# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2306 PF10067.4 ETS59435.1 - 0.46 10.6 16.0 0.15 12.1 4.9 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2306) ATG22 PF11700.3 ETS59436.1 - 1.2e-40 139.3 19.3 1.8e-40 138.8 13.4 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4184 PF13803.1 ETS59436.1 - 0.0084 15.4 0.5 0.0084 15.4 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4184) Fungal_trans PF04082.13 ETS59438.1 - 1.2e-20 73.4 0.0 2.7e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS59438.1 - 1.2e-09 37.9 11.6 2e-09 37.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 ETS59439.1 - 3.3e-10 40.3 0.1 8.9e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS59439.1 - 5.1e-06 25.2 0.0 0.13 10.7 0.1 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 ETS59439.1 - 0.0051 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.14 ETS59440.1 - 9e-19 67.7 2.2 6.1e-18 64.9 1.5 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS59440.1 - 4.4e-13 48.8 3.7 9.4e-07 28.0 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS59440.1 - 2.8e-05 24.0 0.6 0.00013 21.9 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS59440.1 - 0.00016 20.4 0.3 0.012 14.2 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 ETS59440.1 - 0.00043 19.2 1.9 0.00085 18.2 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 ETS59440.1 - 0.00046 19.3 0.7 0.051 12.6 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 ETS59440.1 - 0.00068 19.5 0.0 0.0028 17.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS59440.1 - 0.0012 17.3 1.0 0.017 13.6 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS59440.1 - 0.0031 16.4 4.5 0.2 10.5 0.3 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.22 ETS59440.1 - 0.012 16.0 0.3 0.33 11.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS59440.1 - 0.013 14.3 0.0 0.033 13.0 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 ETS59440.1 - 0.015 14.4 0.0 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 ETS59440.1 - 0.024 14.6 0.1 0.067 13.2 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS59440.1 - 0.096 11.5 0.1 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS59440.1 - 0.11 11.5 4.0 0.26 10.3 2.8 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 ETS59440.1 - 0.14 11.5 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 ETS59442.1 - 1.5e-25 89.6 39.1 2.4e-24 85.7 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS59442.1 - 2.3e-10 39.6 16.7 2.3e-10 39.6 11.6 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 ETS59442.1 - 3.8e-08 31.9 5.3 6.9e-08 31.1 3.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF848 PF05852.6 ETS59442.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Sugar_tr PF00083.19 ETS59443.1 - 2.5e-85 286.7 17.2 3e-85 286.4 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS59443.1 - 6.9e-20 71.0 34.2 2.2e-16 59.5 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS59443.1 - 0.0021 16.5 24.7 0.0037 15.7 2.1 3.7 2 2 2 4 4 4 2 MFS/sugar transport protein Gln-synt_C PF00120.19 ETS59445.1 - 9.7e-50 169.1 0.0 9.1e-49 165.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Aldedh PF00171.17 ETS59446.1 - 4.1e-129 430.9 0.0 4.6e-129 430.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS59446.1 - 0.00013 20.8 0.0 0.0013 17.5 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short PF00106.20 ETS59447.1 - 8.2e-26 90.8 1.0 1.1e-25 90.4 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS59447.1 - 1.1e-21 77.7 0.0 1.3e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS59447.1 - 8.9e-08 32.0 0.3 1.7e-07 31.0 0.2 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS59447.1 - 0.0017 18.0 0.2 0.0063 16.1 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OPT PF03169.10 ETS59448.1 - 1.7e-135 452.9 49.9 1.9e-135 452.7 34.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_3 PF01494.14 ETS59449.1 - 8.9e-21 74.3 0.0 1.8e-20 73.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS59449.1 - 2.2e-06 26.8 0.1 3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS59449.1 - 3.8e-06 26.0 0.0 5.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS59449.1 - 4e-06 26.7 0.9 9.6e-06 25.5 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS59449.1 - 2.4e-05 24.3 0.2 4.6e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS59449.1 - 0.00042 19.2 2.2 0.0013 17.6 1.1 2.0 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 ETS59449.1 - 0.00065 18.8 0.0 0.00095 18.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS59449.1 - 0.0055 17.0 0.2 0.014 15.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS59449.1 - 0.029 13.0 0.3 0.29 9.6 0.2 2.3 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.11 ETS59449.1 - 0.052 12.9 0.8 9.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 ETS59449.1 - 0.077 13.0 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS59449.1 - 0.08 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 ETS59449.1 - 0.089 11.6 3.5 0.075 11.8 1.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 ETS59449.1 - 0.14 10.5 0.6 0.25 9.7 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.13 ETS59450.1 - 2.8e-10 39.5 1.1 5.6e-10 38.5 0.3 1.6 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS59450.1 - 3.9e-07 29.8 9.6 7.1e-07 29.0 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 ETS59450.1 - 0.48 10.6 7.7 1.2 9.3 5.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region EthD PF07110.6 ETS59451.1 - 2.3e-18 66.8 0.1 4.2e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 EthD domain COesterase PF00135.23 ETS59452.1 - 2.4e-93 313.7 6.7 4e-93 312.9 4.6 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS59452.1 - 9.7e-07 28.5 0.3 4.5e-06 26.3 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS59452.1 - 0.0038 16.4 0.3 0.0088 15.2 0.2 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 ETS59452.1 - 0.0089 14.7 0.0 0.029 13.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS59452.1 - 0.015 15.0 0.2 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS59452.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DNA_pol_A_exo1 PF01612.15 ETS59452.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease ELO PF01151.13 ETS59453.1 - 5.1e-62 209.4 17.8 6.3e-62 209.1 12.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CoA_transf_3 PF02515.12 ETS59454.1 - 1.3e-43 148.4 0.1 2.8e-43 147.3 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III GFO_IDH_MocA PF01408.17 ETS59455.1 - 7.2e-18 65.2 0.0 2e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS59455.1 - 0.00021 21.0 0.0 0.0021 17.8 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Zn_clus PF00172.13 ETS59455.1 - 0.00047 20.0 8.3 0.00047 20.0 5.7 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 ETS59456.1 - 9.2e-78 261.8 23.2 1.2e-77 261.3 16.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS59456.1 - 9.3e-20 70.6 37.4 1.8e-13 49.9 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 ETS59457.1 - 3.7e-11 42.8 0.0 5.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS59457.1 - 1.4e-09 37.9 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS59457.1 - 1.4e-06 28.3 0.0 1.9e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS59457.1 - 0.0094 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Keratin_assoc PF09775.4 ETS59457.1 - 0.044 13.3 0.3 0.063 12.8 0.2 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Acetyltransf_CG PF14542.1 ETS59457.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RAI1 PF08652.6 ETS59458.1 - 5.8e-19 67.6 0.0 1.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease UQ_con PF00179.21 ETS59459.1 - 3.9e-20 71.7 0.0 1.1e-19 70.3 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme TPT PF03151.11 ETS59460.1 - 2.8e-35 121.2 5.3 2.8e-35 121.2 3.7 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 ETS59460.1 - 9.1e-14 51.5 21.5 1.4e-07 31.6 6.8 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 ETS59460.1 - 3.1e-13 49.3 11.1 4.6e-13 48.7 7.7 1.3 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 ETS59460.1 - 7.5e-06 25.2 9.5 0.0004 19.5 0.2 2.9 2 1 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 ETS59460.1 - 0.11 12.7 21.7 0.57 10.3 2.0 3.0 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Plasmod_dom_1 PF09715.5 ETS59460.1 - 0.19 11.6 1.7 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Multi_Drug_Res PF00893.14 ETS59460.1 - 0.28 11.6 6.6 0.093 13.2 1.8 2.2 2 0 0 2 2 2 0 Small Multidrug Resistance protein Orbi_VP6 PF01516.11 ETS59461.1 - 2 7.3 7.2 2.3 7.2 5.0 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 MBOAT_2 PF13813.1 ETS59462.1 - 0.00052 20.0 7.9 0.0018 18.3 0.2 2.8 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family DUF1129 PF06570.6 ETS59462.1 - 0.39 9.9 6.0 1.6 8.0 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ABC_tran PF00005.22 ETS59463.1 - 5.1e-22 78.6 0.0 5.2e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETS59463.1 - 2.2e-07 31.1 0.0 0.079 12.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 ETS59463.1 - 6e-05 22.8 0.0 0.028 14.3 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 ETS59463.1 - 0.0029 17.1 0.4 0.0065 15.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 ETS59463.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETS59463.1 - 0.007 16.0 0.0 0.053 13.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 ETS59463.1 - 0.021 14.2 0.0 0.089 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS59463.1 - 0.029 14.3 2.3 0.1 12.5 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 ETS59463.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 ETS59463.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 ETS59463.1 - 0.12 11.8 0.6 1.5 8.2 0.0 2.3 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 ETS59463.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 ETS59463.1 - 0.21 10.5 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 F_bP_aldolase PF01116.15 ETS59464.1 - 4.4e-70 236.0 0.0 5e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II WD40 PF00400.27 ETS59465.1 - 2.7e-43 144.3 12.7 1e-09 37.8 0.0 10.3 10 0 0 10 10 10 9 WD domain, G-beta repeat Nbas_N PF15492.1 ETS59465.1 - 4.9e-05 22.5 0.3 0.59 9.1 0.0 3.7 3 1 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 ETS59465.1 - 0.00076 18.3 0.1 0.051 12.3 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like RAB3GAP2_N PF14655.1 ETS59465.1 - 0.0092 15.0 0.0 0.79 8.6 0.0 2.6 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3312 PF11768.3 ETS59465.1 - 0.051 11.8 0.0 0.092 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Asp_Glu_race PF01177.17 ETS59467.1 - 1.1e-22 81.0 0.4 1.3e-22 80.7 0.3 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 ETS59467.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 AroM protein FAD_binding_4 PF01565.18 ETS59468.1 - 3.4e-26 91.3 1.6 6.7e-26 90.4 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS59468.1 - 8.5e-13 48.0 0.1 1.6e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS59468.1 - 0.18 10.8 0.1 0.31 10.1 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF1308 PF07000.6 ETS59470.1 - 2e-19 69.4 0.0 1.3e-17 63.5 0.0 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) LCCL PF03815.14 ETS59470.1 - 2.1e-16 59.7 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain ADH_N PF08240.7 ETS59471.1 - 2.3e-22 78.8 3.5 4.8e-22 77.7 2.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS59471.1 - 4.6e-17 61.7 0.0 1e-15 57.4 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS59471.1 - 0.00028 20.1 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS59471.1 - 0.00079 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETS59471.1 - 0.001 18.5 0.0 0.0026 17.1 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 ETS59471.1 - 0.0082 16.2 0.0 0.025 14.6 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 ETS59471.1 - 0.023 14.2 0.1 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 ETS59471.1 - 0.062 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 ETS59471.1 - 0.099 12.4 1.4 0.15 11.8 0.3 1.8 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.11 ETS59472.1 - 5.3e-16 58.2 74.6 7e-12 44.7 31.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 ETS59473.1 - 2.6e-06 27.3 0.0 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS59473.1 - 2.8e-06 27.3 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS59473.1 - 0.00019 21.4 0.1 0.0006 19.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS59473.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 ETS59473.1 - 0.05 13.4 0.1 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C3HC4_2 PF13923.1 ETS59474.1 - 5.6e-07 29.4 14.2 1.1e-06 28.5 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS59474.1 - 4.3e-06 26.2 7.7 7e-06 25.6 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS59474.1 - 0.0007 19.1 11.6 0.0011 18.5 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS59474.1 - 0.0012 18.5 13.6 0.0026 17.5 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS59474.1 - 0.072 12.8 9.7 0.12 12.1 6.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 ETS59474.1 - 0.42 10.7 11.0 1.4 9.1 7.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger dCMP_cyt_deam_1 PF00383.17 ETS59475.1 - 1.2e-08 34.5 0.0 3.5e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF3135 PF11333.3 ETS59475.1 - 0.048 13.8 0.4 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) 4HB_MCP_1 PF12729.2 ETS59475.1 - 0.051 12.9 0.3 0.081 12.2 0.2 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction MCM PF00493.18 ETS59475.1 - 0.069 11.9 0.2 0.096 11.4 0.2 1.1 1 0 0 1 1 1 0 MCM2/3/5 family Cep57_MT_bd PF06657.8 ETS59475.1 - 0.26 11.2 2.0 6.4 6.7 0.5 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pirin PF02678.11 ETS59476.1 - 3.8e-28 97.4 0.1 8.6e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 ETS59476.1 - 1.8e-23 82.5 0.1 2.4e-22 78.9 0.0 2.5 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 ETS59476.1 - 0.0016 17.8 2.9 0.007 15.8 1.1 2.6 3 0 0 3 3 3 1 Cupin domain zf-C2H2 PF00096.21 ETS59477.1 - 4.5e-07 29.8 8.1 0.00073 19.7 0.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS59477.1 - 3.2e-05 23.9 8.1 0.042 14.1 0.5 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3493 PF11998.3 ETS59477.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3493) zf-H2C2_2 PF13465.1 ETS59477.1 - 0.003 17.7 0.3 0.003 17.7 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETS59477.1 - 0.0049 16.7 0.4 0.015 15.1 0.3 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger adh_short PF00106.20 ETS59478.1 - 1.1e-27 97.0 0.1 5e-27 94.8 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS59478.1 - 9.8e-10 38.6 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS59478.1 - 9.3e-07 28.6 0.4 4.7e-06 26.3 0.3 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS59478.1 - 1e-05 25.6 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS59478.1 - 8.5e-05 22.0 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS59478.1 - 0.00051 18.8 0.1 0.00078 18.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 ETS59478.1 - 0.0048 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 ETS59478.1 - 0.039 12.8 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3842 PF12953.2 ETS59478.1 - 0.17 12.0 0.7 0.56 10.3 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3842) Methyltransf_11 PF08241.7 ETS59479.1 - 8.5e-18 64.6 0.0 2.9e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS59479.1 - 3.2e-09 37.0 0.0 8.7e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS59479.1 - 2e-08 34.6 0.0 8.6e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS59479.1 - 2.5e-08 34.4 0.0 4.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS59479.1 - 2.7e-08 33.6 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS59479.1 - 2.1e-07 30.6 0.0 9.3e-07 28.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS59479.1 - 2e-06 27.7 0.0 5.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS59479.1 - 2e-05 23.8 0.0 4.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF4210 PF13915.1 ETS59480.1 - 2e-20 72.8 0.1 5.9e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 ETS59480.1 - 1.5e-16 60.0 0.5 6.7e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 Chromosome segregation during meiosis Sulfate_transp PF00916.15 ETS59482.1 - 3.7e-76 255.8 7.1 3.7e-76 255.8 4.9 2.0 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 ETS59482.1 - 9.3e-32 108.5 2.4 9.3e-32 108.5 1.6 3.1 2 1 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 ETS59482.1 - 1e-10 41.0 0.0 2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain PGPGW PF09656.5 ETS59485.1 - 0.13 11.5 1.0 0.24 10.7 0.7 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Ion_trans_2 PF07885.11 ETS59487.1 - 3.1e-31 106.9 29.6 4.4e-16 58.3 6.3 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 ETS59487.1 - 0.0024 17.1 12.6 0.096 11.9 2.4 2.6 2 1 0 2 2 2 2 Ion transport protein AIP3 PF03915.8 ETS59487.1 - 0.047 12.5 0.8 0.14 10.9 0.5 1.7 1 0 0 1 1 1 0 Actin interacting protein 3 ADK PF00406.17 ETS59488.1 - 1.4e-46 158.0 0.0 1.8e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 ETS59488.1 - 1.3e-13 50.3 0.0 2.4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 ETS59488.1 - 1.6e-08 35.4 0.0 3.2e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS59488.1 - 2.4e-05 24.2 0.1 0.00038 20.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS59488.1 - 6.1e-05 23.3 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 ETS59488.1 - 0.032 13.6 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 ETS59488.1 - 0.046 12.8 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin adh_short PF00106.20 ETS59489.1 - 8.7e-29 100.5 2.7 1.1e-28 100.2 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS59489.1 - 9.8e-21 74.6 0.0 1.3e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS59489.1 - 1.7e-13 50.6 1.3 2.2e-13 50.2 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS59489.1 - 0.0001 21.8 0.1 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_28 PF03033.15 ETS59489.1 - 0.006 16.3 0.3 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Eno-Rase_NADH_b PF12242.3 ETS59489.1 - 0.014 15.1 0.7 0.028 14.2 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 ETS59489.1 - 0.22 11.4 5.6 1.7 8.6 3.9 2.3 1 1 0 1 1 1 0 NADH(P)-binding SR-25 PF10500.4 ETS59490.1 - 0.083 12.3 12.6 0.1 12.0 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 ETS59490.1 - 0.82 9.7 13.3 1 9.4 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Aldo_ket_red PF00248.16 ETS59492.1 - 1.8e-47 161.5 0.0 2.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fe-ADH PF00465.14 ETS59493.1 - 9.7e-92 307.4 0.0 1.5e-91 306.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETS59493.1 - 9.8e-12 44.7 0.0 2.5e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Abhydrolase_5 PF12695.2 ETS59493.1 - 0.0039 16.9 0.1 0.012 15.3 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family MAPEG PF01124.13 ETS59494.1 - 1.8e-11 43.7 6.9 2.3e-11 43.4 4.7 1.2 1 0 0 1 1 1 1 MAPEG family HupE_UreJ_2 PF13795.1 ETS59494.1 - 0.11 11.9 1.8 1.4 8.4 0.9 2.0 1 1 1 2 2 2 0 HupE / UreJ protein AMP-binding PF00501.23 ETS59495.1 - 1.5e-70 237.6 0.3 1.9e-70 237.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS59495.1 - 1.3e-16 61.2 0.1 4.6e-16 59.5 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_GDSL_2 PF13472.1 ETS59496.1 - 8.2e-23 81.4 0.3 1e-22 81.1 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS59496.1 - 1.2e-07 31.7 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 ETS59496.1 - 0.043 13.5 0.1 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MS_channel PF00924.13 ETS59497.1 - 3.2e-22 78.9 1.4 5.7e-22 78.0 1.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 ETS59497.1 - 0.0028 16.8 0.3 0.0051 16.0 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETS59497.1 - 0.0044 17.1 0.1 0.018 15.1 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETS59497.1 - 0.018 14.8 0.1 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain DUF4328 PF14219.1 ETS59497.1 - 3.6 6.8 20.6 0.26 10.5 9.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4328) IQ PF00612.22 ETS59503.1 - 7.3e-05 22.0 0.3 0.00018 20.8 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Urm1 PF09138.6 ETS59504.1 - 2.7e-35 120.3 0.0 3.1e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 ETS59504.1 - 3.3e-06 27.4 0.0 4.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family DUF3290 PF11694.3 ETS59504.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Glyco_hydro_47 PF01532.15 ETS59505.1 - 4.7e-152 506.7 0.0 5.6e-152 506.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CHCH PF06747.8 ETS59507.1 - 0.00081 19.2 4.1 0.015 15.2 0.4 2.9 2 1 1 3 3 3 2 CHCH domain UCR_hinge PF02320.11 ETS59507.1 - 0.0012 18.7 6.1 0.0034 17.2 0.4 2.5 2 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 ETS59507.1 - 0.079 12.9 5.8 0.88 9.6 0.2 2.4 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 ETS59507.1 - 0.11 12.3 8.7 0.45 10.3 1.0 3.0 1 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 ETS59507.1 - 0.37 10.9 4.0 5.5 7.1 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3128) COX17 PF05051.8 ETS59507.1 - 0.56 10.2 3.1 11 6.1 0.3 2.5 1 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF1903 PF08991.5 ETS59507.1 - 3 8.0 9.8 5.8 7.1 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1903) zf-C2HC5 PF06221.8 ETS59508.1 - 4.9e-14 51.8 2.8 7.8e-14 51.1 1.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF902 PF06001.8 ETS59508.1 - 0.93 9.6 3.0 1.5 9.0 2.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) DZR PF12773.2 ETS59508.1 - 1 9.2 4.0 2 8.2 2.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon SR-25 PF10500.4 ETS59508.1 - 8.4 5.7 11.5 0.57 9.6 0.3 2.7 2 2 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-DHHC PF01529.15 ETS59509.1 - 6.7e-31 107.0 0.0 2.9e-29 101.6 0.0 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase DctQ PF04290.7 ETS59509.1 - 4.4 7.0 17.4 4.2 7.1 5.1 2.8 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component His_Phos_2 PF00328.17 ETS59510.1 - 1.2e-18 67.6 0.0 2.1e-18 66.7 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aa_trans PF01490.13 ETS59511.1 - 1.8e-78 263.8 12.9 2.3e-78 263.5 8.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF754 PF05449.6 ETS59511.1 - 0.13 12.3 3.6 5.7 7.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF754) YfhO PF09586.5 ETS59511.1 - 0.24 9.4 5.2 0.43 8.5 3.6 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO IMS PF00817.15 ETS59512.1 - 2.5e-38 131.1 0.0 9.6e-38 129.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 ETS59512.1 - 1.5e-14 54.0 0.0 4e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 ETS59512.1 - 3e-06 27.1 7.9 0.13 12.1 0.2 4.1 2 2 1 3 3 3 3 Domain of unknown function (DUF4414) BRCT PF00533.21 ETS59512.1 - 7.3e-05 22.8 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 ETS59512.1 - 0.0016 18.3 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.6 ETS59512.1 - 0.078 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) stn_TNFRSF12A PF12191.3 ETS59513.1 - 0.059 13.3 0.6 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain FAM91_C PF14648.1 ETS59514.1 - 0.034 12.9 0.0 0.04 12.7 0.0 1.0 1 0 0 1 1 1 0 FAM91 C-terminus PALP PF00291.20 ETS59515.1 - 1.5e-46 159.0 0.0 1.2e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme DUF1049 PF06305.6 ETS59515.1 - 0.18 11.3 0.6 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TFR_dimer PF04253.10 ETS59516.1 - 1.8e-13 50.1 0.0 3.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 ETS59516.1 - 2.9e-13 49.9 0.3 5.2e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS59516.1 - 5.3e-10 38.9 0.5 1.2e-09 37.8 0.4 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 ETS59516.1 - 0.0025 17.3 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Phage_int_SAM_1 PF02899.12 ETS59516.1 - 0.061 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Nicastrin PF05450.10 ETS59516.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Mito_carr PF00153.22 ETS59517.1 - 2e-55 184.4 4.6 1.4e-19 69.5 0.2 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Vac14_Fig4_bd PF11916.3 ETS59517.1 - 0.045 12.8 0.0 0.13 11.3 0.0 1.7 1 1 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Bac_luciferase PF00296.15 ETS59518.1 - 3.8e-66 223.3 4.1 5.2e-66 222.8 2.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Trehalase PF01204.13 ETS59520.1 - 3.2e-116 388.9 2.2 3.8e-105 352.4 0.0 2.2 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 ETS59520.1 - 6.5e-05 21.8 0.3 0.0011 17.7 0.0 2.1 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase DFF-C PF09033.5 ETS59520.1 - 0.042 13.6 0.6 0.088 12.6 0.0 1.8 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain DUF566 PF04484.7 ETS59520.1 - 4.3 6.7 11.5 7.6 5.9 8.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) PNK3P PF08645.6 ETS59521.1 - 2.6e-45 153.6 0.0 3.8e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 ETS59521.1 - 6.8e-31 107.0 1.2 1.5e-30 105.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS59521.1 - 3.8e-06 26.1 0.2 0.07 12.2 0.0 2.5 3 0 0 3 3 3 2 Zeta toxin KTI12 PF08433.5 ETS59521.1 - 0.011 14.9 1.6 0.2 10.8 0.3 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 ETS59521.1 - 0.023 14.1 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS59521.1 - 0.033 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS59521.1 - 0.042 14.6 0.0 0.085 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS59521.1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 ETS59521.1 - 0.12 11.4 0.3 13 4.8 0.1 2.2 1 1 1 2 2 2 0 6-phosphofructo-2-kinase Mg_chelatase PF01078.16 ETS59521.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G_glu_transpept PF01019.16 ETS59522.1 - 3.5e-147 490.9 0.3 4e-147 490.7 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ACOX PF01756.14 ETS59523.1 - 5.3e-39 133.5 0.4 1e-38 132.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 ETS59523.1 - 1.5e-23 83.4 0.2 3e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 ETS59523.1 - 1e-11 44.1 0.4 2.8e-11 42.7 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 ETS59523.1 - 0.0002 21.4 0.6 0.018 15.1 0.3 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.13 ETS59525.1 - 4e-06 26.6 11.0 6.7e-06 25.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 ETS59526.1 - 2.5e-15 56.3 1.5 4.8e-15 55.4 1.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 AMP-binding PF00501.23 ETS59526.1 - 2e-07 29.7 0.0 3.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PAN_4 PF14295.1 ETS59528.1 - 0.00043 19.9 0.6 0.0011 18.6 0.4 1.7 1 0 0 1 1 1 1 PAN domain Methyltransf_18 PF12847.2 ETS59529.1 - 3.4e-06 27.5 0.0 7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS59529.1 - 9.4e-06 26.0 0.0 2.2e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS59529.1 - 9.6e-06 25.4 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS59529.1 - 4.4e-05 23.8 0.0 0.00037 20.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.12 ETS59529.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Lin0512_fam PF09585.5 ETS59529.1 - 0.072 12.6 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) Methyltransf_26 PF13659.1 ETS59529.1 - 0.098 12.6 0.4 0.84 9.6 0.3 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 ETS59529.1 - 0.11 12.1 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.19 ETS59531.1 - 1.2e-106 357.0 17.9 1.5e-106 356.6 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS59531.1 - 1.3e-19 70.1 38.1 1.3e-16 60.2 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AgrB PF04647.10 ETS59531.1 - 0.039 13.0 0.1 0.039 13.0 0.0 3.1 3 0 0 3 3 3 0 Accessory gene regulator B YqhR PF11085.3 ETS59531.1 - 0.068 12.6 0.0 0.068 12.6 0.0 2.8 3 0 0 3 3 3 0 Conserved membrane protein YqhR Pox_A14 PF05767.7 ETS59531.1 - 0.52 10.2 0.0 0.52 10.2 0.0 3.2 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Glyco_hydro_42 PF02449.10 ETS59534.1 - 3.4e-116 388.4 4.9 4.4e-116 388.0 3.4 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.5 ETS59534.1 - 1.1e-34 119.3 0.0 2.1e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42C PF08533.5 ETS59534.1 - 0.0017 17.7 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Cellulase PF00150.13 ETS59534.1 - 0.0043 16.3 0.3 0.012 14.8 0.2 1.7 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 ETS59534.1 - 0.02 14.2 0.5 0.13 11.6 0.4 2.1 1 1 0 1 1 1 0 Glycosyl hydrolases family 35 DUF4434 PF14488.1 ETS59534.1 - 0.026 14.2 0.4 0.17 11.5 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Na_H_Exchanger PF00999.16 ETS59535.1 - 1.8e-40 138.6 16.9 2.5e-40 138.2 11.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GRASP55_65 PF04495.9 ETS59536.1 - 7.1e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 ETS59536.1 - 3.2e-05 23.7 0.0 6.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 ETS59536.1 - 0.00076 19.6 0.1 0.0036 17.4 0.0 2.1 1 1 1 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Abhydrolase_6 PF12697.2 ETS59537.1 - 5.9e-12 45.9 0.0 1.4e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS59537.1 - 0.0009 19.0 0.0 0.0058 16.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS59537.1 - 0.039 13.4 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAM176 PF14851.1 ETS59539.1 - 0.15 11.7 4.3 0.18 11.4 2.4 1.5 1 1 0 1 1 1 0 FAM176 family SR-25 PF10500.4 ETS59539.1 - 1.2 8.5 24.7 0.078 12.4 11.0 2.5 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Bap31 PF05529.7 ETS59539.1 - 1.6 8.1 8.6 2.6 7.4 6.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Chromate_transp PF02417.10 ETS59540.1 - 1.6e-52 177.5 33.3 1.5e-27 96.2 4.9 3.8 3 1 1 4 4 4 2 Chromate transporter DUF2635 PF10948.3 ETS59541.1 - 0.075 12.3 0.1 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Acetyltransf_3 PF13302.1 ETS59542.1 - 2.1e-08 34.4 0.0 2.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS59542.1 - 1.8e-07 31.0 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETS59542.1 - 0.00035 20.4 0.1 0.00049 20.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS59542.1 - 0.00085 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 ETS59542.1 - 0.0048 16.8 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS59542.1 - 0.012 15.7 0.1 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 ETS59542.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HPP PF04982.8 ETS59543.1 - 5.2e-38 129.5 4.9 7.8e-38 129.0 3.4 1.3 1 0 0 1 1 1 1 HPP family p450 PF00067.17 ETS59545.1 - 5e-68 229.7 0.0 6.9e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.16 ETS59547.1 - 2.3e-10 40.2 13.4 6.1e-07 29.2 3.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 ETS59547.1 - 6.9e-08 32.0 3.7 1.9e-07 30.7 2.5 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 ETS59547.1 - 1.6 8.6 15.4 0.14 11.9 2.1 2.8 3 0 0 3 3 3 0 Basic region leucine zipper Peptidase_S64 PF08192.6 ETS59548.1 - 3 6.0 12.2 3.8 5.7 8.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 SCF PF02404.10 ETS59548.1 - 3.4 6.7 5.1 1.4 8.0 1.1 1.8 1 1 1 2 2 2 0 Stem cell factor Mcm10 PF09332.6 ETS59548.1 - 7.2 5.8 9.3 3.7 6.7 4.9 1.5 1 1 0 1 1 1 0 Mcm10 replication factor NAD_binding_2 PF03446.10 ETS59549.1 - 1.2e-34 119.5 0.4 1.6e-34 119.0 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS59549.1 - 4.7e-30 104.1 0.3 1.9e-29 102.1 0.0 2.1 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 ETS59549.1 - 0.024 15.0 0.4 0.15 12.5 0.2 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Coiled PF05710.7 ETS59549.1 - 0.043 14.2 1.1 0.11 12.9 0.5 1.9 1 1 0 1 1 1 0 Coiled coil Ribonuclease_3 PF00636.21 ETS59550.1 - 6.3e-15 55.6 0.0 2.4e-14 53.7 0.0 2.1 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 ETS59550.1 - 0.021 14.7 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease-III-like DUF1839 PF08893.5 ETS59550.1 - 0.061 12.2 0.1 0.21 10.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1839) DnaJ_CXXCXGXG PF00684.14 ETS59552.1 - 0.19 11.8 6.1 0.59 10.2 0.7 2.4 2 0 0 2 2 2 0 DnaJ central domain Metallophos PF00149.23 ETS59554.1 - 2.8e-24 85.6 0.1 4.1e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 ETS59554.1 - 1.1e-15 57.4 0.1 2.3e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 ETS59554.1 - 1.5e-08 33.6 0.6 2.3e-08 33.0 0.4 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 ETS59554.1 - 0.00045 20.0 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MRF_C2 PF13888.1 ETS59554.1 - 0.013 15.3 0.3 0.029 14.1 0.2 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 Prefoldin PF02996.12 ETS59557.1 - 3.7e-11 42.7 0.3 6.3e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit FliD_N PF02465.13 ETS59557.1 - 0.016 15.5 1.9 0.065 13.6 0.1 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ATG16 PF08614.6 ETS59557.1 - 0.019 14.7 3.0 0.033 14.0 2.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Trp_syntA PF00290.15 ETS59557.1 - 0.072 11.6 0.0 0.11 10.9 0.0 1.3 1 1 0 1 1 1 0 Tryptophan synthase alpha chain TFIID_90kDa PF04494.10 ETS59557.1 - 0.32 11.0 1.6 0.4 10.7 0.2 1.8 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit BLOC1_2 PF10046.4 ETS59557.1 - 0.6 10.2 3.4 10 6.3 0.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MerR-DNA-bind PF09278.6 ETS59557.1 - 5 7.6 7.4 10 6.5 0.5 2.9 2 1 0 2 2 2 0 MerR, DNA binding Complex1_LYR PF05347.10 ETS59558.1 - 2.3e-09 36.8 0.7 3.5e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS59558.1 - 4.6e-07 29.9 0.8 9.2e-07 28.9 0.0 1.8 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 ETS59558.1 - 0.0042 17.5 0.0 0.0071 16.8 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like adh_short PF00106.20 ETS59559.1 - 7.4e-20 71.5 0.3 1.6e-19 70.4 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS59559.1 - 2.3e-18 66.8 0.0 3.5e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS59559.1 - 7.8e-05 22.4 0.1 0.00013 21.6 0.0 1.4 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 ETS59559.1 - 0.014 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AA_kinase PF00696.23 ETS59559.1 - 0.067 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family DUF2985 PF11204.3 ETS59560.1 - 9.8e-26 89.3 0.9 9.8e-26 89.3 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) TraY PF05509.6 ETS59561.1 - 8.2 6.2 7.3 1.1 9.0 1.8 1.9 2 0 0 2 2 2 0 TraY domain Asp PF00026.18 ETS59562.1 - 6.9e-55 186.5 12.0 1.5e-54 185.4 8.3 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS59562.1 - 1.1e-06 28.7 4.0 1.1e-06 28.7 2.8 3.3 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS59562.1 - 5.5e-05 23.5 0.7 0.0056 17.1 0.1 2.9 2 0 0 2 2 2 1 Aspartyl protease PseudoU_synth_2 PF00849.17 ETS59563.1 - 3.5e-25 88.7 0.0 7.3e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Methyltransf_26 PF13659.1 ETS59563.1 - 5.7e-16 58.6 0.1 1.6e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETS59563.1 - 2.2e-14 53.4 0.0 4.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 ETS59563.1 - 3.6e-06 26.6 0.0 7.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.3 ETS59563.1 - 0.00044 19.3 0.0 0.056 12.4 0.0 2.3 1 1 1 2 2 2 2 RRNA methyltransferase AviRa Methyltransf_18 PF12847.2 ETS59563.1 - 0.0017 18.8 0.0 0.0042 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS59563.1 - 0.03 14.0 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.10 ETS59564.1 - 8.4e-11 41.5 0.5 1.4e-10 40.8 0.1 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS59564.1 - 6.2e-09 35.9 0.3 1.3e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 ETS59564.1 - 9e-06 26.1 0.9 1.9e-05 25.0 0.1 1.8 1 1 1 2 2 2 1 Complex1_LYR-like His_Phos_2 PF00328.17 ETS59565.1 - 1.9e-24 86.6 0.0 2.5e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Hexokinase_2 PF03727.11 ETS59566.1 - 1.6e-73 246.8 0.1 2.3e-73 246.4 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 ETS59566.1 - 6.9e-68 228.0 0.0 9.8e-68 227.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Epimerase PF01370.16 ETS59567.1 - 1.1e-22 80.7 0.0 1.7e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS59567.1 - 3.1e-12 45.7 0.0 1.9e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS59567.1 - 2.4e-10 39.7 0.1 2.4e-09 36.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS59567.1 - 2.5e-08 34.1 0.0 7.3e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS59567.1 - 1.5e-07 30.5 0.0 4.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 ETS59567.1 - 0.00073 18.6 0.1 0.00097 18.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 ETS59567.1 - 0.0015 18.4 0.1 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ETS59567.1 - 0.018 14.2 0.0 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 ETS59567.1 - 0.044 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 ETS59567.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rubis-subs-bind PF09273.6 ETS59568.1 - 0.00062 19.6 0.1 0.0081 16.0 0.0 2.5 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 ETS59568.1 - 0.018 15.3 0.0 0.15 12.3 0.0 2.3 1 1 0 1 1 1 0 SET domain MIP PF00230.15 ETS59569.1 - 2.5e-22 79.4 9.8 3.8e-22 78.8 6.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein Rod-binding PF10135.4 ETS59569.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Rod binding protein Pkinase PF00069.20 ETS59570.1 - 3.2e-39 134.6 0.0 1.5e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS59570.1 - 8.3e-16 57.8 0.0 3.6e-11 42.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS59570.1 - 3.5e-05 22.9 0.0 0.016 14.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETS59570.1 - 0.035 13.8 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 ETS59571.1 - 2e-22 79.8 0.6 1e-20 74.2 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS59571.1 - 1.8e-11 43.9 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS59571.1 - 2e-11 44.1 0.2 2.6e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS59571.1 - 1.4e-07 30.9 0.4 3.9e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 ETS59571.1 - 0.00062 18.6 0.0 0.0017 17.1 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 ETS59571.1 - 0.011 15.1 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.9 ETS59571.1 - 0.015 14.4 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase Esterase_phd PF10503.4 ETS59571.1 - 0.022 14.0 0.0 0.41 9.8 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF202 PF02656.10 ETS59572.1 - 7.7e-05 22.8 1.3 0.0021 18.2 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF202) RCC1 PF00415.13 ETS59574.1 - 5.6e-14 52.0 20.1 0.032 14.4 0.1 8.3 7 3 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS59574.1 - 3.7e-10 39.1 21.0 0.00057 19.4 0.7 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Sigma70_r4_2 PF08281.7 ETS59574.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Pyr_redox_2 PF07992.9 ETS59575.1 - 7.7e-25 87.9 0.0 6.5e-16 58.8 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS59575.1 - 1.2e-12 48.0 0.0 1e-11 45.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS59575.1 - 0.001 19.2 0.1 0.06 13.3 0.0 3.2 3 2 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS59575.1 - 0.072 13.3 0.1 2.4 8.4 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding C9orf72-like PF15019.1 ETS59576.1 - 0.0048 16.1 0.0 0.0077 15.4 0.0 1.2 1 0 0 1 1 1 1 C9orf72-like protein family Acetyltransf_3 PF13302.1 ETS59577.1 - 1.6e-20 73.7 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS59577.1 - 3.2e-10 40.1 0.0 4.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS59577.1 - 0.0061 16.5 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AstA PF04958.7 ETS59577.1 - 0.028 12.8 0.0 0.038 12.4 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit C2 PF00168.25 ETS59578.1 - 1.2e-18 66.7 0.0 6.7e-14 51.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain zf-TRAF PF02176.13 ETS59579.1 - 6.3e-09 36.0 15.2 5.4e-07 29.8 1.4 5.3 3 1 3 7 7 7 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 ETS59579.1 - 3.2e-07 30.2 8.9 3.2e-07 30.2 6.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS59579.1 - 4.8e-07 29.5 10.6 4.8e-07 29.5 7.3 3.3 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 ETS59579.1 - 3.6e-06 26.6 9.4 3.6e-06 26.6 6.5 2.9 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS59579.1 - 0.00039 20.0 9.1 0.00039 20.0 6.3 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 ETS59579.1 - 0.00046 19.6 4.9 0.00046 19.6 3.4 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETS59579.1 - 0.005 16.5 4.0 0.005 16.5 2.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 ETS59579.1 - 0.0052 16.4 7.2 0.0052 16.4 5.0 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 ETS59579.1 - 1.1 8.9 20.7 0.28 10.8 1.1 4.0 1 1 3 4 4 4 0 Seven in absentia protein family Aa_trans PF01490.13 ETS59580.1 - 1.6e-61 208.0 11.1 2e-61 207.7 7.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 ETS59580.1 - 0.00031 19.6 9.5 0.00031 19.6 6.6 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Herpes_pp85 PF04637.7 ETS59580.1 - 0.12 10.6 1.4 0.26 9.5 1.0 1.5 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Peptidase_M20 PF01546.23 ETS59582.1 - 4.1e-33 114.4 0.0 7.5e-33 113.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS59582.1 - 1e-11 44.5 0.0 2.7e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Sedlin_N PF04628.8 ETS59583.1 - 1.9e-35 121.6 0.0 2.2e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_7 PF03441.9 ETS59584.1 - 1.3e-87 293.5 0.0 1.8e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS59584.1 - 1.1e-38 132.5 0.1 2e-38 131.7 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase MMgT PF10270.4 ETS59585.1 - 3.8e-24 85.1 0.2 4.2e-24 85.0 0.1 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter AA_permease_2 PF13520.1 ETS59586.1 - 1.1e-55 188.9 55.8 1.3e-55 188.6 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS59586.1 - 5.7e-33 113.9 50.2 7.4e-33 113.6 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease INTS5_N PF14837.1 ETS59586.1 - 0.082 12.3 0.3 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus DUF4342 PF14242.1 ETS59586.1 - 0.25 11.1 1.5 5 6.9 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF2614 PF11023.3 ETS59586.1 - 4.2 7.1 6.5 6.6 6.5 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2614) ABC_tran PF00005.22 ETS59587.1 - 5.7e-43 146.4 0.3 1.2e-21 77.4 0.0 4.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 ETS59587.1 - 1.5e-16 61.2 0.0 2.1e-06 27.9 0.0 3.5 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 ETS59587.1 - 1.3e-11 44.2 0.0 0.00015 21.1 0.0 3.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS59587.1 - 7e-10 38.2 0.3 0.00049 19.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS59587.1 - 1.8e-07 31.7 7.5 0.0013 19.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS59587.1 - 4.9e-07 29.0 0.5 0.012 14.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS59587.1 - 9.5e-07 28.7 0.0 0.0045 16.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 ETS59587.1 - 2.3e-06 27.3 0.0 0.031 13.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 ETS59587.1 - 4.8e-06 26.6 8.6 0.0016 18.4 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 ETS59587.1 - 1.5e-05 25.1 0.0 0.057 13.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS59587.1 - 4.3e-05 24.3 4.7 0.028 15.2 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 ETS59587.1 - 4.8e-05 22.8 1.3 0.28 10.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 ETS59587.1 - 9.8e-05 22.5 0.0 0.49 10.6 0.0 3.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 ETS59587.1 - 0.00012 21.8 0.4 0.057 13.1 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETS59587.1 - 0.00014 22.3 0.0 0.072 13.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 ETS59587.1 - 0.00023 21.1 0.6 0.088 12.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain ABC_tran_2 PF12848.2 ETS59587.1 - 0.00024 20.8 5.7 0.00024 20.8 3.9 2.3 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 ETS59587.1 - 0.00078 19.3 0.1 0.19 11.5 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.1 ETS59587.1 - 0.0014 17.7 4.3 0.65 8.9 0.0 3.9 5 0 0 5 5 4 2 AAA ATPase domain Arch_ATPase PF01637.13 ETS59587.1 - 0.0015 18.3 0.5 0.36 10.5 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 ETS59587.1 - 0.0017 18.2 0.0 1.4 8.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 ETS59587.1 - 0.002 18.0 0.1 0.02 14.8 0.0 2.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 ETS59587.1 - 0.0037 17.0 1.6 4.9 6.8 0.1 3.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS59587.1 - 0.0043 17.2 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.17 ETS59587.1 - 0.0089 14.9 0.1 2.7 6.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ATP-grasp_3 PF02655.9 ETS59587.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain AAA_33 PF13671.1 ETS59587.1 - 0.014 15.2 4.6 0.87 9.4 0.0 3.4 3 1 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 ETS59587.1 - 0.016 13.8 6.6 0.067 11.7 0.1 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SRP54 PF00448.17 ETS59587.1 - 0.016 14.6 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 ETS59587.1 - 0.02 14.3 1.9 4.6 6.6 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein zf-met2 PF12907.2 ETS59587.1 - 0.022 14.7 0.7 0.043 13.7 0.5 1.4 1 0 0 1 1 1 0 Zinc-binding NTPase_1 PF03266.10 ETS59587.1 - 0.025 14.2 2.6 1.2 8.7 0.1 2.8 3 0 0 3 3 2 0 NTPase ArgK PF03308.11 ETS59587.1 - 0.042 12.6 8.2 3.1 6.5 0.1 3.9 4 0 0 4 4 4 0 ArgK protein AAA_10 PF12846.2 ETS59587.1 - 0.045 13.1 2.8 1.5 8.1 0.1 3.3 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 ETS59587.1 - 0.049 13.1 4.9 0.27 10.7 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 ETS59587.1 - 0.062 12.7 1.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 ETS59587.1 - 0.12 11.8 2.2 1.6 8.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 ETS59587.1 - 0.12 11.9 1.8 2.4 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS59587.1 - 0.21 11.9 8.5 0.2 11.9 0.9 3.2 3 1 0 3 3 2 0 AAA domain T2SE PF00437.15 ETS59587.1 - 2 7.2 7.0 0.33 9.8 0.0 2.7 4 0 0 4 4 2 0 Type II/IV secretion system protein Hid1 PF12722.2 ETS59587.1 - 7.4 4.1 6.6 13 3.3 4.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein F-box-like PF12937.2 ETS59588.1 - 4.9e-10 38.9 0.1 1.4e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS59588.1 - 3.1e-07 29.8 0.0 8.4e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 ETS59588.1 - 1.1e-05 25.0 0.4 0.0013 18.2 0.2 2.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETS59588.1 - 0.00011 21.8 2.4 0.047 13.6 0.5 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS59588.1 - 0.00074 19.0 1.5 0.013 15.0 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS59588.1 - 0.00081 19.1 0.4 0.00081 19.1 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS59588.1 - 0.051 13.5 3.1 0.099 12.5 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETS59588.1 - 0.1 12.8 0.0 0.42 10.9 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS59588.1 - 0.14 12.9 0.4 0.14 12.9 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS59588.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ADH_N PF08240.7 ETS59589.1 - 2.3e-26 91.6 2.5 2.3e-26 91.6 1.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS59589.1 - 6.7e-23 80.6 0.1 1.1e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS59589.1 - 0.038 14.8 0.0 0.091 13.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 ETS59589.1 - 0.045 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_permease_2 PF13520.1 ETS59590.1 - 2.9e-66 223.7 53.8 3.7e-66 223.4 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS59590.1 - 3.2e-08 32.3 49.6 1.2e-07 30.4 34.4 1.7 1 1 0 1 1 1 1 Amino acid permease DUF3377 PF11857.3 ETS59590.1 - 0.3 10.7 1.3 0.97 9.1 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Methyltransf_26 PF13659.1 ETS59591.1 - 4.2e-09 36.4 0.0 1e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETS59591.1 - 2.5e-08 33.7 0.0 0.00022 20.8 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 ETS59591.1 - 0.11 11.5 0.0 0.62 9.0 0.0 1.8 2 0 0 2 2 2 0 N-6 DNA Methylase Acetyltransf_1 PF00583.19 ETS59592.1 - 3.2e-05 23.8 0.0 7.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS59592.1 - 0.0085 16.2 0.1 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS59592.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 ETS59593.1 - 1e-20 73.6 2.5 1.9e-20 72.7 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS59593.1 - 0.0042 16.9 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.4 ETS59594.1 - 3.8e-19 68.9 0.0 1.7e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.7 ETS59594.1 - 0.011 15.1 0.0 0.031 13.6 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region S_tail_recep_bd PF14928.1 ETS59598.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain His_Phos_1 PF00300.17 ETS59600.1 - 2.2e-28 99.3 0.3 5.1e-28 98.1 0.1 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Peptidase_M50B PF13398.1 ETS59601.1 - 1.3e-59 200.9 15.3 1.7e-59 200.5 10.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Phage_holin_5 PF06946.6 ETS59602.1 - 0.046 13.8 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Phage holin UPF0029 PF01205.14 ETS59603.1 - 1.1e-27 95.8 0.0 2.5e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 ETS59603.1 - 1.5e-06 28.1 0.0 4.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 RWD domain Inhibitor_I9 PF05922.11 ETS59604.1 - 7.9e-09 35.9 0.1 2e-08 34.6 0.1 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 Thioredoxin PF00085.15 ETS59605.1 - 0.042 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin PRCC PF10253.4 ETS59605.1 - 0.21 12.2 2.1 0.28 11.8 1.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Rhomboid PF01694.17 ETS59606.1 - 5.3e-22 78.4 3.7 5.3e-22 78.4 2.6 1.8 2 0 0 2 2 2 1 Rhomboid family Pyridoxal_deC PF00282.14 ETS59607.1 - 5e-64 216.0 0.0 8.4e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF155 PF02582.9 ETS59607.1 - 1.5e-51 174.7 0.1 2.5e-51 174.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Beta_elim_lyase PF01212.16 ETS59607.1 - 4.4e-05 22.7 0.0 0.00013 21.2 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 ETS59607.1 - 0.0012 17.6 0.0 0.0047 15.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Methyltransf_31 PF13847.1 ETS59608.1 - 8.3e-18 64.4 0.0 1.6e-17 63.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS59608.1 - 2e-17 63.4 0.0 2.1e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS59608.1 - 1.4e-15 57.5 0.0 1.3e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS59608.1 - 3.1e-13 49.7 0.0 4.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS59608.1 - 5.5e-13 49.4 0.0 2.5e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS59608.1 - 8.8e-13 47.9 0.0 2e-12 46.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS59608.1 - 7.2e-11 41.7 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS59608.1 - 3.5e-10 40.1 0.0 6.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS59608.1 - 3.5e-08 33.2 0.0 4.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 ETS59608.1 - 4e-07 30.0 0.1 9.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS59608.1 - 1.2e-05 24.5 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 ETS59608.1 - 1.9e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS59608.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 ETS59608.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 ETS59608.1 - 0.00032 19.9 0.0 0.00045 19.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.5 ETS59608.1 - 0.00061 19.3 0.0 0.00081 18.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.8 ETS59608.1 - 0.008 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 RrnaAD PF00398.15 ETS59608.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 ETS59608.1 - 0.039 12.8 0.1 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 Fibrillarin N6_Mtase PF02384.11 ETS59608.1 - 0.088 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase MetW PF07021.7 ETS59608.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_3 PF01596.12 ETS59608.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DEAD PF00270.24 ETS59609.1 - 2.6e-22 79.1 0.0 4.5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 ETS59609.1 - 1.1e-12 48.3 1.3 5.1e-12 46.1 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 ETS59609.1 - 8e-12 44.8 0.0 2.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 ETS59609.1 - 3.2e-06 27.1 0.0 6.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like G10 PF01125.12 ETS59610.1 - 1.1e-30 106.1 0.3 1.3e-30 105.8 0.2 1.1 1 0 0 1 1 1 1 G10 protein Pkinase PF00069.20 ETS59611.1 - 1e-66 224.7 0.1 7.8e-58 195.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS59611.1 - 5.4e-31 107.6 0.0 5.6e-26 91.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS59611.1 - 0.00011 21.2 1.0 1.3 7.9 0.0 3.3 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 ETS59611.1 - 0.031 14.0 6.6 0.7 9.5 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 ETS59611.1 - 0.034 13.5 0.9 1.2 8.4 0.2 2.2 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 ETS59611.1 - 0.082 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase G_glu_transpept PF01019.16 ETS59613.1 - 7.9e-135 450.2 2.2 3.5e-133 444.7 1.6 2.0 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase GST_N_3 PF13417.1 ETS59615.1 - 5.3e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS59615.1 - 0.0044 16.9 0.0 0.017 15.0 0.0 1.8 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS59615.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS59615.1 - 0.048 13.5 0.0 0.086 12.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS59615.1 - 0.063 13.7 0.3 0.62 10.5 0.2 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Uricase PF01014.13 ETS59616.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Uricase DUF4193 PF13834.1 ETS59616.1 - 0.26 11.4 4.4 0.21 11.7 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) PBP1_TM PF14812.1 ETS59616.1 - 8.7 6.7 9.2 58 4.0 4.2 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lipase_3 PF01764.20 ETS59617.1 - 6e-17 61.5 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 ETS59617.1 - 0.011 15.5 0.2 0.04 13.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family MR_MLE_C PF13378.1 ETS59618.1 - 6.3e-14 51.8 0.1 1.6e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 ETS59618.1 - 3.7e-12 46.6 0.1 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 ETS59618.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 ETS59618.1 - 0.0067 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Abhydrolase_3 PF07859.8 ETS59619.1 - 1.8e-11 44.0 0.1 8.7e-11 41.7 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS59619.1 - 6.8e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS59619.1 - 8.2e-10 38.9 3.3 1.1e-09 38.4 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS59619.1 - 1.2e-05 24.6 0.1 0.00028 20.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 ETS59619.1 - 0.04 13.1 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase COesterase PF00135.23 ETS59619.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family LysM PF01476.15 ETS59620.1 - 2.7e-15 55.9 0.2 1.7e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 LysM domain SR-25 PF10500.4 ETS59620.1 - 2.9 7.3 25.2 0.24 10.8 12.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4551 PF15087.1 ETS59620.1 - 6.7 4.9 10.6 8.8 4.5 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RF-1 PF00472.15 ETS59621.1 - 6.1e-37 125.9 2.2 1.3e-36 124.8 1.5 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 ETS59621.1 - 2.3e-32 111.1 0.3 5.1e-32 110.0 0.2 1.5 1 0 0 1 1 1 1 PCRF domain HLH PF00010.21 ETS59622.1 - 2.4e-08 33.5 1.5 7.3e-08 31.9 1.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 ETS59622.1 - 1.3 9.0 8.7 0.14 12.1 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) DUF4098 PF13345.1 ETS59624.1 - 0.0088 15.9 0.6 6.5 6.7 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4098) Siva PF05458.7 ETS59625.1 - 0.26 10.8 3.9 0.48 9.9 2.7 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ECH PF00378.15 ETS59628.1 - 5.5e-41 140.2 0.9 1.3e-39 135.7 0.6 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PS_Dcarbxylase PF02666.10 ETS59629.1 - 2.1e-76 255.7 0.0 4.8e-58 195.7 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase Pmp3 PF01679.12 ETS59629.1 - 2.4e-19 68.7 8.7 4.1e-19 68.0 6.0 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Nnf1 PF03980.9 ETS59630.1 - 1.2e-10 41.3 8.2 1.2e-10 41.3 5.7 2.1 1 1 0 1 1 1 1 Nnf1 DUF2968 PF11180.3 ETS59630.1 - 0.0052 16.1 12.7 0.0052 16.1 8.8 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) DUF342 PF03961.8 ETS59630.1 - 0.011 14.2 1.5 0.017 13.5 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Dynein_heavy PF03028.10 ETS59630.1 - 0.036 12.1 1.7 0.045 11.7 1.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor V_ATPase_I PF01496.14 ETS59630.1 - 0.055 11.3 3.5 0.078 10.8 2.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 ETS59630.1 - 0.057 13.7 9.9 1.4 9.2 0.9 3.5 3 0 0 3 3 3 0 Snapin/Pallidin Filament PF00038.16 ETS59630.1 - 0.098 12.1 16.9 0.32 10.4 11.7 2.1 1 1 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.7 ETS59630.1 - 0.18 11.6 7.3 0.27 11.0 4.0 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 ETS59630.1 - 0.5 8.9 12.0 0.68 8.5 4.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 ETS59630.1 - 0.82 9.4 9.7 0.25 11.1 3.5 2.5 1 1 3 4 4 4 0 Laminin Domain II Fib_alpha PF08702.5 ETS59630.1 - 0.83 9.7 7.7 0.17 11.9 1.9 2.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 ETS59630.1 - 3.5 7.5 5.9 0.56 10.1 1.0 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.1 ETS59630.1 - 3.7 7.7 20.5 0.17 12.0 5.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.6 ETS59630.1 - 5.7 6.9 6.1 4.7 7.1 0.2 3.6 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Ank_5 PF13857.1 ETS59631.1 - 5.8e-28 96.2 1.6 2.8e-09 36.8 0.1 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS59631.1 - 1.3e-27 95.9 0.4 1.6e-19 70.0 0.0 3.0 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS59631.1 - 9.5e-26 88.2 0.7 6.9e-06 25.6 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 ETS59631.1 - 4e-25 87.7 1.2 8.6e-13 48.4 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) FYVE PF01363.16 ETS59631.1 - 6e-20 70.9 6.5 6e-20 70.9 4.5 2.8 2 1 1 3 3 3 1 FYVE zinc finger Ank_3 PF13606.1 ETS59631.1 - 9.6e-17 59.4 0.6 0.00028 20.8 0.0 5.3 5 0 0 5 5 4 4 Ankyrin repeat zf-RING_2 PF13639.1 ETS59631.1 - 2.9e-10 39.7 3.4 2.9e-10 39.7 2.4 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS59631.1 - 0.00055 19.8 4.4 0.00055 19.8 3.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS59631.1 - 0.0087 15.7 1.4 0.0087 15.7 1.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 ETS59631.1 - 0.016 15.3 3.5 0.019 15.0 1.1 2.1 2 0 0 2 2 1 0 RING-H2 zinc finger RINGv PF12906.2 ETS59631.1 - 0.044 13.8 2.8 0.16 12.0 1.9 2.0 1 0 0 1 1 1 0 RING-variant domain FYVE_2 PF02318.11 ETS59631.1 - 0.045 13.6 1.1 0.15 11.9 0.7 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger FANCL_C PF11793.3 ETS59631.1 - 0.36 10.8 5.5 0.19 11.7 1.5 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain Pex24p PF06398.6 ETS59631.1 - 0.39 9.4 0.1 0.7 8.6 0.1 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PepSY_TM_2 PF13703.1 ETS59632.1 - 0.021 15.0 0.2 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Hist_deacetyl PF00850.14 ETS59633.1 - 1.3e-94 317.0 0.0 1.9e-94 316.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 ETS59633.1 - 7.3e-20 71.1 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain Cutinase PF01083.17 ETS59633.1 - 0.028 14.1 0.2 0.095 12.4 0.0 1.8 2 0 0 2 2 2 0 Cutinase UPF0565 PF10561.4 ETS59633.1 - 0.036 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 FIST PF08495.5 ETS59634.1 - 5.6e-05 22.3 2.1 0.00029 20.0 0.0 2.8 3 1 1 4 4 4 1 FIST N domain Arf PF00025.16 ETS59635.1 - 2.8e-14 52.7 0.0 1e-10 41.1 0.0 3.0 3 0 0 3 3 3 2 ADP-ribosylation factor family G-alpha PF00503.15 ETS59635.1 - 0.00043 19.0 0.0 0.0029 16.3 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit Ras PF00071.17 ETS59635.1 - 0.00077 18.8 0.0 3.4 7.0 0.0 3.0 3 0 0 3 3 3 2 Ras family Miro PF08477.8 ETS59635.1 - 0.00078 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Apc13p PF05839.6 ETS59635.1 - 0.0041 17.0 0.0 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 Apc13p protein MMR_HSR1 PF01926.18 ETS59635.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS59635.1 - 0.072 13.0 0.2 0.36 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 ETS59635.1 - 0.085 12.5 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 ETS59635.1 - 0.086 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 ETS59635.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 3HCDH_N PF02737.13 ETS59636.1 - 6.8e-45 152.9 4.9 5.7e-44 149.9 3.4 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETS59636.1 - 1.8e-33 114.8 0.0 3.3e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_3 PF13738.1 ETS59636.1 - 0.047 13.7 0.5 0.093 12.7 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS59636.1 - 0.11 11.3 0.2 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cloacin PF03515.9 ETS59636.1 - 0.12 11.5 0.7 0.19 10.9 0.5 1.3 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain RGS PF00615.14 ETS59637.1 - 1.9e-37 127.9 0.0 8.2e-37 125.9 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 ETS59637.1 - 8.7e-12 44.6 0.0 4.8e-05 23.0 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 ETS59637.1 - 0.019 14.7 0.2 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix Lipase_3 PF01764.20 ETS59640.1 - 1.3e-27 96.1 0.0 1.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 ETS59640.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 ETS59640.1 - 0.056 13.2 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS59640.1 - 0.14 11.9 2.9 0.12 12.2 0.7 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_6 PF03737.10 ETS59641.1 - 1e-24 87.1 0.4 5.5e-23 81.5 0.2 2.5 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase SAP PF02037.22 ETS59641.1 - 4.3e-09 35.6 0.4 7.3e-09 34.9 0.3 1.4 1 0 0 1 1 1 1 SAP domain DsrH PF04077.7 ETS59641.1 - 0.04 13.5 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 DsrH like protein DUF1539 PF07560.6 ETS59641.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) UPF0172 PF03665.8 ETS59642.1 - 1e-47 162.1 0.1 1.2e-47 161.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 ETS59642.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.6 1 1 1 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_11 PF13414.1 ETS59643.1 - 4e-24 84.0 23.0 9.7e-11 41.1 0.6 7.3 5 3 2 7 7 7 5 TPR repeat TPR_1 PF00515.23 ETS59643.1 - 8e-18 63.2 11.2 0.012 15.1 0.0 8.0 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETS59643.1 - 1.1e-17 62.4 24.0 0.055 13.4 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETS59643.1 - 2.2e-14 53.6 41.0 0.00011 22.7 0.0 7.9 5 2 4 9 9 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETS59643.1 - 7.9e-13 47.8 30.3 0.034 14.7 0.2 9.5 5 1 4 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETS59643.1 - 8e-12 44.0 4.2 0.086 12.6 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS59643.1 - 4.3e-10 38.9 1.9 0.16 12.2 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS59643.1 - 5.2e-08 33.1 12.3 1.1 9.6 1.7 6.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS59643.1 - 8.5e-08 32.0 22.6 0.00031 20.6 1.7 6.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETS59643.1 - 0.089 13.2 15.0 27 5.5 0.1 8.2 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETS59643.1 - 0.59 10.0 24.8 0.016 15.0 2.2 5.7 5 1 2 7 7 7 0 Tetratricopeptide repeat Macoilin PF09726.4 ETS59643.1 - 2.1 6.5 17.7 4.7 5.3 12.3 1.6 1 0 0 1 1 1 0 Transmembrane protein ADK PF00406.17 ETS59644.1 - 3.3e-57 192.5 0.0 4.3e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 ETS59644.1 - 6.6e-14 51.2 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 ETS59644.1 - 8.9e-05 22.3 0.0 0.0002 21.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS59644.1 - 0.00077 18.6 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 ETS59644.1 - 0.0086 16.2 0.1 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETS59644.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS59644.1 - 0.014 16.1 0.0 0.03 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS59644.1 - 0.054 13.6 0.1 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fib_alpha PF08702.5 ETS59644.1 - 0.062 13.4 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_5 PF07728.9 ETS59644.1 - 0.062 13.0 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 ETS59644.1 - 0.083 12.3 0.1 14 5.1 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase MT0933_antitox PF14013.1 ETS59644.1 - 0.084 12.9 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 MT0933-like antitoxin protein Thymidylate_kin PF02223.12 ETS59644.1 - 0.089 12.1 0.1 2.5 7.4 0.0 2.7 2 1 0 3 3 3 0 Thymidylate kinase He_PIG PF05345.7 ETS59645.1 - 0.00082 19.3 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Putative Ig domain Arrestin_C PF02752.17 ETS59646.1 - 6.6e-17 61.8 0.0 1.5e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS59646.1 - 0.016 15.0 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Galactosyl_T PF01762.16 ETS59647.1 - 2.5e-10 40.2 1.5 9.4e-05 22.0 0.0 3.8 3 1 1 4 4 4 3 Galactosyltransferase SNF2_N PF00176.18 ETS59648.1 - 3.2e-65 219.8 0.0 5.5e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 ETS59648.1 - 1.6e-52 178.1 0.4 3.5e-52 177.0 0.2 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 ETS59648.1 - 3.6e-12 45.9 0.0 1.6e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETS59648.1 - 1.6e-08 33.7 0.0 5.8e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 ETS59648.1 - 0.0001 22.4 0.2 0.0081 16.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 ETS59648.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit L31 PF09784.4 ETS59649.1 - 9.8e-43 144.4 0.4 1.1e-42 144.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 E1-E2_ATPase PF00122.15 ETS59650.1 - 6.5e-65 218.3 2.1 6.5e-65 218.3 1.5 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS59650.1 - 4.5e-44 150.1 4.0 5.2e-44 149.9 1.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS59650.1 - 1.2e-33 117.3 0.0 1.3e-32 114.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS59650.1 - 1.1e-23 82.4 0.0 2.4e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 ETS59650.1 - 2e-19 69.3 0.0 3.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS59650.1 - 2.5e-16 60.4 0.1 1.1e-15 58.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS59650.1 - 6.1e-09 35.8 1.0 9e-06 25.4 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS59650.1 - 0.013 15.7 0.1 0.082 13.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SAP25 PF15476.1 ETS59652.1 - 0.3 10.5 4.6 0.48 9.9 3.0 1.4 1 1 0 1 1 1 0 Histone deacetylase complex subunit SAP25 S10_plectin PF03501.10 ETS59653.1 - 4.4e-40 135.4 0.1 5.3e-40 135.1 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 ETS59653.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Ribosomal_S30 PF04758.9 ETS59655.1 - 2.1e-25 88.2 9.8 5.8e-23 80.4 4.6 2.1 2 0 0 2 2 2 2 Ribosomal protein S30 Snf7 PF03357.16 ETS59656.1 - 5.7e-20 71.3 13.2 8.8e-20 70.7 9.2 1.2 1 0 0 1 1 1 1 Snf7 HA2 PF04408.18 ETS59657.1 - 4.1e-16 58.8 0.1 1.5e-15 57.0 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETS59657.1 - 3e-13 49.6 0.0 6.4e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 ETS59657.1 - 7.2e-12 45.0 0.0 2e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS59657.1 - 3.5e-07 29.8 0.0 8.5e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS59657.1 - 3.8e-05 23.8 0.0 8.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 ETS59657.1 - 0.0017 17.2 0.0 0.005 15.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 ETS59657.1 - 0.0055 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 ETS59657.1 - 0.073 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_2 PF03668.10 ETS59657.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family ABC_tran PF00005.22 ETS59657.1 - 0.099 12.9 0.0 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.10 ETS59657.1 - 0.17 11.7 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Calpain_III PF01067.17 ETS59658.1 - 3.2e-23 82.0 0.0 9e-13 48.1 0.0 5.3 3 2 0 3 3 3 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 ETS59658.1 - 1.1e-12 47.6 0.0 1.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 ETS59658.1 - 1.6e-06 27.9 0.1 2.5e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 ETS59659.1 - 7.3e-52 176.0 0.0 1.2e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS59659.1 - 5.7e-24 84.5 0.0 1.7e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS59659.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RPA_interact_N PF14766.1 ETS59659.1 - 0.18 11.3 3.3 0.41 10.1 2.3 1.7 1 0 0 1 1 1 0 Replication protein A interacting N-terminal DUF2346 PF09803.4 ETS59661.1 - 2.3e-06 27.3 3.1 7.7e-06 25.6 2.1 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) LMWPc PF01451.16 ETS59662.1 - 8.7e-29 100.6 0.0 1e-28 100.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase adh_short_C2 PF13561.1 ETS59663.1 - 3.3e-09 36.8 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS59663.1 - 7e-09 35.8 3.3 1.7e-08 34.5 2.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 ETS59663.1 - 0.00055 19.6 0.8 0.00094 18.8 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 ETS59663.1 - 0.013 15.2 1.8 0.019 14.6 0.6 1.9 2 0 0 2 2 2 0 KR domain ApbA PF02558.11 ETS59663.1 - 0.065 12.6 0.2 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CTDII PF01556.13 ETS59665.1 - 1.7e-27 95.1 0.3 1e-21 76.5 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 ETS59665.1 - 7.6e-23 80.0 3.3 1.2e-22 79.3 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 ETS59665.1 - 8.8e-10 38.4 17.6 8.8e-10 38.4 12.2 2.2 3 0 0 3 3 3 1 DnaJ central domain ATP-synt_F PF01990.12 ETS59666.1 - 1.3e-29 102.3 0.2 1.5e-29 102.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit CorC_HlyC PF03471.12 ETS59666.1 - 0.14 11.9 0.1 1.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Transporter associated domain MFS_1 PF07690.11 ETS59667.1 - 3.7e-47 160.7 46.0 2.8e-46 157.8 32.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS59667.1 - 1.1e-16 60.2 15.7 1.1e-16 60.2 10.9 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 ETS59668.1 - 4.2e-66 223.3 0.0 5.2e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 ETS59669.1 - 3e-07 30.2 10.0 5.8e-07 29.3 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 ETS59669.1 - 0.036 13.7 1.4 0.076 12.7 1.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 ETS59669.1 - 0.12 11.8 0.7 0.27 10.7 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4613 PF15390.1 ETS59669.1 - 0.38 8.8 1.6 0.57 8.2 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) ALAD PF00490.16 ETS59671.1 - 6.7e-122 406.4 0.0 7.5e-122 406.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Amidohydro_2 PF04909.9 ETS59671.1 - 0.0052 16.3 0.1 0.0074 15.8 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Rab15_effector PF15208.1 ETS59671.1 - 0.059 12.8 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Rab15 effector RNA_pol_3_Rpc31 PF11705.3 ETS59672.1 - 2.7e-38 132.1 34.5 5.8e-37 127.8 23.9 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Glyco_transf_28 PF03033.15 ETS59673.1 - 3.7e-20 72.0 0.0 8e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 ETS59673.1 - 6.5e-14 51.2 0.0 4.7e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 GRAM domain PH PF00169.24 ETS59673.1 - 1.7e-10 41.0 0.1 4.9e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 ETS59673.1 - 1.5e-07 31.4 0.0 7.5e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 ETS59673.1 - 0.0029 16.2 0.0 0.0051 15.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 ETS59673.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 PH domain PH_11 PF15413.1 ETS59673.1 - 0.027 14.7 0.1 0.16 12.2 0.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain TPR_11 PF13414.1 ETS59674.1 - 4.5e-53 176.7 30.5 1.7e-15 56.4 0.0 6.4 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 ETS59674.1 - 4.7e-47 155.7 32.0 1.3e-08 34.0 0.4 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETS59674.1 - 3.4e-36 120.2 30.3 4.1e-06 26.3 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 ETS59674.1 - 1.5e-20 72.9 21.6 5.6e-12 45.4 0.3 7.0 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETS59674.1 - 2.8e-19 69.2 26.2 1.3e-07 32.0 0.1 7.2 5 2 2 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETS59674.1 - 1.3e-17 62.6 21.9 0.02 15.5 0.0 10.1 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETS59674.1 - 3.7e-16 59.2 16.2 9.3e-05 22.6 0.0 7.4 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS59674.1 - 4.3e-16 57.4 20.7 0.0036 16.9 0.1 9.4 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS59674.1 - 4.8e-09 35.3 25.4 0.033 13.9 0.1 9.6 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS59674.1 - 1.6e-08 34.0 14.0 0.67 10.2 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 ETS59674.1 - 7.3e-08 32.4 14.5 7e-06 26.0 0.9 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETS59674.1 - 8.4e-07 28.7 10.8 0.026 14.3 0.0 7.1 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS59674.1 - 1.8e-05 24.8 18.1 1.6 9.3 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETS59674.1 - 0.0017 18.2 14.6 0.084 12.8 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 ETS59674.1 - 0.0019 18.3 1.4 0.049 13.7 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Inhibitor_I9 PF05922.11 ETS59674.1 - 0.83 10.2 0.0 0.83 10.2 0.0 3.1 4 0 0 4 4 1 0 Peptidase inhibitor I9 PAS_4 PF08448.5 ETS59674.1 - 6 6.9 9.4 2.3 8.3 0.0 3.6 4 0 0 4 4 3 0 PAS fold Suf PF05843.9 ETS59675.1 - 2e-85 286.9 0.3 2.7e-80 270.1 0.0 4.4 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 ETS59675.1 - 0.01 16.3 28.9 0.46 11.2 0.0 8.7 8 1 1 9 9 9 0 Tetratricopeptide repeat HAT PF02184.11 ETS59675.1 - 0.033 13.9 3.2 3.7 7.3 0.0 4.3 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat zf-DHHC PF01529.15 ETS59676.1 - 3.4e-17 62.3 0.0 5.5e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase STAG PF08514.6 ETS59677.1 - 1.2e-26 92.7 2.1 4.3e-26 90.9 0.3 2.8 2 1 1 3 3 3 1 STAG domain HEAT PF02985.17 ETS59677.1 - 0.002 18.0 0.1 1.6 9.0 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat PAS PF00989.19 ETS59678.1 - 5.3e-11 42.3 0.0 6.8e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 ETS59678.1 - 2.6e-10 40.5 0.0 6.8e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 ETS59678.1 - 4.9e-09 36.1 0.0 8.1e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 ETS59678.1 - 4.7e-08 33.0 0.0 1.3e-05 25.1 0.0 2.6 1 1 1 2 2 2 2 PAS fold PAS_11 PF14598.1 ETS59678.1 - 0.0022 17.9 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 ETS59678.1 - 0.02 14.7 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 PAS domain TauD PF02668.11 ETS59679.1 - 1.9e-38 132.5 0.0 3.2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 ETS59679.1 - 3.3e-05 24.2 0.0 0.00015 22.0 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 ETS59679.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 CsiD Proteasome PF00227.21 ETS59682.1 - 3.9e-57 192.6 0.3 7e-57 191.7 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit Ras PF00071.17 ETS59682.1 - 8.6e-45 152.0 0.0 1.3e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS59682.1 - 1.5e-17 64.1 0.0 3.6e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Proteasome_A_N PF10584.4 ETS59682.1 - 1e-14 53.4 0.3 2.1e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Arf PF00025.16 ETS59682.1 - 3.6e-06 26.3 0.0 6.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS59682.1 - 0.00032 20.6 0.1 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS59682.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETS59682.1 - 0.13 11.4 0.1 0.36 9.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 tRNA-synt_1g PF09334.6 ETS59684.1 - 7.6e-108 360.6 0.3 4.2e-95 318.6 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETS59684.1 - 4.8e-15 54.5 0.1 6.3e-08 31.0 0.0 2.4 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 ETS59684.1 - 4.5e-07 29.2 0.1 0.018 14.1 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 ETS59684.1 - 5.4e-05 22.9 0.4 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Peptidase_C28 PF05408.6 ETS59684.1 - 0.043 13.2 0.2 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase tRNA-synt_1f PF01921.13 ETS59684.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Asp PF00026.18 ETS59685.1 - 4e-71 239.8 7.8 6.4e-71 239.1 5.4 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS59685.1 - 2.4e-08 34.0 1.9 2.4e-08 34.0 1.3 2.9 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal PPR_2 PF13041.1 ETS59686.1 - 2.6e-06 27.2 0.0 1.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 ETS59686.1 - 0.0012 18.9 0.1 0.0012 18.9 0.1 5.4 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 ETS59686.1 - 0.0051 16.7 0.0 0.032 14.2 0.0 2.6 1 0 0 1 1 1 1 PPR repeat UPF0261 PF06792.6 ETS59687.1 - 7.5e-118 393.5 0.0 1e-117 393.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 ETS59688.1 - 1.8e-129 430.5 0.2 2e-129 430.3 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 ETS59688.1 - 0.0021 17.2 0.2 0.0034 16.5 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase SPOR PF05036.8 ETS59688.1 - 0.061 13.4 0.0 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain zf-C2H2 PF00096.21 ETS59689.1 - 4e-07 30.0 10.3 0.0012 19.1 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS59689.1 - 2.3e-05 24.4 3.8 2.3e-05 24.4 2.7 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS59689.1 - 3.5e-05 23.8 9.4 0.023 15.0 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Sugar_tr PF00083.19 ETS59691.1 - 3.1e-114 382.0 22.0 3.8e-114 381.7 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter zf-Tim10_DDP PF02953.10 ETS59691.1 - 1.2e-19 69.3 0.6 2.1e-19 68.5 0.4 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MFS_1 PF07690.11 ETS59691.1 - 9.6e-16 57.4 42.2 1.1e-12 47.3 14.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 ETS59692.1 - 9e-13 48.6 2.7 9e-13 48.6 1.9 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS59692.1 - 4.7e-12 45.8 0.0 9.8e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 ETS59692.1 - 2.8e-09 36.0 0.0 4.6e-09 35.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.15 ETS59692.1 - 0.00013 21.6 0.1 0.015 14.8 0.0 2.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 ETS59692.1 - 0.0048 16.3 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) MIF4G PF02854.14 ETS59693.1 - 3.3e-29 101.7 0.5 4.6e-28 98.0 0.0 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 ETS59693.1 - 1.2e-26 92.5 0.1 2.4e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 MA3 domain COX6B PF02297.12 ETS59693.1 - 6.8e-24 83.6 0.7 1.6e-23 82.5 0.5 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sigma70_ner PF04546.8 ETS59693.1 - 1 8.9 7.2 6.9 6.2 0.1 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region CTP_transf_2 PF01467.21 ETS59694.1 - 1.5e-29 103.1 0.0 2.2e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Pox_MCEL PF03291.11 ETS59695.1 - 1.3e-73 247.8 0.0 1.7e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 ETS59695.1 - 2.8e-08 33.6 0.0 6.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS59695.1 - 1e-07 32.3 0.0 2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS59695.1 - 3.1e-07 30.0 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS59695.1 - 7.3e-06 26.5 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS59695.1 - 7.6e-06 26.3 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS59695.1 - 0.00098 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 ETS59695.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family tRNA-synt_1 PF00133.17 ETS59696.1 - 3.2e-156 520.8 0.0 4.5e-156 520.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETS59696.1 - 1.1e-27 96.7 0.0 1.9e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETS59696.1 - 1.2e-22 80.1 0.0 8.4e-13 47.7 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 ETS59696.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 ETS59696.1 - 0.18 10.9 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Zn_clus PF00172.13 ETS59698.1 - 5.7e-06 26.1 7.5 9.9e-06 25.3 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2306 PF10067.4 ETS59699.1 - 0.001 19.1 2.8 0.0013 18.8 1.1 1.7 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) AMP-binding PF00501.23 ETS59700.1 - 2.2e-216 718.1 1.2 1.3e-76 257.7 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 ETS59700.1 - 6.4e-147 488.2 0.1 2.1e-39 135.1 0.1 5.8 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.20 ETS59700.1 - 8.4e-37 125.2 4.1 7.6e-09 35.7 0.1 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS59700.1 - 4e-16 59.7 0.1 3.6e-07 31.0 0.0 4.5 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 ETS59700.1 - 8.4e-05 21.2 0.0 6.7 5.1 0.0 4.7 5 0 0 5 5 5 2 Alcohol acetyltransferase ECH PF00378.15 ETS59701.1 - 3.3e-58 196.6 0.0 4.4e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Acetyltransf_8 PF13523.1 ETS59702.1 - 2e-25 89.4 0.0 6.2e-25 87.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 ETS59703.1 - 1.1e-59 202.1 24.9 1e-31 110.4 7.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS59703.1 - 3.1e-50 170.0 0.2 3.5e-28 98.6 0.1 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS59703.1 - 7.8e-10 38.3 1.3 1.6e-05 24.2 0.0 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 ETS59703.1 - 2.6e-08 33.2 0.3 0.0044 16.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS59703.1 - 2.8e-06 27.4 5.9 0.021 14.8 0.2 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 ETS59703.1 - 2.9e-06 26.7 1.3 0.046 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 ETS59703.1 - 1e-05 24.5 0.1 0.04 12.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 ETS59703.1 - 1.5e-05 25.4 1.2 0.021 15.3 0.1 2.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETS59703.1 - 1.9e-05 24.5 0.2 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 ETS59703.1 - 2.2e-05 23.9 4.7 0.05 13.0 0.3 3.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 ETS59703.1 - 5.9e-05 23.2 0.7 0.1 12.8 0.1 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS59703.1 - 0.00013 21.5 0.1 0.19 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 ETS59703.1 - 0.00018 21.6 0.9 0.086 12.9 0.2 3.1 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 ETS59703.1 - 0.00087 18.1 2.6 0.076 11.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 ETS59703.1 - 0.00094 19.9 0.1 1 10.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 ETS59703.1 - 0.0015 18.1 6.0 0.13 11.8 0.5 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 ETS59703.1 - 0.0018 18.1 3.2 0.53 10.1 0.9 3.2 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS59703.1 - 0.0032 16.9 0.2 0.4 10.1 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 ETS59703.1 - 0.0037 16.3 1.9 1.4 7.9 0.1 2.8 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 ETS59703.1 - 0.0039 17.3 0.7 1.2 9.3 0.0 3.3 4 0 0 4 4 2 1 RNA helicase ATP_bind_1 PF03029.12 ETS59703.1 - 0.004 16.7 5.0 1.8 8.0 0.4 3.3 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein MobB PF03205.9 ETS59703.1 - 0.0041 16.8 4.4 0.52 10.0 0.0 3.0 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 ETS59703.1 - 0.0042 16.9 5.3 0.14 11.9 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 ETS59703.1 - 0.0043 16.7 0.7 0.095 12.3 0.0 3.0 3 1 0 3 3 3 1 Archaeal ATPase AAA_21 PF13304.1 ETS59703.1 - 0.0071 16.3 0.1 15 5.4 0.0 4.0 3 1 0 4 4 4 0 AAA domain IstB_IS21 PF01695.12 ETS59703.1 - 0.0073 15.7 2.2 4.3 6.7 0.1 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.8 ETS59703.1 - 0.0074 15.2 0.6 2.1 7.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 ETS59703.1 - 0.033 12.8 2.8 1.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 ETS59703.1 - 0.034 13.7 1.1 3.1 7.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 ETS59703.1 - 0.043 13.7 0.8 0.41 10.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 ETS59703.1 - 0.056 13.0 2.1 6.4 6.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 ETS59703.1 - 0.12 12.6 0.9 8.4 6.7 0.1 2.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 ETS59703.1 - 0.14 11.5 1.0 14 5.0 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETS59703.1 - 0.17 11.6 9.3 0.22 11.3 0.2 2.9 4 0 0 4 4 2 0 Dynamin family AAA_23 PF13476.1 ETS59703.1 - 0.33 11.2 2.9 7.1 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 ETS59703.1 - 0.9 9.4 6.6 2 8.3 0.3 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 ETS59703.1 - 1.4 8.3 5.5 7.1 6.0 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.14 ETS59703.1 - 1.5 8.1 6.8 7.8 5.8 0.2 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 ETS59703.1 - 5.8 6.6 6.8 2.3 7.9 0.1 3.1 3 0 0 3 3 3 0 NTPase MFS_1 PF07690.11 ETS59704.1 - 4.4e-20 71.7 38.0 5.1e-19 68.2 21.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 ETS59704.1 - 0.0021 18.0 0.7 0.023 14.6 0.3 2.8 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 Pyr_redox PF00070.22 ETS59705.1 - 2.9e-09 37.1 0.0 9.1e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS59705.1 - 1.1e-08 35.1 0.0 2e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS59705.1 - 0.11 11.4 0.1 0.73 8.6 0.0 2.1 2 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Bac_rhamnosid PF05592.6 ETS59706.1 - 1e-23 83.3 0.0 7.1e-17 60.7 0.0 3.1 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase UNC45-central PF11701.3 ETS59707.1 - 3.1e-08 33.4 0.1 1.1e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central RNA_pol_Rpb1_5 PF04998.12 ETS59708.1 - 9e-94 313.8 0.3 1.3e-93 313.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 ETS59708.1 - 5.6e-88 295.4 0.0 7.8e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 ETS59708.1 - 1.7e-66 223.2 0.0 3.2e-66 222.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 FAA_hydrolase PF01557.13 ETS59708.1 - 8.6e-51 172.4 0.0 1.8e-50 171.4 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RNA_pol_Rpb1_3 PF04983.13 ETS59708.1 - 7.6e-37 126.4 0.0 3.8e-36 124.2 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 ETS59708.1 - 6.7e-31 106.2 0.0 1.5e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 ETS59708.1 - 0.028 13.9 0.1 0.079 12.4 0.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain Baculo_ME53 PF06061.6 ETS59708.1 - 0.03 13.2 0.1 0.057 12.4 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 DUF2225 PF09986.4 ETS59708.1 - 0.074 12.4 0.4 0.14 11.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF1793 PF08760.6 ETS59709.1 - 2.2e-68 229.4 0.4 2.2e-68 229.4 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) URO-D PF01208.12 ETS59710.1 - 2.3e-133 444.3 0.0 2.7e-133 444.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) RTA1 PF04479.8 ETS59711.1 - 7.2e-35 120.5 7.1 1e-34 120.0 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF308 PF03729.8 ETS59711.1 - 0.0014 18.5 1.5 0.0014 18.5 1.1 3.5 3 1 0 3 3 3 1 Short repeat of unknown function (DUF308) Na_H_Exchanger PF00999.16 ETS59712.1 - 4.3e-18 65.0 43.2 2e-13 49.6 8.0 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Pkinase PF00069.20 ETS59713.1 - 3.9e-69 232.6 0.0 6e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_3 PF07859.8 ETS59713.1 - 1.1e-47 162.3 0.2 2.6e-47 161.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 ETS59713.1 - 3.8e-34 117.9 0.0 5.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2424 PF10340.4 ETS59713.1 - 2.1e-12 46.3 0.0 6e-12 44.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) YrbL-PhoP_reg PF10707.4 ETS59713.1 - 4.2e-07 29.5 0.0 7.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 ETS59713.1 - 0.0057 15.7 0.4 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family GlnD_UR_UTase PF08335.6 ETS59713.1 - 0.017 14.9 0.2 0.045 13.5 0.2 1.6 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase Kinase-like PF14531.1 ETS59713.1 - 0.052 12.5 0.0 0.63 8.9 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 ETS59713.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2422 PF10337.4 ETS59714.1 - 3.7e-112 375.4 1.4 3.7e-112 375.4 1.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 ETS59714.1 - 9e-23 81.0 0.1 3.4e-11 43.2 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 ETS59714.1 - 3.4e-08 33.4 20.3 3.4e-08 33.4 14.1 4.0 2 2 3 5 5 5 1 Fusaric acid resistance protein-like HMG_box PF00505.14 ETS59715.1 - 1.5e-15 57.1 2.2 3.1e-15 56.2 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS59715.1 - 1.3e-11 44.6 1.1 2.3e-11 43.8 0.8 1.4 1 0 0 1 1 1 1 HMG-box domain KfrA_N PF11740.3 ETS59715.1 - 0.039 14.3 0.4 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DinB_2 PF12867.2 ETS59716.1 - 0.005 17.1 0.0 0.008 16.5 0.0 1.4 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.7 ETS59716.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 DinB family DUF3931 PF13082.1 ETS59716.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) Translin PF01997.11 ETS59717.1 - 2.8e-53 180.5 0.1 3.4e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Translin family PilJ PF13675.1 ETS59717.1 - 0.12 12.6 1.1 2 8.7 0.1 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3671 PF12420.3 ETS59718.1 - 5.7 6.9 4.9 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function Vfa1 PF08432.5 ETS59720.1 - 2.2e-35 122.3 7.6 3.6e-35 121.6 5.2 1.3 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 FKBP_N PF01346.13 ETS59720.1 - 0.015 15.3 0.9 0.029 14.4 0.6 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Spore_coat_CotO PF14153.1 ETS59720.1 - 0.033 13.6 1.7 0.05 13.0 1.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF566 PF04484.7 ETS59720.1 - 1.2 8.6 6.4 1.5 8.2 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) UPF0278 PF08745.6 ETS59722.1 - 0.054 12.7 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 UPF0278 family PMI_typeI PF01238.16 ETS59724.1 - 1.4e-110 369.8 0.0 1.7e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 ETS59724.1 - 5.1e-06 25.8 0.0 0.0017 17.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain DUF2834 PF11196.3 ETS59725.1 - 2.6e-05 24.2 14.1 0.0063 16.6 1.1 4.4 4 0 0 4 4 4 4 Protein of unknown function (DUF2834) Strabismus PF06638.6 ETS59725.1 - 0.44 8.8 1.4 0.77 7.9 1.0 1.3 1 0 0 1 1 1 0 Strabismus protein CGI-121 PF08617.5 ETS59726.1 - 2e-41 141.3 0.0 3.2e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 Kinase binding protein CGI-121 NDUF_B7 PF05676.8 ETS59727.1 - 2.2e-17 62.2 0.1 3.2e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 ETS59727.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2638 PF10937.3 ETS59728.1 - 4.2e-07 30.9 1.2 5.6e-07 30.5 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF4211 PF13926.1 ETS59729.1 - 5.5e-10 38.8 0.1 1.1e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) vMSA PF00695.14 ETS59729.1 - 0.03 13.5 4.0 0.063 12.4 2.8 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus SNARE PF05739.14 ETS59730.1 - 8.8e-18 63.7 2.7 8.8e-18 63.7 1.9 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 ETS59730.1 - 3.2e-08 33.6 7.8 2e-07 31.0 0.1 2.8 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 ETS59730.1 - 0.016 14.7 2.1 0.025 14.1 0.2 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Aida_N PF08910.5 ETS59730.1 - 0.068 13.4 3.1 0.099 12.8 0.2 2.2 2 0 0 2 2 2 0 Aida N-terminus PMT PF02366.13 ETS59731.1 - 7.3e-74 248.2 12.9 7.3e-74 248.2 8.9 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 ETS59731.1 - 1.3e-44 151.9 0.5 1.1e-43 148.9 0.4 2.2 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.1 ETS59731.1 - 0.00019 21.3 13.3 0.00019 21.3 9.2 2.9 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Abhydro_lipase PF04083.11 ETS59732.1 - 1.7e-16 59.3 0.0 3.4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 ETS59732.1 - 0.0002 21.3 0.3 0.00047 20.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS59732.1 - 0.00096 18.9 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS59732.1 - 0.0012 18.4 1.3 0.0029 17.2 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Sec63 PF02889.11 ETS59733.1 - 1.5e-37 129.5 0.0 2.5e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 ETS59733.1 - 6e-16 57.9 1.1 1.5e-15 56.6 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain DDOST_48kD PF03345.9 ETS59733.1 - 0.032 12.7 0.1 6.5 5.1 0.0 2.3 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta PITH PF06201.8 ETS59734.1 - 1.3e-29 102.9 0.0 2.7e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 PITH domain MAM33 PF02330.11 ETS59735.1 - 6.3e-29 101.2 0.1 8.7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein RRM_1 PF00076.17 ETS59736.1 - 2.4e-16 59.1 0.0 1.6e-06 27.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS59736.1 - 3.6e-15 55.6 0.0 6.2e-08 32.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS59736.1 - 0.046 13.5 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAPS PF04499.10 ETS59736.1 - 9.9 4.6 13.1 2.2 6.8 3.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein tRNA-synt_2b PF00587.20 ETS59737.1 - 2e-27 95.8 0.0 2.9e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS59737.1 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Acyl-CoA_dh_1 PF00441.19 ETS59738.1 - 4.8e-46 156.5 3.9 4.8e-46 156.5 2.7 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS59738.1 - 8.7e-26 90.7 0.3 3.4e-25 88.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS59738.1 - 1.5e-23 83.5 1.3 1.5e-23 83.5 0.9 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS59738.1 - 8.2e-18 63.6 0.0 1.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Snf7 PF03357.16 ETS59738.1 - 0.0018 17.7 1.3 0.0037 16.6 0.9 1.4 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 ETS59738.1 - 0.067 12.9 0.2 4.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit DSPn PF14671.1 ETS59739.1 - 5.8e-35 120.3 0.0 5.8e-34 117.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half adh_short PF00106.20 ETS59739.1 - 1.7e-25 89.8 0.4 1.7e-25 89.8 0.3 2.2 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS59739.1 - 1e-22 81.1 0.0 1.7e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DSPc PF00782.15 ETS59739.1 - 6.6e-13 48.4 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain KR PF08659.5 ETS59739.1 - 1.6e-09 37.6 0.1 1.6e-09 37.6 0.1 2.3 3 0 0 3 3 3 1 KR domain Y_phosphatase PF00102.22 ETS59739.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETS59739.1 - 0.035 14.1 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF989 PF06181.6 ETS59739.1 - 0.13 11.3 0.4 0.22 10.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF989) UBA_e1_C PF09358.5 ETS59740.1 - 1.9e-43 147.6 0.1 3.5e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain ThiF PF00899.16 ETS59740.1 - 7.8e-43 145.5 0.1 2.9e-28 98.3 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 ETS59740.1 - 4.2e-37 125.5 0.1 9.2e-26 89.2 0.0 2.9 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 ETS59740.1 - 4.4e-26 89.9 1.1 1.6e-22 78.5 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Glyco_hydro_18 PF00704.23 ETS59743.1 - 2.4e-64 217.9 1.6 3e-64 217.6 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_66 PF13199.1 ETS59743.1 - 0.02 13.3 0.0 0.033 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 2-Hacid_dh_C PF02826.14 ETS59744.1 - 7.5e-27 93.6 0.2 1.2e-25 89.7 0.1 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 ETS59744.1 - 0.00025 20.1 0.3 0.00052 19.1 0.1 1.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain XdhC_C PF13478.1 ETS59744.1 - 0.003 17.8 0.1 0.011 16.0 0.0 1.9 1 1 1 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.1 ETS59744.1 - 0.011 16.0 0.2 0.037 14.2 0.2 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETS59744.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 ETS59744.1 - 0.066 13.6 0.1 1.9 8.9 0.1 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.17 ETS59745.1 - 4e-40 135.2 0.0 5.1e-21 74.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS59745.1 - 8.1e-34 115.4 0.0 1.3e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS59745.1 - 6.6e-17 61.0 0.0 2.8e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 ETS59745.1 - 0.19 10.1 37.4 0.25 9.7 25.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2217 PF10265.4 ETS59745.1 - 8.3 5.0 23.2 13 4.4 16.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) NUDIX PF00293.23 ETS59746.1 - 3.5e-17 62.2 0.0 8.2e-17 61.1 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.6 ETS59746.1 - 8.8e-11 42.0 0.4 3.9e-10 39.9 0.5 2.0 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain 7TM_GPCR_Str PF10326.4 ETS59746.1 - 0.15 11.1 0.0 2.1 7.3 0.0 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str EMG1 PF03587.9 ETS59747.1 - 6e-76 254.2 0.0 8.6e-76 253.7 0.0 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ank_2 PF12796.2 ETS59748.1 - 4.5e-22 78.1 0.3 1.7e-09 37.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS59748.1 - 3.8e-20 71.8 2.6 7.4e-11 42.2 0.1 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 ETS59748.1 - 1.8e-18 65.3 0.0 4.3e-08 32.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETS59748.1 - 1.2e-16 59.1 0.6 2.3e-05 24.1 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 ETS59748.1 - 6.8e-16 57.9 0.7 5.9e-08 32.7 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.8 ETS59748.1 - 2.1e-06 27.3 0.1 1.7e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain MoCF_biosynth PF00994.19 ETS59751.1 - 1.2e-58 196.6 0.7 3e-29 101.2 0.1 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 ETS59751.1 - 2.6e-30 104.9 0.3 3.9e-30 104.3 0.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 ETS59751.1 - 9.1e-10 38.3 0.9 4.9e-09 36.0 0.1 2.7 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) DUF2946 PF11162.3 ETS59751.1 - 0.15 12.3 8.4 0.57 10.3 5.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SH3_9 PF14604.1 ETS59752.1 - 8.4e-08 31.6 0.0 1.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS59752.1 - 7.1e-07 28.5 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS59752.1 - 0.00034 20.0 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ACBP PF00887.14 ETS59754.1 - 7e-28 96.1 0.0 1.2e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Peroxin-3 PF04882.7 ETS59755.1 - 8.1e-130 433.3 0.0 1.2e-129 432.8 0.0 1.2 1 0 0 1 1 1 1 Peroxin-3 PAM2 PF07145.10 ETS59755.1 - 0.0064 15.9 0.3 0.021 14.3 0.2 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region TIP49 PF06068.8 ETS59756.1 - 6.6e-189 627.6 0.8 1.7e-144 481.4 0.2 2.4 1 1 1 2 2 2 2 TIP49 C-terminus AAA PF00004.24 ETS59756.1 - 9.2e-10 38.8 1.0 2.3e-06 27.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS59756.1 - 1.3e-08 34.1 0.5 2.4e-05 23.5 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETS59756.1 - 2e-05 24.7 0.4 0.16 12.1 0.1 2.7 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS59756.1 - 5.8e-05 22.7 0.1 0.00046 19.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 ETS59756.1 - 0.00011 22.2 0.0 0.006 16.5 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 ETS59756.1 - 0.00027 20.6 0.1 0.095 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 ETS59756.1 - 0.00089 19.2 0.1 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETS59756.1 - 0.0027 17.1 0.5 0.0058 16.0 0.3 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 ETS59756.1 - 0.0048 16.3 0.1 2.3 7.6 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 ETS59756.1 - 0.0067 15.5 0.7 0.014 14.4 0.5 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 ETS59756.1 - 0.0084 15.2 0.1 0.49 9.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 ETS59756.1 - 0.013 14.8 0.1 0.04 13.3 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 ETS59756.1 - 0.037 13.7 0.2 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 NTPase Chlorosome_CsmC PF11098.3 ETS59756.1 - 0.048 13.3 0.1 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Chlorosome envelope protein C DUF2075 PF09848.4 ETS59756.1 - 0.05 12.5 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 ETS59756.1 - 0.082 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ALG3 PF05208.8 ETS59757.1 - 2.2e-110 369.3 16.5 2.2e-110 369.3 11.4 1.8 2 0 0 2 2 2 1 ALG3 protein Gaa1 PF04114.9 ETS59757.1 - 2.2e-46 158.6 14.5 9.1e-43 146.6 3.2 4.0 2 1 0 2 2 2 2 Gaa1-like, GPI transamidase component PBP1_TM PF14812.1 ETS59757.1 - 0.18 12.1 0.5 0.47 10.7 0.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ecm33 PF12454.3 ETS59757.1 - 1.7 8.5 6.0 0.68 9.8 0.5 2.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein EF-1_beta_acid PF10587.4 ETS59757.1 - 3.6 7.8 5.8 7.8 6.7 4.1 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region TAF4 PF05236.9 ETS59758.1 - 1.3e-29 103.2 1.0 1.4e-28 99.9 0.7 2.2 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 ETS59758.1 - 0.079 12.6 4.6 0.081 12.5 1.5 2.4 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit ZYG-11_interact PF05884.7 ETS59758.1 - 0.21 10.6 1.0 0.4 9.7 0.7 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3546 PF12066.3 ETS59759.1 - 8e-16 58.0 2.7 1.7e-15 56.9 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 ETS59759.1 - 1.3e-11 45.1 0.8 3.3e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Arsenite-resistance protein 2 MIF4G_like PF09088.6 ETS59760.1 - 4.2e-68 228.5 0.0 7.4e-68 227.7 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 ETS59760.1 - 4.2e-38 131.0 0.0 1.1e-37 129.6 0.0 1.6 1 1 0 1 1 1 1 MIF4G like Erythrovirus_X PF06795.6 ETS59760.1 - 0.053 13.5 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Erythrovirus X protein Spt4 PF06093.8 ETS59761.1 - 1.2e-32 111.6 0.0 1.4e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-DHHC PF01529.15 ETS59761.1 - 0.072 12.4 0.7 0.088 12.1 0.5 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Cyclin_N PF00134.18 ETS59762.1 - 4.2e-14 52.1 1.4 7.4e-14 51.4 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 ETS59762.1 - 0.0018 18.0 0.6 0.0041 16.8 0.4 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Abi PF02517.11 ETS59763.1 - 8.2e-12 45.1 5.0 8.2e-12 45.1 3.5 2.0 2 0 0 2 2 2 1 CAAX protease self-immunity PapJ PF14855.1 ETS59763.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone AAA PF00004.24 ETS59764.1 - 0.00078 19.6 0.0 0.0031 17.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS59764.1 - 0.036 13.8 0.7 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 ETS59764.1 - 0.053 13.6 0.3 0.42 10.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETS59764.1 - 0.067 13.1 0.0 0.067 13.1 0.0 3.8 3 2 1 4 4 4 0 AAA ATPase domain TIP49 PF06068.8 ETS59764.1 - 0.28 9.8 0.0 0.46 9.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RICTOR_N PF14664.1 ETS59766.1 - 3.5e-84 282.5 0.2 1e-83 280.9 0.2 1.8 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 ETS59766.1 - 2.7e-81 271.8 0.2 1.9e-79 265.8 0.0 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 ETS59766.1 - 1.2e-34 118.6 0.1 1.4e-33 115.2 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 ETS59766.1 - 1e-30 105.4 3.3 3.1e-29 100.7 0.2 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 ETS59766.1 - 8.3e-14 51.0 0.4 2.9e-13 49.3 0.3 2.0 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 ETS59766.1 - 0.0023 17.8 4.7 13 6.1 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Thioredoxin PF00085.15 ETS59767.1 - 2.2e-40 136.5 0.2 1.1e-21 76.4 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 ETS59767.1 - 5.7e-16 58.8 0.0 5.7e-08 32.7 0.0 3.7 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 ETS59767.1 - 3.9e-10 39.9 0.2 2.5e-05 24.4 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS59767.1 - 3.2e-06 27.1 0.1 0.0035 17.4 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 ETS59767.1 - 6.4e-06 26.1 0.1 0.00021 21.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.1 ETS59767.1 - 8.2e-06 25.9 2.6 0.11 12.4 0.1 3.4 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_3 PF13192.1 ETS59767.1 - 0.0002 21.0 0.0 0.093 12.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.5 ETS59767.1 - 0.0011 18.5 1.2 0.62 9.6 0.1 2.8 2 1 0 2 2 2 2 Redoxin AhpC-TSA PF00578.16 ETS59767.1 - 0.011 15.4 0.0 0.05 13.2 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Glutaredoxin PF00462.19 ETS59767.1 - 0.61 10.1 1.8 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Glutaredoxin His_biosynth PF00977.16 ETS59768.1 - 9.8e-35 119.8 0.0 1.6e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein GST_N PF02798.15 ETS59768.1 - 5.7e-10 39.2 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS59768.1 - 5.9e-06 26.4 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS59768.1 - 2.2e-05 24.3 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS59768.1 - 0.0079 16.6 0.0 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Actin PF00022.14 ETS59769.1 - 7.2e-159 528.4 0.0 8.3e-159 528.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 ETS59769.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SLT PF01464.15 ETS59770.1 - 4.9e-16 58.3 0.0 4.9e-16 58.3 0.0 2.8 2 2 1 3 3 3 1 Transglycosylase SLT domain Mem_trans PF03547.13 ETS59770.1 - 0.0045 15.3 4.4 0.0062 14.8 3.0 1.2 1 0 0 1 1 1 1 Membrane transport protein Macoilin PF09726.4 ETS59770.1 - 0.097 10.9 36.0 0.12 10.6 24.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 ETS59770.1 - 0.19 11.0 23.0 0.24 10.7 16.0 1.1 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 ETS59770.1 - 2.2 6.6 26.1 2.9 6.2 18.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Plasmodium_Vir PF05795.6 ETS59770.1 - 2.3 7.3 14.9 3.6 6.7 10.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOG2 PF10428.4 ETS59770.1 - 2.3 6.7 25.5 3.3 6.2 17.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1675 PF07897.6 ETS59770.1 - 2.3 7.9 28.7 3.6 7.3 19.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BUD22 PF09073.5 ETS59770.1 - 8.3 5.3 34.3 11 4.9 23.8 1.1 1 0 0 1 1 1 0 BUD22 Rad10 PF03834.9 ETS59771.1 - 2.5e-31 107.1 0.2 4.2e-31 106.4 0.1 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 ETS59771.1 - 1.8e-08 34.4 0.2 8.3e-08 32.2 0.0 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix domain UIM PF02809.15 ETS59771.1 - 0.064 12.8 0.8 0.27 10.9 0.5 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif Ribosomal_L2_C PF03947.13 ETS59772.1 - 6.3e-42 142.4 1.5 1.3e-41 141.4 1.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 ETS59772.1 - 1.8e-08 34.2 0.6 0.00011 22.0 0.4 2.6 2 0 0 2 2 2 2 Ribosomal Proteins L2, RNA binding domain GTP_EFTU PF00009.22 ETS59776.1 - 8.9e-33 113.3 1.3 2.4e-32 111.9 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 ETS59776.1 - 9.6e-17 60.8 0.3 7.1e-16 58.0 0.0 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 ETS59776.1 - 1.1e-14 54.2 4.1 3.3e-10 39.9 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS59776.1 - 8.7e-07 28.9 0.3 3.8e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETS59776.1 - 0.033 14.3 0.3 0.14 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Cgr1 PF03879.9 ETS59777.1 - 1e-28 99.6 23.9 1.2e-28 99.4 16.6 1.0 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 ETS59777.1 - 0.11 11.8 23.0 0.13 11.5 15.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dynamin_N PF00350.18 ETS59777.1 - 0.57 9.9 3.2 0.69 9.7 2.2 1.1 1 0 0 1 1 1 0 Dynamin family Atg14 PF10186.4 ETS59777.1 - 0.77 8.6 13.2 0.93 8.3 9.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PEARLI-4 PF05278.7 ETS59777.1 - 0.79 9.0 11.2 0.89 8.8 7.8 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) APG6 PF04111.7 ETS59777.1 - 1.4 7.9 9.0 1.4 7.8 6.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 ETS59777.1 - 3.5 5.7 13.2 3.7 5.6 9.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hom_end_hint PF05203.11 ETS59777.1 - 6.9 6.3 7.6 7.8 6.1 5.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint G-alpha PF00503.15 ETS59777.1 - 7.1 5.2 9.6 7.6 5.0 6.7 1.0 1 0 0 1 1 1 0 G-protein alpha subunit RR_TM4-6 PF06459.7 ETS59777.1 - 7.8 6.3 13.9 9 6.1 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP_sp32 PF07222.7 ETS59777.1 - 8.2 5.5 9.7 9 5.3 6.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2433 PF10360.4 ETS59778.1 - 8.2e-43 145.8 0.2 2.1e-42 144.5 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.17 ETS59778.1 - 6.8e-05 22.4 0.0 0.023 14.2 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 ETS59778.1 - 8.7e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_6 PF14259.1 ETS59778.1 - 0.0032 17.4 0.0 0.0092 15.