 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDH PF02153.17 GAN07268.1 - 0.058 12.4 0.1 0.094 11.7 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Rossmann-like PF10727.9 GAN07268.1 - 0.085 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain ThiF PF00899.21 GAN07268.1 - 0.14 11.5 0.1 0.44 9.8 0.1 1.7 1 1 1 2 2 2 0 ThiF family OPT PF03169.15 GAN07270.1 - 4.1e-190 633.5 53.9 5.1e-190 633.2 53.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Actin PF00022.19 GAN07271.1 - 5.2e-152 506.2 0.0 2e-151 504.2 0.0 1.7 1 1 0 1 1 1 1 Actin Ecl1 PF12855.7 GAN07272.1 - 1.6e-10 42.4 7.6 1.9e-10 42.2 7.6 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins ACI44 PF15270.6 GAN07272.1 - 0.064 13.5 3.0 0.093 12.9 3.0 1.2 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor zf-MYND PF01753.18 GAN07272.1 - 0.23 11.6 4.5 0.47 10.6 4.5 1.5 1 1 0 1 1 1 0 MYND finger DUF2116 PF09889.9 GAN07272.1 - 8.5 6.4 8.6 19 5.3 8.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Malic_M PF03949.15 GAN07274.1 - 3.3e-83 278.9 0.1 4.3e-83 278.5 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAN07274.1 - 1.7e-58 197.4 0.0 3e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RGS PF00615.19 GAN07275.1 - 1.7e-10 41.2 0.5 4.1e-09 36.7 0.5 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain PEMT PF04191.13 GAN07276.1 - 4.8e-55 184.5 10.3 1.4e-32 112.3 1.1 3.4 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 GAN07276.1 - 0.036 13.9 0.2 0.079 12.8 0.2 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Met_synt_B12 PF02965.17 GAN07276.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Arrestin_C PF02752.22 GAN07277.1 - 4.2e-16 59.6 0.1 6.7e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN07277.1 - 2.4e-10 40.6 0.0 7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN07277.1 - 0.00033 20.4 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Med27 PF11571.8 GAN07278.1 - 6.7e-14 52.0 0.8 1.6e-13 50.8 0.8 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 E1-E2_ATPase PF00122.20 GAN07280.1 - 5.3e-43 146.6 2.0 5.3e-43 146.6 2.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN07280.1 - 3.3e-41 141.0 6.9 3.3e-41 141.0 6.9 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAN07280.1 - 1.3e-24 87.7 0.1 3.9e-12 46.9 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN07280.1 - 9.2e-19 67.3 0.0 1.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN07280.1 - 4.7e-13 48.6 0.0 1.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN07280.1 - 2.1e-06 27.7 2.3 0.00011 22.0 0.5 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN07280.1 - 0.048 14.1 0.0 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ost4 PF10215.9 GAN07280.1 - 0.37 10.7 5.0 0.71 9.7 3.2 2.5 2 0 0 2 2 2 0 Oligosaccaryltransferase DUF4181 PF13789.6 GAN07280.1 - 9.5 6.5 9.2 18 5.6 3.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) EF1_GNE PF00736.19 GAN07281.1 - 2.8e-19 69.1 0.1 6.2e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 GAN07281.1 - 2.3e-07 31.1 2.4 2.3e-07 31.1 2.4 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 GAN07281.1 - 0.048 13.9 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DnaJ PF00226.31 GAN07281.1 - 0.094 12.9 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 DnaJ domain GST_C PF00043.25 GAN07281.1 - 0.19 12.0 0.6 2 8.7 0.0 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HLH PF00010.26 GAN07282.1 - 7.1e-13 48.3 2.0 1.7e-12 47.1 2.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L37 PF08561.10 GAN07282.1 - 0.011 16.3 6.3 0.021 15.3 6.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 HSP90 PF00183.18 GAN07282.1 - 0.016 14.2 1.0 0.016 14.2 1.0 2.2 1 1 1 2 2 2 0 Hsp90 protein PRP1_N PF06424.12 GAN07282.1 - 0.12 12.8 11.4 0.19 12.1 11.4 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CDC45 PF02724.14 GAN07282.1 - 0.13 10.5 14.3 0.17 10.1 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein MFMR_assoc PF16596.5 GAN07282.1 - 1 9.8 14.9 0.067 13.6 9.2 1.9 2 0 0 2 2 2 0 Disordered region downstream of MFMR SID-1_RNA_chan PF13965.6 GAN07282.1 - 1.4 7.2 6.1 1.9 6.8 6.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NRBF2 PF08961.10 GAN07282.1 - 2.2 7.9 17.2 1.2 8.7 14.5 1.9 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Presenilin PF01080.17 GAN07282.1 - 3.6 6.3 14.2 4.5 5.9 14.2 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GAN07282.1 - 9.7 5.3 6.7 12 5.0 6.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Syntaxin PF00804.25 GAN07283.1 - 1.7e-17 63.8 16.4 3.3e-17 62.8 16.4 1.5 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAN07283.1 - 5.4e-13 48.7 0.1 5.4e-13 48.7 0.1 2.7 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.6 GAN07283.1 - 2.8e-05 24.4 7.6 2.8e-05 24.4 7.6 2.7 3 1 0 3 3 2 1 Syntaxin-like protein Lipoprotein_6 PF01441.19 GAN07283.1 - 0.011 15.8 3.1 0.32 11.0 0.8 2.3 1 1 1 2 2 2 0 Lipoprotein DUF4709 PF15821.5 GAN07283.1 - 0.013 15.8 8.7 0.3 11.4 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) MCPsignal PF00015.21 GAN07283.1 - 0.015 15.1 2.0 0.015 15.1 2.0 3.0 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LMBR1 PF04791.16 GAN07283.1 - 0.015 14.2 5.2 0.023 13.7 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3040 PF11239.8 GAN07283.1 - 0.044 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2116 PF09889.9 GAN07283.1 - 0.045 13.7 0.5 0.1 12.6 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF745 PF05335.13 GAN07283.1 - 0.084 12.6 19.8 0.13 12.0 11.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF3671 PF12420.8 GAN07283.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function Syntaxin-6_N PF09177.11 GAN07283.1 - 0.13 12.8 13.6 0.84 10.2 2.3 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Sec20 PF03908.13 GAN07283.1 - 0.17 11.8 0.2 0.17 11.8 0.2 3.1 2 2 2 4 4 4 0 Sec20 T2SSF PF00482.23 GAN07283.1 - 0.24 11.3 5.0 1.3 9.0 1.3 3.0 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F NPV_P10 PF05531.12 GAN07283.1 - 0.35 11.4 9.0 1 9.8 0.6 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 GAN07283.1 - 0.79 10.2 12.8 0.91 10.0 0.3 3.5 1 1 4 5 5 5 0 Spectrin repeat SKA2 PF16740.5 GAN07283.1 - 1.4 8.7 13.0 1.1 9.1 2.5 3.2 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 2 Allexi_40kDa PF05549.11 GAN07283.1 - 1.5 8.3 9.8 0.29 10.6 2.8 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein MCU PF04678.13 GAN07283.1 - 3.1 7.9 11.0 0.13 12.4 1.3 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Fib_alpha PF08702.10 GAN07283.1 - 3.5 7.8 15.4 5 7.3 1.0 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Synaptobrevin PF00957.21 GAN07283.1 - 4.4 7.2 13.3 9 6.2 6.1 3.3 2 1 1 3 3 3 0 Synaptobrevin DUF4094 PF13334.6 GAN07283.1 - 4.7 7.7 7.0 1.4 9.4 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) DUF3347 PF11827.8 GAN07283.1 - 6.2 7.0 9.7 2.6 8.2 2.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3347) DUF2203 PF09969.9 GAN07283.1 - 6.7 7.5 14.4 2.7 8.8 2.7 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PALP PF00291.25 GAN07284.1 - 4.6e-78 262.6 0.1 5.8e-78 262.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 GAN07284.1 - 2e-42 142.8 0.0 3.8e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase MqsR_toxin PF15723.5 GAN07284.1 - 0.014 15.8 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA zf-PARP PF00645.18 GAN07285.1 - 0.018 15.9 0.1 0.055 14.3 0.1 1.9 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region SURF6 PF04935.12 GAN07286.1 - 3.4e-35 121.7 50.3 3.4e-35 121.7 50.3 2.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 GAN07286.1 - 4.7e-19 68.8 5.9 4.7e-19 68.8 5.9 6.1 5 1 0 5 5 5 2 60S ribosome biogenesis protein Rrp14 UPF0524 PF15823.5 GAN07286.1 - 3.1 7.1 7.4 4.8 6.5 5.7 2.1 1 1 1 2 2 2 0 UPF0524 of C3orf70 DIL PF01843.19 GAN07287.1 - 5.2e-26 90.9 3.8 5.2e-26 90.9 3.8 2.1 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 GAN07287.1 - 1.8e-16 60.4 0.0 6.1e-10 39.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN07287.1 - 2.3e-10 40.8 0.0 6.8e-05 23.3 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN07287.1 - 4.4e-08 33.3 0.0 4.8e-06 26.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAN07287.1 - 1.1e-07 32.0 0.0 0.058 13.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAN07287.1 - 3.5e-07 30.0 0.0 0.15 12.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Imm6 PF14434.6 GAN07287.1 - 0.025 14.5 0.8 0.12 12.3 0.0 2.6 3 0 0 3 3 3 0 Immunity protein Imm6 Ank_2 PF12796.7 GAN07288.1 - 2.9e-32 111.1 0.1 4.2e-17 62.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN07288.1 - 3.1e-31 107.3 0.2 4.4e-08 33.5 0.2 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN07288.1 - 1.3e-26 92.3 2.1 3e-07 30.6 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN07288.1 - 4e-22 75.9 1.4 0.00027 21.1 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 GAN07288.1 - 1.7e-20 72.5 0.7 9.9e-05 22.6 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 GAN07288.1 - 8.8e-17 61.0 8.7 1.7e-16 60.1 8.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger Pex24p PF06398.11 GAN07288.1 - 0.0015 17.6 4.3 0.0015 17.6 4.3 1.9 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin FYVE_2 PF02318.16 GAN07288.1 - 0.89 9.8 8.8 2.5 8.3 8.8 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger EF-hand_7 PF13499.6 GAN07289.1 - 5.5e-08 33.1 3.5 1e-07 32.3 3.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAN07289.1 - 6.6e-07 28.8 1.6 1.7e-06 27.5 1.6 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 GAN07289.1 - 0.0013 18.1 1.9 0.0013 18.1 1.9 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GAN07289.1 - 0.0042 16.5 4.4 0.01 15.3 4.4 1.7 1 0 0 1 1 1 1 EF hand EF_assoc_1 PF08355.12 GAN07289.1 - 0.06 12.9 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 EF hand associated EF-hand_8 PF13833.6 GAN07289.1 - 0.25 11.2 4.9 3 7.8 0.2 2.3 1 1 1 2 2 2 0 EF-hand domain pair HECT_2 PF09814.9 GAN07290.1 - 9.4e-47 159.7 5.4 1.2e-46 159.4 5.4 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Stc1 PF12898.7 GAN07290.1 - 0.18 12.4 0.3 0.18 12.4 0.3 2.5 3 0 0 3 3 3 0 Stc1 domain Yippee-Mis18 PF03226.14 GAN07290.1 - 3.3 8.0 5.4 26 5.1 5.2 2.5 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LRR_4 PF12799.7 GAN07291.1 - 4.1e-07 30.2 11.1 0.022 15.2 1.4 5.1 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN07291.1 - 0.00029 21.0 12.0 2.6 8.9 0.0 6.0 4 2 0 4 4 4 2 Leucine Rich Repeat F-box-like PF12937.7 GAN07291.1 - 0.0011 18.8 0.3 0.0026 17.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 GAN07291.1 - 0.025 14.3 7.5 1.3 8.8 0.2 4.3 3 2 0 3 3 3 0 Leucine rich repeat bPH_4 PF06713.11 GAN07291.1 - 0.053 13.6 0.5 0.092 12.8 0.5 1.4 1 0 0 1 1 1 0 Bacterial PH domain LRR_6 PF13516.6 GAN07291.1 - 0.74 10.0 14.0 3.4 8.0 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich repeat Ytp1 PF10355.9 GAN07292.1 - 1.1e-52 178.9 18.5 8.3e-51 172.8 18.5 2.8 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAN07292.1 - 7.6e-24 83.5 5.3 7.6e-24 83.5 5.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Kelch_5 PF13854.6 GAN07292.1 - 3.3e-15 55.7 3.2 0.0014 18.6 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 GAN07292.1 - 9.1e-12 44.8 10.5 0.19 12.0 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 GAN07292.1 - 1.1e-11 44.1 7.6 0.046 13.3 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 GAN07292.1 - 1.9e-07 31.0 9.6 0.014 15.4 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN07292.1 - 5.1e-06 26.6 10.4 0.28 11.5 0.1 6.2 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN07292.1 - 2.3e-05 24.1 3.2 1.4 9.0 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Cytochrom_B561 PF03188.16 GAN07292.1 - 0.00021 21.4 10.4 0.00021 21.4 10.4 3.6 4 1 0 4 4 4 1 Eukaryotic cytochrome b561 Gram_pos_anchor PF00746.21 GAN07292.1 - 0.0062 16.4 1.3 0.036 14.0 1.3 2.4 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Beta-APP PF03494.13 GAN07293.1 - 5.1 7.0 6.2 11 6.0 6.2 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Pkinase PF00069.25 GAN07294.1 - 4.1e-58 196.8 2.7 1.8e-56 191.4 2.7 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07294.1 - 1.1e-30 106.8 0.4 4e-29 101.7 0.4 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN07294.1 - 1.2e-11 44.5 0.0 2.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN07294.1 - 4.8e-07 28.9 0.3 6.1e-07 28.6 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAN07294.1 - 0.0012 18.8 0.1 0.0041 17.1 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN07294.1 - 0.0022 17.4 0.1 0.0056 16.1 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAN07294.1 - 0.013 15.2 2.0 0.1 12.2 0.0 2.6 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 GAN07294.1 - 0.026 14.0 2.0 0.035 13.6 0.0 2.1 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL PIP49_C PF12260.8 GAN07294.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Aldo_ket_red PF00248.21 GAN07295.1 - 8.2e-49 166.4 0.2 4.7e-47 160.6 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ArAE_2_N PF10337.9 GAN07296.1 - 6.1e-15 55.2 11.4 1.8e-12 47.1 3.1 2.7 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 GAN07296.1 - 2.4e-13 50.5 0.1 7.2e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 GAN07296.1 - 1.9e-07 31.2 15.1 1.9e-07 31.2 15.1 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.8 GAN07296.1 - 2.3e-05 23.5 0.2 2.3e-05 23.5 0.2 2.4 2 1 0 2 2 2 1 Aluminium activated malate transporter Haem_bd PF14376.6 GAN07297.1 - 0.035 14.0 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Haem-binding domain NSP10 PF09401.10 GAN07297.1 - 0.042 13.9 0.4 0.098 12.7 0.4 1.6 1 0 0 1 1 1 0 RNA synthesis protein NSP10 OrfB_Zn_ribbon PF07282.11 GAN07297.1 - 2.3 8.2 6.0 1.7 8.6 1.4 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain MFS_1 PF07690.16 GAN07298.1 - 3.2e-35 121.7 24.6 3.2e-35 121.7 24.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAN07298.1 - 8.5e-05 22.0 1.5 8.5e-05 22.0 1.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4231 PF14015.6 GAN07298.1 - 6.7 7.2 8.8 0.83 10.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 GAN07299.1 - 2.8e-38 131.7 30.2 2.8e-38 131.7 30.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAN07299.1 - 8.7e-06 25.3 4.5 8.7e-06 25.3 4.5 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 GAN07299.1 - 2 8.0 9.8 1.2 8.8 1.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 GAN07303.1 - 3.6e-61 206.8 0.0 4.3e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07303.1 - 2.3e-21 76.2 0.0 8e-21 74.5 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAN07303.1 - 1.6e-08 34.8 0.2 1.9e-05 24.7 0.3 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN07303.1 - 0.0036 16.1 0.2 0.027 13.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 GAN07303.1 - 0.017 14.7 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 GAN07303.1 - 0.039 13.3 0.3 0.09 12.1 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 GAN07303.1 - 0.078 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family WD40 PF00400.32 GAN07304.1 - 4.7e-40 134.8 15.1 4.2e-07 30.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 GAN07304.1 - 1.4e-09 37.6 0.1 2.7e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN07304.1 - 4e-09 36.2 0.1 7.2e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 GAN07304.1 - 0.00014 22.1 1.4 0.9 9.9 0.0 4.8 2 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 GAN07304.1 - 0.00061 18.8 1.5 0.015 14.3 0.0 3.1 2 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain F-box_4 PF15966.5 GAN07304.1 - 0.0067 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box Nup160 PF11715.8 GAN07304.1 - 0.0072 15.0 3.5 6.1 5.4 0.1 4.4 4 2 1 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 GAN07304.1 - 0.02 14.2 0.3 1.7 7.9 0.1 2.8 3 0 0 3 3 3 0 WD40-like domain PRANC PF09372.10 GAN07304.1 - 0.073 13.4 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 PRANC domain SAM_2 PF07647.17 GAN07305.1 - 5.4e-08 32.8 0.1 1.2e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN07305.1 - 9.2e-06 26.0 0.1 2e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Alginate_lyase PF05426.12 GAN07306.1 - 0.0015 18.2 0.1 0.0018 17.9 0.1 1.1 1 0 0 1 1 1 1 Alginate lyase Methyltransf_11 PF08241.12 GAN07307.1 - 2.7e-14 53.6 0.0 7.8e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN07307.1 - 2.4e-11 44.2 0.0 7.2e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN07307.1 - 4.7e-10 39.5 0.0 1.1e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN07307.1 - 2e-08 34.2 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN07307.1 - 3.3e-07 31.0 0.0 1e-06 29.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN07307.1 - 1.1e-05 24.9 0.1 1.6e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAN07307.1 - 0.0046 16.5 0.1 0.0081 15.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 GAN07307.1 - 0.033 13.9 0.1 0.083 12.6 0.1 1.6 1 1 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 GAN07307.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Glyco_hydro81C PF17652.1 GAN07308.1 - 5.3e-94 315.3 0.3 2e-92 310.1 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAN07308.1 - 4.4e-56 190.4 0.1 6.1e-56 189.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Cyclophil_like2 PF18050.1 GAN07308.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Cyclophilin-like family HA2 PF04408.23 GAN07309.1 - 7.3e-25 87.4 3.9 1.2e-24 86.7 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAN07309.1 - 4.6e-17 62.2 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAN07309.1 - 3.7e-12 46.6 0.1 2.2e-10 40.8 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN07309.1 - 1.6e-09 37.8 0.3 4e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAN07309.1 - 5.3e-08 33.2 0.1 1.5e-06 28.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAN07309.1 - 0.0023 18.3 1.2 0.0032 17.8 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 GAN07309.1 - 0.0036 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAN07309.1 - 0.0042 16.4 0.1 0.013 14.8 0.1 1.9 1 1 0 1 1 1 1 KaiC DUF2075 PF09848.9 GAN07309.1 - 0.0055 16.0 0.6 0.029 13.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GAN07309.1 - 0.0066 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 GAN07309.1 - 0.015 15.4 0.1 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAN07309.1 - 0.026 13.9 1.0 0.79 9.0 0.0 2.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.16 GAN07309.1 - 0.036 13.5 0.1 0.093 12.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein ATP_bind_2 PF03668.15 GAN07309.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop ATPase protein family ResIII PF04851.15 GAN07309.1 - 0.26 11.3 9.4 0.052 13.6 0.4 3.6 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Spore_GerAC PF05504.11 GAN07309.1 - 4.2 7.6 8.5 0.53 10.5 1.8 2.6 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal RRM_1 PF00076.22 GAN07310.1 - 0.044 13.6 0.0 2 8.3 0.0 2.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_11 PF13086.6 GAN07310.1 - 6.6 6.4 23.9 0.19 11.5 6.8 2.3 2 0 0 2 2 2 0 AAA domain Rhomboid PF01694.22 GAN07311.1 - 4.5e-27 94.9 8.9 6.9e-27 94.3 8.9 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 GAN07311.1 - 9.9e-05 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Peptidase_M75 PF09375.10 GAN07311.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Imelysin DUF1688 PF07958.11 GAN07312.1 - 1.9e-155 517.7 0.0 2.4e-155 517.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Glyco_hydro_18 PF00704.28 GAN07313.1 - 1.1e-20 74.6 0.7 8.5e-20 71.7 0.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2475 PF10629.9 GAN07313.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) RNA_pol_Rpb5_N PF03871.14 GAN07315.1 - 6.3e-31 106.8 0.0 1.1e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 GAN07315.1 - 7.1e-24 83.5 0.4 1.6e-23 82.4 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.12 GAN07315.1 - 0.077 13.0 0.0 0.25 11.4 0.0 1.8 1 1 1 2 2 2 0 Restriction endonuclease Phosphodiest PF01663.22 GAN07316.1 - 3.4e-12 46.6 0.2 5.7e-12 45.9 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 GAN07316.1 - 0.0029 17.0 0.2 0.006 16.0 0.2 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAN07316.1 - 0.017 14.5 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Sulfatase Aminotran_5 PF00266.19 GAN07317.1 - 2.9e-49 168.0 0.0 3.8e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Alpha_Helical PF18489.1 GAN07317.1 - 0.15 12.3 0.1 0.84 9.8 0.0 2.1 2 0 0 2 2 2 0 Alpha helical domain Sec23_trunk PF04811.15 GAN07318.1 - 1.4e-77 260.6 0.0 2.4e-77 259.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAN07318.1 - 2.7e-31 108.1 0.4 5.3e-31 107.2 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GAN07318.1 - 3.6e-24 84.5 0.1 8.1e-24 83.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GAN07318.1 - 1e-16 60.6 5.3 2e-16 59.7 5.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAN07318.1 - 1.5e-15 56.9 0.0 4.4e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Serglycin PF04360.12 GAN07319.1 - 0.11 12.4 1.4 0.21 11.5 1.4 1.5 1 0 0 1 1 1 0 Serglycin NAD_binding_6 PF08030.12 GAN07320.1 - 4.4e-17 62.6 0.1 1.6e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAN07320.1 - 1.1e-14 54.6 15.8 3.1e-14 53.2 8.6 2.4 2 0 0 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAN07320.1 - 1.2e-12 47.9 0.0 3.3e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 GAN07320.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF5305 PF17231.2 GAN07320.1 - 2.5 7.4 4.9 4.4 6.6 0.3 2.9 3 1 0 3 3 3 0 Family of unknown function (DUF5305) DDE_1 PF03184.19 GAN07321.1 - 0.013 15.2 0.6 0.053 13.2 0.2 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease MBOAT_2 PF13813.6 GAN07322.1 - 4.2e-09 36.5 1.7 4.2e-09 36.5 1.7 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PPR_2 PF13041.6 GAN07323.1 - 2e-09 37.5 0.8 2.6e-05 24.3 0.0 3.4 1 1 2 3 3 3 2 PPR repeat family PPR_3 PF13812.6 GAN07323.1 - 1.7e-07 31.2 0.2 9.3e-06 25.6 0.0 3.1 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 GAN07323.1 - 1.5e-06 28.0 0.2 0.018 15.3 0.0 3.5 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.7 GAN07323.1 - 0.00017 21.3 0.0 0.00087 18.9 0.0 2.1 2 0 0 2 2 2 1 PPR repeat MRP-S27 PF10037.9 GAN07323.1 - 0.00036 19.5 0.1 0.00076 18.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 GAN07323.1 - 0.00088 19.2 1.0 0.0044 16.9 0.4 2.4 2 1 0 2 2 2 1 Region in Clathrin and VPS PPR_long PF17177.4 GAN07323.1 - 0.0031 16.9 0.1 0.0053 16.2 0.1 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP DUF2989 PF11207.8 GAN07323.1 - 0.012 15.4 7.7 1.2 8.9 2.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2989) p25-alpha PF05517.12 GAN07323.1 - 0.055 13.6 0.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 p25-alpha TPR_19 PF14559.6 GAN07323.1 - 0.073 13.6 2.9 0.45 11.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 GAN07324.1 - 1.7e-18 67.2 0.2 2e-17 63.7 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN07324.1 - 9.9e-12 44.6 0.0 2.4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN07324.1 - 2e-09 38.4 0.0 2.5e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 GAN07324.1 - 3.3e-05 23.7 0.0 5.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GAN07324.1 - 0.012 15.1 0.1 2 7.8 0.1 3.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 GAN07324.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 GAN07324.1 - 0.096 12.4 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Med9 PF07544.13 GAN07325.1 - 1.1e-10 41.4 1.4 1.4e-10 41.1 1.4 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 4HB_MCP_1 PF12729.7 GAN07325.1 - 0.0077 15.8 1.7 0.02 14.4 0.1 1.9 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction Nsp1_C PF05064.13 GAN07326.1 - 6.2e-36 122.7 9.6 1.6e-35 121.4 9.6 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Interferon PF00143.19 GAN07326.1 - 0.042 14.0 9.1 0.13 12.5 0.6 2.2 2 0 0 2 2 2 0 Interferon alpha/beta domain TEX12 PF15219.6 GAN07326.1 - 0.41 11.0 2.0 23 5.4 0.1 2.8 1 1 2 3 3 3 0 Testis-expressed 12 DUF1664 PF07889.12 GAN07326.1 - 2.6 8.1 16.1 2.3 8.3 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 GAN07326.1 - 3.1 8.1 17.5 0.081 13.2 3.2 2.9 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-Q PF13094.6 GAN07326.1 - 8.9 6.5 11.0 26 5.0 11.0 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_2 PF07719.17 GAN07327.1 - 2.4e-11 42.8 0.0 0.00035 20.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN07327.1 - 6.8e-11 41.5 0.0 0.0016 18.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN07327.1 - 4.9e-06 26.1 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 GAN07327.1 - 4.6e-05 23.3 0.0 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN07327.1 - 0.0024 18.5 0.0 0.23 12.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 GAN07327.1 - 0.0034 17.5 0.1 0.049 13.7 0.1 2.1 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 GAN07327.1 - 0.0035 17.3 0.3 1.5 9.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07327.1 - 0.013 16.3 0.0 0.45 11.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN07327.1 - 0.026 14.8 0.3 4.3 7.7 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAN07327.1 - 0.049 13.8 0.1 0.085 13.0 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SPO22 PF08631.10 GAN07327.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Acetyltransf_1 PF00583.25 GAN07328.1 - 1.4e-08 35.0 0.0 1.9e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN07328.1 - 6.7e-05 23.2 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN07328.1 - 0.0003 20.7 0.0 0.0007 19.5 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 GAN07328.1 - 0.005 16.8 0.1 0.0087 16.0 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_1 PF00561.20 GAN07329.1 - 2.8e-18 66.5 0.1 1e-13 51.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN07329.1 - 3.4e-15 56.0 0.1 1.1e-14 54.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN07329.1 - 1.8e-11 45.1 0.0 2.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAN07329.1 - 0.0023 17.5 0.7 4.3 6.8 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 GAN07329.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 GAN07329.1 - 0.0091 15.9 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 GAN07329.1 - 0.038 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 GAN07329.1 - 0.04 13.9 0.0 0.07 13.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 GAN07329.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_1 PF00561.20 GAN07331.1 - 6.3e-25 88.3 0.1 2.2e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN07331.1 - 1.4e-17 63.8 0.1 3.8e-17 62.4 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN07331.1 - 1.3e-14 55.3 0.0 1.9e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GAN07331.1 - 8.7e-08 32.2 0.0 2.3e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Thioesterase PF00975.20 GAN07331.1 - 1.8e-05 25.0 0.0 7.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 GAN07331.1 - 2.5e-05 24.1 0.1 0.42 10.4 0.1 3.1 2 1 0 2 2 2 2 Alpha/beta hydrolase family End_N_terminal PF12218.8 GAN07331.1 - 0.033 13.9 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase DLH PF01738.18 GAN07331.1 - 0.034 13.7 0.0 3 7.3 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 GAN07331.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_2 PF01674.18 GAN07331.1 - 0.2 11.1 0.0 0.54 9.7 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 2) RE_LlaMI PF09562.10 GAN07332.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 LlaMI restriction endonuclease zf-RVT PF13966.6 GAN07333.1 - 2.2e-10 41.1 0.8 4.4e-10 40.1 0.8 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase TSC22 PF01166.18 GAN07335.1 - 0.0017 18.6 3.8 0.007 16.7 3.8 2.1 1 1 0 1 1 1 1 TSC-22/dip/bun family ASL_C PF08328.11 GAN07335.1 - 0.0086 16.2 2.5 0.01 16.0 1.5 1.6 1 1 0 1 1 1 1 Adenylosuccinate lyase C-terminal Phosphonate-bd PF12974.7 GAN07335.1 - 0.025 14.2 1.7 0.038 13.6 0.4 1.7 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Phage_antitermQ PF06530.12 GAN07335.1 - 0.028 14.3 0.6 0.049 13.5 0.6 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q ZapB PF06005.12 GAN07335.1 - 2 8.9 9.8 0.15 12.5 3.9 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Ribosomal_S3_C PF00189.20 GAN07336.1 - 1.4e-22 79.9 0.5 6.7e-22 77.8 0.8 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAN07336.1 - 1.6e-12 47.1 0.1 2.7e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GAN07336.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PNRC PF15365.6 GAN07337.1 - 1.1e-08 34.6 6.2 2.2e-08 33.7 6.2 1.5 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif Dehydrin PF00257.19 GAN07337.1 - 0.00058 20.5 7.8 0.00095 19.8 7.8 1.3 1 0 0 1 1 1 1 Dehydrin DUF1635 PF07795.11 GAN07337.1 - 0.19 11.6 13.9 0.15 11.9 10.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Presenilin PF01080.17 GAN07337.1 - 0.24 10.1 10.6 0.24 10.1 10.6 1.1 1 0 0 1 1 1 0 Presenilin Spem1 PF15670.5 GAN07337.1 - 0.27 10.8 10.1 0.33 10.5 10.1 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Ndc1_Nup PF09531.10 GAN07337.1 - 1 7.9 13.7 1.1 7.9 13.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 GAN07337.1 - 1.6 6.7 10.1 1.6 6.8 10.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.12 GAN07337.1 - 1.9 6.4 18.2 2.5 6.0 18.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.9 GAN07337.1 - 2.5 7.7 23.3 3.3 7.3 23.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Membralin PF09746.9 GAN07337.1 - 2.5 7.1 5.3 2.4 7.1 5.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Zip PF02535.22 GAN07337.1 - 2.6 7.2 7.1 2.6 7.2 7.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 GAN07337.1 - 4.6 7.2 14.1 6.3 6.7 14.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3537 PF12056.8 GAN07337.1 - 8.4 5.1 9.9 14 4.4 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) CAP_GLY PF01302.25 GAN07338.1 - 1.4e-18 66.6 0.1 2.6e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 GAN07338.1 - 1.7e-12 46.9 10.8 1.1e-06 28.3 2.5 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF3015 PF11220.8 GAN07338.1 - 0.59 10.0 5.5 7.2 6.5 5.5 3.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Cofilin_ADF PF00241.20 GAN07339.1 - 1.6e-12 47.3 0.0 2.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 GAN07339.1 - 7.2e-06 26.5 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAN07339.1 - 0.034 14.6 1.0 0.18 12.2 0.0 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain TFIIA PF03153.13 GAN07339.1 - 0.19 11.7 25.9 0.26 11.2 25.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 GAN07339.1 - 0.32 10.0 13.6 0.43 9.6 13.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4207 PF13904.6 GAN07339.1 - 0.37 10.4 31.0 0.57 9.8 31.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Borrelia_P83 PF05262.11 GAN07339.1 - 0.62 8.5 15.8 0.82 8.1 15.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.6 GAN07339.1 - 0.98 9.9 14.4 1.8 9.0 14.4 1.5 1 0 0 1 1 1 0 AAA domain DUF737 PF05300.11 GAN07339.1 - 4 7.8 29.1 6.9 7.0 29.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) eIF-3_zeta PF05091.12 GAN07339.1 - 4.7 6.1 15.6 6.7 5.6 15.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tfb4 PF03850.14 GAN07339.1 - 6.5 6.2 7.3 10 5.5 7.3 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 Asp-B-Hydro_N PF05279.11 GAN07339.1 - 7.3 6.6 26.9 9.9 6.1 26.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF966 PF06136.13 GAN07339.1 - 7.9 6.1 17.3 11 5.6 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mg_trans_NIPA PF05653.14 GAN07340.1 - 2.8e-94 315.6 26.9 3.6e-94 315.2 26.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAN07340.1 - 2.7e-06 27.6 7.2 2.7e-06 27.6 7.2 3.9 3 1 1 4 4 4 2 EamA-like transporter family SLATT_fungal PF18142.1 GAN07340.1 - 0.16 12.0 6.7 8.5 6.4 0.0 3.6 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain IncF PF17626.2 GAN07340.1 - 5 7.5 8.5 22 5.5 0.5 3.2 3 0 0 3 3 3 0 Inclusion membrane protein F Terpene_synth_C PF03936.16 GAN07341.1 - 0.086 12.2 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF3246 PF11596.8 GAN07341.1 - 5 6.5 20.4 2.6 7.4 13.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) AA_kinase PF00696.28 GAN07342.1 - 1.3e-39 136.2 0.5 2e-39 135.6 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 GAN07342.1 - 5.3e-07 29.5 0.7 1.3e-06 28.2 0.4 1.9 2 0 0 2 2 2 1 PUA domain UL16 PF17622.2 GAN07342.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Viral unique long protein 16 Nucleotid_trans PF03407.16 GAN07342.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Zn_clus PF00172.18 GAN07343.1 - 6.7e-09 35.7 10.2 1.4e-08 34.7 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leu_zip PF15294.6 GAN07343.1 - 0.058 12.9 2.6 0.12 11.9 2.6 1.4 1 0 0 1 1 1 0 Leucine zipper DUF4407 PF14362.6 GAN07343.1 - 1 8.7 4.9 2.3 7.5 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 GAN07343.1 - 7.7 5.6 6.9 29 3.8 6.9 1.9 1 1 0 1 1 1 0 ZIP Zinc transporter Enolase_C PF00113.22 GAN07344.1 - 9.2e-154 511.0 0.2 1.2e-153 510.6 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAN07344.1 - 1.4e-56 190.3 0.0 2.3e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAN07344.1 - 2.1e-05 24.2 0.1 4.3e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAN07344.1 - 0.0049 16.1 0.4 0.012 14.8 0.2 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Aldo_ket_red PF00248.21 GAN07345.1 - 1.4e-25 90.1 0.1 3.1e-23 82.4 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family TcA_TcB_BD PF18276.1 GAN07346.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain PAP2_3 PF14378.6 GAN07347.1 - 5.4e-24 84.9 9.1 8.2e-24 84.3 9.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 GAN07347.1 - 3.5e-10 39.8 3.8 3.5e-10 39.8 3.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 GAN07347.1 - 7.4 7.2 10.5 0.71 10.4 3.9 2.4 2 1 0 2 2 2 0 PAP2 superfamily C-terminal NUDIX PF00293.28 GAN07348.1 - 2.2e-12 47.2 0.1 3.6e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Frataxin_Cyay PF01491.16 GAN07349.1 - 2.9e-29 101.3 0.0 4.1e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF1262 PF06880.11 GAN07349.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) Rer1 PF03248.13 GAN07350.1 - 3.4e-55 186.4 2.3 3.8e-55 186.2 2.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 GAN07350.1 - 0.042 13.5 1.2 0.057 13.0 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) S4 PF01479.25 GAN07351.1 - 4.3e-12 45.5 1.2 4.3e-12 45.5 1.2 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 GAN07351.1 - 0.00017 22.4 0.0 0.0003 21.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 GAN07352.1 - 8.4e-38 128.3 1.2 1.1e-37 127.9 1.2 1.3 1 1 0 1 1 1 1 Ribosomal protein L21e NigD_C PF17415.2 GAN07352.1 - 0.089 12.9 0.0 0.96 9.5 0.0 2.1 2 0 0 2 2 2 0 NigD-like C-terminal beta sandwich domain LETM1 PF07766.13 GAN07353.1 - 5.9e-37 127.5 5.3 2.9e-21 76.0 0.5 2.1 1 1 1 2 2 2 2 LETM1-like protein SAP PF02037.27 GAN07353.1 - 0.027 14.2 0.6 1.2 9.0 0.0 3.3 3 1 1 4 4 4 0 SAP domain CENP-T_C PF15511.6 GAN07354.1 - 1.1e-12 48.0 0.2 3.3e-12 46.5 0.2 1.8 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Peptidase_M16_C PF05193.21 GAN07355.1 - 1.1e-28 100.5 0.0 3.1e-19 69.7 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAN07355.1 - 6.1e-10 39.3 0.4 1.9e-05 24.7 0.0 3.6 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 GAN07355.1 - 0.16 11.1 6.4 1 8.4 2.8 2.6 2 1 0 2 2 2 0 Peptidase M16C associated zf-met PF12874.7 GAN07356.1 - 1e-20 73.4 110.5 0.0016 18.8 0.7 15.9 16 0 0 16 16 16 8 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAN07356.1 - 9.8e-16 57.9 84.6 0.00054 20.3 0.4 12.7 4 4 9 13 13 13 8 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAN07356.1 - 3.7e-12 46.2 116.5 0.0006 20.0 1.4 15.6 16 0 0 16 16 16 9 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAN07356.1 - 9.2e-10 38.5 158.3 0.036 14.9 1.7 16.3 16 0 0 16 16 16 9 C2H2-type zinc finger DUF629 PF04780.12 GAN07356.1 - 2.9e-05 22.8 84.5 0.091 11.3 1.1 15.2 15 1 1 16 16 16 8 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 GAN07356.1 - 0.0067 16.0 66.6 2.6 7.7 0.1 13.9 14 0 0 14 14 14 4 Zinc-fingers and homeoboxes C2H2 finger domain Urb2 PF10441.9 GAN07356.1 - 0.0088 16.0 0.0 0.026 14.5 0.0 1.7 2 0 0 2 2 2 1 Urb2/Npa2 family zf-Dof PF02701.15 GAN07356.1 - 0.038 14.1 0.2 0.038 14.1 0.2 11.0 13 0 0 13 13 10 0 Dof domain, zinc finger PEHE PF15275.6 GAN07356.1 - 0.076 13.7 2.7 0.35 11.5 2.7 2.3 1 0 0 1 1 1 0 PEHE domain Chordopox_A33R PF05966.12 GAN07356.1 - 0.12 11.7 7.6 27 3.9 0.0 5.4 4 2 1 5 5 5 0 Chordopoxvirus A33R protein zf-BED PF02892.15 GAN07356.1 - 0.17 12.0 0.0 0.17 12.0 0.0 11.1 12 0 0 12 12 11 0 BED zinc finger ARS2 PF04959.13 GAN07356.1 - 0.97 9.8 4.4 0.38 11.1 0.5 2.4 2 1 0 2 2 2 0 Arsenite-resistance protein 2 DUF1062 PF06353.12 GAN07356.1 - 0.98 10.2 13.4 12 6.7 0.1 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF1062) DUF4674 PF15719.5 GAN07356.1 - 1.6 8.8 0.0 1.6 8.8 0.0 7.9 9 1 0 10 10 10 0 Domain of unknown function (DUF4674) Trm112p PF03966.16 GAN07356.1 - 1.9 9.2 10.2 24 5.6 0.1 5.6 6 1 0 6 6 6 0 Trm112p-like protein zf-AD PF07776.15 GAN07356.1 - 4.1 7.7 43.0 4.9 7.5 0.0 10.8 9 3 1 10 10 10 0 Zinc-finger associated domain (zf-AD) dCMP_cyt_deam_1 PF00383.23 GAN07357.1 - 1.1e-10 41.2 0.0 3.6e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAN07357.1 - 2.3e-08 33.9 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAN07357.1 - 0.013 15.6 0.2 0.12 12.5 0.2 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase Ribonuc_L-PSP PF01042.21 GAN07359.1 - 9.3e-44 148.3 0.3 1.1e-43 148.1 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP S36_mt PF10937.8 GAN07360.1 - 3.3e-11 44.8 2.2 1.8e-06 29.5 0.5 2.2 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial CALCOCO1 PF07888.11 GAN07361.1 - 0.01 14.8 11.9 0.013 14.4 11.9 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like SKA2 PF16740.5 GAN07361.1 - 0.088 12.6 7.1 0.23 11.3 1.8 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 KxDL PF10241.9 GAN07361.1 - 0.1 12.9 5.1 0.11 12.8 0.4 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein HAP1_N PF04849.13 GAN07361.1 - 0.15 11.2 12.8 0.098 11.8 7.2 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Cep57_CLD_2 PF14197.6 GAN07361.1 - 0.24 11.5 3.7 4.8 7.3 1.0 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 GAN07361.1 - 0.4 9.5 13.7 0.09 11.6 5.4 2.3 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF3450 PF11932.8 GAN07361.1 - 0.47 9.7 11.7 0.056 12.7 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.6 GAN07361.1 - 0.63 9.4 11.9 4.3 6.6 11.5 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 GAN07361.1 - 1 9.5 8.4 0.35 11.0 1.7 2.5 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4763 PF15960.5 GAN07361.1 - 1 8.6 8.4 2.6 7.3 8.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DUF2408 PF10303.9 GAN07361.1 - 1.2 9.7 6.3 6.5 7.3 6.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CENP-F_leu_zip PF10473.9 GAN07361.1 - 1.4 8.9 10.6 0.53 10.3 3.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 GAN07361.1 - 1.9 8.5 7.3 2.1 8.4 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ead_Ea22 PF13935.6 GAN07361.1 - 2.9 8.5 6.2 16 6.1 0.5 2.3 1 1 1 2 2 2 0 Ead/Ea22-like protein Fib_alpha PF08702.10 GAN07361.1 - 3 8.0 9.5 3.8 7.7 1.3 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 GAN07361.1 - 3.4 8.4 7.6 3.4e+02 1.9 7.5 2.6 1 1 0 1 1 1 0 Initiation control protein YabA DUF1117 PF06547.12 GAN07361.1 - 8.6 7.0 9.0 7.3 7.2 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1117) RRM_1 PF00076.22 GAN07362.1 - 4.6e-38 128.9 0.0 4.8e-18 64.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN07362.1 - 6.6e-07 29.2 0.0 0.0041 17.1 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAN07362.1 - 2.1e-06 27.5 0.0 0.019 14.8 0.0 2.8 2 2 0 2 2 2 2 Occluded RNA-recognition motif CPSF100_C PF13299.6 GAN07362.1 - 0.31 11.2 8.8 3.1 7.9 8.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RP-C_C PF11800.8 GAN07362.1 - 0.39 10.8 5.2 0.59 10.2 5.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4778 PF16008.5 GAN07362.1 - 0.4 10.7 2.3 0.51 10.4 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Sec62 PF03839.16 GAN07362.1 - 0.65 9.5 6.9 0.89 9.0 6.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SDA1 PF05285.12 GAN07362.1 - 0.69 9.3 15.6 0.91 8.9 15.6 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GAN07362.1 - 0.75 7.8 18.2 0.97 7.5 18.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi HSP90 PF00183.18 GAN07362.1 - 0.8 8.5 10.2 1 8.2 10.2 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.14 GAN07362.1 - 1.2 7.4 11.1 1.4 7.1 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GAN07362.1 - 5.1 5.8 8.2 6.4 5.4 8.2 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_M22 PF00814.25 GAN07363.1 - 0.0045 16.7 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.16 GAN07363.1 - 0.036 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Rsm22 PF09243.10 GAN07364.1 - 5.9e-69 232.4 0.0 7.8e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 GAN07364.1 - 2.5e-05 24.2 0.0 5.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN07364.1 - 2.8e-05 24.7 0.0 6.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN07364.1 - 3.6e-05 23.6 0.0 0.00055 19.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN07364.1 - 7e-05 23.5 0.0 0.00029 21.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN07364.1 - 0.0068 17.0 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN07364.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family HSP70 PF00012.20 GAN07365.1 - 1.1e-07 30.5 0.2 4.8e-07 28.4 0.1 2.0 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.20 GAN07365.1 - 0.036 13.6 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Biotin_carb_C PF02785.19 GAN07365.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain VHS PF00790.19 GAN07366.1 - 2e-28 99.0 0.0 5.4e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAN07366.1 - 8.4e-14 51.6 1.9 8.4e-14 51.6 1.9 2.8 3 0 0 3 3 3 1 GAT domain SurA_N_2 PF13623.6 GAN07366.1 - 0.33 10.8 4.4 0.89 9.4 4.4 1.7 1 0 0 1 1 1 0 SurA N-terminal domain PH PF00169.29 GAN07367.1 - 1.4e-07 32.0 0.8 3.4e-07 30.7 0.1 2.0 2 1 1 3 3 3 1 PH domain PH_16 PF17838.1 GAN07367.1 - 0.0015 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 GAN07367.1 - 0.017 14.9 0.7 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Rab_eff_C PF04698.12 GAN07367.1 - 0.044 12.1 6.4 0.051 11.9 6.4 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus DUF4483 PF14825.6 GAN07367.1 - 0.08 12.7 4.5 0.17 11.7 4.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4483) Ashwin PF15323.6 GAN07367.1 - 4.4 7.3 12.0 2.9 7.9 10.3 1.5 2 0 0 2 2 2 0 Developmental protein BLM10_mid PF16507.5 GAN07368.1 - 1.6e-171 571.6 0.1 5.9e-171 569.7 0.1 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GAN07368.1 - 4.5e-33 113.0 3.6 5.7e-32 109.5 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 GAN07368.1 - 0.005 17.1 0.1 0.048 13.9 0.0 2.5 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 GAN07368.1 - 0.017 15.4 0.1 22 5.7 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat CLASP_N PF12348.8 GAN07368.1 - 0.027 14.0 0.1 4.7 6.7 0.0 3.2 2 0 0 2 2 2 0 CLASP N terminal Arc_PepC PF06819.11 GAN07369.1 - 0.053 13.7 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain cobW PF02492.19 GAN07370.1 - 1.4e-41 142.1 0.2 2e-41 141.5 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAN07370.1 - 9.2e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAN07370.1 - 0.0052 16.7 0.2 2.5 8.0 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase MobB PF03205.14 GAN07370.1 - 0.012 15.5 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4315 PF14193.6 GAN07370.1 - 0.012 15.5 0.5 0.045 13.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) tRNA_anti-codon PF01336.25 GAN07370.1 - 0.019 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Pox_A32 PF04665.12 GAN07370.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein SRP54 PF00448.22 GAN07370.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 GAN07370.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Glycogen_syn PF05693.13 GAN07371.1 - 0 1096.6 0.0 0 1096.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 GAN07371.1 - 4.3e-06 26.6 0.1 1.2e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GAN07371.1 - 4.7e-06 26.2 0.0 0.00054 19.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN07371.1 - 5.9e-06 26.7 0.0 0.0062 17.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN07371.1 - 0.00028 20.9 0.1 0.00053 20.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 zf-CCCH_2 PF14608.6 GAN07372.1 - 1.5e-15 57.0 63.5 4.5e-05 23.8 6.1 5.3 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 GAN07372.1 - 0.00044 20.0 3.6 0.00044 20.0 3.6 5.3 5 1 0 5 5 5 1 CCCH-type zinc finger zf-CCCH PF00642.24 GAN07372.1 - 0.01 15.7 1.9 0.01 15.7 1.9 5.7 5 2 1 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAN07372.1 - 0.014 15.5 0.9 0.014 15.5 0.9 5.7 7 0 0 7 7 7 0 Zinc finger domain zf-CCCH_3 PF15663.5 GAN07372.1 - 0.022 15.0 12.8 0.21 11.8 4.2 2.6 2 1 0 2 2 2 0 Zinc-finger containing family Nab2p_Zf1 PF18260.1 GAN07372.1 - 0.25 11.3 0.2 0.25 11.3 0.2 3.5 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Presenilin PF01080.17 GAN07372.1 - 1.1 7.9 3.8 1.7 7.3 3.8 1.3 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 GAN07373.1 - 3.4e-37 128.2 33.8 3.4e-37 128.2 33.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF962 PF06127.11 GAN07373.1 - 1.8 8.7 5.3 2 8.5 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF962) TIMELESS PF04821.14 GAN07375.1 - 2.2e-71 240.4 0.7 2.2e-71 240.4 0.7 2.2 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 GAN07375.1 - 3.2e-08 33.2 0.7 3.2e-08 33.2 0.7 3.2 2 1 1 3 3 3 1 Timeless protein C terminal region Xpo1 PF08389.12 GAN07375.1 - 0.021 14.9 0.3 0.18 11.9 0.0 2.6 2 1 1 3 3 3 0 Exportin 1-like protein XisI PF08869.11 GAN07375.1 - 0.075 13.4 0.3 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 XisI protein CBS PF00571.28 GAN07376.1 - 1e-29 102.8 8.0 7.5e-09 35.9 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 GAN07376.1 - 1.6e-08 34.3 0.6 3.4e-08 33.3 0.6 1.6 1 0 0 1 1 1 1 PB1 domain Pkinase PF00069.25 GAN07377.1 - 8.3e-62 208.9 0.0 1.3e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07377.1 - 3e-31 108.7 0.0 4.5e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAN07377.1 - 1.8e-06 28.6 0.0 6.2e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain PX PF00787.24 GAN07377.1 - 3.6e-05 23.7 0.5 8.4e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 GAN07377.1 - 0.00023 20.6 0.0 0.0022 17.4 0.0 2.1 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAN07377.1 - 0.00091 18.9 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAN07377.1 - 0.0054 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rhomboid_SP PF12595.8 GAN07377.1 - 0.0094 15.3 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Rhomboid serine protease Rad10 PF03834.14 GAN07378.1 - 7.5e-44 148.4 0.1 1.3e-43 147.7 0.1 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 GAN07378.1 - 1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain PTPLA PF04387.14 GAN07378.1 - 0.12 12.1 0.3 4.2 7.1 0.0 2.2 1 1 1 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA CPBP PF02517.16 GAN07379.1 - 4.1e-18 65.5 7.4 4.1e-18 65.5 7.4 2.0 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease KH_1 PF00013.29 GAN07381.1 - 8.4e-44 147.2 9.9 4.8e-17 61.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAN07381.1 - 3.3e-10 39.6 8.6 0.017 15.0 0.1 3.9 3 1 1 4 4 4 3 KH domain KH_4 PF13083.6 GAN07381.1 - 1.7e-09 37.4 1.1 0.055 13.3 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAN07381.1 - 0.00012 22.1 5.2 0.043 13.9 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 GAN07381.1 - 0.015 15.3 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 KH-like RNA-binding domain Mucin PF01456.17 GAN07381.1 - 1.8 8.5 14.6 0.51 10.3 2.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Rhomboid PF01694.22 GAN07382.1 - 2.2e-31 108.9 6.5 2.2e-31 108.9 6.5 2.0 3 0 0 3 3 3 1 Rhomboid family RPE65 PF03055.15 GAN07383.1 - 5.8e-86 289.5 0.1 7.5e-86 289.1 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GPR_Gpa2_C PF11970.8 GAN07384.1 - 0.00043 20.3 1.2 0.013 15.6 0.3 3.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Saf_2TM PF18303.1 GAN07384.1 - 0.0048 16.5 3.9 0.059 12.9 0.1 2.5 2 0 0 2 2 2 1 SAVED-fused 2TM effector domain DUF3231 PF11553.8 GAN07384.1 - 0.11 12.1 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) DUF2140 PF09911.9 GAN07384.1 - 0.51 9.9 4.4 1.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) FixP_N PF14715.6 GAN07384.1 - 3.6 7.4 6.7 20 5.0 0.9 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP CMD PF02627.20 GAN07385.1 - 2.1e-05 24.5 0.0 6.9e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF5072 PF16807.5 GAN07385.1 - 0.02 14.9 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) NTS PF15447.6 GAN07385.1 - 0.22 12.0 1.1 0.93 10.0 0.5 2.3 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 Pkinase PF00069.25 GAN07387.1 - 1.2e-65 221.5 0.4 1.1e-59 201.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07387.1 - 5.5e-39 134.0 0.1 1e-37 129.8 0.1 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAN07387.1 - 2.4e-06 27.1 0.6 5.2e-06 26.0 0.6 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAN07387.1 - 2.5e-06 27.1 0.0 5.4e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAN07387.1 - 2e-05 24.6 0.2 0.00084 19.3 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAN07387.1 - 0.00031 20.4 0.7 0.00064 19.4 0.7 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 GAN07387.1 - 0.0065 15.5 0.8 0.0065 15.5 0.8 2.8 3 0 0 3 3 3 1 Haspin like kinase domain Anillin_N PF16018.5 GAN07387.1 - 0.029 14.9 0.1 0.21 12.2 0.1 2.5 1 0 0 1 1 1 0 Anillin N-terminus Pkinase_fungal PF17667.1 GAN07387.1 - 0.034 12.9 1.4 0.052 12.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 GAN07387.1 - 0.078 12.6 0.1 0.22 11.1 0.1 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 GAN07387.1 - 0.078 12.5 0.4 0.2 11.2 0.4 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Caskin1-CID PF16600.5 GAN07387.1 - 0.4 11.3 3.6 1.9 9.1 3.6 2.2 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain Glyco_transf_20 PF00982.21 GAN07388.1 - 2.6e-163 544.1 0.0 4.6e-163 543.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN07388.1 - 1.6e-55 187.8 0.0 2.6e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 GAN07388.1 - 6.5e-05 22.8 0.0 0.0099 15.6 0.1 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Ldh_1_C PF02866.18 GAN07389.1 - 1.4e-49 168.2 0.0 2.4e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAN07389.1 - 1.3e-45 154.9 0.2 2e-45 154.3 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAN07389.1 - 0.00015 20.9 0.0 0.00047 19.3 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 GAN07389.1 - 0.064 13.4 1.0 0.18 12.0 0.0 2.2 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus CAF1 PF04857.20 GAN07390.1 - 2.3e-22 79.6 1.9 1.6e-11 44.0 0.0 2.8 3 1 0 3 3 3 2 CAF1 family ribonuclease CTP_transf_1 PF01148.20 GAN07391.1 - 8.7e-50 169.9 8.8 6.5e-49 167.1 9.0 1.8 1 1 1 2 2 2 1 Cytidylyltransferase family YpmT PF17431.2 GAN07391.1 - 0.51 10.4 4.1 1 9.5 0.6 2.7 2 0 0 2 2 2 0 Uncharacterized YmpT-like AMP-binding PF00501.28 GAN07392.1 - 4.6e-97 325.3 0.0 5.8e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN07392.1 - 1.7e-22 80.2 0.1 4e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAN07392.1 - 5.7e-18 64.6 0.2 5.7e-18 64.6 0.2 2.8 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus Pkinase PF00069.25 GAN07393.1 - 6.2e-61 206.1 0.1 1.8e-42 145.5 1.1 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07393.1 - 3.5e-28 98.6 1.1 7.3e-26 91.0 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN07393.1 - 0.00034 19.7 0.3 0.0016 17.5 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAN07393.1 - 0.0053 16.7 0.1 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAN07393.1 - 0.1 12.2 0.2 0.48 10.0 0.1 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Na_H_Exchanger PF00999.21 GAN07394.1 - 5.3e-63 213.1 44.8 7.8e-63 212.5 44.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DHHC PF01529.20 GAN07396.1 - 3.7e-38 130.7 10.8 3.7e-38 130.7 10.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Cortexin PF11057.8 GAN07396.1 - 0.13 12.1 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 Cortexin of kidney FYVE PF01363.21 GAN07396.1 - 1.1 9.4 8.8 0.56 10.4 6.2 1.9 2 0 0 2 2 2 0 FYVE zinc finger Pox_A14 PF05767.12 GAN07396.1 - 2.6 8.2 11.0 1.9 8.7 1.5 2.7 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Tim17 PF02466.19 GAN07397.1 - 2.4e-24 85.9 7.8 3.3e-24 85.4 7.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CSD PF00313.22 GAN07399.1 - 5.8e-16 58.1 0.3 1.2e-15 57.1 0.3 1.6 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 GAN07399.1 - 0.13 12.0 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain PH_4 PF15404.6 GAN07400.1 - 6e-14 52.2 9.5 1.7e-09 37.7 3.0 5.2 3 2 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 GAN07400.1 - 7.8e-07 29.6 10.3 0.0034 17.9 0.2 5.3 3 2 1 4 4 4 2 PH domain PH_6 PF15406.6 GAN07400.1 - 0.00073 19.8 0.3 0.2 12.0 0.0 3.4 3 0 0 3 3 3 1 Pleckstrin homology domain KASH_CCD PF14662.6 GAN07401.1 - 0.0097 15.8 15.4 0.074 12.9 0.3 2.6 3 0 0 3 3 3 2 Coiled-coil region of CCDC155 or KASH zf-RVT PF13966.6 GAN07401.1 - 0.031 15.0 0.1 0.085 13.6 0.1 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase TSC22 PF01166.18 GAN07401.1 - 0.19 12.1 4.0 3.2 8.1 0.6 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF2225 PF09986.9 GAN07401.1 - 1.8 8.2 5.3 0.85 9.3 0.2 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DivIC PF04977.15 GAN07401.1 - 6.5 6.6 11.6 1.7 8.5 0.7 2.9 2 0 0 2 2 2 0 Septum formation initiator Nuc_sug_transp PF04142.15 GAN07402.1 - 4.2e-108 361.2 30.3 3.1e-69 233.6 8.9 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 GAN07402.1 - 5.4e-06 26.6 6.7 5.4e-06 26.6 6.7 3.6 3 2 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 GAN07402.1 - 3.4e-05 23.2 16.4 7e-05 22.2 0.8 2.4 2 0 0 2 2 2 2 UAA transporter family DUF3481 PF11980.8 GAN07402.1 - 0.8 9.4 6.8 23 4.8 0.0 3.9 3 1 1 4 4 4 0 C-terminal domain of neuropilin glycoprotein Lipase_3 PF01764.25 GAN07403.1 - 1.8e-16 60.3 0.0 3.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF4578 PF15147.6 GAN07403.1 - 0.025 15.5 4.0 0.071 14.0 4.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Abhydrolase_5 PF12695.7 GAN07403.1 - 0.056 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SUIM_assoc PF16619.5 GAN07403.1 - 8.3 6.6 13.6 21 5.3 7.6 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_lid_2 PF17863.1 GAN07404.1 - 0.00039 20.2 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain Gemini_coat PF00844.18 GAN07404.1 - 0.049 13.1 0.7 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family AAA_5 PF07728.14 GAN07404.1 - 0.05 13.6 0.2 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAN07404.1 - 0.085 12.7 0.1 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAXNEB PF05625.11 GAN07405.1 - 1.9e-94 316.8 0.0 2.8e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein Synaptobrevin PF00957.21 GAN07405.1 - 1.1e-31 108.4 0.6 2.4e-31 107.4 0.6 1.6 1 0 0 1 1 1 1 Synaptobrevin Glyco_transf_34 PF05637.12 GAN07405.1 - 1.1e-17 64.6 1.3 5e-15 55.9 1.3 2.3 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GAN07405.1 - 3.4e-11 43.1 0.0 6.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF273 ATPase PF06745.13 GAN07405.1 - 0.00011 21.6 0.0 0.00037 19.9 0.0 1.9 2 0 0 2 2 2 1 KaiC Inp1 PF12634.7 GAN07405.1 - 0.028 14.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 Clathrin_H_link PF13838.6 GAN07405.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Clathrin-H-link RabGAP-TBC PF00566.18 GAN07406.1 - 1.7e-36 125.9 1.6 2.4e-36 125.4 1.6 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 GAN07407.1 - 0.0063 16.4 1.1 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN07407.1 - 0.06 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain Acetyltransf_1 PF00583.25 GAN07408.1 - 1e-14 54.7 0.0 1.3e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN07408.1 - 2.2e-09 37.3 0.1 2.7e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN07408.1 - 2.3e-09 37.5 0.1 3e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN07408.1 - 3e-06 27.1 0.0 4.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAN07408.1 - 0.0038 17.4 0.2 0.005 17.0 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NPR3 PF03666.13 GAN07408.1 - 0.028 13.2 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pho86 PF11124.8 GAN07408.1 - 0.037 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_CG PF14542.6 GAN07408.1 - 0.089 12.9 0.0 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FKBP_C PF00254.28 GAN07409.1 - 8.1e-09 35.7 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ins134_P3_kin PF05770.11 GAN07410.1 - 2.6e-27 95.6 0.2 4.5e-27 94.9 0.2 1.3 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 GAN07410.1 - 7.8e-16 58.2 0.1 1.6e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Flavodoxin_3 PF12641.7 GAN07410.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain ATP-grasp PF02222.22 GAN07410.1 - 0.025 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_S4e PF00900.20 GAN07411.1 - 8.4e-38 128.1 1.1 1.9e-36 123.8 0.4 2.3 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 GAN07411.1 - 1.1e-25 89.0 0.2 3.5e-25 87.4 0.1 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 GAN07411.1 - 3.5e-19 68.6 7.4 1.2e-18 67.0 7.9 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 GAN07411.1 - 4.2e-07 29.6 0.0 8.7e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 GAN07411.1 - 0.00014 21.7 8.4 0.00057 19.7 6.5 3.0 3 1 0 3 3 3 1 KOW motif Shisa PF13908.6 GAN07412.1 - 5.6e-05 23.5 2.3 6.2e-05 23.3 1.1 1.7 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 GAN07412.1 - 0.0041 16.9 0.6 0.0067 16.2 0.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SARAF PF06682.12 GAN07412.1 - 0.016 14.9 0.1 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Aldedh PF00171.22 GAN07413.1 - 1.8e-136 455.3 0.0 2.1e-136 455.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LZ3wCH PF18517.1 GAN07413.1 - 0.038 14.1 0.3 0.1 12.7 0.3 1.7 1 0 0 1 1 1 0 Leucine zipper with capping helix domain LuxC PF05893.14 GAN07413.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) VHS PF00790.19 GAN07414.1 - 3.6e-30 104.7 5.0 4.3e-24 85.0 0.0 3.6 2 2 2 4 4 4 2 VHS domain Alpha_adaptinC2 PF02883.20 GAN07414.1 - 6.4e-19 68.3 0.0 6.4e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 GAN07414.1 - 1.2e-09 38.3 2.0 1.2e-09 38.3 2.0 2.5 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 GAN07414.1 - 5.8e-06 25.8 2.1 1e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 GGA N-GAT domain DUF2407_C PF13373.6 GAN07415.1 - 1.9e-25 89.7 8.6 1.6e-24 86.7 8.6 2.4 1 1 0 1 1 1 1 DUF2407 C-terminal domain Steroid_dh PF02544.16 GAN07415.1 - 4.3e-16 59.2 2.1 4.3e-16 59.2 2.1 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 GAN07415.1 - 8.2e-12 44.7 0.1 1.8e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAN07415.1 - 8.5e-10 39.1 0.1 1.7e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 GAN07415.1 - 1.8e-05 24.4 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 GAN07415.1 - 3.4e-05 23.9 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAN07415.1 - 0.032 14.6 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF4203 PF13886.6 GAN07415.1 - 8 6.1 9.7 1.1 8.8 1.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4203) Ribosomal_S19 PF00203.21 GAN07416.1 - 7.5e-26 89.8 0.0 8.6e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 AMP-binding PF00501.28 GAN07417.1 - 6.9e-71 239.1 0.0 9.6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAN07417.1 - 5.6e-68 228.9 0.0 8e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAN07417.1 - 7.7e-13 48.6 0.2 2.7e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 GAN07417.1 - 9e-11 41.1 0.1 2.6e-09 36.3 0.1 2.1 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 GAN07417.1 - 8.2e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN07417.1 - 3.8e-08 32.7 0.0 6.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 GAN07417.1 - 1.2e-05 26.2 0.0 5.1e-05 24.2 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 GAN07417.1 - 0.00035 20.5 0.0 0.003 17.5 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAN07417.1 - 0.0028 17.1 0.0 0.0059 16.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Kei1 PF08552.11 GAN07418.1 - 1.8e-22 80.2 19.5 5.2e-18 65.6 11.2 2.0 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 DUF2070 PF09843.9 GAN07418.1 - 6.1 5.0 8.1 8.4 4.6 8.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Nexin_C PF08628.12 GAN07419.1 - 3.1e-21 76.0 2.9 1.9e-20 73.5 1.1 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PXA PF02194.15 GAN07419.1 - 9.8e-21 74.5 1.5 9.8e-21 74.5 1.5 2.3 2 1 0 2 2 2 1 PXA domain PX PF00787.24 GAN07419.1 - 0.00039 20.4 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 PX domain DUF4487 PF14868.6 GAN07419.1 - 0.36 9.6 5.4 0.055 12.3 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) CAP PF00188.26 GAN07420.1 - 9.1e-20 71.8 4.8 9.1e-20 71.8 4.8 1.7 1 1 0 2 2 2 1 Cysteine-rich secretory protein family HMGL-like PF00682.19 GAN07421.1 - 2.6e-63 214.1 2.4 5.8e-59 199.8 0.5 2.7 2 1 1 3 3 3 2 HMGL-like PX PF00787.24 GAN07422.1 - 1e-18 67.4 0.1 2.9e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 PX domain Porin_7 PF16956.5 GAN07422.1 - 0.11 12.1 2.9 0.11 12.2 1.3 1.7 2 0 0 2 2 2 0 Putative general bacterial porin DRY_EERY PF09750.9 GAN07422.1 - 4 7.7 7.2 0.64 10.3 2.2 2.0 2 0 0 2 2 2 0 Alternative splicing regulator PCNA_N PF00705.18 GAN07423.1 - 1.4e-53 179.9 4.6 1.7e-53 179.7 2.4 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 GAN07423.1 - 1.9e-51 173.6 0.2 2.7e-51 173.0 0.2 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 GAN07423.1 - 4.6e-09 36.1 0.1 5.9e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 GAN07423.1 - 2e-08 33.7 1.2 8.9e-07 28.2 1.2 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 GAN07423.1 - 0.00035 19.8 0.1 0.00098 18.3 0.0 1.8 1 1 1 2 2 2 1 Hus1-like protein Arrestin_C PF02752.22 GAN07424.1 - 5.8e-14 52.7 0.2 1.9e-13 51.0 0.1 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN07424.1 - 2.7e-05 24.2 0.0 0.00067 19.7 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 GAN07425.1 - 6.9e-68 228.9 0.0 8.1e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07425.1 - 1.1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN07425.1 - 3.4e-06 26.6 0.0 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAN07425.1 - 0.0093 14.9 0.1 0.029 13.3 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAN07425.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GAN07425.1 - 0.075 12.9 0.1 0.25 11.3 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAN07425.1 - 0.089 12.4 0.2 0.79 9.3 0.2 2.0 1 1 0 1 1 1 0 RIO1 family FPN1 PF06963.12 GAN07427.1 - 7.5e-100 334.5 19.5 9.9e-100 334.1 19.5 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) UCR_Fe-S_N PF10399.9 GAN07427.1 - 0.026 13.9 0.2 0.081 12.3 0.2 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Kinesin PF00225.23 GAN07428.1 - 8.7e-95 317.4 0.1 1.2e-94 316.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAN07428.1 - 1.3e-17 64.2 0.1 4.1e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding SAM_2 PF07647.17 GAN07428.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN07428.1 - 0.0033 17.8 0.1 0.0072 16.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DEAD PF00270.29 GAN07428.1 - 0.48 10.2 3.9 9.3 6.0 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase Exo_endo_phos PF03372.23 GAN07429.1 - 1.2e-16 61.0 0.0 1.8e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cyt_c_ox_IV PF12270.8 GAN07429.1 - 0.29 11.3 1.7 0.56 10.3 1.7 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV VirB3 PF05101.13 GAN07429.1 - 0.9 9.8 3.9 4.5 7.6 3.9 2.1 1 1 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DPBB_1 PF03330.18 GAN07430.1 - 8.6e-11 42.0 0.3 1.4e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN07430.1 - 6.5e-07 29.2 0.6 8.3e-07 28.9 0.6 1.2 1 0 0 1 1 1 1 Barwin family DUF871 PF05913.11 GAN07430.1 - 0.052 12.7 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Glutaredoxin PF00462.24 GAN07431.1 - 8.7e-24 83.5 0.1 1.1e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 GAN07431.1 - 8.7e-06 26.1 0.0 1e-05 25.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN07431.1 - 0.0014 18.9 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 GAN07431.1 - 0.0049 17.3 0.2 0.015 15.7 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 GAN07431.1 - 0.0099 15.7 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 1 DSBA-like thioredoxin domain TraF PF13728.6 GAN07431.1 - 0.024 14.5 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Filamin PF00630.19 GAN07431.1 - 0.029 15.2 0.2 0.034 15.0 0.2 1.1 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF4258 PF14076.6 GAN07431.1 - 0.05 14.0 0.1 0.068 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) DUF2847 PF11009.8 GAN07431.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) NIF PF03031.18 GAN07431.1 - 0.12 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DUF3808 PF10300.9 GAN07432.1 - 6.2e-52 176.9 1.7 1.6e-49 169.0 0.8 3.3 1 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_12 PF13424.6 GAN07432.1 - 0.07 13.4 0.2 8.3 6.8 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN07432.1 - 0.085 13.0 0.0 43 4.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 GAN07433.1 - 1.9e-37 129.1 0.0 2.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN07433.1 - 5.5e-10 39.7 1.0 6.1e-05 23.5 0.0 3.0 3 1 1 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN07433.1 - 1.3e-09 38.1 0.0 0.003 17.2 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAN07433.1 - 1.2e-08 34.6 1.0 6.5e-06 25.6 1.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN07433.1 - 3.5e-07 30.3 0.1 0.21 11.6 0.0 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 GAN07433.1 - 8.2e-07 28.1 1.5 0.00057 18.7 0.1 2.7 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 GAN07433.1 - 6.6e-06 25.4 0.1 0.042 12.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAN07433.1 - 3.3e-05 24.0 0.1 0.013 15.7 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAN07433.1 - 0.0003 20.1 0.0 0.59 9.3 0.0 2.5 2 0 0 2 2 2 2 Thi4 family Trp_halogenase PF04820.14 GAN07433.1 - 0.00042 19.3 0.1 0.038 12.9 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase ThiF PF00899.21 GAN07433.1 - 0.00051 19.5 0.0 0.85 8.9 0.0 2.3 2 0 0 2 2 2 2 ThiF family Sacchrp_dh_NADP PF03435.18 GAN07433.1 - 0.00056 20.2 0.4 0.076 13.3 0.0 2.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAN07433.1 - 0.0018 18.6 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain AlaDh_PNT_C PF01262.21 GAN07433.1 - 0.0069 15.7 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAN07433.1 - 0.0072 15.4 0.0 1.9 7.5 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAN07433.1 - 0.0086 16.0 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAN07433.1 - 0.014 15.0 1.1 0.22 11.1 0.2 2.5 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 GAN07433.1 - 0.019 14.1 0.0 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Ldh_1_N PF00056.23 GAN07433.1 - 0.02 15.0 0.4 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 GAN07433.1 - 0.059 12.4 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain MTS PF05175.14 GAN07433.1 - 0.097 12.2 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain zf-RVT PF13966.6 GAN07434.1 - 9.7e-09 35.8 5.3 3.6e-08 34.0 5.3 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Aldedh PF00171.22 GAN07435.1 - 1.1e-95 320.9 0.0 1.4e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Inv-AAD PF18785.1 GAN07436.1 - 1.4e-30 105.8 1.1 5.4e-30 103.9 1.1 1.8 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 GAN07436.1 - 4.7e-22 77.8 0.2 6.4e-22 77.3 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAN07436.1 - 2.2e-09 37.2 0.1 2.7e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 GAN07436.1 - 0.00053 19.9 0.0 0.0026 17.7 0.0 1.9 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 GAN07436.1 - 0.0056 16.8 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 APOBEC3 RPE65 PF03055.15 GAN07437.1 - 1.3e-92 311.4 0.0 1.6e-92 311.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MFS_1 PF07690.16 GAN07438.1 - 4.9e-28 98.1 51.4 1.3e-26 93.4 36.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN07438.1 - 0.0026 16.4 13.3 0.0026 16.4 13.3 3.2 1 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 GAN07438.1 - 0.033 13.1 28.9 0.092 11.6 4.0 3.0 1 1 2 3 3 3 0 MFS_1 like family Sugar_tr PF00083.24 GAN07439.1 - 2.6e-102 343.0 31.8 5.8e-53 180.4 6.6 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN07439.1 - 3.2e-24 85.5 28.2 3.2e-24 85.5 28.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Kinocilin PF15033.6 GAN07439.1 - 0.037 13.7 0.6 0.22 11.2 0.5 2.2 2 0 0 2 2 2 0 Kinocilin protein zf-C2H2 PF00096.26 GAN07440.1 - 8.4e-12 44.9 21.2 2e-05 24.8 0.4 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN07440.1 - 1.9e-08 34.4 18.1 1.4e-05 25.3 2.2 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN07440.1 - 1.3e-05 25.6 19.8 0.0098 16.7 0.4 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf_ZIC PF18366.1 GAN07440.1 - 2.2e-05 24.4 4.1 0.0011 19.1 0.0 3.7 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 GAN07440.1 - 0.0014 18.9 7.6 1.8 8.9 6.0 2.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAN07440.1 - 0.008 16.8 0.9 0.008 16.8 0.9 5.8 3 3 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 GAN07440.1 - 1.3 9.4 0.1 1.3 9.4 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Alginate_lyase PF05426.12 GAN07441.1 - 2.6e-16 60.0 0.0 4e-15 56.1 0.0 2.4 1 1 0 1 1 1 1 Alginate lyase Suppressor_APC PF11414.8 GAN07441.1 - 0.39 10.8 5.1 0.13 12.3 1.5 2.1 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Creatinase_N_2 PF16189.5 GAN07442.1 - 7.9e-50 169.1 0.0 1.1e-48 165.4 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GAN07442.1 - 5.1e-44 150.5 0.1 1e-43 149.5 0.1 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 GAN07442.1 - 3.2e-20 71.9 0.1 2.1e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAN07442.1 - 5.7e-16 59.4 0.0 1.9e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain PP-binding PF00550.25 GAN07443.1 - 1.7e-13 50.7 0.3 2.3e-13 50.3 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAN07443.1 - 4.9e-06 26.7 2.0 1e-05 25.7 1.7 1.6 1 1 1 2 2 2 1 Acyl-carrier Ribosomal_L50 PF10501.9 GAN07443.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S Peptidase_C54 PF03416.19 GAN07444.1 - 1.5e-102 342.8 0.0 2e-102 342.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Mpp10 PF04006.12 GAN07445.1 - 0.48 8.8 21.7 0.015 13.8 13.0 2.0 2 0 0 2 2 2 0 Mpp10 protein dCMP_cyt_deam_1 PF00383.23 GAN07446.1 - 1.5e-10 40.9 0.0 2.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAN07446.1 - 2.8e-10 40.1 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 GAN07446.1 - 0.0022 18.1 0.1 0.007 16.5 0.1 1.9 2 0 0 2 2 2 1 Xanthomonas XOO_2897-like deaminase SNAD4 PF18750.1 GAN07446.1 - 0.0066 16.6 0.8 0.012 15.8 0.8 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 GAN07446.1 - 0.01 15.9 0.5 0.013 15.6 0.5 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 GAN07446.1 - 0.04 14.0 0.1 0.053 13.6 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 G-alpha PF00503.20 GAN07447.1 - 7.7e-121 403.6 6.3 8.9e-121 403.4 6.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN07447.1 - 2.4e-14 53.2 0.8 5e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN07447.1 - 0.00075 18.9 3.2 0.034 13.5 0.1 2.9 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 GAN07447.1 - 0.0065 16.3 0.1 0.05 13.4 0.0 2.2 2 0 0 2 2 2 1 CHC2 zinc finger GTP_EFTU PF00009.27 GAN07447.1 - 0.012 15.1 0.1 0.42 10.1 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 GAN07447.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 GAN07447.1 - 0.038 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 GAN07447.1 - 0.043 14.0 0.4 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAN07447.1 - 0.046 13.8 0.1 7.2 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 GAN07447.1 - 0.42 10.5 3.0 1.6 8.6 0.1 2.4 2 1 0 2 2 2 0 Rad17 P-loop domain RNA_pol_Rpb2_6 PF00562.28 GAN07448.1 - 1.8e-122 409.2 0.7 2.2e-122 408.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAN07448.1 - 8.8e-60 201.7 0.4 1.3e-59 201.1 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 GAN07448.1 - 4.5e-35 119.9 0.6 2.1e-34 117.8 0.6 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAN07448.1 - 2e-33 115.6 3.4 5.7e-33 114.1 3.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 GAN07448.1 - 1.6e-22 79.5 3.1 3.7e-22 78.4 2.5 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 GAN07448.1 - 2.6e-21 75.6 0.1 9.6e-21 73.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 GAN07448.1 - 8.9e-10 39.0 1.4 2.8e-09 37.4 1.4 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Inhibitor_I9 PF05922.16 GAN07449.1 - 1e-06 29.3 0.1 1.3e-06 29.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3808 PF10300.9 GAN07451.1 - 4.6e-70 236.7 1.9 4.6e-70 236.7 1.9 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 GAN07451.1 - 0.00067 19.6 1.1 0.71 10.1 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07451.1 - 0.069 14.0 0.0 44 5.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN07451.1 - 3 8.7 4.6 2e+02 2.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DDHD PF02862.17 GAN07451.1 - 6.9 6.8 9.1 11 6.1 6.6 2.3 2 0 0 2 2 2 0 DDHD domain Aa_trans PF01490.18 GAN07452.1 - 8.4e-78 261.9 36.2 9.8e-78 261.7 36.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ICL PF00463.21 GAN07454.1 - 1.1e-263 875.5 1.4 1.2e-263 875.4 1.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAN07454.1 - 2.1e-08 33.9 0.0 4.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase M16C_assoc PF08367.11 GAN07455.1 - 8.8e-81 270.7 1.6 1.4e-80 270.1 0.3 2.0 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GAN07455.1 - 2.1e-31 109.4 0.1 3.1e-23 82.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAN07455.1 - 2.2e-09 37.4 0.1 1.4e-06 28.4 0.0 3.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) BORCS6 PF10157.9 GAN07455.1 - 0.0096 16.2 0.6 0.038 14.2 0.0 2.2 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 6 NETI PF14044.6 GAN07455.1 - 0.02 14.6 0.0 0.068 12.9 0.0 1.8 1 0 0 1 1 1 0 NETI protein DUF2312 PF10073.9 GAN07455.1 - 0.26 11.0 7.4 1.2 8.8 0.2 3.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) SF1-HH PF16275.5 GAN07457.1 - 3.5e-38 130.4 3.7 9.7e-38 129.0 3.7 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 GAN07457.1 - 2.5e-09 36.8 9.5 2.9e-05 23.9 1.0 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 GAN07457.1 - 1.9e-08 34.0 0.3 3.8e-08 33.1 0.3 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 GAN07457.1 - 0.014 15.4 8.4 0.061 13.3 1.3 2.9 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 GAN07457.1 - 0.056 13.3 9.8 0.13 12.2 0.6 2.8 1 1 1 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 GAN07457.1 - 0.06 13.7 4.6 0.13 12.7 4.6 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_4 PF14392.6 GAN07457.1 - 0.063 13.0 7.8 1.9 8.3 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 GAN07457.1 - 0.065 13.3 4.3 0.14 12.3 4.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-CCHC_2 PF13696.6 GAN07457.1 - 0.77 9.6 9.2 0.82 9.5 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle CCDC-167 PF15188.6 GAN07457.1 - 7.1 7.1 6.3 11 6.5 0.5 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 E1-E2_ATPase PF00122.20 GAN07458.1 - 6.3e-50 169.2 12.0 1.2e-49 168.3 4.2 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN07458.1 - 4.8e-38 130.7 0.6 4.8e-38 130.7 0.6 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAN07458.1 - 4e-21 74.9 0.0 9.3e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN07458.1 - 9.4e-17 60.5 2.8 1.1e-16 60.3 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 GAN07458.1 - 4.1e-16 59.9 0.5 6.6e-13 49.4 0.1 4.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN07458.1 - 0.0028 17.4 0.7 0.0028 17.4 0.7 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4133 PF13571.6 GAN07458.1 - 0.041 14.2 0.6 0.041 14.2 0.6 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4133) UIM PF02809.20 GAN07459.1 - 0.0099 15.7 0.6 5.7 7.1 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif Rubis-subs-bind PF09273.11 GAN07459.1 - 0.083 13.6 0.6 0.19 12.4 0.6 1.6 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding Bromodomain PF00439.25 GAN07460.1 - 8.2e-48 160.4 3.4 3.1e-23 81.7 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 GAN07460.1 - 5e-21 74.6 0.2 5e-21 74.6 0.2 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation MnmE_helical PF12631.7 GAN07460.1 - 0.00041 20.6 3.1 0.00072 19.8 3.1 1.3 1 0 0 1 1 1 1 MnmE helical domain PKcGMP_CC PF16808.5 GAN07460.1 - 0.013 15.3 2.6 1.1 9.2 0.2 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SRP-alpha_N PF04086.13 GAN07460.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.1 2 1 1 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal GreA_GreB_N PF03449.15 GAN07460.1 - 0.22 11.7 8.7 20 5.4 0.3 3.8 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal DUF4140 PF13600.6 GAN07460.1 - 0.23 11.9 6.4 0.56 10.7 2.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2802 PF10975.8 GAN07460.1 - 0.8 9.9 3.2 6.7 6.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) DUF3450 PF11932.8 GAN07460.1 - 2 7.6 8.7 0.41 9.9 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ABC_tran_CTD PF16326.5 GAN07460.1 - 2.1 8.7 7.0 21 5.5 2.7 3.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Csm1_N PF18504.1 GAN07460.1 - 2.2 8.7 7.3 2.8 8.3 2.0 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 GAN07460.1 - 5.6 7.9 9.9 25 5.8 0.4 3.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain WD40 PF00400.32 GAN07461.1 - 5.1e-41 137.9 27.1 1.5e-06 28.8 0.4 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 GAN07461.1 - 7.5e-11 41.4 8.6 0.64 8.6 0.0 6.1 2 2 4 6 6 6 6 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN07461.1 - 1.1e-10 41.7 2.1 0.062 13.6 0.0 5.3 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAN07461.1 - 1.8e-07 30.9 2.2 3.3e-07 30.1 2.2 1.5 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 GAN07461.1 - 4.9e-06 26.1 0.2 1.6e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 WD40-like domain F-box PF00646.33 GAN07461.1 - 9.7e-05 22.1 0.4 0.00022 21.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 GAN07461.1 - 0.0008 19.4 0.1 5.3 7.1 0.0 4.3 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 GAN07461.1 - 0.0011 18.6 0.0 0.0062 16.1 0.0 2.0 1 1 1 2 2 2 1 PQQ-like domain DUF5046 PF16465.5 GAN07461.1 - 0.013 15.0 0.0 0.49 9.8 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) F-box-like_2 PF13013.6 GAN07461.1 - 0.053 13.5 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 F-box-like domain Spc24 PF08286.11 GAN07462.1 - 1e-07 32.1 0.0 1.1e-07 32.0 0.0 1.0 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 Pkinase PF00069.25 GAN07463.1 - 8.7e-76 254.8 0.0 1.2e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07463.1 - 2.6e-37 128.5 0.0 4.1e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 GAN07463.1 - 5.8e-22 78.3 0.0 8.7e-18 64.9 0.0 2.7 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 GAN07463.1 - 2.6e-08 33.6 0.0 4.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 GAN07463.1 - 1.9e-06 27.9 0.1 4.7e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) KA1 PF02149.19 GAN07463.1 - 0.0012 18.6 0.0 0.033 14.0 0.0 2.6 2 0 0 2 2 2 1 Kinase associated domain 1 RIO1 PF01163.22 GAN07463.1 - 0.0017 18.0 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 GAN07463.1 - 0.0033 16.4 0.1 0.0074 15.3 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 GAN07463.1 - 0.015 14.2 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 GAN07463.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN07463.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ECH_2 PF16113.5 GAN07464.1 - 2.7e-12 46.8 0.0 1.1e-10 41.5 0.0 2.5 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase DUF4937 PF16291.5 GAN07464.1 - 0.26 11.6 2.8 1.6 9.0 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 PK PF00224.21 GAN07465.1 - 6.5e-167 554.7 4.4 8.1e-167 554.4 4.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAN07465.1 - 2e-36 124.8 0.0 6.4e-36 123.1 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAN07465.1 - 1.1e-05 24.6 0.2 2.7e-05 23.4 0.2 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Ribosomal_L36e PF01158.18 GAN07467.1 - 1.1e-37 128.1 4.8 1.3e-37 127.9 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e End3 PF12761.7 GAN07468.1 - 6.1e-43 147.3 4.9 9.2e-43 146.7 4.9 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 GAN07468.1 - 1.9e-35 121.0 0.0 2.3e-30 104.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 GAN07468.1 - 1.6e-07 31.7 0.3 0.0017 18.7 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAN07468.1 - 6.8e-07 28.4 0.1 1.6e-05 24.1 0.2 2.4 2 0 0 2 2 2 1 EF hand DUF1720 PF08226.11 GAN07468.1 - 0.00058 20.2 41.7 0.0019 18.5 41.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1720) EF-hand_6 PF13405.6 GAN07468.1 - 0.00085 19.1 4.0 0.2 11.7 0.4 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 GAN07468.1 - 0.0013 18.6 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Laminin_II PF06009.12 GAN07468.1 - 0.07 13.1 10.8 0.096 12.7 1.6 2.2 1 1 1 2 2 2 0 Laminin Domain II CytochromB561_N PF09786.9 GAN07468.1 - 0.13 11.2 1.1 0.18 10.8 1.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Fib_alpha PF08702.10 GAN07468.1 - 0.78 9.9 6.4 1.3 9.2 5.8 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 GAN07468.1 - 1.4 7.7 16.0 0.66 8.8 4.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 GAN07468.1 - 1.4 9.6 10.5 5.9 7.6 0.8 2.6 2 0 0 2 2 2 0 SlyX Csm1_N PF18504.1 GAN07468.1 - 1.8 9.0 8.8 0.087 13.2 1.4 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF2203 PF09969.9 GAN07468.1 - 3.1 8.6 6.5 5 7.9 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YscO PF07321.12 GAN07468.1 - 7.2 6.5 22.3 1.7 8.6 9.8 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO PINIT PF14324.6 GAN07469.1 - 4.2e-30 105.0 0.4 9.1e-30 103.9 0.4 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 GAN07469.1 - 6.8e-20 70.6 1.0 1.2e-19 69.7 1.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GAN07469.1 - 2.1e-09 37.0 1.0 5.1e-09 35.8 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAN07469.1 - 0.035 14.0 0.3 0.091 12.6 0.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1133 PF06576.11 GAN07469.1 - 0.043 13.2 0.1 0.53 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) zf-C2H2_9 PF16293.5 GAN07469.1 - 0.12 12.2 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C3HC4_2 PF13923.6 GAN07469.1 - 0.39 10.6 2.1 1.6 8.6 2.4 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.14 GAN07469.1 - 0.4 8.9 3.5 0.6 8.3 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Sin3a_C PF16879.5 GAN07470.1 - 7.6e-70 235.9 6.9 9.2e-69 232.3 6.2 2.8 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 GAN07470.1 - 9.5e-45 150.5 9.3 2.5e-17 62.7 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAN07470.1 - 1.6e-38 130.7 0.5 5.5e-38 129.0 0.5 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor BPTA PF17044.5 GAN07470.1 - 0.025 14.4 0.4 0.06 13.2 0.4 1.5 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A DUF202 PF02656.15 GAN07471.1 - 2.2e-14 53.6 4.8 2.2e-14 53.6 4.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Glycos_transf_3 PF00591.21 GAN07472.1 - 3e-85 285.8 1.2 4.1e-85 285.4 1.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 GAN07472.1 - 9.8e-17 60.6 0.0 2.1e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain NTP_transferase PF00483.23 GAN07474.1 - 2.9e-55 187.5 0.0 4.5e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAN07474.1 - 9.3e-13 47.4 5.0 5.2e-10 38.6 2.3 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAN07474.1 - 5.2e-10 39.9 0.0 7.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 GAN07474.1 - 0.00016 21.3 2.1 0.00016 21.3 2.1 2.8 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 GAN07474.1 - 0.014 13.6 0.2 0.021 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) SRP54 PF00448.22 GAN07474.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Fucokinase PF07959.12 GAN07474.1 - 0.1 11.5 0.1 0.33 9.9 0.0 1.8 2 1 0 2 2 2 0 L-fucokinase DUF2810 PF10928.8 GAN07474.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Pkinase PF00069.25 GAN07475.1 - 3e-69 233.3 0.0 3.8e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07475.1 - 1.9e-39 135.6 0.0 2.5e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN07475.1 - 9.5e-07 28.4 0.0 2e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAN07475.1 - 1.4e-05 24.6 0.0 3.2e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN07475.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 GAN07475.1 - 0.026 14.1 0.0 0.29 10.7 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4203 PF13886.6 GAN07476.1 - 6.7e-36 123.8 30.4 1.3e-35 122.9 30.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) HEAT PF02985.22 GAN07476.1 - 6e-08 32.3 0.0 0.057 13.7 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.25 GAN07476.1 - 2.2e-05 24.0 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 GAN07476.1 - 0.00029 20.9 0.1 0.0019 18.2 0.1 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAN07476.1 - 0.0057 17.1 0.4 4.3 7.9 0.0 3.6 3 0 0 3 3 3 1 HEAT-like repeat Kinase-like PF14531.6 GAN07476.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HEAT_2 PF13646.6 GAN07476.1 - 0.022 15.1 0.1 0.13 12.6 0.0 2.5 2 1 0 2 2 2 0 HEAT repeats Adaptin_N PF01602.20 GAN07476.1 - 0.026 13.1 0.1 0.16 10.5 0.0 1.8 1 1 1 2 2 2 0 Adaptin N terminal region Vir_act_alpha_C PF10400.9 GAN07476.1 - 0.13 13.0 0.4 0.3 11.8 0.4 1.5 1 0 0 1 1 1 0 Virulence activator alpha C-term PUF PF00806.19 GAN07477.1 - 5.8e-45 148.5 7.1 4e-06 26.2 0.0 8.8 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF5407 PF17401.2 GAN07477.1 - 0.13 12.5 2.6 1.1 9.6 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5407) MitMem_reg PF13012.6 GAN07478.1 - 4e-27 94.9 1.6 6.7e-27 94.1 0.5 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAN07478.1 - 2e-14 53.6 0.0 4.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 GAN07478.1 - 0.038 14.0 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) FAR1 PF03101.15 GAN07479.1 - 2.9e-05 24.7 0.7 2.9e-05 24.7 0.7 2.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain PsiB PF06290.11 GAN07479.1 - 0.026 14.0 0.1 0.071 12.6 0.0 1.7 2 0 0 2 2 2 0 Plasmid SOS inhibition protein (PsiB) DUF2205 PF10224.9 GAN07480.1 - 6e-14 51.8 0.5 8.2e-14 51.4 0.5 1.2 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 GAN07480.1 - 0.0048 17.1 4.2 1.5 9.1 1.0 2.4 2 0 0 2 2 2 2 Homeobox associated leucine zipper CENP-H PF05837.12 GAN07480.1 - 0.011 16.1 1.3 0.012 16.0 1.3 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3135 PF11333.8 GAN07480.1 - 0.011 15.9 0.2 0.013 15.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) YabA PF06156.13 GAN07480.1 - 0.012 16.2 1.2 0.018 15.7 1.2 1.3 1 1 0 1 1 1 0 Initiation control protein YabA Sas10_Utp3 PF04000.15 GAN07480.1 - 0.014 16.0 0.3 0.019 15.6 0.3 1.3 1 0 0 1 1 1 0 Sas10/Utp3/C1D family ArAE_2_N PF10337.9 GAN07481.1 - 1e-20 74.2 23.2 2.4e-14 53.2 0.0 4.3 3 1 1 4 4 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAN07481.1 - 1.1e-19 70.8 36.1 2.6e-18 66.4 18.0 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.12 GAN07481.1 - 3.2e-15 55.7 14.2 3.2e-15 55.7 14.2 3.1 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 GAN07481.1 - 1.1e-13 50.9 4.4 1.1e-13 50.9 4.4 4.1 4 2 0 4 4 4 1 Aluminium activated malate transporter ArAE_2 PF10334.9 GAN07481.1 - 2.3e-13 50.5 0.1 6.5e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 GAN07481.1 - 0.0022 17.1 2.1 0.006 15.7 2.1 1.8 1 1 0 1 1 1 1 FUSC-like inner membrane protein yccS ArAE_1 PF06081.11 GAN07481.1 - 0.0036 17.4 6.3 0.0036 17.4 6.3 3.3 3 0 0 3 3 3 1 Aromatic acid exporter family member 1 C-C_Bond_Lyase PF15617.6 GAN07481.1 - 0.0054 15.9 0.4 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold Vpu PF00558.19 GAN07481.1 - 0.055 13.2 1.8 1.9 8.3 0.3 3.5 3 0 0 3 3 3 0 Vpu protein PriCT_1 PF08708.11 GAN07481.1 - 0.1 12.3 0.1 4 7.3 0.0 3.0 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) Blt1 PF12754.7 GAN07481.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Blt1 N-terminal domain MASE2 PF05230.11 GAN07481.1 - 3.9 7.6 11.0 3.8 7.6 0.1 3.6 4 0 0 4 4 4 0 MASE2 domain AAA PF00004.29 GAN07482.1 - 4.3e-41 140.4 0.0 9.7e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAN07482.1 - 1.1e-19 70.1 0.1 2.1e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAN07482.1 - 2e-09 37.1 0.2 6.3e-09 35.5 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAN07482.1 - 1.4e-05 25.1 0.1 8.3e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN07482.1 - 1.9e-05 25.1 0.2 0.0059 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAN07482.1 - 0.00019 21.2 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAN07482.1 - 0.00039 20.6 0.0 0.0028 17.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAN07482.1 - 0.00044 20.5 0.3 0.06 13.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GAN07482.1 - 0.0015 17.7 0.0 0.0032 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 GAN07482.1 - 0.0016 17.9 0.1 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 GAN07482.1 - 0.0045 16.4 0.1 0.016 14.6 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 GAN07482.1 - 0.0053 16.6 0.1 0.37 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAN07482.1 - 0.0056 16.8 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 GAN07482.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 GAN07482.1 - 0.04 13.2 0.3 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 GAN07482.1 - 0.045 14.3 0.1 0.34 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAN07482.1 - 0.048 13.7 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 GAN07482.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAN07482.1 - 0.059 13.1 0.2 0.24 11.1 0.1 2.2 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 GAN07482.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 GAN07482.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DivIC PF04977.15 GAN07482.1 - 0.58 10.0 3.3 1.5 8.6 2.6 2.1 1 1 0 1 1 1 0 Septum formation initiator AAA_25 PF13481.6 GAN07482.1 - 0.72 9.4 2.5 1.8 8.1 0.1 2.6 2 1 1 3 3 3 0 AAA domain FlxA PF14282.6 GAN07482.1 - 1.2 9.2 6.3 0.27 11.2 2.2 2.0 3 0 0 3 3 2 0 FlxA-like protein DLP_helical PF18709.1 GAN07482.1 - 1.2 8.3 5.2 0.53 9.4 2.2 1.7 2 0 0 2 2 2 0 Dynamin-like helical domain F-box-like PF12937.7 GAN07483.1 - 1.2e-05 25.1 3.6 3.8e-05 23.5 1.5 2.4 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 GAN07483.1 - 0.0033 17.3 1.1 0.0078 16.1 0.3 2.0 2 0 0 2 2 2 1 F-box F-box PF00646.33 GAN07483.1 - 3.9 7.5 5.4 1.4 8.9 1.0 2.6 3 1 0 3 3 3 0 F-box domain Cyclin_C_2 PF16899.5 GAN07484.1 - 3.9e-18 65.7 1.1 2.2e-15 56.9 0.0 2.4 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 GAN07484.1 - 3.8e-09 36.3 2.0 7.4e-09 35.4 2.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAN07484.1 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat ING PF12998.7 GAN07485.1 - 5.5e-19 68.6 5.0 5.5e-19 68.6 5.0 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAN07485.1 - 5.5e-06 26.2 8.1 1e-05 25.3 8.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAN07485.1 - 0.00026 20.5 1.8 0.0005 19.6 1.8 1.5 1 0 0 1 1 1 1 PHD-finger TAN PF11640.8 GAN07485.1 - 0.014 15.6 0.6 0.014 15.6 0.6 1.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair MAS20 PF02064.15 GAN07485.1 - 0.014 15.5 1.6 0.077 13.1 0.1 2.1 2 0 0 2 2 2 0 MAS20 protein import receptor zf-HC5HC2H PF13771.6 GAN07485.1 - 0.056 13.7 1.7 0.12 12.7 1.4 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain CCDC53 PF10152.9 GAN07485.1 - 0.11 12.9 5.5 0.074 13.5 4.2 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1351 PF07083.11 GAN07485.1 - 0.97 9.2 9.7 6.4 6.5 9.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) LCD1 PF09798.9 GAN07485.1 - 1.2 7.5 5.9 1.4 7.3 5.9 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Suc_Fer-like PF06999.12 GAN07486.1 - 7.5e-58 195.6 0.0 9.7e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like TauD PF02668.16 GAN07487.1 - 3e-29 102.6 0.1 4.6e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAN07487.1 - 0.0016 17.6 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 CsiD adh_short PF00106.25 GAN07489.1 - 9.9e-41 139.3 1.5 1.5e-40 138.8 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN07489.1 - 2.4e-30 105.8 3.2 3.2e-30 105.4 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN07489.1 - 3.7e-05 23.7 0.6 0.00087 19.3 0.2 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAN07489.1 - 0.00098 18.6 0.2 0.0022 17.5 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAN07489.1 - 0.023 14.6 0.3 0.035 14.0 0.3 1.3 1 0 0 1 1 1 0 NAD(P)H-binding LuxE PF04443.12 GAN07489.1 - 0.052 12.6 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE DUF1776 PF08643.10 GAN07489.1 - 0.084 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DIOX_N PF14226.6 GAN07490.1 - 1.5e-20 74.1 0.0 2.5e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAN07490.1 - 2.4e-16 60.1 0.0 4.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SRPRB PF09439.10 GAN07490.1 - 0.2 11.1 1.3 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit dCMP_cyt_deam_1 PF00383.23 GAN07491.1 - 2e-12 46.8 0.0 3.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAN07491.1 - 1.1e-05 25.2 0.0 5.9e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAN07491.1 - 0.00017 21.7 0.5 0.0014 18.7 0.5 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase Inv-AAD PF18785.1 GAN07491.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase RHS PF03527.14 GAN07492.1 - 0.065 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 RHS protein UPF0147 PF03685.13 GAN07492.1 - 0.15 12.2 0.0 0.97 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) Zn_clus PF00172.18 GAN07493.1 - 1.5e-07 31.4 14.5 4e-07 30.1 14.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Evr1_Alr PF04777.13 GAN07494.1 - 2.9e-30 104.7 6.3 6.2e-30 103.6 6.3 1.6 1 0 0 1 1 1 1 Erv1 / Alr family F-box-like PF12937.7 GAN07495.1 - 0.0019 18.0 0.0 0.0056 16.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN07495.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 GAN07496.1 - 5.6e-67 220.0 31.0 9e-12 45.3 0.2 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07496.1 - 1.5e-24 86.1 3.8 2.2e-05 24.7 0.1 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN07496.1 - 1.1e-11 44.3 0.2 0.0021 17.1 0.0 4.6 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 GAN07496.1 - 1.2e-11 45.0 0.0 2.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 GAN07496.1 - 1.2e-08 35.0 0.0 0.01 15.7 0.0 3.6 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAN07496.1 - 9.8e-07 28.4 1.8 0.23 10.8 0.0 4.3 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 GAN07496.1 - 6.1e-06 25.2 3.9 2.4 6.7 0.0 5.8 5 1 1 6 6 6 1 Nucleoporin Nup120/160 Frtz PF11768.8 GAN07496.1 - 0.00017 20.1 0.0 0.17 10.2 0.0 2.4 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 GAN07496.1 - 0.00045 20.1 7.0 6.2 6.9 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 GAN07496.1 - 0.0062 16.2 0.2 2.3 8.0 0.0 3.7 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature IKI3 PF04762.12 GAN07496.1 - 0.0093 14.0 0.7 1.6 6.6 0.0 2.6 2 1 0 2 2 2 2 IKI3 family Nucleoporin_N PF08801.11 GAN07496.1 - 0.01 14.6 3.0 2.1 7.0 0.0 3.5 2 1 1 3 3 3 0 Nup133 N terminal like FAD_binding_9 PF08021.11 GAN07496.1 - 0.038 14.2 0.0 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 GAN07496.1 - 0.075 12.3 0.0 18 4.6 0.0 3.8 4 1 1 5 5 5 0 WD40-like domain Dus PF01207.17 GAN07497.1 - 2.2e-78 263.5 0.0 2.2e-78 263.5 0.0 1.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 GAN07497.1 - 0.00042 20.2 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 SOR/SNZ family NMO PF03060.15 GAN07497.1 - 0.0008 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 GAN07497.1 - 0.046 12.9 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 GAN07497.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 GAN07497.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 GAN07497.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG AadA_C PF18280.1 GAN07497.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain SBF_like PF13593.6 GAN07498.1 - 1.4e-87 294.0 21.0 1.7e-87 293.7 21.0 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 GAN07498.1 - 4.3e-10 39.6 11.6 4.3e-10 39.6 11.6 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family COX6B PF02297.17 GAN07499.1 - 7.9e-24 83.7 1.4 9.1e-24 83.5 1.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 GAN07499.1 - 0.0051 17.1 1.3 0.084 13.2 0.1 2.0 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 OTU PF02338.19 GAN07500.1 - 6.3e-23 81.6 0.2 1.5e-22 80.5 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAN07500.1 - 0.00063 19.3 0.0 0.003 17.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase C65 Otubain E1_UFD PF09358.10 GAN07500.1 - 0.57 10.9 2.7 6.2 7.6 0.0 2.9 2 1 1 3 3 3 0 Ubiquitin fold domain PMSR PF01625.21 GAN07501.1 - 1.5e-61 207.1 0.9 1.7e-61 206.9 0.9 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CdvA PF18822.1 GAN07501.1 - 0.1 12.4 0.1 2.1 8.2 0.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain TFIIIC_delta PF12657.7 GAN07502.1 - 2.4e-16 60.2 0.5 1.1e-14 54.8 0.4 3.1 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 GAN07502.1 - 1e-09 38.3 6.6 2.7e-09 36.9 6.6 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Dec-1 PF04624.14 GAN07502.1 - 0.0068 16.2 1.3 0.019 14.8 1.3 1.7 1 0 0 1 1 1 1 Dec-1 repeat DUF1479 PF07350.12 GAN07504.1 - 2.8e-116 388.7 0.0 2.2e-57 194.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 GAN07504.1 - 0.0003 21.1 0.0 0.0011 19.3 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PCI PF01399.27 GAN07505.1 - 7.7e-15 55.3 0.9 1.9e-14 54.1 0.0 2.1 3 0 0 3 3 3 1 PCI domain Rpn9_C PF18261.1 GAN07505.1 - 1.8e-05 24.2 1.6 3.1e-05 23.5 0.4 1.9 2 0 0 2 2 2 1 Rpn9 C-terminal helix COX5A PF02284.16 GAN07505.1 - 0.015 15.3 0.1 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va NPV_P10 PF05531.12 GAN07505.1 - 1.3 9.6 3.7 15 6.1 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AIP3 PF03915.13 GAN07506.1 - 1.6e-85 287.7 39.0 1.6e-85 287.7 39.0 2.0 2 1 0 2 2 2 1 Actin interacting protein 3 RPW8 PF05659.11 GAN07506.1 - 0.0072 16.0 4.0 0.0072 16.0 4.0 2.9 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cytochrome_C7 PF14522.6 GAN07506.1 - 0.055 13.5 0.8 0.19 11.8 0.8 1.9 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Scaffolding_pro PF11418.8 GAN07506.1 - 0.62 10.7 15.1 5.8 7.5 0.4 5.2 4 2 1 5 5 5 0 Phi29 scaffolding protein DUF4051 PF13260.6 GAN07507.1 - 0.55 10.0 6.1 1.3 8.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Proteasom_Rpn13 PF04683.13 GAN07509.1 - 4.9e-24 84.7 0.4 1.1e-23 83.5 0.4 1.6 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 GAN07509.1 - 2.5e-15 56.6 4.1 1.9e-14 53.8 4.2 2.1 1 1 1 2 2 2 1 UCH-binding domain Cas_Csa5 PF09702.10 GAN07509.1 - 0.089 13.0 0.2 0.25 11.6 0.2 1.7 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) RINGv PF12906.7 GAN07510.1 - 2.8e-07 30.6 10.2 5e-07 29.7 10.2 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 GAN07510.1 - 0.00061 19.9 6.1 0.0011 19.0 6.1 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.6 GAN07510.1 - 0.00075 19.2 6.6 0.0013 18.5 6.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GAN07510.1 - 0.0029 17.9 7.0 0.005 17.2 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain AAA_assoc PF14363.6 GAN07510.1 - 0.038 14.3 1.8 0.069 13.5 0.0 2.2 3 0 0 3 3 3 0 Domain associated at C-terminal with AAA SpoIISA_toxin PF14171.6 GAN07510.1 - 0.24 11.1 0.1 0.36 10.5 0.1 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system zinc_ribbon_5 PF13719.6 GAN07510.1 - 0.26 11.1 1.3 13 5.6 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 GAN07510.1 - 0.27 11.4 1.9 0.4 10.8 0.3 2.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C3HC4 PF00097.25 GAN07510.1 - 1.3 9.0 6.4 2.4 8.1 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 GAN07510.1 - 2.1 8.3 8.3 3.4 7.6 8.3 1.3 1 0 0 1 1 1 0 PHD-finger S1 PF00575.23 GAN07511.1 - 2.2e-14 53.6 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 GAN07511.1 - 1.4e-10 41.4 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S-AdoMet_synt_C PF02773.16 GAN07512.1 - 3.6e-68 227.8 0.3 7.1e-68 226.9 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GAN07512.1 - 8.6e-47 158.3 0.0 1.6e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GAN07512.1 - 7.1e-46 155.0 0.5 1.6e-45 153.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 GAN07512.1 - 0.034 12.9 0.6 0.13 11.0 0.2 1.9 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) SNF2_N PF00176.23 GAN07513.1 - 9e-65 218.7 0.4 2.1e-64 217.4 0.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 GAN07513.1 - 8.9e-51 171.8 18.8 8.9e-51 171.8 18.8 3.4 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 GAN07513.1 - 4.9e-17 62.3 0.3 1.5e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN07513.1 - 4.4e-06 26.8 0.0 4.4e-06 26.8 0.0 3.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAN07513.1 - 0.0041 16.3 0.0 0.0041 16.3 0.0 3.5 4 1 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 MyTH4 PF00784.17 GAN07513.1 - 4.8 7.7 10.1 5.3 7.6 0.3 3.8 3 1 1 4 4 4 0 MyTH4 domain Ras PF00071.22 GAN07514.1 - 3.9e-35 120.9 0.0 1.5e-26 93.0 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 GAN07514.1 - 4.4e-13 49.5 0.0 5.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN07514.1 - 5.2e-06 26.0 0.0 0.00044 19.8 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family AAA_7 PF12775.7 GAN07514.1 - 0.081 12.4 0.1 2.4 7.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ICL PF00463.21 GAN07515.1 - 1.5e-258 858.6 0.6 1.7e-258 858.4 0.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAN07515.1 - 5.8e-10 39.0 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Metallophos PF00149.28 GAN07516.1 - 8.3e-15 55.8 0.5 1.4e-14 55.1 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAN07516.1 - 3.9e-06 27.2 1.3 1.5e-05 25.3 0.6 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF2269 PF10027.9 GAN07516.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF1980 PF09323.10 GAN07516.1 - 0.027 14.4 0.6 0.22 11.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2561 PF10812.8 GAN07516.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Shisa PF13908.6 GAN07516.1 - 0.096 12.9 0.8 0.15 12.2 0.8 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Adap_comp_sub PF00928.21 GAN07517.1 - 3.9e-94 314.9 0.2 5.9e-94 314.3 0.2 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAN07517.1 - 1.4e-10 41.3 0.4 2.4e-10 40.5 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 GAN07517.1 - 0.034 13.2 0.1 0.048 12.7 0.1 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 F-box-like PF12937.7 GAN07518.1 - 5.9e-06 26.1 0.2 2.2e-05 24.3 0.2 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN07518.1 - 2.3e-05 24.6 5.2 11 6.6 0.0 5.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN07518.1 - 0.0019 18.1 0.0 0.0067 16.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 GAN07518.1 - 0.0098 15.6 0.9 2.7 7.8 0.0 3.7 4 0 0 4 4 4 1 Leucine rich repeat SF3b10 PF07189.11 GAN07518.1 - 0.026 14.7 0.2 0.085 13.0 0.0 1.9 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) F-box_4 PF15966.5 GAN07518.1 - 0.055 13.3 0.0 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 F-box LRR_1 PF00560.33 GAN07518.1 - 0.2 12.4 8.2 32 5.6 0.0 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GAN07518.1 - 0.28 11.4 12.7 1.4 9.2 0.1 5.6 7 0 0 7 7 7 0 Leucine Rich repeat DUF1741 PF08427.10 GAN07519.1 - 3.8e-35 121.6 6.6 8.9e-35 120.4 3.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) Dis3l2_C_term PF17877.1 GAN07520.1 - 6.7e-16 58.4 0.1 1.8e-15 57.0 0.1 1.8 1 1 0 1 1 1 1 DIS3-like exonuclease 2 C terminal p450 PF00067.22 GAN07522.1 - 2.7e-73 247.3 0.1 3.2e-73 247.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 GP38 PF05268.11 GAN07522.1 - 0.2 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Porin_3 PF01459.22 GAN07523.1 - 3.3e-69 233.4 8.1 3.7e-69 233.2 8.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin SDA1 PF05285.12 GAN07524.1 - 1.6e-87 294.2 30.7 1.6e-87 294.2 30.7 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GAN07524.1 - 1.9e-24 85.7 0.3 1.9e-24 85.7 0.3 2.1 2 0 0 2 2 2 1 NUC130/3NT domain Mating_N PF12731.7 GAN07524.1 - 0.013 15.6 0.2 0.041 14.0 0.2 1.8 1 0 0 1 1 1 0 Mating-type protein beta 1 Imm74 PF15603.6 GAN07524.1 - 0.032 14.4 0.2 0.14 12.3 0.2 2.1 1 0 0 1 1 1 0 Immunity protein 74 PSD5 PF07637.11 GAN07524.1 - 0.1 13.0 0.2 0.32 11.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) Tetraspanin PF00335.20 GAN07526.1 - 9.5e-10 38.6 12.3 1.4e-09 38.0 12.3 1.1 1 0 0 1 1 1 1 Tetraspanin family LSM PF01423.22 GAN07527.1 - 2.9e-18 65.3 0.1 3.8e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Cytochrom_C1 PF02167.15 GAN07528.1 - 3.1e-98 327.9 0.0 4.2e-98 327.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAN07528.1 - 0.0021 18.3 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 GAN07528.1 - 0.047 14.8 0.2 0.15 13.3 0.2 2.0 1 1 0 1 1 1 0 Cytochrome c ANAPC1 PF12859.7 GAN07529.1 - 1.9e-12 47.9 0.2 1.9e-12 47.9 0.2 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 GAN07529.1 - 6.7e-05 23.1 1.0 3 8.4 0.0 4.6 4 0 0 4 4 4 2 Proteasome/cyclosome repeat ATP-grasp_4 PF13535.6 GAN07529.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RNA_pol_N PF01194.17 GAN07530.1 - 2.9e-33 114.0 0.3 3.3e-33 113.8 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 GAN07531.1 - 7.3e-21 74.1 0.7 1.3e-05 25.8 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07531.1 - 9.9e-10 38.6 0.6 0.0017 18.6 0.2 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN07531.1 - 0.038 13.3 0.9 0.11 11.8 0.8 1.8 2 1 0 2 2 2 0 WD40-like domain DUF3864 PF12980.7 GAN07531.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) Hira PF07569.11 GAN07531.1 - 0.11 12.2 0.0 12 5.5 0.0 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split RIBIOP_C PF04950.12 GAN07532.1 - 8.5e-115 383.2 0.6 8.5e-115 383.2 0.6 2.0 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAN07532.1 - 1.8e-24 85.6 0.0 4.5e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Tudor_1_RapA PF18339.1 GAN07533.1 - 0.076 13.0 0.3 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain 1 5-FTHF_cyc-lig PF01812.20 GAN07534.1 - 4.1e-46 157.2 0.0 4.6e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Anp1 PF03452.14 GAN07534.1 - 0.02 14.3 0.1 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 Anp1 Sec23_trunk PF04811.15 GAN07535.1 - 5e-75 252.2 0.0 8.1e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAN07535.1 - 3.1e-25 88.0 0.1 6.7e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAN07535.1 - 1.7e-16 60.7 0.0 4.5e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAN07535.1 - 3.4e-16 59.0 2.4 6.9e-16 58.0 2.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAN07535.1 - 2.7e-08 33.6 0.0 6.9e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 GAN07535.1 - 0.00083 20.0 0.2 0.14 12.9 0.1 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Vps36-NZF-N PF16988.5 GAN07535.1 - 0.0068 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA PF00092.28 GAN07535.1 - 0.027 14.7 0.3 0.11 12.7 0.3 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Alpha_GJ PF03229.13 GAN07536.1 - 2.7 8.6 23.5 4.9 7.7 18.8 3.2 3 0 0 3 3 3 0 Alphavirus glycoprotein J THF_DHG_CYH PF00763.23 GAN07537.1 - 2.1e-25 89.3 0.2 4.8e-25 88.1 0.1 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAN07537.1 - 6.3e-15 54.8 0.1 2.5e-12 46.4 0.1 3.0 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KH_8 PF17903.1 GAN07538.1 - 5.1e-06 26.5 0.0 1.5e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 GAN07538.1 - 0.0028 17.4 0.3 0.0061 16.4 0.3 1.5 1 0 0 1 1 1 1 KH domain PHO4 PF01384.20 GAN07539.1 - 6.6e-118 393.6 20.2 7.7e-118 393.4 20.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family nos_propeller PF18764.1 GAN07539.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat Ribosomal_S27e PF01667.17 GAN07540.1 - 2.1e-30 104.2 3.6 2.5e-30 103.9 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 GAN07540.1 - 0.00055 19.4 3.1 0.00083 18.8 3.1 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.21 GAN07540.1 - 0.02 15.1 0.7 0.029 14.6 0.7 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 GAN07540.1 - 0.022 14.7 2.1 0.035 14.0 2.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2HC5 PF06221.13 GAN07540.1 - 0.031 14.3 2.5 0.031 14.3 2.5 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_4 PF13717.6 GAN07540.1 - 0.06 13.3 1.9 2 8.4 1.9 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Chitin_synth_1 PF01644.17 GAN07541.1 - 6.2e-72 240.9 0.0 1e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase DUF21 PF01595.20 GAN07541.1 - 2.4e-33 115.3 0.7 2.4e-33 115.3 0.7 2.1 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Chitin_synth_1N PF08407.11 GAN07541.1 - 1.6e-25 88.8 0.4 5.2e-25 87.2 0.4 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAN07541.1 - 2e-20 72.9 6.0 5.4e-18 64.9 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN07541.1 - 6.8e-09 35.9 0.4 6.8e-09 35.9 0.4 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 CBS PF00571.28 GAN07541.1 - 3.2e-07 30.7 0.1 0.036 14.5 0.1 2.8 2 0 0 2 2 2 2 CBS domain Glyco_tranf_2_3 PF13641.6 GAN07541.1 - 0.00013 22.0 0.0 0.00033 20.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GYR PF02756.14 GAN07541.1 - 1.3 8.8 4.1 3.1 7.6 4.1 1.6 1 0 0 1 1 1 0 GYR motif CBS PF00571.28 GAN07542.1 - 1.3e-19 70.3 0.6 0.00055 20.3 0.0 4.5 4 1 0 4 4 4 4 CBS domain HSM3_N PF18795.1 GAN07542.1 - 0.0062 16.0 1.5 0.012 15.1 1.5 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain Chitin_synth_2 PF03142.15 GAN07544.1 - 3.2e-232 771.8 4.7 5.2e-232 771.1 4.7 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAN07544.1 - 3.5e-13 50.0 0.1 7.1e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN07544.1 - 2.9e-10 40.4 7.4 1e-09 38.6 7.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GAN07544.1 - 0.00033 20.2 0.1 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAN07544.1 - 0.018 14.8 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Orthoreo_P10 PF07204.11 GAN07544.1 - 0.1 12.5 0.6 0.4 10.7 0.6 2.0 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 HMG_box PF00505.19 GAN07545.1 - 3.4e-25 88.2 1.9 4.9e-25 87.7 1.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN07545.1 - 6e-19 68.4 2.3 6e-19 68.4 2.3 1.4 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 GAN07545.1 - 0.00035 20.5 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.6 GAN07545.1 - 0.02 14.8 3.8 0.022 14.7 3.5 1.5 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Fungal_trans PF04082.18 GAN07546.1 - 2.9e-44 151.1 0.4 2.9e-44 151.1 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN07546.1 - 9.8e-10 38.4 13.6 1.9e-09 37.5 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 GAN07546.1 - 0.39 10.8 28.3 0.15 12.1 7.5 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4820 PF16091.5 GAN07546.1 - 3.3 7.0 7.8 4.2 6.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) D123 PF07065.14 GAN07547.1 - 2.2e-105 352.2 6.2 3.1e-105 351.7 6.2 1.2 1 0 0 1 1 1 1 D123 adh_short_C2 PF13561.6 GAN07548.1 - 1.5e-69 234.1 0.3 1.7e-69 234.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN07548.1 - 4.1e-53 179.8 1.1 5e-53 179.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN07548.1 - 1.2e-10 41.6 0.7 1.8e-10 41.0 0.7 1.2 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.14 GAN07548.1 - 0.00012 21.7 0.4 0.00019 21.1 0.4 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAN07548.1 - 0.0021 18.0 0.5 0.0035 17.2 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAN07548.1 - 0.0024 17.4 0.2 0.0033 16.9 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family IL8 PF00048.20 GAN07548.1 - 0.17 12.1 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like RAI16-like PF10257.9 GAN07549.1 - 7.4e-77 258.6 0.8 1.2e-76 258.0 0.8 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF3772 PF12607.8 GAN07549.1 - 0.09 12.6 0.9 0.21 11.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Carboxyl_trans PF01039.22 GAN07550.1 - 8.2e-76 255.6 0.0 9.9e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain RRM_1 PF00076.22 GAN07551.1 - 1.1e-25 89.3 0.0 4.5e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CNOT1_TTP_bind PF16417.5 GAN07551.1 - 0.21 10.7 9.4 0.85 8.8 6.6 2.4 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain FAM76 PF16046.5 GAN07551.1 - 0.83 9.0 14.4 0.21 10.9 8.9 2.1 2 0 0 2 2 2 0 FAM76 protein PseudoU_synth_2 PF00849.22 GAN07552.1 - 7.7e-29 100.8 0.0 1.5e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase Spc110_C PF18520.1 GAN07552.1 - 0.14 11.8 0.2 0.55 9.9 0.1 2.0 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain HLH PF00010.26 GAN07553.1 - 8.6e-12 44.8 0.3 1.9e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIF_alpha PF05793.12 GAN07553.1 - 1.8 7.1 15.0 2.6 6.5 15.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4472 PF14739.6 GAN07553.1 - 2.2 9.1 10.9 0.4 11.4 5.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) SNF2_N PF00176.23 GAN07554.1 - 1e-63 215.2 0.4 2.4e-63 214.0 0.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN07554.1 - 1.6e-19 70.3 0.0 1.1e-18 67.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN07554.1 - 1.8e-11 44.3 0.0 1.8e-11 44.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 GAN07554.1 - 1e-10 41.8 6.5 1e-10 41.8 6.5 4.6 3 1 1 4 4 4 1 HSA Cation_ATPase PF13246.6 GAN07554.1 - 2.9 8.0 4.4 1e+02 3.1 0.2 4.1 4 0 0 4 4 4 0 Cation transport ATPase (P-type) PHD PF00628.29 GAN07555.1 - 6.8e-06 25.9 17.4 8.9e-06 25.5 12.1 2.6 2 0 0 2 2 2 1 PHD-finger BSP_II PF05432.11 GAN07555.1 - 0.016 15.0 7.6 0.028 14.1 7.6 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 GAN07555.1 - 0.021 15.2 1.8 0.021 15.2 1.8 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 GAN07555.1 - 0.31 10.9 8.1 0.54 10.1 8.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PGA2 PF07543.12 GAN07555.1 - 0.45 10.5 8.2 1 9.3 8.2 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 PHD_2 PF13831.6 GAN07555.1 - 2.6 7.7 10.4 0.7 9.5 6.1 2.2 2 0 0 2 2 2 0 PHD-finger LAG1-DNAbind PF09271.11 GAN07556.1 - 3.7e-46 157.5 0.2 3.7e-46 157.5 0.2 2.5 3 0 0 3 3 3 1 LAG1, DNA binding BTD PF09270.10 GAN07556.1 - 6.4e-23 81.7 0.3 6.6e-21 75.1 0.3 3.2 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain C12orf66_like PF09404.10 GAN07557.1 - 8.7e-49 166.5 0.1 1.2e-48 166.1 0.1 1.1 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like Exo70 PF03081.15 GAN07557.1 - 0.039 13.0 0.6 0.061 12.4 0.6 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit AhpC-TSA PF00578.21 GAN07559.1 - 2.1e-17 63.2 0.0 2.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAN07559.1 - 2.3e-07 30.6 0.0 3.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Surfac_D-trimer PF09006.11 GAN07559.1 - 0.19 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation NUC153 PF08159.12 GAN07560.1 - 1.5e-11 43.9 1.8 2.7e-11 43.1 1.8 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 GAN07560.1 - 0.00017 21.9 0.0 0.14 12.4 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN07560.1 - 0.096 13.6 0.0 11 7.1 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Phosphoprotein PF00922.17 GAN07560.1 - 0.28 10.7 5.2 0.55 9.8 5.2 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein CDC45 PF02724.14 GAN07560.1 - 9.5 4.4 14.7 14 3.9 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_jaz PF12171.8 GAN07561.1 - 0.008 16.5 0.8 0.026 14.8 0.1 2.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 GAN07561.1 - 0.0083 16.2 1.0 0.025 14.6 1.0 1.8 1 0 0 1 1 1 1 CpXC protein zf-C2H2_4 PF13894.6 GAN07561.1 - 0.047 14.5 10.1 0.2 12.6 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 GAN07561.1 - 0.077 13.4 0.1 0.27 11.7 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAN07561.1 - 9.2 7.0 14.2 1.1 9.8 0.2 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Tubulin PF00091.25 GAN07563.1 - 2.6e-46 158.3 0.0 4.7e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAN07563.1 - 3.5e-41 140.3 0.0 5.4e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAN07563.1 - 0.024 14.3 0.8 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 Tubulin domain Tubulin_2 PF13809.6 GAN07563.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Hydrolase_4 PF12146.8 GAN07563.1 - 0.13 11.6 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Adaptin_N PF01602.20 GAN07566.1 - 3.4e-100 336.1 5.4 4.5e-100 335.7 5.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAN07566.1 - 4.3e-54 182.8 3.8 9.4e-54 181.7 3.8 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 GAN07566.1 - 8.7e-20 70.9 0.2 2.1e-10 40.9 0.0 4.9 3 1 1 4 4 4 4 HEAT repeats Cnd1 PF12717.7 GAN07566.1 - 1.1e-14 54.9 2.9 2.3e-06 27.7 0.0 4.0 3 2 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAN07566.1 - 2.5e-05 24.1 9.4 4 8.0 0.1 7.3 8 0 0 8 8 8 1 HEAT repeat Arm PF00514.23 GAN07566.1 - 0.024 14.7 0.0 3.2 7.9 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 GAN07566.1 - 0.088 13.0 0.6 1.1e+02 3.1 0.0 4.9 4 2 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Rrf2 PF02082.20 GAN07566.1 - 0.11 12.9 0.0 19 5.7 0.0 3.1 2 0 0 2 2 2 0 Transcriptional regulator HEAT_PBS PF03130.16 GAN07566.1 - 0.45 11.3 7.5 7.3 7.6 0.0 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 GAN07566.1 - 0.96 10.0 3.7 16 6.1 0.2 3.9 4 0 0 4 4 4 0 HEAT-like repeat Pkinase PF00069.25 GAN07567.1 - 3.3e-47 161.1 0.1 5.7e-47 160.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07567.1 - 3.2e-23 82.3 0.0 1.6e-22 80.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN07567.1 - 0.0011 18.4 0.0 0.0028 17.0 0.0 1.7 1 0 0 1 1 1 1 Kinase-like RabGAP-TBC PF00566.18 GAN07568.1 - 3.1e-54 183.9 0.2 3.1e-54 183.9 0.2 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Shugoshin_N PF07558.11 GAN07568.1 - 0.37 10.7 5.3 0.38 10.7 0.9 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF2381 PF09544.10 GAN07568.1 - 0.57 9.7 4.2 0.67 9.4 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2381) V-SNARE_C PF12352.8 GAN07569.1 - 3.4e-13 49.7 0.9 3.4e-13 49.7 0.9 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus APG17 PF04108.12 GAN07569.1 - 0.00056 19.1 2.6 0.00071 18.8 2.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 T4SS PF07996.11 GAN07569.1 - 0.076 13.4 2.3 1 9.8 2.3 2.4 1 1 0 1 1 1 0 Type IV secretion system proteins Rx_N PF18052.1 GAN07569.1 - 0.1 12.9 0.4 2.2 8.6 0.0 2.5 2 1 0 2 2 2 0 Rx N-terminal domain DUF848 PF05852.11 GAN07569.1 - 0.4 10.8 5.0 1.2 9.3 0.4 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF966 PF06136.13 GAN07570.1 - 1.4 8.5 25.7 3 7.5 25.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LAP1C PF05609.12 GAN07570.1 - 3.4 6.6 34.5 4.5 6.3 34.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MMR1 PF08505.10 GAN07570.1 - 6.2 7.0 45.1 11 6.2 45.1 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF572 PF04502.13 GAN07570.1 - 6.8 6.2 38.8 11 5.5 38.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) His_biosynth PF00977.21 GAN07571.1 - 3.1e-50 170.8 0.1 1.8e-49 168.3 0.1 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 GAN07571.1 - 8.6e-21 74.6 0.0 1.4e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 GAN07571.1 - 2.6e-09 37.2 0.0 1.4e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAN07571.1 - 1.2e-08 34.8 0.0 2.6e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain NMO PF03060.15 GAN07571.1 - 0.01 15.3 0.2 0.041 13.3 0.0 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase Peptidase_C26 PF07722.13 GAN07571.1 - 0.011 15.5 0.1 0.057 13.2 0.1 2.1 1 1 0 1 1 1 0 Peptidase C26 BPL_N PF09825.9 GAN07571.1 - 0.039 13.0 0.0 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal ThiG PF05690.14 GAN07571.1 - 0.088 12.1 0.2 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 GAN07571.1 - 0.23 10.5 0.0 0.45 9.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Mcp5_PH PF12814.7 GAN07572.1 - 5.3e-34 116.9 0.4 2.4e-33 114.8 0.0 2.5 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Retrotrans_gag PF03732.17 GAN07573.1 - 0.0031 17.8 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein HTH_7 PF02796.15 GAN07574.1 - 0.0015 18.5 0.2 0.056 13.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_Tc3_2 PF01498.18 GAN07574.1 - 0.0067 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 GAN07574.1 - 0.021 14.6 0.5 0.085 12.7 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 GAN07574.1 - 0.032 14.2 0.9 0.3 11.1 0.9 2.3 1 1 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 GAN07574.1 - 0.043 14.4 0.2 0.52 11.0 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Mon1 PF03164.14 GAN07575.1 - 4.8e-136 454.0 3.8 5.6e-136 453.8 3.8 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Redoxin PF08534.10 GAN07575.1 - 0.11 12.2 0.0 0.63 9.7 0.0 2.2 3 0 0 3 3 3 0 Redoxin SBDS_C PF09377.10 GAN07576.1 - 4.1e-40 136.4 1.2 4.1e-40 136.4 1.2 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 GAN07576.1 - 2.2e-34 117.4 0.7 4e-34 116.5 0.7 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Csa1 PF06023.12 GAN07576.1 - 0.055 12.8 0.2 0.074 12.4 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 2-Hacid_dh_C PF02826.19 GAN07576.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UCH PF00443.29 GAN07577.1 - 1.5e-48 165.6 0.0 2.2e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN07577.1 - 1.2e-11 44.9 1.0 6.4e-11 42.4 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ndc1_Nup PF09531.10 GAN07577.1 - 0.57 8.8 11.4 0.83 8.3 11.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FSA_C PF10479.9 GAN07577.1 - 4.5 5.3 9.4 6.9 4.7 9.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Stm1_N PF09598.10 GAN07578.1 - 0.89 10.5 6.1 1.7 9.6 6.1 1.5 1 0 0 1 1 1 0 Stm1 Methyltransf_11 PF08241.12 GAN07579.1 - 2.6e-14 53.6 0.0 4.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN07579.1 - 1.7e-12 47.8 0.0 4.7e-12 46.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN07579.1 - 8.4e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN07579.1 - 3e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN07579.1 - 7.5e-05 23.4 0.0 0.00018 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN07579.1 - 0.007 16.2 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain RrnaAD PF00398.20 GAN07579.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 GAN07579.1 - 0.033 13.3 0.0 0.099 11.7 0.0 1.6 1 1 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 GAN07579.1 - 0.055 13.0 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.15 GAN07579.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase TehB PF03848.14 GAN07579.1 - 0.081 12.3 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB MFS_1 PF07690.16 GAN07581.1 - 2.1e-27 96.0 28.1 2.9e-27 95.6 27.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NUDIX PF00293.28 GAN07583.1 - 3.4e-08 33.6 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NPR3 PF03666.13 GAN07583.1 - 0.025 13.4 4.5 0.036 12.9 4.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3464 PF11947.8 GAN07583.1 - 0.25 11.1 5.5 0.37 10.5 5.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AP3D1 PF06375.11 GAN07583.1 - 0.4 10.9 13.6 0.68 10.2 13.6 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Sec62 PF03839.16 GAN07583.1 - 1.9 7.9 9.0 3.5 7.1 9.0 1.3 1 1 0 1 1 1 0 Translocation protein Sec62 TMEM214 PF10151.9 GAN07583.1 - 2 6.8 8.8 2.7 6.3 8.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator FKBP_C PF00254.28 GAN07584.1 - 3.3e-20 72.2 0.0 4.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase OPA3 PF07047.12 GAN07585.1 - 5.7e-46 155.4 0.4 5.7e-46 155.4 0.4 1.5 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) REC1 PF18501.1 GAN07585.1 - 0.0088 16.0 1.4 0.016 15.1 1.4 1.4 1 0 0 1 1 1 1 Alpha helical recognition lobe domain DUF3450 PF11932.8 GAN07585.1 - 0.031 13.6 2.5 0.048 12.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NicO PF03824.16 GAN07585.1 - 0.054 12.8 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein MSC PF09402.10 GAN07585.1 - 0.085 12.3 0.3 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain KIAA1430 PF13879.6 GAN07585.1 - 0.092 13.5 5.5 0.17 12.6 5.1 1.7 1 1 0 1 1 1 0 KIAA1430 homologue bZIP_2 PF07716.15 GAN07585.1 - 0.36 10.9 10.0 2 8.6 0.9 2.4 1 1 1 2 2 2 0 Basic region leucine zipper NYD-SP28_assoc PF14775.6 GAN07585.1 - 2.8 8.1 10.1 13 6.0 0.8 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain GATase_6 PF13522.6 GAN07586.1 - 1.7e-16 60.7 0.0 3.5e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAN07586.1 - 2.2e-13 50.2 0.0 5.5e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GAN07586.1 - 1.5e-07 31.1 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 GAN07586.1 - 3.5e-06 26.1 0.0 1.1e-05 24.4 0.0 1.7 1 1 0 2 2 2 1 Glutamine amidotransferases class-II HEPN_AbiU2 PF18734.1 GAN07586.1 - 0.042 13.4 1.8 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 AbiU2 IlvN PF07991.12 GAN07587.1 - 5.4e-45 152.9 0.0 9.8e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 GAN07587.1 - 1.3e-41 142.3 0.0 2.1e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 GAN07587.1 - 0.0077 16.8 0.1 0.047 14.3 0.0 2.3 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAN07587.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 GAN07587.1 - 0.083 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_transf_49 PF13896.6 GAN07588.1 - 8.4e-43 147.0 0.3 2.8e-33 115.7 0.1 2.5 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan OB_RNB PF08206.11 GAN07588.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain DUF104 PF01954.16 GAN07588.1 - 0.077 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 Phosphoesterase PF04185.14 GAN07589.1 - 1.1e-31 110.3 8.2 8.4e-30 104.1 2.8 3.0 1 1 1 2 2 2 2 Phosphoesterase family Isochorismatase PF00857.20 GAN07590.1 - 1.7e-21 77.2 0.0 3.2e-21 76.3 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family DnaJ_C PF01556.18 GAN07591.1 - 1.6e-42 145.1 0.3 2e-42 144.8 0.3 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN07591.1 - 3.7e-27 94.2 1.0 6.1e-27 93.5 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAN07591.1 - 7.9e-16 58.2 19.7 1.2e-15 57.6 19.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAN07591.1 - 0.017 15.0 14.4 0.068 13.1 2.1 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAN07591.1 - 0.21 11.6 12.9 1.4 8.9 3.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4769 PF15992.5 GAN07591.1 - 0.22 11.3 0.3 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) DUF1687 PF07955.11 GAN07592.1 - 1e-06 29.2 0.0 1.5e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 GAN07592.1 - 3.2e-05 23.8 0.1 5.2e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 ArsC family SBF PF01758.16 GAN07593.1 - 7e-53 179.2 11.1 7e-53 179.2 11.1 2.2 3 0 0 3 3 3 1 Sodium Bile acid symporter family CotH PF08757.11 GAN07594.1 - 1.4e-39 136.5 0.1 2.7e-39 135.6 0.1 1.4 1 0 0 1 1 1 1 CotH kinase protein Peptidase_M13_N PF05649.13 GAN07595.1 - 1.1e-87 295.2 1.6 1.1e-87 295.2 1.6 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAN07595.1 - 9.7e-70 234.3 0.1 1.9e-69 233.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 DUF1283 PF06932.11 GAN07595.1 - 0.0065 16.7 0.2 0.019 15.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) Lipase_GDSL_2 PF13472.6 GAN07596.1 - 2.9e-05 24.6 0.0 5.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PAPS_reduct PF01507.19 GAN07597.1 - 9.3e-31 107.2 0.0 8e-22 78.1 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family HD PF01966.22 GAN07598.1 - 2e-07 31.2 0.0 3.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 GAN07598.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 HDOD domain HD_4 PF13328.6 GAN07598.1 - 0.00036 20.3 0.4 0.00065 19.5 0.4 1.4 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 GAN07598.1 - 0.0028 17.3 0.1 0.0048 16.5 0.1 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase HD_6 PF18019.1 GAN07598.1 - 0.072 13.2 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 HD domain PhyH PF05721.13 GAN07599.1 - 4.6e-31 108.7 0.0 5.7e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAN07599.1 - 0.0035 17.7 0.0 0.0069 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Integrase_H2C2 PF17921.1 GAN07600.1 - 8.5e-08 32.2 1.6 1e-07 31.9 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GAN07600.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger zf-RING_2 PF13639.6 GAN07601.1 - 4.1e-12 46.2 8.0 7.1e-12 45.5 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN07601.1 - 2.6e-09 36.8 7.5 4.6e-09 36.0 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN07601.1 - 2.1e-08 33.9 6.9 3.9e-08 33.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN07601.1 - 1.6e-06 27.9 8.3 2.5e-06 27.2 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN07601.1 - 2.5e-06 27.3 6.2 4.3e-06 26.6 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAN07601.1 - 8.7e-06 25.7 2.1 8.7e-06 25.7 2.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAN07601.1 - 4.1e-05 23.2 4.3 4.1e-05 23.2 4.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 GAN07601.1 - 0.00026 21.2 7.9 0.001 19.3 7.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAN07601.1 - 0.00049 19.9 7.8 0.0011 18.8 7.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAN07601.1 - 0.024 14.8 8.6 0.047 13.9 8.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING EarP PF10093.9 GAN07601.1 - 0.048 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP zf-UDP PF14569.6 GAN07601.1 - 0.19 11.8 3.2 0.53 10.4 3.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 GAN07601.1 - 0.22 11.6 3.9 0.49 10.5 3.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 GAN07601.1 - 0.62 9.8 7.8 1.2 8.9 7.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 GAN07601.1 - 5.1 7.0 11.2 11 5.9 11.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GAN07602.1 - 1.4e-11 44.5 7.4 2.6e-11 43.7 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN07602.1 - 1.8e-11 43.5 0.9 4.4e-11 42.3 0.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAN07602.1 - 3.5e-09 36.4 6.7 5.9e-09 35.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 GAN07602.1 - 1.2e-08 34.9 0.0 1e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 PA domain zf-C3HC4 PF00097.25 GAN07602.1 - 2.9e-06 27.1 5.7 5.6e-06 26.1 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN07602.1 - 0.00017 21.6 0.8 0.00017 21.6 0.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAN07602.1 - 0.00023 21.4 9.1 0.0013 19.0 9.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN07602.1 - 0.013 15.5 6.3 0.022 14.7 6.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN07602.1 - 0.021 14.7 5.8 0.036 13.9 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN07602.1 - 0.026 14.6 1.1 0.06 13.4 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAN07602.1 - 0.086 12.7 6.9 0.17 11.8 6.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAN07602.1 - 0.22 11.7 4.2 1.5 9.1 3.3 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 GAN07602.1 - 0.43 10.3 5.8 0.85 9.3 5.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 GAN07602.1 - 0.68 10.0 6.6 2 8.5 6.6 1.8 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 GAN07602.1 - 1.3 9.0 6.4 3.2 7.8 6.4 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 GAN07602.1 - 4.9 7.5 6.3 9.9 6.6 6.3 1.5 1 0 0 1 1 1 0 RING-like domain DUF2689 PF10894.8 GAN07604.1 - 0.0099 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2689) DEC-1_N PF04625.13 GAN07604.1 - 0.51 9.3 12.7 0.61 9.0 12.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.19 GAN07605.1 - 0.35 11.5 2.5 0.68 10.6 2.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein ADH_N PF08240.12 GAN07609.1 - 1.2e-24 86.3 3.6 1.2e-24 86.3 3.6 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN07609.1 - 3.6e-19 69.0 0.1 8.5e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN07609.1 - 0.0035 18.4 0.0 0.0061 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 GAN07609.1 - 0.062 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 GAN07609.1 - 0.072 12.4 0.2 0.14 11.4 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Met_10 PF02475.16 GAN07609.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein 2-Hacid_dh_C PF02826.19 GAN07609.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C3HC4_3 PF13920.6 GAN07610.1 - 7.8e-06 25.7 13.9 1.5e-05 24.8 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN07610.1 - 0.0002 21.3 15.1 0.00045 20.1 15.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAN07610.1 - 0.0041 16.9 10.7 0.0081 16.0 10.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAN07610.1 - 0.0049 17.1 9.8 0.014 15.7 9.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAN07610.1 - 0.0049 16.7 14.7 0.011 15.6 14.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN07610.1 - 0.0062 16.4 16.2 0.014 15.2 16.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN07610.1 - 0.0075 16.6 15.3 0.016 15.6 15.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAN07610.1 - 0.016 15.3 8.7 0.057 13.5 8.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger TRPM_tetra PF16519.5 GAN07610.1 - 0.017 15.2 5.5 0.11 12.6 4.8 3.0 2 1 0 2 2 2 0 Tetramerisation domain of TRPM zf-ANAPC11 PF12861.7 GAN07610.1 - 0.038 14.0 2.6 0.088 12.9 2.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAN07610.1 - 0.42 10.5 6.2 1.1 9.2 6.2 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein T2SSF PF00482.23 GAN07610.1 - 1 9.3 3.1 1.5 8.8 0.3 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F zf-C3HC4_4 PF15227.6 GAN07610.1 - 7.1 6.9 10.7 20 5.5 10.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Scs3p PF10261.9 GAN07613.1 - 4.5e-32 111.5 15.5 2.3e-25 89.5 0.8 2.0 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 GAN07613.1 - 0.00012 21.8 2.8 0.00015 21.6 2.8 1.1 1 0 0 1 1 1 1 PAP2 superfamily DUF5445 PF17520.2 GAN07613.1 - 0.61 10.0 0.1 0.61 10.0 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5445) UCH PF00443.29 GAN07614.1 - 8.2e-42 143.5 0.4 1.5e-41 142.6 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 GAN07614.1 - 1e-25 89.2 2.7 1.9e-23 82.0 0.4 2.8 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 GAN07614.1 - 4.4e-24 84.6 11.7 3.3e-19 68.9 2.4 3.8 5 0 0 5 5 5 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAN07614.1 - 7.1e-16 58.7 25.5 1.5e-15 57.6 16.6 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 GAN07614.1 - 4.3e-15 55.2 0.0 7.5e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zinc_ribbon_12 PF11331.8 GAN07614.1 - 0.21 11.4 5.7 0.33 10.8 0.2 3.8 4 0 0 4 4 4 0 Probable zinc-ribbon domain 4HBT_3 PF13622.6 GAN07615.1 - 9.3e-61 206.2 0.1 1.1e-60 206.0 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 GAN07615.1 - 1.2e-33 115.8 0.0 2.3e-28 98.7 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase cwf18 PF08315.12 GAN07616.1 - 3.8e-36 124.7 16.6 3.8e-36 124.7 16.6 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Microtub_bind PF13931.6 GAN07617.1 - 0.032 14.6 1.5 0.046 14.1 1.5 1.1 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Pkinase_C PF00433.24 GAN07617.1 - 0.089 13.5 0.4 0.25 12.1 0.4 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain CPSase_L_D2 PF02786.17 GAN07618.1 - 1.3e-79 266.6 0.4 2.3e-79 265.8 0.4 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAN07618.1 - 1.7e-72 243.3 0.0 2.8e-72 242.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAN07618.1 - 8e-40 135.8 0.1 1.8e-39 134.7 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN07618.1 - 1.7e-31 108.5 0.0 1e-30 106.0 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAN07618.1 - 3.1e-29 102.3 0.0 6.4e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAN07618.1 - 1.5e-18 66.4 3.7 8.4e-18 64.0 1.5 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAN07618.1 - 5.7e-14 51.7 0.7 2.8e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAN07618.1 - 8.9e-10 38.4 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 GAN07618.1 - 2.4e-08 34.6 2.6 0.0062 17.2 0.3 3.4 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.22 GAN07618.1 - 3.1e-07 30.1 0.1 7e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAN07618.1 - 5.8e-05 23.2 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 GAN07618.1 - 0.00011 21.4 0.3 0.028 13.6 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 GAN07618.1 - 0.0011 18.6 0.1 0.016 14.8 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 GAN07618.1 - 0.0031 17.3 0.0 0.018 14.8 0.0 2.2 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 GAN07618.1 - 0.004 17.1 0.2 0.018 15.0 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 GAN07618.1 - 0.0061 16.4 0.1 0.044 13.7 0.3 2.3 2 0 0 2 2 2 1 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 GAN07618.1 - 0.011 15.0 0.0 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp NQRA PF05896.11 GAN07618.1 - 0.014 14.9 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF3182 PF11379.8 GAN07618.1 - 0.068 12.1 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) PNPase PF03726.14 GAN07618.1 - 0.11 13.0 0.1 0.39 11.2 0.1 2.0 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain KAR9 PF08580.10 GAN07619.1 - 7.9e-11 41.2 46.3 1.8e-06 26.9 36.2 4.4 1 1 1 2 2 2 2 Yeast cortical protein KAR9 DUF1285 PF06938.11 GAN07619.1 - 0.0013 18.7 0.1 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1285) Syntaxin-6_N PF09177.11 GAN07619.1 - 0.62 10.6 3.8 11 6.7 0.1 3.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal HEAT PF02985.22 GAN07620.1 - 5.5e-18 63.5 11.0 0.00027 20.9 0.0 9.9 10 0 0 10 10 9 3 HEAT repeat HEAT_EZ PF13513.6 GAN07620.1 - 3.7e-16 59.2 7.3 2.1e-11 44.1 0.0 7.1 7 1 0 7 7 7 1 HEAT-like repeat IBN_N PF03810.19 GAN07620.1 - 3.8e-11 42.7 1.9 1.1e-09 38.0 0.5 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 GAN07620.1 - 5.3e-09 36.3 6.8 0.0041 17.5 0.0 6.8 5 3 3 8 8 8 3 HEAT repeats Arm PF00514.23 GAN07620.1 - 7.5e-05 22.6 4.4 0.021 14.9 0.0 5.4 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 GAN07620.1 - 0.00048 19.9 1.5 5.1 6.8 0.0 4.4 3 1 0 4 4 4 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 GAN07620.1 - 0.0007 19.5 5.4 6.1 6.7 0.1 5.4 4 2 1 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 GAN07620.1 - 0.0014 18.3 3.5 0.93 9.0 0.2 4.4 4 1 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.8 GAN07620.1 - 0.0037 16.4 7.6 0.95 8.5 0.0 4.1 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 GAN07620.1 - 0.014 15.2 4.7 1.4 8.6 0.0 4.4 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 GAN07620.1 - 0.073 12.6 0.7 19 4.7 0.2 4.0 2 2 0 3 3 3 0 Tti2 family Proteasom_PSMB PF10508.9 GAN07620.1 - 0.082 11.4 4.1 0.62 8.5 0.0 3.0 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit Pkinase PF00069.25 GAN07621.1 - 9.5e-46 156.3 0.1 3.8e-27 95.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07621.1 - 4.8e-24 85.0 0.0 4.1e-13 49.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAN07621.1 - 1.5e-05 25.0 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN07621.1 - 0.0044 16.4 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FUSC_2 PF13515.6 GAN07622.1 - 2.4e-18 66.5 12.2 2.4e-18 66.5 12.2 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 GAN07622.1 - 2.3e-13 50.5 0.4 2.3e-13 50.5 0.4 2.2 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 FUSC PF04632.12 GAN07622.1 - 3.3e-13 49.1 12.2 6.5e-13 48.1 3.0 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.8 GAN07622.1 - 3.8e-13 49.1 17.3 2.7e-11 43.0 1.2 3.6 2 1 0 2 2 2 2 Aluminium activated malate transporter DUF4295 PF14128.6 GAN07622.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) DUF2956 PF11169.8 GAN07622.1 - 0.13 12.5 1.1 0.4 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) WD40 PF00400.32 GAN07623.1 - 2.2e-54 180.2 24.9 5.3e-08 33.4 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 GAN07623.1 - 3.5e-13 49.2 0.4 6.8e-13 48.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 GAN07623.1 - 1.3e-10 40.6 14.1 0.03 13.0 0.3 6.2 2 1 3 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN07623.1 - 1.3e-09 38.3 4.5 0.02 15.2 0.1 5.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAN07623.1 - 2.6e-09 36.7 0.2 5.8e-09 35.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 GAN07623.1 - 0.00055 19.3 0.4 0.66 9.2 0.0 3.4 3 1 1 4 4 4 1 WD40-like domain F-box_4 PF15966.5 GAN07623.1 - 0.0042 17.0 0.2 0.068 13.1 0.0 2.8 3 0 0 3 3 3 1 F-box BBS2_Mid PF14783.6 GAN07623.1 - 0.0074 16.3 0.1 2.5 8.2 0.0 4.0 3 2 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 GAN07623.1 - 0.009 15.0 10.5 1.9 7.3 0.2 4.6 2 2 3 5 5 5 3 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 GAN07623.1 - 0.074 11.8 4.3 3.8 6.1 0.1 4.0 3 2 1 4 4 4 0 Nup133 N terminal like Ge1_WD40 PF16529.5 GAN07623.1 - 0.62 9.0 4.8 7.8 5.4 0.0 3.4 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAM104 PF15434.6 GAN07623.1 - 1.3 9.6 6.7 1.3 9.6 1.4 2.2 2 0 0 2 2 2 0 Family 104 bZIP_2 PF07716.15 GAN07624.1 - 1.3e-10 41.2 10.6 2.2e-10 40.4 10.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN07624.1 - 0.00081 19.4 7.6 0.0016 18.5 7.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.9 GAN07624.1 - 0.0017 18.5 1.5 0.0039 17.4 1.5 1.6 1 0 0 1 1 1 1 Haemolysin XhlA SLAIN PF15301.6 GAN07624.1 - 0.002 17.4 7.7 0.0041 16.5 7.7 1.4 1 0 0 1 1 1 1 SLAIN motif-containing family MPS2 PF17060.5 GAN07624.1 - 0.13 11.5 2.6 0.2 10.9 2.6 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4097 PF13349.6 GAN07625.1 - 3.9e-10 39.5 4.6 4.6e-09 36.0 4.5 2.3 1 1 0 1 1 1 1 Putative adhesin DUF3971 PF13116.6 GAN07625.1 - 0.24 11.0 4.8 0.17 11.4 0.7 2.4 2 1 0 3 3 3 0 Protein of unknown function WRKY PF03106.15 GAN07627.1 - 1e-10 41.6 2.5 1e-10 41.6 2.5 2.5 3 0 0 3 3 3 1 WRKY DNA -binding domain SURF6 PF04935.12 GAN07627.1 - 3.7 7.3 17.3 0.57 10.0 8.7 2.3 2 0 0 2 2 2 0 Surfeit locus protein 6 RcpC PF16976.5 GAN07627.1 - 6.4 6.9 8.0 1.2 9.2 2.6 2.3 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB Metallophos PF00149.28 GAN07628.1 - 4.3e-12 47.0 2.5 6.9e-12 46.3 2.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S1 PF00575.23 GAN07629.1 - 1.2e-46 156.9 23.4 4.1e-07 30.2 0.1 10.5 10 0 0 10 10 10 8 S1 RNA binding domain Suf PF05843.14 GAN07629.1 - 1.3e-08 35.2 0.5 1.3e-08 35.2 0.5 5.0 3 1 3 6 6 6 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 GAN07629.1 - 7.9e-06 26.3 0.0 0.46 11.4 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN07629.1 - 3.7e-05 24.2 0.0 0.42 11.2 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN07629.1 - 0.00063 19.7 0.1 0.01 15.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAN07629.1 - 0.0011 18.3 0.6 0.007 15.6 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN07629.1 - 0.0093 16.2 0.2 0.088 13.1 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN07629.1 - 0.022 15.4 0.0 0.11 13.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 GAN07629.1 - 0.064 13.5 0.4 72 4.0 0.0 3.6 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 GAN07629.1 - 0.077 13.7 0.1 49 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN07629.1 - 0.083 12.7 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN07629.1 - 0.094 13.0 0.0 8.6 6.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat BUD22 PF09073.10 GAN07629.1 - 0.88 8.9 40.8 0.034 13.5 24.6 3.3 3 0 0 3 3 3 0 BUD22 SDA1 PF05285.12 GAN07629.1 - 9.6 5.5 41.2 0.13 11.6 27.4 3.2 3 0 0 3 3 3 0 SDA1 Polysacc_deac_1 PF01522.21 GAN07630.1 - 1e-25 90.0 0.0 2.1e-25 89.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase RE_Eco47II PF09553.10 GAN07630.1 - 0.0053 16.3 0.3 0.074 12.6 0.1 2.1 2 0 0 2 2 2 1 Eco47II restriction endonuclease DUF2334 PF10096.9 GAN07630.1 - 0.011 15.4 0.5 0.025 14.2 0.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Hexokinase_2 PF03727.16 GAN07631.1 - 1.5e-59 201.3 0.0 2e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN07631.1 - 7.3e-52 176.2 0.0 1.1e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF155 PF02582.14 GAN07631.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Adaptin_N PF01602.20 GAN07632.1 - 4.7e-55 187.1 1.4 5.7e-55 186.9 1.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd3 PF12719.7 GAN07632.1 - 6.3e-06 25.6 0.2 1e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAN07632.1 - 3.1e-05 24.3 0.1 0.026 14.9 0.0 2.5 1 1 1 2 2 2 2 HEAT repeats PAP1 PF08601.10 GAN07633.1 - 2.3e-15 57.2 0.0 2.3e-15 57.2 0.0 3.2 2 1 1 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 GAN07633.1 - 4.2e-07 30.0 16.7 4.2e-07 30.0 16.7 2.2 2 1 0 2 2 2 1 bZIP transcription factor Rabaptin PF03528.15 GAN07633.1 - 0.0059 15.4 5.9 0.01 14.6 5.9 1.3 1 0 0 1 1 1 1 Rabaptin baeRF_family5 PF18846.1 GAN07633.1 - 0.012 15.9 2.0 0.012 15.9 2.0 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 Polo_box_2 PF18531.1 GAN07633.1 - 0.076 13.1 0.9 0.89 9.7 0.1 2.2 2 0 0 2 2 2 0 Polo box domain bZIP_2 PF07716.15 GAN07633.1 - 0.14 12.3 20.0 3 8.0 20.0 2.6 1 1 0 1 1 1 0 Basic region leucine zipper DUF5327 PF17261.2 GAN07633.1 - 1.1 10.0 9.2 14 6.5 4.3 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Nucleo_P87 PF07267.11 GAN07633.1 - 1.7 7.4 10.6 2.8 6.7 10.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4407 PF14362.6 GAN07633.1 - 6.2 6.1 6.8 9.4 5.5 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 GAN07634.1 - 4.9 6.9 78.1 0.85 9.4 37.5 2.8 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B RNA_pol_Rpb4 PF03874.16 GAN07635.1 - 2.4e-27 95.7 8.8 3.1e-27 95.3 8.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 HBD PF18534.1 GAN07635.1 - 0.0098 16.0 2.8 0.026 14.6 2.6 1.9 1 1 0 1 1 1 1 Helical bundle domain CopG_antitoxin PF12441.8 GAN07635.1 - 0.015 15.8 2.9 1.6 9.3 0.3 2.4 1 1 1 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system DUF5063 PF16702.5 GAN07635.1 - 0.16 12.3 3.0 0.13 12.7 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) Pkinase PF00069.25 GAN07636.1 - 7.1e-77 258.3 0.0 1.1e-76 257.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07636.1 - 2.6e-42 144.9 0.0 3.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN07636.1 - 2.3e-06 26.7 0.0 1.5e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN07636.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 GAN07636.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 GAN07636.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Thaumatin PF00314.17 GAN07637.1 - 3.9e-48 163.9 14.6 2.5e-47 161.3 14.6 1.9 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 GAN07637.1 - 0.65 9.2 5.4 3.8 6.7 1.8 2.7 2 1 0 2 2 2 0 Beta-1,3-glucanase efThoc1 PF11957.8 GAN07638.1 - 1.1e-82 278.2 0.3 2.3e-82 277.3 0.3 1.5 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Hen1_Lam_C PF18441.1 GAN07638.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 Hen1 La-motif C-terminal domain ResIII PF04851.15 GAN07638.1 - 0.024 14.6 0.4 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit POT1 PF02765.17 GAN07639.1 - 2e-09 37.4 0.1 8.3e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 GAN07639.1 - 1.3e-08 34.9 1.9 1.7e-06 28.0 0.0 3.4 3 1 0 3 3 3 1 ssDNA-binding domain of telomere protection protein WYL PF13280.6 GAN07639.1 - 0.047 13.7 0.1 0.42 10.6 0.1 2.4 2 1 0 2 2 2 0 WYL domain DUF1804 PF08822.11 GAN07640.1 - 0.035 14.1 1.0 0.053 13.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) HTH_23 PF13384.6 GAN07640.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 GAN07640.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Cas_Cas6 PF01881.16 GAN07640.1 - 0.73 10.4 4.1 0.93 10.0 3.2 1.7 1 1 0 1 1 1 0 CRISPR associated protein Cas6 DUF2408 PF10303.9 GAN07642.1 - 5.1e-41 140.4 11.5 4e-21 76.0 5.0 4.8 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Med9 PF07544.13 GAN07642.1 - 0.00083 19.4 8.6 0.065 13.3 0.3 4.0 4 0 0 4 4 4 2 RNA polymerase II transcription mediator complex subunit 9 DUF4254 PF14063.6 GAN07642.1 - 0.006 16.4 0.6 1.1 9.0 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4254) TACC_C PF05010.14 GAN07642.1 - 0.017 14.9 1.6 0.017 14.9 1.6 1.8 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2087 PF09860.9 GAN07642.1 - 0.027 14.6 0.7 12 6.1 0.0 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) EzrA PF06160.12 GAN07642.1 - 0.03 12.5 8.0 0.27 9.4 1.8 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 GAN07642.1 - 0.074 13.5 13.2 2.4 8.6 2.9 4.4 4 1 0 4 4 3 0 Snapin/Pallidin Apolipoprotein PF01442.18 GAN07642.1 - 0.098 12.5 4.6 0.12 12.2 2.6 2.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4435 PF14491.6 GAN07642.1 - 0.098 12.5 1.5 0.24 11.3 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) Spc7 PF08317.11 GAN07642.1 - 0.11 11.3 10.8 0.48 9.3 10.8 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3958 PF13125.6 GAN07642.1 - 0.15 12.3 3.4 0.46 10.7 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) Prominin PF05478.11 GAN07642.1 - 0.25 9.3 6.3 0.37 8.7 6.3 1.3 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.9 GAN07642.1 - 0.63 10.4 5.9 5.7 7.3 0.4 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IZUMO PF15005.6 GAN07642.1 - 0.93 10.0 5.6 17 5.9 0.5 2.9 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Cortex-I_coil PF09304.10 GAN07642.1 - 0.99 9.6 8.2 3 8.1 2.4 2.7 2 0 0 2 2 2 0 Cortexillin I, coiled coil FapA PF03961.13 GAN07642.1 - 1 7.9 7.2 4.7 5.7 7.1 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A SesA PF17107.5 GAN07642.1 - 3.6 7.8 6.3 14 5.9 0.2 3.5 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YscO PF07321.12 GAN07642.1 - 8.4 6.3 7.9 20 5.1 0.8 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO Seryl_tRNA_N PF02403.22 GAN07642.1 - 9.8 6.5 10.2 2.8 8.2 3.8 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Med13_C PF06333.12 GAN07643.1 - 1.8e-44 152.4 0.1 1.8e-44 152.4 0.1 3.3 2 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 GAN07643.1 - 1.7e-24 86.9 0.4 1.7e-24 86.9 0.4 3.9 3 1 0 3 3 3 1 MID domain of medPIWI Med13_N PF11597.8 GAN07643.1 - 2.4e-08 33.7 1.9 2.4e-08 33.7 1.9 2.4 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal BAR PF03114.18 GAN07644.1 - 2.2e-48 165.0 0.3 2.7e-48 164.7 0.3 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAN07644.1 - 0.00015 21.5 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 BAR domain of APPL family SHE3 PF17078.5 GAN07644.1 - 0.00082 19.1 2.4 0.42 10.3 0.3 3.0 1 1 2 3 3 3 3 SWI5-dependent HO expression protein 3 Arfaptin PF06456.13 GAN07644.1 - 0.0011 18.6 2.7 0.014 15.0 2.7 2.1 1 1 0 1 1 1 1 Arfaptin-like domain GerPC PF10737.9 GAN07644.1 - 0.022 14.8 0.5 6 6.9 0.1 2.6 3 0 0 3 3 3 0 Spore germination protein GerPC FeoB_Cyto PF17910.1 GAN07644.1 - 0.081 13.5 2.4 1.1 9.8 0.1 2.8 2 0 0 2 2 2 0 FeoB cytosolic helical domain TANGO2 PF05742.12 GAN07645.1 - 2.5e-61 207.9 0.0 3.1e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Arb1 PF09692.10 GAN07646.1 - 2.2e-47 162.1 0.6 4.6e-42 144.6 0.0 2.2 1 1 1 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 MBOAT_2 PF13813.6 GAN07646.1 - 1.1e-05 25.6 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PXB PF12828.7 GAN07646.1 - 0.093 12.7 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 PX-associated Pyrophosphatase PF00719.19 GAN07647.1 - 9.5e-53 178.3 0.6 1.3e-52 177.8 0.6 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase TPR_1 PF00515.28 GAN07648.1 - 4e-13 48.6 7.0 1.9e-07 30.6 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN07648.1 - 5.9e-11 41.9 2.3 1.1e-05 25.1 0.1 3.7 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 GAN07648.1 - 1e-09 37.7 7.9 5e-05 23.1 0.2 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN07648.1 - 5.6e-08 33.0 0.3 1.7e-07 31.4 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN07648.1 - 2.1e-07 30.5 0.3 0.001 19.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN07648.1 - 6e-07 29.2 3.2 0.027 14.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN07648.1 - 9.1e-07 29.3 0.7 2.2e-06 28.1 0.7 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07648.1 - 1.7e-06 28.4 0.6 0.072 13.9 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN07648.1 - 4.4e-05 23.5 0.5 0.0044 17.1 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN07648.1 - 0.00029 21.4 2.4 0.0042 17.7 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAN07648.1 - 0.0013 18.8 6.9 0.0041 17.2 0.3 3.7 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 GAN07648.1 - 0.0058 16.5 1.0 3.7 7.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF5113 PF17140.4 GAN07648.1 - 0.0083 16.0 2.1 0.026 14.3 1.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF5113) TPR_6 PF13174.6 GAN07648.1 - 0.016 15.8 6.6 8.6 7.2 0.1 4.0 4 1 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN07648.1 - 0.027 14.7 1.5 0.027 14.7 1.5 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3887 PF13026.6 GAN07648.1 - 0.11 13.4 5.7 0.28 12.0 0.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) TPR_17 PF13431.6 GAN07648.1 - 0.11 12.9 0.3 31 5.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 GAN07649.1 - 9.7e-22 76.5 11.2 1.8e-21 75.7 11.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 GAN07649.1 - 1.3e-08 34.5 0.1 3.3e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 GAN07649.1 - 1.1e-06 28.4 8.6 1.9e-06 27.6 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN07649.1 - 0.00054 19.8 9.7 0.032 14.1 9.8 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN07649.1 - 0.0019 18.5 12.1 0.0036 17.6 12.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN07649.1 - 0.091 12.6 11.2 0.17 11.8 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 GAN07649.1 - 0.29 11.3 3.0 0.75 10.0 3.0 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 GAN07649.1 - 0.56 10.1 11.2 1 9.3 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAM83 PF07894.12 GAN07649.1 - 2.7 7.5 17.2 8 5.9 0.7 2.7 2 0 0 2 2 2 0 FAM83 A-H Ipi1_N PF12333.8 GAN07650.1 - 1.8e-21 76.7 0.7 1.8e-21 76.7 0.7 2.4 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DUF2281 PF10047.9 GAN07650.1 - 0.14 12.9 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) BolA PF01722.18 GAN07651.1 - 3.3e-30 104.2 2.5 3.3e-30 104.2 2.5 1.5 2 0 0 2 2 2 1 BolA-like protein Sod_Fe_N PF00081.22 GAN07651.1 - 0.021 15.3 3.7 0.12 12.9 2.7 2.2 2 1 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain MFS_3 PF05977.13 GAN07651.1 - 0.17 10.2 0.0 0.17 10.2 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Ribosomal_L1 PF00687.21 GAN07652.1 - 3.6e-38 131.3 4.0 4.5e-38 131.1 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RNA_pol_Rpb8 PF03870.15 GAN07653.1 - 7.1e-52 175.3 0.1 8e-52 175.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Snf7 PF03357.21 GAN07654.1 - 8.3e-44 149.2 25.7 1.2e-43 148.7 25.7 1.2 1 0 0 1 1 1 1 Snf7 Peptidase_M2 PF01401.18 GAN07654.1 - 0.61 8.6 7.8 0.76 8.3 7.8 1.0 1 0 0 1 1 1 0 Angiotensin-converting enzyme FapA PF03961.13 GAN07654.1 - 9.6 4.7 11.5 6.4 5.3 9.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Rhodanese PF00581.20 GAN07655.1 - 1.3e-10 41.8 0.0 1.6e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Dot_icm_IcmQ PF09475.10 GAN07655.1 - 0.017 14.6 0.1 0.049 13.1 0.1 1.7 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DDE_3 PF13358.6 GAN07656.1 - 7.4e-21 74.4 0.0 1.7e-19 70.0 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 GAN07657.1 - 7.6e-61 205.8 0.2 6.9e-53 179.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07657.1 - 1.1e-33 116.6 0.1 9.5e-30 103.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN07657.1 - 2e-09 37.2 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF3263 PF11662.8 GAN07657.1 - 0.0015 18.3 0.0 0.0058 16.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3263) Pox_ser-thr_kin PF05445.11 GAN07657.1 - 0.0096 14.9 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 GAN07657.1 - 0.029 14.3 0.5 0.076 12.9 0.4 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family ENT PF03735.14 GAN07657.1 - 0.077 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 ENT domain Pkinase_fungal PF17667.1 GAN07657.1 - 0.091 11.5 3.4 0.11 11.3 0.1 2.4 2 1 0 3 3 3 0 Fungal protein kinase zf-C2H2 PF00096.26 GAN07658.1 - 5.1e-11 42.4 13.5 2e-05 24.8 4.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN07658.1 - 4.2e-10 39.6 19.7 1.4e-05 25.3 4.9 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN07658.1 - 3.6e-05 24.3 14.9 0.011 16.5 1.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 GAN07658.1 - 0.013 15.9 1.0 2.8 8.5 0.2 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain FOXP-CC PF16159.5 GAN07658.1 - 0.028 15.1 0.1 0.028 15.1 0.1 2.9 3 1 1 4 4 2 0 FOXP coiled-coil domain DUF1644 PF07800.12 GAN07658.1 - 0.063 13.3 8.2 0.11 12.6 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) zf-C2H2_3rep PF18868.1 GAN07658.1 - 0.064 13.9 4.1 6.6 7.4 1.3 2.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF5427 PF10310.9 GAN07658.1 - 0.12 11.3 6.9 0.14 11.1 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) zf-H2C2_5 PF13909.6 GAN07658.1 - 0.21 11.3 11.8 0.47 10.3 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 GAN07658.1 - 0.49 10.7 3.9 1.2 9.5 3.8 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 GAN07658.1 - 2.1 8.8 8.6 0.49 10.7 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RNase_PH PF01138.21 GAN07659.1 - 3.7e-24 85.7 0.0 6.3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAN07659.1 - 1.8e-08 34.3 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MFS_1_like PF12832.7 GAN07660.1 - 1.1e-72 245.1 7.9 1.4e-72 244.7 7.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAN07660.1 - 5.3e-20 71.6 53.9 1.6e-10 40.5 10.5 3.9 1 1 3 4 4 4 4 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAN07660.1 - 3.6e-16 59.1 3.2 3.6e-16 59.1 3.2 2.4 2 1 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 GAN07660.1 - 2.3e-06 26.6 3.9 2.3e-06 26.6 3.9 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter OATP PF03137.20 GAN07660.1 - 0.021 13.2 0.1 0.021 13.2 0.1 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 GAN07660.1 - 0.023 13.3 22.9 0.11 11.1 8.7 3.1 3 1 0 3 3 3 0 MFS/sugar transport protein ATG22 PF11700.8 GAN07660.1 - 0.7 8.5 23.0 0.82 8.2 11.1 3.4 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like WD40 PF00400.32 GAN07662.1 - 9e-30 102.3 4.2 4.6e-08 33.6 0.1 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07662.1 - 5.5e-15 55.4 0.2 0.00012 22.3 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 GAN07662.1 - 5.8e-09 35.4 0.7 1.3e-08 34.4 0.7 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 GAN07662.1 - 3e-08 32.8 0.5 0.00067 18.4 0.1 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN07662.1 - 5.1e-08 32.3 1.6 0.066 12.2 0.1 4.1 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAN07662.1 - 0.00012 22.1 0.1 0.068 13.0 0.0 3.4 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 GAN07662.1 - 0.13 11.2 0.6 2.6 6.9 0.0 2.7 1 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain hnRNP_Q_AcD PF18360.1 GAN07662.1 - 0.13 12.2 0.1 0.39 10.7 0.1 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain ORC2 PF04084.14 GAN07663.1 - 1.3e-116 389.2 0.3 1.5e-115 385.7 0.0 2.2 2 0 0 2 2 2 1 Origin recognition complex subunit 2 Cwf_Cwc_15 PF04889.12 GAN07663.1 - 0.59 9.8 31.3 0.24 11.1 19.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ion_trans PF00520.31 GAN07664.1 - 9e-11 41.5 18.6 1.7e-10 40.5 18.6 1.5 1 0 0 1 1 1 1 Ion transport protein Baculo_11_kDa PF06143.11 GAN07664.1 - 3.2 7.4 6.6 0.77 9.4 0.5 2.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family Cofilin_ADF PF00241.20 GAN07665.1 - 9e-22 77.1 0.0 1e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CPDase PF07823.11 GAN07666.1 - 0.026 14.2 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 GAN07666.1 - 0.041 13.8 0.1 5.1 7.0 0.1 2.9 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily OAR PF03826.17 GAN07666.1 - 0.21 11.5 0.6 0.41 10.5 0.6 1.5 1 0 0 1 1 1 0 OAR domain DUF4119 PF13494.6 GAN07667.1 - 0.016 15.3 0.1 0.046 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Adaptin_N PF01602.20 GAN07667.1 - 0.028 13.0 4.3 0.23 10.0 4.9 1.8 1 1 1 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.6 GAN07667.1 - 0.081 13.3 0.0 1.2 9.6 0.0 2.2 1 1 1 2 2 2 0 HEAT repeats DUF4476 PF14771.6 GAN07667.1 - 0.09 13.1 0.5 5 7.5 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4476) DUF3698 PF12479.8 GAN07667.1 - 0.099 13.2 1.1 11 6.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3698) PPR_3 PF13812.6 GAN07668.1 - 1e-27 96.0 0.4 2.4e-06 27.5 0.0 6.0 5 1 0 6 6 6 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAN07668.1 - 1.9e-24 85.6 3.3 0.00016 21.8 0.0 7.9 4 3 5 9 9 9 5 PPR repeat family PPR_long PF17177.4 GAN07668.1 - 8.4e-19 67.8 1.3 9.8e-06 25.1 0.6 4.2 2 2 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAN07668.1 - 3.3e-16 58.3 6.6 0.00028 20.9 0.0 8.0 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.7 GAN07668.1 - 3.7e-08 32.9 0.3 0.005 16.5 0.0 4.9 5 0 0 5 5 5 1 PPR repeat TPR_12 PF13424.6 GAN07668.1 - 0.024 14.9 0.8 36 4.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AEP1 PF17049.5 GAN07668.1 - 0.06 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase expression protein 1 IucA_IucC PF04183.12 GAN07669.1 - 4.7e-25 88.5 0.0 1.5e-24 86.9 0.0 1.8 2 0 0 2 2 2 1 IucA / IucC family FhuF PF06276.12 GAN07669.1 - 2.3e-14 54.1 0.3 2.4e-13 50.8 0.0 2.4 3 0 0 3 3 3 1 Ferric iron reductase FhuF-like transporter DUF5588 PF17826.1 GAN07670.1 - 0.0074 15.2 0.1 0.0082 15.1 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) 14-3-3 PF00244.20 GAN07671.1 - 2.8e-106 354.0 6.2 3.2e-106 353.8 6.2 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 GAN07671.1 - 0.052 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF PQ-loop PF04193.14 GAN07672.1 - 1.7e-14 53.3 0.2 4e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 PQ loop repeat Glyco_trans_1_4 PF13692.6 GAN07672.1 - 0.01 16.2 0.0 0.047 14.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 NDK PF00334.19 GAN07673.1 - 4.4e-32 110.9 0.0 5.4e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Rtt106 PF08512.12 GAN07673.1 - 0.12 12.8 0.2 0.36 11.3 0.2 2.0 1 1 0 1 1 1 0 Histone chaperone Rttp106-like Cullin_binding PF03556.15 GAN07674.1 - 7.7e-29 100.6 6.1 1.5e-28 99.7 6.1 1.5 1 0 0 1 1 1 1 Cullin binding Glycogen_syn PF05693.13 GAN07675.1 - 0 1100.1 0.0 0 1099.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 GAN07675.1 - 2.7e-07 30.6 0.0 6.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GAN07675.1 - 9.4e-07 28.5 0.0 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN07675.1 - 1.9e-06 28.3 0.0 0.0032 17.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN07675.1 - 2.3e-05 24.5 0.1 4.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAN07675.1 - 0.0038 17.7 0.0 0.0081 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Sec61_beta PF03911.16 GAN07676.1 - 6.9e-18 64.4 0.7 8.3e-18 64.1 0.7 1.1 1 0 0 1 1 1 1 Sec61beta family adh_short_C2 PF13561.6 GAN07677.1 - 9.3e-44 149.7 0.4 4.9e-43 147.3 0.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN07677.1 - 3.1e-42 144.3 0.1 2.1e-41 141.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN07677.1 - 0.0027 17.7 0.1 0.0052 16.7 0.1 1.6 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 GAN07677.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent E1-E2_ATPase PF00122.20 GAN07678.1 - 7.6e-48 162.4 1.5 7.6e-48 162.4 1.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN07678.1 - 1.8e-21 76.7 13.3 2.2e-15 56.9 3.1 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAN07678.1 - 5.4e-20 71.3 0.0 1.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN07678.1 - 9.3e-17 62.0 0.3 3.3e-14 53.7 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN07678.1 - 4.3e-13 48.8 0.0 9.9e-13 47.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN07678.1 - 0.00012 21.9 1.1 0.054 13.2 0.6 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3504 PF12012.8 GAN07678.1 - 0.17 11.8 0.4 0.4 10.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Polysacc_deac_1 PF01522.21 GAN07679.1 - 1.5e-23 83.1 0.0 2.8e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN07679.1 - 1.2e-05 24.7 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF4159 PF13709.6 GAN07679.1 - 0.064 12.7 0.4 0.49 9.8 0.0 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4159) RNA_pol_Rpb2_6 PF00562.28 GAN07680.1 - 7.7e-113 377.5 1.2 7.7e-113 377.5 1.2 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAN07680.1 - 3.5e-32 111.6 0.0 3.5e-32 111.6 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 GAN07680.1 - 3.9e-27 94.2 0.0 1.1e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 GAN07680.1 - 2e-23 82.1 0.0 4.4e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 GAN07680.1 - 3.3e-23 81.9 0.1 9.9e-23 80.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAN07680.1 - 1.4e-21 77.0 0.0 1.4e-21 77.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 Sugar_tr PF00083.24 GAN07681.1 - 8.5e-119 397.4 26.6 3.5e-89 299.7 17.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN07681.1 - 2.2e-36 125.5 19.7 2.2e-36 125.5 19.7 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAN07681.1 - 1.3e-06 27.2 3.5 1.3e-06 27.2 3.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 GAN07681.1 - 2.7e-05 22.9 17.6 8.4e-05 21.3 3.5 3.7 3 1 1 4 4 4 2 MFS/sugar transport protein PSI PF01437.25 GAN07681.1 - 6.6e-05 23.4 3.7 0.00011 22.6 3.7 1.3 1 0 0 1 1 1 1 Plexin repeat MFS_3 PF05977.13 GAN07681.1 - 0.00043 18.8 14.7 0.00065 18.2 3.8 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 GAN07681.1 - 0.033 13.0 18.7 0.0075 15.2 3.0 2.9 2 1 1 3 3 3 0 MFS_1 like family Phage_holin_3_2 PF04550.12 GAN07681.1 - 1.1 9.9 7.7 4.1 8.0 2.6 3.0 2 0 0 2 2 2 0 Phage holin family 2 DnaJ_C PF01556.18 GAN07682.1 - 1.2e-36 126.0 0.0 1.7e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN07682.1 - 2.2e-26 91.7 5.2 2.2e-26 91.7 5.2 2.3 3 0 0 3 3 3 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAN07682.1 - 1.6e-09 38.0 19.2 3.1e-09 37.0 19.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 GAN07682.1 - 0.0012 18.8 1.0 0.0012 18.8 1.0 2.6 2 0 0 2 2 2 1 Cytochrome c7 and related cytochrome c DUF4811 PF16069.5 GAN07682.1 - 0.49 10.3 4.9 0.73 9.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) HypA PF01155.19 GAN07682.1 - 0.9 9.6 10.0 1.1 9.3 1.5 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 GAN07682.1 - 4.5 7.3 15.2 5.1 7.1 2.1 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Gp_dh_C PF02800.20 GAN07684.1 - 1.2e-70 236.2 0.0 1.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAN07684.1 - 2.7e-39 133.6 0.0 7.5e-39 132.2 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAN07684.1 - 0.051 13.7 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus AAA_32 PF13654.6 GAN07686.1 - 0.0025 16.7 2.5 0.0027 16.6 2.5 1.0 1 0 0 1 1 1 1 AAA domain MRP-S26 PF14943.6 GAN07686.1 - 0.012 15.6 5.4 0.013 15.4 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PIN_10 PF18478.1 GAN07686.1 - 0.056 13.7 0.3 0.089 13.0 0.3 1.4 1 1 0 1 1 1 0 PIN like domain MAS20 PF02064.15 GAN07688.1 - 2.6e-41 140.7 2.1 2.6e-41 140.7 2.1 3.0 3 1 1 4 4 4 1 MAS20 protein import receptor zf-U1 PF06220.12 GAN07688.1 - 5.6e-08 32.4 3.6 6e-08 32.3 0.4 2.5 2 0 0 2 2 2 1 U1 zinc finger SET PF00856.28 GAN07688.1 - 3e-07 31.0 0.8 3e-07 31.0 0.8 3.1 3 1 0 3 3 3 1 SET domain zf-MYND PF01753.18 GAN07688.1 - 0.00056 20.0 10.4 0.00056 20.0 10.4 2.0 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 GAN07688.1 - 0.023 14.8 9.2 0.09 12.9 9.2 2.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-FLZ PF04570.14 GAN07688.1 - 0.2 11.2 8.5 0.063 12.8 4.4 2.2 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Myb_DNA-bind_7 PF15963.5 GAN07688.1 - 0.24 11.3 4.8 1.3 9.0 4.8 2.2 1 0 0 1 1 1 0 Myb DNA-binding like YtxH PF12732.7 GAN07688.1 - 0.59 10.7 4.5 0.8 10.3 1.9 2.5 2 0 0 2 2 2 0 YtxH-like protein USP8_interact PF08941.10 GAN07688.1 - 0.62 9.9 2.6 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 USP8 interacting C1_1 PF00130.22 GAN07688.1 - 5 7.1 9.9 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 GAN07689.1 - 1.7e-67 227.5 0.0 5.3e-67 226.0 0.0 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07689.1 - 3.8e-39 134.5 0.0 1.1e-38 133.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ribosomal_L2 PF00181.23 GAN07689.1 - 5.1e-15 55.2 0.5 1.2e-14 54.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Kdo PF06293.14 GAN07689.1 - 7.7e-05 22.1 0.1 0.00018 20.9 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN07689.1 - 0.00054 20.0 0.0 0.0091 15.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAN07689.1 - 0.0015 18.1 0.1 0.0033 17.0 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 GAN07689.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Archaeal_AmoA PF12942.7 GAN07690.1 - 0.069 12.8 0.2 0.47 10.1 0.0 1.9 1 1 1 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) COPIIcoated_ERV PF07970.12 GAN07691.1 - 1.1e-39 136.5 0.6 1.6e-39 136.0 0.6 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAN07691.1 - 8e-20 71.0 0.1 1.6e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AAA PF00004.29 GAN07692.1 - 1.5e-44 151.7 0.3 4.9e-44 149.9 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN07692.1 - 6.9e-11 41.8 0.1 1.6e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAN07692.1 - 2.2e-09 37.1 0.2 2.3e-08 33.9 0.0 2.6 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 GAN07692.1 - 3.9e-09 36.6 0.1 1.1e-08 35.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAN07692.1 - 6.4e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAN07692.1 - 7.7e-08 32.9 0.2 2.1e-05 25.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 GAN07692.1 - 9.3e-06 25.0 0.0 1.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAN07692.1 - 0.00012 22.3 1.3 0.016 15.5 1.3 2.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 GAN07692.1 - 0.00016 21.7 0.1 0.016 15.2 0.0 2.6 2 1 1 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GAN07692.1 - 0.00023 21.7 0.0 0.00064 20.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 GAN07692.1 - 0.00041 20.1 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GAN07692.1 - 0.00061 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAN07692.1 - 0.0015 18.6 0.0 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN07692.1 - 0.0021 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 GAN07692.1 - 0.0022 17.8 0.1 0.0066 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 GAN07692.1 - 0.0024 17.8 0.4 0.01 15.8 0.0 2.3 3 0 0 3 3 2 1 NTPase TIP49 PF06068.13 GAN07692.1 - 0.0028 16.9 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 GAN07692.1 - 0.004 16.7 0.1 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 GAN07692.1 - 0.0051 17.0 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 GAN07692.1 - 0.0086 15.5 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAN07692.1 - 0.0097 15.7 0.1 0.023 14.5 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein NACHT PF05729.12 GAN07692.1 - 0.011 15.7 0.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 GAN07692.1 - 0.011 15.4 0.5 0.049 13.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 GAN07692.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAN07692.1 - 0.015 14.7 0.0 0.67 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 GAN07692.1 - 0.021 14.6 0.1 0.048 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAN07692.1 - 0.029 14.2 0.1 0.093 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAN07692.1 - 0.03 13.7 1.2 0.55 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 GAN07692.1 - 0.032 14.8 0.2 0.47 11.0 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 GAN07692.1 - 0.047 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAN07692.1 - 0.075 12.7 0.2 1.3 8.7 0.0 2.7 3 1 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 GAN07692.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4972 PF16342.5 GAN07692.1 - 0.5 10.1 2.9 2.2 8.0 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) Ribosomal_S3Ae PF01015.18 GAN07693.1 - 1.5e-10 41.0 0.1 1.8e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family F-box-like PF12937.7 GAN07694.1 - 8.9e-13 47.9 0.6 8.9e-13 47.9 0.6 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN07694.1 - 8.5e-06 25.5 0.1 2.1e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 GAN07694.1 - 0.14 11.8 0.1 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 F-box IQ PF00612.27 GAN07695.1 - 2.1e-05 23.9 0.1 4.9e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Suf PF05843.14 GAN07695.1 - 0.0029 17.6 15.6 0.0055 16.7 15.6 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Lin-8 PF03353.15 GAN07695.1 - 0.0042 16.7 9.0 0.0042 16.7 9.0 3.0 3 1 0 3 3 3 1 Ras-mediated vulval-induction antagonist Sugarporin_N PF11471.8 GAN07695.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.2 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Jnk-SapK_ap_N PF09744.9 GAN07695.1 - 5.6 7.2 24.0 1.1 9.4 12.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CREPT PF16566.5 GAN07695.1 - 9 6.5 20.2 2.3 8.4 12.6 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour MFS_1 PF07690.16 GAN07696.1 - 2e-23 82.9 33.9 2e-23 82.9 33.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2749 PF10907.8 GAN07696.1 - 1.1 9.5 3.2 31 4.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) CSN8_PSD8_EIF3K PF10075.9 GAN07697.1 - 5.3e-18 65.4 0.8 7.3e-18 64.9 0.8 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 GAN07697.1 - 0.0055 17.2 0.9 0.014 15.9 0.9 1.8 1 1 0 1 1 1 1 PCI domain HTH_37 PF13744.6 GAN07697.1 - 0.071 13.1 0.3 8.5 6.4 0.0 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain DUF1394 PF07159.12 GAN07698.1 - 8.3e-108 360.2 0.0 9.4e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF2990 PF11693.8 GAN07698.1 - 0.053 13.7 0.0 0.22 11.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) Ribosomal_L22 PF00237.19 GAN07699.1 - 1.5e-39 134.3 0.1 2e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L15e PF00827.17 GAN07700.1 - 7.8e-76 254.1 6.5 3.9e-75 251.8 6.5 1.8 1 1 0 1 1 1 1 Ribosomal L15 Pyr_redox_2 PF07992.14 GAN07702.1 - 2.2e-29 102.6 0.0 1.6e-26 93.3 0.1 1.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN07702.1 - 8.5e-15 55.1 0.1 3.9e-09 37.0 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 GAN07702.1 - 1.9e-10 41.1 0.3 3.3e-10 40.3 0.3 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.24 GAN07702.1 - 1.5e-06 28.0 0.3 0.13 11.9 0.0 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN07702.1 - 2.2e-06 27.8 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAN07702.1 - 0.00038 19.6 0.0 0.64 9.0 0.0 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 GAN07702.1 - 0.0011 18.1 0.1 0.51 9.4 0.1 3.7 4 0 0 4 4 4 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAN07702.1 - 0.0017 17.7 0.0 0.032 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RGS-like PF09128.11 GAN07702.1 - 0.0022 17.7 0.3 0.0042 16.8 0.3 1.4 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain ThiF PF00899.21 GAN07702.1 - 0.0034 16.8 0.0 0.056 12.8 0.1 2.2 2 0 0 2 2 2 1 ThiF family DUF1188 PF06690.11 GAN07702.1 - 0.0081 15.7 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) UDPG_MGDP_dh_N PF03721.14 GAN07702.1 - 0.018 14.6 0.2 11 5.6 0.0 3.4 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 GAN07702.1 - 0.03 13.0 0.0 6.9 5.3 0.0 3.2 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 GAN07702.1 - 0.033 13.5 0.1 4.7 6.5 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 GAN07702.1 - 0.033 13.3 0.5 11 5.0 0.0 2.9 2 2 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 GAN07702.1 - 0.065 13.5 0.1 16 5.8 0.1 2.8 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 GAN07702.1 - 0.086 12.1 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Sacchrp_dh_NADP PF03435.18 GAN07702.1 - 0.091 13.0 0.7 13 6.1 0.1 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain XdhC_C PF13478.6 GAN07702.1 - 0.13 12.8 0.0 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Shikimate_DH PF01488.20 GAN07702.1 - 0.13 12.3 1.4 8.1 6.5 0.1 3.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GAN07702.1 - 0.19 10.9 0.0 9.5 5.3 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain zf-CCCH PF00642.24 GAN07703.1 - 2.1e-07 30.7 2.8 2.1e-07 30.7 2.8 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 GAN07703.1 - 0.00035 20.3 0.1 0.00054 19.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAN07703.1 - 0.0066 16.5 2.9 0.0066 16.5 2.9 2.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 GAN07703.1 - 0.067 13.9 1.5 0.13 13.0 0.8 1.7 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 GAN07703.1 - 0.082 13.1 3.1 0.12 12.5 1.1 2.1 2 1 0 2 2 2 0 Zinc-finger containing family Ctr PF04145.15 GAN07705.1 - 3.9e-28 98.9 0.1 5.9e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF3494 PF11999.8 GAN07705.1 - 0.027 14.1 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) Aminotran_1_2 PF00155.21 GAN07706.1 - 1.9e-22 79.9 0.0 2.4e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAN07706.1 - 2.3e-09 36.6 0.0 3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase F-box-like PF12937.7 GAN07709.1 - 5.9e-06 26.1 1.1 8.9e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 GAN07709.1 - 0.066 13.9 2.5 99 3.9 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Sad1_UNC PF07738.13 GAN07710.1 - 1.7e-26 92.8 0.0 6.7e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal B2-adapt-app_C PF09066.10 GAN07710.1 - 0.0043 17.1 2.1 0.012 15.7 2.0 1.8 1 1 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain MMPL PF03176.15 GAN07710.1 - 0.0043 16.0 0.7 0.007 15.3 0.7 1.3 1 0 0 1 1 1 1 MMPL family Fmp27_SW PF10305.9 GAN07710.1 - 0.098 13.4 2.9 0.13 12.9 1.5 2.1 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Fic PF02661.18 GAN07710.1 - 0.46 11.4 2.5 1.1 10.2 0.9 2.4 1 1 1 2 2 2 0 Fic/DOC family DUF892 PF05974.12 GAN07710.1 - 0.54 10.3 5.0 0.69 9.9 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF507 PF04368.13 GAN07710.1 - 0.65 9.9 9.3 8.9 6.2 9.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF507) COG2 PF06148.11 GAN07710.1 - 1.3 9.1 6.6 0.43 10.7 1.0 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_Mu_Gam PF07352.12 GAN07710.1 - 2.7 7.9 7.2 0.41 10.5 0.2 2.6 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein AAA_11 PF13086.6 GAN07711.1 - 1.3e-65 221.8 0.6 1.3e-65 221.8 0.6 3.2 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 GAN07711.1 - 5.1e-62 209.0 0.0 1.2e-61 207.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 GAN07711.1 - 4.8e-60 203.6 15.7 7.3e-60 203.1 15.7 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_30 PF13604.6 GAN07711.1 - 5e-11 42.7 0.1 3e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAN07711.1 - 3.4e-10 40.4 0.0 1.3e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 GAN07711.1 - 1e-05 25.2 10.1 3e-05 23.7 0.0 3.8 3 1 1 4 4 4 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 GAN07711.1 - 0.0045 17.0 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAN07711.1 - 0.018 15.3 0.0 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAN07711.1 - 0.021 15.3 0.0 0.061 13.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TauD PF02668.16 GAN07713.1 - 8.2e-36 124.2 0.2 1.1e-35 123.7 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 GAN07713.1 - 1.7e-19 70.2 0.7 3.5e-19 69.2 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 GAN07713.1 - 0.0011 18.2 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 CsiD Rhodanese PF00581.20 GAN07714.1 - 5.7e-13 49.3 0.0 8.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain G-alpha PF00503.20 GAN07715.1 - 1.5e-100 336.8 7.9 1.9e-100 336.5 7.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN07715.1 - 8.1e-12 44.9 0.8 1.1e-10 41.2 0.3 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family SMP_C2CD2L PF18696.1 GAN07715.1 - 0.017 14.9 0.3 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain PMT PF02366.18 GAN07716.1 - 1.3e-80 270.5 14.6 2.6e-80 269.5 14.6 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAN07716.1 - 2.5e-58 197.0 15.8 2.5e-58 197.0 15.8 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAN07716.1 - 7.2e-31 107.5 1.6 1.2e-30 106.8 1.6 1.2 1 0 0 1 1 1 1 MIR domain zf-C2H2 PF00096.26 GAN07717.1 - 0.0016 18.8 4.5 0.0016 18.8 4.5 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN07717.1 - 0.069 14.0 4.4 0.21 12.5 4.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger NOA36 PF06524.12 GAN07717.1 - 0.88 8.8 12.6 1.4 8.1 12.6 1.3 1 0 0 1 1 1 0 NOA36 protein VIT PF08487.10 GAN07717.1 - 0.9 9.8 4.8 4.6 7.5 1.1 2.8 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain Cwf_Cwc_15 PF04889.12 GAN07717.1 - 1.2 8.9 21.8 0.09 12.5 16.7 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MscS_TM PF12794.7 GAN07717.1 - 1.3 7.8 9.3 0.4 9.5 6.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 TFIIA PF03153.13 GAN07717.1 - 7.3 6.5 21.5 14 5.6 21.5 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 GAN07717.1 - 8.5 4.5 12.1 11 4.2 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 GAN07718.1 - 2e-06 27.6 0.1 7.5e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN07718.1 - 3.2e-05 23.7 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain Npa1 PF11707.8 GAN07719.1 - 9.6e-95 317.8 0.1 5.5e-94 315.3 0.0 2.4 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 GAN07719.1 - 2.3e-53 180.8 0.3 2.3e-53 180.8 0.3 3.8 5 0 0 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 GAN07719.1 - 0.023 15.4 0.1 0.21 12.3 0.0 2.5 2 0 0 2 2 2 0 Creb binding TipAS PF07739.13 GAN07719.1 - 4.1 8.0 5.2 14 6.3 1.2 3.5 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Pept_tRNA_hydro PF01195.19 GAN07720.1 - 2e-43 148.3 0.1 2.5e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Cpn60_TCP1 PF00118.24 GAN07721.1 - 9.1e-169 562.2 3.9 1.1e-168 561.8 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sacchrp_dh_NADP PF03435.18 GAN07722.1 - 2e-12 47.5 0.0 3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF2929 PF11151.8 GAN07722.1 - 0.15 12.4 0.6 0.33 11.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) RepL PF05732.11 GAN07723.1 - 0.028 13.9 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Transferase PF02458.15 GAN07724.1 - 1.1e-33 116.6 0.0 1.3e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 GAN07724.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 Condensation domain Glyco_transf_8 PF01501.20 GAN07725.1 - 1.6e-19 70.5 0.7 2.6e-19 69.8 0.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF2012 PF09430.10 GAN07726.1 - 2.4e-29 102.0 0.1 3.6e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 GAN07726.1 - 2.4e-07 30.4 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 GAN07726.1 - 0.00049 20.3 0.0 0.00075 19.7 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 GAN07726.1 - 0.0022 17.9 0.1 0.0032 17.4 0.1 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain TMC PF07810.13 GAN07726.1 - 0.033 14.8 0.2 0.069 13.7 0.2 1.5 1 0 0 1 1 1 0 TMC domain Lipase_3 PF01764.25 GAN07727.1 - 2.1e-14 53.6 0.1 3.4e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) TauD PF02668.16 GAN07728.1 - 2e-51 175.4 0.2 3e-51 174.8 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 GAN07728.1 - 2.2e-10 41.0 0.3 1.3e-09 38.6 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 GAN07728.1 - 0.0069 15.5 0.0 0.01 15.0 0.0 1.4 1 1 0 1 1 1 1 CsiD Methyltransf_23 PF13489.6 GAN07729.1 - 3.2e-18 66.1 0.0 4.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN07729.1 - 3.4e-17 63.0 0.0 9.8e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN07729.1 - 5.5e-15 55.9 0.0 1.5e-14 54.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN07729.1 - 1.9e-13 50.9 0.0 3.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN07729.1 - 2.5e-09 37.1 0.1 3.8e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN07729.1 - 1.2e-07 31.3 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAN07729.1 - 2.9e-06 26.9 0.0 6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 GAN07729.1 - 0.00035 20.3 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 GAN07729.1 - 0.00036 20.1 0.0 0.0016 17.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.11 GAN07729.1 - 0.017 14.8 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 GAN07729.1 - 0.017 14.0 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DOT1 PF08123.13 GAN07729.1 - 0.02 14.4 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 tRNA_U5-meth_tr PF05958.11 GAN07729.1 - 0.027 13.5 1.5 0.094 11.7 0.0 2.0 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_2 PF00891.18 GAN07729.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Cyclin PF08613.11 GAN07730.1 - 3.8e-35 121.6 0.1 7.8e-35 120.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN07730.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Interferon PF00143.19 GAN07730.1 - 0.12 12.6 0.3 7.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Interferon alpha/beta domain UL73_N PF12522.8 GAN07730.1 - 0.37 10.6 7.2 0.71 9.7 7.2 1.4 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Lipase_3 PF01764.25 GAN07731.1 - 5.2e-17 62.0 0.0 8e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Trp_syntA PF00290.20 GAN07732.1 - 3.6e-95 317.7 0.3 3.6e-95 317.7 0.3 1.4 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 GAN07732.1 - 3.6e-49 167.8 0.5 6.1e-49 167.0 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lipase_GDSL PF00657.22 GAN07733.1 - 6.1e-16 59.0 0.0 8.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN07733.1 - 6.9e-12 46.1 0.0 5.3e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GASA PF02704.14 GAN07733.1 - 0.0057 16.8 3.2 0.0088 16.2 0.3 2.5 3 0 0 3 3 3 1 Gibberellin regulated protein AHJR-like PF18743.1 GAN07733.1 - 0.059 12.9 0.0 10 5.7 0.0 2.5 3 0 0 3 3 3 0 REase_AHJR-like Ribonuc_red_lgC PF02867.15 GAN07734.1 - 7.1e-183 608.9 0.0 1e-182 608.3 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAN07734.1 - 2.8e-24 84.9 0.0 6.7e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAN07734.1 - 9.7e-16 58.1 0.1 2.7e-15 56.7 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain Y_phosphatase2 PF03162.13 GAN07734.1 - 0.071 12.7 1.6 0.15 11.6 0.2 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Ly-6_related PF06579.12 GAN07734.1 - 0.13 12.5 0.4 0.37 11.0 0.2 1.8 2 0 0 2 2 2 0 Caenorhabditis elegans ly-6-related protein DUF2012 PF09430.10 GAN07735.1 - 0.013 15.6 0.0 1.8 8.7 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) RNA_pol_Rpb1_R PF05001.13 GAN07735.1 - 0.038 14.4 7.3 0.091 13.2 7.3 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Med15_fungi PF05397.12 GAN07735.1 - 0.053 13.8 0.3 0.16 12.3 0.3 1.8 1 0 0 1 1 1 0 Mediator complex subunit 15 DUF3381 PF11861.8 GAN07735.1 - 1.1 9.0 5.0 0.55 10.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MFS_1 PF07690.16 GAN07736.1 - 5.5e-31 107.8 40.0 5.5e-31 107.8 40.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN07736.1 - 1.6e-17 63.6 27.8 1.7e-13 50.3 8.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter WD40 PF00400.32 GAN07737.1 - 7e-32 109.0 13.6 0.00062 20.5 0.0 11.8 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07737.1 - 1e-11 45.0 0.0 0.03 14.6 0.0 6.7 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN07737.1 - 4.4e-05 23.5 0.0 0.00056 19.9 0.0 2.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A HELP PF03451.14 GAN07737.1 - 0.024 14.5 0.0 0.11 12.4 0.0 2.2 1 0 0 1 1 1 0 HELP motif Exo_endo_phos PF03372.23 GAN07739.1 - 2.3e-09 37.1 0.1 4.6e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 GAN07739.1 - 1.9e-06 27.6 17.2 0.00013 21.9 4.3 2.8 2 0 0 2 2 2 2 Zinc knuckle Exo_endo_phos_2 PF14529.6 GAN07739.1 - 4.2e-05 23.4 1.1 4.2e-05 23.4 1.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Lactamase_B_3 PF13483.6 GAN07739.1 - 0.19 11.6 1.4 3.5 7.5 0.2 3.3 4 0 0 4 4 4 0 Beta-lactamase superfamily domain MDM31_MDM32 PF08118.11 GAN07740.1 - 2.2e-109 366.5 0.0 4.4e-109 365.5 0.0 1.4 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Metallophos PF00149.28 GAN07742.1 - 1.2e-22 81.4 0.0 5.1e-21 76.1 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HECT PF00632.25 GAN07743.1 - 3.5e-68 230.4 0.0 9.6e-68 228.9 0.0 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UCH PF00443.29 GAN07744.1 - 1.6e-76 257.2 0.0 5.4e-76 255.5 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN07744.1 - 6.8e-17 62.0 1.3 3.4e-09 36.7 0.2 3.6 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAN07744.1 - 8.6e-17 61.5 0.0 8.6e-17 61.5 0.0 3.8 5 0 0 5 5 5 1 DUSP domain USP7_C2 PF14533.6 GAN07744.1 - 7.8e-06 25.7 2.8 6.1e-05 22.8 0.0 3.4 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal Ribosomal_L14e PF01929.17 GAN07745.1 - 1.9e-28 98.7 3.2 3.1e-28 98.1 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 GAN07745.1 - 0.0017 18.2 0.3 0.0032 17.4 0.3 1.5 1 0 0 1 1 1 1 KOW motif Methyltransf_23 PF13489.6 GAN07746.1 - 8.7e-17 61.4 0.0 1.6e-16 60.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN07746.1 - 3.1e-15 56.7 0.0 1.4e-14 54.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN07746.1 - 1.6e-13 51.1 0.0 4.3e-13 49.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN07746.1 - 1.3e-11 45.0 0.0 3.6e-11 43.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN07746.1 - 6e-09 35.9 0.0 1.3e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAN07746.1 - 3.5e-05 23.1 0.0 0.15 11.2 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 GAN07746.1 - 0.00057 19.3 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 GAN07746.1 - 0.0016 18.1 0.0 0.0044 16.7 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 GAN07746.1 - 0.0026 17.3 0.0 0.006 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAN07746.1 - 0.0064 15.8 0.0 0.037 13.3 0.0 2.2 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 GAN07746.1 - 0.0087 15.6 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain DUF3419 PF11899.8 GAN07746.1 - 0.0093 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.15 GAN07746.1 - 0.011 15.5 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF3298 PF11738.8 GAN07746.1 - 0.028 15.4 3.1 0.25 12.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) R3H-assoc PF13902.6 GAN07746.1 - 0.034 14.5 2.9 0.071 13.5 2.9 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain TehB PF03848.14 GAN07746.1 - 0.049 13.0 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TehB NodS PF05401.11 GAN07746.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 GAN07746.1 - 0.09 13.8 0.0 0.29 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Palm_thioest PF02089.15 GAN07749.1 - 2.5e-84 282.9 0.0 2.9e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 GAN07749.1 - 0.0085 15.6 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 GAN07749.1 - 0.029 14.0 0.0 0.096 12.3 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 GAN07749.1 - 0.046 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Pyr_redox_2 PF07992.14 GAN07750.1 - 2.4e-51 174.7 0.0 3e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN07750.1 - 2.6e-11 43.9 0.2 3.2e-10 40.4 0.0 2.6 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN07750.1 - 1.9e-05 24.1 0.6 0.1 11.8 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN07750.1 - 0.012 14.4 0.5 0.15 10.7 0.0 2.4 1 1 1 2 2 2 0 HI0933-like protein TPPII_N PF12583.8 GAN07750.1 - 0.057 14.0 0.2 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal DAO PF01266.24 GAN07750.1 - 0.12 11.9 1.2 2.8 7.4 0.3 2.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAN07750.1 - 0.7 9.9 2.2 12 5.9 0.9 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding FoP_duplication PF13865.6 GAN07751.1 - 6.6e-17 61.8 8.1 6.6e-17 61.8 8.1 2.1 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 SRP-alpha_N PF04086.13 GAN07751.1 - 0.82 9.5 7.5 1.1 9.1 7.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Cyt-b5 PF00173.28 GAN07752.1 - 1.2e-17 63.8 0.1 1.7e-16 60.1 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 GAN07752.1 - 4.1e-15 56.3 23.9 6.5e-15 55.7 23.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF1451 PF07295.11 GAN07753.1 - 0.005 16.9 9.6 3.8 7.5 0.0 4.8 3 2 1 5 5 5 3 Zinc-ribbon containing domain FliG_N PF14842.6 GAN07753.1 - 0.014 16.0 1.2 34 5.0 0.1 4.3 3 2 2 5 5 5 0 FliG N-terminal domain UBA_6 PF18039.1 GAN07753.1 - 0.055 13.4 0.2 2.3 8.2 0.0 3.0 2 0 0 2 2 2 0 UBA-like domain Peptidase_S49 PF01343.18 GAN07753.1 - 0.12 12.3 2.4 0.97 9.4 0.1 2.9 3 0 0 3 3 3 0 Peptidase family S49 FKBP_N PF01346.18 GAN07753.1 - 0.51 11.3 7.0 2.5 9.1 0.9 3.9 3 1 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PEX11 PF05648.14 GAN07754.1 - 1.3e-53 181.8 0.7 1.5e-53 181.6 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MCPVI PF02993.14 GAN07754.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Minor capsid protein VI NAD_binding_10 PF13460.6 GAN07755.1 - 1.6e-07 31.4 0.0 5.6e-07 29.6 0.0 1.8 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GAN07755.1 - 0.0068 16.0 0.0 0.019 14.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Arylesterase PF01731.20 GAN07756.1 - 2.8e-08 33.9 0.7 6.7e-08 32.6 0.7 1.6 1 0 0 1 1 1 1 Arylesterase UQ_con PF00179.26 GAN07757.1 - 1e-39 135.4 0.0 1.1e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN07757.1 - 0.0054 17.0 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 GAN07757.1 - 0.057 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF846 PF05832.12 GAN07758.1 - 1.1e-54 184.3 11.7 1.7e-54 183.6 11.7 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Halogen_Hydrol PF10112.9 GAN07758.1 - 6.1 6.8 7.6 1.3 9.0 0.9 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Zn_clus PF00172.18 GAN07759.1 - 7.1e-08 32.5 7.6 7.1e-08 32.5 7.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.23 GAN07760.1 - 2.6e-110 368.4 0.0 5.9e-110 367.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 GAN07760.1 - 8.3e-53 179.2 3.8 8.3e-53 179.2 3.8 3.0 3 0 0 3 3 3 1 Kinesin-associated DUF3694 PF12473.8 GAN07760.1 - 2.3e-42 145.3 0.2 2.1e-41 142.1 0.0 2.7 3 0 0 3 3 3 1 Kinesin protein Microtub_bd PF16796.5 GAN07760.1 - 1e-27 96.9 0.1 4.4e-27 94.8 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 GAN07760.1 - 2.5e-13 50.4 0.1 8.8e-13 48.7 0.1 2.0 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 GAN07760.1 - 1.4e-07 31.8 0.1 6e-07 29.8 0.1 2.2 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 GAN07760.1 - 1.8e-07 31.4 0.1 1.3e-06 28.7 0.1 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAN07760.1 - 0.00043 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RVT_1 PF00078.27 GAN07762.1 - 0.23 11.0 0.0 0.63 9.5 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf_Hakai PF18408.1 GAN07763.1 - 0.11 12.3 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain Arrestin_N PF00339.29 GAN07764.1 - 5.6e-07 29.7 0.6 2.7e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN07764.1 - 0.00067 20.1 0.1 0.015 15.8 0.0 3.0 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 GAN07764.1 - 0.07 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like UreD PF01774.17 GAN07765.1 - 3.1e-58 197.2 0.0 3.9e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF2398 PF09661.10 GAN07765.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) Corona_nucleoca PF00937.18 GAN07766.1 - 0.04 13.0 5.1 0.054 12.5 5.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein LMBR1 PF04791.16 GAN07766.1 - 0.11 11.4 2.5 0.13 11.1 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mem_trans PF03547.18 GAN07766.1 - 0.52 8.6 4.2 0.85 7.9 4.2 1.3 1 0 0 1 1 1 0 Membrane transport protein Herpes_capsid PF06112.11 GAN07766.1 - 1.2 9.2 12.7 0.027 14.5 5.5 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF3177 PF11375.8 GAN07766.1 - 2.9 7.6 6.0 1.8 8.3 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3177) Cyclin PF08613.11 GAN07766.1 - 7.2 7.0 8.4 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Cyclin Ribosomal_L13e PF01294.18 GAN07767.1 - 1.4e-78 262.9 4.7 1.9e-78 262.4 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e bZIP_1 PF00170.21 GAN07768.1 - 2e-11 43.8 10.0 3.1e-11 43.2 10.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN07768.1 - 9.4e-06 25.6 10.3 1.5e-05 24.9 10.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAN07768.1 - 0.031 14.8 4.6 0.065 13.8 4.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.18 GAN07768.1 - 0.061 13.6 1.1 0.11 12.7 1.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mito_carr PF00153.27 GAN07770.1 - 2.1e-66 219.9 2.8 1.1e-24 86.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glucosamine_iso PF01182.20 GAN07770.1 - 1.6e-19 70.7 0.0 2.5e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ACAS_N PF16177.5 GAN07770.1 - 0.46 10.4 2.4 1.3 9.0 2.4 1.7 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus RINGv PF12906.7 GAN07771.1 - 1e-07 31.9 10.2 1.8e-07 31.2 10.2 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 GAN07771.1 - 0.00032 20.8 5.9 0.00055 20.1 5.9 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 GAN07771.1 - 0.00095 19.4 7.6 0.0016 18.7 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 GAN07771.1 - 0.025 14.4 5.1 0.049 13.4 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 GAN07771.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_17 PF17120.5 GAN07771.1 - 0.61 9.7 4.9 1.2 8.8 4.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 GAN07771.1 - 1.6 8.7 8.2 2.6 8.0 8.2 1.4 1 0 0 1 1 1 0 PHD-finger Podoplanin PF05808.11 GAN07773.1 - 3.7e-05 23.9 2.9 6.6e-05 23.1 2.9 1.4 1 0 0 1 1 1 1 Podoplanin SPX PF03105.19 GAN07773.1 - 0.0087 16.0 10.0 0.012 15.6 10.0 1.2 1 0 0 1 1 1 1 SPX domain CD34_antigen PF06365.12 GAN07773.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family Mid2 PF04478.12 GAN07773.1 - 0.076 12.9 0.2 0.076 12.9 0.2 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Rox3 PF08633.10 GAN07773.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.5 2 1 1 3 3 3 0 Rox3 mediator complex subunit Apt1 PF10351.9 GAN07773.1 - 2.6 6.8 5.0 3.6 6.3 5.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF846 PF05832.12 GAN07774.1 - 1.1e-54 184.3 11.1 1.7e-54 183.7 11.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) UbiA PF01040.18 GAN07774.1 - 0.065 12.5 8.4 0.14 11.5 1.8 2.2 2 0 0 2 2 2 0 UbiA prenyltransferase family DUF2207 PF09972.9 GAN07774.1 - 0.93 8.2 4.7 8.2 5.1 0.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) cobW PF02492.19 GAN07775.1 - 3.3e-33 114.8 0.0 4.1e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 GAN07775.1 - 0.00076 19.6 0.0 0.0069 16.5 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 GAN07775.1 - 0.0054 15.7 0.1 2.5 7.0 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 GAN07775.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 GAN07775.1 - 0.028 14.4 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 GAN07775.1 - 0.044 13.7 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAN07775.1 - 0.06 13.7 0.0 0.073 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 GAN07775.1 - 0.069 13.7 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAN07775.1 - 0.089 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Pox_A32 PF04665.12 GAN07775.1 - 0.092 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Amidohydro_1 PF01979.20 GAN07776.1 - 8.6e-71 239.0 1.8 1.5e-70 238.3 1.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 GAN07776.1 - 2.8e-52 176.1 0.9 5.7e-52 175.2 0.9 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 GAN07776.1 - 1.5e-41 140.7 0.1 5.4e-41 138.9 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 GAN07776.1 - 3.8e-38 129.5 0.0 7.1e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 GAN07776.1 - 4e-06 26.6 0.1 3.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family IBR PF01485.21 GAN07777.1 - 0.0015 18.7 5.0 0.0015 18.7 5.0 4.7 3 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-piccolo PF05715.13 GAN07777.1 - 0.0034 17.5 0.8 0.0034 17.5 0.8 4.3 4 1 0 4 4 4 1 Piccolo Zn-finger Fe_dep_repr_C PF02742.15 GAN07777.1 - 0.11 12.6 0.0 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain TPR_1 PF00515.28 GAN07778.1 - 1.9e-16 59.1 4.7 0.0013 18.5 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAN07778.1 - 1.8e-15 57.2 7.4 3.2e-07 30.8 0.0 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN07778.1 - 4e-14 51.5 9.9 0.037 14.1 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07778.1 - 7.6e-14 51.2 13.6 0.0016 19.1 0.2 7.6 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAN07778.1 - 1.2e-12 48.2 3.6 0.0026 18.4 0.2 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAN07778.1 - 1.2e-11 44.1 2.0 0.8 10.2 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN07778.1 - 3.1e-10 40.1 12.5 0.14 12.4 0.5 6.3 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAN07778.1 - 7.8e-10 38.3 2.9 0.023 14.4 0.0 6.0 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.6 GAN07778.1 - 6.2e-08 32.2 6.7 0.67 10.3 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAN07778.1 - 7.5e-06 26.2 3.3 0.002 18.4 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN07778.1 - 1.3e-05 24.8 13.0 0.63 10.2 0.0 7.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN07778.1 - 0.00023 21.3 3.9 1.1 9.4 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN07778.1 - 0.00023 20.5 12.3 0.0068 15.6 0.0 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 GAN07778.1 - 0.00025 20.8 0.6 0.53 10.0 0.0 3.9 2 2 1 3 3 3 1 Tetratricopeptide repeat-like domain RPN7 PF10602.9 GAN07778.1 - 0.002 17.9 0.1 1.2 8.8 0.0 3.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_4 PF07721.14 GAN07778.1 - 0.0086 16.6 5.7 11 7.0 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAN07778.1 - 0.016 15.0 0.4 14 5.7 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN07778.1 - 0.03 14.6 12.1 0.14 12.4 0.1 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 GAN07778.1 - 0.15 12.4 0.2 49 4.5 0.1 3.4 3 0 0 3 3 2 0 PPR repeat Aldo_ket_red PF00248.21 GAN07779.1 - 1.8e-51 175.1 0.1 5.6e-50 170.2 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family BCS1_N PF08740.11 GAN07780.1 - 8.1e-21 74.8 0.1 2.3e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 GAN07780.1 - 1.5e-20 74.0 0.0 3e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAN07780.1 - 9.8e-06 25.6 0.0 3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAN07780.1 - 9e-05 22.3 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAN07780.1 - 0.00011 22.6 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 GAN07780.1 - 0.0018 17.8 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAN07780.1 - 0.0021 18.5 0.6 0.019 15.4 0.0 2.8 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.12 GAN07780.1 - 0.0043 17.0 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 GAN07780.1 - 0.0052 16.5 0.1 0.033 13.9 0.0 2.3 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 GAN07780.1 - 0.0076 15.6 0.0 0.019 14.4 0.0 1.8 1 1 0 1 1 1 1 KaiC DUF815 PF05673.13 GAN07780.1 - 0.0098 15.1 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAN07780.1 - 0.011 16.3 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAN07780.1 - 0.014 15.2 0.3 0.054 13.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAN07780.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAN07780.1 - 0.022 14.3 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 GAN07780.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_6 PF12774.7 GAN07780.1 - 0.039 12.9 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TIP49 PF06068.13 GAN07780.1 - 0.044 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 GAN07780.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Alg6_Alg8 PF03155.15 GAN07781.1 - 2.2e-144 482.1 27.0 2.8e-144 481.7 27.0 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family p450 PF00067.22 GAN07783.1 - 2.6e-79 267.1 0.0 3.6e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PSDC PF12588.8 GAN07783.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Phophatidylserine decarboxylase FAD_binding_1 PF00667.20 GAN07784.1 - 2.7e-43 148.1 0.0 4e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN07784.1 - 1.4e-26 93.4 0.4 3.4e-26 92.1 0.1 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GAN07784.1 - 1.6e-15 57.7 0.0 4.9e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain adh_short PF00106.25 GAN07784.1 - 0.002 17.6 0.2 0.1 12.0 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase DUF2092 PF09865.9 GAN07785.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) DDOST_48kD PF03345.14 GAN07786.1 - 2.8e-131 438.2 2.9 3.4e-131 437.9 2.9 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta AstA PF04958.12 GAN07786.1 - 0.051 12.1 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit TTD PF12148.8 GAN07786.1 - 0.053 13.4 0.7 0.096 12.5 0.7 1.3 1 0 0 1 1 1 0 Tandem tudor domain within UHRF1 MFS_1 PF07690.16 GAN07787.1 - 7.8e-20 71.1 41.8 7.8e-20 71.1 41.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Thioredoxin PF00085.20 GAN07788.1 - 2.3e-08 33.9 0.1 5.4e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 GAN07788.1 - 2.9e-05 23.2 1.2 3.5e-05 22.9 1.2 1.0 1 0 0 1 1 1 1 Phosducin EamA PF00892.20 GAN07789.1 - 1.1e-17 64.5 36.0 2.8e-07 30.8 15.2 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 GAN07789.1 - 1.7e-05 24.5 10.2 1.7e-05 24.5 10.2 2.4 2 1 1 3 3 3 1 Solute carrier family 35 PUNUT PF16913.5 GAN07789.1 - 9.5e-05 21.8 8.0 0.00058 19.2 3.7 2.3 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport DUF3955 PF13127.6 GAN07789.1 - 0.041 13.7 1.0 0.041 13.7 1.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3955) Nuc_sug_transp PF04142.15 GAN07789.1 - 0.049 12.8 9.7 0.15 11.2 9.7 1.8 1 1 0 1 1 1 0 Nucleotide-sugar transporter Sigma_reg_N PF13800.6 GAN07789.1 - 0.34 11.2 1.9 19 5.6 0.1 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1003 PF06210.11 GAN07789.1 - 0.63 10.2 0.0 0.63 10.2 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1003) Peptidase_S26 PF10502.9 GAN07790.1 - 4.6e-07 29.7 0.0 0.00092 19.0 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAN07790.1 - 1.8e-06 27.8 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like AUDH_Cupin PF18637.1 GAN07791.1 - 0.059 13.4 0.0 4.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain zf-MIZ PF02891.20 GAN07791.1 - 0.096 12.4 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.15 GAN07791.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger FAD_binding_2 PF00890.24 GAN07792.1 - 1.6e-124 416.2 3.8 2.2e-124 415.7 3.8 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAN07792.1 - 2.8e-44 150.2 0.4 4.3e-44 149.6 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 GAN07792.1 - 2.7e-05 23.5 1.7 0.013 14.6 2.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 GAN07792.1 - 3.3e-05 23.2 0.1 0.02 14.2 0.0 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 GAN07792.1 - 0.00015 21.1 1.6 0.001 18.4 0.3 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAN07792.1 - 0.0035 16.7 0.2 0.0056 16.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAN07792.1 - 0.011 14.8 0.3 0.093 11.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 GAN07792.1 - 0.033 13.8 0.9 0.063 12.9 0.9 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAN07792.1 - 0.063 12.0 2.2 0.62 8.7 0.8 2.9 4 0 0 4 4 4 0 HI0933-like protein Amidohydro_3 PF07969.11 GAN07793.1 - 4.5e-22 79.2 1.3 1.4e-10 41.2 0.0 3.5 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 GAN07793.1 - 4.5e-18 65.7 0.3 3.7e-12 46.2 0.0 3.5 3 0 0 3 3 3 3 Amidohydrolase family WRKY PF03106.15 GAN07795.1 - 0.09 13.0 3.8 0.21 11.9 3.8 1.6 1 0 0 1 1 1 0 WRKY DNA -binding domain CytochromB561_N PF09786.9 GAN07795.1 - 0.56 9.1 11.0 0.75 8.7 11.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Miga PF10265.9 GAN07795.1 - 0.82 8.6 7.4 0.97 8.3 7.4 1.1 1 0 0 1 1 1 0 Mitoguardin Cpn60_TCP1 PF00118.24 GAN07797.1 - 4.2e-159 530.3 5.1 4.9e-159 530.1 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 GAN07797.1 - 0.064 12.5 0.4 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Beta_helix_2 PF18835.1 GAN07797.1 - 0.08 12.7 0.0 0.91 9.3 0.0 2.6 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Tom22 PF04281.13 GAN07797.1 - 0.13 12.1 0.1 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Gcd10p PF04189.13 GAN07798.1 - 5.5e-78 262.1 0.9 7.2e-78 261.7 0.9 1.1 1 0 0 1 1 1 1 Gcd10p family RhoGAP PF00620.27 GAN07799.1 - 2.3e-36 124.9 0.0 6.2e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 GAN07799.1 - 4.4e-31 106.9 42.7 8.9e-12 45.1 6.3 5.1 5 0 0 5 5 5 4 LIM domain Aminotran_1_2 PF00155.21 GAN07800.1 - 1.5e-61 208.6 0.0 1.7e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAN07800.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 GAN07800.1 - 0.00023 19.8 0.0 0.00042 19.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAN07800.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAN07800.1 - 0.0053 15.8 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 GAN07800.1 - 0.024 13.3 0.0 0.068 11.8 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-III Polysacc_deac_1 PF01522.21 GAN07801.1 - 5.9e-09 35.9 0.0 1.3e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase C2 PF00168.30 GAN07802.1 - 1.2e-24 86.6 0.1 1.6e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.6 GAN07803.1 - 4e-30 103.4 34.2 4.5e-12 45.5 3.9 4.6 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GAN07803.1 - 2.1e-21 75.7 47.5 4.6e-06 26.9 2.4 7.2 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN07803.1 - 2.2e-12 45.7 32.2 0.53 11.0 0.4 10.6 10 1 0 10 10 10 6 Leucine Rich Repeat LRRNT_2 PF08263.12 GAN07803.1 - 0.012 15.8 3.9 0.034 14.5 3.9 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 GAN07803.1 - 1.3 8.5 11.1 1.1 8.8 1.0 3.4 1 1 2 4 4 4 0 Leucine-rich repeat Ricin_B_lectin PF00652.22 GAN07805.1 - 5.3e-07 29.9 0.1 9.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 GAN07805.1 - 5.3e-05 23.9 0.4 0.0024 18.5 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like UbiA PF01040.18 GAN07806.1 - 1.9e-54 184.7 15.1 2.4e-54 184.3 15.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF155 PF02582.14 GAN07807.1 - 1.6e-26 93.5 0.0 4.4e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 HTH_Tnp_Tc5 PF03221.16 GAN07808.1 - 4.4e-15 55.5 0.0 1.3e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.22 GAN07808.1 - 0.00055 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix CENP-B_N PF04218.13 GAN07808.1 - 0.00065 19.3 0.5 0.00065 19.3 0.5 1.8 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_36 PF13730.6 GAN07808.1 - 0.016 15.1 0.2 0.038 14.0 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain RepA_N PF06970.11 GAN07808.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus HTH_23 PF13384.6 GAN07808.1 - 0.098 12.5 0.2 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain DUF1904 PF08921.11 GAN07808.1 - 0.11 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) JmjC PF02373.22 GAN07809.1 - 4.7e-10 39.9 0.2 5.7e-09 36.4 0.2 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase JHD PF17811.1 GAN07809.1 - 5.2e-07 30.2 0.8 5.2e-07 30.2 0.8 2.6 2 1 1 3 3 3 1 Jumonji helical domain Cupin_8 PF13621.6 GAN07809.1 - 3.3e-06 27.0 0.0 3.3e-06 27.0 0.0 2.9 2 1 0 2 2 2 1 Cupin-like domain PHD PF00628.29 GAN07809.1 - 5.7e-06 26.1 9.3 1.2e-05 25.1 9.3 1.6 1 0 0 1 1 1 1 PHD-finger DNA_pol_phi PF04931.13 GAN07809.1 - 0.038 12.1 25.5 0.065 11.3 25.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4025 PF13217.6 GAN07809.1 - 0.048 13.5 2.4 0.14 12.0 2.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4025) Cupin_1 PF00190.22 GAN07809.1 - 0.13 11.8 0.7 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Cupin XAP5 PF04921.14 GAN07810.1 - 2.7e-86 289.5 12.3 2.7e-86 289.5 12.3 2.0 1 1 0 2 2 2 1 XAP5, circadian clock regulator Pirin_C PF05726.13 GAN07811.1 - 4.6e-32 110.5 0.0 1.8e-30 105.4 0.0 2.4 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Pirin PF02678.16 GAN07811.1 - 4.6e-32 110.2 0.0 7.9e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 GAN07811.1 - 0.031 14.0 2.1 0.045 13.5 0.3 2.2 3 0 0 3 3 3 0 Cupin domain Zn_clus PF00172.18 GAN07812.1 - 3e-09 36.9 8.8 8.1e-09 35.5 8.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LMSTEN PF07988.12 GAN07812.1 - 0.88 9.1 3.3 0.57 9.7 0.6 2.1 2 0 0 2 2 2 0 LMSTEN motif PIF1 PF05970.14 GAN07813.1 - 1.1e-53 182.7 3.2 1e-43 149.9 0.1 3.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GAN07813.1 - 1.4e-24 86.8 0.0 2.6e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN07813.1 - 1.7e-10 41.4 0.0 2.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 GAN07813.1 - 1.7e-07 29.6 0.2 0.00013 20.0 0.0 2.3 2 0 0 2 2 2 2 Helicase T2SSE PF00437.20 GAN07813.1 - 1.3e-05 24.5 0.2 2.4e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.6 GAN07813.1 - 5.1e-05 23.0 0.0 0.00015 21.5 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 GAN07813.1 - 0.00016 21.2 0.4 0.00049 19.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 GAN07813.1 - 0.00024 21.5 0.0 0.00058 20.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAN07813.1 - 0.0012 19.2 0.1 0.0058 16.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain Helicase_RecD PF05127.14 GAN07813.1 - 0.0031 17.4 0.1 0.0086 15.9 0.1 1.8 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 GAN07813.1 - 0.0035 17.7 0.1 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 GAN07813.1 - 0.0076 15.5 0.0 0.019 14.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 GAN07813.1 - 0.0096 16.4 0.4 0.034 14.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 GAN07813.1 - 0.011 15.4 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 GAN07813.1 - 0.018 14.0 0.1 0.034 13.0 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 GAN07813.1 - 0.031 14.2 0.9 0.12 12.3 0.0 2.3 3 0 0 3 3 2 0 NACHT domain PhoH PF02562.16 GAN07813.1 - 0.034 13.6 0.0 0.095 12.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 GAN07813.1 - 0.049 12.8 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.13 GAN07813.1 - 0.061 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 GAN07813.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 GAN07813.1 - 0.075 13.1 0.1 0.67 10.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 GAN07813.1 - 0.09 11.7 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 GAN07813.1 - 0.094 11.8 0.0 0.26 10.4 0.0 1.7 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 GAN07813.1 - 0.1 12.6 0.3 0.64 10.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 GAN07813.1 - 0.1 12.5 0.3 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 GAN07813.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAN07813.1 - 0.11 12.2 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 GAN07813.1 - 0.14 12.0 0.0 0.4 10.5 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RdRP PF05183.12 GAN07814.1 - 5.9e-188 626.2 0.0 7.5e-188 625.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 GAN07814.1 - 0.14 12.0 0.2 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_4 PF07993.12 GAN07815.1 - 2.9e-37 128.2 0.0 1.3e-34 119.5 0.0 2.7 3 0 0 3 3 3 2 Male sterility protein AMP-binding PF00501.28 GAN07815.1 - 1.4e-36 126.1 0.1 5.1e-36 124.2 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAN07815.1 - 7.2e-09 35.9 0.1 1.5e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAN07815.1 - 0.0002 20.9 0.0 0.00086 18.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cellulase PF00150.18 GAN07816.1 - 4.6e-21 75.5 0.0 6.4e-14 52.1 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 GAN07816.1 - 6.3e-18 65.1 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain DSPc PF00782.20 GAN07817.1 - 3.2e-12 46.4 0.0 8.5e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 GAN07817.1 - 0.00026 21.3 0.0 0.00053 20.3 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain CDKN3 PF05706.12 GAN07817.1 - 0.007 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 GAN07817.1 - 0.058 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAN07817.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Chromo PF00385.24 GAN07818.1 - 8.2e-12 44.9 2.3 8.2e-12 44.9 2.3 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 GAN07818.1 - 2.5e-05 24.3 0.3 0.0036 17.4 0.0 2.7 2 0 0 2 2 2 1 Chromo shadow domain FAM163 PF15069.6 GAN07818.1 - 1.2 9.6 3.8 2.8 8.4 3.8 1.5 1 0 0 1 1 1 0 FAM163 family CDC45 PF02724.14 GAN07818.1 - 1.3 7.2 15.8 1.7 6.8 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PRP38_assoc PF12871.7 GAN07818.1 - 3 8.5 23.9 0.3 11.7 18.8 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term CENP-B_dimeris PF09026.10 GAN07818.1 - 4.2 7.8 12.1 11 6.5 12.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RVT PF13966.6 GAN07820.1 - 0.00012 22.7 0.2 0.00022 21.9 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C2H2 PF00096.26 GAN07821.1 - 7.5e-15 54.5 27.9 7.7e-07 29.2 4.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN07821.1 - 7.7e-11 41.9 19.2 1e-07 32.1 1.5 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN07821.1 - 4.2e-10 39.6 23.1 0.0024 18.6 1.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN07821.1 - 1.2e-06 28.4 17.3 0.0081 16.1 1.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN07821.1 - 9.2e-05 22.6 7.8 0.14 12.5 0.7 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 GAN07821.1 - 0.013 15.9 8.2 0.041 14.3 1.7 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 GAN07821.1 - 0.038 13.7 17.6 1.2 9.0 1.6 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 GAN07821.1 - 0.13 12.6 10.2 3.7 8.1 1.6 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Pox_F15 PF04596.12 GAN07821.1 - 0.18 11.5 1.0 0.33 10.7 1.0 1.4 1 0 0 1 1 1 0 Poxvirus protein F15 Zn-ribbon_8 PF09723.10 GAN07821.1 - 0.24 11.5 8.9 1 9.6 2.3 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf_ZIC PF18366.1 GAN07821.1 - 0.4 10.8 4.6 21 5.3 0.1 3.2 2 1 1 3 3 3 0 Zic proteins zinc finger domain DZR PF12773.7 GAN07821.1 - 0.51 10.4 4.6 1.4 9.0 4.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HC_2 PF13913.6 GAN07821.1 - 1.8 8.6 16.0 1 9.4 1.3 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 GAN07821.1 - 2.2 8.6 15.0 0.16 12.3 4.7 3.1 2 1 1 3 3 3 0 C2H2-type zinc ribbon C1_4 PF07975.12 GAN07821.1 - 4.1 7.7 7.6 2.2 8.6 0.9 2.9 1 1 1 2 2 2 0 TFIIH C1-like domain Ogr_Delta PF04606.12 GAN07821.1 - 9.1 6.4 12.9 6.4 6.8 0.2 3.0 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger Glyco_transf_22 PF03901.17 GAN07822.1 - 6.8e-56 190.3 23.8 7.8e-56 190.1 23.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_transf_41 PF13844.6 GAN07823.1 - 2.8e-114 382.1 17.3 1.6e-56 191.7 0.0 4.8 3 1 1 4 4 4 3 Glycosyl transferase family 41 TPR_1 PF00515.28 GAN07823.1 - 3.9e-19 67.6 4.9 0.00014 21.5 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN07823.1 - 3.1e-17 61.3 0.7 2.3e-06 27.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN07823.1 - 8.7e-17 59.8 1.7 0.0036 17.3 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN07823.1 - 1.2e-13 50.5 3.7 0.00064 19.4 0.0 6.2 3 2 3 6 6 6 3 TPR repeat TPR_10 PF13374.6 GAN07823.1 - 2.7e-13 49.3 7.8 0.0064 16.3 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAN07823.1 - 1.2e-12 47.3 5.6 0.019 15.3 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAN07823.1 - 6.1e-10 39.3 5.1 0.11 12.8 0.0 6.0 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAN07823.1 - 3.6e-07 29.7 1.7 0.049 13.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAN07823.1 - 3.6e-07 30.4 0.7 2 9.4 0.0 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN07823.1 - 2.1e-05 25.0 8.1 4.6e-05 24.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAN07823.1 - 0.00053 20.1 0.6 0.0077 16.4 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4666 PF15697.5 GAN07823.1 - 3.7 8.3 11.0 1.3 9.7 2.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4666) Sld5 PF05916.11 GAN07824.1 - 3.8e-09 37.0 0.2 5.6e-09 36.4 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein Tim17 PF02466.19 GAN07825.1 - 2.8e-10 40.5 12.4 4e-10 40.1 12.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SF3b1 PF08920.10 GAN07826.1 - 7.1e-44 149.1 17.6 4.8e-43 146.4 2.5 3.5 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 GAN07826.1 - 1.4e-11 44.6 1.1 0.77 10.3 0.0 7.6 7 1 1 8 8 8 4 HEAT-like repeat HEAT PF02985.22 GAN07826.1 - 2.8e-10 39.6 5.1 1.8 9.1 0.0 8.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 GAN07826.1 - 6e-10 39.4 6.4 0.21 12.0 0.0 7.5 3 2 5 8 8 8 3 HEAT repeats Adaptin_N PF01602.20 GAN07826.1 - 1.1e-05 24.2 3.4 0.026 13.1 0.1 3.2 2 1 0 3 3 3 3 Adaptin N terminal region Dopey_N PF04118.14 GAN07826.1 - 3.1e-05 23.2 0.8 0.16 11.1 0.0 3.7 3 1 1 4 4 4 2 Dopey, N-terminal Vac14_Fab1_bd PF12755.7 GAN07826.1 - 0.00016 22.2 4.1 1.3 9.7 0.0 4.6 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN07826.1 - 0.00049 20.2 8.0 0.79 9.8 0.0 5.9 7 1 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 GAN07826.1 - 0.015 14.4 0.0 8.1 5.4 0.0 3.8 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal TAF6_C PF07571.13 GAN07826.1 - 0.019 15.3 0.0 0.12 12.7 0.0 2.4 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 GAN07826.1 - 0.02 14.5 0.5 21 4.6 0.0 3.5 3 0 0 3 3 3 0 CLASP N terminal NUC173 PF08161.12 GAN07826.1 - 0.023 14.3 1.1 9.7 5.8 0.0 4.4 3 2 2 5 5 5 0 NUC173 domain Arm PF00514.23 GAN07826.1 - 0.035 14.2 0.2 60 3.9 0.0 5.0 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 GAN07826.1 - 0.085 12.4 0.2 6.5 6.2 0.0 3.2 2 1 1 3 3 3 0 Tti2 family DUF1560 PF07597.11 GAN07826.1 - 2.4 8.2 3.8 39 4.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1560) Complex1_49kDa PF00346.19 GAN07827.1 - 3.6e-122 406.7 0.0 5.6e-122 406.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 GAN07827.1 - 0.0012 17.8 0.0 0.0023 16.9 0.0 1.5 1 1 0 1 1 1 1 Nickel-dependent hydrogenase Mito_carr PF00153.27 GAN07828.1 - 1.2e-47 159.8 4.1 1.7e-17 63.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb1_5 PF04998.17 GAN07829.1 - 2.2e-92 309.3 0.1 1.1e-66 225.0 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAN07829.1 - 2.5e-65 219.8 0.1 5.8e-65 218.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAN07829.1 - 3.1e-33 114.9 0.0 8.6e-33 113.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 GAN07829.1 - 8.9e-27 94.2 1.9 1.7e-25 90.0 1.1 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 GAN07829.1 - 1.4e-23 82.9 0.1 6.9e-23 80.6 0.1 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Syntaxin_2 PF14523.6 GAN07829.1 - 0.08 13.3 0.7 2.8 8.4 0.3 3.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF2810 PF10928.8 GAN07829.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) WD40 PF00400.32 GAN07830.1 - 2.9e-45 151.3 14.0 3.8e-09 37.0 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07830.1 - 1.6e-14 53.9 0.6 2e-05 24.8 0.1 5.6 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 GAN07830.1 - 9.4e-13 47.5 3.4 9.4e-13 47.5 3.4 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.8 GAN07830.1 - 5.7e-06 25.3 0.2 0.00069 18.4 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 GAN07830.1 - 0.00049 20.0 0.0 0.069 13.0 0.0 3.1 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN07830.1 - 0.0026 16.8 0.0 2.4 7.0 0.0 3.9 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAN07830.1 - 0.013 14.8 0.1 3.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 GAN07830.1 - 0.015 14.7 0.0 2.4 7.4 0.0 3.5 3 1 1 4 4 4 0 WD40-like domain DUF1340 PF07067.11 GAN07830.1 - 0.17 11.2 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) DUF2540 PF10802.8 GAN07832.1 - 0.059 13.4 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) HLH PF00010.26 GAN07833.1 - 2e-18 66.1 0.2 1.2e-17 63.6 0.0 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain EssA PF10661.9 GAN07833.1 - 2.7 7.8 6.5 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DRMBL PF07522.14 GAN07834.1 - 1.2e-30 105.9 0.0 2.6e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAN07834.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RNF220 PF15926.5 GAN07834.1 - 0.017 14.7 1.5 0.046 13.3 1.5 1.8 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Zn-C2H2_12 PF18112.1 GAN07834.1 - 0.052 14.0 0.1 0.19 12.2 0.1 2.0 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain DUF3637 PF12337.8 GAN07835.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3637) GTP_EFTU PF00009.27 GAN07836.1 - 1.8e-34 119.0 0.0 9.7e-34 116.6 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAN07836.1 - 7.8e-19 67.8 0.0 2.1e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 GAN07836.1 - 1.4e-11 44.6 12.1 1.6e-09 38.0 0.0 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAN07836.1 - 3.8e-09 36.3 0.3 1.3e-08 34.6 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 GAN07836.1 - 1.8e-06 28.0 0.1 1.5e-05 25.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 GAN07836.1 - 0.00034 20.8 0.0 0.00099 19.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAN07836.1 - 0.0093 15.8 0.0 0.048 13.4 0.0 2.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 GAN07836.1 - 0.11 12.8 0.2 3.2 8.0 0.2 3.1 1 1 0 1 1 1 0 AAA domain CS PF04969.16 GAN07837.1 - 1.3e-19 71.0 0.5 2.7e-19 69.9 0.5 1.6 1 0 0 1 1 1 1 CS domain Pkinase PF00069.25 GAN07838.1 - 7.9e-32 110.7 0.0 1.4e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kelch_5 PF13854.6 GAN07838.1 - 6e-20 70.8 5.1 4.9e-07 29.6 1.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAN07838.1 - 3.4e-13 49.4 7.6 3.1e-05 23.9 0.1 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN07838.1 - 8.9e-12 45.0 26.1 1.9e-05 24.8 0.9 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN07838.1 - 2.8e-11 42.9 17.1 0.0011 18.9 0.2 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAN07838.1 - 3.3e-11 43.1 14.9 0.00058 20.1 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAN07838.1 - 6.7e-10 38.4 16.4 0.0042 16.6 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Pkinase_Tyr PF07714.17 GAN07838.1 - 3.6e-07 29.7 0.0 7.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN07838.1 - 4.9e-05 22.8 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Herpes_gE PF02480.16 GAN07838.1 - 0.00015 20.6 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 GAN07838.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.6 2 1 0 2 2 1 0 Transmembrane protein 51 SKG6 PF08693.10 GAN07838.1 - 0.097 12.1 0.3 0.31 10.5 0.3 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 GAN07838.1 - 0.14 13.1 0.0 0.47 11.4 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 GAN07838.1 - 0.15 12.4 0.1 1.9 8.8 0.0 2.8 2 0 0 2 2 2 0 Orf78 (ac78) DUF4718 PF15842.5 GAN07838.1 - 1.7 8.4 0.0 1.7 8.4 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4718) Gram_pos_anchor PF00746.21 GAN07838.1 - 8.3 6.5 7.4 44 4.1 7.4 2.2 1 1 0 1 1 1 0 LPXTG cell wall anchor motif HMG_box PF00505.19 GAN07839.1 - 1.1e-16 61.0 12.7 3e-12 46.8 0.4 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN07839.1 - 2.9e-14 53.4 9.8 1.8e-09 38.0 0.3 3.1 1 1 1 2 2 2 2 HMG-box domain DUF4600 PF15372.6 GAN07839.1 - 0.0016 18.8 1.0 0.0016 18.8 1.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) DDHD PF02862.17 GAN07840.1 - 4.9e-28 98.8 7.3 4.9e-28 98.8 7.3 3.2 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.14 GAN07840.1 - 0.022 14.3 0.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAN07840.1 - 0.041 13.2 0.1 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 GAN07840.1 - 0.042 13.4 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 0 Dienelactone hydrolase family NMT1 PF09084.11 GAN07841.1 - 1.6e-12 47.8 0.0 2.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 GAN07841.1 - 1.3e-08 34.9 0.0 7.4e-07 29.1 0.0 2.8 2 1 0 3 3 3 1 NMT1-like family Phosphonate-bd PF12974.7 GAN07841.1 - 0.0002 21.0 0.0 0.00049 19.8 0.0 1.5 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Phage_terminase PF10668.9 GAN07841.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Phage terminase small subunit Acetyltransf_1 PF00583.25 GAN07842.1 - 5.9e-12 45.9 0.0 8.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN07842.1 - 8.6e-08 32.5 0.2 1.4e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN07842.1 - 1.3e-07 31.6 0.1 1.6e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAN07842.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CadC_C1 PF18500.1 GAN07842.1 - 0.1 12.7 0.3 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 CadC C-terminal domain 1 HNH PF01844.23 GAN07843.1 - 0.00036 20.6 0.2 0.0016 18.5 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.6 GAN07843.1 - 0.0019 18.1 1.3 0.0031 17.4 0.3 1.8 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 GAN07843.1 - 0.0036 17.1 0.0 0.058 13.3 0.0 2.5 2 0 0 2 2 2 1 HNH endonuclease E1_UFD PF09358.10 GAN07843.1 - 0.14 12.9 0.1 0.5 11.1 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin fold domain Glyco_hydro_18 PF00704.28 GAN07844.1 - 2.9e-24 86.4 3.9 6.3e-24 85.3 3.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 GAN07844.1 - 2.8e-16 59.2 21.9 2.8e-16 59.2 21.9 3.1 1 1 1 2 2 2 1 Carbohydrate binding domain (family 19) Sporozoite_P67 PF05642.11 GAN07844.1 - 1.5 6.9 17.2 3 5.8 17.2 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hamartin PF04388.12 GAN07844.1 - 4.4 5.8 6.3 5.9 5.4 6.3 1.1 1 0 0 1 1 1 0 Hamartin protein SR-25 PF10500.9 GAN07844.1 - 6.1 6.4 9.7 11 5.6 9.