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 ETS59778.1 - 0.072 12.9 0.1 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Myb_DNA-binding PF00249.26 ETS59779.1 - 0.016 15.2 3.2 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain PDCD9 PF07147.7 ETS59779.1 - 0.019 13.7 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) DEAD PF00270.24 ETS59780.1 - 4.5e-38 130.3 0.0 4.6e-37 127.1 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS59780.1 - 5.2e-18 64.6 0.0 1.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 ETS59780.1 - 3.4e-16 58.5 0.2 7e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 ETS59780.1 - 3e-05 23.9 0.0 6.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pol_alpha_B_N PF08418.5 ETS59780.1 - 6.2 6.2 13.2 17 4.8 9.1 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SDA1 PF05285.7 ETS59781.1 - 8.6e-89 298.0 41.2 8.6e-89 298.0 28.5 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 ETS59781.1 - 1.5e-19 70.0 0.1 3.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 NUC130/3NT domain VTC PF09359.5 ETS59782.1 - 7.7e-103 343.3 0.8 1.9e-102 342.0 0.0 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 ETS59782.1 - 4.2e-33 115.3 6.3 4.2e-33 115.3 4.3 3.4 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 ETS59782.1 - 5.7e-10 39.2 1.9 6.2e-10 39.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1154 PF06631.6 ETS59782.1 - 0.17 11.5 8.3 14 5.4 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1154) Fork_head PF00250.13 ETS59783.1 - 2.8e-22 78.5 0.1 1.1e-21 76.6 0.1 1.9 1 1 0 1 1 1 1 Fork head domain SH3_1 PF00018.23 ETS59785.1 - 1e-09 37.6 0.3 1.5e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS59785.1 - 0.0041 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 ETS59785.1 - 0.018 14.6 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Variant SH3 domain Nop PF01798.13 ETS59786.1 - 2.6e-58 195.5 0.1 2.6e-58 195.5 0.1 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 ETS59786.1 - 1.3e-25 88.9 0.2 4.1e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 ETS59786.1 - 2.6e-18 65.9 0.1 2.6e-18 65.9 0.1 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Proteasome PF00227.21 ETS59787.1 - 7.8e-48 162.2 1.8 2e-45 154.4 0.2 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 ETS59787.1 - 2.1e-15 55.7 0.4 3.6e-15 54.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cpn60_TCP1 PF00118.19 ETS59788.1 - 5.7e-137 457.2 10.7 6.7e-137 457.0 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DHBP_synthase PF00926.14 ETS59789.1 - 9.5e-77 256.6 0.0 1.1e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TPR_2 PF07719.12 ETS59790.1 - 1.3e-07 30.9 34.3 0.24 11.4 0.0 10.3 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETS59790.1 - 1.7e-06 28.4 6.2 6.9e-06 26.5 0.8 13.0 11 4 3 14 14 14 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETS59790.1 - 8.6e-06 25.1 16.0 0.045 13.3 0.6 6.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS59790.1 - 1.9e-05 24.2 3.2 0.00023 20.7 0.2 10.3 9 2 2 11 11 11 3 TPR repeat TPR_8 PF13181.1 ETS59790.1 - 2.9e-05 23.5 10.5 9.7 6.2 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS59790.1 - 0.054 13.8 59.4 0.36 11.1 0.2 12.4 12 2 1 13 13 13 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS59790.1 - 0.071 13.6 24.6 0.62 10.6 0.1 10.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS59790.1 - 0.25 12.0 0.0 0.1 13.2 0.5 13.4 14 3 2 16 16 16 0 Tetratricopeptide repeat SNO PF01174.14 ETS59791.1 - 8e-52 175.6 0.0 2.4e-42 144.6 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 ETS59791.1 - 2.6e-10 40.1 0.2 4.4e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 ETS59791.1 - 6.5e-05 22.4 0.1 0.0021 17.5 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 ETS59791.1 - 0.00023 20.9 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 ETS59791.1 - 0.0032 16.9 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family BPL_N PF09825.4 ETS59791.1 - 0.0077 15.0 0.0 0.16 10.7 0.0 2.0 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal DUF4066 PF13278.1 ETS59791.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase PIP5K PF01504.13 ETS59792.1 - 3.7e-43 147.4 0.0 1.5e-24 86.5 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase XPG_N PF00752.12 ETS59792.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain Ric8 PF10165.4 ETS59793.1 - 2e-99 333.4 0.0 6.2e-99 331.8 0.0 1.8 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn PIG-X PF08320.7 ETS59794.1 - 1.9e-20 73.0 0.1 1.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 PIG-X / PBN1 SNF2_N PF00176.18 ETS59796.1 - 4.7e-66 222.5 0.0 1.3e-65 221.1 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS59796.1 - 7.9e-14 51.2 0.0 2.1e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ADH_N PF08240.7 ETS59797.1 - 7.7e-27 93.2 2.4 7.7e-27 93.2 1.7 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS59797.1 - 3.7e-22 78.2 1.0 6.9e-22 77.3 0.7 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS59797.1 - 0.019 14.1 0.1 0.036 13.2 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 ETS59797.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 ETS59797.1 - 1.1 9.1 5.2 2.4 8.0 2.2 2.2 1 1 1 2 2 2 0 ThiF family Asp PF00026.18 ETS59798.1 - 6e-07 28.9 0.1 0.051 12.8 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS59798.1 - 0.0066 16.4 0.1 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS59798.1 - 0.016 15.6 1.7 2.8 8.4 0.2 3.0 2 1 0 2 2 2 0 Aspartyl protease Mur_ligase_M PF08245.7 ETS59799.1 - 0.0038 17.3 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Glyco_hydro_cc PF11790.3 ETS59800.1 - 2.4e-62 210.4 9.2 3.1e-62 210.1 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 ETS59800.1 - 0.00049 19.0 0.3 0.00049 19.0 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 Glyco_hydro_2_C PF02836.12 ETS59800.1 - 0.0027 16.6 0.1 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MTHFR PF02219.12 ETS59800.1 - 0.15 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Med13_C PF06333.7 ETS59802.1 - 0.00063 18.3 0.0 0.00063 18.3 0.0 3.9 4 2 1 5 5 5 1 Mediator complex subunit 13 C-terminal PPR_2 PF13041.1 ETS59803.1 - 4.3e-49 164.2 0.1 4.2e-09 36.2 0.0 11.9 9 2 4 13 13 13 11 PPR repeat family PPR_3 PF13812.1 ETS59803.1 - 7.9e-37 122.4 18.7 0.00062 19.8 0.0 15.7 16 0 0 16 16 16 7 Pentatricopeptide repeat domain PPR PF01535.15 ETS59803.1 - 3.2e-32 108.2 12.2 0.00021 21.0 0.0 14.6 18 0 0 18 18 16 5 PPR repeat PPR_1 PF12854.2 ETS59803.1 - 6.5e-21 73.5 9.3 0.0002 20.7 0.0 9.0 9 0 0 9 9 9 5 PPR repeat Methyltransf_11 PF08241.7 ETS59803.1 - 5.9e-13 49.1 0.0 2.9e-12 46.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS59803.1 - 2e-10 40.6 0.0 5.5e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS59803.1 - 4.2e-10 39.9 0.0 2.4e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS59803.1 - 5.6e-09 35.7 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS59803.1 - 4.4e-07 29.2 0.0 9.4e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETS59803.1 - 8.7e-05 22.8 0.1 0.0014 18.9 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain TPR_7 PF13176.1 ETS59803.1 - 0.0018 17.9 0.2 0.79 9.6 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Methyltransf_18 PF12847.2 ETS59803.1 - 0.0034 17.9 0.0 0.012 16.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Kinesin PF00225.18 ETS59804.1 - 5.1e-109 364.0 0.0 7.6e-109 363.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 ETS59804.1 - 3.2e-39 133.8 0.0 1e-38 132.1 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 ETS59804.1 - 2.1e-11 43.9 0.0 8e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 ETS59804.1 - 2.7e-09 36.9 0.7 6.8e-09 35.6 0.5 1.7 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 ETS59804.1 - 1.9e-06 27.9 0.0 3.9e-05 23.6 0.0 2.9 3 0 0 3 3 3 1 FHA domain PH_11 PF15413.1 ETS59804.1 - 5.3e-05 23.4 0.9 0.0001 22.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 ETS59804.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain SSF PF00474.12 ETS59805.1 - 2.4e-16 59.3 32.6 4.5e-16 58.4 22.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Fungal_trans PF04082.13 ETS59807.1 - 1.4e-25 89.7 0.0 2.8e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS59807.1 - 6.4e-08 32.3 11.1 1.1e-07 31.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS59808.1 - 1.2e-19 70.2 0.7 2e-19 69.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS59808.1 - 1.1e-08 34.8 9.7 1.9e-08 34.1 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF544 PF04424.8 ETS59809.1 - 1.5e-16 60.2 0.0 3.9e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Aminotran_4 PF01063.14 ETS59809.1 - 2.1e-11 43.7 0.0 1.3e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class IV NusA_N PF08529.6 ETS59809.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NusA N-terminal domain Pro_isomerase PF00160.16 ETS59810.1 - 5e-44 150.2 0.0 7.8e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 ETS59810.1 - 1.2e-06 27.9 5.1 0.0052 16.4 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETS59810.1 - 7.3e-06 25.5 7.1 0.002 17.8 0.9 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS59810.1 - 0.00026 20.8 4.4 0.12 12.3 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS59810.1 - 0.00073 19.0 4.5 0.0011 18.4 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS59810.1 - 0.066 13.0 0.8 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS59810.1 - 0.42 11.3 13.1 0.087 13.4 1.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tcf25 PF04910.9 ETS59811.1 - 1.2e-95 320.5 0.0 1.9e-95 319.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 YL1 PF05764.8 ETS59811.1 - 0.076 12.6 18.8 0.13 11.8 13.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein NST1 PF13945.1 ETS59811.1 - 0.23 11.5 14.3 0.43 10.6 9.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Spore_coat_CotO PF14153.1 ETS59811.1 - 0.56 9.6 13.1 1.3 8.4 9.1 1.5 1 0 0 1 1 1 0 Spore coat protein CotO TFIIF_alpha PF05793.7 ETS59811.1 - 0.58 8.4 28.1 0.96 7.7 19.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.4 ETS59811.1 - 9.1 4.4 15.4 13 3.9 10.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SCO1-SenC PF02630.9 ETS59812.1 - 1.1e-56 191.2 0.0 1.6e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC DUF4366 PF14283.1 ETS59812.1 - 0.0072 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) AhpC-TSA PF00578.16 ETS59812.1 - 0.12 12.1 0.0 0.42 10.2 0.0 2.0 1 1 0 1 1 1 0 AhpC/TSA family Eaf7 PF07904.8 ETS59813.1 - 1.3e-09 37.8 0.7 0.001 19.0 0.0 3.3 2 1 0 2 2 2 2 Chromatin modification-related protein EAF7 ACOX PF01756.14 ETS59814.1 - 1.9e-18 66.5 0.0 1.6e-16 60.2 0.0 3.0 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 ETS59814.1 - 3.4e-14 53.2 0.2 9.2e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 ETS59814.1 - 5.2e-10 38.6 0.2 1.1e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain COX7a PF02238.10 ETS59814.1 - 0.2 11.3 0.5 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Methyltransf_23 PF13489.1 ETS59815.1 - 1.8e-09 37.4 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS59815.1 - 1.8e-06 28.4 0.0 5.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS59815.1 - 0.00054 20.4 0.1 0.013 15.9 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS59815.1 - 0.001 19.5 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS59815.1 - 0.0022 18.3 0.0 0.0059 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS59815.1 - 0.0025 17.4 0.0 0.0058 16.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS59815.1 - 0.098 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_38 PF01074.17 ETS59816.1 - 9.9e-73 244.7 0.0 1.5e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 ETS59816.1 - 7.2e-46 156.9 0.0 1.1e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 ETS59816.1 - 9.1e-24 83.4 0.0 1.9e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 ETS59816.1 - 0.026 13.4 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 MFS_1 PF07690.11 ETS59817.1 - 7.7e-35 120.2 22.1 1.1e-34 119.7 15.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fumble PF03630.9 ETS59818.1 - 2.3e-112 375.2 0.0 9.6e-86 287.7 0.0 3.2 3 0 0 3 3 3 3 Fumble Abhydrolase_6 PF12697.2 ETS59818.1 - 2e-30 106.3 0.7 1.4e-29 103.5 0.5 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS59818.1 - 5.8e-17 62.0 0.0 3e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS59818.1 - 1e-13 51.2 0.0 4.1e-10 39.5 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Esterase PF00756.15 ETS59818.1 - 6.1e-06 25.8 0.0 1.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 ETS59818.1 - 5.5e-05 22.8 0.0 0.027 14.0 0.0 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold BAAT_C PF08840.6 ETS59818.1 - 0.00046 19.9 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.8 ETS59818.1 - 0.0017 17.9 0.1 0.0078 15.8 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Peptidase_S9 PF00326.16 ETS59818.1 - 0.006 15.8 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.9 ETS59818.1 - 0.012 14.1 0.0 0.02 13.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF2305 PF10230.4 ETS59818.1 - 0.041 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 ETS59818.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase HSCB_C PF07743.8 ETS59818.1 - 0.088 13.2 1.4 0.26 11.7 1.0 1.9 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF915 PF06028.6 ETS59818.1 - 0.24 10.4 0.1 1.1 8.3 0.0 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) V-SNARE PF05008.10 ETS59819.1 - 1.4e-21 76.4 10.6 3e-21 75.3 1.5 2.6 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 ETS59819.1 - 4.2e-17 61.9 6.0 4.2e-17 61.9 4.2 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus ApoLp-III PF07464.6 ETS59819.1 - 6.9e-05 22.9 5.7 0.0029 17.6 0.4 2.1 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.8 ETS59819.1 - 0.00017 21.8 9.1 0.065 13.6 0.4 3.1 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF883) Sec20 PF03908.8 ETS59819.1 - 0.00022 20.8 0.4 0.00022 20.8 0.3 1.9 2 0 0 2 2 2 1 Sec20 Prominin PF05478.6 ETS59819.1 - 0.0049 14.4 2.5 0.0065 14.0 1.7 1.3 1 1 0 1 1 1 1 Prominin Fusion_gly PF00523.13 ETS59819.1 - 0.0072 14.4 0.6 0.0072 14.4 0.4 1.6 2 0 0 2 2 2 1 Fusion glycoprotein F0 DUF3391 PF11871.3 ETS59819.1 - 0.01 16.0 8.8 0.34 11.1 1.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) PTS_IIA PF02255.11 ETS59819.1 - 0.03 14.1 1.7 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit HHV6-IE PF03753.8 ETS59819.1 - 0.043 11.3 0.0 0.063 10.7 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein YqjK PF13997.1 ETS59819.1 - 0.052 13.7 0.7 0.052 13.7 0.5 1.8 2 0 0 2 2 1 0 YqjK-like protein YukC PF10140.4 ETS59819.1 - 0.077 11.5 0.8 0.086 11.4 0.0 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC T2SF PF00482.18 ETS59819.1 - 0.1 12.5 1.8 0.53 10.2 1.0 2.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF607 PF04678.8 ETS59819.1 - 0.1 12.4 1.6 2.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF2130 PF09903.4 ETS59819.1 - 0.11 11.1 4.3 0.75 8.4 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF912 PF06024.7 ETS59819.1 - 0.13 12.3 0.2 0.13 12.3 0.1 2.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BLOC1_2 PF10046.4 ETS59819.1 - 0.13 12.4 5.5 0.79 9.9 0.3 2.5 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Trichoplein PF13868.1 ETS59819.1 - 0.28 9.5 13.5 0.058 11.7 2.8 2.0 2 0 0 2 2 2 0 Tumour suppressor, Mitostatin IFT57 PF10498.4 ETS59819.1 - 0.36 9.5 4.2 3.8 6.1 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4600 PF15372.1 ETS59819.1 - 0.38 10.9 7.2 0.74 10.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Fib_alpha PF08702.5 ETS59819.1 - 0.66 10.1 4.0 7.5 6.6 0.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CASP_C PF08172.7 ETS59819.1 - 0.66 8.9 8.6 2.1 7.3 0.5 2.3 1 1 1 2 2 2 0 CASP C terminal Apolipoprotein PF01442.13 ETS59819.1 - 0.74 9.2 10.6 3.2 7.2 0.5 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain OmpH PF03938.9 ETS59819.1 - 1 9.3 13.5 1.1 9.2 1.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Sigma_reg_N PF13800.1 ETS59819.1 - 1.3 9.1 5.9 0.67 10.0 2.4 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Sec8_exocyst PF04048.9 ETS59819.1 - 1.4 8.4 8.3 0.43 10.2 1.2 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Flagellin_N PF00669.15 ETS59819.1 - 7.1 6.4 14.7 2.4 7.9 6.7 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Myotub-related PF06602.9 ETS59820.1 - 2e-118 395.2 0.0 2.7e-117 391.5 0.0 2.1 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 ETS59820.1 - 0.014 14.7 0.1 0.035 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETS59820.1 - 0.018 15.3 0.0 0.064 13.5 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 ETS59820.1 - 0.046 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cation_efflux PF01545.16 ETS59821.1 - 1.3e-42 145.8 7.8 1.7e-42 145.4 5.4 1.2 1 0 0 1 1 1 1 Cation efflux family Rrn6 PF10214.4 ETS59822.1 - 1.3e-10 40.1 9.0 0.0055 14.8 0.2 4.3 3 1 1 4 4 4 4 RNA polymerase I-specific transcription-initiation factor Tfb2 PF03849.9 ETS59826.1 - 1.6e-144 481.0 0.0 2e-144 480.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 ETS59826.1 - 0.00023 20.9 0.1 0.0013 18.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain VIT1 PF01988.14 ETS59827.1 - 1.8e-78 262.8 2.8 2.5e-78 262.4 1.9 1.2 1 0 0 1 1 1 1 VIT family HemX PF04375.9 ETS59827.1 - 0.0086 14.7 2.7 0.02 13.4 1.9 1.6 1 0 0 1 1 1 1 HemX RecX PF02631.11 ETS59827.1 - 0.047 13.9 0.6 0.078 13.1 0.4 1.3 1 0 0 1 1 1 0 RecX family MRC1 PF09444.5 ETS59828.1 - 1.9e-30 106.1 23.9 1.9e-30 106.1 16.6 3.9 3 0 0 3 3 3 1 MRC1-like domain RAMP4 PF06624.7 ETS59829.1 - 7e-05 22.2 0.8 0.00014 21.3 0.2 1.8 1 1 1 2 2 2 1 Ribosome associated membrane protein RAMP4 EVI2A PF05399.6 ETS59829.1 - 0.051 12.8 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Mito_carr PF00153.22 ETS59831.1 - 6.7e-63 208.4 0.1 2.3e-21 75.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_22 PF03901.12 ETS59832.1 - 2.7e-70 237.4 0.0 3e-54 184.6 0.0 2.9 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family WD40 PF00400.27 ETS59833.1 - 1.1e-16 59.9 4.6 4.7e-06 26.2 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Vps26 PF03643.10 ETS59835.1 - 1.1e-130 434.3 4.3 1.5e-130 433.9 3.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Trm112p PF03966.11 ETS59835.1 - 5.1e-18 65.2 0.1 1.3e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 Trm112p-like protein Arrestin_C PF02752.17 ETS59835.1 - 0.024 14.7 0.2 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS59835.1 - 0.036 13.8 2.3 1.1 9.0 0.2 3.1 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain GPI-anchored PF10342.4 ETS59836.1 - 1.4e-07 31.8 0.0 2.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_H PF00075.19 ETS59837.1 - 4.7e-27 94.9 0.0 7.4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 ETS59837.1 - 4.8e-15 55.2 0.0 8.6e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Aminotran_3 PF00202.16 ETS59837.1 - 0.14 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III F5_F8_type_C PF00754.20 ETS59838.1 - 0.00017 21.4 0.0 0.00064 19.5 0.0 1.7 1 1 0 2 2 2 1 F5/8 type C domain SQS_PSY PF00494.14 ETS59840.1 - 6.5e-78 261.6 7.8 9.4e-78 261.1 5.4 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase PT-VENN PF04829.8 ETS59840.1 - 0.016 14.7 2.1 0.46 10.0 2.7 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif FAD_binding_1 PF00667.15 ETS59841.1 - 5.7e-56 189.3 0.0 9e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 ETS59841.1 - 8.9e-34 116.5 0.3 2.6e-33 115.0 0.2 1.9 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 ETS59841.1 - 7.4e-22 77.9 0.1 3.4e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF455 PF04305.9 ETS59841.1 - 0.011 15.0 0.0 0.06 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Flavodoxin_5 PF12724.2 ETS59841.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain ArfGap PF01412.13 ETS59842.1 - 9.6e-42 141.4 2.2 1.3e-41 141.0 1.5 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Med11 PF10280.4 ETS59843.1 - 2.5e-06 27.5 0.1 6.4e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Mediator complex protein ADSL_C PF10397.4 ETS59843.1 - 0.12 12.4 1.6 0.23 11.4 1.1 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus CENP-Q PF13094.1 ETS59843.1 - 0.39 10.7 7.8 0.35 10.8 2.9 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SPC22 PF04573.7 ETS59844.1 - 3.5e-40 137.0 0.4 4.2e-40 136.8 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit CASP_C PF08172.7 ETS59845.1 - 2.6e-66 223.1 6.4 2.6e-66 223.1 4.4 4.7 2 2 2 4 4 4 2 CASP C terminal DUF904 PF06005.7 ETS59845.1 - 0.041 14.1 0.1 0.041 14.1 0.1 7.8 6 3 0 6 6 6 0 Protein of unknown function (DUF904) DUF3450 PF11932.3 ETS59845.1 - 0.094 11.9 0.1 0.094 11.9 0.1 6.7 4 1 2 7 7 7 0 Protein of unknown function (DUF3450) WD40_alt PF14077.1 ETS59845.1 - 0.14 11.8 3.1 0.53 9.9 0.3 3.3 3 0 0 3 3 3 0 Alternative WD40 repeat motif CENP-F_leu_zip PF10473.4 ETS59845.1 - 0.23 11.3 70.6 0.058 13.2 13.5 6.1 4 2 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HTH_1 PF00126.22 ETS59845.1 - 3.1 7.5 13.9 0.033 13.9 1.7 3.6 3 2 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF1749 PF08538.5 ETS59846.1 - 1.7e-61 207.7 0.0 2e-59 200.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 ETS59846.1 - 1.1e-08 35.3 1.1 1.8e-08 34.5 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS59846.1 - 2.1e-07 30.8 0.0 1.4e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 ETS59846.1 - 0.00033 20.2 0.3 0.00082 19.0 0.1 1.6 2 0 0 2 2 2 1 Serine hydrolase Chlorophyllase2 PF12740.2 ETS59846.1 - 0.00086 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 ETS59846.1 - 0.0081 15.3 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF900 PF05990.7 ETS59846.1 - 0.01 15.1 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2305 PF10230.4 ETS59846.1 - 0.13 11.6 0.0 0.56 9.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF972 PF06156.8 ETS59847.1 - 0.042 14.1 19.2 0.25 11.6 0.7 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF972) DASH_Dam1 PF08653.5 ETS59847.1 - 0.047 13.4 0.9 0.5 10.1 0.4 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 Spectrin PF00435.16 ETS59847.1 - 0.9 9.8 21.6 1.6 9.0 0.6 4.0 4 0 0 4 4 4 0 Spectrin repeat TPR_MLP1_2 PF07926.7 ETS59847.1 - 1.9 8.2 23.9 0.88 9.3 0.8 3.7 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 ETS59847.1 - 9.1 5.8 25.8 7.6 6.0 0.3 3.4 3 0 0 3 3 3 0 IncA protein ABA_GPCR PF12430.3 ETS59848.1 - 1.3e-40 138.7 1.8 2.1e-40 137.9 1.3 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 ETS59848.1 - 1.4e-12 47.4 0.1 5.2e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) DASH_Duo1 PF08651.5 ETS59849.1 - 5.5e-23 80.3 0.2 9.3e-23 79.6 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 APG6 PF04111.7 ETS59849.1 - 0.65 8.9 0.0 0.65 8.9 0.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF572 PF04502.8 ETS59849.1 - 0.86 8.7 8.7 1.7 7.8 6.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF21 PF01595.15 ETS59851.1 - 3.7e-37 127.3 0.9 3.7e-37 127.3 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 ETS59851.1 - 5.8e-07 29.1 1.0 0.0098 15.6 0.0 2.8 3 0 0 3 3 3 2 CBS domain Aldo_ket_red PF00248.16 ETS59852.1 - 9.2e-66 221.5 0.0 1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pept_tRNA_hydro PF01195.14 ETS59853.1 - 3.9e-25 88.3 0.0 6.8e-21 74.5 0.0 2.4 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase Methyltransf_26 PF13659.1 ETS59853.1 - 2.3e-12 46.9 7.8 6e-12 45.6 3.4 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS59853.1 - 5e-12 45.6 0.0 9.3e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS59853.1 - 1.5e-07 32.0 0.1 6e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS59853.1 - 1.9e-06 28.1 0.1 1.2e-05 25.5 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.9 ETS59853.1 - 9e-06 25.1 0.0 2.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 ETS59853.1 - 0.00014 21.0 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.13 ETS59853.1 - 0.0013 18.2 0.0 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 ETS59853.1 - 0.0014 17.7 0.1 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 ETS59853.1 - 0.0043 16.4 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 ETS59853.1 - 0.013 15.9 0.0 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 ETS59853.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS59853.1 - 0.065 13.7 0.1 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Eco57I PF07669.6 ETS59853.1 - 0.17 12.2 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Ubie_methyltran PF01209.13 ETS59853.1 - 0.21 10.6 0.0 0.86 8.6 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ribosomal_S9 PF00380.14 ETS59856.1 - 2.9e-35 121.1 1.1 5.3e-35 120.2 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S9/S16 RFX_DNA_binding PF02257.10 ETS59857.1 - 5.4e-25 87.3 0.0 2.1e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 ETS59857.1 - 0.0077 16.4 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Poxvirus D5 protein-like BPL_LplA_LipB PF03099.14 ETS59858.1 - 9.6e-07 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PPR_2 PF13041.1 ETS59858.1 - 0.016 15.1 0.1 6.9 6.7 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family PPR PF01535.15 ETS59858.1 - 0.094 12.7 0.0 12 6.1 0.0 3.7 4 0 0 4 4 4 0 PPR repeat DEAD PF00270.24 ETS59859.1 - 4.2e-37 127.2 0.0 9.1e-37 126.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS59859.1 - 4.1e-19 68.2 0.0 8.5e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS59859.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETS59859.1 - 0.029 14.5 1.2 0.13 12.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain TEX19 PF15553.1 ETS59859.1 - 0.27 11.0 1.6 0.37 10.6 0.4 1.7 2 0 0 2 2 2 0 Testis-expressed protein 19 GWT1 PF06423.7 ETS59860.1 - 1.7e-39 135.0 0.0 3.8e-39 133.8 0.0 1.7 1 0 0 1 1 1 1 GWT1 Exo_endo_phos PF03372.18 ETS59861.1 - 1.4e-23 84.1 2.1 9.3e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family MHYT PF03707.11 ETS59863.1 - 1.6e-10 40.9 20.7 5.7e-05 23.1 4.0 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Med14 PF08638.6 ETS59864.1 - 1.2e-49 168.2 0.0 2.2e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 DnaJ PF00226.26 ETS59865.1 - 1.6e-15 56.5 0.9 1.6e-15 56.5 0.6 1.7 2 0 0 2 2 2 1 DnaJ domain eIF-3c_N PF05470.7 ETS59866.1 - 2.6e-179 597.1 17.8 2.6e-179 597.1 12.4 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 ETS59866.1 - 8.7e-15 54.9 0.0 2.4e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain FeoC PF09012.5 ETS59866.1 - 0.069 12.8 0.0 0.3 10.8 0.0 2.1 1 0 0 1 1 1 0 FeoC like transcriptional regulator BNIP2 PF12496.3 ETS59866.1 - 4.6 7.4 14.3 18 5.4 9.9 2.0 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 OSCP PF00213.13 ETS59867.1 - 5.8e-36 123.9 2.8 6.8e-36 123.7 1.9 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Zot PF05707.7 ETS59867.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) GST_N_3 PF13417.1 ETS59868.1 - 2.1e-11 43.8 0.0 4.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS59868.1 - 4.6e-10 39.5 0.0 9.8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS59868.1 - 1.5e-09 37.6 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS59868.1 - 2e-09 37.2 0.0 4.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS59868.1 - 1.4e-07 31.3 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS59868.1 - 0.0036 17.7 0.0 0.0073 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.13 ETS59869.1 - 6.1e-49 166.4 0.0 9e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glycos_transf_2 PF00535.21 ETS59871.1 - 3e-26 92.0 0.0 4.3e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ETS59871.1 - 4.9e-09 36.3 0.0 6.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyoxalase PF00903.20 ETS59872.1 - 3.1e-23 82.1 0.2 4.3e-23 81.6 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS59872.1 - 4.5e-17 62.6 0.0 7.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 ETS59872.1 - 2.3e-09 37.2 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 ETS59872.1 - 6.2e-05 22.9 0.0 0.02 14.8 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase-like domain WD40 PF00400.27 ETS59873.1 - 6.4e-32 108.2 6.2 1.7e-08 34.0 0.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 ETS59873.1 - 1.1e-24 87.0 0.0 1.9e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS59873.1 - 5.5e-12 45.4 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.6 ETS59873.1 - 5.7e-08 31.9 0.4 0.0061 15.3 0.1 3.4 2 2 1 3 3 3 3 Nup133 N terminal like RNA_pol_Rpc34 PF05158.7 ETS59874.1 - 5.8e-80 268.9 1.6 6.8e-70 235.8 0.1 2.2 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit TrmB PF01978.14 ETS59874.1 - 0.0015 18.1 1.1 0.007 16.0 0.1 2.6 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 ETS59874.1 - 0.012 15.4 0.3 0.035 13.9 0.2 1.7 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MarR PF01047.17 ETS59874.1 - 0.023 14.4 0.1 0.059 13.0 0.1 1.7 1 0 0 1 1 1 0 MarR family Penicillinase_R PF03965.11 ETS59874.1 - 0.12 12.4 1.7 1.9 8.5 0.1 2.5 1 1 1 2 2 2 0 Penicillinase repressor Glyco_hydro_45 PF02015.11 ETS59875.1 - 9.8e-79 264.0 16.4 1.7e-78 263.3 11.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 FAD_binding_3 PF01494.14 ETS59876.1 - 2.7e-21 76.0 0.8 2.6e-18 66.2 0.6 3.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS59876.1 - 3.4e-07 30.5 0.1 4.5e-06 26.9 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS59876.1 - 7.4e-05 22.6 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS59876.1 - 8.4e-05 21.6 0.1 0.00018 20.5 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS59876.1 - 0.00034 19.1 0.0 0.00087 17.8 0.0 1.7 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 ETS59876.1 - 0.0007 19.2 0.0 0.0027 17.3 0.0 2.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.27 ETS59876.1 - 0.0025 17.6 0.2 1.6 8.7 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat GIDA PF01134.17 ETS59876.1 - 0.003 16.5 1.0 0.0034 16.3 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETS59876.1 - 0.0083 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS59876.1 - 0.043 13.3 0.3 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 ETS59876.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 ETS59876.1 - 0.088 12.1 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 ETS59876.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 ETS59876.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.5 ETS59876.1 - 0.13 11.1 0.0 0.61 8.8 0.0 2.1 2 1 0 2 2 2 0 Squalene epoxidase ARGLU PF15346.1 ETS59876.1 - 0.21 11.3 9.5 0.044 13.5 3.0 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF2408 PF10303.4 ETS59876.1 - 0.35 10.9 0.8 0.93 9.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DMPK_coil PF08826.5 ETS59876.1 - 0.55 10.1 4.9 1.3 8.9 3.4 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF3534 PF12053.3 ETS59877.1 - 0.023 14.5 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) NUDE_C PF04880.8 ETS59878.1 - 0.15 12.4 4.6 0.21 11.9 3.2 1.3 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Acyl_transf_3 PF01757.17 ETS59879.1 - 8.8e-35 120.1 28.7 8.8e-35 120.1 19.9 3.1 3 0 0 3 3 3 1 Acyltransferase family Glyco_trans_2_3 PF13632.1 ETS59879.1 - 1.2e-26 93.6 5.4 1.2e-26 93.6 3.8 4.2 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS59879.1 - 1.2e-17 64.4 0.0 2.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fumarate_red_C PF02300.12 ETS59880.1 - 0.92 9.3 8.3 0.27 11.1 3.4 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit C Cellulase PF00150.13 ETS59881.1 - 0.00012 21.3 0.1 0.24 10.5 0.0 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 ETS59882.1 - 9.4e-41 139.6 0.0 1.4e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS59882.1 - 2.1e-25 89.2 0.0 3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3275 PF11679.3 ETS59882.1 - 5.1 6.6 6.1 2.7 7.5 1.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) CAP_GLY PF01302.20 ETS59883.1 - 1.9e-17 62.7 0.5 2.9e-17 62.0 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain PI3_PI4_kinase PF00454.22 ETS59884.1 - 6.1e-37 127.3 0.0 1e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pkinase PF00069.20 ETS59885.1 - 1.3e-32 112.9 0.0 3.5e-26 91.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETS59885.1 - 1.1e-16 60.6 0.0 7.9e-14 51.3 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS59885.1 - 4.1e-05 22.6 0.0 7.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETS59885.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pex16 PF08610.5 ETS59886.1 - 1.9e-74 250.7 0.1 2.8e-71 240.2 0.1 2.8 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pkinase PF00069.20 ETS59887.1 - 7.1e-56 189.2 0.0 9.1e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS59887.1 - 1.2e-39 135.9 0.0 1.6e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS59887.1 - 3.8e-06 26.0 0.0 7.2e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Prominin PF05478.6 ETS59887.1 - 0.12 9.8 0.0 0.17 9.4 0.0 1.1 1 0 0 1 1 1 0 Prominin MmgE_PrpD PF03972.9 ETS59888.1 - 8.4e-149 495.5 0.0 1.6e-148 494.6 0.0 1.4 1 0 0 1 1 1 1 MmgE/PrpD family VitD-bind_III PF09164.5 ETS59888.1 - 0.22 11.1 0.7 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Vitamin D binding protein, domain III DUF3425 PF11905.3 ETS59889.1 - 5.9e-19 68.3 0.4 1.1e-18 67.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS59889.1 - 0.31 11.0 6.0 0.61 10.0 4.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor PPR_2 PF13041.1 ETS59890.1 - 1.1e-09 38.1 0.1 0.007 16.3 0.0 5.9 6 1 1 7 7 7 3 PPR repeat family PPR PF01535.15 ETS59890.1 - 0.00011 21.8 3.1 14 5.9 0.0 6.5 8 0 0 8 8 8 1 PPR repeat PPR_3 PF13812.1 ETS59890.1 - 0.0023 18.0 8.1 26 5.4 0.0 7.9 10 0 0 10 10 10 2 Pentatricopeptide repeat domain KH_1 PF00013.24 ETS59891.1 - 8.3e-79 259.1 24.2 7e-12 44.8 0.0 13.7 15 0 0 15 15 15 10 KH domain KH_3 PF13014.1 ETS59891.1 - 5.8e-54 178.9 18.2 5.2e-07 29.1 0.4 14.0 14 0 0 14 14 14 8 KH domain DUF4112 PF13430.1 ETS59891.1 - 2.9e-27 94.6 0.6 6.6e-27 93.5 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MFS_1 PF07690.11 ETS59891.1 - 2.7e-22 78.9 42.8 3.5e-13 48.9 16.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily KH_2 PF07650.12 ETS59891.1 - 3.9e-13 48.7 20.6 0.024 14.1 0.3 9.3 10 0 0 10 10 10 5 KH domain KH_4 PF13083.1 ETS59891.1 - 3.7e-05 23.2 17.0 0.22 11.2 0.0 7.3 6 1 2 8 8 8 2 KH domain SLS PF14611.1 ETS59891.1 - 0.016 14.6 11.4 1.4 8.3 0.1 6.4 7 1 1 8 8 8 0 Mitochondrial inner-membrane-bound regulator OATP PF03137.15 ETS59891.1 - 1.1 7.2 8.6 0.32 9.0 1.7 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NPBW PF15180.1 ETS59892.1 - 0.046 13.3 0.0 0.062 12.9 0.0 1.3 1 1 0 1 1 1 0 Neuropeptides B and W Sugar_tr PF00083.19 ETS59893.1 - 3.4e-104 348.9 28.2 3.9e-104 348.7 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS59893.1 - 9.8e-18 63.9 45.0 7.4e-16 57.7 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GWT1 PF06423.7 ETS59893.1 - 0.0021 18.1 3.5 0.22 11.5 0.0 3.1 2 1 1 3 3 3 2 GWT1 CAP59_mtransfer PF11735.3 ETS59894.1 - 3.8e-70 235.8 0.0 5.4e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4637 PF15470.1 ETS59895.1 - 3.4 7.2 5.3 1.4 8.4 1.2 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4637) MFS_1 PF07690.11 ETS59896.1 - 3.3e-28 98.4 32.5 3.3e-28 98.4 22.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS59896.1 - 0.00019 19.7 2.5 0.00032 19.0 1.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2238 PF09997.4 ETS59896.1 - 0.33 10.3 5.3 0.36 10.2 0.7 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) Sulf_transp PF04143.9 ETS59897.1 - 1.2e-14 54.0 16.6 3.4e-10 39.7 3.2 4.4 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 ETS59897.1 - 4.9e-09 35.7 2.8 4.9e-09 35.7 2.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4341) Sugar_tr PF00083.19 ETS59898.1 - 2.2e-50 171.5 11.3 3.1e-50 171.0 7.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS59898.1 - 9.3e-13 47.6 23.9 1.4e-12 47.0 16.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HLH PF00010.21 ETS59898.1 - 2.1e-05 24.1 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Transaldolase PF00923.14 ETS59899.1 - 1.8e-32 112.6 0.0 2.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Transaldolase His_Phos_2 PF00328.17 ETS59900.1 - 2.3e-32 112.6 0.0 2.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.18 ETS59901.1 - 4.9e-06 26.6 0.3 6.4e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rad1 PF02144.11 ETS59902.1 - 1.4e-94 315.9 0.0 1.7e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AvrE PF11725.3 ETS59902.1 - 1.4 5.8 5.1 1.7 5.5 3.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF2236 PF09995.4 ETS59903.1 - 6e-26 91.2 3.9 9.4e-26 90.5 0.2 2.7 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) PriCT_2 PF08707.6 ETS59903.1 - 0.0058 16.4 0.0 0.042 13.7 0.0 2.5 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) BP28CT PF08146.7 ETS59905.1 - 7.2e-38 129.7 0.5 9.6e-37 126.0 0.0 3.2 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 ETS59905.1 - 1.1e-17 64.1 4.6 1.1e-17 64.1 3.2 4.9 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.1 ETS59905.1 - 0.00036 20.9 30.6 0.015 15.8 0.1 8.8 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.17 ETS59905.1 - 0.011 15.7 0.8 0.011 15.7 0.6 6.6 8 0 0 8 8 8 0 HEAT repeat DASH_Spc19 PF08287.6 ETS59908.1 - 7.8e-27 93.7 4.5 1.3e-26 92.9 3.1 1.4 1 1 0 1 1 1 1 Spc19 MscS_porin PF12795.2 ETS59908.1 - 0.016 14.5 8.3 0.026 13.8 5.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain OmpH PF03938.9 ETS59908.1 - 0.021 14.7 1.3 0.035 14.0 0.9 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.7 ETS59908.1 - 0.03 14.6 6.4 5 7.5 0.0 3.2 3 0 0 3 3 3 0 SlyX Gp-FAR-1 PF05823.7 ETS59908.1 - 0.031 14.2 1.9 0.63 9.9 0.0 2.2 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Phage_GPO PF05929.6 ETS59908.1 - 0.075 12.2 0.5 0.11 11.7 0.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase tRNA-synt_His PF13393.1 ETS59908.1 - 0.079 12.0 2.2 0.099 11.6 1.5 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Topo-VIb_trans PF09239.6 ETS59908.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer BRE1 PF08647.6 ETS59908.1 - 0.16 11.9 2.2 0.21 11.5 0.8 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase FUSC PF04632.7 ETS59908.1 - 0.16 10.4 10.7 0.18 10.1 7.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4515 PF14988.1 ETS59908.1 - 0.17 11.5 5.7 0.024 14.2 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) PilJ PF13675.1 ETS59908.1 - 0.19 12.0 5.0 0.32 11.3 2.8 1.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term YfcL PF08891.6 ETS59908.1 - 0.32 11.0 0.1 0.32 11.0 0.0 2.0 3 1 0 3 3 3 0 YfcL protein DUF4140 PF13600.1 ETS59908.1 - 1.6 9.2 11.0 2.5 8.5 0.7 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 ETS59908.1 - 4.3 6.9 7.1 11 5.6 0.5 2.4 2 0 0 2 2 2 0 Septum formation initiator GRAM PF02893.15 ETS59909.1 - 2.7e-17 62.0 0.1 8.3e-17 60.4 0.0 1.9 2 0 0 2 2 2 1 GRAM domain Wbp11 PF09429.5 ETS59910.1 - 2.7e-12 46.4 16.7 2.7e-12 46.4 11.6 2.8 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.2 ETS59910.1 - 4.4e-12 46.2 9.6 4.4e-12 46.2 6.7 3.3 2 2 0 2 2 2 1 mRNA biogenesis factor Peptidase_C48 PF02902.14 ETS59910.1 - 2e-11 43.9 0.1 5.7e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF3450 PF11932.3 ETS59910.1 - 0.01 15.1 8.6 0.017 14.4 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 ETS59910.1 - 0.32 10.5 7.1 0.77 9.3 4.9 1.6 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 ETS59910.1 - 0.4 9.6 4.7 0.66 8.9 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETS59910.1 - 2.5 7.7 10.0 5.1 6.7 7.0 1.4 1 0 0 1 1 1 0 Mnd1 family Tho2 PF11262.3 ETS59910.1 - 5.6 5.9 4.3 8.8 5.2 3.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Acyltransferase PF01553.16 ETS59911.1 - 1.4e-11 43.9 0.0 4.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Acyltransferase TTL PF03133.10 ETS59912.1 - 4e-46 157.2 0.0 1.1e-45 155.7 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Nro1 PF12753.2 ETS59912.1 - 0.0047 15.9 2.1 0.0069 15.3 1.5 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 OmpH PF03938.9 ETS59913.1 - 7.3 6.5 16.6 0.26 11.2 7.3 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.2 ETS59914.1 - 3.6e-13 49.6 0.6 3.4e-11 43.3 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS59914.1 - 7.5e-11 41.9 2.8 1e-06 28.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS59914.1 - 1.5e-09 37.1 0.3 0.018 14.8 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETS59914.1 - 1.4e-07 31.8 2.5 0.0012 19.2 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS59914.1 - 4.8e-06 26.2 1.3 0.19 12.0 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Nrap PF03813.9 ETS59915.1 - 4.8e-246 818.8 0.0 5.8e-246 818.5 0.0 1.0 1 0 0 1 1 1 1 Nrap protein NTP_transf_2 PF01909.18 ETS59915.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PI31_Prot_N PF11566.3 ETS59916.1 - 2.1e-28 98.8 0.0 2.9e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 ETS59916.1 - 1.5e-12 47.9 19.2 1.5e-12 47.9 13.3 3.5 3 0 0 3 3 3 1 PI31 proteasome regulator Adaptin_N PF01602.15 ETS59917.1 - 2.4e-100 336.3 8.1 3.7e-100 335.7 5.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 ETS59917.1 - 7e-66 219.8 0.0 2e-65 218.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 ETS59917.1 - 5.9e-62 207.4 0.3 1.6e-61 206.1 0.1 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 ETS59917.1 - 2.7e-14 53.1 4.6 0.00025 21.2 0.0 5.1 1 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 ETS59917.1 - 2.9e-09 37.0 6.7 0.00089 19.1 0.0 4.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 ETS59917.1 - 4.9e-07 29.2 0.2 0.007 16.3 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 ETS59917.1 - 0.0012 19.2 0.2 3.4 8.2 0.0 4.8 5 1 0 5 5 3 1 HEAT-like repeat DUF3810 PF12725.2 ETS59917.1 - 0.0061 15.4 0.1 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Cullin PF00888.17 ETS59917.1 - 0.0095 14.5 1.0 0.13 10.7 0.1 2.2 2 0 0 2 2 2 1 Cullin family ParcG PF10274.4 ETS59917.1 - 0.014 15.3 2.9 0.47 10.3 0.0 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Arm PF00514.18 ETS59917.1 - 0.75 9.7 4.3 84 3.2 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MutS_V PF00488.16 ETS59918.1 - 4.2e-78 261.9 0.0 6.1e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS59918.1 - 5e-39 134.2 0.6 3.2e-38 131.5 0.1 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 ETS59918.1 - 5.6e-34 116.5 0.0 1.2e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I zf-C2H2_3 PF13878.1 ETS59918.1 - 1.1e-12 47.2 1.6 2.4e-12 46.1 1.1 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.1 ETS59918.1 - 1.7e-12 46.8 0.0 5.6e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_II PF05188.12 ETS59918.1 - 1.7e-10 41.0 0.0 7.7e-10 38.9 0.0 2.2 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 ETS59918.1 - 1.2e-06 28.6 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Sec63 PF02889.11 ETS59919.1 - 1.7e-42 145.7 0.0 3e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 ETS59919.1 - 1.7e-23 82.9 0.0 4.8e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS59919.1 - 2.2e-13 49.8 0.0 4.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS59919.1 - 2.7e-07 30.5 0.0 5.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETS59919.1 - 0.0066 16.1 0.4 0.043 13.5 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain HHH_5 PF14520.1 ETS59919.1 - 0.011 15.9 0.0 0.037 14.2 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain Enolase_C PF00113.17 ETS59920.1 - 1.4e-143 477.2 0.1 1.9e-143 476.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 ETS59920.1 - 3.7e-58 195.1 0.0 6e-58 194.4 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 ETS59920.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 ETS59920.1 - 0.008 16.6 0.0 0.016 15.7 0.0 1.6 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 ETS59920.1 - 0.047 12.6 0.1 0.1 11.5 0.1 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus EMP24_GP25L PF01105.19 ETS59921.1 - 2.7e-40 138.0 0.1 3.2e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2607 PF10795.4 ETS59921.1 - 0.12 12.2 0.6 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) Josephin PF02099.12 ETS59922.1 - 1.8e-53 180.3 0.1 3.5e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Josephin UIM PF02809.15 ETS59922.1 - 0.00034 19.9 30.4 0.038 13.5 0.9 4.6 5 0 0 5 5 5 3 Ubiquitin interaction motif DUF4654 PF15547.1 ETS59922.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4654) ATG27 PF09451.5 ETS59923.1 - 1.9e-79 266.6 0.0 2.2e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Myb_DNA-bind_6 PF13921.1 ETS59924.1 - 0.0016 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 ETS59924.1 - 0.0044 16.8 0.4 0.12 12.2 0.3 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain ABC_tran PF00005.22 ETS59925.1 - 8.6e-34 116.7 0.1 2.6e-16 60.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 ETS59925.1 - 3.8e-14 51.9 5.8 3.8e-14 51.9 4.0 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 ETS59925.1 - 4.4e-13 49.8 7.4 0.0056 16.6 0.0 4.3 2 2 1 4 4 4 4 AAA domain SMC_N PF02463.14 ETS59925.1 - 4.8e-11 42.3 5.5 0.00017 20.9 0.4 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 ETS59925.1 - 2.9e-07 29.9 3.5 2 7.3 0.1 4.8 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 ETS59925.1 - 5.9e-07 29.6 0.0 0.00074 19.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 ETS59925.1 - 9.9e-06 25.7 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 ETS59925.1 - 1.9e-05 23.8 2.2 0.16 11.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS59925.1 - 2.4e-05 23.7 1.0 0.04 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.22 ETS59925.1 - 4.9e-05 22.7 2.9 4.9e-05 22.7 2.0 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_17 PF13207.1 ETS59925.1 - 9.3e-05 23.2 0.6 0.82 10.5 0.2 2.8 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 ETS59925.1 - 0.00018 21.1 1.4 0.018 14.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 ETS59925.1 - 0.00025 21.5 0.0 0.4 11.2 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein AAA_16 PF13191.1 ETS59925.1 - 0.00027 20.9 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 ETS59925.1 - 0.0004 20.5 0.3 0.16 12.1 0.0 3.1 3 0 0 3 3 2 1 RNA helicase VirE PF05272.6 ETS59925.1 - 0.00041 19.8 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E AAA_33 PF13671.1 ETS59925.1 - 0.001 18.9 0.4 0.11 12.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 ETS59925.1 - 0.0011 18.6 0.9 0.34 10.6 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 ETS59925.1 - 0.0012 18.2 0.1 0.89 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 ETS59925.1 - 0.0024 18.1 8.2 0.0084 16.4 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 ETS59925.1 - 0.0025 17.5 11.0 0.007 16.1 1.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 ETS59925.1 - 0.0028 17.4 11.2 0.0061 16.3 7.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain SbcCD_C PF13558.1 ETS59925.1 - 0.0031 17.3 0.0 2.2 8.2 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 ETS59925.1 - 0.0032 17.0 0.4 0.042 13.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 ETS59925.1 - 0.0056 16.1 2.8 0.23 10.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 ETS59925.1 - 0.006 16.8 3.1 1.1 9.6 0.1 3.3 2 2 1 3 3 3 1 AAA domain AAA_28 PF13521.1 ETS59925.1 - 0.0093 15.9 0.5 1.6 8.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 ETS59925.1 - 0.017 15.4 1.9 0.017 15.4 1.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 ETS59925.1 - 0.026 14.3 1.9 0.026 14.3 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 ETS59925.1 - 0.027 13.3 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 ETS59925.1 - 0.032 14.5 1.0 0.032 14.5 0.7 2.5 2 1 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 ETS59925.1 - 0.047 14.4 0.2 0.047 14.4 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_24 PF13479.1 ETS59925.1 - 0.055 13.0 0.6 0.98 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETS59925.1 - 0.056 13.3 1.8 13 5.6 0.0 3.3 3 1 1 4 4 3 0 AAA domain Thymidylate_kin PF02223.12 ETS59925.1 - 0.073 12.4 0.7 4.5 6.5 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Rad17 PF03215.10 ETS59925.1 - 0.083 11.5 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 ETS59925.1 - 0.097 12.0 1.0 6 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain HflK_N PF12221.3 ETS59925.1 - 0.11 12.2 0.1 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal AAA_5 PF07728.9 ETS59925.1 - 0.16 11.6 1.4 2.4 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 ETS59925.1 - 0.17 10.6 0.3 1 8.0 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Fer4_8 PF13183.1 ETS59925.1 - 0.31 11.1 9.2 0.31 11.0 1.2 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 ETS59925.1 - 0.34 10.3 1.7 1.8 8.0 0.0 2.9 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 ETS59925.1 - 0.47 10.1 2.1 8.4 6.0 0.0 3.0 3 0 0 3 3 3 0 NTPase Fer4_2 PF12797.2 ETS59925.1 - 0.56 10.2 12.7 0.23 11.4 1.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain zf-RING_2 PF13639.1 ETS59927.1 - 9.1e-11 41.4 6.2 5.8e-09 35.6 2.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 ETS59927.1 - 1.5e-10 41.0 1.3 1.4e-08 34.7 0.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETS59927.1 - 7.6e-06 25.5 4.5 1.5e-05 24.5 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS59927.1 - 9.7e-06 25.1 3.3 3.3e-05 23.4 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS59927.1 - 3.6e-05 23.6 1.5 3.6e-05 23.6 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS59927.1 - 0.00013 21.7 0.5 0.00041 20.1 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 ETS59927.1 - 0.00045 19.8 2.0 0.00067 19.3 0.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS59927.1 - 0.055 13.2 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 ETS59927.1 - 0.2 11.2 3.0 0.11 12.1 0.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 ETS59927.1 - 0.35 10.9 2.4 0.63 10.0 1.7 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 ETS59927.1 - 0.54 10.2 3.4 0.99 9.4 0.7 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain DEC-1_N PF04625.8 ETS59927.1 - 1.9 7.0 12.3 3.3 6.2 8.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RINGv PF12906.2 ETS59927.1 - 2 8.5 6.0 0.48 10.5 1.4 1.9 2 0 0 2 2 2 0 RING-variant domain Ribosomal_L7Ae PF01248.21 ETS59928.1 - 9.8e-24 82.6 0.2 2e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 ETS59928.1 - 0.0026 17.6 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PBP PF01161.15 ETS59930.1 - 1.6e-15 57.1 0.1 2.7e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.27 ETS59931.1 - 1.7e-26 91.0 18.0 6e-08 32.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETS59931.1 - 1.1e-05 23.8 0.1 0.021 13.0 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETS59931.1 - 0.015 14.7 0.4 0.11 11.9 0.1 2.1 1 1 1 2 2 2 0 PQQ-like domain PQQ_3 PF13570.1 ETS59931.1 - 0.19 12.0 3.7 42 4.6 0.0 4.4 6 0 0 6 6 6 0 PQQ-like domain Clr2 PF10383.4 ETS59932.1 - 4.3e-21 75.3 0.0 8.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 WW PF00397.21 ETS59932.1 - 4.5e-08 32.8 1.8 9e-08 31.8 1.2 1.5 1 0 0 1 1 1 1 WW domain DUF4611 PF15387.1 ETS59932.1 - 0.013 15.6 2.6 0.05 13.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HIG_1_N PF04588.8 ETS59932.1 - 0.37 10.5 2.3 0.29 10.9 0.1 1.9 2 0 0 2 2 2 0 Hypoxia induced protein conserved region Med3 PF11593.3 ETS59932.1 - 9.3 5.3 11.7 19 4.3 8.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DNA_primase_S PF01896.14 ETS59933.1 - 1.3e-52 177.5 0.0 2.4e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Ist1 PF03398.9 ETS59934.1 - 4.4e-53 179.0 1.4 5.6e-53 178.7 1.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DnaJ PF00226.26 ETS59935.1 - 1.8e-20 72.4 0.4 1e-19 69.9 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain DIT1_PvcA PF05141.7 ETS59935.1 - 0.1 11.8 3.5 0.17 11.1 2.4 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein SAPS PF04499.10 ETS59935.1 - 0.19 10.3 2.8 0.26 9.8 1.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RrnaAD PF00398.15 ETS59936.1 - 2e-19 69.6 0.0 4.6e-19 68.4 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pam17 PF08566.5 ETS59937.1 - 7.5e-69 230.8 0.0 9.6e-69 230.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DEAD PF00270.24 ETS59938.1 - 4.4e-41 140.1 0.2 6.6e-41 139.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS59938.1 - 6.5e-24 83.6 0.1 1.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 ETS59938.1 - 0.0039 16.3 0.1 0.009 15.1 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF221 PF02714.10 ETS59939.1 - 7.8e-100 333.8 18.3 1.6e-99 332.9 12.7 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS59939.1 - 3.2e-32 111.2 0.4 3.2e-32 111.2 0.3 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 ETS59939.1 - 2.1e-09 37.7 0.0 4.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 ETS59939.1 - 0.22 11.5 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.16 ETS59941.1 - 1.1e-129 432.9 39.6 1.2e-129 432.7 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS59941.1 - 3.6e-41 141.0 42.4 4.7e-41 140.7 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease IBR PF01485.16 ETS59942.1 - 4.7e-20 71.2 43.8 6.8e-12 45.0 3.0 4.5 3 1 1 4 4 4 2 IBR domain zf-RING_UBOX PF13445.1 ETS59942.1 - 0.00024 20.7 20.0 0.0018 17.9 0.5 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.1 ETS59942.1 - 0.00035 20.5 4.6 0.00035 20.5 3.2 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS59942.1 - 0.00072 19.3 5.3 0.00072 19.3 3.7 4.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 ETS59942.1 - 0.00091 18.8 5.3 0.00091 18.8 3.6 4.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) DUF1488 PF07369.6 ETS59942.1 - 0.061 13.1 0.1 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) zf-C3HC4_4 PF15227.1 ETS59942.1 - 0.17 11.7 25.5 0.14 12.0 0.3 4.4 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETS59942.1 - 2.2 8.0 40.7 0.067 12.9 3.8 4.3 3 1 1 4 4 4 0 zinc-RING finger domain Ribosomal_L16 PF00252.13 ETS59943.1 - 7e-31 106.7 0.1 9.3e-31 106.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L18e PF00828.14 ETS59944.1 - 1.4e-32 112.7 0.1 2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Hexapep PF00132.19 ETS59945.1 - 2.4e-12 45.7 11.5 1.4e-07 30.6 0.5 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS59945.1 - 1.4e-05 24.5 9.2 0.017 14.6 0.2 3.1 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 ETS59945.1 - 0.098 11.2 2.4 1.5 7.3 0.5 2.2 1 1 1 2 2 2 0 L-fucokinase ATP_transf PF09830.4 ETS59946.1 - 8.4e-07 28.6 0.0 2.4e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4134 PF13572.1 ETS59947.1 - 0.39 10.8 7.8 0.62 10.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) Metallophos PF00149.23 ETS59948.1 - 3.7e-09 36.2 0.4 9.5e-09 34.9 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 ETS59950.1 - 1.1e-30 104.9 0.0 4.8e-19 67.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS59950.1 - 1.2e-20 73.2 0.1 1.9e-12 46.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS59950.1 - 8e-13 48.0 0.0 1.5e-05 24.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 ETS59950.1 - 1.2e-09 37.7 2.5 1.4e-05 24.6 0.1 3.5 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 ETS59950.1 - 1.4e-05 24.7 0.1 0.066 12.9 0.0 2.7 2 0 0 2 2 2 2 Limkain b1 Cytochrom_B561 PF03188.11 ETS59951.1 - 3.5e-13 49.5 6.3 3.5e-13 49.5 4.4 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 ETS59951.1 - 0.0055 16.0 25.9 0.014 14.7 2.5 3.2 2 1 1 3 3 3 2 Cytochrome b(N-terminal)/b6/petB DUF2306 PF10067.4 ETS59951.1 - 0.0062 16.6 2.3 0.0062 16.6 1.6 3.1 2 1 1 3 3 3 1 Predicted membrane protein (DUF2306) Sdh_cyt PF01127.17 ETS59951.1 - 0.02 14.7 4.8 0.02 14.7 3.3 3.0 1 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM_1 PF13172.1 ETS59951.1 - 0.031 14.0 0.3 0.031 14.0 0.2 3.0 3 1 0 3 3 3 0 PepSY-associated TM helix DUF939 PF06081.6 ETS59951.1 - 0.09 12.6 5.9 3.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF939) DUF2678 PF10856.3 ETS59951.1 - 0.13 11.9 2.0 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) SecY PF00344.15 ETS59951.1 - 0.16 10.8 4.9 0.65 8.8 3.4 1.9 1 1 0 1 1 1 0 SecY translocase DUF1129 PF06570.6 ETS59951.1 - 4.2 6.6 9.2 1 8.6 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Grp1_Fun34_YaaH PF01184.14 ETS59952.1 - 1.5e-29 102.7 20.3 2e-29 102.3 14.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 5-FTHF_cyc-lig PF01812.15 ETS59953.1 - 3.2e-36 124.8 0.0 3.9e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family NIT PF08376.5 ETS59953.1 - 0.0064 16.0 0.1 0.018 14.5 0.1 1.7 2 0 0 2 2 2 1 Nitrate and nitrite sensing Pribosyltran_N PF13793.1 ETS59954.1 - 1.9e-43 146.9 0.0 2.6e-42 143.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 ETS59954.1 - 1.9e-36 125.5 0.7 5.5e-32 111.0 0.2 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 ETS59954.1 - 2.5e-15 56.3 0.1 3.9e-09 36.2 0.1 3.0 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.1 ETS59954.1 - 0.0074 15.5 0.1 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase PF00069.20 ETS59955.1 - 3.7e-73 245.8 0.0 4.9e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS59955.1 - 9.9e-34 116.5 0.0 2.3e-33 115.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS59955.1 - 0.00064 18.7 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS59955.1 - 0.01 15.6 0.1 0.035 13.8 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 ETS59955.1 - 0.014 14.4 0.1 0.032 13.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spc97_Spc98 PF04130.8 ETS59957.1 - 1.1e-47 162.6 0.0 1.7e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DNA_pol_phi PF04931.8 ETS59957.1 - 1.1 6.8 14.8 2.7 5.6 10.3 1.5 1 0 0 1 1 1 0 DNA polymerase phi DUF4050 PF13259.1 ETS59957.1 - 2.1 8.2 9.3 0.079 12.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) MOZ_SAS PF01853.13 ETS59958.1 - 3.4e-78 261.2 0.0 5.1e-78 260.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 ETS59958.1 - 1.4e-16 59.9 24.9 9.4e-10 38.0 6.1 3.2 2 1 1 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 ETS59958.1 - 4 6.7 15.2 0.71 9.1 3.4 2.8 2 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Profilin PF00235.14 ETS59959.1 - 3.2e-36 124.1 0.2 3.5e-36 123.9 0.1 1.0 1 0 0 1 1 1 1 Profilin TIM PF00121.13 ETS59960.1 - 5e-96 320.4 0.8 6e-96 320.2 0.6 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 ETS59960.1 - 0.00023 20.4 0.1 0.0012 18.1 0.0 1.9 1 1 1 2 2 2 1 CutC family Thiolase_N PF00108.18 ETS59961.1 - 1.4e-82 276.6 0.8 1.4e-82 276.6 0.6 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS59961.1 - 2.1e-48 162.8 0.4 2.1e-48 162.8 0.3 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 ETS59961.1 - 1.8e-05 24.3 1.1 5.7e-05 22.7 0.8 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain bZIP_1 PF00170.16 ETS59962.1 - 0.00027 20.8 16.7 0.00054 19.8 11.1 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 ETS59962.1 - 0.26 11.6 13.9 0.45 10.8 9.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 ETS59962.1 - 2 6.1 3.4 2.7 5.7 2.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_S21 PF01165.15 ETS59964.1 - 0.092 12.2 1.0 0.17 11.3 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 zf-UBR PF02207.15 ETS59966.1 - 2.4e-12 46.3 9.7 2.4e-12 46.3 6.7 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 ETS59966.1 - 5.8e-05 22.7 0.9 5.8e-05 22.7 0.6 3.9 4 1 1 5 5 5 1 PHD-finger C1_3 PF07649.7 ETS59966.1 - 1 9.4 9.9 15 5.7 0.4 3.7 3 0 0 3 3 3 0 C1-like domain Pyrid_oxidase_2 PF13883.1 ETS59967.1 - 8.2e-26 90.7 0.1 1.1e-25 90.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rad51 PF08423.6 ETS59968.1 - 3.8e-138 458.5 0.1 4.6e-138 458.2 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 ETS59968.1 - 3.4e-15 55.9 0.0 4.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 ETS59968.1 - 1.2e-08 34.4 0.1 1.7e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 ETS59968.1 - 1.9e-08 34.3 0.2 4.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 ETS59968.1 - 2.2e-07 30.2 0.0 3.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 ETS59968.1 - 0.026 13.4 0.0 0.073 11.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 ETS59968.1 - 0.048 12.4 1.0 0.17 10.7 0.4 1.8 1 1 1 2 2 2 0 PAXNEB protein HHH PF00633.18 ETS59968.1 - 0.062 13.0 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PNRC PF15365.1 ETS59969.1 - 7.6e-08 32.2 0.8 7.6e-08 32.2 0.5 3.1 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator CBFD_NFYB_HMF PF00808.18 ETS59970.1 - 2.4e-09 37.1 0.1 4.5e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VRR_NUC PF08774.6 ETS59971.1 - 8.4e-20 70.6 0.0 1.9e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain ArgK PF03308.11 ETS59971.1 - 0.12 11.1 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Myosin_head PF00063.16 ETS59972.1 - 2.4e-250 832.3 0.0 2.4e-250 832.3 0.0 3.8 2 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 ETS59972.1 - 1.4e-13 49.6 69.4 1.4e-13 49.6 48.1 5.3 3 1 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 ETS59972.1 - 7.6e-07 28.7 0.1 2e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 ETS59972.1 - 0.0065 16.2 0.0 0.033 13.9 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS59972.1 - 0.13 12.4 0.0 0.13 12.4 0.0 4.9 5 0 0 5 5 5 0 AAA domain RabGAP-TBC PF00566.13 ETS59973.1 - 8.3e-19 67.9 0.0 1.4e-10 41.0 0.0 3.2 3 0 0 3 3 3 3 Rab-GTPase-TBC domain DUF3759 PF12585.3 ETS59974.1 - 2.5e-35 120.2 6.9 2.9e-35 120.0 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF4149 PF13664.1 ETS59975.1 - 0.17 11.9 3.5 0.23 11.5 1.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) PfkB PF00294.19 ETS59976.1 - 4.1e-08 32.7 0.1 0.00084 18.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase WD40 PF00400.27 ETS59978.1 - 4e-66 216.7 18.9 6.3e-11 41.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 ETS59978.1 - 2.1e-27 95.0 4.6 3.6e-27 94.3 3.2 1.4 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 ETS59978.1 - 3.2e-05 22.8 0.9 0.074 11.7 0.1 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 ETS59978.1 - 0.00011 20.5 3.1 0.94 7.5 0.0 3.5 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETS59978.1 - 0.00071 17.9 0.2 0.51 8.5 0.0 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 ETS59978.1 - 0.0014 17.8 0.2 1.1 8.2 0.0 3.7 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Striatin PF08232.7 ETS59978.1 - 0.007 16.6 0.2 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Striatin family PQQ_2 PF13360.1 ETS59978.1 - 0.012 15.0 1.2 0.066 12.6 0.9 2.2 1 1 1 2 2 2 0 PQQ-like domain DUF812 PF05667.6 ETS59978.1 - 0.095 11.1 0.5 0.14 10.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3450 PF11932.3 ETS59978.1 - 0.17 11.1 1.2 0.29 10.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Bystin PF05291.6 ETS59979.1 - 3e-133 443.4 0.0 4.2e-133 442.9 0.0 1.1 1 0 0 1 1 1 1 Bystin GPP34 PF05719.6 ETS59980.1 - 3.6e-72 242.7 0.0 4.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) POP1 PF06978.6 ETS59981.1 - 3.2e-42 144.3 18.0 3.2e-42 144.3 12.5 3.3 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 ETS59981.1 - 3.7e-08 33.0 3.5 1.4e-07 31.2 0.2 3.0 2 1 0 2 2 2 1 POPLD (NUC188) domain SRP40_C PF05022.7 ETS59983.1 - 1e-28 99.6 1.0 2.5e-28 98.3 0.7 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain adh_short PF00106.20 ETS59984.1 - 2.5e-23 82.8 0.3 3.4e-23 82.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS59984.1 - 7.1e-10 38.8 0.4 2.1e-09 37.3 0.3 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS59984.1 - 0.063 11.9 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS59984.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Kelch_4 PF13418.1 ETS59985.1 - 6.5e-43 144.2 13.5 1.3e-07 31.2 0.1 6.9 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 ETS59985.1 - 1.7e-39 133.1 10.8 4.2e-09 36.3 0.1 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 ETS59985.1 - 9.5e-32 108.2 0.3 2.1e-05 23.9 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 ETS59985.1 - 3.9e-29 100.0 4.4 1.2e-05 25.1 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 ETS59985.1 - 1.1e-27 94.6 9.7 1.2e-06 28.0 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 ETS59985.1 - 1.9e-25 87.9 9.3 3.4e-05 23.8 0.0 6.5 4 1 2 6 6 6 5 Kelch motif PQQ_3 PF13570.1 ETS59985.1 - 0.02 15.1 0.3 3.2 8.1 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain Gar1 PF04410.9 ETS59987.1 - 1e-34 119.2 0.1 3.8e-33 114.1 0.0 3.1 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region Unstab_antitox PF09720.5 ETS59987.1 - 0.024 14.3 1.0 0.061 13.0 0.7 1.7 1 0 0 1 1 1 0 Putative addiction module component zf-AN1 PF01428.11 ETS59989.1 - 1.2e-16 60.2 17.2 8.4e-10 38.3 1.7 3.2 3 0 0 3 3 3 2 AN1-like Zinc finger GHL12 PF14882.1 ETS59989.1 - 0.036 14.1 0.2 0.66 10.1 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 12 Rod_cone_degen PF15201.1 ETS59989.1 - 0.099 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Progressive rod-cone degeneration Transp_Tc5_C PF04236.10 ETS59989.1 - 0.1 12.8 15.4 0.13 12.5 1.6 3.3 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Malate_synthase PF01274.17 ETS59990.1 - 1.4e-208 693.1 0.0 1.7e-208 692.8 0.0 1.1 1 0 0 1 1 1 1 Malate synthase Thioredoxin PF00085.15 ETS59990.1 - 2.2e-25 88.3 0.0 4.3e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS59990.1 - 5.7e-06 26.5 0.1 2.6e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS59990.1 - 2.7e-05 24.1 0.0 0.00038 20.5 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 ETS59990.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 ETS59990.1 - 0.0018 17.8 0.1 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 ETS59990.1 - 0.0031 17.2 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Esterase_phd PF10503.4 ETS59990.1 - 0.022 14.0 0.6 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Redoxin PF08534.5 ETS59990.1 - 0.027 14.0 0.1 0.16 11.4 0.1 2.1 1 1 0 1 1 1 0 Redoxin Bromodomain PF00439.20 ETS59990.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain HATPase_c PF02518.21 ETS59991.1 - 2.6e-29 101.1 0.1 1.7e-28 98.5 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS59991.1 - 1.2e-25 89.7 0.1 4.5e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 ETS59991.1 - 1.2e-20 73.5 2.4 5.8e-06 26.2 0.0 4.6 4 0 0 4 4 4 3 PAS fold HisKA PF00512.20 ETS59991.1 - 4.1e-19 68.3 0.1 1.3e-18 66.7 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 ETS59991.1 - 2.1e-14 53.7 0.0 8.2e-08 32.5 0.0 4.6 4 0 0 4 4 4 2 PAS domain PAS_3 PF08447.6 ETS59991.1 - 5e-13 48.9 2.1 5e-13 48.9 1.4 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 ETS59991.1 - 1.7e-12 47.1 0.8 0.0011 18.7 0.0 5.0 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.1 ETS59991.1 - 0.00064 19.4 0.1 3.8 7.5 0.0 3.7 4 0 0 4 4 4 2 PAS domain HATPase_c_3 PF13589.1 ETS59991.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_11 PF14598.1 ETS59991.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain DEAD PF00270.24 ETS59992.1 - 6.6e-39 133.1 0.0 2.8e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.1 ETS59992.1 - 3e-21 74.7 0.0 8.3e-21 73.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 ETS59992.1 - 3.5e-18 65.2 0.0 8.9e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS59992.1 - 5.6e-07 29.5 1.8 6.8e-07 29.3 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETS59992.1 - 0.018 14.7 0.0 0.07 12.8 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 ETS59992.1 - 0.022 14.9 0.1 0.19 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cwf_Cwc_15 PF04889.7 ETS59992.1 - 10 5.7 32.6 2.1 7.9 14.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.14 ETS59993.1 - 2.3e-28 99.7 0.3 6.9e-27 94.9 0.2 2.6 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 ETS59993.1 - 6.7e-08 32.0 5.7 1.1e-07 31.3 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS59993.1 - 1.5e-06 27.8 8.6 2.5e-06 27.1 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 ETS59993.1 - 1.8e-06 27.7 6.4 3e-06 27.0 4.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETS59993.1 - 2.2e-06 27.2 4.6 3.7e-06 26.5 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS59993.1 - 8.4e-06 25.7 7.8 1.4e-05 25.0 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS59993.1 - 0.00014 21.4 5.6 0.00026 20.6 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS59993.1 - 0.0045 16.6 4.1 0.011 15.3 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 ETS59993.1 - 0.0066 16.2 2.6 0.014 15.1 1.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 ETS59993.1 - 0.0076 15.8 2.0 0.015 14.8 1.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Psu PF07455.6 ETS59993.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) zf-rbx1 PF12678.2 ETS59993.1 - 0.41 10.7 5.6 1.3 9.1 3.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger GMC_oxred_N PF00732.14 ETS59994.1 - 1.1e-47 162.6 0.0 1.6e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS59994.1 - 3.6e-40 137.5 0.1 5.7e-40 136.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 ETS59994.1 - 0.00026 20.9 0.1 0.0007 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS59994.1 - 0.00047 19.1 0.1 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS59994.1 - 0.0015 17.4 0.1 0.0027 16.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS59994.1 - 0.0047 16.9 0.1 0.11 12.5 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS59994.1 - 0.0094 14.9 0.1 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 ETS59994.1 - 0.0094 15.0 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 ETS59994.1 - 0.13 10.7 0.2 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein COG5 PF10392.4 ETS59995.1 - 1e-18 67.5 4.9 3.6e-16 59.3 1.9 3.2 2 0 0 2 2 2 2 Golgi transport complex subunit 5 IncA PF04156.9 ETS59995.1 - 0.11 12.0 7.0 0.038 13.5 2.7 1.8 2 0 0 2 2 2 0 IncA protein dCMP_cyt_deam_1 PF00383.17 ETS59996.1 - 7.5e-25 86.5 2.3 1.3e-24 85.7 1.6 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 ETS59996.1 - 0.00011 22.9 0.0 0.00028 21.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS59996.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS59996.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETS59996.1 - 0.023 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS59996.1 - 0.055 13.2 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APOBEC_N PF08210.6 ETS59996.1 - 0.12 11.9 0.8 0.21 11.1 0.5 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain AAA_22 PF13401.1 ETS59996.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TFIIIC_sub6 PF10419.4 ETS59998.1 - 5.9e-09 35.2 0.0 1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit PH_9 PF15410.1 ETS59999.1 - 1.9e-08 34.4 0.1 9.3e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETS59999.1 - 2.1e-07 31.0 0.0 4.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETS59999.1 - 0.013 15.6 0.1 0.12 12.6 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Bestrophin PF01062.16 ETS60000.1 - 3.6e-22 78.6 0.1 2.9e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Peptidase_M16 PF00675.15 ETS60001.1 - 1.4e-44 151.4 1.1 1.4e-41 141.7 0.0 3.6 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 ETS60001.1 - 2e-30 105.8 0.0 2.9e-20 72.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain S1-like PF14444.1 ETS60001.1 - 0.059 13.1 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 S1-like Aa_trans PF01490.13 ETS60002.1 - 6.4e-34 117.1 35.2 7.4e-34 116.9 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2061 PF09834.4 ETS60002.1 - 0.032 14.4 0.5 0.032 14.4 0.3 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) tRNA-synt_1b PF00579.20 ETS60003.1 - 1.1e-73 247.9 0.0 1.4e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FimP PF09766.4 ETS60004.1 - 2.8e-29 102.3 13.7 3.8e-29 101.8 9.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein Ribosomal_L25p PF01386.14 ETS60004.1 - 0.13 12.4 0.9 0.3 11.2 0.0 2.0 2 1 1 3 3 3 0 Ribosomal L25p family BAR_2 PF10455.4 ETS60004.1 - 0.49 9.2 10.7 2.5 6.9 7.4 1.9 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF1640 PF07798.6 ETS60004.1 - 0.67 9.9 11.4 5.9 6.8 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) FlaC_arch PF05377.6 ETS60004.1 - 4.3 7.3 5.8 8.1 6.4 0.2 3.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Afi1 PF07792.7 ETS60005.1 - 2e-40 138.1 0.0 3.5e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 ETS60005.1 - 2.1e-32 111.1 0.0 3.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 ETS60005.1 - 3e-08 32.5 0.0 0.018 13.5 0.0 3.6 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 ETS60005.1 - 0.00037 19.8 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Peptidase_C50 PF03568.12 ETS60006.1 - 3.1e-73 246.6 0.0 1.1e-71 241.5 0.0 2.8 1 1 0 1 1 1 1 Peptidase family C50 TPR_2 PF07719.12 ETS60006.1 - 0.00013 21.6 4.8 8.1 6.6 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS60006.1 - 0.00021 20.8 1.5 0.71 9.8 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS60006.1 - 0.015 15.6 9.9 0.053 13.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS60006.1 - 0.046 13.5 0.9 54 3.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS60006.1 - 0.32 10.6 1.7 75 3.1 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS60006.1 - 0.63 10.6 17.2 0.38 11.3 0.8 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS60006.1 - 1.8 9.4 24.2 0.3 11.8 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat SNF2_N PF00176.18 ETS60007.1 - 1.6e-70 237.2 0.1 2.6e-70 236.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS60007.1 - 3.7e-12 45.9 0.0 7.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS60007.1 - 3.4e-09 36.7 0.1 1.4e-08 34.7 0.0 2.0 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS60007.1 - 5e-09 35.8 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 ETS60007.1 - 4.8e-07 29.3 5.5 4.8e-07 29.3 3.8 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS60007.1 - 1.4e-06 28.1 6.3 1.4e-06 28.1 4.3 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS60007.1 - 6.5e-06 25.7 6.4 6.5e-06 25.7 4.4 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS60007.1 - 4e-05 23.3 8.2 4e-05 23.3 5.7 2.6 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS60007.1 - 0.00014 21.4 6.6 0.00014 21.4 4.6 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS60007.1 - 0.0086 15.7 1.1 0.025 14.2 0.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 ETS60007.1 - 0.043 13.6 2.6 0.1 12.3 1.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 ETS60007.1 - 0.055 12.9 13.0 0.081 12.4 1.0 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Ald_Xan_dh_C2 PF02738.13 ETS60008.1 - 1.3e-184 614.5 0.0 1.7e-184 614.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 ETS60008.1 - 5.5e-38 130.0 0.0 1.5e-37 128.6 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 ETS60008.1 - 4.1e-35 120.2 0.0 7.8e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 ETS60008.1 - 1.6e-25 89.0 0.0 3.7e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 ETS60008.1 - 3.8e-25 87.5 0.1 1.3e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.22 ETS60008.1 - 2e-06 27.4 0.0 5.6e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Velvet PF11754.3 ETS60009.1 - 2e-24 86.3 0.7 5.4e-24 84.9 0.5 1.7 1 1 0 1 1 1 1 Velvet factor Med8 PF10232.4 ETS60010.1 - 3 7.2 6.7 25 4.2 4.5 2.4 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Lgl_C PF08596.5 ETS60011.1 - 1.1e-23 83.4 0.0 6.8e-19 67.6 0.0 2.6 2 1 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 ETS60011.1 - 0.00096 18.9 0.9 0.0098 15.7 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF3312 PF11768.3 ETS60011.1 - 0.65 8.1 0.0 5.2 5.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Glyco_transf_20 PF00982.16 ETS60012.1 - 2e-152 507.9 0.0 3.3e-152 507.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 ETS60012.1 - 2.1e-68 229.7 0.0 4.7e-68 228.6 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase ING PF12998.2 ETS60013.1 - 2.5e-14 53.4 0.0 9.5e-14 51.5 0.0 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 ETS60013.1 - 2.1e-07 30.5 8.9 3.7e-07 29.7 6.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS60013.1 - 0.014 14.7 1.7 0.025 13.8 1.2 1.4 1 0 0 1 1 1 0 PHD-finger DUF4449 PF14613.1 ETS60013.1 - 0.019 14.9 0.9 0.043 13.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) zf-RING-like PF08746.6 ETS60013.1 - 0.7 9.9 6.7 1.3 9.0 4.6 1.5 1 0 0 1 1 1 0 RING-like domain SMC_N PF02463.14 ETS60014.1 - 4.5e-64 215.6 0.0 2.5e-63 213.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETS60014.1 - 1.7e-30 105.4 0.2 7.3e-30 103.4 0.1 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETS60014.1 - 3.8e-13 50.0 5.0 3.1e-08 33.9 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.1 ETS60014.1 - 1.8e-08 33.8 0.0 4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 ETS60014.1 - 6.9e-07 28.6 3.2 6.8e-05 22.0 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain Reo_sigmaC PF04582.7 ETS60014.1 - 4.3e-06 26.1 16.7 0.0048 16.1 0.4 5.1 5 0 0 5 5 5 2 Reovirus sigma C capsid protein IncA PF04156.9 ETS60014.1 - 7.1e-05 22.4 6.5 7.1e-05 22.4 4.5 7.4 5 2 1 6 6 5 2 IncA protein SbcCD_C PF13558.1 ETS60014.1 - 0.0012 18.6 0.0 0.0045 16.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit WEMBL PF05701.6 ETS60014.1 - 0.0024 16.4 1.0 0.0024 16.4 0.7 5.4 4 1 1 5 5 5 2 Weak chloroplast movement under blue light ABC_tran PF00005.22 ETS60014.1 - 0.07 13.4 0.0 0.07 13.4 0.0 5.6 5 2 1 6 6 5 0 ABC transporter AAA_23 PF13476.1 ETS60014.1 - 0.083 13.2 83.8 0.051 13.9 34.6 5.7 3 2 1 4 4 4 0 AAA domain NPV_P10 PF05531.7 ETS60014.1 - 0.27 11.4 22.7 17 5.7 0.2 6.7 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Amidase PF01425.16 ETS60014.1 - 0.45 9.2 5.3 1.7 7.4 3.7 2.0 1 0 0 1 1 1 0 Amidase AAA_13 PF13166.1 ETS60014.1 - 2.2 6.6 69.9 0.048 12.1 15.5 6.2 4 2 1 5 5 4 0 AAA domain DUF3584 PF12128.3 ETS60014.1 - 3.3 4.9 97.8 1.1 6.5 36.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF3584) KH_1 PF00013.24 ETS60016.1 - 6.4e-06 25.7 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 ETS60016.1 - 7.7e-05 22.2 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 ETS60016.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 KH domain DUF3720 PF12517.3 ETS60016.1 - 4.2 8.1 18.7 0.32 11.7 9.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) GRAB PF10375.4 ETS60017.1 - 9.4e-07 28.2 4.5 1.5e-06 27.5 0.3 2.4 2 0 0 2 2 2 1 GRIP-related Arf-binding domain SlyX PF04102.7 ETS60017.1 - 0.036 14.4 1.3 0.036 14.4 0.9 4.7 3 1 2 5 5 5 0 SlyX bZIP_1 PF00170.16 ETS60017.1 - 0.073 13.0 0.5 0.073 13.0 0.4 4.0 4 0 0 4 4 4 0 bZIP transcription factor TBPIP PF07106.8 ETS60017.1 - 0.31 10.5 17.7 0.24 10.9 2.5 3.4 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IFT57 PF10498.4 ETS60017.1 - 0.9 8.2 16.7 1.5 7.4 3.9 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF904 PF06005.7 ETS60017.1 - 1.2 9.4 0.0 1.2 9.4 0.0 4.6 3 2 0 3 3 3 0 Protein of unknown function (DUF904) DUF972 PF06156.8 ETS60017.1 - 5.7 7.3 16.6 0.16 12.3 1.3 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Atg14 PF10186.4 ETS60017.1 - 8.8 5.1 30.9 0.46 9.3 10.6 2.7 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TPP_enzyme_N PF02776.13 ETS60018.1 - 5.4e-54 182.2 0.0 5.4e-54 182.2 0.0 3.2 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 ETS60018.1 - 1.7e-48 164.0 0.1 6.5e-47 158.9 0.0 2.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETS60018.1 - 2.6e-37 127.6 0.3 2e-36 124.7 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Med3 PF11593.3 ETS60018.1 - 0.054 12.7 5.6 0.082 12.1 3.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dor1 PF04124.7 ETS60019.1 - 3.9e-20 71.5 2.6 3.1e-16 58.7 0.7 3.1 2 1 0 2 2 2 2 Dor1-like family Ribosomal_S10 PF00338.17 ETS60020.1 - 2.2e-32 110.7 0.5 2.7e-32 110.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribophorin_II PF05817.9 ETS60021.1 - 7.5e-06 24.4 0.3 0.00013 20.3 0.2 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II BTB PF00651.26 ETS60022.1 - 2.5e-13 49.9 0.0 2.8e-10 40.1 0.0 3.5 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.20 ETS60022.1 - 1.9e-09 37.0 0.0 3.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Pkinase PF00069.20 ETS60023.1 - 3.6e-68 229.5 0.0 4.9e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60023.1 - 1.6e-41 142.1 0.0 2.4e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 ETS60023.1 - 1.8e-30 104.7 0.0 2.8e-15 56.0 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 ETS60023.1 - 3.4e-07 29.4 0.0 1.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 ETS60023.1 - 0.0021 17.5 0.0 0.67 9.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) Kdo PF06293.9 ETS60023.1 - 0.09 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BBS2_Mid PF14783.1 ETS60023.1 - 0.14 11.8 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Aldo_ket_red PF00248.16 ETS60024.1 - 1.3e-41 142.2 0.0 1.6e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.17 ETS60025.1 - 2.9e-17 62.0 0.0 5.7e-17 61.1 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60025.1 - 1.4e-14 53.7 0.0 2.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60025.1 - 2.7e-08 33.5 0.0 5.4e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS60025.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif OppC_N PF12911.2 ETS60027.1 - 0.13 11.6 0.6 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C adh_short PF00106.20 ETS60031.1 - 6e-15 55.5 1.3 1.8e-14 54.0 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS60031.1 - 5.3e-05 23.1 0.0 8.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS60031.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS60031.1 - 0.28 10.8 8.7 0.031 13.9 1.2 2.6 2 1 0 2 2 2 0 KR domain DAO PF01266.19 ETS60034.1 - 5.3e-44 150.5 3.7 8e-44 149.9 2.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS60034.1 - 1.8e-05 24.5 0.4 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS60034.1 - 0.0024 17.9 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS60034.1 - 0.0037 17.2 0.5 0.013 15.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS60034.1 - 0.013 14.4 0.1 0.1 11.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS60034.1 - 0.019 14.8 0.2 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS60034.1 - 0.03 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ECH PF00378.15 ETS60035.1 - 7.5e-25 87.4 0.3 9.9e-25 87.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Lumazine_bd PF12870.2 ETS60035.1 - 0.066 13.2 0.4 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Lumazine-binding domain Ctr PF04145.10 ETS60036.1 - 4.6e-31 107.7 2.1 8e-31 107.0 0.1 1.9 2 0 0 2 2 2 1 Ctr copper transporter family RSN1_TM PF13967.1 ETS60036.1 - 0.073 12.6 0.6 0.14 11.7 0.4 1.4 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF1049 PF06305.6 ETS60036.1 - 0.093 12.2 2.1 1.3 8.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Bromodomain PF00439.20 ETS60037.1 - 7.8e-36 121.8 0.9 2.9e-18 65.5 0.0 2.5 2 0 0 2 2 2 2 Bromodomain HlyD_2 PF12700.2 ETS60037.1 - 0.79 8.8 10.8 1.5 7.9 7.5 1.4 1 0 0 1 1 1 0 HlyD family secretion protein LMBR1 PF04791.11 ETS60037.1 - 2.6 6.5 4.1 4.1 5.8 2.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.14 ETS60037.1 - 5.7 4.6 14.5 8.1 4.1 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SCAMP PF04144.8 ETS60038.1 - 1.8e-50 171.2 4.0 2.2e-50 171.0 2.8 1.0 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.3 ETS60038.1 - 0.019 14.1 1.0 0.029 13.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1700 PF08006.6 ETS60038.1 - 0.5 9.6 2.7 0.9 8.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Septin PF00735.13 ETS60039.1 - 5.1e-113 376.7 1.4 6.3e-113 376.4 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 ETS60039.1 - 2.7e-08 33.7 0.1 1.3e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETS60039.1 - 2.8e-06 26.6 0.0 5.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 ETS60039.1 - 2e-05 24.5 0.4 0.052 13.3 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 ETS60039.1 - 2.4e-05 23.5 0.4 6.1e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 ETS60039.1 - 0.00015 21.3 0.4 0.0017 17.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 ETS60039.1 - 0.00025 20.5 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 ETS60039.1 - 0.00063 19.2 0.1 0.0012 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 ETS60039.1 - 0.0014 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IIGP PF05049.8 ETS60039.1 - 0.0014 17.5 0.0 0.0032 16.3 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 ETS60039.1 - 0.0016 18.7 0.3 0.0053 17.0 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETS60039.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 ETS60039.1 - 0.0078 16.7 0.1 0.026 15.0 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 ETS60039.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 ETS60039.1 - 0.018 13.9 0.2 0.032 13.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.7 ETS60039.1 - 0.02 14.0 0.1 0.075 12.1 0.1 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 ETS60039.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS60039.1 - 0.023 14.8 0.1 0.052 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS60039.1 - 0.028 15.2 1.1 3.2 8.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS60039.1 - 0.029 14.6 0.6 0.13 12.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS60039.1 - 0.04 13.8 1.0 0.51 10.2 0.0 2.8 3 1 0 3 3 2 0 AAA domain MobB PF03205.9 ETS60039.1 - 0.05 13.3 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 ETS60039.1 - 0.059 13.6 0.3 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 ETS60039.1 - 0.069 12.5 0.1 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 Ras family DUF87 PF01935.12 ETS60039.1 - 0.075 12.8 0.5 0.64 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 FAT PF02259.18 ETS60040.1 - 7.6e-125 416.5 2.9 7.6e-125 416.5 2.0 2.5 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 ETS60040.1 - 4e-56 190.1 0.1 7.2e-56 189.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 ETS60040.1 - 3.6e-52 176.5 0.1 4.6e-51 172.9 0.0 3.1 3 1 1 4 4 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 ETS60040.1 - 1.1e-40 137.7 0.2 1.1e-40 137.7 0.1 3.1 3 1 1 4 4 3 1 Rapamycin binding domain HEAT_2 PF13646.1 ETS60040.1 - 2.6e-20 72.5 15.8 0.0006 20.0 0.0 12.1 8 2 5 13 13 12 5 HEAT repeats FATC PF02260.15 ETS60040.1 - 1.7e-12 46.5 0.1 3.8e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 ETS60040.1 - 2.3e-11 42.7 11.0 0.51 10.5 0.1 11.1 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.1 ETS60040.1 - 6.5e-06 26.4 21.8 2.6 8.6 0.1 12.4 12 2 3 15 15 12 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETS60040.1 - 1.9e-05 24.9 0.1 15 6.0 0.0 6.0 6 1 0 6 6 4 0 Vacuolar 14 Fab1-binding region TPR_19 PF14559.1 ETS60040.1 - 0.00064 20.0 0.2 12 6.3 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat VHS PF00790.14 ETS60040.1 - 0.019 14.5 0.1 0.98 9.0 0.0 3.5 4 0 0 4 4 3 0 VHS domain TPR_11 PF13414.1 ETS60040.1 - 0.021 14.4 8.7 5.7 6.6 0.0 5.5 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.23 ETS60040.1 - 0.025 14.1 0.7 17 5.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnd1 PF12717.2 ETS60040.1 - 0.039 13.7 2.0 2 8.2 0.1 4.4 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 TSA PF03249.8 ETS60040.1 - 0.064 11.7 0.3 0.14 10.7 0.2 1.4 1 0 0 1 1 1 0 Type specific antigen TPR_7 PF13176.1 ETS60040.1 - 0.11 12.3 1.7 36 4.4 0.0 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.15 ETS60040.1 - 0.2 9.9 6.7 2.9 6.0 0.1 3.9 3 1 1 4 4 4 0 Adaptin N terminal region Sporozoite_P67 PF05642.6 ETS60040.1 - 2.6 5.8 0.1 3.9 5.2 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_2 PF07719.12 ETS60040.1 - 2.6 8.1 10.8 4.1 7.5 0.2 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat LSM PF01423.17 ETS60041.1 - 2.6e-06 26.8 0.0 8.9e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 LSM domain Sel1 PF08238.7 ETS60042.1 - 2e-36 123.6 33.3 3.9e-06 27.3 0.5 7.8 7 0 0 7 7 7 7 Sel1 repeat DPBB_1 PF03330.13 ETS60043.1 - 7.3e-11 41.9 0.2 1.2e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 ETS60043.1 - 0.06 13.0 0.6 0.091 12.4 0.1 1.5 1 1 0 1 1 1 0 Barwin family Toxin_1 PF00087.16 ETS60043.1 - 0.15 12.4 0.6 0.28 11.5 0.4 1.5 1 1 1 2 2 2 0 Snake toxin AhpC-TSA PF00578.16 ETS60045.1 - 1.1e-24 86.5 0.0 1.5e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS60045.1 - 1.5e-12 47.3 0.0 3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 ETS60045.1 - 0.048 13.5 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme CKS PF01111.14 ETS60046.1 - 2.3e-30 104.2 0.2 3.1e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Sec23_trunk PF04811.10 ETS60047.1 - 1.3e-74 250.6 0.0 2.1e-74 249.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETS60047.1 - 1.1e-22 79.3 0.3 2.7e-22 78.1 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 ETS60047.1 - 3.2e-16 58.6 8.9 6.1e-16 57.7 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 ETS60047.1 - 4.2e-16 59.2 0.0 1.2e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 ETS60047.1 - 3.9e-08 32.8 0.0 8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat PWI PF01480.12 ETS60048.1 - 1.2e-08 34.8 0.1 2.5e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 ETS60048.1 - 2e-05 24.1 0.0 4.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60048.1 - 0.092 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mpv17_PMP22 PF04117.7 ETS60049.1 - 1.6e-24 85.2 1.0 3.4e-24 84.2 0.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family TFIIF_alpha PF05793.7 ETS60051.1 - 9.6e-09 34.1 60.2 0.00041 18.8 4.9 3.6 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BRCA-2_OB1 PF09103.5 ETS60054.1 - 1e-31 109.0 0.0 2.2e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.13 ETS60054.1 - 2e-07 30.1 0.1 3.7e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 BRCA2 repeat BRCA-2_helical PF09169.5 ETS60054.1 - 4.4e-06 26.3 2.2 1.1e-05 25.0 1.1 2.0 3 0 0 3 3 3 1 BRCA2, helical SIS PF01380.17 ETS60055.1 - 3.1e-59 198.2 0.1 6.8e-33 113.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 ETS60055.1 - 4.4e-28 98.0 0.0 8.1e-19 67.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 ETS60055.1 - 1.5e-18 67.0 0.0 3.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 ETS60055.1 - 9.5e-13 47.9 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 ETS60055.1 - 3.7e-07 29.0 0.0 5.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 ETS60055.1 - 0.01 15.5 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 SIS domain Plasmid_Txe PF06769.8 ETS60055.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded toxin Txe 2-oxoacid_dh PF00198.18 ETS60056.1 - 8.7e-65 218.2 0.0 2.1e-64 216.9 0.0 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 ETS60056.1 - 5.6e-19 67.5 0.1 1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 ETS60056.1 - 1.1e-17 63.3 2.9 1.7e-16 59.5 0.1 3.0 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 ETS60056.1 - 0.051 13.2 0.0 1.2 8.9 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like Helicase_C_2 PF13307.1 ETS60057.1 - 2e-53 180.7 0.0 5.1e-53 179.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 ETS60057.1 - 3.3e-44 150.3 0.0 4.9e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 NUDIX-like PF09296.6 ETS60057.1 - 0.056 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain ResIII PF04851.10 ETS60057.1 - 0.071 12.9 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TPT PF03151.11 ETS60058.1 - 6e-24 84.4 12.1 6e-24 84.4 8.4 2.2 3 0 0 3 3 3 1 Triose-phosphate Transporter family Sec61_beta PF03911.11 ETS60058.1 - 0.093 12.5 4.5 5 7.0 0.3 3.6 3 0 0 3 3 3 0 Sec61beta family PXA PF02194.10 ETS60059.1 - 1.6e-35 122.3 0.0 6.1e-35 120.4 0.0 2.0 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 ETS60059.1 - 1e-27 96.4 0.4 3.6e-27 94.7 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 ETS60059.1 - 6.5e-14 51.6 0.0 2.1e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 PX domain RGS PF00615.14 ETS60059.1 - 2.4e-06 27.6 0.0 8.8e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF342 PF03961.8 ETS60059.1 - 0.062 11.7 0.1 0.11 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Snf7 PF03357.16 ETS60059.1 - 0.67 9.3 4.5 0.34 10.2 1.1 2.0 2 0 0 2 2 2 0 Snf7 Mog1 PF04603.7 ETS60061.1 - 5.9e-29 100.8 0.0 7.5e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Sterol_MT_C PF08498.5 ETS60062.1 - 1.7e-29 101.5 0.7 2.5e-29 100.9 0.5 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 ETS60062.1 - 2e-20 72.8 0.0 2.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60062.1 - 1.8e-18 66.8 0.0 3.1e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS60062.1 - 7e-16 58.1 0.0 9.5e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 ETS60062.1 - 2.7e-15 56.4 0.0 3.9e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS60062.1 - 9.9e-14 51.8 0.0 6e-13 49.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS60062.1 - 1.8e-13 50.8 0.0 3.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS60062.1 - 1.4e-11 44.6 0.0 2.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS60062.1 - 1.9e-11 43.9 0.0 8.4e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS60062.1 - 2.5e-08 33.3 0.0 4.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 ETS60062.1 - 5.8e-06 25.4 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 ETS60062.1 - 2.2e-05 23.9 0.0 5.4e-05 22.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 ETS60062.1 - 2.7e-05 23.7 0.1 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 ETS60062.1 - 5.6e-05 22.7 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 ETS60062.1 - 0.00054 19.5 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 ETS60062.1 - 0.0011 19.8 0.0 0.013 16.2 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain MetW PF07021.7 ETS60062.1 - 0.0037 16.6 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 ETS60062.1 - 0.0043 16.7 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 ETS60062.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 ETS60062.1 - 0.022 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 ETS60062.1 - 0.025 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 ETS60062.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase N2227 PF07942.7 ETS60062.1 - 0.15 11.0 0.1 5.5 5.8 0.0 2.2 1 1 1 2 2 2 0 N2227-like protein DHFR_1 PF00186.14 ETS60063.1 - 3.6e-29 101.4 0.0 1.3e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase TPR_12 PF13424.1 ETS60064.1 - 2.3e-07 30.6 3.0 7.6e-07 28.9 2.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS60064.1 - 0.014 15.2 0.4 0.064 13.2 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS60064.1 - 0.042 14.4 3.8 0.047 14.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS60064.1 - 0.049 13.5 0.2 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS60064.1 - 0.057 13.2 0.1 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS60064.1 - 0.41 10.5 2.1 0.9 9.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_5 PF00266.14 ETS60065.1 - 1.6e-28 99.5 0.0 2.5e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ABC2_membrane PF01061.19 ETS60066.1 - 2.1e-30 105.5 19.0 3.6e-30 104.7 13.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 ETS60066.1 - 8.6e-26 90.8 0.0 1.3e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS60066.1 - 3.4e-08 33.7 0.0 0.0028 17.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS60066.1 - 3.1e-05 23.4 1.3 0.0052 16.1 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS60066.1 - 9.5e-05 21.8 0.2 0.00033 20.1 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS60066.1 - 0.00014 21.8 0.3 0.00028 20.9 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain DUF258 PF03193.11 ETS60066.1 - 0.00018 20.7 0.1 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS60066.1 - 0.0063 16.6 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS60066.1 - 0.023 15.5 0.0 0.074 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 ETS60066.1 - 0.054 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 ETS60066.1 - 0.07 12.5 0.1 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 ETS60066.1 - 0.074 12.9 0.2 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETS60066.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 ETS60066.1 - 0.088 12.7 0.3 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETS60066.1 - 0.13 12.6 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 ETS60066.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 ETS60066.1 - 0.25 11.6 0.1 0.41 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 ETS60066.1 - 0.29 10.1 0.0 20 4.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 ETS60066.1 - 4.3 6.2 21.1 0.21 10.5 10.6 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Adaptin_N PF01602.15 ETS60067.1 - 7.7e-99 331.3 0.0 6.2e-98 328.4 0.0 2.2 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETS60067.1 - 7.7e-08 32.3 0.1 0.00095 19.0 0.0 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETS60067.1 - 1.8e-07 31.3 10.8 0.0063 16.7 0.1 5.0 3 3 4 7 7 7 5 HEAT repeats HEAT PF02985.17 ETS60067.1 - 1.4e-05 24.7 2.0 6.3 7.1 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat BLVR PF06375.6 ETS60067.1 - 6.4e-05 22.8 1.3 6.4e-05 22.8 0.9 1.6 2 0 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) TIP120 PF08623.5 ETS60067.1 - 0.014 14.9 2.8 0.14 11.6 0.1 3.0 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Tim54 PF11711.3 ETS60068.1 - 1.2e-58 198.5 0.1 1.2e-58 198.5 0.0 3.2 2 1 0 3 3 3 1 Inner membrane protein import complex subunit Tim54 RNase_PH PF01138.16 ETS60069.1 - 5e-25 88.3 0.0 1e-24 87.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Adap_comp_sub PF00928.16 ETS60070.1 - 2.1e-85 286.0 0.1 3.3e-85 285.3 0.0 1.3 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETS60070.1 - 0.00061 19.5 0.6 0.0012 18.6 0.4 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Redoxin PF08534.5 ETS60071.1 - 3.7e-10 39.5 0.0 4.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ETS60071.1 - 2.4e-06 27.2 0.0 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family DUF899 PF05988.7 ETS60071.1 - 0.018 14.5 0.0 0.028 13.8 0.0 1.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF899) LSM PF01423.17 ETS60072.1 - 1.8e-16 59.3 1.0 2.3e-16 59.0 0.7 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 ETS60072.1 - 0.028 14.1 0.1 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) XPG_I PF00867.13 ETS60073.1 - 2.9e-25 88.1 0.0 5.6e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 ETS60073.1 - 2e-23 82.5 0.0 4.1e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 ETS60073.1 - 0.0002 20.9 0.0 0.00045 19.7 0.0 1.6 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 ETS60073.1 - 0.0045 17.1 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_11 PF13414.1 ETS60073.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 ETS60073.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.7 ETS60074.1 - 1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 DUF2292 PF10055.4 ETS60074.1 - 0.12 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) Pmp3 PF01679.12 ETS60075.1 - 5.8e-15 54.7 5.6 9.1e-15 54.1 3.9 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Guanylate_cyc_2 PF09778.4 ETS60076.1 - 0.041 13.0 0.2 0.07 12.3 0.1 1.3 1 1 0 1 1 1 0 Guanylylate cyclase zf-C2H2_4 PF13894.1 ETS60076.1 - 0.8 10.1 5.1 1.5 9.2 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger ERCC4 PF02732.10 ETS60077.1 - 2.6e-27 95.3 0.0 8.5e-27 93.6 0.0 2.0 1 0 0 1 1 1 1 ERCC4 domain ATP-synt_ab PF00006.20 ETS60078.1 - 2.4e-61 206.9 0.0 4.5e-61 206.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 ETS60078.1 - 5.3e-24 84.2 4.3 5.3e-24 84.2 3.0 2.0 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 ETS60078.1 - 1.6e-23 83.3 0.1 2.6e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Arch_ATPase PF01637.13 ETS60078.1 - 0.0078 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase KaiC PF06745.8 ETS60078.1 - 0.0092 15.1 0.2 0.018 14.1 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 ETS60078.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 ETS60078.1 - 0.036 13.7 0.3 2.3 7.9 0.1 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETS60078.1 - 0.058 13.6 0.0 0.74 10.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETS60078.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 ETS60078.1 - 0.08 12.1 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS60078.1 - 0.082 13.0 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS60078.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 ETS60078.1 - 0.18 10.6 0.9 0.56 9.0 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain SpoIIIAH PF12685.2 ETS60079.1 - 0.5 9.8 8.1 12 5.3 5.6 2.3 1 1 0 1 1 1 0 SpoIIIAH-like protein Cyclin_N PF00134.18 ETS60080.1 - 2.1e-09 37.0 0.0 1.2e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain DnaJ PF00226.26 ETS60081.1 - 2.1e-16 59.3 0.1 7.8e-16 57.5 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain DUF2450 PF10475.4 ETS60081.1 - 0.024 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Cyclin_N PF00134.18 ETS60082.1 - 1.8e-13 50.1 0.0 3.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 ETS60082.1 - 3.8e-06 26.6 0.6 1e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 ETS60082.1 - 0.00048 20.0 0.2 0.64 9.9 0.1 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain UAA PF08449.6 ETS60083.1 - 4.9e-70 235.8 3.7 2e-69 233.8 2.5 1.7 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 ETS60083.1 - 6.9e-10 38.7 15.8 1.5e-08 34.4 4.3 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 ETS60083.1 - 3.5e-09 36.7 23.7 1.2e-08 35.0 3.3 4.2 4 1 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 ETS60083.1 - 2.1e-05 24.6 1.8 2.1e-05 24.6 1.2 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 ETS60083.1 - 0.0024 17.0 5.1 0.091 11.8 0.1 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter OppC_N PF12911.2 ETS60083.1 - 0.095 12.0 1.7 0.16 11.3 0.3 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C UPF0546 PF10639.4 ETS60083.1 - 0.34 10.7 5.4 3.1 7.6 0.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 PhyH PF05721.8 ETS60084.1 - 1e-05 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Lysine_decarbox PF03641.9 ETS60085.1 - 7.5e-32 109.9 0.1 1.5e-31 108.9 0.1 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase ABC_tran PF00005.22 ETS60085.1 - 1.6e-14 54.3 0.0 3.8e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS60085.1 - 1.4e-09 38.3 0.2 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 ETS60085.1 - 4.7e-05 22.6 0.0 0.064 12.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 ETS60085.1 - 0.00061 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 ETS60085.1 - 0.0041 16.5 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS60085.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 ETS60085.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 ETS60085.1 - 0.044 13.0 0.0 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 ETS60085.1 - 0.06 14.1 0.3 0.13 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS60085.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 ETS60085.1 - 0.076 12.4 0.0 1.7 8.0 0.0 2.4 2 1 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 ETS60085.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 ETS60085.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 ETS60085.1 - 0.14 11.4 0.1 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF4255 PF14065.1 ETS60085.1 - 0.18 11.2 0.1 0.38 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) AAA_23 PF13476.1 ETS60085.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Med19 PF10278.4 ETS60085.1 - 0.24 11.0 0.0 0.5 10.0 0.0 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 L51_S25_CI-B8 PF05047.11 ETS60087.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ECH PF00378.15 ETS60088.1 - 1.3e-39 135.7 0.0 1.8e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CBFD_NFYB_HMF PF00808.18 ETS60089.1 - 1.2e-18 66.8 0.1 1.2e-18 66.8 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS60089.1 - 0.0099 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DAHP_synth_1 PF00793.15 ETS60090.1 - 7.4e-93 310.1 0.0 8.8e-93 309.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SRX PF09201.5 ETS60090.1 - 0.031 13.9 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 SRX zf-RING_2 PF13639.1 ETS60091.1 - 2.4e-13 49.6 5.9 4.2e-13 48.9 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS60091.1 - 4.2e-09 35.9 6.0 7e-09 35.2 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS60091.1 - 1.1e-07 31.7 6.0 1.7e-07 31.1 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS60091.1 - 3.2e-07 29.9 6.3 5.1e-07 29.3 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETS60091.1 - 4.6e-07 29.8 4.2 8.9e-07 28.9 2.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS60091.1 - 0.00021 20.8 7.1 0.00035 20.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS60091.1 - 0.0003 20.4 5.1 0.00064 19.3 3.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETS60091.1 - 0.11 12.2 2.5 0.22 11.3 1.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 ETS60091.1 - 0.37 10.4 4.7 0.66 9.6 3.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Peroxin-13_N PF04088.8 ETS60092.1 - 1.3e-53 181.2 0.1 2.7e-53 180.1 0.1 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 ETS60092.1 - 6.9e-13 47.9 0.1 2.5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 ETS60092.1 - 1.3e-12 46.8 0.0 2.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS60092.1 - 2.3e-11 43.0 0.0 3.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.9 ETS60092.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region WD40 PF00400.27 ETS60093.1 - 3.1e-72 236.0 19.6 1e-12 47.4 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETS60093.1 - 1.3e-13 49.9 9.2 8.7e-05 20.8 0.0 5.6 1 1 4 6 6 6 6 Nucleoporin Nup120/160 LisH PF08513.6 ETS60093.1 - 0.0054 16.4 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 LisH IF-2B PF01008.12 ETS60094.1 - 1.8e-57 194.5 0.0 2.2e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DEAD PF00270.24 ETS60095.1 - 5.3e-47 159.4 0.0 3.9e-45 153.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS60095.1 - 4.1e-25 87.4 0.0 9.9e-25 86.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 ETS60095.1 - 0.0075 14.7 0.4 1.6 7.0 0.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF1253) Aminotran_3 PF00202.16 ETS60096.1 - 2.6e-109 365.1 0.0 3.9e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ETS60096.1 - 0.00085 18.3 0.0 0.0018 17.3 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS60096.1 - 0.013 14.6 0.0 0.068 12.2 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase DUF2007 PF09413.5 ETS60096.1 - 0.11 12.3 0.1 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) DUF3128 PF11326.3 ETS60097.1 - 2.9e-24 84.9 0.6 4e-24 84.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) tRNA-synt_2b PF00587.20 ETS60099.1 - 9.5e-68 227.1 0.1 1.4e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS60099.1 - 6e-21 74.1 0.1 2.3e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain zf-H2C2_2 PF13465.1 ETS60100.1 - 4e-19 67.8 19.7 3.8e-08 33.2 0.1 5.2 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETS60100.1 - 4.1e-19 67.6 29.5 0.00011 22.3 1.1 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS60100.1 - 4e-09 36.1 25.5 0.013 15.8 0.5 5.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS60100.1 - 0.0024 17.9 2.1 0.62 10.2 0.0 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding IGPD PF00475.13 ETS60100.1 - 0.04 13.7 0.5 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase zf-C2H2_6 PF13912.1 ETS60100.1 - 0.98 9.4 8.7 1.4 8.8 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger NUDIX PF00293.23 ETS60101.1 - 2.9e-18 65.8 0.0 7.7e-18 64.4 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain LAT PF15234.1 ETS60101.1 - 0.029 13.8 0.4 0.068 12.6 0.0 1.7 2 0 0 2 2 2 0 Linker for activation of T-cells Hamartin PF04388.7 ETS60101.1 - 0.16 10.6 1.3 0.21 10.1 0.9 1.1 1 0 0 1 1 1 0 Hamartin protein ATP-synt_10 PF05176.9 ETS60102.1 - 1.1e-57 195.2 0.0 1.7e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein GFO_IDH_MocA PF01408.17 ETS60103.1 - 1.4e-24 86.8 1.1 2.7e-24 85.9 0.8 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 ETS60103.1 - 0.0003 21.0 0.4 0.00061 20.0 0.3 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 ETS60103.1 - 0.00041 20.7 1.9 0.00068 20.0 1.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ETS60103.1 - 0.011 16.1 0.1 0.029 14.