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Orthopox_A5L PF06193.11 GAN07844.1 - 8.8 5.7 13.5 18 4.6 13.5 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like EPL1 PF10513.9 GAN07845.1 - 5e-21 75.7 1.1 5e-21 75.7 1.1 3.4 2 1 0 3 3 3 2 Enhancer of polycomb-like WD40 PF00400.32 GAN07846.1 - 1.9e-41 139.2 21.4 1e-06 29.3 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 GAN07846.1 - 7.2e-12 45.0 2.0 1.3e-11 44.2 2.0 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 GAN07846.1 - 2.5e-11 43.0 6.8 0.032 12.9 0.0 5.6 2 2 3 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN07846.1 - 1.5e-09 38.0 1.8 1.9 8.8 0.0 5.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAN07846.1 - 2.1e-09 37.0 0.7 5.1e-09 35.8 0.7 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 GAN07846.1 - 7.1e-07 28.8 0.5 2e-06 27.4 0.5 1.9 1 1 0 1 1 1 1 WD40-like domain F-box_4 PF15966.5 GAN07846.1 - 0.00025 20.9 0.5 0.00071 19.4 0.2 1.8 1 1 0 1 1 1 1 F-box PQQ_2 PF13360.6 GAN07846.1 - 0.00026 20.6 0.0 0.042 13.4 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain PALB2_WD40 PF16756.5 GAN07846.1 - 0.0043 16.0 1.2 7.6 5.4 0.0 4.1 1 1 3 4 4 4 1 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 GAN07846.1 - 0.016 15.1 0.1 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN07846.1 - 0.032 13.2 5.2 1.2 8.0 0.1 3.8 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4451 PF14616.6 GAN07847.1 - 8.7e-17 61.5 6.0 8.7e-17 61.5 6.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) Acetyltransf_1 PF00583.25 GAN07848.1 - 1.1e-11 45.0 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN07848.1 - 1.2e-08 35.0 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN07848.1 - 2.6e-08 34.1 0.0 4.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN07848.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAN07848.1 - 0.16 12.1 0.0 0.3 11.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN07849.1 - 0.00037 20.4 0.0 0.00082 19.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN07849.1 - 0.075 13.3 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 GAN07849.1 - 0.13 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein HEAT_2 PF13646.6 GAN07850.1 - 6e-33 113.1 0.1 6e-13 49.0 0.0 3.9 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 GAN07850.1 - 1e-20 72.2 0.0 8.8e-05 22.8 0.1 6.2 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 GAN07850.1 - 5.3e-07 29.4 0.9 1.5 9.3 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 GAN07850.1 - 2.3e-05 24.8 0.2 10 6.7 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 GAN07850.1 - 0.025 14.6 0.6 1.4 9.0 0.1 3.1 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TPP_enzyme_N PF02776.18 GAN07850.1 - 0.11 12.1 0.6 0.51 9.9 0.2 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain RasGEF PF00617.19 GAN07851.1 - 2.3e-55 187.6 2.6 5e-55 186.4 0.2 2.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAN07851.1 - 3.5e-17 62.5 2.4 5.7e-17 61.9 0.2 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 GAN07851.1 - 3.1e-08 33.1 0.2 8.2e-08 31.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 GAN07851.1 - 1.5e-07 31.0 0.1 3.2e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAN07851.1 - 0.00018 21.3 0.5 0.00037 20.3 0.5 1.5 1 0 0 1 1 1 1 Variant SH3 domain Chitin_synth_1 PF01644.17 GAN07852.1 - 1.7e-76 255.7 0.0 2.6e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAN07852.1 - 7.9e-32 109.0 0.1 2.2e-31 107.6 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAN07852.1 - 1.5e-22 80.0 4.0 2.6e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN07852.1 - 0.00032 20.7 15.2 0.0041 17.1 15.2 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAN07852.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Abhydrolase_1 PF00561.20 GAN07853.1 - 4.6e-09 36.3 0.0 1e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN07853.1 - 2.6e-05 23.6 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN07853.1 - 0.0059 17.2 0.0 0.012 16.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAN07854.1 - 3.6e-43 147.5 0.0 6.3e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAN07854.1 - 2.3e-08 33.9 0.0 4.6e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 GAN07854.1 - 0.00028 20.6 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 GAN07854.1 - 0.00055 19.8 0.1 0.0054 16.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN07854.1 - 0.00061 19.1 0.0 0.0043 16.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN07854.1 - 0.0033 17.1 0.2 0.17 11.5 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 GAN07854.1 - 0.011 14.4 0.2 2.6 6.7 0.0 2.5 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 GAN07854.1 - 0.03 14.3 0.0 0.32 10.9 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 GAN07854.1 - 0.058 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF829 PF05705.14 GAN07854.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Nop53 PF07767.11 GAN07856.1 - 6.2e-91 305.7 39.6 6.2e-91 305.7 39.6 1.5 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) T3SchapCesA PF11439.8 GAN07856.1 - 0.045 13.9 6.6 1.8 8.8 0.4 3.0 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA WDCP PF15390.6 GAN07856.1 - 0.28 9.5 9.0 0.4 9.0 9.0 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CBM_21 PF03370.13 GAN07857.1 - 1.5e-22 79.9 4.5 1.5e-22 79.9 4.5 1.8 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAN07857.1 - 2.6e-15 56.8 3.2 5.6e-15 55.7 3.2 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_20 PF00686.19 GAN07857.1 - 0.063 13.2 0.3 0.21 11.5 0.3 1.9 1 0 0 1 1 1 0 Starch binding domain DUF4854 PF16146.5 GAN07857.1 - 0.091 13.1 3.3 0.1 12.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) ENTH PF01417.20 GAN07858.1 - 8.8e-46 155.0 0.0 1.6e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAN07858.1 - 1.2e-05 24.4 2.2 4.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 ANTH domain UIM PF02809.20 GAN07858.1 - 0.00027 20.6 9.4 0.16 12.0 0.5 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif eIF3_subunit PF08597.10 GAN07858.1 - 0.26 11.1 13.2 0.065 13.1 6.8 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF2115 PF09888.9 GAN07858.1 - 0.54 10.8 3.7 1.8 9.0 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) PilX_N PF14341.6 GAN07859.1 - 0.077 13.0 0.8 0.17 11.9 0.8 1.5 1 0 0 1 1 1 0 PilX N-terminal Glyco_hydro_15 PF00723.21 GAN07861.1 - 2.4e-130 435.3 0.0 4.4e-130 434.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 GAN07861.1 - 1.2e-25 89.7 0.2 3.3e-25 88.4 0.2 1.8 1 0 0 1 1 1 1 Interleukin-like EMT inducer SHNi-TPR PF10516.9 GAN07861.1 - 0.0076 15.7 0.2 0.026 14.0 0.2 1.9 1 0 0 1 1 1 1 SHNi-TPR Melibiase_C PF17801.1 GAN07862.1 - 0.16 12.1 0.9 2.4 8.3 0.0 3.0 3 0 0 3 3 3 0 Alpha galactosidase C-terminal beta sandwich domain PTP_N PF12453.8 GAN07862.1 - 1.4 8.7 4.5 0.22 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal DUF3020 PF11223.8 GAN07864.1 - 3.3e-22 78.7 9.4 1.6e-21 76.5 9.4 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3020) RRM_1 PF00076.22 GAN07864.1 - 3.6e-10 39.5 0.1 1.2e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_3 PF07859.13 GAN07865.1 - 1.8e-54 184.8 0.0 2.2e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAN07865.1 - 6.9e-06 25.2 0.0 0.0063 15.4 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family AXE1 PF05448.12 GAN07865.1 - 0.028 13.1 0.0 0.053 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MCM PF00493.23 GAN07866.1 - 2e-99 331.2 0.1 2.8e-99 330.7 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAN07866.1 - 1.3e-37 128.5 0.1 2.5e-37 127.6 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAN07866.1 - 1.8e-29 101.9 1.1 4.8e-29 100.6 1.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 GAN07866.1 - 1e-14 55.1 22.3 1e-14 55.1 22.3 3.7 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 GAN07866.1 - 5.8e-14 52.5 2.8 6.4e-14 52.4 0.5 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAN07866.1 - 1e-08 34.9 0.1 9.9e-07 28.3 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAN07866.1 - 4.3e-05 23.4 0.0 0.00078 19.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAN07866.1 - 4.9e-05 23.3 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 GAN07866.1 - 0.0028 17.4 2.1 0.047 13.5 0.2 2.7 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 GAN07866.1 - 0.034 13.9 0.1 0.33 10.6 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF1642 PF07852.11 GAN07866.1 - 0.09 13.4 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Methyltransf_25 PF13649.6 GAN07867.1 - 4.4e-20 72.2 0.0 6.2e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN07867.1 - 1.5e-19 70.4 0.0 1.5e-18 67.2 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN07867.1 - 5.7e-18 65.5 0.0 1.5e-17 64.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN07867.1 - 6.4e-18 65.1 0.0 1.5e-17 63.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN07867.1 - 2.7e-17 63.0 0.0 4.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN07867.1 - 9.7e-09 35.0 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 GAN07867.1 - 2.7e-07 29.9 0.0 3.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 GAN07867.1 - 3.2e-07 29.7 0.0 7.7e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 GAN07867.1 - 5.2e-07 29.5 0.0 8.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 GAN07867.1 - 6.4e-07 29.2 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 GAN07867.1 - 3.1e-06 26.3 0.0 4.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GAN07867.1 - 4.7e-06 26.7 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAN07867.1 - 6.5e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 GAN07867.1 - 9.8e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 GAN07867.1 - 1.2e-05 24.8 0.0 4.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 GAN07867.1 - 1.3e-05 24.6 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 GAN07867.1 - 9.6e-05 21.9 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 GAN07867.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 GAN07867.1 - 0.008 16.1 0.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.16 GAN07867.1 - 0.019 14.1 0.0 0.026 13.7 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme tRNA_U5-meth_tr PF05958.11 GAN07867.1 - 0.051 12.6 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM13 PF05206.14 GAN07867.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 CheR PF01739.18 GAN07867.1 - 0.14 11.6 0.1 0.49 9.9 0.1 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain zf-C2H2 PF00096.26 GAN07868.1 - 6.7e-16 57.8 17.5 2.3e-05 24.6 2.9 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN07868.1 - 1.8e-12 47.1 6.4 3.8e-07 30.2 0.9 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN07868.1 - 1.1e-06 29.0 27.0 0.00031 21.3 0.3 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN07868.1 - 9.2e-05 22.3 0.2 9.2e-05 22.3 0.2 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN07868.1 - 0.0011 19.2 5.9 0.016 15.5 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding C5HCH PF17982.1 GAN07868.1 - 0.0094 16.1 5.0 0.065 13.4 0.2 3.0 2 0 0 2 2 2 1 NSD Cys-His rich domain zf-met PF12874.7 GAN07868.1 - 0.017 15.5 5.4 0.05 14.0 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 GAN07868.1 - 0.068 13.1 1.7 0.089 12.7 0.5 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.5 GAN07868.1 - 0.077 13.1 1.5 4 7.6 0.1 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-MYST PF17772.1 GAN07868.1 - 1.3 8.7 4.1 9.7 5.9 0.1 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain PDZ_5 PF17817.1 GAN07869.1 - 0.00063 20.0 1.7 0.00063 20.0 1.7 2.1 1 1 1 2 2 2 1 PDZ domain Cas_Cas6 PF01881.16 GAN07869.1 - 0.071 13.7 0.9 0.079 13.5 0.9 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas6 SSP160 PF06933.11 GAN07869.1 - 5.3 5.1 9.3 5.1 5.2 9.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RhoGEF PF00621.20 GAN07870.1 - 1.4e-36 126.4 7.9 1.4e-36 126.4 7.9 2.9 2 1 0 2 2 2 1 RhoGEF domain DUF5327 PF17261.2 GAN07870.1 - 6.6 7.5 21.5 10 7.0 12.1 3.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) UNC-50 PF05216.13 GAN07871.1 - 3.2e-80 268.8 25.2 2e-78 262.9 25.2 2.0 1 1 0 1 1 1 1 UNC-50 family Lipase_3 PF01764.25 GAN07872.1 - 6.1e-24 84.5 0.1 8.8e-18 64.5 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) DUF2974 PF11187.8 GAN07872.1 - 0.1 12.1 0.0 5.5 6.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) TFIIIC_sub6 PF10419.9 GAN07873.1 - 7.7e-09 35.3 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain TAL_FSA PF00923.19 GAN07874.1 - 2.1e-103 345.7 0.4 2.3e-103 345.5 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase 4HBT_3 PF13622.6 GAN07875.1 - 1e-59 202.8 0.0 1.2e-59 202.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 GAN07875.1 - 1.8e-33 115.2 0.0 7.3e-26 90.6 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF1840 PF08895.11 GAN07875.1 - 0.097 13.0 0.2 16 5.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Ras PF00071.22 GAN07876.1 - 1.3e-58 197.2 0.1 1.5e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN07876.1 - 2.2e-20 73.0 0.0 3.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN07876.1 - 3e-07 30.1 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN07876.1 - 0.00012 21.7 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN07876.1 - 0.00035 20.5 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase CTP_transf_3 PF02348.19 GAN07876.1 - 0.00041 20.4 0.4 0.049 13.5 0.1 2.1 1 1 1 2 2 2 2 Cytidylyltransferase IstB_IS21 PF01695.17 GAN07876.1 - 0.005 16.6 0.5 0.052 13.3 0.1 2.3 2 1 1 3 3 3 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 GAN07876.1 - 0.0074 16.4 0.0 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 GAN07876.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF2647 PF10839.8 GAN07876.1 - 1.9 8.6 0.0 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2647) RasGEF PF00617.19 GAN07877.1 - 2.9e-41 141.6 0.0 1e-40 139.8 0.0 2.0 1 1 0 1 1 1 1 RasGEF domain DAZAP2 PF11029.8 GAN07877.1 - 0.029 15.3 0.0 0.029 15.3 0.0 2.7 3 0 0 3 3 3 0 DAZ associated protein 2 (DAZAP2) Pox_RNA_Pol_19 PF05320.12 GAN07877.1 - 1.8 8.5 7.7 1.6 8.7 5.7 2.0 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PBP1_TM PF14812.6 GAN07877.1 - 5.6 7.4 10.6 2.1 8.8 7.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGAP PF00616.19 GAN07878.1 - 2.7e-27 95.8 1.2 6.2e-17 62.0 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 GAN07878.1 - 7.6e-06 26.2 0.0 2.1e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.29 GAN07878.1 - 0.0022 18.5 0.1 0.65 10.5 0.0 3.2 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 GAN07878.1 - 0.041 13.6 4.7 0.64 9.7 0.1 3.6 4 0 0 4 4 4 0 BAR domain of APPL family Myb_DNA-bind_6 PF13921.6 GAN07879.1 - 0.00018 21.7 3.0 0.0005 20.3 3.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN07879.1 - 0.16 12.2 2.1 0.17 12.1 0.5 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain AT_hook PF02178.19 GAN07879.1 - 0.52 10.4 5.2 1.6 8.9 5.2 1.9 1 0 0 1 1 1 0 AT hook motif ANAPC4_WD40 PF12894.7 GAN07880.1 - 4.1e-17 62.3 2.9 0.00023 21.4 0.0 6.9 5 2 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN07880.1 - 4.7e-17 62.0 10.7 0.0082 17.0 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAN07880.1 - 0.00013 21.1 0.0 0.1 11.6 0.0 3.8 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 GAN07880.1 - 0.0046 16.3 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.6 GAN07880.1 - 0.011 15.3 1.4 0.14 11.7 0.6 2.8 2 1 0 2 2 2 0 PQQ-like domain ACBP PF00887.19 GAN07881.1 - 6.7e-23 80.7 0.0 1.8e-22 79.3 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Ank_5 PF13857.6 GAN07881.1 - 3.1e-16 59.2 0.2 6.8e-11 42.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN07881.1 - 3.9e-15 56.0 0.7 6.4e-11 42.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN07881.1 - 3.1e-14 53.3 0.5 1.1e-13 51.5 0.5 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAN07881.1 - 1.1e-13 51.0 1.3 1.5e-07 31.5 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GAN07881.1 - 3.2e-11 42.4 0.1 2.7e-05 24.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Glyco_hydro_3_C PF01915.22 GAN07882.1 - 2.7e-55 187.5 0.1 5.7e-55 186.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAN07882.1 - 2.3e-38 132.4 0.3 5.5e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAN07882.1 - 2.6e-23 81.9 0.0 5.4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.13 GAN07882.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase Diphthami_syn_2 PF01902.17 GAN07883.1 - 9.5e-27 93.9 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Diphthamide synthase Pan3_PK PF18101.1 GAN07884.1 - 1.6e-66 222.5 0.1 2.8e-66 221.7 0.1 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 GAN07884.1 - 0.00033 20.1 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PAM2 PF07145.15 GAN07884.1 - 0.021 14.5 1.5 0.042 13.5 1.5 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Ras PF00071.22 GAN07886.1 - 7.5e-58 194.7 0.4 9.7e-58 194.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN07886.1 - 9.6e-33 112.9 0.1 1.5e-32 112.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN07886.1 - 1.9e-16 60.0 0.1 2.5e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN07886.1 - 3.9e-08 33.4 0.0 6.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN07886.1 - 2.9e-07 30.1 0.1 3.8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAN07886.1 - 7.8e-06 25.6 0.2 2.6e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAN07886.1 - 0.00079 18.9 0.1 0.0042 16.5 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAN07886.1 - 0.0027 17.6 0.2 0.26 11.2 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAN07886.1 - 0.005 16.4 0.0 0.046 13.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 GAN07886.1 - 0.036 13.5 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 GAN07886.1 - 0.056 13.2 0.1 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Complex1_LYR PF05347.15 GAN07887.1 - 9e-08 32.1 3.7 9e-08 32.1 3.7 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAN07887.1 - 0.0051 17.5 2.9 0.015 16.0 1.4 2.2 2 0 0 2 2 2 1 Complex1_LYR-like BRE1 PF08647.11 GAN07888.1 - 0.29 11.2 4.7 0.21 11.7 1.5 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Arm PF00514.23 GAN07889.1 - 5.8e-13 48.4 9.4 1e-05 25.3 0.0 7.2 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAN07889.1 - 0.0016 18.9 1.3 7.9 7.1 0.0 4.4 5 0 0 5 5 5 2 HEAT-like repeat DNA_pol_A PF00476.20 GAN07889.1 - 0.049 12.7 0.0 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase family A Cytidylate_kin PF02224.18 GAN07890.1 - 1.7e-62 210.9 5.9 1.1e-30 106.9 2.0 2.0 2 0 0 2 2 2 2 Cytidylate kinase Cytidylate_kin2 PF13189.6 GAN07890.1 - 2.8e-06 27.6 0.9 2.4e-05 24.6 0.9 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 GAN07890.1 - 0.00084 19.9 0.1 0.0046 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAN07890.1 - 0.00094 19.6 2.1 0.0018 18.7 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 GAN07890.1 - 0.0012 19.0 0.4 0.012 15.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 GAN07890.1 - 0.0017 18.5 1.2 0.024 14.8 0.1 2.4 2 0 0 2 2 2 1 Shikimate kinase ADK PF00406.22 GAN07890.1 - 0.015 15.4 0.1 0.037 14.1 0.1 1.7 1 0 0 1 1 1 0 Adenylate kinase ABC_tran PF00005.27 GAN07890.1 - 0.097 13.2 1.0 0.24 11.9 1.0 1.8 1 1 0 1 1 1 0 ABC transporter dNK PF01712.19 GAN07890.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase Zip PF02535.22 GAN07891.1 - 5e-34 118.0 19.8 3.5e-32 111.9 19.8 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter 7TM-7TMR_HD PF07698.11 GAN07891.1 - 0.0055 16.5 6.5 0.0055 16.5 6.5 2.4 3 0 0 3 3 3 1 7TM receptor with intracellular HD hydrolase DUF308 PF03729.13 GAN07891.1 - 0.033 14.5 0.0 0.033 14.5 0.0 3.6 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) DUF4131 PF13567.6 GAN07891.1 - 0.2 11.3 3.9 1.3 8.7 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) ABC2_membrane_2 PF12679.7 GAN07891.1 - 1.7 7.8 8.9 14 4.8 8.0 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1129 PF06570.11 GAN07891.1 - 5.5 6.4 7.1 1.2 8.6 2.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Dor1 PF04124.12 GAN07893.1 - 7.7e-66 222.1 7.0 1.2e-65 221.4 7.0 1.3 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 GAN07893.1 - 0.011 15.8 0.0 0.042 13.9 0.0 2.0 2 0 0 2 2 2 0 Vps51/Vps67 Spc7_C2 PF15577.6 GAN07893.1 - 0.088 12.9 0.5 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Spc7_C2 Allantoicase PF03561.15 GAN07894.1 - 8.7e-81 269.0 0.0 2.2e-43 147.7 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 GAN07894.1 - 2.8e-52 177.2 0.0 4.1e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase GCP_N_terminal PF17681.1 GAN07895.1 - 1.3e-93 314.0 2.3 4.3e-93 312.3 0.2 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAN07895.1 - 3.4e-87 292.8 9.9 3.4e-87 292.8 9.9 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GLE1 PF07817.13 GAN07896.1 - 7.1e-60 202.3 0.3 7.1e-60 202.3 0.3 3.0 3 0 0 3 3 3 1 GLE1-like protein Hemerythrin PF01814.23 GAN07896.1 - 0.069 13.8 1.9 0.091 13.4 0.0 2.2 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Ndc1_Nup PF09531.10 GAN07896.1 - 0.64 8.6 11.9 0.8 8.3 11.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bindin PF02084.15 GAN07897.1 - 0.1 12.9 0.8 0.6 10.3 0.0 2.4 3 0 0 3 3 3 0 Bindin Thioredoxin PF00085.20 GAN07898.1 - 7.4e-37 125.5 0.4 1.5e-23 82.7 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 GAN07898.1 - 8e-25 87.8 3.0 2.3e-16 60.2 2.5 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAN07898.1 - 7.4e-05 23.0 2.6 1.1 9.7 0.0 4.7 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 GAN07898.1 - 0.00016 22.1 0.1 0.7 10.4 0.2 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GAN07898.1 - 0.0041 16.5 0.1 0.98 8.7 0.0 3.1 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family TSP_C PF05735.12 GAN07898.1 - 0.024 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Thrombospondin C-terminal region Thioredoxin_7 PF13899.6 GAN07898.1 - 0.066 13.4 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 GAN07898.1 - 0.093 12.8 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain 6PGD PF00393.19 GAN07899.1 - 6.8e-130 432.6 0.0 8.3e-130 432.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAN07899.1 - 9.9e-51 172.0 0.0 1.5e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAN07899.1 - 0.016 15.4 0.2 0.48 10.7 0.0 2.8 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAN07899.1 - 0.024 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Band_7 PF01145.25 GAN07900.1 - 7.6e-33 114.0 0.1 1e-32 113.6 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAN07900.1 - 0.00081 19.2 0.1 0.0017 18.1 0.1 1.4 1 1 0 1 1 1 1 SPFH domain-Band 7 family DivIVA PF05103.13 GAN07900.1 - 0.089 12.9 1.0 0.16 12.1 1.0 1.3 1 0 0 1 1 1 0 DivIVA protein Band_7 PF01145.25 GAN07901.1 - 5.6e-30 104.7 0.3 7.6e-30 104.2 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAN07901.1 - 0.072 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family CAP PF00188.26 GAN07902.1 - 2e-22 80.4 11.3 2.3e-21 76.9 11.3 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family GATA PF00320.27 GAN07903.1 - 1.3e-16 59.9 2.7 2.4e-16 59.0 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 GAN07903.1 - 1.4e-14 53.6 1.1 3.4e-14 52.4 1.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Aa_trans PF01490.18 GAN07904.1 - 1.7e-54 185.1 27.5 1.7e-54 185.1 27.5 1.8 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein C1_1 PF00130.22 GAN07905.1 - 3.2e-13 49.4 5.5 5.6e-13 48.6 5.5 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 GAN07905.1 - 0.036 14.0 5.2 0.087 12.7 5.2 1.7 1 0 0 1 1 1 0 PHD-finger Holin_9 PF16936.5 GAN07905.1 - 0.47 10.6 2.4 0.9 9.7 2.4 1.4 1 0 0 1 1 1 0 Putative holin Transketolase_N PF00456.21 GAN07907.1 - 1.9e-158 526.8 0.1 2.5e-158 526.3 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAN07907.1 - 7e-45 152.9 0.0 1.5e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAN07907.1 - 1.4e-10 41.1 0.1 6.6e-10 38.9 0.1 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAN07907.1 - 1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Alba PF01918.21 GAN07907.1 - 0.00095 18.9 1.3 0.0024 17.7 0.1 2.3 2 0 0 2 2 2 1 Alba Terpene_synth PF01397.21 GAN07907.1 - 0.036 13.8 0.2 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Beta_elim_lyase PF01212.21 GAN07907.1 - 0.096 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pkinase PF00069.25 GAN07908.1 - 3.3e-69 233.2 0.0 4.2e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07908.1 - 2.1e-33 115.7 0.0 2.9e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAN07908.1 - 1e-06 29.3 0.5 2.9e-06 27.9 0.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAN07908.1 - 2.9e-06 26.8 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GAN07908.1 - 3.9e-05 23.4 0.0 0.086 12.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAN07908.1 - 0.016 14.1 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_S14 PF00253.21 GAN07908.1 - 0.06 13.1 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DUF3472 PF11958.8 GAN07910.1 - 9.2e-28 97.9 5.7 1.4e-27 97.2 5.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 GAN07910.1 - 1.6e-12 47.8 2.9 2e-12 47.4 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5077) BNR PF02012.20 GAN07910.1 - 0.0071 16.2 2.2 0.017 15.1 1.2 2.3 2 0 0 2 2 2 1 BNR/Asp-box repeat RL11D PF11088.8 GAN07910.1 - 0.087 13.1 0.0 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 Transket_pyr PF02779.24 GAN07911.1 - 4.7e-59 199.0 0.0 7.2e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GAN07911.1 - 1.7e-49 167.5 0.0 2.9e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 GAN07911.1 - 2.3e-45 154.9 0.0 4.4e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF1877 PF08974.10 GAN07911.1 - 0.00083 19.5 0.1 0.0018 18.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) DnaJ-X PF14308.6 GAN07912.1 - 6e-51 172.9 9.4 6e-51 172.9 9.4 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAN07912.1 - 1.3e-25 89.3 3.2 2.3e-25 88.5 1.7 2.3 2 0 0 2 2 2 1 DnaJ domain Mistic PF11458.8 GAN07912.1 - 0.056 13.4 0.4 0.056 13.4 0.4 2.7 3 0 0 3 3 3 0 Membrane-integrating protein Mistic BofC_C PF08955.10 GAN07912.1 - 0.12 12.4 2.1 0.16 12.1 0.1 2.2 2 1 1 3 3 3 0 BofC C-terminal domain AP4E_app_platf PF14807.6 GAN07912.1 - 1.8 9.0 5.7 2.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Spt20 PF12090.8 GAN07912.1 - 2.4 7.7 10.9 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Spt20 family HELP PF03451.14 GAN07913.1 - 2.4 8.1 4.5 22 5.0 0.7 2.3 2 0 0 2 2 2 0 HELP motif Tropomyosin_1 PF12718.7 GAN07914.1 - 1.2e-32 113.0 34.7 1.5e-32 112.7 34.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 GAN07914.1 - 1.1e-07 31.5 32.8 0.00022 20.7 20.6 2.1 1 1 1 2 2 2 2 Tropomyosin FPP PF05911.11 GAN07914.1 - 0.0018 16.5 26.6 0.0025 16.1 26.6 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 GAN07914.1 - 0.0046 17.0 32.1 0.01 15.9 9.4 3.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TRAF_BIRC3_bd PF16673.5 GAN07914.1 - 0.0067 16.2 1.7 0.0067 16.2 1.7 3.2 2 2 1 3 3 3 1 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 GAN07914.1 - 0.007 15.3 27.1 0.0088 15.0 27.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.6 GAN07914.1 - 0.0081 15.5 30.3 0.011 15.1 30.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 GAN07914.1 - 0.014 15.7 31.6 0.07 13.3 25.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 GAN07914.1 - 0.03 12.5 25.8 0.039 12.1 25.8 1.2 1 0 0 1 1 1 0 HOOK protein Lebercilin PF15619.6 GAN07914.1 - 0.098 12.3 33.6 1.8 8.2 32.7 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 GAN07914.1 - 0.19 12.4 24.8 0.34 11.6 3.7 3.3 1 1 1 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 GAN07914.1 - 0.24 11.5 33.1 0.42 10.7 17.7 2.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein BORCS7 PF16088.5 GAN07914.1 - 0.3 11.4 11.0 0.089 13.1 1.5 2.4 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF724 PF05266.14 GAN07914.1 - 0.31 10.8 26.2 0.074 12.9 8.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Lectin_N PF03954.14 GAN07914.1 - 0.46 10.2 16.0 1.1 9.0 2.8 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain FlxA PF14282.6 GAN07914.1 - 0.79 9.7 31.0 0.064 13.3 5.3 3.0 1 1 2 3 3 3 0 FlxA-like protein ADIP PF11559.8 GAN07914.1 - 1.5 8.9 32.0 4.2 7.4 14.3 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 GAN07914.1 - 1.8 9.0 33.8 1.2 9.5 14.5 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 GAN07914.1 - 2 7.7 28.9 2.2 7.5 4.9 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 GAN07914.1 - 2 8.2 31.6 3.3 7.5 7.0 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF812 PF05667.11 GAN07914.1 - 2.1 7.1 30.2 2.6 6.8 30.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_2 PF07716.15 GAN07914.1 - 3.5 7.8 27.6 4.4 7.5 3.3 4.2 2 2 2 4 4 4 0 Basic region leucine zipper DUF4407 PF14362.6 GAN07914.1 - 3.6 6.9 24.9 46 3.2 24.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMCO5 PF14992.6 GAN07914.1 - 3.9 7.0 30.6 0.35 10.4 17.6 2.1 1 1 2 3 3 3 0 TMCO5 family DHR10 PF18595.1 GAN07914.1 - 4 7.5 37.1 15 5.6 22.4 2.9 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 GAN07914.1 - 4.2 7.6 31.9 0.39 10.9 22.7 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 GAN07914.1 - 4.6 6.2 28.0 1.4 8.0 14.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 GAN07914.1 - 4.7 7.3 19.2 4.5 7.3 7.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) KxDL PF10241.9 GAN07914.1 - 5.6 7.3 25.3 1.9 8.8 2.5 3.8 1 1 2 4 4 4 0 Uncharacterized conserved protein CASP_C PF08172.12 GAN07914.1 - 6.5 6.0 20.2 2.2 7.5 9.7 2.1 2 0 0 2 2 2 0 CASP C terminal TMPIT PF07851.13 GAN07914.1 - 6.8 5.8 22.7 1.2 8.3 9.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein KLRAQ PF10205.9 GAN07914.1 - 7 7.0 25.3 5.3 7.3 8.9 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Fez1 PF06818.15 GAN07914.1 - 7.6 6.9 25.6 40 4.6 25.6 2.0 1 1 0 1 1 1 0 Fez1 Mito_fiss_reg PF05308.11 GAN07914.1 - 9 6.3 15.7 0.24 11.5 7.3 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator DUF1746 PF08508.10 GAN07915.1 - 2.4e-07 31.1 0.2 5e-07 30.1 0.1 1.5 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1746) ABC_membrane PF00664.23 GAN07916.1 - 3.9e-112 374.4 34.1 1e-61 209.1 14.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN07916.1 - 1.2e-69 233.1 0.3 1.1e-34 119.9 0.2 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN07916.1 - 2.6e-15 56.5 0.0 1.1e-05 25.0 1.3 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAN07916.1 - 2.7e-08 34.4 1.7 0.0054 17.1 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAN07916.1 - 2.9e-08 33.3 0.4 0.0075 16.0 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 GAN07916.1 - 4.6e-08 32.3 0.7 0.0018 17.2 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 GAN07916.1 - 4.9e-08 33.3 1.0 0.0057 16.9 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 GAN07916.1 - 7.4e-08 32.9 0.2 0.31 11.4 0.0 4.1 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GAN07916.1 - 1.9e-06 27.9 0.0 0.012 15.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 GAN07916.1 - 2.4e-06 27.0 0.1 0.011 15.0 0.1 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 GAN07916.1 - 5.3e-06 26.3 0.1 0.086 12.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAN07916.1 - 1.8e-05 24.7 0.1 0.078 12.8 0.1 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 GAN07916.1 - 2e-05 24.0 0.3 0.066 12.5 0.0 3.4 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 GAN07916.1 - 3.2e-05 23.8 0.0 0.0021 17.8 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 GAN07916.1 - 7.7e-05 22.3 0.0 0.43 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 GAN07916.1 - 0.00059 19.1 0.0 0.26 10.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 GAN07916.1 - 0.00059 19.8 0.2 4.9 7.2 0.0 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAN07916.1 - 0.0024 17.1 0.1 0.36 10.0 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 GAN07916.1 - 0.003 17.3 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 GAN07916.1 - 0.0043 17.3 5.0 1.6 9.0 0.4 4.0 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 GAN07916.1 - 0.0044 17.0 0.2 0.24 11.3 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain RNA_helicase PF00910.22 GAN07916.1 - 0.0049 17.2 0.0 7.4 7.0 0.0 3.6 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 GAN07916.1 - 0.0057 16.7 0.8 5.1 7.2 0.1 3.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 GAN07916.1 - 0.0069 16.1 0.7 5 6.8 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_18 PF13238.6 GAN07916.1 - 0.0072 16.9 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAN07916.1 - 0.0074 16.5 0.0 6.8 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAN07916.1 - 0.0092 16.2 0.5 8.3 6.6 0.0 3.5 3 1 0 3 3 3 0 AAA domain PRK PF00485.18 GAN07916.1 - 0.013 15.2 0.1 1.9 8.2 0.1 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 GAN07916.1 - 0.018 15.4 0.3 22 5.4 0.0 3.8 4 1 1 5 5 4 0 AAA domain Mg_chelatase PF01078.21 GAN07916.1 - 0.019 14.4 0.0 3.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 GAN07916.1 - 0.029 13.7 0.0 2.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Septin DUF87 PF01935.17 GAN07916.1 - 0.051 13.7 0.3 4.7 7.2 0.1 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 GAN07916.1 - 0.055 13.0 0.3 11 5.5 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 GAN07916.1 - 0.071 13.6 7.1 0.41 11.1 0.1 3.3 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 GAN07916.1 - 0.1 12.5 0.6 7.5 6.4 0.0 3.0 3 0 0 3 3 2 0 NACHT domain APS_kinase PF01583.20 GAN07916.1 - 0.1 12.5 0.1 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase TniB PF05621.11 GAN07916.1 - 0.11 12.0 0.0 46 3.3 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein TMEM135_C_rich PF15982.5 GAN07917.1 - 1.4e-06 29.0 0.3 3.5e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 GAN07917.1 - 0.0017 18.7 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family DUF1449 PF07290.11 GAN07917.1 - 0.018 14.6 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Patatin PF01734.22 GAN07917.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase PgpA PF04608.13 GAN07917.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A AT_hook PF02178.19 GAN07918.1 - 2.1e-07 30.0 21.8 0.011 15.5 3.0 4.0 3 0 0 3 3 3 3 AT hook motif WD40 PF00400.32 GAN07919.1 - 3.9e-22 78.1 8.2 0.00011 22.9 0.4 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07919.1 - 1.9e-06 28.1 0.6 0.48 10.8 0.0 4.8 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DDHD PF02862.17 GAN07919.1 - 0.0062 16.7 11.4 0.0062 16.7 11.4 1.8 2 0 0 2 2 2 1 DDHD domain Spc7_N PF15402.6 GAN07919.1 - 0.14 10.3 17.3 0.26 9.5 17.3 1.4 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 NARP1 PF12569.8 GAN07919.1 - 0.32 9.8 15.7 0.47 9.3 15.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4746 PF15928.5 GAN07919.1 - 0.33 10.3 8.0 0.47 9.8 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LAM_C PF12544.8 GAN07919.1 - 0.59 10.3 3.8 1.3 9.2 3.8 1.5 1 0 0 1 1 1 0 Lysine-2,3-aminomutase CPSF100_C PF13299.6 GAN07919.1 - 0.59 10.3 14.2 1 9.6 14.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.12 GAN07919.1 - 0.62 9.0 24.0 0.062 12.3 19.7 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GREB1 PF15782.5 GAN07919.1 - 0.67 7.0 24.5 0.89 6.6 24.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 GAN07919.1 - 1.1 8.7 31.4 0.32 10.5 27.7 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FAM76 PF16046.5 GAN07919.1 - 1.1 8.5 22.5 13 5.1 0.0 2.2 2 0 0 2 2 2 0 FAM76 protein ALMT PF11744.8 GAN07919.1 - 1.2 7.9 17.9 1.7 7.4 17.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter VIT1 PF01988.19 GAN07919.1 - 1.8 8.4 5.1 1.4 8.7 3.6 1.7 2 0 0 2 2 2 0 VIT family Presenilin PF01080.17 GAN07919.1 - 1.9 7.2 25.7 2.8 6.6 25.7 1.2 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 GAN07919.1 - 2 7.2 16.4 3.3 6.5 16.4 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EPL1 PF10513.9 GAN07919.1 - 2.2 8.6 20.5 6.5 7.1 20.5 1.8 1 0 0 1 1 1 0 Enhancer of polycomb-like SLC12 PF03522.15 GAN07919.1 - 2.9 6.8 23.6 4.8 6.1 23.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4638 PF15472.6 GAN07919.1 - 3.9 7.1 13.7 8.1 6.1 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Otopetrin PF03189.13 GAN07919.1 - 4.2 6.1 8.9 5.9 5.6 8.9 1.2 1 0 0 1 1 1 0 Otopetrin CDC45 PF02724.14 GAN07919.1 - 4.5 5.4 18.0 6.8 4.9 18.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TCP PF03634.13 GAN07919.1 - 5.2 7.6 20.5 14 6.2 20.5 1.8 1 0 0 1 1 1 0 TCP family transcription factor Gti1_Pac2 PF09729.9 GAN07919.1 - 6.3 6.9 17.1 14 5.7 17.1 1.7 1 0 0 1 1 1 0 Gti1/Pac2 family Plasmodium_Vir PF05795.11 GAN07919.1 - 7.5 5.9 10.2 11 5.3 10.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.12 GAN07919.1 - 8.4 6.1 22.1 13 5.5 22.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2358 PF10184.9 GAN07920.1 - 1.1e-12 48.2 0.2 1.3e-07 31.8 0.1 3.1 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2358) MMU163 PF17119.5 GAN07920.1 - 1.1e-07 31.3 0.1 0.0012 18.1 0.0 2.5 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis DEAD PF00270.29 GAN07921.1 - 7.1e-44 149.7 0.0 1.4e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN07921.1 - 1.4e-21 76.9 0.0 8.1e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAN07921.1 - 8.3e-18 64.4 0.3 1.7e-17 63.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAN07921.1 - 1.7e-06 28.1 7.2 1.3e-05 25.3 0.0 3.9 4 1 1 5 5 5 1 Type III restriction enzyme, res subunit FWWh PF14922.6 GAN07921.1 - 0.0044 17.0 0.1 0.0096 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function Cwf_Cwc_15 PF04889.12 GAN07921.1 - 0.0055 16.5 1.2 0.0055 16.5 1.2 1.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein AAA_22 PF13401.6 GAN07921.1 - 0.016 15.5 0.2 0.11 12.7 0.2 2.3 1 1 0 1 1 1 0 AAA domain FIST PF08495.10 GAN07922.1 - 1.2e-06 28.7 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 FIST N domain FIST_C PF10442.9 GAN07922.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 FIST C domain AA_kinase PF00696.28 GAN07923.1 - 1.5e-41 142.5 0.0 2.3e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 GAN07923.1 - 4.7e-13 48.7 0.3 3.2e-06 26.8 0.1 3.5 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 GAN07923.1 - 4.5e-11 42.4 3.3 5.8e-08 32.4 1.1 2.7 2 0 0 2 2 2 2 ACT domain DUF334 PF03904.13 GAN07923.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF334) Fungal_trans PF04082.18 GAN07925.1 - 7.8e-32 110.4 1.5 2.4e-31 108.8 1.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN07925.1 - 5.5e-07 29.6 13.4 1.2e-06 28.5 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MitMem_reg PF13012.6 GAN07926.1 - 6.7e-33 113.5 0.1 1.3e-32 112.6 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAN07926.1 - 2.7e-15 56.4 0.0 4.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Aa_trans PF01490.18 GAN07927.1 - 3.6e-31 108.3 11.9 5.5e-31 107.7 11.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 GAN07928.1 - 4.5e-18 65.2 7.6 5.3e-18 64.9 7.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAN07928.1 - 7.4e-06 25.3 3.5 8.7e-06 25.0 3.5 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family HlyE PF06109.13 GAN07928.1 - 0.45 9.8 2.3 0.59 9.4 2.3 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) Proteasome PF00227.26 GAN07929.1 - 1.9e-50 171.0 0.5 2.1e-50 170.9 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit ABC_membrane PF00664.23 GAN07930.1 - 8.8e-119 396.2 24.0 7.7e-61 206.1 10.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN07930.1 - 2.5e-64 215.9 0.1 5.5e-32 111.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN07930.1 - 2e-15 56.9 0.0 1.6e-07 31.0 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN07930.1 - 3e-08 34.0 1.1 0.0027 18.0 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAN07930.1 - 3.2e-08 34.1 0.3 0.014 15.8 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 GAN07930.1 - 8.6e-08 31.4 1.5 0.00073 18.4 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAN07930.1 - 1.2e-07 31.8 0.1 0.0086 16.0 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 GAN07930.1 - 4.4e-07 29.8 1.2 0.054 13.2 0.3 3.4 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 GAN07930.1 - 1.2e-06 27.9 0.1 0.028 13.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 GAN07930.1 - 1.3e-05 24.8 2.0 0.039 13.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAN07930.1 - 2.2e-05 24.9 1.4 0.63 10.5 0.3 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAN07930.1 - 5.6e-05 23.5 1.8 1.9 8.7 0.3 3.6 2 1 1 3 3 3 1 AAA domain G-alpha PF00503.20 GAN07930.1 - 0.00019 20.7 0.0 0.6 9.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 GAN07930.1 - 0.00021 21.5 4.0 0.62 10.3 0.4 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 GAN07930.1 - 0.00042 19.9 0.1 0.75 9.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 GAN07930.1 - 0.00045 20.2 0.0 2.3 8.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAN07930.1 - 0.0005 19.3 0.0 0.093 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 GAN07930.1 - 0.00053 19.8 0.0 0.092 12.4 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain SRP54 PF00448.22 GAN07930.1 - 0.00056 19.6 0.2 0.57 9.8 0.1 2.8 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 GAN07930.1 - 0.00088 19.0 0.0 0.94 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAN07930.1 - 0.001 19.2 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAN07930.1 - 0.0012 18.4 0.7 5.1 6.6 0.1 4.1 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 GAN07930.1 - 0.0014 18.5 0.0 0.077 12.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 GAN07930.1 - 0.0015 19.1 0.0 1.6 9.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAN07930.1 - 0.0042 16.9 0.1 12 5.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 GAN07930.1 - 0.0073 16.7 0.0 5.2 7.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase MMR_HSR1 PF01926.23 GAN07930.1 - 0.01 15.9 0.2 7.4 6.7 0.1 3.4 3 1 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAN07930.1 - 0.038 13.8 0.1 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 GAN07930.1 - 0.053 13.4 0.1 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 GAN07930.1 - 0.058 13.1 0.0 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family GMC_oxred_N PF00732.19 GAN07930.1 - 0.07 12.5 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase DUF87 PF01935.17 GAN07930.1 - 0.084 13.0 1.1 9.7 6.2 0.0 2.9 2 0 0 2 2 2 0 Helicase HerA, central domain DUF4710 PF15828.5 GAN07930.1 - 2.6 8.2 6.4 6.8 6.9 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) Sec5 PF15469.6 GAN07931.1 - 3.2e-52 177.1 3.6 3.2e-52 177.1 3.6 3.3 4 0 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.11 GAN07931.1 - 1e-05 25.5 1.0 1e-05 25.5 1.0 3.4 3 0 0 3 3 3 1 Vps51/Vps67 Lipase_GDSL_2 PF13472.6 GAN07934.1 - 1.3e-06 28.9 0.1 2.1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAN07934.1 - 3.9e-06 27.0 0.2 5.4e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3798 PF12683.7 GAN07934.1 - 0.072 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) TLD PF07534.16 GAN07935.1 - 3.6e-29 101.8 1.2 7.3e-29 100.8 1.2 1.6 1 0 0 1 1 1 1 TLD Wax2_C PF12076.8 GAN07935.1 - 0.29 10.8 1.4 28 4.4 0.0 2.9 3 0 0 3 3 3 0 WAX2 C-terminal domain Kelch_1 PF01344.25 GAN07936.1 - 1.7e-40 136.4 2.6 1.8e-06 27.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAN07936.1 - 1.9e-37 127.1 5.0 3.7e-08 33.2 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN07936.1 - 1.4e-36 123.9 4.3 6.7e-07 29.2 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAN07936.1 - 5.8e-36 122.1 6.5 1.4e-05 25.3 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN07936.1 - 6.5e-34 115.1 7.3 1.2e-05 25.4 0.1 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAN07936.1 - 5e-33 111.8 6.7 1.9e-05 24.4 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Rot1 PF10681.9 GAN07937.1 - 0.064 12.8 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal RT_RNaseH_2 PF17919.1 GAN07938.1 - 1.1e-35 121.7 0.0 2.1e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAN07938.1 - 1.2e-34 118.7 0.0 2.3e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAN07938.1 - 3e-22 79.3 0.1 4.9e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GAN07938.1 - 7.7e-09 36.0 0.0 1.6e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAN07938.1 - 2.2e-07 31.4 0.0 4.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 GAN07938.1 - 7e-06 26.2 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 GAN07938.1 - 0.00014 21.8 3.0 0.00033 20.6 3.0 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 GAN07938.1 - 0.00019 21.2 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 GAN07938.1 - 0.0031 17.3 2.0 0.0066 16.2 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GAN07938.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Methyltransf_23 PF13489.6 GAN07938.1 - 0.16 11.8 0.0 0.5 10.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain zf-CCHC_6 PF15288.6 GAN07938.1 - 0.26 11.1 1.9 0.65 9.9 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle A_deaminase PF00962.22 GAN07939.1 - 2e-125 418.5 0.0 2.6e-125 418.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase NAD_binding_10 PF13460.6 GAN07940.1 - 1.6e-15 57.4 0.0 2.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN07940.1 - 3e-13 49.9 0.0 4.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAN07940.1 - 1.5e-12 47.5 0.1 5e-12 45.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN07940.1 - 3.9e-12 45.8 0.1 7.1e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAN07940.1 - 2e-08 33.7 0.0 0.0043 16.2 0.0 2.4 2 0 0 2 2 2 2 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 GAN07940.1 - 6.8e-07 29.6 0.1 2.6e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAN07940.1 - 2.3e-05 24.0 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 GAN07940.1 - 2.3e-05 24.0 0.1 9.5e-05 21.9 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAN07940.1 - 2.8e-05 23.4 0.1 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 GAN07940.1 - 0.0018 17.8 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 GAN07940.1 - 0.056 13.6 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 GAN07940.1 - 0.065 13.1 0.1 0.46 10.4 0.0 2.3 3 0 0 3 3 3 0 KR domain Microtub_bind PF13931.6 GAN07941.1 - 0.054 13.9 12.5 0.21 11.9 12.6 1.8 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding SERTA PF06031.13 GAN07941.1 - 0.085 12.5 0.1 0.085 12.5 0.1 1.6 2 0 0 2 2 2 0 SERTA motif Astro_capsid_p PF12226.8 GAN07941.1 - 0.45 9.6 12.0 0.64 9.1 12.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 GAN07941.1 - 2.1 7.6 10.7 2.5 7.4 10.7 1.0 1 0 0 1 1 1 0 BUD22 zf-A20 PF01754.16 GAN07942.1 - 4e-09 36.2 9.9 9.7e-09 35.0 9.9 1.7 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 GAN07942.1 - 1.3e-07 31.7 11.3 1.3e-07 31.7 11.3 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Cyclin PF08613.11 GAN07943.1 - 3.5e-14 53.5 0.2 3.5e-14 53.5 0.2 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAN07943.1 - 3.5e-06 26.8 6.2 4.9e-06 26.3 0.3 2.8 2 1 0 3 3 3 1 Cyclin, N-terminal domain Hormone_4 PF00220.17 GAN07944.1 - 0.22 11.5 0.6 0.69 10.0 0.6 1.9 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain ORMDL PF04061.14 GAN07945.1 - 2.4e-55 186.1 6.7 2.8e-55 185.8 6.7 1.1 1 0 0 1 1 1 1 ORMDL family DUF2238 PF09997.9 GAN07945.1 - 0.042 13.6 1.1 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) Syntaxin PF00804.25 GAN07946.1 - 1.7e-24 86.6 15.4 9.1e-19 67.9 1.3 2.5 3 0 0 3 3 3 2 Syntaxin SNARE PF05739.19 GAN07946.1 - 4.3e-05 23.4 6.4 5.8e-05 23.0 0.7 2.4 2 0 0 2 2 2 1 SNARE domain YajC PF02699.15 GAN07946.1 - 0.0031 17.3 0.3 0.0084 16.0 0.3 1.7 1 0 0 1 1 1 1 Preprotein translocase subunit DUF4094 PF13334.6 GAN07946.1 - 0.026 14.9 0.6 0.026 14.9 0.6 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) DUF4988 PF16378.5 GAN07946.1 - 0.12 12.0 5.5 0.43 10.2 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF1759 PF03564.15 GAN07946.1 - 0.19 11.7 6.0 0.16 11.9 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) Allexi_40kDa PF05549.11 GAN07946.1 - 1.4 8.4 12.5 0.14 11.6 3.6 2.4 2 1 0 2 2 2 0 Allexivirus 40kDa protein DUF1644 PF07800.12 GAN07946.1 - 2 8.5 6.0 0.54 10.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) ACCA PF03255.14 GAN07946.1 - 3.5 7.5 8.8 0.51 10.2 0.3 2.8 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ras PF00071.22 GAN07947.1 - 2e-42 144.5 0.0 4.4e-42 143.4 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN07947.1 - 1.1e-26 93.4 0.2 7.2e-26 90.8 0.1 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FAM178 PF14816.6 GAN07947.1 - 2.2e-12 46.7 0.8 7.9e-12 44.8 0.8 1.9 1 1 0 1 1 1 1 Family of unknown function, FAM178 Arf PF00025.21 GAN07947.1 - 1.9e-08 34.0 0.0 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN07947.1 - 0.00055 19.4 0.0 0.0016 17.8 0.0 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TsaE PF02367.17 GAN07947.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAN07947.1 - 0.0078 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 GAN07947.1 - 0.045 13.7 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 GAN07947.1 - 0.049 13.7 0.2 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAN07947.1 - 0.069 13.4 0.1 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain BCS1_N PF08740.11 GAN07948.1 - 3.4e-52 177.2 0.4 4.8e-52 176.7 0.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAN07948.1 - 1.1e-20 74.3 0.0 2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GAN07948.1 - 0.00022 20.5 0.0 0.00079 18.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAN07948.1 - 0.00087 19.7 0.0 0.0027 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 GAN07948.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAN07948.1 - 0.0041 16.8 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 GAN07948.1 - 0.0057 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAN07948.1 - 0.0087 16.4 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 GAN07948.1 - 0.0089 16.0 0.0 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAN07948.1 - 0.012 15.3 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAN07948.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAN07948.1 - 0.018 15.6 0.0 0.035 14.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 GAN07948.1 - 0.021 15.1 0.0 0.073 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAN07948.1 - 0.024 14.1 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 GAN07948.1 - 0.047 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 GAN07948.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 GAN07948.1 - 0.14 12.1 0.0 1 9.2 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 GAN07948.1 - 0.14 11.7 0.0 0.69 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAN07948.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC SPRY PF00622.28 GAN07949.1 - 2.1e-19 69.8 0.4 3.3e-19 69.2 0.4 1.3 1 0 0 1 1 1 1 SPRY domain GIDA PF01134.22 GAN07950.1 - 5.6e-149 496.5 0.0 8.4e-149 495.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GAN07950.1 - 2.3e-71 240.3 0.1 3.7e-71 239.7 0.1 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 GAN07950.1 - 1.6e-06 27.7 1.6 3.3e-06 26.7 1.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN07950.1 - 2e-06 27.3 2.6 6.8e-05 22.2 1.9 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAN07950.1 - 0.00012 21.3 1.1 0.00012 21.3 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAN07950.1 - 0.00012 21.4 0.0 0.00028 20.2 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAN07950.1 - 0.00013 20.8 5.7 0.008 14.9 0.4 2.8 3 0 0 3 3 3 2 HI0933-like protein DUF3659 PF12396.8 GAN07950.1 - 0.15 12.0 0.0 0.47 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) NAD_binding_8 PF13450.6 GAN07950.1 - 0.18 12.0 0.6 0.59 10.4 0.6 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ATP-synt_S1 PF05827.12 GAN07952.1 - 9.5e-05 22.3 0.1 0.0002 21.2 0.1 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Sulfatase PF00884.23 GAN07952.1 - 0.0045 16.4 0.2 2 7.7 0.1 2.4 2 1 0 2 2 2 2 Sulfatase Lipase_GDSL_2 PF13472.6 GAN07953.1 - 1.6e-06 28.6 0.0 1.1e-05 26.0 0.0 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAN07953.1 - 0.0054 16.7 0.1 0.032 14.2 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SASA PF03629.18 GAN07953.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase Wza_C PF18412.1 GAN07954.1 - 0.016 15.0 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain UBA2_C PF16195.5 GAN07954.1 - 0.97 10.2 7.9 3.4 8.4 0.1 2.7 2 1 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus PH PF00169.29 GAN07955.1 - 4.7e-16 59.2 0.1 8.6e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAN07955.1 - 0.0018 18.7 0.5 0.016 15.6 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAN07955.1 - 0.029 14.7 0.0 0.095 13.1 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 GAN07955.1 - 0.071 13.4 0.5 1.2 9.5 0.5 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PAC4 PF16093.5 GAN07955.1 - 0.13 12.4 1.0 0.33 11.2 0.2 2.0 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 TFIIB PF00382.19 GAN07956.1 - 2e-45 152.7 1.8 2.3e-24 85.2 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GAN07956.1 - 1.8e-14 52.9 1.1 3e-14 52.2 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 GAN07956.1 - 0.00041 20.4 0.2 0.076 13.1 0.1 2.4 2 1 0 2 2 2 2 Cyclin, C-terminal domain RB_B PF01857.20 GAN07956.1 - 0.00045 20.2 1.4 0.00076 19.5 1.3 1.5 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 GAN07956.1 - 0.041 13.6 1.8 0.25 11.1 0.6 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain GDP_Man_Dehyd PF16363.5 GAN07957.1 - 1.7e-162 540.5 0.0 1.9e-162 540.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAN07957.1 - 1.4e-75 253.9 0.0 1.8e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAN07957.1 - 5.4e-08 32.3 0.0 7.9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAN07957.1 - 4.3e-05 22.8 0.0 6.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GAN07957.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family PNP_UDP_1 PF01048.20 GAN07958.1 - 4.7e-24 84.9 0.0 6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2034 PF10356.9 GAN07959.1 - 1.2e-20 73.7 4.3 7.2e-10 38.6 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 GAN07959.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease Mrr_cat_2 PF13156.6 GAN07959.1 - 0.085 12.8 0.7 0.2 11.6 0.2 2.0 1 1 1 2 2 2 0 Restriction endonuclease DUF3808 PF10300.9 GAN07960.1 - 3e-73 247.2 13.3 5.4e-30 104.6 0.1 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF3808) TPR_8 PF13181.6 GAN07960.1 - 0.27 11.5 2.3 2.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 GAN07960.1 - 0.77 9.9 19.3 4.2 7.5 5.7 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3456 PF11938.8 GAN07960.1 - 0.88 10.1 5.3 0.82 10.2 1.1 2.3 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP TERB2 PF15101.6 GAN07960.1 - 1.1 9.3 11.7 0.12 12.4 2.5 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Na_trans_assoc PF06512.13 GAN07960.1 - 5.7 7.2 10.1 0.84 9.9 3.9 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated Sel1 PF08238.12 GAN07961.1 - 4.4e-16 59.0 9.3 0.00033 21.2 1.0 4.4 4 0 0 4 4 4 3 Sel1 repeat TPR_3 PF07720.12 GAN07961.1 - 0.075 13.0 4.8 0.87 9.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN07961.1 - 0.78 9.7 3.6 2.4 8.1 0.2 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat G-alpha PF00503.20 GAN07962.1 - 2.7e-102 342.6 3.4 3.2e-102 342.3 3.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN07962.1 - 6.6e-13 48.5 1.1 5.9e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAN07962.1 - 0.0034 17.6 0.1 1.8 8.8 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAN07962.1 - 0.004 16.5 1.1 0.51 9.6 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAN07962.1 - 0.033 13.7 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 GAN07962.1 - 0.078 12.7 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thiolase_N PF00108.23 GAN07964.1 - 3.3e-18 66.0 0.2 6e-17 61.9 0.2 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN07964.1 - 1.7e-12 47.1 0.1 7.4e-12 45.0 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 GAN07964.1 - 0.0002 21.3 0.1 0.16 12.0 0.0 3.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 GAN07964.1 - 0.00031 20.4 6.3 0.029 13.9 1.1 2.6 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAN07964.1 - 0.00084 19.1 0.2 0.026 14.4 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.17 GAN07964.1 - 0.019 14.8 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal SpoVAD PF07451.11 GAN07964.1 - 0.031 13.0 0.6 0.98 8.1 0.1 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) CDC37_N PF03234.14 GAN07965.1 - 0.55 11.1 9.5 0.061 14.2 3.4 2.4 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding BCL_N PF04714.13 GAN07966.1 - 0.0022 18.0 1.1 0.0046 17.0 1.1 1.6 1 0 0 1 1 1 1 BCL7, N-terminal conserver region zf_Hakai PF18408.1 GAN07966.1 - 0.12 12.1 4.4 0.28 10.9 4.4 1.6 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain FSA_C PF10479.9 GAN07966.1 - 1.4 7.0 16.3 2 6.4 16.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Med2 PF11214.8 GAN07967.1 - 0.013 15.7 0.2 0.043 14.0 0.1 1.9 1 1 1 2 2 2 0 Mediator complex subunit 2 Methyltransf_PK PF05891.12 GAN07967.1 - 0.068 12.7 0.1 0.079 12.5 0.1 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase ANAPC4_WD40 PF12894.7 GAN07968.1 - 6.1e-10 39.3 1.6 0.18 12.1 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAN07968.1 - 0.00022 21.1 3.7 0.64 10.0 0.1 4.3 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat WD40 PF00400.32 GAN07968.1 - 0.002 18.9 6.5 56 4.9 0.0 6.6 4 1 1 5 5 5 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 GAN07969.1 - 3.9e-12 46.3 11.6 6.8e-12 45.5 11.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN07969.1 - 1.1e-09 38.0 10.8 2e-09 37.2 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN07969.1 - 4.9e-09 35.8 5.1 9.2e-09 34.9 5.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAN07969.1 - 5.5e-07 29.8 8.5 1.4e-06 28.5 8.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAN07969.1 - 2.9e-06 27.2 3.2 2.9e-06 27.2 3.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAN07969.1 - 9.2e-06 25.4 9.2 1.7e-05 24.6 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN07969.1 - 2.5e-05 24.1 9.0 4.2e-05 23.4 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN07969.1 - 0.00045 20.0 8.7 0.00075 19.3 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 GAN07969.1 - 0.0012 18.6 5.2 0.0027 17.5 5.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 GAN07969.1 - 0.0041 16.7 7.5 0.0078 15.8 7.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAN07969.1 - 0.0054 16.8 8.6 0.048 13.7 8.6 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 GAN07969.1 - 0.014 15.6 8.1 0.03 14.5 8.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAN07969.1 - 0.017 15.0 10.0 0.031 14.1 10.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 GAN07969.1 - 0.55 10.1 5.5 1.2 9.1 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 GAN07969.1 - 1 9.4 11.0 4.3 7.5 11.0 2.1 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 GAN07969.1 - 9 6.5 12.8 11 6.3 10.7 2.1 1 1 1 2 2 2 0 RING-variant domain Aminotran_1_2 PF00155.21 GAN07970.1 - 2.1e-41 142.3 0.0 2.6e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAN07970.1 - 0.067 12.5 0.0 0.65 9.2 0.0 2.0 2 0 0 2 2 2 0 Beta-eliminating lyase Mcl1_mid PF12341.8 GAN07973.1 - 3e-88 296.0 0.0 4.4e-87 292.2 0.0 2.3 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 GAN07973.1 - 5.7e-19 68.1 14.2 0.00074 20.3 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN07973.1 - 1.9e-10 40.9 0.3 0.0069 16.7 0.1 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN07973.1 - 0.0023 17.3 1.7 0.007 15.7 0.1 2.4 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 GAN07973.1 - 0.0091 15.0 0.1 0.13 11.2 0.0 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAN07973.1 - 0.028 14.4 0.5 21 5.2 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SGL PF08450.12 GAN07973.1 - 0.26 10.8 2.4 4.3 6.8 0.0 3.0 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region DNA_pol_alpha_N PF12254.8 GAN07973.1 - 1.6 8.8 9.0 4.9 7.3 9.0 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal RNA_pol_Rpc34 PF05158.12 GAN07975.1 - 4.1e-85 286.1 0.0 5.4e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 GAN07975.1 - 0.018 15.2 0.6 0.089 13.0 0.2 2.1 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC RPA_C PF08784.11 GAN07975.1 - 0.041 14.5 0.5 0.23 12.2 0.1 2.2 2 0 0 2 2 2 0 Replication protein A C terminal Ribosomal_L37ae PF01780.19 GAN07976.1 - 2.6e-41 139.6 13.0 2.9e-41 139.5 13.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 GAN07976.1 - 0.00097 19.2 3.2 0.0014 18.7 3.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 GAN07976.1 - 0.0015 18.5 1.8 0.0023 17.9 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 GAN07976.1 - 0.014 15.4 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 GAN07976.1 - 0.022 14.4 2.9 2.9 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 GAN07976.1 - 0.036 14.0 3.2 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 GAN07976.1 - 0.12 12.7 2.9 4.5 7.7 3.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 GAN07976.1 - 0.93 9.6 5.6 4 7.5 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 GAN07976.1 - 4.2 8.0 7.3 2.4 8.7 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Gar1 PF04410.14 GAN07977.1 - 5.5e-39 133.4 0.1 6.8e-39 133.1 0.1 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region eIF-3c_N PF05470.12 GAN07978.1 - 0.00064 18.2 6.3 0.00064 18.2 6.3 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 GAN07978.1 - 0.0029 17.1 23.9 0.079 12.4 14.8 2.2 2 0 0 2 2 2 2 SDA1 Pox_Ag35 PF03286.14 GAN07978.1 - 0.0095 15.7 6.3 0.0095 15.7 6.3 2.7 3 0 0 3 3 3 1 Pox virus Ag35 surface protein DUF4695 PF15766.5 GAN07978.1 - 0.0096 16.1 0.8 0.0096 16.1 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4695) CPSF100_C PF13299.6 GAN07978.1 - 0.0097 16.1 8.9 0.75 10.0 3.3 2.2 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 GAN07978.1 - 0.016 13.4 25.2 0.0072 14.6 12.5 2.2 2 0 0 2 2 2 0 Nop14-like family BSP_II PF05432.11 GAN07978.1 - 0.033 13.9 32.3 0.58 9.8 32.9 2.1 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.12 GAN07978.1 - 0.055 12.4 18.3 0.1 11.5 1.8 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein Sec62 PF03839.16 GAN07978.1 - 0.074 12.6 3.3 5 6.6 1.1 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DNA_pol_phi PF04931.13 GAN07978.1 - 0.079 11.1 32.5 0.087 10.9 20.2 2.2 2 0 0 2 2 2 0 DNA polymerase phi Vfa1 PF08432.10 GAN07978.1 - 0.081 13.2 15.7 0.12 12.7 6.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Peroxin-13_N PF04088.13 GAN07978.1 - 0.24 11.7 0.4 10 6.4 0.1 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2722 PF10846.8 GAN07978.1 - 0.46 9.4 19.2 0.32 9.9 10.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3306 PF11748.8 GAN07978.1 - 0.51 11.2 13.3 5.5 7.9 5.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RPA43_OB PF17875.1 GAN07978.1 - 0.76 10.4 8.5 5.9 7.5 3.2 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I eIF-3_zeta PF05091.12 GAN07978.1 - 1 8.3 11.5 0.087 11.8 6.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PBP_sp32 PF07222.12 GAN07978.1 - 1.2 8.5 12.1 4.4 6.7 0.5 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF3381 PF11861.8 GAN07978.1 - 1.3 8.8 18.7 3.3 7.5 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Mak16 PF04874.14 GAN07978.1 - 1.8 9.2 23.6 1.8 9.2 1.5 2.8 2 0 0 2 2 2 0 Mak16 protein C-terminal region RPN2_C PF18004.1 GAN07978.1 - 2.3 8.1 14.7 2.5 8.0 5.4 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Gti1_Pac2 PF09729.9 GAN07978.1 - 2.4 8.2 9.5 3.2 7.8 0.3 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Rad54_N PF08658.10 GAN07978.1 - 2.8 8.1 10.9 2.6 8.2 0.7 2.5 2 0 0 2 2 2 0 Rad54 N terminal TRAP_alpha PF03896.16 GAN07978.1 - 2.9 7.0 17.7 2.3 7.3 8.6 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Fungal_trans_2 PF11951.8 GAN07978.1 - 4.1 6.1 8.6 0.11 11.3 0.8 2.2 1 1 0 2 2 2 0 Fungal specific transcription factor domain DAP PF15228.6 GAN07978.1 - 4.3 8.6 5.4 15 6.8 0.1 2.5 2 0 0 2 2 2 0 Death-associated protein Sporozoite_P67 PF05642.11 GAN07978.1 - 4.4 5.3 18.1 1.4 6.9 9.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PI3K_1B_p101 PF10486.9 GAN07978.1 - 5.5 4.6 17.0 2 6.1 7.3 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Connexin PF00029.19 GAN07978.1 - 9.2 5.9 5.6 10 5.8 0.6 2.2 2 0 0 2 2 2 0 Connexin AAA_2 PF07724.14 GAN07979.1 - 3.2e-40 138.1 0.0 2.5e-39 135.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAN07979.1 - 1.5e-15 57.8 0.1 6.2e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAN07979.1 - 2.3e-12 46.8 1.9 2.7e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAN07979.1 - 8.7e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAN07979.1 - 1.9e-06 27.4 0.2 0.00071 19.0 0.1 3.1 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GAN07979.1 - 0.00012 21.9 0.0 0.032 13.9 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 GAN07979.1 - 0.00013 22.2 4.4 0.0017 18.6 0.3 3.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAN07979.1 - 0.0002 21.2 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 GAN07979.1 - 0.0004 20.2 0.2 0.0097 15.7 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 GAN07979.1 - 0.0014 17.8 0.1 0.012 14.7 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_24 PF13479.6 GAN07979.1 - 0.0024 17.6 0.1 0.0081 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAN07979.1 - 0.0041 17.5 1.0 0.022 15.1 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 GAN07979.1 - 0.0041 17.2 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 GAN07979.1 - 0.0056 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAN07979.1 - 0.007 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 GAN07979.1 - 0.012 16.2 0.0 0.012 16.2 0.0 2.2 1 1 1 2 2 1 0 ABC transporter NACHT PF05729.12 GAN07979.1 - 0.012 15.5 0.2 0.065 13.1 0.0 2.3 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 GAN07979.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAN07979.1 - 0.021 15.0 2.2 0.039 14.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 GAN07979.1 - 0.022 14.2 0.0 0.062 12.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 GAN07979.1 - 0.024 13.7 0.2 0.047 12.7 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 GAN07979.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 GAN07979.1 - 0.047 13.5 0.1 0.14 12.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 GAN07979.1 - 0.094 13.1 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 GAN07979.1 - 0.13 12.1 0.3 0.88 9.4 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Swi3 PF07962.12 GAN07980.1 - 3.8e-21 74.9 0.2 6.1e-21 74.2 0.2 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 EamA PF00892.20 GAN07981.1 - 1.1e-24 87.1 33.1 3.4e-15 56.4 16.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAN07981.1 - 0.0018 17.7 2.7 0.0018 17.7 2.7 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF2593 PF10767.9 GAN07981.1 - 0.5 10.4 4.0 2.2 8.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2593) DUF5345 PF17280.2 GAN07981.1 - 0.75 9.8 3.1 0.9 9.6 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5345) LysM PF01476.20 GAN07982.1 - 1.4e-08 34.7 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain DDHD PF02862.17 GAN07982.1 - 0.005 17.0 2.6 0.0071 16.5 2.6 1.3 1 0 0 1 1 1 1 DDHD domain Otopetrin PF03189.13 GAN07982.1 - 0.033 13.0 1.2 0.032 13.1 1.2 1.2 1 0 0 1 1 1 0 Otopetrin PCM1_C PF15717.5 GAN07982.1 - 0.055 12.2 11.2 0.072 11.8 11.2 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Membralin PF09746.9 GAN07982.1 - 0.13 11.2 3.7 0.15 11.0 3.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein Hydin_ADK PF17213.3 GAN07982.1 - 0.14 12.4 12.1 0.23 11.7 12.1 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NPR3 PF03666.13 GAN07982.1 - 0.23 10.2 10.2 0.28 9.9 10.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CAC1F_C PF16885.5 GAN07982.1 - 0.25 10.9 8.9 0.33 10.6 8.9 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Presenilin PF01080.17 GAN07982.1 - 0.3 9.8 8.3 0.41 9.3 8.3 1.2 1 0 0 1 1 1 0 Presenilin KAR9 PF08580.10 GAN07982.1 - 0.36 9.3 13.7 0.39 9.2 13.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ALMT PF11744.8 GAN07982.1 - 0.42 9.4 11.8 0.56 9.0 11.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Dicty_REP PF05086.12 GAN07982.1 - 0.5 8.3 21.6 0.64 7.9 21.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF572 PF04502.13 GAN07982.1 - 0.51 9.9 19.9 0.7 9.5 19.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Zip PF02535.22 GAN07982.1 - 0.63 9.2 2.9 0.74 9.0 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 GAN07982.1 - 0.8 8.2 14.7 0.93 8.0 14.7 1.0 1 0 0 1 1 1 0 Macoilin family Tim54 PF11711.8 GAN07982.1 - 1.8 7.3 11.1 2.6 6.7 11.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MCM_bind PF09739.9 GAN07982.1 - 1.9 6.8 12.4 2.4 6.5 12.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF5427 PF10310.9 GAN07982.1 - 3.2 6.6 17.3 4.1 6.2 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RR_TM4-6 PF06459.12 GAN07982.1 - 4.9 6.9 15.1 7.1 6.4 15.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DAG_kinase_N PF14513.6 GAN07982.1 - 6.9 6.8 12.0 12 6.0 12.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CPSF100_C PF13299.6 GAN07982.1 - 8.6 6.5 13.5 16 5.7 13.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GREB1 PF15782.5 GAN07982.1 - 8.9 3.3 15.8 11 3.0 15.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Paramyxo_ncap PF00973.19 GAN07982.1 - 9.6 5.0 13.8 12 4.6 13.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ofd1_CTDD PF10637.9 GAN07984.1 - 4.7e-75 252.3 0.0 2.1e-69 233.7 0.0 2.6 3 1 0 3 3 3 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 GAN07984.1 - 9.5e-32 109.5 0.0 2e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAN07984.1 - 1.4e-16 61.2 0.0 4.4e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TBPIP PF07106.13 GAN07986.1 - 1.3e-13 50.7 1.9 1.7e-13 50.3 0.3 2.0 2 0 0 2 2 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 GAN07986.1 - 1.5e-09 37.8 0.0 1.5e-09 37.8 0.0 2.5 4 0 0 4 4 1 1 Leucine zipper with capping helix domain UPF0242 PF06785.11 GAN07986.1 - 5e-05 23.5 3.9 6.1e-05 23.2 3.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Syntaxin PF00804.25 GAN07986.1 - 0.0022 17.7 2.5 0.0033 17.1 2.5 1.3 1 0 0 1 1 1 1 Syntaxin FlgN PF05130.12 GAN07986.1 - 0.0029 18.1 2.8 0.0029 18.1 2.8 1.7 2 0 0 2 2 1 1 FlgN protein DUF4140 PF13600.6 GAN07986.1 - 0.0039 17.6 0.4 0.0039 17.6 0.4 2.2 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) Taxilin PF09728.9 GAN07986.1 - 0.0075 15.5 8.5 0.014 14.5 8.5 1.4 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Fez1 PF06818.15 GAN07986.1 - 0.013 16.0 5.8 0.017 15.6 5.8 1.3 1 0 0 1 1 1 0 Fez1 DUF3584 PF12128.8 GAN07986.1 - 0.016 12.8 6.6 0.017 12.7 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 GAN07986.1 - 0.018 14.0 5.3 0.027 13.4 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Ax_dynein_light PF10211.9 GAN07986.1 - 0.019 14.9 4.6 0.035 14.1 4.6 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain YabA PF06156.13 GAN07986.1 - 0.022 15.4 1.5 0.022 15.4 1.5 2.5 2 1 1 3 3 2 0 Initiation control protein YabA ZapB PF06005.12 GAN07986.1 - 0.03 14.8 12.0 1.1 9.7 2.5 2.6 1 1 1 2 2 2 0 Cell division protein ZapB DUF2205 PF10224.9 GAN07986.1 - 0.042 13.8 1.0 0.042 13.8 1.0 2.2 2 0 0 2 2 2 0 Short coiled-coil protein DUF3106 PF11304.8 GAN07986.1 - 0.048 14.1 0.9 0.048 14.1 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) DivIC PF04977.15 GAN07986.1 - 0.086 12.6 12.2 1.1 9.1 2.2 2.7 1 1 1 2 2 2 0 Septum formation initiator Penicillinase_R PF03965.16 GAN07986.1 - 0.087 13.2 2.5 0.48 10.8 0.1 2.4 2 1 1 3 3 2 0 Penicillinase repressor Hemerythrin PF01814.23 GAN07986.1 - 0.099 13.3 2.4 5.8 7.6 2.0 2.8 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain FUSC PF04632.12 GAN07986.1 - 0.12 10.9 0.2 0.15 10.6 0.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_1 PF00170.21 GAN07986.1 - 0.14 12.3 8.7 2.7 8.2 0.9 2.7 2 0 0 2 2 2 0 bZIP transcription factor Laminin_II PF06009.12 GAN07986.1 - 0.16 12.0 4.4 0.26 11.3 4.4 1.3 1 0 0 1 1 1 0 Laminin Domain II PCRF PF03462.18 GAN07986.1 - 0.17 11.7 7.6 0.26 11.1 7.3 1.4 1 1 0 1 1 1 0 PCRF domain bZIP_2 PF07716.15 GAN07986.1 - 0.23 11.6 10.6 0.12 12.5 2.3 2.7 2 0 0 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 GAN07986.1 - 0.26 11.7 2.6 1.8 9.0 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 GAN07986.1 - 0.28 12.1 10.9 1.9 9.5 3.4 2.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spore_III_AB PF09548.10 GAN07986.1 - 0.4 10.8 4.8 0.31 11.1 0.4 2.4 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TPR_MLP1_2 PF07926.12 GAN07986.1 - 0.4 10.7 14.1 0.87 9.6 2.5 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 GAN07986.1 - 0.68 9.2 5.2 0.82 9.0 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5094 PF17015.5 GAN07986.1 - 0.68 10.0 8.7 1 9.5 8.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) TMPIT PF07851.13 GAN07986.1 - 0.76 9.0 2.7 0.88 8.8 2.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF2433 PF10360.9 GAN07986.1 - 0.78 9.8 3.5 1.2 9.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) FapA PF03961.13 GAN07986.1 - 0.87 8.1 8.3 1.3 7.6 8.1 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Nnf1 PF03980.14 GAN07986.1 - 0.91 9.9 10.2 6.2 7.2 1.6 2.4 1 1 1 2 2 2 0 Nnf1 Snapin_Pallidin PF14712.6 GAN07986.1 - 1.4 9.4 7.6 7.1 7.1 7.7 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Mto2_bdg PF12808.7 GAN07986.1 - 1.4 9.2 11.6 1.9 8.9 5.4 2.6 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region AAA_23 PF13476.6 GAN07986.1 - 1.5 9.3 9.6 2.4 8.6 9.6 1.3 1 0 0 1 1 1 0 AAA domain Mod_r PF07200.13 GAN07986.1 - 1.7 8.8 11.8 4.9 7.3 10.8 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Seryl_tRNA_N PF02403.22 GAN07986.1 - 1.8 8.8 14.1 0.31 11.3 6.0 2.5 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.13 GAN07986.1 - 2 9.2 9.6 1.1 10.1 4.5 2.6 3 0 0 3 3 3 0 Occludin homology domain TipAS PF07739.13 GAN07986.1 - 3.2 8.3 6.4 5.8 7.5 3.7 2.5 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Herpes_BLRF2 PF05812.12 GAN07986.1 - 3.3 7.9 12.8 0.95 9.6 3.1 2.8 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein Prominin PF05478.11 GAN07986.1 - 3.9 5.3 4.5 5.2 4.9 4.5 1.2 1 0 0 1 1 1 0 Prominin Prefoldin PF02996.17 GAN07986.1 - 5.5 6.9 10.5 2.6 8.0 1.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit HALZ PF02183.18 GAN07986.1 - 7.3 6.9 11.7 15 5.9 1.2 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper BMFP PF04380.13 GAN07986.1 - 8.4 7.0 10.8 5.9 7.5 4.9 3.4 3 2 2 5 5 3 0 Membrane fusogenic activity Kelch_5 PF13854.6 GAN07987.1 - 1.7e-17 63.0 0.0 0.00021 21.2 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 GAN07987.1 - 5.6e-17 61.0 0.1 6e-05 22.8 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 GAN07987.1 - 4.5e-16 58.5 0.4 0.0012 19.1 0.0 4.9 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAN07987.1 - 6.6e-14 51.8 12.4 4.2e-07 30.1 0.0 7.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN07987.1 - 3.2e-12 45.8 0.2 0.023 14.3 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAN07987.1 - 9.5e-11 41.5 6.6 0.0032 17.4 0.0 5.2 5 1 0 5 5 5 3 Galactose oxidase, central domain BTB PF00651.31 GAN07987.1 - 2.7e-10 40.4 1.7 0.00064 19.9 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain Pkinase PF00069.25 GAN07988.1 - 1e-35 123.4 1.5 2.1e-11 43.7 0.0 4.7 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAN07988.1 - 5.8e-17 61.8 0.0 2.3e-05 23.8 0.0 4.4 5 0 0 5 5 5 3 Protein tyrosine kinase Kdo PF06293.14 GAN07988.1 - 0.0069 15.8 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family OmpH PF03938.14 GAN07988.1 - 0.025 14.9 14.3 0.066 13.5 14.3 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4355 PF14265.6 GAN07988.1 - 0.041 14.1 9.8 0.12 12.7 9.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TcpS PF17456.2 GAN07988.1 - 0.078 13.0 3.9 0.17 12.0 3.9 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S CEP63 PF17045.5 GAN07988.1 - 0.081 12.8 13.2 0.15 11.9 13.2 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa AAA_23 PF13476.6 GAN07988.1 - 0.16 12.4 7.4 0.045 14.3 3.2 2.1 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 GAN07988.1 - 0.29 11.2 11.8 0.63 10.1 11.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 GAN07988.1 - 0.31 11.3 10.5 0.8 9.9 10.5 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Lipoprotein_6 PF01441.19 GAN07988.1 - 0.44 10.5 5.3 0.13 12.3 2.1 1.6 2 0 0 2 2 2 0 Lipoprotein TMPIT PF07851.13 GAN07988.1 - 0.95 8.6 7.5 1.9 7.7 7.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 GAN07988.1 - 1.3 8.5 7.1 1.3 8.6 3.8 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3552 PF12072.8 GAN07988.1 - 2.8 7.3 12.2 5 6.5 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3452 PF11934.8 GAN07988.1 - 3.4 7.2 7.2 15 5.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) FapA PF03961.13 GAN07988.1 - 5.1 5.6 7.3 7.9 5.0 7.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SH3_9 PF14604.6 GAN07989.1 - 1.5e-09 37.6 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN07989.1 - 2.1e-07 30.4 0.0 4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN07989.1 - 0.00021 20.9 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Adeno_E3_CR2 PF02439.15 GAN07989.1 - 0.0038 16.9 2.9 0.0038 16.9 2.9 1.9 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 MLANA PF14991.6 GAN07989.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A Podoplanin PF05808.11 GAN07989.1 - 0.13 12.4 0.5 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 Podoplanin DUF347 PF03988.12 GAN07989.1 - 0.31 11.3 1.5 0.96 9.7 0.3 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF4690 PF15756.5 GAN07989.1 - 0.75 10.4 0.0 0.75 10.4 0.0 3.0 3 1 0 3 3 3 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 GAN07989.1 - 1.1 9.7 16.8 1 9.8 12.2 3.1 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 bZIP_1 PF00170.21 GAN07990.1 - 8.5e-10 38.6 5.5 8.5e-10 38.6 5.5 1.7 2 0 0 2 2 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN07990.1 - 3e-07 30.4 5.5 3e-07 30.4 5.5 2.4 2 0 0 2 2 1 1 Basic region leucine zipper TFIIA PF03153.13 GAN07990.1 - 0.0059 16.7 23.2 0.0063 16.6 23.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit bZIP_Maf PF03131.17 GAN07990.1 - 0.011 16.2 1.4 0.011 16.2 1.4 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor Peptidase_S64 PF08192.11 GAN07990.1 - 0.099 11.1 11.4 0.11 10.9 11.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 SURF6 PF04935.12 GAN07990.1 - 0.13 12.0 14.0 0.18 11.6 14.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 Ndc1_Nup PF09531.10 GAN07990.1 - 0.15 10.8 9.1 0.15 10.7 9.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MCM3AP_GANP PF16769.5 GAN07990.1 - 0.22 9.8 14.9 0.26 9.5 14.9 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP Miga PF10265.9 GAN07990.1 - 0.36 9.8 10.2 0.43 9.5 10.2 1.0 1 0 0 1 1 1 0 Mitoguardin DUF3801 PF12687.7 GAN07990.1 - 4.7 7.2 15.4 6.4 6.8 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PAT1 PF09770.9 GAN07990.1 - 7.3 4.7 22.1 8.5 4.5 22.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3488 PF11992.8 GAN07990.1 - 8.2 5.3 5.8 10 5.0 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) ALMT PF11744.8 GAN07990.1 - 8.6 5.1 11.3 11 4.7 11.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 GAN07990.1 - 8.9 5.0 16.2 12 4.6 16.2 1.1 1 0 0 1 1 1 0 Presenilin Vac7 PF12751.7 GAN07991.1 - 6.1e-08 32.5 0.8 6.1e-08 32.5 0.8 2.6 1 1 1 2 2 2 1 Vacuolar segregation subunit 7 PH PF00169.29 GAN07992.1 - 8.4e-15 55.2 0.2 1.9e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAN07992.1 - 0.0001 22.7 2.9 0.0019 18.6 2.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAN07992.1 - 0.0014 18.9 0.3 0.51 10.6 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 GAN07992.1 - 0.0052 17.1 0.6 0.033 14.6 0.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain T4_gp9_10 PF07880.11 GAN07992.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein G-gamma PF00631.22 GAN07993.1 - 1.3e-17 63.5 0.0 1.4e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain GntR PF00392.21 GAN07993.1 - 0.13 11.9 0.2 0.24 11.1 0.2 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family Serinc PF03348.15 GAN07994.1 - 4e-157 523.6 9.8 4.6e-157 523.4 9.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF5480 PF17576.2 GAN07994.1 - 0.03 14.3 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5480) DUF218 PF02698.17 GAN07995.1 - 0.00051 20.1 0.0 0.00094 19.2 0.0 1.4 1 1 0 1 1 1 1 DUF218 domain LON_substr_bdg PF02190.16 GAN07996.1 - 1.1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 GAN07996.1 - 1.4e-08 34.8 27.6 1.1e-05 25.5 9.9 2.8 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAN07996.1 - 1.8e-07 31.1 24.2 0.00028 20.8 7.8 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_10 PF16685.5 GAN07996.1 - 5.2e-07 29.7 17.7 0.00017 21.7 4.4 2.4 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 GAN07996.1 - 7.2e-06 25.8 19.8 0.0089 15.9 6.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN07996.1 - 5.2e-05 23.0 22.1 0.017 15.0 7.8 3.0 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN07996.1 - 0.00016 21.5 24.0 0.017 15.0 7.1 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAN07996.1 - 0.00045 20.0 24.5 0.0057 16.5 7.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN07996.1 - 0.012 15.4 22.8 0.26 11.2 8.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN07996.1 - 0.18 12.2 23.3 0.34 11.3 7.0 2.6 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.6 GAN07996.1 - 3.8 7.4 13.9 5.2 6.9 2.6 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Cu-oxidase_2 PF07731.14 GAN07997.1 - 4.8e-42 142.9 9.6 1.1e-39 135.3 0.9 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAN07997.1 - 2.2e-36 124.5 1.4 2.2e-36 124.5 1.4 3.8 3 2 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 GAN07997.1 - 5.6e-34 117.6 3.2 2.7e-33 115.3 1.2 2.5 2 0 0 2 2 2 1 Multicopper oxidase FTR1 PF03239.14 GAN07998.1 - 1.9e-74 250.6 17.2 2.3e-74 250.3 17.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family MgtE PF01769.16 GAN07998.1 - 0.54 10.7 15.7 2.3 8.6 3.1 3.1 3 0 0 3 3 3 0 Divalent cation transporter Phage_holin_3_6 PF07332.11 GAN07998.1 - 5.3 7.1 17.4 0.26 11.3 0.6 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III BK_channel_a PF03493.18 GAN07999.1 - 8.7e-26 90.0 0.1 5.4e-25 87.4 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 GAN07999.1 - 1.9e-14 53.4 1.9 5.3e-14 51.9 1.9 1.7 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 GAN07999.1 - 0.00011 22.4 0.0 0.36 11.1 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.31 GAN07999.1 - 0.041 13.1 13.5 0.084 12.1 13.5 1.5 1 0 0 1 1 1 0 Ion transport protein DDE_3 PF13358.6 GAN08001.1 - 7.2e-24 84.2 0.0 8.2e-20 71.0 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_28 PF13518.6 GAN08001.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 GAN08001.1 - 0.11 13.1 0.0 0.37 11.4 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain rve PF00665.26 GAN08001.1 - 0.12 12.6 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain NAD_binding_10 PF13460.6 GAN08003.1 - 6.8e-22 78.2 0.0 8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN08003.1 - 2.3e-06 27.3 0.9 5.3e-06 26.2 0.6 1.8 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.20 GAN08003.1 - 0.00043 20.4 0.4 0.001 19.2 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 GAN08003.1 - 0.001 18.6 0.1 0.0021 17.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAN08003.1 - 0.0018 18.8 0.3 0.0042 17.6 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAN08003.1 - 0.0026 18.2 0.5 0.0095 16.4 0.3 2.0 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 GAN08003.1 - 0.028 13.8 0.6 0.082 12.2 0.6 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 GAN08003.1 - 0.031 14.2 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shugoshin_N PF07558.11 GAN08003.1 - 0.1 12.5 2.2 2.3 8.1 0.2 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region FTCD_C PF04961.12 GAN08003.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase RmlD_sub_bind PF04321.17 GAN08003.1 - 0.12 11.5 0.2 0.2 10.7 0.2 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Asn_synthase PF00733.21 GAN08004.1 - 1.3e-16 61.2 0.2 5e-10 39.6 0.4 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GAN08004.1 - 1.8e-07 31.1 0.0 5.6e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAN08004.1 - 0.019 15.1 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 Glutamine amidotransferase domain NUDIX PF00293.28 GAN08005.1 - 9.4e-11 41.9 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AdoMet_MTase PF07757.13 GAN08006.1 - 4.5e-37 126.8 0.1 7.4e-37 126.1 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 GAN08006.1 - 0.00048 20.1 2.2 0.0012 18.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08006.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN08006.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAN08006.1 - 0.012 16.4 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAN08006.1 - 0.017 15.8 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08006.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 GAN08006.1 - 0.022 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 GAN08006.1 - 0.048 14.4 0.0 0.18 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Podoplanin PF05808.11 GAN08007.1 - 0.0097 16.0 6.6 0.0097 16.0 6.6 2.6 1 1 1 2 2 2 1 Podoplanin Gly-zipper_Omp PF13488.6 GAN08007.1 - 5.9 7.0 16.0 0.84 9.7 4.1 2.6 2 0 0 2 2 2 0 Glycine zipper F-box-like PF12937.7 GAN08008.1 - 1.4e-07 31.2 0.2 7.1e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN08008.1 - 0.00059 19.6 0.4 0.005 16.7 0.0 2.5 3 0 0 3 3 3 1 F-box domain SAM_2 PF07647.17 GAN08008.1 - 0.13 12.4 0.7 0.86 9.8 0.3 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) eIF-5_eIF-2B PF01873.17 GAN08009.1 - 8.7e-44 148.1 1.6 3.2e-43 146.3 0.4 2.1 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 GAN08009.1 - 1.7e-20 72.9 0.1 1.7e-20 72.9 0.1 2.4 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Sel1 PF08238.12 GAN08010.1 - 5.6e-103 335.0 91.2 4.3e-08 33.6 0.5 27.9 29 0 0 29 29 29 21 Sel1 repeat TPR_16 PF13432.6 GAN08010.1 - 0.0062 17.2 39.4 0.2 12.3 3.9 10.8 12 0 0 12 12 12 2 Tetratricopeptide repeat RTP1_C1 PF10363.9 GAN08010.1 - 0.012 15.7 0.4 0.087 13.0 0.0 2.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_12 PF13424.6 GAN08010.1 - 0.044 14.1 0.3 0.044 14.1 0.3 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN08010.1 - 0.3 11.8 32.6 2.9 8.7 0.0 11.9 13 1 0 13 13 13 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN08010.1 - 3.2 8.0 26.6 0.32 11.3 0.9 7.2 7 0 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAN08010.1 - 3.5 7.6 12.8 13 5.8 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat IF-2B PF01008.17 GAN08013.1 - 2.6e-17 63.0 0.1 8.3e-17 61.3 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Imm49 PF15575.6 GAN08013.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 49 DUF5485 PF17586.2 GAN08013.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5485) TFIID_30kDa PF03540.13 GAN08014.1 - 1.2e-23 82.8 0.2 1.8e-23 82.2 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 GAN08014.1 - 0.0072 16.3 0.1 0.56 10.3 0.1 2.2 1 1 0 1 1 1 1 Bromodomain associated SLX9 PF15341.6 GAN08014.1 - 0.1 13.0 0.1 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF4112 PF13430.6 GAN08015.1 - 1.1e-34 118.9 1.5 2e-34 118.0 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) WD40 PF00400.32 GAN08015.1 - 2.3e-11 44.1 8.4 0.056 14.3 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08015.1 - 7.7e-06 26.1 0.0 0.087 13.1 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAN08015.1 - 0.00028 20.6 0.0 0.016 14.8 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain Pro_CA PF00484.19 GAN08016.1 - 9.3e-51 172.2 1.3 1.3e-50 171.7 1.3 1.2 1 0 0 1 1 1 1 Carbonic anhydrase zf-C2H2 PF00096.26 GAN08017.1 - 2.1e-21 75.1 23.2 5.3e-07 29.7 0.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN08017.1 - 5.4e-21 74.0 23.2 3.5e-06 27.2 2.2 4.6 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN08017.1 - 6.4e-11 42.1 21.6 0.0068 17.2 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN08017.1 - 0.00021 21.5 5.6 4.6 7.6 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 GAN08017.1 - 0.012 16.2 5.3 1.2 9.8 0.2 3.6 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-TRAF PF02176.18 GAN08017.1 - 0.027 15.1 15.0 0.039 14.6 2.6 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 GAN08017.1 - 0.047 13.5 0.6 0.047 13.5 0.6 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 GAN08017.1 - 0.05 14.0 8.4 35 5.0 0.3 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 GAN08017.1 - 0.096 13.0 13.7 0.21 11.9 0.9 3.1 2 1 1 3 3 3 0 C2H2-type zinc ribbon CHORD PF04968.12 GAN08017.1 - 0.12 13.1 8.6 3.4 8.5 0.1 3.9 3 1 0 3 3 3 0 CHORD zf-C2H2_aberr PF17017.5 GAN08017.1 - 0.95 9.6 8.7 7.5 6.7 0.1 3.7 2 2 1 3 3 3 0 Aberrant zinc-finger Aha1_N PF09229.11 GAN08019.1 - 5.3e-39 133.6 0.2 8.9e-39 132.8 0.2 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 GAN08019.1 - 7.6e-19 68.2 0.4 1.3e-18 67.4 0.4 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein LTXXQ PF07813.12 GAN08019.1 - 0.17 12.6 0.1 0.27 12.0 0.1 1.4 1 0 0 1 1 1 0 LTXXQ motif family protein Ribosomal_60s PF00428.19 GAN08019.1 - 0.27 11.8 1.3 0.59 10.8 1.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein WD40 PF00400.32 GAN08020.1 - 4.7e-08 33.6 2.9 0.0002 22.1 1.7 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08020.1 - 1.6e-05 25.1 0.0 0.089 13.1 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain YokU PF14122.6 GAN08020.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin WD40 PF00400.32 GAN08021.1 - 0.01 16.7 0.3 0.23 12.4 0.2 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat fn3_2 PF16893.5 GAN08022.1 - 1e-34 118.5 0.1 2e-34 117.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 GAN08022.1 - 2.5e-28 97.7 0.2 4e-28 97.1 0.2 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 GAN08022.1 - 6.1e-11 42.1 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 GAN08022.1 - 1.1e-10 41.8 0.0 2.9e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 GAN08022.1 - 4.3e-05 23.8 0.0 0.0002 21.7 0.0 2.1 2 1 0 2 2 2 1 Fibronectin type III domain BRCT_2 PF16589.5 GAN08022.1 - 8.2e-05 22.9 0.0 0.00024 21.4 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 GAN08022.1 - 0.00072 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_3 PF18428.1 GAN08022.1 - 0.054 13.6 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain N_BRCA1_IG PF16158.5 GAN08022.1 - 0.092 13.5 0.0 0.56 11.0 0.0 2.1 2 0 0 2 2 2 0 Ig-like domain from next to BRCA1 gene DUF4637 PF15470.6 GAN08023.1 - 0.034 13.9 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2318 PF10080.9 GAN08023.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF1922 PF09082.10 GAN08023.1 - 0.4 11.0 2.5 2.1 8.7 2.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1922) BTB_2 PF02214.22 GAN08024.1 - 9.3e-12 45.1 0.1 8.2e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 GAN08024.1 - 0.0011 19.1 0.0 0.39 11.0 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain VirArc_Nuclease PF12187.8 GAN08024.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral/Archaeal nuclease Glu-tRNAGln PF02686.15 GAN08025.1 - 0.46 10.8 3.0 0.48 10.8 0.1 2.6 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit IF-2B PF01008.17 GAN08026.1 - 7.1e-63 212.4 1.4 1.7e-62 211.2 1.4 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family XAP5 PF04921.14 GAN08026.1 - 0.33 10.7 3.1 0.58 9.9 3.1 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator DDE_Tnp_1_2 PF13586.6 GAN08027.1 - 0.00011 22.5 0.2 0.00022 21.5 0.0 1.6 2 0 0 2 2 2 1 Transposase DDE domain Peptidase_M17 PF00883.21 GAN08030.1 - 8.3e-61 206.0 0.0 1.1e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain GTP_EFTU PF00009.27 GAN08031.1 - 3e-21 75.8 0.0 6.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAN08031.1 - 6.2e-08 32.9 0.8 1.9e-07 31.4 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 GAN08031.1 - 0.0005 20.4 2.5 0.001 19.3 1.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GAN08031.1 - 0.0053 16.8 0.4 0.025 14.6 0.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 GAN08031.1 - 0.05 13.1 0.3 3.7 7.0 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family DUF2577 PF10844.8 GAN08031.1 - 0.09 13.0 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Pox_Ag35 PF03286.14 GAN08032.1 - 0.3 10.9 6.8 0.45 10.3 6.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 GAN08032.1 - 0.38 10.1 9.0 0.51 9.7 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP1_TM PF14812.6 GAN08032.1 - 8.3 6.9 7.7 1.3 9.4 3.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CoA_binding_2 PF13380.6 GAN08033.1 - 1.8e-31 109.0 0.0 2.2e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_38N PF01074.22 GAN08034.1 - 2.1e-86 289.9 0.9 2.1e-86 289.9 0.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAN08034.1 - 7.7e-60 202.6 0.2 1.3e-59 201.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Ribosomal_S26e PF01283.19 GAN08034.1 - 7e-52 174.4 9.3 1.4e-51 173.5 9.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S26e Alpha-mann_mid PF09261.11 GAN08034.1 - 7.1e-21 74.2 0.0 1.7e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAN08034.1 - 5.5e-14 52.0 0.2 1.7e-13 50.5 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Folliculin PF11704.8 GAN08035.1 - 3.1e-44 151.1 0.2 6.6e-44 150.0 0.2 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Pyrid_oxidase_2 PF13883.6 GAN08035.1 - 1.4e-28 100.0 0.1 1.4e-28 100.0 0.1 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CBFD_NFYB_HMF PF00808.23 GAN08036.1 - 4.8e-13 49.2 0.0 8.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAN08036.1 - 0.01 16.2 0.0 0.01 16.2 0.0 2.7 2 1 0 2 2 1 0 Core histone H2A/H2B/H3/H4 BUD22 PF09073.10 GAN08036.1 - 0.013 14.9 21.0 0.014 14.7 21.0 1.1 1 0 0 1 1 1 0 BUD22 DUF5427 PF10310.9 GAN08036.1 - 0.043 12.8 16.3 0.049 12.6 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RNA_pol_3_Rpc31 PF11705.8 GAN08036.1 - 0.14 12.4 28.1 0.19 12.0 28.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF913 PF06025.12 GAN08036.1 - 0.33 9.9 10.1 0.51 9.2 10.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 GAN08036.1 - 0.5 9.8 20.7 0.65 9.4 20.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 GAN08036.1 - 0.82 9.0 30.8 0.93 8.8 30.8 1.1 1 0 0 1 1 1 0 SDA1 AAA_23 PF13476.6 GAN08036.1 - 1.1 9.7 14.9 1.3 9.5 14.9 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 GAN08036.1 - 1.9 8.5 5.6 2.4 8.1 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.12 GAN08036.1 - 2.2 6.4 30.3 2.5 6.2 30.3 1.1 1 0 0 1 1 1 0 Nop14-like family PA26 PF04636.13 GAN08036.1 - 4.3 6.2 10.0 5.2 5.9 10.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ALMT PF11744.8 GAN08036.1 - 4.7 5.9 9.6 5.2 5.8 9.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter VIR_N PF15912.5 GAN08036.1 - 6.7 6.2 15.1 8.3 5.9 15.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal GST_N_3 PF13417.6 GAN08037.1 - 3.2e-19 69.1 0.1 5.2e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAN08037.1 - 2.1e-18 66.4 0.1 3.3e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN08037.1 - 5.6e-14 52.2 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAN08037.1 - 3.3e-07 30.4 0.0 6.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN08037.1 - 0.0068 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN08037.1 - 0.018 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAN08037.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Vps36_ESCRT-II PF11605.8 GAN08038.1 - 0.023 14.9 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AphA_like PF14557.6 GAN08038.1 - 0.13 11.9 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Nebulin PF00880.18 GAN08039.1 - 0.0086 16.0 0.0 0.59 10.1 0.0 2.5 2 0 0 2 2 2 1 Nebulin repeat Gal4_dimer PF03902.13 GAN08039.1 - 0.098 12.8 0.1 0.31 11.2 0.1 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain CRA PF06589.11 GAN08039.1 - 1.2 9.3 5.3 0.14 12.3 0.5 1.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Peptidase_M1 PF01433.20 GAN08040.1 - 9.5e-84 280.3 4.0 1.8e-83 279.4 4.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAN08040.1 - 9.6e-71 238.9 1.7 1.7e-69 234.8 0.6 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAN08040.1 - 1e-54 185.5 0.9 1.9e-54 184.7 0.9 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 GAN08040.1 - 0.1 12.7 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 Pyr_redox_2 PF07992.14 GAN08042.1 - 5.5e-51 173.5 0.0 6.8e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN08042.1 - 3.6e-11 43.5 0.0 2.7e-10 40.6 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN08042.1 - 5.2e-05 22.6 0.1 0.096 11.9 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN08042.1 - 0.064 12.0 0.5 0.77 8.4 0.0 2.2 1 1 1 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 GAN08042.1 - 0.14 12.2 1.7 10 6.1 0.5 3.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pex19 PF04614.12 GAN08043.1 - 4.9e-67 226.2 17.8 4.9e-67 226.2 17.8 1.8 2 0 0 2 2 2 1 Pex19 protein family CAP_N PF01213.19 GAN08043.1 - 0.012 15.1 1.0 0.021 14.3 1.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Prominin PF05478.11 GAN08043.1 - 0.093 10.7 0.5 0.16 9.9 0.5 1.3 1 0 0 1 1 1 0 Prominin DASH_Spc34 PF08657.10 GAN08043.1 - 0.14 12.0 4.7 0.3 10.9 4.3 1.8 1 1 1 2 2 2 0 DASH complex subunit Spc34 T2SSF PF00482.23 GAN08043.1 - 0.2 11.6 0.7 5.9 6.9 0.0 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F LTXXQ PF07813.12 GAN08044.1 - 0.045 14.5 6.2 0.12 13.0 0.3 2.2 1 1 1 2 2 2 0 LTXXQ motif family protein MADF_DNA_bdg PF10545.9 GAN08045.1 - 0.041 14.2 4.2 1.8 8.9 0.2 3.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3482 PF11981.8 GAN08045.1 - 2.2 7.6 4.7 5.5 6.3 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3482) Csm1_N PF18504.1 GAN08045.1 - 2.7 8.4 14.4 0.35 11.2 1.2 3.7 3 0 0 3 3 3 0 Csm1 N-terminal domain Ribosomal_L30_N PF08079.12 GAN08046.1 - 0.00077 19.7 2.8 0.00077 19.7 2.8 2.0 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GAN08047.1 - 3.3e-18 65.3 1.7 6e-18 64.5 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAN08047.1 - 1.1e-15 57.6 4.5 2.3e-15 56.6 4.5 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain YqzH PF14164.6 GAN08048.1 - 0.64 10.1 7.0 32 4.7 0.1 3.6 3 0 0 3 3 3 0 YqzH-like protein O-antigen_lig PF13425.6 GAN08048.1 - 0.71 8.6 1.7 0.88 8.3 1.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DNA_pol3_a_NII PF11490.8 GAN08048.1 - 1.3 8.9 10.2 1.7 8.5 0.6 2.5 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Ribosomal_L14e PF01929.17 GAN08049.1 - 4e-29 100.9 4.8 6.2e-29 100.3 4.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 GAN08049.1 - 0.0011 18.9 0.3 0.0027 17.6 0.3 1.7 1 0 0 1 1 1 1 KOW motif EST1_DNA_bind PF10373.9 GAN08050.1 - 4.7e-21 75.5 0.8 1.5e-20 73.8 0.8 2.0 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 GAN08050.1 - 5.3e-07 30.3 0.1 5.3e-07 30.3 0.1 3.0 3 0 0 3 3 3 1 Telomerase activating protein Est1 PIN_4 PF13638.6 GAN08050.1 - 3e-06 27.6 7.7 0.00015 22.1 2.0 3.6 2 1 0 2 2 2 1 PIN domain TPR_17 PF13431.6 GAN08050.1 - 0.073 13.5 0.0 0.29 11.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Merozoite_SPAM PF07133.11 GAN08050.1 - 0.33 10.9 21.1 1.1 9.2 21.1 1.9 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Lzipper-MIP1 PF14389.6 GAN08050.1 - 0.38 11.1 2.9 1.8 8.9 1.4 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Lactamase_B_6 PF16661.5 GAN08051.1 - 2.6e-68 229.3 0.1 4.9e-68 228.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 GAN08051.1 - 2.4e-30 105.9 1.3 1.8e-27 96.6 0.0 2.6 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 GAN08051.1 - 3.9e-21 75.4 0.1 1.4e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 GAN08051.1 - 9.4e-11 41.5 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 GAN08051.1 - 1.6e-07 31.5 0.1 3.2e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN08051.1 - 5.2e-06 26.1 0.1 9.3e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GAN08051.1 - 0.066 12.4 0.4 0.31 10.2 0.4 2.0 1 1 0 1 1 1 0 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 GAN08051.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TERF2_RBM PF16772.5 GAN08052.1 - 0.0046 16.3 0.2 0.014 14.8 0.2 1.8 1 0 0 1 1 1 1 Telomeric repeat-binding factor 2 Rap1-binding motif TMEM52 PF14979.6 GAN08052.1 - 0.36 10.8 12.3 0.098 12.6 4.2 2.9 2 1 1 3 3 3 0 Transmembrane 52 Fe-S_biosyn PF01521.20 GAN08054.1 - 1e-20 74.0 0.0 1.3e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SET PF00856.28 GAN08055.1 - 9.6e-18 65.1 0.1 9.6e-18 65.1 0.1 4.1 3 2 0 3 3 3 1 SET domain AWS PF17907.1 GAN08055.1 - 8.5e-10 38.5 10.6 8.5e-10 38.5 10.6 2.5 2 0 0 2 2 2 1 AWS domain SRI PF08236.11 GAN08055.1 - 8e-07 29.1 4.4 8.3e-07 29.1 1.7 2.3 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 GAN08055.1 - 9.2e-07 28.8 0.6 4.3e-06 26.7 0.6 2.2 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 GAN08055.1 - 0.0043 17.1 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RteC PF09357.10 GAN08055.1 - 0.0046 16.7 0.2 0.0046 16.7 0.2 2.3 2 0 0 2 2 2 1 RteC protein CAP_N PF01213.19 GAN08055.1 - 0.59 9.6 10.8 1.8 8.0 10.8 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UCH PF00443.29 GAN08057.1 - 1.7e-74 250.6 0.1 2.6e-74 250.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN08057.1 - 3.3e-15 56.5 4.2 7.3e-08 32.4 0.1 3.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PAC1 PF16094.5 GAN08058.1 - 1.4e-13 50.7 0.1 1.6e-13 50.5 0.1 1.3 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 PP-binding PF00550.25 GAN08059.1 - 7.1e-14 51.9 0.1 9.2e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAN08059.1 - 7.8e-05 22.8 0.3 9.1e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 Acyl-carrier SARS_3b PF12383.8 GAN08059.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein DUF383 PF04063.14 GAN08060.1 - 1.6e-63 213.9 0.2 4.6e-63 212.3 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GAN08060.1 - 5e-17 61.5 0.5 1.4e-16 60.0 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) SecE PF00584.20 GAN08061.1 - 9.4e-13 47.9 0.0 1.1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Arf PF00025.21 GAN08062.1 - 1.7e-39 135.0 0.0 1.9e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAN08062.1 - 8.3e-18 64.5 0.0 9.7e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN08062.1 - 8.3e-17 61.5 0.0 1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAN08062.1 - 7.5e-10 38.6 0.0 8.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAN08062.1 - 6.8e-09 35.4 0.0 7.6e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAN08062.1 - 8.1e-09 35.6 0.0 9.9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAN08062.1 - 4.3e-08 32.7 0.7 4.1e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 GAN08062.1 - 0.0072 16.4 0.1 0.3 11.1 0.3 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 GAN08062.1 - 0.021 14.4 0.2 0.069 12.7 0.1 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 GAN08062.1 - 0.096 13.0 0.1 3.9 7.7 0.0 2.0 1 1 0 2 2 2 0 AAA domain cobW PF02492.19 GAN08062.1 - 0.11 12.1 0.0 14 5.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAN08062.1 - 0.15 12.4 0.1 15 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AA_permease_2 PF13520.6 GAN08063.1 - 7.4e-53 179.9 33.2 9.4e-53 179.6 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN08063.1 - 1.4e-19 70.0 30.7 2e-19 69.5 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease ATG11 PF10377.9 GAN08063.1 - 0.21 11.6 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 DUF1129 PF06570.11 GAN08063.1 - 6.5 6.2 14.6 1.2 8.5 1.4 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) Aminotran_4 PF01063.19 GAN08066.1 - 7.1e-25 88.2 0.0 8.4e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DnaJ-X PF14308.6 GAN08067.1 - 7.2e-54 182.4 0.3 7.2e-54 182.4 0.3 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAN08067.1 - 1e-24 86.4 1.1 1.7e-24 85.7 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain Nucleos_tra2_C PF07662.13 GAN08068.1 - 1.9e-71 240.2 2.3 1.9e-71 240.2 2.3 2.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 GAN08068.1 - 7.7e-22 77.7 9.7 8.7e-21 74.3 5.5 3.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus DUF4083 PF13314.6 GAN08068.1 - 1.6 8.7 5.5 0.4 10.7 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF4191 PF13829.6 GAN08068.1 - 4.2 6.7 5.8 0.51 9.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4131 PF13567.6 GAN08068.1 - 8.5 6.0 8.4 0.44 10.2 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Sec2p PF06428.11 GAN08069.1 - 1.4e-17 63.4 13.2 1.4e-17 63.4 13.2 3.2 1 1 2 3 3 3 1 GDP/GTP exchange factor Sec2p ERM PF00769.19 GAN08069.1 - 0.0072 16.2 20.8 0.017 14.9 20.8 1.7 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Laminin_I PF06008.14 GAN08069.1 - 0.022 14.5 18.7 0.041 13.6 18.7 1.4 1 0 0 1 1 1 0 Laminin Domain I DUF790 PF05626.11 GAN08069.1 - 0.025 13.3 7.4 0.038 12.7 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Jnk-SapK_ap_N PF09744.9 GAN08069.1 - 0.3 11.3 29.9 0.11 12.8 18.4 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 GAN08069.1 - 0.53 10.5 29.0 0.038 14.2 18.6 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.11 GAN08069.1 - 1 9.1 18.3 0.044 13.6 2.5 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 GAN08069.1 - 1.5 8.1 11.6 3 7.1 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3847 PF12958.7 GAN08069.1 - 1.9 8.7 23.2 1.1 9.4 0.4 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3847) TMF_TATA_bd PF12325.8 GAN08069.1 - 2.6 8.3 27.2 5.9 7.2 16.6 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 GAN08069.1 - 6.1 6.3 30.7 9.2 5.7 11.3 2.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF745 PF05335.13 GAN08069.1 - 7.3 6.3 18.8 9.1 6.0 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 GAN08069.1 - 7.5 6.7 26.5 54 3.9 24.7 2.5 1 1 1 2 2 2 0 Tropomyosin like NIF PF03031.18 GAN08070.1 - 1.3e-24 86.8 0.1 1.8e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Gal_GalNac_35kD PF17337.2 GAN08070.1 - 0.0041 17.2 0.7 1.5 8.8 0.1 2.5 2 1 0 2 2 2 2 Galactose-inhibitable lectin 35 kDa subunit Nuc_deoxyri_tr3 PF11071.8 GAN08070.1 - 0.0081 16.2 0.1 0.016 15.3 0.0 1.5 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase YtoQ Glyco_tranf_2_3 PF13641.6 GAN08071.1 - 5.9e-27 95.1 0.0 7.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAN08071.1 - 4e-10 39.8 0.0 8.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN08071.1 - 2.5e-06 27.1 0.3 2.9e-05 23.6 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 GAN08071.1 - 0.027 13.1 0.5 0.32 9.6 0.0 2.2 2 1 0 2 2 2 0 Chitin synthase SLIDE PF09111.10 GAN08071.1 - 0.082 12.9 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 SLIDE Peptidase_C1_2 PF03051.15 GAN08072.1 - 1.1e-165 551.7 1.1 1.3e-165 551.4 1.1 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 GAN08072.1 - 9e-05 22.7 1.2 0.17 12.0 0.2 2.9 2 1 1 3 3 3 2 Papain family cysteine protease YflT PF11181.8 GAN08072.1 - 0.073 13.6 0.8 0.16 12.5 0.8 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT Peptidase_M3 PF01432.20 GAN08073.1 - 1.3e-144 482.9 1.2 1.9e-144 482.3 1.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 DSS1_SEM1 PF05160.13 GAN08075.1 - 3.1e-15 56.0 22.1 5.7e-15 55.1 22.1 1.4 1 0 0 1 1 1 1 DSS1/SEM1 family SUR7 PF06687.12 GAN08076.1 - 7.9e-20 71.4 13.2 1.3e-19 70.7 13.2 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF2768 PF10966.8 GAN08076.1 - 0.023 15.1 9.2 0.023 15.1 9.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2768) DUF996 PF06195.13 GAN08076.1 - 4.4 7.6 13.1 0.73 10.1 7.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Cyt-b5 PF00173.28 GAN08077.1 - 1.4e-23 82.8 0.2 1.4e-23 82.8 0.2 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 GAN08077.1 - 5.9e-14 52.6 19.4 5.9e-14 52.6 19.4 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily YqhR PF11085.8 GAN08077.1 - 0.23 11.4 2.8 0.86 9.5 1.1 2.1 2 0 0 2 2 2 0 Conserved membrane protein YqhR ECF_trnsprt PF12822.7 GAN08077.1 - 3.7 7.6 9.0 0.26 11.4 1.6 2.0 1 1 1 2 2 2 0 ECF transporter, substrate-specific component DUF456 PF04306.13 GAN08077.1 - 5 7.4 6.9 18 5.6 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF4448 PF14610.6 GAN08078.1 - 2.3e-06 27.5 2.6 4.4e-06 26.6 0.6 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 GAN08078.1 - 0.0034 16.2 0.0 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2014 PF09427.10 GAN08078.1 - 0.18 11.1 5.2 0.34 10.2 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) SLY PF12485.8 GAN08078.1 - 8.8 7.0 16.1 3.2 8.5 6.4 2.6 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein FAM176 PF14851.6 GAN08078.1 - 9.2 5.9 7.9 3.2 7.4 3.7 2.2 2 0 0 2 2 2 0 FAM176 family MOZ_SAS PF01853.18 GAN08079.1 - 4.8e-84 280.5 0.3 8.3e-84 279.7 0.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAN08079.1 - 3.5e-24 84.2 5.8 8.5e-24 82.9 5.8 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAN08079.1 - 1.9e-20 72.5 0.2 1.3e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 GAN08079.1 - 0.0024 18.2 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN08079.1 - 0.0073 16.5 0.0 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family TFIIE_beta PF02186.15 GAN08079.1 - 0.091 13.1 0.2 4.4 7.7 0.0 2.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain PX PF00787.24 GAN08079.1 - 0.11 12.5 1.3 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 PX domain Sdh_cyt PF01127.22 GAN08080.1 - 4.3e-24 84.9 2.6 6e-24 84.4 2.6 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mito_carr PF00153.27 GAN08082.1 - 8.1e-69 227.6 4.0 1.6e-22 79.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAN08082.1 - 6.8e-07 29.6 0.6 0.00021 21.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN08082.1 - 2.3e-05 24.0 0.1 0.47 10.5 0.1 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 GAN08082.1 - 5e-05 23.1 0.1 0.00071 19.4 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAN08082.1 - 0.053 13.1 0.2 0.87 9.3 0.0 2.7 3 0 0 3 3 3 0 EF hand Serine_protease PF18405.1 GAN08082.1 - 0.056 12.6 0.8 0.93 8.6 0.1 2.8 2 1 2 4 4 4 0 Gammaproteobacterial serine protease ApoO PF09769.9 GAN08083.1 - 5.1e-29 100.9 7.3 5.5e-26 91.0 0.5 2.7 1 1 1 2 2 2 2 Apolipoprotein O Apolipoprotein PF01442.18 GAN08083.1 - 1.6e-07 31.4 2.6 1.6e-07 31.4 2.6 2.4 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 GAN08083.1 - 3.2e-05 24.0 16.8 0.0024 18.0 8.5 2.7 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 GAN08083.1 - 0.00063 17.8 3.2 0.00095 17.3 3.2 1.2 1 0 0 1 1 1 1 Prominin PspA_IM30 PF04012.12 GAN08083.1 - 0.0015 18.2 3.7 0.0015 18.2 3.7 2.0 2 0 0 2 2 2 1 PspA/IM30 family YtxH PF12732.7 GAN08083.1 - 0.003 18.0 13.3 0.047 14.2 3.4 3.5 2 1 1 3 3 3 1 YtxH-like protein Fzo_mitofusin PF04799.13 GAN08083.1 - 0.008 15.7 2.2 0.008 15.7 2.2 2.3 2 1 0 2 2 2 1 fzo-like conserved region Tweety PF04906.13 GAN08083.1 - 0.013 14.2 0.9 0.013 14.2 0.9 1.8 2 0 0 2 2 2 0 Tweety Baculo_PEP_C PF04513.12 GAN08083.1 - 0.013 15.5 3.1 0.061 13.4 0.8 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 GAN08083.1 - 0.018 15.1 11.0 1.6 8.7 0.3 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 GAN08083.1 - 0.022 15.4 3.4 0.022 15.4 3.4 3.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 GAN08083.1 - 0.028 14.5 5.2 0.07 13.2 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RmuC PF02646.16 GAN08083.1 - 0.037 13.2 7.4 0.05 12.7 0.3 2.9 2 1 1 3 3 3 0 RmuC family HisKA_3 PF07730.13 GAN08083.1 - 0.039 14.5 1.8 2.5 8.7 0.8 3.5 2 1 1 3 3 3 0 Histidine kinase PIN_8 PF18476.1 GAN08083.1 - 0.055 13.3 5.6 0.023 14.6 1.4 1.9 2 0 0 2 2 2 0 PIN like domain DUF1759 PF03564.15 GAN08083.1 - 0.06 13.3 2.0 0.07 13.1 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) TMPIT PF07851.13 GAN08083.1 - 0.19 11.0 5.8 0.14 11.4 2.8 1.8 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 GAN08083.1 - 0.19 11.9 10.9 0.2 11.8 5.9 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 GAN08083.1 - 0.2 11.1 1.7 0.14 11.7 0.2 1.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein AI-2E_transport PF01594.16 GAN08083.1 - 0.24 10.5 0.4 1 8.5 0.1 1.9 1 1 1 2 2 2 0 AI-2E family transporter Gp-FAR-1 PF05823.12 GAN08083.1 - 0.25 11.7 5.5 5.2 7.4 1.5 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SKA2 PF16740.5 GAN08083.1 - 0.35 10.7 5.9 0.54 10.1 1.9 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 THP2 PF09432.10 GAN08083.1 - 0.36 10.9 3.3 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Tho complex subunit THP2 DUF1640 PF07798.11 GAN08083.1 - 0.68 10.0 7.7 0.23 11.5 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) TolA_bind_tri PF16331.5 GAN08083.1 - 0.79 9.8 8.3 0.22 11.6 5.0 2.0 2 1 0 2 2 1 0 TolA binding protein trimerisation ParB PF08775.10 GAN08083.1 - 1.1 9.8 7.9 0.25 11.8 3.1 2.1 2 0 0 2 2 2 0 ParB family Muted PF14942.6 GAN08083.1 - 1.1 9.6 6.9 0.46 10.8 1.3 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.11 GAN08083.1 - 1.5 9.1 11.4 3.9 7.8 4.7 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) dCache_2 PF08269.11 GAN08083.1 - 2.8 7.0 11.4 3.5 6.7 2.2 2.3 1 1 0 2 2 2 0 Cache domain CsbD PF05532.12 GAN08083.1 - 3 7.8 5.5 7.8 6.5 0.4 2.6 1 1 0 2 2 2 0 CsbD-like COG2 PF06148.11 GAN08083.1 - 5.9 7.0 8.0 4.6 7.3 4.2 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CH PF00307.31 GAN08084.1 - 3.1e-22 78.8 0.0 4.3e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 GAN08084.1 - 8.2e-06 25.4 4.4 1.4e-05 24.6 4.4 1.4 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 GAN08084.1 - 0.04 13.7 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain PdaC PF13739.6 GAN08084.1 - 0.28 12.2 3.9 4.9 8.2 2.1 2.3 2 1 0 2 2 2 0 Deacetylase PdaC DUF2828 PF11443.8 GAN08085.1 - 0.05 11.7 0.2 0.062 11.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ribosomal_S15 PF00312.22 GAN08085.1 - 0.13 12.5 1.8 0.16 12.2 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein S15 Myb_DNA-binding PF00249.31 GAN08086.1 - 1.1e-13 51.1 1.0 2.5e-13 50.0 0.4 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2 PF00096.26 GAN08086.1 - 1.1e-12 47.6 17.7 0.00034 20.9 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type Myb_DNA-bind_6 PF13921.6 GAN08086.1 - 1.1e-11 44.8 1.5 2.9e-11 43.4 0.7 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 GAN08086.1 - 1.1e-08 35.2 14.6 0.02 15.7 0.4 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN08086.1 - 3.4e-07 30.4 6.0 1.1e-05 25.6 0.5 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAN08086.1 - 3.1e-05 23.9 12.3 0.025 14.6 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger SLIDE PF09111.10 GAN08086.1 - 0.00039 20.4 0.6 0.001 19.1 0.0 2.0 2 0 0 2 2 1 1 SLIDE CHDCT2 PF08074.11 GAN08086.1 - 0.0025 18.0 0.1 0.0025 18.0 0.1 3.2 2 1 1 3 3 2 1 CHDCT2 (NUC038) domain zf-C2H2_8 PF15909.5 GAN08086.1 - 0.015 15.6 4.5 0.071 13.4 2.2 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 GAN08086.1 - 0.034 14.3 0.3 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Aberrant zinc-finger UBA_4 PF14555.6 GAN08086.1 - 0.034 14.0 0.1 0.087 12.7 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain Rap1_C PF11626.8 GAN08086.1 - 0.054 13.6 0.2 0.17 12.0 0.2 1.9 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2HE PF16278.5 GAN08086.1 - 0.065 13.7 7.1 4 7.9 1.4 3.8 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 GAN08086.1 - 0.57 10.3 3.1 3.8 7.7 0.4 2.6 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 GAN08086.1 - 8.5 6.8 11.7 5.4 7.4 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding HTH_28 PF13518.6 GAN08087.1 - 2.7e-07 30.6 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 GAN08087.1 - 0.00013 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 GAN08087.1 - 0.0013 19.2 0.0 0.0018 18.7 0.0 1.2 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_29 PF13551.6 GAN08087.1 - 0.0085 16.1 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_17 PF12728.7 GAN08087.1 - 0.018 15.2 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 GAN08087.1 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposase HLH PF00010.26 GAN08088.1 - 1.1e-13 50.9 0.8 1.1e-13 50.9 0.8 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain AAA_23 PF13476.6 GAN08088.1 - 0.17 12.3 14.4 0.32 11.4 14.4 1.4 1 0 0 1 1 1 0 AAA domain GATA PF00320.27 GAN08089.1 - 6.5e-31 105.6 17.3 7.2e-16 57.5 2.7 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN08089.1 - 6.6e-05 22.3 5.7 0.011 15.2 1.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 GAN08089.1 - 0.00035 20.6 2.5 0.28 11.3 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 GAN08089.1 - 0.00042 20.4 1.6 0.9 9.7 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain TDP43_N PF18694.1 GAN08089.1 - 0.002 17.9 0.1 0.61 10.0 0.0 2.4 2 0 0 2 2 2 2 Transactive response DNA-binding protein N-terminal domain Auto_anti-p27 PF06677.12 GAN08089.1 - 0.014 15.5 5.4 1.2 9.3 0.7 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 GAN08089.1 - 0.016 15.2 4.0 1.9 8.6 0.5 2.9 2 1 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 GAN08089.1 - 0.036 13.9 4.1 3.8 7.4 0.3 2.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Sec2p PF06428.11 GAN08089.1 - 0.1 12.6 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Vps36-NZF-N PF16988.5 GAN08089.1 - 0.1 12.0 3.0 0.69 9.3 0.1 3.3 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SUI1 PF01253.22 GAN08090.1 - 5.4e-22 78.1 0.1 7.1e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 PBP PF01161.20 GAN08091.1 - 5.1e-20 72.1 0.1 6.1e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ras PF00071.22 GAN08092.1 - 2.4e-55 186.5 0.5 2.8e-55 186.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN08092.1 - 4.6e-34 117.2 0.0 6.9e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN08092.1 - 4.8e-13 48.9 0.0 5.7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN08092.1 - 4.7e-06 26.1 0.0 7.5e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN08092.1 - 0.00089 19.3 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN08092.1 - 0.00092 18.8 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAN08092.1 - 0.016 15.6 0.0 0.019 15.3 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAN08092.1 - 0.019 14.9 0.1 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 GAN08092.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LigT_PEase PF02834.16 GAN08092.1 - 0.044 14.0 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 LigT like Phosphoesterase AAA_24 PF13479.6 GAN08092.1 - 0.066 12.9 0.0 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_capsid PF03035.14 GAN08092.1 - 0.094 12.7 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein TniB PF05621.11 GAN08092.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RTA1 PF04479.13 GAN08093.1 - 1.4e-40 139.1 8.0 1.6e-40 138.9 8.0 1.0 1 0 0 1 1 1 1 RTA1 like protein Chitin_synth_2 PF03142.15 GAN08094.1 - 1.9e-226 752.8 2.0 3e-226 752.1 2.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAN08094.1 - 1e-113 381.0 1.8 1.4e-113 380.5 1.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 GAN08094.1 - 2.7e-20 72.3 0.5 1.5e-13 50.7 0.1 3.7 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 GAN08094.1 - 1.9e-15 56.5 0.2 4.9e-15 55.2 0.2 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 GAN08094.1 - 2.2e-10 40.8 2.1 1.8e-09 37.9 0.0 3.0 4 0 0 4 4 4 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN08094.1 - 7.3e-10 39.1 3.8 7.3e-10 39.1 3.8 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 TraO PF10626.9 GAN08094.1 - 0.022 14.5 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Conjugative transposon protein TraO Sel1 PF08238.12 GAN08095.1 - 8.9e-28 96.1 24.1 7.8e-09 35.9 2.2 7.0 6 0 0 6 6 6 6 Sel1 repeat Ras PF00071.22 GAN08096.1 - 2.6e-47 160.4 0.1 2.8e-47 160.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN08096.1 - 7.9e-33 113.2 0.1 1e-32 112.9 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN08096.1 - 6.7e-13 48.5 0.0 7.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN08096.1 - 1.7e-07 31.4 0.0 2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN08096.1 - 1.2e-06 28.0 0.1 1.6e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAN08096.1 - 0.00013 21.6 0.1 0.0054 16.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN08096.1 - 0.00034 20.5 0.1 0.0023 17.9 0.1 2.1 1 1 2 3 3 3 1 RsgA GTPase cobW PF02492.19 GAN08096.1 - 0.00077 19.1 0.0 0.0018 17.9 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAN08096.1 - 0.0044 17.4 0.0 0.0069 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 GAN08096.1 - 0.0057 16.5 0.5 0.17 11.6 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 GAN08096.1 - 0.0095 16.2 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 GAN08096.1 - 0.0097 15.4 0.0 0.011 15.2 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAN08096.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 GAN08096.1 - 0.013 14.8 0.2 0.029 13.7 0.1 1.6 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 GAN08096.1 - 0.015 14.8 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAN08096.1 - 0.035 13.3 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 GAN08096.1 - 0.043 13.6 0.2 0.061 13.1 0.2 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 GAN08096.1 - 0.046 13.6 0.1 0.064 13.2 0.1 1.2 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 GAN08096.1 - 0.054 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 GAN08096.1 - 0.054 13.5 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_hydro_75 PF07335.11 GAN08096.1 - 0.059 13.6 0.0 0.098 12.9 0.0 1.4 1 1 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 ATPase_2 PF01637.18 GAN08096.1 - 0.066 13.1 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 GAN08096.1 - 0.075 12.4 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 GAN08096.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 GAN08096.1 - 0.16 12.5 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 GAN08096.1 - 0.18 12.4 0.1 0.84 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sod_Fe_C PF02777.18 GAN08097.1 - 2.4e-40 136.9 1.0 3e-40 136.5 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAN08097.1 - 2.3e-31 108.1 2.1 4.5e-31 107.1 2.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Alk_phosphatase PF00245.20 GAN08098.1 - 1.2e-96 324.2 0.2 1.4e-96 324.0 0.2 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAN08098.1 - 0.051 12.9 0.1 0.15 11.4 0.1 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily FAE1_CUT1_RppA PF08392.12 GAN08098.1 - 0.073 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein SNARE PF05739.19 GAN08099.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 SNARE domain Phage_CI_repr PF07022.13 GAN08099.1 - 0.052 13.7 0.1 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain APS_kinase PF01583.20 GAN08100.1 - 6.8e-72 240.5 0.0 8.2e-72 240.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 GAN08100.1 - 6.1e-08 32.9 0.0 8.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAN08100.1 - 0.0024 17.4 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 GAN08100.1 - 0.0082 16.7 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAN08100.1 - 0.0089 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GAN08100.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF463 PF04317.12 GAN08100.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 GAN08100.1 - 0.14 12.5 0.1 0.22 11.9 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain CH PF00307.31 GAN08101.1 - 8e-31 106.5 1.0 6.9e-15 55.2 0.0 3.4 2 0 0 2 2 2 2 Calponin homology (CH) domain GAS2 PF02187.17 GAN08101.1 - 7.2e-11 42.0 0.0 4.6e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.8 GAN08101.1 - 0.00029 20.6 0.3 0.0059 16.4 0.0 3.2 2 0 0 2 2 2 1 CAMSAP CH domain Telomere_reg-2 PF10193.9 GAN08101.1 - 1.3 9.5 6.1 11 6.6 0.2 4.7 3 0 0 3 3 3 0 Telomere length regulation protein Methyltransf_11 PF08241.12 GAN08102.1 - 5.4e-18 65.4 0.0 9.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN08102.1 - 9.3e-15 55.1 0.0 2.3e-14 53.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08102.1 - 1.1e-13 51.4 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN08102.1 - 7.7e-09 35.2 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN08102.1 - 4e-08 33.9 0.0 6.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08102.1 - 2.2e-05 24.3 0.2 0.00035 20.4 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAN08102.1 - 2.4e-05 24.3 0.0 3.9e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.20 GAN08102.1 - 0.0005 19.2 0.0 0.00073 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 GAN08102.1 - 0.0013 18.1 0.1 0.0027 17.0 0.1 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 GAN08102.1 - 0.0014 17.2 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_PK PF05891.12 GAN08102.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.4 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 GAN08102.1 - 0.0018 17.5 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_16 PF10294.9 GAN08102.1 - 0.0036 17.1 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAN08102.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 GAN08102.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PyocinActivator PF11112.8 GAN08102.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyocin activator protein PrtN Methyltransf_32 PF13679.6 GAN08102.1 - 0.04 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FHA PF00498.26 GAN08103.1 - 1.4e-18 66.9 0.0 3.4e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Macoilin PF09726.9 GAN08103.1 - 4.8e-07 28.7 12.9 6.7e-07 28.3 12.9 1.1 1 0 0 1 1 1 1 Macoilin family Yop-YscD_cpl PF16697.5 GAN08103.1 - 1.9e-05 24.9 0.0 7.7e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LMBR1 PF04791.16 GAN08103.1 - 0.0039 16.2 0.6 0.0046 15.9 0.6 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 GAN08103.1 - 0.0044 17.1 19.6 0.0083 16.2 17.9 2.1 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 GAN08103.1 - 0.0048 16.6 23.2 0.12 12.0 22.3 2.4 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.12 GAN08103.1 - 0.0094 14.2 20.3 0.19 9.8 20.8 1.9 1 1 1 2 2 2 2 HOOK protein Exonuc_VII_L PF02601.15 GAN08103.1 - 0.014 15.0 10.6 0.024 14.2 10.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C4H2 PF10146.9 GAN08103.1 - 0.046 14.0 13.0 0.11 12.7 13.0 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein EzrA PF06160.12 GAN08103.1 - 0.047 11.9 15.0 0.067 11.4 15.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 GAN08103.1 - 0.068 12.0 16.4 0.14 11.0 16.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.21 GAN08103.1 - 0.1 12.2 17.2 0.29 10.7 17.3 1.6 1 1 0 1 1 1 0 Intermediate filament protein MobL PF18555.1 GAN08103.1 - 0.12 11.5 11.7 0.27 10.4 11.7 1.5 1 0 0 1 1 1 0 MobL relaxases Cob_adeno_trans PF01923.18 GAN08103.1 - 0.27 11.4 6.8 0.22 11.6 3.6 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Fez1 PF06818.15 GAN08103.1 - 0.42 11.0 16.7 0.25 11.8 10.7 2.3 1 1 1 2 2 2 0 Fez1 Bcr-Abl_Oligo PF09036.10 GAN08103.1 - 0.56 10.2 7.2 0.36 10.9 0.6 2.6 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Golgin_A5 PF09787.9 GAN08103.1 - 0.57 9.6 18.8 1.6 8.1 18.8 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 GAN08103.1 - 0.62 7.9 8.1 0.89 7.4 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2564 PF10819.8 GAN08103.1 - 0.73 10.3 9.3 4.5 7.7 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) ATG16 PF08614.11 GAN08103.1 - 1 9.5 19.8 0.16 12.2 12.0 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TRAF_BIRC3_bd PF16673.5 GAN08103.1 - 1.3 8.8 7.4 3.7 7.4 2.6 2.9 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain FlaC_arch PF05377.11 GAN08103.1 - 1.4 9.3 11.2 3.7 8.0 1.5 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 GAN08103.1 - 1.5 9.5 16.5 5.8 7.6 5.4 3.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 WXG100 PF06013.12 GAN08103.1 - 2.4 8.4 11.0 7.5 6.9 4.9 3.0 1 1 2 3 3 3 0 Proteins of 100 residues with WXG YgaB PF14182.6 GAN08103.1 - 2.5 8.6 10.0 0.16 12.4 2.8 2.5 1 1 1 2 2 1 0 YgaB-like protein DUF1664 PF07889.12 GAN08103.1 - 2.7 8.0 10.0 7.4 6.6 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 GAN08103.1 - 3.2 5.4 12.3 8.6 4.0 12.3 1.6 1 1 0 1 1 1 0 Nuclear pore component BLOC1_2 PF10046.9 GAN08103.1 - 3.7 7.9 12.2 2.9 8.2 0.8 2.8 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 GAN08103.1 - 3.7 6.8 16.3 7.2 5.9 14.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 GAN08103.1 - 5.3 7.3 17.6 3.6 7.8 6.3 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KxDL PF10241.9 GAN08103.1 - 5.9 7.3 12.9 5.4 7.4 0.7 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein FAM76 PF16046.5 GAN08103.1 - 6.7 6.0 13.9 12 5.1 13.9 1.3 1 0 0 1 1 1 0 FAM76 protein Argos PF11581.8 GAN08106.1 - 0.022 14.8 1.4 0.031 14.3 1.4 1.3 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Pro_isomerase PF00160.21 GAN08107.1 - 4.2e-42 144.1 0.1 1.2e-41 142.6 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.23 GAN08108.1 - 7.8e-19 67.2 0.2 1.3e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAN08108.1 - 0.00033 21.2 0.0 0.00033 21.2 0.0 3.1 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 GAN08108.1 - 0.0009 19.0 0.5 0.0026 17.6 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 GAN08108.1 - 0.0097 16.0 0.0 0.042 13.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GAN08108.1 - 0.029 14.4 0.6 0.16 12.0 0.6 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 GAN08108.1 - 0.15 12.4 0.8 0.34 11.3 0.2 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Coilin_N PF15862.5 GAN08108.1 - 9.3 6.1 10.7 31 4.4 7.7 2.5 2 0 0 2 2 2 0 Coilin N-terminus EPOP PF15223.6 GAN08109.1 - 0.06 12.7 9.2 0.11 11.8 9.2 1.4 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein SEEEED PF14797.6 GAN08109.1 - 4.9 7.3 26.8 23 5.2 26.7 2.2 1 1 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex APH PF01636.23 GAN08110.1 - 8.1e-45 153.6 0.0 1.1e-44 153.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAN08110.1 - 1.9e-05 24.1 0.0 3.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 GAN08110.1 - 0.0019 17.5 0.0 0.15 11.2 0.0 2.4 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 GAN08110.1 - 0.0082 15.8 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 GAN08110.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 GAN08110.1 - 0.21 10.4 0.2 1.1 8.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) CGI-121 PF08617.10 GAN08111.1 - 2e-40 138.6 1.1 2.3e-40 138.4 1.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 2-ph_phosp PF04029.14 GAN08111.1 - 0.038 13.1 0.2 0.056 12.6 0.2 1.3 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase zf-C2H2 PF00096.26 GAN08112.1 - 6e-06 26.4 3.3 1.2e-05 25.4 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN08112.1 - 0.036 14.9 1.9 0.086 13.7 1.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF448 PF04296.13 GAN08112.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF448) Tubulin PF00091.25 GAN08113.1 - 1.4e-66 224.5 0.0 1.9e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAN08113.1 - 6.8e-51 171.7 0.0 1e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAN08113.1 - 0.00054 19.7 0.0 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain HLH PF00010.26 GAN08114.1 - 2.3e-17 62.7 2.5 5.1e-17 61.6 2.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HgmA PF04209.13 GAN08115.1 - 1.2e-210 699.6 0.2 1.4e-210 699.4 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PEX11 PF05648.14 GAN08116.1 - 1.4 8.3 3.4 0.89 9.0 0.1 2.0 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Lipase_GDSL PF00657.22 GAN08117.1 - 2.7e-11 43.8 0.1 4.2e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN08117.1 - 0.0021 18.5 0.0 0.48 10.8 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family RasGEF PF00617.19 GAN08118.1 - 2.8e-40 138.4 0.0 6.6e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain BUD22 PF09073.10 GAN08118.1 - 0.00069 19.1 6.5 0.00069 19.1 6.5 2.6 2 1 0 2 2 2 1 BUD22 DUF4611 PF15387.6 GAN08118.1 - 0.53 10.5 22.7 0.58 10.4 3.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GAN08118.1 - 5.8 6.2 27.5 0.066 12.5 15.0 2.2 2 0 0 2 2 2 0 NOA36 protein HNF-1_N PF04814.13 GAN08118.1 - 5.9 7.5 13.1 1.1 9.8 7.3 2.5 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Cwf_Cwc_15 PF04889.12 GAN08118.1 - 8.7 6.0 27.4 0.071 12.8 10.5 2.7 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein TAFII28 PF04719.14 GAN08119.1 - 9.5e-35 118.6 1.0 1.2e-34 118.2 0.1 1.7 2 0 0 2 2 2 1 hTAFII28-like protein conserved region MSP1_C PF07462.11 GAN08119.1 - 0.024 13.3 5.4 0.032 13.0 5.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4407 PF14362.6 GAN08119.1 - 1.5 8.1 7.0 2 7.7 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPP4R2 PF09184.11 GAN08119.1 - 5 6.6 12.4 6.6 6.2 12.4 1.2 1 0 0 1 1 1 0 PPP4R2 Neurochondrin PF05536.11 GAN08121.1 - 2.7e-53 181.3 11.2 3.1e-53 181.1 11.2 1.0 1 0 0 1 1 1 1 Neurochondrin DUF4018 PF13210.6 GAN08121.1 - 0.011 15.6 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) SLED PF12140.8 GAN08121.1 - 0.043 14.3 0.4 0.23 12.0 0.1 2.3 2 0 0 2 2 2 0 SLED domain Utp12 PF04003.12 GAN08121.1 - 0.075 13.3 8.4 1.5 9.2 0.0 3.6 4 0 0 4 4 4 0 Dip2/Utp12 Family DUF2937 PF11157.8 GAN08121.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MOR2-PAG1_C PF14225.6 GAN08121.1 - 4.4 7.1 12.4 0.36 10.6 2.7 3.6 2 2 1 4 4 4 0 Cell morphogenesis C-terminal zf-CCCH PF00642.24 GAN08122.1 - 2.2e-19 68.9 16.3 2.4e-10 40.1 2.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) W2 PF02020.18 GAN08122.1 - 4.9e-10 39.4 5.2 4.9e-10 39.4 5.2 3.1 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon zf_CCCH_4 PF18345.1 GAN08122.1 - 3e-08 33.4 14.0 0.00012 22.0 1.1 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAN08122.1 - 4.9e-07 29.4 14.0 0.00047 19.9 2.0 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger NUDIX PF00293.28 GAN08122.1 - 3.3e-06 27.2 0.0 1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain zf-CCCH_2 PF14608.6 GAN08122.1 - 9.2e-05 22.8 14.0 0.028 14.9 4.9 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger TPR_1 PF00515.28 GAN08123.1 - 5.9e-24 82.9 11.0 7.5e-11 41.4 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 GAN08123.1 - 1.1e-23 82.7 0.4 2.6e-23 81.6 0.4 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 GAN08123.1 - 1.2e-19 68.8 10.0 2.2e-08 33.6 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN08123.1 - 3.4e-18 65.0 13.7 6.9e-07 28.8 0.5 3.3 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.6 GAN08123.1 - 2.4e-14 52.6 5.7 8.3e-06 25.8 1.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAN08123.1 - 4.5e-14 51.3 2.5 8e-06 25.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN08123.1 - 1.5e-13 49.8 12.9 6.8e-06 25.9 0.3 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN08123.1 - 1.5e-11 44.4 4.7 1.5e-06 28.4 1.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAN08123.1 - 1.1e-10 41.4 3.0 0.0022 18.7 0.0 4.0 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAN08123.1 - 2.4e-10 40.9 2.8 1e-05 26.1 2.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAN08123.1 - 2.8e-09 36.5 5.6 0.00068 19.4 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN08123.1 - 3.1e-09 37.2 6.3 3.3e-06 27.5 0.1 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN08123.1 - 4.8e-05 22.7 2.4 0.00068 18.9 1.5 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN08123.1 - 7.7e-05 22.8 5.0 0.00014 22.0 5.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GAN08123.1 - 0.00018 21.6 0.8 0.0079 16.3 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 GAN08123.1 - 0.00053 20.4 1.2 0.0026 18.2 1.2 2.1 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 GAN08123.1 - 0.015 15.9 5.0 2.5 8.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN08123.1 - 0.044 13.1 1.4 0.051 13.0 0.1 1.8 3 0 0 3 3 3 0 MalT-like TPR region STI1 PF17830.1 GAN08123.1 - 0.049 13.6 12.4 0.58 10.1 0.2 2.6 2 0 0 2 2 2 0 STI1 domain TPR_4 PF07721.14 GAN08123.1 - 0.12 13.1 0.0 0.59 10.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 GAN08123.1 - 0.25 11.4 0.1 0.25 11.4 0.1 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3391 PF11871.8 GAN08123.1 - 0.59 10.7 4.6 1 9.9 4.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) NmrA PF05368.13 GAN08124.1 - 6e-08 32.5 0.0 2.6e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAN08124.1 - 0.032 14.1 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_1 PF00175.21 GAN08125.1 - 1.3e-32 112.7 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAN08125.1 - 1.4e-22 79.9 0.0 8.9e-22 77.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAN08125.1 - 4.8e-09 36.5 0.0 5.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAN08125.1 - 0.031 14.5 0.1 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Velvet PF11754.8 GAN08126.1 - 1e-30 107.5 12.9 1.1e-15 58.2 0.1 4.2 2 2 2 4 4 4 3 Velvet factor SRF-TF PF00319.18 GAN08127.1 - 3.3e-21 74.5 0.1 5.2e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MFS_1 PF07690.16 GAN08128.1 - 6.9e-35 120.6 62.1 3.3e-25 88.8 41.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN08128.1 - 1e-07 31.2 7.6 1e-07 31.2 7.6 3.5 2 2 1 3 3 3 3 Sugar (and other) transporter DUF4179 PF13786.6 GAN08128.1 - 0.43 11.1 2.1 7.7 7.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) OATP PF03137.20 GAN08128.1 - 0.91 7.7 19.6 0.59 8.3 4.9 4.2 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Ank_2 PF12796.7 GAN08129.1 - 1.4e-59 198.7 11.2 9.6e-16 58.2 0.7 6.4 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN08129.1 - 6.2e-56 186.1 5.5 1.5e-13 51.0 0.1 7.6 4 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN08129.1 - 5.6e-49 163.6 14.4 2e-09 37.5 0.1 7.8 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN08129.1 - 6.9e-46 148.9 0.3 6.3e-06 26.2 0.1 10.5 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 GAN08129.1 - 7.6e-46 152.6 17.2 1e-07 32.1 0.2 9.8 9 0 0 9 9 9 9 Ankyrin repeat Ribosomal_L6 PF00347.23 GAN08130.1 - 4.1e-22 78.7 0.1 7.3e-10 39.4 0.1 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 Methyltransf_32 PF13679.6 GAN08131.1 - 1.5e-29 103.0 0.0 2.5e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08131.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08131.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN08131.1 - 0.006 17.2 0.0 0.049 14.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN08131.1 - 0.015 16.0 0.0 0.088 13.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 GAN08131.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 GAN08131.1 - 0.099 11.9 0.1 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Nuc_deoxyri_tr3 PF11071.8 GAN08132.1 - 0.027 14.5 0.0 0.035 14.2 0.0 1.3 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Aminotran_1_2 PF00155.21 GAN08133.1 - 5.8e-59 200.1 0.0 7e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAN08133.1 - 0.0038 16.6 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 GAN08133.1 - 0.0061 15.3 0.0 0.013 14.3 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Ins134_P3_kin PF05770.11 GAN08133.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ten1_2 PF15490.6 GAN08134.1 - 8.1e-18 64.3 0.3 9.7e-18 64.0 0.3 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Ten1 PF12658.7 GAN08134.1 - 0.00027 20.9 0.3 0.0016 18.4 0.3 1.8 1 1 0 1 1 1 1 Telomere capping, CST complex subunit Rep_fac-A_3 PF08661.11 GAN08134.1 - 0.0081 16.5 0.3 0.0093 16.3 0.3 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-codon PF01336.25 GAN08134.1 - 0.013 15.5 0.0 0.75 9.8 0.0 2.2 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain CTP_transf_like PF01467.26 GAN08135.1 - 3.8e-21 75.8 0.0 4.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Methyltransf_11 PF08241.12 GAN08137.1 - 4e-11 43.4 0.0 8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN08137.1 - 2e-10 41.2 0.0 9.1e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08137.1 - 4.2e-08 33.2 0.0 5.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08137.1 - 7e-08 32.4 0.0 2.9e-07 30.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN08137.1 - 4.8e-05 22.8 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAN08137.1 - 0.00091 19.1 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 GAN08137.1 - 0.0099 16.6 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAN08137.1 - 0.026 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.16 GAN08137.1 - 0.068 11.7 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RabGAP-TBC PF00566.18 GAN08138.1 - 1.5e-18 67.2 3.5 1.2e-10 41.5 0.1 3.0 2 1 1 3 3 3 2 Rab-GTPase-TBC domain DASH_Dad3 PF08656.10 GAN08138.1 - 0.084 13.0 0.0 0.35 11.0 0.0 2.1 1 0 0 1 1 1 0 DASH complex subunit Dad3 MS_channel PF00924.18 GAN08140.1 - 3.4e-19 69.2 0.4 5.9e-19 68.4 0.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 GAN08140.1 - 4.1e-05 22.8 0.1 0.00011 21.5 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAN08140.1 - 7.4e-05 22.4 0.1 0.00021 20.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain DUF2207 PF09972.9 GAN08140.1 - 0.0014 17.5 0.0 0.35 9.6 0.0 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) EF-hand_5 PF13202.6 GAN08140.1 - 0.002 17.6 0.2 0.0054 16.2 0.2 1.7 1 0 0 1 1 1 1 EF hand Ferlin_C PF16165.5 GAN08140.1 - 0.0054 16.7 0.0 0.0054 16.7 0.0 2.0 3 0 0 3 3 3 1 Ferlin C-terminus EF-hand_7 PF13499.6 GAN08140.1 - 0.0091 16.4 0.1 0.028 14.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair Claudin_2 PF13903.6 GAN08140.1 - 0.011 15.5 9.0 0.38 10.5 2.0 3.5 2 1 2 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction ATP_synt_H PF05493.13 GAN08140.1 - 0.014 15.8 6.6 0.014 15.8 6.6 2.4 2 1 0 2 2 2 0 ATP synthase subunit H Colicin_im PF03857.13 GAN08140.1 - 0.76 9.7 3.2 0.25 11.3 0.4 1.6 2 0 0 2 2 2 0 Colicin immunity protein FA_hydroxylase PF04116.13 GAN08142.1 - 1.2e-24 87.2 9.3 1.2e-24 87.2 9.3 2.5 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Ribosomal_60s PF00428.19 GAN08142.1 - 5.9e-24 84.5 5.8 1e-23 83.7 5.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein BIR PF00653.21 GAN08143.1 - 1.9e-29 102.1 3.5 6e-17 62.1 0.6 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain LsmAD PF06741.13 GAN08144.1 - 6.9e-27 93.8 0.1 6.9e-27 93.8 0.1 3.0 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 GAN08144.1 - 1e-17 64.0 0.0 3.6e-17 62.3 0.0 2.0 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribosomal_L11_N PF03946.14 GAN08145.1 - 4e-24 84.2 0.1 8.5e-24 83.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GAN08145.1 - 3.6e-16 59.4 0.1 6.4e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain G_glu_transpept PF01019.21 GAN08146.1 - 2.6e-172 574.2 0.0 3e-172 574.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.18 GAN08146.1 - 0.00067 18.8 0.1 0.2 10.7 0.2 2.2 2 0 0 2 2 2 2 Asparaginase Iso_dh PF00180.20 GAN08147.1 - 3.9e-98 328.8 0.0 1.2e-97 327.2 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase G-gamma PF00631.22 GAN08148.1 - 1.6e-16 60.1 0.0 1.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 GGL domain ERCC4 PF02732.15 GAN08149.1 - 9e-22 77.9 0.0 2.5e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain Csm1_B PF18211.1 GAN08149.1 - 0.27 11.1 1.6 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Csm1 subunit domain B Arm PF00514.23 GAN08150.1 - 1.9e-83 272.2 16.6 3.8e-12 45.8 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 GAN08150.1 - 1.5e-22 78.9 1.8 1.5e-22 78.9 1.8 2.2 3 0 0 3 3 3 1 Atypical Arm repeat IBB PF01749.20 GAN08150.1 - 5.7e-21 74.8 6.0 5.7e-21 74.8 6.0 1.8 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 GAN08150.1 - 9.4e-20 70.7 0.4 2.2e-06 28.0 0.0 5.7 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 GAN08150.1 - 3.9e-16 59.2 0.0 6e-05 23.3 0.0 6.2 2 1 5 7 7 7 4 HEAT repeats HEAT PF02985.22 GAN08150.1 - 1.6e-13 49.7 0.3 0.0011 19.0 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 GAN08150.1 - 5.4e-06 26.0 0.1 1 8.7 0.0 4.2 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 GAN08150.1 - 1.6e-05 25.0 0.0 0.29 11.2 0.0 4.2 3 3 1 4 4 4 3 V-ATPase subunit H RICTOR_V PF14668.6 GAN08150.1 - 0.051 13.8 3.3 5.5 7.3 0.2 3.8 2 2 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 GAN08150.1 - 0.058 14.1 0.5 14 6.7 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Complex1_LYR_2 PF13233.6 GAN08151.1 - 2.3e-11 44.3 1.0 7e-11 42.7 1.0 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAN08151.1 - 1.5e-07 31.4 0.1 2.4e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DDHD PF02862.17 GAN08152.1 - 2.1e-47 162.1 0.0 2.1e-47 162.1 0.0 3.3 3 1 0 3 3 3 1 DDHD domain WWE PF02825.20 GAN08152.1 - 3.9e-05 24.2 0.2 0.13 12.8 0.0 3.3 1 1 1 2 2 2 2 WWE domain CBFB_NFYA PF02045.15 GAN08153.1 - 4.1e-30 104.2 5.2 4.1e-30 104.2 5.2 2.1 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ATP11 PF06644.11 GAN08153.1 - 0.095 12.5 6.4 0.18 11.6 6.4 1.4 1 0 0 1 1 1 0 ATP11 protein Roughex PF06020.11 GAN08153.1 - 0.2 10.7 3.7 0.28 10.2 3.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein ERF PF04404.12 GAN08153.1 - 1.6 8.6 7.5 2.8 7.8 7.5 1.4 1 0 0 1 1 1 0 ERF superfamily Presenilin PF01080.17 GAN08153.1 - 2.5 6.8 4.2 2.6 6.7 4.2 1.2 1 0 0 1 1 1 0 Presenilin SAE2 PF08573.10 GAN08153.1 - 9.7 7.4 13.0 2.5 9.3 1.4 2.3 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Nucleos_tra2_C PF07662.13 GAN08154.1 - 3e-69 233.0 7.3 3e-69 233.0 7.3 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 GAN08154.1 - 3.7e-24 85.1 4.5 3.7e-24 85.1 4.5 2.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus DUF4131 PF13567.6 GAN08154.1 - 5.8 6.5 9.1 84 2.8 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Sec2p PF06428.11 GAN08155.1 - 1.2e-18 66.9 13.5 1.2e-18 66.9 13.5 3.0 3 0 0 3 3 2 1 GDP/GTP exchange factor Sec2p DUF1664 PF07889.12 GAN08155.1 - 3.7e-05 23.8 10.1 5.9e-05 23.1 1.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Filament PF00038.21 GAN08155.1 - 0.00099 18.8 9.7 0.00099 18.8 9.7 2.8 1 1 1 2 2 2 1 Intermediate filament protein DUF4007 PF13182.6 GAN08155.1 - 0.0044 16.2 8.1 0.0056 15.8 6.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF4007) TACC_C PF05010.14 GAN08155.1 - 0.0072 16.1 5.9 0.0072 16.1 5.9 2.7 2 1 0 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TPR_MLP1_2 PF07926.12 GAN08155.1 - 0.018 15.1 13.0 0.018 15.1 13.0 2.9 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF836 PF05768.14 GAN08155.1 - 0.031 14.7 1.4 0.081 13.3 0.8 2.2 2 0 0 2 2 1 0 Glutaredoxin-like domain (DUF836) HALZ PF02183.18 GAN08155.1 - 0.039 14.2 18.9 0.31 11.3 0.8 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper FliD_N PF02465.18 GAN08155.1 - 0.17 12.6 27.1 1.4 9.7 4.9 3.5 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus PLATZ PF04640.14 GAN08155.1 - 0.26 11.9 3.0 17 6.1 1.6 3.1 2 0 0 2 2 2 0 PLATZ transcription factor DUF3446 PF11928.8 GAN08155.1 - 1.6 9.1 12.5 3.7 7.9 8.5 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain CENP-F_leu_zip PF10473.9 GAN08155.1 - 3.9 7.5 29.1 2.2 8.3 10.9 2.9 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3037 PF11236.8 GAN08155.1 - 4.1 7.8 7.1 2.9 8.3 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DUF745 PF05335.13 GAN08155.1 - 5.2 6.7 21.0 0.087 12.5 2.3 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF745) DUF4140 PF13600.6 GAN08155.1 - 5.8 7.4 13.2 30 5.1 1.9 3.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nas2_N PF18265.1 GAN08155.1 - 6.6 6.7 9.1 1.8 8.5 0.9 3.3 3 1 0 3 3 3 0 Nas2 N_terminal domain AATF-Che1 PF13339.6 GAN08155.1 - 6.8 7.4 25.5 0.083 13.6 7.2 3.8 2 2 0 2 2 1 0 Apoptosis antagonizing transcription factor KxDL PF10241.9 GAN08155.1 - 7.4 6.9 19.1 8.9 6.7 8.5 3.6 2 1 0 2 2 2 0 Uncharacterized conserved protein GreA_GreB_N PF03449.15 GAN08155.1 - 9.4 6.5 10.1 6.6 7.0 0.2 3.6 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal THOC7 PF05615.13 GAN08155.1 - 9.4 6.5 23.4 0.35 11.1 6.7 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 NIF PF03031.18 GAN08156.1 - 1.4e-27 96.4 0.8 1.4e-27 96.4 0.8 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Neur_chan_memb PF02932.16 GAN08156.1 - 7.2 6.6 7.8 12 5.9 7.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 GAN08157.1 - 1.2e-63 214.9 0.0 1.5e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08157.1 - 1e-20 74.1 0.0 2.7e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN08157.1 - 0.0001 22.4 0.4 0.043 13.7 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN08157.1 - 0.00022 20.6 0.0 0.049 12.9 0.0 2.2 1 1 0 2 2 2 2 Kinase-like DUF1679 PF07914.11 GAN08157.1 - 0.094 11.6 0.7 0.15 10.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SpvB PF03534.13 GAN08157.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.3 1 1 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein GDA1_CD39 PF01150.17 GAN08158.1 - 4.9e-106 354.9 0.0 6.3e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 GAN08158.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GD_N PF16030.5 GAN08158.1 - 0.04 14.2 0.1 0.077 13.3 0.1 1.4 1 0 0 1 1 1 0 Serine protease gd N-terminus Prenyltransf PF01255.19 GAN08159.1 - 3e-75 252.6 0.0 3.6e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1833 PF08875.11 GAN08159.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Fungal_trans PF04082.18 GAN08160.1 - 3e-07 29.8 1.7 5.3e-07 28.9 0.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abi_2 PF07751.11 GAN08160.1 - 0.056 13.7 1.6 0.24 11.7 0.1 2.9 4 0 0 4 4 4 0 Abi-like protein Cas_Csy4 PF09618.10 GAN08163.1 - 0.06 13.5 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Kinesin PF00225.23 GAN08165.1 - 1.3e-98 330.0 1.0 1.3e-98 330.0 1.0 2.6 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN08165.1 - 3.1e-21 75.9 2.9 4e-21 75.5 0.1 2.8 2 0 0 2 2 2 1 Microtubule binding DUF573 PF04504.14 GAN08165.1 - 0.0086 16.7 2.6 0.0086 16.7 2.6 4.9 2 2 3 5 5 5 1 Protein of unknown function, DUF573 LPP PF04728.13 GAN08165.1 - 0.39 11.1 16.3 48 4.5 0.0 6.6 4 1 0 4 4 4 0 Lipoprotein leucine-zipper AAA_22 PF13401.6 GAN08165.1 - 3.7 7.8 0.0 3.7 7.8 0.0 4.8 5 0 0 5 5 5 0 AAA domain Aldedh PF00171.22 GAN08167.1 - 9e-17 60.7 7.9 1.8e-12 46.6 4.4 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Cu-oxidase_3 PF07732.15 GAN08168.1 - 1.8e-27 95.7 0.5 1.8e-27 95.7 0.5 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 GAN08168.1 - 6.2e-27 94.7 0.1 6.4e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAN08168.1 - 1e-11 44.7 5.0 2.9e-09 36.8 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Mito_carr PF00153.27 GAN08169.1 - 1.6e-60 201.0 11.9 8.1e-21 73.8 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAN08169.1 - 1.8e-19 70.0 3.6 1.2e-10 41.7 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN08169.1 - 2.8e-16 58.0 5.0 0.00056 19.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 GAN08169.1 - 4.2e-16 57.2 4.2 1.1e-05 24.6 1.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAN08169.1 - 1.1e-15 57.2 5.0 2.7e-09 36.8 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 GAN08169.1 - 7.1e-08 31.6 2.7 0.002 17.6 0.7 3.5 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 GAN08169.1 - 9.1e-08 31.9 0.9 0.0046 16.8 0.0 4.0 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 GAN08169.1 - 2.8e-05 24.4 0.1 0.28 11.5 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAN08169.1 - 0.0086 16.0 0.2 1 9.3 0.0 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Cellulase PF00150.18 GAN08170.1 - 3.3e-14 53.0 1.3 5.2e-14 52.3 1.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 GAN08171.1 - 3.8e-52 177.3 0.0 5.4e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08171.1 - 1.8e-24 86.5 0.0 2.7e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAN08171.1 - 4.3e-06 26.5 0.4 0.073 12.7 0.1 2.9 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAN08171.1 - 0.00025 21.1 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN08171.1 - 0.07 12.1 0.1 0.07 12.1 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 GAN08171.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WGR PF05406.15 GAN08171.1 - 0.12 12.4 3.0 0.14 12.2 1.7 1.8 2 0 0 2 2 2 0 WGR domain SR-25 PF10500.9 GAN08171.1 - 1 8.9 6.5 2.2 7.8 6.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 GAN08171.1 - 2.7 7.8 6.0 0.81 9.5 2.7 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family tRNA_Me_trans PF03054.16 GAN08172.1 - 1.6e-116 389.0 0.0 1.9e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 GAN08172.1 - 1.7e-05 24.5 0.0 0.00091 18.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 GAN08172.1 - 1.7e-05 24.1 0.0 9.4e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 GAN08172.1 - 0.0056 16.2 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 GAN08172.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 GAN08172.1 - 0.034 13.8 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DAO PF01266.24 GAN08172.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN08173.1 - 1.9e-48 165.2 0.2 2.2e-48 165.0 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN08173.1 - 4.4e-17 62.3 0.6 3.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN08173.1 - 1.4e-16 60.8 0.4 1.2e-14 54.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAN08173.1 - 0.00025 20.3 0.2 0.18 10.9 0.0 2.8 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN08173.1 - 0.0004 20.6 0.1 0.022 15.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAN08173.1 - 0.00042 19.5 2.5 0.13 11.3 0.0 3.9 4 1 1 5 5 5 1 Glucose inhibited division protein A Thi4 PF01946.17 GAN08173.1 - 0.0053 16.0 0.0 0.038 13.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 GAN08173.1 - 0.0084 16.5 0.0 0.11 12.9 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 GAN08173.1 - 0.01 15.3 0.4 1.6 8.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAN08173.1 - 0.063 12.3 3.7 0.57 9.2 0.2 2.5 2 1 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 GAN08173.1 - 0.075 13.1 0.0 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 GAN08173.1 - 0.084 11.7 0.1 0.84 8.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 GAN08173.1 - 0.093 12.3 1.3 7.9 6.0 0.0 3.1 3 1 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAN08173.1 - 0.1 11.2 0.7 0.5 9.0 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein PNMA PF14893.6 GAN08174.1 - 0.0075 15.7 0.5 0.0085 15.5 0.5 1.0 1 0 0 1 1 1 1 PNMA Complex1_LYR PF05347.15 GAN08174.1 - 0.073 13.1 0.5 0.33 11.0 0.5 2.0 1 1 0 1 1 1 0 Complex 1 protein (LYR family) UDPG_MGDP_dh_N PF03721.14 GAN08175.1 - 0.18 11.4 0.2 0.25 10.9 0.2 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AMPK1_CBM PF16561.5 GAN08176.1 - 9.1e-21 73.9 1.7 1.7e-20 73.0 1.7 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 GAN08176.1 - 0.00086 19.6 0.6 0.003 17.9 0.3 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Rad1 PF02144.16 GAN08176.1 - 0.0024 17.0 5.4 0.046 12.8 5.2 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rhodanese PF00581.20 GAN08177.1 - 6e-13 49.2 0.2 2.3e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Lactamase_B PF00753.27 GAN08177.1 - 2.3e-12 47.3 0.4 2.9e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN08177.1 - 0.00014 21.4 0.1 0.00045 19.8 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PCI PF01399.27 GAN08178.1 - 2.5e-19 69.8 4.8 3.3e-19 69.3 0.4 2.6 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 GAN08178.1 - 9.9e-18 64.0 8.8 3e-17 62.4 8.8 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Symplekin_C PF12295.8 GAN08178.1 - 0.36 10.9 7.6 0.21 11.7 0.3 3.3 1 1 3 4 4 4 0 Symplekin tight junction protein C terminal AMP-binding PF00501.28 GAN08179.1 - 4.6e-92 308.8 0.0 5.7e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN08179.1 - 3.9e-08 34.2 0.0 8.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3570 PF12094.8 GAN08180.1 - 0.14 10.9 0.2 0.17 10.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) Exo_endo_phos PF03372.23 GAN08181.1 - 1.5e-20 73.7 1.8 5.1e-11 42.5 0.1 2.5 3 0 0 3 3 3 2 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 GAN08181.1 - 6.3e-10 38.7 30.1 3e-05 23.7 8.2 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAN08181.1 - 1.4e-09 38.1 19.0 3.9e-07 30.3 2.3 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAN08181.1 - 0.078 12.5 1.2 0.15 11.5 1.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 GAN08181.1 - 0.26 12.0 9.5 4.1 8.3 0.2 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Peptidase_S64 PF08192.11 GAN08181.1 - 0.32 9.4 10.0 0.49 8.8 10.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 GAN08181.1 - 0.82 9.6 19.9 1.2 9.0 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DFP PF04127.15 GAN08182.1 - 6.1e-19 68.6 0.0 8.8e-11 42.0 0.0 2.2 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Peptidase_M9_N PF08453.10 GAN08182.1 - 0.093 12.4 0.6 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Peptidase family M9 N-terminal Ku_PK_bind PF08785.11 GAN08184.1 - 3.9e-26 91.5 1.8 3.9e-26 91.5 1.8 2.1 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.16 GAN08184.1 - 2.2e-25 89.6 0.0 4.2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAN08184.1 - 9.5e-16 58.2 0.2 4.8e-15 55.9 0.2 2.1 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.6 GAN08184.1 - 0.0015 19.1 1.2 0.0086 16.7 0.6 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain Ku_C PF03730.14 GAN08184.1 - 0.0017 19.0 0.0 0.0082 16.8 0.0 2.2 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Serine_protease PF18405.1 GAN08184.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial serine protease A_deaminase PF00962.22 GAN08185.1 - 6.7e-124 413.5 0.1 8.8e-124 413.1 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Syntaxin PF00804.25 GAN08186.1 - 1.8e-37 129.0 18.7 1.8e-37 129.0 18.7 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 GAN08186.1 - 4.7e-06 26.5 0.2 4.7e-06 26.5 0.2 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 GAN08186.1 - 8e-05 23.0 9.0 8e-05 23.0 9.0 3.4 3 1 1 4 4 4 1 Syntaxin-like protein DUF4094 PF13334.6 GAN08186.1 - 0.03 14.7 1.0 0.03 14.7 1.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF4988 PF16378.5 GAN08186.1 - 0.062 13.0 7.0 1.9 8.1 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function PP_kinase_C_1 PF17941.1 GAN08186.1 - 0.096 12.2 2.2 0.1 12.1 0.2 2.1 2 1 1 3 3 3 0 Polyphosphate kinase C-terminal domain 1 FUSC PF04632.12 GAN08186.1 - 0.8 8.2 2.1 1.1 7.7 2.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family GrpE PF01025.19 GAN08186.1 - 3.6 7.2 17.4 28 4.3 14.1 3.0 1 1 1 2 2 2 0 GrpE LPP PF04728.13 GAN08186.1 - 5.3 7.5 9.2 3.9 7.9 1.6 4.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF3290 PF11694.8 GAN08187.1 - 0.069 13.1 1.3 0.072 13.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) ubiquitin PF00240.23 GAN08188.1 - 4.5e-07 29.5 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAN08188.1 - 0.023 15.1 0.4 0.09 13.2 0.2 2.0 2 1 0 2 2 2 0 Ubiquitin-like domain F-box-like PF12937.7 GAN08189.1 - 2e-09 37.2 0.7 3.6e-09 36.4 0.7 1.5 1 0 0 1 1 1 1 F-box-like RCC1 PF00415.18 GAN08189.1 - 6.3e-08 33.1 2.6 9.6e-05 22.9 0.0 5.4 4 2 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAN08189.1 - 1.2e-06 28.1 10.2 0.031 14.1 2.1 5.2 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 GAN08189.1 - 1.9e-06 27.6 1.2 3.8e-06 26.6 1.2 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAN08189.1 - 5.5e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 F-box Elongin_A PF06881.11 GAN08189.1 - 0.0094 16.5 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Ras PF00071.22 GAN08191.1 - 1.1e-51 174.7 0.0 1.4e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN08191.1 - 6.5e-22 78.0 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN08191.1 - 5.2e-07 29.3 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN08191.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CTNNBL PF08216.11 GAN08191.1 - 0.15 12.2 0.0 8.7 6.6 0.0 2.4 2 1 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear FAD-oxidase_C PF02913.19 GAN08192.1 - 1.1e-57 195.6 0.1 1.4e-57 195.2 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAN08192.1 - 2.3e-35 121.3 0.3 5.5e-35 120.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 GAN08193.1 - 4.5e-54 183.7 40.0 2.3e-37 128.8 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN08193.1 - 1.1e-06 27.4 27.8 4.5e-05 22.2 11.6 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 GAN08193.1 - 2.3e-05 23.0 27.5 0.012 14.0 10.4 2.8 2 1 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 GAN08193.1 - 5.2e-05 21.7 17.4 0.00085 17.7 0.0 3.4 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 GAN08193.1 - 0.00012 21.5 25.6 0.014 14.8 8.7 2.7 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Glyco_transf_15 PF01793.16 GAN08194.1 - 7.4e-67 225.9 15.8 9.1e-67 225.6 15.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Galactosyl_T PF01762.21 GAN08194.1 - 0.025 14.4 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Galactosyltransferase RMMBL PF07521.12 GAN08194.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Mannosyl_trans3 PF11051.8 GAN08195.1 - 1.5e-44 152.5 0.2 2.5e-43 148.4 0.2 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 GAN08195.1 - 0.0062 16.5 0.3 0.014 15.4 0.3 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase ADH_N PF08240.12 GAN08196.1 - 2.7e-24 85.2 3.5 4.4e-24 84.5 3.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN08196.1 - 2.5e-15 56.6 0.0 5.5e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAN08196.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_1c PF00749.21 GAN08197.1 - 1.5e-108 362.4 0.0 2.1e-108 361.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAN08197.1 - 9.7e-42 142.8 0.3 2.9e-41 141.3 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 GAN08197.1 - 1.2e-09 38.4 1.4 2.2e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 Glutamate--tRNA ligase N-terminal domain GST_C_2 PF13410.6 GAN08197.1 - 0.0083 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN08197.1 - 0.018 15.3 0.1 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAN08197.1 - 0.019 15.2 0.1 0.093 12.9 0.1 2.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF726 PF05277.12 GAN08198.1 - 2.9e-117 391.4 0.1 6.1e-117 390.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 GAN08198.1 - 0.01 15.8 5.6 0.012 15.7 0.2 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III UPF0220 PF05255.11 GAN08198.1 - 0.069 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Fib_alpha PF08702.10 GAN08199.1 - 0.031 14.5 15.0 0.042 14.0 11.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 GAN08199.1 - 0.42 9.5 3.2 0.7 8.7 3.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein hNIFK_binding PF12196.8 GAN08200.1 - 0.0014 18.1 0.1 0.0029 17.0 0.1 1.5 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK DUF3583 PF12126.8 GAN08200.1 - 0.0087 15.6 0.3 0.016 14.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-met PF12874.7 GAN08201.1 - 3.2e-06 27.3 2.6 6.4e-06 26.4 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN08201.1 - 4.3e-06 26.9 3.9 8.3e-06 26.0 3.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAN08201.1 - 0.0066 16.8 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) TPR_14 PF13428.6 GAN08201.1 - 0.052 14.4 2.8 1.4 9.9 0.5 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-DBF PF07535.12 GAN08201.1 - 0.053 13.6 0.6 0.13 12.4 0.6 1.6 1 0 0 1 1 1 0 DBF zinc finger AAA_lid_7 PF17867.1 GAN08201.1 - 0.09 13.0 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Midasin AAA lid domain zf-C2H2_4 PF13894.6 GAN08201.1 - 0.19 12.7 0.6 0.5 11.4 0.6 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN08201.1 - 0.41 11.2 1.6 0.89 10.1 1.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rpn3_C PF08375.11 GAN08202.1 - 3.5e-29 101.0 2.2 3.5e-29 101.0 2.2 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 GAN08202.1 - 1.5e-21 76.8 1.0 8e-21 74.5 0.0 2.7 4 0 0 4 4 4 1 PCI domain TPR_2 PF07719.17 GAN08202.1 - 0.22 11.7 7.1 0.079 13.1 1.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TMPIT PF07851.13 GAN08202.1 - 0.94 8.7 5.2 0.31 10.2 0.3 2.2 2 0 0 2 2 2 0 TMPIT-like protein CDP-OH_P_transf PF01066.21 GAN08203.1 - 2.4e-18 66.7 0.0 2.4e-18 66.7 0.0 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CTP_transf_1 PF01148.20 GAN08205.1 - 1.4e-79 267.7 26.0 1.8e-79 267.3 26.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family PBP_N PF17093.5 GAN08205.1 - 0.24 11.7 1.9 6.4 7.0 0.0 2.6 2 1 0 2 2 2 0 Penicillin-binding protein N-terminus SdpI PF13630.6 GAN08205.1 - 5.8 7.1 12.7 9.3 6.5 2.3 3.5 2 1 1 3 3 3 0 SdpI/YhfL protein family Actin PF00022.19 GAN08206.1 - 1.9e-146 487.8 0.0 2.2e-146 487.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAN08206.1 - 1.3e-09 37.3 0.0 4.6e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 GAN08206.1 - 0.3 10.3 0.8 3.9 6.7 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Peptidase_M16 PF00675.20 GAN08207.1 - 3.8e-21 75.6 1.0 7.2e-21 74.7 1.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAN08207.1 - 4.8e-19 69.1 0.0 1.1e-18 67.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain Forkhead PF00250.18 GAN08208.1 - 1.1e-38 131.3 0.7 2.8e-38 130.1 0.1 2.1 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 GAN08208.1 - 2.9e-10 40.3 0.0 7.4e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 GAN08208.1 - 0.17 12.3 0.7 0.51 10.8 0.1 2.1 2 0 0 2 2 2 0 linker histone H1 and H5 family DUF966 PF06136.13 GAN08208.1 - 7.6 6.2 21.2 2.2 7.9 15.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FMN_dh PF01070.18 GAN08209.1 - 1.8e-121 405.4 0.0 2.2e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAN08209.1 - 1.4e-25 89.2 0.0 4e-25 87.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAN08209.1 - 3.5e-08 33.0 0.0 6.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAN08209.1 - 0.00024 20.2 0.1 0.00045 19.3 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAN08209.1 - 0.013 14.9 0.1 0.032 13.6 0.1 1.4 1 1 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 GAN08209.1 - 0.021 14.1 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NIF PF03031.18 GAN08210.1 - 3e-52 176.5 0.5 5e-52 175.8 0.5 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAN08210.1 - 0.049 14.0 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF406 PF04175.12 GAN08210.1 - 0.63 10.6 0.0 0.63 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF406) PHD PF00628.29 GAN08211.1 - 6e-07 29.3 7.3 1.4e-06 28.1 7.3 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 GAN08211.1 - 2.4e-05 24.2 1.5 2.4e-05 24.2 1.5 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 WHIM1 PF15612.6 GAN08211.1 - 0.036 13.6 0.2 0.074 12.6 0.2 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 GAN08211.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 DDT domain WSD PF15613.6 GAN08211.1 - 0.25 11.8 5.5 0.29 11.6 0.1 3.6 4 0 0 4 4 4 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF5320 PF17253.2 GAN08211.1 - 0.28 12.3 2.6 0.98 10.5 2.6 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5320) zinc_ribbon_10 PF10058.9 GAN08211.1 - 0.61 9.9 2.5 0.35 10.6 0.2 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_2 PF13831.6 GAN08211.1 - 1.9 8.1 3.9 5.9 6.5 3.9 1.9 1 1 0 1 1 1 0 PHD-finger Abhydrolase_3 PF07859.13 GAN08212.1 - 6.1e-24 85.1 0.0 9.4e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN08212.1 - 7.1e-16 58.0 0.2 1.1e-15 57.3 0.1 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAN08212.1 - 0.0033 16.9 0.0 0.0096 15.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1570 PF07607.11 GAN08212.1 - 0.099 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) VPS9 PF02204.18 GAN08213.1 - 6.8e-15 55.2 2.3 1.1e-14 54.5 0.1 2.3 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Arrestin_N PF00339.29 GAN08214.1 - 2.6e-19 69.7 0.0 2.6e-19 69.7 0.0 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN08214.1 - 2.5e-12 47.4 3.9 2.8e-07 31.0 0.1 3.5 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 GAN08214.1 - 0.02 14.6 1.6 0.029 14.1 0.0 2.1 2 1 1 3 3 3 0 Arrestin_N terminal like Carn_acyltransf PF00755.20 GAN08215.1 - 1.5e-175 585.2 0.8 1.7e-175 585.0 0.8 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase IL2 PF00715.17 GAN08215.1 - 0.07 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Interleukin 2 Neurexophilin PF06312.12 GAN08217.1 - 0.051 13.0 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Neurexophilin CH PF00307.31 GAN08218.1 - 1.3e-27 96.1 0.2 6.4e-13 48.8 0.0 3.5 3 0 0 3 3 3 2 Calponin homology (CH) domain GAS2 PF02187.17 GAN08218.1 - 1.1e-11 44.7 0.1 4.2e-11 42.8 0.1 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.8 GAN08218.1 - 0.0003 20.6 0.1 0.024 14.4 0.0 3.2 3 0 0 3 3 3 1 CAMSAP CH domain YhdB PF14148.6 GAN08218.1 - 1.5 8.9 4.6 2.4 8.3 0.2 3.9 3 0 0 3 3 3 0 YhdB-like protein Endonuc-BglII PF09195.11 GAN08218.1 - 4.9 6.9 10.7 8.7 6.2 4.5 4.4 2 1 0 2 2 2 0 Restriction endonuclease BglII PSK_trans_fac PF07704.11 GAN08218.1 - 5.9 7.7 15.4 0.3 11.9 1.2 6.6 3 0 0 3 3 3 0 Rv0623-like transcription factor SAP PF02037.27 GAN08219.1 - 8.2e-14 51.0 1.5 2.1e-13 49.7 0.3 2.2 2 0 0 2 2 2 1 SAP domain RSB_motif PF16294.5 GAN08219.1 - 1.4e-08 34.9 1.0 1.4e-08 34.9 1.0 3.4 2 1 0 3 3 3 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 GAN08219.1 - 4.6e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.7 GAN08219.1 - 0.00027 20.6 0.5 0.001 18.7 0.2 2.2 3 0 0 3 3 3 1 HeH/LEM domain Ish1 PF10281.9 GAN08219.1 - 0.0033 17.7 0.1 0.93 9.8 0.0 3.1 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein RRM_3 PF08777.11 GAN08219.1 - 0.0053 16.8 0.1 0.0053 16.8 0.1 3.1 2 2 2 4 4 4 1 RNA binding motif SYCP2_ARLD PF18581.1 GAN08219.1 - 0.047 13.7 0.4 0.098 12.7 0.4 1.5 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain P53_C PF11619.8 GAN08219.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain Metallophos PF00149.28 GAN08221.1 - 3e-40 138.9 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN08221.1 - 3.5e-23 81.8 0.6 1.6e-22 79.7 0.2 2.1 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain ANAPC10 PF03256.16 GAN08222.1 - 1.4e-46 158.5 0.1 2e-46 158.0 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 GAN08222.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 F5/8 type C domain DSPc PF00782.20 GAN08223.1 - 1e-07 31.8 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN08223.1 - 2.8e-06 27.1 0.0 2.4e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAN08223.1 - 0.048 13.8 0.0 0.2 11.7 0.0 1.8 1 1 1 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 GAN08223.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SAM_2 PF07647.17 GAN08224.1 - 5.2e-09 36.1 0.1 1.4e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN08224.1 - 5.6e-06 26.7 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) U62_UL91 PF17442.2 GAN08225.1 - 0.14 12.2 0.1 0.59 10.2 0.1 2.1 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins Aldo_ket_red PF00248.21 GAN08226.1 - 1.1e-56 192.2 0.0 4.4e-56 190.2 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.27 GAN08227.1 - 1.3e-59 198.2 5.8 9.5e-21 73.5 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2043 PF09740.9 GAN08227.1 - 7.7e-30 103.7 1.9 1.1e-29 103.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) Tim17 PF02466.19 GAN08227.1 - 0.0047 17.3 8.9 0.27 11.6 0.2 3.3 3 0 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family AAA PF00004.29 GAN08228.1 - 1.4e-50 171.2 0.0 4.2e-41 140.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN08228.1 - 9.3e-17 60.6 0.2 5.7e-10 38.8 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAN08228.1 - 9.3e-11 42.4 0.1 0.00097 19.6 0.1 3.8 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAN08228.1 - 2.9e-09 37.3 0.2 0.056 13.7 0.0 4.8 2 2 2 4 4 4 2 AAA domain NACHT PF05729.12 GAN08228.1 - 4.4e-06 26.7 0.0 0.091 12.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 GAN08228.1 - 4.9e-06 26.6 0.0 0.024 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAN08228.1 - 8.7e-06 25.4 0.0 0.032 13.7 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 GAN08228.1 - 2.4e-05 24.4 0.0 0.0066 16.4 0.0 2.9 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAN08228.1 - 2.5e-05 24.8 0.0 0.21 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAN08228.1 - 2.6e-05 24.6 0.0 0.027 14.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 GAN08228.1 - 2.8e-05 24.1 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 GAN08228.1 - 3e-05 24.0 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 GAN08228.1 - 4.3e-05 22.8 0.0 0.0075 15.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 GAN08228.1 - 7.3e-05 22.8 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAN08228.1 - 8.5e-05 23.1 0.2 0.02 15.4 0.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA_5 PF07728.14 GAN08228.1 - 8.7e-05 22.5 0.1 0.11 12.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAN08228.1 - 0.00014 22.0 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAN08228.1 - 0.00015 21.6 0.1 0.67 9.7 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 GAN08228.1 - 0.00026 20.7 0.0 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 GAN08228.1 - 0.00045 20.0 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 GAN08228.1 - 0.0009 18.5 0.0 1.2 8.3 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain RuvB_N PF05496.12 GAN08228.1 - 0.00092 19.0 0.1 0.073 12.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 GAN08228.1 - 0.00093 18.6 0.0 0.2 11.0 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 GAN08228.1 - 0.001 18.8 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 GAN08228.1 - 0.0023 17.8 0.0 0.65 9.8 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_2 PF07724.14 GAN08228.1 - 0.0024 18.0 0.0 0.063 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GAN08228.1 - 0.0028 16.9 0.1 0.056 12.7 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain Roc PF08477.13 GAN08228.1 - 0.0063 16.7 0.1 4.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 GAN08228.1 - 0.0075 16.0 0.1 0.65 9.7 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein SRPRB PF09439.10 GAN08228.1 - 0.0083 15.6 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 GAN08228.1 - 0.011 15.4 0.0 7.1 6.3 0.0 2.7 2 1 1 3 3 3 0 Sigma-54 interaction domain Adeno_IVa2 PF02456.15 GAN08228.1 - 0.017 14.0 0.1 0.03 13.1 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Mg_chelatase PF01078.21 GAN08228.1 - 0.022 14.1 0.0 1.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAN08228.1 - 0.034 14.4 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 GAN08228.1 - 0.037 13.9 0.1 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 GAN08228.1 - 0.049 13.5 0.1 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 GAN08228.1 - 0.049 14.1 0.2 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 GAN08228.1 - 0.051 13.0 0.0 5.4 6.4 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein AFG1_ATPase PF03969.16 GAN08228.1 - 0.071 12.0 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase ATP-synt_ab PF00006.25 GAN08228.1 - 0.078 12.6 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 GAN08228.1 - 0.11 11.8 0.1 1.4 8.1 0.0 2.5 2 1 1 3 3 3 0 Septin Zeta_toxin PF06414.12 GAN08228.1 - 0.12 11.6 0.1 3.3 6.9 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin AAA_25 PF13481.6 GAN08228.1 - 0.16 11.5 0.2 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 GAN08228.1 - 0.19 11.3 0.2 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Ras family RhoGAP PF00620.27 GAN08229.1 - 2.2e-35 121.7 0.0 5.9e-35 120.3 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 GAN08229.1 - 1.5e-16 60.4 0.5 1.5e-16 60.4 0.5 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Coq4 PF05019.13 GAN08229.1 - 0.0044 16.4 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GvpK PF05121.12 GAN08229.1 - 0.074 13.1 0.0 4 7.5 0.0 2.8 2 0 0 2 2 2 0 Gas vesicle protein K SVIP PF15811.5 GAN08230.1 - 5.2e-07 30.0 4.1 5.2e-07 30.0 4.1 2.4 1 1 2 3 3 3 2 Small VCP/p97-interacting protein WLM PF08325.10 GAN08230.1 - 0.14 12.3 2.8 0.087 12.9 1.3 1.4 1 1 0 1 1 1 0 WLM domain ADH_N PF08240.12 GAN08231.1 - 1.3e-23 83.0 6.6 2.1e-23 82.3 6.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN08231.1 - 5.2e-16 58.8 0.0 8.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAN08231.1 - 1.4e-06 27.8 0.0 2.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAN08231.1 - 1.5e-05 26.1 0.0 2e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAN08231.1 - 0.032 13.5 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 GAN08231.1 - 0.063 13.0 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NADH_4Fe-4S PF10589.9 GAN08231.1 - 0.54 10.4 4.7 1.4 9.0 4.7 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DIOX_N PF14226.6 GAN08232.1 - 1.1e-21 77.8 0.1 2.1e-21 76.9 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAN08232.1 - 9e-14 51.8 0.0 1.8e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.23 GAN08233.1 - 3.3e-11 43.0 0.0 7.7e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAN08233.1 - 2.1e-09 37.2 0.1 1.1e-08 34.9 0.1 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAN08233.1 - 0.00038 20.5 0.7 0.0016 18.5 0.7 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase Inv-AAD PF18785.1 GAN08233.1 - 0.088 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Afaf PF15339.6 GAN08233.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor Xan_ur_permease PF00860.20 GAN08234.1 - 1.1e-56 192.3 32.7 2.4e-55 187.8 32.7 2.1 1 1 0 1 1 1 1 Permease family NMN_transporter PF04973.12 GAN08234.1 - 0.43 10.5 6.9 0.38 10.7 1.9 2.9 2 1 1 3 3 3 0 Nicotinamide mononucleotide transporter SAP18 PF06487.12 GAN08235.1 - 1.1e-37 129.3 0.0 1.7e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Recep_L_domain PF01030.24 GAN08236.1 - 4.3e-11 42.9 10.4 2.6e-05 24.3 0.4 4.3 2 1 1 4 4 4 3 Receptor L domain Ribosomal_L10 PF00466.20 GAN08237.1 - 6.9e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 4F5 PF04419.14 GAN08238.1 - 2.6e-07 31.4 15.0 2.6e-07 31.4 15.0 2.4 2 0 0 2 2 2 1 4F5 protein family Peptidase_C97 PF05903.14 GAN08239.1 - 1.7e-23 83.1 0.1 5.1e-23 81.6 0.1 1.8 1 1 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 GAN08239.1 - 0.032 14.5 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase ORC6 PF05460.13 GAN08239.1 - 2.1 7.5 7.6 2.8 7.1 7.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) GRAB PF10375.9 GAN08240.1 - 9.7e-08 31.6 0.3 9.7e-08 31.6 0.3 2.5 3 0 0 3 3 3 1 GRIP-related Arf-binding domain FUSC PF04632.12 GAN08240.1 - 0.0005 18.7 15.0 0.0005 18.7 15.0 3.1 2 1 1 3 3 3 2 Fusaric acid resistance protein family IFT57 PF10498.9 GAN08240.1 - 0.0027 16.7 8.4 0.0027 16.7 8.4 5.3 1 1 3 5 5 4 2 Intra-flagellar transport protein 57 T3SSipB PF16535.5 GAN08240.1 - 0.0056 17.2 5.4 0.0056 17.2 5.4 5.9 3 1 3 6 6 5 1 Type III cell invasion protein SipB GRIP PF01465.20 GAN08240.1 - 0.006 16.5 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 GRIP domain ATG16 PF08614.11 GAN08240.1 - 0.029 14.6 108.8 0.78 9.9 27.1 6.0 3 1 3 6 6 6 0 Autophagy protein 16 (ATG16) WD40_alt PF14077.6 GAN08240.1 - 0.11 12.4 6.0 1.6 8.6 0.3 3.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif Baculo_PEP_C PF04513.12 GAN08240.1 - 0.15 12.1 52.7 0.39 10.7 3.4 6.0 3 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 GAN08240.1 - 2.3 8.2 65.2 0.13 12.3 7.6 6.8 3 1 4 7 7 7 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 GAN08240.1 - 4.1 7.5 117.4 1.8 8.6 15.2 6.4 3 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein T4bSS_IcmS PF12608.8 GAN08240.1 - 6.4 7.2 6.5 1.4 9.3 1.7 2.4 2 0 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment F-box-like PF12937.7 GAN08241.1 - 6e-08 32.5 0.1 1.3e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN08241.1 - 0.0022 17.8 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain FKBP_C PF00254.28 GAN08242.1 - 4.1e-35 120.0 0.0 4.7e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AA_permease_2 PF13520.6 GAN08243.1 - 7.6e-47 160.1 45.0 9.4e-47 159.8 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease NADH-u_ox-rdase PF10785.9 GAN08243.1 - 0.28 11.9 1.3 1 10.1 0.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Cyclin_N PF00134.23 GAN08245.1 - 1.3e-11 44.4 0.1 5.5e-09 35.9 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 GAN08245.1 - 0.0014 19.0 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 GAN08245.1 - 0.031 14.3 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat TMEM237 PF15383.6 GAN08246.1 - 0.0017 17.5 0.1 0.0017 17.5 0.1 2.2 1 1 1 2 2 2 1 Transmembrane protein 237 Trp_oprn_chp PF09534.10 GAN08246.1 - 0.027 14.3 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gram_pos_anchor PF00746.21 GAN08246.1 - 0.048 13.6 0.2 0.048 13.6 0.2 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif SKG6 PF08693.10 GAN08246.1 - 0.13 11.7 0.9 0.38 10.2 0.9 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 GAN08246.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 GAN08246.1 - 0.22 11.8 4.5 3.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Orf78 (ac78) Otopetrin PF03189.13 GAN08246.1 - 0.27 10.0 1.0 0.37 9.6 1.0 1.3 1 0 0 1 1 1 0 Otopetrin bZIP_2 PF07716.15 GAN08247.1 - 8.7e-13 48.1 15.7 8.7e-13 48.1 15.7 2.7 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN08247.1 - 9.8e-12 44.8 14.2 9.8e-12 44.8 14.2 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAN08247.1 - 1.9e-07 31.5 9.7 1.9e-07 31.5 9.7 2.8 3 0 0 3 3 2 1 bZIP Maf transcription factor DUF812 PF05667.11 GAN08247.1 - 0.00013 21.0 0.0 0.00013 21.0 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF812) HOOK PF05622.12 GAN08247.1 - 0.00032 19.0 6.4 0.00057 18.2 6.4 1.3 1 0 0 1 1 1 1 HOOK protein TMCO5 PF14992.6 GAN08247.1 - 0.00095 18.8 5.2 0.0021 17.7 5.2 1.5 1 0 0 1 1 1 1 TMCO5 family TBK1_CCD1 PF18394.1 GAN08247.1 - 0.0039 16.8 0.5 0.0065 16.1 0.5 1.2 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Ax_dynein_light PF10211.9 GAN08247.1 - 0.011 15.7 3.2 0.011 15.7 3.2 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DivIC PF04977.15 GAN08247.1 - 0.013 15.3 6.6 0.013 15.3 6.6 3.2 4 0 0 4 4 3 0 Septum formation initiator HALZ PF02183.18 GAN08247.1 - 0.014 15.6 7.7 0.25 11.6 3.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fungal_TACC PF12709.7 GAN08247.1 - 0.016 15.6 2.5 0.066 13.7 1.8 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins AKNA PF12443.8 GAN08247.1 - 0.025 15.2 1.3 0.025 15.2 1.3 3.2 3 0 0 3 3 2 0 AT-hook-containing transcription factor TSC22 PF01166.18 GAN08247.1 - 0.026 14.8 2.5 0.026 14.8 2.5 2.4 2 0 0 2 2 1 0 TSC-22/dip/bun family DUF4094 PF13334.6 GAN08247.1 - 0.11 12.9 2.6 0.57 10.6 2.6 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Seadorna_VP6 PF07407.11 GAN08247.1 - 0.22 10.4 0.7 0.31 9.9 0.7 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein YabA PF06156.13 GAN08247.1 - 0.42 11.3 8.1 0.04 14.6 2.7 2.2 2 1 0 2 2 1 0 Initiation control protein YabA DUF724 PF05266.14 GAN08247.1 - 0.45 10.3 5.9 1 9.1 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CCD48 PF15799.5 GAN08247.1 - 0.55 8.5 11.9 0.0073 14.7 3.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 Atg14 PF10186.9 GAN08247.1 - 0.74 8.8 9.0 0.057 12.5 4.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS6_N PF14661.6 GAN08247.1 - 1.5 8.3 8.5 0.26 10.8 2.7 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Spc24 PF08286.11 GAN08247.1 - 2.4 8.5 7.3 0.52 10.6 1.4 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 GAN08247.1 - 2.5 8.2 10.1 0.18 11.9 4.7 1.8 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 GAN08247.1 - 3.4 7.6 54.8 0.2 11.6 26.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 GAN08247.1 - 7.9 6.0 27.5 0.54 9.8 13.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) O-FucT PF10250.9 GAN08248.1 - 9.2e-21 74.9 4.1 1.1e-19 71.3 4.1 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RPN7 PF10602.9 GAN08248.1 - 0.046 13.4 0.1 0.72 9.5 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 HLH PF00010.26 GAN08249.1 - 1.5e-11 44.0 0.4 3.1e-11 43.0 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Raftlin PF15250.6 GAN08249.1 - 0.78 8.4 5.5 0.78 8.4 5.5 1.0 1 0 0 1 1 1 0 Raftlin Pkinase PF00069.25 GAN08250.1 - 3.2e-59 200.5 0.0 5.1e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08250.1 - 8.4e-24 84.2 0.0 1.3e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN08250.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN08250.1 - 4.6e-05 22.4 0.0 9.4e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 GAN08250.1 - 0.00017 21.2 0.9 0.0017 18.0 0.1 2.4 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 GAN08250.1 - 0.00021 20.4 0.3 0.00043 19.3 0.0 1.7 2 1 0 2 2 2 1 Haspin like kinase domain PAS_9 PF13426.7 GAN08250.1 - 0.00085 19.5 0.1 0.21 11.9 0.0 3.0 2 1 0 2 2 2 1 PAS domain APH PF01636.23 GAN08250.1 - 0.0014 18.6 0.1 0.0056 16.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN08250.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BphX PF06139.12 GAN08250.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 BphX-like RRN3 PF05327.11 GAN08251.1 - 2.4e-171 571.1 5.1 2.4e-171 571.1 5.1 1.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 SapB_2 PF03489.17 GAN08251.1 - 0.75 10.0 6.8 3.9 7.7 0.3 3.8 4 0 0 4 4 4 0 Saposin-like type B, region 2 zf-C2H2 PF00096.26 GAN08252.1 - 6.4e-14 51.5 15.5 6.2e-06 26.4 3.1 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN08252.1 - 9.6e-06 25.8 20.8 0.00041 20.7 1.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN08252.1 - 2.7e-05 24.6 25.9 0.007 17.1 2.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger Ogr_Delta PF04606.12 GAN08252.1 - 0.011 15.7 0.7 0.042 13.8 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 GAN08252.1 - 0.012 15.8 4.7 0.98 9.8 1.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAN08252.1 - 0.082 12.9 6.0 0.14 12.2 2.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 GAN08252.1 - 0.15 12.5 3.8 4.7 7.7 0.8 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 GAN08252.1 - 0.3 11.0 7.4 4.2 7.4 0.2 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FXR_C1 PF16096.5 GAN08252.1 - 0.47 10.7 5.9 0.69 10.2 1.6 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 zf-C2H2_11 PF16622.5 GAN08252.1 - 5.2 6.9 9.1 2.8 7.8 0.0 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type SAICAR_synt PF01259.18 GAN08253.1 - 2.5e-100 335.2 0.1 3.1e-100 334.9 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase BAF1_ABF1 PF04684.13 GAN08254.1 - 8.8 5.2 12.4 12 4.8 12.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nt_Gln_amidase PF09764.9 GAN08255.1 - 1.9e-62 210.2 0.3 2.3e-62 209.9 0.3 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase TyeA PF09059.10 GAN08255.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 TyeA PAH PF02671.21 GAN08255.1 - 0.029 14.5 0.3 0.071 13.3 0.1 1.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat RHD_dimer PF16179.5 GAN08255.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Rel homology dimerisation domain DUF836 PF05768.14 GAN08256.1 - 4.5e-10 39.8 0.2 5.2e-10 39.6 0.2 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 GAN08256.1 - 8.9e-05 22.5 0.0 0.00012 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 GAN08256.1 - 0.0043 16.9 0.0 0.016 15.1 0.0 1.7 1 1 1 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 GAN08256.1 - 0.039 14.2 0.1 0.06 13.6 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF1223 PF06764.11 GAN08256.1 - 0.096 12.7 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Bmt2 PF11968.8 GAN08257.1 - 1.7e-70 237.3 0.0 2.1e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 GAN08257.1 - 0.00047 20.0 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Corona_NS8 PF12093.8 GAN08257.1 - 0.15 12.7 0.1 0.51 10.9 0.0 1.8 2 0 0 2 2 2 0 Coronavirus NS8 protein BHD_3 PF10405.9 GAN08258.1 - 3e-23 82.0 0.0 9.6e-23 80.4 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 GAN08258.1 - 2.4e-20 72.7 1.2 2.4e-20 72.7 1.2 2.8 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 GAN08258.1 - 2.9e-17 62.2 0.0 7.2e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 GAN08258.1 - 7.8e-13 49.2 0.2 7.8e-13 49.2 0.2 3.9 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 GAN08258.1 - 5.8e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ank_2 PF12796.7 GAN08259.1 - 8.3e-11 42.3 4.8 3.1e-05 24.5 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN08259.1 - 3.5e-10 40.2 2.0 0.085 13.5 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAN08259.1 - 0.00011 22.5 6.1 0.0026 18.1 0.1 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 GAN08259.1 - 0.00059 20.1 2.2 0.05 14.2 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 GAN08259.1 - 0.0037 17.5 3.4 1.2 9.6 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 GAN08259.1 - 0.0042 16.9 5.0 0.0079 16.0 0.6 3.2 2 2 0 2 2 2 1 KilA-N domain BioT2 PF15368.6 GAN08259.1 - 0.026 14.5 0.6 0.099 12.6 0.6 2.0 1 0 0 1 1 1 0 Spermatogenesis family BioT2 Rep_fac-A_3 PF08661.11 GAN08259.1 - 0.076 13.4 0.1 0.25 11.7 0.1 1.8 1 0 0 1 1 1 0 Replication factor A protein 3 CENP-F_leu_zip PF10473.9 GAN08259.1 - 0.15 12.1 11.1 0.89 9.6 5.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TACC_C PF05010.14 GAN08259.1 - 0.64 9.8 12.6 0.31 10.8 4.4 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal EMP24_GP25L PF01105.24 GAN08259.1 - 1.4 8.9 7.0 8.2 6.3 1.7 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.12 GAN08259.1 - 1.6 8.8 7.6 3.2 7.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 GAN08259.1 - 1.9 8.7 12.2 2.4 8.4 4.8 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF148 PF02520.17 GAN08259.1 - 8.3 6.6 13.4 7 6.8 0.4 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF148 RasGAP PF00616.19 GAN08261.1 - 8.5e-59 198.7 0.0 8.5e-59 198.7 0.0 2.7 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAN08261.1 - 1.4e-41 141.9 0.8 1.4e-41 141.9 0.8 2.2 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.22 GAN08261.1 - 0.026 14.4 0.2 11 6.1 0.1 3.1 2 0 0 2 2 2 0 MarR family ADK PF00406.22 GAN08261.1 - 0.14 12.2 1.7 2.5 8.2 0.0 3.2 3 1 0 3 3 3 0 Adenylate kinase HxlR PF01638.17 GAN08261.1 - 0.75 9.7 3.3 1.9 8.4 0.2 3.0 3 0 0 3 3 3 0 HxlR-like helix-turn-helix Ribosomal_L29 PF00831.23 GAN08261.1 - 0.92 9.5 6.1 13 5.8 2.3 3.5 3 0 0 3 3 3 0 Ribosomal L29 protein DUF5344 PF17279.2 GAN08261.1 - 1.1 9.9 4.6 29 5.3 0.8 3.5 2 0 0 2 2 2 0 Family of unknown function (DUF5344) UPF0220 PF05255.11 GAN08262.1 - 5.6e-53 178.9 1.9 6.2e-53 178.7 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Methyltransf_28 PF02636.17 GAN08263.1 - 5e-26 91.9 0.0 7.9e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Redoxin PF08534.10 GAN08264.1 - 1.8e-29 102.4 0.0 2e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAN08264.1 - 9.3e-08 32.0 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family NAD_binding_10 PF13460.6 GAN08264.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Homeodomain PF00046.29 GAN08265.1 - 5.7e-20 70.9 3.2 1.4e-19 69.6 2.5 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 GAN08265.1 - 0.14 12.1 2.7 0.11 12.5 0.6 2.0 2 0 0 2 2 2 0 Homeobox KN domain Peptidase_S10 PF00450.22 GAN08267.1 - 1.7e-89 301.1 0.5 2.1e-89 300.8 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ribosomal_S21 PF01165.20 GAN08268.1 - 0.0028 17.3 0.8 0.013 15.2 0.8 2.2 1 0 0 1 1 1 1 Ribosomal protein S21 Sas10 PF09368.10 GAN08269.1 - 1.7e-28 98.9 8.4 1.7e-28 98.9 8.4 2.6 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 GAN08269.1 - 1.8e-11 44.5 0.3 1.8e-11 44.5 0.3 3.2 3 0 0 3 3 3 1 Sas10/Utp3/C1D family DUF4477 PF14780.6 GAN08269.1 - 0.21 11.2 0.5 0.61 9.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) SPAN-X PF07458.12 GAN08269.1 - 8.5 6.9 16.4 0.91 10.0 6.5 4.0 3 1 1 4 4 4 0 Sperm protein associated with nucleus, mapped to X chromosome Bud13 PF09736.9 GAN08270.1 - 3.8e-50 170.1 11.8 3.8e-50 170.1 11.8 3.4 1 1 2 3 3 3 1 Pre-mRNA-splicing factor of RES complex Saf_2TM PF18303.1 GAN08270.1 - 0.14 11.7 0.4 0.25 10.9 0.4 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Androgen_recep PF02166.16 GAN08270.1 - 6.2 5.5 8.4 12 4.6 8.2 1.5 1 1 0 1 1 1 0 Androgen receptor Homeodomain PF00046.29 GAN08271.1 - 2e-15 56.3 0.8 2e-15 56.3 0.8 2.2 4 0 0 4 4 4 1 Homeodomain Homeobox_KN PF05920.11 GAN08271.1 - 0.0024 17.7 0.1 0.006 16.5 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 GAN08271.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain PIN_8 PF18476.1 GAN08271.1 - 0.097 12.5 0.3 0.13 12.1 0.3 1.1 1 0 0 1 1 1 0 PIN like domain DUF4022 PF13214.6 GAN08272.1 - 0.25 11.7 5.6 0.31 11.3 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) Myosin_head PF00063.21 GAN08274.1 - 4.9e-266 884.3 3.4 7.1e-266 883.8 3.4 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 GAN08274.1 - 5.1e-26 91.0 4.1 5.1e-26 91.0 4.1 2.6 2 0 0 2 2 1 1 DIL domain IQ PF00612.27 GAN08274.1 - 6.4e-16 56.6 27.7 4.9e-05 22.8 0.3 6.1 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_16 PF13191.6 GAN08274.1 - 0.0065 16.9 3.0 0.013 15.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 GAN08274.1 - 0.012 15.7 0.5 0.061 13.4 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rota_NSP3 PF01665.16 GAN08274.1 - 0.078 12.1 4.7 0.15 11.1 4.7 1.4 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 AAA_22 PF13401.6 GAN08274.1 - 0.079 13.2 0.0 0.37 11.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAN08274.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Myosin_N PF02736.19 GAN08274.1 - 0.43 10.4 6.0 0.12 12.2 1.5 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain ABC_tran PF00005.27 GAN08274.1 - 0.62 10.6 0.0 0.62 10.6 0.0 3.1 2 1 0 2 2 1 0 ABC transporter TSC22 PF01166.18 GAN08274.1 - 1.2 9.5 7.2 30 5.0 0.4 4.3 3 1 0 3 3 3 0 TSC-22/dip/bun family DUF4337 PF14235.6 GAN08274.1 - 1.6 8.8 15.2 0.14 12.3 4.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DivIC PF04977.15 GAN08274.1 - 1.7 8.5 20.5 0.41 10.5 2.6 4.3 2 1 0 3 3 3 0 Septum formation initiator KELK PF15796.5 GAN08274.1 - 9.9 6.7 17.4 1.4 9.4 8.2 3.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Myb_DNA-binding PF00249.31 GAN08276.1 - 6.6e-46 154.3 8.7 4.8e-17 61.9 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN08276.1 - 1.1e-36 124.8 3.0 1.9e-17 63.3 0.2 4.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain zf-C2H2_aberr PF17017.5 GAN08276.1 - 0.0011 19.1 8.2 0.14 12.3 0.5 3.3 2 1 1 3 3 3 2 Aberrant zinc-finger Rap1_C PF11626.8 GAN08276.1 - 0.0021 18.1 4.7 0.42 10.7 0.5 3.6 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 GAN08276.1 - 0.0096 16.1 0.3 6.1 7.1 0.0 2.7 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 zf-C2H2 PF00096.26 GAN08276.1 - 0.037 14.5 23.2 0.16 12.5 0.7 4.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 GAN08276.1 - 0.039 14.2 2.0 0.076 13.3 0.0 2.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 GAN08276.1 - 1.1 10.2 18.3 1.3 10.0 0.1 5.2 6 0 0 6 6 6 0 C2H2-type zinc finger Myb_DNA-bind_7 PF15963.5 GAN08276.1 - 2.3 8.2 5.4 2.9 7.8 0.0 3.4 3 1 1 4 4 4 0 Myb DNA-binding like COesterase PF00135.28 GAN08277.1 - 6.1e-73 246.4 0.0 2.6e-42 145.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAN08277.1 - 0.001 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN08277.1 - 0.099 11.5 0.0 7.9 5.2 0.0 2.4 2 0 0 2 2 2 0 Steryl acetyl hydrolase Sec7 PF01369.20 GAN08278.1 - 2.2e-51 174.1 0.0 9.8e-51 172.0 0.0 2.0 1 1 0 1 1 1 1 Sec7 domain PH PF00169.29 GAN08278.1 - 0.00017 22.1 3.0 0.036 14.6 0.1 3.2 3 0 0 3 3 3 2 PH domain PH_10 PF15411.6 GAN08278.1 - 0.0026 18.0 0.0 0.0026 18.0 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 GAN08278.1 - 0.044 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 PH domain CMV_1a PF12467.8 GAN08278.1 - 1.9 8.8 11.8 7.8 6.8 4.0 2.8 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein family DUF3926 PF13080.6 GAN08280.1 - 0.09 12.7 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) BRO1 PF03097.18 GAN08281.1 - 1.7e-105 353.1 2.5 1.7e-105 353.1 2.5 3.0 2 2 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAN08281.1 - 3.3e-75 253.1 12.9 5.3e-75 252.5 12.9 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF5595 PF18077.1 GAN08281.1 - 0.0011 19.1 3.5 0.057 13.5 1.4 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5595) ddrB-ParB PF18763.1 GAN08281.1 - 0.078 13.1 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain TFIIE_alpha PF02002.17 GAN08282.1 - 6.6e-15 54.9 0.2 1.5e-14 53.7 0.2 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 GAN08282.1 - 8.7e-06 26.0 5.5 8.7e-06 26.0 5.5 2.8 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha B-block_TFIIIC PF04182.12 GAN08282.1 - 0.0053 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TTSSLRR PF12468.8 GAN08282.1 - 0.031 14.5 2.1 0.073 13.3 0.5 2.5 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Zn-ribbon_8 PF09723.10 GAN08282.1 - 0.12 12.5 1.8 0.96 9.6 1.8 2.4 1 1 1 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 GAN08282.1 - 0.19 11.2 5.0 0.91 9.1 4.6 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding WD40 PF00400.32 GAN08283.1 - 1.3e-17 63.8 18.1 0.0024 18.7 0.1 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08283.1 - 0.00072 19.8 0.9 1.5 9.1 0.0 4.5 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Pol_alpha_B_N PF08418.10 GAN08284.1 - 0.056 13.4 6.4 0.085 12.8 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal WW PF00397.26 GAN08286.1 - 5.7e-13 48.7 3.6 1.5e-12 47.3 3.6 1.8 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 GAN08286.1 - 3.2e-06 27.4 10.0 3.8e-06 27.2 10.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3824 PF12868.7 GAN08286.1 - 0.01 16.5 0.2 0.01 16.5 0.2 2.3 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) AP4E_app_platf PF14807.6 GAN08287.1 - 0.077 13.4 0.2 13 6.2 0.1 3.2 3 0 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform FlgT_C PF16538.5 GAN08287.1 - 0.1 13.1 0.6 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain MIP PF00230.20 GAN08288.1 - 3.9e-45 154.3 7.7 6.6e-45 153.6 7.7 1.3 1 0 0 1 1 1 1 Major intrinsic protein Methyltr_RsmB-F PF01189.17 GAN08288.1 - 7e-28 97.6 0.0 3.8e-27 95.3 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 GAN08288.1 - 0.081 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GAN08288.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTHFR PF02219.17 GAN08289.1 - 2.1e-116 388.3 0.0 2.7e-116 387.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_25 PF13649.6 GAN08290.1 - 3e-11 43.9 0.0 8.2e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08290.1 - 2.1e-09 37.3 0.0 5.6e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08290.1 - 8.4e-09 35.5 0.3 2.6e-08 33.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN08290.1 - 3e-08 34.2 0.0 8.9e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN08290.1 - 5.3e-06 25.9 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN08290.1 - 1.4e-05 24.6 0.2 0.00018 21.0 0.0 2.7 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAN08290.1 - 2.2e-05 25.1 0.0 0.00013 22.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAN08290.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 GAN08290.1 - 0.034 13.7 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 GAN08290.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 GAN08291.1 - 1.4e-82 277.6 0.0 2.7e-82 276.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN08291.1 - 0.0055 17.7 0.0 0.013 16.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4252 PF14060.6 GAN08291.1 - 0.23 11.3 1.7 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Zip PF02535.22 GAN08292.1 - 6.4e-57 193.3 13.6 6.4e-57 193.3 13.6 2.1 1 1 1 2 2 2 1 ZIP Zinc transporter Aconitase_C PF00694.19 GAN08292.1 - 0.02 15.3 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Aconitase C-terminal domain DUF1129 PF06570.11 GAN08292.1 - 0.067 12.7 0.8 1.8 8.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Mntp PF02659.15 GAN08292.1 - 0.98 9.2 10.6 1.7 8.4 0.6 3.1 2 1 1 3 3 3 0 Putative manganese efflux pump Band_7 PF01145.25 GAN08293.1 - 4.7e-23 82.1 5.2 7.4e-23 81.5 5.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 GAN08293.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain Forkhead PF00250.18 GAN08294.1 - 2.5e-34 117.4 0.1 5.2e-34 116.4 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Pkinase PF00069.25 GAN08295.1 - 6.8e-72 242.0 0.0 1.1e-71 241.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08295.1 - 9.9e-27 93.8 0.1 3.8e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN08295.1 - 3.8e-10 39.5 0.0 0.065 12.5 0.0 3.3 3 0 0 3 3 3 3 Kinase-like Kelch_4 PF13418.6 GAN08295.1 - 8.9e-10 38.4 6.4 0.032 14.2 0.0 5.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN08295.1 - 2.9e-09 36.7 7.8 0.00032 20.6 0.0 4.9 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAN08295.1 - 3.3e-05 23.7 3.1 0.89 9.6 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 GAN08295.1 - 0.00034 20.8 13.1 3.2 8.2 0.0 5.8 6 1 0 6 6 6 3 Kelch motif Pkinase_fungal PF17667.1 GAN08295.1 - 0.0013 17.6 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kelch_3 PF13415.6 GAN08295.1 - 0.016 15.5 0.0 0.016 15.5 0.0 5.3 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF4256 PF14066.6 GAN08295.1 - 0.022 14.5 0.0 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) Myc_target_1 PF15179.6 GAN08295.1 - 0.046 13.6 1.9 0.34 10.8 1.9 2.2 1 1 0 1 1 1 0 Myc target protein 1 TMEM154 PF15102.6 GAN08295.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 GAN08295.1 - 0.084 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless APH PF01636.23 GAN08295.1 - 0.096 12.6 0.0 5.5 6.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4604 PF15377.6 GAN08296.1 - 7.1e-12 46.1 27.3 9.2e-12 45.7 27.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2944 PF11161.8 GAN08296.1 - 0.098 12.5 0.3 0.7 9.8 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) DUF966 PF06136.13 GAN08296.1 - 0.41 10.3 11.0 0.47 10.1 11.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) UPF0524 PF15823.5 GAN08296.1 - 3 7.2 6.7 0.61 9.4 3.1 1.7 1 1 1 2 2 2 0 UPF0524 of C3orf70 TPR_1 PF00515.28 GAN08297.1 - 2e-28 97.0 10.3 0.0012 18.6 0.1 10.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAN08297.1 - 2.5e-28 98.4 4.2 1.3e-07 32.0 0.3 7.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAN08297.1 - 7.3e-28 94.4 6.3 0.017 15.2 0.0 11.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAN08297.1 - 2.5e-20 70.9 10.8 0.0022 18.1 0.1 11.3 10 1 0 11 11 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAN08297.1 - 3.7e-18 64.5 7.2 0.0025 18.1 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAN08297.1 - 7.3e-18 64.6 9.1 1.2e-05 25.5 0.0 7.6 6 2 1 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAN08297.1 - 1.8e-16 58.8 4.7 0.0016 18.3 0.1 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAN08297.1 - 6e-16 58.8 6.7 0.00042 20.9 0.0 7.2 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAN08297.1 - 3.5e-15 55.5 10.6 1.1 10.1 0.0 10.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN08297.1 - 2.5e-14 52.8 7.2 0.15 13.0 0.1 9.9 5 2 5 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN08297.1 - 6.1e-13 48.2 11.1 0.0012 18.5 0.0 7.0 7 0 0 7 7 7 4 TPR repeat TPR_9 PF13371.6 GAN08297.1 - 5.2e-10 39.3 0.1 0.00016 21.7 0.0 5.0 3 2 3 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN08297.1 - 1e-07 32.0 5.9 0.54 10.5 0.0 6.0 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAN08297.1 - 7.2e-06 25.7 17.5 0.0012 18.6 0.1 8.1 10 0 0 10 10 10 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAN08297.1 - 2.6e-05 24.7 1.3 2.8 8.4 0.1 4.4 2 1 1 3 3 3 2 Alkyl sulfatase dimerisation TPR_20 PF14561.6 GAN08297.1 - 3.2e-05 24.2 7.9 0.46 10.8 1.1 5.8 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN08297.1 - 0.0036 16.7 4.7 0.57 9.5 0.5 4.1 4 0 0 4 4 4 1 MalT-like TPR region Vps39_1 PF10366.9 GAN08297.1 - 0.0076 16.5 7.1 1.3 9.3 0.4 4.2 3 1 1 4 4 4 2 Vacuolar sorting protein 39 domain 1 MIT PF04212.18 GAN08297.1 - 0.022 14.8 2.6 9.2 6.4 0.2 5.3 6 0 0 6 6 4 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 GAN08297.1 - 0.024 15.2 0.2 82 4.3 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAN08297.1 - 0.071 13.0 2.0 0.28 11.1 0.0 3.0 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal SesA PF17107.5 GAN08297.1 - 4.1 7.6 6.6 4.7 7.4 2.2 3.3 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Peptidase_M28 PF04389.17 GAN08298.1 - 2.5e-45 154.6 0.0 4.4e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAN08298.1 - 2.1e-05 24.3 0.0 3.4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 GAN08298.1 - 0.0021 17.2 0.0 0.0065 15.5 0.0 1.7 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase CobS PF02654.15 GAN08298.1 - 7.8 6.6 17.8 0.093 12.9 4.5 2.9 3 0 0 3 3 3 0 Cobalamin-5-phosphate synthase Mgm101p PF06420.12 GAN08299.1 - 7.3e-81 269.7 0.1 2.3e-78 261.6 0.1 2.3 1 1 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MGC-24 PF05283.11 GAN08299.1 - 0.82 10.1 5.0 1.4 9.4 5.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_transf_20 PF00982.21 GAN08300.1 - 8.5e-57 192.9 0.3 1.3e-56 192.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN08300.1 - 2.1e-12 46.7 0.0 4.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase APOBEC3 PF18771.1 GAN08300.1 - 0.021 14.9 1.7 5.1 7.2 0.1 3.1 3 0 0 3 3 3 0 APOBEC3 RecU PF03838.14 GAN08300.1 - 0.064 13.3 0.4 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Recombination protein U Peptidase_M24 PF00557.24 GAN08301.1 - 1.3e-54 185.1 0.1 1.6e-54 184.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GAN08301.1 - 8.7e-21 74.0 8.2 1.9e-20 72.9 8.2 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GAN08301.1 - 0.00012 22.0 5.2 0.00031 20.8 5.2 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 GAN08301.1 - 1.6 8.7 5.3 4.3 7.3 5.3 1.8 1 0 0 1 1 1 0 HIT zinc finger Peptidase_S8 PF00082.22 GAN08302.1 - 4.6e-39 134.5 7.4 7.2e-39 133.8 7.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAN08302.1 - 0.008 16.8 0.3 0.016 15.8 0.3 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pyridoxal_deC PF00282.19 GAN08303.1 - 1.3e-67 228.2 0.0 2.9e-67 227.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain IMPDH PF00478.25 GAN08304.1 - 5.9e-133 443.1 4.2 7.8e-133 442.7 4.2 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain RRM_1 PF00076.22 GAN08304.1 - 1.1e-23 82.8 5.4 9.8e-17 60.5 0.1 4.4 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.28 GAN08304.1 - 2.7e-16 59.7 0.3 3.3e-09 37.1 0.1 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 GAN08304.1 - 4.3e-09 35.9 1.3 1.9e-08 33.7 0.8 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 GAN08304.1 - 2.7e-06 27.0 5.0 0.00058 19.3 3.7 2.8 2 1 1 3 3 3 2 Nitronate monooxygenase RRM_7 PF16367.5 GAN08304.1 - 8.8e-06 25.8 0.0 0.00047 20.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif His_biosynth PF00977.21 GAN08304.1 - 1.4e-05 24.7 1.6 0.0021 17.6 0.1 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.14 GAN08304.1 - 0.00033 20.1 0.5 0.0013 18.1 0.1 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 GAN08304.1 - 0.0013 18.0 0.1 0.0029 16.8 0.1 1.6 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase RRM_Rrp7 PF17799.1 GAN08304.1 - 0.0064 16.3 0.4 2 8.2 0.0 3.9 3 2 2 5 5 5 1 Rrp7 RRM-like N-terminal domain PK PF00224.21 GAN08304.1 - 0.019 13.9 0.0 0.05 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Aldolase PF01081.19 GAN08304.1 - 0.028 13.8 0.0 0.085 12.3 0.0 1.8 1 0 0 1 1 1 0 KDPG and KHG aldolase B12-binding PF02310.19 GAN08304.1 - 0.036 14.1 0.0 0.36 10.9 0.0 2.5 3 0 0 3 3 3 0 B12 binding domain Nup35_RRM_2 PF14605.6 GAN08304.1 - 0.067 13.2 0.0 15 5.7 0.0 2.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif G3P_antiterm PF04309.12 GAN08304.1 - 0.09 12.2 0.2 10 5.5 0.0 2.6 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator YpsA PF06908.11 GAN08304.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 YspA SLOG family RT_RNaseH PF17917.1 GAN08305.1 - 1.6e-31 108.7 0.0 3.9e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN08305.1 - 2.2e-31 107.8 0.0 3.7e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GAN08305.1 - 5.8e-20 71.1 0.1 1e-19 70.4 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GAN08305.1 - 9.3e-10 38.7 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain ADH_zinc_N PF00107.26 GAN08306.1 - 1.4e-21 76.8 0.4 2.5e-21 76.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN08306.1 - 1.8e-09 38.7 0.0 3.8e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN08306.1 - 2.9e-07 30.4 0.0 7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAN08306.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 GAN08306.1 - 0.0038 16.5 0.4 0.0072 15.6 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 GAN08306.1 - 0.024 14.1 0.2 0.046 13.2 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KH_1 PF00013.29 GAN08307.1 - 1.6e-09 37.5 0.2 6e-06 26.0 0.0 2.8 2 1 0 2 2 2 2 KH domain GRP PF07172.11 GAN08307.1 - 0.0055 17.4 2.5 0.019 15.7 2.5 1.9 1 0 0 1 1 1 1 Glycine rich protein family ACOX PF01756.19 GAN08308.1 - 3.3e-49 166.9 0.0 6.5e-49 165.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAN08308.1 - 1.5e-19 70.0 0.0 2.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 GAN08308.1 - 2.9e-14 53.7 0.1 8.3e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 GAN08308.1 - 7.3e-09 36.0 0.8 9.8e-08 32.3 0.8 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Melibiase PF02065.18 GAN08310.1 - 2.3e-12 46.6 0.6 3.8e-12 45.8 0.6 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.26 GAN08310.1 - 6.6e-06 25.6 0.2 1.3e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GHL15 PF14885.6 GAN08310.1 - 0.03 14.3 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 GHL6 PF14871.6 GAN08310.1 - 0.08 13.1 0.0 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Ubie_methyltran PF01209.18 GAN08311.1 - 9.2e-67 224.8 0.3 2.1e-42 145.0 0.1 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAN08311.1 - 5.3e-11 43.1 0.1 1.3e-10 41.9 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN08311.1 - 5.2e-09 36.7 0.1 1.3e-08 35.4 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08311.1 - 8.1e-07 28.9 0.1 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN08311.1 - 1.6e-05 25.5 0.6 5.8e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.17 GAN08311.1 - 0.017 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SURF1 PF02104.15 GAN08312.1 - 3.1e-46 157.8 0.0 4.2e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family RRM_1 PF00076.22 GAN08313.1 - 9.7e-22 76.6 0.3 1.6e-21 75.8 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 GAN08313.1 - 0.038 13.8 0.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain NifU_N PF01592.16 GAN08314.1 - 3.1e-55 185.8 0.1 3.7e-55 185.6 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Cyclin_N PF00134.23 GAN08315.1 - 1.8e-10 40.6 0.0 2.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN08315.1 - 2.2e-06 28.2 0.1 3.5e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 Cyclin ThiF PF00899.21 GAN08316.1 - 2.4e-54 184.3 0.0 3.5e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 GAN08316.1 - 0.0021 18.6 0.1 0.0054 17.2 0.1 1.8 1 0 0 1 1 1 1 Rhodanese-like domain bZIP_2 PF07716.15 GAN08316.1 - 0.059 13.5 0.7 0.059 13.5 0.7 2.7 3 0 0 3 3 3 0 Basic region leucine zipper MARVEL PF01284.23 GAN08317.1 - 5.8e-11 42.6 11.8 8.9e-11 42.0 11.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 GAN08317.1 - 0.00033 20.5 7.5 0.0017 18.2 7.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF588) SCIMP PF15050.6 GAN08317.1 - 6.5 7.2 7.4 2.3 8.7 1.6 2.3 2 0 0 2 2 2 0 SCIMP protein CH PF00307.31 GAN08318.1 - 3.8e-84 278.1 0.3 1.3e-19 70.4 0.0 4.4 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAN08318.1 - 3e-08 33.4 0.0 0.048 13.5 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 GAN08318.1 - 8.4e-08 32.6 0.1 4.9e-07 30.1 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAN08318.1 - 2.3e-05 23.6 0.2 0.51 10.0 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAN08318.1 - 0.00025 20.7 0.3 1.1 9.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GAN08318.1 - 0.001 18.5 0.1 0.25 10.9 0.0 3.0 2 0 0 2 2 2 1 EF hand CH_2 PF06294.11 GAN08318.1 - 0.016 15.3 0.1 15 5.8 0.0 3.7 3 0 0 3 3 3 0 CH-like domain in sperm protein RNB PF00773.19 GAN08318.1 - 0.094 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 RNB domain EF-hand_8 PF13833.6 GAN08318.1 - 0.12 12.3 0.1 0.56 10.1 0.1 2.3 1 1 0 1 1 1 0 EF-hand domain pair Trm112p PF03966.16 GAN08319.1 - 3.6e-20 72.3 0.1 4.2e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Transpos_assoc PF13963.6 GAN08319.1 - 0.0015 18.8 0.2 0.066 13.5 0.1 2.1 2 0 0 2 2 2 1 Transposase-associated domain His_kinase PF06580.13 GAN08319.1 - 0.0017 18.6 0.2 0.0033 17.7 0.2 1.6 1 1 0 1 1 1 1 Histidine kinase PhnA_Zn_Ribbon PF08274.12 GAN08319.1 - 0.038 13.9 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 GAN08319.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain MOZART1 PF12554.8 GAN08319.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated RNF220 PF15926.5 GAN08320.1 - 1.3e-33 116.7 18.1 5.3e-33 114.7 18.1 2.0 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 GAN08320.1 - 6.3e-11 41.9 12.1 6.3e-11 41.9 12.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN08320.1 - 6.2e-05 22.8 16.9 0.00022 21.0 8.9 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN08320.1 - 7.3e-05 22.5 14.7 0.018 14.9 8.5 3.4 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAN08320.1 - 0.0008 19.2 12.0 0.0008 19.2 12.0 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN08320.1 - 0.0024 18.1 12.3 0.0024 18.1 12.3 3.5 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 GAN08320.1 - 0.0056 16.6 10.2 0.0056 16.6 10.2 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-Nse PF11789.8 GAN08320.1 - 4 7.3 10.0 0.59 10.0 5.0 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 GAN08320.1 - 4.3 7.5 13.8 52 4.0 0.2 3.7 3 1 0 3 3 3 0 Double zinc ribbon CTD_bind PF04818.13 GAN08321.1 - 4.6e-09 37.0 0.0 1.3e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DNA_RNApol_7kD PF03604.13 GAN08321.1 - 0.02 14.5 0.1 0.094 12.4 0.0 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit CFIA_Pcf11 PF11526.8 GAN08321.1 - 0.022 15.2 0.7 0.067 13.7 0.0 2.1 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Synaptobrevin PF00957.21 GAN08322.1 - 1.5e-31 108.0 1.2 2e-31 107.6 1.2 1.1 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 GAN08322.1 - 0.018 14.6 0.7 0.018 14.6 0.7 2.1 1 1 1 2 2 2 0 fzo-like conserved region Glyoxalase_3 PF13468.6 GAN08322.1 - 0.027 14.6 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain MCU PF04678.13 GAN08322.1 - 0.036 14.2 0.2 0.04 14.0 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF5345 PF17280.2 GAN08322.1 - 0.23 11.4 0.0 0.23 11.4 0.0 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5345) ETRAMP PF09716.10 GAN08322.1 - 0.25 11.4 1.7 0.79 9.8 0.4 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ferlin_C PF16165.5 GAN08322.1 - 0.93 9.4 4.7 0.91 9.5 3.1 1.6 1 1 1 2 2 2 0 Ferlin C-terminus EF-hand_1 PF00036.32 GAN08323.1 - 1.3e-42 140.1 10.9 3.4e-10 38.7 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN08323.1 - 7.1e-36 122.5 3.0 3.4e-19 69.1 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAN08323.1 - 5.3e-33 112.6 10.9 2.8e-15 55.9 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAN08323.1 - 1.1e-31 106.0 7.8 1.9e-09 36.7 0.0 4.6 4 2 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 GAN08323.1 - 1.9e-27 93.5 9.0 1.4e-06 27.5 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAN08323.1 - 7.6e-14 51.8 0.1 1.9e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAN08323.1 - 3.7e-10 39.7 0.9 0.00023 21.1 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN08323.1 - 4.8e-10 39.8 0.4 0.00017 21.9 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 GAN08323.1 - 2.3e-06 28.4 0.1 5.4e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 GAN08323.1 - 1.4e-05 25.1 1.6 0.00024 21.1 0.2 2.5 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 GAN08323.1 - 9.2e-05 22.6 3.7 0.043 14.0 0.2 3.1 1 1 1 2 2 2 2 Dockerin type I domain DUF3349 PF11829.8 GAN08323.1 - 0.00021 22.0 0.6 3.8 8.4 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 GAN08323.1 - 0.00022 21.2 1.0 1.3 8.9 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 GAN08323.1 - 0.00041 20.3 1.5 0.17 11.9 0.3 2.6 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF5580 PF17743.1 GAN08323.1 - 0.0024 16.5 0.0 0.0027 16.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF2267 PF10025.9 GAN08323.1 - 0.0028 17.9 0.0 0.026 14.8 0.0 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) RNA_pol_Rpb4 PF03874.16 GAN08323.1 - 0.0055 17.0 2.7 0.93 9.8 0.2 3.1 2 1 1 3 3 3 1 RNA polymerase Rpb4 UPF0154 PF03672.13 GAN08323.1 - 0.008 16.2 0.0 0.35 10.9 0.0 2.7 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF1103 PF06513.11 GAN08323.1 - 0.0082 15.8 1.3 0.0098 15.5 1.3 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 GAN08323.1 - 0.012 15.4 1.2 0.88 9.4 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 GAN08323.1 - 0.014 15.1 0.7 0.054 13.1 0.7 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF4497 PF14924.6 GAN08323.1 - 0.015 15.8 0.0 0.15 12.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) DUF853 PF05872.12 GAN08323.1 - 0.041 12.5 0.1 0.28 9.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Spore_III_AB PF09548.10 GAN08323.1 - 0.051 13.7 0.6 0.088 12.9 0.6 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) MotA_activ PF09114.10 GAN08323.1 - 0.055 13.6 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RPN13_C PF16550.5 GAN08323.1 - 0.057 13.6 0.0 2.3 8.4 0.0 2.3 2 1 0 2 2 2 0 UCH-binding domain p25-alpha PF05517.12 GAN08323.1 - 0.061 13.5 0.6 12 6.1 0.2 2.3 1 1 1 2 2 2 0 p25-alpha PhageMin_Tail PF10145.9 GAN08323.1 - 0.094 12.6 1.2 0.11 12.3 0.5 1.5 2 0 0 2 2 2 0 Phage-related minor tail protein DUF1811 PF08838.10 GAN08323.1 - 0.1 12.9 0.4 19 5.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1811) CMD PF02627.20 GAN08323.1 - 0.26 11.4 0.8 2.6 8.2 0.0 2.7 3 1 1 4 4 3 0 Carboxymuconolactone decarboxylase family PPR_1 PF12854.7 GAN08323.1 - 0.99 9.2 3.6 58 3.5 0.1 3.4 3 0 0 3 3 3 0 PPR repeat Vps35 PF03635.17 GAN08324.1 - 7.4e-263 874.4 25.1 8.5e-263 874.2 25.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Presenilin PF01080.17 GAN08324.1 - 0.13 11.0 4.7 0.23 10.2 4.7 1.3 1 0 0 1 1 1 0 Presenilin Mad3_BUB1_I PF08311.12 GAN08325.1 - 1.1e-38 132.0 3.5 1.1e-38 132.0 3.5 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 GAN08325.1 - 4.4e-05 23.6 1.3 9e-05 22.6 1.3 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein TPR_14 PF13428.6 GAN08325.1 - 0.82 10.7 3.5 3.2 8.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FHA PF00498.26 GAN08326.1 - 3.8e-07 30.4 0.1 1.1e-06 28.8 0.1 1.9 2 0 0 2 2 2 1 FHA domain FHA_2 PF17913.1 GAN08326.1 - 0.00018 21.7 0.6 0.00043 20.5 0.0 2.0 2 0 0 2 2 2 1 FHA domain RNA_pol_Rpc4 PF05132.14 GAN08326.1 - 0.025 15.0 0.4 0.025 15.0 0.4 2.7 3 0 0 3 3 3 0 RNA polymerase III RPC4 GxGYxYP_C PF14323.6 GAN08326.1 - 2.8 7.7 6.3 2.4 7.9 1.5 2.3 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain LAG1-DNAbind PF09271.11 GAN08328.1 - 6.8e-23 82.0 3.0 6.8e-23 82.0 3.0 3.5 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 GAN08328.1 - 1.3e-21 77.4 0.1 3.2e-09 37.2 0.0 2.8 2 0 0 2 2 2 2 Beta-trefoil DNA-binding domain SLM4 PF16818.5 GAN08328.1 - 0.67 9.9 17.2 0.026 14.5 9.4 2.2 2 0 0 2 2 2 0 Protein SLM4 Chitin_synth_1 PF01644.17 GAN08329.1 - 8.1e-80 266.5 0.1 1.4e-79 265.8 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase SNAP PF14938.6 GAN08329.1 - 6.4e-31 107.8 18.0 9.9e-31 107.2 18.0 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Chitin_synth_1N PF08407.11 GAN08329.1 - 5.3e-30 103.2 0.1 2.9e-29 100.8 0.1 2.4 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAN08329.1 - 9e-25 87.3 2.0 2.1e-19 69.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN08329.1 - 2.8e-05 24.1 8.1 0.00028 20.9 8.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 TOM20_plant PF06552.12 GAN08329.1 - 0.34 10.6 2.3 0.43 10.3 0.9 1.9 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_14 PF13428.6 GAN08329.1 - 0.54 11.2 9.7 17 6.6 0.4 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN08329.1 - 5.2 7.4 14.3 1.6 9.1 6.5 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN08329.1 - 7.4 6.6 14.9 32 4.6 0.1 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 GAN08329.1 - 8.6 6.5 17.5 9.3 6.4 0.5 5.0 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain Glyco_hydro_9 PF00759.19 GAN08330.1 - 4.9e-95 319.4 22.4 4.9e-95 319.4 22.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 Mitofilin PF09731.9 GAN08330.1 - 0.055 12.3 7.4 0.081 11.8 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PE PF00934.20 GAN08330.1 - 0.057 13.8 5.1 0.16 12.3 5.1 1.7 1 0 0 1 1 1 0 PE family DUF908 PF06012.12 GAN08330.1 - 0.077 12.4 11.1 0.13 11.6 11.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 GAN08330.1 - 0.26 10.0 0.5 0.4 9.4 0.5 1.2 1 0 0 1 1 1 0 Presenilin CENP-U PF13097.6 GAN08330.1 - 7.3 6.5 11.1 74 3.2 11.5 2.1 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit IBR PF01485.21 GAN08331.1 - 4.5e-08 33.2 29.5 6.1e-06 26.4 6.2 4.3 2 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 GAN08331.1 - 0.0076 16.6 9.3 0.0076 16.6 9.3 4.0 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 GAN08331.1 - 0.017 15.0 10.2 0.017 15.0 10.2 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN08331.1 - 0.033 14.0 5.3 0.033 14.0 5.3 3.9 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) XPG_I PF00867.18 GAN08332.1 - 2e-20 72.9 0.3 5e-20 71.6 0.3 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAN08332.1 - 1.8e-18 66.8 0.0 3.7e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 GAN08332.1 - 2.3e-05 24.0 0.8 9.8e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 XPG domain containing TPR_1 PF00515.28 GAN08332.1 - 0.016 15.0 0.2 0.049 13.5 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5616 PF18481.1 GAN08332.1 - 0.021 15.2 1.9 0.32 11.3 0.2 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5616) Syntaxin-18_N PF10496.9 GAN08332.1 - 0.032 14.5 0.3 0.032 14.5 0.3 2.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus TPR_2 PF07719.17 GAN08332.1 - 0.056 13.6 1.6 0.071 13.3 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PIN_9 PF18477.1 GAN08332.1 - 0.16 12.3 0.5 0.44 10.9 0.3 1.7 1 1 0 1 1 1 0 PIN like domain HemY_N PF07219.13 GAN08332.1 - 0.18 12.0 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 HemY protein N-terminus TPR_8 PF13181.6 GAN08332.1 - 0.61 10.4 1.9 0.96 9.8 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 GAN08333.1 - 0.0025 18.2 0.3 0.0083 16.5 0.3 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain KOG2701 PF09762.9 GAN08333.1 - 0.38 11.0 3.9 0.73 10.0 0.0 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein (DUF2037) TFIIA PF03153.13 GAN08333.1 - 0.71 9.8 15.1 1 9.3 15.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1161 PF06649.12 GAN08334.1 - 0.019 15.2 0.2 0.039 14.2 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1161) PRP3 PF08572.10 GAN08335.1 - 6e-73 245.3 9.5 1.4e-72 244.1 9.5 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 GAN08335.1 - 1.1e-44 152.0 0.2 2.6e-44 150.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) FliX PF10768.9 GAN08335.1 - 0.017 15.6 2.8 0.052 14.1 2.8 1.9 1 0 0 1 1 1 0 Class II flagellar assembly regulator FlaG PF03646.15 GAN08335.1 - 3.8 7.7 8.5 18 5.6 0.3 2.7 2 0 0 2 2 2 0 FlaG protein Ribosomal_L44 PF00935.19 GAN08336.1 - 4.5e-38 129.6 10.1 6.6e-38 129.1 10.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 UQ_con PF00179.26 GAN08337.1 - 2.2e-48 163.4 0.0 2.5e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAN08337.1 - 0.0037 17.0 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAN08337.1 - 0.062 13.6 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain BRE PF06113.12 GAN08337.1 - 0.076 11.9 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Ras PF00071.22 GAN08338.1 - 5.7e-43 146.3 4.1 1e-41 142.2 4.1 2.3 1 1 0 1 1 1 1 Ras family Chromo PF00385.24 GAN08338.1 - 7.7e-12 44.9 0.4 1.7e-11 43.8 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Roc PF08477.13 GAN08338.1 - 6.4e-11 42.5 3.1 4.8e-09 36.5 0.8 3.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAN08338.1 - 0.0023 17.5 0.4 0.005 16.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 GAN08338.1 - 0.015 14.8 0.7 0.041 13.3 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF1394 PF07159.12 GAN08339.1 - 1.6e-108 362.5 0.0 1.9e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Aldo_ket_red PF00248.21 GAN08340.1 - 3.9e-55 187.1 0.1 2.7e-53 181.1 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family nos_propeller_2 PF18793.1 GAN08340.1 - 0.13 12.6 0.0 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat 2 BetR PF08667.10 GAN08340.1 - 0.17 11.9 0.0 21 5.1 0.0 2.2 2 0 0 2 2 2 0 BetR domain tRNA_lig_CPD PF08302.11 GAN08341.1 - 0.024 14.1 0.2 0.032 13.7 0.2 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain RNase_H PF00075.24 GAN08343.1 - 2.5e-38 131.5 0.1 3.6e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 GAN08343.1 - 4.6e-21 74.9 1.3 1.1e-20 73.7 1.3 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 GAN08343.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like Proteasome PF00227.26 GAN08344.1 - 2.9e-52 176.9 0.1 3.9e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 GAN08344.1 - 2.9e-13 49.0 0.1 2.9e-13 49.0 0.1 2.0 2 0 0 2 2 2 1 Proteasome beta subunits C terminal SRR1 PF07985.12 GAN08345.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 SRR1 DUF5474 PF17568.2 GAN08345.1 - 0.014 15.5 0.0 0.043 13.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5474) RRP7 PF12923.7 GAN08346.1 - 0.014 15.5 3.3 0.016 15.3 3.3 1.3 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PRK PF00485.18 GAN08346.1 - 0.083 12.6 0.4 0.093 12.5 0.4 1.0 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF3512 PF12024.8 GAN08347.1 - 0.011 15.3 2.2 0.014 14.9 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3512) Bromodomain PF00439.25 GAN08347.1 - 0.018 15.1 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Bromodomain tRNA-synt_1e PF01406.19 GAN08347.1 - 0.16 11.3 2.9 0.19 11.0 0.3 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 GAN08348.1 - 3.4e-70 236.4 0.1 4.4e-70 236.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08348.1 - 1.3e-36 126.2 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN08348.1 - 3.2e-05 23.4 0.0 8.9e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAN08348.1 - 0.00018 20.4 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 GAN08348.1 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain ABC1 PF03109.16 GAN08348.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Kdo PF06293.14 GAN08348.1 - 0.018 14.4 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OGG_N PF07934.12 GAN08349.1 - 1.8e-27 95.8 0.7 5.5e-27 94.2 0.3 2.1 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 GAN08349.1 - 1.1e-15 58.1 0.0 1.9e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAN08349.1 - 0.0028 17.5 0.0 0.0062 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif AKAP7_NLS PF10469.9 GAN08349.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain DUF1827 PF08860.10 GAN08349.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) Septin PF00735.18 GAN08351.1 - 1.5e-115 385.3 0.6 1.5e-115 385.3 0.6 2.0 3 0 0 3 3 3 1 Septin MMR_HSR1 PF01926.23 GAN08351.1 - 9.9e-08 32.1 0.2 3.3e-07 30.4 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN08351.1 - 2.3e-06 27.6 7.1 6e-06 26.3 0.2 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 GAN08351.1 - 8.3e-05 22.2 1.6 0.003 17.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 GAN08351.1 - 0.0061 15.9 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 GAN08351.1 - 0.03 13.9 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Ras family Roc PF08477.13 GAN08351.1 - 0.07 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAN08351.1 - 0.072 13.4 0.8 0.21 11.9 0.0 2.2 2 2 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.11 GAN08351.1 - 0.085 12.9 0.4 0.085 12.9 0.4 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_14 PF13173.6 GAN08351.1 - 0.085 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAN08351.1 - 0.094 13.2 3.6 0.38 11.3 0.1 2.6 2 1 0 2 2 2 0 ABC transporter Exonuc_VII_L PF02601.15 GAN08351.1 - 0.1 12.1 5.6 0.18 11.4 5.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_29 PF13555.6 GAN08351.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 GAN08351.1 - 0.3 11.1 5.8 9.7 6.2 0.0 3.4 2 2 1 3 3 3 0 Dynamin family Atg14 PF10186.9 GAN08351.1 - 0.48 9.5 5.1 0.83 8.7 5.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MraZ PF02381.18 GAN08352.1 - 0.0037 17.2 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 MraZ protein, putative antitoxin-like BLOC1_2 PF10046.9 GAN08352.1 - 0.0059 16.9 1.3 2.3 8.6 0.1 2.2 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med30 PF11315.8 GAN08352.1 - 0.01 16.0 2.1 0.72 10.1 2.1 2.0 1 1 0 1 1 1 0 Mediator complex subunit 30 Syntaxin-6_N PF09177.11 GAN08352.1 - 0.012 16.2 1.1 0.019 15.5 1.1 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal YabA PF06156.13 GAN08352.1 - 0.013 16.1 1.4 0.91 10.2 0.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Lge1 PF11488.8 GAN08352.1 - 0.014 15.5 2.2 0.44 10.8 0.2 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 V-SNARE PF05008.15 GAN08352.1 - 0.015 15.7 1.4 0.47 10.9 0.2 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CLZ PF16526.5 GAN08352.1 - 0.021 15.1 1.0 3.8 7.9 0.1 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2205 PF10224.9 GAN08352.1 - 0.028 14.4 1.1 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Short coiled-coil protein Tup_N PF08581.10 GAN08352.1 - 0.031 14.6 1.4 0.11 12.8 0.2 2.0 2 0 0 2 2 2 0 Tup N-terminal DASH_Dad3 PF08656.10 GAN08352.1 - 0.054 13.6 2.8 0.24 11.5 0.1 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 COG5 PF10392.9 GAN08352.1 - 0.058 13.6 3.7 6.2 7.0 0.5 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 DASH_Dad4 PF08650.10 GAN08352.1 - 0.076 13.0 0.4 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad4 FliD_N PF02465.18 GAN08352.1 - 0.16 12.7 5.7 8.8 7.1 5.7 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DivIC PF04977.15 GAN08352.1 - 0.21 11.4 4.0 3.5 7.5 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator AAA_12 PF13087.6 GAN08354.1 - 4.7e-48 163.4 0.0 8.8e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAN08354.1 - 1.5e-28 100.3 0.1 8.3e-19 68.4 0.0 3.0 2 1 1 3 3 3 2 AAA domain DUF2439 PF10382.9 GAN08354.1 - 1.2e-15 57.6 0.1 3.4e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.18 GAN08354.1 - 6.8e-11 42.4 0.0 0.0011 18.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GAN08354.1 - 1.7e-05 25.1 0.0 5.9e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 GAN08354.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 GAN08354.1 - 0.0006 19.6 0.0 0.013 15.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain PIF1 PF05970.14 GAN08354.1 - 0.039 13.1 0.0 0.34 10.0 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase Cucumopine_C PF18631.1 GAN08354.1 - 0.14 12.1 0.1 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain Torsin PF06309.11 GAN08354.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF262 PF03235.14 GAN08355.1 - 1.1e-13 51.8 10.3 1.3e-12 48.4 5.6 2.9 2 2 0 2 2 2 1 Protein of unknown function DUF262 Val_tRNA-synt_C PF10458.9 GAN08356.1 - 0.027 14.8 0.9 4.8 7.5 1.0 2.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF1664 PF07889.12 GAN08356.1 - 0.14 12.2 2.8 0.72 9.9 1.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) KCNQ2_u3 PF16642.5 GAN08356.1 - 0.32 12.0 7.0 0.089 13.8 2.3 2.1 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 GPS2_interact PF15784.5 GAN08356.1 - 0.32 11.5 7.9 0.49 10.9 5.9 2.1 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain ATF7IP_BD PF16788.5 GAN08356.1 - 0.49 10.5 10.2 0.068 13.3 0.7 2.2 2 0 0 2 2 2 0 ATF-interacting protein binding domain TFIIA PF03153.13 GAN08356.1 - 0.99 9.3 10.0 1.4 8.9 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.11 GAN08356.1 - 1 9.6 14.3 0.55 10.4 5.6 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spt20 PF12090.8 GAN08356.1 - 1.2 8.7 15.3 2.1 7.9 4.1 2.1 2 0 0 2 2 2 0 Spt20 family DivIVA PF05103.13 GAN08356.1 - 1.4 9.0 11.5 0.091 12.9 2.5 2.3 2 0 0 2 2 2 0 DivIVA protein End3 PF12761.7 GAN08356.1 - 1.4 9.1 11.7 0.31 11.2 2.6 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 YabA PF06156.13 GAN08356.1 - 1.9 9.2 8.1 17 6.1 0.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DASH_Spc19 PF08287.11 GAN08356.1 - 2 8.3 10.8 0.068 13.1 2.2 2.0 2 0 0 2 2 2 0 Spc19 PRKG1_interact PF15898.5 GAN08356.1 - 2.2 9.2 12.1 9.4 7.2 3.3 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Fmp27_WPPW PF10359.9 GAN08356.1 - 2.5 6.9 8.8 0.34 9.7 3.7 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FAM76 PF16046.5 GAN08356.1 - 3 7.1 11.1 5.3 6.3 11.0 1.5 1 1 0 1 1 1 0 FAM76 protein Cep57_CLD PF14073.6 GAN08356.1 - 3 7.8 13.0 0.78 9.7 9.4 1.8 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 ZapB PF06005.12 GAN08356.1 - 3.3 8.2 9.9 2.2 8.8 6.1 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Fez1 PF06818.15 GAN08356.1 - 6 7.3 11.2 11 6.4 4.7 2.1 1 1 1 2 2 2 0 Fez1 APG17 PF04108.12 GAN08358.1 - 5.4e-67 226.6 16.5 6.9e-67 226.3 16.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Tannase PF07519.11 GAN08358.1 - 0.062 12.2 1.0 0.11 11.4 1.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Nup54 PF13874.6 GAN08358.1 - 0.29 11.2 5.3 3.1 7.9 1.5 3.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Orthopox_F14 PF06076.12 GAN08358.1 - 0.71 10.2 5.7 9.4 6.6 0.1 3.2 2 1 0 3 3 3 0 Orthopoxvirus F14 protein Holin_BhlA PF10960.8 GAN08358.1 - 2.5 8.1 19.7 9.7 6.2 0.6 5.0 5 0 0 5 5 5 0 BhlA holin family MinE PF03776.14 GAN08358.1 - 6.3 6.9 11.7 3.4 7.7 0.1 4.3 4 1 0 4 4 4 0 Septum formation topological specificity factor MinE CheY-binding PF09078.11 GAN08359.1 - 0.031 14.4 0.1 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 CheY binding COX14 PF14880.6 GAN08359.1 - 0.073 12.9 1.6 0.1 12.4 1.6 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c assembly Snf7 PF03357.21 GAN08360.1 - 4.5e-53 179.4 14.9 4.5e-53 179.4 14.9 1.8 2 0 0 2 2 2 1 Snf7 DASH_Dad4 PF08650.10 GAN08360.1 - 0.057 13.4 1.6 0.057 13.4 1.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 LCD1 PF09798.9 GAN08360.1 - 0.63 8.5 7.6 0.78 8.2 7.6 1.3 1 1 0 1 1 1 0 DNA damage checkpoint protein DAGK_cat PF00781.24 GAN08361.1 - 1.9e-28 98.6 0.0 5.9e-28 97.0 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain PAD PF03068.15 GAN08361.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) RrnaAD PF00398.20 GAN08362.1 - 1e-66 224.7 0.1 1.3e-66 224.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAN08362.1 - 1.8e-06 28.6 0.0 3.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAN08362.1 - 0.00017 21.4 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 GAN08362.1 - 0.00049 20.7 0.0 0.0009 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN08362.1 - 0.0019 18.9 0.0 0.0036 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN08362.1 - 0.0025 17.4 0.1 0.0069 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_28 PF02636.17 GAN08362.1 - 0.004 16.8 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 GAN08362.1 - 0.0055 16.0 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 GAN08362.1 - 0.0084 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 GAN08362.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 GAN08362.1 - 0.048 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 GAN08362.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DREV PF05219.12 GAN08362.1 - 0.077 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_2 PF00891.18 GAN08362.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 GAN08362.1 - 0.1 12.4 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PRMT5 PF05185.16 GAN08362.1 - 0.12 12.2 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Tfb2 PF03849.14 GAN08363.1 - 0.013 14.5 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 GCV_H PF01597.19 GAN08363.1 - 0.094 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein IIGP PF05049.13 GAN08364.1 - 4.9e-32 111.4 0.6 6.8e-32 110.9 0.6 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 GAN08364.1 - 5.6e-09 36.1 0.1 2.3e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN08364.1 - 9.2e-05 22.0 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 GAN08364.1 - 0.00035 20.8 0.3 0.0015 18.7 0.0 2.2 3 1 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAN08364.1 - 0.00059 19.8 1.0 0.0037 17.2 0.0 2.5 1 1 2 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 GAN08364.1 - 0.0016 18.9 4.9 0.018 15.6 4.9 2.2 1 1 0 1 1 1 1 ABC transporter AIG1 PF04548.16 GAN08364.1 - 0.0027 17.1 0.2 0.0063 15.9 0.0 1.7 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 GAN08364.1 - 0.04 14.2 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAN08364.1 - 0.048 13.7 6.2 0.2 11.7 0.3 3.0 2 1 1 3 3 3 0 Dynamin family AAA_29 PF13555.6 GAN08364.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAN08364.1 - 0.17 12.3 0.2 0.27 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 GAN08364.1 - 0.3 11.3 1.4 0.44 10.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAN08364.1 - 7.1 7.1 14.0 76 3.7 14.0 2.1 1 1 0 1 1 1 0 AAA domain CsbD PF05532.12 GAN08365.1 - 7.8e-15 54.5 19.7 3.9e-10 39.5 4.8 2.0 1 1 1 2 2 2 2 CsbD-like FAM70 PF14967.6 GAN08366.1 - 6.4 6.1 7.5 0.94 8.9 2.1 2.2 2 0 0 2 2 2 0 FAM70 protein zf-RING_2 PF13639.6 GAN08367.1 - 5.5e-14 52.2 5.2 1.2e-13 51.2 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAN08367.1 - 1.7e-10 40.5 1.4 1.7e-10 40.5 1.4 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAN08367.1 - 7.8e-09 35.2 5.9 1.4e-08 34.4 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN08367.1 - 1.4e-08 34.5 5.3 2.8e-08 33.5 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN08367.1 - 5.4e-07 29.8 8.6 3.7e-06 27.1 8.6 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN08367.1 - 1.3e-06 28.3 4.1 2.2e-06 27.5 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN08367.1 - 7.9e-06 25.6 5.9 1.7e-05 24.6 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN08367.1 - 1e-05 25.5 5.2 0.00012 22.0 0.9 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAN08367.1 - 9.5e-05 22.2 6.4 0.00023 21.0 6.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PA PF02225.22 GAN08367.1 - 0.0002 21.3 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-ANAPC11 PF12861.7 GAN08367.1 - 0.00037 20.5 4.9 0.0013 18.7 4.9 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAN08367.1 - 0.00079 19.2 3.9 0.0016 18.2 3.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.7 GAN08367.1 - 0.023 14.8 3.3 0.069 13.3 3.3 1.9 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 GAN08367.1 - 0.052 13.5 4.1 0.11 12.5 4.1 1.6 1 0 0 1 1 1 0 PHD-finger UPF0542 PF15086.6 GAN08367.1 - 0.086 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 zf-C3H2C3 PF17122.5 GAN08367.1 - 0.098 12.7 4.0 0.4 10.8 4.0 2.0 1 1 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 GAN08367.1 - 0.14 11.8 4.3 0.3 10.7 4.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 GAN08367.1 - 0.26 11.5 8.6 3.1 8.0 8.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 GAN08367.1 - 0.29 11.5 3.8 0.61 10.4 3.8 1.6 1 1 0 1 1 1 0 RING-like domain Pkinase PF00069.25 GAN08368.1 - 1e-59 202.0 0.0 2.3e-59 200.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08368.1 - 1e-33 116.7 0.0 1.3e-32 113.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN08368.1 - 5.6e-10 39.0 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN08368.1 - 9.6e-05 21.3 5.1 0.0002 20.3 0.2 2.4 2 0 0 2 2 2 1 Fungal protein kinase Exo70 PF03081.15 GAN08368.1 - 0.036 13.1 0.8 0.053 12.6 0.8 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit APH PF01636.23 GAN08368.1 - 0.057 13.3 0.3 0.7 9.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family E1_dh PF00676.20 GAN08369.1 - 5.7e-62 209.3 0.0 7.9e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 GAN08369.1 - 1.8e-61 206.9 0.0 3.4e-61 206.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GAN08369.1 - 9.5e-56 187.7 0.1 1.5e-55 187.0 0.1 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GAN08369.1 - 6.4e-20 70.5 0.4 1.5e-19 69.3 0.4 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus NSP2-B_epitope PF14757.6 GAN08369.1 - 0.095 12.4 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein SKG6 PF08693.10 GAN08370.1 - 0.0026 17.1 0.5 0.007 15.8 0.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DLIC PF05783.11 GAN08370.1 - 0.011 14.6 2.2 0.017 14.0 2.2 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) UPF0506 PF11703.8 GAN08370.1 - 0.02 15.2 8.1 0.041 14.3 8.1 1.5 1 0 0 1 1 1 0 UPF0506 Toxin_29 PF08116.11 GAN08370.1 - 0.026 14.5 2.2 0.08 13.0 2.2 1.8 1 0 0 1 1 1 0 PhTx neurotoxin family Dickkopf_N PF04706.12 GAN08370.1 - 0.033 14.7 9.7 0.07 13.6 9.7 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF2615 PF11027.8 GAN08370.1 - 0.034 14.3 7.5 0.05 13.7 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) PDCD2_C PF04194.13 GAN08370.1 - 0.046 13.8 3.6 0.081 13.0 3.6 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Adeno_E3_CR2 PF02439.15 GAN08370.1 - 0.07 12.9 1.3 0.1 12.4 1.3 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM190 PF15431.6 GAN08370.1 - 0.086 13.0 2.2 0.16 12.2 1.8 1.7 1 1 1 2 2 2 0 Transmembrane protein 190 She9_MDM33 PF05546.11 GAN08370.1 - 0.13 12.1 2.2 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 She9 / Mdm33 family EphA2_TM PF14575.6 GAN08370.1 - 0.15 13.0 1.7 0.41 11.6 1.7 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Nitrate_red_gam PF02665.14 GAN08370.1 - 0.16 11.5 0.1 0.27 10.7 0.1 1.3 1 1 0 1 1 1 0 Nitrate reductase gamma subunit Miga PF10265.9 GAN08370.1 - 0.22 10.5 6.2 0.29 10.1 6.2 1.2 1 0 0 1 1 1 0 Mitoguardin EB PF01683.18 GAN08370.1 - 0.3 11.4 12.4 0.42 10.9 10.3 2.2 2 1 1 3 3 2 0 EB module TMEM154 PF15102.6 GAN08370.1 - 0.38 10.6 0.0 0.38 10.6 0.0 2.5 1 1 1 2 2 2 0 TMEM154 protein family MIS13 PF08202.11 GAN08374.1 - 4.7e-12 45.8 6.9 8.9e-12 44.9 6.9 1.4 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Elongin_A PF06881.11 GAN08374.1 - 0.0098 16.4 2.1 0.033 14.7 0.1 2.3 1 1 1 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2791 PF10923.8 GAN08374.1 - 0.016 14.1 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Fib_alpha PF08702.10 GAN08374.1 - 0.13 12.4 5.7 4.1 7.6 0.1 2.9 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Exo_endo_phos PF03372.23 GAN08375.1 - 5.7e-06 26.0 0.5 1.4e-05 24.7 0.5 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CCDC53 PF10152.9 GAN08376.1 - 0.096 13.1 0.7 0.57 10.6 0.1 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Aa_trans PF01490.18 GAN08377.1 - 1.2e-77 261.3 32.0 1.4e-77 261.2 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAN08377.1 - 0.2 10.6 27.3 0.02 13.9 18.1 3.1 1 1 0 2 2 2 0 Tryptophan/tyrosine permease family DASH_Dad2 PF08654.10 GAN08378.1 - 5.4 7.5 9.2 2.6 8.5 0.3 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad2 CLASP_N PF12348.8 GAN08379.1 - 4.1e-27 95.2 0.1 7.4e-07 29.0 0.1 6.0 5 1 0 5 5 5 4 CLASP N terminal HEAT_2 PF13646.6 GAN08379.1 - 7.7e-14 51.8 14.6 0.24 11.8 0.1 10.4 8 2 1 10 10 10 6 HEAT repeats HEAT PF02985.22 GAN08379.1 - 1e-12 47.1 13.8 0.19 12.0 0.1 11.6 11 0 0 11 11 11 4 HEAT repeat Cnd1 PF12717.7 GAN08379.1 - 1.5e-07 31.6 3.1 0.39 10.8 0.0 7.3 6 2 2 9 9 9 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAN08379.1 - 9e-07 29.3 6.2 3 8.5 0.0 7.2 6 0 0 6 6 6 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAN08379.1 - 4.9e-05 23.8 0.1 0.28 11.8 0.0 5.7 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 GAN08379.1 - 0.00063 18.4 4.9 0.062 11.8 0.0 5.2 6 1 1 7 7 7 1 Adaptin N terminal region Tti2 PF10521.9 GAN08379.1 - 0.0057 16.2 0.0 2.7 7.5 0.0 3.4 3 0 0 3 3 3 1 Tti2 family GATA PF00320.27 GAN08380.1 - 0.24 11.1 23.5 0.023 14.3 10.2 3.2 2 1 0 2 2 2 0 GATA zinc finger DZR PF12773.7 GAN08380.1 - 2.4 8.2 9.8 0.61 10.2 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF3425 PF11905.8 GAN08382.1 - 3.1e-13 49.8 0.4 3.1e-13 49.8 0.4 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAN08382.1 - 4.8e-05 23.4 8.6 4.8e-05 23.4 8.6 2.3 2 0 0 2 2 2 1 bZIP transcription factor DUF3425 PF11905.8 GAN08383.1 - 4e-09 36.5 0.4 2.5e-08 33.9 0.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 GAN08383.1 - 1.6 8.9 17.2 6.1 7.0 17.1 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Tom5 PF10642.9 GAN08383.1 - 7.2 6.7 9.5 5.5 7.1 1.5 3.6 2 1 1 3 3 3 0 Mitochondrial import receptor subunit or translocase Hydrolase_4 PF12146.8 GAN08384.1 - 3.9e-16 59.0 0.0 1.8e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN08384.1 - 4.5e-11 42.9 0.0 4.2e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN08384.1 - 7.7e-11 43.0 0.0 9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAN08384.1 - 0.00081 19.0 0.0 0.0027 17.3 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAN08384.1 - 0.017 14.6 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 GAN08384.1 - 0.09 12.5 0.0 9.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 GAN08384.1 - 0.11 12.6 0.0 2.3 8.3 0.0 2.6 2 1 0 2 2 2 0 Thioesterase domain EamA PF00892.20 GAN08385.1 - 0.00033 20.9 13.2 0.00088 19.5 13.2 1.7 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 GAN08385.1 - 0.001 19.1 0.7 0.0012 18.8 0.7 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 UAA PF08449.11 GAN08385.1 - 0.044 13.0 3.4 0.055 12.7 3.4 1.2 1 0 0 1 1 1 0 UAA transporter family Nup54 PF13874.6 GAN08386.1 - 7.8e-39 133.0 8.8 7.8e-39 133.0 8.8 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 GAN08386.1 - 1.7e-07 32.0 106.4 2.3e-07 31.5 25.8 3.6 1 1 2 3 3 3 2 Nucleoporin FG repeat region CorA PF01544.18 GAN08386.1 - 0.016 14.6 2.5 0.027 13.8 2.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Polysacc_deac_1 PF01522.21 GAN08387.1 - 4.9e-09 36.1 0.0 1.3e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase Sec7 PF01369.20 GAN08388.1 - 1.1e-64 217.5 0.4 2e-64 216.7 0.4 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAN08388.1 - 3e-19 69.5 0.0 2.4e-18 66.5 0.0 2.6 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ECM1 PF05782.11 GAN08390.1 - 0.027 13.4 0.2 0.03 13.3 0.2 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Ras PF00071.22 GAN08391.1 - 1.6e-46 157.9 0.1 2.2e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN08391.1 - 1.3e-31 109.3 0.1 2.2e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN08391.1 - 5.7e-12 45.4 0.1 7.5e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN08391.1 - 1.7e-06 27.6 0.1 2.6e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2235 PF09994.9 GAN08392.1 - 2.2e-71 240.6 0.0 2.8e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RasGEF PF00617.19 GAN08393.1 - 4.7e-51 173.5 1.0 1e-50 172.4 1.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN08393.1 - 1.3e-10 41.5 1.4 1.3e-10 41.5 1.4 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif THOC7 PF05615.13 GAN08393.1 - 0.81 10.0 8.5 0.42 10.9 2.2 2.9 2 0 0 2 2 2 0 Tho complex subunit 7 Zip PF02535.22 GAN08395.1 - 0.0036 16.6 0.3 0.0036 16.6 0.3 2.1 1 1 1 2 2 2 1 ZIP Zinc transporter WBP-1 PF11669.8 GAN08395.1 - 0.069 13.8 1.0 0.14 12.8 0.1 2.0 1 1 1 2 2 2 0 WW domain-binding protein 1 DUF4131 PF13567.6 GAN08395.1 - 3.3 7.3 4.4 8 6.1 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EF-hand_1 PF00036.32 GAN08396.1 - 4.7e-36 119.6 11.9 5.4e-09 35.0 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN08396.1 - 4.7e-31 107.1 10.5 2.8e-15 56.5 1.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAN08396.1 - 9.5e-26 88.1 12.2 3.3e-08 32.7 0.1 4.6 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAN08396.1 - 1.1e-25 87.3 11.7 5.6e-06 25.9 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAN08396.1 - 2e-17 62.8 14.4 5.4e-09 35.8 3.0 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 GAN08396.1 - 5.2e-10 39.2 2.2 2.1e-05 24.4 0.3 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAN08396.1 - 3.2e-09 37.0 0.6 6.8e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAN08396.1 - 8.3e-09 35.8 5.2 3.5e-05 24.1 0.6 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 GAN08396.1 - 3e-07 30.7 1.0 0.00021 21.5 0.2 2.4 1 1 1 2 2 2 2 p25-alpha TerB PF05099.13 GAN08396.1 - 4.2e-05 23.5 1.0 1.4 8.9 0.0 3.1 2 1 1 3 3 3 2 Tellurite resistance protein TerB EF-hand_14 PF17959.1 GAN08396.1 - 8.4e-05 22.8 1.4 0.016 15.6 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.13 GAN08396.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 GAN08396.1 - 0.026 15.4 0.2 2.3 9.2 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 GAN08396.1 - 0.054 13.4 0.8 0.054 13.4 0.8 3.4 3 1 0 3 3 3 0 EF hand DUF1456 PF07308.13 GAN08396.1 - 0.084 13.2 0.7 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Dockerin_1 PF00404.18 GAN08396.1 - 0.13 12.4 7.1 6.8 7.0 1.4 3.3 2 1 0 2 2 2 0 Dockerin type I domain Glycos_trans_3N PF02885.17 GAN08396.1 - 0.19 11.6 0.4 9.2 6.2 0.1 3.0 2 1 1 3 3 3 0 Glycosyl transferase family, helical bundle domain IF-2B PF01008.17 GAN08398.1 - 5.2e-06 25.9 0.0 5.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Mg_trans_NIPA PF05653.14 GAN08399.1 - 3.3e-83 279.2 21.4 4.3e-83 278.8 21.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAN08399.1 - 5e-06 26.7 7.3 5e-06 26.7 7.3 2.2 2 0 0 2 2 2 1 EamA-like transporter family Ycf66_N PF07444.11 GAN08399.1 - 0.067 13.3 2.4 0.71 10.0 0.4 2.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF3836 PF12930.7 GAN08399.1 - 0.11 12.2 1.3 0.66 9.7 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF3836) DUF2937 PF11157.8 GAN08399.1 - 0.17 11.6 0.8 6.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) eIF3g PF12353.8 GAN08400.1 - 0.26 11.7 1.5 0.32 11.4 1.5 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G PLDc PF00614.22 GAN08401.1 - 5.6e-17 61.1 0.9 1.4e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAN08401.1 - 5.2e-15 55.5 0.0 2.5e-07 30.7 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain DUF4090 PF13319.6 GAN08401.1 - 0.2 11.9 0.8 0.75 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) Utp12 PF04003.12 GAN08402.1 - 1.7e-24 86.2 0.0 3.1e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAN08402.1 - 1.3e-08 35.0 3.5 0.04 14.2 0.0 4.6 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN08402.1 - 2.5e-06 28.1 2.3 0.0087 16.9 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat CSTF2_hinge PF14327.6 GAN08402.1 - 0.045 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 PIN_4 PF13638.6 GAN08403.1 - 4.5e-21 75.5 0.5 1.9e-20 73.5 0.2 2.3 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 GAN08403.1 - 9.2e-09 35.2 0.6 4.3e-08 33.0 0.6 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF1657 PF07870.11 GAN08403.1 - 0.2 11.6 1.5 0.3 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) zf-C2H2 PF00096.26 GAN08404.1 - 0.078 13.5 1.0 0.69 10.5 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN08404.1 - 0.14 13.1 2.5 0.55 11.2 0.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger PDEase_I PF00233.19 GAN08405.1 - 3.6e-61 206.9 0.2 5.9e-61 206.2 0.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Terminase_3 PF04466.13 GAN08405.1 - 0.036 13.6 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 Phage terminase large subunit HD PF01966.22 GAN08405.1 - 0.08 13.2 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 HD domain Ribosomal_L19e PF01280.20 GAN08406.1 - 2.6e-53 180.0 11.6 3.3e-53 179.6 11.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e Alpha_TIF PF02232.15 GAN08406.1 - 0.012 14.8 2.4 0.015 14.4 2.4 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) CNH PF00780.22 GAN08407.1 - 9.1e-42 143.6 0.0 1.4e-41 142.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAN08407.1 - 1.8e-40 139.1 1.1 3.9e-40 138.0 1.1 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 GAN08407.1 - 4.7e-23 81.8 0.3 2.4e-22 79.5 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 GAN08407.1 - 2e-06 27.7 0.1 1.3e-05 25.2 0.2 2.4 2 1 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RRM_1 PF00076.22 GAN08408.1 - 4.3e-07 29.7 0.0 6.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIG-H PF10181.9 GAN08409.1 - 2.9e-19 68.7 0.2 4.9e-19 68.0 0.2 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Memo PF01875.17 GAN08410.1 - 1.5e-76 257.1 0.1 2.2e-76 256.6 0.1 1.2 1 0 0 1 1 1 1 Memo-like protein WD40 PF00400.32 GAN08410.1 - 3.1e-33 113.3 10.1 3.3e-06 27.7 0.1 8.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08410.1 - 9.3e-09 35.5 1.5 0.1 12.9 0.2 5.6 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN08410.1 - 0.0002 20.2 11.0 0.36 9.4 0.1 5.0 3 1 1 5 5 5 2 Nucleoporin Nup120/160 MMS1_N PF10433.9 GAN08410.1 - 0.0029 16.3 1.3 0.012 14.3 1.1 2.2 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PALB2_WD40 PF16756.5 GAN08410.1 - 0.0059 15.6 0.1 0.048 12.6 0.1 2.3 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain DDHD PF02862.17 GAN08410.1 - 0.0079 16.4 1.3 0.013 15.6 1.3 1.4 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 GAN08410.1 - 0.018 15.1 20.4 0.026 14.5 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSG2 PF16965.5 GAN08410.1 - 0.056 12.4 8.2 0.086 11.8 8.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4175 PF13779.6 GAN08410.1 - 0.14 10.0 25.0 0.21 9.4 25.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S15 PF02129.18 GAN08410.1 - 0.25 10.9 8.2 0.45 10.1 8.2 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pex14_N PF04695.13 GAN08410.1 - 0.29 11.8 17.2 0.52 10.9 17.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hira PF07569.11 GAN08410.1 - 0.48 10.1 0.0 0.48 10.1 0.0 4.1 3 1 1 4 4 3 0 TUP1-like enhancer of split TMEM51 PF15345.6 GAN08410.1 - 0.55 10.0 10.3 0.28 11.0 7.3 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 Presenilin PF01080.17 GAN08410.1 - 1.1 8.0 9.7 1.6 7.4 9.7 1.2 1 0 0 1 1 1 0 Presenilin XRCC4 PF06632.12 GAN08410.1 - 1.1 8.1 11.8 2 7.2 11.8 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 YfhO PF09586.10 GAN08410.1 - 1.9 6.6 6.4 2.6 6.2 6.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO eIF-3_zeta PF05091.12 GAN08410.1 - 2.2 7.2 15.6 3.4 6.6 15.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 GAN08410.1 - 5.4 6.3 7.3 8.8 5.6 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 GAN08410.1 - 7.8 5.2 9.9 12 4.6 9.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.25 GAN08411.1 - 1.2e-64 218.3 0.1 1.5e-64 218.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08411.1 - 9.3e-42 143.1 0.0 1.6e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN08411.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN08411.1 - 0.0029 17.0 1.5 0.01 15.2 1.5 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAN08411.1 - 0.0031 16.9 0.0 0.022 14.1 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAN08411.1 - 0.019 13.9 0.7 0.036 13.0 0.7 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 GAN08411.1 - 0.06 12.9 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 GAN08411.1 - 0.14 11.7 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_L35Ae PF01247.18 GAN08412.1 - 1.6e-42 143.6 0.9 1.8e-42 143.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAN08412.1 - 0.0014 18.8 0.1 0.28 11.5 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Bcr-Abl_Oligo PF09036.10 GAN08412.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Glyoxalase PF00903.25 GAN08413.1 - 4.6e-21 75.4 0.9 8.9e-16 58.2 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAN08413.1 - 1.1e-11 45.0 0.1 1.8e-05 25.0 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GAN08413.1 - 4.5e-07 30.1 0.1 1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GAN08413.1 - 2.2e-06 27.9 0.4 0.00058 20.0 0.1 3.0 3 1 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 GAN08413.1 - 0.06 14.2 0.9 1 10.2 0.1 2.7 2 2 0 2 2 2 0 Glyoxalase-like domain Med18 PF09637.10 GAN08414.1 - 1.4e-23 84.1 0.1 9.3e-22 78.1 0.1 2.0 1 1 0 1 1 1 1 Med18 protein UPF0020 PF01170.18 GAN08415.1 - 4e-23 82.1 0.0 9.1e-11 41.8 0.1 2.2 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 GAN08415.1 - 1.1e-07 31.5 0.0 3.5e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAN08415.1 - 3.9e-05 24.3 0.1 0.00049 20.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN08415.1 - 0.00028 21.5 0.0 0.00068 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN08415.1 - 0.00034 20.2 0.0 0.0089 15.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAN08415.1 - 0.0048 16.4 0.1 0.02 14.4 0.1 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 GAN08415.1 - 0.0075 16.1 0.1 0.12 12.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08415.1 - 0.0093 15.8 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain N6_N4_Mtase PF01555.18 GAN08415.1 - 0.023 14.4 0.4 0.95 9.1 0.1 2.6 3 0 0 3 3 3 0 DNA methylase N6_Mtase PF02384.16 GAN08415.1 - 0.04 13.2 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 N-6 DNA Methylase Vps26 PF03643.15 GAN08416.1 - 2.3e-84 282.7 3.4 2.1e-59 200.8 1.8 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAN08416.1 - 0.015 15.3 0.5 0.31 11.1 0.5 2.5 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain UMP1 PF05348.11 GAN08416.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Pkinase PF00069.25 GAN08417.1 - 1.5e-56 191.7 0.0 2.1e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08417.1 - 2.4e-33 115.5 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN08417.1 - 1.2e-06 28.1 0.0 4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAN08417.1 - 0.00032 20.4 0.1 0.36 10.4 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GAN08417.1 - 0.003 16.4 1.1 0.017 14.0 1.1 2.2 1 1 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 GAN08419.1 - 3.3e-15 55.7 0.0 5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GAN08419.1 - 7.1e-10 39.3 9.0 7.1e-10 39.3 9.0 2.7 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_8 PF11835.8 GAN08419.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 1 RRM-like domain SH3_9 PF14604.6 GAN08420.1 - 7.3e-12 45.0 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN08420.1 - 8.9e-11 41.2 0.1 1.8e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN08420.1 - 1.6e-08 34.1 0.0 2.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3807 PF12720.7 GAN08420.1 - 0.98 9.7 25.2 1.4 9.2 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Brix PF04427.18 GAN08421.1 - 6.7e-27 94.9 0.1 1.2e-26 94.1 0.1 1.4 1 0 0 1 1 1 1 Brix domain TBPIP_N PF15517.6 GAN08421.1 - 0.065 13.3 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 TBP-interacting protein N-terminus RIO1 PF01163.22 GAN08421.1 - 0.08 12.5 0.0 0.08 12.5 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Rrn6 PF10214.9 GAN08421.1 - 1.1 7.7 4.8 1.4 7.3 4.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pox_Ag35 PF03286.14 GAN08421.1 - 2 8.1 12.3 3.1 7.5 12.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PIN_8 PF18476.1 GAN08421.1 - 6.8 6.5 11.3 3.4 7.4 5.4 2.2 2 0 0 2 2 2 0 PIN like domain Myb_DNA-binding PF00249.31 GAN08422.1 - 1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain U-box PF04564.15 GAN08422.1 - 0.0029 17.7 0.2 0.064 13.4 0.0 2.8 2 1 1 3 3 3 1 U-box domain DUF3510 PF12022.8 GAN08422.1 - 0.0062 16.9 0.5 0.0062 16.9 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) DUF1296 PF06972.11 GAN08422.1 - 0.016 15.3 0.1 0.046 13.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) IMUP PF15761.5 GAN08422.1 - 6.4 7.5 7.4 0.25 12.1 1.3 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Myb_DNA-bind_7 PF15963.5 GAN08422.1 - 7.8 6.5 9.0 1.7 8.6 0.0 3.7 3 2 1 5 5 5 0 Myb DNA-binding like Thioredox_DsbH PF03190.15 GAN08424.1 - 3.6e-57 192.9 0.1 7.3e-57 191.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 GAN08424.1 - 9.2e-10 38.6 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 GAN08424.1 - 9.8e-06 24.9 0.3 0.0001 21.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 GAN08424.1 - 2.8e-05 22.8 0.5 9.3e-05 21.1 0.0 1.9 2 1 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 GAN08424.1 - 0.015 14.8 1.7 3.6 7.0 0.1 3.3 3 1 1 4 4 4 0 D-glucuronyl C5-epimerase C-terminus Thioredoxin_2 PF13098.6 GAN08424.1 - 0.022 15.2 0.0 0.059 13.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain GlcNAc_2-epim PF07221.11 GAN08424.1 - 0.03 13.6 0.1 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Ribosomal_L7Ae PF01248.26 GAN08425.1 - 4.6e-26 90.4 0.0 5.3e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EF_TS PF00889.19 GAN08426.1 - 3e-32 111.9 0.1 9e-25 87.5 0.0 2.5 1 1 1 2 2 2 2 Elongation factor TS DUF5309 PF17236.2 GAN08426.1 - 0.005 16.2 0.4 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5309) HBS1_N PF08938.10 GAN08426.1 - 0.036 14.4 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 HBS1 N-terminus Ribosomal_L23eN PF03939.13 GAN08427.1 - 8.2e-23 80.4 8.0 1.7e-22 79.4 8.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GAN08427.1 - 4.7e-15 55.7 2.3 4.7e-15 55.7 2.3 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 PTPRCAP PF15713.5 GAN08428.1 - 0.0015 18.8 1.0 0.0015 18.8 1.0 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Prothymosin PF03247.14 GAN08428.1 - 0.02 15.4 11.9 0.03 14.8 11.9 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family TP53IP5 PF15331.6 GAN08428.1 - 0.039 14.1 0.9 0.041 14.0 0.9 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Asp PF00026.23 GAN08429.1 - 6.6e-71 239.3 0.1 8.1e-71 239.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN08429.1 - 1.9e-13 51.1 2.8 1.3e-09 38.5 0.2 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN08429.1 - 0.00095 19.0 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp PF00026.23 GAN08430.1 - 4.4e-74 249.7 0.7 5.2e-73 246.2 0.7 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN08430.1 - 7.5e-14 52.4 2.3 2.3e-08 34.5 0.1 4.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN08430.1 - 0.0024 17.6 0.2 0.018 14.8 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal LIP1 PF15904.5 GAN08430.1 - 0.015 15.7 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Asp_protease_2 PF13650.6 GAN08430.1 - 0.087 13.5 0.4 7.8 7.2 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.23 GAN08431.1 - 4.9e-67 226.6 2.4 1.2e-66 225.3 2.4 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN08431.1 - 6.3e-14 52.6 10.8 1.3e-08 35.2 0.1 3.8 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAN08431.1 - 0.0006 19.6 0.0 0.0017 18.1 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAN08431.1 - 0.0031 18.1 2.9 0.018 15.6 0.2 2.9 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 GAN08431.1 - 0.041 14.4 0.7 0.63 10.6 0.3 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Big_1 PF02369.16 GAN08431.1 - 0.36 10.9 10.0 0.25 11.4 5.2 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) ArAE_2 PF10334.9 GAN08432.1 - 4.9e-21 75.6 0.1 8.4e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 GAN08432.1 - 7.3e-16 58.4 14.9 7.3e-16 58.4 14.9 3.1 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 GAN08432.1 - 2.8e-13 49.7 8.6 6.2e-13 48.6 2.2 2.8 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 GAN08432.1 - 3.6e-06 25.8 6.4 3.6e-06 25.8 6.4 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF3149 PF11346.8 GAN08432.1 - 0.013 15.1 1.8 2 8.1 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) ALMT PF11744.8 GAN08432.1 - 0.12 11.2 13.5 0.012 14.4 7.2 2.3 2 1 0 2 2 2 0 Aluminium activated malate transporter TPT PF03151.16 GAN08433.1 - 0.00014 21.4 14.8 0.00023 20.6 14.8 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN08433.1 - 0.00032 20.9 9.0 0.00032 20.9 9.0 2.1 2 0 0 2 2 2 1 EamA-like transporter family PHO4 PF01384.20 GAN08433.1 - 6.6 5.7 19.3 0.092 11.8 6.3 2.3 1 1 0 2 2 2 0 Phosphate transporter family Questin_oxidase PF14027.6 GAN08434.1 - 2e-93 313.7 0.2 3.2e-93 313.0 0.2 1.3 1 0 0 1 1 1 1 Questin oxidase-like DUF1910 PF08928.10 GAN08434.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) HECW1_helix PF18436.1 GAN08434.1 - 0.13 12.4 1.2 0.99 9.6 0.0 3.1 4 0 0 4 4 4 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 BCDHK_Adom3 PF10436.9 GAN08435.1 - 5.8e-42 143.3 0.0 9.2e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAN08435.1 - 5.8e-14 52.6 0.0 1.4e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAN08435.1 - 0.0082 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAN08435.1 - 0.027 14.4 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 GAN08435.1 - 0.095 12.6 0.0 0.3 11.0 0.0 1.8 1 1 0 1 1 1 0 GHKL domain IATP PF04568.12 GAN08436.1 - 8e-05 23.0 1.0 0.0001 22.6 1.0 1.4 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP MIP-T3_C PF17749.1 GAN08436.1 - 0.014 15.4 0.4 0.02 14.9 0.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region CHCH PF06747.13 GAN08437.1 - 5.5e-05 23.2 6.3 8.2e-05 22.6 6.3 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 GAN08437.1 - 0.0016 18.5 21.7 0.0016 18.5 21.7 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) MTCP1 PF08991.10 GAN08437.1 - 0.032 14.4 3.2 0.053 13.8 3.2 1.3 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 GAN08437.1 - 0.12 12.4 2.1 0.21 11.6 2.1 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-BED PF02892.15 GAN08438.1 - 1e-05 25.5 0.3 2.3e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 BED zinc finger YjbH PF06082.11 GAN08438.1 - 0.13 11.0 2.6 0.067 12.0 0.7 1.4 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH p450 PF00067.22 GAN08439.1 - 1.7e-54 185.3 0.0 2.2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_6 PF13516.6 GAN08442.1 - 4.3e-06 26.4 20.3 0.034 14.2 0.2 8.7 10 0 0 10 10 10 2 Leucine Rich repeat LRR_4 PF12799.7 GAN08442.1 - 0.00069 20.0 19.7 0.78 10.3 0.1 6.7 5 3 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN08442.1 - 0.21 12.2 21.3 28 5.8 0.1 8.9 8 1 2 10 10 10 0 Leucine Rich Repeat CsbD PF05532.12 GAN08443.1 - 5.1e-05 23.1 3.6 8.8e-05 22.3 3.6 1.3 1 0 0 1 1 1 1 CsbD-like Forkhead PF00250.18 GAN08444.1 - 6.2e-32 109.7 0.1 1.2e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain Vta1 PF04652.16 GAN08445.1 - 3.2e-49 166.6 3.4 1.3e-48 164.6 1.4 2.1 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 GAN08445.1 - 2.6e-14 52.6 1.7 2.6e-14 52.6 1.7 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain Peripla_BP_6 PF13458.6 GAN08445.1 - 0.034 13.8 0.5 0.057 13.1 0.1 1.7 2 0 0 2 2 2 0 Periplasmic binding protein PCI PF01399.27 GAN08446.1 - 5e-23 81.6 1.4 5e-23 81.6 1.4 3.1 4 1 0 4 4 4 1 PCI domain GCP_N_terminal PF17681.1 GAN08446.1 - 0.00055 19.7 1.6 0.098 12.3 0.9 2.2 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal ACDC PF14733.6 GAN08446.1 - 0.93 9.8 4.1 1.7 9.0 0.5 2.9 2 1 1 3 3 3 0 AP2-coincident C-terminal COG7 PF10191.9 GAN08447.1 - 3.1e-16 58.8 7.2 3.1e-16 58.8 7.2 1.5 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) Pex14_N PF04695.13 GAN08447.1 - 0.0017 19.0 5.0 0.0035 18.0 5.0 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4746 PF15928.5 GAN08447.1 - 0.013 15.0 11.9 0.016 14.6 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Membralin PF09746.9 GAN08447.1 - 0.13 11.2 5.0 0.19 10.8 5.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 GAN08447.1 - 0.4 9.4 11.9 0.52 9.1 11.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 GAN08447.1 - 0.49 8.3 7.7 0.55 8.1 7.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dsh_C PF12316.8 GAN08447.1 - 0.59 10.5 6.9 0.76 10.1 6.3 1.4 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Asp-B-Hydro_N PF05279.11 GAN08447.1 - 0.64 10.0 17.7 0.73 9.8 17.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Plasmodium_Vir PF05795.11 GAN08447.1 - 1.6 8.1 6.3 2.7 7.3 6.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF3_subunit PF08597.10 GAN08447.1 - 1.6 8.6 25.8 0.71 9.7 23.1 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 GAN08447.1 - 2.8 6.1 16.1 3.6 5.8 16.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 GAN08447.1 - 4.5 7.3 13.7 2.7 8.0 12.1 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Med19 PF10278.9 GAN08447.1 - 5.7 6.8 17.7 12 5.7 17.7 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RGS_DHEX PF18148.1 GAN08447.1 - 7 6.8 13.5 4.9 7.3 11.6 1.7 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain TPR_1 PF00515.28 GAN08448.1 - 1.3e-06 28.0 3.5 0.003 17.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAN08448.1 - 3e-06 26.9 1.6 1 9.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN08448.1 - 0.002 18.2 5.0 0.012 15.8 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaJ PF00226.31 GAN08448.1 - 0.0058 16.7 0.0 0.026 14.6 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.31 GAN08448.1 - 0.01 15.7 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain TPR_12 PF13424.6 GAN08448.1 - 0.035 14.4 4.2 0.37 11.1 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat FAM176 PF14851.6 GAN08448.1 - 4.7 6.9 8.1 1.9 8.1 1.3 2.4 2 0 0 2 2 2 0 FAM176 family GATase_4 PF13230.6 GAN08450.1 - 1e-18 67.2 0.1 1.1e-17 63.9 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAN08450.1 - 3e-09 37.2 0.0 5.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Rho_N PF07498.12 GAN08450.1 - 0.093 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Anp1 PF03452.14 GAN08451.1 - 1e-92 310.3 0.3 1.2e-92 310.0 0.3 1.1 1 0 0 1 1 1 1 Anp1 NAD_Gly3P_dh_N PF01210.23 GAN08453.1 - 1.1e-52 178.2 0.2 1.9e-52 177.4 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 GAN08453.1 - 1.5e-47 161.4 0.2 3.6e-47 160.2 0.2 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 GAN08453.1 - 0.0011 19.5 1.1 0.15 12.6 1.1 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sigma70_r1_1 PF03979.14 GAN08453.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 RRM_1 PF00076.22 GAN08454.1 - 1.3e-15 56.9 0.1 2.2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.11 GAN08454.1 - 0.00094 18.4 5.5 0.00094 18.4 5.5 2.5 2 1 1 3 3 3 2 Plant specific eukaryotic initiation factor 4B HSF_DNA-bind PF00447.17 GAN08455.1 - 8.4e-33 112.9 2.3 8.4e-33 112.9 2.3 2.2 2 1 0 2 2 2 1 HSF-type DNA-binding Cor1 PF04803.12 GAN08455.1 - 0.012 15.9 7.8 0.022 14.9 7.8 1.5 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region TRF PF08558.10 GAN08455.1 - 0.013 15.1 2.1 0.023 14.3 2.1 1.3 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) TraB PF01963.17 GAN08455.1 - 0.025 14.5 0.7 0.036 13.9 0.7 1.2 1 0 0 1 1 1 0 TraB family Cep57_CLD_2 PF14197.6 GAN08455.1 - 0.029 14.5 3.0 0.07 13.2 3.0 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 AAA_24 PF13479.6 GAN08455.1 - 0.036 13.8 0.5 0.059 13.1 0.5 1.3 1 0 0 1 1 1 0 AAA domain CortBP2 PF09727.9 GAN08455.1 - 0.11 12.5 6.7 0.17 11.8 6.7 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 DHR10 PF18595.1 GAN08455.1 - 0.14 12.2 5.7 0.23 11.5 5.7 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain AIG1 PF04548.16 GAN08455.1 - 0.52 9.6 5.4 0.81 9.0 5.4 1.3 1 0 0 1 1 1 0 AIG1 family Snapin_Pallidin PF14712.6 GAN08455.1 - 2.5 8.6 9.7 3.8 8.0 8.2 2.0 1 1 1 2 2 2 0 Snapin/Pallidin SseC PF04888.12 GAN08455.1 - 6.8 6.2 10.5 13 5.2 10.5 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family COPI_assoc PF08507.10 GAN08456.1 - 5.7e-16 58.8 6.2 7.3e-16 58.4 6.2 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2207 PF09972.9 GAN08456.1 - 3.3 6.4 6.2 14 4.3 6.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PEX11 PF05648.14 GAN08457.1 - 1.9e-19 70.0 0.2 2.8e-19 69.5 0.2 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MARVEL PF01284.23 GAN08458.1 - 2.5e-14 53.5 14.7 4.7e-14 52.6 14.7 1.4 1 0 0 1 1 1 1 Membrane-associating domain Polysacc_synt PF01943.17 GAN08458.1 - 0.0016 17.9 5.0 0.0029 17.0 5.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saf_2TM PF18303.1 GAN08458.1 - 0.48 10.0 1.4 1.4 8.5 1.4 1.8 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain DUF3084 PF11283.8 GAN08458.1 - 3.5 7.7 5.1 0.51 10.4 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) Fasciclin PF02469.22 GAN08459.1 - 3.6e-28 98.3 15.6 3.2e-22 79.1 2.4 3.9 3 1 0 3 3 3 3 Fasciclin domain eIF-3_zeta PF05091.12 GAN08459.1 - 0.65 8.9 7.2 1.4 7.8 7.3 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1631 PF07793.11 GAN08459.1 - 4.4 5.6 16.7 0.59 8.5 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Oxidored_FMN PF00724.20 GAN08460.1 - 1.2e-69 235.2 0.0 1.4e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pox_I5 PF04713.12 GAN08461.1 - 1.7 8.7 8.8 0.078 13.0 3.0 1.7 2 0 0 2 2 2 0 Poxvirus protein I5 ER_lumen_recept PF00810.18 GAN08462.1 - 2.7e-53 180.7 14.0 2.7e-53 180.7 14.0 3.0 3 0 0 3 3 3 1 ER lumen protein retaining receptor Peptidase_M50 PF02163.22 GAN08462.1 - 3e-12 46.4 0.0 5e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M50 PQ-loop PF04193.14 GAN08462.1 - 4.2 7.2 19.6 1.1 9.0 0.1 5.0 5 0 0 5 5 5 0 PQ loop repeat Ras PF00071.22 GAN08463.1 - 2.3e-63 212.6 0.8 2.8e-63 212.3 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN08463.1 - 3.1e-36 124.2 0.1 3.1e-36 124.2 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN08463.1 - 2.7e-18 66.0 0.1 3.3e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN08463.1 - 5.5e-07 29.3 0.4 1.3e-06 28.1 0.2 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN08463.1 - 6.2e-06 25.7 0.4 7.8e-06 25.4 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN08463.1 - 2.4e-05 24.4 0.1 6.3e-05 23.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAN08463.1 - 0.00013 21.4 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAN08463.1 - 0.00097 19.1 0.5 0.14 12.1 0.0 2.5 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAN08463.1 - 0.0067 16.8 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 GAN08463.1 - 0.01 15.1 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 GAN08463.1 - 0.026 14.1 0.1 1.6 8.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAN08463.1 - 0.044 14.1 0.0 0.07 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAN08463.1 - 0.044 13.5 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAN08463.1 - 0.048 14.1 0.1 0.28 11.6 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAN08463.1 - 0.071 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAN08463.1 - 0.079 13.5 0.2 0.16 12.5 0.2 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 GAN08463.1 - 0.083 12.9 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 GAN08463.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein PhyH PF05721.13 GAN08463.1 - 0.16 12.2 0.1 0.21 11.8 0.1 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) HAD_SAK_2 PF18143.1 GAN08464.1 - 0.015 15.6 0.1 0.03 14.6 0.1 1.5 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Ndc1_Nup PF09531.10 GAN08465.1 - 0.56 8.8 5.6 0.8 8.3 5.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2458 PF10454.9 GAN08467.1 - 4.8e-07 29.6 7.8 4.8e-07 29.6 7.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 GAN08467.1 - 8.1e-06 25.6 11.9 6.3e-05 22.7 11.9 2.1 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein EutB PF06751.11 GAN08467.1 - 0.058 12.2 0.2 0.075 11.9 0.2 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) DUF5526 PF17664.1 GAN08467.1 - 0.68 9.5 10.5 1.1 8.8 10.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5526) XkdW PF09636.10 GAN08467.1 - 0.96 9.6 4.8 0.97 9.6 1.2 2.5 1 1 0 2 2 2 0 XkdW protein CemA PF03040.14 GAN08467.1 - 2.2 8.2 5.9 2.3 8.1 5.1 1.3 1 1 0 1 1 1 0 CemA family Cellulase PF00150.18 GAN08468.1 - 1.8e-12 47.3 0.0 3.7e-09 36.4 0.0 3.3 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 GAN08468.1 - 1.2e-09 38.6 0.2 3.9e-09 36.9 0.2 1.9 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Exo70 PF03081.15 GAN08469.1 - 3.1e-79 266.8 2.5 3.1e-79 266.8 2.5 2.2 2 0 0 2 2 2 1 Exo70 exocyst complex subunit CNOT1_TTP_bind PF16417.5 GAN08469.1 - 0.011 14.9 0.2 0.085 12.0 0.1 2.4 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain ubiquitin PF00240.23 GAN08470.1 - 2.6e-10 39.9 0.2 5.1e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family BAG PF02179.16 GAN08470.1 - 8e-05 23.0 0.6 8e-05 23.0 0.6 1.8 2 0 0 2 2 2 1 BAG domain DUF2407 PF10302.9 GAN08470.1 - 8.9e-05 23.0 0.3 0.0003 21.3 0.3 2.0 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Hormone_1 PF00103.20 GAN08470.1 - 0.013 15.3 0.4 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Ubiquitin_5 PF18037.1 GAN08470.1 - 0.042 14.2 0.1 0.09 13.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain BP28CT PF08146.12 GAN08471.1 - 1.1e-42 145.6 1.9 1.1e-42 145.6 1.9 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 GAN08471.1 - 5.5e-22 78.3 1.4 5.5e-22 78.3 1.4 7.0 6 1 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 CNOT11 PF10155.9 GAN08471.1 - 0.026 14.7 0.9 1.1 9.4 0.0 4.4 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 HEAT PF02985.22 GAN08471.1 - 0.045 14.0 3.6 16 6.1 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat FliL PF03748.14 GAN08471.1 - 0.079 13.6 0.7 4.5 7.9 0.0 3.7 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL AMP-binding PF00501.28 GAN08472.1 - 1.3e-97 327.1 0.1 1.7e-97 326.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN08472.1 - 7.6e-24 84.5 0.0 2e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAN08472.1 - 1.1e-15 57.3 2.9 6.2e-15 54.9 0.4 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 GAN08473.1 - 3.3e-59 195.4 12.7 8.4e-09 35.9 0.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 GAN08473.1 - 5.3e-27 93.9 13.1 7.8e-27 93.4 13.1 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 GAN08473.1 - 1.1e-18 67.2 0.1 0.0011 19.2 0.0 6.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN08473.1 - 1.4e-08 34.5 0.0 0.024 14.0 0.0 4.2 3 1 1 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 GAN08473.1 - 1e-06 28.0 0.2 0.78 8.6 0.0 4.8 1 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAN08473.1 - 2.3e-06 26.6 1.0 0.19 10.3 0.1 4.4 1 1 4 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 GAN08473.1 - 0.00014 21.7 0.1 0.95 9.5 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 GAN08473.1 - 0.0029 17.0 0.0 1.6 8.0 0.0 2.9 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 GAN08473.1 - 0.016 13.8 1.2 2.1 6.8 0.3 2.6 1 1 1 2 2 2 0 Cytochrome D1 heme domain Peptidase_S9_N PF02897.15 GAN08473.1 - 0.035 12.9 0.0 2.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain CREPT PF16566.5 GAN08473.1 - 0.087 13.0 4.7 0.14 12.3 4.7 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour MMS1_N PF10433.9 GAN08473.1 - 0.093 11.3 0.0 2.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Exonuc_VII_L PF02601.15 GAN08473.1 - 0.14 11.7 1.7 0.21 11.1 1.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 GAN08473.1 - 0.2 11.5 4.2 0.3 10.9 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 GAN08473.1 - 0.56 9.6 9.1 0.81 9.1 9.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 GAN08473.1 - 0.62 10.6 9.7 1.1 9.8 9.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TPX2 PF06886.11 GAN08473.1 - 2.8 8.2 8.0 4.8 7.5 8.0 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Phage_Mu_Gam PF07352.12 GAN08473.1 - 5.6 6.9 8.9 4.5 7.2 4.3 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein FAD_binding_1 PF00667.20 GAN08474.1 - 1.1e-43 149.3 0.0 1.8e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN08474.1 - 1.6e-32 112.6 0.0 4.3e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GAN08474.1 - 3.3e-15 56.7 0.0 8.6e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glyco_trans_A_1 PF09318.10 GAN08474.1 - 0.025 14.3 0.3 0.047 13.4 0.3 1.4 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A Flavodoxin_3 PF12641.7 GAN08474.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Ank_2 PF12796.7 GAN08475.1 - 0.00018 22.0 0.3 0.0022 18.6 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAN08475.1 - 0.00046 20.5 0.5 0.0023 18.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAN08475.1 - 0.00067 20.2 0.0 0.0029 18.2 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN08475.1 - 0.0045 17.4 0.1 0.03 14.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat DUF5540 PF17694.1 GAN08476.1 - 0.027 15.0 0.4 0.64 10.6 0.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5540) PDZ_5 PF17817.1 GAN08476.1 - 0.077 13.3 2.6 0.084 13.2 0.2 2.3 2 0 0 2 2 2 0 PDZ domain GAF_2 PF13185.6 GAN08477.1 - 1.2e-11 45.1 0.0 1.7e-11 44.5 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 GAN08477.1 - 1.2e-08 35.7 0.0 1.6e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 GAN08477.1 - 0.0013 19.1 0.0 0.002 18.5 0.0 1.3 1 1 0 1 1 1 1 GAF domain SH3_9 PF14604.6 GAN08478.1 - 8.5e-08 31.9 0.2 2.7e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAN08478.1 - 2.1e-07 30.5 0.0 0.00012 21.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAN08478.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CYYR1 PF10873.8 GAN08478.1 - 0.012 16.0 1.6 0.027 14.9 1.6 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 HNH_5 PF14279.6 GAN08478.1 - 0.021 14.7 2.3 0.45 10.4 0.1 2.6 2 0 0 2 2 2 0 HNH endonuclease Glycophorin_A PF01102.18 GAN08478.1 - 0.057 13.7 0.1 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 Glycophorin A Syndecan PF01034.20 GAN08478.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Ribosomal_S21e PF01249.18 GAN08479.1 - 4.4e-39 132.4 0.1 5.3e-39 132.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Homeodomain PF00046.29 GAN08480.1 - 4.4e-17 61.7 1.9 1.2e-16 60.3 1.9 1.8 1 0 0 1 1 1 1 Homeodomain RCR PF12273.8 GAN08481.1 - 0.01 16.5 1.0 0.025 15.2 0.0 2.2 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red ATP_synt_H PF05493.13 GAN08481.1 - 0.15 12.5 0.0 0.15 12.5 0.0 4.0 3 1 1 4 4 4 0 ATP synthase subunit H CBP4 PF07960.11 GAN08482.1 - 3.3e-15 56.1 0.0 3.6e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 GAN08482.1 - 0.00011 22.1 0.4 0.00013 21.8 0.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF1682 PF07946.14 GAN08483.1 - 1e-81 274.7 2.1 1.2e-81 274.4 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) U79_P34 PF03064.16 GAN08483.1 - 0.029 13.7 3.3 0.044 13.1 3.3 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNaseH_C PF09293.10 GAN08483.1 - 0.11 12.9 1.1 2.6 8.4 0.0 3.0 3 0 0 3 3 3 0 T4 RNase H, C terminal DUF3619 PF12279.8 GAN08483.1 - 0.21 11.9 5.6 0.45 10.9 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) SRI PF08236.11 GAN08483.1 - 1.2 9.3 10.9 0.35 11.1 7.3 1.9 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain CYSTM PF12734.7 GAN08485.1 - 0.0068 16.7 25.3 0.019 15.2 25.3 1.9 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance Myotub-related PF06602.14 GAN08486.1 - 2.4e-150 500.4 0.3 2.9e-150 500.1 0.3 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 GAN08486.1 - 0.0043 16.7 0.2 0.011 15.3 0.1 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAN08486.1 - 0.034 14.0 0.1 0.076 12.8 0.1 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain GluRS_N PF18466.1 GAN08486.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain Mannosyl_trans PF05007.13 GAN08488.1 - 2.3e-80 270.2 34.0 3.4e-80 269.6 27.1 2.7 2 2 0 2 2 2 1 Mannosyltransferase (PIG-M) MPC PF03650.13 GAN08489.1 - 5.9e-35 119.7 0.0 6.5e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Sedlin_N PF04628.13 GAN08490.1 - 1.2e-29 103.1 0.4 1.4e-29 102.9 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAN08490.1 - 0.0022 17.9 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family CNOT1_CAF1_bind PF16415.5 GAN08490.1 - 0.093 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Metallophos PF00149.28 GAN08491.1 - 1e-18 68.6 0.0 4e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Nudix_N_2 PF14803.6 GAN08491.1 - 0.054 13.4 0.1 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 Nudix N-terminal HCV_NS5a PF01506.19 GAN08491.1 - 0.92 9.4 3.7 1.8 8.5 3.7 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor Ras PF00071.22 GAN08492.1 - 2.2e-61 206.2 0.2 6.7e-61 204.6 0.1 1.8 2 0 0 2 2 2 1 Ras family FA_desaturase PF00487.24 GAN08492.1 - 4.8e-43 147.8 10.5 6.9e-43 147.3 10.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Roc PF08477.13 GAN08492.1 - 9.6e-35 119.4 0.1 2.3e-34 118.2 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Cyt-b5 PF00173.28 GAN08492.1 - 7e-15 54.9 0.2 3.4e-14 52.8 0.0 2.4 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.21 GAN08492.1 - 4e-12 45.9 0.1 6.7e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN08492.1 - 2.1e-06 27.8 0.4 3.9e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN08492.1 - 0.0036 17.2 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAN08492.1 - 0.014 14.9 0.1 0.048 13.2 0.1 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAN08492.1 - 0.015 15.5 0.1 0.097 12.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 GAN08492.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAN08492.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAN08492.1 - 0.053 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 GAN08492.1 - 0.09 12.2 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 GAN08492.1 - 0.091 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GAN08492.1 - 0.1 13.0 0.2 0.23 11.8 0.1 1.7 2 1 0 2 2 1 0 AAA ATPase domain DLIC PF05783.11 GAN08492.1 - 0.1 11.4 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2207 PF09972.9 GAN08492.1 - 0.71 8.6 4.8 8.4 5.0 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Rib PF08428.10 GAN08496.1 - 0.029 14.3 0.1 0.097 12.7 0.1 1.9 2 0 0 2 2 2 0 Rib/alpha-like repeat Zmiz1_N PF18028.1 GAN08497.1 - 0.23 11.8 1.9 4.3 7.7 0.0 3.6 3 0 0 3 3 3 0 Zmiz1 N-terminal tetratricopeptide repeat domain Goodbye PF17109.5 GAN08497.1 - 1.3 9.5 4.9 0.97 9.9 0.1 3.3 4 1 0 4 4 4 0 fungal STAND N-terminal Goodbye domain BLOC1_2 PF10046.9 GAN08497.1 - 6.9 7.1 13.1 2.9 8.2 0.0 4.9 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BCHF PF07284.11 GAN08498.1 - 0.014 15.4 0.2 0.018 15.0 0.2 1.2 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Myb_DNA-binding PF00249.31 GAN08499.1 - 1.2e-53 179.1 21.6 1.5e-14 53.9 0.4 6.2 5 1 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN08499.1 - 1.5e-42 143.6 15.2 1.6e-16 60.3 0.7 6.4 3 2 3 6 6 6 5 Myb-like DNA-binding domain BUD22 PF09073.10 GAN08499.1 - 2.1e-17 63.6 87.9 6.3e-12 45.6 48.8 4.5 3 1 1 4 4 4 2 BUD22 SANT_DAMP1_like PF16282.5 GAN08499.1 - 0.0013 18.9 5.9 10 6.4 0.3 4.4 2 1 2 4 4 4 3 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 GAN08499.1 - 0.033 14.2 0.0 0.033 14.2 0.0 6.7 5 1 3 8 8 8 0 SLIDE Myb_DNA-bind_7 PF15963.5 GAN08499.1 - 0.063 13.2 0.1 0.063 13.2 0.1 7.2 4 1 2 6 6 6 0 Myb DNA-binding like Rap1_C PF11626.8 GAN08499.1 - 2 8.5 7.0 17 5.6 0.1 3.5 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HIG_1_N PF04588.13 GAN08500.1 - 8.5e-08 32.3 0.9 8.5e-08 32.3 0.9 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 GAN08500.1 - 0.016 15.1 0.1 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein FAD_oxidored PF12831.7 GAN08500.1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Romo1 PF10247.9 GAN08500.1 - 0.24 11.8 3.8 0.15 12.4 0.8 2.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Prp19 PF08606.11 GAN08501.1 - 1.9e-33 114.2 2.5 3.5e-33 113.4 2.5 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 GAN08501.1 - 6.4e-26 90.1 9.0 0.00016 22.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08501.1 - 1.7e-16 60.2 0.1 0.00035 20.8 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 GAN08501.1 - 0.0013 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 GAN08501.1 - 0.0019 17.3 0.0 0.077 11.9 0.0 2.4 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3450 PF11932.8 GAN08501.1 - 0.0027 17.0 0.5 0.0053 16.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF1631 PF07793.11 GAN08501.1 - 0.0088 14.5 2.5 0.012 14.1 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Nup160 PF11715.8 GAN08501.1 - 0.033 12.8 0.7 1.4 7.4 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ribosomal_S17 PF00366.20 GAN08501.1 - 0.062 13.4 0.0 7.1 6.8 0.0 3.5 3 0 0 3 3 3 0 Ribosomal protein S17 zf-Nse PF11789.8 GAN08501.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit VWA_2 PF13519.6 GAN08502.1 - 5.3e-05 23.8 0.0 0.00011 22.8 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Ku_N PF03731.15 GAN08502.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain MAD PF05557.13 GAN08503.1 - 3.3e-05 22.5 55.1 0.0036 15.8 19.7 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein KASH_CCD PF14662.6 GAN08503.1 - 0.0034 17.2 25.1 0.0034 17.2 25.1 3.2 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH LIFR_D2 PF17971.1 GAN08503.1 - 0.14 12.3 1.7 0.23 11.7 0.2 2.1 2 1 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain DUF5595 PF18077.1 GAN08503.1 - 0.22 11.6 0.2 0.22 11.6 0.2 5.4 5 1 2 7 7 7 0 Domain of unknown function (DUF5595) Lebercilin PF15619.6 GAN08503.1 - 0.29 10.8 67.2 0.16 11.6 26.5 3.5 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Vac_Fusion PF02346.16 GAN08503.1 - 0.67 9.6 16.1 0.68 9.6 0.5 4.8 4 1 1 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 Filament PF00038.21 GAN08503.1 - 1.6 8.2 55.0 0.03 13.9 21.8 3.2 1 1 2 3 3 3 0 Intermediate filament protein ATG16 PF08614.11 GAN08503.1 - 2.1 8.5 64.1 1.5 9.0 16.2 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 GAN08503.1 - 3.3 5.7 59.7 9.7 4.2 59.7 1.8 1 1 0 1 1 1 0 HOOK protein GAS PF13851.6 GAN08503.1 - 5.7 6.2 59.7 0.32 10.3 24.1 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 GAN08503.1 - 7.6 6.9 53.8 12 6.3 12.8 3.6 1 1 2 3 3 3 0 Fez1 CENP-F_leu_zip PF10473.9 GAN08503.1 - 7.9 6.5 64.1 0.57 10.2 25.9 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 GAN08503.1 - 8.2 6.5 20.5 5.4 7.0 0.5 5.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat ERM PF00769.19 GAN08503.1 - 8.8 6.1 53.4 0.48 10.2 19.4 3.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.9 GAN08504.1 - 0.28 11.5 1.4 0.77 10.1 0.3 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HARE-HTH PF05066.13 GAN08505.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Metallophos PF00149.28 GAN08506.1 - 1.8e-16 61.3 0.8 4.2e-16 60.1 0.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAN08506.1 - 2.6e-07 31.4 2.3 1.1e-06 29.4 0.2 3.1 4 0 0 4 4 4 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAN08506.1 - 0.0046 17.5 0.5 0.011 16.3 0.5 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Snurportin1 PF11538.8 GAN08507.1 - 0.11 12.7 7.9 0.25 11.6 7.9 1.6 1 0 0 1 1 1 0 Snurportin1 Myosin_head PF00063.21 GAN08510.1 - 9.7e-273 906.4 10.8 9.7e-273 906.4 10.8 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 GAN08510.1 - 3.3e-08 33.2 3.4 1.2e-07 31.4 3.4 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Lebercilin PF15619.6 GAN08510.1 - 4.5e-05 23.2 16.7 4.5e-05 23.2 16.7 3.2 2 1 1 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 GAN08510.1 - 0.00021 21.5 14.0 0.00021 21.5 14.0 5.7 3 1 2 5 5 5 1 Fibrinogen alpha/beta chain family AAA_19 PF13245.6 GAN08510.1 - 0.013 15.9 0.0 0.013 15.9 0.0 2.3 2 1 0 2 2 1 0 AAA domain Filament PF00038.21 GAN08510.1 - 0.062 12.9 49.9 0.1 12.2 12.9 3.6 1 1 2 3 3 3 0 Intermediate filament protein zf-UBP_var PF17807.1 GAN08510.1 - 0.089 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Variant UBP zinc finger UPF0242 PF06785.11 GAN08510.1 - 0.091 12.9 61.8 0.023 14.8 25.5 3.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus AAA_22 PF13401.6 GAN08510.1 - 0.1 12.9 0.0 0.1 12.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF16 PF01519.16 GAN08510.1 - 0.1 13.1 40.6 3.1 8.3 13.9 5.1 1 1 2 4 4 4 0 Protein of unknown function DUF16 AAA_16 PF13191.6 GAN08510.1 - 0.22 11.9 0.0 0.22 11.9 0.0 3.7 2 1 0 2 2 1 0 AAA ATPase domain DUF4407 PF14362.6 GAN08510.1 - 1.1 8.5 42.7 0.097 12.0 25.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) IQ PF00612.27 GAN08510.1 - 1.7 8.6 6.1 1.1 9.2 1.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif dCMP_cyt_deam_1 PF00383.23 GAN08511.1 - 4e-24 84.4 1.3 6.7e-24 83.7 0.7 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAN08511.1 - 3.1e-13 49.6 0.2 1.5e-12 47.4 0.1 1.9 2 0 0 2 2 2 1 MafB19-like deaminase AAA_18 PF13238.6 GAN08511.1 - 0.0017 18.9 0.0 0.0045 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SNAD4 PF18750.1 GAN08511.1 - 0.038 14.1 0.2 0.077 13.1 0.2 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 GAN08511.1 - 0.081 12.9 0.3 0.38 10.7 0.0 2.1 3 0 0 3 3 3 0 APOBEC4-like -AID/APOBEC-deaminase TFIID_20kDa PF03847.13 GAN08512.1 - 5.2e-35 119.8 0.7 9.9e-35 118.9 0.7 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 GAN08512.1 - 3.5e-05 24.0 0.1 8.2e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAN08512.1 - 0.0001 22.7 0.1 0.0001 22.7 0.1 3.7 3 1 0 4 4 4 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAN08512.1 - 0.0037 17.3 0.0 0.0037 17.3 0.0 2.8 2 1 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit DUF5405 PF17399.2 GAN08512.1 - 0.32 11.3 3.7 10 6.5 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5405) DUF1515 PF07439.11 GAN08512.1 - 2.2 8.3 5.0 31 4.6 1.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Pkinase PF00069.25 GAN08513.1 - 4.7e-62 209.7 0.0 7.5e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08513.1 - 7.8e-26 90.9 0.0 1.1e-25 90.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN08513.1 - 0.00031 20.2 0.1 0.00067 19.1 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN08513.1 - 0.064 12.2 0.2 0.096 11.6 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CPSase_L_D2 PF02786.17 GAN08514.1 - 1.3e-71 240.5 0.0 2.4e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAN08514.1 - 8.5e-44 148.6 0.0 2.2e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN08514.1 - 7.7e-31 106.4 0.0 6.8e-30 103.3 0.0 2.5 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAN08514.1 - 1.2e-16 60.3 2.2 2.8e-16 59.1 2.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 GAN08514.1 - 9.3e-14 51.9 0.0 2.8e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl_2 PF13533.6 GAN08514.1 - 4.7e-08 32.7 0.5 0.00033 20.4 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAN08514.1 - 4.3e-07 29.7 0.1 1.3e-06 28.1 0.1 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_D23 PF16576.5 GAN08514.1 - 4.8e-05 22.7 0.8 0.17 11.1 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp PF02222.22 GAN08514.1 - 0.00012 21.7 0.0 0.00037 20.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 GAN08514.1 - 0.0018 19.0 0.7 0.15 12.8 0.0 3.2 4 0 0 4 4 4 1 HlyD family secretion protein PTS_EIIA_1 PF00358.20 GAN08514.1 - 0.11 12.2 0.3 6.3 6.6 0.1 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF1681 PF07933.14 GAN08514.1 - 0.22 11.2 0.8 2.7 7.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1681) Tim44 PF04280.15 GAN08516.1 - 2.1e-36 125.2 1.3 2.9e-36 124.8 0.1 1.9 2 0 0 2 2 2 1 Tim44-like domain T4SS PF07996.11 GAN08516.1 - 0.015 15.7 5.4 0.034 14.5 5.4 1.5 1 0 0 1 1 1 0 Type IV secretion system proteins HutD PF05962.11 GAN08516.1 - 0.038 14.0 0.2 0.09 12.7 0.2 1.6 1 0 0 1 1 1 0 HutD Arc_PepC PF06819.11 GAN08516.1 - 0.047 13.8 11.1 3.7 7.7 0.2 3.9 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain CHAD PF05235.14 GAN08516.1 - 1.5 8.7 6.7 3.8 7.4 6.4 1.6 1 1 0 1 1 1 0 CHAD domain SbsC_C PF18058.1 GAN08516.1 - 4.5 7.5 17.7 1.5 9.1 7.7 2.4 2 0 0 2 2 2 0 SbsC C-terminal domain UEV PF05743.13 GAN08517.1 - 1.2e-37 128.5 0.2 2.4e-37 127.5 0.2 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 GAN08517.1 - 2e-26 91.7 0.4 4.4e-26 90.6 0.4 1.6 1 0 0 1 1 1 1 Vps23 core domain cNMP_binding PF00027.29 GAN08518.1 - 2.4e-31 107.6 0.0 1.7e-16 60.1 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 GAN08518.1 - 2.1e-17 64.0 5.0 1.7e-16 61.0 5.0 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase zf-C2H2_6 PF13912.6 GAN08519.1 - 0.0016 18.4 4.2 0.0031 17.5 4.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger SR-25 PF10500.9 GAN08519.1 - 0.025 14.2 13.3 0.037 13.6 13.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CNDH2_C PF16858.5 GAN08519.1 - 0.084 12.7 9.1 0.13 12.2 9.1 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-C2H2 PF00096.26 GAN08519.1 - 0.11 13.1 5.8 0.2 12.2 3.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GAN08519.1 - 1.2 9.0 4.0 6.3 6.7 0.7 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 GAN08519.1 - 5.5 8.1 7.1 4.4 8.4 4.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2781 PF10914.8 GAN08520.1 - 0.029 14.8 1.3 5.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2781) TMEM135_C_rich PF15982.5 GAN08520.1 - 0.04 14.5 2.2 0.073 13.7 0.2 2.4 3 0 0 3 3 3 0 N-terminal cysteine-rich region of Transmembrane protein 135 ABC_tran PF00005.27 GAN08521.1 - 6.4e-16 59.1 0.0 2e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAN08521.1 - 4.1e-11 43.2 2.1 6.8e-05 22.8 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 GAN08521.1 - 0.0099 16.0 0.1 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAN08521.1 - 0.013 15.8 0.4 0.024 14.9 0.1 1.6 2 0 0 2 2 1 0 AAA domain DUF3584 PF12128.8 GAN08521.1 - 0.013 13.1 0.2 0.018 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_29 PF13555.6 GAN08521.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 GAN08521.1 - 0.016 14.7 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 GAN08521.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAN08521.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 GAN08521.1 - 0.021 15.3 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAN08521.1 - 0.026 14.1 0.2 0.057 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 GAN08521.1 - 0.05 13.1 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.12 GAN08521.1 - 0.052 13.5 0.3 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 GAN08521.1 - 0.052 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 GAN08521.1 - 0.054 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAN08521.1 - 0.097 12.9 0.7 0.42 10.9 0.7 2.0 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 GAN08521.1 - 0.099 12.9 0.0 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAN08521.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAN08521.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 GAN08521.1 - 0.15 11.4 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 GAN08521.1 - 0.15 11.7 0.2 0.23 11.1 0.2 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 GAN08521.1 - 0.15 10.6 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAN08521.1 - 0.15 11.7 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAN08521.1 - 0.17 12.4 0.5 0.46 11.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain Ribosomal_S5_C PF03719.15 GAN08522.1 - 5.3e-28 96.3 0.0 8.7e-27 92.4 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GAN08522.1 - 1.8e-22 79.1 2.2 2.9e-22 78.4 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Fer4 PF00037.27 GAN08523.1 - 8.2e-15 53.9 15.4 1.7e-08 33.9 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GAN08523.1 - 6.7e-13 49.0 10.8 1.1e-12 48.3 10.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 GAN08523.1 - 3.1e-10 40.0 4.2 8.1e-05 22.7 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAN08523.1 - 3.3e-10 40.8 7.0 6.6e-05 23.8 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 GAN08523.1 - 3.2e-09 37.1 0.9 0.00036 20.9 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAN08523.1 - 1.2e-08 35.0 21.7 3e-06 27.2 12.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAN08523.1 - 1.2e-08 34.9 10.5 2.1e-08 34.2 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAN08523.1 - 2.2e-07 30.5 11.5 0.0022 18.0 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 GAN08523.1 - 3.7e-07 29.9 17.8 0.00038 20.4 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GAN08523.1 - 1.3e-05 25.3 12.1 0.00048 20.4 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GAN08523.1 - 0.00014 22.3 10.8 0.031 14.8 12.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 GAN08523.1 - 0.00036 21.0 9.9 0.082 13.5 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 GAN08523.1 - 0.0062 16.7 8.5 0.24 11.6 0.4 3.2 2 2 2 4 4 4 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 GAN08523.1 - 0.0063 16.6 3.6 0.14 12.3 0.2 2.3 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 GAN08523.1 - 0.014 15.6 8.5 7.2 6.8 8.2 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 GAN08523.1 - 0.19 12.8 16.3 0.33 12.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 GAN08523.1 - 0.41 11.5 11.7 3.2 8.7 2.1 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Ribonucleas_3_3 PF14622.6 GAN08524.1 - 2e-19 70.0 0.2 4e-19 69.0 0.1 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAN08524.1 - 0.052 14.2 0.0 1.1 9.9 0.0 2.3 1 1 0 1 1 1 0 Ribonuclease III domain SWIRM PF04433.17 GAN08525.1 - 4.7e-30 103.8 3.7 6.8e-30 103.3 0.0 3.1 3 0 0 3 3 3 1 SWIRM domain SWIRM-assoc_2 PF16496.5 GAN08525.1 - 1.4e-27 96.7 14.7 1.4e-27 96.7 14.7 2.8 2 1 0 2 2 2 1 SWIRM-associated domain at the N-terminal Myb_DNA-binding PF00249.31 GAN08525.1 - 7.8e-13 48.4 0.0 1.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN08525.1 - 1.1e-06 28.7 1.2 5.2e-06 26.6 0.0 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 GAN08525.1 - 1.4e-06 28.2 2.0 1.4e-06 28.2 2.0 2.9 2 1 1 3 3 3 1 SWIRM-associated region 1 THOC7 PF05615.13 GAN08525.1 - 0.00041 20.6 4.8 0.00041 20.6 4.8 2.3 2 0 0 2 2 2 1 Tho complex subunit 7 BRCT_2 PF16589.5 GAN08525.1 - 0.02 15.3 0.6 0.32 11.4 0.6 2.6 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain FtsJ PF01728.19 GAN08526.1 - 2.1e-68 229.9 0.0 2.5e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase SF3b10 PF07189.11 GAN08527.1 - 1e-38 131.3 0.0 1.1e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Fungal_trans PF04082.18 GAN08528.1 - 8.7e-23 80.7 0.1 8.7e-23 80.7 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN08528.1 - 4.5e-12 45.9 12.9 7.5e-12 45.2 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain THF_DHG_CYH PF00763.23 GAN08528.1 - 0.019 15.2 1.9 0.027 14.7 0.1 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CBS PF00571.28 GAN08529.1 - 4.3e-27 94.3 1.3 4.1e-06 27.2 0.1 4.6 4 1 0 4 4 4 4 CBS domain Peptidase_M48 PF01435.18 GAN08530.1 - 2e-37 128.9 0.0 3.3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Aminopep PF10023.9 GAN08530.1 - 0.024 14.0 0.9 5.2 6.3 0.1 3.3 3 0 0 3 3 3 0 Putative aminopeptidase SNF2_N PF00176.23 GAN08532.1 - 9.2e-46 156.2 0.2 1.6e-45 155.3 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN08532.1 - 5.4e-16 58.9 0.0 1.8e-15 57.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN08532.1 - 3.6e-08 33.6 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAN08532.1 - 5.3e-07 29.1 0.1 2e-06 27.2 0.0 1.9 1 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 GAN08532.1 - 0.00015 21.5 0.0 0.044 13.4 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase AAA_14 PF13173.6 GAN08532.1 - 0.0021 18.1 0.8 0.012 15.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain Ser_hydrolase PF06821.13 GAN08532.1 - 0.078 12.8 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase LRAT PF04970.13 GAN08533.1 - 0.075 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase RVT_1 PF00078.27 GAN08534.1 - 3.1e-20 72.7 0.0 4.6e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sel1 PF08238.12 GAN08535.1 - 3e-118 383.6 68.9 1.4e-10 41.5 0.1 16.1 16 0 0 16 16 16 14 Sel1 repeat TPR_6 PF13174.6 GAN08535.1 - 0.00085 19.8 7.8 0.46 11.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat GSu_C4xC__C2xCH PF09698.10 GAN08535.1 - 0.054 14.3 0.9 0.054 14.3 0.9 4.7 5 0 0 5 5 5 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) pP_pnuc_1 PF18165.1 GAN08535.1 - 0.11 12.4 0.4 99 2.8 0.0 4.6 3 1 2 5 5 5 0 Predicted pPIWI-associating nuclease Fib_succ_major PF09603.10 GAN08535.1 - 0.77 10.4 7.2 4.3e+02 1.4 0.0 4.3 1 1 2 3 3 3 0 Fibrobacter succinogenes major domain (Fib_succ_major) TPR_16 PF13432.6 GAN08535.1 - 7.6 7.3 16.7 1.7 9.4 0.3 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_membrane PF00664.23 GAN08536.1 - 8.1e-53 179.8 31.8 2.8e-32 112.5 10.5 3.5 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN08536.1 - 4.2e-45 153.6 0.0 8.9e-29 100.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN08536.1 - 2e-06 27.4 6.2 0.0059 16.1 0.3 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 GAN08536.1 - 2.1e-05 24.2 0.0 0.018 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAN08536.1 - 0.00015 21.0 0.0 0.16 11.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 GAN08536.1 - 0.00055 20.2 0.2 0.97 9.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAN08536.1 - 0.0043 16.8 1.6 0.57 10.0 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 GAN08536.1 - 0.0044 17.1 1.5 0.26 11.3 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain ATPase PF06745.13 GAN08536.1 - 0.0067 15.8 0.1 1.1 8.5 0.0 2.4 2 0 0 2 2 2 1 KaiC ResIII PF04851.15 GAN08536.1 - 0.0069 16.4 0.0 0.41 10.6 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 GAN08536.1 - 0.0074 15.8 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 GAN08536.1 - 0.028 13.6 0.6 0.62 9.2 0.2 3.2 4 1 0 4 4 4 0 NB-ARC domain AAA_23 PF13476.6 GAN08536.1 - 0.036 14.6 0.5 5.3 7.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAN08536.1 - 0.046 13.1 1.1 4.7 6.5 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 GAN08536.1 - 0.066 13.6 0.1 1.4 9.3 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 GAN08536.1 - 0.073 12.9 1.6 4.5 7.0 0.0 2.9 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Pox_A32 PF04665.12 GAN08536.1 - 0.11 12.0 0.5 4.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.29 GAN08536.1 - 0.11 12.2 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 GAN08536.1 - 0.14 11.3 0.8 4.3 6.5 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 GAN08536.1 - 0.16 11.7 0.1 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAN08536.1 - 0.19 11.8 0.2 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase XPG_N PF00752.17 GAN08537.1 - 5.6e-38 129.5 0.1 1.4e-37 128.2 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 GAN08537.1 - 1.2e-31 108.9 0.1 3.7e-31 107.3 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 GAN08537.1 - 1.2e-05 25.8 0.0 3.5e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TFR_dimer PF04253.15 GAN08538.1 - 2.8e-21 75.8 0.2 8.3e-21 74.3 0.2 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAN08538.1 - 1.4e-17 64.1 0.4 6.2e-17 61.9 0.2 2.1 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 GAN08538.1 - 7.1e-09 35.6 0.0 1.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 PA domain ATG16 PF08614.11 GAN08538.1 - 0.22 11.7 2.5 0.46 10.7 1.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_19 PF14559.6 GAN08539.1 - 0.068 13.7 0.1 0.084 13.4 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5038 PF16441.5 GAN08539.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) Pkinase_Tyr PF07714.17 GAN08540.1 - 1.4e-17 63.9 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAN08540.1 - 5.6e-15 55.4 0.0 1.7e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain HECT PF00632.25 GAN08541.1 - 2.3e-84 283.5 0.4 8.5e-84 281.6 0.1 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PAPA-1 PF04795.12 GAN08542.1 - 2.5e-20 73.0 10.0 2.5e-20 73.0 10.0 3.3 2 1 1 3 3 3 1 PAPA-1-like conserved region zf-HIT PF04438.16 GAN08542.1 - 0.37 10.7 1.7 0.51 10.3 1.7 1.2 1 0 0 1 1 1 0 HIT zinc finger SDA1 PF05285.12 GAN08542.1 - 0.84 9.0 48.4 1.3 8.4 48.4 1.2 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 GAN08542.1 - 3.2 5.7 18.5 4.9 5.1 18.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3037 PF11236.8 GAN08543.1 - 0.0024 18.3 0.1 0.012 16.0 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3037) 6PF2K PF01591.18 GAN08544.1 - 5.2e-84 281.0 1.0 7.1e-84 280.6 1.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAN08544.1 - 3.9e-34 118.1 0.0 5.9e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAN08544.1 - 6.3e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Phage_fiber_2 PF03406.13 GAN08544.1 - 0.083 12.5 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Phage tail fibre repeat Fungal_trans PF04082.18 GAN08545.1 - 1.3e-20 73.6 5.0 2.3e-20 72.7 5.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN08545.1 - 2.4e-10 40.3 8.4 5.5e-10 39.2 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E2F_TDP PF02319.20 GAN08546.1 - 1.6e-23 82.5 0.4 3.3e-23 81.5 0.4 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 GAN08546.1 - 6.3e-06 26.1 1.3 1.8e-05 24.6 1.3 1.8 1 0 0 1 1 1 1 Transcription factor DP Strep_pep PF14404.6 GAN08546.1 - 0.13 12.5 0.1 11 6.4 0.0 3.2 2 1 1 3 3 3 0 Ribosomally synthesized peptide in Streptomyces species PPR_2 PF13041.6 GAN08547.1 - 1.8e-58 194.5 24.9 2.5e-11 43.6 0.0 16.5 14 4 4 18 18 16 10 PPR repeat family PPR PF01535.20 GAN08547.1 - 1.1e-44 147.6 19.5 0.00051 20.1 0.0 20.4 21 1 0 21 21 19 9 PPR repeat PPR_3 PF13812.6 GAN08547.1 - 3.3e-33 113.6 17.6 1.1e-08 35.0 0.1 12.7 9 4 5 16 16 16 6 Pentatricopeptide repeat domain PPR_long PF17177.4 GAN08547.1 - 1.4e-29 103.0 16.9 4e-09 36.1 0.5 8.5 3 2 5 8 8 8 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAN08547.1 - 1.5e-18 66.1 15.0 0.037 13.7 0.0 14.8 18 0 0 18 18 17 4 PPR repeat TPR_19 PF14559.6 GAN08547.1 - 1.4e-11 44.7 0.9 0.14 12.7 0.1 7.4 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN08547.1 - 3.4e-09 36.7 0.0 89 4.3 0.0 10.2 10 2 2 12 12 8 0 Tetratricopeptide repeat ATP13 PF12921.7 GAN08547.1 - 5.2e-06 26.3 5.3 5.6 6.9 0.0 8.6 7 2 2 10 10 10 1 Mitochondrial ATPase expression TPR_8 PF13181.6 GAN08547.1 - 8.7e-06 25.6 10.4 1.7 9.1 0.1 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat RPM2 PF08579.11 GAN08547.1 - 2.8e-05 24.5 2.0 0.06 13.7 0.0 5.1 5 0 0 5 5 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_2 PF07719.17 GAN08547.1 - 0.00073 19.5 7.3 35 4.9 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAN08547.1 - 0.00079 18.7 10.2 0.0038 16.5 0.8 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN08547.1 - 0.0031 17.8 10.4 3.6 7.9 0.2 6.7 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAN08547.1 - 0.0034 17.1 5.2 20 5.2 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN08547.1 - 0.0072 16.9 4.2 1.6e+02 3.2 0.0 8.3 10 0 0 10 10 8 0 Tetratricopeptide repeat PrkA PF06798.12 GAN08547.1 - 0.056 13.1 3.3 0.35 10.4 0.7 2.7 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain Mad3_BUB1_I PF08311.12 GAN08547.1 - 0.092 12.7 6.6 4.7 7.2 0.0 4.0 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 NADH_u_ox_C PF12853.7 GAN08547.1 - 0.34 10.9 1.8 0.65 10.0 0.1 2.3 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Clathrin PF00637.20 GAN08547.1 - 9.9 6.0 14.7 17 5.3 0.1 6.1 7 1 0 7 7 5 0 Region in Clathrin and VPS MFS_1 PF07690.16 GAN08549.1 - 2.7e-46 158.1 19.8 3.5e-46 157.8 19.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN08549.1 - 3.3e-11 42.7 11.8 3.3e-11 42.7 11.8 2.2 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAN08549.1 - 2.2e-09 36.3 8.6 3.1e-09 35.8 8.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAN08549.1 - 0.00027 19.4 5.5 0.00027 19.4 5.5 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 GAN08549.1 - 0.0022 16.5 5.2 0.0038 15.7 5.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 GAN08549.1 - 0.26 10.1 15.7 0.33 9.8 9.4 3.1 2 1 1 3 3 3 0 MFS_1 like family PIP5K PF01504.18 GAN08550.1 - 8.4e-98 326.9 3.2 1.3e-97 326.4 3.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Adaptin_N PF01602.20 GAN08551.1 - 9.7e-12 44.2 0.2 1.5e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 Adaptin N terminal region FOXP-CC PF16159.5 GAN08551.1 - 3.2e-06 27.7 3.5 0.008 16.8 0.3 2.8 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 GAN08551.1 - 1.6e-05 25.1 2.1 0.12 12.9 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN08551.1 - 0.061 14.2 4.8 0.64 11.0 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger CDC45 PF02724.14 GAN08551.1 - 0.16 10.2 9.6 0.28 9.4 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein zf_ZIC PF18366.1 GAN08551.1 - 0.18 11.9 0.1 0.58 10.3 0.0 1.9 2 0 0 2 2 1 0 Zic proteins zinc finger domain CobT PF06213.12 GAN08551.1 - 0.21 11.0 15.8 1.4 8.3 16.2 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT CDC27 PF09507.10 GAN08551.1 - 0.21 11.0 23.0 0.0059 16.1 14.1 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Prothymosin PF03247.14 GAN08551.1 - 0.36 11.3 20.5 0.052 14.0 16.2 1.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family NOA36 PF06524.12 GAN08551.1 - 1.4 8.2 14.4 3.2 7.0 14.4 1.6 1 0 0 1 1 1 0 NOA36 protein DUF1079 PF06435.11 GAN08551.1 - 2.2 8.6 0.0 2.2 8.6 0.0 4.6 6 0 0 6 6 4 0 Repeat of unknown function (DUF1079) Bac_chlorC PF02043.17 GAN08551.1 - 3.6 7.7 13.8 0.34 10.9 0.7 4.2 4 1 1 5 5 5 0 Bacteriochlorophyll C binding protein Zap1_zf2 PF18217.1 GAN08551.1 - 7.6 6.6 7.5 23 5.1 1.4 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 Adaptin_N PF01602.20 GAN08552.1 - 9.8e-18 64.0 0.3 9.2e-09 34.4 0.1 3.1 1 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 GAN08552.1 - 1.8e-11 44.4 0.8 2.8e-10 40.5 0.0 2.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Hexokinase_2 PF03727.16 GAN08554.1 - 1.3e-67 227.7 0.0 1.7e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN08554.1 - 2.1e-47 161.6 0.0 3.2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase NTF2 PF02136.20 GAN08555.1 - 2.3e-30 105.6 0.2 2.3e-30 105.6 0.2 2.2 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAN08555.1 - 5.1e-10 39.0 0.1 5.1e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C14 PF00656.22 GAN08556.1 - 2.7e-53 181.4 0.2 6.5e-53 180.2 0.0 1.7 2 0 0 2 2 2 1 Caspase domain Snf7 PF03357.21 GAN08556.1 - 3.5e-22 78.8 7.1 6.4e-22 78.0 7.1 1.4 1 0 0 1 1 1 1 Snf7 GrpE PF01025.19 GAN08556.1 - 0.13 12.0 4.2 0.37 10.5 4.2 1.8 1 0 0 1 1 1 0 GrpE NPV_P10 PF05531.12 GAN08556.1 - 2.2 8.8 4.6 42 4.7 0.0 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ELO PF01151.18 GAN08558.1 - 8.6e-47 159.8 22.6 1.1e-46 159.4 22.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CTP_transf_like PF01467.26 GAN08559.1 - 3.3e-07 30.6 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like CN_hydrolase PF00795.22 GAN08560.1 - 1.1e-14 54.5 0.0 5.3e-14 52.2 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SAP PF02037.27 GAN08560.1 - 3.2e-11 42.7 1.5 6.6e-11 41.7 1.1 1.8 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 GAN08560.1 - 3.6e-05 23.5 14.5 0.0019 17.9 3.0 4.1 3 1 0 3 3 3 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 GAN08560.1 - 0.23 11.2 1.8 0.61 9.9 0.8 2.1 2 0 0 2 2 2 0 HeH/LEM domain TipE PF16972.5 GAN08560.1 - 0.76 8.9 6.8 1.4 8.0 6.8 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Kelch_6 PF13964.6 GAN08562.1 - 6.4e-19 67.5 12.5 9.1e-05 22.6 0.1 6.7 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAN08562.1 - 2e-17 62.9 14.0 2.3e-05 24.3 0.1 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN08562.1 - 7e-16 57.8 13.8 0.001 19.0 0.1 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GAN08562.1 - 2.7e-14 52.5 7.0 0.00035 20.4 0.1 7.0 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.25 GAN08562.1 - 4.5e-11 42.1 7.0 7.9e-05 22.2 0.0 5.4 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 GAN08562.1 - 4.3e-10 39.6 15.8 0.061 13.6 0.0 6.6 5 1 1 6 6 6 3 Galactose oxidase, central domain ASC PF00858.24 GAN08562.1 - 0.0012 17.9 2.7 0.14 11.1 0.0 3.2 3 0 0 3 3 3 1 Amiloride-sensitive sodium channel Glyoxal_oxid_N PF07250.11 GAN08562.1 - 0.0092 15.2 0.1 0.063 12.5 0.0 2.2 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus YqhR PF11085.8 GAN08562.1 - 0.025 14.5 0.1 0.025 14.5 0.1 1.8 3 0 0 3 3 3 0 Conserved membrane protein YqhR RCC1_2 PF13540.6 GAN08562.1 - 0.063 13.1 0.2 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat DUF5122 PF17164.4 GAN08562.1 - 0.096 13.0 1.1 1.5 9.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller VSP PF03302.13 GAN08562.1 - 1.7 7.4 3.5 0.97 8.2 0.9 1.8 2 0 0 2 2 2 0 Giardia variant-specific surface protein WD40 PF00400.32 GAN08563.1 - 6.5e-37 124.9 16.7 4.9e-08 33.5 0.2 7.3 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08563.1 - 5.4e-05 23.4 2.2 3.2 8.1 0.1 5.1 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AP-5_subunit_s1 PF15001.6 GAN08563.1 - 0.009 16.0 1.5 0.016 15.2 1.5 1.3 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 Nup160 PF11715.8 GAN08563.1 - 0.021 13.5 0.7 8.7 4.9 0.2 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 GAN08563.1 - 0.033 13.5 0.0 0.24 10.7 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain DUF724 PF05266.14 GAN08563.1 - 0.4 10.5 7.2 0.66 9.8 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Pkinase PF00069.25 GAN08564.1 - 4.9e-71 239.2 0.0 9.7e-71 238.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08564.1 - 1.2e-53 182.0 0.0 2.1e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 GAN08564.1 - 3.8e-53 179.4 0.0 7.5e-53 178.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN08564.1 - 4.2e-19 68.9 0.2 1.5e-18 67.2 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN08564.1 - 4.5e-09 36.0 0.0 8.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Kinase-like PF14531.6 GAN08564.1 - 3.1e-06 26.7 0.2 0.00089 18.7 0.0 2.9 1 1 1 3 3 3 1 Kinase-like RsgA_GTPase PF03193.16 GAN08564.1 - 1.6e-05 24.9 0.1 0.036 14.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAN08564.1 - 3.2e-05 23.6 0.0 7.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RIO1 PF01163.22 GAN08564.1 - 0.00094 18.8 0.1 0.0025 17.4 0.1 1.7 1 0 0 1 1 1 1 RIO1 family MMR_HSR1 PF01926.23 GAN08564.1 - 0.023 14.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase YrbL-PhoP_reg PF10707.9 GAN08564.1 - 0.054 13.0 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL pPIWI_RE_Y PF18156.1 GAN08564.1 - 0.057 13.8 0.2 0.3 11.5 0.0 2.3 3 0 0 3 3 2 0 pPIWI_RE three-gene island domain Y VTC PF09359.10 GAN08565.1 - 9.8e-85 284.3 0.5 2.6e-84 282.9 0.0 2.0 3 0 0 3 3 3 1 VTC domain DUF202 PF02656.15 GAN08565.1 - 3.5e-10 40.2 6.3 3.5e-10 40.2 6.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAN08565.1 - 7.8e-07 29.3 29.1 0.00018 21.6 2.0 4.1 2 1 2 4 4 4 2 SPX domain DUF2207 PF09972.9 GAN08565.1 - 0.0066 15.3 0.0 0.048 12.4 0.0 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Glycos_transf_4 PF00953.21 GAN08565.1 - 0.18 11.8 2.8 0.31 11.0 2.8 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 DUF4199 PF13858.6 GAN08565.1 - 0.8 10.1 5.8 3.9 7.9 6.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) ATG13 PF10033.9 GAN08566.1 - 3.8e-41 141.4 0.6 8.6e-41 140.2 0.6 1.6 1 0 0 1 1 1 1 Autophagy-related protein 13 TTC5_OB PF16669.5 GAN08566.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain SIS PF01380.22 GAN08567.1 - 1.5e-63 212.5 0.5 2.1e-33 114.9 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAN08567.1 - 7.3e-17 61.8 0.0 1.5e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAN08567.1 - 1e-12 48.0 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAN08567.1 - 0.00041 19.3 0.0 0.00069 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 GAN08567.1 - 0.0094 16.0 0.0 0.028 14.4 0.0 1.8 2 0 0 2 2 2 1 SIS domain CoA_transf_3 PF02515.17 GAN08568.1 - 1.3e-119 399.7 0.0 7.3e-119 397.2 0.0 1.8 1 1 0 1 1 1 1 CoA-transferase family III CS PF04969.16 GAN08569.1 - 6.7e-11 43.1 0.8 2.2e-10 41.4 0.1 2.1 2 0 0 2 2 2 1 CS domain Parvo_coat_N PF08398.10 GAN08569.1 - 0.2 11.8 0.3 0.58 10.3 0.3 1.7 1 0 0 1 1 1 0 Parvovirus coat protein VP1 RINT1_TIP1 PF04437.13 GAN08570.1 - 6.7e-115 384.8 16.1 6.7e-115 384.8 16.1 2.3 2 1 0 2 2 2 1 RINT-1 / TIP-1 family DSPc PF00782.20 GAN08570.1 - 3.4e-29 101.4 1.0 9.9e-28 96.6 0.1 3.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 GAN08570.1 - 0.012 15.9 0.0 0.076 13.3 0.0 2.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain MFS_1 PF07690.16 GAN08571.1 - 1e-37 129.9 43.4 3.8e-32 111.6 21.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MLANA PF14991.6 GAN08571.1 - 0.17 12.2 0.0 19 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein melan-A RhoGEF PF00621.20 GAN08572.1 - 6.7e-28 98.2 1.8 6.7e-28 98.2 1.8 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF3112 PF11309.8 GAN08572.1 - 0.18 11.2 0.7 0.3 10.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) GHMP_kinases_N PF00288.26 GAN08573.1 - 4.1e-14 52.6 0.6 1.1e-13 51.2 0.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAN08573.1 - 2.2e-07 31.1 0.0 5.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PHD PF00628.29 GAN08574.1 - 1e-08 34.9 14.4 1.9e-08 34.1 14.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAN08574.1 - 0.0029 17.1 9.0 0.0047 16.4 9.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 GAN08574.1 - 0.014 15.4 6.1 0.03 14.3 6.1 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger NIPSNAP PF07978.13 GAN08575.1 - 4.3e-37 126.4 0.2 7.5e-24 83.9 0.1 2.1 2 0 0 2 2 2 2 NIPSNAP CBFD_NFYB_HMF PF00808.23 GAN08576.1 - 4.7e-18 65.2 0.3 9.5e-18 64.2 0.3 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAN08576.1 - 3.4e-06 27.4 0.1 3.4e-06 27.4 0.1 2.6 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Myc_N PF01056.18 GAN08576.1 - 0.018 15.0 12.7 0.022 14.7 12.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Pol_alpha_B_N PF08418.10 GAN08576.1 - 0.84 9.5 17.6 3.3 7.6 17.6 1.9 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SCIMP PF15050.6 GAN08576.1 - 1.7 9.1 4.5 2.2 8.7 3.6 1.6 1 1 0 1 1 1 0 SCIMP protein DUF5427 PF10310.9 GAN08576.1 - 1.8 7.4 19.2 2.5 7.0 19.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Q_salvage PF10343.9 GAN08577.1 - 1.2e-27 97.2 0.0 3.4e-26 92.5 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Ion_trans PF00520.31 GAN08579.1 - 5.4e-107 356.6 74.5 3.7e-30 105.0 19.5 5.0 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 GAN08579.1 - 0.00046 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 GAN08579.1 - 0.0007 18.4 5.0 0.0007 18.4 5.0 6.1 6 0 0 6 6 6 3 Polycystin cation channel NCA2 PF08637.10 GAN08581.1 - 9.2e-87 290.9 3.6 2.3e-86 289.6 3.6 1.6 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Glyco_hydro_18 PF00704.28 GAN08582.1 - 2.9e-74 250.6 2.1 3.8e-74 250.2 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 GAN08582.1 - 7e-05 22.7 4.0 0.00024 21.0 4.0 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) BUD22 PF09073.10 GAN08582.1 - 0.41 9.9 12.5 0.75 9.1 12.5 1.4 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAN08582.1 - 3 6.0 6.2 4.3 5.5 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 GAN08582.1 - 3.1 8.2 8.0 7.4 7.0 8.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 GAN08582.1 - 3.3 6.8 14.4 4.9 6.2 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_RNA_Pol_19 PF05320.12 GAN08582.1 - 5.2 7.0 7.0 9.6 6.1 7.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Zn_clus PF00172.18 GAN08583.1 - 5.4e-09 36.0 6.6 9.9e-09 35.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAN08583.1 - 3.8e-06 26.1 1.7 1.1e-05 24.6 1.7 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain SSP160 PF06933.11 GAN08583.1 - 0.24 9.6 6.3 0.37 8.9 6.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TLD PF07534.16 GAN08584.1 - 2.5e-22 79.6 1.6 4.1e-22 78.9 1.6 1.4 1 0 0 1 1 1 1 TLD Pkinase PF00069.25 GAN08585.1 - 7e-75 251.8 0.0 1.2e-74 251.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08585.1 - 1.9e-40 138.8 0.0 5.8e-40 137.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN08585.1 - 7.8e-05 22.7 0.0 0.0013 18.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN08585.1 - 0.003 16.9 0.0 0.0052 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN08585.1 - 0.02 13.9 0.0 0.02 13.9 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 GAN08585.1 - 0.051 12.9 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAN08585.1 - 0.061 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 GAN08585.1 - 0.099 12.2 0.0 0.099 12.2 0.0 2.2 3 0 0 3 3 3 0 Choline/ethanolamine kinase FHA PF00498.26 GAN08587.1 - 2.3e-14 53.5 0.0 4.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAN08587.1 - 0.0046 17.3 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain E1-E2_ATPase PF00122.20 GAN08589.1 - 2.4e-44 151.0 1.1 2.4e-44 151.0 1.1 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN08589.1 - 1.1e-25 90.4 9.4 3.4e-25 88.8 1.0 3.3 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAN08589.1 - 1.3e-17 64.8 0.7 9e-15 55.5 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN08589.1 - 4.2e-17 62.0 0.0 7.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN08589.1 - 2.2e-15 56.1 0.1 7.2e-14 51.2 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 GAN08589.1 - 0.003 18.0 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN08589.1 - 0.15 11.7 5.8 0.055 13.2 1.0 2.3 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Borrelia_P13 PF05628.12 GAN08589.1 - 0.57 10.1 3.4 0.7 9.8 0.1 2.5 2 0 0 2 2 2 0 Borrelia membrane protein P13 DUF3671 PF12420.8 GAN08589.1 - 4.1 7.5 8.1 6 7.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function SAE2 PF08573.10 GAN08590.1 - 3.7e-05 24.8 2.6 3.7e-05 24.8 2.6 3.5 2 2 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SlyX PF04102.12 GAN08590.1 - 0.0015 19.1 10.4 0.52 11.0 3.6 3.2 1 1 2 3 3 3 2 SlyX KASH_CCD PF14662.6 GAN08590.1 - 0.027 14.3 1.0 0.027 14.3 1.0 2.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH BRE1 PF08647.11 GAN08590.1 - 0.25 11.4 14.8 0.68 10.0 5.5 2.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SseC PF04888.12 GAN08590.1 - 0.28 10.8 3.0 0.46 10.0 3.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family HAUS-augmin3 PF14932.6 GAN08590.1 - 2.1 7.9 15.8 0.21 11.2 6.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 GAN08590.1 - 9.1 6.4 10.4 11 6.2 2.1 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 GAN08590.1 - 9.4 6.1 12.9 1.4 8.7 1.4 3.5 3 1 1 4 4 4 0 Septum formation initiator Raffinose_syn PF05691.12 GAN08591.1 - 6.6e-50 169.7 9.4 4.3e-37 127.3 3.9 3.6 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 GAN08591.1 - 0.00045 19.3 1.1 0.004 16.2 0.2 2.6 2 1 0 2 2 2 1 Melibiase FTH PF01827.27 GAN08592.1 - 0.053 13.3 0.4 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 FTH domain COX6B PF02297.17 GAN08593.1 - 8.3e-16 58.0 4.1 1e-15 57.7 4.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 GAN08593.1 - 0.075 13.0 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like C-terminal domain HALZ PF02183.18 GAN08594.1 - 0.073 13.3 3.3 2.2 8.6 0.4 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Zds_C PF08632.10 GAN08595.1 - 4.4e-25 87.2 1.2 1.3e-24 85.7 1.2 1.8 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term SUIM_assoc PF16619.5 GAN08595.1 - 4.2 7.5 29.5 0.85 9.7 20.3 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RVT_1 PF00078.27 GAN08596.1 - 1.1e-13 51.2 0.1 1.3e-13 51.0 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mg_trans_NIPA PF05653.14 GAN08597.1 - 1.1e-100 336.6 23.5 1.4e-100 336.2 23.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAN08597.1 - 8.8e-08 32.4 11.3 2.6e-07 30.9 7.8 4.1 3 1 1 4 4 4 3 EamA-like transporter family Phage_holin_1 PF04531.13 GAN08597.1 - 7.3 7.2 10.7 2 9.0 0.4 4.0 2 1 4 6 6 6 0 Bacteriophage holin Aldo_ket_red PF00248.21 GAN08598.1 - 1.9e-06 27.3 0.0 2.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BicD PF09730.9 GAN08599.1 - 0.28 9.6 41.5 0.035 12.6 28.5 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D TACC_C PF05010.14 GAN08599.1 - 7.8 6.2 44.7 0.31 10.8 22.3 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NTP_transferase PF00483.23 GAN08601.1 - 7.8e-19 68.2 0.0 1.4e-18 67.4 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 GAN08601.1 - 1.7e-09 38.2 0.0 2.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_hydro_8 PF01270.17 GAN08603.1 - 2.2e-20 72.8 0.7 4.2e-20 71.9 0.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 MPLKIP PF15502.6 GAN08604.1 - 0.0064 16.7 2.5 0.0068 16.6 1.8 1.7 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein DUF5320 PF17253.2 GAN08604.1 - 0.07 14.2 10.1 0.09 13.9 10.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5320) FoP_duplication PF13865.6 GAN08604.1 - 2.5 8.7 20.1 4.7 7.8 20.1 1.5 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 LSM PF01423.22 GAN08605.1 - 5.9e-11 41.9 0.1 8.7e-11 41.4 0.1 1.3 1 0 0 1 1 1 1 LSM domain Septin PF00735.18 GAN08606.1 - 7.7e-112 373.2 0.3 9.4e-112 372.9 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN08606.1 - 3.3e-09 36.8 0.2 3.2e-08 33.6 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN08606.1 - 5.2e-07 29.7 0.5 2.7e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 GAN08606.1 - 3.8e-06 26.4 0.0 7.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 GAN08606.1 - 4.1e-05 23.2 0.1 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAN08606.1 - 0.00022 21.7 0.2 0.0013 19.1 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 GAN08606.1 - 0.00043 20.4 0.8 0.77 9.8 0.4 2.5 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 GAN08606.1 - 0.001 18.3 0.8 0.0018 17.6 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain Gtr1_RagA PF04670.12 GAN08606.1 - 0.0018 17.7 0.2 0.028 13.7 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 GAN08606.1 - 0.0034 17.4 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAN08606.1 - 0.004 16.7 0.0 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 GAN08606.1 - 0.0048 17.2 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAN08606.1 - 0.0056 17.2 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 GAN08606.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.13 GAN08606.1 - 0.0068 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Roc PF08477.13 GAN08606.1 - 0.0077 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAN08606.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 GAN08606.1 - 0.027 13.7 0.5 0.34 10.0 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Ras PF00071.22 GAN08606.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Ras family T2SSE PF00437.20 GAN08606.1 - 0.064 12.3 0.2 0.19 10.7 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein RuvB_N PF05496.12 GAN08606.1 - 0.079 12.7 0.1 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 GAN08606.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.13 GAN08606.1 - 0.095 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 GAN08606.1 - 0.098 12.8 0.3 0.4 10.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAN08606.1 - 0.19 11.4 0.1 0.61 9.8 0.0 1.9 3 0 0 3 3 2 0 AAA domain HisG PF01634.18 GAN08607.1 - 9.2e-55 185.0 0.3 1.2e-54 184.6 0.3 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GAN08607.1 - 1.6e-27 95.4 0.3 3.7e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 GAN08607.1 - 1.4e-05 25.1 0.1 1.9e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like DUF1697 PF08002.11 GAN08607.1 - 0.11 12.9 0.0 0.53 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) UreF PF01730.16 GAN08608.1 - 3.6e-22 79.4 0.1 5.7e-22 78.7 0.0 1.3 2 0 0 2 2 2 1 UreF Mito_carr PF00153.27 GAN08610.1 - 4.5e-60 199.6 2.2 1.8e-19 69.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 GAN08611.1 - 2.4e-06 27.5 9.7 2.4e-06 27.5 9.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAN08611.1 - 0.00037 20.5 0.1 0.0013 18.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold TFIIA PF03153.13 GAN08611.1 - 0.012 15.7 13.5 0.017 15.2 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.13 GAN08611.1 - 0.014 14.7 11.6 0.022 14.0 11.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MAP65_ASE1 PF03999.12 GAN08611.1 - 7.2 5.2 13.3 12 4.4 13.3 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DPBB_1 PF03330.18 GAN08612.1 - 6.9e-09 35.9 0.0 9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Ribosomal_L13 PF00572.18 GAN08613.1 - 2e-09 37.7 0.0 1e-07 32.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 TMF_TATA_bd PF12325.8 GAN08614.1 - 0.27 11.4 24.4 0.11 12.8 1.2 3.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding RB_A PF01858.17 GAN08614.1 - 0.33 10.7 10.3 0.033 14.0 3.1 2.6 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain Zein-binding PF04576.15 GAN08614.1 - 2.1 8.7 11.3 1.3 9.3 6.2 3.0 1 1 1 2 2 2 0 Zein-binding DUF4200 PF13863.6 GAN08614.1 - 5.2 7.5 35.1 1.3 9.4 14.3 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Halogen_Hydrol PF10112.9 GAN08614.1 - 9.9 6.1 13.6 0.25 11.3 1.9 2.9 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Velvet PF11754.8 GAN08616.1 - 2.9e-42 145.4 0.0 4e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Phytochelatin PF05023.14 GAN08617.1 - 2.5e-64 216.4 0.0 3.4e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Ribosomal_L22 PF00237.19 GAN08618.1 - 9e-39 131.9 0.1 1.2e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Velvet PF11754.8 GAN08619.1 - 5e-19 69.2 0.9 5e-19 69.2 0.9 2.5 2 1 0 2 2 2 1 Velvet factor Androgen_recep PF02166.16 GAN08619.1 - 4.5 6.0 17.0 0.77 8.5 5.7 2.2 2 0 0 2 2 2 0 Androgen receptor Pkinase PF00069.25 GAN08620.1 - 3.8e-70 236.3 0.0 4.6e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08620.1 - 4.1e-34 118.1 0.0 5.5e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GAN08620.1 - 0.00028 20.6 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 GAN08620.1 - 0.0021 17.4 0.1 0.13 11.5 0.0 2.6 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAN08620.1 - 0.013 14.5 0.0 0.1 11.5 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Forkhead PF00250.18 GAN08621.1 - 1.1e-33 115.3 0.1 1.9e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain ADP_ribosyl_GH PF03747.14 GAN08622.1 - 1.3e-48 166.2 0.0 1.9e-48 165.7 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase zf-C3HC4 PF00097.25 GAN08623.1 - 0.042 13.7 0.7 0.042 13.7 0.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WSD PF15613.6 GAN08623.1 - 0.052 14.0 2.1 1.1 9.7 0.6 3.4 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Ish1 PF10281.9 GAN08623.1 - 0.083 13.2 0.6 0.64 10.4 0.1 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein zf-4CXXC_R1 PF10497.9 GAN08623.1 - 0.31 11.3 11.5 1.3 9.2 11.5 2.0 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 CbtB PF09489.10 GAN08624.1 - 0.62 10.2 0.3 0.62 10.2 0.3 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Pkinase PF00069.25 GAN08625.1 - 2.7e-74 249.9 0.0 4.4e-74 249.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08625.1 - 8.2e-39 133.4 0.0 1.3e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN08625.1 - 3.8e-05 23.7 0.0 0.007 16.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN08625.1 - 0.0062 15.9 0.0 0.091 12.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 GAN08625.1 - 0.054 13.1 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase IBR PF01485.21 GAN08626.1 - 4.1e-09 36.5 21.8 1.5e-07 31.6 10.9 4.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 GAN08626.1 - 0.013 15.8 8.8 0.013 15.8 8.8 5.2 4 1 1 5 5 5 0 Ring finger domain DUF2208 PF09973.9 GAN08626.1 - 0.047 13.3 2.2 0.086 12.4 2.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DPM3 PF08285.11 GAN08626.1 - 9.3 6.5 6.3 4.2 7.6 2.4 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DcpS_C PF11969.8 GAN08627.1 - 8.2e-28 97.2 0.8 5.6e-27 94.5 0.0 2.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 GAN08627.1 - 1.9e-24 86.5 0.1 5.6e-24 85.0 0.1 1.9 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal FCH PF00611.23 GAN08627.1 - 1.7e-18 66.6 0.3 4.9e-18 65.2 0.3 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 GAN08627.1 - 8.5e-18 64.0 0.1 3.6e-12 46.0 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAN08627.1 - 8e-17 60.6 0.1 4.4e-10 39.0 0.0 2.8 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.22 GAN08627.1 - 8.1e-13 48.0 7.0 1.4e-12 47.3 7.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 GAN08627.1 - 2.5e-07 30.3 0.0 0.00045 19.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Golgin_A5 PF09787.9 GAN08627.1 - 0.0093 15.5 6.8 0.061 12.8 0.5 2.4 2 0 0 2 2 2 2 Golgin subfamily A member 5 HrpB7 PF09486.10 GAN08627.1 - 0.037 14.4 5.6 2.4 8.5 1.3 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF5082 PF16888.5 GAN08627.1 - 0.041 14.2 0.3 0.041 14.2 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF2318 PF10080.9 GAN08627.1 - 0.23 11.6 1.5 0.61 10.2 1.5 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_2 PF03107.16 GAN08627.1 - 0.26 11.6 4.1 0.54 10.6 4.1 1.5 1 0 0 1 1 1 0 C1 domain CotJB PF12652.7 GAN08627.1 - 0.59 10.4 3.3 0.52 10.6 0.2 2.5 3 0 0 3 3 2 0 CotJB protein PHD PF00628.29 GAN08627.1 - 1.5 8.8 7.4 2.9 7.8 7.4 1.5 1 0 0 1 1 1 0 PHD-finger RICH PF05062.12 GAN08627.1 - 2.7 8.4 9.8 0.43 11.0 0.5 3.4 3 1 1 4 4 4 0 RICH domain Seryl_tRNA_N PF02403.22 GAN08627.1 - 7.1 6.9 9.2 4.5 7.6 1.4 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MMS19_C PF12460.8 GAN08628.1 - 3.2e-87 293.4 15.9 9.9e-83 278.6 10.6 4.3 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 GAN08628.1 - 5e-77 259.0 0.1 5e-77 259.0 0.1 4.3 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 GAN08628.1 - 1.1e-07 32.1 4.3 0.0098 16.3 0.1 5.4 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 GAN08628.1 - 7.6e-06 26.3 1.4 7.1e-05 23.2 0.2 3.3 2 0 0 2 2 2 1 HEAT-like repeat ParcG PF10274.9 GAN08628.1 - 0.00026 21.1 5.5 0.0046 17.1 0.8 3.7 3 1 1 4 4 4 1 Parkin co-regulated protein ERAP1_C PF11838.8 GAN08628.1 - 0.00047 19.8 0.2 0.0043 16.6 0.1 2.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain DUF3819 PF12842.7 GAN08628.1 - 0.23 11.4 2.2 0.38 10.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) KaiA PF07688.12 GAN08628.1 - 1.4 9.0 4.7 17 5.6 0.0 2.9 3 0 0 3 3 3 0 KaiA C-terminal domain HEAT PF02985.22 GAN08628.1 - 1.7 9.1 8.1 6 7.4 0.2 5.0 5 0 0 5 5 5 0 HEAT repeat MOSC_N PF03476.16 GAN08630.1 - 1e-26 93.1 0.0 1.6e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 GAN08630.1 - 1.2e-19 70.6 0.0 2.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain FA_hydroxylase PF04116.13 GAN08631.1 - 3e-22 79.4 26.0 3e-22 79.4 26.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MoaF_C PF17409.2 GAN08631.1 - 0.79 9.4 3.8 3.4 7.4 0.0 2.8 2 1 1 3 3 3 0 MoaF C-terminal domain ECF_trnsprt PF12822.7 GAN08631.1 - 0.8 9.8 6.6 5.2 7.1 0.7 2.4 2 1 0 2 2 2 0 ECF transporter, substrate-specific component DKCLD PF08068.12 GAN08633.1 - 3.6e-35 119.8 0.3 5.1e-33 112.9 0.2 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 GAN08633.1 - 8.8e-23 80.2 0.5 1.7e-22 79.3 0.5 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 GAN08633.1 - 1.3e-22 80.8 0.2 1.3e-19 71.1 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 GAN08633.1 - 2.7e-19 68.9 0.7 5.4e-19 67.9 0.7 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 GAN08633.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain TrkH PF02386.16 GAN08634.1 - 3.3e-76 256.7 4.4 2.1e-58 198.0 0.0 3.1 2 1 1 3 3 3 3 Cation transport protein Macoilin PF09726.9 GAN08634.1 - 9.1 4.7 14.7 14 4.0 14.7 1.3 1 0 0 1 1 1 0 Macoilin family N_BRCA1_IG PF16158.5 GAN08635.1 - 1.7e-27 96.2 0.1 1e-26 93.6 0.0 2.5 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 GAN08635.1 - 9.4e-24 83.0 42.0 3.6e-08 33.1 8.2 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 GAN08635.1 - 9.8e-07 29.0 31.4 0.024 15.0 5.6 3.5 3 0 0 3 3 3 3 C1 domain PB1 PF00564.24 GAN08635.1 - 0.00049 20.0 7.3 0.0027 17.6 0.1 3.3 3 0 0 3 3 3 1 PB1 domain TSA PF03249.13 GAN08635.1 - 0.72 8.6 6.7 3.6 6.3 0.3 2.3 2 0 0 2 2 2 0 Type specific antigen Phostensin PF13914.6 GAN08635.1 - 2.3 8.9 10.2 2.9 8.5 0.2 3.5 3 0 0 3 3 3 0 Phostensin PP1-binding and SH3-binding region SUIM_assoc PF16619.5 GAN08635.1 - 7.3 6.7 33.3 0.11 12.6 6.6 4.2 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 PIP5K PF01504.18 GAN08636.1 - 2.3e-96 322.2 2.3 2.3e-96 322.2 2.3 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_hydro_3 PF00933.21 GAN08637.1 - 3.3e-88 296.1 0.1 4.6e-88 295.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 GAN08637.1 - 7.4e-16 58.4 0.0 8.2e-10 38.9 0.0 2.9 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN08637.1 - 7.9e-14 51.9 0.3 2.2e-07 31.2 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN08637.1 - 1.3e-10 41.3 0.0 7.9e-08 32.3 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAN08637.1 - 6.6e-09 35.9 0.1 0.0024 17.9 0.1 3.6 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 GAN08637.1 - 5.5e-06 26.5 0.0 1.6e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain FR47 PF08445.10 GAN08637.1 - 0.00034 20.5 0.0 1.6 8.8 0.0 3.1 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 GAN08637.1 - 0.0012 18.9 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 GAN08637.1 - 0.0064 16.6 0.0 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SCO1-SenC PF02630.14 GAN08637.1 - 0.084 12.8 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 SCO1/SenC Sec2p PF06428.11 GAN08638.1 - 4.2e-23 81.1 19.1 4.2e-23 81.1 19.1 3.0 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 GAN08638.1 - 0.0042 15.7 22.6 0.0063 15.1 22.6 1.3 1 0 0 1 1 1 1 Macoilin family DUF836 PF05768.14 GAN08638.1 - 1 9.8 8.1 2.5 8.6 7.8 1.9 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) hDGE_amylase PF14701.6 GAN08638.1 - 5.6 5.9 15.2 8 5.4 15.2 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain GAS PF13851.6 GAN08638.1 - 9.5 5.5 40.2 32 3.8 39.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Velvet PF11754.8 GAN08639.1 - 2.2e-61 208.0 0.6 3e-42 145.3 0.0 2.1 1 1 1 2 2 2 2 Velvet factor DUF4203 PF13886.6 GAN08640.1 - 2.3e-35 122.1 36.9 2.3e-35 122.1 36.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) SSP160 PF06933.11 GAN08640.1 - 0.0082 14.4 2.3 0.012 13.9 2.3 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Zn_clus PF00172.18 GAN08641.1 - 0.00045 20.3 11.3 0.00045 20.3 11.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAN08641.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold DASH_Duo1 PF08651.10 GAN08641.1 - 0.32 10.8 2.9 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 ANAPC3 PF12895.7 GAN08642.1 - 4.6e-22 78.0 9.8 2.2e-14 53.4 0.3 3.8 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAN08642.1 - 3.8e-17 61.0 6.8 0.00032 20.6 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAN08642.1 - 7e-17 60.5 0.6 0.0019 17.9 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN08642.1 - 3.5e-16 58.0 6.5 0.0031 17.6 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAN08642.1 - 9.7e-12 45.0 5.6 0.00029 21.1 0.2 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN08642.1 - 1.6e-10 41.3 4.6 0.052 14.1 0.0 6.2 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAN08642.1 - 2.1e-08 33.6 1.2 0.61 10.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN08642.1 - 2.7e-08 34.0 0.3 0.18 12.7 0.2 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN08642.1 - 1e-07 32.4 0.7 0.0056 17.3 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAN08642.1 - 4e-06 26.5 2.9 0.54 10.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN08642.1 - 1.2e-05 24.9 1.1 0.97 9.2 0.0 4.6 4 0 0 4 4 4 2 TPR repeat TPR_3 PF07720.12 GAN08642.1 - 1.2e-05 25.1 1.6 0.015 15.3 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN08642.1 - 0.0002 21.8 4.8 0.15 12.7 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN08642.1 - 0.00091 19.4 6.0 12 6.6 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAN08642.1 - 0.0027 17.0 1.1 2.2 7.4 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAN08642.1 - 0.068 13.8 0.9 7.3 7.5 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAN08642.1 - 0.071 13.2 0.5 18 5.5 0.0 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat EamA PF00892.20 GAN08643.1 - 1.3e-05 25.4 36.4 0.00038 20.6 4.5 2.7 3 0 0 3 3 3 2 EamA-like transporter family SF3b10 PF07189.11 GAN08643.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) CENP-N PF05238.13 GAN08643.1 - 0.076 12.3 1.2 0.11 11.8 1.2 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4260 PF14079.6 GAN08643.1 - 2.4 8.1 11.2 0.15 12.0 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) MFS_1 PF07690.16 GAN08644.1 - 6.8e-24 84.4 58.9 3.4e-23 82.1 50.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAN08644.1 - 3.6e-08 32.3 31.2 5.6e-08 31.7 31.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_S8 PF00410.19 GAN08645.1 - 4.6e-24 84.8 0.0 5.3e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Pescadillo_N PF06732.11 GAN08646.1 - 4.5e-124 413.4 4.1 4.5e-124 413.4 4.1 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 GAN08646.1 - 7.1e-11 42.4 0.3 3.7e-10 40.1 0.0 2.3 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAN08646.1 - 1.5e-06 28.5 0.0 1.5e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Sigma70_ner PF04546.13 GAN08646.1 - 0.8 9.5 14.0 0.83 9.5 4.7 3.0 3 0 0 3 3 3 0 Sigma-70, non-essential region Podoplanin PF05808.11 GAN08646.1 - 2.9 8.0 4.5 32 4.6 0.8 2.3 2 0 0 2 2 2 0 Podoplanin zf-C2H2 PF00096.26 GAN08647.1 - 2.2e-12 46.7 9.4 5e-06 26.7 1.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN08647.1 - 7.3e-06 26.4 15.2 0.001 19.7 1.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN08647.1 - 1.5e-05 25.2 15.2 4.5e-05 23.7 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 GAN08647.1 - 0.0021 17.8 7.4 0.58 10.0 1.3 3.2 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 GAN08647.1 - 0.0057 16.6 2.0 0.72 9.9 0.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GAN08647.1 - 0.0084 15.9 2.0 0.4 10.5 0.1 2.7 2 0 0 2 2 2 1 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 GAN08647.1 - 0.1 12.7 0.9 3 8.0 0.5 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 GAN08647.1 - 0.28 11.5 3.8 0.82 10.0 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 GAN08647.1 - 2.4 8.2 7.6 5.3 7.1 1.1 2.6 2 0 0 2 2 2 0 BED zinc finger Actin PF00022.19 GAN08648.1 - 2.1e-131 438.3 0.0 6e-131 436.8 0.0 1.7 1 1 0 1 1 1 1 Actin Mid1 PF12929.7 GAN08648.1 - 2.4e-89 300.5 13.4 6.6e-89 299.0 13.4 1.7 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Glyco_tran_28_C PF04101.16 GAN08648.1 - 3.8e-16 59.5 2.0 1e-10 41.9 0.0 2.6 3 0 0 3 3 3 2 Glycosyltransferase family 28 C-terminal domain Fz PF01392.22 GAN08648.1 - 4.8e-05 23.9 5.0 0.0062 17.1 1.5 2.8 2 0 0 2 2 2 2 Fz domain Cullin PF00888.22 GAN08649.1 - 1.7e-181 605.0 21.0 2.3e-146 489.0 14.1 2.2 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 GAN08649.1 - 6.3e-28 96.6 2.6 3.2e-27 94.4 2.6 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain RRM_1 PF00076.22 GAN08650.1 - 4e-31 106.7 0.4 4.7e-16 58.4 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 GAN08650.1 - 0.0074 16.1 0.2 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain OB_RNB PF08206.11 GAN08650.1 - 0.0092 15.6 0.1 3.7 7.3 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease B OB domain UPF0180 PF03698.13 GAN08650.1 - 0.0099 16.0 1.5 0.15 12.3 0.0 3.2 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0180) Sugar_tr PF00083.24 GAN08651.1 - 1.9e-95 320.4 15.5 2.5e-95 320.0 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN08651.1 - 2.1e-34 119.0 18.6 5.3e-21 74.9 1.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN08651.1 - 2.1e-05 23.2 4.3 2.1e-05 23.2 4.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAN08651.1 - 0.00063 18.2 10.3 0.0021 16.5 0.6 3.2 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 GAN08651.1 - 0.21 10.9 18.9 0.16 11.2 5.7 2.6 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB ORF11CD3 PF10549.9 GAN08652.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 ORF11CD3 domain Sec7 PF01369.20 GAN08653.1 - 1.1e-28 100.1 0.7 1.9e-28 99.4 0.7 1.4 1 0 0 1 1 1 1 Sec7 domain DUF4456 PF14644.6 GAN08653.1 - 0.25 11.0 10.5 1.3 8.7 10.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) LAG1-DNAbind PF09271.11 GAN08654.1 - 8.9e-23 81.6 8.8 4e-13 50.2 0.3 2.6 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.10 GAN08654.1 - 2.4e-22 79.8 0.1 5.5e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain TSA PF03249.13 GAN08654.1 - 0.38 9.5 4.9 0.55 9.0 4.9 1.2 1 0 0 1 1 1 0 Type specific antigen SUIM_assoc PF16619.5 GAN08654.1 - 3.3 7.9 21.7 0.065 13.3 7.4 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FANCI_S2 PF14676.6 GAN08655.1 - 0.028 14.7 0.1 0.068 13.5 0.1 1.6 1 0 0 1 1 1 0 FANCI solenoid 2 IFT57 PF10498.9 GAN08655.1 - 1.6 7.6 16.8 0.93 8.4 8.6 2.9 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 GAN08655.1 - 1.8 8.0 7.3 4.1 6.9 7.0 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit A2M PF00207.22 GAN08656.1 - 0.087 12.7 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin family GPI-anchored PF10342.9 GAN08657.1 - 8.4e-06 26.5 1.7 8.4e-06 26.5 1.7 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAT1 PF09770.9 GAN08658.1 - 1.2e-141 473.8 38.7 1e-128 431.0 20.7 2.0 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 YqzH PF14164.6 GAN08658.1 - 0.0073 16.4 0.1 0.052 13.6 0.0 2.6 2 0 0 2 2 2 1 YqzH-like protein PQ-loop PF04193.14 GAN08659.1 - 3.4e-38 129.2 16.1 4e-21 74.5 0.7 3.1 4 0 0 4 4 4 2 PQ loop repeat DUF3169 PF11368.8 GAN08659.1 - 0.00066 19.3 4.2 0.013 15.0 4.1 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3169) COX6A PF02046.15 GAN08659.1 - 0.0077 16.7 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa FA_desaturase PF00487.24 GAN08659.1 - 0.012 15.5 0.6 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase LRR19-TM PF15176.6 GAN08659.1 - 0.047 13.7 0.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Bac_export_2 PF01312.19 GAN08659.1 - 0.078 12.2 1.1 0.17 11.1 1.1 1.5 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family MtN3_slv PF03083.16 GAN08659.1 - 0.14 12.2 0.3 0.14 12.2 0.3 3.8 3 2 2 5 5 5 0 Sugar efflux transporter for intercellular exchange Mt_ATP-synt_D PF05873.12 GAN08660.1 - 9.6e-21 74.2 3.2 1.1e-20 74.0 3.2 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) 120_Rick_ant PF12574.8 GAN08660.1 - 0.00034 19.9 2.1 0.00042 19.6 1.6 1.4 1 1 0 1 1 1 1 120 KDa Rickettsia surface antigen RPW8 PF05659.11 GAN08660.1 - 0.0014 18.3 1.3 0.0098 15.6 0.4 2.4 2 1 1 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prominin PF05478.11 GAN08660.1 - 0.0053 14.8 3.3 0.0063 14.5 3.3 1.0 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.12 GAN08660.1 - 0.019 15.0 1.6 0.027 14.5 1.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5446 PF17522.2 GAN08660.1 - 0.022 14.9 4.1 0.03 14.5 0.1 2.4 3 0 0 3 3 2 0 Family of unknown function (DUF5446) Vps51 PF08700.11 GAN08660.1 - 0.023 14.7 1.9 6.8 6.8 1.9 2.4 1 1 0 1 1 1 0 Vps51/Vps67 Pet20 PF08692.10 GAN08660.1 - 0.025 15.3 0.2 0.043 14.5 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial protein Pet20 DUF1870 PF08965.10 GAN08660.1 - 0.029 14.4 0.5 0.14 12.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) BST2 PF16716.5 GAN08660.1 - 0.029 15.0 3.2 0.1 13.2 1.0 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CdvA PF18822.1 GAN08660.1 - 0.029 14.2 2.1 0.43 10.4 0.6 2.3 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF4407 PF14362.6 GAN08660.1 - 0.031 13.6 0.9 0.04 13.3 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 GAN08660.1 - 0.052 12.8 3.2 0.064 12.5 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein BLOC1_2 PF10046.9 GAN08660.1 - 0.054 13.8 4.1 0.13 12.6 1.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 GAN08660.1 - 0.09 12.8 4.0 0.17 12.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4600 PF15372.6 GAN08660.1 - 0.13 12.7 4.1 5 7.6 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Cob_adeno_trans PF01923.18 GAN08660.1 - 0.14 12.3 1.7 0.26 11.4 0.3 1.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase STAT_alpha PF01017.20 GAN08660.1 - 0.15 11.9 3.8 0.21 11.4 3.8 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Glutaredoxin2_C PF04399.13 GAN08660.1 - 0.16 11.8 1.9 0.31 10.9 0.2 2.1 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Rx_N PF18052.1 GAN08660.1 - 0.22 11.8 2.9 0.72 10.2 0.3 2.4 1 1 0 2 2 2 0 Rx N-terminal domain TPR_MLP1_2 PF07926.12 GAN08660.1 - 0.36 10.9 8.6 1.4 9.0 2.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF148 PF02520.17 GAN08660.1 - 0.36 10.9 7.5 0.39 10.8 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 Med9 PF07544.13 GAN08660.1 - 0.49 10.5 4.1 34 4.6 0.6 3.1 1 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 GAN08660.1 - 0.68 10.2 5.2 7.7 6.9 3.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc24 PF08286.11 GAN08660.1 - 1.1 9.5 5.3 2 8.7 0.7 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2408 PF10303.9 GAN08660.1 - 1.4 9.4 4.9 2.6 8.6 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Spectrin PF00435.21 GAN08660.1 - 1.6 9.3 5.9 3.8 8.1 4.6 2.0 1 1 1 2 2 2 0 Spectrin repeat NPV_P10 PF05531.12 GAN08660.1 - 1.8 9.1 9.5 1.3 9.5 2.3 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 GAN08660.1 - 4.9 7.8 9.6 7.1 7.3 2.6 2.5 1 1 2 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SR-25 PF10500.9 GAN08663.1 - 0.15 11.7 10.4 0.34 10.5 10.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.19 GAN08664.1 - 5.6e-73 246.2 0.0 7.9e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAN08664.1 - 0.00031 20.8 0.0 0.00082 19.4 0.0 1.8 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 GAN08664.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 GAN08664.1 - 0.0055 16.0 0.7 0.23 10.7 0.2 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN08664.1 - 0.0079 16.4 0.1 0.033 14.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAN08664.1 - 0.012 14.8 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 GAN08664.1 - 0.037 14.5 0.3 0.16 12.4 0.1 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 GAN08664.1 - 0.04 13.2 0.0 0.089 12.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAN08664.1 - 0.047 12.4 0.1 0.088 11.5 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 GAN08664.1 - 0.065 12.6 1.0 0.16 11.3 1.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAN08664.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 GAN08664.1 - 1.1 8.8 3.5 4.4 6.8 1.4 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase B12D PF06522.11 GAN08665.1 - 4.5e-19 68.0 0.0 5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF5423 PF17461.2 GAN08665.1 - 0.0029 16.5 0.0 0.0036 16.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5423) COX7a PF02238.15 GAN08665.1 - 0.042 14.3 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII DUF3945 PF13101.6 GAN08665.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) CTP_transf_like PF01467.26 GAN08666.1 - 8.9e-30 103.8 0.0 1.9e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 GAN08666.1 - 0.027 14.6 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5639) HLH PF00010.26 GAN08667.1 - 4.3e-16 58.6 0.9 8.4e-16 57.7 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAP1 PF08601.10 GAN08667.1 - 0.0023 17.7 3.7 0.0029 17.4 3.7 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 GPCR_chapero_1 PF11904.8 GAN08667.1 - 0.0062 16.0 0.4 0.0069 15.9 0.4 1.1 1 0 0 1 1 1 1 GPCR-chaperone DUF5638 PF18688.1 GAN08668.1 - 0.0031 17.8 0.1 0.013 15.8 0.1 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5638) DUF900 PF05990.12 GAN08668.1 - 0.045 13.3 0.1 0.084 12.4 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF4477 PF14780.6 GAN08669.1 - 1.5e-20 73.7 3.8 2.5e-20 72.9 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) UPF0020 PF01170.18 GAN08670.1 - 4.7e-10 39.5 0.0 3.1e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 GAN08670.1 - 0.00061 19.6 0.0 0.26 11.0 0.0 2.9 2 2 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 GAN08670.1 - 0.00063 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Svf1_C PF17187.4 GAN08671.1 - 5.6e-51 172.6 1.8 8.5e-51 172.1 1.8 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 GAN08671.1 - 8.1e-34 117.0 0.6 1.8e-33 115.9 0.6 1.6 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Peptidase_M13_N PF05649.13 GAN08672.1 - 7.2e-104 348.5 0.0 1e-103 348.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAN08672.1 - 2.5e-69 233.0 0.1 3.7e-69 232.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 HLH PF00010.26 GAN08673.1 - 1.9e-15 56.6 1.3 4.9e-15 55.2 1.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L50 PF10501.9 GAN08675.1 - 5.8e-11 42.5 1.4 9.9e-11 41.8 1.4 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S WD40 PF00400.32 GAN08676.1 - 1.3e-45 152.4 12.5 1e-05 26.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08676.1 - 4.6e-15 55.7 1.2 0.0036 17.6 0.0 6.2 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAN08676.1 - 0.00012 20.7 0.3 0.00059 18.5 0.2 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.6 GAN08676.1 - 0.00029 20.3 0.7 0.00083 18.8 0.6 2.0 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 GAN08676.1 - 0.0003 19.9 1.3 0.054 12.4 0.0 3.8 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAN08676.1 - 0.0052 15.5 6.8 0.14 10.7 0.0 4.1 2 1 3 5 5 5 2 Nucleoporin Nup120/160 PH PF00169.29 GAN08677.1 - 1.9e-05 25.1 1.6 4.7e-05 23.8 1.6 1.6 1 0 0 1 1 1 1 PH domain DUF2387 PF09526.10 GAN08677.1 - 0.047 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Pkinase PF00069.25 GAN08678.1 - 5.8e-48 163.6 0.0 1.2e-47 162.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08678.1 - 6.5e-30 104.3 0.0 1.2e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN08678.1 - 0.00022 20.6 0.0 0.00053 19.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN08678.1 - 0.00092 18.3 1.8 0.0025 16.8 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 GAN08678.1 - 0.073 12.7 0.2 0.17 11.5 0.2 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Hist_deacetyl PF00850.19 GAN08679.1 - 1.1e-81 274.7 0.1 2.9e-81 273.3 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Ndc1_Nup PF09531.10 GAN08680.1 - 1.7 7.2 6.3 1.7 7.2 6.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 GAN08680.1 - 2.3 7.0 14.7 3.2 6.5 14.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GAS PF13851.6 GAN08681.1 - 0.00058 19.3 4.3 0.0013 18.2 4.3 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TBCC_N PF16752.5 GAN08681.1 - 0.0015 19.0 2.4 0.0051 17.2 2.4 1.9 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Atg14 PF10186.9 GAN08681.1 - 0.0023 17.1 3.6 0.0033 16.6 2.6 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Cluap1 PF10234.9 GAN08681.1 - 0.0026 17.2 4.0 0.026 13.9 1.9 2.4 2 0 0 2 2 2 1 Clusterin-associated protein-1 ATG16 PF08614.11 GAN08681.1 - 0.0032 17.7 4.0 0.0032 17.7 4.0 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAN08681.1 - 0.0067 15.4 2.5 0.0067 15.4 2.5 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein DivIC PF04977.15 GAN08681.1 - 0.016 15.0 4.7 0.023 14.4 3.3 1.9 1 1 1 2 2 2 0 Septum formation initiator KxDL PF10241.9 GAN08681.1 - 0.018 15.3 2.0 0.018 15.3 2.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein Lebercilin PF15619.6 GAN08681.1 - 0.018 14.7 2.6 0.018 14.7 2.6 1.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Rogdi_lz PF10259.9 GAN08681.1 - 0.019 14.5 1.8 0.043 13.3 1.3 1.7 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein Rootletin PF15035.6 GAN08681.1 - 0.019 15.0 2.8 0.019 15.0 2.8 2.4 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 GAN08681.1 - 0.023 15.1 2.1 0.023 15.1 2.1 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 GAN08681.1 - 0.026 14.5 4.4 0.026 14.5 4.4 2.0 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Tup_N PF08581.10 GAN08681.1 - 0.026 14.8 2.4 0.026 14.8 2.4 2.5 2 1 1 3 3 2 0 Tup N-terminal MtrB PF05440.12 GAN08681.1 - 0.026 14.9 0.1 0.056 13.9 0.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF848 PF05852.11 GAN08681.1 - 0.029 14.5 2.0 0.029 14.5 2.0 1.8 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) KinB_sensor PF16767.5 GAN08681.1 - 0.031 14.7 0.2 0.088 13.3 0.2 1.8 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB ZapB PF06005.12 GAN08681.1 - 0.039 14.4 6.1 0.43 11.1 5.4 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Foie-gras_1 PF11817.8 GAN08681.1 - 0.041 13.5 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 HMMR_N PF15905.5 GAN08681.1 - 0.073 12.5 6.4 0.1 12.1 6.0 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HALZ PF02183.18 GAN08681.1 - 0.094 13.0 1.5 0.12 12.6 0.3 1.9 2 0 0 2 2 1 0 Homeobox associated leucine zipper HalX PF08663.10 GAN08681.1 - 0.1 12.9 2.7 0.36 11.2 2.7 2.0 1 1 0 1 1 1 0 HalX domain ParB PF08775.10 GAN08681.1 - 0.17 12.4 6.3 0.048 14.1 1.7 2.5 2 2 1 3 3 1 0 ParB family KLRAQ PF10205.9 GAN08681.1 - 0.22 11.8 6.3 0.059 13.6 1.2 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein SlyX PF04102.12 GAN08681.1 - 0.24 12.1 2.4 0.74 10.5 0.8 2.6 1 1 1 2 2 2 0 SlyX APG6_N PF17675.1 GAN08681.1 - 0.25 11.9 6.9 0.12 13.0 3.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 GAN08681.1 - 0.27 11.5 3.7 0.29 11.4 0.7 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 GAN08681.1 - 0.3 10.3 4.5 0.15 11.3 1.3 1.9 2 0 0 2 2 2 0 TMPIT-like protein Occludin_ELL PF07303.13 GAN08681.1 - 0.31 11.8 4.1 0.15 12.8 1.4 1.9 2 0 0 2 2 1 0 Occludin homology domain Prominin PF05478.11 GAN08681.1 - 0.39 8.6 3.8 0.12 10.3 0.7 1.6 2 0 0 2 2 2 0 Prominin YabA PF06156.13 GAN08681.1 - 0.5 11.0 8.7 0.71 10.5 0.5 3.0 2 2 1 3 3 3 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 GAN08681.1 - 0.6 9.6 6.2 0.16 11.6 2.4 1.9 2 1 1 3 3 2 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 GAN08681.1 - 0.64 10.1 4.6 0.23 11.5 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 GAN08681.1 - 0.66 9.8 7.6 0.056 13.3 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Ead_Ea22 PF13935.6 GAN08681.1 - 0.71 10.5 10.0 3.9 8.1 1.2 2.8 3 0 0 3 3 3 0 Ead/Ea22-like protein FlaC_arch PF05377.11 GAN08681.1 - 1 9.8 5.5 3.5 8.1 1.9 2.9 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 GAN08681.1 - 1.2 9.2 8.0 0.21 11.7 3.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3972 PF13118.6 GAN08681.1 - 1.2 9.6 9.9 0.63 10.5 3.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3972) zf-C4H2 PF10146.9 GAN08681.1 - 3.5 7.9 11.8 0.097 13.0 3.9 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein YojJ PF10372.9 GAN08681.1 - 8.9 6.5 7.1 7.2 6.8 0.6 3.1 4 0 0 4 4 3 0 Bacterial membrane-spanning protein N-terminus zf-C2H2 PF00096.26 GAN08682.1 - 4.6e-09 36.2 27.7 0.00066 20.0 5.5 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAN08682.1 - 0.00093 19.8 0.4 0.00093 19.8 0.4 4.0 2 1 2 4 4 4 1 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 GAN08682.1 - 0.0012 19.2 5.6 0.0012 19.2 5.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 GAN08682.1 - 0.0028 18.0 7.7 0.028 14.8 1.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN08682.1 - 0.025 14.9 1.8 0.025 14.9 1.8 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAN08682.1 - 0.026 15.4 3.7 0.026 15.4 3.7 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf_ZIC PF18366.1 GAN08682.1 - 0.4 10.8 0.0 0.4 10.8 0.0 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 GAN08682.1 - 0.58 10.3 4.5 1.6 8.9 4.5 1.7 1 0 0 1 1 1 0 Aberrant zinc-finger MFS_1 PF07690.16 GAN08683.1 - 4.2e-57 193.7 46.6 1.5e-54 185.3 48.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN08683.1 - 1.4e-16 60.1 18.4 1.4e-16 60.1 18.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAN08683.1 - 1.9e-14 53.4 7.1 1.9e-14 53.4 7.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAN08683.1 - 5e-05 22.3 27.1 0.00037 19.5 8.6 2.2 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 GAN08683.1 - 4.5 5.4 20.6 0.12 10.6 3.2 3.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 GAN08684.1 - 3.1e-101 339.0 0.0 3.7e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN08684.1 - 1.2e-13 51.9 0.1 7e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain V-ATPase_C PF03223.15 GAN08685.1 - 0.033 13.6 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 V-ATPase subunit C DUF3391 PF11871.8 GAN08685.1 - 6.4 7.3 5.6 1.7 9.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) S10_plectin PF03501.15 GAN08686.1 - 9.7e-43 144.2 0.0 1.2e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Kinase-like PF14531.6 GAN08686.1 - 0.0066 15.8 0.0 0.0072 15.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF1495 PF07381.11 GAN08686.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF4364 PF14277.6 GAN08686.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) zf_CCCH_4 PF18345.1 GAN08687.1 - 1.6e-13 50.2 54.1 2.9e-05 24.0 6.4 6.3 5 2 0 5 5 5 4 Zinc finger domain zf-CCCH PF00642.24 GAN08687.1 - 3.2e-12 46.0 48.4 9.4e-06 25.4 1.5 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 GAN08687.1 - 4.2e-08 33.4 24.1 0.17 12.1 0.2 4.8 3 1 0 3 3 3 3 Zinc-finger containing family zf-CCCH_4 PF18044.1 GAN08687.1 - 1.9e-05 24.3 56.2 2.4e-05 24.0 3.2 6.1 6 1 0 6 6 6 4 CCCH-type zinc finger Torus PF16131.5 GAN08687.1 - 0.00013 22.6 6.6 0.00052 20.7 0.9 6.1 3 1 3 6 6 6 4 Torus domain DUF4680 PF15730.5 GAN08688.1 - 0.069 13.5 1.2 0.079 13.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Herpes_capsid PF06112.11 GAN08688.1 - 4.3 7.4 12.0 5.2 7.1 12.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein IFRD PF05004.13 GAN08689.1 - 2.9e-52 177.7 2.8 2.9e-52 177.7 2.8 1.9 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Acp26Ab PF05777.12 GAN08689.1 - 0.032 14.9 0.2 3.3 8.4 0.0 3.2 3 0 0 3 3 3 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) DUF1053 PF06327.14 GAN08689.1 - 0.055 14.0 2.1 11 6.7 0.1 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) SPO22 PF08631.10 GAN08689.1 - 0.073 12.6 1.3 0.59 9.6 0.3 2.4 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like Xan_ur_permease PF00860.20 GAN08690.1 - 9.4e-58 195.8 27.8 1.3e-56 192.0 27.8 2.0 1 1 0 1 1 1 1 Permease family MPC PF03650.13 GAN08690.1 - 0.021 15.0 0.4 0.084 13.0 0.0 2.0 2 1 1 3 3 3 0 Mitochondrial pyruvate carriers Asp PF00026.23 GAN08693.1 - 1.9e-52 178.6 1.9 5.8e-52 177.1 1.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN08693.1 - 1.8e-09 38.1 5.3 5.1e-08 33.3 3.5 2.6 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Glyco_hydro_18 PF00704.28 GAN08694.1 - 7.4e-88 295.3 2.6 8.6e-88 295.0 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ATP_sub_h PF10775.9 GAN08695.1 - 1.4e-23 82.6 1.5 1.8e-23 82.3 1.5 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 GAN08695.1 - 0.061 13.7 0.1 0.072 13.5 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Oxidored_FMN PF00724.20 GAN08696.1 - 9.8e-76 255.2 0.0 1.2e-75 255.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 GAN08696.1 - 0.0029 16.8 0.6 0.011 14.9 0.0 2.0 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) ArfGap PF01412.18 GAN08697.1 - 8.8e-42 141.9 3.9 1.9e-41 140.8 3.9 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf WAC_Acf1_DNA_bd PF10537.9 GAN08701.1 - 3.4e-32 111.0 3.2 3.4e-32 111.0 3.2 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 GAN08701.1 - 5.8e-24 84.4 0.2 5.8e-24 84.4 0.2 4.0 5 1 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 GAN08701.1 - 7.1e-11 42.3 0.3 1.5e-10 41.2 0.3 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 GAN08701.1 - 0.00023 20.6 0.0 0.00047 19.6 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 TBCA PF02970.16 GAN08702.1 - 7.6e-28 96.7 6.8 9.6e-28 96.4 6.8 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.11 GAN08702.1 - 0.027 13.4 6.8 0.029 13.3 5.5 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Zw10 PF06248.13 GAN08702.1 - 0.051 12.1 2.8 0.054 12.1 2.8 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Val_tRNA-synt_C PF10458.9 GAN08702.1 - 0.15 12.4 4.1 5.9 7.3 0.2 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Glyco_hydro_85 PF03644.13 GAN08703.1 - 2e-96 323.0 1.5 2.9e-96 322.4 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 WLM PF08325.10 GAN08704.1 - 3.9e-46 157.5 0.1 7.3e-46 156.7 0.0 1.4 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 GAN08704.1 - 1.4e-14 53.6 0.9 1.3e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAN08704.1 - 0.058 13.9 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GAN08704.1 - 0.11 12.6 1.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain DUF3752 PF12572.8 GAN08704.1 - 0.11 13.0 1.8 0.68 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DUF45 PF01863.17 GAN08704.1 - 0.29 11.2 1.6 0.42 10.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 LSM PF01423.22 GAN08705.1 - 2.3e-18 65.6 1.3 3e-18 65.3 1.3 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 GAN08705.1 - 0.03 14.4 0.2 0.046 13.9 0.2 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain UBX PF00789.20 GAN08706.1 - 3e-15 56.2 0.0 8.6e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 GAN08706.1 - 1.3e-06 28.1 1.0 2.6e-06 27.1 1.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 GAN08706.1 - 0.00015 21.9 0.0 0.00059 20.0 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like V_ATPase_I PF01496.19 GAN08706.1 - 0.00067 17.7 1.8 0.00067 17.7 1.8 1.9 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Peptidase_M24_C PF16188.5 GAN08706.1 - 0.1 12.7 0.5 0.74 9.9 0.1 2.4 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 NPAT_C PF15712.5 GAN08706.1 - 0.14 10.8 0.8 0.24 10.0 0.8 1.3 1 0 0 1 1 1 0 NPAT C terminus DUF4862 PF16154.5 GAN08706.1 - 0.17 11.2 2.2 0.25 10.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4862) DUF2347 PF09804.9 GAN08706.1 - 0.52 9.9 4.0 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) CREPT PF16566.5 GAN08706.1 - 1 9.5 12.3 0.071 13.3 6.8 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour AAA_23 PF13476.6 GAN08706.1 - 1.8 9.0 15.3 0.067 13.7 4.9 2.4 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.16 GAN08706.1 - 3.1 6.6 4.4 10 4.9 0.3 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein F-box-like PF12937.7 GAN08707.1 - 2.8e-05 23.9 0.1 9.7e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAN08707.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 GAN08707.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box DHHA2 PF02833.14 GAN08708.1 - 1.9e-27 96.2 0.6 2.9e-27 95.6 0.6 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 GAN08708.1 - 1.3e-09 38.1 0.2 3.1e-09 37.0 0.2 1.6 1 0 0 1 1 1 1 DHH family Ribosomal_S15 PF00312.22 GAN08709.1 - 3.9e-30 103.9 1.9 3.9e-30 103.9 1.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S15 DnaI_N PF07319.11 GAN08709.1 - 0.45 11.2 4.5 2.4 8.9 0.0 2.8 3 1 0 3 3 3 0 Primosomal protein DnaI N-terminus Arginase PF00491.21 GAN08710.1 - 1.2e-75 254.6 0.0 1.4e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aldedh PF00171.22 GAN08711.1 - 6.2e-91 305.2 0.0 6.9e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IQCJ-SCHIP1 PF15157.6 GAN08712.1 - 8.8 6.2 13.0 1.8 8.4 4.9 2.2 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Pyr_redox_2 PF07992.14 GAN08713.1 - 1.1e-68 231.7 7.6 1.1e-68 231.7 7.6 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAN08713.1 - 1.9e-41 140.7 0.2 6.9e-41 139.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAN08713.1 - 9.1e-21 74.2 7.1 1.3e-17 64.1 1.4 3.8 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN08713.1 - 2.7e-13 50.1 4.7 2.3e-11 43.7 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAN08713.1 - 1.2e-10 41.2 6.8 9e-08 31.7 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAN08713.1 - 1.4e-09 37.6 9.7 2.1e-09 37.0 1.9 2.6 2 2 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 GAN08713.1 - 1.6e-08 34.1 1.2 3.4e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 GAN08713.1 - 1.6e-08 34.6 2.8 4.4e-05 23.6 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAN08713.1 - 1.8e-08 33.9 14.0 5.2e-08 32.4 1.2 3.9 2 1 1 4 4 4 2 FAD binding domain HI0933_like PF03486.14 GAN08713.1 - 2.6e-06 26.4 12.2 1.7e-05 23.7 0.7 3.9 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 GAN08713.1 - 6.1e-06 25.7 9.8 0.0064 15.8 0.5 3.2 2 1 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 GAN08713.1 - 6.3e-06 25.6 4.8 0.0036 16.6 0.8 3.1 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 GAN08713.1 - 0.00064 19.0 0.5 0.59 9.2 0.1 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 GAN08713.1 - 0.012 15.5 6.3 0.036 14.0 0.8 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAN08713.1 - 0.016 14.8 3.5 0.16 11.5 0.3 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 GAN08713.1 - 0.023 14.3 16.2 0.024 14.2 0.2 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase XdhC_C PF13478.6 GAN08713.1 - 0.08 13.5 0.1 5.3 7.6 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 GAN08713.1 - 0.14 12.6 2.7 6.2 7.3 0.3 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAN08713.1 - 0.54 9.2 8.2 0.12 11.4 0.4 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein HAD_2 PF13419.6 GAN08714.1 - 1.6e-07 31.6 0.0 2.6e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN08714.1 - 4.9e-07 30.2 0.0 9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN08714.1 - 7.3e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 GAN08714.1 - 0.053 13.4 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase ASPRs PF17641.2 GAN08715.1 - 0.042 14.1 0.6 0.056 13.7 0.6 1.2 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related Arrestin_N PF00339.29 GAN08716.1 - 1.3e-16 61.0 0.0 2.7e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN08716.1 - 3.1e-06 27.7 0.0 7.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 GAN08716.1 - 0.00033 19.9 1.1 0.00067 18.9 0.1 1.8 2 0 0 2 2 2 1 Rgp1 LDB19 PF13002.7 GAN08716.1 - 0.00085 19.1 0.1 0.0043 16.8 0.0 2.1 2 1 0 2 2 2 1 Arrestin_N terminal like Ku_N PF03731.15 GAN08717.1 - 1.1e-30 107.1 0.3 1.6e-30 106.5 0.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 GAN08717.1 - 3.6e-26 92.2 0.0 8.3e-22 77.9 0.0 2.3 1 1 1 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 GAN08717.1 - 0.00051 20.7 0.6 0.0025 18.5 0.2 2.5 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 GAN08717.1 - 0.035 14.4 0.1 0.19 12.0 0.2 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain DUF515 PF04415.12 GAN08718.1 - 0.42 8.9 3.4 0.41 9.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PhrC_PhrF PF11131.8 GAN08718.1 - 0.9 9.2 5.2 1.3 8.6 5.2 1.2 1 0 0 1 1 1 0 Rap-phr extracellular signalling Pectate_lyase_3 PF12708.7 GAN08719.1 - 0.0035 17.2 8.9 0.24 11.2 7.3 3.4 1 1 1 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 GAN08719.1 - 0.027 14.3 19.5 0.04 13.8 2.9 2.9 2 2 0 2 2 2 0 Right handed beta helix region Aa_trans PF01490.18 GAN08720.1 - 6.1e-65 219.5 24.5 7.3e-65 219.3 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cytochrom_B_C PF00032.17 GAN08720.1 - 3.1 8.1 9.8 0.63 10.4 0.6 3.4 3 1 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD SBF_like PF13593.6 GAN08721.1 - 6.8e-83 278.6 15.0 8e-83 278.3 15.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 GAN08721.1 - 4.7e-08 32.9 7.8 4.7e-08 32.9 7.8 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family DEAD PF00270.29 GAN08722.1 - 4.3e-47 160.1 0.0 1.1e-46 158.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN08722.1 - 2.6e-28 98.6 0.1 9.6e-28 96.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain tRNA-synt_2d PF01409.20 GAN08723.1 - 1.8e-49 168.4 0.8 2.3e-28 99.3 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GAN08723.1 - 1.4e-20 73.5 0.0 4.6e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PHD PF00628.29 GAN08723.1 - 9.9e-07 28.6 11.7 9.9e-07 28.6 11.7 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 GAN08723.1 - 5.2e-05 22.7 2.7 0.00014 21.3 2.7 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 GAN08723.1 - 1.2 9.6 10.7 3 8.3 10.7 1.7 1 0 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.16 GAN08723.1 - 1.7 8.9 12.5 0.85 9.8 7.9 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C2H2_jaz PF12171.8 GAN08723.1 - 4.2 7.8 10.9 2.1 8.8 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PHD_4 PF16866.5 GAN08723.1 - 5.1 7.3 11.4 24 5.1 11.4 2.3 1 1 0 1 1 1 0 PHD-finger Glucosamine_iso PF01182.20 GAN08724.1 - 3.6e-21 76.1 0.0 5.4e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 GAN08725.1 - 2.5e-62 210.4 0.0 3.4e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN08725.1 - 1.8e-59 201.0 0.0 3e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase ERCC4 PF02732.15 GAN08726.1 - 0.067 13.4 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 ERCC4 domain Exo_endo_phos PF03372.23 GAN08727.1 - 2.2e-19 69.9 0.0 3e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF810 PF05664.11 GAN08727.1 - 0.086 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) NCA2 PF08637.10 GAN08728.1 - 1.7e-86 290.0 2.2 2.9e-86 289.2 2.2 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 PGM_PMM_I PF02878.16 GAN08729.1 - 4e-17 62.2 0.2 1.4e-08 34.5 0.0 3.4 2 2 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 GAN08729.1 - 7e-13 48.6 0.3 2e-12 47.1 0.3 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 GAN08729.1 - 4.1e-05 24.1 0.6 0.00053 20.6 0.2 3.1 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAN08729.1 - 0.018 15.2 0.3 0.069 13.3 0.3 2.1 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Ribosomal_L7Ae PF01248.26 GAN08730.1 - 1.7e-26 91.8 0.2 2.5e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 GAN08730.1 - 0.00034 20.7 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 BAR PF03114.18 GAN08731.1 - 7.8e-45 153.4 2.6 9.4e-45 153.1 2.6 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAN08731.1 - 6.6e-08 32.5 1.3 9.5e-08 32.0 1.3 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 GAN08731.1 - 0.0003 20.4 4.1 0.00079 19.1 4.1 1.7 1 1 0 1 1 1 1 Arfaptin-like domain AAA_13 PF13166.6 GAN08731.1 - 0.0061 15.3 6.0 0.0078 14.9 6.0 1.1 1 0 0 1 1 1 1 AAA domain SKA2 PF16740.5 GAN08731.1 - 0.026 14.3 0.5 0.068 13.0 0.5 1.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 GerPC PF10737.9 GAN08731.1 - 0.041 14.0 1.7 7.2 6.6 0.0 2.7 1 1 1 2 2 2 0 Spore germination protein GerPC DUF4806 PF16064.5 GAN08731.1 - 0.13 12.5 2.9 0.38 11.1 0.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4806) IMD PF08397.11 GAN08731.1 - 0.26 10.7 6.4 0.34 10.2 5.8 1.5 1 1 0 1 1 1 0 IRSp53/MIM homology domain DUF1977 PF09320.11 GAN08732.1 - 1e-23 83.6 0.6 1e-23 83.6 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 GAN08732.1 - 3e-23 81.7 0.9 6.8e-23 80.6 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 GAN08732.1 - 0.00088 19.2 0.2 0.0065 16.5 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAN08732.1 - 0.1 12.5 1.7 0.53 10.2 0.0 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat INTS2 PF14750.6 GAN08733.1 - 1.2e-64 218.5 5.1 1.5e-64 218.2 5.1 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 eIF3m_C_helix PF18005.1 GAN08733.1 - 0.71 9.6 2.5 0.64 9.8 0.2 2.1 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Fibrillarin PF01269.17 GAN08735.1 - 5.3e-108 359.4 0.1 6.7e-108 359.0 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 GAN08735.1 - 5e-05 23.1 0.0 7.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 GAN08735.1 - 0.022 14.9 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 GAN08735.1 - 0.027 14.2 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 GAN08735.1 - 0.033 13.8 0.0 0.082 12.5 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF2462 PF09495.10 GAN08736.1 - 1.9e-18 67.0 14.5 2.9e-18 66.3 14.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Histone PF00125.24 GAN08737.1 - 3.1e-50 169.9 1.3 3.6e-50 169.7 1.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAN08737.1 - 3.3e-05 24.2 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAN08737.1 - 4.7e-05 23.5 0.4 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 GAN08737.1 - 0.0094 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 GAN08737.1 - 0.013 16.1 0.4 0.017 15.7 0.4 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 GAN08737.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN08737.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 GAN08738.1 - 2.6e-08 33.9 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 GAN08738.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 GAN08738.1 - 9.7e-05 22.7 0.1 0.00013 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 GAN08738.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAN08738.1 - 0.00035 20.8 0.1 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAN08738.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAN08738.1 - 0.059 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 GAN08738.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A FAM176 PF14851.6 GAN08739.1 - 6.5 6.4 9.3 5 6.8 8.0 1.5 1 1 0 1 1 1 0 FAM176 family Histone PF00125.24 GAN08740.1 - 9.6e-23 81.0 0.7 1.2e-22 80.7 0.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAN08740.1 - 6.1e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAN08740.1 - 0.0002 21.8 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 GAN08740.1 - 0.01 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein NDT80_PhoG PF05224.12 GAN08741.1 - 1.4e-39 136.2 0.1 1.4e-39 136.2 0.1 1.9 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family UME PF08064.13 GAN08742.1 - 0.0036 17.2 0.3 0.038 13.9 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain PRELI PF04707.14 GAN08744.1 - 9.9e-46 155.4 0.3 1.2e-45 155.1 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family bZIP_1 PF00170.21 GAN08745.1 - 9.2e-10 38.5 17.8 5.2e-09 36.1 17.3 2.3 1 1 0 1 1 1 1 bZIP transcription factor CCDC85 PF10226.9 GAN08745.1 - 3.6e-05 23.5 1.7 3.6e-05 23.5 1.7 1.9 2 0 0 2 2 2 1 CCDC85 family bZIP_2 PF07716.15 GAN08745.1 - 0.0089 16.1 20.4 2.9 8.0 19.9 2.6 1 1 1 2 2 2 1 Basic region leucine zipper Troponin PF00992.20 GAN08745.1 - 0.015 15.6 7.2 0.04 14.2 7.2 1.7 1 0 0 1 1 1 0 Troponin DUF1993 PF09351.10 GAN08745.1 - 0.047 13.8 1.1 0.099 12.8 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) tRNA-synt_1e PF01406.19 GAN08745.1 - 0.069 12.5 2.7 0.11 11.8 2.7 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ACCA PF03255.14 GAN08745.1 - 0.65 9.9 8.8 0.086 12.7 4.0 2.0 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Striatin PF08232.12 GAN08745.1 - 8.6 6.9 26.2 0.15 12.6 8.8 2.5 1 1 1 2 2 2 0 Striatin family DUF1688 PF07958.11 GAN08746.1 - 1.6e-151 504.8 0.0 1.9e-151 504.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TPR_10 PF13374.6 GAN08746.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat MMS19_C PF12460.8 GAN08747.1 - 2.5e-101 339.9 24.1 5.1e-101 338.8 14.3 3.7 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 GAN08747.1 - 1.9e-94 316.1 11.4 3.9e-93 311.8 0.2 4.6 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 GAN08747.1 - 1.8e-06 28.3 10.5 0.00075 20.0 0.8 5.9 3 1 2 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 GAN08747.1 - 4.6e-05 23.7 4.9 0.13 12.7 0.3 4.4 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 GAN08747.1 - 0.0037 17.4 7.6 0.021 15.1 0.2 5.1 6 0 0 6 6 6 1 HEAT repeat UME PF08064.13 GAN08747.1 - 0.02 14.8 1.4 15 5.5 0.0 4.4 5 0 0 5 5 5 0 UME (NUC010) domain ParcG PF10274.9 GAN08747.1 - 0.029 14.5 0.6 0.28 11.3 0.2 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Arm PF00514.23 GAN08747.1 - 0.035 14.2 7.0 0.55 10.4 0.3 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GBR_NSP5 PF17580.2 GAN08747.1 - 0.42 10.4 3.9 0.57 10.0 0.1 3.1 3 0 0 3 3 3 0 Group B Rotavirus Non-structural protein 5 Cnd1 PF12717.7 GAN08747.1 - 3.7 7.6 7.5 2.3 8.2 0.4 3.9 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Sugar_tr PF00083.24 GAN08748.1 - 1.4e-122 409.8 25.2 1.7e-122 409.5 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN08748.1 - 3.6e-25 88.7 54.5 4.1e-20 72.0 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN08748.1 - 0.0026 16.3 2.5 0.0026 16.3 2.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DDE_3 PF13358.6 GAN08749.1 - 1.1e-23 83.6 0.0 3.7e-21 75.4 0.0 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 GAN08749.1 - 0.00041 20.9 0.1 0.0012 19.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Stork_head PF10264.9 GAN08749.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain STI1 PF17830.1 GAN08749.1 - 0.13 12.2 0.0 6.4 6.8 0.0 2.6 2 1 1 3 3 3 0 STI1 domain Med26 PF08711.11 GAN08751.1 - 1.4e-07 31.4 0.0 3.8e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PRK PF00485.18 GAN08751.1 - 9e-06 25.6 0.0 3.1e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family PWWP PF00855.17 GAN08751.1 - 9.5e-06 25.9 1.9 2.1e-05 24.9 0.0 2.6 2 0 0 2 2 1 1 PWWP domain SRP54 PF00448.22 GAN08751.1 - 0.00016 21.4 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAN08751.1 - 0.00021 21.8 0.6 0.0016 18.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 GAN08751.1 - 0.00075 20.0 0.0 0.0042 17.6 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN08751.1 - 0.007 16.6 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 GAN08751.1 - 0.008 16.1 0.0 0.07 13.0 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 GAN08751.1 - 0.015 15.4 0.0 0.061 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAN08751.1 - 0.016 15.0 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 GAN08751.1 - 0.022 15.0 0.9 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAN08751.1 - 0.048 13.4 0.2 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAN08751.1 - 0.51 10.9 0.0 0.51 10.9 0.0 2.7 2 1 0 2 2 1 0 ABC transporter PI3K_1B_p101 PF10486.9 GAN08751.1 - 2.3 5.9 22.6 3.6 5.2 22.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PQ-loop PF04193.14 GAN08752.1 - 6.8e-29 99.4 9.4 1.3e-14 53.7 0.6 3.0 2 1 1 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 GAN08752.1 - 0.056 13.5 4.9 0.69 10.0 0.3 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Glyco_trans_2_3 PF13632.6 GAN08753.1 - 8.3e-15 55.2 0.5 8.3e-15 55.2 0.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 NTP_transf_2 PF01909.23 GAN08754.1 - 3.7e-07 30.4 0.0 2.3e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 GAN08754.1 - 2.6e-05 24.3 0.1 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 GAN08754.1 - 0.019 15.0 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase SNN_cytoplasm PF09051.10 GAN08755.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Stannin cytoplasmic RVT_1 PF00078.27 GAN08756.1 - 9e-25 87.5 0.0 1.4e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GAN08756.1 - 2.9e-13 49.7 0.0 1e-11 44.7 0.0 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN08756.1 - 0.00026 20.6 0.3 0.00082 18.9 0.3 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rnk_N PF14760.6 GAN08756.1 - 0.0087 16.5 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 Rnk N-terminus Retrotrans_gag PF03732.17 GAN08756.1 - 0.027 14.7 0.4 0.058 13.7 0.4 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein CAP PF00188.26 GAN08757.1 - 1.4e-14 55.0 3.9 3.6e-14 53.7 3.9 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family MRP-S28 PF10213.9 GAN08758.1 - 2.8e-39 134.4 1.8 4e-39 133.9 0.4 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF3461 PF11944.8 GAN08758.1 - 0.042 14.0 0.2 6.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Glyco_hydro_17 PF00332.18 GAN08759.1 - 8.7e-12 45.2 0.2 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 GST_C_3 PF14497.6 GAN08760.1 - 7.6e-13 48.5 0.5 4.9e-12 45.9 0.1 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN08760.1 - 0.00022 21.2 0.0 0.00071 19.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN08760.1 - 0.013 15.7 0.1 0.038 14.2 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAN08760.1 - 0.096 13.0 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BING4CT PF08149.11 GAN08761.1 - 9.2e-40 134.3 0.0 9.3e-38 127.9 0.0 3.3 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 GAN08761.1 - 2.1e-10 41.0 0.5 0.0001 23.0 0.0 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08761.1 - 3.7e-09 36.8 0.0 2.3 8.6 0.0 5.4 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 GAN08761.1 - 1.9e-05 23.9 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region PQQ_2 PF13360.6 GAN08761.1 - 0.0088 15.6 0.0 0.063 12.9 0.0 1.9 1 1 1 2 2 2 1 PQQ-like domain Ras PF00071.22 GAN08762.1 - 1.8e-46 157.7 0.0 1.2e-27 96.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAN08762.1 - 1.3e-11 44.8 0.0 1.1e-08 35.4 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN08762.1 - 0.11 11.9 0.0 0.52 9.8 0.0 1.8 1 1 1 2 2 2 0 ADP-ribosylation factor family TFX_C PF14601.6 GAN08762.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term DUF2232 PF09991.9 GAN08763.1 - 0.012 14.9 5.3 0.05 12.8 0.6 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2232) zf-ribbon_3 PF13248.6 GAN08763.1 - 0.17 11.3 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain CotH PF08757.11 GAN08764.1 - 1.1e-44 153.3 1.8 1.3e-43 149.8 3.6 1.8 2 0 0 2 2 2 1 CotH kinase protein Pam16 PF03656.13 GAN08764.1 - 6.2e-29 100.6 3.7 1.3e-28 99.6 3.7 1.5 1 0 0 1 1 1 1 Pam16 Synaptobrevin PF00957.21 GAN08765.1 - 7.9e-34 115.3 1.6 1.2e-33 114.8 1.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAN08765.1 - 4.9e-29 100.2 0.0 7.9e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain MCU PF04678.13 GAN08765.1 - 0.061 13.4 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Rhomboid PF01694.22 GAN08767.1 - 9.1e-32 110.1 9.9 9.1e-32 110.1 9.9 2.6 3 0 0 3 3 3 1 Rhomboid family HNF_C PF09354.10 GAN08767.1 - 0.25 12.4 1.6 1.8 9.7 0.0 2.9 2 1 1 3 3 3 0 HNF3 C-terminal domain Hexapep PF00132.24 GAN08768.1 - 5.8e-08 32.1 17.2 0.00013 21.5 4.8 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAN08768.1 - 0.0022 17.0 2.1 0.083 11.8 0.2 2.0 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.6 GAN08768.1 - 0.16 11.7 19.1 0.16 11.7 1.4 3.4 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Rhomboid PF01694.22 GAN08769.1 - 2.4e-29 102.3 9.4 3.9e-29 101.6 9.4 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 GAN08769.1 - 0.0037 17.8 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) MFS_1 PF07690.16 GAN08770.1 - 3.9e-37 128.0 29.5 3.9e-37 128.0 29.5 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN08770.1 - 4.7e-13 48.8 17.7 4.7e-13 48.8 17.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 GAN08770.1 - 7.6e-05 22.2 0.8 7.6e-05 22.2 0.8 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DSPc PF00782.20 GAN08771.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN08771.1 - 0.0035 17.0 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase VESA1_N PF12785.7 GAN08772.1 - 0.45 9.4 7.8 0.51 9.3 7.8 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 SOG2 PF10428.9 GAN08772.1 - 1.4 8.0 19.1 1.6 7.8 19.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DMT_YdcZ PF04657.13 GAN08773.1 - 2e-31 109.2 12.9 2.5e-31 108.8 12.9 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ TctB PF07331.11 GAN08773.1 - 0.036 14.3 13.5 0.048 13.9 13.5 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family ARA70 PF12489.8 GAN08773.1 - 0.15 12.3 2.9 0.2 11.9 2.9 1.1 1 0 0 1 1 1 0 Nuclear coactivator CDT1_C PF16679.5 GAN08775.1 - 0.064 13.7 1.4 4.3 7.8 0.1 2.6 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain pP_pnuc_1 PF18165.1 GAN08775.1 - 0.069 13.0 0.2 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease Polysacc_synt_4 PF04669.13 GAN08775.1 - 0.12 12.0 0.1 5.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis UNC80 PF15778.5 GAN08775.1 - 0.2 11.2 1.6 0.42 10.2 0.3 2.0 2 0 0 2 2 2 0 Cation channel complex component UNC80 Serum_albumin PF00273.20 GAN08775.1 - 0.52 10.1 3.6 0.41 10.4 0.8 2.0 2 0 0 2 2 2 0 Serum albumin family DUF724 PF05266.14 GAN08775.1 - 5.4 6.8 9.7 3.6 7.4 3.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) p450 PF00067.22 GAN08776.1 - 1.9e-82 277.5 0.2 2.4e-82 277.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Moricin PF06451.11 GAN08778.1 - 0.14 12.0 0.3 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Moricin Sec15 PF04091.12 GAN08779.1 - 1.8e-103 346.3 7.1 3.6e-103 345.3 7.1 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 GAN08779.1 - 0.00061 19.8 3.1 0.0025 17.8 0.0 3.6 4 0 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.11 GAN08779.1 - 0.0067 16.5 3.1 0.066 13.3 1.4 3.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 GAN08779.1 - 0.013 15.7 4.6 0.013 15.7 4.6 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2203 PF09969.9 GAN08779.1 - 0.63 10.8 5.5 4.1 8.1 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) BLI1 PF17324.2 GAN08779.1 - 1.9 9.2 5.9 16 6.2 0.1 3.7 4 0 0 4 4 4 0 BLOC-1 interactor 1 Fib_alpha PF08702.10 GAN08779.1 - 1.9 8.6 5.7 1.5 9.0 2.3 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DnaJ PF00226.31 GAN08780.1 - 8.3e-11 41.9 0.8 2.4e-10 40.4 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain DDE_Tnp_ISAZ013 PF07592.11 GAN08780.1 - 2.4 7.0 8.7 3.9 6.4 6.8 2.0 1 1 0 2 2 2 0 Rhodopirellula transposase DDE domain Med26 PF08711.11 GAN08781.1 - 0.0019 18.2 0.8 0.0041 17.1 0.8 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Torus PF16131.5 GAN08781.1 - 0.015 16.0 3.0 0.036 14.8 3.0 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 GAN08781.1 - 0.02 14.7 2.5 0.033 14.0 2.5 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 GAN08781.1 - 0.13 12.2 2.2 0.28 11.2 2.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAN08781.1 - 0.19 11.8 2.7 0.32 11.1 2.7 1.4 1 0 0 1 1 1 0 Zinc finger domain MFS_1 PF07690.16 GAN08782.1 - 5.8e-38 130.7 61.5 2.7e-30 105.5 36.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAN08782.1 - 4.5e-06 25.5 9.0 4.5e-06 25.5 9.0 2.9 1 1 1 3 3 3 3 MFS/sugar transport protein E1-E2_ATPase PF00122.20 GAN08782.1 - 0.89 9.0 4.8 0.35 10.4 1.1 2.2 2 0 0 2 2 2 0 E1-E2 ATPase RhoGEF PF00621.20 GAN08783.1 - 2.6e-39 135.3 2.2 5.8e-39 134.2 2.2 1.6 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 GAN08783.1 - 3.4e-31 107.3 0.1 7.9e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 GAN08783.1 - 1.3e-25 90.1 1.6 3.8e-25 88.5 1.6 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 GAN08783.1 - 8.2e-15 54.5 0.2 3.4e-14 52.5 0.2 2.2 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 GAN08783.1 - 3.5e-05 24.2 1.3 9.9e-05 22.8 0.5 2.2 2 0 0 2 2 2 1 PH domain Mito_carr PF00153.27 GAN08785.1 - 7.9e-62 205.2 2.9 1.4e-21 76.2 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein CAF1 PF04857.20 GAN08786.1 - 1.2e-81 274.4 1.0 1.2e-81 274.4 1.0 1.4 2 0 0 2 2 2 1 CAF1 family ribonuclease Glyco_hydro_3 PF00933.21 GAN08787.1 - 1e-66 225.5 0.1 1.4e-66 225.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAN08787.1 - 3.2e-39 135.0 0.0 5.6e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAN08787.1 - 4e-08 33.2 0.0 7.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain WHEP-TRS PF00458.20 GAN08787.1 - 0.015 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 WHEP-TRS domain fn3_5 PF06280.12 GAN08787.1 - 0.056 14.1 0.1 0.75 10.5 0.1 2.4 2 0 0 2 2 2 0 Fn3-like domain Pkinase_Tyr PF07714.17 GAN08788.1 - 2e-20 73.2 0.0 3.2e-20 72.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAN08788.1 - 2.6e-20 72.9 0.0 6.6e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Peptidase_C14 PF00656.22 GAN08789.1 - 8.6e-54 183.1 0.3 1.3e-53 182.6 0.3 1.2 1 0 0 1 1 1 1 Caspase domain Ank_2 PF12796.7 GAN08790.1 - 1e-17 64.5 0.2 1.6e-07 31.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN08790.1 - 3.6e-14 51.5 0.7 0.00011 22.4 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAN08790.1 - 1.4e-13 50.8 0.3 1.6e-06 28.2 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN08790.1 - 4.8e-13 49.3 0.2 0.00018 22.0 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAN08790.1 - 1.1e-09 38.2 1.2 0.0048 17.3 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat DUF4746 PF15928.5 GAN08790.1 - 8.9 5.6 9.8 0.38 10.1 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Chitin_synth_2 PF03142.15 GAN08791.1 - 5.8e-242 804.0 3.8 8e-242 803.5 3.8 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAN08791.1 - 8.1e-121 404.4 2.3 1.8e-119 399.9 2.3 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 GAN08791.1 - 1.5e-12 47.4 0.2 9.5e-06 25.7 0.0 3.7 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAN08791.1 - 5.3e-12 46.1 3.4 1.7e-11 44.4 3.4 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAN08791.1 - 8.9e-12 45.4 0.0 3.8e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 GAN08791.1 - 4e-06 26.7 0.3 3.3e-05 23.7 0.4 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.26 GAN08791.1 - 2.5e-05 24.2 0.0 0.0035 17.2 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN08791.1 - 0.0032 17.0 0.2 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 T2SSE PF00437.20 GAN08791.1 - 0.047 12.7 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GAN08791.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 GAN08792.1 - 1.3e-49 168.9 0.3 2.8e-49 167.7 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN08792.1 - 3.9e-18 65.8 0.0 1.3e-17 64.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAN08792.1 - 2.2e-10 40.2 3.0 2.9e-10 39.8 0.3 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAN08792.1 - 1.9e-08 34.5 0.2 1.1e-07 32.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 GAN08792.1 - 4.7e-08 32.8 0.9 9.9e-08 31.8 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 GAN08792.1 - 0.00024 20.9 15.4 0.00089 19.1 3.4 2.6 2 0 0 2 2 2 2 PHD-finger Cornifin PF02389.15 GAN08792.1 - 0.00076 19.7 4.3 0.00076 19.7 4.3 1.9 2 0 0 2 2 1 1 Cornifin (SPRR) family C1_1 PF00130.22 GAN08792.1 - 0.0009 19.1 20.0 0.003 17.4 4.4 3.1 2 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_19 PF13245.6 GAN08792.1 - 0.018 15.4 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zf_RING PF16744.5 GAN08792.1 - 0.025 14.7 15.5 0.3 11.2 0.9 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger zf-PHD-like PF15446.6 GAN08792.1 - 0.027 14.1 13.9 0.56 9.8 6.6 2.7 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF1087 PF06465.13 GAN08792.1 - 0.055 13.5 3.0 0.19 11.8 3.0 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) zf-RING-like PF08746.11 GAN08792.1 - 0.061 13.7 12.4 3.2 8.1 7.0 2.7 2 0 0 2 2 2 0 RING-like domain PHD_4 PF16866.5 GAN08792.1 - 0.066 13.3 17.0 0.063 13.4 7.1 3.0 2 0 0 2 2 2 0 PHD-finger ERCC3_RAD25_C PF16203.5 GAN08792.1 - 0.07 12.3 1.5 0.099 11.8 0.0 2.0 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_2 PF13639.6 GAN08792.1 - 0.47 10.8 12.2 4.7 7.6 1.5 2.7 2 0 0 2 2 2 0 Ring finger domain NTP_transferase PF00483.23 GAN08793.1 - 5.6e-50 170.2 0.0 8.4e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAN08793.1 - 3.6e-13 48.7 10.2 1.5e-10 40.4 3.1 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAN08793.1 - 1.6e-09 38.3 0.0 2.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 GAN08793.1 - 9.4e-05 22.1 4.5 9.4e-05 22.1 4.5 3.4 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 GAN08793.1 - 0.021 13.0 0.3 0.03 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 GAN08793.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.12 GAN08793.1 - 0.17 10.7 0.1 0.5 9.2 0.1 1.7 2 1 0 2 2 2 0 L-fucokinase Bact_lectin PF18483.1 GAN08795.1 - 6.8e-16 58.9 0.0 1.5e-15 57.7 0.0 1.6 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 GAN08795.1 - 1.8e-14 53.9 0.0 2.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.19 GAN08795.1 - 3.1e-12 46.9 0.3 6.9e-12 45.8 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 GAN08795.1 - 2.3e-10 40.3 2.9 4.4e-10 39.4 2.9 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PAW PF04721.17 GAN08795.1 - 9e-08 32.1 0.1 1.8e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Lectin_leg-like PF03388.13 GAN08795.1 - 1.6e-05 24.4 0.1 0.13 11.6 0.0 2.5 3 0 0 3 3 3 2 Legume-like lectin family CIA30 PF08547.12 GAN08797.1 - 5.4e-47 159.8 0.0 6.7e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 GAN08797.1 - 0.0063 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain Telomerase_RBD PF12009.8 GAN08799.1 - 1.7e-37 128.5 12.5 1.5e-36 125.4 5.5 2.8 2 0 0 2 2 2 2 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 GAN08799.1 - 0.00017 21.2 0.0 0.057 12.9 0.0 3.0 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Barstar PF01337.18 GAN08799.1 - 0.076 13.0 0.0 0.3 11.1 0.0 2.1 1 0 0 1 1 1 0 Barstar (barnase inhibitor) MMR_HSR1 PF01926.23 GAN08800.1 - 8.8e-15 54.8 0.0 4.7e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN08800.1 - 1.8e-07 31.2 0.1 6e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 GAN08800.1 - 8e-07 28.7 0.4 9.5e-05 22.0 0.3 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 GAN08800.1 - 0.00012 21.3 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 GAN08800.1 - 0.00016 21.1 0.2 0.00035 20.0 0.2 1.6 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 GAN08800.1 - 0.0016 18.6 0.0 0.28 11.4 0.0 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 GAN08800.1 - 0.0065 16.9 0.0 0.096 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.18 GAN08800.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin Ras PF00071.22 GAN08800.1 - 0.025 14.2 0.2 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Ras family Dynamin_N PF00350.23 GAN08800.1 - 0.026 14.6 6.0 0.37 10.8 0.1 2.8 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.9 GAN08800.1 - 0.042 13.6 0.1 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 GAN08800.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RRM_1 PF00076.22 GAN08801.1 - 1.8e-18 66.1 0.0 3.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1 PF02733.17 GAN08801.1 - 0.17 10.8 0.6 0.24 10.2 0.6 1.2 1 0 0 1 1 1 0 Dak1 domain TM2 PF05154.16 GAN08802.1 - 2.6e-15 56.5 7.5 2.6e-15 56.5 7.5 1.5 2 0 0 2 2 2 1 TM2 domain MCM PF00493.23 GAN08804.1 - 1.9e-101 337.8 0.0 3.6e-101 337.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAN08804.1 - 7.7e-35 119.5 0.1 1.6e-34 118.5 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAN08804.1 - 1.8e-27 95.6 2.4 5e-27 94.1 2.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAN08804.1 - 5.9e-16 58.9 0.4 1.3e-15 57.8 0.4 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAN08804.1 - 1.2e-05 24.8 0.0 0.00051 19.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAN08804.1 - 5.1e-05 23.3 0.0 0.00017 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAN08804.1 - 0.00019 21.3 0.0 0.0016 18.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAN08804.1 - 0.089 12.5 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Pex24p PF06398.11 GAN08805.1 - 5.4e-17 61.8 12.9 1.2e-16 60.6 12.9 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin tRNA-synt_1d PF00750.19 GAN08806.1 - 1.4e-92 310.3 5.1 1.8e-92 310.0 5.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAN08806.1 - 7.8e-26 90.6 0.0 2.7e-25 88.8 0.0 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain DUF1906 PF08924.11 GAN08806.1 - 0.035 14.3 0.2 0.15 12.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) SLATT_4 PF18186.1 GAN08807.1 - 0.036 13.7 1.0 0.066 12.9 1.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF2207 PF09972.9 GAN08808.1 - 0.24 10.1 0.0 0.24 10.1 0.0 3.3 1 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 GAN08808.1 - 0.27 11.1 0.1 0.27 11.1 0.1 3.4 2 1 3 5 5 5 0 Protein of unknown function (DUF2721) HAD_2 PF13419.6 GAN08809.1 - 8.7e-27 94.3 0.0 1.1e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN08809.1 - 1.1e-14 55.2 0.2 8.2e-13 49.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAN08809.1 - 0.00034 20.7 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN08809.1 - 0.0052 17.2 0.0 0.0064 16.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN08809.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like EF-hand_4 PF12763.7 GAN08810.1 - 4.5e-23 81.2 0.0 1.8e-12 47.1 0.0 3.0 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand Tmemb_14 PF03647.13 GAN08810.1 - 1.2e-22 80.4 6.4 2.5e-22 79.4 6.4 1.6 1 0 0 1 1 1 1 Transmembrane proteins 14C EF-hand_1 PF00036.32 GAN08810.1 - 6.2e-09 34.8 0.8 0.0041 16.6 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 GAN08810.1 - 2.9e-08 33.0 0.6 0.0025 17.6 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 GAN08810.1 - 4.8e-08 33.4 0.2 0.00051 20.4 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAN08810.1 - 3.4e-05 23.1 0.1 0.00024 20.5 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 GAN08810.1 - 0.00028 20.7 0.3 1.8 8.5 0.0 3.6 2 1 1 3 3 3 1 EF-hand domain pair DUF4407 PF14362.6 GAN08810.1 - 0.0036 16.7 6.5 0.0061 16.0 6.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) XkdW PF09636.10 GAN08810.1 - 0.004 17.2 2.0 0.0075 16.3 2.0 1.4 1 0 0 1 1 1 1 XkdW protein WD-3 PF09765.9 GAN08810.1 - 0.012 14.9 2.7 0.019 14.3 2.7 1.2 1 0 0 1 1 1 0 WD-repeat region Aim19 PF10315.9 GAN08810.1 - 0.17 12.2 2.6 0.52 10.6 0.7 2.7 2 2 0 2 2 2 0 Altered inheritance of mitochondria protein 19 Gpr1_Fun34_YaaH PF01184.19 GAN08811.1 - 4.5e-26 91.7 21.7 6.8e-26 91.2 21.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RRM_1 PF00076.22 GAN08812.1 - 0.00023 20.9 0.0 0.00061 19.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L27_C PF18471.1 GAN08812.1 - 0.0015 18.0 1.9 0.0022 17.4 1.9 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Nup35_RRM_2 PF14605.6 GAN08812.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EI24 PF07264.11 GAN08813.1 - 2e-23 83.6 6.7 3.9e-23 82.6 6.7 1.5 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PUF PF00806.19 GAN08813.1 - 3.7e-20 70.4 0.1 0.00027 20.5 0.1 7.5 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat Stealth_CR2 PF11380.8 GAN08813.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 Syja_N PF02383.18 GAN08814.1 - 2.1e-76 257.3 0.1 3.2e-76 256.7 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 GAN08814.1 - 4.1e-11 42.8 0.1 7.3e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family hDGE_amylase PF14701.6 GAN08815.1 - 3.6e-141 471.2 0.0 1.6e-111 373.6 0.0 2.2 1 1 1 2 2 2 2 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 GAN08815.1 - 7.2e-120 400.4 0.0 9.8e-120 400.0 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 GAN08815.1 - 3.7e-75 252.8 0.0 5.7e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 GAN08815.1 - 2e-14 53.5 0.0 4.6e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme PFU PF09070.11 GAN08815.1 - 0.052 13.8 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) SBF_like PF13593.6 GAN08816.1 - 9.6e-77 258.4 17.6 5e-70 236.3 15.7 2.1 1 1 1 2 2 2 2 SBF-like CPA transporter family (DUF4137) DUF5305 PF17231.2 GAN08816.1 - 0.17 11.3 0.9 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Tim17 PF02466.19 GAN08817.1 - 1.6e-05 25.2 5.4 0.00019 21.8 5.4 2.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AAA_32 PF13654.6 GAN08817.1 - 0.1 11.4 1.9 0.14 11.0 1.9 1.1 1 0 0 1 1 1 0 AAA domain DUF771 PF05595.11 GAN08817.1 - 0.58 10.2 3.9 3.7 7.6 1.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF771) TraT PF05818.12 GAN08817.1 - 2.4 7.8 6.7 2.3 7.8 0.7 2.2 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.9 GAN08817.1 - 3.6 7.8 10.5 11 6.2 0.5 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide AAA PF00004.29 GAN08818.1 - 6.5e-44 149.5 0.0 1.6e-43 148.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN08818.1 - 4e-12 45.7 0.1 1.1e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAN08818.1 - 1.3e-08 34.7 0.7 3.2e-08 33.4 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 GAN08818.1 - 3.2e-07 30.6 0.0 6.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAN08818.1 - 1.2e-06 28.5 0.1 6.4e-06 26.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN08818.1 - 2.1e-06 28.2 0.0 5.9e-05 23.5 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAN08818.1 - 1.4e-05 25.4 0.1 0.0082 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 GAN08818.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAN08818.1 - 0.0011 18.2 0.0 0.0027 17.0 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GAN08818.1 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAN08818.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAN08818.1 - 0.0025 18.3 0.1 0.02 15.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 GAN08818.1 - 0.0061 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAN08818.1 - 0.0064 15.9 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 GAN08818.1 - 0.0095 15.4 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 GAN08818.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAN08818.1 - 0.011 15.1 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 GAN08818.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAN08818.1 - 0.02 14.6 0.0 0.1 12.3 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 GAN08818.1 - 0.024 14.4 0.0 0.066 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAN08818.1 - 0.027 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 GAN08818.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAN08818.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAN08818.1 - 0.038 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RILP PF11461.8 GAN08818.1 - 0.039 14.2 1.2 0.089 13.0 1.2 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_25 PF13481.6 GAN08818.1 - 0.051 13.2 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAN08818.1 - 0.055 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 GAN08818.1 - 0.085 12.1 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 GAN08818.1 - 0.091 13.0 0.4 0.21 11.9 0.4 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_11 PF13086.6 GAN08818.1 - 0.092 12.5 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAN08818.1 - 0.11 12.8 0.0 0.44 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 GAN08819.1 - 4.2e-54 183.7 0.1 8.1e-54 182.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08819.1 - 5.9e-41 140.4 0.1 1.1e-40 139.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 GAN08819.1 - 3.6e-05 23.9 0.2 9.2e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kinase-like PF14531.6 GAN08819.1 - 0.006 15.9 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Laminin_II PF06009.12 GAN08819.1 - 0.016 15.2 2.0 0.029 14.4 0.4 2.3 2 1 0 2 2 2 0 Laminin Domain II RGCC PF15151.6 GAN08819.1 - 0.035 14.3 3.0 0.074 13.3 2.4 1.8 1 1 0 1 1 1 0 Response gene to complement 32 protein family Phlebovirus_NSM PF07246.11 GAN08819.1 - 0.062 12.7 3.3 0.12 11.8 3.3 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Tropomyosin_1 PF12718.7 GAN08819.1 - 0.18 11.9 7.6 0.48 10.6 7.6 1.7 1 0 0 1 1 1 0 Tropomyosin like Fzo_mitofusin PF04799.13 GAN08819.1 - 0.36 10.4 1.6 0.73 9.4 1.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region Exonuc_VII_L PF02601.15 GAN08819.1 - 1.1 8.7 6.9 0.47 10.0 3.8 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Uds1 PF15456.6 GAN08819.1 - 3.5 7.8 13.0 4.6 7.4 5.6 3.1 2 1 1 3 3 3 0 Up-regulated During Septation Bystin PF05291.11 GAN08820.1 - 1.9e-97 326.1 1.3 2.1e-97 325.9 1.3 1.0 1 0 0 1 1 1 1 Bystin AA_kinase PF00696.28 GAN08821.1 - 3.4e-41 141.4 1.3 6.3e-41 140.6 0.9 1.6 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 GAN08821.1 - 1.1e-15 57.3 0.0 3.4e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 PUA domain Queuosine_synth PF02547.15 GAN08821.1 - 0.053 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein Nucleotid_trans PF03407.16 GAN08821.1 - 0.18 11.8 0.0 0.73 9.8 0.0 1.9 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase RabGAP-TBC PF00566.18 GAN08822.1 - 2.7e-56 190.6 0.1 2.7e-56 190.6 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Laminin_I PF06008.14 GAN08822.1 - 0.021 14.6 14.2 0.059 13.1 14.2 1.7 1 0 0 1 1 1 0 Laminin Domain I Leu_zip PF15294.6 GAN08822.1 - 0.17 11.4 19.8 0.51 9.8 19.8 1.8 1 1 0 1 1 1 0 Leucine zipper GAS PF13851.6 GAN08822.1 - 0.18 11.1 22.0 0.65 9.3 22.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 GAN08822.1 - 0.39 10.8 16.3 0.033 14.3 6.7 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 GAN08822.1 - 0.44 10.6 7.5 1.1 9.3 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 GAN08822.1 - 0.51 10.4 20.5 2.4 8.2 12.7 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.9 GAN08822.1 - 0.66 10.3 16.1 0.034 14.4 9.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 GAN08822.1 - 0.72 9.9 6.8 0.17 11.9 2.9 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus She9_MDM33 PF05546.11 GAN08822.1 - 1.1 9.1 9.5 0.3 10.9 3.9 2.2 1 1 1 2 2 2 0 She9 / Mdm33 family DUF4472 PF14739.6 GAN08822.1 - 1.8 9.3 24.3 0.04 14.6 11.9 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4472) ADIP PF11559.8 GAN08822.1 - 1.9 8.6 18.3 4.1 7.5 11.7 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 GAN08822.1 - 3 8.5 12.9 3.4 8.3 0.9 2.8 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 GAN08822.1 - 4.5 7.8 27.1 1.9 9.0 15.3 3.5 2 1 0 3 3 3 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 GAN08822.1 - 5 7.2 24.5 0.94 9.5 17.5 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 GAN08822.1 - 9 5.5 8.9 18 4.5 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 GAN08822.1 - 9.4 6.8 30.6 0.13 12.8 16.4 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF775 PF05603.12 GAN08823.1 - 4.3e-60 202.7 0.0 4.9e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Peptidase_C97 PF05903.14 GAN08824.1 - 7.1e-42 142.8 0.0 1.2e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 GAN08824.1 - 5.1e-27 94.8 4.6 5.1e-27 94.8 4.6 1.5 2 0 0 2 2 2 1 PUL domain Thioredoxin PF00085.20 GAN08824.1 - 7.9e-13 48.3 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAN08824.1 - 1.9e-05 25.1 0.1 0.00053 20.4 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 GAN08824.1 - 0.00069 19.8 0.1 1.1 9.4 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin Redoxin PF08534.10 GAN08824.1 - 0.0019 17.9 0.0 0.007 16.1 0.0 1.9 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 GAN08824.1 - 0.0063 16.4 0.0 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 GAN08824.1 - 0.034 14.3 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 GAN08824.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Methyltransf_25 PF13649.6 GAN08826.1 - 2.1e-09 38.0 0.0 5.4e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN08826.1 - 5.7e-09 36.5 0.0 1.3e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08826.1 - 2.3e-08 34.0 0.0 6.5e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN08826.1 - 4.2e-05 24.2 0.2 0.00015 22.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08826.1 - 0.00028 20.7 0.0 0.0021 17.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN08826.1 - 0.0015 18.1 0.0 0.0038 16.7 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase SR-25 PF10500.9 GAN08826.1 - 0.14 11.7 4.9 0.44 10.1 4.9 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 GAN08826.1 - 2 7.1 4.1 2.7 6.7 4.1 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 GAN08826.1 - 3.7 5.8 9.7 6.7 4.9 9.7 1.4 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 GAN08826.1 - 7.3 5.0 11.1 11 4.4 11.1 1.2 1 0 0 1 1 1 0 Macoilin family Cyt-b5 PF00173.28 GAN08827.1 - 2e-22 79.1 0.0 2.3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 GAN08827.1 - 0.06 13.5 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Myb_DNA-bind_6 PF13921.6 GAN08828.1 - 6.5e-07 29.5 0.2 2.1e-06 27.9 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN08828.1 - 3.5e-05 23.9 0.2 7.7e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aa_trans PF01490.18 GAN08829.1 - 1.2e-92 310.8 27.7 1.4e-92 310.5 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAN08829.1 - 4.8e-09 35.7 16.5 4.8e-09 35.7 16.5 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Adeno_E3_14_5 PF04834.12 GAN08829.1 - 0.029 14.9 2.0 0.085 13.4 0.2 2.8 2 1 0 2 2 2 0 Early E3 14.5 kDa protein SieB PF14163.6 GAN08829.1 - 2.3 7.7 5.9 5.8 6.4 0.2 2.8 2 0 0 2 2 2 0 Super-infection exclusion protein B TEA PF01285.18 GAN08830.1 - 1.8e-31 108.0 0.0 4e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain YBD PF17725.1 GAN08830.1 - 7.2e-08 32.5 1.0 1.4e-07 31.6 1.0 1.4 1 0 0 1 1 1 1 YAP binding domain RRM_1 PF00076.22 GAN08831.1 - 9.9e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DIOX_N PF14226.6 GAN08831.1 - 0.094 13.5 1.1 0.13 13.0 0.6 1.5 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Zn_clus PF00172.18 GAN08832.1 - 4.1e-16 58.8 31.7 1.4e-08 34.7 11.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 GAN08833.1 - 2.3e-45 155.1 0.1 2.3e-45 155.1 0.1 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08833.1 - 3e-15 56.2 0.5 1.5e-12 47.4 0.5 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.22 GAN08833.1 - 1.6e-05 24.3 3.5 4.3e-05 22.9 3.5 1.7 1 0 0 1 1 1 1 ZIP Zinc transporter Sec23_trunk PF04811.15 GAN08835.1 - 7.4e-60 202.5 0.0 1.3e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAN08835.1 - 1.6e-23 82.5 0.0 4e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAN08835.1 - 6e-16 59.0 0.0 1.6e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAN08835.1 - 3e-15 56.0 7.4 6e-15 55.0 7.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAN08835.1 - 4.6e-11 42.5 0.0 2.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat TFIIA PF03153.13 GAN08835.1 - 0.67 9.9 43.4 1.3 9.0 43.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 GAN08836.1 - 0.047 12.7 2.6 0.057 12.4 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.6 GAN08836.1 - 0.073 13.4 2.3 0.15 12.5 2.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GET2 PF08690.10 GAN08836.1 - 0.11 12.1 8.7 0.14 11.8 8.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1840 PF08895.11 GAN08836.1 - 0.99 9.8 4.5 3.5 8.0 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) Zap1_zf2 PF18217.1 GAN08836.1 - 5.2 7.2 13.2 0.4 10.7 2.7 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 LIN52 PF10044.9 GAN08837.1 - 0.15 12.8 0.1 0.16 12.7 0.1 1.1 1 0 0 1 1 1 0 Retinal tissue protein UQ_con PF00179.26 GAN08838.1 - 9.9e-49 164.6 0.1 1.1e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAN08838.1 - 0.00019 21.1 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAN08838.1 - 0.04 14.2 1.3 0.051 13.9 1.3 1.4 1 1 0 1 1 1 0 RWD domain Velvet PF11754.8 GAN08839.1 - 3.6e-38 131.9 4.4 3.8e-27 95.8 1.0 3.3 1 1 2 3 3 3 2 Velvet factor BAG PF02179.16 GAN08840.1 - 3.1e-11 43.5 0.4 3.1e-11 43.5 0.4 3.7 3 2 0 3 3 3 1 BAG domain F-box-like PF12937.7 GAN08843.1 - 9.2e-08 31.9 1.3 2.4e-07 30.5 1.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN08843.1 - 0.37 11.3 9.5 4.9 7.7 0.3 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) eIF2A PF08662.11 GAN08844.1 - 1.2e-38 132.9 8.4 5.3e-35 121.1 0.8 5.3 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GAN08844.1 - 6.4e-05 22.7 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 GAN08844.1 - 0.0003 21.5 1.5 0.032 15.1 0.6 4.0 2 1 1 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN08844.1 - 0.0022 18.2 0.1 34 4.8 0.0 5.9 6 2 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain DegQ PF08181.11 GAN08844.1 - 0.18 11.9 1.3 0.41 10.8 1.3 1.6 1 0 0 1 1 1 0 DegQ (SacQ) family Ribosomal_L4 PF00573.22 GAN08845.1 - 9e-42 142.9 0.9 9e-42 142.9 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAN08845.1 - 0.00066 19.7 1.4 0.0017 18.4 0.1 2.3 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain USP8_dimer PF08969.11 GAN08846.1 - 2.7e-17 63.0 0.3 4.5e-17 62.3 0.3 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain DIOX_N PF14226.6 GAN08847.1 - 3.7e-23 82.5 0.2 7.2e-23 81.6 0.2 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAN08847.1 - 5.6e-19 68.5 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UDPGT PF00201.18 GAN08848.1 - 1.1e-09 37.6 0.2 1.4e-09 37.3 0.2 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN08848.1 - 0.0001 22.3 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Clat_adaptor_s PF01217.20 GAN08849.1 - 4.2e-54 182.3 2.8 4.8e-54 182.1 2.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.21 GAN08850.1 - 3.4e-47 161.1 0.0 4.8e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family YdjC PF04794.12 GAN08850.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 YdjC-like protein Cyclase PF04199.13 GAN08853.1 - 2.5e-15 56.9 0.0 3.1e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase SWIB PF02201.18 GAN08854.1 - 7.6e-23 80.2 0.1 1.6e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 GAN08854.1 - 1.2e-14 53.9 0.2 3.3e-14 52.5 0.1 1.8 2 0 0 2 2 2 1 DEK C terminal domain Zip PF02535.22 GAN08855.1 - 6.2e-58 196.6 14.0 9.4e-57 192.7 14.0 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter ORC6 PF05460.13 GAN08855.1 - 0.017 14.4 0.1 0.022 14.0 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) UPF0113 PF03657.13 GAN08855.1 - 0.052 13.8 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 UPF0113 PUA domain EAF PF09816.9 GAN08856.1 - 5.9e-11 42.7 1.1 5.9e-11 42.7 1.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor TT_ORF2 PF02957.15 GAN08856.1 - 1.7 9.6 14.9 1.4 9.9 0.5 3.8 3 1 0 4 4 4 0 TT viral ORF2 GEMIN8 PF15348.6 GAN08856.1 - 4.7 7.4 10.2 0.95 9.7 2.1 2.6 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 CDK5_activator PF03261.15 GAN08857.1 - 1.1 8.7 7.5 1.4 8.4 7.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.13 GAN08857.1 - 8.8 6.2 18.7 12 5.7 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 GAN08858.1 - 1.1e-53 182.0 2.0 1.1e-53 182.0 2.0 3.2 2 2 0 2 2 2 1 Gti1/Pac2 family E1-E2_ATPase PF00122.20 GAN08859.1 - 2e-45 154.5 4.3 2e-45 154.5 4.3 3.4 5 1 1 6 6 6 1 E1-E2 ATPase Hydrolase PF00702.26 GAN08859.1 - 1.2e-22 81.3 0.4 6e-22 79.0 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN08859.1 - 2.9e-10 39.7 0.0 8.6e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN08859.1 - 0.00014 21.7 0.1 0.00079 19.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2818 PF10993.8 GAN08859.1 - 0.066 13.8 1.3 0.25 11.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) Ribosomal_L14 PF00238.19 GAN08861.1 - 9e-36 122.6 0.2 1.1e-35 122.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ank_2 PF12796.7 GAN08862.1 - 5.4e-48 161.5 13.2 7e-20 71.4 0.2 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN08862.1 - 3.2e-40 136.0 7.1 4.8e-14 52.5 0.1 5.6 5 1 2 7 7 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAN08862.1 - 1.6e-31 107.3 5.8 0.0004 20.7 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 GAN08862.1 - 2e-27 94.9 10.3 1.5e-08 34.7 0.1 6.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN08862.1 - 2.2e-27 92.1 6.7 0.0065 16.9 0.0 8.9 9 0 0 9 9 8 7 Ankyrin repeat GDPD PF03009.17 GAN08862.1 - 6e-24 85.2 0.0 4.7e-23 82.2 0.0 2.3 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.19 GAN08862.1 - 4.6e-20 72.9 23.1 4.5e-10 40.0 3.1 4.0 2 1 2 4 4 4 3 SPX domain Sporozoite_P67 PF05642.11 GAN08862.1 - 0.0075 14.4 7.8 0.014 13.6 7.8 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Mucin PF01456.17 GAN08862.1 - 1.6 8.7 29.5 3.4 7.6 29.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 GAN08862.1 - 3.2 8.2 14.9 7.5 7.0 12.5 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 GAN08862.1 - 7.8 6.7 18.2 17 5.6 18.2 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Polysacc_deac_1 PF01522.21 GAN08863.1 - 4.8e-26 91.1 0.1 8.7e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2057 PF09829.9 GAN08863.1 - 8.2 6.5 9.6 0.57 10.3 4.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) COX7C PF02935.16 GAN08864.1 - 1.4e-16 60.5 0.1 1.6e-16 60.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Herpes_gE PF02480.16 GAN08865.1 - 0.00072 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DAG1 PF05454.11 GAN08865.1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Shisa PF13908.6 GAN08865.1 - 0.029 14.6 3.4 0.056 13.7 0.0 2.9 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Kelch_6 PF13964.6 GAN08865.1 - 0.031 14.6 0.2 4.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Kelch motif EphA2_TM PF14575.6 GAN08865.1 - 0.036 14.9 0.0 0.15 12.9 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.11 GAN08865.1 - 0.088 12.8 0.1 0.088 12.8 0.1 2.9 4 0 0 4 4 4 0 Human adenovirus early E3A glycoprotein Stevor PF17410.2 GAN08865.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Tyr_Deacylase PF02580.16 GAN08867.1 - 0.042 14.4 4.5 0.051 14.1 4.5 1.2 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase ATG27 PF09451.10 GAN08867.1 - 0.68 9.7 6.1 0.75 9.6 6.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF3496 PF12001.8 GAN08867.1 - 2.3 8.6 17.2 0.75 10.2 13.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Mog1 PF04603.12 GAN08867.1 - 9.4 6.6 10.3 12 6.3 10.1 1.3 1 1 0 1 1 1 0 Ran-interacting Mog1 protein Rhomboid PF01694.22 GAN08869.1 - 2.2e-21 76.4 3.5 3.6e-21 75.7 3.5 1.3 1 0 0 1 1 1 1 Rhomboid family FAD_binding_6 PF00970.24 GAN08870.1 - 8.2e-34 115.9 0.0 1.3e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAN08870.1 - 4e-33 114.3 0.0 5.7e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAN08870.1 - 3e-05 24.2 0.0 0.00035 20.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SMP PF04927.12 GAN08871.1 - 0.00018 21.9 0.6 0.00027 21.3 0.6 1.3 1 0 0 1 1 1 1 Seed maturation protein LigB PF02900.18 GAN08872.1 - 1.4e-29 103.1 0.0 1.7e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3128 PF11326.8 GAN08873.1 - 0.31 11.5 12.7 2.4 8.6 9.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) Mhr1 PF12829.7 GAN08874.1 - 4.1e-13 49.2 0.4 6.8e-13 48.5 0.4 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination RPT PF13446.6 GAN08874.1 - 0.08 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein MHB PF16525.5 GAN08874.1 - 0.13 12.5 0.5 0.55 10.5 0.1 2.0 1 1 1 2 2 2 0 Haemophore, haem-binding Uds1 PF15456.6 GAN08875.1 - 9.6e-23 80.8 9.9 9.6e-23 80.8 9.9 7.6 4 1 3 7 7 7 1 Up-regulated During Septation CENP-F_leu_zip PF10473.9 GAN08875.1 - 0.0001 22.3 15.8 0.0001 22.3 15.8 7.3 4 3 1 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 GAN08875.1 - 0.0065 16.8 0.5 0.0065 16.8 0.5 9.9 9 2 1 10 10 10 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2935 PF11155.8 GAN08875.1 - 0.41 11.0 24.0 0.17 12.2 1.6 5.6 4 2 1 5 5 5 0 Domain of unknown function (DUF2935) ArfGap PF01412.18 GAN08876.1 - 4.1e-33 113.9 1.7 8.7e-33 112.9 0.0 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 GAN08876.1 - 2.1e-17 63.6 7.9 2.1e-17 63.6 7.9 2.1 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 GAN08876.1 - 6.1e-14 52.4 1.3 1.4e-13 51.3 0.2 2.3 2 0 0 2 2 2 1 PH domain DUF1664 PF07889.12 GAN08876.1 - 1.2 9.2 3.5 4.1 7.4 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Bromodomain PF00439.25 GAN08877.1 - 5.1e-41 138.6 3.3 3.5e-22 78.3 0.1 2.8 3 0 0 3 3 3 2 Bromodomain PDCD2_C PF04194.13 GAN08879.1 - 1.7e-38 132.4 1.0 1.7e-38 132.4 1.0 3.0 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 GAN08879.1 - 4.2e-07 29.9 8.7 4.2e-07 29.9 8.7 3.5 3 2 0 3 3 3 1 MYND finger DUF1460 PF07313.12 GAN08879.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) E7 PF00527.18 GAN08879.1 - 0.72 10.1 11.4 2.3 8.5 0.2 3.9 3 1 0 3 3 3 0 E7 protein, Early protein zf-Mss51 PF13824.6 GAN08879.1 - 0.82 9.8 9.3 0.085 13.0 2.9 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 CENP-B_dimeris PF09026.10 GAN08880.1 - 1.8 9.0 9.8 12 6.3 4.3 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sec2p PF06428.11 GAN08881.1 - 7.8e-16 57.8 10.4 7.8e-16 57.8 10.4 1.9 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF2408 PF10303.9 GAN08881.1 - 0.013 16.0 2.5 0.018 15.6 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Exonuc_VII_L PF02601.15 GAN08881.1 - 0.14 11.7 3.5 0.28 10.7 3.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 GAN08881.1 - 0.15 12.2 13.3 0.3 11.3 13.3 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 GAN08881.1 - 0.18 11.2 10.7 0.28 10.5 10.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RPW8 PF05659.11 GAN08881.1 - 0.33 10.6 3.0 0.59 9.8 3.0 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 V_ATPase_I PF01496.19 GAN08881.1 - 1.5 6.7 6.9 2.1 6.1 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.12 GAN08881.1 - 3.2 7.8 7.0 10 6.1 2.8 2.2 1 1 1 2 2 2 0 Laminin Domain II PX PF00787.24 GAN08882.1 - 6.4e-21 74.4 1.3 9e-21 74.0 0.1 1.9 2 0 0 2 2 2 1 PX domain DUF1041 PF06292.17 GAN08882.1 - 0.87 10.0 6.4 3.6 8.0 0.8 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1041) FAM92 PF06730.11 GAN08882.1 - 2.6 7.4 11.8 0.0099 15.3 2.8 1.5 2 0 0 2 2 2 0 FAM92 protein Sterol_MT_C PF08498.10 GAN08883.1 - 7.6e-29 99.8 1.6 1.4e-28 99.0 1.6 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAN08883.1 - 6.5e-20 71.6 0.0 2e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN08883.1 - 3.8e-18 66.0 0.0 1.4e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08883.1 - 3e-17 62.8 0.0 4.7e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08883.1 - 4.5e-11 42.9 0.0 7.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN08883.1 - 1.7e-10 40.6 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN08883.1 - 2.4e-10 41.0 0.0 8.5e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GAN08883.1 - 5.3e-10 39.0 0.1 7.7e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAN08883.1 - 0.0058 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 GAN08883.1 - 0.05 13.2 0.0 0.088 12.4 0.0 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 GAN08883.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.5 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAN08883.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain STE PF02200.16 GAN08884.1 - 8.5e-55 183.9 0.0 1.8e-54 182.8 0.0 1.6 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 GAN08884.1 - 2e-08 34.3 17.1 0.00017 21.9 3.5 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN08884.1 - 8.9e-06 26.1 11.9 0.016 16.0 1.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN08884.1 - 0.0017 18.7 5.8 0.0017 18.7 5.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAN08884.1 - 0.023 14.7 3.0 0.023 14.7 3.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger IBR PF01485.21 GAN08884.1 - 2.7 8.3 6.6 2.2 8.6 4.4 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Sporozoite_P67 PF05642.11 GAN08884.1 - 3 5.8 13.2 6.2 4.8 13.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PH_9 PF15410.6 GAN08886.1 - 2.5e-35 121.4 0.3 1e-34 119.4 0.3 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 GAN08886.1 - 5.2e-30 104.5 0.9 1.1e-29 103.4 0.1 1.9 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 GAN08886.1 - 1.2e-06 29.0 0.1 3.1e-05 24.4 0.1 2.7 1 1 0 1 1 1 1 PH domain Nucleotid_trans PF03407.16 GAN08887.1 - 4e-16 59.6 2.3 5.7e-16 59.1 2.3 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase HTH_WhiA PF02650.14 GAN08888.1 - 0.021 15.1 1.0 0.06 13.7 1.0 1.7 1 0 0 1 1 1 0 WhiA C-terminal HTH domain PMEI PF04043.15 GAN08888.1 - 0.12 12.7 2.5 0.26 11.6 2.5 1.6 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor MoCF_biosynth PF00994.24 GAN08889.1 - 4.6e-22 78.2 0.0 7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF1803 PF08820.10 GAN08889.1 - 0.03 14.3 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) zf-CCCH_2 PF14608.6 GAN08890.1 - 2.7e-05 24.4 2.9 2.7e-05 24.4 2.9 2.1 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 GAN08890.1 - 0.00011 22.1 3.3 0.00011 22.1 3.3 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 GAN08890.1 - 0.00041 20.1 1.1 0.00041 20.1 1.1 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 GAN08890.1 - 0.0039 17.1 0.5 0.0039 17.1 0.5 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_32 PF13679.6 GAN08890.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain zf-primase PF09329.11 GAN08890.1 - 0.12 12.2 1.0 0.23 11.3 1.0 1.4 1 0 0 1 1 1 0 Primase zinc finger UPF0203 PF05254.12 GAN08891.1 - 8.9e-28 96.4 1.8 1.1e-27 96.0 1.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 GAN08891.1 - 9.8e-05 22.5 0.3 0.00016 21.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 GAN08891.1 - 0.0011 19.2 1.0 0.0028 17.9 1.1 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 GAN08891.1 - 0.014 15.6 1.1 0.14 12.3 0.1 2.2 2 0 0 2 2 2 0 CHCH domain DUF5339 PF17274.2 GAN08891.1 - 0.018 15.9 3.7 0.42 11.5 1.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Cmc1 PF08583.10 GAN08891.1 - 0.026 14.5 4.0 0.6 10.2 0.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF5100 PF17029.5 GAN08891.1 - 0.08 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) DUF3128 PF11326.8 GAN08891.1 - 0.12 12.8 3.3 0.67 10.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) GPAT_N PF14829.6 GAN08891.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.5 1 1 1 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal Pet191_N PF10203.9 GAN08891.1 - 0.24 11.7 2.6 8 6.8 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 RRM_1 PF00076.22 GAN08892.1 - 2.4e-17 62.5 0.0 3.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M48 PF01435.18 GAN08894.1 - 4.2e-17 62.6 0.0 7.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 TPR_2 PF07719.17 GAN08894.1 - 0.075 13.2 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DELLA PF12041.8 GAN08894.1 - 0.1 12.5 0.4 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal TPR_8 PF13181.6 GAN08894.1 - 0.13 12.5 0.0 0.63 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN08894.1 - 0.18 12.1 0.2 0.36 11.1 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Auto_anti-p27 PF06677.12 GAN08895.1 - 1.4e-28 98.8 3.1 2.4e-14 53.2 0.4 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CxC6 PF18721.1 GAN08895.1 - 0.0033 17.7 0.0 0.0033 17.7 0.0 2.5 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases DUF4692 PF15763.5 GAN08895.1 - 0.0038 17.7 0.8 0.0076 16.7 0.8 1.4 1 0 0 1 1 1 1 Regulator of human erythroid cell expansion (RHEX) DUF3736 PF12540.8 GAN08895.1 - 0.012 15.8 2.6 0.044 13.9 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3736) DEAD PF00270.29 GAN08896.1 - 2.5e-21 76.2 0.1 8.3e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 GAN08896.1 - 3.4e-18 65.5 0.0 9.5e-18 64.1 0.0 1.8 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 GAN08896.1 - 8.6e-18 64.8 4.8 8.6e-18 64.8 4.8 2.2 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 GAN08896.1 - 8.8e-17 61.5 0.0 2e-15 57.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 GAN08896.1 - 4.5e-09 36.2 0.0 9.8e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 GAN08896.1 - 8.6e-08 32.4 0.0 4.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_Sgs1 PF11408.8 GAN08896.1 - 0.00069 19.6 0.0 0.0061 16.6 0.0 2.3 2 0 0 2 2 2 1 Sgs1 RecQ helicase Seryl_tRNA_N PF02403.22 GAN08896.1 - 0.0022 18.2 4.7 0.0022 18.2 4.7 2.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain WXG100 PF06013.12 GAN08896.1 - 0.023 14.9 4.6 0.099 12.9 4.6 2.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG OmpH PF03938.14 GAN08896.1 - 0.044 14.1 4.7 0.63 10.4 1.9 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2935 PF11155.8 GAN08896.1 - 0.049 14.0 0.2 0.17 12.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) TSNAXIP1_N PF15739.5 GAN08896.1 - 0.15 12.4 4.7 0.5 10.8 4.7 1.9 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TPR_MLP1_2 PF07926.12 GAN08896.1 - 6.7 6.8 10.5 0.47 10.5 4.8 2.1 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein KDZ PF18758.1 GAN08897.1 - 0.015 14.9 1.1 0.016 14.8 1.1 1.3 1 1 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Rrp44_CSD1 PF17216.3 GAN08897.1 - 4.5 7.0 6.7 6.6 6.4 5.6 1.7 1 1 0 1 1 1 0 Rrp44-like cold shock domain E1-E2_ATPase PF00122.20 GAN08898.1 - 2.8e-40 137.8 2.2 2.8e-40 137.8 2.2 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAN08898.1 - 6.1e-40 136.9 5.1 6.1e-40 136.9 5.1 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAN08898.1 - 5.2e-22 79.2 0.0 1.3e-09 38.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN08898.1 - 2.2e-21 75.7 0.0 3.9e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN08898.1 - 2.6e-06 27.0 0.1 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN08898.1 - 7.2e-05 22.6 0.2 0.00016 21.5 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAN08898.1 - 0.021 15.2 0.0 0.99 9.8 0.0 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 GAN08898.1 - 0.043 12.6 0.4 6.4 5.4 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM72 PF16054.5 GAN08899.1 - 0.07 12.8 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein family 72 Lipoprotein_10 PF03202.13 GAN08899.1 - 0.34 11.4 3.5 0.39 11.2 0.8 2.2 1 1 1 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region LytR_C PF13399.6 GAN08899.1 - 4.2 8.4 8.0 1.1 10.4 2.2 2.8 2 1 1 3 3 3 0 LytR cell envelope-related transcriptional attenuator Lipase_3 PF01764.25 GAN08900.1 - 3.5e-07 30.2 0.0 6.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAN08900.1 - 0.0025 17.1 0.1 0.0059 15.9 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN08900.1 - 0.01 16.4 0.1 0.022 15.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 GAN08900.1 - 0.043 13.7 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 GAN08900.1 - 0.08 12.5 0.3 0.19 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 GAN08900.1 - 0.099 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-C2H2 PF00096.26 GAN08901.1 - 8.2e-07 29.1 7.5 0.0026 18.1 1.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN08901.1 - 1.3e-05 25.7 6.6 0.036 14.9 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 GAN08901.1 - 0.0031 18.1 1.8 0.38 11.4 0.2 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 GAN08901.1 - 0.016 15.5 2.4 0.24 11.7 2.3 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 GAN08901.1 - 0.084 12.9 5.6 0.74 9.9 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger FYDLN_acid PF09538.10 GAN08901.1 - 0.11 13.2 6.2 1.2 9.8 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf_C2H2_ZHX PF18387.1 GAN08901.1 - 0.18 11.4 1.2 0.35 10.5 1.2 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 GAN08901.1 - 1 9.9 3.7 6.9 7.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.25 GAN08902.1 - 2.3e-45 155.0 0.0 4.4e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08902.1 - 5.3e-20 71.8 0.0 1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN08902.1 - 0.0005 20.1 0.1 0.0016 18.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family SNAP PF14938.6 GAN08903.1 - 9.1e-77 258.2 9.9 1e-76 258.1 9.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GAN08903.1 - 0.0013 19.0 11.4 0.2 12.0 0.8 2.8 2 2 0 2 2 2 2 Tetratricopeptide repeat XPB_DRD PF18458.1 GAN08903.1 - 0.013 15.4 0.3 0.025 14.4 0.3 1.5 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain TPR_2 PF07719.17 GAN08903.1 - 0.035 14.2 18.3 1.9 8.8 0.1 6.0 4 1 2 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 GAN08903.1 - 0.069 12.3 1.5 0.12 11.5 0.9 1.6 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_7 PF13176.6 GAN08903.1 - 0.16 12.1 7.0 0.94 9.7 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAN08903.1 - 2.8 9.0 11.2 7.3 7.7 1.1 4.4 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAN08903.1 - 7.8 7.2 14.3 66 4.3 4.0 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat G-alpha PF00503.20 GAN08904.1 - 1.1e-89 301.1 4.4 9.2e-59 199.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 GAN08904.1 - 7.7e-08 32.0 4.3 0.0049 16.3 0.1 3.1 3 1 0 3 3 3 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 GAN08904.1 - 0.0033 16.8 0.1 0.0063 15.9 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DAP3 PF10236.9 GAN08904.1 - 0.072 12.2 0.5 0.14 11.3 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 GAN08904.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RibD_C PF01872.17 GAN08904.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Roc PF08477.13 GAN08904.1 - 0.21 11.8 1.1 6 7.1 0.0 2.9 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PMT PF02366.18 GAN08905.1 - 5.9e-86 288.0 19.9 5.9e-86 288.0 19.9 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAN08905.1 - 2.8e-61 206.6 17.0 2.8e-61 206.6 17.0 3.5 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAN08905.1 - 1.9e-33 115.9 1.1 3.2e-33 115.1 1.1 1.2 1 0 0 1 1 1 1 MIR domain Cation_efflux PF01545.21 GAN08906.1 - 6.3e-52 176.2 14.3 7.8e-52 175.9 14.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 GAN08906.1 - 0.00013 22.0 0.8 0.0026 17.7 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5134) CD20 PF04103.15 GAN08906.1 - 0.013 15.6 2.2 0.013 15.6 2.2 3.2 2 1 2 5 5 5 0 CD20-like family TMEM141 PF15110.6 GAN08906.1 - 0.024 15.2 0.8 0.074 13.6 0.2 2.1 2 1 0 2 2 2 0 TMEM141 protein family Metal_resist PF13801.6 GAN08906.1 - 0.074 13.2 0.2 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Heavy-metal resistance ETRAMP PF09716.10 GAN08906.1 - 0.092 12.8 4.5 0.13 12.3 0.1 3.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2796 PF10986.8 GAN08906.1 - 1 9.3 16.2 0.034 14.1 10.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Sigma_reg_N PF13800.6 GAN08906.1 - 8 6.8 0.0 8 6.8 0.0 3.5 3 2 1 4 4 4 0 Sigma factor regulator N-terminal FGGY_N PF00370.21 GAN08907.1 - 2.2e-70 237.0 0.0 3e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAN08907.1 - 7.8e-68 228.1 0.4 1.4e-67 227.3 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 GAN08907.1 - 0.073 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family SBDS PF01172.18 GAN08908.1 - 3.2e-19 68.8 0.1 3.6e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FF PF01846.19 GAN08909.1 - 3.7e-30 103.9 14.5 6.7e-13 48.6 2.3 3.6 3 0 0 3 3 3 3 FF domain WW PF00397.26 GAN08909.1 - 1.3e-14 54.0 9.0 1.4e-09 37.8 2.2 2.7 2 0 0 2 2 2 2 WW domain SNF2_N PF00176.23 GAN08910.1 - 3.2e-71 239.9 2.1 3.2e-71 239.9 2.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN08910.1 - 7.7e-23 81.0 0.2 4.3e-20 72.1 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 GAN08910.1 - 4.1e-21 74.9 1.3 1.5e-20 73.0 1.3 2.1 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 GAN08910.1 - 2.3e-18 66.3 11.6 2.3e-18 66.3 11.6 2.7 2 0 0 2 2 2 1 HSA SnAC PF14619.6 GAN08910.1 - 4.4e-15 56.1 1.1 4.4e-15 56.1 1.1 4.0 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 GAN08910.1 - 9.9e-12 44.4 7.0 3.5e-11 42.6 7.0 2.0 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 GAN08910.1 - 1.3e-10 41.6 0.1 3.5e-09 36.9 0.1 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHU_C PF13585.6 GAN08910.1 - 0.1 12.6 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Ribosomal_L1 PF00687.21 GAN08911.1 - 1.9e-37 129.0 2.7 4.3e-32 111.5 1.0 2.3 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family Metallophos PF00149.28 GAN08911.1 - 7.4e-37 127.8 0.4 1.3e-36 127.0 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN08911.1 - 0.00039 20.8 0.2 0.0011 19.4 0.2 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Dicer_dimer PF03368.14 GAN08911.1 - 0.066 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Dicer dimerisation domain RAMP4 PF06624.12 GAN08912.1 - 1.1e-06 28.6 0.9 1.4e-06 28.3 0.9 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 TMEM132D_C PF15706.5 GAN08912.1 - 0.033 13.9 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Dynamin_N PF00350.23 GAN08916.1 - 3.8e-06 27.0 3.7 1.1e-05 25.5 0.1 2.6 2 0 0 2 2 2 1 Dynamin family CCDC-167 PF15188.6 GAN08916.1 - 7.9 6.9 10.8 0.71 10.2 2.5 3.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 zf-RVT PF13966.6 GAN08918.1 - 2.8e-08 34.4 0.1 4.7e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase SH3_9 PF14604.6 GAN08919.1 - 1.7e-10 40.6 0.0 2.6e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN08919.1 - 4.2e-06 26.3 0.0 7.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Shisa PF13908.6 GAN08919.1 - 0.00074 19.8 1.9 0.00074 19.8 1.9 3.9 1 1 3 4 4 3 1 Wnt and FGF inhibitory regulator SH3_2 PF07653.17 GAN08919.1 - 0.0009 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_gE PF02480.16 GAN08919.1 - 0.001 18.0 0.1 0.001 18.0 0.1 2.2 2 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E DAG1 PF05454.11 GAN08919.1 - 0.0026 17.2 0.1 0.0048 16.3 0.1 1.6 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) RIFIN PF02009.16 GAN08919.1 - 0.0029 17.5 6.8 0.0029 17.5 6.8 2.8 2 1 0 2 2 2 1 Rifin VSP PF03302.13 GAN08919.1 - 0.0043 16.0 3.6 0.0093 14.9 3.6 1.5 1 0 0 1 1 1 1 Giardia variant-specific surface protein EphA2_TM PF14575.6 GAN08919.1 - 0.009 16.9 0.5 0.047 14.6 0.0 2.5 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 GAN08919.1 - 0.041 12.7 0.2 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SNARE_assoc PF09335.11 GAN08919.1 - 0.055 14.0 0.3 0.12 12.8 0.0 1.7 2 0 0 2 2 1 0 SNARE associated Golgi protein Chordopox_A13L PF05961.11 GAN08919.1 - 0.089 13.0 0.0 0.089 13.0 0.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus A13L protein DUF4064 PF13273.6 GAN08919.1 - 0.11 12.8 0.4 0.11 12.8 0.4 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4381 PF14316.6 GAN08919.1 - 0.64 10.3 0.0 0.64 10.3 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4381) DUF202 PF02656.15 GAN08919.1 - 1.6 9.3 6.2 13 6.3 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Orf78 PF06024.12 GAN08919.1 - 3.7 7.9 0.0 3.7 7.9 0.0 3.7 4 1 0 4 4 4 0 Orf78 (ac78) Miga PF10265.9 GAN08919.1 - 4.1 6.3 14.5 1.2 8.0 1.0 2.2 2 0 0 2 2 2 0 Mitoguardin ATP-synt_D PF01813.17 GAN08920.1 - 0.17 11.7 0.2 1 9.2 0.1 1.9 1 1 1 2 2 2 0 ATP synthase subunit D INO80_Ies4 PF08193.11 GAN08920.1 - 0.45 10.5 6.9 0.66 9.9 6.9 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 CBF PF03914.17 GAN08921.1 - 4e-53 179.9 0.3 4e-53 179.9 0.3 3.7 3 0 0 3 3 3 2 CBF/Mak21 family Cnd1 PF12717.7 GAN08921.1 - 6e-05 23.1 2.7 6e-05 23.1 2.7 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 SDA1 PF05285.12 GAN08921.1 - 5.2 6.4 81.3 0.065 12.7 22.0 4.4 4 0 0 4 4 4 0 SDA1 Ion_trans PF00520.31 GAN08922.1 - 1.8e-144 479.3 102.4 1.7e-46 158.5 17.1 4.1 4 0 0 4 4 4 4 Ion transport protein CIF PF16374.5 GAN08922.1 - 0.049 13.7 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Cycle inhibiting factor (CIF) DUF5096 PF17019.5 GAN08922.1 - 0.05 13.4 0.3 7 6.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5096) DUF3484 PF11983.8 GAN08922.1 - 6.9 7.9 6.8 3.5 8.8 0.1 3.0 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch CPSase_L_D2 PF02786.17 GAN08923.1 - 4e-112 372.8 0.2 1.1e-83 279.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAN08923.1 - 1.1e-48 164.3 0.0 2.9e-48 162.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAN08923.1 - 6e-45 153.4 0.0 2.6e-44 151.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 GAN08923.1 - 8.7e-45 152.4 0.0 1.9e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 GAN08923.1 - 4e-40 136.9 0.0 1.3e-39 135.3 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 GAN08923.1 - 4.8e-34 117.7 0.1 3e-33 115.1 0.1 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 GAN08923.1 - 2.2e-18 66.2 0.0 1.4e-17 63.6 0.0 2.6 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 GAN08923.1 - 5.3e-15 55.5 1.7 5e-07 29.5 0.1 2.9 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAN08923.1 - 3.1e-13 49.7 0.1 8e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 GAN08923.1 - 1.2e-09 37.9 0.0 0.00021 21.1 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 GAN08923.1 - 0.00018 21.3 0.4 0.022 14.5 0.4 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 GAN08923.1 - 0.00068 19.7 0.3 0.48 10.5 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 GAN08923.1 - 0.00077 19.3 0.4 1.8 8.3 0.0 4.8 6 0 0 6 6 6 1 DJ-1/PfpI family GSH-S_ATP PF02955.16 GAN08923.1 - 0.045 13.1 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Biotin_carb_N PF00289.22 GAN08923.1 - 0.16 12.5 1.5 1.4 9.5 0.0 3.4 4 0 0 4 4 4 0 Biotin carboxylase, N-terminal domain HSP70 PF00012.20 GAN08925.1 - 3e-264 877.8 13.1 3.4e-264 877.6 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN08925.1 - 3.8e-15 55.5 4.3 8.4e-13 47.8 1.1 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GAN08925.1 - 0.0009 19.0 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAN08925.1 - 0.044 14.2 10.9 1.6 9.2 0.2 4.2 3 2 0 3 3 3 0 Cell division protein FtsA SAM_DrpA PF18255.1 GAN08925.1 - 0.052 13.8 0.1 17 5.7 0.0 2.5 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain Drf_FH3 PF06367.16 GAN08925.1 - 0.076 12.6 1.8 0.14 11.8 1.8 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain Phlebovirus_NSM PF07246.11 GAN08925.1 - 0.48 9.8 6.5 0.5 9.7 5.3 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GCN5L1 PF06320.13 GAN08926.1 - 3.2e-36 124.0 11.2 9e-25 87.1 8.0 2.0 2 0 0 2 2 2 2 GCN5-like protein 1 (GCN5L1) Pox_polyA_pol_C PF12629.7 GAN08926.1 - 0.0019 18.1 0.4 0.0024 17.7 0.4 1.2 1 0 0 1 1 1 1 Poxvirus poly(A) polymerase C-terminal domain Phycobilisome PF00502.19 GAN08926.1 - 0.03 14.2 0.6 0.042 13.8 0.6 1.4 1 1 0 1 1 1 0 Phycobilisome protein Atg14 PF10186.9 GAN08926.1 - 0.04 13.0 3.4 0.04 13.0 3.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMP-TENI PF02581.17 GAN08926.1 - 0.041 13.2 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase DUF2014 PF09427.10 GAN08926.1 - 0.15 11.4 3.8 0.33 10.3 2.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2014) NusB PF01029.18 GAN08926.1 - 0.16 12.2 4.0 0.24 11.7 4.0 1.2 1 0 0 1 1 1 0 NusB family DUF5471 PF17565.2 GAN08926.1 - 0.2 11.9 4.7 0.25 11.6 0.3 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5471) Tweety PF04906.13 GAN08926.1 - 0.69 8.5 3.4 0.71 8.5 3.4 1.2 1 0 0 1 1 1 0 Tweety Prominin PF05478.11 GAN08926.1 - 0.78 7.6 6.1 0.82 7.5 6.1 1.1 1 0 0 1 1 1 0 Prominin DUF883 PF05957.13 GAN08926.1 - 1.3 9.7 4.6 6.4 7.5 3.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LMBR1 PF04791.16 GAN08926.1 - 1.6 7.6 4.9 1.5 7.6 4.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Synaptobrevin PF00957.21 GAN08926.1 - 1.6 8.6 6.7 0.24 11.2 2.5 1.8 2 1 0 2 2 2 0 Synaptobrevin DUF948 PF06103.11 GAN08926.1 - 9.8 6.5 8.0 1.2e+02 3.0 7.4 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) LAG1-DNAbind PF09271.11 GAN08927.1 - 1.5e-44 152.3 2.3 1.5e-44 152.3 2.3 4.5 3 1 0 3 3 3 1 LAG1, DNA binding BTD PF09270.10 GAN08927.1 - 7e-23 81.6 0.1 9.3e-17 61.7 0.0 3.7 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 GAN08927.1 - 0.00041 20.4 0.1 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain MFS_1 PF07690.16 GAN08928.1 - 5e-47 160.5 52.1 2.9e-46 158.0 49.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN08928.1 - 1e-15 57.6 14.1 1e-15 57.6 14.1 3.0 2 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAN08928.1 - 4.4e-09 35.3 22.3 1.4e-08 33.7 22.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trehalose_PPase PF02358.16 GAN08929.1 - 8.9e-65 218.1 0.0 1.4e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.21 GAN08929.1 - 0.0086 14.8 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 20 Hydrolase_3 PF08282.12 GAN08929.1 - 0.0099 15.6 0.4 0.83 9.3 0.1 2.6 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Glyco_hydro_18 PF00704.28 GAN08930.1 - 3.6e-20 72.9 3.1 3.6e-20 72.9 3.1 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 GAN08930.1 - 1.1 10.0 15.5 0.095 13.3 4.3 3.3 2 0 0 2 2 2 0 Carbohydrate binding domain MIF4G PF02854.19 GAN08931.1 - 1.2e-27 96.9 2.9 1.2e-27 96.9 2.9 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 GAN08931.1 - 8.9e-24 83.7 0.4 3.5e-23 81.8 0.1 2.3 2 0 0 2 2 2 1 MA3 domain GRA6 PF05084.13 GAN08931.1 - 0.58 10.1 5.1 61 3.5 6.4 2.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Sugar_tr PF00083.24 GAN08932.1 - 6.8e-84 282.3 18.1 3.2e-83 280.1 18.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN08932.1 - 1.9e-22 79.7 31.7 1.9e-22 79.7 31.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAN08932.1 - 3.1e-06 26.8 7.0 3.1e-06 26.8 7.0 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 GAN08932.1 - 0.016 13.6 14.2 0.0059 15.1 5.7 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MitoNEET_N PF10660.9 GAN08932.1 - 0.047 13.7 0.0 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus TNFR_16_TM PF18422.1 GAN08932.1 - 1.3 9.0 3.6 0.94 9.5 0.2 2.5 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Roughex PF06020.11 GAN08933.1 - 0.048 12.8 4.5 0.14 11.2 4.5 1.7 1 0 0 1 1 1 0 Drosophila roughex protein Sigma70_ner PF04546.13 GAN08934.1 - 0.0019 18.1 1.2 0.0031 17.4 1.2 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region BSP_II PF05432.11 GAN08934.1 - 0.0027 17.5 6.1 0.0035 17.1 6.1 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 GAN08934.1 - 0.03 12.6 1.1 0.03 12.6 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 GAN08934.1 - 0.057 13.9 4.4 0.08 13.4 4.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 GAN08934.1 - 0.094 10.9 7.3 0.12 10.6 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 GAN08934.1 - 0.69 9.3 9.7 0.93 8.8 9.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 GAN08934.1 - 0.84 8.7 7.7 1.1 8.4 7.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sporozoite_P67 PF05642.11 GAN08934.1 - 2 6.4 4.2 2.6 6.0 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 GAN08934.1 - 2.5 7.4 11.9 3.4 7.0 11.9 1.1 1 0 0 1 1 1 0 SDA1 Kin17_mid PF10357.9 GAN08934.1 - 3.3 7.6 7.3 0.6 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein DUF2457 PF10446.9 GAN08934.1 - 7.4 5.6 17.5 10 5.1 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 GAN08934.1 - 9.6 5.9 8.8 19 4.9 8.8 1.5 1 0 0 1 1 1 0 FAM176 family PIGA PF08288.12 GAN08935.1 - 4.8e-45 152.1 0.5 1.2e-44 150.8 0.5 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 GAN08935.1 - 1.7e-29 103.0 1.0 3.4e-29 102.0 0.4 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 GAN08935.1 - 1.7e-24 86.3 0.0 3.1e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN08935.1 - 5.2e-20 72.2 0.1 1.1e-19 71.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAN08935.1 - 3.9e-11 43.6 0.0 6.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 GAN08935.1 - 1.2e-06 28.6 0.2 2.5e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like CFTR_R PF14396.6 GAN08935.1 - 0.029 13.9 0.3 0.22 11.1 0.3 2.1 2 0 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain CTP_transf_like PF01467.26 GAN08936.1 - 5.1e-31 107.8 0.0 8.7e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 GAN08936.1 - 0.021 15.0 0.0 0.084 13.1 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5639) DUF5499 PF17603.2 GAN08936.1 - 0.12 13.0 0.1 0.4 11.3 0.1 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5499) RhoGAP PF00620.27 GAN08938.1 - 1.5e-35 122.2 0.0 2.6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Sugar_tr PF00083.24 GAN08939.1 - 1.2e-129 433.2 33.1 1.4e-129 433.0 33.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN08939.1 - 5.1e-23 81.6 49.0 6.7e-17 61.4 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PseudoU_synth_2 PF00849.22 GAN08940.1 - 1.7e-31 109.4 0.1 2.1e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase RNA_binding PF01877.17 GAN08940.1 - 0.082 13.2 0.2 0.45 10.8 0.2 2.0 1 1 0 1 1 1 0 RNA binding ACC_central PF08326.12 GAN08941.1 - 2.2e-250 832.9 3.3 2.8e-250 832.6 3.3 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 GAN08941.1 - 5e-176 586.2 0.0 6.8e-176 585.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAN08941.1 - 3.9e-54 183.3 0.0 7.9e-54 182.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAN08941.1 - 8.1e-29 100.4 0.1 2.1e-28 99.1 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN08941.1 - 3.1e-20 72.3 0.0 3.6e-19 68.9 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAN08941.1 - 1.6e-15 56.6 0.0 3.8e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 GAN08941.1 - 0.00027 21.0 0.0 0.00093 19.3 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAN08941.1 - 0.00092 19.0 0.0 0.0042 16.9 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.22 GAN08941.1 - 0.0014 18.2 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAN08941.1 - 0.034 13.7 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 GAN08941.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 GAN08941.1 - 0.063 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Ribosomal_L32e PF01655.18 GAN08942.1 - 0.079 13.4 0.0 0.092 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L32 zf-C2H2 PF00096.26 GAN08943.1 - 0.031 14.7 1.5 0.031 14.7 1.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type RskA PF10099.9 GAN08943.1 - 0.034 14.4 0.5 0.034 14.4 0.5 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2110 PF09883.9 GAN08943.1 - 0.055 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Endonuc_Holl PF10107.9 GAN08943.1 - 0.25 11.2 2.7 0.4 10.5 2.7 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase ESM4 PF15952.5 GAN08943.1 - 0.73 10.2 15.0 0.19 12.2 11.0 2.0 2 0 0 2 2 2 0 Enhancer of split M4 family NINJA_B PF16136.5 GAN08943.1 - 1 9.7 7.8 0.36 11.2 3.3 2.4 2 0 0 2 2 2 0 Putative nuclear localisation signal TFIIA PF03153.13 GAN08944.1 - 2.1 8.3 10.0 2.5 8.0 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GATA PF00320.27 GAN08945.1 - 5.2e-29 99.6 19.7 1.2e-14 53.6 7.3 2.5 2 0 0 2 2 2 2 GATA zinc finger Androgen_recep PF02166.16 GAN08945.1 - 0.0031 16.5 1.9 0.0031 16.5 1.9 3.5 3 1 1 4 4 4 1 Androgen receptor TF_Zn_Ribbon PF08271.12 GAN08945.1 - 0.0039 16.7 4.6 0.15 11.6 0.5 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding TDP43_N PF18694.1 GAN08945.1 - 0.025 14.4 0.2 0.091 12.6 0.1 1.9 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain OrfB_Zn_ribbon PF07282.11 GAN08945.1 - 0.034 14.1 0.4 0.034 14.1 0.4 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 GAN08945.1 - 0.12 12.6 7.3 0.2 11.8 0.7 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 GAN08945.1 - 0.17 12.0 5.6 0.78 9.9 0.7 2.9 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 GAN08945.1 - 1.9 8.4 7.2 3.4 7.6 1.0 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 CPSF100_C PF13299.6 GAN08945.1 - 4.3 7.5 8.6 2.8 8.1 0.6 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 GAN08945.1 - 6.4 6.4 10.1 1.5 8.5 1.9 2.4 2 0 0 2 2 2 0 FAM176 family zf-C3HC4_3 PF13920.6 GAN08947.1 - 4.2e-09 36.1 5.9 7.5e-09 35.3 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 GAN08947.1 - 1.1e-07 31.6 1.5 2.3e-07 30.5 1.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 GAN08947.1 - 5.1e-07 29.4 9.1 9.6e-07 28.6 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN08947.1 - 7.5e-07 29.1 9.7 1.7e-06 28.0 9.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAN08947.1 - 3e-06 27.1 10.0 5.1e-06 26.3 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAN08947.1 - 1e-05 25.3 10.7 2.1e-05 24.3 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN08947.1 - 2e-05 24.8 8.0 3.7e-05 24.0 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 GAN08947.1 - 3.8e-05 23.6 2.5 8e-05 22.6 2.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RanBP PF00641.18 GAN08947.1 - 7.5e-05 22.0 2.3 7.5e-05 22.0 2.3 1.7 2 0 0 2 2 1 1 Zn-finger in Ran binding protein and others zf-C3HC4_4 PF15227.6 GAN08947.1 - 0.0001 22.4 8.4 0.00026 21.1 8.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 GAN08947.1 - 0.00037 20.6 4.2 0.00037 20.6 4.2 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 GAN08947.1 - 0.0042 16.9 7.0 0.0077 16.1 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 GAN08947.1 - 0.019 14.7 1.7 0.045 13.6 1.7 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf-Nse PF11789.8 GAN08947.1 - 0.034 14.0 2.7 0.068 13.0 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LepA_C PF06421.12 GAN08947.1 - 0.084 13.0 0.2 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Vps36-NZF-N PF16988.5 GAN08947.1 - 0.11 11.9 1.6 0.26 10.7 1.6 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc-ribbons_6 PF07191.12 GAN08947.1 - 0.14 12.2 4.6 0.33 11.0 4.6 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-P11 PF03854.14 GAN08947.1 - 0.24 11.1 2.9 0.5 10.1 2.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger Ribosomal_L34e PF01199.18 GAN08947.1 - 0.83 10.0 4.9 0.14 12.5 0.6 1.9 2 0 0 2 2 1 0 Ribosomal protein L34e WBS_methylT PF12589.8 GAN08947.1 - 6.8 7.5 10.4 0.41 11.4 2.7 2.8 1 1 1 2 2 1 0 Methyltransferase involved in Williams-Beuren syndrome Abhydrolase_1 PF00561.20 GAN08948.1 - 6.3e-48 163.6 0.0 5.3e-46 157.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN08948.1 - 0.0011 18.3 0.0 0.092 12.