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 ETS60103.1 - 0.035 13.8 1.2 0.06 13.0 0.8 1.4 1 0 0 1 1 1 0 Rossmann-like domain Redoxin PF08534.5 ETS60104.1 - 1.9e-30 105.3 0.1 2.3e-30 105.0 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ETS60104.1 - 2.5e-14 53.0 0.0 4e-14 52.3 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Fip1 PF05182.8 ETS60105.1 - 2.4e-19 68.3 2.9 2.5e-19 68.2 0.7 2.0 2 0 0 2 2 2 1 Fip1 motif PAS_9 PF13426.1 ETS60106.1 - 4.6e-27 94.4 0.0 7.3e-16 58.4 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 ETS60106.1 - 5.1e-16 58.4 0.0 3.7e-10 39.5 0.0 4.1 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.6 ETS60106.1 - 1.3e-14 54.0 0.0 4.9e-07 29.7 0.0 3.8 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.5 ETS60106.1 - 1.2e-07 31.7 0.0 0.00015 21.7 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 ETS60106.1 - 4.1e-06 26.4 0.0 0.0067 16.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 ETS60106.1 - 0.00034 20.5 0.0 0.0044 16.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain DUF3198 PF11433.3 ETS60106.1 - 0.29 11.0 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) SMC_N PF02463.14 ETS60109.1 - 3.5e-74 248.7 1.0 2.4e-73 246.0 0.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETS60109.1 - 4.7e-25 87.8 0.0 1.9e-24 85.9 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETS60109.1 - 1.2e-14 54.9 0.5 2.5e-06 27.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETS60109.1 - 5.6e-12 46.4 1.9 5.6e-12 46.4 1.3 6.7 3 3 1 4 4 4 1 AAA domain Reo_sigmaC PF04582.7 ETS60109.1 - 3e-05 23.3 26.7 0.0019 17.4 0.3 4.8 3 2 2 5 5 5 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 ETS60109.1 - 0.0005 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF812 PF05667.6 ETS60109.1 - 0.00071 18.2 23.1 0.00071 18.2 16.0 4.6 4 1 1 5 5 5 1 Protein of unknown function (DUF812) DivIVA PF05103.8 ETS60109.1 - 0.0021 18.0 5.8 0.0021 18.0 4.0 9.0 5 2 5 10 10 10 2 DivIVA protein Pkinase PF00069.20 ETS60111.1 - 6e-61 205.8 0.0 3.2e-59 200.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60111.1 - 5.8e-29 100.9 0.0 5.9e-28 97.6 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60111.1 - 3.9e-05 22.7 0.0 6.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HSP90 PF00183.13 ETS60113.1 - 8.7e-250 829.6 29.7 1e-249 829.3 20.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 ETS60113.1 - 3e-12 46.2 0.0 7e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETS60113.1 - 1.7e-11 43.8 0.3 1.7e-11 43.8 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 ETS60113.1 - 5.8 6.2 22.6 0.2 11.0 10.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Cellulase PF00150.13 ETS60114.1 - 0.00032 20.0 0.0 0.00046 19.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.8 ETS60115.1 - 1.8e-36 125.7 0.0 2.7e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS60115.1 - 3.5e-09 36.5 0.1 5.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS60115.1 - 5.6e-08 32.2 0.0 2.5e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS60115.1 - 3.2e-06 27.1 2.1 3.2e-06 27.1 1.4 2.3 1 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS60115.1 - 0.00089 18.7 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 ETS60115.1 - 0.0032 15.9 0.0 0.0062 15.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Thioesterase PF00975.15 ETS60115.1 - 0.0033 17.6 0.5 0.0081 16.4 0.0 1.9 3 0 0 3 3 3 1 Thioesterase domain DLH PF01738.13 ETS60115.1 - 0.005 16.1 0.0 0.076 12.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETS60115.1 - 0.011 15.2 0.1 0.023 14.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 ETS60115.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 ETS60115.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) adh_short PF00106.20 ETS60117.1 - 4.8e-23 81.8 0.2 6.6e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS60117.1 - 5.2e-10 39.2 0.1 9.3e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS60117.1 - 3.2e-07 30.3 0.0 4.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS60117.1 - 0.0011 18.9 0.1 0.0081 16.1 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS60117.1 - 0.038 12.6 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNase_P_p30 PF01876.11 ETS60118.1 - 1.8e-48 163.5 0.0 3.2e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 Erf4 PF10256.4 ETS60119.1 - 9.5e-10 38.3 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.1 ETS60119.1 - 1.5e-05 25.0 0.0 5.6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Esterase_phd PF10503.4 ETS60120.1 - 9.7e-05 21.7 0.1 0.00017 20.8 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.6 ETS60120.1 - 0.0026 17.4 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 ETS60120.1 - 0.0077 16.1 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS60120.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS60120.1 - 0.036 13.2 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pyridox_oxidase PF01243.15 ETS60121.1 - 0.0086 16.0 0.0 0.023 14.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Zn_clus PF00172.13 ETS60122.1 - 0.00087 19.1 7.3 0.0026 17.6 5.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 ETS60123.1 - 8.4e-27 94.1 0.9 1.3e-26 93.5 0.6 1.2 1 0 0 1 1 1 1 RTA1 like protein FAD_binding_4 PF01565.18 ETS60124.1 - 4.4e-18 65.0 1.5 2.4e-15 56.2 1.0 2.5 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS60124.1 - 1.4e-07 31.2 0.0 4.8e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like BNR PF02012.15 ETS60124.1 - 5.8 7.1 6.1 1.2 9.2 0.1 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Aldo_ket_red PF00248.16 ETS60125.1 - 3.7e-60 203.1 0.0 4.6e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2780 PF11075.3 ETS60125.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) DUF1772 PF08592.6 ETS60126.1 - 1.7e-29 102.3 9.0 2.9e-29 101.5 5.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) UPF0104 PF03706.8 ETS60126.1 - 0.12 11.5 12.0 0.16 11.1 8.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Methyltransf_31 PF13847.1 ETS60127.1 - 8.4e-24 83.8 0.0 2e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60127.1 - 8.8e-24 83.8 0.0 2.2e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS60127.1 - 6.7e-16 58.5 0.0 1.5e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS60127.1 - 2.3e-15 57.1 0.1 1.6e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS60127.1 - 7.8e-15 54.9 0.0 1.4e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS60127.1 - 1.2e-14 54.4 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS60127.1 - 2.2e-13 49.8 0.0 5.4e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS60127.1 - 1.4e-08 34.7 0.1 3.7e-08 33.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS60127.1 - 4.2e-07 29.7 0.0 6.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 ETS60127.1 - 4.4e-07 29.4 0.0 7.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 ETS60127.1 - 3.3e-05 22.7 0.0 7e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 ETS60127.1 - 5.3e-05 22.6 0.0 0.0032 16.8 0.0 2.2 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.7 ETS60127.1 - 0.00046 19.1 0.0 0.0022 16.9 0.0 1.8 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.10 ETS60127.1 - 0.00058 19.5 0.0 0.0056 16.3 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 ETS60127.1 - 0.00076 18.5 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CheR PF01739.13 ETS60127.1 - 0.0018 17.6 0.0 0.86 8.8 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 ETS60127.1 - 0.0028 17.3 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 ETS60127.1 - 0.0052 15.6 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme RrnaAD PF00398.15 ETS60127.1 - 0.0068 15.4 0.0 0.021 13.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 ETS60127.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.8 ETS60127.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 ETS60127.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 ETS60127.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Lyase_1 PF00206.15 ETS60129.1 - 1.3e-95 320.2 0.0 1.7e-95 319.8 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 ETS60129.1 - 3.6e-28 97.4 0.0 7.4e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Glyco_transf_21 PF13506.1 ETS60130.1 - 1.5e-19 69.9 0.3 9.7e-08 31.4 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 ETS60130.1 - 5.4e-11 42.7 0.2 3.1e-10 40.2 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 KAR9 PF08580.5 ETS60131.1 - 4.4e-05 21.9 0.0 4.4e-05 21.9 0.0 4.6 4 1 1 5 5 5 1 Yeast cortical protein KAR9 GAS2 PF02187.12 ETS60131.1 - 0.0082 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.16 ETS60131.1 - 0.33 11.2 5.7 5.3 7.3 0.1 3.8 4 0 0 4 4 4 0 Spectrin repeat Ribosomal_L27 PF01016.14 ETS60132.1 - 8.1e-32 108.8 0.1 1.3e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Tim17 PF02466.14 ETS60133.1 - 3.5e-25 88.4 5.6 5.1e-25 87.9 3.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PTP_N PF12453.3 ETS60133.1 - 0.017 14.7 0.5 0.081 12.5 0.3 2.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Fungal_trans PF04082.13 ETS60134.1 - 6.6e-15 54.6 0.0 1.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS60134.1 - 0.00029 20.6 11.3 0.00054 19.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHF5 PF03660.9 ETS60135.1 - 7.3e-48 161.0 7.2 8.9e-48 160.8 5.0 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 ETS60135.1 - 0.19 11.5 9.8 0.66 9.8 4.6 2.4 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 ETS60135.1 - 0.37 10.5 11.1 2.5 7.9 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 ETS60135.1 - 1.4 8.6 8.2 2.9 7.6 4.9 2.3 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 ETS60135.1 - 1.5 8.5 12.2 2.8 7.6 0.3 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.4 ETS60135.1 - 1.9 8.5 8.9 0.97 9.4 1.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.7 ETS60135.1 - 3.1 7.6 9.1 49 3.8 5.1 2.3 1 1 1 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.7 ETS60135.1 - 4.1 6.8 12.4 2.3 7.5 1.1 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding ELMO_CED12 PF04727.8 ETS60136.1 - 2.7e-34 118.1 0.0 4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 ETS60136.1 - 4.1e-08 33.0 0.0 3.9e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Coq4 PF05019.8 ETS60137.1 - 2.8e-62 209.5 0.0 5.6e-50 169.3 0.0 2.1 1 1 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF3357 PF11837.3 ETS60139.1 - 0.25 11.1 3.3 2.4 8.0 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF3357) DUF4131 PF13567.1 ETS60139.1 - 2.2 7.6 11.0 29 4.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2615 PF11027.3 ETS60139.1 - 2.7 7.9 5.3 15 5.5 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2615) ABC2_membrane PF01061.19 ETS60139.1 - 8.8 5.4 12.8 3.4 6.7 4.9 2.7 3 0 0 3 3 3 0 ABC-2 type transporter Melibiase PF02065.13 ETS60140.1 - 3.2e-14 52.4 0.0 1.8e-09 36.7 0.0 2.6 2 1 0 2 2 2 2 Melibiase FMN_dh PF01070.13 ETS60141.1 - 7e-114 380.3 0.0 1.4e-113 379.4 0.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF4646 PF15496.1 ETS60141.1 - 5.9e-35 120.0 0.0 1.3e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) IMPDH PF00478.20 ETS60141.1 - 0.00079 18.4 0.2 0.0014 17.6 0.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETS60141.1 - 0.0017 17.5 1.3 0.0028 16.8 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 ETS60141.1 - 0.0025 16.8 0.1 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 ETS60141.1 - 0.0042 16.1 0.1 0.87 8.6 0.0 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 ETS60141.1 - 0.1 11.8 0.0 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein SR-25 PF10500.4 ETS60141.1 - 0.19 11.1 21.6 0.029 13.8 10.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 ETS60141.1 - 0.76 7.7 6.0 1.2 7.0 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Amidase PF01425.16 ETS60142.1 - 2.5e-104 349.5 4.0 1.4e-103 347.1 2.8 2.0 1 1 0 1 1 1 1 Amidase Response_reg PF00072.19 ETS60144.1 - 1.7e-15 56.9 0.0 2.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Tropomyosin_1 PF12718.2 ETS60145.1 - 2.5e-43 147.3 23.1 4.1e-43 146.6 16.0 1.3 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 ETS60145.1 - 2.5e-10 39.8 22.2 6.7e-07 28.6 7.1 2.3 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 ETS60145.1 - 0.00014 21.1 19.2 0.0002 20.5 13.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 ETS60145.1 - 0.0015 17.8 17.7 0.031 13.5 4.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) FlxA PF14282.1 ETS60145.1 - 0.0046 16.8 11.4 0.0078 16.1 0.6 2.9 1 1 2 3 3 3 1 FlxA-like protein CENP-F_leu_zip PF10473.4 ETS60145.1 - 0.012 15.5 22.7 0.16 11.8 1.2 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETS60145.1 - 0.027 14.0 20.8 0.047 13.2 14.4 1.4 1 0 0 1 1 1 0 IncA protein Trp_oprn_chp PF09534.5 ETS60145.1 - 0.039 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Myosin_tail_1 PF01576.14 ETS60145.1 - 0.047 11.4 22.9 0.063 10.9 15.8 1.1 1 0 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 ETS60145.1 - 0.066 12.3 5.8 0.17 11.0 0.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3287 PF11690.3 ETS60145.1 - 0.074 13.1 8.8 0.18 11.8 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) BLOC1_2 PF10046.4 ETS60145.1 - 0.16 12.1 13.3 0.75 9.9 2.3 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 ETS60145.1 - 0.19 10.1 12.3 0.24 9.7 8.5 1.1 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 ETS60145.1 - 0.21 11.4 25.1 0.32 10.8 1.7 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 ETS60145.1 - 0.21 11.4 16.7 0.3 10.9 9.9 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-Q PF13094.1 ETS60145.1 - 0.27 11.2 22.7 0.93 9.5 5.9 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 ETS60145.1 - 0.28 10.1 22.8 0.57 9.1 6.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 bZIP_1 PF00170.16 ETS60145.1 - 0.3 11.0 15.4 0.51 10.3 2.0 3.5 2 1 1 3 3 3 0 bZIP transcription factor ATG16 PF08614.6 ETS60145.1 - 0.36 10.6 23.7 1.4 8.7 6.2 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF812 PF05667.6 ETS60145.1 - 0.37 9.2 19.9 1.1 7.7 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) LMBR1 PF04791.11 ETS60145.1 - 0.39 9.2 7.7 0.037 12.6 1.7 1.7 1 1 1 2 2 2 0 LMBR1-like membrane protein KLRAQ PF10205.4 ETS60145.1 - 0.41 10.7 14.2 0.77 9.8 3.1 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4140 PF13600.1 ETS60145.1 - 0.43 11.0 16.3 0.99 9.8 3.3 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2968 PF11180.3 ETS60145.1 - 0.45 9.8 16.6 0.48 9.7 6.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3584 PF12128.3 ETS60145.1 - 0.5 7.6 19.9 0.25 8.6 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF641 PF04859.7 ETS60145.1 - 0.62 9.8 15.0 0.47 10.2 1.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.3 ETS60145.1 - 0.65 9.8 22.4 0.95 9.3 6.2 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 ETS60145.1 - 0.69 9.4 18.1 5 6.6 3.7 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 ETS60145.1 - 0.77 8.3 18.7 0.67 8.5 11.3 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.1 ETS60145.1 - 0.79 9.6 20.7 0.79 9.6 8.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.14 ETS60145.1 - 0.84 9.1 28.5 0.026 14.0 13.7 2.2 2 1 1 3 3 2 0 Ezrin/radixin/moesin family Borrelia_P83 PF05262.6 ETS60145.1 - 1.1 7.4 18.2 1.4 7.1 12.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.1 ETS60145.1 - 1.2 8.0 17.6 2.4 7.0 11.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_27 PF13514.1 ETS60145.1 - 1.2 6.7 21.2 0.32 8.6 11.2 1.7 1 1 1 2 2 2 0 AAA domain SlyX PF04102.7 ETS60145.1 - 1.3 9.4 12.0 4.4 7.7 1.2 3.1 2 2 1 3 3 2 0 SlyX Fib_alpha PF08702.5 ETS60145.1 - 1.5 8.9 9.4 3.8 7.6 6.0 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 ETS60145.1 - 1.9 8.0 17.0 4.8 6.7 11.0 2.1 1 1 0 1 1 1 0 Mnd1 family DUF4559 PF15112.1 ETS60145.1 - 2.2 7.3 12.5 3.8 6.5 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CENP-K PF11802.3 ETS60145.1 - 2.9 7.0 10.9 0.14 11.4 2.2 2.1 1 1 1 2 2 2 0 Centromere-associated protein K PspA_IM30 PF04012.7 ETS60145.1 - 3.2 7.0 23.2 0.76 9.0 3.0 2.8 1 1 2 3 3 3 0 PspA/IM30 family CCDC155 PF14662.1 ETS60145.1 - 3.2 7.2 23.4 7.7 6.0 16.2 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 WXG100 PF06013.7 ETS60145.1 - 3.4 7.7 7.5 15 5.6 0.9 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF919 PF06034.6 ETS60145.1 - 3.4 7.3 7.1 2.3 7.8 0.4 2.7 3 0 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Cluap1 PF10234.4 ETS60145.1 - 3.5 6.7 16.8 26 3.8 10.9 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 NPV_P10 PF05531.7 ETS60145.1 - 3.6 7.9 8.1 3.3 8.0 1.1 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 ETS60145.1 - 3.7 7.4 5.8 7.4 6.5 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HAP1_N PF04849.8 ETS60145.1 - 3.9 6.3 19.4 6.1 5.7 13.4 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Nup54 PF13874.1 ETS60145.1 - 4.4 6.9 13.9 12 5.5 3.8 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 YlqD PF11068.3 ETS60145.1 - 4.4 7.3 12.6 2.6 8.0 6.2 2.3 1 1 2 3 3 3 0 YlqD protein Phage_GP20 PF06810.6 ETS60145.1 - 4.5 6.6 17.8 5.3 6.4 9.1 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF1664 PF07889.7 ETS60145.1 - 4.7 7.0 10.6 1.8 8.3 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 ETS60145.1 - 4.7 6.9 18.4 6.7 6.4 10.4 2.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.6 ETS60145.1 - 5.2 6.9 9.8 6.7 6.5 0.9 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Uds1 PF15456.1 ETS60145.1 - 5.3 7.0 20.2 11 5.9 10.5 2.9 1 1 2 3 3 3 0 Up-regulated During Septation Laminin_II PF06009.7 ETS60145.1 - 5.7 6.6 12.2 1.7 8.3 2.3 2.3 1 1 1 2 2 2 0 Laminin Domain II Spectrin PF00435.16 ETS60145.1 - 7.2 6.9 17.7 0.92 9.8 4.8 3.1 1 1 1 2 2 2 0 Spectrin repeat GBP_C PF02841.9 ETS60145.1 - 7.6 5.6 16.6 17 4.4 11.2 1.5 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.14 ETS60145.1 - 8.3 4.1 13.6 13 3.4 9.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3552 PF12072.3 ETS60145.1 - 8.4 5.5 22.6 4.2 6.5 8.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Kinesin PF00225.18 ETS60146.1 - 8.4e-97 323.8 0.0 8.4e-97 323.8 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain DUF812 PF05667.6 ETS60146.1 - 0.0048 15.4 18.0 0.008 14.7 12.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.1 ETS60146.1 - 0.0056 15.8 1.9 0.0056 15.8 1.3 3.0 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding UpxZ PF06603.6 ETS60146.1 - 0.018 15.0 0.0 0.26 11.3 0.0 2.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DMPK_coil PF08826.5 ETS60146.1 - 0.032 14.1 0.3 0.032 14.1 0.2 3.9 3 1 1 4 4 4 0 DMPK coiled coil domain like AAA_24 PF13479.1 ETS60146.1 - 0.057 12.9 0.1 11 5.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 ETS60146.1 - 0.15 11.2 12.2 0.02 14.1 1.6 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 ETS60146.1 - 1.2 8.9 2.9 16 5.3 0.0 3.8 5 0 0 5 5 5 0 DASH complex subunit Dam1 Atg14 PF10186.4 ETS60146.1 - 3.9 6.3 27.9 0.25 10.2 4.9 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GP41 PF00517.12 ETS60146.1 - 4 6.9 8.6 3.3 7.1 0.8 2.6 2 1 0 2 2 2 0 Retroviral envelope protein TRAUB PF08164.7 ETS60147.1 - 9.6e-27 92.9 0.5 1.3e-25 89.2 0.0 2.7 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 ETS60147.1 - 2e-21 76.5 0.8 2e-21 76.5 0.6 2.9 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor Nsp1_C PF05064.8 ETS60148.1 - 2.6e-30 104.4 0.0 5.7e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 ETS60148.1 - 0.001 19.2 190.1 0.41 10.9 42.4 5.7 1 1 2 3 3 3 1 Nucleoporin FG repeat region Baculo_PEP_C PF04513.7 ETS60148.1 - 0.13 12.1 3.1 0.33 10.7 0.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L2_C PF03947.13 ETS60150.1 - 1.1e-45 154.5 1.6 3e-45 153.2 1.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 ETS60150.1 - 7.7e-26 89.8 0.4 1.5e-25 88.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DnaJ PF00226.26 ETS60150.1 - 7.1e-20 70.5 0.2 1.6e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3166 PF11365.3 ETS60150.1 - 2.5 8.6 9.4 0.35 11.3 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) Glyco_transf_22 PF03901.12 ETS60151.1 - 2.3e-46 158.6 11.5 2.9e-46 158.3 8.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TPR_11 PF13414.1 ETS60153.1 - 1.8e-15 56.3 1.1 2.6e-08 33.3 0.1 5.5 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 ETS60153.1 - 1.1e-08 34.3 2.1 0.0099 15.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS60153.1 - 1.6e-07 30.6 13.1 0.00074 19.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS60153.1 - 2.8e-06 27.0 3.6 0.0013 18.5 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS60153.1 - 2.1e-05 24.3 0.4 0.00032 20.5 0.1 5.5 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS60153.1 - 2.7e-05 23.9 0.5 1.3 9.4 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS60153.1 - 3.7e-05 23.7 1.0 0.00027 21.0 0.2 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETS60153.1 - 0.00013 22.5 2.0 0.0014 19.2 1.6 7.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS60153.1 - 0.00052 19.6 1.9 0.21 11.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS60153.1 - 0.0021 17.7 2.5 6.2 6.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS60153.1 - 0.04 14.5 0.2 0.04 14.5 0.1 8.9 9 1 1 10 10 8 0 Tetratricopeptide repeat DUF3835 PF12927.2 ETS60154.1 - 0.0079 17.1 3.1 0.0079 17.1 2.2 5.1 6 1 0 6 6 6 2 Domain of unknown function (DUF3835) Cupin_8 PF13621.1 ETS60156.1 - 4.9e-07 29.5 0.0 1.8e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETS60156.1 - 1.7e-05 24.9 0.2 0.001 19.2 0.2 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 ETS60156.1 - 2.6e-05 23.7 14.2 6.5e-05 22.5 9.9 1.7 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS60156.1 - 0.1 11.9 15.0 0.019 14.2 7.6 1.9 2 0 0 2 2 2 0 PHD-finger Ammonium_transp PF00909.16 ETS60157.1 - 1.2e-104 349.9 27.0 1.4e-104 349.7 18.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2015 PF09435.5 ETS60158.1 - 1.1e-26 93.0 0.3 5.9e-26 90.7 0.0 1.8 1 1 0 2 2 2 1 Fungal protein of unknown function (DUF2015) DNA_pol_B PF00136.16 ETS60159.1 - 4.2e-112 375.2 0.0 5.8e-112 374.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 ETS60159.1 - 1.8e-60 203.5 0.6 3.2e-60 202.7 0.4 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 ETS60159.1 - 1.2e-27 96.6 0.0 1.9e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 ETS60159.1 - 4.6e-20 71.2 6.2 4.6e-20 71.2 4.3 3.2 4 0 0 4 4 4 1 DNA polymerase alpha subunit p180 N terminal Nop14 PF04147.7 ETS60159.1 - 3.8 5.3 13.7 5.7 4.7 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family Mito_carr PF00153.22 ETS60160.1 - 1e-27 95.6 3.8 1.8e-15 56.4 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein PRKCSH PF07915.8 ETS60161.1 - 1.5e-11 44.9 2.2 5.1e-10 40.0 0.4 3.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 ETS60161.1 - 0.034 13.6 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein PX PF00787.19 ETS60162.1 - 2.1e-20 72.6 0.0 5.2e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 ETS60162.1 - 6.6e-05 22.2 9.3 0.0011 18.2 0.5 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 ETS60162.1 - 0.078 12.4 7.6 0.042 13.3 0.4 2.2 2 0 0 2 2 2 0 BAR domain FAD_binding_4 PF01565.18 ETS60163.1 - 9.6e-22 76.9 0.6 1.6e-21 76.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3515 PF12028.3 ETS60163.1 - 0.1 11.7 1.7 0.21 10.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) Exo5 PF09810.4 ETS60165.1 - 1.2e-38 133.1 0.0 7.7e-36 123.9 0.0 2.0 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease GPI2 PF06432.6 ETS60166.1 - 2.8e-49 167.9 4.3 3.7e-49 167.5 3.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase FA_desaturase PF00487.19 ETS60166.1 - 6.6 6.0 9.3 0.93 8.8 2.8 2.0 1 1 0 2 2 2 0 Fatty acid desaturase MFS_1 PF07690.11 ETS60168.1 - 9.7e-29 100.1 25.0 3.3e-28 98.4 17.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_kinase PF01513.16 ETS60169.1 - 8.3e-54 182.2 0.0 1e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF1014 PF06244.7 ETS60170.1 - 1.8e-27 95.9 6.8 9.1e-27 93.6 4.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF2852 PF11014.3 ETS60170.1 - 8.3 6.4 8.8 1.4 8.8 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) Rhodanese PF00581.15 ETS60171.1 - 8.4e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain UQ_con PF00179.21 ETS60172.1 - 2.9e-46 156.3 0.0 3.7e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS60172.1 - 0.0027 17.4 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS60172.1 - 0.17 11.7 0.2 0.18 11.7 0.2 1.4 1 1 0 1 1 1 0 RWD domain Pkinase PF00069.20 ETS60173.1 - 5.8e-58 196.0 0.4 1e-57 195.2 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60173.1 - 7.3e-22 77.6 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS60173.1 - 0.0083 14.9 0.2 0.013 14.2 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 ETS60173.1 - 0.035 13.4 0.2 0.12 11.7 0.2 1.8 1 1 0 1 1 1 0 RIO1 family CLASP_N PF12348.3 ETS60175.1 - 1.2e-81 273.4 2.2 4.5e-69 232.2 0.0 3.4 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 ETS60175.1 - 5.9e-08 32.1 1.3 0.82 9.9 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat Dopey_N PF04118.9 ETS60175.1 - 0.016 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 Dopey, N-terminal UPF0029 PF01205.14 ETS60176.1 - 2e-16 59.6 0.2 1.4e-15 56.9 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 Telomere_Sde2_2 PF13297.1 ETS60176.1 - 0.06 12.6 0.4 0.13 11.5 0.3 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal RPN7 PF10602.4 ETS60177.1 - 3.9e-51 172.9 0.0 6.6e-51 172.1 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 ETS60177.1 - 5.4e-11 42.7 0.0 2.6e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 ETS60177.1 - 0.0017 18.1 0.8 0.27 11.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS60177.1 - 0.0072 15.9 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 ETS60177.1 - 0.012 15.3 0.1 1.6 8.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ATHILA PF03078.10 ETS60177.1 - 0.11 11.1 0.3 0.14 10.7 0.2 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family RNase_PH PF01138.16 ETS60178.1 - 2.5e-32 111.9 0.9 4.1e-32 111.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 MS_channel PF00924.13 ETS60179.1 - 1.4e-19 70.2 0.4 2.1e-19 69.6 0.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 ETS60179.1 - 0.00032 19.8 0.1 0.00065 18.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETS60179.1 - 0.0018 17.9 0.1 0.0049 16.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETS60179.1 - 0.0035 16.6 0.2 0.0079 15.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETS60179.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 ETS60179.1 - 0.027 14.6 0.1 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Cyclin_N PF00134.18 ETS60180.1 - 2.5e-10 39.9 0.4 5.8e-08 32.3 0.0 2.9 3 0 0 3 3 3 2 Cyclin, N-terminal domain TFIIB PF00382.14 ETS60180.1 - 0.00032 20.4 0.0 2.5 7.9 0.0 3.4 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.14 ETS60180.1 - 0.083 12.8 0.2 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Cyclin, C-terminal domain Bax1-I PF01027.15 ETS60181.1 - 1.5e-32 112.9 9.6 2.2e-32 112.3 6.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 HEAT_EZ PF13513.1 ETS60182.1 - 1.2e-31 108.3 10.5 6.7e-06 26.4 0.0 11.7 10 2 1 11 11 11 6 HEAT-like repeat HEAT_2 PF13646.1 ETS60182.1 - 2.4e-25 88.6 13.7 3.6e-06 27.1 0.0 8.7 5 4 5 10 10 10 7 HEAT repeats HEAT PF02985.17 ETS60182.1 - 3.1e-20 70.3 14.7 0.0043 17.0 0.1 11.3 13 0 0 13 13 13 4 HEAT repeat UME PF08064.8 ETS60182.1 - 1.1e-10 41.3 0.1 0.00067 19.5 0.0 5.5 4 2 0 4 4 4 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 ETS60182.1 - 2.1e-09 37.6 0.0 0.031 14.6 0.0 5.5 6 0 0 6 6 5 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 ETS60182.1 - 2.3e-09 37.0 0.4 1.2e-08 34.7 0.0 2.6 3 0 0 3 3 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 ETS60182.1 - 7.1e-09 34.5 1.5 0.14 10.4 0.1 4.7 5 0 0 5 5 5 3 Adaptin N terminal region Ipi1_N PF12333.3 ETS60182.1 - 1.2e-08 34.8 0.0 0.11 12.4 0.0 6.4 6 1 1 7 7 7 2 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.3 ETS60182.1 - 4.1e-07 29.5 0.0 0.11 11.8 0.0 4.9 4 1 0 4 4 4 2 CLASP N terminal Xpo1 PF08389.7 ETS60182.1 - 1.7e-06 27.9 8.0 0.0049 16.7 0.3 6.3 6 1 0 6 6 6 1 Exportin 1-like protein Cohesin_HEAT PF12765.2 ETS60182.1 - 2.6e-05 24.0 1.7 0.0082 16.0 0.1 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.3 ETS60182.1 - 8.1e-05 22.2 0.0 0.032 13.9 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Cnd1 PF12717.2 ETS60182.1 - 0.00041 20.2 0.0 0.79 9.5 0.0 4.3 3 3 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 ETS60182.1 - 0.00094 18.0 2.0 5.2 5.6 0.0 5.4 6 2 1 8 8 8 1 RNAPII transcription regulator C-terminal Ric8 PF10165.4 ETS60182.1 - 0.0053 15.6 0.6 0.25 10.1 0.0 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor synembryn Arm PF00514.18 ETS60182.1 - 0.011 15.5 13.1 16 5.4 0.0 7.8 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 ETS60182.1 - 0.029 14.2 0.2 20 5.1 0.0 4.2 4 0 0 4 4 3 0 Protein of unknown function (DUF2435) Myosin_head PF00063.16 ETS60183.1 - 1.7e-244 813.0 0.5 3.1e-244 812.1 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 ETS60183.1 - 3.9e-35 119.8 1.6 1.2e-34 118.2 1.1 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 ETS60183.1 - 2.1e-19 67.2 29.1 4.5e-05 22.7 0.1 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 ETS60183.1 - 0.0026 17.8 0.0 0.013 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain PIN PF01850.16 ETS60183.1 - 0.027 14.7 2.5 0.075 13.3 1.5 2.0 1 1 0 1 1 1 0 PIN domain TPR_MLP1_2 PF07926.7 ETS60183.1 - 0.048 13.3 17.9 0.078 12.7 3.0 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 ETS60183.1 - 0.24 11.2 16.1 0.078 12.8 3.6 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1192 PF06698.6 ETS60183.1 - 0.88 9.4 12.4 0.8 9.5 4.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 ETS60183.1 - 1.7 9.0 8.5 9.2 6.6 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ubiquitin PF00240.18 ETS60184.1 - 1.8e-18 65.6 2.5 2.3e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETS60184.1 - 1.9e-10 40.2 0.4 2.9e-06 26.8 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 ETS60184.1 - 1.2e-09 37.8 8.9 3e-09 36.5 6.2 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD_2 PF13881.1 ETS60184.1 - 0.017 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 ETS60184.1 - 0.026 14.3 3.3 0.039 13.8 2.3 1.3 1 0 0 1 1 1 0 IBR domain zf-CSL PF05207.8 ETS60184.1 - 0.07 12.6 0.4 0.12 11.8 0.3 1.5 1 0 0 1 1 1 0 CSL zinc finger SMC_Nse1 PF07574.8 ETS60185.1 - 3.8e-19 69.0 3.5 1.1e-16 61.0 2.4 2.2 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 ETS60185.1 - 5.8e-05 23.0 4.5 5.8e-05 23.0 3.1 1.8 2 0 0 2 2 2 1 RING-like domain zf-HC5HC2H PF13771.1 ETS60185.1 - 0.00053 20.0 1.7 0.0012 18.9 1.2 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 ETS60185.1 - 0.0008 19.3 0.3 0.0021 18.0 0.2 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain C1_1 PF00130.17 ETS60185.1 - 0.8 9.4 8.3 0.3 10.8 3.5 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Apc11 PF12861.2 ETS60185.1 - 1.1 9.1 4.4 3.1 7.7 3.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 ETS60185.1 - 4.6 7.1 12.7 1.9 8.3 5.3 2.5 2 0 0 2 2 2 0 Ring finger domain Sugar_tr PF00083.19 ETS60186.1 - 1.3e-85 287.6 20.6 1.6e-85 287.4 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS60186.1 - 1.6e-17 63.3 46.4 6.8e-17 61.2 12.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 ETS60188.1 - 1.1e-86 291.0 0.0 1.3e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PfkB PF00294.19 ETS60189.1 - 6.4e-36 124.0 0.2 7.8e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase efThoc1 PF11957.3 ETS60192.1 - 9.3e-96 321.2 0.8 8.2e-45 153.2 0.0 3.6 2 1 1 3 3 3 3 THO complex subunit 1 transcription elongation factor RPN7 PF10602.4 ETS60193.1 - 1.4e-54 184.1 1.5 2.4e-54 183.4 1.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 ETS60193.1 - 1.3e-15 57.5 0.1 4.8e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain RRM_1 PF00076.17 ETS60193.1 - 1e-13 50.6 0.0 2.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60193.1 - 5e-12 45.6 0.1 2.6e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60193.1 - 0.00015 21.5 0.0 0.00037 20.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP PF03399.11 ETS60193.1 - 0.027 14.0 0.4 0.043 13.3 0.3 1.3 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Pribosyltran PF00156.22 ETS60194.1 - 4.3e-16 58.7 0.1 6.3e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETS60194.1 - 0.00084 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SHR3_chaperone PF08229.6 ETS60197.1 - 1.2e-27 96.1 0.0 1.9e-27 95.4 0.0 1.2 1 1 0 1 1 1 1 ER membrane protein SH3 SecG PF03840.9 ETS60197.1 - 0.027 14.1 0.3 0.027 14.1 0.2 1.7 2 0 0 2 2 2 0 Preprotein translocase SecG subunit UQ_con PF00179.21 ETS60198.1 - 5e-20 71.3 0.0 8.3e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETS60198.1 - 0.032 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain DnaJ PF00226.26 ETS60199.1 - 1.9e-23 81.9 0.3 2.9e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain TP2 PF01254.13 ETS60200.1 - 0.45 10.8 4.3 0.39 11.0 2.0 1.6 1 1 1 2 2 2 0 Nuclear transition protein 2 SET PF00856.23 ETS60200.1 - 0.58 10.4 3.5 0.65 10.2 2.4 1.1 1 0 0 1 1 1 0 SET domain DHHW PF14286.1 ETS60200.1 - 3 7.0 7.9 3.7 6.7 5.5 1.1 1 0 0 1 1 1 0 DHHW protein RR_TM4-6 PF06459.7 ETS60200.1 - 3 7.6 13.5 3.3 7.5 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.6 ETS60200.1 - 6.1 4.9 16.8 7.1 4.7 11.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein OPT PF03169.10 ETS60201.1 - 1e-161 539.5 35.4 1.2e-161 539.3 24.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein VIT1 PF01988.14 ETS60201.1 - 0.16 11.4 8.2 0.93 8.9 0.2 3.5 4 0 0 4 4 4 0 VIT family Gar1 PF04410.9 ETS60202.1 - 8.6e-40 135.7 0.1 8.6e-40 135.7 0.1 2.3 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region zf-HIT PF04438.11 ETS60203.1 - 7.6e-10 38.2 11.8 1.2e-09 37.5 8.2 1.4 1 0 0 1 1 1 1 HIT zinc finger EPL1 PF10513.4 ETS60203.1 - 0.0039 17.4 2.3 0.0088 16.2 1.6 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like TP6A_N PF04406.9 ETS60203.1 - 0.069 12.8 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Type IIB DNA topoisomerase EF-1_beta_acid PF10587.4 ETS60203.1 - 0.2 11.8 3.9 0.44 10.7 2.7 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region zf-Mss51 PF13824.1 ETS60203.1 - 0.68 9.8 5.6 1.5 8.6 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 An_peroxidase PF03098.10 ETS60204.1 - 1.4e-82 277.7 0.0 9.2e-81 271.8 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 ETS60204.1 - 0.019 13.4 0.0 0.034 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome P450 SSF PF00474.12 ETS60205.1 - 8.7e-22 77.3 32.4 1.3e-21 76.7 22.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Peptidase_C97 PF05903.9 ETS60206.1 - 1.2e-35 122.4 0.0 2.1e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 ETS60206.1 - 2.3e-21 75.7 0.2 3.9e-21 75.0 0.2 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 ETS60206.1 - 9.3e-09 34.9 0.0 2.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS60206.1 - 0.00041 20.5 0.1 0.0016 18.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain PITH PF06201.8 ETS60207.1 - 2.7e-35 121.3 0.0 4.6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 ETS60207.1 - 4e-21 74.6 0.1 1.3e-20 73.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS60207.1 - 0.0011 19.1 0.1 0.19 11.9 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS60207.1 - 0.0015 18.5 0.1 0.29 11.2 0.1 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 ETS60207.1 - 0.037 14.0 0.6 0.19 11.8 0.4 2.1 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 ETS60207.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF202 PF02656.10 ETS60208.1 - 4e-11 42.9 0.6 4e-11 42.9 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) P19Arf_N PF07392.7 ETS60208.1 - 1.4 9.0 8.5 0.39 10.9 2.6 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus HLH PF00010.21 ETS60210.1 - 1.7e-08 33.9 0.6 3.6e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain NBP1 PF08537.5 ETS60210.1 - 0.001 18.3 1.5 0.0015 17.8 1.0 1.2 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF3135 PF11333.3 ETS60210.1 - 0.068 13.3 0.6 0.17 12.0 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) RhoGAP PF00620.22 ETS60211.1 - 4.1e-46 156.3 0.0 7.3e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 ETS60211.1 - 1.8e-14 53.6 0.2 1.2e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Pkinase PF00069.20 ETS60212.1 - 3.9e-72 242.5 0.0 5.1e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60212.1 - 5.6e-47 159.9 0.0 7.8e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 ETS60212.1 - 8.5e-22 77.3 0.0 2.3e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 ETS60212.1 - 9.5e-06 24.7 0.0 2.7e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETS60212.1 - 0.0058 16.3 0.3 0.19 11.4 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family DSHCT PF08148.7 ETS60212.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 ETS60212.1 - 0.14 11.1 0.3 0.79 8.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 ETS60212.1 - 0.16 11.1 0.1 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Rad9 PF04139.8 ETS60213.1 - 6e-52 176.2 0.0 7.1e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Rad9 RINGv PF12906.2 ETS60214.1 - 8.7e-15 54.4 10.7 1.5e-14 53.7 7.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 ETS60214.1 - 0.4 10.5 11.4 0.74 9.6 7.9 1.5 1 0 0 1 1 1 0 Ring finger domain DEAD PF00270.24 ETS60215.1 - 7.4e-43 145.9 0.0 1.1e-41 142.1 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS60215.1 - 7e-23 80.2 0.0 2.9e-22 78.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.18 ETS60215.1 - 0.0023 17.7 0.5 0.0039 17.0 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL32 PF06070.6 ETS60215.1 - 0.013 14.0 3.4 0.018 13.5 2.3 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 zf-CCHC_4 PF14392.1 ETS60215.1 - 0.085 12.5 0.5 0.18 11.4 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Phage_endo_I PF05367.6 ETS60215.1 - 0.092 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Phage endonuclease I zf-CCHC_2 PF13696.1 ETS60215.1 - 0.15 11.6 0.3 0.38 10.2 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Med4 PF10018.4 ETS60216.1 - 5.4e-22 78.1 6.0 7.9e-22 77.5 4.2 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CDP-OH_P_transf PF01066.16 ETS60218.1 - 5.9e-12 45.7 2.7 5.9e-12 45.7 1.9 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UCH_1 PF13423.1 ETS60219.1 - 1.3e-46 159.4 0.0 1.8e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 ETS60219.1 - 3.1e-25 89.3 0.0 9.5e-23 81.2 0.0 2.4 2 0 0 2 2 2 2 Exonuclease UCH PF00443.24 ETS60219.1 - 0.00071 18.7 0.0 0.046 12.8 0.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 ETS60219.1 - 0.0095 15.7 0.2 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4647 PF15504.1 ETS60219.1 - 0.49 9.2 8.7 0.75 8.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) BTV_NS2 PF04514.7 ETS60219.1 - 3.5 6.4 9.1 8 5.2 6.3 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Zn_clus PF00172.13 ETS60221.1 - 2e-06 27.5 8.7 4.1e-06 26.5 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CK2S PF15011.1 ETS60221.1 - 0.012 15.3 0.3 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF2419 PF10343.4 ETS60222.1 - 0.00034 19.9 0.0 0.0052 16.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) DUF3446 PF11928.3 ETS60223.1 - 0.13 12.4 12.8 0.35 11.0 8.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Tim44 PF04280.10 ETS60224.1 - 1.9e-29 102.5 0.7 3.7e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain SAC3_GANP PF03399.11 ETS60225.1 - 3.6e-72 242.1 1.1 5.6e-72 241.5 0.7 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family BAG PF02179.11 ETS60225.1 - 5.5e-14 52.0 1.0 2.1e-13 50.1 0.7 2.1 1 0 0 1 1 1 1 BAG domain PCI_Csn8 PF10075.4 ETS60225.1 - 0.00019 21.2 0.9 0.0027 17.4 0.1 2.5 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 ubiquitin PF00240.18 ETS60225.1 - 0.00051 19.3 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family GHMP_kinases_N PF00288.21 ETS60226.1 - 2.7e-13 49.7 0.1 6.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS60226.1 - 0.00058 20.0 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal PRP38 PF03371.10 ETS60227.1 - 6.6e-57 191.8 0.0 8.1e-57 191.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF566 PF04484.7 ETS60227.1 - 7.2 6.0 11.3 11 5.4 7.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ctr PF04145.10 ETS60228.1 - 1.1e-07 32.0 13.5 0.00087 19.3 5.0 2.2 1 1 1 2 2 2 2 Ctr copper transporter family DUF2985 PF11204.3 ETS60228.1 - 0.15 11.8 4.5 0.35 10.6 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) DUF4231 PF14015.1 ETS60228.1 - 0.68 9.9 4.2 7.1 6.6 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) PrgI PF12666.2 ETS60228.1 - 2.3 8.4 5.8 6.5 6.9 4.0 1.7 1 1 0 1 1 1 0 PrgI family protein PAXIP1_C PF15364.1 ETS60229.1 - 1.4 8.8 7.4 0.82 9.5 2.2 2.3 1 1 1 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein AA_permease PF00324.16 ETS60230.1 - 9.9e-65 218.7 31.2 1.2e-64 218.4 21.6 1.1 1 0 0 1 1 1 1 Amino acid permease Actin PF00022.14 ETS60231.1 - 1.9e-21 75.9 0.0 1.3e-11 43.5 0.0 3.2 3 0 0 3 3 3 3 Actin TPR_19 PF14559.1 ETS60231.1 - 0.0033 17.7 9.2 0.19 12.0 1.7 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat NARP1 PF12569.3 ETS60231.1 - 0.017 13.9 0.0 0.036 12.8 0.0 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Clat_adaptor_s PF01217.15 ETS60232.1 - 7.4e-56 187.8 2.6 8.2e-56 187.6 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPR_11 PF13414.1 ETS60233.1 - 3.2e-13 49.1 5.3 1.8e-08 33.8 0.9 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETS60233.1 - 6.5e-07 28.7 3.6 0.0041 16.9 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS60233.1 - 1e-05 24.9 2.6 0.017 14.7 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS60233.1 - 0.00062 20.3 3.9 0.14 12.8 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS60233.1 - 0.0011 19.3 1.8 0.1 13.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS60233.1 - 0.0022 17.8 1.5 0.079 12.8 0.0 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS60233.1 - 0.022 14.5 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS60233.1 - 0.15 12.6 0.3 6.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS60233.1 - 0.26 11.6 2.4 0.22 11.8 0.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat NADH-u_ox-rdase PF10785.4 ETS60234.1 - 9.7e-35 118.6 0.2 1.6e-34 118.0 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 ETS60234.1 - 1.8e-13 49.9 0.0 3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit PseudoU_synth_1 PF01416.15 ETS60235.1 - 6.2e-22 78.0 0.0 4.6e-13 49.4 0.0 3.3 2 2 0 2 2 2 2 tRNA pseudouridine synthase DUF1771 PF08590.5 ETS60236.1 - 7.1e-15 54.7 5.6 7.1e-15 54.7 3.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 ETS60236.1 - 2.4e-07 30.8 0.1 7.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 ETS60236.1 - 2.6e-05 23.7 11.4 0.0026 17.4 1.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 ETS60236.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus Paf1 PF03985.8 ETS60237.1 - 1.5e-38 132.6 8.6 8.1e-36 123.6 0.0 4.6 2 2 2 4 4 4 2 Paf1 Zn_clus PF00172.13 ETS60238.1 - 9.5e-07 28.6 10.3 1.8e-06 27.7 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Skp1 PF01466.14 ETS60239.1 - 4.9e-37 125.8 0.3 8.9e-37 124.9 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 ETS60239.1 - 5.8e-25 87.1 0.2 1.6e-24 85.7 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 ETS60239.1 - 0.018 15.0 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain MTHFR PF02219.12 ETS60240.1 - 1.5e-111 372.0 0.0 2.5e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3479 PF11965.3 ETS60240.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) DUF2183 PF09949.4 ETS60241.1 - 8.7e-25 86.5 0.0 3.1e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 ETS60241.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) VHS PF00790.14 ETS60242.1 - 2.8e-29 101.5 0.5 6.5e-29 100.3 0.3 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 ETS60242.1 - 1.6e-16 59.5 0.1 3.4e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS60242.1 - 2.9e-16 58.5 0.0 6e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS60242.1 - 1.1e-12 47.1 0.1 2.1e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 ETS60242.1 - 0.0003 20.7 2.0 0.00049 20.0 0.1 2.3 2 0 0 2 2 2 1 GAT domain UIM PF02809.15 ETS60242.1 - 0.0063 15.9 2.8 0.0063 15.9 1.9 2.4 2 0 0 2 2 2 1 Ubiquitin interaction motif Hrs_helical PF12210.3 ETS60242.1 - 0.0073 16.5 2.4 0.012 15.8 0.2 2.3 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate TFIIA PF03153.8 ETS60242.1 - 3.7 7.3 28.1 0.11 12.3 3.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cyt-b5 PF00173.23 ETS60243.1 - 1.7e-18 66.1 0.0 2.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Hamartin PF04388.7 ETS60243.1 - 1.9 7.0 6.5 2.4 6.7 4.5 1.1 1 0 0 1 1 1 0 Hamartin protein DASH_Spc34 PF08657.5 ETS60244.1 - 1.5e-08 34.6 5.2 7.6e-08 32.3 0.1 2.9 2 2 0 2 2 2 1 DASH complex subunit Spc34 A_deaminase PF00962.17 ETS60245.1 - 3e-110 368.2 0.1 3.8e-110 367.9 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Rep_fac_C PF08542.6 ETS60246.1 - 4.2e-19 68.3 0.0 8.6e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 ETS60246.1 - 6.3e-17 62.0 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 ETS60246.1 - 1.5e-16 60.5 0.0 2e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 ETS60246.1 - 1.1e-11 44.1 0.0 9.1e-09 34.5 0.0 2.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 ETS60246.1 - 4e-06 26.9 0.1 0.028 14.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 ETS60246.1 - 2.5e-05 23.3 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 ETS60246.1 - 2.5e-05 23.4 0.0 6.2e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 ETS60246.1 - 2.6e-05 24.1 0.0 8e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS60246.1 - 4.2e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 ETS60246.1 - 5.9e-05 22.7 0.1 0.00021 20.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS60246.1 - 8.1e-05 22.6 0.0 0.0027 17.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 ETS60246.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS60246.1 - 0.00014 21.6 0.0 0.0014 18.3 0.0 2.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 ETS60246.1 - 0.0017 17.9 0.1 0.0066 16.0 0.1 1.9 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 ETS60246.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 ETS60246.1 - 0.0041 16.5 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ETS60246.1 - 0.0044 16.5 0.3 2.9 7.2 0.0 2.9 2 1 1 3 3 3 1 AAA-like domain DEAD PF00270.24 ETS60246.1 - 0.0081 15.6 0.1 0.13 11.7 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_3 PF07726.6 ETS60246.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 ETS60246.1 - 0.017 14.0 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 ETS60246.1 - 0.022 14.6 0.0 0.073 12.9 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 ETS60246.1 - 0.043 13.2 0.0 0.089 12.2 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 ETS60246.1 - 0.049 13.1 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 ETS60246.1 - 0.05 12.7 0.0 0.41 9.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 ETS60246.1 - 0.052 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS60246.1 - 0.083 13.0 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 1 0 RNA helicase WGG PF10273.4 ETS60246.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 1 0 Pre-rRNA-processing protein TSR2 AAA_17 PF13207.1 ETS60246.1 - 0.14 12.9 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nucleopor_Nup85 PF07575.8 ETS60247.1 - 1.8e-85 287.2 0.0 1.7e-51 175.1 0.4 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin zf-C2H2_jaz PF12171.3 ETS60248.1 - 2.1e-08 34.0 0.4 3.5e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 ETS60248.1 - 0.0053 16.8 0.0 0.0053 16.8 0.0 1.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 ETS60248.1 - 0.0075 16.4 0.2 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 ETS60248.1 - 0.051 13.9 0.4 0.051 13.9 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L35Ae PF01247.13 ETS60249.1 - 5.6e-41 138.2 3.1 7.7e-41 137.7 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 ETS60249.1 - 0.04 13.8 0.1 8.1 6.4 0.0 2.5 2 1 0 2 2 2 0 RimM N-terminal domain Scm3 PF10384.4 ETS60250.1 - 2.6e-19 68.4 0.2 2.6e-19 68.4 0.2 2.3 3 0 0 3 3 3 1 Centromere protein Scm3 dsrm PF00035.20 ETS60251.1 - 0.033 14.7 0.1 0.059 13.9 0.1 1.5 1 1 0 1 1 1 0 Double-stranded RNA binding motif ACC_central PF08326.7 ETS60252.1 - 3.6e-209 696.4 0.0 4.7e-209 696.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 ETS60252.1 - 7.3e-170 565.5 0.0 9.7e-170 565.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 ETS60252.1 - 2.2e-53 180.6 0.0 4.6e-53 179.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ETS60252.1 - 2.6e-24 85.4 0.1 6.7e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS60252.1 - 2.7e-21 75.5 0.0 8.4e-20 70.7 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 ETS60252.1 - 4.8e-14 51.7 0.2 1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 ETS60252.1 - 8.4e-14 51.7 0.0 2.5e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 ETS60252.1 - 3.7e-06 26.5 0.0 1.5e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 ETS60252.1 - 0.00026 20.4 0.0 0.00066 19.1 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 ETS60252.1 - 0.0007 18.9 0.1 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ETS60252.1 - 0.0021 17.9 0.2 0.0088 15.9 0.0 2.2 3 0 0 3 3 2 1 ATP-grasp domain RnfC_N PF13375.1 ETS60252.1 - 0.0086 15.7 0.5 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain RimK PF08443.6 ETS60252.1 - 0.016 14.6 0.0 0.15 11.5 0.0 2.3 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 ETS60252.1 - 0.049 12.7 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Tubulin_C PF03953.12 ETS60252.1 - 0.25 11.3 0.0 0.65 10.0 0.0 1.7 1 0 0 1 1 1 0 Tubulin C-terminal domain ERCC4 PF02732.10 ETS60253.1 - 3.5e-26 91.6 0.1 5.6e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 ETS60253.1 - 3.9e-06 26.9 0.0 1.8e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cytochrom_C1 PF02167.10 ETS60254.1 - 8.5e-85 283.8 0.0 1.1e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 ETS60254.1 - 0.00091 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 ETS60254.1 - 0.066 14.0 0.0 0.21 12.4 0.0 2.0 1 0 0 1 1 1 0 Cytochrome c Ribosomal_S19 PF00203.16 ETS60255.1 - 6.4e-30 102.6 0.2 1.1e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L18p PF00861.17 ETS60256.1 - 1e-41 141.8 0.2 3.4e-41 140.1 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 ETS60256.1 - 2.7e-31 107.9 3.9 6.3e-31 106.7 2.7 1.7 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L15e PF00827.12 ETS60257.1 - 2.6e-83 278.2 13.8 1.8e-76 255.9 7.7 2.1 2 0 0 2 2 2 2 Ribosomal L15 EAP30 PF04157.11 ETS60258.1 - 2.8e-48 164.0 0.0 3.1e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family TB2_DP1_HVA22 PF03134.14 ETS60259.1 - 1.7e-27 94.9 10.0 2.7e-27 94.3 6.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Zn_clus PF00172.13 ETS60260.1 - 7.2e-07 29.0 6.1 0.00082 19.2 0.6 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BBP1_C PF15272.1 ETS60260.1 - 0.3 10.5 0.0 0.61 9.6 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Foie-gras_1 PF11817.3 ETS60262.1 - 2.4e-33 115.6 0.0 1.8e-32 112.8 0.0 2.5 3 1 0 3 3 3 1 Foie gras liver health family 1 PRCC PF10253.4 ETS60263.1 - 3.2e-05 24.7 5.5 3.2e-05 24.7 3.8 3.9 2 2 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_S10 PF00450.17 ETS60264.1 - 2.7e-106 356.2 0.0 3.3e-106 355.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS60264.1 - 3.9e-06 26.9 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family PI-PLC-X PF00388.14 ETS60267.1 - 1.2e-10 41.0 0.0 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain YL1_C PF08265.6 ETS60268.1 - 1.8e-14 52.9 0.4 1.8e-14 52.9 0.3 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain CENP-B_dimeris PF09026.5 ETS60268.1 - 0.046 13.9 0.8 0.082 13.1 0.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PhageP22-tail PF09251.5 ETS60268.1 - 0.089 11.0 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike Prefoldin_2 PF01920.15 ETS60271.1 - 8e-19 67.3 3.6 1.1e-18 66.9 2.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit GvpK PF05121.7 ETS60271.1 - 0.00049 19.8 0.6 0.00049 19.8 0.4 2.0 1 1 1 2 2 2 1 Gas vesicle protein K Prefoldin PF02996.12 ETS60271.1 - 0.0022 17.6 2.0 0.0034 16.9 1.4 1.4 1 1 0 1 1 1 1 Prefoldin subunit CAP_assoc_N PF14504.1 ETS60271.1 - 0.031 13.9 0.1 0.057 13.1 0.0 1.4 1 1 0 1 1 1 0 CAP-associated N-terminal Effector_1 PF04518.7 ETS60271.1 - 0.075 12.0 1.2 0.095 11.6 0.5 1.4 1 1 0 1 1 1 0 Effector from type III secretion system DivIC PF04977.10 ETS60271.1 - 0.31 10.5 5.7 2.5 7.6 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF2746 PF10874.3 ETS60271.1 - 0.46 10.7 3.5 0.57 10.3 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2746) Fib_alpha PF08702.5 ETS60271.1 - 0.52 10.4 2.5 1.2 9.2 1.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF465 PF04325.8 ETS60271.1 - 1.9 8.2 7.2 0.93 9.2 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Glyco_trans_1_4 PF13692.1 ETS60272.1 - 3.9e-18 65.9 0.2 2.8e-15 56.6 0.0 3.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 ETS60272.1 - 1.3e-10 41.6 10.6 1.3e-10 41.6 7.4 3.1 1 1 2 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 ETS60272.1 - 0.00016 21.9 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 ETS60272.1 - 0.0097 15.3 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1992 PF09350.5 ETS60273.1 - 1e-20 73.2 0.1 3.7e-20 71.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Dynein_light PF01221.13 ETS60274.1 - 2.4e-37 126.7 0.3 2.9e-37 126.5 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 ETS60274.1 - 0.058 12.9 0.1 0.081 12.4 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 28 Suc_Fer-like PF06999.7 ETS60276.1 - 2.2e-24 86.7 0.0 4.4e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Radical_SAM PF04055.16 ETS60276.1 - 6.6e-13 49.1 0.0 1.3e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LRR_9 PF14580.1 ETS60277.1 - 8.5e-53 178.5 0.2 1.2e-52 178.0 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 ETS60277.1 - 4.1e-13 48.8 9.4 4.4e-08 32.7 0.8 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 ETS60277.1 - 7.7e-13 47.7 8.8 2.9e-07 29.9 0.4 4.0 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 ETS60277.1 - 0.0021 17.9 3.3 10 6.5 0.0 4.2 3 2 1 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 ETS60277.1 - 0.25 11.5 4.3 1.1e+02 3.4 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat MFS_1 PF07690.11 ETS60278.1 - 2.8e-19 69.0 37.5 2.8e-19 69.0 26.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CRAL_TRIO_2 PF13716.1 ETS60279.1 - 1.2e-33 116.1 0.0 2.1e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 ETS60279.1 - 9.3e-25 87.0 0.0 2.2e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain WD40 PF00400.27 ETS60280.1 - 2.2e-62 204.8 24.1 1.1e-12 47.2 1.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA PF00004.24 ETS60280.1 - 2.6e-49 166.7 0.0 3.2e-41 140.6 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS60280.1 - 3.2e-07 30.5 5.8 4.4e-05 23.5 0.0 4.2 3 1 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.12 ETS60280.1 - 2.6e-05 23.7 0.0 5.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 ETS60280.1 - 5.8e-05 23.0 0.0 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 ETS60280.1 - 0.00029 20.7 0.7 0.04 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS60280.1 - 0.00048 19.8 0.2 0.0062 16.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 ETS60280.1 - 0.00099 18.8 0.0 0.0073 16.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS60280.1 - 0.0011 19.0 0.1 0.05 13.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 ETS60280.1 - 0.0027 18.0 0.0 0.08 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS60280.1 - 0.0036 18.1 0.1 0.051 14.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 ETS60280.1 - 0.031 14.3 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Apc4_WD40 PF12894.2 ETS60280.1 - 0.04 13.4 0.0 0.89 9.1 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TIP49 PF06068.8 ETS60280.1 - 0.076 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 ETS60280.1 - 0.083 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 ETS60280.1 - 0.088 12.2 0.0 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 ETS60280.1 - 0.11 11.6 0.1 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.6 ETS60280.1 - 0.23 11.3 0.0 0.56 10.1 0.0 1.6 1 0 0 1 1 1 0 Torsin FGGY_N PF00370.16 ETS60281.1 - 2.5e-72 243.1 0.3 3.3e-72 242.7 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 ETS60281.1 - 9.2e-64 214.7 1.8 2.1e-63 213.5 0.8 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain NRDE PF05742.7 ETS60282.1 - 2.4e-30 105.7 0.0 6.1e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 NRDE protein TFIIS_C PF01096.13 ETS60282.1 - 5.1e-10 38.8 0.1 5.1e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 ETS60282.1 - 6.7e-09 35.2 2.3 6.7e-09 35.2 1.6 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 ETS60282.1 - 0.25 11.1 4.0 4.7 7.0 1.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 ETS60282.1 - 3.4 7.5 6.4 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon PHD PF00628.24 ETS60282.1 - 4.8 6.9 8.4 0.24 11.1 1.7 1.9 2 0 0 2 2 2 0 PHD-finger Ribosomal_S19e PF01090.14 ETS60283.1 - 3.4e-55 185.3 0.0 4.1e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e 4HBT PF03061.17 ETS60284.1 - 5.3e-10 39.2 0.1 9.8e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 ETS60284.1 - 0.054 13.4 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DHDPS PF00701.17 ETS60285.1 - 1.7e-42 145.0 0.0 1.9e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ParA PF10609.4 ETS60286.1 - 2.5e-30 104.1 0.0 4e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETS60286.1 - 9.8e-18 64.2 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETS60286.1 - 1.7e-07 31.3 0.0 2.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 ETS60286.1 - 7.5e-05 21.9 1.5 0.0004 19.5 0.3 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 ETS60286.1 - 0.0001 21.5 0.1 0.00092 18.3 0.0 2.2 1 1 1 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 ETS60286.1 - 0.00045 19.8 0.7 0.004 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS60286.1 - 0.0005 19.5 0.0 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 ETS60286.1 - 0.0011 18.2 0.1 0.039 13.1 0.0 2.3 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DNA_ligase_A_N PF04675.9 ETS60287.1 - 1.2e-36 126.1 0.0 2.3e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 ETS60287.1 - 6.9e-34 116.9 0.0 5.2e-26 91.2 0.0 3.5 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 ETS60287.1 - 1.4e-17 63.8 0.0 5.5e-17 61.9 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Esterase_phd PF10503.4 ETS60289.1 - 1.6e-15 56.9 0.3 1.6e-15 56.9 0.2 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 ETS60289.1 - 2.6e-14 52.9 1.6 5.7e-14 51.8 1.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS60289.1 - 3.6e-06 26.7 0.3 7.2e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS60289.1 - 1.1e-05 25.4 2.1 0.00013 21.9 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS60289.1 - 0.0016 17.9 0.2 0.0031 16.9 0.2 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 ETS60289.1 - 0.0076 15.8 1.0 0.036 13.6 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_6 PF13344.1 ETS60294.1 - 1e-22 79.9 0.0 1.7e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS60294.1 - 1.9e-18 65.8 0.0 4.8e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like DUF829 PF05705.9 ETS60295.1 - 2.2e-23 83.2 0.0 9.8e-18 64.7 0.0 3.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.11 ETS60296.1 - 7.7e-25 87.3 46.2 7.7e-25 87.3 32.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 ETS60297.1 - 2.2e-33 113.7 0.0 4.7e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60297.1 - 9.6e-20 70.1 0.0 4.2e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60297.1 - 1.2e-18 66.8 0.0 4.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 ETS60297.1 - 0.00028 20.6 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 ETS60297.1 - 0.095 12.2 0.1 2.3 7.8 0.0 2.5 3 0 0 3 3 3 0 Ribonuclease B OB domain WWbp PF10349.4 ETS60297.1 - 9.8 7.0 24.7 18 6.2 17.1 1.4 1 0 0 1 1 1 0 WW-domain ligand protein Rab5ip PF07019.7 ETS60298.1 - 2.2e-11 43.7 3.0 4.2e-08 33.2 0.1 2.1 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) DUF3099 PF11298.3 ETS60298.1 - 4 7.2 5.1 0.7 9.6 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) Shugoshin_C PF07557.6 ETS60299.1 - 3.9e-08 32.6 3.1 3.9e-08 32.6 2.1 3.2 3 1 1 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.6 ETS60299.1 - 2.4e-05 23.9 1.2 4.5e-05 23.0 0.8 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Myb_DNA-bind_2 PF08914.6 ETS60300.1 - 0.0017 18.1 0.7 0.28 10.9 0.0 2.7 2 0 0 2 2 2 2 Rap1 Myb domain Rap1-DNA-bind PF09197.5 ETS60300.1 - 0.38 11.3 10.3 0.07 13.6 0.5 3.0 2 0 0 2 2 2 0 Rap1, DNA-binding ECR1_N PF14382.1 ETS60301.1 - 3.2e-05 23.1 0.0 5.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 ETS60301.1 - 0.039 13.9 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 RXT2_N PF08595.6 ETS60301.1 - 0.08 12.7 0.3 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal ABC_tran PF00005.22 ETS60302.1 - 3.1e-49 166.7 0.1 4.2e-29 101.5 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 ETS60302.1 - 1.6e-46 158.9 16.3 3.8e-24 85.5 5.9 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 ETS60302.1 - 3.3e-08 33.8 1.5 0.01 15.7 0.1 4.2 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 ETS60302.1 - 3.8e-08 33.4 0.4 0.0031 17.3 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_29 PF13555.1 ETS60302.1 - 3.8e-08 32.7 0.3 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS60302.1 - 7.3e-08 32.6 18.1 7.4e-05 22.8 0.8 4.7 3 1 1 4 4 4 2 AAA ATPase domain AAA_10 PF12846.2 ETS60302.1 - 8.3e-08 32.0 1.7 0.0016 17.9 0.1 3.3 2 1 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 ETS60302.1 - 2.8e-07 29.9 7.4 0.017 14.3 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS60302.1 - 3.1e-07 30.9 1.6 0.00012 22.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 ETS60302.1 - 4.2e-07 29.5 0.0 0.012 15.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 ETS60302.1 - 7.2e-05 22.7 0.1 0.21 11.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 ETS60302.1 - 0.00016 22.4 0.0 0.23 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 ETS60302.1 - 0.00018 20.2 0.1 0.22 10.0 0.0 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 ETS60302.1 - 0.00024 20.7 0.9 0.5 9.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 ETS60302.1 - 0.00035 19.5 0.0 0.052 12.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETS60302.1 - 0.00041 20.5 0.7 7.1 6.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 ETS60302.1 - 0.00071 20.0 0.6 1.5 9.3 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 ETS60302.1 - 0.0013 18.4 0.1 2.1 8.0 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 ETS60302.1 - 0.0019 17.4 0.0 0.54 9.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 ETS60302.1 - 0.0026 17.6 1.9 0.035 14.0 0.3 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 ETS60302.1 - 0.0029 17.1 0.0 0.92 8.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 ETS60302.1 - 0.0034 17.1 0.0 0.43 10.2 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase NACHT PF05729.7 ETS60302.1 - 0.0034 17.0 0.3 1.6 8.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 ETS60302.1 - 0.0065 15.5 0.4 1 8.4 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 ETS60302.1 - 0.0073 16.6 0.0 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS60302.1 - 0.0075 15.9 5.2 0.48 10.2 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain CbiA PF01656.18 ETS60302.1 - 0.015 14.7 0.1 0.077 12.3 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 ETS60302.1 - 0.017 15.3 0.1 9.9 6.3 0.0 3.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETS60302.1 - 0.02 13.8 0.0 6.3 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 ETS60302.1 - 0.025 14.7 0.1 14 5.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 ETS60302.1 - 0.031 14.1 1.9 1.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Dynamin family Telomerase_RBD PF12009.3 ETS60302.1 - 0.071 13.0 0.6 0.21 11.4 0.4 1.8 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain PduV-EutP PF10662.4 ETS60302.1 - 0.082 12.3 0.1 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 ETS60302.1 - 0.095 12.4 0.1 27 4.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS60302.1 - 0.11 12.3 0.0 4.1 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 ETS60302.1 - 0.14 11.6 0.1 0.91 8.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 ETS60302.1 - 0.34 10.4 0.2 20 4.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.18 ETS60303.1 - 6.2e-25 87.2 0.8 1e-24 86.5 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS60303.1 - 1.2e-09 37.8 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3945 PF13101.1 ETS60303.1 - 0.13 11.5 0.0 0.88 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) mRNA_triPase PF02940.10 ETS60304.1 - 2.1e-51 174.7 0.1 2.6e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Big_1 PF02369.11 ETS60304.1 - 0.022 14.6 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DEAD PF00270.24 ETS60305.1 - 6.2e-17 61.5 0.0 5.7e-16 58.4 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS60305.1 - 1.8e-16 59.7 0.0 1e-14 54.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS60305.1 - 0.003 17.4 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RPE65 PF03055.10 ETS60306.1 - 5.9e-120 401.0 0.1 7e-120 400.8 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FAD_binding_4 PF01565.18 ETS60307.1 - 4e-24 84.6 0.0 6.5e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N PF00107.21 ETS60308.1 - 3.2e-14 52.5 0.0 7.1e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS60308.1 - 9.5e-14 52.3 0.0 3.9e-13 50.4 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS60308.1 - 2.8e-05 23.8 0.1 9.5e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FA_hydroxylase PF04116.8 ETS60309.1 - 2.5e-12 47.2 17.2 2.5e-12 47.2 11.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PALP PF00291.20 ETS60310.1 - 5.9e-45 153.8 1.4 7.4e-45 153.4 0.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.20 ETS60311.1 - 1.8e-18 67.0 0.7 1.8e-18 67.0 0.5 1.7 2 0 0 2 2 2 1 short chain dehydrogenase M20_dimer PF07687.9 ETS60311.1 - 5.3e-11 42.2 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain KR PF08659.5 ETS60311.1 - 2.4e-09 37.1 0.6 5e-09 36.0 0.4 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS60311.1 - 6.8e-06 26.0 0.1 1.1e-05 25.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 ETS60311.1 - 4.2e-05 22.5 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 ETS60311.1 - 0.00017 20.6 0.2 0.00022 20.2 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MHCassoc_trimer PF08831.5 ETS60311.1 - 0.00025 20.8 0.5 0.00057 19.6 0.3 1.5 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain Epimerase PF01370.16 ETS60311.1 - 0.00083 18.8 0.1 0.0035 16.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS60311.1 - 0.00093 17.9 0.4 0.0013 17.4 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS60311.1 - 0.012 15.5 1.2 0.042 13.8 0.8 1.8 1 1 0 1 1 1 0 NADH(P)-binding Peripla_BP_6 PF13458.1 ETS60311.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Fungal_trans PF04082.13 ETS60312.1 - 2.1e-24 85.8 0.0 3.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS60312.1 - 7.5e-07 28.9 10.7 7.5e-07 28.9 7.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.17 ETS60313.1 - 1.8e-40 138.3 0.0 2.1e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AstB PF04996.7 ETS60314.1 - 0.032 13.0 0.3 0.032 13.0 0.2 1.5 2 0 0 2 2 2 0 Succinylarginine dihydrolase Mad3_BUB1_I PF08311.7 ETS60315.1 - 2.9e-36 124.0 0.1 4.8e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 ETS60315.1 - 2.2e-13 49.9 0.0 3.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PBP1_TM PF14812.1 ETS60315.1 - 5.4 7.3 43.6 0.22 11.8 3.2 6.8 6 0 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PEHE PF15275.1 ETS60316.1 - 0.00026 21.4 4.0 0.00026 21.4 2.8 4.6 4 1 2 6 6 6 1 PEHE domain SAS4 PF15460.1 ETS60316.1 - 0.004 17.0 2.3 0.01 15.6 1.6 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 EF-hand_1 PF00036.27 ETS60317.1 - 1.3e-22 77.3 0.0 1.3e-05 24.1 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETS60317.1 - 2.1e-18 64.5 0.0 3.7e-06 26.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 ETS60317.1 - 4.9e-17 61.8 0.0 6.8e-08 32.5 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETS60317.1 - 6e-17 60.1 0.0 0.00061 19.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 ETS60317.1 - 3.4e-15 55.3 0.4 2e-08 33.7 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair Toprim_2 PF13155.1 ETS60317.1 - 0.14 12.4 0.0 28 5.1 0.0 2.7 1 1 2 3 3 3 0 Toprim-like Extensin_2 PF04554.8 ETS60317.1 - 2.9 7.8 18.7 1.5 8.7 7.8 2.2 1 1 1 2 2 2 0 Extensin-like region Cation_efflux PF01545.16 ETS60318.1 - 1.2e-58 198.4 6.7 1.2e-58 198.4 4.6 3.1 3 0 0 3 3 3 2 Cation efflux family DUF92 PF01940.11 ETS60319.1 - 2.5e-51 174.0 12.1 4.3e-51 173.2 8.4 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF92 COG6 PF06419.6 ETS60320.1 - 2e-117 392.9 0.0 1.4e-116 390.1 0.0 1.8 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 BT1 PF03092.11 ETS60320.1 - 0.19 10.4 0.2 0.29 9.7 0.1 1.2 1 0 0 1 1 1 0 BT1 family Ribosomal_S11 PF00411.14 ETS60321.1 - 1.6e-11 44.3 0.5 3.2e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 Glyco_hydro_17 PF00332.13 ETS60322.1 - 1.5e-12 47.2 0.9 3.6e-09 36.1 0.1 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 Wzz PF02706.10 ETS60322.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Chain length determinant protein LRR19-TM PF15176.1 ETS60322.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Pro-kuma_activ PF09286.6 ETS60323.1 - 1.2e-33 116.1 0.1 2.7e-33 114.9 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS60323.1 - 2.6e-08 33.3 1.4 4.1e-08 32.7 1.0 1.2 1 0 0 1 1 1 1 Subtilase family PAE PF03283.8 ETS60324.1 - 5.8e-17 61.3 0.2 1.1e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 Pectinacetylesterase DUF4091 PF13320.1 ETS60324.1 - 0.0067 16.3 0.3 0.029 14.2 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4091) DNA_pol_viral_N PF00242.12 ETS60324.1 - 1.6 7.6 10.9 2.5 7.0 7.6 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PAN_3 PF08277.7 ETS60324.1 - 1.7 8.3 5.6 0.36 10.4 0.8 2.2 2 0 0 2 2 2 0 PAN-like domain Macoilin PF09726.4 ETS60324.1 - 8 4.6 14.0 12 3.9 9.7 1.2 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 ETS60324.1 - 9.4 4.7 20.3 13 4.2 14.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein UCR_UQCRX_QCR9 PF05365.7 ETS60327.1 - 3.4e-21 74.6 7.7 3.7e-20 71.2 1.7 2.1 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RNase_HII PF01351.13 ETS60330.1 - 4.9e-43 147.0 0.0 4.2e-39 134.2 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII DNA_pol_A_exo1 PF01612.15 ETS60331.1 - 6.2e-41 139.7 0.8 8.8e-41 139.2 0.2 1.5 2 0 0 2 2 2 1 3'-5' exonuclease HRDC PF00570.18 ETS60331.1 - 7.2e-13 48.0 0.4 1.9e-12 46.6 0.3 1.8 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 ETS60331.1 - 2.1e-12 47.1 6.1 9.4e-07 29.0 0.1 3.5 2 1 1 3 3 3 2 PMC2NT (NUC016) domain DUF2718 PF10918.3 ETS60331.1 - 9.6 6.2 5.5 20 5.2 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) YchF-GTPase_C PF06071.8 ETS60332.1 - 6.6e-33 112.3 1.6 8.8e-33 111.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 ETS60332.1 - 3.4e-14 52.7 0.1 3.8e-13 49.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS60332.1 - 2.5e-05 23.6 0.0 4.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.1 ETS60332.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 T_cell_tran_alt PF15128.1 ETS60333.1 - 0.05 13.0 0.5 0.13 11.7 0.0 1.8 1 1 1 2 2 2 0 T-cell leukemia translocation-altered Cutinase PF01083.17 ETS60334.1 - 1.3e-28 99.9 1.4 2.1e-28 99.2 1.0 1.3 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 ETS60334.1 - 0.026 14.7 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Milton PF12448.3 ETS60334.1 - 0.88 9.7 6.8 1.7 8.7 4.7 1.4 1 0 0 1 1 1 0 Kinesin associated protein Sporozoite_P67 PF05642.6 ETS60334.1 - 1.5 6.5 17.0 2.2 6.0 11.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Consortin_C PF15281.1 ETS60335.1 - 0.92 9.0 3.9 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 Consortin C-terminus UDPG_MGDP_dh_N PF03721.9 ETS60336.1 - 8.1e-22 77.5 0.0 2e-20 72.9 0.0 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 ETS60336.1 - 1.5e-18 66.8 0.1 1.1e-17 64.0 0.0 2.5 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 ETS60336.1 - 6.5e-05 23.0 0.1 0.00032 20.8 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_18 PF12847.2 ETS60336.1 - 0.00051 20.5 0.0 0.0024 18.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_2 PF03446.10 ETS60336.1 - 0.00091 19.1 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 ETS60336.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_31 PF13847.1 ETS60336.1 - 0.0045 16.5 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60336.1 - 0.0058 17.1 0.2 0.19 12.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain GFO_IDH_MocA PF01408.17 ETS60336.1 - 0.035 14.6 0.1 0.2 12.1 0.0 2.3 3 0 0 3 3 2 0 Oxidoreductase family, NAD-binding Rossmann fold HEM4 PF02602.10 ETS60336.1 - 0.05 12.8 0.4 3 7.0 0.1 2.3 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Methyltransf_26 PF13659.1 ETS60336.1 - 0.056 13.4 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 ETS60336.1 - 0.075 12.1 0.0 2.6 7.1 0.0 2.5 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dynamin_M PF01031.15 ETS60336.1 - 0.087 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region ApbA PF02558.11 ETS60336.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Chitin_synth_2 PF03142.10 ETS60337.1 - 4e-17 61.8 0.1 9e-15 54.0 0.1 2.4 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 ETS60337.1 - 5.3e-06 26.2 4.4 1.1e-05 25.2 3.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS60337.1 - 0.001 18.9 2.5 0.0061 16.3 0.2 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CMV_1a PF12467.3 ETS60337.1 - 1.3 9.3 5.6 3.4 8.0 3.9 1.6 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF768 PF05589.6 ETS60338.1 - 0.0027 17.5 0.1 0.098 12.6 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF768) DUF4031 PF13223.1 ETS60338.1 - 0.01 15.9 0.1 0.12 12.5 0.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF4031) DUF3950 PF13132.1 ETS60338.1 - 0.044 13.3 0.7 12 5.5 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3950) Iso_dh PF00180.15 ETS60339.1 - 5e-71 239.4 0.0 5.8e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Condensation PF00668.15 ETS60339.1 - 0.022 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Condensation domain G-gamma PF00631.17 ETS60341.1 - 2.5e-24 84.7 0.1 8.8e-24 83.0 0.0 2.0 2 0 0 2 2 2 1 GGL domain PNP_UDP_1 PF01048.15 ETS60342.1 - 2.2e-40 138.0 1.2 3.1e-40 137.6 0.9 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily CK_II_beta PF01214.13 ETS60343.1 - 4.7e-72 241.3 0.0 5.9e-72 241.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ras PF00071.17 ETS60345.1 - 3.1e-60 202.2 1.1 4.1e-60 201.8 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS60345.1 - 4.4e-21 75.5 0.3 8.7e-21 74.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS60345.1 - 3.9e-16 58.7 0.2 4.8e-16 58.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS60345.1 - 1.8e-08 34.0 0.2 8.2e-08 31.9 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS60345.1 - 3.2e-06 26.4 0.4 4.1e-06 26.1 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETS60345.1 - 4.2e-06 26.0 0.1 6.4e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 ETS60345.1 - 1.7e-05 24.7 0.1 4.1e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS60345.1 - 0.01 15.1 0.0 0.55 9.5 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 ETS60345.1 - 0.016 15.3 0.0 1.6 8.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 ETS60345.1 - 0.017 14.8 0.3 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 ETS60345.1 - 0.018 14.9 0.1 1.2 9.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 ETS60345.1 - 0.03 14.1 0.2 3.3 7.5 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 ETS60345.1 - 0.097 12.3 0.1 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Cellulase PF00150.13 ETS60346.1 - 2.5e-17 63.0 4.6 3.7e-17 62.4 3.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ThiF PF00899.16 ETS60347.1 - 4.3e-40 136.6 0.0 9.6e-40 135.5 0.0 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 ETS60347.1 - 1.5e-24 85.5 0.0 2.4e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 ETS60347.1 - 7.9e-24 83.0 0.3 1.4e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 ETS60347.1 - 7.9e-19 66.7 2.3 1.7e-18 65.6 1.6 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 ETS60347.1 - 0.00041 19.8 0.4 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 ETS60347.1 - 0.0038 17.3 0.0 0.0069 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 ETS60347.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Gmx_para_CXXCG PF09535.5 ETS60347.1 - 0.12 11.3 0.1 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Pyr_redox PF00070.22 ETS60347.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.2 ETS60348.1 - 0.0018 18.0 0.1 0.0035 17.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS60348.1 - 0.05 13.4 9.7 0.11 12.3 4.3 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS60348.1 - 0.17 11.5 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Nup188 PF10487.4 ETS60349.1 - 9e-14 50.3 0.0 0.00011 20.3 0.0 3.7 4 0 0 4 4 4 3 Nucleoporin subcomplex protein binding to Pom34 Fer4_NifH PF00142.13 ETS60349.1 - 0.42 9.7 0.0 0.66 9.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family IncA PF04156.9 ETS60350.1 - 0.036 13.6 0.1 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 IncA protein KAR9 PF08580.5 ETS60350.1 - 0.33 9.1 13.6 0.46 8.7 9.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Nuc_sug_transp PF04142.10 ETS60352.1 - 3.6e-68 229.2 0.5 7.9e-68 228.1 0.3 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 ETS60352.1 - 1.5e-08 33.9 9.6 3.3e-05 22.9 0.5 2.3 2 0 0 2 2 2 2 UAA transporter family EmrE PF13536.1 ETS60352.1 - 1.8e-05 24.9 1.8 1.8e-05 24.9 1.3 3.1 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 ETS60352.1 - 4e-05 23.3 16.4 0.0033 17.0 0.2 3.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 ETS60352.1 - 0.00022 21.2 2.0 0.00022 21.2 1.4 2.8 2 1 0 2 2 2 1 EamA-like transporter family DUF2417 PF10329.4 ETS60353.1 - 3e-12 46.4 0.1 5.8e-12 45.5 0.1 1.5 1 1 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 ETS60353.1 - 6e-05 23.0 0.6 0.00012 22.0 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cytochrom_B_N PF00033.14 ETS60353.1 - 0.038 13.3 5.7 0.22 10.8 3.9 2.1 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1270 PF06900.6 ETS60353.1 - 0.32 11.1 4.2 0.82 9.8 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) RRM_1 PF00076.17 ETS60354.1 - 8.1e-12 44.6 0.0 1.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60354.1 - 8.4e-11 41.6 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 ETS60354.1 - 0.00084 18.2 33.2 0.00084 18.2 23.0 2.8 1 1 0 2 2 2 1 Plant specific eukaryotic initiation factor 4B RRM_5 PF13893.1 ETS60354.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 ETS60354.1 - 0.25 10.8 19.2 0.44 9.9 13.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Metaviral_G PF09595.5 ETS60354.1 - 1.6 8.3 11.0 3.4 7.2 7.6 1.5 1 0 0 1 1 1 0 Metaviral_G glycoprotein SPC25 PF06703.6 ETS60355.1 - 2.5e-41 140.9 0.0 3e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_transf_22 PF03901.12 ETS60356.1 - 5e-66 223.4 17.3 1.7e-64 218.3 11.0 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family AAA PF00004.24 ETS60357.1 - 1.5e-13 51.1 0.0 3.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS60357.1 - 5.4e-10 39.5 0.0 5.2e-09 36.3 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS60357.1 - 4.5e-07 30.0 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS60357.1 - 2.5e-05 23.9 0.4 0.00021 20.9 0.0 2.9 4 0 0 4 4 4 1 Part of AAA domain AAA_11 PF13086.1 ETS60357.1 - 0.0073 15.9 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 ETS60357.1 - 0.009 14.9 0.0 0.075 11.9 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase NACHT PF05729.7 ETS60357.1 - 0.019 14.6 0.0 0.053 13.1 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Cdc6_C PF09079.6 ETS60357.1 - 0.11 12.2 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 CDC6, C terminal DUF2075 PF09848.4 ETS60357.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BCDHK_Adom3 PF10436.4 ETS60358.1 - 3.1e-46 156.8 0.0 4.6e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 ETS60358.1 - 3.9e-13 49.0 0.0 1.2e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETS60358.1 - 1.5e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Grp1_Fun34_YaaH PF01184.14 ETS60359.1 - 1.2e-68 230.5 18.0 1.4e-68 230.2 12.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pyridoxal_deC PF00282.14 ETS60360.1 - 1.5e-104 349.4 0.0 5.1e-67 225.9 0.0 2.1 1 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Grp1_Fun34_YaaH PF01184.14 ETS60360.1 - 4.3e-13 49.0 15.9 7.4e-13 48.2 11.1 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aminotran_1_2 PF00155.16 ETS60360.1 - 0.0021 17.1 0.0 0.92 8.3 0.0 2.7 3 0 0 3 3 3 2 Aminotransferase class I and II NIPSNAP PF07978.8 ETS60361.1 - 5.9e-37 125.7 2.3 4.1e-27 94.1 0.2 2.3 2 0 0 2 2 2 2 NIPSNAP Pribosyltran_N PF13793.1 ETS60362.1 - 7.2e-46 154.6 0.2 2.6e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 ETS60362.1 - 1.2e-38 132.7 3.8 4.5e-32 111.2 0.2 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 ETS60362.1 - 1.2e-11 44.3 1.8 4.6e-11 42.5 0.3 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETS60362.1 - 0.064 12.4 0.1 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase FAD_binding_7 PF03441.9 ETS60363.1 - 2.4e-90 302.4 0.1 3.9e-90 301.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS60363.1 - 8.7e-42 142.6 0.0 1.8e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Glyco_hydro_17 PF00332.13 ETS60364.1 - 6.8e-07 28.6 0.9 1.5e-06 27.4 0.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Gypsy PF07253.6 ETS60364.1 - 0.074 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein DUF1043 PF06295.7 ETS60364.1 - 0.17 11.5 1.4 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) SecE PF00584.15 ETS60364.1 - 0.37 10.4 3.7 0.16 11.5 0.4 1.9 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex EphA2_TM PF14575.1 ETS60364.1 - 0.39 11.1 0.1 0.39 11.1 0.1 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 ETS60364.1 - 0.47 10.6 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Glyco_hydro_76 PF03663.9 ETS60365.1 - 6.5e-50 170.5 7.8 8e-50 170.2 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS60365.1 - 0.0093 15.0 1.5 1.2 8.1 0.0 2.7 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 ETS60365.1 - 0.025 13.8 0.1 0.43 9.8 0.0 2.4 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Sda PF08970.5 ETS60365.1 - 0.037 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A Glyco_hydro_47 PF01532.15 ETS60365.1 - 0.058 12.0 0.1 0.62 8.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 Sugar_tr PF00083.19 ETS60367.1 - 3.8e-108 361.9 25.3 6.3e-108 361.2 17.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS60367.1 - 4.9e-28 97.8 69.7 5.1e-25 87.9 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS60367.1 - 0.0091 15.7 0.9 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 MFS_1 like family Glyco_hydro_3 PF00933.16 ETS60369.1 - 3.3e-78 262.6 0.0 5.3e-78 262.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS60369.1 - 1.7e-47 161.8 0.0 2e-46 158.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS60369.1 - 4.1e-24 84.3 0.2 8.5e-24 83.2 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain OTU PF02338.14 ETS60370.1 - 3.4e-09 37.3 0.0 5.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 ETS60370.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) COesterase PF00135.23 ETS60371.1 - 1.3e-87 294.7 0.0 1.7e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS60371.1 - 2.6e-10 40.2 2.2 0.00045 19.8 0.3 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pyrophosphatase PF00719.14 ETS60372.1 - 1.4e-52 177.2 0.2 1.9e-52 176.8 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Nol1_Nop2_Fmu PF01189.12 ETS60373.1 - 2e-16 60.2 0.2 4.1e-15 55.9 0.1 2.7 1 1 0 1 1 1 1 NOL1/NOP2/sun family Cathelicidins PF00666.12 ETS60373.1 - 0.027 14.6 0.1 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Cathelicidin Cpn60_TCP1 PF00118.19 ETS60375.1 - 3.6e-157 523.8 1.3 4.1e-157 523.7 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MTHFR PF02219.12 ETS60376.1 - 4.2e-103 344.3 0.0 1.4e-84 283.5 0.0 2.1 1 1 1 2 2 2 2 Methylenetetrahydrofolate reductase DUF2195 PF09961.4 ETS60377.1 - 0.034 13.9 0.5 0.074 12.8 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) Pyridoxal_deC PF00282.14 ETS60378.1 - 2.5e-63 213.7 0.0 3.3e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 ETS60378.1 - 0.0013 17.5 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF1708 PF08101.6 ETS60379.1 - 1.5e-13 50.3 0.0 9.5e-10 37.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 ETS60379.1 - 1.7e-06 27.7 0.0 0.00071 19.2 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain NatB_MDM20 PF09797.4 ETS60380.1 - 5e-74 249.1 0.0 8.5e-74 248.4 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.1 ETS60380.1 - 2.5e-05 24.8 1.6 0.016 15.8 0.0 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 ETS60380.1 - 0.00018 21.7 1.5 0.00018 21.7 1.0 5.3 5 3 0 5 5 5 1 Bacterial transcriptional activator domain TPR_19 PF14559.1 ETS60380.1 - 0.022 15.1 8.3 3.4 8.0 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Chorion_2 PF03964.10 ETS60380.1 - 0.11 13.0 0.8 0.39 11.3 0.0 2.3 2 0 0 2 2 2 0 Chorion family 2 Acyltransferase PF01553.16 ETS60382.1 - 1.2e-21 76.4 0.0 2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PrpF PF04303.8 ETS60383.1 - 1.8e-52 178.3 0.1 3.4e-37 128.0 0.0 2.5 2 1 0 2 2 2 2 PrpF protein Epimerase PF01370.16 ETS60384.1 - 9.3e-42 143.0 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 ETS60384.1 - 1.1e-25 89.3 0.0 1.9e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit RmlD_sub_bind PF04321.12 ETS60384.1 - 1.2e-10 40.8 0.0 2.8e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 ETS60384.1 - 1.3e-10 40.5 0.0 4.4e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS60384.1 - 3.9e-08 32.5 0.0 5.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 ETS60384.1 - 4.1e-07 29.1 0.0 3.2e-06 26.2 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS60384.1 - 4.2e-06 26.7 0.0 7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS60384.1 - 5.6e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS60384.1 - 0.0018 18.2 0.0 0.041 13.8 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding LIM PF00412.17 ETS60385.1 - 4.9e-14 52.1 28.9 1.9e-05 24.5 0.5 6.4 6 0 0 6 6 6 4 LIM domain OrfB_Zn_ribbon PF07282.6 ETS60385.1 - 0.16 11.6 0.1 0.16 11.6 0.1 6.5 7 2 1 8 8 8 0 Putative transposase DNA-binding domain Vps39_2 PF10367.4 ETS60385.1 - 5.8 7.1 9.1 96 3.2 0.3 4.2 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 Ribosomal_L10 PF00466.15 ETS60386.1 - 2.7e-26 91.4 0.0 5.4e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 ETS60386.1 - 9.1e-22 77.2 9.8 8.9e-21 74.0 6.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF1021 PF06257.6 ETS60386.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) TAP42 PF04177.7 ETS60388.1 - 5.4e-79 265.5 0.0 6.6e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family TMEM171 PF15471.1 ETS60388.1 - 0.084 11.6 1.4 0.15 10.7 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 RRXRR PF14239.1 ETS60388.1 - 0.087 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 RRXRR protein DUF3246 PF11596.3 ETS60388.1 - 0.18 11.0 3.5 3.9 6.7 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.1 ETS60388.1 - 0.3 11.4 4.7 7.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldo_ket_red PF00248.16 ETS60389.1 - 1.9e-40 138.5 0.1 2.2e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YflT PF11181.3 ETS60389.1 - 0.013 15.6 0.0 0.043 13.9 0.0 1.9 1 0 0 1 1 1 0 Heat induced stress protein YflT Tox-GHH PF15636.1 ETS60389.1 - 0.075 12.6 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF3128 PF11326.3 ETS60390.1 - 0.00025 21.0 0.3 0.00039 20.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Cmc1 PF08583.5 ETS60390.1 - 0.003 17.3 0.7 0.0049 16.6 0.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 ETS60390.1 - 0.0078 16.1 0.6 0.011 15.7 0.4 1.4 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.4 ETS60390.1 - 0.094 12.7 0.9 0.15 12.0 0.6 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 PADR1 PF08063.7 ETS60390.1 - 0.13 11.6 0.4 3.9 6.9 0.0 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain Glyco_hydro_92 PF07971.7 ETS60391.1 - 7.7e-129 430.5 0.0 1e-128 430.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Seipin PF06775.9 ETS60392.1 - 5.8e-63 212.0 0.0 8.3e-63 211.5 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Peptidase_S51 PF03575.12 ETS60392.1 - 0.065 12.9 0.1 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S51 Pex14_N PF04695.8 ETS60392.1 - 0.16 12.0 9.0 0.52 10.3 6.2 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CTNNB1_binding PF08347.6 ETS60392.1 - 0.56 10.4 12.1 1.4 9.1 1.5 2.5 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Suf PF05843.9 ETS60392.1 - 0.64 9.7 8.0 1 9.0 5.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 ETS60392.1 - 4 6.7 9.0 7.5 5.8 6.2 1.3 1 0 0 1 1 1 0 Spt20 family Flavin_Reduct PF01613.13 ETS60394.1 - 1.7e-31 109.1 0.3 2.6e-31 108.5 0.2 1.3 1 0 0 1 1 1 1 Flavin reductase like domain GP40 PF11025.3 ETS60394.1 - 0.046 13.2 0.2 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Amidohydro_1 PF01979.15 ETS60395.1 - 2.2e-58 198.5 0.8 3.4e-58 197.8 0.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 ETS60395.1 - 6e-56 187.8 0.3 1.2e-55 186.8 0.2 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 ETS60395.1 - 2.1e-39 133.5 1.2 3.2e-39 132.9 0.2 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.15 ETS60395.1 - 8.7e-34 115.3 0.0 2.7e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.6 ETS60395.1 - 7.8e-06 25.3 0.3 7.1e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS60395.1 - 7e-05 22.5 2.8 7e-05 22.5 1.9 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 ETS60395.1 - 0.0027 17.8 8.1 0.053 13.5 0.2 3.5 4 1 0 4 4 4 2 Amidohydrolase Amidase PF01425.16 ETS60397.1 - 3.4e-44 151.4 0.3 6.4e-42 143.9 0.1 2.1 2 0 0 2 2 2 2 Amidase DIOX_N PF14226.1 ETS60398.1 - 9.5e-11 42.2 0.0 2.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS60398.1 - 3.2e-09 36.9 0.1 7.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.1 ETS60399.1 - 0.00071 19.3 0.0 0.0018 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS60399.1 - 0.038 14.5 0.0 0.78 10.3 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 ETS60399.1 - 0.091 13.1 0.0 0.32 11.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain YL1 PF05764.8 ETS60400.1 - 1.3e-48 165.7 18.9 1.3e-48 165.7 13.1 2.4 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 ETS60400.1 - 2.4e-14 52.5 0.5 4e-14 51.8 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain cwf18 PF08315.7 ETS60401.1 - 6.4e-26 91.3 7.3 9.6e-26 90.7 5.1 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor GATase_2 PF00310.16 ETS60402.1 - 4.8e-25 88.0 0.1 4.6e-20 71.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 ETS60402.1 - 2.3e-15 56.7 0.0 8.4e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 ETS60402.1 - 1.5e-13 50.5 0.3 8.3e-13 48.1 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 ETS60402.1 - 2.8e-12 46.4 0.0 5.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 ETS60402.1 - 2.7e-07 29.5 0.0 7.3e-07 28.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Ribosomal_60s PF00428.14 ETS60402.1 - 0.83 10.0 4.6 2.5 8.5 3.2 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_M24 PF00557.19 ETS60403.1 - 2.8e-42 144.6 0.4 3.6e-42 144.3 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TFIIF_alpha PF05793.7 ETS60403.1 - 0.0022 16.4 11.1 0.0031 15.9 7.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETS60403.1 - 0.014 13.3 9.3 0.021 12.8 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 ETS60403.1 - 0.019 13.9 6.9 0.036 13.0 4.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YL1 PF05764.8 ETS60403.1 - 0.026 14.1 9.4 0.041 13.4 6.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 ETS60403.1 - 0.045 13.0 10.2 0.063 12.5 7.0 1.1 1 0 0 1 1 1 0 SDA1 BAF1_ABF1 PF04684.8 ETS60403.1 - 0.1 11.4 15.7 0.032 13.0 7.2 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CDC45 PF02724.9 ETS60403.1 - 0.28 9.1 7.3 0.38 8.7 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 ETS60403.1 - 0.36 10.4 8.8 0.85 9.2 6.1 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETS60403.1 - 1 8.8 10.5 2.1 7.8 7.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Cnd2 PF05786.9 ETS60403.1 - 1.5 7.2 13.5 2.3 6.6 9.4 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 CENP-B_dimeris PF09026.5 ETS60403.1 - 3.3 7.9 12.2 7.9 6.7 8.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HSP90 PF00183.13 ETS60403.1 - 3.4 5.9 9.2 7.8 4.7 6.5 1.4 2 0 0 2 2 2 0 Hsp90 protein Tom37_C PF11801.3 ETS60403.1 - 3.6 7.4 5.6 2.7 7.8 2.0 1.9 2 0 0 2 2 2 0 Tom37 C-terminal domain Macro PF01661.16 ETS60404.1 - 9.2e-42 141.6 0.2 1.4e-41 141.1 0.1 1.3 1 0 0 1 1 1 1 Macro domain Romo1 PF10247.4 ETS60405.1 - 8.3e-25 86.7 8.9 1.1e-24 86.3 6.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 zf-HC5HC2H_2 PF13832.1 ETS60406.1 - 7.4e-34 116.0 6.4 7.4e-34 116.0 4.4 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETS60406.1 - 4.8e-25 87.5 4.2 4.8e-25 87.5 2.9 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 ETS60406.1 - 1.6e-23 83.7 0.3 1.6e-23 83.7 0.2 3.7 4 0 0 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.20 ETS60406.1 - 1.9e-18 66.1 0.5 4e-18 65.1 0.3 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 ETS60406.1 - 1e-14 53.5 2.6 1e-14 53.5 1.8 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.12 ETS60406.1 - 9.3e-11 41.7 0.1 3.1e-10 40.1 0.1 2.0 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 ETS60406.1 - 3e-10 39.6 21.1 4e-10 39.2 4.0 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 ETS60406.1 - 0.0013 18.6 14.3 0.0065 16.4 3.3 2.6 2 0 0 2 2 2 2 RING-like domain zf-PHD-like PF15446.1 ETS60406.1 - 0.0045 16.2 0.9 0.0045 16.2 0.6 2.5 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 ETS60406.1 - 0.013 15.1 0.4 0.013 15.1 0.3 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TMEM171 PF15471.1 ETS60406.1 - 4 6.1 5.4 10 4.7 3.7 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 Use1 PF09753.4 ETS60407.1 - 2e-10 40.5 0.1 3.8e-10 39.6 0.1 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 K_channel_TID PF07941.6 ETS60407.1 - 4 7.7 7.2 0.77 10.0 1.7 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain tRNA-synt_His PF13393.1 ETS60408.1 - 5.4e-42 143.9 0.1 3.6e-36 124.7 0.0 3.0 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 ETS60408.1 - 1.5e-17 63.7 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS60408.1 - 1.4e-08 34.5 0.2 4.3e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 ETS60408.1 - 0.00021 20.1 0.3 0.083 11.6 0.1 3.0 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 ETS60408.1 - 0.0016 17.6 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Ribosomal_60s PF00428.14 ETS60408.1 - 0.013 15.9 0.8 0.013 15.9 0.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein APG6 PF04111.7 ETS60408.1 - 0.071 12.1 0.4 0.11 11.4 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ubiquitin PF00240.18 ETS60409.1 - 8.3e-25 85.9 0.3 9.2e-25 85.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETS60409.1 - 6.2e-17 61.0 0.3 6.8e-17 60.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETS60409.1 - 0.00014 22.0 0.1 0.0004 20.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETS60409.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HMG_box PF00505.14 ETS60410.1 - 5.1e-10 39.4 3.6 4e-09 36.6 2.5 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS60410.1 - 0.0077 16.5 1.1 0.016 15.5 0.8 1.5 1 0 0 1 1 1 1 HMG-box domain RibD_C PF01872.12 ETS60411.1 - 9.1e-33 113.5 0.1 1.1e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DAGK_cat PF00781.19 ETS60412.1 - 6e-20 70.9 0.0 1.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain adh_short PF00106.20 ETS60413.1 - 5.9e-15 55.5 0.7 9.4e-14 51.6 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS60413.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 ETS60413.1 - 4.5e-05 22.7 0.0 6.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 ETS60413.1 - 8.6e-05 22.2 1.1 0.00069 19.3 0.8 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS60413.1 - 0.012 15.5 0.4 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 ETS60413.1 - 0.034 13.5 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 ETS60413.1 - 0.084 11.9 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TMEM95 PF15203.1 ETS60413.1 - 0.094 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 TMEM95 family NmrA PF05368.8 ETS60413.1 - 0.11 11.7 0.7 0.21 10.7 0.0 1.8 3 0 0 3 3 3 0 NmrA-like family Pkinase PF00069.20 ETS60414.1 - 3.9e-71 239.2 0.0 4.8e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60414.1 - 5.4e-36 123.9 0.0 6.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60414.1 - 9.8e-09 34.5 0.0 1.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETS60414.1 - 2.1e-05 23.9 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 ETS60414.1 - 2.8e-05 23.2 0.2 7.5e-05 21.8 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS60414.1 - 0.00045 20.0 0.0 0.00099 18.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS60414.1 - 0.045 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 ETS60414.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 ETS60414.1 - 0.1 11.3 0.1 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-RING_2 PF13639.1 ETS60415.1 - 1.8e-12 46.9 10.0 2.8e-12 46.2 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS60415.1 - 5.4e-10 39.2 3.8 9.1e-10 38.5 2.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS60415.1 - 1.6e-06 27.8 3.6 3.5e-06 26.7 2.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 ETS60415.1 - 2.9e-06 27.2 8.0 4.4e-06 26.6 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS60415.1 - 5e-06 26.0 7.7 8.1e-06 25.3 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS60415.1 - 1.8e-05 24.3 7.0 2.8e-05 23.7 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS60415.1 - 3.3e-05 23.4 7.5 5.5e-05 22.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 ETS60415.1 - 0.00036 20.4 8.4 0.00056 19.8 5.8 1.3 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H_2 PF13832.1 ETS60415.1 - 0.061 13.3 2.5 0.13 12.2 1.7 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.1 ETS60415.1 - 0.37 10.4 7.8 0.69 9.5 5.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 ETS60415.1 - 0.38 10.9 5.4 1 9.5 3.8 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.2 ETS60415.1 - 2.4 8.2 10.9 4.1 7.5 7.5 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 ETS60415.1 - 4.2 7.3 4.3 11 5.9 3.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 ETS60415.1 - 8.7 6.1 8.7 14 5.4 6.0 1.4 1 0 0 1 1 1 0 PHD-finger DUF2665 PF11654.3 ETS60416.1 - 1.3e-19 69.4 0.1 1.9e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF2934 PF11154.3 ETS60416.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) RhoGEF PF00621.15 ETS60417.1 - 3.9e-38 131.1 0.1 7.3e-38 130.2 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 ETS60417.1 - 1.1e-18 66.3 1.1 7.1e-09 34.9 0.1 2.5 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 ETS60417.1 - 2.8e-16 59.1 0.0 7.9e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.1 ETS60417.1 - 1.1e-14 53.6 1.2 2.3e-08 33.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 ETS60417.1 - 2.8e-10 39.5 0.0 7e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 ETS60417.1 - 5.3e-09 35.3 1.3 1.1e-08 34.4 0.4 2.0 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.1 ETS60417.1 - 0.00026 21.0 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS60417.1 - 0.016 14.4 0.7 0.77 9.2 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 ETS60417.1 - 0.079 12.8 0.0 18 5.5 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain AA_permease PF00324.16 ETS60419.1 - 5.9e-125 417.3 44.0 6.6e-125 417.1 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS60419.1 - 1.5e-37 129.1 47.1 2e-37 128.7 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L23eN PF03939.8 ETS60420.1 - 5.5e-19 67.9 13.7 1.4e-18 66.6 9.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 ETS60420.1 - 9.6e-16 57.5 0.1 1.7e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 WD40 PF00400.27 ETS60421.1 - 0.035 13.9 0.4 8 6.5 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Pkinase PF00069.20 ETS60422.1 - 9e-25 87.2 0.0 1.4e-18 66.9 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60422.1 - 1.5e-06 27.4 0.0 5.7e-05 22.3 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase YABBY PF04690.8 ETS60423.1 - 1.3e-07 32.0 0.1 2.3e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 YABBY protein DUF1014 PF06244.7 ETS60423.1 - 0.00084 19.5 1.4 0.0012 19.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box_2 PF09011.5 ETS60423.1 - 0.0032 17.8 1.4 0.0064 16.8 1.0 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 ETS60423.1 - 0.0061 16.8 1.6 0.013 15.7 1.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Rotamase PF00639.16 ETS60424.1 - 2.3e-24 85.9 0.0 3.2e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 ETS60424.1 - 3.9e-20 72.2 0.0 4.7e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 ETS60424.1 - 1.9e-07 31.7 0.0 2.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 ETS60424.1 - 2.8e-06 27.0 0.3 2.8e-06 27.0 0.2 1.7 2 0 0 2 2 2 1 WW domain HIT PF01230.18 ETS60425.1 - 4.4e-25 88.0 0.2 6.8e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETS60425.1 - 8.3e-14 51.8 0.1 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 ETS60425.1 - 4.3e-05 23.1 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FHA PF00498.21 ETS60426.1 - 4.7e-08 33.0 0.0 8.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain CPSase_L_D2 PF02786.12 ETS60427.1 - 2.5e-53 180.4 0.0 5e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 ETS60427.1 - 7.7e-47 159.7 0.2 2.3e-46 158.2 0.2 1.8 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_chain PF00289.17 ETS60427.1 - 1.3e-32 112.1 0.1 2.7e-31 107.9 0.0 2.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS60427.1 - 2.8e-24 85.1 0.0 7.2e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 ETS60427.1 - 9.2e-11 41.8 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS60427.1 - 2.9e-10 39.3 0.0 3.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 ETS60427.1 - 3.8e-10 39.2 2.7 9.2e-10 38.0 1.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 ETS60427.1 - 0.0041 16.7 2.5 0.31 10.7 0.2 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 ETS60427.1 - 0.0048 16.7 0.0 0.019 14.8 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS60427.1 - 0.0067 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF1183 PF06682.7 ETS60428.1 - 1.2e-58 199.2 6.7 3.3e-58 197.7 4.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) PQ-loop PF04193.9 ETS60429.1 - 3.8e-28 96.8 11.9 3e-14 52.3 0.1 2.7 3 0 0 3 3 3 2 PQ loop repeat DUF1301 PF06979.7 ETS60429.1 - 0.0024 18.0 0.0 0.0084 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1301) PepSY_TM_2 PF13703.1 ETS60429.1 - 0.077 13.1 0.2 0.077 13.1 0.1 4.5 4 3 1 5 5 5 0 PepSY-associated TM helix ABM PF03992.11 ETS60430.1 - 1.4e-06 28.2 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aconitase PF00330.15 ETS60431.1 - 5.9e-184 611.9 0.1 7e-184 611.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS60431.1 - 3.9e-44 149.9 0.0 7.3e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Chitin_synth_1N PF08407.6 ETS60431.1 - 0.041 13.5 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Chitin synthase N-terminal BAF1_ABF1 PF04684.8 ETS60432.1 - 6.8 5.4 33.8 15 4.2 23.4 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 ETS60432.1 - 9.5 5.1 10.5 0.58 9.0 3.4 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter EF-hand_7 PF13499.1 ETS60433.1 - 8.6e-09 35.4 0.1 8.6e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETS60433.1 - 3.9e-08 32.5 0.1 0.0075 16.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETS60433.1 - 3.3e-07 29.1 0.1 0.0028 16.8 0.0 2.6 2 0 0 2 2 2 2 EF hand RRM_1 PF00076.17 ETS60433.1 - 6.2e-07 28.9 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_5 PF13202.1 ETS60433.1 - 2.2e-06 26.7 0.1 0.0016 17.6 0.0 2.6 2 0 0 2 2 2 2 EF hand RRM_6 PF14259.1 ETS60433.1 - 9.5e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EF-hand_8 PF13833.1 ETS60433.1 - 0.00015 21.3 0.2 0.0034 16.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair RRM_5 PF13893.1 ETS60433.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETS60435.1 - 2.6e-07 30.2 0.0 0.0035 17.1 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Peptidase_M16 PF00675.15 ETS60436.1 - 4e-56 188.9 0.2 8.9e-56 187.7 0.2 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 ETS60436.1 - 1.7e-42 145.1 0.0 2.4e-40 138.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain ENTH PF01417.15 ETS60437.1 - 1.8e-44 150.5 0.2 2.6e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 ETS60437.1 - 3.6e-05 22.6 0.0 5.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF3542 PF12061.3 ETS60437.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) GRP PF07172.6 ETS60437.1 - 0.22 12.0 14.1 0.47 10.9 9.8 1.5 1 0 0 1 1 1 0 Glycine rich protein family DNA_methylase PF00145.12 ETS60438.1 - 9.3e-49 166.3 0.0 1.7e-48 165.4 0.0 1.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 ETS60438.1 - 0.11 12.2 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 BAH domain Dioxygenase_C PF00775.16 ETS60439.1 - 2.7e-09 36.5 2.1 7.8e-07 28.5 0.0 2.6 2 1 0 2 2 2 2 Dioxygenase Abhydrolase_6 PF12697.2 ETS60440.1 - 4e-31 108.6 3.9 7.2e-31 107.8 2.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS60440.1 - 7.7e-14 51.7 0.1 1.5e-13 50.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS60440.1 - 3.7e-11 42.9 0.4 8e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 ETS60440.1 - 2.1e-09 37.1 0.3 5.7e-09 35.6 0.2 1.9 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Peptidase_S9 PF00326.16 ETS60440.1 - 3.2e-05 23.2 0.0 0.06 12.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 ETS60440.1 - 8.8e-05 22.0 0.1 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 ETS60440.1 - 0.0001 20.8 0.0 0.00038 19.0 0.0 1.9 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 ETS60440.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 ETS60440.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.13 ETS60440.1 - 0.073 12.3 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Arrestin_N PF00339.24 ETS60441.1 - 2.4e-05 24.1 0.0 0.00022 21.0 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ELFV_dehydrog PF00208.16 ETS60442.1 - 1.4e-50 172.2 0.0 2e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 ETS60442.1 - 4.5e-24 84.0 0.0 1.5e-16 59.1 0.0 2.5 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 ETS60442.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Herpes_gE PF02480.11 ETS60444.1 - 0.00047 18.5 0.1 0.00055 18.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 ETS60444.1 - 0.0054 16.9 0.3 0.0074 16.4 0.2 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF347 PF03988.7 ETS60444.1 - 0.014 15.2 0.9 0.028 14.3 0.6 1.5 1 1 0 1 1 1 0 Repeat of Unknown Function (DUF347) Peptidase_M56 PF05569.6 ETS60444.1 - 0.04 12.9 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4501 PF14946.1 ETS60444.1 - 0.079 12.4 2.6 1.2 8.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) PgaD PF13994.1 ETS60444.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein Ribosomal_L22 PF00237.14 ETS60445.1 - 2.7e-28 97.9 0.1 4.3e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PAP_central PF04928.12 ETS60446.1 - 1.4e-105 351.6 0.0 2.1e-105 351.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 ETS60446.1 - 6.5e-49 165.4 0.0 1.2e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 ETS60446.1 - 4.2e-09 36.6 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_5 PF12695.2 ETS60447.1 - 3.1e-05 23.7 0.2 0.00017 21.3 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS60447.1 - 0.0012 18.7 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS60447.1 - 0.0088 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 ETS60447.1 - 0.029 13.2 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 ETS60447.1 - 0.053 13.1 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) PIRT PF15099.1 ETS60447.1 - 0.085 12.0 0.1 12 5.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Proteasome PF00227.21 ETS60448.1 - 3.6e-56 189.4 0.4 4.8e-56 189.0 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS60448.1 - 2.1e-14 52.4 0.0 3.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MFS_1 PF07690.11 ETS60452.1 - 1.2e-29 103.1 32.1 1.2e-29 103.1 22.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1304 PF06993.7 ETS60452.1 - 0.21 11.3 7.4 0.33 10.6 0.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1304) Zn_clus PF00172.13 ETS60454.1 - 9.1e-07 28.6 8.3 1.7e-06 27.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS60454.1 - 5.5e-06 25.4 0.1 9.3e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1818 PF08848.6 ETS60454.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) BNR_2 PF13088.1 ETS60455.1 - 1.5e-07 31.0 0.8 1.3e-05 24.6 0.2 2.5 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 ETS60455.1 - 1.2e-05 24.4 7.7 0.027 14.2 0.3 4.5 3 0 0 3 3 3 2 BNR/Asp-box repeat Sugar_tr PF00083.19 ETS60457.1 - 2.2e-100 336.3 27.3 2.5e-100 336.1 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS60457.1 - 1.7e-22 79.6 44.4 1.5e-18 66.6 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 ETS60458.1 - 4.8e-30 104.6 0.0 6.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Dispanin PF04505.7 ETS60459.1 - 4.4 6.8 11.5 14 5.2 0.2 3.0 2 0 0 2 2 2 0 Interferon-induced transmembrane protein SIR2 PF02146.12 ETS60460.1 - 3.6e-26 91.9 0.1 7.9e-25 87.6 0.1 3.0 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 ETS60460.1 - 0.00025 20.7 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Cellulase PF00150.13 ETS60461.1 - 3.9e-11 42.6 7.0 1.4e-10 40.8 4.5 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Proteasome PF00227.21 ETS60462.1 - 1.7e-50 170.9 0.2 2.2e-50 170.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit mRNA_cap_enzyme PF01331.14 ETS60463.1 - 1.1e-43 149.1 0.0 1.4e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 ETS60463.1 - 1.6e-13 50.8 0.0 6.3e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 ETS60463.1 - 0.00014 21.2 0.0 0.0046 16.3 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain ThiF PF00899.16 ETS60464.1 - 7.8e-32 109.9 0.0 1.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 ETS60464.1 - 9.8e-05 22.4 0.0 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 ETS60464.1 - 0.097 11.8 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIS_C PF01096.13 ETS60465.1 - 4.3e-16 58.2 6.2 1e-15 57.0 0.3 3.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 ETS60465.1 - 1.1e-06 28.2 6.8 0.00041 19.9 0.3 3.2 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.2 ETS60465.1 - 0.00029 20.6 5.7 0.11 12.3 0.0 3.2 2 1 1 3 3 3 1 Double zinc ribbon TF_Zn_Ribbon PF08271.7 ETS60465.1 - 0.0017 17.6 8.0 0.21 10.9 0.5 2.6 2 1 0 2 2 2 2 TFIIB zinc-binding Lar_restr_allev PF14354.1 ETS60465.1 - 0.0029 17.8 8.9 0.016 15.5 0.5 3.2 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 ETS60465.1 - 0.0043 16.2 16.9 0.089 12.0 2.9 3.7 3 1 0 3 3 3 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ETS60465.1 - 0.0064 16.1 4.4 0.24 11.0 0.0 2.8 2 1 0 2 2 2 1 Putative transposase DNA-binding domain zf-C4_Topoisom PF01396.14 ETS60465.1 - 0.014 14.8 4.9 5.9 6.4 0.1 3.7 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Terminase_GpA PF05876.7 ETS60465.1 - 0.047 12.0 0.6 0.074 11.3 0.2 1.5 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-TFIIB PF13453.1 ETS60465.1 - 0.049 12.8 0.7 0.049 12.8 0.5 2.6 3 0 0 3 3 2 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.5 ETS60465.1 - 0.063 13.2 11.0 8.7 6.3 0.1 4.4 3 1 1 4 4 4 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 ETS60465.1 - 0.12 12.6 0.2 0.12 12.6 0.1 3.5 4 0 0 4 4 3 0 Zinc-finger double domain IBR PF01485.16 ETS60465.1 - 0.13 12.1 5.2 2.8 7.8 0.1 2.9 2 1 0 2 2 2 0 IBR domain DUF164 PF02591.10 ETS60465.1 - 0.24 11.2 4.1 2.3 8.0 0.0 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain zf-ISL3 PF14690.1 ETS60465.1 - 0.24 11.4 8.1 25 4.9 0.0 4.1 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prok-RING_1 PF14446.1 ETS60465.1 - 0.3 10.8 7.9 1.5 8.5 0.3 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 ETS60465.1 - 0.47 10.0 19.8 0.97 9.0 1.9 3.5 2 2 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 ETS60465.1 - 0.5 10.1 5.5 13 5.6 0.1 3.2 2 1 0 2 2 2 0 PhnA Zinc-Ribbon CpXC PF14353.1 ETS60465.1 - 1.4 8.9 5.3 50 3.8 1.3 3.6 3 1 0 3 3 3 0 CpXC protein zf-NADH-PPase PF09297.6 ETS60465.1 - 1.6 8.2 12.0 36 3.9 0.1 3.9 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.6 ETS60465.1 - 1.7 8.5 7.0 9.6 6.1 0.0 3.5 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_ribbon_recom PF13408.1 ETS60465.1 - 2.8 8.2 6.9 11 6.3 0.1 3.5 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain DUF2387 PF09526.5 ETS60465.1 - 4.2 7.3 7.4 5.9 6.8 0.2 2.9 3 1 0 3 3 2 0 Probable metal-binding protein (DUF2387) Ribosomal_S27e PF01667.12 ETS60465.1 - 5.5 6.6 9.0 7.1 6.2 0.0 3.9 3 1 1 4 4 4 0 Ribosomal protein S27 Zn_Tnp_IS1595 PF12760.2 ETS60465.1 - 6.3 6.6 11.0 12 5.8 1.6 3.5 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.1 ETS60465.1 - 8.1 6.2 9.5 4.1 7.1 0.0 3.8 4 0 0 4 4 4 0 Nudix N-terminal UPF0547 PF10571.4 ETS60465.1 - 8.3 6.2 18.1 1.1 9.0 0.2 4.0 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 AAA_5 PF07728.9 ETS60466.1 - 3e-115 380.1 0.1 1.5e-21 76.5 0.0 9.6 8 1 0 9 9 9 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETS60466.1 - 1.2e-22 79.9 0.0 6.5e-06 25.7 0.0 7.1 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS60466.1 - 8.8e-22 77.6 0.7 0.051 13.7 0.0 8.9 8 0 0 8 8 7 5 AAA domain AAA PF00004.24 ETS60466.1 - 1.9e-21 76.6 0.3 0.0041 17.3 0.0 7.0 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETS60466.1 - 1.2e-18 67.3 1.0 0.041 13.7 0.0 7.9 7 1 0 7 7 5 5 AAA domain AAA_17 PF13207.1 ETS60466.1 - 2.3e-17 63.9 0.0 0.42 11.4 0.0 6.9 5 0 0 5 5 5 5 AAA domain AAA_19 PF13245.1 ETS60466.1 - 8.4e-15 54.2 9.8 0.0017 18.0 0.2 7.1 6 0 0 6 6 6 3 Part of AAA domain Zeta_toxin PF06414.7 ETS60466.1 - 4.4e-14 52.0 2.8 0.032 13.3 0.0 7.3 7 0 0 7 7 6 4 Zeta toxin ABC_tran PF00005.22 ETS60466.1 - 4.9e-14 52.7 0.8 0.14 12.4 0.0 7.0 7 0 0 7 7 6 3 ABC transporter AAA_18 PF13238.1 ETS60466.1 - 6.6e-14 52.3 7.0 0.18 12.1 0.0 7.6 7 0 0 7 7 7 3 AAA domain T2SE PF00437.15 ETS60466.1 - 2.9e-13 49.3 1.1 0.14 11.0 0.0 6.5 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_28 PF13521.1 ETS60466.1 - 4.4e-13 49.5 2.4 0.05 13.5 0.0 6.6 6 0 0 6 6 5 3 AAA domain Sigma54_activ_2 PF14532.1 ETS60466.1 - 9.3e-13 48.4 1.3 0.0056 16.7 0.1 7.5 7 0 0 7 7 6 2 Sigma-54 interaction domain AAA_14 PF13173.1 ETS60466.1 - 9.5e-13 48.1 0.0 0.00086 19.2 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_29 PF13555.1 ETS60466.1 - 1.2e-12 47.1 2.3 0.086 12.3 0.0 6.2 6 0 0 6 6 6 3 P-loop containing region of AAA domain Sigma54_activat PF00158.21 ETS60466.1 - 1.1e-10 41.2 0.0 1.6 8.1 0.0 6.1 6 0 0 6 6 6 3 Sigma-54 interaction domain NACHT PF05729.7 ETS60466.1 - 1.1e-09 38.2 3.0 0.11 12.1 0.0 6.1 5 0 0 5 5 5 2 NACHT domain AAA_25 PF13481.1 ETS60466.1 - 1.2e-09 37.8 4.7 0.16 11.3 0.1 6.5 7 0 0 7 7 7 3 AAA domain Mg_chelatase PF01078.16 ETS60466.1 - 4.6e-09 35.7 3.7 0.19 10.8 0.1 6.7 8 0 0 8 8 7 2 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 ETS60466.1 - 6.4e-09 35.4 3.0 2.6 7.7 0.0 6.4 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 ETS60466.1 - 4.7e-08 33.1 0.3 2.2 8.4 0.0 6.3 6 0 0 6 6 6 1 RNA helicase MobB PF03205.9 ETS60466.1 - 2.3e-07 30.5 1.0 2.2 7.9 0.0 5.8 6 0 0 6 6 5 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETS60466.1 - 2.8e-07 31.0 0.4 8.3 6.9 0.0 6.3 6 0 0 6 6 6 0 Miro-like protein DUF258 PF03193.11 ETS60466.1 - 3e-06 26.5 1.2 3.3 6.8 0.0 5.4 6 0 0 6 6 5 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS60466.1 - 3e-06 27.3 7.5 0.0011 19.0 0.1 13.2 15 2 0 15 15 9 5 AAA ATPase domain cobW PF02492.14 ETS60466.1 - 6.2e-06 25.7 1.3 2.3 7.6 0.0 5.4 5 0 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 ETS60466.1 - 2e-05 23.6 0.7 0.1 11.4 0.0 4.7 6 0 0 6 6 6 1 Protein of unknown function (DUF815) Dynein_heavy PF03028.10 ETS60466.1 - 2.7e-05 22.4 0.0 0.0073 14.4 0.0 4.2 5 0 0 5 5 5 1 Dynein heavy chain and region D6 of dynein motor PduV-EutP PF10662.4 ETS60466.1 - 3.9e-05 23.1 0.5 4 6.9 0.1 5.3 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 ETS60466.1 - 0.00018 21.0 2.0 1.5 8.2 0.1 4.8 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 ETS60466.1 - 0.00018 21.4 0.0 1.9 8.5 0.0 4.8 5 0 0 5 5 4 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 ETS60466.1 - 0.00023 20.9 0.7 2.3 7.9 0.0 4.7 5 0 0 5 5 4 1 NTPase ResIII PF04851.10 ETS60466.1 - 0.00036 20.4 0.0 9.8 5.9 0.0 4.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 ETS60466.1 - 0.00068 18.4 0.2 9 4.8 0.0 4.1 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 ETS60466.1 - 0.0021 17.7 0.0 7.6 6.1 0.0 4.6 5 0 0 5 5 4 0 Archaeal ATPase ATP_bind_1 PF03029.12 ETS60466.1 - 0.0073 15.8 0.8 35 3.8 0.0 4.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 ETS60466.1 - 0.014 14.6 1.5 0.28 10.3 0.0 3.9 6 0 0 6 6 5 0 Chromatin associated protein KTI12 AAA_21 PF13304.1 ETS60466.1 - 0.017 15.0 0.0 2.5 7.9 0.0 3.9 5 0 0 5 5 4 0 AAA domain PhoH PF02562.11 ETS60466.1 - 0.072 12.3 1.1 30 3.7 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein TIP49 PF06068.8 ETS60466.1 - 0.13 11.0 1.8 3.4 6.2 0.1 3.5 4 0 0 4 4 3 0 TIP49 C-terminus Dynamin_N PF00350.18 ETS60466.1 - 0.79 9.5 5.3 19 5.0 0.0 5.2 6 0 0 6 6 5 0 Dynamin family AAA_6 PF12774.2 ETS60466.1 - 0.8 9.1 0.0 40 3.6 0.0 3.6 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_7 PF12775.2 ETS60466.1 - 1.1 8.2 0.0 28 3.6 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region D3 AAA_PrkA PF08298.6 ETS60466.1 - 2 7.0 0.5 1.1e+02 1.3 0.0 3.0 3 0 0 3 3 3 0 PrkA AAA domain NOB1_Zn_bind PF08772.6 ETS60466.1 - 6 6.7 0.0 14 5.6 0.0 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like PPV_E1_C PF00519.12 ETS60466.1 - 6.6 5.2 0.0 18 3.8 0.0 1.6 2 0 0 2 2 1 0 Papillomavirus helicase Arginosuc_synth PF00764.14 ETS60468.1 - 1.1e-158 528.3 0.0 1.5e-158 527.8 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PGK PF00162.14 ETS60468.1 - 6.5e-147 489.0 0.8 8.4e-147 488.7 0.5 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase QueC PF06508.8 ETS60468.1 - 0.0005 19.4 0.0 0.0013 18.1 0.0 1.7 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 ETS60468.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 ETS60468.1 - 0.074 11.5 0.0 0.15 10.5 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase RNA_pol_Rpc4 PF05132.9 ETS60469.1 - 2.4e-28 98.6 0.5 2.4e-28 98.6 0.3 3.8 3 1 0 3 3 3 2 RNA polymerase III RPC4 W2 PF02020.13 ETS60470.1 - 7.5e-17 61.0 1.4 7.5e-17 61.0 0.9 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 ETS60470.1 - 1e-11 43.7 5.4 4.7e-06 25.8 0.5 4.2 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 ETS60470.1 - 5.8e-09 35.6 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 ETS60470.1 - 0.00032 20.7 0.0 0.0006 19.9 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 ETS60470.1 - 0.046 13.2 8.8 0.021 14.3 1.2 3.4 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Clp1 PF06807.9 ETS60471.1 - 5e-08 32.9 0.0 5.1e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 ETS60471.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 ETS60471.1 - 0.012 15.6 0.1 0.012 15.6 0.1 3.1 2 1 1 3 3 3 0 AAA ATPase domain MTBP_N PF14918.1 ETS60471.1 - 0.2 11.0 1.8 0.37 10.1 1.3 1.3 1 0 0 1 1 1 0 MDM2-binding CLN3 PF02487.12 ETS60472.1 - 2e-62 211.2 15.4 8.1e-35 120.3 0.1 4.8 2 1 2 4 4 4 4 CLN3 protein Snf7 PF03357.16 ETS60473.1 - 6.3e-42 142.8 19.4 3.5e-41 140.4 13.3 1.9 2 0 0 2 2 2 1 Snf7 DUF1043 PF06295.7 ETS60473.1 - 0.075 12.6 3.0 0.13 11.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) V_ATPase_I PF01496.14 ETS60473.1 - 0.16 9.7 3.7 0.19 9.5 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.7 ETS60473.1 - 0.19 11.6 4.7 0.64 9.9 3.3 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.7 ETS60473.1 - 0.33 10.6 11.0 0.64 9.7 7.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ist1 PF03398.9 ETS60473.1 - 0.38 10.1 6.6 0.52 9.7 4.6 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Prefoldin PF02996.12 ETS60473.1 - 0.5 10.0 5.2 0.28 10.8 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit COG2 PF06148.6 ETS60473.1 - 0.6 9.9 8.3 0.22 11.4 2.9 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 KxDL PF10241.4 ETS60473.1 - 0.71 9.8 7.6 3.4 7.6 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein PspA_IM30 PF04012.7 ETS60473.1 - 0.99 8.7 21.3 0.019 14.3 4.4 2.1 1 1 0 2 2 2 0 PspA/IM30 family YlqD PF11068.3 ETS60473.1 - 3.6 7.6 15.4 12 5.9 9.5 2.1 1 1 1 2 2 2 0 YlqD protein DivIC PF04977.10 ETS60473.1 - 9.5 5.7 13.2 1.7 8.1 2.2 2.9 3 0 0 3 3 3 0 Septum formation initiator DUF4618 PF15397.1 ETS60473.1 - 9.8 5.4 15.7 3.3 6.9 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Pkinase PF00069.20 ETS60474.1 - 1.1e-61 208.2 0.0 1.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60474.1 - 2.2e-35 121.9 0.0 3.4e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60474.1 - 3.5e-09 36.0 0.0 6.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS60474.1 - 0.034 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETS60474.1 - 0.036 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 ETS60474.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HLH PF00010.21 ETS60475.1 - 0.00029 20.4 0.1 0.00064 19.3 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 ETS60475.1 - 0.0042 17.5 4.6 0.013 15.9 3.2 1.8 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 Neur_chan_memb PF02932.11 ETS60475.1 - 2.3 8.0 5.0 5 6.9 0.5 2.7 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region D123 PF07065.9 ETS60476.1 - 3.2e-77 259.5 0.0 3.9e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 ETS60476.1 - 0.019 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) RRM_6 PF14259.1 ETS60477.1 - 4.1e-11 42.6 0.0 6.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS60477.1 - 5.8e-11 41.8 0.1 1.8e-10 40.3 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60477.1 - 1.9e-06 27.6 0.0 4.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltrn_RNA_3 PF02598.12 ETS60478.1 - 3.7e-79 266.0 0.0 4.6e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Pol_alpha_B_N PF08418.5 ETS60478.1 - 5.1 6.5 6.0 8.9 5.7 4.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Cid2 PF09774.4 ETS60479.1 - 0.06 13.4 1.7 0.084 12.9 1.2 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF4557 PF15101.1 ETS60479.1 - 9.3 6.0 7.7 26 4.5 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) Corona_nucleoca PF00937.13 ETS60480.1 - 0.16 10.8 3.1 0.3 9.9 2.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Kei1 PF08552.6 ETS60481.1 - 1.2e-51 175.1 2.7 1.2e-51 175.1 1.9 1.6 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 ETS60481.1 - 0.14 12.1 8.5 0.25 11.2 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Herpes_gE PF02480.11 ETS60481.1 - 0.17 10.1 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E KOW PF00467.24 ETS60482.1 - 4.5e-07 29.3 0.6 1.2e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 KOW motif WD40 PF00400.27 ETS60483.1 - 2.5e-64 211.0 8.8 7.1e-09 35.2 0.0 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 ETS60483.1 - 1.8e-10 40.3 0.1 4.1e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 ETS60483.1 - 5.9e-10 37.9 9.1 0.017 13.2 0.0 6.3 3 1 2 6 6 6 6 Nucleoporin Nup120/160 F-box PF00646.28 ETS60483.1 - 8.8e-10 37.9 0.1 2.2e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Chromo PF00385.19 ETS60484.1 - 3.7e-13 48.9 0.2 1.2e-12 47.3 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 ETS60484.1 - 3e-09 36.5 0.1 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Prog_receptor PF02161.10 ETS60484.1 - 0.68 8.6 11.5 1.1 8.0 8.0 1.3 1 0 0 1 1 1 0 Progesterone receptor DUF2305 PF10230.4 ETS60485.1 - 1.3e-45 155.9 0.0 1.1e-44 152.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 ETS60485.1 - 8.4e-12 45.4 4.7 8.4e-12 45.4 3.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS60485.1 - 8.5e-08 32.0 0.3 2.1e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS60485.1 - 0.0053 16.3 0.1 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.16 ETS60485.1 - 0.0077 15.4 0.1 0.016 14.4 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.8 ETS60485.1 - 0.0089 15.6 0.0 0.034 13.7 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.8 ETS60485.1 - 0.022 14.3 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 Serine hydrolase Pkinase PF00069.20 ETS60486.1 - 4.4e-52 176.8 0.0 5.7e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60486.1 - 2.4e-41 141.5 0.0 3.7e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60486.1 - 0.0009 18.2 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS60486.1 - 0.015 15.0 4.4 0.32 10.6 3.1 2.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 ETS60487.1 - 3.9e-28 97.6 2.1 2.6e-19 69.3 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS60487.1 - 4.3e-17 60.9 4.4 5.9e-08 32.1 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETS60487.1 - 6.9e-16 58.2 0.6 1.1e-06 28.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS60487.1 - 7.4e-15 53.5 1.1 7.2e-05 22.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 ETS60487.1 - 1.5e-11 44.0 5.9 2.1e-06 27.7 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) AhpC-TSA PF00578.16 ETS60488.1 - 7.6e-25 87.0 0.0 1e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS60488.1 - 3.6e-14 52.5 0.1 5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 ETS60488.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme M60-like PF13402.1 ETS60488.1 - 0.02 13.7 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase M60-like family HMG14_17 PF01101.13 ETS60488.1 - 0.087 13.5 10.1 0.17 12.5 7.0 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 SAC3_GANP PF03399.11 ETS60489.1 - 0.0005 19.6 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PTPA PF03095.10 ETS60490.1 - 4.7e-94 314.9 0.0 7.7e-94 314.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SPX PF03105.14 ETS60491.1 - 0.067 12.9 0.1 0.078 12.7 0.1 1.1 1 0 0 1 1 1 0 SPX domain DUF724 PF05266.9 ETS60491.1 - 0.14 11.7 1.7 0.2 11.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) tRNA-synt_2b PF00587.20 ETS60492.1 - 1.4e-43 148.4 0.0 2.5e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS60492.1 - 4e-20 71.5 0.1 8.4e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 ETS60492.1 - 1.2e-13 50.7 0.0 1.3e-11 44.1 0.0 2.5 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 ETS60492.1 - 3.6e-10 39.5 0.0 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Ndc1_Nup PF09531.5 ETS60492.1 - 0.041 12.3 1.1 0.057 11.8 0.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4230 PF14014.1 ETS60493.1 - 0.19 11.5 0.8 0.33 10.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) Hex_IIIa PF02455.11 ETS60493.1 - 0.35 9.5 8.2 0.024 13.3 1.7 1.8 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) CDC45 PF02724.9 ETS60493.1 - 3.1 5.7 7.3 3.8 5.4 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Aminotran_5 PF00266.14 ETS60494.1 - 1.7e-09 36.8 0.0 4.6e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V AIG2 PF06094.7 ETS60495.1 - 1.8e-14 54.0 0.0 5.3e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 AIG2-like family Acyltransferase PF01553.16 ETS60495.1 - 1.7e-12 46.9 0.0 3.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Monellin PF09200.5 ETS60495.1 - 0.19 11.3 0.0 0.58 9.8 0.0 1.8 1 0 0 1 1 1 0 Monellin Formyl_trans_N PF00551.14 ETS60496.1 - 4.3e-19 68.7 0.0 6.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 ETS60496.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain zf-DHHC PF01529.15 ETS60497.1 - 4.9e-30 104.2 0.0 8.1e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2124 PF09897.4 ETS60497.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Oxidored_q3 PF00499.15 ETS60497.1 - 0.41 10.4 2.3 2 8.1 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Aminotran_1_2 PF00155.16 ETS60498.1 - 2.8e-56 191.0 0.0 3.7e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS60498.1 - 0.00012 21.3 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 ETS60498.1 - 0.0088 14.6 0.0 0.051 12.1 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.15 ETS60498.1 - 0.011 14.0 0.0 0.02 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 ETS60498.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III MFS_1 PF07690.11 ETS60499.1 - 4.4e-09 35.5 26.5 8.6e-09 34.5 18.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS60499.1 - 5.9e-05 22.6 4.3 5.9e-05 22.6 3.0 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 TRAM_LAG1_CLN8 PF03798.11 ETS60499.1 - 0.015 14.8 0.7 0.015 14.8 0.5 2.3 2 0 0 2 2 2 0 TLC domain Sugar_tr PF00083.19 ETS60499.1 - 0.032 12.8 14.3 0.011 14.3 6.1 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter Cation_ATPase_C PF00689.16 ETS60499.1 - 0.1 12.1 12.7 0.38 10.2 0.4 3.6 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus DUF3816 PF12822.2 ETS60499.1 - 6.1 6.7 15.1 0.83 9.5 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) PC-Esterase PF13839.1 ETS60500.1 - 0.0028 17.5 0.0 0.0077 16.0 0.0 1.7 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ribosomal_L6 PF00347.18 ETS60501.1 - 3.1e-22 78.8 0.2 1.8e-09 37.9 0.1 3.1 2 1 0 3 3 3 3 Ribosomal protein L6 NUDIX PF00293.23 ETS60502.1 - 1.4e-26 92.7 0.0 2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain SAC3_GANP PF03399.11 ETS60503.1 - 8.6e-35 120.1 0.1 1.1e-34 119.7 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 ETS60503.1 - 8.3e-29 100.1 0.0 2.7e-28 98.5 0.0 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 NAM PF02365.10 ETS60503.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 No apical meristem (NAM) protein DUF3680 PF12441.3 ETS60503.1 - 0.33 10.8 0.1 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3680) RRM_1 PF00076.17 ETS60504.1 - 2.9e-12 46.0 0.6 2.4e-08 33.4 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Yae1_N PF09811.4 ETS60504.1 - 2.2e-07 30.2 8.5 5.6e-07 28.9 5.9 1.8 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_5 PF13893.1 ETS60504.1 - 7.7e-06 25.6 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60504.1 - 1.5e-05 24.8 0.5 0.00074 19.4 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Acyl-CoA_dh_1 PF00441.19 ETS60505.1 - 2.7e-44 150.9 2.5 4.7e-44 150.0 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS60505.1 - 2.3e-36 124.7 0.0 4.9e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETS60505.1 - 7.7e-21 73.3 0.1 1.8e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS60505.1 - 2.9e-20 72.8 0.3 5.2e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 ETS60505.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Mgm101p PF06420.7 ETS60507.1 - 7.2e-84 279.3 0.0 9.6e-84 278.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Leo1 PF04004.8 ETS60508.1 - 3e-53 180.0 0.1 9.5e-53 178.3 0.1 2.0 1 0 0 1 1 1 1 Leo1-like protein SPT6_acidic PF14632.1 ETS60508.1 - 0.013 15.6 16.1 0.013 15.6 11.2 6.7 6 1 0 6 6 6 0 Acidic N-terminal SPT6 Ribosomal_L37e PF01907.14 ETS60509.1 - 4e-25 87.3 12.1 4e-25 87.3 8.4 1.7 2 1 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 ETS60509.1 - 0.0011 18.7 1.7 0.0016 18.2 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 ETS60509.1 - 0.023 14.3 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 SelR domain HypA PF01155.14 ETS60509.1 - 0.1 12.2 1.0 0.14 11.8 0.7 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF1462 PF07315.6 ETS60509.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zf-ribbon_3 PF13248.1 ETS60509.1 - 0.43 9.8 3.5 1.6 8.0 2.6 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 ETS60509.1 - 1.9 8.2 5.1 3 7.5 3.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 ETS60509.1 - 9.2 5.7 10.8 0.67 9.3 0.3 2.6 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e Ribosomal_L7Ae PF01248.21 ETS60510.1 - 1.9e-23 81.7 0.0 2.2e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.23 ETS60510.1 - 0.025 14.5 0.0 0.054 13.5 0.0 1.5 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase GTP_cyclohydro2 PF00925.15 ETS60513.1 - 2.7e-65 218.7 0.1 1e-59 200.5 0.0 2.4 2 0 0 2 2 2 2 GTP cyclohydrolase II Arm PF00514.18 ETS60514.1 - 2.1e-96 312.8 5.3 7e-13 47.8 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS60514.1 - 3.1e-29 101.0 1.0 3.8e-08 33.4 0.0 6.2 1 1 5 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 ETS60514.1 - 7.4e-22 77.2 0.7 3.3e-08 33.7 0.0 6.0 5 2 1 6 6 5 3 HEAT-like repeat IBB PF01749.15 ETS60514.1 - 3.8e-20 71.8 8.3 6.7e-20 71.0 5.8 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 ETS60514.1 - 2e-18 64.7 1.0 3.2e-05 23.6 0.0 7.0 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 ETS60514.1 - 3.6e-07 28.8 0.0 5.7e-05 21.6 0.0 2.8 1 1 1 2 2 2 1 Adaptin N terminal region Arm_2 PF04826.8 ETS60514.1 - 1.2e-05 24.6 0.0 0.042 12.9 0.0 3.5 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.9 ETS60514.1 - 0.00018 20.7 0.0 2.7 7.0 0.0 3.2 1 1 2 3 3 3 3 V-ATPase subunit H RICTOR_V PF14668.1 ETS60514.1 - 0.00034 20.4 1.7 0.31 11.0 0.0 4.1 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 ETS60514.1 - 0.0005 19.9 0.0 0.27 11.1 0.0 4.1 3 2 1 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 ETS60514.1 - 0.003 17.8 1.0 1.4 9.6 0.1 4.3 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 ETS60514.1 - 0.015 13.5 0.0 1.7 6.8 0.0 2.7 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF330 PF03886.8 ETS60514.1 - 0.018 14.4 0.1 0.1 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF330) Mo25 PF08569.6 ETS60514.1 - 0.053 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Mo25-like Nefa_Nip30_N PF10187.4 ETS60515.1 - 3.9e-20 71.9 6.3 3.9e-20 71.9 4.4 1.6 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 bZIP_2 PF07716.10 ETS60516.1 - 0.0036 17.1 6.4 0.0067 16.2 4.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper WAC_Acf1_DNA_bd PF10537.4 ETS60517.1 - 6.1e-38 129.0 0.1 2.1e-37 127.3 0.0 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 ETS60517.1 - 2.7e-12 46.2 0.1 4.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 ETS60517.1 - 5.2e-05 23.0 0.1 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 ETS60517.1 - 8.6e-05 22.2 0.0 0.00031 20.4 0.0 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 ETS60517.1 - 0.00094 19.0 0.1 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PP2C PF00481.16 ETS60518.1 - 1.5e-36 126.0 0.0 5.9e-33 114.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Ubiq_cyt_C_chap PF03981.7 ETS60519.1 - 1e-27 96.7 0.1 1.3e-25 89.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone P3A PF08727.6 ETS60521.1 - 0.00025 20.3 0.3 0.11 11.8 0.0 3.4 3 0 0 3 3 3 1 Poliovirus 3A protein like PhoD PF09423.5 ETS60521.1 - 0.0003 19.4 0.2 0.00054 18.6 0.1 1.4 2 0 0 2 2 2 1 PhoD-like phosphatase ATP12 PF07542.6 ETS60521.1 - 0.032 14.1 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 ATP12 chaperone protein Med15_fungi PF05397.7 ETS60522.1 - 1.2e-32 112.3 1.7 1.2e-32 112.3 1.2 4.6 6 0 0 6 6 6 1 Mediator complex subunit 15 ARID PF01388.16 ETS60522.1 - 3.3e-18 65.3 0.0 1.3e-17 63.4 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ABC2_membrane PF01061.19 ETS60523.1 - 1e-34 119.5 18.1 1e-34 119.5 12.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 ETS60523.1 - 2.4e-23 82.9 0.0 4.2e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS60523.1 - 2.2e-05 24.6 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS60523.1 - 0.0062 16.5 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 ETS60523.1 - 0.0073 15.3 26.8 0.017 14.1 18.6 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 ETS60523.1 - 0.0084 15.3 0.1 0.023 13.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETS60523.1 - 0.04 13.3 0.8 0.15 11.4 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS60523.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 ETS60523.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_33 PF13671.1 ETS60523.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS60523.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS60523.1 - 0.17 12.6 0.0 0.33 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETS60523.1 - 0.21 12.1 0.0 0.46 10.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 ETS60523.1 - 0.22 11.2 0.1 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ebp2 PF05890.7 ETS60525.1 - 2.8e-89 299.0 16.5 2.8e-89 299.0 11.4 2.2 2 1 1 3 3 3 1 Eukaryotic rRNA processing protein EBP2 Pkinase PF00069.20 ETS60526.1 - 1.6e-49 168.4 0.0 2.5e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60526.1 - 7.2e-47 159.6 0.0 1.1e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 ETS60526.1 - 4.5e-06 26.2 4.9 9.2e-06 25.2 3.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 ETS60526.1 - 0.0082 15.8 0.1 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS60526.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 ETS60526.1 - 0.13 11.9 4.0 0.26 11.0 2.8 1.5 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 ETS60526.1 - 0.21 11.6 3.1 0.43 10.6 2.2 1.6 1 0 0 1 1 1 0 C1-like domain C1_2 PF03107.11 ETS60526.1 - 0.57 10.3 7.1 1 9.5 4.9 1.4 1 0 0 1 1 1 0 C1 domain Kelch_4 PF13418.1 ETS60527.1 - 4.5e-20 71.1 13.8 7.9e-06 25.5 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 ETS60527.1 - 9.5e-09 35.1 21.8 0.0057 16.7 0.3 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS60527.1 - 8.5e-08 31.9 9.0 0.0054 16.6 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 ETS60527.1 - 0.00046 19.8 1.9 1.5 8.6 0.0 3.7 4 0 0 4 4 4 2 Kelch motif HET PF06985.6 ETS60527.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 ETS60528.1 - 5.2e-24 84.5 0.0 1.1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS60528.1 - 2.5e-06 27.2 6.0 4.3e-06 26.5 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2380 PF09533.5 ETS60528.1 - 0.16 11.3 1.9 0.38 10.1 1.3 1.6 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) AMP-binding PF00501.23 ETS60529.1 - 1e-84 284.3 0.0 1.4e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS60529.1 - 4.1e-08 34.0 0.1 1.2e-07 32.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 ETS60529.1 - 0.38 10.8 0.0 0.79 9.8 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain COX5B PF01215.14 ETS60530.1 - 2e-36 124.6 0.0 2.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 ETS60530.1 - 0.079 12.8 1.5 0.13 12.0 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain CHZ PF09649.5 ETS60531.1 - 8.4 5.7 7.6 1.4 8.2 1.7 2.4 2 1 0 2 2 2 0 Histone chaperone domain CHZ GST_N PF02798.15 ETS60532.1 - 8.1e-16 57.9 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS60532.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS60532.1 - 2.8e-08 33.5 0.2 4.5e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS60532.1 - 4e-08 33.1 0.0 7.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS60532.1 - 2.6e-07 30.5 0.0 5.2e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS60532.1 - 9.6e-05 22.7 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MAPEG PF01124.13 ETS60533.1 - 1.5e-13 50.4 2.1 2.4e-13 49.7 1.5 1.4 1 0 0 1 1 1 1 MAPEG family Mago-bind PF09282.5 ETS60534.1 - 8.7e-13 47.5 2.2 8.7e-13 47.5 1.5 2.4 2 0 0 2 2 2 1 Mago binding DUF2742 PF10888.3 ETS60534.1 - 1.6 8.6 6.4 0.14 12.1 0.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2742) F-box-like PF12937.2 ETS60535.1 - 0.0037 16.9 1.1 0.0076 15.9 0.8 1.6 1 0 0 1 1 1 1 F-box-like Ribul_P_3_epim PF00834.14 ETS60536.1 - 6e-64 214.8 0.1 8.7e-64 214.3 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 ETS60536.1 - 0.03 13.8 0.0 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PG_binding_3 PF09374.5 ETS60536.1 - 0.033 14.1 0.0 0.094 12.7 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain C2 PF00168.25 ETS60537.1 - 3e-18 65.4 0.0 6.9e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain Nup84_Nup100 PF04121.8 ETS60538.1 - 5.3e-106 354.9 0.0 6.4e-55 186.1 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 TFIIB PF00382.14 ETS60539.1 - 1.5e-37 127.2 0.7 2.7e-22 78.3 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ETS60539.1 - 6.1e-13 47.8 1.4 9.7e-13 47.2 1.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 ETS60539.1 - 0.00059 19.7 0.0 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain PG_binding_1 PF01471.13 ETS60539.1 - 0.058 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Cyclin_N PF00134.18 ETS60539.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Svf1 PF08622.5 ETS60540.1 - 8.2e-99 330.6 0.0 1e-98 330.3 0.0 1.1 1 0 0 1 1 1 1 Svf1-like PQQ PF01011.16 ETS60540.1 - 0.052 13.0 0.2 0.53 9.9 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Aconitase PF00330.15 ETS60541.1 - 3e-72 243.6 0.5 1.6e-67 228.0 0.4 3.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS60541.1 - 1.5e-19 70.3 0.0 5.1e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Aconitase C-terminal domain Cyclin_N PF00134.18 ETS60542.1 - 2.2e-36 124.1 0.3 3.9e-36 123.4 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETS60542.1 - 1.1e-05 25.2 0.1 1.1e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain SR-25 PF10500.4 ETS60542.1 - 0.0031 17.0 19.5 0.0031 17.0 13.5 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF1490 PF07371.7 ETS60545.1 - 0.093 12.6 0.8 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) GatB_N PF02934.10 ETS60546.1 - 8.4e-106 353.0 0.0 1.4e-105 352.3 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 ETS60546.1 - 6.5e-26 90.8 0.0 1.4e-25 89.7 0.0 1.5 1 1 0 1 1 1 1 GatB domain Beta_elim_lyase PF01212.16 ETS60547.1 - 2.3e-67 227.1 0.0 3.2e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pcc1 PF09341.5 ETS60547.1 - 6.5e-17 61.3 0.2 1.5e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Pcc1 DegT_DnrJ_EryC1 PF01041.12 ETS60547.1 - 0.00054 19.1 0.0 0.00082 18.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 ETS60547.1 - 0.0008 18.4 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 ETS60547.1 - 0.07 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PC_rep PF01851.17 ETS60548.1 - 2.5e-43 143.9 15.5 1.7e-08 34.2 0.0 9.7 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 ETS60548.1 - 3e-17 62.6 3.2 1.1e-10 41.5 0.0 4.8 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 ETS60548.1 - 3.9e-09 36.7 0.5 0.0023 18.3 0.0 4.8 3 0 0 3 3 3 3 HEAT-like repeat HEAT PF02985.17 ETS60548.1 - 1.8e-07 30.6 0.4 2.3 8.4 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 ETS60548.1 - 0.039 14.4 1.5 1e+02 3.8 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Hus1 PF04005.7 ETS60549.1 - 3.9e-86 288.6 0.5 4.5e-86 288.4 0.3 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_N PF00705.13 ETS60549.1 - 0.00092 18.7 0.4 0.0023 17.4 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 ETS60549.1 - 0.0029 16.7 0.2 0.018 14.2 0.2 2.1 1 1 0 1 1 1 1 Rad9 VPS28 PF03997.7 ETS60550.1 - 7.5e-58 195.2 3.4 8.7e-58 195.0 2.4 1.0 1 0 0 1 1 1 1 VPS28 protein Bestrophin PF01062.16 ETS60550.1 - 0.18 10.7 1.6 0.2 10.5 0.5 1.5 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel tRNA-synt_1c PF00749.16 ETS60551.1 - 2.4e-107 358.2 0.0 3.8e-107 357.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 ETS60551.1 - 1.3e-34 119.3 0.2 2.5e-34 118.4 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 ETS60551.1 - 2.1e-07 31.3 0.6 8.8e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS60551.1 - 0.001 19.0 1.0 0.01 15.7 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS60551.1 - 0.012 15.5 0.1 0.031 14.1 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RNase_H2-Ydr279 PF09468.5 ETS60551.1 - 2.3 7.3 6.3 4.5 6.3 4.3 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LSM PF01423.17 ETS60552.1 - 3.8e-17 61.5 0.4 5.4e-17 61.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain DUF3296 PF11726.3 ETS60552.1 - 0.037 13.6 0.0 0.04 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Rad60-SLD PF11976.3 ETS60554.1 - 1.7e-07 30.8 0.0 4.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.15 ETS60554.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 UBX domain Response_reg PF00072.19 ETS60557.1 - 2.1e-18 66.3 0.0 7.7e-10 38.7 0.0 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HATPase_c PF02518.21 ETS60557.1 - 8.8e-18 64.0 0.2 1.8e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS60557.1 - 1.2e-16 60.4 0.3 3.4e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 ETS60557.1 - 1.2e-06 28.7 0.0 0.00057 20.0 0.0 3.7 3 0 0 3 3 3 1 GAF domain RRM_1 PF00076.17 ETS60558.1 - 8.4e-18 63.7 0.0 1.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60558.1 - 1.3e-12 47.4 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 ETS60558.1 - 1e-07 32.1 10.7 5e-06 26.7 4.2 3.4 3 1 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 ETS60558.1 - 9.1e-07 28.6 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb1_7 PF04990.7 ETS60558.1 - 0.12 12.0 0.1 1.1 8.9 0.0 1.9 1 1 0 2 2 2 0 RNA polymerase Rpb1, domain 7 Proteasome PF00227.21 ETS60559.1 - 1.3e-50 171.3 0.1 1.7e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS60559.1 - 1.9e-12 46.2 0.2 3.1e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Na_H_Exchanger PF00999.16 ETS60562.1 - 8.1e-66 222.0 47.6 1.1e-65 221.6 33.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4407 PF14362.1 ETS60562.1 - 0.025 13.5 0.1 0.025 13.5 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) TUDOR PF00567.19 ETS60563.1 - 7.3e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 ETS60563.1 - 3.7e-06 26.2 0.0 3.7e-06 26.2 0.0 3.5 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) DUF3391 PF11871.3 ETS60563.1 - 0.056 13.6 0.3 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PWWP PF00855.12 ETS60563.1 - 0.07 13.3 0.2 0.5 10.5 0.1 2.2 1 1 0 1 1 1 0 PWWP domain Abhydrolase_6 PF12697.2 ETS60564.1 - 1.5e-19 70.8 0.0 1.9e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS60564.1 - 8e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS60564.1 - 1.1e-07 31.6 0.2 6.2e-07 29.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS60564.1 - 0.03 14.1 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase Peptidase_S9 PF00326.16 ETS60564.1 - 0.051 12.7 0.1 0.39 9.8 0.0 2.5 3 1 0 3 3 3 0 Prolyl oligopeptidase family FSH1 PF03959.8 ETS60564.1 - 0.086 12.2 0.3 1.1 8.7 0.2 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 ETS60564.1 - 0.11 11.9 0.1 3 7.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase CH PF00307.26 ETS60565.1 - 1.2e-68 227.9 0.0 3.1e-19 69.0 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 ETS60565.1 - 2.4e-09 36.7 0.0 0.31 10.7 0.0 4.4 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 ETS60565.1 - 1.4e-06 28.3 0.5 6.4e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS60565.1 - 0.00016 20.6 0.2 0.037 13.3 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 ETS60565.1 - 0.0025 17.5 0.3 11 6.2 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 ETS60565.1 - 0.096 12.3 0.1 0.34 10.5 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair Prefoldin_2 PF01920.15 ETS60566.1 - 1.4e-19 69.8 3.9 1.8e-19 69.4 2.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 ETS60566.1 - 0.00055 19.5 2.2 0.0007 19.2 1.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF812 PF05667.6 ETS60566.1 - 0.013 14.0 2.4 0.016 13.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.3 ETS60566.1 - 0.041 13.5 3.7 0.074 12.7 2.5 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding NTR2 PF15458.1 ETS60566.1 - 0.17 11.0 3.2 0.28 10.3 2.2 1.6 1 1 0 1 1 1 0 Nineteen complex-related protein 2 HrpB7 PF09486.5 ETS60566.1 - 0.2 11.5 4.8 2.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 ETS60566.1 - 1.3 8.5 9.4 3.2 7.3 6.5 1.6 1 1 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 ETS60566.1 - 1.7 8.7 6.4 1.4 9.0 0.7 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil NDUFB10 PF10249.4 ETS60567.1 - 0.0031 17.6 0.2 0.0035 17.4 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF4456 PF14644.1 ETS60567.1 - 0.06 12.5 0.2 0.066 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) CheZ PF04344.8 ETS60567.1 - 0.084 12.5 0.3 0.088 12.4 0.2 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Methyltransf_4 PF02390.12 ETS60568.1 - 1.2e-49 168.0 0.0 3.6e-37 127.3 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 ETS60568.1 - 0.00065 20.2 0.1 0.0031 18.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS60568.1 - 0.0037 17.2 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS60568.1 - 0.025 13.9 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 ETS60568.1 - 0.033 14.6 0.0 0.11 13.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 ETS60568.1 - 0.041 14.2 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60568.1 - 0.05 14.0 0.0 6.4 7.3 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 ETS60568.1 - 0.078 12.5 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF3292 PF11696.3 ETS60569.1 - 0.0023 15.8 0.0 0.0023 15.8 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) NAP PF00956.13 ETS60570.1 - 1.7e-41 141.9 0.5 1.7e-41 141.9 0.4 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) YL1 PF05764.8 ETS60570.1 - 0.018 14.6 5.1 0.023 14.2 3.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoplasmin PF03066.10 ETS60570.1 - 0.036 13.6 6.9 0.11 11.9 4.4 1.9 2 0 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 ETS60570.1 - 3.5 5.4 9.3 3.8 5.3 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 ETS60571.1 - 3.3e-38 128.2 6.8 1.5e-09 37.3 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 ETS60571.1 - 2.9e-32 110.3 1.2 6.4e-32 109.2 0.9 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 ETS60571.1 - 0.00032 20.1 0.0 0.026 14.0 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 ETS60571.1 - 0.089 11.5 0.0 0.19 10.4 0.0 1.5 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.3 ETS60571.1 - 0.13 10.3 1.6 0.68 7.9 0.0 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 SPX PF03105.14 ETS60572.1 - 3.6e-55 187.6 0.4 6e-55 186.9 0.3 1.4 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 ETS60572.1 - 1.2e-29 103.4 37.4 1.6e-29 103.0 25.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 ETS60572.1 - 4.9e-19 68.1 36.1 4.1e-13 48.6 13.7 2.1 1 1 1 2 2 2 2 Citrate transporter Pro_isomerase PF00160.16 ETS60573.1 - 9e-42 142.9 0.0 1.9e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 ETS60573.1 - 8.5e-05 21.8 0.1 0.00037 19.7 0.0 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger zf-ZPR1 PF03367.8 ETS60574.1 - 3.8e-105 348.0 1.2 2e-52 176.5 0.0 3.1 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 ETS60574.1 - 0.0018 17.9 3.2 0.32 10.7 0.3 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 ETS60574.1 - 0.047 12.9 5.1 1.3 8.2 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain Cytochrome_C554 PF13435.1 ETS60574.1 - 0.11 12.5 1.4 11 6.0 0.4 2.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime UPF0547 PF10571.4 ETS60574.1 - 0.17 11.5 2.4 2 8.1 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DZR PF12773.2 ETS60574.1 - 0.19 11.5 7.0 0.79 9.5 0.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 ETS60574.1 - 0.26 11.2 7.6 9.8 6.2 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 ETS60574.1 - 0.53 9.8 7.6 0.76 9.3 0.3 3.2 2 1 1 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ETS60574.1 - 0.66 9.6 4.8 7.6 6.2 0.2 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 ETS60574.1 - 2.3 8.5 7.0 31 4.9 0.1 3.8 3 1 0 3 3 3 0 Restriction alleviation protein Lar Response_reg PF00072.19 ETS60576.1 - 1.8e-20 73.0 0.0 6.1e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 ETS60576.1 - 1.9e-18 66.2 0.3 3.7e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS60576.1 - 1.7e-07 31.1 0.5 5e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 ETS60576.1 - 6e-05 23.1 0.0 0.00032 20.7 0.0 2.3 2 0 0 2 2 2 1 GAF domain HTH_3 PF01381.17 ETS60577.1 - 6.6e-15 54.7 0.3 1.1e-14 53.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 ETS60577.1 - 1.7e-10 40.7 0.1 4.2e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_19 PF12844.2 ETS60577.1 - 1.5e-07 31.3 0.1 2.2e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 ETS60577.1 - 2.3e-06 27.7 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 ETS60577.1 - 0.048 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain GTP1_OBG PF01018.17 ETS60577.1 - 0.1 12.2 2.3 0.36 10.4 0.7 2.0 1 1 1 2 2 2 0 GTP1/OBG F-box-like PF12937.2 ETS60578.1 - 5.6e-09 35.5 0.3 5.6e-09 35.5 0.2 2.5 3 0 0 3 3 3 1 F-box-like WD40 PF00400.27 ETS60578.1 - 6e-06 25.9 5.5 2.4e-05 24.0 0.5 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat F-box PF00646.28 ETS60578.1 - 9e-05 22.0 0.5 0.00024 20.6 0.3 1.8 1 0 0 1 1 1 1 F-box domain DEAD PF00270.24 ETS60579.1 - 6.7e-40 136.3 0.0 2.8e-39 134.3 0.0 2.0 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS60579.1 - 4.7e-26 90.4 0.1 1.8e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETS60579.1 - 6.1e-07 28.5 0.0 1.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS60579.1 - 1.4e-05 24.9 0.3 0.00048 19.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETS60579.1 - 0.0052 16.5 0.1 0.023 14.4 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain Herpes_ori_bp PF02399.10 ETS60579.1 - 0.043 11.7 0.0 0.073 11.0 0.0 1.3 1 0 0 1 1 1 0 Origin of replication binding protein DUF1253 PF06862.7 ETS60579.1 - 0.093 11.1 0.0 0.33 9.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) MIF4G PF02854.14 ETS60580.1 - 1.6e-22 79.9 0.0 3.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 ETS60580.1 - 5.7e-13 48.5 0.0 2.1e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 MA3 domain WD40 PF00400.27 ETS60581.1 - 3.9e-45 150.1 17.3 1.7e-10 40.3 0.0 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat DUF4592 PF15262.1 ETS60581.1 - 0.18 12.3 7.5 0.44 11.1 5.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) RRS1 PF04939.7 ETS60582.1 - 2.7e-57 192.8 1.9 2.7e-57 192.8 1.3 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) DUF2407_C PF13373.1 ETS60582.1 - 3.1 7.7 4.9 2.3 8.1 2.3 1.6 1 1 1 2 2 2 0 DUF2407 C-terminal domain NAD_binding_8 PF13450.1 ETS60584.1 - 6e-10 39.0 0.0 1.8e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS60584.1 - 1.3e-05 24.2 0.5 0.0089 14.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS60584.1 - 0.00011 21.9 0.1 0.3 10.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS60584.1 - 0.00019 21.5 0.0 0.084 12.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS60584.1 - 0.19 10.1 0.0 12 4.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FMN_dh PF01070.13 ETS60585.1 - 2.5e-122 408.1 0.4 3e-122 407.9 0.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS60585.1 - 2e-22 78.7 0.0 7.4e-22 76.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS60585.1 - 1.7e-05 23.8 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS60585.1 - 0.00018 20.5 0.2 0.00031 19.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 ETS60585.1 - 0.0028 16.7 0.0 0.85 8.6 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 ETS60585.1 - 0.035 13.3 0.4 0.41 9.8 0.1 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein Arm PF00514.18 ETS60585.1 - 0.059 13.2 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat KaiC PF06745.8 ETS60585.1 - 0.11 11.5 0.0 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 KaiC Band_7 PF01145.20 ETS60586.1 - 3.5e-27 95.4 1.6 5.4e-27 94.8 1.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family LRS4 PF10422.4 ETS60586.1 - 0.068 12.5 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 IlvN PF07991.7 ETS60587.1 - 3.9e-43 146.6 0.0 6e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 ETS60587.1 - 2.1e-42 144.4 0.0 3.5e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 ETS60587.1 - 0.0021 18.4 0.2 0.0071 16.7 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 ETS60587.1 - 0.042 13.6 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_31 PF13847.1 ETS60588.1 - 6.4e-21 74.5 0.0 9.5e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60588.1 - 4.7e-20 71.8 0.0 1.6e-18 66.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS60588.1 - 5.1e-18 65.3 0.0 8.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS60588.1 - 5.4e-16 58.7 0.0 1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS60588.1 - 2e-14 53.8 0.0 3.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS60588.1 - 5.4e-11 42.0 0.0 7.6e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 ETS60588.1 - 2.4e-10 41.0 0.3 1.6e-09 38.3 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS60588.1 - 1.2e-09 38.2 0.0 3.9e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETS60588.1 - 0.00024 20.5 0.0 0.00084 18.7 0.0 1.8 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 ETS60588.1 - 0.00052 19.4 0.0 0.044 13.1 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 ETS60588.1 - 0.0046 16.5 0.1 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 ETS60588.1 - 0.078 12.0 0.1 0.55 9.3 0.1 2.3 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 ETS60588.1 - 0.081 12.6 0.0 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain GST_N_3 PF13417.1 ETS60589.1 - 4.5e-10 39.6 0.0 8.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS60589.1 - 6.2e-08 32.4 0.0 2.5e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS60589.1 - 2.1e-07 30.8 0.0 4.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS60589.1 - 2.6e-07 30.5 0.0 1.6e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS60589.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS60589.1 - 0.016 15.6 0.1 0.052 14.0 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M24 PF00557.19 ETS60590.1 - 2.1e-47 161.3 0.0 2.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 ETS60590.1 - 2.5e-35 120.7 0.0 5.2e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Telomere_Sde2_2 PF13297.1 ETS60590.1 - 0.13 11.5 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Telomere stability C-terminal Snf7 PF03357.16 ETS60592.1 - 1.9e-34 118.4 9.2 2.4e-34 118.1 6.3 1.0 1 0 0 1 1 1 1 Snf7 Gluconate_2-dh3 PF13618.1 ETS60592.1 - 0.14 12.2 3.3 0.29 11.2 2.3 1.8 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 PPR_2 PF13041.1 ETS60593.1 - 2.5e-43 145.8 0.1 1.3e-08 34.6 0.0 7.3 6 2 1 7 7 7 6 PPR repeat family PPR_1 PF12854.2 ETS60593.1 - 3.1e-29 100.1 3.8 0.0022 17.4 0.0 10.0 10 0 0 10 10 10 7 PPR repeat PPR_3 PF13812.1 ETS60593.1 - 5e-26 88.7 24.6 0.003 17.7 0.0 14.1 17 0 0 17 17 17 8 Pentatricopeptide repeat domain PPR PF01535.15 ETS60593.1 - 4.8e-18 63.8 13.3 0.00034 20.3 0.1 11.5 12 0 0 12 12 12 3 PPR repeat MNE1 PF13762.1 ETS60593.1 - 0.19 11.7 0.0 21 5.1 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial splicing apparatus component RIO1 PF01163.17 ETS60594.1 - 0.00011 21.6 0.3 0.00019 20.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family CobT PF06213.7 ETS60594.1 - 0.0059 15.7 14.5 0.0072 15.4 10.1 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETS60594.1 - 0.15 9.9 16.4 0.18 9.7 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETS60594.1 - 0.15 10.0 14.9 0.19 9.7 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 ETS60594.1 - 0.19 10.6 6.4 0.29 10.0 4.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleo_P87 PF07267.6 ETS60594.1 - 0.23 10.1 7.3 0.31 9.6 5.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.7 ETS60594.1 - 0.36 10.0 8.6 0.51 9.5 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 ETS60594.1 - 1.7 8.1 12.6 3 7.3 8.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin DNA_pol_phi PF04931.8 ETS60594.1 - 1.7 6.2 13.6 1.9 6.1 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2890 PF11081.3 ETS60594.1 - 2 8.4 14.3 0.16 12.0 6.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PPP4R2 PF09184.6 ETS60594.1 - 3.8 6.9 12.6 5.3 6.4 8.7 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4098 PF13345.1 ETS60595.1 - 3.5e-11 42.8 1.9 2e-06 27.6 0.1 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF4098) OppC_N PF12911.2 ETS60595.1 - 0.031 13.6 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DDE_1 PF03184.14 ETS60596.1 - 1.4e-33 115.9 0.0 2e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 ETS60596.1 - 1.4e-09 37.6 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SAICAR_synt PF01259.13 ETS60597.1 - 3.5e-80 268.7 0.0 4.5e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Kinesin PF00225.18 ETS60598.1 - 2.4e-108 361.8 0.6 5.9e-108 360.5 0.4 1.7 1 0 0 1 1 1 1 Kinesin motor domain DHquinase_II PF01220.14 ETS60598.1 - 0.029 13.7 1.5 0.13 11.5 0.6 2.4 2 0 0 2 2 2 0 Dehydroquinase class II DUF1295 PF06966.7 ETS60599.1 - 2.2e-37 128.6 3.5 3.7e-36 124.6 2.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) WD40 PF00400.27 ETS60600.1 - 2.3e-57 188.9 19.5 5.8e-14 51.3 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 ETS60600.1 - 5.3e-10 39.3 0.7 1.3e-06 28.2 0.1 3.4 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETS60600.1 - 3.1e-08 32.2 13.7 0.0018 16.5 0.1 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETS60600.1 - 0.00011 21.1 0.1 0.27 9.9 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region DUF3312 PF11768.3 ETS60600.1 - 0.00036 18.8 0.6 0.0076 14.5 0.0 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 ETS60600.1 - 0.00045 19.7 1.3 0.0066 15.9 0.9 2.2 1 1 0 1 1 1 1 PQQ-like domain Hira PF07569.6 ETS60600.1 - 0.044 12.9 3.7 0.29 10.3 0.1 3.3 3 1 2 5 5 5 0 TUP1-like enhancer of split RNA_pol_Rpb4 PF03874.11 ETS60601.1 - 5.9e-13 48.8 0.6 2e-12 47.1 0.4 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 Rhomboid PF01694.17 ETS60602.1 - 4.6e-10 39.6 14.1 1.5e-09 38.0 9.8 1.8 1 1 0 1 1 1 1 Rhomboid family GHMP_kinases_N PF00288.21 ETS60602.1 - 0.076 13.0 1.5 0.3 11.1 1.0 2.1 1 0 0 1 1 1 0 GHMP kinases N terminal domain CcmD PF04995.9 ETS60602.1 - 0.9 9.3 7.0 1.6 8.5 0.0 3.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Fasciclin PF02469.17 ETS60604.1 - 2.8e-33 114.6 3.1 6e-23 81.2 0.3 2.3 2 0 0 2 2 2 2 Fasciclin domain GST_N_3 PF13417.1 ETS60605.1 - 3.1e-16 59.3 0.0 6.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS60605.1 - 5.1e-11 42.4 0.0 9.7e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS60605.1 - 2.8e-07 30.5 0.0 5.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 ETS60605.1 - 0.00056 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 ETS60605.1 - 0.0012 18.6 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2944 PF11161.3 ETS60605.1 - 0.048 13.3 0.0 0.14 11.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) Cupin_1 PF00190.17 ETS60606.1 - 5.3e-25 87.5 0.1 6.8e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 ETS60606.1 - 6.1e-24 83.3 0.6 2.3e-13 49.4 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 ETS60606.1 - 1.5e-12 47.3 0.0 3.7e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 ETS60606.1 - 4.5e-06 25.9 0.0 0.0057 16.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 ETS60606.1 - 7.4e-05 22.4 0.0 0.059 12.9 0.0 2.3 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_6 PF12852.2 ETS60606.1 - 0.00013 21.6 0.1 0.081 12.5 0.0 2.4 2 0 0 2 2 2 2 Cupin ARD PF03079.9 ETS60606.1 - 0.0047 16.8 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 ARD/ARD' family 3-HAO PF06052.7 ETS60606.1 - 0.058 12.8 0.0 8.6 5.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 ETS60606.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Ectoine_synth PF06339.7 ETS60606.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Ectoine synthase adh_short PF00106.20 ETS60607.1 - 5.7e-25 88.1 5.8 1e-24 87.3 4.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS60607.1 - 1e-12 48.0 3.9 1.5e-12 47.5 2.7 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS60607.1 - 1.1e-10 41.6 0.3 1.4e-10 41.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP28 PF10252.4 ETS60607.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 V-ATPase_C PF03223.10 ETS60608.1 - 2.2e-122 408.5 0.4 2.5e-122 408.4 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Imm29 PF15575.1 ETS60608.1 - 0.28 10.7 2.8 6.4 6.3 1.1 2.5 2 1 0 2 2 2 0 Immunity protein 29 DUF4404 PF14357.1 ETS60608.1 - 0.34 11.3 3.9 6.2 7.3 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PTS_2-RNA PF01885.11 ETS60609.1 - 1.7e-54 183.9 0.1 4.3e-54 182.6 0.0 1.6 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ctr PF04145.10 ETS60609.1 - 0.28 11.2 1.0 0.52 10.3 0.7 1.4 1 0 0 1 1 1 0 Ctr copper transporter family tRNA_int_end_N2 PF12928.2 ETS60610.1 - 3.1e-18 64.9 0.0 5.9e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 ETS60610.1 - 0.013 15.0 0.4 0.04 13.4 0.0 1.9 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain CMAS PF02353.15 ETS60611.1 - 2.5e-35 121.8 3.7 5.1e-35 120.8 2.6 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 ETS60611.1 - 3.1e-13 49.5 0.0 1.2e-12 47.6 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS60611.1 - 1.6e-12 47.4 0.1 3.9e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60611.1 - 1e-11 45.1 0.0 2.9e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS60611.1 - 1.4e-10 41.7 0.0 7e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 ETS60611.1 - 3e-08 33.2 0.0 5.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 ETS60611.1 - 5.7e-08 33.1 0.0 1.5e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS60611.1 - 5.6e-06 26.6 0.0 2.1e-05 24.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain TehB PF03848.9 ETS60611.1 - 0.00018 20.7 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 ETS60611.1 - 0.0018 17.3 0.0 0.0035 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 ETS60611.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETS60611.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 ETS60611.1 - 0.031 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2422 PF10337.4 ETS60612.1 - 1e-78 265.2 16.9 1.8e-77 261.1 1.0 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 ETS60612.1 - 7.3e-59 199.1 0.0 1.5e-58 198.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 ETS60612.1 - 1.3e-09 38.0 13.2 1.3e-09 38.0 9.1 3.6 2 2 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 ETS60612.1 - 0.027 13.1 4.3 0.065 11.8 3.0 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter UBX PF00789.15 ETS60613.1 - 4.2e-08 33.1 0.0 7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain Pec_lyase_C PF00544.14 ETS60614.1 - 2.2e-20 72.9 0.1 3.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 ETS60614.1 - 2.1e-05 24.2 0.9 4.5e-05 23.2 0.6 1.5 1 0 0 1 1 1 1 Right handed beta helix region CAF-1_p150 PF11600.3 ETS60614.1 - 0.0085 15.4 26.4 0.014 14.7 18.3 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 ETS60614.1 - 0.66 9.8 20.6 1 9.1 14.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asparaginase_2 PF01112.13 ETS60615.1 - 6.3e-46 156.5 0.9 4.5e-38 130.7 0.0 2.2 2 0 0 2 2 2 2 Asparaginase DUF619 PF04768.8 ETS60618.1 - 7.4e-34 116.6 0.2 7.9e-22 77.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) PMM PF03332.8 ETS60619.1 - 5.7e-99 330.1 0.6 1.1e-98 329.1 0.4 1.5 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Mre11_DNA_bind PF04152.9 ETS60619.1 - 1e-45 155.7 0.5 4.7e-45 153.5 0.0 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 ETS60619.1 - 2e-23 82.8 0.2 3.3e-23 82.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS60619.1 - 1.6e-06 28.0 0.0 8.6e-06 25.6 0.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Hydrolase_3 PF08282.7 ETS60619.1 - 0.00088 18.9 0.0 0.0072 15.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MSP1_C PF07462.6 ETS60619.1 - 0.27 9.5 3.2 0.52 8.6 2.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Siah-Interact_N PF09032.6 ETS60619.1 - 0.91 9.6 6.7 0.07 13.1 0.7 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal Cyto_heme_lyase PF01265.12 ETS60620.1 - 7.1e-72 242.1 5.5 1.9e-71 240.6 3.8 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Rcd1 PF04078.8 ETS60621.1 - 5e-128 425.4 1.9 6.2e-128 425.1 1.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like NIT PF08376.5 ETS60621.1 - 0.0037 16.8 0.2 0.0061 16.1 0.2 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing CRA PF06589.6 ETS60621.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Peptidase_M76 PF09768.4 ETS60622.1 - 1.2e-66 223.4 0.2 1.6e-66 223.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 ETS60622.1 - 0.025 14.2 1.4 0.038 13.6 0.5 1.6 1 1 0 1 1 1 0 SprT-like family Abhydrolase_5 PF12695.2 ETS60623.1 - 4.8e-22 78.2 0.0 1.1e-21 77.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS60623.1 - 9.7e-18 64.8 0.9 3.8e-16 59.6 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS60623.1 - 1.5e-10 41.0 0.0 3.2e-06 26.8 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 ETS60623.1 - 4.7e-05 22.0 0.1 0.0029 16.1 0.0 2.4 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 ETS60623.1 - 9.4e-05 21.7 0.0 0.002 17.4 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 ETS60623.1 - 0.0015 18.0 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 ETS60623.1 - 0.002 17.3 0.0 0.024 13.8 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 ETS60623.1 - 0.0045 16.7 0.0 0.18 11.4 0.0 2.5 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 ETS60623.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 ETS60623.1 - 0.071 12.5 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.7 ETS60623.1 - 0.089 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Esterase PF00756.15 ETS60623.1 - 0.14 11.6 0.1 0.23 10.8 0.1 1.4 1 1 0 1 1 1 0 Putative esterase ADH_zinc_N PF00107.21 ETS60624.1 - 1.2e-23 83.0 0.6 1.9e-23 82.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS60624.1 - 4.6e-21 74.6 2.5 2.7e-20 72.1 0.7 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AA_permease_2 PF13520.1 ETS60626.1 - 5.2e-48 163.6 54.2 6.9e-48 163.2 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS60626.1 - 5e-27 94.3 51.4 6.7e-27 93.9 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Toxin_47 PF15527.1 ETS60627.1 - 0.048 13.4 2.5 0.057 13.1 1.8 1.1 1 0 0 1 1 1 0 Putative toxin 47 OapA_N PF08525.6 ETS60627.1 - 0.41 10.4 0.0 0.41 10.4 0.0 2.2 3 0 0 3 3 3 0 Opacity-associated protein A N-terminal motif MARVEL PF01284.18 ETS60627.1 - 0.71 9.6 5.5 1.4 8.7 3.8 1.7 1 1 0 1 1 1 0 Membrane-associating domain DUF4345 PF14248.1 ETS60627.1 - 3 7.3 7.4 0.96 8.9 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Fungal_trans PF04082.13 ETS60628.1 - 6.7e-26 90.7 0.0 1.2e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4140 PF13600.1 ETS60628.1 - 0.042 14.3 0.1 0.38 11.2 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PrpF PF04303.8 ETS60629.1 - 5e-86 288.7 0.1 9.4e-86 287.8 0.0 1.3 1 1 0 1 1 1 1 PrpF protein Mito_carr PF00153.22 ETS60630.1 - 1.1e-62 207.7 12.0 1.2e-22 79.4 0.3 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 ETS60631.1 - 3.6e-76 256.5 13.9 5.1e-76 256.0 9.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS60631.1 - 1e-20 73.7 25.3 2.4e-13 49.5 5.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CopD PF05425.8 ETS60633.1 - 0.037 14.2 0.0 0.037 14.2 0.0 2.9 2 1 0 2 2 2 0 Copper resistance protein D ECH PF00378.15 ETS60634.1 - 6e-40 136.8 0.1 7.5e-36 123.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family ADH_zinc_N PF00107.21 ETS60635.1 - 2.5e-18 65.8 0.0 4.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS60635.1 - 2.4e-13 51.0 0.0 1.4e-11 45.3 0.0 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS60635.1 - 3.3e-08 33.2 0.0 3.6e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cupin_8 PF13621.1 ETS60636.1 - 0.0042 16.6 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 ETS60636.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain DDE_3 PF13358.1 ETS60637.1 - 2.3e-20 72.8 0.0 3.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 ETS60637.1 - 4e-11 42.8 6.6 4e-11 42.8 4.5 2.4 2 1 1 3 3 3 1 Transposase U5_2-snRNA_bdg PF10597.4 ETS60637.1 - 0.044 13.3 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 rve PF00665.21 ETS60637.1 - 0.056 13.5 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain p450 PF00067.17 ETS60641.1 - 5.8e-41 140.4 0.0 9.1e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 ETS60642.1 - 7.4e-50 170.0 0.1 9.7e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_zinc_N PF00107.21 ETS60643.1 - 1.4e-13 50.5 0.0 2.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS60643.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS60643.1 - 0.011 16.6 0.0 0.026 15.4 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_C48 PF02902.14 ETS60644.1 - 5.1e-21 75.2 0.0 7.4e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Phage_integrase PF00589.17 ETS60645.1 - 0.004 16.8 0.4 0.0082 15.8 0.3 1.5 1 0 0 1 1 1 1 Phage integrase family DUF4246 PF14033.1 ETS60646.1 - 1.4e-182 607.8 0.0 1.7e-182 607.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 ETS60646.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 ETS60646.1 - 0.053 14.0 0.3 1.3 9.5 0.1 3.0 3 1 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily Peptidase_M48 PF01435.13 ETS60648.1 - 3.3e-39 134.7 0.1 7.8e-39 133.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 ETS60648.1 - 0.014 14.3 0.0 0.014 14.3 0.0 2.9 4 0 0 4 4 4 0 BlaR1 peptidase M56 Peptidase_MA_2 PF13485.1 ETS60648.1 - 0.082 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily SprT-like PF10263.4 ETS60648.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Fungal_trans PF04082.13 ETS60649.1 - 2.6e-40 137.9 0.1 4.4e-40 137.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS60649.1 - 4.9e-08 32.8 10.6 0.0015 18.7 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS60649.1 - 0.001 19.2 13.4 0.057 13.7 1.3 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETS60649.1 - 0.12 12.3 0.4 0.34 10.8 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS60649.1 - 0.28 11.5 5.3 0.21 11.9 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain NOA36 PF06524.7 ETS60649.1 - 2.3 7.4 10.3 3.9 6.6 7.1 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.6 ETS60649.1 - 8.1 5.0 4.2 12 4.4 2.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SpoIIE PF07228.7 ETS60650.1 - 1.5e-06 28.0 0.4 0.12 12.0 0.1 3.4 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 ETS60650.1 - 0.00025 20.5 0.0 0.016 14.5 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C Cu-oxidase_3 PF07732.10 ETS60651.1 - 1.4e-39 134.5 4.4 2.2e-38 130.6 0.7 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS60651.1 - 1.5e-33 115.9 0.1 2.6e-32 111.9 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS60651.1 - 1.6e-33 115.1 9.1 2e-30 105.0 0.4 4.2 3 1 0 3 3 3 2 Multicopper oxidase Phosphoesterase PF04185.9 ETS60653.1 - 1.1e-22 80.8 4.2 1.8e-22 80.0 2.9 1.3 1 0 0 1 1 1 1 Phosphoesterase family Fer4_12 PF13353.1 ETS60654.1 - 0.00025 21.1 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 ETS60654.1 - 0.00074 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 ETS60654.1 - 0.029 14.5 0.0 0.095 12.8 0.0 1.9 1 1 0 1 1 1 0 Radical SAM superfamily Fer2 PF00111.22 ETS60655.1 - 9.6e-08 31.6 0.9 9.6e-08 31.6 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain zf-C2H2 PF00096.21 ETS60656.1 - 2.1e-05 24.5 13.5 0.002 18.3 2.4 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS60656.1 - 0.0013 18.8 3.2 0.0013 18.8 2.2 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS60656.1 - 0.0018 18.4 16.9 0.0099 16.1 1.7 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger GTP_EFTU PF00009.22 ETS60657.1 - 4.9e-56 189.1 0.1 8.9e-56 188.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ETS60657.1 - 1.7e-34 117.9 0.1 5.4e-34 116.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 ETS60657.1 - 8.7e-31 105.5 0.0 2.3e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 ETS60657.1 - 5.8e-22 77.3 0.1 1.6e-21 75.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS60657.1 - 5.5e-13 48.8 0.0 1.5e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 adh_short_C2 PF13561.1 ETS60657.1 - 0.013 15.2 0.4 0.029 14.1 0.3 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ribosomal_60s PF00428.14 ETS60657.1 - 3.7 7.9 16.0 7.4 7.0 4.0 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein SKN1 PF03935.10 ETS60658.1 - 3.9e-181 602.6 1.7 4.8e-181 602.2 1.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 ETS60660.1 - 4.9e-189 628.6 5.1 5.7e-189 628.4 3.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Rot1 PF10681.4 ETS60661.1 - 1.1e-60 204.5 0.2 1.4e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal SKN1 PF03935.10 ETS60663.1 - 3.3e-183 609.4 0.2 3.8e-183 609.2 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Pyr_redox_3 PF13738.1 ETS60664.1 - 3e-18 66.6 0.0 1.5e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS60664.1 - 1.8e-13 49.5 0.0 5.5e-12 44.6 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS60664.1 - 1.1e-10 41.0 0.0 1.3e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS60664.1 - 1.2e-06 28.5 0.0 0.045 13.6 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS60664.1 - 0.0011 18.9 0.1 0.012 15.6 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS60664.1 - 0.0017 18.1 0.2 9 6.0 0.0 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS60664.1 - 0.1 13.0 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 ETS60665.1 - 4.7e-79 265.7 0.0 6e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS60665.1 - 1.2e-11 45.3 0.0 3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TAFII28 PF04719.9 ETS60666.1 - 2.3e-21 75.3 0.2 1e-16 60.4 0.1 2.3 1 1 1 2 2 2 2 hTAFII28-like protein conserved region Saccharop_dh PF03435.13 ETS60667.1 - 4e-112 375.0 0.0 6.6e-112 374.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 ETS60667.1 - 2.9e-89 298.2 0.0 4.6e-89 297.5 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 ETS60667.1 - 0.0025 18.0 0.1 0.014 15.7 0.0 2.3 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS60667.1 - 0.0074 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS60667.1 - 0.024 14.6 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_12 PF08242.7 ETS60667.1 - 0.055 13.9 0.1 0.47 10.9 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Shikimate_DH PF01488.15 ETS60667.1 - 0.083 12.9 1.0 0.63 10.1 0.1 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF2325 PF10087.4 ETS60667.1 - 0.23 11.2 1.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF4383 PF14325.1 ETS60668.1 - 0.07 13.1 0.4 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) ECM1 PF05782.6 ETS60669.1 - 0.015 14.0 0.6 0.015 14.0 0.4 2.1 1 1 2 3 3 3 0 Extracellular matrix protein 1 (ECM1) Zn_clus PF00172.13 ETS60670.1 - 5.6e-05 22.9 14.3 8.3e-05 22.4 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-K PF11802.3 ETS60671.1 - 9.9e-07 28.2 8.5 0.00013 21.2 5.8 2.4 1 1 0 1 1 1 1 Centromere-associated protein K FeoC PF09012.5 ETS60671.1 - 0.015 14.9 0.1 0.054 13.2 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator Imm3 PF14425.1 ETS60671.1 - 0.65 9.9 3.6 4.7 7.2 0.1 3.3 4 0 0 4 4 4 0 Immunity protein Imm3 ResIII PF04851.10 ETS60672.1 - 1.1e-19 70.9 0.0 2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS60672.1 - 3.1e-14 52.5 0.0 7.8e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS60672.1 - 1.3e-13 50.8 0.0 2.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS60672.1 - 0.00042 20.4 0.3 0.0047 17.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 ETS60672.1 - 0.00054 18.9 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SNF2_N PF00176.18 ETS60672.1 - 0.00055 18.8 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain cobW PF02492.14 ETS60672.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 ETS60672.1 - 0.012 14.6 0.1 0.045 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 ETS60672.1 - 0.014 14.9 0.7 1.2 8.6 0.0 3.1 2 1 1 3 3 3 0 AAA domain RIC3 PF15361.1 ETS60673.1 - 0.64 10.2 2.0 1.3 9.2 1.4 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Pkinase PF00069.20 ETS60675.1 - 3e-75 252.7 0.0 4e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60675.1 - 1.6e-36 125.6 0.0 2.5e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60675.1 - 1.7e-08 33.8 0.0 2.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 ETS60675.1 - 0.0039 16.5 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family zf-C4H2 PF10146.4 ETS60675.1 - 0.01 15.9 2.0 0.062 13.3 1.4 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein UBA_2 PF08587.6 ETS60675.1 - 0.012 15.7 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YukC PF10140.4 ETS60675.1 - 0.26 9.8 0.0 0.42 9.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Corona_nucleoca PF00937.13 ETS60675.1 - 3 6.6 8.4 8.9 5.1 2.3 2.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Tubulin PF00091.20 ETS60676.1 - 2.2e-70 236.8 0.0 3.3e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS60676.1 - 1.1e-47 161.2 0.2 1.8e-47 160.5 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETS60676.1 - 1.2e-07 31.8 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETS60676.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Mago_nashi PF02792.9 ETS60677.1 - 4.7e-75 250.0 0.2 5.2e-75 249.9 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3368 PF11848.3 ETS60677.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Surp PF01805.15 ETS60678.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Surp module Cpn60_TCP1 PF00118.19 ETS60679.1 - 2.1e-119 399.3 5.6 2.5e-119 399.0 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn10 PF00166.16 ETS60680.1 - 1.3e-25 89.1 0.0 1.5e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Actin PF00022.14 ETS60681.1 - 9.4e-42 142.8 0.0 1.3e-38 132.4 0.0 3.1 2 1 0 2 2 2 2 Actin ThiF PF00899.16 ETS60682.1 - 5.3e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 ETS60682.1 - 0.019 14.5 0.2 0.19 11.3 0.0 2.4 3 0 0 3 3 3 0 MoeZ/MoeB domain SMC_N PF02463.14 ETS60683.1 - 4.4e-67 225.5 0.0 1.1e-66 224.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETS60683.1 - 6.9e-22 77.6 0.4 6.9e-22 77.6 0.3 2.5 3 0 0 3 3 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETS60683.1 - 5.7e-13 49.4 8.0 4.6e-06 26.8 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 ETS60683.1 - 3.7e-06 27.4 38.3 3.7e-06 27.4 26.6 5.6 2 2 0 2 2 1 1 AAA domain AAA_29 PF13555.1 ETS60683.1 - 8.7e-05 21.9 0.1 0.00048 19.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Spc7 PF08317.6 ETS60683.1 - 0.00026 19.7 15.7 0.00026 19.7 10.9 6.8 3 2 4 7 7 7 3 Spc7 kinetochore protein AAA_15 PF13175.1 ETS60683.1 - 0.00041 19.5 8.2 0.00041 19.5 5.7 1.7 2 0 0 2 2 2 1 AAA ATPase domain Filament PF00038.16 ETS60683.1 - 0.00062 19.3 73.6 0.046 13.1 1.1 7.4 2 2 3 5 5 5 4 Intermediate filament protein IncA PF04156.9 ETS60683.1 - 0.0012 18.4 8.6 0.0012 18.4 6.0 6.9 4 2 3 7 7 7 3 IncA protein Reo_sigmaC PF04582.7 ETS60683.1 - 0.002 17.3 0.5 0.002 17.3 0.4 5.2 3 2 4 7 7 7 2 Reovirus sigma C capsid protein DUF4200 PF13863.1 ETS60683.1 - 0.0055 16.6 6.0 0.0055 16.6 4.1 8.4 6 3 2 9 9 7 1 Domain of unknown function (DUF4200) ABC_tran PF00005.22 ETS60683.1 - 0.033 14.4 0.0 0.033 14.4 0.0 6.3 5 1 0 6 6 6 0 ABC transporter AAA_13 PF13166.1 ETS60683.1 - 0.16 10.4 71.8 0.56 8.5 11.8 5.7 3 2 2 5 5 5 0 AAA domain Pirin PF02678.11 ETS60684.1 - 3.3e-30 104.1 1.5 1.1e-29 102.4 0.5 1.9 2 0 0 2 2 2 1 Pirin Cupin_2 PF07883.6 ETS60684.1 - 5.2e-09 35.4 0.7 2.2e-07 30.2 0.2 2.7 2 0 0 2 2 2 1 Cupin domain AAA_2 PF07724.9 ETS60685.1 - 8.8e-34 116.8 0.0 3.6e-33 114.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 ETS60685.1 - 5.9e-13 49.1 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS60685.1 - 1.6e-07 31.4 0.0 6.9e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS60685.1 - 2.9e-06 27.4 0.0 1.3e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS60685.1 - 2.7e-05 23.8 0.0 7.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS60685.1 - 3.7e-05 24.5 0.0 7.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ClpB_D2-small PF10431.4 ETS60685.1 - 4.5e-05 23.2 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 2 C-terminal, D2-small domain, of ClpB protein MCM PF00493.18 ETS60685.1 - 5.2e-05 22.2 0.0 9.3e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_33 PF13671.1 ETS60685.1 - 0.00026 20.8 0.1 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS60685.1 - 0.0024 18.1 0.0 0.0064 16.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 ETS60685.1 - 0.0047 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETS60685.1 - 0.0052 16.4 0.1 0.017 14.7 0.0 2.0 1 1 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.13 ETS60685.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 ETS60685.1 - 0.014 14.8 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 ETS60685.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETS60685.1 - 0.02 14.3 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 ETS60685.1 - 0.024 13.7 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 ETS60685.1 - 0.04 13.8 0.0 0.16 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS60685.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETS60685.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 ETS60685.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 ETS60685.1 - 0.05 12.5 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.6 ETS60685.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETS60685.1 - 0.075 12.4 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain G-alpha PF00503.15 ETS60685.1 - 0.083 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 ETS60685.1 - 0.17 11.1 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 ETS60685.1 - 0.2 11.4 0.0 0.2 11.4 0.0 4.3 5 0 0 5 5 4 0 Part of AAA domain Pox_A32 PF04665.7 ETS60685.1 - 0.22 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.1 ETS60685.1 - 0.38 11.0 0.0 0.6 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DNA_ligase_A_M PF01068.16 ETS60686.1 - 2.4e-56 190.3 0.0 4e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ETS60686.1 - 7.7e-53 178.9 0.1 1.2e-52 178.2 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 ETS60686.1 - 3e-24 85.2 0.0 7.9e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Sigma70_ner PF04546.8 ETS60686.1 - 0.0083 15.7 0.8 0.016 14.8 0.5 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region DNA_ligase_OB_2 PF14743.1 ETS60686.1 - 0.025 14.2 0.2 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain RE_LlaMI PF09562.5 ETS60686.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 LlaMI restriction endonuclease eIF-3c_N PF05470.7 ETS60686.1 - 0.1 10.6 0.1 0.16 10.0 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nucleoplasmin PF03066.10 ETS60686.1 - 3.9 6.9 8.8 7.4 6.0 6.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin TRAPPC10 PF12584.3 ETS60687.1 - 2.7e-22 78.8 0.2 5e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Mito_carr PF00153.22 ETS60688.1 - 1.7e-71 236.0 1.0 1.7e-25 88.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EOS1 PF12326.3 ETS60689.1 - 1e-17 64.1 0.0 2.7e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 N-glycosylation protein MutS_V PF00488.16 ETS60690.1 - 1.5e-77 260.2 0.0 2.3e-77 259.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS60690.1 - 1.4e-49 168.6 5.9 2.2e-49 167.9 4.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 ETS60690.1 - 5.1e-20 71.6 0.0 1.1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 ETS60690.1 - 4.9e-08 33.1 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 ETS60690.1 - 0.0045 17.3 0.1 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS60690.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain tRNA-synt_1b PF00579.20 ETS60691.1 - 1.7e-61 207.9 0.0 3.9e-61 206.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF913 PF06025.7 ETS60691.1 - 0.14 10.8 0.4 0.22 10.2 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hexapep PF00132.19 ETS60692.1 - 2.6e-12 45.6 7.7 5.3e-10 38.3 3.1 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS60692.1 - 3.8e-12 45.5 5.8 8.9e-10 37.9 2.2 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 ETS60692.1 - 1.8e-09 37.4 0.2 6.8e-09 35.6 0.2 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase Amino_oxidase PF01593.19 ETS60693.1 - 3.5e-46 158.2 4.5 1.9e-44 152.4 3.1 2.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS60693.1 - 2.3e-12 46.7 0.3 8.9e-12 44.8 0.2 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS60693.1 - 1.1e-10 41.0 0.3 2e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS60693.1 - 5.8e-10 38.1 0.5 2.4e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 ETS60693.1 - 1.4e-08 34.0 0.1 2.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS60693.1 - 3.5e-08 33.7 0.4 7e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS60693.1 - 1.3e-07 31.7 0.0 2.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS60693.1 - 5.9e-07 28.8 0.2 1e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS60693.1 - 9.8e-07 29.0 0.0 5.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS60693.1 - 4.3e-06 26.0 0.1 8.1e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS60693.1 - 4.6e-06 25.9 1.1 6.2e-05 22.2 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS60693.1 - 1.4e-05 24.1 0.5 0.00014 20.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 ETS60693.1 - 0.00022 20.2 0.1 0.00022 20.2 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 ETS60693.1 - 0.00024 20.9 0.3 0.012 15.3 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Gti1_Pac2 PF09729.4 ETS60695.1 - 2.3e-57 193.5 0.0 2.3e-57 193.5 0.0 5.0 5 0 0 5 5 5 1 Gti1/Pac2 family HSA PF07529.8 ETS60695.1 - 6.1e-18 64.3 4.0 6.1e-18 64.3 2.8 4.7 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 ETS60695.1 - 4.4e-07 29.9 0.2 4.4e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Exo_endo_phos PF03372.18 ETS60697.1 - 4.3e-13 49.7 0.1 8.6e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SR-25 PF10500.4 ETS60697.1 - 0.36 10.2 13.9 0.11 11.9 4.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Syja_N PF02383.13 ETS60698.1 - 5.1e-91 304.7 0.0 7.6e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain CbiN PF02553.10 ETS60698.1 - 0.072 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Cobalt transport protein component CbiN zf-met PF12874.2 ETS60699.1 - 1.2e-06 28.5 1.2 3e-06 27.2 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 ETS60699.1 - 0.11 11.7 1.2 0.22 10.8 0.8 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Proteasome PF00227.21 ETS60700.1 - 1.7e-28 99.1 0.0 2e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 ETS60700.1 - 0.015 14.9 0.1 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Phyto_Pns9_10 PF05878.6 ETS60700.1 - 0.034 13.1 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Cu-oxidase_3 PF07732.10 ETS60701.1 - 1e-44 151.0 1.8 1.3e-43 147.5 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS60701.1 - 3.1e-32 110.9 10.7 1.1e-25 89.7 1.1 4.2 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase PF00394.17 ETS60701.1 - 2.3e-27 95.8 0.0 6.7e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase LAG1-DNAbind PF09271.6 ETS60702.1 - 1.4e-25 90.3 0.1 4.3e-24 85.5 0.1 2.5 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 ETS60702.1 - 2.3e-17 63.2 0.0 4.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF3545 PF12065.3 ETS60702.1 - 0.22 11.3 0.1 0.49 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Rad60-SLD PF11976.3 ETS60703.1 - 7.9e-27 92.7 0.5 9.2e-27 92.5 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETS60703.1 - 3.2e-13 48.8 0.1 4e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF4115 PF13464.1 ETS60703.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4115) DUF759 PF05537.6 ETS60704.1 - 0.056 12.2 0.0 0.059 12.1 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Spidroin_MaSp PF11260.3 ETS60704.1 - 0.13 12.3 2.6 0.16 12.0 1.8 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Pardaxin PF07425.6 ETS60704.1 - 0.29 10.5 11.3 2 7.8 3.0 3.1 1 1 1 2 2 2 0 Pardaxin SseC PF04888.7 ETS60704.1 - 0.53 9.5 6.4 0.9 8.8 4.4 1.5 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Antimicrobial_8 PF08103.6 ETS60704.1 - 1.2 9.2 4.8 3.7 7.6 0.2 3.0 1 1 2 3 3 3 0 Uperin family Coiled PF05710.7 ETS60704.1 - 9.2 6.8 10.2 20 5.7 7.1 1.8 1 1 0 1 1 1 0 Coiled coil TPR_11 PF13414.1 ETS60705.1 - 4.5e-48 160.7 39.1 6.7e-16 57.6 0.8 6.7 3 3 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 ETS60705.1 - 9.2e-37 123.1 19.6 4.2e-06 26.1 0.0 10.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETS60705.1 - 3.2e-33 110.9 21.5 0.00013 21.6 0.6 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETS60705.1 - 5.8e-21 74.6 21.6 0.00017 22.1 0.1 6.8 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETS60705.1 - 3.6e-20 71.6 17.1 3.1e-05 23.8 0.7 6.4 4 2 4 8 8 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETS60705.1 - 4.2e-18 63.9 11.4 0.0051 16.9 0.0 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS60705.1 - 6.2e-17 60.0 14.8 0.0031 17.1 0.0 9.7 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETS60705.1 - 2.3e-13 49.4 20.4 0.43 11.3 0.1 11.2 6 4 7 13 13 11 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETS60705.1 - 5.7e-12 44.4 9.4 0.016 14.9 0.0 7.7 7 1 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS60705.1 - 1.5e-11 44.2 14.1 0.041 14.0 0.3 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS60705.1 - 3.2e-09 36.9 20.4 0.00057 20.1 1.0 6.3 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 ETS60705.1 - 7.7e-07 28.8 0.4 0.0012 18.6 0.0 5.5 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS60705.1 - 0.0087 15.9 4.4 16 5.6 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltrans_RNA PF04452.9 ETS60705.1 - 0.09 11.8 2.5 0.16 11.1 0.2 2.2 2 0 0 2 2 2 0 RNA methyltransferase SHNi-TPR PF10516.4 ETS60705.1 - 0.23 10.7 7.5 9.5 5.5 0.0 4.7 5 0 0 5 5 5 0 SHNi-TPR TPR_6 PF13174.1 ETS60705.1 - 0.25 11.8 25.9 14 6.3 0.1 8.6 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETS60705.1 - 0.59 9.9 7.4 1.1 9.1 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PALP PF00291.20 ETS60706.1 - 3.2e-51 174.3 1.7 1.9e-50 171.8 1.2 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.2 ETS60706.1 - 0.027 14.3 0.3 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family ABC_trans_N PF14510.1 ETS60706.1 - 0.027 14.5 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Abhydrolase_5 PF12695.2 ETS60706.1 - 0.035 13.8 0.6 0.11 12.2 0.4 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Complex1_LYR_2 PF13233.1 ETS60707.1 - 1.2e-12 48.2 1.2 1.2e-12 48.1 0.1 1.6 2 0 0 2 2 2 1 Complex1_LYR-like PLDc_3 PF13918.1 ETS60707.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain Gluconate_2-dh3 PF13618.1 ETS60708.1 - 0.0015 18.6 0.5 0.0015 18.6 0.3 1.8 2 0 0 2 2 2 1 Gluconate 2-dehydrogenase subunit 3 Nucleoplasmin PF03066.10 ETS60708.1 - 0.016 14.7 0.9 0.023 14.2 0.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 ETS60708.1 - 0.039 14.0 4.2 0.08 13.0 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 ETS60708.1 - 0.083 13.2 4.6 0.073 13.3 2.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 ETS60708.1 - 0.16 11.5 6.8 0.06 12.9 1.9 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2347 PF09804.4 ETS60709.1 - 7e-41 140.3 0.0 2.6e-39 135.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 ETS60709.1 - 0.024 14.6 1.3 0.037 14.0 0.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 ETS60709.1 - 0.16 10.4 0.0 0.52 8.7 0.0 1.8 1 1 0 1 1 1 0 Transport protein Avl9 Mito_carr PF00153.22 ETS60710.1 - 9.2e-67 220.8 6.0 2.1e-23 81.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Evr1_Alr PF04777.8 ETS60711.1 - 2.4e-29 101.1 0.1 1.3e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 Erv1 / Alr family COX16 PF14138.1 ETS60711.1 - 1.2e-26 92.7 0.2 2e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 ACPS PF01648.15 ETS60712.1 - 9e-29 99.6 0.0 2.2e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PLA2_B PF01735.13 ETS60712.1 - 1.3e-16 59.8 0.0 1.7e-12 46.3 0.1 3.0 3 0 0 3 3 3 3 Lysophospholipase catalytic domain Longin PF13774.1 ETS60714.1 - 9.1e-27 92.4 0.1 1.7e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 ETS60714.1 - 5.3e-11 41.9 0.2 1.3e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 Synaptobrevin DEAD PF00270.24 ETS60714.1 - 2.3e-10 40.2 0.0 5.1e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS60714.1 - 6.2e-05 22.7 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1664 PF07889.7 ETS60714.1 - 0.21 11.3 1.3 0.28 10.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BTB_2 PF02214.17 ETS60715.1 - 0.00017 21.7 0.0 0.017 15.2 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain Ribosomal_S10 PF00338.17 ETS60716.1 - 2.1e-22 78.7 0.0 3.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkinase_C PF00433.19 ETS60717.1 - 0.013 16.0 0.8 0.32 11.5 0.3 3.3 2 0 0 2 2 2 0 Protein kinase C terminal domain FAM117 PF15388.1 ETS60719.1 - 3.1 6.9 15.8 3.4 6.7 10.1 1.6 2 0 0 2 2 2 0 Protein Family FAM117 DUF1708 PF08101.6 ETS60720.1 - 2.9e-20 72.4 0.8 2.3e-16 59.6 0.5 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 ETS60720.1 - 1.5e-06 27.9 0.0 2e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain FA_hydroxylase PF04116.8 ETS60721.1 - 8.6e-16 58.3 18.2 8.6e-16 58.3 12.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Bromodomain PF00439.20 ETS60722.1 - 1e-21 76.6 0.0 2e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain TrbI PF03743.9 ETS60722.1 - 0.099 12.1 2.5 0.11 11.9 0.5 2.1 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein CDC45 PF02724.9 ETS60722.1 - 2.5 6.0 24.4 0.26 9.2 0.8 2.5 2 0 0 2 2 2 0 CDC45-like protein WD40 PF00400.27 ETS60723.1 - 3e-56 185.4 11.2 5.4e-09 35.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 ETS60723.1 - 0.0061 16.0 0.3 0.95 8.8 0.2 2.6 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 ETS60723.1 - 0.045 11.8 0.8 8.1 4.4 0.0 3.2 2 1 2 4 4 4 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 ETS60723.1 - 0.11 12.8 1.0 25 5.3 0.2 3.3 3 0 0 3 3 3 0 PQQ-like domain TFIIS_M PF07500.9 ETS60724.1 - 1.9e-29 102.0 1.3 1.9e-29 102.0 0.9 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 ETS60724.1 - 5.3e-19 67.5 9.2 8.1e-19 66.9 6.4 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 ETS60724.1 - 1.2e-13 50.3 0.1 3.6e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zinc_ribbon_5 PF13719.1 ETS60724.1 - 0.051 13.1 4.2 0.11 12.0 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain HTH_22 PF13309.1 ETS60724.1 - 0.059 13.1 0.3 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 HTH domain Myc_target_1 PF15179.1 ETS60724.1 - 0.068 12.7 1.8 0.13 11.8 1.2 1.4 1 0 0 1 1 1 0 Myc target protein 1 zinc_ribbon_4 PF13717.1 ETS60724.1 - 0.1 12.2 4.3 0.23 11.1 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF1180 PF06679.7 ETS60724.1 - 6.9 6.5 8.5 3.6 7.4 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Ammonium_transp PF00909.16 ETS60725.1 - 1.3e-112 376.2 29.9 1.5e-112 376.0 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YuiB PF14068.1 ETS60725.1 - 6.6 7.1 10.2 0.99 9.7 3.8 2.2 2 0 0 2 2 2 0 Putative membrane protein MRP-S28 PF10213.4 ETS60726.1 - 1.5e-38 131.7 0.1 2.1e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein AAA_33 PF13671.1 ETS60727.1 - 4.7e-15 55.7 0.5 2.7e-14 53.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 ETS60727.1 - 4.3e-07 29.9 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 ETS60727.1 - 1.9e-05 25.4 0.0 2.7e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS60727.1 - 2.8e-05 24.2 0.0 8.5e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS60727.1 - 0.0017 18.7 0.1 0.0055 17.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 ETS60727.1 - 0.0036 16.9 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 ETS60727.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 ETS60727.1 - 0.026 13.4 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 ETS60727.1 - 0.027 14.4 0.4 0.055 13.4 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETS60727.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 ETS60727.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 ETS60727.1 - 0.058 12.9 0.1 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 ETS60727.1 - 0.068 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.12 ETS60727.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SIR2 PF02146.12 ETS60728.1 - 3.1e-53 180.1 0.0 4.6e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family adh_short PF00106.20 ETS60729.1 - 2.2e-29 102.5 0.2 2.9e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS60729.1 - 1.6e-14 54.2 0.0 1.9e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS60729.1 - 2.6e-09 37.0 0.1 4.2e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETS60729.1 - 0.0001 21.5 0.0 0.00048 19.3 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 ETS60729.1 - 0.00011 22.2 0.1 0.00037 20.5 0.0 1.8 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETS60729.1 - 0.00016 21.1 0.0 0.00035 20.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS60729.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lactamase_B_2 PF12706.2 ETS60730.1 - 5.4e-30 104.3 0.2 9.1e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS60730.1 - 5.6e-07 29.4 0.1 1.1e-05 25.1 0.1 2.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain A_deamin PF02137.13 ETS60731.1 - 4.6e-51 174.1 0.0 6e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain F-box-like PF12937.2 ETS60732.1 - 0.0091 15.7 0.1 0.089 12.5 0.0 2.6 2 1 0 2 2 2 1 F-box-like Peptidase_M20 PF01546.23 ETS60733.1 - 3.5e-24 85.3 0.1 5.5e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS60733.1 - 1.1e-11 44.4 0.0 3.5e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS60733.1 - 0.042 13.5 0.1 0.1 12.2 0.1 1.7 1 1 0 1 1 1 0 Peptidase family M28 DUF4256 PF14066.1 ETS60733.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) DER1 PF04511.10 ETS60734.1 - 1.2e-31 109.7 0.1 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Der1-like family zf-CCHC PF00098.18 ETS60735.1 - 3.6e-14 51.8 21.4 9.4e-05 22.1 1.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 ETS60735.1 - 1.4e-06 27.8 23.1 0.01 15.4 0.5 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 ETS60735.1 - 2.6e-06 26.8 13.6 0.0049 16.3 0.8 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.1 ETS60735.1 - 0.048 13.3 0.5 0.048 13.3 0.3 3.4 3 0 0 3 3 3 0 Zinc knuckle Sar8_2 PF03058.9 ETS60735.1 - 8.2 6.8 6.5 24 5.3 0.1 2.7 1 1 1 2 2 2 0 Sar8.2 family Methyltransf_31 PF13847.1 ETS60736.1 - 1.3e-11 44.3 0.1 1.8e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS60736.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 ETS60736.1 - 3.5e-09 37.2 0.0 9.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60736.1 - 1e-07 32.3 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS60736.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 ETS60736.1 - 1.3e-07 30.9 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 ETS60736.1 - 2.8e-06 27.3 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS60736.1 - 8.1e-06 26.2 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 ETS60736.1 - 3.7e-05 22.5 0.0 5.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 ETS60736.1 - 0.00012 22.3 0.0 0.00026 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS60736.1 - 0.00019 20.8 0.2 0.00042 19.7 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 ETS60736.1 - 0.00047 19.3 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 ETS60736.1 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 ETS60736.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 ETS60736.1 - 0.099 12.0 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 ETS60736.1 - 0.11 13.3 0.0 0.31 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 ETS60736.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 ETS60736.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.10 ETS60736.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 V-SNARE_C PF12352.3 ETS60737.1 - 1e-15 57.4 0.5 2.7e-15 56.1 0.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETS60737.1 - 3.5e-06 26.6 0.0 1.1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Sec20 Mito_fiss_reg PF05308.6 ETS60737.1 - 0.0037 16.6 0.5 0.0046 16.3 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator V-SNARE PF05008.10 ETS60737.1 - 0.035 14.2 0.4 0.085 13.0 0.3 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Wbp11 PF09429.5 ETS60737.1 - 0.34 10.8 2.1 0.84 9.6 0.4 2.2 2 1 1 3 3 3 0 WW domain binding protein 11 Oxidored_q6 PF01058.17 ETS60738.1 - 4.6e-21 74.7 0.1 7.1e-21 74.1 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit WD40 PF00400.27 ETS60740.1 - 1e-14 53.7 11.4 7.2e-06 25.6 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat DPPIV_N PF00930.16 ETS60740.1 - 0.018 13.6 0.5 0.83 8.1 0.4 2.5 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Rax2 PF12768.2 ETS60740.1 - 0.044 12.9 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DAP3 PF10236.4 ETS60741.1 - 3.2e-72 243.0 0.9 4.3e-72 242.6 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 ETS60741.1 - 6e-08 32.6 0.1 4.1e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 ETS60741.1 - 1.5e-07 31.6 0.9 1.5e-07 31.6 0.7 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS60741.1 - 3.7e-05 23.8 0.7 0.00079 19.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS60741.1 - 0.0013 18.1 0.5 0.003 16.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS60741.1 - 0.0055 16.4 0.0 0.023 14.4 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain Helicase_RecD PF05127.9 ETS60741.1 - 0.012 15.2 3.8 0.018 14.6 0.0 2.9 3 1 0 3 3 3 0 Helicase AAA_14 PF13173.1 ETS60741.1 - 0.034 14.0 0.1 0.34 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain PEP-utilizers PF00391.18 ETS60741.1 - 0.094 12.2 1.5 12 5.5 0.0 3.6 4 0 0 4 4 4 0 PEP-utilising enzyme, mobile domain Myosin_tail_1 PF01576.14 ETS60742.1 - 0.057 11.1 31.9 0.0083 13.9 9.4 3.3 3 1 0 3 3 3 0 Myosin tail DUF641 PF04859.7 ETS60742.1 - 0.17 11.6 12.0 0.41 10.4 0.5 3.8 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Spc7 PF08317.6 ETS60742.1 - 5 5.6 15.1 1.8 7.1 0.6 2.9 3 0 0 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 ETS60742.1 - 8.1 5.9 23.6 0.18 11.3 1.4 3.3 2 1 0 2 2 2 0 IncA protein PX PF00787.19 ETS60743.1 - 2.5e-25 88.4 0.1 3.6e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 PX domain TMF_DNA_bd PF12329.3 ETS60744.1 - 0.00079 19.1 5.1 0.00079 19.1 3.6 2.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 ETS60744.1 - 6.7 5.5 12.6 12 4.7 8.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 XPG_N PF00752.12 ETS60745.1 - 4.1e-35 120.0 0.0 8.7e-35 119.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 ETS60745.1 - 3.8e-29 100.5 0.1 1.1e-28 99.1 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 ETS60745.1 - 1.3e-08 35.0 0.1 4e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 ETS60745.1 - 0.026 14.6 0.0 0.08 13.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4192 PF13830.1 ETS60745.1 - 0.036 13.7 0.4 0.67 9.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DNA_pol_lambd_f PF10391.4 ETS60745.1 - 0.075 12.5 0.0 0.27 10.8 0.0 2.0 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda PNGaseA PF12222.3 ETS60746.1 - 5.9e-64 216.4 0.0 1e-62 212.4 0.0 2.1 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A COQ7 PF03232.8 ETS60747.1 - 5.1e-63 211.6 0.1 5.2e-62 208.3 0.1 2.1 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 FAD_binding_3 PF01494.14 ETS60747.1 - 4.3e-14 52.3 6.5 1.1e-08 34.6 0.1 3.3 3 0 0 3 3 3 2 FAD binding domain SE PF08491.5 ETS60747.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 ETS60747.1 - 0.018 15.3 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS60747.1 - 0.035 13.8 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Hpt PF01627.18 ETS60747.1 - 0.2 11.6 2.4 3.2 7.8 0.1 3.1 2 1 0 2 2 2 0 Hpt domain Cyclin PF08613.6 ETS60748.1 - 9e-14 52.1 0.0 3.9e-12 46.8 0.0 2.6 2 1 0 2 2 2 1 Cyclin Pkinase PF00069.20 ETS60749.1 - 5.5e-30 104.3 0.0 1.7e-29 102.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60749.1 - 2.2e-14 53.1 0.0 4.6e-14 52.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase FAD_binding_7 PF03441.9 ETS60750.1 - 4.6e-62 209.7 1.5 6.3e-62 209.2 1.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS60750.1 - 2.6e-22 79.3 0.0 5.8e-22 78.1 0.0 1.5 1 1 0 1 1 1 1 DNA photolyase HSP70 PF00012.15 ETS60751.1 - 1.6e-160 534.9 0.7 2.4e-160 534.3 0.5 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS60751.1 - 4.9e-12 45.0 0.0 1.3e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein Aldedh PF00171.17 ETS60752.1 - 1.2e-13 50.2 6.5 6.3e-12 44.5 3.4 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L34 PF00468.12 ETS60753.1 - 1.3e-15 56.8 9.6 2e-15 56.1 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 ATP-synt_C PF00137.16 ETS60754.1 - 4.6e-28 96.9 33.9 2.3e-17 62.6 8.4 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 ETS60754.1 - 0.77 9.3 7.9 0.26 10.9 1.8 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Dus PF01207.12 ETS60755.1 - 1.9e-46 158.3 0.0 2e-31 109.0 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF3487 PF11990.3 ETS60755.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF155 PF02582.9 ETS60756.1 - 2e-51 174.3 0.3 4e-51 173.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Nucleoplasmin PF03066.10 ETS60756.1 - 0.99 8.9 13.8 2.5 7.6 9.5 1.7 1 0 0 1 1 1 0 Nucleoplasmin MPLKIP PF15502.1 ETS60757.1 - 0.065 13.9 7.1 0.11 13.2 4.8 1.6 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein Prenyltrans_2 PF13249.1 ETS60758.1 - 2.9e-41 140.4 8.7 8.8e-18 64.7 0.2 5.3 3 3 3 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 ETS60758.1 - 1.8e-33 113.7 6.7 1.8e-09 36.9 0.1 6.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 ETS60758.1 - 6.3e-27 93.7 0.5 6.6e-13 48.6 0.5 5.4 3 2 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 ETS60758.1 - 2e-08 33.7 0.3 0.32 10.1 0.0 4.9 2 1 3 5 5 5 4 Pectic acid lyase A2M_comp PF07678.9 ETS60758.1 - 0.0016 17.7 0.4 2.7 7.1 0.0 3.8 3 1 0 3 3 3 1 A-macroglobulin complement component DUF1925 PF09094.6 ETS60758.1 - 0.02 14.8 0.1 11 6.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) DUF1242 PF06842.7 ETS60759.1 - 1.2e-17 63.0 0.4 1.6e-17 62.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) GST_N_3 PF13417.1 ETS60760.1 - 6e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS60760.1 - 7.5e-10 38.8 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS60760.1 - 1.5e-09 37.6 0.0 4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS60760.1 - 2.4e-09 36.9 0.0 6.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS60760.1 - 1.3e-07 31.5 0.0 3.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS60760.1 - 0.00016 22.1 0.8 0.00078 19.8 0.1 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain Sua5_yciO_yrdC PF01300.13 ETS60761.1 - 6.9e-49 165.5 0.1 2.7e-48 163.5 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 ETS60761.1 - 2.5e-26 92.1 0.0 7.5e-26 90.6 0.0 1.8 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Pkinase PF00069.20 ETS60762.1 - 5e-68 229.0 0.0 7.1e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60762.1 - 2.8e-56 190.4 0.0 4.4e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 ETS60762.1 - 1.1e-07 31.3 6.8 1.9e-07 30.7 4.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 ETS60762.1 - 2.1e-05 24.4 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 ETS60762.1 - 3.2e-05 23.8 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin Kinase-like PF14531.1 ETS60762.1 - 8.2e-05 21.6 0.0 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 ETS60762.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 ETS60762.1 - 0.0091 14.8 0.2 0.015 14.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Prok-RING_1 PF14446.1 ETS60762.1 - 0.02 14.5 7.8 0.039 13.7 5.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CAMSAP_CH PF11971.3 ETS60762.1 - 0.034 13.7 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain PHD PF00628.24 ETS60762.1 - 0.18 11.5 7.7 0.33 10.6 5.3 1.4 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 ETS60765.1 - 2.9e-47 156.9 22.1 9.6e-11 41.1 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 ETS60765.1 - 0.0045 16.7 6.8 0.41 10.3 0.6 3.8 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term EamA PF00892.15 ETS60766.1 - 1.7e-26 92.7 32.0 2.2e-15 56.8 5.9 3.1 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 ETS60766.1 - 2.3e-06 27.7 4.7 2.3e-06 27.7 3.2 3.3 2 2 0 3 3 3 2 Multidrug resistance efflux transporter DUF1469 PF07332.6 ETS60766.1 - 0.0069 16.1 3.1 0.0069 16.1 2.1 4.5 3 1 2 5 5 5 1 Protein of unknown function (DUF1469) TPT PF03151.11 ETS60766.1 - 0.25 10.9 17.7 0.23 11.1 3.5 3.2 2 1 0 2 2 2 0 Triose-phosphate Transporter family Fungal_trans PF04082.13 ETS60767.1 - 7.3e-14 51.2 0.1 1.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS60767.1 - 1.8e-06 27.7 9.7 3.7e-06 26.7 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_6 PF13344.1 ETS60768.1 - 5.1e-10 39.1 0.0 9.1e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS60768.1 - 3.6e-06 26.6 0.0 3.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like TIR_2 PF13676.1 ETS60768.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 TIR domain Hexapep PF00132.19 ETS60769.1 - 2.1e-10 39.5 13.5 1e-05 24.8 1.9 4.6 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS60769.1 - 6.9e-06 25.5 13.1 0.00014 21.3 1.2 3.9 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 ETS60769.1 - 0.0066 15.0 0.1 0.011 14.3 0.1 1.3 1 0 0 1 1 1 1 L-fucokinase Sec1 PF00995.18 ETS60770.1 - 2.8e-150 501.6 0.0 3.2e-150 501.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Hexapep PF00132.19 ETS60771.1 - 2.6e-05 23.4 4.3 0.00064 19.1 1.2 3.3 1 1 2 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 ETS60771.1 - 9.8e-05 22.4 0.1 0.00026 21.1 0.1 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 ETS60771.1 - 0.0088 15.5 5.5 0.27 10.8 3.8 2.5 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 ETS60771.1 - 0.021 14.1 0.0 0.11 11.8 0.1 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase CTP_transf_3 PF02348.14 ETS60771.1 - 0.045 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase Aa_trans PF01490.13 ETS60772.1 - 3.3e-73 246.5 17.1 3.3e-73 246.5 11.9 1.7 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 ETS60772.1 - 0.00038 19.4 10.6 0.00038 19.4 7.3 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SR-25 PF10500.4 ETS60773.1 - 5.3 6.4 8.9 10 5.5 6.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PACT_coil_coil PF10495.4 ETS60774.1 - 1.4e-09 37.6 0.5 6.6e-09 35.5 0.3 2.3 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Lebercilin PF15619.1 ETS60774.1 - 0.0036 16.7 12.5 0.0036 16.7 8.7 6.8 3 2 2 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease DUF4140 PF13600.1 ETS60774.1 - 0.0056 17.1 6.4 0.0056 17.1 4.4 12.5 2 2 11 14 14 14 2 N-terminal domain of unknown function (DUF4140) Vac_Fusion PF02346.11 ETS60774.1 - 0.099 12.0 4.0 0.14 11.6 0.1 3.3 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Reo_sigmaC PF04582.7 ETS60774.1 - 0.68 9.0 23.0 0.48 9.5 0.8 5.0 2 2 3 6 6 6 0 Reovirus sigma C capsid protein Zn_clus PF00172.13 ETS60775.1 - 1.6e-06 27.9 10.2 1.6e-06 27.9 7.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 ETS60775.1 - 0.00012 22.2 0.0 0.00056 20.1 0.0 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS60775.1 - 0.0022 18.1 0.1 0.0022 18.1 0.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2530 PF10745.4 ETS60775.1 - 0.039 13.9 0.4 0.092 12.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) ABC_membrane PF00664.18 ETS60776.1 - 3.6e-43 147.9 2.3 6.3e-43 147.1 1.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 ETS60776.1 - 3.4e-32 111.5 0.0 7.5e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.4 ETS60776.1 - 0.0012 17.5 0.0 0.0018 16.9 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_21 PF13304.1 ETS60776.1 - 0.003 17.5 0.0 0.33 10.