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 GAN08948.1 - 0.0022 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 GAN08948.1 - 0.069 12.3 0.1 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Arrestin_C PF02752.22 GAN08949.1 - 4.9e-05 23.8 2.3 0.00015 22.2 2.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain zf-C2HC5 PF06221.13 GAN08950.1 - 2.3e-22 78.7 8.0 4.2e-22 77.9 8.0 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF2870 PF11069.8 GAN08950.1 - 0.46 10.9 0.0 0.46 10.9 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2870) HGTP_anticodon PF03129.20 GAN08951.1 - 1.3e-22 79.8 0.1 1.1e-21 76.8 0.0 2.6 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAN08951.1 - 5.3e-09 36.3 0.1 2.8e-08 33.9 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) RRM_1 PF00076.22 GAN08952.1 - 1.1e-14 54.0 0.0 1.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GAN08952.1 - 1.7e-08 34.2 4.8 3.2e-08 33.3 4.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 GAN08952.1 - 0.13 12.3 1.3 0.26 11.3 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_25 PF13649.6 GAN08953.1 - 2.1e-16 60.4 0.0 4.4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN08953.1 - 1.7e-12 47.5 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN08953.1 - 5.5e-12 46.2 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN08953.1 - 1.5e-10 41.0 0.0 1e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN08953.1 - 1.5e-09 37.6 0.0 1.1e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAN08953.1 - 6.3e-09 36.5 0.0 1.3e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN08953.1 - 1.6e-06 27.7 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAN08953.1 - 0.00043 20.2 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 GAN08953.1 - 0.0028 17.2 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 GAN08953.1 - 0.024 14.8 0.0 0.096 12.8 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 GAN08953.1 - 0.036 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CheR PF01739.18 GAN08953.1 - 0.043 13.3 0.0 2 7.9 0.0 2.5 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 GAN08953.1 - 0.045 12.7 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) GST_C_3 PF14497.6 GAN08955.1 - 5.1e-14 52.3 0.1 1e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN08955.1 - 0.00071 19.7 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN08955.1 - 0.0031 17.5 0.1 0.0073 16.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 GAN08956.1 - 1.7e-55 188.2 0.3 3.3e-55 187.3 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN08956.1 - 1.2e-41 142.7 0.3 1.9e-41 142.1 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 GAN08956.1 - 0.00013 22.1 0.1 0.0003 21.0 0.1 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 GAN08956.1 - 0.021 13.6 0.3 0.048 12.4 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase GH114_assoc PF14741.6 GAN08956.1 - 0.031 14.5 0.5 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain Gag_p24 PF00607.20 GAN08956.1 - 0.077 12.9 0.3 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Tropomyosin_1 PF12718.7 GAN08956.1 - 0.088 13.0 7.4 0.2 11.8 7.4 1.6 1 0 0 1 1 1 0 Tropomyosin like Rcd1 PF04078.13 GAN08957.1 - 7.4e-126 418.7 2.7 9.8e-126 418.3 2.7 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Spt20 PF12090.8 GAN08957.1 - 1.2 8.6 8.7 2.4 7.7 8.7 1.4 1 0 0 1 1 1 0 Spt20 family AhpC-TSA PF00578.21 GAN08958.1 - 1.5e-25 89.5 0.0 8.1e-25 87.1 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAN08958.1 - 1.6e-13 50.6 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 GAN08958.1 - 0.0028 17.8 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Cys_Met_Meta_PP PF01053.20 GAN08959.1 - 3.5e-157 522.8 0.1 4e-157 522.6 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAN08959.1 - 3.1e-07 29.7 0.2 2.7e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAN08959.1 - 4e-05 22.9 0.2 8.4e-05 21.9 0.2 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAN08959.1 - 6.6e-05 22.4 0.4 0.0002 20.8 0.1 1.8 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAN08959.1 - 0.0062 15.9 0.4 0.022 14.1 0.4 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Colicin_D PF11429.8 GAN08959.1 - 0.15 12.5 0.2 0.56 10.7 0.2 2.0 1 0 0 1 1 1 0 Colicin D Ribosomal_L26 PF16906.5 GAN08960.1 - 4.1e-36 123.3 3.5 5.3e-36 122.9 3.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAN08960.1 - 1.5e-10 40.6 3.8 3.8e-10 39.4 3.8 1.7 1 0 0 1 1 1 1 KOW motif DUF1442 PF07279.11 GAN08960.1 - 0.074 12.4 1.3 0.096 12.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) ASF1_hist_chap PF04729.13 GAN08961.1 - 4.4e-54 182.6 0.2 5.7e-54 182.2 0.2 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone NUP214 PF16755.5 GAN08962.1 - 6.4e-18 65.1 0.0 4.5e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 GAN08962.1 - 0.0037 17.5 0.0 4.7 7.6 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3712 PF12505.8 GAN08963.1 - 7.7e-25 87.6 14.0 3.9e-16 59.4 4.1 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAN08963.1 - 2.7e-05 24.6 1.6 8 7.1 0.0 4.9 4 1 0 4 4 4 2 Late embryogenesis abundant protein DUF3712 PF12505.8 GAN08964.1 - 1.6e-32 112.4 7.8 4.6e-20 72.2 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAN08964.1 - 0.024 15.2 0.9 23 5.6 0.0 3.5 4 1 0 4 4 4 0 Late embryogenesis abundant protein Sigma_reg_N PF13800.6 GAN08964.1 - 0.066 13.5 0.4 0.14 12.4 0.4 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF1356 PF07092.12 GAN08964.1 - 0.07 12.4 1.0 0.68 9.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Vac7 PF12751.7 GAN08965.1 - 3.8e-14 52.9 15.7 9.9e-12 45.0 15.7 3.1 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 adh_short_C2 PF13561.6 GAN08965.1 - 9.6e-11 41.7 0.1 2.3e-10 40.4 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN08965.1 - 3e-09 36.6 0.5 1.4e-08 34.4 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 GAN08965.1 - 0.0003 20.3 0.1 0.00094 18.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAN08965.1 - 0.1 11.7 0.3 0.79 8.8 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Glyco_tranf_2_3 PF13641.6 GAN08966.1 - 0.00098 19.1 0.4 0.13 12.1 0.2 3.0 3 1 1 4 4 4 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAN08966.1 - 0.023 14.5 0.1 0.93 9.3 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 STELLO PF03385.17 GAN08966.1 - 0.034 12.9 0.1 0.063 12.1 0.1 1.3 1 0 0 1 1 1 0 STELLO glycosyltransferases MPM1 PF17234.2 GAN08967.1 - 0.093 13.0 0.9 0.13 12.5 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 UPF0121 PF03661.13 GAN08968.1 - 3.2e-36 125.0 9.8 4.1e-36 124.6 9.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) KleE PF17394.2 GAN08968.1 - 0.07 13.4 2.4 0.51 10.6 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized KleE stable inheritance protein WH2 PF02205.20 GAN08969.1 - 7e-07 28.9 2.5 1.1e-06 28.2 1.6 1.9 2 0 0 2 2 2 1 WH2 motif Cyto_heme_lyase PF01265.17 GAN08970.1 - 5.8e-72 242.7 13.9 4.5e-71 239.8 13.9 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF2854 PF11016.8 GAN08970.1 - 0.034 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) BPL_LplA_LipB PF03099.19 GAN08971.1 - 1.3e-09 38.0 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SAP PF02037.27 GAN08972.1 - 9.3e-12 44.4 0.2 1.4e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 SAP domain Slu7 PF11708.8 GAN08973.1 - 1e-85 287.8 21.9 3.3e-85 286.1 15.3 2.3 1 1 1 2 2 2 2 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 GAN08973.1 - 0.21 11.3 0.7 0.38 10.5 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle CaM_binding PF07839.11 GAN08973.1 - 0.25 12.1 0.2 0.25 12.1 0.2 3.2 3 1 1 4 4 4 0 Plant calmodulin-binding domain Exo_endo_phos PF03372.23 GAN08975.1 - 1.2e-11 44.5 0.0 1.8e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ThrE PF06738.12 GAN08976.1 - 1.6e-53 181.6 13.6 1.2e-48 165.6 1.3 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAN08976.1 - 0.032 14.4 27.1 0.035 14.3 9.6 2.4 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE B-block_TFIIIC PF04182.12 GAN08977.1 - 1.7e-14 53.7 0.6 5.7e-14 52.0 0.6 2.0 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 GAN08977.1 - 5.6e-06 25.8 0.1 9e-05 22.0 0.0 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 GAN08977.1 - 0.00036 20.4 0.0 0.0013 18.6 0.0 2.0 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 GAN08977.1 - 0.0018 18.1 0.0 0.0068 16.3 0.0 2.1 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 GAN08977.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 HTH domain RPA_C PF08784.11 GAN08977.1 - 0.088 13.5 0.3 1.1 10.0 0.1 2.8 2 0 0 2 2 2 0 Replication protein A C terminal DUF2513 PF10711.9 GAN08977.1 - 1 9.7 3.8 1 9.7 0.1 2.9 3 0 0 3 3 3 0 Hypothetical protein (DUF2513) polyprenyl_synt PF00348.17 GAN08978.1 - 5.9e-46 156.6 0.0 9.4e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 GAN08978.1 - 0.0021 17.6 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase HEPPP_synt_1 PF07307.11 GAN08978.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Myb_DNA-binding PF00249.31 GAN08979.1 - 3.9e-05 23.8 0.1 7.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRAM_LAG1_CLN8 PF03798.16 GAN08980.1 - 1.1e-35 123.2 28.9 2.8e-35 121.9 28.6 1.7 1 1 1 2 2 2 1 TLC domain zf-C2H2 PF00096.26 GAN08981.1 - 8e-09 35.5 65.3 0.0004 20.7 1.3 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN08981.1 - 5.5e-08 32.9 15.5 5.9e-06 26.5 3.7 6.6 7 0 0 7 7 7 2 Zinc-finger double domain SUIM_assoc PF16619.5 GAN08981.1 - 0.0031 17.5 6.2 0.0031 17.5 6.2 8.5 4 3 2 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 CDK2AP PF09806.9 GAN08981.1 - 0.02 15.0 6.9 0.02 15.0 6.9 5.0 5 0 0 5 5 5 0 Cyclin-dependent kinase 2-associated protein FOXP-CC PF16159.5 GAN08981.1 - 0.72 10.5 0.1 0.68 10.6 5.6 7.7 7 1 1 8 8 8 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 GAN08981.1 - 4.8 7.3 13.6 3.3 7.8 3.4 3.2 2 1 0 2 2 2 0 Aberrant zinc-finger GSH_synth_ATP PF03917.17 GAN08982.1 - 3.5e-138 460.5 0.0 4e-138 460.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAN08982.1 - 1.2e-35 122.0 0.0 2.3e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DDE_3 PF13358.6 GAN08983.1 - 0.00029 20.6 0.3 0.00042 20.1 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Tubulin PF00091.25 GAN08984.1 - 1.1e-61 208.5 0.0 1.8e-61 207.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAN08984.1 - 3.9e-40 136.9 0.0 5.9e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 GAN08984.1 - 0.038 13.2 0.0 0.08 12.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 GAN08984.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Pex2_Pex12 PF04757.14 GAN08985.1 - 3.5e-50 170.7 7.5 4.2e-50 170.4 7.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 GAN08985.1 - 2.2e-06 27.4 1.2 3.5e-06 26.8 1.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN08985.1 - 9.2e-05 22.7 1.9 0.00015 22.0 1.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN08985.1 - 0.00044 20.0 1.9 0.0008 19.2 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN08985.1 - 0.0057 16.5 1.5 0.0096 15.8 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAN08985.1 - 0.022 14.9 5.4 0.042 14.0 5.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 GAN08985.1 - 0.049 13.7 0.9 0.083 12.9 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 GAN08985.1 - 0.083 12.9 5.2 0.17 11.9 5.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Adaptin_N PF01602.20 GAN08986.1 - 1.7e-114 383.3 1.4 2.3e-114 382.9 1.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAN08986.1 - 6.2e-57 192.0 0.6 1.5e-56 190.7 0.6 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GAN08986.1 - 4.4e-32 110.6 0.0 1e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAN08986.1 - 3.6e-21 75.3 0.0 2.1e-09 37.6 0.0 5.5 5 1 0 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAN08986.1 - 5.8e-08 32.9 6.9 0.0078 16.3 0.0 4.8 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAN08986.1 - 0.013 15.7 6.3 18 5.9 0.0 6.1 7 0 0 7 7 7 0 HEAT repeat Rad60-SLD_2 PF13881.6 GAN08986.1 - 0.03 14.4 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HEAT_PBS PF03130.16 GAN08986.1 - 0.063 14.0 9.8 1.4 9.8 0.0 5.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat ThiF PF00899.21 GAN08987.1 - 6.3e-41 140.3 0.0 1e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 GAN08987.1 - 1.4e-05 25.4 0.9 0.00018 21.8 0.8 2.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 GAN08987.1 - 0.005 16.1 0.1 0.0089 15.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 GAN08987.1 - 0.021 14.9 0.5 0.053 13.6 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAN08987.1 - 0.036 13.7 0.1 0.076 12.6 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 GAN08987.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAN08987.1 - 0.066 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 GAN08987.1 - 0.071 13.6 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 GAN08987.1 - 0.11 12.1 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase CagA PF03507.13 GAN08987.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 CagA exotoxin MFS_1 PF07690.16 GAN08988.1 - 4.3e-41 141.0 23.5 4.3e-41 141.0 23.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAN08988.1 - 9.9e-05 21.8 3.3 9.9e-05 21.8 3.3 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB OAD_gamma PF04277.13 GAN08988.1 - 2.7 8.6 6.9 2.1 9.0 0.5 3.5 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF3185 PF11381.8 GAN08988.1 - 9.2 6.4 8.6 34 4.5 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) CDC45 PF02724.14 GAN08991.1 - 0.00095 17.6 9.9 0.00095 17.6 9.9 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GAN08991.1 - 0.0022 17.5 14.8 0.0022 17.5 14.8 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GAN08991.1 - 0.0051 16.2 10.6 0.0063 15.9 10.6 1.1 1 0 0 1 1 1 1 BUD22 Sporozoite_P67 PF05642.11 GAN08991.1 - 0.019 13.1 3.1 0.018 13.2 3.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Chordopox_L2 PF05803.12 GAN08991.1 - 0.069 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus L2 protein SAPS PF04499.15 GAN08991.1 - 0.48 9.2 4.9 0.48 9.2 4.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 GAN08991.1 - 0.55 8.7 14.4 0.58 8.6 14.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GAN08991.1 - 1.3 7.2 26.3 1.6 6.9 26.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAN08991.1 - 4.3 5.3 35.1 6.1 4.8 35.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 GAN08991.1 - 6.4 6.8 25.1 8.9 6.3 25.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SecY PF00344.20 GAN08993.1 - 3.7e-58 197.2 14.5 4.4e-58 196.9 14.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAN08993.1 - 3.6e-14 52.3 0.4 2.2e-13 49.8 0.1 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p HSP70 PF00012.20 GAN08994.1 - 1.2e-258 859.3 6.0 1.4e-258 859.1 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN08994.1 - 7.6e-16 57.8 0.2 9.9e-15 54.2 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 GAN08994.1 - 0.013 14.8 0.1 0.029 13.6 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 GAN08994.1 - 0.023 14.4 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 GAN08994.1 - 0.033 13.4 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 StbA protein DUF3849 PF12960.7 GAN08994.1 - 0.14 12.1 0.5 0.29 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) SWI-SNF_Ssr4 PF08549.10 GAN08994.1 - 1.8 7.1 5.3 6.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) SDA1 PF05285.12 GAN08995.1 - 0.0018 17.8 6.1 0.002 17.7 6.1 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAN08995.1 - 0.004 15.5 6.5 0.004 15.4 6.5 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GAN08995.1 - 0.0061 14.9 3.7 0.0059 15.0 3.7 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 GAN08995.1 - 0.0068 15.8 6.8 0.0091 15.4 6.8 1.2 1 0 0 1 1 1 1 BUD22 GCIP PF13324.6 GAN08995.1 - 0.042 13.5 2.8 0.057 13.0 2.8 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GAN08995.1 - 0.079 11.1 15.4 0.1 10.7 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAN08995.1 - 0.11 11.0 5.1 0.13 10.8 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PGA2 PF07543.12 GAN08995.1 - 0.13 12.3 3.6 0.28 11.2 3.6 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 IFT57 PF10498.9 GAN08995.1 - 0.45 9.4 8.2 0.66 8.9 8.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Cwf_Cwc_15 PF04889.12 GAN08995.1 - 0.47 10.1 12.1 0.68 9.6 12.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 GAN08995.1 - 0.54 9.4 18.5 0.88 8.6 18.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.10 GAN08995.1 - 0.62 10.4 4.9 1.1 9.5 4.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Myc_N PF01056.18 GAN08995.1 - 0.66 9.8 9.2 0.12 12.2 4.9 1.7 1 1 1 2 2 2 0 Myc amino-terminal region FAM176 PF14851.6 GAN08995.1 - 0.71 9.5 5.3 1.3 8.6 5.3 1.5 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 GAN08995.1 - 0.78 9.8 7.2 1.2 9.2 7.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 GAN08995.1 - 1 8.7 11.6 1.4 8.3 11.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 GAN08995.1 - 1.4 8.1 14.8 1.9 7.7 14.8 1.1 1 0 0 1 1 1 0 NOA36 protein TT_ORF2 PF02957.15 GAN08995.1 - 3.1 8.7 11.7 2.6 9.0 9.4 1.9 2 0 0 2 2 2 0 TT viral ORF2 Pox_Ag35 PF03286.14 GAN08995.1 - 9.4 6.0 14.3 0.66 9.7 9.0 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sulfate_transp PF00916.20 GAN08997.1 - 4.2e-111 371.4 20.1 5.4e-111 371.0 20.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN08997.1 - 8.6e-12 44.7 0.0 2.1e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN08997.1 - 8.1e-05 23.0 2.5 8.1e-05 23.0 2.5 3.2 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 GAN08997.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 STAS domain CorA PF01544.18 GAN08998.1 - 2e-47 162.0 6.4 2.3e-29 102.7 0.7 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Nup84_Nup100 PF04121.13 GAN08999.1 - 9.9e-55 185.9 17.2 9.9e-55 185.9 17.2 1.5 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF3644 PF12358.8 GAN08999.1 - 0.0091 16.5 0.6 3.4 8.2 0.1 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3644) Med11 PF10280.9 GAN08999.1 - 0.013 15.9 0.4 0.033 14.7 0.4 1.7 1 0 0 1 1 1 0 Mediator complex protein FMN_red PF03358.15 GAN09000.1 - 0.00041 20.1 0.0 0.0037 17.0 0.0 2.1 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Pex2_Pex12 PF04757.14 GAN09001.1 - 2.8e-36 125.2 6.0 3.9e-36 124.7 6.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 GAN09001.1 - 0.0013 18.6 7.2 0.0022 17.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN09001.1 - 0.0043 16.9 3.1 0.018 14.9 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAN09001.1 - 0.0063 16.6 3.7 0.0063 16.6 3.7 1.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAN09001.1 - 0.023 14.7 6.8 0.048 13.7 6.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAN09001.1 - 0.06 13.2 5.7 0.27 11.1 5.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN09001.1 - 0.074 13.0 7.4 0.15 12.0 7.4 1.5 1 1 0 1 1 1 0 zinc-RING finger domain KRTDAP PF15200.6 GAN09001.1 - 0.085 12.7 0.3 0.2 11.4 0.3 1.7 1 0 0 1 1 1 0 Keratinocyte differentiation-associated zf-rbx1 PF12678.7 GAN09001.1 - 0.46 10.8 5.2 0.81 10.0 5.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAN09001.1 - 0.57 10.6 9.0 2.3 8.6 9.0 2.0 1 1 0 1 1 1 0 Ring finger domain TFIID-18kDa PF02269.16 GAN09002.1 - 4.1e-28 97.2 0.2 5.3e-28 96.9 0.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Aquarius_N PF16399.5 GAN09003.1 - 2e-296 985.3 16.2 2.9e-296 984.8 16.2 1.2 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 GAN09003.1 - 7.6e-29 101.3 0.0 3.4e-28 99.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 GAN09003.1 - 1.2e-28 100.1 0.0 2.8e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN09003.1 - 4.3e-09 36.9 0.0 1.4e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAN09003.1 - 3.6e-08 33.3 0.0 0.01 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 GAN09003.1 - 5.1e-05 23.3 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAN09003.1 - 0.0001 22.2 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 GAN09003.1 - 0.0033 17.2 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 GAN09003.1 - 0.0041 16.7 0.4 0.019 14.5 0.0 2.4 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 GAN09003.1 - 0.0053 16.0 0.2 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GAN09003.1 - 0.0072 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 GAN09003.1 - 0.014 15.7 0.0 0.067 13.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAN09003.1 - 0.021 15.2 0.0 0.068 13.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAN09003.1 - 0.029 13.9 0.0 0.095 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 GAN09003.1 - 0.039 13.3 1.6 33 3.7 0.0 4.2 4 0 0 4 4 4 0 UvrD-like helicase C-terminal domain RecA PF00154.21 GAN09003.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_16 PF13191.6 GAN09003.1 - 0.078 13.4 0.0 0.36 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GAN09003.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region HA2 PF04408.23 GAN09004.1 - 6.4e-19 68.2 0.2 6.4e-19 68.2 0.2 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAN09004.1 - 1.6e-12 47.7 0.0 5.5e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN09004.1 - 1.7e-06 27.9 0.5 1.5e-05 24.9 0.5 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAN09004.1 - 2e-05 24.8 0.1 9.8e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 GAN09004.1 - 6e-05 23.3 0.1 0.00014 22.2 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 GAN09004.1 - 0.00035 20.9 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAN09004.1 - 0.0023 17.0 0.0 0.0072 15.4 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 GAN09004.1 - 0.018 15.0 0.3 1.3 9.0 0.2 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 GAN09004.1 - 0.02 14.3 0.1 0.095 12.1 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein ATPase PF06745.13 GAN09004.1 - 0.045 13.1 0.0 0.41 9.9 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 GAN09004.1 - 0.11 12.6 0.1 0.56 10.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAN09004.1 - 0.11 13.0 2.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAN09004.1 - 0.48 10.0 3.0 13 5.3 0.0 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 GAN09004.1 - 3.2 8.3 5.2 1.1 9.8 0.1 2.7 3 1 0 3 3 3 0 ABC transporter Polysacc_deac_1 PF01522.21 GAN09005.1 - 2.1e-37 127.8 0.0 4e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN09005.1 - 8.9e-06 25.1 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 nec1 PF10379.9 GAN09005.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Virulence protein nec1 DUF2334 PF10096.9 GAN09005.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) TMEM154 PF15102.6 GAN09005.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.6 2 1 1 3 3 3 0 TMEM154 protein family Zip PF02535.22 GAN09005.1 - 0.58 9.3 3.9 1.1 8.4 3.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2796 PF10986.8 GAN09005.1 - 2.3 8.1 18.4 0.16 12.0 7.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) FAM176 PF14851.6 GAN09005.1 - 2.9 7.6 18.9 5.4 6.7 1.1 2.5 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 GAN09005.1 - 5.7 6.8 21.5 0.37 10.6 7.9 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF913 PF06025.12 GAN09005.1 - 8 5.3 10.2 0.046 12.7 1.6 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TRAM_LAG1_CLN8 PF03798.16 GAN09006.1 - 1.4e-36 126.1 23.1 1.4e-36 126.1 23.1 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAN09006.1 - 5.9e-16 57.9 0.2 5.9e-16 57.9 0.2 2.2 2 0 0 2 2 2 1 TRAM1-like protein GCS PF03074.16 GAN09007.1 - 2.6e-181 602.9 0.1 3.3e-181 602.5 0.1 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 GAN09007.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) F-box-like PF12937.7 GAN09008.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 GAN09008.1 - 0.015 15.3 2.0 22 5.4 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 GAN09008.1 - 0.028 14.8 0.1 22 5.7 0.0 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN09008.1 - 0.043 13.7 0.6 0.21 11.5 0.2 2.4 2 1 0 2 2 2 0 F-box domain EF-hand_13 PF17958.1 GAN09009.1 - 6.2e-22 77.2 0.0 2.2e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 GAN09009.1 - 2.8e-08 34.1 0.1 2.8e-08 34.1 0.1 3.7 4 2 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 GAN09009.1 - 0.082 12.8 0.9 3.4 7.6 0.3 3.6 4 0 0 4 4 4 0 EF-hand domain pair FAM176 PF14851.6 GAN09009.1 - 1.4 8.6 4.5 2.6 7.7 4.5 1.5 1 0 0 1 1 1 0 FAM176 family DUF755 PF05501.11 GAN09010.1 - 0.04 14.2 1.7 0.04 14.2 1.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF755) GalP_UDP_transf PF01087.22 GAN09011.1 - 6.5e-71 238.6 2.0 3.4e-70 236.2 0.8 2.3 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 GAN09011.1 - 1.6e-63 213.4 0.0 3e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 GAN09011.1 - 1.7e-05 25.3 0.0 4.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 GAN09011.1 - 0.00049 20.8 0.0 0.021 15.5 0.0 2.3 2 0 0 2 2 2 1 HIT domain DUF4931 PF16285.5 GAN09011.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) RGI1 PF10843.8 GAN09011.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Respiratory growth induced protein 1 WG_beta_rep PF14903.6 GAN09011.1 - 0.083 13.2 0.1 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 WG containing repeat DUF4921 PF16268.5 GAN09011.1 - 0.17 10.7 0.6 12 4.6 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4921) Fungal_trans PF04082.18 GAN09012.1 - 1.7e-20 73.2 0.3 5.4e-20 71.5 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4887 PF16228.5 GAN09013.1 - 0.11 12.6 4.9 0.14 12.4 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Mito_fiss_reg PF05308.11 GAN09013.1 - 0.12 12.5 3.6 0.13 12.4 3.6 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator KCH PF16944.5 GAN09015.1 - 5e-81 272.2 10.2 6.5e-81 271.8 10.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel zf-rbx1 PF12678.7 GAN09016.1 - 3.2e-13 49.7 3.9 8.5e-13 48.4 3.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAN09016.1 - 4.5e-10 39.7 3.9 4.5e-10 39.7 3.9 2.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAN09016.1 - 3e-08 33.4 3.5 1.4e-07 31.3 3.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN09016.1 - 1.1e-07 31.7 1.9 4.3e-07 29.9 1.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAN09016.1 - 7e-06 25.8 5.3 7e-06 25.8 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN09016.1 - 1.7e-05 24.6 6.9 0.00018 21.3 1.7 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN09016.1 - 9e-05 22.4 5.2 0.00065 19.6 5.7 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAN09016.1 - 0.00011 22.2 5.3 0.0007 19.6 5.3 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAN09016.1 - 0.00011 22.0 3.8 0.00028 20.7 1.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAN09016.1 - 0.0005 20.2 1.6 0.0016 18.6 1.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 GAN09016.1 - 0.00053 19.5 1.9 0.0013 18.3 1.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 GAN09016.1 - 0.00085 19.0 1.2 0.00085 19.0 1.2 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING-like PF08746.11 GAN09016.1 - 0.22 11.9 3.9 0.49 10.7 3.9 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 GAN09016.1 - 0.81 9.5 5.2 0.66 9.8 1.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GAN09016.1 - 1.1 9.4 6.7 0.4 10.9 2.9 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-3CxxC_2 PF17180.4 GAN09016.1 - 8.3 7.2 6.7 0.78 10.5 0.6 2.4 3 0 0 3 3 3 0 Zinc-binding domain Amino_oxidase PF01593.24 GAN09017.1 - 1.2e-59 202.8 0.0 1.5e-59 202.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAN09017.1 - 4.4e-10 39.6 0.2 1.5e-09 37.9 0.4 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN09017.1 - 1.5e-06 27.7 0.0 0.0057 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN09017.1 - 2.4e-05 23.8 0.6 0.0016 17.8 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN09017.1 - 0.00012 21.6 0.1 0.008 15.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 GAN09017.1 - 0.00025 20.7 1.3 0.0037 16.9 0.6 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAN09017.1 - 0.00031 20.1 1.8 0.00049 19.4 0.3 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAN09017.1 - 0.0021 17.4 0.1 0.0035 16.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAN09017.1 - 0.01 16.4 3.6 0.073 13.6 0.2 3.2 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAN09017.1 - 0.014 14.1 1.4 0.03 13.0 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 GAN09017.1 - 0.016 14.4 0.5 0.027 13.6 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Vac_ImportDeg PF09783.9 GAN09017.1 - 0.023 14.5 0.2 0.043 13.6 0.2 1.4 1 0 0 1 1 1 0 Vacuolar import and degradation protein ThiF PF00899.21 GAN09017.1 - 0.048 13.0 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 GAN09017.1 - 0.093 13.0 0.4 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 GAN09017.1 - 0.097 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAN09017.1 - 0.11 11.6 1.4 0.24 10.5 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 GAN09017.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase STE PF02200.16 GAN09018.1 - 1.7e-52 176.5 0.0 3.1e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 GAN09018.1 - 6.3e-08 32.7 15.7 0.00052 20.3 3.8 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN09018.1 - 0.011 16.6 14.8 0.19 12.6 3.3 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger Ogr_Delta PF04606.12 GAN09018.1 - 0.092 12.7 0.2 0.29 11.2 0.2 1.9 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Coatamer_beta_C PF07718.12 GAN09018.1 - 0.13 12.1 2.8 0.16 11.8 0.6 2.2 2 0 0 2 2 2 0 Coatomer beta C-terminal region Pkinase PF00069.25 GAN09019.1 - 1.8e-71 240.6 0.4 1.8e-71 240.6 0.4 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09019.1 - 1.6e-51 175.1 0.2 1.6e-51 175.1 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 GAN09019.1 - 6.2e-20 71.3 0.0 1.9e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 GAN09019.1 - 4e-10 40.1 1.5 5.1e-10 39.8 0.3 1.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 GAN09019.1 - 0.00022 20.7 3.0 0.00071 19.0 0.0 2.5 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 GAN09019.1 - 0.0028 16.7 2.8 0.0028 16.7 2.8 2.2 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAN09019.1 - 0.0058 15.5 19.6 0.072 11.9 19.6 2.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAN09019.1 - 0.014 15.4 0.1 0.82 9.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sec3-PIP2_bind PF15277.6 GAN09019.1 - 0.028 14.5 0.3 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Kdo PF06293.14 GAN09019.1 - 0.036 13.4 0.4 0.076 12.4 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_9 PF15410.6 GAN09019.1 - 0.08 13.3 5.5 0.95 9.9 0.1 4.0 4 1 0 4 4 4 0 Pleckstrin homology domain PH_11 PF15413.6 GAN09019.1 - 0.16 12.4 4.3 1.7 9.1 0.4 3.5 2 1 0 2 2 2 0 Pleckstrin homology domain zf-H2C2_2 PF13465.6 GAN09020.1 - 6.5e-08 32.7 17.6 0.00035 20.9 3.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAN09020.1 - 5.1e-07 29.8 26.1 1.8e-05 24.9 0.7 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN09020.1 - 8.1e-07 29.4 24.0 0.0088 16.8 0.6 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN09020.1 - 0.001 19.0 4.6 0.032 14.3 0.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN09020.1 - 0.029 14.7 6.2 0.98 9.8 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN09020.1 - 0.72 10.3 9.1 0.83 10.1 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-ANAPC11 PF12861.7 GAN09021.1 - 0.0065 16.5 0.4 0.012 15.7 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SR-25 PF10500.9 GAN09021.1 - 0.28 10.8 30.4 0.55 9.8 8.2 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein zf-RING_2 PF13639.6 GAN09022.1 - 4e-08 33.5 5.0 1e-07 32.2 5.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAN09022.1 - 9.7e-07 29.0 3.7 2.9e-06 27.5 3.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAN09022.1 - 6.1e-06 26.0 3.3 1.4e-05 24.9 3.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 GAN09022.1 - 0.00012 22.7 0.7 0.026 15.4 0.3 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 GAN09022.1 - 0.00021 21.2 3.0 0.00061 19.8 3.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAN09022.1 - 0.00046 20.3 1.6 0.0018 18.4 1.4 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAN09022.1 - 0.00051 19.8 5.0 0.001 18.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN09022.1 - 0.00073 19.5 2.2 0.0033 17.4 2.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAN09022.1 - 0.00081 19.3 4.2 0.0017 18.3 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAN09022.1 - 0.015 15.1 5.3 0.083 12.8 5.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN09022.1 - 0.019 14.8 6.0 0.022 14.6 3.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 GAN09022.1 - 0.063 13.1 0.3 0.2 11.5 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 GAN09022.1 - 0.16 11.7 6.7 0.048 13.4 3.6 1.8 2 0 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 GAN09022.1 - 0.36 11.0 5.3 1 9.6 5.3 1.8 1 0 0 1 1 1 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 GAN09022.1 - 0.83 9.3 5.8 1.7 8.4 5.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Vps52 PF04129.12 GAN09023.1 - 1e-134 450.1 9.5 1.6e-134 449.5 9.5 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 GAN09023.1 - 4.8e-07 28.6 1.0 4.8e-07 28.6 1.0 3.1 3 0 0 3 3 3 2 Exocyst complex component Sec3 COG2 PF06148.11 GAN09023.1 - 0.0012 18.9 2.5 0.0037 17.3 2.5 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 UPF0449 PF15136.6 GAN09023.1 - 0.28 11.7 2.4 0.99 9.9 2.4 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 GCIP PF13324.6 GAN09023.1 - 1.2 8.6 7.5 2.4 7.7 7.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Fib_alpha PF08702.10 GAN09023.1 - 3.6 7.8 6.6 2 8.6 3.2 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Collagen PF01391.18 GAN09024.1 - 0.00042 20.0 9.8 0.00042 20.0 9.8 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Polysacc_deac_1 PF01522.21 GAN09024.1 - 0.042 13.7 0.2 0.09 12.7 0.2 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF2457 PF10446.9 GAN09024.1 - 4.3 6.4 14.2 11 5.1 14.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PH PF00169.29 GAN09025.1 - 5.2e-11 43.0 2.5 3.3e-10 40.4 0.1 2.9 3 1 0 3 3 3 1 PH domain PH_9 PF15410.6 GAN09025.1 - 2.8e-05 24.5 0.2 0.00019 21.8 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain ORC_WH_C PF18137.1 GAN09025.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal PP2C PF00481.21 GAN09026.1 - 2.8e-52 177.9 0.4 9.5e-52 176.2 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 GAN09026.1 - 1.6e-37 127.1 57.1 2e-08 33.9 6.6 10.3 8 2 1 10 10 10 7 Leucine rich repeat Guanylate_cyc PF00211.20 GAN09026.1 - 5.2e-29 101.2 0.0 1.7e-28 99.5 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 GAN09026.1 - 6e-29 99.6 70.9 0.00074 19.9 1.3 13.4 3 2 7 14 14 14 12 Leucine Rich repeats (2 copies) RA PF00788.23 GAN09026.1 - 4.5e-09 36.8 0.1 1.7e-08 35.0 0.1 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.6 GAN09026.1 - 0.0016 18.4 3.9 0.29 11.1 0.6 3.5 3 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) TFIIA PF03153.13 GAN09026.1 - 0.53 10.2 35.7 0.023 14.7 9.1 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRR_9 PF14580.6 GAN09026.1 - 1.7 8.1 20.2 2.2 7.7 0.3 5.1 3 1 1 5 5 5 0 Leucine-rich repeat LRR_1 PF00560.33 GAN09026.1 - 2.7 8.9 50.9 5.3 8.0 0.2 13.3 15 0 0 15 15 15 0 Leucine Rich Repeat Pkinase PF00069.25 GAN09027.1 - 5e-62 209.7 0.0 3.6e-61 206.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09027.1 - 9e-45 153.0 0.0 1.8e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN09027.1 - 5.5e-06 25.4 1.3 1e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAN09027.1 - 1.1e-05 24.9 0.0 2.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like UPF0449 PF15136.6 GAN09027.1 - 0.017 15.6 10.0 0.03 14.8 4.9 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 APH PF01636.23 GAN09027.1 - 0.052 13.5 0.0 0.28 11.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family YabA PF06156.13 GAN09027.1 - 0.77 10.4 11.2 0.042 14.5 4.7 2.4 2 1 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 GAN09027.1 - 1.8 8.8 9.4 1.1 9.5 6.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 GAN09027.1 - 9 6.5 13.0 1.8 8.8 7.8 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Metallophos PF00149.28 GAN09028.1 - 2e-35 123.2 0.2 3.2e-35 122.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAN09028.1 - 2.5e-14 53.4 0.0 4.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BTB PF00651.31 GAN09029.1 - 5.5e-08 33.0 0.1 2.9e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain RXT2_N PF08595.11 GAN09029.1 - 0.13 12.2 6.4 8.1 6.4 0.0 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 GAN09029.1 - 6.6 6.0 7.2 12 5.1 7.2 1.3 1 0 0 1 1 1 0 NOA36 protein Kei1 PF08552.11 GAN09031.1 - 0.57 10.0 4.1 3.8 7.4 4.1 1.9 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Phosphodiest PF01663.22 GAN09032.1 - 3.7e-86 289.9 0.4 4.5e-86 289.6 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAN09032.1 - 3.1e-06 26.8 0.0 0.0028 17.1 0.1 2.4 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 GAN09032.1 - 0.0097 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily HA70_C PF17993.1 GAN09033.1 - 0.062 13.4 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain zf-MIZ PF02891.20 GAN09034.1 - 1.3e-18 66.5 2.6 2.8e-18 65.4 2.6 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Zmiz1_N PF18028.1 GAN09034.1 - 1.2e-10 41.6 0.1 4.4e-10 39.8 0.1 2.0 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain zf-Nse PF11789.8 GAN09034.1 - 3.9e-06 26.6 0.8 1.3e-05 24.9 0.8 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PhnA_Zn_Ribbon PF08274.12 GAN09034.1 - 0.099 12.6 0.2 0.35 10.9 0.2 1.9 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-C3HC4_2 PF13923.6 GAN09034.1 - 0.51 10.2 2.5 1.2 9.0 2.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S5 PF00333.20 GAN09035.1 - 2.3e-28 98.0 1.7 2.3e-28 98.0 1.7 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAN09035.1 - 1.7e-19 69.1 0.2 3e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Phage_tail_NK PF16532.5 GAN09035.1 - 0.14 11.8 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Claudin_2 PF13903.6 GAN09036.1 - 0.0017 18.2 2.6 0.0017 18.2 2.6 2.5 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Saf_2TM PF18303.1 GAN09036.1 - 0.019 14.6 1.8 0.033 13.8 1.8 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain EF-hand_1 PF00036.32 GAN09037.1 - 1.5e-31 105.6 6.4 1.1e-08 34.0 0.1 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 GAN09037.1 - 1.5e-25 89.5 10.2 3e-12 46.8 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN09037.1 - 6.5e-23 78.7 5.8 1.7e-05 24.3 0.2 5.0 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAN09037.1 - 1.1e-21 75.3 8.1 2.3e-06 26.8 0.1 4.9 4 2 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAN09037.1 - 2.1e-19 69.1 7.7 6.8e-07 29.0 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 GAN09037.1 - 3.1e-12 46.4 7.6 2.8e-06 27.2 0.6 3.6 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN09037.1 - 3.3e-06 27.4 6.4 0.00084 19.6 2.2 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAN09037.1 - 4.3e-05 23.6 0.4 5.4 7.3 0.0 4.0 3 1 1 4 4 4 1 Dockerin type I domain EF-hand_9 PF14658.6 GAN09037.1 - 0.00015 22.0 0.3 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain TerB PF05099.13 GAN09037.1 - 0.0011 18.9 1.0 1.4 8.9 0.1 3.1 2 1 1 3 3 3 1 Tellurite resistance protein TerB FGAR-AT_linker PF18072.1 GAN09037.1 - 0.0056 17.2 1.2 0.014 15.9 0.1 2.2 3 0 0 3 3 3 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF2666 PF10869.8 GAN09037.1 - 0.033 14.4 0.2 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) SabA_adhesion PF18304.1 GAN09037.1 - 0.061 12.5 1.7 0.72 9.0 0.2 2.1 1 1 1 2 2 2 0 SabA N-terminal extracellular adhesion domain VCBS PF13517.6 GAN09037.1 - 0.11 13.1 2.2 31 5.3 0.1 3.1 2 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.32 GAN09038.1 - 2.1e-25 86.3 13.4 2e-09 36.3 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN09038.1 - 2.4e-22 79.1 8.6 3.4e-16 59.5 1.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN09038.1 - 3.6e-21 73.2 8.1 2.5e-08 33.2 0.3 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 GAN09038.1 - 6.5e-19 66.5 12.8 1.5e-07 30.6 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAN09038.1 - 5.6e-17 61.3 12.4 2.1e-09 37.1 0.8 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 GAN09038.1 - 1.6e-07 31.2 1.6 0.00061 19.7 0.4 2.9 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN09038.1 - 0.00013 22.2 1.3 0.051 13.9 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAN09038.1 - 0.00015 22.0 0.2 0.13 12.6 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain Toprim_2 PF13155.6 GAN09038.1 - 0.011 16.1 0.4 2.5 8.6 0.0 2.4 1 1 1 2 2 2 0 Toprim-like Dockerin_1 PF00404.18 GAN09038.1 - 0.016 15.4 1.4 1.2 9.4 0.4 2.6 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_14 PF17959.1 GAN09038.1 - 0.031 14.6 0.4 0.77 10.1 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 GAN09038.1 - 0.041 13.8 0.6 9.8 6.1 0.0 2.7 2 1 1 3 3 3 0 Caleosin related protein SLS PF14611.6 GAN09039.1 - 4.8e-17 62.5 2.2 4.8e-17 62.5 2.2 1.8 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 GAN09039.1 - 1.8e-06 27.6 0.0 4.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 KH domain RasGEF PF00617.19 GAN09040.1 - 1e-50 172.4 0.9 3.3e-50 170.7 0.9 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN09040.1 - 7e-14 51.9 2.3 7e-14 51.9 2.3 3.4 3 0 0 3 3 3 1 RasGEF N-terminal motif Croc_4 PF17691.1 GAN09040.1 - 0.024 14.7 7.2 3.2 7.8 0.0 3.9 3 0 0 3 3 3 0 Contingent replication of cDNA 4 RNR_Alpha PF17975.1 GAN09040.1 - 0.095 13.2 0.2 0.55 10.8 0.2 2.3 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain MRC1 PF09444.10 GAN09041.1 - 6e-24 85.2 13.6 6e-24 85.2 13.6 8.4 4 2 3 7 7 7 1 MRC1-like domain TFIIS_M PF07500.14 GAN09042.1 - 7.1e-24 84.4 0.1 7.1e-24 84.4 0.1 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GAN09042.1 - 1.1e-18 66.8 7.6 1.1e-18 66.8 7.6 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GAN09042.1 - 3.4e-09 36.6 1.3 9.6e-09 35.1 1.3 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PH PF00169.29 GAN09042.1 - 1.6e-08 35.0 0.6 1.6e-07 31.7 0.2 2.9 3 0 0 3 3 3 1 PH domain RA PF00788.23 GAN09042.1 - 2.8e-07 31.1 0.1 2.8e-07 31.1 0.1 2.9 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Ead_Ea22 PF13935.6 GAN09042.1 - 0.018 15.7 0.2 0.018 15.7 0.2 2.6 3 0 0 3 3 3 0 Ead/Ea22-like protein CBFB_NFYA PF02045.15 GAN09043.1 - 2.8e-29 101.5 5.4 2.8e-29 101.5 5.4 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Beta-lactamase2 PF13354.6 GAN09043.1 - 0.17 11.5 1.6 0.32 10.6 1.4 1.9 1 1 0 1 1 1 0 Beta-lactamase enzyme family Pex14_N PF04695.13 GAN09043.1 - 0.65 10.6 23.8 0.93 10.1 7.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LINES_N PF14694.6 GAN09044.1 - 3.2e-09 36.7 0.4 6.1e-09 35.8 0.4 1.4 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 GAN09044.1 - 0.045 13.2 0.8 0.15 11.5 0.2 2.2 2 0 0 2 2 2 0 Lines C-terminus Thiolase_N PF00108.23 GAN09045.1 - 6.8e-75 251.8 5.6 6.8e-75 251.8 5.6 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN09045.1 - 4.3e-47 158.8 0.2 1.1e-46 157.5 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAN09045.1 - 0.098 12.2 5.6 0.33 10.5 4.4 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain WD40 PF00400.32 GAN09046.1 - 4.2e-16 59.0 11.8 0.012 16.5 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09046.1 - 1.4e-06 28.5 0.0 0.028 14.7 0.0 5.1 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN09046.1 - 0.0048 16.8 0.0 0.74 9.7 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN09046.1 - 0.0078 15.2 0.1 1.4 7.8 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3246 PF11596.8 GAN09046.1 - 0.022 14.2 7.4 0.044 13.2 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Isy1 PF06246.12 GAN09046.1 - 0.084 12.4 10.9 0.18 11.4 10.9 1.4 1 0 0 1 1 1 0 Isy1-like splicing family NOA36 PF06524.12 GAN09046.1 - 1.1 8.5 17.1 2 7.6 17.1 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 GAN09046.1 - 1.1 9.2 9.5 3.2 7.7 9.5 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Vfa1 PF08432.10 GAN09046.1 - 1.3 9.3 13.4 3.3 8.0 13.4 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPL5 PF18168.1 GAN09046.1 - 5.7 6.1 8.7 9.8 5.4 8.7 1.3 1 0 0 1 1 1 0 Prim-pol family 5 PPP4R2 PF09184.11 GAN09046.1 - 5.7 6.4 19.1 11 5.5 19.1 1.4 1 0 0 1 1 1 0 PPP4R2 COG4 PF08318.12 GAN09047.1 - 5.1e-89 298.7 3.5 5.1e-89 298.7 3.5 1.6 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 GAN09047.1 - 0.00012 21.1 4.9 0.00012 21.1 4.9 2.6 3 1 0 3 3 3 1 RINT-1 / TIP-1 family Vps53_N PF04100.12 GAN09047.1 - 0.00049 19.2 5.6 0.0015 17.6 5.6 1.7 1 0 0 1 1 1 1 Vps53-like, N-terminal DNTTIP1_dimer PF18192.1 GAN09047.1 - 0.013 15.8 0.3 0.082 13.3 0.3 2.5 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain DUF4164 PF13747.6 GAN09047.1 - 0.03 14.6 1.2 0.03 14.6 1.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TPR_2 PF07719.17 GAN09047.1 - 0.11 12.6 0.2 0.53 10.5 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAN09047.1 - 0.11 12.2 0.8 0.36 10.5 0.8 1.9 1 0 0 1 1 1 0 TPR repeat Syntaxin_2 PF14523.6 GAN09047.1 - 0.82 10.1 6.7 0.59 10.5 2.5 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Fez1 PF06818.15 GAN09047.1 - 1.9 8.9 8.0 0.49 10.8 4.1 2.0 2 0 0 2 2 2 0 Fez1 FapA PF03961.13 GAN09047.1 - 8.3 4.9 10.2 0.3 9.7 3.7 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A IBN_N PF03810.19 GAN09048.1 - 0.047 13.6 0.2 18 5.4 0.0 3.5 3 0 0 3 3 3 0 Importin-beta N-terminal domain PH_11 PF15413.6 GAN09048.1 - 0.073 13.5 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Ndc80_HEC PF03801.13 GAN09048.1 - 0.092 12.4 0.7 0.3 10.7 0.2 2.1 2 0 0 2 2 2 0 HEC/Ndc80p family Scm3 PF10384.9 GAN09048.1 - 0.1 12.4 0.4 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 Centromere protein Scm3 Elong_Iki1 PF10483.9 GAN09049.1 - 1.5e-52 179.0 0.4 1.8e-52 178.8 0.4 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Coa1 PF08695.10 GAN09050.1 - 2.5e-24 85.2 0.2 4.7e-24 84.4 0.1 1.4 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Abhydrolase_2 PF02230.16 GAN09052.1 - 3.4e-52 177.4 0.0 4.1e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 GAN09052.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 GAN09052.1 - 0.00023 20.7 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAN09052.1 - 0.00046 19.8 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAN09052.1 - 0.00088 18.6 0.1 0.011 15.0 0.0 2.4 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 GAN09052.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2920 PF11144.8 GAN09052.1 - 0.06 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Zn_clus PF00172.18 GAN09053.1 - 0.00033 20.7 9.5 0.00082 19.4 9.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Enamelin PF15362.6 GAN09053.1 - 1.5 7.0 4.0 2.2 6.5 4.0 1.1 1 0 0 1 1 1 0 Enamelin ABC_membrane PF00664.23 GAN09054.1 - 6.8e-109 363.7 24.9 1.1e-55 189.3 9.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN09054.1 - 1.9e-68 229.2 0.1 8.6e-34 117.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN09054.1 - 3.1e-14 52.9 0.5 1.9e-06 27.5 0.0 4.2 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN09054.1 - 1.7e-08 34.8 1.2 0.0064 16.8 0.2 3.8 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 GAN09054.1 - 2.5e-08 33.2 0.5 0.00048 19.0 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GAN09054.1 - 1.9e-06 28.4 2.8 0.065 13.6 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAN09054.1 - 2.9e-06 27.3 0.0 0.052 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 GAN09054.1 - 6e-06 26.3 0.0 0.046 13.6 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 GAN09054.1 - 3.8e-05 23.5 0.7 0.48 10.1 0.3 3.7 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 GAN09054.1 - 5.4e-05 23.6 3.6 0.33 11.4 0.7 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAN09054.1 - 0.00012 21.8 4.2 0.17 11.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 GAN09054.1 - 0.00022 21.4 0.0 0.19 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GAN09054.1 - 0.00026 20.3 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 GAN09054.1 - 0.00039 19.8 0.1 0.17 11.1 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 GAN09054.1 - 0.00054 20.5 0.0 1.3 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAN09054.1 - 0.00083 18.9 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 GAN09054.1 - 0.0014 18.8 3.8 1.5 9.1 0.4 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 GAN09054.1 - 0.0015 18.8 2.4 2.3 8.4 0.1 3.9 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 GAN09054.1 - 0.0047 17.3 0.0 5.3 7.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 GAN09054.1 - 0.0097 15.6 0.0 0.59 9.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 GAN09054.1 - 0.011 15.4 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Tim17 PF02466.19 GAN09054.1 - 0.02 15.3 0.2 0.43 11.0 0.0 3.1 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family AAA_5 PF07728.14 GAN09054.1 - 0.02 14.9 0.2 11 6.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 GAN09054.1 - 0.021 14.6 0.1 69 3.1 0.0 3.9 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 GAN09054.1 - 0.022 14.4 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 GAN09054.1 - 0.023 13.9 0.0 0.39 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.18 GAN09054.1 - 0.054 13.2 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 GAN09054.1 - 0.055 13.4 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 GAN09054.1 - 0.069 12.7 0.5 8 6.0 0.2 3.2 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 GAN09054.1 - 0.13 12.0 0.1 7.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 GAN09054.1 - 0.17 12.3 6.8 5.2 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 GAN09054.1 - 0.18 11.6 1.6 24 4.6 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein RFC1 PF08519.12 GAN09055.1 - 7.3e-53 178.9 0.0 2.8e-50 170.5 0.0 2.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 GAN09055.1 - 5e-12 46.4 0.0 1.4e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 GAN09055.1 - 1.3e-10 41.5 0.0 3.7e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 GAN09055.1 - 1.7e-09 37.8 0.0 4.4e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GAN09055.1 - 6.9e-05 23.1 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAN09055.1 - 0.00091 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAN09055.1 - 0.0015 19.1 0.0 0.0053 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain BRCT_2 PF16589.5 GAN09055.1 - 0.0027 18.1 0.0 0.0072 16.7 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain AAA_7 PF12775.7 GAN09055.1 - 0.003 17.1 0.0 0.01 15.4 0.0 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 GAN09055.1 - 0.0046 16.7 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN09055.1 - 0.0048 17.3 0.0 0.036 14.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 GAN09055.1 - 0.0063 16.4 0.1 0.13 12.2 0.1 2.8 2 1 0 2 2 2 1 NACHT domain DNA_pol3_delta PF06144.13 GAN09055.1 - 0.011 15.6 1.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 GAN09055.1 - 0.015 15.3 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 GAN09055.1 - 0.029 14.5 0.0 0.094 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAN09055.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 GAN09055.1 - 0.059 13.3 0.1 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 GAN09055.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAN09055.1 - 0.13 11.5 0.0 0.32 10.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 GAN09055.1 - 0.14 12.6 0.1 2.7 8.4 0.0 3.1 4 0 0 4 4 3 0 RNA helicase TPT PF03151.16 GAN09056.1 - 4.6e-47 160.8 27.2 5.6e-47 160.5 27.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAN09056.1 - 2.6e-15 56.4 26.2 3.2e-15 56.1 26.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAN09056.1 - 8.8e-10 38.9 33.9 4.2e-05 23.7 12.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAN09056.1 - 0.00028 20.1 10.3 0.0015 17.8 1.9 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter NDK PF00334.19 GAN09057.1 - 2.2e-52 176.6 0.0 2.6e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Mito_carr PF00153.27 GAN09058.1 - 1.1e-53 179.1 7.0 8e-21 73.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein 3-HAO PF06052.12 GAN09059.1 - 4.5e-35 120.5 0.4 5.2e-35 120.3 0.4 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 GAN09059.1 - 1.2e-05 24.9 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAN09059.1 - 0.00032 20.3 0.0 0.0004 20.0 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 GAN09059.1 - 0.029 14.1 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAN09059.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain PI3_PI4_kinase PF00454.27 GAN09060.1 - 3.7e-54 184.2 0.1 2.6e-53 181.4 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 GAN09060.1 - 2.1e-34 119.1 0.5 5.6e-34 117.7 0.5 1.8 1 0 0 1 1 1 1 NUC194 domain FATC PF02260.20 GAN09060.1 - 4.6e-10 39.1 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 GAN09060.1 - 0.038 14.3 0.7 11 6.7 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat SUIM_assoc PF16619.5 GAN09060.1 - 2.3 8.4 7.8 14 5.9 7.8 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Rtf2 PF04641.12 GAN09062.1 - 5.5e-77 258.7 8.3 6.6e-77 258.4 8.3 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger DUF2256 PF10013.9 GAN09062.1 - 0.0035 17.4 0.1 0.0085 16.2 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.6 GAN09062.1 - 0.0075 16.2 2.8 0.0078 16.2 0.4 2.1 1 1 1 2 2 2 1 YhfH-like protein zf-Nse PF11789.8 GAN09062.1 - 0.01 15.6 0.5 0.36 10.7 0.0 2.5 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF935 PF06074.12 GAN09062.1 - 0.014 14.2 3.9 0.023 13.5 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF935) zf-NOSIP PF15906.5 GAN09062.1 - 0.063 13.4 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein RNase_PH_C PF03725.15 GAN09062.1 - 0.085 12.9 0.0 0.38 10.8 0.0 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Drf_GBD PF06371.13 GAN09062.1 - 0.33 10.5 5.4 0.45 10.1 4.5 1.6 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain DUF3987 PF13148.6 GAN09062.1 - 1.9 7.4 5.3 2.8 6.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MAJIN PF15077.6 GAN09062.1 - 4 7.1 8.6 9 6.0 8.4 1.6 1 1 0 1 1 1 0 Membrane-anchored junction protein DUF2277 PF10041.9 GAN09063.1 - 0.46 10.8 6.1 12 6.3 0.7 3.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) YjeF_N PF03853.15 GAN09063.1 - 1.2 9.0 3.8 1.4 8.7 0.6 2.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Pkinase PF00069.25 GAN09064.1 - 9.8e-53 179.2 0.1 1.8e-52 178.3 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09064.1 - 1.8e-19 70.0 0.0 4.3e-19 68.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4476 PF14771.6 GAN09064.1 - 0.093 13.0 0.2 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) PepSY_TM_like_2 PF16357.5 GAN09064.1 - 0.16 12.0 0.3 0.26 11.2 0.3 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like ABC_tran PF00005.27 GAN09065.1 - 1.2e-27 97.1 0.0 1.9e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAN09065.1 - 3.8e-08 33.5 0.0 8.2e-05 22.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN09065.1 - 3.6e-05 23.3 0.0 0.00043 19.8 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAN09065.1 - 0.00011 22.7 0.0 0.00019 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAN09065.1 - 0.00071 19.5 0.0 0.0016 18.4 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 GAN09065.1 - 0.0014 18.6 0.1 0.005 16.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 GAN09065.1 - 0.0023 17.3 0.0 0.046 13.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 GAN09065.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAN09065.1 - 0.0081 16.4 0.0 0.26 11.6 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 GAN09065.1 - 0.0087 15.8 0.0 0.035 13.8 0.0 1.9 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAN09065.1 - 0.011 15.7 0.0 0.064 13.2 0.0 1.8 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAN09065.1 - 0.012 15.6 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAN09065.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAN09065.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAN09065.1 - 0.022 15.2 0.1 0.072 13.5 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAN09065.1 - 0.042 14.1 0.0 0.072 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAN09065.1 - 0.044 14.3 0.0 0.074 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAN09065.1 - 0.044 14.1 0.0 0.89 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAN09065.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 GAN09065.1 - 0.068 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAN09065.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAN09065.1 - 0.098 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 GAN09065.1 - 0.1 13.2 0.0 0.14 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAN09065.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AFG1_ATPase PF03969.16 GAN09065.1 - 0.22 10.4 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase Methyltransf_PK PF05891.12 GAN09066.1 - 2.5e-78 262.6 0.1 2.9e-78 262.3 0.1 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 GAN09066.1 - 8.3e-11 42.5 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN09066.1 - 5.2e-10 39.4 0.1 1.2e-09 38.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN09066.1 - 8.1e-08 32.8 0.0 1.6e-07 31.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN09066.1 - 9e-08 32.8 0.0 1.4e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN09066.1 - 2.1e-05 24.4 0.2 3.1e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAN09066.1 - 0.00031 20.1 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 GAN09066.1 - 0.0074 15.8 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAN09066.1 - 0.066 12.5 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Molybdopterin PF00384.22 GAN09067.1 - 5.2e-69 233.3 0.0 3.5e-68 230.5 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 GAN09067.1 - 4.9e-19 68.2 0.1 3e-18 65.6 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 GAN09067.1 - 4.7e-16 58.0 0.2 4.7e-16 58.0 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 GAN09067.1 - 1e-14 55.0 0.2 2.6e-14 53.6 0.2 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 GAN09067.1 - 7.5e-08 32.2 0.3 7.5e-08 32.2 0.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 GAN09067.1 - 0.0058 16.4 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF4108 PF13390.6 GAN09067.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) zf-H2C2_2 PF13465.6 GAN09068.1 - 4.1e-08 33.3 0.1 4.1e-08 33.3 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 GAN09068.1 - 7.9e-08 32.4 8.9 0.00012 22.3 3.1 3.5 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN09068.1 - 8e-05 23.2 7.4 0.0021 18.7 2.9 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger SelP_N PF04592.14 GAN09068.1 - 0.0096 15.3 14.7 0.014 14.9 13.9 1.7 2 0 0 2 2 2 1 Selenoprotein P, N terminal region Zip PF02535.22 GAN09068.1 - 0.073 12.3 2.7 0.084 12.1 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 GAN09068.1 - 0.1 12.6 6.0 0.093 12.7 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_2 PF12756.7 GAN09068.1 - 0.12 12.8 0.5 0.12 12.8 0.5 3.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) NicO PF03824.16 GAN09068.1 - 7 5.9 9.0 11 5.3 9.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein JAB PF01398.21 GAN09069.1 - 8.6e-15 54.7 0.0 4e-14 52.6 0.0 2.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rad21_Rec8_N PF04825.13 GAN09069.1 - 2.3e-05 24.5 0.1 6.2e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAN09069.1 - 0.0002 20.6 0.1 0.0002 20.6 0.1 2.3 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein BRCC36_C PF18110.1 GAN09069.1 - 0.00039 20.5 0.5 0.0014 18.8 0.5 2.0 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 GAN09069.1 - 0.0013 18.5 0.3 0.0043 16.8 0.3 1.9 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain FAM195 PF14799.6 GAN09069.1 - 6.7 7.1 6.4 2.1 8.7 0.0 3.3 4 0 0 4 4 4 0 FAM195 family WD40 PF00400.32 GAN09071.1 - 3.2e-09 37.3 14.2 0.007 17.2 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat F-box-like PF12937.7 GAN09071.1 - 7.6e-09 35.3 0.7 1.8e-08 34.2 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN09071.1 - 1.1e-08 34.7 0.3 2.6e-08 33.5 0.3 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 GAN09071.1 - 0.00031 19.5 2.2 0.18 10.4 1.1 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Methyltransf_34 PF11312.8 GAN09071.1 - 0.053 12.8 0.7 0.1 11.8 0.7 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF5615 PF18480.1 GAN09071.1 - 0.14 12.0 0.0 31 4.4 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5615) UCH PF00443.29 GAN09072.1 - 8.1e-33 114.0 5.1 8.1e-33 114.0 5.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN09072.1 - 8.1e-17 61.8 7.2 2.6e-16 60.1 7.2 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase_Tyr PF07714.17 GAN09072.1 - 3.1e-06 26.7 0.3 0.082 12.2 0.6 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAN09072.1 - 4.3e-06 26.3 3.5 0.042 13.2 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain zf-RING_2 PF13639.6 GAN09073.1 - 7.6e-13 48.6 7.1 1.3e-12 47.8 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN09073.1 - 1.8e-07 30.9 6.6 3.4e-07 30.0 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN09073.1 - 7.5e-07 29.3 7.6 2e-06 28.0 7.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAN09073.1 - 9.1e-07 28.6 4.9 1.7e-06 27.8 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN09073.1 - 7.2e-06 25.9 4.4 1.2e-05 25.1 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAN09073.1 - 9.4e-06 25.3 2.4 2e-05 24.2 2.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAN09073.1 - 2.5e-05 24.2 9.9 5.6e-05 23.1 9.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAN09073.1 - 2.7e-05 23.9 9.1 4.9e-05 23.1 9.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAN09073.1 - 0.00036 20.3 8.1 0.00061 19.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 GAN09073.1 - 0.017 15.3 0.1 0.066 13.4 0.0 2.0 2 0 0 2 2 1 0 U-box domain KLRAQ PF10205.9 GAN09073.1 - 0.088 13.1 11.0 0.55 10.5 1.5 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein zf-C3HC4_4 PF15227.6 GAN09073.1 - 0.12 12.6 5.5 0.28 11.4 5.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 GAN09073.1 - 0.19 11.9 3.1 0.45 10.7 3.1 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 GAN09073.1 - 0.2 11.9 6.4 1.6 9.0 6.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DUF5320 PF17253.2 GAN09073.1 - 0.21 12.6 1.8 6 8.0 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Zn_ribbon_17 PF17120.5 GAN09073.1 - 0.28 10.8 6.6 0.54 9.9 6.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAN09073.1 - 0.43 10.7 5.1 0.82 9.8 5.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 GAN09073.1 - 0.63 10.0 7.0 0.28 11.1 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4472 PF14739.6 GAN09073.1 - 4.2 8.1 16.8 4.5 8.0 4.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) CENP-H PF05837.12 GAN09073.1 - 4.3 7.8 18.0 8.5 6.8 3.8 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) zf-C3H2C3 PF17122.5 GAN09073.1 - 8.7 6.5 9.3 3.3 7.8 6.7 1.8 2 0 0 2 2 1 0 Zinc-finger Iwr1 PF08574.10 GAN09076.1 - 2.7e-13 50.7 20.8 2.7e-13 50.7 20.8 3.9 4 1 0 4 4 4 1 Transcription factor Iwr1 Kelch_1 PF01344.25 GAN09077.1 - 1.5e-44 149.3 12.5 2e-08 33.7 0.2 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_4 PF13418.6 GAN09077.1 - 1.7e-41 140.0 11.6 8.7e-10 38.5 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GAN09077.1 - 4e-40 135.2 12.7 1.8e-07 31.0 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAN09077.1 - 8.5e-40 134.3 18.8 2.1e-10 40.6 0.1 7.6 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN09077.1 - 9.5e-33 111.4 18.4 3.1e-05 24.1 0.8 6.8 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAN09077.1 - 1.7e-29 100.6 10.5 7.8e-06 25.7 0.1 6.8 6 0 0 6 6 6 6 Kelch motif Nucleopor_Nup85 PF07575.13 GAN09078.1 - 1.4e-44 152.7 7.5 1.9e-44 152.2 7.5 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin LEF-9 PF05094.12 GAN09078.1 - 0.0053 15.3 1.1 0.0086 14.7 1.1 1.2 1 0 0 1 1 1 1 Late expression factor 9 (LEF-9) CSF-1 PF05337.11 GAN09078.1 - 0.043 13.9 0.6 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) zf-UBR PF02207.20 GAN09079.1 - 1.8e-19 69.6 11.2 1.8e-19 69.6 11.2 2.9 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAN09079.1 - 1.8e-07 30.8 0.1 8.8e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS FAA_hydrolase_N PF09298.11 GAN09079.1 - 0.044 14.0 0.0 0.26 11.5 0.1 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal RabGAP-TBC PF00566.18 GAN09080.1 - 1.1e-51 175.6 1.4 1.1e-51 175.6 1.4 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ala_racemase_N PF01168.20 GAN09081.1 - 5.9e-25 88.2 0.0 6.9e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain BTB PF00651.31 GAN09082.1 - 5.8e-17 61.9 0.1 1.3e-15 57.6 0.0 2.6 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 GAN09082.1 - 0.00014 21.9 0.0 0.00042 20.4 0.0 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Complex1_LYR PF05347.15 GAN09082.1 - 0.1 12.7 0.1 0.76 9.9 0.1 2.2 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Na_Ca_ex PF01699.24 GAN09083.1 - 1.2e-44 151.9 47.5 3.3e-26 92.1 12.9 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein SLC3A2_N PF16028.5 GAN09083.1 - 2.8 7.6 6.1 1.5 8.4 0.6 2.9 2 1 1 3 3 3 0 Solute carrier family 3 member 2 N-terminus DUF3852 PF12963.7 GAN09083.1 - 4.1 7.8 8.0 0.96 9.8 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) Aldo_ket_red PF00248.21 GAN09084.1 - 2.1e-59 201.1 0.0 2.5e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Annexin PF00191.20 GAN09085.1 - 0.14 12.2 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 Annexin bZIP_1 PF00170.21 GAN09086.1 - 1.9e-06 27.9 10.9 3.9e-06 26.9 10.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN09086.1 - 7.2e-05 22.8 16.1 7.5e-05 22.7 12.2 2.2 1 1 1 2 2 2 2 Basic region leucine zipper RasGAP_C PF03836.15 GAN09086.1 - 0.073 13.2 8.0 0.12 12.5 8.0 1.3 1 0 0 1 1 1 0 RasGAP C-terminus M PF02370.16 GAN09086.1 - 0.077 13.6 1.1 0.077 13.6 1.1 2.0 2 0 0 2 2 2 0 M protein repeat YabA PF06156.13 GAN09086.1 - 0.63 10.7 8.1 0.37 11.5 5.7 1.7 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_Maf PF03131.17 GAN09086.1 - 0.69 10.5 14.1 1.1 9.8 14.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.19 GAN09086.1 - 1.7 6.5 6.5 2.3 6.0 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 GAN09086.1 - 3.9 7.3 9.2 0.34 10.7 2.7 2.2 1 1 1 2 2 2 0 Septum formation initiator Phosphodiest PF01663.22 GAN09087.1 - 1.6e-87 294.5 2.0 1.8e-87 294.2 2.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAN09087.1 - 1e-07 31.7 0.3 4.2e-05 23.1 0.1 2.6 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.12 GAN09087.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 PglZ domain Amidohydro_1 PF01979.20 GAN09088.1 - 6.4e-66 223.0 0.0 7.6e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAN09088.1 - 1.7e-08 34.4 0.0 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family HTH_49 PF18010.1 GAN09088.1 - 0.065 13.1 0.6 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 Cry35Ab1 HTH C-terminal domain UPF0113_N PF17833.1 GAN09089.1 - 2.8e-31 107.9 0.1 4.6e-31 107.2 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GAN09089.1 - 2e-24 85.6 0.0 3.1e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain Pkinase PF00069.25 GAN09090.1 - 1.4e-68 231.1 0.0 1.8e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09090.1 - 2.8e-30 105.5 0.0 4.2e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN09090.1 - 1.4e-05 24.2 0.0 1.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN09090.1 - 9.3e-05 21.9 0.1 0.00028 20.3 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN09090.1 - 0.00071 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAN09090.1 - 0.018 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAN09090.1 - 0.032 13.6 0.0 0.2 11.0 0.0 2.0 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.22 GAN09090.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Sel1 PF08238.12 GAN09091.1 - 1.6e-34 117.5 16.1 6.6e-07 29.8 0.0 8.1 8 0 0 8 8 8 6 Sel1 repeat GDYXXLXY PF14345.6 GAN09091.1 - 0.088 12.6 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 GDYXXLXY protein Peptidase_M20 PF01546.28 GAN09092.1 - 4.6e-26 91.8 0.0 7.9e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 GAN09092.1 - 4.4e-23 81.1 20.6 2.6e-06 28.1 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat M20_dimer PF07687.14 GAN09092.1 - 1.3e-10 41.1 0.0 3.8e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 GAN09092.1 - 6.2e-07 28.4 0.6 0.00022 20.0 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN09092.1 - 2.9e-06 27.5 0.3 0.49 10.7 0.0 4.3 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN09092.1 - 4.6e-06 26.2 2.2 0.011 15.1 0.0 3.2 3 1 0 3 3 3 2 WD40-like domain BBS2_Mid PF14783.6 GAN09092.1 - 0.025 14.6 0.0 31 4.7 0.0 3.7 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Lactamase_B_4 PF13691.6 GAN09092.1 - 0.12 12.0 0.0 1.4 8.7 0.0 2.6 3 0 0 3 3 3 0 tRNase Z endonuclease tRNA-synt_2 PF00152.20 GAN09093.1 - 5.7e-70 235.9 0.0 8.5e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAN09093.1 - 1.4e-09 37.8 0.0 4.6e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAN09093.1 - 1.2e-06 28.2 0.0 0.0045 16.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FGase PF05013.12 GAN09094.1 - 2.4e-10 41.0 0.0 0.00067 19.9 0.0 2.7 1 1 1 2 2 2 2 N-formylglutamate amidohydrolase Metallophos_2 PF12850.7 GAN09094.1 - 0.05 13.8 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FixH PF05751.11 GAN09095.1 - 0.086 12.8 2.1 11 6.0 0.3 3.1 3 0 0 3 3 3 0 FixH ADH_zinc_N PF00107.26 GAN09096.1 - 4e-20 72.1 0.0 9.4e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN09096.1 - 2.3e-19 69.3 4.6 3.7e-19 68.6 4.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAN09096.1 - 7.8e-07 28.6 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAN09096.1 - 0.00061 19.2 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAN09096.1 - 0.0024 18.9 0.0 0.0055 17.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ThiF PF00899.21 GAN09096.1 - 0.034 13.5 1.5 0.13 11.6 0.6 2.2 1 1 1 2 2 2 0 ThiF family TrkA_N PF02254.18 GAN09096.1 - 0.057 13.7 0.2 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 GAN09096.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 GAN09096.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain dsDNA_bind PF01984.20 GAN09098.1 - 7.1e-34 116.4 4.4 9.4e-34 116.0 4.4 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TPR_20 PF14561.6 GAN09098.1 - 0.016 15.5 1.7 0.026 14.8 1.7 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-1_beta_acid PF10587.9 GAN09098.1 - 0.12 12.9 1.0 0.12 12.9 1.0 3.0 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Foie-gras_1 PF11817.8 GAN09099.1 - 2.2e-43 148.7 0.0 8.8e-42 143.5 0.0 2.3 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 GAN09099.1 - 7.5e-40 137.3 0.0 4.6e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 GAN09099.1 - 2.2e-05 24.4 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking BatD PF13584.6 GAN09099.1 - 0.0017 17.3 0.0 0.004 16.0 0.0 1.6 1 0 0 1 1 1 1 Oxygen tolerance DUF4707 PF15806.5 GAN09099.1 - 0.0049 15.9 0.0 0.0093 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4707) TPR_12 PF13424.6 GAN09099.1 - 0.0092 16.3 0.6 0.049 13.9 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF881 PF05949.12 GAN09099.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) TPR_1 PF00515.28 GAN09099.1 - 0.15 11.9 0.3 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAN09099.1 - 0.15 12.5 0.0 2.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2553 PF10830.8 GAN09099.1 - 0.24 12.2 0.5 0.66 10.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2553) TPR_2 PF07719.17 GAN09099.1 - 0.26 11.5 2.4 2.2 8.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat VTC PF09359.10 GAN09100.1 - 2.6e-84 282.9 0.4 3.9e-84 282.3 0.4 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 GAN09100.1 - 9.9e-13 48.8 7.1 4.6e-05 23.5 0.5 4.0 2 1 0 3 3 3 3 SPX domain DUF202 PF02656.15 GAN09100.1 - 7.6e-11 42.3 2.5 1.4e-10 41.5 2.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF1664 PF07889.12 GAN09100.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) VTC PF09359.10 GAN09101.1 - 1.2e-40 139.6 0.9 1.2e-40 139.6 0.9 2.2 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAN09101.1 - 5.8e-13 49.1 3.6 5.3e-12 46.0 3.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAN09101.1 - 3.5e-06 27.2 24.6 0.0027 17.7 0.2 3.4 2 1 1 4 4 4 2 SPX domain zf-C2H2_4 PF13894.6 GAN09102.1 - 8.9e-08 32.3 44.6 0.32 11.9 3.7 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 GAN09102.1 - 3.1e-06 27.4 33.3 0.038 14.4 1.8 6.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN09102.1 - 6.3e-05 23.1 42.4 0.004 17.4 0.2 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAN09102.1 - 0.00044 20.5 27.5 0.069 13.5 4.1 6.1 3 2 2 5 5 5 3 C2H2 type zinc-finger (2 copies) CTU2 PF10288.9 GAN09102.1 - 0.014 15.7 0.2 0.014 15.7 0.2 3.9 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2 PF00096.26 GAN09102.1 - 0.031 14.7 46.3 0.089 13.3 1.0 6.5 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 GAN09102.1 - 0.044 13.7 0.2 0.044 13.7 0.2 3.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Ribosomal_S15 PF00312.22 GAN09102.1 - 0.25 11.6 3.0 0.45 10.8 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S15 DUF629 PF04780.12 GAN09102.1 - 0.47 8.9 28.1 0.31 9.5 1.8 5.8 2 1 4 6 6 6 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 GAN09102.1 - 2.7 7.7 14.0 1.5 8.5 0.2 4.1 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain PUL PF08324.11 GAN09104.1 - 1.5e-48 165.4 0.9 3e-48 164.4 0.9 1.5 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 GAN09104.1 - 2.8e-38 130.7 1.4 5.6e-38 129.7 1.4 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) HATPase_c PF02518.26 GAN09104.1 - 5.5e-31 107.4 0.0 1.6e-30 105.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 GAN09104.1 - 1.2e-25 89.3 10.6 4.6e-06 27.3 0.0 7.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Response_reg PF00072.24 GAN09104.1 - 3.3e-25 88.4 0.0 1.6e-24 86.2 0.0 2.3 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase_Tyr PF07714.17 GAN09104.1 - 3.4e-24 85.5 0.0 1.1e-14 54.3 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAN09104.1 - 2.8e-21 76.1 0.0 3.2e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Peripla_BP_4 PF13407.6 GAN09104.1 - 4.9e-16 59.1 0.5 9.5e-09 35.2 0.0 2.9 2 0 0 2 2 2 2 Periplasmic binding protein domain HisKA PF00512.25 GAN09104.1 - 6e-16 58.2 0.0 1.8e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Peripla_BP_1 PF00532.21 GAN09104.1 - 3.4e-06 26.7 0.0 9.8e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Vps5 PF09325.10 GAN09104.1 - 0.29 10.6 3.4 0.11 12.1 0.2 1.9 2 0 0 2 2 2 0 Vps5 C terminal like NCD3G PF07562.14 GAN09104.1 - 0.65 10.0 10.6 0.18 11.8 6.7 2.1 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 GAN09104.1 - 2 8.3 19.7 7.2 6.5 7.8 2.9 1 1 1 2 2 2 0 Putative ephrin-receptor like Myb_DNA-bind_6 PF13921.6 GAN09105.1 - 1.4e-06 28.5 1.9 0.0061 16.8 0.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN09105.1 - 4.8e-06 26.7 3.5 0.0045 17.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain IL28A PF15177.6 GAN09105.1 - 0.28 11.0 6.2 0.036 13.9 2.3 1.6 2 0 0 2 2 2 0 Interleukin-28A NmrA PF05368.13 GAN09106.1 - 4e-16 59.3 0.0 7.1e-16 58.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAN09106.1 - 6.7e-16 58.7 0.0 1.3e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAN09106.1 - 4.8e-05 22.9 0.1 0.00016 21.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAN09106.1 - 0.00011 22.4 0.2 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 GAN09106.1 - 0.0012 17.9 0.1 0.002 17.2 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAN09106.1 - 0.018 14.3 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 GAN09106.1 - 0.032 14.5 0.1 0.091 13.0 0.0 1.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 GAN09106.1 - 0.039 14.4 0.0 0.081 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.6 GAN09107.1 - 3.5e-15 56.4 0.0 6.4e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN09107.1 - 2.6e-13 50.1 0.3 1.2e-12 47.9 0.3 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAN09107.1 - 9.9e-06 25.2 0.2 3.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAN09107.1 - 0.0011 19.2 0.6 0.0034 17.6 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain DapB_N PF01113.20 GAN09107.1 - 0.027 14.6 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 GAN09107.1 - 0.04 12.9 0.2 0.04 12.9 0.2 1.6 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GAN09107.1 - 0.051 14.0 0.1 0.14 12.6 0.1 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 GAN09107.1 - 0.051 13.0 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_7 PF13241.6 GAN09107.1 - 0.086 13.3 0.1 0.18 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 GAN09107.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Vac14_Fig4_bd PF11916.8 GAN09108.1 - 1.7e-80 268.9 10.0 1.7e-80 268.9 10.0 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 GAN09108.1 - 1.4e-46 157.0 0.5 2e-40 137.3 0.0 4.5 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAN09108.1 - 4.3e-13 48.3 3.1 0.02 15.1 0.0 7.2 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 GAN09108.1 - 5.7e-09 36.3 0.4 0.46 11.0 0.0 7.1 6 1 1 7 7 7 2 HEAT-like repeat Arm PF00514.23 GAN09108.1 - 1.9e-07 30.9 0.1 8.7 6.6 0.0 5.8 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GAN09108.1 - 2.8e-05 24.2 5.8 0.52 10.4 0.2 4.9 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 GAN09108.1 - 0.0029 17.2 5.2 0.7 9.4 0.0 4.2 4 1 1 5 5 5 2 CLASP N terminal TFCD_C PF12612.8 GAN09108.1 - 0.012 15.5 0.0 0.048 13.5 0.0 2.2 1 1 0 1 1 1 0 Tubulin folding cofactor D C terminal TnpV PF14198.6 GAN09108.1 - 0.3 11.1 3.7 1.2 9.1 3.7 2.1 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Cauli_DNA-bind PF03310.13 GAN09108.1 - 5.5 7.1 7.8 0.56 10.3 1.6 2.6 3 1 0 3 3 3 0 Caulimovirus DNA-binding protein RhoGEF PF00621.20 GAN09109.1 - 1.5e-28 100.3 1.8 1.5e-28 100.3 1.8 3.3 4 0 0 4 4 4 1 RhoGEF domain ANAPC4_WD40 PF12894.7 GAN09110.1 - 3.3e-06 27.3 0.0 0.077 13.3 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN09110.1 - 0.00013 22.7 0.1 0.11 13.4 0.0 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat CNH PF00780.22 GAN09110.1 - 0.021 14.5 5.3 2.1 7.9 0.3 2.8 1 1 1 2 2 2 0 CNH domain Ge1_WD40 PF16529.5 GAN09110.1 - 0.038 13.0 0.1 0.11 11.4 0.1 1.8 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 GAN09110.1 - 0.044 13.5 1.7 8.1 6.1 0.0 3.1 3 1 0 3 3 3 0 TUP1-like enhancer of split WD40_like PF17005.5 GAN09110.1 - 2 7.7 6.6 17 4.6 0.2 3.6 4 1 0 4 4 4 0 WD40-like domain zf-MYND PF01753.18 GAN09111.1 - 2.9e-06 27.2 20.1 4.9e-06 26.5 19.1 1.9 1 1 0 1 1 1 1 MYND finger CCDC53 PF10152.9 GAN09111.1 - 0.00015 22.2 3.7 0.19 12.1 4.2 2.8 2 1 1 3 3 3 2 Subunit CCDC53 of WASH complex Roughex PF06020.11 GAN09111.1 - 0.019 14.1 4.4 0.041 13.0 4.4 1.5 1 0 0 1 1 1 0 Drosophila roughex protein TFB6 PF17110.5 GAN09111.1 - 0.12 12.1 1.3 0.41 10.4 1.3 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF5421 PF17458.2 GAN09111.1 - 0.13 11.7 6.6 0.21 10.9 6.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) TERB2 PF15101.6 GAN09111.1 - 0.15 12.1 7.2 0.37 10.8 7.2 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ecl1 PF12855.7 GAN09111.1 - 0.16 13.1 20.9 0.18 13.0 9.1 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins DcuC PF03606.15 GAN09111.1 - 0.22 10.0 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier TFIIA PF03153.13 GAN09111.1 - 0.24 11.3 20.1 0.041 13.9 9.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 GAN09111.1 - 0.24 11.6 13.0 0.047 14.0 5.3 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CPSF100_C PF13299.6 GAN09111.1 - 0.84 9.8 4.6 0.25 11.5 1.2 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Amino_oxidase PF01593.24 GAN09112.1 - 2.8e-62 211.5 0.1 1.4e-60 205.9 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAN09112.1 - 8.7e-09 35.5 0.0 2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN09112.1 - 4.4e-07 29.4 2.5 0.0065 15.7 0.8 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN09112.1 - 9.3e-07 28.7 0.7 6.9e-05 22.6 0.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAN09112.1 - 2.3e-06 28.0 1.1 0.0032 18.0 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN09112.1 - 8.9e-06 25.3 0.0 0.00048 19.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAN09112.1 - 9.3e-05 21.8 0.7 0.083 12.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN09112.1 - 0.0029 17.6 0.3 0.93 9.5 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 GAN09112.1 - 0.0031 16.6 0.4 0.034 13.2 0.5 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAN09112.1 - 0.009 15.3 0.5 0.009 15.3 0.5 2.1 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 GAN09112.1 - 0.016 14.4 0.2 0.031 13.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GAN09112.1 - 0.029 13.5 1.0 0.043 12.9 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAN09112.1 - 0.091 12.0 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 GAN09112.1 - 0.11 11.3 0.6 1.6 7.5 0.9 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 GAN09112.1 - 0.18 10.4 4.8 1.3 7.6 0.9 3.0 3 0 0 3 3 3 0 HI0933-like protein NOC3p PF07540.11 GAN09113.1 - 1.4e-28 99.2 1.0 1.2e-27 96.2 1.0 2.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 GAN09113.1 - 9.2e-24 84.4 0.1 9.2e-24 84.4 0.1 3.1 3 2 0 3 3 3 1 CBF/Mak21 family eIF-5a PF01287.20 GAN09113.1 - 1.9 8.6 8.1 2.4 8.3 6.0 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold TPR_1 PF00515.28 GAN09114.1 - 3e-42 140.7 23.6 2.2e-08 33.5 0.2 8.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAN09114.1 - 7.2e-39 128.8 20.7 1.5e-05 24.7 0.2 9.8 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.6 GAN09114.1 - 7.3e-29 99.2 23.9 2.4e-07 30.3 1.5 9.6 5 3 4 9 9 9 8 TPR repeat DnaJ PF00226.31 GAN09114.1 - 1.9e-27 95.2 1.5 1.9e-27 95.2 1.5 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.6 GAN09114.1 - 6e-24 84.4 11.0 2.6e-09 37.6 0.2 6.4 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAN09114.1 - 2.3e-22 79.3 14.6 1.6e-05 25.3 0.1 6.1 4 3 2 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAN09114.1 - 1.8e-19 68.2 16.7 0.0045 17.1 0.4 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAN09114.1 - 2e-15 56.1 11.8 0.075 13.9 0.0 8.6 3 3 4 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAN09114.1 - 1.6e-14 54.0 26.4 0.0031 17.7 2.1 8.0 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAN09114.1 - 2.6e-13 49.4 24.3 0.036 14.5 0.2 8.0 9 0 0 9 9 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN09114.1 - 4.5e-11 42.8 18.4 0.00043 20.4 1.1 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GAN09114.1 - 1.2e-08 35.0 9.7 0.014 15.5 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN09114.1 - 1.7e-07 30.9 6.8 0.012 15.0 1.4 4.0 1 1 3 4 4 4 3 MalT-like TPR region TPR_10 PF13374.6 GAN09114.1 - 1.2e-06 28.2 24.2 0.044 13.7 0.1 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAN09114.1 - 5.8e-06 26.6 21.1 1.5 9.6 0.2 7.4 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAN09114.1 - 7.3e-05 22.5 18.8 0.4 10.8 0.1 7.6 6 2 1 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAN09114.1 - 0.00013 21.9 21.5 0.7 10.0 0.0 7.8 6 2 2 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 GAN09114.1 - 0.0084 16.1 18.9 0.061 13.3 0.2 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAN09114.1 - 0.051 13.0 8.5 0.61 9.6 0.0 4.4 4 1 0 4 4 4 0 SHNi-TPR DUF3856 PF12968.7 GAN09114.1 - 0.088 12.9 9.7 12 6.0 0.1 6.0 3 2 2 5 5 5 0 Domain of Unknown Function (DUF3856) Hypoth_Ymh PF09509.10 GAN09114.1 - 0.11 12.4 2.1 0.32 10.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) TAF8_C PF10406.9 GAN09114.1 - 0.63 10.7 3.6 1.9 9.1 0.4 3.0 3 0 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term Alkyl_sulf_dimr PF14863.6 GAN09114.1 - 0.98 9.9 14.1 2.2 8.7 1.3 4.2 3 2 2 5 5 5 0 Alkyl sulfatase dimerisation BTAD PF03704.17 GAN09114.1 - 1.7 9.0 14.0 30 5.0 3.6 4.7 2 2 1 4 4 4 0 Bacterial transcriptional activator domain MIT PF04212.18 GAN09114.1 - 5.3 7.2 24.6 0.16 12.1 2.1 5.8 4 3 1 5 5 5 0 MIT (microtubule interacting and transport) domain BTB_2 PF02214.22 GAN09115.1 - 1.3e-16 60.7 0.0 1.2e-07 32.0 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain zf-C2HC_2 PF13913.6 GAN09115.1 - 0.037 13.9 0.5 0.087 12.8 0.5 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type LptF_LptG PF03739.14 GAN09115.1 - 0.24 10.2 0.3 0.72 8.6 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Cons_hypoth698 PF03601.14 GAN09116.1 - 1.4e-34 119.4 18.0 4.9e-30 104.5 15.4 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 698 Glt_symporter PF03616.14 GAN09116.1 - 0.0027 16.5 5.5 0.0027 16.5 5.5 2.3 2 0 0 2 2 2 2 Sodium/glutamate symporter Pkinase PF00069.25 GAN09117.1 - 3.9e-61 206.7 0.1 5.5e-61 206.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09117.1 - 4e-31 108.3 0.1 5.8e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 GAN09117.1 - 1.6e-11 44.3 13.2 1.6e-11 44.3 13.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN09117.1 - 1.3e-06 28.1 13.9 4.3e-06 26.5 13.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.6 GAN09117.1 - 2.3e-06 27.2 0.0 1.6e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like zf-rbx1 PF12678.7 GAN09117.1 - 3.1e-06 27.4 11.0 3.1e-06 27.4 11.0 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAN09117.1 - 0.00013 21.9 9.0 0.00017 21.6 5.4 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAN09117.1 - 0.00024 20.8 10.1 0.00024 20.8 10.1 2.8 4 0 0 4 4 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAN09117.1 - 0.00029 20.6 12.7 0.00029 20.6 12.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN09117.1 - 0.00034 20.4 8.8 0.00034 20.4 8.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN09117.1 - 0.00073 19.5 5.8 0.00073 19.5 5.8 2.0 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAN09117.1 - 0.0026 17.7 10.8 0.0026 17.7 10.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Pkinase_fungal PF17667.1 GAN09117.1 - 0.021 13.6 0.0 0.021 13.6 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase Zf_RING PF16744.5 GAN09117.1 - 0.06 13.5 6.1 0.13 12.3 6.1 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Peptidase_S49_N PF08496.10 GAN09117.1 - 0.1 12.6 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zn_ribbon_17 PF17120.5 GAN09117.1 - 0.29 10.8 10.4 0.6 9.8 10.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type APH PF01636.23 GAN09117.1 - 0.6 10.0 4.5 1.6 8.6 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-RING_10 PF16685.5 GAN09117.1 - 1.1 9.4 7.6 3 8.0 7.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 GAN09117.1 - 1.3 9.2 11.9 4.7 7.5 11.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 GAN09117.1 - 4.3 7.2 10.4 9.2 6.1 10.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TT_ORF1 PF02956.14 GAN09117.1 - 4.7 5.8 12.5 8.4 4.9 12.5 1.3 1 0 0 1 1 1 0 TT viral orf 1 SAGA-Tad1 PF12767.7 GAN09118.1 - 9.5e-50 169.5 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 GAN09118.1 - 0.0084 15.9 0.8 0.05 13.4 0.0 2.3 2 1 1 3 3 3 1 Transcription initiation factor TFIID component TAF4 family CRAL_TRIO PF00650.20 GAN09119.1 - 8.1e-18 64.6 0.2 1.2e-17 64.1 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain RRM_1 PF00076.22 GAN09120.1 - 6.4e-06 25.9 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corona_nucleoca PF00937.18 GAN09120.1 - 0.00056 19.1 3.9 0.0012 18.0 3.9 1.5 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein RBM39linker PF15519.6 GAN09120.1 - 0.016 16.3 0.2 0.016 16.3 0.2 3.0 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein PI3_PI4_kinase PF00454.27 GAN09121.1 - 1.1e-39 136.7 0.0 1.5e-37 129.8 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAN09121.1 - 1.4e-21 76.8 0.0 3.8e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Anp1 PF03452.14 GAN09122.1 - 8.8e-93 310.5 0.2 1.1e-92 310.3 0.2 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 GAN09122.1 - 7.2e-07 29.2 0.7 4.7e-05 23.2 0.7 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 GAN09122.1 - 0.51 10.9 2.7 0.8 10.3 1.7 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 Copper-fist PF00649.18 GAN09123.1 - 2.8e-11 42.7 3.5 2.8e-11 42.7 3.5 2.5 2 1 1 3 3 3 1 Copper fist DNA binding domain Aldedh PF00171.22 GAN09124.1 - 1.8e-87 293.8 0.0 2.1e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M66 PF10462.9 GAN09124.1 - 0.026 13.5 1.4 0.043 12.8 1.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Pkinase PF00069.25 GAN09125.1 - 3.3e-64 216.8 0.0 5.6e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09125.1 - 1.5e-34 119.4 0.0 2.7e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 GAN09125.1 - 8.7e-19 67.2 29.2 2.2e-11 43.5 10.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 GAN09125.1 - 4.2e-11 42.8 14.2 1.5e-07 31.4 0.5 3.5 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 GAN09125.1 - 1.6e-09 38.3 0.3 6.1e-09 36.4 0.3 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 GAN09125.1 - 7.9e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 GAN09125.1 - 0.13 11.1 2.6 0.39 9.6 0.1 2.3 2 0 0 2 2 2 0 Haspin like kinase domain C1_2 PF03107.16 GAN09125.1 - 0.21 11.9 21.8 0.067 13.5 7.9 2.6 2 0 0 2 2 2 0 C1 domain OMPdecase PF00215.24 GAN09126.1 - 1.1e-79 267.1 0.0 1.3e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family EXS PF03124.14 GAN09127.1 - 1.5e-83 280.9 25.5 1.7e-83 280.7 25.5 1.0 1 0 0 1 1 1 1 EXS family ILVD_EDD PF00920.21 GAN09128.1 - 7e-208 691.4 0.0 8.1e-208 691.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 GAN09128.1 - 0.017 15.4 0.2 8.9 6.7 0.0 3.2 3 0 0 3 3 3 0 FeoA domain Protoglobin PF11563.8 GAN09129.1 - 8.5e-39 133.0 0.1 1.1e-38 132.7 0.1 1.1 1 0 0 1 1 1 1 Protoglobin PhoLip_ATPase_C PF16212.5 GAN09130.1 - 1.3e-83 280.6 24.3 1.3e-83 280.6 24.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAN09130.1 - 6e-25 86.7 4.1 2e-24 85.0 4.1 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAN09130.1 - 2e-13 51.1 0.3 1.7e-08 35.0 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN09130.1 - 2.5e-11 43.5 0.0 9.8e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAN09130.1 - 1.9e-09 37.3 0.0 6e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAN09130.1 - 0.00055 19.8 0.0 0.005 16.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ThiF PF00899.21 GAN09131.1 - 1.8e-68 230.5 0.0 9e-68 228.2 0.0 1.7 1 1 1 2 2 2 1 ThiF family E2_bind PF08825.10 GAN09131.1 - 3.4e-30 104.0 0.3 5.6e-30 103.3 0.3 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 GAN09131.1 - 0.00018 21.5 0.1 0.00044 20.3 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 GAN09131.1 - 0.014 16.0 0.0 0.043 14.4 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ecm33 PF12454.8 GAN09131.1 - 0.02 15.1 0.8 0.054 13.6 0.8 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.27 GAN09131.1 - 0.021 15.3 0.3 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 GAN09131.1 - 0.11 13.1 0.2 0.41 11.3 0.1 2.1 2 0 0 2 2 2 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 GAN09131.1 - 2.3 8.1 5.5 21 4.9 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-activating enzyme active site UTP15_C PF09384.10 GAN09132.1 - 4.7e-05 23.1 0.2 0.0038 16.9 0.1 2.6 1 1 1 2 2 2 2 UTP15 C terminal Utp12 PF04003.12 GAN09132.1 - 0.0064 16.8 0.5 0.051 13.9 0.2 2.5 1 1 1 2 2 2 1 Dip2/Utp12 Family DUF3666 PF12408.8 GAN09132.1 - 0.0096 15.1 0.2 1.3 8.3 0.0 2.7 2 0 0 2 2 2 2 Ribose-5-phosphate isomerase Fasciclin PF02469.22 GAN09133.1 - 4.6e-32 110.9 6.6 6.5e-20 71.7 0.8 2.7 2 1 0 2 2 2 2 Fasciclin domain Seipin PF06775.14 GAN09134.1 - 7e-55 186.2 3.5 9.1e-55 185.8 3.5 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) ABC_trans_CmpB PF06541.11 GAN09134.1 - 0.096 12.9 0.2 0.096 12.9 0.2 2.1 2 0 0 2 2 2 0 Putative ABC-transporter type IV Sigma_reg_N PF13800.6 GAN09134.1 - 0.11 12.8 1.4 16 5.8 0.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DRY_EERY PF09750.9 GAN09135.1 - 1.6e-16 60.8 0.2 1.6e-16 60.8 0.2 4.6 5 1 0 5 5 5 1 Alternative splicing regulator Yippee-Mis18 PF03226.14 GAN09136.1 - 1.9e-07 31.3 0.8 3.5e-07 30.4 0.8 1.4 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF678 PF05077.12 GAN09136.1 - 0.27 11.4 4.3 1.8 8.7 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF678) Peptidase_S9 PF00326.21 GAN09137.1 - 0.00031 20.3 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAN09137.1 - 0.0074 16.1 0.0 0.076 12.8 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ssl1 PF04056.14 GAN09138.1 - 4.3e-83 277.9 0.0 7.3e-83 277.1 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 GAN09138.1 - 1.8e-12 47.9 0.0 4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain F-box-like PF12937.7 GAN09138.1 - 1.4e-07 31.2 0.6 4.1e-07 29.8 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN09138.1 - 1.9e-05 24.4 0.4 1.9e-05 24.4 0.4 2.3 2 0 0 2 2 2 1 F-box domain Tfb4 PF03850.14 GAN09138.1 - 0.00049 19.7 1.1 0.00081 19.0 1.1 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA PF00092.28 GAN09138.1 - 0.0047 17.2 0.0 0.0085 16.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4428 PF14471.6 GAN09138.1 - 0.45 10.5 4.4 2.2 8.2 4.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) DZR PF12773.7 GAN09138.1 - 0.78 9.8 5.7 4.7 7.3 5.9 2.1 1 1 1 2 2 2 0 Double zinc ribbon Asn_synthase PF00733.21 GAN09139.1 - 5.5e-73 246.7 0.0 7.5e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 GAN09139.1 - 3.8e-40 136.6 0.0 7.6e-40 135.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAN09139.1 - 4.3e-33 114.4 0.0 1.1e-32 113.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 GAN09139.1 - 0.034 13.3 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase DUF3700 PF12481.8 GAN09139.1 - 0.038 13.4 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Aluminium induced protein AAA_lid_3 PF17862.1 GAN09139.1 - 0.19 11.6 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA+ lid domain Arm PF00514.23 GAN09140.1 - 3.2e-14 52.4 10.2 1.4e-08 34.5 0.1 7.1 8 1 0 8 8 8 3 Armadillo/beta-catenin-like repeat NDUFA12 PF05071.16 GAN09140.1 - 2.4e-08 34.7 0.7 6.4e-08 33.3 0.7 1.8 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 HEAT_EZ PF13513.6 GAN09140.1 - 0.068 13.7 0.4 1.5 9.4 0.2 3.1 3 1 1 4 4 4 0 HEAT-like repeat PMT_4TMC PF16192.5 GAN09140.1 - 1.6 8.3 5.1 0.27 10.8 0.8 1.8 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase EZH2_WD-Binding PF11616.8 GAN09140.1 - 9.1 6.5 9.6 0.8 9.9 1.7 2.9 3 0 0 3 3 3 0 WD repeat binding protein EZH2 SNF2_N PF00176.23 GAN09141.1 - 3.8e-66 223.2 0.0 7.9e-66 222.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN09141.1 - 7.6e-20 71.3 0.1 3.5e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_11 PF13086.6 GAN09141.1 - 0.02 14.7 0.1 0.02 14.7 0.1 4.3 4 0 0 4 4 4 0 AAA domain TFIIE_beta PF02186.15 GAN09141.1 - 0.12 12.7 0.3 28 5.1 0.0 2.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain FliS PF02561.14 GAN09141.1 - 0.99 9.7 4.2 1.8 8.8 0.8 2.6 2 0 0 2 2 2 0 Flagellar protein FliS DDE_3 PF13358.6 GAN09142.1 - 2.9e-14 53.1 0.0 3.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Malic_M PF03949.15 GAN09142.1 - 0.22 10.8 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain ADK PF00406.22 GAN09143.1 - 2.5e-60 203.0 0.0 3.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAN09143.1 - 5.9e-21 75.3 0.0 1.1e-20 74.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAN09143.1 - 1.3e-17 63.4 0.0 2.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAN09143.1 - 6.3e-05 23.5 0.0 0.00024 21.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAN09143.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 GAN09143.1 - 0.068 13.4 0.3 0.65 10.2 0.1 2.1 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 GAN09143.1 - 0.086 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Band_7 PF01145.25 GAN09144.1 - 7.4e-31 107.5 0.7 2.1e-30 106.1 0.2 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 GAN09144.1 - 5.4e-27 93.6 2.7 1.3e-26 92.4 2.7 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 META PF03724.16 GAN09144.1 - 0.1 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 META domain DUF484 PF04340.12 GAN09144.1 - 2.7 7.6 5.8 6.2 6.4 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF484 HLH PF00010.26 GAN09145.1 - 1.5e-12 47.3 2.9 3.4e-12 46.1 2.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhoU_div PF01865.16 GAN09145.1 - 0.0035 16.7 1.7 0.0051 16.2 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF47 Nha1_C PF08619.10 GAN09145.1 - 0.01 15.1 17.8 0.016 14.5 17.8 1.3 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Ribosomal_L37 PF08561.10 GAN09145.1 - 0.023 15.2 6.0 0.055 14.0 6.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 TFIIA PF03153.13 GAN09145.1 - 0.031 14.3 34.7 0.04 13.9 34.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0560 PF10577.9 GAN09145.1 - 0.035 12.6 21.8 0.044 12.3 21.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Polyoma_coat2 PF00761.20 GAN09145.1 - 0.71 9.5 4.9 1.2 8.8 4.9 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein DUF1754 PF08555.10 GAN09145.1 - 3.2 8.6 16.8 7.7 7.4 16.8 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FAM176 PF14851.6 GAN09145.1 - 9.2 5.9 10.7 18 4.9 10.7 1.5 1 0 0 1 1 1 0 FAM176 family IML1 PF12257.8 GAN09146.1 - 1.8e-117 391.5 0.0 1.4e-116 388.7 0.0 2.5 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 GAN09146.1 - 4.5e-19 68.3 0.1 1.1e-18 67.1 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DASH_Duo1 PF08651.10 GAN09147.1 - 0.054 13.3 0.3 0.054 13.3 0.3 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 GM_CSF PF01109.17 GAN09147.1 - 0.081 13.1 2.9 7.4 6.7 0.9 2.7 2 1 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor DnaJ PF00226.31 GAN09149.1 - 2.1e-08 34.2 0.2 0.0003 20.9 0.1 2.5 1 1 1 2 2 2 2 DnaJ domain DUF1704 PF08014.11 GAN09149.1 - 0.01 14.9 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) DUF4504 PF14953.6 GAN09151.1 - 2.7e-05 23.7 0.9 0.00025 20.5 0.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) Sel1 PF08238.12 GAN09152.1 - 1.1e-129 419.9 61.4 5.8e-10 39.5 0.2 15.1 15 0 0 15 15 15 15 Sel1 repeat Flu_M1_C PF08289.11 GAN09152.1 - 0.037 14.2 0.1 16 5.8 0.0 4.4 4 1 1 5 5 5 0 Influenza Matrix protein (M1) C-terminal domain TPR_17 PF13431.6 GAN09152.1 - 0.75 10.3 11.9 72 4.1 0.1 7.7 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN09152.1 - 2.6 8.9 20.3 84 4.1 0.1 9.4 11 1 0 11 11 11 0 Tetratricopeptide repeat DUF3920 PF13058.6 GAN09153.1 - 0.0079 16.4 0.4 0.013 15.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3920) Ribosomal_S24e PF01282.19 GAN09155.1 - 6.5e-36 122.1 0.1 6.5e-36 122.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S24e adh_short PF00106.25 GAN09156.1 - 2.4e-37 128.3 0.1 3.1e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN09156.1 - 1.4e-23 83.7 0.1 1.9e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN09156.1 - 1.2e-06 28.5 0.1 1.8e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN09156.1 - 0.0043 16.6 0.1 0.0068 15.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACT_7 PF13840.6 GAN09156.1 - 0.037 13.8 1.5 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 ACT domain 3HCDH_N PF02737.18 GAN09156.1 - 0.066 13.1 0.1 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF953 PF06110.11 GAN09157.1 - 5.7e-22 77.6 0.0 6.2e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 GAN09157.1 - 0.033 14.0 0.5 0.04 13.7 0.4 1.5 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 GAN09157.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like 3Beta_HSD PF01073.19 GAN09158.1 - 0.025 13.6 0.5 0.029 13.4 0.5 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cofilin_ADF PF00241.20 GAN09159.1 - 5.2e-27 94.1 0.5 5.8e-27 93.9 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UCH PF00443.29 GAN09160.1 - 2.7e-40 138.5 0.1 3.8e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAN09160.1 - 6.8e-13 48.8 0.8 1.4e-12 47.7 0.8 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAN09160.1 - 5.4e-11 42.7 0.4 6.8e-10 39.0 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ebola_NP PF05505.12 GAN09160.1 - 0.024 13.0 0.0 0.036 12.4 0.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein VPS13 PF16908.5 GAN09160.1 - 0.049 13.4 0.3 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal Forkhead PF00250.18 GAN09161.1 - 3.6e-38 129.7 1.1 1.3e-37 127.9 0.3 2.3 3 0 0 3 3 3 1 Forkhead domain FHA PF00498.26 GAN09161.1 - 3.1e-13 49.9 0.0 6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 GAN09161.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 FHA domain IML1 PF12257.8 GAN09161.1 - 0.1 11.7 0.4 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 PPV_E1_N PF00524.18 GAN09161.1 - 0.26 11.7 9.8 0.29 11.6 6.9 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain FAM176 PF14851.6 GAN09161.1 - 8.7 6.0 8.0 16 5.2 8.0 1.3 1 0 0 1 1 1 0 FAM176 family Glyco_hydro_38N PF01074.22 GAN09162.1 - 0.025 14.0 1.5 0.05 13.0 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 N-terminal domain T3SSipB PF16535.5 GAN09162.1 - 0.052 14.0 0.4 0.052 14.0 0.4 4.4 4 1 0 4 4 4 0 Type III cell invasion protein SipB Ph1570 PF09638.10 GAN09162.1 - 0.055 13.3 0.4 3.2 7.6 0.0 2.9 2 1 0 2 2 2 0 Ph1570 protein Baculo_PEP_C PF04513.12 GAN09162.1 - 0.32 11.0 0.1 0.32 11.0 0.1 3.9 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L6 PF00347.23 GAN09162.1 - 0.33 11.7 2.6 1.1 10.0 0.1 3.2 4 0 0 4 4 4 0 Ribosomal protein L6 TcpS PF17456.2 GAN09162.1 - 0.36 10.9 5.4 0.24 11.5 1.7 2.6 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S RIO1 PF01163.22 GAN09163.1 - 3.7e-46 157.1 0.0 3.7e-46 157.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 GAN09163.1 - 9.1e-36 121.9 0.1 3.5e-35 120.1 0.1 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 GAN09163.1 - 9.1e-10 38.9 0.0 0.00012 22.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAN09163.1 - 9e-07 28.4 0.0 0.033 13.6 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Drc1-Sld2 PF11719.8 GAN09163.1 - 0.032 13.8 32.1 0.043 13.4 32.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Glutaredoxin2_C PF04399.13 GAN09163.1 - 0.16 11.8 0.8 0.33 10.8 0.1 1.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DLIC PF05783.11 GAN09164.1 - 0.004 16.0 0.4 0.0062 15.4 0.4 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) DDE_Tnp_4 PF13359.6 GAN09167.1 - 3.3e-23 82.1 0.0 4.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 GAN09167.1 - 0.0033 17.1 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 GAN09167.1 - 0.011 15.3 0.1 0.075 12.7 0.1 2.0 1 1 0 1 1 1 0 Transposase DDE domain Ras PF00071.22 GAN09168.1 - 2e-07 30.8 0.1 9.2e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAN09168.1 - 0.00013 22.2 0.1 0.16 12.2 0.1 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Kinesin PF00225.23 GAN09170.1 - 5.3e-101 337.9 0.4 5.3e-101 337.9 0.4 2.5 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN09170.1 - 3.5e-23 82.2 5.5 4.8e-23 81.7 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding Ntox35 PF15534.6 GAN09170.1 - 2 8.9 5.9 20 5.7 0.2 3.1 3 0 0 3 3 3 0 Bacterial toxin 35 Peptidase_M1 PF01433.20 GAN09171.1 - 1.8e-46 158.4 0.0 2.9e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAN09171.1 - 3.2e-39 133.5 0.1 5.8e-39 132.7 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAN09171.1 - 3.5e-27 95.8 0.1 5.7e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Na_H_Exchanger PF00999.21 GAN09172.1 - 2e-60 204.6 24.3 2.7e-60 204.2 24.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CstA PF02554.14 GAN09172.1 - 0.0048 15.9 6.8 0.0048 15.9 6.8 2.5 1 1 1 2 2 2 1 Carbon starvation protein CstA YrhC PF14143.6 GAN09172.1 - 0.85 9.7 2.9 1.1 9.3 0.2 2.6 2 0 0 2 2 2 0 YrhC-like protein Phage_holin_3_3 PF16083.5 GAN09172.1 - 1.2 9.3 10.1 1.9 8.7 0.2 3.5 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III Na_Pi_cotrans PF02690.15 GAN09172.1 - 8.3 6.5 8.5 1.9 8.6 2.1 2.8 2 1 0 2 2 2 0 Na+/Pi-cotransporter Erf4 PF10256.9 GAN09173.1 - 0.002 18.3 1.2 0.0055 16.8 0.1 2.2 2 1 1 3 3 3 1 Golgin subfamily A member 7/ERF4 family ABC2_membrane_3 PF12698.7 GAN09173.1 - 0.0059 15.8 1.6 0.0086 15.2 1.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein CPBP PF02517.16 GAN09173.1 - 0.96 9.9 7.4 8.9 6.8 7.4 2.1 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease zf-MYND PF01753.18 GAN09174.1 - 4.3e-08 33.1 15.8 1e-07 31.9 15.8 1.7 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 GAN09174.1 - 0.48 11.6 35.1 5.7 8.1 0.3 3.3 2 1 0 2 2 2 0 ECL1/2/3 zinc binding proteins TAXi_N PF14543.6 GAN09175.1 - 0.87 9.8 4.9 0.87 9.8 2.6 2.0 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal PAP1 PF08601.10 GAN09176.1 - 3.8e-13 49.9 15.4 2.5e-12 47.2 0.1 2.1 1 1 1 2 2 2 2 Transcription factor PAP1 bZIP_1 PF00170.21 GAN09176.1 - 1.1e-07 31.8 19.0 7.2e-07 29.2 19.0 2.2 1 1 0 1 1 1 1 bZIP transcription factor PV-1 PF06637.11 GAN09176.1 - 0.011 14.6 0.6 0.011 14.6 0.6 1.7 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Jnk-SapK_ap_N PF09744.9 GAN09176.1 - 0.021 15.0 5.6 0.047 13.9 5.6 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TM1586_NiRdase PF14512.6 GAN09176.1 - 0.11 12.1 1.5 0.18 11.4 1.5 1.2 1 0 0 1 1 1 0 Putative TM nitroreductase bZIP_2 PF07716.15 GAN09176.1 - 0.6 10.2 18.1 1.3 9.1 17.2 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Secretin_N_2 PF07655.13 GAN09176.1 - 9.5 6.8 11.0 12 6.5 0.1 3.7 3 1 1 4 4 4 0 Secretin N-terminal domain Methyltransf_11 PF08241.12 GAN09177.1 - 1.2e-09 38.7 0.0 2.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN09177.1 - 1.8e-08 34.4 0.0 6.1e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN09177.1 - 1.1e-07 32.5 0.0 3.7e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN09177.1 - 8.2e-05 22.1 0.0 0.00034 20.0 0.0 2.0 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAN09177.1 - 0.002 18.0 0.0 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF3246 PF11596.8 GAN09177.1 - 0.087 12.2 2.6 0.16 11.4 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DER1 PF04511.15 GAN09178.1 - 4.6e-20 72.3 0.2 5.5e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 Der1-like family Lin-8 PF03353.15 GAN09178.1 - 0.11 12.0 1.7 0.14 11.7 1.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MSA-2c PF12238.8 GAN09178.1 - 1.2 9.1 9.4 1.6 8.7 9.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Inhibitor_I78 PF11720.8 GAN09180.1 - 2e-05 24.5 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 GAN09180.1 - 4.2e-05 24.1 0.5 5.6e-05 23.7 0.5 1.5 1 1 0 1 1 1 1 Potato inhibitor I family HECT PF00632.25 GAN09182.1 - 2.8e-74 250.4 0.0 4.9e-74 249.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 GAN09182.1 - 1.1e-13 51.2 0.4 4.1e-13 49.4 0.4 2.1 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A FA_hydroxylase PF04116.13 GAN09183.1 - 3.1e-19 69.6 19.3 3.1e-19 69.6 19.3 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ATP_bind_1 PF03029.17 GAN09183.1 - 0.0092 15.8 0.2 0.014 15.2 0.2 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TM2 PF05154.16 GAN09184.1 - 3.6e-15 56.0 3.3 3.6e-15 56.0 3.3 1.8 2 0 0 2 2 2 1 TM2 domain SLC3A2_N PF16028.5 GAN09184.1 - 0.066 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Velvet PF11754.8 GAN09185.1 - 1.7e-39 136.3 1.2 2.7e-39 135.6 1.2 1.3 1 0 0 1 1 1 1 Velvet factor Oxidored_FMN PF00724.20 GAN09187.1 - 7.4e-69 232.6 0.0 9.3e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 GAN09188.1 - 7e-36 123.9 31.5 1.3e-35 123.0 31.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAN09188.1 - 3.6e-09 36.4 5.7 7.5e-09 35.4 5.7 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PX PF00787.24 GAN09189.1 - 3e-22 78.7 0.6 8.6e-22 77.3 0.2 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 GAN09189.1 - 1.1e-09 38.2 3.5 0.00022 20.9 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like GCP_N_terminal PF17681.1 GAN09189.1 - 0.00049 19.8 0.1 0.00089 19.0 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal BAR_3_WASP_bdg PF10456.9 GAN09189.1 - 0.0081 15.6 3.6 0.12 11.8 0.1 2.3 2 0 0 2 2 2 2 WASP-binding domain of Sorting nexin protein Peptidase_C10 PF01640.17 GAN09189.1 - 0.01 16.2 0.9 0.023 15.0 0.2 1.8 1 1 1 2 2 2 0 Peptidase C10 family CysG_dimeriser PF10414.9 GAN09189.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region tRNA-synt_1c PF00749.21 GAN09189.1 - 0.53 9.1 3.8 0.42 9.4 0.7 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain BLOC1_2 PF10046.9 GAN09189.1 - 3 8.2 6.8 8.6 6.7 0.0 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ThiF PF00899.21 GAN09190.1 - 4.7e-32 111.3 0.0 7.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 GAN09190.1 - 1.3e-06 28.7 0.3 5.7e-06 26.6 0.3 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 GAN09190.1 - 0.0019 17.8 0.3 0.0043 16.7 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 GAN09190.1 - 0.0064 16.1 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 GAN09190.1 - 0.0082 15.5 0.4 0.02 14.2 0.4 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 GAN09190.1 - 0.033 14.3 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GAN09190.1 - 0.061 12.6 0.2 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain DDA1 PF10172.9 GAN09190.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase CLTH PF10607.9 GAN09191.1 - 4.6e-24 85.0 0.0 8.1e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 GAN09191.1 - 7.6e-23 80.9 0.4 1.5e-22 80.0 0.4 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 GAN09191.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 LisH Ribosomal_S10 PF00338.22 GAN09192.1 - 1.5e-32 111.7 0.0 2.5e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e OPT PF03169.15 GAN09193.1 - 2.2e-22 79.5 4.0 2.4e-22 79.3 4.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 GAN09194.1 - 2.4e-101 340.3 14.1 2.8e-101 340.1 14.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MacB_PCD PF12704.7 GAN09194.1 - 0.28 11.5 5.6 0.43 10.9 3.2 2.1 1 1 1 2 2 2 0 MacB-like periplasmic core domain Cadherin_C_2 PF16492.5 GAN09194.1 - 2.5 8.9 4.6 0.63 10.8 0.1 2.3 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Ribosomal_S9 PF00380.19 GAN09195.1 - 1.2e-31 109.8 0.1 1.3e-31 109.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 14-3-3 PF00244.20 GAN09196.1 - 3.8e-105 350.3 5.8 4.4e-105 350.1 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 GAN09196.1 - 0.58 10.7 0.1 0.58 10.7 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Gti1_Pac2 PF09729.9 GAN09198.1 - 1.7e-44 152.1 7.9 2.4e-34 119.0 0.2 3.2 2 1 1 3 3 3 2 Gti1/Pac2 family Ank_4 PF13637.6 GAN09199.1 - 4.7e-33 113.1 2.4 9.3e-14 51.6 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN09199.1 - 1.6e-30 105.6 1.7 5.3e-16 59.0 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN09199.1 - 7.3e-27 93.1 1.2 1.2e-08 35.1 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN09199.1 - 4.9e-21 72.6 1.3 0.00012 22.2 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 GAN09199.1 - 1.6e-15 57.0 15.4 1.6e-15 57.0 15.4 2.9 2 1 1 3 3 3 1 FYVE zinc finger Ank PF00023.30 GAN09199.1 - 5.7e-14 51.8 4.1 0.0032 17.8 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat zf-RING_2 PF13639.6 GAN09199.1 - 7.2e-08 32.6 4.5 7.2e-08 32.6 4.5 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN09199.1 - 0.00018 21.3 3.4 0.00018 21.3 3.4 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN09199.1 - 0.00028 20.6 6.6 0.00028 20.6 6.6 2.4 2 0 0 2 2 2 1 RING-like zinc finger Trm112p PF03966.16 GAN09199.1 - 0.0006 20.3 0.8 0.0018 18.8 0.1 2.2 2 0 0 2 2 2 1 Trm112p-like protein zf-rbx1 PF12678.7 GAN09199.1 - 0.022 15.0 5.5 0.022 15.0 5.5 3.2 2 2 0 2 2 2 0 RING-H2 zinc finger domain RNA_pol_Rpb1_1 PF04997.12 GAN09200.1 - 6.4e-116 387.0 0.0 1.2e-115 386.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAN09200.1 - 1.8e-106 355.5 0.4 3.2e-106 354.7 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAN09200.1 - 2.7e-76 255.4 0.0 7.1e-76 254.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 GAN09200.1 - 7.4e-67 224.9 0.5 7.4e-67 224.9 0.5 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 GAN09200.1 - 1.3e-51 174.7 0.0 4.4e-51 172.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 GAN09200.1 - 5e-49 165.7 5.3 1.1e-48 164.6 5.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 GAN09200.1 - 3.9e-39 132.9 0.7 1.1e-38 131.5 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 GAN09200.1 - 2.1e-14 53.0 358.1 0.019 15.3 5.8 17.5 5 2 18 26 26 26 24 RNA polymerase Rpb1 C-terminal repeat p450 PF00067.22 GAN09201.1 - 2.7e-38 131.9 0.0 5.6e-38 130.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF4602 PF15375.6 GAN09203.1 - 0.00011 22.5 14.2 0.00011 22.5 14.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4602) NOGCT PF08155.11 GAN09203.1 - 0.13 12.3 1.0 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 NOGCT (NUC087) domain DUF3300 PF11737.8 GAN09203.1 - 0.31 10.6 2.6 6.2 6.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) CPSase_L_D3 PF02787.19 GAN09203.1 - 4.3 7.7 8.7 0.91 9.9 0.1 3.1 3 1 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MFS_1 PF07690.16 GAN09204.1 - 6e-27 94.5 32.5 1.4e-26 93.3 32.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAN09204.1 - 0.00012 21.1 0.6 0.00012 21.1 0.6 2.5 2 1 0 3 3 3 1 MFS_1 like family FA_FANCE PF11510.8 GAN09205.1 - 9e-07 28.5 2.6 1.2e-05 24.8 0.9 2.1 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE RNA_lig_T4_1 PF09511.10 GAN09206.1 - 3.6e-73 246.1 0.8 6.8e-73 245.2 0.1 1.7 1 1 1 2 2 2 1 RNA ligase FRD2 PF03197.13 GAN09206.1 - 0.1 12.9 0.4 0.44 10.9 0.2 2.1 2 0 0 2 2 2 0 Bacteriophage FRD2 protein WD40 PF00400.32 GAN09207.1 - 1.1e-07 32.5 10.2 0.00021 22.0 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09207.1 - 3e-06 27.4 0.0 0.00047 20.4 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAN09207.1 - 0.0034 16.0 0.0 0.0061 15.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 GAN09207.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 GAN09208.1 - 1.9e-24 86.2 36.1 2.7e-24 85.8 36.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Baculo_ME53 PF06061.11 GAN09209.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Y_phosphatase3 PF13350.6 GAN09210.1 - 1.3e-55 188.9 0.0 1.9e-55 188.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 GAN09210.1 - 8.5e-05 21.9 0.5 0.0052 16.1 0.0 2.8 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Y_phosphatase PF00102.27 GAN09210.1 - 0.00054 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Abhydrolase_1 PF00561.20 GAN09210.1 - 0.0012 18.5 0.1 0.058 13.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2430 PF10353.9 GAN09210.1 - 0.0031 17.9 0.0 0.0088 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2430) DSPc PF00782.20 GAN09210.1 - 0.084 12.7 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Peptidase_S9 PF00326.21 GAN09210.1 - 0.098 12.1 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family LRR_4 PF12799.7 GAN09211.1 - 2.9e-08 33.9 0.3 0.0005 20.4 0.0 4.0 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAN09211.1 - 7.5e-08 31.8 7.7 0.13 12.4 0.0 4.9 5 0 0 5 5 5 3 Leucine Rich repeat F-box-like PF12937.7 GAN09211.1 - 0.00016 21.5 0.5 0.0006 19.7 0.5 2.1 1 0 0 1 1 1 1 F-box-like Med19 PF10278.9 GAN09211.1 - 0.034 14.1 1.2 0.061 13.3 1.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 LRR_1 PF00560.33 GAN09211.1 - 0.13 12.9 3.3 18 6.4 0.4 5.0 4 1 1 5 5 5 0 Leucine Rich Repeat NPM1-C PF16276.5 GAN09211.1 - 0.17 11.9 0.7 32 4.6 0.0 2.8 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain PUF PF00806.19 GAN09212.1 - 5.3e-68 221.1 14.1 1e-08 34.4 0.0 8.8 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 GAN09212.1 - 0.08 12.8 1.0 43 3.9 0.0 4.2 4 1 1 5 5 5 0 Single Cache domain 2 AIF_C PF14721.6 GAN09214.1 - 4.2e-48 163.0 0.5 9.9e-48 161.8 0.0 1.9 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 GAN09214.1 - 1.5e-46 159.0 0.7 2.1e-46 158.5 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN09214.1 - 2.2e-13 50.5 2.9 2.2e-11 44.1 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN09214.1 - 3.4e-10 39.7 3.7 5.3e-09 35.8 3.2 2.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAN09214.1 - 4e-07 29.5 0.1 4.9e-05 22.6 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAN09214.1 - 1.5e-06 27.2 0.5 0.035 12.8 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 GAN09214.1 - 2.2e-06 27.5 4.1 0.0043 16.7 0.2 3.7 2 2 2 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAN09214.1 - 5.1e-06 26.5 2.1 0.13 12.3 0.2 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 GAN09214.1 - 6.4e-06 25.7 2.7 9.9e-05 21.8 0.6 2.2 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 GAN09214.1 - 6.2e-05 22.2 1.0 0.23 10.5 0.0 3.3 2 2 1 3 3 3 2 Lycopene cyclase protein ThiF PF00899.21 GAN09214.1 - 0.088 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 GAN09214.1 - 0.15 10.9 1.5 16 4.2 0.1 2.9 2 1 1 3 3 3 0 Tryptophan halogenase vATP-synt_E PF01991.18 GAN09215.1 - 3.3e-60 202.9 12.5 3.9e-60 202.7 12.5 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Afaf PF15339.6 GAN09215.1 - 0.076 12.7 1.2 0.13 12.0 1.2 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor LRR_8 PF13855.6 GAN09216.1 - 3.4e-36 122.8 40.7 4.1e-11 42.5 10.2 7.8 6 1 2 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 GAN09216.1 - 9.8e-26 89.4 42.6 1.4e-05 25.3 0.4 8.5 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN09216.1 - 2.3e-06 27.4 41.7 0.38 11.5 0.2 12.0 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 GAN09216.1 - 1.5e-05 24.6 19.5 0.0031 17.1 2.9 4.4 1 1 2 4 4 4 4 Leucine-rich repeat PLDc PF00614.22 GAN09217.1 - 2.5e-18 65.4 1.8 1.8e-10 40.5 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAN09217.1 - 1.8e-16 60.2 0.0 5.1e-07 29.6 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain PH_12 PF16457.5 GAN09218.1 - 1.5 9.4 8.5 3.2 8.3 8.5 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain LRR_8 PF13855.6 GAN09219.1 - 1.8e-21 75.6 18.4 1.7e-10 40.5 2.1 3.4 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAN09219.1 - 8.3e-16 57.9 15.1 9.6e-06 25.9 0.1 4.3 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN09219.1 - 0.00014 22.0 12.9 25 5.9 0.0 6.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 GAN09219.1 - 0.0029 17.5 21.2 6.8 7.0 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich repeat Ribosomal_L9_C PF03948.14 GAN09220.1 - 5.1e-14 52.5 0.6 5.1e-14 52.5 0.6 1.9 3 0 0 3 3 3 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 GAN09220.1 - 1.3e-11 43.9 0.1 3e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Peptidase_S24 PF00717.23 GAN09221.1 - 8.9e-07 28.8 0.2 2.5e-06 27.4 0.2 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 GAN09221.1 - 0.0033 17.2 0.0 1 9.1 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 F-box-like PF12937.7 GAN09222.1 - 1.5e-06 28.0 0.4 5.7e-06 26.1 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN09222.1 - 0.01 15.7 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain SMC_N PF02463.19 GAN09223.1 - 3.4e-21 75.7 0.0 1.9e-20 73.3 0.0 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAN09223.1 - 1.5e-19 71.3 0.0 1.5e-19 71.3 0.0 7.4 3 3 2 6 6 6 1 AAA domain AAA_15 PF13175.6 GAN09223.1 - 5.3e-07 29.7 12.3 5.3e-07 29.7 12.3 5.0 3 2 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 GAN09223.1 - 0.00018 21.2 0.0 0.00051 19.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAN09223.1 - 0.00067 19.6 4.0 0.0058 16.5 0.2 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system YokU PF14122.6 GAN09223.1 - 0.1 12.6 0.7 0.42 10.6 0.7 2.1 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin AAA_27 PF13514.6 GAN09223.1 - 0.68 9.5 0.0 0.68 9.5 0.0 4.7 6 0 0 6 6 6 0 AAA domain MFS_1 PF07690.16 GAN09224.1 - 6.7e-35 120.6 43.9 5.3e-22 78.2 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN09224.1 - 1.5e-06 27.4 37.9 6e-05 22.1 37.9 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter CENP-B_dimeris PF09026.10 GAN09225.1 - 0.016 15.6 6.2 0.036 14.4 6.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Coprogen_oxidas PF01218.18 GAN09226.1 - 1e-129 431.5 0.0 1.2e-129 431.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase EI24 PF07264.11 GAN09227.1 - 0.00075 19.8 1.8 0.00075 19.8 1.8 2.0 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) MWFE PF15879.5 GAN09227.1 - 4.6 7.5 5.9 0.64 10.2 0.3 2.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DEAD PF00270.29 GAN09228.1 - 6e-42 143.4 0.0 1.6e-41 142.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN09228.1 - 9.2e-28 96.8 0.4 1e-26 93.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAN09228.1 - 0.0077 16.5 0.8 0.067 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran_CTD PF16326.5 GAN09228.1 - 0.13 12.5 13.2 0.72 10.1 13.2 2.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain IFT20 PF14931.6 GAN09228.1 - 0.5 10.5 10.9 5 7.3 4.3 3.8 4 0 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 F-box-like PF12937.7 GAN09229.1 - 7.8e-07 28.9 0.5 2.3e-06 27.4 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN09229.1 - 0.063 13.2 1.3 0.93 9.5 0.4 3.4 3 1 0 3 3 3 0 F-box domain Nucleoporin2 PF04096.14 GAN09230.1 - 1.3e-44 151.9 0.1 2e-44 151.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 GAN09230.1 - 0.00011 22.9 276.2 0.076 13.9 36.5 10.3 3 2 5 8 8 8 2 Nucleoporin FG repeat region mRNA_cap_enzyme PF01331.19 GAN09231.1 - 1.7e-52 178.1 0.0 3e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GAN09231.1 - 1.3e-30 106.2 0.0 2.2e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 GAN09231.1 - 8.3e-11 41.9 0.1 4.9e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 GAN09231.1 - 0.013 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 RNA ligase Peptidase_M24 PF00557.24 GAN09232.1 - 5.6e-42 143.8 0.0 8.8e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 GAN09232.1 - 0.23 11.5 9.3 0.33 11.0 9.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cdh1_DBD_1 PF18196.1 GAN09232.1 - 0.39 11.1 7.2 7.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 IHABP4_N PF16174.5 GAN09232.1 - 3.5 8.2 12.0 5.6 7.5 12.0 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal PIEZO PF15917.5 GAN09232.1 - 3.6 7.0 7.0 5.3 6.5 7.0 1.1 1 0 0 1 1 1 0 Piezo Ferrochelatase PF00762.19 GAN09233.1 - 2.2e-114 381.8 0.0 2.6e-114 381.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 GAN09233.1 - 0.0056 17.0 0.0 9.7 6.6 0.0 3.4 3 0 0 3 3 3 2 CbiX Ribosomal_L2_C PF03947.18 GAN09234.1 - 0.00011 22.5 0.1 0.00061 20.0 0.0 2.0 1 1 1 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Cas1_AcylT PF07779.12 GAN09235.1 - 2e-139 465.6 29.8 2.9e-139 465.0 29.8 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 GAN09235.1 - 3.2e-05 23.8 0.0 7.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF2663 PF10864.8 GAN09235.1 - 0.55 10.6 0.0 0.55 10.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2663) Sec10 PF07393.11 GAN09236.1 - 7.9e-196 652.6 2.2 7.9e-196 652.6 2.2 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec10 CEP63 PF17045.5 GAN09236.1 - 0.012 15.5 0.9 0.012 15.5 0.9 1.9 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa TEP1_N PF05386.11 GAN09236.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 TEP1 N-terminal domain MLD PF11647.8 GAN09236.1 - 0.044 14.0 0.0 2.9 8.3 0.0 2.8 2 0 0 2 2 2 0 Membrane Localization Domain Syntaxin-6_N PF09177.11 GAN09236.1 - 0.057 14.0 2.3 0.18 12.4 0.3 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal GIT1_C PF12205.8 GAN09236.1 - 0.1 12.7 0.2 0.1 12.7 0.2 2.9 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Occludin_ELL PF07303.13 GAN09236.1 - 0.38 11.5 4.8 0.98 10.2 0.0 3.5 3 1 1 4 4 4 0 Occludin homology domain DUF4407 PF14362.6 GAN09236.1 - 2.4 7.5 6.3 0.55 9.5 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Proteasome PF00227.26 GAN09237.1 - 8.1e-62 208.1 0.1 1e-61 207.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAN09237.1 - 7.4e-14 51.1 0.1 1.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF92 PF01940.16 GAN09238.1 - 1.7e-77 260.0 2.9 2e-77 259.8 2.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 PsaL PF02605.15 GAN09238.1 - 0.027 14.1 0.3 0.052 13.2 0.3 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI DUF2142 PF09913.9 GAN09238.1 - 0.038 12.9 0.6 0.059 12.2 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Chromo PF00385.24 GAN09239.1 - 6.5e-09 35.6 0.1 1.5e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3836 PF12930.7 GAN09239.1 - 0.91 9.3 5.1 0.51 10.1 1.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF3836) RGS PF00615.19 GAN09240.1 - 1.5e-05 25.3 0.5 7.9e-05 22.9 0.5 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain PTPlike_phytase PF14566.6 GAN09242.1 - 1.5e-138 457.3 0.0 3.8e-48 163.5 0.0 3.8 4 0 0 4 4 4 3 Inositol hexakisphosphate DSPc PF00782.20 GAN09242.1 - 6.5e-09 35.7 0.0 0.0089 15.8 0.0 3.8 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN09242.1 - 1.1e-06 28.4 0.0 0.041 13.4 0.0 3.4 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAN09242.1 - 0.00029 20.9 0.0 0.14 12.1 0.0 3.6 3 0 0 3 3 3 1 Tyrosine phosphatase family MAAL_C PF07476.11 GAN09242.1 - 0.036 13.2 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus ABC_membrane PF00664.23 GAN09243.1 - 1.1e-37 130.2 5.8 1.5e-37 129.7 5.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAN09243.1 - 2.6e-36 125.1 0.0 6.8e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAN09243.1 - 5.6e-05 23.6 0.0 0.00025 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAN09243.1 - 7.4e-05 22.3 0.1 0.0012 18.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 GAN09243.1 - 0.0011 19.4 0.0 0.025 15.0 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAN09243.1 - 0.0011 19.2 0.1 0.014 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAN09243.1 - 0.0053 16.8 0.0 0.18 11.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TOPRIM_C PF16898.5 GAN09243.1 - 0.022 15.0 0.1 0.055 13.7 0.1 1.7 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM AAA_21 PF13304.6 GAN09243.1 - 0.025 14.4 0.3 0.08 12.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAN09243.1 - 0.027 14.7 0.4 0.18 12.1 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 GAN09243.1 - 0.04 14.0 0.0 0.47 10.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 GAN09243.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 GAN09243.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 GAN09243.1 - 0.062 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 GAN09243.1 - 0.083 12.6 0.5 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 GAN09243.1 - 0.1 12.8 0.6 0.69 10.1 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 GAN09243.1 - 0.12 12.6 0.5 3 8.1 0.0 2.6 2 1 0 3 3 2 0 AAA domain AAA_23 PF13476.6 GAN09243.1 - 0.14 12.6 0.2 0.56 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SGL PF08450.12 GAN09244.1 - 0.0029 17.3 0.0 1.3 8.6 0.0 2.9 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 GAN09244.1 - 0.0047 17.7 1.4 8 7.5 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat UPF0370 PF13980.6 GAN09244.1 - 0.085 12.9 0.9 3.6 7.7 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Edc3_linker PF16598.5 GAN09244.1 - 8.4 7.1 10.2 0.49 11.1 1.3 2.7 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 MutS_V PF00488.21 GAN09245.1 - 1.4e-75 253.5 0.0 2.5e-75 252.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAN09245.1 - 5.2e-38 131.2 4.4 1.1e-37 130.1 4.4 1.6 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAN09245.1 - 1.4e-22 80.0 0.0 3.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAN09245.1 - 1.3e-12 48.1 0.0 3.4e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAN09245.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV NusG_II PF07009.11 GAN09245.1 - 0.039 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 NusG domain II AAA_29 PF13555.6 GAN09245.1 - 0.066 13.0 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zn_clus PF00172.18 GAN09246.1 - 5.4e-06 26.4 8.7 9.9e-06 25.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S64 PF08192.11 GAN09246.1 - 0.087 11.3 7.6 0.11 10.9 7.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF104 PF01954.16 GAN09246.1 - 0.18 12.3 0.1 0.38 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 Presenilin PF01080.17 GAN09246.1 - 0.33 9.7 12.6 0.49 9.1 12.6 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 GAN09246.1 - 0.6 8.6 9.6 0.73 8.3 9.6 1.1 1 0 0 1 1 1 0 Macoilin family CSG2 PF16965.5 GAN09246.1 - 1.3 7.9 5.5 1.9 7.3 5.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4175 PF13779.6 GAN09246.1 - 3.4 5.5 21.3 4.3 5.1 21.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ALMT PF11744.8 GAN09246.1 - 3.4 6.4 7.6 5 5.8 7.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LAP1C PF05609.12 GAN09246.1 - 4 6.4 19.6 5.6 5.9 19.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PAS PF00989.25 GAN09246.1 - 4.4 7.3 0.0 4.4 7.3 0.0 3.1 2 1 1 3 3 3 0 PAS fold Glyco_trans_2_3 PF13632.6 GAN09247.1 - 2.7e-15 56.8 0.1 2.7e-15 56.8 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 YMF19 PF02326.15 GAN09247.1 - 0.18 12.6 0.3 0.18 12.6 0.3 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 RSN1_7TM PF02714.15 GAN09248.1 - 2e-56 191.4 29.5 2e-56 191.4 29.5 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAN09248.1 - 2.8e-15 56.4 0.5 5.2e-13 49.0 0.1 3.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAN09248.1 - 1.8e-14 54.4 2.2 4.1e-14 53.2 2.2 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PyocinActivator PF11112.8 GAN09248.1 - 0.026 14.7 0.1 0.089 12.9 0.1 1.9 2 0 0 2 2 2 0 Pyocin activator protein PrtN Exonuc_VII_L PF02601.15 GAN09248.1 - 0.23 11.0 1.1 0.49 9.9 1.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DAO PF01266.24 GAN09249.1 - 1.6e-35 123.3 0.0 2e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAN09249.1 - 3.7e-05 23.1 0.0 6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN09249.1 - 0.00066 19.0 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 GAN09249.1 - 0.009 15.5 0.0 0.18 11.3 0.0 2.4 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 GAN09249.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 GAN09249.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAN09249.1 - 0.053 14.1 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAN09249.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GAN09249.1 - 0.22 10.8 0.1 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 GAN09250.1 - 5.7e-38 131.4 0.0 6.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN09250.1 - 7.9e-05 22.8 0.1 0.00019 21.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN09250.1 - 8.3e-05 22.0 0.1 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN09250.1 - 0.00019 21.9 0.4 0.00083 19.9 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 GAN09250.1 - 0.0003 20.3 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 GAN09250.1 - 0.00069 19.2 0.3 0.0026 17.4 0.2 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAN09250.1 - 0.00075 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAN09250.1 - 0.0018 17.6 0.3 0.0035 16.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GAN09250.1 - 0.0053 17.2 0.1 0.014 15.8 0.1 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.22 GAN09250.1 - 0.0089 15.1 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAN09250.1 - 0.0091 15.1 0.0 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 GAN09250.1 - 0.013 15.2 0.3 0.024 14.3 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 GAN09250.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_4 PF13439.6 GAN09250.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 2-Hacid_dh_C PF02826.19 GAN09250.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAN09250.1 - 0.16 12.0 0.5 2.4 8.2 0.1 2.5 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 GAN09250.1 - 0.23 10.1 0.1 0.38 9.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Aa_trans PF01490.18 GAN09251.1 - 1.7e-81 274.0 36.0 2.3e-81 273.6 36.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 GAN09251.1 - 0.048 13.7 0.4 0.38 10.8 0.4 2.6 1 0 0 1 1 1 0 Uncharacterized YmpT-like NARP1 PF12569.8 GAN09251.1 - 2.4 7.0 6.2 3.4 6.5 6.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 XRCC4 PF06632.12 GAN09251.1 - 2.4 6.9 7.1 1.4 7.7 4.4 1.8 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Androgen_recep PF02166.16 GAN09251.1 - 3.2 6.5 8.9 5 5.9 8.9 1.2 1 0 0 1 1 1 0 Androgen receptor DHQ_synthase PF01761.20 GAN09253.1 - 2.8e-93 311.9 0.0 4.4e-93 311.2 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 GAN09253.1 - 9.5e-45 153.6 0.0 1.6e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fe-ADH_2 PF13685.6 GAN09253.1 - 4e-07 30.0 0.7 1.4e-06 28.2 0.7 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase NdhM PF10664.9 GAN09253.1 - 0.021 15.1 0.0 0.07 13.4 0.0 1.9 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DPBB_1 PF03330.18 GAN09254.1 - 5.9e-08 32.9 0.0 1.4e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase Use1 PF09753.9 GAN09254.1 - 0.017 14.9 6.6 0.021 14.6 6.6 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 zinc_ribbon_9 PF14369.6 GAN09254.1 - 0.19 12.0 0.3 0.38 11.1 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon Zip PF02535.22 GAN09254.1 - 7.2 5.7 6.4 9.1 5.4 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GAN09254.1 - 9 4.9 6.1 11 4.7 6.1 1.2 1 0 0 1 1 1 0 Presenilin Ada3 PF10198.9 GAN09255.1 - 5.1e-32 110.8 4.0 5.1e-32 110.8 4.0 4.1 4 0 0 4 4 4 1 Histone acetyltransferases subunit 3 P21-Arc PF04062.14 GAN09256.1 - 1.3e-75 253.3 0.1 1.6e-75 253.0 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit MNSV_P7B PF06692.11 GAN09256.1 - 0.086 12.8 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein SET PF00856.28 GAN09257.1 - 0.0016 18.9 0.1 0.0039 17.6 0.1 1.6 1 1 0 1 1 1 1 SET domain zinc_ribbon_10 PF10058.9 GAN09258.1 - 5.8e-18 64.4 0.4 1e-17 63.6 0.4 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_9 PF14369.6 GAN09258.1 - 1.9 8.8 4.0 8.1 6.8 0.6 2.5 1 1 1 2 2 2 0 zinc-ribbon zf-RanBP PF00641.18 GAN09258.1 - 2.5 7.5 5.0 11 5.5 1.0 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Sel1 PF08238.12 GAN09260.1 - 2.2e-55 183.8 23.4 8.6e-08 32.6 0.4 7.9 7 1 0 7 7 7 7 Sel1 repeat Transpos_assoc PF13963.6 GAN09260.1 - 0.072 13.4 0.3 3.3 8.1 0.1 2.7 2 0 0 2 2 2 0 Transposase-associated domain Rgp1 PF08737.10 GAN09261.1 - 7.7e-97 325.1 2.7 1.7e-90 304.2 2.0 2.1 1 1 1 2 2 2 2 Rgp1 Arrestin_C PF02752.22 GAN09261.1 - 5.3e-05 23.7 0.1 0.064 13.7 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN09261.1 - 0.0096 16.0 0.3 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PH_11 PF15413.6 GAN09262.1 - 1.5 9.3 6.6 0.52 10.7 1.4 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain Pet100 PF09803.9 GAN09263.1 - 1.3e-24 86.5 0.1 1.5e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 Pet100 PHD PF00628.29 GAN09264.1 - 3.5e-09 36.4 8.5 3.5e-09 36.4 8.5 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 GAN09264.1 - 0.025 14.1 3.7 0.054 13.1 3.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 GAN09264.1 - 0.82 9.9 5.7 2 8.6 5.7 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain M20_dimer PF07687.14 GAN09265.1 - 4.1e-12 46.0 0.1 4.6e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAN09265.1 - 1.1e-07 31.8 0.1 1.8e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GTP_cyclohydroI PF01227.22 GAN09267.1 - 1e-76 256.4 0.5 1.2e-76 256.1 0.5 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 GAN09267.1 - 1.1e-05 25.5 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein F-box-like PF12937.7 GAN09268.1 - 0.0039 17.1 0.2 0.011 15.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like Complex1_LYR PF05347.15 GAN09269.1 - 2e-08 34.1 0.5 4e-08 33.2 0.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAN09269.1 - 3e-08 34.3 0.4 4e-08 33.9 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like MIX PF18529.1 GAN09269.1 - 0.062 13.0 0.1 0.073 12.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins TFIID_20kDa PF03847.13 GAN09269.1 - 0.12 12.9 0.3 0.28 11.7 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A RhoGEF PF00621.20 GAN09270.1 - 5e-34 118.1 8.4 5e-34 118.1 4.6 2.5 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 GAN09270.1 - 0.0005 20.5 0.1 0.0022 18.5 0.1 2.1 1 0 0 1 1 1 1 PH domain Caleosin PF05042.13 GAN09271.1 - 1.8e-48 164.7 0.1 2.7e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 Caleosin related protein ATPase_gene1 PF09527.10 GAN09271.1 - 0.21 11.8 2.5 0.36 11.0 2.5 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Ricin_B_lectin PF00652.22 GAN09272.1 - 8.9e-44 148.8 11.2 2.6e-06 27.7 0.1 13.4 10 4 2 12 12 12 9 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 GAN09272.1 - 3.9e-21 75.6 24.4 0.0038 17.9 0.1 13.1 11 1 1 12 12 12 6 Ricin-type beta-trefoil lectin domain-like cwf21 PF08312.12 GAN09272.1 - 0.011 15.8 0.2 8.8 6.6 0.0 3.6 2 0 0 2 2 2 0 cwf21 domain COMM_domain PF07258.14 GAN09272.1 - 0.047 13.8 2.2 0.16 12.1 0.1 3.2 2 0 0 2 2 2 0 COMM domain STPPase_N PF16891.5 GAN09272.1 - 0.19 12.2 5.3 21 5.7 0.0 4.4 4 0 0 4 4 4 0 Serine-threonine protein phosphatase N-terminal domain MADF_DNA_bdg PF10545.9 GAN09272.1 - 0.64 10.4 4.1 2.4 8.6 0.0 4.5 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Methyltransf_25 PF13649.6 GAN09273.1 - 6.5e-10 39.6 1.7 5.9e-07 30.1 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GAN09273.1 - 1.8e-09 37.6 2.6 4.6e-07 29.8 0.1 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAN09273.1 - 3.2e-09 37.3 1.2 5.2e-08 33.4 0.0 2.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN09273.1 - 1.3e-06 28.4 0.1 7.2e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN09273.1 - 5.4e-06 25.9 0.2 0.0003 20.2 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 GAN09273.1 - 0.00064 18.4 0.1 0.15 10.6 0.0 2.2 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 GAN09273.1 - 0.011 15.3 0.3 2.3 7.8 0.0 2.4 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 GAN09273.1 - 0.014 16.1 1.5 4.5 8.1 0.0 2.7 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_8 PF05148.15 GAN09273.1 - 0.018 14.9 0.2 0.086 12.7 0.2 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase SAP PF02037.27 GAN09274.1 - 9e-11 41.3 0.4 2.4e-10 39.9 0.2 1.9 2 0 0 2 2 2 1 SAP domain SUIM_assoc PF16619.5 GAN09274.1 - 4.5 7.4 21.4 4.6 7.4 0.4 5.2 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 SNARE PF05739.19 GAN09275.1 - 1.4e-11 44.2 0.3 3e-11 43.1 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GAN09275.1 - 0.0023 17.6 1.8 0.0023 17.6 1.8 3.2 2 1 1 3 3 3 1 Syntaxin DHR10 PF18595.1 GAN09275.1 - 0.0083 16.2 4.1 0.0083 16.2 4.1 3.0 2 1 1 3 3 3 1 Designed helical repeat protein 10 domain Syntaxin-5_N PF11416.8 GAN09275.1 - 0.021 14.1 0.0 0.055 12.7 0.0 1.8 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain APG17 PF04108.12 GAN09275.1 - 0.037 13.2 12.2 0.15 11.2 2.9 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 Allexi_40kDa PF05549.11 GAN09275.1 - 0.15 11.6 12.7 0.33 10.4 5.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3552 PF12072.8 GAN09275.1 - 0.18 11.2 13.3 0.18 11.2 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) zf-C4H2 PF10146.9 GAN09275.1 - 0.19 12.0 16.8 1.3 9.2 3.4 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4988 PF16378.5 GAN09275.1 - 0.4 10.3 7.9 0.38 10.4 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function MCU PF04678.13 GAN09275.1 - 0.64 10.1 3.3 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter MCPsignal PF00015.21 GAN09275.1 - 0.94 9.3 9.8 0.064 13.1 2.4 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 GAN09275.1 - 0.96 9.7 10.7 5.6 7.3 0.6 3.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 GAN09275.1 - 1 8.5 9.3 4.1 6.5 3.3 2.5 2 1 0 2 2 2 0 TMPIT-like protein Spectrin PF00435.21 GAN09275.1 - 1.2 9.7 11.1 0.21 12.1 1.6 2.9 2 1 1 3 3 3 0 Spectrin repeat DUF1664 PF07889.12 GAN09275.1 - 1.3 9.1 10.4 4.5 7.3 2.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SF-assemblin PF06705.11 GAN09275.1 - 1.8 7.8 18.1 0.17 11.2 3.2 2.4 2 1 0 2 2 2 0 SF-assemblin/beta giardin Vps53_N PF04100.12 GAN09275.1 - 1.8 7.4 11.9 0.17 10.8 2.1 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal AI-2E_transport PF01594.16 GAN09275.1 - 2.1 7.4 11.3 0.6 9.2 2.0 2.2 2 0 0 2 2 2 0 AI-2E family transporter Fungal_TACC PF12709.7 GAN09275.1 - 2.2 8.8 7.7 2.9 8.4 1.6 3.2 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Syntaxin-6_N PF09177.11 GAN09275.1 - 3.1 8.4 12.1 16 6.1 4.3 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF724 PF05266.14 GAN09275.1 - 3.8 7.3 12.6 7.8 6.3 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF16 PF01519.16 GAN09275.1 - 5.5 7.5 13.6 1.3 9.6 1.2 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 GAN09275.1 - 6.1 7.2 14.4 3.8 7.9 3.3 3.2 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Troponin PF00992.20 GAN09275.1 - 6.6 7.0 8.2 0.72 10.2 0.7 2.6 2 1 0 2 2 2 0 Troponin FlaC_arch PF05377.11 GAN09275.1 - 6.7 7.2 10.5 6 7.3 3.3 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) MHC2-interact PF09307.10 GAN09275.1 - 8.1 6.5 11.7 0.51 10.3 0.4 3.3 3 0 0 3 3 3 0 CLIP, MHC2 interacting SGT1 PF07093.11 GAN09276.1 - 1.5e-120 403.4 24.0 4.3e-107 359.0 0.1 2.9 1 1 1 2 2 2 2 SGT1 protein GSIII_N PF12437.8 GAN09277.1 - 3.7e-67 225.0 0.3 6.1e-67 224.3 0.3 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 GAN09277.1 - 8.7e-41 138.5 1.3 1.7e-40 137.5 1.3 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 GAN09277.1 - 6e-21 74.8 0.0 1.4e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF2070 PF09843.9 GAN09278.1 - 4.4 5.5 16.8 6.8 4.8 16.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PWI PF01480.17 GAN09279.1 - 4.6e-31 107.0 0.8 1.1e-30 105.7 0.1 2.0 2 0 0 2 2 2 1 PWI domain FUSC PF04632.12 GAN09279.1 - 0.047 12.2 0.8 0.057 12.0 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ketoacyl-synt PF00109.26 GAN09279.1 - 0.054 13.1 0.2 0.21 11.1 0.3 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Rotamase_3 PF13616.6 GAN09279.1 - 0.1 13.1 0.3 0.1 13.1 0.3 2.0 3 0 0 3 3 3 0 PPIC-type PPIASE domain KDZ PF18758.1 GAN09281.1 - 4.8e-34 117.9 1.8 1.2e-20 74.0 0.1 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 GAN09281.1 - 0.0028 17.8 0.2 0.0069 16.5 0.2 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF5039 PF16442.5 GAN09281.1 - 0.0068 16.0 2.4 0.16 11.5 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5039) F-box-like PF12937.7 GAN09282.1 - 8.1e-08 32.0 0.1 2.5e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN09282.1 - 3.4e-05 24.1 6.6 0.025 15.0 0.1 4.1 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN09282.1 - 0.0031 17.3 0.3 0.013 15.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain Myb_DNA-binding PF00249.31 GAN09283.1 - 4.3e-05 23.6 0.0 9.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain U-box PF04564.15 GAN09283.1 - 0.0027 17.8 0.0 0.0094 16.1 0.0 1.9 1 0 0 1 1 1 1 U-box domain Pro-kuma_activ PF09286.11 GAN09283.1 - 0.014 15.7 1.0 0.045 14.1 1.0 1.9 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain PBP1_TM PF14812.6 GAN09283.1 - 1.8 9.0 11.2 2.6 8.5 4.7 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.7 GAN09284.1 - 0.0004 20.2 1.3 0.0016 18.3 0.4 2.4 2 0 0 2 2 2 1 F-box-like Vac14_Fab1_bd PF12755.7 GAN09284.1 - 0.083 13.5 0.3 0.36 11.5 0.1 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region LRR_6 PF13516.6 GAN09284.1 - 0.17 12.0 20.0 7.6 6.9 0.2 7.1 7 0 0 7 7 7 0 Leucine Rich repeat Ribosomal_L30 PF00327.20 GAN09284.1 - 0.23 11.4 0.9 1.2 9.1 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein L30p/L7e LRR_4 PF12799.7 GAN09284.1 - 0.3 11.6 18.1 19 5.8 0.0 6.8 2 2 5 7 7 7 0 Leucine Rich repeats (2 copies) PS_Dcarbxylase PF02666.15 GAN09286.1 - 6.5e-59 198.9 0.0 1e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 GAN09286.1 - 5.5e-35 119.8 0.0 3.4e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain UBZ_FAAP20 PF15750.5 GAN09286.1 - 0.048 13.6 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger PepSY_2 PF13670.6 GAN09286.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SGT1 PF07093.11 GAN09286.1 - 1.1 7.6 8.7 1.8 6.9 8.7 1.2 1 0 0 1 1 1 0 SGT1 protein Trypsin PF00089.26 GAN09287.1 - 6.4e-23 81.7 0.0 8.6e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAN09287.1 - 3.3e-06 28.1 0.0 7e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain Sacchrp_dh_C PF16653.5 GAN09288.1 - 2.6e-83 280.2 0.0 4.8e-83 279.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 GAN09288.1 - 1.4e-30 106.3 0.0 4e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 GAN09288.1 - 9.2e-23 80.9 0.2 1.7e-22 80.0 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAN09288.1 - 6.7e-06 26.2 0.1 2.3e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 GAN09288.1 - 8.7e-05 21.9 0.1 0.0014 18.0 0.0 2.6 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 GAN09288.1 - 8.7e-05 22.5 0.3 0.00017 21.5 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 GAN09288.1 - 0.0013 18.9 0.2 0.0025 17.9 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAN09288.1 - 0.0013 19.2 0.2 0.0076 16.7 0.1 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAN09288.1 - 0.0051 17.2 0.2 0.011 16.1 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_3 PF03447.16 GAN09288.1 - 0.066 13.9 0.5 0.14 12.8 0.5 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain HAUS6_N PF14661.6 GAN09289.1 - 2.1e-10 40.6 0.0 6.9e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus MCR PF18509.1 GAN09290.1 - 0.95 9.1 4.4 0.39 10.3 1.0 2.0 2 0 0 2 2 2 0 Magnetochrome domain GRIP PF01465.20 GAN09291.1 - 4.3e-17 61.7 0.4 1.5e-16 60.0 0.4 2.0 1 0 0 1 1 1 1 GRIP domain KASH_CCD PF14662.6 GAN09291.1 - 0.001 18.9 37.0 0.001 18.9 37.0 9.6 1 1 7 8 8 8 1 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 GAN09291.1 - 0.0058 17.2 24.7 0.0058 17.2 24.7 12.4 1 1 10 12 12 12 4 Apg6 coiled-coil region CENP-Q PF13094.6 GAN09291.1 - 0.011 15.9 10.0 0.011 15.9 10.0 11.4 1 1 9 11 11 11 0 CENP-Q, a CENPA-CAD centromere complex subunit PXA PF02194.15 GAN09292.1 - 2e-42 145.2 3.0 2e-42 145.2 3.0 3.0 4 0 0 4 4 4 1 PXA domain Nexin_C PF08628.12 GAN09292.1 - 5.8e-08 33.3 0.9 3.9e-07 30.6 0.0 2.8 4 0 0 4 4 4 1 Sorting nexin C terminal Far-17a_AIG1 PF04750.14 GAN09292.1 - 0.00029 20.2 24.2 0.00065 19.1 24.2 1.5 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF4834 PF16118.5 GAN09292.1 - 0.058 14.4 0.4 0.058 14.4 0.4 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) SieB PF14163.6 GAN09292.1 - 0.64 9.5 4.9 0.21 11.1 0.3 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B SLY PF12485.8 GAN09292.1 - 2.6 8.8 10.3 4.6 7.9 0.9 2.3 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein Ints3 PF10189.9 GAN09293.1 - 1.3e-79 266.6 2.1 5.4e-79 264.6 0.3 2.4 2 0 0 2 2 2 1 Integrator complex subunit 3 BAMBI PF06211.12 GAN09293.1 - 0.023 14.9 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Ribosomal_S27 PF01599.19 GAN09294.1 - 4.7e-27 93.9 2.5 1.1e-26 92.8 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 GAN09294.1 - 1.2e-17 63.4 0.0 2.2e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAN09294.1 - 6.6e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 GAN09294.1 - 0.016 15.4 0.5 0.029 14.6 0.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 GAN09294.1 - 0.027 14.5 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-like domain ThrE PF06738.12 GAN09296.1 - 2.5e-43 148.2 28.1 2.6e-41 141.6 6.5 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter PPI_Ypi1 PF07491.11 GAN09296.1 - 8.9e-24 83.1 5.0 8.9e-24 83.1 5.0 2.1 2 1 0 2 2 2 1 Protein phosphatase inhibitor ThrE_2 PF12821.7 GAN09296.1 - 3.1e-10 40.3 34.8 1.1e-09 38.6 15.4 3.1 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE YL1 PF05764.13 GAN09296.1 - 0.0044 17.2 1.0 0.0062 16.7 1.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SR-25 PF10500.9 GAN09296.1 - 0.0053 16.4 5.0 0.0053 16.4 5.0 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.10 GAN09296.1 - 0.01 15.6 1.7 0.01 15.6 1.7 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFMR_assoc PF16596.5 GAN09296.1 - 0.035 14.6 2.8 0.14 12.6 2.8 2.0 1 0 0 1 1 1 0 Disordered region downstream of MFMR CDC45 PF02724.14 GAN09296.1 - 0.056 11.7 3.1 0.078 11.3 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 GAN09296.1 - 6.7 6.4 10.2 0.6 9.8 5.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF962 PF06127.11 GAN09298.1 - 1.8e-31 108.1 0.1 2e-31 107.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Tecti-min-caps PF09300.10 GAN09298.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Tectiviridae, minor capsid Pkinase PF00069.25 GAN09299.1 - 7.4e-26 91.1 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09299.1 - 2.1e-13 50.1 0.0 4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1582 PF07621.11 GAN09300.1 - 0.28 11.2 4.5 3.1 7.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) Homoserine_dh PF00742.19 GAN09301.1 - 5.8e-50 169.6 0.0 9.4e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAN09301.1 - 1.4e-20 74.1 0.0 2.6e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 GAN09301.1 - 0.0031 18.3 0.0 0.013 16.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 GAN09301.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ras PF00071.22 GAN09302.1 - 3.9e-55 185.9 0.0 4.6e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN09302.1 - 1.1e-23 83.7 0.0 1.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN09302.1 - 1.1e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN09302.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN09302.1 - 0.006 16.0 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAN09302.1 - 0.024 14.1 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAN09302.1 - 0.052 13.9 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 GAN09302.1 - 0.054 13.2 0.1 0.33 10.7 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAN09302.1 - 0.056 13.3 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 GAN09302.1 - 0.084 12.0 0.0 0.2 10.8 0.0 1.9 1 1 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 GAN09302.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 GAN09303.1 - 8.2e-58 192.2 0.3 6.5e-20 70.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN09303.1 - 7.6e-12 44.9 0.0 0.00015 21.6 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GAN09303.1 - 1.4e-11 44.0 0.1 7.1e-06 25.6 0.0 3.2 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN09303.1 - 4.2e-08 33.2 0.5 0.099 12.8 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 GAN09303.1 - 1.6e-05 25.0 0.4 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 RRM-like domain SET_assoc PF11767.8 GAN09303.1 - 8.8e-05 22.1 0.2 0.11 12.2 0.1 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 GAN09303.1 - 0.0083 16.1 0.5 3.3 7.8 0.0 3.3 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 GAN09303.1 - 0.099 12.3 0.2 18 5.1 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 GAN09303.1 - 0.22 11.6 1.2 7.1 6.8 0.1 3.2 3 1 0 3 3 3 0 Limkain b1 PHM7_cyt PF14703.6 GAN09303.1 - 0.34 11.1 0.1 0.34 11.1 0.1 4.0 5 0 0 5 5 3 0 Cytosolic domain of 10TM putative phosphate transporter CITED PF04487.12 GAN09303.1 - 9.4 6.2 14.9 23 5.0 14.9 1.6 1 0 0 1 1 1 0 CITED ANAPC4_WD40 PF12894.7 GAN09304.1 - 3.9e-11 43.1 0.2 0.00028 21.1 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN09304.1 - 1.1e-08 35.6 10.3 9.3e-06 26.3 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 GAN09304.1 - 1.6e-05 24.9 0.4 0.1 12.5 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A CC2-LZ PF16516.5 GAN09304.1 - 0.032 14.6 3.5 0.068 13.5 3.5 1.6 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 GAN09304.1 - 0.071 12.0 4.2 0.12 11.2 4.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-Q PF13094.6 GAN09304.1 - 0.12 12.6 4.4 0.28 11.4 4.4 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.9 GAN09304.1 - 0.37 9.8 5.6 0.63 9.1 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PspA_IM30 PF04012.12 GAN09304.1 - 0.58 9.7 8.8 0.98 9.0 8.8 1.3 1 0 0 1 1 1 0 PspA/IM30 family OTCace PF00185.24 GAN09305.1 - 0.058 13.5 2.0 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF919 PF06034.11 GAN09305.1 - 0.11 12.3 4.5 1 9.2 0.4 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) FAM76 PF16046.5 GAN09305.1 - 0.14 11.5 3.8 0.2 11.0 3.8 1.2 1 0 0 1 1 1 0 FAM76 protein ABC2_membrane PF01061.24 GAN09306.1 - 9.9e-83 276.7 64.7 3.5e-43 147.5 24.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAN09306.1 - 1.9e-34 119.1 0.0 6.9e-19 68.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAN09306.1 - 6.3e-29 99.7 8.1 8.4e-22 76.9 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAN09306.1 - 1.2e-13 51.4 0.1 2.6e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAN09306.1 - 3.2e-09 36.4 49.3 2.4e-05 23.6 13.4 3.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 GAN09306.1 - 1.5e-05 25.5 0.0 0.0017 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 GAN09306.1 - 5.7e-05 23.1 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAN09306.1 - 0.00019 21.4 0.1 0.0041 17.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 GAN09306.1 - 0.0021 17.8 0.2 0.011 15.5 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAN09306.1 - 0.0065 16.1 0.2 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GAN09306.1 - 0.041 13.2 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_18 PF13238.6 GAN09306.1 - 0.045 14.3 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAN09306.1 - 0.054 13.7 0.0 0.8 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 GAN09306.1 - 0.058 13.7 0.0 0.68 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAN09306.1 - 0.14 12.7 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAN09306.1 - 0.14 11.9 0.3 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAN09306.1 - 0.23 11.4 0.5 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Oxidored_molyb PF00174.19 GAN09307.1 - 3e-49 166.9 0.0 5.1e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAN09307.1 - 8e-30 103.7 1.8 1.3e-29 103.0 1.8 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Phosphoesterase PF04185.14 GAN09307.1 - 0.027 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoesterase family Transmemb_17 PF09799.9 GAN09309.1 - 3.5 8.2 26.0 0.039 14.5 8.3 3.8 3 1 0 3 3 3 0 Predicted membrane protein DUF2183 PF09949.9 GAN09310.1 - 3.5e-33 113.9 0.2 1.2e-32 112.2 0.2 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Acetyltransf_1 PF00583.25 GAN09311.1 - 3.4e-18 66.0 0.0 4.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN09311.1 - 6.9e-11 42.2 0.0 7.9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN09311.1 - 1.1e-10 41.7 0.0 1.7e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN09311.1 - 8.8e-08 32.0 0.1 1.4e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAN09311.1 - 0.0021 18.1 0.0 0.0042 17.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAN09311.1 - 0.0028 18.3 0.0 0.0033 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAN09311.1 - 0.006 16.7 0.1 0.0077 16.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAN09311.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RhoGAP PF00620.27 GAN09312.1 - 5e-37 127.1 0.0 1.3e-36 125.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MAP65_ASE1 PF03999.12 GAN09313.1 - 1.1e-67 229.1 29.1 1.1e-67 229.1 29.1 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Sulfatase_C PF14707.6 GAN09313.1 - 0.063 14.0 1.7 1.2 9.8 0.1 3.0 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase ZnuA PF01297.17 GAN09313.1 - 0.37 10.1 4.4 0.82 9.0 0.3 2.5 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic Cyt-b5 PF00173.28 GAN09314.1 - 7e-24 83.8 0.1 8.8e-24 83.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ELL PF10390.9 GAN09315.1 - 4.8e-11 42.7 5.0 1.3e-10 41.3 5.0 1.7 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Phage_holin_3_6 PF07332.11 GAN09316.1 - 0.22 11.6 0.4 0.3 11.1 0.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III dsRBD2 PF17842.1 GAN09317.1 - 0.063 13.5 2.1 0.067 13.4 0.1 1.8 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Presenilin PF01080.17 GAN09317.1 - 0.73 8.5 0.0 0.73 8.5 0.0 2.2 2 1 0 2 2 2 0 Presenilin Maf1 PF09174.10 GAN09319.1 - 0.26 11.4 2.2 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 Maf1 regulator Gln-synt_C PF00120.24 GAN09320.1 - 1.4e-17 63.8 0.0 1.3e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GAN09320.1 - 4.1e-12 45.6 0.0 6.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Ntox3 PF15536.6 GAN09320.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 3 O-FucT PF10250.9 GAN09321.1 - 0.012 15.3 0.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase AAA-ATPase_like PF09820.9 GAN09321.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Predicted AAA-ATPase Binary_toxB PF03495.14 GAN09321.1 - 0.096 12.9 0.1 0.85 9.8 0.0 2.4 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Sel_put PF04328.13 GAN09321.1 - 0.2 11.7 0.1 0.48 10.5 0.1 1.6 1 0 0 1 1 1 0 Selenoprotein, putative RabGAP-TBC PF00566.18 GAN09322.1 - 1.3e-54 185.1 0.2 1.3e-54 185.1 0.2 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 GAN09322.1 - 0.042 14.0 11.8 0.023 14.8 4.9 3.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 GAN09322.1 - 0.057 14.0 15.1 0.053 14.0 2.8 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region DMPK_coil PF08826.10 GAN09322.1 - 1.1 9.4 20.4 0.064 13.4 1.9 3.6 4 0 0 4 4 4 0 DMPK coiled coil domain like YabA PF06156.13 GAN09322.1 - 2.2 9.0 11.1 15 6.3 1.6 3.1 2 0 0 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 GAN09322.1 - 5.4 7.4 8.3 4.8 7.6 0.5 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family NosD PF05048.13 GAN09323.1 - 0.055 12.7 1.0 0.063 12.5 1.0 1.0 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Pkinase PF00069.25 GAN09324.1 - 1.1e-69 234.7 0.0 1.9e-69 234.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09324.1 - 9.3e-35 120.2 0.0 1.6e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN09324.1 - 2.1e-07 30.6 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN09324.1 - 0.00029 20.3 0.2 0.00063 19.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAN09324.1 - 0.0066 15.4 0.3 0.0066 15.4 0.3 2.1 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAN09324.1 - 0.016 15.2 0.6 0.028 14.4 0.6 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAN09324.1 - 0.088 11.8 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Myosin_head PF00063.21 GAN09325.1 - 1.4e-245 816.7 2.0 1.4e-245 816.7 2.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 GAN09325.1 - 0.18 11.7 0.2 0.39 10.6 0.2 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain IQ PF00612.27 GAN09325.1 - 0.24 11.3 2.3 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 GAN09325.1 - 0.48 10.7 0.0 0.48 10.7 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAN09325.1 - 0.59 10.5 0.0 0.59 10.5 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain ATG16 PF08614.11 GAN09325.1 - 1 9.5 53.7 0.24 11.6 21.5 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Pex14_N PF04695.13 GAN09326.1 - 0.17 12.5 23.0 0.15 12.7 2.3 3.0 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 GAN09326.1 - 1.1 8.2 16.0 0.53 9.2 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DivIC PF04977.15 GAN09326.1 - 5.1 6.9 15.0 7.8 6.3 5.5 2.3 2 0 0 2 2 2 0 Septum formation initiator Dynamin_M PF01031.20 GAN09327.1 - 3e-104 348.3 0.1 3e-104 348.3 0.1 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 GAN09327.1 - 3.1e-56 190.0 0.0 8.3e-56 188.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAN09327.1 - 4.6e-30 103.6 5.8 4.6e-30 103.6 5.8 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAN09327.1 - 8.7e-05 22.6 0.4 0.0004 20.4 0.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF778 PF05608.12 GAN09327.1 - 0.029 14.7 0.1 0.061 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) NPH3 PF03000.14 GAN09327.1 - 0.061 13.0 0.6 0.18 11.4 0.2 1.9 2 0 0 2 2 2 0 NPH3 family FeoB_N PF02421.18 GAN09327.1 - 0.08 12.5 0.2 13 5.3 0.1 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 GAN09327.1 - 0.14 12.5 0.1 0.86 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Sec7_N PF12783.7 GAN09327.1 - 0.33 10.8 5.0 2.7 7.9 0.0 3.2 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AAA_15 PF13175.6 GAN09327.1 - 0.58 9.8 8.0 5.5 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain DUF755 PF05501.11 GAN09327.1 - 1.3 9.3 8.6 1.4 9.2 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) GAS2 PF02187.17 GAN09329.1 - 2.6e-11 43.4 0.0 8.8e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain TnpV PF14198.6 GAN09329.1 - 1.6 8.7 6.0 1.9 8.5 0.1 4.0 5 0 0 5 5 5 0 Transposon-encoded protein TnpV Csm2_III-A PF03750.13 GAN09329.1 - 2.7 8.9 5.7 2.1e+02 2.8 0.1 4.8 4 0 0 4 4 4 0 Csm2 Type III-A CitMHS PF03600.16 GAN09330.1 - 6.9e-15 55.0 5.5 6.9e-15 55.0 5.5 2.3 1 1 1 2 2 2 1 Citrate transporter ArsB PF02040.15 GAN09330.1 - 4.6e-14 52.6 9.8 1.1e-07 31.5 1.4 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein RE_NgoFVII PF09565.10 GAN09330.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease UPF0225 PF17775.1 GAN09331.1 - 0.056 14.3 1.3 0.12 13.3 1.3 1.5 1 0 0 1 1 1 0 UPF0225 domain PSCyt3 PF07627.11 GAN09331.1 - 0.16 12.2 0.8 7.1 7.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) DUF3519 PF12033.8 GAN09331.1 - 1.2 9.5 8.8 5.4 7.5 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3519) Mak16 PF04874.14 GAN09331.1 - 2.2 8.9 9.4 3.7 8.2 9.4 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region CYSTM PF12734.7 GAN09332.1 - 7.4e-05 23.0 65.4 3.7e+02 1.5 65.4 4.4 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 GAN09332.1 - 0.18 12.5 8.3 0.19 12.4 8.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_transf_49 PF13896.6 GAN09333.1 - 1.2e-23 84.1 2.8 8.1e-19 68.1 0.0 2.5 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan DUF702 PF05142.12 GAN09333.1 - 2.5 8.6 5.1 4.6 7.7 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Velvet PF11754.8 GAN09334.1 - 1.6e-56 192.1 5.5 9.8e-28 97.8 0.1 2.6 2 1 1 3 3 3 2 Velvet factor tRNA-synt_2b PF00587.25 GAN09335.1 - 4.1e-36 124.6 0.0 8.1e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAN09335.1 - 4.9e-19 68.3 0.6 9.7e-19 67.3 0.6 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 GAN09335.1 - 2.7e-14 53.0 0.0 6.2e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 GAN09335.1 - 2.9e-12 46.5 0.0 7.7e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 TGS domain Velvet PF11754.8 GAN09336.1 - 8.1e-63 212.7 8.4 8.4e-62 209.3 0.6 2.9 2 1 0 2 2 2 1 Velvet factor DUF4805 PF16063.5 GAN09336.1 - 9.7e-05 21.8 2.5 0.00014 21.3 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4805) SEEEED PF14797.6 GAN09336.1 - 0.01 16.0 11.0 0.017 15.3 11.0 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex SR-25 PF10500.9 GAN09336.1 - 0.024 14.3 11.4 0.04 13.5 11.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein START PF01852.19 GAN09337.1 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 START domain RabGAP-TBC PF00566.18 GAN09338.1 - 3.4e-52 177.2 0.1 3.4e-52 177.2 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain KASH_CCD PF14662.6 GAN09338.1 - 0.09 12.6 35.2 0.017 14.9 13.1 3.6 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH RVT_3 PF13456.6 GAN09338.1 - 4.1 7.2 4.7 73 3.2 0.1 3.5 3 0 0 3 3 3 0 Reverse transcriptase-like Sel1 PF08238.12 GAN09339.1 - 9.6e-41 137.3 20.1 2.6e-08 34.3 1.6 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 GAN09339.1 - 0.0022 18.5 1.8 0.15 12.8 0.2 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN09339.1 - 0.08 13.6 17.7 0.24 12.1 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN09339.1 - 0.47 10.4 0.1 0.47 10.4 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN09339.1 - 1.1 9.7 5.9 15 6.1 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAN09339.1 - 1.5 9.1 5.4 1.7 8.9 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 GAN09340.1 - 2.9e-57 194.2 43.8 4e-57 193.7 43.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_2 PF07992.14 GAN09341.1 - 8.6e-51 172.9 0.3 1e-50 172.7 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN09341.1 - 9.6e-21 74.3 0.5 6.6e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN09341.1 - 4.5e-18 65.6 0.5 5e-16 59.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAN09341.1 - 3.9e-07 29.5 3.6 0.0049 16.0 0.1 4.0 3 2 1 4 4 4 3 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAN09341.1 - 8.1e-07 28.6 1.3 0.069 12.4 0.1 3.0 2 1 1 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 GAN09341.1 - 5.6e-05 23.5 0.0 0.01 16.2 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 GAN09341.1 - 6.2e-05 22.3 0.0 0.0015 17.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAN09341.1 - 0.00011 21.5 4.1 0.012 14.7 0.1 3.5 3 1 0 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.6 GAN09341.1 - 0.00015 21.9 0.3 0.046 13.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAN09341.1 - 0.00017 21.1 0.8 0.041 13.2 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 GAN09341.1 - 0.00029 20.5 0.3 1.3 8.5 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAN09341.1 - 0.0011 18.2 0.1 0.12 11.4 0.0 3.2 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAN09341.1 - 0.005 15.6 1.8 0.071 11.8 0.2 2.8 4 0 0 4 4 4 1 HI0933-like protein Shikimate_DH PF01488.20 GAN09341.1 - 0.022 14.8 0.0 6.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 GAN09341.1 - 0.037 13.6 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Trp_halogenase PF04820.14 GAN09341.1 - 0.064 12.1 0.2 0.74 8.6 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 GAN09341.1 - 0.15 11.7 0.6 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ABC_membrane PF00664.23 GAN09342.1 - 7.6e-88 294.7 36.7 8.4e-46 156.8 9.6 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN09342.1 - 2e-51 174.1 0.0 8.2e-28 97.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 GAN09342.1 - 3.4e-11 43.0 0.0 6e-05 22.6 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 GAN09342.1 - 6.6e-09 35.6 1.0 6.6e-09 35.6 1.0 2.2 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region MMR_HSR1 PF01926.23 GAN09342.1 - 3.4e-06 27.1 2.8 0.008 16.2 0.3 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN09342.1 - 6.1e-06 26.2 0.1 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAN09342.1 - 0.00016 22.1 0.9 0.076 13.4 0.4 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAN09342.1 - 0.00032 20.4 3.6 0.063 13.0 0.2 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAN09342.1 - 0.00064 19.6 2.4 0.48 10.2 0.0 3.7 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 GAN09342.1 - 0.024 14.7 3.9 0.036 14.1 0.4 2.4 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 GAN09342.1 - 0.041 13.6 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 GAN09342.1 - 0.048 14.1 0.4 5.1 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAN09342.1 - 0.061 13.4 4.9 2.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 GAN09342.1 - 0.084 12.4 0.1 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAN09342.1 - 0.12 12.6 3.8 5.4 7.3 0.3 3.4 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 GAN09342.1 - 0.21 11.8 0.6 40 4.4 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CsbD PF05532.12 GAN09343.1 - 0.0037 17.1 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 CsbD-like Iso_dh PF00180.20 GAN09344.1 - 3.3e-123 411.3 0.0 3.7e-123 411.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IlvN PF07991.12 GAN09345.1 - 5.9e-45 152.8 0.0 1e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 GAN09345.1 - 1.2e-42 145.6 0.0 9.6e-42 142.7 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 GAN09345.1 - 0.0059 17.2 0.1 0.046 14.3 0.0 2.4 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAN09345.1 - 0.017 15.3 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 GAN09345.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TPP_enzyme_N PF02776.18 GAN09346.1 - 2.8e-56 189.8 0.0 6e-56 188.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAN09346.1 - 5.2e-52 175.7 0.8 2.2e-50 170.4 0.4 3.2 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAN09346.1 - 4.1e-40 136.7 0.1 1.1e-39 135.3 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Glyco_trans_4_2 PF13477.6 GAN09346.1 - 0.13 12.3 0.0 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like AAA_18 PF13238.6 GAN09347.1 - 9.8e-28 97.3 0.7 1.1e-27 97.2 0.1 1.3 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 GAN09347.1 - 3.3e-10 40.5 0.3 1e-09 38.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 GAN09347.1 - 1.2e-06 28.7 0.1 9.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 GAN09347.1 - 7.6e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA PF00004.29 GAN09347.1 - 0.00014 22.3 0.8 0.00024 21.5 0.3 1.7 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAN09347.1 - 0.0004 20.6 0.2 0.0076 16.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAN09347.1 - 0.00055 20.2 1.3 0.00075 19.8 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN09347.1 - 0.00092 19.6 0.0 0.00097 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 GAN09347.1 - 0.0019 18.0 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 GAN09347.1 - 0.0038 16.5 0.1 0.038 13.3 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 GAN09347.1 - 0.0043 17.3 0.2 0.0073 16.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN09347.1 - 0.0051 17.2 0.9 0.0094 16.3 0.7 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAN09347.1 - 0.0069 16.4 0.3 0.026 14.5 0.1 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAN09347.1 - 0.0087 15.8 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAN09347.1 - 0.016 14.9 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAN09347.1 - 0.017 14.2 0.2 0.026 13.6 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein dNK PF01712.19 GAN09347.1 - 0.018 14.9 1.9 3.8 7.3 0.2 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase tRNA_lig_kinase PF08303.11 GAN09347.1 - 0.024 14.7 0.3 0.79 9.8 0.3 2.2 1 1 0 1 1 1 0 tRNA ligase kinase domain ATPase PF06745.13 GAN09347.1 - 0.044 13.1 0.5 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 KaiC KTI12 PF08433.10 GAN09347.1 - 0.047 13.1 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 GAN09347.1 - 0.047 13.0 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAN09347.1 - 0.052 13.9 0.2 0.16 12.4 0.0 1.9 2 1 0 2 2 2 0 RNA helicase ResIII PF04851.15 GAN09347.1 - 0.074 13.1 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 GAN09347.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 GAN09347.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.8 1 1 0 1 1 1 0 Shikimate kinase IstB_IS21 PF01695.17 GAN09347.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 GAN09347.1 - 0.11 12.5 0.1 0.21 11.6 0.0 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF853 PF05872.12 GAN09347.1 - 0.15 10.6 0.2 0.24 10.0 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CoaE PF01121.20 GAN09347.1 - 0.16 11.7 0.3 4.4 7.0 0.1 2.4 1 1 0 2 2 2 0 Dephospho-CoA kinase Mur_ligase_M PF08245.12 GAN09347.1 - 0.21 11.6 2.0 0.25 11.3 2.0 1.6 1 1 0 1 1 1 0 Mur ligase middle domain Complex1_LYR PF05347.15 GAN09348.1 - 6.4e-05 22.9 2.6 0.00011 22.2 0.6 2.5 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAN09348.1 - 0.048 14.4 2.4 0.055 14.2 0.7 2.1 2 1 0 2 2 2 0 Complex1_LYR-like RasGAP_C PF03836.15 GAN09348.1 - 0.088 12.9 2.5 0.14 12.3 2.5 1.5 1 1 0 1 1 1 0 RasGAP C-terminus PriCT_2 PF08707.11 GAN09348.1 - 0.12 12.8 0.0 17 5.8 0.0 2.5 3 0 0 3 3 3 0 Primase C terminal 2 (PriCT-2) Vps26 PF03643.15 GAN09349.1 - 9.1e-128 425.0 6.9 1.1e-127 424.8 6.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAN09349.1 - 0.024 14.7 0.8 0.67 10.0 0.1 3.0 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN09349.1 - 0.058 13.9 0.5 1.1 9.7 0.1 2.8 2 2 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain AMP-binding PF00501.28 GAN09350.1 - 7.3e-73 245.6 0.0 9.3e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN09350.1 - 8.2e-14 52.3 0.0 2.2e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ASFV_L11L PF05293.11 GAN09350.1 - 0.11 12.8 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein AMP-binding PF00501.28 GAN09351.1 - 1.1e-81 274.6 0.2 1.5e-81 274.2 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN09351.1 - 5.1e-15 56.2 0.0 9.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TMEM135_C_rich PF15982.5 GAN09354.1 - 7.7e-11 42.7 4.1 1.4e-10 41.9 1.0 2.3 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 GAN09354.1 - 3.5e-10 40.2 1.4 2.1e-07 31.3 0.3 2.8 3 0 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Oxidored_FMN PF00724.20 GAN09354.1 - 3.1e-08 33.3 0.0 0.0013 18.1 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family EF-hand_4 PF12763.7 GAN09355.1 - 0.035 14.1 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 GAN09356.1 - 1.6e-24 85.7 16.9 7.2e-05 23.5 1.6 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 GAN09356.1 - 5.3e-07 28.7 8.1 0.33 9.5 0.0 5.1 1 1 4 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAN09356.1 - 1.2e-06 28.7 0.3 0.057 13.7 0.1 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAN09356.1 - 1e-05 25.9 0.0 5.9 7.5 0.0 4.8 5 0 0 5 5 5 2 PQQ-like domain Nucleoporin_N PF08801.11 GAN09356.1 - 0.028 13.2 0.2 1.6 7.4 0.0 2.6 1 1 0 2 2 2 0 Nup133 N terminal like SGL PF08450.12 GAN09356.1 - 0.081 12.5 0.8 2.9 7.4 0.0 2.6 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Tetraspanin PF00335.20 GAN09357.1 - 0.043 13.5 12.1 0.32 10.7 12.1 2.0 1 1 0 1 1 1 0 Tetraspanin family Phage_holin_3_6 PF07332.11 GAN09357.1 - 0.16 12.0 9.3 1.2 9.2 4.9 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Tmpp129 PF10272.9 GAN09357.1 - 0.24 10.6 2.3 0.3 10.3 2.3 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF2207 PF09972.9 GAN09357.1 - 0.66 8.7 3.3 4 6.1 4.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2981 PF11200.8 GAN09357.1 - 2.5 7.8 6.5 2 8.1 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DUF4282 PF14110.6 GAN09357.1 - 3.1 8.6 13.4 2.7 8.8 10.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) HemY_N PF07219.13 GAN09357.1 - 6.7 7.0 5.6 12 6.1 0.4 2.8 2 1 1 3 3 3 0 HemY protein N-terminus TMEM70 PF06979.12 GAN09358.1 - 1.1e-05 25.8 2.9 0.00021 21.7 2.9 2.1 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Trs65 PF12735.7 GAN09359.1 - 1.2e-62 212.1 4.6 1.3e-62 212.1 0.0 2.6 1 1 1 2 2 2 1 TRAPP trafficking subunit Trs65 Steroid_dh PF02544.16 GAN09360.1 - 3.1e-21 75.9 0.9 6.6e-21 74.9 0.4 1.9 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 GAN09360.1 - 0.0025 18.2 0.1 0.0025 18.2 0.1 2.7 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAN09360.1 - 0.0091 15.5 0.7 0.023 14.2 0.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 GAN09360.1 - 0.3 11.5 3.6 0.42 11.1 0.1 2.5 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family GATA PF00320.27 GAN09361.1 - 1.2e-30 104.8 19.7 1.3e-15 56.7 5.5 2.8 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN09361.1 - 1.8e-07 30.6 6.8 0.00041 19.8 0.5 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 GAN09361.1 - 0.00041 20.5 7.6 0.12 12.6 0.4 2.9 2 1 1 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 GAN09361.1 - 0.0028 17.7 6.2 0.61 10.2 0.1 3.1 3 0 0 3 3 2 2 Zinc ribbon domain zf-RRN7 PF11781.8 GAN09361.1 - 0.027 14.2 5.9 0.21 11.3 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 GAN09361.1 - 0.27 11.6 8.8 0.48 10.8 0.4 2.9 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase PBP1_TM PF14812.6 GAN09361.1 - 0.46 10.9 4.5 1.1 9.7 4.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DZR PF12773.7 GAN09361.1 - 0.47 10.5 16.4 3.2 7.8 2.3 3.4 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 GAN09361.1 - 2.5 8.1 12.3 0.57 10.1 1.0 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 GAN09361.1 - 3.5 7.2 14.1 3.3 7.3 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain RP-C_C PF11800.8 GAN09361.1 - 4.5 7.3 8.3 1.4 9.0 1.1 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF2318 PF10080.9 GAN09361.1 - 8.5 6.6 9.6 39 4.4 0.2 3.2 2 2 0 2 2 2 0 Predicted membrane protein (DUF2318) Arm PF00514.23 GAN09362.1 - 1.6e-86 282.0 15.6 1.6e-14 53.3 0.0 9.3 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 GAN09362.1 - 1.5e-23 82.1 2.6 4.9e-23 80.4 2.6 2.0 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 GAN09362.1 - 1.9e-23 82.7 3.3 1.9e-23 82.7 3.3 3.4 4 0 0 4 4 3 1 Importin beta binding domain HEAT_EZ PF13513.6 GAN09362.1 - 1.3e-16 60.7 0.2 3.4e-06 27.4 0.0 5.9 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 GAN09362.1 - 5.4e-16 58.8 0.0 1.8e-07 31.4 0.0 5.1 1 1 6 7 7 7 3 HEAT repeats HEAT PF02985.22 GAN09362.1 - 1.3e-15 56.1 0.8 0.003 17.7 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 GAN09362.1 - 2.6e-06 27.1 0.0 0.039 13.4 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 GAN09362.1 - 3.5e-06 25.9 0.0 2.4e-05 23.1 0.0 2.3 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 GAN09362.1 - 0.0025 17.9 0.0 10 6.2 0.0 4.1 3 1 0 3 3 3 1 V-ATPase subunit H DUF3361 PF11841.8 GAN09362.1 - 0.012 15.5 0.0 3.8 7.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Cnd1 PF12717.7 GAN09362.1 - 0.03 14.4 0.0 3.2 7.8 0.0 3.3 1 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 GAN09362.1 - 0.044 14.0 0.4 2.2 8.6 0.0 3.4 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 GAN09362.1 - 0.1 13.3 0.4 11 7.1 0.0 3.5 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat ATP-synt_C PF00137.21 GAN09363.1 - 5.2e-26 90.8 29.1 9.2e-15 54.7 9.6 2.8 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.24 GAN09363.1 - 0.00011 21.8 0.2 0.00011 21.8 0.2 2.6 2 1 0 3 3 3 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2632 PF10943.8 GAN09363.1 - 0.044 13.4 0.2 0.044 13.4 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2632) G0-G1_switch_2 PF15103.6 GAN09363.1 - 1.1 9.7 2.7 1.4 9.4 0.5 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Glyoxalase PF00903.25 GAN09364.1 - 2.4e-20 73.0 0.1 2.9e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAN09364.1 - 2.4e-08 34.2 0.0 4.9e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAN09364.1 - 6.1e-06 27.0 0.0 3.3e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 GAN09364.1 - 0.00085 19.2 0.1 1.6 8.7 0.0 2.5 2 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 GAN09364.1 - 0.0035 17.5 0.0 0.31 11.1 0.0 2.3 2 1 0 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.6 GAN09364.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal DNA_pol_B PF00136.21 GAN09365.1 - 3.1e-101 339.4 0.0 5.3e-101 338.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAN09365.1 - 1.1e-19 70.7 4.3 4.8e-09 35.8 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAN09365.1 - 1.7e-13 50.8 11.3 1.7e-13 50.8 11.3 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF3330 PF11809.8 GAN09365.1 - 0.048 13.7 0.2 0.25 11.4 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Chordopox_RPO7 PF05864.12 GAN09365.1 - 0.77 10.1 3.7 1.4 9.2 1.6 2.5 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-CCHC PF00098.23 GAN09366.1 - 9e-42 139.3 48.1 8e-09 35.2 1.9 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 GAN09366.1 - 1.1e-07 31.5 24.9 0.078 12.7 0.5 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 GAN09366.1 - 4.5e-06 26.5 31.0 0.16 12.0 2.7 5.1 2 2 3 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 GAN09366.1 - 2.3e-05 24.0 27.7 0.1 12.3 0.8 5.2 4 1 1 5 5 5 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GAN09366.1 - 0.01 15.6 38.5 0.45 10.4 1.4 5.6 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_6 PF15288.6 GAN09366.1 - 0.2 11.5 31.9 0.91 9.4 0.3 5.2 5 0 0 5 5 5 0 Zinc knuckle TRAF6_Z2 PF18048.1 GAN09366.1 - 0.51 10.5 22.4 0.82 9.8 0.4 5.5 6 1 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 SpoIIE PF07228.12 GAN09367.1 - 5.9e-11 42.7 0.0 1.1e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAN09367.1 - 2.3e-10 40.5 0.1 0.00031 20.5 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAN09367.1 - 3.6e-06 26.8 0.0 7.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C UDPG_MGDP_dh_N PF03721.14 GAN09368.1 - 2.7e-64 216.2 0.1 6.2e-64 215.0 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 GAN09368.1 - 1.3e-35 122.0 1.0 1.8e-34 118.3 0.4 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 GAN09368.1 - 8.3e-30 102.9 0.0 1.7e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain OTCace PF00185.24 GAN09368.1 - 0.0022 18.1 0.2 0.096 12.8 0.1 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ldh_1_N PF00056.23 GAN09368.1 - 0.0022 18.1 0.2 1.6 8.8 0.2 2.9 2 1 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAN09368.1 - 0.0029 17.8 0.1 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 GAN09368.1 - 0.021 14.8 0.2 1.8 8.5 0.0 2.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 GAN09368.1 - 0.034 14.0 0.4 0.45 10.4 0.0 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA-ATPase_like PF09820.9 GAN09368.1 - 0.048 13.1 1.1 0.089 12.2 1.1 1.3 1 0 0 1 1 1 0 Predicted AAA-ATPase Sacchrp_dh_NADP PF03435.18 GAN09368.1 - 0.097 12.9 0.1 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain zf-LITAF-like PF10601.9 GAN09369.1 - 0.0026 18.0 0.2 0.0089 16.3 0.0 2.0 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain DUF2789 PF10982.8 GAN09369.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) RseA_C PF03873.13 GAN09369.1 - 0.1 12.9 2.9 0.11 12.8 0.2 2.4 2 1 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain FH2 PF02181.23 GAN09370.1 - 1e-61 209.2 11.2 2.2e-59 201.5 11.2 2.5 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAN09370.1 - 4e-35 121.1 0.0 4.7e-34 117.6 0.0 2.6 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAN09370.1 - 1.6e-27 96.4 4.3 1.7e-27 96.3 0.4 2.9 2 1 0 2 2 2 1 Diaphanous FH3 Domain 5_3_exonuc PF01367.20 GAN09370.1 - 0.39 11.3 2.6 1.2 9.8 0.2 3.0 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Myb_DNA-bind_6 PF13921.6 GAN09372.1 - 0.00037 20.7 0.4 0.00095 19.4 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN09372.1 - 0.006 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PPTA PF01239.22 GAN09373.1 - 1.4e-40 135.8 19.0 1.2e-08 34.4 0.0 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Caleosin PF05042.13 GAN09373.1 - 0.0091 15.9 1.4 0.76 9.7 0.4 2.5 2 0 0 2 2 2 2 Caleosin related protein TPR_17 PF13431.6 GAN09373.1 - 0.087 13.2 1.8 6.8 7.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat GATase PF00117.28 GAN09374.1 - 2.7e-12 46.9 0.0 3.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.16 GAN09374.1 - 1.7e-07 30.5 0.2 6.3e-07 28.6 0.2 1.8 1 1 0 1 1 1 1 Homoserine O-succinyltransferase DJ-1_PfpI PF01965.24 GAN09374.1 - 3e-05 23.9 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 GAN09374.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 GAN09374.1 - 0.00063 19.6 0.6 0.006 16.4 0.6 2.3 2 1 0 2 2 2 1 Peptidase C26 CutC PF03932.14 GAN09374.1 - 0.039 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 CutC family ThiJ_like PF17124.5 GAN09374.1 - 0.054 13.2 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like Glu-tRNAGln PF02686.15 GAN09374.1 - 0.16 12.3 0.2 23 5.4 0.0 2.6 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DSHCT PF08148.12 GAN09375.1 - 2.4e-52 176.9 0.1 6.2e-52 175.6 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 GAN09375.1 - 7.2e-40 135.9 0.1 1.3e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 GAN09375.1 - 1.4e-27 97.3 0.1 2.4e-27 96.5 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 GAN09375.1 - 3.6e-17 62.7 0.0 8.6e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN09375.1 - 2.3e-06 27.9 0.0 1.1e-05 25.7 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain RhoGAP PF00620.27 GAN09377.1 - 1e-37 129.3 0.9 4.7e-37 127.2 1.1 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 GAN09378.1 - 1.6e-16 60.7 0.5 5.3e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 GAN09378.1 - 5.3e-07 30.0 2.6 7.3e-07 29.6 0.2 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 GAN09378.1 - 0.00017 21.8 2.3 0.00028 21.1 0.8 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 GAN09378.1 - 0.033 14.5 0.2 0.33 11.3 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Ploopntkinase1 PF18748.1 GAN09378.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 CtaG_Cox11 PF04442.14 GAN09379.1 - 3.7e-60 202.3 0.1 5.6e-60 201.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 eIF-5a PF01287.20 GAN09380.1 - 1.1e-24 86.3 0.1 1.7e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GAN09380.1 - 0.0081 16.2 0.2 0.015 15.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain RhoGEF PF00621.20 GAN09381.1 - 1.4e-13 51.5 0.1 1.4e-13 51.5 0.1 2.6 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.18 GAN09381.1 - 3.7e-10 39.9 8.4 3.8e-10 39.8 5.2 2.2 2 0 0 2 2 2 1 BAR domain SH3_2 PF07653.17 GAN09381.1 - 0.00044 19.9 0.0 0.00086 18.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain EBA-175_VI PF11556.8 GAN09382.1 - 0.045 14.1 0.6 0.072 13.4 0.6 1.3 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 zf-C2H2 PF00096.26 GAN09383.1 - 1.8e-08 34.4 8.5 9.5e-05 22.6 2.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN09383.1 - 4.2e-06 26.9 1.0 4.2e-06 26.9 1.0 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN09383.1 - 0.0036 18.0 6.8 0.3 12.0 1.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger NUDIX PF00293.28 GAN09383.1 - 0.012 15.6 0.1 0.23 11.5 0.0 2.7 2 1 0 2 2 2 0 NUDIX domain zf-C2H2_8 PF15909.5 GAN09383.1 - 0.036 14.4 0.6 0.036 14.4 0.6 2.6 3 0 0 3 3 3 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAN09383.1 - 4.7 7.9 8.6 0.51 11.0 0.1 3.4 2 2 2 4 4 4 0 FOXP coiled-coil domain Cnd1 PF12717.7 GAN09384.1 - 1.1e-52 178.4 12.8 7.7e-52 175.6 2.0 3.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 GAN09384.1 - 1.1e-44 152.2 0.1 5.7e-44 149.9 0.1 2.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 GAN09384.1 - 7.8e-10 39.0 0.1 9.8e-05 22.7 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 GAN09384.1 - 1.4e-08 34.3 0.1 0.33 11.3 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 GAN09384.1 - 8.3e-05 21.3 13.8 0.00015 20.5 0.4 3.7 3 1 0 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 GAN09384.1 - 0.00012 22.3 1.9 0.14 12.3 0.0 3.8 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 GAN09384.1 - 0.00017 22.0 0.4 9.4 6.9 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd3 PF12719.7 GAN09384.1 - 0.00045 19.5 1.8 0.00045 19.5 1.8 3.7 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Arm_2 PF04826.13 GAN09384.1 - 0.0071 15.8 3.0 0.0097 15.4 0.3 2.3 2 0 0 2 2 2 1 Armadillo-like FANCI_S2 PF14676.6 GAN09384.1 - 0.017 15.5 0.6 1 9.7 0.0 4.0 3 1 0 3 3 3 0 FANCI solenoid 2 zf-C2H2_2 PF12756.7 GAN09385.1 - 1.4e-32 112.0 11.8 8e-27 93.5 1.2 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAN09385.1 - 6.6e-10 39.0 19.7 7.3e-08 32.5 3.3 4.3 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAN09385.1 - 3e-06 27.4 2.3 3e-06 27.4 2.3 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAN09385.1 - 7.9e-05 23.2 13.8 0.03 15.2 0.4 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger AKAP95 PF04988.12 GAN09385.1 - 0.0013 19.0 1.4 1.1 9.5 0.2 2.7 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) UAE_UbL PF14732.6 GAN09385.1 - 0.14 12.7 0.3 1.4 9.5 0.1 2.4 1 1 1 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain zf-C2H2 PF00096.26 GAN09385.1 - 0.29 11.7 18.5 2.5 8.7 1.0 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 GAN09385.1 - 1.3 9.2 8.5 8.9 6.4 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Tubulin-binding PF00418.19 GAN09387.1 - 7.1e-88 288.2 49.3 3.3e-11 43.0 1.0 9.7 9 0 0 9 9 9 8 Tau and MAP protein, tubulin-binding repeat HrcA_DNA-bdg PF03444.15 GAN09387.1 - 0.0054 16.4 7.1 1.6 8.4 0.0 5.3 5 0 0 5 5 5 2 Winged helix-turn-helix transcription repressor, HrcA DNA-binding AOC_like PF18678.1 GAN09387.1 - 0.024 14.2 3.3 4 7.0 0.0 3.8 3 1 0 4 4 4 0 Allene oxide cyclase barrel like domain ATP-synt_ab PF00006.25 GAN09388.1 - 2.2e-68 230.1 0.0 3.2e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAN09388.1 - 2.9e-13 50.1 0.4 8.9e-13 48.6 0.5 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 GAN09388.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF3533 PF12051.8 GAN09388.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Glyco_transf_15 PF01793.16 GAN09389.1 - 4.3e-65 220.1 7.4 5.4e-65 219.8 7.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Tubulin PF00091.25 GAN09390.1 - 7e-68 228.7 0.0 1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAN09390.1 - 1.5e-49 167.3 0.0 2.5e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAN09390.1 - 0.00041 20.1 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Homeodomain PF00046.29 GAN09391.1 - 7.3e-21 73.8 2.1 7.3e-21 73.8 2.1 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 GAN09391.1 - 0.012 15.5 0.2 0.012 15.5 0.2 3.7 4 0 0 4 4 4 0 Homeobox KN domain CAP_N PF01213.19 GAN09391.1 - 3.9 6.9 18.4 0.2 11.1 5.9 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Arrestin_N PF00339.29 GAN09392.1 - 6e-10 39.3 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Kelch_2 PF07646.15 GAN09393.1 - 1.8e-06 27.7 4.9 0.8 9.8 0.1 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 GAN09393.1 - 1.5e-05 25.1 8.9 0.14 12.5 0.2 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 GAN09393.1 - 2.3e-05 24.6 5.0 0.00042 20.5 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 GAN09393.1 - 2.6e-05 24.1 6.0 0.34 10.9 0.1 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN09393.1 - 3.4e-05 23.3 17.4 0.0002 20.8 0.9 5.3 5 0 0 5 5 5 3 Kelch motif ASC PF00858.24 GAN09393.1 - 0.00063 18.8 4.4 0.052 12.5 0.1 2.7 2 1 0 3 3 3 2 Amiloride-sensitive sodium channel Kelch_5 PF13854.6 GAN09393.1 - 0.0013 18.6 13.5 0.0067 16.4 1.3 3.9 4 0 0 4 4 4 2 Kelch motif Helitron_like_N PF14214.6 GAN09394.1 - 7.3e-12 45.9 0.0 1.3e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-C2H2_10 PF16588.5 GAN09394.1 - 1.8 8.4 9.4 1.2 8.9 6.5 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger Zn_ribbon_recom PF13408.6 GAN09394.1 - 2 9.0 6.6 4 8.0 0.8 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Peptidase_C12 PF01088.21 GAN09395.1 - 4.7e-47 160.5 0.0 5.5e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Homeodomain PF00046.29 GAN09396.1 - 4.5e-19 68.0 1.6 9.1e-19 67.1 1.6 1.6 1 0 0 1 1 1 1 Homeodomain PCI PF01399.27 GAN09397.1 - 4e-11 43.4 0.7 3.8e-10 40.2 0.1 2.7 2 0 0 2 2 2 1 PCI domain NUDIX PF00293.28 GAN09398.1 - 2.6e-11 43.7 0.1 3.7e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Response_reg PF00072.24 GAN09399.1 - 1.1e-20 73.9 0.2 6.6e-14 52.0 0.1 2.8 2 0 0 2 2 2 2 Response regulator receiver domain Lzipper-MIP1 PF14389.6 GAN09400.1 - 0.13 12.6 4.4 0.29 11.4 2.4 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Ogr_Delta PF04606.12 GAN09400.1 - 0.34 10.9 2.0 1.6 8.7 2.0 2.2 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger LCE6A PF15858.5 GAN09400.1 - 8 7.3 15.9 0.2 12.4 3.0 3.5 3 0 0 3 3 3 0 Late cornified envelope protein 6A family zf-RING_2 PF13639.6 GAN09401.1 - 1.9e-13 50.5 5.1 3.1e-13 49.8 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN09401.1 - 2.9e-11 43.0 4.7 4.8e-11 42.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN09401.1 - 4.8e-10 39.6 3.9 1.1e-09 38.4 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAN09401.1 - 1.7e-09 37.4 4.4 3e-09 36.6 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN09401.1 - 3.1e-09 36.4 2.4 5.7e-09 35.6 2.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GAN09401.1 - 3.2e-08 33.4 3.6 5.3e-08 32.7 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAN09401.1 - 8.8e-06 25.7 2.3 2e-05 24.5 2.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAN09401.1 - 9.4e-06 25.4 2.7 1.6e-05 24.7 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN09401.1 - 4.4e-05 23.5 1.4 8.4e-05 22.6 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAN09401.1 - 0.0044 16.8 4.2 0.0078 16.0 4.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 GAN09401.1 - 0.0044 16.9 4.5 0.0091 15.8 4.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GAN09401.1 - 0.0053 16.3 3.3 0.0097 15.5 3.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_5 PF17121.5 GAN09401.1 - 0.011 15.5 1.7 0.022 14.7 1.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAN09401.1 - 0.025 14.7 6.4 0.053 13.6 6.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 GAN09401.1 - 0.048 13.8 2.7 0.18 12.0 2.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 GAN09401.1 - 0.077 12.8 1.0 0.18 11.7 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.11 GAN09401.1 - 0.22 11.6 1.4 0.41 10.8 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING-like PF08746.11 GAN09401.1 - 0.31 11.4 6.0 0.69 10.3 6.0 1.6 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 GAN09401.1 - 0.9 9.5 6.2 1.8 8.5 6.2 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 GAN09401.1 - 7.4 6.6 8.4 5.3 7.1 6.4 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Ank_2 PF12796.7 GAN09402.1 - 1.4e-38 131.3 1.2 1.6e-20 73.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN09402.1 - 2.1e-38 130.2 6.8 4.7e-13 49.4 0.0 4.5 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAN09402.1 - 4.7e-34 116.0 2.0 2.1e-09 37.4 0.2 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAN09402.1 - 1.6e-31 107.4 8.9 6.6e-08 32.7 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 GAN09402.1 - 5.1e-30 100.2 1.6 1.9e-07 30.8 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ribosomal_S8e PF01201.22 GAN09403.1 - 1.5e-51 174.1 0.6 2.8e-51 173.3 0.6 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Tnp_22_trimer PF17489.2 GAN09403.1 - 0.28 11.2 0.2 0.28 11.2 0.2 2.7 3 0 0 3 3 3 0 L1 transposable element trimerization domain BTB_2 PF02214.22 GAN09404.1 - 2.1e-19 69.6 0.0 7.8e-19 67.8 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide PF00805.22 GAN09404.1 - 0.12 12.0 0.1 9.6 6.0 0.1 3.0 4 0 0 4 4 4 0 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GAN09404.1 - 0.13 12.5 1.2 0.61 10.3 1.1 2.0 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) MSV199 PF10553.9 GAN09404.1 - 0.24 11.6 8.1 0.19 12.0 3.8 2.4 1 1 1 2 2 2 0 MSV199 domain tRNA-synt_1 PF00133.22 GAN09405.1 - 3.5e-176 587.0 1.5 5.4e-176 586.4 1.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAN09405.1 - 4e-23 82.1 1.3 8.6e-23 81.0 1.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAN09405.1 - 1.6e-18 66.7 0.4 3.2e-11 42.6 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAN09405.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAN09405.1 - 0.074 12.4 0.1 16 4.7 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Rop-like PF05082.13 GAN09405.1 - 0.12 12.3 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Rop-like LRR_8 PF13855.6 GAN09408.1 - 7.3e-18 64.1 29.3 6.7e-11 41.8 6.2 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAN09408.1 - 1.2e-12 47.8 21.9 3.1e-06 27.4 1.3 3.4 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN09408.1 - 5.7e-06 26.2 9.4 0.5 11.1 0.2 5.6 3 1 1 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 GAN09408.1 - 0.00095 19.0 15.6 2.4 8.4 1.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat Eisosome1 PF12757.7 GAN09408.1 - 0.0074 16.5 0.5 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 Eisosome protein 1 LRR_9 PF14580.6 GAN09408.1 - 0.013 15.0 2.4 0.029 13.9 2.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeat Fungal_trans PF04082.18 GAN09409.1 - 2.5e-13 49.7 2.1 2.5e-13 49.7 2.1 3.3 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN09409.1 - 1.9e-05 24.7 9.0 4e-05 23.6 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 GAN09409.1 - 0.0013 18.4 11.9 0.0025 17.5 11.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tmemb_cc2 PF10267.9 GAN09409.1 - 0.0068 15.6 3.5 0.013 14.7 3.5 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein SPX PF03105.19 GAN09409.1 - 0.11 12.3 9.9 0.24 11.3 9.9 1.5 1 0 0 1 1 1 0 SPX domain DUF2236 PF09995.9 GAN09409.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Opy2 PF09463.10 GAN09409.1 - 0.78 10.1 3.2 0.59 10.5 0.9 2.0 2 0 0 2 2 2 0 Opy2 protein CCDC106 PF15794.5 GAN09409.1 - 1.9 8.2 9.2 6.3 6.4 9.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Thaumatin PF00314.17 GAN09410.1 - 3.9e-51 173.7 12.5 4.8e-51 173.4 12.5 1.1 1 0 0 1 1 1 1 Thaumatin family Iron_permease PF04120.12 GAN09411.1 - 8.8e-42 141.9 14.8 4.4e-19 68.5 2.4 4.1 4 0 0 4 4 4 4 Low affinity iron permease DUF5495 PF17599.2 GAN09411.1 - 0.2 11.9 1.0 8.2 6.8 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5495) zf-C2H2 PF00096.26 GAN09412.1 - 1.3e-11 44.2 24.0 1.3e-05 25.4 0.4 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN09412.1 - 8.8e-05 23.0 20.8 0.0089 16.8 0.3 5.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN09412.1 - 0.00015 22.0 1.0 0.00015 22.0 1.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain Zap1_zf2 PF18217.1 GAN09412.1 - 0.0012 18.8 2.8 0.0012 18.8 2.8 2.4 2 0 0 2 2 2 1 Zap1 zinc finger 2 FOXP-CC PF16159.5 GAN09412.1 - 0.0079 16.8 0.1 0.0079 16.8 0.1 10.3 9 3 3 12 12 12 2 FOXP coiled-coil domain DUF1314 PF07013.11 GAN09412.1 - 0.24 11.3 3.6 0.082 12.8 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1314) zf_ZIC PF18366.1 GAN09412.1 - 1.7 8.8 4.3 6.1 7.0 0.0 3.5 3 0 0 3 3 3 0 Zic proteins zinc finger domain DUF1364 PF07102.12 GAN09413.1 - 0.086 12.7 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) DUF5483 PF17581.2 GAN09413.1 - 0.12 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5483) DUF4942 PF13708.6 GAN09414.1 - 0.0085 16.1 0.1 0.058 13.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4942) WD40 PF00400.32 GAN09415.1 - 8.2e-31 105.6 7.3 3e-05 24.7 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat Sof1 PF04158.14 GAN09415.1 - 2.9e-26 91.5 14.3 4.3e-26 91.0 14.3 1.2 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.11 GAN09415.1 - 2.2e-09 37.5 0.7 4.3e-06 26.7 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 GAN09415.1 - 5.4e-06 26.6 0.0 0.14 12.5 0.0 4.8 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAN09415.1 - 0.012 14.3 0.7 3.6 6.2 0.1 3.3 3 1 2 5 5 5 0 Nup133 N terminal like WD40_like PF17005.5 GAN09415.1 - 0.014 14.7 0.2 5.2 6.3 0.0 2.8 2 1 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 GAN09415.1 - 0.023 13.7 0.1 0.2 10.6 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CUE PF02845.16 GAN09416.1 - 4.7e-11 42.2 0.1 9e-11 41.3 0.1 1.4 1 0 0 1 1 1 1 CUE domain 60KD_IMP PF02096.20 GAN09416.1 - 1.2 9.0 3.0 2.1 8.2 3.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Atg14 PF10186.9 GAN09416.1 - 2.6 7.0 8.9 4.9 6.2 8.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GvpD PF07088.11 GAN09417.1 - 0.087 11.4 0.1 0.096 11.3 0.1 1.0 1 0 0 1 1 1 0 GvpD gas vesicle protein RA PF00788.23 GAN09418.1 - 7e-12 45.8 3.4 5.1e-06 27.0 0.0 4.1 4 1 0 4 4 4 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 GAN09418.1 - 4.1e-08 32.7 0.0 1.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN09418.1 - 0.00024 20.9 0.0 0.00064 19.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 GAN09418.1 - 0.0022 18.2 0.1 0.0054 17.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 GAN09418.1 - 0.089 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 SH3 domain BPL_N PF09825.9 GAN09419.1 - 1e-112 377.0 0.0 1.3e-112 376.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 GAN09419.1 - 9.3e-22 77.3 0.0 1.6e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 GAN09419.1 - 4.8e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain GATase_3 PF07685.14 GAN09419.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Heme_oxygenase PF01126.20 GAN09420.1 - 6.8e-57 192.6 2.0 9.2e-57 192.1 2.0 1.2 1 0 0 1 1 1 1 Heme oxygenase COBRA PF04833.15 GAN09420.1 - 0.038 13.9 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 COBRA-like protein HsdM_N PF12161.8 GAN09420.1 - 0.064 13.9 0.7 0.18 12.4 0.7 1.9 1 1 0 1 1 1 0 HsdM N-terminal domain ABC_tran PF00005.27 GAN09423.1 - 1.2e-33 116.6 2.4 1.1e-17 64.9 0.0 4.7 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 GAN09423.1 - 4.7e-13 49.6 0.1 0.0045 16.8 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN09423.1 - 4.2e-10 39.4 0.0 0.12 11.8 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAN09423.1 - 5.2e-08 33.0 0.0 0.001 19.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAN09423.1 - 1.1e-07 32.1 0.6 0.14 12.4 0.0 4.5 6 0 0 6 6 3 2 AAA domain AAA_28 PF13521.6 GAN09423.1 - 1.2e-07 32.2 0.0 0.025 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 GAN09423.1 - 3.9e-07 30.5 0.0 0.053 14.0 0.0 4.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAN09423.1 - 5.3e-07 29.7 0.0 0.0053 16.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAN09423.1 - 6.4e-07 29.0 0.0 0.026 14.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 GAN09423.1 - 9e-07 29.5 0.0 0.028 14.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 GAN09423.1 - 5.3e-06 26.9 0.0 0.04 14.3 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain MeaB PF03308.16 GAN09423.1 - 6.6e-06 25.3 0.1 0.055 12.4 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 GAN09423.1 - 2.1e-05 24.9 0.0 0.31 11.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 GAN09423.1 - 2.4e-05 24.3 0.0 0.091 12.7 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_15 PF13175.6 GAN09423.1 - 2.6e-05 24.1 0.0 0.18 11.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain DUF815 PF05673.13 GAN09423.1 - 9.9e-05 21.6 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Chromo PF00385.24 GAN09423.1 - 0.00017 21.5 1.4 0.00038 20.3 0.2 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 GAN09423.1 - 0.00023 21.8 11.1 0.028 14.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain Vac14_Fab1_bd PF12755.7 GAN09423.1 - 0.00034 21.2 0.0 0.96 10.1 0.0 3.0 1 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAN09423.1 - 0.00034 20.6 4.2 21 5.7 0.0 6.0 7 0 0 7 7 5 0 HEAT repeat AAA_33 PF13671.6 GAN09423.1 - 0.00035 20.8 0.0 1.7 8.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 GAN09423.1 - 0.0004 20.2 0.0 0.47 10.2 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 GAN09423.1 - 0.00052 19.8 0.0 0.68 9.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain HEAT_2 PF13646.6 GAN09423.1 - 0.0011 19.3 1.7 12 6.4 0.0 3.8 2 1 1 4 4 4 0 HEAT repeats Rad17 PF03215.15 GAN09423.1 - 0.0013 18.7 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 GAN09423.1 - 0.0014 18.7 0.0 0.92 9.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain CLP1_P PF16575.5 GAN09423.1 - 0.0021 17.9 0.0 0.2 11.4 0.0 2.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 GAN09423.1 - 0.0035 17.5 1.3 0.91 9.6 0.0 3.2 4 0 0 4 4 2 1 Helicase HerA, central domain AAA_27 PF13514.6 GAN09423.1 - 0.0046 16.6 0.0 3.1 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAN09423.1 - 0.0048 16.7 0.0 4 7.1 0.0 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 GAN09423.1 - 0.01 15.5 0.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 GAN09423.1 - 0.013 15.3 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAN09423.1 - 0.013 14.7 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 GAN09423.1 - 0.014 15.2 0.0 0.5 10.1 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 GAN09423.1 - 0.016 15.2 0.1 4 7.3 0.0 3.3 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 GAN09423.1 - 0.021 14.9 0.3 1.4 8.9 0.0 2.9 3 0 0 3 3 2 0 Dynamin family AAA_7 PF12775.7 GAN09423.1 - 0.025 14.1 0.0 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region 4HB PF17947.1 GAN09423.1 - 0.026 14.6 0.0 0.13 12.3 0.0 2.2 1 0 0 1 1 1 0 Four helical bundle domain PRK PF00485.18 GAN09423.1 - 0.034 13.9 0.1 3.4 7.4 0.0 2.9 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 GAN09423.1 - 0.039 13.5 0.1 7.2 6.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 GAN09423.1 - 0.04 13.2 0.1 11 5.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 GAN09423.1 - 0.045 13.7 0.1 4.7 7.1 0.1 2.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 GAN09423.1 - 0.052 13.5 0.2 20 5.2 0.0 3.5 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 GAN09423.1 - 0.067 13.2 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 GAN09423.1 - 0.087 12.4 0.0 6.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 GAN09423.1 - 0.12 12.6 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 GAN09423.1 - 0.15 11.8 1.1 4.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase AAA_13 PF13166.6 GAN09423.1 - 0.33 9.5 5.4 5.7 5.5 0.0 3.6 5 0 0 5 5 3 0 AAA domain SPT2 PF08243.11 GAN09424.1 - 2e-19 70.2 22.9 2e-19 70.2 22.9 4.1 3 1 0 3 3 3 1 SPT2 chromatin protein Ribosomal_S5 PF00333.20 GAN09426.1 - 4.2e-29 100.3 1.0 9.3e-29 99.2 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAN09426.1 - 1.2e-24 85.6 0.1 1.9e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Carn_acyltransf PF00755.20 GAN09427.1 - 9.2e-207 688.3 0.0 1e-206 688.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Phage_T4_Gp30_7 PF06919.11 GAN09427.1 - 0.056 13.6 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 Phage Gp30.7 protein Mito_carr PF00153.27 GAN09428.1 - 3.5e-67 222.4 3.1 2.6e-22 78.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hemerythrin PF01814.23 GAN09430.1 - 0.071 13.7 1.1 0.11 13.1 1.0 1.3 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain HLH PF00010.26 GAN09432.1 - 1.5e-18 66.5 1.2 2.4e-18 65.8 0.1 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4085 PF13315.6 GAN09432.1 - 0.016 14.9 1.7 0.027 14.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF1978 PF09321.10 GAN09432.1 - 0.026 13.8 3.7 0.03 13.7 1.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) LCIB_C_CA PF18599.1 GAN09432.1 - 3.2 7.0 5.8 1 8.6 2.0 1.9 1 1 2 3 3 3 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DPBB_1 PF03330.18 GAN09433.1 - 1.5e-12 47.6 0.1 2.9e-12 46.7 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN09433.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Barwin family zinc_ribbon_2 PF13240.6 GAN09433.1 - 0.07 12.9 2.7 11 5.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain GATA-N PF05349.12 GAN09434.1 - 0.032 14.5 0.0 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal DPBB_1 PF03330.18 GAN09435.1 - 2.4e-12 47.0 0.0 3.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN09435.1 - 0.00085 19.2 0.2 0.0015 18.4 0.1 1.4 1 1 0 1 1 1 1 Barwin family Kinesin PF00225.23 GAN09436.1 - 8.9e-92 307.5 1.8 1.8e-91 306.5 1.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAN09436.1 - 6e-17 62.0 0.6 2.8e-16 59.8 0.1 2.4 2 1 0 2 2 2 1 Microtubule binding DUF364 PF04016.12 GAN09436.1 - 0.09 12.4 0.1 11 5.6 0.0 2.8 2 0 0 2 2 2 0 Putative heavy-metal chelation PKcGMP_CC PF16808.5 GAN09436.1 - 9.6 6.2 9.1 15 5.6 0.3 3.5 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EXOSC1 PF10447.9 GAN09437.1 - 2.8e-16 60.1 2.9 1.9e-12 47.7 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 GAN09437.1 - 9e-12 44.6 0.8 2.3e-11 43.3 0.4 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 GAN09437.1 - 0.01 16.2 1.0 0.089 13.2 1.0 2.3 1 1 0 1 1 1 1 S1 RNA binding domain RicinB_lectin_2 PF14200.6 GAN09439.1 - 6.6e-14 52.4 0.1 3.1e-05 24.6 0.0 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN09439.1 - 3.6e-09 36.9 0.0 9.9e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF3759 PF12585.8 GAN09439.1 - 0.00062 19.7 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) BSD PF03909.17 GAN09440.1 - 7.8e-12 45.0 0.7 1.9e-11 43.8 0.7 1.6 1 0 0 1 1 1 1 BSD domain MscS_porin PF12795.7 GAN09440.1 - 0.009 15.6 0.6 0.019 14.6 0.6 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain FlxA PF14282.6 GAN09440.1 - 0.068 13.2 0.3 0.068 13.2 0.3 2.0 2 0 0 2 2 2 0 FlxA-like protein TolA_bind_tri PF16331.5 GAN09440.1 - 0.086 12.9 0.3 0.16 12.0 0.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Rad17 PF03215.15 GAN09441.1 - 3.3e-22 79.3 0.8 1.2e-19 71.0 0.1 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 GAN09441.1 - 1.7e-08 35.0 0.1 6.7e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAN09441.1 - 1.5e-07 31.9 0.0 4.5e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAN09441.1 - 1.3e-05 25.5 0.1 0.00012 22.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 GAN09441.1 - 1.5e-05 24.3 0.1 3.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAN09441.1 - 0.00055 19.9 0.5 0.0017 18.2 0.1 1.9 1 1 1 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAN09441.1 - 0.00065 20.0 0.4 0.015 15.6 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAN09441.1 - 0.0021 18.1 0.0 0.0065 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 GAN09441.1 - 0.0027 18.0 0.0 0.0082 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 GAN09441.1 - 0.0048 16.9 1.9 0.0078 16.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 GAN09441.1 - 0.0085 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAN09441.1 - 0.01 16.4 2.7 0.012 16.1 0.7 2.4 2 1 0 2 2 2 0 ABC transporter CbiA PF01656.23 GAN09441.1 - 0.017 15.2 0.2 0.061 13.4 0.2 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 GAN09441.1 - 0.018 14.6 0.0 0.059 12.9 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAN09441.1 - 0.019 14.2 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.18 GAN09441.1 - 0.022 14.0 0.1 0.056 12.7 0.0 1.7 2 0 0 2 2 2 0 Septin dNK PF01712.19 GAN09441.1 - 0.027 14.3 0.3 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 GAN09441.1 - 0.03 14.3 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 GAN09441.1 - 0.031 14.0 0.5 0.086 12.6 0.5 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 GAN09441.1 - 0.035 14.3 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 GAN09441.1 - 0.051 13.7 2.9 0.24 11.5 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain DNA_pol3_delta PF06144.13 GAN09441.1 - 0.059 13.2 0.3 0.29 10.9 0.3 2.1 1 1 0 1 1 1 0 DNA polymerase III, delta subunit RuvB_N PF05496.12 GAN09441.1 - 0.076 12.8 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 GAN09441.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 GAN09441.1 - 3.1 8.3 6.9 1.5e+02 2.8 6.8 3.2 1 1 0 1 1 1 0 AAA domain Glutaredoxin PF00462.24 GAN09442.1 - 1.9e-18 66.4 0.1 3.5e-18 65.6 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 GAN09442.1 - 0.034 14.5 0.0 0.098 13.1 0.0 1.8 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 GAN09442.1 - 0.038 14.4 0.2 0.1 13.1 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 GAN09442.1 - 0.048 13.4 0.4 0.11 12.2 0.4 1.7 1 1 0 1 1 1 0 DSBA-like thioredoxin domain ARPC4 PF05856.12 GAN09443.1 - 1.6e-81 271.9 4.7 1.7e-81 271.7 4.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 GAN09443.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Sm_like domain DUF3997 PF13162.6 GAN09444.1 - 0.068 13.5 2.6 1 9.7 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3997) AhpC-TSA PF00578.21 GAN09445.1 - 3e-08 33.6 0.0 4.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family ThiF PF00899.21 GAN09446.1 - 3e-68 229.8 0.1 5.5e-68 229.0 0.1 1.3 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 GAN09446.1 - 8.1e-10 39.1 17.1 4.3e-08 33.4 0.6 3.6 3 1 1 4 4 4 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 GAN09446.1 - 4.9e-08 33.4 0.2 1.9e-07 31.6 0.2 2.1 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 GAN09446.1 - 0.00059 20.2 0.3 0.0028 18.1 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAN09446.1 - 0.001 19.1 0.8 0.0031 17.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FeoA PF04023.14 GAN09446.1 - 0.039 14.2 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 FeoA domain Ldh_1_N PF00056.23 GAN09446.1 - 0.13 12.3 1.6 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAN09446.1 - 0.26 11.6 3.7 0.87 9.9 0.9 2.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LETM1 PF07766.13 GAN09447.1 - 2.6e-106 354.9 2.2 2.6e-106 354.9 2.2 3.3 2 1 2 4 4 4 1 LETM1-like protein DUF3232 PF11554.8 GAN09447.1 - 0.00075 19.9 2.0 0.00075 19.9 2.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3232) SAP PF02037.27 GAN09447.1 - 0.0065 16.2 0.4 0.098 12.4 0.0 3.2 4 0 0 4 4 4 1 SAP domain HycH PF07450.11 GAN09447.1 - 0.041 14.3 1.0 0.24 11.8 1.0 2.4 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Redoxin PF08534.10 GAN09448.1 - 2.4e-33 114.9 0.0 2.7e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAN09448.1 - 1.5e-10 41.0 0.0 1.6e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MPP6 PF10175.9 GAN09449.1 - 1.9e-24 86.7 17.5 2.3e-24 86.4 17.5 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Utp14 PF04615.13 GAN09449.1 - 1.3e-05 24.0 17.7 1.4e-05 23.9 17.7 1.0 1 0 0 1 1 1 1 Utp14 protein Sec8_exocyst PF04048.14 GAN09450.1 - 1.7e-41 141.5 0.8 1e-40 138.9 0.1 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 GAN09450.1 - 7.2e-07 29.2 0.0 5.3e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 GAN09450.1 - 0.00031 20.1 4.2 0.00031 20.1 4.2 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Vps51 PF08700.11 GAN09450.1 - 2.2 8.4 6.6 7.4 6.7 1.6 3.8 3 0 0 3 3 3 0 Vps51/Vps67 Ribonuclease_3 PF00636.26 GAN09451.1 - 1.4e-44 151.0 0.0 1.3e-22 80.4 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 GAN09451.1 - 1.5e-25 89.2 0.6 5.1e-24 84.3 0.1 3.4 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 GAN09451.1 - 4.5e-24 85.0 0.0 1.1e-13 51.5 0.0 3.4 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 GAN09451.1 - 1.7e-19 70.2 0.1 6.1e-19 68.4 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN09451.1 - 1e-13 51.4 0.0 4.5e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 GAN09451.1 - 3.5e-12 46.7 0.0 8.6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PAZ PF02170.22 GAN09451.1 - 7.9e-06 25.7 0.1 1.7e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 PAZ domain SWI2_SNF2 PF18766.1 GAN09451.1 - 0.00029 20.6 0.1 0.00062 19.5 0.1 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 GAN09451.1 - 0.024 14.9 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAN09451.1 - 0.042 13.3 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Peptidase_M41 PF01434.18 GAN09452.1 - 1.1e-66 224.4 0.0 1.7e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAN09452.1 - 1.9e-43 148.1 0.0 5e-43 146.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) COX5A PF02284.16 GAN09452.1 - 1.9e-39 133.8 0.3 8.3e-39 131.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va AAA_lid_3 PF17862.1 GAN09452.1 - 6.2e-13 48.3 1.7 1.2e-12 47.4 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 GAN09452.1 - 2.4e-09 37.5 0.0 7.7e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 GAN09452.1 - 0.0058 17.0 0.6 0.11 12.9 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 GAN09452.1 - 0.0062 15.8 0.1 0.0095 15.2 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GAN09452.1 - 0.0074 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAN09452.1 - 0.014 15.4 0.0 0.048 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAN09452.1 - 0.021 15.1 0.0 0.86 9.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAN09452.1 - 0.06 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAN09452.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 GAN09452.1 - 0.11 12.6 0.0 0.42 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RRM_1 PF00076.22 GAN09453.1 - 8.6e-57 188.9 0.1 1.8e-19 69.3 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAN09453.1 - 1.9e-08 33.9 0.0 0.0078 15.8 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN09453.1 - 2.1e-07 30.7 0.0 0.001 18.9 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 GAN09453.1 - 6.7e-06 26.1 0.1 0.2 11.8 0.0 3.7 2 1 2 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GAN09453.1 - 0.0026 17.7 0.1 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 GAN09453.1 - 0.035 13.8 0.0 6.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Ras PF00071.22 GAN09454.1 - 1.6e-55 187.2 0.1 1.8e-55 187.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN09454.1 - 6.2e-21 74.8 0.0 8.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN09454.1 - 1.2e-10 41.1 0.0 1.4e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAN09454.1 - 0.00034 20.6 0.0 0.37 10.7 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAN09454.1 - 0.0023 18.0 0.0 0.0038 17.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAN09454.1 - 0.005 16.1 0.1 0.0072 15.5 0.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 GAN09454.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAN09454.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 GAN09454.1 - 0.041 14.4 0.0 0.059 13.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 GAN09454.1 - 0.065 13.6 0.0 0.079 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 GAN09454.1 - 0.14 11.6 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Fungal_trans PF04082.18 GAN09455.1 - 6.8e-36 123.7 0.0 1.5e-35 122.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_C PF02752.22 GAN09456.1 - 2e-13 51.0 1.9 4.1e-08 33.8 0.7 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN09456.1 - 4.7e-11 42.9 0.9 1.6e-07 31.5 0.2 3.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 GAN09456.1 - 1.8e-06 27.4 0.2 0.0083 15.3 0.0 2.5 2 1 0 2 2 2 2 Rgp1 Polyketide_cyc PF03364.20 GAN09457.1 - 3.1e-18 66.2 0.1 3.8e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Proteasome PF00227.26 GAN09458.1 - 1.8e-59 200.4 0.5 2.3e-59 200.1 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAN09458.1 - 6.7e-14 51.3 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SDA1 PF05285.12 GAN09459.1 - 1.5 8.2 21.4 2 7.7 21.4 1.2 1 0 0 1 1 1 0 SDA1 HAUS4 PF14735.6 GAN09460.1 - 7.3e-06 25.9 3.9 7.3e-06 25.9 3.9 1.7 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Nucleo_LEF-12 PF06256.11 GAN09460.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein WIYLD PF10440.9 GAN09460.1 - 0.068 13.0 0.8 1.2 9.0 0.1 2.5 1 1 1 2 2 2 0 Ubiquitin-binding WIYLD domain GlcNAc-1_reg PF18440.1 GAN09460.1 - 0.083 13.1 2.9 0.07 13.4 1.2 1.7 2 1 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain Pox_A_type_inc PF04508.12 GAN09460.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat PX PF00787.24 GAN09461.1 - 2e-21 76.1 0.6 2.6e-21 75.7 0.6 1.1 1 0 0 1 1 1 1 PX domain Carb_kinase PF01256.17 GAN09462.1 - 1.1e-59 201.8 0.1 1.4e-59 201.6 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 GAN09462.1 - 6.4e-09 35.6 0.1 1.3e-08 34.6 0.1 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 GAN09462.1 - 0.0026 17.2 0.6 0.0036 16.7 0.6 1.3 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family tRNA_int_endo PF01974.17 GAN09463.1 - 1.8e-16 59.9 0.0 3.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF658 PF04936.12 GAN09463.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF658) GMP_synt_C PF00958.22 GAN09464.1 - 3e-40 136.2 0.1 6.2e-40 135.2 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 GAN09464.1 - 1.4e-32 113.0 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 GAN09464.1 - 1.2e-08 34.4 0.1 2.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 GAN09464.1 - 5.2e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 GAN09464.1 - 0.002 17.7 0.1 0.14 11.6 0.0 2.7 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAN09464.1 - 0.0034 16.2 0.1 0.0086 14.9 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 GAN09464.1 - 0.01 15.4 0.1 0.025 14.2 0.1 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 GAN09464.1 - 0.054 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 PP-loop family HOASN PF14515.6 GAN09464.1 - 0.064 13.6 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices PAPS_reduct PF01507.19 GAN09464.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Glyco_hydro_4 PF02056.16 GAN09464.1 - 0.12 12.0 0.3 0.27 10.8 0.1 1.6 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Pur_DNA_glyco PF02245.16 GAN09465.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) FYRN PF05964.14 GAN09469.1 - 3.4e-15 55.6 0.1 6.3e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 GAN09469.1 - 1.2e-14 54.3 0.0 2.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus DUF2884 PF11101.8 GAN09469.1 - 0.049 13.1 1.6 0.076 12.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) bZIP_2 PF07716.15 GAN09470.1 - 9.3e-07 28.8 4.7 9.3e-07 28.8 4.7 2.0 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN09470.1 - 2e-05 24.6 5.3 5e-05 23.3 5.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor Macoilin PF09726.9 GAN09470.1 - 0.038 12.6 13.6 0.046 12.3 13.6 1.1 1 0 0 1 1 1 0 Macoilin family bZIP_Maf PF03131.17 GAN09470.1 - 3.3 8.3 10.6 0.41 11.2 5.2 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor OapA_N PF08525.11 GAN09471.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Opacity-associated protein A N-terminal motif ubiquitin PF00240.23 GAN09472.1 - 3.1e-18 65.3 0.3 5.4e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAN09472.1 - 1.2e-05 25.0 0.1 2.7e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAN09472.1 - 1.7e-05 25.3 0.1 2.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAN09472.1 - 0.00027 21.0 0.1 0.00055 20.0 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 GAN09472.1 - 0.00032 21.0 1.8 0.00032 21.0 1.8 2.1 1 1 1 2 2 2 1 Blt1 N-terminal domain MSA-2c PF12238.8 GAN09472.1 - 0.0064 16.5 1.8 0.62 10.0 0.1 2.2 2 0 0 2 2 2 2 Merozoite surface antigen 2c EBP50_C PF09007.11 GAN09472.1 - 0.083 13.9 1.1 2.4 9.1 0.0 2.3 2 0 0 2 2 2 0 EBP50, C-terminal DUF2057 PF09829.9 GAN09472.1 - 0.12 12.5 3.9 0.17 12.0 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Glypican PF01153.19 GAN09474.1 - 0.0059 15.5 1.0 0.0067 15.3 1.0 1.0 1 0 0 1 1 1 1 Glypican Fungus-induced PF10917.8 GAN09474.1 - 0.048 14.0 1.0 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Fungus-induced protein MCM PF00493.23 GAN09475.1 - 2.1e-101 337.7 0.7 3.4e-101 337.0 0.7 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAN09475.1 - 1.1e-40 138.4 1.0 2e-40 137.5 1.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAN09475.1 - 6.9e-27 93.7 0.7 6.9e-27 93.7 0.7 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 GAN09475.1 - 2.6e-25 88.8 2.3 7e-25 87.4 2.3 1.8 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 GAN09475.1 - 7.2e-20 71.5 0.3 1.9e-19 70.2 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAN09475.1 - 3.8e-08 33.0 0.0 6.3e-07 29.0 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAN09475.1 - 5.4e-05 23.1 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAN09475.1 - 0.00086 19.3 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAN09475.1 - 0.0016 18.2 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Med3 PF11593.8 GAN09476.1 - 6 6.0 9.7 9 5.4 9.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PPR_2 PF13041.6 GAN09477.1 - 7.2e-17 61.3 0.5 2.1e-09 37.4 0.0 3.3 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.20 GAN09477.1 - 3e-09 36.5 2.2 0.00079 19.5 0.0 4.5 3 1 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 GAN09477.1 - 2.5e-08 33.8 0.0 0.00093 19.2 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAN09477.1 - 1.8e-07 30.7 0.0 3.6e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAN09477.1 - 0.0017 18.0 0.0 11 5.8 0.0 3.7 3 0 0 3 3 3 2 PPR repeat Trigger_C PF05698.14 GAN09477.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Abhydrolase_3 PF07859.13 GAN09478.1 - 1.1e-19 71.2 0.0 1.4e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold RasGAP PF00616.19 GAN09479.1 - 2e-57 194.3 1.7 3.1e-57 193.6 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAN09479.1 - 2.3e-37 128.2 1.7 2.3e-37 128.2 1.7 2.7 3 0 0 3 3 3 1 RasGAP C-terminus RasGEF_N_2 PF14663.6 GAN09479.1 - 0.0042 17.5 2.2 0.012 16.0 0.6 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF5089 PF17002.5 GAN09479.1 - 0.053 13.4 0.5 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) CENP-Q PF13094.6 GAN09479.1 - 0.095 12.9 1.4 8.1 6.6 0.2 2.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CTK3 PF12243.8 GAN09479.1 - 0.099 12.6 0.8 2.8 8.0 0.0 3.6 4 0 0 4 4 4 0 CTD kinase subunit gamma CTK3 PP1_bind PF15276.6 GAN09479.1 - 0.11 12.8 0.4 24 5.3 0.2 2.6 2 0 0 2 2 2 0 Protein phosphatase 1 binding PMSR PF01625.21 GAN09479.1 - 0.17 12.0 1.6 3.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Peptide methionine sulfoxide reductase DUF3800 PF12686.7 GAN09479.1 - 0.17 12.5 0.9 1.9 9.2 0.9 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Ribosomal_L7Ae PF01248.26 GAN09480.1 - 1.4e-05 24.7 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aminotran_4 PF01063.19 GAN09481.1 - 1.2e-18 67.8 0.0 1.6e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV THUMP PF02926.17 GAN09482.1 - 0.0042 17.2 0.1 0.0077 16.3 0.1 1.4 1 0 0 1 1 1 1 THUMP domain Glyco_transf_20 PF00982.21 GAN09483.1 - 2.2e-197 656.4 0.0 2.9e-197 656.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN09483.1 - 2.3e-54 184.0 0.0 4.7e-54 183.0 0.0 1.5 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 GAN09483.1 - 8.3e-06 25.7 0.0 2.5e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.6 GAN09483.1 - 0.00063 20.2 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-Tim10_DDP PF02953.15 GAN09484.1 - 1.2e-24 85.7 0.1 1.5e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PBD PF00786.28 GAN09486.1 - 6.8e-05 23.2 0.0 0.00031 21.1 0.0 2.1 1 1 0 1 1 1 1 P21-Rho-binding domain zf-C2H2_4 PF13894.6 GAN09487.1 - 1.2e-05 25.8 13.4 0.002 18.8 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN09487.1 - 6.5e-05 23.2 19.9 0.0082 16.6 2.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 GAN09487.1 - 0.0022 17.7 4.0 0.0022 17.7 4.0 3.5 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 GAN09487.1 - 0.018 15.3 2.6 0.018 15.3 2.6 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 GAN09487.1 - 0.1 12.5 2.4 0.12 12.2 1.4 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn_Tnp_IS1595 PF12760.7 GAN09487.1 - 0.16 11.9 3.1 0.33 11.0 3.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_jaz PF12171.8 GAN09487.1 - 0.3 11.4 7.8 0.35 11.2 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 GAN09487.1 - 0.49 10.9 13.2 0.22 12.0 2.3 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Elf1 PF05129.13 GAN09487.1 - 1.5 8.9 7.2 10 6.3 1.2 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-ISL3 PF14690.6 GAN09487.1 - 3.4 8.4 8.0 5.7 7.7 2.3 2.7 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zw10 PF06248.13 GAN09488.1 - 2.9e-37 128.5 4.9 1.6e-33 116.1 4.3 2.2 1 1 1 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 GAN09488.1 - 2.1e-09 37.4 0.3 4.9e-09 36.2 0.3 1.7 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal P_C10 PF14974.6 GAN09488.1 - 0.017 15.2 3.5 0.027 14.5 0.5 2.7 3 0 0 3 3 3 0 Protein C10 RNA_pol_Rpb4 PF03874.16 GAN09488.1 - 0.034 14.5 0.6 2 8.8 0.0 3.6 2 2 0 2 2 2 0 RNA polymerase Rpb4 DUF3848 PF12959.7 GAN09488.1 - 0.034 14.2 3.2 0.044 13.8 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Occludin_ELL PF07303.13 GAN09488.1 - 0.27 12.0 4.5 15 6.3 0.0 3.3 2 1 0 2 2 2 0 Occludin homology domain Sec8_exocyst PF04048.14 GAN09488.1 - 0.31 10.9 12.0 3 7.7 9.1 2.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain COPI_C PF06957.11 GAN09488.1 - 2.5 6.8 9.4 0.14 10.9 3.5 2.0 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus zinc_ribbon_16 PF17034.5 GAN09489.1 - 2.2e-25 89.3 12.0 6.3e-25 87.8 12.0 1.9 1 0 0 1 1 1 1 Zinc-ribbon like family DUF2722 PF10846.8 GAN09489.1 - 0.00098 18.2 6.9 0.00098 18.2 6.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 GAN09489.1 - 0.037 14.0 16.5 0.1 12.6 8.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 GAN09489.1 - 0.18 10.7 18.6 0.4 9.6 18.6 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Zn_ribbon_17 PF17120.5 GAN09489.1 - 2.7 7.7 16.3 0.41 10.3 11.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Senescence PF06911.12 GAN09490.1 - 4.3e-34 118.4 5.3 4.3e-34 118.4 5.3 1.8 2 0 0 2 2 2 1 Senescence-associated protein TPPII PF12580.8 GAN09490.1 - 0.089 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II tRNA_int_endo PF01974.17 GAN09491.1 - 5.3e-22 77.7 0.0 9.6e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 GAN09491.1 - 4.8e-06 26.2 0.0 5.7e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Polysacc_deac_1 PF01522.21 GAN09492.1 - 4e-25 88.1 0.0 7.5e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN09492.1 - 0.00055 19.2 0.1 0.039 13.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 57 DAO_C PF16901.5 GAN09493.1 - 2e-43 147.3 0.0 4.6e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 GAN09493.1 - 4.4e-32 112.0 0.0 6.4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAN09493.1 - 0.004 16.3 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Alginate_lyase2 PF08787.11 GAN09493.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Alginate lyase Kri1_C PF12936.7 GAN09495.1 - 2.6e-29 101.2 3.2 2.6e-29 101.2 3.2 4.4 2 2 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 GAN09495.1 - 1.2e-22 80.4 7.3 1.2e-22 80.4 7.3 5.6 4 1 1 6 6 6 1 KRI1-like family Pkinase PF00069.25 GAN09496.1 - 1.5e-52 178.6 0.0 2.1e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09496.1 - 7.4e-26 91.0 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN09496.1 - 0.0038 16.2 0.3 0.0068 15.4 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN09496.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAN09496.1 - 0.13 11.8 1.1 0.56 9.8 0.1 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase TB2_DP1_HVA22 PF03134.19 GAN09497.1 - 1.3e-31 108.3 5.9 1.3e-31 108.3 5.9 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Ribosom_S12_S23 PF00164.25 GAN09498.1 - 6.6e-51 170.7 0.8 1.1e-50 170.0 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF502 PF04367.13 GAN09498.1 - 0.18 11.7 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF502) Isochorismatase PF00857.20 GAN09499.1 - 1.6e-35 122.8 0.0 2e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NYN PF01936.18 GAN09499.1 - 0.0024 18.4 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain zf-UBP PF02148.19 GAN09500.1 - 2.4e-18 66.2 7.0 2.4e-18 66.2 7.0 2.5 3 0 0 3 3 2 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 GAN09500.1 - 3e-15 56.2 0.0 6.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 GAN09500.1 - 1.7e-08 34.6 9.3 1.7e-08 34.6 9.3 2.3 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 GAN09500.1 - 5.4e-06 26.6 6.3 5.4e-06 26.6 6.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAN09500.1 - 1.6e-05 24.9 4.7 4.4e-05 23.5 4.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAN09500.1 - 5.9e-05 23.0 5.1 5.9e-05 23.0 5.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAN09500.1 - 8.5e-05 22.3 8.7 8.5e-05 22.3 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN09500.1 - 0.00013 21.7 9.7 0.00013 21.7 9.7 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN09500.1 - 0.00043 20.0 7.0 0.00043 20.0 7.0 2.3 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 GAN09500.1 - 0.0014 18.5 7.0 0.0014 18.5 7.0 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN09500.1 - 0.012 15.5 6.3 0.012 15.5 6.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 GAN09500.1 - 0.044 13.9 16.1 0.085 13.0 16.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 GAN09500.1 - 0.31 11.5 12.7 1.2 9.6 12.5 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) zf-RING_4 PF14570.6 GAN09500.1 - 0.32 10.8 10.8 0.036 13.8 6.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YabA PF06156.13 GAN09500.1 - 0.38 11.4 10.8 0.1 13.2 5.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 GAN09500.1 - 0.78 9.9 22.7 0.19 11.8 18.9 1.9 1 1 1 2 2 2 0 Tropomyosin like Sec20 PF03908.13 GAN09500.1 - 1.1 9.3 8.7 4.9 7.1 0.1 2.7 2 1 0 2 2 2 0 Sec20 TMPIT PF07851.13 GAN09500.1 - 4.1 6.5 8.0 6.9 5.8 8.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein ECH_2 PF16113.5 GAN09502.1 - 1.5e-108 363.2 0.0 2e-108 362.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAN09502.1 - 2.2e-27 96.0 0.0 1.8e-25 89.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase KH_1 PF00013.29 GAN09503.1 - 5.8e-25 86.9 0.9 1.6e-08 34.2 0.0 6.8 7 0 0 7 7 7 5 KH domain CHDCT2 PF08074.11 GAN09503.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.6 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain Pkinase PF00069.25 GAN09504.1 - 1.9e-66 224.1 0.0 2.6e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09504.1 - 1.4e-35 122.9 0.0 2.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 GAN09504.1 - 4.1e-20 71.8 0.0 8.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 GAN09504.1 - 2.7e-06 26.9 0.0 5.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN09504.1 - 0.0058 15.6 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN09504.1 - 0.011 15.1 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN09504.1 - 0.031 14.2 0.3 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN09504.1 - 0.039 12.7 1.3 0.053 12.3 0.1 1.8 2 0 0 2 2 2 0 Fungal protein kinase CN_hydrolase PF00795.22 GAN09505.1 - 1.7e-40 139.1 0.0 2.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 GAN09505.1 - 4.2e-23 81.7 0.0 8.9e-23 80.6 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 GAN09505.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ADH_N PF08240.12 GAN09506.1 - 1.5e-31 108.5 3.6 1.9e-31 108.2 2.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN09506.1 - 2.5e-21 76.0 0.4 3.8e-21 75.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAN09506.1 - 2.8e-08 33.5 3.4 6.8e-07 29.0 3.4 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAN09506.1 - 0.00011 23.2 0.0 0.00023 22.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAN09506.1 - 0.00024 20.5 1.2 0.0011 18.4 1.2 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain MTS PF05175.14 GAN09506.1 - 0.0029 17.2 0.1 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAN09506.1 - 0.0031 18.2 0.0 0.0086 16.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 GAN09506.1 - 0.02 14.5 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1647 PF07801.11 GAN09506.1 - 0.041 13.6 0.1 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) PrmA PF06325.13 GAN09506.1 - 0.12 11.8 1.4 5.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RRM_1 PF00076.22 GAN09507.1 - 9.2e-20 70.2 0.1 1.3e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN09507.1 - 0.03 14.3 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAN09507.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif CCDC53 PF10152.9 GAN09507.1 - 3.9 7.9 6.9 21 5.5 2.1 2.9 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex PAS PF00989.25 GAN09508.1 - 1.4e-12 47.6 0.1 2.2e-07 30.8 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 GAN09508.1 - 8.8e-09 35.5 0.1 2.6e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 GAN09508.1 - 1.2e-06 28.6 0.0 5.3e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 PAS domain PAS_9 PF13426.7 GAN09508.1 - 1e-05 25.7 0.1 0.019 15.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 GAN09508.1 - 1.8e-05 25.0 0.0 0.016 15.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold SURF4 PF02077.15 GAN09509.1 - 1.8e-92 309.7 9.3 2.1e-92 309.5 9.3 1.0 1 0 0 1 1 1 1 SURF4 family Bunya_G2 PF03563.13 GAN09509.1 - 0.09 12.0 0.9 0.15 11.3 0.9 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 DoxX PF07681.12 GAN09509.1 - 3.1 8.4 18.9 0.18 12.4 4.0 3.3 2 1 1 3 3 3 0 DoxX Halogen_Hydrol PF10112.9 GAN09509.1 - 4.1 7.4 7.5 12 5.9 0.3 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Aldose_epim PF01263.20 GAN09510.1 - 4.5e-47 160.8 0.2 5e-47 160.7 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase HTH_Tnp_Tc3_2 PF01498.18 GAN09512.1 - 8.8e-10 38.7 0.0 1.1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Transposase N_formyltrans_C PF18216.1 GAN09512.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain SSB PF00436.25 GAN09513.1 - 2e-21 76.0 0.2 2.4e-21 75.7 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 GAN09513.1 - 0.075 13.0 0.1 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RecJ_OB PF17768.1 GAN09513.1 - 0.1 12.8 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RecJ OB domain Bac_export_3 PF01313.19 GAN09514.1 - 0.011 15.6 2.6 0.015 15.3 0.3 2.4 2 0 0 2 2 2 0 Bacterial export proteins, family 3 DUF3852 PF12963.7 GAN09514.1 - 0.13 12.7 0.4 0.13 12.7 0.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) Fungus-induced PF10917.8 GAN09514.1 - 0.6 10.5 2.5 16 5.9 0.1 2.6 2 0 0 2 2 2 0 Fungus-induced protein Kinesin PF00225.23 GAN09515.1 - 4e-96 321.8 0.4 4e-96 321.8 0.4 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN09515.1 - 6.3e-18 65.1 2.1 2e-16 60.3 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Fibin PF15819.5 GAN09515.1 - 0.085 12.6 5.0 0.2 11.4 5.0 1.5 1 0 0 1 1 1 0 Fin bud initiation factor homologue WD40 PF00400.32 GAN09516.1 - 8.6e-36 121.3 15.2 1.1e-06 29.3 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 GAN09516.1 - 6.6e-11 41.9 1.8 6.8e-11 41.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 GAN09516.1 - 1.3e-10 41.5 1.4 1.2 9.5 0.1 5.4 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAN09516.1 - 3.7e-10 39.4 0.4 1.5e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 GAN09516.1 - 1.2e-09 37.5 7.7 0.04 12.6 0.2 5.3 3 1 2 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 GAN09516.1 - 1.2e-05 24.9 0.4 0.011 15.1 0.1 3.0 1 1 1 3 3 3 1 WD40-like domain F-box_4 PF15966.5 GAN09516.1 - 2.3e-05 24.3 0.0 7.8e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 F-box PQQ_2 PF13360.6 GAN09516.1 - 0.00059 19.5 0.7 0.019 14.5 0.1 2.3 1 1 1 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 GAN09516.1 - 0.0024 16.9 4.8 0.39 9.6 0.4 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 GAN09516.1 - 0.0049 15.8 1.6 4.1 6.2 0.0 3.7 1 1 2 4 4 4 1 Partner and localizer of BRCA2 WD40 domain PRANC PF09372.10 GAN09516.1 - 0.026 14.8 0.0 0.36 11.2 0.1 2.5 2 0 0 2 2 2 0 PRANC domain MgtE_N PF03448.17 GAN09516.1 - 0.056 14.1 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain EI24 PF07264.11 GAN09519.1 - 1e-10 42.1 1.9 1.5e-10 41.7 1.9 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) IQ PF00612.27 GAN09519.1 - 0.27 11.1 1.5 0.44 10.5 0.2 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Bromodomain PF00439.25 GAN09520.1 - 8.9e-18 64.2 0.3 1.9e-17 63.1 0.3 1.6 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 GAN09520.1 - 8.4e-10 38.4 1.5 0.00033 20.1 0.5 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09520.1 - 0.00029 20.2 0.7 0.65 9.2 0.7 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 GAN09520.1 - 0.022 14.4 0.2 0.046 13.3 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Got1 PF04178.12 GAN09521.1 - 1.3e-18 67.4 4.4 1.5e-18 67.3 4.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Cyclin_N PF00134.23 GAN09523.1 - 4.3e-37 126.7 0.1 3e-35 120.7 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAN09523.1 - 2.6e-26 92.1 0.1 9.9e-26 90.2 0.1 2.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Gly_transf_sug PF04488.15 GAN09524.1 - 6.4e-09 36.3 0.1 2.8e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Laminin_G_3 PF13385.6 GAN09524.1 - 1.3e-08 35.1 1.7 2.7e-08 34.1 1.7 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TcdA_TcdB PF12919.7 GAN09524.1 - 9.9e-05 21.8 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 GAN09524.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Glyco_hydro_125 PF06824.11 GAN09525.1 - 2.9e-154 513.9 0.0 3.4e-154 513.7 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MFS_1 PF07690.16 GAN09526.1 - 5.4e-38 130.8 24.4 1.3e-37 129.5 23.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAN09526.1 - 2.6e-05 23.7 12.6 3.3e-05 23.3 3.3 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF3185 PF11381.8 GAN09526.1 - 8.8 6.4 9.5 1.9 8.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Motile_Sperm PF00635.26 GAN09527.1 - 3.6e-25 87.9 1.0 6.6e-25 87.1 1.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CCDC106 PF15794.5 GAN09527.1 - 0.016 15.0 0.5 0.038 13.7 0.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Edc3_linker PF16598.5 GAN09527.1 - 0.36 11.5 2.8 0.39 11.4 0.2 2.3 1 1 1 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 Porin_3 PF01459.22 GAN09528.1 - 1.7e-66 224.5 2.8 1.9e-66 224.3 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tubulin PF00091.25 GAN09529.1 - 1.2e-68 231.2 0.0 1.7e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAN09529.1 - 7.5e-49 165.1 0.0 1.2e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAN09529.1 - 0.00046 19.9 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Helicase_C PF00271.31 GAN09530.1 - 0.0015 18.9 0.0 0.0042 17.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HLH PF00010.26 GAN09532.1 - 4.2e-12 45.8 0.1 4.2e-12 45.8 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2229 PF09989.9 GAN09532.1 - 1.7 8.2 4.9 0.84 9.2 1.7 1.9 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) His_Phos_2 PF00328.22 GAN09533.1 - 6e-25 88.4 0.0 1.2e-13 51.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) BTB_2 PF02214.22 GAN09534.1 - 1.4e-15 57.4 0.3 2.8e-15 56.4 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAN09534.1 - 0.011 16.0 0.6 0.11 12.7 0.1 2.1 1 1 1 2 2 2 0 BTB/POZ domain Alpha_GJ PF03229.13 GAN09535.1 - 0.022 15.3 1.9 2.6 8.6 3.2 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J PepSY_TM PF03929.16 GAN09535.1 - 0.034 13.8 0.1 0.066 12.9 0.0 1.4 2 0 0 2 2 2 0 PepSY-associated TM region DSPc PF00782.20 GAN09536.1 - 4.6e-06 26.5 0.0 6.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN09536.1 - 0.00044 19.9 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Cwf_Cwc_15 PF04889.12 GAN09537.1 - 1.2 8.8 6.8 2.8 7.6 6.8 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_47 PF01532.20 GAN09538.1 - 1e-165 552.1 0.0 1.2e-165 551.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 GAN09538.1 - 0.0045 16.6 0.6 2.7 7.4 0.0 3.1 3 0 0 3 3 3 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 GAN09538.1 - 0.055 12.7 0.1 1.3 8.2 0.0 2.7 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Mito_carr PF00153.27 GAN09539.1 - 1.5e-61 204.4 1.9 5.7e-20 71.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PSI PF01437.25 GAN09539.1 - 0.00037 21.0 11.3 0.00084 19.8 11.3 1.6 1 0 0 1 1 1 1 Plexin repeat Shisa PF13908.6 GAN09539.1 - 0.0017 18.6 1.7 0.0031 17.8 1.7 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mucin PF01456.17 GAN09539.1 - 0.088 12.8 0.1 0.41 10.6 0.1 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Serine_protease PF18405.1 GAN09539.1 - 0.12 11.6 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Prominin PF05478.11 GAN09539.1 - 0.44 8.4 6.8 0.71 7.8 6.8 1.2 1 0 0 1 1 1 0 Prominin Polysacc_deac_1 PF01522.21 GAN09540.1 - 1.1e-17 64.0 0.0 1.9e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.25 GAN09541.1 - 2.2e-45 155.1 0.0 5.2e-37 127.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09541.1 - 2.9e-26 92.3 0.0 2.4e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAN09541.1 - 0.00064 19.7 0.1 0.00096 19.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAN09541.1 - 0.0034 16.4 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase ANTH PF07651.16 GAN09543.1 - 3.3e-50 170.6 2.3 3.3e-50 170.6 2.3 1.6 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 GAN09543.1 - 1.1e-08 35.2 0.1 2.3e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 ENTH domain Ribosomal_L5_C PF00673.21 GAN09545.1 - 2.5e-22 78.9 0.0 6.4e-22 77.5 0.0 1.7 1 1 1 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAN09545.1 - 1e-20 73.8 0.0 2.9e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Cellulase PF00150.18 GAN09546.1 - 3e-12 46.5 0.2 1.3e-11 44.5 0.2 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MBOAT PF03062.19 GAN09547.1 - 9e-38 130.5 20.2 9e-38 130.5 20.2 2.1 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAN09547.1 - 0.00032 20.9 1.9 0.0011 19.2 1.9 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family F-box-like PF12937.7 GAN09548.1 - 0.00011 22.0 0.1 0.00061 19.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like DUSP PF06337.12 GAN09548.1 - 0.00027 21.5 0.0 0.00074 20.1 0.0 1.7 1 0 0 1 1 1 1 DUSP domain F-box PF00646.33 GAN09548.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain C1_1 PF00130.22 GAN09548.1 - 0.11 12.4 6.5 0.54 10.2 4.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ferritin-like PF12902.7 GAN09550.1 - 0.12 12.2 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 Ferritin-like Cwf_Cwc_15 PF04889.12 GAN09550.1 - 0.28 10.9 9.6 0.35 10.6 9.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GOLD_2 PF13897.6 GAN09550.1 - 1.3 9.5 3.4 1.4 9.4 2.6 1.4 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking NOA36 PF06524.12 GAN09550.1 - 4.9 6.4 11.4 6.4 6.0 11.4 1.1 1 0 0 1 1 1 0 NOA36 protein Integrase_H2C2 PF17921.1 GAN09551.1 - 5.3e-06 26.5 0.5 1.1e-05 25.4 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Ntox4 PF15541.6 GAN09551.1 - 0.16 12.4 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial toxin 4 Brix PF04427.18 GAN09553.1 - 3.4e-45 154.5 0.1 5.2e-45 153.9 0.1 1.3 1 0 0 1 1 1 1 Brix domain Cupredoxin_1 PF13473.6 GAN09553.1 - 0.1 12.7 0.3 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 Cupredoxin-like domain Metallophos PF00149.28 GAN09554.1 - 1.6e-11 45.1 0.8 2.7e-11 44.4 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.18 GAN09555.1 - 6.9e-20 71.2 3.7 1.5e-19 70.0 3.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 GAN09555.1 - 0.073 13.1 14.0 0.049 13.7 10.4 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAN09555.1 - 0.54 9.8 15.9 1 9.0 15.9 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 GAN09555.1 - 1.5 9.8 5.0 4.6 8.3 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Menin PF05053.13 GAN09555.1 - 5.3 5.3 5.8 8.7 4.6 5.8 1.2 1 0 0 1 1 1 0 Menin WRKY PF03106.15 GAN09556.1 - 7e-11 42.2 1.4 1.3e-10 41.3 1.4 1.4 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.16 GAN09556.1 - 0.035 14.2 0.4 0.069 13.3 0.4 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain DLIC PF05783.11 GAN09556.1 - 0.056 12.3 2.6 0.093 11.5 2.6 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF3275 PF11679.8 GAN09556.1 - 0.59 10.1 4.6 0.48 10.4 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) GET2 PF08690.10 GAN09556.1 - 2.7 7.6 15.5 1.1 8.9 7.7 2.2 1 1 1 2 2 2 0 GET complex subunit GET2 GST_N_3 PF13417.6 GAN09557.1 - 1.2e-13 51.3 0.1 3e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAN09557.1 - 3.7e-05 23.7 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAN09557.1 - 6.6e-05 23.1 0.0 0.00022 21.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAN09557.1 - 0.11 13.2 0.0 0.4 11.5 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Ribosomal_L13e PF01294.18 GAN09558.1 - 1.4e-78 262.9 4.7 1.9e-78 262.4 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e G_glu_transpept PF01019.21 GAN09559.1 - 3.3e-136 455.1 0.0 3.7e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase BET PF17035.5 GAN09560.1 - 9.8e-05 22.5 0.6 9.8e-05 22.5 0.6 2.6 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Tcp11 PF05794.13 GAN09561.1 - 6.5e-86 289.1 15.7 6.5e-86 289.1 15.7 3.2 2 1 0 3 3 3 2 T-complex protein 11 PfkB PF00294.24 GAN09562.1 - 1.2e-27 97.0 0.1 1.7e-27 96.5 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Chal_sti_synt_C PF02797.15 GAN09562.1 - 0.074 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain GATA PF00320.27 GAN09563.1 - 7.9e-15 54.2 5.4 7.9e-15 54.2 5.4 2.2 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN09563.1 - 0.0034 16.9 2.1 0.0068 15.9 2.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding eIF-5_eIF-2B PF01873.17 GAN09563.1 - 2.4 8.0 5.7 0.99 9.3 0.7 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 FAD_binding_3 PF01494.19 GAN09566.1 - 6.6e-61 206.5 0.0 1.7e-60 205.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAN09566.1 - 0.017 15.7 0.0 1.8 9.2 0.0 2.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FBA_1 PF07734.13 GAN09566.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 F-box associated DAO PF01266.24 GAN09566.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAN09566.1 - 0.12 11.4 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAN09566.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Oxysterol_BP PF01237.18 GAN09567.1 - 7e-70 235.7 7.7 6.2e-60 203.0 0.7 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein SRP54 PF00448.22 GAN09568.1 - 1.8e-77 259.4 1.6 3.7e-77 258.4 1.6 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAN09568.1 - 2.9e-34 117.7 3.4 2.9e-34 117.7 3.4 5.0 3 1 2 5 5 4 2 Signal peptide binding domain SRP54_N PF02881.19 GAN09568.1 - 2.8e-18 65.9 2.1 2.8e-18 65.9 2.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.19 GAN09568.1 - 1.7e-07 31.0 0.2 5.7e-07 29.3 0.2 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 GAN09568.1 - 0.00027 21.0 0.0 0.0008 19.5 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 GAN09568.1 - 0.00038 20.2 0.3 0.001 18.8 0.3 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN09568.1 - 0.00096 19.3 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 GAN09568.1 - 0.0012 17.9 2.1 0.0066 15.5 0.9 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 GAN09568.1 - 0.0017 17.9 0.1 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 GAN09568.1 - 0.0034 17.8 1.1 0.012 16.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAN09568.1 - 0.0036 16.6 0.0 0.0097 15.2 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_31 PF13614.6 GAN09568.1 - 0.0065 16.4 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 GAN09568.1 - 0.012 15.4 2.2 0.11 12.3 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.14 GAN09568.1 - 0.015 15.1 0.2 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 GAN09568.1 - 0.02 14.6 0.0 0.18 11.5 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.6 GAN09568.1 - 0.02 15.1 0.2 0.14 12.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAN09568.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 GAN09568.1 - 0.026 14.6 1.7 0.074 13.1 1.0 2.2 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit DUF4618 PF15397.6 GAN09568.1 - 0.03 13.7 1.8 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) NTPase_1 PF03266.15 GAN09568.1 - 0.045 13.7 1.0 0.16 11.8 0.1 2.2 1 1 1 2 2 2 0 NTPase MMR_HSR1 PF01926.23 GAN09568.1 - 0.045 13.8 0.8 0.25 11.4 0.2 2.5 2 1 0 2 2 1 0 50S ribosome-binding GTPase MipZ PF09140.11 GAN09568.1 - 0.053 12.8 0.1 1.4 8.1 0.1 2.4 1 1 0 1 1 1 0 ATPase MipZ DUF3418 PF11898.8 GAN09568.1 - 0.055 12.1 0.0 0.12 11.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3418) APS_kinase PF01583.20 GAN09568.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase VirC1 PF07015.11 GAN09568.1 - 0.066 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein AAA_19 PF13245.6 GAN09568.1 - 0.08 13.3 1.3 0.13 12.6 0.2 2.0 2 1 0 2 2 2 0 AAA domain DNA_ligase_A_N PF04675.14 GAN09568.1 - 0.12 12.7 0.2 0.53 10.6 0.1 2.2 2 1 1 3 3 2 0 DNA ligase N terminus CLP1_P PF16575.5 GAN09568.1 - 0.16 11.8 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA PF00004.29 GAN09568.1 - 1.3 9.5 5.0 1.7 9.1 0.9 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) YlbD_coat PF14071.6 GAN09568.1 - 6.9 6.9 6.9 6.1 7.1 0.9 3.2 1 1 1 2 2 2 0 Putative coat protein HSF_DNA-bind PF00447.17 GAN09569.1 - 1.2e-20 74.0 0.3 1.2e-20 74.0 0.3 2.8 3 0 0 3 3 3 1 HSF-type DNA-binding STE PF02200.16 GAN09570.1 - 0.029 14.8 0.1 0.13 12.7 0.1 2.2 2 0 0 2 2 2 0 STE like transcription factor Gasdermin PF04598.12 GAN09570.1 - 0.037 13.4 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Gasdermin pore forming domain Lactamase_B_2 PF12706.7 GAN09572.1 - 4.4e-09 36.1 0.0 0.00053 19.5 0.0 3.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAN09572.1 - 1e-07 32.2 0.1 2.5e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 GAN09572.1 - 2.7e-06 26.9 0.0 6.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease DUF2070 PF09843.9 GAN09573.1 - 1.8 6.8 21.8 0.061 11.6 11.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Thiolase_N PF00108.23 GAN09574.1 - 2e-94 315.8 2.7 2.9e-94 315.2 2.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN09574.1 - 4.2e-45 152.4 0.9 4.2e-45 152.4 0.9 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAN09574.1 - 8.7e-06 25.5 3.9 1.3e-05 24.9 1.4 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAN09574.1 - 0.23 11.3 3.0 5.5 6.9 0.3 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.32 GAN09575.1 - 6.7e-41 137.5 26.6 3.3e-06 27.7 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09575.1 - 1.8e-18 66.6 2.7 0.016 15.5 0.0 5.7 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAN09575.1 - 5.4e-12 45.4 1.1 1e-11 44.5 1.1 1.5 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 GAN09575.1 - 8.3e-09 35.2 0.1 0.00011 21.7 0.1 3.2 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 GAN09575.1 - 9.6e-08 31.1 13.5 0.07 11.8 0.0 6.3 4 2 3 7 7 7 3 Nucleoporin Nup120/160 F-box PF00646.33 GAN09575.1 - 1.2e-05 25.0 0.7 2.1e-05 24.3 0.7 1.4 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 GAN09575.1 - 0.0018 18.3 0.5 0.13 12.3 0.0 3.8 2 1 4 6 6 6 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 GAN09575.1 - 0.0026 16.7 1.8 3.5 6.5 0.3 4.2 1 1 2 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Vif PF00559.17 GAN09575.1 - 0.0057 16.4 0.2 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Retroviral Vif (Viral infectivity) protein DUF5046 PF16465.5 GAN09575.1 - 0.016 14.6 0.0 6.8 6.0 0.0 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF5046) eIF2A PF08662.11 GAN09575.1 - 0.062 13.2 0.0 0.67 9.8 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 GAN09575.1 - 0.1 12.3 0.1 67 3.1 0.0 3.6 2 1 1 3 3 3 0 TUP1-like enhancer of split PQQ_3 PF13570.6 GAN09575.1 - 0.1 13.1 1.8 3 8.5 0.0 4.1 4 1 1 5 5 5 0 PQQ-like domain Gtr1_RagA PF04670.12 GAN09578.1 - 3.8e-68 229.3 1.5 4.7e-68 229.0 1.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAN09578.1 - 1.3e-06 28.0 0.1 2e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN09578.1 - 0.00017 21.6 0.0 0.00044 20.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAN09578.1 - 0.00063 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAN09578.1 - 0.00086 19.5 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN09578.1 - 0.048 13.3 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Ras family DUF1473 PF07341.11 GAN09579.1 - 0.18 11.6 3.3 3 7.6 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1473) DUF4131 PF13567.6 GAN09579.1 - 0.25 11.0 1.0 0.36 10.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Rieske PF00355.26 GAN09580.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PIEZO PF15917.5 GAN09580.1 - 0.12 11.8 3.1 0.16 11.4 3.1 1.1 1 0 0 1 1 1 0 Piezo Methyltransf_4 PF02390.17 GAN09581.1 - 5.9e-60 201.7 0.0 7.2e-60 201.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 GAN09581.1 - 0.00043 20.9 0.0 0.00084 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN09581.1 - 0.0028 17.2 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAN09581.1 - 0.034 13.9 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAN09581.1 - 0.071 13.9 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAN09581.1 - 0.14 12.8 0.0 0.34 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Zip PF02535.22 GAN09583.1 - 1.3e-62 211.9 17.6 7.4e-62 209.5 17.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Arf PF00025.21 GAN09584.1 - 1.7e-67 226.3 2.4 3.3e-67 225.3 2.4 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_S24e PF01282.19 GAN09584.1 - 4.7e-36 122.6 0.1 9.7e-36 121.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e Roc PF08477.13 GAN09584.1 - 2.5e-15 56.8 0.6 4.5e-15 55.9 0.6 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN09584.1 - 1.5e-14 53.9 0.2 2.3e-14 53.3 0.2 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAN09584.1 - 9.1e-12 44.8 0.5 1.6e-11 44.0 0.5 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAN09584.1 - 4.4e-10 39.3 2.3 1.1e-07 31.4 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 GAN09584.1 - 1.3e-08 34.9 0.8 5e-08 33.0 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN09584.1 - 6.2e-07 29.0 0.5 1.1e-06 28.2 0.5 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 GAN09584.1 - 0.011 15.8 0.2 0.024 14.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 GAN09584.1 - 0.048 13.2 3.2 0.053 13.0 1.6 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 GAN09584.1 - 0.12 12.8 2.0 0.42 11.1 0.8 2.3 2 1 0 2 2 2 0 ABC transporter cobW PF02492.19 GAN09584.1 - 0.13 11.8 5.9 0.44 10.1 0.1 2.8 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain CotH PF08757.11 GAN09585.1 - 2.5e-43 148.8 7.7 4.1e-43 148.1 7.7 1.3 1 0 0 1 1 1 1 CotH kinase protein MASE3 PF17159.4 GAN09586.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated sensor domain Phi_1 PF04674.12 GAN09587.1 - 9.5e-21 74.3 0.4 1.4e-20 73.7 0.4 1.2 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region F-box PF00646.33 GAN09589.1 - 0.0026 17.6 0.3 0.0095 15.8 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN09589.1 - 0.0035 17.2 0.1 0.0074 16.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Terpene_synth_C PF03936.16 GAN09589.1 - 0.075 12.4 0.1 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain GTP_EFTU PF00009.27 GAN09590.1 - 1.2e-60 204.4 0.1 1.9e-60 203.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAN09590.1 - 1.1e-39 135.0 0.0 2.8e-39 133.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GAN09590.1 - 5.8e-30 103.2 0.0 1.5e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAN09590.1 - 2.6e-26 91.5 0.1 6e-26 90.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAN09590.1 - 2e-11 44.1 0.3 6.6e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAN09590.1 - 4e-06 26.7 0.0 8.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAN09590.1 - 0.0052 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AbfS_sensor PF18225.1 GAN09590.1 - 0.038 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain AIG1 PF04548.16 GAN09590.1 - 0.047 13.0 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family TP_methylase PF00590.20 GAN09591.1 - 1.8e-38 132.6 0.0 2.6e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 GAN09591.1 - 1.1e-28 99.7 0.0 3.4e-28 98.1 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 GAN09591.1 - 5e-16 58.1 2.3 5e-16 58.1 2.3 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 GAN09591.1 - 6.4e-12 44.7 0.1 1.3e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central AlaDh_PNT_C PF01262.21 GAN09591.1 - 0.027 13.8 0.5 0.076 12.3 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 GAN09591.1 - 0.06 12.7 0.5 0.096 12.0 0.0 1.8 2 1 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.19 GAN09591.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HA2 PF04408.23 GAN09592.1 - 3.7e-18 65.8 0.0 1.3e-17 64.1 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAN09592.1 - 1.8e-15 57.1 0.0 3.8e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAN09592.1 - 4.5e-15 56.0 0.1 1.1e-14 54.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 GAN09592.1 - 2.7e-14 53.4 0.2 6.8e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 GAN09592.1 - 5.5e-08 32.8 0.5 1.4e-07 31.4 0.5 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 GAN09592.1 - 0.0062 16.8 0.2 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 UBA PF00627.31 GAN09592.1 - 0.0075 16.2 0.0 2.4 8.2 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain AAA_22 PF13401.6 GAN09592.1 - 0.031 14.5 2.0 0.088 13.1 1.2 2.3 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 GAN09592.1 - 0.086 12.2 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 KaiC Ecl1 PF12855.7 GAN09593.1 - 1.9e-10 42.2 2.1 2e-10 42.1 2.1 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 GAN09593.1 - 0.078 13.1 0.9 0.078 13.1 0.9 1.6 2 0 0 2 2 2 0 MYND finger Homeodomain PF00046.29 GAN09594.1 - 4.9e-16 58.3 3.3 8.9e-16 57.5 3.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN09594.1 - 0.0022 17.9 0.4 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain Na_trans_assoc PF06512.13 GAN09594.1 - 0.0084 16.4 0.7 0.0095 16.2 0.7 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated HTH_23 PF13384.6 GAN09594.1 - 0.011 15.5 0.2 0.058 13.2 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain CDC45 PF02724.14 GAN09594.1 - 0.011 14.1 3.0 0.011 14.1 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GerE PF00196.19 GAN09594.1 - 0.096 12.2 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family PBP1_TM PF14812.6 GAN09594.1 - 2 8.8 13.2 0.067 13.6 6.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GAN09594.1 - 8 5.7 9.5 0.44 9.8 4.5 1.5 2 0 0 2 2 2 0 NOA36 protein FAM176 PF14851.6 GAN09594.1 - 8.6 6.0 7.1 13 5.5 6.8 1.5 1 1 0 1 1 1 0 FAM176 family zf-C2H2_2 PF12756.7 GAN09595.1 - 0.00034 20.9 4.4 0.0021 18.3 0.2 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAN09595.1 - 0.0059 17.0 7.4 0.0059 17.0 7.4 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-AD PF07776.15 GAN09595.1 - 0.0063 16.7 0.4 0.11 12.8 0.4 2.6 1 1 0 1 1 1 1 Zinc-finger associated domain (zf-AD) Defensin_5 PF18251.1 GAN09595.1 - 0.057 13.5 6.2 1.6 8.9 0.4 2.6 2 0 0 2 2 2 0 Fungal defensin Copsin zf-C2HCIx2C PF10782.9 GAN09595.1 - 0.5 10.3 4.9 1.2 9.1 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger Efg1 PF10153.9 GAN09596.1 - 2.2e-29 102.1 11.6 2.2e-29 102.1 11.6 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 RWD PF05773.22 GAN09596.1 - 0.0086 16.3 6.8 0.011 16.0 6.1 1.6 1 1 0 1 1 1 1 RWD domain TENA_THI-4 PF03070.16 GAN09596.1 - 0.39 10.5 6.0 0.71 9.6 1.6 2.1 1 1 1 2 2 2 0 TENA/THI-4/PQQC family Cwf_Cwc_15 PF04889.12 GAN09596.1 - 1.2 8.9 21.8 2.3 7.9 21.6 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Uds1 PF15456.6 GAN09596.1 - 1.5 9.0 15.5 0.27 11.4 10.1 2.4 1 1 0 2 2 2 0 Up-regulated During Septation E1-E2_ATPase PF00122.20 GAN09597.1 - 1.6e-43 148.4 0.8 1.6e-43 148.4 0.8 4.2 4 1 0 4 4 4 2 E1-E2 ATPase SPRY PF00622.28 GAN09597.1 - 1.7e-20 73.3 0.1 4.4e-20 72.0 0.1 1.8 2 0 0 2 2 2 1 SPRY domain Cation_ATPase_C PF00689.21 GAN09597.1 - 5.1e-18 65.4 3.8 5.1e-18 65.4 3.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 GAN09597.1 - 7.8e-18 63.9 0.0 2e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAN09597.1 - 1.2e-16 60.5 0.0 2.9e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN09597.1 - 7.6e-15 55.8 0.0 2.3e-13 50.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Borrelia_P13 PF05628.12 GAN09597.1 - 0.00041 20.3 1.9 0.0079 16.2 0.0 2.9 2 1 1 3 3 3 1 Borrelia membrane protein P13 Hydrolase_3 PF08282.12 GAN09597.1 - 0.0016 18.3 2.2 0.011 15.5 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AC_N PF16214.5 GAN09597.1 - 0.21 10.7 0.9 15 4.6 0.1 2.7 3 0 0 3 3 3 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Glutaredoxin PF00462.24 GAN09598.1 - 1.5e-18 66.7 0.0 2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 GAN09598.1 - 0.002 18.5 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 GAN09598.1 - 0.048 14.1 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 GAN09598.1 - 0.18 11.6 0.1 0.24 11.2 0.1 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain GST_N_2 PF13409.6 GAN09598.1 - 0.19 12.1 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PH PF00169.29 GAN09599.1 - 0.0036 17.8 1.0 0.016 15.7 0.5 2.2 2 0 0 2 2 2 1 PH domain RNase_P_Rpp14 PF01900.19 GAN09600.1 - 2.9e-08 33.9 0.1 3.6e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family PAS_3 PF08447.12 GAN09601.1 - 8.7e-13 48.4 0.0 5.7e-10 39.4 0.0 2.6 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 GAN09601.1 - 1.6e-07 31.3 0.0 0.00014 21.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 GAN09601.1 - 0.0021 18.3 0.0 0.87 9.9 0.0 2.4 2 1 0 2 2 2 2 PAS domain PAS_11 PF14598.6 GAN09601.1 - 0.0064 16.6 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_12 PF18095.1 GAN09601.1 - 0.022 14.4 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain STT3 PF02516.14 GAN09602.1 - 1.2e-153 512.6 40.9 3e-149 498.1 37.1 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pox_A14 PF05767.12 GAN09602.1 - 1 9.6 5.7 0.39 10.9 0.2 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 LidA_Long_CC PF18641.1 GAN09603.1 - 0.00016 21.8 0.6 0.00016 21.8 0.6 2.2 2 1 0 2 2 2 1 LidA long coiled-coil domain Tape_meas_lam_C PF09718.10 GAN09603.1 - 0.33 11.1 2.6 6.3 7.0 0.2 2.4 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phasin PF05597.11 GAN09603.1 - 0.53 10.3 4.3 0.25 11.4 0.2 2.4 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 GAN09603.1 - 0.6 10.2 5.3 3.3 7.7 0.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 GAN09603.1 - 4 7.9 10.2 4.5 7.7 6.0 3.0 2 1 0 2 2 2 0 Syntaxin-like protein DivIVA PF05103.13 GAN09603.1 - 4.2 7.5 7.6 3.9 7.6 1.4 3.1 2 1 0 3 3 3 0 DivIVA protein DASH_Dam1 PF08653.10 GAN09603.1 - 5.4 6.9 8.4 1.7 8.5 0.3 3.5 4 0 0 4 4 4 0 DASH complex subunit Dam1 Trehalase PF01204.18 GAN09604.1 - 6.7e-125 417.8 19.9 2e-115 386.5 10.8 2.1 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 GAN09604.1 - 9.6e-07 28.1 4.6 1.7e-05 24.0 4.6 2.1 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bul1_C PF04426.12 GAN09604.1 - 0.067 12.6 1.6 0.13 11.7 1.6 1.3 1 0 0 1 1 1 0 Bul1 C terminus F-box-like PF12937.7 GAN09605.1 - 0.12 12.3 0.4 0.9 9.5 0.0 2.8 3 0 0 3 3 3 0 F-box-like Exo_endo_phos PF03372.23 GAN09606.1 - 7.3e-22 78.0 0.1 1.1e-21 77.5 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_46 PF15977.5 GAN09606.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Pkinase PF00069.25 GAN09607.1 - 4.3e-39 134.5 0.0 5.2e-38 130.9 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09607.1 - 1.4e-14 54.1 0.0 1.2e-10 41.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN09607.1 - 0.002 16.9 0.0 0.002 16.9 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase TFIIA PF03153.13 GAN09607.1 - 0.19 11.7 26.2 0.28 11.1 26.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.11 GAN09607.1 - 1.3 9.0 13.8 2.7 8.0 13.8 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Polysacc_deac_1 PF01522.21 GAN09608.1 - 2.7e-20 72.5 0.1 4.9e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase PHD PF00628.29 GAN09609.1 - 3.9e-06 26.7 10.6 1.1e-05 25.2 10.6 1.9 1 0 0 1 1 1 1 PHD-finger GATA PF00320.27 GAN09609.1 - 0.00013 21.5 5.6 0.00038 20.0 5.6 1.8 1 0 0 1 1 1 1 GATA zinc finger zf-PHD-like PF15446.6 GAN09609.1 - 0.004 16.8 2.4 0.004 16.8 2.4 2.0 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-CHCC PF10276.9 GAN09609.1 - 0.0051 16.8 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger domain C1_1 PF00130.22 GAN09609.1 - 0.23 11.4 10.2 0.049 13.5 4.1 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 GAN09609.1 - 1 9.7 10.3 0.19 12.0 4.7 2.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain OST3_OST6 PF04756.13 GAN09610.1 - 1.1e-102 343.4 0.1 1.2e-102 343.2 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 GAN09610.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin MerC PF03203.14 GAN09610.1 - 2.1 8.8 6.0 4.3 7.8 0.1 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein DUF4131 PF13567.6 GAN09610.1 - 3.3 7.3 6.9 4.1 7.0 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2039 PF10217.9 GAN09611.1 - 9.6e-28 96.4 17.4 1.5e-27 95.7 17.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) DUF702 PF05142.12 GAN09611.1 - 0.063 13.8 7.5 0.031 14.8 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Cript PF10235.9 GAN09611.1 - 2.9 8.5 22.7 28 5.4 22.7 2.3 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Rsa3 PF14615.6 GAN09612.1 - 1.3e-18 66.3 0.0 2.7e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Ribosome-assembly protein 3 UNC-79 PF14776.6 GAN09612.1 - 0.51 9.0 4.6 0.67 8.6 4.6 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 SDA1 PF05285.12 GAN09612.1 - 2.5 7.5 24.3 3 7.2 24.3 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAN09612.1 - 4.7 5.3 28.1 5.5 5.1 28.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAN09612.1 - 6.8 4.7 26.7 7.8 4.5 26.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2627 PF11118.8 GAN09613.1 - 0.0036 17.8 0.0 0.0065 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2627) PTP_tm PF18861.1 GAN09613.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Ribosomal_S8e PF01201.22 GAN09614.1 - 6.1e-53 178.7 0.8 2.1e-52 176.9 0.8 1.9 1 0 0 1 1 1 1 Ribosomal protein S8e SPX PF03105.19 GAN09614.1 - 1.5e-34 120.6 14.8 1.6e-27 97.4 2.8 3.3 3 0 0 3 3 3 2 SPX domain Ribosomal_L5_C PF00673.21 GAN09614.1 - 3.4e-21 75.2 0.0 1.1e-20 73.6 0.0 2.0 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAN09614.1 - 1.3e-19 70.3 0.0 2.9e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 zf-RING_UBOX PF13445.6 GAN09614.1 - 3.1e-07 30.3 3.7 3.1e-07 30.3 3.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAN09614.1 - 3.5e-07 30.0 8.7 6e-07 29.2 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN09614.1 - 6.4e-07 29.2 8.3 1.6e-06 27.9 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAN09614.1 - 9.5e-07 28.9 8.5 2e-06 27.8 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAN09614.1 - 2.4e-06 27.3 8.9 5.3e-06 26.2 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN09614.1 - 4.7e-06 26.3 8.7 9.4e-06 25.4 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN09614.1 - 1.8e-05 25.0 10.3 3.7e-05 24.0 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAN09614.1 - 0.0019 18.0 8.2 0.0054 16.6 8.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GAN09614.1 - 0.017 14.9 5.3 0.043 13.6 5.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAN09614.1 - 0.13 12.6 5.1 0.37 11.1 5.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 GAN09614.1 - 0.53 10.4 3.5 1.2 9.4 3.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 CotH PF08757.11 GAN09615.1 - 3.7e-40 138.4 0.1 5.4e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 CotH kinase protein CotH PF08757.11 GAN09616.1 - 2.1e-44 152.4 2.4 3.1e-44 151.8 2.4 1.1 1 0 0 1 1 1 1 CotH kinase protein PDZ_5 PF17817.1 GAN09617.1 - 0.00013 22.2 0.3 0.00031 21.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain DUF3299 PF11736.8 GAN09617.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) zf-RING_2 PF13639.6 GAN09618.1 - 1.1e-05 25.7 6.7 1.1e-05 25.7 6.7 2.1 2 0 0 2 2 2 1 Ring finger domain RINGv PF12906.7 GAN09618.1 - 0.00054 20.0 6.7 0.0011 19.1 6.7 1.5 1 0 0 1 1 1 1 RING-variant domain SWIM PF04434.17 GAN09618.1 - 0.0013 18.3 1.0 0.0031 17.1 1.0 1.7 1 1 0 1 1 1 1 SWIM zinc finger zf-RING_UBOX PF13445.6 GAN09618.1 - 0.0039 17.2 3.9 0.0039 17.2 3.9 1.7 2 0 0 2 2 1 1 RING-type zinc-finger C1_1 PF00130.22 GAN09618.1 - 0.017 15.0 2.5 0.017 15.0 2.5 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 GAN09618.1 - 0.026 14.1 4.6 0.047 13.3 4.6 1.4 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 GAN09618.1 - 0.069 13.3 2.9 0.14 12.3 2.9 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 GAN09618.1 - 0.13 12.3 5.7 0.044 13.7 2.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 AT_hook PF02178.19 GAN09618.1 - 0.13 12.2 5.8 0.59 10.2 5.8 2.2 1 0 0 1 1 1 0 AT hook motif PHD PF00628.29 GAN09618.1 - 0.37 10.7 7.6 0.72 9.8 7.6 1.5 1 0 0 1 1 1 0 PHD-finger FYVE PF01363.21 GAN09618.1 - 2.3 8.4 10.9 0.045 13.9 2.3 2.3 2 0 0 2 2 2 0 FYVE zinc finger GAGA_bind PF06217.12 GAN09618.1 - 4 7.6 9.8 7 6.8 9.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Ribosomal_L2 PF00181.23 GAN09621.1 - 2e-10 40.4 0.1 3e-10 39.9 0.1 1.3 1 1 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MAS20 PF02064.15 GAN09622.1 - 1.2e-40 138.6 0.9 1.2e-40 138.6 0.9 1.7 2 0 0 2 2 2 1 MAS20 protein import receptor SET PF00856.28 GAN09622.1 - 0.00065 20.1 2.6 0.00065 20.1 2.6 2.2 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 GAN09622.1 - 0.0037 17.3 13.7 0.0058 16.7 13.7 1.3 1 0 0 1 1 1 1 MYND finger ARF7EP_C PF14949.6 GAN09622.1 - 0.008 16.8 3.1 0.008 16.8 3.1 2.4 2 0 0 2 2 2 1 ARF7 effector protein C-terminus YajC PF02699.15 GAN09622.1 - 0.08 12.8 4.0 0.29 11.0 0.1 3.2 3 1 0 3 3 3 0 Preprotein translocase subunit DUF2256 PF10013.9 GAN09622.1 - 0.32 11.1 5.9 0.63 10.2 5.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2691 PF10903.8 GAN09622.1 - 1.1 9.1 4.4 5.8 6.8 0.1 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2691) MAD PF05557.13 GAN09623.1 - 3.3e-24 85.2 86.4 2.8e-18 65.7 0.4 3.3 2 1 1 3 3 3 2 Mitotic checkpoint protein zf-CCCH PF00642.24 GAN09624.1 - 3.9e-12 45.7 5.2 4.2e-10 39.3 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAN09624.1 - 7.7e-06 25.8 8.5 0.0001 22.2 1.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAN09624.1 - 1.5e-05 24.7 5.4 0.00064 19.5 0.7 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAN09624.1 - 0.0018 18.7 5.9 0.17 12.4 0.7 3.1 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GAN09624.1 - 0.65 10.7 4.9 0.53 11.0 3.1 1.8 2 1 0 2 2 2 0 Torus domain DPBB_1 PF03330.18 GAN09626.1 - 6.1e-05 23.2 0.7 0.00013 22.2 0.7 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN09626.1 - 0.016 15.1 0.5 0.021 14.7 0.5 1.3 1 0 0 1 1 1 0 Barwin family zinc_ribbon_9 PF14369.6 GAN09626.1 - 0.15 12.3 0.2 0.33 11.2 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon Aminotran_1_2 PF00155.21 GAN09627.1 - 1.1e-23 84.0 0.0 2.3e-23 82.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Mtc PF03820.17 GAN09628.1 - 1.1e-108 363.0 1.0 1.2e-108 362.9 1.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NiFe_hyd_3_EhaA PF17367.2 GAN09628.1 - 0.013 15.6 0.1 0.035 14.3 0.1 1.7 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A HTH_Tnp_Tc3_2 PF01498.18 GAN09629.1 - 1.2e-11 44.6 0.2 1.5e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 Transposase Med15_fungi PF05397.12 GAN09630.1 - 2.5e-32 111.4 0.2 2.5e-32 111.4 0.2 10.9 8 4 3 12 12 12 1 Mediator complex subunit 15 6PF2K PF01591.18 GAN09631.1 - 2.6e-70 236.2 0.0 4e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAN09631.1 - 1.4e-20 73.8 0.0 3.2e-20 72.6 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAN09631.1 - 2e-05 24.8 0.0 7.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 GAN09631.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 tRNA ligase kinase domain Myb_DNA-binding PF00249.31 GAN09632.1 - 6.6e-93 304.7 52.3 4.2e-13 49.3 0.6 10.2 10 0 0 10 10 10 10 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN09632.1 - 2.5e-76 251.8 32.3 3.9e-13 49.4 0.1 9.7 6 3 4 10 10 10 9 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAN09632.1 - 4.1e-11 42.6 17.5 0.0033 17.3 0.0 7.2 5 2 3 8 8 8 4 Myb DNA-binding like SLIDE PF09111.10 GAN09632.1 - 2.2e-10 40.5 4.8 0.0023 18.0 0.2 6.7 4 2 2 7 7 7 3 SLIDE Myb_DNA-bind_4 PF13837.6 GAN09632.1 - 0.0012 19.1 33.6 0.18 12.2 0.5 7.9 7 2 0 7 7 7 4 Myb/SANT-like DNA-binding domain Imm51 PF15595.6 GAN09632.1 - 0.0014 18.6 0.5 3.1 7.8 0.0 4.1 4 0 0 4 4 4 2 Immunity protein 51 Rap1_C PF11626.8 GAN09632.1 - 0.0038 17.3 17.4 0.047 13.8 0.2 5.9 3 2 3 6 6 6 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 GAN09632.1 - 0.015 15.5 20.2 5.6 7.2 0.0 6.6 5 1 1 7 7 7 0 SANT/Myb-like domain of DAMP1 DUF4490 PF14892.6 GAN09632.1 - 0.13 12.4 0.2 18 5.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4490) DUF1664 PF07889.12 GAN09633.1 - 0.023 14.7 0.2 0.023 14.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAN09633.1 - 0.028 14.4 1.0 0.12 12.4 0.0 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ArAE_2_N PF10337.9 GAN09633.1 - 0.27 10.2 2.4 0.34 9.9 2.4 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Atg14 PF10186.9 GAN09633.1 - 0.69 8.9 17.8 0.12 11.4 14.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4047 PF13256.6 GAN09633.1 - 4.5 7.5 11.9 32 4.7 10.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) Occludin_ELL PF07303.13 GAN09633.1 - 5 7.9 20.9 3.4 8.5 8.2 3.5 2 1 1 3 3 3 0 Occludin homology domain HSA PF07529.13 GAN09634.1 - 5.1e-16 58.7 1.2 5.1e-16 58.7 1.2 5.0 6 0 0 6 6 6 1 HSA Myb_DNA-bind_6 PF13921.6 GAN09634.1 - 1.9e-07 31.3 0.3 6.7e-07 29.5 0.3 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAN09634.1 - 0.0077 16.4 0.3 0.016 15.4 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Hydrolase_6 PF13344.6 GAN09635.1 - 4.3e-28 97.4 0.0 7e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN09635.1 - 2.1e-15 56.5 0.0 4.7e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAN09635.1 - 3.2e-05 24.3 0.0 7.6e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN09635.1 - 9.3e-05 22.6 0.0 0.0095 16.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase LtrA PF06772.11 GAN09636.1 - 1.5e-38 132.9 21.4 1.5e-38 132.9 21.4 1.6 1 1 1 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) ASFV_J13L PF05568.11 GAN09636.1 - 0.0038 17.0 0.3 0.0038 17.0 0.3 2.4 2 0 0 2 2 2 1 African swine fever virus J13L protein Umbravirus_LDM PF04817.12 GAN09636.1 - 0.66 9.3 10.7 0.26 10.6 5.1 2.2 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family B12D PF06522.11 GAN09637.1 - 6.3e-21 73.9 0.1 7.8e-21 73.7 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit HpcH_HpaI PF03328.14 GAN09638.1 - 3.1e-54 183.4 1.4 3.1e-54 183.4 1.4 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 GAN09638.1 - 1.4e-19 70.5 0.0 3.3e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 GAN09638.1 - 0.0015 17.5 0.6 0.0026 16.7 0.6 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain ECH_1 PF00378.20 GAN09639.1 - 2.3e-56 190.9 0.0 2.7e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN09639.1 - 1.1e-25 90.8 0.0 2e-23 83.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase RRM_1 PF00076.22 GAN09640.1 - 1.5e-86 284.2 3.4 3.1e-21 74.9 0.3 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAN09640.1 - 4.9e-29 100.3 1.9 2.4e-28 98.1 1.7 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAN09640.1 - 2.1e-14 53.2 0.1 0.029 14.0 0.0 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN09640.1 - 1.4e-06 28.3 0.7 0.43 10.7 0.0 5.0 3 2 1 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GAN09640.1 - 1e-05 25.4 1.2 2.7 8.1 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 GAN09640.1 - 0.00027 20.6 2.9 2 8.2 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain DUF4523 PF15023.6 GAN09640.1 - 0.0017 18.2 0.0 37 4.1 0.0 4.2 3 1 0 4 4 4 0 Protein of unknown function (DUF4523) RRM_3 PF08777.11 GAN09640.1 - 0.016 15.3 14.9 0.11 12.5 2.4 4.3 4 1 1 5 5 4 0 RNA binding motif SET_assoc PF11767.8 GAN09640.1 - 0.024 14.3 0.1 9 6.0 0.0 3.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RE_Eco29kI PF09517.10 GAN09640.1 - 0.095 12.3 2.7 2.1 8.0 0.1 3.1 3 0 0 3 3 3 0 Eco29kI restriction endonuclease DUF1318 PF07027.12 GAN09640.1 - 3.4 8.2 10.8 11 6.6 1.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1318) Suf PF05843.14 GAN09641.1 - 0.69 9.8 5.1 0.83 9.6 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SWIRM-assoc_2 PF16496.5 GAN09642.1 - 0.81 8.5 7.6 0.93 8.3 7.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Presenilin PF01080.17 GAN09642.1 - 3.7 6.2 5.2 4.1 6.1 5.2 1.0 1 0 0 1 1 1 0 Presenilin DUF423 PF04241.15 GAN09643.1 - 3.2e-22 78.5 0.2 4.1e-22 78.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Peptidase_M41 PF01434.18 GAN09644.1 - 2e-66 223.5 0.0 2.9e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAN09644.1 - 4.9e-44 150.0 0.0 8.7e-43 145.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN09644.1 - 1.4e-13 50.4 0.1 4.2e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 GAN09644.1 - 8.7e-06 26.1 0.1 2.8e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 FtsH Extracellular RuvB_N PF05496.12 GAN09644.1 - 0.0025 17.6 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAN09644.1 - 0.0028 16.9 0.1 0.0046 16.2 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 GAN09644.1 - 0.0047 16.9 0.0 0.019 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAN09644.1 - 0.005 17.1 0.1 0.7 10.2 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAN09644.1 - 0.0095 16.3 0.8 0.26 11.7 0.2 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 GAN09644.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 GAN09644.1 - 0.015 15.7 0.3 0.042 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAN09644.1 - 0.069 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAN09644.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI adh_short PF00106.25 GAN09645.1 - 2.9e-30 105.2 0.1 2.5e-29 102.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN09645.1 - 2.9e-17 63.0 0.0 3.5e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAN09645.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAN09645.1 - 1.2e-06 28.6 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAN09645.1 - 0.029 13.8 0.1 0.091 12.1 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sirohm_synth_C PF14823.6 GAN09645.1 - 0.08 12.6 0.1 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Glyco_hydro_9 PF00759.19 GAN09646.1 - 1.6e-99 334.2 10.8 2.1e-99 333.8 10.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 VPDSG-CTERM PF18205.1 GAN09646.1 - 0.018 14.9 1.1 0.018 14.9 1.1 2.4 3 0 0 3 3 3 0 VPDSG-CTERM motif UPF0172 PF03665.13 GAN09647.1 - 1.4e-50 172.0 0.3 1.7e-50 171.8 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 GAN09647.1 - 5.1e-05 23.2 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Lectin_leg-like PF03388.13 GAN09648.1 - 5.3e-55 186.3 0.2 7.7e-55 185.7 0.2 1.2 1 0 0 1 1 1 1 Legume-like lectin family ABC_tran_CTD PF16326.5 GAN09648.1 - 0.034 14.4 1.1 0.034 14.4 1.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 GAN09648.1 - 0.039 14.0 1.0 0.067 13.2 1.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OATP PF03137.20 GAN09648.1 - 0.16 10.2 0.0 0.25 9.6 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CCDC53 PF10152.9 GAN09648.1 - 0.31 11.4 2.6 0.28 11.6 0.4 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Mt_ATP-synt_D PF05873.12 GAN09648.1 - 0.88 9.4 4.5 3 7.7 0.7 2.4 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) ARGLU PF15346.6 GAN09648.1 - 1.7 8.5 13.3 3.8 7.4 2.3 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 HIP1_clath_bdg PF16515.5 GAN09648.1 - 3.7 8.2 15.7 4.4 8.0 4.9 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C3HC4_3 PF13920.6 GAN09649.1 - 0.0015 18.4 8.1 0.0024 17.7 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SUIM_assoc PF16619.5 GAN09649.1 - 0.07 13.2 13.1 0.63 10.1 8.1 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C4H2 PF10146.9 GAN09649.1 - 0.27 11.5 14.1 1.1 9.6 2.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein RLL PF10036.9 GAN09649.1 - 0.58 10.0 7.6 0.3 10.9 4.8 1.8 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein zf-B_box PF00643.24 GAN09649.1 - 0.75 10.0 6.4 0.4 10.9 3.2 2.1 2 0 0 2 2 2 0 B-box zinc finger Zn_ribbon_SprT PF17283.2 GAN09650.1 - 0.022 14.6 2.3 0.58 10.1 0.5 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain ATC_hydrolase PF14196.6 GAN09650.1 - 0.032 15.0 0.0 0.037 14.8 0.0 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF3818 PF12825.7 GAN09651.1 - 4.2e-94 315.4 8.3 1.1e-93 314.0 8.3 1.7 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 GAN09651.1 - 1.8e-14 53.8 2.7 4.3e-13 49.4 2.7 2.8 1 1 0 1 1 1 1 PX-associated PX PF00787.24 GAN09651.1 - 2.5e-08 33.9 3.1 5.9e-08 32.7 1.3 2.7 2 1 0 2 2 2 1 PX domain HTH_23 PF13384.6 GAN09652.1 - 1.6e-07 30.9 0.2 5.9e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 GAN09652.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Rap1_C PF11626.8 GAN09652.1 - 0.0017 18.4 0.1 0.0028 17.7 0.1 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_6 PF13921.6 GAN09652.1 - 0.0067 16.6 1.1 0.013 15.7 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain HTH_28 PF13518.6 GAN09652.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-binding PF00249.31 GAN09652.1 - 0.13 12.4 1.1 0.27 11.5 1.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Prefoldin PF02996.17 GAN09653.1 - 0.027 14.4 9.5 0.26 11.2 0.8 3.4 2 1 0 3 3 3 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 GAN09653.1 - 0.055 13.7 12.4 0.67 10.2 3.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FAD_SOX PF18371.1 GAN09653.1 - 0.12 12.8 0.8 0.35 11.3 0.1 2.1 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF1664 PF07889.12 GAN09653.1 - 0.12 12.4 7.2 0.38 10.8 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DrsE PF02635.15 GAN09653.1 - 0.12 12.7 1.0 0.31 11.4 0.4 2.1 1 1 1 2 2 2 0 DsrE/DsrF-like family FliD_N PF02465.18 GAN09653.1 - 0.13 13.0 0.4 0.13 13.0 0.4 2.7 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus Toxin_32 PF08120.11 GAN09653.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Tamulustoxin family Snapin_Pallidin PF14712.6 GAN09653.1 - 0.2 12.1 12.4 0.18 12.2 0.5 3.7 2 2 1 3 3 3 0 Snapin/Pallidin GIT_CC PF16559.5 GAN09653.1 - 0.22 11.4 6.9 2.3 8.2 0.8 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3209 PF11483.8 GAN09653.1 - 0.26 11.7 2.0 2.4 8.6 0.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3209) DUF4600 PF15372.6 GAN09653.1 - 0.28 11.6 11.7 0.12 12.9 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) KASH_CCD PF14662.6 GAN09653.1 - 0.48 10.2 23.5 0.081 12.8 5.8 3.4 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH HCMV_UL139 PF12507.8 GAN09653.1 - 0.55 10.6 4.2 0.18 12.2 0.4 2.2 3 0 0 3 3 3 0 Human Cytomegalovirus UL139 protein ZapB PF06005.12 GAN09653.1 - 1.3 9.6 18.6 0.51 10.8 2.7 2.9 3 0 0 3 3 3 0 Cell division protein ZapB DUF641 PF04859.12 GAN09653.1 - 1.3 9.4 6.6 1.2 9.5 0.8 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CLZ PF16526.5 GAN09653.1 - 1.9 8.9 16.3 5.5 7.4 1.4 4.6 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5595 PF18077.1 GAN09653.1 - 2.1 8.5 5.4 10 6.3 0.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) BLOC1_2 PF10046.9 GAN09653.1 - 2.7 8.3 13.5 0.12 12.7 3.1 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.18 GAN09653.1 - 3.4 8.0 10.4 0.23 11.8 1.8 2.9 3 0 0 3 3 2 0 TSC-22/dip/bun family YabA PF06156.13 GAN09653.1 - 3.8 8.2 14.4 0.6 10.8 2.4 2.9 1 1 1 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 GAN09653.1 - 4.8 7.3 20.1 0.66 10.1 3.7 3.3 1 1 1 3 3 3 0 Tropomyosin like CorA PF01544.18 GAN09653.1 - 7.1 5.9 13.1 0.61 9.3 3.9 2.5 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 GAN09653.1 - 7.5 6.6 14.2 1.9 8.5 0.9 3.6 2 1 2 4 4 4 0 Prefoldin subunit DivIC PF04977.15 GAN09653.1 - 8.4 6.2 10.7 12 5.8 2.7 3.2 2 2 1 3 3 3 0 Septum formation initiator Spc24 PF08286.11 GAN09653.1 - 8.7 6.6 14.3 16 5.8 4.2 3.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 PTR2 PF00854.21 GAN09654.1 - 1.2e-90 304.3 5.4 2.1e-90 303.4 5.4 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 GAN09654.1 - 2.4e-11 43.2 23.9 3.5e-08 32.8 10.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAN09654.1 - 0.0067 14.8 1.8 0.0067 14.8 1.8 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CCB1 PF12046.8 GAN09654.1 - 0.096 12.0 0.4 0.36 10.2 0.4 2.0 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B PTR2 PF00854.21 GAN09655.1 - 6.2e-93 311.8 4.0 6.9e-93 311.6 2.9 1.6 1 1 0 1 1 1 1 POT family PIF1 PF05970.14 GAN09656.1 - 3.4e-48 164.7 1.8 1.7e-41 142.6 0.2 3.0 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GAN09656.1 - 3.1e-21 76.0 0.0 4.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN09656.1 - 1.1e-08 35.5 0.1 3e-08 34.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAN09656.1 - 0.00015 21.4 0.1 0.00036 20.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 GAN09656.1 - 0.00047 20.4 1.3 0.0018 18.6 0.5 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 GAN09656.1 - 0.002 18.6 0.2 0.0046 17.4 0.2 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 GAN09656.1 - 0.0032 15.5 5.8 0.013 13.4 0.0 2.4 2 1 1 3 3 3 1 Helicase Viral_helicase1 PF01443.18 GAN09656.1 - 0.0056 16.5 1.4 0.41 10.4 0.6 3.2 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 GAN09656.1 - 0.011 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAN09656.1 - 0.019 15.5 1.7 0.044 14.3 0.3 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 GAN09656.1 - 0.029 14.8 0.6 0.15 12.4 0.2 2.5 2 1 0 2 2 2 0 RNA helicase DUF815 PF05673.13 GAN09656.1 - 0.042 13.0 0.1 0.075 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAN09656.1 - 0.055 13.9 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 GAN09656.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD_C_2 PF13538.6 GAN09656.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain TsaE PF02367.17 GAN09656.1 - 0.1 12.6 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 GAN09656.1 - 0.12 12.1 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 GAN09656.1 - 0.17 10.8 0.3 0.28 10.1 0.3 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RdRP PF05183.12 GAN09657.1 - 8.2e-113 378.1 0.3 1.1e-112 377.7 0.3 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 GAN09657.1 - 0.037 13.8 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.23 GAN09658.1 - 9.8e-10 37.7 0.1 5.3e-09 35.3 0.0 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain zf-GRF PF06839.12 GAN09658.1 - 1.7e-05 24.8 6.6 3.6e-05 23.8 6.6 1.6 1 0 0 1 1 1 1 GRF zinc finger zf-primase PF09329.11 GAN09659.1 - 1.8e-10 40.5 2.4 3.4e-10 39.6 2.4 1.5 1 0 0 1 1 1 1 Primase zinc finger Cyclin_N PF00134.23 GAN09660.1 - 5.9e-06 26.0 0.3 1.2e-05 25.0 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN09660.1 - 0.0039 17.6 0.1 0.0039 17.6 0.1 2.7 3 0 0 3 3 3 1 Cyclin HSP70 PF00012.20 GAN09661.1 - 1e-264 879.3 13.6 1.2e-264 879.1 13.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN09661.1 - 1.6e-14 53.5 6.7 6.3e-13 48.2 2.7 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GAN09661.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAN09661.1 - 0.00079 19.8 6.6 2.3 8.7 0.6 4.0 3 1 0 3 3 3 2 Cell division protein FtsA Edc3_linker PF16598.5 GAN09662.1 - 4.6 8.0 12.1 0.48 11.1 7.3 1.7 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 Ubiquitin_2 PF14560.6 GAN09663.1 - 1.9e-27 95.5 0.1 3.8e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 GAN09663.1 - 6.4e-26 90.2 1.3 8.6e-26 89.8 0.7 1.5 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.23 GAN09663.1 - 0.00038 20.2 0.1 0.002 17.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family AAA-ATPase_like PF09820.9 GAN09663.1 - 0.017 14.5 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase Adhesin_P1_N PF18652.1 GAN09663.1 - 0.033 14.2 1.0 0.059 13.4 0.3 1.9 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain RRM_1 PF00076.22 GAN09664.1 - 1.4e-13 50.4 0.0 2.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN09664.1 - 0.0058 16.7 1.6 0.0085 16.1 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 GAN09664.1 - 0.12 12.5 0.1 0.66 10.1 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 GAN09664.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Presenilin PF01080.17 GAN09664.1 - 0.27 10.0 3.1 0.29 9.8 3.1 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GAN09664.1 - 0.57 9.0 7.4 0.67 8.7 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Amino_oxidase PF01593.24 GAN09666.1 - 1.2e-29 103.9 0.0 1.4e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAN09666.1 - 5.8e-10 39.3 0.0 1.7e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAN09666.1 - 5.8e-08 32.7 0.1 4.6e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAN09666.1 - 0.0002 20.7 0.9 0.00042 19.6 0.3 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 GAN09666.1 - 0.00021 21.8 0.4 0.019 15.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAN09666.1 - 0.0036 16.6 0.0 0.007 15.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN09666.1 - 0.0067 16.4 0.1 0.054 13.5 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 GAN09666.1 - 0.014 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 GAN09666.1 - 0.039 12.8 0.2 0.057 12.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 GAN09666.1 - 0.076 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAN09666.1 - 0.092 11.8 0.5 0.51 9.4 0.3 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAN09666.1 - 0.16 11.0 0.3 0.25 10.4 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain T6SS_VasJ PF16989.5 GAN09666.1 - 0.28 10.6 0.0 0.43 10.0 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ zf-H2C2_2 PF13465.6 GAN09667.1 - 1.9e-11 43.8 17.8 1.7e-06 28.2 3.9 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 GAN09667.1 - 3.9e-10 39.6 16.7 7.1e-06 26.2 3.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN09667.1 - 0.00017 22.1 15.4 0.0088 16.8 2.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 GAN09667.1 - 0.0064 17.1 3.5 0.0064 17.1 3.5 1.9 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 GAN09667.1 - 0.041 14.2 0.8 0.041 14.2 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 GAN09667.1 - 0.052 13.8 3.4 0.17 12.2 3.4 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 GAN09667.1 - 0.27 11.0 11.7 0.47 10.2 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 GAN09667.1 - 1.1 9.7 4.5 4.9 7.7 0.1 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 GAN09667.1 - 1.7 9.0 9.9 0.38 11.1 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ATG7_N PF16420.5 GAN09668.1 - 1.2e-82 277.9 0.3 1.9e-82 277.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 GAN09668.1 - 7.7e-46 156.4 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 GAN09668.1 - 0.017 15.1 0.1 0.44 10.6 0.0 2.6 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase MAAL_C PF07476.11 GAN09669.1 - 0.07 12.3 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Spb1_C PF07780.12 GAN09670.1 - 7.3e-76 254.5 29.5 7.3e-76 254.5 29.5 4.5 4 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 GAN09670.1 - 4.5e-57 193.0 0.1 1.1e-56 191.7 0.1 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 GAN09670.1 - 1.4e-44 151.8 18.2 1.4e-44 151.8 18.2 6.1 3 2 2 5 5 5 1 Domain of unknown function (DUF3381) Kei1 PF08552.11 GAN09671.1 - 0.16 11.8 1.5 0.44 10.4 1.5 1.7 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Folate_carrier PF01770.18 GAN09671.1 - 0.53 9.0 1.9 0.84 8.3 1.9 1.3 1 0 0 1 1 1 0 Reduced folate carrier AAA_2 PF07724.14 GAN09672.1 - 6.6e-54 182.6 5.7 9e-51 172.4 0.0 3.2 4 0 0 4 4 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAN09672.1 - 2.8e-34 117.1 1.6 2.8e-34 117.1 1.6 3.3 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 GAN09672.1 - 1.7e-26 93.2 0.1 4.7e-14 53.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAN09672.1 - 5.3e-24 84.1 0.1 5.3e-24 84.1 0.1 3.1 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAN09672.1 - 2.1e-20 73.1 1.9 5.7e-12 45.8 0.0 4.1 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 GAN09672.1 - 4.7e-19 68.2 0.0 1.2e-08 34.9 0.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 GAN09672.1 - 8.9e-14 52.2 0.8 2.9e-07 31.0 0.1 4.7 4 1 0 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 GAN09672.1 - 8.3e-10 38.6 0.1 3.1e-06 27.0 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 GAN09672.1 - 4.4e-08 32.8 1.0 2.9e-05 23.6 0.0 3.7 3 1 0 3 3 2 1 Bacterial TniB protein AAA_22 PF13401.6 GAN09672.1 - 5.4e-08 33.2 0.1 0.017 15.4 0.0 3.9 3 2 0 3 3 2 2 AAA domain AAA_7 PF12775.7 GAN09672.1 - 5.7e-08 32.5 0.0 0.00053 19.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAN09672.1 - 9.8e-08 31.6 0.0 0.0049 16.3 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAN09672.1 - 1.4e-07 31.6 0.1 0.012 15.6 0.0 3.8 4 1 0 4 4 2 2 AAA domain IstB_IS21 PF01695.17 GAN09672.1 - 3.4e-07 30.2 0.0 0.032 13.9 0.0 2.9 2 1 0 2 2 2 2 IstB-like ATP binding protein Roc PF08477.13 GAN09672.1 - 6.6e-05 23.1 0.0 0.74 10.0 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 GAN09672.1 - 6.9e-05 22.1 0.5 0.47 9.6 0.1 3.4 2 2 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 GAN09672.1 - 0.00011 22.2 0.0 0.024 14.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain EzrA PF06160.12 GAN09672.1 - 0.00017 19.9 12.4 0.0003 19.1 12.4 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA RNA_helicase PF00910.22 GAN09672.1 - 0.00023 21.5 0.0 1 9.8 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Torsin PF06309.11 GAN09672.1 - 0.00052 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Torsin AAA_24 PF13479.6 GAN09672.1 - 0.00072 19.3 0.0 0.48 10.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 GAN09672.1 - 0.00074 19.5 0.0 1 9.4 0.0 2.9 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 GAN09672.1 - 0.00087 19.1 4.8 1.3 8.8 0.3 4.3 3 1 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAN09672.1 - 0.0011 19.6 6.6 0.3 11.6 0.0 4.0 3 2 0 3 3 2 2 AAA domain ABC_tran PF00005.27 GAN09672.1 - 0.0011 19.5 0.1 0.42 11.1 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 GAN09672.1 - 0.0012 19.1 0.1 5.8 7.1 0.0 4.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 GAN09672.1 - 0.0024 17.8 0.0 3.4 7.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 GAN09672.1 - 0.005 17.0 0.4 3.8 7.7 0.0 3.6 5 0 0 5 5 2 1 AAA domain AAA_3 PF07726.11 GAN09672.1 - 0.008 16.0 0.0 2.6 7.9 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GAN09672.1 - 0.0095 16.0 0.0 0.86 9.6 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAN09672.1 - 0.01 15.6 0.0 1.5 8.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAN09672.1 - 0.011 15.3 0.0 1.3 8.6 0.0 3.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 GAN09672.1 - 0.012 15.5 0.0 0.93 9.2 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein BLOC1_2 PF10046.9 GAN09672.1 - 0.012 15.9 3.8 0.012 15.9 3.8 2.4 2 1 1 3 3 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_23 PF13476.6 GAN09672.1 - 0.016 15.7 2.0 0.016 15.7 2.0 4.5 4 1 0 4 4 4 0 AAA domain AAA_19 PF13245.6 GAN09672.1 - 0.016 15.5 0.0 0.34 11.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAN09672.1 - 0.021 14.8 0.3 4.8 7.1 0.0 3.4 4 0 0 4 4 3 0 NTPase AAA_25 PF13481.6 GAN09672.1 - 0.023 14.3 1.3 1 8.9 0.0 3.5 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 GAN09672.1 - 0.034 13.9 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 GAN09672.1 - 0.11 12.4 14.9 1.2 9.0 0.1 5.4 3 2 3 6 6 5 0 ATPase domain predominantly from Archaea Tup_N PF08581.10 GAN09672.1 - 1 9.7 8.4 0.088 13.1 1.7 2.8 3 0 0 3 3 1 0 Tup N-terminal DASH_Spc19 PF08287.11 GAN09672.1 - 1 9.2 12.2 2 8.3 8.9 2.6 2 1 0 2 2 2 0 Spc19 FlxA PF14282.6 GAN09672.1 - 5.8 7.0 7.7 13 5.8 2.1 2.4 1 1 1 2 2 2 0 FlxA-like protein UAA PF08449.11 GAN09673.1 - 2.4e-51 174.7 14.9 2.8e-51 174.5 14.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAN09673.1 - 6.9e-13 49.0 12.1 1.7e-09 37.9 4.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAN09673.1 - 0.0028 16.9 5.8 0.11 11.6 0.1 3.1 1 1 2 3 3 3 2 Nucleotide-sugar transporter InvH PF04741.12 GAN09673.1 - 0.041 13.8 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein TPT PF03151.16 GAN09673.1 - 0.12 11.7 8.1 0.39 10.0 8.1 1.7 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF805 PF05656.14 GAN09674.1 - 0.018 15.5 1.6 0.06 13.8 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) ANAPC4_WD40 PF12894.7 GAN09675.1 - 3.1e-18 65.9 8.1 2.1e-06 27.9 0.3 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAN09675.1 - 1.2e-12 48.1 29.6 7.7e-06 26.6 1.0 7.2 7 1 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAN09675.1 - 1.9e-07 30.4 0.1 4.8e-06 25.8 0.0 2.8 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Menin PF05053.13 GAN09675.1 - 1.3 7.3 6.8 1.8 6.9 6.8 1.2 1 0 0 1 1 1 0 Menin Gly_acyl_tr_N PF06021.11 GAN09675.1 - 3 7.9 9.5 0.55 10.3 4.5 2.0 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase NARP1 PF12569.8 GAN09677.1 - 1.3e-176 588.6 25.6 1.3e-176 588.6 25.6 2.3 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 GAN09677.1 - 4.5e-14 51.4 35.3 8.3e-05 22.4 2.0 10.3 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAN09677.1 - 1.4e-13 50.4 9.4 0.57 11.2 0.0 10.4 8 4 4 12 12 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN09677.1 - 1e-12 48.4 25.3 0.07 13.6 0.0 8.7 8 2 1 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAN09677.1 - 1.4e-09 38.5 9.4 6 7.6 0.2 9.1 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN09677.1 - 1.1e-08 34.8 11.8 0.11 12.9 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN09677.1 - 1.2e-07 31.8 0.9 0.059 13.5 0.0 5.4 6 1 1 7 7 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAN09677.1 - 2.6e-07 30.3 0.9 0.12 12.0 0.0 3.7 3 0 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_1 PF00515.28 GAN09677.1 - 1.5e-06 27.7 21.3 0.0086 15.9 3.3 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN09677.1 - 4.9e-06 26.3 32.8 0.0087 16.2 1.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN09677.1 - 4.9e-05 22.9 15.7 0.0019 17.9 1.8 6.4 5 1 0 5 5 5 1 TPR repeat TPR_12 PF13424.6 GAN09677.1 - 6.6e-05 23.1 12.8 0.77 10.1 0.2 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN09677.1 - 0.00015 21.1 13.8 0.0024 17.1 0.1 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN09677.1 - 0.00083 19.8 10.0 1.9 9.3 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN09677.1 - 0.0014 18.5 1.0 0.62 10.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAN09677.1 - 0.088 13.5 0.1 4.5 8.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 GAN09678.1 - 8.6e-25 87.3 0.0 2.1e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain COMPASS-Shg1 PF05205.12 GAN09679.1 - 9.1e-17 61.6 1.4 1.1e-16 61.3 1.4 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 F-box PF00646.33 GAN09681.1 - 0.0006 19.6 0.3 0.002 17.9 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAN09681.1 - 0.0031 17.4 1.6 0.0063 16.4 0.4 2.2 2 0 0 2 2 2 1 F-box-like KdpD PF02702.17 GAN09681.1 - 0.13 11.8 0.1 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain LRR_4 PF12799.7 GAN09681.1 - 0.95 10.0 11.9 65 4.2 0.5 6.0 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) FTR1 PF03239.14 GAN09682.1 - 6.1e-70 235.8 16.3 7.3e-70 235.6 16.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family MgtE PF01769.16 GAN09682.1 - 0.96 9.8 17.1 2 8.8 1.2 2.9 3 0 0 3 3 3 0 Divalent cation transporter Cu-oxidase_2 PF07731.14 GAN09683.1 - 1.5e-41 141.3 8.8 5.7e-40 136.2 0.4 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAN09683.1 - 3.2e-39 133.6 16.5 2.4e-38 130.8 1.6 4.2 3 3 1 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 GAN09683.1 - 4.3e-30 104.9 1.7 7.4e-29 100.9 0.3 3.4 4 0 0 4 4 4 1 Multicopper oxidase Hexokinase_2 PF03727.16 GAN09684.1 - 7.4e-67 225.3 0.0 9.6e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN09684.1 - 2.1e-59 200.8 0.0 2.8e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.32 GAN09685.1 - 1.2e-28 98.7 6.8 1.5e-05 25.6 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09685.1 - 3.5e-08 33.6 0.0 0.81 10.0 0.0 6.1 3 1 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAN09685.1 - 0.0046 15.5 0.0 0.098 11.2 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 GAN09685.1 - 0.0099 14.9 1.1 6.9 5.5 0.0 3.7 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 GAN09685.1 - 0.14 12.7 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 PQQ-like domain BBS2_Mid PF14783.6 GAN09685.1 - 0.18 11.8 0.2 15 5.7 0.0 3.6 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region SNF2_N PF00176.23 GAN09686.1 - 2.9e-59 200.5 4.7 7.5e-59 199.2 4.6 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN09686.1 - 1.1e-22 80.5 0.2 3.1e-20 72.6 0.1 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAN09686.1 - 1.5e-07 31.6 3.4 8e-07 29.2 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAN09686.1 - 1e-06 28.1 0.3 4.6e-06 26.0 0.3 2.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 GAN09686.1 - 0.025 14.8 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HATPase_c PF02518.26 GAN09687.1 - 4.9e-28 97.9 0.0 2.5e-26 92.4 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAN09687.1 - 5.1e-23 81.4 1.6 2.9e-14 53.2 0.5 2.6 1 1 1 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 GAN09687.1 - 4.2e-15 55.5 1.9 1.3e-14 53.9 1.9 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain FMO-like PF00743.19 GAN09688.1 - 4.3e-15 55.1 0.6 2e-12 46.3 0.5 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAN09688.1 - 8.3e-12 44.9 0.2 1.1e-09 37.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAN09688.1 - 1.4e-09 38.0 0.1 2.5e-08 34.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN09688.1 - 2.1e-09 37.1 0.0 1.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN09688.1 - 4.2e-07 29.5 0.2 2.6e-05 23.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAN09688.1 - 0.0031 17.1 0.4 0.48 9.9 0.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAN09688.1 - 0.0043 16.3 0.2 0.067 12.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 GAN09688.1 - 0.009 15.1 0.1 0.22 10.5 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAN09688.1 - 0.06 12.0 0.7 0.35 9.5 0.3 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 GAN09688.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAN09688.1 - 0.092 13.3 0.0 11 6.6 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAN09688.1 - 0.098 11.9 0.0 1.8 7.8 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 GAN09688.1 - 0.29 11.1 2.1 15 5.5 0.1 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAN09688.1 - 4.4 6.3 5.3 0.26 10.3 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain LRR_4 PF12799.7 GAN09689.1 - 1.1e-35 121.0 60.2 3.5e-05 24.1 1.6 12.0 7 3 2 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAN09689.1 - 5.3e-33 112.6 57.4 4.6e-08 32.7 3.1 9.9 5 3 6 11 11 11 10 Leucine rich repeat LRR_9 PF14580.6 GAN09689.1 - 5.4e-11 42.3 22.4 0.00035 20.1 1.1 5.6 2 2 2 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 GAN09689.1 - 9e-10 37.8 41.2 0.21 11.7 0.1 13.1 14 0 0 14 14 14 5 Leucine Rich repeat LRR_1 PF00560.33 GAN09689.1 - 7.2e-09 35.0 37.7 11 7.0 0.1 14.5 14 2 0 14 14 14 3 Leucine Rich Repeat Chlorovi_GP_rpt PF06598.11 GAN09689.1 - 0.48 10.5 2.1 9.4 6.4 0.1 3.1 3 0 0 3 3 3 0 Chlorovirus glycoprotein repeat KH_1 PF00013.29 GAN09690.1 - 1.9e-18 66.0 4.6 6.6e-06 25.9 0.0 8.0 8 0 0 8 8 8 5 KH domain VP9 PF09625.10 GAN09690.1 - 0.09 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 VP9 protein ALS_ss_C PF10369.9 GAN09690.1 - 0.43 10.8 1.8 1 9.6 0.1 2.5 3 0 0 3 3 3 0 Small subunit of acetolactate synthase UBN_AB PF14075.6 GAN09691.1 - 0.039 13.7 1.4 0.13 11.9 1.4 2.0 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Ribosomal_S4e PF00900.20 GAN09691.1 - 0.075 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Ribosomal family S4e DUF2183 PF09949.9 GAN09692.1 - 3.1e-31 107.6 1.0 7.6e-31 106.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) FAM184 PF15665.5 GAN09692.1 - 1.8 8.3 33.0 0.034 13.9 25.4 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Rootletin PF15035.6 GAN09692.1 - 2.1 8.3 25.9 22 5.0 25.8 2.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.7 GAN09692.1 - 4.2 7.5 35.3 0.41 10.8 9.9 2.8 1 1 1 2 2 2 0 Tropomyosin like Amidohydro_2 PF04909.14 GAN09693.1 - 6.9e-08 32.6 0.0 9.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 GAN09693.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAN09693.1 - 0.037 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family TGT PF01702.18 GAN09694.1 - 3e-80 270.0 0.0 3.7e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Polysacc_deac_1 PF01522.21 GAN09696.1 - 5.1e-29 100.7 0.0 9.6e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF515 PF04415.12 GAN09696.1 - 8.6 4.6 7.6 15 3.8 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) NAD_binding_10 PF13460.6 GAN09697.1 - 3.2e-15 56.5 0.0 5.9e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN09697.1 - 7.3e-13 48.6 0.0 1.9e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 GAN09697.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 GAN09697.1 - 0.01 15.3 0.0 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Shikimate_DH PF01488.20 GAN09697.1 - 0.015 15.4 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 GAN09697.1 - 0.055 12.9 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 GAN09697.1 - 0.067 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3268 PF11672.8 GAN09697.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 zinc-finger-containing domain GDP_Man_Dehyd PF16363.5 GAN09697.1 - 0.15 11.5 0.0 1.3 8.3 0.0 2.1 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase MMM1 PF10296.9 GAN09698.1 - 7.9e-05 21.9 0.0 0.00026 20.1 0.0 2.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ATP_sub_h PF10775.9 GAN09699.1 - 0.0037 17.2 0.1 0.015 15.3 0.1 2.1 1 0 0 1 1 1 1 ATP synthase complex subunit h OmpH PF03938.14 GAN09699.1 - 0.0052 17.1 16.5 0.0052 17.1 16.5 3.2 2 1 1 3 3 3 1 Outer membrane protein (OmpH-like) FUSC PF04632.12 GAN09699.1 - 4.6 5.6 8.7 6.7 5.1 8.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sel1 PF08238.12 GAN09700.1 - 1.3e-31 108.3 18.5 5e-06 27.0 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat Mito_carr PF00153.27 GAN09701.1 - 1.4e-66 220.5 1.7 2.9e-21 75.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RabGAP-TBC PF00566.18 GAN09702.1 - 5.3e-51 173.3 0.2 5.3e-51 173.3 0.2 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AAA_5 PF07728.14 GAN09704.1 - 8.8e-89 294.6 0.0 2.8e-35 121.3 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN09704.1 - 6.1e-09 36.5 3.0 0.039 14.3 0.1 5.3 3 2 1 5 5 5 2 AAA ATPase domain CbbQ_C PF08406.10 GAN09704.1 - 2.3e-06 27.8 0.1 0.001 19.3 0.1 2.8 2 0 0 2 2 2 1 CbbQ/NirQ/NorQ C-terminal AAA_3 PF07726.11 GAN09704.1 - 2.3e-05 24.3 0.1 1 9.2 0.0 3.8 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) MCM6_C PF18263.1 GAN09704.1 - 0.0058 16.8 0.4 0.29 11.4 0.0 3.3 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain AAA_22 PF13401.6 GAN09704.1 - 0.0073 16.6 1.8 9.7 6.5 0.0 4.1 3 2 0 3 3 3 2 AAA domain RuvB_N PF05496.12 GAN09704.1 - 0.043 13.6 0.1 0.26 11.0 0.1 2.4 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 GAN09704.1 - 0.047 13.7 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAN09704.1 - 0.11 12.9 0.0 4.8 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 GAN09704.1 - 0.11 11.8 0.6 9.1 5.6 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Csm2_III-A PF03750.13 GAN09704.1 - 0.13 13.1 0.6 0.56 11.1 0.4 2.2 2 0 0 2 2 1 0 Csm2 Type III-A Roc PF08477.13 GAN09704.1 - 0.19 11.9 0.5 33 4.7 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RhoGAP PF00620.27 GAN09705.1 - 8.3e-49 165.3 0.0 1.8e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 GAN09705.1 - 1.9e-15 57.3 0.3 5.1e-15 55.9 0.3 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 GAN09705.1 - 3.1e-14 52.3 1.0 8.6e-14 50.9 1.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN09705.1 - 2e-12 46.8 0.1 6.6e-12 45.1 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain PH_9 PF15410.6 GAN09705.1 - 7.3e-11 42.5 0.1 2.4e-10 40.8 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain WW PF00397.26 GAN09705.1 - 7.8e-11 41.9 1.5 1.7e-10 40.8 1.5 1.6 1 0 0 1 1 1 1 WW domain SH3_2 PF07653.17 GAN09705.1 - 4.3e-10 39.1 0.1 1.4e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain PQQ PF01011.21 GAN09705.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat TTD PF12148.8 GAN09705.1 - 0.061 13.2 0.1 0.25 11.2 0.1 1.9 1 1 0 1 1 1 0 Tandem tudor domain within UHRF1 Rax2 PF12768.7 GAN09707.1 - 1.7e-28 99.6 11.1 4.2e-26 91.8 0.0 5.2 5 3 2 7 7 7 2 Cortical protein marker for cell polarity SH3_9 PF14604.6 GAN09707.1 - 3.4e-06 26.8 0.1 6.9e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN09707.1 - 0.00074 19.1 0.1 0.0013 18.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Kelch_6 PF13964.6 GAN09707.1 - 0.0068 16.7 0.7 78 3.8 0.1 5.2 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 GAN09707.1 - 0.15 11.6 1.1 6.8 6.4 0.0 4.1 4 0 0 4 4 4 0 Kelch motif DUF5122 PF17164.4 GAN09707.1 - 0.64 10.4 0.0 0.64 10.4 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller zf-C2H2 PF00096.26 GAN09708.1 - 5.3e-05 23.4 22.4 0.00032 21.0 2.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type SR-25 PF10500.9 GAN09708.1 - 0.0023 17.6 2.9 0.0023 17.6 2.9 2.9 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein zf-H2C2_2 PF13465.6 GAN09708.1 - 0.016 15.6 3.9 0.016 15.6 3.9 4.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 GAN09708.1 - 0.028 14.7 20.1 0.26 11.6 3.0 3.9 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 GAN09708.1 - 0.56 11.2 18.6 1.4 9.9 1.6 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger SUIM_assoc PF16619.5 GAN09708.1 - 3.8 7.6 26.8 0.71 10.0 3.4 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF719 PF05334.13 GAN09708.1 - 7.3 6.7 7.7 1.3 9.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF719) Fumble PF03630.14 GAN09710.1 - 1.4e-133 445.2 0.3 2.1e-133 444.6 0.3 1.3 1 0 0 1 1 1 1 Fumble Tyr_Deacylase PF02580.16 GAN09710.1 - 0.017 15.6 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase DUF727 PF05303.12 GAN09711.1 - 3.9e-11 42.9 0.1 1.3e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF727) GNVR PF13807.6 GAN09711.1 - 0.065 13.2 0.2 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Aa_trans PF01490.18 GAN09712.1 - 6e-62 209.7 21.8 7.1e-62 209.4 21.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAN09712.1 - 0.62 9.0 19.3 0.01 14.9 9.4 2.0 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family Med21 PF11221.8 GAN09713.1 - 2.2e-34 118.8 9.5 2.9e-34 118.4 9.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 GAN09713.1 - 0.0096 16.0 1.9 0.0096 16.0 1.9 2.1 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 MCPsignal PF00015.21 GAN09713.1 - 0.048 13.5 5.2 0.061 13.1 4.5 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HIP1_clath_bdg PF16515.5 GAN09713.1 - 0.28 11.8 12.3 0.26 11.9 3.3 2.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PCRF PF03462.18 GAN09713.1 - 0.82 9.5 8.4 0.97 9.3 7.8 1.4 1 1 0 1 1 1 0 PCRF domain Peptidase_M18 PF02127.15 GAN09714.1 - 2.8e-171 570.1 0.1 3.2e-171 569.9 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAN09714.1 - 1.6e-08 33.9 1.2 1.3e-06 27.6 0.4 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase DnaJ PF00226.31 GAN09715.1 - 1.3e-25 89.3 1.2 2.5e-25 88.4 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 GAN09715.1 - 6.2e-12 45.7 25.1 3.4e-09 36.8 12.4 2.5 1 1 0 2 2 2 2 Transmembrane Fragile-X-F protein DUF3742 PF12553.8 GAN09715.1 - 0.05 13.7 1.4 0.71 10.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Orf78 PF06024.12 GAN09715.1 - 0.29 11.5 8.4 2.4 8.5 0.1 3.6 3 1 0 3 3 3 0 Orf78 (ac78) Abhydrolase_9_N PF15420.6 GAN09715.1 - 0.32 11.0 4.5 0.12 12.3 0.6 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus CoA_binding_3 PF13727.6 GAN09715.1 - 6.2 6.8 7.8 0.3 11.1 1.3 2.1 2 0 0 2 2 2 0 CoA-binding domain ADK PF00406.22 GAN09716.1 - 2.4e-47 160.8 0.0 3.3e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAN09716.1 - 8e-23 81.4 0.0 1.4e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAN09716.1 - 2.4e-13 49.8 0.0 4.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAN09716.1 - 4.5e-07 30.5 0.0 7.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN09716.1 - 0.00022 21.4 0.0 0.00075 19.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAN09716.1 - 0.009 16.3 0.0 0.019 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAN09716.1 - 0.096 12.0 0.1 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Mucin-like PF16058.5 GAN09717.1 - 0.11 12.6 8.9 0.051 13.7 4.0 2.3 2 0 0 2 2 2 0 Mucin-like DUF3719 PF12516.8 GAN09717.1 - 0.17 11.6 0.3 0.65 9.7 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) ABC_tran PF00005.27 GAN09718.1 - 3.5e-45 153.9 0.3 1.6e-21 77.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAN09718.1 - 1.2e-20 73.3 4.0 1.2e-20 73.3 4.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 GAN09718.1 - 7.6e-19 68.6 4.1 0.0014 18.5 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAN09718.1 - 2.9e-09 36.7 3.2 0.011 15.1 0.2 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAN09718.1 - 1e-08 34.8 0.1 0.0041 16.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 GAN09718.1 - 7.3e-08 32.6 2.5 0.0019 18.3 0.2 3.9 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 GAN09718.1 - 9e-08 32.8 2.2 0.068 13.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAN09718.1 - 9.8e-08 32.6 0.0 0.00098 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAN09718.1 - 3.8e-07 30.5 0.0 0.0014 18.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAN09718.1 - 1.2e-06 28.6 4.1 0.048 13.4 0.0 3.7 3 1 0 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 GAN09718.1 - 2.2e-06 28.0 0.0 0.015 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAN09718.1 - 2.7e-06 27.6 0.0 0.067 13.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 GAN09718.1 - 9e-06 25.7 0.5 0.052 13.5 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 GAN09718.1 - 2.2e-05 25.0 0.2 0.26 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 GAN09718.1 - 3.7e-05 23.5 0.4 0.2 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 GAN09718.1 - 4.7e-05 23.4 0.0 0.3 11.2 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 GAN09718.1 - 0.00016 22.0 0.0 0.59 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 GAN09718.1 - 0.00024 21.1 0.0 3.7 7.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 GAN09718.1 - 0.00066 19.6 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.6 GAN09718.1 - 0.00072 20.0 0.1 0.14 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 GAN09718.1 - 0.00084 19.0 0.0 1.7 8.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 GAN09718.1 - 0.00093 18.2 0.0 0.75 8.7 0.0 2.7 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 GAN09718.1 - 0.0013 18.5 0.0 0.56 9.9 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 GAN09718.1 - 0.0022 18.4 0.1 0.6 10.5 0.0 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) EIIA-man PF03610.16 GAN09718.1 - 0.0043 17.3 0.5 0.037 14.3 0.2 2.5 2 0 0 2 2 2 1 PTS system fructose IIA component AAA_25 PF13481.6 GAN09718.1 - 0.0078 15.8 0.0 1.6 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 GAN09718.1 - 0.0085 16.3 0.0 1.2 9.4 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit VirE PF05272.11 GAN09718.1 - 0.013 15.2 0.1 3.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E DUF87 PF01935.17 GAN09718.1 - 0.013 15.6 1.6 4.4 7.3 0.0 3.2 3 1 0 3 3 3 0 Helicase HerA, central domain AAA_5 PF07728.14 GAN09718.1 - 0.019 15.0 0.1 11 6.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 GAN09718.1 - 0.021 14.3 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 GAN09718.1 - 0.031 14.0 0.1 8.9 6.0 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 GAN09718.1 - 0.035 14.1 0.1 2.7 8.0 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 GAN09718.1 - 0.036 13.4 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 GAN09718.1 - 0.037 14.2 0.0 5.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAN09718.1 - 0.037 13.2 2.2 7.8 5.5 0.4 3.2 1 1 1 3 3 3 0 G-protein alpha subunit Septin PF00735.18 GAN09718.1 - 0.041 13.2 0.0 7.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 GAN09718.1 - 0.046 13.5 0.1 7.7 6.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 GAN09718.1 - 0.046 13.5 0.0 0.58 9.9 0.0 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein cobW PF02492.19 GAN09718.1 - 0.047 13.3 0.0 7.9 6.0 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAN09718.1 - 0.048 12.9 0.0 3.1 6.9 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 GAN09718.1 - 0.058 12.7 0.1 0.64 9.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 GAN09718.1 - 0.099 12.3 0.8 7.9 6.1 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 GAN09718.1 - 0.1 11.6 0.0 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 GAN09718.1 - 0.11 12.0 0.0 3.2 7.2 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAN09718.1 - 0.14 12.1 0.1 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 NTPase GIY-YIG PF01541.24 GAN09719.1 - 1.3e-13 51.0 0.1 2.6e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 GAN09719.1 - 0.35 11.1 3.6 0.83 9.9 3.6 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Pkinase PF00069.25 GAN09720.1 - 8.6e-69 231.8 0.0 1.1e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09720.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN09720.1 - 2e-05 23.8 0.0 2.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAN09720.1 - 3.4e-05 23.3 0.1 0.0001 21.8 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN09720.1 - 0.00065 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAN09720.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAN09720.1 - 0.039 13.3 0.0 0.2 10.9 0.0 1.9 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.22 GAN09720.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YqeY PF09424.10 GAN09721.1 - 3.6e-37 127.6 1.9 4.2e-37 127.4 1.9 1.0 1 0 0 1 1 1 1 Yqey-like protein DUF773 PF05600.12 GAN09721.1 - 0.0025 16.6 0.1 0.003 16.4 0.1 1.1 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Fanconi_A_N PF15865.5 GAN09721.1 - 0.043 13.2 0.1 0.049 13.0 0.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Bclx_interact PF08945.10 GAN09721.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain RabGAP-TBC PF00566.18 GAN09723.1 - 6e-45 153.5 2.8 6e-45 153.5 2.8 2.2 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 GAN09723.1 - 0.0035 16.8 0.0 0.012 15.1 0.0 1.9 1 1 0 1 1 1 1 Rab-binding domain (RBD) MBOAT PF03062.19 GAN09724.1 - 2.1e-34 119.4 30.7 1e-33 117.1 30.7 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAN09724.1 - 0.00012 22.3 2.8 0.00038 20.7 2.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Vps8 PF12816.7 GAN09726.1 - 3e-68 229.2 0.9 5.6e-67 225.1 0.0 3.0 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 GAN09726.1 - 1.5e-07 31.3 2.2 0.0022 17.8 0.1 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-rbx1 PF12678.7 GAN09726.1 - 0.00045 20.4 2.3 0.0012 19.1 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAN09726.1 - 0.0016 18.8 1.8 0.0016 18.8 1.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAN09726.1 - 0.0047 16.8 4.3 0.013 15.5 4.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAN09726.1 - 0.0048 16.7 2.3 0.0048 16.7 2.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 GAN09726.1 - 0.01 16.7 0.2 0.073 14.0 0.2 2.6 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 GAN09726.1 - 0.036 13.9 2.0 0.11 12.4 2.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN09726.1 - 0.13 12.1 0.9 0.41 10.4 0.9 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 GAN09726.1 - 1.3 9.0 5.7 0.56 10.1 2.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ACOX PF01756.19 GAN09727.1 - 3.5e-50 170.1 0.0 6.3e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAN09727.1 - 2.4e-20 72.5 0.0 5.1e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 GAN09727.1 - 4.5e-16 59.5 0.1 1.1e-15 58.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 GAN09727.1 - 1.5e-08 34.9 0.4 1.3e-07 32.0 0.4 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Vps53_N PF04100.12 GAN09728.1 - 4.3e-112 374.8 14.9 8.6e-112 373.9 14.9 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 GAN09728.1 - 9.3e-07 28.9 4.4 5.8e-06 26.3 0.0 3.1 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 GAN09728.1 - 9e-05 21.9 10.2 9e-05 21.9 10.2 2.3 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 GAN09728.1 - 0.00049 20.3 3.4 0.00049 20.3 3.4 2.3 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Spc7 PF08317.11 GAN09728.1 - 0.0035 16.3 13.2 0.0035 16.3 13.2 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein COG2 PF06148.11 GAN09728.1 - 0.016 15.3 10.3 0.32 11.1 6.8 3.8 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.12 GAN09728.1 - 0.026 13.1 1.0 0.042 12.4 1.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF489 PF04356.12 GAN09728.1 - 0.041 13.9 10.1 9.4 6.2 8.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF489) EF-G-binding_N PF07299.11 GAN09728.1 - 0.31 11.6 3.7 2.7 8.6 0.4 3.8 4 0 0 4 4 3 0 Elongation factor G-binding protein, N-terminal Goodbye PF17109.5 GAN09728.1 - 0.34 11.4 8.6 45 4.5 0.1 5.0 3 2 1 4 4 4 0 fungal STAND N-terminal Goodbye domain Sigma70_ner PF04546.13 GAN09728.1 - 0.38 10.6 12.6 99 2.7 12.6 2.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Laminin_II PF06009.12 GAN09728.1 - 0.81 9.7 12.6 0.19 11.7 5.8 2.6 1 1 1 2 2 2 0 Laminin Domain II RSS_P20 PF11757.8 GAN09728.1 - 0.87 10.1 5.7 1.5 9.3 1.9 3.3 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF1759 PF03564.15 GAN09728.1 - 1.8 8.5 7.4 22 5.0 0.5 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1759) DUF2203 PF09969.9 GAN09728.1 - 4 8.2 9.0 2.3 9.0 2.0 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec20 PF03908.13 GAN09728.1 - 4.4 7.3 9.0 5.8 6.9 5.8 2.9 2 0 0 2 2 2 0 Sec20 Spectrin PF00435.21 GAN09728.1 - 7 7.2 11.0 6.8 7.2 7.5 2.6 1 1 2 3 3 3 0 Spectrin repeat Occludin_ELL PF07303.13 GAN09728.1 - 7.2 7.4 12.9 4.5 8.0 1.9 3.6 2 1 1 3 3 3 0 Occludin homology domain DUF948 PF06103.11 GAN09728.1 - 7.3 6.9 9.8 2.5 8.4 1.7 3.1 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 GAN09728.1 - 8.3 6.8 16.3 13 6.2 6.5 4.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 GAN09728.1 - 8.4 6.7 10.3 1.2 9.4 1.8 3.0 3 0 0 3 3 2 0 Haemolysin XhlA APG6_N PF17675.1 GAN09728.1 - 9.2 6.8 11.3 21 5.7 10.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Pkinase PF00069.25 GAN09729.1 - 2.9e-68 230.1 0.1 7.8e-68 228.7 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09729.1 - 4.5e-38 131.0 0.0 1.2e-37 129.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAN09729.1 - 1.9e-20 72.4 0.2 3.2e-20 71.6 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 GAN09729.1 - 5.2e-06 26.0 0.0 9.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN09729.1 - 0.0002 20.4 0.1 0.00043 19.3 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAN09729.1 - 0.00036 20.5 0.1 0.06 13.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAN09729.1 - 0.00063 19.2 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAN09729.1 - 0.0077 15.9 0.6 0.021 14.4 0.6 1.7 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 GAN09729.1 - 0.1 12.1 0.5 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL HSP70 PF00012.20 GAN09730.1 - 6.4e-07 27.9 0.0 2.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein C2 PF00168.30 GAN09731.1 - 1.5e-18 67.0 0.1 4e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 GAN09731.1 - 5.4e-13 49.4 3.6 1.3e-11 44.9 1.4 3.8 3 2 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 GAN09731.1 - 4.9e-10 38.6 0.1 1.6e-05 23.7 0.0 3.8 3 0 0 3 3 3 2 Plant family of unknown function (DUF810) DUF5398 PF17376.2 GAN09731.1 - 0.16 12.6 0.6 0.67 10.6 0.6 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5398) T2SS_PulS_OutS PF09691.10 GAN09731.1 - 1.2 9.3 3.7 0.97 9.6 0.3 2.6 2 0 0 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) Mito_carr PF00153.27 GAN09732.1 - 5.1e-48 161.0 4.4 2e-18 66.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 GAN09732.1 - 0.0023 18.1 1.9 0.65 10.3 0.0 3.5 2 1 1 3 3 3 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Sugar_tr PF00083.24 GAN09734.1 - 3.3e-120 402.0 27.4 3.9e-120 401.8 27.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN09734.1 - 5.6e-21 74.8 24.2 5.6e-21 74.8 24.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DnaJ_C PF01556.18 GAN09735.1 - 4.4e-40 137.2 0.8 6.2e-40 136.7 0.8 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN09735.1 - 4.8e-27 93.9 1.2 9.5e-27 92.9 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 GAN09735.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein Brix PF04427.18 GAN09736.1 - 1.8e-39 135.9 0.0 2.6e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain GDA1_CD39 PF01150.17 GAN09737.1 - 3.6e-119 398.2 0.0 5.1e-119 397.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EamA PF00892.20 GAN09738.1 - 5.8e-13 49.2 37.1 2.4e-06 27.8 18.2 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 GAN09738.1 - 0.00016 21.3 14.8 0.0079 15.7 13.1 2.9 2 1 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 GAN09738.1 - 0.015 14.6 7.2 0.012 14.8 3.6 2.3 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport DUF3188 PF11384.8 GAN09738.1 - 0.8 9.5 0.0 0.8 9.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) GCP_C_terminal PF04130.13 GAN09739.1 - 4.2e-76 256.4 13.0 4.2e-76 256.4 13.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAN09739.1 - 7.5e-74 249.1 0.8 7.5e-74 249.1 0.8 1.8 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal ArsC PF03960.15 GAN09739.1 - 0.37 10.8 1.3 6.6 6.8 0.1 3.0 3 0 0 3 3 3 0 ArsC family Ras PF00071.22 GAN09740.1 - 1.3e-60 203.7 0.1 1.5e-60 203.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN09740.1 - 1.4e-35 122.1 0.1 4e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN09740.1 - 1.7e-13 50.4 0.1 1.9e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN09740.1 - 8.1e-06 25.9 0.0 2.1e-05 24.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN09740.1 - 1.7e-05 24.8 0.7 0.17 11.8 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 GAN09740.1 - 2.9e-05 23.6 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAN09740.1 - 0.00025 20.6 0.0 0.00064 19.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAN09740.1 - 0.0027 18.1 0.2 0.0057 17.1 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 GAN09740.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 GAN09740.1 - 0.023 14.1 0.1 0.055 12.9 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAN09740.1 - 0.1 11.7 0.1 0.34 10.0 0.1 1.9 1 1 0 1 1 1 0 G-protein alpha subunit SET PF00856.28 GAN09741.1 - 3.7e-12 46.9 0.3 3.6e-11 43.8 0.3 2.1 1 1 0 1 1 1 1 SET domain YHS PF04945.13 GAN09741.1 - 0.031 14.4 0.8 0.088 12.9 0.8 1.7 1 0 0 1 1 1 0 YHS domain NAD_binding_10 PF13460.6 GAN09742.1 - 7.3e-12 45.5 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN09742.1 - 5.5e-07 29.4 0.0 7.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family UQ_con PF00179.26 GAN09743.1 - 8.3e-55 184.3 0.0 9.4e-55 184.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAN09743.1 - 0.0025 18.1 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GAN09743.1 - 0.0086 15.8 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAN09743.1 - 0.057 13.3 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain WD40 PF00400.32 GAN09744.1 - 3.1e-17 62.6 1.0 0.00024 21.9 0.0 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09744.1 - 1.6e-07 31.5 0.0 1.3 9.4 0.0 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN09744.1 - 0.0064 15.2 0.1 0.32 9.6 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Hydantoinase_B PF02538.14 GAN09745.1 - 5.2e-216 718.0 0.2 7.4e-216 717.5 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAN09745.1 - 2.1e-102 342.3 0.2 4.5e-101 337.9 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAN09745.1 - 3.5e-61 206.0 0.3 2.3e-58 196.8 0.0 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Coprogen_oxidas PF01218.18 GAN09746.1 - 7.6e-138 458.2 0.1 9e-138 458.0 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Brr6_like_C_C PF10104.9 GAN09747.1 - 2.9e-28 98.3 0.5 4.4e-28 97.7 0.5 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Cyt-b5 PF00173.28 GAN09749.1 - 2e-24 85.5 0.2 2.7e-24 85.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PDGLE PF13190.6 GAN09749.1 - 0.17 11.8 0.5 0.25 11.2 0.5 1.4 1 1 0 1 1 1 0 PDGLE domain ECH_1 PF00378.20 GAN09752.1 - 2.6e-49 167.8 0.1 3.2e-49 167.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN09752.1 - 4.1e-35 121.9 0.1 4.8e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SAM_2 PF07647.17 GAN09753.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN09753.1 - 0.029 14.8 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) IGR PF09597.10 GAN09753.1 - 0.077 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif UPF0160 PF03690.13 GAN09755.1 - 9.9e-133 442.7 0.0 1.1e-132 442.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Utp14 PF04615.13 GAN09756.1 - 0.054 12.1 29.8 0.1 11.2 29.8 1.4 1 0 0 1 1 1 0 Utp14 protein Gram_pos_anchor PF00746.21 GAN09756.1 - 0.098 12.6 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif EphA2_TM PF14575.6 GAN09756.1 - 0.2 12.6 3.6 0.87 10.5 0.0 3.5 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain V-ATPase_G PF03179.15 GAN09756.1 - 0.22 12.1 9.6 0.8 10.3 9.6 1.9 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit TFIIF_alpha PF05793.12 GAN09756.1 - 2.6 6.6 48.9 0.094 11.3 42.7 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PIEZO PF15917.5 GAN09756.1 - 5.4 6.4 14.7 3.4 7.1 11.8 2.2 2 0 0 2 2 2 0 Piezo LEA_4 PF02987.16 GAN09756.1 - 9.7 6.4 11.9 2 8.6 7.6 2.1 2 1 0 2 2 2 0 Late embryogenesis abundant protein Ribosomal_L22e PF01776.17 GAN09757.1 - 1.1e-49 167.4 1.9 1.3e-49 167.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF4130 PF13566.6 GAN09758.1 - 0.037 14.1 0.7 2 8.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4130 MutS_IV PF05190.18 GAN09758.1 - 0.061 13.7 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV UCH PF00443.29 GAN09760.1 - 5.8e-52 176.7 0.8 9.1e-52 176.1 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN09760.1 - 4e-24 85.8 0.8 6.8e-24 85.0 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nucleocapsid-N PF11030.8 GAN09760.1 - 0.026 14.5 4.3 0.048 13.6 4.3 1.5 1 0 0 1 1 1 0 Nucleocapsid protein N Peptidase_C98 PF15499.6 GAN09760.1 - 0.1 12.1 10.7 0.86 9.0 0.2 3.5 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3716 PF12511.8 GAN09760.1 - 0.83 9.7 5.2 3.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) C1_1 PF00130.22 GAN09760.1 - 8.7 6.3 10.4 25 4.8 1.9 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SLC35F PF06027.12 GAN09761.1 - 2.5e-62 211.1 20.1 1.1e-50 172.8 15.4 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 GAN09761.1 - 2.4e-07 30.1 3.0 2.9e-07 29.8 2.4 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAN09761.1 - 1.7e-05 25.0 27.2 0.00037 20.7 10.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAN09761.1 - 3.7e-05 23.1 13.9 0.00053 19.3 13.9 2.1 1 1 0 1 1 1 1 UAA transporter family RseC_MucC PF04246.12 GAN09761.1 - 0.11 12.4 5.0 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LTXXQ PF07813.12 GAN09762.1 - 6.5 7.5 13.2 2.5 8.9 0.4 3.1 2 1 1 3 3 3 0 LTXXQ motif family protein TMEM171 PF15471.6 GAN09762.1 - 8.8 5.2 7.2 0.32 9.9 0.3 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 MFS_1 PF07690.16 GAN09763.1 - 1.6e-43 149.0 54.0 2.7e-36 125.2 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAN09763.1 - 6.5e-10 37.9 0.1 6.5e-10 37.9 0.1 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 GAN09763.1 - 0.0011 17.6 28.3 0.0035 16.0 6.4 3.2 2 2 1 3 3 3 3 MFS/sugar transport protein BT1 PF03092.16 GAN09763.1 - 0.005 15.1 4.9 0.57 8.3 0.2 2.4 2 0 0 2 2 2 2 BT1 family SelK_SelG PF10961.8 GAN09763.1 - 0.09 13.4 0.5 3.9 8.2 0.0 2.8 2 0 0 2 2 2 0 Selenoprotein SelK_SelG CBFD_NFYB_HMF PF00808.23 GAN09765.1 - 0.013 15.8 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DEAD PF00270.29 GAN09767.1 - 2.1e-45 154.6 0.8 4.1e-45 153.7 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN09767.1 - 6.7e-33 113.3 0.2 2.9e-31 108.1 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN09767.1 - 1.3e-05 25.3 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAN09767.1 - 0.00061 20.1 0.9 0.0052 17.1 0.4 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAN09767.1 - 0.0037 17.0 0.1 0.0075 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 GAN09767.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 GAN09767.1 - 0.016 14.0 0.2 2.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Methyltransf_23 PF13489.6 GAN09768.1 - 9.5e-21 74.3 0.1 1.3e-20 73.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN09768.1 - 3.9e-08 33.9 0.0 6.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN09768.1 - 8.8e-06 26.3 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN09768.1 - 0.00024 21.7 0.0 0.00045 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L9_N PF01281.19 GAN09768.1 - 0.15 11.6 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain ORC4_C PF14629.6 GAN09768.1 - 0.17 11.2 1.3 0.61 9.4 1.3 1.9 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus WW PF00397.26 GAN09769.1 - 5.3e-07 29.6 1.1 1.1e-06 28.6 1.1 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 GAN09769.1 - 0.013 15.5 21.0 0.013 15.5 21.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 GAN09769.1 - 0.17 11.8 11.5 0.2 11.6 11.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DGF-1_C PF11040.8 GAN09769.1 - 4.7 7.3 5.6 1.5 8.9 1.3 2.0 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Methyltransf_11 PF08241.12 GAN09770.1 - 2.2e-19 69.9 0.1 3.5e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN09770.1 - 1.9e-17 63.8 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN09770.1 - 3.3e-15 56.2 0.0 4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN09770.1 - 6.7e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAN09770.1 - 3.4e-10 39.4 0.0 4.9e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 GAN09770.1 - 2.5e-09 37.8 0.0 3.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN09770.1 - 9.6e-08 31.8 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAN09770.1 - 9.5e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 GAN09770.1 - 8.7e-05 21.9 0.1 0.00018 20.9 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 GAN09770.1 - 0.0013 18.2 0.0 0.002 17.5 0.0 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 GAN09770.1 - 0.0023 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 GAN09770.1 - 0.0039 16.8 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF3684 PF12449.8 GAN09771.1 - 3.5e-289 962.3 9.5 2.1e-284 946.4 0.4 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 GAN09771.1 - 0.00039 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 GAN09771.1 - 0.034 14.2 4.3 0.017 15.2 1.5 1.9 2 0 0 2 2 2 0 WLM domain DUF2076 PF09849.9 GAN09771.1 - 8.5 6.3 16.4 0.0089 16.1 5.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) MSA-2c PF12238.8 GAN09771.1 - 9.2 6.2 8.8 0.31 11.0 0.2 2.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c VIR_N PF15912.5 GAN09771.1 - 9.8 5.7 20.9 0.45 10.1 8.0 2.5 1 1 1 2 2 2 0 Virilizer, N-terminal NDUF_B7 PF05676.13 GAN09772.1 - 2.7e-32 110.3 4.7 3.1e-32 110.1 4.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 GAN09772.1 - 0.0019 18.2 3.5 0.0024 17.9 3.3 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX6A PF02046.15 GAN09773.1 - 3.6e-27 95.0 1.9 4.2e-27 94.8 1.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RPAP1_C PF08620.10 GAN09774.1 - 6.9e-26 90.2 1.9 1.6e-24 85.8 0.1 2.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 GAN09774.1 - 6e-09 35.5 4.7 1.9e-08 33.9 4.7 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal AAA PF00004.29 GAN09775.1 - 7.5e-06 26.4 0.6 0.0049 17.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAN09775.1 - 0.0025 17.8 0.8 0.33 10.9 0.1 3.5 1 1 0 2 2 2 1 Rad17 P-loop domain VirC2 PF07181.11 GAN09775.1 - 0.017 14.6 2.2 0.038 13.5 2.2 1.5 1 0 0 1 1 1 0 VirC2 protein TsaE PF02367.17 GAN09775.1 - 0.068 13.2 0.7 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RhoGAP PF00620.27 GAN09776.1 - 3.9e-35 120.9 1.0 1e-34 119.6 0.2 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 GAN09776.1 - 3.8e-11 43.0 20.2 3.9e-08 33.4 14.0 2.7 2 0 0 2 2 2 2 LIM domain GRDP-like PF07173.12 GAN09777.1 - 3.1e-33 115.4 24.0 2.6e-12 47.6 0.0 6.7 7 1 1 8 8 8 4 Glycine-rich domain-containing protein-like Ezh2_MCSS PF18600.1 GAN09777.1 - 0.057 13.0 2.0 2.2 7.9 0.2 2.7 2 0 0 2 2 2 0 MCSS domain Lig_chan-Glu_bd PF10613.9 GAN09777.1 - 0.082 13.1 0.1 28 5.0 0.0 2.8 3 0 0 3 3 3 0 Ligated ion channel L-glutamate- and glycine-binding site RRM_1 PF00076.22 GAN09778.1 - 1.6e-78 258.5 5.4 3e-17 62.2 0.0 5.7 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAN09778.1 - 8.5e-05 22.6 0.0 3 8.0 0.0 4.9 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.6 GAN09778.1 - 8.6e-05 22.5 0.1 2.3 8.3 0.0 4.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAN09778.1 - 0.00023 21.0 0.0 10 6.1 0.0 4.6 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_5 PF13893.6 GAN09778.1 - 0.0027 17.3 0.0 10 5.7 0.0 4.3 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutL_C PF08676.11 GAN09778.1 - 0.14 11.9 0.0 0.86 9.4 0.0 2.3 3 0 0 3 3 3 0 MutL C terminal dimerisation domain RRM_3 PF08777.11 GAN09778.1 - 0.27 11.3 8.3 14 5.8 0.0 5.7 6 0 0 6 6 6 0 RNA binding motif L51_S25_CI-B8 PF05047.16 GAN09779.1 - 4.6e-11 42.5 0.1 9.7e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sybindin PF04099.12 GAN09781.1 - 9.9e-50 168.2 1.0 1.1e-49 168.0 1.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 GAN09781.1 - 1.2e-08 35.2 0.4 1.4e-08 34.9 0.4 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2115 PF09888.9 GAN09781.1 - 0.049 14.2 0.1 0.058 13.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4790 PF16037.5 GAN09781.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) DUF5612 PF18462.1 GAN09781.1 - 0.2 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) Aminotran_1_2 PF00155.21 GAN09782.1 - 3.4e-39 135.0 0.0 9e-39 133.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAN09782.1 - 0.0082 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAN09782.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase ANF_receptor PF01094.28 GAN09783.1 - 1.5e-38 132.8 0.8 2.3e-38 132.2 0.8 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 GAN09783.1 - 2.1e-35 122.6 27.0 3.3e-35 121.9 27.0 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 GAN09783.1 - 4e-15 56.3 3.0 6.6e-15 55.6 3.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein WD40 PF00400.32 GAN09784.1 - 4.8e-15 55.7 16.5 0.037 14.9 0.5 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09784.1 - 4e-06 27.0 1.9 0.091 13.1 0.3 4.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 GAN09784.1 - 0.064 13.5 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain YpjP PF14005.6 GAN09784.1 - 1 9.4 4.9 1.4 9.0 0.8 2.9 2 0 0 2 2 2 0 YpjP-like protein Pkinase PF00069.25 GAN09785.1 - 2.1e-20 73.2 0.0 4.8e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09785.1 - 4.3e-17 62.3 0.0 9.6e-17 61.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 GAN09785.1 - 0.00098 18.8 0.3 0.0016 18.1 0.3 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 GAN09785.1 - 0.045 12.7 0.2 0.097 11.6 0.2 1.5 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 GAN09785.1 - 0.051 13.5 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family SHMT PF00464.19 GAN09786.1 - 8.1e-174 577.9 0.0 1.7e-173 576.8 0.0 1.5 2 0 0 2 2 2 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAN09786.1 - 0.00017 21.0 0.0 0.00058 19.2 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAN09786.1 - 0.00042 19.6 0.0 0.0013 18.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II DUF4142 PF13628.6 GAN09786.1 - 0.032 14.5 0.4 0.074 13.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Macro PF01661.21 GAN09786.1 - 0.042 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Macro domain Sulfate_transp PF00916.20 GAN09787.1 - 1e-97 327.3 16.1 1e-97 327.3 16.1 1.2 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAN09787.1 - 4.6e-20 71.4 0.0 7.7e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAN09787.1 - 8.3e-05 22.9 4.5 8.3e-05 22.9 4.5 3.2 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily DUF2254 PF10011.9 GAN09787.1 - 0.0021 16.9 3.8 0.0041 16.0 3.8 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Fumarate_red_C PF02300.17 GAN09787.1 - 2.7 8.1 6.2 4.8 7.3 0.2 3.0 3 0 0 3 3 3 0 Fumarate reductase subunit C MAPEG PF01124.18 GAN09788.1 - 5.3e-22 78.1 0.3 6e-22 77.9 0.3 1.0 1 0 0 1 1 1 1 MAPEG family Lipase_GDSL PF00657.22 GAN09790.1 - 1.6e-15 57.6 0.3 3.8e-15 56.4 0.1 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase LRR_4 PF12799.7 GAN09790.1 - 3.6e-09 36.8 11.9 1.1e-06 28.8 3.2 3.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAN09790.1 - 2.1e-07 30.6 5.2 2.1e-07 30.6 5.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat Lipase_GDSL_2 PF13472.6 GAN09790.1 - 1.5e-05 25.5 0.1 2.7e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-FCS PF06467.14 GAN09790.1 - 0.0045 16.9 1.0 0.012 15.5 1.0 1.8 1 1 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif LRR_9 PF14580.6 GAN09790.1 - 0.033 13.7 1.3 0.071 12.6 1.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 GAN09790.1 - 5.2 8.0 6.5 15 6.6 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat Ribosomal_L19e PF01280.20 GAN09791.1 - 3.2e-61 205.6 9.5 3.2e-61 205.6 9.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e Alpha_TIF PF02232.15 GAN09791.1 - 0.046 12.8 0.8 0.059 12.5 0.8 1.3 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) SpoIIE PF07228.12 GAN09792.1 - 2.9e-14 53.5 0.0 4.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAN09792.1 - 1.3e-11 44.7 0.0 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAN09792.1 - 1.1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C COBRA1 PF06209.13 GAN09793.1 - 4.5e-44 151.1 5.8 1e-43 149.9 5.8 1.5 1 1 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) DUF3176 PF11374.8 GAN09793.1 - 0.14 12.4 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) GTP_EFTU PF00009.27 GAN09794.1 - 1.7e-57 194.1 0.0 3.3e-57 193.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAN09794.1 - 2.1e-15 56.5 0.0 9.6e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 GAN09794.1 - 3e-09 36.8 0.1 6.6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GAN09794.1 - 9.4e-08 32.3 0.0 2.8e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 GAN09794.1 - 0.0025 17.6 0.0 0.015 15.1 0.0 2.5 2 1 0 2 2 2 1 Elongation factor G, domain IV zf-UBP PF02148.19 GAN09795.1 - 0.0027 18.0 3.4 0.007 16.7 3.4 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUSP PF06337.12 GAN09795.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 DUSP domain DUF3736 PF12540.8 GAN09796.1 - 3.1 7.9 12.2 0.13 12.4 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3736) Sugar_tr PF00083.24 GAN09797.1 - 8.5e-52 176.5 23.0 1e-51 176.2 23.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN09797.1 - 1.1e-24 87.1 38.5 2.5e-23 82.6 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.22 GAN09799.1 - 2.4e-86 290.5 0.2 3e-86 290.2 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GAN09799.1 - 1.4e-21 76.4 0.1 2.9e-10 40.1 0.0 3.0 1 1 1 2 2 2 2 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAN09799.1 - 1.9e-08 34.1 0.0 3.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DAOA PF15199.6 GAN09799.1 - 0.073 13.5 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 D-amino acid oxidase activator ATP-grasp_3 PF02655.14 GAN09799.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Plk4_PB2 PF18409.1 GAN09799.1 - 0.097 13.4 0.5 13 6.5 0.0 2.9 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 PP_kinase_C_1 PF17941.1 GAN09799.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 Ribosomal_S7 PF00177.21 GAN09800.1 - 1.7e-30 105.7 1.8 1.1e-29 103.0 1.8 1.9 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e Oxysterol_BP PF01237.18 GAN09801.1 - 1.7e-87 293.7 4.2 2.4e-85 286.6 4.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein NicO PF03824.16 GAN09802.1 - 8.6e-78 261.5 14.6 1.1e-77 261.2 14.6 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein MHYT PF03707.16 GAN09802.1 - 0.071 13.3 0.5 0.071 13.3 0.5 4.3 6 0 0 6 6 6 0 Bacterial signalling protein N terminal repeat E1_DerP2_DerF2 PF02221.15 GAN09803.1 - 6.2e-14 52.6 0.0 8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAN09803.1 - 0.00021 21.7 0.0 0.00027 21.3 0.0 1.1 1 0 0 1 1 1 1 ML-like domain DUF5491 PF17595.2 GAN09803.1 - 0.038 14.3 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5491) HLH PF00010.26 GAN09804.1 - 2.6e-14 52.9 2.7 2.8e-14 52.8 0.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4468 PF14730.6 GAN09804.1 - 0.084 13.2 0.5 0.25 11.7 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold KIAA1430 PF13879.6 GAN09804.1 - 0.088 13.6 0.4 0.088 13.6 0.4 3.3 3 1 0 3 3 3 0 KIAA1430 homologue Macoilin PF09726.9 GAN09804.1 - 1.2 7.6 17.1 2 6.8 17.1 1.5 1 0 0 1 1 1 0 Macoilin family Zn_clus PF00172.18 GAN09805.1 - 0.00015 21.8 16.5 0.00024 21.2 16.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FSH1 PF03959.13 GAN09806.1 - 2.9e-56 190.5 0.0 3.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 GAN09806.1 - 0.0013 18.0 0.1 0.019 14.3 0.0 2.5 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAN09806.1 - 0.029 14.5 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.20 GAN09806.1 - 0.06 13.0 0.0 0.29 10.7 0.0 2.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold Mito_carr PF00153.27 GAN09807.1 - 4.9e-35 119.3 4.3 1.5e-12 47.3 0.3 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Nup35_RRM PF05172.13 GAN09807.1 - 1.1e-13 51.0 0.1 3.3e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 GAN09807.1 - 2.1e-07 30.8 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ank_2 PF12796.7 GAN09808.1 - 5.1e-40 135.9 4.5 1.4e-13 51.2 0.2 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN09808.1 - 1.4e-33 114.5 9.2 1.5e-05 25.2 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN09808.1 - 3.6e-32 106.8 6.8 0.0061 17.0 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 GAN09808.1 - 1.3e-30 105.3 2.7 1.8e-07 31.5 0.0 6.2 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 GAN09808.1 - 3e-22 78.0 9.2 0.091 13.2 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Plant_tran PF04827.14 GAN09808.1 - 0.0013 18.3 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein Ribosomal_L37ae PF01780.19 GAN09809.1 - 2.6e-41 139.6 13.0 2.9e-41 139.5 13.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 GAN09809.1 - 0.00097 19.2 3.2 0.0014 18.7 3.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 GAN09809.1 - 0.0015 18.5 1.8 0.0023 17.9 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 GAN09809.1 - 0.014 15.4 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 GAN09809.1 - 0.022 14.4 2.9 2.9 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 GAN09809.1 - 0.036 14.0 3.2 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 GAN09809.1 - 0.12 12.7 2.9 4.5 7.7 3.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 GAN09809.1 - 0.93 9.6 5.6 4 7.5 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 GAN09809.1 - 4.2 8.0 7.3 2.4 8.7 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Ribosomal_L29 PF00831.23 GAN09810.1 - 3.9e-14 52.4 2.1 3.9e-14 52.4 2.1 2.1 1 1 1 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.19 GAN09810.1 - 0.056 14.0 3.3 0.094 13.2 3.2 1.5 1 1 1 2 2 2 0 Ribosomal protein S9/S16 UPF0231 PF06062.11 GAN09810.1 - 0.15 12.4 0.1 0.23 11.8 0.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0231) CENP-B_N PF04218.13 GAN09810.1 - 0.4 10.3 4.6 6 6.6 0.1 3.1 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain HMG_box PF00505.19 GAN09811.1 - 1.6e-14 54.1 0.8 3.7e-14 52.9 0.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN09811.1 - 0.0022 18.6 0.3 0.0022 18.6 0.3 2.4 3 0 0 3 3 3 1 HMG-box domain MATalpha_HMGbox PF04769.12 GAN09811.1 - 0.012 14.9 0.2 0.05 12.9 0.0 1.9 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box DTHCT PF08070.11 GAN09811.1 - 0.012 16.3 3.9 2.8 8.7 1.8 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF3947 PF13135.6 GAN09811.1 - 5.4 7.3 11.9 0.14 12.4 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) HSP90 PF00183.18 GAN09812.1 - 1.1e-232 773.5 29.2 1.4e-232 773.2 29.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAN09812.1 - 8.4e-10 39.2 0.0 5.3e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAN09812.1 - 8.4e-09 35.4 0.4 4.5e-08 33.0 0.4 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 GAN09812.1 - 0.11 12.5 0.1 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN HMG_box PF00505.19 GAN09813.1 - 0.00012 22.4 2.3 0.00016 22.0 0.6 2.0 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN09813.1 - 0.0012 19.4 1.7 0.0026 18.3 1.7 1.6 1 1 0 1 1 1 1 HMG-box domain NCD1 PF04904.13 GAN09813.1 - 0.1 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) zf-C2H2 PF00096.26 GAN09814.1 - 2.6e-11 43.3 7.9 3e-07 30.5 1.0 5.7 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN09814.1 - 1.6e-06 28.2 2.6 1.6e-06 28.2 2.6 5.0 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN09814.1 - 0.00017 22.1 8.0 0.0018 18.9 0.6 5.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAN09814.1 - 0.00043 20.5 6.1 0.039 14.1 2.4 2.5 2 0 0 2 2 2 2 Aberrant zinc-finger zf-met PF12874.7 GAN09814.1 - 0.013 15.9 7.9 0.15 12.5 1.7 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 GAN09814.1 - 1 10.0 0.1 1 10.0 0.1 4.3 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 GAN09814.1 - 6.9 7.1 15.7 1.2 9.5 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Radical_SAM PF04055.21 GAN09815.1 - 1.4e-11 45.0 0.0 2.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Nup35_RRM PF05172.13 GAN09815.1 - 1.1e-10 41.3 0.0 4.8e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Fer4_14 PF13394.6 GAN09815.1 - 0.00077 19.6 1.6 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Nup35_RRM_2 PF14605.6 GAN09815.1 - 0.037 14.0 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF99 PF01949.16 GAN09815.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 Phostensin_N PF13916.6 GAN09815.1 - 0.19 12.1 1.5 0.39 11.1 1.5 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal RAB3GAP2_N PF14655.6 GAN09815.1 - 0.65 9.2 4.9 0.55 9.4 2.6 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_FG PF13634.6 GAN09815.1 - 2.3 9.1 60.1 0.15 12.9 9.1 4.2 2 1 2 4 4 4 0 Nucleoporin FG repeat region WD40 PF00400.32 GAN09816.1 - 8.6e-41 137.2 19.0 2.5e-06 28.1 0.3 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09816.1 - 4.1e-13 49.4 3.3 0.087 13.1 0.0 5.5 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN09816.1 - 4.6e-11 42.1 6.0 0.011 14.4 0.5 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 GAN09816.1 - 1.3e-08 34.5 4.1 0.0079 15.6 0.1 3.1 1 1 3 4 4 4 3 WD40-like domain F-box-like PF12937.7 GAN09816.1 - 1.2e-07 31.5 0.7 2.4e-07 30.6 0.7 1.5 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 GAN09816.1 - 6.8e-05 22.6 0.3 0.014 15.0 0.1 2.4 1 1 0 2 2 2 2 PQQ-like domain PALB2_WD40 PF16756.5 GAN09816.1 - 0.0006 18.9 4.1 0.24 10.3 0.6 3.5 1 1 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain F-box PF00646.33 GAN09816.1 - 0.001 18.9 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAN09816.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box Ge1_WD40 PF16529.5 GAN09816.1 - 0.0016 17.5 1.3 7.5 5.4 0.0 4.1 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PRANC PF09372.10 GAN09816.1 - 0.07 13.5 0.2 0.3 11.4 0.0 2.1 1 1 1 2 2 2 0 PRANC domain LHC PF00556.20 GAN09818.1 - 0.23 11.7 11.4 1.5 9.1 2.1 2.2 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Pkinase PF00069.25 GAN09819.1 - 8.9e-55 185.9 0.8 5.9e-54 183.2 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09819.1 - 3.3e-39 134.7 0.1 7.3e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 GAN09819.1 - 2.7e-05 24.3 0.2 9.6e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain MatP PF06303.12 GAN09819.1 - 0.037 14.6 11.2 0.36 11.4 0.0 4.2 5 0 0 5 5 5 0 MatP N-terminal domain DUF1759 PF03564.15 GAN09819.1 - 1 9.3 7.5 8.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) PUF PF00806.19 GAN09820.1 - 5e-66 214.8 20.4 1.8e-08 33.6 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF234 PF03008.14 GAN09820.1 - 0.24 11.9 1.2 24 5.4 0.2 3.1 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function Hydin_ADK PF17213.3 GAN09820.1 - 0.44 10.8 19.6 4.6 7.5 1.0 2.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CUE PF02845.16 GAN09821.1 - 8.9e-11 41.3 0.5 2.5e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 CUE domain G2BR PF18442.1 GAN09821.1 - 0.015 14.9 2.9 0.015 14.9 2.9 2.6 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 GAN09821.1 - 0.087 12.9 10.6 0.15 12.1 5.4 3.0 2 1 0 2 2 2 0 Ubc7p-binding region of Cue1 hDGE_amylase PF14701.6 GAN09821.1 - 0.47 9.5 4.7 0.65 9.0 4.7 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DEAD PF00270.29 GAN09822.1 - 2.7e-45 154.3 0.9 3.8e-44 150.5 0.3 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN09822.1 - 5.5e-22 78.2 0.1 7.9e-21 74.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN09822.1 - 3.2e-10 40.3 0.7 4.4e-09 36.6 0.2 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAN09822.1 - 1.9e-08 33.8 0.0 3.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 GAN09822.1 - 0.0024 18.2 0.0 0.006 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN09822.1 - 0.0044 17.3 0.4 0.016 15.5 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAN09822.1 - 0.012 15.3 0.1 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAN09822.1 - 0.02 14.3 0.0 0.061 12.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein SecA_DEAD PF07517.14 GAN09822.1 - 0.041 13.2 0.3 0.11 11.8 0.3 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_12 PF13087.6 GAN09822.1 - 0.058 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain U6-snRNA_bdg PF10596.9 GAN09822.1 - 0.1 12.5 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 AAA PF00004.29 GAN09823.1 - 7.7e-62 207.6 0.0 1.3e-43 148.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN09823.1 - 4.5e-10 39.2 1.6 4e-06 26.5 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAN09823.1 - 6e-08 33.3 4.8 0.0081 16.6 0.0 4.7 4 1 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 GAN09823.1 - 2.2e-06 28.3 0.3 0.02 15.4 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAN09823.1 - 9.5e-06 25.8 0.0 0.092 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 GAN09823.1 - 1e-05 25.3 0.0 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 GAN09823.1 - 1.7e-05 24.8 0.0 0.071 13.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAN09823.1 - 2.3e-05 24.7 1.7 0.33 11.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 GAN09823.1 - 3.6e-05 24.1 0.0 0.062 13.7 0.0 3.1 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 GAN09823.1 - 0.00014 21.9 0.0 0.019 14.9 0.0 3.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAN09823.1 - 0.00018 21.8 0.2 0.04 14.2 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 GAN09823.1 - 0.00026 20.6 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 GAN09823.1 - 0.0003 20.8 0.0 0.59 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.22 GAN09823.1 - 0.00039 19.7 0.3 0.62 9.2 0.0 3.2 4 0 0 4 4 3 2 NB-ARC domain TIP49 PF06068.13 GAN09823.1 - 0.00066 19.0 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 GAN09823.1 - 0.0015 18.3 0.0 0.0058 16.4 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 GAN09823.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 GAN09823.1 - 0.0031 16.7 0.0 2.4 7.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 GAN09823.1 - 0.0038 16.7 0.2 0.034 13.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GAN09823.1 - 0.0038 16.8 0.1 0.026 14.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAN09823.1 - 0.004 17.3 0.0 0.027 14.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 GAN09823.1 - 0.0075 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 KaiC Vps4_C PF09336.10 GAN09823.1 - 0.012 15.6 0.1 1.6 8.8 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain NACHT PF05729.12 GAN09823.1 - 0.019 14.9 0.1 1.4 8.8 0.1 2.7 3 0 0 3 3 2 0 NACHT domain AAA_17 PF13207.6 GAN09823.1 - 0.022 15.2 1.9 9.8 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 GAN09823.1 - 0.024 14.4 0.1 0.16 11.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAN09823.1 - 0.029 14.3 2.9 4.3 7.2 0.0 3.1 3 1 1 4 4 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 GAN09823.1 - 0.049 13.4 0.2 20 4.8 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase AAA_11 PF13086.6 GAN09823.1 - 0.049 13.4 1.1 2.1 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 GAN09823.1 - 0.052 13.3 0.0 0.83 9.3 0.0 2.8 4 0 0 4 4 3 0 Sigma-54 interaction domain NTPase_1 PF03266.15 GAN09823.1 - 0.081 12.8 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 GAN09823.1 - 0.084 13.4 0.2 3.1 8.3 0.0 3.0 3 0 0 3 3 3 0 ABC transporter Rad17 PF03215.15 GAN09823.1 - 0.091 12.7 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 GAN09823.1 - 0.093 12.5 0.3 14 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.16 GAN09823.1 - 0.17 11.4 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 GAN09823.1 - 1.6 9.2 4.0 66 3.9 0.0 3.4 3 1 1 4 4 4 0 AAA domain RXT2_N PF08595.11 GAN09823.1 - 3.5 7.6 8.7 0.4 10.7 1.1 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Hist_deacetyl PF00850.19 GAN09825.1 - 2.5e-84 283.4 0.0 3.1e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Sel1 PF08238.12 GAN09826.1 - 1.2e-48 162.4 17.3 1.4e-07 31.9 0.0 7.6 8 0 0 8 8 8 7 Sel1 repeat TPR_12 PF13424.6 GAN09826.1 - 0.045 14.0 0.8 1.5 9.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN09826.1 - 0.26 11.5 2.7 2 8.7 0.1 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAN09826.1 - 1.6 8.5 8.9 4.2 7.1 0.0 4.9 5 0 0 5 5 5 0 TPR repeat WH1 PF00568.23 GAN09827.1 - 4.2e-14 52.4 0.0 6.3e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 GAN09827.1 - 5.8e-10 39.4 0.4 1.1e-09 38.5 0.4 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 GAN09827.1 - 0.012 15.4 0.5 0.027 14.3 0.5 1.6 1 0 0 1 1 1 0 WH2 motif Shadoo PF14999.6 GAN09827.1 - 0.44 10.6 14.8 0.8 9.8 14.8 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PH_TFIIH PF08567.11 GAN09828.1 - 9.7e-19 67.5 0.7 1.7e-18 66.7 0.1 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 GAN09828.1 - 1.8e-17 63.1 0.3 6.8e-11 42.0 0.0 2.9 2 0 0 2 2 2 2 BSD domain FAP PF07174.11 GAN09828.1 - 0.71 9.3 11.2 1.1 8.6 11.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HSF_DNA-bind PF00447.17 GAN09829.1 - 5.8e-34 116.6 2.2 1.9e-33 115.0 2.2 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding Cdc6_C PF09079.11 GAN09829.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF2951 PF11166.8 GAN09830.1 - 0.071 13.3 2.7 0.13 12.5 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) Aldedh PF00171.22 GAN09831.1 - 1.8e-80 270.7 0.0 2.2e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAN09831.1 - 0.026 13.6 0.0 0.069 12.2 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Far-17a_AIG1 PF04750.14 GAN09832.1 - 2.8e-36 124.7 12.5 3.4e-36 124.5 12.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein 2Fe-2S_thioredx PF01257.19 GAN09833.1 - 7.1e-59 197.8 0.1 9.7e-59 197.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DAGK_cat PF00781.24 GAN09834.1 - 1.9e-20 72.8 0.1 3.9e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cupin_8 PF13621.6 GAN09835.1 - 1e-17 64.7 0.5 1e-17 64.7 0.5 1.9 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 GAN09835.1 - 1e-15 58.2 0.0 3.2e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase SCIMP PF15050.6 GAN09835.1 - 0.07 13.6 0.4 0.07 13.6 0.4 1.9 2 0 0 2 2 2 0 SCIMP protein SR-25 PF10500.9 GAN09835.1 - 0.13 11.8 21.8 0.022 14.4 13.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cupin_1 PF00190.22 GAN09835.1 - 0.16 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF4667 PF15700.5 GAN09835.1 - 0.35 10.9 13.3 0.029 14.5 8.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF3446 PF11928.8 GAN09835.1 - 2.1 8.7 15.9 4.9 7.5 15.9 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain NIBRIN_BRCT_II PF16508.5 GAN09836.1 - 3.1e-14 53.3 0.0 9.1e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FAM199X PF15814.5 GAN09836.1 - 0.026 13.6 0.3 0.042 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X WD40 PF00400.32 GAN09837.1 - 2.6e-08 34.4 15.1 0.16 12.9 0.7 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Dynein_IC2 PF11540.8 GAN09837.1 - 1.7e-05 24.7 0.3 4.9e-05 23.2 0.3 1.8 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 GAN09837.1 - 0.016 15.5 0.0 0.091 13.1 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Sec5 PF15469.6 GAN09837.1 - 0.048 13.5 3.5 0.09 12.6 3.5 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Aa_trans PF01490.18 GAN09838.1 - 4.9e-50 170.4 29.7 6.2e-50 170.1 29.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ArfGap PF01412.18 GAN09839.1 - 1.2e-35 122.1 0.0 1.2e-35 122.1 0.0 2.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf RNB PF00773.19 GAN09840.1 - 2e-67 227.9 0.4 2e-67 227.9 0.4 1.7 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 GAN09840.1 - 2.8e-21 75.3 0.0 5.9e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 GAN09840.1 - 5.4e-13 49.1 0.0 3.4e-12 46.5 0.0 2.4 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 GAN09840.1 - 0.018 14.8 0.0 0.056 13.2 0.0 1.9 1 0 0 1 1 1 0 Rrp44-like cold shock domain A_deamin PF02137.18 GAN09841.1 - 3.2e-74 250.3 0.2 3.8e-74 250.1 0.2 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Cyclin PF08613.11 GAN09842.1 - 1.1e-13 51.9 1.7 1.1e-13 51.9 0.1 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAN09842.1 - 0.0034 17.1 1.1 0.0054 16.5 0.0 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain DUF3719 PF12516.8 GAN09842.1 - 0.046 13.4 0.5 0.091 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Polysacc_deac_1 PF01522.21 GAN09843.1 - 1e-33 115.9 0.0 1.6e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN09843.1 - 0.00091 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Methyltransf_33 PF10017.9 GAN09843.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent LIG3_BRCT PF16759.5 GAN09844.1 - 0.16 12.2 3.0 3 8.2 0.3 2.7 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain CENP-S PF15630.6 GAN09845.1 - 3.9e-24 84.8 2.0 6.7e-24 84.1 2.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAN09845.1 - 2.5e-06 27.6 0.6 3e-06 27.3 0.6 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AbiTii PF18864.1 GAN09845.1 - 0.018 15.2 1.1 0.023 14.8 1.1 1.1 1 0 0 1 1 1 0 AbiTii Vac_ImportDeg PF09783.9 GAN09846.1 - 3e-58 196.2 2.7 4.1e-58 195.8 2.7 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein EFF-AFF PF14884.6 GAN09846.1 - 0.051 11.7 0.1 0.072 11.2 0.1 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen DnaJ PF00226.31 GAN09847.1 - 5.1e-20 71.4 2.2 2.1e-19 69.4 2.2 2.1 1 0 0 1 1 1 1 DnaJ domain Tom5 PF10642.9 GAN09847.1 - 7.4 6.7 5.8 26 5.0 0.1 3.3 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase SNase PF00565.17 GAN09848.1 - 2.1e-24 86.1 0.0 3.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue GLTSCR1 PF15249.6 GAN09849.1 - 8.4e-25 87.2 0.9 8.4e-25 87.2 0.9 3.9 4 1 0 4 4 4 1 Conserved region of unknown function on GLTSCR protein ODC_AZ PF02100.17 GAN09851.1 - 1e-11 44.8 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme GRAM PF02893.20 GAN09855.1 - 6.1e-25 87.3 0.2 1.9e-24 85.7 0.2 1.8 1 0 0 1 1 1 1 GRAM domain zn-ribbon_14 PF16503.5 GAN09855.1 - 8.4e-16 57.2 5.6 8.4e-16 57.2 5.6 2.7 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 GAN09855.1 - 8.9e-13 48.4 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family LSM14 PF12701.7 GAN09855.1 - 0.047 13.8 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 Scd6-like Sm domain CBM_21 PF03370.13 GAN09856.1 - 9.9e-22 77.2 1.5 9.9e-22 77.2 1.5 1.9 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAN09856.1 - 3.6e-09 37.1 0.5 1.2e-08 35.4 0.5 2.0 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) U-box PF04564.15 GAN09857.1 - 1.8e-22 79.3 0.0 3.2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 GAN09857.1 - 1.1e-12 48.5 6.3 1.1e-12 48.5 6.3 2.1 3 0 0 3 3 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 GAN09857.1 - 1.2e-12 47.0 6.7 6.7e-09 35.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAN09857.1 - 1.2e-09 37.6 5.0 0.00037 20.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN09857.1 - 1.5e-07 31.0 6.7 7.3e-05 22.7 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAN09857.1 - 1.1e-06 28.6 0.4 0.00062 20.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN09857.1 - 3.8e-05 23.3 8.9 0.00064 19.4 0.1 4.3 4 1 1 5 5 5 2 TPR repeat ANAPC3 PF12895.7 GAN09857.1 - 0.00024 21.2 0.6 0.0006 20.0 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAN09857.1 - 0.001 19.3 2.5 0.0035 17.6 0.3 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 GAN09857.1 - 0.0017 18.5 0.0 0.0074 16.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_16 PF13432.6 GAN09857.1 - 0.0023 18.5 0.0 0.9 10.2 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat POTRA PF07244.15 GAN09857.1 - 0.009 16.6 0.0 0.25 11.9 0.0 3.0 2 1 1 3 3 3 1 Surface antigen variable number repeat TPR_7 PF13176.6 GAN09857.1 - 0.01 15.8 0.1 2 8.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4838 PF16126.5 GAN09857.1 - 0.027 13.9 1.3 0.033 13.6 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) COMPASS-Shg1 PF05205.12 GAN09857.1 - 0.33 11.7 3.5 1.8 9.3 0.0 2.7 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 TPR_20 PF14561.6 GAN09857.1 - 0.55 10.6 3.7 1.8 9.0 0.0 3.2 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF4358 PF14270.6 GAN09857.1 - 0.98 9.8 7.2 0.2 12.0 0.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4358) TPR_14 PF13428.6 GAN09857.1 - 1 10.3 3.9 43 5.3 0.0 4.4 5 1 1 6 6 4 0 Tetratricopeptide repeat ENTH PF01417.20 GAN09858.1 - 7.9e-48 161.6 0.1 1.6e-47 160.7 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAN09858.1 - 6.6e-07 28.6 0.5 6.2e-06 25.4 0.5 2.3 1 1 0 1 1 1 1 ANTH domain Abhydrolase_3 PF07859.13 GAN09859.1 - 1.3e-24 87.2 0.0 2.2e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAN09859.1 - 1.3e-09 37.4 0.0 4.6e-07 29.0 0.0 2.0 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAN09859.1 - 0.0087 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family STIMATE PF12400.8 GAN09860.1 - 3.5e-40 137.4 11.4 5.1e-40 136.9 11.4 1.2 1 0 0 1 1 1 1 STIMATE family Zip PF02535.22 GAN09860.1 - 0.051 12.8 1.4 0.11 11.7 1.4 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter DEAD PF00270.29 GAN09861.1 - 1.3e-41 142.3 0.0 2.8e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN09861.1 - 7.7e-23 81.0 0.6 5.8e-22 78.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN09861.1 - 1.9e-09 37.8 4.9 4.9e-09 36.4 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAN09861.1 - 0.0053 17.0 0.0 0.52 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 GAN09861.1 - 0.088 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain UPF0565 PF10561.9 GAN09861.1 - 3.2 6.9 0.0 3.2 6.9 0.0 2.9 3 1 0 3 3 3 0 Uncharacterised protein family UPF0565 Suf PF05843.14 GAN09861.1 - 3.6 7.5 14.8 7.2 6.5 14.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Na_Ca_ex PF01699.24 GAN09862.1 - 2.9e-21 76.0 25.9 5.5e-16 58.9 9.9 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 GAN09862.1 - 1.7e-15 57.5 9.8 1.7e-15 57.5 9.8 4.2 3 0 0 3 3 3 1 Inner membrane component domain Casein_kappa PF00997.18 GAN09862.1 - 0.024 14.8 2.6 0.045 13.9 2.6 1.4 1 0 0 1 1 1 0 Kappa casein MFS_1 PF07690.16 GAN09863.1 - 3.5e-23 82.1 31.7 2e-22 79.6 31.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN09863.1 - 2.7e-09 36.4 9.6 2.7e-09 36.4 9.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OMP_b-brl_2 PF13568.6 GAN09863.1 - 0.06 13.4 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF4099 PF13351.6 GAN09864.1 - 0.12 12.6 4.3 0.09 13.0 1.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4099) TRAP-gamma PF07074.12 GAN09864.1 - 0.27 10.8 3.1 0.73 9.4 3.1 1.7 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Cep57_CLD_2 PF14197.6 GAN09864.1 - 8 6.6 33.8 0.15 12.2 6.0 4.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Fungal_trans PF04082.18 GAN09865.1 - 2.9e-08 33.1 2.1 4.7e-08 32.4 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN09865.1 - 5e-08 32.9 8.2 1.1e-07 31.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 GAN09866.1 - 3.7e-11 42.7 0.0 5.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN09866.1 - 0.086 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 GAN09866.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated NUDIX PF00293.28 GAN09867.1 - 1.7e-18 66.9 0.0 2.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 GAN09867.1 - 0.0004 20.3 0.2 0.00076 19.4 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain RC-P840_PscD PF10657.9 GAN09867.1 - 0.074 13.2 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD SRP68 PF16969.5 GAN09868.1 - 9.1e-118 394.7 23.9 9.9e-117 391.2 23.9 1.9 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 zf-RING_2 PF13639.6 GAN09868.1 - 6.6e-07 29.6 2.1 6.6e-07 29.6 2.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN09868.1 - 5.1e-05 23.0 1.7 5.1e-05 23.0 1.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN09868.1 - 6.2e-05 23.2 6.1 0.00013 22.2 6.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAN09868.1 - 0.00012 21.9 3.2 0.00027 20.8 3.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAN09868.1 - 0.00017 21.4 4.4 0.00046 20.0 4.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAN09868.1 - 0.0013 18.8 1.9 0.0029 17.6 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 GAN09868.1 - 0.0054 16.4 1.7 0.0054 16.4 1.7 2.1 2 0 0 2 2 1 1 RING-like zinc finger TPR_6 PF13174.6 GAN09868.1 - 0.043 14.5 0.6 1.3 9.8 0.5 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Nse PF11789.8 GAN09868.1 - 0.046 13.5 1.8 0.093 12.6 1.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GAN09868.1 - 0.1 12.7 4.8 0.47 10.5 4.6 2.3 1 1 0 1 1 1 0 RING-type zinc-finger TPR_12 PF13424.6 GAN09868.1 - 0.12 12.7 4.0 0.35 11.2 0.5 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-C3H2C3 PF17122.5 GAN09868.1 - 0.15 12.2 3.8 0.47 10.5 3.8 1.9 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 GAN09868.1 - 0.18 12.0 3.9 2 8.7 3.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAN09868.1 - 0.22 11.2 8.6 0.021 14.5 2.0 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 GAN09868.1 - 0.92 9.4 4.5 0.24 11.3 1.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN09868.1 - 2.6 8.0 6.1 0.22 11.4 1.3 1.6 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 RPN6_N PF18055.1 GAN09868.1 - 3.4 8.0 7.8 9.9 6.5 0.8 3.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_10 PF13374.6 GAN09868.1 - 5.2 7.1 7.1 1.1 9.2 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Arf PF00025.21 GAN09869.1 - 1.7e-66 223.0 0.0 1.9e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAN09869.1 - 2.8e-10 39.9 0.0 3.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAN09869.1 - 4.5e-10 39.2 0.0 1.8e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAN09869.1 - 2.2e-08 34.3 0.0 5.3e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN09869.1 - 1.2e-07 31.5 0.0 1.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAN09869.1 - 4e-07 30.1 0.0 6.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN09869.1 - 5.8e-06 25.8 0.0 6.6e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 GAN09869.1 - 0.045 13.5 0.0 0.3 10.8 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arrestin_N PF00339.29 GAN09870.1 - 2.5e-08 34.1 0.1 1.1e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 GAN09870.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Rgp1 Pkinase PF00069.25 GAN09871.1 - 4e-71 239.5 0.0 5.9e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN09871.1 - 2.9e-35 121.8 0.0 4.6e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN09871.1 - 1.9e-05 24.1 0.0 3.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like MAPEG PF01124.18 GAN09872.1 - 7e-06 26.0 2.3 8.7e-06 25.7 2.3 1.1 1 0 0 1 1 1 1 MAPEG family FixP_N PF14715.6 GAN09872.1 - 0.1 12.4 0.8 0.1 12.4 0.8 2.9 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Methyltransf_28 PF02636.17 GAN09877.1 - 1.1e-45 156.3 0.0 1.6e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_28 PF02636.17 GAN09878.1 - 3.7e-18 66.1 0.0 4.6e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase OPT PF03169.15 GAN09879.1 - 3.1e-156 521.6 44.3 3.5e-156 521.4 44.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BCS1_N PF08740.11 GAN09880.1 - 1.5e-17 64.2 0.2 2.8e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAN09880.1 - 5.7e-17 62.4 0.0 1.3e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAN09880.1 - 0.00019 21.8 0.0 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 GAN09880.1 - 0.00022 21.1 0.2 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAN09880.1 - 0.00028 20.9 0.0 0.0019 18.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAN09880.1 - 0.001 18.8 0.2 0.0041 16.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 GAN09880.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAN09880.1 - 0.0022 17.7 0.0 0.034 13.9 0.0 2.6 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAN09880.1 - 0.0047 17.5 0.0 0.021 15.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAN09880.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAN09880.1 - 0.0074 16.7 0.1 0.035 14.5 0.0 2.3 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 GAN09880.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAN09880.1 - 0.0095 15.3 0.0 0.037 13.4 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_6 PF12774.7 GAN09880.1 - 0.011 14.7 0.0 0.03 13.3 0.0 1.7 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 GAN09880.1 - 0.017 15.4 0.0 0.14 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 GAN09880.1 - 0.023 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 GAN09880.1 - 0.041 13.7 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 GAN09880.1 - 0.063 13.2 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 GAN09880.1 - 0.075 13.2 0.2 0.48 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 GAN09880.1 - 0.11 12.8 0.3 0.33 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 GAN09880.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain B56 PF01603.20 GAN09881.1 - 1.2e-173 577.9 8.3 1.5e-173 577.6 8.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 GAN09881.1 - 0.043 13.7 1.3 1.4 8.8 0.3 2.6 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UDPGT PF00201.18 GAN09882.1 - 1.6e-25 89.9 0.1 3.9e-25 88.6 0.1 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN09882.1 - 5.4e-06 26.5 0.0 9.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Integrase_H2C2 PF17921.1 GAN09884.1 - 7.2e-08 32.4 1.5 1.5e-07 31.4 0.3 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain HNH_2 PF13391.6 GAN09884.1 - 0.05 13.7 0.6 0.3 11.3 0.2 2.5 2 0 0 2 2 2 0 HNH endonuclease zf-H2C2 PF09337.10 GAN09884.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Amino_oxidase PF01593.24 GAN09886.1 - 3.3e-53 181.6 0.1 6e-53 180.7 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAN09886.1 - 2.6e-08 34.0 0.0 7.2e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAN09886.1 - 0.011 15.0 0.0 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAN09887.1 - 1.1e-79 268.5 1.0 1.3e-79 268.3 1.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAN09887.1 - 9.7e-14 51.7 0.8 1e-08 35.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAN09887.1 - 1.3e-08 34.6 5.0 6.2e-08 32.4 4.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN09887.1 - 5.3e-08 33.0 0.5 1.2e-06 28.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAN09887.1 - 1.8e-07 30.2 3.9 1.4e-05 24.0 0.3 3.2 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAN09887.1 - 1e-06 28.2 5.3 6.4e-06 25.6 3.4 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAN09887.1 - 1.4e-06 27.7 7.7 0.00043 19.5 0.4 3.5 4 0 0 4 4 4 3 Glucose inhibited division protein A Thi4 PF01946.17 GAN09887.1 - 1.3e-05 24.5 0.7 0.00052 19.3 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.6 GAN09887.1 - 0.0022 17.3 2.6 0.014 14.7 0.8 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAN09887.1 - 0.0034 16.7 0.2 0.0081 15.5 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 GAN09887.1 - 0.0044 17.0 0.7 2.2 8.3 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAN09887.1 - 0.0055 17.2 3.0 0.023 15.2 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 GAN09887.1 - 0.0093 15.4 0.4 0.82 9.0 0.1 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 GAN09887.1 - 0.013 14.8 0.4 0.022 14.0 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 GAN09887.1 - 0.014 14.8 0.4 2.6 7.2 0.2 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 GAN09887.1 - 0.052 12.4 0.4 0.08 11.8 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 GAN09887.1 - 0.097 11.7 1.6 0.094 11.7 0.3 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein MCRA PF06100.11 GAN09887.1 - 0.15 10.9 1.6 7.1 5.3 0.1 2.1 2 0 0 2 2 2 0 MCRA family 3HCDH_N PF02737.18 GAN09888.1 - 6.5e-61 205.4 3.3 2e-60 203.8 3.5 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAN09888.1 - 3.6e-32 110.9 0.2 1.1e-31 109.3 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAN09888.1 - 2.8e-06 27.6 3.6 7.7e-05 22.9 3.6 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 GAN09888.1 - 2.7e-05 23.6 2.3 5.8e-05 22.5 2.1 1.6 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 GAN09888.1 - 0.00017 20.9 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 GAN09888.1 - 0.00096 19.2 1.0 0.002 18.2 1.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 GAN09888.1 - 0.002 17.6 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAN09888.1 - 0.014 15.7 2.3 0.027 14.7 1.2 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 GAN09888.1 - 0.015 15.7 0.6 0.028 14.8 0.6 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 GAN09888.1 - 0.029 14.9 0.1 0.05 14.1 0.1 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.16 GAN09888.1 - 0.058 13.0 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 GAN09888.1 - 0.065 13.8 0.5 0.14 12.7 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 GAN09888.1 - 0.069 13.9 0.2 0.19 12.5 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 GAN09888.1 - 0.16 12.7 1.7 0.63 10.7 0.5 2.3 1 1 1 2 2 2 0 PglD N-terminal domain NAD_binding_8 PF13450.6 GAN09888.1 - 0.17 12.2 0.2 0.34 11.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 GAN09888.1 - 0.39 11.3 3.3 2.5 8.8 3.3 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAN09888.1 - 1.5 8.9 6.1 2.9 8.0 0.8 2.9 1 1 2 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF89 PF01937.19 GAN09889.1 - 9.7e-113 376.7 0.8 1.1e-112 376.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 HCV_NS1 PF01560.17 GAN09889.1 - 0.08 11.6 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 Hira PF07569.11 GAN09889.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split IF3_C PF00707.22 GAN09891.1 - 1.8e-13 50.2 1.7 2e-13 50.1 0.6 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 GAN09891.1 - 7.4e-10 39.0 0.1 1.8e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 GAN09891.1 - 0.0014 18.4 6.5 0.0027 17.4 6.0 1.8 2 0 0 2 2 2 1 Mitochondrial translation initiation factor SPC25 PF06703.11 GAN09891.1 - 0.6 9.9 3.3 22 4.8 1.4 2.7 1 1 2 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UDPGP PF01704.18 GAN09892.1 - 2.6e-56 191.0 0.0 3.3e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ABC2_membrane PF01061.24 GAN09893.1 - 5.4e-31 107.7 19.6 9.5e-31 106.9 19.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAN09893.1 - 4.2e-27 95.3 0.0 8.9e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAN09893.1 - 1.2e-05 25.3 0.0 0.049 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAN09893.1 - 0.00037 20.9 0.0 0.0009 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAN09893.1 - 0.0024 17.6 0.7 0.009 15.7 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAN09893.1 - 0.0044 16.9 0.2 0.01 15.8 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 GAN09893.1 - 0.0078 15.7 0.0 0.033 13.6 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAN09893.1 - 0.014 15.7 0.0 0.054 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAN09893.1 - 0.015 15.8 0.1 0.044 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAN09893.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 GAN09893.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 GAN09893.1 - 0.022 14.4 0.4 1.7 8.2 0.1 2.9 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 GAN09893.1 - 0.065 13.5 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAN09893.1 - 0.087 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAN09893.1 - 0.12 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAN09893.1 - 0.16 12.4 0.1 0.78 10.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 GAN09893.1 - 1.1 8.2 23.1 3.4 6.7 23.1 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DAGAT PF03982.13 GAN09894.1 - 7.2e-96 320.6 0.0 8.9e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Polysacc_deac_1 PF01522.21 GAN09895.1 - 9.9e-07 28.7 0.3 6.7e-06 26.0 0.3 2.3 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF4538 PF15061.6 GAN09896.1 - 0.38 10.5 1.3 0.91 9.3 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) ATP11 PF06644.11 GAN09897.1 - 1.6e-56 192.1 3.2 3.6e-36 125.4 0.1 2.1 2 0 0 2 2 2 2 ATP11 protein HDA2-3 PF11496.8 GAN09897.1 - 0.1 11.8 0.7 0.23 10.6 0.6 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 RPA43_OB PF17875.1 GAN09898.1 - 5.6e-26 91.6 0.2 1.9e-25 89.9 0.1 1.8 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 GAN09898.1 - 4.6e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 LysM PF01476.20 GAN09899.1 - 3.5e-06 27.0 0.0 5.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 LysM domain PAT1 PF09770.9 GAN09899.1 - 6.7 4.9 25.5 7.5 4.7 25.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ParA PF10609.9 GAN09900.1 - 4e-100 334.3 0.0 4.7e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAN09900.1 - 2.3e-09 37.4 0.0 4.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAN09900.1 - 2.9e-08 33.8 1.6 4.5e-07 29.9 1.6 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 GAN09900.1 - 5.9e-07 29.0 0.0 1.5e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 GAN09900.1 - 4.9e-05 22.4 0.4 6.9e-05 21.9 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 GAN09900.1 - 8.4e-05 21.9 1.8 0.00022 20.5 1.3 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 GAN09900.1 - 0.00016 21.3 0.1 0.00053 19.5 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 GAN09900.1 - 0.0071 15.8 0.2 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 GAN09900.1 - 0.0083 15.7 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 GAN09900.1 - 0.0085 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CLP1_P PF16575.5 GAN09900.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_26 PF13500.6 GAN09900.1 - 0.023 14.5 0.1 3.7 7.3 0.5 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAN09900.1 - 0.067 12.8 0.1 0.3 10.7 0.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 GAN09900.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 GAN09900.1 - 0.27 11.0 0.2 0.48 10.1 0.2 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 GAN09900.1 - 0.35 10.8 1.9 0.68 9.8 1.9 1.4 1 0 0 1 1 1 0 RsgA GTPase Dus PF01207.17 GAN09901.1 - 2e-72 243.9 0.0 2.4e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 GAN09901.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 GAN09901.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 GAN09901.1 - 0.022 14.0 0.0 4.3 6.5 0.0 2.1 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.20 GAN09901.1 - 0.041 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family TGT PF01702.18 GAN09902.1 - 2.3e-148 494.1 0.0 2.6e-148 493.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TMEM132D_C PF15706.5 GAN09903.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term VMA21 PF09446.10 GAN09904.1 - 3.1e-13 49.6 9.0 4.3e-13 49.2 9.0 1.2 1 0 0 1 1 1 1 VMA21-like domain Pro_isomerase PF00160.21 GAN09905.1 - 4.1e-47 160.4 0.1 4.1e-47 160.4 0.1 2.0 2 1 0 2 2 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PPP4R2 PF09184.11 GAN09905.1 - 0.036 13.7 15.7 0.047 13.3 15.7 1.1 1 0 0 1 1 1 0 PPP4R2 SLC12 PF03522.15 GAN09905.1 - 0.042 12.9 13.8 0.057 12.4 13.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 GAN09905.1 - 0.19 11.8 6.4 0.29 11.2 6.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SelP_N PF04592.14 GAN09905.1 - 0.63 9.4 18.2 1 8.7 18.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Menin PF05053.13 GAN09905.1 - 1.1 7.5 9.7 1.5 7.1 9.7 1.2 1 0 0 1 1 1 0 Menin LAP1C PF05609.12 GAN09905.1 - 1.9 7.5 18.5 2.4 7.2 18.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 GAN09905.1 - 2 6.8 15.2 2.5 6.6 15.2 1.1 1 0 0 1 1 1 0 Macoilin family Pneumo_att_G PF05539.11 GAN09905.1 - 4.3 6.8 12.7 6.3 6.3 12.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G AF-4 PF05110.13 GAN09905.1 - 4.9 5.1 30.6 6.4 4.7 30.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Hid1 PF12722.7 GAN09905.1 - 6.9 4.7 18.2 8.3 4.4 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPRTase PF14681.6 GAN09906.1 - 4.1e-65 219.1 0.0 6.1e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 GAN09906.1 - 1e-62 211.4 0.1 1.4e-62 210.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 GAN09906.1 - 1.3e-05 25.1 0.0 3.1e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CoaE PF01121.20 GAN09906.1 - 0.00073 19.3 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_18 PF13238.6 GAN09906.1 - 0.0013 19.3 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN09906.1 - 0.0043 17.2 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAN09906.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF981 PF06168.11 GAN09906.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF4257 PF14074.6 GAN09906.1 - 0.17 12.1 0.3 0.36 11.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) AAA_17 PF13207.6 GAN09906.1 - 0.19 12.2 0.1 12 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Podoplanin PF05808.11 GAN09907.1 - 0.36 10.9 0.1 0.36 10.9 0.1 7.9 3 1 3 6 6 6 0 Podoplanin RRM_1 PF00076.22 GAN09908.1 - 1.7e-32 111.0 0.2 6.1e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN09908.1 - 4.5e-07 29.9 0.4 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 GAN09908.1 - 7.3e-06 26.0 2.2 0.0017 18.4 0.1 2.6 1 1 1 2 2 2 2 Limkain b1 RRM_5 PF13893.6 GAN09908.1 - 4.1e-05 23.2 0.0 0.21 11.2 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN09908.1 - 0.034 14.2 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 GAN09908.1 - 0.046 13.4 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated MatE PF01554.18 GAN09909.1 - 2.6e-44 150.7 40.7 4.9e-28 97.8 12.9 3.0 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 GAN09909.1 - 0.00095 19.2 7.5 0.00095 19.2 7.5 5.5 4 2 1 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Abhydrolase_9_N PF15420.6 GAN09909.1 - 0.043 13.8 8.2 0.63 10.0 0.1 2.8 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus MOZ_SAS PF01853.18 GAN09910.1 - 1.4e-83 278.9 5.1 1e-82 276.1 0.4 2.9 3 0 0 3 3 3 2 MOZ/SAS family zf-MYST PF17772.1 GAN09910.1 - 3.5e-21 74.6 3.9 3.5e-21 74.6 3.9 2.5 3 0 0 3 3 3 1 MYST family zinc finger domain PHD PF00628.29 GAN09910.1 - 1.1e-10 41.3 12.9 1.1e-10 41.3 12.9 4.1 2 1 1 3 3 3 1 PHD-finger FAD_binding_6 PF00970.24 GAN09911.1 - 5.6e-31 106.8 0.0 9e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAN09911.1 - 7e-30 103.9 0.0 9.9e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAN09911.1 - 8.8e-07 29.2 0.0 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TPR_1 PF00515.28 GAN09913.1 - 1.5e-17 62.5 1.4 0.00019 21.1 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAN09913.1 - 3.3e-10 39.5 4.7 0.0069 16.1 0.0 5.8 4 2 2 6 6 5 3 TPR repeat TPR_2 PF07719.17 GAN09913.1 - 3.7e-10 39.1 3.3 0.00035 20.4 0.2 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAN09913.1 - 2.2e-09 37.7 6.9 0.00012 22.5 1.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN09913.1 - 6.1e-08 32.3 1.8 0.033 14.4 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN09913.1 - 3.7e-07 30.7 2.8 0.022 15.4 0.1 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAN09913.1 - 5.7e-07 29.5 1.6 0.014 15.7 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN09913.1 - 7.7e-06 26.3 13.6 2 9.4 1.7 6.9 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_20 PF14561.6 GAN09913.1 - 9.9e-06 25.8 7.0 0.002 18.5 0.2 3.9 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAN09913.1 - 1.1e-05 25.7 9.3 0.017 15.4 2.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN09913.1 - 1.7e-05 24.9 6.1 0.094 12.9 0.5 3.9 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAN09913.1 - 0.00019 21.2 2.4 0.64 10.2 0.7 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN09913.1 - 0.019 15.6 0.7 7.7 7.4 0.1 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAN09913.1 - 0.023 14.6 5.2 0.037 13.9 2.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RAM PF15320.6 GAN09913.1 - 0.031 14.9 0.8 0.095 13.3 0.8 1.8 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein DUF4248 PF14053.6 GAN09913.1 - 0.076 13.1 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) ANAPC3 PF12895.7 GAN09913.1 - 0.34 11.2 3.3 1 9.6 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sugar_tr PF00083.24 GAN09914.1 - 6.6e-48 163.7 20.5 1.2e-27 96.9 5.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN09914.1 - 1.1e-16 60.7 37.3 1.1e-09 37.8 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRAPPC9-Trs120 PF08626.11 GAN09915.1 - 0 1099.9 1.1 0 1099.7 1.1 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 GAN09915.1 - 0.00043 20.5 0.7 0.00088 19.5 0.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN09915.1 - 0.11 12.6 0.2 0.28 11.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAN09915.1 - 0.18 11.7 0.1 0.45 10.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cation_efflux PF01545.21 GAN09916.1 - 1e-28 100.4 12.3 1.4e-28 100.0 12.3 1.2 1 0 0 1 1 1 1 Cation efflux family WD40 PF00400.32 GAN09916.1 - 3.4e-22 78.3 9.5 7.2e-07 29.8 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ZT_dimer PF16916.5 GAN09916.1 - 1.1e-08 35.1 0.1 5.3e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter ANAPC4_WD40 PF12894.7 GAN09916.1 - 1.2e-08 35.1 0.3 0.001 19.3 0.1 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN09916.1 - 0.00027 19.7 1.1 0.25 9.9 0.3 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 LisH PF08513.11 GAN09916.1 - 0.00063 19.6 0.3 0.0012 18.8 0.3 1.5 1 0 0 1 1 1 1 LisH PD40 PF07676.12 GAN09916.1 - 0.83 9.7 3.6 28 4.8 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4134 PF13572.6 GAN09917.1 - 1.7 9.0 8.2 6.7 7.1 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4134) ADH_N PF08240.12 GAN09919.1 - 2e-17 63.0 12.0 4.7e-17 61.9 12.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN09919.1 - 7.6e-12 45.3 0.0 1.2e-09 38.3 0.1 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN09919.1 - 0.00012 23.1 0.0 0.00019 22.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAN09919.1 - 0.00022 20.7 0.1 0.00039 19.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 GAN09919.1 - 0.0046 16.7 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 GAN09919.1 - 0.04 13.2 0.1 0.059 12.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NADH_4Fe-4S PF10589.9 GAN09919.1 - 0.047 13.8 1.6 0.13 12.4 0.5 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Fungal_trans PF04082.18 GAN09920.1 - 1.8e-18 66.6 4.2 1.8e-18 66.6 4.2 3.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN09920.1 - 1.7e-10 40.9 6.0 2.9e-10 40.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_3 PF13812.6 GAN09921.1 - 0.003 17.6 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAN09921.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.5 2 0 0 2 2 2 0 PPR repeat family Nodulin-like PF06813.13 GAN09922.1 - 1.2e-10 41.3 4.7 1.2e-10 41.3 4.7 1.7 2 0 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 GAN09922.1 - 1.6e-10 40.5 31.7 1.6e-10 40.5 31.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Kelch_5 PF13854.6 GAN09925.1 - 1.7e-12 47.1 0.0 0.23 11.5 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAN09925.1 - 6.6e-08 32.6 0.2 0.44 10.9 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAN09925.1 - 5.2e-07 29.6 1.7 1.2 9.2 0.0 6.3 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAN09925.1 - 0.00058 19.4 0.2 3.8 7.2 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Herpes_gE PF02480.16 GAN09925.1 - 0.026 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RCC1_2 PF13540.6 GAN09925.1 - 0.073 12.9 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Lyase_8 PF02278.18 GAN09926.1 - 3.2e-65 220.2 6.6 4.9e-65 219.6 6.6 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 GAN09926.1 - 1e-24 87.1 0.2 1.7e-24 86.4 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 GAN09926.1 - 1.9e-13 50.7 0.5 4.7e-13 49.4 0.5 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Pox_VP8_L4R PF04498.12 GAN09926.1 - 0.011 15.3 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus nucleic acid binding protein VP8/L4R DUF2012 PF09430.10 GAN09926.1 - 0.023 14.8 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) LRR_8 PF13855.6 GAN09927.1 - 4.5e-33 112.8 22.3 3e-09 36.5 1.5 3.3 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAN09927.1 - 8e-12 45.2 5.3 0.00051 20.4 0.1 3.9 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN09927.1 - 1e-06 28.5 2.3 7.5 7.5 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 GAN09927.1 - 1.4e-05 24.8 2.4 3.7 7.8 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 GAN09927.1 - 1.4e-05 24.6 0.3 0.043 13.3 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Alba PF01918.21 GAN09928.1 - 1.5e-15 56.7 0.8 2.6e-15 56.0 0.8 1.4 1 0 0 1 1 1 1 Alba ALC PF17527.2 GAN09928.1 - 0.054 13.1 0.2 0.15 11.7 0.2 1.7 2 0 0 2 2 2 0 Phage ALC protein Rpp20 PF12328.8 GAN09928.1 - 0.11 12.4 2.5 0.15 12.0 2.5 1.3 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P CorA PF01544.18 GAN09929.1 - 0.16 11.3 5.7 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein S10_plectin PF03501.15 GAN09930.1 - 1.5e-43 146.8 0.1 1.8e-43 146.5 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Kinase-like PF14531.6 GAN09930.1 - 0.045 13.1 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like TrmB PF01978.19 GAN09930.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF1495 PF07381.11 GAN09930.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF2250 PF10007.9 GAN09930.1 - 0.39 10.9 1.0 20 5.4 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Ribosomal_L16 PF00252.18 GAN09931.1 - 2.6e-11 43.7 0.0 7.5e-10 38.9 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein L16p/L10e VWA_2 PF13519.6 GAN09932.1 - 6.1e-25 88.0 4.4 2.7e-24 85.9 0.1 3.5 2 2 2 4 4 4 1 von Willebrand factor type A domain Ssl1 PF04056.14 GAN09932.1 - 6.4e-09 35.9 0.7 7.7e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Ssl1-like UIM PF02809.20 GAN09932.1 - 1e-07 31.3 27.9 0.00085 19.1 1.3 5.5 5 0 0 5 5 5 3 Ubiquitin interaction motif Vps35 PF03635.17 GAN09933.1 - 0 1054.5 3.1 0 1054.3 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MFS_1 PF07690.16 GAN09934.1 - 1.6e-38 132.6 30.3 7.1e-38 130.4 31.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TcpE PF12648.7 GAN09934.1 - 0.08 13.5 0.5 0.08 13.5 0.5 3.1 2 1 1 3 3 3 0 TcpE family ARD PF03079.14 GAN09935.1 - 1.7e-52 177.8 0.2 1.9e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 GAN09935.1 - 5.9e-10 38.7 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GAN09935.1 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 GAN09935.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 GAN09935.1 - 0.047 13.3 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase EF-hand_1 PF00036.32 GAN09936.1 - 1.6e-42 139.9 9.2 5.6e-10 38.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN09936.1 - 2.6e-35 120.7 2.8 7.8e-19 67.9 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAN09936.1 - 2.2e-32 110.6 10.8 2.1e-14 53.1 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAN09936.1 - 6.8e-32 106.7 4.3 2.4e-09 36.4 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAN09936.1 - 7.8e-27 91.6 7.0 2.5e-06 26.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAN09936.1 - 1.1e-12 48.1 0.1 3e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAN09936.1 - 3.1e-10 40.4 0.4 0.00012 22.4 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAN09936.1 - 7.7e-09 35.5 0.9 0.0011 18.9 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 GAN09936.1 - 9.1e-06 25.7 1.6 6.6e-05 22.9 0.3 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 GAN09936.1 - 9.1e-06 26.5 0.0 0.0015 19.4 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 GAN09936.1 - 5.1e-05 23.3 0.5 0.98 9.3 0.0 3.8 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 GAN09936.1 - 5.8e-05 23.2 3.6 0.017 15.3 0.1 3.0 1 1 2 3 3 3 2 Dockerin type I domain TerB PF05099.13 GAN09936.1 - 0.00089 19.2 0.6 0.24 11.4 0.0 2.6 1 1 2 3 3 3 1 Tellurite resistance protein TerB DUF3349 PF11829.8 GAN09936.1 - 0.0029 18.4 0.2 3.9 8.3 0.1 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Fe_hyd_lg_C PF02906.14 GAN09936.1 - 0.003 17.3 0.5 0.0045 16.7 0.5 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain RNA_pol_Rpb4 PF03874.16 GAN09936.1 - 0.0045 17.3 2.9 0.62 10.4 0.2 3.1 2 1 1 3 3 3 1 RNA polymerase Rpb4 UPF0154 PF03672.13 GAN09936.1 - 0.0052 16.8 0.0 0.19 11.8 0.0 2.5 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 GAN09936.1 - 0.0071 14.9 0.0 0.0082 14.7 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 GAN09936.1 - 0.014 15.2 1.0 0.68 9.8 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain PY_rept_46 PF09689.10 GAN09936.1 - 0.015 15.9 1.0 7.1 7.3 0.0 3.0 2 1 1 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) DUF2267 PF10025.9 GAN09936.1 - 0.028 14.7 0.0 0.078 13.3 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF1811 PF08838.10 GAN09936.1 - 0.032 14.5 0.6 5 7.4 0.1 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1811) PhageMin_Tail PF10145.9 GAN09936.1 - 0.045 13.6 0.3 0.091 12.6 0.1 1.6 2 0 0 2 2 2 0 Phage-related minor tail protein Poly_export PF02563.16 GAN09936.1 - 0.054 13.7 0.0 6.9 7.0 0.0 2.8 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein DUF853 PF05872.12 GAN09936.1 - 0.072 11.7 0.1 0.21 10.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) MotA_activ PF09114.10 GAN09936.1 - 0.079 13.1 0.0 0.98 9.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain XkdW PF09636.10 GAN09936.1 - 0.088 12.9 0.1 0.71 10.0 0.0 2.2 1 1 1 2 2 2 0 XkdW protein Peptidase_M24 PF00557.24 GAN09936.1 - 0.1 12.3 0.2 0.98 9.1 0.1 2.1 1 1 0 2 2 2 0 Metallopeptidase family M24 EF-hand_14 PF17959.1 GAN09936.1 - 0.11 12.8 0.1 13 6.3 0.0 2.5 1 1 0 2 2 2 0 EF-hand domain DUF4497 PF14924.6 GAN09936.1 - 0.11 12.9 0.0 1.6 9.2 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4497) Deltameth_res PF16020.5 GAN09937.1 - 0.54 10.2 0.2 0.54 10.2 0.2 2.3 3 0 0 3 3 3 0 Deltamethrin resistance IF-2B PF01008.17 GAN09938.1 - 5.6e-62 209.5 0.2 3e-58 197.3 0.1 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family Pes-10 PF07149.11 GAN09938.1 - 0.043 12.9 2.6 0.073 12.1 2.6 1.3 1 0 0 1 1 1 0 Pes-10 Sporozoite_P67 PF05642.11 GAN09938.1 - 0.35 8.9 1.6 0.48 8.4 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GCIP PF13324.6 GAN09938.1 - 0.49 10.0 4.2 0.88 9.1 4.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DASH_Dam1 PF08653.10 GAN09939.1 - 3.8e-14 52.2 0.6 5.9e-14 51.6 0.0 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 DUF3597 PF12200.8 GAN09939.1 - 0.46 11.0 5.5 0.58 10.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) DUF4674 PF15719.5 GAN09939.1 - 4 7.4 7.6 7.7 6.5 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Smg4_UPF3 PF03467.15 GAN09940.1 - 1.9e-59 200.6 2.1 1.9e-59 200.6 2.1 3.7 4 1 0 4 4 4 1 Smg-4/UPF3 family APG6_N PF17675.1 GAN09940.1 - 7.2 7.1 13.3 16 6.0 13.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3540 PF12059.8 GAN09941.1 - 1.9 8.2 6.4 1.3 8.8 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) CHASE8 PF17152.4 GAN09941.1 - 3.5 7.9 6.4 1.2 9.5 2.5 2.1 2 0 0 2 2 2 0 Periplasmic sensor domain GoLoco PF02188.17 GAN09942.1 - 0.075 12.6 7.2 0.2 11.2 0.4 4.1 4 0 0 4 4 4 0 GoLoco motif RasGAP PF00616.19 GAN09943.1 - 1.3e-18 67.5 0.2 9.9e-12 45.0 0.0 3.2 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAN09943.1 - 3.4e-17 62.9 1.0 1.4e-16 60.9 1.0 2.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAN09943.1 - 2.1e-05 24.3 0.3 5.3e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain MOR2-PAG1_C PF14225.6 GAN09943.1 - 0.0001 22.2 0.8 0.00057 19.8 0.1 2.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal SPA PF08616.10 GAN09945.1 - 1.6e-11 44.2 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DUF3020 PF11223.8 GAN09946.1 - 1.2e-17 64.2 4.8 1.2e-17 64.2 4.8 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3020) Vezatin PF12632.7 GAN09947.1 - 8.1e-51 173.0 7.5 8.1e-51 173.0 7.5 2.0 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes SLATT_1 PF18181.1 GAN09947.1 - 0.063 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF16 PF01519.16 GAN09947.1 - 3.3 8.3 8.2 1.2 9.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Methyltrn_RNA_3 PF02598.17 GAN09948.1 - 9.6e-95 317.4 0.0 1.1e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Lin-8 PF03353.15 GAN09949.1 - 0.54 9.8 16.4 0.87 9.1 16.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SRP-alpha_N PF04086.13 GAN09949.1 - 1.2 9.0 21.9 1.8 8.4 21.9 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MMR_HSR1 PF01926.23 GAN09950.1 - 2.9e-22 78.9 0.0 4.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAN09950.1 - 2.9e-08 33.4 0.2 7.9e-08 32.0 0.0 1.7 1 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAN09950.1 - 4.4e-07 29.9 0.1 1.4e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 GAN09950.1 - 2.9e-06 26.8 1.4 0.01 15.1 1.4 2.9 1 1 0 1 1 1 1 Septin SRPRB PF09439.10 GAN09950.1 - 1e-05 25.1 0.1 2.2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 GAN09950.1 - 1.6e-05 25.1 0.2 0.051 13.6 0.2 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 GAN09950.1 - 0.00032 20.3 0.1 0.17 11.4 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 GAN09950.1 - 0.0041 16.4 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 2 NB-ARC domain TniB PF05621.11 GAN09950.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 GAN09950.1 - 0.029 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAN09950.1 - 0.035 13.4 0.1 0.066 12.5 0.1 1.4 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 GAN09950.1 - 0.046 14.2 0.0 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 GAN09950.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAN09950.1 - 0.06 13.3 0.3 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAN09950.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN09950.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain MBOAT PF03062.19 GAN09951.1 - 1.9e-48 165.6 31.5 3.7e-48 164.6 31.5 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family bZIP_2 PF07716.15 GAN09952.1 - 3.2e-10 39.9 6.3 3.2e-10 39.9 6.3 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN09952.1 - 6.3e-06 26.2 12.9 1.3e-05 25.2 9.9 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAN09952.1 - 0.01 16.3 5.7 0.016 15.7 5.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 GAN09952.1 - 0.014 15.2 3.2 0.023 14.4 3.2 1.3 1 0 0 1 1 1 0 Septum formation initiator KASH_CCD PF14662.6 GAN09952.1 - 0.018 14.9 3.4 0.025 14.4 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 GAN09952.1 - 0.022 13.9 2.1 0.032 13.5 2.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ZapB PF06005.12 GAN09952.1 - 0.27 11.7 7.3 0.21 12.1 5.6 1.6 1 1 1 2 2 2 0 Cell division protein ZapB Striatin PF08232.12 GAN09952.1 - 0.84 10.2 6.3 0.17 12.5 1.1 2.1 1 1 1 2 2 2 0 Striatin family WD40 PF00400.32 GAN09953.1 - 6.6e-27 93.2 10.1 7.2e-05 23.5 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN09953.1 - 1.7e-08 34.7 0.2 0.018 15.3 0.1 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN09953.1 - 0.00098 19.0 0.0 0.87 9.4 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAN09953.1 - 0.0049 16.2 0.0 2.6 7.3 0.0 2.5 1 1 1 3 3 3 2 WD40-like domain DUF2397 PF09660.10 GAN09953.1 - 0.11 11.4 1.6 0.15 10.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF1325 PF07039.11 GAN09954.1 - 1.6e-36 125.3 2.3 1.6e-36 125.3 2.3 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 GAN09954.1 - 5.1e-06 26.2 0.4 1.1e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 GAN09954.1 - 0.00024 21.1 1.2 0.31 11.1 0.5 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4537) DUF4819 PF16090.5 GAN09954.1 - 0.0013 18.8 0.2 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4819) LBR_tudor PF09465.10 GAN09954.1 - 0.0013 18.5 0.0 0.087 12.6 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Agenet PF05641.12 GAN09954.1 - 0.0025 18.2 1.7 3 8.4 0.0 2.9 3 0 0 3 3 3 2 Agenet domain CotH PF08757.11 GAN09955.1 - 6e-30 104.9 3.7 9.4e-30 104.2 3.7 1.3 1 0 0 1 1 1 1 CotH kinase protein Nup192 PF11894.8 GAN09956.1 - 1.2e-191 639.4 40.3 1.4e-191 639.1 40.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF1681 PF07933.14 GAN09956.1 - 7.2e-57 191.3 0.0 1.5e-56 190.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PhoLip_ATPase_C PF16212.5 GAN09957.1 - 1.6e-75 254.1 31.3 1.6e-75 254.1 31.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAN09957.1 - 4.6e-24 83.9 0.5 4.6e-24 83.9 0.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAN09957.1 - 1.1e-13 51.1 0.0 4.3e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAN09957.1 - 1.6e-11 44.9 0.8 0.0011 19.4 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAN09957.1 - 4.4e-07 29.6 0.0 4.4e-07 29.6 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAN09957.1 - 0.00064 19.5 0.4 0.009 15.8 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 GAN09957.1 - 1 9.5 7.3 1.6 8.9 5.6 2.2 2 0 0 2 2 2 0 C-terminus of AA_permease Chorion_2 PF03964.15 GAN09957.1 - 2.7 8.9 8.9 11 6.9 2.5 2.6 2 0 0 2 2 2 0 Chorion family 2 MFS_1 PF07690.16 GAN09958.1 - 6.4e-28 97.7 46.9 6.4e-28 97.7 46.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAN09958.1 - 0.0006 18.8 4.8 0.0006 18.8 4.8 2.5 1 1 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 GAN09958.1 - 0.0022 16.9 17.8 0.0022 16.9 17.8 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter Cullin PF00888.22 GAN09959.1 - 1e-11 44.2 0.5 7.7e-11 41.3 0.0 2.1 1 1 1 2 2 2 1 Cullin family AidB_N PF18158.1 GAN09959.1 - 0.051 13.5 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Adaptive response protein AidB N-terminal domain Chitin_synth_2 PF03142.15 GAN09960.1 - 3.1e-279 927.0 0.7 4.2e-279 926.5 0.7 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAN09960.1 - 3e-13 50.2 0.0 2.9e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN09960.1 - 1.8e-11 44.3 3.1 5.1e-11 42.9 3.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAN09960.1 - 7.5e-05 22.6 0.0 0.0052 16.6 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAN09960.1 - 0.0094 15.4 0.0 0.052 13.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 VIR_N PF15912.5 GAN09960.1 - 0.16 11.5 8.5 0.38 10.3 8.5 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal BAR PF03114.18 GAN09961.1 - 2.1e-28 99.6 4.3 3.8e-28 98.7 4.3 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAN09961.1 - 2e-14 52.9 0.1 3.5e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN09961.1 - 3.3e-11 42.9 0.1 6e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN09961.1 - 1.4e-10 40.7 0.0 2.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF489 PF04356.12 GAN09961.1 - 0.084 12.9 2.2 4.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF489) FAM76 PF16046.5 GAN09961.1 - 1.6 8.0 6.1 0.15 11.4 0.7 1.9 2 0 0 2 2 2 0 FAM76 protein Orf78 PF06024.12 GAN09962.1 - 0.013 15.8 0.4 0.35 11.2 0.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 GAN09962.1 - 0.034 14.1 0.1 0.034 14.1 0.1 2.7 3 0 0 3 3 3 0 TMEM154 protein family EphA2_TM PF14575.6 GAN09962.1 - 0.082 13.8 0.0 0.36 11.7 0.0 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3619 PF12279.8 GAN09962.1 - 0.097 13.0 0.0 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) WD40 PF00400.32 GAN09964.1 - 0.00023 21.9 0.2 3.1 8.8 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Frtz PF11768.8 GAN09964.1 - 0.067 11.5 0.0 0.14 10.4 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz KH_1 PF00013.29 GAN09965.1 - 4e-44 148.3 6.0 4.7e-17 61.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAN09965.1 - 4.5e-10 39.2 7.1 0.012 15.4 0.1 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 GAN09965.1 - 9.3e-09 35.1 3.3 0.052 13.4 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAN09965.1 - 0.00069 19.7 7.0 0.18 11.9 0.1 3.7 4 0 0 4 4 4 2 NusA-like KH domain DGF-1_C PF11040.8 GAN09965.1 - 0.44 10.6 3.4 0.5 10.4 0.4 2.3 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus LIM PF00412.22 GAN09966.1 - 4.5e-20 71.6 93.0 1.2e-07 31.8 9.3 6.7 6 2 0 6 6 6 5 LIM domain Ank_2 PF12796.7 GAN09967.1 - 3.5e-18 66.0 0.4 5e-16 59.1 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN09967.1 - 3e-17 62.4 0.0 3.8e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN09967.1 - 4e-17 62.3 0.1 1.5e-11 44.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN09967.1 - 6e-13 47.7 0.0 5.5e-06 26.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAN09967.1 - 3.3e-12 46.3 0.0 1.3e-05 25.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat CAP_GLY PF01302.25 GAN09968.1 - 2.7e-22 78.6 0.2 2.7e-22 78.6 0.2 1.6 2 0 0 2 2 2 1 CAP-Gly domain BTB PF00651.31 GAN09968.1 - 8.9e-09 35.6 0.8 1.8e-08 34.6 0.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain PBP1_TM PF14812.6 GAN09968.1 - 0.58 10.6 5.0 1.2 9.5 5.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vac7 PF12751.7 GAN09969.1 - 2.4e-13 50.3 9.9 9.7e-13 48.3 9.4 2.1 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 Olduvai PF06758.13 GAN09969.1 - 0.68 10.2 3.2 3.9 7.8 3.2 2.4 1 1 0 1 1 1 0 Olduvai domain Septin PF00735.18 GAN09970.1 - 4.6e-91 305.0 4.0 2.5e-53 181.2 0.3 2.5 1 1 1 2 2 2 2 Septin Pyridox_oxase_2 PF12766.7 GAN09970.1 - 5.1e-25 88.0 1.3 2e-24 86.1 0.1 2.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GAN09970.1 - 2.5e-09 37.2 0.0 5.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GTP_EFTU PF00009.27 GAN09970.1 - 3.7e-09 36.4 2.8 3.4e-08 33.3 2.7 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN09970.1 - 9.8e-06 25.6 0.5 0.00051 20.0 0.2 2.8 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAN09970.1 - 6.8e-05 22.9 0.1 0.00026 21.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAN09970.1 - 0.0014 18.9 0.6 0.01 16.1 0.0 2.7 3 1 0 3 3 3 1 AAA domain Pox_A32 PF04665.12 GAN09970.1 - 0.0018 17.8 1.0 0.017 14.6 0.2 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Roc PF08477.13 GAN09970.1 - 0.0037 17.5 0.1 0.017 15.4 0.1 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN09970.1 - 0.012 15.2 0.1 0.036 13.6 0.1 1.8 1 0 0 1 1 1 0 Ras family Sigma54_activat PF00158.26 GAN09970.1 - 0.024 14.4 0.3 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 GAN09970.1 - 0.024 15.0 0.2 0.18 12.2 0.0 2.7 3 0 0 3 3 2 0 RNA helicase Pyrid_ox_like PF16242.5 GAN09970.1 - 0.026 14.1 0.1 0.072 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Gtr1_RagA PF04670.12 GAN09970.1 - 0.041 13.2 2.3 0.075 12.4 0.4 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region GAPES3 PF17154.4 GAN09970.1 - 0.1 12.6 0.2 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain PduV-EutP PF10662.9 GAN09970.1 - 0.11 12.2 0.4 1.7 8.4 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GAN09970.1 - 0.13 12.6 0.0 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF29 PF01724.16 GAN09970.1 - 0.25 11.6 7.3 0.042 14.1 2.0 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF29 Kinesin PF00225.23 GAN09971.1 - 1.6e-95 319.9 0.0 2.2e-95 319.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAN09971.1 - 6.2e-18 65.2 0.1 1.4e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding DAHP_synth_1 PF00793.20 GAN09972.1 - 6.6e-102 340.1 0.1 8.1e-102 339.8 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family p450 PF00067.22 GAN09973.1 - 3.8e-68 230.3 0.0 4.8e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Clat_adaptor_s PF01217.20 GAN09974.1 - 3.9e-57 192.2 2.7 4.3e-57 192.0 2.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 GAN09974.1 - 0.0086 15.7 0.1 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain WD40 PF00400.32 GAN09975.1 - 2.7e-58 192.6 12.1 9.3e-09 35.8 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 GAN09975.1 - 6.2e-27 93.7 16.1 8.9e-27 93.2 16.1 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 GAN09975.1 - 5.8e-20 71.4 0.0 0.0072 16.6 0.0 6.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN09975.1 - 2.7e-07 30.2 0.0 0.011 15.1 0.0 4.2 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 GAN09975.1 - 4.9e-07 29.0 0.1 0.29 10.0 0.0 4.5 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CEP63 PF17045.5 GAN09975.1 - 0.00015 21.8 5.5 0.00024 21.1 5.5 1.3 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa PD40 PF07676.12 GAN09975.1 - 0.0007 19.5 0.2 0.79 9.7 0.0 4.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 GAN09975.1 - 0.013 14.8 0.1 6.2 6.1 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 GAN09975.1 - 0.02 13.6 0.0 0.42 9.3 0.0 2.7 2 1 0 2 2 2 0 Nup133 N terminal like Spc7 PF08317.11 GAN09975.1 - 0.025 13.5 10.8 0.037 12.9 10.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 GAN09975.1 - 0.062 13.6 3.9 0.11 12.8 3.9 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF724 PF05266.14 GAN09975.1 - 0.15 11.9 7.0 0.23 11.3 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nup160 PF11715.8 GAN09975.1 - 0.19 10.3 6.4 5.9 5.4 0.0 4.6 2 1 4 6 6 6 0 Nucleoporin Nup120/160 F_actin_bind PF08919.10 GAN09975.1 - 0.2 11.7 3.5 0.34 11.0 3.5 1.3 1 0 0 1 1 1 0 F-actin binding DUF3450 PF11932.8 GAN09975.1 - 0.55 9.5 13.3 0.93 8.8 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 GAN09975.1 - 0.55 9.6 12.2 0.79 9.1 12.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPX2 PF06886.11 GAN09975.1 - 1.2 9.4 5.4 2.2 8.6 5.4 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Jnk-SapK_ap_N PF09744.9 GAN09975.1 - 1.4 9.1 13.5 2.2 8.5 13.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 SKA2 PF16740.5 GAN09975.1 - 1.6 8.6 13.3 0.34 10.7 3.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 GAN09975.1 - 1.7 9.2 13.0 3 8.4 13.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region CREPT PF16566.5 GAN09975.1 - 2.6 8.2 9.5 4.3 7.5 9.5 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Chorismate_bind PF00425.18 GAN09976.1 - 3e-85 285.9 0.0 5.1e-85 285.1 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 GAN09976.1 - 1.5e-31 109.6 0.0 7.6e-21 74.7 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAN09976.1 - 2e-12 47.5 0.1 7e-09 36.0 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAN09976.1 - 7.5e-06 25.9 0.3 3.7e-05 23.6 0.3 2.1 1 1 0 1 1 1 1 Peptidase C26 PARM PF17061.5 GAN09977.1 - 1.3 9.1 17.5 2.3 8.3 17.5 1.5 1 0 0 1 1 1 0 PARM Vfa1 PF08432.10 GAN09978.1 - 6.9e-34 117.8 1.3 8.3e-34 117.5 1.3 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Zds_C PF08632.10 GAN09980.1 - 2.2e-25 88.1 0.6 2.2e-25 88.1 0.6 1.9 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term AAA PF00004.29 GAN09981.1 - 5.6e-91 301.9 0.0 1.1e-45 155.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN09981.1 - 2.7e-26 91.1 2.8 6.7e-14 51.4 0.6 2.5 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 GAN09981.1 - 5.1e-15 55.6 0.0 1.7e-07 31.1 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain O-FucT PF10250.9 GAN09981.1 - 5.8e-13 49.2 0.8 1.4e-11 44.7 0.8 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AAA_16 PF13191.6 GAN09981.1 - 9e-12 45.7 0.1 1.1e-06 29.2 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAN09981.1 - 2.4e-11 44.1 0.9 8.1e-05 22.9 0.1 5.2 3 2 2 5 5 5 2 AAA domain AAA_5 PF07728.14 GAN09981.1 - 4.5e-11 42.9 0.1 4.1e-05 23.6 0.1 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAN09981.1 - 3.4e-10 40.3 0.0 0.00015 21.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GAN09981.1 - 2e-09 37.1 0.0 0.0016 17.7 0.0 2.8 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 GAN09981.1 - 2.7e-08 34.1 0.0 0.00011 22.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAN09981.1 - 9.4e-07 28.9 0.0 0.002 18.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GAN09981.1 - 1.6e-06 27.9 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 GAN09981.1 - 3.9e-06 26.9 0.1 0.8 9.7 0.0 4.5 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAN09981.1 - 7.3e-06 26.3 0.0 0.28 11.6 0.0 3.3 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.21 GAN09981.1 - 7.7e-06 25.4 0.5 0.13 11.6 0.1 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAN09981.1 - 2.3e-05 24.4 0.0 0.034 14.1 0.0 3.4 2 1 1 3 3 3 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 GAN09981.1 - 3.1e-05 24.1 0.0 0.026 14.6 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain CDC48_N PF02359.18 GAN09981.1 - 7.9e-05 22.8 0.0 0.00027 21.0 0.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_28 PF13521.6 GAN09981.1 - 0.00011 22.5 0.0 0.072 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAN09981.1 - 0.00018 21.1 0.0 0.2 11.2 0.0 3.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 GAN09981.1 - 0.00024 21.6 0.0 0.075 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 GAN09981.1 - 0.00083 19.1 0.1 0.56 9.9 0.0 3.9 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 GAN09981.1 - 0.0015 18.2 2.6 5.1 6.6 0.2 3.6 3 1 0 3 3 3 0 AAA domain AAA_3 PF07726.11 GAN09981.1 - 0.0015 18.4 0.0 3.1 7.6 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 GAN09981.1 - 0.0024 17.2 2.5 1 8.7 0.1 3.3 3 1 0 3 3 3 2 KaiC AAA_24 PF13479.6 GAN09981.1 - 0.003 17.3 0.0 0.48 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAN09981.1 - 0.0083 15.4 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 GAN09981.1 - 0.0099 15.1 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 GAN09981.1 - 0.012 15.1 0.0 0.55 9.6 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 GAN09981.1 - 0.023 13.8 0.0 0.97 8.5 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 GAN09981.1 - 0.026 14.5 1.2 14 5.6 0.0 3.8 4 0 0 4 4 4 0 NACHT domain IPT PF01745.16 GAN09981.1 - 0.026 13.9 0.2 0.51 9.7 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase ABC_tran PF00005.27 GAN09981.1 - 0.03 14.8 0.0 2.1 8.9 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 GAN09981.1 - 0.085 12.6 0.0 4.4 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GAN09981.1 - 0.11 12.1 0.0 0.68 9.5 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 GAN09981.1 - 0.2 11.4 0.2 2.2 8.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain VPS13_mid_rpt PF16910.5 GAN09983.1 - 3.2e-77 259.1 17.8 5.2e-76 255.2 0.8 5.5 5 1 1 6 6 6 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 GAN09983.1 - 1e-75 254.6 3.6 3.8e-74 249.5 1.0 3.5 2 1 1 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 GAN09983.1 - 1.1e-73 246.8 2.8 7.1e-67 224.6 0.1 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 GAN09983.1 - 4.5e-73 245.9 10.0 8.9e-71 238.4 1.5 4.8 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 GAN09983.1 - 1.3e-38 131.6 0.1 5.9e-38 129.6 0.1 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAN09983.1 - 7.1e-10 39.1 0.0 2.2e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain CASP_C PF08172.12 GAN09984.1 - 6.9e-69 232.0 1.3 6.9e-69 232.0 1.3 4.2 3 1 0 4 4 4 1 CASP C terminal Sec34 PF04136.15 GAN09984.1 - 0.0063 16.4 3.2 0.0063 16.4 3.2 6.2 5 2 2 7 7 7 1 Sec34-like family Jnk-SapK_ap_N PF09744.9 GAN09984.1 - 0.12 12.6 60.9 0.12 12.6 12.6 4.6 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 GAN09984.1 - 0.67 10.4 72.3 0.13 12.7 2.7 7.4 5 2 2 7 7 7 0 Cell division protein ZapB FlaC_arch PF05377.11 GAN09984.1 - 1.7 9.1 38.2 0.16 12.4 0.4 7.8 6 1 3 9 9 9 0 Flagella accessory protein C (FlaC) YabA PF06156.13 GAN09984.1 - 6.4 7.5 50.5 0.71 10.5 0.3 6.8 3 1 3 6 6 6 0 Initiation control protein YabA Dicty_REP PF05086.12 GAN09985.1 - 2.5 6.0 3.4 2.3 6.1 3.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BRO1 PF03097.18 GAN09986.1 - 1.6e-129 432.2 3.7 1.6e-129 432.2 3.7 2.2 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAN09986.1 - 2.9e-59 200.8 13.8 7.8e-59 199.4 13.8 1.8 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CorA PF01544.18 GAN09986.1 - 6 6.1 11.3 1.5e+02 1.5 11.3 2.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Thaumatin PF00314.17 GAN09987.1 - 6.3e-46 156.7 14.9 3.9e-45 154.1 14.9 1.9 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 GAN09987.1 - 2.4e-07 30.4 2.6 0.26 10.5 0.0 3.1 3 0 0 3 3 3 3 Beta-1,3-glucanase Zn_clus PF00172.18 GAN09988.1 - 2.2e-07 30.9 24.3 0.00014 21.9 3.7 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 GAN09988.1 - 0.88 9.9 14.3 1.1 9.6 4.5 2.9 2 0 0 2 2 2 0 Opy2 protein F-box PF00646.33 GAN09989.1 - 0.026 14.4 0.5 0.081 12.8 0.1 2.0 2 0 0 2 2 2 0 F-box domain PH PF00169.29 GAN09992.1 - 0.0011 19.5 0.0 0.0038 17.7 0.0 2.0 1 0 0 1 1 1 1 PH domain MtrB PF05440.12 GAN09992.1 - 0.017 15.5 1.9 0.96 9.9 0.1 3.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B bZIP_1 PF00170.21 GAN09992.1 - 0.026 14.6 0.5 0.026 14.6 0.5 7.7 6 3 2 8 8 8 0 bZIP transcription factor DUF4358 PF14270.6 GAN09992.1 - 0.038 14.3 0.3 0.038 14.3 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) RasGEF PF00617.19 GAN09993.1 - 4e-13 50.0 2.3 4.7e-13 49.7 0.4 2.0 1 1 0 2 2 2 1 RasGEF domain YojJ PF10372.9 GAN09993.1 - 0.16 12.0 1.3 0.52 10.5 1.3 1.9 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus YEATS PF03366.16 GAN09994.1 - 1.9e-23 82.2 0.3 4.6e-23 81.0 0.3 1.7 1 0 0 1 1 1 1 YEATS family DUF3829 PF12889.7 GAN09995.1 - 0.15 11.5 0.3 0.29 10.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Med3 PF11593.8 GAN09996.1 - 0.64 9.2 5.9 1.3 8.1 5.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ESSS PF10183.9 GAN09999.1 - 3.2e-11 43.4 0.0 3.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Skp1_POZ PF03931.15 GAN10000.1 - 9.5e-10 38.5 0.0 2.3e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 GAN10000.1 - 0.019 15.2 0.0 0.026 14.8 0.0 1.3 1 1 0 1 1 1 0 BTB/POZ domain Pyr_redox_2 PF07992.14 GAN10002.1 - 2.2e-68 230.7 5.9 3.6e-68 230.0 5.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAN10002.1 - 5.3e-41 139.3 0.0 2e-40 137.5 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAN10002.1 - 1.5e-18 67.1 6.8 6.1e-17 62.0 1.7 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN10002.1 - 2.1e-12 46.9 4.6 2.5e-09 36.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN10002.1 - 1.1e-11 44.8 8.6 8.1e-11 41.9 0.2 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 GAN10002.1 - 6.4e-11 42.0 5.7 5.5e-10 38.9 0.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A MFS_2 PF13347.6 GAN10002.1 - 1.4e-09 37.0 24.8 3.1e-08 32.6 19.7 3.4 2 1 0 2 2 2 1 MFS/sugar transport protein Thi4 PF01946.17 GAN10002.1 - 2e-07 30.5 0.4 6.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 GAN10002.1 - 4.2e-07 29.4 0.9 4.2e-07 29.4 0.9 4.5 4 1 2 6 6 6 1 FAD binding domain NAD_binding_8 PF13450.6 GAN10002.1 - 1.8e-05 24.9 4.3 0.0013 18.9 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAN10002.1 - 0.00011 21.6 8.9 0.019 14.2 0.3 3.3 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 GAN10002.1 - 0.00019 20.8 2.4 0.013 14.8 0.3 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAN10002.1 - 0.00024 19.9 13.8 0.00032 19.5 0.5 4.0 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 GAN10002.1 - 0.001 18.3 0.1 0.49 9.5 0.1 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 GAN10002.1 - 0.25 10.9 2.2 0.28 10.8 0.3 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAN10002.1 - 0.33 10.8 6.6 0.058 13.3 0.8 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 GAN10002.1 - 0.34 10.4 14.3 0.41 10.2 0.1 3.8 3 1 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAN10002.1 - 1.3 8.0 3.2 2.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein eIF3_N PF09440.10 GAN10003.1 - 1.1e-47 161.8 6.3 1.1e-47 161.8 6.3 3.1 3 1 0 4 4 4 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GAN10003.1 - 2.9e-16 59.9 0.6 3.7e-15 56.3 0.2 2.5 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 GAN10003.1 - 0.0017 18.3 2.4 0.029 14.4 0.2 2.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 GAN10003.1 - 0.0054 16.5 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 26S proteasome subunit RPN7 EF-hand_7 PF13499.6 GAN10003.1 - 0.22 12.0 1.6 2.5 8.6 0.3 2.9 2 0 0 2 2 2 0 EF-hand domain pair GPAT_N PF14829.6 GAN10004.1 - 0.11 12.5 0.4 0.19 11.8 0.3 1.5 1 1 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal ACT_7 PF13840.6 GAN10006.1 - 2.5e-25 88.1 0.2 4.8e-11 42.3 0.0 3.1 3 0 0 3 3 3 2 ACT domain Lipase_3 PF01764.25 GAN10006.1 - 9.1e-17 61.3 0.0 6.3e-10 39.1 0.1 2.7 2 0 0 2 2 2 2 Lipase (class 3) Castor1_N PF18700.1 GAN10006.1 - 0.00018 21.2 0.2 0.0089 15.8 0.1 2.5 2 0 0 2 2 2 1 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain GYF PF02213.16 GAN10007.1 - 9.5e-18 63.6 0.2 2.5e-17 62.3 0.2 1.8 1 0 0 1 1 1 1 GYF domain SPOUT_MTase PF02590.17 GAN10007.1 - 0.041 13.8 2.0 0.12 12.3 2.0 1.7 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase GYF_2 PF14237.6 GAN10007.1 - 0.048 13.5 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 GYF domain 2 Herpes_UL92 PF03048.14 GAN10007.1 - 0.77 9.5 2.4 1.4 8.7 2.4 1.3 1 0 0 1 1 1 0 UL92 family RicinB_lectin_2 PF14200.6 GAN10008.1 - 1.3e-12 48.3 1.2 2.8e-06 28.0 0.1 3.0 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAN10008.1 - 5.8e-10 39.5 0.1 4.5e-06 26.9 0.0 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain DNA_pol3_chi PF04364.13 GAN10008.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC 4HBT_3 PF13622.6 GAN10009.1 - 1.4e-29 104.1 0.0 2e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily FMN_red PF03358.15 GAN10009.1 - 7.4e-25 87.5 0.0 1.5e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAN10009.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold CLTH PF10607.9 GAN10010.1 - 2.8e-36 124.6 0.3 8.2e-36 123.1 0.3 1.9 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.27 GAN10010.1 - 3.1e-28 97.1 12.0 2.5e-14 52.6 2.5 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 GAN10010.1 - 1.6e-11 43.8 1.7 5.5e-11 42.1 1.7 2.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 GAN10010.1 - 0.00095 19.2 5.9 1.6 8.9 0.1 4.3 4 0 0 4 4 4 2 Zinc ribbon domain zf-RRPl_C4 PF17026.5 GAN10010.1 - 1.6 8.9 11.4 0.17 12.0 1.4 3.7 3 1 1 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type ACCA PF03255.14 GAN10010.1 - 2.6 7.9 6.5 3.3 7.6 1.9 2.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Mitofilin PF09731.9 GAN10010.1 - 3.5 6.4 13.7 0.075 11.9 5.4 2.3 2 1 1 3 3 3 0 Mitochondrial inner membrane protein zf-ribbon_3 PF13248.6 GAN10010.1 - 3.5 7.2 16.2 1.2 8.6 0.2 5.1 5 0 0 5 5 5 0 zinc-ribbon domain Rpr2 PF04032.16 GAN10010.1 - 9.8 6.5 12.3 3.5 8.0 0.9 4.3 2 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CHY PF05495.12 GAN10011.1 - 1.1e-08 35.4 13.9 1.1e-08 35.4 13.9 3.9 3 1 1 4 4 4 1 CHY zinc finger RWD PF05773.22 GAN10011.1 - 0.00042 20.6 0.1 0.9 9.8 0.1 2.6 2 0 0 2 2 2 2 RWD domain Izumo-Ig PF16706.5 GAN10011.1 - 0.041 14.0 0.0 1.3 9.1 0.0 3.0 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DASH_Dad1 PF08649.10 GAN10011.1 - 0.11 12.7 1.2 16 5.8 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad1 zf-CSL PF05207.13 GAN10011.1 - 0.41 10.4 4.2 0.6 9.9 0.2 2.9 2 0 0 2 2 2 0 CSL zinc finger RRM_1 PF00076.22 GAN10012.1 - 2.1e-16 59.5 0.0 3.2e-12 46.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 GAN10013.1 - 1e-103 347.7 30.0 8.2e-102 341.4 30.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN10013.1 - 9.7e-27 93.8 24.3 9.7e-27 93.8 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3046 PF11248.8 GAN10013.1 - 0.073 13.4 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) ORF6C PF10552.9 GAN10013.1 - 0.2 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 ORF6C domain Glug PF07581.12 GAN10013.1 - 0.33 11.4 2.3 1.6 9.3 2.3 2.2 1 0 0 1 1 1 0 The GLUG motif Pkinase PF00069.25 GAN10014.1 - 2.5e-40 138.5 0.0 1.2e-39 136.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10014.1 - 2.4e-37 128.7 0.0 1.5e-36 126.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.27 GAN10014.1 - 1e-06 28.3 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF2753 PF10952.8 GAN10014.1 - 0.0036 17.4 0.1 0.0068 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) RRM_1 PF00076.22 GAN10015.1 - 6.2e-18 64.4 0.3 8.9e-18 63.9 0.3 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN10015.1 - 0.0003 20.6 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 GAN10015.1 - 0.0004 20.0 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAN10015.1 - 0.037 14.0 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAN10015.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF515 PF04415.12 GAN10015.1 - 1.5 7.1 10.9 15 3.8 8.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) ATP-synt_C PF00137.21 GAN10017.1 - 8.9e-35 118.8 34.5 2.2e-23 82.4 14.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 GAN10017.1 - 1 9.1 5.5 2.9 7.6 1.2 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DS PF01916.17 GAN10018.1 - 7.4e-134 445.5 0.0 8.5e-134 445.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase HAD PF12710.7 GAN10018.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ubiquitin PF00240.23 GAN10020.1 - 1.1e-06 28.2 0.1 2.2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAN10020.1 - 0.0002 21.9 3.6 0.0002 21.9 3.6 2.4 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAN10020.1 - 0.0011 19.0 0.1 0.0011 19.0 0.1 2.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like UPF0227 PF05728.12 GAN10020.1 - 2.1 8.2 7.9 3.4 7.6 3.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Velvet PF11754.8 GAN10021.1 - 1.3e-39 136.7 9.5 2e-28 100.0 0.3 3.0 2 1 1 3 3 3 2 Velvet factor UPF0047 PF01894.17 GAN10022.1 - 3.3e-38 130.4 0.0 3.8e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 HPP PF04982.13 GAN10023.1 - 1.5e-39 134.9 6.3 2.9e-39 134.0 6.3 1.5 1 0 0 1 1 1 1 HPP family DUF1218 PF06749.12 GAN10023.1 - 0.37 11.3 4.6 0.59 10.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF3792 PF12670.7 GAN10023.1 - 4.7 7.4 10.1 1.4 9.1 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) BAG PF02179.16 GAN10024.1 - 1.2e-10 41.7 0.3 1.2e-10 41.7 0.3 3.5 3 0 0 3 3 3 1 BAG domain NAD_binding_10 PF13460.6 GAN10025.1 - 6.8e-16 58.7 0.0 1.2e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN10025.1 - 2.5e-14 53.4 1.3 1.3e-13 51.1 1.3 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAN10025.1 - 1.2e-05 24.9 0.2 0.00062 19.3 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAN10025.1 - 0.00075 19.8 0.2 0.0019 18.5 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 GAN10025.1 - 0.0032 17.9 0.2 0.0059 17.0 0.2 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAN10025.1 - 0.016 15.6 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 GAN10025.1 - 0.026 14.0 0.1 0.045 13.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 GAN10025.1 - 0.027 14.7 0.4 0.063 13.5 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.15 GAN10025.1 - 0.028 13.6 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAN10025.1 - 0.13 11.2 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAT PF02259.23 GAN10026.1 - 2.5e-124 415.0 1.4 6.3e-124 413.7 1.4 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 GAN10026.1 - 6e-72 242.5 0.2 1.1e-71 241.6 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 GAN10026.1 - 1.9e-66 223.0 8.5 1.5e-60 203.8 0.2 5.6 4 1 1 5 5 5 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 GAN10026.1 - 6.6e-46 154.8 1.6 6.6e-46 154.8 1.6 2.7 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 GAN10026.1 - 2.2e-16 59.4 1.1 7.9e-16 57.6 1.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 GAN10026.1 - 4.2e-13 49.5 8.6 0.018 15.4 0.0 9.7 6 3 3 10 10 10 3 HEAT repeats HEAT PF02985.22 GAN10026.1 - 1.7e-12 46.5 21.8 0.00065 19.8 0.0 10.9 13 0 0 13 13 8 2 HEAT repeat HEAT_EZ PF13513.6 GAN10026.1 - 1.5e-11 44.6 22.8 1.2e-05 25.7 0.2 9.9 10 1 1 11 11 8 2 HEAT-like repeat TPR_19 PF14559.6 GAN10026.1 - 2.3e-07 31.2 0.5 0.059 13.9 0.3 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat V-ATPase_H_N PF03224.14 GAN10026.1 - 2.8e-06 26.9 2.8 0.075 12.3 0.1 3.9 4 0 0 4 4 4 2 V-ATPase subunit H CLASP_N PF12348.8 GAN10026.1 - 1.1e-05 25.1 0.3 3.2 7.2 0.0 5.3 4 2 0 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 GAN10026.1 - 2.8e-05 24.2 4.6 0.0072 16.4 0.1 5.3 4 2 2 6 6 5 1 non-SMC mitotic condensation complex subunit 1 TPR_16 PF13432.6 GAN10026.1 - 2.8e-05 24.7 5.1 0.17 12.6 0.6 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat MMS19_C PF12460.8 GAN10026.1 - 2.9e-05 23.4 1.4 0.47 9.5 0.2 4.1 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 GAN10026.1 - 2.9e-05 22.8 11.0 0.33 9.4 0.5 6.1 5 1 0 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 GAN10026.1 - 0.00011 22.8 6.1 45 4.7 0.0 7.9 7 2 2 9 9 8 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 GAN10026.1 - 0.00019 21.1 5.8 0.64 9.5 0.0 5.1 3 1 2 5 5 4 2 Tti2 family Sec7_N PF12783.7 GAN10026.1 - 0.00055 19.9 0.1 0.45 10.4 0.0 4.7 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ANAPC3 PF12895.7 GAN10026.1 - 0.0078 16.4 0.8 2.6 8.4 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 IFRD PF05004.13 GAN10026.1 - 0.01 15.0 0.3 1.8 7.6 0.0 3.8 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) TPR_12 PF13424.6 GAN10026.1 - 0.032 14.5 2.3 8.3 6.8 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10026.1 - 0.033 14.3 5.8 12 6.3 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat T_hemolysin PF12261.8 GAN10026.1 - 0.04 13.7 0.1 0.22 11.3 0.0 2.3 2 0 0 2 2 1 0 Thermostable hemolysin SRP_TPR_like PF17004.5 GAN10026.1 - 0.3 11.1 1.6 1.4 9.0 0.3 2.7 3 0 0 3 3 2 0 Putative TPR-like repeat TPR_7 PF13176.6 GAN10026.1 - 0.32 11.1 3.2 6.6 7.0 0.2 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat KCH PF16944.5 GAN10027.1 - 2.2e-79 266.8 11.7 2.6e-79 266.6 11.7 1.1 1 0 0 1 1 1 1 Fungal potassium channel DctQ PF04290.12 GAN10027.1 - 0.15 11.9 5.3 0.098 12.6 1.3 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sel1 PF08238.12 GAN10029.1 - 9.7e-101 327.9 84.6 2.6e-06 27.9 0.1 29.7 30 1 0 30 30 30 21 Sel1 repeat TPR_12 PF13424.6 GAN10029.1 - 0.0004 20.6 0.4 0.0004 20.6 0.4 11.9 11 3 1 12 12 12 2 Tetratricopeptide repeat TipAS PF07739.13 GAN10029.1 - 0.15 12.6 7.4 2.7 8.6 0.8 3.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Roughex PF06020.11 GAN10029.1 - 0.3 10.2 3.7 0.74 8.9 3.7 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Oxysterol_BP PF01237.18 GAN10030.1 - 3e-70 237.0 3.3 3.4e-68 230.2 3.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L14 PF00238.19 GAN10031.1 - 2.1e-35 121.4 0.2 3.2e-35 120.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.22 GAN10032.1 - 5e-38 128.8 0.2 3.3e-16 58.8 0.2 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAN10032.1 - 1.3e-12 47.7 1.2 1.1e-08 35.1 0.0 3.0 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 GAN10032.1 - 1e-06 28.7 0.1 0.35 11.0 0.0 3.8 3 0 0 3 3 3 3 Limkain b1 RRN9 PF10680.9 GAN10032.1 - 0.013 15.7 0.2 0.07 13.4 0.2 2.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Pkinase PF00069.25 GAN10033.1 - 1.1e-29 103.7 0.1 2.5e-27 95.9 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain DUF3543 PF12063.8 GAN10033.1 - 1.6e-15 57.2 0.9 3.6e-15 56.0 0.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 GAN10033.1 - 1.1e-13 51.0 0.0 1e-11 44.6 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Rrn6 PF10214.9 GAN10034.1 - 0.04 12.4 0.2 0.04 12.4 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Mito_carr PF00153.27 GAN10035.1 - 4.2e-61 202.9 2.6 3.2e-22 78.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 GAN10036.1 - 3.2e-43 148.0 0.0 1.2e-30 106.8 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10036.1 - 2.4e-27 95.9 0.0 9.1e-27 94.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN10036.1 - 1.2e-09 37.5 0.0 2.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAN10036.1 - 0.0012 18.3 0.0 0.004 16.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAN10036.1 - 0.41 10.5 5.1 0.19 11.6 1.8 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF4996 PF16387.5 GAN10037.1 - 0.056 13.9 0.1 0.15 12.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function PIF1 PF05970.14 GAN10039.1 - 4.1e-10 39.4 0.4 7.2e-10 38.6 0.4 1.4 1 1 0 1 1 1 1 PIF1-like helicase TPR_MLP1_2 PF07926.12 GAN10040.1 - 0.02 15.0 0.2 0.037 14.1 0.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein dCache_1 PF02743.18 GAN10040.1 - 0.021 14.6 0.3 0.037 13.8 0.3 1.4 1 0 0 1 1 1 0 Cache domain K-box PF01486.17 GAN10040.1 - 0.074 13.2 1.3 0.18 12.0 1.3 1.6 1 0 0 1 1 1 0 K-box region MukF_M PF17192.4 GAN10040.1 - 0.079 12.7 0.3 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 MukF middle domain TSC22 PF01166.18 GAN10040.1 - 0.082 13.2 0.8 0.29 11.5 0.4 2.2 1 1 0 1 1 1 0 TSC-22/dip/bun family Occludin_ELL PF07303.13 GAN10040.1 - 0.14 12.9 0.4 0.43 11.3 0.4 1.7 1 0 0 1 1 1 0 Occludin homology domain Pex14_N PF04695.13 GAN10040.1 - 0.28 11.8 8.0 0.05 14.3 2.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ocnus PF05005.15 GAN10043.1 - 0.028 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) GH115_C PF17829.1 GAN10044.1 - 0.043 13.7 0.0 0.046 13.6 0.0 1.0 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain Paramyxo_P_V_N PF13825.6 GAN10045.1 - 0.82 9.0 9.1 1.2 8.4 9.1 1.3 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Phage_fiber_2 PF03406.13 GAN10047.1 - 0.11 12.1 1.0 0.15 11.6 1.0 1.2 1 0 0 1 1 1 0 Phage tail fibre repeat TPP_enzyme_N PF02776.18 GAN10048.1 - 4e-31 107.9 0.0 7.3e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAN10048.1 - 2.2e-20 72.8 0.0 7.9e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAN10048.1 - 1.7e-18 66.9 0.0 1.3e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.12 GAN10048.1 - 0.021 15.1 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF362) MFS_1_like PF12832.7 GAN10048.1 - 0.076 11.9 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 MFS_1 like family CO_dh PF02552.16 GAN10048.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Proteasome PF00227.26 GAN10049.1 - 4.9e-52 176.2 0.0 5.9e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAN10049.1 - 1.7e-12 46.8 0.0 3.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SARAF PF06682.12 GAN10050.1 - 0.00082 19.1 0.0 0.00092 19.0 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RCR PF12273.8 GAN10050.1 - 0.005 17.5 0.2 0.0071 17.0 0.2 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF3989 PF13150.6 GAN10050.1 - 0.0087 15.8 0.3 0.013 15.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3989) DUF1201 PF06716.11 GAN10050.1 - 0.024 14.6 0.2 0.035 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) DUF4834 PF16118.5 GAN10050.1 - 0.057 14.4 1.0 0.098 13.6 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) HemY_N PF07219.13 GAN10050.1 - 0.11 12.7 0.3 0.15 12.2 0.3 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Vpu PF00558.19 GAN10050.1 - 0.15 11.8 0.4 0.24 11.2 0.4 1.3 1 0 0 1 1 1 0 Vpu protein DUF5305 PF17231.2 GAN10050.1 - 0.17 11.2 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) FeoB_associated PF12669.7 GAN10050.1 - 1.1 9.7 4.6 1.7 9.1 4.6 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein PfkB PF00294.24 GAN10051.1 - 5.7e-41 140.8 0.3 6.9e-41 140.5 0.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NPCBM_assoc PF10633.9 GAN10052.1 - 0.0018 18.5 0.0 1.2 9.4 0.0 2.6 2 1 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase E1_DerP2_DerF2 PF02221.15 GAN10052.1 - 0.031 14.7 0.1 0.05 14.0 0.1 1.5 1 1 0 1 1 1 0 ML domain Lactamase_B_2 PF12706.7 GAN10053.1 - 2.4e-27 95.8 0.0 2.9e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAN10053.1 - 2.8e-05 24.2 2.3 4.7e-05 23.5 0.8 2.0 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 GAN10053.1 - 0.037 13.9 0.0 0.14 12.0 0.0 1.8 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Cystatin PF00031.21 GAN10053.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Cystatin domain Hexokinase_2 PF03727.16 GAN10054.1 - 6.3e-76 255.0 0.1 9.4e-76 254.4 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAN10054.1 - 6.3e-52 176.4 0.0 9.5e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Cys_Met_Meta_PP PF01053.20 GAN10054.1 - 0.039 12.5 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Oxysterol_BP PF01237.18 GAN10055.1 - 2e-54 184.9 5.6 4.4e-47 160.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein GBP_C PF02841.14 GAN10055.1 - 0.032 13.7 0.8 0.045 13.2 0.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain VPS9 PF02204.18 GAN10056.1 - 1e-33 115.6 0.6 4.5e-33 113.6 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAN10056.1 - 1.3e-09 38.3 4.9 4.3e-05 23.7 0.1 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF5601) CUE PF02845.16 GAN10056.1 - 3.5e-05 23.4 0.1 8.4e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 CUE domain ACBP PF00887.19 GAN10057.1 - 4.9e-26 90.8 0.3 5.4e-26 90.6 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 GAN10057.1 - 0.0096 16.3 0.1 2.2 8.7 0.0 2.0 1 1 1 2 2 2 2 FERM central domain ADH_zinc_N PF00107.26 GAN10058.1 - 2.4e-23 82.5 0.0 4.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN10058.1 - 2.8e-18 67.3 0.0 5.8e-18 66.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN10058.1 - 9.6e-11 41.5 0.1 3e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAN10058.1 - 0.00036 20.4 0.1 0.00068 19.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 GAN10058.1 - 0.044 14.0 0.2 0.089 13.1 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain zf-RVT PF13966.6 GAN10059.1 - 8.3e-07 29.6 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase AAA PF00004.29 GAN10061.1 - 1.4e-41 142.1 0.0 3.2e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN10061.1 - 1e-08 34.8 0.1 2.7e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAN10061.1 - 1.7e-05 24.8 0.1 9.7e-05 22.4 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAN10061.1 - 9.4e-05 22.7 0.0 0.0052 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GAN10061.1 - 0.00017 22.0 0.1 0.0031 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GAN10061.1 - 0.00024 21.3 0.1 0.00089 19.4 0.0 2.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAN10061.1 - 0.00037 19.7 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAN10061.1 - 0.0027 17.5 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAN10061.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 GAN10061.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAN10061.1 - 0.022 14.9 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAN10061.1 - 0.034 14.5 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 GAN10061.1 - 0.035 14.0 0.2 6.7 6.5 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 GAN10061.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAN10061.1 - 0.041 13.6 0.1 0.12 12.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 GAN10061.1 - 0.045 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 GAN10061.1 - 0.061 13.9 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAN10061.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 GAN10061.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 GAN10061.1 - 0.088 12.8 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAN10061.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 GAN10061.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Acyltransferase PF01553.21 GAN10062.1 - 4.9e-10 39.2 0.1 1.4e-09 37.7 0.1 1.6 1 1 1 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 GAN10063.1 - 2.6e-15 56.3 0.1 4.4e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 GAN10063.1 - 0.00018 21.2 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF212 PF02681.14 GAN10063.1 - 0.23 11.6 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 Divergent PAP2 family TP_methylase PF00590.20 GAN10064.1 - 9.6e-44 149.9 0.1 1.9e-43 148.9 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 GAN10064.1 - 3.5e-21 74.6 0.1 7.1e-21 73.6 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 GAN10064.1 - 1.8e-13 50.8 0.0 4.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 GAN10064.1 - 2e-10 39.9 0.5 3.6e-10 39.1 0.5 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TFIIA PF03153.13 GAN10065.1 - 0.076 13.0 7.3 0.14 12.1 7.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1848 PF08902.11 GAN10065.1 - 0.078 12.7 1.7 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1848) Tom22 PF04281.13 GAN10065.1 - 0.24 11.2 2.3 0.61 9.9 2.3 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Med3 PF11593.8 GAN10065.1 - 3.2 6.8 17.9 2.6 7.1 14.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal AAA PF00004.29 GAN10066.1 - 1.6e-49 167.7 0.0 3e-36 124.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN10066.1 - 3.6e-17 61.9 0.4 7.2e-12 44.9 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAN10066.1 - 9.5e-13 48.9 3.2 0.00028 21.3 0.0 4.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAN10066.1 - 3.4e-09 36.8 0.1 0.0016 18.4 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAN10066.1 - 2.4e-08 34.3 2.9 0.027 14.8 0.0 4.8 2 2 2 4 4 4 2 AAA domain DUF815 PF05673.13 GAN10066.1 - 1.3e-07 31.0 0.0 0.0091 15.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAN10066.1 - 7e-07 29.1 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 GAN10066.1 - 7.5e-07 29.2 3.5 0.31 11.0 0.0 3.7 2 2 2 4 4 4 3 NACHT domain AAA_33 PF13671.6 GAN10066.1 - 1.5e-06 28.4 0.1 0.032 14.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAN10066.1 - 2e-06 27.5 0.0 0.055 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAN10066.1 - 3.4e-06 26.9 0.0 0.096 12.4 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_30 PF13604.6 GAN10066.1 - 1.8e-05 24.5 0.1 0.049 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 GAN10066.1 - 2.2e-05 25.0 0.4 0.13 12.8 0.0 3.2 2 1 0 2 2 2 2 ABC transporter RuvB_N PF05496.12 GAN10066.1 - 2.6e-05 24.0 0.0 0.00054 19.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAN10066.1 - 2.8e-05 24.5 0.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 GAN10066.1 - 4.5e-05 22.8 0.1 0.0037 16.5 0.0 2.7 3 0 0 3 3 3 1 TIP49 P-loop domain TsaE PF02367.17 GAN10066.1 - 4.8e-05 23.4 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GAN10066.1 - 4.8e-05 23.9 0.1 0.18 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAN10066.1 - 0.00011 21.7 0.3 0.016 14.6 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 GAN10066.1 - 0.00018 21.9 1.0 1.4 9.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.14 GAN10066.1 - 0.00033 20.8 0.0 0.012 15.7 0.0 2.8 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) MCM PF00493.23 GAN10066.1 - 0.00037 19.7 0.0 0.17 11.0 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain Zeta_toxin PF06414.12 GAN10066.1 - 0.00039 19.8 0.3 0.32 10.3 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.6 GAN10066.1 - 0.00044 20.3 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GAN10066.1 - 0.00061 19.3 0.1 0.057 12.9 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 GAN10066.1 - 0.00061 19.4 2.6 0.85 9.2 0.3 3.8 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 GAN10066.1 - 0.00083 19.0 0.0 0.93 9.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 GAN10066.1 - 0.00096 19.4 0.4 0.36 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 GAN10066.1 - 0.001 18.5 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 KaiC DAP3 PF10236.9 GAN10066.1 - 0.0012 18.1 0.0 0.088 12.0 0.0 2.6 3 0 0 3 3 2 1 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 GAN10066.1 - 0.0012 18.2 0.1 0.7 9.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 GAN10066.1 - 0.0013 18.5 0.1 0.46 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 GAN10066.1 - 0.0019 17.6 0.0 0.42 10.0 0.0 3.1 3 1 0 3 3 3 1 Bacterial TniB protein Bac_DnaA PF00308.18 GAN10066.1 - 0.002 18.0 0.6 0.42 10.4 0.4 2.9 2 1 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.15 GAN10066.1 - 0.0023 17.9 0.1 3.8 7.4 0.0 3.4 2 2 1 4 4 4 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 GAN10066.1 - 0.0024 18.0 0.0 0.19 11.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAN10066.1 - 0.0083 16.0 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 GAN10066.1 - 0.012 14.7 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RsgA_GTPase PF03193.16 GAN10066.1 - 0.015 15.2 0.0 0.63 9.9 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 GAN10066.1 - 0.022 15.0 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FANCI_HD2 PF14680.6 GAN10066.1 - 0.025 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 FANCI helical domain 2 AAA_11 PF13086.6 GAN10066.1 - 0.036 13.9 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GAN10066.1 - 0.039 13.6 0.0 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.21 GAN10066.1 - 0.05 13.3 0.2 2.5 7.7 0.0 3.0 3 0 0 3 3 3 0 Guanylate kinase AAA_17 PF13207.6 GAN10066.1 - 0.053 13.9 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 GAN10066.1 - 0.067 12.1 0.1 7.9 5.3 0.0 3.1 3 0 0 3 3 3 0 AFG1-like ATPase cobW PF02492.19 GAN10066.1 - 0.1 12.2 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Torsin PF06309.11 GAN10066.1 - 0.12 12.4 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Torsin CTP_synth_N PF06418.14 GAN10067.1 - 3.8e-124 413.2 0.0 5e-124 412.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GAN10067.1 - 2.8e-61 206.6 0.0 4.5e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAN10067.1 - 6.6e-06 26.0 0.1 2e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 GAN10067.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L13 PF00572.18 GAN10069.1 - 3.7e-10 40.1 0.0 3.4e-08 33.8 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 BRE1 PF08647.11 GAN10070.1 - 0.012 15.6 14.0 0.012 15.6 14.0 6.6 4 2 3 7 7 7 0 BRE1 E3 ubiquitin ligase Fer4_14 PF13394.6 GAN10070.1 - 0.92 9.7 0.0 0.92 9.7 0.0 3.5 4 1 1 5 5 5 0 4Fe-4S single cluster domain Ysc84 PF04366.12 GAN10071.1 - 4.8e-33 113.6 0.8 7.4e-33 113.0 0.8 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 GAN10071.1 - 2e-13 49.7 0.1 3.6e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN10071.1 - 7e-12 45.0 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN10071.1 - 3.9e-09 36.1 0.0 7.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mucin PF01456.17 GAN10072.1 - 0.85 9.6 30.6 1.7 8.6 30.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_1 PF00076.22 GAN10073.1 - 0.00016 21.4 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Auxin_inducible PF02519.14 GAN10073.1 - 0.7 10.1 3.9 2.4 8.4 0.0 2.7 2 1 1 3 3 3 0 Auxin responsive protein PRK PF00485.18 GAN10074.1 - 2e-28 99.5 0.0 2.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 GAN10074.1 - 0.0035 17.1 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Cytidylate kinase Pox_A32 PF04665.12 GAN10074.1 - 0.13 11.7 0.3 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein RRM_1 PF00076.22 GAN10075.1 - 3.2e-18 65.3 0.0 1.9e-12 46.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 GAN10075.1 - 0.031 14.3 15.8 0.047 13.7 15.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_7 PF16367.5 GAN10075.1 - 0.074 13.2 0.0 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif Pex14_N PF04695.13 GAN10075.1 - 0.11 13.2 14.6 0.35 11.5 4.4 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.11 GAN10075.1 - 0.95 7.6 14.3 1.3 7.1 14.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4834 PF16118.5 GAN10075.1 - 6.9 7.7 12.4 0.58 11.1 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Macoilin PF09726.9 GAN10075.1 - 7.5 5.0 16.3 1.2 7.7 3.4 2.1 2 0 0 2 2 2 0 Macoilin family DivIC PF04977.15 GAN10075.1 - 9.2 6.1 7.4 20 5.0 7.4 1.5 1 0 0 1 1 1 0 Septum formation initiator SNF2_N PF00176.23 GAN10077.1 - 1.3e-67 228.0 0.0 2.2e-67 227.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN10077.1 - 1e-17 64.5 0.0 3e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 GAN10077.1 - 1.2e-07 31.5 8.3 2.8e-07 30.3 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN10077.1 - 4.1e-07 30.2 9.6 1e-06 28.9 9.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAN10077.1 - 1.2e-06 28.3 11.0 2.3e-06 27.4 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN10077.1 - 1.5e-06 27.9 10.6 3.6e-06 26.7 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN10077.1 - 9.7e-06 25.5 9.2 2.5e-05 24.2 9.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 GAN10077.1 - 1.1e-05 25.5 0.0 3.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 GAN10077.1 - 2.4e-05 24.1 8.3 0.00011 22.0 8.6 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DEAD PF00270.29 GAN10077.1 - 6.6e-05 22.7 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 GAN10077.1 - 6.7e-05 22.8 9.7 0.00014 21.8 9.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAN10077.1 - 0.00027 21.0 9.9 0.00057 20.0 9.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAN10077.1 - 0.043 13.9 3.6 0.083 12.9 3.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAN10077.1 - 0.12 12.2 9.6 0.27 11.1 9.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 GAN10077.1 - 0.16 11.9 1.0 0.37 10.7 1.0 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 GAN10077.1 - 0.27 11.1 5.5 0.66 9.9 5.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.12 GAN10077.1 - 1.4 8.9 6.9 6.3 6.9 6.9 2.0 1 1 0 1 1 1 0 zinc-ribbons peroxidase PF00141.23 GAN10078.1 - 3.5e-40 138.1 0.0 8.4e-40 136.9 0.0 1.6 2 0 0 2 2 2 1 Peroxidase Endomucin PF07010.12 GAN10078.1 - 0.018 15.1 0.7 0.024 14.6 0.7 1.1 1 0 0 1 1 1 0 Endomucin RNA_pol_Rpc4 PF05132.14 GAN10078.1 - 0.098 13.1 2.1 0.15 12.5 2.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 MAP17 PF15807.5 GAN10078.1 - 0.22 11.8 2.0 0.37 11.0 2.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF908 PF06012.12 GAN10078.1 - 2 7.8 6.8 2.9 7.2 6.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Trypan_PARP PF05887.11 GAN10078.1 - 2.4 8.1 7.8 4.4 7.3 7.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BIRC6 PF12356.8 GAN10078.1 - 5.6 6.4 5.5 13 5.2 5.5 1.6 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Presenilin PF01080.17 GAN10078.1 - 6 5.5 5.3 7.9 5.1 5.3 1.1 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 GAN10078.1 - 8.8 6.4 7.5 14 5.7 7.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Borrelia_REV PF03978.13 GAN10079.1 - 0.0076 16.2 0.3 0.0098 15.9 0.3 1.2 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein TPR_MLP1_2 PF07926.12 GAN10079.1 - 0.029 14.5 4.7 0.045 13.8 4.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 GAN10079.1 - 0.2 11.7 6.2 0.29 11.1 0.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit RraA-like PF03737.15 GAN10080.1 - 0.0066 16.6 0.2 0.078 13.1 0.0 2.3 2 0 0 2 2 2 1 Aldolase/RraA LIG3_BRCT PF16759.5 GAN10080.1 - 2.1 8.7 10.7 0.27 11.6 1.7 2.9 2 1 1 3 3 3 0 DNA ligase 3 BRCT domain TbpB_A PF17484.2 GAN10080.1 - 2.4 8.9 9.0 1.7 9.4 4.1 2.3 2 0 0 2 2 2 0 N-Lobe handle Tf-binding protein B TRIC PF05197.13 GAN10081.1 - 0.0019 17.8 0.8 0.0026 17.4 0.8 1.2 1 0 0 1 1 1 1 TRIC channel bZIP_2 PF07716.15 GAN10082.1 - 1.6e-10 40.9 12.2 1.6e-10 40.9 11.0 1.6 1 1 1 2 2 2 2 Basic region leucine zipper Phlebovirus_NSM PF07246.11 GAN10082.1 - 0.013 14.9 4.4 0.019 14.4 4.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TFIIA PF03153.13 GAN10082.1 - 0.031 14.3 12.5 0.035 14.1 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.21 GAN10082.1 - 0.031 14.4 8.4 0.058 13.5 8.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor LMBR1 PF04791.16 GAN10082.1 - 0.83 8.5 4.2 0.97 8.3 4.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ytp1 PF10355.9 GAN10083.1 - 1.4e-68 231.1 1.2 2.3e-68 230.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAN10083.1 - 3.5e-07 30.0 1.5 3.5e-07 30.0 1.5 4.5 4 1 1 5 5 5 2 Domain of unknown function (DUF2427) DUF4059 PF13268.6 GAN10083.1 - 0.14 12.6 1.2 18 5.8 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Tetraspanin PF00335.20 GAN10083.1 - 0.2 11.4 3.6 0.86 9.3 0.4 2.8 3 0 0 3 3 3 0 Tetraspanin family DUF2852 PF11014.8 GAN10083.1 - 0.42 10.8 2.3 29 4.9 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) OPT PF03169.15 GAN10083.1 - 1.7 7.2 8.7 0.17 10.5 2.5 2.1 2 1 1 3 3 3 0 OPT oligopeptide transporter protein DUF4079 PF13301.6 GAN10083.1 - 9.6 6.4 12.5 0.52 10.5 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4079) zf-RVT PF13966.6 GAN10084.1 - 0.00084 20.0 0.5 0.0019 18.9 0.