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETS60776.1 - 0.0032 16.7 0.0 0.058 12.6 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS60776.1 - 0.043 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 ETS60776.1 - 0.045 13.1 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain CLASP_N PF12348.3 ETS60777.1 - 3.4e-25 88.7 0.0 5.1e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal CBF PF03914.12 ETS60778.1 - 4.4e-42 143.3 0.0 2.4e-41 140.9 0.0 2.4 1 0 0 1 1 1 1 CBF/Mak21 family Adaptin_N PF01602.15 ETS60778.1 - 0.012 13.9 0.2 0.98 7.6 0.0 2.6 3 1 0 3 3 3 0 Adaptin N terminal region vMSA PF00695.14 ETS60778.1 - 2.3 7.3 5.3 5.3 6.1 3.7 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Peptidase_C15 PF01470.12 ETS60779.1 - 5.5e-10 39.4 0.0 0.00026 20.8 0.0 2.4 2 1 0 2 2 2 2 Pyroglutamyl peptidase DUF3899 PF13038.1 ETS60780.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) DUF2721 PF11026.3 ETS60780.1 - 0.042 13.4 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Ibs_toxin PF13956.1 ETS60780.1 - 1.1 9.1 4.6 2 8.2 3.2 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Pkinase PF00069.20 ETS60781.1 - 2.4e-64 216.9 0.0 3.2e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60781.1 - 1.7e-44 151.8 0.0 2.5e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60781.1 - 3.6e-08 32.7 0.0 8.6e-08 31.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 ETS60781.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family UCH PF00443.24 ETS60783.1 - 1.5e-43 148.8 0.0 1.9e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS60783.1 - 2.7e-17 63.1 0.0 4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pantoate_ligase PF02569.10 ETS60783.1 - 0.26 10.0 0.3 0.54 8.9 0.2 1.4 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase DnaJ-X PF14308.1 ETS60784.1 - 7.5e-43 146.1 4.2 8.3e-43 146.0 2.0 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 ETS60784.1 - 3.3e-26 90.7 1.8 1e-25 89.2 1.3 1.9 1 0 0 1 1 1 1 DnaJ domain ATG16 PF08614.6 ETS60784.1 - 0.0057 16.4 1.3 0.0057 16.4 0.9 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) OmdA PF13376.1 ETS60784.1 - 0.038 13.6 2.5 0.15 11.7 1.8 2.1 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Las1 PF04031.8 ETS60785.1 - 1.2e-47 161.4 1.4 1.7e-47 160.9 0.2 1.8 2 0 0 2 2 2 1 Las1-like Pet127 PF08634.5 ETS60790.1 - 8.1e-113 376.1 0.2 1.1e-112 375.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 CAF-1_p150 PF11600.3 ETS60790.1 - 0.38 10.0 6.9 0.97 8.7 4.7 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_L6e PF01159.14 ETS60791.1 - 2.1e-38 130.8 1.1 2.1e-38 130.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 ETS60791.1 - 0.0022 17.8 0.5 0.0022 17.8 0.3 2.5 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain Thi4 PF01946.12 ETS60793.1 - 4.3e-93 310.6 0.2 5.2e-93 310.3 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 ETS60793.1 - 1.7e-07 30.4 1.2 9.6e-07 28.0 0.6 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS60793.1 - 5.2e-07 29.5 0.2 1.5e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS60793.1 - 1.1e-06 27.8 0.4 5.1e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS60793.1 - 9.6e-06 25.6 0.1 3.1e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS60793.1 - 1.2e-05 24.3 1.2 0.00015 20.7 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 ETS60793.1 - 1.9e-05 24.4 0.2 0.0004 20.2 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 ETS60793.1 - 0.00049 18.6 0.2 0.00073 18.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 ETS60793.1 - 0.0032 17.5 0.5 0.013 15.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS60793.1 - 0.01 14.5 0.2 0.015 13.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 ETS60793.1 - 0.051 12.4 0.0 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS60793.1 - 0.11 11.6 1.5 0.2 10.6 1.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Xpo1 PF08389.7 ETS60794.1 - 7.5e-19 68.1 1.4 5.4e-16 58.8 0.0 4.4 6 0 0 6 6 6 1 Exportin 1-like protein HEAT PF02985.17 ETS60794.1 - 0.0063 16.4 1.0 1.2 9.4 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat UME PF08064.8 ETS60794.1 - 0.098 12.6 0.1 1 9.3 0.0 2.7 2 0 0 2 2 2 0 UME (NUC010) domain HSF_DNA-bind PF00447.12 ETS60796.1 - 1.2e-20 73.6 0.0 2.2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PRP1_N PF06424.7 ETS60797.1 - 1.5e-43 148.2 3.1 1.5e-43 148.2 2.1 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 ETS60797.1 - 5.4e-24 82.4 43.4 0.029 14.9 0.7 13.9 7 6 7 14 14 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETS60797.1 - 9.8e-14 51.5 38.6 0.024 15.3 1.2 8.9 7 2 3 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 ETS60797.1 - 5.6e-13 49.0 23.5 0.0042 17.3 0.2 10.3 7 3 5 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS60797.1 - 9.2e-06 25.2 0.5 0.9 9.2 0.0 6.4 5 2 2 7 7 7 1 TPR repeat TPR_15 PF13429.1 ETS60797.1 - 7.2e-05 21.9 20.4 0.0012 17.9 0.6 5.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS60797.1 - 0.00062 19.4 0.9 8.4 6.5 0.0 7.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS60797.1 - 0.061 13.8 6.0 24 5.6 0.0 6.9 7 2 0 7 7 7 0 Tetratricopeptide repeat NRDE-2 PF08424.5 ETS60797.1 - 0.56 9.0 18.7 0.63 8.8 0.3 5.5 6 1 1 7 7 7 0 NRDE-2, necessary for RNA interference DER1 PF04511.10 ETS60798.1 - 1.7e-50 171.3 2.6 1.9e-50 171.1 1.8 1.0 1 0 0 1 1 1 1 Der1-like family DUF962 PF06127.6 ETS60799.1 - 2.3e-23 81.8 0.0 6e-23 80.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) GlpM PF06942.7 ETS60799.1 - 0.13 12.5 2.9 3.3 8.0 0.0 2.2 2 0 0 2 2 2 0 GlpM protein Nt_Gln_amidase PF09764.4 ETS60800.1 - 4e-31 107.7 0.2 9.4e-14 51.1 0.0 3.9 2 1 0 3 3 3 2 N-terminal glutamine amidase KAT11 PF08214.6 ETS60801.1 - 8.9e-30 103.9 0.0 4.1e-29 101.7 0.0 2.0 1 1 0 1 1 1 1 Histone acetylation protein NAD_synthase PF02540.12 ETS60801.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Na_H_Exchanger PF00999.16 ETS60802.1 - 7.4e-62 209.0 17.1 9.6e-62 208.6 11.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 ETS60802.1 - 0.052 13.4 0.6 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 YrhC-like protein XhlA PF10779.4 ETS60802.1 - 3.7 7.5 4.6 36 4.3 0.2 2.7 2 0 0 2 2 2 0 Haemolysin XhlA PIG-F PF06699.6 ETS60803.1 - 6.4e-13 49.0 2.0 6.4e-13 49.0 1.4 1.4 2 0 0 2 2 2 1 GPI biosynthesis protein family Pig-F Ish1 PF10281.4 ETS60804.1 - 1.5e-56 188.0 28.1 7.3e-11 41.9 0.1 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein LEM PF03020.10 ETS60804.1 - 0.0051 16.2 0.0 19 4.7 0.0 4.6 6 0 0 6 6 6 1 LEM domain APC2 PF08672.6 ETS60804.1 - 0.011 15.9 0.0 57 4.0 0.0 4.5 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 SAP PF02037.22 ETS60804.1 - 0.022 14.2 0.0 56 3.4 0.0 4.3 5 0 0 5 5 5 0 SAP domain TryThrA_C PF12319.3 ETS60804.1 - 0.073 12.2 6.9 0.033 13.3 2.8 1.9 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Macoilin PF09726.4 ETS60804.1 - 5.5 5.1 16.0 7.9 4.6 11.1 1.3 1 0 0 1 1 1 0 Transmembrane protein zf-Apc11 PF12861.2 ETS60805.1 - 1.8e-32 111.0 11.0 2.4e-32 110.6 7.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 ETS60805.1 - 1.3e-28 98.8 11.3 1.6e-28 98.5 7.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 ETS60805.1 - 7.1e-08 32.1 16.3 2.5e-07 30.4 11.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS60805.1 - 0.00026 20.9 12.0 0.01 15.8 7.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS60805.1 - 0.00059 19.4 13.3 0.0069 16.0 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS60805.1 - 0.00088 18.8 12.4 0.0039 16.8 8.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS60805.1 - 0.03 14.0 14.7 0.25 11.1 10.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Tax PF02959.11 ETS60805.1 - 0.072 12.5 1.7 0.088 12.2 1.2 1.1 1 0 0 1 1 1 0 HTLV Tax FANCL_C PF11793.3 ETS60805.1 - 0.56 10.2 13.5 2 8.4 9.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 ETS60805.1 - 0.6 10.1 8.7 0.71 9.8 5.6 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.1 ETS60805.1 - 0.62 9.7 16.5 4.1 7.0 8.6 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RRN7 PF11781.3 ETS60805.1 - 2.1 7.9 8.2 9.9 5.7 2.6 2.9 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HC5HC2H PF13771.1 ETS60805.1 - 2.7 8.2 10.9 2 8.6 6.2 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 ETS60805.1 - 9.2 6.3 13.4 30 4.7 9.3 2.0 1 1 0 1 1 1 0 RING-like domain UPF0183 PF03676.9 ETS60806.1 - 8.3e-29 100.3 1.2 9.1e-10 37.6 0.7 5.5 5 1 0 5 5 5 4 Uncharacterised protein family (UPF0183) DUF1664 PF07889.7 ETS60807.1 - 0.0027 17.4 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Syntaxin PF00804.20 ETS60807.1 - 0.0038 17.3 2.2 0.0076 16.3 1.5 1.4 1 0 0 1 1 1 1 Syntaxin HisKA PF00512.20 ETS60807.1 - 0.023 14.6 0.6 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain IL2 PF00715.12 ETS60807.1 - 0.041 13.6 0.2 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Interleukin 2 Syntaxin-6_N PF09177.6 ETS60807.1 - 0.06 13.7 0.5 0.19 12.1 0.2 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal H-kinase_dim PF02895.9 ETS60807.1 - 0.077 13.3 1.0 0.78 10.1 0.7 2.3 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Prominin PF05478.6 ETS60807.1 - 0.09 10.3 0.4 0.13 9.8 0.2 1.1 1 0 0 1 1 1 0 Prominin CHASE3 PF05227.8 ETS60807.1 - 0.13 11.9 4.0 0.073 12.7 0.8 2.0 2 1 0 2 2 2 0 CHASE3 domain FlaC_arch PF05377.6 ETS60807.1 - 0.26 11.2 0.9 0.79 9.6 0.1 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FlgN PF05130.7 ETS60807.1 - 0.35 11.1 4.7 0.095 12.9 0.9 1.7 2 0 0 2 2 2 0 FlgN protein DUF2203 PF09969.4 ETS60807.1 - 0.37 11.0 1.6 0.41 10.8 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF883 PF05957.8 ETS60807.1 - 2.8 8.3 11.6 2 8.8 3.1 2.7 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) G_glu_transpept PF01019.16 ETS60808.1 - 6.7e-154 513.1 0.0 8.2e-154 512.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3357 PF11837.3 ETS60808.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) RRM_1 PF00076.17 ETS60809.1 - 5.9e-38 128.3 0.0 2.2e-15 56.0 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60809.1 - 2.1e-34 117.3 0.0 1.2e-13 50.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60809.1 - 4.5e-16 58.4 0.0 1e-09 38.1 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS60809.1 - 0.034 13.9 0.0 0.72 9.7 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif Mitochondr_Som1 PF11093.3 ETS60813.1 - 8.7e-08 31.8 0.5 1.6e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PHD PF00628.24 ETS60815.1 - 6e-07 29.0 8.9 1.1e-06 28.1 6.2 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 ETS60815.1 - 0.034 13.8 4.6 0.069 12.8 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SAP30_Sin3_bdg PF13867.1 ETS60815.1 - 0.039 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-HC5HC2H PF13771.1 ETS60815.1 - 0.083 13.0 0.8 0.19 11.9 0.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4206 PF13901.1 ETS60815.1 - 0.46 9.9 4.5 0.91 9.0 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) RhoGEF PF00621.15 ETS60816.1 - 2.5e-18 66.6 0.0 5.1e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Malic_M PF03949.10 ETS60818.1 - 4.8e-80 268.7 0.0 6.7e-80 268.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 ETS60818.1 - 1e-66 223.9 0.0 1.5e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TPR_11 PF13414.1 ETS60819.1 - 2e-14 52.9 11.2 6.6e-13 48.1 4.6 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETS60819.1 - 5.2e-10 38.4 11.2 2.5e-05 23.6 0.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS60819.1 - 1.3e-08 34.1 14.3 0.0006 19.5 1.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS60819.1 - 6e-08 32.4 3.4 1.2e-07 31.4 2.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS60819.1 - 8.8e-08 31.9 12.0 4.2e-05 23.4 4.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat NYD-SP12_N PF15015.1 ETS60819.1 - 3.3e-06 25.6 0.6 4.2e-06 25.2 0.4 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_17 PF13431.1 ETS60819.1 - 6.1e-06 26.0 6.4 0.0018 18.3 0.6 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS60819.1 - 1.2e-05 25.4 5.9 0.013 16.1 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS60819.1 - 1.7e-05 24.2 2.9 0.045 13.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS60819.1 - 1.7e-05 25.3 10.9 0.00011 22.7 6.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS60819.1 - 4.9e-05 23.3 2.5 9.9e-05 22.4 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 ETS60819.1 - 0.00011 21.3 2.3 0.076 12.0 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS60819.1 - 0.0012 19.2 3.8 0.49 10.9 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS60819.1 - 0.0014 18.9 7.8 0.0045 17.3 4.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS60819.1 - 0.17 11.7 7.7 0.44 10.4 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS60819.1 - 0.25 11.3 0.2 0.25 11.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DSPc PF00782.15 ETS60821.1 - 5.6e-27 93.9 0.2 1.1e-26 92.9 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS60821.1 - 0.003 16.9 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 ETS60821.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 ETS60821.1 - 0.026 14.8 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family CUE PF02845.11 ETS60822.1 - 1.5e-10 40.3 0.0 2.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.6 ETS60822.1 - 0.05 13.5 0.1 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) zf-C2H2 PF00096.21 ETS60824.1 - 2.7e-07 30.5 16.2 0.00025 21.1 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS60824.1 - 3.7e-06 26.9 5.4 3.7e-06 26.9 3.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS60824.1 - 3.8e-05 23.7 10.5 0.0059 16.8 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS60824.1 - 3 8.1 9.3 25 5.1 3.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mg_trans_NIPA PF05653.9 ETS60825.1 - 7.5e-64 215.5 4.2 4.7e-61 206.3 1.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 ETS60825.1 - 9.3e-08 32.2 9.4 5.1e-06 26.6 0.1 2.8 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 ETS60825.1 - 0.00088 19.3 5.4 0.00088 19.3 3.7 3.7 3 1 1 4 4 4 1 EamA-like transporter family DUF1510 PF07423.6 ETS60825.1 - 0.035 13.4 0.1 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Macoilin PF09726.4 ETS60825.1 - 0.25 9.5 1.8 0.54 8.4 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein Zip PF02535.17 ETS60825.1 - 4.1 6.3 12.0 22 3.9 5.8 3.0 3 0 0 3 3 3 0 ZIP Zinc transporter Coprogen_oxidas PF01218.13 ETS60826.1 - 4e-110 367.0 4.5 2.5e-37 128.0 0.0 3.3 4 0 0 4 4 4 3 Coproporphyrinogen III oxidase Lactonase PF10282.4 ETS60828.1 - 7.6e-73 245.5 0.4 1e-72 245.1 0.3 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Trep_Strep PF09605.5 ETS60828.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Nup54 PF13874.1 ETS60829.1 - 1.6e-27 95.8 1.8 1.6e-27 95.8 1.2 2.8 4 0 0 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 ETS60829.1 - 6.3 7.0 105.4 0.3 11.3 38.9 3.4 2 1 1 3 3 3 0 Nucleoporin FG repeat region DUF1748 PF08520.5 ETS60830.1 - 6.1e-28 96.2 0.0 6.8e-28 96.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) LCAT PF02450.10 ETS60831.1 - 1.9e-06 27.1 0.0 2.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 ETS60831.1 - 2.3e-06 27.6 0.3 7.6e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS60831.1 - 0.0029 17.2 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Pex14_N PF04695.8 ETS60832.1 - 1e-31 109.7 0.7 2.9e-30 105.0 0.0 3.0 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 ETS60832.1 - 6.4e-06 25.8 4.1 1.2e-05 24.9 2.8 1.4 1 0 0 1 1 1 1 IncA protein HemX PF04375.9 ETS60832.1 - 0.00023 19.9 0.1 0.00039 19.1 0.1 1.3 1 0 0 1 1 1 1 HemX DUF1664 PF07889.7 ETS60832.1 - 0.0028 17.4 1.2 0.0083 15.9 0.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.6 ETS60832.1 - 0.006 15.2 3.6 0.013 14.2 2.5 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF948 PF06103.6 ETS60832.1 - 0.0065 16.3 2.7 0.42 10.5 1.3 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF4631 PF15450.1 ETS60832.1 - 0.0091 14.3 4.7 0.014 13.7 3.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) DUF3583 PF12126.3 ETS60832.1 - 0.011 14.8 1.8 0.021 13.9 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF3584 PF12128.3 ETS60832.1 - 0.018 12.4 6.6 0.025 11.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 ETS60832.1 - 0.023 14.4 6.9 0.13 11.9 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 ETS60832.1 - 0.029 14.1 0.9 0.051 13.3 0.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 ETS60832.1 - 0.058 12.8 0.3 0.19 11.1 0.2 1.9 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Reo_sigmaC PF04582.7 ETS60832.1 - 0.069 12.3 2.0 0.14 11.2 1.4 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 ETS60832.1 - 0.084 11.9 7.0 0.13 11.2 4.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2968 PF11180.3 ETS60832.1 - 0.091 12.1 6.7 0.25 10.7 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Myosin_tail_1 PF01576.14 ETS60832.1 - 0.11 10.1 11.3 0.27 8.9 2.5 1.8 1 1 1 2 2 2 0 Myosin tail Syntaxin PF00804.20 ETS60832.1 - 0.12 12.5 6.2 1.7 8.8 4.3 2.4 1 1 0 1 1 1 0 Syntaxin AAA_13 PF13166.1 ETS60832.1 - 0.12 10.8 1.9 0.17 10.3 1.3 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 ETS60832.1 - 0.12 12.0 9.5 0.32 10.7 2.6 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 ETS60832.1 - 0.14 10.2 4.7 0.071 11.2 0.8 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Enkurin PF13864.1 ETS60832.1 - 0.15 12.3 4.0 0.092 12.9 0.7 2.1 1 1 1 2 2 2 0 Calmodulin-binding Laminin_II PF06009.7 ETS60832.1 - 0.16 11.7 5.3 0.48 10.1 3.7 1.8 1 1 0 1 1 1 0 Laminin Domain II Atg14 PF10186.4 ETS60832.1 - 0.17 10.8 4.1 0.25 10.2 2.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2317 PF10079.4 ETS60832.1 - 0.18 10.3 3.8 0.26 9.8 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Mod_r PF07200.8 ETS60832.1 - 0.21 11.4 6.1 0.29 11.0 3.2 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spectrin PF00435.16 ETS60832.1 - 0.25 11.6 4.5 0.18 12.1 1.0 2.1 2 0 0 2 2 2 0 Spectrin repeat Sec20 PF03908.8 ETS60832.1 - 0.25 11.0 2.1 5.3 6.8 0.2 2.3 2 0 0 2 2 2 0 Sec20 APG17 PF04108.7 ETS60832.1 - 0.26 10.0 4.3 0.56 8.9 2.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg17 BLOC1_2 PF10046.4 ETS60832.1 - 0.26 11.4 6.3 0.63 10.2 1.7 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 ETS60832.1 - 0.29 11.2 2.6 0.71 9.9 1.6 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HisKA_3 PF07730.8 ETS60832.1 - 0.3 11.4 1.4 1.2 9.4 0.8 2.2 1 1 0 1 1 1 0 Histidine kinase NPV_P10 PF05531.7 ETS60832.1 - 0.43 10.8 6.0 1.9e+02 2.3 4.2 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 ETS60832.1 - 0.48 9.9 8.2 1.9 7.9 2.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG2 PF06148.6 ETS60832.1 - 0.62 9.9 7.7 0.86 9.4 1.5 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.1 ETS60832.1 - 0.91 8.6 6.1 1 8.4 3.5 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.13 ETS60832.1 - 0.99 8.8 8.5 2.9 7.3 5.9 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cortex-I_coil PF09304.5 ETS60832.1 - 1 9.4 11.5 1.8 8.6 1.3 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF3829 PF12889.2 ETS60832.1 - 1.1 8.4 5.8 5.7 6.0 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Mnd1 PF03962.10 ETS60832.1 - 1.1 8.8 5.8 2.4 7.7 4.0 1.5 1 0 0 1 1 1 0 Mnd1 family Cluap1 PF10234.4 ETS60832.1 - 1.2 8.2 6.3 2.3 7.3 4.4 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 ADIP PF11559.3 ETS60832.1 - 4.5 7.1 8.4 0.69 9.8 2.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RNA_pol_L_2 PF13656.1 ETS60833.1 - 2e-26 91.2 0.0 2.7e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 ETS60833.1 - 2.7e-13 48.8 0.0 3.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MBOAT_2 PF13813.1 ETS60834.1 - 5.2e-14 52.0 4.6 5.2e-14 52.0 3.2 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Myb_DNA-binding PF00249.26 ETS60835.1 - 5.7e-16 58.3 0.0 4.7e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS60835.1 - 1.9e-15 56.7 0.0 1.2e-07 31.7 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF2392 PF10288.4 ETS60836.1 - 1.4e-19 70.3 0.0 3.2e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DEDD_Tnp_IS110 PF01548.12 ETS60836.1 - 0.091 12.4 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Transposase Peptidase_M22 PF00814.20 ETS60837.1 - 2.5e-76 256.6 0.0 5.2e-75 252.3 0.0 2.6 1 1 0 1 1 1 1 Glycoprotease family APG5 PF04106.7 ETS60837.1 - 7.3e-41 139.8 0.0 1.5e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Autophagy protein Apg5 TFIID_20kDa PF03847.8 ETS60837.1 - 1.2e-29 102.4 1.4 2.2e-29 101.5 1.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF4615 PF15393.1 ETS60837.1 - 0.0021 18.2 1.4 0.0021 18.2 1.0 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4615) CBF PF03914.12 ETS60839.1 - 4.1e-40 136.9 0.7 4.9e-39 133.4 0.0 2.4 2 0 0 2 2 2 1 CBF/Mak21 family Pkinase PF00069.20 ETS60840.1 - 7.8e-61 205.4 0.0 1.5e-60 204.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60840.1 - 8.6e-19 67.6 0.3 3.1e-18 65.7 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60840.1 - 0.0022 16.9 0.1 0.056 12.4 0.1 2.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS60840.1 - 0.054 12.5 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 ETS60840.1 - 4.1 6.6 16.9 6.1 6.1 11.7 1.2 1 0 0 1 1 1 0 Vta1 like Rax2 PF12768.2 ETS60841.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 ETS60841.1 - 4.6 6.6 5.7 8.3 5.8 3.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tyr_Deacylase PF02580.11 ETS60843.1 - 4e-39 133.8 0.0 1e-24 87.1 0.0 2.1 2 0 0 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase DUF4112 PF13430.1 ETS60845.1 - 2.1e-27 95.1 0.0 2.8e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) WD40 PF00400.27 ETS60846.1 - 1.2e-12 47.1 1.4 3e-06 26.9 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Syntaxin_2 PF14523.1 ETS60847.1 - 4.9e-20 71.4 3.5 1.3e-19 70.1 0.9 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 ETS60847.1 - 2.5e-16 59.0 1.5 2.5e-16 59.0 1.0 2.7 3 0 0 3 3 3 1 SNARE domain DUF2280 PF10045.4 ETS60847.1 - 0.073 12.9 1.2 0.097 12.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Syntaxin PF00804.20 ETS60847.1 - 0.086 13.0 16.4 3.9 7.6 10.8 3.0 1 1 1 2 2 2 0 Syntaxin Ribosomal_S4 PF00163.14 ETS60848.1 - 2.6e-12 46.9 0.6 4.5e-12 46.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 ETS60848.1 - 2.4e-11 42.8 0.0 4.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain AAA_25 PF13481.1 ETS60850.1 - 0.0036 16.7 0.1 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS60850.1 - 0.036 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS60850.1 - 0.098 11.7 0.0 0.2 10.7 0.0 1.5 1 1 0 1 1 1 0 KaiC RNA12 PF10443.4 ETS60850.1 - 0.3 9.5 0.0 0.48 8.8 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein Noc2 PF03715.8 ETS60851.1 - 7.8e-104 346.7 0.7 1.2e-103 346.1 0.5 1.3 1 0 0 1 1 1 1 Noc2p family Daxx PF03344.10 ETS60851.1 - 6.2 5.1 48.7 0.2 10.1 16.3 2.3 2 0 0 2 2 2 0 Daxx Family GTP_EFTU PF00009.22 ETS60852.1 - 5.9e-34 117.1 4.1 3.9e-33 114.4 1.5 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 ETS60852.1 - 1.5e-23 82.7 1.2 3.1e-23 81.7 0.8 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 ETS60852.1 - 4.5e-06 26.6 0.1 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 ETS60852.1 - 2.4e-05 24.3 0.2 0.017 15.2 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 FeoB_N PF02421.13 ETS60852.1 - 0.00014 21.1 0.2 0.00058 19.1 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 ETS60852.1 - 0.015 14.4 1.1 0.025 13.7 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MobB PF03205.9 ETS60852.1 - 0.028 14.1 0.4 0.092 12.4 0.3 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IF2_N PF04760.10 ETS60852.1 - 0.042 13.5 0.3 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.4 ETS60852.1 - 0.043 13.3 0.6 3.2 7.2 0.0 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fez1 PF06818.10 ETS60853.1 - 0.12 12.3 38.2 0.089 12.8 6.6 3.6 2 1 0 3 3 3 0 Fez1 Spc7 PF08317.6 ETS60853.1 - 0.75 8.3 10.5 0.26 9.9 1.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 ETS60853.1 - 0.84 9.0 12.8 2.1 7.7 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) DUF3347 PF11827.3 ETS60853.1 - 1.1 9.2 7.8 2.3 8.1 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) RRM_1 PF00076.17 ETS60854.1 - 1.8e-73 242.1 3.7 8.8e-19 66.9 0.0 6.1 7 0 0 7 7 7 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60854.1 - 7.4e-69 227.6 0.5 1.5e-18 66.4 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60854.1 - 5.3e-38 128.6 3.2 1.8e-06 27.7 0.0 6.3 7 0 0 7 7 7 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 ETS60854.1 - 0.00043 20.2 0.0 0.93 9.5 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif 2 Limkain-b1 PF11608.3 ETS60854.1 - 0.023 14.4 1.7 0.23 11.2 0.0 3.6 5 0 0 5 5 5 0 Limkain b1 HTH_CodY PF08222.6 ETS60854.1 - 0.15 11.4 0.1 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain DUF89 PF01937.14 ETS60855.1 - 2.9e-109 365.1 0.0 3.3e-109 364.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Got1 PF04178.7 ETS60856.1 - 3.4e-29 101.3 12.2 4.6e-29 100.9 8.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family PIG-F PF06699.6 ETS60856.1 - 0.037 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F DUF4396 PF14342.1 ETS60856.1 - 1.1 9.4 5.9 1.9 8.5 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4396) ABC2_membrane_3 PF12698.2 ETS60856.1 - 7.7 5.4 12.7 12 4.8 8.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Cpn60_TCP1 PF00118.19 ETS60857.1 - 4e-150 500.6 2.2 4.6e-150 500.4 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mito_carr PF00153.22 ETS60858.1 - 5.7e-75 247.1 4.9 7.1e-25 86.5 0.0 4.5 4 0 0 4 4 4 4 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 ETS60859.1 - 1.5e-36 124.1 3.7 1.9e-36 123.8 2.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Ribosomal_S4 PF00163.14 ETS60861.1 - 7.5e-28 96.7 0.8 1.3e-27 96.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 ETS60861.1 - 1.2e-11 43.8 0.9 1.2e-11 43.8 0.6 3.1 4 0 0 4 4 4 1 S4 domain DNA_repr_REX1B PF14966.1 ETS60862.1 - 4.3e-08 33.4 2.9 0.0057 17.0 0.6 2.9 3 0 0 3 3 3 2 DNA repair REX1-B LEH PF07858.7 ETS60862.1 - 0.025 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain COMP PF11598.3 ETS60862.1 - 6.7 6.8 6.5 1.3 9.0 1.4 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein LSM PF01423.17 ETS60863.1 - 2.6e-17 62.1 0.2 3.2e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Glyco_hydro_35 PF01301.14 ETS60864.1 - 5.9e-72 242.7 0.0 8.6e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 ETS60864.1 - 5.6e-37 126.4 3.4 2.2e-19 69.7 0.1 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 ETS60864.1 - 2.2e-10 40.2 0.0 6.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 Cellulase PF00150.13 ETS60864.1 - 7.2e-06 25.3 0.0 0.00017 20.9 0.0 2.5 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom3 PF13363.1 ETS60864.1 - 0.084 12.2 0.0 0.28 10.6 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Pkinase PF00069.20 ETS60865.1 - 6.7e-73 245.0 0.0 8.2e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60865.1 - 6.5e-32 110.6 0.0 8.4e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETS60865.1 - 0.00014 20.9 0.0 0.0005 19.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS60865.1 - 0.00048 19.9 0.0 0.00098 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS60865.1 - 0.002 17.1 0.0 0.015 14.2 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 ETS60865.1 - 0.017 14.4 0.0 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family muHD PF10291.4 ETS60867.1 - 7.2e-53 179.3 0.0 1e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 ETS60867.1 - 1.7e-10 40.9 0.0 1.7e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2335 PF10097.4 ETS60867.1 - 0.13 11.9 0.8 7.1 6.3 0.0 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) eIF2_C PF09173.6 ETS60868.1 - 4.2e-38 129.2 0.1 1.1e-37 127.8 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 ETS60868.1 - 3.1e-37 127.8 0.0 5.4e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 ETS60868.1 - 2.6e-13 49.8 2.1 3.7e-13 49.3 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS60868.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETS60868.1 - 0.07 12.9 0.3 0.21 11.3 0.2 2.1 1 1 0 1 1 1 0 Dynamin family ATP_sub_h PF10775.4 ETS60869.1 - 1.1e-23 82.6 1.9 1.7e-23 82.0 1.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 ETS60869.1 - 0.018 14.9 0.1 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 IATP PF04568.7 ETS60870.1 - 6.2e-18 64.6 2.0 7.1e-18 64.4 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Rabaptin PF03528.10 ETS60870.1 - 4.6e-05 23.2 1.9 4.6e-05 23.2 1.3 1.1 1 0 0 1 1 1 1 Rabaptin UPF0449 PF15136.1 ETS60870.1 - 0.0031 17.6 1.4 0.0037 17.4 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 DUF1366 PF07104.6 ETS60870.1 - 0.0039 16.7 5.4 0.0057 16.2 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1366) DUF2968 PF11180.3 ETS60870.1 - 0.0091 15.3 4.0 0.009 15.4 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF16 PF01519.11 ETS60870.1 - 0.0099 16.0 1.7 0.0099 16.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF16 IncA PF04156.9 ETS60870.1 - 0.014 15.0 1.7 0.012 15.1 1.2 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 ETS60870.1 - 0.017 14.0 2.4 0.015 14.2 1.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HemX PF04375.9 ETS60870.1 - 0.02 13.4 3.7 0.022 13.3 2.5 1.0 1 0 0 1 1 1 0 HemX MOFRL PF05161.8 ETS60870.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.2 1 1 0 1 1 1 0 MOFRL family AAA_23 PF13476.1 ETS60870.1 - 0.033 14.4 2.3 0.03 14.6 1.6 1.1 1 0 0 1 1 1 0 AAA domain OSTbeta PF15048.1 ETS60870.1 - 0.055 13.5 1.2 0.052 13.6 0.8 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2730 PF10805.3 ETS60870.1 - 0.093 12.4 1.8 0.14 11.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4140 PF13600.1 ETS60870.1 - 0.15 12.5 5.2 0.21 12.0 3.6 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NinG PF05766.7 ETS60870.1 - 0.39 10.4 4.8 0.47 10.1 3.4 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Vps5 PF09325.5 ETS60870.1 - 0.88 8.7 9.3 1.1 8.4 6.4 1.1 1 0 0 1 1 1 0 Vps5 C terminal like PspB PF06667.7 ETS60870.1 - 3.4 7.6 5.3 4.8 7.1 3.7 1.2 1 0 0 1 1 1 0 Phage shock protein B Bap31 PF05529.7 ETS60870.1 - 5.4 6.4 7.9 6.4 6.1 5.4 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 ETS60870.1 - 9.8 5.0 7.9 12 4.7 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_12 PF13087.1 ETS60871.1 - 1.4e-54 184.5 0.0 3.7e-54 183.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 ETS60871.1 - 1.3e-47 162.3 0.7 2e-47 161.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain PS_Dcarbxylase PF02666.10 ETS60871.1 - 2.9e-43 147.5 0.0 4.9e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AAA_30 PF13604.1 ETS60871.1 - 3.7e-11 42.9 1.5 1.2e-08 34.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 ETS60871.1 - 8.6e-11 41.4 2.9 1.2e-10 40.9 0.5 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 ETS60871.1 - 0.0012 18.3 0.0 13 5.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 ETS60871.1 - 0.0029 17.5 0.3 2.3 8.1 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain UvrD-helicase PF00580.16 ETS60871.1 - 0.0049 16.2 0.2 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 ETS60871.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein HMG_box PF00505.14 ETS60872.1 - 1.5e-23 82.8 1.2 3e-23 81.8 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS60872.1 - 1.2e-18 67.2 1.7 2.6e-18 66.1 1.2 1.6 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 ETS60872.1 - 0.024 14.3 0.0 0.055 13.1 0.0 1.6 2 0 0 2 2 2 0 CHDNT (NUC034) domain Mito_carr PF00153.22 ETS60873.1 - 8.2e-66 217.7 4.6 3.6e-23 81.0 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP9-21 PF05486.7 ETS60874.1 - 3.2e-19 68.4 0.5 4.9e-19 67.8 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF1180 PF06679.7 ETS60874.1 - 5.3 6.9 6.3 10 5.9 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RINGv PF12906.2 ETS60875.1 - 3.4e-07 30.1 6.3 6.4e-07 29.3 4.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 ETS60875.1 - 0.0036 17.3 3.7 0.006 16.6 2.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 ETS60875.1 - 0.015 15.1 8.7 0.037 13.8 6.0 1.7 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 ETS60875.1 - 0.037 13.6 1.1 0.073 12.6 0.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tmpp129 PF10272.4 ETS60875.1 - 0.4 9.3 3.5 0.6 8.7 2.4 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C3HC4 PF00097.20 ETS60875.1 - 0.76 9.4 3.9 1.3 8.7 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS60875.1 - 0.94 9.1 6.8 3.1 7.5 4.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 2OG-FeII_Oxy_2 PF13532.1 ETS60876.1 - 6.7e-14 52.1 0.0 1.8e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETS60876.1 - 6.9e-05 23.0 0.1 0.087 13.1 0.0 2.7 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Antimicrobial14 PF08109.6 ETS60876.1 - 0.19 11.5 0.2 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Lactocin 705 family RVT_1 PF00078.22 ETS60878.1 - 1.5e-12 47.3 0.0 1.6e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vps35 PF03635.12 ETS60879.1 - 0 1145.6 0.0 0 1145.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MT-A70 PF05063.9 ETS60880.1 - 4.1e-45 153.4 0.0 5.3e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 MT-A70 WD40 PF00400.27 ETS60881.1 - 2.2e-24 84.3 8.2 2.3e-06 27.2 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 ETS60881.1 - 8.1e-05 22.4 0.5 0.051 13.2 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 ETS60881.1 - 0.0011 18.6 0.5 0.43 10.3 0.1 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 ETS60881.1 - 0.0035 16.8 0.0 0.79 9.2 0.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain tRNA_int_endo PF01974.12 ETS60882.1 - 3.2e-21 74.9 0.0 6.4e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 ETS60882.1 - 7e-06 25.5 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Complex1_LYR_1 PF13232.1 ETS60883.1 - 1.1e-16 60.8 0.3 1.5e-16 60.3 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 ETS60883.1 - 3.9e-09 36.1 7.8 2.2e-08 33.7 4.1 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 ETS60883.1 - 0.065 13.7 0.0 0.089 13.2 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like RRM_1 PF00076.17 ETS60884.1 - 3.2e-17 61.8 0.0 5.3e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60884.1 - 1.1e-12 47.7 0.0 1.9e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60884.1 - 1.7e-07 30.9 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 ETS60884.1 - 5.7 5.3 9.0 9.2 4.6 6.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Bromo_TP PF07524.8 ETS60885.1 - 1e-11 44.3 0.2 3.2e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated Oxidored_molyb PF00174.14 ETS60886.1 - 4.4e-42 143.3 0.0 6.4e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 ETS60886.1 - 1.5e-14 53.7 1.9 4.5e-13 48.9 1.3 2.3 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DUF1962 PF09227.5 ETS60886.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) SE PF08491.5 ETS60887.1 - 2.5e-99 331.5 0.0 4.6e-99 330.7 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 ETS60887.1 - 3.8e-11 42.5 0.2 4.4e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS60887.1 - 9.3e-11 41.3 0.0 2.8e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS60887.1 - 9.3e-05 22.3 0.3 0.00023 21.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS60887.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS60887.1 - 0.00083 18.5 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 ETS60887.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 ETS60887.1 - 0.0021 16.9 0.3 0.025 13.4 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 ETS60887.1 - 0.0031 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 ETS60887.1 - 0.01 14.7 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS60887.1 - 0.018 15.4 0.0 0.058 13.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS60887.1 - 0.029 14.0 0.1 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 ETS60887.1 - 0.057 12.3 0.1 0.72 8.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 ETS60887.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 ETS60887.1 - 0.15 10.4 0.0 0.42 9.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 ETS60887.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ubiq_cyt_C_chap PF03981.7 ETS60888.1 - 0.0013 18.6 0.0 0.61 9.9 0.1 2.5 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Bap31 PF05529.7 ETS60889.1 - 5.6e-57 192.3 4.4 7.9e-57 191.8 3.1 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4446 PF14584.1 ETS60889.1 - 0.0052 16.6 1.8 0.0079 16.0 0.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF4446) DUF4407 PF14362.1 ETS60889.1 - 0.14 11.0 1.7 0.18 10.7 1.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short PF00106.20 ETS60890.1 - 8.3e-22 77.8 0.3 1.1e-21 77.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS60890.1 - 2.7e-13 50.2 0.0 3.6e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS60890.1 - 3.7e-05 23.4 0.2 6.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF562 PF04763.7 ETS60890.1 - 0.0059 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF562) DUF1776 PF08643.5 ETS60890.1 - 0.041 13.0 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 ETS60890.1 - 0.11 12.1 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ferric_reduct PF01794.14 ETS60891.1 - 2.3e-20 72.9 5.2 2.3e-20 72.9 3.6 3.1 2 2 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS60891.1 - 4.2e-15 55.9 0.0 2.2e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS60891.1 - 4.6e-15 55.3 0.0 1.1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 ETS60891.1 - 3.1e-05 24.5 0.0 0.29 11.7 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF202 PF02656.10 ETS60891.1 - 9.1 6.5 9.7 8.3 6.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF202) TBP PF00352.16 ETS60892.1 - 3.3e-67 221.8 0.2 6.9e-33 111.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 ETS60892.1 - 9.1e-05 22.4 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) NUDIX_2 PF13869.1 ETS60893.1 - 7.6e-80 266.6 0.0 8.6e-80 266.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF883 PF05957.8 ETS60894.1 - 0.036 14.4 3.4 0.097 13.0 2.4 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HAUS-augmin3 PF14932.1 ETS60894.1 - 0.061 12.4 0.2 0.099 11.8 0.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.9 ETS60894.1 - 0.14 12.0 2.5 0.28 11.0 1.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HSCB_C PF07743.8 ETS60894.1 - 2.9 8.4 4.8 21 5.6 0.9 2.6 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain OPA3 PF07047.7 ETS60895.1 - 1.2e-31 109.1 0.6 2.7e-31 108.1 0.4 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Glyco_transf_20 PF00982.16 ETS60896.1 - 6.1e-153 509.6 0.0 8.4e-153 509.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 ETS60896.1 - 1.3e-18 66.7 0.0 2.4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Pkinase PF00069.20 ETS60898.1 - 9.6e-45 152.7 0.0 3.6e-44 150.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60898.1 - 1.5e-24 86.5 0.0 2.7e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS60898.1 - 0.029 13.3 0.0 0.056 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like OTU PF02338.14 ETS60900.1 - 1.2e-14 54.9 0.0 3.3e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease RPA_interact_C PF14768.1 ETS60901.1 - 0.035 14.4 0.2 0.054 13.8 0.2 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal ox_reductase_C PF08635.5 ETS60902.1 - 4.8e-77 256.2 0.1 7e-77 255.6 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 ETS60902.1 - 4.4e-26 91.7 0.0 7.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS60902.1 - 0.14 11.9 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain Cofilin_ADF PF00241.15 ETS60903.1 - 3e-11 43.3 0.0 3.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CTNNBL PF08216.6 ETS60905.1 - 7.4e-25 86.6 0.0 2.4e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 ETS60905.1 - 0.0091 16.2 2.1 0.0091 16.2 1.4 4.4 3 3 0 3 3 3 1 HEAT repeats Drf_GBD PF06371.8 ETS60905.1 - 0.038 13.3 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain FliT PF05400.8 ETS60905.1 - 0.74 10.2 9.0 1.9 8.9 0.4 3.5 3 0 0 3 3 3 0 Flagellar protein FliT RRM_1 PF00076.17 ETS60906.1 - 4.6e-16 58.1 0.0 8.2e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60906.1 - 1.3e-09 37.8 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60906.1 - 0.00022 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N_2 PF13602.1 ETS60907.1 - 4.6e-09 37.2 0.0 1.7e-08 35.3 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS60907.1 - 2.1e-05 24.2 0.2 5.2e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS60907.1 - 0.055 13.0 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GTP_EFTU PF00009.22 ETS60910.1 - 1.4e-50 171.3 0.0 3.1e-50 170.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 ETS60910.1 - 8.6e-14 51.1 0.0 2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 ETS60910.1 - 7.5e-09 35.3 0.0 2.2e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 ETS60910.1 - 2.2e-05 24.3 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 ETS60910.1 - 2.7e-05 23.6 0.0 0.00066 19.2 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 ETS60910.1 - 0.0027 17.7 0.0 0.01 15.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 ETS60910.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family WD40 PF00400.27 ETS60911.1 - 1.6e-52 173.6 18.9 7.3e-10 38.3 0.3 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETS60911.1 - 9.4e-06 24.1 0.0 1.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 ETS60911.1 - 0.0049 17.1 4.4 10 6.5 0.3 4.6 4 0 0 4 4 4 1 PQQ-like domain Nup160 PF11715.3 ETS60911.1 - 0.012 13.7 1.9 2.1 6.3 0.1 3.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF3312 PF11768.3 ETS60911.1 - 0.034 12.3 0.0 0.15 10.2 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) RE_HaeII PF09554.5 ETS60911.1 - 0.22 10.4 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 HaeII restriction endonuclease Glyoxalase_2 PF12681.2 ETS60913.1 - 8.1e-06 26.3 0.0 0.00044 20.8 0.0 2.6 1 1 0 1 1 1 1 Glyoxalase-like domain Cauli_VI PF01693.11 ETS60913.1 - 2.2e-05 24.3 0.1 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyoxalase PF00903.20 ETS60913.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sec16 PF12932.2 ETS60913.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region TRAP-gamma PF07074.7 ETS60914.1 - 0.086 12.3 0.6 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) BAP PF06639.6 ETS60914.1 - 0.097 12.3 1.5 0.15 11.8 0.2 1.8 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Mito_carr PF00153.22 ETS60915.1 - 2.7e-54 180.8 7.5 1.3e-17 63.2 0.3 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein NOG1 PF06858.9 ETS60916.1 - 3.4e-28 97.2 0.1 6.3e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 ETS60916.1 - 1.4e-27 95.1 3.4 3.5e-27 93.8 2.4 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 ETS60916.1 - 9.7e-18 64.2 0.0 2.4e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS60916.1 - 4.1e-08 32.6 0.0 8.4e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 ETS60916.1 - 0.00043 20.7 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 ETS60916.1 - 0.0084 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 ETS60916.1 - 0.011 14.9 0.0 0.1 11.7 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 ETS60916.1 - 0.058 13.2 1.1 2.3 7.9 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Aldedh PF00171.17 ETS60918.1 - 1.3e-107 360.0 0.0 1.5e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LSM PF01423.17 ETS60919.1 - 5.6e-19 67.4 0.8 7.7e-19 67.0 0.6 1.2 1 0 0 1 1 1 1 LSM domain MRJP PF03022.11 ETS60919.1 - 0.015 14.5 0.0 0.018 14.2 0.0 1.0 1 0 0 1 1 1 0 Major royal jelly protein DUF1541 PF07563.6 ETS60919.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) DUF765 PF05570.6 ETS60919.1 - 4.1 7.4 7.7 0.36 10.8 1.9 1.8 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) Ribosomal_L5_C PF00673.16 ETS60920.1 - 4.9e-06 26.1 0.0 1.6e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 ETS60920.1 - 0.0015 18.2 0.6 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 Cullin_binding PF03556.10 ETS60921.1 - 2.2e-33 114.8 1.3 4.1e-33 113.9 0.9 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 ETS60921.1 - 2.5e-07 30.0 0.1 5.5e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain TipAS PF07739.8 ETS60921.1 - 0.39 11.0 4.3 0.9 9.8 1.5 2.6 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Iso_dh PF00180.15 ETS60922.1 - 9.6e-116 386.5 0.0 1.1e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-RING_2 PF13639.1 ETS60923.1 - 8.8e-14 51.0 4.0 1.4e-13 50.3 2.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 ETS60923.1 - 4.2e-09 36.0 0.1 2.9e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 ETS60923.1 - 3.6e-07 30.0 4.2 5.9e-07 29.3 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS60923.1 - 3.1e-06 26.8 1.8 4.7e-06 26.2 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETS60923.1 - 3.4e-06 27.0 0.7 6e-06 26.2 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETS60923.1 - 1.9e-05 24.1 2.2 3e-05 23.5 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS60923.1 - 0.00034 20.1 1.3 0.00054 19.5 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS60923.1 - 0.039 13.7 1.0 0.085 12.6 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 ETS60923.1 - 0.087 12.8 3.1 0.47 10.4 2.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 ETS60923.1 - 0.94 9.2 5.8 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger ATP_bind_1 PF03029.12 ETS60924.1 - 2.7e-82 275.9 0.0 3.1e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 ETS60924.1 - 2.7e-07 31.4 0.1 5.6e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 ETS60924.1 - 4.5e-06 26.1 0.0 1.1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 ETS60924.1 - 0.00017 21.5 0.2 0.0042 17.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS60924.1 - 0.00054 19.4 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 ETS60924.1 - 0.00071 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein T2SE PF00437.15 ETS60924.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETS60924.1 - 0.0012 18.9 0.0 0.0043 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS60924.1 - 0.0012 19.1 0.0 0.0031 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ETS60924.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 ETS60924.1 - 0.0017 17.8 0.0 0.4 10.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 ETS60924.1 - 0.002 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 ETS60924.1 - 0.003 17.2 0.0 0.0076 15.9 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETS60924.1 - 0.003 17.7 0.0 0.041 14.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 ETS60924.1 - 0.0038 16.8 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS60924.1 - 0.0045 16.8 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS60924.1 - 0.0054 16.6 0.0 0.026 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS60924.1 - 0.0072 15.7 1.2 0.055 12.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 ETS60924.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain MMR_HSR1 PF01926.18 ETS60924.1 - 0.0082 16.0 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 ETS60924.1 - 0.015 15.5 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 ETS60924.1 - 0.037 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS60924.1 - 0.039 13.0 0.0 0.058 12.4 0.0 1.5 1 1 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 ETS60924.1 - 0.041 13.3 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 ETS60924.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NTPase CobU PF02283.11 ETS60924.1 - 0.075 12.4 0.1 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NACHT PF05729.7 ETS60924.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 ETS60924.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Gtr1_RagA PF04670.7 ETS60924.1 - 0.1 11.7 0.1 4 6.5 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SRP54 PF00448.17 ETS60924.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MipZ PF09140.6 ETS60924.1 - 0.15 11.1 0.0 1.5 7.8 0.0 2.2 1 1 0 1 1 1 0 ATPase MipZ Zeta_toxin PF06414.7 ETS60924.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin 2-Hacid_dh_C PF02826.14 ETS60928.1 - 1.1e-52 177.7 0.0 4.3e-52 175.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS60928.1 - 3.5e-32 110.6 0.0 5.7e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS60928.1 - 0.00066 19.5 0.1 0.0019 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 ETS60928.1 - 0.0016 18.2 0.5 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 ETS60928.1 - 8.8 5.9 6.9 5.1 6.7 0.2 2.9 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_C1_2 PF03051.10 ETS60929.1 - 4.1e-143 477.0 0.0 1.2e-142 475.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 ETS60929.1 - 0.00021 21.2 0.9 0.18 11.6 0.0 2.7 2 1 0 2 2 2 2 Papain family cysteine protease Glycos_transf_2 PF00535.21 ETS60930.1 - 3e-21 75.8 0.0 1.3e-20 73.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ETS60930.1 - 2.7e-11 43.7 0.4 5.4e-08 32.9 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 DUF2493 PF10686.4 ETS60930.1 - 0.0091 15.5 0.1 0.023 14.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2493) Glyco_tranf_2_4 PF13704.1 ETS60930.1 - 0.09 13.1 0.0 0.27 11.5 0.0 1.8 1 1 1 2 2 2 0 Glycosyl transferase family 2 GNAT_acetyltr_2 PF13718.1 ETS60931.1 - 2.8e-75 251.9 0.0 4.8e-75 251.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 ETS60931.1 - 5.7e-65 218.2 0.0 1e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 ETS60931.1 - 1e-32 111.6 0.0 2.6e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 ETS60931.1 - 4.6e-28 97.2 0.8 1.4e-27 95.7 0.2 2.2 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 ETS60931.1 - 0.0011 18.9 0.0 0.0044 17.0 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS60931.1 - 0.0015 18.6 0.0 0.028 14.5 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RXT2_N PF08595.6 ETS60931.1 - 5.5 6.7 8.9 9.9 5.9 5.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 ETS60931.1 - 6.2 6.3 11.2 13 5.2 7.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin Peptidase_C97 PF05903.9 ETS60932.1 - 1.2e-20 73.7 0.0 1.5e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain LRAT PF04970.8 ETS60932.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase zf-PARP PF00645.13 ETS60933.1 - 5.1e-21 74.6 0.0 7.3e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.14 ETS60933.1 - 1.3e-19 67.3 109.5 0.063 12.9 0.6 11.5 11 0 0 11 11 11 11 AT hook motif Mito_carr PF00153.22 ETS60934.1 - 8.1e-60 198.5 7.4 9.9e-22 76.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 ETS60934.1 - 0.018 15.1 0.1 0.069 13.3 0.1 2.0 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 ETS60934.1 - 0.019 14.2 2.4 0.084 12.2 0.1 3.1 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 ETS60934.1 - 0.052 13.4 0.1 0.25 11.3 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.20 ETS60935.1 - 4.9e-12 45.5 0.0 9e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Seadorna_VP7 PF07387.6 ETS60935.1 - 3.9e-05 22.6 0.0 5.6e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 ETS60935.1 - 0.00011 22.0 3.0 0.00068 19.4 0.1 3.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS60935.1 - 0.0029 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS60935.1 - 0.045 12.8 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETS60935.1 - 0.19 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 ETS60935.1 - 0.5 9.4 0.4 3.2 6.8 0.3 2.1 1 1 0 1 1 1 0 Ecdysteroid kinase SRF-TF PF00319.13 ETS60936.1 - 3.6e-21 74.1 0.1 5.7e-21 73.4 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Nucleoplasmin PF03066.10 ETS60936.1 - 0.24 10.9 5.4 0.14 11.6 1.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 ETS60936.1 - 0.75 7.7 20.7 0.056 11.4 2.5 2.3 1 1 1 2 2 2 0 CDC45-like protein Sporozoite_P67 PF05642.6 ETS60936.1 - 0.87 7.3 26.4 1.2 6.9 2.7 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Prothymosin PF03247.9 ETS60936.1 - 2.8 8.1 19.9 0.26 11.4 5.8 3.0 3 0 0 3 3 3 0 Prothymosin/parathymosin family ABC1 PF03109.11 ETS60937.1 - 3e-25 88.4 0.0 6.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Paf67 PF10255.4 ETS60939.1 - 3.2e-161 536.7 0.2 4.5e-161 536.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Med8 PF10232.4 ETS60939.1 - 0.2 11.1 2.5 1 8.8 1.8 2.1 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Exo_endo_phos PF03372.18 ETS60940.1 - 1.7e-11 44.5 0.0 7.3e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family U79_P34 PF03064.11 ETS60940.1 - 0.18 11.2 2.5 0.39 10.2 1.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FYVE PF01363.16 ETS60941.1 - 8.5e-21 73.6 2.4 1.5e-20 72.8 1.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger TerY-C PF15616.1 ETS60941.1 - 0.032 14.1 0.2 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-DHHC PF01529.15 ETS60941.1 - 0.2 11.0 1.1 0.91 8.8 0.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase ETF_QO PF05187.8 ETS60943.1 - 2.6e-43 146.4 0.0 4.2e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 ETS60943.1 - 3.1e-07 29.6 0.5 1.2e-05 24.4 0.6 2.2 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 ETS60943.1 - 1.9e-06 27.0 1.2 0.00047 19.1 0.7 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS60943.1 - 2e-06 27.7 0.0 7.1e-06 25.9 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS60943.1 - 2.1e-05 23.1 0.5 3.2e-05 22.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 ETS60943.1 - 7.1e-05 22.7 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS60943.1 - 0.00013 21.1 0.3 0.00025 20.2 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 ETS60943.1 - 0.00019 20.4 0.1 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 ETS60943.1 - 0.0012 18.5 0.8 0.0029 17.3 0.3 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS60943.1 - 0.0026 16.8 0.3 0.0041 16.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETS60943.1 - 0.0028 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS60943.1 - 0.0031 17.5 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS60943.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 ETS60943.1 - 0.025 13.2 0.7 0.045 12.3 0.5 1.4 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 ETS60943.1 - 0.026 13.3 0.3 0.04 12.7 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_7 PF12838.2 ETS60943.1 - 0.07 13.5 1.8 0.15 12.4 1.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.1 ETS60943.1 - 0.09 12.6 0.7 0.16 11.8 0.5 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 ETS60943.1 - 4.1 7.4 6.0 0.24 11.3 0.5 1.6 2 0 0 2 2 1 0 4Fe-4S binding domain DUF3321 PF11968.3 ETS60944.1 - 1.9e-72 243.4 0.0 2.7e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 ETS60944.1 - 5.2e-05 23.0 0.0 0.00025 20.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MAS20 PF02064.10 ETS60945.1 - 5.5e-19 68.2 0.8 4.1e-18 65.4 0.6 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor PPP4R2 PF09184.6 ETS60945.1 - 5.7 6.4 13.0 1.2 8.5 2.6 2.4 2 0 0 2 2 2 0 PPP4R2 UQ_con PF00179.21 ETS60946.1 - 2.2e-50 169.7 0.0 2.6e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS60946.1 - 4.9e-07 29.5 0.0 1.4e-06 28.0 0.0 1.6 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 ETS60946.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 RWD domain DnaJ PF00226.26 ETS60947.1 - 3.3e-24 84.3 0.2 7.4e-24 83.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 ETS60947.1 - 7.4e-23 80.8 0.3 1.2e-22 80.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DUF2404 PF10296.4 ETS60948.1 - 0.0024 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) CAP PF00188.21 ETS60950.1 - 8e-27 94.1 6.5 1.7e-26 93.1 4.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Collagen PF01391.13 ETS60950.1 - 0.0074 15.8 3.5 0.014 14.9 0.4 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) zf-U1 PF06220.7 ETS60950.1 - 0.093 12.3 2.7 0.25 10.9 1.9 1.7 1 0 0 1 1 1 0 U1 zinc finger Hid1 PF12722.2 ETS60950.1 - 2.4 5.7 5.0 3.2 5.3 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MOZ_SAS PF01853.13 ETS60951.1 - 2.1e-58 196.6 0.1 1.8e-57 193.6 0.0 2.3 3 0 0 3 3 3 1 MOZ/SAS family Methyltransf_23 PF13489.1 ETS60951.1 - 7e-13 48.6 0.0 1.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS60951.1 - 2.1e-12 47.6 0.0 1.2e-11 45.1 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS60951.1 - 4e-11 43.2 0.0 1.7e-10 41.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS60951.1 - 1.4e-10 41.5 0.0 7.3e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Tudor-knot PF11717.3 ETS60951.1 - 9.3e-09 34.8 0.0 2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF938 PF06080.7 ETS60951.1 - 4.1e-06 26.4 0.0 8.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.1 ETS60951.1 - 4.7e-06 26.9 0.0 1.7e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS60951.1 - 0.00027 20.5 0.0 0.00073 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 ETS60951.1 - 0.29 9.9 0.0 0.51 9.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 ETS60951.1 - 0.3 10.4 0.0 1.4 8.3 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase small domain TPR_12 PF13424.1 ETS60952.1 - 0.0002 21.2 1.7 0.51 10.3 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat DeoC PF01791.4 ETS60953.1 - 9.7e-44 149.4 3.7 1.2e-43 149.0 2.5 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.16 ETS60953.1 - 0.024 13.8 0.3 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein Aminotran_1_2 PF00155.16 ETS60954.1 - 1.2e-39 136.3 0.0 1.6e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3818 PF12825.2 ETS60955.1 - 3.3e-123 410.7 0.0 4.4e-123 410.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 ETS60955.1 - 4.8e-42 142.8 0.9 1.2e-41 141.5 0.6 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 ETS60955.1 - 4.6e-07 29.6 0.0 3.1e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 PX domain MRP-L20 PF12824.2 ETS60956.1 - 3.3e-33 114.9 4.4 4.1e-33 114.6 2.1 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.9 ETS60956.1 - 1.7e-05 24.8 0.0 0.00014 21.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS60956.1 - 0.00089 19.0 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS60956.1 - 0.0032 17.5 0.2 0.0062 16.6 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS60956.1 - 0.0082 15.0 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Malic_M PF03949.10 ETS60956.1 - 0.16 11.5 0.2 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Trypsin_2 PF13365.1 ETS60957.1 - 3.6e-06 26.9 0.1 1.3e-05 25.2 0.1 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Arylesterase PF01731.15 ETS60958.1 - 0.085 12.8 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 Arylesterase SBBP PF06739.6 ETS60958.1 - 0.61 9.9 2.6 0.6 9.9 0.4 2.0 2 0 0 2 2 2 0 Beta-propeller repeat DUF3292 PF11696.3 ETS60960.1 - 3e-191 636.6 0.6 2.4e-187 623.7 0.4 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) ORC5_C PF14630.1 ETS60961.1 - 2.3e-50 171.5 0.1 4.6e-49 167.3 0.1 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DNA_ligase_A_M PF01068.16 ETS60962.1 - 1.2e-08 34.5 0.0 5.6e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 ETS60962.1 - 1.3e-05 24.7 0.1 4e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 DNA ligase OB-like domain DUF1153 PF06627.6 ETS60962.1 - 0.0049 16.7 0.0 0.091 12.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1153) EF1_GNE PF00736.14 ETS60963.1 - 3.6e-28 97.0 1.7 3.6e-28 97.0 1.2 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 ETS60963.1 - 1e-13 51.1 4.0 1e-13 51.1 2.8 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.7 ETS60963.1 - 0.0082 15.8 0.4 0.012 15.3 0.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Usp PF00582.21 ETS60964.1 - 2.2e-20 73.2 0.1 3.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Toprim_4 PF13662.1 ETS60964.1 - 3.2e-05 23.8 0.1 0.00065 19.6 0.0 2.2 2 0 0 2 2 2 1 Toprim domain DUF3253 PF11625.3 ETS60964.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Phage_DsbA PF11126.3 ETS60964.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DsbA DUF218 PF02698.12 ETS60965.1 - 1e-05 25.0 0.0 0.018 14.5 0.0 2.3 1 1 0 2 2 2 2 DUF218 domain TFIIS_M PF07500.9 ETS60966.1 - 6.8e-20 71.2 0.0 9.7e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain RNA_pol_L_2 PF13656.1 ETS60967.1 - 1.4e-23 82.0 0.0 1.4e-22 78.8 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 ETS60967.1 - 3.3e-07 29.3 0.0 6.7e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SNF2_N PF00176.18 ETS60968.1 - 3.2e-83 278.9 2.2 6.5e-83 277.9 1.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS60968.1 - 9.9e-18 63.7 0.0 1.1e-16 60.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 ETS60968.1 - 2e-17 62.7 6.8 2e-17 62.7 4.7 3.6 3 0 0 3 3 3 1 HSA Bromodomain PF00439.20 ETS60968.1 - 2.1e-15 56.3 0.0 5.2e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 ETS60968.1 - 7.5e-15 54.8 2.6 7.5e-15 54.8 1.8 3.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 ETS60968.1 - 3.7e-13 48.6 1.0 3.7e-13 48.6 0.7 2.0 2 0 0 2 2 2 1 QLQ RRM_1 PF00076.17 ETS60969.1 - 1e-48 162.7 0.0 2e-20 72.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS60969.1 - 5e-38 128.9 0.0 1.7e-12 47.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS60969.1 - 6.7e-23 80.2 0.0 2.3e-08 33.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 ETS60969.1 - 0.031 14.0 0.0 0.41 10.4 0.0 2.4 3 0 0 3 3 3 0 Limkain b1 DUF2456 PF10445.4 ETS60970.1 - 7.5e-30 102.7 1.9 1.4e-29 101.8 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) Pkinase PF00069.20 ETS60971.1 - 2.1e-58 197.5 0.0 2.4e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS60971.1 - 1.4e-19 70.1 0.0 2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS60971.1 - 4.3e-07 29.9 0.0 4.5e-06 26.5 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS60971.1 - 0.022 14.3 0.2 0.022 14.3 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 ETS60971.1 - 0.026 13.6 0.1 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ded_cyto PF06920.8 ETS60974.1 - 2.7e-41 140.8 0.0 4.7e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 ETS60974.1 - 1.1e-33 116.4 0.0 3.3e-33 114.8 0.0 1.8 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins tRNA-synt_2d PF01409.15 ETS60975.1 - 2.5e-47 161.1 0.0 7.8e-26 90.7 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 ETS60975.1 - 4.4e-24 84.4 0.1 9.3e-24 83.4 0.1 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PAP_assoc PF03828.14 ETS60977.1 - 6.1e-21 74.1 0.0 1.4e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETS60977.1 - 1.8e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4551 PF15087.1 ETS60977.1 - 3.1 6.0 4.2 5.2 5.3 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DEAD PF00270.24 ETS60978.1 - 1.8e-46 157.6 0.0 1.6e-45 154.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS60978.1 - 1.4e-23 82.5 0.0 7.6e-23 80.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETS60978.1 - 0.00045 19.1 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain KTI12 PF08433.5 ETS60979.1 - 1.1e-58 198.5 0.0 1.8e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 ETS60979.1 - 2.4e-07 30.7 0.0 5.4e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain FAD_binding_2 PF00890.19 ETS60980.1 - 9.5e-127 423.2 3.2 1.2e-126 422.9 2.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 ETS60980.1 - 1.7e-48 163.6 0.7 2.6e-48 163.1 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 ETS60980.1 - 8.7e-06 24.8 0.1 0.002 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 ETS60980.1 - 1e-05 24.7 0.4 0.0028 16.8 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 ETS60980.1 - 1.2e-05 24.4 1.1 0.03 13.1 1.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETS60980.1 - 0.0017 18.3 5.9 0.023 14.5 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS60980.1 - 0.0074 15.3 0.2 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS60980.1 - 0.049 13.6 0.9 3.8 7.5 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS60980.1 - 0.12 10.7 2.7 0.5 8.7 0.5 2.7 3 0 0 3 3 3 0 HI0933-like protein Sec7 PF01369.15 ETS60981.1 - 2.8e-61 206.4 0.0 4.8e-61 205.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETS60981.1 - 2.9e-16 59.3 1.3 2e-10 40.3 0.1 2.7 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RNase_H2-Ydr279 PF09468.5 ETS60981.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AAR2 PF05282.6 ETS60982.1 - 2e-60 204.6 0.0 2.5e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein CaATP_NAI PF12515.3 ETS60982.1 - 0.099 12.1 0.7 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Epimerase PF01370.16 ETS60984.1 - 0.0035 16.8 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1188 PF06690.6 ETS60984.1 - 0.039 13.1 0.1 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Cellulase PF00150.13 ETS60985.1 - 3.7e-14 52.5 16.8 1.1e-13 51.0 11.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ATG_C PF09333.6 ETS60986.1 - 1.2e-21 76.6 0.2 3.6e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 ETS60986.1 - 7.5e-11 41.6 0.0 2.7e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 ETS60986.1 - 1.4e-05 24.7 0.4 3.1e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif bZIP_C PF12498.3 ETS60986.1 - 0.0015 19.7 0.3 0.0096 17.1 0.2 2.5 1 0 0 1 1 1 1 Basic leucine-zipper C terminal RabGAP-TBC PF00566.13 ETS60987.1 - 3.6e-26 91.9 0.0 1.8e-21 76.5 0.0 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain CDC50 PF03381.10 ETS60988.1 - 4.1e-96 321.4 0.1 5e-96 321.1 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SnoaL PF07366.7 ETS60989.1 - 7.9e-07 28.7 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 ETS60989.1 - 0.00033 21.0 0.0 0.00092 19.5 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain Peptidase_S66 PF02016.10 ETS60989.1 - 0.048 12.5 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase AMP-binding PF00501.23 ETS60990.1 - 1.8e-86 290.1 0.0 2.4e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS60990.1 - 7.6e-12 46.0 0.8 2.2e-11 44.5 0.6 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RhoGAP PF00620.22 ETS60991.1 - 3.6e-39 133.8 0.0 7.2e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 ETS60991.1 - 5.1e-14 52.4 0.0 2.3e-13 50.2 0.0 2.2 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 ETS60991.1 - 1.3e-10 41.3 0.0 7.6e-10 38.8 0.0 2.4 2 1 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.24 ETS60991.1 - 3.2e-07 30.5 0.1 0.0058 16.8 0.0 2.9 3 0 0 3 3 3 2 PH domain PH_9 PF15410.1 ETS60991.1 - 8.3e-07 29.1 0.0 2.2e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Sld5 PF05916.6 ETS60992.1 - 7.7e-18 64.7 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein Acetyltransf_11 PF13720.1 ETS60992.1 - 0.16 12.2 0.0 0.36 11.0 0.0 1.6 1 1 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SNARE_assoc PF09335.6 ETS60993.1 - 6.4e-09 36.0 13.5 1.8e-08 34.5 6.1 2.9 2 1 0 2 2 2 2 SNARE associated Golgi protein Sugar_tr PF00083.19 ETS60994.1 - 1.4e-96 323.8 18.5 1.3e-55 188.7 2.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS60994.1 - 1.3e-25 89.9 31.3 2.4e-25 88.9 14.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS60994.1 - 0.00013 20.3 3.2 0.00023 19.5 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 ETS60994.1 - 0.056 13.5 5.7 0.14 12.2 2.9 2.5 2 0 0 2 2 2 0 Phage holin family 2 DIOX_N PF14226.1 ETS60997.1 - 5.6e-19 68.7 0.0 1.1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS60997.1 - 4.8e-14 52.4 0.0 9e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_15 PF01793.11 ETS60999.1 - 2.8e-132 440.6 4.7 3.5e-132 440.3 3.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 ETS61001.1 - 4.8e-66 216.4 23.4 1.7e-06 27.6 0.0 12.4 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 ETS61001.1 - 1.5e-20 73.1 0.7 2.4e-20 72.4 0.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 ETS61001.1 - 3.7e-09 35.2 2.2 0.082 11.0 0.1 6.4 4 2 1 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETS61001.1 - 4.8e-05 22.2 0.1 9.6 4.8 0.0 5.7 3 2 1 7 7 7 2 Nup133 N terminal like Maf PF02545.9 ETS61002.1 - 1.8e-43 147.9 0.0 2.2e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein CDV3 PF15359.1 ETS61004.1 - 0.13 12.3 2.2 0.21 11.6 1.5 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Glyoxal_oxid_N PF07250.6 ETS61005.1 - 1.5e-35 122.4 0.0 9e-34 116.6 0.0 3.2 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 ETS61005.1 - 5.8e-22 77.6 0.1 1.1e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 ETS61005.1 - 8.4e-05 22.2 5.1 0.21 11.3 0.1 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Reg_prop PF07494.6 ETS61005.1 - 0.053 13.5 0.3 20 5.6 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller CD99L2 PF12301.3 ETS61005.1 - 0.34 10.5 2.5 0.78 9.4 1.7 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 Arm PF00514.18 ETS61006.1 - 1.2e-60 199.4 27.5 4e-11 42.3 0.0 11.7 10 1 1 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS61006.1 - 1.2e-17 63.9 14.5 3.9e-05 23.8 0.0 7.6 3 1 5 8 8 7 7 HEAT repeats HEAT_EZ PF13513.1 ETS61006.1 - 4e-10 39.8 11.7 0.087 13.3 0.1 8.7 6 2 3 9 9 9 3 HEAT-like repeat HEAT PF02985.17 ETS61006.1 - 3.6e-09 35.9 21.1 2.7 8.2 0.0 10.0 12 0 0 12 12 11 3 HEAT repeat Adaptin_N PF01602.15 ETS61006.1 - 5.9e-09 34.7 5.7 2e-06 26.4 0.1 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 ETS61006.1 - 9.5e-09 33.7 0.2 1.5e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 ETS61006.1 - 1.8e-08 33.8 4.4 4e-05 22.8 0.5 3.0 1 1 2 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 ETS61006.1 - 6.1e-05 22.2 3.9 0.018 14.1 0.3 3.7 1 1 2 3 3 3 1 V-ATPase subunit H Sigma70_r3 PF04539.11 ETS61006.1 - 0.00085 19.1 0.1 0.044 13.6 0.0 3.3 3 0 0 3 3 3 1 Sigma-70 region 3 FeoC PF09012.5 ETS61006.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator V-ATPase_H_C PF11698.3 ETS61006.1 - 1.7 8.6 1.8 64 3.4 0.0 3.3 2 1 1 4 4 4 0 V-ATPase subunit H YqfD PF06898.6 ETS61006.1 - 4.1 5.9 0.0 6.1 5.4 0.0 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD COX6A PF02046.10 ETS61007.1 - 4.7e-32 110.3 0.3 4.9e-32 110.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Velvet PF11754.3 ETS61008.1 - 6.1e-65 218.6 0.0 9.2e-65 218.0 0.0 1.2 1 0 0 1 1 1 1 Velvet factor UPF0086 PF01868.11 ETS61009.1 - 5.1e-15 54.8 0.0 1.2e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function UPF0086 SAGA-Tad1 PF12767.2 ETS61009.1 - 2.5 7.7 7.7 2.4 7.7 4.1 1.7 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Catalase PF00199.14 ETS61010.1 - 4.4e-07 28.9 1.2 0.011 14.4 0.0 2.5 2 1 1 3 3 3 2 Catalase IFT46_B_C PF12317.3 ETS61010.1 - 0.079 12.3 1.0 0.14 11.5 0.4 1.5 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Polysacc_deac_1 PF01522.16 ETS61011.1 - 2.2e-20 72.5 0.0 7e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide deacetylase Macoilin PF09726.4 ETS61011.1 - 1.8 6.7 11.5 2.4 6.3 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein MRP-S25 PF13741.1 ETS61012.1 - 2.2e-65 220.3 1.1 2.4e-65 220.2 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 ETS61012.1 - 0.0001 22.1 0.2 0.31 10.9 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal protein S23 FH2 PF02181.18 ETS61013.1 - 1.8e-86 290.3 6.4 5.1e-86 288.8 0.0 2.7 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 ETS61013.1 - 1.3e-29 102.8 0.1 4.6e-21 75.0 0.0 3.6 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 ETS61013.1 - 8.2e-21 74.3 0.9 2.5e-20 72.7 0.6 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Glycos_transf_4 PF00953.16 ETS61013.1 - 0.3 10.8 0.0 0.55 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 AAA_13 PF13166.1 ETS61013.1 - 3 6.1 21.0 3e+02 -0.5 14.5 2.2 1 1 0 1 1 1 0 AAA domain Erp_C PF06780.6 ETS61013.1 - 3.2 7.6 9.4 0.79 9.5 0.1 3.6 3 1 1 4 4 4 0 Erp protein C-terminus TMF_DNA_bd PF12329.3 ETS61013.1 - 3.2 7.6 42.0 0.15 11.8 3.2 6.4 6 0 0 6 6 6 0 TATA element modulatory factor 1 DNA binding Pyr_redox_2 PF07992.9 ETS61014.1 - 3.5e-40 138.0 0.4 5.4e-40 137.4 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 ETS61014.1 - 1.5e-29 102.2 1.0 3.2e-29 101.1 0.7 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 ETS61014.1 - 4.4e-22 78.2 3.5 8.9e-19 67.6 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS61014.1 - 6.3e-12 45.9 0.0 1.2e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS61014.1 - 7.5e-06 24.6 3.9 0.14 10.5 0.0 3.2 2 1 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 ETS61014.1 - 3.2e-05 23.1 0.0 6.5e-05 22.1 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS61014.1 - 0.00079 18.4 0.0 0.0054 15.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS61014.1 - 0.0052 16.7 1.3 0.017 15.1 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 ETS61014.1 - 0.012 15.8 0.1 3.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.12 ETS61014.1 - 0.025 13.6 0.2 0.057 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 ETS61014.1 - 0.029 13.2 9.8 0.34 9.7 0.2 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS61014.1 - 0.076 11.8 4.5 0.11 11.3 2.2 1.9 2 0 0 2 2 2 0 FAD binding domain FtsJ PF01728.14 ETS61015.1 - 1.3e-46 158.8 0.0 2e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Porphobil_deam PF01379.15 ETS61016.1 - 9.8e-68 227.2 0.0 2.3e-63 213.0 0.0 2.5 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 ETS61016.1 - 2.6e-14 53.0 0.0 3.3e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain DUF848 PF05852.6 ETS61016.1 - 0.75 9.6 3.7 0.84 9.4 0.0 2.7 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) RNA_pol_Rpb2_6 PF00562.23 ETS61017.1 - 7.6e-113 377.1 0.0 1e-112 376.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 ETS61017.1 - 1.9e-26 92.2 0.0 2.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 ETS61017.1 - 1.3e-23 82.7 0.0 8.8e-23 80.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 ETS61017.1 - 1.7e-23 82.1 0.0 3.7e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 ETS61017.1 - 3.2e-19 69.1 0.0 5.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 ETS61017.1 - 2.8e-17 62.7 0.1 1.4e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 ETS61017.1 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF2981 PF11200.3 ETS61019.1 - 0.053 12.6 0.4 0.068 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) FAD_binding_7 PF03441.9 ETS61020.1 - 2.6e-62 210.5 1.7 4.2e-62 209.8 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS61020.1 - 3.5e-24 85.4 0.0 8.5e-24 84.1 0.0 1.6 1 1 0 1 1 1 1 DNA photolyase Lyase_8 PF02278.13 ETS61020.1 - 0.049 12.9 0.1 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain Tyrosinase PF00264.15 ETS61021.1 - 3.7e-16 59.9 2.2 5.5e-16 59.4 1.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2087 PF09860.4 ETS61021.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) YEATS PF03366.11 ETS61022.1 - 1.3e-32 111.3 0.1 4e-32 109.7 0.1 1.8 1 1 0 1 1 1 1 YEATS family KfrA_N PF11740.3 ETS61022.1 - 0.0061 17.0 0.1 0.0061 17.0 0.1 2.7 3 0 0 3 3 3 1 Plasmid replication region DNA-binding N-term ATP-synt_DE PF00401.15 ETS61022.1 - 0.026 14.4 2.9 0.071 13.0 2.0 1.8 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PPR_2 PF13041.1 ETS61023.1 - 1.2e-40 137.1 0.4 1.9e-13 50.1 0.0 8.2 6 1 1 7 7 7 4 PPR repeat family PPR PF01535.15 ETS61023.1 - 3.9e-33 111.1 1.0 0.00022 20.9 0.0 12.1 12 0 0 12 12 12 5 PPR repeat PPR_3 PF13812.1 ETS61023.1 - 1.2e-28 96.9 19.3 7e-05 22.7 0.0 12.7 14 0 0 14 14 14 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETS61023.1 - 1.2e-28 98.2 0.0 0.0013 18.1 0.0 7.9 7 0 0 7 7 7 6 PPR repeat ECSIT PF06239.6 ETS61023.1 - 0.00049 19.0 0.0 0.068 12.0 0.0 2.5 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_2 PF07719.12 ETS61023.1 - 0.00051 19.7 1.7 0.72 9.9 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 ETS61023.1 - 0.012 15.9 6.6 2.5 8.7 0.3 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS61023.1 - 0.013 15.4 8.3 8.1 6.4 0.0 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS61023.1 - 0.06 13.2 0.1 8.6 6.3 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF1310 PF07006.6 ETS61023.1 - 0.092 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) TPR_10 PF13374.1 ETS61023.1 - 0.25 11.3 4.8 2.3 8.2 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS61023.1 - 0.45 10.4 4.6 25 5.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MBOAT_2 PF13813.1 ETS61025.1 - 1.2e-06 28.5 4.4 3.7e-06 26.9 0.4 2.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Ribosomal_L14 PF00238.14 ETS61026.1 - 2.1e-44 150.1 0.9 2.3e-44 150.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e IKI3 PF04762.7 ETS61027.1 - 5.2e-275 914.8 0.0 6.9e-275 914.4 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Antimicrobial_1 PF08018.6 ETS61027.1 - 0.045 13.6 1.1 0.12 12.2 0.1 2.4 2 0 0 2 2 2 0 Frog antimicrobial peptide AAA_11 PF13086.1 ETS61028.1 - 1.2e-64 218.0 0.2 2.1e-64 217.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 ETS61028.1 - 4.7e-51 173.0 0.0 7.7e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS61028.1 - 1.5e-12 47.5 0.7 1.9e-10 40.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS61028.1 - 4.1e-11 42.4 5.0 6.3e-11 41.8 1.0 3.0 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 ETS61028.1 - 1.2e-09 38.0 0.1 0.046 13.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 ETS61028.1 - 8.1e-05 22.0 0.0 0.0019 17.5 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 ETS61028.1 - 0.00012 21.5 0.0 0.0003 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETS61028.1 - 0.00019 20.5 0.4 0.031 13.2 0.0 2.8 2 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 ETS61028.1 - 0.0002 21.4 0.1 0.0043 17.1 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 ETS61028.1 - 0.00031 20.8 0.0 0.0098 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 ETS61028.1 - 0.00093 18.4 0.0 1.6 7.9 0.0 2.6 3 0 0 3 3 3 2 PhoH-like protein DEAD PF00270.24 ETS61028.1 - 0.001 18.5 0.0 0.0041 16.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 ETS61028.1 - 0.0054 15.6 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 ETS61028.1 - 0.0084 16.3 1.0 0.036 14.2 0.2 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS61028.1 - 0.021 13.9 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETS61028.1 - 0.024 15.4 0.0 0.098 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS61028.1 - 0.033 14.1 5.5 0.017 15.0 1.4 2.4 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS61028.1 - 0.034 13.6 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Herpes_ori_bp PF02399.10 ETS61028.1 - 0.058 11.3 0.0 0.088 10.7 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Helicase_RecD PF05127.9 ETS61028.1 - 0.08 12.5 0.3 1.5 8.3 0.2 2.5 1 1 0 1 1 1 0 Helicase AAA_18 PF13238.1 ETS61028.1 - 0.088 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain FGF-BP1 PF06473.7 ETS61028.1 - 0.1 12.1 1.8 0.21 11.1 0.1 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) UvrD_C PF13361.1 ETS61028.1 - 0.12 11.8 0.0 1.6 8.1 0.1 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF258 PF03193.11 ETS61028.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 ETS61028.1 - 0.16 11.5 0.4 0.7 9.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS61028.1 - 0.23 11.6 0.0 0.52 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MitMem_reg PF13012.1 ETS61029.1 - 1.1e-36 125.4 0.1 2.1e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 ETS61029.1 - 1.4e-28 98.9 0.0 2.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PLDc_2 PF13091.1 ETS61030.1 - 3.3e-14 52.7 0.0 5.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 ETS61030.1 - 1.3e-07 31.1 1.3 0.012 15.4 0.1 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif IGPD PF00475.13 ETS61031.1 - 1.4e-59 200.1 0.4 2.4e-59 199.3 0.2 1.4 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase CoA_transf_3 PF02515.12 ETS61032.1 - 3.2e-28 98.2 2.0 1.2e-27 96.3 0.1 2.2 2 0 0 2 2 2 1 CoA-transferase family III FAM72 PF14976.1 ETS61036.1 - 1.8e-17 63.5 5.6 6e-17 61.8 3.9 1.8 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 ETS61036.1 - 0.082 12.9 7.8 0.61 10.1 0.0 2.6 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly UreF PF01730.11 ETS61039.1 - 1.9e-10 41.0 0.7 4.9e-10 39.7 0.5 1.7 1 1 0 1 1 1 1 UreF PEP_mutase PF13714.1 ETS61040.1 - 7.6e-40 136.6 1.1 9e-40 136.3 0.7 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ETS61040.1 - 1.3e-16 59.9 0.3 1.8e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PBP1_TM PF14812.1 ETS61041.1 - 0.0089 16.3 8.7 0.11 12.7 0.3 2.8 3 0 0 3 3 3 2 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3_PI4_kinase PF00454.22 ETS61042.1 - 1.6e-51 175.0 0.0 3.4e-51 173.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 ETS61042.1 - 3.6e-27 95.2 0.2 7.4e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 ETS61042.1 - 5e-26 90.7 0.0 2.8e-25 88.3 0.0 2.4 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 ETS61042.1 - 5.9e-11 41.5 1.1 9.5e-11 40.9 0.1 1.9 2 0 0 2 2 2 1 FATC domain TPR_11 PF13414.1 ETS61042.1 - 0.0038 16.8 1.3 0.014 15.0 0.0 2.7 3 0 0 3 3 3 1 TPR repeat PrkA PF06798.7 ETS61042.1 - 0.17 11.1 0.1 2.4 7.3 0.0 2.6 3 0 0 3 3 3 0 PrkA serine protein kinase C-terminal domain TPR_14 PF13428.1 ETS61042.1 - 0.26 12.0 0.0 0.26 12.0 0.0 4.9 6 1 1 7 7 7 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.15 ETS61043.1 - 2.2e-25 89.4 0.0 3.8e-25 88.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 ETS61043.1 - 0.26 11.0 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Daxx PF03344.10 ETS61043.1 - 0.31 9.4 3.8 0.47 8.8 2.6 1.2 1 0 0 1 1 1 0 Daxx Family DUF500 PF04366.7 ETS61044.1 - 2.6e-42 143.2 0.6 8.7e-42 141.5 0.1 2.0 2 1 0 2 2 2 1 Family of unknown function (DUF500) Antiterm PF03589.8 ETS61044.1 - 0.11 12.6 0.3 0.8 9.8 0.0 2.3 2 0 0 2 2 2 0 Antitermination protein Sec3_C PF09763.4 ETS61045.1 - 1.7e-195 651.2 0.0 2.2e-195 650.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 ETS61045.1 - 6.8e-25 86.7 0.1 1.3e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 ETS61045.1 - 1.9e-05 23.4 0.8 1.9e-05 23.4 0.5 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family PPR_2 PF13041.1 ETS61046.1 - 9e-25 86.4 0.0 3.6e-08 33.2 0.0 6.7 7 1 1 8 8 8 5 PPR repeat family PPR_3 PF13812.1 ETS61046.1 - 2.9e-20 70.7 9.4 0.0011 19.1 0.1 8.8 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 ETS61046.1 - 1e-14 53.3 1.7 0.0024 17.7 0.0 6.5 7 1 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 ETS61046.1 - 7.3e-09 34.9 1.9 0.00013 21.4 0.0 5.9 6 1 0 6 6 6 1 PPR repeat ABC_membrane_2 PF06472.10 ETS61047.1 - 1e-99 333.2 2.0 1.4e-99 332.7 1.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 ETS61047.1 - 2.5e-19 69.9 0.0 4.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS61047.1 - 0.00019 21.5 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 ETS61047.1 - 0.0073 16.6 0.2 0.064 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 ETS61047.1 - 0.024 13.2 0.0 0.04 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein SMC_N PF02463.14 ETS61047.1 - 0.026 13.7 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS61047.1 - 0.03 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS61047.1 - 0.032 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 ETS61047.1 - 0.13 11.9 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 ETS61047.1 - 0.17 10.5 0.0 0.34 9.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ATP-synt_DE_N PF02823.11 ETS61049.1 - 1.1e-15 57.0 0.2 1.9e-15 56.4 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Prefoldin PF02996.12 ETS61050.1 - 5.1e-26 90.6 1.8 9.9e-26 89.7 1.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit HN PF00423.14 ETS61050.1 - 0.02 13.1 1.2 0.032 12.5 0.8 1.2 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Rbsn PF11464.3 ETS61050.1 - 0.043 13.3 2.3 0.19 11.3 1.6 2.2 1 0 0 1 1 1 0 Rabenosyn Rab binding domain PPR_3 PF13812.1 ETS61050.1 - 0.34 11.2 6.3 10 6.7 0.0 4.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain RNA_pol_3_Rpc31 PF11705.3 ETS61051.1 - 0.0083 16.0 5.6 0.011 15.7 3.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FLO_LFY PF01698.11 ETS61051.1 - 0.025 13.4 5.3 0.029 13.2 3.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1509 PF07420.6 ETS61051.1 - 0.091 12.0 3.7 0.12 11.6 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Spt5_N PF11942.3 ETS61051.1 - 0.15 12.7 9.9 0.11 13.1 4.0 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pilt PF15453.1 ETS61051.1 - 0.39 10.3 8.6 0.59 9.7 5.9 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SR-25 PF10500.4 ETS61051.1 - 0.66 9.4 15.7 0.85 9.0 10.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-B_dimeris PF09026.5 ETS61051.1 - 1.3 9.3 7.0 2.2 8.5 4.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 ETS61051.1 - 1.6 6.6 6.5 1.6 6.6 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 ETS61051.1 - 2.3 6.7 8.6 2.6 6.6 5.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TATR PF03430.8 ETS61051.1 - 3.8 6.0 5.8 4.5 5.7 4.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3484 PF11983.3 ETS61051.1 - 4.4 8.1 7.0 8.2 7.3 3.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3484) RXT2_N PF08595.6 ETS61051.1 - 7.4 6.3 6.9 13 5.5 4.8 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal 3HCDH_N PF02737.13 ETS61052.1 - 1.6e-52 177.7 1.7 2.6e-52 177.1 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETS61052.1 - 4.1e-31 107.2 0.0 9.4e-31 106.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 ETS61052.1 - 4.5e-05 23.2 1.0 0.00014 21.5 0.8 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 ETS61052.1 - 0.0019 17.6 1.4 0.0077 15.6 0.6 2.2 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 ETS61052.1 - 0.013 15.3 3.8 0.053 13.3 1.8 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1104 PF06518.6 ETS61052.1 - 0.025 14.6 0.2 3.1 7.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) Saccharop_dh PF03435.13 ETS61052.1 - 0.028 13.4 2.3 0.05 12.5 1.6 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 ETS61052.1 - 0.029 14.7 4.1 0.64 10.4 2.8 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1188 PF06690.6 ETS61052.1 - 0.033 13.3 0.0 0.084 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) ThiF PF00899.16 ETS61052.1 - 0.083 12.7 0.9 0.16 11.8 0.6 1.4 1 0 0 1 1 1 0 ThiF family DapB_N PF01113.15 ETS61052.1 - 0.27 11.1 4.7 1.8 8.4 1.9 2.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus HA2 PF04408.18 ETS61053.1 - 6.4e-30 103.1 0.1 1.3e-29 102.2 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETS61053.1 - 3.3e-24 84.9 0.1 8.6e-24 83.5 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 ETS61053.1 - 1.6e-11 43.8 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS61053.1 - 2.7e-08 33.4 0.1 5.6e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS61053.1 - 2e-06 27.9 0.0 5.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 ETS61053.1 - 0.00076 19.3 0.2 0.016 15.0 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 ETS61053.1 - 0.0086 15.8 0.5 0.024 14.4 0.3 1.8 1 1 0 1 1 1 1 Flavivirus DEAD domain Myosin_head PF00063.16 ETS61053.1 - 0.0091 14.0 0.0 0.015 13.3 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_30 PF13604.1 ETS61053.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 ETS61053.1 - 0.041 13.3 0.6 0.25 10.7 0.4 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 ETS61053.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 ETS61053.1 - 0.086 12.0 0.0 0.57 9.3 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.22 ETS61053.1 - 0.14 12.4 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter VWA_2 PF13519.1 ETS61054.1 - 1e-10 42.0 0.0 2.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETS61054.1 - 1.6e-08 34.4 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Troponin PF00992.15 ETS61054.1 - 0.0017 18.3 0.1 0.0029 17.6 0.1 1.3 1 0 0 1 1 1 1 Troponin Med25_VWA PF11265.3 ETS61054.1 - 0.0042 16.1 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.13 ETS61054.1 - 0.2 10.4 0.0 0.68 8.7 0.0 1.7 1 1 0 1 1 1 0 Integrin, beta chain Arv1 PF04161.8 ETS61055.1 - 8.1e-14 52.0 0.0 2.4e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Arv1-like family Tom22 PF04281.8 ETS61056.1 - 2e-49 166.6 1.2 2.4e-49 166.3 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 ETS61056.1 - 0.19 11.2 3.5 0.31 10.6 2.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pho88 PF10032.4 ETS61057.1 - 5.6e-73 244.2 0.0 6.1e-73 244.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CK_II_beta PF01214.13 ETS61058.1 - 2.8e-81 271.4 0.0 3.5e-81 271.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Fcf2 PF08698.6 ETS61059.1 - 2e-18 66.2 0.3 4.7e-16 58.6 0.1 2.8 2 0 0 2 2 2 2 Fcf2 pre-rRNA processing DNA_pol_phi PF04931.8 ETS61059.1 - 3.9 5.1 12.4 5.9 4.5 8.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi Sas10 PF09368.5 ETS61060.1 - 1.9e-26 91.9 3.2 1.9e-26 91.9 2.2 2.7 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 ETS61060.1 - 6e-10 39.1 0.1 1.8e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ras_bdg_2 PF14847.1 ETS61060.1 - 1 9.3 5.5 2.3 8.1 0.0 3.7 4 0 0 4 4 4 0 Ras-binding domain of Byr2 Thiolase_N PF00108.18 ETS61061.1 - 1e-76 257.4 0.1 2.2e-76 256.3 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS61061.1 - 1.4e-45 153.6 0.4 2.6e-45 152.8 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 ETS61061.1 - 8.3e-05 22.1 0.5 0.00086 18.8 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 ETS61061.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BRCA-2_helical PF09169.5 ETS61061.1 - 0.0096 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 BRCA2, helical ACP_syn_III PF08545.5 ETS61061.1 - 0.038 13.6 2.3 0.12 12.0 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4358 PF14270.1 ETS61061.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) DUF2093 PF09866.4 ETS61061.1 - 0.12 11.5 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) GP41 PF00517.12 ETS61062.1 - 3.4 7.1 0.1 5 6.6 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Ubie_methyltran PF01209.13 ETS61063.1 - 2.8e-73 245.8 0.2 2.9e-38 131.2 0.0 2.6 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS61063.1 - 7.7e-12 45.5 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS61063.1 - 2.4e-11 43.4 0.0 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 ETS61063.1 - 2.1e-10 40.5 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS61063.1 - 2.9e-10 40.4 0.0 1.3e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETS61063.1 - 9.5e-08 32.6 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS61063.1 - 7.7e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS61063.1 - 6.1e-06 26.2 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 ETS61063.1 - 0.0029 17.2 0.0 0.014 15.0 0.0 2.1 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_28 PF02636.12 ETS61063.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 ETS61063.1 - 0.1 11.9 0.0 0.97 8.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Cullin PF00888.17 ETS61064.1 - 2.4e-186 620.7 2.5 3.1e-186 620.4 1.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 ETS61064.1 - 8.1e-28 96.0 4.5 2.6e-27 94.4 1.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain GntR PF00392.16 ETS61064.1 - 0.011 15.1 0.0 0.25 10.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Penicillinase_R PF03965.11 ETS61064.1 - 0.056 13.5 9.9 3.5 7.7 0.1 5.2 4 2 2 6 6 6 0 Penicillinase repressor HTH_27 PF13463.1 ETS61064.1 - 0.093 13.0 1.5 15 5.9 0.0 3.7 4 0 0 4 4 4 0 Winged helix DNA-binding domain AAA_23 PF13476.1 ETS61066.1 - 8.1e-26 91.5 0.1 8.1e-26 91.5 0.1 8.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 ETS61066.1 - 1.4e-12 48.1 4.8 6.7e-08 32.8 0.3 3.0 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.1 ETS61066.1 - 6e-11 41.5 124.8 0.00012 20.7 0.0 6.6 2 1 4 6 6 6 4 AAA domain SbcCD_C PF13558.1 ETS61066.1 - 1.4e-10 40.9 0.0 4.3e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 ETS61066.1 - 7.8e-09 35.0 31.3 3.1e-07 29.8 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Myosin_tail_1 PF01576.14 ETS61066.1 - 1.2e-06 26.5 69.0 1.2e-06 26.5 47.8 2.2 2 0 0 2 2 2 1 Myosin tail AAA_15 PF13175.1 ETS61066.1 - 0.00064 18.8 33.5 0.0016 17.5 7.8 4.3 3 2 1 4 4 4 2 AAA ATPase domain Tropomyosin_1 PF12718.2 ETS61066.1 - 0.0057 16.5 20.8 0.0057 16.5 14.4 8.9 4 3 4 8 8 8 2 Tropomyosin like AAA_29 PF13555.1 ETS61066.1 - 0.014 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 ETS61066.1 - 0.04 13.6 1.9 0.31 10.7 0.0 3.5 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B zf-DHHC PF01529.15 ETS61067.1 - 1.6e-40 138.3 2.1 1.6e-40 138.3 1.4 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 ETS61067.1 - 1.9 8.3 10.1 0.28 11.0 3.3 2.1 2 0 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 ETS61068.1 - 6.7e-06 25.5 0.2 1.2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Auto_anti-p27 PF06677.7 ETS61068.1 - 0.046 13.5 0.9 0.094 12.4 0.6 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ThiF PF00899.16 ETS61069.1 - 1.4e-09 37.9 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family Aminotran_3 PF00202.16 ETS61070.1 - 9.7e-83 277.8 0.0 1.2e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ETS61070.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Pkinase PF00069.20 ETS61071.1 - 5.6e-35 120.7 0.0 3e-34 118.3 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61071.1 - 2.8e-10 39.7 0.0 1.4e-09 37.4 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS61071.1 - 5.3e-05 22.3 0.0 9.4e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SCP2 PF02036.12 ETS61072.1 - 1.8e-10 40.9 0.0 3.9e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 ETS61072.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Tropomyosin_1 PF12718.2 ETS61073.1 - 0.013 15.3 6.4 0.013 15.3 4.4 1.8 2 0 0 2 2 2 0 Tropomyosin like PYC_OADA PF02436.13 ETS61073.1 - 0.076 12.4 0.4 0.21 10.9 0.1 1.8 1 1 0 1 1 1 0 Conserved carboxylase domain DUF2730 PF10805.3 ETS61073.1 - 0.28 10.9 2.6 0.66 9.7 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4200 PF13863.1 ETS61073.1 - 0.59 10.0 10.1 0.034 14.0 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 ETS61073.1 - 1.6 8.2 10.4 0.049 13.2 0.8 2.8 4 0 0 4 4 4 0 IncA protein SlyX PF04102.7 ETS61073.1 - 7.9 6.9 9.6 0.32 11.3 1.3 2.7 3 0 0 3 3 3 0 SlyX GRASP55_65 PF04495.9 ETS61074.1 - 7.4e-68 226.8 0.0 2.3e-55 186.3 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 ETS61074.1 - 0.019 14.8 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.19 ETS61074.1 - 0.037 14.1 0.0 8 6.7 0.0 2.4 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) DUF159 PF02586.9 ETS61075.1 - 6.9e-52 175.9 0.0 1.1e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Cnd2 PF05786.9 ETS61076.1 - 0.22 9.9 4.3 0.36 9.2 3.0 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 PGA2 PF07543.7 ETS61076.1 - 0.27 11.0 7.2 0.58 9.9 5.0 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 PBP1_TM PF14812.1 ETS61076.1 - 0.63 10.3 8.6 1.5 9.1 6.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 2-Hacid_dh_C PF02826.14 ETS61077.1 - 5e-59 198.4 0.0 7.3e-59 197.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS61077.1 - 4.4e-20 71.4 0.1 5e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS61077.1 - 1e-07 31.9 0.1 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS61077.1 - 2.5e-05 24.5 0.0 7.3e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 ETS61077.1 - 0.00097 18.5 0.2 0.0036 16.6 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 ETS61077.1 - 0.011 15.6 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS61077.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding CMAS PF02353.15 ETS61078.1 - 1.5e-61 207.8 0.2 1.9e-61 207.5 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 ETS61078.1 - 1.4e-13 50.9 0.0 1.2e-11 44.6 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS61078.1 - 6.7e-11 42.5 0.0 6.6e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS61078.1 - 1.4e-06 27.9 0.0 3.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS61078.1 - 7.5e-06 25.9 0.0 4.3e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS61078.1 - 2e-05 25.0 0.0 8.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS61078.1 - 2.7e-05 24.5 0.0 8e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 ETS61078.1 - 3.9e-05 23.0 0.0 0.00031 20.1 0.0 2.0 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 ETS61078.1 - 0.00011 22.5 0.0 0.00034 20.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS61078.1 - 0.00095 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 ETS61078.1 - 0.0069 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 ETS61078.1 - 0.047 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bax1-I PF01027.15 ETS61079.1 - 6.9e-45 153.1 27.6 8.1e-45 152.9 19.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 ETS61079.1 - 1 8.9 24.5 8.3 6.0 7.6 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4131 PF13567.1 ETS61079.1 - 1.2 8.5 13.4 0.7 9.2 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_S16 PF00886.14 ETS61080.1 - 6.8e-29 99.3 0.3 1.2e-28 98.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S16 Lon_C PF05362.8 ETS61082.1 - 1.3e-66 223.8 0.1 2.8e-66 222.7 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 ETS61082.1 - 3.6e-34 118.2 0.1 1e-33 116.7 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 ETS61082.1 - 4e-21 75.5 0.0 1.1e-20 74.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 ETS61082.1 - 5e-07 29.2 0.0 1.6e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 ETS61082.1 - 3.1e-06 26.9 0.0 7.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETS61082.1 - 1.3e-05 25.1 0.0 3.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETS61082.1 - 1.9e-05 24.7 0.1 0.00044 20.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 ETS61082.1 - 3.3e-05 22.7 0.0 5.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 ETS61082.1 - 0.0012 19.0 0.0 0.032 14.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS61082.1 - 0.0012 19.6 0.0 0.0039 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS61082.1 - 0.0023 17.8 0.0 0.0065 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS61082.1 - 0.0082 15.2 0.0 0.039 12.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 ETS61082.1 - 0.01 16.1 0.0 0.01 16.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 ETS61082.1 - 0.017 14.5 0.1 0.054 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS61082.1 - 0.04 13.1 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 ETS61082.1 - 0.042 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 ETS61082.1 - 0.054 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 ETS61082.1 - 0.39 9.3 4.8 0.72 8.4 0.1 2.6 3 0 0 3 3 3 0 TIP49 C-terminus ADH_zinc_N PF00107.21 ETS61083.1 - 9.2e-22 76.9 0.0 1.6e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS61083.1 - 2.1e-09 37.1 0.0 5.5e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS61083.1 - 4.3e-05 24.4 0.3 0.00017 22.4 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 ETS61083.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 ETS61083.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 ETS61083.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_clus PF00172.13 ETS61086.1 - 1.5e-09 37.6 7.7 2.4e-09 36.9 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRC_subunit PF08624.5 ETS61087.1 - 2.2e-45 154.0 0.1 6.5e-45 152.4 0.0 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit RhoGAP PF00620.22 ETS61089.1 - 9.8e-45 151.8 0.1 1.6e-44 151.2 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 ETS61089.1 - 1.9e-12 47.2 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PX PF00787.19 ETS61089.1 - 2e-07 30.7 0.0 5.9e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 PX domain PH_11 PF15413.1 ETS61089.1 - 2e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain HicB PF05534.7 ETS61089.1 - 0.035 13.6 0.9 0.091 12.3 0.6 1.7 1 0 0 1 1 1 0 HicB family UPF0047 PF01894.12 ETS61090.1 - 3.9e-40 136.3 0.0 5.4e-40 135.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 TMEM89 PF15098.1 ETS61090.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 TMEM89 protein family DuoxA PF10204.4 ETS61090.1 - 0.085 11.8 0.2 0.89 8.5 0.0 2.0 1 1 0 2 2 2 0 Dual oxidase maturation factor PRMT5 PF05185.11 ETS61091.1 - 4.7e-150 500.4 0.0 5.9e-150 500.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 ETS61091.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SPT2 PF08243.6 ETS61092.1 - 1.4e-17 64.0 21.1 1.4e-17 64.0 14.6 5.9 4 3 2 6 6 6 1 SPT2 chromatin protein Acetyltransf_1 PF00583.19 ETS61093.1 - 6.5e-13 48.5 0.0 2.3e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS61093.1 - 5.4e-08 32.8 0.4 5.5e-07 29.6 0.1 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS61093.1 - 1.2e-05 24.9 0.1 0.0034 17.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.1 ETS61093.1 - 0.00013 22.0 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS61093.1 - 0.0068 16.3 0.1 0.65 9.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS61093.1 - 0.0099 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS61093.1 - 0.014 15.2 0.0 0.18 11.6 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 ETS61093.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.1 ETS61093.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase_2 PF12681.2 ETS61093.1 - 0.14 12.8 0.0 1 9.9 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain CNH PF00780.17 ETS61094.1 - 3.2e-66 223.5 0.0 5.8e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 ETS61094.1 - 6e-30 104.4 0.0 1.1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Pkinase PF00069.20 ETS61094.1 - 3.1e-20 72.4 0.0 4.8e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 ETS61094.1 - 4e-15 55.0 10.9 1.3e-10 40.7 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT PF02985.17 ETS61094.1 - 2.8e-10 39.3 3.8 0.027 14.5 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat Pkinase_Tyr PF07714.12 ETS61094.1 - 5.1e-09 35.5 0.0 5.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH_5 PF15405.1 ETS61094.1 - 4.2e-07 29.9 0.0 4.9e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 ETS61094.1 - 0.019 13.9 0.0 3 6.7 0.0 2.4 2 0 0 2 2 2 0 Kinase-like DEP PF00610.16 ETS61094.1 - 0.043 13.5 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Actin PF00022.14 ETS61095.1 - 8.7e-94 314.1 0.0 1.1e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Actin PLA2_B PF01735.13 ETS61096.1 - 1.2e-142 475.5 2.0 1.5e-142 475.2 1.4 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 ETS61096.1 - 0.00091 19.2 0.5 0.00091 19.2 0.4 3.4 4 0 0 4 4 4 1 Patatin-like phospholipase DUF4207 PF13904.1 ETS61096.1 - 0.058 12.7 2.5 0.11 11.8 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) CDP-OH_P_transf PF01066.16 ETS61097.1 - 8.9e-15 54.8 4.1 8.9e-15 54.8 2.8 3.2 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase NAD_binding_9 PF13454.1 ETS61098.1 - 6.5e-05 22.7 0.0 0.0003 20.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS61098.1 - 0.00089 19.3 0.0 3 7.8 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS61098.1 - 0.073 11.5 0.3 0.18 10.2 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 ETS61098.1 - 0.081 12.7 0.0 0.83 9.4 0.0 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS61098.1 - 0.098 12.6 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4142 PF13628.1 ETS61098.1 - 0.12 12.3 2.3 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) K_oxygenase PF13434.1 ETS61098.1 - 0.19 10.6 0.1 4.9 5.9 0.0 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Aminotran_3 PF00202.16 ETS61099.1 - 2.2e-101 339.1 0.2 3.9e-101 338.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Fork_head PF00250.13 ETS61099.1 - 9.4e-31 105.7 0.1 2.1e-30 104.6 0.1 1.5 1 0 0 1 1 1 1 Fork head domain Aminotran_1_2 PF00155.16 ETS61099.1 - 0.002 17.1 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II Orn_Arg_deC_N PF02784.11 ETS61101.1 - 5.7e-70 235.3 0.0 7.7e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 ETS61101.1 - 3e-30 104.3 0.0 4.6e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MFS_1 PF07690.11 ETS61102.1 - 7.2e-33 113.7 38.5 4.9e-32 111.0 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS61102.1 - 6.3e-10 38.2 26.2 1.9e-09 36.6 18.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS61102.1 - 0.007 14.6 5.2 0.011 13.9 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPT PF03151.11 ETS61103.1 - 1.1e-11 44.5 5.2 1.1e-11 44.5 3.6 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 ETS61103.1 - 1.9e-11 43.4 14.3 1.6e-07 30.5 0.6 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 ETS61103.1 - 0.093 12.7 24.4 0.028 14.4 2.9 2.4 2 0 0 2 2 2 0 EamA-like transporter family SHR3_chaperone PF08229.6 ETS61104.1 - 5.1e-38 130.0 1.3 1.1e-37 128.8 0.9 1.6 1 1 0 1 1 1 1 ER membrane protein SH3 Neurensin PF14927.1 ETS61104.1 - 0.23 10.8 2.6 1.1 8.6 0.2 2.3 1 1 1 2 2 2 0 Neurensin Clat_adaptor_s PF01217.15 ETS61105.1 - 4.3e-49 165.8 0.1 7.2e-36 123.0 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Mito_carr PF00153.22 ETS61106.1 - 3.7e-71 234.9 5.3 1.4e-23 82.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 ETS61106.1 - 0.062 12.6 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Penicillin-binding protein Tp47 domain a OrfB_Zn_ribbon PF07282.6 ETS61107.1 - 7.2e-09 35.1 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.14 ETS61107.1 - 8e-06 25.4 0.2 2.3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Probable transposase FecR PF04773.8 ETS61107.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 FecR protein Ribosomal_S13 PF00416.17 ETS61108.1 - 3.7e-39 133.4 0.6 4.8e-39 133.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 ETS61108.1 - 0.0043 17.0 0.0 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 Helix-hairpin-helix motif FbpA PF05833.6 ETS61108.1 - 0.0052 15.3 0.0 0.006 15.1 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) MMS22L_C PF14911.1 ETS61110.1 - 0.26 10.3 0.1 0.59 9.1 0.0 1.5 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal CPSase_L_D2 PF02786.12 ETS61111.1 - 5.7e-82 274.0 0.1 9.1e-82 273.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 ETS61111.1 - 2.2e-67 226.3 0.0 3.8e-67 225.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 ETS61111.1 - 1.5e-35 121.6 0.0 5.7e-35 119.7 0.0 2.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 ETS61111.1 - 1.1e-29 103.8 0.0 1.8e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 ETS61111.1 - 2e-29 101.7 0.0 4.4e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 ETS61111.1 - 3.2e-20 72.6 0.1 5.7e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS61111.1 - 7.9e-16 57.6 0.0 2e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 ETS61111.1 - 1.5e-15 56.5 1.0 3e-15 55.5 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 ETS61111.1 - 1.7e-14 53.2 0.1 6.7e-06 25.6 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 ETS61111.1 - 2.1e-09 37.0 0.0 3.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 ETS61111.1 - 6.8e-08 32.1 0.0 0.004 16.5 0.0 2.4 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 ETS61111.1 - 1.5e-07 30.8 0.0 3.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 ETS61111.1 - 3.3e-06 26.7 0.0 1.4e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 ETS61111.1 - 3.1e-05 23.9 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 ETS61111.1 - 0.00044 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 ETS61111.1 - 0.0016 18.7 0.1 1 9.7 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 ETS61111.1 - 0.0065 15.6 0.1 0.078 12.1 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 ETS61111.1 - 0.014 14.5 0.6 0.034 13.3 0.1 1.7 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GATA PF00320.22 ETS61112.1 - 2.4e-31 106.7 18.8 1.3e-15 56.4 2.9 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 ETS61112.1 - 1.3e-05 24.3 5.6 0.04 13.2 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 ETS61112.1 - 0.0091 15.4 6.8 0.82 9.2 0.3 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 ETS61112.1 - 0.028 14.3 1.6 3.5 7.6 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain ArfGap PF01412.13 ETS61112.1 - 0.14 11.9 4.6 3.9 7.3 0.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zinc_ribbon_4 PF13717.1 ETS61112.1 - 0.26 11.0 2.0 8.8 6.1 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ETS61112.1 - 0.28 10.7 1.8 7.8 6.1 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 ETS61112.1 - 0.47 10.0 12.1 0.53 9.8 0.4 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Auto_anti-p27 PF06677.7 ETS61112.1 - 1.4 8.7 3.5 25 4.7 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 ETS61112.1 - 7.5 6.2 5.3 11 5.6 0.7 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Acyl-CoA_dh_1 PF00441.19 ETS61115.1 - 3.3e-51 173.3 2.5 6.4e-51 172.3 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS61115.1 - 1.1e-25 90.4 0.8 2.1e-25 89.5 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETS61115.1 - 1.5e-23 82.0 0.3 3.2e-23 80.