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1211 PF06736.11 GAN10084.1 - 0.056 13.9 1.2 0.08 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) DUF2964 PF11177.8 GAN10084.1 - 0.079 13.2 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) FMN_red PF03358.15 GAN10085.1 - 7.9e-13 48.4 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAN10085.1 - 2.4e-06 27.4 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 GAN10085.1 - 0.0074 16.5 0.1 0.5 10.6 0.1 2.9 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 GAN10086.1 - 2.9e-13 49.9 0.0 4.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAN10086.1 - 1.7e-05 24.6 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 GAN10086.1 - 0.051 13.8 0.1 0.14 12.3 0.1 1.8 1 1 0 1 1 1 0 Flavodoxin Lep_receptor_Ig PF06328.11 GAN10087.1 - 0.32 11.0 1.7 4.3 7.4 0.1 2.1 1 1 1 2 2 2 0 Ig-like C2-type domain RT_RNaseH PF17917.1 GAN10088.1 - 3.5e-30 104.4 0.0 6.4e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN10088.1 - 1.9e-29 101.6 0.1 4.2e-29 100.5 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 GAN10088.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase RHD3 PF05879.12 GAN10090.1 - 5.2e-246 818.4 19.1 2.4e-210 700.5 14.6 2.9 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 GAN10090.1 - 4.1e-06 26.9 0.3 1.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAN10090.1 - 1.9e-05 24.7 0.0 6e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 GAN10090.1 - 2.2e-05 23.9 0.2 4.5e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 GAN10090.1 - 0.01 16.1 0.1 0.032 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAN10090.1 - 0.033 14.1 0.3 0.61 10.0 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase OAR PF03826.17 GAN10090.1 - 0.16 11.9 0.6 0.33 10.9 0.6 1.6 1 0 0 1 1 1 0 OAR domain CompInhib_SCIN PF11546.8 GAN10090.1 - 0.5 10.4 2.5 2.7 8.0 0.6 2.6 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN Arm PF00514.23 GAN10091.1 - 8.2e-07 28.9 10.3 1.3e-06 28.2 0.0 5.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAN10091.1 - 1.7e-06 27.8 0.2 0.0016 18.5 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 GAN10091.1 - 2.6e-06 27.8 3.3 0.00022 21.6 0.2 5.0 4 2 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 GAN10091.1 - 1.3e-05 25.3 1.6 0.00012 22.2 0.0 3.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAN10091.1 - 0.0004 20.7 0.3 0.0077 16.6 0.1 2.9 2 1 0 2 2 2 1 HEAT repeats CLASP_N PF12348.8 GAN10091.1 - 0.021 14.4 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 CLASP N terminal DUF1427 PF07235.11 GAN10091.1 - 0.021 14.7 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) IBN_N PF03810.19 GAN10091.1 - 0.051 13.5 1.2 0.2 11.6 0.3 2.4 2 1 1 3 3 3 0 Importin-beta N-terminal domain V-ATPase_H_C PF11698.8 GAN10091.1 - 0.061 13.4 1.9 13 5.9 0.0 2.9 3 0 0 3 3 3 0 V-ATPase subunit H MFS_1 PF07690.16 GAN10092.1 - 2.2e-13 49.9 32.8 3e-13 49.4 32.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAN10092.1 - 3.6e-12 46.3 1.3 3.6e-12 46.3 1.3 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 zf-RVT PF13966.6 GAN10093.1 - 0.0018 18.9 0.1 0.0039 17.9 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase SWIRM PF04433.17 GAN10094.1 - 7.3e-09 35.8 0.1 3.1e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain SUIM_assoc PF16619.5 GAN10094.1 - 5.7 7.1 8.7 0.27 11.3 2.7 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 GAN10095.1 - 2.4e-13 50.3 10.9 0.00063 20.5 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10095.1 - 7.9e-06 26.1 0.0 0.14 12.5 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAN10095.1 - 0.012 15.5 0.0 1 9.4 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GAN10095.1 - 0.018 13.6 0.0 0.033 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 GAN10095.1 - 0.092 12.1 0.0 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain RhoGAP PF00620.27 GAN10096.1 - 0.00017 21.4 0.1 0.0013 18.5 0.0 2.4 2 1 0 2 2 2 1 RhoGAP domain Homeobox_KN PF05920.11 GAN10097.1 - 1.2e-18 66.7 2.5 1.8e-18 66.2 0.8 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 GAN10097.1 - 6.4e-08 32.3 0.7 6.4e-08 32.3 0.7 2.1 2 0 0 2 2 2 1 Homeodomain Kinesin PF00225.23 GAN10098.1 - 3.6e-100 335.1 1.2 3.6e-100 335.1 1.2 4.6 5 1 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 GAN10098.1 - 8.9e-17 61.4 13.3 1e-14 54.7 0.0 5.1 5 0 0 5 5 5 2 Microtubule binding Ribosomal_L4 PF00573.22 GAN10099.1 - 7e-39 133.5 0.2 1.2e-38 132.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAN10099.1 - 2e-30 104.7 6.4 2.9e-29 100.9 3.6 2.6 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain USP8_dimer PF08969.11 GAN10100.1 - 1.7e-13 50.8 6.2 2.7e-13 50.1 0.8 2.1 1 1 1 2 2 2 2 USP8 dimerisation domain Guanylate_kin PF00625.21 GAN10100.1 - 0.044 13.5 0.6 0.26 11.0 0.0 1.9 1 1 0 2 2 2 0 Guanylate kinase MFS_1 PF07690.16 GAN10101.1 - 2.4e-21 76.1 41.2 2.4e-21 76.1 41.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN10101.1 - 6.4e-07 28.6 33.7 0.0004 19.4 9.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Phage_holin_5_1 PF06946.11 GAN10101.1 - 3.1 8.3 5.7 14 6.2 0.4 3.1 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 zf-RING_2 PF13639.6 GAN10102.1 - 1.5e-07 31.6 4.0 4.2e-07 30.2 4.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAN10102.1 - 1.4e-05 24.8 4.4 2.3e-05 24.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN10102.1 - 6e-05 22.8 4.7 0.00012 21.9 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN10102.1 - 6.2e-05 22.8 5.1 0.00011 21.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN10102.1 - 8.7e-05 22.7 3.6 0.00021 21.5 2.8 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain Rtf2 PF04641.12 GAN10102.1 - 0.00025 20.5 1.9 0.00029 20.3 1.9 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 GAN10102.1 - 0.00026 20.8 5.0 0.00047 19.9 5.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAN10102.1 - 0.00037 20.5 4.2 0.00037 20.5 4.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAN10102.1 - 0.0006 19.7 5.3 0.0011 18.9 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAN10102.1 - 0.00085 19.0 0.2 0.0022 17.7 0.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAN10102.1 - 0.035 14.1 1.8 0.089 12.9 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAN10102.1 - 0.045 13.6 3.0 0.088 12.6 3.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain JIP_LZII PF16471.5 GAN10102.1 - 0.049 13.8 0.8 5.8 7.2 0.1 2.2 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II zf-RING_6 PF14835.6 GAN10102.1 - 0.16 11.8 2.4 0.29 11.0 2.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 GAN10102.1 - 0.22 11.4 3.7 0.22 11.4 2.3 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2 PF00096.26 GAN10102.1 - 2.4 8.8 9.0 6.1 7.5 0.6 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type CDO_I PF05995.12 GAN10103.1 - 3.6e-46 156.6 0.4 4.8e-45 152.9 0.4 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 GAN10103.1 - 1.7e-05 24.4 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PCO_ADO DUF1775 PF07987.11 GAN10105.1 - 1.4e-38 132.5 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) CBM_15 PF03426.14 GAN10105.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) FtsJ PF01728.19 GAN10106.1 - 3e-35 121.9 0.0 4.9e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Presenilin PF01080.17 GAN10106.1 - 9.2 4.9 11.8 14 4.3 11.8 1.2 1 0 0 1 1 1 0 Presenilin Pro_isomerase PF00160.21 GAN10107.1 - 2.7e-50 170.7 0.2 3e-50 170.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_H2-Ydr279 PF09468.10 GAN10108.1 - 2e-12 47.6 1.2 3.9e-12 46.6 1.2 1.6 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 GAN10108.1 - 3.1e-05 24.2 0.0 8.8e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain zf-C3HC4_3 PF13920.6 GAN10109.1 - 3.4e-16 58.8 11.5 5.3e-16 58.2 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAN10109.1 - 1.3e-06 28.6 12.0 2.2e-06 27.9 12.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAN10109.1 - 1.6e-05 24.7 13.6 2.7e-05 23.9 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN10109.1 - 0.00012 21.9 11.2 0.00022 21.0 11.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TFIIA PF03153.13 GAN10109.1 - 0.00048 20.2 26.6 0.0006 19.9 26.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 GAN10109.1 - 0.00091 19.3 8.6 0.0027 17.8 8.8 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAN10109.1 - 0.0011 18.7 14.7 0.0021 17.9 14.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN10109.1 - 0.0027 17.7 12.3 0.0054 16.7 12.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Armet PF10208.9 GAN10109.1 - 0.0033 17.4 2.7 0.88 9.5 0.0 3.0 3 0 0 3 3 2 1 Degradation arginine-rich protein for mis-folding CDC45 PF02724.14 GAN10109.1 - 0.012 13.9 19.8 0.015 13.7 19.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Caldesmon PF02029.15 GAN10109.1 - 0.028 13.2 29.5 0.035 12.9 29.5 1.1 1 0 0 1 1 1 0 Caldesmon zf-P11 PF03854.14 GAN10109.1 - 0.034 13.8 8.7 0.065 12.9 8.7 1.4 1 0 0 1 1 1 0 P-11 zinc finger PAT1 PF09770.9 GAN10109.1 - 0.11 10.8 31.0 0.14 10.5 31.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF966 PF06136.13 GAN10109.1 - 0.16 11.7 23.3 0.21 11.3 23.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) zinc_ribbon_2 PF13240.6 GAN10109.1 - 0.19 11.5 1.3 0.56 10.0 1.3 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Raftlin PF15250.6 GAN10109.1 - 0.26 10.0 14.4 0.32 9.7 14.4 1.3 1 0 0 1 1 1 0 Raftlin XAP5 PF04921.14 GAN10109.1 - 0.34 10.7 15.6 0.46 10.3 15.6 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator HAUS6_N PF14661.6 GAN10109.1 - 0.41 10.2 17.9 0.64 9.6 17.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RR_TM4-6 PF06459.12 GAN10109.1 - 0.41 10.4 19.1 0.74 9.6 19.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 GAN10109.1 - 0.44 7.6 21.9 0.49 7.5 21.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 GAN10109.1 - 0.54 10.5 17.9 0.88 9.8 17.9 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain zf-rbx1 PF12678.7 GAN10109.1 - 0.59 10.5 7.8 2 8.8 7.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Asp-B-Hydro_N PF05279.11 GAN10109.1 - 0.61 10.1 16.1 0.84 9.7 16.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LAP1C PF05609.12 GAN10109.1 - 0.78 8.8 23.0 0.94 8.5 23.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Borrelia_P83 PF05262.11 GAN10109.1 - 0.97 7.9 18.8 1.3 7.4 18.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-RING_4 PF14570.6 GAN10109.1 - 1.1 9.1 10.5 2.2 8.2 10.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Plasmodium_Vir PF05795.11 GAN10109.1 - 1.7 8.0 12.8 2.4 7.5 12.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nop53 PF07767.11 GAN10109.1 - 2 7.7 34.4 2.7 7.3 34.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF-3_zeta PF05091.12 GAN10109.1 - 2.3 7.1 27.4 3.2 6.6 27.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MDM10 PF12519.8 GAN10109.1 - 3.2 6.5 16.9 4.1 6.2 16.9 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Mem_trans PF03547.18 GAN10109.1 - 4.1 5.7 4.8 4.4 5.6 4.8 1.2 1 0 0 1 1 1 0 Membrane transport protein zf-RING_UBOX PF13445.6 GAN10109.1 - 5.3 7.2 10.3 10 6.2 3.8 2.7 2 0 0 2 2 2 0 RING-type zinc-finger SOBP PF15279.6 GAN10109.1 - 6 7.4 25.6 7.9 7.0 25.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.7 GAN10109.1 - 6.6 4.7 23.3 7.7 4.5 23.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0242 PF06785.11 GAN10109.1 - 6.7 6.8 26.2 10 6.1 26.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1501 PF07394.12 GAN10109.1 - 8 5.4 18.9 11 5.0 18.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Exonuc_VII_L PF02601.15 GAN10109.1 - 9 5.8 20.2 11 5.4 20.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLC12 PF03522.15 GAN10109.1 - 9.5 5.1 22.1 13 4.7 22.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 OPT PF03169.15 GAN10110.1 - 1.2e-185 618.7 55.9 1.4e-185 618.5 55.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Suc_Fer-like PF06999.12 GAN10111.1 - 4.2e-53 180.1 0.1 4.9e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pterin_4a PF01329.19 GAN10112.1 - 3.8e-30 103.9 0.0 4.1e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase AAA_11 PF13086.6 GAN10114.1 - 4.4e-62 210.2 1.3 7.5e-62 209.5 0.3 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 GAN10114.1 - 3.8e-58 196.4 0.2 7.5e-57 192.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAN10114.1 - 1.1e-14 54.6 0.0 3.5e-13 49.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAN10114.1 - 4.3e-12 46.3 0.0 0.0023 17.7 0.0 3.7 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GAN10114.1 - 2.4e-11 44.2 0.0 6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GAN10114.1 - 1.2e-07 31.9 0.0 4.7e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GAN10114.1 - 1.3e-07 31.2 1.4 1.1e-05 24.9 0.6 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 GAN10114.1 - 8.6e-05 22.5 0.2 0.0035 17.2 0.2 2.5 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.6 GAN10114.1 - 0.00013 22.3 0.2 0.0017 18.6 0.2 2.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 GAN10114.1 - 0.00029 20.4 0.1 0.0027 17.3 0.1 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GAN10114.1 - 0.0004 20.8 0.0 0.0016 18.8 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain 4HB_MCP_1 PF12729.7 GAN10114.1 - 0.00091 18.8 0.1 0.0027 17.3 0.1 1.8 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction PIF1 PF05970.14 GAN10114.1 - 0.0011 18.3 0.0 0.09 11.9 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase AAA PF00004.29 GAN10114.1 - 0.0011 19.4 1.8 0.004 17.6 0.2 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAN10114.1 - 0.0018 18.0 0.1 0.0064 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 GAN10114.1 - 0.005 16.6 0.1 0.047 13.5 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 GAN10114.1 - 0.0071 15.8 0.0 0.059 12.8 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 GAN10114.1 - 0.0093 15.9 0.1 0.092 12.6 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAN10114.1 - 0.012 15.7 0.1 0.13 12.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Flavi_DEAD PF07652.14 GAN10114.1 - 0.012 15.6 0.4 0.13 12.3 0.0 2.4 1 1 1 2 2 2 0 Flavivirus DEAD domain ABC_tran PF00005.27 GAN10114.1 - 0.012 16.2 0.1 0.081 13.4 0.0 2.5 1 1 1 2 2 2 0 ABC transporter AAA_25 PF13481.6 GAN10114.1 - 0.018 14.6 1.0 1.4 8.4 0.0 3.1 2 1 1 3 3 3 0 AAA domain UvrD_C PF13361.6 GAN10114.1 - 0.026 13.9 0.5 0.19 11.1 0.0 2.4 2 1 0 3 3 3 0 UvrD-like helicase C-terminal domain TK PF00265.18 GAN10114.1 - 0.05 13.5 1.1 5.7 6.8 0.2 2.8 2 1 1 3 3 3 0 Thymidine kinase AAA_14 PF13173.6 GAN10114.1 - 0.069 13.2 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAN10114.1 - 0.084 13.0 0.2 0.25 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 GAN10114.1 - 0.1 12.3 0.2 2.9 7.5 0.0 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DnaJ PF00226.31 GAN10115.1 - 1.1e-27 95.9 5.2 2.4e-27 94.9 5.2 1.6 1 0 0 1 1 1 1 DnaJ domain Keratin PF02422.16 GAN10115.1 - 0.24 11.1 2.2 0.45 10.2 2.2 1.4 1 0 0 1 1 1 0 Keratin TTL PF03133.15 GAN10116.1 - 1.7e-51 175.2 2.6 2.2e-51 174.8 2.6 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAN10116.1 - 0.0036 16.6 0.3 0.16 11.2 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp UvdE PF03851.14 GAN10117.1 - 6.2e-94 314.3 0.3 1.2e-93 313.4 0.3 1.5 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF3246 PF11596.8 GAN10117.1 - 0.98 8.8 15.2 0.054 12.9 5.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3246) CDC45 PF02724.14 GAN10117.1 - 8.2 4.6 15.1 12 4.0 15.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Acyl_transf_1 PF00698.21 GAN10118.1 - 6.2e-28 98.2 0.7 9.4e-28 97.6 0.7 1.2 1 0 0 1 1 1 1 Acyl transferase domain S4 PF01479.25 GAN10119.1 - 6.4e-12 45.0 0.0 1.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 GAN10119.1 - 6.7e-10 39.7 5.7 9.2e-10 39.3 4.6 1.7 1 1 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain RepC PF06504.11 GAN10119.1 - 0.023 13.9 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Replication protein C (RepC) CENP-O PF09496.10 GAN10119.1 - 0.11 12.4 1.1 0.17 11.8 0.4 1.6 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component YabA PF06156.13 GAN10119.1 - 0.14 12.8 0.8 0.25 12.0 0.8 1.4 1 0 0 1 1 1 0 Initiation control protein YabA MMR_HSR1 PF01926.23 GAN10120.1 - 9.7e-22 77.2 0.1 1.9e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN10120.1 - 3.6e-12 46.2 0.0 5.1e-10 39.2 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN10120.1 - 2e-10 40.8 0.0 0.0001 22.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAN10120.1 - 1.2e-09 37.9 0.0 2.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B KH_2 PF07650.17 GAN10120.1 - 1.3e-09 37.7 0.4 2.6e-09 36.8 0.4 1.5 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.23 GAN10120.1 - 1.4e-09 38.2 0.5 1.8e-06 28.1 0.2 2.5 1 1 1 2 2 2 2 Dynamin family ATP_bind_1 PF03029.17 GAN10120.1 - 3.5e-06 27.0 0.1 0.0003 20.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Arf PF00025.21 GAN10120.1 - 2.9e-05 23.6 0.0 7.6e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AIG1 PF04548.16 GAN10120.1 - 4.1e-05 23.0 0.0 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 GAN10120.1 - 0.00014 21.6 0.0 0.00094 18.9 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 GAN10120.1 - 0.00015 21.4 0.1 0.0061 16.2 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 GAN10120.1 - 0.0026 16.9 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1_Xtn PF16897.5 GAN10120.1 - 0.0035 17.3 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RNA_helicase PF00910.22 GAN10120.1 - 0.0036 17.7 0.2 8.3 6.9 0.0 3.5 2 2 1 3 3 3 1 RNA helicase G-alpha PF00503.20 GAN10120.1 - 0.0039 16.4 0.0 0.44 9.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit Roc PF08477.13 GAN10120.1 - 0.006 16.8 0.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAN10120.1 - 0.048 14.2 0.2 0.16 12.5 0.2 2.0 1 1 0 1 1 1 0 ABC transporter GBP PF02263.19 GAN10120.1 - 0.05 12.9 0.0 0.6 9.3 0.0 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Ras PF00071.22 GAN10120.1 - 0.098 12.3 0.0 0.41 10.2 0.0 1.9 1 1 0 1 1 1 0 Ras family Flavoprotein PF02441.19 GAN10121.1 - 7.2e-49 165.6 0.9 1.5e-48 164.5 0.3 1.8 2 0 0 2 2 2 1 Flavoprotein SH3_1 PF00018.28 GAN10121.1 - 4.9e-10 38.9 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN10121.1 - 1.6e-09 37.4 0.1 3.4e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN10121.1 - 4.3e-07 29.5 0.0 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_4 PF12763.7 GAN10121.1 - 0.00044 20.1 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GAN10121.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 EF hand IPP-2 PF04979.14 GAN10122.1 - 1.1e-18 68.2 10.6 1.5e-18 67.8 10.6 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Nucleo_P87 PF07267.11 GAN10122.1 - 0.51 9.1 3.6 0.51 9.1 3.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Prenyltrans PF00432.21 GAN10123.1 - 3e-40 135.6 14.1 4.5e-09 35.9 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAN10123.1 - 0.00052 19.2 0.1 1.7 7.6 0.0 3.2 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAN10123.1 - 0.0032 16.6 0.0 2.4 7.2 0.0 2.7 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain CAF1C_H4-bd PF12265.8 GAN10124.1 - 1.6e-29 101.9 0.6 3.8e-29 100.8 0.6 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAN10124.1 - 4.6e-23 81.1 13.0 1.7e-05 25.5 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 GAN10124.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Ecl1 PF12855.7 GAN10125.1 - 4.6e-12 47.5 15.0 6e-12 47.1 15.0 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 GAN10125.1 - 0.0034 17.4 0.3 0.0071 16.4 0.3 1.5 1 0 0 1 1 1 1 MYND finger Mem_trans PF03547.18 GAN10126.1 - 1.7e-51 174.9 2.1 2.1e-51 174.5 2.1 1.1 1 0 0 1 1 1 1 Membrane transport protein EAP30 PF04157.16 GAN10127.1 - 7.6e-70 234.9 0.1 8.6e-70 234.7 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.12 GAN10127.1 - 0.00012 22.1 1.2 0.0086 16.0 0.6 2.3 2 0 0 2 2 2 2 Bacteriophage Mu Gam like protein APG6 PF04111.12 GAN10128.1 - 2.4e-77 258.9 0.0 5.2e-77 257.8 0.0 1.6 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 GAN10128.1 - 6.4e-32 110.9 23.8 1.4e-31 109.7 23.8 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region GOLGA2L5 PF15070.6 GAN10128.1 - 0.0028 16.4 16.5 0.0039 15.9 16.5 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 BH3 PF15285.6 GAN10128.1 - 0.014 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting SYCE1 PF15233.6 GAN10128.1 - 0.12 12.5 17.6 0.17 12.0 16.8 1.6 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 FapA PF03961.13 GAN10128.1 - 0.21 10.2 6.6 0.29 9.7 6.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Flagellin_N PF00669.20 GAN10128.1 - 1.1 9.3 4.9 0.41 10.7 2.0 1.7 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4140 PF13600.6 GAN10128.1 - 2.2 8.8 5.3 7.5 7.1 5.3 1.9 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Sua5_yciO_yrdC PF01300.18 GAN10129.1 - 3.8e-54 182.9 0.0 5.7e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 GAN10129.1 - 3.1e-33 115.2 0.1 5.8e-33 114.3 0.0 1.5 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding COPIIcoated_ERV PF07970.12 GAN10130.1 - 9.8e-75 251.2 1.3 1.3e-74 250.8 1.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAN10130.1 - 3.8e-29 100.9 0.7 9e-29 99.7 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Enolase_C PF00113.22 GAN10131.1 - 2e-154 513.2 0.1 2.6e-154 512.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAN10131.1 - 8e-56 187.8 0.1 1.6e-55 186.8 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAN10131.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAN10131.1 - 0.0018 17.5 0.1 0.0036 16.5 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF4327 PF14217.6 GAN10131.1 - 0.024 14.7 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) RNase_PH PF01138.21 GAN10132.1 - 7.6e-21 75.0 0.0 1.1e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAN10132.1 - 2.3e-12 46.8 0.0 4.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF4598 PF15370.6 GAN10133.1 - 2.1e-21 76.5 1.6 2.1e-21 76.5 1.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) WSS_VP PF12175.8 GAN10133.1 - 0.071 12.6 0.8 0.1 12.0 0.8 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP DDE_3 PF13358.6 GAN10135.1 - 0.00038 20.2 0.1 0.00099 18.9 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Nuc_deoxyrib_tr PF05014.15 GAN10136.1 - 0.086 12.9 0.0 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase SRCR_2 PF15494.6 GAN10137.1 - 0.011 16.3 0.3 0.016 15.8 0.3 1.2 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Arf PF00025.21 GAN10139.1 - 2.1e-45 154.3 0.2 2.3e-45 154.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAN10139.1 - 2.4e-21 76.0 0.0 2.9e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN10139.1 - 9.1e-18 64.6 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAN10139.1 - 6.3e-12 45.3 0.0 7.1e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN10139.1 - 4.4e-09 36.4 0.0 6.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAN10139.1 - 5.1e-09 35.8 0.0 5.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAN10139.1 - 4.1e-08 32.8 0.9 5e-06 25.9 0.0 2.5 1 1 2 3 3 3 2 G-protein alpha subunit GTP_EFTU PF00009.27 GAN10139.1 - 0.00011 21.7 0.1 0.0025 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAN10139.1 - 0.0066 16.5 0.1 0.63 10.1 0.2 2.2 1 1 1 2 2 2 1 Dynamin family cobW PF02492.19 GAN10139.1 - 0.02 14.5 0.1 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 GAN10139.1 - 0.052 13.1 1.7 0.12 11.9 0.1 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 GAN10139.1 - 0.074 13.3 0.1 1.6 9.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAN10139.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CAP PF00188.26 GAN10140.1 - 1.1e-20 74.8 8.6 5.8e-20 72.4 8.6 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_M9_N PF08453.10 GAN10140.1 - 0.078 12.7 0.6 9.4 5.9 0.0 2.2 1 1 1 2 2 2 0 Peptidase family M9 N-terminal Rap_GAP PF02145.15 GAN10141.1 - 6.3e-23 81.3 0.0 1.5e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Nup192 PF11894.8 GAN10141.1 - 0.042 11.0 0.1 0.09 9.9 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 F-box-like PF12937.7 GAN10142.1 - 1.2e-06 28.3 0.2 3.2e-06 26.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN10142.1 - 5.2e-05 23.0 0.1 5.2e-05 23.0 0.1 2.1 3 0 0 3 3 3 1 F-box domain LRR_2 PF07723.13 GAN10142.1 - 0.0096 16.6 1.5 0.36 11.6 0.0 3.4 2 0 0 2 2 2 1 Leucine Rich Repeat DUF588 PF04535.12 GAN10142.1 - 0.025 14.4 0.0 2.3 8.0 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF588) LRR_6 PF13516.6 GAN10142.1 - 0.61 10.3 4.6 27 5.2 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 GAN10142.1 - 3.4 8.2 6.4 26 5.4 0.0 4.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) HSF_DNA-bind PF00447.17 GAN10143.1 - 6.3e-33 113.3 1.0 6.3e-33 113.3 1.0 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding DUF1804 PF08822.11 GAN10143.1 - 0.12 12.3 1.9 0.47 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) PI_PP_I PF18363.1 GAN10143.1 - 0.31 11.3 6.6 0.13 12.5 0.7 2.6 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain ANAPC_CDC26 PF10471.9 GAN10143.1 - 0.68 10.8 30.4 0.38 11.6 5.9 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Androgen_recep PF02166.16 GAN10143.1 - 1.3 7.8 30.2 0.63 8.8 10.3 2.6 2 0 0 2 2 2 0 Androgen receptor BRF1 PF07741.13 GAN10143.1 - 1.8 9.0 8.2 9.1 6.7 0.9 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1664 PF07889.12 GAN10143.1 - 2.5 8.2 8.1 2.4 8.2 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) tRNA_synt_1c_R2 PF04557.15 GAN10143.1 - 3.4 8.7 7.9 8.2 7.4 0.9 3.0 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 F-box-like PF12937.7 GAN10145.1 - 3.3e-05 23.7 1.1 7.6e-05 22.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GAN10145.1 - 0.00011 22.5 0.0 0.39 11.2 0.0 4.1 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAN10145.1 - 0.0004 20.2 6.4 4.1 7.7 0.1 5.1 5 0 0 5 5 5 2 Leucine Rich repeat NPM1-C PF16276.5 GAN10145.1 - 0.16 12.0 0.9 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain LRR_1 PF00560.33 GAN10145.1 - 0.29 11.8 4.9 1.5e+02 3.6 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Proteasome PF00227.26 GAN10146.1 - 1.3e-36 125.9 0.1 2.4e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit Snurportin1 PF11538.8 GAN10149.1 - 0.00012 22.2 7.1 0.00034 20.7 7.1 1.8 1 0 0 1 1 1 1 Snurportin1 DUF572 PF04502.13 GAN10149.1 - 0.0017 18.0 11.6 0.0022 17.7 11.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) FapA PF03961.13 GAN10149.1 - 0.11 11.0 8.5 0.15 10.7 8.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Merozoite_SPAM PF07133.11 GAN10149.1 - 0.5 10.3 18.6 0.89 9.5 18.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) IBB PF01749.20 GAN10149.1 - 1.4 9.4 15.3 6 7.4 15.3 2.0 1 1 0 1 1 1 0 Importin beta binding domain Elf1 PF05129.13 GAN10150.1 - 7.3e-29 99.6 5.4 7.3e-29 99.6 5.4 1.4 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.19 GAN10150.1 - 0.27 11.3 1.4 0.55 10.3 1.4 1.5 1 1 0 1 1 1 0 Ribosomal L37ae protein family zf-Sec23_Sec24 PF04810.15 GAN10150.1 - 0.52 10.4 8.8 1.6 8.8 1.4 2.7 1 1 2 3 3 3 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 GAN10150.1 - 1.4 8.4 8.6 4.6 6.7 8.5 1.9 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Y_phosphatase3 PF13350.6 GAN10151.1 - 2.3e-53 181.5 0.0 3.6e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 GAN10151.1 - 4.3e-09 36.0 0.0 2.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN10151.1 - 1.2e-07 31.6 0.0 5.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN10151.1 - 6.8e-07 30.1 0.0 1.5e-06 28.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAN10151.1 - 0.00063 19.6 0.0 0.23 11.2 0.0 2.6 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Y_phosphatase PF00102.27 GAN10151.1 - 0.00069 19.3 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Peptidase_S9 PF00326.21 GAN10151.1 - 0.00077 19.0 0.0 0.0016 17.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 GAN10151.1 - 0.0016 18.2 0.0 0.004 16.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Y_phosphatase2 PF03162.13 GAN10151.1 - 0.0057 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAN10151.1 - 0.021 14.7 0.0 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Esterase PF00756.20 GAN10151.1 - 0.067 12.8 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Putative esterase DnaJ_C PF01556.18 GAN10152.1 - 1e-44 152.2 1.2 1.4e-44 151.7 1.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAN10152.1 - 1.9e-26 92.0 2.9 3.3e-26 91.2 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAN10152.1 - 1.4e-11 44.6 22.8 2.8e-11 43.6 22.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAN10152.1 - 0.0052 16.7 18.4 0.029 14.3 4.5 2.6 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAN10152.1 - 0.04 13.9 12.9 0.21 11.6 4.5 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_C74 PF12387.8 GAN10152.1 - 0.082 12.4 0.9 0.14 11.6 0.9 1.3 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Brix PF04427.18 GAN10153.1 - 8.1e-34 117.4 0.2 1.1e-33 117.0 0.2 1.2 1 0 0 1 1 1 1 Brix domain adh_short PF00106.25 GAN10154.1 - 1.7e-29 102.7 0.0 2.2e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN10154.1 - 9.6e-24 84.2 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TPR_1 PF00515.28 GAN10155.1 - 1.3e-17 62.8 7.8 0.00094 18.9 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAN10155.1 - 5.4e-16 58.0 6.3 0.00052 19.6 0.2 4.5 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.17 GAN10155.1 - 6e-14 51.0 12.1 0.00094 19.1 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10155.1 - 1.2e-11 45.0 5.4 7.4e-06 26.4 0.4 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10155.1 - 7.7e-11 41.3 3.6 0.17 12.2 0.1 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10155.1 - 1.6e-10 40.6 5.1 0.0066 16.7 0.1 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN10155.1 - 3.1e-09 36.9 13.5 0.088 13.7 1.8 5.8 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10155.1 - 7.3e-09 36.1 6.7 9.2e-05 23.0 0.1 4.2 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.6 GAN10155.1 - 8.5e-08 32.4 2.6 0.0097 16.2 0.1 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAN10155.1 - 1.4e-06 27.9 6.6 0.32 11.1 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN10155.1 - 2.9e-06 27.5 9.4 0.032 14.5 0.9 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAN10155.1 - 6.1e-05 23.1 7.9 0.17 12.1 0.2 3.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAN10155.1 - 0.0095 16.5 0.1 0.044 14.4 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1641 PF07849.11 GAN10155.1 - 0.14 12.0 0.3 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TPR_6 PF13174.6 GAN10155.1 - 0.21 12.3 3.3 9.9 7.1 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN10155.1 - 0.54 10.5 6.5 0.2 11.9 1.5 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ERCC4 PF02732.15 GAN10156.1 - 5.3e-14 52.7 0.0 5.3e-14 52.7 0.0 2.5 3 0 0 3 3 3 1 ERCC4 domain Nop53 PF07767.11 GAN10156.1 - 0.0064 15.9 13.4 0.012 15.0 13.4 1.4 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CUE PF02845.16 GAN10156.1 - 0.017 14.8 0.0 0.053 13.2 0.0 1.9 1 0 0 1 1 1 0 CUE domain DUF4460 PF14687.6 GAN10156.1 - 0.063 13.3 1.1 0.86 9.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4460) adh_short PF00106.25 GAN10157.1 - 7.1e-26 90.9 0.0 1e-20 74.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAN10157.1 - 8.7e-12 45.1 0.0 6.9e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN10157.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN10157.1 - 0.0019 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Calici_MSP PF05752.11 GAN10157.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein Glyco_transf_8 PF01501.20 GAN10158.1 - 1.7e-20 73.6 0.1 2.9e-18 66.4 0.1 2.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAN10158.1 - 0.00089 18.7 0.0 0.00089 18.7 0.0 2.5 3 0 0 3 3 3 1 Mannosyltransferase putative PTH2 PF01981.16 GAN10159.1 - 6.6e-47 158.6 0.1 1.6e-46 157.4 0.0 1.6 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 HTH_19 PF12844.7 GAN10159.1 - 0.06 13.4 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain OPT PF03169.15 GAN10161.1 - 4.2e-91 306.4 38.8 4.9e-91 306.2 38.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 GAN10161.1 - 0.0023 18.2 0.3 0.008 16.4 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3093) DUF4730 PF15873.5 GAN10161.1 - 0.16 12.2 1.4 13 6.1 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) Halogen_Hydrol PF10112.9 GAN10161.1 - 0.69 9.9 4.6 0.48 10.4 0.6 2.6 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4191 PF13829.6 GAN10161.1 - 0.72 9.2 3.5 2.3 7.5 3.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Ssu72 PF04722.13 GAN10162.1 - 6.5e-86 286.8 0.0 7.3e-86 286.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein zf-RING_7 PF02591.15 GAN10162.1 - 0.17 12.1 0.2 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain PITH PF06201.13 GAN10163.1 - 1.2e-37 129.5 7.8 1.2e-37 129.5 7.8 1.5 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 GAN10163.1 - 7.1e-30 103.0 1.8 2.2e-29 101.5 1.8 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAN10163.1 - 2.4e-05 24.5 1.6 5.5e-05 23.4 0.2 2.2 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 GAN10163.1 - 0.00021 20.7 0.3 0.00045 19.7 0.3 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAN10163.1 - 0.0031 17.9 2.9 0.0069 16.8 1.5 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAN10163.1 - 0.096 12.5 0.4 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Thioredoxin UbiA PF01040.18 GAN10164.1 - 7.6e-58 195.8 17.8 9.7e-58 195.4 17.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Mo-nitro_C PF06967.11 GAN10164.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Mo-dependent nitrogenase C-terminus Pkinase PF00069.25 GAN10165.1 - 3.5e-72 242.9 0.0 4.3e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10165.1 - 2.5e-34 118.7 0.0 3.5e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN10165.1 - 5.4e-07 29.2 0.0 7.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN10165.1 - 3.3e-05 22.8 0.0 6.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAN10165.1 - 3.3e-05 23.3 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAN10165.1 - 0.0027 17.2 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 GAN10165.1 - 0.0073 16.3 0.1 0.016 15.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Phage_connect_1 PF05135.13 GAN10165.1 - 0.19 12.3 0.9 0.76 10.3 0.3 2.3 2 1 0 2 2 2 0 Phage gp6-like head-tail connector protein ADH_N PF08240.12 GAN10166.1 - 0.00016 21.5 0.0 0.0023 17.8 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAN10167.1 - 9.9e-06 26.6 0.1 1e-05 26.6 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAN10167.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RPAP3_C PF13877.6 GAN10168.1 - 2.3e-23 82.5 0.0 5.1e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 GAN10168.1 - 1e-18 66.3 0.1 1.6e-06 27.7 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10168.1 - 3.4e-16 58.0 0.1 0.00034 20.5 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10168.1 - 8.7e-12 44.3 0.0 0.0026 17.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN10168.1 - 4.3e-10 39.1 0.0 6.1e-06 25.8 0.0 3.2 2 1 1 3 3 3 3 TPR repeat TPR_9 PF13371.6 GAN10168.1 - 3.9e-06 26.9 0.0 9.3e-06 25.7 0.0 1.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10168.1 - 0.00038 21.0 0.0 0.012 16.2 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10168.1 - 0.0016 18.9 0.0 1.6 9.3 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN10168.1 - 0.0062 16.8 0.4 0.6 10.4 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10168.1 - 0.0079 16.5 0.0 2.7 8.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAN10168.1 - 0.013 15.5 0.0 3.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GAN10168.1 - 0.024 15.4 0.0 5.8 8.0 0.0 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat Trehalase PF01204.18 GAN10169.1 - 7.2e-179 595.9 4.3 1.5e-178 594.8 4.3 1.6 1 0 0 1 1 1 1 Trehalase NRDE-2 PF08424.10 GAN10169.1 - 3.1e-94 315.7 4.3 3.1e-94 315.7 4.3 3.4 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference Trehalase_Ca-bi PF07492.11 GAN10169.1 - 7.9e-15 54.3 1.4 1.7e-14 53.2 1.4 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain TPR_14 PF13428.6 GAN10169.1 - 3.3e-08 33.7 0.2 2.9 9.0 0.0 7.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10169.1 - 0.00064 20.2 1.2 0.82 10.2 0.1 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN10169.1 - 0.0018 18.5 2.8 0.0034 17.6 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10169.1 - 0.013 15.5 0.7 11 6.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAN10169.1 - 0.025 13.8 12.1 0.4 9.8 0.1 5.2 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10169.1 - 0.036 14.5 1.6 33 5.2 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAN10169.1 - 0.059 13.4 9.0 1.3 9.0 0.3 4.8 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 TPR_MalT PF17874.1 GAN10169.1 - 1.7 8.0 4.0 11 5.3 0.2 2.7 2 0 0 2 2 2 0 MalT-like TPR region HMGL-like PF00682.19 GAN10171.1 - 1.3e-57 195.4 0.0 1.6e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 HMGL-like F1F0-ATPsyn_F PF10791.9 GAN10172.1 - 8.5e-34 115.9 0.1 9.4e-34 115.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 GAN10172.1 - 1.2e-05 25.6 0.0 1.5e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f RTC4 PF14474.6 GAN10173.1 - 8.5e-25 87.3 0.0 2e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain Fer2_3 PF13085.6 GAN10175.1 - 1.6e-33 114.9 0.0 2.7e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAN10175.1 - 2e-09 37.8 8.1 2e-09 37.8 8.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAN10175.1 - 2.5e-07 31.0 12.2 7.4e-07 29.5 9.7 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAN10175.1 - 2.3e-06 27.6 4.3 2.3e-06 27.6 4.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAN10175.1 - 0.0013 18.6 2.7 0.0054 16.7 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 GAN10175.1 - 0.0021 18.6 6.7 0.0021 18.6 6.7 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.8 GAN10175.1 - 0.042 14.4 1.1 0.053 14.1 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 GAN10175.1 - 0.38 11.0 14.3 0.093 12.9 8.4 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 GAN10175.1 - 0.54 10.5 5.4 0.88 9.8 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain DUF4210 PF13915.6 GAN10176.1 - 3.5e-29 101.2 1.0 3.1e-28 98.1 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 GAN10176.1 - 2.3e-20 72.5 0.1 5.4e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis Arf PF00025.21 GAN10177.1 - 0.0076 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Mito_carr PF00153.27 GAN10178.1 - 2.6e-64 213.2 4.9 1.6e-22 79.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN10178.1 - 6.7e-05 22.2 0.1 0.002 17.4 0.0 2.6 2 1 0 2 2 2 1 Gammaproteobacterial serine protease Fe-ADH PF00465.19 GAN10178.1 - 0.11 11.3 0.5 0.96 8.2 0.0 2.0 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Ribosomal_S8e PF01201.22 GAN10179.1 - 1.5e-51 174.1 0.6 2.8e-51 173.3 0.6 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Tnp_22_trimer PF17489.2 GAN10179.1 - 0.28 11.2 0.2 0.28 11.2 0.2 2.7 3 0 0 3 3 3 0 L1 transposable element trimerization domain TPR_1 PF00515.28 GAN10180.1 - 2.2e-09 36.7 6.6 0.0071 16.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10180.1 - 1.2e-05 25.0 8.8 0.071 13.3 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF3856 PF12968.7 GAN10180.1 - 6.6e-05 23.0 0.4 0.0002 21.5 0.4 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) UBA PF00627.31 GAN10180.1 - 0.001 18.9 0.1 0.001 18.9 0.1 2.8 3 0 0 3 3 3 1 UBA/TS-N domain TPR_12 PF13424.6 GAN10180.1 - 0.0011 19.2 1.2 0.064 13.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Syntaxin-18_N PF10496.9 GAN10180.1 - 0.022 15.0 0.2 0.022 15.0 0.2 3.5 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus TPR_8 PF13181.6 GAN10180.1 - 0.027 14.7 8.3 2.8 8.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10180.1 - 0.029 15.0 0.3 6.1 7.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 GAN10180.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain TPR_11 PF13414.6 GAN10180.1 - 0.17 11.6 1.3 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 GAN10180.1 - 0.32 11.9 1.5 31 5.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CHCC PF10276.9 GAN10181.1 - 1.6e-17 63.3 3.1 2.6e-17 62.5 3.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain Bromodomain PF00439.25 GAN10183.1 - 2.8e-121 395.9 9.0 1.3e-20 73.3 0.0 6.9 6 0 0 6 6 6 6 Bromodomain Peptidase_M1 PF01433.20 GAN10183.1 - 2e-06 27.6 0.6 0.00061 19.4 0.0 2.7 2 0 0 2 2 2 2 Peptidase family M1 domain F1F0-ATPsyn_F PF10791.9 GAN10183.1 - 0.15 12.6 0.4 0.73 10.3 0.4 2.2 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi CH PF00307.31 GAN10185.1 - 0.00029 21.0 0.2 0.00082 19.5 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain Lipase_GDSL PF00657.22 GAN10186.1 - 7.5e-12 45.6 0.3 1e-11 45.2 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN10186.1 - 2.7e-08 34.4 0.0 2e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PLDc_2 PF13091.6 GAN10187.1 - 5.9e-14 52.1 0.0 5.6e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAN10187.1 - 0.006 16.7 2.9 1.1 9.6 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif RhoGEF PF00621.20 GAN10188.1 - 6e-37 127.6 3.5 6e-37 127.6 3.5 1.9 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.11 GAN10188.1 - 1.5e-26 92.5 1.0 7.6e-26 90.2 0.3 2.5 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.24 GAN10188.1 - 2.3e-12 46.7 0.0 6.3e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 PB1 domain PH_10 PF15411.6 GAN10188.1 - 4e-11 43.2 2.6 7.1e-11 42.4 0.6 2.3 1 1 1 2 2 2 1 Pleckstrin homology domain CRAL_TRIO PF00650.20 GAN10189.1 - 2.2e-12 47.0 0.1 4.8e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAN10189.1 - 0.0045 17.1 0.3 0.011 15.9 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1474 PF07342.11 GAN10189.1 - 0.077 13.5 0.7 17 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) DUF1296 PF06972.11 GAN10189.1 - 0.14 12.4 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) HEAT PF02985.22 GAN10190.1 - 3.9e-17 60.9 5.1 0.0047 17.1 0.3 7.5 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 GAN10190.1 - 9.4e-05 22.7 1.1 0.93 9.9 0.0 5.5 4 2 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 GAN10190.1 - 0.04 14.0 6.6 0.42 10.7 0.0 4.9 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAN10190.1 - 0.92 10.1 2.6 36 5.0 0.0 3.8 3 1 0 3 3 3 0 HEAT-like repeat GTP_EFTU PF00009.27 GAN10191.1 - 4.7e-58 196.0 0.3 6.8e-58 195.4 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAN10191.1 - 3.2e-30 104.7 1.4 3.6e-30 104.6 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAN10191.1 - 3e-17 62.8 3.6 7.5e-17 61.5 3.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAN10191.1 - 2.3e-05 24.4 0.1 4.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 GAN10191.1 - 0.003 17.2 0.8 0.0041 16.7 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAN10191.1 - 0.0087 16.0 0.2 0.034 14.0 0.1 1.9 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 GAN10191.1 - 0.013 15.2 0.3 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2917 PF11142.8 GAN10191.1 - 0.1 12.0 0.0 4.6 6.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2917) Alba PF01918.21 GAN10191.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Alba zf-Tim10_DDP PF02953.15 GAN10193.1 - 2.6e-26 91.1 2.4 3e-26 90.8 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Erf4 PF10256.9 GAN10193.1 - 0.056 13.5 0.0 0.086 13.0 0.0 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Sulfotransfer_4 PF17784.1 GAN10194.1 - 6.9e-55 186.2 0.0 8.4e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAN10194.1 - 7.2e-06 26.5 0.5 0.00047 20.6 0.2 2.6 1 1 1 2 2 2 2 Sulfotransferase family GSCFA PF08885.11 GAN10194.1 - 0.082 12.5 0.0 6.6 6.3 0.0 2.3 1 1 1 2 2 2 0 GSCFA family Ras PF00071.22 GAN10195.1 - 5.1e-28 97.7 0.4 6.2e-28 97.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN10195.1 - 0.0017 18.6 0.1 0.0032 17.7 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase UCH PF00443.29 GAN10196.1 - 2.6e-45 154.9 2.4 5e-45 154.0 2.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 GAN10196.1 - 6.1e-34 117.4 0.2 3.2e-33 115.1 0.0 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 GAN10196.1 - 1.7e-29 103.0 0.7 6.9e-29 101.0 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 GAN10196.1 - 2.3e-26 93.1 5.1 3e-25 89.5 2.5 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GAN10196.1 - 0.00017 21.7 1.7 0.00051 20.2 1.7 1.9 1 0 0 1 1 1 1 MATH domain Asparaginase PF00710.20 GAN10197.1 - 0.027 14.0 0.1 0.042 13.4 0.1 1.3 1 1 0 1 1 1 0 Asparaginase, N-terminal Retrotrans_gag PF03732.17 GAN10198.1 - 5e-15 55.5 0.0 7.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 GAN10198.1 - 0.0014 18.7 4.6 0.0014 18.7 4.6 1.9 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_6 PF15288.6 GAN10198.1 - 0.15 11.9 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle PHD PF00628.29 GAN10201.1 - 2.8e-11 43.1 12.7 4.4e-11 42.5 12.7 1.3 1 0 0 1 1 1 1 PHD-finger Terminase_GpA PF05876.12 GAN10201.1 - 0.00065 18.4 2.8 0.00065 18.4 2.8 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) PHD_2 PF13831.6 GAN10201.1 - 0.00094 18.7 5.6 0.0017 17.9 5.6 1.4 1 0 0 1 1 1 1 PHD-finger PolC_DP2 PF03833.13 GAN10201.1 - 0.025 12.5 5.2 0.025 12.5 5.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2197 PF09963.9 GAN10201.1 - 0.25 11.6 6.2 0.6 10.4 6.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-CW PF07496.15 GAN10201.1 - 2.2 8.4 10.4 0.098 12.7 4.8 1.8 2 0 0 2 2 2 0 CW-type Zinc Finger SET PF00856.28 GAN10202.1 - 6.8e-06 26.6 0.1 6.8e-06 26.6 0.1 3.4 2 2 0 2 2 2 1 SET domain Cytadhesin_P30 PF07271.11 GAN10202.1 - 0.025 14.1 0.3 0.05 13.2 0.3 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 ArgJ PF01960.18 GAN10203.1 - 1.9e-149 497.5 1.9 2.2e-149 497.3 1.9 1.0 1 0 0 1 1 1 1 ArgJ family DNA_pol_B PF00136.21 GAN10204.1 - 4.9e-150 500.2 2.0 9.4e-150 499.3 2.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAN10204.1 - 1.5e-83 280.7 0.0 2.2e-82 276.9 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAN10204.1 - 1.4e-17 63.9 7.6 2.9e-17 62.9 7.6 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 GAN10204.1 - 3.5e-05 22.9 1.4 0.0037 16.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 GAN10204.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAN10204.1 - 0.027 14.5 0.1 0.11 12.5 0.1 2.1 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 GAN10204.1 - 0.094 12.4 0.8 0.6 9.8 0.1 2.3 2 0 0 2 2 2 0 3'-5' exonuclease C1_1 PF00130.22 GAN10204.1 - 0.11 12.4 5.7 0.38 10.7 5.7 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ACC PF17848.1 GAN10204.1 - 0.6 10.2 2.8 1.1 9.4 0.8 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 GAN10204.1 - 1 9.5 4.4 2.6 8.1 4.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon DUF5040 PF16443.5 GAN10205.1 - 0.04 13.3 0.2 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) DUF1492 PF07374.11 GAN10205.1 - 0.055 13.6 0.5 0.078 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) DUF3853 PF12964.7 GAN10205.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Ribosomal_L1 PF00687.21 GAN10207.1 - 4.8e-36 124.4 1.6 5.7e-36 124.2 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L5_C PF00673.21 GAN10208.1 - 1.2e-27 95.9 0.0 1.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAN10208.1 - 6.8e-12 45.5 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 LCAT PF02450.15 GAN10209.1 - 1.3e-85 287.9 0.1 5.9e-85 285.8 0.1 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 GAN10209.1 - 0.003 17.1 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 2) Kinesin PF00225.23 GAN10210.1 - 0.00033 19.7 0.0 0.00046 19.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.23 GAN10211.1 - 4e-78 262.7 1.5 4e-78 262.7 1.5 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAN10211.1 - 7.8e-07 29.1 0.1 4.6e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Siah-Interact_N PF09032.11 GAN10211.1 - 0.086 13.2 5.7 0.42 11.0 0.9 3.0 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF641 PF04859.12 GAN10211.1 - 0.2 12.0 6.5 0.14 12.5 1.1 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) THOC7 PF05615.13 GAN10211.1 - 4.2 7.7 10.7 1.2 9.4 6.7 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 AidB_N PF18158.1 GAN10214.1 - 4.3e-25 88.5 0.0 7.6e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAN10214.1 - 1.1e-20 74.4 0.6 2.1e-20 73.5 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAN10214.1 - 4.8e-14 52.3 0.1 8.4e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAN10214.1 - 1.9e-07 31.4 0.0 4.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Redoxin PF08534.10 GAN10215.1 - 8.9e-35 119.6 0.0 1.6e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAN10215.1 - 2.4e-14 53.3 0.0 9.3e-14 51.4 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family O-FucT PF10250.9 GAN10215.1 - 7.4e-08 32.5 0.4 4.4e-06 26.6 0.4 3.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase VAR1 PF05316.12 GAN10216.1 - 0.22 10.5 4.7 0.45 9.5 4.7 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) FUR PF01475.19 GAN10217.1 - 0.0095 16.1 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Ferric uptake regulator family AAA_assoc PF14363.6 GAN10217.1 - 0.12 12.7 0.1 0.49 10.8 0.0 2.1 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA zf-RVT PF13966.6 GAN10218.1 - 1.9e-05 25.3 0.5 3.7e-05 24.3 0.5 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Ribosomal_L37ae PF01780.19 GAN10219.1 - 0.046 13.8 0.0 0.28 11.3 0.0 2.3 1 1 1 2 2 2 0 Ribosomal L37ae protein family Gasdermin PF04598.12 GAN10219.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Gasdermin pore forming domain NDUF_B7 PF05676.13 GAN10219.1 - 0.39 10.5 4.2 0.17 11.6 0.5 2.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) HTH_24 PF13412.6 GAN10220.1 - 0.00026 20.5 0.4 0.001 18.6 0.1 2.1 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 GAN10220.1 - 0.00051 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 GAN10220.1 - 0.0026 17.6 0.1 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 GAN10220.1 - 0.003 17.3 0.1 0.0065 16.2 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_32 PF13565.6 GAN10220.1 - 0.0036 17.9 0.0 0.0086 16.7 0.0 1.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 GAN10220.1 - 0.004 16.9 0.0 0.009 15.8 0.0 1.6 2 0 0 2 2 1 1 Homeodomain-like domain Mga PF05043.13 GAN10220.1 - 0.0047 17.5 0.2 0.0097 16.5 0.2 1.5 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_28 PF13518.6 GAN10220.1 - 0.0059 16.7 0.0 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 GAN10220.1 - 0.0064 16.1 0.2 0.14 11.9 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_1 PF00126.27 GAN10220.1 - 0.015 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF134 PF02001.16 GAN10220.1 - 0.017 15.7 0.2 0.046 14.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF134 HTH_AraC PF00165.23 GAN10220.1 - 0.032 14.3 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Stork_head PF10264.9 GAN10220.1 - 0.037 14.2 0.1 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain HTH_Tnp_ISL3 PF13542.6 GAN10220.1 - 0.054 12.9 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 GAN10220.1 - 0.061 13.3 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_DeoR PF08220.12 GAN10220.1 - 0.066 13.0 0.1 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 GAN10220.1 - 0.12 12.4 0.0 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain SRR1 PF07985.12 GAN10221.1 - 0.12 12.5 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 SRR1 Acetyltransf_1 PF00583.25 GAN10222.1 - 4e-12 46.4 0.0 5.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN10222.1 - 2.5e-08 33.9 0.0 5.5e-08 32.8 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN10222.1 - 4.1e-08 33.5 0.1 1.3e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN10222.1 - 6.5e-07 29.2 0.0 4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 GAN10222.1 - 3.7e-05 23.8 0.1 7.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAN10222.1 - 0.0022 18.1 0.1 0.0031 17.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_4C PF11975.8 GAN10222.1 - 0.016 15.3 0.2 0.021 14.9 0.2 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain LepB_GAP_N PF18172.1 GAN10222.1 - 0.18 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain Pkinase PF00069.25 GAN10223.1 - 1.2e-33 116.6 0.0 1.1e-18 67.6 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10223.1 - 4.3e-11 42.6 0.3 0.00015 21.2 0.2 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase MFS_1 PF07690.16 GAN10224.1 - 9.2e-27 93.9 42.3 9.2e-27 93.9 42.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN10224.1 - 2.4e-12 46.5 6.7 2.4e-12 46.5 6.7 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAN10224.1 - 3.1e-06 25.9 29.0 6.7e-06 24.8 29.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5362 PF17319.2 GAN10224.1 - 5.9 6.8 8.8 7.4 6.5 0.0 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5362) RINGv PF12906.7 GAN10225.1 - 2.3e-09 37.2 5.9 3.9e-09 36.5 5.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 GAN10225.1 - 0.028 14.2 6.9 0.099 12.5 6.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GAN10225.1 - 0.17 12.2 7.7 0.36 11.2 7.7 1.6 1 1 0 1 1 1 0 Ring finger domain zf-AD PF07776.15 GAN10225.1 - 0.2 11.9 4.8 0.22 11.8 3.8 1.6 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) UPF0014 PF03649.13 GAN10226.1 - 2.7e-43 148.1 13.9 3.1e-43 147.9 13.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.22 GAN10226.1 - 0.0016 18.2 9.2 0.002 17.9 9.2 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OATP PF03137.20 GAN10226.1 - 0.033 12.5 0.5 0.05 11.9 0.5 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PHD PF00628.29 GAN10228.1 - 1.9e-06 27.6 9.1 4.2e-06 26.5 9.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAN10228.1 - 0.064 12.8 8.6 0.1 12.2 8.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 GAN10228.1 - 0.57 10.2 6.1 1.3 9.1 6.1 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger eIF3m_C_helix PF18005.1 GAN10229.1 - 3.3e-12 45.9 0.5 7.3e-12 44.8 0.5 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 GAN10229.1 - 4.2e-11 43.3 2.0 4.9e-11 43.1 0.3 2.1 3 0 0 3 3 3 1 PCI domain ING PF12998.7 GAN10230.1 - 4.1e-11 43.3 6.0 4.1e-11 43.3 6.0 2.1 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAN10230.1 - 2.1e-06 27.5 8.2 4e-06 26.6 8.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAN10230.1 - 0.0024 17.4 2.8 0.0056 16.2 2.8 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAN10230.1 - 0.043 14.1 0.3 0.11 12.8 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAN10230.1 - 0.053 13.7 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain DNA_pol_phi PF04931.13 GAN10230.1 - 0.12 10.5 11.3 0.1 10.7 8.6 2.0 2 0 0 2 2 2 0 DNA polymerase phi CDC45 PF02724.14 GAN10230.1 - 0.13 10.5 4.2 0.17 10.1 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAN10230.1 - 1.7 7.1 5.5 2.2 6.8 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 GAN10230.1 - 10 5.3 7.4 2.6 7.2 4.1 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FHA PF00498.26 GAN10231.1 - 3e-18 65.9 0.0 5.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAN10231.1 - 1.4e-06 28.5 0.0 1.1e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PSP1 PF04468.12 GAN10233.1 - 4.1e-33 113.5 2.7 4.1e-33 113.5 2.7 2.9 3 0 0 3 3 3 1 PSP1 C-terminal conserved region DUF702 PF05142.12 GAN10233.1 - 0.67 10.4 10.7 1.9 8.9 2.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF702) Draxin PF15550.6 GAN10233.1 - 10 5.9 13.6 24 4.7 13.6 1.6 1 0 0 1 1 1 0 Draxin GATA PF00320.27 GAN10234.1 - 4e-17 61.5 3.5 8.5e-17 60.5 3.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 GAN10234.1 - 7.1e-14 51.3 0.9 1.7e-13 50.1 0.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RskA PF10099.9 GAN10234.1 - 0.015 15.6 1.0 0.015 15.6 1.0 3.6 3 0 0 3 3 3 0 Anti-sigma-K factor rskA TF_Zn_Ribbon PF08271.12 GAN10234.1 - 0.24 11.0 0.6 0.47 10.0 0.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding GET2 PF08690.10 GAN10236.1 - 0.41 10.3 1.5 0.51 10.0 1.5 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DPPIV_N PF00930.21 GAN10237.1 - 3.5e-97 325.4 9.2 5.6e-97 324.7 9.2 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAN10237.1 - 9.5e-54 182.1 1.4 1.9e-53 181.1 1.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAN10237.1 - 2.5e-06 28.2 2.0 6.1e-05 23.7 0.9 2.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 GAN10237.1 - 1.3e-05 24.9 2.4 3.6e-05 23.5 0.9 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 GAN10237.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GAN10237.1 - 0.0015 17.8 0.1 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAN10237.1 - 0.0037 17.1 0.1 0.39 10.5 0.1 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 GAN10237.1 - 0.0081 15.7 0.1 0.033 13.8 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 GAN10237.1 - 0.01 15.8 0.1 0.11 12.4 0.1 2.3 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 GAN10237.1 - 0.011 15.4 1.0 0.041 13.5 0.2 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAN10237.1 - 0.021 14.7 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold SpuA_C PF18033.1 GAN10237.1 - 0.032 14.3 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 SpuA C-terminal AXE1 PF05448.12 GAN10237.1 - 0.041 12.6 0.0 0.26 9.9 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) LIP PF03583.14 GAN10237.1 - 0.089 12.1 1.2 0.3 10.4 0.6 2.0 2 0 0 2 2 2 0 Secretory lipase PNISR PF15996.5 GAN10238.1 - 0.67 10.2 5.1 0.94 9.7 5.1 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PPP4R2 PF09184.11 GAN10238.1 - 2 8.0 13.1 2.4 7.7 13.1 1.1 1 0 0 1 1 1 0 PPP4R2 Alba PF01918.21 GAN10239.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Alba Neur_chan_memb PF02932.16 GAN10239.1 - 0.4 10.7 4.5 0.55 10.3 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IHABP4_N PF16174.5 GAN10239.1 - 0.43 11.2 11.3 0.6 10.7 11.3 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Mucin PF01456.17 GAN10239.1 - 0.48 10.4 14.0 0.79 9.7 14.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Rtf2 PF04641.12 GAN10239.1 - 0.64 9.3 13.7 0.87 8.9 13.4 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.13 GAN10239.1 - 0.74 8.5 10.8 0.86 8.3 10.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dicty_REP PF05086.12 GAN10239.1 - 1.7 6.6 11.3 2.1 6.2 11.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Coilin_N PF15862.5 GAN10239.1 - 1.7 8.5 11.7 3.5 7.4 11.7 1.5 1 0 0 1 1 1 0 Coilin N-terminus CCDC106 PF15794.5 GAN10239.1 - 2.7 7.6 17.5 4 7.1 17.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 GAN10239.1 - 2.8 6.6 11.3 3.5 6.3 11.3 1.2 1 0 0 1 1 1 0 Presenilin Endostatin PF06482.11 GAN10239.1 - 3.1 7.2 9.9 4.3 6.7 9.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Macoilin PF09726.9 GAN10239.1 - 3.1 6.2 12.6 3.9 5.9 12.6 1.1 1 0 0 1 1 1 0 Macoilin family Sec10 PF07393.11 GAN10239.1 - 3.9 5.8 13.0 5.2 5.3 13.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Ndc1_Nup PF09531.10 GAN10239.1 - 4.2 5.9 9.3 4.9 5.7 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 GAN10239.1 - 5.2 6.2 7.5 6.2 5.9 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ERG4_ERG24 PF01222.17 GAN10240.1 - 2e-147 491.4 12.8 2.4e-147 491.2 12.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAN10240.1 - 0.0047 16.5 0.2 0.0047 16.5 0.2 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF3439 PF11921.8 GAN10240.1 - 0.017 15.0 2.1 0.038 14.0 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAN10240.1 - 0.19 11.7 10.6 0.33 11.0 10.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Septin PF00735.18 GAN10241.1 - 5.7e-112 373.6 0.7 6.7e-112 373.4 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 GAN10241.1 - 4.1e-06 26.9 0.1 1e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAN10241.1 - 0.0014 18.7 2.8 1.2 9.2 0.0 3.1 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 GAN10241.1 - 0.013 15.7 0.0 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAN10241.1 - 0.022 14.1 0.0 0.069 12.5 0.0 2.0 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.27 GAN10241.1 - 0.029 13.9 0.5 0.1 12.2 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain tRNA_synthFbeta PF17759.1 GAN10241.1 - 0.041 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain RsgA_GTPase PF03193.16 GAN10241.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.7 3 1 0 3 3 3 0 RsgA GTPase DUF4140 PF13600.6 GAN10241.1 - 1.8 9.0 7.2 70 3.9 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IPK PF03770.16 GAN10243.1 - 4.6e-51 173.5 0.0 9.5e-51 172.5 0.0 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF202 PF02656.15 GAN10244.1 - 0.00078 19.8 6.9 0.00078 19.8 6.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) VPDSG-CTERM PF18205.1 GAN10244.1 - 0.061 13.1 2.6 0.061 13.1 2.6 2.3 3 0 0 3 3 3 0 VPDSG-CTERM motif Myelin_PLP PF01275.19 GAN10244.1 - 0.12 12.2 4.0 0.14 12.0 4.0 1.0 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) FtsX PF02687.21 GAN10244.1 - 0.2 12.2 5.2 0.3 11.6 5.2 1.4 1 0 0 1 1 1 0 FtsX-like permease family Pox_A9 PF04835.12 GAN10244.1 - 0.78 9.9 3.7 6.5 7.0 0.8 2.3 2 0 0 2 2 2 0 A9 protein conserved region PEP-CTERM PF07589.11 GAN10244.1 - 5.6 7.2 6.3 1.4 9.1 2.2 2.1 2 0 0 2 2 2 0 PEP-CTERM motif Nup188 PF10487.9 GAN10247.1 - 8.9e-75 252.3 15.3 9.9e-56 189.2 3.9 2.4 3 0 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 HU-CCDC81_euk_2 PF18289.1 GAN10247.1 - 0.08 13.1 0.0 43 4.4 0.0 3.8 4 0 0 4 4 4 0 CCDC81 eukaryotic HU domain 2 SRAP PF02586.14 GAN10248.1 - 2e-64 217.1 0.2 3e-64 216.6 0.2 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Choline_transpo PF04515.12 GAN10249.1 - 2.3e-75 253.8 35.7 2.3e-75 253.8 35.7 2.2 1 1 1 2 2 2 1 Plasma-membrane choline transporter Zn_clus PF00172.18 GAN10250.1 - 1.4e-07 31.5 8.8 2.4e-07 30.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 GAN10251.1 - 1.6e-17 63.9 0.0 3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN10251.1 - 5.6e-16 58.9 0.1 2.9e-14 53.3 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAN10251.1 - 6.1e-09 36.5 0.0 2.2e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 GAN10251.1 - 7.6e-08 32.5 0.0 1.9e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RQC PF09382.10 GAN10251.1 - 0.0078 16.0 0.1 0.024 14.4 0.1 1.8 1 1 0 1 1 1 1 RQC domain Osmo_CC PF08946.10 GAN10251.1 - 0.038 14.2 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DivIC PF04977.15 GAN10251.1 - 0.11 12.3 0.9 0.32 10.8 0.9 1.8 1 0 0 1 1 1 0 Septum formation initiator Homeodomain PF00046.29 GAN10252.1 - 1.1e-19 70.0 2.0 1.1e-19 70.0 2.0 2.3 2 0 0 2 2 2 1 Homeodomain DUF3947 PF13135.6 GAN10252.1 - 0.0016 18.6 4.1 0.039 14.1 3.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3947) Cyt-b5 PF00173.28 GAN10253.1 - 2.1e-20 72.6 0.1 4.1e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 GAN10253.1 - 1e-12 48.5 19.6 1e-12 48.5 19.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CPBP PF02517.16 GAN10253.1 - 1.7 9.0 9.7 5.1 7.5 9.7 1.9 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease TMEM189_B_dmain PF10520.9 GAN10253.1 - 7.2 6.7 10.3 0.22 11.6 1.1 2.3 1 1 1 2 2 2 0 B domain of TMEM189, localisation domain DNA_pol_E_B PF04042.16 GAN10254.1 - 4.8e-51 173.1 0.1 7.8e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 GAN10254.1 - 0.0028 17.9 0.1 0.016 15.5 0.1 2.4 1 1 0 1 1 1 1 DNA polymerases epsilon N terminal DNA_pol_D_N PF18018.1 GAN10254.1 - 0.068 13.3 0.1 0.32 11.1 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase delta subunit OB-fold domain Fmp27_WPPW PF10359.9 GAN10255.1 - 5.8e-98 328.8 14.6 5.8e-98 328.8 14.6 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 GAN10255.1 - 3e-97 326.5 9.9 3e-97 326.5 9.9 3.6 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 GAN10255.1 - 3.9e-37 127.8 0.0 1.3e-36 126.1 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 GAN10255.1 - 9.2e-34 116.6 0.3 9.2e-34 116.6 0.3 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 GAN10255.1 - 4.7e-18 65.8 0.1 4.7e-18 65.8 0.1 3.7 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain NTS PF15447.6 GAN10255.1 - 0.19 12.3 0.3 0.44 11.1 0.3 1.6 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 MS_channel PF00924.18 GAN10256.1 - 8.3e-16 58.1 0.5 1.4e-15 57.4 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 GAN10256.1 - 7.4e-05 22.0 0.3 0.00027 20.2 0.3 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAN10256.1 - 0.00011 21.8 0.3 0.0004 20.1 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain ATP_synt_H PF05493.13 GAN10256.1 - 0.0021 18.5 0.8 0.0065 16.9 0.8 1.8 1 0 0 1 1 1 1 ATP synthase subunit H EF-hand_5 PF13202.6 GAN10256.1 - 0.004 16.6 1.8 0.0082 15.6 0.4 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 GAN10256.1 - 0.027 14.3 0.1 0.079 12.8 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 GAN10256.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain pair Chitin_synth_2 PF03142.15 GAN10257.1 - 4.4e-246 817.6 1.0 6.4e-246 817.0 1.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAN10257.1 - 1.1e-10 41.9 0.0 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAN10257.1 - 8.3e-10 38.9 7.9 4.5e-09 36.5 7.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Sugar_tr PF00083.24 GAN10258.1 - 8.5e-109 364.4 29.4 6.5e-89 298.9 16.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAN10258.1 - 8.5e-35 120.3 19.3 8.5e-35 120.3 19.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN10258.1 - 1.8e-06 26.7 3.8 1.8e-06 26.7 3.8 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 GAN10258.1 - 1.8e-06 26.8 30.4 3.4e-05 22.6 4.6 3.9 3 1 1 4 4 4 3 MFS/sugar transport protein PSI PF01437.25 GAN10258.1 - 0.00032 21.2 4.7 0.00066 20.2 4.7 1.5 1 0 0 1 1 1 1 Plexin repeat MFS_1_like PF12832.7 GAN10258.1 - 0.084 11.7 14.5 0.83 8.4 3.2 2.5 1 1 1 2 2 2 0 MFS_1 like family E3_UFM1_ligase PF09743.9 GAN10258.1 - 0.11 12.1 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 SWIRM-assoc_2 PF16496.5 GAN10259.1 - 7.2e-36 124.0 0.1 7.2e-36 124.0 0.1 2.7 2 1 0 3 3 3 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 GAN10259.1 - 3.1e-28 97.9 0.1 8.6e-28 96.5 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 GAN10259.1 - 3.7e-10 39.8 0.7 8.1e-10 38.7 0.7 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN10259.1 - 1.4e-06 28.4 1.7 4.6e-06 26.8 1.7 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRCT_2 PF16589.5 GAN10259.1 - 0.00043 20.6 0.1 0.0032 17.8 0.1 2.4 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SWIRM-assoc_1 PF16495.5 GAN10259.1 - 0.001 19.0 8.9 0.001 19.0 8.9 2.7 2 0 0 2 2 2 1 SWIRM-associated region 1 LIG3_BRCT PF16759.5 GAN10259.1 - 0.12 12.7 0.3 0.64 10.4 0.0 2.4 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Mit_KHE1 PF10173.9 GAN10259.1 - 4.9 7.2 11.2 13 5.8 11.2 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DOT1 PF08123.13 GAN10260.1 - 8.3e-69 231.2 0.1 1.4e-68 230.5 0.1 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 GAN10260.1 - 1.6e-05 24.8 0.0 5.2e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN10260.1 - 2.4e-05 25.0 0.0 7.4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN10260.1 - 0.00018 22.1 0.1 0.00089 19.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN10260.1 - 0.0012 19.5 0.1 0.006 17.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN10260.1 - 0.0022 17.9 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 GAN10260.1 - 0.024 14.9 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 GAN10260.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 GAN10260.1 - 0.091 12.2 0.0 0.31 10.5 0.0 1.9 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 GAN10260.1 - 0.098 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Macoilin PF09726.9 GAN10260.1 - 1.4 7.4 10.1 1.7 7.1 10.1 1.1 1 0 0 1 1 1 0 Macoilin family MARVEL PF01284.23 GAN10261.1 - 0.00027 21.0 6.3 0.00037 20.6 6.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain RDD PF06271.12 GAN10261.1 - 0.086 13.0 3.7 0.12 12.6 0.9 2.1 2 0 0 2 2 2 0 RDD family TssN PF17555.2 GAN10261.1 - 0.19 11.1 6.5 0.26 10.6 6.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN FixQ PF05545.11 GAN10261.1 - 6.9 6.7 12.2 0.11 12.4 2.5 2.6 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Alk_phosphatase PF00245.20 GAN10262.1 - 1.6e-98 330.4 0.0 2e-98 330.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAN10262.1 - 6.1e-05 22.5 0.0 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF3081 PF11280.8 GAN10263.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) SNase PF00565.17 GAN10264.1 - 3e-67 223.9 0.2 3e-21 75.9 0.0 5.2 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 GAN10264.1 - 4.9e-30 104.1 0.0 1.1e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 GAN10264.1 - 0.06 13.8 0.0 0.37 11.3 0.0 2.4 2 0 0 2 2 2 0 Agenet domain DUF4154 PF13689.6 GAN10264.1 - 0.13 12.4 0.1 0.62 10.3 0.1 2.1 2 0 0 2 2 2 0 YfiR/HmsC-like Glyco_transf_20 PF00982.21 GAN10265.1 - 5.4e-163 543.1 0.0 7.7e-163 542.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAN10265.1 - 1.1e-74 250.5 0.0 2.2e-74 249.5 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 GAN10265.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Ribosomal_L12 PF00542.19 GAN10266.1 - 5e-21 74.8 11.9 1.1e-20 73.8 9.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GAN10266.1 - 1.1e-16 60.2 0.6 1.1e-16 60.2 0.6 3.4 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain DUF2267 PF10025.9 GAN10266.1 - 0.013 15.8 0.3 0.023 15.0 0.3 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Ras PF00071.22 GAN10267.1 - 4.4e-52 176.0 0.0 5.4e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN10267.1 - 3.9e-31 107.8 0.0 7.2e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN10267.1 - 8.1e-13 48.2 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN10267.1 - 0.00072 19.2 0.0 0.0074 15.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN10267.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN10267.1 - 0.0018 17.7 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAN10267.1 - 0.011 15.6 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 GAN10267.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAN10267.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Clathrin_lg_ch PF01086.17 GAN10268.1 - 3.1e-50 171.4 17.0 3.7e-50 171.2 17.0 1.1 1 0 0 1 1 1 1 Clathrin light chain PSII_Pbs27 PF13326.6 GAN10268.1 - 0.00063 20.1 0.3 0.00077 19.8 0.3 1.3 1 0 0 1 1 1 1 Photosystem II Pbs27 CdiI_2 PF18593.1 GAN10268.1 - 0.33 11.6 7.1 4.2 8.1 0.1 2.9 3 0 0 3 3 3 0 CdiI immunity protein Talin_middle PF09141.10 GAN10268.1 - 0.47 10.5 4.9 0.32 11.0 2.8 1.8 1 1 0 1 1 1 0 Talin, middle domain ABC_membrane PF00664.23 GAN10269.1 - 2.4e-50 171.7 32.5 2.2e-34 119.4 12.9 4.3 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 GAN10269.1 - 6.6e-21 75.3 0.0 3.2e-14 53.6 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_25 PF13481.6 GAN10269.1 - 0.01 15.4 1.0 0.51 9.9 0.8 3.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAN10269.1 - 0.025 15.0 0.0 3.1 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GAN10269.1 - 0.03 14.6 0.1 1.6 9.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain PTPRCAP PF15713.5 GAN10269.1 - 0.51 10.6 6.6 1.2 9.4 6.6 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 GAN10269.1 - 0.62 9.7 3.2 1.9 8.2 3.2 1.8 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GAN10269.1 - 0.66 9.2 2.3 1.2 8.4 2.3 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 GAN10269.1 - 2.4 8.8 6.2 6.5 7.4 6.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 GAN10269.1 - 6.6 4.7 7.8 13 3.7 7.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Sulfotransfer_4 PF17784.1 GAN10270.1 - 7.8e-61 205.6 0.0 9e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAN10270.1 - 0.0042 17.5 0.3 0.023 15.1 0.3 2.1 1 1 0 1 1 1 1 Sulfotransferase family Pkinase PF00069.25 GAN10271.1 - 2.2e-62 210.8 0.5 2.9e-62 210.4 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain PhosphMutase PF10143.9 GAN10271.1 - 6.8e-49 166.0 0.0 1.2e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 GAN10271.1 - 7e-24 84.5 0.0 1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Pkinase_Tyr PF07714.17 GAN10271.1 - 7.3e-20 71.3 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Phosphodiest PF01663.22 GAN10271.1 - 1.5e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase APH PF01636.23 GAN10271.1 - 3.5e-05 23.8 0.0 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN10271.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 GAN10271.1 - 0.037 13.6 0.2 0.079 12.5 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Alk_phosphatase PF00245.20 GAN10271.1 - 0.062 12.3 0.1 0.098 11.6 0.1 1.2 1 0 0 1 1 1 0 Alkaline phosphatase Sulfatase PF00884.23 GAN10271.1 - 0.064 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Sulfatase Kdo PF06293.14 GAN10271.1 - 0.067 12.5 0.3 0.14 11.5 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Plectin PF00681.20 GAN10271.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat Tox-REase-9 PF15650.6 GAN10271.1 - 0.26 11.6 0.9 0.6 10.4 0.3 1.9 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 9 DDT PF02791.17 GAN10273.1 - 0.0063 16.8 0.1 0.019 15.3 0.1 1.8 1 0 0 1 1 1 1 DDT domain Cluap1 PF10234.9 GAN10273.1 - 5.6 6.3 19.5 0.33 10.3 13.7 1.9 2 0 0 2 2 2 0 Clusterin-associated protein-1 Asparaginase PF00710.20 GAN10274.1 - 1.1e-59 201.2 0.0 2.4e-59 200.1 0.0 1.6 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 GAN10274.1 - 1e-30 106.3 0.0 2.3e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 GAN10274.1 - 2.7e-16 59.9 0.0 3e-12 47.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN10274.1 - 5.9e-15 55.1 0.3 7.8e-10 38.8 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN10274.1 - 1.2e-11 44.9 0.3 9.6e-06 26.1 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAN10274.1 - 5.5e-10 39.2 0.3 4.5e-06 26.9 0.1 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 GAN10274.1 - 5.7e-07 29.3 2.2 0.00092 19.5 0.1 4.3 5 0 0 5 5 5 2 Ankyrin repeat zf-DNL PF05180.12 GAN10274.1 - 0.11 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 DNL zinc finger Med15_fungi PF05397.12 GAN10275.1 - 4.7e-34 117.0 0.5 4.7e-34 117.0 0.5 12.0 8 4 4 12 12 12 1 Mediator complex subunit 15 DPBB_1 PF03330.18 GAN10276.1 - 4.5e-05 23.7 0.2 0.00012 22.3 0.2 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN10276.1 - 0.01 15.7 0.8 0.014 15.3 0.8 1.2 1 0 0 1 1 1 0 Barwin family GTP_EFTU PF00009.27 GAN10279.1 - 1.7e-52 177.8 0.0 2.6e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 GAN10279.1 - 6.6e-48 161.3 0.7 3e-47 159.2 1.1 1.9 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 GAN10279.1 - 4e-22 78.1 0.0 9.5e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAN10279.1 - 1.2e-06 28.8 0.1 4e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAN10279.1 - 1.4e-06 28.1 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 GAN10279.1 - 2.4e-05 24.3 0.0 5.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 GAN10279.1 - 0.00017 21.2 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAN10279.1 - 0.011 15.2 0.2 0.033 13.6 0.0 2.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 GAN10279.1 - 0.048 13.7 0.2 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_2 PF07724.14 GAN10280.1 - 7.5e-54 182.4 4.1 6.9e-53 179.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAN10280.1 - 1.5e-35 121.2 2.1 1.5e-35 121.2 2.1 2.8 1 1 0 2 2 2 1 AAA lid domain AAA PF00004.29 GAN10280.1 - 1.2e-23 84.0 0.1 3.1e-12 47.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAN10280.1 - 1.2e-23 82.9 0.2 1.2e-23 82.9 0.2 2.6 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAN10280.1 - 8.4e-16 58.2 2.3 1.9e-10 40.9 0.0 3.8 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAN10280.1 - 4e-10 40.3 0.2 0.0065 16.9 0.0 4.5 3 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 GAN10280.1 - 9.3e-10 38.5 0.4 2.8e-06 27.1 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 GAN10280.1 - 9.7e-08 32.4 4.5 0.036 14.3 0.0 4.7 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 GAN10280.1 - 2.7e-07 30.2 0.1 0.029 13.8 0.0 3.7 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAN10280.1 - 9e-07 28.8 0.0 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 GAN10280.1 - 1.6e-06 27.7 0.0 0.003 17.0 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 GAN10280.1 - 6.9e-06 25.7 0.0 0.028 13.9 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 GAN10280.1 - 2.5e-05 24.3 0.7 0.31 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 GAN10280.1 - 7.2e-05 22.6 2.0 0.77 9.5 0.0 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 GAN10280.1 - 0.00012 21.9 0.0 0.057 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAN10280.1 - 0.00014 22.2 0.0 0.86 10.0 0.0 3.4 3 0 0 3 3 3 2 RNA helicase TsaE PF02367.17 GAN10280.1 - 0.00028 20.9 0.0 0.75 9.8 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 GAN10280.1 - 0.00031 20.9 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 GAN10280.1 - 0.00032 21.2 1.5 0.49 10.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 GAN10280.1 - 0.001 19.0 0.3 0.25 11.2 0.0 3.2 3 0 0 3 3 3 1 NACHT domain RsgA_GTPase PF03193.16 GAN10280.1 - 0.0019 18.1 0.2 2.4 8.0 0.0 3.0 3 0 0 3 3 2 1 RsgA GTPase DNA_pol3_delta2 PF13177.6 GAN10280.1 - 0.0024 17.7 0.1 4.1 7.2 0.0 3.8 4 0 0 4 4 4 1 DNA polymerase III, delta subunit Bac_DnaA PF00308.18 GAN10280.1 - 0.0033 17.3 0.5 2.7 7.8 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein ABC_tran PF00005.27 GAN10280.1 - 0.01 16.4 5.5 0.21 12.1 0.0 3.7 3 1 0 3 3 2 0 ABC transporter T3SS_needle_E PF08988.10 GAN10280.1 - 0.019 15.1 1.4 5.6 7.2 0.0 3.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle SRP54 PF00448.22 GAN10280.1 - 0.031 13.9 0.2 3.9 7.0 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 GAN10280.1 - 0.048 13.4 0.1 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 GAN10280.1 - 0.057 13.2 0.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 GAN10280.1 - 0.073 13.2 0.3 24 5.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 GAN10280.1 - 0.11 12.9 14.4 2.7 8.5 6.7 4.0 4 0 0 4 4 3 0 AAA domain CbiA PF01656.23 GAN10280.1 - 0.12 12.5 0.1 28 4.8 0.0 3.3 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fez1 PF06818.15 GAN10280.1 - 0.13 12.7 14.4 0.42 11.0 14.4 1.8 1 0 0 1 1 1 0 Fez1 AAA_28 PF13521.6 GAN10280.1 - 0.16 12.2 2.3 21 5.3 0.0 3.9 4 1 0 4 4 3 0 AAA domain HAUS2 PF15003.6 GAN10280.1 - 0.18 11.5 5.3 0.26 11.0 4.2 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF1640 PF07798.11 GAN10280.1 - 0.59 10.2 9.4 1.5 8.9 9.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TIP49 PF06068.13 GAN10280.1 - 0.77 8.9 12.5 2.2 7.4 0.0 3.7 4 0 0 4 4 3 0 TIP49 P-loop domain Prefoldin PF02996.17 GAN10280.1 - 1.4 8.8 8.3 0.96 9.4 0.4 3.5 3 1 0 3 3 3 0 Prefoldin subunit AAA_30 PF13604.6 GAN10280.1 - 1.7 8.3 7.7 5 6.8 0.6 3.8 3 2 0 3 3 3 0 AAA domain Atg14 PF10186.9 GAN10280.1 - 4.2 6.4 11.4 7.3 5.6 11.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Complex1_LYR PF05347.15 GAN10281.1 - 0.00011 22.2 0.2 0.00014 21.8 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAN10281.1 - 0.1 13.3 0.1 0.13 13.1 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like NDUFA12 PF05071.16 GAN10282.1 - 6.3e-28 97.5 2.5 7.8e-28 97.2 2.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WD40 PF00400.32 GAN10283.1 - 1.1e-38 130.4 1.3 2.7e-05 24.8 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10283.1 - 2.8e-21 75.6 0.0 0.00023 21.4 0.0 6.1 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN10283.1 - 1.2e-08 35.1 0.1 7.5e-05 22.7 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CSTF1_dimer PF16699.5 GAN10283.1 - 6.5e-08 32.2 0.1 3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Cleavage stimulation factor subunit 1, dimerisation domain Ge1_WD40 PF16529.5 GAN10283.1 - 1.1e-07 31.2 0.2 0.034 13.1 0.1 3.4 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAN10283.1 - 4.8e-05 22.1 0.1 0.073 11.6 0.0 3.0 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 GAN10283.1 - 4.9e-05 22.2 0.8 0.29 9.7 0.2 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 GAN10283.1 - 7.9e-05 21.7 0.1 0.16 10.9 0.0 3.0 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Phi29_Phage_SSB PF17427.2 GAN10283.1 - 0.016 15.4 0.6 0.37 11.0 0.2 3.1 3 1 1 4 4 4 0 Phage Single-stranded DNA-binding protein HPS3_N PF14761.6 GAN10283.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 FA_desaturase PF00487.24 GAN10284.1 - 1.3e-24 87.5 11.4 1.3e-24 87.5 11.4 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 GAN10284.1 - 9.3e-10 37.8 1.0 1.8e-09 36.9 1.0 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FH2 PF02181.23 GAN10285.1 - 3.7e-76 256.7 10.9 3.7e-76 256.7 10.9 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Lon_C PF05362.13 GAN10285.1 - 1.2e-72 243.8 0.1 2.1e-72 243.0 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Drf_GBD PF06371.13 GAN10285.1 - 9.8e-35 119.8 4.5 5.7e-29 101.0 0.0 3.8 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain LON_substr_bdg PF02190.16 GAN10285.1 - 2.9e-28 99.2 0.2 2.9e-28 99.2 0.2 3.0 3 0 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAN10285.1 - 1.4e-22 80.6 0.0 1.1e-21 77.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Drf_FH3 PF06367.16 GAN10285.1 - 2.6e-22 79.4 0.1 2.6e-22 79.4 0.1 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain ChlI PF13541.6 GAN10285.1 - 2.6e-05 24.0 0.0 6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 GAN10285.1 - 0.00025 20.1 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain HALZ PF02183.18 GAN10285.1 - 0.00054 20.1 0.4 0.00054 20.1 0.4 2.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper AAA_5 PF07728.14 GAN10285.1 - 0.00081 19.4 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAN10285.1 - 0.0019 18.5 0.0 0.13 12.5 0.0 3.2 1 1 0 1 1 1 1 AAA domain NanE PF04131.14 GAN10285.1 - 0.0024 17.1 0.1 0.0069 15.6 0.0 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase RuvB_N PF05496.12 GAN10285.1 - 0.0024 17.6 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAN10285.1 - 0.0033 17.8 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 GAN10285.1 - 0.004 17.1 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_3 PF07726.11 GAN10285.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAN10285.1 - 0.031 14.8 2.8 0.048 14.2 0.0 3.0 3 0 0 3 3 1 0 AAA domain AAA_16 PF13191.6 GAN10285.1 - 0.062 13.7 0.0 0.062 13.7 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain AAA_33 PF13671.6 GAN10285.1 - 0.096 12.8 0.0 0.39 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAN10285.1 - 3.1 8.3 0.0 3.1 8.3 0.0 5.3 5 0 0 5 5 4 0 AAA domain Usp PF00582.26 GAN10286.1 - 1.5e-17 64.4 0.0 1.9e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Pkinase PF00069.25 GAN10287.1 - 2.9e-65 220.2 0.0 3.5e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10287.1 - 4.4e-24 85.2 0.0 5.8e-24 84.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN10287.1 - 6e-08 32.3 0.0 1.4e-05 24.6 0.0 2.3 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 GAN10287.1 - 0.0039 16.6 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN10287.1 - 0.0096 15.9 0.0 0.043 13.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAN10287.1 - 0.014 14.2 1.1 2 7.1 0.1 2.1 1 1 1 2 2 2 0 Fungal protein kinase WD40 PF00400.32 GAN10288.1 - 2.1e-20 72.7 8.6 3e-06 27.9 0.0 7.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10288.1 - 8e-05 22.9 0.2 9.7 6.6 0.0 5.7 4 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN10288.1 - 0.0061 15.3 0.0 0.16 10.6 0.0 2.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Sporozoite_P67 PF05642.11 GAN10289.1 - 0.18 9.8 11.6 0.2 9.7 11.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 GAN10291.1 - 3.2e-60 203.7 0.0 5e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10291.1 - 2.8e-29 102.2 0.0 4.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAN10291.1 - 2.4e-08 34.5 0.3 1.2e-07 32.3 0.3 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain PX PF00787.24 GAN10291.1 - 5.1e-05 23.2 3.5 5.1e-05 23.2 3.5 2.1 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 GAN10291.1 - 0.00062 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GAN10291.1 - 0.0022 17.7 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAN10291.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.19 GAN10291.1 - 0.17 12.2 4.1 1.7 9.0 0.8 2.6 1 1 1 2 2 2 0 Regulator of G protein signaling domain Peptidase_S8 PF00082.22 GAN10292.1 - 4.4e-41 141.1 2.5 7.8e-41 140.3 2.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAN10292.1 - 5.9e-15 55.7 0.2 1.2e-14 54.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 ADH_N PF08240.12 GAN10293.1 - 1.2e-23 83.0 5.2 1.2e-23 83.0 5.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAN10293.1 - 5.4e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN10293.1 - 0.0027 18.8 0.0 0.0039 18.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAN10293.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L31e PF01198.19 GAN10294.1 - 1.1e-37 128.1 3.0 1.5e-37 127.7 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e ERAP1_C PF11838.8 GAN10294.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain CDP-OH_P_transf PF01066.21 GAN10295.1 - 3.4e-17 63.0 0.3 3.4e-17 63.0 0.3 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CNH PF00780.22 GAN10296.1 - 1.9e-57 195.0 0.0 3.4e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAN10296.1 - 6.8e-35 120.9 1.4 1.3e-34 120.0 0.2 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 GAN10296.1 - 1.1e-31 109.7 0.3 1.1e-31 109.7 0.3 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 GAN10296.1 - 3.3e-10 39.9 0.0 7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PPR_2 PF13041.6 GAN10297.1 - 4.8e-60 199.6 33.0 3e-08 33.7 0.0 15.1 9 4 8 17 17 15 10 PPR repeat family PPR PF01535.20 GAN10297.1 - 1.2e-48 160.0 32.2 0.0013 18.8 0.0 18.2 20 0 0 20 20 18 10 PPR repeat PPR_3 PF13812.6 GAN10297.1 - 1.3e-38 130.9 24.3 6.5e-09 35.7 0.0 10.3 7 3 4 12 12 11 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAN10297.1 - 2.8e-37 126.1 0.2 0.00016 21.3 0.0 12.6 13 0 0 13 13 13 7 PPR repeat PPR_long PF17177.4 GAN10297.1 - 3.3e-35 121.4 9.9 5e-09 35.8 0.4 6.0 4 1 3 7 7 7 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAN10297.1 - 7.1e-08 32.6 0.0 20 6.3 0.0 8.0 9 1 0 9 9 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10297.1 - 1.6e-07 31.7 1.0 0.13 12.8 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat MRP-S27 PF10037.9 GAN10297.1 - 0.00024 20.1 8.4 0.11 11.3 0.4 4.1 5 1 0 5 5 5 2 Mitochondrial 28S ribosomal protein S27 TPR_15 PF13429.6 GAN10297.1 - 0.0019 17.5 7.1 2.4 7.3 0.4 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat Clathrin PF00637.20 GAN10297.1 - 0.0044 16.9 14.8 0.084 12.7 0.8 6.0 3 1 1 5 5 5 1 Region in Clathrin and VPS Rcd1 PF04078.13 GAN10297.1 - 0.0056 16.0 0.2 0.021 14.2 0.2 2.0 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like TPR_7 PF13176.6 GAN10297.1 - 0.017 15.1 0.3 8.9 6.6 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAN10297.1 - 0.018 15.0 0.2 21 5.0 0.1 4.2 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_1 PF00515.28 GAN10297.1 - 0.041 13.7 2.9 46 4.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10297.1 - 0.084 13.0 1.8 38 4.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RPM2 PF08579.11 GAN10297.1 - 1.4 9.3 4.9 13 6.2 0.0 4.7 5 1 0 5 5 4 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_8 PF13181.6 GAN10297.1 - 3.7 8.0 13.7 28 5.3 0.1 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN10297.1 - 4.1 8.3 9.7 1.6e+02 3.3 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat ETF_QO PF05187.13 GAN10297.1 - 5.2 7.3 5.5 6.2 7.0 0.1 3.1 3 0 0 3 3 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S RasGEF PF00617.19 GAN10298.1 - 1.3e-54 185.0 0.4 5.6e-54 183.0 0.4 2.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN10298.1 - 1e-25 90.0 0.7 7.2e-25 87.3 0.4 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 GAN10298.1 - 2.9e-14 52.4 0.1 6e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain WW PF00397.26 GAN10298.1 - 2.2e-12 46.8 7.5 1.2e-07 31.7 0.3 2.7 2 0 0 2 2 2 2 WW domain SH3_9 PF14604.6 GAN10298.1 - 2.2e-11 43.4 0.1 4.3e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN10298.1 - 2.2e-09 36.9 0.1 4.5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Cyclin_N PF00134.23 GAN10298.1 - 1e-06 28.5 0.2 0.0017 18.1 0.0 3.0 2 0 0 2 2 2 2 Cyclin, N-terminal domain Hist_deacetyl PF00850.19 GAN10299.1 - 1.5e-82 277.5 0.0 2.3e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ammonium_transp PF00909.21 GAN10300.1 - 1e-113 380.0 30.9 1.2e-113 379.8 30.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MAP17 PF15807.5 GAN10300.1 - 0.17 12.1 0.3 0.52 10.5 0.3 1.8 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PAP_PilO PF06864.12 GAN10301.1 - 0.05 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) HEAT PF02985.22 GAN10302.1 - 3.9e-09 36.0 7.4 7.6 7.1 0.2 8.1 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 GAN10302.1 - 1.5e-07 31.7 6.0 0.04 14.3 0.0 6.5 5 2 2 7 7 7 2 HEAT repeats Cnd1 PF12717.7 GAN10302.1 - 0.001 19.1 4.0 1.8 8.6 0.1 5.1 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAN10302.1 - 0.061 13.4 4.8 0.49 10.5 0.1 4.4 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat CTV_P13 PF06922.11 GAN10302.1 - 0.093 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein HEAT_EZ PF13513.6 GAN10302.1 - 0.43 11.1 13.3 16 6.1 0.1 6.5 7 1 1 8 8 8 0 HEAT-like repeat MFS_1 PF07690.16 GAN10303.1 - 2.2e-47 161.7 27.4 2.2e-47 161.7 27.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN10303.1 - 4.3e-07 29.2 13.8 4.3e-07 29.2 13.8 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 GAN10303.1 - 5.2 5.8 19.7 14 4.4 11.8 3.1 2 1 0 2 2 2 0 MFS_1 like family ECH_1 PF00378.20 GAN10304.1 - 1.3e-27 96.8 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN10304.1 - 2.2e-15 57.0 0.1 2.5e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Arf PF00025.21 GAN10305.1 - 1.7e-75 252.3 0.1 1.9e-75 252.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAN10305.1 - 1.1e-15 57.9 0.1 1.5e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN10305.1 - 1.2e-13 51.0 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAN10305.1 - 1.3e-11 44.3 2.7 2.1e-07 30.5 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAN10305.1 - 4.6e-11 42.5 0.0 5.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAN10305.1 - 3e-10 39.9 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN10305.1 - 6.9e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAN10305.1 - 0.0058 16.0 0.1 0.0086 15.4 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Phosducin PF02114.16 GAN10306.1 - 1.8e-15 56.6 0.1 1.4e-14 53.7 0.1 2.0 1 1 0 1 1 1 1 Phosducin P5CR_dimer PF14748.6 GAN10307.1 - 5.4e-35 119.8 0.9 1.1e-34 118.7 0.9 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAN10307.1 - 6.5e-18 65.1 0.0 1.8e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 GAN10307.1 - 0.014 15.4 0.2 0.055 13.4 0.2 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.24 GAN10307.1 - 0.047 14.1 0.0 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Rep_fac-A_3 PF08661.11 GAN10308.1 - 2.2e-25 89.0 0.0 2.5e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF4431 PF14485.6 GAN10308.1 - 0.053 13.3 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) WGG PF10273.9 GAN10309.1 - 2.4e-29 101.8 1.2 2.4e-29 101.8 1.2 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Peptidase_C14 PF00656.22 GAN10309.1 - 0.031 14.2 0.1 0.86 9.5 0.1 2.1 1 1 1 2 2 2 0 Caspase domain NOA36 PF06524.12 GAN10309.1 - 1.1 8.6 10.1 1.5 8.1 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein zf-PARP PF00645.18 GAN10310.1 - 1.1e-12 48.6 0.7 1.1e-12 48.6 0.7 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region SWIRM-assoc_2 PF16496.5 GAN10310.1 - 0.0022 17.0 13.4 0.0024 16.8 13.4 1.2 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal Apt1 PF10351.9 GAN10310.1 - 0.28 10.0 12.7 0.36 9.6 12.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain 40S_SA_C PF16122.5 GAN10310.1 - 0.97 10.8 10.9 2.6 9.4 10.9 1.8 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus MDM10 PF12519.8 GAN10310.1 - 5 5.9 8.7 5.5 5.7 8.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CDC45 PF02724.14 GAN10310.1 - 9.6 4.4 14.2 12 4.0 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PRP21_like_P PF12230.8 GAN10310.1 - 9.8 6.0 25.2 4.9 7.0 19.8 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein G-patch PF01585.23 GAN10311.1 - 1.2e-15 57.1 3.0 2e-15 56.4 1.4 2.3 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 GAN10311.1 - 6.2e-10 38.9 0.0 1.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 GAN10311.1 - 6.3e-07 29.4 0.1 6.3e-07 29.4 0.1 3.3 3 0 0 3 3 3 1 G-patch domain HEPN_Swt1 PF18731.1 GAN10311.1 - 0.16 12.3 1.9 0.44 10.9 0.8 2.3 2 0 0 2 2 2 0 Swt1-like HEPN NINJA_B PF16136.5 GAN10311.1 - 2.1 8.8 11.0 0.05 14.0 2.6 2.7 3 0 0 3 3 3 0 Putative nuclear localisation signal RNaseH_C PF09293.10 GAN10312.1 - 0.0072 16.7 1.1 0.0072 16.7 1.1 1.4 1 1 0 1 1 1 1 T4 RNase H, C terminal FtsK_alpha PF17854.1 GAN10312.1 - 0.072 13.2 2.3 0.089 12.9 2.3 1.2 1 0 0 1 1 1 0 FtsK alpha domain Sec2p PF06428.11 GAN10313.1 - 0.00077 19.4 0.7 0.00077 19.4 0.7 3.5 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p SUIM_assoc PF16619.5 GAN10313.1 - 0.0012 18.9 3.5 0.0012 18.9 3.5 5.4 6 0 0 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 Marek_SORF3 PF07153.11 GAN10313.1 - 0.042 13.2 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Marek's disease-like virus SORF3 protein DUF2203 PF09969.9 GAN10313.1 - 0.4 11.4 12.2 6.6 7.5 2.5 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF2796 PF10986.8 GAN10313.1 - 1.1 9.2 20.1 0.11 12.5 4.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) GPI-anchored PF10342.9 GAN10314.1 - 3.5e-14 53.3 1.8 3.5e-14 53.3 1.8 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.32 GAN10316.1 - 2.6e-30 104.0 21.1 7e-07 29.9 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat LSM PF01423.22 GAN10316.1 - 4.7e-15 55.0 1.7 4.2e-14 52.0 0.8 2.4 2 0 0 2 2 2 1 LSM domain ANAPC4_WD40 PF12894.7 GAN10316.1 - 4.1e-12 46.2 6.3 0.017 15.4 0.0 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN10316.1 - 3.8e-06 26.9 0.1 0.93 9.3 0.0 3.8 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAN10316.1 - 0.0014 17.2 0.1 0.25 9.8 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain CLTH PF10607.9 GAN10316.1 - 0.0043 16.9 0.3 0.0072 16.2 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_like PF17005.5 GAN10316.1 - 0.026 13.9 0.9 0.14 11.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Hfq PF17209.3 GAN10316.1 - 0.059 13.0 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Hfq protein Cytochrom_C PF00034.21 GAN10317.1 - 2.6e-13 50.9 0.2 4e-13 50.3 0.2 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GAN10317.1 - 1.9e-08 34.5 4.5 2.3e-07 31.1 4.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAN10317.1 - 0.0014 18.3 0.3 0.024 14.3 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 GAN10317.1 - 0.036 14.7 0.0 0.039 14.6 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase PGI PF00342.19 GAN10319.1 - 1.8e-257 854.7 0.7 2.2e-257 854.4 0.7 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase MAF_flag10 PF01973.18 GAN10319.1 - 0.028 14.1 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF115 PI3_PI4_kinase PF00454.27 GAN10320.1 - 9e-33 114.1 0.5 2.7e-31 109.3 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 GAN10320.1 - 3.4e-10 39.7 0.0 1.2e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 GAN10320.1 - 0.00012 21.6 0.1 0.00027 20.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Myb_DNA-binding PF00249.31 GAN10322.1 - 2.7e-38 129.9 5.8 3.3e-15 56.0 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN10322.1 - 8.7e-34 115.6 1.2 5e-16 58.7 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAN10322.1 - 0.00047 20.5 5.6 8.8 6.8 0.0 3.6 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 GAN10322.1 - 0.022 14.8 0.0 4.8 7.3 0.0 3.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 GAN10322.1 - 0.041 14.2 9.1 0.84 10.0 1.6 3.6 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RR_TM4-6 PF06459.12 GAN10322.1 - 0.098 12.5 4.6 0.15 11.9 4.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.11 GAN10322.1 - 0.42 10.6 7.7 0.68 9.9 7.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Dynamin_N PF00350.23 GAN10322.1 - 0.75 9.8 3.0 1.3 9.1 3.0 1.3 1 0 0 1 1 1 0 Dynamin family PTPRCAP PF15713.5 GAN10322.1 - 2 8.7 11.8 4.2 7.6 11.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SET PF00856.28 GAN10323.1 - 3e-14 53.8 0.2 5.2e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAN10323.1 - 0.00068 19.7 12.7 0.00068 19.7 12.7 2.0 2 0 0 2 2 2 1 MYND finger HTH_21 PF13276.6 GAN10323.1 - 0.03 14.5 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 HTH-like domain IPK PF03770.16 GAN10324.1 - 2.7e-44 151.4 0.0 4.5e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Opi1 PF08618.10 GAN10325.1 - 5.6e-59 200.5 16.1 2.3e-48 165.5 9.8 3.1 1 1 1 3 3 3 3 Transcription factor Opi1 HAUS-augmin3 PF14932.6 GAN10325.1 - 0.015 14.9 0.8 0.026 14.1 0.2 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Fes1 PF08609.10 GAN10325.1 - 0.061 14.2 3.7 5.6 7.9 0.0 3.3 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF1640 PF07798.11 GAN10326.1 - 3.5e-61 206.3 11.1 4e-61 206.1 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 GAN10326.1 - 0.0002 21.5 1.0 0.0011 19.2 1.1 2.3 2 1 0 2 2 2 1 Homeobox associated leucine zipper FlaC_arch PF05377.11 GAN10326.1 - 0.16 12.4 5.7 2.1 8.8 1.6 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 GAN10326.1 - 0.22 11.6 9.1 1.2 9.3 1.6 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation Cep57_MT_bd PF06657.13 GAN10326.1 - 0.47 11.0 10.3 2.6 8.6 0.6 3.2 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 FeoB_Cyto PF17910.1 GAN10326.1 - 0.84 10.2 7.3 1.6 9.3 1.2 2.9 3 0 0 3 3 3 0 FeoB cytosolic helical domain cwf21 PF08312.12 GAN10326.1 - 1.1 9.4 6.6 1.4 9.1 2.3 2.6 2 1 0 2 2 2 0 cwf21 domain DivIC PF04977.15 GAN10326.1 - 3.5 7.5 10.8 0.77 9.6 5.1 2.5 2 1 0 2 2 2 0 Septum formation initiator YabA PF06156.13 GAN10326.1 - 4 8.1 9.9 3.4 8.4 5.3 2.7 1 1 2 3 3 3 0 Initiation control protein YabA Remorin_C PF03763.13 GAN10326.1 - 5 7.1 10.0 4.3 7.3 8.3 1.8 1 1 0 1 1 1 0 Remorin, C-terminal region Tantalus PF15386.6 GAN10327.1 - 0.13 12.4 6.7 0.79 9.9 0.5 2.3 1 1 1 2 2 2 0 Drosophila Tantalus-like Ribosomal_L22 PF00237.19 GAN10328.1 - 4.6e-26 91.0 0.3 7.8e-26 90.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DHDPS PF00701.22 GAN10329.1 - 5e-49 166.5 0.0 5.6e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family eIF_4EBP PF05456.11 GAN10330.1 - 3.9e-09 36.5 0.1 4.6e-09 36.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Stm1_N PF09598.10 GAN10330.1 - 0.25 12.2 0.4 0.25 12.2 0.4 2.0 1 1 1 2 2 2 0 Stm1 Abhydrolase_3 PF07859.13 GAN10331.1 - 5.7e-57 193.0 0.1 7.4e-57 192.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAN10331.1 - 0.0003 19.8 1.0 0.00039 19.4 0.1 1.6 2 0 0 2 2 2 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAN10331.1 - 0.00082 18.3 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAN10331.1 - 0.018 14.5 0.2 0.036 13.6 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.11 GAN10331.1 - 0.043 13.7 0.2 0.17 11.8 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 GAN10331.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.16 GAN10332.1 - 1.2e-12 47.4 41.1 1.2e-12 47.4 41.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 GAN10332.1 - 3.5e-12 46.3 7.9 3.5e-12 46.3 7.9 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PspC PF04024.12 GAN10332.1 - 1.1 9.1 5.5 0.44 10.4 0.6 2.8 3 0 0 3 3 3 0 PspC domain bZIP_1 PF00170.21 GAN10333.1 - 4.6e-08 33.0 10.7 1e-06 28.7 10.7 2.6 1 1 0 1 1 1 1 bZIP transcription factor Ras PF00071.22 GAN10334.1 - 8.9e-58 194.5 0.4 1.6e-57 193.6 0.4 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN10334.1 - 1.4e-36 125.3 0.1 3.2e-36 124.2 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SurE PF01975.17 GAN10334.1 - 1.7e-26 93.2 0.0 3.2e-25 89.0 0.0 2.3 1 1 0 1 1 1 1 Survival protein SurE Arf PF00025.21 GAN10334.1 - 2.2e-15 56.5 0.2 3.4e-15 55.9 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAN10334.1 - 1.2e-06 28.0 0.3 2.2e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAN10334.1 - 1.7e-05 24.4 0.1 6.7e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN10334.1 - 2.2e-05 24.4 0.0 0.039 13.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAN10334.1 - 0.00011 22.2 0.0 0.00034 20.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN10334.1 - 0.0002 20.8 0.4 0.00041 19.8 0.4 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAN10334.1 - 0.0026 17.3 0.1 0.11 12.0 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Pkinase PF00069.25 GAN10335.1 - 4.4e-62 209.8 0.0 5.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10335.1 - 1.9e-40 138.8 0.0 2.5e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN10335.1 - 0.00035 20.0 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GST_N_4 PF17172.4 GAN10336.1 - 0.035 14.8 0.1 0.18 12.6 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain DUF287 PF03384.14 GAN10336.1 - 0.15 12.5 0.7 0.42 11.1 0.1 2.0 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 DUF3869 PF12985.7 GAN10338.1 - 0.15 12.4 0.3 4.6 7.7 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3869) Rabaptin PF03528.15 GAN10338.1 - 1.1 7.9 3.1 1.7 7.3 3.1 1.2 1 0 0 1 1 1 0 Rabaptin CIAPIN1 PF05093.13 GAN10339.1 - 2e-27 95.6 5.2 5.9e-27 94.1 5.2 1.8 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 PF08241.12 GAN10339.1 - 0.033 14.8 0.0 0.085 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAN10339.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2046 PF09755.9 GAN10340.1 - 9.4e-32 110.4 26.3 9.4e-32 110.4 26.3 1.9 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) fn3_5 PF06280.12 GAN10340.1 - 0.057 14.1 1.0 4.2 8.1 0.2 2.4 2 0 0 2 2 2 0 Fn3-like domain TSC22 PF01166.18 GAN10340.1 - 0.061 13.6 0.1 0.061 13.6 0.1 5.0 4 1 1 5 5 5 0 TSC-22/dip/bun family LIM PF00412.22 GAN10341.1 - 4.9e-10 39.5 7.5 5.4e-10 39.3 7.5 1.1 1 0 0 1 1 1 1 LIM domain DUF4468 PF14730.6 GAN10341.1 - 0.0074 16.6 0.2 0.0088 16.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4468) with TBP-like fold Nramp PF01566.18 GAN10342.1 - 2.3e-105 352.5 19.7 2.3e-105 352.5 19.7 1.6 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Ribosomal_L24e PF01246.20 GAN10343.1 - 4.2e-25 87.7 0.6 6.8e-25 87.1 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L24e V-ATPase_H_N PF03224.14 GAN10345.1 - 9.8e-78 261.6 1.1 1.2e-77 261.3 1.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H DUF2985 PF11204.8 GAN10345.1 - 0.00095 19.3 0.3 0.0027 17.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Arm PF00514.23 GAN10345.1 - 0.047 13.7 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF4745 PF15923.5 GAN10345.1 - 0.33 10.9 1.8 0.61 10.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) V-ATPase_H_C PF11698.8 GAN10346.1 - 1.6e-34 118.5 0.3 1.8e-34 118.4 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.6 GAN10346.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.4 1 1 0 1 1 1 1 HEAT repeats BAR PF03114.18 GAN10346.1 - 0.0013 18.4 0.3 0.0015 18.2 0.3 1.1 1 0 0 1 1 1 1 BAR domain KIAA1430 PF13879.6 GAN10346.1 - 0.0061 17.3 0.4 0.0069 17.1 0.4 1.2 1 1 0 1 1 1 1 KIAA1430 homologue DASH_Dad4 PF08650.10 GAN10346.1 - 0.087 12.8 0.7 0.2 11.7 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad4 Aminotran_1_2 PF00155.21 GAN10347.1 - 9.3e-44 150.1 0.0 1.1e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NDUF_B12 PF08122.12 GAN10348.1 - 1.5e-24 85.7 0.6 1.8e-24 85.5 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Peptidase_C78 PF07910.13 GAN10349.1 - 6.1e-56 189.2 0.1 9.5e-56 188.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 PSD1 PF07587.11 GAN10349.1 - 0.016 14.7 0.1 0.1 12.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1553) Microtub_bind PF13931.6 GAN10349.1 - 0.72 10.2 6.2 0.39 11.1 0.2 2.4 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding AcetylCoA_hydro PF02550.15 GAN10350.1 - 1.5e-50 172.0 0.0 2.2e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 GAN10350.1 - 2.2e-40 138.1 0.0 3.3e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AA_permease_2 PF13520.6 GAN10351.1 - 1.5e-58 198.7 58.8 1.9e-58 198.3 58.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN10351.1 - 2.1e-27 95.9 46.1 2.8e-27 95.4 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 GAN10352.1 - 2.7e-66 223.6 0.5 3.8e-66 223.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10352.1 - 3.8e-30 105.0 0.0 6.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN10352.1 - 8.1e-09 35.2 0.0 4e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAN10352.1 - 6.4e-05 22.4 0.1 0.00019 20.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAN10352.1 - 0.00016 20.6 0.4 0.00055 18.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase SUIM_assoc PF16619.5 GAN10352.1 - 0.0075 16.3 1.3 0.016 15.2 1.3 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 APH PF01636.23 GAN10352.1 - 0.022 14.7 0.1 0.022 14.7 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAN10352.1 - 0.035 13.6 0.0 0.035 13.6 0.0 2.4 3 1 0 3 3 3 0 PhoP regulatory network protein YrbL TetR_C_27 PF17935.1 GAN10352.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pantoate_transf PF02548.15 GAN10353.1 - 1.4e-110 368.8 0.3 1.6e-110 368.6 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 GAN10353.1 - 0.0084 15.6 0.3 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase CIAPIN1 PF05093.13 GAN10354.1 - 1.5e-30 105.6 4.5 4e-30 104.3 4.5 1.7 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1952 PF09189.10 GAN10354.1 - 0.018 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) Hist_deacetyl PF00850.19 GAN10355.1 - 3.5e-81 273.0 0.0 5e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MBT PF02820.18 GAN10355.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 mbt repeat Aminotran_4 PF01063.19 GAN10356.1 - 5.8e-32 111.4 0.0 7.3e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Cut8 PF08559.10 GAN10357.1 - 1.2e-50 172.4 0.1 1.4e-50 172.1 0.1 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Pkinase PF00069.25 GAN10358.1 - 2.1e-61 207.6 0.7 5e-53 180.1 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10358.1 - 2e-35 122.3 0.0 4.8e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN10358.1 - 9.3e-06 25.2 0.0 2.5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAN10358.1 - 0.076 12.9 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_7 PF13499.6 GAN10358.1 - 0.1 13.0 0.6 0.54 10.7 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain pair Kdo PF06293.14 GAN10358.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0154 PF03672.13 GAN10358.1 - 0.17 11.9 2.8 4.7 7.3 0.3 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) CENP-N PF05238.13 GAN10359.1 - 1.4e-23 83.9 0.1 3e-23 82.8 0.0 1.7 1 1 1 2 2 2 1 Kinetochore protein CHL4 like CENP-L PF13092.6 GAN10359.1 - 0.057 13.6 0.0 0.46 10.7 0.0 2.4 2 1 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 DUF4611 PF15387.6 GAN10359.1 - 0.058 13.6 4.3 0.1 12.8 3.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) MRP_L53 PF10780.9 GAN10360.1 - 2.4e-12 46.8 0.1 5.5e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 POLO_box PF00659.18 GAN10360.1 - 0.095 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 POLO box duplicated region CbtB PF09489.10 GAN10361.1 - 0.21 11.7 0.6 0.75 9.9 0.1 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) F-box-like PF12937.7 GAN10362.1 - 0.00032 20.5 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like CsbD PF05532.12 GAN10363.1 - 6.3e-06 26.0 0.2 0.011 15.6 0.9 2.3 2 0 0 2 2 2 2 CsbD-like Med21 PF11221.8 GAN10363.1 - 0.014 15.7 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Met_synt_B12 PF02965.17 GAN10364.1 - 7.7e-122 406.0 0.0 1.4e-121 405.1 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 GAN10364.1 - 7.6e-76 255.5 0.0 1.6e-75 254.4 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 GAN10364.1 - 7.3e-56 189.6 0.2 1.9e-55 188.2 0.2 1.8 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 GAN10364.1 - 7e-23 80.9 0.3 6.5e-22 77.8 0.1 2.9 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 GAN10364.1 - 4.9e-18 65.3 0.5 3.6e-17 62.5 0.3 2.5 2 0 0 2 2 2 1 B12 binding domain SKG6 PF08693.10 GAN10365.1 - 0.2 11.1 5.0 0.23 10.9 0.3 3.2 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Fasciclin PF02469.22 GAN10366.1 - 1.1e-24 87.0 0.2 2e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Glyoxal_oxid_N PF07250.11 GAN10367.1 - 6.8e-59 199.0 0.0 3.9e-58 196.5 0.0 2.1 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAN10367.1 - 3e-22 78.7 0.0 6e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 GAN10367.1 - 0.0062 16.5 2.8 11 6.1 0.0 4.5 4 1 1 5 5 5 2 Galactose oxidase, central domain Solute_trans_a PF03619.16 GAN10368.1 - 8.1e-52 176.4 10.3 9.8e-52 176.1 10.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BTB PF00651.31 GAN10369.1 - 0.0089 16.2 0.5 1.8 8.8 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain PC-Esterase PF13839.6 GAN10370.1 - 2.9e-25 89.6 0.0 5.7e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 GAN10370.1 - 3.1 8.2 7.8 0.56 10.6 3.1 2.2 2 0 0 2 2 2 0 PMR5 N terminal Domain Phosphodiest PF01663.22 GAN10371.1 - 6.7e-83 279.2 5.0 9.4e-83 278.7 5.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAN10371.1 - 1.1e-06 28.3 2.8 4.8e-05 22.9 1.6 3.0 2 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 GAN10371.1 - 4.4e-06 26.2 0.0 7.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphoesterase PF04185.14 GAN10371.1 - 0.038 13.2 0.3 0.085 12.0 0.2 1.6 1 1 0 1 1 1 0 Phosphoesterase family PglZ PF08665.12 GAN10371.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 PglZ domain DUF2615 PF11027.8 GAN10372.1 - 0.2 11.8 0.0 0.2 11.8 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2615) Dickkopf_N PF04706.12 GAN10372.1 - 0.27 11.7 10.0 0.84 10.2 10.0 1.8 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Mg_trans_NIPA PF05653.14 GAN10373.1 - 3.3e-98 328.4 25.7 4.4e-98 328.0 25.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAN10373.1 - 5.1e-06 26.7 5.6 5.1e-06 26.7 5.6 3.8 3 1 0 3 3 3 2 EamA-like transporter family Cofilin_ADF PF00241.20 GAN10374.1 - 1.1e-10 41.4 0.0 4.2e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 GAN10374.1 - 0.00057 20.4 0.0 0.0031 18.0 0.0 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAN10374.1 - 0.048 14.1 3.2 0.098 13.1 0.0 2.7 2 1 1 3 3 3 0 Pleckstrin homology domain TPP_enzyme_N PF02776.18 GAN10375.1 - 6.2e-50 169.2 0.2 3.8e-48 163.4 0.0 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAN10375.1 - 4.6e-41 139.8 0.0 9.4e-41 138.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAN10375.1 - 4.7e-25 88.2 0.1 2.3e-24 85.9 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Radical_SAM PF04055.21 GAN10375.1 - 0.0047 17.3 0.0 0.026 14.9 0.0 2.2 3 0 0 3 3 3 1 Radical SAM superfamily DXP_synthase_N PF13292.6 GAN10375.1 - 0.0078 15.5 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase PNTB PF02233.16 GAN10375.1 - 0.02 13.8 1.3 0.041 12.8 0.1 2.0 3 0 0 3 3 3 0 NAD(P) transhydrogenase beta subunit CO_dh PF02552.16 GAN10375.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Mito_fiss_Elm1 PF06258.11 GAN10376.1 - 5.2e-28 98.1 0.0 7.3e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Glyco_hydro_18 PF00704.28 GAN10377.1 - 1.5e-57 195.7 0.1 1.9e-57 195.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MRP-L46 PF11788.8 GAN10378.1 - 3.7e-20 72.8 5.3 7e-20 72.0 5.3 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 GAN10378.1 - 1.5e-07 31.5 0.3 3.1e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain LPP20 PF02169.16 GAN10378.1 - 0.018 15.4 2.5 0.034 14.5 2.5 1.5 1 0 0 1 1 1 0 LPP20 lipoprotein Tcp11 PF05794.13 GAN10378.1 - 0.48 9.5 6.5 2.7 7.0 6.3 1.9 1 1 0 1 1 1 0 T-complex protein 11 JTB PF05439.12 GAN10379.1 - 0.034 14.2 1.7 0.29 11.2 0.1 2.7 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) Tropomyosin_1 PF12718.7 GAN10379.1 - 0.058 13.5 18.0 0.23 11.6 4.1 2.9 2 1 0 2 2 2 0 Tropomyosin like GRIM-19 PF06212.12 GAN10379.1 - 0.084 12.8 1.7 0.25 11.3 1.7 1.8 1 0 0 1 1 1 0 GRIM-19 protein Phage_GP20 PF06810.11 GAN10379.1 - 0.16 11.7 8.2 0.073 12.9 2.0 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF948 PF06103.11 GAN10379.1 - 0.66 10.3 3.7 5.1 7.4 0.3 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.21 GAN10379.1 - 0.83 10.2 11.3 0.38 11.2 3.2 2.7 2 0 0 2 2 2 0 Spectrin repeat SpecificRecomb PF10136.9 GAN10379.1 - 1.6 6.9 9.7 1.8 6.7 8.8 1.5 1 1 0 1 1 1 0 Site-specific recombinase DUF724 PF05266.14 GAN10379.1 - 1.8 8.4 14.8 4.4 7.1 4.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 GAN10379.1 - 1.8 8.8 15.1 0.059 13.6 2.1 3.1 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.6 GAN10379.1 - 2.5 8.5 12.6 0.35 11.2 5.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mvb12 PF09452.10 GAN10379.1 - 4.3 7.8 7.9 14 6.2 0.1 3.5 3 1 1 4 4 4 0 ESCRT-I subunit Mvb12 YabA PF06156.13 GAN10379.1 - 4.7 7.9 14.9 11 6.8 0.9 3.3 2 1 0 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 GAN10379.1 - 5.2 7.4 23.0 0.032 14.6 4.9 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 GAN10379.1 - 6.2 7.4 20.4 7 7.2 3.8 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 GAN10379.1 - 6.3 5.6 22.5 8.2 5.2 17.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Peroxin-13_N PF04088.13 GAN10380.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region TRAP_alpha PF03896.16 GAN10382.1 - 3.6e-13 49.4 0.1 6e-13 48.7 0.1 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Robl_LC7 PF03259.17 GAN10382.1 - 1.7e-08 34.1 0.0 5.7e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Roadblock/LC7 domain FtsH_ext PF06480.15 GAN10382.1 - 0.0017 18.7 1.2 1 9.8 0.0 2.5 1 1 1 2 2 2 2 FtsH Extracellular DUF5305 PF17231.2 GAN10382.1 - 0.0079 15.6 0.1 0.022 14.2 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Sugar_tr PF00083.24 GAN10383.1 - 5.4e-25 88.2 0.9 1.2e-23 83.8 0.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter HEAT PF02985.22 GAN10385.1 - 5e-15 54.3 1.9 0.00013 21.9 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 GAN10385.1 - 4.9e-10 39.7 2.8 3.8e-06 27.3 0.0 4.9 6 0 0 6 6 5 2 HEAT-like repeat IBN_N PF03810.19 GAN10385.1 - 8.5e-09 35.2 2.1 6.9e-07 29.1 0.4 3.9 3 1 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 GAN10385.1 - 4.8e-08 33.3 0.0 0.00016 22.0 0.0 4.5 2 1 2 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 GAN10385.1 - 6e-06 26.8 0.0 0.0012 19.4 0.0 4.2 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 GAN10385.1 - 2.1e-05 23.3 3.3 0.0041 15.7 0.0 2.8 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GAN10385.1 - 0.00013 22.0 0.0 0.45 10.6 0.0 3.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 GAN10385.1 - 0.00016 20.9 4.1 0.00036 19.8 0.1 3.1 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Arm PF00514.23 GAN10385.1 - 0.0005 20.0 0.2 3.7 7.7 0.1 4.9 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 GAN10385.1 - 0.0013 18.4 3.6 0.037 13.6 0.0 4.1 3 1 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 GAN10385.1 - 0.007 16.5 0.0 0.42 10.8 0.0 3.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 GAN10385.1 - 0.013 15.2 1.1 0.087 12.5 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) Bromodomain PF00439.25 GAN10386.1 - 7.1e-18 64.5 0.9 1.9e-17 63.1 0.9 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GAN10386.1 - 0.00011 22.4 0.0 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN10386.1 - 0.00044 20.2 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN10386.1 - 0.0058 17.0 0.2 0.011 16.2 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain malic PF00390.19 GAN10386.1 - 0.072 12.9 0.3 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain GNAT_acetyltr_2 PF13718.6 GAN10386.1 - 0.19 11.1 0.0 0.19 11.1 0.0 3.8 3 1 0 3 3 3 0 GNAT acetyltransferase 2 Transthyretin PF00576.21 GAN10387.1 - 4.6e-37 127.1 0.0 5.4e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Complex1_LYR PF05347.15 GAN10388.1 - 1.4e-12 47.5 0.7 2.1e-12 46.9 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAN10388.1 - 0.0046 17.7 0.7 0.0066 17.2 0.7 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Chromo PF00385.24 GAN10390.1 - 9.5e-15 54.3 4.0 1.4e-13 50.5 1.2 2.4 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 GAN10390.1 - 3e-11 43.2 1.4 5e-09 36.1 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain PP2C_C PF07830.13 GAN10390.1 - 0.093 13.2 2.1 0.39 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DEAD PF00270.29 GAN10391.1 - 6.8e-50 169.3 0.0 2.9e-49 167.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN10391.1 - 1.7e-29 102.4 0.0 4.7e-28 97.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAN10391.1 - 0.0083 15.4 0.0 0.0083 15.4 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase TAF4 PF05236.14 GAN10391.1 - 0.017 14.9 9.6 0.027 14.2 9.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AAA_19 PF13245.6 GAN10391.1 - 0.052 13.9 0.2 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain CMS1 PF14617.6 GAN10391.1 - 0.063 12.6 14.8 0.66 9.3 0.0 3.1 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit DUF2529 PF10740.9 GAN10391.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DUF2009 PF09418.10 GAN10392.1 - 1e-210 700.6 0.0 1.3e-210 700.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 GAN10392.1 - 0.00012 22.2 5.3 0.00026 21.1 5.3 1.6 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 GAN10392.1 - 0.0013 19.0 3.0 0.0034 17.6 3.0 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 GAN10392.1 - 0.05 13.5 4.4 0.1 12.5 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1694 PF07997.11 GAN10392.1 - 0.36 10.9 2.0 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) ABC_membrane PF00664.23 GAN10393.1 - 2e-59 201.5 30.7 5.7e-34 118.0 11.9 3.4 3 1 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 GAN10393.1 - 5.3e-51 172.7 0.0 4.1e-29 101.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAN10393.1 - 1.8e-08 34.1 10.5 0.0009 18.7 2.8 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 GAN10393.1 - 2e-06 27.1 0.0 0.0046 16.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_24 PF13479.6 GAN10393.1 - 5.1e-06 26.3 0.3 0.002 17.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAN10393.1 - 1.6e-05 24.6 1.3 0.062 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN10393.1 - 0.00013 22.2 0.0 0.73 10.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 GAN10393.1 - 0.00017 21.6 0.5 0.27 11.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 GAN10393.1 - 0.00018 20.9 0.2 0.068 12.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 GAN10393.1 - 0.00025 21.0 0.6 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 GAN10393.1 - 0.0014 18.5 0.4 1.4 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAN10393.1 - 0.0021 18.4 0.1 4.2 7.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 GAN10393.1 - 0.0025 17.6 0.3 6.3 6.5 0.0 3.7 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 GAN10393.1 - 0.0027 17.2 0.1 1.7 8.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 GAN10393.1 - 0.0032 17.6 0.1 0.0032 17.6 0.1 3.0 4 0 0 4 4 2 1 Dynamin family AAA_23 PF13476.6 GAN10393.1 - 0.0037 17.8 0.1 0.0037 17.8 0.1 4.5 5 0 0 5 5 4 1 AAA domain DUF87 PF01935.17 GAN10393.1 - 0.0046 17.1 2.4 0.46 10.5 0.4 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 GAN10393.1 - 0.0076 15.8 0.1 2.6 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 GAN10393.1 - 0.024 14.4 1.8 9.7 5.9 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAN10393.1 - 0.027 14.9 0.1 5.6 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 GAN10393.1 - 0.036 14.2 0.1 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAN10393.1 - 0.039 14.5 0.1 6 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAN10393.1 - 0.067 12.9 0.1 16 5.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 GAN10393.1 - 0.13 11.6 0.0 7 5.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 GAN10393.1 - 0.2 11.3 11.5 1.2 8.8 0.0 3.6 4 0 0 4 4 4 0 AAA ATPase domain ATPase PF06745.13 GAN10393.1 - 0.33 10.3 2.3 6.6 6.0 0.0 2.7 3 0 0 3 3 3 0 KaiC Cytomega_UL84 PF06284.11 GAN10393.1 - 0.36 9.2 0.0 0.36 9.2 0.0 1.6 2 0 0 2 2 1 0 Cytomegalovirus UL84 protein NACHT PF05729.12 GAN10393.1 - 0.88 9.5 2.7 33 4.3 0.0 3.2 3 0 0 3 3 3 0 NACHT domain DUF3134 PF11332.8 GAN10393.1 - 8.5 6.8 12.1 1.7 9.0 6.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) E1-E2_ATPase PF00122.20 GAN10394.1 - 1.3e-44 151.9 5.2 1.3e-44 151.9 5.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAN10394.1 - 1.5e-22 81.0 0.3 3.1e-22 79.9 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAN10394.1 - 0.0037 17.0 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAN10394.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAN10395.1 - 3.6e-07 29.8 0.0 6.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus AAA_18 PF13238.6 GAN10395.1 - 0.097 13.2 0.0 0.1 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain PH PF00169.29 GAN10397.1 - 1.9e-07 31.5 5.2 5.6e-07 30.0 0.2 3.3 3 1 0 3 3 3 1 PH domain Adaptin_N PF01602.20 GAN10398.1 - 3.2e-139 464.8 9.5 4.1e-139 464.5 9.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAN10398.1 - 8e-21 74.7 3.2 8.7e-20 71.4 0.0 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAN10398.1 - 4.1e-07 30.3 7.1 0.0068 16.8 0.0 4.8 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAN10398.1 - 0.00024 21.1 5.8 0.2 12.0 0.0 6.5 8 1 1 9 9 9 1 HEAT repeat Cohesin_HEAT PF12765.7 GAN10398.1 - 0.011 16.1 0.1 0.041 14.2 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion SDA1 PF05285.12 GAN10398.1 - 0.8 9.1 21.9 2 7.8 21.9 1.6 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GAN10398.1 - 1.6 8.5 9.8 2.8 7.7 9.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GAN10398.1 - 3.2 5.9 24.7 5.8 5.0 24.7 1.4 1 0 0 1 1 1 0 Nop14-like family Sec16_C PF12931.7 GAN10399.1 - 1.8e-88 297.1 0.0 3.8e-88 296.0 0.0 1.6 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 GAN10399.1 - 8e-27 94.2 0.2 4.4e-26 91.8 0.0 2.5 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region DZR PF12773.7 GAN10399.1 - 0.0025 17.8 0.8 0.0056 16.7 0.8 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 GAN10399.1 - 0.033 13.9 2.2 0.068 12.9 2.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF5560 PF17715.1 GAN10399.1 - 7.5 6.0 10.4 0.057 12.9 1.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5560) Peptidase_M13 PF01431.21 GAN10400.1 - 1.3e-55 188.2 0.2 4.5e-55 186.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 GAN10400.1 - 2.8e-43 149.1 2.3 5e-43 148.2 2.3 1.3 1 0 0 1 1 1 1 Peptidase family M13 HEPN_Swt1 PF18731.1 GAN10400.1 - 0.027 14.8 0.2 3.7 7.9 0.0 3.0 2 0 0 2 2 2 0 Swt1-like HEPN APOC4 PF15119.6 GAN10400.1 - 0.67 10.2 2.5 26 5.1 0.0 4.1 5 0 0 5 5 5 0 Apolipoprotein C4 MFS_1 PF07690.16 GAN10401.1 - 3.6e-12 45.9 42.6 3.6e-12 45.9 42.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 GAN10401.1 - 1.8e-11 44.0 9.8 1.8e-11 44.0 9.8 2.7 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 bZIP_1 PF00170.21 GAN10402.1 - 6.9e-08 32.5 11.1 1.1e-06 28.7 11.1 2.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN10402.1 - 0.0018 18.3 11.5 0.0091 16.1 6.9 3.0 2 0 0 2 2 2 1 Basic region leucine zipper CDC45 PF02724.14 GAN10402.1 - 0.77 8.0 6.6 1.2 7.3 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein zinc_ribbon_9 PF14369.6 GAN10403.1 - 0.041 14.1 2.9 0.12 12.6 2.9 1.9 1 0 0 1 1 1 0 zinc-ribbon PHM7_cyt PF14703.6 GAN10403.1 - 0.042 14.1 0.2 0.089 13.0 0.2 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Zn-ribbon_8 PF09723.10 GAN10403.1 - 0.14 12.3 1.1 0.46 10.6 1.1 2.0 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 GAN10403.1 - 1 9.4 4.6 0.61 10.2 1.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon RGS PF00615.19 GAN10405.1 - 1.1e-09 38.6 0.0 2.5e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain PGM_PMM_I PF02878.16 GAN10406.1 - 8.4e-36 122.7 0.1 1.4e-35 122.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAN10406.1 - 2.2e-29 101.9 0.0 4.6e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAN10406.1 - 6.3e-16 58.9 0.1 1.6e-15 57.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAN10406.1 - 8e-09 35.6 0.0 2.8e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Autophagy_N PF03986.13 GAN10407.1 - 4.4e-45 153.0 4.0 8.4e-45 152.1 4.0 1.5 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 GAN10407.1 - 6e-20 71.6 0.5 1.7e-19 70.2 0.5 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 GAN10407.1 - 6.2e-16 57.6 3.6 1.1e-15 56.8 3.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CDC27 PF09507.10 GAN10407.1 - 1.3 8.3 8.7 1.9 7.8 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Malic_M PF03949.15 GAN10408.1 - 4.5e-82 275.2 0.2 6.2e-82 274.7 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAN10408.1 - 7.7e-57 192.0 0.0 1.7e-56 190.9 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PadR PF03551.14 GAN10408.1 - 0.094 12.7 0.2 0.67 10.0 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family PDEase_I PF00233.19 GAN10409.1 - 2.2e-72 243.7 1.3 3.4e-71 239.7 1.3 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 GAN10409.1 - 0.0011 19.2 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 HD domain Asp PF00026.23 GAN10410.1 - 1.5e-30 106.7 0.0 2.6e-24 86.2 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN10410.1 - 4.1e-07 30.4 0.1 0.0011 19.2 0.0 4.5 3 3 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAN10410.1 - 0.038 14.6 0.0 17 6.2 0.0 3.5 3 1 0 3 3 3 0 Aspartyl protease Pkinase PF00069.25 GAN10411.1 - 5.8e-72 242.2 0.2 5.8e-72 242.2 0.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10411.1 - 4.3e-51 173.7 0.2 4.3e-51 173.7 0.2 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 GAN10411.1 - 4.5e-20 71.7 0.0 2.2e-19 69.6 0.0 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 GAN10411.1 - 6.3e-12 45.9 0.5 1.8e-11 44.5 0.5 1.8 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 GAN10411.1 - 1.3e-07 30.8 0.0 1.3e-07 30.8 0.0 2.4 2 1 0 2 2 1 1 Fungal protein kinase Kinase-like PF14531.6 GAN10411.1 - 6.3e-07 29.0 0.1 3.7e-06 26.5 0.1 2.2 1 1 1 2 2 2 1 Kinase-like PH_11 PF15413.6 GAN10411.1 - 0.0014 19.0 3.5 0.16 12.4 0.0 3.5 2 1 1 3 3 3 1 Pleckstrin homology domain Haspin_kinase PF12330.8 GAN10411.1 - 0.0015 17.5 7.7 0.0042 16.1 7.7 1.8 1 1 0 1 1 1 1 Haspin like kinase domain PH_9 PF15410.6 GAN10411.1 - 0.029 14.7 1.4 16 5.9 0.0 3.8 2 1 1 3 3 3 0 Pleckstrin homology domain Apis_Csd PF11671.8 GAN10411.1 - 0.03 14.3 9.5 0.064 13.3 9.5 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein Seadorna_VP7 PF07387.11 GAN10411.1 - 0.049 12.7 0.3 0.12 11.4 0.3 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 GAN10411.1 - 0.13 12.2 6.4 0.28 11.0 0.3 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family TFIIA PF03153.13 GAN10411.1 - 0.26 11.3 31.7 0.39 10.7 31.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 GAN10411.1 - 0.6 9.6 14.4 1 8.8 14.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 GAN10411.1 - 1.2 9.5 16.2 7.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Androgen_recep PF02166.16 GAN10411.1 - 9.9 4.9 23.7 0.53 9.1 4.2 2.2 2 0 0 2 2 2 0 Androgen receptor Kelch_4 PF13418.6 GAN10412.1 - 2.6e-24 85.0 5.0 4.3e-09 36.2 0.2 5.5 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN10412.1 - 8.2e-23 79.9 5.6 0.00018 21.7 0.1 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 GAN10412.1 - 9.4e-23 79.3 6.9 7.7e-05 22.5 0.1 5.9 5 1 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 GAN10412.1 - 5.8e-21 74.1 4.9 1.4e-05 24.9 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 GAN10412.1 - 1.2e-20 72.8 6.1 2.5e-05 23.8 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 GAN10412.1 - 5.6e-19 67.9 3.5 0.0028 17.9 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 GAN10412.1 - 3.2e-13 49.9 0.0 8.5e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Coat_X PF07552.11 GAN10412.1 - 0.66 9.8 6.5 0.18 11.7 1.9 2.3 3 0 0 3 3 3 0 Spore Coat Protein X and V domain Amelogenin PF02948.15 GAN10413.1 - 0.0074 17.0 0.5 0.0081 16.8 0.5 1.1 1 0 0 1 1 1 1 Amelogenin GPP34 PF05719.11 GAN10414.1 - 7e-63 212.3 0.0 9.1e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Diphthamide_syn PF01866.17 GAN10415.1 - 2.2e-103 345.9 4.7 2.3e-102 342.5 4.7 1.9 1 1 0 1 1 1 1 Putative diphthamide synthesis protein CTU2 PF10288.9 GAN10415.1 - 0.0041 17.4 0.1 0.0093 16.2 0.1 1.5 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 RNB PF00773.19 GAN10416.1 - 1.5e-101 340.0 0.0 2.1e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAN10416.1 - 1.5e-20 73.0 0.0 3.8e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 GAN10416.1 - 8.4e-14 51.5 0.0 2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 GAN10416.1 - 6.5e-12 45.9 0.2 1.6e-11 44.6 0.2 1.7 1 0 0 1 1 1 1 PIN domain Rrp44_S1 PF17215.3 GAN10416.1 - 7.6e-12 45.0 0.1 2e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 GAN10416.1 - 3.8e-09 36.6 0.2 5.9e-07 29.6 0.0 3.7 4 0 0 4 4 4 1 Cold shock domain Dis3l2_C_term PF17877.1 GAN10416.1 - 0.12 12.7 0.1 0.41 11.0 0.1 1.9 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal DUF3659 PF12396.8 GAN10417.1 - 7.1e-114 371.8 79.8 8.6e-18 64.0 5.8 9.8 10 0 0 10 10 10 9 Protein of unknown function (DUF3659) DUF883 PF05957.13 GAN10417.1 - 4.4 8.0 61.5 0.085 13.5 11.8 5.8 4 1 1 6 6 6 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 GAN10418.1 - 0.45 11.1 12.9 4.2 8.0 3.5 2.7 2 0 0 2 2 2 0 YtxH-like protein AAA_32 PF13654.6 GAN10418.1 - 2.7 6.7 13.6 11 4.6 13.4 2.1 1 1 0 1 1 1 0 AAA domain DUF3810 PF12725.7 GAN10418.1 - 6.2 6.1 8.8 3.1e+02 0.5 8.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) SUFU_C PF12470.8 GAN10419.1 - 0.39 10.7 8.3 0.44 10.6 8.3 1.0 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain GET2 PF08690.10 GAN10419.1 - 1.3 8.6 12.9 1.4 8.5 12.9 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 SOBP PF15279.6 GAN10419.1 - 1.5 9.3 11.1 1.6 9.3 11.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein eIF3_subunit PF08597.10 GAN10419.1 - 2.2 8.1 17.6 2.3 8.1 17.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MDM10 PF12519.8 GAN10419.1 - 2.5 6.9 11.5 2.7 6.7 11.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 YqfQ PF14181.6 GAN10419.1 - 2.9 8.1 13.8 3.3 7.9 13.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein DDHD PF02862.17 GAN10419.1 - 4.3 7.4 11.1 4.9 7.2 11.1 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 GAN10419.1 - 5.5 5.2 13.9 5.5 5.1 13.9 1.0 1 0 0 1 1 1 0 CDC45-like protein BORG_CEP PF14957.6 GAN10419.1 - 6.3 8.0 13.6 7.7 7.7 13.6 1.1 1 0 0 1 1 1 0 Cdc42 effector Asp-B-Hydro_N PF05279.11 GAN10419.1 - 7.1 6.6 12.0 7.4 6.6 12.0 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 GAN10419.1 - 8.1 5.1 15.9 8.5 5.0 15.9 1.0 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 GAN10419.1 - 9.4 5.0 10.8 9.5 5.0 10.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein GRP PF07172.11 GAN10420.1 - 0.033 14.9 7.1 0.047 14.4 7.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family RNA_pol_Rpc4 PF05132.14 GAN10420.1 - 1 9.8 7.5 1.2 9.5 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 GAN10421.1 - 0.13 10.4 37.8 0.16 10.1 37.8 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAN10421.1 - 2.9 6.1 25.7 3.7 5.7 25.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 GAN10421.1 - 3.7 7.2 27.2 4.6 6.9 27.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PNISR PF15996.5 GAN10421.1 - 5.5 7.2 25.4 6.7 6.9 25.4 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CNDH2_C PF16858.5 GAN10421.1 - 5.9 6.7 16.9 7.5 6.3 16.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Presenilin PF01080.17 GAN10421.1 - 6 5.5 15.2 7.1 5.3 15.2 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GAN10421.1 - 9.2 5.0 13.8 10 4.8 13.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 GAN10422.1 - 1.3 7.7 15.6 1.4 7.6 15.6 1.2 1 0 0 1 1 1 0 Presenilin Dsh_C PF12316.8 GAN10422.1 - 1.7 9.0 16.1 2.4 8.5 16.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Menin PF05053.13 GAN10422.1 - 2.3 6.5 14.2 2.4 6.4 14.2 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 GAN10422.1 - 2.4 6.6 22.1 2.9 6.4 22.1 1.0 1 0 0 1 1 1 0 Macoilin family SMYLE_N PF18615.1 GAN10422.1 - 7.1 6.1 14.9 8 5.9 14.9 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SOBP PF15279.6 GAN10422.1 - 8.3 6.9 20.4 9.7 6.7 20.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein CDC27 PF09507.10 GAN10422.1 - 9.7 5.5 42.8 11 5.2 42.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pkinase PF00069.25 GAN10423.1 - 1.3e-51 175.5 0.0 6.9e-39 133.8 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10423.1 - 1.8e-19 70.1 0.1 8e-12 45.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAN10423.1 - 2.1e-06 27.3 0.0 0.0017 17.7 0.0 2.8 2 1 1 3 3 3 2 Kinase-like FTA2 PF13095.6 GAN10423.1 - 0.044 13.4 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAN10423.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GDA1_CD39 PF01150.17 GAN10424.1 - 5.2e-102 341.7 0.0 7.4e-102 341.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 GAN10424.1 - 0.00056 19.4 0.1 0.0022 17.5 0.0 1.8 2 0 0 2 2 2 1 Ppx/GppA phosphatase family Fungal_trans PF04082.18 GAN10426.1 - 0.00031 19.9 1.4 0.00031 19.9 1.4 2.8 3 1 0 3 3 3 1 Fungal specific transcription factor domain DUF45 PF01863.17 GAN10426.1 - 0.12 12.4 2.9 0.29 11.2 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 COMPASS-Shg1 PF05205.12 GAN10426.1 - 3 8.6 10.7 1.1e+02 3.6 0.0 3.2 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 CotH PF08757.11 GAN10427.1 - 1.7e-35 123.1 2.0 3.1e-35 122.3 2.0 1.3 1 0 0 1 1 1 1 CotH kinase protein Colicin_im PF03857.13 GAN10427.1 - 0.073 13.0 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Colicin immunity protein DDE_3 PF13358.6 GAN10428.1 - 1.2e-14 54.3 0.0 1.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease BCAS2 PF05700.11 GAN10429.1 - 6.9e-66 221.9 14.1 8e-66 221.7 14.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DAO_C PF16901.5 GAN10429.1 - 0.059 13.2 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF5398 PF17376.2 GAN10429.1 - 0.16 12.6 0.1 0.16 12.6 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5398) SKA2 PF16740.5 GAN10429.1 - 1.1 9.1 9.4 0.083 12.7 3.8 2.1 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 2 MFS_1 PF07690.16 GAN10430.1 - 4.8e-16 58.6 38.9 1.3e-15 57.3 38.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAN10430.1 - 9.5e-06 24.4 16.3 9.5e-06 24.4 16.3 2.8 1 1 1 3 3 3 1 MFS/sugar transport protein Homeodomain PF00046.29 GAN10431.1 - 6.2e-07 29.2 1.2 1.4e-06 28.0 1.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN10431.1 - 0.008 16.1 1.3 0.014 15.3 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain RR_TM4-6 PF06459.12 GAN10431.1 - 0.14 11.9 5.8 0.23 11.3 5.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lipase_GDSL PF00657.22 GAN10432.1 - 2.6e-10 40.6 0.1 4.2e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN10432.1 - 3.9e-06 27.4 0.0 6.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Nmad2 PF18753.1 GAN10432.1 - 0.011 15.2 0.1 0.029 13.8 0.1 1.7 2 0 0 2 2 2 0 Nucleotide modification associated domain 2 DUF148 PF02520.17 GAN10432.1 - 0.41 10.8 6.6 1.5 9.0 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 Fib_alpha PF08702.10 GAN10432.1 - 0.96 9.6 4.6 1.2 9.4 0.3 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RCR PF12273.8 GAN10432.1 - 1.5 9.5 3.9 18 6.0 0.3 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Aa_trans PF01490.18 GAN10434.1 - 5.1e-74 249.4 29.5 8.5e-61 205.9 20.4 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein LSM PF01423.22 GAN10435.1 - 1.3e-20 72.9 0.1 1.4e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAN10435.1 - 7.8e-05 22.7 0.0 9.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 GAN10435.1 - 0.023 14.8 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain PI3K_rbd PF00794.18 GAN10435.1 - 0.094 12.9 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF150_C PF17384.2 GAN10435.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain ABC_membrane PF00664.23 GAN10436.1 - 2.4e-116 388.2 19.4 2.3e-60 204.6 6.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN10436.1 - 6.9e-69 230.7 5.0 2.7e-35 121.9 0.1 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAN10436.1 - 2.9e-13 49.8 7.3 1e-06 28.4 0.3 4.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GAN10436.1 - 4.7e-09 35.6 0.7 0.00058 18.8 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 GAN10436.1 - 1.9e-08 34.7 1.8 0.0036 17.6 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAN10436.1 - 2.1e-07 31.5 3.6 0.005 17.2 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 GAN10436.1 - 2e-06 27.7 3.6 0.065 12.9 0.0 4.3 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAN10436.1 - 4.3e-06 26.7 1.2 0.15 11.9 0.1 3.3 3 0 0 3 3 3 2 RsgA GTPase Rad17 PF03215.15 GAN10436.1 - 6.6e-06 26.2 0.6 0.018 15.0 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_29 PF13555.6 GAN10436.1 - 1.4e-05 24.8 1.3 0.084 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain G-alpha PF00503.20 GAN10436.1 - 3.1e-05 23.3 1.2 0.22 10.7 0.0 3.0 3 1 0 3 3 3 2 G-protein alpha subunit Zeta_toxin PF06414.12 GAN10436.1 - 7e-05 22.2 0.3 0.11 11.8 0.0 3.6 4 0 0 4 4 4 1 Zeta toxin AAA PF00004.29 GAN10436.1 - 9.1e-05 22.9 4.8 0.46 10.9 1.1 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 GAN10436.1 - 0.00021 21.4 5.5 0.2 11.9 0.7 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 GAN10436.1 - 0.00026 21.2 0.1 1.1 9.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 GAN10436.1 - 0.00076 19.0 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 GAN10436.1 - 0.0011 19.5 0.1 4.1 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 GAN10436.1 - 0.0012 19.3 3.4 8.4 6.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 GAN10436.1 - 0.002 18.4 0.1 2.1 8.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAN10436.1 - 0.0023 17.9 1.1 7.8 6.5 0.0 4.3 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 GAN10436.1 - 0.0032 17.2 0.0 0.22 11.2 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 GAN10436.1 - 0.005 16.6 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 GAN10436.1 - 0.0054 16.4 0.1 1 8.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 GAN10436.1 - 0.0085 16.5 0.1 5.6 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 GAN10436.1 - 0.013 14.7 0.0 0.5 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 GAN10436.1 - 0.015 15.1 0.1 33 4.2 0.0 4.0 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 GAN10436.1 - 0.016 15.1 0.1 0.74 9.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 GAN10436.1 - 0.029 14.1 0.1 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 GAN10436.1 - 0.031 13.9 0.7 13 5.3 0.1 3.4 3 0 0 3 3 3 0 AAA domain GMC_oxred_N PF00732.19 GAN10436.1 - 0.032 13.6 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase Mg_chelatase PF01078.21 GAN10436.1 - 0.037 13.4 0.1 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 GAN10436.1 - 0.075 12.2 1.2 10 5.2 0.5 3.1 2 1 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 GAN10436.1 - 0.1 12.7 0.1 21 5.2 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Usp PF00582.26 GAN10436.1 - 0.33 11.5 2.3 11 6.5 0.3 3.0 2 1 1 3 3 2 0 Universal stress protein family IstB_IS21 PF01695.17 GAN10436.1 - 0.92 9.2 3.3 26 4.5 0.1 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Metallophos PF00149.28 GAN10437.1 - 2.2e-17 64.2 1.9 4.7e-17 63.2 1.9 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAN10437.1 - 1.8e-05 25.0 0.1 7.3e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SPRY PF00622.28 GAN10438.1 - 5.8e-22 78.1 0.2 9.3e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 SPRY domain UBX PF00789.20 GAN10439.1 - 5.4e-18 65.0 0.2 6.3e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 GAN10439.1 - 4.4e-07 29.7 0.0 1.2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 GAN10439.1 - 0.39 11.1 2.6 0.61 10.4 0.1 2.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Borrelia_P83 PF05262.11 GAN10439.1 - 1.5 7.2 28.1 10 4.5 27.0 1.9 1 1 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 GAN10439.1 - 3.9 4.5 15.0 4.8 4.2 15.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DDRGK PF09756.9 GAN10439.1 - 3.9 7.0 33.7 0.13 11.8 14.1 2.2 1 1 1 2 2 2 0 DDRGK domain Hamartin PF04388.12 GAN10439.1 - 5.1 5.6 14.8 5.6 5.5 14.8 1.0 1 0 0 1 1 1 0 Hamartin protein MAJIN PF15077.6 GAN10439.1 - 6.5 6.5 14.9 11 5.8 14.9 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein PA26 PF04636.13 GAN10439.1 - 7.6 5.3 11.3 10 4.9 11.3 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) KAR9 PF08580.10 GAN10440.1 - 4e-13 48.8 26.6 2.1e-07 29.9 0.2 3.2 3 0 0 3 3 3 3 Yeast cortical protein KAR9 GAS2 PF02187.17 GAN10440.1 - 1.5e-06 28.2 0.1 0.0001 22.3 0.1 3.3 3 0 0 3 3 3 1 Growth-Arrest-Specific Protein 2 Domain SKA2 PF16740.5 GAN10440.1 - 0.001 18.9 0.3 0.0044 16.8 0.0 2.1 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF4795 PF16043.5 GAN10440.1 - 0.52 9.9 5.0 0.94 9.0 3.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) CPSase_L_D2 PF02786.17 GAN10441.1 - 2.9e-79 265.4 0.1 5.4e-79 264.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAN10441.1 - 6.7e-70 234.9 0.0 1.1e-69 234.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAN10441.1 - 4.3e-39 133.5 0.0 1e-38 132.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAN10441.1 - 1.2e-31 109.0 0.0 5.3e-31 106.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAN10441.1 - 1.2e-30 107.0 0.1 2.1e-30 106.2 0.1 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAN10441.1 - 1.1e-15 57.2 7.5 2.1e-15 56.3 3.0 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAN10441.1 - 1.1e-08 34.9 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAN10441.1 - 5.7e-07 29.3 0.1 1.2e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 GAN10441.1 - 3e-06 27.9 1.9 0.073 13.8 0.3 3.4 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 GAN10441.1 - 1.4e-05 24.8 2.2 0.0098 15.7 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 GAN10441.1 - 0.00015 21.8 0.0 0.00054 20.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 GAN10441.1 - 0.00025 20.4 1.0 0.032 13.4 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 GAN10441.1 - 0.00025 20.7 0.1 0.0014 18.3 0.1 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 GAN10441.1 - 0.0055 16.3 0.1 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 GAN10441.1 - 0.0061 15.9 0.0 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 GAN10441.1 - 0.08 12.8 0.3 0.25 11.3 0.3 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein SAC3_GANP PF03399.16 GAN10442.1 - 2.4e-100 335.7 8.1 2.4e-100 335.7 8.1 2.1 2 0 0 2 2 2 1 SAC3/GANP family TFIIA PF03153.13 GAN10442.1 - 1.8 8.4 54.5 0.17 11.8 18.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SIR2 PF02146.17 GAN10443.1 - 1.7e-62 210.5 0.0 2.6e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 GAN10443.1 - 0.00028 20.7 0.3 0.00064 19.5 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 GAN10443.1 - 0.029 14.1 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ASH PF15780.5 GAN10444.1 - 3.5e-15 56.0 3.5 0.0048 17.1 0.1 9.1 9 0 0 9 9 9 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 GAN10444.1 - 9.7e-08 32.2 8.5 2.1 8.6 0.0 7.9 6 1 2 8 8 8 2 Transmembrane protein 131-like DUF1573 PF07610.11 GAN10444.1 - 3.1e-05 23.9 2.3 6.1 6.9 0.0 6.9 7 0 0 7 7 7 1 Protein of unknown function (DUF1573) PapD-like PF14874.6 GAN10444.1 - 5.4e-05 23.3 0.0 0.38 10.9 0.0 4.2 4 0 0 4 4 4 2 Flagellar-associated PapD-like fn3_5 PF06280.12 GAN10444.1 - 0.036 14.8 16.5 10 6.9 0.2 6.8 6 0 0 6 6 6 0 Fn3-like domain DUF4981 PF16353.5 GAN10444.1 - 0.066 13.7 4.9 37 4.9 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function(DUF4981) Neur_chan_memb PF02932.16 GAN10444.1 - 0.38 10.8 9.3 0.061 13.4 2.4 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF5446 PF17522.2 GAN10444.1 - 3.5 7.9 16.0 0.12 12.5 2.9 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5446) Snapin_Pallidin PF14712.6 GAN10444.1 - 4.3 7.8 11.9 1.4 9.4 6.1 3.0 3 0 0 3 3 3 0 Snapin/Pallidin PCRF PF03462.18 GAN10444.1 - 7.8 6.3 10.1 0.57 10.0 4.6 2.0 2 0 0 2 2 2 0 PCRF domain DDHD PF02862.17 GAN10444.1 - 9 6.4 7.2 20 5.3 0.8 2.6 2 0 0 2 2 2 0 DDHD domain Polysacc_deac_1 PF01522.21 GAN10445.1 - 7e-22 77.6 0.2 1.5e-21 76.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase F-box-like PF12937.7 GAN10448.1 - 2.3e-05 24.2 0.0 7.1e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN10448.1 - 0.0033 17.8 0.4 10 6.7 0.2 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN10448.1 - 0.041 13.8 2.8 0.15 12.0 0.1 3.3 4 1 0 4 4 4 0 F-box domain PDZ_1 PF12812.7 GAN10449.1 - 2.4e-26 91.6 0.1 5.9e-18 64.7 0.0 2.9 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 GAN10449.1 - 2.2e-18 67.6 0.0 1.6e-14 55.1 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 GAN10449.1 - 1.4e-14 54.2 0.5 0.0013 19.0 0.0 4.8 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 GAN10449.1 - 4.5e-11 42.4 0.1 0.12 12.3 0.0 5.0 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 GAN10449.1 - 1.6e-07 31.6 0.1 1.8 9.0 0.0 4.7 4 0 0 4 4 4 3 PDZ domain Ribosomal_L27 PF01016.19 GAN10450.1 - 9.2e-39 131.3 1.4 1.2e-38 131.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein Ank_2 PF12796.7 GAN10451.1 - 4.9e-34 116.8 3.1 1.4e-14 54.4 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) DHHC PF01529.20 GAN10451.1 - 3.2e-33 114.7 10.7 3.2e-33 114.7 10.7 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 GAN10451.1 - 2.2e-27 95.0 8.1 8.1e-08 32.7 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAN10451.1 - 4.7e-24 83.7 5.7 8.5e-06 26.0 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 GAN10451.1 - 1.2e-23 82.8 1.4 4.4e-07 30.0 0.0 5.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN10451.1 - 4.5e-23 78.8 1.4 0.017 15.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat PIN_4 PF13638.6 GAN10452.1 - 1.5e-27 96.5 0.1 3.4e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 PIN domain DUF5613 PF18467.1 GAN10452.1 - 0.015 15.7 0.9 0.029 14.8 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) PH PF00169.29 GAN10453.1 - 6.7e-09 36.2 0.1 1.6e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 PH domain Imm17 PF15562.6 GAN10453.1 - 0.032 14.1 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 17 Homeodomain PF00046.29 GAN10454.1 - 2e-19 69.2 2.1 4.2e-19 68.1 2.1 1.6 1 0 0 1 1 1 1 Homeodomain Roughex PF06020.11 GAN10454.1 - 0.0051 16.0 1.4 0.0051 16.0 1.4 2.8 3 0 0 3 3 3 1 Drosophila roughex protein Homeobox_KN PF05920.11 GAN10454.1 - 0.12 12.3 0.6 0.42 10.6 0.6 2.0 1 0 0 1 1 1 0 Homeobox KN domain Alginate_lyase PF05426.12 GAN10456.1 - 1.7e-43 149.1 0.0 2.7e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Alginate lyase DUF2278 PF10042.9 GAN10456.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) TPT PF03151.16 GAN10457.1 - 4e-62 210.2 23.9 4.8e-62 209.9 23.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN10457.1 - 3.7e-17 62.8 29.0 1.8e-10 41.1 8.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAN10457.1 - 5.1e-10 39.0 24.6 6.7e-10 38.7 24.6 1.1 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 GAN10457.1 - 0.015 16.0 3.9 0.015 16.0 3.9 2.3 2 1 0 2 2 2 0 Small Multidrug Resistance protein HMG_box PF00505.19 GAN10458.1 - 5.5e-18 65.2 0.4 1.2e-17 64.1 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN10458.1 - 1.5e-07 31.9 0.4 3.2e-07 30.9 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain DUF5526 PF17664.1 GAN10458.1 - 0.17 11.4 1.7 1.9 8.0 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5526) AAA_12 PF13087.6 GAN10459.1 - 7e-39 133.5 0.0 1.3e-38 132.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAN10459.1 - 2.2e-26 93.2 1.6 6.5e-14 52.4 0.7 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAN10459.1 - 4.1e-10 40.2 0.0 2e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAN10459.1 - 2.5e-08 33.9 0.0 0.00028 20.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 GAN10459.1 - 0.0012 18.2 0.0 0.051 12.8 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GAN10459.1 - 0.0026 17.2 0.0 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 GAN10459.1 - 0.0084 16.1 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TetR_C_5 PF08360.11 GAN10459.1 - 0.1 12.8 0.5 16 5.7 0.0 2.6 2 0 0 2 2 2 0 QacR-like protein, C-terminal region AAA_22 PF13401.6 GAN10459.1 - 0.11 12.8 0.3 14 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 GAN10459.1 - 0.22 11.5 0.4 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAN10459.1 - 0.27 11.8 1.6 2.5 8.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 GAN10459.1 - 0.28 10.9 0.7 2.7 7.7 0.0 2.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 GAN10459.1 - 0.39 10.2 4.7 2.1 7.8 0.0 2.8 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Pyr_redox_2 PF07992.14 GAN10461.1 - 3.9e-64 216.7 0.4 5.4e-64 216.2 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAN10461.1 - 8e-31 106.6 0.8 1.3e-30 105.8 0.4 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAN10461.1 - 3.6e-18 65.9 3.5 6.5e-16 58.7 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAN10461.1 - 9e-13 48.1 3.0 6e-12 45.4 3.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAN10461.1 - 5.1e-06 25.9 0.0 0.00014 21.1 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 GAN10461.1 - 6.1e-06 25.8 0.1 9.4e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAN10461.1 - 2.5e-05 23.7 0.5 0.061 12.6 0.0 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAN10461.1 - 3.8e-05 22.6 3.3 0.036 12.8 0.5 3.8 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_8 PF13450.6 GAN10461.1 - 0.00043 20.5 4.6 0.00043 20.5 4.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAN10461.1 - 0.0011 18.1 5.7 0.0054 15.9 3.4 2.7 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 GAN10461.1 - 0.0029 16.9 0.3 0.0091 15.3 0.3 1.8 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.19 GAN10461.1 - 0.003 16.9 0.0 0.003 16.9 0.0 2.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAN10461.1 - 0.0055 16.3 0.5 0.0086 15.7 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 GAN10461.1 - 0.011 14.9 6.3 0.46 9.5 4.6 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAN10461.1 - 0.011 15.6 1.5 0.013 15.4 0.0 1.9 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 GAN10461.1 - 0.013 15.1 13.2 0.034 13.7 3.7 3.3 3 1 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAN10461.1 - 0.11 13.0 0.9 3.1 8.3 0.0 2.8 3 1 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAN10461.1 - 0.12 11.4 0.1 0.9 8.5 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein MCRA PF06100.11 GAN10461.1 - 0.15 10.9 0.3 4.2 6.1 0.2 2.2 2 0 0 2 2 2 0 MCRA family Amino_oxidase PF01593.24 GAN10461.1 - 0.3 10.3 1.4 21 4.3 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF2433 PF10360.9 GAN10462.1 - 0.0074 16.4 0.1 0.0083 16.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) HD_4 PF13328.6 GAN10462.1 - 0.068 12.9 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 HD domain Inositol_P PF00459.25 GAN10464.1 - 1.8e-72 244.1 0.1 2.1e-72 243.9 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.32 GAN10466.1 - 2.7e-05 24.9 13.6 0.052 14.4 0.3 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat SRP54 PF00448.22 GAN10467.1 - 0.087 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain bZIP_2 PF07716.15 GAN10468.1 - 4.4e-10 39.5 12.8 4.4e-10 39.5 12.8 2.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN10468.1 - 6.1e-08 32.7 12.1 6.1e-08 32.7 12.1 1.8 1 1 1 2 2 2 1 bZIP transcription factor HAP1_N PF04849.13 GAN10468.1 - 0.0003 20.1 10.3 0.00044 19.6 10.3 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Pox_A_type_inc PF04508.12 GAN10468.1 - 0.0071 16.1 5.4 0.061 13.2 0.8 2.8 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat Shugoshin_N PF07558.11 GAN10468.1 - 0.28 11.1 3.8 0.17 11.8 1.2 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NAM-associated PF14303.6 GAN10468.1 - 0.31 11.7 10.6 0.45 11.2 10.6 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DPBB_1 PF03330.18 GAN10469.1 - 4.5e-14 52.5 0.2 1.6e-13 50.7 0.2 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN10469.1 - 0.00036 20.4 0.4 0.00036 20.4 0.4 2.1 2 0 0 2 2 2 1 Barwin family Pneumo_att_G PF05539.11 GAN10469.1 - 0.0041 16.8 19.8 0.077 12.6 14.6 2.1 2 0 0 2 2 2 2 Pneumovirinae attachment membrane glycoprotein G DUF5427 PF10310.9 GAN10469.1 - 0.16 10.9 12.0 0.22 10.4 12.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PilX_N PF14341.6 GAN10469.1 - 0.23 11.5 0.4 4.2 7.4 0.1 2.2 2 0 0 2 2 2 0 PilX N-terminal NPR3 PF03666.13 GAN10469.1 - 0.28 9.9 9.6 0.4 9.4 9.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GAN10469.1 - 0.3 9.8 6.1 0.34 9.6 6.1 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GAN10469.1 - 0.52 9.3 11.2 0.73 8.8 11.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MCM_bind PF09739.9 GAN10469.1 - 1.4 7.3 10.2 1.7 7.0 10.2 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Sec62 PF03839.16 GAN10469.1 - 2.2 7.7 9.3 3.6 7.1 9.3 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 PIN_4 PF13638.6 GAN10469.1 - 3.6 7.9 9.2 3.3 8.0 5.0 2.4 1 1 1 2 2 2 0 PIN domain DUF2981 PF11200.8 GAN10469.1 - 6 6.5 6.7 7.9 6.1 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) GREB1 PF15782.5 GAN10469.1 - 8.9 3.3 12.1 11 3.0 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mpp10 PF04006.12 GAN10469.1 - 9.9 4.5 20.3 14 4.0 20.3 1.1 1 0 0 1 1 1 0 Mpp10 protein DLH PF01738.18 GAN10470.1 - 7.3e-22 78.0 0.0 8.4e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAN10470.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAN10470.1 - 0.024 14.5 0.0 2.3 8.0 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold DAO PF01266.24 GAN10471.1 - 2.9e-38 132.4 0.0 3.5e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN10471.1 - 1.3e-06 28.5 0.0 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAN10471.1 - 5.1e-06 26.5 0.0 0.0034 17.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAN10471.1 - 1.2e-05 24.7 0.0 0.00068 19.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAN10471.1 - 0.00057 19.1 0.1 0.048 12.7 0.0 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 GAN10471.1 - 0.005 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GAN10471.1 - 0.018 13.8 0.1 0.89 8.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 GAN10471.1 - 0.07 13.1 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 GAN10471.1 - 0.096 11.5 0.1 0.23 10.3 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase HsbA PF12296.8 GAN10472.1 - 6.2e-13 49.2 1.9 6.2e-13 49.2 1.9 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A SesA PF17107.5 GAN10472.1 - 0.11 12.7 0.3 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 GAN10472.1 - 0.24 11.9 2.4 5.1 7.6 0.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COPI_assoc PF08507.10 GAN10473.1 - 7.3e-24 84.3 10.7 8.6e-24 84.1 10.7 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2583 PF10762.9 GAN10473.1 - 0.11 12.9 3.7 0.54 10.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) DUF2371 PF10177.9 GAN10473.1 - 0.15 12.3 3.8 0.29 11.3 0.2 2.2 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) MWFE PF15879.5 GAN10473.1 - 0.66 10.2 2.7 3.5 7.9 0.0 2.5 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Pam17 PF08566.10 GAN10474.1 - 1.6e-57 194.0 0.1 1.9e-57 193.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Romo1 PF10247.9 GAN10474.1 - 0.012 16.0 0.1 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 BsuBI_PstI_RE PF06616.11 GAN10475.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain SopA_C PF13979.6 GAN10476.1 - 0.048 13.4 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 SopA-like catalytic domain TPT PF03151.16 GAN10477.1 - 6.8e-30 104.4 22.1 8.3e-30 104.1 22.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAN10477.1 - 2.8e-11 43.7 30.4 5e-06 26.7 10.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAN10477.1 - 4.6e-07 29.3 21.0 4.9e-07 29.3 20.2 1.3 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 GAN10477.1 - 0.014 14.7 21.0 0.036 13.3 20.6 1.9 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Zip PF02535.22 GAN10479.1 - 2.2e-27 96.2 9.7 4.2e-27 95.3 9.7 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Lipase_3 PF01764.25 GAN10480.1 - 1.6e-13 50.8 0.0 3.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 GAN10480.1 - 2.6e-09 37.3 0.0 6.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Abhydrolase_1 PF00561.20 GAN10480.1 - 0.023 14.3 0.0 0.81 9.3 0.0 2.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAM60A PF15396.6 GAN10480.1 - 3.7 7.5 7.7 0.91 9.5 4.1 1.7 2 0 0 2 2 2 0 Protein Family FAM60A HlyIII PF03006.20 GAN10481.1 - 4.4e-24 85.5 9.0 5.8e-24 85.1 9.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related MHYT PF03707.16 GAN10483.1 - 2.4e-22 78.8 7.4 8.2e-10 38.7 0.8 3.5 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat DUF1344 PF07076.11 GAN10483.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) ABC2_membrane_5 PF13346.6 GAN10483.1 - 2 7.9 14.1 1.2 8.7 12.1 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein GST_N_3 PF13417.6 GAN10484.1 - 4.3e-13 49.5 0.0 9.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN10484.1 - 6.9e-05 23.1 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAN10484.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAN10484.1 - 0.024 15.0 0.0 0.082 13.3 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAN10485.1 - 1.4e-14 54.3 0.0 3.4e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN10485.1 - 1.1e-06 28.9 0.0 3.8e-06 27.1 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAN10485.1 - 0.00028 21.1 0.1 0.0047 17.2 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Flavin_Reduct PF01613.18 GAN10486.1 - 7.6e-40 136.5 0.1 1.2e-39 135.9 0.1 1.3 1 0 0 1 1 1 1 Flavin reductase like domain RVT_1 PF00078.27 GAN10487.1 - 9e-35 120.2 0.0 3.8e-34 118.1 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GAN10487.1 - 1.2e-07 31.5 0.4 2.5e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 GAN10487.1 - 0.0016 18.4 3.4 0.0016 18.4 3.4 3.3 3 0 0 3 3 3 2 Zinc knuckle Exo_endo_phos_2 PF14529.6 GAN10487.1 - 0.022 14.6 1.4 0.083 12.7 1.4 2.0 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase IstB_IS21_ATP PF08483.11 GAN10487.1 - 0.16 11.9 0.3 0.46 10.4 0.3 1.8 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal Ribosomal_L41 PF05162.13 GAN10487.1 - 0.28 11.3 6.3 0.74 9.9 6.3 1.7 1 0 0 1 1 1 0 Ribosomal protein L41 zf-CCHC_4 PF14392.6 GAN10487.1 - 0.85 9.4 6.2 6.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle Arrestin_N PF00339.29 GAN10488.1 - 0.00033 20.7 0.0 0.00033 20.7 0.0 2.6 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Cyclin PF08613.11 GAN10489.1 - 1.5e-09 38.4 1.1 1.5e-09 38.4 1.1 2.0 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAN10489.1 - 0.0043 16.8 4.8 0.023 14.4 4.8 2.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF3658 PF12395.8 GAN10489.1 - 0.015 15.2 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function PH PF00169.29 GAN10492.1 - 6.7e-20 71.6 1.8 1.7e-19 70.3 1.8 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 GAN10492.1 - 1.8e-17 63.2 1.3 2.6e-17 62.7 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN10492.1 - 1.2e-14 54.5 0.5 4.2e-14 52.7 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 GAN10492.1 - 2.9e-14 52.6 0.0 6.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN10492.1 - 2.6e-13 49.3 0.2 6.2e-13 48.1 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN10492.1 - 3.5e-09 36.2 0.0 7.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.31 GAN10492.1 - 5e-09 36.3 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_11 PF15413.6 GAN10492.1 - 2.3e-05 24.7 6.6 2.3e-05 24.7 6.6 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 GAN10492.1 - 0.00097 19.4 0.1 0.003 17.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_4 PF18017.1 GAN10492.1 - 0.0034 17.3 0.1 0.0083 16.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 GAN10492.1 - 0.084 13.1 0.3 3.9 7.8 0.2 2.5 2 0 0 2 2 2 0 Ste50p, sterile alpha motif PH_3 PF14593.6 GAN10492.1 - 0.29 11.2 2.5 0.28 11.3 0.8 1.8 2 0 0 2 2 1 0 PH domain ENTH PF01417.20 GAN10493.1 - 3.6e-46 156.3 0.8 7.9e-46 155.2 0.7 1.6 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 GAN10493.1 - 7.1e-06 25.2 0.4 1e-05 24.7 0.4 1.2 1 0 0 1 1 1 1 ANTH domain Biopterin_H PF00351.21 GAN10493.1 - 0.0051 15.9 0.5 0.0082 15.2 0.5 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase VHS PF00790.19 GAN10493.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 VHS domain peroxidase PF00141.23 GAN10494.1 - 1.9e-44 152.1 0.0 2.7e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase FYVE PF01363.21 GAN10495.1 - 3.4 7.9 6.2 2.3 8.4 1.8 2.4 1 1 1 2 2 2 0 FYVE zinc finger HNH_5 PF14279.6 GAN10496.1 - 0.0027 17.5 1.5 0.037 13.9 0.0 3.0 3 0 0 3 3 3 1 HNH endonuclease Stc1 PF12898.7 GAN10496.1 - 0.097 13.2 1.2 0.38 11.3 0.0 2.2 2 0 0 2 2 2 0 Stc1 domain HNH PF01844.23 GAN10497.1 - 8.8e-05 22.6 1.7 0.0011 19.1 0.0 3.2 3 1 0 3 3 3 1 HNH endonuclease HNH_5 PF14279.6 GAN10497.1 - 0.00027 20.7 0.0 0.00027 20.7 0.0 3.6 3 2 1 4 4 4 1 HNH endonuclease ASFV_p27 PF06556.11 GAN10497.1 - 0.057 13.5 1.5 1.2 9.3 0.2 2.6 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus zinc_ribbon_9 PF14369.6 GAN10497.1 - 0.1 12.8 7.7 4.4 7.7 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon DUF5623 PF18536.1 GAN10497.1 - 0.13 12.6 0.6 0.5 10.7 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) zf_C2HC_14 PF18574.1 GAN10497.1 - 3.1 7.7 7.3 2.8 7.8 0.2 3.2 3 0 0 3 3 3 0 C2HC Zing finger domain DZR PF12773.7 GAN10497.1 - 3.2 7.9 9.3 3.3 7.8 2.9 2.6 2 0 0 2 2 2 0 Double zinc ribbon IBR PF01485.21 GAN10497.1 - 6 7.2 11.4 1.5 9.1 2.4 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DUF485 PF04341.12 GAN10498.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 MgtE PF01769.16 GAN10498.1 - 0.89 9.9 7.4 2.9 8.3 3.6 2.3 2 0 0 2 2 2 0 Divalent cation transporter zf-RING_2 PF13639.6 GAN10499.1 - 2.7e-10 40.4 8.0 4.9e-10 39.6 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAN10499.1 - 9.4e-08 31.8 6.9 1.6e-07 31.0 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN10499.1 - 9.9e-08 31.7 8.2 1.7e-07 30.9 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN10499.1 - 6.6e-07 29.2 4.3 1.1e-06 28.5 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAN10499.1 - 2.7e-06 27.0 4.1 2.7e-06 27.0 4.1 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAN10499.1 - 4e-05 23.4 8.6 6.6e-05 22.7 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAN10499.1 - 0.00038 20.7 7.6 0.0014 18.9 7.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAN10499.1 - 0.00063 19.6 10.0 0.0012 18.7 10.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAN10499.1 - 0.0015 18.5 8.7 0.022 14.8 8.7 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAN10499.1 - 0.024 14.4 7.1 0.043 13.6 7.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF702 PF05142.12 GAN10499.1 - 0.1 13.0 2.1 0.22 12.0 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF1272 PF06906.11 GAN10499.1 - 0.12 12.5 5.2 0.27 11.3 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF2073 PF09846.9 GAN10499.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) ANAPC_CDC26 PF10471.9 GAN10499.1 - 0.48 11.3 13.1 0.089 13.6 8.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 zf-C3HC4_4 PF15227.6 GAN10499.1 - 0.57 10.4 7.4 1.5 9.1 7.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Spt20 PF12090.8 GAN10499.1 - 1.1 8.8 9.5 2.2 7.8 9.5 1.4 1 0 0 1 1 1 0 Spt20 family zf-RING_14 PF17978.1 GAN10501.1 - 4.8 7.7 9.0 10 6.6 1.1 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Cation_efflux PF01545.21 GAN10502.1 - 1.9e-49 168.1 11.3 2.5e-49 167.7 11.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 GAN10502.1 - 0.00048 20.0 0.3 0.0037 17.2 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF5134) TMEM141 PF15110.6 GAN10502.1 - 0.073 13.6 2.9 0.46 11.1 0.2 2.9 3 1 0 3 3 3 0 TMEM141 protein family DUF2162 PF09930.9 GAN10502.1 - 0.89 8.9 9.1 0.024 14.1 2.9 1.5 2 0 0 2 2 2 0 Predicted transporter (DUF2162) FGGY_C PF02782.16 GAN10503.1 - 1e-69 234.2 0.2 1.6e-69 233.6 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAN10503.1 - 4e-69 232.9 0.1 5.8e-69 232.4 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 GAN10503.1 - 0.02 14.4 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1295 PF06966.12 GAN10504.1 - 4.4e-41 140.9 4.8 6.2e-41 140.5 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Acyl_transf_2 PF02273.15 GAN10504.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase Ribosomal_L1 PF00687.21 GAN10505.1 - 5.6e-39 134.0 4.1 5.6e-39 134.0 4.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Alph_Pro_TM PF09608.10 GAN10505.1 - 0.033 14.0 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Phosphodiest PF01663.22 GAN10506.1 - 1.5e-06 28.1 1.8 0.00034 20.3 0.2 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4570 PF15134.6 GAN10506.1 - 0.046 13.8 1.5 0.094 12.7 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Orf78 PF06024.12 GAN10506.1 - 0.62 10.4 2.6 14 6.1 0.0 3.2 2 0 0 2 2 2 0 Orf78 (ac78) zf-C2H2_jaz PF12171.8 GAN10507.1 - 6.4e-06 26.3 4.0 0.032 14.5 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 GAN10507.1 - 1.6e-05 25.1 3.7 1.6e-05 25.1 3.7 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN10507.1 - 0.00081 20.0 12.6 0.077 13.9 1.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN10507.1 - 0.0016 18.8 10.6 0.059 13.8 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Mucin PF01456.17 GAN10507.1 - 0.031 14.3 22.4 0.083 12.9 22.4 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-met PF12874.7 GAN10507.1 - 0.036 14.4 4.3 0.75 10.3 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3439 PF11921.8 GAN10507.1 - 0.056 13.4 16.9 0.12 12.3 16.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 GAN10507.1 - 0.13 10.3 6.8 0.43 8.5 6.8 1.8 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein zinc_ribbon_9 PF14369.6 GAN10507.1 - 0.52 10.6 6.1 21 5.5 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon DUF5305 PF17231.2 GAN10507.1 - 0.69 9.3 3.9 1.3 8.4 3.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) zf-C2HC_2 PF13913.6 GAN10507.1 - 9.4 6.3 9.9 4.1 7.4 0.5 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type UNC-50 PF05216.13 GAN10508.1 - 7.6e-89 297.0 22.7 7.6e-89 297.0 22.7 1.7 1 1 1 2 2 2 1 UNC-50 family DUF1772 PF08592.11 GAN10508.1 - 0.19 12.0 7.8 1.5 9.1 1.8 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Homeodomain PF00046.29 GAN10509.1 - 1.6e-16 59.9 5.2 3e-16 59.0 5.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN10509.1 - 0.0058 16.5 0.6 0.013 15.4 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Hid1 PF12722.7 GAN10510.1 - 5.8e-224 745.8 6.0 6.7e-224 745.6 6.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAN10510.1 - 4.3e-114 382.2 2.3 5.7e-114 381.8 2.3 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein ANAPC2 PF08672.11 GAN10510.1 - 0.13 12.8 0.2 3.8 8.1 0.0 3.1 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 SRP-alpha_N PF04086.13 GAN10510.1 - 0.6 10.0 6.3 0.93 9.4 6.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4637 PF15470.6 GAN10510.1 - 2 8.1 6.5 0.14 11.9 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) zf-C2H2 PF00096.26 GAN10511.1 - 2.2e-11 43.5 7.0 8.6e-05 22.8 0.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN10511.1 - 4.3e-08 33.2 11.5 0.00069 19.9 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 GAN10511.1 - 2.1e-05 24.7 2.1 0.00026 21.3 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN10511.1 - 9.3e-05 22.6 4.4 0.0012 19.1 0.5 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAN10511.1 - 0.00036 21.1 6.6 0.0058 17.4 1.1 3.5 4 0 0 4 4 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 GAN10511.1 - 0.026 14.8 0.5 0.026 14.8 0.5 2.0 2 0 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 GAN10511.1 - 0.1 12.7 1.2 15 5.7 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 GAN10511.1 - 0.14 12.2 0.3 0.14 12.2 0.3 3.2 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAN10511.1 - 0.16 11.9 5.9 0.69 9.9 0.7 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 GAN10511.1 - 0.49 10.2 7.6 0.21 11.4 0.4 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 GAN10511.1 - 0.95 9.4 7.8 0.52 10.3 1.7 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain TFIIA PF03153.13 GAN10511.1 - 1.1 9.2 25.0 1.3 9.0 25.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 GAN10511.1 - 2.8 9.0 5.4 8.1 7.5 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PPV_E1_N PF00524.18 GAN10511.1 - 5.5 7.4 9.3 0.57 10.6 4.3 1.9 2 0 0 2 2 2 0 E1 Protein, N terminal domain PKI PF02827.16 GAN10511.1 - 8.8 6.6 7.6 7.3 6.9 0.1 2.5 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Tox-PLDMTX PF15645.6 GAN10512.1 - 0.022 15.1 0.3 0.028 14.7 0.3 1.2 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold DNA_topoisoIV PF00521.20 GAN10513.1 - 3.1e-113 378.9 0.1 5.7e-113 378.0 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAN10513.1 - 5.2e-45 152.9 0.9 5.2e-45 152.9 0.9 2.3 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAN10513.1 - 8.3e-26 90.5 0.3 2.5e-25 89.0 0.3 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAN10513.1 - 1.4e-12 48.1 0.0 3.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAN10513.1 - 2.8e-07 30.7 0.0 1.1e-06 28.8 0.0 2.1 1 0 0 1 1 1 1 Toprim domain DDE_Tnp_1_7 PF13843.6 GAN10514.1 - 1.1e-09 38.1 1.1 2.3e-07 30.4 0.5 2.2 1 1 1 2 2 2 2 Transposase IS4 DPBB_1 PF03330.18 GAN10515.1 - 2.6e-13 50.0 0.0 3.8e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAN10515.1 - 0.0037 17.1 0.4 0.0074 16.1 0.1 1.6 1 1 0 2 2 2 1 Barwin family Cyclin_N PF00134.23 GAN10516.1 - 8.5e-16 57.9 1.5 1.3e-15 57.2 1.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAN10516.1 - 0.00015 21.7 0.0 0.00047 20.1 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 GAN10516.1 - 0.00019 21.8 0.0 0.00076 19.8 0.0 2.1 1 1 0 1 1 1 1 Cyclin C-terminal domain RB_B PF01857.20 GAN10516.1 - 0.00073 19.6 2.3 0.62 10.1 0.0 2.3 2 0 0 2 2 2 2 Retinoblastoma-associated protein B domain VASt PF16016.5 GAN10517.1 - 2.5e-32 112.4 1.3 5.8e-32 111.2 1.3 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAN10517.1 - 8.4e-23 80.4 0.0 1.9e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Fib_alpha PF08702.10 GAN10517.1 - 0.22 11.7 7.4 1.9 8.6 0.5 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HU-CCDC81_bac_2 PF18175.1 GAN10520.1 - 0.078 12.9 0.1 0.8 9.6 0.0 2.0 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Sec3_C_2 PF15278.6 GAN10521.1 - 0.13 12.6 3.1 0.23 11.9 0.5 2.5 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Sds3 PF08598.11 GAN10522.1 - 6.9e-21 75.3 18.5 6.9e-21 75.3 18.5 1.6 2 0 0 2 2 2 1 Sds3-like HAD_2 PF13419.6 GAN10522.1 - 3e-16 60.0 1.5 2.1e-15 57.3 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN10522.1 - 1.1e-09 38.9 0.0 3.1e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN10522.1 - 0.00034 20.6 0.0 0.0008 19.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like ubiquitin PF00240.23 GAN10523.1 - 5.8e-94 307.9 11.8 5.8e-33 112.5 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 GAN10523.1 - 1.4e-40 136.9 10.7 2.6e-14 52.8 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAN10523.1 - 3.3e-17 62.7 6.2 0.00032 21.1 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 GAN10523.1 - 1.8e-13 50.2 0.2 0.00066 19.6 0.0 3.2 2 1 1 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAN10523.1 - 6.5e-11 42.5 2.9 0.028 14.8 0.1 3.1 2 1 1 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 GAN10523.1 - 4.8e-10 39.9 0.2 0.032 14.8 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAN10523.1 - 8.4e-09 35.5 0.5 0.35 11.0 0.0 3.9 2 2 1 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 GAN10523.1 - 3.5e-06 27.0 0.1 0.29 10.9 0.0 3.0 1 1 2 3 3 3 2 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 GAN10523.1 - 4.2e-05 23.5 13.1 16 5.6 0.2 5.8 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 GAN10523.1 - 8e-05 22.7 0.9 2.4 8.4 0.1 3.2 3 0 0 3 3 3 2 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 GAN10523.1 - 0.0011 19.3 0.0 29 5.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Raf1_HTH PF18579.1 GAN10523.1 - 0.0014 18.3 0.2 22 4.9 0.0 3.3 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_5 PF13710.6 GAN10523.1 - 0.0078 16.0 1.9 7.1 6.5 0.1 3.2 3 0 0 3 3 3 1 ACT domain UDP-g_GGTase PF06427.11 GAN10523.1 - 0.016 15.3 3.7 0.36 11.0 0.1 3.6 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_4 PF13291.6 GAN10523.1 - 0.044 14.4 0.4 43 4.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 GAN10523.1 - 0.046 14.3 0.0 54 4.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Big_3_3 PF13750.6 GAN10523.1 - 0.053 13.2 0.0 21 4.7 0.0 2.8 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) ProRS-C_2 PF09181.10 GAN10523.1 - 0.066 13.3 3.0 43 4.3 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal DUF969 PF06149.12 GAN10523.1 - 0.078 12.4 0.0 27 4.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF969) Plexin_cytopl PF08337.12 GAN10523.1 - 0.095 11.4 3.5 8 5.0 0.1 3.1 3 0 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Big_7 PF17957.1 GAN10523.1 - 0.11 13.2 0.0 33 5.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig domain Tash_PEST PF07708.11 GAN10523.1 - 0.3 11.3 9.6 4.2 7.7 1.5 2.6 2 0 0 2 2 2 0 Tash protein PEST motif DMA PF03474.14 GAN10523.1 - 0.36 10.5 1.7 1e+02 2.6 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Coagulin PF02035.15 GAN10523.1 - 0.42 10.5 0.8 56 3.6 0.0 2.8 3 0 0 3 3 3 0 Coagulin Acp26Ab PF05777.12 GAN10523.1 - 0.47 11.1 2.4 12 6.6 0.0 3.4 4 1 0 4 4 3 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) 3HCDH_N PF02737.18 GAN10524.1 - 1.2e-59 201.2 3.6 1.6e-59 200.8 3.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAN10524.1 - 1.6e-33 115.1 0.0 4.7e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAN10524.1 - 0.034 14.4 0.7 0.069 13.4 0.5 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 GAN10524.1 - 0.041 13.9 0.6 0.069 13.1 0.5 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RRM_1 PF00076.22 GAN10525.1 - 3.1e-20 71.8 0.0 1.2e-08 34.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 GAN10525.1 - 5.8e-17 60.4 1.1 2.8e-05 23.5 0.1 6.0 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DUF4523 PF15023.6 GAN10525.1 - 1.6e-05 24.8 0.0 0.098 12.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 GAN10525.1 - 0.00048 19.9 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GAN10525.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nab6_mRNP_bdg PF10567.9 GAN10525.1 - 0.096 12.1 0.1 0.096 12.1 0.1 2.3 4 0 0 4 4 4 0 RNA-recognition motif Pkinase PF00069.25 GAN10526.1 - 5.7e-64 216.0 0.0 1e-63 215.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10526.1 - 3.5e-43 147.7 0.3 1.5e-42 145.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN10526.1 - 5.4e-08 32.0 0.0 1.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAN10526.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN10526.1 - 0.0015 17.9 0.2 0.0033 16.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PBD PF00786.28 GAN10526.1 - 0.0068 16.7 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain APH PF01636.23 GAN10526.1 - 0.015 15.2 0.0 0.12 12.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAN10526.1 - 0.026 13.5 0.2 0.026 13.5 0.2 1.6 2 0 0 2 2 2 0 Haspin like kinase domain TRH PF05438.12 GAN10526.1 - 0.099 12.4 0.2 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Thyrotropin-releasing hormone (TRH) FTA2 PF13095.6 GAN10526.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.25 GAN10527.1 - 1.4e-15 57.3 0.0 5.9e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN10527.1 - 6.1e-07 29.2 0.0 0.0084 15.7 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN10527.1 - 4.3e-06 26.7 0.0 8.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN10527.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LEA_2 PF03168.13 GAN10528.1 - 0.096 13.2 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein UBD PF16455.5 GAN10530.1 - 2.7e-29 101.4 0.0 5.3e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-binding domain ACPS PF01648.20 GAN10530.1 - 1e-09 38.5 0.0 3e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF2407 PF10302.9 GAN10530.1 - 0.00025 21.5 1.2 0.00058 20.4 0.2 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAN10530.1 - 0.045 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin family SCAB-PH PF17684.1 GAN10530.1 - 0.081 13.2 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein DUF5310 PF17237.2 GAN10531.1 - 0.12 12.2 0.1 0.37 10.7 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Sel1 PF08238.12 GAN10533.1 - 1.1e-41 140.2 22.7 5.2e-09 36.5 0.1 7.3 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 GAN10533.1 - 0.36 11.6 0.3 0.36 11.6 0.3 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Nucleoporin_FG PF13634.6 GAN10533.1 - 0.36 11.7 8.8 0.93 10.4 8.8 1.7 1 0 0 1 1 1 0 Nucleoporin FG repeat region TMF_DNA_bd PF12329.8 GAN10533.1 - 1.1 9.4 3.6 2.4 8.2 3.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Ubiq-assoc PF09145.10 GAN10533.1 - 3.4 7.7 6.6 6.6 6.8 0.0 4.4 4 1 1 5 5 5 0 Ubiquitin-associated TPR_16 PF13432.6 GAN10533.1 - 4.6 8.0 15.0 13 6.5 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TIG PF01833.24 GAN10534.1 - 2.2e-10 40.5 1.8 5.3e-10 39.2 0.2 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 GAN10534.1 - 5.9e-05 23.6 0.4 0.00012 22.6 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN10534.1 - 7e-05 23.0 0.2 0.043 14.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN10534.1 - 0.0032 17.8 0.6 4.1 8.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAN10534.1 - 0.0048 17.3 1.5 0.39 11.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAN10534.1 - 0.016 15.8 0.2 0.075 13.6 0.2 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.21 GAN10535.1 - 9e-86 288.3 0.0 1e-85 288.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Vitellogenin_N PF01347.22 GAN10535.1 - 0.031 12.7 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region hnRNP_Q_AcD PF18360.1 GAN10535.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Dak1 PF02733.17 GAN10536.1 - 4.2e-109 364.2 3.9 5.2e-109 363.9 3.9 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GAN10536.1 - 6.1e-42 143.5 0.1 1.3e-41 142.4 0.1 1.6 1 0 0 1 1 1 1 DAK2 domain eIF3_subunit PF08597.10 GAN10538.1 - 3.1e-52 177.9 31.2 3.1e-52 177.9 31.2 2.3 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit DUF1664 PF07889.12 GAN10538.1 - 0.56 10.2 7.2 1.8 8.6 7.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 GAN10538.1 - 0.82 10.0 3.4 3.1 8.1 3.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) VTC PF09359.10 GAN10539.1 - 7e-50 169.9 0.6 7e-50 169.9 0.6 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 GAN10539.1 - 1.6e-15 57.9 8.4 3.5e-08 33.8 0.7 2.6 1 1 0 2 2 2 2 SPX domain DUF202 PF02656.15 GAN10539.1 - 3e-13 50.0 1.9 6.1e-13 49.0 1.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) CTNNBL PF08216.11 GAN10539.1 - 0.089 13.0 0.5 0.22 11.7 0.5 1.7 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear DUF4387 PF14330.6 GAN10539.1 - 0.13 13.0 0.0 0.77 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4387) VTC PF09359.10 GAN10540.1 - 9.2e-82 274.5 0.1 3.2e-81 272.7 0.0 1.9 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAN10540.1 - 4.1e-13 49.6 3.0 4.1e-13 49.6 3.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAN10540.1 - 7.9e-10 39.2 12.9 0.00019 21.5 0.2 4.2 2 1 2 4 4 4 3 SPX domain HD_3 PF13023.6 GAN10540.1 - 0.0097 15.8 0.4 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 HD domain DUF4482 PF14818.6 GAN10540.1 - 0.23 12.4 1.5 0.35 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) DUF2157 PF09925.9 GAN10540.1 - 0.5 10.1 3.1 0.82 9.4 0.4 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 GAN10540.1 - 9.1 4.9 7.0 7.1 5.3 0.2 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) CAP_C PF08603.11 GAN10541.1 - 0.011 15.3 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Hydrolase_6 PF13344.6 GAN10544.1 - 4e-26 91.1 0.0 6.6e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN10544.1 - 4.2e-16 58.8 0.0 1.1e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAN10544.1 - 4.5e-05 23.8 0.1 0.0016 18.8 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN10544.1 - 0.00017 21.8 0.0 0.052 13.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 GAN10544.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF1358 PF07096.11 GAN10545.1 - 6.5e-08 32.6 0.1 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1358) LapA_dom PF06305.11 GAN10545.1 - 0.084 12.7 2.3 0.23 11.3 0.3 2.3 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-C2H2 PF00096.26 GAN10546.1 - 8.8e-07 29.1 1.4 8.8e-07 29.1 1.4 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN10546.1 - 0.00094 19.8 1.6 0.0026 18.5 1.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger FOXP-CC PF16159.5 GAN10546.1 - 0.0079 16.8 0.1 0.021 15.5 0.1 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 GAN10546.1 - 0.12 12.9 8.9 0.59 10.7 1.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain DUF908 PF06012.12 GAN10546.1 - 1.4 8.2 4.4 1.5 8.2 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HMG_box PF00505.19 GAN10547.1 - 1.6e-14 54.1 0.3 1.6e-14 54.1 0.3 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN10547.1 - 8e-10 39.2 0.1 8e-10 39.2 0.1 3.0 2 1 1 3 3 3 1 HMG-box domain SAM_1 PF00536.30 GAN10547.1 - 9.5e-10 38.8 0.1 1e-08 35.5 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAN10547.1 - 5.9e-06 26.3 0.4 1.5e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 GAN10547.1 - 0.0014 18.6 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Rpr2 PF04032.16 GAN10548.1 - 2.9e-17 62.7 2.3 2.9e-17 62.7 2.3 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ADD_DNMT3 PF17980.1 GAN10548.1 - 0.03 14.3 0.3 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Paired_CXXCH_1 PF09699.10 GAN10548.1 - 0.36 10.6 3.6 2.5 7.9 1.4 3.0 1 1 1 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Mito_carr PF00153.27 GAN10549.1 - 1.2e-19 70.0 5.7 6.9e-15 54.7 0.2 3.1 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF1992 PF09350.10 GAN10550.1 - 6.4e-23 80.7 0.6 1.5e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) DUF4140 PF13600.6 GAN10550.1 - 0.032 14.7 0.6 0.27 11.7 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) VIR_N PF15912.5 GAN10550.1 - 0.59 9.7 5.9 0.29 10.7 3.6 1.6 1 1 0 1 1 1 0 Virilizer, N-terminal Vma12 PF11712.8 GAN10550.1 - 2.4 8.2 6.5 5.2 7.1 6.2 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Dickkopf_N PF04706.12 GAN10551.1 - 0.039 14.4 9.7 0.084 13.4 9.7 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Pox_A14 PF05767.12 GAN10551.1 - 0.053 13.7 0.3 4.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 EB PF01683.18 GAN10551.1 - 8.6 6.7 16.5 0.15 12.4 8.8 2.0 2 0 0 2 2 2 0 EB module EB PF01683.18 GAN10552.1 - 1.4 9.3 18.9 0.071 13.4 9.3 2.8 2 1 1 3 3 3 0 EB module UPF0506 PF11703.8 GAN10552.1 - 8.8 6.8 14.2 0.16 12.3 5.8 2.1 2 0 0 2 2 2 0 UPF0506 adh_short_C2 PF13561.6 GAN10553.1 - 2.6e-57 194.1 6.1 3e-57 193.9 6.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN10553.1 - 4.2e-42 143.8 2.2 5.1e-42 143.5 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN10553.1 - 5.2e-06 26.5 1.5 1.1e-05 25.5 0.8 1.8 2 1 0 2 2 2 1 KR domain Acetyltransf_4 PF13420.7 GAN10554.1 - 7e-21 75.0 0.1 8.1e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAN10554.1 - 4.1e-10 40.5 0.0 5.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN10554.1 - 2e-08 34.5 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAN10554.1 - 1.3e-05 25.1 0.1 2.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GAN10554.1 - 2.4e-05 24.7 0.0 3.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN10554.1 - 0.00059 19.8 0.0 0.00079 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 GAN10554.1 - 0.057 13.2 0.1 0.085 12.6 0.1 1.5 1 1 0 1 1 1 0 GNAT acetyltransferase, Mec-17 CRCB PF02537.15 GAN10555.1 - 3.3e-34 117.1 13.2 2.2e-20 72.7 6.0 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF3481 PF11980.8 GAN10555.1 - 0.028 14.1 1.6 4.2 7.1 0.0 3.7 4 0 0 4 4 4 0 C-terminal domain of neuropilin glycoprotein Methyltransf_16 PF10294.9 GAN10556.1 - 1.7e-11 44.2 0.0 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 GAN10556.1 - 5.4e-07 29.6 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN10556.1 - 5.4e-05 23.0 0.0 0.0059 16.4 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN10556.1 - 0.0018 19.0 0.0 2.6 8.8 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAN10556.1 - 0.0078 16.9 1.7 0.72 10.6 0.1 3.4 2 2 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 GAN10556.1 - 0.01 15.2 0.3 0.16 11.3 0.0 2.7 3 0 0 3 3 3 0 Tellurite resistance protein TehB MTS PF05175.14 GAN10556.1 - 0.057 13.0 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain RNase_H2_suC PF08615.11 GAN10556.1 - 3.2 7.9 4.8 14 5.8 5.0 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Astro_capsid_p PF12226.8 GAN10556.1 - 4 6.5 8.0 7 5.7 8.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Defensin_like PF10868.8 GAN10557.1 - 0.003 18.3 19.7 0.14 12.9 10.8 2.2 1 1 1 2 2 2 2 Cysteine-rich antifungal protein 2, defensin-like SLR1-BP PF07333.12 GAN10557.1 - 0.013 15.9 19.9 0.33 11.4 5.6 2.3 1 1 1 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Toxin_2 PF00451.19 GAN10557.1 - 0.04 14.2 19.7 0.064 13.6 7.5 2.8 2 1 0 2 2 2 0 Scorpion short toxin, BmKK2 Gamma-thionin PF00304.20 GAN10557.1 - 0.38 11.1 18.4 0.15 12.3 6.4 2.3 2 0 0 2 2 2 0 Gamma-thionin family Defensin_beta PF00711.19 GAN10557.1 - 3.7 7.6 12.8 0.088 12.9 2.8 2.6 3 0 0 3 3 3 0 Beta defensin XPA_C PF05181.12 GAN10559.1 - 1.5e-25 88.9 1.7 5.5e-25 87.1 1.6 2.0 2 0 0 2 2 2 1 XPA protein C-terminus TF_Zn_Ribbon PF08271.12 GAN10559.1 - 0.012 15.1 0.6 0.012 15.1 0.6 3.1 2 1 1 3 3 3 0 TFIIB zinc-binding zf-C3HC4_3 PF13920.6 GAN10559.1 - 0.048 13.5 2.2 0.053 13.4 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) W2 PF02020.18 GAN10559.1 - 0.084 13.0 1.3 1 9.5 0.7 2.4 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon CpXC PF14353.6 GAN10559.1 - 0.13 12.3 3.9 0.12 12.4 1.1 2.5 2 1 0 2 2 2 0 CpXC protein zf-CpG_bind_C PF12269.8 GAN10559.1 - 0.4 10.4 7.7 0.05 13.4 0.9 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain zf_UBZ PF18439.1 GAN10559.1 - 0.58 9.8 8.4 1.9 8.2 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 GAN10559.1 - 0.84 9.7 9.7 0.055 13.5 4.0 2.0 2 0 0 2 2 2 0 XPA protein N-terminal S10_plectin PF03501.15 GAN10560.1 - 1.5e-43 146.8 0.1 1.7e-43 146.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Kinase-like PF14531.6 GAN10560.1 - 0.058 12.7 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like TrmB PF01978.19 GAN10560.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF1495 PF07381.11 GAN10560.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF2250 PF10007.9 GAN10560.1 - 0.39 10.9 1.0 20 5.4 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) WD40 PF00400.32 GAN10561.1 - 1.2e-14 54.5 2.3 7.1e-05 23.5 0.4 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10561.1 - 8.1e-08 32.5 0.1 3.8 7.9 0.0 5.0 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PTP2 PF17022.5 GAN10561.1 - 0.045 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia Mg_trans_NIPA PF05653.14 GAN10562.1 - 9.7e-62 208.7 16.0 9.1e-59 199.0 16.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAN10562.1 - 1.2e-05 25.5 2.0 1.2e-05 25.5 2.0 3.8 3 1 0 3 3 3 1 EamA-like transporter family GPR_Gpa2_C PF11970.8 GAN10562.1 - 0.058 13.5 1.4 0.16 12.1 1.4 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3453 PF11935.8 GAN10564.1 - 2e-30 106.2 8.3 2.4e-28 99.3 5.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3453) PEHE PF15275.6 GAN10564.1 - 0.034 14.8 0.2 0.034 14.8 0.2 2.8 2 1 0 2 2 2 0 PEHE domain YceD PF02620.17 GAN10564.1 - 0.5 10.5 5.5 0.21 11.7 0.5 2.6 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD Ras PF00071.22 GAN10565.1 - 5.5e-53 178.9 0.0 6.3e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN10565.1 - 8.7e-22 77.6 0.0 2e-21 76.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN10565.1 - 8.1e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAN10565.1 - 0.00046 20.1 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 GAN10565.1 - 0.0077 16.0 0.3 0.23 11.2 0.3 2.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GAN10565.1 - 0.028 14.8 0.0 0.066 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 GAN10565.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 GAN10565.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Arginase PF00491.21 GAN10565.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Arginase family RNase_P_pop3 PF08228.11 GAN10566.1 - 5.3e-12 46.1 1.2 8.1e-10 39.0 1.2 2.3 1 1 0 1 1 1 1 RNase P subunit Pop3 Abhydrolase_3 PF07859.13 GAN10567.1 - 5.8e-15 55.7 0.0 3.9e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAN10567.1 - 4.3e-08 32.5 0.0 0.0017 17.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 GAN10567.1 - 1.5e-07 31.0 0.1 7.6e-07 28.6 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAN10567.1 - 1.8e-06 27.6 0.0 3.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAN10567.1 - 6.6e-06 26.9 0.0 7.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAN10567.1 - 0.00034 20.3 3.9 0.00072 19.3 1.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAN10567.1 - 0.0007 19.5 0.2 0.0047 16.7 0.1 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 GAN10567.1 - 0.00094 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 GAN10567.1 - 0.00097 18.1 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF1749 PF08538.10 GAN10567.1 - 0.0046 16.1 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DLH PF01738.18 GAN10567.1 - 0.0062 16.1 0.0 0.14 11.7 0.1 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2974 PF11187.8 GAN10567.1 - 0.0078 15.8 0.1 0.011 15.3 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 GAN10567.1 - 0.009 15.7 0.3 0.012 15.3 0.3 1.4 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 GAN10567.1 - 0.011 15.9 0.0 0.96 9.5 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Esterase_phd PF10503.9 GAN10567.1 - 0.019 14.5 0.0 0.19 11.2 0.0 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.25 GAN10567.1 - 0.031 14.2 0.0 0.2 11.5 0.0 2.1 1 1 1 2 2 2 0 Lipase (class 3) Lipase PF00151.19 GAN10567.1 - 0.031 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipase Esterase PF00756.20 GAN10567.1 - 0.034 13.8 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative esterase Lipase_2 PF01674.18 GAN10567.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Ribosomal_L37 PF08561.10 GAN10568.1 - 5.7e-22 78.5 7.3 3.4e-20 72.7 4.2 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 SH3_1 PF00018.28 GAN10569.1 - 3.1e-40 135.5 8.3 9.1e-15 54.0 0.5 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 GAN10569.1 - 3.1e-38 129.4 9.0 1.2e-12 47.5 0.4 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 GAN10569.1 - 1.5e-32 111.2 0.1 3.2e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 GAN10569.1 - 8.7e-30 102.2 0.2 4.2e-09 36.0 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 GAN10569.1 - 1.3e-05 25.4 3.3 0.26 11.6 1.1 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_10 PF17902.1 GAN10569.1 - 0.00016 21.7 0.5 1.6 8.8 0.1 3.7 3 0 0 3 3 3 2 SH3 domain hSH3 PF14603.6 GAN10569.1 - 0.027 14.9 0.5 5.1 7.6 0.0 4.0 4 0 0 4 4 4 0 Helically-extended SH3 domain Caldesmon PF02029.15 GAN10569.1 - 0.031 13.1 67.3 0.0041 15.9 41.0 2.5 2 0 0 2 2 2 0 Caldesmon Nkap_C PF06047.11 GAN10570.1 - 5.8e-46 154.8 3.3 1.7e-45 153.3 3.3 1.8 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Peptidase_S64 PF08192.11 GAN10570.1 - 1.2 7.5 18.1 1.8 6.9 18.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 PIP5K PF01504.18 GAN10571.1 - 1.3e-96 323.0 0.5 2.4e-96 322.2 0.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FucT_N PF18025.1 GAN10571.1 - 0.073 13.5 0.1 0.31 11.5 0.1 2.0 1 0 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain Yae1_N PF09811.9 GAN10572.1 - 4.2e-12 45.6 2.9 6e-12 45.1 2.9 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal LRR_8 PF13855.6 GAN10573.1 - 6.4e-26 89.9 32.0 1.5e-10 40.6 2.3 5.5 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAN10573.1 - 5.6e-21 74.3 19.9 1.3e-05 25.4 1.0 6.5 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAN10573.1 - 5.8e-07 29.1 22.5 1 9.6 1.4 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_9 PF14580.6 GAN10573.1 - 6.4e-07 29.0 4.4 0.0032 17.0 0.8 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 GAN10573.1 - 4.1e-06 26.6 18.5 2.7 8.9 0.1 8.5 8 1 0 8 8 8 2 Leucine Rich Repeat zinc_ribbon_9 PF14369.6 GAN10573.1 - 0.023 15.0 0.1 0.055 13.7 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon HTH_Tnp_Tc3_2 PF01498.18 GAN10574.1 - 3e-14 53.0 1.8 3.4e-14 52.8 0.8 1.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 GAN10574.1 - 3.7e-07 30.0 0.5 4.7e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_21 PF13276.6 GAN10574.1 - 0.0023 18.0 0.8 0.011 15.8 0.1 2.5 2 1 0 2 2 2 1 HTH-like domain HTH_32 PF13565.6 GAN10574.1 - 0.018 15.7 0.0 0.37 11.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain RVT_1 PF00078.27 GAN10575.1 - 0.031 13.8 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) BTB_2 PF02214.22 GAN10576.1 - 4.2e-15 55.9 0.6 6.9e-15 55.2 0.6 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAN10576.1 - 0.00096 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MutS_V PF00488.21 GAN10577.1 - 4.8e-46 157.2 0.2 1.8e-45 155.3 0.0 2.0 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 GAN10577.1 - 2.3e-10 41.0 0.8 2.3e-10 41.0 0.8 2.0 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 GAN10577.1 - 0.022 15.1 0.7 0.25 11.7 0.1 3.1 2 1 0 2 2 2 0 MutS family domain IV BING4CT PF08149.11 GAN10577.1 - 0.11 12.3 0.5 0.29 11.0 0.5 1.7 1 0 0 1 1 1 0 BING4CT (NUC141) domain AAA PF00004.29 GAN10578.1 - 1.5e-55 187.2 0.1 6.2e-39 133.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN10578.1 - 1.8e-11 43.6 0.1 4.2e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAN10578.1 - 2.3e-09 37.6 5.1 1.6e-06 28.4 0.1 3.6 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAN10578.1 - 5e-09 36.6 0.2 0.0005 20.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAN10578.1 - 7.3e-09 36.2 0.2 0.01 16.2 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 GAN10578.1 - 1.3e-08 34.8 0.1 0.0032 17.2 0.1 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAN10578.1 - 3.8e-08 32.9 0.4 0.0099 15.1 0.1 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 GAN10578.1 - 1.7e-07 31.3 0.2 0.0011 19.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 GAN10578.1 - 4.8e-07 29.8 1.4 0.012 15.5 0.0 3.7 3 1 0 3 3 3 2 NACHT domain AAA_18 PF13238.6 GAN10578.1 - 4.9e-07 30.4 0.0 0.016 15.8 0.0 3.5 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 GAN10578.1 - 1.5e-06 27.8 0.2 0.0047 16.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 GAN10578.1 - 4.4e-06 26.7 0.0 0.048 13.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAN10578.1 - 5.7e-06 26.7 0.0 0.028 14.8 0.0 3.2 3 0 0 3 3 2 2 RNA helicase CDC48_2 PF02933.17 GAN10578.1 - 7.2e-06 25.7 0.6 0.00011 21.9 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_24 PF13479.6 GAN10578.1 - 7.4e-06 25.8 0.3 0.021 14.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAN10578.1 - 7.8e-06 26.1 0.0 0.19 11.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain CDC48_N PF02359.18 GAN10578.1 - 1.2e-05 25.3 0.0 5.3e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.17 GAN10578.1 - 1.5e-05 24.8 0.1 0.075 12.8 0.0 3.1 4 0 0 4 4 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 GAN10578.1 - 1.6e-05 24.5 0.8 0.023 14.2 0.1 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAN10578.1 - 1.8e-05 24.5 0.1 0.22 11.2 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 GAN10578.1 - 4e-05 23.7 0.0 0.39 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 GAN10578.1 - 5e-05 22.8 0.0 0.1 12.0 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 GAN10578.1 - 9.1e-05 23.0 0.2 0.18 12.3 0.0 3.1 2 2 0 2 2 2 1 ABC transporter ATPase PF06745.13 GAN10578.1 - 0.00012 21.5 0.5 0.015 14.7 0.0 2.8 2 1 0 2 2 2 1 KaiC AAA_30 PF13604.6 GAN10578.1 - 0.00021 21.1 0.7 0.28 10.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 GAN10578.1 - 0.00023 21.1 0.4 8.4 6.2 0.0 4.0 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GAN10578.1 - 0.00052 19.3 0.2 0.9 8.7 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain AAA_3 PF07726.11 GAN10578.1 - 0.0011 18.8 0.0 0.1 12.5 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 GAN10578.1 - 0.0027 16.8 0.0 0.76 8.8 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 GAN10578.1 - 0.0058 16.9 0.0 0.89 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 GAN10578.1 - 0.0061 16.4 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 GAN10578.1 - 0.0061 15.7 0.0 2.2 7.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Cytidylate_kin PF02224.18 GAN10578.1 - 0.0081 15.9 0.1 1.2 8.8 0.0 2.9 2 0 0 2 2 2 1 Cytidylate kinase ResIII PF04851.15 GAN10578.1 - 0.0088 16.1 0.0 5 7.1 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 GAN10578.1 - 0.011 15.6 0.0 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAN10578.1 - 0.012 15.9 2.9 0.99 9.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 GAN10578.1 - 0.013 15.1 6.8 1.8 8.1 0.0 4.4 5 1 0 6 6 5 0 AAA domain DUF2075 PF09848.9 GAN10578.1 - 0.019 14.2 0.2 5.1 6.2 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.10 GAN10578.1 - 0.027 14.5 0.1 0.15 12.1 0.0 2.3 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 GAN10578.1 - 0.029 14.8 0.0 12 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 GAN10578.1 - 0.043 13.6 0.3 36 4.1 0.0 3.4 2 2 1 3 3 3 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 GAN10578.1 - 0.051 13.3 0.1 5.9 6.7 0.0 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 GAN10578.1 - 0.054 13.6 0.0 25 5.0 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAN10578.1 - 0.081 12.2 0.2 2.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 GAN10578.1 - 0.27 10.8 1.6 10 5.7 0.1 3.1 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Hydrolase_4 PF12146.8 GAN10579.1 - 1.3e-55 188.2 0.0 1.6e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAN10579.1 - 2.1e-11 44.0 0.2 1.8e-10 40.9 0.2 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN10579.1 - 1.4e-09 38.9 0.0 1.5e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAN10579.1 - 0.0054 16.2 0.4 0.013 15.0 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAN10579.1 - 0.0063 16.3 0.2 0.13 12.1 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF1749 PF08538.10 GAN10579.1 - 0.014 14.5 0.1 0.033 13.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) DLH PF01738.18 GAN10579.1 - 0.02 14.5 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.15 GAN10579.1 - 0.025 13.7 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HMMR_C PF15908.5 GAN10579.1 - 0.035 14.4 0.1 0.066 13.5 0.1 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Thioesterase PF00975.20 GAN10579.1 - 0.054 13.6 0.3 1.2 9.1 0.1 2.4 2 1 0 2 2 2 0 Thioesterase domain DUF3089 PF11288.8 GAN10579.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) UQ_con PF00179.26 GAN10580.1 - 4.6e-22 78.2 0.1 8.3e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RE_ScaI PF09569.10 GAN10580.1 - 0.017 14.9 0.5 0.024 14.3 0.5 1.2 1 0 0 1 1 1 0 ScaI restriction endonuclease Orf78 PF06024.12 GAN10580.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) zf-H2C2_2 PF13465.6 GAN10581.1 - 1.8e-22 78.7 22.0 4.1e-08 33.3 0.2 5.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 GAN10581.1 - 3.2e-15 55.6 32.4 0.00084 19.7 1.8 7.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAN10581.1 - 1.1e-10 42.0 22.5 0.011 16.3 0.6 5.9 2 1 4 6 6 6 4 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAN10581.1 - 2.8e-06 27.7 49.7 0.0079 17.0 1.1 8.0 8 0 0 8 8 8 5 C2H2-type zinc finger zf_UBZ PF18439.1 GAN10581.1 - 0.0017 17.9 5.1 0.81 9.3 0.1 3.7 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 GAN10581.1 - 0.025 14.8 3.5 0.025 14.8 3.5 3.7 2 1 2 4 4 4 0 TFIIH C1-like domain zf-C2H2_11 PF16622.5 GAN10581.1 - 0.027 14.2 7.6 0.49 10.2 0.3 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 GAN10581.1 - 0.13 12.6 0.2 0.13 12.6 0.2 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding GCR1_C PF12550.8 GAN10581.1 - 0.15 12.4 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes FGGY_N PF00370.21 GAN10582.1 - 6.9e-77 258.3 0.0 1.2e-76 257.5 0.0 1.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAN10582.1 - 5.7e-66 222.0 1.3 7.4e-65 218.4 0.8 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain LCM PF04072.14 GAN10583.1 - 1.1e-24 87.5 0.0 4.1e-24 85.6 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1421 PF07223.11 GAN10583.1 - 0.02 14.7 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain (DUF1421) MFS_1 PF07690.16 GAN10584.1 - 1.5e-35 122.8 29.8 1.5e-35 122.8 29.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Thiolase_N PF00108.23 GAN10585.1 - 1.6e-80 270.2 2.8 2.7e-80 269.5 2.8 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN10585.1 - 2.7e-47 159.4 0.2 6.3e-47 158.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 GAN10585.1 - 0.0048 17.1 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal GATA PF00320.27 GAN10586.1 - 1.3e-27 95.1 18.8 1.8e-14 53.0 4.6 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAN10586.1 - 0.015 14.8 5.2 1.5 8.4 0.8 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding TDP43_N PF18694.1 GAN10586.1 - 0.045 13.6 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain eIF-5_eIF-2B PF01873.17 GAN10586.1 - 0.21 11.4 5.0 5.7 6.8 0.6 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 LIM PF00412.22 GAN10586.1 - 0.42 10.9 5.2 5 7.4 0.3 2.6 2 0 0 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.10 GAN10586.1 - 0.53 10.5 6.4 2.6 8.2 0.3 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 GAN10586.1 - 1.2 9.4 6.8 2.5 8.3 0.7 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RETICULATA-like PF11891.8 GAN10588.1 - 0.47 10.3 1.4 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein RETICULATA-related Ribonuclease_3 PF00636.26 GAN10589.1 - 1.8e-44 150.7 0.0 2.4e-21 76.3 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAN10589.1 - 1.2e-29 103.1 0.0 5.8e-17 62.1 0.0 3.2 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 GAN10589.1 - 2.7e-21 75.5 0.8 3.6e-19 68.7 0.0 3.7 4 0 0 4 4 4 1 Dicer dimerisation domain Helicase_C PF00271.31 GAN10589.1 - 1.7e-20 73.4 0.3 5.5e-20 71.8 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN10589.1 - 5.1e-14 52.6 0.2 1.6e-13 51.0 0.2 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAN10589.1 - 2.4e-12 46.9 0.0 4.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PAZ PF02170.22 GAN10589.1 - 9.3e-11 41.7 0.5 2.3e-10 40.4 0.5 1.7 1 0 0 1 1 1 1 PAZ domain SWI2_SNF2 PF18766.1 GAN10589.1 - 8.3e-06 25.6 0.2 3.5e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase APOBEC4_like PF18774.1 GAN10589.1 - 0.043 13.7 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase dsrm PF00035.26 GAN10589.1 - 0.1 13.4 0.2 0.3 11.8 0.2 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribosomal_S6 PF01250.17 GAN10590.1 - 2.6e-24 85.3 0.0 3e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 RabGAP-TBC PF00566.18 GAN10592.1 - 4.7e-30 104.9 2.4 3.2e-25 89.1 0.1 2.9 2 1 0 2 2 2 2 Rab-GTPase-TBC domain DUF2141 PF09912.9 GAN10593.1 - 0.0028 17.6 0.4 0.0047 16.8 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) TPR_2 PF07719.17 GAN10594.1 - 2.9e-10 39.5 0.1 0.00048 20.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAN10594.1 - 1.9e-09 36.9 0.0 0.0005 19.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10594.1 - 1.9e-08 34.7 0.2 4.6e-08 33.5 0.2 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAN10594.1 - 1.8e-07 30.7 0.0 0.00024 20.7 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 GAN10594.1 - 1.7e-06 28.3 0.6 0.01 16.5 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10594.1 - 0.00011 22.8 0.0 0.0003 21.4 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10594.1 - 0.00016 21.6 0.0 0.011 15.9 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAN10594.1 - 0.00054 20.1 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAN10594.1 - 0.014 15.7 0.4 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAN10594.1 - 0.04 13.9 0.0 5 7.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10594.1 - 0.13 12.7 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN10594.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BRCA-2_OB1 PF09103.10 GAN10595.1 - 1.2e-20 73.7 0.6 7.9e-19 67.8 0.2 3.0 2 1 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 GAN10595.1 - 1.6e-13 50.7 0.8 1.2e-11 44.7 0.9 2.7 2 1 1 3 3 3 1 BRCA2, helical BRCA-2_OB3 PF09104.10 GAN10595.1 - 0.00025 20.7 0.3 0.00089 18.9 0.1 1.9 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 PF00634.18 GAN10595.1 - 0.00073 19.2 6.6 1.6 8.5 0.0 4.0 4 0 0 4 4 4 3 BRCA2 repeat FMN_red PF03358.15 GAN10596.1 - 1.2e-14 54.3 0.1 1.8e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAN10596.1 - 1.5e-08 34.6 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 GAN10596.1 - 0.0045 17.2 0.1 0.15 12.3 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 GAN10597.1 - 1.1e-12 47.9 0.0 1.1e-12 47.9 0.0 2.4 3 0 0 3 3 3 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAN10597.1 - 3.7e-05 23.5 0.0 6.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold PIP5K PF01504.18 GAN10598.1 - 7.9e-99 330.3 0.5 1.4e-98 329.5 0.5 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Kinesin PF00225.23 GAN10599.1 - 8.9e-106 353.6 6.1 1.8e-62 211.2 0.4 4.6 5 1 1 6 6 6 2 Kinesin motor domain Microtub_bd PF16796.5 GAN10599.1 - 5.9e-21 75.0 1.1 1.4e-19 70.5 0.4 6.3 7 1 1 8 8 8 2 Microtubule binding Tub PF01167.18 GAN10601.1 - 4.3e-78 262.4 0.0 6e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Tub family TBCC PF07986.12 GAN10602.1 - 1.2e-26 92.8 2.0 2.2e-26 92.0 2.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 GAN10602.1 - 6.4e-17 62.1 6.6 6.4e-17 62.1 6.6 1.9 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain DUF3080 PF11279.8 GAN10602.1 - 0.011 15.0 2.6 0.011 15.0 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) NumbF PF06311.12 GAN10602.1 - 0.041 14.4 0.2 0.19 12.3 0.2 2.1 2 0 0 2 2 2 0 NUMB domain Allexi_40kDa PF05549.11 GAN10602.1 - 5.2 6.5 7.5 0.24 10.9 1.7 1.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein Med4 PF10018.9 GAN10603.1 - 8.2e-24 84.4 3.8 1.4e-23 83.6 3.8 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF2999 PF11212.8 GAN10603.1 - 0.1 12.9 1.9 0.4 11.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2999) DUF1640 PF07798.11 GAN10604.1 - 2.9e-51 174.0 10.2 3.3e-51 173.8 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.12 GAN10604.1 - 0.00017 21.6 9.6 0.00017 21.6 9.6 2.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 GAN10604.1 - 0.016 14.7 13.7 0.021 14.3 13.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 GAN10604.1 - 0.029 14.0 3.2 0.036 13.7 3.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit KASH_CCD PF14662.6 GAN10604.1 - 0.037 13.8 17.2 0.08 12.8 17.0 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Mitofilin PF09731.9 GAN10604.1 - 0.038 12.8 14.9 0.049 12.5 14.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein V_ATPase_I PF01496.19 GAN10604.1 - 0.045 11.7 3.6 0.053 11.4 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adeno_VII PF03228.14 GAN10604.1 - 0.063 13.9 0.8 0.23 12.1 0.6 1.9 1 1 1 2 2 2 0 Adenoviral core protein VII Spc7 PF08317.11 GAN10604.1 - 0.074 11.9 11.4 0.13 11.2 11.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 GAN10604.1 - 0.11 13.1 13.4 0.69 10.4 6.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region LPP PF04728.13 GAN10604.1 - 0.15 12.5 2.7 5.2 7.5 0.2 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 GAN10604.1 - 0.15 12.4 11.2 0.56 10.7 3.9 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 GAN10604.1 - 0.23 11.7 10.0 0.35 11.1 3.4 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper GrpE PF01025.19 GAN10604.1 - 0.25 11.0 9.8 0.098 12.3 3.8 2.2 2 0 0 2 2 2 0 GrpE DivIC PF04977.15 GAN10604.1 - 0.29 10.9 18.9 0.04 13.7 7.4 2.9 2 1 1 3 3 3 0 Septum formation initiator Mt_ATP-synt_D PF05873.12 GAN10604.1 - 0.29 11.0 6.7 1.1 9.1 3.2 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF724 PF05266.14 GAN10604.1 - 0.33 10.7 14.8 0.11 12.3 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) XhlA PF10779.9 GAN10604.1 - 0.39 11.0 10.9 1.1 9.5 0.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA VRP3 PF03536.15 GAN10604.1 - 0.46 10.0 4.1 6.1 6.3 0.3 2.3 1 1 1 2 2 2 0 Salmonella virulence-associated 28kDa protein Baculo_PEP_C PF04513.12 GAN10604.1 - 0.67 10.0 9.6 0.48 10.5 3.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4558 PF15104.6 GAN10604.1 - 0.85 9.7 10.7 2.1 8.5 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) DUF2130 PF09903.9 GAN10604.1 - 0.86 8.8 13.8 13 5.0 13.8 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Bap31_Bap29_C PF18035.1 GAN10604.1 - 0.87 9.6 16.8 6.1 6.9 2.2 3.2 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain bZIP_1 PF00170.21 GAN10604.1 - 0.88 9.7 12.8 1.1 9.5 6.0 2.8 2 1 1 3 3 3 0 bZIP transcription factor DUF1451 PF07295.11 GAN10604.1 - 0.9 9.6 8.0 1 9.4 6.8 1.6 1 1 1 2 2 2 0 Zinc-ribbon containing domain YabA PF06156.13 GAN10604.1 - 0.91 10.2 12.1 0.5 11.0 4.8 2.3 1 1 0 2 2 2 0 Initiation control protein YabA COG5 PF10392.9 GAN10604.1 - 1 9.5 9.7 2.7 8.2 8.4 2.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 MbeB_N PF04837.12 GAN10604.1 - 1.2 9.5 12.1 0.67 10.3 2.4 2.9 2 1 1 3 3 2 0 MbeB-like, N-term conserved region eIF-4B PF06273.11 GAN10604.1 - 1.2 8.1 9.3 1.5 7.8 9.3 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B bZIP_2 PF07716.15 GAN10604.1 - 1.7 8.8 15.5 4 7.6 6.0 3.3 2 1 1 3 3 3 0 Basic region leucine zipper RPW8 PF05659.11 GAN10604.1 - 1.8 8.3 10.7 1 9.0 5.3 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fungal_TACC PF12709.7 GAN10604.1 - 1.9 9.0 13.7 9.8 6.7 5.8 2.9 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Rootletin PF15035.6 GAN10604.1 - 2 8.4 15.2 13 5.7 15.3 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Occludin_ELL PF07303.13 GAN10604.1 - 2.3 9.0 10.2 1.8 9.4 4.1 2.3 1 1 1 2 2 2 0 Occludin homology domain FIVAR PF07554.13 GAN10604.1 - 3.2 8.6 8.6 0.41 11.4 2.7 2.2 2 0 0 2 2 2 0 FIVAR domain Bcr-Abl_Oligo PF09036.10 GAN10604.1 - 4.2 7.4 7.9 2.7 8.1 3.2 2.5 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Ax_dynein_light PF10211.9 GAN10604.1 - 5 7.0 19.0 4.9 7.0 9.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1843 PF08898.10 GAN10604.1 - 6 7.4 7.8 4.3 7.9 3.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) MCU PF04678.13 GAN10604.1 - 6.3 6.9 10.5 7.6 6.6 4.2 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter PEP-utilisers_N PF05524.13 GAN10604.1 - 6.7 6.9 8.9 5.9e+02 0.6 8.9 2.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Tho2 PF11262.8 GAN10604.1 - 7.9 5.6 12.8 41 3.2 12.8 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Vps51 PF08700.11 GAN10604.1 - 8.2 6.6 12.1 8.3 6.6 2.7 3.6 2 1 1 3 3 3 0 Vps51/Vps67 V-ATPase_H_N PF03224.14 GAN10605.1 - 1.8e-86 290.3 7.5 1.8e-86 290.3 7.5 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 GAN10605.1 - 9.4e-43 145.0 6.2 6e-42 142.5 0.3 3.3 2 1 1 3 3 3 1 V-ATPase subunit H Arm PF00514.23 GAN10605.1 - 0.00011 22.1 0.0 2.1 8.5 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAN10605.1 - 0.002 18.5 0.5 0.13 12.7 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 GAN10605.1 - 0.03 14.6 0.4 0.92 9.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Terminase_2 PF03592.16 GAN10605.1 - 0.032 14.7 3.7 2.2 8.7 0.4 3.2 3 0 0 3 3 3 0 Terminase small subunit LemA PF04011.12 GAN10605.1 - 0.11 12.4 0.6 0.28 11.0 0.2 1.9 2 0 0 2 2 2 0 LemA family Stc1 PF12898.7 GAN10606.1 - 4e-13 49.7 11.6 4e-13 49.7 11.6 1.9 1 1 1 2 2 2 1 Stc1 domain RecR PF02132.15 GAN10606.1 - 0.015 14.9 3.6 0.015 14.9 3.6 2.6 3 0 0 3 3 3 0 RecR protein Elf1 PF05129.13 GAN10606.1 - 0.18 11.9 15.6 1.9 8.6 8.9 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_12 PF18658.1 GAN10606.1 - 0.47 10.1 4.2 0.45 10.1 0.2 2.5 1 1 2 3 3 3 0 Zinc-finger C2H2-type zf-RING_5 PF14634.6 GAN10606.1 - 0.6 10.1 12.5 3.7 7.6 4.1 2.9 3 0 0 3 3 3 0 zinc-RING finger domain PolC_DP2 PF03833.13 GAN10606.1 - 0.85 7.4 7.0 0.88 7.3 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CHY PF05495.12 GAN10606.1 - 0.95 10.0 13.2 3.8 8.1 13.2 1.9 1 1 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.12 GAN10606.1 - 1.2 9.1 13.9 1.6 8.7 5.8 2.7 1 1 1 2 2 2 0 zinc-ribbons zf-Sec23_Sec24 PF04810.15 GAN10606.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.7 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger Citrate_synt PF00285.21 GAN10607.1 - 6e-104 348.0 0.0 8.7e-104 347.4 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain SH3_1 PF00018.28 GAN10608.1 - 7.2e-11 41.5 0.0 1.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAN10608.1 - 1.5e-09 37.4 0.0 2.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAN10608.1 - 4.2e-09 36.1 0.0 7.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF5357 PF17310.2 GAN10608.1 - 0.22 10.1 1.1 0.31 9.6 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Peptidase_M17 PF00883.21 GAN10609.1 - 2.6e-122 408.0 0.1 3.4e-122 407.6 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 GAN10609.1 - 4.8e-14 52.3 1.5 8.2e-14 51.6 1.5 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Mitofilin PF09731.9 GAN10610.1 - 1.1e-81 275.6 43.0 1.3e-70 239.0 39.3 2.7 1 1 0 2 2 2 2 Mitochondrial inner membrane protein Tape_meas_lam_C PF09718.10 GAN10610.1 - 0.019 15.1 2.5 0.079 13.1 0.7 2.6 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ApoO PF09769.9 GAN10610.1 - 0.054 13.4 5.7 2.8 7.9 1.5 3.1 2 1 1 3 3 3 0 Apolipoprotein O Abi_C PF14355.6 GAN10610.1 - 0.16 12.1 1.9 1.9 8.6 0.0 3.4 2 1 1 3 3 3 0 Abortive infection C-terminus DUF3584 PF12128.8 GAN10610.1 - 0.38 8.2 33.3 0.72 7.3 25.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 GAN10610.1 - 1.1 9.4 21.5 5.2 7.2 14.0 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 GAN10610.1 - 4.4 7.9 18.0 5.6 7.6 0.2 4.2 3 0 0 3 3 3 0 YtxH-like protein Baculo_PEP_C PF04513.12 GAN10610.1 - 7.5 6.6 17.7 1 9.4 4.6 4.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_p24 PF05073.12 GAN10610.1 - 9.3 6.0 13.4 32 4.2 7.7 3.1 2 1 1 3 3 3 0 Baculovirus P24 capsid protein rve PF00665.26 GAN10611.1 - 0.00068 19.8 0.1 0.0048 17.1 0.0 2.2 1 1 1 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GAN10611.1 - 0.023 14.8 1.5 0.082 13.0 1.5 2.0 1 1 0 1 1 1 0 Integrase zinc binding domain Npun_R1517 PF18068.1 GAN10612.1 - 0.021 15.2 0.5 3.7 7.9 0.2 2.5 1 1 1 2 2 2 0 Npun R1517 PKcGMP_CC PF16808.5 GAN10612.1 - 0.95 9.4 8.0 1.7 8.5 3.1 3.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-HC5HC2H_2 PF13832.6 GAN10613.1 - 2.8e-32 111.2 11.2 2.8e-32 111.2 11.2 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 GAN10613.1 - 2.5e-26 92.9 9.2 2.5e-26 92.9 9.2 5.9 3 3 0 3 3 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 GAN10613.1 - 1.1e-25 89.7 16.8 1.8e-25 89.0 9.1 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 GAN10613.1 - 2.1e-20 72.5 0.9 2.1e-20 72.5 0.9 2.0 2 0 0 2 2 2 1 Bromodomain MIS13 PF08202.11 GAN10613.1 - 8.2e-15 54.9 4.4 8.2e-15 54.9 4.4 3.1 2 0 0 2 2 2 1 Mis12-Mtw1 protein family PHD_2 PF13831.6 GAN10613.1 - 1.4e-14 53.3 3.5 1.4e-14 53.3 3.5 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 GAN10613.1 - 3.6e-11 42.8 23.2 1.9e-10 40.4 6.0 2.9 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.17 GAN10613.1 - 2.7e-05 24.5 0.3 0.00042 20.7 0.0 3.1 2 0 0 2 2 2 1 PWWP domain C1_1 PF00130.22 GAN10613.1 - 0.035 14.0 0.2 0.035 14.0 0.2 2.6 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 GAN10613.1 - 0.79 9.7 19.3 0.14 12.1 5.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 GAN10613.1 - 2.2 7.9 13.5 0.047 13.3 3.3 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 GAN10613.1 - 4.9 7.6 15.2 3 8.2 2.1 2.9 2 0 0 2 2 2 0 C1 domain PRR20 PF15708.5 GAN10613.1 - 5 7.0 12.9 2.4 8.0 8.6 2.6 2 0 0 2 2 2 0 Proline-rich protein family 20 NPL PF17800.1 GAN10614.1 - 2.5e-11 44.1 0.0 2.5e-11 44.1 0.0 2.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain BUD22 PF09073.10 GAN10614.1 - 4 6.7 8.2 4.6 6.5 8.2 1.1 1 0 0 1 1 1 0 BUD22 Glu_synthase PF01645.17 GAN10615.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase CM_2 PF01817.21 GAN10616.1 - 9.2e-05 22.7 0.7 0.03 14.7 0.0 2.5 2 1 0 2 2 2 2 Chorismate mutase type II DUF3605 PF12239.8 GAN10617.1 - 1e-27 97.4 2.1 4.9e-26 91.9 2.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Ysc84 PF04366.12 GAN10618.1 - 5.3e-45 152.3 0.5 8.5e-45 151.6 0.5 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 GAN10618.1 - 2.7e-16 58.9 0.3 6.5e-16 57.7 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAN10618.1 - 6.7e-16 57.9 0.0 1.4e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN10618.1 - 6.1e-11 41.8 0.0 1.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4 PF00097.25 GAN10619.1 - 1.6e-07 31.1 9.1 3.1e-07 30.2 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN10619.1 - 4.8e-07 29.5 5.8 7.9e-07 28.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN10619.1 - 8.9e-07 28.7 5.8 7.1e-05 22.6 7.9 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN10619.1 - 9.3e-07 28.8 6.1 9.3e-07 28.8 6.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAN10619.1 - 1.1e-06 28.8 9.2 2.8e-06 27.5 9.2 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAN10619.1 - 8.6e-06 25.6 6.7 1.9e-05 24.5 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.20 GAN10619.1 - 0.0035 17.0 10.5 0.014 15.1 10.6 2.0 1 1 1 2 2 2 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 GAN10619.1 - 0.0044 17.2 8.7 0.011 15.8 8.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAN10619.1 - 0.005 16.7 7.7 0.019 14.8 7.7 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAN10619.1 - 0.009 16.0 1.9 0.018 15.1 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FYDLN_acid PF09538.10 GAN10619.1 - 0.018 15.7 1.4 0.018 15.7 1.4 3.3 4 0 0 4 4 3 0 Protein of unknown function (FYDLN_acid) zf-rbx1 PF12678.7 GAN10619.1 - 0.037 14.3 5.7 0.093 13.0 5.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 GAN10619.1 - 0.055 13.6 1.2 0.14 12.3 1.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.8 GAN10619.1 - 0.26 11.1 5.9 0.88 9.4 6.2 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 GAN10619.1 - 1.6 8.6 7.3 4.9 7.0 4.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger ATP19 PF11022.8 GAN10620.1 - 9.2e-20 70.8 0.4 1e-19 70.6 0.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit K 2-oxoacid_dh PF00198.23 GAN10621.1 - 1.4e-83 279.9 0.1 1.9e-83 279.5 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAN10621.1 - 6.4e-19 67.6 0.5 1.3e-18 66.6 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAN10621.1 - 1.3e-15 57.4 0.4 3e-15 56.3 0.4 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAN10621.1 - 0.12 12.2 1.0 0.53 10.2 0.1 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like AcetylCoA_hyd_C PF13336.6 GAN10622.1 - 0.1 12.5 1.1 6.7 6.6 0.6 2.8 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain UQ_con PF00179.26 GAN10623.1 - 3.4e-48 162.9 0.0 4.8e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAN10623.1 - 0.00057 19.6 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAN10623.1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 UEV domain Terminase_4 PF05119.12 GAN10623.1 - 0.034 14.6 0.2 0.054 13.9 0.2 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit RWD PF05773.22 GAN10623.1 - 0.055 13.8 0.0 0.074 13.3 0.0 1.4 1 1 0 1 1 1 0 RWD domain SR-25 PF10500.9 GAN10623.1 - 0.3 10.7 9.7 0.39 10.3 9.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 GAN10623.1 - 1.2 9.5 11.9 17 5.8 0.0 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain F_bP_aldolase PF01116.20 GAN10624.1 - 1.3e-89 300.4 0.0 2.4e-89 299.6 0.0 1.5 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Lipase_3 PF01764.25 GAN10624.1 - 9e-14 51.5 0.0 1.9e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Phage_Orf51 PF06194.11 GAN10624.1 - 0.11 12.5 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Alpha_L_fucos PF01120.17 GAN10625.1 - 2.8e-90 303.3 8.1 3.8e-90 302.9 8.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase DUF2716 PF10898.8 GAN10628.1 - 0.16 12.3 1.5 0.27 11.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) zinc_ribbon_10 PF10058.9 GAN10629.1 - 0.17 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein An_peroxidase PF03098.15 GAN10630.1 - 1.3e-38 132.9 2.1 2.5e-14 52.7 0.6 4.3 2 1 1 3 3 3 3 Animal haem peroxidase Phosducin PF02114.16 GAN10630.1 - 0.26 10.2 1.2 1.7 7.5 1.0 2.0 2 0 0 2 2 2 0 Phosducin zf-C2H2 PF00096.26 GAN10631.1 - 0.0099 16.3 2.0 0.017 15.5 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF2951 PF11166.8 GAN10631.1 - 0.01 16.0 0.3 0.012 15.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) zf-C2H2_4 PF13894.6 GAN10631.1 - 0.028 15.2 0.7 0.054 14.3 0.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger ATPase PF06745.13 GAN10631.1 - 0.093 12.1 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 KaiC C1_4 PF07975.12 GAN10631.1 - 0.11 12.8 1.5 0.12 12.7 0.6 1.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-RING_7 PF02591.15 GAN10631.1 - 0.55 10.5 3.9 0.94 9.7 3.9 1.4 1 0 0 1 1 1 0 C4-type zinc ribbon domain UBA PF00627.31 GAN10632.1 - 9.9e-28 95.6 3.8 4.9e-16 58.3 0.2 3.1 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 GAN10632.1 - 6.8e-24 83.4 3.1 1.3e-23 82.5 3.1 1.5 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 GAN10632.1 - 7.3e-22 76.9 7.5 7.3e-22 76.9 7.5 2.0 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.8 GAN10632.1 - 1.2e-07 31.4 4.5 2.5e-07 30.4 4.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 GAN10632.1 - 4.4e-05 23.2 0.0 0.21 11.4 0.0 2.6 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF1421 PF07223.11 GAN10632.1 - 0.005 16.7 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 UBA-like domain (DUF1421) TFIIA PF03153.13 GAN10632.1 - 0.0085 16.1 22.7 0.012 15.7 22.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ubiquitin_2 PF14560.6 GAN10632.1 - 0.013 16.0 0.3 0.033 14.6 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAN10632.1 - 0.027 14.6 0.1 0.09 12.9 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAN10632.1 - 0.067 13.6 1.3 0.18 12.2 1.3 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain S4 PF01479.25 GAN10632.1 - 0.17 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 S4 domain Pox_A12 PF04651.13 GAN10632.1 - 0.82 9.7 8.9 0.2 11.7 0.6 2.9 2 1 1 3 3 3 0 Poxvirus A12 protein DUF4168 PF13767.6 GAN10632.1 - 0.98 10.6 11.0 6.4 8.0 11.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) NAP PF00956.18 GAN10633.1 - 1.4e-93 313.0 8.4 1.4e-93 313.0 8.4 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 GAN10633.1 - 0.61 9.8 19.5 0.12 12.1 11.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.22 GAN10634.1 - 2.7e-21 75.1 0.8 4.4e-15 55.3 0.1 4.3 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN10634.1 - 3.9e-05 23.4 0.0 0.074 12.9 0.0 2.8 2 1 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAN10634.1 - 0.0003 20.7 0.5 6.7 6.8 0.0 3.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAN10634.1 - 0.016 15.3 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif RL PF17797.1 GAN10634.1 - 0.13 12.3 0.2 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 RL domain FERM_N_2 PF18038.1 GAN10635.1 - 0.016 16.0 0.9 2.9 8.8 0.1 2.5 2 0 0 2 2 2 0 FERM N-terminal domain COQ9 PF08511.11 GAN10636.1 - 9.2e-31 105.5 1.5 1.1e-30 105.2 1.5 1.1 1 0 0 1 1 1 1 COQ9 Peptidase_M16_M PF16187.5 GAN10637.1 - 1.5e-94 316.5 2.0 2.4e-94 315.8 2.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAN10637.1 - 5.4e-42 143.3 0.0 1.4e-41 141.9 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAN10637.1 - 1.9e-33 116.0 0.0 1.8e-24 86.8 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF4363 PF14276.6 GAN10637.1 - 0.025 14.7 2.9 0.092 12.9 2.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) AMP-binding PF00501.28 GAN10638.1 - 5.2e-72 242.7 0.0 7.2e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN10638.1 - 7.9e-14 52.4 0.2 1.4e-13 51.6 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SOG2 PF10428.9 GAN10639.1 - 0.47 9.6 5.1 0.55 9.4 5.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Myb_DNA-bind_5 PF13873.6 GAN10640.1 - 3.8e-05 23.7 0.5 3.8e-05 23.7 0.5 2.3 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAN10640.1 - 0.00018 21.8 5.5 0.00026 21.3 0.1 2.8 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 GAN10640.1 - 0.055 14.5 0.1 0.055 14.5 0.1 2.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Peptidase_A25 PF03418.14 GAN10640.1 - 1.5 7.7 4.9 2.1 7.1 4.9 1.2 1 0 0 1 1 1 0 Germination protease Cdh1_DBD_1 PF18196.1 GAN10640.1 - 7.2 7.0 9.2 2 8.7 0.9 2.8 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF3347 PF11827.8 GAN10640.1 - 8 6.6 15.7 0.82 9.8 10.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Cpn60_TCP1 PF00118.24 GAN10641.1 - 5.8e-169 562.8 3.4 6.6e-169 562.6 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 GAN10642.1 - 1e-76 257.8 0.0 1.2e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10642.1 - 4.2e-37 127.8 0.0 5.3e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAN10642.1 - 9.2e-05 21.5 0.0 0.00084 18.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN10642.1 - 0.00015 21.2 0.1 0.00069 19.0 0.1 2.0 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 GAN10642.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 GAN10642.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cytochrom_B561 PF03188.16 GAN10642.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF4472 PF14739.6 GAN10643.1 - 0.011 16.5 0.6 0.011 16.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) ZapB PF06005.12 GAN10643.1 - 0.019 15.4 5.4 0.023 15.1 5.4 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF4140 PF13600.6 GAN10643.1 - 0.049 14.1 1.3 0.059 13.8 1.3 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FapA PF03961.13 GAN10643.1 - 0.087 11.4 0.2 0.091 11.4 0.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 GAN10643.1 - 0.22 11.3 3.0 0.28 11.0 3.0 1.2 1 0 0 1 1 1 0 Septum formation initiator MMS1_N PF10433.9 GAN10644.1 - 3.9e-60 203.9 1.1 3.9e-60 203.9 1.1 2.0 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAN10644.1 - 2.2e-52 178.4 0.1 1.3e-50 172.5 0.1 2.5 2 0 0 2 2 2 1 CPSF A subunit region TilS_C PF11734.8 GAN10644.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 TilS substrate C-terminal domain DUF3490 PF11995.8 GAN10644.1 - 0.13 12.0 1.4 3.4 7.5 1.4 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) RabGAP-TBC PF00566.18 GAN10645.1 - 4.3e-32 111.5 8.3 5.5e-17 62.1 3.3 3.2 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Peptidase_M3 PF01432.20 GAN10646.1 - 5.5e-125 418.2 0.0 7.9e-125 417.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 EF-hand_4 PF12763.7 GAN10647.1 - 7.4e-29 99.8 0.1 2.5e-18 65.9 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GAN10647.1 - 2.1e-05 23.7 0.0 0.026 14.1 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAN10647.1 - 0.0003 21.2 0.0 0.06 13.8 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair DUF1720 PF08226.11 GAN10647.1 - 0.0041 17.5 29.1 0.05 14.0 29.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1720) APG6_N PF17675.1 GAN10647.1 - 0.0052 17.3 2.2 0.0052 17.3 2.2 2.8 3 0 0 3 3 3 1 Apg6 coiled-coil region EF-hand_6 PF13405.6 GAN10647.1 - 0.01 15.7 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 GAN10647.1 - 0.034 14.5 0.0 0.083 13.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 GAN10647.1 - 0.15 12.0 0.0 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair E3_binding PF02817.17 GAN10647.1 - 0.16 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 e3 binding domain Atg14 PF10186.9 GAN10647.1 - 1.2 8.1 12.3 0.015 14.4 1.9 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 GAN10647.1 - 4.7 5.0 4.9 2.6 5.9 0.6 2.3 2 0 0 2 2 2 0 Prominin Polysacc_deac_1 PF01522.21 GAN10648.1 - 1.5e-22 79.8 0.0 3.1e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Mucin PF01456.17 GAN10648.1 - 0.47 10.4 57.7 0.022 14.7 50.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein RNA_pol_Rpc4 PF05132.14 GAN10648.1 - 0.66 10.4 7.2 0.042 14.3 1.8 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 Dicty_REP PF05086.12 GAN10648.1 - 4.8 5.0 18.9 6.6 4.6 18.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 GAN10649.1 - 6.3e-74 248.7 0.0 7.3e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10649.1 - 1.2e-30 106.6 0.0 2e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN10649.1 - 0.028 14.4 0.2 0.044 13.7 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN10649.1 - 0.051 12.9 0.0 0.15 11.3 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 GAN10649.1 - 0.098 11.7 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Stc1 PF12898.7 GAN10650.1 - 1.5e-24 86.4 18.0 3.9e-20 72.2 14.1 1.9 1 1 1 2 2 2 2 Stc1 domain DUF938 PF06080.12 GAN10650.1 - 0.067 12.9 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) zf-CRD PF17979.1 GAN10650.1 - 0.27 11.3 9.6 0.14 12.3 7.2 1.8 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions FYVE_2 PF02318.16 GAN10650.1 - 0.9 9.8 8.5 4.2 7.6 6.7 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger PolC_DP2 PF03833.13 GAN10650.1 - 2.4 5.9 5.6 2.6 5.8 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_12 PF11331.8 GAN10650.1 - 9.2 6.2 11.3 1.6 8.6 2.9 2.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-CHY PF05495.12 GAN10650.1 - 9.9 6.7 14.2 1.8e+02 2.7 12.6 2.8 1 1 2 3 3 3 0 CHY zinc finger Pyr_redox_2 PF07992.14 GAN10651.1 - 1.3e-45 155.9 0.0 2.3e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 GAN10651.1 - 5.2e-17 62.0 6.8 1.4e-09 38.2 0.9 2.8 1 1 2 3 3 3 3 EF-hand domain pair Pyr_redox PF00070.27 GAN10651.1 - 3.1e-14 53.3 0.1 2.8e-10 40.6 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 GAN10651.1 - 1.3e-11 43.5 1.0 9.4e-05 22.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAN10651.1 - 1.3e-11 43.2 3.4 2.1e-05 23.7 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAN10651.1 - 2.1e-08 33.3 0.2 0.0031 16.9 0.2 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.6 GAN10651.1 - 4e-06 26.3 0.5 0.12 11.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GAS PF13851.6 GAN10651.1 - 0.0025 17.2 1.8 0.0028 17.0 0.4 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding EF-hand_8 PF13833.6 GAN10651.1 - 0.0033 17.2 0.5 0.07 13.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAN10651.1 - 0.0068 16.7 1.8 0.34 11.3 0.0 3.0 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region NAD_binding_8 PF13450.6 GAN10651.1 - 0.029 14.6 0.0 31 4.9 0.0 3.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GCP_N_terminal PF17681.1 GAN10651.1 - 0.085 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal EF-hand_10 PF14788.6 GAN10651.1 - 0.19 11.6 0.5 13 5.7 0.1 2.5 2 0 0 2 2 2 0 EF hand NUC173 PF08161.12 GAN10652.1 - 0.058 13.1 0.2 0.071 12.8 0.2 1.1 1 0 0 1 1 1 0 NUC173 domain Kinesin PF00225.23 GAN10653.1 - 3.7e-76 256.2 1.2 3.7e-76 256.2 1.2 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN10653.1 - 0.00012 22.0 0.4 0.00093 19.2 0.0 2.8 2 0 0 2 2 2 1 Microtubule binding MFS_1 PF07690.16 GAN10654.1 - 1.5e-35 122.8 41.0 5.7e-24 84.7 18.1 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN10654.1 - 0.00049 19.1 15.7 0.00049 19.1 15.7 4.6 3 3 0 3 3 3 1 Sugar (and other) transporter Ribosomal_S7 PF00177.21 GAN10655.1 - 1.3e-35 122.3 1.2 2.1e-35 121.6 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FSA_C PF10479.9 GAN10655.1 - 0.0053 15.0 4.9 0.0074 14.5 4.9 1.2 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus Herpes_Helicase PF02689.14 GAN10656.1 - 1.2e-06 26.8 0.0 1.3e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Helicase Neuraminidase PF18413.1 GAN10656.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Neuraminidase-like domain PPR_2 PF13041.6 GAN10657.1 - 8.6e-55 182.7 21.6 1.5e-10 41.1 0.2 9.8 4 2 5 10 10 10 7 PPR repeat family PPR PF01535.20 GAN10657.1 - 3.2e-41 136.7 13.3 1.5e-05 24.9 0.0 11.1 11 0 0 11 11 11 7 PPR repeat PPR_1 PF12854.7 GAN10657.1 - 2.7e-40 135.8 3.0 4e-05 23.2 0.0 9.5 9 0 0 9 9 9 9 PPR repeat PPR_3 PF13812.6 GAN10657.1 - 2.8e-35 120.2 12.8 1.9e-08 34.2 0.0 7.4 5 3 3 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 GAN10657.1 - 2.1e-17 63.2 0.1 6.5e-05 22.4 0.0 4.5 2 2 4 6 6 6 4 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 GAN10657.1 - 7.1e-08 31.7 0.4 3.9e-05 22.7 0.0 3.3 2 1 0 3 3 3 1 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 GAN10657.1 - 4.2e-05 23.4 2.0 1.1 9.2 0.0 5.2 3 1 3 6 6 6 1 Mitochondrial ATPase expression RPM2 PF08579.11 GAN10657.1 - 0.0034 17.8 4.8 0.89 10.0 0.0 4.4 2 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ID PF18543.1 GAN10657.1 - 0.12 12.4 1.2 0.59 10.2 0.5 2.3 2 0 0 2 2 2 0 Intracellular delivery domain Suc_Fer-like PF06999.12 GAN10658.1 - 2e-58 197.5 0.0 2.4e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF460 PF04312.13 GAN10658.1 - 0.042 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DHR-2 PF06920.13 GAN10659.1 - 1.7e-110 370.2 2.0 1.7e-110 370.2 2.0 2.6 2 0 0 2 2 2 1 Dock homology region 2 DOCK_N PF16172.5 GAN10659.1 - 6.9e-107 357.6 2.3 1.1e-106 357.0 0.2 2.4 2 0 0 2 2 2 1 DOCK N-terminus DOCK-C2 PF14429.6 GAN10659.1 - 1.2e-39 136.2 14.0 2e-38 132.2 2.8 4.0 3 1 0 3 3 3 2 C2 domain in Dock180 and Zizimin proteins DUF5402 PF17393.2 GAN10659.1 - 0.2 11.6 0.1 0.53 10.2 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5402) DUF3475 PF11961.8 GAN10659.1 - 0.21 11.7 0.9 3.2 7.9 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) Methyltransf_16 PF10294.9 GAN10661.1 - 2.9e-29 102.0 1.4 7.9e-29 100.6 1.4 1.7 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAN10661.1 - 0.00025 20.6 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAN10661.1 - 0.00052 19.5 0.8 0.0008 18.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 GAN10661.1 - 0.0098 15.7 0.1 0.031 14.1 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAN10661.1 - 0.057 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PIN_4 PF13638.6 GAN10662.1 - 0.0024 18.1 0.9 0.0042 17.4 0.9 1.5 1 1 0 1 1 1 1 PIN domain EXS PF03124.14 GAN10663.1 - 4.8e-89 298.9 30.2 6.3e-89 298.6 30.2 1.2 1 0 0 1 1 1 1 EXS family Ribosomal_L30_N PF08079.12 GAN10663.1 - 3e-23 81.9 16.1 6.2e-23 80.8 16.1 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain SPX PF03105.19 GAN10663.1 - 4.2e-20 73.0 0.3 4.2e-20 73.0 0.3 2.0 2 0 0 2 2 2 1 SPX domain Ribosomal_L30 PF00327.20 GAN10663.1 - 2e-17 62.8 1.7 4.1e-17 61.8 1.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e NOA36 PF06524.12 GAN10663.1 - 1.6 8.0 4.5 2.8 7.2 4.5 1.3 1 0 0 1 1 1 0 NOA36 protein Opi1 PF08618.10 GAN10665.1 - 4.4e-68 230.4 18.7 1.5e-49 169.4 6.7 4.0 2 1 2 4 4 4 3 Transcription factor Opi1 Perilipin PF03036.16 GAN10665.1 - 6.9e-07 28.6 1.2 2e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 Perilipin family Ipi1_N PF12333.8 GAN10665.1 - 2.2 8.9 4.7 0.46 11.1 0.4 2.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF1640 PF07798.11 GAN10666.1 - 3.5e-57 193.3 12.2 4.7e-57 192.9 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) zf-U1 PF06220.12 GAN10666.1 - 4.9e-07 29.4 2.6 1e-06 28.4 2.6 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-CCCH PF00642.24 GAN10666.1 - 0.00097 19.0 2.8 0.0018 18.2 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HALZ PF02183.18 GAN10666.1 - 0.015 15.5 2.9 0.068 13.4 2.9 2.2 1 1 0 1 1 1 0 Homeobox associated leucine zipper zf-CCCH_4 PF18044.1 GAN10666.1 - 0.14 11.9 4.9 0.31 10.9 4.9 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAN10666.1 - 0.15 12.2 5.5 0.3 11.2 5.5 1.5 1 0 0 1 1 1 0 Zinc finger domain XhlA PF10779.9 GAN10666.1 - 0.62 10.3 3.2 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Uso1_p115_C PF04871.13 GAN10666.1 - 1.1 9.7 11.0 1 9.8 5.8 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 GAN10666.1 - 3.4 6.7 9.3 6.1 5.8 8.6 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 GAN10666.1 - 6.5 7.4 9.2 11 6.8 6.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CCDC23 PF15674.5 GAN10666.1 - 9.5 6.3 7.2 0.83 9.7 0.6 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 23 zf-rbx1 PF12678.7 GAN10667.1 - 4.4e-25 87.7 13.0 6.1e-25 87.3 13.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAN10667.1 - 1.2e-16 60.5 10.8 1.7e-16 60.1 10.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GAN10667.1 - 2.5e-06 27.7 14.5 9e-05 22.7 14.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAN10667.1 - 0.001 18.9 11.7 0.018 14.9 11.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAN10667.1 - 0.0019 18.0 14.6 0.0029 17.4 9.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN10667.1 - 0.12 12.3 10.7 0.34 10.8 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN10667.1 - 0.33 10.7 15.8 27 4.6 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 GAN10667.1 - 0.52 10.4 7.6 2 8.5 7.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 GAN10667.1 - 0.58 10.4 9.3 2.9 8.1 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAN10667.1 - 1.2 8.8 15.0 0.3 10.7 4.9 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAN10667.1 - 6.5 6.8 12.1 55 3.8 12.1 2.5 1 1 0 1 1 1 0 zinc-RING finger domain Asp PF00026.23 GAN10668.1 - 5.2e-41 141.1 3.9 6.7e-20 71.7 1.7 2.1 1 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN10668.1 - 2.7e-07 31.0 7.2 0.00048 20.4 0.3 3.2 2 1 2 4 4 4 2 Xylanase inhibitor N-terminal ThiF PF00899.21 GAN10669.1 - 3.4e-33 115.0 0.0 4.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family zf-H2C2_2 PF13465.6 GAN10670.1 - 1.1e-06 28.8 1.3 1.1e-06 28.8 1.3 2.4 2 0 0 2 2 2 1 Zinc-finger double domain CLP1_P PF16575.5 GAN10671.1 - 6.9e-40 136.9 0.0 1.4e-39 135.9 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Pro_CA PF00484.19 GAN10672.1 - 5.9e-51 172.9 0.6 8.3e-51 172.4 0.6 1.2 1 0 0 1 1 1 1 Carbonic anhydrase TCO89 PF10452.9 GAN10673.1 - 6e-09 35.4 5.2 6e-09 35.4 5.2 2.2 3 0 0 3 3 3 1 TORC1 subunit TCO89 Peptidase_M13_N PF05649.13 GAN10674.1 - 3.3e-85 287.1 0.9 4.6e-85 286.6 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAN10674.1 - 4e-72 242.1 0.1 6.7e-72 241.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF1154 PF06631.11 GAN10675.1 - 6.5 6.9 7.8 0.45 10.6 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Peptidase_C97 PF05903.14 GAN10676.1 - 2.3e-37 128.2 0.2 1.4e-36 125.6 0.0 1.9 2 0 0 2 2 2 1 PPPDE putative peptidase domain FAM176 PF14851.6 GAN10676.1 - 0.047 13.3 2.3 0.072 12.8 2.3 1.2 1 0 0 1 1 1 0 FAM176 family PI3K_1B_p101 PF10486.9 GAN10676.1 - 0.14 9.9 0.8 0.19 9.5 0.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HSF_DNA-bind PF00447.17 GAN10677.1 - 4e-24 85.0 2.0 4e-24 85.0 2.0 2.2 3 0 0 3 3 3 1 HSF-type DNA-binding TFIIA PF03153.13 GAN10677.1 - 0.015 15.3 13.0 0.018 15.1 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UL42 PF17638.2 GAN10677.1 - 0.066 13.2 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 HCMV UL42 Spem1 PF15670.5 GAN10677.1 - 0.081 12.5 9.9 0.15 11.6 9.9 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 PIP5K PF01504.18 GAN10677.1 - 0.65 9.2 9.2 0.51 9.5 0.1 2.2 2 1 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4407 PF14362.6 GAN10677.1 - 1.9 7.8 5.4 2.8 7.2 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hydin_ADK PF17213.3 GAN10677.1 - 2.9 8.1 7.8 15 5.8 4.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Bap31 PF05529.12 GAN10678.1 - 1.8e-32 112.0 1.3 2.6e-32 111.5 1.3 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region PS_Dcarbxylase PF02666.15 GAN10679.1 - 3.7e-52 176.8 0.0 8.2e-52 175.7 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase MetOD2 PF18548.1 GAN10680.1 - 0.14 12.3 1.7 0.38 10.9 1.7 1.8 1 0 0 1 1 1 0 Metanogen output domain 2 UPF0014 PF03649.13 GAN10681.1 - 2.3e-73 246.5 25.2 2.7e-73 246.3 25.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Ost5 PF05251.12 GAN10681.1 - 0.03 14.6 0.9 0.03 14.6 0.9 3.1 4 1 0 4 4 4 0 Oligosaccharyltransferase subunit 5 DSPc PF00782.20 GAN10682.1 - 8.6e-26 90.3 1.6 1.5e-25 89.6 0.5 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 GAN10682.1 - 1.3e-09 38.5 0.1 4.1e-07 30.5 0.0 3.4 2 2 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 GAN10682.1 - 0.00021 20.9 0.1 0.00055 19.6 0.1 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAN10682.1 - 0.0088 16.2 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 GAN10682.1 - 0.0088 15.6 1.4 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 GAN10682.1 - 0.022 15.1 0.0 0.069 13.4 0.0 1.9 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF3326 PF11805.8 GAN10682.1 - 0.052 12.4 0.1 0.08 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) zf-C3H1 PF10650.9 GAN10683.1 - 4.7e-11 42.2 0.3 7.9e-11 41.5 0.3 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Defensin_3 PF08131.11 GAN10683.1 - 0.065 13.4 1.3 0.09 13.0 0.5 1.7 2 0 0 2 2 2 0 Defensin-like peptide family CAP_N PF01213.19 GAN10683.1 - 1 8.8 2.2 1.2 8.6 2.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4472 PF14739.6 GAN10684.1 - 0.89 10.3 6.5 0.48 11.2 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) DUF5394 PF17372.2 GAN10684.1 - 3.2 7.2 10.8 0.56 9.7 1.9 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5394) IF4E PF01652.18 GAN10685.1 - 2.7e-58 196.3 0.7 3.1e-58 196.1 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2590 PF10761.9 GAN10686.1 - 0.16 12.1 2.2 0.31 11.2 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) Ada3 PF10198.9 GAN10686.1 - 6.6 6.9 10.6 1.2 9.3 6.4 1.8 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 RXT2_N PF08595.11 GAN10687.1 - 1.1e-11 45.0 0.7 1.1e-11 45.0 0.7 3.0 2 2 0 2 2 2 1 RXT2-like, N-terminal Peroxin-3 PF04882.12 GAN10687.1 - 0.13 11.2 9.5 0.2 10.6 9.5 1.3 1 0 0 1 1 1 0 Peroxin-3 Crystallin PF00525.18 GAN10688.1 - 0.04 14.1 0.0 0.04 14.1 0.0 2.3 3 0 0 3 3 3 0 Alpha crystallin A chain, N terminal zf-C2H2 PF00096.26 GAN10689.1 - 1.4e-09 37.9 23.8 0.00012 22.3 1.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN10689.1 - 2.1e-08 34.3 22.2 0.0037 18.0 1.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN10689.1 - 1.7e-07 31.3 25.0 0.0004 20.7 4.5 5.1 5 0 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 GAN10689.1 - 0.00065 20.3 6.3 0.36 11.5 0.8 2.5 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 GAN10689.1 - 0.0034 17.1 20.1 0.087 12.6 0.1 4.8 4 0 0 4 4 4 3 C2H2-type zinc-finger domain PRA-CH PF01502.18 GAN10689.1 - 0.031 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase zf-C2H2_6 PF13912.6 GAN10689.1 - 0.98 9.5 6.4 0.98 9.5 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Arf PF00025.21 GAN10690.1 - 9.1e-66 220.6 0.0 1e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAN10690.1 - 2e-09 37.1 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAN10690.1 - 2.6e-09 36.7 0.0 8.8e-06 25.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAN10690.1 - 2e-07 31.3 0.0 4.5e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN10690.1 - 3e-07 30.2 0.0 3.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAN10690.1 - 6.8e-07 29.4 0.0 1.4e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAN10690.1 - 5.4e-06 25.9 0.0 6.2e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 GAN10690.1 - 0.041 13.6 0.0 0.13 12.0 0.0 1.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Actin PF00022.19 GAN10691.1 - 3.7e-49 167.4 0.0 1.8e-48 165.2 0.0 2.0 1 1 1 2 2 2 1 Actin MreB_Mbl PF06723.13 GAN10691.1 - 3.5e-12 45.8 0.0 1e-09 37.7 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 GAN10691.1 - 0.015 15.7 0.4 0.35 11.3 0.0 2.6 2 1 0 2 2 2 0 Cell division protein FtsA Exo_endo_phos PF03372.23 GAN10692.1 - 5.9e-11 42.3 0.0 9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 GAN10692.1 - 9.5e-08 32.0 0.0 3.5e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.6 GAN10692.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like DFRP_C PF16543.5 GAN10693.1 - 7.3e-29 100.1 2.4 7.3e-29 100.1 2.4 4.1 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 GAN10693.1 - 6.1e-08 32.4 0.6 6.1e-08 32.4 0.6 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAN10693.1 - 3.6e-07 29.8 9.3 2.4e-06 27.2 1.2 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAN10693.1 - 7.7e-06 25.8 15.8 8.5e-06 25.7 5.1 3.2 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 GAN10693.1 - 0.0036 18.0 27.4 0.18 12.6 14.5 4.8 3 1 1 4 4 4 2 Torus domain zf-CCCH_2 PF14608.6 GAN10693.1 - 0.05 14.1 2.3 0.05 14.1 2.3 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger IspA PF04279.15 GAN10694.1 - 0.0082 16.3 6.3 0.0082 16.3 6.3 2.4 1 1 2 3 3 3 1 Intracellular septation protein A DUF2681 PF10883.8 GAN10694.1 - 0.65 10.4 6.0 0.24 11.8 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3159 PF11361.8 GAN10694.1 - 1.9 8.2 14.1 6.7 6.4 14.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) PHO4 PF01384.20 GAN10694.1 - 2 7.4 5.5 4 6.4 5.5 1.6 1 1 0 1 1 1 0 Phosphate transporter family MerC PF03203.14 GAN10694.1 - 2.7 8.5 11.4 52 4.3 11.4 2.5 1 1 1 2 2 2 0 MerC mercury resistance protein CPSF73-100_C PF11718.8 GAN10695.1 - 6.6e-63 212.1 0.4 1.2e-62 211.3 0.4 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 GAN10695.1 - 1.7e-32 111.9 0.0 4.7e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 GAN10695.1 - 7.6e-18 64.6 0.1 6.6e-17 61.6 0.0 2.4 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 GAN10695.1 - 2.8e-17 62.4 0.0 7.3e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 GAN10695.1 - 5.9e-15 55.8 0.2 1.2e-14 54.8 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 GAN10695.1 - 2.3e-06 27.6 0.1 5.4e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GAN10695.1 - 0.00014 21.5 0.1 0.00052 19.6 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GAN10695.1 - 0.025 13.8 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative beta-lactamase-like family DUF530 PF04409.12 GAN10696.1 - 0.066 11.6 0.5 0.087 11.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) IF4E PF01652.18 GAN10697.1 - 6.6e-30 104.0 0.7 2.1e-29 102.3 0.4 2.0 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E DUF2024 PF09630.10 GAN10697.1 - 0.0035 17.2 0.4 0.83 9.6 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF2024) Nt_Gln_amidase PF09764.9 GAN10698.1 - 0.14 11.8 1.9 5.4 6.6 0.4 2.4 1 1 1 2 2 2 0 N-terminal glutamine amidase DUF2423 PF10338.9 GAN10700.1 - 2.5e-13 50.0 6.0 2.5e-13 50.0 6.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Voldacs PF03517.13 GAN10701.1 - 1.6e-26 93.1 2.1 1.6e-26 93.1 2.1 2.1 1 1 1 2 2 2 1 Regulator of volume decrease after cellular swelling GRAM PF02893.20 GAN10701.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Brr6_like_C_C PF10104.9 GAN10704.1 - 2.4e-41 140.6 5.9 3e-41 140.3 5.9 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Rab3-GTPase_cat PF13890.6 GAN10708.1 - 2.2e-57 193.2 0.8 6.9e-57 191.6 0.8 1.9 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Glycos_transf_2 PF00535.26 GAN10710.1 - 2.5e-34 118.6 0.0 3.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAN10710.1 - 1.1e-12 48.3 0.0 1.3e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAN10710.1 - 1.4e-05 24.7 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAN10710.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2834 PF11196.8 GAN10711.1 - 3.2e-10 40.2 23.1 1.8e-06 28.2 3.4 4.2 3 1 1 4 4 4 3 Protein of unknown function (DUF2834) PP2C PF00481.21 GAN10712.1 - 6.7e-13 48.9 0.0 2.8e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAN10712.1 - 1.4e-05 24.9 0.0 9.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C SDH_alpha PF03313.15 GAN10714.1 - 6.4e-105 350.5 0.1 8.7e-105 350.1 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 GAN10714.1 - 1.9e-58 197.2 0.1 6.4e-58 195.5 0.1 1.9 1 0 0 1 1 1 1 Serine dehydratase beta chain LSM PF01423.22 GAN10715.1 - 1.3e-18 66.5 0.3 2.2e-18 65.7 0.3 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAN10715.1 - 0.023 14.3 0.1 0.05 13.3 0.1 1.6 1 0 0 1 1 1 0 Hfq protein DUF3074 PF11274.8 GAN10717.1 - 3.8e-25 88.9 0.1 5.3e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Neurensin PF14927.6 GAN10718.1 - 0.0091 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Neurensin Asp-B-Hydro_N PF05279.11 GAN10718.1 - 0.24 11.5 5.9 0.46 10.5 5.9 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PH PF00169.29 GAN10719.1 - 7.9e-07 29.5 0.3 6.3e-06 26.6 0.1 2.7 2 1 0 2 2 2 1 PH domain TFIIA PF03153.13 GAN10719.1 - 2.2e-05 24.7 20.8 2.2e-05 24.7 20.8 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAN10719.1 - 7.9e-05 22.4 26.1 7.9e-05 22.4 26.1 2.8 3 0 0 3 3 3 2 Spt20 family LRR_1 PF00560.33 GAN10719.1 - 0.035 14.6 10.8 37 5.4 0.0 7.9 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 GAN10719.1 - 0.06 13.4 25.0 0.19 11.9 0.0 8.2 8 0 0 8 8 8 0 Leucine Rich repeat eIF-3_zeta PF05091.12 GAN10719.1 - 0.15 11.0 13.9 0.089 11.7 7.5 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4770 PF15994.5 GAN10719.1 - 0.89 9.8 16.9 0.044 14.0 10.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Jak1_Phl PF17887.1 GAN10719.1 - 1.9 8.4 16.8 2.9 7.8 1.8 3.2 3 0 0 3 3 3 0 Jak1 pleckstrin homology-like domain EPL1 PF10513.9 GAN10719.1 - 6.6 7.1 13.6 0.33 11.3 5.6 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like CCDC53 PF10152.9 GAN10719.1 - 7.4 7.0 17.0 0.087 13.2 7.5 2.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Peptidase_M16 PF00675.20 GAN10720.1 - 1.1e-55 187.7 0.3 9.5e-55 184.7 0.2 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAN10720.1 - 1.8e-40 138.9 0.0 4.4e-39 134.4 0.0 2.5 3 0 0 3 3 3 1 Peptidase M16 inactive domain DUF4853 PF16145.5 GAN10720.1 - 0.15 12.2 0.1 48 4.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4853) Pkinase PF00069.25 GAN10721.1 - 2.8e-76 256.4 0.0 3.8e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10721.1 - 4.9e-36 124.3 0.0 6.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN10721.1 - 3.4e-07 29.9 0.0 1.9e-06 27.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAN10721.1 - 4.4e-05 22.4 0.0 9.7e-05 21.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAN10721.1 - 0.0035 16.9 0.3 0.0066 16.0 0.1 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 GAN10721.1 - 0.019 14.3 1.1 0.02 14.3 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN10721.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 GAN10722.1 - 4.8e-10 39.9 1.9 0.0017 19.2 0.3 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.7 GAN10722.1 - 2.9e-08 33.5 0.6 8.7e-08 31.9 0.4 1.9 2 0 0 2 2 2 1 F-box-like MelC1 PF06236.11 GAN10722.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 F-box PF00646.33 GAN10722.1 - 0.034 14.0 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 F-box domain ARID PF01388.21 GAN10722.1 - 0.13 13.0 0.0 0.53 11.0 0.0 2.1 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain Elongin_A PF06881.11 GAN10722.1 - 2.5 8.7 4.6 1.3 9.6 1.7 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PH PF00169.29 GAN10723.1 - 3.3e-21 75.8 2.5 7.2e-21 74.7 1.3 2.2 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 GAN10723.1 - 1.3e-17 63.7 0.1 3e-17 62.5 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAN10723.1 - 7.2e-12 45.6 0.1 1.7e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 GAN10723.1 - 3.1e-10 39.7 0.1 7.1e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAN10723.1 - 2e-09 36.9 2.3 2.6e-09 36.6 0.4 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 GAN10723.1 - 3.4e-07 29.8 0.3 6.6e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 GAN10723.1 - 5.5e-06 26.8 5.7 5.5e-06 26.8 5.7 4.7 3 2 1 4 4 4 1 Pleckstrin homology domain SAM_Ste50p PF09235.10 GAN10723.1 - 1.4e-05 25.2 0.6 3.6e-05 23.9 0.6 1.7 1 0 0 1 1 1 1 Ste50p, sterile alpha motif DUF4746 PF15928.5 GAN10723.1 - 0.2 11.1 9.3 0.59 9.5 9.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PepSY_TM PF03929.16 GAN10723.1 - 6.3 6.4 12.9 98 2.5 0.0 2.5 2 0 0 2 2 2 0 PepSY-associated TM region PfkB PF00294.24 GAN10724.1 - 6.5e-59 199.7 1.8 7.9e-59 199.4 1.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAN10724.1 - 0.0058 16.0 0.0 0.035 13.5 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TPR_1 PF00515.28 GAN10725.1 - 2e-07 30.5 1.4 0.39 10.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10725.1 - 3.9e-07 29.7 0.5 0.43 10.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10725.1 - 1.3e-05 25.0 1.1 2.5 8.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_6 PF13516.6 GAN10725.1 - 1.9e-05 24.3 0.9 0.03 14.4 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat TPR_14 PF13428.6 GAN10725.1 - 0.00055 20.5 0.1 0.86 10.6 0.3 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 GAN10725.1 - 0.00055 19.8 0.0 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like TPR_16 PF13432.6 GAN10725.1 - 0.0024 18.5 0.1 0.5 11.1 0.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN10725.1 - 0.0025 17.7 0.0 0.9 9.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_4 PF12799.7 GAN10725.1 - 0.0037 17.7 2.8 1.7 9.2 0.1 4.0 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN10725.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_12 PF13424.6 GAN10725.1 - 0.017 15.4 0.2 1.2 9.4 0.4 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Dak2 PF02734.17 GAN10725.1 - 0.079 12.9 0.1 0.26 11.2 0.0 1.8 2 1 0 2 2 2 0 DAK2 domain TPR_11 PF13414.6 GAN10725.1 - 0.085 12.6 0.0 11 5.7 0.0 2.7 2 1 1 3 3 3 0 TPR repeat LRR_1 PF00560.33 GAN10725.1 - 0.3 11.8 3.6 16 6.5 0.0 4.6 5 0 0 5 5 4 0 Leucine Rich Repeat Arrestin_N PF00339.29 GAN10726.1 - 4e-11 43.2 0.0 5.1e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN10726.1 - 9.1e-05 22.9 0.6 0.0025 18.3 1.2 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF1752 PF08550.10 GAN10727.1 - 1.4e-10 40.8 2.3 3.7e-10 39.5 2.3 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) NOA36 PF06524.12 GAN10727.1 - 0.00067 19.1 3.6 0.00084 18.8 3.6 1.2 1 0 0 1 1 1 1 NOA36 protein MCM_bind PF09739.9 GAN10727.1 - 0.0073 14.8 3.7 0.0093 14.5 3.7 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor RXT2_N PF08595.11 GAN10727.1 - 0.021 14.9 3.3 0.031 14.3 3.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 GAN10727.1 - 0.32 11.4 8.6 0.52 10.7 8.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAN10727.1 - 0.37 11.2 5.5 0.68 10.3 5.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 GAN10727.1 - 0.86 7.6 4.9 1 7.4 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 GAN10727.1 - 3 7.5 9.6 2.4 7.8 8.3 1.5 1 1 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 GAN10727.1 - 4.5 7.0 10.2 7.5 6.3 10.2 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein WES_acyltransf PF03007.16 GAN10728.1 - 5.3e-20 72.3 0.1 2.9e-19 69.9 0.1 1.9 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 GAN10728.1 - 6.2e-13 48.9 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 GAN10728.1 - 1.1e-05 24.3 0.1 7.7e-05 21.5 0.1 2.0 2 0 0 2 2 2 1 Condensation domain CrgA PF06781.12 GAN10728.1 - 0.13 12.4 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Cell division protein CrgA zf-C2H2 PF00096.26 GAN10729.1 - 0.00042 20.6 14.7 0.0076 16.7 2.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 GAN10729.1 - 0.0017 18.7 5.1 0.0018 18.6 2.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAN10729.1 - 0.0035 17.3 1.9 0.0035 17.3 1.9 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAN10729.1 - 0.0044 17.8 14.1 0.0093 16.7 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN10729.1 - 0.0088 16.3 3.8 0.0088 16.3 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding BolA PF01722.18 GAN10729.1 - 0.55 10.6 1.9 1.1 9.6 1.9 1.4 1 0 0 1 1 1 0 BolA-like protein zf-H2C2_2 PF13465.6 GAN10729.1 - 2 9.0 16.1 1.6 9.3 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Sterol_MT_C PF08498.10 GAN10730.1 - 3.6e-27 94.5 0.5 5.9e-27 93.8 0.5 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAN10730.1 - 3.6e-19 69.2 0.0 1.3e-18 67.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN10730.1 - 2.5e-17 63.3 0.0 9.1e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GAN10730.1 - 1.1e-15 57.7 0.0 1.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 GAN10730.1 - 2.4e-14 53.4 0.0 4.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN10730.1 - 5.8e-11 42.5 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN10730.1 - 1.8e-10 40.6 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN10730.1 - 1.7e-08 35.1 0.0 4.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAN10730.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 GAN10730.1 - 0.011 15.3 0.1 0.033 13.8 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 GAN10730.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 GAN10730.1 - 0.037 12.6 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 GAN10730.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 GAN10730.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GA-like PF17573.2 GAN10730.1 - 0.23 11.4 1.0 8.9 6.3 0.2 2.4 2 0 0 2 2 2 0 GA-like domain Ank_2 PF12796.7 GAN10731.1 - 4.6e-18 65.6 1.8 1e-09 38.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) TIG PF01833.24 GAN10731.1 - 1e-09 38.3 0.0 3.2e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank_4 PF13637.6 GAN10731.1 - 2.5e-08 34.3 0.1 7.7e-06 26.4 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAN10731.1 - 6e-08 32.8 1.1 0.00045 20.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAN10731.1 - 1.3e-06 28.6 0.3 0.00025 21.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN10731.1 - 0.00032 20.9 0.1 1.5 9.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat TFIIA PF03153.13 GAN10731.1 - 9.6 6.1 84.5 6.9 6.6 15.4 3.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit eIF3g PF12353.8 GAN10732.1 - 6.3e-45 152.6 5.9 1.1e-44 151.8 5.9 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 GAN10732.1 - 1.3e-18 66.6 0.1 2.9e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN10732.1 - 2e-05 24.4 0.0 5.6e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif NSP11 PF06471.12 GAN10732.1 - 0.0032 16.0 0.0 0.004 15.7 0.0 1.1 1 0 0 1 1 1 1 NSP11 zf-CCCH_7 PF18586.1 GAN10732.1 - 0.027 14.8 0.4 0.071 13.4 0.1 1.9 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_8 PF11835.8 GAN10732.1 - 0.064 13.5 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 RRM-like domain UCH PF00443.29 GAN10733.1 - 8.4e-60 202.4 3.1 1.2e-59 201.9 3.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAN10733.1 - 2.9e-30 106.0 7.7 4.2e-24 85.7 3.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 GAN10733.1 - 0.026 14.0 12.3 0.019 14.5 6.8 2.8 2 1 1 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_S11 PF00411.19 GAN10734.1 - 7.9e-47 158.2 1.3 1e-46 157.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 GAN10734.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DUF2757 PF10955.8 GAN10735.1 - 0.19 12.0 0.4 0.68 10.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) vATP-synt_E PF01991.18 GAN10735.1 - 0.21 11.0 9.4 0.016 14.7 4.6 1.5 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Phage_Gp23 PF10669.9 GAN10735.1 - 1.4 9.2 6.1 3.3 8.1 6.1 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SPRY PF00622.28 GAN10736.1 - 5.9e-22 78.0 0.5 5.9e-22 78.0 0.5 3.1 3 0 0 3 3 3 1 SPRY domain Arm PF00514.23 GAN10736.1 - 1.6e-08 34.3 0.1 0.14 12.3 0.0 6.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 GAN10736.1 - 0.00055 20.5 4.1 1.1 9.9 0.0 4.3 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 GAN10736.1 - 0.004 17.2 0.2 0.03 14.3 0.0 2.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 GAN10736.1 - 0.016 15.7 0.0 0.38 11.3 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat V-ATPase_H_C PF11698.8 GAN10736.1 - 0.018 15.1 0.4 0.13 12.3 0.1 2.5 2 0 0 2 2 2 0 V-ATPase subunit H DDRGK PF09756.9 GAN10736.1 - 9.8 5.7 8.1 2.7 7.6 0.7 2.3 2 0 0 2 2 2 0 DDRGK domain Arrestin_C PF02752.22 GAN10737.1 - 1.4e-09 38.5 2.3 3.4e-08 34.0 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN10737.1 - 3.8e-07 30.3 0.0 7.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN10737.1 - 0.0056 16.4 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like Pkinase PF00069.25 GAN10738.1 - 3e-47 161.2 0.0 4.7e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10738.1 - 1.2e-22 80.5 0.0 1.8e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN10738.1 - 0.00025 21.0 0.6 0.0006 19.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAN10738.1 - 0.0065 15.8 0.0 0.017 14.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Tropomyosin_1 PF12718.7 GAN10739.1 - 4.6e-22 78.7 28.1 1.7e-14 54.2 18.6 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 GAN10739.1 - 1.8e-10 40.6 30.5 2.1e-10 40.4 30.5 1.0 1 0 0 1 1 1 1 Tropomyosin Laminin_II PF06009.12 GAN10739.1 - 0.00011 22.3 8.0 0.00011 22.3 8.0 2.0 1 1 1 2 2 2 1 Laminin Domain II Fez1 PF06818.15 GAN10739.1 - 0.00011 22.8 18.9 0.00011 22.8 18.9 1.4 1 1 0 1 1 1 1 Fez1 Uso1_p115_C PF04871.13 GAN10739.1 - 0.0007 20.0 31.4 0.024 15.0 19.8 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 GAN10739.1 - 0.00071 19.0 26.8 0.0011 18.4 23.8 1.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EzrA PF06160.12 GAN10739.1 - 0.0019 16.5 23.2 0.0024 16.1 23.2 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA KELK PF15796.5 GAN10739.1 - 0.002 18.6 25.3 0.002 18.5 16.6 2.6 1 1 1 2 2 2 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase CLZ PF16526.5 GAN10739.1 - 0.0021 18.4 22.8 0.013 15.8 5.8 3.0 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 GAN10739.1 - 0.0049 17.2 17.5 0.027 14.8 10.6 2.4 1 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 GAN10739.1 - 0.0061 16.5 29.5 0.09 12.8 13.9 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 GAN10739.1 - 0.0062 16.6 30.7 0.017 15.2 23.1 2.0 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 GAN10739.1 - 0.0069 16.8 17.0 0.0084 16.5 17.0 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) XhlA PF10779.9 GAN10739.1 - 0.007 16.5 21.4 0.013 15.7 7.3 2.6 2 1 1 3 3 3 1 Haemolysin XhlA CENP-F_leu_zip PF10473.9 GAN10739.1 - 0.0075 16.3 30.6 0.23 11.5 13.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 GAN10739.1 - 0.0081 16.2 30.3 0.044 13.8 17.2 2.3 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain DUF724 PF05266.14 GAN10739.1 - 0.0082 16.0 14.7 0.0082 16.0 14.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF724) DUF745 PF05335.13 GAN10739.1 - 0.0084 15.8 12.4 0.0084 15.8 12.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF745) ATG16 PF08614.11 GAN10739.1 - 0.012 15.8 27.1 0.077 13.2 13.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 GAN10739.1 - 0.016 15.3 24.4 0.25 11.4 11.4 2.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 GAN10739.1 - 0.02 14.9 19.3 1.2 9.2 11.3 2.7 1 1 1 2 2 2 0 FlxA-like protein YscO PF07321.12 GAN10739.1 - 0.022 14.7 29.5 0.27 11.2 22.1 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO SlyX PF04102.12 GAN10739.1 - 0.025 15.2 20.0 0.22 12.2 4.3 2.7 2 1 1 3 3 3 0 SlyX IFT57 PF10498.9 GAN10739.1 - 0.028 13.4 16.1 0.038 13.0 16.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 GAN10739.1 - 0.031 14.3 10.4 0.18 11.9 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FPP PF05911.11 GAN10739.1 - 0.032 12.4 26.1 0.038 12.2 26.1 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil ZapB PF06005.12 GAN10739.1 - 0.034 14.6 31.1 0.98 9.9 5.3 2.7 1 1 2 3 3 3 0 Cell division protein ZapB DUF4201 PF13870.6 GAN10739.1 - 0.043 13.6 23.5 0.45 10.2 15.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 GAN10739.1 - 0.05 12.9 22.5 0.92 8.8 11.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ERM PF00769.19 GAN10739.1 - 0.05 13.4 35.7 0.06 13.2 22.9 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Prefoldin PF02996.17 GAN10739.1 - 0.058 13.3 24.2 0.87 9.5 3.2 3.1 2 1 1 3 3 3 0 Prefoldin subunit MPS2 PF17060.5 GAN10739.1 - 0.061 12.6 14.2 0.1 11.8 14.2 1.3 1 1 0 1 1 1 0 Monopolar spindle protein 2 Spc7 PF08317.11 GAN10739.1 - 0.07 12.0 26.8 0.098 11.5 26.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.12 GAN10739.1 - 0.076 11.2 22.1 0.084 11.0 22.1 1.1 1 0 0 1 1 1 0 HOOK protein DUF5082 PF16888.5 GAN10739.1 - 0.099 12.9 16.1 0.11 12.7 16.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) WXG100 PF06013.12 GAN10739.1 - 0.11 12.7 12.7 2.6 8.3 0.6 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF4407 PF14362.6 GAN10739.1 - 0.12 11.7 17.2 0.14 11.5 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 GAN10739.1 - 0.12 12.5 26.0 0.17 12.1 26.0 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 V-ATPase_C PF03223.15 GAN10739.1 - 0.15 11.4 9.6 0.11 11.8 7.0 1.9 1 1 0 1 1 1 0 V-ATPase subunit C PI3K_P85_iSH2 PF16454.5 GAN10739.1 - 0.17 11.5 21.9 1.5 8.4 21.9 2.1 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tup_N PF08581.10 GAN10739.1 - 0.19 12.1 21.9 2.5 8.4 12.4 2.1 1 1 1 2 2 2 0 Tup N-terminal Csm1_N PF18504.1 GAN10739.1 - 0.2 12.0 24.3 0.55 10.6 4.9 3.2 1 1 2 3 3 3 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 GAN10739.1 - 0.22 9.4 12.1 0.28 9.1 12.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.11 GAN10739.1 - 0.23 10.3 24.3 0.97 8.2 13.8 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SHE3 PF17078.5 GAN10739.1 - 0.29 10.8 20.1 0.63 9.7 4.1 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DivIC PF04977.15 GAN10739.1 - 0.34 10.7 25.8 0.14 11.9 2.9 3.2 1 1 2 3 3 3 0 Septum formation initiator GrpE PF01025.19 GAN10739.1 - 0.41 10.3 28.3 0.89 9.2 10.2 3.0 1 1 1 2 2 2 0 GrpE FAM76 PF16046.5 GAN10739.1 - 0.43 9.9 13.6 0.56 9.5 13.6 1.4 1 0 0 1 1 1 0 FAM76 protein FlaC_arch PF05377.11 GAN10739.1 - 0.46 10.9 15.4 4.2 7.8 0.2 3.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 GAN10739.1 - 0.47 10.6 14.0 5.2 7.2 3.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4200 PF13863.6 GAN10739.1 - 0.52 10.7 30.2 0.76 10.2 23.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DegS PF05384.11 GAN10739.1 - 0.54 9.7 18.5 1.3 8.5 3.6 2.1 1 1 1 2 2 2 0 Sensor protein DegS NPV_P10 PF05531.12 GAN10739.1 - 0.6 10.6 8.8 17 5.9 0.5 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4472 PF14739.6 GAN10739.1 - 0.64 10.8 23.8 0.98 10.2 15.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF812 PF05667.11 GAN10739.1 - 0.65 8.8 24.9 2.4 7.0 24.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 GAN10739.1 - 0.65 10.2 23.7 0.38 11.0 9.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2802 PF10975.8 GAN10739.1 - 0.67 10.1 15.6 0.88 9.7 1.4 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2802) Spc24 PF08286.11 GAN10739.1 - 0.81 10.0 24.9 0.94 9.8 5.4 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Prefoldin_3 PF13758.6 GAN10739.1 - 0.84 9.7 13.9 0.52 10.4 2.2 2.9 1 1 2 3 3 3 0 Prefoldin subunit FH2 PF02181.23 GAN10739.1 - 0.85 8.7 16.1 0.24 10.5 10.6 1.8 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF948 PF06103.11 GAN10739.1 - 0.97 9.7 10.0 26 5.2 5.5 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 GAN10739.1 - 1 9.4 24.7 1.8 8.7 17.1 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein T3SSipB PF16535.5 GAN10739.1 - 1.1 9.8 17.6 1.8 9.1 12.0 2.2 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF4795 PF16043.5 GAN10739.1 - 1.1 8.8 20.4 7.6 6.1 12.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Nup54 PF13874.6 GAN10739.1 - 1.2 9.2 19.2 2.1e+02 2.0 19.7 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Cep57_MT_bd PF06657.13 GAN10739.1 - 1.2 9.6 21.2 6.6 7.3 12.0 3.0 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Exonuc_VII_L PF02601.15 GAN10739.1 - 1.3 8.5 14.6 1.4 8.4 14.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 GAN10739.1 - 1.3 8.0 19.4 5.1 6.1 19.4 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 GAN10739.1 - 1.3 9.5 17.2 10 6.7 6.0 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 GAN10739.1 - 1.5 9.1 25.7 1.6 9.0 5.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Sec2p PF06428.11 GAN10739.1 - 1.6 8.8 25.1 17 5.5 14.4 2.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p HalX PF08663.10 GAN10739.1 - 1.6 9.1 26.9 1.4 9.3 7.7 3.5 1 1 2 3 3 3 0 HalX domain Fib_alpha PF08702.10 GAN10739.1 - 1.6 8.9 13.3 4.8 7.4 9.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 GAN10739.1 - 1.9 9.0 36.7 66 4.0 36.7 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region MRPL52 PF18699.1 GAN10739.1 - 2.1 8.6 21.5 0.2 11.9 8.3 2.8 1 1 2 3 3 3 0 Mitoribosomal protein mL52 DUF2968 PF11180.8 GAN10739.1 - 2.1 7.9 18.7 10 5.7 9.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) bZIP_2 PF07716.15 GAN10739.1 - 2.2 8.4 29.4 1.5 9.0 6.3 3.4 3 1 0 3 3 3 0 Basic region leucine zipper Prefoldin_2 PF01920.20 GAN10739.1 - 2.2 8.3 28.1 4.3 7.3 2.0 3.1 1 1 2 3 3 3 0 Prefoldin subunit Alanine_zipper PF11839.8 GAN10739.1 - 2.3 8.7 14.7 8.3 6.9 4.8 2.8 2 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein BRE1 PF08647.11 GAN10739.1 - 2.3 8.4 26.6 2.7 8.1 14.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_31 PF13614.6 GAN10739.1 - 2.8 7.8 5.3 5.2 6.9 5.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 GAN10739.1 - 2.9 6.4 21.8 3.4 6.2 8.1 1.7 1 1 0 1 1 1 0 AAA domain Striatin PF08232.12 GAN10739.1 - 3.3 8.3 19.6 12 6.5 19.6 2.0 1 1 0 1 1 1 0 Striatin family Baculo_F PF12259.8 GAN10739.1 - 3.8 5.9 8.3 4.4 5.7 7.7 1.5 1 1 0 1 1 1 0 Baculovirus F protein Golgin_A5 PF09787.9 GAN10739.1 - 3.9 6.8 23.2 5.2 6.4 23.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Med4 PF10018.9 GAN10739.1 - 4 7.1 20.8 1.4 8.5 10.8 2.5 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_1 PF00170.21 GAN10739.1 - 4.3 7.5 25.4 8.9 6.5 4.5 3.4 2 1 0 3 3 3 0 bZIP transcription factor Fmp27_WPPW PF10359.9 GAN10739.1 - 4.4 6.0 18.0 19 3.9 18.0 1.8 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-C4pol PF14260.6 GAN10739.1 - 4.6 7.8 5.1 17 6.0 0.3 2.8 1 1 2 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF3584 PF12128.8 GAN10739.1 - 4.7 4.6 23.8 3.9 4.9 20.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) BST2 PF16716.5 GAN10739.1 - 5 7.8 22.8 5.6 7.6 14.8 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4710 PF15828.5 GAN10739.1 - 5 7.3 10.3 2.5 8.3 1.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4710) FapA PF03961.13 GAN10739.1 - 5.9 5.4 21.2 2.2 6.8 13.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prominin PF05478.11 GAN10739.1 - 5.9 4.7 11.2 11 3.8 10.5 1.6 1 1 0 1 1 1 0 Prominin TolA_bind_tri PF16331.5 GAN10739.1 - 6.3 6.9 16.8 6.8 6.8 2.6 2.9 1 1 0 2 2 2 0 TolA binding protein trimerisation Fzo_mitofusin PF04799.13 GAN10739.1 - 6.4 6.3 14.9 4.2 6.9 5.7 2.2 1 1 1 2 2 2 0 fzo-like conserved region 5_nucleotid PF05761.14 GAN10739.1 - 7.2 5.4 10.9 8.9 5.1 10.9 1.3 1 0 0 1 1 1 0 5' nucleotidase family Phage_GPO PF05929.11 GAN10739.1 - 7.3 6.1 16.5 13 5.3 16.5 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Rotamase PF00639.21 GAN10739.1 - 7.6 7.6 16.7 35 5.5 8.5 3.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Nsp1_C PF05064.13 GAN10739.1 - 7.8 6.3 17.5 28 4.5 10.5 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region FemAB PF02388.16 GAN10739.1 - 7.8 5.3 19.0 0.33 9.8 11.2 1.9 1 1 1 2 2 2 0 FemAB family TMPIT PF07851.13 GAN10739.1 - 8.5 5.5 18.3 5.5 6.1 1.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein Swi5 PF07061.11 GAN10739.1 - 8.6 6.5 25.7 12 6.0 4.8 3.2 1 1 1 2 2 1 0 Swi5 Rxt3 PF08642.10 GAN10740.1 - 2.2e-26 93.1 0.1 2.2e-26 93.1 0.1 5.0 3 2 1 5 5 5 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 GAN10740.1 - 0.00015 21.8 0.0 0.0025 17.9 0.0 2.7 2 0 0 2 2 2 1 LCCL domain GHMP_kinases_N PF00288.26 GAN10740.1 - 7.8 6.8 7.1 1.2 9.4 1.6 2.5 3 0 0 3 3 3 0 GHMP kinases N terminal domain SRP-alpha_N PF04086.13 GAN10743.1 - 7.4e-52 177.1 23.0 3e-51 175.1 23.0 1.8 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 GAN10743.1 - 1.5e-49 168.3 0.1 3e-49 167.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GAN10743.1 - 3.3e-11 43.3 0.0 2.4e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 GAN10743.1 - 0.00017 20.7 0.0 0.00059 18.9 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 GAN10743.1 - 0.0036 17.0 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAN10743.1 - 0.013 15.3 0.0 0.046 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 GAN10743.1 - 0.039 14.0 0.0 0.16 12.0 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 GAN10743.1 - 0.083 12.8 0.3 2 8.3 0.1 2.9 2 1 0 2 2 2 0 NTPase Fer4_NifH PF00142.18 GAN10743.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MAJIN PF15077.6 GAN10743.1 - 1.5 8.6 5.0 3.1 7.5 5.0 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein MMR_HSR1 PF01926.23 GAN10743.1 - 2.4 8.3 8.2 0.85 9.7 1.1 3.3 2 2 0 2 2 2 0 50S ribosome-binding GTPase GET2 PF08690.10 GAN10744.1 - 9.3e-11 41.9 4.0 2.4e-07 30.7 3.9 2.3 2 0 0 2 2 2 2 GET complex subunit GET2 DUF4636 PF15468.6 GAN10744.1 - 0.13 11.9 0.4 16 5.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4636) CAML PF14963.6 GAN10744.1 - 2.6 8.1 3.7 2 8.4 0.7 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand tRNA-synt_1b PF00579.25 GAN10745.1 - 6.4e-78 262.0 0.1 1e-77 261.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 GAN10745.1 - 2.8e-05 23.7 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 GAN10745.1 - 0.013 15.3 0.1 0.35 10.7 0.1 2.4 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Borrelia_orfD PF02999.14 GAN10746.1 - 0.024 14.9 0.1 0.06 13.7 0.1 1.6 1 0 0 1 1 1 0 Borrelia orf-D family T2SSG PF08334.11 GAN10747.1 - 0.061 13.4 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G LRR_8 PF13855.6 GAN10748.1 - 4.2e-26 90.5 27.5 2.8e-09 36.6 5.8 4.4 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAN10748.1 - 2.1e-17 63.0 26.4 0.00025 21.3 5.0 5.2 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN10748.1 - 1.6e-06 27.8 22.0 2.4 9.0 0.5 8.9 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.6 GAN10748.1 - 0.0011 18.5 11.2 0.021 14.3 1.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat CSTF_C PF14304.6 GAN10748.1 - 0.29 10.8 7.5 0.45 10.2 1.4 3.8 3 1 0 3 3 3 0 Transcription termination and cleavage factor C-terminal LRR_6 PF13516.6 GAN10748.1 - 0.47 10.6 20.1 8.4 6.7 0.3 6.9 7 0 0 7 7 7 0 Leucine Rich repeat UQ_con PF00179.26 GAN10749.1 - 3.3e-46 156.4 0.0 4.1e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAN10749.1 - 0.018 14.8 0.0 0.076 12.7 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Mito_carr PF00153.27 GAN10750.1 - 7.3e-61 202.1 1.6 4.3e-19 68.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 GAN10750.1 - 0.016 15.2 0.3 8.6 6.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) Pkinase PF00069.25 GAN10751.1 - 1.3e-27 96.9 0.0 2.1e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10751.1 - 1.2e-12 47.7 0.0 2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN10751.1 - 6.1e-10 38.4 1.3 4.5e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAN10751.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN10751.1 - 0.1 12.5 0.0 0.77 9.6 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Presenilin PF01080.17 GAN10751.1 - 0.54 9.0 3.1 0.79 8.4 3.1 1.1 1 0 0 1 1 1 0 Presenilin GDP_Man_Dehyd PF16363.5 GAN10752.1 - 1.5e-60 205.4 0.0 1.8e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAN10752.1 - 1.1e-54 185.5 0.0 1.4e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN10752.1 - 1.2e-19 70.4 0.0 5e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAN10752.1 - 1.8e-16 60.2 0.0 1.3e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAN10752.1 - 1.7e-11 43.8 0.0 2.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAN10752.1 - 9e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 GAN10752.1 - 1.9e-09 37.7 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAN10752.1 - 1.4e-07 31.6 0.0 2.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GAN10752.1 - 1.9e-07 30.6 0.0 2e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 GAN10752.1 - 1.6e-05 24.6 0.0 0.00025 20.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 GAN10752.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_7 PF13241.6 GAN10752.1 - 0.07 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 GAN10752.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAN10752.1 - 0.18 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sec16_C PF12931.7 GAN10753.1 - 0.0012 18.5 0.2 0.0045 16.7 0.2 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 GAN10753.1 - 0.0025 18.6 13.7 0.82 10.6 0.5 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3318 PF11780.8 GAN10755.1 - 0.00031 20.7 0.2 0.00053 19.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3318) PP2C PF00481.21 GAN10756.1 - 1.2e-41 143.1 0.0 1.4e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C NatB_MDM20 PF09797.9 GAN10756.1 - 0.077 11.9 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4187 PF13821.6 GAN10757.1 - 4e-22 77.8 2.2 1.4e-21 76.0 2.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 GAN10757.1 - 3.8e-12 45.9 7.3 7.5e-12 45.0 7.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN10757.1 - 5.7e-06 26.3 1.8 1.8e-05 24.7 1.8 1.9 1 0 0 1 1 1 1 G-patch domain HAD_2 PF13419.6 GAN10758.1 - 1e-25 90.9 0.0 1.3e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN10758.1 - 2.4e-19 70.5 0.1 3.4e-17 63.4 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN10758.1 - 7.3e-06 26.0 0.1 1.8e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 GAN10758.1 - 0.00015 22.2 0.0 0.00026 21.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 GAN10758.1 - 0.24 11.0 0.0 0.76 9.3 0.0 1.7 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HEAT_2 PF13646.6 GAN10759.1 - 1.6e-35 121.4 2.7 7.6e-08 32.6 0.0 7.3 2 1 3 6 6 6 6 HEAT repeats HEAT PF02985.22 GAN10759.1 - 5.5e-35 116.4 23.0 0.026 14.8 0.0 13.4 13 0 0 13 13 13 8 HEAT repeat Vac14_Fab1_bd PF12755.7 GAN10759.1 - 9.7e-12 45.3 4.3 0.0083 16.7 0.0 6.7 4 3 4 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN10759.1 - 7.3e-09 35.9 9.3 0.11 12.5 0.2 5.4 4 1 1 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAN10759.1 - 2.7e-08 34.2 11.1 0.0011 19.5 0.3 6.5 6 2 2 8 8 8 3 HEAT-like repeat WD40 PF00400.32 GAN10759.1 - 1.3e-06 29.0 0.6 0.028 15.3 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat RTP1_C1 PF10363.9 GAN10759.1 - 3.5e-06 27.2 4.2 0.085 13.0 0.1 4.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 ANAPC4_WD40 PF12894.7 GAN10759.1 - 4.8e-06 26.8 0.0 0.53 10.6 0.0 4.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Adaptin_N PF01602.20 GAN10759.1 - 0.00035 19.3 11.0 0.11 11.0 0.4 4.4 2 2 1 4 4 4 2 Adaptin N terminal region Arm PF00514.23 GAN10759.1 - 0.0094 16.0 2.9 29 4.9 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cytochrom_D1 PF02239.16 GAN10759.1 - 0.11 11.1 0.0 0.24 9.9 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain API5 PF05918.11 GAN10759.1 - 0.44 9.3 3.5 0.68 8.7 0.3 2.7 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Tim17 PF02466.19 GAN10762.1 - 6.9e-09 36.1 2.9 9.4e-09 35.6 2.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Anoctamin PF04547.12 GAN10763.1 - 1.7e-112 376.5 18.0 2.2e-112 376.2 18.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel HBD PF18534.1 GAN10763.1 - 0.14 12.3 0.0 0.52 10.5 0.0 2.0 1 0 0 1 1 1 0 Helical bundle domain XH PF03469.14 GAN10763.1 - 3.9 7.4 6.1 0.29 11.0 0.6 2.0 2 0 0 2 2 2 0 XH domain DUF3899 PF13038.6 GAN10763.1 - 7.4 7.2 10.1 26 5.4 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3899) SURF4 PF02077.15 GAN10764.1 - 7.2e-87 291.4 2.8 8.1e-87 291.2 2.8 1.0 1 0 0 1 1 1 1 SURF4 family CdiI_4 PF18624.1 GAN10765.1 - 0.072 13.6 0.0 0.097 13.2 0.0 1.2 1 0 0 1 1 1 0 CDI immunity protein AA_permease PF00324.21 GAN10766.1 - 2.5e-133 445.2 41.0 3.1e-133 444.9 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN10766.1 - 5.7e-43 147.3 43.8 6.9e-43 147.1 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 GAN10766.1 - 1.7 7.3 0.0 1.7 7.3 0.0 3.5 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Porphobil_deam PF01379.20 GAN10767.1 - 1.5e-77 259.7 0.0 1.8e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 GAN10767.1 - 8.5e-18 64.5 0.1 1.7e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain RPN2_C PF18004.1 GAN10768.1 - 1e-55 188.0 8.0 2e-55 187.1 8.0 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 GAN10768.1 - 3.4e-42 140.8 23.6 1.9e-08 34.3 0.1 8.9 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAN10768.1 - 1.2e-19 70.4 0.3 1.9e-12 47.4 0.0 5.1 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.22 GAN10768.1 - 6.3e-07 29.1 0.2 6.7 7.3 0.1 6.5 6 0 0 6 6 6 1 HEAT repeat RPN1_RPN2_N PF17781.1 GAN10768.1 - 6.1e-05 22.6 1.0 6.1e-05 22.6 1.0 2.7 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain HEAT_EZ PF13513.6 GAN10768.1 - 0.0048 17.4 1.3 0.97 10.0 0.0 4.4 4 1 0 4 4 4 1 HEAT-like repeat HEAT_PBS PF03130.16 GAN10768.1 - 0.1 13.3 1.9 1.6e+02 3.4 0.0 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Vfa1 PF08432.10 GAN10768.1 - 3.8 7.8 11.8 11 6.3 7.6 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TPR_1 PF00515.28 GAN10769.1 - 1.2e-37 126.2 41.4 6.5e-06 25.7 1.2 16.1 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10769.1 - 1.1e-36 122.0 33.6 7.5e-05 22.6 1.7 16.0 16 0 0 16 16 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10769.1 - 2.6e-31 107.9 20.8 1e-07 32.4 0.1 9.6 7 3 3 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAN10769.1 - 1.7e-29 102.0 30.9 5.1e-08 33.1 0.1 10.4 6 2 5 12 12 11 9 Tetratricopeptide repeat TPR_14 PF13428.6 GAN10769.1 - 8.8e-29 97.7 9.3 0.00053 20.6 0.1 14.0 8 4 7 15 15 15 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10769.1 - 1.5e-28 96.5 37.4 6.7e-05 22.8 0.3 15.4 17 1 0 17 17 16 7 Tetratricopeptide repeat TPR_6 PF13174.6 GAN10769.1 - 6.8e-24 82.9 31.0 0.00011 22.6 0.1 13.2 13 1 0 13 13 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAN10769.1 - 2.5e-22 77.2 26.3 0.0059 16.6 0.2 12.8 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10769.1 - 4.4e-22 78.4 10.1 0.0002 22.0 0.5 9.0 7 2 3 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10769.1 - 4.2e-15 55.0 21.2 0.00018 21.7 0.1 12.1 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN10769.1 - 7.7e-11 41.5 26.1 0.056 13.1 0.1 10.3 6 4 4 10 10 10 3 TPR repeat ANAPC3 PF12895.7 GAN10769.1 - 3.3e-09 36.8 28.3 0.0009 19.4 2.0 6.0 5 2 1 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAN10769.1 - 5.5e-09 35.6 24.5 5.4e-05 22.5 1.0 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN10769.1 - 3e-06 27.3 8.6 0.96 9.6 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAN10769.1 - 9.5e-06 25.3 28.1 0.017 15.0 0.0 9.6 10 0 0 10 10 8 1 Tetratricopeptide repeat ChAPs PF09295.10 GAN10769.1 - 2.3e-05 23.6 5.5 9.2e-05 21.6 0.9 2.6 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPPII_N PF12583.8 GAN10769.1 - 0.0023 18.5 1.9 0.45 11.1 0.0 3.5 3 1 1 4 4 3 1 Tripeptidyl peptidase II N terminal Fis1_TPR_C PF14853.6 GAN10769.1 - 0.032 14.3 10.8 0.28 11.3 0.2 5.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 GAN10769.1 - 0.099 12.7 10.8 1.3 9.1 0.0 5.2 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) DUF5401 PF17380.2 GAN10769.1 - 8.6 4.3 39.1 13 3.7 39.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Methyltransf_16 PF10294.9 GAN10770.1 - 5.3e-27 94.6 0.1 4.2e-26 91.7 0.1 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAN10770.1 - 0.00019 21.3 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 GAN10770.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Stk19 PF10494.9 GAN10772.1 - 2.1e-27 96.4 0.1 3.3e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Lysine_decarbox PF03641.14 GAN10773.1 - 2.4e-37 128.0 0.0 3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 GAN10773.1 - 3.3e-18 65.8 0.0 4.2e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family Far-17a_AIG1 PF04750.14 GAN10774.1 - 5.5e-28 97.7 10.2 6.9e-28 97.3 10.2 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Aldedh PF00171.22 GAN10775.1 - 2.5e-87 293.3 0.0 2.9e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3584 PF12128.8 GAN10775.1 - 0.11 9.9 0.4 0.15 9.6 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAT PF02184.16 GAN10776.1 - 2.6e-23 81.7 64.6 8.8e-15 54.4 3.1 13.9 15 1 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 GAN10776.1 - 9.2e-20 69.7 10.6 0.0013 19.4 0.1 9.4 8 2 3 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10776.1 - 7.8e-18 64.8 0.0 0.024 15.1 0.0 6.6 4 2 3 7 7 7 5 Tetratricopeptide repeat Suf PF05843.14 GAN10776.1 - 2.7e-17 63.7 29.9 1.9e-05 24.8 0.7 7.2 3 1 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_17 PF13431.6 GAN10776.1 - 3.1e-10 39.7 0.8 0.0046 17.2 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN10776.1 - 3.4e-06 26.5 12.3 0.074 12.3 0.3 4.9 1 1 3 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAN10776.1 - 2.2e-05 24.8 9.2 0.68 10.7 0.0 8.0 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10776.1 - 0.00012 22.0 7.3 11 6.4 0.0 7.8 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10776.1 - 0.00037 20.5 3.6 26 5.3 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10776.1 - 0.00064 20.3 0.8 16 6.2 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat BSD PF03909.17 GAN10776.1 - 0.001 19.0 2.9 0.04 13.9 0.2 3.4 3 1 0 3 3 3 1 BSD domain Mad3_BUB1_I PF08311.12 GAN10776.1 - 0.0027 17.7 27.3 0.08 12.9 4.5 6.6 5 1 0 5 5 5 3 Mad3/BUB1 homology region 1 Ribosomal_S14 PF00253.21 GAN10777.1 - 2.9e-26 91.0 1.3 1.5e-25 88.7 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Spt20 PF12090.8 GAN10778.1 - 0.00031 20.4 30.9 0.00069 19.3 11.5 2.5 2 0 0 2 2 2 2 Spt20 family GREB1 PF15782.5 GAN10778.1 - 5.3 4.0 33.5 0.54 7.3 29.0 1.4 1 1 0 1 1 1 0 Gene regulated by oestrogen in breast cancer VIT1 PF01988.19 GAN10778.1 - 6.2 6.6 10.3 1.8 8.4 3.7 2.3 2 0 0 2 2 2 0 VIT family DUF702 PF05142.12 GAN10778.1 - 8.4 6.9 18.3 1.6 9.2 6.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) peroxidase PF00141.23 GAN10779.1 - 2.9e-13 50.1 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DinB PF05163.12 GAN10779.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 DinB family peroxidase PF00141.23 GAN10780.1 - 6.7e-22 78.3 0.0 1.2e-21 77.5 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Rhomboid PF01694.22 GAN10781.1 - 2.8e-07 30.6 3.4 4.4e-07 30.0 3.4 1.2 1 0 0 1 1 1 1 Rhomboid family ATP_transf PF09830.9 GAN10782.1 - 4.7e-23 81.1 0.0 7.8e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 GAN10782.1 - 8.3e-06 26.5 0.0 2.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 HIT domain DUF4922 PF16269.5 GAN10782.1 - 0.00017 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) DUF4931 PF16285.5 GAN10782.1 - 0.0052 16.1 0.2 0.022 14.0 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) HHH_4 PF14490.6 GAN10782.1 - 0.075 13.0 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain ELO PF01151.18 GAN10785.1 - 1.1e-57 195.4 30.1 1.4e-57 195.1 30.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 GAN10785.1 - 7.6 6.8 7.2 7.9 6.7 3.0 2.6 1 1 1 2 2 2 0 CCSMST1 family Kelch_6 PF13964.6 GAN10786.1 - 5.9e-25 86.7 10.2 6.7e-05 23.0 0.1 6.9 6 1 1 7 7 6 5 Kelch motif Kelch_1 PF01344.25 GAN10786.1 - 3e-21 74.7 2.4 0.00038 20.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 GAN10786.1 - 4.1e-19 68.2 6.7 0.0075 16.2 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAN10786.1 - 4e-18 64.6 1.3 0.00011 22.1 0.0 7.1 7 1 0 7 7 7 3 Kelch motif Kelch_4 PF13418.6 GAN10786.1 - 1.3e-17 63.5 20.0 2.6e-05 24.1 0.2 6.6 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN10786.1 - 8e-15 54.7 18.0 0.0012 19.1 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain YqhR PF11085.8 GAN10786.1 - 0.0021 18.0 0.2 0.0021 18.0 0.2 2.0 2 1 1 3 3 2 1 Conserved membrane protein YqhR VSP PF03302.13 GAN10786.1 - 0.015 14.2 0.6 0.029 13.2 0.6 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Phage_holin_3_6 PF07332.11 GAN10786.1 - 0.023 14.7 0.6 0.023 14.7 0.6 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5074 PF16819.5 GAN10786.1 - 0.031 14.3 0.3 0.031 14.3 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5074) ASC PF00858.24 GAN10786.1 - 0.47 9.4 8.3 0.43 9.5 0.0 3.1 1 1 2 3 3 3 0 Amiloride-sensitive sodium channel Syndecan PF01034.20 GAN10786.1 - 7.2 6.6 6.7 0.53 10.2 1.0 2.0 2 0 0 2 2 2 0 Syndecan domain SCP2 PF02036.17 GAN10788.1 - 4.1e-23 81.8 1.3 5e-23 81.5 1.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAN10788.1 - 0.0043 17.3 0.0 0.0066 16.7 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 GAN10788.1 - 0.11 12.8 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 Sterol carrier protein domain KicB PF03882.14 GAN10789.1 - 0.045 13.9 0.1 0.051 13.8 0.1 1.1 1 0 0 1 1 1 0 MukF winged-helix domain Mito_carr PF00153.27 GAN10791.1 - 1.1e-22 79.7 0.3 1.3e-09 37.9 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein TFIIA PF03153.13 GAN10791.1 - 0.17 11.8 2.0 0.25 11.3 2.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UL41A PF17591.2 GAN10792.1 - 0.19 11.8 0.9 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL41A HIG_1_N PF04588.13 GAN10793.1 - 4.8e-10 39.5 0.2 1.4e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region SEP PF08059.13 GAN10794.1 - 5.2e-27 94.2 0.0 2.4e-26 92.1 0.0 2.1 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 GAN10794.1 - 9.1e-16 57.8 0.1 1.6e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 GAN10794.1 - 4.3e-11 42.5 1.3 8.9e-10 38.2 0.3 2.4 2 0 0 2 2 2 1 UBA-like domain zf-C2H2 PF00096.26 GAN10795.1 - 2.9e-06 27.4 27.3 0.0014 19.0 4.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN10795.1 - 3.6e-05 24.0 20.9 0.0004 20.7 0.7 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN10795.1 - 0.0001 22.9 24.1 0.012 16.4 2.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger THEG4 PF15834.5 GAN10795.1 - 0.035 14.1 0.5 0.035 14.1 0.5 2.9 2 1 0 3 3 3 0 Testis highly expressed protein 4 TadF PF16964.5 GAN10795.1 - 0.16 11.7 2.1 0.26 11.0 2.1 1.4 1 0 0 1 1 1 0 Putative tight adherence pilin protein F zf-C2H2_3rep PF18868.1 GAN10795.1 - 0.54 10.9 10.0 0.45 11.2 1.5 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 GAN10795.1 - 1.2 9.5 11.4 3.7 7.9 3.2 2.7 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 GAN10795.1 - 1.8 8.4 23.6 0.043 13.6 4.7 4.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 GAN10795.1 - 2.3 8.6 11.7 5.4 7.4 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 GAN10795.1 - 2.8 7.8 6.0 0.8 9.5 1.6 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 GAN10795.1 - 3 8.2 13.0 1.1 9.6 8.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon Elf1 PF05129.13 GAN10795.1 - 3.6 7.7 10.3 4.2 7.5 1.7 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DTHCT PF08070.11 GAN10795.1 - 4.8 8.0 16.2 0.43 11.3 10.3 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region Zn_Tnp_IS1595 PF12760.7 GAN10795.1 - 7.6 6.6 8.1 22 5.1 0.6 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PMT PF02366.18 GAN10796.1 - 4.2e-77 259.0 21.1 4.2e-77 259.0 21.1 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAN10796.1 - 4.9e-60 202.5 7.2 4.9e-60 202.5 7.2 3.1 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAN10796.1 - 3.2e-08 33.6 0.6 6.8e-08 32.6 0.6 1.5 1 0 0 1 1 1 1 MIR domain DUF456 PF04306.13 GAN10796.1 - 9.9 6.5 15.5 11 6.3 7.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF456) Choline_kinase PF01633.20 GAN10797.1 - 5.1e-64 215.8 0.0 9.4e-64 214.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAN10797.1 - 6.2e-16 59.1 0.0 9.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sterol_MT_C PF08498.10 GAN10798.1 - 3.6e-27 94.5 0.5 5.9e-27 93.8 0.5 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAN10798.1 - 3.6e-19 69.2 0.0 1.3e-18 67.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN10798.1 - 2.5e-17 63.3 0.0 9.1e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GAN10798.1 - 1.1e-15 57.7 0.0 1.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 GAN10798.1 - 2.4e-14 53.4 0.0 4.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN10798.1 - 5.8e-11 42.5 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN10798.1 - 1.8e-10 40.6 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAN10798.1 - 1.7e-08 35.1 0.0 4.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAN10798.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 GAN10798.1 - 0.011 15.3 0.1 0.033 13.8 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 GAN10798.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 GAN10798.1 - 0.037 12.6 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 GAN10798.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 GAN10798.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GA-like PF17573.2 GAN10798.1 - 0.23 11.4 1.0 8.9 6.3 0.2 2.4 2 0 0 2 2 2 0 GA-like domain zf-C2H2 PF00096.26 GAN10799.1 - 0.00042 20.6 14.7 0.0076 16.7 2.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 GAN10799.1 - 0.0017 18.7 5.1 0.0018 18.6 2.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAN10799.1 - 0.0035 17.3 1.9 0.0035 17.3 1.9 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAN10799.1 - 0.0044 17.8 14.1 0.0093 16.7 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN10799.1 - 0.0088 16.3 3.8 0.0088 16.3 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding BolA PF01722.18 GAN10799.1 - 0.55 10.6 1.9 1.1 9.6 1.9 1.4 1 0 0 1 1 1 0 BolA-like protein zf-H2C2_2 PF13465.6 GAN10799.1 - 2 9.0 16.1 1.6 9.3 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain WES_acyltransf PF03007.16 GAN10800.1 - 5.3e-20 72.3 0.1 2.9e-19 69.9 0.1 1.9 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 GAN10800.1 - 6.2e-13 48.9 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 GAN10800.1 - 1.1e-05 24.3 0.1 7.7e-05 21.5 0.1 2.0 2 0 0 2 2 2 1 Condensation domain CrgA PF06781.12 GAN10800.1 - 0.13 12.4 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Cell division protein CrgA DUF1752 PF08550.10 GAN10801.1 - 1.4e-10 40.8 2.3 3.7e-10 39.5 2.3 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) NOA36 PF06524.12 GAN10801.1 - 0.00067 19.1 3.6 0.00084 18.8 3.6 1.2 1 0 0 1 1 1 1 NOA36 protein MCM_bind PF09739.9 GAN10801.1 - 0.0073 14.8 3.7 0.0093 14.5 3.7 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor RXT2_N PF08595.11 GAN10801.1 - 0.021 14.9 3.3 0.031 14.3 3.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 GAN10801.1 - 0.32 11.4 8.6 0.52 10.7 8.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAN10801.1 - 0.37 11.2 5.5 0.68 10.3 5.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 GAN10801.1 - 0.86 7.6 4.9 1 7.4 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 GAN10801.1 - 3 7.5 9.6 2.4 7.8 8.3 1.5 1 1 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 GAN10801.1 - 4.5 7.0 10.2 7.5 6.3 10.2 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Arrestin_N PF00339.29 GAN10802.1 - 4e-11 43.2 0.0 5.1e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN10802.1 - 9.1e-05 22.9 0.6 0.0025 18.3 1.2 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain TPR_1 PF00515.28 GAN10803.1 - 2e-07 30.5 1.4 0.39 10.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10803.1 - 3.9e-07 29.7 0.5 0.43 10.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10803.1 - 1.3e-05 25.0 1.1 2.5 8.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_6 PF13516.6 GAN10803.1 - 1.9e-05 24.3 0.9 0.03 14.4 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat TPR_14 PF13428.6 GAN10803.1 - 0.00055 20.5 0.1 0.86 10.6 0.3 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 GAN10803.1 - 0.00055 19.8 0.0 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like TPR_16 PF13432.6 GAN10803.1 - 0.0024 18.5 0.1 0.5 11.1 0.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN10803.1 - 0.0025 17.7 0.0 0.9 9.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_4 PF12799.7 GAN10803.1 - 0.0037 17.7 2.8 1.7 9.2 0.1 4.0 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GAN10803.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_12 PF13424.6 GAN10803.1 - 0.017 15.4 0.2 1.2 9.4 0.4 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Dak2 PF02734.17 GAN10803.1 - 0.079 12.9 0.1 0.26 11.2 0.0 1.8 2 1 0 2 2 2 0 DAK2 domain TPR_11 PF13414.6 GAN10803.1 - 0.085 12.6 0.0 11 5.7 0.0 2.7 2 1 1 3 3 3 0 TPR repeat LRR_1 PF00560.33 GAN10803.1 - 0.3 11.8 3.6 16 6.5 0.0 4.6 5 0 0 5 5 4 0 Leucine Rich Repeat TFIIA PF03153.13 GAN10804.1 - 0.051 13.6 22.2 0.082 12.9 22.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 GAN10804.1 - 0.21 11.2 15.5 0.28 10.8 15.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 GAN10804.1 - 8 4.9 18.6 12 4.3 18.6 1.3 1 1 0 1 1 1 0 Macoilin family Amidohydro_1 PF01979.20 GAN10805.1 - 2.1e-24 86.5 0.0 7.3e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAN10805.1 - 1.8e-09 37.6 0.1 9.5e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family zf-CCCH PF00642.24 GAN10806.1 - 3.5e-16 58.6 14.1 2.3e-08 33.7 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAN10806.1 - 5.5e-13 48.5 15.2 2e-07 30.8 5.9 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAN10806.1 - 3.8e-10 39.3 15.6 5.6e-05 22.8 1.6 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 GAN10806.1 - 0.0033 18.1 9.5 0.34 11.6 0.8 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 GAN10806.1 - 0.018 15.5 12.3 0.019 15.4 1.7 2.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 GAN10806.1 - 0.067 13.7 4.0 3.9 8.1 0.3 3.0 3 0 0 3 3 3 0 Oligopeptide/dipeptide transporter, C-terminal region WD40 PF00400.32 GAN10807.1 - 1.1e-39 133.7 8.3 2.3e-07 31.4 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10807.1 - 1.8e-11 44.2 0.2 1.1 9.6 0.0 5.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAN10807.1 - 2.2e-08 33.8 2.1 0.00055 19.4 0.1 3.3 2 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 GAN10807.1 - 3.2e-05 23.6 0.1 0.00034 20.3 0.1 2.2 1 1 0 1 1 1 1 PQQ-like domain DUF5046 PF16465.5 GAN10807.1 - 8.6e-05 22.1 0.3 0.58 9.6 0.1 3.2 1 1 3 4 4 4 2 Domain of unknown function (DUF5046) eIF2A PF08662.11 GAN10807.1 - 0.00064 19.7 0.0 3.5 7.5 0.0 3.4 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 GAN10807.1 - 0.0035 17.2 2.3 0.39 10.7 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat Frtz PF11768.8 GAN10807.1 - 0.031 12.6 0.0 1.1 7.5 0.0 2.6 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 GAN10807.1 - 0.13 10.9 0.7 23 3.4 0.1 3.1 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Spt20 PF12090.8 GAN10808.1 - 0.044 13.4 12.3 0.061 12.9 12.3 1.3 1 0 0 1 1 1 0 Spt20 family SIN1 PF05422.12 GAN10808.1 - 0.15 12.6 10.0 0.24 12.0 10.0 1.3 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) CRA PF06589.11 GAN10808.1 - 0.8 9.8 3.6 1.4 9.0 3.6 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Neur_chan_memb PF02932.16 GAN10808.1 - 4.8 7.2 8.4 7.7 6.5 8.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hydrolase_3 PF08282.12 GAN10808.1 - 6.9 6.3 6.0 9.2 5.9 6.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_membrane PF00664.23 GAN10809.1 - 3.2e-37 128.7 13.5 3.2e-37 128.7 13.5 2.5 2 1 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAN10809.1 - 9.7e-35 120.1 1.3 1.6e-34 119.3 0.0 2.1 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAN10809.1 - 4.6e-07 29.5 0.5 1.2e-05 24.9 0.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 GAN10809.1 - 2.6e-05 23.9 18.2 2.6e-05 23.9 18.2 2.4 2 1 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_16 PF13191.6 GAN10809.1 - 0.0047 17.3 0.1 0.012 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAN10809.1 - 0.019 14.9 1.9 0.022 14.7 0.0 2.1 2 0 0 2 2 1 0 RsgA GTPase UPF0492 PF15744.5 GAN10809.1 - 0.022 14.0 3.7 0.031 13.5 3.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 AAA_29 PF13555.6 GAN10809.1 - 0.026 14.3 1.4 0.061 13.1 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAN10809.1 - 0.029 14.7 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAN10809.1 - 0.031 14.1 0.1 0.1 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 GAN10809.1 - 0.077 13.0 0.0 0.83 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAN10809.1 - 0.11 12.7 0.0 4.6 7.5 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 GAN10809.1 - 0.14 12.2 0.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAN10809.1 - 0.21 11.1 1.2 0.9 9.1 0.5 2.2 1 1 1 2 2 2 0 AAA domain Neur_chan_memb PF02932.16 GAN10809.1 - 0.44 10.6 4.3 4.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BPL_N PF09825.9 GAN10810.1 - 4.7e-89 299.1 0.0 5.9e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 GAN10810.1 - 3.8e-22 78.6 0.0 6.6e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 GAN10810.1 - 5.4e-08 32.6 0.0 9.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Mannosyl_trans3 PF11051.8 GAN10811.1 - 1e-36 126.8 0.1 3.9e-24 85.5 0.0 2.4 1 1 1 2 2 2 2 Mannosyltransferase putative NAD_binding_4 PF07993.12 GAN10811.1 - 4e-30 104.8 0.0 3e-29 101.9 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 GAN10811.1 - 1.1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.21 GAN10811.1 - 1.1e-05 25.0 0.0 6.2e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAN10811.1 - 0.00044 19.7 0.0 0.4 10.0 0.0 2.5 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAN10811.1 - 0.033 13.3 0.6 6 5.9 0.1 3.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAN10811.1 - 0.13 11.3 1.8 3.1 6.7 0.0 2.7 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sterile PF03015.19 GAN10811.1 - 0.48 10.7 6.6 0.2 11.9 1.7 2.9 2 0 0 2 2 2 0 Male sterility protein Neugrin PF06413.11 GAN10812.1 - 1.1e-08 35.4 1.1 1.6e-08 34.8 0.3 1.5 1 1 0 1 1 1 1 Neugrin zf-CCHC PF00098.23 GAN10814.1 - 1.1e-05 25.3 4.9 0.061 13.4 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle DUF1848 PF08902.11 GAN10814.1 - 0.42 10.3 2.7 4.5 6.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) zf-CCHC_4 PF14392.6 GAN10814.1 - 4.2 7.2 6.2 3.2 7.5 0.8 2.4 1 1 1 2 2 2 0 Zinc knuckle His_kinase PF06580.13 GAN10815.1 - 0.049 14.0 6.2 1.4 9.3 0.1 4.0 2 1 1 3 3 3 0 Histidine kinase SLATT_6 PF18169.1 GAN10815.1 - 1.7 8.2 5.6 6.6 6.3 0.0 3.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 End3 PF12761.7 GAN10815.1 - 1.7 8.8 14.9 0.4 10.8 7.9 3.3 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Prp19 PF08606.11 GAN10815.1 - 3.9 7.5 12.6 4.1 7.5 0.2 4.4 4 0 0 4 4 4 0 Prp19/Pso4-like Ccdc124 PF06244.12 GAN10817.1 - 2.8e-15 57.0 32.0 2.8e-15 57.0 32.0 3.1 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HTH_WhiA PF02650.14 GAN10817.1 - 1.4 9.3 0.1 1.4 9.3 0.1 3.2 2 1 1 3 3 3 0 WhiA C-terminal HTH domain ABC_membrane PF00664.23 GAN10819.1 - 2.5e-82 276.6 39.6 1.5e-42 146.1 8.9 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAN10819.1 - 2.7e-52 176.9 0.7 7.9e-29 100.9 0.0 3.1 4 0 0 4 4 2 2 ABC transporter MTABC_N PF16185.5 GAN10819.1 - 2.1e-10 40.5 7.3 2.1e-10 40.5 7.3 2.5 2 1 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 GAN10819.1 - 3.4e-10 39.8 0.1 0.00013 21.5 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAN10819.1 - 1.8e-05 24.8 3.6 0.042 13.9 0.5 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAN10819.1 - 9.6e-05 22.1 1.0 0.076 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAN10819.1 - 0.00019 21.4 0.4 0.082 12.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAN10819.1 - 0.0024 18.3 0.3 1.1 9.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 GAN10819.1 - 0.0037 17.4 3.7 1.7 8.7 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_25 PF13481.6 GAN10819.1 - 0.018 14.6 0.1 0.44 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAN10819.1 - 0.026 13.7 0.2 2.1 7.5 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.6 GAN10819.1 - 0.026 15.0 0.5 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAN10819.1 - 0.092 13.0 0.6 29 4.9 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAN10819.1 - 0.12 12.7 3.5 5 7.4 0.3 3.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAN10819.1 - 0.21 11.3 0.2 11 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAN10819.1 - 0.3 11.1 6.1 0.29 11.2 1.0 2.5 2 0 0 2 2 2 0 Dynamin family AA_permease_2 PF13520.6 GAN10820.1 - 1.1e-66 225.5 53.5 1.3e-66 225.3 53.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAN10820.1 - 9.7e-34 116.8 43.5 1.4e-33 116.3 43.5 1.1 1 0 0 1 1 1 1 Amino acid permease PDR_assoc PF08370.11 GAN10820.1 - 0.03 14.1 1.0 8.9 6.1 0.1 3.2 2 0 0 2 2 2 0 Plant PDR ABC transporter associated ATP13 PF12921.7 GAN10820.1 - 0.046 13.6 1.0 0.068 13.0 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ATPase expression Peptidase_M56 PF05569.11 GAN10820.1 - 2.4 7.3 7.8 0.38 9.9 2.5 2.2 2 1 0 2 2 2 0 BlaR1 peptidase M56 BAG PF02179.16 GAN10821.1 - 6.6e-19 68.1 0.9 1.3e-18 67.2 0.9 1.5 1 0 0 1 1 1 1 BAG domain Ubiquitin_2 PF14560.6 GAN10821.1 - 3.4e-06 27.4 0.0 9.1e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 GAN10821.1 - 1e-05 25.2 0.1 0.00013 21.7 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin family DASH_Ask1 PF08655.10 GAN10821.1 - 0.017 15.0 0.7 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Ask1 Peripla_BP_6 PF13458.6 GAN10822.1 - 0.055 13.1 0.1 0.077 12.6 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Ribosomal_L5_C PF00673.21 GAN10823.1 - 2.5e-22 78.9 0.0 6.5e-22 77.5 0.0 1.7 1 1 1 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAN10823.1 - 1e-20 73.8 0.0 3e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 AMP-binding PF00501.28 GAN10824.1 - 2.7e-74 250.3 0.1 4e-74 249.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme CNOT11 PF10155.9 GAN10824.1 - 7.2e-30 103.7 1.1 1.5e-29 102.7 1.1 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 AMP-binding_C PF13193.6 GAN10824.1 - 6.6e-16 59.1 0.1 1.5e-15 57.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_1 PF00515.28 GAN10825.1 - 1.2e-43 145.1 26.8 2.1e-05 24.2 0.1 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10825.1 - 1.3e-42 140.5 19.4 7.9e-05 22.5 0.0 12.0 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_11 PF13414.6 GAN10825.1 - 4e-37 125.6 23.9 2.6e-07 30.2 0.4 9.5 6 3 3 9 9 9 7 TPR repeat TPR_8 PF13181.6 GAN10825.1 - 9.4e-28 94.1 27.9 0.0099 16.0 0.0 12.0 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10825.1 - 2.4e-24 83.9 12.5 0.011 16.0 0.0 9.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10825.1 - 2.7e-24 85.5 11.9 5.8e-05 23.7 0.0 8.1 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAN10825.1 - 7.2e-22 76.2 7.2 0.0091 16.7 0.0 9.7 5 3 5 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10825.1 - 1.7e-21 76.5 14.5 3.2e-07 30.8 0.3 8.2 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAN10825.1 - 2.9e-17 62.7 22.5 1.4e-05 25.3 0.8 8.6 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_9 PF13371.6 GAN10825.1 - 1.6e-13 50.6 0.1 0.00046 20.3 0.0 6.1 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAN10825.1 - 2.7e-11 43.4 0.8 0.00089 18.7 0.0 3.6 1 1 3 4 4 4 4 MalT-like TPR region TPR_7 PF13176.6 GAN10825.1 - 3.5e-09 36.0 13.2 0.0052 16.7 0.2 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN10825.1 - 6.4e-09 35.9 7.6 0.29 11.4 0.0 5.1 3 1 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 GAN10825.1 - 3.5e-08 32.8 5.2 0.0044 16.0 0.0 4.5 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 GAN10825.1 - 1.3e-07 31.1 1.2 0.69 9.1 0.3 5.1 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAN10825.1 - 1.7e-05 25.1 4.5 0.3 11.4 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAN10825.1 - 1.8e-05 24.4 19.6 0.0054 16.6 0.5 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAN10825.1 - 0.00016 22.1 19.5 1.7 9.5 0.1 9.5 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAN10825.1 - 0.0012 19.2 0.0 2.3 9.1 0.1 5.0 5 0 0 5 5 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 GAN10825.1 - 0.0032 17.5 9.0 4.8 7.3 0.0 5.4 4 3 0 4 4 4 1 Domain of Unknown Function (DUF3856) SPATA3 PF15662.5 GAN10825.1 - 0.0049 17.5 3.4 0.0081 16.8 3.4 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 3 family Sel1 PF08238.12 GAN10825.1 - 0.0094 16.6 2.3 17 6.3 0.1 4.6 5 0 0 5 5 4 0 Sel1 repeat TAF1_subA PF14929.6 GAN10825.1 - 0.014 14.8 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_21 PF09976.9 GAN10825.1 - 0.024 14.4 17.7 0.35 10.6 2.6 5.6 3 1 2 5 5 4 0 Tetratricopeptide repeat-like domain ArsR PF09824.9 GAN10825.1 - 0.042 13.4 0.0 0.28 10.7 0.0 2.4 2 1 0 2 2 2 0 ArsR transcriptional regulator SHNi-TPR PF10516.9 GAN10825.1 - 0.081 12.4 3.2 0.29 10.6 0.0 3.4 4 0 0 4 4 3 0 SHNi-TPR Mucin PF01456.17 GAN10825.1 - 0.41 10.6 24.3 0.78 9.7 24.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein BTAD PF03704.17 GAN10825.1 - 0.6 10.5 7.8 0.65 10.4 1.1 3.8 3 2 0 3 3 3 0 Bacterial transcriptional activator domain DUF5113 PF17140.4 GAN10825.1 - 0.74 9.6 9.3 0.23 11.2 0.2 3.7 5 0 0 5 5 3 0 Domain of unknown function (DUF5113) ANAPC5 PF12862.7 GAN10825.1 - 1.1 9.3 11.5 14 5.8 0.3 5.3 5 2 0 5 5 5 0 Anaphase-promoting complex subunit 5 DUF3439 PF11921.8 GAN10825.1 - 1.3 9.0 13.7 2.6 8.0 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TonB_N PF16031.5 GAN10825.1 - 8.3 6.9 9.7 20 5.7 9.7 1.5 1 0 0 1 1 1 0 TonB polyproline region SCA7 PF08313.12 GAN10826.1 - 1.8e-30 104.6 3.4 4.6e-30 103.3 3.4 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain Sgf11 PF08209.11 GAN10826.1 - 0.0036 16.8 0.1 0.0072 15.9 0.1 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Tachystatin_A PF11406.8 GAN10826.1 - 0.068 13.2 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A eIF_4EBP PF05456.11 GAN10826.1 - 4.9 7.1 12.3 2.7 8.0 1.9 2.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Roughex PF06020.11 GAN10826.1 - 9.2 5.2 11.6 8.8 5.3 2.9 2.2 2 0 0 2 2 2 0 Drosophila roughex protein E1-E2_ATPase PF00122.20 GAN10827.1 - 6.1e-26 91.0 1.9 9e-25 87.2 0.1 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAN10827.1 - 8.3e-07 29.5 0.2 0.015 15.6 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN10827.1 - 0.00083 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAN10827.1 - 0.0052 16.8 0.6 0.55 10.3 0.0 3.0 3 0 0 3 3 3 1 Cation transport ATPase (P-type) DUF508 PF04370.12 GAN10827.1 - 0.025 14.3 0.0 0.08 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF508) CytochromB561_N PF09786.9 GAN10827.1 - 0.032 13.2 0.3 0.064 12.3 0.3 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ribosomal_S19e PF01090.19 GAN10828.1 - 4.1e-60 201.4 0.1 4.6e-60 201.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 GAN10828.1 - 0.11 12.7 0.3 0.23 11.6 0.1 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain WD40 PF00400.32 GAN10829.1 - 1.9e-44 148.7 14.9 7.6e-06 26.6 0.2 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10829.1 - 2e-26 92.1 1.2 0.00012 22.3 0.0 8.4 4 2 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN10829.1 - 8.8e-11 42.0 2.0 0.0052 16.7 0.1 4.2 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 GAN10829.1 - 2.2e-07 30.7 3.5 0.0032 17.1 2.0 3.5 2 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 GAN10829.1 - 2e-06 28.1 1.6 1.4 9.5 0.0 5.5 6 0 0 6 6 6 2 PQQ-like domain WD40_like PF17005.5 GAN10829.1 - 3.5e-06 26.6 2.7 1.4 8.2 0.0 4.7 2 2 2 4 4 4 3 WD40-like domain RAB3GAP2_N PF14655.6 GAN10829.1 - 0.00085 18.7 0.0 3.3 6.9 0.0 3.3 3 0 0 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Lactonase PF10282.9 GAN10829.1 - 0.0018 17.6 0.4 0.12 11.6 0.0 3.3 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller IKI3 PF04762.12 GAN10829.1 - 0.0048 15.0 0.0 2.1 6.2 0.0 3.2 4 0 0 4 4 4 1 IKI3 family Cytochrom_D1 PF02239.16 GAN10829.1 - 0.0049 15.5 0.1 0.68 8.4 0.0 2.8 3 0 0 3 3 3 2 Cytochrome D1 heme domain PQQ PF01011.21 GAN10829.1 - 0.0071 16.2 5.6 10 6.3 0.2 5.0 4 0 0 4 4 4 1 PQQ enzyme repeat Frtz PF11768.8 GAN10829.1 - 0.041 12.2 0.0 2.1 6.5 0.0 2.9 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 GAN10830.1 - 4.3e-37 127.9 0.0 1.1e-36 126.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10830.1 - 4.5e-20 72.0 0.0 9.2e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN10830.1 - 6.4e-08 32.2 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RVT_1 PF00078.27 GAN10831.1 - 1.9e-06 27.6 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GAGE PF05831.11 GAN10832.1 - 0.19 12.3 4.2 0.22 12.1 1.5 2.3 1 1 1 2 2 2 0 GAGE protein TPR_1 PF00515.28 GAN10833.1 - 1.7e-18 65.6 11.0 3.4e-07 29.8 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAN10833.1 - 8.2e-17 60.5 12.8 0.0074 17.0 0.5 7.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10833.1 - 9.1e-17 59.8 16.6 1.3e-06 28.1 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10833.1 - 1.3e-16 59.3 5.7 4.4e-06 26.5 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10833.1 - 2e-14 53.8 22.5 1.9e-05 25.0 1.0 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10833.1 - 7.8e-14 51.0 6.3 0.88 10.1 0.0 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10833.1 - 1.6e-12 47.8 10.9 0.0001 22.9 0.3 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN10833.1 - 1e-09 38.5 8.9 0.16 12.2 0.1 5.7 6 0 0 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAN10833.1 - 1.7e-06 27.6 15.9 9.1e-05 22.1 0.2 7.0 7 1 1 8 8 8 1 TPR repeat TPR_12 PF13424.6 GAN10833.1 - 3.6e-06 27.2 15.7 0.00027 21.2 0.4 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAN10833.1 - 4.6e-06 26.3 7.7 0.18 11.9 0.0 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN10833.1 - 8.8e-06 26.0 12.7 1.6 9.5 0.1 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAN10833.1 - 1.4e-05 25.2 6.8 2.4 8.4 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAN10833.1 - 1.4e-05 25.2 8.2 1 10.2 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC8 PF04049.13 GAN10833.1 - 0.00022 21.3 0.0 0.0006 19.9 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_MalT PF17874.1 GAN10833.1 - 0.00085 18.8 30.2 0.0018 17.8 1.6 5.8 6 1 2 8 8 7 4 MalT-like TPR region TPR_21 PF09976.9 GAN10833.1 - 0.00094 18.9 2.3 0.0099 15.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain NARP1 PF12569.8 GAN10833.1 - 0.0083 15.1 0.1 0.29 10.0 0.0 2.3 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 DUF438 PF04282.13 GAN10833.1 - 0.014 15.3 0.3 0.077 13.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF438) TPR_15 PF13429.6 GAN10833.1 - 0.016 14.5 6.7 0.038 13.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3682 PF12446.8 GAN10833.1 - 0.035 14.6 7.9 0.082 13.4 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Coatomer_WDAD PF04053.14 GAN10833.1 - 0.049 12.7 0.7 0.11 11.5 0.7 1.6 1 0 0 1 1 1 0 Coatomer WD associated region TPR_20 PF14561.6 GAN10833.1 - 0.1 13.0 6.5 0.32 11.4 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4398 PF14346.6 GAN10833.1 - 4.7 7.9 6.5 0.63 10.7 0.1 3.0 3 0 0 3 3 1 0 Domain of unknown function (DUF4398) Sld5 PF05916.11 GAN10834.1 - 7.5e-21 74.6 1.7 1.8e-20 73.4 1.7 1.6 1 1 0 1 1 1 1 GINS complex protein Glyco_transf_5 PF08323.11 GAN10835.1 - 4.4e-14 52.8 0.0 1.8e-13 50.8 0.0 2.1 2 1 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GAN10835.1 - 8.3e-14 51.5 0.0 2.3e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAN10835.1 - 1e-10 42.2 0.0 2.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN10835.1 - 0.0036 17.3 0.0 0.4 10.7 0.0 3.1 3 1 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAN10835.1 - 0.0072 16.8 0.0 0.038 14.4 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Metallophos PF00149.28 GAN10836.1 - 3.9e-37 128.7 0.1 9.2e-37 127.5 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transglut_core PF01841.19 GAN10837.1 - 1.5e-06 28.6 0.0 3.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Spt20 PF12090.8 GAN10837.1 - 0.00017 21.3 8.2 0.00017 21.3 8.2 2.1 2 0 0 2 2 2 1 Spt20 family SUIM_assoc PF16619.5 GAN10837.1 - 0.79 9.8 13.7 2.4 8.3 13.7 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 GAN10838.1 - 4.7e-46 157.3 25.8 4.7e-46 157.3 25.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 GAN10838.1 - 1.9e-06 26.5 0.2 1.9e-06 26.5 0.2 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Syndecan PF01034.20 GAN10839.1 - 0.024 14.6 0.6 0.052 13.5 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 GAN10840.1 - 3.5e-71 239.7 0.0 6.4e-71 238.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10840.1 - 4.8e-47 160.4 0.0 8.9e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 GAN10840.1 - 1.1e-27 96.3 0.0 2.4e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 GAN10840.1 - 1.6e-09 38.1 0.0 3.5e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 GAN10840.1 - 9.1e-09 35.8 0.0 2.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 GAN10840.1 - 1.2e-08 35.0 0.0 2.7e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 GAN10840.1 - 2.6e-08 33.5 0.0 4.2e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SAM_PNT PF02198.16 GAN10840.1 - 0.034 14.1 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain US30 PF17624.2 GAN10840.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function Sec1 PF00995.23 GAN10841.1 - 4.4e-130 435.6 1.9 5e-130 435.4 1.9 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.19 GAN10841.1 - 0.061 13.4 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain Glyco_transf_49 PF13896.6 GAN10842.1 - 7.9e-60 202.9 2.0 5.2e-48 164.1 1.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 GAN10842.1 - 0.12 12.9 0.6 0.29 11.7 0.6 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ribosomal_S8 PF00410.19 GAN10843.1 - 4.2e-22 78.5 0.1 2.5e-21 76.0 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 LSM PF01423.22 GAN10844.1 - 2e-18 65.8 0.4 2.5e-18 65.5 0.4 1.1 1 0 0 1 1 1 1 LSM domain Glucan_synthase PF02364.15 GAN10845.1 - 0 1272.3 0.7 0 1271.1 0.0 1.8 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GAN10845.1 - 1.1e-37 129.3 0.5 3.2e-37 127.8 0.5 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_18 PF00704.28 GAN10846.1 - 9.6e-17 61.7 0.0 1.3e-11 44.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Acetyltransf_1 PF00583.25 GAN10847.1 - 2.8e-05 24.3 0.2 0.00071 19.8 0.1 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN10847.1 - 0.00086 19.7 0.0 0.73 10.3 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain zf-MYND PF01753.18 GAN10848.1 - 3.5e-05 23.8 9.7 3.5e-05 23.8 9.7 2.3 2 0 0 2 2 2 1 MYND finger TPR_8 PF13181.6 GAN10848.1 - 0.0016 18.5 0.1 0.12 12.6 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAN10848.1 - 0.004 16.9 0.1 0.035 13.9 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10848.1 - 0.0081 16.2 0.0 0.057 13.5 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Aminotran_5 PF00266.19 GAN10849.1 - 8.8e-28 97.3 0.0 1.2e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 GAN10849.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain RRM_1 PF00076.22 GAN10850.1 - 7.4e-28 96.2 0.0 7.5e-15 54.5 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAN10850.1 - 0.00034 20.7 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 GAN10850.1 - 0.0004 20.2 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_9 PF18444.1 GAN10850.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF1866 PF08952.11 GAN10850.1 - 0.064 13.1 0.0 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF4290 PF14123.6 GAN10850.1 - 0.098 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) F-box-like PF12937.7 GAN10851.1 - 3e-07 30.2 0.2 8.9e-07 28.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN10851.1 - 5.6e-06 26.1 0.1 1.7e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GAN10851.1 - 0.23 11.9 14.8 0.22 12.0 0.3 6.2 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) TPT PF03151.16 GAN10852.1 - 3e-47 161.4 20.8 3.8e-47 161.0 20.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAN10852.1 - 9.8e-14 51.3 21.4 1.4e-13 50.7 21.4 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAN10852.1 - 4.4e-10 39.9 30.5 1.5e-05 25.2 11.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Pkinase PF00069.25 GAN10853.1 - 2.4e-15 56.6 0.0 5.2e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 GAN10854.1 - 0.0021 18.9 1.1 0.0078 17.1 1.1 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 GAN10854.1 - 0.075 13.3 0.2 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Herpes_gE PF02480.16 GAN10854.1 - 0.078 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2269 PF10027.9 GAN10854.1 - 0.1 12.7 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF5129 PF17173.4 GAN10854.1 - 0.12 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) LapA_dom PF06305.11 GAN10854.1 - 0.7 9.8 5.6 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SPX PF03105.19 GAN10855.1 - 4.5e-48 165.1 16.4 7.5e-48 164.4 16.4 1.4 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 GAN10855.1 - 3.5e-07 30.2 8.3 6.4e-07 29.4 8.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAN10855.1 - 1.5e-06 27.9 9.6 3.1e-06 26.9 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN10855.1 - 3.6e-06 26.7 8.6 6e-06 26.0 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN10855.1 - 4.4e-06 26.5 8.9 8.4e-06 25.6 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAN10855.1 - 6.5e-06 26.0 9.1 1.9e-05 24.5 9.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAN10855.1 - 6.7e-06 26.3 9.1 1.2e-05 25.5 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAN10855.1 - 8.6e-06 25.7 5.2 2e-05 24.5 5.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAN10855.1 - 0.00019 21.2 8.9 0.00044 20.0 9.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 PSCyt2 PF07583.11 GAN10855.1 - 0.0064 16.5 0.4 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1549) zf-rbx1 PF12678.7 GAN10855.1 - 0.0086 16.3 5.2 0.025 14.8 5.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GAN10855.1 - 0.021 14.6 3.7 0.021 14.6 3.7 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 GAN10855.1 - 0.085 13.0 4.5 0.21 11.8 4.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF4092 PF13322.6 GAN10855.1 - 0.17 11.8 0.1 23 4.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4092) zf-RING_6 PF14835.6 GAN10855.1 - 1.1 9.2 5.5 4.9 7.1 5.5 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF3716 PF12511.8 GAN10856.1 - 0.055 13.5 1.0 0.11 12.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) TTC5_OB PF16669.5 GAN10857.1 - 0.16 11.7 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain Aa_trans PF01490.18 GAN10858.1 - 5.1e-64 216.5 30.3 5.7e-64 216.3 30.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 GAN10858.1 - 2.9e-06 26.4 40.4 7.2e-06 25.1 40.4 1.6 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 GAN10858.1 - 0.065 12.0 28.8 0.025 13.4 24.0 2.5 1 1 1 2 2 2 0 Spore germination protein CENP-K PF11802.8 GAN10859.1 - 0.001 18.7 10.9 0.0045 16.6 10.9 1.8 1 1 0 1 1 1 1 Centromere-associated protein K TAFII55_N PF04658.13 GAN10860.1 - 7.4e-52 175.3 0.2 7.4e-52 175.3 0.2 2.3 2 1 0 2 2 2 1 TAFII55 protein conserved region BUD22 PF09073.10 GAN10860.1 - 0.0014 18.1 25.4 0.0014 18.1 25.4 2.3 1 1 2 3 3 3 1 BUD22 Atg14 PF10186.9 GAN10860.1 - 0.77 8.8 4.7 1.3 8.0 4.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SURF2 PF05477.11 GAN10860.1 - 0.91 9.2 21.7 0.074 12.7 16.5 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Arc_PepC_II PF06847.11 GAN10860.1 - 2.4 8.7 3.9 0.76 10.3 0.1 2.1 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II CDC45 PF02724.14 GAN10860.1 - 3.5 5.8 26.1 5.7 5.1 26.1 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GAN10860.1 - 7.6 5.9 39.3 0.7 9.3 33.8 1.9 2 0 0 2 2 2 0 SDA1 Sbi-IV PF11621.8 GAN10861.1 - 0.024 15.0 1.4 0.41 11.0 0.0 2.8 2 1 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Transposase_21 PF02992.14 GAN10862.1 - 8.3e-10 38.3 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF3435 PF11917.8 GAN10862.1 - 0.065 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF1258 PF06869.12 GAN10862.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Sugar_tr PF00083.24 GAN10863.1 - 4.1e-130 434.7 29.4 5.9e-130 434.1 29.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN10863.1 - 2.8e-36 125.2 56.3 5.1e-30 104.6 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAN10863.1 - 0.0042 15.4 1.4 0.0042 15.4 1.4 2.5 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Adenylsucc_synt PF00709.21 GAN10864.1 - 1.8e-180 600.4 0.0 2e-180 600.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase RIBIOP_C PF04950.12 GAN10865.1 - 2.1e-93 312.9 0.1 2.1e-93 312.9 0.1 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAN10865.1 - 2.6e-31 107.5 0.0 1.5e-30 105.1 0.0 2.5 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 GAN10865.1 - 2.9e-06 26.9 0.0 0.0011 18.5 0.0 2.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAN10865.1 - 3.1e-06 27.5 0.0 9.9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN10865.1 - 9.7e-05 22.8 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAN10865.1 - 0.00011 22.6 0.0 0.0003 21.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAN10865.1 - 0.00013 22.1 0.0 0.0005 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAN10865.1 - 0.00035 20.6 0.2 0.0054 16.8 0.1 2.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAN10865.1 - 0.0018 18.0 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 GAN10865.1 - 0.0033 17.2 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAN10865.1 - 0.004 17.5 0.0 0.016 15.6 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.6 GAN10865.1 - 0.0041 17.7 0.0 0.0041 17.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 GAN10865.1 - 0.0071 16.9 0.0 0.0071 16.9 0.0 3.2 4 0 0 4 4 3 1 ABC transporter AAA_28 PF13521.6 GAN10865.1 - 0.0077 16.5 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 GAN10865.1 - 0.016 15.1 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 GAN10865.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAN10865.1 - 0.022 14.8 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 GAN10865.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 GAN10865.1 - 0.056 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 GAN10865.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 GAN10865.1 - 0.084 12.8 0.1 0.45 10.4 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase AAA_11 PF13086.6 GAN10865.1 - 0.098 12.4 0.1 0.098 12.4 0.1 3.9 3 1 1 4 4 3 0 AAA domain AAA_7 PF12775.7 GAN10865.1 - 0.11 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 GAN10865.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase CK_II_beta PF01214.18 GAN10866.1 - 4.4e-73 245.0 0.2 1.6e-72 243.1 0.2 1.9 1 1 0 1 1 1 1 Casein kinase II regulatory subunit CDC45 PF02724.14 GAN10866.1 - 1.2 7.3 5.3 1.4 7.2 0.2 2.0 2 0 0 2 2 2 0 CDC45-like protein PTPRCAP PF15713.5 GAN10866.1 - 4 7.7 12.7 1.8 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Spt5_N PF11942.8 GAN10866.1 - 6.3 7.8 20.9 1.4 9.9 5.5 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal HSP70 PF00012.20 GAN10867.1 - 3.1e-260 864.5 8.1 3.5e-260 864.3 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN10867.1 - 5.1e-16 58.4 0.1 1.3e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAN10867.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 GAN10867.1 - 0.028 13.7 0.2 0.071 12.4 0.2 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF3849 PF12960.7 GAN10867.1 - 0.21 11.6 2.6 0.19 11.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) MutS_III PF05192.18 GAN10867.1 - 1.7 8.8 4.3 22 5.2 0.8 2.4 2 1 0 2 2 2 0 MutS domain III SWI-SNF_Ssr4 PF08549.10 GAN10867.1 - 2 7.0 6.2 6.6 5.2 0.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) PrmA PF06325.13 GAN10869.1 - 2.3e-13 50.2 0.1 3.3e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAN10869.1 - 9.4e-12 44.8 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 GAN10869.1 - 1.2e-06 28.4 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 GAN10869.1 - 4.7e-06 27.2 0.0 1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAN10869.1 - 1.5e-05 24.8 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 GAN10869.1 - 2e-05 24.4 0.1 2.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 GAN10869.1 - 0.00076 18.8 0.3 0.0015 17.8 0.2 1.3 1 1 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_15 PF09445.10 GAN10869.1 - 0.004 16.7 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 GAN10869.1 - 0.012 16.3 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAN10869.1 - 0.014 16.0 0.0 0.03 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAN10869.1 - 0.044 13.6 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 GAN10869.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase HAUS6_N PF14661.6 GAN10870.1 - 2.3e-13 50.2 0.3 3.4e-13 49.7 0.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus zf-CCCH_2 PF14608.6 GAN10871.1 - 1.1e-10 41.6 28.2 6.2e-05 23.3 5.9 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger XPG_I PF00867.18 GAN10871.1 - 0.14 12.6 0.9 1 9.7 0.9 2.6 1 0 0 1 1 1 0 XPG I-region CLN3 PF02487.17 GAN10871.1 - 0.44 9.5 3.2 0.41 9.6 0.1 2.1 2 0 0 2 2 2 0 CLN3 protein Ras PF00071.22 GAN10872.1 - 3.4e-52 176.3 0.0 6.3e-52 175.4 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN10872.1 - 8.6e-35 119.6 2.5 8.6e-35 119.6 0.2 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN10872.1 - 2.5e-12 46.6 0.1 3.5e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAN10872.1 - 4e-06 26.9 1.2 7.4e-06 26.0 0.1 2.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAN10872.1 - 0.00022 21.5 0.0 0.0024 18.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 GAN10872.1 - 0.0054 16.2 0.7 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAN10872.1 - 0.0054 16.3 0.1 0.022 14.3 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAN10872.1 - 0.0069 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAN10872.1 - 0.014 15.3 0.0 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase FAD-SLDH PF12318.8 GAN10872.1 - 0.029 14.4 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase TniB PF05621.11 GAN10872.1 - 0.03 13.7 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 GAN10872.1 - 0.053 13.9 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_32 PF13654.6 GAN10872.1 - 0.061 12.1 0.0 0.16 10.7 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 GAN10872.1 - 0.063 13.0 0.0 0.063 13.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAN10872.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 GAN10872.1 - 0.069 13.2 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAN10872.1 - 0.08 13.5 0.1 0.26 11.8 0.0 1.9 2 1 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 GAN10872.1 - 0.11 12.0 2.3 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 GAN10872.1 - 0.13 11.8 0.1 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Nucleoside_tran PF01733.18 GAN10873.1 - 3.7e-22 79.1 8.3 4.4e-22 78.9 5.2 2.1 1 1 1 2 2 2 2 Nucleoside transporter Mfa1 PF17445.2 GAN10873.1 - 0.27 11.3 0.9 0.55 10.3 0.1 1.9 2 0 0 2 2 2 0 Mating factor A1 Gpr1_Fun34_YaaH PF01184.19 GAN10874.1 - 4.9e-33 114.5 23.3 5.8e-33 114.2 23.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ABC2_membrane PF01061.24 GAN10875.1 - 1e-86 289.7 63.3 1.4e-47 161.8 18.1 3.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAN10875.1 - 2.7e-37 128.3 0.1 7.4e-21 75.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAN10875.1 - 1.8e-35 120.7 5.7 6.3e-27 93.3 0.1 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAN10875.1 - 1.1e-14 54.7 0.2 2.4e-14 53.7 0.2 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAN10875.1 - 3e-14 52.9 29.1 1.7e-08 34.0 10.5 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 GAN10875.1 - 6.2e-07 30.0 0.0 0.0027 18.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAN10875.1 - 4.5e-06 26.3 1.1 0.016 15.0 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAN10875.1 - 1.5e-05 25.0 0.1 0.064 13.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAN10875.1 - 5.6e-05 23.1 1.5 0.0015 18.5 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 GAN10875.1 - 0.00014 22.4 0.1 0.23 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAN10875.1 - 0.00024 21.3 0.2 0.058 13.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAN10875.1 - 0.00081 19.7 0.1 0.23 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAN10875.1 - 0.022 14.5 1.7 2.3 7.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAN10875.1 - 0.029 14.9 4.8 0.39 11.2 0.1 3.4 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 GAN10875.1 - 0.032 13.8 1.1 0.17 11.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAN10875.1 - 0.033 13.8 1.0 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 GAN10875.1 - 0.085 13.1 1.3 0.76 10.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAN10875.1 - 0.11 12.4 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ABC2_membrane_2 PF12679.7 GAN10875.1 - 0.12 11.6 13.4 0.85 8.8 0.5 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein NACHT PF05729.12 GAN10875.1 - 0.15 12.0 0.8 6.7 6.6 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 GAN10875.1 - 0.15 11.3 0.1 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Isochorismatase PF00857.20 GAN10875.1 - 0.18 12.0 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Isochorismatase family MMR_HSR1 PF01926.23 GAN10875.1 - 0.26 11.4 1.5 12 6.0 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF5542 PF17696.1 GAN10875.1 - 8.4 6.6 7.0 32 4.7 4.4 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5542) RhoGAP PF00620.27 GAN10876.1 - 9.1e-13 48.3 1.0 2.9e-12 46.7 0.0 2.3 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 GAN10876.1 - 7.1e-12 45.4 0.4 8.6e-11 42.0 0.1 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 GAN10876.1 - 9.7e-08 32.0 0.0 2.4e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BAR PF03114.18 GAN10876.1 - 0.00018 21.2 1.6 0.00018 21.2 1.6 3.3 3 1 1 4 4 4 1 BAR domain DUF2683 PF10884.8 GAN10876.1 - 0.042 14.1 0.4 0.19 12.0 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) PIN_8 PF18476.1 GAN10876.1 - 0.46 10.3 5.3 0.46 10.3 0.9 2.5 2 0 0 2 2 2 0 PIN like domain SRP-alpha_N PF04086.13 GAN10876.1 - 2.2 8.1 16.5 0.056 13.4 2.5 2.6 3 0 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal Exo_endo_phos PF03372.23 GAN10877.1 - 6.8e-07 29.0 0.0 1.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAN10877.1 - 0.095 12.6 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Abhydro_lipase PF04083.16 GAN10878.1 - 3.6e-19 68.1 0.0 8.8e-19 66.8 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAN10878.1 - 2e-06 27.6 0.3 3.9e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAN10878.1 - 1.2e-05 24.8 0.0 0.00087 18.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAN10878.1 - 0.00076 20.1 0.2 0.0011 19.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_1 PF00583.25 GAN10879.1 - 1.9e-11 44.2 0.1 2.3e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN10879.1 - 9.5e-09 35.6 0.1 1.4e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAN10879.1 - 3.3e-08 33.5 0.1 4.4e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40_4 PF16300.5 GAN10880.1 - 2.3e-14 53.0 0.1 4.3e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 GAN10880.1 - 3e-11 43.0 0.0 6.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 GAN10880.1 - 8.7e-07 29.5 0.5 0.29 12.1 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10880.1 - 1.3e-06 28.6 0.0 0.00025 21.3 0.0 3.2 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN10880.1 - 0.00086 19.2 0.0 0.0037 17.2 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 GAN10880.1 - 0.041 13.1 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Nup160 PF11715.8 GAN10880.1 - 0.16 10.6 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN10880.1 - 0.17 10.8 0.0 0.52 9.2 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sec63 PF02889.16 GAN10881.1 - 1.5e-26 93.2 0.1 3.4e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 GAN10881.1 - 5.3e-24 84.9 0.0 1.2e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAN10881.1 - 1.9e-14 54.1 0.1 5.8e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAN10881.1 - 1.7e-09 38.0 0.5 2.2e-08 34.4 0.2 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 GAN10881.1 - 5.2e-05 23.6 0.8 0.00071 19.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAN10881.1 - 0.00012 21.3 0.0 0.00041 19.5 0.0 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 GAN10881.1 - 0.00071 19.9 0.0 0.0029 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 GAN10881.1 - 0.0036 16.9 1.6 0.013 15.0 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 GAN10881.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 GAN10881.1 - 0.029 14.2 0.0 0.13 12.1 0.0 2.2 1 0 0 1 1 1 0 Helicase SWI2_SNF2 PF18766.1 GAN10881.1 - 0.093 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase CBM_21 PF03370.13 GAN10882.1 - 2.8e-25 88.7 2.3 2.8e-25 88.7 2.3 1.8 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAN10882.1 - 7.5e-14 52.1 1.9 2e-13 50.7 1.9 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Exo_endo_phos PF03372.23 GAN10883.1 - 5.4e-06 26.1 0.1 1e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YlmH_RBD PF17774.1 GAN10884.1 - 0.069 13.5 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH HSP90 PF00183.18 GAN10885.1 - 6.1e-105 352.1 1.5 8.9e-101 338.3 0.1 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 GAN10885.1 - 1.8e-11 44.0 0.2 4.5e-11 42.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAN10885.1 - 3.2e-07 30.8 0.2 2e-06 28.3 0.2 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5491 PF17595.2 GAN10885.1 - 0.019 15.3 0.1 0.06 13.7 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5491) Ammonium_transp PF00909.21 GAN10886.1 - 1e-105 353.7 25.1 4.9e-105 351.5 25.1 1.8 1 1 0 1 1 1 1 Ammonium Transporter Family MCM_bind PF09739.9 GAN10887.1 - 8.6e-112 374.5 9.9 7.4e-89 298.8 5.3 2.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 GAN10887.1 - 0.12 12.8 0.1 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 MCM AAA-lid domain Thymosin PF01290.20 GAN10887.1 - 7.2 6.4 6.1 0.5 10.1 0.5 2.0 2 0 0 2 2 2 0 Thymosin beta-4 family DUF3027 PF11228.8 GAN10888.1 - 0.052 13.6 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) YebO PF13974.6 GAN10888.1 - 3.9 7.6 6.6 4.7 7.4 0.2 2.6 2 0 0 2 2 2 0 YebO-like protein HutD PF05962.11 GAN10889.1 - 3.5e-24 85.8 0.0 7.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 HutD AstE_AspA PF04952.14 GAN10889.1 - 2.2e-13 49.9 0.3 1e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family Lactamase_B_2 PF12706.7 GAN10890.1 - 6e-38 130.4 0.0 1.1e-36 126.2 0.0 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAN10890.1 - 2.1e-15 57.0 0.0 2.1e-14 53.7 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAN10890.1 - 0.0046 17.0 2.0 0.21 11.5 1.4 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Na_Ca_ex PF01699.24 GAN10891.1 - 1.9e-46 157.8 49.2 1e-25 90.5 16.7 2.9 2 1 1 3 3 3 2 Sodium/calcium exchanger protein MLANA PF14991.6 GAN10891.1 - 0.046 14.0 0.7 0.59 10.4 0.0 2.6 2 0 0 2 2 2 0 Protein melan-A Chordopox_A13L PF05961.11 GAN10892.1 - 0.66 10.3 2.6 2.4 8.5 0.0 3.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein MAS20 PF02064.15 GAN10893.1 - 2.6e-42 144.0 0.3 3.8e-42 143.4 0.3 1.2 1 0 0 1 1 1 1 MAS20 protein import receptor IncFII_repA PF02387.15 GAN10893.1 - 0.067 12.4 2.3 0.089 12.0 2.3 1.1 1 0 0 1 1 1 0 IncFII RepA protein family MRF_C1 PF13887.6 GAN10893.1 - 0.12 11.6 0.1 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Calcipressin PF04847.12 GAN10894.1 - 1.3e-30 106.6 0.7 2.4e-30 105.7 0.7 1.5 1 1 0 1 1 1 1 Calcipressin HMG-CoA_red PF00368.18 GAN10895.1 - 3.1e-144 480.5 4.0 4.6e-144 479.9 4.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 GAN10895.1 - 2.7e-11 43.6 7.6 1.1e-10 41.6 7.6 2.0 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation PLDc PF00614.22 GAN10896.1 - 1.8e-16 59.5 1.7 2.8e-08 33.6 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAN10896.1 - 2.5e-16 59.7 2.2 7.2e-11 42.1 1.8 3.4 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 GAN10896.1 - 5.2e-10 39.3 1.0 1.9e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 PX domain PH PF00169.29 GAN10896.1 - 3e-06 27.7 0.9 1.2e-05 25.8 0.9 2.1 1 0 0 1 1 1 1 PH domain Pap_E4 PF02711.14 GAN10896.1 - 0.051 14.5 4.8 0.24 12.4 4.8 2.1 1 0 0 1 1 1 0 E4 protein ASPRs PF17641.2 GAN10896.1 - 0.13 12.6 0.3 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Ancylostoma-associated secreted protein related CAP_N PF01213.19 GAN10896.1 - 2.2 7.7 9.7 4.4 6.7 9.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GAN10896.1 - 9.1 6.3 12.6 25 4.9 12.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PA_decarbox PF05870.11 GAN10898.1 - 2e-17 63.3 0.6 2.2e-17 63.1 0.6 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF_C PF17409.2 GAN10898.1 - 5.8e-09 35.6 0.7 8.1e-09 35.1 0.6 1.3 1 1 0 1 1 1 1 MoaF C-terminal domain Glycolytic PF00274.19 GAN10898.1 - 0.0015 17.3 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Prefoldin PF02996.17 GAN10899.1 - 4e-33 113.9 2.7 4e-33 113.9 2.7 1.4 2 0 0 2 2 2 1 Prefoldin subunit YqhG PF11079.8 GAN10899.1 - 0.041 12.8 0.4 0.19 10.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial protein YqhG of unknown function AAA_assoc_C PF09821.9 GAN10899.1 - 0.15 12.6 1.9 2.4 8.7 0.3 2.6 2 1 0 2 2 2 0 C-terminal AAA-associated domain Prefoldin_2 PF01920.20 GAN10899.1 - 0.2 11.6 5.5 2.3 8.2 0.1 2.4 2 1 0 2 2 2 0 Prefoldin subunit MMgT PF10270.9 GAN10900.1 - 1.5e-15 57.4 0.2 1.9e-15 57.0 0.2 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Peptidase_M16 PF00675.20 GAN10900.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.3 1 1 0 1 1 1 0 Insulinase (Peptidase family M16) DUF4431 PF14485.6 GAN10900.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) MOR2-PAG1_N PF14222.6 GAN10901.1 - 3.2e-194 646.9 0.8 5.2e-194 646.3 0.8 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.6 GAN10901.1 - 3.3e-71 240.3 15.7 1.7e-30 105.5 0.7 3.4 2 1 1 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_C PF14225.6 GAN10901.1 - 5.7e-61 206.6 1.8 1.2e-59 202.2 0.0 3.6 3 0 0 3 3 3 1 Cell morphogenesis C-terminal FF PF01846.19 GAN10902.1 - 6.8e-38 128.6 14.2 9e-12 45.0 0.0 6.2 6 0 0 6 6 6 5 FF domain WW PF00397.26 GAN10902.1 - 4.2e-16 58.7 19.1 1.3e-08 34.8 6.4 2.8 2 0 0 2 2 2 2 WW domain Phytochelatin PF05023.14 GAN10902.1 - 0.32 10.2 2.2 5.3 6.2 0.2 2.5 2 0 0 2 2 2 0 Phytochelatin synthase MMM1 PF10296.9 GAN10903.1 - 2e-77 260.5 4.9 2.2e-71 240.6 0.2 2.8 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Acetyltransf_10 PF13673.7 GAN10904.1 - 3.5e-10 39.9 0.0 4.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAN10904.1 - 6.2e-09 36.1 0.0 7.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAN10904.1 - 8.7e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAN10904.1 - 0.00019 21.1 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 GAN10904.1 - 0.042 14.0 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 GAN10904.1 - 0.067 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_1 PF00583.25 GAN10905.1 - 2.2e-11 44.0 0.0 2.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAN10905.1 - 1.1e-09 38.3 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAN10905.1 - 3.1e-09 37.1 0.0 5.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAN10905.1 - 9.7e-06 25.5 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAN10905.1 - 0.00096 19.8 0.0 0.0011 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAN10905.1 - 0.0076 16.3 0.1 0.037 14.1 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAN10905.1 - 0.047 13.8 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 GAN10905.1 - 0.079 13.1 0.0 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RPE65 PF03055.15 GAN10906.1 - 7.2e-87 292.5 0.0 9.3e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MBD_C PF14048.6 GAN10907.1 - 0.055 14.2 1.1 0.11 13.2 0.1 2.0 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF1641 PF07849.11 GAN10908.1 - 0.0079 16.0 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) ComZ PF10815.8 GAN10908.1 - 0.098 12.7 1.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 ComZ PPR_3 PF13812.6 GAN10908.1 - 0.14 12.3 0.0 17 5.6 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain STI1 PF17830.1 GAN10908.1 - 0.16 12.0 10.7 0.37 10.8 1.9 3.5 3 1 0 3 3 3 0 STI1 domain DNApol3-delta_C PF09115.10 GAN10908.1 - 0.19 12.3 2.3 1 9.9 0.3 2.4 2 1 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal DUF3484 PF11983.8 GAN10908.1 - 0.72 11.0 10.9 3.3 8.9 10.9 2.3 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Pribosyltran PF00156.27 GAN10909.1 - 7.5e-21 74.3 0.0 9.5e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Cmc1 PF08583.10 GAN10910.1 - 2e-13 50.2 6.7 3e-13 49.6 6.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 GAN10910.1 - 0.05 13.8 1.0 0.15 12.2 0.2 2.1 1 1 1 2 2 2 0 CHCH domain HA2 PF04408.23 GAN10911.1 - 7e-24 84.2 0.0 1.9e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAN10911.1 - 2.3e-21 76.0 0.0 6.7e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAN10911.1 - 8.1e-12 45.5 0.0 2.2e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAN10911.1 - 3.2e-08 33.6 0.1 6e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAN10911.1 - 5.4e-06 26.7 0.0 1.6e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN10911.1 - 8.6e-05 22.9 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAN10911.1 - 0.0009 18.9 0.1 0.0022 17.7 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 GAN10911.1 - 0.0036 17.1 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAN10911.1 - 0.0086 15.8 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein PhoH PF02562.16 GAN10911.1 - 0.009 15.5 0.1 0.03 13.8 0.0 1.9 3 0 0 3 3 3 1 PhoH-like protein Flavi_DEAD PF07652.14 GAN10911.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_7 PF12775.7 GAN10911.1 - 0.025 14.1 0.8 0.061 12.8 0.0 2.1 3 0 0 3 3 3 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAN10911.1 - 0.041 14.4 0.1 0.23 12.0 0.1 2.2 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 GAN10911.1 - 0.061 13.8 0.0 0.19 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAN10911.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PAP_assoc PF03828.19 GAN10912.1 - 6.7e-17 61.5 0.1 1.8e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAN10912.1 - 0.00013 22.1 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain TSC22 PF01166.18 GAN10914.1 - 0.068 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Ank_2 PF12796.7 GAN10915.1 - 5.4e-48 161.5 13.2 7e-20 71.4 0.2 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN10915.1 - 3.2e-40 136.0 7.1 4.8e-14 52.5 0.1 5.6 5 1 2 7 7 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAN10915.1 - 1.6e-31 107.3 5.8 0.0004 20.7 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 GAN10915.1 - 2e-27 94.9 10.3 1.5e-08 34.7 0.1 6.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN10915.1 - 2.2e-27 92.1 6.7 0.0065 16.9 0.0 8.9 9 0 0 9 9 8 7 Ankyrin repeat GDPD PF03009.17 GAN10915.1 - 6e-24 85.2 0.0 4.7e-23 82.2 0.0 2.3 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.19 GAN10915.1 - 4.6e-20 72.9 23.1 4.5e-10 40.0 3.1 4.0 2 1 2 4 4 4 3 SPX domain Sporozoite_P67 PF05642.11 GAN10915.1 - 0.0075 14.4 7.8 0.014 13.6 7.8 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Mucin PF01456.17 GAN10915.1 - 1.6 8.7 29.5 3.4 7.6 29.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 GAN10915.1 - 3.2 8.2 14.9 7.5 7.0 12.5 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 GAN10915.1 - 7.8 6.7 18.2 17 5.6 18.2 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Ribosomal_L14 PF00238.19 GAN10916.1 - 9e-36 122.6 0.2 1.1e-35 122.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e E1-E2_ATPase PF00122.20 GAN10918.1 - 2e-45 154.5 4.3 2e-45 154.5 4.3 3.4 5 1 1 6 6 6 1 E1-E2 ATPase Hydrolase PF00702.26 GAN10918.1 - 1.2e-22 81.3 0.4 6e-22 79.0 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAN10918.1 - 2.9e-10 39.7 0.0 8.6e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAN10918.1 - 0.00014 21.7 0.1 0.00079 19.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2818 PF10993.8 GAN10918.1 - 0.066 13.8 1.3 0.25 11.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) DUF3566 PF12089.8 GAN10919.1 - 0.0064 16.8 0.4 0.008 16.5 0.4 1.1 1 0 0 1 1 1 1 Transmembrane domain of unknown function (DUF3566) Tetraspanin PF00335.20 GAN10921.1 - 3.6e-12 46.5 6.4 5e-12 46.0 6.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1129 PF06570.11 GAN10921.1 - 0.4 10.1 7.0 0.42 10.1 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) WBP-1 PF11669.8 GAN10921.1 - 0.7 10.6 4.4 0.36 11.5 0.8 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 Tmemb_14 PF03647.13 GAN10921.1 - 1.4 9.7 5.8 0.21 12.4 1.2 2.1 2 1 0 2 2 2 0 Transmembrane proteins 14C Cyclin PF08613.11 GAN10922.1 - 2.6e-43 148.2 0.0 2.6e-43 148.2 0.0 2.6 3 0 0 3 3 3 1 Cyclin DUF5327 PF17261.2 GAN10922.1 - 5.9 7.7 25.6 5.1 7.9 2.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Mog1 PF04603.12 GAN10923.1 - 2.1e-40 138.3 2.1 3.2e-40 137.7 2.1 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SAS-6_N PF16531.5 GAN10923.1 - 0.013 16.1 0.7 0.037 14.6 0.7 1.8 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal Septin PF00735.18 GAN10924.1 - 7.7e-64 215.7 4.8 7.3e-62 209.2 4.8 2.2 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN10924.1 - 1.8e-05 24.7 2.9 4.7e-05 23.4 1.2 2.4 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN10924.1 - 0.00023 20.7 0.1 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAN10924.1 - 0.0014 19.0 0.1 0.0023 18.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 GAN10924.1 - 0.0028 17.3 0.1 0.0071 15.9 0.1 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAN10924.1 - 0.0029 17.5 0.4 0.061 13.2 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 GAN10924.1 - 0.0046 17.2 0.1 0.012 15.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAN10924.1 - 0.0048 17.1 0.2 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAN10924.1 - 0.005 16.4 0.1 0.0099 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 GAN10924.1 - 0.0064 17.0 0.5 0.013 16.0 0.5 1.8 1 1 0 1 1 1 1 ABC transporter Roc PF08477.13 GAN10924.1 - 0.01 16.0 0.2 0.053 13.7 0.1 2.2 1 1 2 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAN10924.1 - 0.016 15.0 1.2 0.37 10.6 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 GAN10924.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 GAN10924.1 - 0.024 14.4 0.6 0.068 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAN10924.1 - 0.031 14.8 0.4 0.11 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 GAN10924.1 - 0.031 14.7 0.1 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 GAN10924.1 - 0.038 13.4 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family CLP1_P PF16575.5 GAN10924.1 - 0.096 12.5 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Sigma54_activat PF00158.26 GAN10924.1 - 0.097 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 GAN10924.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 GAN10924.1 - 0.1 12.7 3.2 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain SRP54 PF00448.22 GAN10924.1 - 0.12 12.0 0.2 0.36 10.4 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.14 GAN10924.1 - 0.14 12.0 0.2 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_S17_N PF16205.5 GAN10925.1 - 1e-29 102.7 3.2 2.1e-29 101.7 3.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GAN10925.1 - 2.3e-27 94.9 0.5 3.9e-27 94.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 GAS2 PF02187.17 GAN10926.1 - 7e-12 45.3 0.1 2.9e-11 43.3 0.1 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hat1_N PF10394.9 GAN10926.1 - 0.057 13.7 2.4 0.73 10.1 0.0 4.1 3 0 0 3 3 3 0 Histone acetyl transferase HAT1 N-terminus Flu_NS2 PF00601.19 GAN10926.1 - 0.098 13.0 1.9 1.2 9.5 0.2 4.1 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) KN17_SH3 PF18131.1 GAN10926.1 - 0.14 12.3 0.1 0.48 10.6 0.1 1.9 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain CAF1A PF12253.8 GAN10926.1 - 6.3 7.0 10.7 1.8 8.8 4.9 2.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A ABATE PF07336.11 GAN10926.1 - 6.9 7.4 8.9 0.45 11.2 0.6 3.2 2 0 0 2 2 2 0 Putative stress-induced transcription regulator HAGH_C PF16123.5 GAN10927.1 - 2.1e-23 82.6 0.6 3.7e-23 81.8 0.6 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAN10927.1 - 1.6e-11 44.6 3.8 8.4e-10 39.0 3.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN10927.1 - 0.00011 21.7 2.2 0.0019 17.7 1.9 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAN10927.1 - 0.0019 18.1 0.8 0.0035 17.3 0.6 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_15 PF01793.16 GAN10928.1 - 2.2e-37 129.0 0.0 2.5e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RRM_1 PF00076.22 GAN10929.1 - 7.4e-09 35.3 0.1 1.2e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GAN10929.1 - 3.1e-07 31.1 0.1 6.5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 GAN10929.1 - 0.00016 21.6 3.6 0.00016 21.6 3.6 2.1 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 GAN10929.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAN10929.1 - 0.0016 18.4 0.1 0.0032 17.5 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_3 PF15663.5 GAN10929.1 - 0.003 17.8 0.2 0.011 15.9 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH PF00642.24 GAN10929.1 - 0.02 14.8 3.4 0.02 14.8 3.4 2.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.21 GAN10929.1 - 0.023 14.8 1.1 0.049 13.8 0.3 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_4 PF18044.1 GAN10929.1 - 0.03 14.1 3.8 0.074 12.9 3.8 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAN10929.1 - 0.042 14.3 1.9 0.042 14.3 1.9 2.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger tRNA-synt_His PF13393.6 GAN10930.1 - 8.1e-40 137.0 2.9 2.6e-35 122.2 0.0 2.4 3 0 0 3 3 3 2 Histidyl-tRNA synthetase WHEP-TRS PF00458.20 GAN10930.1 - 3.3e-15 55.9 8.5 3.3e-15 55.9 8.5 2.2 2 0 0 2 2 2 1 WHEP-TRS domain HGTP_anticodon PF03129.20 GAN10930.1 - 4.3e-12 46.0 1.7 4.6e-12 45.9 0.3 1.8 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 GAN10930.1 - 0.00012 21.7 0.1 0.00012 21.7 0.1 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 GAN10930.1 - 0.00032 19.9 0.3 0.0072 15.4 0.4 2.7 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF1820 PF08850.11 GAN10930.1 - 0.06 13.9 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) tRNA-synt_2d PF01409.20 GAN10930.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) ORF6C PF10552.9 GAN10930.1 - 0.97 9.5 4.7 0.3 11.2 0.7 2.1 2 0 0 2 2 2 0 ORF6C domain PepSY_2 PF13670.6 GAN10930.1 - 2.6 8.1 7.1 10 6.2 0.1 2.8 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Usp PF00582.26 GAN10931.1 - 1.1e-18 68.0 0.3 2.8e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Universal stress protein family SCP1201-deam PF14428.6 GAN10931.1 - 0.083 12.8 0.1 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 SCP1.201-like deaminase PCI PF01399.27 GAN10932.1 - 1.3e-08 35.2 0.7 3.1e-08 34.1 0.7 1.6 1 0 0 1 1 1 1 PCI domain CRAL_TRIO_2 PF13716.6 GAN10932.1 - 0.05 13.7 0.2 0.21 11.7 0.2 2.0 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3734 PF12536.8 GAN10932.1 - 0.16 12.3 0.1 0.35 11.2 0.1 1.5 1 0 0 1 1 1 0 Patatin phospholipase SAC3_GANP PF03399.16 GAN10933.1 - 1.1e-05 25.0 3.6 1.7e-05 24.4 3.6 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAN10933.1 - 0.00024 21.1 1.7 0.00053 20.0 0.2 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family MADF_DNA_bdg PF10545.9 GAN10933.1 - 0.02 15.2 0.5 0.081 13.3 0.1 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RICH PF05062.12 GAN10933.1 - 0.57 10.6 3.0 1.2 9.5 0.3 2.4 2 0 0 2 2 2 0 RICH domain Proteasome PF00227.26 GAN10935.1 - 4.6e-48 163.2 0.1 5.5e-48 163.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Sec1 PF00995.23 GAN10936.1 - 1.3e-132 443.9 6.7 1.5e-132 443.8 6.7 1.0 1 0 0 1 1 1 1 Sec1 family PhyH PF05721.13 GAN10937.1 - 6.3e-14 52.7 0.0 9.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ATE_C PF04377.15 GAN10938.1 - 5.8e-51 172.6 2.8 9.7e-51 171.9 2.8 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 GAN10938.1 - 1.2e-27 96.0 3.1 2.7e-27 94.9 3.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus TIP41 PF04176.13 GAN10939.1 - 5.8e-66 221.2 1.1 7.1e-66 220.9 1.1 1.1 1 0 0 1 1 1 1 TIP41-like family Cyclin PF08613.11 GAN10940.1 - 5.4e-39 134.1 0.4 8.4e-39 133.5 0.4 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN10940.1 - 0.0046 16.7 0.8 0.0087 15.8 0.8 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF1065 PF06358.11 GAN10940.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1065) bVLRF1 PF18826.1 GAN10941.1 - 2.2e-58 196.4 0.4 5.6e-58 195.0 0.4 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 GAN10941.1 - 4.1e-08 33.3 0.0 8.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_jaz PF12171.8 GAN10941.1 - 0.024 14.9 1.4 0.07 13.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.7 GAN10941.1 - 0.026 15.1 0.1 0.067 13.8 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 GAN10941.1 - 0.077 13.5 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat Dicty_REP PF05086.12 GAN10941.1 - 5.5 4.8 12.6 0.067 11.2 4.8 1.6 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Polysacc_deac_1 PF01522.21 GAN10942.1 - 1.2e-28 99.5 0.1 1.6e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN10942.1 - 3e-07 30.0 0.0 2.9e-06 26.7 0.0 2.3 1 1 2 3 3 3 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 GAN10942.1 - 6.5e-05 22.7 0.1 0.0011 18.7 0.1 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 GAN10943.1 - 1.5e-24 86.3 0.0 2.1e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN10943.1 - 2.7e-07 30.1 0.1 6.3e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 GAN10943.1 - 3.6e-06 26.8 0.6 1e-05 25.3 0.4 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) HLH PF00010.26 GAN10945.1 - 2e-13 50.0 1.9 6e-13 48.5 1.9 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RNA_pol_3_Rpc31 PF11705.8 GAN10945.1 - 0.42 10.8 11.3 0.37 11.0 9.9 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Chorion_2 PF03964.15 GAN10945.1 - 2.2 9.1 9.2 2.4 9.0 1.5 2.6 2 0 0 2 2 2 0 Chorion family 2 AAA_12 PF13087.6 GAN10946.1 - 3.4e-13 49.7 0.3 7.9e-13 48.5 0.3 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAN10946.1 - 2.4e-12 47.2 0.0 2.2e-10 40.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAN10946.1 - 7.6e-06 25.8 0.2 5.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAN10946.1 - 8.5e-06 26.2 0.1 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAN10946.1 - 0.00047 20.4 0.0 0.0035 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAN10946.1 - 0.0034 17.8 0.6 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 GAN10946.1 - 0.0037 16.7 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 GAN10946.1 - 0.0048 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAN10946.1 - 0.018 15.0 0.0 0.069 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAN10946.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAN10946.1 - 0.025 14.0 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAN10946.1 - 0.029 14.7 0.0 0.24 11.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 GAN10946.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAN10946.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GAN10946.1 - 0.088 13.0 0.1 0.53 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 GAN10946.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MYO10_CC PF16735.5 GAN10946.1 - 3.9 7.6 4.9 1 9.5 0.8 2.2 2 0 0 2 2 1 0 Unconventional myosin-X coiled coil domain EMC1_C PF07774.13 GAN10947.1 - 3.7e-71 239.2 0.0 6.3e-71 238.4 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 GAN10947.1 - 8.3e-10 38.6 2.6 1.9e-07 30.9 1.1 2.4 2 0 0 2 2 2 2 PQQ-like domain PIF1 PF05970.14 GAN10948.1 - 1.7e-32 113.0 0.0 2.7e-13 49.8 0.0 3.1 1 1 2 3 3 3 3 PIF1-like helicase AAA_16 PF13191.6 GAN10948.1 - 0.06 13.7 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Neuropep_like PF15161.6 GAN10948.1 - 0.084 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide-like Acyl-CoA_dh_M PF02770.19 GAN10949.1 - 2e-22 79.2 0.0 3.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 GAN10949.1 - 1.9e-21 76.0 0.1 3.9e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 GAN10949.1 - 3.5e-20 72.8 0.0 6.8e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAN10949.1 - 4.7e-20 72.3 0.0 7.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 GAN10949.1 - 0.0011 19.3 0.0 0.0051 17.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CAP_GLY PF01302.25 GAN10950.1 - 4.6e-22 77.8 0.3 7e-22 77.2 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain MS_channel PF00924.18 GAN10950.1 - 0.0095 15.5 0.1 0.0095 15.5 0.1 2.4 3 0 0 3 3 3 1 Mechanosensitive ion channel Phage_int_SAM_6 PF18644.1 GAN10950.1 - 0.026 14.6 2.1 0.3 11.1 0.1 2.5 1 1 1 2 2 2 0 Phage integrase SAM-like domain Spore_GerAC PF05504.11 GAN10950.1 - 0.13 12.5 6.2 0.038 14.2 1.7 2.2 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal DUF2856 PF11043.8 GAN10950.1 - 3.9 7.7 7.0 2.6 8.2 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2856) bZIP_1 PF00170.21 GAN10950.1 - 7.1 6.8 11.6 4.1 7.6 0.8 3.5 2 1 2 4 4 4 0 bZIP transcription factor PNRC PF15365.6 GAN10951.1 - 1.7e-08 34.1 7.2 4.1e-08 32.8 7.2 1.7 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif TFIIA PF03153.13 GAN10951.1 - 0.1 12.6 12.4 0.11 12.5 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_assoc2 PF16624.5 GAN10951.1 - 2.6 9.1 27.6 0.48 11.5 5.4 2.5 2 0 0 2 2 2 0 Unstructured region upstream of a zinc-finger Macoilin PF09726.9 GAN10951.1 - 4.4 5.7 17.7 4.9 5.6 17.7 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_S3_C PF00189.20 GAN10952.1 - 1.9e-22 79.6 1.4 6.1e-22 77.9 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAN10952.1 - 1.4e-12 47.2 0.1 2.4e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GAN10952.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Thioredoxin PF00085.20 GAN10953.1 - 1.6e-30 105.1 0.2 1.8e-30 105.0 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAN10953.1 - 3.9e-08 33.7 0.2 1.8e-07 31.5 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAN10953.1 - 1.3e-06 28.7 0.0 1e-05 25.8 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 GAN10953.1 - 2e-05 24.1 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GAN10953.1 - 5.2e-05 23.1 0.1 8e-05 22.5 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 GAN10953.1 - 8.7e-05 22.6 0.4 0.00017 21.7 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAN10953.1 - 0.00016 21.4 0.0 0.00018 21.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 GAN10953.1 - 0.00064 19.5 0.1 0.00093 18.9 0.1 1.3 1 1 0 1 1 1 1 Redoxin DIM1 PF02966.16 GAN10953.1 - 0.00088 19.1 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 GAN10953.1 - 0.0011 18.8 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 GAN10953.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 GAN10953.1 - 0.13 12.3 0.1 0.19 11.8 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin domain SNARE PF05739.19 GAN10954.1 - 1.6e-12 47.2 0.2 1.6e-12 47.2 0.2 2.3 2 0 0 2 2 2 1 SNARE domain SAP PF02037.27 GAN10954.1 - 8.7e-09 34.9 0.3 8.7e-09 34.9 0.3 1.7 2 0 0 2 2 2 1 SAP domain Syntaxin-5_N PF11416.8 GAN10955.1 - 1.2e-06 27.5 2.0 2.4e-06 26.6 0.8 2.2 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 GAN10955.1 - 0.00048 20.3 0.8 0.00048 20.3 0.8 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus RE_AlwI PF09491.10 GAN10955.1 - 0.0012 17.7 2.5 0.0015 17.4 2.5 1.0 1 0 0 1 1 1 1 AlwI restriction endonuclease FlxA PF14282.6 GAN10955.1 - 0.0063 16.5 7.4 0.011 15.7 7.4 1.6 1 1 0 1 1 1 1 FlxA-like protein MIP-T3_C PF17749.1 GAN10955.1 - 0.12 12.3 5.5 0.34 10.9 5.5 1.8 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DHR10 PF18595.1 GAN10955.1 - 0.22 11.6 6.0 3.7 7.6 1.3 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Lebercilin PF15619.6 GAN10955.1 - 0.25 11.0 8.8 0.36 10.5 7.5 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 GAN10955.1 - 0.3 11.6 5.3 5.7 7.5 3.4 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PRKG1_interact PF15898.5 GAN10955.1 - 0.85 10.6 9.0 0.35 11.8 4.4 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain PNP_UDP_1 PF01048.20 GAN10956.1 - 1.4e-40 139.1 0.0 1.6e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily RRM_1 PF00076.22 GAN10957.1 - 2.5e-05 24.0 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 GAN10957.1 - 5.9e-05 22.9 7.2 0.00019 21.2 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN10957.1 - 0.00081 19.2 9.3 0.0021 17.9 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAN10957.1 - 0.00088 19.1 7.7 0.0029 17.4 7.7 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAN10957.1 - 0.00091 19.5 11.3 0.0011 19.2 8.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAN10957.1 - 0.0031 17.4 10.1 0.0097 15.9 10.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAN10957.1 - 0.36 10.7 12.2 0.2 11.6 9.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAN10957.1 - 6.2 7.1 9.4 16 5.8 9.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING NDT80_PhoG PF05224.12 GAN10958.1 - 2.8e-37 128.7 0.0 1.2e-36 126.7 0.0 2.1 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ATP-synt_ab PF00006.25 GAN10959.1 - 2.3e-108 360.7 0.0 4.1e-108 359.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAN10959.1 - 2.1e-43 147.0 0.0 4.1e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAN10959.1 - 1e-12 48.4 2.3 1e-12 48.4 2.3 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Kinesin PF00225.23 GAN10960.1 - 4.1e-94 315.2 1.5 4.1e-94 315.2 1.5 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAN10960.1 - 1.5e-17 63.9 1.2 4.2e-16 59.2 0.1 2.4 2 0 0 2 2 2 2 Microtubule binding F-box-like PF12937.7 GAN10961.1 - 4.6e-06 26.4 0.0 1.4e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like ribosomal_L24 PF17136.4 GAN10962.1 - 3.9e-11 43.2 0.1 8.2e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 GAN10962.1 - 9.7e-06 25.4 0.7 1.8e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 KOW motif DUF150_C PF17384.2 GAN10962.1 - 0.13 12.5 0.2 0.42 10.8 0.3 1.8 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Nfu_N PF08712.11 GAN10963.1 - 2.7e-31 107.5 0.0 1.4e-30 105.2 0.0 2.1 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 GAN10963.1 - 7.2e-28 96.5 0.1 1.2e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 GAN10963.1 - 0.012 15.7 0.2 0.038 14.1 0.2 1.8 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus p450 PF00067.22 GAN10964.1 - 7.2e-70 236.0 0.0 1.3e-69 235.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Prefoldin_2 PF01920.20 GAN10964.1 - 3.1e-23 81.8 11.5 9.2e-23 80.2 11.5 1.9 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.9 GAN10964.1 - 0.05 13.9 7.5 0.075 13.3 1.2 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TarS_C1 PF18674.1 GAN10964.1 - 0.063 13.2 3.1 4.3 7.3 0.6 2.4 2 0 0 2 2 2 0 TarS beta-glycosyltransferase C-terminal domain 1 Leu_zip PF15294.6 GAN10964.1 - 0.073 12.6 9.1 0.23 10.9 9.1 1.8 1 1 0 1 1 1 0 Leucine zipper DivIC PF04977.15 GAN10964.1 - 0.092 12.5 10.7 0.21 11.4 5.2 2.7 2 0 0 2 2 2 0 Septum formation initiator Katanin_con80 PF13925.6 GAN10964.1 - 0.14 12.2 0.1 0.38 10.8 0.1 1.7 1 0 0 1 1 1 0 con80 domain of Katanin LPD25 PF18840.1 GAN10964.1 - 0.14 12.7 3.6 0.29 11.7 1.4 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 25 RST PF12174.8 GAN10964.1 - 0.15 12.0 0.5 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain PI3K_P85_iSH2 PF16454.5 GAN10964.1 - 0.91 9.1 11.3 2.5 7.7 8.9 2.7 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin PF02996.17 GAN10964.1 - 0.99 9.3 10.2 1.6 8.7 1.7 2.6 1 1 0 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 GAN10964.1 - 1 9.0 15.0 0.26 10.9 10.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4140 PF13600.6 GAN10964.1 - 1.2 9.6 5.6 1.9 9.0 0.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 GAN10964.1 - 2.9 8.0 11.2 0.37 10.9 6.8 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 GAN10964.1 - 4.7 7.7 8.1 3.3 8.2 0.8 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 GAN10964.1 - 5.4 7.3 10.1 11 6.3 6.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) SYF2 PF08231.12 GAN10964.1 - 7.6 6.9 11.3 5.2 7.5 6.6 2.3 2 0 0 2 2 2 0 SYF2 splicing factor Na_H_Exchanger PF00999.21 GAN10965.1 - 1.1e-65 221.9 29.2 1.4e-65 221.6 29.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 GAN10965.1 - 0.075 13.1 0.6 0.075 13.1 0.6 3.1 4 0 0 4 4 4 0 YrhC-like protein WW PF00397.26 GAN10966.1 - 2.1e-09 37.3 1.0 2.1e-09 37.3 1.0 2.8 2 0 0 2 2 2 1 WW domain SOG2 PF10428.9 GAN10967.1 - 4.4e-29 102.1 11.1 7e-18 65.1 2.3 2.3 1 1 1 2 2 2 2 RAM signalling pathway protein Oxidored-like PF09791.9 GAN10968.1 - 2.1e-20 72.1 4.2 3.7e-20 71.3 4.2 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 GAN10968.1 - 0.016 15.2 7.5 0.063 13.3 3.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5522) FAD_binding_1 PF00667.20 GAN10969.1 - 1.1e-57 195.2 0.1 1.8e-57 194.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN10969.1 - 1.6e-34 119.2 0.5 3.3e-34 118.1 0.5 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAN10969.1 - 2.1e-19 70.1 0.0 6.6e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain GGDEF_2 PF17853.1 GAN10969.1 - 0.074 13.3 0.0 4.5 7.6 0.0 2.4 2 0 0 2 2 2 0 GGDEF-like domain TPR_1 PF00515.28 GAN10971.1 - 5.6e-23 79.7 0.1 2.8e-10 39.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN10971.1 - 6.1e-22 75.9 0.3 3.5e-08 33.0 0.0 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAN10971.1 - 6.2e-21 74.5 0.2 1e-08 35.3 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAN10971.1 - 4.6e-19 67.0 0.3 5.6e-07 29.3 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAN10971.1 - 1.9e-14 52.9 0.2 7.2e-06 26.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAN10971.1 - 1.3e-13 50.3 0.0 9.3e-07 28.4 0.0 3.3 1 1 2 3 3 3 3 TPR repeat TPR_6 PF13174.6 GAN10971.1 - 7.2e-13 48.3 0.1 0.00029 21.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN10971.1 - 9.5e-13 48.5 0.1 1.4e-05 25.5 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN10971.1 - 5.7e-12 45.7 3.1 3.1e-06 27.3 0.2 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAN10971.1 - 3.8e-11 42.2 0.1 4.4e-05 23.2 0.0 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAN10971.1 - 4e-10 40.2 0.0 5.2e-06 27.0 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAN10971.1 - 7.5e-08 32.6 0.0 0.025 15.3 0.0 4.3 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAN10971.1 - 1.5e-05 24.7 0.0 0.57 10.1 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAN10971.1 - 2e-05 24.7 0.0 0.017 15.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Paf67 PF10255.9 GAN10971.1 - 5.7e-05 22.3 0.1 0.0066 15.5 0.0 2.2 1 1 1 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_20 PF14561.6 GAN10971.1 - 0.0005 20.4 0.2 0.14 12.5 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAN10971.1 - 0.0056 15.9 0.0 0.06 12.5 0.0 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF1824 PF08854.10 GAN10971.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF1824) RPN7 PF10602.9 GAN10971.1 - 0.016 15.0 1.4 2.1 8.0 0.0 3.0 2 1 2 4 4 4 0 26S proteasome subunit RPN7 SNAP PF14938.6 GAN10971.1 - 0.023 14.1 0.9 1.1 8.6 0.2 2.1 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP NSF PF02071.20 GAN10971.1 - 0.044 14.5 0.8 3.3 8.9 0.0 4.0 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat Coatomer_E PF04733.14 GAN10971.1 - 0.083 12.3 0.1 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Coatomer epsilon subunit RhoGEF PF00621.20 GAN10972.1 - 8.1e-18 65.3 0.3 1.6e-17 64.3 0.3 1.5 1 0 0 1 1 1 1 RhoGEF domain Ras PF00071.22 GAN10973.1 - 2.7e-52 176.7 0.0 3.1e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN10973.1 - 3.1e-19 69.4 0.0 4.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN10973.1 - 8.3e-09 35.1 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAN10973.1 - 2.6e-06 27.4 0.0 0.0069 16.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAN10973.1 - 7.6e-05 22.3 0.0 0.00018 21.1 0.0 1.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAN10973.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAN10973.1 - 0.067 13.0 0.4 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 GAN10973.1 - 0.11 12.1 0.0 0.39 10.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Mg_chelatase PF01078.21 GAN10973.1 - 0.7 9.2 2.4 0.48 9.8 0.2 1.9 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.25 GAN10974.1 - 7.2e-70 235.4 0.0 1.1e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN10974.1 - 1.3e-51 175.4 0.0 3.5e-51 174.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase CH PF00307.31 GAN10974.1 - 1.7e-06 28.2 0.1 4.9e-05 23.5 0.1 2.6 1 1 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 GAN10974.1 - 0.00065 19.5 12.5 0.0014 18.4 12.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 GAN10974.1 - 0.0009 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 GAN10974.1 - 0.0038 16.9 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 RIO1 PF01163.22 GAN10974.1 - 0.051 13.2 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 RIO1 family V-ATPase_C PF03223.15 GAN10975.1 - 3.8e-134 447.8 8.5 4.3e-134 447.6 8.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C CHCH PF06747.13 GAN10976.1 - 2.3e-06 27.6 7.1 4e-06 26.8 7.1 1.4 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 GAN10976.1 - 0.0013 18.8 31.0 0.0034 17.5 14.9 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2076) MTCP1 PF08991.10 GAN10976.1 - 0.027 14.7 4.9 0.043 14.0 4.9 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 GAN10976.1 - 0.034 14.1 4.8 0.075 13.1 4.8 1.7 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RskA PF10099.9 GAN10976.1 - 7.7 6.8 18.0 18 5.6 18.0 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Thaumatin PF00314.17 GAN10977.1 - 4.1e-11 42.9 5.5 4.2e-11 42.9 5.5 1.0 1 0 0 1 1 1 1 Thaumatin family SPX PF03105.19 GAN10978.1 - 7.5e-33 115.0 14.0 1e-20 75.0 8.7 2.7 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 GAN10978.1 - 1.8e-29 103.1 33.5 2.5e-29 102.7 33.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN10978.1 - 2.6e-27 95.8 41.1 6.6e-19 68.2 15.0 2.6 2 1 1 3 3 3 2 Citrate transporter DUF373 PF04123.13 GAN10978.1 - 9.7 5.5 13.6 0.66 9.4 3.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF373) EF-hand_1 PF00036.32 GAN10979.1 - 1.8e-39 130.4 6.2 1.8e-09 36.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN10979.1 - 2.1e-33 114.6 3.0 2.7e-17 62.9 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN10979.1 - 1.3e-28 96.4 4.7 2.3e-08 33.3 0.1 4.8 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 GAN10979.1 - 3e-28 97.4 9.8 2.9e-14 52.6 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAN10979.1 - 1.2e-24 84.6 6.4 2.6e-06 26.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAN10979.1 - 7.1e-13 48.7 0.0 1.7e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAN10979.1 - 8e-10 39.0 0.1 5.2e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAN10979.1 - 8.9e-09 35.2 0.8 2.1e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 GAN10979.1 - 2.2e-05 25.3 0.1 0.19 12.6 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 GAN10979.1 - 0.0022 18.0 0.0 0.062 13.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) PMBR PF09373.10 GAN10979.1 - 0.0029 17.7 0.0 8 6.8 0.0 3.7 4 0 0 4 4 4 1 Pseudomurein-binding repeat Dockerin_1 PF00404.18 GAN10979.1 - 0.0067 16.6 6.5 11 6.3 6.5 2.7 1 1 0 1 1 1 0 Dockerin type I domain DUF5580 PF17743.1 GAN10979.1 - 0.037 12.6 0.0 0.85 8.1 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF1456 PF07308.13 GAN10979.1 - 0.04 14.3 0.1 0.55 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Caleosin PF05042.13 GAN10979.1 - 0.048 13.6 0.3 17 5.3 0.0 3.1 1 1 2 3 3 3 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 GAN10979.1 - 0.11 12.8 0.5 13 6.2 0.2 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 EFhand_Ca_insen PF08726.10 GAN10979.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Copper-fist PF00649.18 GAN10980.1 - 2.1e-21 75.1 1.6 5.3e-21 73.8 1.6 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Patatin PF01734.22 GAN10980.1 - 1.3 9.2 8.8 0.64 10.2 0.1 2.8 3 0 0 3 3 3 0 Patatin-like phospholipase Band_7 PF01145.25 GAN10981.1 - 8.7e-25 87.7 4.1 1.5e-24 86.9 4.1 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 GAN10981.1 - 0.031 14.4 0.5 0.1 12.7 0.4 1.9 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain MgtE_N PF03448.17 GAN10981.1 - 0.17 12.5 2.5 16 6.2 0.5 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain VHS PF00790.19 GAN10982.1 - 1.9e-41 141.2 0.3 5e-40 136.6 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 GAN10982.1 - 5.9e-18 64.8 7.9 1.2e-17 63.8 7.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger Hrs_helical PF12210.8 GAN10982.1 - 1.5e-06 28.6 0.1 4.5e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.20 GAN10982.1 - 4.6e-06 26.2 4.7 0.012 15.4 0.3 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 GAN10982.1 - 6.5e-06 26.4 0.6 1.8e-05 24.9 0.3 2.0 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 GAN10982.1 - 0.0038 17.4 5.3 0.0094 16.2 5.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 GAN10982.1 - 0.064 13.3 9.8 29 4.8 9.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon Luteo_P1-P2 PF08467.10 GAN10982.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase FtsA PF14450.6 GAN10982.1 - 0.21 12.0 1.8 0.57 10.6 1.8 1.7 1 1 0 1 1 1 0 Cell division protein FtsA DUF202 PF02656.15 GAN10983.1 - 2.1e-15 56.9 1.2 1.2e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SdpI PF13630.6 GAN10983.1 - 0.0086 16.2 2.9 0.3 11.3 1.6 2.2 2 0 0 2 2 2 1 SdpI/YhfL protein family DUF2970 PF11174.8 GAN10983.1 - 0.057 13.3 3.3 0.67 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) RhodobacterPufX PF11511.8 GAN10983.1 - 0.067 12.8 1.9 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF3413 PF11893.8 GAN10983.1 - 0.21 10.7 4.3 1.8 7.7 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) Pex24p PF06398.11 GAN10984.1 - 5.2e-38 131.0 8.8 7.9e-38 130.4 8.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.22 GAN10984.1 - 2.6e-13 49.6 12.3 4.3e-13 48.9 12.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RDD PF06271.12 GAN10984.1 - 0.097 12.9 0.3 8 6.7 0.1 2.2 2 0 0 2 2 2 0 RDD family PRT_C PF08372.10 GAN10984.1 - 0.11 12.3 0.5 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal PHD PF00628.29 GAN10984.1 - 0.4 10.6 7.5 0.9 9.5 7.5 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 GAN10984.1 - 0.77 9.7 7.2 1.5 8.8 7.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 GAN10984.1 - 0.81 10.1 7.4 1.5 9.2 7.4 1.4 1 0 0 1 1 1 0 C1 domain zf-RING_9 PF13901.6 GAN10984.1 - 3.2 7.7 9.9 8.1 6.4 9.9 1.7 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon FAM184 PF15665.5 GAN10985.1 - 7.5 6.3 98.8 0.22 11.2 33.0 5.3 2 2 3 5 5 5 0 Family with sequence similarity 184, A and B adh_short PF00106.25 GAN10986.1 - 5e-56 189.2 0.1 6.1e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAN10986.1 - 2.3e-40 138.6 0.0 3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAN10986.1 - 1.2e-14 54.7 0.2 1.7e-14 54.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAN10986.1 - 9.8e-05 21.9 0.1 0.00017 21.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAN10986.1 - 0.00014 21.1 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAN10986.1 - 0.0016 18.4 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 GAN10986.1 - 0.023 14.8 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 GAN10986.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DrrA_P4M PF14860.6 GAN10986.1 - 0.093 12.6 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain SLS PF14611.6 GAN10987.1 - 0.057 13.2 0.1 0.062 13.1 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator OMP_b-brl_2 PF13568.6 GAN10988.1 - 0.078 13.0 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain DEAD PF00270.29 GAN10989.1 - 2.9e-45 154.2 0.0 6e-44 149.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN10989.1 - 1e-29 103.1 0.0 6.4e-29 100.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN10989.1 - 2.1e-07 31.1 0.0 9.6e-06 25.7 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 GAN10989.1 - 0.0012 18.9 2.9 0.0022 18.0 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GAN10989.1 - 0.03 14.1 1.0 0.052 13.3 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle AAA_22 PF13401.6 GAN10989.1 - 0.15 12.3 0.9 35 4.7 0.3 3.3 2 1 0 2 2 2 0 AAA domain PMSI1 PF15322.6 GAN10989.1 - 0.23 10.9 0.7 0.36 10.2 0.7 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative zf-CCHC_2 PF13696.6 GAN10989.1 - 1.5 8.7 6.0 0.45 10.4 2.3 2.0 2 0 0 2 2 2 0 Zinc knuckle HMG_box PF00505.19 GAN10990.1 - 1.3e-13 51.1 0.1 3.7e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.30 GAN10990.1 - 4.3e-13 49.5 0.2 2.9e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 GAN10990.1 - 4.7e-08 33.5 0.1 4.7e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.17 GAN10990.1 - 5.3e-08 32.8 0.5 1.2e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 GAN10990.1 - 0.00038 20.4 0.0 0.0065 16.4 0.0 2.4 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) WYL_3 PF18488.1 GAN10990.1 - 0.017 15.5 2.7 0.04 14.3 2.7 1.7 1 0 0 1 1 1 0 WYL domain DUF4611 PF15387.6 GAN10990.1 - 0.68 10.2 10.6 0.93 9.8 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF1264 PF06884.11 GAN10991.1 - 1.5e-75 252.5 1.4 1.7e-75 252.3 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Ank_2 PF12796.7 GAN10992.1 - 2.1e-28 98.7 0.9 1.8e-13 50.9 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN10992.1 - 2e-20 72.8 1.3 3.4e-05 24.3 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN10992.1 - 4.5e-17 60.4 1.5 0.0014 19.0 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 GAN10992.1 - 6e-17 61.3 4.4 0.00048 20.4 0.2 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAN10992.1 - 4.5e-11 42.8 6.4 0.002 18.4 0.6 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) DUF2431 PF10354.9 GAN10993.1 - 5.6e-50 169.9 0.0 4.5e-49 166.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) TFCD_C PF12612.8 GAN10993.1 - 8e-46 156.3 0.1 5.9e-44 150.2 0.0 3.4 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 GAN10993.1 - 1.9e-05 25.1 0.0 1.5 9.4 0.0 4.5 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 GAN10993.1 - 0.00021 21.3 5.7 0.067 13.5 0.0 5.9 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 GAN10993.1 - 0.0039 17.5 0.3 3.5 8.1 0.0 5.2 5 1 1 6 6 6 1 HEAT repeats B56 PF01603.20 GAN10993.1 - 0.025 13.6 1.5 1.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) Vac14_Fab1_bd PF12755.7 GAN10993.1 - 1.8 9.2 4.1 33 5.2 0.0 4.6 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Fra10Ac1 PF09725.9 GAN10994.1 - 2.5e-49 166.5 11.4 4.4e-49 165.7 6.4 3.0 3 0 0 3 3 3 1 Folate-sensitive fragile site protein Fra10Ac1 CotH PF08757.11 GAN10994.1 - 9.5e-37 127.2 0.0 9.5e-37 127.2 0.0 2.1 2 0 0 2 2 2 1 CotH kinase protein Usher_TcfC PF17271.2 GAN10994.1 - 0.037 12.8 0.1 0.067 12.0 0.1 1.3 1 0 0 1 1 1 0 TcfC Usher-like barrel domain DUF2197 PF09963.9 GAN10994.1 - 0.044 14.1 0.2 0.096 13.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) SID-1_RNA_chan PF13965.6 GAN10994.1 - 0.16 10.4 1.0 0.24 9.8 1.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PKD PF00801.20 GAN10995.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 PKD domain WD40 PF00400.32 GAN10996.1 - 5.1e-36 122.1 19.1 6.9e-07 29.9 0.1 6.1 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN10996.1 - 3.6e-09 36.8 0.2 0.14 12.5 0.0 3.7 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN10996.1 - 1.7e-05 24.8 0.1 3.4e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAN10996.1 - 0.0035 16.4 0.1 0.33 9.9 0.0 2.5 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAN10996.1 - 0.038 13.3 0.8 5 6.4 0.1 2.6 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 GAN10996.1 - 1.1 7.9 5.7 10 4.6 0.1 3.9 4 1 2 6 6 6 0 Nucleoporin Nup120/160 Aminotran_3 PF00202.21 GAN10997.1 - 8.9e-46 156.3 0.0 2.4e-22 79.2 0.0 3.3 1 1 1 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 GAN10997.1 - 4.1e-19 69.2 0.0 7.2e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain BATS PF06968.13 GAN10998.1 - 6.9e-20 71.0 0.1 2.2e-19 69.4 0.1 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GAN10998.1 - 7.2e-15 55.8 0.1 1e-14 55.2 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 GAN10998.1 - 0.16 12.1 0.7 0.67 10.1 0.5 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain Baculo_PEP_C PF04513.12 GAN10999.1 - 8.9e-07 29.0 21.8 0.0023 18.0 0.6 3.5 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus PhoU_div PF01865.16 GAN10999.1 - 0.0095 15.3 0.4 0.0095 15.3 0.4 3.0 1 1 2 3 3 3 1 Protein of unknown function DUF47 FlxA PF14282.6 GAN10999.1 - 0.014 15.3 4.6 0.014 15.3 4.6 4.7 3 1 2 5 5 4 0 FlxA-like protein ApoO PF09769.9 GAN10999.1 - 0.027 14.4 8.9 3.7 7.5 0.6 4.9 1 1 1 3 3 3 0 Apolipoprotein O bZIP_1 PF00170.21 GAN10999.1 - 0.034 14.3 8.4 0.24 11.5 0.4 4.1 3 1 1 4 4 4 0 bZIP transcription factor NPV_P10 PF05531.12 GAN10999.1 - 0.036 14.5 0.3 0.036 14.5 0.3 5.2 1 1 4 5 5 4 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.18 GAN10999.1 - 0.046 13.9 3.2 0.16 12.2 1.0 3.0 3 0 0 3 3 2 0 Homeobox associated leucine zipper Tmemb_cc2 PF10267.9 GAN10999.1 - 0.046 12.9 33.7 0.57 9.3 14.6 2.2 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF3584 PF12128.8 GAN10999.1 - 0.069 10.7 25.4 0.15 9.5 21.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CLZ PF16526.5 GAN10999.1 - 0.072 13.4 12.5 0.085 13.2 0.5 4.6 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fungal_TACC PF12709.7 GAN10999.1 - 0.12 12.8 0.4 0.12 12.8 0.4 4.3 3 2 2 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_2 PF07716.15 GAN10999.1 - 0.12 12.5 0.2 0.12 12.5 0.2 3.8 5 0 0 5 5 4 0 Basic region leucine zipper DUF1664 PF07889.12 GAN10999.1 - 0.17 11.9 24.4 1.3 9.0 1.4 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 GAN10999.1 - 0.22 11.7 14.4 6.3 7.0 2.5 4.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 SOGA PF11365.8 GAN10999.1 - 0.23 12.6 0.2 0.23 12.6 0.2 4.1 2 1 2 4 4 2 0 Protein SOGA DUF1515 PF07439.11 GAN10999.1 - 0.3 11.1 8.5 0.37 10.8 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) JIP_LZII PF16471.5 GAN10999.1 - 0.47 10.7 17.3 0.7 10.1 0.4 4.3 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II Tup_N PF08581.10 GAN10999.1 - 0.59 10.5 15.1 4 7.8 0.0 4.5 2 2 1 4 4 4 0 Tup N-terminal Rootletin PF15035.6 GAN10999.1 - 0.59 10.1 23.8 2.4 8.2 12.1 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.11 GAN10999.1 - 0.6 10.6 17.9 3.6 8.0 1.1 5.5 4 2 2 6 6 5 0 Flagella accessory protein C (FlaC) DUF45 PF01863.17 GAN10999.1 - 0.66 10.0 9.2 0.37 10.8 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF45 HIP1_clath_bdg PF16515.5 GAN10999.1 - 0.71 10.5 22.3 1.5 9.4 2.8 4.0 1 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 GAN10999.1 - 1.1 9.4 30.3 0.21 11.7 3.6 4.0 2 1 2 4 4 4 0 Tropomyosin like BCDHK_Adom3 PF10436.9 GAN10999.1 - 1.2 9.0 11.2 0.085 12.7 2.1 2.6 2 1 1 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HSBP1 PF06825.12 GAN10999.1 - 1.2 9.0 9.6 10 6.0 0.1 4.6 5 1 1 6 6 4 0 Heat shock factor binding protein 1 FAM76 PF16046.5 GAN10999.1 - 1.4 8.2 25.7 0.031 13.6 15.8 2.4 1 1 1 2 2 2 0 FAM76 protein PDZ_3 PF17815.1 GAN10999.1 - 1.4 8.7 6.3 0.32 10.9 2.3 1.9 2 1 0 2 2 2 0 PDZ domain Fzo_mitofusin PF04799.13 GAN10999.1 - 1.7 8.2 21.0 3 7.4 0.2 4.2 2 1 2 4 4 4 0 fzo-like conserved region Sulfotransfer_2 PF03567.14 GAN10999.1 - 2.3 8.0 8.4 0.19 11.6 1.1 2.4 2 1 1 3 3 3 0 Sulfotransferase family DivIC PF04977.15 GAN10999.1 - 3.7 7.4 17.5 0.12 12.1 1.4 4.1 4 0 0 4 4 4 0 Septum formation initiator DUF2533 PF10752.9 GAN10999.1 - 4.5 7.8 10.9 0.49 10.9 2.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2533) Macoilin PF09726.9 GAN10999.1 - 4.6 5.7 32.2 7.7 4.9 32.2 1.3 1 1 0 1 1 1 0 Macoilin family DUF2937 PF11157.8 GAN10999.1 - 6.2 6.5 10.3 3.5 7.3 1.5 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2937) Nre_C PF04895.12 GAN10999.1 - 7.2 6.6 7.0 5.8 6.9 0.0 3.9 3 1 2 6 6 6 0 Archaeal Nre, C-terminal FUSC PF04632.12 GAN10999.1 - 8.1 4.8 12.3 50 2.2 12.4 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family PDH PF02153.17 GAN11000.1 - 9.3e-17 60.9 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 GAN11000.1 - 2.9e-05 23.8 0.0 6.1e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAN11000.1 - 9.4e-05 22.9 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAN11000.1 - 0.0028 17.9 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PglD_N PF17836.1 GAN11000.1 - 0.0066 17.1 0.0 0.023 15.4 0.0 2.0 1 0 0 1 1 1 1 PglD N-terminal domain Shikimate_DH PF01488.20 GAN11000.1 - 0.039 14.0 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glycos_transf_1 PF00534.20 GAN11001.1 - 3.1e-27 95.2 0.0 5.1e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAN11001.1 - 8e-24 84.5 0.2 1.6e-23 83.5 0.1 1.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAN11001.1 - 3.7e-23 82.4 0.0 1.3e-22 80.7 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAN11001.1 - 9e-14 52.2 0.0 2.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAN11001.1 - 0.0018 18.6 0.0 0.0047 17.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Reprolysin_2 PF13574.6 GAN11002.1 - 6.9e-44 150.1 5.3 1.6e-43 148.9 5.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAN11002.1 - 1.5e-43 149.2 9.4 4.7e-43 147.6 9.4 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAN11002.1 - 1.2e-42 145.9 5.1 2.3e-42 145.0 5.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAN11002.1 - 1.2e-15 58.1 0.5 2e-14 54.2 0.1 2.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 GAN11002.1 - 4.6e-15 56.2 25.2 4.6e-15 56.2 25.2 4.3 3 2 0 3 3 3 1 Disintegrin Reprolysin PF01421.19 GAN11002.1 - 0.00032 20.7 10.0 0.0045 16.9 10.0 2.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 GAN11002.1 - 0.00041 20.6 0.0 0.0021 18.3 0.0 2.0 2 0 0 2 2 2 1 Reprolysin family propeptide IMD PF08397.11 GAN11003.1 - 0.025 14.0 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain CPSase_sm_chain PF00988.22 GAN11004.1 - 2.3e-48 163.2 0.0 3.3e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAN11004.1 - 2.9e-43 147.9 0.0 4.1e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAN11004.1 - 4.1e-05 23.4 0.5 0.36 10.5 0.0 2.9 2 1 1 3 3 3 2 Peptidase C26 Dynactin PF12455.8 GAN11005.1 - 1.2e-89 300.4 10.3 1.2e-89 300.4 10.3 6.2 6 3 1 7 7 7 1 Dynein associated protein CAP_GLY PF01302.25 GAN11005.1 - 4.1e-24 84.4 1.3 7.3e-24 83.6 1.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain BST2 PF16716.5 GAN11005.1 - 0.0037 17.8 10.0 0.0037 17.8 10.0 11.1 7 3 4 11 11 11 2 Bone marrow stromal antigen 2 Hydrolase_6 PF13344.6 GAN11006.1 - 6.2e-20 71.2 0.0 1.2e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAN11006.1 - 5.9e-12 45.5 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAN11006.1 - 0.00015 22.1 0.2 0.0009 19.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAN11006.1 - 0.00053 20.1 0.0 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 GAN11007.1 - 2.5e-48 164.3 0.2 2.8e-48 164.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPX PF03105.19 GAN11008.1 - 7.5e-33 115.0 14.0 1e-20 75.0 8.7 2.7 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 GAN11008.1 - 1.8e-29 103.1 33.5 2.5e-29 102.7 33.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAN11008.1 - 2.6e-27 95.8 41.1 6.6e-19 68.2 15.0 2.6 2 1 1 3 3 3 2 Citrate transporter DUF373 PF04123.13 GAN11008.1 - 9.7 5.5 13.6 0.66 9.4 3.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF373) EF-hand_1 PF00036.32 GAN11009.1 - 1.8e-39 130.4 6.2 1.8e-09 36.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN11009.1 - 2.1e-33 114.6 3.0 2.7e-17 62.9 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAN11009.1 - 1.3e-28 96.4 4.7 2.3e-08 33.3 0.1 4.8 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 GAN11009.1 - 3e-28 97.4 9.8 2.9e-14 52.6 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAN11009.1 - 1.2e-24 84.6 6.4 2.6e-06 26.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAN11009.1 - 7.1e-13 48.7 0.0 1.7e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAN11009.1 - 8e-10 39.0 0.1 5.2e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAN11009.1 - 8.9e-09 35.2 0.8 2.1e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 GAN11009.1 - 2.2e-05 25.3 0.1 0.19 12.6 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 GAN11009.1 - 0.0022 18.0 0.0 0.062 13.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) PMBR PF09373.10 GAN11009.1 - 0.0029 17.7 0.0 8 6.8 0.0 3.7 4 0 0 4 4 4 1 Pseudomurein-binding repeat Dockerin_1 PF00404.18 GAN11009.1 - 0.0067 16.6 6.5 11 6.3 6.5 2.7 1 1 0 1 1 1 0 Dockerin type I domain DUF5580 PF17743.1 GAN11009.1 - 0.037 12.6 0.0 0.85 8.1 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF1456 PF07308.13 GAN11009.1 - 0.04 14.3 0.1 0.55 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Caleosin PF05042.13 GAN11009.1 - 0.048 13.6 0.3 17 5.3 0.0 3.1 1 1 2 3 3 3 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 GAN11009.1 - 0.11 12.8 0.5 13 6.2 0.2 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 EFhand_Ca_insen PF08726.10 GAN11009.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Copper-fist PF00649.18 GAN11010.1 - 2.1e-21 75.1 1.6 5.3e-21 73.8 1.6 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Patatin PF01734.22 GAN11010.1 - 1.3 9.2 8.8 0.64 10.2 0.1 2.8 3 0 0 3 3 3 0 Patatin-like phospholipase RasGAP PF00616.19 GAN11012.1 - 1.9e-23 83.3 0.1 1.1e-19 70.9 0.1 3.0 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAN11012.1 - 4.8e-18 65.6 0.8 1.3e-17 64.2 0.8 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cnd1 PF12717.7 GAN11012.1 - 3.4e-05 23.9 0.3 0.0005 20.1 0.0 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CRAL_TRIO PF00650.20 GAN11012.1 - 0.00011 21.9 0.3 0.00034 20.4 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT PF02985.22 GAN11012.1 - 0.0024 18.0 4.0 2.2 8.8 0.1 4.3 3 0 0 3 3 3 2 HEAT repeat MOR2-PAG1_C PF14225.6 GAN11012.1 - 0.015 15.1 0.1 0.22 11.4 0.0 3.1 2 1 0 2 2 2 0 Cell morphogenesis C-terminal DUF3020 PF11223.8 GAN11013.1 - 7.7e-16 58.3 5.8 7.7e-16 58.3 5.8 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3020) zf-C2H2 PF00096.26 GAN11013.1 - 1.5e-05 25.2 0.2 3.9e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN11013.1 - 9.7e-05 22.9 0.7 0.00034 21.2 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 GAN11013.1 - 0.0027 17.4 0.0 0.0079 15.9 0.0 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 GAN11013.1 - 0.04 14.2 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding JmjC PF02373.22 GAN11013.1 - 0.078 13.4 2.7 7.8 7.0 0.1 2.7 3 0 0 3 3 3 0 JmjC domain, hydroxylase MPTase-PolyVal PF18818.1 GAN11013.1 - 0.45 10.6 2.8 22 5.1 0.0 2.9 3 0 0 3 3 3 0 Metallopeptidase superfamily domain TUSC2 PF15000.6 GAN11013.1 - 2.6 8.3 7.3 8.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Tumour suppressor candidate 2 zf-RING_2 PF13639.6 GAN11014.1 - 7.4e-12 45.4 7.2 1.1e-11 44.9 7.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAN11014.1 - 3.2e-09 37.0 4.0 5.7e-09 36.1 4.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAN11014.1 - 1.3e-08 34.6 7.1 2e-08 33.9 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAN11014.1 - 5.5e-07 29.3 3.6 8.3e-07 28.8 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN11014.1 - 1.4e-06 28.2 4.4 2.6e-06 27.4 4.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAN11014.1 - 2.4e-06 27.3 6.1 3.7e-06 26.7 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAN11014.1 - 5e-06 26.1 0.6 5e-06 26.1 0.6 1.7 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 GAN11014.1 - 6.2e-06 26.0 4.4 1.1e-05 25.2 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAN11014.1 - 0.00033 20.6 4.4 0.00056 19.8 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAN11014.1 - 0.002 18.1 3.9 0.0057 16.7 3.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 GAN11014.1 - 0.043 13.6 2.5 0.082 12.7 2.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-TFIIIC PF12660.7 GAN11014.1 - 0.047 13.6 1.3 0.12 12.3 1.3 1.7 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex U-box PF04564.15 GAN11014.1 - 0.062 13.5 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 U-box domain zf-C3HC4_4 PF15227.6 GAN11014.1 - 0.099 12.8 3.1 0.27 11.4 3.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING YdjO PF14169.6 GAN11014.1 - 0.13 12.0 1.6 4.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO Prok-RING_1 PF14446.6 GAN11014.1 - 0.16 11.9 3.9 0.33 10.9 0.8 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 GAN11014.1 - 0.17 12.1 2.4 0.29 11.3 2.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 GAN11014.1 - 0.19 11.4 3.3 0.3 10.7 3.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAN11014.1 - 0.5 10.2 3.5 0.87 9.4 3.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain F-box-like PF12937.7 GAN11015.1 - 2.1e-05 24.3 0.3 4.2e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAN11015.1 - 7.5e-05 22.5 0.3 0.00017 21.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAN11015.1 - 0.075 12.9 0.3 0.13 12.2 0.3 1.5 1 1 0 1 1 1 0 F-box PRANC PF09372.10 GAN11015.1 - 0.091 13.1 1.1 0.2 12.0 0.2 2.0 2 0 0 2 2 2 0 PRANC domain Ribosomal_L35p PF01632.19 GAN11016.1 - 6.2e-18 65.1 1.1 7.7e-18 64.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Methyltransf_25 PF13649.6 GAN11017.1 - 1.6e-12 47.9 0.0 6.5e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain zf-C4H2 PF10146.9 GAN11017.1 - 6.5e-10 39.7 23.9 6.5e-10 39.7 23.9 2.3 2 1 0 2 2 2 1 Zinc finger-containing protein Methyltransf_11 PF08241.12 GAN11017.1 - 1.9e-09 38.1 0.0 8e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN11017.1 - 1.6e-06 28.0 0.0 6.3e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN11017.1 - 2.7e-05 24.1 0.0 6.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN11017.1 - 0.00022 21.9 0.0 0.0012 19.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN11017.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAN11017.1 - 0.0012 18.3 1.8 0.0022 17.5 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase Baculo_PEP_C PF04513.12 GAN11017.1 - 0.24 11.4 6.0 0.26 11.3 3.2 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-K PF11802.8 GAN11017.1 - 2.1 7.8 22.9 4 6.9 22.9 1.4 1 0 0 1 1 1 0 Centromere-associated protein K SHQ1 PF04925.15 GAN11018.1 - 8.4e-69 230.6 3.5 1.4e-68 229.9 3.5 1.3 1 0 0 1 1 1 1 SHQ1 protein DUF1664 PF07889.12 GAN11018.1 - 0.86 9.7 5.6 0.45 10.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FlxA PF14282.6 GAN11018.1 - 1.2 9.2 11.3 0.19 11.7 0.8 2.6 2 0 0 2 2 2 0 FlxA-like protein PseudoU_synth_1 PF01416.20 GAN11019.1 - 6.2e-29 100.6 0.0 8.6e-27 93.7 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase SET PF00856.28 GAN11020.1 - 7.9e-20 71.9 1.9 1.6e-19 70.9 0.1 2.1 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAN11020.1 - 1.3e-12 48.5 0.9 6.6e-12 46.2 0.9 2.3 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding FAM176 PF14851.6 GAN11020.1 - 0.0046 16.6 2.6 0.011 15.4 2.6 1.6 1 0 0 1 1 1 1 FAM176 family NOA36 PF06524.12 GAN11020.1 - 0.63 9.3 8.9 1.3 8.3 8.9 1.4 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 GAN11020.1 - 1.2 9.7 19.4 4.5 7.9 0.3 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Myc_N PF01056.18 GAN11020.1 - 1.8 8.4 9.5 0.087 12.7 3.4 1.9 3 0 0 3 3 3 0 Myc amino-terminal region FAM91_C PF14648.6 GAN11020.1 - 2.9 6.6 7.2 5.2 5.8 7.3 1.3 1 1 0 1 1 1 0 FAM91 C-terminus S-antigen PF05756.11 GAN11020.1 - 3.9 7.9 7.7 6 7.3 5.0 2.3 2 0 0 2 2 2 0 S-antigen protein Radial_spoke PF04712.12 GAN11020.1 - 6 5.7 15.3 0.18 10.7 6.2 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein Cyclin PF08613.11 GAN11021.1 - 1.4e-10 41.8 0.1 1.7e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN11021.1 - 3.2e-10 39.8 0.0 6.3e-10 38.9 0.0 1.5 1 1 1 2 2 2 1 Cyclin, N-terminal domain SRP9-21 PF05486.12 GAN11022.1 - 0.00094 19.5 2.0 0.0022 18.4 0.1 2.2 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Rib PF08428.10 GAN11022.1 - 0.079 13.0 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat Ribosomal_S21e PF01249.18 GAN11023.1 - 7.3e-40 135.0 0.0 8.1e-40 134.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4576 PF15144.6 GAN11025.1 - 0.034 14.0 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Arrestin_N PF00339.29 GAN11026.1 - 2.4e-10 40.6 0.0 1.5e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAN11026.1 - 3.9e-06 27.4 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Sec_GG PF07549.14 GAN11026.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 SecD/SecF GG Motif DDRGK PF09756.9 GAN11027.1 - 1.7e-14 53.8 27.5 1.7e-14 53.8 27.5 1.5 2 0 0 2 2 2 1 DDRGK domain UBA_2 PF08587.11 GAN11027.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) GPCR_chapero_1 PF11904.8 GAN11027.1 - 0.091 12.2 11.6 0.15 11.5 11.6 1.3 1 0 0 1 1 1 0 GPCR-chaperone MMR1 PF08505.10 GAN11027.1 - 1.7 8.9 15.4 2.3 8.4 15.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein LMBR1 PF04791.16 GAN11027.1 - 3.1 6.6 7.0 3.2 6.5 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.7 GAN11027.1 - 7.2 4.6 14.5 8.8 4.3 14.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_3 PF13606.6 GAN11028.1 - 3e-11 42.5 0.1 0.0012 19.1 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 GAN11028.1 - 1.8e-09 38.0 0.0 4.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAN11028.1 - 1.4e-06 28.5 0.1 0.021 15.3 0.1 4.1 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 GAN11028.1 - 7.9e-05 22.9 0.4 0.0031 17.8 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN11028.1 - 0.014 16.0 0.0 0.54 10.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Isochorismatase PF00857.20 GAN11029.1 - 1.3e-27 97.1 0.1 1.7e-27 96.7 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family CdiA_C_tRNase PF18664.1 GAN11029.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain DUF1481 PF07356.12 GAN11029.1 - 0.023 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) BAR_2 PF10455.9 GAN11030.1 - 0.0036 16.5 0.0 0.0044 16.2 0.0 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Kelch_6 PF13964.6 GAN11031.1 - 0.00065 19.9 0.2 0.7 10.3 0.1 3.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 GAN11031.1 - 0.019 15.0 0.7 9.9 6.3 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain LPD38 PF18857.1 GAN11032.1 - 5.2e-35 121.3 0.1 5.2e-35 121.3 0.1 5.3 5 1 1 6 6 6 1 Large polyvalent protein associated domain 38 FAM76 PF16046.5 GAN11032.1 - 2.3e-06 27.2 1.8 2.3e-06 27.2 1.8 2.7 3 0 0 3 3 3 1 FAM76 protein FlxA PF14282.6 GAN11032.1 - 0.0035 17.3 6.8 0.0035 17.3 6.8 6.8 5 2 1 7 7 4 2 FlxA-like protein Prp19 PF08606.11 GAN11032.1 - 0.039 13.9 0.4 0.17 11.9 0.4 2.2 1 0 0 1 1 1 0 Prp19/Pso4-like Cu_amine_oxidN1 PF07833.11 GAN11032.1 - 0.046 14.2 0.1 0.62 10.6 0.0 3.1 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain CTX_RstB PF07459.11 GAN11032.1 - 0.081 13.2 0.1 0.29 11.4 0.1 2.0 1 0 0 1 1 1 0 CTX phage RstB protein Spectrin_like PF18373.1 GAN11032.1 - 0.21 11.7 3.9 0.25 11.4 0.3 2.8 2 0 0 2 2 2 0 Spectrin like domain DUF1759 PF03564.15 GAN11032.1 - 0.66 9.9 4.6 0.56 10.1 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Spc7 PF08317.11 GAN11032.1 - 0.69 8.7 19.1 0.061 12.2 9.1 2.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Poty_PP PF08440.10 GAN11032.1 - 2 7.4 11.9 0.077 12.1 5.2 2.0 2 0 0 2 2 2 0 Potyviridae polyprotein Med30 PF11315.8 GAN11032.1 - 2.8 8.1 8.8 0.16 12.2 1.0 2.9 2 0 0 2 2 2 0 Mediator complex subunit 30 GrpE PF01025.19 GAN11032.1 - 7.8 6.1 15.6 2.3 7.8 0.8 3.4 2 1 0 2 2 2 0 GrpE Amidase_3 PF01520.18 GAN11033.1 - 2.6e-55 187.2 0.0 3.5e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Cu_amine_oxidN1 PF07833.11 GAN11033.1 - 2.1e-05 24.9 0.1 0.024 15.1 0.0 2.5 1 1 1 2 2 2 2 Copper amine oxidase N-terminal domain Phage_holin_6_1 PF09682.10 GAN11034.1 - 7.3e-10 39.2 1.2 9e-10 38.9 1.2 1.1 1 0 0 1 1 1 1 Bacteriophage holin of superfamily 6 (Holin_LLH) LysE PF01810.18 GAN11034.1 - 0.0048 16.4 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 LysE type translocator ApbA_C PF08546.11 GAN11034.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal IalB PF06776.12 GAN11034.1 - 0.048 13.7 0.1 0.07 13.2 0.1 1.2 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein BiPBP_C PF06832.12 GAN11035.1 - 0.019 15.0 0.1 0.059 13.4 0.0 1.7 1 1 1 2 2 2 0 Penicillin-Binding Protein C-terminus Family GATase_2 PF00310.21 GAN11036.1 - 6.2e-181 601.7 0.0 8.7e-181 601.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GAN11036.1 - 6.6e-153 509.2 0.0 1.3e-152 508.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GAN11036.1 - 4.5e-111 370.8 0.0 1.3e-110 369.3 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAN11036.1 - 3.9e-85 284.2 4.2 7e-85 283.4 4.2 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GAN11036.1 - 6.5e-26 91.2 0.2 2.2e-25 89.5 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GAN11036.1 - 2.5e-23 82.0 0.2 5.8e-23 80.8 0.2 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 GAN11036.1 - 3.9e-08 33.8 0.1 2.5e-05 24.7 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN11036.1 - 4.2e-08 33.3 0.0 1.4e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAN11036.1 - 3.5e-06 26.8 0.4 0.0015 18.2 0.2 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAN11036.1 - 4.4e-06 26.3 0.3 8.3e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAN11036.1 - 5.8e-06 25.8 1.2 0.063 12.5 0.1 3.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAN11036.1 - 7.1e-05 22.3 0.2 0.00014 21.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAN11036.1 - 0.00015 20.7 1.8 0.00015 20.6 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAN11036.1 - 0.00074 18.7 0.5 0.0043 16.2 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAN11036.1 - 0.00078 18.7 0.1 0.0081 15.4 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAN11036.1 - 0.0012 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GAN11036.1 - 0.0014 19.1 0.0 1.7 9.1 0.1 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 GAN11036.1 - 0.02 14.0 0.1 0.2 10.7 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAN11036.1 - 0.046 13.0 0.2 1 8.6 0.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GATase_6 PF13522.6 GAN11036.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain FMN_dh PF01070.18 GAN11036.1 - 0.058 12.4 1.0 0.17 10.9 0.9 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Shikimate_DH PF01488.20 GAN11036.1 - 0.065 13.3 0.1 50 3.9 0.0 3.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 GAN11036.1 - 0.084 11.3 0.1 0.48 8.8 0.0 2.2 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 GAN11036.1 - 0.22 11.5 0.7 0.77 9.7 0.0 2.3 4 0 0 4 4 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus rve PF00665.26 GAN11037.1 - 6.6e-16 58.6 0.0 1.9e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GAN11037.1 - 0.0022 17.7 0.1 0.0085 15.8 0.0 2.0 3 0 0 3 3 3 1 Integrase core domain UPF0640 PF15114.6 GAN11037.1 - 0.088 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0640 Methyltransf_16 PF10294.9 GAN11038.1 - 2.4e-24 86.0 0.0 3.3e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Clathrin_lg_ch PF01086.17 GAN11039.1 - 1.3e-46 159.5 7.1 1.5e-46 159.3 7.1 1.0 1 0 0 1 1 1 1 Clathrin light chain CENP-K PF11802.8 GAN11039.1 - 0.0088 15.6 5.2 0.013 15.1 5.2 1.3 1 0 0 1 1 1 1 Centromere-associated protein K Selenoprotein_S PF06936.11 GAN11039.1 - 2.3 8.0 9.8 3.1 7.6 9.8 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DnaJ PF00226.31 GAN11040.1 - 1.1e-12 47.8 0.0 1.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain EF-hand_4 PF12763.7 GAN11041.1 - 2e-36 124.1 0.4 8.6e-17 61.0 0.0 4.8 4 2 1 5 5 5 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 GAN11041.1 - 9.5e-07 29.2 0.1 0.024 15.1 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 GAN11041.1 - 2.3e-06 26.7 0.4 4.6 7.0 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAN11041.1 - 2.5e-05 23.8 0.6 0.9 9.6 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain ArAE_2_N PF10337.9 GAN11041.1 - 0.88 8.5 10.3 1.4 7.9 10.3 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Na_Ca_ex PF01699.24 GAN11042.1 - 3e-37 127.9 42.7 1.2e-20 74.0 16.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ATP-synt_8 PF00895.20 GAN11042.1 - 0.93 10.0 3.9 1.2 9.6 0.1 2.9 2 0 0 2 2 2 0 ATP synthase protein 8 Sdh_cyt PF01127.22 GAN11042.1 - 2.4 8.2 15.5 1.6 8.7 3.8 3.5 2 1 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PGA2 PF07543.12 GAN11043.1 - 0.0047 16.9 2.7 0.011 15.7 2.7 1.5 1 0 0 1 1 1 1 Protein trafficking PGA2 EMP70 PF02990.16 GAN11044.1 - 1.3e-139 466.2 9.7 1.7e-139 465.8 9.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 G-alpha PF00503.20 GAN11045.1 - 5.8e-115 384.2 0.8 6.7e-115 384.0 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN11045.1 - 1.9e-15 56.7 0.5 3e-09 36.6 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN11045.1 - 0.00041 19.8 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAN11045.1 - 0.0092 16.2 0.0 0.61 10.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAN11045.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAN11045.1 - 0.15 12.1 0.1 2.5 8.2 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ion_trans PF00520.31 GAN11046.1 - 1.8e-10 40.5 24.5 3.2e-10 39.7 24.5 1.4 1 0 0 1 1 1 1 Ion transport protein DUF3677 PF12432.8 GAN11046.1 - 0.36 11.2 2.5 1.1 9.6 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) SHR3_chaperone PF08229.11 GAN11046.1 - 1.3 8.0 6.9 3.2 6.7 1.2 2.5 1 1 1 2 2 2 0 ER membrane protein SH3 RSN1_7TM PF02714.15 GAN11047.1 - 1.1e-76 257.7 23.8 1.8e-76 257.0 23.8 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAN11047.1 - 5.8e-35 120.4 0.4 5.8e-35 120.4 0.4 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAN11047.1 - 5.3e-34 118.0 0.5 1.3e-33 116.7 0.5 1.7 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 GAN11047.1 - 7.5e-11 42.1 0.1 2.1e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 GAN11047.1 - 0.024 14.4 0.1 10 6.0 0.1 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3464 PF11947.8 GAN11047.1 - 1.7 8.4 4.0 2.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 CRC_subunit PF08624.10 GAN11048.1 - 3e-42 144.3 0.0 6.5e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 GAN11048.1 - 4.6e-19 68.1 52.7 1.5e-08 34.4 15.2 4.2 3 1 1 4 4 4 3 PHD-finger PHD_2 PF13831.6 GAN11048.1 - 2.3 7.9 31.3 1.4 8.5 5.1 4.4 3 1 0 3 3 3 0 PHD-finger Mpv17_PMP22 PF04117.12 GAN11049.1 - 4.7e-24 84.4 0.2 8.2e-24 83.6 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family VIT1 PF01988.19 GAN11050.1 - 1.1e-74 250.9 0.0 1.3e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 VIT family DUF3792 PF12670.7 GAN11050.1 - 0.063 13.5 8.4 0.36 11.0 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) HasA PF06438.12 GAN11050.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Heme-binding protein A (HasA) DUF2207 PF09972.9 GAN11050.1 - 0.19 10.5 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 GAN11050.1 - 0.24 9.6 1.3 0.32 9.2 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lyase_8 PF02278.18 GAN11051.1 - 5e-49 167.1 3.9 8.6e-49 166.3 3.9 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 GAN11051.1 - 1.7e-23 83.1 0.5 3e-23 82.3 0.5 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 GAN11051.1 - 3e-09 37.2 0.1 7.8e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DDE_Tnp_ISL3 PF01610.17 GAN11052.1 - 0.036 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF4020 PF13212.6 GAN11052.1 - 0.063 13.1 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) HlyIII PF03006.20 GAN11053.1 - 3.6e-59 200.2 28.7 5e-59 199.7 28.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 GAN11053.1 - 0.83 9.8 7.7 0.26 11.4 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) TMEM171 PF15471.6 GAN11053.1 - 9.4 5.1 6.9 2.3 7.1 3.7 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 IKI3 PF04762.12 GAN11054.1 - 2.7e-278 925.9 0.0 5e-278 925.0 0.0 1.5 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 GAN11054.1 - 0.00038 20.7 0.5 8.4 6.8 0.0 5.8 5 2 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Latarcin PF10279.9 GAN11054.1 - 0.069 13.6 0.3 0.25 11.8 0.3 2.0 1 0 0 1 1 1 0 Latarcin precursor Ricin_B_lectin PF00652.22 GAN11055.1 - 7.7e-53 178.1 14.1 3.1e-07 30.7 0.0 13.3 10 5 5 15 15 15 14 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 GAN11055.1 - 7.7e-35 119.5 38.0 1.6e-06 28.7 0.1 14.2 11 3 3 16 16 16 11 Ricin-type beta-trefoil lectin domain-like SUIM_assoc PF16619.5 GAN11055.1 - 0.093 12.8 0.5 10 6.3 0.0 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DDE_3 PF13358.6 GAN11056.1 - 3.8e-09 36.4 0.1 4.2e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease GCS PF03074.16 GAN11056.1 - 0.023 14.1 0.2 0.024 14.0 0.2 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase RVT_1 PF00078.27 GAN11057.1 - 1.6e-20 73.6 0.4 5.9e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2312 PF10073.9 GAN11061.1 - 0.0032 17.1 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2312) Sigma70_r4 PF04545.16 GAN11062.1 - 5.1e-05 22.7 0.3 8.1e-05 22.1 0.3 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 GAN11062.1 - 0.0025 17.6 0.2 0.0047 16.7 0.2 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 GAN11062.1 - 0.015 15.1 0.2 0.026 14.3 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1804 PF08822.11 GAN11062.1 - 0.021 14.8 0.5 0.033 14.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) ELF PF03317.13 GAN11062.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 ELF protein YqjK PF13997.6 GAN11062.1 - 0.077 13.3 0.1 0.46 10.8 0.3 2.0 2 0 0 2 2 2 0 YqjK-like protein Sigma70_r4_2 PF08281.12 GAN11062.1 - 0.12 12.0 0.1 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 PBP PF01161.20 GAN11063.1 - 0.031 14.6 0.0 0.053 13.8 0.0 1.4 1 1 0 1 1 1 0 Phosphatidylethanolamine-binding protein DUF1521 PF07481.11 GAN11063.1 - 0.094 12.7 0.1 1.2 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1521) Terminase_6C PF17289.2 GAN11064.1 - 2.6e-16 60.1 0.2 4.5e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 Terminase RNaseH-like domain Terminase_6 PF03237.15 GAN11064.1 - 2.9e-13 50.0 0.0 4.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Terminase-like family UvrB PF12344.8 GAN11066.1 - 0.1 12.4 1.0 4.3 7.3 0.3 2.8 2 0 0 2 2 2 0 Ultra-violet resistance protein B MitMem_reg PF13012.6 GAN11066.1 - 0.17 12.3 2.6 1.3 9.5 2.6 2.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function PD40 PF07676.12 GAN11068.1 - 4.2e-07 29.7 8.3 0.62 10.1 0.2 5.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat WD40 PF00400.32 GAN11068.1 - 0.77 10.7 6.8 27 5.8 0.0 5.7 7 0 0 7 7 7 0 WD domain, G-beta repeat Cyt-b5 PF00173.28 GAN11069.1 - 2.3e-12 46.9 0.0 2.9e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_kinase PF01513.21 GAN11070.1 - 8.7e-62 209.0 0.0 1.4e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAN11070.1 - 0.15 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain HCNGP PF07818.13 GAN11071.1 - 3.2e-28 98.2 0.1 8e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 HCNGP-like protein Sad1_UNC PF07738.13 GAN11072.1 - 8.6e-31 106.7 0.1 2e-30 105.5 0.1 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Muskelin_N PF06588.11 GAN11072.1 - 0.015 15.2 0.2 0.039 13.9 0.2 1.7 1 0 0 1 1 1 0 Muskelin N-terminus FNIP_C PF14638.6 GAN11073.1 - 2.5e-52 177.3 2.4 3e-52 177.0 1.4 1.6 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus FNIP_M PF14637.6 GAN11073.1 - 6.1e-42 144.2 0.0 1.3e-41 143.1 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_N PF14636.6 GAN11073.1 - 1.1e-08 36.2 0.0 1.1e-08 36.2 0.0 3.9 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus Glucosamine_iso PF01182.20 GAN11075.1 - 3.2e-77 259.4 0.0 3.6e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase zf-CCHC PF00098.23 GAN11076.1 - 1.4e-10 40.7 14.4 7.8e-06 25.7 6.6 2.5 2 0 0 2 2 2 2 Zinc knuckle RRM_1 PF00076.22 GAN11076.1 - 8e-10 38.4 0.3 1.5e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 GAN11076.1 - 0.34 10.7 8.8 2.3 8.0 2.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 GAN11076.1 - 0.43 10.5 14.4 0.53 10.2 0.1 3.0 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.6 GAN11076.1 - 0.47 10.5 8.1 10 6.2 0.0 3.0 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 GAN11076.1 - 5.3 7.0 11.6 0.28 11.1 3.6 2.3 2 0 0 2 2 2 0 Zinc knuckle PPR_2 PF13041.6 GAN11077.1 - 1.8e-27 95.3 15.5 1.8e-12 47.2 0.2 7.1 4 2 3 7 7 7 5 PPR repeat family PPR_3 PF13812.6 GAN11077.1 - 1.3e-26 92.4 10.6 6.2e-09 35.8 0.1 5.4 2 2 4 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 GAN11077.1 - 2.2e-21 74.6 10.1 0.00037 20.5 0.2 7.1 7 0 0 7 7 7 6 PPR repeat PPR_1 PF12854.7 GAN11077.1 - 6.4e-19 67.3 6.0 0.0015 18.2 0.0 7.4 7 1 1 8 8 8 5 PPR repeat PPR_long PF17177.4 GAN11077.1 - 1.3e-07 31.2 0.2 0.00033 20.1 0.1 3.3 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP Clr5 PF14420.6 GAN11077.1 - 0.13 12.5 2.9 0.69 10.2 0.1 2.9 3 0 0 3 3 3 0 Clr5 domain DRIM PF07539.12 GAN11078.1 - 3.3e-179 597.2 0.6 3.3e-179 597.2 0.6 5.0 6 1 1 7 7 7 1 Down-regulated in metastasis CLASP_N PF12348.8 GAN11078.1 - 0.0063 16.1 2.1 1.5 8.3 0.0 5.0 5 1 1 6 6 6 1 CLASP N terminal DUF5623 PF18536.1 GAN11078.1 - 0.028 14.7 0.0 0.23 11.8 0.0 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) LexA_DNA_bind PF01726.16 GAN11078.1 - 0.062 13.1 0.1 0.21 11.4 0.0 1.9 1 1 0 1 1 1 0 LexA DNA binding domain LAT PF15234.6 GAN11078.1 - 0.15 11.8 0.0 0.44 10.2 0.0 1.8 1 0 0 1 1 1 0 Linker for activation of T-cells HEAT PF02985.22 GAN11078.1 - 0.3 11.4 4.2 4.7 7.7 0.1 5.0 6 0 0 6 6 6 0 HEAT repeat SWIRM PF04433.17 GAN11079.1 - 4.5e-07 30.1 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Peroxin-3 PF04882.12 GAN11080.1 - 2.6e-131 438.9 7.4 2.6e-131 438.9 7.4 1.7 2 0 0 2 2 2 1 Peroxin-3 Anp1 PF03452.14 GAN11080.1 - 6.3e-76 255.3 0.6 1.3e-75 254.3 0.6 1.5 1 0 0 1 1 1 1 Anp1 CybS PF05328.12 GAN11080.1 - 8.6e-29 99.9 0.0 1.8e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit bZIP_1 PF00170.21 GAN11080.1 - 5.5e-09 36.0 6.2 5.5e-09 36.0 6.2 3.4 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 GAN11080.1 - 3.2e-06 27.1 5.5 3.2e-06 27.1 5.5 3.0 3 0 0 3 3 3 1 Basic region leucine zipper RhoGAP PF00620.27 GAN11081.1 - 4.4e-17 62.3 0.0 6.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Glyoxal_oxid_N PF07250.11 GAN11083.1 - 2e-60 204.0 0.0 8.4e-59 198.7 0.0 2.7 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAN11083.1 - 1.6e-22 79.6 0.0 2.9e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 GAN11083.1 - 0.0024 17.9 0.5 5.5 7.1 0.0 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAN11083.1 - 0.0058 16.9 0.0 3 8.3 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAN11083.1 - 0.03 14.3 0.0 3.8 7.6 0.0 3.8 5 0 0 5 5 5 0 Kelch motif RRM_1 PF00076.22 GAN11084.1 - 2.9e-12 46.2 0.2 1.1e-11 44.4 0.1 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAN11084.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0669 PF17065.5 GAN11084.1 - 0.029 14.1 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 3Beta_HSD PF01073.19 GAN11085.1 - 2.3e-67 226.9 0.0 3e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAN11085.1 - 2.2e-33 115.7 0.0 2.7e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAN11085.1 - 4.2e-18 65.8 0.0 7.9e-17 61.6 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAN11085.1 - 5.6e-14 51.9 0.0 7.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAN11085.1 - 2e-11 43.6 0.0 3e-10 39.7 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 GAN11085.1 - 5.4e-10 39.4 0.0 7.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAN11085.1 - 4.3e-07 29.4 0.0 1.6e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAN11085.1 - 0.0005 20.0 0.1 0.024 14.5 0.1 2.4 1 1 0 1 1 1 1 KR domain RNA_pol_A_bac PF01000.26 GAN11086.1 - 7.2e-33 113.3 0.0 1.3e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAN11086.1 - 2.3e-21 75.0 0.0 3.2e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DCP1 PF06058.13 GAN11087.1 - 2.7e-35 120.8 0.1 4.3e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family SUIM_assoc PF16619.5 GAN11087.1 - 0.0033 17.4 4.5 0.0033 17.4 4.5 3.8 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 mRNA_decap_C PF16741.5 GAN11087.1 - 0.0038 16.5 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus DUF4729 PF15866.5 GAN11087.1 - 0.35 10.2 4.1 0.14 11.4 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) RasGEF PF00617.19 GAN11088.1 - 4e-40 137.9 0.1 1.4e-39 136.1 0.1 1.9 1 0 0 1 1 1 1 RasGEF domain FliJ PF02050.16 GAN11088.1 - 3 8.1 7.8 0.24 11.6 0.7 2.9 3 0 0 3 3 3 0 Flagellar FliJ protein Glyco_hydro_35 PF01301.19 GAN11089.1 - 5.2e-63 213.6 3.8 3.9e-61 207.4 3.8 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 GAN11089.1 - 4.3e-13 49.8 1.4 4.6e-07 30.4 0.2 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 GAN11089.1 - 1.4e-05 24.6 0.1 2.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 GAN11089.1 - 8.3e-05 22.2 0.0 0.00026 20.5 0.0 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) GPI-anchored PF10342.9 GAN11090.1 - 3.2e-11 43.8 0.5 8.6e-11 42.5 0.5 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MaoC_dehydrat_N PF13452.6 GAN11091.1 - 0.0037 17.4 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 GAN11091.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DSPc PF00782.20 GAN11092.1 - 5.7e-34 116.8 0.3 4.2e-32 110.7 0.3 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAN11092.1 - 0.00046 20.3 0.0 0.00074 19.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAN11092.1 - 0.0028 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 GAN11092.1 - 0.02 15.2 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain FixQ PF05545.11 GAN11093.1 - 0.049 13.6 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TraL PF07178.11 GAN11093.1 - 0.055 13.9 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 TraL protein RhoGAP PF00620.27 GAN11094.1 - 0.00011 22.0 0.3 0.00021 21.1 0.1 1.6 1 1 1 2 2 2 1 RhoGAP domain Glyco_transf_64 PF09258.10 GAN11095.1 - 2.2e-48 164.7 0.1 6.7e-48 163.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain RGS PF00615.19 GAN11097.1 - 1.2e-29 102.9 0.2 5e-29 101.0 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 GAN11097.1 - 1.4e-13 50.6 0.1 4.7e-07 29.8 0.1 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YnfE PF17452.2 GAN11098.1 - 0.00038 20.7 0.8 0.0005 20.3 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized YnfE-like Glyco_hydro_20 PF00728.22 GAN11099.1 - 5.3e-103 345.1 0.7 6.9e-103 344.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAN11099.1 - 4.3e-20 72.8 0.0 1.4e-19 71.1 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAN11099.1 - 8.5e-05 23.3 0.0 0.00021 22.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 CH PF00307.31 GAN11101.1 - 5.5e-47 158.5 2.5 2.9e-23 82.1 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 GAN11101.1 - 3.6e-13 49.4 0.2 3.6e-13 49.4 0.2 2.5 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 GAN11101.1 - 1.3e-07 31.3 0.1 5.3e-05 23.0 0.0 3.0 2 1 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.6 GAN11101.1 - 1.1e-05 25.0 0.8 0.00016 21.3 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GAN11101.1 - 0.00011 21.5 1.8 0.0029 17.1 0.0 3.5 3 0 0 3 3 3 1 EF hand CH_2 PF06294.11 GAN11101.1 - 0.00073 19.6 0.2 1.4 9.1 0.1 2.9 2 0 0 2 2 2 2 CH-like domain in sperm protein Spectrin PF00435.21 GAN11101.1 - 0.0015 19.0 3.9 0.0038 17.7 0.5 2.6 2 0 0 2 2 2 1 Spectrin repeat EF-hand_7 PF13499.6 GAN11101.1 - 0.011 16.2 3.7 0.045 14.2 3.7 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_14 PF17959.1 GAN11101.1 - 0.051 13.9 2.8 0.18 12.2 0.0 3.3 4 0 0 4 4 3 0 EF-hand domain DASH_Duo1 PF08651.10 GAN11101.1 - 0.078 12.8 0.9 0.58 10.0 0.2 2.6 1 1 1 2 2 2 0 DASH complex subunit Duo1 Apolipoprotein PF01442.18 GAN11101.1 - 0.085 12.7 1.0 0.16 11.9 1.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF489 PF04356.12 GAN11101.1 - 0.097 12.7 1.4 0.27 11.2 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF1351 PF07083.11 GAN11101.1 - 0.13 12.0 6.3 0.81 9.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1351) Seryl_tRNA_N PF02403.22 GAN11101.1 - 0.18 12.1 1.6 0.44 10.8 0.5 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 GAN11101.1 - 1.4 9.5 4.9 1 9.9 0.9 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF629 PF04780.12 GAN11102.1 - 0.065 11.8 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Sec2p PF06428.11 GAN11103.1 - 0.00057 19.8 5.1 0.00057 19.8 5.1 7.8 2 1 6 8 8 8 2 GDP/GTP exchange factor Sec2p DUF3800 PF12686.7 GAN11103.1 - 0.0026 18.4 2.0 1.6 9.4 2.0 3.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) DUF1758 PF05585.12 GAN11103.1 - 0.0056 16.5 0.5 0.017 14.9 0.5 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Abhydrolase_1 PF00561.20 GAN11104.1 - 1.9e-19 70.3 0.0 5.4e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN11104.1 - 1e-15 59.0 0.0 1.6e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.20 GAN11104.1 - 2.4e-13 50.1 0.0 6.4e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 GAN11104.1 - 1.2e-10 41.1 0.0 2.3e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAN11104.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.27 GAN11104.1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAN11104.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Chlorophyllase2 PF12740.7 GAN11104.1 - 0.1 11.5 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_2 PF01674.18 GAN11104.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_5 PF12695.7 GAN11104.1 - 0.2 11.4 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Usp PF00582.26 GAN11105.1 - 1.4e-18 67.8 0.0 1.4e-18 67.8 0.0 2.8 2 1 1 3 3 3 1 Universal stress protein family Pkinase PF00069.25 GAN11106.1 - 2e-63 214.2 0.0 2.7e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11106.1 - 1e-33 116.8 0.0 2.1e-33 115.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase C2 PF00168.30 GAN11106.1 - 1.2e-06 28.7 0.1 1.6e-05 25.2 0.1 2.4 1 1 0 1 1 1 1 C2 domain Kinase-like PF14531.6 GAN11106.1 - 0.0015 17.9 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TRAM_LAG1_CLN8 PF03798.16 GAN11107.1 - 4e-29 101.8 24.4 4e-29 101.8 24.4 2.1 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 GAN11107.1 - 2e-15 56.2 1.3 6.2e-15 54.6 1.3 1.9 1 0 0 1 1 1 1 TRAM1-like protein DUF4834 PF16118.5 GAN11107.1 - 0.1 13.6 0.6 1.3 10.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 GAN11108.1 - 9.4e-36 123.5 0.0 1.1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11108.1 - 1.4e-17 63.8 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GAN11108.1 - 0.00029 20.5 0.1 0.00058 19.5 0.1 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 GAN11108.1 - 0.0094 15.6 0.3 0.014 14.9 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 GAN11108.1 - 0.011 14.6 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GAN11108.1 - 0.012 15.6 0.3 0.021 14.7 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN11108.1 - 0.026 13.9 1.1 0.036 13.4 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAN11108.1 - 0.034 13.7 0.1 0.16 11.4 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Polysacc_deac_1 PF01522.21 GAN11109.1 - 8.4e-35 119.4 0.0 2.1e-34 118.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAN11109.1 - 0.00091 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 LytR_C PF13399.6 GAN11109.1 - 0.014 16.3 0.2 0.25 12.3 0.1 2.6 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator GxGYxYP_C PF14323.6 GAN11109.1 - 0.031 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain TetR_C_7 PF14246.6 GAN11109.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain NAD_binding_6 PF08030.12 GAN11110.1 - 1.1e-14 54.9 0.5 1.9e-13 50.8 0.5 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAN11110.1 - 7.8e-13 48.6 12.0 7.8e-13 48.6 12.0 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 GAN11110.1 - 0.0016 19.1 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 GAN11110.1 - 0.0052 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain cobW PF02492.19 GAN11111.1 - 6.8e-41 139.8 0.4 1e-40 139.2 0.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAN11111.1 - 4.2e-11 42.6 0.0 7.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAN11111.1 - 0.00013 21.9 0.2 0.081 12.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 GAN11111.1 - 0.0015 18.6 0.1 0.0056 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAN11111.1 - 0.0021 18.3 0.0 0.0053 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAN11111.1 - 0.0092 16.5 2.2 0.055 14.0 2.3 2.2 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 GAN11111.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GAN11111.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 GAN11111.1 - 0.019 14.8 0.4 0.11 12.2 0.4 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein SirA PF10747.9 GAN11111.1 - 0.021 15.2 0.3 0.054 13.8 0.3 1.6 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA SRPRB PF09439.10 GAN11111.1 - 0.026 14.0 0.3 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAN11111.1 - 0.031 14.6 0.1 0.14 12.5 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 GAN11111.1 - 0.046 13.6 0.4 0.15 11.9 0.1 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 GAN11111.1 - 0.053 13.6 0.1 0.36 10.9 0.0 2.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAN11111.1 - 0.096 12.4 1.2 9.5 6.0 0.3 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 GAN11111.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 GAN11111.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 GAN11111.1 - 0.14 12.1 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Whi5 PF08528.11 GAN11112.1 - 0.009 15.6 2.4 0.022 14.4 2.0 1.9 2 0 0 2 2 2 1 Whi5 like Gemin6 PF06372.12 GAN11113.1 - 2.8e-17 62.8 0.5 3.5e-17 62.5 0.5 1.0 1 0 0 1 1 1 1 Gemin6 protein Methyltransf_24 PF13578.6 GAN11113.1 - 0.005 17.9 0.2 0.0083 17.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF150_C PF17384.2 GAN11113.1 - 0.063 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain SM-ATX PF14438.6 GAN11113.1 - 0.082 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain tRNA_synt_1c_R1 PF04558.15 GAN11113.1 - 0.12 12.4 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Neurensin PF14927.6 GAN11114.1 - 0.06 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Neurensin Pkinase PF00069.25 GAN11115.1 - 4.3e-61 206.6 0.0 6.4e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11115.1 - 4.2e-39 134.4 0.0 1.6e-38 132.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN11115.1 - 1.7e-06 27.6 0.0 3.3e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAN11115.1 - 1.8e-05 23.8 7.0 0.00013 21.0 7.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 GAN11115.1 - 0.00077 19.1 0.1 0.0026 17.4 0.0 1.7 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 GAN11115.1 - 0.0012 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAN11115.1 - 0.0033 17.1 0.2 0.0054 16.3 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 GAN11115.1 - 0.036 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_UL25 PF01499.16 GAN11116.1 - 0.02 13.5 0.1 0.023 13.3 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Mpv17_PMP22 PF04117.12 GAN11117.1 - 3.6e-17 62.3 1.9 4.6e-17 62.0 0.7 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Lon_C PF05362.13 GAN11118.1 - 3.1e-70 235.9 0.0 5.6e-70 235.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GAN11118.1 - 4.8e-33 114.8 0.1 4.8e-33 114.8 0.1 2.9 3 1 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAN11118.1 - 3.4e-23 82.5 0.0 1.3e-22 80.6 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAN11118.1 - 7.4e-07 29.2 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 GAN11118.1 - 1e-05 25.4 0.0 2.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 GAN11118.1 - 1.2e-05 25.5 0.0 5.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAN11118.1 - 4.7e-05 23.2 0.3 0.00048 19.9 0.0 2.9 4 1 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 GAN11118.1 - 6.5e-05 22.0 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 GAN11118.1 - 0.00014 22.2 0.1 0.002 18.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAN11118.1 - 0.00059 20.3 0.1 0.0024 18.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GAN11118.1 - 0.0026 18.3 2.4 0.028 15.0 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_14 PF13173.6 GAN11118.1 - 0.004 17.2 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 GAN11118.1 - 0.0068 16.3 0.4 0.34 10.8 0.0 3.0 2 1 1 3 3 2 1 NTPase SKI PF01202.22 GAN11118.1 - 0.029 14.5 0.4 0.22 11.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase ClpB_D2-small PF10431.9 GAN11118.1 - 0.035 14.2 0.1 0.035 14.2 0.1 2.6 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein AAA_30 PF13604.6 GAN11118.1 - 0.037 13.7 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAN11118.1 - 0.061 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAN11118.1 - 0.076 13.4 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase SPASM PF13186.6 GAN11118.1 - 0.12 12.9 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain DNTTIP1_dimer PF18192.1 GAN11118.1 - 0.13 12.6 3.9 3 8.3 0.1 3.7 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain IstB_IS21 PF01695.17 GAN11118.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Exo_endo_phos PF03372.23 GAN11120.1 - 6.4e-13 48.8 0.3 1.1e-12 48.0 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 GAN11120.1 - 8.5e-12 45.0 1.4 2e-11 43.8 1.4 1.7 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 GAN11120.1 - 6.8e-05 22.7 0.1 0.0029 17.4 0.1 2.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Spore_coat_CotO PF14153.6 GAN11120.1 - 0.025 14.5 3.7 0.042 13.8 3.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO HA2 PF04408.23 GAN11121.1 - 1.9e-21 76.3 0.0 1.9e-21 76.3 0.0 4.2 5 2 0 5 5 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAN11121.1 - 3.7e-17 62.4 0.0 1.1e-16 60.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAN11121.1 - 1.2e-14 54.6 0.1 1.3e-13 51.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAN11121.1 - 5.1e-07 30.0 0.1 1.5e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GAN11121.1 - 7.4e-07 29.1 0.1 1.9e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAN11121.1 - 5.8e-05 22.9 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN11121.1 - 0.00014 22.2 0.1 0.00042 20.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAN11121.1 - 0.0029 16.7 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 GAN11121.1 - 0.0039 17.2 0.1 0.0072 16.3 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.22 GAN11121.1 - 0.016 14.9 0.3 0.042 13.5 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 GAN11121.1 - 0.034 14.2 0.2 0.32 11.0 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAN11121.1 - 0.041 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAN11121.1 - 0.046 13.9 0.0 0.27 11.4 0.0 2.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAN11121.1 - 0.047 12.9 0.2 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 GAN11121.1 - 0.062 13.8 0.0 0.73 10.4 0.0 3.0 2 0 0 2 2 1 0 AAA domain Myosin_head PF00063.21 GAN11121.1 - 0.079 11.2 0.5 0.34 9.0 0.0 2.0 2 0 0 2 2 2 0 Myosin head (motor domain) AAA_16 PF13191.6 GAN11121.1 - 0.09 13.1 0.1 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 GAN11121.1 - 0.19 12.3 3.4 0.26 11.8 0.0 2.8 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 GAN11121.1 - 0.26 11.7 0.0 0.26 11.7 0.0 3.2 4 1 0 4 4 2 0 AAA domain ATPase PF06745.13 GAN11121.1 - 0.31 10.4 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 KaiC CTD PF12815.7 GAN11121.1 - 0.55 10.8 11.4 2.5 8.7 9.3 2.9 2 1 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Pkinase PF00069.25 GAN11122.1 - 2.2e-49 168.2 0.1 2.9e-49 167.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11122.1 - 2.4e-28 99.1 0.0 3.3e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN11122.1 - 1.4e-05 24.6 0.0 0.00029 20.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 GAN11122.1 - 0.022 13.7 1.1 0.033 13.2 0.5 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase PIP49_C PF12260.8 GAN11122.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 GFO_IDH_MocA PF01408.22 GAN11122.1 - 0.09 13.6 0.0 0.34 11.7 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Nucleo_P87 PF07267.11 GAN11123.1 - 5.1 5.8 11.7 4.8 5.9 11.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1752 PF08550.10 GAN11124.1 - 1.2e-11 44.2 0.6 2.3e-11 43.3 0.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BUD22 PF09073.10 GAN11124.1 - 0.001 18.5 12.8 0.0015 18.0 12.8 1.3 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 GAN11124.1 - 0.39 10.8 14.7 0.58 10.2 14.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 GAN11124.1 - 0.43 8.6 14.1 0.64 8.1 14.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi HNF-1_N PF04814.13 GAN11124.1 - 1 9.9 17.3 0.78 10.3 6.6 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SDA1 PF05285.12 GAN11124.1 - 1.2 8.5 16.0 1.6 8.1 16.0 1.2 1 0 0 1 1 1 0 SDA1 DUF4512 PF14975.6 GAN11124.1 - 1.2 10.0 3.6 1.5 9.6 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Gelsolin PF00626.22 GAN11125.1 - 3.9e-40 135.6 0.1 1.4e-13 50.5 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat DUF1779 PF08680.10 GAN11125.1 - 0.0033 17.6 0.1 0.0066 16.7 0.1 1.5 1 0 0 1 1 1 1 TATA-box binding Acyltransferase PF01553.21 GAN11126.1 - 1.1e-23 83.4 0.0 1.5e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase US2 PF02476.15 GAN11126.1 - 0.12 13.1 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 US2 family DUF1505 PF07403.11 GAN11127.1 - 0.0012 19.0 0.0 0.0012 19.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1505) FAM176 PF14851.6 GAN11127.1 - 0.0032 17.1 0.0 0.0035 17.0 0.0 1.1 1 0 0 1 1 1 1 FAM176 family Conotoxin PF02950.17 GAN11127.1 - 0.058 14.4 0.0 0.083 13.9 0.0 1.4 1 0 0 1 1 1 0 Conotoxin Josephin PF02099.17 GAN11128.1 - 5.3e-45 153.4 0.1 9.2e-45 152.7 0.1 1.4 1 0 0 1 1 1 1 Josephin UIM PF02809.20 GAN11128.1 - 0.18 11.8 3.8 0.22 11.5 0.7 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif HLH PF00010.26 GAN11129.1 - 1.6e-13 50.4 0.2 1.6e-13 50.4 0.2 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Lyx_isomer PF07385.12 GAN11129.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 D-lyxose isomerase YabA PF06156.13 GAN11129.1 - 0.35 11.5 4.0 0.23 12.1 0.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF5345 PF17280.2 GAN11129.1 - 0.42 10.6 3.9 0.19 11.7 1.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF2756 PF10956.8 GAN11129.1 - 2.1 8.9 9.0 0.2 12.2 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) CLN3 PF02487.17 GAN11130.1 - 0.0081 15.2 1.0 0.0081 15.2 1.0 1.6 2 0 0 2 2 2 1 CLN3 protein DUF1281 PF06924.11 GAN11130.1 - 0.029 13.9 0.7 0.045 13.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Baculo_PEP_C PF04513.12 GAN11130.1 - 0.099 12.7 16.2 0.29 11.2 1.9 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 GAN11130.1 - 0.14 12.4 13.4 0.15 12.3 2.6 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) DUF948 PF06103.11 GAN11130.1 - 0.58 10.5 17.3 3 8.2 0.8 4.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 GAN11130.1 - 1.8 8.1 18.5 2.5 7.6 4.4 3.0 2 1 2 4 4 4 0 fzo-like conserved region DUF1690 PF07956.11 GAN11130.1 - 2.2 8.7 13.8 1.1 9.7 5.7 2.9 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) Mt_ATP-synt_D PF05873.12 GAN11130.1 - 3.3 7.5 10.3 1 9.2 2.8 2.8 2 1 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) bZIP_1 PF00170.21 GAN11130.1 - 4.8 7.4 7.5 5.3 7.2 1.0 3.8 3 1 1 4 4 4 0 bZIP transcription factor DUF725 PF05267.12 GAN11130.1 - 5.1 7.1 11.6 0.17 11.9 4.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF725) Csm1_N PF18504.1 GAN11130.1 - 6.2 7.2 15.1 0.8 10.1 2.2 4.0 4 1 1 5 5 5 0 Csm1 N-terminal domain DUF3573 PF12097.8 GAN11130.1 - 7.2 5.3 6.3 1.1 8.0 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Cytochrom_C1 PF02167.15 GAN11131.1 - 5.3e-98 327.1 0.0 6.6e-98 326.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAN11131.1 - 0.0022 18.3 0.0 0.0052 17.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 GAN11131.1 - 0.054 14.6 0.2 0.15 13.3 0.2 1.9 1 1 0 1 1 1 0 Cytochrome c DER1 PF04511.15 GAN11132.1 - 1.3e-45 155.7 6.8 1.5e-45 155.5 6.8 1.0 1 0 0 1 1 1 1 Der1-like family TMEM171 PF15471.6 GAN11132.1 - 0.18 10.8 0.1 0.25 10.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 SIR2 PF02146.17 GAN11133.1 - 4.3e-60 202.7 0.0 6.7e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family UvrC_HhH_N PF08459.11 GAN11133.1 - 0.003 17.5 0.1 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal UPF0121 PF03661.13 GAN11134.1 - 1.6e-43 148.9 7.0 1.7e-43 148.7 7.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Peptidase_M1 PF01433.20 GAN11135.1 - 2.6e-83 278.9 1.5 3.9e-83 278.3 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAN11135.1 - 7.5e-83 278.7 2.3 2.7e-82 276.8 0.6 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAN11135.1 - 8e-54 182.6 5.3 3.9e-52 177.2 0.5 2.3 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Yae1_N PF09811.9 GAN11135.1 - 0.072 12.8 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF2808 PF10989.8 GAN11135.1 - 0.1 12.5 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF3224 PF11528.8 GAN11135.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3224) HEAT_EZ PF13513.6 GAN11136.1 - 2.9e-06 27.7 1.9 0.29 11.7 0.1 5.3 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 GAN11136.1 - 4.9e-06 26.4 7.8 1.6e-05 24.8 0.1 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GAN11136.1 - 0.0016 18.5 0.0 0.0082 16.2 0.0 2.2 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Npa1 PF11707.8 GAN11136.1 - 0.041 13.2 0.4 0.66 9.3 0.4 2.9 1 1 0 1 1 1 0 Ribosome 60S biogenesis N-terminal HEAT PF02985.22 GAN11136.1 - 0.066 13.5 1.0 5.2 7.6 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat MFS_1 PF07690.16 GAN11137.1 - 9.9e-12 44.4 29.2 9.9e-12 44.4 29.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAN11137.1 - 1.1e-09 38.1 2.9 1.1e-09 38.1 2.9 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 SMC_N PF02463.19 GAN11139.1 - 2.9e-69 232.9 9.5 7.7e-38 130.1 0.1 4.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAN11139.1 - 7.8e-19 68.1 0.1 4.2e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 GAN11139.1 - 2.3e-13 51.1 15.2 2.3e-13 51.1 15.2 6.6 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 GAN11139.1 - 1.4e-11 44.8 0.9 5.9e-05 23.0 0.1 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAN11139.1 - 0.00037 20.2 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain UDG PF03167.19 GAN11140.1 - 3.2e-26 92.2 0.1 4.7e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Polysacc_deac_1 PF01522.21 GAN11140.1 - 0.054 13.4 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide deacetylase PH PF00169.29 GAN11143.1 - 1.3e-08 35.2 0.1 0.00034 21.1 0.0 2.9 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 GAN11143.1 - 8.2e-05 23.0 0.2 0.0022 18.4 0.0 3.3 2 2 0 2 2 2 1 Pleckstrin homology domain RNA_bind PF08675.11 GAN11143.1 - 0.00011 22.1 0.0 0.0022 18.0 0.0 2.5 2 0 0 2 2 2 1 RNA binding domain NCBP3 PF10309.9 GAN11143.1 - 0.00061 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Cellulase PF00150.18 GAN11144.1 - 9.9e-25 87.5 2.5 2e-24 86.5 2.5 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 GAN11144.1 - 1.6e-15 57.4 0.2 5.1e-15 55.8 0.1 1.9 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 GAN11144.1 - 0.00061 19.2 0.0 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 GAN11144.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Trehalase PF01204.18 GAN11145.1 - 1.6e-175 584.9 0.8 1.9e-175 584.5 0.8 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 GAN11145.1 - 1e-15 57.1 1.6 2.2e-15 56.1 1.6 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain YkyA PF10368.9 GAN11145.1 - 0.18 11.4 2.7 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein GST_N_3 PF13417.6 GAN11146.1 - 1.4e-19 70.3 0.0 2.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAN11146.1 - 6.5e-17 61.6 1.7 7.4e-16 58.3 0.1 2.8 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN11146.1 - 5.6e-16 58.6 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 GAN11146.1 - 1.3e-11 45.1 0.1 2.3e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAN11146.1 - 7.8e-07 29.2 0.1 1.5e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN11146.1 - 1.2e-06 28.4 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN11146.1 - 4.4e-05 23.6 0.1 0.00015 21.9 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAN11146.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DNTTIP1_dimer PF18192.1 GAN11146.1 - 0.026 14.8 0.2 0.064 13.6 0.2 1.6 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain eIF3_subunit PF08597.10 GAN11147.1 - 2e-48 165.4 40.6 2.2e-48 165.3 40.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3861 PF12977.7 GAN11147.1 - 0.091 12.9 2.3 0.16 12.1 0.1 2.4 2 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) SAT PF16073.5 GAN11147.1 - 1 9.1 3.9 0.2 11.4 0.5 1.5 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis CENP-F_leu_zip PF10473.9 GAN11148.1 - 2.8e-05 24.2 6.7 2.8e-05 24.2 6.7 3.4 3 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 GAN11148.1 - 0.0098 16.1 4.0 0.0098 16.1 4.0 3.2 2 1 0 3 3 3 2 Autophagy protein 16 (ATG16) Fungal_trans PF04082.18 GAN11148.1 - 0.052 12.6 2.2 0.11 11.5 0.9 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Thermopsin PF05317.11 GAN11148.1 - 0.18 11.2 0.3 0.32 10.4 0.3 1.4 1 0 0 1 1 1 0 Thermopsin DUF3535 PF12054.8 GAN11149.1 - 1.4e-113 380.4 5.1 3.3e-112 375.9 0.3 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 GAN11149.1 - 1.1e-61 208.5 0.0 2.7e-61 207.2 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAN11149.1 - 6.9e-16 58.6 0.0 2.2e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 GAN11149.1 - 4.7e-10 38.9 20.7 0.0054 16.9 0.5 9.6 10 1 1 11 11 11 3 HEAT repeat TAF6_C PF07571.13 GAN11149.1 - 8.4e-06 26.0 0.4 0.42 11.0 0.0 5.1 6 0 0 6 6 6 2 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 GAN11149.1 - 0.00087 19.8 0.1 2.1 9.0 0.1 3.6 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN11149.1 - 0.0021 18.1 0.2 15 5.6 0.0 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAN11149.1 - 0.0096 16.3 7.0 0.01 16.2 0.4 4.5 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 GAN11149.1 - 0.24 12.0 12.3 5.6 7.6 0.3 5.8 6 0 0 6 6 6 0 HEAT-like repeat LAG1-DNAbind PF09271.11 GAN11150.1 - 2.8e-49 167.6 0.4 2.8e-49 167.6 0.4 3.3 4 0 0 4 4 4 1 LAG1, DNA binding BTD PF09270.10 GAN11150.1 - 7e-23 81.5 0.0 3.9e-21 75.9 0.0 3.2 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain TIG PF01833.24 GAN11150.1 - 0.0092 16.0 0.0 0.061 13.4 0.0 2.4 2 0 0 2 2 2 1 IPT/TIG domain tRNA_anti-codon PF01336.25 GAN11151.1 - 2e-09 37.3 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 GAN11151.1 - 1.8e-05 23.8 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Telomere regulation protein Stn1 STN1_2 PF09170.10 GAN11151.1 - 5.9e-05 23.3 1.0 0.00012 22.4 1.0 1.4 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti_2 PF13742.6 GAN11151.1 - 0.033 14.4 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RMI2 PF16100.5 GAN11151.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 CDC24_OB3 PF17244.2 GAN11151.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Adeno_E3_CR2 PF02439.15 GAN11151.1 - 0.26 11.1 2.1 0.7 9.7 2.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Melibiase_C PF17801.1 GAN11152.1 - 1.1e-11 44.6 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2 PF16499.5 GAN11152.1 - 1.1e-11 44.4 1.8 7.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Glyco_hydro_31 PF01055.26 GAN11152.1 - 1.9e-07 30.6 0.2 2.9e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 GAN11152.1 - 9e-06 24.9 0.2 8.9e-05 21.6 0.0 2.2 2 1 0 2 2 2 1 Melibiase DDHD PF02862.17 GAN11153.1 - 3.2e-48 164.8 0.0 3.2e-48 164.8 0.0 3.1 2 1 0 2 2 2 1 DDHD domain WWE PF02825.20 GAN11153.1 - 2.3e-05 24.9 0.6 0.0034 17.9 0.0 2.8 1 1 1 2 2 2 2 WWE domain TRAP_alpha PF03896.16 GAN11153.1 - 1.1 8.3 6.3 2.6 7.2 6.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pro_isomerase PF00160.21 GAN11154.1 - 1.1e-51 175.2 0.7 3.2e-51 173.7 0.1 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 GAN11154.1 - 1.7e-06 27.6 2.9 1.7e-06 27.6 2.9 2.6 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 GAN11154.1 - 8.2e-06 25.9 0.3 5.9e-05 23.1 0.1 2.6 2 1 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 GAN11154.1 - 2.3e-05 24.5 0.1 0.0062 16.7 0.0 2.8 2 1 0 2 2 2 2 U-box domain zf-Nse PF11789.8 GAN11154.1 - 0.18 11.7 0.4 0.82 9.5 0.4 2.1 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit GATA PF00320.27 GAN11155.1 - 8.1e-17 60.5 4.8 2.1e-16 59.2 4.8 1.8 1 0 0 1 1 1 1 GATA zinc finger CDC45 PF02724.14 GAN11155.1 - 2.8e-06 25.9 6.0 3.5e-06 25.6 6.0 1.2 1 0 0 1 1 1 1 CDC45-like protein Zn-ribbon_8 PF09723.10 GAN11155.1 - 0.041 14.0 0.3 0.089 12.9 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain NOA36 PF06524.12 GAN11155.1 - 0.047 13.0 12.9 0.082 12.2 12.9 1.4 1 0 0 1 1 1 0 NOA36 protein zf-3CxxC PF13695.6 GAN11155.1 - 0.056 13.9 6.3 0.74 10.3 1.2 2.8 2 1 0 2 2 2 0 Zinc-binding domain Muraidase PF11860.8 GAN11155.1 - 0.073 13.3 2.5 0.15 12.3 2.5 1.4 1 0 0 1 1 1 0 N-acetylmuramidase FAM176 PF14851.6 GAN11155.1 - 0.1 12.3 8.7 0.24 11.0 8.7 1.6 1 0 0 1 1 1 0 FAM176 family FAM163 PF15069.6 GAN11155.1 - 0.48 10.9 7.9 0.21 12.0 3.6 2.5 1 1 1 3 3 3 0 FAM163 family DUF4611 PF15387.6 GAN11155.1 - 0.76 10.0 10.5 2.3 8.5 10.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nudix_N_2 PF14803.6 GAN11155.1 - 1.1 9.2 3.3 2.4 8.1 3.3 1.6 1 0 0 1 1 1 0 Nudix N-terminal CENP-B_dimeris PF09026.10 GAN11155.1 - 3.3 8.1 15.1 6.6 7.2 15.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain OrfB_Zn_ribbon PF07282.11 GAN11155.1 - 3.9 7.5 6.1 0.95 9.4 1.4 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RRN3 PF05327.11 GAN11155.1 - 4.2 5.8 13.1 6.4 5.2 13.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 S-antigen PF05756.11 GAN11155.1 - 7.6 7.0 11.4 16 6.0 11.4 1.5 1 0 0 1 1 1 0 S-antigen protein Peptidase_M41 PF01434.18 GAN11156.1 - 9.3e-66 221.3 0.8 9.3e-66 221.3 0.8 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 GAN11156.1 - 6.6e-43 146.3 0.0 2.3e-42 144.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAN11156.1 - 2e-11 43.5 0.0 4.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAN11156.1 - 1.5e-06 28.2 0.0 5e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAN11156.1 - 1.1e-05 25.7 1.3 0.013 15.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 GAN11156.1 - 1.6e-05 25.3 1.0 0.00029 21.3 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 GAN11156.1 - 2.2e-05 23.9 0.0 5.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GAN11156.1 - 9e-05 22.3 0.0 0.00034 20.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAN11156.1 - 0.00023 21.3 0.0 0.0013 18.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAN11156.1 - 0.0011 18.2 0.0 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 GAN11156.1 - 0.0053 16.2 0.5 0.014 14.8 0.5 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAN11156.1 - 0.0066 17.0 0.0 0.019 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAN11156.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 GAN11156.1 - 0.013 15.1 0.7 0.34 10.5 0.3 2.6 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAN11156.1 - 0.017 15.1 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAN11156.1 - 0.024 14.9 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAN11156.1 - 0.025 14.7 0.1 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAN11156.1 - 0.026 14.2 0.1 0.34 10.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 GAN11156.1 - 0.038 13.9 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 GAN11156.1 - 0.05 13.6 0.2 0.17 11.9 0.0 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAN11156.1 - 0.067 12.7 0.3 0.3 10.6 0.1 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAN11156.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.6 GAN11156.1 - 0.13 11.9 0.5 6.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Peptidase M50B-like ATPase PF06745.13 GAN11156.1 - 0.15 11.4 4.8 0.86 8.9 0.2 3.7 4 1 0 4 4 4 0 KaiC Zeta_toxin PF06414.12 GAN11156.1 - 0.25 10.6 3.5 0.61 9.3 0.5 2.7 2 1 1 3 3 3 0 Zeta toxin AAA_19 PF13245.6 GAN11156.1 - 0.52 10.6 2.2 1.7 8.9 0.3 2.6 3 0 0 3 3 3 0 AAA domain Apolipoprotein PF01442.18 GAN11157.1 - 0.00012 22.0 12.2 0.00016 21.6 12.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain AIF-MLS PF14962.6 GAN11157.1 - 0.02 14.8 7.7 0.029 14.3 7.7 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence ATP-synt_B PF00430.18 GAN11157.1 - 0.027 14.6 19.0 0.049 13.7 19.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) YtxH PF12732.7 GAN11157.1 - 0.047 14.2 24.8 0.31 11.6 8.1 2.4 1 1 1 2 2 2 0 YtxH-like protein Phasin PF05597.11 GAN11157.1 - 0.11 12.5 13.6 0.26 11.3 4.6 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NMD3 PF04981.13 GAN11157.1 - 0.23 10.9 4.3 0.33 10.4 4.3 1.2 1 0 0 1 1 1 0 NMD3 family DUF883 PF05957.13 GAN11157.1 - 2.3 8.9 13.8 2.2 9.0 5.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3072 PF11272.8 GAN11157.1 - 4.3 7.3 11.4 5.5 7.0 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3072) DUF4407 PF14362.6 GAN11157.1 - 6 6.1 11.8 6.9 5.9 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Grg1 PF11034.8 GAN11157.1 - 6.4 7.1 28.5 0.52 10.6 6.4 3.5 1 1 2 3 3 3 0 Glucose-repressible protein Grg1 COX3 PF00510.18 GAN11158.1 - 1.3e-51 176.0 6.3 3.5e-51 174.5 6.3 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III ATP-synt_A PF00119.20 GAN11159.1 - 9.4e-47 159.7 23.6 1e-46 159.5 23.6 1.0 1 0 0 1 1 1 1 ATP synthase A chain COX2 PF00116.20 GAN11160.1 - 3.3e-63 210.9 0.0 6.3e-63 210.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 GAN11160.1 - 1.9e-33 114.4 1.4 3.3e-33 113.7 1.4 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DUF2953 PF11167.8 GAN11160.1 - 5.3 7.2 5.9 4.2 7.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Pkinase PF00069.25 GAN11161.1 - 4.6e-53 180.3 0.4 2.7e-52 177.7 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11161.1 - 2.4e-22 79.5 0.0 4.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAN11161.1 - 0.00071 19.6 0.2 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAN11161.1 - 0.96 9.0 9.9 0.04 13.5 1.7 2.5 2 1 0 2 2 2 0 RIO1 family ARID PF01388.21 GAN11162.1 - 5.4e-20 71.9 0.0 1.5e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain FOXP-CC PF16159.5 GAN11162.1 - 3.3e-05 24.4 4.7 0.022 15.4 0.9 2.8 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 GAN11162.1 - 0.02 15.3 3.8 4 8.1 0.5 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type LIM PF00412.22 GAN11163.1 - 9e-56 185.9 44.7 4.4e-18 65.2 4.7 4.2 4 0 0 4 4 4 4 LIM domain AMP-binding PF00501.28 GAN11164.1 - 1.1e-101 340.5 0.0 1.6e-101 340.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAN11164.1 - 0.0016 19.4 0.1 0.0048 17.8 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIIF_alpha PF05793.12 GAN11165.1 - 1.9e-20 73.0 66.5 1.9e-17 63.1 66.5 3.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L26 PF16906.5 GAN11166.1 - 9.5e-36 122.1 3.5 1.3e-35 121.7 3.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAN11166.1 - 1.5e-10 40.6 2.9 3.4e-10 39.5 2.9 1.6 1 0 0 1 1 1 1 KOW motif DUF1442 PF07279.11 GAN11166.1 - 0.0092 15.3 1.5 0.011 15.0 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Aa_trans PF01490.18 GAN11168.1 - 2.1e-15 56.3 28.6 4.5e-15 55.3 28.6 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAN11168.1 - 9e-07 28.3 4.9 9e-07 28.3 4.9 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SMK-1 PF04802.15 GAN11169.1 - 1.2e-59 201.4 2.2 2.4e-59 200.4 2.2 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 NMO PF03060.15 GAN11170.1 - 1.3e-55 189.1 0.8 2.2e-54 185.1 0.8 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAN11170.1 - 3.1e-13 49.4 0.1 1e-05 24.7 0.3 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 GAN11170.1 - 0.0025 17.0 0.7 0.012 14.8 0.1 2.3 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 GAN11170.1 - 0.0076 15.3 0.3 0.018 14.1 0.3 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAN11170.1 - 0.025 13.7 1.6 0.056 12.6 0.5 2.0 2 1 0 2 2 2 0 Conserved region in glutamate synthase His_biosynth PF00977.21 GAN11170.1 - 0.028 13.9 0.4 0.42 10.0 0.1 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein PI3_PI4_kinase PF00454.27 GAN11171.1 - 1.2e-50 172.7 0.0 4.7e-48 164.2 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAN11171.1 - 8.4e-42 142.7 0.1 1.8e-41 141.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 GAN11171.1 - 4.1e-38 130.5 0.1 8.9e-38 129.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 GAN11171.1 - 0.0057 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Linker_histone PF00538.19 GAN11172.1 - 3.6e-23 81.7 0.1 3.6e-23 81.7 0.1 1.6 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF3446 PF11928.8 GAN11172.1 - 0.097 13.0 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain RibD_C PF01872.17 GAN11173.1 - 5.8e-33 114.4 0.0 6.6e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Rib_5-P_isom_A PF06026.14 GAN11174.1 - 3.4e-61 205.8 0.1 4.1e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GAN11174.1 - 0.0018 18.3 0.0 0.034 14.1 0.0 2.1 2 0 0 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 GAN11174.1 - 0.003 16.7 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative sugar-binding domain DUF1522 PF07482.11 GAN11174.1 - 0.055 13.8 0.0 0.56 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) WD40 PF00400.32 GAN11175.1 - 1.2e-28 98.8 11.1 2.8e-07 31.1 0.2 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Bromodomain PF00439.25 GAN11175.1 - 6.3e-12 45.4 0.2 1.4e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 GAN11175.1 - 1.4e-08 34.9 0.2 0.22 11.9 0.0 5.1 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN11175.1 - 0.00022 20.3 0.6 0.79 8.6 0.0 4.2 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Med31 PF05669.12 GAN11175.1 - 0.029 14.3 0.2 0.066 13.2 0.2 1.5 1 0 0 1 1 1 0 SOH1 Auxin_resp PF06507.13 GAN11175.1 - 0.044 14.1 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Auxin response factor Nup160 PF11715.8 GAN11175.1 - 0.26 9.9 3.2 0.75 8.4 0.1 2.9 3 1 0 3 3 3 0 Nucleoporin Nup120/160 BATS PF06968.13 GAN11176.1 - 6.9e-20 71.0 0.1 2.2e-19 69.4 0.1 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GAN11176.1 - 7.2e-15 55.8 0.1 1e-14 55.2 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 GAN11176.1 - 0.16 12.1 0.7 0.67 10.1 0.5 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain Aminotran_3 PF00202.21 GAN11177.1 - 8.9e-46 156.3 0.0 2.4e-22 79.2 0.0 3.3 1 1 1 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 GAN11177.1 - 4.1e-19 69.2 0.0 7.2e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain WD40 PF00400.32 GAN11178.1 - 5.4e-18 65.0 4.7 2.3e-07 31.4 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN11178.1 - 8.4e-10 38.8 0.0 0.048 14.0 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAN11178.1 - 0.00076 18.5 0.1 0.15 10.9 0.0 2.4 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAN11178.1 - 0.0032 17.4 0.0 0.0086 16.0 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAN11178.1 - 0.015 14.7 0.2 1.2 8.3 0.1 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal NUFIP1 PF10453.9 GAN11179.1 - 1.3e-06 28.2 5.1 4.6e-06 26.4 3.6 2.5 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Retrotrans_gag PF03732.17 GAN11179.