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS61115.1 - 2.9e-19 69.6 2.8 2.9e-19 69.6 1.9 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 ETS61115.1 - 1.3e-06 28.0 0.5 5.9e-06 25.8 0.3 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal FAD-oxidase_C PF02913.14 ETS61116.1 - 5.3e-53 179.8 0.0 9.2e-53 179.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS61116.1 - 1.1e-32 112.3 0.0 2.1e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Polysacc_synt_4 PF04669.8 ETS61116.1 - 4.7e-22 78.2 0.7 1.6e-21 76.5 0.5 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF3918 PF13056.1 ETS61116.1 - 0.053 12.8 0.5 0.11 11.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) AICARFT_IMPCHas PF01808.13 ETS61117.1 - 9.6e-111 369.8 0.2 1.4e-110 369.3 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 ETS61117.1 - 4.9e-22 77.6 0.0 1.1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain Phage_int_SAM_1 PF02899.12 ETS61117.1 - 0.048 13.8 0.3 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DPBB_1 PF03330.13 ETS61118.1 - 8.3e-06 25.7 0.1 9.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 ETS61118.1 - 0.0076 15.9 0.3 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Barwin family DUF3735 PF12537.3 ETS61118.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) E1-E2_ATPase PF00122.15 ETS61120.1 - 6.1e-37 126.8 0.0 1.3e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETS61120.1 - 1.6e-29 103.8 1.2 2.8e-29 103.0 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 ETS61120.1 - 1.7e-16 60.1 7.1 2.3e-05 24.4 0.0 5.2 4 1 0 4 4 4 3 Heavy-metal-associated domain HAD PF12710.2 ETS61120.1 - 1.5e-15 57.9 0.0 1.8e-14 54.3 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS61120.1 - 0.0033 17.0 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.16 ETS61121.1 - 3.1e-44 150.9 0.3 5.3e-44 150.1 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF730 PF05325.6 ETS61121.1 - 0.049 13.4 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF730) DUF3336 PF11815.3 ETS61122.1 - 1.7e-41 141.1 1.3 3.1e-41 140.2 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 ETS61122.1 - 1.1e-19 71.1 0.3 3e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2361 PF10153.4 ETS61123.1 - 7e-20 71.3 10.0 7e-20 71.3 6.9 2.7 2 2 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) 6PF2K PF01591.13 ETS61124.1 - 5.8e-61 205.4 0.0 8e-61 204.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 ETS61124.1 - 2.2e-22 79.8 0.0 4.2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 ETS61124.1 - 0.0028 18.4 0.4 0.013 16.2 0.0 2.4 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 ETS61124.1 - 0.054 13.3 0.3 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.15 ETS61125.1 - 8.1e-21 73.6 0.0 1.1e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS61125.1 - 0.0015 18.7 0.0 0.0055 16.8 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 ETS61125.1 - 0.042 13.8 0.0 0.099 12.6 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin DBR1 PF05011.8 ETS61126.1 - 2.4e-21 76.1 0.0 1.2e-19 70.5 0.0 2.3 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 ETS61126.1 - 1.8e-08 34.0 0.1 3.1e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS61126.1 - 9.7e-06 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glycogen_syn PF05693.8 ETS61128.1 - 0 1104.2 0.0 0 1103.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 ETS61128.1 - 2.2e-08 33.6 0.0 3.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 ETS61128.1 - 6.6e-08 32.3 0.3 4.7e-07 29.5 0.2 2.2 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 ETS61128.1 - 8.5e-07 29.2 0.3 1.6e-06 28.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF1744 PF08490.7 ETS61130.1 - 1.5e-118 395.8 0.0 2.3e-118 395.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 ETS61130.1 - 3.1e-66 223.4 0.0 5.8e-66 222.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 ETS61130.1 - 1.2e-22 80.3 0.2 7.1e-22 77.8 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 ETS61130.1 - 7.6e-10 38.6 0.0 2.8e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 ETS61130.1 - 1.2e-05 25.1 0.0 5.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily Asparaginase PF00710.15 ETS61131.1 - 6.3e-147 488.4 0.0 8.2e-147 488.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 ETS61131.1 - 2.1e-12 47.2 0.1 5.4e-12 45.8 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS61131.1 - 6.8e-12 44.5 1.1 4.1e-05 23.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 ETS61131.1 - 2.9e-06 26.9 0.1 0.13 12.5 0.1 3.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETS61131.1 - 1.1e-05 25.8 0.1 5.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS61131.1 - 0.0008 19.5 1.0 0.0095 16.1 0.0 3.3 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Pex14_N PF04695.8 ETS61131.1 - 0.0084 16.1 0.5 0.022 14.8 0.0 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_binding_10 PF13460.1 ETS61132.1 - 1.9e-08 34.5 0.1 2.9e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS61132.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 ETS61132.1 - 0.0056 16.9 0.1 0.015 15.6 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Germane PF10646.4 ETS61132.1 - 0.092 12.9 0.5 3.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Sporulation and spore germination Citrate_synt PF00285.16 ETS61133.1 - 8.7e-18 64.1 0.1 2.2e-15 56.2 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 ETS61133.1 - 4e-15 55.7 0.1 8.2e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 ETS61133.1 - 1.1e-12 48.2 0.0 4.1e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 ETS61133.1 - 7.3e-06 25.6 0.0 3.2e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DUF2372 PF10178.4 ETS61135.1 - 0.00081 19.4 0.0 0.0018 18.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) FHA PF00498.21 ETS61136.1 - 0.00087 19.3 0.0 0.0054 16.8 0.0 2.3 2 1 0 2 2 2 1 FHA domain VHS PF00790.14 ETS61137.1 - 4.8e-40 136.4 0.0 1.4e-39 134.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 ETS61137.1 - 4.4e-24 84.3 0.0 1e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 GAT domain ThiF PF00899.16 ETS61138.1 - 7.2e-40 135.9 0.1 1.7e-39 134.7 0.0 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 ETS61138.1 - 1.1e-26 92.1 0.1 3.7e-26 90.4 0.2 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 ETS61138.1 - 6.5e-22 76.6 3.2 1.1e-21 75.8 2.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 ETS61138.1 - 5.1e-10 39.3 0.8 1.3e-09 37.9 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 ETS61138.1 - 0.00054 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETS61138.1 - 0.0059 16.9 0.3 0.33 11.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.18 ETS61138.1 - 0.007 16.2 0.6 0.13 12.0 0.1 2.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 ETS61138.1 - 0.032 14.4 0.2 0.096 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding RRM_1 PF00076.17 ETS61139.1 - 2.1e-16 59.2 0.0 3.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS61139.1 - 6.8e-10 38.7 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 ETS61139.1 - 2.7e-06 27.7 1.3 2.7e-06 27.7 0.9 2.4 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 ETS61139.1 - 5.9e-06 26.0 0.0 9.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS61139.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif CBS PF00571.23 ETS61140.1 - 4.7e-12 45.5 2.3 3.6e-06 26.6 0.2 4.4 4 0 0 4 4 4 3 CBS domain DASH_Ask1 PF08655.5 ETS61141.1 - 2.7e-28 97.5 0.1 5e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 IF-2B PF01008.12 ETS61142.1 - 5.4e-56 189.6 0.5 1.6e-49 168.4 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family TFIIA PF03153.8 ETS61142.1 - 0.0082 16.0 1.0 0.011 15.6 0.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 ETS61142.1 - 0.009 16.2 7.4 0.019 15.1 5.1 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.1 ETS61142.1 - 0.024 14.9 5.8 0.044 14.0 4.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 ETS61142.1 - 0.057 13.0 5.9 0.1 12.1 4.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Serglycin PF04360.7 ETS61142.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 1 0 Serglycin CDC45 PF02724.9 ETS61142.1 - 0.13 10.3 4.2 0.17 9.8 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETS61142.1 - 0.47 10.2 3.5 0.81 9.4 2.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 ETS61142.1 - 1.3 8.5 11.4 2.5 7.6 7.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 ETS61142.1 - 1.4 7.5 15.6 2.1 6.9 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 ETS61142.1 - 1.8 7.7 10.9 2.6 7.2 7.6 1.1 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 ETS61142.1 - 3.2 6.6 5.8 4.6 6.1 4.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.3 ETS61142.1 - 3.7 7.4 13.3 6.1 6.7 9.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.7 ETS61142.1 - 7.8 6.1 12.3 14 5.3 8.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BTV_NS2 PF04514.7 ETS61142.1 - 9.4 5.0 6.5 14 4.4 4.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pex24p PF06398.6 ETS61143.1 - 1.9e-05 23.6 7.1 3e-05 23.0 4.9 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SPT6_acidic PF14632.1 ETS61144.1 - 0.0095 16.0 7.3 0.0095 16.0 5.0 5.6 4 2 1 5 5 5 2 Acidic N-terminal SPT6 SAM_decarbox PF01536.11 ETS61145.1 - 1.1e-76 257.7 0.0 2.1e-44 151.5 0.0 2.7 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase DUF4201 PF13870.1 ETS61147.1 - 0.001 18.5 5.3 0.001 18.5 3.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) ATG16 PF08614.6 ETS61147.1 - 0.0026 17.6 9.8 0.0026 17.6 6.8 2.8 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) EzrA PF06160.7 ETS61147.1 - 0.084 11.0 6.5 1 7.4 2.7 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 ETS61147.1 - 1.5 9.1 11.9 3.5 7.9 2.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 ETS61147.1 - 2 7.9 20.0 0.055 13.0 5.5 2.9 3 0 0 3 3 3 0 IncA protein Tyr-DNA_phospho PF06087.7 ETS61149.1 - 3.8e-33 114.7 0.0 6.9e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCCH PF00642.19 ETS61149.1 - 0.081 12.6 4.8 0.033 13.8 1.3 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 ETS61149.1 - 0.22 11.2 2.2 4.8 6.8 0.1 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase DUF1906 PF08924.6 ETS61149.1 - 0.3 10.9 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) Ras PF00071.17 ETS61150.1 - 3.9e-58 195.4 0.1 4.7e-58 195.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS61150.1 - 2.6e-20 73.1 0.1 3.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61150.1 - 4.7e-09 35.7 0.0 5.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS61150.1 - 4.8e-07 29.4 0.0 9e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS61150.1 - 0.0046 16.9 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS61150.1 - 0.0078 15.5 0.0 0.021 14.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 ETS61150.1 - 0.02 14.4 1.4 0.23 10.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 ETS61150.1 - 0.034 13.2 0.1 0.05 12.7 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ser_hydrolase PF06821.8 ETS61150.1 - 0.067 12.7 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Csm1 PF12539.3 ETS61151.1 - 0.0021 18.4 0.0 0.0073 16.7 0.0 1.9 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 HrpA_pilin PF09589.5 ETS61151.1 - 0.13 12.7 7.4 16 5.9 5.1 3.4 1 1 0 1 1 1 0 HrpA pilus formation protein Med28 PF11594.3 ETS61151.1 - 0.51 10.5 7.0 1.7 8.8 0.1 2.9 2 0 0 2 2 2 0 Mediator complex subunit 28 DUF2852 PF11014.3 ETS61151.1 - 0.83 9.6 6.0 1 9.3 2.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) YlqD PF11068.3 ETS61151.1 - 4.3 7.3 11.0 7.1 6.6 1.4 2.5 2 0 0 2 2 2 0 YlqD protein MOSC_N PF03476.11 ETS61152.1 - 5.8e-21 74.4 0.0 1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 ETS61152.1 - 9.9e-09 34.7 0.0 1.6e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 MOSC domain Glyco_tran_28_C PF04101.11 ETS61153.1 - 2.2e-19 69.7 0.0 5e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Tape_meas_lam_C PF09718.5 ETS61153.1 - 0.0055 16.6 0.9 0.0055 16.6 0.6 2.1 2 0 0 2 2 2 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Herpes_gE PF02480.11 ETS61154.1 - 0.0052 15.1 0.0 0.013 13.8 0.0 1.6 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MtrF PF09472.5 ETS61154.1 - 0.18 11.0 1.0 0.44 9.8 0.7 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.1 ETS61154.1 - 0.35 11.2 0.0 0.75 10.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UQ_con PF00179.21 ETS61156.1 - 3.5e-52 175.5 0.0 4e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS61156.1 - 6.2e-05 22.7 0.0 7.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS61156.1 - 0.0007 19.4 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 ETS61156.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Skp1_POZ PF03931.10 ETS61157.1 - 5.7e-10 39.1 0.0 4e-09 36.4 0.0 2.2 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain RNase_PH PF01138.16 ETS61158.1 - 4e-11 43.3 0.0 6.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETS61158.1 - 2.7e-08 33.6 0.0 7.1e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF3602 PF12223.3 ETS61159.1 - 1.9e-19 69.8 26.0 2.8e-16 59.6 5.1 4.2 1 1 3 4 4 4 3 Protein of unknown function (DUF3602) EF-hand_6 PF13405.1 ETS61160.1 - 5.5e-15 53.8 1.0 3.2e-06 26.5 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 ETS61160.1 - 3.3e-14 52.7 0.1 4e-08 33.2 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS61160.1 - 2.8e-12 44.9 1.9 1.1e-05 24.3 0.0 3.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 ETS61160.1 - 5.9e-07 29.0 0.4 0.00065 19.2 0.0 3.6 1 1 3 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.1 ETS61160.1 - 7.7e-06 25.7 0.0 0.00081 19.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETS61160.1 - 1.1e-05 24.5 3.7 0.0051 16.0 0.3 2.9 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.5 ETS61160.1 - 0.00082 19.3 0.0 0.29 11.1 0.0 2.5 2 1 0 2 2 2 2 Ca2+ insensitive EF hand UPF0154 PF03672.8 ETS61160.1 - 0.045 13.3 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) RNA_pol_Rpb4 PF03874.11 ETS61160.1 - 0.048 13.6 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 Big_3_2 PF12245.3 ETS61160.1 - 0.071 12.6 0.4 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) ATP-synt_G PF04718.10 ETS61161.1 - 2.5e-20 73.0 0.3 4.3e-20 72.2 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit LRR_6 PF13516.1 ETS61162.1 - 0.00099 18.9 0.3 9.4 6.6 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 ETS61162.1 - 0.0031 17.0 3.2 4.2 7.0 0.0 4.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.28 ETS61162.1 - 0.013 15.1 0.1 0.047 13.3 0.1 2.0 1 0 0 1 1 1 0 F-box domain Fibrillarin PF01269.12 ETS61162.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin IU_nuc_hydro PF01156.14 ETS61163.1 - 2.8e-117 391.4 0.0 3.6e-117 391.0 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HSP70 PF00012.15 ETS61164.1 - 1.4e-255 848.8 16.4 1.4e-255 848.8 11.4 2.5 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 ETS61164.1 - 1.3e-16 60.0 0.4 1.7e-15 56.4 0.1 2.6 2 1 0 2 2 2 1 MreB/Mbl protein zf-U1 PF06220.7 ETS61164.1 - 1.5e-07 30.7 0.8 3.1e-07 29.8 0.6 1.5 1 0 0 1 1 1 1 U1 zinc finger Hydantoinase_A PF01968.13 ETS61164.1 - 0.0066 15.5 6.7 0.057 12.5 0.2 3.4 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DUF2680 PF10925.3 ETS61164.1 - 0.55 10.1 4.6 0.64 9.9 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) Ank_4 PF13637.1 ETS61165.1 - 6.9e-14 51.9 0.3 9.4e-07 29.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS61165.1 - 1.9e-11 44.1 0.1 3.6e-09 36.8 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS61165.1 - 3.6e-11 42.9 0.1 3e-08 33.6 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS61165.1 - 5.7e-08 32.1 0.1 2.5e-06 26.9 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 ETS61165.1 - 1.6e-06 27.7 0.1 1.1e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Elf1 PF05129.8 ETS61166.1 - 6e-30 102.7 0.5 6.7e-30 102.6 0.3 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-BED PF02892.10 ETS61166.1 - 0.33 10.7 2.4 6.7 6.5 1.7 2.3 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.1 ETS61166.1 - 0.39 10.6 3.6 1.7 8.6 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 ETS61166.1 - 1.1 8.9 3.8 6.5 6.4 0.3 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Macoilin PF09726.4 ETS61167.1 - 2.8 6.0 15.7 3.2 5.9 10.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 ETS61167.1 - 5.7 6.3 17.9 8.8 5.7 12.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Apt1 PF10351.4 ETS61167.1 - 8.9 5.0 5.8 10 4.8 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SNF2_N PF00176.18 ETS61168.1 - 5.8e-46 156.6 0.0 8.3e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS61168.1 - 4.4e-17 61.6 0.0 4.6e-16 58.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.1 ETS61168.1 - 2.2e-12 46.7 0.0 6.5e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.10 ETS61168.1 - 0.0035 17.1 0.1 0.055 13.2 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RPE65 PF03055.10 ETS61169.1 - 4.4e-135 450.9 0.0 5.2e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein zf-C3HC4 PF00097.20 ETS61170.1 - 5.2e-08 32.4 7.3 1.8e-07 30.7 5.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 ETS61170.1 - 6e-08 32.1 2.7 6e-08 32.1 1.9 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 ETS61170.1 - 1.2e-07 31.4 8.7 1.2e-07 31.4 6.0 2.0 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS61170.1 - 4.2e-06 26.3 6.2 9.2e-06 25.2 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS61170.1 - 2.3e-05 24.0 8.0 5.5e-05 22.8 5.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS61170.1 - 3.6e-05 23.7 8.8 6.5e-05 22.8 5.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS61170.1 - 0.0094 15.8 7.5 0.026 14.3 5.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING LRV_FeS PF05484.6 ETS61170.1 - 0.024 14.1 0.7 0.096 12.2 0.5 2.0 1 0 0 1 1 1 0 LRV protein FeS4 cluster PhnA_Zn_Ribbon PF08274.7 ETS61170.1 - 0.064 13.0 3.7 3.9 7.3 0.1 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_6 PF14835.1 ETS61170.1 - 0.066 12.9 1.8 0.14 11.9 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 ETS61170.1 - 0.069 12.9 1.9 0.16 11.8 1.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PRTP PF01366.13 ETS61170.1 - 0.075 11.0 0.2 0.11 10.4 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein zf-RING_UBOX PF13445.1 ETS61170.1 - 0.091 12.4 4.2 0.2 11.3 2.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 ETS61170.1 - 0.12 12.4 5.8 0.27 11.3 4.0 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_3 PF14369.1 ETS61170.1 - 5.7 7.0 8.6 0.49 10.4 1.8 2.3 2 0 0 2 2 2 0 zinc-finger zf-CCCH_2 PF14608.1 ETS61170.1 - 7.9 6.6 12.9 0.27 11.3 0.4 3.3 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type DCP2 PF05026.8 ETS61171.1 - 6.7e-32 109.2 0.0 1.1e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain DUF427 PF04248.7 ETS61171.1 - 9.1e-28 95.7 0.7 3.3e-27 93.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF427) NUDIX PF00293.23 ETS61171.1 - 1.2e-15 57.3 0.0 2.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Transaldolase PF00923.14 ETS61171.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Transaldolase NGP1NT PF08153.7 ETS61172.1 - 4.5e-42 143.0 0.0 1e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 ETS61172.1 - 5.1e-18 65.1 0.0 7.9e-15 54.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS61172.1 - 1.3e-05 24.5 0.2 4.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 ETS61172.1 - 0.00038 19.7 0.1 0.057 12.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 ETS61172.1 - 0.0026 16.9 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 ETS61172.1 - 0.0033 16.8 0.1 0.62 9.4 0.0 3.0 1 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETS61172.1 - 0.23 11.2 8.6 0.38 10.5 0.0 4.0 4 1 1 5 5 5 0 Dynamin family SIR2 PF02146.12 ETS61173.1 - 8.5e-57 191.7 0.0 1.6e-56 190.8 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 ETS61173.1 - 2.1e-09 37.1 0.3 1.2e-05 24.9 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF592) SURF2 PF05477.6 ETS61173.1 - 0.011 14.9 1.0 0.026 13.6 0.7 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CutC PF03932.9 ETS61173.1 - 0.017 14.4 0.0 0.046 12.9 0.0 1.6 2 0 0 2 2 2 0 CutC family DUF1323 PF07037.6 ETS61173.1 - 0.042 14.0 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) TPPII_N PF12583.3 ETS61173.1 - 1.1 9.4 6.6 2.4 8.2 4.5 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal ADK PF00406.17 ETS61174.1 - 3e-05 23.9 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 ETS61174.1 - 0.00069 20.4 0.8 0.0021 18.8 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS61174.1 - 0.027 14.3 0.0 0.093 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETS61174.1 - 0.069 13.1 1.6 1.6 8.6 0.2 2.9 1 1 2 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 ETS61174.1 - 0.078 12.8 0.3 1.9 8.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS61174.1 - 0.081 13.2 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 ETS61174.1 - 0.091 13.0 2.2 0.15 12.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain Cys_Met_Meta_PP PF01053.15 ETS61175.1 - 1.6e-138 461.1 0.0 3.7e-138 460.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETS61175.1 - 0.016 14.2 0.1 0.04 12.9 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DHH PF01368.15 ETS61177.1 - 4.2e-08 32.9 0.0 1.2e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 DHH family Ribonuc_2-5A PF06479.7 ETS61177.1 - 0.0085 15.9 2.8 0.53 10.1 0.2 2.5 2 1 0 2 2 2 2 Ribonuclease 2-5A DHHA2 PF02833.9 ETS61177.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.4 1 1 0 1 1 1 0 DHHA2 domain SNARE_assoc PF09335.6 ETS61178.1 - 6.4e-30 103.8 6.7 2.9e-29 101.7 4.6 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein SHMT PF00464.14 ETS61179.1 - 4.7e-176 585.0 0.0 5.7e-176 584.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 ETS61179.1 - 0.00077 18.6 0.0 0.0026 16.9 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cyt-b5 PF00173.23 ETS61180.1 - 2.4e-14 52.8 0.0 4.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 ETS61180.1 - 1.6e-13 50.7 26.7 1.6e-13 50.7 18.5 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lactamase_B PF00753.22 ETS61180.1 - 0.0057 16.3 0.3 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RGS PF00615.14 ETS61181.1 - 6.7e-13 48.7 0.0 2.4e-07 30.8 0.0 2.4 2 1 0 2 2 2 2 Regulator of G protein signaling domain Pkinase PF00069.20 ETS61182.1 - 3.4e-52 177.1 0.0 2.9e-48 164.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61182.1 - 4e-21 75.2 0.0 3.6e-18 65.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 ETS61182.1 - 0.0024 17.6 0.8 0.01 15.5 0.5 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS61182.1 - 0.0028 16.6 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS61182.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kin17_mid PF10357.4 ETS61183.1 - 2.6e-48 162.8 0.3 4.7e-48 162.0 0.2 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 ETS61183.1 - 3.5e-06 26.9 2.4 6.9e-06 26.0 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS61183.1 - 2.2e-05 24.4 1.7 4.5e-05 23.4 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETS61183.1 - 0.0085 16.1 0.7 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 ETS61183.1 - 0.01 15.6 0.7 0.037 13.8 0.5 2.0 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 ETS61183.1 - 0.12 12.7 1.7 0.29 11.5 1.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Spc97_Spc98 PF04130.8 ETS61184.1 - 6.8e-118 394.3 0.0 1.2e-117 393.5 0.0 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family RasGAP PF00616.14 ETS61185.1 - 9.8e-56 188.5 0.8 2.7e-55 187.1 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 ETS61185.1 - 3.3e-41 140.2 0.4 3.3e-41 140.2 0.3 2.0 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 ETS61185.1 - 0.0019 18.5 2.4 0.25 11.6 0.1 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF972) KxDL PF10241.4 ETS61185.1 - 0.81 9.6 6.3 2.4 8.0 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized conserved protein Myb_DNA-bind_6 PF13921.1 ETS61186.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4128 PF13554.1 ETS61186.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function DUF619 PF04768.8 ETS61187.1 - 1.9e-46 157.6 0.0 3.5e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 ETS61187.1 - 1.8e-25 89.6 0.0 5.3e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 ETS61187.1 - 9.2e-21 74.4 0.0 2.5e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Amino acid kinase family HLH PF00010.21 ETS61187.1 - 1.2e-08 34.4 0.1 2.9e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DapB_N PF01113.15 ETS61187.1 - 0.038 13.9 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SOXp PF12336.3 ETS61187.1 - 7.6 7.2 10.6 24 5.5 0.0 2.7 2 0 0 2 2 2 0 SOX transcription factor Ribosomal_L24e PF01246.15 ETS61189.1 - 1.4e-24 85.7 2.3 2.9e-21 75.1 0.5 2.7 2 0 0 2 2 2 2 Ribosomal protein L24e Aminotran_1_2 PF00155.16 ETS61190.1 - 7.8e-53 179.7 0.0 1.7e-49 168.6 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS61190.1 - 0.00023 20.3 0.0 0.00043 19.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 ETS61190.1 - 0.01 14.4 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 ETS61190.1 - 0.071 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SAMP PF05924.6 ETS61190.1 - 0.1 11.7 1.4 0.16 11.1 0.1 2.1 2 0 0 2 2 2 0 SAMP Motif LSM PF01423.17 ETS61192.1 - 5.3e-18 64.3 0.3 6.2e-18 64.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 ETS61192.1 - 2.8e-06 27.1 0.1 3.3e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 ETS61192.1 - 0.017 14.8 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Velvet PF11754.3 ETS61193.1 - 7.2e-49 166.1 0.5 6.5e-34 117.3 0.0 2.5 2 0 0 2 2 2 2 Velvet factor GCD14 PF08704.5 ETS61194.1 - 5.1e-81 271.8 2.7 7.5e-45 153.3 0.3 3.2 2 1 1 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 ETS61194.1 - 0.019 15.0 0.0 0.046 13.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.9 ETS61194.1 - 0.072 12.3 0.2 4.8 6.3 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 Radical_SAM PF04055.16 ETS61194.1 - 0.1 12.8 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily GATA PF00320.22 ETS61195.1 - 2.1e-13 49.3 6.3 5.8e-13 47.9 4.3 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 ETS61195.1 - 0.0061 16.5 0.1 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 ETS61195.1 - 0.24 11.5 0.0 0.52 10.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold Kinesin PF00225.18 ETS61196.1 - 4.5e-111 370.7 0.0 9.4e-111 369.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3450 PF11932.3 ETS61196.1 - 0.0025 17.1 2.6 0.0025 17.1 1.8 5.2 3 1 2 5 5 5 1 Protein of unknown function (DUF3450) Drf_GBD PF06371.8 ETS61197.1 - 4.2e-10 39.3 0.0 2.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Rcd1 PF04078.8 ETS61197.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Peptidase_M41 PF01434.13 ETS61198.1 - 3.2e-72 242.4 0.5 5.6e-72 241.6 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 ETS61198.1 - 1.3e-42 145.1 0.0 3.1e-42 143.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 ETS61198.1 - 4.1e-10 39.7 0.2 1.9e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 ETS61198.1 - 0.00038 20.5 0.0 0.055 13.6 0.0 2.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 ETS61198.1 - 0.0039 15.9 0.0 0.0062 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 ETS61198.1 - 0.013 15.2 0.0 0.061 13.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS61198.1 - 0.014 16.2 0.0 0.051 14.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS61198.1 - 0.015 15.0 0.5 0.015 15.0 0.3 2.8 3 0 0 3 3 3 0 Part of AAA domain AAA_2 PF07724.9 ETS61198.1 - 0.015 15.1 0.2 0.07 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 ETS61198.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETS61198.1 - 0.019 14.9 0.2 0.15 12.0 0.1 2.3 1 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 ETS61198.1 - 0.039 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 ETS61198.1 - 0.079 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS61198.1 - 0.1 11.9 0.5 0.32 10.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain Mo25 PF08569.6 ETS61199.1 - 1.8e-127 425.0 1.1 3.1e-127 424.2 0.8 1.3 1 1 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 ETS61199.1 - 0.047 13.9 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats DUF544 PF04424.8 ETS61199.1 - 0.097 12.4 0.5 2.9 7.7 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF544) GP40 PF11025.3 ETS61199.1 - 0.29 10.7 2.7 0.52 9.8 1.9 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Period_C PF12114.3 ETS61199.1 - 2 7.9 7.0 3.7 7.0 4.8 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.4 ETS61199.1 - 5.3 6.4 9.0 7.9 5.8 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 ETS61199.1 - 5.7 6.9 12.8 11 6.0 8.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Methyltransf_15 PF09445.5 ETS61200.1 - 7.9e-34 116.5 0.0 1.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 ETS61200.1 - 7.8e-09 35.5 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 ETS61200.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 ETS61200.1 - 0.00046 20.7 0.0 0.00084 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETS61200.1 - 0.00075 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 ETS61200.1 - 0.0035 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 ETS61200.1 - 0.017 14.2 0.1 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 ETS61200.1 - 0.02 14.3 0.0 0.072 12.4 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 ETS61200.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Abhydrolase_3 PF07859.8 ETS61201.1 - 6.9e-19 68.2 0.0 4.1e-17 62.4 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS61201.1 - 3e-10 39.2 0.0 1.2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 ETS61201.1 - 0.024 14.8 1.1 0.048 13.8 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain UCH PF00443.24 ETS61202.1 - 2e-49 168.1 0.0 3.5e-49 167.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS61202.1 - 1.3e-19 70.7 0.0 1.1e-13 51.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 ETS61202.1 - 7.2e-12 45.2 2.3 7.2e-12 45.2 1.6 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein HSP70 PF00012.15 ETS61203.1 - 4e-62 209.9 4.9 8.4e-56 189.1 0.0 2.9 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 ETS61203.1 - 0.0027 16.3 0.2 0.007 14.9 0.1 1.6 1 0 0 1 1 1 1 MreB/Mbl protein Ras PF00071.17 ETS61204.1 - 2.5e-54 183.0 0.1 3.4e-54 182.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS61204.1 - 6.6e-17 62.1 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61204.1 - 3.3e-13 49.2 0.0 9.4e-13 47.7 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS61204.1 - 0.00013 21.2 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS61204.1 - 0.0024 17.3 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CBFD_NFYB_HMF PF00808.18 ETS61205.1 - 3.7e-15 55.7 0.8 3.7e-15 55.7 0.5 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS61205.1 - 2.1e-07 30.9 0.3 2.9e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PCI PF01399.22 ETS61206.1 - 6.9e-05 23.1 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain Apc3 PF12895.2 ETS61206.1 - 0.00081 19.4 2.0 0.0073 16.4 1.5 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 ETS61206.1 - 0.089 12.7 4.8 0.57 10.2 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS61206.1 - 0.14 12.8 6.9 5.4 7.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS61206.1 - 0.22 11.4 8.6 0.27 11.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS61206.1 - 0.28 11.7 3.9 10 6.8 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3317 PF11779.3 ETS61207.1 - 4.4e-15 54.8 4.1 6.7e-15 54.2 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Caa3_CtaG PF09678.5 ETS61207.1 - 0.00066 18.6 1.7 0.00088 18.2 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) AF-4 PF05110.8 ETS61207.1 - 9 4.0 12.6 11 3.7 8.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein G-patch PF01585.18 ETS61208.1 - 7.3e-13 48.0 0.9 3.4e-12 45.9 0.4 2.4 2 0 0 2 2 2 1 G-patch domain R3H PF01424.17 ETS61208.1 - 5.8e-10 38.7 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 ETS61208.1 - 0.00014 21.6 0.6 0.00014 21.6 0.4 3.2 3 0 0 3 3 3 1 DExH-box splicing factor binding site AAA_22 PF13401.1 ETS61208.1 - 0.14 12.3 0.8 0.76 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain EF-hand_1 PF00036.27 ETS61209.1 - 2.1e-26 89.1 18.1 2.1e-09 35.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETS61209.1 - 1.7e-25 88.9 13.1 6.5e-13 48.6 2.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETS61209.1 - 3.6e-25 85.5 14.3 1.2e-08 34.1 0.1 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETS61209.1 - 8.3e-18 63.7 17.2 2.1e-11 43.2 1.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 ETS61209.1 - 1.4e-16 58.9 15.7 5.4e-06 25.5 0.1 4.1 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 ETS61209.1 - 7.9e-11 41.7 1.1 0.00017 21.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETS61209.1 - 5.6e-08 32.4 3.4 0.00081 19.0 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 ETS61209.1 - 0.01 15.4 0.3 0.18 11.3 0.0 2.6 1 1 1 3 3 3 0 Caleosin related protein DUF1636 PF07845.6 ETS61209.1 - 0.034 14.3 0.0 1 9.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1636) LTXXQ PF07813.7 ETS61209.1 - 0.06 13.8 1.0 0.63 10.5 0.1 2.3 2 1 0 2 2 2 0 LTXXQ motif family protein SPARC_Ca_bdg PF10591.4 ETS61209.1 - 0.18 11.8 4.2 2.2 8.3 0.4 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.1 ETS61209.1 - 1.7 9.0 4.4 3.2 8.1 0.5 2.3 1 1 1 2 2 2 0 Toprim-like DEAD PF00270.24 ETS61210.1 - 1.5e-19 70.1 0.0 9.2e-19 67.5 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS61210.1 - 6.5e-19 67.5 0.0 2e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS61210.1 - 9e-19 68.0 0.0 2.5e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS61210.1 - 0.0035 16.2 0.0 0.0062 15.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain 60KD_IMP PF02096.15 ETS61211.1 - 2.7e-16 59.8 0.0 8.4e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein HJURP_C PF12347.3 ETS61211.1 - 0.059 12.9 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat IGR PF09597.5 ETS61212.1 - 3.7e-11 42.7 0.2 7.8e-11 41.7 0.2 1.6 1 1 0 1 1 1 1 IGR protein motif Glyoxal_oxid_N PF07250.6 ETS61213.1 - 1.1e-46 158.9 0.0 5.7e-45 153.2 0.0 2.9 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 ETS61213.1 - 3.6e-26 91.1 0.1 6.9e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Tfb4 PF03850.9 ETS61214.1 - 1.4e-70 237.6 6.7 4.9e-69 232.6 4.6 2.2 1 1 0 1 1 1 1 Transcription factor Tfb4 DEAD PF00270.24 ETS61215.1 - 5.2e-36 123.6 0.0 3e-35 121.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS61215.1 - 1.7e-20 72.6 0.0 4.9e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS61215.1 - 3e-08 33.7 0.0 9.6e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETS61215.1 - 0.0007 19.2 0.4 0.0026 17.4 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS61215.1 - 0.0048 17.0 0.8 0.11 12.6 0.5 2.7 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.6 ETS61217.1 - 2.7e-21 75.3 0.1 1e-20 73.4 0.0 2.0 2 1 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.10 ETS61217.1 - 0.00047 18.9 0.1 0.0079 14.9 0.0 2.3 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 ETS61217.1 - 0.00077 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 ETS61217.1 - 0.0025 17.9 0.5 0.01 15.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS61217.1 - 0.0038 17.2 0.4 0.075 13.0 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 ETS61217.1 - 0.004 16.6 0.0 0.01 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA PF00004.24 ETS61217.1 - 0.0095 16.1 0.3 0.034 14.3 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 ETS61217.1 - 0.01 15.8 0.1 0.56 10.2 0.1 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Rpr2 PF04032.11 ETS61217.1 - 0.047 13.5 0.3 0.17 11.7 0.2 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RuvB_N PF05496.7 ETS61217.1 - 0.051 12.6 0.1 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 ETS61217.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 ETS61217.1 - 0.092 12.3 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETS61217.1 - 0.098 12.3 0.1 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTP_transf_2 PF01909.18 ETS61218.1 - 1.4e-05 25.3 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 ETS61218.1 - 6.3e-05 22.8 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Rrn6 PF10214.4 ETS61218.1 - 0.0067 14.5 1.4 0.015 13.4 1.0 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor BEX PF04538.7 ETS61218.1 - 6.3 7.0 12.8 0.035 14.3 1.3 2.6 2 1 0 2 2 2 0 Brain expressed X-linked like family SUZ PF12752.2 ETS61219.1 - 1.1e-11 45.1 0.6 1.1e-11 45.1 0.4 2.3 2 1 0 2 2 2 1 SUZ domain MRP-L28 PF09812.4 ETS61219.1 - 0.028 14.2 0.2 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Exonuc_VIII PF06630.6 ETS61219.1 - 0.048 12.9 1.6 0.076 12.3 1.1 1.4 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Mito_carr PF00153.22 ETS61221.1 - 4e-65 215.5 4.8 7.1e-23 80.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Macoilin PF09726.4 ETS61222.1 - 3.1 5.9 13.0 5.1 5.2 9.0 1.4 1 1 0 1 1 1 0 Transmembrane protein DUF4140 PF13600.1 ETS61222.1 - 5.9 7.4 15.5 0.17 12.3 4.3 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GTP_EFTU PF00009.22 ETS61223.1 - 1.6e-54 184.2 0.1 2.5e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS61223.1 - 3.5e-36 123.3 0.0 7.9e-36 122.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS61223.1 - 4.9e-15 55.4 1.7 4.9e-15 55.4 1.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ETS61223.1 - 0.0017 17.9 0.4 0.0046 16.5 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 ETS61223.1 - 0.003 17.4 0.3 0.011 15.7 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TAFII55_N PF04658.8 ETS61224.1 - 3.1e-53 179.5 0.1 3.1e-53 179.5 0.0 1.6 2 0 0 2 2 2 1 TAFII55 protein conserved region Ribosomal_L32e PF01655.13 ETS61225.1 - 8.1e-48 161.0 2.8 9.6e-48 160.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L13 PF00572.13 ETS61226.1 - 1.8e-25 89.4 0.0 3.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 FRG1 PF06229.7 ETS61227.1 - 6.5e-20 71.3 3.1 6.6e-18 64.8 2.1 3.2 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 ETS61227.1 - 1.4e-05 25.1 0.0 4.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Fascin domain SPT2 PF08243.6 ETS61227.1 - 4.9 7.5 8.1 0.81 10.0 1.6 2.4 3 0 0 3 3 3 0 SPT2 chromatin protein DUF4504 PF14953.1 ETS61228.1 - 7.5e-13 48.3 1.6 8.8e-06 25.2 0.3 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) ubiquitin PF00240.18 ETS61231.1 - 2.9e-19 68.2 0.2 4.8e-19 67.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETS61231.1 - 2.8e-09 36.5 0.3 4.2e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 ETS61231.1 - 9.8e-07 28.4 0.3 3.3e-06 26.7 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.4 ETS61231.1 - 4.2e-06 26.8 0.0 6.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETS61231.1 - 0.00074 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETS61231.1 - 0.036 14.3 0.1 0.088 13.0 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DUF726 PF05277.7 ETS61232.1 - 1.5e-53 181.8 0.8 2.4e-53 181.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 ETS61232.1 - 3.2e-05 23.9 0.1 9.6e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS61232.1 - 0.00017 21.3 0.4 0.00051 19.8 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.6 ETS61232.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.20 ETS61232.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Meth_synt_2 PF01717.13 ETS61233.1 - 4.6e-146 485.9 0.0 2.4e-136 453.9 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS61233.1 - 4.6e-124 413.7 0.0 1.9e-111 372.2 0.1 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 ETS61233.1 - 0.0023 16.9 0.1 0.071 12.0 0.0 2.7 3 0 0 3 3 3 1 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.4 ETS61233.1 - 0.035 13.5 0.5 0.088 12.3 0.4 1.7 1 0 0 1 1 1 0 Short C-terminal domain RabGAP-TBC PF00566.13 ETS61234.1 - 1.2e-49 168.7 0.0 2e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 ETS61234.1 - 1.4e-06 27.6 0.0 3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Metallophos PF00149.23 ETS61235.1 - 2.2e-41 141.4 0.7 3.3e-41 140.8 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DEPP PF15343.1 ETS61236.1 - 0.042 13.4 0.1 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Decidual protein induced by progesterone family DUF2360 PF10152.4 ETS61236.1 - 0.082 13.1 2.8 0.11 12.8 2.0 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Totivirus_coat PF05518.6 ETS61236.1 - 2.9 5.5 7.3 3.4 5.3 5.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein Glyco_hydro_16 PF00722.16 ETS61237.1 - 3.8e-37 127.3 2.5 1.1e-36 125.8 1.7 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3712 PF12505.3 ETS61240.1 - 6.7e-101 333.0 44.8 9.4e-22 77.3 0.0 9.3 9 1 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 ETS61240.1 - 2e-07 31.3 15.1 3 8.2 0.0 8.0 7 0 0 7 7 7 5 Late embryogenesis abundant protein HTH_10 PF04967.7 ETS61241.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain AATase PF07247.7 ETS61242.1 - 0.079 11.4 0.0 4.2 5.7 0.0 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase Condensation PF00668.15 ETS61242.1 - 0.099 11.4 0.2 6.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Condensation domain Proteasome PF00227.21 ETS61243.1 - 2.7e-33 114.8 0.0 5.5e-33 113.8 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit MamL-1 PF09596.5 ETS61243.1 - 0.14 11.9 0.5 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 MamL-1 domain Cullin PF00888.17 ETS61244.1 - 7.8e-31 107.2 0.0 1.2e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family RNase_PH PF01138.16 ETS61245.1 - 1.4e-31 109.5 0.0 2.2e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETS61245.1 - 0.00057 19.7 0.0 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 AMP-binding PF00501.23 ETS61246.1 - 4.9e-81 272.2 0.0 8.2e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS61246.1 - 1.1e-06 29.4 0.6 2.7e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NolV PF06635.7 ETS61248.1 - 0.086 11.9 0.4 0.085 12.0 0.3 1.1 1 0 0 1 1 1 0 Nodulation protein NolV Metallophos PF00149.23 ETS61249.1 - 1.8e-07 30.7 5.3 4.2e-07 29.5 3.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HGTP_anticodon2 PF12745.2 ETS61249.1 - 0.12 11.4 4.0 0.19 10.8 2.8 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs UAA PF08449.6 ETS61251.1 - 1.4e-75 254.0 4.1 3.7e-75 252.6 2.8 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 ETS61251.1 - 0.014 14.5 1.0 0.046 12.8 0.7 1.7 1 1 0 1 1 1 0 Nucleotide-sugar transporter TPT PF03151.11 ETS61251.1 - 0.42 10.2 10.4 0.097 12.3 2.3 2.7 2 0 0 2 2 2 0 Triose-phosphate Transporter family SURF1 PF02104.10 ETS61252.1 - 3.9e-47 160.8 0.0 8.1e-47 159.7 0.0 1.5 1 1 0 1 1 1 1 SURF1 family YTH PF04146.10 ETS61255.1 - 2.6e-48 163.1 0.0 5.9e-48 162.0 0.0 1.6 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 ETS61255.1 - 0.00058 19.4 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS61255.1 - 0.044 13.6 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS61255.1 - 0.24 11.4 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4106 PF13388.1 ETS61255.1 - 2 7.2 6.7 4.5 6.1 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Dus PF01207.12 ETS61256.1 - 1.3e-70 237.7 0.0 2.8e-70 236.6 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) adh_short PF00106.20 ETS61257.1 - 2.2e-12 47.2 0.2 4.6e-12 46.1 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS61257.1 - 2.8e-05 23.8 0.1 5.2e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS61257.1 - 0.011 15.7 0.0 6.1 6.8 0.0 2.3 1 1 0 2 2 2 0 NADH(P)-binding adh_short_C2 PF13561.1 ETS61257.1 - 0.052 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Bromodomain PF00439.20 ETS61258.1 - 5.2e-21 74.3 0.0 9.5e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain PRMT5 PF05185.11 ETS61259.1 - 5e-10 38.8 0.0 9e-09 34.7 0.0 2.2 2 1 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 ETS61259.1 - 1.7e-05 25.3 0.1 0.00011 22.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS61259.1 - 8.6e-05 22.5 0.2 0.049 13.6 0.2 2.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS61259.1 - 0.00011 21.4 0.1 0.00022 20.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 ETS61259.1 - 0.0018 18.0 0.0 0.0034 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 ETS61259.1 - 0.0057 16.6 0.1 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase FkbM domain MTS PF05175.9 ETS61259.1 - 0.011 15.1 0.8 0.02 14.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_9 PF08003.6 ETS61259.1 - 0.015 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.1 ETS61259.1 - 0.018 14.6 0.0 0.13 11.8 0.0 2.4 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_32 PF13679.1 ETS61259.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 ETS61259.1 - 0.038 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_11 PF08241.7 ETS61259.1 - 0.045 14.2 0.1 1.3 9.6 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain RrnaAD PF00398.15 ETS61259.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cellulase PF00150.13 ETS61260.1 - 5.5e-12 45.4 9.3 2.8e-11 43.1 6.4 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AA_kinase PF00696.23 ETS61263.1 - 3.2e-37 128.3 0.4 1.6e-31 109.6 0.0 2.2 1 1 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 ETS61263.1 - 7.9e-12 44.4 0.1 1.6e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 ETS61263.1 - 4.1e-10 39.0 1.3 3.2e-07 29.7 0.1 2.6 2 0 0 2 2 2 2 ACT domain Ecl1 PF12855.2 ETS61264.1 - 5.2e-05 22.4 0.1 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 Life-span regulatory factor NicO PF03824.11 ETS61264.1 - 6.3 6.0 20.3 16 4.6 14.1 1.6 1 0 0 1 1 1 0 High-affinity nickel-transport protein RNA_lig_T4_1 PF09511.5 ETS61265.1 - 2.4e-73 246.2 0.0 3.5e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 ETS61265.1 - 1.6e-19 70.4 0.0 3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 ETS61265.1 - 1e-14 54.4 0.0 2.1e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.1 ETS61265.1 - 0.00011 22.0 0.1 0.00044 20.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS61265.1 - 0.0039 17.9 0.0 0.013 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETS61265.1 - 0.047 13.9 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prefoldin_2 PF01920.15 ETS61266.1 - 1.4e-22 79.4 15.2 1.6e-22 79.2 10.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 ETS61266.1 - 0.00096 18.8 7.2 0.0013 18.5 5.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Snf7 PF03357.16 ETS61266.1 - 0.0059 16.0 5.0 0.0059 16.0 3.5 2.0 2 0 0 2 2 2 1 Snf7 IncA PF04156.9 ETS61266.1 - 0.0081 15.7 9.2 0.0098 15.4 6.4 1.1 1 0 0 1 1 1 1 IncA protein Nckap1 PF09735.4 ETS61266.1 - 0.013 13.0 1.9 0.013 12.9 1.3 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Atg14 PF10186.4 ETS61266.1 - 0.056 12.3 8.7 0.066 12.1 6.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4349 PF14257.1 ETS61266.1 - 0.059 12.5 5.6 0.074 12.2 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1192 PF06698.6 ETS61266.1 - 0.065 13.0 0.7 0.065 13.0 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) STAT_alpha PF01017.15 ETS61266.1 - 0.068 12.8 6.1 0.11 12.1 0.3 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain TSC22 PF01166.13 ETS61266.1 - 0.081 12.9 2.5 0.6 10.1 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family BTAD PF03704.12 ETS61266.1 - 0.087 13.1 0.3 0.087 13.1 0.2 1.6 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Occludin_ELL PF07303.8 ETS61266.1 - 0.092 13.4 8.4 0.26 12.0 1.9 2.1 1 1 1 2 2 2 0 Occludin homology domain APG6 PF04111.7 ETS61266.1 - 0.093 11.7 8.3 0.13 11.3 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Hemagglutinin PF00509.13 ETS61266.1 - 0.12 10.4 2.5 0.1 10.7 1.0 1.4 1 1 0 1 1 1 0 Haemagglutinin Prefoldin PF02996.12 ETS61266.1 - 0.27 10.8 13.4 0.063 12.9 3.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 ETS61266.1 - 0.38 10.7 11.9 0.53 10.3 8.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TcdA_TcdB PF12919.2 ETS61266.1 - 0.39 9.1 6.0 0.49 8.8 4.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Fib_alpha PF08702.5 ETS61266.1 - 0.57 10.3 9.8 2.6 8.1 7.0 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 ETS61266.1 - 0.6 9.9 15.6 0.34 10.7 2.9 2.1 1 1 1 2 2 2 0 Tropomyosin like Macoilin PF09726.4 ETS61266.1 - 0.68 8.1 10.2 0.77 7.9 7.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Rootletin PF15035.1 ETS61266.1 - 0.77 9.7 7.7 0.25 11.3 2.9 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 ETS61266.1 - 1.1 9.1 11.6 0.71 9.7 2.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.7 ETS61266.1 - 1.2 8.9 10.8 0.86 9.3 3.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 ETS61266.1 - 1.2 9.5 10.6 1.5 9.2 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMPIT PF07851.8 ETS61266.1 - 1.5 7.8 7.0 1.8 7.5 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein FemAB PF02388.11 ETS61266.1 - 1.8 7.1 8.8 2.4 6.7 1.9 2.0 2 0 0 2 2 2 0 FemAB family DivIC PF04977.10 ETS61266.1 - 2.3 7.7 13.7 3.4 7.2 2.9 2.4 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 ETS61266.1 - 2.6 7.9 11.5 0.26 11.1 2.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.6 ETS61266.1 - 4.1 7.4 13.5 0.12 12.3 1.1 2.4 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase Snapin_Pallidin PF14712.1 ETS61266.1 - 4.9 7.5 9.1 18 5.6 5.5 2.2 1 1 1 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.7 ETS61266.1 - 5.3 7.3 9.5 1.9 8.8 2.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 ETS61266.1 - 5.6 5.2 13.0 9.3 4.5 9.0 1.2 1 1 0 1 1 1 0 AAA domain ISG65-75 PF11727.3 ETS61266.1 - 6.7 5.6 10.2 2.3 7.1 3.3 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein DNA_pol_A_exo1 PF01612.15 ETS61267.1 - 1.2e-17 63.9 0.0 2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Ribosomal_S17e PF00833.13 ETS61268.1 - 2.8e-56 188.5 0.0 5e-56 187.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.14 ETS61269.1 - 6.1e-24 84.3 0.0 8.3e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_hydro_8 PF01270.12 ETS61270.1 - 1.4e-37 129.2 0.0 1.6e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 tRNA-synt_2b PF00587.20 ETS61271.1 - 1e-35 122.8 0.6 1.5e-35 122.2 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 ETS61271.1 - 1.3e-20 73.3 9.3 1.3e-20 73.3 6.4 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain NuA4 PF09340.5 ETS61271.1 - 0.0032 17.0 0.1 0.0087 15.6 0.0 1.8 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 tRNA-synt_His PF13393.1 ETS61271.1 - 0.031 13.3 1.0 0.17 10.8 0.0 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase YPEB PF14620.1 ETS61271.1 - 0.048 12.6 3.4 0.08 11.9 1.8 1.7 2 0 0 2 2 2 0 YpeB sporulation PEP-utilisers_N PF05524.8 ETS61271.1 - 0.058 13.1 0.7 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Mod_r PF07200.8 ETS61271.1 - 0.087 12.7 4.2 0.21 11.5 2.9 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FlxA PF14282.1 ETS61271.1 - 2.4 8.1 6.9 0.94 9.4 2.8 1.8 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 ETS61271.1 - 5.6 6.5 6.5 1.8 8.0 2.0 1.9 2 0 0 2 2 2 0 IncA protein DnaJ PF00226.26 ETS61272.1 - 1.6e-19 69.3 0.1 1.6e-19 69.3 0.0 2.6 2 1 0 2 2 2 1 DnaJ domain Ribosomal_L44 PF00935.14 ETS61273.1 - 5.9e-33 112.7 9.7 1.2e-32 111.7 6.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Ad_cyc_g-alpha PF08509.6 ETS61273.1 - 0.096 12.0 0.4 0.22 10.8 0.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain Ribosomal_L14e PF01929.12 ETS61274.1 - 4.7e-28 97.3 0.5 6.2e-28 96.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 ETS61274.1 - 0.00017 21.1 0.4 0.00028 20.4 0.3 1.3 1 0 0 1 1 1 1 KOW motif UCH PF00443.24 ETS61275.1 - 5.6e-40 137.1 0.0 2.4e-35 121.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS61275.1 - 0.043 13.2 0.0 22 4.3 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase CTP_transf_1 PF01148.15 ETS61276.1 - 0.19 11.3 4.8 0.25 10.9 3.3 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family THOC7 PF05615.8 ETS61277.1 - 9.2e-23 81.0 9.1 9.2e-23 81.0 6.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 DUF2853 PF11015.3 ETS61277.1 - 0.00038 20.8 0.9 0.033 14.6 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2853) CENP-F_leu_zip PF10473.4 ETS61277.1 - 0.00059 19.6 7.6 0.00059 19.6 5.3 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.10 ETS61277.1 - 0.0045 16.6 5.1 0.0045 16.6 3.6 1.6 1 1 0 1 1 1 1 Mnd1 family DUF1664 PF07889.7 ETS61277.1 - 0.0072 16.1 4.5 0.021 14.6 1.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Arfaptin PF06456.8 ETS61277.1 - 0.016 14.5 1.1 0.016 14.5 0.8 2.0 1 1 0 2 2 2 0 Arfaptin-like domain APG6 PF04111.7 ETS61277.1 - 0.12 11.3 8.1 0.22 10.5 5.2 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF2408 PF10303.4 ETS61277.1 - 0.25 11.4 5.2 0.26 11.4 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) FUSC PF04632.7 ETS61277.1 - 0.26 9.6 9.4 0.45 8.8 6.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.8 ETS61277.1 - 1.3 8.4 5.4 1.2 8.5 1.3 2.0 1 1 0 2 2 2 0 fzo-like conserved region Snapin_Pallidin PF14712.1 ETS61277.1 - 1.3 9.3 6.5 2 8.7 1.9 2.5 1 1 2 3 3 3 0 Snapin/Pallidin Kinetocho_Slk19 PF12709.2 ETS61277.1 - 1.4 9.0 6.8 1.7 8.8 1.1 2.8 2 1 1 3 3 3 0 Central kinetochore-associated Spc24 PF08286.6 ETS61277.1 - 1.8 8.2 5.0 2.6 7.7 1.3 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 ETS61277.1 - 3.4 7.2 9.1 6.4 6.3 1.8 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 ETS61277.1 - 6.8 7.0 6.7 9.8 6.5 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TBPIP PF07106.8 ETS61277.1 - 7 6.1 9.3 5.9 6.4 2.2 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SKN1 PF03935.10 ETS61278.1 - 1.2e-202 673.5 1.3 1.5e-202 673.2 0.9 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-CCHC PF00098.18 ETS61279.1 - 1.3e-39 132.2 47.1 1.3e-08 34.3 1.0 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 ETS61279.1 - 9.3e-08 31.6 29.1 0.44 10.3 0.1 6.1 4 2 2 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.1 ETS61279.1 - 3.4e-07 29.6 29.2 0.012 15.0 0.3 6.2 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 ETS61279.1 - 1.4e-05 24.6 37.2 0.2 11.3 0.3 5.9 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 ETS61279.1 - 0.057 13.0 2.3 0.057 13.0 1.6 6.3 4 3 2 6 6 6 0 Zinc knuckle zf-TRAF PF02176.13 ETS61279.1 - 7.7 6.9 16.6 5.6 7.4 1.9 4.7 3 2 1 4 4 4 0 TRAF-type zinc finger ProRS-C_1 PF09180.6 ETS61280.1 - 2.5e-23 81.7 1.7 5.8e-23 80.6 1.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 ETS61280.1 - 8.5e-23 80.8 0.1 3.3e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS61280.1 - 3.2e-20 71.8 0.0 9.7e-20 70.3 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 ETS61280.1 - 1.9e-17 63.2 0.4 3.8e-17 62.2 0.3 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Fer2 PF00111.22 ETS61281.1 - 2.4e-11 43.1 0.2 3.5e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain adh_short_C2 PF13561.1 ETS61282.1 - 1.2e-24 87.4 0.1 1.7e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS61282.1 - 2.8e-23 82.6 0.7 4.6e-23 81.9 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS61282.1 - 1.3e-10 41.2 0.3 2.4e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 KR domain Glyco_hydro_2_N PF02837.13 ETS61283.1 - 6.6e-24 84.3 1.2 1.1e-23 83.6 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 ETS61283.1 - 7.5e-17 61.1 0.0 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 ETS61283.1 - 5e-07 30.1 0.0 1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 ETS61283.1 - 0.013 15.7 0.1 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain DUF3422 PF11902.3 ETS61284.1 - 0.0081 15.0 5.5 0.0081 15.0 3.8 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3422) MtrG PF04210.8 ETS61284.1 - 0.063 12.9 0.7 1.4 8.6 0.1 2.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G L27 PF02828.11 ETS61284.1 - 0.066 12.9 0.6 0.35 10.5 0.0 2.4 2 0 0 2 2 2 0 L27 domain DUF3461 PF11944.3 ETS61284.1 - 0.13 12.1 7.1 0.22 11.3 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) Prominin PF05478.6 ETS61284.1 - 0.29 8.5 4.6 0.51 7.8 3.2 1.4 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.7 ETS61284.1 - 1 9.6 13.2 5.5 7.3 2.4 4.2 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 ETS61284.1 - 1.7 7.5 34.2 1.1 8.1 4.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 ETS61284.1 - 2.1 8.2 5.3 63 3.5 0.2 3.9 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0184 PF03670.8 ETS61284.1 - 6.5 7.0 11.7 40 4.4 3.6 4.5 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) HALZ PF02183.13 ETS61284.1 - 7.7 6.3 13.8 3 7.6 0.2 4.8 4 1 1 5 5 5 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 ETS61284.1 - 7.7 6.3 10.1 37 4.1 2.6 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_14 PF03647.8 ETS61285.1 - 2.2e-21 76.0 5.4 2.5e-21 75.8 3.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C ASFV_J13L PF05568.6 ETS61286.1 - 0.011 15.2 0.1 0.038 13.5 0.0 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein SKG6 PF08693.5 ETS61286.1 - 0.02 14.2 0.2 0.053 12.8 0.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 ETS61286.1 - 0.027 14.1 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain VCBS PF13517.1 ETS61286.1 - 0.033 14.5 2.3 1.2 9.5 0.3 3.1 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF1049 PF06305.6 ETS61286.1 - 0.058 12.8 0.1 0.058 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PCI PF01399.22 ETS61287.1 - 2.4e-08 34.2 0.0 6.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain Phyto_Pns9_10 PF05878.6 ETS61289.1 - 0.24 10.3 0.1 0.45 9.4 0.1 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 CMAS PF02353.15 ETS61290.1 - 2.7e-65 220.1 0.0 6.1e-53 179.6 0.0 3.0 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 ETS61290.1 - 4.9e-10 39.9 0.0 2.4e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS61290.1 - 4.4e-09 36.2 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS61290.1 - 8e-07 29.4 0.0 2.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS61290.1 - 1.5e-06 27.8 0.0 4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS61290.1 - 0.00019 21.4 0.0 0.00061 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS61290.1 - 0.027 14.9 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 ETS61290.1 - 0.038 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 ETS61290.1 - 0.067 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 ETS61290.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 ETS61290.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CAP59_mtransfer PF11735.3 ETS61291.1 - 5.8e-77 258.1 0.5 8.2e-77 257.6 0.3 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_4 PF13704.1 ETS61291.1 - 0.014 15.7 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Scs3p PF10261.4 ETS61291.1 - 0.02 13.9 3.4 0.04 12.9 0.9 2.1 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Med10 PF09748.4 ETS61291.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Metallophos_C PF14008.1 ETS61292.1 - 2.7e-19 69.0 0.2 6.3e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 ETS61292.1 - 6.4e-17 61.6 0.5 1e-16 60.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS61292.1 - 4.4e-06 26.6 0.0 9e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 ETS61292.1 - 1.5e-05 23.7 0.0 2.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Ribosomal_L25p PF01386.14 ETS61292.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L25p family Fer2_3 PF13085.1 ETS61293.1 - 2.2e-31 107.9 0.0 3.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 ETS61293.1 - 3.8e-10 39.9 7.2 3.8e-10 39.9 5.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 ETS61293.1 - 1.2e-08 34.8 5.5 1.2e-08 34.8 3.8 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 ETS61293.1 - 9.2e-05 22.6 3.0 0.057 13.6 0.2 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 ETS61293.1 - 0.00027 21.2 3.6 0.00027 21.2 2.5 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 ETS61293.1 - 0.00036 20.2 4.8 0.00036 20.2 3.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 ETS61293.1 - 0.00063 20.0 4.9 0.00063 20.0 3.4 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 ETS61293.1 - 0.0066 16.1 0.5 0.0066 16.1 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 ETS61293.1 - 0.24 11.9 4.7 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain SH3_9 PF14604.1 ETS61294.1 - 7.5e-21 73.4 0.2 3.4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 ETS61294.1 - 2.5e-18 65.1 0.0 4.7e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 ETS61294.1 - 5.4e-16 57.8 0.0 3.1e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 ETS61294.1 - 1.5e-13 50.7 0.2 1.4e-12 47.6 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 ETS61294.1 - 8.3e-12 44.6 3.6 1.6e-11 43.7 2.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 ETS61294.1 - 0.02 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain GPI-anchored PF10342.4 ETS61294.1 - 0.069 13.6 0.2 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2417 PF10329.4 ETS61295.1 - 0.25 10.7 3.7 0.12 11.7 1.1 1.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) PrgI PF12666.2 ETS61295.1 - 1.7 8.8 5.3 4.8 7.3 0.0 2.6 3 0 0 3 3 3 0 PrgI family protein Complex1_LYR PF05347.10 ETS61296.1 - 1.9e-09 37.1 1.3 2.9e-09 36.5 0.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS61296.1 - 5.9e-09 36.0 1.2 9.2e-09 35.3 0.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like MFS_1 PF07690.11 ETS61297.1 - 7.3e-38 130.1 50.4 1.4e-37 129.2 32.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS61297.1 - 9.7e-12 43.8 23.4 2.2e-11 42.6 16.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4307 PF14155.1 ETS61297.1 - 6 6.6 7.0 0.6 9.9 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) Fungal_trans PF04082.13 ETS61298.1 - 3.8e-10 39.0 0.2 6e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61298.1 - 8e-07 28.8 9.1 8e-07 28.8 6.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS61299.1 - 9.1e-18 64.0 20.6 8.1e-10 37.9 3.3 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily CD34_antigen PF06365.7 ETS61299.1 - 0.034 13.7 0.1 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 CD34/Podocalyxin family Ferric_reduct PF01794.14 ETS61300.1 - 4.5e-15 55.8 14.8 4.5e-15 55.8 10.3 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS61300.1 - 1.8e-11 44.1 0.0 7.4e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS61300.1 - 2.5e-07 30.4 0.0 5.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 ETS61301.1 - 8.1e-16 58.2 17.7 8.1e-16 58.2 12.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS61301.1 - 2e-13 50.5 0.0 4.5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS61301.1 - 3.2e-05 23.7 0.0 7.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Alpha-L-AF_C PF06964.7 ETS61302.1 - 7e-38 130.1 0.0 1.3e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 ETS61302.1 - 1.6e-05 24.9 0.4 4e-05 23.6 0.3 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain Mak10 PF04112.8 ETS61303.1 - 9.5e-51 171.3 0.0 1.7e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AAA PF00004.24 ETS61305.1 - 1.3e-27 96.6 0.0 2.6e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS61305.1 - 2.3e-06 27.7 0.1 9.7e-06 25.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETS61305.1 - 4.6e-06 26.3 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETS61305.1 - 4.1e-05 23.2 0.1 0.00013 21.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS61305.1 - 5.5e-05 23.3 0.3 0.00054 20.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 ETS61305.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 ETS61305.1 - 0.00012 22.8 0.0 0.00031 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS61305.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 ETS61305.1 - 0.00032 20.1 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 ETS61305.1 - 0.001 17.8 0.0 0.002 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 ETS61305.1 - 0.0014 18.4 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ETS61305.1 - 0.0025 17.8 0.2 0.0064 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS61305.1 - 0.0025 16.9 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 ETS61305.1 - 0.0037 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2072 PF09845.4 ETS61305.1 - 0.0053 16.6 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) Mg_chelatase PF01078.16 ETS61305.1 - 0.0056 15.8 0.1 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETS61305.1 - 0.0062 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETS61305.1 - 0.011 16.0 0.0 0.038 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 ETS61305.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 ETS61305.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 ETS61305.1 - 0.025 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 ETS61305.1 - 0.027 13.9 0.0 0.089 12.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 ETS61305.1 - 0.03 13.5 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 ETS61305.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS61305.1 - 0.038 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 ETS61305.1 - 0.039 12.8 0.0 0.08 11.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 ETS61305.1 - 0.057 13.4 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 ETS61305.1 - 0.099 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Fe-S_biosyn PF01521.15 ETS61306.1 - 6e-17 61.5 0.0 8e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DEAD PF00270.24 ETS61307.1 - 4.6e-20 71.7 0.0 1.5e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS61307.1 - 0.00014 21.6 0.0 0.00049 19.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 ETS61307.1 - 0.26 10.3 0.0 0.44 9.5 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Carboxyl_trans PF01039.17 ETS61308.1 - 1.6e-108 363.2 0.0 2e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MFS_1 PF07690.11 ETS61309.1 - 4.7e-40 137.3 45.1 4.7e-40 137.3 31.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 ETS61309.1 - 1.9 7.7 12.3 0.071 12.4 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) CoA_transf_3 PF02515.12 ETS61310.1 - 1.5e-32 112.3 0.0 4.8e-28 97.7 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III CPSase_L_D2 PF02786.12 ETS61311.1 - 1.7e-58 197.3 0.0 2.8e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ETS61311.1 - 1.7e-33 115.0 0.9 4.8e-33 113.5 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS61311.1 - 2e-29 101.6 0.0 5e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 ETS61311.1 - 5.1e-12 45.9 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS61311.1 - 2.6e-11 43.3 0.0 4.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 ETS61311.1 - 3.6e-11 42.5 0.0 7.8e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 ETS61311.1 - 2.1e-07 30.0 0.0 3.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 ETS61311.1 - 8.6e-07 28.5 0.1 0.016 14.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 ETS61311.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 ETS61311.1 - 6.6e-05 22.3 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 ETS61311.1 - 0.022 13.9 0.0 0.29 10.2 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein Toxin_59 PF15537.1 ETS61311.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 59 Abhydrolase_6 PF12697.2 ETS61312.1 - 4.3e-09 36.5 0.7 4.3e-09 36.5 0.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS61312.1 - 1.3e-08 34.3 0.1 1.3e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS61312.1 - 1.5e-08 34.5 0.0 2.7e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 ETS61312.1 - 9.2e-06 24.7 0.2 8e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 ETS61312.1 - 2.9e-05 23.7 1.0 0.0033 17.0 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2456 PF10445.4 ETS61313.1 - 0.14 12.1 0.2 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) SNF2_N PF00176.18 ETS61314.1 - 7.1e-14 51.2 0.0 1.2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS61314.1 - 5.1e-06 26.4 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS61314.1 - 3.6e-05 23.5 0.0 7.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 ETS61314.1 - 0.079 11.9 0.0 0.18 10.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 ETS61315.1 - 1.5e-11 43.6 0.1 6.1e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS61315.1 - 0.00037 20.3 0.0 0.0017 18.2 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS61315.1 - 0.00047 19.9 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETS61316.1 - 9.5e-12 44.3 0.0 1.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS61316.1 - 5.8e-08 32.7 0.0 1.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS61316.1 - 2.5e-06 27.2 0.0 6.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_C48 PF02902.14 ETS61318.1 - 1.5e-15 57.4 0.5 3e-15 56.4 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Tet_JBP PF12851.2 ETS61319.1 - 3.5e-09 36.1 0.1 1.5e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Epimerase PF01370.16 ETS61320.1 - 1.7e-15 57.1 0.0 2.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS61320.1 - 1.4e-11 43.6 0.0 6e-11 41.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS61320.1 - 1.9e-11 43.4 0.0 3.1e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 ETS61320.1 - 0.001 18.3 0.0 0.0026 17.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family DUF3368 PF11848.3 ETS61320.1 - 0.072 12.6 0.5 0.44 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) NAD_binding_10 PF13460.1 ETS61321.1 - 7.6e-08 32.5 0.0 2.6e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS61321.1 - 0.00039 19.9 0.0 0.006 16.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 ETS61321.1 - 0.0072 16.6 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_5 PF12695.2 ETS61322.1 - 1.7e-11 44.0 0.0 2.1e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS61322.1 - 1.9e-11 44.2 0.1 2.5e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS61322.1 - 2.3e-06 27.0 0.0 8.4e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 ETS61322.1 - 2.4e-05 23.6 0.0 0.00024 20.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETS61322.1 - 0.00021 20.8 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 ETS61322.1 - 0.00081 19.0 0.1 0.0013 18.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 ETS61322.1 - 0.021 13.3 0.2 0.077 11.4 0.1 1.8 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 ETS61322.1 - 0.023 14.3 0.0 0.07 12.8 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 ETS61322.1 - 0.086 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PRCH PF03967.8 ETS61323.1 - 0.023 14.2 0.3 0.039 13.5 0.2 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Lactamase_B PF00753.22 ETS61324.1 - 4.2e-09 36.3 3.3 8.6e-09 35.3 2.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS61324.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain 2OG-FeII_Oxy_2 PF13532.1 ETS61325.1 - 1.2e-11 44.7 0.0 2.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETS61325.1 - 0.00026 21.2 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pribosyltran PF00156.22 ETS61326.1 - 1.1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Vps51 PF08700.6 ETS61327.1 - 1.3e-18 66.5 0.1 2.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 FlgN PF05130.7 ETS61327.1 - 0.034 14.3 0.5 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 FlgN protein Dor1 PF04124.7 ETS61327.1 - 0.11 10.9 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family COG5 PF10392.4 ETS61327.1 - 0.14 12.1 1.8 0.23 11.3 1.3 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Usp PF00582.21 ETS61328.1 - 2.3e-22 79.6 0.5 2.3e-22 79.6 0.3 2.7 3 0 0 3 3 3 1 Universal stress protein family Renin_r PF07850.9 ETS61328.1 - 0.065 13.5 0.1 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Renin receptor-like protein DUF2689 PF10894.3 ETS61329.1 - 0.083 12.6 0.1 0.89 9.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2689) Tho2 PF11262.3 ETS61330.1 - 4e-75 252.6 0.0 6.5e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 ETS61330.1 - 2.1e-28 97.9 0.1 7.9e-28 96.0 0.1 2.1 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SSPI PF14098.1 ETS61330.1 - 0.29 11.0 0.0 0.87 9.5 0.0 1.8 1 0 0 1 1 1 0 Small, acid-soluble spore protein I RhoGEF PF00621.15 ETS61331.1 - 9.5e-32 110.3 0.0 2.2e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain RRM_1 PF00076.17 ETS61332.1 - 2.6e-33 113.4 5.8 2.4e-18 65.5 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS61332.1 - 7.9e-28 96.2 0.2 3.6e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS61332.1 - 2.2e-12 46.6 1.9 5.2e-06 26.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 ETS61332.1 - 0.02 14.6 1.7 0.069 12.9 0.0 2.5 2 1 0 2 2 2 0 Limkain b1 LtrA PF06772.6 ETS61333.1 - 4e-14 52.3 25.4 4e-08 32.5 5.5 4.0 3 1 0 3 3 3 3 Bacterial low temperature requirement A protein (LtrA) Cyclin PF08613.6 ETS61333.1 - 0.22 11.9 1.7 0.35 11.2 0.1 2.0 2 0 0 2 2 2 0 Cyclin RabGAP-TBC PF00566.13 ETS61334.1 - 7.5e-49 166.1 0.2 1.4e-48 165.2 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MCLC PF05934.6 ETS61334.1 - 0.55 8.4 1.9 0.95 7.6 1.3 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) ABC2_membrane PF01061.19 ETS61335.1 - 1.1e-79 266.4 62.0 1.1e-43 148.8 16.1 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 ETS61335.1 - 2.6e-36 124.9 0.4 8e-18 65.0 0.0 3.5 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.7 ETS61335.1 - 8.4e-26 89.6 4.2 1.8e-20 72.5 0.0 3.1 3 0 0 3 3 3 2 CDR ABC transporter AAA_33 PF13671.1 ETS61335.1 - 1.4e-06 28.2 1.5 0.022 14.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 ETS61335.1 - 6.6e-06 25.3 10.4 6.6e-06 25.3 7.2 3.7 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 ETS61335.1 - 7.4e-06 25.9 0.4 7.4e-06 25.9 0.3 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_17 PF13207.1 ETS61335.1 - 7.5e-06 26.7 0.0 0.034 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS61335.1 - 9.8e-06 25.0 0.1 0.0093 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 ETS61335.1 - 2.4e-05 23.8 0.6 0.024 14.0 0.1 2.7 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 ETS61335.1 - 0.0001 22.4 0.0 0.038 13.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 ETS61335.1 - 0.00011 22.3 0.0 0.49 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 ETS61335.1 - 0.00026 20.5 0.0 0.25 10.7 0.0 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family DUF258 PF03193.11 ETS61335.1 - 0.0003 20.0 0.1 0.0064 15.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 ETS61335.1 - 0.00031 20.2 1.1 0.018 14.4 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 ETS61335.1 - 0.0019 17.5 0.1 0.023 13.9 0.0 2.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 ETS61335.1 - 0.0038 17.5 1.7 0.59 10.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 ETS61335.1 - 0.006 16.5 3.0 0.45 10.4 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain UPF0079 PF02367.12 ETS61335.1 - 0.0084 15.7 0.5 2 8.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 ETS61335.1 - 0.009 15.6 0.8 3.3 7.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 ETS61335.1 - 0.036 13.1 0.3 2.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 ETS61335.1 - 0.038 13.4 0.4 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 ETS61335.1 - 0.07 13.3 1.0 14 5.8 0.0 3.4 3 0 0 3 3 3 0 RNA helicase SbcCD_C PF13558.1 ETS61335.1 - 0.077 12.9 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 ETS61335.1 - 0.11 12.4 0.3 15 5.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 ETS61335.1 - 0.13 12.4 0.1 17 5.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 ETS61335.1 - 0.18 11.7 5.8 0.14 12.1 0.1 3.0 4 0 0 4 4 2 0 AAA domain AAA_19 PF13245.1 ETS61335.1 - 0.38 10.5 2.5 8.6 6.1 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 ETS61335.1 - 0.93 9.7 0.0 0.93 9.7 0.0 3.5 5 0 0 5 5 4 0 AAA domain Complex1_LYR_1 PF13232.1 ETS61336.1 - 1.5e-07 31.5 4.3 2.5e-07 30.8 3.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 ETS61336.1 - 4.5e-07 29.5 7.4 8.7e-07 28.6 5.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) tRNA-synt_1 PF00133.17 ETS61336.1 - 0.12 10.2 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WD40 PF00400.27 ETS61337.1 - 0.043 13.7 1.1 0.68 9.9 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat HhH-GPD PF00730.20 ETS61338.1 - 1.2e-08 35.1 0.0 1.7e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Palm_thioest PF02089.10 ETS61339.1 - 1e-56 191.9 0.0 1.4e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 ETS61339.1 - 1.1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 ETS61339.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 ETS61339.1 - 0.031 13.8 0.1 0.071 12.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2910 PF11139.3 ETS61339.1 - 0.057 12.5 1.5 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Clat_adaptor_s PF01217.15 ETS61340.1 - 1.1e-17 64.0 0.1 1.7e-15 56.9 0.0 2.2 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 ETS61341.1 - 1e-77 260.7 0.0 1.4e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61341.1 - 3.3e-44 150.9 0.0 4.6e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS61341.1 - 6.8e-12 44.9 0.0 1.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS61341.1 - 0.0017 17.4 0.0 0.0074 15.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RabGAP-TBC PF00566.13 ETS61342.1 - 1.8e-20 73.3 0.8 1.2e-16 60.8 0.6 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sporozoite_P67 PF05642.6 ETS61342.1 - 4 5.1 15.5 5.7 4.6 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.11 ETS61344.1 - 8e-26 90.5 32.7 1.1e-25 90.1 22.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS61344.1 - 0.00043 20.0 1.3 0.0012 18.6 0.2 2.3 2 0 0 2 2 2 1 MFS_1 like family DUF1228 PF06779.9 ETS61344.1 - 0.023 14.7 2.0 0.11 12.5 1.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) Sugar_tr PF00083.19 ETS61344.1 - 0.069 11.7 26.0 0.35 9.3 4.1 2.4 1 1 1 2 2 2 0 Sugar (and other) transporter NifU_N PF01592.11 ETS61349.1 - 7.5e-52 174.5 0.1 1.2e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L11 PF00298.14 ETS61350.1 - 1.4e-27 95.6 2.3 2.3e-27 94.8 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 ETS61350.1 - 3.8e-23 80.6 0.5 3.8e-23 80.6 0.3 2.2 4 0 0 4 4 4 1 Ribosomal protein L11, N-terminal domain Proteasome PF00227.21 ETS61351.1 - 7.2e-60 201.5 0.0 1.9e-59 200.1 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS61351.1 - 2.8e-10 39.2 0.2 7.7e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RabGAP-TBC PF00566.13 ETS61352.1 - 9.3e-18 64.4 0.0 2.6e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ras PF00071.17 ETS61353.1 - 4.9e-46 156.0 0.6 5.9e-46 155.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS61353.1 - 3.8e-15 56.4 0.1 5.6e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61353.1 - 1.1e-06 27.9 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS61353.1 - 2.5e-06 27.4 0.0 3.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS61353.1 - 0.00015 21.2 0.5 0.00077 18.9 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETS61353.1 - 0.0015 17.8 0.1 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 ETS61353.1 - 0.0086 15.3 0.1 0.12 11.6 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 ETS61353.1 - 0.058 13.0 0.1 0.075 12.7 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase Rpr2 PF04032.11 ETS61354.1 - 1.6e-12 47.0 1.0 2.6e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Optomotor-blind PF11078.3 ETS61354.1 - 0.2 12.0 4.3 0.13 12.6 1.4 1.9 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region Gastrin PF00918.12 ETS61354.1 - 0.61 10.9 3.5 2.1 9.1 2.4 1.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Glyco_hydro_cc PF11790.3 ETS61355.1 - 6.6e-55 186.1 10.5 9.7e-55 185.5 7.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 ETS61355.1 - 0.00034 19.4 0.4 0.00064 18.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DUF4253 PF14062.1 ETS61355.1 - 0.0078 15.8 0.2 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4253) DUF2217 PF10265.4 ETS61355.1 - 1.8 7.2 11.7 3.3 6.3 8.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3245 PF11595.3 ETS61355.1 - 2.2 8.5 13.9 0.14 12.4 6.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DNA_pol_viral_N PF00242.12 ETS61355.1 - 2.9 6.8 12.9 4.7 6.1 8.9 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 ETS61355.1 - 3.6 5.7 18.2 5.6 5.1 12.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Peptidase_C13 PF01650.13 ETS61357.1 - 7.7e-40 136.8 0.0 1.1e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF4447 PF14590.1 ETS61357.1 - 0.24 10.9 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) RRM_1 PF00076.17 ETS61358.1 - 2.7e-27 94.2 0.0 5.2e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS61358.1 - 6.5e-22 77.3 0.0 2.2e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS61358.1 - 5.2e-12 45.4 0.0 3.7e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 ETS61358.1 - 0.00015 21.4 0.4 0.058 13.1 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 ETS61358.1 - 0.0018 18.1 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 ETS61358.1 - 0.057 13.1 0.0 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SH3_1 PF00018.23 ETS61359.1 - 4.6e-23 80.3 0.0 1.9e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 ETS61359.1 - 8.2e-15 54.1 0.0 2.6e-06 26.9 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 ETS61359.1 - 3e-14 52.2 0.0 2.7e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 ETS61359.1 - 3.9e-09 36.3 0.0 1.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 PX domain PB1 PF00564.19 ETS61359.1 - 0.094 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Macoilin PF09726.4 ETS61359.1 - 4.1 5.5 4.9 6.2 4.9 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Adap_comp_sub PF00928.16 ETS61360.1 - 1.7e-42 145.3 0.0 2.3e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETS61360.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DNA_RNApol_7kD PF03604.8 ETS61361.1 - 1.7e-16 59.3 5.9 2.5e-16 58.8 4.1 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 ETS61361.1 - 0.037 13.7 0.2 0.052 13.2 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 ETS61361.1 - 0.047 13.7 0.8 0.047 13.7 0.5 1.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.5 ETS61361.1 - 0.083 12.8 2.5 0.22 11.5 1.8 1.7 1 1 0 1 1 1 0 Zinc ribbon domain DZR PF12773.2 ETS61361.1 - 0.13 12.1 0.7 0.2 11.4 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF2197 PF09963.4 ETS61361.1 - 3.1 7.8 5.7 15 5.6 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) BOP1NT PF08145.7 ETS61362.1 - 8.3e-106 353.4 3.7 1.3e-105 352.8 2.5 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 ETS61362.1 - 4.6e-22 77.0 13.8 1.5e-06 27.8 0.3 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Actin PF00022.14 ETS61363.1 - 5.6e-114 380.6 0.0 9.9e-114 379.8 0.0 1.4 1 1 0 1 1 1 1 Actin adh_short_C2 PF13561.1 ETS61364.1 - 2.9e-30 105.8 0.1 3.9e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS61364.1 - 7.6e-28 97.5 2.0 1.2e-27 96.8 1.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS61364.1 - 9.7e-17 61.1 1.8 1.4e-16 60.7 0.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS61364.1 - 4.5e-05 22.9 0.1 6.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS61364.1 - 0.00021 21.3 0.3 0.0043 17.0 0.2 2.1 2 0 0 2 2 2 1 NADH(P)-binding SBP_bac_5 PF00496.17 ETS61364.1 - 0.0017 17.2 0.0 0.003 16.4 0.0 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle 3HCDH_N PF02737.13 ETS61364.1 - 0.0034 17.0 0.6 0.52 9.9 0.7 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 ETS61364.1 - 0.0044 15.9 0.3 0.0067 15.3 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 ETS61364.1 - 0.012 14.6 0.4 0.11 11.4 0.2 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 ETS61364.1 - 0.018 15.4 1.4 6.2 7.3 0.1 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Rot1 PF10681.4 ETS61366.1 - 1.7e-62 210.5 0.4 2.1e-62 210.2 0.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF2611 PF11022.3 ETS61366.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) SKN1 PF03935.10 ETS61367.1 - 2e-196 653.0 0.5 2.6e-196 652.6 0.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Avidin PF01382.12 ETS61367.1 - 4.1 7.7 7.9 9 6.6 0.1 2.7 3 0 0 3 3 3 0 Avidin family DAO PF01266.19 ETS61369.1 - 9.7e-19 67.4 0.1 4.5e-11 42.2 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS61369.1 - 0.00066 19.6 0.0 0.0085 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS61369.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS61369.1 - 0.0028 16.5 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS61369.1 - 0.0042 17.0 0.1 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS61369.1 - 0.03 13.4 0.0 0.096 11.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 ETS61369.1 - 0.056 12.4 0.0 0.24 10.3 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 ETS61369.1 - 0.099 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 ETS61369.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 ETS61369.1 - 0.12 11.9 0.1 0.65 9.6 0.0 2.0 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2OG-FeII_Oxy PF03171.15 ETS61370.1 - 1.8e-22 79.4 0.0 3.3e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS61370.1 - 6.6e-19 68.5 0.0 1.1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PMP1_2 PF08114.6 ETS61371.1 - 0.0011 18.4 0.3 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 ATPase proteolipid family DUF262 PF03235.9 ETS61372.1 - 1.6e-13 51.1 0.0 3.1e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF262 DUF1378 PF07125.6 ETS61372.1 - 0.12 12.3 0.2 0.41 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) DUF1748 PF08520.5 ETS61373.1 - 2.2e-28 97.7 0.0 3.3e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Pkinase PF00069.20 ETS61374.1 - 4.5e-69 232.4 0.0 7e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61374.1 - 1.4e-30 106.2 0.0 2.2e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS61374.1 - 1.2e-10 40.8 0.6 1.1e-06 27.8 0.0 3.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 ETS61374.1 - 0.024 13.7 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS61374.1 - 0.16 11.7 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3454 PF11936.3 ETS61374.1 - 7.5 6.8 24.3 0.4 10.9 8.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3454) Sedlin_N PF04628.8 ETS61375.1 - 1e-33 116.0 0.0 4e-33 114.0 0.0 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 ETS61375.1 - 0.00015 21.5 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Sybindin-like family Avl9 PF09794.4 ETS61375.1 - 0.096 11.1 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 bZIP_1 PF00170.16 ETS61376.1 - 1.6e-07 31.1 16.9 4e-07 29.9 11.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor eIF3_subunit PF08597.5 ETS61376.1 - 0.011 15.3 1.5 0.014 14.9 1.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit bZIP_2 PF07716.10 ETS61376.1 - 0.02 14.7 24.5 0.11 12.3 8.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF904 PF06005.7 ETS61376.1 - 0.021 15.0 3.0 0.021 15.0 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_Maf PF03131.12 ETS61376.1 - 0.086 13.1 18.6 0.32 11.3 12.9 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.6 ETS61376.1 - 0.12 12.2 0.4 0.28 11.0 0.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 ETS61376.1 - 0.16 11.8 12.0 0.075 12.8 3.8 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 ETS61376.1 - 0.2 11.8 4.8 0.28 11.3 3.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.10 ETS61376.1 - 0.44 10.2 5.6 0.68 9.6 3.5 1.6 1 1 0 1 1 1 0 RasGAP C-terminus DUF724 PF05266.9 ETS61376.1 - 0.44 10.1 10.8 0.67 9.5 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 ETS61376.1 - 0.66 7.7 3.1 0.83 7.4 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fucose_iso_N2 PF07882.7 ETS61376.1 - 1 8.9 4.4 1.9 8.1 3.1 1.4 1 1 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF1640 PF07798.6 ETS61376.1 - 1.1 9.2 6.4 1.6 8.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CDC37_N PF03234.9 ETS61376.1 - 2.1 8.6 7.0 3.7 7.8 4.9 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4239 PF14023.1 ETS61376.1 - 2.3 7.5 4.0 3 7.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) APG6 PF04111.7 ETS61376.1 - 9.7 5.1 10.9 13 4.6 7.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GTP_EFTU PF00009.22 ETS61377.1 - 1.7e-46 158.0 0.0 2.9e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS61377.1 - 1.1e-26 92.9 0.2 4.5e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS61377.1 - 1.2e-10 41.3 0.8 2.9e-10 40.1 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS61377.1 - 0.00013 21.8 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 ETS61377.1 - 0.0042 16.7 0.3 0.01 15.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 DNA_pol3_chi PF04364.8 ETS61377.1 - 0.014 15.2 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC Miro PF08477.8 ETS61377.1 - 0.072 13.5 0.1 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DAD PF02109.11 ETS61378.1 - 5e-48 161.8 1.2 6.1e-48 161.5 0.8 1.0 1 0 0 1 1 1 1 DAD family Rho_GDI PF02115.12 ETS61379.1 - 9.4e-61 204.7 0.0 1.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TauD PF02668.11 ETS61380.1 - 7.7e-58 196.1 0.4 1.8e-57 194.9 0.2 1.6 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UbiA PF01040.13 ETS61380.1 - 2.3e-24 86.0 25.5 2.3e-24 86.0 17.6 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF1640 PF07798.6 ETS61380.1 - 2e-16 60.5 1.3 3.5e-16 59.7 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Cu_amine_oxidN1 PF07833.6 ETS61380.1 - 0.031 14.6 0.1 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain Fzo_mitofusin PF04799.8 ETS61380.1 - 0.38 10.1 2.2 0.68 9.2 1.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4404 PF14357.1 ETS61380.1 - 1.4 9.3 6.6 4.8 7.6 4.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) HTH_31 PF13560.1 ETS61381.1 - 0.64 10.2 5.7 0.29 11.3 2.2 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Pyr_redox PF00070.22 ETS61384.1 - 3.1e-15 56.3 0.1 9e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS61384.1 - 3.8e-14 53.0 0.0 3.5e-13 49.8 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS61384.1 - 2.4e-12 47.3 0.4 1.5e-05 25.1 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS61384.1 - 2.4e-07 29.9 0.8 0.0069 15.3 0.2 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS61384.1 - 2.5e-05 23.3 0.3 0.0003 19.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 ETS61384.1 - 0.00037 20.7 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.9 ETS61384.1 - 0.0009 17.9 0.7 0.28 9.7 0.1 3.1 3 0 0 3 3 3 1 Tryptophan halogenase TrkA_N PF02254.13 ETS61384.1 - 0.0046 16.9 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.1 ETS61384.1 - 0.047 13.4 5.7 1.3 8.7 0.0 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding ApbA PF02558.11 ETS61384.1 - 0.093 12.1 0.3 0.61 9.5 0.1 2.4 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 ETS61384.1 - 0.13 11.1 0.7 10 4.9 0.2 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein SRPRB PF09439.5 ETS61385.1 - 1.6e-12 46.9 0.1 4e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.16 ETS61385.1 - 2.6e-07 30.0 0.0 3.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS61385.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS61385.1 - 2e-05 24.1 0.2 0.00072 19.0 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 ETS61385.1 - 3.8e-05 24.1 0.0 0.00053 20.4 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 ETS61385.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 ETS61385.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Ras family Proteasome PF00227.21 ETS61386.1 - 7.9e-46 155.7 0.0 9.6e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS61386.1 - 2.3e-13 49.1 0.0 4.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Apolipoprotein PF01442.13 ETS61387.1 - 6.8e-05 22.4 14.5 0.00011 21.8 10.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 ETS61387.1 - 0.004 17.5 1.5 0.004 17.5 1.1 3.7 2 1 3 5 5 5 4 Bacterial protein of unknown function (DUF883) DBINO PF13892.1 ETS61387.1 - 0.024 14.6 26.4 0.022 14.7 10.8 2.2 1 1 1 2 2 2 0 DNA-binding domain DUF2390 PF09523.5 ETS61387.1 - 1.2 9.3 5.5 0.17 12.0 0.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2390) ATP-synt_B PF00430.13 ETS61387.1 - 3.8 7.3 38.3 0.12 12.2 5.5 3.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) SART-1 PF03343.8 ETS61388.1 - 5.7e-137 457.6 47.9 7.8e-137 457.2 33.2 1.2 1 0 0 1 1 1 1 SART-1 family PQ-loop PF04193.9 ETS61389.1 - 6.9e-33 111.9 0.7 3.6e-17 61.6 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat UPF0113 PF03657.8 ETS61390.1 - 2.5e-09 37.0 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Utp14 PF04615.8 ETS61391.1 - 1.6e-156 522.5 41.5 1.6e-156 522.5 28.8 2.4 1 1 1 2 2 2 1 Utp14 protein Tho2 PF11262.3 ETS61391.1 - 1.9 7.4 6.4 3.2 6.7 4.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RhoGAP PF00620.22 ETS61392.1 - 4.3e-25 88.1 0.0 7.2e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Senescence_reg PF04520.8 ETS61393.1 - 0.063 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Senescence regulator Peptidase_M23 PF01551.17 ETS61393.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M23 Y_phosphatase PF00102.22 ETS61394.1 - 5.4e-40 137.1 0.0 7.1e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 ETS61394.1 - 0.0064 16.0 1.1 0.016 14.7 0.5 1.8 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain DSBA PF01323.15 ETS61395.1 - 5.8e-30 104.3 0.1 6.5e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF4164 PF13747.1 ETS61395.1 - 0.095 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) HpcH_HpaI PF03328.9 ETS61396.1 - 1.9e-41 141.3 0.2 2.5e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 ETS61396.1 - 3.1e-11 42.6 0.3 0.00016 20.5 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Aminotran_1_2 PF00155.16 ETS61397.1 - 2.5e-48 164.8 0.0 3.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS61397.1 - 0.0064 15.6 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase PQ-loop PF04193.9 ETS61398.1 - 5.2e-22 77.1 5.0 4.9e-15 54.8 0.0 3.2 2 1 1 3 3 3 2 PQ loop repeat Pex24p PF06398.6 ETS61398.1 - 0.093 11.5 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF2803 PF10972.3 ETS61398.1 - 0.28 10.6 7.5 3.2 7.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2803) HSD3 PF15244.1 ETS61398.1 - 0.41 9.8 4.3 0.092 11.9 0.4 1.6 2 0 0 2 2 2 0 Hydroxy-steroid dehydrogenase Shisa PF13908.1 ETS61398.1 - 0.47 10.6 2.7 28 4.8 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Endonuclease_NS PF01223.18 ETS61399.1 - 3.8e-51 173.6 0.0 5.9e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease E1_dh PF00676.15 ETS61400.1 - 1.9e-88 296.0 0.1 2.3e-88 295.7 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 ETS61400.1 - 2e-06 26.8 0.0 3.1e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 ETS61400.1 - 0.002 17.1 0.0 0.0079 15.1 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Amidase02_C PF12123.3 ETS61400.1 - 0.11 12.1 0.5 0.25 10.9 0.3 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Aminotran_3 PF00202.16 ETS61402.1 - 4.2e-78 262.5 0.0 6.2e-78 262.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III TmoB PF06234.7 ETS61402.1 - 0.056 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Pox_I6 PF04595.8 ETS61402.1 - 0.17 10.6 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family GFO_IDH_MocA PF01408.17 ETS61403.1 - 1.3e-20 74.0 0.1 2.1e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 ETS61403.1 - 0.013 15.8 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.11 ETS61403.1 - 0.016 15.7 0.3 0.046 14.2 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_3 PF03447.11 ETS61403.1 - 0.032 14.6 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Big_5 PF13205.1 ETS61403.1 - 0.053 14.1 0.8 0.11 13.1 0.5 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain Pex19 PF04614.7 ETS61404.1 - 3.4e-66 223.4 5.2 3.4e-66 223.4 3.6 1.7 1 1 0 2 2 2 1 Pex19 protein family RasGAP_C PF03836.10 ETS61405.1 - 3.1e-47 159.8 5.8 8.6e-47 158.3 4.1 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 ETS61405.1 - 2.4e-41 141.5 0.0 6.8e-41 140.0 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 ETS61405.1 - 1.6e-25 86.2 45.2 0.007 15.9 0.3 12.4 11 1 1 12 12 12 11 IQ calmodulin-binding motif CH PF00307.26 ETS61405.1 - 2e-11 43.9 0.0 5.3e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain zf-NPL4 PF05020.10 ETS61405.1 - 0.15 11.7 2.4 0.18 11.4 0.5 2.0 2 0 0 2 2 2 0 NPL4 family, putative zinc binding region Peptidase_M24 PF00557.19 ETS61407.1 - 3.4e-27 95.3 0.3 5.2e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SH3_2 PF07653.12 ETS61407.1 - 0.0028 17.1 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.17 ETS61408.1 - 4.2e-75 253.0 0.0 7.6e-59 199.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Endosulfine PF04667.12 ETS61409.1 - 1.5e-19 69.7 0.0 2.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Porin_3 PF01459.17 ETS61410.1 - 1.3e-67 228.0 0.5 1.5e-67 227.7 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Hpt PF01627.18 ETS61412.1 - 9.1e-10 38.4 0.1 1.8e-09 37.4 0.1 1.6 1 1 0 1 1 1 1 Hpt domain Paf1 PF03985.8 ETS61412.1 - 0.038 12.7 4.2 0.061 12.0 2.9 1.3 1 0 0 1 1 1 0 Paf1 Arrestin_C PF02752.17 ETS61413.1 - 3.1e-12 46.7 2.4 1.3e-11 44.7 1.3 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS61413.1 - 7.4e-10 38.8 0.4 0.00047 20.0 0.2 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 ETS61413.1 - 0.046 12.7 0.9 6.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Rgp1 DDHD PF02862.12 ETS61414.1 - 9.7e-46 156.3 0.0 9.7e-46 156.3 0.0 3.6 3 1 0 3 3 3 1 DDHD domain Cupin_8 PF13621.1 ETS61415.1 - 3.5e-21 75.8 0.0 6.4e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETS61415.1 - 9.6e-08 31.6 0.0 3.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 ETS61415.1 - 0.04 14.1 0.0 0.37 11.0 0.0 2.5 2 1 0 2 2 2 0 JmjC domain, hydroxylase Tcp11 PF05794.8 ETS61417.1 - 1e-64 218.9 0.0 4.6e-47 160.7 0.0 3.6 3 1 0 3 3 3 3 T-complex protein 11 NIF PF03031.13 ETS61418.1 - 3.6e-52 176.2 0.1 5.2e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HLH PF00010.21 ETS61419.1 - 9.3e-18 63.6 1.5 2.4e-17 62.3 1.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.7 ETS61419.1 - 0.16 9.8 12.4 0.057 11.3 3.5 2.2 2 0 0 2 2 2 0 Nop14-like family AIP3 PF03915.8 ETS61419.1 - 0.36 9.6 6.7 2.6 6.8 1.9 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 Phyto_Pns9_10 PF05878.6 ETS61419.1 - 0.91 8.4 3.7 2.5 6.9 2.6 1.7 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 PEMT PF04191.8 ETS61421.1 - 3.6e-33 113.8 4.5 8.2e-33 112.6 3.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Pkinase PF00069.20 ETS61422.1 - 1.7e-64 217.4 0.0 1.3e-63 214.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61422.1 - 7.1e-34 117.0 0.0 1.3e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 ETS61422.1 - 2.1e-25 88.2 15.6 3.7e-14 52.2 7.1 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 ETS61422.1 - 5.6e-20 70.8 26.2 1.5e-10 40.6 6.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 ETS61422.1 - 5.5e-08 33.2 0.4 2e-07 31.3 0.3 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETS61422.1 - 0.0027 16.7 0.0 0.0057 15.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.1 ETS61422.1 - 0.45 10.5 10.8 0.5 10.3 2.4 2.6 2 0 0 2 2 2 0 Up-regulated During Septation RhoGAP PF00620.22 ETS61423.1 - 5.7e-10 39.0 0.0 4.3e-09 36.1 0.0 2.4 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.18 ETS61423.1 - 7.4e-05 22.8 0.5 0.0011 19.1 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RIO1 PF01163.17 ETS61424.1 - 3.3e-69 232.0 0.0 3.3e-69 232.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 ETS61424.1 - 0.028 13.5 0.0 0.069 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein kinase domain Hist_deacetyl PF00850.14 ETS61425.1 - 1.3e-53 182.3 9.8 9e-53 179.5 6.8 2.0 1 1 0 1 1 1 1 Histone deacetylase domain PQ-loop PF04193.9 ETS61427.1 - 4.3e-28 96.6 1.2 3.6e-13 48.8 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF202 PF02656.10 ETS61427.1 - 0.059 13.5 1.0 0.21 11.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3185 PF11381.3 ETS61427.1 - 0.092 12.5 4.1 3.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF973 PF06157.6 ETS61427.1 - 0.1 11.5 1.1 0.14 11.0 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF4199 PF13858.1 ETS61427.1 - 7.7 6.4 10.4 1.1 9.1 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Ras PF00071.17 ETS61431.1 - 4.5e-57 191.9 0.0 5.2e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS61431.1 - 7.3e-16 58.7 0.0 9.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61431.1 - 3.1e-07 29.7 0.0 4.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 ETS61431.1 - 0.00064 18.9 0.0 0.00087 18.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETS61431.1 - 0.046 12.8 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Asp PF00026.18 ETS61433.1 - 8.5e-17 61.3 0.0 2.1e-11 43.6 0.3 2.6 2 0 0 2 2 2 2 Eukaryotic aspartyl protease DUF4381 PF14316.1 ETS61433.1 - 7 6.7 8.1 0.31 11.1 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-C3HC4_3 PF13920.1 ETS61434.1 - 8.1e-10 38.2 16.4 1.5e-09 37.3 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS61434.1 - 8.3 6.5 18.4 16 5.6 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_N PF08240.7 ETS61435.1 - 1e-31 108.8 0.2 2e-31 107.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS61435.1 - 3.9e-19 68.4 0.3 1e-18 67.1 0.2 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 ETS61435.1 - 0.0084 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.1 ETS61435.1 - 0.026 14.1 0.2 0.067 12.8 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 ETS61435.1 - 0.06 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_18 PF12847.2 ETS61435.1 - 0.14 12.7 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 ETS61436.1 - 1.1e-35 122.4 0.0 1.8e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family DAO PF01266.19 ETS61436.1 - 0.024 13.5 1.4 0.069 12.0 0.1 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS61436.1 - 0.038 13.0 0.1 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PHZA_PHZB PF03284.8 ETS61436.1 - 0.074 12.1 0.1 0.29 10.1 0.1 2.0 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B ApbA PF02558.11 ETS61436.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ILVD_EDD PF00920.16 ETS61437.1 - 1.6e-188 627.3 1.3 7.6e-187 621.8 0.9 2.0 1 1 0 1 1 1 1 Dehydratase family zf-TFIIB PF13453.1 ETS61437.1 - 0.2 10.8 3.6 10 5.4 0.2 2.8 2 0 0 2 2 2 0 Transcription factor zinc-finger Mucin PF01456.12 ETS61438.1 - 0.042 13.6 19.6 0.057 13.1 13.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein InvH PF04741.7 ETS61438.1 - 0.058 13.2 3.0 0.11 12.3 2.1 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF1183 PF06682.7 ETS61438.1 - 0.14 11.7 1.7 0.16 11.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SOG2 PF10428.4 ETS61438.1 - 0.22 10.1 4.8 0.23 10.0 3.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.5 ETS61438.1 - 3 7.4 8.4 3.2 7.3 5.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF788 PF05620.6 ETS61439.1 - 5.5e-44 150.0 1.9 7.1e-44 149.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) OB_NTP_bind PF07717.11 ETS61441.1 - 6e-26 90.5 0.0 1.5e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS61441.1 - 8.1e-26 90.0 0.8 3.3e-24 84.8 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS61441.1 - 6.2e-13 48.4 0.0 1.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS61441.1 - 2.7e-06 26.9 0.0 6.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS61441.1 - 0.0001 22.4 0.2 0.0045 17.1 0.1 3.3 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS61441.1 - 0.00045 19.1 0.1 0.00092 18.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 ETS61441.1 - 0.043 13.5 0.1 0.2 11.4 0.1 2.2 1 0 0 1 1 1 0 Part of AAA domain Atg14 PF10186.4 ETS61442.1 - 5.2e-24 84.7 2.4 4.3e-13 48.8 0.0 2.9 2 1 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 zf-rbx1 PF12678.2 ETS61443.1 - 1.8e-17 63.1 6.0 2.4e-17 62.8 4.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS61443.1 - 3.4e-06 26.8 3.2 4.6e-06 26.3 2.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger VSP PF03302.8 ETS61443.1 - 0.012 14.3 2.8 0.013 14.1 2.0 1.0 1 0 0 1 1 1 0 Giardia variant-specific surface protein WD40 PF00400.27 ETS61444.1 - 7e-45 149.3 26.5 7.3e-07 28.8 0.0 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat CTP_transf_2 PF01467.21 ETS61444.1 - 2e-08 34.4 0.1 1.6e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 ETS61444.1 - 0.23 11.0 0.0 0.49 10.0 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase ATE_C PF04377.10 ETS61445.1 - 1.2e-46 157.9 0.1 1.8e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 ETS61445.1 - 2.8e-23 81.4 1.9 5.3e-23 80.6 0.6 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus DSS1_SEM1 PF05160.8 ETS61446.1 - 3.7e-18 65.0 10.9 1.1e-11 44.3 1.6 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family DUF1681 PF07933.9 ETS61447.1 - 1.7e-57 193.4 0.0 2.1e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF3712 PF12505.3 ETS61448.1 - 1.2e-33 115.8 0.0 7.8e-21 74.3 0.0 5.3 5 0 0 5 5 5 3 Protein of unknown function (DUF3712) LEA_2 PF03168.8 ETS61448.1 - 1.1e-05 25.7 0.0 0.031 14.6 0.0 5.0 5 0 0 5 5 5 1 Late embryogenesis abundant protein Apc4 PF12896.2 ETS61449.1 - 2.1e-30 105.6 0.0 3.8e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ETF PF01012.16 ETS61450.1 - 9e-40 136.0 0.2 1.5e-39 135.3 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 ETS61450.1 - 2.2e-35 120.1 0.3 4.3e-35 119.1 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DHHA1 PF02272.14 ETS61451.1 - 0.0013 18.3 0.1 0.016 14.8 0.0 2.5 1 1 0 1 1 1 1 DHHA1 domain DHH PF01368.15 ETS61451.1 - 0.0023 17.5 0.0 0.0062 16.1 0.0 1.7 1 1 0 1 1 1 1 DHH family Rdx PF10262.4 ETS61452.1 - 3.1e-11 43.1 0.0 4.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family EB1 PF03271.12 ETS61455.1 - 2.5e-15 56.2 0.4 5.7e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 ETS61455.1 - 1.7e-05 24.8 0.1 3.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain PhaP_Bmeg PF09602.5 ETS61455.1 - 0.011 15.5 0.1 0.024 14.4 0.0 1.6 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF3138 PF11336.3 ETS61455.1 - 1.3 7.0 5.3 0.99 7.5 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Homeobox PF00046.24 ETS61456.1 - 7.5e-12 44.6 1.5 1.6e-11 43.6 1.0 1.6 1 0 0 1 1 1 1 Homeobox domain SLAC1 PF03595.12 ETS61457.1 - 3e-46 157.6 43.5 2.2e-31 108.7 13.6 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel Mito_carr PF00153.22 ETS61458.1 - 7.7e-31 105.6 6.8 8.2e-14 51.0 0.0 3.2 2 1 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb2_6 PF00562.23 ETS61458.1 - 0.14 10.8 0.1 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 NAD_binding_8 PF13450.1 ETS61459.1 - 7.5e-11 41.8 0.0 1.9e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS61459.1 - 0.0062 16.3 0.3 0.16 11.7 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Fungal_trans PF04082.13 ETS61460.1 - 5.1e-10 38.6 0.8 9.6e-10 37.7 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61460.1 - 0.0008 19.2 10.3 0.0013 18.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribophorin_I PF04597.9 ETS61461.1 - 4.4e-111 371.4 0.0 5e-111 371.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I CDC45 PF02724.9 ETS61462.1 - 2.6e-195 650.0 0.0 3.1e-195 649.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein RasGEF PF00617.14 ETS61463.1 - 6.9e-44 149.8 0.0 1.1e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETS61463.1 - 8.2e-07 29.0 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 ETS61463.1 - 0.00022 21.7 0.0 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61463.1 - 0.046 12.9 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family MobB PF03205.9 ETS61463.1 - 0.1 12.3 0.2 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.17 ETS61463.1 - 0.13 11.6 0.1 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 Ras family p450 PF00067.17 ETS61464.1 - 1.2e-66 225.2 0.0 1.6e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIN_2 PF10130.4 ETS61464.1 - 0.03 14.3 0.0 0.092 12.7 0.0 1.8 1 0 0 1 1 1 0 PIN domain Fungal_trans PF04082.13 ETS61465.1 - 3.8e-11 42.3 0.0 9.4e-11 41.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61465.1 - 3.3e-08 33.3 9.7 5.9e-08 32.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tnp_zf-ribbon_2 PF13842.1 ETS61465.1 - 2.1 8.8 10.0 4.3 7.8 6.9 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Acetyltransf_1 PF00583.19 ETS61466.1 - 2.8e-14 52.9 0.0 4.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS61466.1 - 3.7e-11 43.0 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS61466.1 - 2.3e-07 30.8 0.0 3.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS61466.1 - 2.5e-06 27.6 0.0 3.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS61466.1 - 5.2e-06 26.5 0.1 6.7e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS61466.1 - 4.2e-05 23.5 0.0 6.5e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS61466.1 - 0.0008 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 ETS61466.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Arrestin_C PF02752.17 ETS61467.1 - 4.1e-09 36.6 0.7 8.9e-08 32.3 0.1 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS61467.1 - 0.00056 19.7 0.0 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Nuc_sug_transp PF04142.10 ETS61469.1 - 2.2e-45 154.6 3.3 2.2e-45 154.6 2.3 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 ETS61469.1 - 2.6e-06 27.6 0.6 2.6e-06 27.6 0.4 3.6 3 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 ETS61469.1 - 1.7e-05 24.5 1.0 1.7e-05 24.5 0.7 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 ETS61469.1 - 0.0096 15.9 1.3 0.0096 15.9 0.9 3.2 3 1 0 3 3 3 1 EamA-like transporter family Acyl_transf_3 PF01757.17 ETS61470.1 - 4e-11 42.3 33.2 6e-11 41.7 23.0 1.2 1 0 0 1 1 1 1 Acyltransferase family Glyco_transf_90 PF05686.7 ETS61471.1 - 1.5e-18 66.7 0.7 1.5e-15 56.8 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 DUF3315 PF11776.3 ETS61471.1 - 0.082 12.4 3.7 0.097 12.2 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3315) Ribosomal_L22 PF00237.14 ETS61473.1 - 1.6e-21 76.1 0.2 3.9e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e WLM PF08325.5 ETS61474.1 - 0.027 14.3 1.2 0.049 13.5 0.8 1.4 1 0 0 1 1 1 0 WLM domain zf-CHCC PF10276.4 ETS61475.1 - 3.4e-17 61.9 1.3 5.1e-17 61.4 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 ETS61475.1 - 0.00079 19.1 0.0 0.00098 18.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Aminotran_5 PF00266.14 ETS61476.1 - 5.5e-89 298.4 0.0 1.3e-88 297.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Ribosomal_S24e PF01282.14 ETS61476.1 - 0.051 13.3 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S24e DUF2423 PF10338.4 ETS61476.1 - 0.66 9.9 4.0 1.9 8.5 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) DUF1212 PF06738.7 ETS61477.1 - 2e-43 148.0 0.6 2e-43 148.0 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 ETS61477.1 - 3e-17 62.7 4.5 3e-17 62.7 3.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Peptidase_M43 PF05572.8 ETS61478.1 - 4.1e-17 62.1 0.1 6.6e-17 61.5 0.0 1.4 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 ETS61478.1 - 2.3e-08 34.2 1.4 3.1e-08 33.7 0.8 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 ETS61478.1 - 1.1e-06 28.8 0.9 1.5e-06 28.3 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ETS61478.1 - 3.2e-06 27.6 0.9 5.7e-06 26.8 0.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 ETS61478.1 - 0.00037 20.0 2.9 0.0011 18.4 2.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 ETS61478.1 - 0.015 14.5 0.3 0.029 13.7 0.2 1.4 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 ETS61478.1 - 0.048 12.5 0.1 0.077 11.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 ETS61478.1 - 0.066 12.9 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin Epimerase PF01370.16 ETS61479.1 - 8.4e-26 90.8 0.1 6.1e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS61479.1 - 1.1e-14 53.8 0.0 1.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS61479.1 - 7.5e-13 48.7 0.1 1.6e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 ETS61479.1 - 2e-11 43.3 0.0 3.8e-11 42.4 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ETS61479.1 - 3.4e-10 40.2 0.0 5.5e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS61479.1 - 1.1e-08 34.9 0.1 1.9e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS61479.1 - 2e-08 33.5 0.0 9.4e-07 28.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS61479.1 - 3.2e-06 26.2 0.1 6.7e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 ETS61479.1 - 0.026 13.7 0.1 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Peptidase_S15 PF02129.13 ETS61480.1 - 5e-40 137.6 0.1 1.8e-38 132.5 0.1 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS61480.1 - 2.5e-27 96.1 0.0 3.9e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS61480.1 - 3.2e-07 30.4 0.1 1.8e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS61480.1 - 0.0017 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS61480.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 ETS61480.1 - 0.062 12.5 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1479 PF07350.7 ETS61481.1 - 2e-08 33.1 0.1 0.00088 17.8 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.8 ETS61481.1 - 2.1e-07 31.2 0.0 9.8e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 ETS61482.1 - 2.3e-48 164.7 46.4 2.3e-47 161.4 32.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS61482.1 - 7.2e-21 74.0 18.4 1.1e-20 73.3 12.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS61482.1 - 8.9e-12 44.3 13.0 8.9e-12 44.3 9.0 3.4 3 1 0 4 4 4 2 Sugar (and other) transporter UPF0233 PF06781.7 ETS61482.1 - 0.034 13.7 0.4 0.034 13.7 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Spore_YhaL PF14147.1 ETS61482.1 - 0.095 12.1 0.2 0.33 10.4 0.1 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL OATP PF03137.15 ETS61482.1 - 1.4 6.8 17.8 0.053 11.5 0.5 3.7 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 ETS61483.1 - 4.7e-20 71.5 23.4 4.7e-20 71.5 16.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS61483.1 - 1.5e-10 40.2 19.0 3.8e-10 38.9 13.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter SecE PF00584.15 ETS61483.1 - 0.3 10.7 0.1 0.3 10.7 0.0 4.4 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex DUF2721 PF11026.3 ETS61483.1 - 6.2 6.4 11.9 0.44 10.1 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1680 PF07944.7 ETS61484.1 - 3.3e-106 355.6 0.0 4.1e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Sugar_tr PF00083.19 ETS61485.1 - 2.6e-67 227.3 26.1 3.7e-67 226.8 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS61485.1 - 3.9e-27 94.8 57.9 3.2e-21 75.4 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS61488.1 - 5.7e-75 252.6 22.3 7.2e-75 252.2 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS61488.1 - 1.9e-22 79.4 26.4 7.7e-21 74.1 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 ETS61488.1 - 0.0029 16.2 6.9 0.0043 15.6 4.8 1.2 1 0 0 1 1 1 1 Reduced folate carrier Glyco_hydro_39 PF01229.12 ETS61489.1 - 0.00097 17.6 0.1 0.0013 17.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_31 PF01055.21 ETS61490.1 - 3.8e-121 404.9 0.2 5e-121 404.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS61490.1 - 4.8e-05 23.1 0.4 0.00062 19.5 0.1 2.7 2 1 0 2 2 2 1 Galactose mutarotase-like Sugar_tr PF00083.19 ETS61491.1 - 1.4e-86 290.8 23.6 1.8e-86 290.5 16.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS61491.1 - 2.2e-31 108.8 45.8 7e-25 87.4 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0075 PF03702.9 ETS61492.1 - 7.7e-88 294.8 0.0 8.9e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) DUF768 PF05589.6 ETS61492.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) 3Beta_HSD PF01073.14 ETS61494.1 - 1.2e-16 60.2 0.0 1.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS61494.1 - 4.1e-16 59.1 0.0 7.6e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS61494.1 - 6.3e-14 52.3 0.1 1.7e-13 51.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETS61494.1 - 1.4e-13 50.3 0.0 4.9e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 ETS61494.1 - 8.1e-07 28.5 0.1 1.1e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 ETS61494.1 - 3.7e-05 23.6 0.1 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS61494.1 - 0.0011 17.9 0.0 0.0018 17.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 ETS61494.1 - 0.0033 17.1 0.1 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 ETS61494.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Ribonuc_red_sm PF00268.16 ETS61495.1 - 3e-117 390.6 1.2 3.6e-117 390.3 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Abhydrolase_6 PF12697.2 ETS61496.1 - 3e-10 40.3 1.6 6.3e-09 36.0 0.1 2.7 2 2 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS61496.1 - 2.2e-07 30.7 0.0 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS61496.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 ETS61496.1 - 0.00038 20.2 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 ETS61496.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 ETS61496.1 - 0.063 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold TPR_1 PF00515.23 ETS61496.1 - 0.067 12.8 0.6 8.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldolase_II PF00596.16 ETS61497.1 - 8.3e-24 84.1 0.0 1.2e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3533 PF12051.3 ETS61498.1 - 7.3e-100 334.3 16.5 8.7e-100 334.1 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) UPF0233 PF06781.7 ETS61498.1 - 0.096 12.3 2.5 14 5.4 0.0 3.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Aa_trans PF01490.13 ETS61499.1 - 0.00028 19.4 8.5 0.007 14.8 5.4 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein zf-RING_2 PF13639.1 ETS61500.1 - 5.4e-10 38.9 17.7 6e-08 32.3 1.2 3.4 2 2 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 ETS61500.1 - 3.1e-06 26.7 8.8 3.7e-05 23.2 0.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS61500.1 - 8.4e-06 25.8 6.9 8e-05 22.6 0.1 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETS61500.1 - 0.00077 19.4 12.5 0.0022 18.0 0.9 3.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS61500.1 - 0.0019 18.0 5.5 0.0027 17.4 0.3 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 ETS61500.1 - 0.0022 17.5 10.8 0.053 13.1 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS61500.1 - 0.0026 17.4 8.9 0.017 14.8 0.2 3.2 3 0 0 3 3 3 1 zinc-RING finger domain RINGv PF12906.2 ETS61500.1 - 0.51 10.4 8.9 0.077 13.0 1.5 2.6 2 0 0 2 2 2 0 RING-variant domain UPF0547 PF10571.4 ETS61500.1 - 1.3 8.7 4.4 2.3 7.9 0.2 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 GILT PF03227.11 ETS61502.1 - 5.9e-07 29.3 0.2 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) 4HBT PF03061.17 ETS61503.1 - 2.9e-07 30.5 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily DUF3543 PF12063.3 ETS61504.1 - 2.7e-57 193.7 0.1 4.2e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 ETS61504.1 - 3.8e-56 190.1 0.0 5.2e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61504.1 - 1.6e-40 138.8 0.0 4e-40 137.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS61504.1 - 0.013 14.5 0.0 0.038 12.9 0.0 1.8 1 1 0 1 1 1 0 Kinase-like WD40 PF00400.27 ETS61505.1 - 1.6e-38 129.2 21.1 4.8e-10 38.9 0.2 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF3312 PF11768.3 ETS61505.1 - 0.00063 18.0 0.1 0.0021 16.3 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3312) IKI3 PF04762.7 ETS61505.1 - 0.006 14.4 0.1 0.0078 14.0 0.1 1.3 1 0 0 1 1 1 1 IKI3 family PQQ_3 PF13570.1 ETS61505.1 - 0.052 13.8 11.9 0.19 12.0 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain MutS_V PF00488.16 ETS61506.1 - 3.1e-57 193.6 0.0 5.2e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS61506.1 - 3.3e-29 102.1 4.8 3.3e-29 102.1 3.3 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 ETS61506.1 - 9.9e-05 22.4 0.0 0.00028 20.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 ETS61506.1 - 0.00023 21.2 0.2 0.00042 20.4 0.2 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 ETS61506.1 - 0.0026 17.2 0.0 0.0079 15.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS61506.1 - 0.018 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS61506.1 - 0.02 14.3 0.0 0.093 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS61506.1 - 0.048 13.0 0.0 0.28 10.5 0.0 2.2 2 2 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 ETS61506.1 - 0.062 13.4 0.1 0.42 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 ETS61506.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 ETS61506.1 - 0.079 12.9 0.1 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETS61506.1 - 0.084 12.5 0.1 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_L7Ae PF01248.21 ETS61507.1 - 2.6e-27 94.1 0.1 3.2e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 ETS61507.1 - 0.0049 16.7 0.0 0.0059 16.4 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 ETS61507.1 - 0.04 13.6 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain HTH_Crp_2 PF13545.1 ETS61507.1 - 0.045 13.5 0.0 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Phenol_Hydrox PF02332.13 ETS61507.1 - 0.062 12.5 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase DUF218 PF02698.12 ETS61508.1 - 0.051 13.0 0.3 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 DUF218 domain Arrestin_N PF00339.24 ETS61509.1 - 1.8e-05 24.6 0.0 3.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain UPF0203 PF05254.7 ETS61510.1 - 8.1e-16 57.6 1.5 1.9e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) P33MONOX PF15302.1 ETS61510.1 - 0.00029 20.5 0.9 0.00034 20.3 0.7 1.1 1 0 0 1 1 1 1 P33 mono-oxygenase UCR_hinge PF02320.11 ETS61510.1 - 0.0018 18.1 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 ETS61510.1 - 0.11 12.5 0.8 9.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 ETS61510.1 - 0.13 12.3 1.3 0.57 10.2 0.3 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Herpes_capsid PF06112.6 ETS61510.1 - 6.4 6.8 17.9 0.12 12.3 2.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SR-25 PF10500.4 ETS61510.1 - 7.9 5.8 17.7 49 3.2 12.2 2.2 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRK PF00485.13 ETS61511.1 - 1.6e-07 31.0 0.0 3.9e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 ETS61511.1 - 7.3e-05 23.0 0.3 0.00061 20.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS61511.1 - 0.00081 20.2 0.3 0.0028 18.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS61511.1 - 0.0086 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 ETS61511.1 - 0.02 13.8 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 ETS61511.1 - 0.18 11.6 0.7 1.5 8.7 0.4 2.1 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 ETS61512.1 - 5.5e-67 224.3 0.0 6.2e-67 224.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 ETS61512.1 - 6.9e-10 38.1 0.1 1.7e-06 27.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 ETS61512.1 - 1.5e-09 37.3 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 ETS61512.1 - 7.4e-09 36.1 0.0 1e-08 35.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 ETS61512.1 - 1.1e-08 34.6 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 ETS61512.1 - 1.5e-07 31.3 0.0 4.9e-07 29.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETS61512.1 - 9.4e-06 24.9 0.0 1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS61512.1 - 0.0054 16.1 0.0 0.17 11.2 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 ETS61512.1 - 0.012 15.1 0.0 0.05 13.1 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 ETS61512.1 - 0.033 13.4 0.0 0.076 12.2 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) IF4E PF01652.13 ETS61513.1 - 1.3e-50 171.1 0.0 1.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Bromo_TP PF07524.8 ETS61514.1 - 8.9e-07 28.5 0.1 1.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 ETS61514.1 - 0.0054 16.7 7.4 0.017 15.1 1.8 2.7 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Rhodanese PF00581.15 ETS61515.1 - 9.9e-09 35.5 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ECH PF00378.15 ETS61516.1 - 1.5e-34 119.2 1.1 3.6e-34 117.9 0.7 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family adh_short_C2 PF13561.1 ETS61519.1 - 1e-32 113.8 0.0 1.2e-32 113.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS61519.1 - 8.5e-12 45.3 0.6 1.1e-11 44.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS61519.1 - 0.0027 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 ETS61519.1 - 0.0045 16.0 0.1 0.0085 15.1 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 ETS61519.1 - 0.012 15.3 4.4 0.022 14.5 2.7 1.7 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase IlvN PF07991.7 ETS61519.1 - 0.025 13.9 0.1 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 ETS61519.1 - 0.058 13.3 0.3 0.12 12.3 0.2 1.7 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 ETS61519.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.20 ETS61520.1 - 7.1e-61 205.6 0.0 4.5e-35 121.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61520.1 - 1.2e-20 73.6 0.0 1.3e-18 67.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Elong_Iki1 PF10483.4 ETS61520.1 - 1.4e-13 50.8 0.0 8e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Elongator subunit Iki1 Kdo PF06293.9 ETS61520.1 - 0.00089 18.3 0.1 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.16 ETS61521.1 - 6.5e-10 38.8 8.4 2.1e-09 37.2 5.8 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS61521.1 - 4.8e-09 35.9 6.4 7.1e-09 35.3 4.0 1.6 1 1 0 1 1 1 1 Basic region leucine zipper Spc7 PF08317.6 ETS61521.1 - 0.0013 17.4 1.2 0.0019 16.9 0.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Herpes_BLRF2 PF05812.7 ETS61521.1 - 0.016 14.9 0.2 0.016 14.9 0.1 2.5 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein NUDE_C PF04880.8 ETS61521.1 - 0.031 14.6 0.0 0.031 14.6 0.0 2.6 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region DUF972 PF06156.8 ETS61521.1 - 0.035 14.4 0.2 0.083 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phlebovirus_NSM PF07246.6 ETS61521.1 - 0.043 12.9 2.3 0.061 12.4 1.6 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Herpes_UL6 PF01763.11 ETS61521.1 - 0.11 10.6 0.5 0.15 10.1 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_Maf PF03131.12 ETS61521.1 - 0.14 12.4 5.2 0.33 11.2 3.6 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.13 ETS61521.1 - 0.18 11.7 0.9 0.58 10.1 0.2 2.2 1 1 0 1 1 1 0 TSC-22/dip/bun family HAP1_N PF04849.8 ETS61521.1 - 0.21 10.5 6.1 0.41 9.5 4.2 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Atg14 PF10186.4 ETS61521.1 - 0.25 10.2 5.5 0.38 9.6 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 ETS61521.1 - 2.6 6.2 6.8 3.5 5.7 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DivIC PF04977.10 ETS61521.1 - 5.7 6.4 8.2 0.29 10.6 1.8 1.7 2 0 0 2 2 2 0 Septum formation initiator TFIID-31kDa PF02291.10 ETS61522.1 - 1.6e-40 137.8 0.2 2.9e-40 137.0 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 ETS61522.1 - 0.0066 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated APC_CDC26 PF10471.4 ETS61522.1 - 0.065 13.9 5.4 0.14 12.9 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Ribosomal_S14 PF00253.16 ETS61523.1 - 3e-21 74.5 0.4 1.4e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e SIP1 PF04938.7 ETS61524.1 - 2.4e-15 56.5 0.0 4.3e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) MFS_1 PF07690.11 ETS61526.1 - 1.6e-29 102.7 34.5 1e-26 93.5 10.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS61526.1 - 4.3e-16 58.5 2.3 4.3e-16 58.5 1.6 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter COX15-CtaA PF02628.10 ETS61527.1 - 1e-78 264.2 17.0 2.2e-78 263.1 11.8 1.6 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_L19 PF01245.15 ETS61528.1 - 5.3e-27 93.8 0.3 7.6e-27 93.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Not3 PF04065.10 ETS61529.1 - 5.6e-96 320.3 23.6 9.4e-96 319.5 16.4 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 ETS61529.1 - 1.7e-45 154.2 10.4 5.1e-45 152.6 7.2 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 ETS61529.1 - 0.0027 17.2 2.7 0.008 15.7 1.9 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 ETS61529.1 - 0.83 9.6 8.0 0.093 12.6 1.2 2.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Ribonuclease_3 PF00636.21 ETS61531.1 - 3.2e-30 104.9 0.0 3e-18 66.3 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 ETS61531.1 - 5.1e-19 68.5 0.1 6.7e-10 39.0 0.0 3.6 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 ETS61531.1 - 2e-15 56.3 0.0 4.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 ETS61531.1 - 4.7e-11 42.3 0.1 1.1e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS61531.1 - 9.4e-09 34.9 0.0 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS61531.1 - 4.1e-06 26.7 0.0 1.5e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 ETS61531.1 - 0.0021 18.5 0.0 0.0044 17.5 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif cwf21 PF08312.7 ETS61532.1 - 1.3e-15 57.0 9.6 1.3e-15 57.0 6.7 3.0 3 1 0 3 3 3 1 cwf21 domain MIP-T3 PF10243.4 ETS61532.1 - 4.2 5.7 52.7 5.8 5.2 36.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WLM PF08325.5 ETS61533.1 - 6.5e-26 91.3 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 ETS61533.1 - 0.0037 16.6 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF45 PF01863.12 ETS61533.1 - 0.0075 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Paralemmin PF03285.10 ETS61533.1 - 0.027 13.9 3.2 1.3 8.3 1.1 2.2 2 0 0 2 2 2 0 Paralemmin Acyl-CoA_dh_1 PF00441.19 ETS61534.1 - 1.9e-26 92.9 4.5 2.8e-26 92.4 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS61534.1 - 9.3e-15 53.8 0.1 3.2e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS61534.1 - 1.7e-11 44.4 4.6 3.1e-11 43.6 3.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS61534.1 - 1.3e-09 38.6 0.0 3.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain MCM PF00493.18 ETS61535.1 - 3.2e-133 443.6 0.0 7.5e-133 442.4 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family SLAC1 PF03595.12 ETS61535.1 - 9.7e-78 261.0 43.8 1.3e-77 260.6 30.3 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel MCM_N PF14551.1 ETS61535.1 - 6e-27 94.5 0.0 1.6e-26 93.1 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 ETS61535.1 - 1.3e-07 31.4 0.0 6e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS61535.1 - 8.5e-07 28.3 0.0 3.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Ras PF00071.17 ETS61536.1 - 6.9e-43 145.8 0.2 9.4e-41 138.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETS61536.1 - 1.1e-19 71.0 0.1 2.1e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61536.1 - 4.2e-11 42.3 0.1 6.7e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS61536.1 - 0.00034 20.5 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETS61536.1 - 0.0021 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETS61536.1 - 0.0024 17.1 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 ETS61536.1 - 0.12 11.5 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 ETS61536.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AhpC-TSA PF00578.16 ETS61537.1 - 9.9e-33 112.4 0.0 1.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS61537.1 - 4e-11 42.6 0.0 4.9e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 ETS61537.1 - 4e-10 39.1 0.0 6.8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 ETS61537.1 - 0.046 13.6 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme AMMECR1 PF01871.12 ETS61538.1 - 1e-38 132.1 0.0 9.2e-29 99.7 0.0 2.1 2 0 0 2 2 2 2 AMMECR1 TspO_MBR PF03073.10 ETS61539.1 - 1.4e-47 160.9 7.8 1.6e-47 160.7 5.4 1.0 1 0 0 1 1 1 1 TspO/MBR family SBDS PF01172.13 ETS61541.1 - 8.9e-15 54.2 0.1 1.1e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNF5 PF04855.7 ETS61542.1 - 4.8e-67 225.9 2.1 1.5e-64 217.8 0.3 2.2 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 tRNA-synt_2 PF00152.15 ETS61543.1 - 6.2e-102 340.8 0.0 2.9e-50 170.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS61543.1 - 1.3e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 ETS61543.1 - 0.001 18.7 0.0 0.59 9.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 ETS61543.1 - 0.12 11.5 0.1 1.2 8.2 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) LIM PF00412.17 ETS61544.1 - 3.7e-28 97.3 35.0 1.7e-12 47.2 2.2 5.1 4 1 0 4 4 4 4 LIM domain LEA_3 PF03242.8 ETS61545.1 - 4.6 7.5 8.3 0.79 9.9 0.9 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein ketoacyl-synt PF00109.21 ETS61546.1 - 5.3e-58 196.4 0.2 1.1e-57 195.4 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.15 ETS61546.1 - 1.5e-20 74.4 0.0 6.8e-20 72.2 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 ETS61546.1 - 1.2e-18 67.1 4.5 4e-09 36.5 0.8 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.17 ETS61546.1 - 4e-13 49.2 1.0 1.1e-12 47.8 0.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Abhydrolase_5 PF12695.2 ETS61546.1 - 0.0024 17.6 1.9 0.015 15.0 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Zn_clus PF00172.13 ETS61547.1 - 0.026 14.4 11.3 0.31 10.9 7.8 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MRP_L53 PF10780.4 ETS61548.1 - 8.7 6.4 6.0 4.9 7.1 1.4 2.6 2 2 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Ndc1_Nup PF09531.5 ETS61549.1 - 1.1e-66 225.5 1.6 1.3e-66 225.2 1.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Pertus-S4-tox PF09275.5 ETS61549.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Pertussis toxin S4 subunit PTE PF02126.13 ETS61549.1 - 0.2 10.6 0.5 0.91 8.4 0.2 1.9 2 0 0 2 2 2 0 Phosphotriesterase family Sod_Fe_C PF02777.13 ETS61550.1 - 4.6e-20 71.4 0.1 1e-08 34.9 0.1 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DUF2583 PF10762.4 ETS61550.1 - 0.1 12.7 0.1 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) ketoacyl-synt PF00109.21 ETS61551.1 - 5e-47 160.5 0.0 1.1e-46 159.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS61551.1 - 2.6e-42 145.3 0.0 5.1e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 ETS61551.1 - 8.8e-29 99.7 1.7 1.4e-28 99.0 0.1 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 ETS61551.1 - 2.2e-19 70.6 0.0 7e-19 68.9 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 ETS61551.1 - 9.1e-17 61.1 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 ETS61551.1 - 1.2e-05 25.1 0.1 0.036 13.8 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family SNARE_assoc PF09335.6 ETS61553.1 - 7.5e-14 52.0 4.9 7.5e-14 52.0 3.4 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein FSH1 PF03959.8 ETS61553.1 - 1.2e-12 47.7 0.0 2.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) UPF0160 PF03690.8 ETS61554.1 - 9.4e-124 412.9 0.0 1.2e-123 412.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) cobW PF02492.14 ETS61554.1 - 5.8e-35 120.3 0.0 1e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 ETS61554.1 - 6.5e-05 23.7 0.5 0.03 15.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 ETS61554.1 - 0.00044 19.1 2.3 0.0026 16.5 1.6 2.0 1 1 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 ETS61554.1 - 0.0047 16.9 1.6 0.63 9.9 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 ETS61554.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 ETS61554.1 - 0.046 13.0 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.7 ETS61554.1 - 0.076 12.6 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 ETS61554.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETS61554.1 - 0.096 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 ETS61554.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Arch_ATPase PF01637.13 ETS61554.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase APH PF01636.18 ETS61555.1 - 4.3e-35 121.5 0.0 6.2e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS61555.1 - 3.4e-05 23.1 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 ETS61555.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DASH_Hsk3 PF08227.6 ETS61555.1 - 0.015 15.4 0.0 0.057 13.6 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like BTB PF00651.26 ETS61556.1 - 2.6e-07 30.6 0.0 2.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Acyltransferase PF01553.16 ETS61557.1 - 1.6e-34 118.1 0.0 2.6e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Plant_NMP1 PF06694.6 ETS61557.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) O-antigen_lig PF13425.1 ETS61557.1 - 0.22 11.5 4.3 0.45 10.4 3.0 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein L27_2 PF09045.5 ETS61557.1 - 0.25 10.8 1.8 8.6 5.9 0.2 2.8 2 1 1 3 3 3 0 L27_2 Kinesin PF00225.18 ETS61558.1 - 2.9e-53 180.7 0.0 5e-53 179.9 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain His_Phos_2 PF00328.17 ETS61559.1 - 3.3e-29 102.3 0.0 4.2e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MoCF_biosynth PF00994.19 ETS61560.1 - 1.8e-33 115.0 0.0 2.8e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain AAA_2 PF07724.9 ETS61561.1 - 1.2e-46 158.7 0.0 4.9e-45 153.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 ETS61561.1 - 3.7e-26 91.8 0.0 5.6e-16 58.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 ETS61561.1 - 2.7e-18 65.6 0.2 1.1e-17 63.6 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 ETS61561.1 - 7e-15 54.7 6.8 3e-07 30.2 0.3 4.0 3 0 0 3 3 3 2 Clp amino terminal domain AAA_5 PF07728.9 ETS61561.1 - 2.5e-14 53.1 0.0 9.7e-09 35.0 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS61561.1 - 9.1e-13 48.5 6.9 1.7e-05 24.9 0.0 5.2 3 3 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.21 ETS61561.1 - 1.7e-09 37.3 0.0 1.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 ETS61561.1 - 2.4e-08 34.2 0.1 0.0058 16.7 0.0 4.5 3 2 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 ETS61561.1 - 2.1e-07 30.2 0.1 0.0012 17.9 0.0 4.1 3 1 0 4 4 4 1 Zeta toxin Mg_chelatase PF01078.16 ETS61561.1 - 0.00013 21.2 0.2 0.56 9.3 0.0 3.4 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 ETS61561.1 - 0.00036 19.9 0.0 0.032 13.6 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 ETS61561.1 - 0.00039 20.7 0.2 0.9 9.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 ETS61561.1 - 0.00057 20.7 7.1 2.5 8.9 0.0 4.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS61561.1 - 0.00075 19.3 2.1 0.9 9.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 ETS61561.1 - 0.00077 19.1 0.1 0.08 12.7 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain TrwB_AAD_bind PF10412.4 ETS61561.1 - 0.00081 18.1 0.0 1.9 7.0 0.0 3.1 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 ETS61561.1 - 0.0021 17.4 0.1 1.4 8.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS61561.1 - 0.0021 17.5 5.7 2.1 7.7 0.1 4.3 4 1 0 5 5 5 2 AAA-like domain RNA_helicase PF00910.17 ETS61561.1 - 0.0023 18.0 0.1 5 7.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.1 ETS61561.1 - 0.0027 17.6 3.3 0.22 11.4 0.0 3.4 3 1 0 3 3 2 1 AAA domain Torsin PF06309.6 ETS61561.1 - 0.0031 17.4 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 Torsin NACHT PF05729.7 ETS61561.1 - 0.0033 17.1 0.0 2.1 7.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 ETS61561.1 - 0.0055 16.2 0.1 4 7.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETS61561.1 - 0.015 14.5 0.0 0.83 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 ETS61561.1 - 0.032 13.8 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 ETS61561.1 - 0.032 13.9 0.0 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 ETS61561.1 - 0.034 13.6 0.0 13 5.2 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 ETS61561.1 - 0.036 13.4 0.4 0.87 8.9 0.0 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_3 PF07726.6 ETS61561.1 - 0.04 13.5 0.0 7.6 6.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETS61561.1 - 0.042 14.1 0.4 13 6.0 0.0 3.3 3 0 0 3 3 3 0 ABC transporter Arch_ATPase PF01637.13 ETS61561.1 - 0.042 13.5 4.7 0.23 11.1 0.0 3.9 4 1 0 5 5 5 0 Archaeal ATPase AAA_24 PF13479.1 ETS61561.1 - 0.06 12.9 0.0 14 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain EMP24_GP25L PF01105.19 ETS61561.1 - 0.28 10.8 2.5 0.3 10.7 0.6 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Cytochrom_B561 PF03188.11 ETS61562.1 - 1.9e-08 34.1 10.3 4.6e-08 32.9 7.1 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 ETS61562.1 - 1.5e-06 28.1 1.9 3e-06 27.1 1.3 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 ETS61562.1 - 3.8e-06 26.4 2.4 3.8e-06 26.4 1.7 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF4079 PF13301.1 ETS61562.1 - 0.00012 22.1 5.6 0.00012 22.1 3.9 2.8 3 1 1 4 4 4 1 Protein of unknown function (DUF4079) Polysacc_synt_3 PF13440.1 ETS61562.1 - 0.005 16.3 8.0 0.38 10.1 0.1 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein E1-E2_ATPase PF00122.15 ETS61563.1 - 8.1e-53 178.8 3.6 1.7e-52 177.7 2.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS61563.1 - 1.8e-40 138.4 2.9 1.8e-40 138.4 2.0 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS61563.1 - 8.7e-30 104.7 0.0 7e-29 101.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS61563.1 - 2.8e-16 59.2 0.0 5.7e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS61563.1 - 1.2e-14 54.9 0.3 4e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS61563.1 - 3e-12 45.8 0.2 7.6e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS61563.1 - 0.00087 18.9 0.8 0.0016 18.0 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_C32 PF05411.7 ETS61563.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DUF2231 PF09990.4 ETS61563.1 - 1.2 9.5 7.8 0.48 10.7 0.3 3.5 4 0 0 4 4 4 0 Predicted membrane protein (DUF2231) SUR7 PF06687.7 ETS61563.1 - 5 6.6 10.6 0.5 9.8 0.4 3.1 3 0 0 3 3 3 0 SUR7/PalI family Orthoreo_P10 PF07204.6 ETS61564.1 - 0.037 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.1 ETS61564.1 - 0.042 14.2 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 ETS61564.1 - 7.4 6.7 12.3 2.8e+02 1.5 8.5 2.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator CDK2AP PF09806.4 ETS61565.1 - 0.043 14.0 0.1 0.046 13.9 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TALPID3 PF15324.1 ETS61565.1 - 0.059 10.7 1.7 0.072 10.4 1.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target zf-Tim10_DDP PF02953.10 ETS61567.1 - 3.1e-19 68.0 3.2 4.8e-19 67.4 2.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DFF-C PF09033.5 ETS61567.1 - 0.09 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain eIF-6 PF01912.13 ETS61568.1 - 4.4e-83 277.2 0.3 6.5e-83 276.7 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family EnY2 PF10163.4 ETS61570.1 - 1e-20 73.4 0.0 1.2e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 RecO_C PF02565.10 ETS61570.1 - 0.026 14.3 0.2 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Recombination protein O C terminal DUF668 PF05003.7 ETS61570.1 - 0.087 13.0 0.1 7.6 6.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF668) RNA_Me_trans PF04252.8 ETS61571.1 - 4.8e-22 78.3 0.0 1.7e-19 70.0 0.0 3.0 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase GTP_cyclohydroI PF01227.17 ETS61572.1 - 6.9e-73 243.7 0.2 9.1e-73 243.3 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 ETS61572.1 - 0.0031 17.4 0.0 0.0079 16.1 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 ETS61572.1 - 0.016 15.0 0.1 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ribosomal_S25 PF03297.10 ETS61573.1 - 1.1e-41 141.1 0.3 1.6e-41 140.5 0.2 1.4 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 ETS61573.1 - 0.065 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PulS_OutS PF09691.5 ETS61573.1 - 0.098 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) Mt_ATP-synt_D PF05873.7 ETS61574.1 - 1.6e-12 47.3 1.6 1.9e-12 47.1 1.1 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GAS PF13851.1 ETS61574.1 - 0.0033 16.6 4.9 0.0045 16.2 3.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF2408 PF10303.4 ETS61574.1 - 0.027 14.5 4.7 0.099 12.7 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF2570 PF10828.3 ETS61574.1 - 0.063 12.8 9.3 0.23 11.1 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Peptidase_M17_N PF02789.12 ETS61574.1 - 0.067 12.9 0.7 0.17 11.6 0.0 1.9 1 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain AAA_13 PF13166.1 ETS61574.1 - 0.073 11.5 4.6 0.09 11.2 3.2 1.1 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.2 ETS61574.1 - 0.088 12.1 12.1 0.52 9.5 1.5 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Dor1 PF04124.7 ETS61574.1 - 0.098 11.1 4.9 0.13 10.7 3.4 1.1 1 0 0 1 1 1 0 Dor1-like family Phage_GP20 PF06810.6 ETS61574.1 - 0.11 11.8 6.0 0.32 10.4 0.6 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 AHS1 PF02682.11 ETS61574.1 - 0.12 11.8 1.5 0.15 11.4 1.0 1.2 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Prominin PF05478.6 ETS61574.1 - 0.18 9.2 1.6 0.2 9.1 1.1 1.0 1 0 0 1 1 1 0 Prominin DUF948 PF06103.6 ETS61574.1 - 0.2 11.5 3.9 2.6 7.9 0.2 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 ETS61574.1 - 0.4 8.4 4.5 1 7.1 2.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 ETS61574.1 - 0.44 10.3 9.9 2.4 7.9 6.8 2.1 1 1 0 1 1 1 0 Prefoldin subunit Snf7 PF03357.16 ETS61574.1 - 0.8 9.0 8.3 0.13 11.6 1.4 2.2 1 1 1 2 2 2 0 Snf7 IncA PF04156.9 ETS61574.1 - 1.2 8.7 7.6 3.8 7.0 5.3 1.7 1 1 0 1 1 1 0 IncA protein MbeB_N PF04837.7 ETS61574.1 - 1.4 9.0 5.9 0.58 10.2 0.8 2.5 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DivIC PF04977.10 ETS61574.1 - 1.9 7.9 11.2 0.65 9.5 0.6 2.4 1 1 0 2 2 2 0 Septum formation initiator MxiH PF09392.5 ETS61574.1 - 2.5 8.7 5.6 1.3e+02 3.1 3.8 2.4 1 1 0 1 1 1 0 Type III secretion needle MxiH like FlxA PF14282.1 ETS61574.1 - 2.5 8.1 12.9 8 6.4 2.1 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF2681 PF10883.3 ETS61574.1 - 6 7.1 8.2 3.2e+02 1.6 5.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) cNMP_binding PF00027.24 ETS61575.1 - 4.6e-42 141.7 0.0 1.2e-20 73.0 0.0 2.6 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 ETS61575.1 - 4e-15 54.9 0.3 7.8e-15 54.0 0.2 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.6 ETS61575.1 - 0.07 12.6 0.5 0.56 9.7 0.1 2.4 3 0 0 3 3 3 0 Cupin domain Abhydrolase_6 PF12697.2 ETS61576.1 - 5.8e-17 62.3 1.9 1.1e-16 61.4 1.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS61576.1 - 1.4e-05 24.9 0.0 3.8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS61576.1 - 0.0002 20.8 0.0 0.00062 19.2 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.15 ETS61576.1 - 0.0026 17.3 0.0 0.068 12.7 0.0 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aft1_HRA PF11786.3 ETS61577.1 - 7.4e-17 61.3 11.6 7.4e-17 61.3 8.0 3.2 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.16 ETS61577.1 - 5.3e-10 39.1 6.5 9.8e-10 38.2 4.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS61577.1 - 1.4e-06 28.0 8.7 3.6e-06 26.7 6.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 ETS61577.1 - 0.00073 20.0 1.4 0.00073 20.0 1.0 4.2 3 1 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.12 ETS61577.1 - 0.00098 19.3 5.6 0.0021 18.3 3.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Shugoshin_N PF07558.6 ETS61577.1 - 0.053 13.2 0.3 0.097 12.3 0.2 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF904 PF06005.7 ETS61577.1 - 0.12 12.6 0.4 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 ETS61577.1 - 0.15 11.7 0.5 0.36 10.5 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Sugar_tr PF00083.19 ETS61578.1 - 1.4e-99 333.7 21.8 1.7e-99 333.4 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS61578.1 - 6.7e-33 113.8 44.3 1.3e-27 96.4 12.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS61578.1 - 5.6e-05 21.7 0.6 5.6e-05 21.7 0.4 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein DUF1228 PF06779.9 ETS61578.1 - 0.0016 18.4 5.9 0.09 12.8 0.3 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1228) DUF697 PF05128.7 ETS61578.1 - 0.051 13.0 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF697) TRI12 PF06609.8 ETS61578.1 - 0.1 10.7 9.6 0.023 12.8 0.7 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 ETS61578.1 - 0.98 7.4 8.6 0.34 8.9 1.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Transketolase_N PF00456.16 ETS61579.1 - 4.7e-117 390.5 0.6 7.6e-117 389.8 0.4 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 ETS61579.1 - 1.3e-42 145.3 0.1 3.4e-42 143.9 0.1 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 ETS61579.1 - 3.4e-06 26.1 0.0 4.4e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 ETS61579.1 - 5.4e-06 26.3 0.0 1.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 ETS61579.1 - 8.1e-05 21.4 0.1 0.00013 20.7 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 ETS61579.1 - 0.0043 16.6 0.9 0.021 14.3 0.6 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2280 PF10045.4 ETS61579.1 - 0.16 11.8 0.7 0.35 10.8 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) adh_short PF00106.20 ETS61580.1 - 6.1e-27 94.5 5.4 9.3e-27 93.9 3.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS61580.1 - 3.9e-25 89.0 0.2 5.7e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS61580.1 - 3.3e-15 56.2 2.8 5.1e-15 55.6 1.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS61580.1 - 0.00061 19.2 0.5 0.0016 17.9 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS61580.1 - 0.00065 18.4 0.0 0.0016 17.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS61580.1 - 0.0058 15.5 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 ETS61580.1 - 0.057 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_26 PF13659.1 ETS61580.1 - 0.11 12.5 1.2 0.55 10.2 0.8 2.1 1 1 0 1 1 1 0 Methyltransferase domain Cu-oxidase_3 PF07732.10 ETS61581.1 - 8.7e-34 115.7 3.7 2e-20 72.6 0.2 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS61581.1 - 7e-33 113.7 0.0 4.7e-30 104.6 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS61581.1 - 2.2e-29 101.7 3.0 2.2e-29 101.7 2.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Phosphoesterase PF04185.9 ETS61582.1 - 8.7e-75 252.2 2.9 1.2e-74 251.8 2.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family DAO PF01266.19 ETS61583.1 - 3.9e-39 134.5 3.5 4.6e-39 134.3 2.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS61583.1 - 5.8e-05 22.1 0.6 0.02 13.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS61583.1 - 9.7e-05 22.5 0.0 0.00035 20.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS61583.1 - 0.0014 18.4 1.4 0.32 10.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS61583.1 - 0.0017 18.2 0.2 0.11 12.4 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 ETS61583.1 - 0.0019 17.2 0.2 0.0031 16.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ThiF PF00899.16 ETS61583.1 - 0.0036 17.1 0.1 0.0074 16.1 0.1 1.4 1 0 0 1 1 1 1 ThiF family Ldh_1_N PF00056.18 ETS61583.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 ETS61583.1 - 0.031 14.3 0.1 0.075 13.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 ETS61583.1 - 0.032 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 ETS61583.1 - 0.05 12.6 0.2 0.081 11.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 ETS61583.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 ETS61583.1 - 0.099 11.2 0.1 5.4 5.5 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 ETS61583.1 - 0.14 12.5 0.2 0.8 10.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transaldolase PF00923.14 ETS61584.1 - 2.9e-28 98.8 0.0 4.2e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 Transaldolase Abhydrolase_6 PF12697.2 ETS61585.1 - 2.6e-19 70.0 3.7 4.3e-19 69.2 2.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS61585.1 - 6.1e-12 45.5 0.4 1.1e-11 44.6 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS61585.1 - 2.9e-05 23.7 0.9 0.001 18.6 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 ETS61585.1 - 3.1e-05 23.0 0.0 0.00083 18.3 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 ETS61585.1 - 4e-05 22.9 0.1 0.0003 20.0 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Cupin_3 PF05899.7 ETS61585.1 - 0.00021 20.5 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_2 PF07883.6 ETS61585.1 - 0.00035 19.9 0.3 0.21 11.1 0.0 3.1 3 0 0 3 3 3 1 Cupin domain Peptidase_S15 PF02129.13 ETS61585.1 - 0.03 13.7 0.1 0.78 9.1 0.0 2.2 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Tannase PF07519.6 ETS61585.1 - 0.036 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Cupin_8 PF13621.1 ETS61585.1 - 0.077 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Cupin-like domain PMI_typeI PF01238.16 ETS61585.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphomannose isomerase type I Peptidase_M28 PF04389.12 ETS61586.1 - 8.8e-36 123.3 0.1 1.7e-35 122.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS61586.1 - 1e-12 47.6 0.2 2.3e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 ETS61586.1 - 0.0055 15.5 0.1 0.084 11.6 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF3425 PF11905.3 ETS61587.1 - 6.5e-14 51.9 0.1 1.6e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS61587.1 - 0.00064 19.6 10.8 0.0011 18.8 7.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS61587.1 - 0.0098 15.6 11.7 0.016 14.9 8.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 ETS61587.1 - 0.013 15.7 11.8 0.024 14.9 8.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DJ-1_PfpI PF01965.19 ETS61588.1 - 1.6e-12 47.0 0.0 3.5e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family RVT_1 PF00078.22 ETS61589.1 - 4.9e-09 35.8 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4363 PF14276.1 ETS61589.1 - 0.062 12.9 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) zf-C3HC4 PF00097.20 ETS61591.1 - 9.3e-09 34.8 9.8 9.3e-09 34.8 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS61591.1 - 5.5e-07 29.3 14.2 9.6e-06 25.3 5.7 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_6 PF14835.1 ETS61591.1 - 7.4e-07 28.8 4.8 7.4e-07 28.8 3.3 2.6 2 1 1 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 ETS61591.1 - 3e-06 27.1 12.2 9.5e-06 25.5 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS61591.1 - 5.9e-06 26.0 12.6 7.5e-06 25.7 6.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 ETS61591.1 - 6.1e-06 25.8 13.8 1.3e-05 24.7 6.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.22 ETS61591.1 - 7.5e-05 22.1 0.1 7.5e-05 22.1 0.1 2.2 3 0 0 3 3 3 1 SAP domain zf-Apc11 PF12861.2 ETS61591.1 - 0.00087 19.0 6.6 0.0017 18.1 2.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 ETS61591.1 - 0.0025 17.4 13.3 0.009 15.6 6.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.1 ETS61591.1 - 0.0039 16.8 0.1 0.0039 16.8 0.1 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Nse PF11789.3 ETS61591.1 - 0.0073 15.8 5.2 0.0073 15.8 3.6 2.4 2 1 1 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit Cys_rich_KTR PF14205.1 ETS61591.1 - 0.076 12.4 1.2 5.3 6.5 0.3 2.5 2 0 0 2 2 2 0 Cysteine-rich KTR zf-rbx1 PF12678.2 ETS61591.1 - 0.12 12.4 10.7 0.23 11.5 3.8 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 ETS61591.1 - 0.18 11.5 9.9 0.13 12.0 4.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zinc_ribbon_5 PF13719.1 ETS61591.1 - 0.28 10.7 0.1 0.28 10.7 0.1 3.3 4 0 0 4 4 3 0 zinc-ribbon domain zf-Di19 PF05605.7 ETS61591.1 - 0.32 11.1 6.7 0.25 11.5 0.4 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 ETS61591.1 - 0.37 11.2 0.1 0.37 11.2 0.1 3.9 3 1 0 3 3 2 0 C2H2-type zinc finger zf-MIZ PF02891.15 ETS61591.1 - 1.1 8.7 12.6 4.4 6.8 6.6 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 ETS61591.1 - 1.4 8.6 12.3 1.5 8.4 6.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.11 ETS61591.1 - 3 7.7 8.6 1.6 8.6 4.0 1.9 2 0 0 2 2 1 0 FYVE-type zinc finger LysM PF01476.15 ETS61592.1 - 0.00069 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain FAD_binding_9 PF08021.6 ETS61592.1 - 0.066 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ATP-synt PF00231.14 ETS61594.1 - 7.9e-72 242.0 8.5 9.3e-72 241.8 5.9 1.1 1 0 0 1 1 1 1 ATP synthase Vps16_C PF04840.7 ETS61594.1 - 0.031 13.2 3.9 0.15 10.9 0.2 2.1 2 0 0 2 2 2 0 Vps16, C-terminal region eIF-5_eIF-2B PF01873.12 ETS61595.1 - 3.7e-47 159.0 0.6 5.3e-47 158.5 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF3359 PF11839.3 ETS61595.1 - 0.052 13.8 3.4 0.14 12.4 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) TF_Zn_Ribbon PF08271.7 ETS61595.1 - 0.059 12.6 0.2 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 ETS61595.1 - 0.084 12.8 1.3 0.17 11.8 0.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain ABC_membrane PF00664.18 ETS61597.1 - 3.6e-67 226.6 15.1 2.1e-38 132.3 2.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS61597.1 - 1.7e-60 203.2 0.0 4.6e-30 104.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS61597.1 - 2.4e-13 49.8 0.1 0.00079 18.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS61597.1 - 1.4e-09 38.3 0.0 0.21 11.5 0.0 4.2 3 1 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 ETS61597.1 - 8.7e-09 34.4 0.0 0.0034 16.0 0.0 3.2 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 ETS61597.1 - 1e-08 34.5 1.0 0.0011 18.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS61597.1 - 1.1e-08 35.8 0.0 0.0038 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS61597.1 - 2e-08 33.5 0.0 0.00053 19.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS61597.1 - 7e-07 29.4 0.6 0.0077 16.3 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 ETS61597.1 - 9.3e-07 29.0 0.6 0.047 13.6 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.1 ETS61597.1 - 1.5e-06 28.5 0.0 0.0073 16.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 ETS61597.1 - 7.3e-06 25.5 0.0 0.058 12.7 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 ETS61597.1 - 1.7e-05 25.2 0.3 0.0034 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS61597.1 - 0.00021 21.1 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 ETS61597.1 - 0.00036 20.3 1.6 0.72 9.8 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 ETS61597.1 - 0.0047 16.6 0.1 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ETS61597.1 - 0.0096 15.8 0.0 0.25 11.2 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 ETS61597.1 - 0.01 15.2 3.3 1.6 8.0 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 ETS61597.1 - 0.019 15.0 0.2 5.7 7.1 0.0 3.3 2 1 1 3 3 3 0 RNA helicase MMR_HSR1 PF01926.18 ETS61597.1 - 0.024 14.5 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 ETS61597.1 - 0.024 14.4 0.3 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 ETS61597.1 - 0.031 13.3 0.0 1.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 ETS61597.1 - 0.084 12.6 0.0 2.6 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DLIC PF05783.6 ETS61597.1 - 0.089 11.4 0.0 0.22 10.1 0.0 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.7 ETS61597.1 - 0.22 10.6 0.0 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Guanylate_kin PF00625.16 ETS61597.1 - 0.22 10.9 0.0 0.64 9.4 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase Asp PF00026.18 ETS61598.1 - 3.7e-28 98.6 0.0 4.3e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS61598.1 - 0.00021 21.2 0.1 0.0031 17.4 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 ETS61598.1 - 0.027 14.2 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 ETS61598.1 - 0.037 14.5 0.5 0.24 11.9 0.0 2.4 3 0 0 3 3 3 0 Aspartyl protease Lactamase_B PF00753.22 ETS61599.1 - 1.1e-05 25.2 1.1 1.6e-05 24.6 0.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Sugar_tr PF00083.19 ETS61600.1 - 1.7e-112 376.2 25.2 2.1e-112 375.9 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS61600.1 - 3.6e-24 85.1 39.0 2.2e-17 62.8 6.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RPEL PF02755.10 ETS61601.1 - 7.6e-31 104.5 39.9 1.8e-09 36.6 1.1 5.2 6 0 0 6 6 6 4 RPEL repeat Antimicrobial18 PF08130.6 ETS61601.1 - 0.00043 20.1 0.6 2.2 8.2 0.0 3.2 3 0 0 3 3 3 2 Type A lantibiotic family DnaI_N PF07319.6 ETS61601.1 - 0.0091 16.2 0.2 5.3 7.3 0.0 2.6 1 1 2 3 3 3 2 Primosomal protein DnaI N-terminus DUF1992 PF09350.5 ETS61601.1 - 0.014 15.2 4.7 2.4 8.0 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1992) UvsW PF11637.3 ETS61601.1 - 0.083 12.5 0.3 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 ATP-dependant DNA helicase UvsW DnaB_C PF03796.10 ETS61601.1 - 0.19 10.5 3.3 3 6.6 0.2 2.4 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Phe_tRNA-synt_N PF02912.13 ETS61601.1 - 0.71 9.6 7.0 12 5.7 0.2 3.4 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Alb1 PF09135.6 ETS61601.1 - 0.96 10.0 5.4 10 6.7 0.9 2.5 1 1 2 3 3 3 0 Alb1 ESX-1_EspG PF14011.1 ETS61601.1 - 1.3 8.2 6.4 7.1 5.8 0.3 3.2 1 1 2 3 3 3 0 EspG family NDUF_B12 PF08122.7 ETS61602.1 - 5.3e-22 77.3 0.4 6.2e-22 77.0 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ATP-sulfurylase PF01747.12 ETS61603.1 - 1e-87 292.9 0.2 1.5e-87 292.4 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 ETS61603.1 - 1.3e-54 184.1 0.0 1.9e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 ETS61603.1 - 2.5e-53 179.7 0.0 3.8e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Mito_carr PF00153.22 ETS61604.1 - 1.6e-46 155.9 9.4 7.1e-19 67.3 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med12 PF09497.5 ETS61605.1 - 5e-30 103.2 0.0 5e-29 100.0 0.0 2.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 ETS61605.1 - 0.00087 17.8 0.0 0.0023 16.5 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain tRNA-synt_1 PF00133.17 ETS61606.1 - 1.1e-35 122.7 0.0 1.3e-27 96.0 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ETS61606.1 - 6.1e-18 64.6 0.0 1.8e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 ETS61606.1 - 1.6e-13 50.7 0.0 3.6e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 ETS61606.1 - 1.8e-06 27.2 0.0 5.9e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Peptidase_M14 PF00246.19 ETS61607.1 - 4.4e-62 210.2 0.0 1.3e-61 208.7 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF479 PF04336.7 ETS61607.1 - 0.048 13.7 1.2 0.092 12.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF479 WD40 PF00400.27 ETS61608.1 - 5.1e-87 282.9 12.2 1.7e-09 37.2 0.0 11.8 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 ETS61608.1 - 8.6e-32 109.7 0.1 1.5e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 ETS61608.1 - 3.4e-05 22.1 11.5 0.35 8.9 0.3 6.5 6 2 0 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETS61608.1 - 0.00041 19.2 5.1 5.9 5.5 0.0 6.5 2 2 4 7 7 7 2 Nup133 N terminal like SLX9 PF15341.1 ETS61608.1 - 2.6 8.4 8.2 0.1 13.0 0.7 2.4 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 tRNA-synt_1b PF00579.20 ETS61609.1 - 2.7e-68 230.2 0.0 3.7e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 ETS61609.1 - 0.00086 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain HTH_IclR PF09339.5 ETS61609.1 - 1.1 8.9 5.9 0.18 11.4 0.2 2.8 3 0 0 3 3 3 0 IclR helix-turn-helix domain ABC_membrane PF00664.18 ETS61610.1 - 4.5e-79 265.7 24.7 5.1e-42 144.1 5.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS61610.1 - 8.3e-62 207.5 0.0 9.7e-32 110.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS61610.1 - 2.7e-13 49.6 0.3 0.00015 21.0 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS61610.1 - 1.5e-09 38.2 0.0 0.11 12.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 ETS61610.1 - 7.5e-08 31.9 0.3 0.18 11.1 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 ETS61610.1 - 3.3e-07 31.1 0.0 0.005 17.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_ATPase PF09818.4 ETS61610.1 - 1e-06 27.6 0.7 0.00054 18.6 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 ETS61610.1 - 3.3e-06 27.2 2.0 1.5 8.9 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 ETS61610.1 - 1.3e-05 24.5 0.5 0.052 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 ETS61610.1 - 0.00013 21.1 0.0 0.39 9.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 ETS61610.1 - 0.00016 21.5 0.2 0.24 11.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 ETS61610.1 - 0.00025 20.8 7.9 0.15 11.9 0.3 4.7 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 ETS61610.1 - 0.0018 17.4 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETS61610.1 - 0.0023 18.2 0.0 0.48 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS61610.1 - 0.0032 16.9 0.6 2 7.7 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain APS_kinase PF01583.15 ETS61610.1 - 0.0034 17.0 0.1 0.094 12.3 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase SRP54 PF00448.17 ETS61610.1 - 0.0038 16.6 0.0 0.55 9.6 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 ETS61610.1 - 0.0045 16.7 0.0 4.4 7.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 ETS61610.1 - 0.012 14.7 0.1 0.052 12.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Semialdhyde_dhC PF02774.13 ETS61610.1 - 0.04 13.7 0.1 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DUF87 PF01935.12 ETS61610.1 - 0.07 12.9 3.2 1.5 8.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_5 PF07728.9 ETS61610.1 - 0.079 12.6 0.3 1.7 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 ETS61610.1 - 0.084 11.5 2.6 5.8 5.4 0.0 3.1 3 0 0 3 3 2 0 G-protein alpha subunit PRK PF00485.13 ETS61610.1 - 0.15 11.6 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family LRR_8 PF13855.1 ETS61611.1 - 8.4e-13 47.8 14.3 3.4e-10 39.5 5.2 3.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 ETS61611.1 - 3.2e-10 39.3 17.4 7.1e-06 25.5 2.8 5.0 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS61611.1 - 4e-05 23.0 16.6 0.08 13.0 0.3 5.7 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 ETS61611.1 - 0.00093 19.0 7.7 4.4 7.6 0.1 5.1 5 0 0 5 5 5 3 Leucine Rich repeat EF_TS PF00889.14 ETS61612.1 - 9.8e-16 57.7 0.0 1.1e-13 50.9 0.0 3.1 3 0 0 3 3 3 2 Elongation factor TS POT1 PF02765.12 ETS61613.1 - 2.9e-18 66.1 0.0 5e-17 62.1 0.0 2.3 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 zf-ribbon_3 PF13248.1 ETS61613.1 - 0.0065 15.6 0.3 0.015 14.4 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 ETS61613.1 - 0.011 15.5 1.1 0.023 14.5 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 ETS61613.1 - 0.012 15.0 1.1 0.022 14.2 0.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 ETS61613.1 - 0.064 13.0 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like UPF0547 PF10571.4 ETS61613.1 - 1.3 8.7 4.5 0.6 9.8 1.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Hamartin PF04388.7 ETS61614.1 - 5.2e-38 131.1 10.0 5.2e-38 131.1 6.9 3.1 2 1 0 2 2 2 1 Hamartin protein Prominin PF05478.6 ETS61614.1 - 2.2 5.7 5.5 0.54 7.7 1.3 1.7 1 1 1 2 2 2 0 Prominin BRE1 PF08647.6 ETS61614.1 - 5.5 7.0 24.1 0.037 14.0 4.8 3.1 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.7 ETS61614.1 - 6.4 7.1 6.8 18 5.6 0.1 3.6 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sugar_tr PF00083.19 ETS61615.1 - 1.9e-35 122.3 23.4 4.2e-34 117.8 16.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS61615.1 - 2.3e-30 105.5 31.2 2.3e-30 105.5 21.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 ETS61615.1 - 0.00052 18.5 15.5 0.00083 17.8 0.5 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein tRNA-synt_2 PF00152.15 ETS61617.1 - 4e-86 288.8 0.0 5.2e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS61617.1 - 1.6e-11 43.9 0.0 3.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 ETS61617.1 - 2e-08 33.7 0.0 6.4e-05 22.2 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 ETS61617.1 - 0.012 15.2 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Aldo_ket_red PF00248.16 ETS61618.1 - 2.7e-38 131.4 0.0 1.9e-37 128.6 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family WAK PF08488.6 ETS61618.1 - 0.01 16.1 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 Wall-associated kinase X PF00739.14 ETS61618.1 - 0.046 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Trans-activation protein X Pyridoxal_deC PF00282.14 ETS61619.1 - 2.2e-21 75.7 0.0 4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 ETS61619.1 - 4.9e-07 28.8 0.0 1.1e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 ETS61619.1 - 0.0071 15.4 0.1 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 ETS61619.1 - 0.14 11.1 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II tRNA-synt_1c PF00749.16 ETS61621.1 - 2.4e-103 345.1 0.0 3.2e-103 344.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 ETS61621.1 - 8e-40 136.0 0.0 1.3e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 ETS61621.1 - 1.2e-33 116.2 0.0 4.2e-33 114.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 ETS61621.1 - 2.6e-16 60.0 2.7 2.6e-16 60.0 1.9 3.0 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CDC73 PF05179.9 ETS61622.1 - 1e-47 162.8 3.2 2e-47 161.8 2.2 1.4 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family UPF0197 PF05251.7 ETS61623.1 - 0.00061 20.0 3.4 0.00093 19.4 2.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) InaF-motif PF15018.1 ETS61623.1 - 1.6 8.2 5.3 2.7 7.5 3.7 1.3 1 0 0 1 1 1 0 TRP-interacting helix PEPCK_ATP PF01293.15 ETS61624.1 - 5.7e-221 733.9 0.0 7e-221 733.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 ETS61624.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS61624.1 - 0.24 11.3 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AMP-binding PF00501.23 ETS61625.1 - 2.2e-49 167.9 0.0 3.2e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS61625.1 - 0.00036 21.4 0.2 0.00087 20.1 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Na_Ca_ex PF01699.19 ETS61626.1 - 5e-37 126.6 43.1 1.4e-20 73.3 11.9 3.1 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Glyco_transf_22 PF03901.12 ETS61626.1 - 0.025 13.6 0.4 0.025 13.6 0.3 3.6 2 2 1 3 3 3 0 Alg9-like mannosyltransferase family SH PF01445.12 ETS61626.1 - 0.074 12.7 3.2 0.11 12.1 0.0 2.8 2 0 0 2 2 2 0 Viral small hydrophobic protein DUF4611 PF15387.1 ETS61626.1 - 1.3 9.1 4.8 0.81 9.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3684 PF12449.3 ETS61627.1 - 0 1285.9 0.0 0 1285.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 ETS61627.1 - 0.07 12.7 0.0 0.42 10.2 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MPC PF03650.8 ETS61628.1 - 4.8e-39 133.0 0.2 5.6e-39 132.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Zn_clus PF00172.13 ETS61629.1 - 2.9e-08 33.4 11.1 5.6e-08 32.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS61629.1 - 0.00027 19.9 0.0 0.0023 16.8 0.0 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Menin PF05053.8 ETS61629.1 - 2.4 6.2 7.3 4.3 5.3 5.1 1.4 1 0 0 1 1 1 0 Menin Ribosomal_S2 PF00318.15 ETS61630.1 - 1e-43 149.0 0.0 7.3e-21 74.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 MUG113 PF13455.1 ETS61631.1 - 1.9e-18 66.6 0.1 3.9e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 ETS61631.1 - 2.8e-11 43.6 0.0 7.6e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain Ribosomal_S5 PF00333.15 ETS61632.1 - 7.1e-27 92.9 3.6 7.9e-27 92.8 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 ETS61632.1 - 1.5e-21 75.4 0.0 2.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain F1F0-ATPsyn_F PF10791.4 ETS61633.1 - 4.9e-33 113.2 0.0 5.8e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi IMS PF00817.15 ETS61634.1 - 2.4e-45 153.9 0.1 4.5e-45 153.1 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETS61634.1 - 4.3e-14 52.5 1.7 1.3e-13 51.0 1.2 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 ETS61634.1 - 3.8e-06 26.6 0.0 8.8e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Peptidase_C54 PF03416.14 ETS61635.1 - 2.7e-85 285.8 0.0 1.4e-84 283.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase family C54 NAP PF00956.13 ETS61636.1 - 1.1e-86 289.9 4.7 1.1e-86 289.9 3.3 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Acetyltransf_1 PF00583.19 ETS61638.1 - 1.7e-05 24.7 0.3 0.011 15.7 0.1 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS61638.1 - 0.00011 22.3 0.0 0.00077 19.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS61638.1 - 0.016 15.0 0.2 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS61638.1 - 0.026 14.2 0.1 4.3 7.1 0.0 3.0 3 0 0 3 3 3 0 FR47-like protein Acetyltransf_10 PF13673.1 ETS61638.1 - 0.049 13.7 0.1 1.9 8.6 0.0 2.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_L39 PF00832.15 ETS61639.1 - 8.3e-10 37.9 11.1 9.7e-08 31.3 0.9 2.4 2 0 0 2 2 2 2 Ribosomal L39 protein adh_short_C2 PF13561.1 ETS61640.1 - 1.6e-30 106.6 0.1 2e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS61640.1 - 1.2e-19 70.8 0.0 1.6e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS61640.1 - 6.5e-08 32.4 0.0 9.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS61640.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein His_biosynth PF00977.16 ETS61640.1 - 0.016 14.4 0.0 0.041 13.1 0.0 1.7 2 1 0 2 2 2 0 Histidine biosynthesis protein Cbl_N3 PF02762.9 ETS61640.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Ku PF02735.11 ETS61641.1 - 2.5e-30 105.3 0.0 6.9e-30 103.9 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 ETS61641.1 - 7.5e-20 71.3 0.0 3.8e-19 69.0 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 ETS61641.1 - 4.9e-08 32.2 0.0 1.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 ETS61641.1 - 6.8e-08 32.9 0.1 2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VHS PF00790.14 ETS61641.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 VHS domain Abhydrolase_3 PF07859.8 ETS61642.1 - 7.2e-31 107.4 0.2 9.8e-31 106.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS61642.1 - 1.8e-08 34.5 1.1 2.6e-08 34.0 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS61642.1 - 8.2e-07 28.8 0.1 1.3e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS61642.1 - 0.00035 19.9 0.1 0.031 13.5 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 ETS61642.1 - 0.00092 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 ETS61642.1 - 0.0015 17.8 0.1 0.017 14.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 ETS61642.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain DUF2305 PF10230.4 ETS61642.1 - 0.032 13.6 0.0 0.07 12.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 ETS61642.1 - 0.087 12.5 0.0 0.57 9.8 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 ETS61642.1 - 0.11 12.0 0.1 1.7 8.1 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Glyco_transf_90 PF05686.7 ETS61643.1 - 9.1e-18 64.1 0.0 1.5e-16 60.1 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 90 RabGAP-TBC PF00566.13 ETS61644.1 - 1e-49 168.9 0.0 1.3e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 ETS61644.1 - 0.0066 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS61644.1 - 0.14 11.7 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain DUF4096 PF13340.1 ETS61645.1 - 0.15 11.9 1.9 0.38 10.6 1.3 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Mannosyl_trans3 PF11051.3 ETS61646.1 - 6.6e-53 179.8 0.0 9.1e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.3 ETS61647.1 - 2.7e-53 181.0 0.0 3.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative EB PF01683.13 ETS61648.1 - 0.00051 20.0 78.2 0.13 12.3 10.4 6.7 1 1 5 6 6 6 5 EB module Dickkopf_N PF04706.7 ETS61648.1 - 0.021 14.9 13.8 0.021 14.9 9.6 5.2 4 1 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region Rep_fac-A_C PF08646.5 ETS61649.1 - 2.5e-57 192.6 3.6 3.2e-55 185.8 0.2 2.2 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 ETS61649.1 - 3.7e-26 90.8 0.3 8.7e-26 89.6 0.2 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 ETS61649.1 - 5.3e-13 48.6 0.1 4.5e-11 42.4 0.0 3.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 ETS61649.1 - 0.0099 15.9 0.2 0.027 14.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF223 DZR PF12773.2 ETS61650.1 - 7.4e-06 25.6 17.5 3.5e-05 23.5 6.3 2.4 1 1 1 2 2 2 2 Double zinc ribbon RecR PF02132.10 ETS61650.1 - 1.9 7.9 13.2 0.34 10.3 2.0 2.8 2 2 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.1 ETS61650.1 - 2.8 7.2 14.3 0.22 10.7 0.4 3.6 2 1 0 2 2 2 0 zinc-ribbon domain DUF4206 PF13901.1 ETS61650.1 - 6.1 6.3 10.7 9.4 5.7 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-C3HC4_3 PF13920.1 ETS61650.1 - 9.1 6.0 16.4 4.8 6.9 2.7 3.2 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.3 ETS61651.1 - 1.3e-05 25.1 0.1 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS61651.1 - 0.00019 21.5 0.2 0.00031 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 ETS61651.1 - 0.00036 20.3 8.0 0.00036 20.3 5.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DUF2413 PF10310.4 ETS61651.1 - 0.0042 15.9 1.1 0.0064 15.3 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF3340 PF11818.3 ETS61651.1 - 0.64 9.9 7.2 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) tRNA-synt_1 PF00133.17 ETS61652.1 - 5.8e-223 741.2 0.0 7.6e-223 740.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETS61652.1 - 5e-23 81.5 0.0 9.9e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETS61652.1 - 1.2e-16 60.4 1.7 4.4e-06 25.6 0.3 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 ETS61652.1 - 0.001 18.2 0.0 0.0054 15.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Phosducin PF02114.11 ETS61653.1 - 2.5e-20 72.2 0.0 2.8e-19 68.8 0.0 2.2 1 1 0 1 1 1 1 Phosducin GATase_5 PF13507.1 ETS61654.1 - 4.3e-90 301.1 0.0 6.3e-90 300.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 ETS61654.1 - 8.6e-43 145.9 2.9 6.7e-21 74.8 0.0 2.8 2 1 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 ETS61654.1 - 8.8e-21 73.9 2.4 2.9e-20 72.3 0.0 3.1 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain zf-CCCH PF00642.19 ETS61655.1 - 4.3e-09 35.8 2.5 9.7e-09 34.7 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 ETS61655.1 - 2.7e-08 33.7 8.7 4.8e-08 32.8 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS61655.1 - 4.3e-07 29.4 5.9 7.9e-07 28.6 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS61655.1 - 2.4e-06 27.1 8.8 4.2e-06 26.3 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETS61655.1 - 2.8e-05 23.8 7.5 4.8e-05 23.0 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS61655.1 - 0.00012 21.6 8.5 0.00023 20.7 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS61655.1 - 0.00017 21.3 6.2 0.00037 20.3 4.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS61655.1 - 0.00075 19.1 4.8 0.0017 18.0 3.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 ETS61655.1 - 0.042 13.3 2.6 0.078 12.5 1.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit K_oxygenase PF13434.1 ETS61656.1 - 1.6e-85 287.0 0.0 1.7e-84 283.7 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 ETS61656.1 - 1.4e-09 38.2 0.2 1.7e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS61656.1 - 5.3e-08 32.7 2.8 5.4e-06 26.2 0.0 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding AMP-binding PF00501.23 ETS61657.1 - 8.6e-242 801.8 0.0 5.7e-85 285.2 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 ETS61657.1 - 1.5e-109 365.4 0.0 1.8e-28 99.3 0.0 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 ETS61657.1 - 1.2e-39 134.4 1.7 4.3e-09 36.5 0.0 5.5 5 0 0 5 5 5 4 Phosphopantetheine attachment site Transferase PF02458.10 ETS61657.1 - 0.021 13.3 0.0 0.63 8.4 0.0 2.8 3 0 0 3 3 3 0 Transferase family Bromodomain PF00439.20 ETS61658.1 - 2e-25 88.5 0.0 4.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 ETS61658.1 - 1.1e-09 38.3 0.2 1.9e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS61658.1 - 1.9e-08 34.2 0.1 4.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1777 PF08648.7 ETS61658.1 - 2.4 7.8 14.4 6.3 6.4 10.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) BC10 PF06726.7 ETS61659.1 - 3.1e-18 65.5 8.1 6.1e-18 64.6 5.6 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 SNF2_N PF00176.18 ETS61660.1 - 1.3e-58 198.2 0.0 1.7e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS61660.1 - 6.4e-14 51.5 0.1 1e-12 47.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS61660.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_8 PF02954.14 ETS61660.1 - 0.035 13.6 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HHH_3 PF12836.2 ETS61660.1 - 0.11 12.4 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif 2-Hacid_dh_C PF02826.14 ETS61661.1 - 6.6e-47 158.9 0.0 9.6e-47 158.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS61661.1 - 7.7e-21 73.9 0.0 1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Thioredoxin_6 PF13848.1 ETS61661.1 - 0.11 12.3 0.0 1.2 8.9 0.0 2.3 2 1 1 3 3 3 0 Thioredoxin-like domain PIN_4 PF13638.1 ETS61663.1 - 7.8e-18 64.8 0.1 7.8e-18 64.8 0.1 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 ETS61663.1 - 4.2e-17 62.2 0.0 9.3e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain DUF3610 PF12272.3 ETS61663.1 - 0.32 10.6 0.0 1.9 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3610) TPR_11 PF13414.1 ETS61664.1 - 4.3e-24 83.9 13.1 1.4e-13 50.2 0.5 4.8 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 ETS61664.1 - 1.9e-21 74.6 2.5 0.00013 21.3 0.0 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.26 ETS61664.1 - 3.7e-20 71.4 0.3 3.6e-19 68.2 0.0 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 ETS61664.1 - 4.5e-18 63.6 9.3 0.0026 17.5 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETS61664.1 - 1.8e-16 60.3 27.9 9.8e-09 35.6 1.6 5.4 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS61664.1 - 5.2e-14 52.3 21.2 5.5e-07 29.8 2.3 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETS61664.1 - 8.4e-14 51.1 16.2 8.3e-08 31.9 0.7 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS61664.1 - 9.1e-13 46.9 3.3 0.023 14.4 0.1 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS61664.1 - 2.3e-12 46.3 20.4 0.0078 16.7 0.0 7.2 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETS61664.1 - 3.3e-10 39.3 8.9 0.032 14.4 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 ETS61664.1 - 2.3e-08 34.0 13.6 0.00015 21.8 0.4 3.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETS61664.1 - 4e-06 26.2 8.2 0.59 10.0 0.0 6.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS61664.1 - 4.3e-06 26.8 21.3 0.026 14.9 0.3 7.2 8 1 0 8 8 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS61664.1 - 0.00015 21.5 2.3 13 5.8 0.0 5.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 ETS61664.1 - 0.00021 21.1 23.4 0.0018 18.2 1.2 4.8 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 ETS61664.1 - 0.0028 17.7 17.5 0.0089 16.1 1.2 4.4 2 1 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 ETS61664.1 - 0.0036 16.1 8.6 0.0066 15.2 1.5 2.7 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.4 ETS61664.1 - 0.012 14.8 0.3 0.012 14.8 0.2 2.4 3 0 0 3 3 3 0 SHNi-TPR DUF3856 PF12968.2 ETS61664.1 - 0.013 15.2 5.3 2.5 7.9 0.0 3.8 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 ETS61664.1 - 0.024 15.0 8.7 2 9.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 ETS61664.1 - 0.028 14.7 0.3 0.028 14.7 0.2 3.5 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Spectrin PF00435.16 ETS61664.1 - 0.32 11.2 10.2 1 9.6 1.2 4.1 3 2 0 3 3 3 0 Spectrin repeat SgrR_N PF12793.2 ETS61664.1 - 1.4 8.9 5.5 3.3 7.7 0.1 3.7 4 1 1 5 5 4 0 Sugar transport-related sRNA regulator N-term YfdX PF10938.3 ETS61664.1 - 2.4 7.8 22.7 3.5 7.2 3.3 4.7 3 2 1 4 4 4 0 YfdX protein ARA70 PF12489.3 ETS61665.1 - 0.088 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Nuclear coactivator DUF2431 PF10354.4 ETS61666.1 - 1.2e-27 96.8 0.0 7.2e-25 87.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) EMP70 PF02990.11 ETS61667.1 - 5.2e-181 602.6 0.3 9.8e-181 601.7 0.2 1.5 1 0 0 1 1 1 1 Endomembrane protein 70 Serinc PF03348.10 ETS61667.1 - 2.5e-147 491.0 3.3 2.5e-147 491.0 2.3 2.1 2 0 0 2 2 2 1 Serine incorporator (Serinc) Sybindin PF04099.7 ETS61668.1 - 0.0013 18.4 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family GHMP_kinases_N PF00288.21 ETS61669.1 - 3.5e-09 36.5 1.8 9.4e-09 35.2 1.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS61669.1 - 0.092 12.9 0.0 1.1 9.5 0.0 2.7 3 1 0 3 3 3 0 GHMP kinases C terminal Brix PF04427.13 ETS61670.1 - 1.8e-43 148.4 0.1 2.4e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain HSF_DNA-bind PF00447.12 ETS61672.1 - 5.3e-39 132.5 1.1 4.7e-26 90.9 0.1 2.3 1 1 1 2 2 2 2 HSF-type DNA-binding TFIIA PF03153.8 ETS61673.1 - 2.9e-51 175.5 20.8 1.3e-31 110.8 12.2 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF1958 PF09211.5 ETS61673.1 - 0.08 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) PWWP PF00855.12 ETS61674.1 - 2.1e-15 56.7 0.0 2.1e-15 56.7 0.0 3.0 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 ETS61674.1 - 2.4e-05 23.7 0.0 5.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain BUD22 PF09073.5 ETS61674.1 - 0.31 10.0 30.6 0.067 12.2 17.0 2.1 2 0 0 2 2 2 0 BUD22 Daxx PF03344.10 ETS61674.1 - 0.81 8.0 19.8 0.97 7.8 13.7 1.1 1 0 0 1 1 1 0 Daxx Family Herpes_DNAp_acc PF04929.7 ETS61674.1 - 0.9 8.4 4.8 1.8 7.4 3.3 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PI3K_1B_p101 PF10486.4 ETS61674.1 - 1.4 6.4 4.6 1.7 6.1 3.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hid1 PF12722.2 ETS61674.1 - 1.8 6.1 8.8 2.2 5.8 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.1 ETS61674.1 - 4.9 5.3 5.8 6.5 4.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pam17 PF08566.5 ETS61675.1 - 0.0026 17.4 0.2 0.0061 16.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BRE1 PF08647.6 ETS61676.1 - 2.2e-24 85.2 7.0 2.2e-24 85.2 4.8 7.9 5 1 2 7 7 7 2 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.20 ETS61676.1 - 7e-06 25.5 13.3 1.2e-05 24.8 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS61676.1 - 1.1e-05 25.3 12.9 1.7e-05 24.7 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS61676.1 - 1.5e-05 24.6 13.0 2.7e-05 23.8 9.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS61676.1 - 0.00014 21.4 9.7 0.00025 20.6 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 ETS61676.1 - 0.00016 21.3 2.7 0.00032 20.4 1.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Tropomyosin PF00261.15 ETS61676.1 - 0.00026 20.1 15.6 0.00026 20.1 10.8 5.8 4 2 1 5 5 4 2 Tropomyosin Lebercilin PF15619.1 ETS61676.1 - 0.0011 18.4 16.5 0.0011 18.4 11.4 6.8 2 2 5 7 7 5 1 Ciliary protein causing Leber congenital amaurosis disease zf-RING_2 PF13639.1 ETS61676.1 - 0.0017 18.1 11.3 0.0029 17.3 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain Filament PF00038.16 ETS61676.1 - 0.069 12.6 85.3 0.17 11.2 8.1 6.2 2 1 4 6 6 6 0 Intermediate filament protein UPF0547 PF10571.4 ETS61676.1 - 0.087 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-rbx1 PF12678.2 ETS61676.1 - 0.24 11.5 6.0 0.46 10.6 4.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 ETS61676.1 - 2.1 8.2 8.7 3.8 7.4 6.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myosin_tail_1 PF01576.14 ETS61676.1 - 4.8 4.7 103.5 1.3 6.6 59.2 4.2 2 2 0 2 2 2 0 Myosin tail DZR PF12773.2 ETS61676.1 - 8 6.3 7.7 18 5.2 5.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon RNA_pol_N PF01194.12 ETS61677.1 - 1.4e-28 98.6 0.4 1.8e-28 98.3 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit SecY PF00344.15 ETS61678.1 - 2.7e-97 325.7 7.1 3.5e-97 325.4 4.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 ETS61678.1 - 3.9e-18 64.6 0.2 1.3e-17 63.0 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.6 ETS61678.1 - 0.084 12.5 2.8 1.3 8.7 0.0 3.4 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Ribosom_S12_S23 PF00164.20 ETS61679.1 - 1.4e-37 127.7 0.6 2.2e-37 127.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Metallophos PF00149.23 ETS61682.1 - 2.7e-38 131.4 1.0 4.2e-38 130.7 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_carr PF00153.22 ETS61682.1 - 1.4e-08 34.2 0.2 0.00051 19.6 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein Rax2 PF12768.2 ETS61683.1 - 1e-77 261.1 7.7 2.7e-63 213.8 0.0 4.5 5 1 0 5 5 5 3 Cortical protein marker for cell polarity SH3_1 PF00018.23 ETS61683.1 - 5.2e-14 51.3 0.0 1.2e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS61683.1 - 7.2e-12 44.6 0.1 2.5e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 ETS61683.1 - 4.4e-07 29.2 0.0 1.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1918 PF08940.6 ETS61683.1 - 0.0092 15.2 0.2 0.078 12.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1918) Kelch_6 PF13964.1 ETS61683.1 - 0.015 15.4 6.5 0.77 10.0 0.0 5.5 4 1 1 5 5 5 0 Kelch motif CcoS PF03597.10 ETS61683.1 - 7.9 6.0 7.7 27 4.3 5.4 1.9 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type HIT PF01230.18 ETS61685.1 - 2.5e-19 69.6 1.0 4.1e-19 68.9 0.3 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 ETS61685.1 - 3.8e-14 52.8 0.2 7.8e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 ETS61685.1 - 5.2e-06 26.1 0.0 7.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Peptidase_C80 PF11713.3 ETS61685.1 - 0.086 12.6 0.1 5.2 6.8 0.0 2.1 1 1 1 2 2 2 0 Peptidase C80 family PIG-P PF08510.7 ETS61686.1 - 7.9e-31 106.3 0.9 1.1e-30 105.8 0.6 1.2 1 0 0 1 1 1 1 PIG-P CIA30 PF08547.7 ETS61686.1 - 1.6e-14 54.0 0.0 1.9e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) DUF4131 PF13567.1 ETS61686.1 - 0.047 13.1 3.3 0.076 12.4 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DPM2 PF07297.7 ETS61686.1 - 0.58 10.4 4.2 1 9.7 2.9 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Reo_sigmaC PF04582.7 ETS61687.1 - 0.38 9.8 35.0 0.048 12.8 1.1 4.5 1 1 1 4 4 4 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 ETS61687.1 - 0.83 9.4 31.8 0.1 12.4 1.7 4.9 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 ETS61687.1 - 3 7.6 93.0 0.12 12.1 12.2 6.2 2 2 2 5 5 5 0 Autophagy protein 16 (ATG16) Vps53_N PF04100.7 ETS61688.1 - 3.4e-91 305.8 0.1 6e-91 305.0 0.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 ETS61688.1 - 0.0021 16.9 6.4 0.0039 16.1 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 ETS61688.1 - 0.0071 14.5 3.3 0.0077 14.4 1.2 1.8 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.7 ETS61688.1 - 5 6.9 8.7 6.9 6.4 4.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DEAD PF00270.24 ETS61689.1 - 7.6e-39 132.9 0.0 1.5e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 ETS61689.1 - 2.2e-21 75.4 1.0 2.2e-21 75.4 0.7 3.1 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 ETS61689.1 - 1.8e-20 72.5 0.0 5.6e-20 70.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS61689.1 - 0.0014 18.5 0.0 0.0063 16.3 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC4 PF02732.10 ETS61690.1 - 9.3e-15 54.6 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Phage_holin_1 PF04531.8 ETS61691.1 - 1.8 8.6 5.4 4.7 7.3 0.1 3.1 3 0 0 3 3 3 0 Bacteriophage holin DUF2109 PF09882.4 ETS61691.1 - 1.8 8.5 7.5 1.3 9.0 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) Ribonuclease PF00545.15 ETS61692.1 - 1.3e-07 31.6 0.0 2.4e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 ribonuclease Oxysterol_BP PF01237.13 ETS61693.1 - 8.1e-80 267.9 0.0 1.7e-79 266.9 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Put_Phosphatase PF06888.7 ETS61693.1 - 6.1e-52 176.1 0.0 1.1e-51 175.2 0.0 1.4 1 0 0 1 1 1 1 Putative Phosphatase Ank PF00023.25 ETS61693.1 - 4.3e-19 67.2 0.4 5e-06 26.0 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 ETS61693.1 - 6e-18 64.9 3.8 4.2e-13 49.4 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS61693.1 - 3.3e-17 62.0 2.7 3.4e-07 30.2 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS61693.1 - 1.6e-15 55.6 0.3 0.00011 22.1 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 ETS61693.1 - 4.6e-10 39.7 2.9 4.3e-05 23.9 0.2 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.24 ETS61693.1 - 3.1e-09 36.9 0.0 6.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETS61693.1 - 2.7e-08 34.0 0.2 8.2e-08 32.4 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain HAD_2 PF13419.1 ETS61693.1 - 1.5e-07 31.7 2.2 8e-07 29.4 0.0 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase PH_8 PF15409.1 ETS61693.1 - 2e-06 27.7 0.1 6.3e-06 26.1 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Shigella_OspC PF06128.6 ETS61693.1 - 0.096 12.1 0.4 0.31 10.5 0.3 1.8 1 1 0 1 1 1 0 Shigella flexneri OspC protein Asp PF00026.18 ETS61694.1 - 3.3e-36 125.1 0.0 4.5e-35 121.4 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS61694.1 - 0.00019 21.4 0.1 0.00042 20.2 0.1 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal RhoGEF PF00621.15 ETS61696.1 - 3.4e-16 59.6 0.0 5.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain CBFD_NFYB_HMF PF00808.18 ETS61697.1 - 5.3e-14 52.0 0.2 8.2e-14 51.4 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS61697.1 - 5.2e-06 26.4 0.3 8.1e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Cwf_Cwc_15 PF04889.7 ETS61697.1 - 0.31 10.7 14.4 0.38 10.4 10.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.6 ETS61697.1 - 0.85 9.4 10.0 1.3 8.8 7.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Astro_capsid PF03115.9 ETS61697.1 - 1.5 6.9 6.1 1.5 7.0 4.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pox_Ag35 PF03286.9 ETS61697.1 - 3.3 7.1 10.7 4.2 6.8 7.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_mis_repair PF01119.14 ETS61698.1 - 2.8e-31 107.4 0.0 4.7e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 ETS61698.1 - 1.1e-11 44.5 0.0 2.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETS61698.1 - 3.2e-10 39.6 0.0 2.6e-09 36.7 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EBP PF05241.7 ETS61699.1 - 2.9e-56 189.5 11.8 5.2e-56 188.7 8.1 1.4 1 0 0 1 1 1 1 Emopamil binding protein Glycos_transf_1 PF00534.15 ETS61699.1 - 6.4e-15 54.9 0.0 1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETS61699.1 - 6.7e-06 26.2 0.1 4.2e-05 23.7 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 ETS61699.1 - 3.9e-05 23.4 0.3 0.00025 20.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 7tm_1 PF00001.16 ETS61699.1 - 0.0045 16.1 0.0 0.073 12.2 0.0 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_trans_4_4 PF13579.1 ETS61699.1 - 0.16 12.0 13.8 0.022 14.9 4.3 3.3 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain B12D PF06522.6 ETS61701.1 - 1.3e-05 24.7 0.0 3.6e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ras PF00071.17 ETS61702.1 - 3.4e-53 179.3 0.0 5.1e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS61702.1 - 8.6e-16 58.5 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61702.1 - 3.2e-10 39.5 0.0 6.5e-10 38.5 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS61702.1 - 6.4e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS61702.1 - 0.0028 17.0 0.0 0.06 12.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETS61702.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 ETS61702.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 ETS61702.1 - 0.14 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SWIRM PF04433.12 ETS61703.1 - 5.1e-16 58.5 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain DEAD PF00270.24 ETS61704.1 - 1.7e-45 154.5 0.0 2.9e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS61704.1 - 3.3e-27 94.1 0.0 8.3e-27 92.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BSP_II PF05432.6 ETS61704.1 - 0.00074 18.8 9.5 0.0012 18.2 6.6 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) ResIII PF04851.10 ETS61704.1 - 0.0035 17.1 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Daxx PF03344.10 ETS61704.1 - 0.099 11.1 13.9 0.14 10.5 9.6 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETS61704.1 - 0.26 9.1 11.7 0.43 8.4 8.1 1.3 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.8 ETS61704.1 - 2.1 7.3 8.9 3.3 6.7 6.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SAPS PF04499.10 ETS61704.1 - 4.1 5.9 5.0 6.1 5.3 3.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.9 ETS61704.1 - 5.2 6.5 11.0 11 5.4 7.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-HIT PF04438.11 ETS61705.1 - 1.9e-08 33.7 9.5 2.9e-08 33.2 6.6 1.3 1 0 0 1 1 1 1 HIT zinc finger Pkinase PF00069.20 ETS61706.1 - 6.2e-40 136.9 0.0 3.2e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61706.1 - 3.5e-24 85.2 0.0 5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS61706.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3844 PF12955.2 ETS61707.1 - 4.5e-30 103.7 1.4 7.1e-30 103.1 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) DUF521 PF04412.8 ETS61707.1 - 0.054 12.0 0.1 0.087 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) ERO1 PF04137.10 ETS61708.1 - 4.1e-127 424.1 0.0 5.1e-127 423.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CDP-OH_P_transf PF01066.16 ETS61709.1 - 1e-16 61.0 4.8 1e-16 61.0 3.3 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PPTA PF01239.17 ETS61710.1 - 3e-39 130.7 18.7 7.4e-09 34.5 1.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat YfaZ PF07437.6 ETS61711.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 YfaZ precursor Glyco_hydro_30 PF02055.11 ETS61712.1 - 6.3e-09 34.5 2.8 1.2e-07 30.2 0.5 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.10 ETS61712.1 - 0.0058 14.7 0.4 0.011 13.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 DEC-1_N PF04625.8 ETS61712.1 - 0.013 14.1 0.7 0.027 13.1 0.5 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Muskelin_N PF06588.6 ETS61714.1 - 8.1e-52 175.8 0.3 1.2e-19 70.8 0.0 3.5 3 1 0 3 3 3 3 Muskelin N-terminus Kelch_3 PF13415.1 ETS61714.1 - 7.1e-20 70.6 13.1 1.7e-07 31.2 0.1 7.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS61714.1 - 2e-17 62.6 7.8 1.8e-06 27.5 0.2 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS61714.1 - 2.2e-14 53.0 3.7 0.0043 16.9 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 ETS61714.1 - 8.5e-14 51.0 2.0 0.01 16.0 0.0 7.1 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.20 ETS61714.1 - 2.7e-09 36.3 1.1 0.0045 16.5 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 ETS61714.1 - 0.011 15.4 11.4 0.039 13.7 0.2 5.2 6 0 0 6 6 6 0 Kelch motif SAP PF02037.22 ETS61715.1 - 4.5e-12 45.1 0.3 1.2e-11 43.8 0.2 1.8 1 0 0 1 1 1 1 SAP domain CCT_2 PF09425.5 ETS61715.1 - 0.019 14.4 0.1 0.069 12.7 0.1 2.1 1 0 0 1 1 1 0 Divergent CCT motif Glyco_hydro_2 PF00703.16 ETS61718.1 - 0.002 18.5 0.0 0.0045 17.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 FAD_binding_3 PF01494.14 ETS61719.1 - 3.6e-22 78.8 0.0 1.2e-21 77.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 ETS61719.1 - 4.3e-05 22.3 0.8 0.0018 16.9 0.0 2.1 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 ETS61719.1 - 0.00013 21.9 0.9 0.00034 20.5 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS61719.1 - 0.00039 20.7 0.4 0.001 19.4 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS61719.1 - 0.0014 17.6 2.8 0.017 14.0 1.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS61719.1 - 0.0022 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS61719.1 - 0.003 16.4 2.2 0.005 15.7 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 ETS61719.1 - 0.0094 15.0 0.1 0.31 10.0 0.0 2.8 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 ETS61719.1 - 0.015 15.1 0.9 0.027 14.3 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS61719.1 - 0.045 12.2 0.8 0.069 11.5 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 ETS61719.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS61719.1 - 0.097 11.4 0.0 3.2 6.5 0.0 2.3 2 1 0 2 2 2 0 Squalene epoxidase NAD_Gly3P_dh_N PF01210.18 ETS61719.1 - 0.11 12.1 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 ETS61719.1 - 0.13 11.1 0.2 6 5.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 ETS61719.1 - 0.14 10.9 1.2 0.21 10.3 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 ETS61719.1 - 0.25 10.9 0.4 0.54 9.8 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PRA1 PF03208.14 ETS61720.1 - 7.4e-39 132.5 1.1 8.6e-39 132.3 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2306 PF10067.4 ETS61720.1 - 0.058 13.5 0.4 0.1 12.7 0.2 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) Tetraspannin PF00335.15 ETS61720.1 - 3.1 7.0 7.0 4.7 6.4 4.8 1.3 1 0 0 1 1 1 0 Tetraspanin family YscJ_FliF PF01514.12 ETS61721.1 - 0.016 14.3 0.4 0.03 13.4 0.3 1.3 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family tRNA-synt_2c PF01411.14 ETS61722.1 - 5.5e-212 704.9 0.0 7.5e-212 704.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 ETS61722.1 - 2.3e-17 62.5 0.2 6.4e-17 61.1 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 ETS61722.1 - 3e-06 26.8 1.9 1.1e-05 24.9 1.3 2.1 1 0 0 1 1 1 1 DHHA1 domain IMD PF08397.6 ETS61722.1 - 0.042 13.1 5.6 0.01 15.1 1.3 1.7 2 0 0 2 2 2 0 IRSp53/MIM homology domain DUF1767 PF08585.7 ETS61723.1 - 6.2e-12 45.6 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Ribosomal_S8e PF01201.17 ETS61724.1 - 3.7e-37 127.4 7.7 5.7e-36 123.5 5.3 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 ETS61724.1 - 0.056 13.3 3.5 0.058 13.3 0.9 1.8 1 1 1 2 2 2 0 Mer2 AAA_13 PF13166.1 ETS61724.1 - 0.67 8.3 5.7 0.83 8.0 4.0 1.0 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 ETS61724.1 - 5.6 5.1 10.9 7.4 4.7 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Na_Ca_ex PF01699.19 ETS61726.1 - 1e-28 99.6 13.5 1.1e-15 57.4 0.0 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF2360 PF10152.4 ETS61726.1 - 0.028 14.6 3.3 4.2 7.6 0.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pex14_N PF04695.8 ETS61726.1 - 0.059 13.4 6.1 2.9 7.9 0.7 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 ETS61726.1 - 0.078 11.0 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4552 PF15089.1 ETS61726.1 - 5.6 5.7 5.2 7.4 5.3 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) SIR2 PF02146.12 ETS61727.1 - 1.3e-29 103.1 0.0 4e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 Sir2 family SF3b1 PF08920.5 ETS61728.1 - 2.5e-26 92.4 0.5 2.5e-26 92.4 0.3 2.8 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 ETS61728.1 - 2.7e-16 59.6 5.6 2.8e-05 24.3 0.0 7.9 6 2 4 10 10 10 6 HEAT repeats HEAT_EZ PF13513.1 ETS61728.1 - 4.2e-09 36.6 6.6 0.34 11.4 0.0 8.1 7 2 2 9 9 8 3 HEAT-like repeat HEAT PF02985.17 ETS61728.1 - 4.3e-08 32.5 7.6 0.4 10.9 0.0 8.8 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 ETS61728.1 - 2.6e-07 29.3 1.4 0.13 10.5 0.0 3.9 2 2 1 4 4 4 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 ETS61728.1 - 6.4e-06 26.4 0.4 1.6 9.1 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 ETS61728.1 - 0.00036 19.9 0.5 0.24 10.7 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal Dopey_N PF04118.9 ETS61728.1 - 0.01 14.6 0.3 0.073 11.8 0.0 2.4 3 0 0 3 3 3 0 Dopey, N-terminal TIP120 PF08623.5 ETS61728.1 - 0.021 14.4 0.7 2.5 7.6 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) MMS19_N PF14500.1 ETS61728.1 - 0.03 13.6 0.4 19 4.3 0.0 3.8 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II SPO22 PF08631.5 ETS61728.1 - 0.16 11.0 0.3 2.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF2945 PF11160.3 ETS61729.1 - 0.002 17.8 3.4 0.0031 17.2 2.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) GMC_oxred_C PF05199.8 ETS61730.1 - 1.6e-13 51.1 0.1 3.7e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS61730.1 - 2.5e-09 36.7 0.0 4.7e-08 32.5 0.0 2.3 1 1 0 1 1 1 1 GMC oxidoreductase MAPEG PF01124.13 ETS61730.1 - 1.8e-07 30.8 0.3 4.6e-07 29.5 0.2 1.6 1 0 0 1 1 1 1 MAPEG family Pyr_redox_3 PF13738.1 ETS61730.1 - 0.00051 20.1 0.1 0.22 11.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS61730.1 - 0.0039 17.1 0.1 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS61730.1 - 0.0041 17.0 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS61730.1 - 0.0049 15.8 1.8 0.021 13.7 0.0 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase FtsQ PF03799.10 ETS61730.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Cell division protein FtsQ FAD_binding_2 PF00890.19 ETS61730.1 - 0.056 12.2 1.0 0.093 11.5 0.1 1.8 3 0 0 3 3 3 0 FAD binding domain Glyco_trans_2_3 PF13632.1 ETS61731.1 - 5.7e-41 140.3 2.7 5.7e-41 140.3 1.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS61731.1 - 7.1e-08 32.5 0.0 2.5e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS61731.1 - 0.00021 20.9 0.0 0.0091 15.6 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ETS61731.1 - 0.067 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 ETS61732.1 - 1.1e-19 70.4 0.2 3.5e-19 68.7 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 ETS61733.1 - 3.5e-22 78.5 1.0 6.8e-22 77.6 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 ETS61734.1 - 2e-39 135.2 9.4 2e-39 135.2 6.5 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS61734.1 - 2.2e-07 30.9 0.1 1.1e-06 28.6 0.2 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS61734.1 - 0.0058 16.3 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cutinase PF01083.17 ETS61736.1 - 1.6e-16 60.5 0.1 4.8e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Cutinase PAP2 PF01569.16 ETS61737.1 - 3.2e-19 68.8 3.2 3.2e-19 68.8 2.2 2.3 2 0 0 2 2 2 1 PAP2 superfamily AAA PF00004.24 ETS61738.1 - 1.3e-85 284.2 0.0 2.2e-42 144.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS61738.1 - 6.8e-14 51.7 0.0 3.3e-07 30.1 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS61738.1 - 1.6e-12 47.7 1.5 9.6e-06 25.7 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain RuvB_N PF05496.7 ETS61738.1 - 3.5e-11 42.5 0.0 6.9e-05 22.0 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETS61738.1 - 7.1e-10 39.1 0.2 0.00037 20.6 0.1 4.1 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 ETS61738.1 - 3.1e-09 36.0 0.0 0.0017 17.1 0.0 2.7 3 0 0 3 3 3 2 TIP49 C-terminus AAA_17 PF13207.1 ETS61738.1 - 3.3e-09 37.5 0.0 4.6e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS61738.1 - 7.9e-08 32.2 0.0 0.0001 22.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 ETS61738.1 - 1.8e-07 31.0 0.0 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ETS61738.1 - 5.2e-07 28.9 0.0 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 ETS61738.1 - 9.4e-07 28.4 2.6 0.013 14.8 0.1 3.8 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 ETS61738.1 - 1.9e-06 27.3 0.0 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 ETS61738.1 - 3.5e-06 27.0 0.0 0.16 11.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 ETS61738.1 - 8.7e-06 25.8 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 ETS61738.1 - 1.3e-05 25.2 0.1 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS61738.1 - 1.4e-05 24.7 2.6 0.0029 17.3 0.2 3.4 3 0 0 3 3 2 1 Part of AAA domain RNA_helicase PF00910.17 ETS61738.1 - 1.8e-05 24.8 0.0 0.092 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 ETS61738.1 - 4.7e-05 22.6 0.5 0.23 10.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETS61738.1 - 0.00027 21.2 0.0 0.027 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 ETS61738.1 - 0.00048 19.7 0.9 0.017 14.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 ETS61738.1 - 0.0011 18.5 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 ETS61738.1 - 0.0014 18.3 0.1 1.4 8.5 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activat PF00158.21 ETS61738.1 - 0.0016 17.8 0.0 1.8 8.0 0.0 3.5 3 1 0 3 3 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 ETS61738.1 - 0.0027 16.6 0.0 0.24 10.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 ETS61738.1 - 0.0032 16.4 0.0 0.036 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 ETS61738.1 - 0.0034 16.1 0.0 0.18 10.4 0.0 2.6 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 ETS61738.1 - 0.0078 15.8 0.1 0.5 10.0 0.0 3.2 3 1 1 4 4 3 1 NACHT domain UPF0079 PF02367.12 ETS61738.1 - 0.0081 15.7 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DAP3 PF10236.4 ETS61738.1 - 0.015 14.2 0.0 0.036 12.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 ETS61738.1 - 0.017 15.4 0.0 0.94 9.7 0.0 2.6 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.11 ETS61738.1 - 0.017 14.3 0.3 0.72 9.0 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 ETS61738.1 - 0.021 14.4 0.0 0.34 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 ETS61738.1 - 0.026 13.6 0.0 2.9 6.9 0.0 2.6 2 0 0 2 2 2 0 KaiC SKI PF01202.17 ETS61738.1 - 0.033 14.0 0.1 5.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 ETS61738.1 - 0.041 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 ETS61738.1 - 0.052 12.7 0.2 1.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.10 ETS61738.1 - 0.12 12.0 0.8 3.5 7.3 0.0 3.0 2 2 2 4 4 3 0 NTPase GDI PF00996.13 ETS61739.1 - 2e-55 187.9 0.0 1.1e-52 178.8 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Abhydrolase_3 PF07859.8 ETS61739.1 - 0.004 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sas10_Utp3 PF04000.10 ETS61740.1 - 4.4e-09 36.4 0.7 1e-08 35.2 0.5 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Zn_clus PF00172.13 ETS61741.1 - 2.4e-05 24.1 9.2 5.5e-05 22.9 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKN1 PF03935.10 ETS61742.1 - 9.3e-202 670.6 0.0 1.1e-201 670.3 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 ETS61742.1 - 4e-06 26.2 0.2 0.00064 19.0 0.0 2.8 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 zf-C2H2 PF00096.21 ETS61743.1 - 1.5e-12 47.0 14.0 8.2e-06 25.8 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS61743.1 - 1.1e-10 41.0 14.2 0.00049 20.2 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS61743.1 - 2e-05 24.6 14.3 0.036 14.3 0.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 ETS61743.1 - 0.22 11.6 4.8 5.5 7.1 3.5 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 ETS61743.1 - 0.59 9.7 3.4 3.9 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 ETS61743.1 - 0.61 9.8 2.4 11 5.9 0.0 2.4 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_4 PF13717.1 ETS61743.1 - 0.96 9.2 4.0 4.3 7.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 ETS61743.1 - 2.2 8.4 5.2 4.2 7.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 ETS61743.1 - 5.3 6.9 9.5 9.4 6.1 0.8 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Seryl_tRNA_N PF02403.17 ETS61744.1 - 0.073 13.0 2.4 0.17 11.9 1.6 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AT_hook PF02178.14 ETS61745.1 - 4.5e-08 31.8 80.6 0.045 13.4 1.2 8.2 8 0 0 8 8 8 7 AT hook motif SlyX PF04102.7 ETS61745.1 - 0.068 13.5 1.4 0.18 12.2 1.0 1.7 1 0 0 1 1 1 0 SlyX CENP-F_N PF10481.4 ETS61745.1 - 1.3 8.3 6.8 6.2 6.1 0.1 3.2 2 1 1 3 3 3 0 Cenp-F N-terminal domain DUF1191 PF06697.7 ETS61746.1 - 0.0012 17.6 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) SKG6 PF08693.5 ETS61746.1 - 0.0033 16.7 0.3 0.0084 15.3 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 ETS61746.1 - 0.011 15.3 0.3 0.028 14.0 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 ETS61746.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.3 ETS61746.1 - 0.047 13.7 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 Herpes_gE PF02480.11 ETS61746.1 - 0.21 9.8 0.0 0.21 9.8 0.0 2.9 3 1 1 4 4 4 0 Alphaherpesvirus glycoprotein E IncA PF04156.9 ETS61746.1 - 0.65 9.5 0.0 0.65 9.5 0.0 2.4 3 0 0 3 3 3 0 IncA protein Adeno_E3_CR2 PF02439.10 ETS61747.1 - 0.073 12.6 0.5 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 ETS61747.1 - 0.16 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 ETS61747.1 - 0.24 11.0 0.5 0.46 10.1 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain FAD_binding_1 PF00667.15 ETS61748.1 - 1.1e-51 175.3 0.0 2e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 ETS61748.1 - 7.1e-08 32.9 0.3 3e-07 30.9 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS61748.1 - 0.05 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Peptidase_M16_C PF05193.16 ETS61748.1 - 0.096 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain DUF3729 PF12526.3 ETS61748.1 - 2.6 9.4 12.3 0.63 11.4 4.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) APG12 PF04110.8 ETS61749.1 - 3.4e-33 113.6 0.0 4.4e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 ETS61749.1 - 0.00068 19.5 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ribosomal_L30_N PF08079.7 ETS61750.1 - 1.1e-24 86.1 18.6 1.8e-24 85.5 12.9 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 ETS61750.1 - 9.8e-18 63.4 1.6 2.3e-17 62.2 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e NinG PF05766.7 ETS61750.1 - 0.59 9.8 6.4 1 9.0 4.4 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Alk_phosphatase PF00245.15 ETS61751.1 - 2.5e-75 253.7 0.0 5.6e-66 222.9 0.0 2.1 2 0 0 2 2 2 2 Alkaline phosphatase LRR_4 PF12799.2 ETS61752.1 - 0.0033 17.0 2.1 0.95 9.1 0.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 ETS61752.1 - 0.059 13.5 0.9 29 5.4 0.0 4.2 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 ETS61752.1 - 0.083 12.9 0.1 32 5.0 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Y_phosphatase2 PF03162.8 ETS61753.1 - 5e-49 165.8 0.0 8.9e-49 165.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Prefoldin PF02996.12 ETS61753.1 - 2e-29 101.6 0.2 3e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Y_phosphatase3 PF13350.1 ETS61753.1 - 2.5e-08 34.3 0.0 2.5e-06 27.8 0.0 2.7 1 1 1 2 2 2 1 Tyrosine phosphatase family OHCU_decarbox PF09349.5 ETS61754.1 - 5.6e-31 107.9 0.4 1.5e-30 106.5 0.0 2.0 2 0 0 2 2 2 1 OHCU decarboxylase adh_short PF00106.20 ETS61755.1 - 2.5e-34 118.6 1.5 3.3e-34 118.2 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS61755.1 - 2.2e-14 53.5 0.2 3e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS61755.1 - 2.1e-09 37.5 0.0 2.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS61755.1 - 0.00011 21.7 0.1 0.00018 21.0 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS61755.1 - 0.00011 21.8 0.1 0.00021 20.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 ETS61755.1 - 0.00025 20.7 0.6 0.00049 19.8 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS61755.1 - 0.0008 19.4 2.4 0.0034 17.4 1.7 2.1 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 ETS61755.1 - 0.00095 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 ETS61755.1 - 0.0013 17.7 0.1 0.0031 16.5 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 ETS61755.1 - 0.0088 15.0 0.2 0.012 14.6 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 ETS61755.1 - 0.033 13.6 0.7 0.057 12.8 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 ETS61755.1 - 0.06 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 ETS61755.1 - 0.073 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DASH_Dad3 PF08656.5 ETS61757.1 - 8e-21 73.5 0.7 1.2e-20 72.9 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad3 Abhydrolase_6 PF12697.2 ETS61758.1 - 2e-29 103.1 7.1 2.7e-29 102.6 4.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS61758.1 - 6.1e-16 58.6 0.4 8.8e-16 58.1 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS61758.1 - 1.1e-11 44.6 0.2 4.2e-11 42.8 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS61758.1 - 1.7e-05 24.5 0.0 0.00021 21.0 0.0 2.2 1 1 1 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 ETS61758.1 - 0.009 14.5 0.0 0.02 13.3 0.0 1.5 2 0 0 2 2 2 1 Ndr family Prok-RING_4 PF14447.1 ETS61758.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PAE PF03283.8 ETS61762.1 - 3.4e-15 55.5 0.3 5.6e-15 54.8 0.2 1.2 1 0 0 1 1 1 1 Pectinacetylesterase RNA_pol_I_A49 PF06870.7 ETS61763.1 - 5.9e-126 420.1 0.9 6.7e-126 419.9 0.0 1.5 2 0 0 2 2 2 1 A49-like RNA polymerase I associated factor DUF2201_N PF13203.1 ETS61763.1 - 8.5 5.4 9.1 54 2.8 5.1 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain PHP PF02811.14 ETS61764.1 - 1.5e-09 37.9 0.1 1.8e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 PHP domain FA_hydroxylase PF04116.8 ETS61765.1 - 4.4e-14 52.8 25.9 7.6e-14 52.0 15.3 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mtc PF03820.12 ETS61766.1 - 1.5e-93 312.8 0.1 1.8e-93 312.5 0.1 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 ETS61767.1 - 1.4e-43 145.2 13.6 5.8e-09 35.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF2415 PF10313.4 ETS61767.1 - 0.0012 18.5 0.0 0.0099 15.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) DAZAP2 PF11029.3 ETS61767.1 - 0.037 14.4 3.9 0.083 13.3 2.7 1.5 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) gag_pre-integrs PF13976.1 ETS61767.1 - 0.13 11.9 1.2 5.6 6.6 0.4 2.9 3 0 0 3 3 3 0 GAG-pre-integrase domain p450 PF00067.17 ETS61768.1 - 1.7e-26 92.7 0.1 5.1e-26 91.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ENTH PF01417.15 ETS61769.1 - 5.4e-51 171.6 0.2 1.1e-50 170.6 0.1 1.5 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 ETS61769.1 - 8.4e-05 21.8 7.4 0.012 15.1 1.9 3.2 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.11 ETS61769.1 - 0.00013 20.7 1.0 0.00025 19.8 0.7 1.5 1 0 0 1 1 1 1 ANTH domain PAT1 PF09770.4 ETS61769.1 - 0.099 10.8 49.0 0.14 10.3 33.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3235 PF11574.3 ETS61769.1 - 0.29 11.3 6.8 0.98 9.7 4.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Septin PF00735.13 ETS61770.1 - 2e-114 381.3 0.2 2.7e-114 380.9 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 ETS61770.1 - 1.5e-08 34.5 0.0 3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS61770.1 - 1.6e-07 30.9 1.9 1.1e-05 25.0 0.2 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETS61770.1 - 1.6e-07 30.6 0.1 4.3e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 ETS61770.1 - 3.6e-05 23.2 0.5 0.00013 21.4 0.3 1.9 1 1 0 1 1 1 1 Ras family AAA_24 PF13479.1 ETS61770.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ETS61770.1 - 0.00034 20.1 0.0 0.00081 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 ETS61770.1 - 0.00035 19.7 0.1 0.00075 18.