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF726 PF05277.12 GAN11180.1 - 1.7e-67 227.8 0.1 3.1e-47 161.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 GAN11180.1 - 6.8 6.8 12.1 0.44 10.6 6.1 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III BTB_2 PF02214.22 GAN11181.1 - 2.8e-13 50.0 0.4 7.3e-13 48.7 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain BBS2_Mid PF14783.6 GAN11182.1 - 0.29 11.2 0.8 2.3 8.3 0.2 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 GAN11182.1 - 1.6 9.7 5.7 11 7.1 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Abhydrolase_1 PF00561.20 GAN11183.1 - 5.1e-06 26.3 1.0 5.6e-05 22.9 0.1 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 GAN11183.1 - 0.00017 21.4 0.1 0.00035 20.4 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 GAN11183.1 - 0.00048 20.1 0.0 0.00079 19.3 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 GAN11183.1 - 0.0027 17.3 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 GAN11183.1 - 0.0039 16.5 0.0 0.079 12.3 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 GAN11183.1 - 0.0047 17.6 0.1 0.0073 16.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 GAN11183.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase SET PF00856.28 GAN11184.1 - 9.7e-06 26.1 0.9 2.6e-05 24.7 0.9 1.8 1 1 0 1 1 1 1 SET domain FYVE_2 PF02318.16 GAN11184.1 - 1 9.6 20.5 0.53 10.5 6.1 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger F-box-like PF12937.7 GAN11185.1 - 0.0025 17.7 0.3 0.0057 16.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAN11185.1 - 0.29 11.6 15.9 0.16 12.4 0.3 5.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) COX7a PF02238.15 GAN11186.1 - 1.2e-16 60.8 0.1 1.6e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Oxysterol_BP PF01237.18 GAN11187.1 - 4.4e-116 387.8 1.2 1.4e-115 386.1 1.2 1.9 1 0 0 1 1 1 1 Oxysterol-binding protein EF-hand_7 PF13499.6 GAN11187.1 - 3.9e-22 78.5 2.5 1.5e-10 41.4 0.0 4.8 4 1 0 4 4 4 3 EF-hand domain pair PH_8 PF15409.6 GAN11187.1 - 2.5e-20 72.5 0.2 7.2e-20 71.1 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_1 PF00036.32 GAN11187.1 - 2.6e-20 70.4 4.0 6.3e-05 22.2 0.1 5.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAN11187.1 - 2.3e-19 67.6 5.0 6.5e-05 22.5 0.0 5.4 5 0 0 5 5 4 4 EF-hand domain EF-hand_5 PF13202.6 GAN11187.1 - 3.2e-18 64.3 3.8 1.8e-05 24.0 0.0 4.8 4 0 0 4 4 4 4 EF hand NUDIX PF00293.28 GAN11187.1 - 1.7e-16 60.5 0.1 1.8e-15 57.1 0.1 2.5 2 0 0 2 2 2 1 NUDIX domain EF-hand_8 PF13833.6 GAN11187.1 - 8.2e-15 54.4 2.2 7.2e-09 35.4 0.1 5.1 4 2 1 5 5 4 3 EF-hand domain pair PH PF00169.29 GAN11187.1 - 5.6e-07 30.0 1.2 2.3e-06 28.0 0.1 2.6 2 0 0 2 2 2 1 PH domain GOLD_2 PF13897.6 GAN11187.1 - 4.6e-06 27.2 0.6 0.003 18.1 0.6 2.9 1 1 0 1 1 1 1 Golgi-dynamics membrane-trafficking NUDIX-like PF09296.11 GAN11187.1 - 2.2e-05 25.0 0.0 9.3e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 GAN11187.1 - 2.7e-05 23.7 2.7 6.1e-05 22.6 2.7 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PH_11 PF15413.6 GAN11187.1 - 0.025 15.0 1.8 0.39 11.1 1.8 3.1 1 1 0 1 1 1 0 Pleckstrin homology domain EMP24_GP25L PF01105.24 GAN11187.1 - 0.083 12.8 2.1 0.088 12.7 0.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Caleosin PF05042.13 GAN11187.1 - 0.22 11.4 1.7 0.44 10.5 0.3 2.2 2 0 0 2 2 2 0 Caleosin related protein Ank_4 PF13637.6 GAN11188.1 - 2.1e-14 53.6 0.0 6.1e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN11188.1 - 2.6e-11 44.0 0.1 5e-11 43.1 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAN11188.1 - 1.6e-08 34.7 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAN11188.1 - 6.5e-06 26.1 0.0 8.4e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAN11188.1 - 7.4e-06 26.2 0.0 0.00025 21.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat DEC-1_N PF04625.13 GAN11188.1 - 0.041 12.9 0.1 0.049 12.7 0.1 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PUB_1 PF18486.1 GAN11188.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Tim54 PF11711.8 GAN11189.1 - 1e-57 195.7 0.6 1.5e-57 195.1 0.6 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 LMBR1 PF04791.16 GAN11189.1 - 0.077 11.9 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4322 PF14210.6 GAN11189.1 - 0.091 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) Aa_trans PF01490.18 GAN11190.1 - 1.8e-81 274.0 30.1 2.1e-81 273.7 30.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2542 PF10808.8 GAN11190.1 - 0.58 10.7 3.1 26 5.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2542) FAM104 PF15434.6 GAN11190.1 - 1.5 9.4 9.5 0.6 10.7 5.4 2.1 2 0 0 2 2 2 0 Family 104 NAD_binding_10 PF13460.6 GAN11191.1 - 1.6e-26 93.4 0.0 1.9e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAN11191.1 - 0.00064 19.3 0.1 0.0013 18.3 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 GAN11191.1 - 0.11 11.4 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Trypsin_2 PF13365.6 GAN11192.1 - 3.7e-07 31.2 0.0 7.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAN11192.1 - 0.033 14.0 0.5 1.3 8.8 0.1 2.4 2 1 0 2 2 2 0 Trypsin ADH_zinc_N PF00107.26 GAN11194.1 - 7.2e-18 64.8 0.0 2.1e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN11194.1 - 1.2e-05 25.1 0.9 2.2e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.6 GAN11194.1 - 0.044 14.3 0.0 0.33 11.5 0.0 2.2 1 1 0 1 1 1 0 CoA binding domain SplA PF11132.8 GAN11194.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) Lon_C PF05362.13 GAN11195.1 - 6.6e-72 241.4 0.3 1.3e-71 240.4 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 GAN11195.1 - 1.7e-22 80.3 0.0 3.5e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 GAN11195.1 - 4.3e-16 59.4 0.0 8.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 GAN11195.1 - 1.3e-08 34.7 0.0 2.8e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 GAN11195.1 - 1.3e-07 31.7 0.0 4e-07 30.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAN11195.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAN11195.1 - 0.00022 21.5 0.1 0.0099 16.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAN11195.1 - 0.00047 20.3 0.0 0.0015 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAN11195.1 - 0.00062 20.2 0.0 0.0024 18.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 GAN11195.1 - 0.0007 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.6 GAN11195.1 - 0.0019 18.8 0.1 0.0057 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 GAN11195.1 - 0.0019 18.0 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAN11195.1 - 0.0024 17.8 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 GAN11195.1 - 0.004 17.5 0.0 0.016 15.6 0.0 2.1 1 0 0 1 1 1 1 RNA helicase DUF3445 PF11927.8 GAN11195.1 - 0.0043 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NB-ARC PF00931.22 GAN11195.1 - 0.0083 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.17 GAN11195.1 - 0.015 15.1 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 GAN11195.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 GAN11195.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.7 1 1 0 1 1 1 0 NTPase AAA_14 PF13173.6 GAN11195.1 - 0.023 14.7 0.0 0.19 11.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAN11195.1 - 0.026 14.7 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAN11195.1 - 0.11 13.0 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 GAN11195.1 - 0.12 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 GAN11195.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.6 GAN11195.1 - 0.18 12.0 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 GAN11196.1 - 0.00036 20.4 0.1 0.001 18.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like Ribosomal_60s PF00428.19 GAN11196.1 - 0.099 13.2 3.6 0.74 10.4 1.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Q_salvage PF10343.9 GAN11197.1 - 3.9e-119 397.4 0.1 4.6e-119 397.2 0.1 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Nbl1_Borealin_N PF10444.9 GAN11197.1 - 0.09 12.4 2.5 0.27 10.9 0.1 2.7 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal ORC3_N PF07034.11 GAN11198.1 - 1.6e-58 198.4 3.9 3.6e-58 197.2 1.7 2.5 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 GAN11198.1 - 4.6e-34 117.5 1.3 1.1e-20 74.1 0.1 4.2 4 1 1 5 5 5 2 Origin recognition complex winged helix C-terminal PRESAN PF09687.10 GAN11198.1 - 1.1 9.9 5.0 0.83 10.2 0.4 2.8 3 0 0 3 3 3 0 Plasmodium RESA N-terminal Img2 PF05046.14 GAN11199.1 - 5.5e-27 93.9 0.1 6.6e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 GAN11199.1 - 0.0051 17.3 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pho88 PF10032.9 GAN11200.1 - 2.1e-53 180.3 0.0 2.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Striatin PF08232.12 GAN11201.1 - 4.2e-43 147.6 0.3 4.2e-43 147.6 0.3 2.5 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 GAN11201.1 - 8.2e-41 137.2 21.9 5.8e-07 30.1 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN11201.1 - 2.5e-14 53.3 0.2 0.00036 20.8 0.0 5.2 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN11201.1 - 0.0001 21.1 6.1 0.3 9.7 0.3 4.6 2 2 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAN11201.1 - 0.0022 16.8 15.3 0.079 11.7 0.1 3.9 3 2 1 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.6 GAN11201.1 - 0.015 14.8 0.1 0.12 12.0 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain CDC37_N PF03234.14 GAN11201.1 - 1.8 9.5 6.5 4.8 8.1 1.9 2.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DNA_binding_1 PF01035.20 GAN11202.1 - 1.1e-23 83.1 0.0 1.6e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ribosomal_L19 PF01245.20 GAN11203.1 - 7.1e-20 71.0 0.1 1.2e-19 70.3 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L19 Peptidase_M28 PF04389.17 GAN11204.1 - 1.2e-43 149.1 0.1 2e-43 148.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 GAN11204.1 - 5.3e-05 22.4 0.1 0.0019 17.3 0.0 2.8 3 1 1 4 4 4 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 GAN11204.1 - 0.0039 16.9 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LolB PF03550.14 GAN11204.1 - 0.028 14.5 0.1 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB DUF5591 PF17884.1 GAN11204.1 - 0.049 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) MRG PF05712.13 GAN11205.1 - 4.4e-45 153.4 5.0 1.1e-44 152.2 5.0 1.6 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 GAN11205.1 - 3.6e-11 42.8 2.5 7.9e-11 41.7 2.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 GAN11205.1 - 0.022 15.1 0.8 0.077 13.4 0.6 2.0 2 0 0 2 2 2 0 PWWP domain RTP1_C2 PF10304.9 GAN11205.1 - 0.028 14.1 0.1 0.55 10.0 0.0 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Chromo PF00385.24 GAN11205.1 - 0.062 13.2 5.3 0.2 11.6 5.3 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Thiolase_N PF00108.23 GAN11206.1 - 4.8e-29 101.5 2.4 5.3e-29 101.4 2.4 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Mito_morph_reg PF14972.6 GAN11206.1 - 0.058 13.0 0.1 0.09 12.4 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial morphogenesis regulator Gti1_Pac2 PF09729.9 GAN11209.1 - 2.1e-55 187.6 1.3 2.1e-55 187.6 1.3 4.5 2 2 0 2 2 2 1 Gti1/Pac2 family XRCC4 PF06632.12 GAN11209.1 - 0.3 9.9 2.9 0.74 8.6 2.9 1.6 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 zf-C2H2 PF00096.26 GAN11210.1 - 3.6e-05 24.0 17.0 0.0018 18.6 0.4 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN11210.1 - 0.0002 21.9 17.3 0.19 12.6 0.9 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAN11210.1 - 0.00084 19.5 13.0 0.045 13.9 0.3 2.7 2 1 1 3 3 3 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 GAN11210.1 - 0.15 12.5 14.4 0.32 11.5 1.3 3.7 3 1 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 GAN11210.1 - 0.51 8.8 7.9 0.17 10.4 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF629) GPI-anchored PF10342.9 GAN11211.1 - 2.6e-11 44.1 0.1 2.6e-11 44.1 0.1 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 GAN11211.1 - 3.6 6.7 15.0 4.4 6.4 15.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ParA PF10609.9 GAN11213.1 - 5.9e-100 333.8 0.0 6.9e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAN11213.1 - 8.3e-09 35.6 0.0 2.3e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAN11213.1 - 1.8e-05 24.7 0.0 7.4e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAN11213.1 - 8.6e-05 21.9 0.1 0.00056 19.2 0.0 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 GAN11213.1 - 0.0028 17.5 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 GAN11213.1 - 0.0062 16.0 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 GAN11213.1 - 0.0071 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAN11213.1 - 0.0099 15.8 0.0 0.021 14.7 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase TF_Zn_Ribbon PF08271.12 GAN11213.1 - 0.032 13.7 0.5 0.078 12.5 0.1 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding CBP_BcsQ PF06564.12 GAN11213.1 - 0.035 13.6 0.1 0.17 11.3 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 GAN11213.1 - 0.04 13.2 0.1 0.087 12.1 0.1 1.6 1 1 0 1 1 1 0 ATPase MipZ AAA_16 PF13191.6 GAN11213.1 - 0.047 14.1 0.1 0.078 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 GAN11213.1 - 0.21 11.6 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SNARE PF05739.19 GAN11214.1 - 2.8e-06 27.2 1.0 2.8e-06 27.2 1.0 2.5 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 GAN11214.1 - 0.0064 16.2 9.2 0.021 14.6 8.6 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 TBCA PF02970.16 GAN11214.1 - 0.82 10.0 11.6 0.066 13.5 1.7 2.9 2 2 0 2 2 2 0 Tubulin binding cofactor A FUSC-like PF12805.7 GAN11214.1 - 1.1 8.3 4.6 0.21 10.6 0.4 1.9 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS FemAB PF02388.16 GAN11214.1 - 2 7.2 7.1 2.5 6.9 3.2 2.0 2 0 0 2 2 2 0 FemAB family NBP1 PF08537.10 GAN11214.1 - 3.8 6.8 14.7 0.25 10.7 4.0 2.5 2 1 0 2 2 2 0 Fungal Nap binding protein NBP1 CAF1A PF12253.8 GAN11215.1 - 0.03 14.5 4.3 0.059 13.5 3.0 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Pkinase PF00069.25 GAN11216.1 - 2.9e-72 243.2 0.0 3.9e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11216.1 - 7.7e-34 117.1 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAN11216.1 - 5.5e-11 43.0 5.6 5.5e-11 43.0 5.6 2.2 2 1 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAN11216.1 - 4.8e-08 32.3 0.0 8.3e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAN11216.1 - 3.7e-05 23.2 0.0 0.00016 21.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAN11216.1 - 0.11 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAN11216.1 - 0.16 11.3 0.1 0.33 10.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP_N PF17093.5 GAN11216.1 - 6.3 7.1 10.6 0.9 9.8 6.1 1.9 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Hemerythrin PF01814.23 GAN11217.1 - 5.1e-12 46.5 1.3 6.9e-12 46.1 1.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DNA_ligase_A_M PF01068.21 GAN11218.1 - 1.4e-40 139.1 0.2 4.2e-40 137.6 0.1 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAN11218.1 - 4.8e-33 114.9 0.7 1e-32 113.8 0.7 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 GAN11218.1 - 1.3e-12 48.3 0.1 3e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 GAN11218.1 - 5.4e-12 46.0 0.0 1.8e-07 31.5 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 GAN11218.1 - 2.7e-09 37.5 0.0 8.9e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 GAN11218.1 - 0.00042 20.2 0.2 0.035 13.9 0.2 2.5 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DSPc PF00782.20 GAN11219.1 - 1.5e-26 92.8 1.8 1.1e-20 73.7 0.4 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAN11219.1 - 1.1e-05 25.1 0.1 2.3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 GAN11219.1 - 0.012 15.9 0.1 0.064 13.6 0.0 2.2 2 0 0 2 2 2 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 GAN11219.1 - 0.056 13.5 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3644 PF12358.8 GAN11219.1 - 0.11 13.0 0.1 0.87 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) Stm1_N PF09598.10 GAN11220.1 - 0.0014 19.4 1.6 0.0014 19.4 1.6 3.7 3 1 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 GAN11220.1 - 0.0076 17.1 16.5 0.0076 17.1 16.5 3.9 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family TMEM237 PF15383.6 GAN11220.1 - 0.3 10.2 0.3 0.38 9.8 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Reticulon PF02453.17 GAN11221.1 - 2.7e-24 85.9 2.6 3.7e-24 85.5 2.6 1.2 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 GAN11221.1 - 0.05 13.0 1.3 0.22 10.9 0.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) ParBc PF02195.18 GAN11222.1 - 2.1e-11 44.0 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain Lipase_GDSL PF00657.22 GAN11223.1 - 3.4e-09 37.0 0.0 6.5e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN11223.1 - 4.9e-07 30.3 0.6 1.1e-05 26.0 0.6 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ACOX PF01756.19 GAN11224.1 - 1.7e-35 122.2 0.0 3.7e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAN11224.1 - 1.3e-14 54.8 0.1 3.1e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAN11224.1 - 3.3e-14 52.9 0.1 8.8e-14 51.5 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAN11224.1 - 0.083 13.1 0.3 0.28 11.4 0.3 1.9 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain CRIM PF16978.5 GAN11225.1 - 1.5e-41 141.8 0.1 9.9e-41 139.2 0.0 2.3 2 1 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 GAN11225.1 - 2.6e-25 88.8 0.4 6.2e-25 87.6 0.4 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 GAN11225.1 - 0.057 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain Ldt_C PF17969.1 GAN11225.1 - 0.88 10.4 4.0 6.3 7.6 2.0 2.9 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain SLC35F PF06027.12 GAN11226.1 - 8.2e-97 324.3 24.8 9.7e-97 324.1 24.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 GAN11226.1 - 2.1e-09 36.8 6.8 2.1e-09 36.8 6.8 1.9 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAN11226.1 - 5.3e-09 36.4 30.5 9.3e-05 22.6 10.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family UPF0139 PF03669.13 GAN11226.1 - 2.7 7.9 4.8 0.71 9.8 1.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Sec62 PF03839.16 GAN11226.1 - 4 6.9 8.0 11 5.5 8.0 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 TBP PF00352.21 GAN11227.1 - 3.3e-68 225.6 0.1 1.8e-33 114.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 GAN11227.1 - 3e-05 24.1 0.0 0.22 11.7 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 GAN11227.1 - 0.056 13.3 0.1 0.23 11.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Y_phosphatase PF00102.27 GAN11229.1 - 2e-51 174.9 0.0 4.8e-47 160.5 0.0 2.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 GAN11229.1 - 5.2e-13 49.4 0.0 9.2e-12 45.4 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 GAN11229.1 - 0.037 13.8 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Glyco_tranf_2_4 PF13704.6 GAN11229.1 - 0.14 12.7 0.0 0.97 10.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 NmrA PF05368.13 GAN11230.1 - 2.7e-06 27.1 0.0 4.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAN11230.1 - 3.9e-06 26.9 0.0 9.2e-06 25.7 0.0 1.5 1 1 1 2 2 2 1 NAD(P)H-binding Pro_sub2 PF18513.1 GAN11230.1 - 0.0021 18.2 0.5 0.007 16.5 0.1 2.1 2 0 0 2 2 2 1 Prodomain subtilisin 2 Flavodoxin_1 PF00258.25 GAN11230.1 - 0.088 13.0 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin ClpB_D2-small PF10431.9 GAN11230.1 - 0.15 12.1 0.2 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Rad60-SLD PF11976.8 GAN11231.1 - 5.1e-23 80.7 0.0 6.1e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAN11231.1 - 2.1e-10 40.2 0.0 3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family SCO1-SenC PF02630.14 GAN11232.1 - 1.8e-44 150.9 0.0 2.7e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 GAN11232.1 - 0.00012 22.3 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GAN11232.1 - 0.0036 17.2 0.0 0.0074 16.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family AATase PF07247.12 GAN11236.1 - 3.1e-26 92.0 0.0 4.9e-24 84.7 0.0 2.4 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 GAN11236.1 - 4.7e-14 51.9 1.2 1.5e-10 40.4 0.9 2.9 3 0 0 3 3 3 2 Condensation domain Transferase PF02458.15 GAN11236.1 - 0.0063 15.2 0.0 0.49 9.0 0.0 2.2 2 0 0 2 2 2 2 Transferase family Ras PF00071.22 GAN11237.1 - 4.5e-53 179.2 0.0 5.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN11237.1 - 2.1e-19 69.9 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN11237.1 - 4.5e-07 29.5 0.0 6.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAN11237.1 - 0.092 12.3 0.0 0.77 9.3 0.0 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 GAN11238.1 - 4.3e-29 100.1 0.2 4.3e-15 55.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAN11238.1 - 4.2e-06 26.7 0.1 0.00089 19.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif SET PF00856.28 GAN11238.1 - 0.0009 19.7 0.1 0.0067 16.8 0.0 2.3 2 1 0 2 2 2 1 SET domain Limkain-b1 PF11608.8 GAN11238.1 - 0.0014 18.6 2.0 0.18 11.9 0.1 2.5 2 0 0 2 2 2 2 Limkain b1 DbpA PF03880.15 GAN11238.1 - 0.014 15.3 0.2 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_5 PF13893.6 GAN11238.1 - 0.11 12.1 0.0 7.9 6.1 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 GAN11238.1 - 0.17 11.5 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Thioredoxin PF00085.20 GAN11239.1 - 7.8e-63 208.9 0.0 2.5e-31 107.7 0.0 2.5 2 1 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 GAN11239.1 - 2.6e-21 76.3 0.9 4.7e-21 75.5 0.3 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GAN11239.1 - 7.5e-16 58.3 0.0 1.4e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAN11239.1 - 1.1e-10 42.0 0.1 0.00062 20.2 0.0 3.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAN11239.1 - 3.5e-09 36.7 0.0 0.00024 21.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 GAN11239.1 - 6e-08 32.6 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 GAN11239.1 - 4.4e-06 26.9 0.0 0.18 12.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 GAN11239.1 - 0.001 18.8 0.2 0.28 10.9 0.1 2.3 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 GAN11239.1 - 0.0041 17.1 0.0 0.42 10.6 0.0 2.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 GAN11239.1 - 0.012 15.4 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein NTF2 PF02136.20 GAN11240.1 - 1e-35 122.9 0.2 1.1e-35 122.8 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 GAN11240.1 - 0.026 14.4 0.0 0.04 13.9 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 CYSTM PF12734.7 GAN11241.1 - 2.7e-07 30.8 10.6 3.3e-07 30.5 8.7 1.9 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance DUF3087 PF11286.8 GAN11242.1 - 0.01 15.3 0.2 0.023 14.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) AA_permease_2 PF13520.6 GAN11242.1 - 7.8 5.2 26.4 0.016 14.0 15.7 1.9 2 1 0 2 2 2 0 Amino acid permease SDP_N PF12278.8 GAN11244.1 - 3 8.0 5.0 7.5 6.7 5.0 1.6 1 0 0 1 1 1 0 Sex determination protein N terminal ADH_zinc_N PF00107.26 GAN11246.1 - 1.6e-22 79.9 0.2 2.8e-22 79.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAN11246.1 - 1.5e-09 39.0 0.0 2.9e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAN11246.1 - 3.3e-06 27.0 0.1 1e-05 25.3 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAN11246.1 - 0.015 14.6 0.7 0.023 14.0 0.2 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III_C PF08541.10 GAN11246.1 - 0.039 14.1 0.2 0.18 12.0 0.1 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Pyr_redox_2 PF07992.14 GAN11247.1 - 9e-32 110.5 0.1 1.6e-31 109.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAN11247.1 - 3.3e-17 62.8 0.0 1.7e-11 44.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 GAN11247.1 - 8.6e-10 38.9 0.1 1.9e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.24 GAN11247.1 - 6.1e-09 35.9 0.0 0.026 14.1 0.0 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN11247.1 - 4.7e-07 29.9 0.0 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAN11247.1 - 1.6e-06 27.6 0.0 1.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAN11247.1 - 3.6e-05 23.8 0.2 9 6.3 0.0 4.5 2 2 2 4 4 4 1 FAD-NAD(P)-binding RGS-like PF09128.11 GAN11247.1 - 0.0006 19.6 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain FAD_binding_3 PF01494.19 GAN11247.1 - 0.00095 18.5 0.0 0.92 8.7 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.18 GAN11247.1 - 0.001 19.3 0.1 0.43 10.9 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 GAN11247.1 - 0.0013 17.9 0.0 0.68 8.9 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 GAN11247.1 - 0.0072 16.6 0.4 7.5 6.8 0.0 3.1 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 GAN11247.1 - 0.0083 15.3 0.0 1.1 8.3 0.0 2.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 GAN11247.1 - 0.01 15.4 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Trp_halogenase PF04820.14 GAN11247.1 - 0.025 13.4 0.0 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 GAN11247.1 - 0.04 13.2 0.0 10 5.4 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAN11247.1 - 0.063 12.4 0.2 6.2 5.8 0.0 3.4 4 0 0 4 4 4 0 Glucose inhibited division protein A zf-CCHC PF00098.23 GAN11248.1 - 5e-05 23.2 14.9 0.0036 17.3 2.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 GAN11248.1 - 1.5 8.6 7.5 0.31 10.8 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 GAN11248.1 - 3.2 7.6 10.5 0.38 10.5 3.1 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger RNB PF00773.19 GAN11249.1 - 1.4e-79 267.8 0.5 2.9e-79 266.7 0.1 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 GAN11249.1 - 2.3e-18 66.0 0.0 5.4e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) OB_RNB PF08206.11 GAN11249.1 - 0.017 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Torus PF16131.5 GAN11250.1 - 1.3e-05 25.8 0.2 2.5e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 GAN11250.1 - 1.5e-05 24.9 6.9 2.4e-05 24.2 6.9 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAN11250.1 - 0.00023 21.0 3.2 0.00036 20.4 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAN11250.1 - 0.0053 16.5 5.0 0.0095 15.7 5.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAN11250.1 - 0.086 13.3 4.8 0.2 12.2 4.8 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger VAR1 PF05316.12 GAN11251.1 - 2.5e-07 30.1 3.5 0.0002 20.5 0.2 3.3 2 2 1 3 3 3 2 Mitochondrial ribosomal protein (VAR1) Ribosomal_S3_C PF00189.20 GAN11251.1 - 7.6e-07 29.6 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain APG9 PF04109.16 GAN11252.1 - 1.4e-208 693.8 13.5 1.6e-208 693.6 13.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 MG2 PF01835.19 GAN11253.1 - 0.0025 18.2 0.0 0.0034 17.8 0.0 1.2 1 0 0 1 1 1 1 MG2 domain Glyco_hydro_61 PF03443.14 GAN11253.1 - 0.032 14.2 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF5103 PF17116.5 GAN11253.1 - 0.048 12.9 0.1 0.058 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) 6PF2K PF01591.18 GAN11257.1 - 6.4e-80 267.6 0.1 8.9e-80 267.2 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAN11257.1 - 8.1e-35 120.3 0.0 1.7e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAN11257.1 - 9.2e-05 22.6 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain BCDHK_Adom3 PF10436.9 GAN11258.1 - 3.6e-44 150.4 2.9 5.6e-44 149.8 2.7 1.4 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAN11258.1 - 2.9e-11 43.9 0.0 5.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAN11258.1 - 0.1 12.5 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAN11258.1 - 0.18 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MRAP PF15183.6 GAN11259.1 - 0.009 15.9 3.5 0.022 14.7 0.0 2.8 2 1 0 2 2 2 1 Melanocortin-2 receptor accessory protein family Shisa PF13908.6 GAN11259.1 - 0.16 12.2 1.3 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Thiolase_N PF00108.23 GAN11260.1 - 8.7e-52 176.0 0.0 2e-51 174.9 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAN11260.1 - 1e-43 147.9 0.5 1.6e-43 147.2 0.5 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain PilJ_C PF18223.1 GAN11261.1 - 0.089 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Pili PilJ C-terminal domain DUF4423 PF14394.6 GAN11262.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) SirB PF04247.12 GAN11263.1 - 0.014 15.4 1.4 0.023 14.8 1.4 1.2 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF2207 PF09972.9 GAN11263.1 - 0.056 12.2 0.1 0.071 11.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4051 PF13260.6 GAN11263.1 - 0.79 9.5 2.6 0.41 10.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) MRP-L28 PF09812.9 GAN11264.1 - 1.5e-17 64.2 1.4 1.7e-17 64.1 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF241 PF03087.14 GAN11264.1 - 0.0049 16.7 0.7 0.0058 16.5 0.7 1.0 1 0 0 1 1 1 1 Arabidopsis protein of unknown function FliD_N PF02465.18 GAN11264.1 - 0.17 12.6 1.2 2.1 9.1 0.2 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Zip PF02535.22 GAN11266.1 - 3.1e-30 105.5 6.0 3.1e-30 105.5 6.0 1.7 1 1 1 2 2 2 1 ZIP Zinc transporter SUIM_assoc PF16619.5 GAN11266.1 - 0.022 14.8 0.8 0.022 14.8 0.8 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4203 PF13886.6 GAN11266.1 - 0.12 12.0 14.5 0.19 11.4 4.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4203) DUF2700 PF10912.8 GAN11266.1 - 0.51 10.4 4.4 0.88 9.6 0.5 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2700) Transcrip_reg PF01709.20 GAN11267.1 - 1e-78 264.1 5.1 1.2e-78 263.9 5.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator HTH_15 PF12324.8 GAN11267.1 - 0.039 13.9 0.1 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase CENP-K PF11802.8 GAN11267.1 - 0.047 13.3 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Chal_sti_synt_C PF02797.15 GAN11267.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain CDH1_2_SANT_HL1 PF18375.1 GAN11267.1 - 0.36 11.5 0.1 0.36 11.5 0.1 2.3 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Ribonuc_2-5A PF06479.12 GAN11268.1 - 4.8e-44 149.6 0.0 1e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 GAN11268.1 - 1.1e-41 143.0 0.0 5.4e-40 137.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11268.1 - 2.3e-24 86.1 0.0 2.1e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAN11268.1 - 5.3e-05 22.2 0.8 0.0037 16.1 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase PQQ_2 PF13360.6 GAN11268.1 - 0.0035 17.0 0.0 0.41 10.2 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 GAN11268.1 - 0.049 13.6 1.3 1.2 9.2 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat DUF2072 PF09845.9 GAN11268.1 - 3.9 7.7 6.7 8.4 6.7 6.7 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein PQQ_3 PF13570.6 GAN11268.1 - 9 6.9 8.2 23 5.6 0.4 4.1 3 1 0 3 3 3 0 PQQ-like domain CotH PF08757.11 GAN11269.1 - 2.6e-40 138.9 1.3 3.5e-40 138.5 1.3 1.2 1 0 0 1 1 1 1 CotH kinase protein EphA2_TM PF14575.6 GAN11270.1 - 0.029 15.3 0.6 0.14 13.0 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 GAN11270.1 - 0.032 14.0 0.6 0.046 13.5 0.6 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ECSCR PF15820.5 GAN11270.1 - 0.31 10.9 0.1 0.31 10.9 0.1 3.8 4 2 1 5 5 5 0 Endothelial cell-specific chemotaxis regulator Gram_pos_anchor PF00746.21 GAN11270.1 - 3.5 7.7 6.0 0.71 9.9 0.6 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Put_Phosphatase PF06888.12 GAN11272.1 - 6.2e-44 150.1 0.2 7.4e-44 149.9 0.2 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 GAN11272.1 - 3.9e-06 27.4 0.2 0.00012 22.6 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN11272.1 - 0.0086 16.4 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 GAN11272.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) HhH-GPD PF00730.25 GAN11273.1 - 2e-21 76.5 0.0 4.7e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAN11273.1 - 2.8e-07 30.1 0.0 6.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 GAN11273.1 - 0.013 15.8 5.2 0.028 14.8 5.2 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DUF2400 PF09674.10 GAN11273.1 - 0.049 13.6 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) AtuA PF07287.11 GAN11274.1 - 9.9e-33 113.3 0.0 1.1e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA p450 PF00067.22 GAN11277.1 - 3.1e-99 332.8 0.1 6e-99 331.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_1 PF00667.20 GAN11277.1 - 1.2e-31 110.0 0.0 7.2e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 GAN11277.1 - 5.4e-24 85.0 0.4 1.2e-23 83.9 0.4 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAN11277.1 - 7.2e-16 58.8 0.0 1.7e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAN11277.1 - 0.043 13.9 0.0 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 Ferric reductase NAD binding domain UNC45-central PF11701.8 GAN11277.1 - 0.088 12.8 0.0 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DDE_3 PF13358.6 GAN11278.1 - 1.9e-25 89.3 0.0 4.9e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease PPR_2 PF13041.6 GAN11279.1 - 3.2e-59 196.9 27.9 5.4e-13 48.9 0.1 12.5 7 5 6 13 13 12 10 PPR repeat family PPR_3 PF13812.6 GAN11279.1 - 5.5e-46 154.5 14.9 1.7e-10 40.8 0.2 9.6 6 3 3 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 GAN11279.1 - 6.6e-40 132.6 17.8 0.00074 19.6 0.1 14.1 15 0 0 15 15 15 8 PPR repeat PPR_1 PF12854.7 GAN11279.1 - 9.2e-34 114.8 17.1 1.8e-05 24.3 0.0 13.1 14 0 0 14 14 14 6 PPR repeat PPR_long PF17177.4 GAN11279.1 - 4.4e-26 91.6 9.8 1.5e-08 34.2 0.1 6.2 1 1 5 6 6 6 6 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GAN11279.1 - 8.7e-06 26.2 3.3 0.98 10.0 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAN11279.1 - 0.0032 17.4 1.6 0.3 11.0 0.0 3.3 3 0 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal MRP-S27 PF10037.9 GAN11279.1 - 0.011 14.6 2.4 1.7 7.4 0.1 3.9 4 0 0 4 4 4 0 Mitochondrial 28S ribosomal protein S27 Gal11_ABD1 PF18535.1 GAN11279.1 - 0.069 13.2 0.0 5.6 7.1 0.0 3.1 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) CHAD PF05235.14 GAN11279.1 - 0.092 12.7 0.0 0.83 9.6 0.0 2.5 3 0 0 3 3 3 0 CHAD domain BTAD PF03704.17 GAN11279.1 - 0.34 11.3 3.1 20 5.6 0.1 4.1 4 0 0 4 4 4 0 Bacterial transcriptional activator domain RPM2 PF08579.11 GAN11279.1 - 3.6 8.0 14.7 14 6.1 0.0 6.7 5 1 3 8 8 8 0 Mitochondrial ribonuclease P subunit (RPM2) N6_Mtase PF02384.16 GAN11280.1 - 3.9e-18 65.8 0.0 4.1e-15 55.8 0.0 3.3 2 1 0 2 2 2 1 N-6 DNA Methylase Eco57I PF07669.11 GAN11280.1 - 3e-07 30.9 0.0 1e-06 29.2 0.0 2.0 1 0 0 1 1 1 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 GAN11280.1 - 0.00021 21.3 0.0 0.00071 19.6 0.0 1.8 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain MTS PF05175.14 GAN11280.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain SPRY PF00622.28 GAN11281.1 - 1.5e-17 63.8 0.1 3.1e-17 62.8 0.1 1.5 2 0 0 2 2 2 1 SPRY domain Neuralized PF07177.12 GAN11281.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Neuralized TPT PF03151.16 GAN11282.1 - 2.3e-45 155.2 27.7 2.8e-45 154.9 27.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAN11282.1 - 3e-12 46.4 28.5 3.9e-12 46.0 28.5 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAN11282.1 - 1.6e-08 34.8 33.4 9.9e-05 22.5 13.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAN11282.1 - 0.0034 16.6 11.6 0.0084 15.3 2.4 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter Phage_holin_3_2 PF04550.12 GAN11282.1 - 2.1 8.9 6.4 18 5.9 0.1 3.2 3 1 1 4 4 4 0 Phage holin family 2 Vac14_Fab1_bd PF12755.7 GAN11283.1 - 0.00024 21.6 0.1 0.12 13.0 0.0 2.1 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 GAN11283.1 - 0.0028 17.7 1.1 0.005 16.9 0.4 1.6 1 1 1 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 GAN11283.1 - 0.0047 17.3 0.0 0.0069 16.8 0.0 1.3 1 0 0 1 1 1 1 HEAT repeats Cnd3 PF12719.7 GAN11283.1 - 0.034 13.3 0.2 0.044 13.0 0.2 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 GAN11283.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 HEAT repeat Cnd1 PF12717.7 GAN11283.1 - 0.069 13.2 1.8 0.14 12.2 1.8 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF1462 PF07315.11 GAN11283.1 - 0.14 12.5 0.1 0.24 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1462) Beta-Casp PF10996.8 GAN11284.1 - 7.3e-27 93.8 0.0 2.7e-25 88.8 0.0 2.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 GAN11284.1 - 2.9e-22 79.1 0.0 5.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 GAN11284.1 - 2.2e-17 62.7 0.0 4.4e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 GAN11284.1 - 1.1e-11 45.1 0.0 1.9e-10 41.1 0.1 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAN11284.1 - 3.3e-11 43.1 0.2 6.7e-10 38.8 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAN11284.1 - 0.00011 22.1 0.0 0.00066 19.6 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain FCH PF00611.23 GAN11285.1 - 5e-08 33.1 1.2 1.5e-07 31.6 0.2 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Sulfotransfer_4 PF17784.1 GAN11286.1 - 6.3e-61 205.9 0.1 7.2e-61 205.7 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAN11286.1 - 0.02 15.3 0.4 0.16 12.3 0.1 2.0 1 1 1 2 2 2 0 Sulfotransferase family Tricorn_C1 PF14684.6 GAN11286.1 - 1.3 9.1 4.9 1.7 8.8 2.7 2.3 3 0 0 3 3 3 0 Tricorn protease C1 domain RTP1_C1 PF10363.9 GAN11288.1 - 7.1e-33 113.1 0.1 2.9e-32 111.2 0.1 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 GAN11288.1 - 1.4e-11 43.8 1.7 4.8e-11 42.1 1.7 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 GAN11288.1 - 1.2e-05 25.6 4.8 0.16 12.3 0.0 5.1 5 1 0 5 5 5 2 HEAT repeats RIX1 PF08167.12 GAN11288.1 - 0.0062 16.3 3.3 0.037 13.8 0.3 3.3 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis MMS19_N PF14500.6 GAN11288.1 - 0.034 13.7 0.9 0.17 11.4 0.0 2.8 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 GAN11288.1 - 0.11 13.1 0.2 14 6.4 0.0 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Actin PF00022.19 GAN11289.1 - 1.7e-85 287.1 0.0 1.7e-84 283.8 0.0 1.9 1 1 0 1 1 1 1 Actin Acyltransferase PF01553.21 GAN11290.1 - 3.3e-10 39.7 0.0 6.2e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Chitin_synth_1 PF01644.17 GAN11292.1 - 2.8e-78 261.5 0.3 4.4e-78 260.9 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAN11292.1 - 4.5e-28 97.0 0.1 1.2e-27 95.7 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAN11292.1 - 8.3e-19 67.6 0.0 9e-18 64.2 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAN11292.1 - 3.2e-06 27.2 0.1 1e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Arm PF00514.23 GAN11293.1 - 2e-09 37.2 9.2 0.045 13.8 0.0 9.0 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat KAP PF05804.12 GAN11293.1 - 1.9e-06 26.4 7.8 5.3e-05 21.6 0.1 2.6 1 1 0 2 2 2 2 Kinesin-associated protein (KAP) UNC45-central PF11701.8 GAN11293.1 - 0.041 13.8 4.1 1.1 9.3 0.7 4.2 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central Terminase_3C PF17288.2 GAN11293.1 - 0.057 13.8 0.9 0.72 10.2 0.9 2.6 1 1 0 1 1 1 0 Terminase RNAseH like domain Atx10homo_assoc PF09759.9 GAN11293.1 - 0.07 13.2 7.1 3.2 7.8 0.0 4.5 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 GAN11293.1 - 0.16 12.3 0.4 4.6 7.8 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Sigma70_r1_1 PF03979.14 GAN11293.1 - 0.65 10.1 9.4 0.048 13.7 3.1 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 SAPS PF04499.15 GAN11294.1 - 3.9 6.1 10.3 5.1 5.8 10.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SNARE_assoc PF09335.11 GAN11297.1 - 1.6e-17 64.1 7.3 1.6e-17 64.1 7.3 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4293 PF14126.6 GAN11297.1 - 0.08 13.2 2.2 7.4 6.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF3656 PF12392.8 GAN11297.1 - 0.14 12.8 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Collagenase p450 PF00067.22 GAN11298.1 - 8.8e-86 288.5 0.0 1.2e-85 288.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S10 PF00338.22 GAN11298.1 - 1.3e-27 95.8 0.5 3.4e-27 94.6 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF5087 PF17006.5 GAN11298.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) DUF1640 PF07798.11 GAN11299.1 - 0.00047 20.2 1.7 0.00066 19.8 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ATG16 PF08614.11 GAN11299.1 - 0.012 15.8 2.1 0.016 15.4 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 GAN11299.1 - 0.14 12.2 0.8 0.41 10.7 0.6 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLU PF13236.6 GAN11300.1 - 1.4e-83 280.1 0.0 3.4e-83 278.8 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAN11300.1 - 5.5e-50 169.8 0.2 1.4e-49 168.5 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_10 PF13374.6 GAN11300.1 - 1.3e-20 72.6 0.5 2.8e-06 27.0 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAN11300.1 - 4.8e-20 71.6 6.7 2.3e-09 37.4 0.0 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.6 GAN11300.1 - 3.9e-19 68.8 0.2 3.1e-18 65.9 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 GAN11300.1 - 7.7e-08 32.4 0.4 2.7e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 GAN11300.1 - 0.055 13.7 1.7 4.1 7.9 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN11300.1 - 0.062 13.4 8.7 18 5.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAN11300.1 - 0.27 11.4 2.4 9.6 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SET PF00856.28 GAN11301.1 - 7.7e-11 42.7 0.2 5.7e-10 39.8 0.2 2.2 1 1 0 1 1 1 1 SET domain I-set PF07679.16 GAN11302.1 - 9.4e-06 25.6 0.0 3.6 7.7 0.1 4.9 4 0 0 4 4 4 3 Immunoglobulin I-set domain DNase_II PF03265.15 GAN11303.1 - 0.0075 15.6 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Deoxyribonuclease II G-patch PF01585.23 GAN11304.1 - 6.9e-14 51.5 1.4 1.4e-13 50.5 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAN11304.1 - 0.016 15.3 0.2 0.016 15.3 0.2 2.5 3 0 0 3 3 3 0 G-patch domain G2BR PF18442.1 GAN11304.1 - 0.038 13.6 0.6 0.08 12.6 0.6 1.5 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) GATA PF00320.27 GAN11305.1 - 1.2e-15 56.8 3.2 1.2e-15 56.8 3.2 2.0 2 0 0 2 2 2 1 GATA zinc finger Rox3 PF08633.10 GAN11305.1 - 4 7.7 12.9 0.13 12.6 2.4 2.3 1 1 1 2 2 2 0 Rox3 mediator complex subunit SCA7 PF08313.12 GAN11306.1 - 5.1e-27 93.6 0.5 5.1e-27 93.6 0.5 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain HAMP PF00672.25 GAN11307.1 - 6.1e-69 228.3 19.1 5.6e-08 33.1 0.2 10.5 9 0 0 9 9 9 9 HAMP domain HTH_6 PF01418.17 GAN11307.1 - 1.4e-06 28.2 0.5 14 5.7 0.0 6.8 7 0 0 7 7 7 1 Helix-turn-helix domain, rpiR family SpoIIID PF12116.8 GAN11307.1 - 0.00012 22.1 15.8 19 5.5 0.0 7.7 7 0 0 7 7 7 0 Stage III sporulation protein D GatB_Yqey PF02637.18 GAN11307.1 - 0.00026 20.9 21.7 1.4 8.8 0.1 7.6 7 1 1 8 8 8 2 GatB domain HMG_box PF00505.19 GAN11307.1 - 0.0092 16.4 0.0 26 5.3 0.0 4.1 4 0 0 4 4 4 0 HMG (high mobility group) box WXG100 PF06013.12 GAN11307.1 - 0.017 15.3 25.4 20 5.5 0.1 8.8 9 0 0 9 9 9 0 Proteins of 100 residues with WXG ImcF-related_N PF14331.6 GAN11307.1 - 0.093 12.1 0.1 42 3.4 0.0 4.1 5 0 0 5 5 5 0 ImcF-related N-terminal domain Vac_Fusion PF02346.16 GAN11307.1 - 2 8.1 5.0 1.2e+02 2.4 0.1 5.3 5 0 0 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 DUF1759 PF03564.15 GAN11307.1 - 3.6 7.5 17.0 18 5.2 0.0 6.8 7 1 1 8 8 8 0 Protein of unknown function (DUF1759) Glutenin_hmw PF03157.13 GAN11307.1 - 3.9 5.8 5.1 17 3.7 0.1 3.6 4 0 0 4 4 4 0 High molecular weight glutenin subunit AA_permease_2 PF13520.6 GAN11308.1 - 9.2e-40 136.7 62.9 3.3e-25 88.8 21.0 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 GAN11308.1 - 3.3e-08 32.6 60.2 6e-06 25.1 22.0 2.1 1 1 1 2 2 2 2 Amino acid permease Kelch_5 PF13854.6 GAN11309.1 - 1.1e-09 38.1 8.4 0.16 12.0 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 GAN11309.1 - 3.1e-07 30.3 16.0 0.0032 17.4 0.0 6.5 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAN11309.1 - 0.00057 19.8 3.4 27 5.0 0.0 5.5 6 0 0 6 6 6 0 Kelch motif SKG6 PF08693.10 GAN11309.1 - 0.00088 18.6 0.2 0.002 17.5 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.25 GAN11309.1 - 0.0011 18.5 0.0 0.036 13.6 0.1 3.1 3 0 0 3 3 3 1 Kelch motif MGC-24 PF05283.11 GAN11309.1 - 0.015 15.7 2.3 0.27 11.7 0.0 3.2 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTP_tm PF18861.1 GAN11309.1 - 0.07 13.1 0.1 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J FAA_hydrolase PF01557.18 GAN11311.1 - 1.3e-38 132.8 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAN11311.1 - 2.1e-37 127.6 0.0 5.8e-37 126.1 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.16 GAN11312.1 - 2.1e-62 211.1 37.9 1.6e-55 188.5 24.1 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN11312.1 - 1.9e-16 60.0 18.0 2.1e-12 46.7 8.7 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 GAN11312.1 - 3.9e-07 28.8 10.8 6.9e-05 21.3 5.9 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAN11312.1 - 0.31 9.8 22.5 0.22 10.4 1.3 3.8 2 1 2 4 4 4 0 MFS_1 like family Myb_DNA-binding PF00249.31 GAN11313.1 - 7.4e-40 134.9 7.7 1.4e-15 57.2 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAN11313.1 - 1.2e-32 111.9 7.6 2.6e-16 59.6 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAN11313.1 - 3.7e-05 23.5 1.7 0.19 11.6 0.0 3.2 3 1 0 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 GAN11313.1 - 0.00064 19.8 0.0 4.6 7.4 0.2 3.4 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 GAN11313.1 - 0.0028 18.0 9.7 2.9 8.3 1.2 4.2 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 GAN11313.1 - 0.0044 17.0 0.1 0.97 9.5 0.0 3.6 2 1 1 3 3 3 1 SLIDE NAD_binding_4 PF07993.12 GAN11314.1 - 4.4e-46 157.2 0.0 7.8e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAN11314.1 - 3.3e-06 26.7 0.0 8.6e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN11314.1 - 9.3e-06 24.8 2.4 0.0001 21.5 0.9 2.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Acyltransferase PF01553.21 GAN11314.1 - 4.9e-05 23.0 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Polysacc_synt_2 PF02719.15 GAN11314.1 - 0.015 14.5 0.0 0.064 12.4 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein CDC45 PF02724.14 GAN11314.1 - 4.1 5.6 8.9 2.2 6.4 1.7 2.3 2 0 0 2 2 2 0 CDC45-like protein Androgen_recep PF02166.16 GAN11314.1 - 5.4 5.8 18.2 13 4.5 18.2 1.5 1 0 0 1 1 1 0 Androgen receptor UvrD_C_2 PF13538.6 GAN11315.1 - 0.11 12.3 0.3 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain CS PF04969.16 GAN11316.1 - 1.5e-06 29.1 0.1 2.5e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 CS domain SRA PF18491.1 GAN11316.1 - 0.062 13.4 2.5 0.088 12.9 1.6 1.6 1 1 1 2 2 2 0 SET and RING associated domain OstA PF03968.14 GAN11316.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 OstA-like protein HMG_box PF00505.19 GAN11317.1 - 1.2e-17 64.1 0.1 3.2e-17 62.7 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAN11317.1 - 2.4e-11 44.1 0.1 8.1e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 HMG-box domain ZapB PF06005.12 GAN11317.1 - 0.018 15.5 1.6 0.018 15.5 1.6 2.8 2 0 0 2 2 2 0 Cell division protein ZapB DUF4756 PF15948.5 GAN11317.1 - 0.07 13.0 3.5 0.13 12.1 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) YABBY PF04690.13 GAN11317.1 - 3.6 8.1 11.8 0.35 11.4 1.6 2.5 2 0 0 2 2 2 0 YABBY protein bZIP_1 PF00170.21 GAN11317.1 - 7.2 6.8 10.2 0.89 9.7 5.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor Glyco_hydro_16 PF00722.21 GAN11318.1 - 1e-28 100.0 1.5 1.3e-28 99.7 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 GAN11319.1 - 4.1e-14 52.3 61.0 2.8e-13 49.5 59.6 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAN11320.1 - 1.8e-11 43.5 25.4 1.8e-10 40.3 25.4 2.3 1 1 0 1 1 1 1 MFS_1 like family Asp PF00026.23 GAN11321.1 - 7.9e-44 150.3 1.2 1.9e-22 80.1 0.1 2.2 1 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAN11321.1 - 3.3e-07 30.7 12.0 1.3e-06 28.7 1.0 3.5 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal MSP1_C PF07462.11 GAN11321.1 - 2.1 7.0 3.3 3.3 6.3 3.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-C2H2 PF00096.26 GAN11322.1 - 2.8e-08 33.8 7.8 0.00014 22.1 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN11322.1 - 7e-07 29.4 1.4 7e-07 29.4 1.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN11322.1 - 0.00096 19.8 5.5 0.81 10.7 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN11322.1 - 0.025 14.6 0.1 0.025 14.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 GAN11322.1 - 0.24 12.1 5.7 0.38 11.4 0.2 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain Mpv17_PMP22 PF04117.12 GAN11324.1 - 1.9e-24 85.6 0.7 7.3e-24 83.8 0.2 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family FNIP PF05725.12 GAN11324.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 FNIP Repeat tRNA-synt_2c PF01411.19 GAN11325.1 - 3.1e-154 514.6 0.0 4e-154 514.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAN11325.1 - 5.7e-14 51.9 0.1 1.3e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAN11325.1 - 2.6e-05 24.7 2.9 6.1e-05 23.4 2.9 1.7 1 0 0 1 1 1 1 DHHA1 domain Lig_C PF18330.1 GAN11325.1 - 0.13 12.2 0.9 22 5.0 0.0 3.5 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region GST_N PF02798.20 GAN11326.1 - 6.6e-18 64.8 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAN11326.1 - 4.2e-17 62.3 0.1 1.4e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN11326.1 - 3.2e-14 53.0 0.0 8.6e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAN11326.1 - 3.6e-06 27.1 0.0 6.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAN11326.1 - 5.3e-05 23.2 0.0 7.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN11326.1 - 0.00023 21.3 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAN11326.1 - 0.024 14.8 0.0 0.17 12.1 0.0 2.3 3 0 0 3 3 3 0 Glutaredoxin HsbA PF12296.8 GAN11327.1 - 3.9e-22 78.9 9.7 3.9e-22 78.9 9.7 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF2959 PF11172.8 GAN11328.1 - 0.015 15.4 0.5 0.015 15.4 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2959) Bap31_Bap29_C PF18035.1 GAN11328.1 - 0.051 13.6 2.3 0.28 11.2 1.3 2.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain LPP PF04728.13 GAN11328.1 - 0.088 13.2 4.4 1.6 9.2 0.2 4.2 5 0 0 5 5 5 0 Lipoprotein leucine-zipper MbeD_MobD PF04899.12 GAN11328.1 - 1.3 9.2 0.0 1.3 9.2 0.0 4.1 5 0 0 5 5 5 0 MbeD/MobD like DUF948 PF06103.11 GAN11328.1 - 1.6 9.1 7.0 9.4 6.6 0.3 4.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.9 GAN11328.1 - 1.6 8.7 10.9 6.4 6.7 0.2 5.3 6 0 0 6 6 6 0 Apolipoprotein O Phasin PF05597.11 GAN11328.1 - 8.1 6.5 8.7 1.9 8.5 0.1 3.8 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Arrestin_C PF02752.22 GAN11329.1 - 8.8e-06 26.2 0.5 1.5e-05 25.5 0.5 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN11329.1 - 0.0022 18.1 0.9 0.034 14.2 0.2 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SNF2_N PF00176.23 GAN11330.1 - 1.3e-76 257.6 0.9 2.8e-76 256.5 0.6 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAN11330.1 - 5.9e-42 142.3 3.0 5.9e-42 142.3 3.0 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 GAN11330.1 - 1.1e-29 103.4 6.1 1.1e-29 103.4 6.1 3.6 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 GAN11330.1 - 2.9e-19 69.5 0.0 1e-18 67.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN11330.1 - 1.6e-11 44.6 0.2 1.7e-10 41.2 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAN11330.1 - 6.9e-05 22.6 0.1 0.00028 20.6 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF1086 PF06461.11 GAN11330.1 - 0.00024 21.0 0.1 0.0008 19.3 0.1 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) HDA2-3 PF11496.8 GAN11330.1 - 0.00027 20.2 0.0 0.00066 18.9 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAN11330.1 - 0.00048 19.9 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAN11330.1 - 0.001 18.3 3.2 0.0051 16.1 0.1 2.6 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 GAN11330.1 - 0.037 14.0 0.4 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAN11330.1 - 0.12 12.6 0.2 0.69 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 GAN11330.1 - 0.77 10.0 10.7 1.6 9.0 0.0 3.8 3 1 0 3 3 2 0 Myb-like DNA-binding domain Occludin_ELL PF07303.13 GAN11330.1 - 1.6 9.5 10.1 0.083 13.6 3.4 2.5 2 0 0 2 2 1 0 Occludin homology domain Orn_Arg_deC_N PF02784.16 GAN11331.1 - 8.3e-84 280.8 0.0 1e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAN11331.1 - 1.8e-22 79.4 0.0 2.3e-22 79.0 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 GAN11331.1 - 0.00018 21.0 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel polyprenyl_synt PF00348.17 GAN11332.1 - 2.8e-69 233.0 0.0 5.9e-69 232.0 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Sulfatase PF00884.23 GAN11333.1 - 4.7e-61 206.9 1.8 8.4e-61 206.0 1.8 1.4 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 GAN11333.1 - 7.1e-05 23.0 0.1 0.00023 21.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) QSregVF_b PF12843.7 GAN11333.1 - 0.0082 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor DUF229 PF02995.17 GAN11333.1 - 0.014 14.0 0.0 0.26 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Phosphodiest PF01663.22 GAN11333.1 - 0.049 13.2 1.0 0.46 10.0 1.0 2.2 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Mito_carr PF00153.27 GAN11334.1 - 4.2e-56 186.9 0.6 1.4e-23 82.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAN11334.1 - 0.0011 18.2 0.1 0.077 12.1 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease FH2 PF02181.23 GAN11335.1 - 8.3e-81 272.0 12.6 8.3e-81 272.0 12.6 4.4 4 1 0 4 4 4 2 Formin Homology 2 Domain Drf_GBD PF06371.13 GAN11335.1 - 8.4e-11 41.8 19.5 6.3e-06 25.9 0.0 4.7 4 0 0 4 4 4 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAN11335.1 - 1e-08 35.1 1.2 1e-08 35.1 1.2 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain Mg_trans_NIPA PF05653.14 GAN11336.1 - 5.7e-93 311.2 19.2 7.4e-93 310.9 19.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAN11336.1 - 2.5e-07 30.9 3.3 2.5e-07 30.9 3.3 2.5 2 1 0 2 2 2 1 EamA-like transporter family Glyco_transf_11 PF01531.16 GAN11336.1 - 0.14 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 Kelch_6 PF13964.6 GAN11338.1 - 1.1e-12 47.8 7.8 0.0064 16.7 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 GAN11338.1 - 1.3e-09 37.8 10.1 0.0036 17.2 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GAN11338.1 - 7.9e-08 31.8 0.2 0.00021 20.8 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAN11338.1 - 2e-07 30.7 3.7 0.5 10.4 0.0 5.8 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAN11338.1 - 1.6e-06 28.0 10.5 0.085 12.9 0.0 6.8 7 1 0 7 7 7 1 Galactose oxidase, central domain Kelch_3 PF13415.6 GAN11338.1 - 7.3e-06 26.1 11.5 0.019 15.3 0.1 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Gram_pos_anchor PF00746.21 GAN11338.1 - 0.41 10.6 1.8 1.1 9.3 1.8 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_M17 PF00883.21 GAN11339.1 - 7.6e-120 399.9 0.2 1.1e-119 399.3 0.2 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 GAN11339.1 - 1.6e-13 50.6 4.0 3.1e-13 49.7 4.0 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain CHASE2 PF05226.11 GAN11339.1 - 0.076 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain GATase_5 PF13507.6 GAN11340.1 - 2.4e-103 344.8 0.1 3.4e-103 344.3 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 GAN11340.1 - 2.3e-45 154.5 1.1 2e-30 106.0 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GAN11340.1 - 8.8e-32 109.5 0.0 1.6e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GAN11340.1 - 5.6e-22 78.0 0.0 2.1e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain TRP_2 PF08344.11 GAN11340.1 - 0.18 12.0 0.6 4.9 7.4 0.1 3.0 3 0 0 3 3 3 0 Transient receptor ion channel II EphA2_TM PF14575.6 GAN11342.1 - 0.017 16.0 0.0 0.057 14.3 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GRA6 PF05084.13 GAN11342.1 - 0.042 13.8 4.2 0.13 12.2 1.1 2.2 2 0 0 2 2 2 0 Granule antigen protein (GRA6) YajC PF02699.15 GAN11342.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF5075 PF16825.5 GAN11343.1 - 0.011 15.4 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 IGP family C-type lectin domain RabGAP-TBC PF00566.18 GAN11344.1 - 1e-33 116.8 0.4 1e-33 116.8 0.4 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TnpV PF14198.6 GAN11344.1 - 0.05 13.6 0.8 10 6.1 0.0 2.9 2 1 1 3 3 3 0 Transposon-encoded protein TnpV GatB_N PF02934.15 GAN11345.1 - 1.7e-106 355.6 0.1 2.1e-106 355.3 0.1 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GAN11345.1 - 5.7e-36 123.6 0.0 1e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 GatB domain Chorismate_synt PF01264.21 GAN11346.1 - 9.6e-139 461.6 0.1 1.1e-138 461.5 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase RE_AccI PF09545.10 GAN11346.1 - 0.25 10.3 0.0 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease Perilipin PF03036.16 GAN11347.1 - 9.2e-13 48.0 8.3 7.8e-07 28.5 0.2 2.4 1 1 1 2 2 2 2 Perilipin family MukF_M PF17192.4 GAN11347.1 - 0.0052 16.5 0.8 0.0095 15.7 0.8 1.4 1 0 0 1 1 1 1 MukF middle domain THRAP3_BCLAF1 PF15440.6 GAN11347.1 - 0.053 12.5 1.9 0.067 12.2 1.9 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Glyco_hydro_47 PF01532.20 GAN11348.1 - 2.7e-138 461.7 0.0 5.3e-137 457.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_pol_A_exo1 PF01612.20 GAN11349.1 - 3.5e-48 163.6 0.5 5.5e-48 163.0 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 GAN11349.1 - 9.4e-21 74.3 0.0 3.5e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 GAN11349.1 - 2.2e-12 46.8 0.0 1.4e-11 44.2 0.0 2.4 3 0 0 3 3 3 1 HRDC domain Ras PF00071.22 GAN11350.1 - 7.2e-49 165.5 0.2 9e-49 165.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAN11350.1 - 2.2e-37 127.9 0.1 3e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAN11350.1 - 6.2e-15 55.1 0.0 8.1e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAN11350.1 - 2.3e-10 40.2 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAN11350.1 - 3.3e-06 27.2 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAN11350.1 - 3.5e-06 26.6 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAN11350.1 - 5.8e-05 22.7 0.1 0.00015 21.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 GAN11350.1 - 0.00033 20.6 0.0 0.00043 20.3 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAN11350.1 - 0.00089 19.7 0.0 0.0015 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 GAN11350.1 - 0.0018 18.1 0.7 0.015 15.1 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 GAN11350.1 - 0.0024 17.9 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 GAN11350.1 - 0.011 15.6 1.9 0.27 11.1 0.3 2.6 1 1 2 3 3 3 0 RsgA GTPase YwhD PF08741.10 GAN11350.1 - 0.031 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 YwhD family RE_CfrBI PF09516.10 GAN11350.1 - 0.057 12.8 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 CfrBI restriction endonuclease NTPase_1 PF03266.15 GAN11350.1 - 0.059 13.3 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 GAN11350.1 - 0.066 12.7 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 GAN11350.1 - 0.073 13.1 0.2 0.2 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF2288 PF10052.9 GAN11350.1 - 0.073 13.2 0.2 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) AAA_24 PF13479.6 GAN11350.1 - 0.12 12.1 0.5 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAN11350.1 - 0.13 12.0 0.2 0.44 10.3 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Cerato-platanin PF07249.12 GAN11351.1 - 0.024 14.7 0.1 0.079 13.1 0.0 1.9 1 1 1 2 2 2 0 Cerato-platanin CDC27 PF09507.10 GAN11351.1 - 0.33 10.3 34.5 0.4 10.0 34.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Apt1 PF10351.9 GAN11351.1 - 2.7 6.8 20.8 4.1 6.1 20.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Fasciclin PF02469.22 GAN11353.1 - 2.8e-13 50.2 4.2 8.6e-11 42.2 0.8 2.7 2 1 0 2 2 2 2 Fasciclin domain NMD3 PF04981.13 GAN11354.1 - 3.8e-86 288.5 1.6 5.4e-86 288.0 1.6 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 GAN11354.1 - 0.055 13.5 7.9 0.067 13.2 3.4 2.6 1 1 1 2 2 2 0 Double zinc ribbon HLH PF00010.26 GAN11356.1 - 1.7e-17 63.1 2.1 1.7e-17 63.1 2.1 2.5 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain DUF5355 PF17306.2 GAN11356.1 - 0.029 13.4 0.1 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5355) ATG16 PF08614.11 GAN11356.1 - 2.4 8.3 10.8 4.6 7.4 10.8 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 GAN11356.1 - 4.8 7.4 7.7 0.99 9.6 3.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PfkB PF00294.24 GAN11357.1 - 8.4e-25 87.7 0.3 1.2e-13 51.1 0.3 2.6 2 1 1 3 3 3 2 pfkB family carbohydrate kinase zf-C2H2_2 PF12756.7 GAN11358.1 - 1.5e-06 28.4 7.8 0.014 15.7 0.7 3.4 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAN11358.1 - 0.0012 19.5 18.9 0.12 13.3 0.5 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN11358.1 - 0.031 14.8 20.7 0.4 11.2 1.1 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 GAN11358.1 - 0.068 13.3 0.2 12 6.1 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 GAN11358.1 - 0.073 13.4 17.7 0.083 13.2 4.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 GAN11358.1 - 0.11 12.4 3.0 0.61 10.0 0.5 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C4pol PF14260.6 GAN11358.1 - 0.16 12.4 5.5 1.4 9.5 0.7 2.7 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf_Hakai PF18408.1 GAN11358.1 - 0.21 11.3 8.6 0.25 11.1 0.6 2.8 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain FOXP-CC PF16159.5 GAN11358.1 - 0.72 10.5 10.3 2.4 8.8 1.2 3.6 2 2 1 4 4 4 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 GAN11358.1 - 0.79 10.3 0.1 0.21 12.1 2.3 4.7 5 0 0 5 5 5 0 Zinc-finger double domain ELO PF01151.18 GAN11359.1 - 2e-66 224.1 9.9 2.4e-66 223.8 9.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.8 GAN11359.1 - 0.13 12.3 1.4 0.75 9.9 0.6 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 4HBT PF03061.22 GAN11360.1 - 3.3e-08 33.8 0.0 7.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily WD40 PF00400.32 GAN11360.1 - 1.2 10.2 0.0 1.2 10.2 0.0 5.1 7 0 0 7 7 7 0 WD domain, G-beta repeat DUF5435 PF17503.2 GAN11362.1 - 0.074 12.8 0.2 0.074 12.8 0.2 2.9 4 0 0 4 4 4 0 Family of unknown function (DUF5435) LptF_LptG PF03739.14 GAN11362.1 - 3.9 6.2 8.8 7.3 5.3 8.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG 6PF2K PF01591.18 GAN11364.1 - 1.1e-69 234.2 0.9 1.5e-69 233.7 0.1 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAN11364.1 - 2.9e-33 115.2 0.0 1.1e-24 87.3 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAN11364.1 - 3.8e-06 27.1 0.0 9.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAN11364.1 - 0.0046 16.5 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF5128 PF17170.4 GAN11364.1 - 0.012 14.8 0.8 0.012 14.8 0.8 1.6 2 0 0 2 2 2 0 6-bladed beta-propeller AAA_17 PF13207.6 GAN11364.1 - 0.035 14.5 0.3 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAN11364.1 - 0.075 12.3 0.0 0.18 11.0 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin MFS_1 PF07690.16 GAN11365.1 - 2.2e-18 66.3 51.8 2.4e-18 66.2 46.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily PseudoU_synth_2 PF00849.22 GAN11366.1 - 3.3e-26 92.3 0.0 5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 GAN11366.1 - 0.039 13.7 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 S4 domain RRM_1 PF00076.22 GAN11367.1 - 6.3e-23 80.4 0.0 2.1e-10 40.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.6 GAN11369.1 - 1.6e-09 37.5 8.5 3e-09 36.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAN11369.1 - 7.7e-08 32.1 9.7 1.6e-07 31.1 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAN11369.1 - 5.6e-07 29.5 6.4 1.3e-06 28.3 6.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAN11369.1 - 7.1e-07 29.5 8.6 7.1e-07 29.5 8.6 2.2 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 GAN11369.1 - 1.3e-06 28.2 9.6 3.2e-06 27.0 9.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAN11369.1 - 3.1e-06 27.0 7.7 6.4e-06 25.9 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAN11369.1 - 8.9e-05 22.6 7.2 8.9e-05 22.6 7.2 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING BRCT PF00533.26 GAN11369.1 - 0.00032 21.0 0.0 0.0014 19.0 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Prok-RING_4 PF14447.6 GAN11369.1 - 0.0018 18.1 6.8 0.0018 18.1 6.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAN11369.1 - 0.0038 17.3 3.8 0.0081 16.3 3.8 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 GAN11369.1 - 0.0075 16.5 9.2 0.028 14.7 7.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 GAN11369.1 - 0.0082 16.0 2.2 0.015 15.2 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GAN11369.1 - 0.013 15.3 7.2 0.21 11.4 6.4 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain BRCT_2 PF16589.5 GAN11369.1 - 0.015 15.7 0.0 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DZR PF12773.7 GAN11369.1 - 0.019 15.0 7.1 0.051 13.6 7.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 GAN11369.1 - 0.052 13.4 3.4 0.1 12.4 3.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RTT107_BRCT_5 PF16770.5 GAN11369.1 - 0.12 12.3 0.0 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF1272 PF06906.11 GAN11369.1 - 0.15 12.2 9.2 0.12 12.5 6.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.6 GAN11369.1 - 0.45 10.0 0.1 0.45 10.0 0.1 3.0 2 1 0 2 2 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAN11369.1 - 1.5 9.0 6.5 0.74 10.0 3.7 2.0 2 0 0 2 2 1 0 Zinc ribbon domain zf-C3H2C3 PF17122.5 GAN11369.1 - 2.5 8.2 5.0 5 7.2 5.0 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_Tnp_IS91 PF14319.6 GAN11369.1 - 2.6 8.1 8.4 14 5.8 4.0 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain NOB1_Zn_bind PF08772.11 GAN11369.1 - 3.6 7.8 8.5 11 6.2 2.4 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RabGAP-TBC PF00566.18 GAN11370.1 - 4.2e-33 114.8 0.4 6.6e-33 114.2 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SUIM_assoc PF16619.5 GAN11371.1 - 0.018 15.1 12.6 0.053 13.6 2.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GRP PF07172.11 GAN11371.1 - 0.1 13.3 9.4 0.19 12.4 9.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family Ycf34 PF10718.9 GAN11371.1 - 1.5 9.5 4.3 1.2 9.8 0.1 2.2 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 CotH PF08757.11 GAN11375.1 - 1.1e-37 130.2 1.7 1.7e-37 129.7 1.7 1.2 1 0 0 1 1 1 1 CotH kinase protein Iron_transport PF10634.9 GAN11375.1 - 0.00029 21.0 0.6 0.0057 16.8 0.2 2.6 2 0 0 2 2 2 1 Fe2+ transport protein Fungal_trans PF04082.18 GAN11376.1 - 8.7e-40 136.4 0.0 1.8e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.29 GAN11377.1 - 6.5e-50 169.3 0.1 5.3e-49 166.4 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN11377.1 - 2.6e-23 82.5 0.2 1.1e-22 80.5 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 GAN11377.1 - 1.2e-20 73.5 3.6 1.2e-20 73.5 3.6 3.5 4 0 0 4 4 4 1 DBP10CT (NUC160) domain ResIII PF04851.15 GAN11377.1 - 3.5e-06 27.1 0.0 3.5e-06 27.1 0.0 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AlaDh_PNT_N PF05222.15 GAN11378.1 - 5.1e-32 111.0 0.0 7.8e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 GAN11378.1 - 0.00031 20.1 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RRM_1 PF00076.22 GAN11379.1 - 4.1e-16 58.5 0.0 7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KxDL PF10241.9 GAN11379.1 - 0.0006 20.0 0.8 0.00098 19.4 0.5 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein FTA4 PF13093.6 GAN11379.1 - 0.0051 16.7 0.6 0.0061 16.5 0.6 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Lge1 PF11488.8 GAN11379.1 - 0.033 14.4 4.3 0.1 12.8 3.4 2.1 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Uds1 PF15456.6 GAN11379.1 - 0.071 13.3 4.3 0.11 12.7 4.3 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF3987 PF13148.6 GAN11379.1 - 0.19 10.7 2.4 0.25 10.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Med9 PF07544.13 GAN11379.1 - 0.2 11.7 4.1 0.13 12.4 2.0 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.8 GAN11379.1 - 0.22 10.8 7.0 0.31 10.3 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 GAN11379.1 - 0.36 11.3 3.0 0.67 10.4 3.0 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 GAN11379.1 - 0.48 9.2 9.1 0.59 9.0 9.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 GAN11379.1 - 0.66 10.5 11.1 0.9 10.1 11.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 GAN11379.1 - 1.1 9.1 12.0 1 9.2 10.3 1.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 YabA PF06156.13 GAN11379.1 - 2.5 8.8 4.6 3.6 8.3 4.0 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 GAN11379.1 - 5.2 6.9 8.9 0.63 9.9 4.7 1.6 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 GAN11379.1 - 6.4 7.1 7.3 5.5 7.3 5.7 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 NCBP3 PF10309.9 GAN11380.1 - 0.0046 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 GAN11380.1 - 0.0056 16.7 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 RNA binding domain DUF2173 PF09941.9 GAN11381.1 - 0.0051 17.1 0.0 0.0061 16.8 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2173) Suf PF05843.14 GAN11382.1 - 2e-69 234.9 21.9 2e-69 234.9 21.9 7.6 3 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 GAN11382.1 - 0.00018 22.0 6.7 1.3 10.1 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat SUIM_assoc PF16619.5 GAN11382.1 - 0.0033 17.4 2.1 0.0033 17.4 2.1 5.9 5 1 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 TPR_17 PF13431.6 GAN11382.1 - 0.0039 17.5 0.6 26 5.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Gp58 PF07902.11 GAN11382.1 - 0.021 13.1 1.3 0.032 12.5 1.3 1.1 1 0 0 1 1 1 0 gp58-like protein TPR_2 PF07719.17 GAN11382.1 - 0.032 14.3 0.0 9 6.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAN11382.1 - 0.061 13.6 0.1 2.4 8.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAN11382.1 - 0.096 13.4 0.8 52 4.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RVT_1 PF00078.27 GAN11383.1 - 1.1e-25 90.5 0.0 3.3e-25 88.9 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 GAN11383.1 - 0.016 15.2 0.8 0.041 13.9 0.8 1.6 1 0 0 1 1 1 0 Pao retrotransposon peptidase RRM_1 PF00076.22 GAN11384.1 - 4.7e-18 64.8 0.1 6.7e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAN11384.1 - 0.00016 21.5 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Phage_terminase PF10668.9 GAN11384.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.4 5 0 0 5 5 5 0 Phage terminase small subunit ORC6 PF05460.13 GAN11384.1 - 7.1 5.8 9.7 11 5.2 9.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) E1-E2_ATPase PF00122.20 GAN11385.1 - 1.1e-24 87.0 0.0 3.3e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAN11385.1 - 1e-08 35.8 0.2 0.0023 18.2 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase SusF_SusE PF16411.5 GAN11385.1 - 0.13 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Outer membrane protein SusF_SusE HMG-CoA_red PF00368.18 GAN11386.1 - 4.5e-141 470.1 7.3 8.4e-141 469.2 7.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 GAN11386.1 - 2.5e-17 63.1 3.7 2.5e-17 63.1 3.7 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAN11386.1 - 1.2e-07 30.2 9.0 2.1e-07 29.5 9.0 1.3 1 0 0 1 1 1 1 Patched family HPIH PF13323.6 GAN11386.1 - 0.0057 16.5 2.0 0.036 13.9 0.1 2.7 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Aminotran_4 PF01063.19 GAN11388.1 - 2.1e-32 112.8 0.0 3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Vps39_2 PF10367.9 GAN11392.1 - 6.1e-36 123.2 0.6 5.8e-34 116.8 0.1 3.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 GAN11392.1 - 2e-33 116.2 0.0 3.8e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 GAN11392.1 - 2.8e-30 104.8 0.2 2.8e-30 104.8 0.2 4.4 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 GAN11392.1 - 1.4e-15 57.4 14.0 1.1e-10 41.6 2.5 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS TPR_14 PF13428.6 GAN11392.1 - 0.0084 16.8 1.7 6.9 7.8 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat HemX PF04375.14 GAN11392.1 - 0.014 14.7 0.2 0.027 13.8 0.2 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TPR_1 PF00515.28 GAN11392.1 - 0.046 13.6 1.5 5.8 6.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAN11392.1 - 0.1 12.7 4.3 23 5.3 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAN11392.1 - 0.13 12.6 2.1 50 4.3 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAN11392.1 - 0.69 10.2 3.4 34 4.9 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 GAN11393.1 - 0.0012 18.9 15.4 0.15 12.1 0.4 4.5 2 1 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus NST1 PF13945.6 GAN11394.1 - 5.6e-56 189.7 17.8 5.6e-56 189.7 17.8 3.8 3 1 1 4 4 4 1 Salt tolerance down-regulator SDA1 PF05285.12 GAN11394.1 - 0.002 17.6 26.2 0.002 17.6 26.2 4.1 3 1 0 3 3 3 1 SDA1 DEAD PF00270.29 GAN11395.1 - 1e-47 162.2 0.1 3.7e-47 160.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN11395.1 - 3.7e-24 85.2 0.0 3.1e-23 82.2 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAN11395.1 - 3.8e-19 68.7 0.3 6.9e-19 67.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAN11395.1 - 0.00014 21.9 0.0 0.00042 20.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_125 PF06824.11 GAN11396.1 - 1.3e-164 548.0 0.1 1.3e-164 548.0 0.1 1.6 2 0 0 2 2 2 1 Metal-independent alpha-mannosidase (GH125) ACBP PF00887.19 GAN11396.1 - 5.2e-23 81.1 0.1 2.2e-22 79.1 0.1 2.1 1 0 0 1 1 1 1 Acyl CoA binding protein BCNT PF07572.12 GAN11396.1 - 0.067 13.3 0.5 0.26 11.4 0.5 2.0 1 0 0 1 1 1 0 Bucentaur or craniofacial development ATP-cone PF03477.16 GAN11396.1 - 0.18 12.4 0.3 0.87 10.2 0.1 2.3 2 0 0 2 2 2 0 ATP cone domain SKG6 PF08693.10 GAN11396.1 - 0.36 10.3 2.0 0.64 9.5 2.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DivIC PF04977.15 GAN11396.1 - 3.7 7.4 14.5 6.1 6.7 0.9 3.6 3 0 0 3 3 3 0 Septum formation initiator Atg8 PF02991.16 GAN11398.1 - 3.1e-36 123.7 0.0 3.5e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GAN11398.1 - 3e-05 24.4 0.0 3.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 zf-SNAP50_C PF12251.8 GAN11399.1 - 7.2e-46 156.4 7.3 1.1e-45 155.8 7.3 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal SET PF00856.28 GAN11400.1 - 4.4e-18 66.2 0.0 7.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 GAN11400.1 - 6e-05 23.7 0.0 0.00016 22.4 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding DDE_3 PF13358.6 GAN11401.1 - 8.5e-08 32.1 0.0 2.2e-07 30.7 0.0 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 GAN11401.1 - 0.026 14.8 0.0 0.099 12.9 0.0 2.0 1 1 1 2 2 2 0 Transposase ALIX_LYPXL_bnd PF13949.6 GAN11402.1 - 0.004 16.5 1.4 0.004 16.5 1.4 2.6 1 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV kleA_kleC PF17383.2 GAN11402.1 - 0.088 13.1 1.3 0.2 12.0 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A TMF_DNA_bd PF12329.8 GAN11402.1 - 0.11 12.5 0.3 0.11 12.5 0.3 3.6 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 GAN11402.1 - 0.37 11.0 24.3 0.79 9.9 5.3 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF3708 PF12501.8 GAN11402.1 - 0.68 9.7 3.7 0.7 9.7 1.9 1.9 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter RuvC PF02075.17 GAN11402.1 - 0.8 9.6 5.6 0.55 10.1 2.0 2.4 1 1 1 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC Seryl_tRNA_N PF02403.22 GAN11402.1 - 1.5 9.1 22.4 1.1 9.6 5.5 4.3 2 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 GAN11402.1 - 1.8 8.7 29.5 0.19 11.9 5.4 3.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RPW8 PF05659.11 GAN11402.1 - 2 8.1 9.6 0.092 12.4 1.2 3.1 4 1 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TORC_N PF12884.7 GAN11402.1 - 2 9.3 15.5 0.48 11.2 1.0 3.5 3 1 1 4 4 3 0 Transducer of regulated CREB activity, N terminus Metal_resist PF13801.6 GAN11402.1 - 2.1 8.5 6.4 4 7.7 0.1 3.2 4 0 0 4 4 4 0 Heavy-metal resistance Raf1_N PF18578.1 GAN11402.1 - 3.1 8.3 8.3 0.22 12.0 1.0 2.8 3 2 0 3 3 3 0 Rubisco accumulation factor 1 alpha helical domain DUF3452 PF11934.8 GAN11402.1 - 3.7 7.1 10.9 0.7 9.4 1.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) DUF4806 PF16064.5 GAN11402.1 - 5.1 7.5 7.6 5 7.5 0.2 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4806) Mcp5_PH PF12814.7 GAN11403.1 - 3.2e-26 91.8 0.7 1.5e-25 89.7 0.7 2.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 GAN11403.1 - 6e-06 26.7 2.8 1.1e-05 25.9 0.9 2.4 2 0 0 2 2 2 1 PH domain tRNA-synt_2d PF01409.20 GAN11403.1 - 0.045 13.2 1.8 0.97 8.9 0.7 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PH_2 PF08458.10 GAN11403.1 - 0.076 13.4 0.1 0.076 13.4 0.1 3.4 2 1 1 3 3 3 0 Plant pleckstrin homology-like region Macoilin PF09726.9 GAN11403.1 - 0.32 9.5 38.5 0.59 8.6 38.5 1.5 1 0 0 1 1 1 0 Macoilin family RNB PF00773.19 GAN11404.1 - 9.5e-57 192.8 0.2 1.3e-56 192.3 0.2 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAN11404.1 - 1.5e-19 69.7 0.0 7.2e-19 67.6 0.0 2.0 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 GAN11404.1 - 1.7e-10 40.9 0.1 1.2e-05 25.3 0.1 2.9 3 0 0 3 3 3 2 Cold shock domain Rrp44_CSD1 PF17216.3 GAN11404.1 - 8.1e-08 32.1 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 GAN11404.1 - 0.039 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain RNB PF00773.19 GAN11405.1 - 2.1e-28 99.6 1.0 4.2e-28 98.6 0.0 1.9 2 0 0 2 2 2 1 RNB domain Rrp44_S1 PF17215.3 GAN11405.1 - 2.8e-07 30.4 0.0 1.1e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 S1 domain LRR_6 PF13516.6 GAN11406.1 - 2.8e-06 26.9 4.5 0.24 11.5 0.0 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 GAN11406.1 - 0.00032 21.0 1.0 5 7.7 0.0 4.6 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) TIG PF01833.24 GAN11407.1 - 1.1e-11 44.6 1.8 6.8e-10 38.9 0.1 3.5 3 0 0 3 3 3 1 IPT/TIG domain Ank_2 PF12796.7 GAN11407.1 - 4.4e-08 33.6 0.1 8.3e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAN11407.1 - 4.3e-07 30.4 0.1 6.7e-05 23.4 0.1 2.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAN11407.1 - 1.3e-05 25.4 0.1 0.03 14.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GAN11407.1 - 3e-05 24.1 0.3 0.61 10.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAN11407.1 - 0.00034 20.9 0.4 0.01 16.1 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAN11408.1 - 8e-18 64.6 0.0 5.1e-06 26.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAN11408.1 - 1.3e-16 61.0 0.1 8.2e-10 39.2 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN11408.1 - 3.4e-13 48.5 0.0 2.2e-06 27.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAN11408.1 - 5.5e-12 45.7 0.1 2.3e-08 34.2 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAN11408.1 - 4.4e-11 42.7 0.0 3.2e-06 27.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat His_biosynth PF00977.21 GAN11408.1 - 0.011 15.2 0.3 0.046 13.2 0.0 2.1 2 1 0 3 3 3 0 Histidine biosynthesis protein Erythro_esteras PF05139.14 GAN11408.1 - 0.07 12.9 1.6 0.077 12.8 1.6 1.3 1 1 0 1 1 1 0 Erythromycin esterase Ricin_B_lectin PF00652.22 GAN11409.1 - 5.4e-25 88.1 9.6 4.7e-12 46.3 0.4 3.4 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 GAN11409.1 - 4.7e-17 62.5 3.6 3.7e-08 34.0 0.1 2.8 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like GRIP PF01465.20 GAN11409.1 - 4.3e-11 42.6 1.1 8.7e-11 41.6 1.1 1.6 1 0 0 1 1 1 1 GRIP domain DUF2155 PF09923.9 GAN11409.1 - 0.059 13.6 0.3 0.23 11.7 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF3584 PF12128.8 GAN11409.1 - 0.35 8.3 53.8 0.023 12.3 47.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Rab_bind PF16704.5 GAN11409.1 - 0.52 10.4 20.3 0.66 10.1 0.8 5.2 4 1 0 4 4 4 0 Rab binding domain Filament PF00038.21 GAN11409.1 - 2.6 7.5 58.0 0.99 8.9 22.5 4.0 2 1 1 3 3 3 0 Intermediate filament protein Nuc_sug_transp PF04142.15 GAN11410.1 - 3.4e-111 371.4 15.2 3.9e-111 371.2 15.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAN11410.1 - 8.7e-08 32.4 21.7 9.7e-06 25.8 1.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 GAN11410.1 - 0.00069 19.3 1.1 0.00069 19.3 1.1 2.2 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter TPT PF03151.16 GAN11410.1 - 0.0084 15.5 1.2 0.0084 15.5 1.2 3.0 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 GAN11410.1 - 0.009 15.2 2.1 0.009 15.2 2.1 2.6 1 1 1 2 2 2 2 UAA transporter family PUNUT PF16913.5 GAN11410.1 - 0.54 9.4 19.5 1.5 8.0 19.5 1.7 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport DUF3655 PF12379.8 GAN11411.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) Fungal_trans PF04082.18 GAN11412.1 - 3.3e-10 39.4 0.1 3.3e-10 39.4 0.1 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN11412.1 - 0.021 14.9 11.7 0.047 13.8 11.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IF4E PF01652.18 GAN11413.1 - 3.2e-54 183.0 1.9 4.4e-54 182.6 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S6e PF01092.19 GAN11414.1 - 1.2e-60 203.0 0.0 1.4e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e DAO PF01266.24 GAN11415.1 - 3.1e-44 152.0 0.0 3.7e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAN11415.1 - 9.5e-08 32.2 0.0 1e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAN11415.1 - 0.0023 17.1 0.0 0.069 12.2 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAN11415.1 - 0.0028 17.7 0.0 0.045 13.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAN11415.1 - 0.0093 15.2 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAN11415.1 - 0.062 12.5 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FliT PF05400.13 GAN11416.1 - 0.1 13.4 0.1 4.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT RT_RNaseH PF17917.1 GAN11418.1 - 1.3e-28 99.4 0.1 4.5e-28 97.6 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN11418.1 - 8.2e-27 93.2 0.0 2.6e-26 91.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GAN11418.1 - 7.9e-17 61.5 0.1 6.6e-16 58.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GAN11418.1 - 2.5e-15 56.6 0.4 5.4e-15 55.5 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAN11418.1 - 5e-10 39.3 2.4 5.7e-10 39.2 0.9 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 GAN11418.1 - 4.2e-09 36.2 0.2 1.4e-08 34.5 0.2 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotran_gag_2 PF14223.6 GAN11418.1 - 0.031 13.9 0.0 0.12 12.0 0.0 2.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 GAN11418.1 - 0.04 14.2 0.0 0.31 11.4 0.0 2.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-H2C2 PF09337.10 GAN11418.1 - 0.12 12.6 2.2 0.36 11.1 2.2 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Mtf2_C PF14061.6 GAN11418.1 - 0.15 12.3 0.1 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Cytochrome_B PF00033.19 GAN11419.1 - 2e-82 275.6 13.1 2e-82 275.6 13.1 2.2 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 GAN11419.1 - 3.6e-42 144.2 13.2 5.1e-42 143.7 9.9 2.4 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 GAN11419.1 - 1.3e-38 131.4 0.9 1.3e-38 131.4 0.9 2.9 4 0 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Ni_hydr_CYTB PF01292.20 GAN11419.1 - 0.0017 18.0 3.6 0.0017 18.0 3.6 3.7 1 1 0 2 2 2 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 GAN11419.1 - 0.016 15.7 3.8 0.016 15.7 3.8 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) Thr_synth_N PF14821.6 GAN11420.1 - 1.3e-28 99.0 0.0 3.1e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 GAN11420.1 - 7.4e-13 48.6 0.0 2.2e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF421 PF04239.12 GAN11420.1 - 0.074 12.8 0.2 5.9 6.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF421) WRKY PF03106.15 GAN11421.1 - 1.9e-08 34.4 3.5 2.2e-08 34.2 2.0 1.9 2 0 0 2 2 2 1 WRKY DNA -binding domain Enterotoxin_HS1 PF08090.11 GAN11421.1 - 1.1 9.3 3.0 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Herpes_UL3 PF03369.13 GAN11422.1 - 0.0041 17.7 0.1 0.0048 17.4 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus UL3 protein Ribosomal_L20 PF00453.18 GAN11422.1 - 0.031 14.3 0.5 0.047 13.8 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L20 Kinesin PF00225.23 GAN11423.1 - 8.2e-69 232.1 0.1 8.2e-69 232.1 0.1 2.3 2 0 0 2 2 2 1 Kinesin motor domain Speriolin_N PF15058.6 GAN11423.1 - 0.027 14.6 0.3 0.068 13.3 0.3 1.7 1 0 0 1 1 1 0 Speriolin N terminus DUF1664 PF07889.12 GAN11423.1 - 2.5 8.1 15.8 0.47 10.5 7.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PAP2 PF01569.21 GAN11424.1 - 7.2e-31 106.8 1.2 7.2e-31 106.8 1.2 2.4 1 1 1 2 2 2 1 PAP2 superfamily TPPK_C PF12555.8 GAN11424.1 - 0.013 15.5 3.8 0.013 15.5 3.8 2.4 1 1 1 2 2 2 0 Thiamine pyrophosphokinase C terminal AA_permease_2 PF13520.6 GAN11424.1 - 0.021 13.6 4.1 0.021 13.7 0.7 2.0 2 0 0 2 2 2 0 Amino acid permease DUF805 PF05656.14 GAN11424.1 - 0.24 11.8 4.4 11 6.5 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PAP2_3 PF14378.6 GAN11424.1 - 0.6 9.8 13.9 0.044 13.5 2.8 3.2 1 1 2 3 3 3 0 PAP2 superfamily DUF2207 PF09972.9 GAN11424.1 - 2.4 6.8 4.1 1.2 7.8 1.8 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PAP2_C PF14360.6 GAN11424.1 - 3.6 8.2 9.8 0.28 11.8 1.4 2.9 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DUF4231 PF14015.6 GAN11424.1 - 6.1 7.4 5.2 65 4.1 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Glucos_trans_II PF14264.6 GAN11424.1 - 7.7 5.8 10.7 6.9 5.9 4.9 2.5 2 1 0 2 2 2 0 Glucosyl transferase GtrII ACPS PF01648.20 GAN11425.1 - 0.035 14.2 0.3 0.051 13.7 0.3 1.4 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily COMM_domain PF07258.14 GAN11425.1 - 0.067 13.3 2.8 0.11 12.6 2.8 1.3 1 0 0 1 1 1 0 COMM domain FAM219A PF15260.6 GAN11425.1 - 0.07 13.5 1.5 0.091 13.1 1.5 1.2 1 0 0 1 1 1 0 Protein family FAM219A MtaB PF12176.8 GAN11425.1 - 0.13 11.0 1.6 0.16 10.7 1.6 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit FKBP_C PF00254.28 GAN11426.1 - 1.2e-25 89.7 0.0 2.2e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 GAN11426.1 - 3.6e-14 51.9 12.0 2.3e-06 27.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAN11426.1 - 6.5e-09 35.2 11.8 0.0013 18.6 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN11426.1 - 1.6e-08 34.1 3.9 7.7e-06 25.5 0.3 2.6 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 GAN11426.1 - 7.7e-08 32.7 6.3 2.1e-06 28.1 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAN11426.1 - 1.4e-06 28.3 8.5 0.0083 16.2 1.9 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 GAN11426.1 - 1.5e-06 28.3 4.2 6.9e-06 26.2 4.2 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAN11426.1 - 1.5e-06 27.8 0.4 0.0028 17.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN11426.1 - 3.4e-06 26.8 13.8 0.0039 17.3 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN11426.1 - 5.1e-06 26.7 4.0 8.9e-06 25.9 0.8 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN11426.1 - 9.2e-06 26.2 0.8 1.6e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAN11426.1 - 2e-05 24.6 0.4 8.9e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAN11426.1 - 0.0067 17.2 0.4 0.28 12.1 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN11426.1 - 0.017 15.7 5.4 0.64 10.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAN11426.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DNA_ligase_IV PF11411.8 GAN11426.1 - 0.12 12.5 0.6 0.33 11.1 0.2 2.0 2 0 0 2 2 1 0 DNA ligase IV FKBP_N PF01346.18 GAN11426.1 - 6.1 7.9 9.1 14 6.7 0.0 2.7 3 0 0 3 3 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase RTA1 PF04479.13 GAN11427.1 - 3.3e-49 167.3 13.9 3.3e-49 167.3 13.9 1.7 1 1 1 2 2 2 1 RTA1 like protein DUF4131 PF13567.6 GAN11427.1 - 0.59 9.8 11.3 1.5 8.4 3.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) TMEM208_SND2 PF05620.11 GAN11427.1 - 2.1 8.1 4.5 42 3.9 2.8 2.6 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 MHYT PF03707.16 GAN11427.1 - 2.6 8.3 6.1 11 6.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat RTA1 PF04479.13 GAN11428.1 - 2.8e-50 170.8 10.8 2.8e-50 170.8 10.8 2.0 1 1 1 2 2 2 2 RTA1 like protein Proton_antipo_M PF00361.20 GAN11429.1 - 4.8e-80 268.9 22.9 4.8e-80 268.9 22.9 1.9 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 GAN11429.1 - 1.6e-19 69.7 3.6 1.6e-19 69.7 3.6 3.8 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus TPR_2 PF07719.17 GAN11430.1 - 1.3e-18 65.5 2.1 3e-05 23.8 0.3 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAN11430.1 - 1.3e-12 47.0 3.2 1.6e-05 24.5 0.4 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAN11430.1 - 1.3e-12 48.0 0.2 0.02 15.4 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAN11430.1 - 1.2e-09 37.7 0.9 8.5e-05 22.2 0.3 3.6 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 GAN11430.1 - 1.6e-09 37.8 0.0 3.1 8.9 0.0 6.6 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAN11430.1 - 2.8e-09 36.5 8.4 0.013 15.7 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAN11430.1 - 4.3e-08 33.3 5.3 8.9e-05 22.7 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAN11430.1 - 7.7e-07 29.3 0.1 0.24 11.7 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAN11430.1 - 9.2e-07 28.8 3.5 0.12 12.8 0.0 5.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAN11430.1 - 1.3e-06 28.4 2.7 0.064 13.4 0.0 5.7 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAN11430.1 - 1.6e-06 27.6 1.5 0.027 13.7 0.4 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAN11430.1 - 2.8e-05 24.7 0.0 0.42 11.3 0.0 4.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAN11430.1 - 7.4e-05 23.1 5.1 0.2 12.4 0.0 6.1 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAN11430.1 - 0.00022 21.0 0.7 7.7 6.8 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2538 PF10804.8 GAN11430.1 - 0.026 14.3 0.0 0.083 12.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) TPR_10 PF13374.6 GAN11430.1 - 0.13 12.1 7.7 0.54 10.2 0.5 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Hexokinase_1 PF00349.21 GAN11431.1 - 2.9e-65 219.9 0.1 3.3e-65 219.7 0.1 1.0 1 0 0 1 1 1 1 Hexokinase Bac_DNA_binding PF00216.21 GAN11431.1 - 0.00081 19.5 0.0 0.063 13.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 GAN11431.1 - 0.093 12.6 0.1 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 PqqD PF05402.12 GAN11431.1 - 0.13 12.6 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Integrase_Zn PF02022.19 GAN11431.1 - 0.13 12.3 1.7 0.13 12.2 0.3 1.8 2 0 0 2 2 2 0 Integrase Zinc binding domain NAD_binding_4 PF07993.12 GAN11432.1 - 2.7e-15 56.2 0.0 4.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 GAN11432.1 - 1.1e-10 41.6 0.0 4.4e-10 39.7 0.0 2.1 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 GAN11432.1 - 1.5e-05 24.6 0.0 3.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase HTH_23 PF13384.6 GAN11432.1 - 0.12 12.3 0.8 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain PIF1 PF05970.14 GAN11433.1 - 1.7e-105 353.2 0.0 2.4e-105 352.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 GAN11433.1 - 2.6e-10 40.3 0.0 9.4e-10 38.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAN11433.1 - 5e-05 23.7 0.2 0.00044 20.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain DUF2075 PF09848.9 GAN11433.1 - 0.0074 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 GAN11433.1 - 0.032 14.6 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PMP1_2 PF08114.11 GAN11433.1 - 4.5 7.1 4.5 11 5.9 4.5 1.6 1 0 0 1 1 1 0 ATPase proteolipid family HAP1_N PF04849.13 GAN11435.1 - 0.63 9.2 44.3 4.6 6.4 44.3 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 GAN11435.1 - 3.6 6.8 18.1 6.6 6.0 18.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GPI-anchored PF10342.9 GAN11436.1 - 0.0017 19.0 0.1 0.003 18.3 0.0 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Thioredoxin PF00085.20 GAN11437.1 - 1.5e-55 185.5 2.0 1.3e-28 99.0 0.3 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 GAN11437.1 - 6.9e-31 107.6 4.1 1e-21 77.7 0.5 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAN11437.1 - 3.9e-11 43.4 1.4 0.0091 16.4 0.0 4.1 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAN11437.1 - 1.1e-08 35.3 1.6 0.019 15.3 0.0 4.9 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GAN11437.1 - 2.1e-08 34.2 0.2 0.0046 17.1 0.1 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 GAN11437.1 - 3.3e-07 29.9 1.3 0.001 18.5 0.1 2.8 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GAN11437.1 - 2.6e-06 27.4 0.7 0.017 15.0 0.1 3.0 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.13 GAN11437.1 - 0.00025 21.2 0.3 0.51 10.5 0.0 2.7 3 0 0 3 3 3 2 ERp29, N-terminal domain Redoxin PF08534.10 GAN11437.1 - 0.0014 18.4 0.5 3 7.5 0.1 3.2 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 GAN11437.1 - 0.17 11.9 0.9 1.2 9.3 0.3 2.4 2 0 0 2 2 2 0 Thioredoxin domain zf-FPG_IleRS PF06827.14 GAN11437.1 - 2.1 8.3 6.1 4.2 7.3 0.6 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Ribonuc_P_40 PF08584.11 GAN11438.1 - 1.7e-50 171.9 0.4 2.3e-50 171.5 0.4 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit zf-C2H2 PF00096.26 GAN11439.1 - 9.9e-13 47.8 21.0 0.00024 21.4 1.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN11439.1 - 1.2e-10 41.2 17.6 0.00075 20.1 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN11439.1 - 5.3e-08 32.9 16.6 2e-05 24.8 0.1 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAN11439.1 - 1.1e-07 31.7 10.5 2.6e-06 27.3 0.7 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAN11439.1 - 3.9e-06 27.0 11.3 0.02 15.2 1.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 GAN11439.1 - 0.014 16.1 10.5 0.21 12.3 1.1 3.9 2 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats Phage_T4_Gp30_7 PF06919.11 GAN11439.1 - 0.041 14.0 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Phage Gp30.7 protein zf_ZIC PF18366.1 GAN11439.1 - 0.11 12.6 6.0 0.49 10.5 0.3 2.7 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-met PF12874.7 GAN11439.1 - 0.16 12.4 0.5 0.16 12.4 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 GAN11439.1 - 0.25 11.1 12.6 0.78 9.5 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 GAN11439.1 - 0.32 11.1 8.0 0.88 9.7 1.0 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_8 PF15909.5 GAN11439.1 - 0.69 10.3 4.7 1.4 9.2 3.8 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon Fer4_16 PF13484.6 GAN11439.1 - 6.2 7.8 9.6 3.2 8.8 1.9 3.1 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain zf-MYST PF17772.1 GAN11439.1 - 9.2 6.0 7.2 11 5.8 0.6 3.2 2 1 1 3 3 3 0 MYST family zinc finger domain DUF4112 PF13430.6 GAN11440.1 - 2.2e-27 95.4 0.4 3e-27 94.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF5086 PF16985.5 GAN11440.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5086) Peptidase_C48 PF02902.19 GAN11441.1 - 5.4e-18 65.6 4.5 5.4e-18 65.6 4.5 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF5094 PF17015.5 GAN11441.1 - 0.61 10.2 9.8 1.5 8.9 9.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) BRF1 PF07741.13 GAN11441.1 - 0.77 10.1 9.5 1.5 9.2 9.5 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain MFS_1 PF07690.16 GAN11442.1 - 2.6e-24 85.8 39.1 2.6e-24 85.8 39.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN11442.1 - 1.9e-13 50.1 2.2 1.9e-13 50.1 2.2 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAN11442.1 - 1.7e-07 30.1 21.5 4.7e-07 28.6 21.5 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAN11442.1 - 0.0058 15.0 10.1 0.082 11.2 1.3 2.9 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Lactate_perm PF02652.14 GAN11443.1 - 4.9e-119 398.4 23.3 6e-67 226.6 12.3 2.1 2 0 0 2 2 2 2 L-lactate permease DUF4199 PF13858.6 GAN11443.1 - 0.78 10.1 0.0 0.78 10.1 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF4199) F-box PF00646.33 GAN11444.1 - 2.1e-06 27.5 2.2 1.6e-05 24.6 0.0 3.0 3 0 0 3 3 3 1 F-box domain EF_assoc_1 PF08355.12 GAN11444.1 - 0.0047 16.5 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_7 PF13499.6 GAN11444.1 - 0.0047 17.3 0.1 0.014 15.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair F-box-like PF12937.7 GAN11444.1 - 0.005 16.7 0.2 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like EF-hand_1 PF00036.32 GAN11444.1 - 0.041 13.4 0.6 0.041 13.4 0.6 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 GAN11444.1 - 0.097 12.7 0.5 0.097 12.7 0.5 2.7 2 0 0 2 2 2 0 EF-hand domain DUF3367 PF11847.8 GAN11445.1 - 0.018 12.9 0.1 0.027 12.3 0.1 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase SLATT_5 PF18160.1 GAN11445.1 - 0.033 13.5 0.0 0.033 13.5 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Tmemb_170 PF10190.9 GAN11446.1 - 1.6e-11 44.5 20.1 4.1e-09 36.8 13.6 2.1 1 1 1 2 2 2 2 Putative transmembrane protein 170 ThrE PF06738.12 GAN11447.1 - 1.8e-59 201.0 16.7 1.6e-52 178.3 2.6 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAN11447.1 - 1.7e-11 44.4 8.6 1.7e-11 44.4 8.6 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE RabGAP-TBC PF00566.18 GAN11449.1 - 8.4e-35 120.4 0.3 8.4e-35 120.4 0.3 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 GAN11449.1 - 2.2e-28 98.4 1.7 1.5e-19 69.9 0.4 2.8 2 0 0 2 2 2 2 GRAM domain EF-hand_6 PF13405.6 GAN11449.1 - 0.0019 18.0 1.4 1.4 9.1 0.4 3.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAN11449.1 - 0.0081 15.6 0.3 0.82 9.4 0.4 3.4 2 0 0 2 2 2 1 EF hand DUF5329 PF17263.2 GAN11449.1 - 0.016 15.4 1.0 6.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5329) PSD4 PF07631.11 GAN11449.1 - 0.036 14.6 3.5 0.63 10.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) EF-hand_7 PF13499.6 GAN11449.1 - 1.4 9.4 15.0 0.11 13.0 2.3 4.5 2 1 1 3 3 3 0 EF-hand domain pair C2 PF00168.30 GAN11450.1 - 1.4e-20 73.5 1.6 4e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain Methyltransf_11 PF08241.12 GAN11452.1 - 9.4e-14 51.8 0.0 1.8e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN11452.1 - 2.8e-11 44.0 0.0 8.5e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN11452.1 - 6.2e-08 32.7 0.0 9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN11452.1 - 3e-06 27.1 0.0 6.1e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN11452.1 - 3.6e-06 27.6 0.0 9.7e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAN11452.1 - 0.00024 20.5 0.0 0.00055 19.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 GAN11452.1 - 0.026 13.5 0.1 0.16 10.8 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Metallophos PF00149.28 GAN11453.1 - 5.2e-08 33.6 0.1 1.1e-07 32.6 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0182 PF03699.13 GAN11453.1 - 0.11 10.5 0.3 0.17 10.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Far-17a_AIG1 PF04750.14 GAN11454.1 - 0.077 12.3 10.1 0.093 12.0 10.1 1.1 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein Phage_holin_3_6 PF07332.11 GAN11454.1 - 3.8 7.6 5.2 5.6 7.0 5.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ABC_tran PF00005.27 GAN11455.1 - 1.9e-12 47.8 0.0 3.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Kinesin PF00225.23 GAN11456.1 - 3.2e-93 312.3 5.2 7.3e-93 311.1 5.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAN11456.1 - 5.1e-21 75.2 0.8 1.5e-18 67.2 0.1 3.0 2 0 0 2 2 2 2 Microtubule binding DSBA PF01323.20 GAN11458.1 - 0.011 15.6 6.4 0.016 15.0 6.0 1.3 1 1 0 1 1 1 0 DSBA-like thioredoxin domain SCP2 PF02036.17 GAN11459.1 - 1.1e-24 86.8 1.0 1.3e-24 86.6 1.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAN11459.1 - 0.00055 20.2 0.1 0.00078 19.7 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Peptidase_C107 PF17222.3 GAN11459.1 - 0.064 12.2 0.0 0.074 12.0 0.0 1.1 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 NmrA PF05368.13 GAN11460.1 - 1.9e-12 47.2 0.0 6.5e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAN11460.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ACBP PF00887.19 GAN11461.1 - 1.8e-16 60.1 0.0 2.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ribosomal_L22 PF00237.19 GAN11462.1 - 1.5e-39 134.3 0.1 2e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e BolA PF01722.18 GAN11465.1 - 2.8e-18 65.9 0.1 5.2e-18 65.1 0.1 1.4 1 1 0 1 1 1 1 BolA-like protein EI24 PF07264.11 GAN11466.1 - 7.1e-06 26.4 2.1 7.1e-06 26.4 2.1 1.8 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) 3HCDH_N PF02737.18 GAN11466.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2633 PF11119.8 GAN11466.1 - 0.048 13.6 0.3 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Multi_Drug_Res PF00893.19 GAN11466.1 - 1.3 9.8 6.3 19 6.0 0.2 3.4 3 1 0 3 3 3 0 Small Multidrug Resistance protein Glyco_hydro_3_C PF01915.22 GAN11467.1 - 2.8e-59 200.5 0.0 5.9e-59 199.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAN11467.1 - 8.2e-44 150.3 0.1 1.2e-43 149.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAN11467.1 - 1.5e-18 66.6 0.1 3.4e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain URO-D PF01208.17 GAN11468.1 - 4.6e-129 430.5 0.0 5.2e-129 430.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Cid2 PF09774.9 GAN11469.1 - 0.0086 16.5 0.6 0.01 16.3 0.6 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 PAC2 PF09754.9 GAN11470.1 - 1.2e-23 84.2 0.0 2.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 PAC2 family DUF1635 PF07795.11 GAN11470.1 - 0.34 10.8 7.8 0.73 9.6 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) EB1 PF03271.17 GAN11471.1 - 2.6e-16 59.5 2.0 4.8e-16 58.7 2.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GAN11471.1 - 5.6e-06 26.5 0.7 9.1e-06 25.8 0.7 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 GAN11471.1 - 0.044 13.9 0.4 0.075 13.2 0.4 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein TB2_DP1_HVA22 PF03134.19 GAN11472.1 - 3.2e-15 55.8 3.0 8.5e-15 54.4 3.0 1.8 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Cyclin_N PF00134.23 GAN11472.1 - 5.8e-08 32.5 0.4 1.2e-07 31.5 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAN11472.1 - 0.0092 16.4 3.9 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 Cyclin DUF5353 PF17304.2 GAN11472.1 - 0.027 14.2 0.3 0.077 12.8 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5353) CDK2AP PF09806.9 GAN11472.1 - 0.14 12.2 2.3 0.27 11.3 2.3 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SLM4 PF16818.5 GAN11472.1 - 0.15 12.0 3.9 0.12 12.4 0.5 2.5 2 1 0 2 2 2 0 Protein SLM4 IMUP PF15761.5 GAN11472.1 - 0.37 11.5 5.5 0.75 10.5 5.5 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Fungal_trans PF04082.18 GAN11473.1 - 1.3e-19 70.3 0.5 2.5e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAN11473.1 - 6.6e-10 38.9 10.3 1.1e-09 38.2 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRAS PF15798.5 GAN11473.1 - 0.059 14.0 3.3 0.2 12.2 3.3 1.9 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 Ank_4 PF13637.6 GAN11474.1 - 3.3e-12 46.7 3.8 4.1e-06 27.2 0.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAN11474.1 - 1.5e-10 41.0 2.3 3.1e-08 33.7 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 GAN11474.1 - 1.8e-10 41.3 0.9 2.6e-10 40.8 0.9 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAN11474.1 - 3.2e-08 33.2 0.3 3.7e-05 23.8 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAN11474.1 - 6.8e-06 26.3 0.3 1.4e-05 25.3 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PG_isomerase_N PF18353.1 GAN11474.1 - 0.018 15.5 0.2 0.024 15.0 0.2 1.2 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain DUF4791 PF16039.5 GAN11474.1 - 0.033 13.7 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) RGS PF00615.19 GAN11475.1 - 5.5e-22 78.3 0.1 4.9e-21 75.2 0.1 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 GAN11475.1 - 1.8e-14 53.5 0.1 1e-08 35.1 0.1 3.4 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Sulfotransfer_3 PF13469.6 GAN11475.1 - 0.75 10.1 5.7 0.16 12.4 0.3 2.4 3 0 0 3 3 3 0 Sulfotransferase family GST_C_2 PF13410.6 GAN11477.1 - 8.4e-06 25.7 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAN11477.1 - 0.00046 20.5 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAN11477.1 - 0.002 18.3 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAN11477.1 - 0.0053 16.5 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Osmo_CC PF08946.10 GAN11477.1 - 0.02 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil GST_N PF02798.20 GAN11477.1 - 0.027 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN11477.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Biotin_lipoyl PF00364.22 GAN11480.1 - 3.6e-19 68.4 0.2 1.1e-18 66.8 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GAN11480.1 - 2.6e-07 30.9 0.2 7.1e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain 2-oxoacid_dh PF00198.23 GAN11480.1 - 0.0038 16.7 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl_2 PF13533.6 GAN11480.1 - 0.005 16.6 0.1 0.035 13.9 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like RE_HaeIII PF09556.10 GAN11480.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 HaeIII restriction endonuclease QRPTase_N PF02749.16 GAN11480.1 - 0.17 12.0 0.0 0.53 10.4 0.0 1.9 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain FlxA PF14282.6 GAN11481.1 - 0.45 10.5 0.0 0.19 11.8 4.8 5.6 4 1 0 5 5 5 0 FlxA-like protein PRIMA1 PF16101.5 GAN11481.1 - 8.8 6.4 7.9 11 6.0 6.7 2.0 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 F-box-like PF12937.7 GAN11482.1 - 0.0013 18.6 0.7 0.0097 15.8 0.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 GAN11482.1 - 0.004 17.1 0.6 42 4.5 0.1 4.9 4 0 0 4 4 4 1 Leucine Rich repeat tRNA-synt_1g PF09334.11 GAN11483.1 - 1.1e-100 337.2 0.6 4.2e-100 335.3 0.6 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAN11483.1 - 8.2e-25 87.1 5.9 3e-12 45.6 0.3 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GAN11483.1 - 1.5e-12 47.5 0.3 3.5e-07 29.9 0.4 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 GAN11483.1 - 6e-05 23.0 0.1 0.00013 21.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA MT0933_antitox PF14013.6 GAN11483.1 - 0.071 13.4 0.6 0.29 11.5 0.1 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein RVT_1 PF00078.27 GAN11484.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HLH PF00010.26 GAN11485.1 - 1.1e-08 34.9 1.0 2.5e-08 33.8 1.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_15 PF00723.21 GAN11486.1 - 9.7e-59 199.3 0.0 2.3e-57 194.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 FAA_hydrolase PF01557.18 GAN11486.1 - 6.8e-10 39.0 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family EB1 PF03271.17 GAN11488.1 - 1.3e-16 60.5 0.3 3e-16 59.4 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GAN11488.1 - 7.7e-06 26.0 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 GAN11488.1 - 0.0053 15.3 0.0 0.0074 14.9 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like ING PF12998.7 GAN11488.1 - 0.075 13.6 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-C4H2 PF10146.9 GAN11488.1 - 0.12 12.7 0.8 0.2 11.9 0.8 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Bromodomain PF00439.25 GAN11489.1 - 2.3e-47 159.0 2.1 3.2e-24 84.8 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 GAN11489.1 - 2.3e-22 78.9 0.2 9.2e-22 77.0 0.2 2.2 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Csm1_N PF18504.1 GAN11489.1 - 0.18 12.2 8.1 0.71 10.3 1.9 3.0 2 0 0 2 2 2 0 Csm1 N-terminal domain End3 PF12761.7 GAN11489.1 - 0.59 10.3 12.9 3.2 7.9 4.5 2.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 SlyX PF04102.12 GAN11489.1 - 0.98 10.1 3.8 14 6.3 0.5 3.3 2 0 0 2 2 2 0 SlyX DUF2802 PF10975.8 GAN11489.1 - 1.2 9.3 4.6 12 6.1 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) GCD14 PF08704.10 GAN11491.1 - 2.1e-20 73.4 0.0 3.7e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 GAN11491.1 - 3.3e-06 27.0 0.0 5.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN11491.1 - 7.4e-06 26.6 0.0 1.5e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAN11491.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 GAN11491.1 - 0.0026 18.8 0.0 0.0044 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN11491.1 - 0.0037 17.1 0.0 0.0069 16.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAN11491.1 - 0.04 13.2 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 GAN11491.1 - 0.15 12.7 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HSP70 PF00012.20 GAN11493.1 - 3.6e-118 395.4 1.3 4e-118 395.2 1.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAN11493.1 - 1.6e-12 46.9 0.4 7.3e-11 41.5 0.2 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Asp_decarbox PF02261.16 GAN11493.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Aspartate decarboxylase PEARLI-4 PF05278.12 GAN11493.1 - 0.031 13.9 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Hydantoinase_A PF01968.18 GAN11493.1 - 0.043 13.1 1.0 0.048 12.9 0.2 1.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.10 GAN11493.1 - 0.045 12.7 0.5 0.09 11.7 0.2 1.6 1 1 1 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Sds3 PF08598.11 GAN11494.1 - 1.5e-08 34.9 9.8 1.5e-08 34.9 9.8 2.4 2 1 0 2 2 2 1 Sds3-like DUF4949 PF16307.5 GAN11494.1 - 0.23 11.6 1.1 0.84 9.8 0.2 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4949) DUF702 PF05142.12 GAN11494.1 - 0.43 11.1 10.6 0.13 12.8 6.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Ndc1_Nup PF09531.10 GAN11494.1 - 0.53 8.9 8.9 0.66 8.6 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3112 PF11309.8 GAN11494.1 - 1 8.8 2.8 2.3 7.6 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Folate_carrier PF01770.18 GAN11494.1 - 1.3 7.7 4.1 1.9 7.1 4.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 GAN11494.1 - 1.5 7.0 5.7 2.9 6.1 5.4 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.15 GAN11494.1 - 1.5 7.6 5.1 2.2 7.1 5.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) YfhO PF09586.10 GAN11494.1 - 9.2 4.4 10.2 15 3.6 10.2 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO HAD PF12710.7 GAN11495.1 - 2.1e-19 70.7 0.1 2.6e-19 70.4 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAN11495.1 - 0.0013 19.1 0.1 0.0046 17.3 0.0 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Peripla_BP_6 PF13458.6 GAN11495.1 - 0.0066 16.1 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein PMT PF02366.18 GAN11497.1 - 1.3e-43 149.3 8.3 3e-43 148.2 8.3 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 GAN11497.1 - 1.1e-17 64.5 2.6 2.3e-17 63.5 2.6 1.4 1 0 0 1 1 1 1 MIR domain PMT_4TMC PF16192.5 GAN11497.1 - 4.8e-06 26.3 3.9 1.4e-05 24.8 3.9 1.8 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 GAN11497.1 - 0.0063 16.7 5.1 0.0063 16.7 5.1 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ERG2_Sigma1R PF04622.12 GAN11498.1 - 1.5e-90 302.2 0.8 1.7e-90 302.0 0.8 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein RVT_1 PF00078.27 GAN11500.1 - 1.1e-05 25.1 0.0 1.1e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) bZIP_1 PF00170.21 GAN11501.1 - 2.2e-08 34.1 13.9 2.2e-08 34.1 13.9 2.8 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 GAN11501.1 - 4.9e-07 29.7 19.4 1.6e-05 24.8 8.8 2.9 1 1 1 2 2 2 2 Basic region leucine zipper Shugoshin_N PF07558.11 GAN11501.1 - 0.0036 17.1 3.4 0.0089 15.9 3.4 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF4988 PF16378.5 GAN11501.1 - 0.048 13.3 1.8 0.087 12.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function HD_3 PF13023.6 GAN11501.1 - 0.053 13.4 4.9 0.15 12.0 4.9 1.7 1 0 0 1 1 1 0 HD domain UPF0242 PF06785.11 GAN11501.1 - 0.056 13.6 10.5 0.16 12.1 10.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_Maf PF03131.17 GAN11501.1 - 0.084 13.4 10.1 0.49 10.9 10.0 2.4 1 1 0 1 1 1 0 bZIP Maf transcription factor EMC3_TMCO1 PF01956.16 GAN11501.1 - 1.3 8.8 3.4 6.2 6.5 3.4 2.0 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spc24 PF08286.11 GAN11501.1 - 1.5 9.1 9.1 0.55 10.5 5.1 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ABC2_membrane_3 PF12698.7 GAN11501.1 - 2.1 7.4 7.0 0.095 11.8 0.6 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein YabA PF06156.13 GAN11501.1 - 3.4 8.4 10.7 4.7 7.9 8.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Methyltransf_31 PF13847.6 GAN11502.1 - 4.5e-19 68.7 0.0 6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAN11502.1 - 8.1e-10 39.3 0.0 2.1e-09 38.0 0.0 1.8 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAN11502.1 - 1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN11502.1 - 1.9e-08 35.0 0.0 5.3e-08 33.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN11502.1 - 6.7e-08 33.1 0.0 2.7e-07 31.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAN11502.1 - 5.8e-07 29.2 0.0 8.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 GAN11502.1 - 2e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 GAN11502.1 - 4.5e-05 23.5 0.0 7.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 GAN11502.1 - 0.00016 22.0 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 GAN11502.1 - 0.00047 19.7 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 GAN11502.1 - 0.00057 19.4 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 GAN11502.1 - 0.00095 18.9 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) tRNA_U5-meth_tr PF05958.11 GAN11502.1 - 0.0021 17.1 0.0 0.0048 15.9 0.0 1.5 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase DOT1 PF08123.13 GAN11502.1 - 0.0053 16.3 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 GAN11502.1 - 0.0097 15.4 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.11 GAN11502.1 - 0.017 14.0 0.1 0.091 11.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 GAN11502.1 - 0.056 13.4 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 GAN11502.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase AAA PF00004.29 GAN11503.1 - 8e-23 81.3 0.0 2.3e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 GAN11503.1 - 2.1e-11 44.2 0.6 3.8e-11 43.3 0.6 1.4 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.12 GAN11503.1 - 4.4e-07 29.8 0.0 8.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAN11503.1 - 8.1e-05 23.1 0.0 0.00079 19.8 0.0 2.1 2 1 1 3 3 2 1 AAA ATPase domain AAA_7 PF12775.7 GAN11503.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 GAN11503.1 - 0.00024 21.0 0.5 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAN11503.1 - 0.00026 21.0 0.0 0.00079 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAN11503.1 - 0.00035 21.1 0.0 0.0017 18.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAN11503.1 - 0.00046 20.5 1.6 0.028 14.7 0.0 3.0 3 1 1 4 4 2 1 AAA domain DUF815 PF05673.13 GAN11503.1 - 0.00079 18.7 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAN11503.1 - 0.003 17.9 0.1 0.029 14.8 0.0 2.6 2 1 0 2 2 2 1 RNA helicase ATPase PF06745.13 GAN11503.1 - 0.0039 16.6 0.1 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.17 GAN11503.1 - 0.0051 16.0 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 GAN11503.1 - 0.0056 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAN11503.1 - 0.0073 16.7 0.3 0.048 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAN11503.1 - 0.01 16.4 0.7 0.037 14.5 0.1 2.2 2 1 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 GAN11503.1 - 0.012 15.8 0.3 0.062 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 GAN11503.1 - 0.013 13.5 0.0 0.019 12.9 0.0 1.3 1 0 0 1 1 1 0 Helicase ResIII PF04851.15 GAN11503.1 - 0.028 14.4 1.7 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAN11503.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_34 PF13872.6 GAN11503.1 - 0.037 12.9 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 AAA_24 PF13479.6 GAN11503.1 - 0.038 13.7 1.9 0.18 11.5 0.2 2.8 2 2 1 3 3 3 0 AAA domain TsaE PF02367.17 GAN11503.1 - 0.094 12.7 0.0 0.95 9.5 0.0 2.5 1 1 2 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mur_ligase_M PF08245.12 GAN11503.1 - 0.11 12.5 0.5 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Mur ligase middle domain AAA_25 PF13481.6 GAN11503.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 GAN11503.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Kinesin PF00225.23 GAN11504.1 - 2.6e-92 309.3 0.2 2.6e-92 309.3 0.2 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAN11504.1 - 1.8e-14 53.9 0.0 1.9e-13 50.6 0.0 2.6 1 1 0 1 1 1 1 Microtubule binding PriC PF07445.12 GAN11504.1 - 0.016 15.2 17.6 0.6 10.0 0.1 2.8 2 0 0 2 2 2 0 Primosomal replication protein priC bZIP_2 PF07716.15 GAN11504.1 - 5.2 7.2 9.8 6.3 7.0 0.0 3.9 3 0 0 3 3 3 0 Basic region leucine zipper YabA PF06156.13 GAN11504.1 - 8.3 7.1 17.4 0.41 11.3 4.2 3.9 3 1 1 4 4 4 0 Initiation control protein YabA FYVE PF01363.21 GAN11506.1 - 1.9e-08 34.3 0.1 1.9e-08 34.3 0.1 2.2 2 1 0 2 2 2 1 FYVE zinc finger Arm PF00514.23 GAN11506.1 - 0.00015 21.7 3.5 16 5.7 0.0 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat RVT_1 PF00078.27 GAN11507.1 - 8.8e-31 107.1 0.0 2.3e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 GAN11507.1 - 3.7e-08 34.0 4.2 1.4e-07 32.1 4.2 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GAN11507.1 - 3.6e-07 30.0 6.6 5.8e-07 29.4 0.1 3.3 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase GST_N_3 PF13417.6 GAN11508.1 - 4.7e-14 52.5 0.0 9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAN11508.1 - 1.4e-11 44.5 0.0 2.1e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAN11508.1 - 2.8e-07 30.7 0.0 5.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Gly_transf_sug PF04488.15 GAN11509.1 - 0.00017 22.2 0.0 0.00037 21.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SpoVAB PF13782.6 GAN11510.1 - 0.56 10.5 5.3 3.8 7.9 4.7 2.3 2 1 0 2 2 2 0 Stage V sporulation protein AB VTC PF09359.10 GAN11511.1 - 1.2e-81 274.1 0.7 1.2e-81 274.1 0.7 1.9 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAN11511.1 - 5.4e-12 46.0 3.1 5.4e-12 46.0 3.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAN11511.1 - 8.8e-09 35.7 17.4 2e-06 28.0 6.2 3.3 2 1 1 3 3 3 2 SPX domain MscS_TM PF12794.7 GAN11511.1 - 0.0096 14.8 1.1 0.014 14.2 1.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 THOC7 PF05615.13 GAN11511.1 - 0.09 13.1 2.0 0.29 11.4 1.1 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Voltage_CLC PF00654.20 GAN11512.1 - 2.5e-87 293.4 24.1 2.5e-87 293.4 24.1 2.5 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAN11512.1 - 7.5e-05 23.1 0.0 0.0005 20.5 0.0 2.4 2 0 0 2 2 2 1 CBS domain RT_RNaseH_2 PF17919.1 GAN11513.1 - 1.2e-35 121.5 0.0 2.5e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAN11513.1 - 1.1e-34 118.8 0.0 2.4e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAN11513.1 - 5.8e-22 78.3 0.6 1.6e-21 76.8 0.2 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAN11513.1 - 2.3e-16 59.7 0.7 1.4e-15 57.1 0.6 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 GAN11513.1 - 2.4e-16 59.8 1.2 3.4e-15 56.1 0.1 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 GAN11513.1 - 1e-07 32.4 0.0 2.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAN11513.1 - 8.6e-07 29.5 0.0 1.7e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 GAN11513.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 GAN11513.1 - 0.035 14.4 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC PF00098.23 GAN11513.1 - 0.17 12.0 7.6 0.034 14.2 3.3 2.1 2 0 0 2 2 2 0 Zinc knuckle Asp_protease PF09668.10 GAN11513.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Phos_pyr_kin PF08543.12 GAN11514.1 - 3.3e-86 288.7 2.6 4.6e-86 288.2 2.6 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 GAN11514.1 - 8.9e-42 143.3 0.0 1.4e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 GAN11514.1 - 1.6e-06 27.6 0.3 2.9e-06 26.8 0.3 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 GAN11514.1 - 0.00076 19.0 0.1 0.0014 18.1 0.1 1.5 1 1 0 1 1 1 1 Carbohydrate kinase LcrV PF04792.12 GAN11514.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein DEAD PF00270.29 GAN11515.1 - 2e-48 164.5 0.8 4.5e-48 163.3 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN11515.1 - 7.3e-25 87.5 0.1 3.5e-24 85.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAN11515.1 - 3.3e-20 72.1 0.5 7e-20 71.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 GAN11515.1 - 3.7e-05 23.1 0.0 7.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAN11515.1 - 4e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RVT PF13966.6 GAN11516.1 - 9.9e-05 23.0 0.6 9.9e-05 23.0 0.6 2.2 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase HDAC4_Gln PF12203.8 GAN11516.1 - 0.35 11.1 5.8 0.63 10.2 4.5 1.8 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 HEAT_EZ PF13513.6 GAN11517.1 - 1.7e-28 98.6 12.5 1e-13 51.5 0.0 9.7 7 2 3 10 10 10 5 HEAT-like repeat HEAT PF02985.22 GAN11517.1 - 6.2e-20 69.6 9.2 0.00015 21.7 0.0 9.5 9 0 0 9 9 9 4 HEAT repeat IBN_N PF03810.19 GAN11517.1 - 2.6e-14 52.9 0.0 1.4e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 GAN11517.1 - 1.2e-13 51.3 0.7 0.001 19.4 0.0 6.4 4 3 1 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GAN11517.1 - 4.2e-09 36.9 0.0 0.054 14.1 0.0 5.1 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAN11517.1 - 2.9e-07 30.7 1.7 2.5 8.1 0.1 4.5 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAN11517.1 - 0.0002 21.3 11.8 0.55 10.3 0.1 6.3 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 GAN11517.1 - 0.00043 19.0 0.1 1.5 7.3 0.0 3.1 2 1 0 2 2 2 2 Adaptin N terminal region TAF6_C PF07571.13 GAN11517.1 - 0.00067 19.9 0.0 1 9.8 0.0 4.3 4 0 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain TIP120 PF08623.10 GAN11517.1 - 0.012 15.4 0.0 2.3 7.9 0.0 3.5 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) MMS19_C PF12460.8 GAN11517.1 - 0.032 13.4 2.6 12 4.9 0.0 4.1 3 2 1 4 4 4 0 RNAPII transcription regulator C-terminal ParcG PF10274.9 GAN11517.1 - 0.035 14.2 0.2 33 4.5 0.1 3.9 4 0 0 4 4 4 0 Parkin co-regulated protein PX PF00787.24 GAN11518.1 - 2.8e-15 56.3 0.3 5.2e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.19 GAN11518.1 - 0.0013 18.6 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 SNARE domain HLH PF00010.26 GAN11519.1 - 1.5e-12 47.3 0.7 3.3e-12 46.2 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YabA PF06156.13 GAN11519.1 - 3 8.5 12.2 2.8 8.7 1.7 2.7 2 1 1 3 3 3 0 Initiation control protein YabA Na_Ca_ex_C PF16494.5 GAN11519.1 - 7.1 7.1 11.0 2.3 8.7 4.6 2.3 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Apq12 PF12716.7 GAN11520.1 - 0.38 10.7 10.1 0.62 10.0 10.1 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis UPF0561 PF10573.9 GAN11521.1 - 0.01 16.0 0.1 5 7.3 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Phage_int_SAM_1 PF02899.17 GAN11521.1 - 0.082 13.2 0.1 0.082 13.2 0.1 3.5 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain Arrestin_C PF02752.22 GAN11522.1 - 8.4e-16 58.7 5.7 1.5e-09 38.4 1.9 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAN11522.1 - 3.2e-13 49.9 0.2 1.1e-10 41.7 0.0 3.0 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAN11522.1 - 7.9e-05 22.4 0.1 0.00028 20.6 0.1 2.0 1 1 1 2 2 2 1 Arrestin_N terminal like Cwf_Cwc_15 PF04889.12 GAN11522.1 - 0.014 15.1 8.8 0.25 11.0 0.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 GAN11522.1 - 0.76 8.3 16.2 0.45 9.0 4.7 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 GAN11522.1 - 4.5 7.3 13.4 3.2 7.8 2.0 2.3 2 0 0 2 2 2 0 YL1 nuclear protein COPI_assoc PF08507.10 GAN11523.1 - 0.0057 16.7 2.1 0.0057 16.7 2.1 1.8 1 1 1 2 2 2 1 COPI associated protein Sugar_tr PF00083.24 GAN11524.1 - 7.6e-54 183.3 21.7 9.5e-54 183.0 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN11524.1 - 6.4e-22 78.0 33.4 2.2e-13 49.9 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 GAN11524.1 - 0.019 14.6 2.8 2.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) YopX PF09643.10 GAN11528.1 - 1.5e-20 73.6 2.1 7.1e-20 71.4 2.1 2.1 1 1 0 1 1 1 1 YopX protein TF_Zn_Ribbon PF08271.12 GAN11528.1 - 0.0019 17.7 2.0 0.0027 17.2 0.7 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 GAN11528.1 - 0.023 14.1 1.0 0.72 9.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 GAN11528.1 - 0.026 14.9 0.5 0.063 13.7 0.2 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF2387 PF09526.10 GAN11528.1 - 0.044 13.9 2.3 0.081 13.1 0.6 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc_ribbon_2 PF13240.6 GAN11528.1 - 0.051 13.3 0.8 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 GAN11528.1 - 0.062 13.2 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 GAN11528.1 - 0.17 12.0 1.9 1.3 9.2 1.7 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 GAN11528.1 - 0.26 11.6 1.8 1.8 8.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-CHCC PF10276.9 GAN11528.1 - 0.32 11.1 3.1 1.7 8.8 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger domain A2L_zn_ribbon PF08792.10 GAN11528.1 - 0.66 9.8 2.5 2.2 8.1 0.3 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF668 PF05003.12 GAN11530.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF668) YcbB PF08664.10 GAN11530.1 - 0.055 13.5 0.1 0.068 13.2 0.1 1.1 1 0 0 1 1 1 0 YcbB domain FTCD_C PF04961.12 GAN11530.1 - 0.67 9.7 4.9 3.5 7.4 1.7 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Say1_Mug180 PF10340.9 GAN11532.1 - 0.021 13.7 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase HSF_DNA-bind PF00447.17 GAN11536.1 - 1.3e-33 115.5 1.0 3.4e-33 114.1 1.0 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding XPC-binding PF09280.11 GAN11536.1 - 0.037 13.8 1.4 0.037 13.8 1.4 2.4 2 0 0 2 2 2 0 XPC-binding domain DUF3135 PF11333.8 GAN11536.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Ribosomal_L11 PF00298.19 GAN11536.1 - 0.079 13.5 0.1 0.21 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain SAS4 PF15460.6 GAN11537.1 - 0.00063 19.8 16.1 0.0022 18.0 14.9 2.2 1 1 1 2 2 2 1 Something about silencing, SAS, complex subunit 4 BET PF17035.5 GAN11537.1 - 0.11 12.7 3.0 0.078 13.2 1.1 1.9 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation PEHE PF15275.6 GAN11537.1 - 0.94 10.1 12.5 3.8 8.2 12.5 2.1 1 1 0 1 1 1 0 PEHE domain cNMP_binding PF00027.29 GAN11538.1 - 4.1e-37 126.1 0.0 3.9e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_4 PF12799.7 GAN11538.1 - 2.6e-17 62.6 10.7 0.00053 20.3 0.0 6.8 7 0 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAN11538.1 - 8.4e-15 53.5 11.6 0.65 10.2 0.3 10.0 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 GAN11538.1 - 2.9e-06 27.1 22.6 8.3 7.4 0.3 10.0 9 1 0 9 9 9 2 Leucine Rich Repeat F-box PF00646.33 GAN11538.1 - 9.3e-06 25.4 1.7 2.6e-05 23.9 0.1 2.6 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAN11538.1 - 0.0027 17.6 0.2 0.017 15.0 0.2 2.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 GAN11538.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.8 3 0 0 3 3 3 0 F-box-like CopG_antitoxin PF12441.8 GAN11538.1 - 0.033 14.7 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system LRR_8 PF13855.6 GAN11538.1 - 0.26 11.1 17.1 13 5.7 0.3 6.5 3 1 4 7 7 7 0 Leucine rich repeat Septin PF00735.18 GAN11540.1 - 1.1e-109 366.1 1.2 1.8e-109 365.4 1.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAN11540.1 - 1.3e-07 31.7 0.0 3.8e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAN11540.1 - 2.9e-06 27.3 2.3 1e-05 25.5 0.7 2.5 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAN11540.1 - 4.2e-06 26.4 6.2 4.4e-05 23.1 0.1 3.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAN11540.1 - 0.00015 22.0 0.2 0.00045 20.4 0.2 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAN11540.1 - 0.001 19.3 0.2 0.004 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 GAN11540.1 - 0.0055 16.0 0.2 0.014 14.7 0.2 1.7 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 GAN11540.1 - 0.006 16.0 0.4 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAN11540.1 - 0.0074 16.7 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Ras PF00071.22 GAN11540.1 - 0.0085 15.7 0.1 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.6 GAN11540.1 - 0.0087 16.5 0.6 0.027 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 GAN11540.1 - 0.011 15.4 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 GAN11540.1 - 0.013 15.3 0.3 0.027 14.2 0.3 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAN11540.1 - 0.013 15.5 7.6 2.5 8.2 0.0 3.4 2 1 1 3 3 3 0 Dynamin family AAA_7 PF12775.7 GAN11540.1 - 0.017 14.6 0.5 0.032 13.8 0.5 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAN11540.1 - 0.019 14.9 1.7 0.76 9.7 0.3 2.7 2 1 0 2 2 2 0 NTPase Pox_A32 PF04665.12 GAN11540.1 - 0.02 14.4 0.1 0.055 12.9 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein T2SSE PF00437.20 GAN11540.1 - 0.03 13.4 0.3 0.053 12.6 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAN11540.1 - 0.034 14.7 0.7 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 GAN11540.1 - 0.044 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CCDC-167 PF15188.6 GAN11540.1 - 0.068 13.5 3.4 0.19 12.1 3.4 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 AAA_33 PF13671.6 GAN11540.1 - 0.081 13.1 3.3 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF29 PF01724.16 GAN11540.1 - 0.082 13.1 4.3 0.071 13.3 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF29 NACHT PF05729.12 GAN11540.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 GAN11540.1 - 0.11 12.2 1.8 3.2 7.5 0.1 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 GAN11540.1 - 0.14 11.9 1.3 1.7 8.4 0.1 3.0 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 GAN11540.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FOXP-CC PF16159.5 GAN11540.1 - 0.19 12.4 2.0 0.45 11.2 0.6 2.4 2 1 0 2 2 1 0 FOXP coiled-coil domain AAA_18 PF13238.6 GAN11540.1 - 0.2 12.2 1.6 0.56 10.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain Exonuc_VII_L PF02601.15 GAN11540.1 - 0.21 11.1 2.4 0.32 10.5 2.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRK PF00485.18 GAN11540.1 - 0.22 11.2 3.4 0.39 10.4 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 GAN11540.1 - 0.29 11.6 16.4 0.33 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain APG6_N PF17675.1 GAN11540.1 - 0.36 11.4 12.5 0.76 10.3 12.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF16 PF01519.16 GAN11540.1 - 1.9 9.0 9.0 0.38 11.3 3.4 2.6 3 0 0 3 3 2 0 Protein of unknown function DUF16 RVT_1 PF00078.27 GAN11541.1 - 3.7e-34 118.2 0.1 5.3e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_Tnp_IS1595 PF12760.7 GAN11542.1 - 0.00093 19.1 3.1 0.18 11.8 0.3 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 GAN11542.1 - 0.016 15.5 0.5 0.19 12.2 0.1 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-Di19 PF05605.12 GAN11542.1 - 0.14 12.5 1.4 2.1 8.7 0.0 3.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_2 PF13240.6 GAN11542.1 - 0.17 11.7 2.6 0.45 10.3 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC PF00098.23 GAN11542.1 - 2.5 8.3 6.7 0.28 11.3 0.6 2.5 3 0 0 3 3 3 0 Zinc knuckle Herpes_Helicase PF02689.14 GAN11543.1 - 0.0013 16.8 0.0 0.0013 16.7 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 GAN11543.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RNB PF00773.19 GAN11544.1 - 2.5e-76 257.1 0.2 2.5e-76 257.1 0.2 1.9 3 0 0 3 3 3 1 RNB domain OB_Dis3 PF17849.1 GAN11544.1 - 7.1e-22 77.2 0.0 1.6e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 GAN11544.1 - 3.3e-15 56.2 0.1 1.9e-13 50.6 0.0 3.4 3 0 0 3 3 3 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 GAN11544.1 - 0.0077 15.9 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease B OB domain NDC10_II PF16787.5 GAN11545.1 - 0.0012 17.9 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 UDPGT PF00201.18 GAN11546.1 - 2e-27 96.2 0.6 9.8e-27 93.9 0.6 2.2 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAN11546.1 - 0.032 14.2 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DNA_pol_B_exo1 PF03104.19 GAN11546.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain RT_RNaseH_2 PF17919.1 GAN11547.1 - 1.4e-27 95.6 0.1 5e-27 93.9 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAN11547.1 - 5.3e-20 71.7 0.1 1.6e-19 70.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAN11547.1 - 2e-14 53.7 1.4 3.5e-14 52.9 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAN11547.1 - 1.9e-12 47.4 0.0 5.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GAN11547.1 - 1.6e-10 40.9 0.2 5.5e-10 39.2 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GAN11547.1 - 8.9e-10 38.3 0.7 2.5e-09 36.9 0.4 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 GAN11547.1 - 0.0081 16.4 0.4 0.021 15.0 0.4 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Tudor-knot PF11717.8 GAN11547.1 - 0.014 15.3 0.2 0.28 11.1 0.1 2.7 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Peptidase_A17 PF05380.13 GAN11547.1 - 0.11 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Pao retrotransposon peptidase RT_RNaseH PF17917.1 GAN11549.1 - 4.6e-23 81.5 0.1 6.3e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN11549.1 - 1.3e-19 70.1 0.1 3.8e-18 65.4 0.1 2.3 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rho_GDI PF02115.17 GAN11550.1 - 2.2e-70 236.4 1.3 2.6e-70 236.1 1.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor SH3_1 PF00018.28 GAN11551.1 - 8.2e-24 83.0 0.0 2.4e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 GAN11551.1 - 5.4e-14 51.8 0.0 2.2e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 GAN11551.1 - 1.1e-09 37.8 0.0 1.8e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 GAN11551.1 - 1.3e-08 34.8 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PX domain FOG_N PF15888.5 GAN11551.1 - 1 9.7 3.9 7.4 7.0 0.0 3.4 4 0 0 4 4 4 0 Folded gastrulation N-terminus Lactonase PF10282.9 GAN11552.1 - 1.9e-107 359.5 0.3 2.2e-107 359.3 0.3 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 GAN11552.1 - 0.05 12.7 0.1 0.21 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) HNH_3 PF13392.6 GAN11554.1 - 9.8e-08 31.6 0.2 2e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF550 PF04447.12 GAN11554.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF550) RecT PF03837.14 GAN11555.1 - 1.5e-63 213.9 0.0 2.5e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 RecT family YqaJ PF09588.10 GAN11555.1 - 1.1e-28 100.3 0.0 2.6e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain DUF3887 PF13026.6 GAN11555.1 - 0.26 12.1 3.6 3.6 8.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) DDE_3 PF13358.6 GAN11558.1 - 3.3e-13 49.6 0.1 4.9e-11 42.6 0.1 2.1 1 1 0 2 2 2 2 DDE superfamily endonuclease CDP-OH_P_transf PF01066.21 GAN11559.1 - 6.9e-18 65.2 0.1 6.9e-18 65.2 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DDE_3 PF13358.6 GAN11561.1 - 5.8e-05 22.9 0.3 5.8e-05 22.9 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease VTC PF09359.10 GAN11565.1 - 1e-76 258.0 0.0 1.7e-76 257.3 0.0 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 GAN11565.1 - 8.9e-13 48.5 2.6 8.9e-13 48.5 2.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAN11565.1 - 9.9e-11 42.2 6.3 3.3e-08 33.9 0.1 2.8 2 1 1 3 3 3 2 SPX domain MFS_1 PF07690.16 GAN11566.1 - 1.4e-44 152.5 19.0 1.4e-44 152.5 19.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAN11566.1 - 1.2e-05 24.8 20.6 5.1e-05 22.7 15.5 2.6 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4199 PF13858.6 GAN11566.1 - 0.028 14.8 13.1 0.93 9.9 0.0 4.0 3 1 0 4 4 4 0 Protein of unknown function (DUF4199) Beta-lactamase2 PF13354.6 GAN11567.1 - 1.1e-34 119.9 0.1 1.2e-34 119.8 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 GAN11567.1 - 5.7e-24 85.0 0.0 1.2e-23 83.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 GAN11567.1 - 0.014 14.8 0.0 0.053 12.9 0.0 1.6 1 1 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase SH3_1 PF00018.28 GAN11568.1 - 1.1e-14 53.8 0.4 1.8e-14 53.0 0.4 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAN11568.1 - 2e-11 43.5 0.3 3.7e-11 42.7 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAN11568.1 - 1.1e-10 41.0 0.0 2.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 GAN11568.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 WW domain Pyridoxal_deC PF00282.19 GAN11569.1 - 1e-77 261.4 0.0 1.3e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAN11569.1 - 1.4e-06 27.5 0.0 9e-06 24.9 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAN11569.1 - 0.00097 18.5 0.0 0.0016 17.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.18 GAN11570.1 - 6.2e-27 94.3 0.2 6.2e-27 94.3 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAM176 PF14851.6 GAN11570.1 - 1.2 8.8 9.1 2.7 7.6 9.1 1.6 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 GAN11570.1 - 1.9 8.5 11.4 4.5 7.3 11.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal PI3K_1B_p101 PF10486.9 GAN11570.1 - 4 5.1 7.1 6.7 4.4 7.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 GAN11570.1 - 7 4.6 23.3 12 3.9 23.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAN11570.1 - 7.1 4.7 17.7 13 3.9 17.7 1.3 1 0 0 1 1 1 0 Nop14-like family Hat1_N PF10394.9 GAN11571.1 - 4.9e-38 130.9 0.2 5.6e-38 130.7 0.2 1.0 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Haemadin PF09065.10 GAN11571.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Haemadin Acyl-CoA_dh_1 PF00441.24 GAN11572.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HAMP PF00672.25 GAN11573.1 - 4.1e-33 113.5 9.8 1.2e-09 38.4 0.1 5.4 5 0 0 5 5 5 4 HAMP domain HATPase_c PF02518.26 GAN11573.1 - 3.1e-31 108.2 0.1 7.6e-31 106.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAN11573.1 - 1.5e-27 95.9 3.9 1.5e-26 92.8 0.3 3.6 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 GAN11573.1 - 4.4e-17 61.9 3.9 8e-17 61.0 0.5 3.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain WXG100 PF06013.12 GAN11573.1 - 0.00018 21.7 10.5 0.058 13.6 0.1 5.2 4 2 1 5 5 5 1 Proteins of 100 residues with WXG HTH_6 PF01418.17 GAN11573.1 - 0.0026 17.7 0.1 14 5.8 0.0 4.8 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family DUF948 PF06103.11 GAN11573.1 - 0.0037 17.5 31.3 1.2 9.5 2.3 7.1 2 1 3 5 5 5 3 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 GAN11573.1 - 0.011 15.9 18.0 0.06 13.4 2.7 4.7 1 1 5 6 6 6 0 Apolipophorin-III precursor (apoLp-III) DUF1759 PF03564.15 GAN11573.1 - 0.02 14.9 3.8 27 4.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1759) DUF4279 PF14106.6 GAN11573.1 - 0.021 15.0 0.0 5.5 7.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) FleQ PF06490.11 GAN11573.1 - 0.033 14.6 0.2 0.15 12.4 0.0 2.3 2 0 0 2 2 1 0 Flagellar regulatory protein FleQ Jnk-SapK_ap_N PF09744.9 GAN11573.1 - 0.041 14.1 1.2 0.14 12.4 0.1 2.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 VHS PF00790.19 GAN11573.1 - 0.048 13.5 0.3 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 VHS domain DUF3626 PF12294.8 GAN11573.1 - 0.05 12.7 1.2 0.11 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3626) Baculo_PEP_C PF04513.12 GAN11573.1 - 0.14 12.2 27.0 6 6.9 10.7 5.3 2 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4731 PF15875.5 GAN11573.1 - 0.14 12.3 3.4 29 4.9 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4731) GLE1 PF07817.13 GAN11573.1 - 0.29 10.3 2.8 6.8 5.8 0.1 3.4 2 1 2 4 4 4 0 GLE1-like protein Zw10 PF06248.13 GAN11573.1 - 0.43 9.1 7.5 0.82 8.2 1.0 2.5 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 CENP-F_leu_zip PF10473.9 GAN11573.1 - 4.1 7.4 11.6 15 5.6 0.2 4.3 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_hydro_18 PF00704.28 GAN11575.1 - 6.1e-89 298.8 1.4 7.1e-89 298.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sel1 PF08238.12 GAN11577.1 - 6.9e-15 55.2 3.2 7.8e-08 32.7 0.1 4.7 5 0 0 5 5 5 3 Sel1 repeat DUF1727 PF08353.10 GAN11577.1 - 0.0013 18.6 0.1 0.0034 17.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1727) TPR_2 PF07719.17 GAN11577.1 - 0.074 13.2 1.3 7.4 7.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 GAN11578.1 - 5.8e-39 131.4 23.0 8.9e-07 29.5 1.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.12 GAN11578.1 - 8.2e-23 80.7 0.4 1.8e-22 79.6 0.4 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 GAN11578.1 - 6.9e-08 32.7 2.5 0.011 16.0 0.3 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAN11578.1 - 0.002 16.9 9.5 0.65 8.6 0.3 4.8 1 1 3 5 5 5 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAN11578.1 - 0.012 15.6 0.1 8.5 6.5 0.1 4.1 3 1 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Ig_GlcNase PF18368.1 GAN11578.1 - 0.091 12.9 0.9 4.6 7.5 0.0 3.1 3 0 0 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain PQQ_3 PF13570.6 GAN11578.1 - 0.57 10.7 4.8 10 6.7 0.2 4.4 5 0 0 5 5 5 0 PQQ-like domain Malic_M PF03949.15 GAN11579.1 - 3.1e-91 305.2 0.0 5e-91 304.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAN11579.1 - 1e-71 240.5 0.0 1.9e-71 239.6 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Whi5 PF08528.11 GAN11580.1 - 0.00099 18.7 0.2 0.0017 17.9 0.2 1.4 1 0 0 1 1 1 1 Whi5 like Methyltransf_31 PF13847.6 GAN11581.1 - 2.3e-12 47.0 0.0 4.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAN11581.1 - 1.5e-10 40.9 0.1 3.8e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAN11581.1 - 1.5e-09 38.5 0.0 3.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAN11581.1 - 4.4e-08 33.8 0.0 1.1e-07 32.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAN11581.1 - 2.6e-07 30.5 0.1 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 GAN11581.1 - 6e-07 29.1 0.3 1.3e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 GAN11581.1 - 3.9e-05 23.1 0.0 7.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_23 PF13489.6 GAN11581.1 - 0.00026 20.8 0.0 0.00063 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PseudoU_synth_2 PF00849.22 GAN11581.1 - 0.00033 20.8 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase Methyltransf_18 PF12847.7 GAN11581.1 - 0.00042 20.3 0.6 0.00089 19.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN11581.1 - 0.00091 19.8 0.0 0.0024 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAN11581.1 - 0.0032 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 GAN11581.1 - 0.0045 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ub-Mut7C PF14451.6 GAN11581.1 - 0.096 12.5 0.2 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Mut7-C ubiquitin Pkinase PF00069.25 GAN11582.1 - 6.8e-58 196.1 0.0 1.1e-57 195.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11582.1 - 4.1e-24 85.3 0.0 6.8e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN11582.1 - 5.2e-06 26.0 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAN11582.1 - 0.0002 20.3 0.0 0.0002 20.3 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAN11582.1 - 0.0049 16.2 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAN11582.1 - 0.034 14.1 0.4 0.1 12.5 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family LIM_bind PF01803.16 GAN11583.1 - 0.014 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 LIM-domain binding protein CBFB_NFYA PF02045.15 GAN11584.1 - 5e-29 100.7 6.5 8.2e-29 100.0 6.5 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIS_M PF07500.14 GAN11585.1 - 4.9e-26 91.4 0.4 4.9e-26 91.4 0.4 1.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GAN11585.1 - 3.5e-20 71.6 5.7 5.6e-20 70.9 5.7 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GAN11585.1 - 8.2e-11 41.8 4.1 8.2e-11 41.8 4.1 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LEDGF PF11467.8 GAN11585.1 - 3.2e-05 23.5 0.8 5.9e-05 22.7 0.8 1.5 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Terminase_2 PF03592.16 GAN11585.1 - 0.014 15.8 1.8 0.1 13.0 1.8 2.1 1 1 0 1 1 1 0 Terminase small subunit DUF908 PF06012.12 GAN11585.1 - 0.097 12.1 2.3 0.1 12.0 2.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SIR2 PF02146.17 GAN11586.1 - 2.5e-36 125.2 0.0 4.5e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAN11586.1 - 0.0024 17.6 0.0 0.73 9.6 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain AsmA_1 PF13109.6 GAN11586.1 - 0.024 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region DUF3886 PF13025.6 GAN11586.1 - 0.2 11.8 8.0 0.49 10.6 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Zn-ribbon_8 PF09723.10 GAN11586.1 - 0.22 11.7 2.5 0.32 11.1 1.5 1.8 2 0 0 2 2 2 0 Zinc ribbon domain FliT PF05400.13 GAN11587.1 - 1.6 9.6 4.2 20 6.1 0.0 3.4 3 0 0 3 3 3 0 Flagellar protein FliT Replic_Relax PF13814.6 GAN11589.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation V-SNARE_C PF12352.8 GAN11590.1 - 4.9e-13 49.1 1.9 4.9e-13 49.1 1.9 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAN11590.1 - 1.5e-06 28.0 2.0 2.1e-06 27.5 0.1 2.1 3 0 0 3 3 3 1 Sec20 Syntaxin-18_N PF10496.9 GAN11590.1 - 0.061 13.6 6.3 0.57 10.5 6.3 2.2 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus TPR_MLP1_2 PF07926.12 GAN11590.1 - 0.89 9.6 12.0 4.6 7.3 0.5 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RhoGAP PF00620.27 GAN11593.1 - 5.3e-32 110.7 0.2 8.6e-32 110.1 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 GAN11593.1 - 4.7e-27 94.8 0.5 9.7e-27 93.8 0.1 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAN11593.1 - 0.011 15.5 0.3 0.034 13.9 0.1 1.9 2 0 0 2 2 2 0 CRAL/TRIO domain DUF5537 PF17690.1 GAN11593.1 - 0.018 14.7 0.0 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5537) DUF1819 PF08849.11 GAN11593.1 - 0.064 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Acetyltransf_11 PF13720.6 GAN11593.1 - 0.092 13.2 0.1 1.8 9.1 0.0 2.8 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ApoB100_C PF12491.8 GAN11593.1 - 5.8 7.0 5.7 2.5 8.1 0.0 3.1 4 0 0 4 4 4 0 Apolipoprotein B100 C terminal RhoGAP PF00620.27 GAN11594.1 - 1.8e-42 144.7 0.5 4.4e-42 143.5 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 GAN11594.1 - 9.5e-16 58.2 3.1 9.9e-16 58.2 0.1 2.6 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 GAN11594.1 - 4.6e-05 23.8 0.1 4.6e-05 23.8 0.1 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PX PF00787.24 GAN11594.1 - 5.4e-05 23.1 0.0 0.00017 21.5 0.0 1.9 1 0 0 1 1 1 1 PX domain DivIC PF04977.15 GAN11594.1 - 0.00029 20.5 0.3 0.0021 17.8 0.4 2.3 2 0 0 2 2 2 1 Septum formation initiator PH_8 PF15409.6 GAN11594.1 - 0.00083 19.6 5.3 0.0011 19.2 0.1 3.5 4 0 0 4 4 4 1 Pleckstrin homology domain PH_9 PF15410.6 GAN11594.1 - 0.0066 16.8 0.3 1.2 9.5 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain NRBF2 PF08961.10 GAN11594.1 - 0.015 14.9 0.8 0.015 14.9 0.8 2.0 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator PH_6 PF15406.6 GAN11594.1 - 0.055 13.8 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF5101 PF17031.5 GAN11594.1 - 1.2 9.2 4.4 1.3 9.1 0.7 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5101) bZIP_2 PF07716.15 GAN11594.1 - 3 8.0 5.3 8.3 6.6 5.3 1.8 1 0 0 1 1 1 0 Basic region leucine zipper MyTH4 PF00784.17 GAN11595.1 - 1.2e-25 90.1 0.0 2.3e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 GAN11595.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain CotH PF08757.11 GAN11596.1 - 1.1e-35 123.7 5.1 2.2e-35 122.7 5.1 1.6 2 0 0 2 2 2 1 CotH kinase protein Ribosomal_L19e PF01280.20 GAN11597.1 - 2.8e-07 30.7 0.8 2.8e-07 30.7 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L19e OmdA PF13376.6 GAN11597.1 - 0.27 11.3 8.7 0.31 11.1 0.5 2.1 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated E1_DerP2_DerF2 PF02221.15 GAN11598.1 - 1e-12 48.7 0.0 1.3e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAN11598.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.4 1 1 0 1 1 1 0 ML-like domain Yae1_N PF09811.9 GAN11599.1 - 3.5e-08 33.0 2.3 4.8e-08 32.6 2.3 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal HisKA_2 PF07568.12 GAN11599.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase DMT_YdcZ PF04657.13 GAN11602.1 - 1.9e-27 96.2 11.2 2.4e-27 95.9 11.2 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ EamA PF00892.20 GAN11602.1 - 1.1 9.5 10.4 1.5 9.0 10.4 1.2 1 0 0 1 1 1 0 EamA-like transporter family Isochorismatase PF00857.20 GAN11604.1 - 8.8e-21 74.9 0.0 1.8e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family RasGEF PF00617.19 GAN11605.1 - 8.5e-59 198.7 0.8 2.2e-58 197.4 0.8 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAN11605.1 - 1.7e-29 102.1 1.9 1.3e-28 99.3 0.8 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif WW PF00397.26 GAN11605.1 - 0.0011 19.0 0.1 0.0035 17.4 0.1 2.0 1 0 0 1 1 1 1 WW domain GIT1_C PF12205.8 GAN11605.1 - 0.75 9.9 3.2 2.3 8.4 0.2 3.2 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term I_LWEQ PF01608.17 GAN11605.1 - 2.4 8.4 7.3 79 3.5 0.2 4.7 4 1 1 5 5 5 0 I/LWEQ domain PH PF00169.29 GAN11606.1 - 2e-19 70.0 0.7 6.6e-19 68.4 0.7 1.9 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 GAN11606.1 - 2.2e-15 56.2 0.4 1.6e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 GAN11606.1 - 1.1e-13 50.6 0.4 1.1e-13 50.6 0.4 2.0 2 0 0 2 2 2 1 SH3 domain SAM_2 PF07647.17 GAN11606.1 - 4.2e-13 49.2 0.1 5.1e-12 45.7 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 GAN11606.1 - 2.6e-10 39.8 0.1 5.5e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 GAN11606.1 - 1e-07 32.2 0.1 2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 GAN11606.1 - 3.8e-06 27.3 5.3 0.00054 20.3 5.3 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_PNT PF02198.16 GAN11606.1 - 0.002 18.1 1.2 0.34 10.9 0.0 2.8 2 1 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 GAN11606.1 - 0.0082 16.4 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 Ste50p, sterile alpha motif PH_8 PF15409.6 GAN11606.1 - 0.024 14.9 0.1 0.086 13.1 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 GAN11606.1 - 0.025 14.7 0.2 0.058 13.5 0.2 1.5 1 0 0 1 1 1 0 PH domain NOA36 PF06524.12 GAN11606.1 - 0.067 12.5 5.2 0.14 11.5 5.2 1.5 1 0 0 1 1 1 0 NOA36 protein Roughex PF06020.11 GAN11606.1 - 9.9 5.1 12.8 0.56 9.2 7.3 1.6 2 0 0 2 2 2 0 Drosophila roughex protein DUF3446 PF11928.8 GAN11607.1 - 8.4 6.8 18.2 6 7.2 10.4 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain HMG_box PF00505.19 GAN11608.1 - 1.1e-15 57.8 1.3 1.1e-15 57.8 1.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 GAN11608.1 - 4.3e-12 46.3 0.1 4.3e-12 46.3 0.1 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 GAN11608.1 - 2.7e-11 43.9 1.6 2.7e-11 43.9 1.6 2.4 1 1 1 2 2 2 1 HMG-box domain SAM_2 PF07647.17 GAN11608.1 - 4.2e-09 36.4 0.1 1e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 GAN11608.1 - 0.017 15.1 0.0 0.056 13.4 0.0 1.9 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) WYL_3 PF18488.1 GAN11608.1 - 0.017 15.5 1.1 0.045 14.1 1.1 1.7 1 0 0 1 1 1 0 WYL domain DDE_Tnp_1_7 PF13843.6 GAN11609.1 - 7.1e-10 38.7 0.6 4.8e-08 32.7 0.2 2.0 1 1 1 2 2 2 2 Transposase IS4 F-box-like PF12937.7 GAN11610.1 - 0.00023 21.0 0.2 0.00056 19.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GAN11610.1 - 0.012 15.5 0.5 0.027 14.4 0.5 1.7 1 0 0 1 1 1 0 F-box Thg1 PF04446.12 GAN11610.1 - 0.082 12.9 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 tRNAHis guanylyltransferase F-box PF00646.33 GAN11610.1 - 1.1 9.3 5.5 0.17 11.8 0.6 2.3 2 1 0 2 2 2 0 F-box domain zf-C2H2 PF00096.26 GAN11611.1 - 7.8e-17 60.7 46.2 0.00013 22.3 4.1 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAN11611.1 - 1.3e-09 38.0 34.8 0.00016 21.9 4.7 6.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAN11611.1 - 0.00028 21.5 56.3 0.012 16.4 3.3 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAN11611.1 - 0.017 15.1 0.6 0.017 15.1 0.6 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 GAN11611.1 - 0.11 13.2 0.3 0.11 13.2 0.3 6.6 7 0 0 7 7 7 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 GAN11611.1 - 1.3 9.1 8.5 3.7 7.6 0.1 4.0 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_9 PF16293.5 GAN11611.1 - 2.7 7.9 9.5 27 4.7 0.3 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_aberr PF17017.5 GAN11611.1 - 4.3 7.4 14.1 12 6.1 0.1 4.1 3 1 0 3 3 3 0 Aberrant zinc-finger Mis14 PF08641.12 GAN11612.1 - 0.00078 19.8 5.5 0.0011 19.2 4.5 1.8 1 1 0 1 1 1 1 Kinetochore protein Mis14 like Tht1 PF04163.12 GAN11612.1 - 0.012 14.4 1.2 0.02 13.7 0.8 1.4 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein TCTP PF00838.17 GAN11612.1 - 0.073 13.4 2.9 0.2 12.0 0.0 2.4 1 1 1 2 2 2 0 Translationally controlled tumour protein Syntaxin_2 PF14523.6 GAN11612.1 - 1.2 9.6 8.9 12 6.3 0.3 3.7 1 1 1 3 3 3 0 Syntaxin-like protein GCD14 PF08704.10 GAN11613.1 - 6.6e-90 301.1 0.0 7.8e-90 300.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 GAN11613.1 - 2.6e-05 24.1 0.0 5.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 GAN11613.1 - 0.00013 21.7 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 GAN11613.1 - 0.00075 19.3 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 GAN11613.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase vATP-synt_AC39 PF01992.16 GAN11614.1 - 3.4e-46 158.3 0.1 3.8e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit AAA_33 PF13671.6 GAN11615.1 - 1.3e-09 38.4 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAN11615.1 - 0.04 13.3 0.6 0.042 13.3 0.2 1.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CAF20 PF17052.5 GAN11615.1 - 0.18 11.9 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 Cap associated factor bZIP_1 PF00170.21 GAN11616.1 - 7.7e-11 41.9 11.1 9.4e-11 41.7 9.6 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAN11616.1 - 5.5e-07 29.6 7.6 5.5e-07 29.6 7.6 3.0 2 1 1 3 3 3 2 Basic region leucine zipper PRCC PF10253.9 GAN11616.1 - 0.0051 17.6 7.2 0.015 16.1 2.8 2.2 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting bZIP_Maf PF03131.17 GAN11616.1 - 0.0088 16.5 8.3 0.0088 16.5 8.3 1.9 2 0 0 2 2 1 1 bZIP Maf transcription factor TolA_bind_tri PF16331.5 GAN11616.1 - 0.025 14.6 4.7 0.025 14.6 4.7 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Macoilin PF09726.9 GAN11616.1 - 0.028 13.0 5.4 0.031 12.9 5.4 1.1 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 GAN11616.1 - 0.03 14.8 3.4 0.03 14.8 3.4 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Nsp1_C PF05064.13 GAN11616.1 - 0.068 13.0 1.9 0.17 11.7 1.9 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region Chibby PF14645.6 GAN11616.1 - 0.087 13.2 4.9 0.1 13.0 1.9 2.3 2 1 0 2 2 2 0 Chibby family YabA PF06156.13 GAN11616.1 - 0.15 12.7 3.7 0.081 13.6 1.3 1.8 2 0 0 2 2 1 0 Initiation control protein YabA RNase_HII PF01351.18 GAN11616.1 - 0.25 11.2 2.1 0.3 10.9 1.0 1.6 2 0 0 2 2 2 0 Ribonuclease HII ZapB PF06005.12 GAN11616.1 - 0.33 11.4 7.7 0.092 13.2 3.8 2.1 2 0 0 2 2 1 0 Cell division protein ZapB Peptidase_M27 PF01742.17 GAN11616.1 - 0.38 9.8 2.1 0.48 9.5 0.3 1.8 2 0 0 2 2 2 0 Clostridial neurotoxin zinc protease Jnk-SapK_ap_N PF09744.9 GAN11616.1 - 0.65 10.2 8.3 0.11 12.8 4.2 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Nif11 PF07862.11 GAN11616.1 - 0.66 10.3 3.6 1.9 8.9 0.1 2.6 2 1 0 2 2 2 0 Nif11 domain TMF_TATA_bd PF12325.8 GAN11616.1 - 0.82 9.9 8.4 0.16 12.2 4.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 GAN11616.1 - 2.5 8.8 8.5 23 5.7 0.3 2.6 2 0 0 2 2 2 0 SlyX PRKCSH-like PF12999.7 GAN11617.1 - 1.9e-49 167.8 7.9 1.9e-49 167.8 7.9 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 GAN11617.1 - 5.3e-32 110.6 0.8 5.3e-32 110.6 0.8 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 GAN11617.1 - 6.6e-06 27.0 0.7 6.6e-06 27.0 0.7 2.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein TPR_MLP1_2 PF07926.12 GAN11617.1 - 0.0067 16.5 11.8 0.069 13.2 6.8 2.5 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein RRN3 PF05327.11 GAN11617.1 - 0.54 8.7 6.6 0.72 8.3 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF745 PF05335.13 GAN11617.1 - 0.57 9.9 8.3 2.7 7.7 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF4407 PF14362.6 GAN11617.1 - 0.82 9.0 9.5 0.65 9.3 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 GAN11617.1 - 0.92 10.3 9.8 0.35 11.6 2.5 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4472) GAS PF13851.6 GAN11617.1 - 3.1 7.1 19.0 0.44 9.9 5.8 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 GAN11617.1 - 3.5 8.3 6.8 6.2 7.5 2.3 3.2 3 0 0 3 3 3 0 SlyX Rx_N PF18052.1 GAN11617.1 - 6.5 7.1 11.9 17 5.8 0.1 3.9 2 2 1 3 3 3 0 Rx N-terminal domain HIP1_clath_bdg PF16515.5 GAN11617.1 - 7.5 7.2 16.3 13 6.4 0.1 3.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 EF-hand_1 PF00036.32 GAN11618.1 - 0.0024 17.3 0.2 0.0055 16.2 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAN11618.1 - 0.014 15.8 0.1 0.041 14.3 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 GAN11618.1 - 0.032 14.1 0.1 0.092 12.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair DUF2951 PF11166.8 GAN11618.1 - 0.065 13.5 0.7 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Glyco_transf_9 PF01075.17 GAN11618.1 - 0.1 11.9 0.2 0.18 11.1 0.1 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) CN_hydrolase PF00795.22 GAN11619.1 - 4.3e-61 206.5 0.0 5e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LRR_8 PF13855.6 GAN11620.1 - 1e-17 63.6 17.9 1.2e-08 34.5 3.5 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAN11620.1 - 4.6e-12 46.0 26.2 3.4e-08 33.7 3.8 4.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAN11620.1 - 2e-06 27.5 13.1 3.3 8.6 0.1 6.4 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_9 PF14580.6 GAN11620.1 - 0.0054 16.3 9.3 0.0062 16.1 4.1 2.6 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 GAN11620.1 - 0.32 11.1 16.7 7.4 6.9 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich repeat zinc_ribbon_9 PF14369.6 GAN11620.1 - 1.4 9.3 4.2 18 5.7 0.8 2.8 2 0 0 2 2 2 0 zinc-ribbon 5_nucleotid_C PF02872.18 GAN11622.1 - 1.3e-35 122.9 0.0 4.5e-35 121.2 0.0 1.9 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 GAN11622.1 - 2.2e-07 31.6 0.2 3.6e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 GAN11623.1 - 1.7e-26 93.4 0.1 2.5e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAN11623.1 - 2e-05 24.6 0.2 0.19 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAN11623.1 - 0.00041 20.3 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 GAN11623.1 - 0.0017 17.8 0.0 0.0094 15.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 GAN11623.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 GAN11623.1 - 0.01 15.6 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain hEGF PF12661.7 GAN11623.1 - 0.015 15.9 7.0 0.015 15.9 7.0 3.9 4 0 0 4 4 4 0 Human growth factor-like EGF AAA_18 PF13238.6 GAN11623.1 - 0.031 14.8 0.0 0.082 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAN11623.1 - 0.032 14.6 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 GAN11623.1 - 0.039 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAN11623.1 - 0.067 13.4 0.1 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAN11623.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 GAN11623.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 GAN11623.1 - 0.27 10.8 0.4 0.75 9.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Exo_endo_phos_2 PF14529.6 GAN11625.1 - 1.7e-08 34.3 0.0 3.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN11625.1 - 6.1e-06 25.9 0.2 1.2e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GATA PF00320.27 GAN11626.1 - 1.1e-15 56.9 3.0 1.1e-15 56.9 3.0 1.9 2 0 0 2 2 2 1 GATA zinc finger DELLA PF12041.8 GAN11626.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Zn-ribbon_8 PF09723.10 GAN11626.1 - 0.14 12.3 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DAO PF01266.24 GAN11627.1 - 6.4e-15 55.6 0.0 7.9e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAN11627.1 - 0.00042 19.5 0.5 0.00067 18.9 0.3 1.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAN11627.1 - 0.00068 19.1 0.5 0.00068 19.1 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAN11627.1 - 0.0042 17.0 0.5 0.028 14.3 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 GAN11627.1 - 0.0057 15.9 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAN11627.1 - 0.011 15.9 0.5 0.026 14.7 0.4 1.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAN11627.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAN11627.1 - 0.17 10.5 0.5 0.32 9.6 0.5 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 GAN11627.1 - 0.23 10.5 1.5 0.24 10.5 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Ribosomal_L27A PF00828.19 GAN11630.1 - 1.7e-20 74.0 1.1 2.4e-20 73.5 1.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MFS_1 PF07690.16 GAN11631.1 - 3.6e-17 62.3 34.9 4.3e-13 48.9 18.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily RVT_1 PF00078.27 GAN11632.1 - 5.3e-16 58.8 0.2 1.2e-15 57.7 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GAN11632.1 - 1.4e-05 25.0 0.1 3.4e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 GAN11632.1 - 0.011 16.0 0.1 0.039 14.2 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein FlxA PF14282.6 GAN11632.1 - 0.029 14.4 0.0 0.088 12.8 0.0 1.8 1 0 0 1 1 1 0 FlxA-like protein Retrotran_gag_2 PF14223.6 GAN11632.1 - 0.045 13.4 0.5 0.15 11.7 0.2 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Peptidase_M13_N PF05649.13 GAN11633.1 - 9.8e-69 232.9 0.1 1.3e-68 232.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAN11633.1 - 2.9e-29 102.2 0.0 5.1e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Hexokinase_2 PF03727.16 GAN11634.1 - 4.5e-88 294.7 0.0 5.1e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Hexokinase PQ-loop PF04193.14 GAN11635.1 - 8.8e-18 63.8 0.7 8.8e-18 63.8 0.7 2.3 2 0 0 2 2 2 1 PQ loop repeat Lipase_GDSL PF00657.22 GAN11635.1 - 5.6e-16 59.1 0.1 7.8e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN11635.1 - 3.9e-08 33.9 0.0 6.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cation_ATPase_C PF00689.21 GAN11635.1 - 0.16 11.6 4.1 0.34 10.6 4.1 1.4 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus MtN3_slv PF03083.16 GAN11635.1 - 0.42 10.7 3.5 0.16 12.0 0.3 2.0 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Rhodanese PF00581.20 GAN11637.1 - 1.5e-11 44.7 0.0 2.4e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.26 GAN11639.1 - 1.5e-18 66.1 39.6 7.4e-05 23.0 5.0 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN11639.1 - 1.1e-10 41.3 34.5 0.0045 17.7 0.7 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAN11639.1 - 2.2e-08 34.1 29.9 8.8e-06 25.9 2.9 5.1 5 0 0 5 5 5 2 Zinc-finger double domain FOXP-CC PF16159.5 GAN11639.1 - 0.0051 17.4 1.3 0.062 13.9 0.1 3.9 4 0 0 4 4 4 2 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 GAN11639.1 - 1.5 8.7 12.9 5.4 6.9 0.2 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) RPAP2_Rtr1 PF04181.13 GAN11639.1 - 2.6 8.4 7.1 6.1 7.2 0.3 3.1 2 1 1 3 3 3 0 Rtr1/RPAP2 family zf-C2H2_aberr PF17017.5 GAN11639.1 - 3.5 7.7 17.8 2.8 8.1 2.0 4.2 2 2 2 4 4 4 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 GAN11640.1 - 0.0011 19.7 86.9 0.17 12.8 0.4 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 GAN11640.1 - 0.018 15.4 0.2 0.018 15.4 0.2 8.8 9 0 0 9 9 9 0 Zinc-finger of C2H2 type Tox-ODYAM1 PF15642.6 GAN11640.1 - 0.11 11.5 1.9 0.17 10.8 1.9 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus zf-C2H2_jaz PF12171.8 GAN11640.1 - 2.1 8.7 82.6 0.31 11.4 1.7 9.6 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding KIX_2 PF16987.5 GAN11641.1 - 0.13 12.3 1.7 0.22 11.5 0.2 2.1 2 0 0 2 2 2 0 KIX domain Cation_efflux PF01545.21 GAN11642.1 - 1.3e-48 165.4 3.4 1.8e-48 164.9 3.4 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAN11642.1 - 4.2e-13 49.2 0.9 7.2e-13 48.5 0.9 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PMBR PF09373.10 GAN11643.1 - 3.5e-05 23.8 0.1 0.00013 21.9 0.0 2.1 2 0 0 2 2 2 1 Pseudomurein-binding repeat ResIII PF04851.15 GAN11643.1 - 0.00064 19.8 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAN11643.1 - 0.0039 17.0 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN11643.1 - 0.0056 17.0 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_S3Ae PF01015.18 GAN11644.1 - 9.5e-63 211.4 3.6 1.2e-62 211.1 3.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family NDC10_II PF16787.5 GAN11647.1 - 9.8e-07 28.1 0.0 1.1e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Ribosomal_L18 PF17135.4 GAN11649.1 - 5.4e-88 293.3 5.3 6.3e-88 293.1 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAN11649.1 - 0.0014 19.3 0.3 0.0036 18.0 0.3 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4481 PF14800.6 GAN11650.1 - 0.0046 16.5 0.5 0.0064 16.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) Stimulus_sens_1 PF13756.6 GAN11650.1 - 0.34 11.5 2.7 0.62 10.7 0.2 2.3 2 1 0 3 3 3 0 Stimulus-sensing domain Vfa1 PF08432.10 GAN11650.1 - 4.2 7.7 11.7 0.11 12.9 4.9 1.8 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AA_permease PF00324.21 GAN11652.1 - 8.6e-134 446.7 45.8 1.1e-133 446.4 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAN11652.1 - 3.9e-46 157.7 50.6 5.3e-46 157.3 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease G5 PF07501.12 GAN11653.1 - 0.027 14.9 1.8 1.1 9.7 1.1 2.3 2 0 0 2 2 2 0 G5 domain KcnmB2_inactiv PF09303.10 GAN11653.1 - 0.13 12.1 0.2 0.33 10.8 0.2 1.7 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Abhydrolase_1 PF00561.20 GAN11654.1 - 1.2e-32 113.5 0.0 5.1e-32 111.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAN11654.1 - 8.6e-21 75.6 0.0 1.1e-20 75.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAN11654.1 - 9e-13 48.0 0.0 1.9e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 GAN11654.1 - 8.1e-05 23.0 0.0 0.00022 21.6 0.0 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Peptidase_S9 PF00326.21 GAN11654.1 - 0.0016 17.9 0.1 0.14 11.6 0.0 2.9 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 GAN11654.1 - 0.044 13.9 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 GAN11654.1 - 0.046 12.4 0.0 0.09 11.5 0.0 1.5 1 0 0 1 1 1 0 Ndr family PGAP1 PF07819.13 GAN11654.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Proton_antipo_M PF00361.20 GAN11655.1 - 3.5e-61 207.0 17.5 3.5e-61 207.0 17.5 1.5 1 1 1 2 2 2 1 Proton-conducting membrane transporter UPF0300 PF08594.10 GAN11655.1 - 0.059 12.7 0.2 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0300) Gram_pos_anchor PF00746.21 GAN11655.1 - 6.3 6.8 7.3 0.46 10.5 0.3 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Aa_trans PF01490.18 GAN11656.1 - 1.2e-61 208.6 27.7 1.5e-61 208.4 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 7TMR-DISM_7TM PF07695.11 GAN11656.1 - 0.0085 16.0 9.6 0.0085 16.0 9.6 3.3 2 1 1 3 3 3 1 7TM diverse intracellular signalling DUF5579 PF17742.1 GAN11656.1 - 0.17 11.4 1.7 0.33 10.5 1.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5579) 4HBT PF03061.22 GAN11657.1 - 6.8e-15 55.2 0.2 1e-14 54.6 0.1 1.4 2 0 0 2 2 2 1 Thioesterase superfamily NuA4 PF09340.10 GAN11658.1 - 1.9e-23 82.1 0.1 1.9e-23 82.1 0.1 2.2 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Mucin PF01456.17 GAN11658.1 - 0.011 15.7 31.0 0.018 15.0 31.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Hamartin PF04388.12 GAN11658.1 - 1.3 7.6 19.0 1.5 7.4 19.0 1.0 1 0 0 1 1 1 0 Hamartin protein Sporozoite_P67 PF05642.11 GAN11658.1 - 2.5 6.1 19.6 0.0099 14.0 8.8 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Endomucin PF07010.12 GAN11658.1 - 2.8 7.9 23.9 3.5 7.5 23.9 1.1 1 0 0 1 1 1 0 Endomucin Med3 PF11593.8 GAN11658.1 - 3.6 6.7 23.0 5.8 6.0 23.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAS_C PF12026.8 GAN11658.1 - 4.8 7.2 9.4 0.29 11.2 3.7 1.7 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain AflR PF08493.10 GAN11658.1 - 6.4 6.2 16.9 11 5.4 16.9 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein CCDC106 PF15794.5 GAN11658.1 - 7.5 6.2 18.0 3.9 7.1 6.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 NAD_binding_4 PF07993.12 GAN11659.1 - 7.1e-21 74.5 0.0 9.6e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAN11659.1 - 0.0094 15.4 0.2 0.035 13.6 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAN11659.1 - 0.023 13.7 1.3 0.87 8.5 0.1 2.5 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1199 PF06712.11 GAN11659.1 - 2.4 8.2 8.6 1.5 8.9 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1199) ECH_1 PF00378.20 GAN11660.1 - 1.2e-74 250.8 0.3 1.6e-74 250.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAN11660.1 - 1.4e-32 113.5 0.3 2e-32 113.0 0.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAN11660.1 - 0.00072 19.5 0.2 0.06 13.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Gtr1_RagA PF04670.12 GAN11661.1 - 2.1e-103 344.7 0.3 2.6e-103 344.4 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAN11661.1 - 2.6e-09 36.8 0.1 5e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAN11661.1 - 3.2e-09 37.0 0.3 1.1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAN11661.1 - 3e-08 33.4 0.0 5.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAN11661.1 - 4.2e-07 30.1 0.0 7.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAN11661.1 - 0.00029 20.5 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAN11661.1 - 0.0013 18.6 0.3 1.9 8.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 GAN11661.1 - 0.0039 17.7 0.2 0.011 16.2 0.1 1.7 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.10 GAN11661.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 GAN11661.1 - 0.027 13.6 0.4 0.098 11.8 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 GAN11661.1 - 0.041 13.6 0.3 0.24 11.1 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 GAN11661.1 - 0.16 11.7 0.4 0.37 10.6 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 GAN11661.1 - 0.53 9.4 5.8 7.1 5.7 0.8 2.6 2 1 1 3 3 3 0 G-protein alpha subunit MFS_1 PF07690.16 GAN11662.1 - 8e-49 166.4 42.0 1.2e-48 165.9 42.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN11662.1 - 1.1e-14 54.2 30.1 2.3e-14 53.1 5.5 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2929 PF11151.8 GAN11662.1 - 0.77 10.1 8.2 3.5 8.0 0.7 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) FAR1 PF03101.15 GAN11663.1 - 2.8e-05 24.7 2.9 6.3e-05 23.6 2.9 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain GTP_EFTU_D3 PF03143.17 GAN11663.1 - 0.045 14.0 0.8 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain CdiA_C PF18451.1 GAN11663.1 - 1.7 8.9 5.5 5.3 7.3 0.5 3.2 1 1 2 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain bZIP_2 PF07716.15 GAN11665.1 - 3.9e-12 46.0 8.7 8.4e-12 45.0 8.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAN11665.1 - 0.00017 21.6 9.2 0.00035 20.6 9.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 GAN11665.1 - 0.006 16.3 1.5 0.014 15.2 1.5 1.6 1 0 0 1 1 1 1 Septum formation initiator Fib_alpha PF08702.10 GAN11665.1 - 0.007 16.6 3.4 0.012 15.8 3.4 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 GAN11665.1 - 0.0071 16.4 2.9 0.013 15.5 2.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 GAN11665.1 - 0.0073 15.0 2.5 0.01 14.5 2.5 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A PspB PF06667.12 GAN11665.1 - 0.049 13.7 0.9 0.11 12.6 0.9 1.5 1 0 0 1 1 1 0 Phage shock protein B Activator_LAG-3 PF11498.8 GAN11665.1 - 0.052 12.5 0.2 0.052 12.5 0.2 1.8 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF1465 PF07323.12 GAN11665.1 - 0.054 13.3 3.9 0.1 12.4 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DUF2203 PF09969.9 GAN11665.1 - 0.086 13.6 2.1 0.15 12.7 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF5446 PF17522.2 GAN11665.1 - 1 9.6 4.8 1.7 8.9 1.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5446) NAM-associated PF14303.6 GAN11665.1 - 2.2 8.9 12.7 4.8 7.9 5.0 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain XhlA PF10779.9 GAN11665.1 - 2.5 8.4 4.8 0.67 10.2 0.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF3552 PF12072.8 GAN11666.1 - 0.015 14.7 3.6 0.015 14.7 3.6 4.3 1 1 2 4 4 4 0 Domain of unknown function (DUF3552) HIP1_clath_bdg PF16515.5 GAN11666.1 - 0.019 15.5 23.4 0.019 15.5 23.4 5.3 2 2 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 GAN11666.1 - 0.034 14.2 62.8 0.028 14.5 17.4 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sugar_tr PF00083.24 GAN11667.1 - 5.8e-121 404.5 20.4 6.8e-121 404.3 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN11667.1 - 1.7e-38 132.5 34.4 3.7e-31 108.3 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAN11667.1 - 0.00037 19.1 0.6 0.00037 19.1 0.6 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) RT_RNaseH PF17917.1 GAN11668.1 - 9.6e-30 103.0 0.1 9.6e-30 103.0 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN11668.1 - 4.4e-28 97.2 0.1 1e-27 96.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 GAN11668.1 - 1.8e-17 63.7 0.0 6.8e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 GAN11668.1 - 1.8e-16 59.9 0.7 3.8e-16 58.9 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 GAN11668.1 - 8.8e-10 38.5 0.1 2e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 GAN11668.1 - 9e-06 25.4 0.1 2.6e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GAN11668.1 - 0.003 17.7 2.1 0.0046 17.1 0.2 2.3 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 GAN11669.1 - 2.4e-08 33.8 0.0 4.4e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhyH PF05721.13 GAN11674.1 - 1.4e-53 182.3 0.0 1.6e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAN11674.1 - 0.044 14.2 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Exo_endo_phos_2 PF14529.6 GAN11675.1 - 7.2e-10 38.8 0.3 7.2e-10 38.8 0.3 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN11675.1 - 0.0049 16.4 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HNH PF01844.23 GAN11675.1 - 0.0088 16.2 0.2 0.0088 16.2 0.2 2.2 2 0 0 2 2 2 1 HNH endonuclease zf-CCHC PF00098.23 GAN11675.1 - 0.014 15.4 0.4 0.014 15.4 0.4 2.9 2 0 0 2 2 2 0 Zinc knuckle DUF4195 PF13836.6 GAN11675.1 - 0.28 11.3 3.5 0.58 10.3 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) DUF1749 PF08538.10 GAN11677.1 - 3.2e-62 210.3 0.0 3.8e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 GAN11677.1 - 3.3e-05 23.3 0.0 0.0092 15.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF915 PF06028.11 GAN11677.1 - 0.026 13.8 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 GAN11677.1 - 0.028 14.0 0.3 0.43 10.1 0.0 2.3 2 1 1 3 3 3 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 GAN11677.1 - 0.071 13.7 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 GAN11677.1 - 0.097 12.2 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Peripla_BP_6 PF13458.6 GAN11677.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein GATA PF00320.27 GAN11678.1 - 2.5e-29 100.6 15.9 2.3e-15 55.9 4.1 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 GAN11678.1 - 1.1e-11 44.3 1.6 1.1e-11 44.3 1.6 2.7 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1752) DZR PF12773.7 GAN11678.1 - 0.00016 21.6 2.3 0.00076 19.5 1.5 2.5 1 1 2 3 3 3 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 GAN11678.1 - 0.0013 18.2 5.7 0.035 13.6 0.3 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 GAN11678.1 - 0.0016 18.5 0.9 2.1 8.6 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 GAN11678.1 - 0.083 13.1 4.7 3.1 8.0 0.3 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF5538 PF17692.1 GAN11678.1 - 0.14 12.3 2.7 0.35 10.9 2.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5538) eIF-5_eIF-2B PF01873.17 GAN11678.1 - 0.76 9.7 5.1 6.8 6.6 0.7 2.8 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-RRPl_C4 PF17026.5 GAN11678.1 - 1.3 9.1 8.9 0.95 9.6 0.4 3.2 2 1 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 GAN11678.1 - 1.4 9.7 5.0 14 6.6 2.9 3.1 1 1 2 3 3 3 0 zinc-ribbon family RNA_pol_A_bac PF01000.26 GAN11679.1 - 4.3e-30 104.4 0.0 8.5e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAN11679.1 - 6.6e-22 76.7 0.0 9.2e-22 76.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Adeno_52K PF03052.15 GAN11679.1 - 0.052 13.0 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa cNMP_binding PF00027.29 GAN11682.1 - 2.8e-30 104.2 0.1 2.7e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 GAN11682.1 - 4.5e-10 39.0 0.7 7.9e-10 38.3 0.7 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF2145 PF09916.9 GAN11682.1 - 0.16 11.6 0.1 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2145) zf-C2H2_4 PF13894.6 GAN11683.1 - 2.9e-05 24.5 10.1 0.062 14.2 1.7 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAN11683.1 - 0.004 17.5 12.4 0.4 11.2 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 GAN11683.1 - 0.19 12.1 7.9 6.1 7.2 8.0 2.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 GAN11683.1 - 0.4 11.0 4.7 2.9 8.3 0.7 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 GAN11683.1 - 0.5 10.9 9.4 0.99 10.0 0.4 3.8 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAN11683.1 - 0.77 10.1 5.6 2.8 8.3 2.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAN11683.1 - 1.1 9.4 8.2 9.1 6.4 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 GAN11683.1 - 2.3 8.1 6.1 4.1 7.3 0.9 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF629 PF04780.12 GAN11683.1 - 2.8 6.4 8.6 0.43 9.0 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) G-patch PF01585.23 GAN11684.1 - 1.8e-15 56.5 2.3 3.8e-15 55.5 2.3 1.6 1 0 0 1 1 1 1 G-patch domain zf-met PF12874.7 GAN11684.1 - 3e-06 27.4 1.3 6.5e-06 26.4 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 GAN11684.1 - 3.3e-06 27.1 0.2 3.3e-06 27.1 0.2 2.2 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 GAN11684.1 - 4.7e-06 26.7 7.4 1.1e-05 25.5 7.4 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 GAN11684.1 - 0.0035 17.4 6.7 0.0077 16.3 6.7 1.6 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.7 GAN11684.1 - 0.0066 16.8 5.2 0.012 16.0 5.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 GAN11684.1 - 0.031 14.7 1.7 0.066 13.7 1.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAN11684.1 - 0.054 14.4 0.2 0.14 13.1 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAN11684.1 - 0.17 12.1 6.6 0.46 10.6 6.7 1.6 1 1 0 1 1 1 0 Aberrant zinc-finger O-antigen_lig PF13425.6 GAN11684.1 - 6.3 5.5 12.8 8.2 5.1 12.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PP-binding PF00550.25 GAN11685.1 - 7e-13 48.7 0.3 9e-13 48.4 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAN11685.1 - 2.7e-05 24.3 0.4 3.3e-05 24.0 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier hnRNP_Q_AcD PF18360.1 GAN11685.1 - 0.0098 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF3050 PF11251.8 GAN11686.1 - 0.0021 17.7 0.1 0.0053 16.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) GvpL_GvpF PF06386.11 GAN11686.1 - 0.044 13.7 0.1 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Pex14_N PF04695.13 GAN11686.1 - 0.06 14.0 0.4 0.06 14.0 0.4 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5051 PF16473.5 GAN11686.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like IZUMO PF15005.6 GAN11686.1 - 3.4 8.2 6.6 0.81 10.2 2.2 2.0 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Sel1 PF08238.12 GAN11688.1 - 3.7e-20 71.9 6.9 3.9e-08 33.7 1.6 4.1 4 0 0 4 4 4 3 Sel1 repeat TPR_1 PF00515.28 GAN11688.1 - 0.075 12.9 1.0 5.3 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAN11688.1 - 0.83 9.7 7.3 4.3 7.4 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc13p PF05839.11 GAN11689.1 - 0.00011 22.4 2.3 0.0002 21.5 2.3 1.4 1 1 0 1 1 1 1 Apc13p protein Ribosomal_L6e PF01159.19 GAN11690.1 - 1.5e-37 128.5 0.2 1.5e-37 128.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 GAN11690.1 - 2.7e-11 43.6 0.7 9e-11 41.9 0.7 2.0 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain MitMem_reg PF13012.6 GAN11691.1 - 1.8e-40 137.9 0.3 2.7e-40 137.3 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAN11691.1 - 6.6e-09 35.8 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AcMNPV_Ac109 PF05054.12 GAN11691.1 - 0.011 14.9 0.1 0.03 13.4 0.1 1.5 1 1 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF5536 PF17688.1 GAN11691.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5536) RT_RNaseH_2 PF17919.1 GAN11692.1 - 2.3e-35 120.6 0.0 4.8e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAN11692.1 - 5.2e-34 116.7 0.0 1.4e-33 115.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAN11692.1 - 6.3e-27 94.5 0.0 1.1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAN11692.1 - 9.3e-20 71.0 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GAN11692.1 - 6.2e-16 58.3 0.3 1.2e-15 57.3 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 GAN11692.1 - 0.0018 18.0 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Lyase_1 PF00206.20 GAN11693.1 - 9.1e-22 77.8 0.0 1.2e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 GAN11693.1 - 2.2e-16 60.2 0.0 9.3e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 GAN11693.1 - 0.0096 15.6 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1331) DDE_Tnp_1_7 PF13843.6 GAN11694.1 - 9.6e-18 64.6 0.0 2.5e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 Transposase IS4 Forkhead PF00250.18 GAN11696.1 - 9.5e-35 118.7 0.1 3.2e-34 117.0 0.1 1.9 1 0 0 1 1 1 1 Forkhead domain Homeodomain PF00046.29 GAN11697.1 - 6.1e-19 67.6 2.7 6.1e-19 67.6 2.7 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 GAN11697.1 - 0.0011 18.9 0.4 0.0033 17.3 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF1645 PF07816.11 GAN11697.1 - 0.023 15.3 2.6 0.023 15.3 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Homez PF11569.8 GAN11697.1 - 0.065 12.7 0.2 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Pex24p PF06398.11 GAN11698.1 - 7.6e-11 41.6 14.5 2.2e-10 40.1 14.5 1.7 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DEAD PF00270.29 GAN11699.1 - 2.5e-41 141.4 0.4 3.8e-41 140.8 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAN11699.1 - 7.2e-32 110.0 0.2 2.1e-30 105.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAN11699.1 - 3.9e-08 33.5 0.0 1.2e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNase_H2_suC PF08615.11 GAN11699.1 - 0.081 13.1 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DnaI_N PF07319.11 GAN11699.1 - 0.17 12.6 3.0 6.5 7.5 0.2 3.4 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus NOA36 PF06524.12 GAN11699.1 - 5.5 6.2 7.1 9.6 5.4 7.1 1.3 1 0 0 1 1 1 0 NOA36 protein Ecl1 PF12855.7 GAN11700.1 - 0.82 10.8 19.5 1.4 10.0 19.5 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins F-box-like PF12937.7 GAN11701.1 - 2.7e-06 27.2 0.1 5.5e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Na_Ca_ex PF01699.24 GAN11702.1 - 9.7e-39 132.7 42.2 1.7e-22 80.0 12.5 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein ATP-synt_8 PF00895.20 GAN11702.1 - 0.47 11.0 3.2 0.55 10.7 0.1 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 DHHC PF01529.20 GAN11703.1 - 2.4e-33 115.1 15.9 3.2e-33 114.7 15.9 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase UCR_TM PF02921.14 GAN11703.1 - 0.86 10.1 0.0 0.86 10.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region DDE_3 PF13358.6 GAN11704.1 - 1.8e-06 27.7 0.1 2.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 GAN11705.1 - 1.4e-71 241.0 0.1 4.2e-71 239.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAN11705.1 - 5.4e-36 124.2 0.0 8.8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAN11705.1 - 0.00045 19.6 0.0 0.001 18.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAN11705.1 - 0.091 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glu_synthase PF01645.17 GAN11705.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase Peptidase_S64 PF08192.11 GAN11705.1 - 1.7 7.0 12.9 2.1 6.7 12.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Homeodomain PF00046.29 GAN11706.1 - 4.9e-18 64.7 1.3 4.9e-18 64.7 1.3 2.1 2 0 0 2 2 2 1 Homeodomain YdaS_antitoxin PF15943.5 GAN11706.1 - 0.025 14.4 0.1 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 GAN11706.1 - 0.083 12.8 0.5 0.22 11.4 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain WD40 PF00400.32 GAN11707.1 - 2.2e-15 56.8 6.0 1.7e-05 25.5 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 GAN11707.1 - 1.1e-10 41.6 0.0 1.4e-08 34.9 0.0 3.2 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 GAN11707.1 - 5.1e-07 29.9 1.0 0.01 16.1 0.4 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN11707.1 - 6.4e-06 26.2 0.2 0.0019 18.1 0.2 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CH PF00307.31 GAN11708.1 - 6.1e-81 267.7 2.9 3.9e-21 75.3 0.0 4.6 5 0 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAN11708.1 - 1.7e-12 47.0 0.0 0.00053 19.8 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.32 GAN11708.1 - 0.00012 21.3 0.4 1.2 8.8 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAN11708.1 - 0.00037 20.9 0.5 0.0018 18.7 0.5 2.2 1 0 0 1 1 1 1 EF-hand domain pair CH_2 PF06294.11 GAN11708.1 - 0.0024 17.9 0.3 2.7 8.2 0.0 3.6 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_6 PF13405.6 GAN11708.1 - 0.0042 16.9 0.9 1.9 8.6 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain DDE_3 PF13358.6 GAN11709.1 - 1.2e-16 60.8 0.0 2.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Nuc_sug_transp PF04142.15 GAN11710.1 - 6.1e-122 406.7 16.4 7.4e-122 406.4 16.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAN11710.1 - 6.6e-09 36.0 26.1 1.4e-05 25.3 3.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family DPBB_1 PF03330.18 GAN11711.1 - 0.0043 17.3 0.8 0.1 12.9 0.2 2.8 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 GAN11711.1 - 0.015 15.2 0.2 0.032 14.1 0.2 1.6 1 1 0 1 1 1 0 Barwin family AAA_29 PF13555.6 GAN11711.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyclin PF08613.11 GAN11712.1 - 3.3e-07 30.8 9.5 3.3e-07 30.8 9.5 4.5 3 2 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 GAN11712.1 - 0.00046 19.9 0.0 0.00046 19.9 0.0 3.4 4 0 0 4 4 4 1 Cyclin, N-terminal domain Rieske PF00355.26 GAN11714.1 - 7.1e-12 45.1 0.0 1.5e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GAN11714.1 - 2.9e-11 43.7 2.0 7.6e-11 42.3 0.6 2.3 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Transp_cyt_pur PF02133.15 GAN11714.1 - 0.087 11.6 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin PsaN PF05479.11 GAN11714.1 - 2.5 8.3 5.3 0.62 10.2 0.7 2.0 1 1 1 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Ribosomal_L21e PF01157.18 GAN11715.1 - 2.7e-42 142.7 1.7 3e-42 142.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L21e p450 PF00067.22 GAN11716.1 - 4.8e-54 183.8 0.0 5.9e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 G-alpha PF00503.20 GAN11717.1 - 3.7e-106 355.2 6.5 5.1e-106 354.8 6.5 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAN11717.1 - 2.1e-14 53.4 1.4 7.7e-09 35.2 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAN11717.1 - 0.0001 22.5 0.4 0.5 10.6 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAN11717.1 - 0.002 17.5 2.5 0.74 9.1 0.2 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 GAN11717.1 - 0.0024 17.6 0.9 0.0034 17.1 0.9 1.3 1 0 0 1 1 1 1 AAA ATPase domain PhoPQ_related PF10142.9 GAN11717.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein MMR_HSR1 PF01926.23 GAN11717.1 - 0.036 14.2 0.2 3.1 7.9 0.2 2.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 GAN11717.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain C9orf72-like PF15019.6 GAN11718.1 - 2.3e-62 210.7 1.4 4.2e-62 209.9 1.4 1.3 1 0 0 1 1 1 1 C9orf72-like protein family DciA PF05258.12 GAN11718.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA Beta-lactamase PF00144.24 GAN11719.1 - 7.6e-38 130.6 2.3 1e-36 126.9 2.3 2.0 1 1 0 1 1 1 1 Beta-lactamase DUF4442 PF14539.6 GAN11720.1 - 1.1e-16 61.1 0.0 1.7e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) MTA_R1 PF17226.2 GAN11720.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 MTA R1 domain FixQ PF05545.11 GAN11720.1 - 0.3 11.1 1.1 0.51 10.3 0.4 1.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Exo_endo_phos_2 PF14529.6 GAN11721.1 - 1.1e-12 47.8 0.3 1.7e-12 47.2 0.3 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN11721.1 - 0.0023 17.5 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BNIP3 PF06553.12 GAN11722.1 - 0.00069 19.3 0.9 0.0017 18.1 0.9 1.6 1 0 0 1 1 1 1 BNIP3 TrbM PF07424.11 GAN11722.1 - 0.19 11.7 2.2 7.3 6.5 0.1 2.3 2 0 0 2 2 2 0 TrbM EDR1 PF14381.6 GAN11722.1 - 0.49 10.1 0.1 0.49 10.1 0.1 2.2 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 UPF0061 PF02696.14 GAN11722.1 - 2.4 6.8 10.9 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized ACR, YdiU/UPF0061 family Ly49 PF08391.10 GAN11722.1 - 5.5 7.4 8.4 22 5.4 1.7 2.7 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Ala_racemase_N PF01168.20 GAN11723.1 - 2.9e-23 82.7 0.0 3.8e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 GAN11723.1 - 2.6e-21 76.1 0.1 5.3e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain MHC_I_C PF06623.11 GAN11723.1 - 0.025 14.5 0.2 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 MHC_I C-terminus Homeodomain PF00046.29 GAN11724.1 - 8e-18 64.0 1.2 2.1e-17 62.7 1.2 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAN11724.1 - 0.0059 16.5 0.1 0.029 14.3 0.1 2.3 1 0 0 1 1 1 1 Homeobox KN domain Lar_restr_allev PF14354.6 GAN11725.1 - 0.0001 22.6 0.2 0.00023 21.5 0.2 1.6 1 0 0 1 1 1 1 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 GAN11725.1 - 0.028 14.2 0.6 0.43 10.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 GAN11725.1 - 0.042 13.8 2.6 0.073 13.1 0.6 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_7 PF02591.15 GAN11725.1 - 0.057 13.6 2.3 0.28 11.4 0.2 2.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-C4_Topoisom PF01396.19 GAN11725.1 - 0.093 12.5 0.3 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_10 PF10058.9 GAN11725.1 - 0.14 11.9 2.6 0.64 9.8 0.1 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 GAN11725.1 - 0.14 11.6 2.1 0.74 9.3 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.6 GAN11725.1 - 0.15 12.0 1.2 17 5.4 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 GAN11725.1 - 0.25 11.0 1.6 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Glyco_trans_2_3 PF13632.6 GAN11727.1 - 2.6e-14 53.6 0.6 2.6e-14 53.6 0.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MFS_1 PF07690.16 GAN11728.1 - 3.2e-32 111.8 70.9 6.9e-29 100.9 39.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAN11728.1 - 5.7e-05 22.2 32.9 0.0029 16.5 11.0 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter WD40 PF00400.32 GAN11729.1 - 4e-37 125.6 12.2 6.3e-08 33.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAN11729.1 - 1.4e-15 57.4 1.2 0.0007 19.8 0.2 5.4 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAN11729.1 - 5.2e-06 26.5 0.6 0.13 12.2 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 GAN11729.1 - 0.027 14.1 0.0 0.1 12.1 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 GAN11729.1 - 0.029 13.0 0.1 0.085 11.5 0.0 1.8 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAN11729.1 - 0.12 11.3 2.5 8 5.3 0.1 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ZZ PF00569.17 GAN11730.1 - 2.5e-11 43.2 5.9 4.1e-11 42.5 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 GAN11730.1 - 0.00015 21.1 0.2 0.00045 19.6 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAN11730.1 - 0.00075 19.2 0.3 0.0095 15.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain TackOD1 PF18551.1 GAN11730.1 - 0.0014 18.4 0.8 0.0022 17.7 0.8 1.4 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 EF-hand_8 PF13833.6 GAN11730.1 - 0.005 16.7 0.3 0.015 15.2 0.3 1.8 1 1 0 1 1 1 1 EF-hand domain pair C1_2 PF03107.16 GAN11730.1 - 0.0087 16.3 3.3 0.016 15.5 3.3 1.4 1 0 0 1 1 1 1 C1 domain EF-hand_7 PF13499.6 GAN11730.1 - 0.13 12.7 0.7 0.52 10.8 0.7 2.1 1 1 0 1 1 1 0 EF-hand domain pair Methylase_S PF01420.19 GAN11730.1 - 0.17 12.1 0.1 0.82 9.9 0.0 2.0 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain SR-25 PF10500.9 GAN11730.1 - 0.21 11.1 8.9 0.31 10.6 8.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Asp2 PF16929.5 GAN11731.1 - 0.045 12.7 0.1 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter DUF498 PF04430.14 GAN11733.1 - 3.8e-29 100.9 0.0 8.4e-29 99.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) Methyltransf_22 PF13383.6 GAN11733.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GST_C_3 PF14497.6 GAN11734.1 - 1e-15 57.7 0.1 2.3e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAN11734.1 - 1.9e-05 24.8 0.0 3.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAN11734.1 - 0.0017 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAN11734.1 - 0.002 18.1 0.1 0.0046 17.0 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF1462 PF07315.11 GAN11734.1 - 0.01 16.1 0.0 4.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) GST_N_4 PF17172.4 GAN11734.1 - 0.012 16.4 0.0 0.024 15.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Suppressor_APC PF11414.8 GAN11736.1 - 0.012 15.6 0.9 0.36 10.9 0.1 2.8 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein Spheroidin PF05541.12 GAN11741.1 - 0.00023 19.2 0.4 0.00025 19.1 0.4 1.0 1 0 0 1 1 1 1 Entomopoxvirus spheroidin protein Pro_isomerase PF00160.21 GAN11742.1 - 6e-48 163.1 0.1 7.3e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4134 PF13572.6 GAN11742.1 - 0.087 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) DUF4652 PF15525.6 GAN11743.1 - 1 9.1 10.0 1.3 8.8 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) FAM76 PF16046.5 GAN11743.1 - 2.2 7.5 21.2 2.8 7.2 21.2 1.0 1 0 0 1 1 1 0 FAM76 protein Otopetrin PF03189.13 GAN11743.1 - 5.1 5.8 10.8 7.3 5.3 10.8 1.3 1 0 0 1 1 1 0 Otopetrin Podoplanin PF05808.11 GAN11743.1 - 9.7 6.3 15.0 18 5.4 14.9 1.5 1 1 0 1 1 1 0 Podoplanin Herpes_Helicase PF02689.14 GAN11745.1 - 0.011 13.7 0.0 0.011 13.7 0.0 1.0 1 0 0 1 1 1 0 Helicase UvrD_C_2 PF13538.6 GAN11745.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 GAN11745.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase gag-asp_proteas PF13975.6 GAN11746.1 - 4.5e-07 30.4 0.0 0.0033 17.9 0.0 2.9 1 1 1 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAN11746.1 - 2.2e-06 28.2 0.0 0.00039 21.0 0.0 2.7 1 1 1 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 GAN11746.1 - 6.2e-06 26.0 0.5 6.3e-05 22.8 0.4 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 GAN11746.1 - 0.00075 19.5 4.3 0.0013 18.7 4.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 GAN11746.1 - 0.021 14.6 0.3 2.1 8.1 0.0 2.3 1 1 1 2 2 2 0 Aspartyl protease DUF2023 PF09633.10 GAN11747.1 - 0.038 14.1 0.3 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2023) Toxin_35 PF10530.9 GAN11748.1 - 0.0094 15.9 4.7 0.011 15.7 4.7 1.1 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Fungus-induced PF10917.8 GAN11748.1 - 0.092 13.1 0.4 0.27 11.6 0.2 1.9 2 1 0 2 2 2 0 Fungus-induced protein Toxin_12 PF07740.12 GAN11748.1 - 0.33 11.7 9.2 0.99 10.2 9.1 1.8 1 1 0 1 1 1 0 Ion channel inhibitory toxin ANF_receptor PF01094.28 GAN11749.1 - 3.9e-25 88.7 4.6 1.5e-24 86.8 4.6 1.8 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 GAN11749.1 - 0.0031 17.2 0.7 0.02 14.6 0.2 2.4 2 1 0 2 2 2 1 Periplasmic binding protein adh_short_C2 PF13561.6 GAN11750.1 - 7.4e-63 212.2 0.5 9.2e-63 211.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAN11750.1 - 4.8e-57 192.6 1.3 6e-57 192.3 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAN11750.1 - 5.1e-13 49.3 0.9 6.7e-13 48.9 0.9 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAN11750.1 - 0.005 16.2 0.0 0.015 14.6 0.0 1.8 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_trans_4_4 PF13579.6 GAN11750.1 - 0.0061 17.0 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAN11750.1 - 0.011 15.7 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 GAN11750.1 - 0.12 12.1 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain Adaptin_N PF01602.20 GAN11753.1 - 3.3e-74 250.4 2.3 4.2e-74 250.0 2.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAN11753.1 - 1.8e-60 203.7 2.0 1.8e-60 203.7 2.0 1.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAN11753.1 - 1.3e-13 51.1 0.1 4.3e-08 33.4 0.0 3.5 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 GAN11753.1 - 2.2e-11 43.0 1.2 0.0012 18.9 0.0 4.6 4 0 0 4 4 4 3 HEAT repeat CLASP_N PF12348.8 GAN11753.1 - 0.00018 21.1 0.4 0.0041 16.7 0.0 2.3 1 1 1 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.6 GAN11753.1 - 0.0014 19.0 0.1 0.21 12.1 0.0 3.5 3 1 1 4 4 4 1 HEAT-like repeat Atx10homo_assoc PF09759.9 GAN11753.1 - 0.05 13.6 0.2 0.74 9.9 0.1 2.7 1 1 2 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 GAN11753.1 - 0.074 13.2 0.1 1.7 8.9 0.0 2.6 1 1 2 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 GAN11753.1 - 0.12 12.4 0.4 0.72 9.8 0.1 2.2 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central Globin PF00042.22 GAN11754.1 - 5.9e-07 30.0 0.4 0.0061 17.1 0.0 3.0 3 0 0 3 3 3 2 Globin Ribosomal_S19 PF00203.21 GAN11755.1 - 5.2e-33 112.8 0.4 7e-33 112.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 ACP_syn_III PF08545.10 GAN11755.1 - 0.0045 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FliH PF02108.16 GAN11755.1 - 0.052 13.6 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH PITH PF06201.13 GAN11756.1 - 2e-45 154.7 0.0 2.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Aldo_ket_red PF00248.21 GAN11758.1 - 6.2e-78 262.0 0.0 7e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PIF1 PF05970.14 GAN11759.1 - 1.2e-21 77.4 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase GATase PF00117.28 GAN11759.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Suc_Fer-like PF06999.12 GAN11760.1 - 0.033 14.0 0.0 0.052 13.4 0.0 1.6 1 1 0 1 1 1 0 Sucrase/ferredoxin-like baeRF_family7 PF18849.1 GAN11760.1 - 0.042 14.1 0.6 0.082 13.1 0.6 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 Colicin_im PF03857.13 GAN11762.1 - 0.14 12.1 2.6 0.18 11.7 2.6 1.1 1 0 0 1 1 1 0 Colicin immunity protein DUF4040 PF13244.6 GAN11764.1 - 0.017 15.2 5.4 0.025 14.7 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) RVT_1 PF00078.27 GAN11765.1 - 2.3e-07 30.6 0.0 2.3e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIF_alpha PF05793.12 GAN11767.1 - 3.8 6.0 65.0 4.2 5.8 65.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.10 GAN11767.1 - 4 6.7 57.7 5.5 6.3 57.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Lipase_GDSL PF00657.22 GAN11769.1 - 2.6e-05 24.3 0.1 4.1e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAN11769.1 - 0.007 16.8 0.1 0.014 15.8 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family His_Phos_1 PF00300.22 GAN11770.1 - 6.9e-11 42.2 0.0 1.1e-06 28.5 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zf-CCHC PF00098.23 GAN11771.1 - 7.3e-05 22.7 11.0 0.0082 16.2 1.3 2.8 3 0 0 3 3 3 2 Zinc knuckle Lipoprotein_17 PF04200.12 GAN11771.1 - 0.005 17.2 0.1 0.0094 16.3 0.1 1.5 1 0 0 1 1 1 1 Lipoprotein associated domain zf-C2H2_10 PF16588.5 GAN11771.1 - 0.0057 16.4 2.8 0.0057 16.4 2.8 2.4 2 0 0 2 2 2 1 C2H2 zinc-finger SNAP-25 PF00835.19 GAN11771.1 - 0.036 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 SNAP-25 family zf-CCHC_4 PF14392.6 GAN11771.1 - 0.064 13.0 7.0 0.14 12.0 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF2015 PF09435.10 GAN11772.1 - 1.8e-31 108.3 0.0 2.1e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF3301 PF11743.8 GAN11772.1 - 0.034 13.8 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DUF945 PF06097.11 GAN11772.1 - 0.069 12.2 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) MGC-24 PF05283.11 GAN11773.1 - 5.3 7.5 9.2 6.9 7.1 9.2 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Retrotrans_gag PF03732.17 GAN11774.1 - 0.00015 22.0 0.0 0.00015 22.0 0.0 3.7 3 1 1 4 4 4 1 Retrotransposon gag protein zf-CCHC PF00098.23 GAN11774.1 - 0.00091 19.2 4.4 0.0017 18.4 4.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GAN11774.1 - 0.57 9.9 5.1 1.2 8.9 5.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DDE_Tnp_1_2 PF13586.6 GAN11775.1 - 1e-23 83.5 0.2 3.9e-23 81.6 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain DUF772 PF05598.11 GAN11775.1 - 6.9e-15 54.8 0.0 2.2e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 GAN11775.1 - 0.00082 19.6 0.3 0.019 15.2 0.0 2.7 2 0 0 2 2 2 1 Transposase DDE domain DUF4484 PF14831.6 GAN11775.1 - 0.012 15.7 0.6 0.023 14.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DDE_Tnp_1 PF01609.21 GAN11775.1 - 0.032 13.9 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain GCIP PF13324.6 GAN11775.1 - 0.09 12.4 1.6 0.15 11.7 1.6 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TBCA PF02970.16 GAN11775.1 - 0.74 10.2 0.1 0.74 10.2 0.1 2.5 3 0 0 3 3 3 0 Tubulin binding cofactor A BTB_2 PF02214.22 GAN11777.1 - 1.3e-14 54.3 0.1 2.3e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAN11777.1 - 0.032 14.4 0.1 0.046 14.0 0.1 1.4 1 1 0 1 1 1 0 BTB/POZ domain BTB_3 PF16017.5 GAN11777.1 - 0.095 12.8 0.0 0.38 10.9 0.0 2.0 2 1 0 2 2 2 0 BTB/POZ domain PP2C PF00481.21 GAN11778.1 - 3.6e-13 49.7 0.0 4.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C zf-PARP PF00645.18 GAN11781.1 - 1.5e-16 61.0 0.1 1.5e-16 61.0 0.1 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region LAP1C PF05609.12 GAN11781.1 - 8.3 5.4 28.7 12 4.8 28.7 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Whi5 PF08528.11 GAN11784.1 - 0.00015 21.3 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 Whi5 like DUF4085 PF13315.6 GAN11785.1 - 2.6 7.6 6.5 4.4 6.9 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Exo_endo_phos_2 PF14529.6 GAN11787.1 - 4e-11 42.8 0.0 6.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN11787.1 - 2.4e-06 27.2 0.0 7.4e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YvrJ PF12841.7 GAN11788.1 - 6.6 6.3 10.3 3.9 7.1 2.4 2.4 2 0 0 2 2 2 0 YvrJ protein family SCP2 PF02036.17 GAN11789.1 - 8.5e-11 42.3 2.0 1.5e-10 41.4 2.0 1.4 1 1 0 1 1 1 1 SCP-2 sterol transfer family DAHP_synth_1 PF00793.20 GAN11791.1 - 2.7e-101 338.1 0.0 3.1e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-met PF12874.7 GAN11792.1 - 2.7e-08 33.9 0.1 4.5e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAN11792.1 - 9.3e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 GAN11792.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 U1 zinc finger SNRNP27 PF08648.12 GAN11792.1 - 0.0031 17.6 0.3 0.0031 17.6 0.3 2.6 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf_C2H2_ZHX PF18387.1 GAN11792.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain BCIP PF13862.6 GAN11792.1 - 1.6 8.4 9.5 3.4 7.4 9.5 1.5 1 0 0 1 1 1 0 p21-C-terminal region-binding protein zf-RVT PF13966.6 GAN11793.1 - 5.7e-11 43.0 0.6 1.2e-10 41.9 0.6 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 GAN11795.1 - 1.1e-24 87.2 0.1 3.5e-24 85.6 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1211 PF06736.11 GAN11796.1 - 0.0018 18.7 2.4 0.002 18.5 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1211) Popeye PF04831.13 GAN11796.1 - 3.9 7.6 11.0 5.6 7.1 11.0 1.4 1 0 0 1 1 1 0 Popeye protein conserved region DUF2070 PF09843.9 GAN11796.1 - 4.8 5.4 7.5 4.8 5.3 7.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VIT1 PF01988.19 GAN11798.1 - 0.74 9.6 3.1 0.75 9.6 3.1 1.3 1 0 0 1 1 1 0 VIT family PAT1 PF09770.9 GAN11798.1 - 2.6 6.2 36.1 3.9 5.6 36.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NPR3 PF03666.13 GAN11798.1 - 5.2 5.8 17.3 1.9 7.2 11.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.11 GAN11798.1 - 5.5 6.3 9.6 9.3 5.5 9.6 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Bud13 PF09736.9 GAN11798.1 - 8.7 6.7 20.5 16 5.9 20.5 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Phage_int_SAM_6 PF18644.1 GAN11799.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain Far-17a_AIG1 PF04750.14 GAN11799.1 - 0.034 13.5 8.6 0.042 13.2 8.6 1.2 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein Resolvase PF00239.21 GAN11800.1 - 4.9e-33 114.3 0.1 9.6e-33 113.3 0.1 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 GAN11800.1 - 8.6e-19 67.9 2.8 2.5e-18 66.4 0.3 2.6 2 0 0 2 2 2 1 Recombinase Zn_ribbon_recom PF13408.6 GAN11800.1 - 2.2e-10 40.9 3.1 4.7e-10 39.8 3.1 1.6 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain GSIII_N PF12437.8 GAN11802.1 - 0.027 14.1 0.1 7.3 6.2 0.2 2.5 2 0 0 2 2 2 0 Glutamine synthetase type III N terminal Spt20 PF12090.8 GAN11803.1 - 9.6 5.7 20.7 5.4 6.6 9.7 2.5 2 0 0 2 2 2 0 Spt20 family Exo_endo_phos_2 PF14529.6 GAN11805.1 - 1e-06 28.6 1.2 2.5e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN11805.1 - 0.00029 20.5 0.1 0.00044 19.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HSP70 PF00012.20 GAN11807.1 - 3.3e-125 418.6 7.0 3.8e-125 418.4 7.0 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 GAN11807.1 - 0.0004 20.2 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain eIF3_N PF09440.10 GAN11807.1 - 0.056 13.9 7.1 0.036 14.5 3.0 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF1464 PF07318.12 GAN11807.1 - 0.11 11.6 0.7 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Mito_carr PF00153.27 GAN11808.1 - 1.1e-27 95.8 2.9 4.4e-17 61.8 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein PIF1 PF05970.14 GAN11810.1 - 1.1e-57 195.8 0.1 1.2e-30 106.9 0.0 2.1 1 1 0 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.14 GAN11810.1 - 8.2e-05 20.7 0.0 0.00014 20.0 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 GAN11810.1 - 0.057 13.2 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain MARVEL PF01284.23 GAN11811.1 - 1.9e-08 34.4 14.6 2.9e-08 33.9 14.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 GAN11811.1 - 0.00011 22.0 8.1 0.0016 18.3 8.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF588) DUF3611 PF12263.8 GAN11811.1 - 0.054 13.4 0.3 0.054 13.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) WWE PF02825.20 GAN11813.1 - 0.079 13.6 0.0 0.2 12.3 0.0 1.7 1 0 0 1 1 1 0 WWE domain Pex14_N PF04695.13 GAN11814.1 - 2.7 8.6 12.4 0.2 12.3 4.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_meth_N PF18284.1 GAN11815.1 - 0.13 12.2 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 DNA methylase N-terminal domain zf-CCHC_2 PF13696.6 GAN11816.1 - 0.0059 16.4 1.9 0.0059 16.4 1.9 2.0 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC PF00098.23 GAN11816.1 - 0.039 14.0 0.6 0.039 14.0 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle TDP43_N PF18694.1 GAN11816.1 - 0.13 12.1 0.1 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Zn_Tnp_IS1595 PF12760.7 GAN11816.1 - 0.59 10.2 5.4 1.3 9.0 5.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain SlyX PF04102.12 GAN11819.1 - 0.0067 17.0 0.2 0.0067 17.0 0.2 3.4 2 1 1 3 3 3 2 SlyX FAM76 PF16046.5 GAN11819.1 - 0.26 10.6 23.5 0.028 13.8 16.6 2.1 1 1 1 2 2 2 0 FAM76 protein CoxIIa PF08113.11 GAN11823.1 - 0.73 9.7 3.5 0.56 10.1 0.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family HAMP PF00672.25 GAN11824.1 - 5.9e-47 157.8 14.6 3.4e-09 36.9 0.2 5.9 5 0 0 5 5 5 5 HAMP domain ImcF-related_N PF14331.6 GAN11824.1 - 2.3e-06 27.2 0.3 4.5 6.6 0.0 4.7 2 1 3 5 5 5 2 ImcF-related N-terminal domain HTH_6 PF01418.17 GAN11824.1 - 2e-05 24.5 2.3 18 5.4 0.0 6.2 6 0 0 6 6 5 0 Helix-turn-helix domain, rpiR family DUF1843 PF08898.10 GAN11824.1 - 2.9e-05 24.4 3.3 12 6.5 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) PseudoU_synth_1 PF01416.20 GAN11824.1 - 0.0002 21.8 1.4 27 5.3 0.0 5.0 3 2 1 5 5 5 0 tRNA pseudouridine synthase DUF4731 PF15875.5 GAN11824.1 - 0.0013 18.9 10.1 3.9 7.7 0.1 5.7 5 3 0 5 5 5 2 Domain of unknown function (DUF4731) DUF948 PF06103.11 GAN11824.1 - 0.0018 18.5 43.5 2.3 8.5 0.5 8.3 2 2 4 6 6 6 3 Bacterial protein of unknown function (DUF948) SpoIIID PF12116.8 GAN11824.1 - 0.0019 18.2 1.3 68 3.7 0.0 5.3 5 0 0 5 5 5 0 Stage III sporulation protein D Fib_alpha PF08702.10 GAN11824.1 - 0.012 15.9 8.2 6.8 6.9 0.1 5.1 5 0 0 5 5 5 0 Fibrinogen alpha/beta chain family GrpE PF01025.19 GAN11824.1 - 0.017 14.8 0.0 2 8.1 0.0 3.4 1 1 3 4 4 4 0 GrpE IL32 PF15225.6 GAN11824.1 - 0.04 14.3 0.0 1.2e+02 3.1 0.0 4.8 5 0 0 5 5 5 0 Interleukin 32 DUF1759 PF03564.15 GAN11824.1 - 0.058 13.3 4.2 46 3.9 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1759) TMEM126 PF07114.11 GAN11824.1 - 0.077 12.4 1.7 78 2.6 0.0 3.9 4 0 0 4 4 4 0 Transmembrane protein 126 NusG PF02357.19 GAN11824.1 - 0.11 13.0 2.0 2.9e+02 2.0 0.0 4.8 5 0 0 5 5 5 0 Transcription termination factor nusG WXG100 PF06013.12 GAN11824.1 - 0.17 12.1 11.0 7.3 6.9 0.1 6.1 2 2 5 8 8 8 0 Proteins of 100 residues with WXG Vac_Fusion PF02346.16 GAN11824.1 - 0.22 11.2 4.5 2.6e+02 1.3 0.0 6.2 8 0 0 8 8 8 0 Chordopoxvirus multifunctional envelope protein A27 DUF1725 PF08333.11 GAN11824.1 - 0.3 10.8 11.9 9 6.1 0.3 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1725) DUF3829 PF12889.7 GAN11824.1 - 1.1 8.7 5.8 36 3.7 0.1 3.9 2 1 1 5 5 5 0 Protein of unknown function (DUF3829) VBS PF08913.10 GAN11824.1 - 3.6 8.1 14.3 35 4.9 0.3 4.6 4 1 0 5 5 5 0 Vinculin Binding Site Ubiquitin_4 PF18036.1 GAN11824.1 - 4.9 7.3 10.0 85 3.3 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-like domain OspD PF03207.13 GAN11824.1 - 8 5.7 22.0 6.6 6.0 0.6 4.6 4 1 0 4 4 4 0 Borrelia outer surface protein D (OspD) Ribosomal_L23eN PF03939.13 GAN11825.1 - 7.9e-23 80.4 6.3 1.7e-22 79.4 6.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GAN11825.1 - 3.6e-15 56.1 5.2 7.1e-15 55.1 2.5 2.5 2 1 0 2 2 2 1 Ribosomal protein L23 DUF1323 PF07037.11 GAN11825.1 - 0.019 15.3 0.1 0.84 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) Pre-PUA PF17832.1 GAN11828.1 - 1.4e-26 93.0 0.1 2e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 GAN11828.1 - 6.6e-18 64.4 0.1 1e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 GAN11828.1 - 0.016 15.5 0.2 0.048 14.0 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) RVT_1 PF00078.27 GAN11829.1 - 5.2e-42 143.8 0.0 7.4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 GAN11830.1 - 0.00019 21.4 1.9 0.00019 21.4 1.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 GAN11830.1 - 0.032 13.9 1.3 0.032 13.9 1.3 3.0 3 0 0 3 3 3 0 C2H2 zinc-finger HNH PF01844.23 GAN11830.1 - 1.3 9.3 8.6 4.4 7.5 2.2 2.7 2 0 0 2 2 2 0 HNH endonuclease Alpha_E1_glycop PF01589.16 GAN11831.1 - 0.23 10.1 8.3 0.26 9.9 8.3 1.2 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein zf-C2H2 PF00096.26 GAN11832.1 - 1.4e-06 28.4 18.5 0.00036 20.8 4.8 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAN11832.1 - 0.0015 19.1 3.5 0.91 10.2 0.2 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 GAN11832.1 - 0.022 15.2 4.4 0.022 15.2 4.4 3.9 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 GAN11832.1 - 0.042 14.2 8.9 0.25 11.7 8.1 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon Mito_fiss_reg PF05308.11 GAN11832.1 - 5.7 7.0 7.8 2.3 8.2 3.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator EF-hand_1 PF00036.32 GAN11834.1 - 3.9e-37 123.0 10.7 1.7e-09 36.5 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAN11834.1 - 1.7e-31 108.4 3.7 4.6e-17 62.2 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAN11834.1 - 3.9e-29 98.8 9.9 1.7e-07 30.4 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GAN11834.1 - 7e-29 97.3 7.7 1.3e-08 34.1 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAN11834.1 - 1.8e-26 91.7 11.4 4.3e-15 55.3 0.7 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 GAN11834.1 - 8.4e-14 51.7 0.0 1.5e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAN11834.1 - 3.9e-09 36.4 2.2 0.00021 21.2 0.0 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAN11834.1 - 1.6e-08 34.8 0.1 0.00057 20.2 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 GAN11834.1 - 4.5e-05 23.5 0.6 0.027 14.4 0.2 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 GAN11834.1 - 0.00036 20.6 8.4 0.17 12.1 1.4 3.0 1 1 2 3 3 3 2 Dockerin type I domain EF-hand_11 PF08976.11 GAN11834.1 - 0.00072 20.4 0.0 0.0082 17.0 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 GAN11834.1 - 0.00094 19.5 0.2 0.025 14.9 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain p25-alpha PF05517.12 GAN11834.1 - 0.017 15.3 0.2 1.5 9.0 0.0 2.4 2 1 1 3 3 3 0 p25-alpha DUF2267 PF10025.9 GAN11834.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) SurA_N_3 PF13624.6 GAN11834.1 - 0.099 12.4 0.2 2.7 7.8 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain Lge1 PF11488.8 GAN11834.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF3349 PF11829.8 GAN11834.1 - 0.1 13.4 0.0 11 6.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 GAN11834.1 - 0.15 12.0 0.3 20 5.0 0.0 3.1 1 1 3 4 4 4 0 Caleosin related protein Cyclin PF08613.11 GAN11836.1 - 2.1e-13 51.0 0.2 3.6e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAN11836.1 - 3.6e-08 33.2 0.4 6.6e-08 32.4 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Exo_endo_phos_2 PF14529.6 GAN11839.1 - 2.8e-10 40.1 0.0 6.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAN11839.1 - 0.00027 20.6 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_int_SAM_1 PF02899.17 GAN11840.1 - 0.0041 17.4 0.1 0.0089 16.3 0.1 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 GAN11840.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DDE_Tnp_1 PF01609.21 GAN11842.1 - 2.9e-19 69.6 0.4 2.9e-18 66.3 0.4 2.0 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 GAN11842.1 - 5.6e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 GAN11842.1 - 1e-08 35.4 0.3 2.3e-08 34.3 0.3 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 GAN11842.1 - 0.00037 20.5 0.0 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_assoc PF13808.6 GAN11842.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-associated Chromo PF00385.24 GAN11843.1 - 9.6e-10 38.2 1.6 2.2e-09 37.1 1.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GAN11843.1 - 2.2e-09 37.5 0.1 2.6e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain Adeno_PV PF03910.13 GAN11843.1 - 0.011 14.4 0.2 0.02 13.6 0.2 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV Ribosomal_L28e PF01778.17 GAN11844.1 - 2.8e-41 140.9 2.0 2.8e-41 140.9 2.0 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 GAN11844.1 - 3.5e-29 101.4 23.5 3.5e-29 101.4 23.5 1.9 2 0 0 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.18 GAN11844.1 - 0.029 14.1 1.6 0.048 13.4 1.6 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain DUF4820 PF16091.5 GAN11844.1 - 0.85 8.9 7.5 1.2 8.5 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Rpr2 PF04032.16 GAN11846.1 - 0.00021 21.5 1.8 0.0034 17.6 0.8 2.4 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mito_carr PF00153.27 GAN11847.1 - 0.06 13.3 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial carrier protein Ribosomal_L41 PF05162.13 GAN11848.1 - 0.19 11.8 5.8 0.4 10.8 5.8 1.6 1 0 0 1 1 1 0 Ribosomal protein L41 Bim_N PF06773.11 GAN11849.1 - 0.045 13.4 5.3 0.18 11.5 1.1 2.4 2 1 0 2 2 2 0 Bim protein N-terminus RRP14 PF15459.6 GAN11849.1 - 2.4 8.8 6.1 2.9 8.6 4.2 1.9 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Methyltransf_25 PF13649.6 GAN11852.1 - 4.6e-14 52.9 0.0 2.5e-12 47.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAN11852.1 - 3.2e-11 43.7 0.0 1.3e-07 32.1 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 GAN11852.1 - 6.7e-11 42.3 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAN11852.1 - 1.4e-10 41.1 0.0 5e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAN11852.1 - 1.1e-07 32.1 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 GAN11852.1 - 3e-06 27.9 0.0 1.1e-05 26.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAN11852.1 - 0.00018 21.0 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 GAN11852.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAN11852.1 - 0.0015 17.9 0.1 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 GAN11852.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAN11852.1 - 0.0043 16.4 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_9 PF08003.11 GAN11852.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Dicty_REP PF05086.12 GAN11852.1 - 0.15 10.0 6.5 0.18 9.7 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 GAN11852.1 - 0.2 9.7 8.2 0.26 9.4 8.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Tir_receptor_C PF07489.11 GAN11852.1 - 0.28 11.1 8.9 0.7 9.8 8.9 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SprA-related PF12118.8 GAN11852.1 - 0.64 9.1 7.4 1 8.5 7.4 1.3 1 0 0 1 1 1 0 SprA-related family Mucin PF01456.17 GAN11852.1 - 2.6 8.0 25.6 5.2 7.1 25.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Big_7 PF17957.1 GAN11853.1 - 0.00018 22.2 1.4 0.013 16.2 1.4 2.2 1 1 0 1 1 1 1 Bacterial Ig domain NAR2 PF16974.5 GAN11853.1 - 0.0071 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 High-affinity nitrate transporter accessory CARDB PF07705.11 GAN11853.1 - 0.0089 16.3 0.1 0.014 15.6 0.1 1.4 1 1 0 1 1 1 1 CARDB rve PF00665.26 GAN11855.1 - 1.7e-12 47.6 0.0 3.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 GAN11855.1 - 5.2e-09 35.9 0.4 1.2e-08 34.7 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MLVIN_C PF18697.1 GAN11855.1 - 0.025 14.7 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF5039 PF16442.5 GAN11855.1 - 0.089 12.3 0.4 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) FliD_C PF07195.12 GAN11856.1 - 0.00042 19.8 1.3 0.00063 19.2 1.3 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus HAUS-augmin3 PF14932.6 GAN11856.1 - 0.0048 16.5 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 TPR_MLP1_2 PF07926.12 GAN11856.1 - 0.016 15.2 1.4 0.016 15.2 1.4 1.5 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein DUF1845 PF08900.11 GAN11856.1 - 0.05 13.4 1.6 0.11 12.2 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) HALZ PF02183.18 GAN11856.1 - 0.063 13.5 0.2 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ntox28 PF15605.6 GAN11856.1 - 0.078 13.2 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Bacterial toxin 28 DUF16 PF01519.16 GAN11856.1 - 0.084 13.4 1.4 0.097 13.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 GAN11856.1 - 0.1 12.7 1.4 15 5.8 0.2 2.6 1 1 1 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 GAN11856.1 - 0.13 12.6 5.8 2 8.8 0.4 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 GAN11856.1 - 0.57 10.5 5.5 0.66 10.3 1.7 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF2205 PF10224.9 GAN11856.1 - 0.62 10.1 10.0 0.34 10.9 4.0 2.8 3 1 1 4 4 4 0 Short coiled-coil protein DUF4795 PF16043.5 GAN11856.1 - 0.75 9.4 5.0 1.8 8.1 5.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FlxA PF14282.6 GAN11856.1 - 1 9.4 9.6 0.057 13.4 2.6 2.1 2 0 0 2 2 2 0 FlxA-like protein HSBP1 PF06825.12 GAN11856.1 - 1.5 8.7 5.9 0.41 10.5 2.6 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 GAN11856.1 - 2.1 8.4 8.8 0.33 11.0 4.5 1.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SSTK-IP PF15836.5 GAN11857.1 - 0.073 13.2 1.4 0.3 11.2 1.0 2.0 1 1 1 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein DUF3379 PF11859.8 GAN11859.1 - 0.17 11.2 2.7 0.27 10.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) DUF87 PF01935.17 GAN11861.1 - 3.4e-07 30.6 0.2 1.6e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 GAN11861.1 - 6.3e-05 22.4 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family RT_RNaseH_2 PF17919.1 GAN11862.1 - 1.3e-36 124.6 0.0 3e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAN11862.1 - 3.7e-34 117.2 0.1 1.1e-33 115.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAN11862.1 - 3.9e-29 101.8 0.1 6.5e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YvrJ PF12841.7 GAN11863.1 - 5.4 6.6 6.2 18 4.9 0.4 2.4 2 0 0 2 2 2 0 YvrJ protein family rve_3 PF13683.6 GAN11864.1 - 1.4e-32 111.2 0.2 3e-32 110.2 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 GAN11864.1 - 9e-25 87.2 0.1 8.3e-24 84.1 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain HTH_21 PF13276.6 GAN11864.1 - 2.5e-14 53.2 6.7 4.3e-14 52.4 6.7 1.4 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 GAN11864.1 - 0.00019 21.6 0.1 0.00051 20.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 GAN11864.1 - 0.033 14.8 2.2 0.033 14.8 2.2 3.1 4 0 0 4 4 4 0 Homeodomain-like domain DUF4350 PF14258.6 GAN11864.1 - 0.042 14.3 0.0 4.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) HTH_23 PF13384.6 GAN11864.1 - 0.65 9.9 0.0 0.65 9.9 0.0 3.2 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 GAN11865.1 - 1.1e-22 80.2 0.1 1.3e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 GAN11865.1 - 1.2e-06 28.5 0.1 2.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 GAN11865.1 - 4e-05 23.3 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 GAN11865.1 - 0.00022 21.2 0.0 0.00041 20.3 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 GAN11865.1 - 0.013 15.6 0.3 0.026 14.7 0.3 1.6 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_11 PF08279.12 GAN11865.1 - 0.094 12.7 0.0 0.38 10.7 0.0 1.9 2 1 0 2 2 2 0 HTH domain HTH_32 PF13565.6 GAN11866.1 - 6.4e-05 23.5 0.0 9.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 GAN11866.1 - 9e-05 22.4 0.2 0.0016 18.4 0.2 2.4 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 GAN11866.1 - 0.00019 21.1 0.2 0.0013 18.5 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 GAN11866.1 - 0.00045 20.3 1.2 0.0009 19.3 0.2 2.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 GAN11866.1 - 0.0011 19.2 0.2 0.0018 18.5 0.2 1.5 1 1 0 1 1 1 1 Transposase DUF2315 PF10231.9 GAN11866.1 - 0.015 15.4 0.7 0.02 15.0 0.7 1.3 1 0 0 1 1 1 0 Apoptogenic protein 1 Octopine_DH PF02317.17 GAN11866.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain HTH_Tnp_ISL3 PF13542.6 GAN11866.1 - 0.037 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 GAN11866.1 - 0.074 13.2 0.8 1.8 8.8 0.5 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain RVT_1 PF00078.27 GAN11867.1 - 5.8e-25 88.1 0.0 4.2e-24 85.3 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRPA PF05745.11 GAN11868.1 - 3.3 7.7 8.6 2 8.4 6.9 1.5 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) FeS PF04060.13 GAN11870.1 - 0.078 12.6 2.2 25 4.7 0.0 3.5 3 0 0 3 3 3 0 Putative Fe-S cluster PocR PF10114.9 GAN11870.1 - 0.091 12.5 2.0 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Sensory domain found in PocR RVT_1 PF00078.27 GAN11871.1 - 1.9e-10 40.6 0.0 3.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 GAN11873.1 - 1.5e-05 25.2 0.1 4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein Gag_p24 PF00607.20 GAN11873.1 - 0.075 12.9 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) rve PF00665.26 GAN11876.1 - 6.1e-12 45.8 0.0 1.8e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 GAN11877.1 - 1.1e-34 118.9 0.0 2.7e-34 117.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAN11877.1 - 8.9e-34 115.5 0.0 1.5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Exo_endo_phos PF03372.23 GAN11878.1 - 0.00045 19.8 0.1 0.0019 17.8 0.0 1.9 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAN11878.1 - 0.00068 19.5 0.5 0.00068 19.5 0.5 2.9 3 2 0 3 3 3 1 Endonuclease-reverse transcriptase Syntaxin-6_N PF09177.11 GAN11878.1 - 0.09 13.3 0.3 0.17 12.4 0.3 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Osmo_CC PF08946.10 GAN11878.1 - 1.7 8.9 6.1 16 5.8 0.3 3.0 1 1 1 2 2 2 0 Osmosensory transporter coiled coil DUF4663 PF15668.5 GAN11879.1 - 0.2 10.7 2.2 0.23 10.5 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) LCE6A PF15858.5 GAN11879.1 - 2.8 8.8 7.0 0.67 10.7 3.7 1.6 2 0 0 2 2 2 0 Late cornified envelope protein 6A family HTH_Tnp_Tc3_2 PF01498.18 GAN11882.1 - 0.00013 22.1 0.1 0.00016 21.8 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 GAN11882.1 - 0.0018 18.8 0.0 0.0022 18.5 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 GAN11882.1 - 0.047 13.3 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Retrotran_gag_2 PF14223.6 GAN11883.1 - 0.0021 17.7 0.1 0.0054 16.4 0.1 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Vezatin PF12632.7 GAN11883.1 - 0.047 13.1 0.2 0.22 10.9 0.2 1.9 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes Ribosomal_L24e PF01246.20 GAN11885.1 - 2.1e-31 108.0 7.5 4.7e-31 106.8 7.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-CCHC PF00098.23 GAN11886.1 - 2.3e-06 27.4 16.9 6.9e-05 22.7 5.2 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 GAN11886.1 - 0.012 15.4 0.5 0.038 13.8 0.5 1.9 1 0 0 1 1 1 0 Zinc knuckle ApoO PF09769.9 GAN11886.1 - 0.017 15.1 0.2 0.032 14.2 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein O PHD PF00628.29 GAN11886.1 - 0.28 11.1 8.9 0.56 10.1 8.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-CCHC_2 PF13696.6 GAN11886.1 - 0.63 9.9 18.9 1.2 9.0 7.0 2.4 2 0 0 2 2 2 0 Zinc knuckle CDC73_N PF16050.5 GAN11886.1 - 1.5 8.1 6.1 0.53 9.6 0.4 2.0 1 1 0 2 2 2 0 Paf1 complex subunit CDC73 N-terminal Flavodoxin_2 PF02525.17 GAN11888.1 - 1.6e-24 86.7 0.3 2.8e-24 85.9 0.3 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 GAN11888.1 - 8.4e-08 32.1 0.0 1.8e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase DUF5123 PF17161.4 GAN11888.1 - 0.65 11.1 4.3 3.1 8.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) YvrJ PF12841.7 GAN11894.1 - 0.81 9.3 6.1 4.2 7.0 0.8 2.6 2 0 0 2 2 2 0 YvrJ protein family PRR18 PF15671.5 GAN11896.1 - 1.4 8.7 14.1 1.7 8.4 14.1 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 DUF2981 PF11200.8 GAN11896.1 - 3.5 7.3 9.3 3.8 7.2 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) RVT_1 PF00078.27 GAN11898.1 - 0.054 13.0 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) 4F5 PF04419.14 GAN11900.1 - 1.2e-06 29.3 12.2 1.2e-06 29.3 12.2 1.5 2 0 0 2 2 2 1 4F5 protein family zf-met2 PF12907.7 GAN11900.1 - 2.8e-05 24.1 0.2 4.9e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding zf-C2H2_4 PF13894.6 GAN11900.1 - 0.038 14.8 0.2 0.052 14.4 0.2 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger CDPS PF16715.5 GAN11900.1 - 0.15 11.7 0.6 0.18 11.5 0.6 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF2961 PF11175.8 GAN11901.1 - 0.025 14.3 0.1 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Lip_A_acyltrans PF03279.13 GAN11901.1 - 0.046 12.9 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase DUF2383 PF09537.10 GAN11902.1 - 0.064 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) APC_N_CC PF16689.5 GAN11902.1 - 0.23 11.5 1.5 0.45 10.6 1.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Mcm10 PF09332.11 GAN11902.1 - 6.1 6.2 15.8 0.64 9.4 5.4 2.2 1 1 1 2 2 2 0 Mcm10 replication factor DUF3449 PF11931.8 GAN11904.1 - 0.12 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Csm1_N PF18504.1 GAN11906.1 - 0.0016 18.7 1.3 0.0036 17.6 1.3 1.6 1 0 0 1 1 1 1 Csm1 N-terminal domain Cnn_1N PF07989.11 GAN11906.1 - 0.0069 16.5 2.5 0.013 15.6 2.5 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF4349 PF14257.6 GAN11906.1 - 0.02 14.3 0.7 0.036 13.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Macoilin PF09726.9 GAN11906.1 - 0.027 13.1 1.5 0.032 12.8 1.5 1.1 1 0 0 1 1 1 0 Macoilin family Prp19 PF08606.11 GAN11906.1 - 0.029 14.3 0.2 0.056 13.4 0.2 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like PRKG1_interact PF15898.5 GAN11906.1 - 0.031 15.2 0.7 0.066 14.1 0.7 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain FemAB PF02388.16 GAN11906.1 - 0.064 12.1 1.7 0.098 11.5 1.7 1.2 1 0 0 1 1 1 0 FemAB family DUF1664 PF07889.12 GAN11906.1 - 0.077 13.0 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4297 PF14130.6 GAN11906.1 - 0.11 12.6 0.1 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4297) SKA1 PF07160.12 GAN11906.1 - 0.12 12.2 6.3 0.078 12.8 4.4 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Lipoprotein_20 PF13942.6 GAN11906.1 - 0.22 11.4 4.6 0.36 10.7 4.6 1.3 1 0 0 1 1 1 0 YfhG lipoprotein JIP_LZII PF16471.5 GAN11906.1 - 0.65 10.2 3.0 1.3 9.3 3.0 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF2968 PF11180.8 GAN11906.1 - 0.68 9.6 8.0 1.1 8.8 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF5493 PF17597.2 GAN11907.1 - 0.0019 18.5 0.4 0.002 18.3 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5493) TraG_N PF07916.11 GAN11907.1 - 0.024 13.5 0.6 0.024 13.5 0.6 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Sugar_tr PF00083.24 GAN11909.1 - 3.2e-59 201.0 17.1 8e-57 193.1 17.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAN11909.1 - 4.2e-08 32.5 15.3 2.6e-07 29.9 11.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1863 PF08937.11 GAN11910.1 - 0.021 15.1 0.4 0.029 14.7 0.4 1.3 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) VGLL4 PF15245.6 GAN11910.1 - 0.083 13.0 8.4 0.067 13.3 7.1 1.4 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Med26_C PF15693.5 GAN11910.1 - 0.12 12.5 10.2 0.18 11.9 10.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal BLM10_N PF16547.5 GAN11910.1 - 0.15 12.4 3.4 0.36 11.1 3.4 1.7 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Lin-8 PF03353.15 GAN11910.1 - 0.17 11.4 12.2 0.24 10.9 12.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Senescence_reg PF04520.13 GAN11910.1 - 0.53 11.1 7.9 0.81 10.5 7.9 1.4 1 0 0 1 1 1 0 Senescence regulator DUF5421 PF17458.2 GAN11910.1 - 0.98 8.8 8.6 1.4 8.2 8.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Presenilin PF01080.17 GAN11910.1 - 4.3 6.0 5.5 4.2 6.0 5.5 1.2 1 0 0 1 1 1 0 Presenilin Alpha_E1_glycop PF01589.16 GAN11912.1 - 4.8 5.7 15.0 6.7 5.2 2.6 2.0 1 1 1 2 2 2 0 Alphavirus E1 glycoprotein Csm1_N PF18504.1 GAN11914.1 - 0.00068 19.9 0.4 0.0023 18.2 0.5 1.8 2 0 0 2 2 2 1 Csm1 N-terminal domain FbpA PF05833.11 GAN11914.1 - 0.0096 14.7 0.2 0.016 14.0 0.2 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SKA1 PF07160.12 GAN11914.1 - 0.012 15.4 1.0 0.026 14.4 1.0 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Macoilin PF09726.9 GAN11914.1 - 0.017 13.7 0.7 0.022 13.3 0.7 1.1 1 0 0 1 1 1 0 Macoilin family Prp19 PF08606.11 GAN11914.1 - 0.02 14.8 0.2 0.042 13.9 0.2 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like PRKG1_interact PF15898.5 GAN11914.1 - 0.025 15.5 0.6 0.058 14.3 0.6 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain FemAB PF02388.16 GAN11914.1 - 0.099 11.5 0.9 0.15 10.9 0.9 1.1 1 0 0 1 1 1 0 FemAB family Cnn_1N PF07989.11 GAN11914.1 - 0.16 12.1 2.9 0.3 11.3 2.9 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF2968 PF11180.8 GAN11914.1 - 0.4 10.3 7.6 0.67 9.6 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) JIP_LZII PF16471.5 GAN11914.1 - 0.56 10.4 3.0 1.2 9.3 3.0 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II RVT_1 PF00078.27 GAN11916.1 - 2.7e-06 27.1 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DASH_Hsk3 PF08227.11 GAN11916.1 - 0.31 11.4 2.5 2.1 8.8 1.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like TcdA_TcdB_pore PF12920.7 GAN11921.1 - 0.036 12.3 1.4 0.042 12.1 1.4 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Mad3_BUB1_I_2 PF17014.5 GAN11921.1 - 0.065 13.4 1.0 0.73 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mucor_ambiguus-ASM95059v1/GCA_000950595.1_ASM95059v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mucor_ambiguus-ASM95059v1/GCA_000950595.1_ASM95059v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mucor_ambiguus-ASM95059v1/GCA_000950595.1_ASM95059v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mucor_ambiguus-ASM95059v1/GCA_000950595.1_ASM95059v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 01:34:46 2019 # [ok]