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 ETS61770.1 - 0.00039 20.8 0.1 0.0014 19.1 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 ETS61770.1 - 0.00095 19.2 0.8 0.0047 16.9 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS61770.1 - 0.0011 19.1 2.2 0.0045 17.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 ETS61770.1 - 0.0013 18.2 1.5 0.057 12.9 0.3 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 ETS61770.1 - 0.0015 17.7 0.4 0.0041 16.2 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 ETS61770.1 - 0.0018 18.5 0.2 0.0051 17.1 0.0 1.8 2 0 0 2 2 1 1 ABC transporter MobB PF03205.9 ETS61770.1 - 0.0032 17.1 0.4 0.0076 15.9 0.1 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 ETS61770.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 ETS61770.1 - 0.017 14.2 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.13 ETS61770.1 - 0.025 13.8 0.1 0.073 12.3 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 ETS61770.1 - 0.025 14.1 0.2 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 ETS61770.1 - 0.035 14.0 0.5 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS61770.1 - 0.037 14.3 0.7 0.16 12.2 0.5 2.1 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETS61770.1 - 0.043 13.2 0.1 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 ETS61770.1 - 0.047 13.1 2.9 0.079 12.4 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 ETS61770.1 - 0.051 13.1 2.3 2.2 7.7 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 ETS61770.1 - 0.062 13.1 1.2 0.2 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS61770.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 ETS61770.1 - 0.068 12.6 0.4 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 ETS61770.1 - 0.074 12.8 7.6 1.2 8.9 0.2 2.8 2 1 1 3 3 3 0 Dynamin family Pox_A32 PF04665.7 ETS61770.1 - 0.096 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ArgK PF03308.11 ETS61770.1 - 0.2 10.4 2.7 0.75 8.5 0.1 2.5 3 0 0 3 3 3 0 ArgK protein Bac_DnaA PF00308.13 ETS61770.1 - 0.39 10.3 4.0 6.3 6.3 0.2 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein AAA PF00004.24 ETS61770.1 - 0.43 10.7 3.9 0.43 10.7 0.2 2.7 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Cep57_CLD_2 PF14197.1 ETS61770.1 - 1.5 8.8 7.8 8 6.4 5.5 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 zf-CSL PF05207.8 ETS61771.1 - 5e-25 86.7 1.6 7.7e-25 86.1 1.1 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.1 ETS61771.1 - 0.0028 17.2 0.7 0.0047 16.4 0.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 ETS61771.1 - 0.0095 15.8 0.5 0.017 15.0 0.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_5 PF13719.1 ETS61771.1 - 0.011 15.3 1.0 0.011 15.3 0.7 1.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETS61771.1 - 0.033 13.8 1.2 0.033 13.8 0.8 1.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF164 PF02591.10 ETS61771.1 - 0.074 12.8 0.1 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Putative zinc ribbon domain Ras PF00071.17 ETS61772.1 - 3.5e-55 185.8 0.1 4e-55 185.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS61772.1 - 5.2e-18 65.6 0.0 6.7e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS61772.1 - 2.5e-16 59.3 0.0 3.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS61772.1 - 3.4e-05 23.7 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETS61772.1 - 0.00079 18.6 0.0 0.00097 18.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS61772.1 - 0.0015 18.0 0.1 0.0036 16.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETS61772.1 - 0.0073 15.5 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 ETS61772.1 - 0.054 13.0 0.1 0.088 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS61772.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 ETS61772.1 - 0.14 11.4 0.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Pil1 PF13805.1 ETS61773.1 - 1.1e-09 37.8 0.9 1.1e-09 37.8 0.6 2.2 2 0 0 2 2 2 1 Eisosome component PIL1 IMD PF08397.6 ETS61773.1 - 0.011 15.0 2.6 1.8 7.8 0.4 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain Glyco_hydro_32N PF00251.15 ETS61774.1 - 1.6e-48 165.6 0.0 2.2e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 ETS61774.1 - 9.1e-09 35.5 0.0 2.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 ETS61774.1 - 0.028 14.1 0.4 1.1 9.3 0.1 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat Polysacc_deac_1 PF01522.16 ETS61777.1 - 5.4e-06 26.0 0.0 9.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Claudin_3 PF06653.6 ETS61777.1 - 2.9 7.5 14.5 0.61 9.7 1.7 2.5 2 1 0 2 2 2 0 Tight junction protein, Claudin-like EPSP_synthase PF00275.15 ETS61778.1 - 8.8e-116 386.7 0.1 1.3e-115 386.2 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 ETS61778.1 - 6.6e-96 320.2 0.0 2.3e-95 318.4 0.0 1.9 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 ETS61778.1 - 1.9e-62 210.8 0.0 3.4e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 ETS61778.1 - 1.7e-26 92.9 0.0 1.5e-25 89.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 ETS61778.1 - 4.2e-26 90.8 0.0 1.4e-25 89.1 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ETS61778.1 - 1.4e-09 38.1 0.0 3.8e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 ETS61778.1 - 8.3e-06 25.2 0.1 4.4e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase OCD_Mu_crystall PF02423.10 ETS61778.1 - 0.0056 15.4 0.6 0.11 11.2 0.1 2.4 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family SURF6 PF04935.7 ETS61779.1 - 9.3e-50 168.8 34.0 9.3e-50 168.8 23.6 3.0 3 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 ETS61779.1 - 7.7e-15 54.7 5.5 7.7e-15 54.7 3.8 5.6 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 TFIIA PF03153.8 ETS61779.1 - 0.95 9.2 46.9 0.013 15.4 16.0 2.4 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAP2 PF01569.16 ETS61780.1 - 4.8e-20 71.5 2.6 4.8e-20 71.5 1.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily TRAM_LAG1_CLN8 PF03798.11 ETS61782.1 - 5.9e-42 143.4 21.8 5.9e-42 143.4 15.1 2.7 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 ETS61782.1 - 2.4e-08 33.3 0.2 2.7e-07 29.9 0.0 2.6 3 0 0 3 3 3 1 TRAM1-like protein Fungal_trans PF04082.13 ETS61784.1 - 3.4e-32 111.3 0.0 5.2e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61784.1 - 6e-10 38.8 8.8 9.9e-10 38.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 ETS61786.1 - 3.3e-56 190.6 0.0 4.3e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS61786.1 - 3.7e-37 127.8 0.1 8.5e-37 126.6 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS61786.1 - 2.1e-05 23.5 0.5 0.068 12.0 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS61786.1 - 0.0006 18.8 0.3 0.006 15.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS61786.1 - 0.00081 19.5 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS61786.1 - 0.0013 17.7 0.1 0.0021 17.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS61786.1 - 0.019 14.9 0.6 0.056 13.4 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS61786.1 - 0.039 12.4 0.3 4.7 5.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 ETS61786.1 - 0.043 12.8 0.2 0.085 11.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Metallophos PF00149.23 ETS61787.1 - 5.5e-11 42.2 0.0 3.7e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS61787.1 - 3.5e-05 23.6 0.0 0.00053 19.8 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Phos_pyr_kin PF08543.7 ETS61788.1 - 1.2e-72 244.0 0.0 1.9e-54 184.4 0.0 2.9 2 1 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 ETS61788.1 - 1e-33 116.8 0.2 2.7e-33 115.5 0.0 1.8 2 0 0 2 2 2 1 TENA/THI-4/PQQC family MFS_1 PF07690.11 ETS61788.1 - 1.3e-26 93.1 26.2 1.9e-26 92.6 14.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily PfkB PF00294.19 ETS61788.1 - 0.11 11.5 0.3 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Zn_clus PF00172.13 ETS61791.1 - 0.00046 20.0 8.9 0.00086 19.1 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bul1_C PF04426.7 ETS61791.1 - 0.06 12.5 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 Bul1 C terminus SET PF00856.23 ETS61792.1 - 3.4e-14 53.4 0.0 1.8e-13 51.1 0.0 2.2 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 ETS61792.1 - 2.7e-06 27.3 0.4 8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Nop14 PF04147.7 ETS61792.1 - 1 7.1 31.6 1.7 6.4 21.9 1.2 1 0 0 1 1 1 0 Nop14-like family Steroid_dh PF02544.11 ETS61793.1 - 1.6e-34 118.7 4.6 2.2e-34 118.3 3.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 ETS61793.1 - 0.00014 21.1 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family PEMT PF04191.8 ETS61793.1 - 0.0012 18.9 1.1 0.006 16.6 0.2 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 ETS61793.1 - 0.0014 17.9 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETS61793.1 - 0.0044 17.1 1.2 0.0072 16.4 0.2 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ubiquitin_2 PF14560.1 ETS61793.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain UAE_UbL PF14732.1 ETS61793.1 - 0.033 14.2 0.1 0.073 13.1 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UN_NPL4 PF11543.3 ETS61793.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 YukD PF08817.5 ETS61793.1 - 0.15 12.6 0.1 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Glyco_hydro_20 PF00728.17 ETS61794.1 - 4.4e-28 98.4 0.0 6.1e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain MMS19_N PF14500.1 ETS61795.1 - 3.7e-62 209.9 0.0 6.1e-49 166.6 0.0 3.9 3 1 0 3 3 3 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 ETS61795.1 - 1.2e-45 156.0 0.0 2.3e-44 151.7 0.0 2.8 1 1 1 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 ETS61795.1 - 0.005 16.7 6.8 35 4.8 0.1 7.0 7 0 0 7 7 7 0 HEAT repeat Arm PF00514.18 ETS61795.1 - 0.014 15.2 5.2 5.4 7.0 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETS61795.1 - 0.052 14.0 16.5 13 6.3 0.3 7.9 5 2 2 7 7 7 0 HEAT-like repeat DUF2360 PF10152.4 ETS61795.1 - 3.6 7.8 6.3 17 5.7 4.4 2.2 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) AT_hook PF02178.14 ETS61796.1 - 1.7 8.5 20.8 0.073 12.7 1.8 3.6 3 0 0 3 3 3 0 AT hook motif Mito_fiss_reg PF05308.6 ETS61797.1 - 0.077 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Aminotran_5 PF00266.14 ETS61798.1 - 1.1e-25 90.1 0.0 2.4e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 ETS61798.1 - 3.5e-20 71.9 0.0 8.1e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 ETS61798.1 - 6.3e-15 54.8 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Peptidase_S49 PF01343.13 ETS61799.1 - 2.9e-48 163.5 0.0 1.1e-27 96.6 0.0 3.1 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.18 ETS61799.1 - 0.00015 21.5 4.8 0.00052 19.7 0.0 3.0 4 0 0 4 4 4 1 Clp protease SDH_sah PF01972.11 ETS61799.1 - 0.021 13.6 0.0 0.051 12.3 0.0 1.6 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF3228 PF11539.3 ETS61801.1 - 0.038 13.1 0.8 0.065 12.3 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3228) CCDC-167 PF15188.1 ETS61801.1 - 0.047 13.6 8.7 0.13 12.1 5.5 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Bap31 PF05529.7 ETS61801.1 - 0.42 10.0 10.1 0.98 8.8 0.1 2.5 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like Laminin_II PF06009.7 ETS61801.1 - 0.73 9.5 6.7 0.74 9.5 3.5 1.9 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.6 ETS61801.1 - 0.88 8.1 11.3 10 4.6 8.2 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 ETS61801.1 - 1 9.1 10.1 5.5 6.8 7.0 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 ETS61801.1 - 1.2 7.5 9.6 2.5 6.4 6.7 1.5 1 1 0 1 1 1 0 AAA domain PXA PF02194.10 ETS61801.1 - 1.4 8.4 8.0 0.26 10.8 1.5 2.1 1 1 1 2 2 2 0 PXA domain TPR_MLP1_2 PF07926.7 ETS61801.1 - 1.8 8.2 13.5 14 5.3 0.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 ETS61801.1 - 3.3 7.2 16.9 1.9 8.0 10.1 1.8 1 1 0 1 1 1 0 IncA protein DUF3682 PF12446.3 ETS61801.1 - 3.9 7.7 12.1 0.12 12.6 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3682) zf-C4H2 PF10146.4 ETS61801.1 - 4.6 7.2 9.3 54 3.7 6.5 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein Tup_N PF08581.5 ETS61801.1 - 7.8 6.7 12.6 68 3.7 5.9 3.1 2 2 0 2 2 2 0 Tup N-terminal Sec6 PF06046.8 ETS61802.1 - 8.2e-161 535.9 0.0 1e-160 535.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 MutS_III PF05192.13 ETS61802.1 - 0.0095 15.7 0.0 0.03 14.1 0.0 2.0 1 1 0 1 1 1 1 MutS domain III DUF3832 PF12909.2 ETS61802.1 - 0.052 13.6 0.0 7.1 6.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3832) NPV_P10 PF05531.7 ETS61802.1 - 0.11 12.7 0.6 0.95 9.7 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fungal_trans PF04082.13 ETS61803.1 - 1.9e-25 89.2 0.0 3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61803.1 - 4.6e-07 29.6 7.6 7.5e-07 28.9 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.17 ETS61805.1 - 5.4e-23 81.3 0.0 8.7e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 ETS61805.1 - 1.7e-22 79.4 0.0 1.6e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase MFS_1 PF07690.11 ETS61806.1 - 1.1e-28 99.9 26.5 1.1e-28 99.9 18.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS61806.1 - 4.5e-12 45.2 3.0 4.5e-12 45.2 2.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4385 PF14328.1 ETS61807.1 - 5.4e-54 182.0 0.2 1e-53 181.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) TROVE PF05731.6 ETS61807.1 - 0.058 12.1 1.1 0.075 11.7 0.8 1.1 1 0 0 1 1 1 0 TROVE domain GMC_oxred_N PF00732.14 ETS61808.1 - 3.6e-54 183.9 2.7 2.9e-53 180.9 1.8 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS61808.1 - 1.1e-29 103.6 0.0 2e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS61808.1 - 1.4e-07 30.6 0.1 0.012 14.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS61808.1 - 5.5e-06 26.3 0.0 1.8e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS61808.1 - 2e-05 24.7 0.4 0.23 11.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS61808.1 - 0.00022 20.2 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Endotoxin_mid PF09131.5 ETS61808.1 - 0.00052 19.5 0.9 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 Bacillus thuringiensis delta-Endotoxin, middle domain DAO PF01266.19 ETS61808.1 - 0.0015 17.5 0.7 0.014 14.3 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS61808.1 - 0.002 18.0 0.0 0.0097 15.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS61808.1 - 0.039 13.0 0.3 0.1 11.6 0.1 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 ETS61808.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS61808.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thiolase_N PF00108.18 ETS61808.1 - 0.11 11.4 1.7 1.7 7.5 0.1 2.5 3 0 0 3 3 3 0 Thiolase, N-terminal domain RNA_pol_A_bac PF01000.21 ETS61809.1 - 4.5e-27 94.4 0.0 1.6e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 ETS61809.1 - 1.5e-14 52.8 0.0 2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 ETS61809.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 MIF4G PF02854.14 ETS61810.1 - 1.7e-46 158.3 0.0 1.4e-24 86.7 0.0 3.3 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 ETS61810.1 - 1.6e-12 47.5 0.3 1.6e-12 47.5 0.2 3.7 3 1 1 4 4 4 2 Up-frameshift suppressor 2 ADH_zinc_N PF00107.21 ETS61811.1 - 1.3e-24 86.2 0.0 2.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS61811.1 - 8.1e-06 26.7 0.0 0.00028 21.7 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 ETS61811.1 - 0.079 12.5 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NADHdh_A3 PF14987.1 ETS61813.1 - 0.0023 17.8 0.3 0.0028 17.5 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 CRAL_TRIO PF00650.15 ETS61814.1 - 1.1e-24 86.7 0.0 1.5e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS61814.1 - 1.7e-06 28.0 0.1 4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 ETS61814.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ING PF12998.2 ETS61815.1 - 3.8e-10 39.9 0.4 5.2e-10 39.5 0.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 ETS61815.1 - 8.1e-09 35.0 7.2 1.2e-08 34.4 5.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS61815.1 - 0.036 13.3 2.2 0.064 12.5 1.5 1.4 1 0 0 1 1 1 0 PHD-finger Med4 PF10018.4 ETS61815.1 - 0.072 12.4 0.7 0.11 11.8 0.3 1.3 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CMS1 PF14617.1 ETS61816.1 - 1.2e-51 175.2 6.5 1.3e-25 89.9 0.0 2.3 1 1 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DUF601 PF04642.7 ETS61816.1 - 0.0065 15.8 5.9 0.0065 15.8 4.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF601 Med19 PF10278.4 ETS61816.1 - 0.19 11.4 7.1 0.29 10.8 3.1 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Apc15p PF05841.6 ETS61816.1 - 2.5 8.8 6.9 1.5 9.5 2.4 2.2 2 1 0 2 2 2 0 Apc15p protein Herpes_DNAp_acc PF04929.7 ETS61816.1 - 4.9 6.0 7.7 1.4 7.8 3.1 1.6 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF4451 PF14616.1 ETS61818.1 - 1.6e-29 102.2 0.5 2.6e-29 101.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) BAR_2 PF10455.4 ETS61820.1 - 8.6e-46 156.1 0.5 1.4e-45 155.4 0.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 ETS61820.1 - 2.8e-20 72.8 5.0 5.5e-16 58.7 1.8 2.1 2 0 0 2 2 2 2 BAR domain Telethonin PF09470.5 ETS61820.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Telethonin protein tRNA_NucTran2_2 PF13735.1 ETS61820.1 - 0.022 14.5 2.3 0.084 12.6 1.6 2.1 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative 14-3-3 PF00244.15 ETS61820.1 - 0.025 13.6 1.1 0.038 13.0 0.8 1.2 1 0 0 1 1 1 0 14-3-3 protein Seryl_tRNA_N PF02403.17 ETS61820.1 - 0.032 14.2 4.8 18 5.4 0.0 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phasin PF05597.6 ETS61820.1 - 0.065 12.9 3.6 0.27 11.0 0.0 3.0 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Uds1 PF15456.1 ETS61820.1 - 0.11 12.4 7.7 0.42 10.6 0.0 2.9 2 1 0 2 2 2 0 Up-regulated During Septation DUF16 PF01519.11 ETS61820.1 - 0.16 12.2 1.6 1.7 8.8 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 Atg14 PF10186.4 ETS61820.1 - 0.98 8.3 4.7 0.73 8.7 1.3 2.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 ETS61820.1 - 1.8 8.9 7.1 2.4 8.5 0.2 3.0 2 2 0 2 2 2 0 Spectrin repeat TPR_MLP1_2 PF07926.7 ETS61820.1 - 4.1 7.1 11.6 4.5 7.0 5.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 ETS61820.1 - 6.7 6.6 13.0 16 5.4 0.2 4.1 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding OTCace PF00185.19 ETS61821.1 - 1.1e-41 142.2 0.0 1.9e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 ETS61821.1 - 2e-40 137.7 0.1 3.8e-40 136.8 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Aminotran_1_2 PF00155.16 ETS61821.1 - 7.4e-16 58.0 0.0 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II F-box-like PF12937.2 ETS61824.1 - 0.012 15.2 0.4 0.039 13.6 0.2 1.9 1 0 0 1 1 1 0 F-box-like Ribosomal_L14 PF00238.14 ETS61825.1 - 2.6e-34 117.6 0.0 2.9e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e F-box-like PF12937.2 ETS61826.1 - 0.017 14.8 0.4 0.034 13.8 0.3 1.5 1 0 0 1 1 1 0 F-box-like tRNA-synt_1g PF09334.6 ETS61827.1 - 1.2e-143 478.4 0.0 1.6e-143 478.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETS61827.1 - 2.8e-08 32.2 0.2 0.00032 18.8 0.0 3.8 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETS61827.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DZR PF12773.2 ETS61827.1 - 1.1 9.1 10.1 6.6 6.6 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 ETS61827.1 - 2 8.1 5.9 4.2 7.1 0.5 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Pam16 PF03656.8 ETS61828.1 - 3.5e-18 65.6 0.6 4.7e-17 61.9 0.4 2.1 1 1 0 1 1 1 1 Pam16 Ribosomal_L3 PF00297.17 ETS61829.1 - 6.7e-33 114.1 2.8 1.8e-32 112.7 2.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L3 Gln-synt_C PF00120.19 ETS61830.1 - 3.1e-61 206.7 0.0 3.9e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 ETS61830.1 - 1.1e-18 66.6 0.0 1.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain QCR10 PF09796.4 ETS61831.1 - 5.2e-25 86.8 0.8 6e-25 86.6 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 ETS61831.1 - 0.036 13.7 2.1 0.048 13.3 1.5 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Zn_clus PF00172.13 ETS61832.1 - 4.7e-05 23.2 10.1 7.4e-05 22.5 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 ETS61833.1 - 2e-160 534.0 0.3 2.4e-160 533.8 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 ETS61833.1 - 1e-14 54.3 0.0 1.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 ETS61833.1 - 4.3e-06 26.7 0.0 2.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Aldedh PF00171.17 ETS61834.1 - 9.1e-178 591.3 0.5 1e-177 591.1 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS61834.1 - 7.5e-08 31.4 0.0 1.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) AA_permease_2 PF13520.1 ETS61835.1 - 6.3e-54 183.1 57.7 8.1e-54 182.7 40.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS61835.1 - 1e-17 63.6 51.8 1.8e-17 62.8 35.9 1.3 1 0 0 1 1 1 1 Amino acid permease CENP-I PF07778.6 ETS61836.1 - 7e-20 70.7 0.3 6.5e-16 57.6 0.0 3.5 4 0 0 4 4 4 3 Mis6 TB2_DP1_HVA22 PF03134.14 ETS61837.1 - 1.1e-32 111.6 6.7 1.8e-32 110.9 4.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HAD_2 PF13419.1 ETS61838.1 - 6.2e-28 98.1 0.3 1.2e-27 97.2 0.2 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 ETS61838.1 - 7.7e-16 57.3 0.1 2.9e-07 30.0 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.2 ETS61838.1 - 1.2e-12 47.3 0.2 2.4e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS61838.1 - 1.2e-09 37.6 0.1 3.5e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain Hydrolase_like PF13242.1 ETS61838.1 - 0.032 13.9 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Pectinesterase PF01095.14 ETS61839.1 - 3.1e-30 104.7 0.1 3.5e-29 101.3 0.1 2.0 1 1 0 1 1 1 1 Pectinesterase NAD_binding_10 PF13460.1 ETS61839.1 - 1.9e-22 80.1 0.1 1.4e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETS61839.1 - 2.5e-05 23.8 0.0 0.00094 18.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS61839.1 - 0.083 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Aminotran_1_2 PF00155.16 ETS61840.1 - 9.5e-42 143.2 0.0 1.5e-41 142.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 ETS61840.1 - 0.00096 17.5 0.0 0.0018 16.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETS61840.1 - 0.074 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 ETS61841.1 - 2.9e-12 46.0 0.0 6.2e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61841.1 - 9.7e-06 25.4 12.7 1.7e-05 24.5 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 ETS61842.1 - 4.3e-10 39.5 0.0 8.9e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS61842.1 - 4e-06 27.2 0.0 6.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS61842.1 - 2.2e-05 24.8 0.0 5.1e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS61842.1 - 7.9e-05 22.2 0.0 0.00026 20.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 ETS61842.1 - 0.003 17.1 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 ETS61842.1 - 0.0034 17.9 0.0 0.0053 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA-synt_1 PF00133.17 ETS61843.1 - 2.9e-216 719.1 0.0 1.3e-215 716.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETS61843.1 - 1.3e-37 128.9 0.7 3.2e-37 127.6 0.5 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETS61843.1 - 4.9e-19 68.2 0.3 2e-09 36.6 0.1 4.5 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 ETS61843.1 - 8.6e-12 44.7 4.1 1.2e-07 31.2 0.1 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 ETS61843.1 - 0.0063 15.3 0.0 0.079 11.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 ETS61843.1 - 0.0071 15.4 0.0 0.56 9.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF3502 PF12010.3 ETS61843.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) tRNA-synt_1b PF00579.20 ETS61843.1 - 0.1 11.7 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.16 ETS61843.1 - 0.11 11.0 0.3 2.8 6.5 0.1 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_S8e PF01201.17 ETS61844.1 - 5.9e-49 165.5 2.1 1.1e-48 164.6 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S8e bZIP_1 PF00170.16 ETS61847.1 - 8.3e-09 35.2 14.2 1.4e-08 34.5 9.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS61847.1 - 4.2e-08 32.8 10.2 4.2e-08 32.8 7.1 2.1 1 1 1 2 2 2 1 Basic region leucine zipper Nucleoplasmin PF03066.10 ETS61847.1 - 0.14 11.6 3.4 0.27 10.7 2.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin TSC22 PF01166.13 ETS61847.1 - 0.24 11.3 1.9 0.48 10.4 1.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 ETS61847.1 - 0.62 9.6 9.8 0.075 12.6 3.7 1.9 2 0 0 2 2 2 0 IncA protein Spt5_N PF11942.3 ETS61847.1 - 2.8 8.6 17.2 6.4 7.4 11.3 2.1 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ApoLp-III PF07464.6 ETS61848.1 - 0.0063 16.5 17.9 0.059 13.3 4.2 3.2 2 1 0 3 3 3 2 Apolipophorin-III precursor (apoLp-III) IncA PF04156.9 ETS61848.1 - 1.2 8.7 10.5 6 6.4 3.3 2.9 2 1 1 3 3 3 0 IncA protein MFS_1 PF07690.11 ETS61849.1 - 1.9e-29 102.5 32.2 3.9e-29 101.4 21.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3040 PF11239.3 ETS61849.1 - 0.27 11.3 3.3 2.9 8.0 0.6 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) CDP-OH_P_tran_2 PF08009.6 ETS61849.1 - 0.6 9.9 7.5 0.075 12.7 0.7 2.8 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 SAC3_GANP PF03399.11 ETS61850.1 - 7.1e-54 182.4 0.0 1.1e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TraV PF09676.5 ETS61851.1 - 0.33 11.6 3.5 0.13 12.9 0.5 1.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) PNP_UDP_1 PF01048.15 ETS61852.1 - 9e-24 83.7 0.2 1.2e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Band_7 PF01145.20 ETS61853.1 - 2.8e-24 85.9 4.8 7.2e-24 84.6 3.1 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family tRNA-synt_2b PF00587.20 ETS61854.1 - 2.6e-21 75.9 0.0 5.1e-20 71.7 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FLILHELTA PF10306.4 ETS61854.1 - 3.6e-21 74.9 0.0 1.2e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF4618 PF15397.1 ETS61854.1 - 0.017 14.4 3.8 0.034 13.4 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) tRNA-synt_2d PF01409.15 ETS61854.1 - 0.041 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Hamartin PF04388.7 ETS61854.1 - 0.073 11.7 4.4 0.12 11.0 3.0 1.2 1 0 0 1 1 1 0 Hamartin protein DUF1279 PF06916.8 ETS61854.1 - 0.08 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Fez1 PF06818.10 ETS61854.1 - 0.31 11.0 11.9 0.63 10.0 8.2 1.4 1 0 0 1 1 1 0 Fez1 DNA_topoisoIV PF00521.15 ETS61855.1 - 1.3e-127 426.1 0.0 2.5e-127 425.2 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 ETS61855.1 - 1.3e-35 122.2 1.1 2.9e-35 121.0 0.8 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 ETS61855.1 - 1.8e-14 53.4 0.0 6.5e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 ETS61855.1 - 6.4e-09 35.5 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Asn_synthase PF00733.16 ETS61856.1 - 3e-49 167.8 0.0 7.1e-49 166.6 0.0 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 ETS61856.1 - 6.3e-10 38.8 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETS61856.1 - 2.5e-07 30.7 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.15 ETS61856.1 - 0.089 12.2 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 PP-loop family Chs3p PF12271.3 ETS61857.1 - 3.2e-113 377.5 16.7 3.7e-113 377.3 11.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit WD40 PF00400.27 ETS61858.1 - 2.7e-47 157.0 10.5 7.5e-10 38.3 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETS61858.1 - 2.8e-09 35.6 3.5 0.0004 18.6 0.0 4.4 3 2 1 4 4 4 3 Nucleoporin Nup120/160 DUF869 PF05911.6 ETS61858.1 - 0.003 15.8 0.1 0.0042 15.4 0.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 ETS61858.1 - 0.065 13.0 5.1 0.12 12.2 3.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.1 ETS61859.1 - 2.2e-16 60.1 2.3 6e-16 58.7 0.0 2.8 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 ETS61859.1 - 2.5e-09 37.4 0.0 5.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETS61859.1 - 1.2e-08 34.8 0.0 2.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS61859.1 - 1.2e-07 31.8 1.4 1.2e-07 31.8 1.0 3.7 3 2 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 ETS61859.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 ETS61859.1 - 0.0027 17.4 0.0 0.0083 15.8 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 ETS61859.1 - 0.0088 15.9 0.5 0.035 13.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain KH_1 PF00013.24 ETS61860.1 - 4.5e-05 23.0 0.6 9.4e-05 21.9 0.4 1.5 1 0 0 1 1 1 1 KH domain Choline_transpo PF04515.7 ETS61861.1 - 1e-34 119.8 13.9 1.5e-22 79.8 0.1 2.5 3 0 0 3 3 3 2 Plasma-membrane choline transporter PCI PF01399.22 ETS61862.1 - 9.4e-07 29.1 0.1 1.9e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 PCI domain COG2 PF06148.6 ETS61862.1 - 0.016 15.0 1.0 0.033 14.0 0.7 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ParB PF08775.5 ETS61862.1 - 0.15 12.3 1.7 0.31 11.3 1.2 1.4 1 0 0 1 1 1 0 ParB family Pkinase PF00069.20 ETS61863.1 - 1.6e-59 201.1 0.0 7.2e-59 199.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61863.1 - 1.1e-27 96.7 0.0 3.6e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS61863.1 - 4.5e-07 29.1 0.0 8e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS61863.1 - 0.0096 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS61863.1 - 0.055 12.2 0.1 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 PA_decarbox PF05870.6 ETS61864.1 - 1.3e-09 37.7 0.1 1.5e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) ParA PF10609.4 ETS61865.1 - 1.8e-33 114.2 0.0 2.9e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETS61865.1 - 6.5e-11 42.0 0.0 1.6e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETS61865.1 - 2.3e-06 27.6 0.0 2.1e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 ETS61865.1 - 6.8e-06 25.3 1.1 8.1e-05 21.7 0.2 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase zf-C4_ClpX PF06689.8 ETS61865.1 - 0.00039 19.8 0.4 0.00069 19.0 0.3 1.4 1 0 0 1 1 1 1 ClpX C4-type zinc finger MipZ PF09140.6 ETS61865.1 - 0.0032 16.5 0.0 0.0097 15.0 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 ETS61865.1 - 0.0032 17.0 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS61865.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cache_3 PF14827.1 ETS61865.1 - 0.049 13.5 0.0 0.049 13.5 0.0 2.3 3 0 0 3 3 3 0 Sensory domain of two-component sensor kinase DUF258 PF03193.11 ETS61865.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IBN_N PF03810.14 ETS61865.1 - 0.1 12.5 0.3 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain EMP24_GP25L PF01105.19 ETS61867.1 - 4e-47 160.3 0.0 5e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Voltage_CLC PF00654.15 ETS61868.1 - 2.3e-91 306.4 28.4 4.9e-91 305.3 19.7 1.5 1 0 0 1 1 1 1 Voltage gated chloride channel Pro_isomerase PF00160.16 ETS61868.1 - 4.9e-32 111.2 0.0 8.6e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 ETS61868.1 - 9.6e-16 57.1 0.0 2.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS61868.1 - 4.2e-11 42.6 0.1 1.2e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.23 ETS61868.1 - 2e-08 33.8 0.1 1.2e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 CBS domain RRM_5 PF13893.1 ETS61868.1 - 6.5e-07 29.1 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 ETS61868.1 - 0.025 14.4 6.7 0.033 14.1 0.1 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MutL_C PF08676.6 ETS61870.1 - 2.6e-07 30.3 0.2 3.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain PCI PF01399.22 ETS61874.1 - 4e-09 36.7 0.0 7.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain TIP120 PF08623.5 ETS61875.1 - 1.1e-48 165.0 4.0 1.2e-48 164.8 0.0 3.1 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 ETS61875.1 - 1.3e-13 51.0 35.7 0.00013 22.2 0.1 9.9 6 4 4 10 10 10 8 HEAT repeats HEAT PF02985.17 ETS61875.1 - 2.2e-08 33.5 30.9 1 9.5 0.1 12.3 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 ETS61875.1 - 3.8e-06 27.2 44.3 0.026 15.0 0.1 12.5 11 2 3 14 14 14 4 HEAT-like repeat Cohesin_HEAT PF12765.2 ETS61875.1 - 0.0069 16.3 2.0 0.036 14.0 0.1 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 ETS61875.1 - 0.007 16.2 7.5 0.43 10.4 0.0 5.0 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 ETS61875.1 - 0.036 13.0 3.7 0.32 9.9 0.1 3.9 4 2 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain PHO4 PF01384.15 ETS61876.1 - 2e-114 381.6 16.4 3e-114 381.0 11.4 1.3 1 0 0 1 1 1 1 Phosphate transporter family KR PF08659.5 ETS61876.1 - 0.033 13.8 0.2 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 KR domain Y2_Tnp PF04986.8 ETS61878.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative transposase MFS_1 PF07690.11 ETS61879.1 - 2.7e-32 111.8 41.5 7.2e-30 103.8 17.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TraL PF07178.6 ETS61879.1 - 1.1 9.3 4.7 1.4 8.9 0.3 3.1 3 0 0 3 3 3 0 TraL protein DUF2427 PF10348.4 ETS61879.1 - 1.7 8.2 6.6 0.28 10.7 0.7 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) BLVR PF06375.6 ETS61882.1 - 0.025 14.3 1.0 0.057 13.2 0.7 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) E1-E2_ATPase PF00122.15 ETS61883.1 - 1.1e-58 197.9 0.2 3.3e-58 196.4 0.1 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS61883.1 - 5.9e-46 156.2 6.6 5.9e-46 156.2 4.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS61883.1 - 8.7e-27 94.9 0.0 6.1e-26 92.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS61883.1 - 6.1e-18 64.5 0.1 1.4e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS61883.1 - 1.1e-13 51.8 0.1 6.9e-13 49.1 0.1 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS61883.1 - 9.8e-08 31.3 0.3 2.1e-06 27.1 0.1 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS61883.1 - 0.00055 19.6 0.3 0.012 15.2 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phosphodiest PF01663.17 ETS61884.1 - 9.8e-08 31.6 2.2 2.2e-07 30.5 1.5 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ETS61884.1 - 0.019 14.3 2.4 0.032 13.6 1.7 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily SUR7 PF06687.7 ETS61885.1 - 8.2e-21 74.5 4.1 1.2e-20 74.0 2.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 ETS61885.1 - 0.003 17.2 4.8 0.003 17.2 3.3 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4407 PF14362.1 ETS61885.1 - 0.018 14.0 0.9 0.026 13.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RAMP PF04901.8 ETS61885.1 - 0.019 14.6 0.2 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 Receptor activity modifying family RseC_MucC PF04246.7 ETS61885.1 - 0.03 13.9 0.3 0.03 13.9 0.2 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC FUSC_2 PF13515.1 ETS61885.1 - 0.047 13.6 7.6 0.014 15.3 2.5 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Clc-like PF07062.7 ETS61885.1 - 0.28 10.4 7.2 0.019 14.2 1.3 1.7 2 0 0 2 2 2 0 Clc-like Claudin_3 PF06653.6 ETS61885.1 - 0.72 9.5 5.1 0.17 11.5 0.7 1.8 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Amastin PF07344.6 ETS61885.1 - 3.7 7.1 8.5 0.73 9.4 2.7 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein Ribosomal_S7 PF00177.16 ETS61886.1 - 1.6e-35 121.8 0.4 2.4e-35 121.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Myb_DNA-binding PF00249.26 ETS61887.1 - 6e-22 77.4 0.6 1.2e-11 44.5 0.1 5.4 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS61887.1 - 8.1e-16 57.8 0.0 8.9e-07 28.9 0.0 4.6 3 1 2 5 5 5 3 Myb-like DNA-binding domain Peptidase_S10 PF00450.17 ETS61888.1 - 3.1e-98 329.6 0.0 4.2e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CN_hydrolase PF00795.17 ETS61889.1 - 5.5e-18 64.9 0.0 7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4588 PF15251.1 ETS61890.1 - 5.5e-06 26.5 9.9 5.5e-06 26.5 6.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) IPP-2 PF04979.9 ETS61891.1 - 3.9e-14 53.0 3.4 6.1e-07 29.7 1.6 2.2 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Corona_nucleoca PF00937.13 ETS61891.1 - 0.068 12.1 3.3 0.1 11.5 2.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CDC27 PF09507.5 ETS61891.1 - 0.25 10.5 5.5 0.39 9.8 3.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DLIC PF05783.6 ETS61892.1 - 4.7e-51 173.9 9.8 1.4e-26 93.2 0.0 6.7 5 1 2 7 7 7 6 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 ETS61892.1 - 0.00011 22.2 0.5 0.0045 17.0 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 ETS61892.1 - 0.0022 18.4 0.1 0.022 15.2 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein MCM PF00493.18 ETS61892.1 - 0.0036 16.1 0.2 0.0066 15.2 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MMR_HSR1 PF01926.18 ETS61892.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS61892.1 - 0.023 14.1 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 ETS61892.1 - 0.035 13.6 0.2 0.091 12.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2813 PF11398.3 ETS61892.1 - 0.068 12.2 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Pkr1 PF08636.5 ETS61893.1 - 8.9e-16 57.7 2.9 1.2e-15 57.2 2.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 PRA1 PF03208.14 ETS61893.1 - 0.0014 17.9 0.9 0.0016 17.8 0.6 1.1 1 0 0 1 1 1 1 PRA1 family protein UPF0154 PF03672.8 ETS61893.1 - 0.026 14.1 0.8 0.079 12.5 0.5 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3329 PF11808.3 ETS61893.1 - 0.058 13.4 1.3 3.9 7.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF3619 PF12279.3 ETS61894.1 - 6.5 6.8 8.3 0.97 9.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) DUF676 PF05057.9 ETS61897.1 - 1.7e-31 109.2 0.0 8.2e-31 106.9 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 ETS61897.1 - 1.2e-06 28.2 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS61897.1 - 0.0011 18.8 5.2 0.0024 17.8 3.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS61897.1 - 0.038 13.2 0.0 0.13 11.5 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family ABC_tran PF00005.22 ETS61898.1 - 6.3e-48 162.5 0.0 1.1e-23 84.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 ETS61898.1 - 2.5e-20 72.7 29.8 1.6e-12 47.1 2.7 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 ETS61898.1 - 3e-16 60.2 1.2 6.3e-06 26.3 0.0 4.8 5 1 0 5 5 5 3 AAA domain SMC_N PF02463.14 ETS61898.1 - 1.7e-05 24.1 0.1 0.73 9.0 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS61898.1 - 0.00011 21.6 1.7 0.01 15.3 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 ETS61898.1 - 0.029 13.8 1.9 2.5 7.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 ETS61898.1 - 0.14 12.4 1.0 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 ETS61898.1 - 1.1 8.4 1.5 3 7.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 ETS61898.1 - 1.5 8.5 5.7 2.8 7.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 CN_hydrolase PF00795.17 ETS61899.1 - 2.8e-28 98.5 0.0 4.2e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LSM PF01423.17 ETS61901.1 - 3e-05 23.4 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 ETS61901.1 - 0.0055 16.5 0.1 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain NMO PF03060.10 ETS61902.1 - 5.6e-71 239.3 0.1 6.6e-71 239.1 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 ETS61902.1 - 8.5e-11 41.3 0.3 1.4e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 ETS61902.1 - 2.5e-05 23.2 1.1 3.8e-05 22.6 0.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 ETS61902.1 - 0.0049 16.1 0.7 0.024 13.8 0.1 2.1 2 0 0 2 2 2 1 PcrB family NanE PF04131.9 ETS61902.1 - 0.15 11.0 0.9 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase AAA_18 PF13238.1 ETS61905.1 - 1.1e-21 77.5 0.0 4.1e-21 75.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS61905.1 - 7.4e-11 42.9 0.0 1.4e-10 41.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ETS61905.1 - 0.0013 18.6 2.8 0.0038 17.1 1.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS61905.1 - 0.0078 16.2 0.0 0.0092 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 ETS61905.1 - 0.019 14.1 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 ETS61905.1 - 0.023 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS61905.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF927 PF06048.6 ETS61905.1 - 0.03 13.5 0.4 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF927) AAA_10 PF12846.2 ETS61905.1 - 0.03 13.7 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SKI PF01202.17 ETS61905.1 - 0.034 14.0 0.1 0.6 9.9 0.0 2.2 2 1 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.1 ETS61905.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Thymidylate_kin PF02223.12 ETS61905.1 - 0.041 13.2 0.0 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_33 PF13671.1 ETS61905.1 - 0.088 12.6 2.7 2.5 7.9 0.6 2.7 2 1 0 2 2 2 0 AAA domain ADK PF00406.17 ETS61905.1 - 0.1 12.4 0.1 5.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase NTPase_1 PF03266.10 ETS61905.1 - 0.13 11.9 0.8 0.35 10.5 0.1 2.0 3 0 0 3 3 3 0 NTPase FtsK_SpoIIIE PF01580.13 ETS61905.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 ETS61905.1 - 0.16 12.2 0.1 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 ETS61906.1 - 4.9e-107 357.1 0.6 6.8e-107 356.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 ETS61906.1 - 2.2e-07 30.8 0.0 4.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS61906.1 - 0.00018 20.9 0.1 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 ETS61906.1 - 0.00067 20.4 2.6 0.002 18.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.18 ETS61906.1 - 0.00077 19.3 6.3 0.051 13.3 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 ETS61906.1 - 0.0011 18.1 0.4 0.0047 16.1 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 ETS61906.1 - 0.0015 18.9 0.3 0.0048 17.3 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 ETS61906.1 - 0.0015 18.0 0.2 0.0033 16.9 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gasdermin PF04598.7 ETS61906.1 - 0.0031 16.3 1.5 0.0043 15.8 1.0 1.1 1 0 0 1 1 1 1 Gasdermin family AIG1 PF04548.11 ETS61906.1 - 0.0038 16.3 0.0 0.0087 15.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 ETS61906.1 - 0.0039 17.0 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ETS61906.1 - 0.0048 16.8 2.1 0.046 13.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETS61906.1 - 0.0051 16.9 0.7 0.016 15.3 0.0 2.1 3 1 0 3 3 3 1 AAA domain IIGP PF05049.8 ETS61906.1 - 0.01 14.6 0.9 0.023 13.5 0.1 1.9 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MobB PF03205.9 ETS61906.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 ETS61906.1 - 0.024 14.0 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS61906.1 - 0.03 14.6 0.4 0.11 12.8 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 ETS61906.1 - 0.066 13.1 1.7 0.076 12.9 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 ETS61906.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ras PF00071.17 ETS61906.1 - 0.075 12.4 0.3 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Ras family NACHT PF05729.7 ETS61906.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 ETS61906.1 - 0.11 12.2 0.1 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 ETS61906.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS61906.1 - 0.13 12.5 4.9 0.21 11.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 ETS61906.1 - 2.7 7.7 7.3 2 8.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 TPK_B1_binding PF04265.9 ETS61907.1 - 1.4e-19 69.5 0.0 2.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Lactamase_B_2 PF12706.2 ETS61907.1 - 3.6e-19 69.0 0.0 8.5e-19 67.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TPK_catalytic PF04263.11 ETS61907.1 - 4.5e-19 68.2 0.0 8.8e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Lactamase_B PF00753.22 ETS61907.1 - 1.5e-11 44.3 0.1 5.6e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 ETS61907.1 - 0.31 9.9 0.1 0.5 9.2 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Cortex-I_coil PF09304.5 ETS61908.1 - 1.2e-32 112.1 19.7 1.2e-32 112.1 13.7 1.9 2 0 0 2 2 2 1 Cortexillin I, coiled coil Spindle_Spc25 PF08234.7 ETS61908.1 - 6.5e-21 74.1 0.1 1.5e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 ETS61908.1 - 0.0028 16.3 12.1 0.0042 15.7 8.1 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein Hrs_helical PF12210.3 ETS61908.1 - 0.013 15.6 8.0 0.5 10.6 0.7 3.1 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CALCOCO1 PF07888.6 ETS61908.1 - 0.031 12.5 13.4 0.039 12.2 9.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Snapin_Pallidin PF14712.1 ETS61908.1 - 0.14 12.4 8.7 0.055 13.7 2.7 2.6 2 2 0 2 2 2 0 Snapin/Pallidin TPR_MLP1_2 PF07926.7 ETS61908.1 - 1.8 8.3 22.2 1.5 8.5 10.6 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 ETS61908.1 - 2.1 7.8 20.3 0.18 11.3 6.9 2.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 ETS61908.1 - 2.8 8.0 11.4 15 5.7 6.2 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 ETS61908.1 - 3.5 7.2 15.9 0.38 10.3 7.8 1.8 2 0 0 2 2 2 0 Mnd1 family DUF342 PF03961.8 ETS61908.1 - 6 5.1 13.3 0.65 8.3 6.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Pkinase PF00069.20 ETS61909.1 - 1.9e-56 191.1 0.0 6.2e-56 189.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS61909.1 - 2.9e-27 95.3 0.0 4.2e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS61909.1 - 7e-07 28.4 0.0 0.00043 19.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETS61909.1 - 0.0034 17.1 0.1 0.055 13.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS61909.1 - 0.026 13.5 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 ETS61909.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-4CXXC_R1 PF10497.4 ETS61910.1 - 2.1e-15 56.7 12.5 4.2e-15 55.7 8.7 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 TF_Zn_Ribbon PF08271.7 ETS61910.1 - 0.056 12.7 4.5 0.16 11.3 3.1 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding AT_hook PF02178.14 ETS61910.1 - 0.79 9.6 19.2 3.1 7.7 3.6 3.2 2 0 0 2 2 2 0 AT hook motif Sporozoite_P67 PF05642.6 ETS61910.1 - 1.4 6.6 13.6 0.64 7.8 3.7 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MAPEG PF01124.13 ETS61911.1 - 5.2e-27 93.9 2.8 6.1e-27 93.7 1.9 1.0 1 0 0 1 1 1 1 MAPEG family Ferrochelatase PF00762.14 ETS61912.1 - 9e-104 346.8 0.0 1.2e-103 346.4 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Synaptobrevin PF00957.16 ETS61912.1 - 8.7e-30 102.1 2.4 1.5e-29 101.4 1.6 1.3 1 0 0 1 1 1 1 Synaptobrevin CbiX PF01903.12 ETS61912.1 - 0.0011 19.0 0.1 1.9 8.6 0.0 2.7 2 0 0 2 2 2 2 CbiX UQ_con PF00179.21 ETS61913.1 - 7.3e-27 93.5 0.0 9e-27 93.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS61913.1 - 6.2e-05 22.7 0.0 7.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 ETS61913.1 - 0.0041 16.8 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 ETS61913.1 - 0.0058 16.5 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain HECT PF00632.20 ETS61914.1 - 3.1e-97 325.5 0.0 4e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fructosamin_kin PF03881.9 ETS61915.1 - 4.5e-45 153.8 0.3 1.8e-42 145.3 0.2 2.1 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 ETS61915.1 - 8.4e-09 35.5 0.7 1.4e-08 34.7 0.5 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FH2 PF02181.18 ETS61916.1 - 0.32 9.8 13.9 0.55 9.0 2.9 2.2 1 1 0 2 2 2 0 Formin Homology 2 Domain DUF3584 PF12128.3 ETS61916.1 - 0.42 7.8 28.3 0.58 7.4 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 ETS61916.1 - 5.1 7.0 31.6 8.9 6.2 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ApoO PF09769.4 ETS61916.1 - 5.9 6.5 6.2 2.8 7.6 0.2 3.0 2 1 2 4 4 4 0 Apolipoprotein O AAA_13 PF13166.1 ETS61916.1 - 6.3 5.1 18.6 11 4.3 12.9 1.3 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.20 ETS61917.1 - 1.8e-33 114.2 0.2 3e-17 62.3 0.0 3.3 2 1 0 2 2 2 2 Bromodomain Abhydro_lipase PF04083.11 ETS61918.1 - 1.6e-15 56.2 0.0 2.6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 ETS61918.1 - 9.9e-06 25.3 0.2 2.5e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS61918.1 - 0.031 13.8 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Rgp1 PF08737.5 ETS61919.1 - 1.8e-90 304.0 0.0 2.7e-90 303.4 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 ETS61919.1 - 3.5e-05 23.9 0.0 0.019 15.0 0.0 3.0 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS61919.1 - 0.0016 18.3 0.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF1537 PF07005.6 ETS61920.1 - 0.2 11.2 9.0 0.034 13.8 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF1537 Cupin_2 PF07883.6 ETS61921.1 - 2.3e-05 23.7 0.1 4.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Cupin domain DUF1498 PF07385.7 ETS61921.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) FMO-like PF00743.14 ETS61922.1 - 9e-44 149.5 0.0 3.2e-43 147.7 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS61922.1 - 3.7e-23 82.6 0.1 9.3e-23 81.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS61922.1 - 6.5e-15 55.5 0.0 2.4e-12 47.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS61922.1 - 2.4e-10 40.2 0.0 5.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS61922.1 - 2.8e-10 40.1 0.0 1.8e-06 27.7 0.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 ETS61922.1 - 4e-10 39.1 0.1 7.4e-08 31.6 0.0 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS61922.1 - 5.9e-08 33.0 0.3 0.0006 20.1 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS61922.1 - 8.4e-07 28.2 0.0 2.6e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 ETS61922.1 - 8.9e-07 28.3 0.0 0.0029 16.7 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 ETS61922.1 - 7e-06 24.7 0.1 0.018 13.5 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 ETS61922.1 - 0.00049 19.2 0.0 0.0011 18.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 ETS61922.1 - 0.00084 18.2 0.5 0.7 8.6 0.0 3.1 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_10 PF13460.1 ETS61922.1 - 0.00086 19.3 0.9 0.51 10.3 0.0 3.3 4 0 0 4 4 3 1 NADH(P)-binding Lycopene_cycl PF05834.7 ETS61922.1 - 0.0034 16.3 0.0 0.88 8.4 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 ETS61922.1 - 0.0037 17.5 0.0 2.4 8.4 0.0 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 ETS61922.1 - 0.0048 16.2 0.3 0.013 14.9 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 ETS61922.1 - 0.0086 16.1 0.0 1 9.4 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 ETS61922.1 - 0.027 13.3 0.1 0.15 10.9 0.1 2.0 1 1 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 ETS61922.1 - 0.076 12.0 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 ETS61922.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 ETS61922.1 - 0.13 12.2 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 ETS61922.1 - 0.15 11.8 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FF PF01846.14 ETS61923.1 - 1.3e-29 101.9 6.5 1.2e-06 28.3 0.0 6.7 5 2 0 5 5 5 5 FF domain WW PF00397.21 ETS61923.1 - 1.4e-07 31.2 1.3 1.4e-07 31.2 0.9 2.5 2 0 0 2 2 2 1 WW domain DUF3752 PF12572.3 ETS61924.1 - 8.8e-14 51.8 51.2 2.4e-11 43.9 12.8 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3752) Polyketide_cyc2 PF10604.4 ETS61925.1 - 7.1e-12 45.6 0.0 8.9e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 ETS61925.1 - 0.044 13.7 0.0 0.059 13.3 0.0 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Acetate_kinase PF00871.12 ETS61926.1 - 2.3e-76 256.8 0.0 2.6e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.5 ETS61927.1 - 1.5e-124 415.4 0.0 2.9e-124 414.4 0.0 1.4 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 ETS61927.1 - 9.3e-56 188.2 0.0 2.1e-55 187.0 0.0 1.6 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 ETS61927.1 - 3.1e-50 170.4 0.0 6.3e-50 169.4 0.0 1.5 1 1 0 1 1 1 1 XFP C-terminal domain Pyr_redox_3 PF13738.1 ETS61927.1 - 1.3e-27 97.2 1.0 1.1e-26 94.1 0.1 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS61927.1 - 3.6e-12 45.8 2.4 8.8e-10 38.0 1.6 3.2 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS61927.1 - 1.1e-10 41.4 0.1 7e-10 38.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 ETS61927.1 - 3.6e-09 35.3 0.1 8.2e-09 34.1 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 ETS61927.1 - 0.00018 21.2 0.2 0.045 13.5 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS61927.1 - 0.00029 20.7 0.0 0.056 13.3 0.0 2.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS61927.1 - 0.0019 17.3 0.1 0.0048 16.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 ETS61927.1 - 0.0034 16.2 0.0 0.13 11.1 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 ETS61927.1 - 0.0079 15.0 0.1 2.1 7.1 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS61927.1 - 0.0099 14.9 0.0 0.0099 14.9 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Head-tail_con PF12236.3 ETS61927.1 - 0.14 10.5 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein HI0933_like PF03486.9 ETS61927.1 - 0.3 9.4 0.2 0.52 8.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Amidase PF01425.16 ETS61929.1 - 1.8e-78 264.3 0.0 2.4e-70 237.5 0.0 2.1 2 0 0 2 2 2 2 Amidase DUF4579 PF15158.1 ETS61930.1 - 0.18 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) PBP1_TM PF14812.1 ETS61930.1 - 3.5 8.0 8.1 2.1 8.7 1.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOC3p PF07540.6 ETS61931.1 - 7.2e-22 77.4 0.0 2.1e-20 72.8 0.0 2.8 1 1 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 ETS61931.1 - 1.3e-16 60.4 0.2 4.9e-16 58.6 0.2 2.0 1 0 0 1 1 1 1 CBF/Mak21 family DnaJ PF00226.26 ETS61932.1 - 7.5e-15 54.4 0.0 1.9e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 ETS61933.1 - 6.8e-13 48.3 2.9 7.3e-13 48.2 1.2 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 ETS61933.1 - 1.9e-11 43.9 14.3 1.9e-11 43.9 9.9 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 ETS61933.1 - 0.00069 19.3 0.1 0.00069 19.3 0.1 2.4 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Tetraspannin PF00335.15 ETS61934.1 - 0.26 10.5 4.2 8.6 5.5 1.4 2.2 2 0 0 2 2 2 0 Tetraspanin family Abhydrolase_1 PF00561.15 ETS61935.1 - 5.8e-25 88.1 3.4 3.6e-19 69.2 1.9 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold AAA_23 PF13476.1 ETS61936.1 - 6.9e-20 72.2 0.0 6.9e-20 72.2 0.0 4.2 4 1 1 5 5 5 1 AAA domain SMC_N PF02463.14 ETS61936.1 - 2.1e-19 69.6 0.0 4.7e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS61936.1 - 5.4e-08 33.1 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS61936.1 - 0.0016 17.9 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 ETS61936.1 - 0.0096 15.0 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.1 ETS61936.1 - 0.16 10.3 45.8 0.38 9.1 0.0 5.0 3 2 1 4 4 4 0 AAA domain Seadorna_VP6 PF07407.6 ETS61936.1 - 4.8 5.8 6.0 8.3 5.0 4.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP6 protein Reo_sigmaC PF04582.7 ETS61936.1 - 5.7 6.0 6.0 12 4.9 0.2 3.5 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Glyco_hydro_10 PF00331.15 ETS61937.1 - 7.9e-103 343.8 0.0 9.1e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 ETS61937.1 - 0.025 14.1 0.1 0.093 12.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) Cellulase-like PF12876.2 ETS61937.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like MaoC_dehydratas PF01575.14 ETS61938.1 - 6.6e-10 38.4 0.0 3.6e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain p450 PF00067.17 ETS61939.1 - 2.3e-62 211.0 0.0 3.4e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 ETS61939.1 - 0.00037 20.1 1.1 0.00037 20.1 0.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS61939.1 - 0.0028 17.2 0.2 0.0088 15.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain LIP PF03583.9 ETS61940.1 - 2e-55 188.0 0.1 2.9e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 ETS61940.1 - 0.024 13.8 0.1 2.8 7.1 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans_2 PF11951.3 ETS61941.1 - 7.6e-11 41.2 0.4 3e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61941.1 - 1.4e-07 31.3 9.3 3.3e-07 30.0 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 ETS61943.1 - 3.1e-43 148.0 0.0 4.5e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 ETS61943.1 - 0.029 13.6 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase peroxidase PF00141.18 ETS61944.1 - 4.9e-85 284.6 0.0 6.7e-45 153.3 0.0 2.2 2 0 0 2 2 2 2 Peroxidase AA_permease_2 PF13520.1 ETS61945.1 - 6.1e-45 153.5 47.2 7.9e-45 153.1 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS61945.1 - 4.7e-17 61.4 41.1 4.7e-17 61.4 28.5 2.0 2 0 0 2 2 2 2 Amino acid permease Cu_amine_oxid PF01179.15 ETS61946.1 - 2.5e-160 533.7 0.0 3e-160 533.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 ETS61946.1 - 1.7e-08 34.3 0.2 3.6e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 ETS61946.1 - 0.0043 17.0 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans PF04082.13 ETS61947.1 - 4.6e-17 61.7 0.3 1.1e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS61947.1 - 1e-08 34.9 15.2 8.6e-06 25.8 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS61947.1 - 8.9e-07 28.8 12.5 0.0097 16.1 3.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.13 ETS61947.1 - 1e-06 28.5 8.9 1e-06 28.5 6.2 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 ETS61947.1 - 0.0033 17.5 3.7 0.46 10.7 1.2 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS61947.1 - 0.0047 17.0 6.3 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 ETS61947.1 - 0.035 14.3 11.5 0.3 11.4 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETS61947.1 - 0.11 12.4 18.7 0.063 13.1 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.6 ETS61947.1 - 0.21 11.3 0.9 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger CENP-B_dimeris PF09026.5 ETS61947.1 - 0.3 11.3 9.2 0.045 13.9 3.3 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Aldedh PF00171.17 ETS61948.1 - 2.5e-144 481.0 0.0 2.9e-144 480.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS61948.1 - 4.5e-07 28.9 0.0 1.6e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 ETS61949.1 - 1.4e-05 23.6 0.2 2.6e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4336 PF14234.1 ETS61949.1 - 0.036 13.2 0.3 0.071 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) LigB PF02900.13 ETS61950.1 - 1.2e-26 93.3 0.0 1.4e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Creatininase PF02633.9 ETS61950.1 - 0.058 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase Peptidase_S15 PF02129.13 ETS61952.1 - 8.6e-38 130.3 0.6 1.4e-37 129.6 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS61952.1 - 3.2e-26 92.5 0.1 4.6e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 ETS61952.1 - 0.00012 21.8 0.1 0.00045 19.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS61952.1 - 0.00013 21.9 0.2 0.00027 20.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 ETS61953.1 - 6e-13 48.5 0.2 4.5e-12 45.6 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS61953.1 - 1.2e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS61953.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS61953.1 - 0.015 14.2 1.2 0.048 12.5 0.2 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS61953.1 - 0.027 14.2 0.1 0.41 10.4 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS61953.1 - 0.055 12.3 0.1 0.12 11.2 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 ETS61953.1 - 0.08 13.3 0.4 0.28 11.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS61953.1 - 0.15 10.6 0.3 5.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_1 PF00232.13 ETS61954.1 - 5.7e-104 347.8 0.0 8.8e-104 347.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.13 ETS61954.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) FAA_hydrolase PF01557.13 ETS61955.1 - 8.7e-40 136.4 0.0 1.2e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 ETS61955.1 - 2.4e-24 85.3 0.1 4.4e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.11 ETS61956.1 - 2.3e-25 89.0 30.7 3.6e-13 48.9 5.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS61956.1 - 6.6e-05 21.6 6.6 0.0098 14.5 1.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 ETS61956.1 - 0.00068 18.2 0.5 0.00068 18.2 0.3 2.2 2 2 0 2 2 2 1 Vacuole effluxer Atg22 like Claudin_3 PF06653.6 ETS61956.1 - 0.059 13.0 2.9 0.44 10.2 0.1 2.4 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Fungal_trans PF04082.13 ETS61957.1 - 2.2e-08 33.3 0.0 3.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS61957.1 - 0.0022 17.8 6.7 0.0082 16.0 4.6 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_hydroxylase PF04116.8 ETS61958.1 - 3.6e-14 53.1 9.3 3.6e-14 53.1 6.5 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Thioredoxin_8 PF13905.1 ETS61958.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glyco_transf_28 PF03033.15 ETS61959.1 - 0.00084 19.1 0.0 0.0021 17.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS61959.1 - 0.027 13.0 0.0 0.12 10.8 0.0 1.9 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Tri3 PF07428.6 ETS61961.1 - 0.01 14.5 0.3 0.018 13.7 0.2 1.3 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 MFS_1 PF07690.11 ETS61962.1 - 1.4e-35 122.6 51.6 1.4e-35 122.6 35.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS61962.1 - 1.1e-12 47.2 8.2 1.1e-12 47.2 5.7 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.8 ETS61962.1 - 9.2e-08 30.7 20.3 1.2e-07 30.3 14.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.11 ETS61962.1 - 6.6 4.7 5.5 2.1 6.3 1.6 1.7 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Transferase PF02458.10 ETS61963.1 - 0.0026 16.2 0.0 0.43 8.9 0.0 2.3 2 0 0 2 2 2 2 Transferase family Mu-like_Com PF10122.4 ETS61964.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com HEAT_2 PF13646.1 ETS61965.1 - 0.00013 22.1 15.7 0.0052 17.0 0.5 4.9 5 0 0 5 5 5 2 HEAT repeats TPR_19 PF14559.1 ETS61965.1 - 0.015 15.6 3.2 0.73 10.2 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peroxidase_2 PF01328.12 ETS61966.1 - 5.4e-16 58.1 0.0 8.3e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 ADC PF06314.6 ETS61967.1 - 3.9e-16 59.1 0.1 7.5e-16 58.1 0.1 1.4 2 0 0 2 2 2 1 Acetoacetate decarboxylase (ADC) Cupin_2 PF07883.6 ETS61967.1 - 9.1e-05 21.8 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Zip PF02535.17 ETS61968.1 - 1.3e-32 113.0 20.9 1.3e-32 113.0 14.5 2.8 2 1 0 2 2 2 1 ZIP Zinc transporter DUF4514 PF14986.1 ETS61968.1 - 1.8 8.4 6.4 0.29 10.9 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) DUF3980 PF13140.1 ETS61968.1 - 3.3 8.0 10.9 0.28 11.4 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3980) DUF2061 PF09834.4 ETS61968.1 - 9.1 6.5 9.2 1.3 9.2 0.4 3.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) HRXXH PF13933.1 ETS61969.1 - 4.5e-89 298.1 0.9 4.5e-89 298.1 0.6 1.3 2 0 0 2 2 2 1 Putative peptidase family NAD_binding_4 PF07993.7 ETS61970.1 - 9.3e-63 211.4 0.1 6.5e-58 195.5 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein AMP-binding PF00501.23 ETS61970.1 - 5.6e-50 169.9 0.0 7.2e-39 133.3 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme adh_short PF00106.20 ETS61970.1 - 2.7e-35 121.7 5.5 1.5e-31 109.5 2.3 2.7 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 ETS61970.1 - 3.1e-22 79.1 0.1 6.5e-11 42.1 0.0 3.0 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS61970.1 - 8e-22 77.7 3.9 1.1e-17 64.2 2.0 2.6 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 ETS61970.1 - 2e-20 73.5 0.2 3.4e-19 69.5 0.2 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 ETS61970.1 - 8.6e-11 41.0 0.3 7.6e-06 24.8 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS61970.1 - 2.7e-09 37.2 3.6 0.0011 19.0 2.1 4.2 3 1 0 3 3 3 2 NADH(P)-binding PP-binding PF00550.20 ETS61970.1 - 2.3e-08 34.1 0.0 1.3e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS61970.1 - 1.6e-07 32.1 0.6 7e-07 30.1 0.1 2.6 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 ETS61970.1 - 8.5e-07 28.1 2.1 5.2e-05 22.2 0.2 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 ETS61970.1 - 0.0044 16.1 0.1 0.015 14.3 0.0 1.9 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 ETS61970.1 - 0.029 14.0 2.9 0.22 11.1 2.0 2.3 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 ETS61970.1 - 0.1 12.3 0.4 0.27 11.0 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 ETS61970.1 - 0.12 11.5 0.4 5.8 6.0 0.3 2.8 3 0 0 3 3 3 0 NmrA-like family NAD_binding_3 PF03447.11 ETS61970.1 - 0.47 10.8 6.8 6.4 7.2 0.0 3.5 3 1 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain TPR_16 PF13432.1 ETS61971.1 - 8.5e-08 32.6 6.7 0.28 11.9 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS61971.1 - 3.1e-07 30.4 9.4 0.0048 17.4 0.3 4.9 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS61971.1 - 4.5e-05 23.0 6.2 0.075 12.9 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS61971.1 - 0.0001 21.8 4.6 0.0034 16.9 2.6 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 ETS61971.1 - 0.0002 21.3 1.7 0.91 9.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS61971.1 - 0.011 16.0 6.9 0.22 11.9 1.2 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS61971.1 - 0.025 14.3 2.6 3.8 7.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETS61971.1 - 0.073 12.9 8.4 2.1 8.2 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS61971.1 - 0.075 13.1 3.8 0.22 11.6 2.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETS61971.1 - 6 7.5 5.9 32 5.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TIM PF00121.13 ETS61973.1 - 1.3e-58 197.9 0.0 1.6e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 ETS61974.1 - 6e-43 145.8 0.7 6.9e-43 145.6 0.5 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.1 ETS61974.1 - 0.032 14.0 0.8 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) DUF836 PF05768.9 ETS61975.1 - 6.3e-12 45.5 0.1 7.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.16 ETS61975.1 - 0.0039 16.8 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family GoLoco PF02188.12 ETS61975.1 - 0.091 12.1 0.2 1 8.8 0.0 2.1 2 0 0 2 2 2 0 GoLoco motif Surfac_D-trimer PF09006.6 ETS61976.1 - 1.4 8.7 3.9 4 7.2 0.6 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation TPR_11 PF13414.1 ETS61977.1 - 7e-14 51.2 12.0 1.1e-11 44.2 1.7 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETS61977.1 - 3e-06 26.5 7.0 0.094 12.3 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETS61977.1 - 6.1e-06 26.4 11.5 0.00011 22.4 1.4 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS61977.1 - 2.5e-05 23.8 8.3 0.039 13.8 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS61977.1 - 0.00071 20.1 16.6 0.014 16.0 1.2 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS61977.1 - 0.0015 18.9 13.6 0.036 14.7 0.3 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS61977.1 - 0.053 13.6 5.8 0.14 12.3 4.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETS61977.1 - 0.8 9.6 3.6 8.4 6.4 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS61977.1 - 1 9.3 10.7 0.31 11.0 2.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS61977.1 - 1.4 9.5 4.6 38 5.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUFA12 PF05071.11 ETS61978.1 - 1.1e-09 38.7 0.1 2.4e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF1421 PF07223.6 ETS61978.1 - 0.028 14.1 12.4 0.037 13.8 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Cse1 PF08506.5 ETS61979.1 - 1.8e-132 441.4 0.6 1.9e-130 434.7 0.4 2.3 2 0 0 2 2 2 2 Cse1 CAS_CSE1 PF03378.10 ETS61979.1 - 8.9e-117 390.0 0.1 1.9e-116 388.9 0.0 1.5 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 ETS61979.1 - 3.3e-11 42.9 3.4 1.1e-10 41.2 0.6 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 ETS61979.1 - 0.0042 17.0 6.4 0.0055 16.6 0.0 4.3 6 0 0 6 6 6 1 Exportin 1-like protein HEAT PF02985.17 ETS61979.1 - 0.019 15.0 0.3 25 5.3 0.0 4.5 3 0 0 3 3 3 0 HEAT repeat Rad51 PF08423.6 ETS61980.1 - 6e-10 38.4 0.3 5.9e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 ETS61980.1 - 3.2e-09 36.4 0.3 7.8e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 ETS61980.1 - 0.00024 20.2 0.5 0.006 15.6 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 ETS61980.1 - 0.035 13.2 0.3 0.079 12.0 0.0 1.7 2 0 0 2 2 2 0 KaiC Amino_oxidase PF01593.19 ETS61981.1 - 1.2e-11 44.3 0.0 1.2e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS61981.1 - 7.3e-10 38.7 0.1 1.5e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS61981.1 - 1.9e-05 24.8 0.1 4.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS61981.1 - 0.025 14.3 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS61981.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 ETS61981.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HtaA PF04213.8 ETS61981.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Htaa HI0933_like PF03486.9 ETS61981.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Hexokinase_2 PF03727.11 ETS61982.1 - 2.4e-77 259.4 0.0 3.5e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 ETS61982.1 - 3.9e-64 215.7 0.0 6.5e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase YjgF_endoribonc PF14588.1 ETS61982.1 - 0.089 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Aldo_ket_red PF00248.16 ETS61983.1 - 4.1e-48 163.6 0.0 5.1e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cupin_8 PF13621.1 ETS61985.1 - 5.2e-29 101.4 0.0 8.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETS61985.1 - 6.3e-05 22.3 0.2 0.00038 19.8 0.1 1.9 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 ETS61985.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.7 1 1 0 1 1 1 0 JmjC domain, hydroxylase AA_permease PF00324.16 ETS61986.1 - 2.1e-129 431.9 38.1 2.6e-129 431.6 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS61986.1 - 2e-36 125.4 41.2 2.5e-36 125.1 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease G-patch_2 PF12656.2 ETS61987.1 - 1e-25 89.3 4.2 1.2e-25 89.1 0.4 3.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 ETS61987.1 - 2.8e-05 23.7 7.8 6.3e-05 22.6 5.4 1.5 1 0 0 1 1 1 1 G-patch domain DUF747 PF05346.6 ETS61989.1 - 1.1e-122 409.2 3.1 1.4e-122 408.9 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family TypeIII_RM_meth PF12564.3 ETS61989.1 - 0.063 13.2 1.6 0.17 11.9 1.1 1.8 1 1 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit N2227 PF07942.7 ETS61990.1 - 1e-94 316.5 0.0 1.2e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Sod_Fe_C PF02777.13 ETS61991.1 - 1.2e-34 118.3 0.1 2.4e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETS61991.1 - 6.8e-32 109.5 5.5 7e-32 109.5 2.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 ETS61991.1 - 0.06 12.6 0.0 1.1 8.4 0.0 2.2 1 1 1 2 2 2 0 AsmA-like C-terminal region HAD PF12710.2 ETS61993.1 - 8.7e-15 55.3 0.0 1.1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 ETS61993.1 - 1.9e-09 37.2 0.0 3.9e-09 36.1 0.0 1.5 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 ETS61993.1 - 2.1e-05 24.7 0.0 9.5e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 ETS61993.1 - 0.00018 20.7 0.2 0.0011 18.1 0.1 1.9 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 ETS61993.1 - 0.085 13.2 1.1 0.51 10.7 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.7 ETS61993.1 - 0.093 12.9 0.1 0.62 10.2 0.0 2.4 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding RRM_1 PF00076.17 ETS61994.1 - 2.1e-57 190.6 0.0 7.6e-19 67.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS61994.1 - 1.3e-43 146.8 0.0 3.7e-15 55.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS61994.1 - 2.4e-25 88.1 0.0 6.6e-11 41.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS61994.1 - 4.3e-05 23.2 0.0 1.6 8.5 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 ETS61994.1 - 0.00012 21.7 0.0 0.96 9.2 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 ETS61994.1 - 0.011 15.1 0.0 13 5.0 0.0 3.2 3 0 0 3 3 3 0 ATP-grasp domain Metallophos PF00149.23 ETS61995.1 - 2.5e-42 144.5 0.3 3.5e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 ETS61996.1 - 1.5e-48 161.0 29.8 1.7e-11 43.5 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 ETS61996.1 - 2.9e-28 98.7 0.0 5.8e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 ETS61996.1 - 0.11 12.2 0.0 0.83 9.3 0.0 2.3 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETS61996.1 - 0.76 7.8 4.0 16 3.4 0.0 3.6 2 1 2 5 5 5 0 Nucleoporin Nup120/160 WES_acyltransf PF03007.11 ETS61997.1 - 2.7e-15 56.6 0.0 7e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain BRCA2 PF00634.13 ETS61999.1 - 0.23 10.8 0.8 9.3 5.6 0.0 2.6 2 0 0 2 2 2 0 BRCA2 repeat ATP-synt_E PF05680.7 ETS62000.1 - 2.5e-25 88.2 0.3 2.6e-25 88.1 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain ABC_trans_N PF14510.1 ETS62000.1 - 0.085 12.9 0.1 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal OEP PF02321.13 ETS62000.1 - 0.23 11.0 1.9 0.3 10.6 1.3 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein NAC PF01849.13 ETS62001.1 - 2.6e-20 71.6 0.0 4.2e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 NAC domain DMRL_synthase PF00885.14 ETS62002.1 - 7e-40 136.0 0.1 1.3e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase GST_C PF00043.20 ETS62002.1 - 1.4e-11 44.2 0.0 3.4e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS62002.1 - 3.2e-07 30.4 0.0 6.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS62002.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS62002.1 - 1.1e-05 25.7 0.0 2.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS62002.1 - 5.3e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ECH PF00378.15 ETS62004.1 - 4.7e-22 78.2 2.6 1.2e-12 47.5 0.1 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 ETS62004.1 - 9.4e-16 58.0 0.0 3.3e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Chromadorea_ALT PF05535.7 ETS62005.1 - 0.077 13.0 0.3 0.37 10.8 0.5 1.8 2 0 0 2 2 2 0 Chromadorea ALT protein Zn_clus PF00172.13 ETS62005.1 - 2.8 7.9 7.8 6.1 6.8 0.6 2.1 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3435 PF11917.3 ETS62007.1 - 0.0049 15.6 0.0 0.15 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) Clp1 PF06807.9 ETS62008.1 - 2e-20 73.3 0.0 1.3e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 ETS62008.1 - 0.014 15.1 0.0 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 ETS62008.1 - 0.016 15.1 0.0 7.9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 ETS62008.1 - 0.031 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETS62008.1 - 0.21 11.0 0.0 0.93 8.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 ETS62008.1 - 0.25 11.1 0.0 7.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 ETS62008.1 - 0.29 11.6 0.0 0.57 10.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AMP-binding PF00501.23 ETS62009.1 - 7.7e-95 317.7 0.1 9.5e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS62009.1 - 8.8e-25 87.4 1.1 1.1e-22 80.7 0.1 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.21 ETS62010.1 - 7.2e-28 96.7 0.0 5.1e-26 90.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS62010.1 - 8.1e-13 49.3 0.1 3.5e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS62010.1 - 6.4e-12 45.1 0.3 1.6e-11 43.9 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CPSase_L_chain PF00289.17 ETS62010.1 - 0.00054 20.0 0.8 0.0071 16.4 0.1 2.6 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Peripla_BP_6 PF13458.1 ETS62010.1 - 0.0072 15.7 0.2 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein adh_short PF00106.20 ETS62010.1 - 0.014 15.3 0.4 0.028 14.3 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase IF4E PF01652.13 ETS62011.1 - 4.5e-45 153.1 0.0 6.2e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E tRNA_U5-meth_tr PF05958.6 ETS62014.1 - 5.8e-24 84.4 0.0 2e-22 79.4 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 ETS62014.1 - 1e-11 44.6 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 ETS62014.1 - 3.3e-06 26.7 0.0 6.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 ETS62014.1 - 5e-06 27.0 0.0 1.7e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS62014.1 - 4.1e-05 23.6 0.7 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 ETS62014.1 - 5e-05 22.7 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 ETS62014.1 - 0.0005 19.1 0.0 0.00091 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 ETS62014.1 - 0.00063 20.1 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS62014.1 - 0.00099 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 ETS62014.1 - 0.0017 17.9 0.1 0.0037 16.8 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Ubie_methyltran PF01209.13 ETS62014.1 - 0.061 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPMT PF05724.6 ETS62014.1 - 0.063 12.7 0.0 0.18 11.1 0.0 1.8 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.1 ETS62014.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SKN1 PF03935.10 ETS62016.1 - 1.2e-187 624.1 1.6 1.4e-187 623.8 1.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 ETS62016.1 - 4.2e-06 26.1 3.9 0.0053 16.0 0.1 2.9 3 0 0 3 3 3 2 Glycosyl hydrolases family 16 Zn_clus PF00172.13 ETS62017.1 - 1.4e-08 34.5 11.9 2.3e-08 33.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Diphthamide_syn PF01866.12 ETS62018.1 - 1.3e-84 284.0 0.0 3.5e-30 105.3 0.1 4.1 4 0 0 4 4 4 4 Putative diphthamide synthesis protein WD40 PF00400.27 ETS62019.1 - 4.6e-08 32.6 10.6 0.1 12.4 0.1 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 ETS62019.1 - 9.4e-05 22.5 2.9 13 6.2 0.0 4.5 4 0 0 4 4 4 3 PQQ-like domain PQQ_2 PF13360.1 ETS62019.1 - 9.8e-05 21.9 0.2 0.022 14.2 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain DUF4013 PF13197.1 ETS62020.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF2370 PF10176.4 ETS62021.1 - 7e-77 257.9 2.4 7.2e-77 257.8 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2370) ABC_tran PF00005.22 ETS62022.1 - 2.7e-37 128.1 0.0 1.4e-21 77.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS62022.1 - 1.9e-36 125.8 22.3 3.2e-21 75.9 7.3 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS62022.1 - 8.8e-11 41.4 0.0 0.00051 19.3 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS62022.1 - 9.3e-06 25.0 1.3 0.0035 16.8 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 ETS62022.1 - 1.3e-05 25.3 0.7 0.018 15.0 0.0 3.1 3 1 1 4 4 3 1 AAA domain T2SE PF00437.15 ETS62022.1 - 0.00014 20.9 0.1 0.024 13.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 ETS62022.1 - 0.00034 20.6 4.2 0.014 15.3 0.1 3.2 3 0 0 3 3 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS62022.1 - 0.002 17.6 0.3 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 ETS62022.1 - 0.0022 18.4 0.3 0.16 12.4 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 ETS62022.1 - 0.0071 16.1 0.2 0.0071 16.1 0.1 1.8 2 0 0 2 2 1 1 Domain of unknown function DUF87 MobB PF03205.9 ETS62022.1 - 0.0075 15.9 0.7 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 ETS62022.1 - 0.0086 15.9 0.4 1.4 8.8 0.1 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 ETS62022.1 - 0.011 16.5 0.7 0.068 13.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 ETS62022.1 - 0.012 14.3 0.1 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein TrwB_AAD_bind PF10412.4 ETS62022.1 - 0.02 13.5 0.4 0.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 ETS62022.1 - 0.02 15.0 2.8 7 6.7 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 ETS62022.1 - 0.026 13.9 3.2 0.78 9.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 ETS62022.1 - 0.029 13.8 1.4 1.1 8.5 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 ETS62022.1 - 0.03 13.7 3.1 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 ETS62022.1 - 0.038 14.3 0.9 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 ETS62022.1 - 0.041 13.3 0.2 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 ETS62022.1 - 0.043 13.6 0.3 2.9 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 ETS62022.1 - 0.05 12.7 0.3 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS62022.1 - 0.054 13.4 1.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 ETS62022.1 - 0.064 12.9 0.1 8.5 6.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 ETS62022.1 - 0.12 11.9 0.6 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 ETS62022.1 - 0.22 10.8 1.6 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.18 ETS62022.1 - 0.27 11.0 2.4 12 5.6 0.2 2.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 ETS62022.1 - 0.35 11.1 2.1 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Aa_trans PF01490.13 ETS62024.1 - 1.7e-31 109.0 29.3 2.4e-31 108.6 20.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MMPL PF03176.10 ETS62024.1 - 0.033 12.8 6.0 0.096 11.3 2.5 2.2 2 0 0 2 2 2 0 MMPL family YadA_stalk PF05662.9 ETS62024.1 - 0.073 12.8 0.2 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin DUF2416 PF10315.4 ETS62026.1 - 1.3e-10 41.5 0.5 2.2e-10 40.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2416) Chitin_synth_2 PF03142.10 ETS62027.1 - 6.8e-229 760.6 0.1 9.8e-229 760.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.23 ETS62027.1 - 5.2e-25 87.0 0.0 1.4e-16 60.0 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 ETS62027.1 - 4.7e-18 64.7 0.0 4.2e-15 55.2 0.1 2.5 2 0 0 2 2 2 2 DEK C terminal domain Glyco_trans_2_3 PF13632.1 ETS62027.1 - 8.5e-16 58.2 2.2 8.5e-16 58.2 1.5 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS62027.1 - 4.4e-15 56.1 0.2 6.2e-12 45.8 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS62027.1 - 7.8e-07 28.9 0.1 0.0014 18.3 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ETS62027.1 - 1.9e-05 24.0 0.0 6.3e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1643 PF07799.7 ETS62027.1 - 0.0077 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1643) DUF1622 PF07784.6 ETS62027.1 - 0.026 14.1 2.2 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) Jiv90 PF14901.1 ETS62027.1 - 0.036 14.0 0.2 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone HSF_DNA-bind PF00447.12 ETS62028.1 - 1.1e-28 99.3 0.0 1.8e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Tmemb_cc2 PF10267.4 ETS62028.1 - 1.2 7.6 8.5 0.16 10.5 0.2 2.6 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein AA_permease_2 PF13520.1 ETS62029.1 - 1.4e-61 208.3 44.6 1.8e-61 207.9 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS62029.1 - 6.8e-22 77.4 40.0 9e-22 77.0 27.8 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 ETS62029.1 - 0.22 11.3 0.0 0.22 11.3 0.0 4.0 4 0 0 4 4 4 0 Gram positive anchor TFIIF_beta PF02270.10 ETS62030.1 - 2.7e-56 191.3 0.0 3.9e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF3245 PF11595.3 ETS62030.1 - 2.3 8.5 13.0 2.2 8.5 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Ribonuclease_3 PF00636.21 ETS62031.1 - 5e-09 36.6 0.0 9.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 ETS62031.1 - 6e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 ETS62031.1 - 1.8e-06 27.9 0.0 0.025 14.5 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease-III-like HTH_Tnp_1 PF01527.15 ETS62031.1 - 0.071 13.0 0.1 14 5.7 0.0 2.8 2 0 0 2 2 2 0 Transposase WD40 PF00400.27 ETS62032.1 - 9.6e-52 171.1 7.7 7.7e-12 44.6 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat DUF3312 PF11768.3 ETS62032.1 - 0.011 13.9 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 ETS62032.1 - 0.017 13.9 0.1 3.8 6.1 0.0 3.7 2 1 1 3 3 3 0 Nup133 N terminal like VID27 PF08553.5 ETS62032.1 - 0.072 11.3 0.0 0.24 9.5 0.0 1.7 2 0 0 2 2 2 0 VID27 cytoplasmic protein Nup160 PF11715.3 ETS62032.1 - 0.084 11.0 6.6 1.7 6.7 0.2 4.2 3 2 1 4 4 4 0 Nucleoporin Nup120/160 DUF4078 PF13300.1 ETS62033.1 - 1.7e-11 44.0 4.3 1.7e-11 44.0 3.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) HTH_9 PF08221.6 ETS62034.1 - 1.2e-16 60.3 0.9 5.8e-08 32.5 0.0 5.4 5 0 0 5 5 5 4 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 ETS62034.1 - 9.9e-16 58.0 0.2 1.5e-14 54.1 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 ETS62034.1 - 1.3e-05 24.6 0.3 6.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit TruB_N PF01509.13 ETS62035.1 - 2.7e-38 131.4 0.0 2.1e-37 128.5 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Abhydrolase_6 PF12697.2 ETS62036.1 - 8.7e-19 68.3 0.0 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DcpS_C PF11969.3 ETS62036.1 - 1.4e-18 67.1 0.0 2.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Abhydrolase_5 PF12695.2 ETS62036.1 - 2.9e-15 56.2 0.0 6.1e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS62036.1 - 1.8e-07 30.9 0.0 5.5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 ETS62036.1 - 3e-06 26.9 0.4 0.00061 19.4 0.0 3.0 4 0 0 4 4 4 1 alpha/beta hydrolase fold HIT PF01230.18 ETS62036.1 - 2.9e-05 24.5 3.1 0.00039 20.9 2.1 2.2 1 1 0 1 1 1 1 HIT domain Abhydrolase_3 PF07859.8 ETS62036.1 - 4.7e-05 23.0 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 ETS62036.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 ETS62036.1 - 0.038 13.2 0.1 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 ETS62036.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Methyltransf_23 PF13489.1 ETS62037.1 - 2.7e-22 79.2 0.0 3.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS62037.1 - 9.5e-19 67.6 0.0 1.8e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS62037.1 - 1.1e-14 54.2 0.0 3.1e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS62037.1 - 8.2e-13 48.6 0.0 2.4e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS62037.1 - 8e-12 45.7 0.0 1.8e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS62037.1 - 1.5e-07 31.6 0.1 3.9e-07 30.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS62037.1 - 2e-07 31.0 0.5 6.8e-07 29.3 0.1 2.1 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 ETS62037.1 - 6.9e-05 21.6 0.0 0.00014 20.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 ETS62037.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 ETS62037.1 - 0.00018 20.6 0.0 0.00058 19.0 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 ETS62037.1 - 0.0011 18.3 0.0 0.0047 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 ETS62037.1 - 0.0015 18.0 0.0 0.0041 16.5 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 ETS62037.1 - 0.0044 16.1 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 ETS62037.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mpp10 PF04006.7 ETS62038.1 - 2.5e-88 296.9 123.8 1.4e-82 278.0 24.6 3.3 1 1 1 3 3 3 3 Mpp10 protein DENN PF02141.16 ETS62039.1 - 5.6e-20 71.8 0.0 9.2e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain Methyltransf_16 PF10294.4 ETS62039.1 - 7.8e-12 44.9 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETS62039.1 - 0.001 19.6 2.0 0.0044 17.5 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain UPF0242 PF06785.6 ETS62039.1 - 0.0067 15.1 4.7 0.011 14.4 3.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) FlxA PF14282.1 ETS62039.1 - 0.015 15.2 14.2 0.36 10.7 4.3 2.9 2 0 0 2 2 2 0 FlxA-like protein tRNA-synt_1c PF00749.16 ETS62039.1 - 0.047 12.3 1.8 0.1 11.2 0.7 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Methyltransf_23 PF13489.1 ETS62039.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain IFT57 PF10498.4 ETS62039.1 - 0.39 9.3 12.3 0.83 8.3 3.8 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Syntaxin PF00804.20 ETS62039.1 - 2 8.5 16.0 0.87 9.7 0.5 2.9 3 0 0 3 3 2 0 Syntaxin TMF_TATA_bd PF12325.3 ETS62039.1 - 3.7 7.2 22.4 0.021 14.5 5.7 3.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 ETS62039.1 - 5.8 4.4 23.7 0.24 9.0 11.2 1.9 2 0 0 2 2 2 0 Myosin tail Baculo_PEP_C PF04513.7 ETS62039.1 - 8.8 6.1 7.3 3.3 7.5 0.3 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugar_tr PF00083.19 ETS62040.1 - 3e-86 289.8 24.7 3.7e-86 289.5 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS62040.1 - 8.6e-13 47.7 44.7 2.3e-10 39.7 13.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ArfGap PF01412.13 ETS62041.1 - 3.3e-41 139.7 0.1 5.9e-41 138.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SARA PF11409.3 ETS62041.1 - 0.044 13.6 0.8 0.044 13.6 0.6 3.6 4 0 0 4 4 4 0 Smad anchor for receptor activation (SARA) SUI1 PF01253.17 ETS62044.1 - 2e-12 46.7 0.0 4.6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 ETS62044.1 - 0.0012 18.7 0.3 0.0017 18.1 0.2 1.2 1 0 0 1 1 1 1 Transposon-encoded protein TnpV SPATIAL PF15256.1 ETS62044.1 - 0.05 13.6 0.3 0.098 12.7 0.2 1.5 1 0 0 1 1 1 0 SPATIAL DUF1771 PF08590.5 ETS62045.1 - 2.5e-24 85.0 5.8 2.5e-23 81.8 4.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 ETS62045.1 - 4.5e-15 55.6 0.3 1e-14 54.4 0.2 1.7 1 0 0 1 1 1 1 Smr domain HJURP_C PF12347.3 ETS62045.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Peripla_BP_2 PF01497.13 ETS62045.1 - 0.055 12.5 0.2 0.087 11.9 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Mon1 PF03164.9 ETS62046.1 - 1.4e-75 254.4 0.0 8.1e-51 172.9 0.0 3.2 3 0 0 3 3 3 3 Trafficking protein Mon1 DUF77 PF01910.12 ETS62047.1 - 1.8e-25 88.4 0.0 2.1e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 ETS62047.1 - 0.0048 17.0 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family FTCD PF02971.9 ETS62047.1 - 0.12 12.0 0.1 1.1 8.8 0.0 2.0 1 1 1 2 2 2 0 Formiminotransferase domain MutS_V PF00488.16 ETS62048.1 - 7.7e-93 310.2 0.0 1.2e-92 309.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS62048.1 - 2.1e-35 122.3 0.9 2.1e-35 122.3 0.6 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 ETS62048.1 - 2.2e-17 63.4 0.0 9.9e-17 61.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 ETS62048.1 - 1.3e-14 54.1 0.4 1.3e-14 54.1 0.3 2.3 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 ETS62048.1 - 2.2e-12 46.9 0.0 4.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain I zf-ZPR1 PF03367.8 ETS62048.1 - 0.019 14.1 0.1 0.17 11.0 0.0 2.6 4 0 0 4 4 4 0 ZPR1 zinc-finger domain Ribonuclease_T2 PF00445.13 ETS62049.1 - 5.4e-23 81.5 0.0 1.4e-22 80.2 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease T2 family TGS PF02824.16 ETS62050.1 - 3.6e-21 74.7 0.0 6.5e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 ETS62050.1 - 7.8e-18 64.5 0.1 2e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS62050.1 - 2.6e-09 36.5 0.1 8.9e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETS62050.1 - 0.0097 15.7 0.4 0.38 10.5 0.0 2.5 1 1 0 2 2 2 1 Dynamin family ArgK PF03308.11 ETS62050.1 - 0.04 12.7 3.4 0.091 11.5 0.4 2.4 2 1 1 3 3 3 0 ArgK protein FAD_binding_3 PF01494.14 ETS62051.1 - 2.2e-26 92.7 0.2 4e-26 91.9 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS62051.1 - 7e-14 51.4 0.8 2.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS62051.1 - 6.9e-09 35.9 0.1 0.00012 22.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS62051.1 - 2.8e-06 27.2 0.2 7.5e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS62051.1 - 1.6e-05 23.7 0.7 0.0034 16.0 0.0 2.8 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS62051.1 - 2e-05 24.5 0.1 0.00015 21.6 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS62051.1 - 9.2e-05 22.5 0.1 0.00086 19.4 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS62051.1 - 0.0005 18.6 0.2 0.21 10.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 ETS62051.1 - 0.0023 16.8 1.0 0.046 12.5 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 ETS62051.1 - 0.0055 15.6 0.3 0.015 14.1 0.2 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 ETS62051.1 - 0.0084 15.5 0.2 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 ETS62051.1 - 0.013 15.0 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 ETS62051.1 - 0.034 13.8 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 ETS62051.1 - 0.063 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 ETS62051.1 - 0.065 12.1 0.6 1.4 7.7 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein SE PF08491.5 ETS62051.1 - 0.096 11.4 0.0 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Cyt-b5 PF00173.23 ETS62052.1 - 6.8e-10 38.6 0.1 8.9e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PNPOx_C PF10590.4 ETS62053.1 - 1.8e-22 78.5 0.4 3.4e-22 77.6 0.2 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 ETS62053.1 - 5.9e-19 67.8 0.0 1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 ETS62053.1 - 0.0022 18.3 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Shisa PF13908.1 ETS62054.1 - 0.23 11.6 0.7 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 ETS62054.1 - 0.78 8.9 8.3 0.52 9.5 4.4 1.6 1 1 0 1 1 1 0 Tetraspanin family Amidohydro_3 PF07969.6 ETS62055.1 - 5e-55 187.3 0.2 5.8e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS62055.1 - 2.7e-10 39.9 0.1 1.5e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS62055.1 - 2.9e-08 33.7 0.0 0.00034 20.3 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 ETS62055.1 - 1.2e-07 32.0 1.1 0.00038 20.5 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase EAP30 PF04157.11 ETS62058.1 - 9.2e-52 175.4 0.0 1.3e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 ETS62058.1 - 1.7e-29 101.4 0.0 3e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 ETS62058.1 - 0.0023 17.0 22.5 0.0032 16.5 1.0 3.4 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 ETS62058.1 - 0.0078 16.0 11.4 0.62 9.9 0.3 3.3 3 0 0 3 3 3 2 Double zinc ribbon DUF1024 PF06260.7 ETS62058.1 - 0.014 15.4 0.2 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Prim_Zn_Ribbon PF08273.7 ETS62058.1 - 2.5 8.2 5.5 0.87 9.7 0.0 2.9 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase CLU PF13236.1 ETS62059.1 - 1.6e-74 250.1 0.0 2.4e-74 249.5 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 ETS62059.1 - 6.5e-43 146.5 0.0 1.5e-42 145.4 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 ETS62059.1 - 7.5e-19 67.4 3.6 1.8e-09 37.3 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS62059.1 - 2.7e-10 39.8 9.1 0.001 18.9 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.1 ETS62059.1 - 8.9e-05 22.5 0.1 0.00052 20.1 0.1 2.2 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term HMG-CoA_red PF00368.13 ETS62060.1 - 7.5e-162 538.2 5.2 1e-161 537.7 3.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 ETS62060.1 - 9.6e-17 60.8 2.6 4.9e-08 32.5 0.1 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 ETS62060.1 - 3.4e-08 31.9 0.4 0.0015 16.5 0.0 2.3 2 0 0 2 2 2 2 Patched family HPIH PF13323.1 ETS62060.1 - 0.0056 16.3 0.4 0.017 14.8 0.3 1.8 1 0 0 1 1 1 1 N-terminal domain with HPIH motif PITH PF06201.8 ETS62061.1 - 4.4e-37 127.1 0.0 5.4e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 PITH domain C2 PF00168.25 ETS62062.1 - 6.1e-22 77.2 0.0 3e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Ribosomal_L38e PF01781.13 ETS62063.1 - 2.8e-32 110.2 1.4 4.4e-32 109.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L38e protein family E6 PF00518.12 ETS62063.1 - 0.073 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Early Protein (E6) Ribosomal_S11 PF00411.14 ETS62064.1 - 7.9e-07 29.2 0.1 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 EVE PF01878.13 ETS62065.1 - 1e-44 152.0 0.0 1.7e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 EVE domain MCLC PF05934.6 ETS62065.1 - 0.08 11.2 0.9 0.11 10.7 0.6 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Mpv17_PMP22 PF04117.7 ETS62066.1 - 9.6e-23 79.6 0.2 1.5e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family HIG_1_N PF04588.8 ETS62066.1 - 1.7 8.4 7.1 7.9 6.3 0.4 2.9 2 1 1 3 3 3 0 Hypoxia induced protein conserved region BCIP PF13862.1 ETS62068.1 - 2.5e-55 187.0 0.0 3.1e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Aldo_ket_red PF00248.16 ETS62069.1 - 8.6e-72 241.3 0.0 1.1e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 ETS62070.1 - 1e-53 180.8 1.0 1e-53 180.8 0.7 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain SCP2 PF02036.12 ETS62070.1 - 8.3e-24 83.8 2.0 1.9e-23 82.6 1.4 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 ETS62070.1 - 0.00051 20.0 0.6 0.00094 19.1 0.4 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal MBOAT PF03062.14 ETS62071.1 - 1.2e-46 159.3 18.3 1.2e-46 159.3 12.7 1.9 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Claudin_2 PF13903.1 ETS62072.1 - 0.0082 15.8 3.1 0.045 13.4 0.3 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF456 PF04306.8 ETS62072.1 - 1.2 9.1 9.3 1.5 8.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF456) CopD PF05425.8 ETS62072.1 - 1.5 9.0 9.7 2.6 8.3 4.3 2.4 2 1 0 2 2 2 0 Copper resistance protein D DUF1056 PF06341.6 ETS62072.1 - 7.6 6.6 9.5 0.3 11.1 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Bot1p PF12298.3 ETS62074.1 - 2.3e-32 112.3 0.1 3.7e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 ETS62074.1 - 0.00024 21.1 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF106 PF01956.11 ETS62075.1 - 3.5e-59 199.1 0.2 4.8e-59 198.6 0.1 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 NPR3 PF03666.8 ETS62076.1 - 2.9e-114 382.1 12.9 1.9e-113 379.3 0.0 3.2 3 1 1 4 4 4 1 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S24 PF00717.18 ETS62076.1 - 0.0029 17.2 0.0 0.044 13.4 0.0 2.4 2 0 0 2 2 2 1 Peptidase S24-like NPR2 PF06218.6 ETS62076.1 - 0.067 11.8 0.1 5.5 5.5 0.0 2.6 3 0 0 3 3 3 0 Nitrogen permease regulator 2 PEMT PF04191.8 ETS62077.1 - 3.2e-53 178.2 10.3 9.5e-32 109.2 1.3 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase RRM_1 PF00076.17 ETS62078.1 - 1.4e-22 79.1 0.0 4.6e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS62078.1 - 3e-14 52.7 0.0 1.4e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS62078.1 - 0.003 17.3 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAGE PF01454.14 ETS62079.1 - 4.9e-33 114.1 0.0 3.7e-29 101.4 0.0 2.7 2 1 0 2 2 2 2 MAGE family LRR_4 PF12799.2 ETS62080.1 - 5.7e-24 83.2 17.1 1.3e-06 27.8 3.3 5.6 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS62080.1 - 5.2e-17 61.3 20.3 2e-07 30.6 2.5 5.4 4 1 1 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 ETS62080.1 - 9.7e-13 46.2 16.2 0.21 11.7 0.0 8.2 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.1 ETS62080.1 - 1.3e-09 37.1 16.0 2.4 8.5 0.0 7.6 7 0 0 7 7 7 4 Leucine Rich repeat LRR_7 PF13504.1 ETS62080.1 - 2.6e-09 35.7 18.9 0.48 10.8 0.1 8.3 8 0 0 8 8 8 3 Leucine rich repeat zf-CCCH PF00642.19 ETS62080.1 - 9.7e-05 21.9 6.5 0.0014 18.2 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_3 PF07725.7 ETS62080.1 - 0.02 14.6 0.5 0.02 14.6 0.3 2.4 3 0 0 3 3 3 0 Leucine Rich Repeat adh_short PF00106.20 ETS62081.1 - 1.5e-18 67.3 0.2 1.5e-18 67.3 0.1 2.5 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 ETS62081.1 - 1.7e-10 40.8 0.1 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS62081.1 - 1.9e-05 24.5 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2018 PF09442.5 ETS62081.1 - 0.0007 20.1 0.3 0.0015 19.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2018) NAD_binding_10 PF13460.1 ETS62081.1 - 0.0064 16.5 0.6 1.1 9.1 0.4 2.7 1 1 0 1 1 1 1 NADH(P)-binding Virulence_fact PF13769.1 ETS62081.1 - 0.093 12.6 0.4 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Virulence factor MT-A70 PF05063.9 ETS62082.1 - 3e-49 166.9 0.0 1.3e-32 112.8 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Methyltransf_26 PF13659.1 ETS62082.1 - 0.0019 18.2 0.0 0.0052 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 ETS62083.1 - 2.7e-46 153.8 36.7 7.5e-08 31.9 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 ETS62083.1 - 1.6e-09 37.3 0.4 3.6e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS62083.1 - 0.00034 20.1 0.2 0.00089 18.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 ETS62083.1 - 0.0077 15.0 0.2 0.69 8.5 0.0 3.0 2 2 1 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.1 ETS62083.1 - 0.015 14.7 0.6 0.13 11.7 0.1 2.3 2 0 0 2 2 2 0 PQQ-like domain Nup160 PF11715.3 ETS62083.1 - 0.22 9.6 5.9 0.46 8.5 0.1 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 HD PF01966.17 ETS62084.1 - 0.083 12.9 0.1 0.21 11.5 0.1 1.8 1 1 0 1 1 1 0 HD domain ADH_zinc_N PF00107.21 ETS62085.1 - 1.8e-11 43.7 0.2 2.7e-11 43.1 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 ETS62085.1 - 0.00042 19.7 0.1 0.00064 19.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_2 PF08028.6 ETS62087.1 - 1.7e-16 60.7 2.5 2.9e-16 59.9 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS62087.1 - 4.4e-08 33.6 0.5 3e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 ETS62087.1 - 0.017 15.1 1.8 0.082 13.0 1.3 2.1 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-C2H2_2 PF12756.2 ETS62088.1 - 0.027 14.5 0.1 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PI-PLC-X PF00388.14 ETS62089.1 - 1.3e-56 190.1 0.0 2.3e-56 189.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 ETS62089.1 - 4.5e-39 133.0 0.0 9.1e-39 132.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.1 ETS62089.1 - 7.2e-07 29.2 0.6 2.3e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_like PF09279.6 ETS62089.1 - 3.1e-06 27.1 0.0 1.3e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 ETS62089.1 - 8.2e-05 21.6 0.0 0.3 10.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETS62089.1 - 0.00033 20.2 0.2 0.15 12.0 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.1 ETS62089.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 EF hand C2 PF00168.25 ETS62089.1 - 0.014 15.2 0.1 2.9 7.8 0.0 3.0 3 0 0 3 3 3 0 C2 domain EF-hand_8 PF13833.1 ETS62089.1 - 0.014 14.9 0.2 3 7.5 0.0 2.9 2 1 2 4 4 4 0 EF-hand domain pair CreD PF06123.7 ETS62089.1 - 0.085 11.3 0.5 0.13 10.7 0.3 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD DPBB_1 PF03330.13 ETS62090.1 - 4.3e-07 29.8 0.2 1.9e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel LZ_Tnp_IS66 PF13007.2 ETS62090.1 - 0.073 13.7 1.3 0.13 12.9 0.9 1.4 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain SelP_N PF04592.9 ETS62090.1 - 0.2 11.0 2.2 0.3 10.4 1.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ILVD_EDD PF00920.16 ETS62091.1 - 3.7e-180 599.7 0.6 1.1e-158 528.9 0.6 2.0 1 1 1 2 2 2 2 Dehydratase family Methyltransf_16 PF10294.4 ETS62092.1 - 4.2e-06 26.3 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 ETS62092.1 - 0.00014 21.4 0.0 0.055 13.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 ETS62092.1 - 0.014 15.7 0.0 0.1 12.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain GST_C_2 PF13410.1 ETS62093.1 - 1.7e-13 50.2 0.0 4.7e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS62093.1 - 9.8e-08 32.1 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS62093.1 - 2.3e-05 24.2 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS62093.1 - 0.00098 19.5 0.2 0.0051 17.2 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS62093.1 - 0.0017 18.5 0.0 0.0043 17.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS62093.1 - 0.092 12.7 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ATXN-1_C PF12547.3 ETS62093.1 - 0.27 11.2 4.8 1.9 8.5 0.0 3.0 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator RRM_1 PF00076.17 ETS62094.1 - 1.3e-07 31.1 0.1 4.1e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS62094.1 - 2.2e-07 30.5 0.0 8.3e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS62094.1 - 0.00025 20.7 0.0 0.00059 19.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 ETS62094.1 - 0.00096 19.0 0.1 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 ETS62094.1 - 0.013 15.2 5.4 0.024 14.3 3.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_6 PF13516.1 ETS62095.1 - 2.3e-14 51.7 18.3 0.52 10.5 0.0 10.7 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.2 ETS62095.1 - 2.2e-09 36.7 23.4 4.9e-05 22.8 0.4 7.2 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) GAT PF03127.9 ETS62095.1 - 0.0023 17.8 0.0 0.0072 16.2 0.0 1.8 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.28 ETS62095.1 - 0.0041 16.9 18.1 4.5 7.6 0.0 8.5 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.1 ETS62095.1 - 0.079 12.7 19.8 0.043 13.5 0.9 5.7 5 3 2 7 7 7 0 Leucine rich repeat LRR_7 PF13504.1 ETS62095.1 - 2.4 8.7 22.1 54 4.6 0.1 9.2 11 0 0 11 11 11 0 Leucine rich repeat Pal1 PF08316.6 ETS62096.1 - 2.1e-13 50.9 0.7 2.1e-13 50.9 0.5 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein ATG22 PF11700.3 ETS62097.1 - 1.7e-128 429.1 17.2 1.9e-128 428.9 11.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 ETS62097.1 - 2e-11 43.1 28.0 8.5e-06 24.7 4.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4064 PF13273.1 ETS62097.1 - 1.9 8.6 13.0 1.6 8.9 2.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) LAMTOR PF15454.1 ETS62098.1 - 4e-07 30.2 0.2 2.8e-06 27.5 0.1 2.2 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator CAP PF00188.21 ETS62098.1 - 0.11 12.9 0.4 0.35 11.3 0.2 1.8 1 1 1 2 2 2 0 Cysteine-rich secretory protein family zf-RING_2 PF13639.1 ETS62099.1 - 1.3e-12 47.3 7.1 2.1e-12 46.6 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS62099.1 - 3.4e-09 36.5 2.8 8.9e-09 35.2 1.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS62099.1 - 3.2e-08 33.5 3.6 5.7e-08 32.7 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS62099.1 - 2.6e-07 30.1 4.7 4.9e-07 29.2 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS62099.1 - 6.5e-07 28.9 4.3 1.1e-06 28.2 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS62099.1 - 3.6e-05 23.3 5.1 0.0001 21.8 3.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS62099.1 - 0.00041 20.0 4.6 0.0013 18.4 3.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETS62099.1 - 0.0011 18.6 3.0 0.0021 17.8 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 ETS62099.1 - 0.0067 16.4 0.4 0.015 15.3 0.3 1.5 1 0 0 1 1 1 1 RING-like domain RINGv PF12906.2 ETS62099.1 - 0.044 13.8 4.1 0.11 12.5 2.9 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 ETS62099.1 - 0.064 12.7 3.6 0.12 11.8 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 ETS62099.1 - 0.076 12.9 4.8 0.53 10.2 3.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 ETS62099.1 - 0.12 12.3 0.4 0.12 12.3 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 ETS62099.1 - 0.15 11.6 5.1 0.69 9.5 3.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 ETS62099.1 - 0.7 9.4 2.9 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 ETS62099.1 - 1.3 8.6 7.0 0.36 10.3 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Acyl_transf_1 PF00698.16 ETS62100.1 - 1.1e-55 189.2 0.1 7.2e-55 186.5 0.0 2.4 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 ETS62100.1 - 7.1e-28 96.4 0.3 8.3e-27 93.0 0.0 2.5 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.21 ETS62100.1 - 4.1e-27 95.2 0.5 1e-26 94.0 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF1729 PF08354.5 ETS62100.1 - 7.3e-25 86.5 0.0 1.9e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) adh_short_C2 PF13561.1 ETS62100.1 - 1e-19 71.3 0.0 2.3e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 ETS62100.1 - 8.2e-16 57.9 0.8 8.2e-16 57.9 0.5 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 ETS62100.1 - 3e-12 46.3 0.0 1.9e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Thiolase_N PF00108.18 ETS62100.1 - 0.0015 17.5 0.0 0.0035 16.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Tenui_NS3 PF05310.7 ETS62100.1 - 1.7 8.5 0.0 3.5 7.4 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus movement protein Vps53_N PF04100.7 ETS62100.1 - 5 5.7 0.0 9.8 4.8 0.0 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal LETM1 PF07766.8 ETS62101.1 - 3.3e-23 82.0 0.1 7.8e-20 71.0 0.1 2.3 1 1 0 1 1 1 1 LETM1-like protein UQ_con PF00179.21 ETS62102.1 - 7e-36 122.7 0.0 1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Astro_capsid_p PF12226.3 ETS62102.1 - 0.065 12.4 0.5 0.098 11.8 0.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Bd3614_N PF14442.1 ETS62102.1 - 1.1 9.2 4.6 1.8 8.5 3.2 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal LSM PF01423.17 ETS62103.1 - 1e-14 53.7 0.9 1.5e-14 53.2 0.6 1.2 1 0 0 1 1 1 1 LSM domain NDK PF00334.14 ETS62104.1 - 1.3e-51 173.9 0.0 1.9e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Sin_N PF04801.8 ETS62105.1 - 1.4e-24 86.7 0.1 1.2e-23 83.6 0.0 2.0 2 0 0 2 2 2 1 Sin-like protein conserved region Pex24p PF06398.6 ETS62106.1 - 6.8e-26 90.9 5.6 1.1e-25 90.2 0.1 2.4 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Gtr1_RagA PF04670.7 ETS62107.1 - 1.1e-27 96.6 2.0 6.3e-15 54.9 1.3 4.0 3 1 0 3 3 3 3 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS62107.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase C1-set PF07654.10 ETS62107.1 - 0.097 12.6 0.1 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Arch_ATPase PF01637.13 ETS62107.1 - 0.098 12.3 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Arf PF00025.16 ETS62107.1 - 0.12 11.6 0.1 1.8 7.7 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 ETS62107.1 - 0.14 12.6 0.0 15 6.1 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 ETS62107.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNase_P_pop3 PF08228.6 ETS62108.1 - 6.4e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 RNase P subunit Pop3 Oxysterol_BP PF01237.13 ETS62109.1 - 5.8e-68 228.9 0.0 5.8e-48 163.1 0.0 3.1 2 1 1 3 3 3 3 Oxysterol-binding protein Ada3 PF10198.4 ETS62110.1 - 2.4e-38 130.8 0.1 7.2e-38 129.3 0.0 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 HEAT PF02985.17 ETS62111.1 - 4.1e-41 135.3 21.3 0.0014 18.4 0.0 13.6 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 ETS62111.1 - 7.2e-33 112.7 8.6 3.2e-09 36.9 0.0 6.7 2 1 5 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 ETS62111.1 - 2.6e-11 43.7 1.9 0.011 16.0 0.0 6.9 4 2 4 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETS62111.1 - 7.5e-09 35.8 16.2 0.49 10.9 0.0 8.5 7 2 1 8 8 8 3 HEAT-like repeat Adaptin_N PF01602.15 ETS62111.1 - 1.4e-06 26.9 6.9 0.086 11.1 0.0 4.8 3 1 1 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 ETS62111.1 - 0.00063 19.1 1.8 0.39 10.0 0.0 4.6 2 2 3 5 5 5 1 CLASP N terminal Arm PF00514.18 ETS62111.1 - 0.002 17.9 0.8 6.9 6.6 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 ETS62111.1 - 0.07 13.6 0.1 19 6.1 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF2435 PF10363.4 ETS62111.1 - 0.12 12.2 3.1 4.4 7.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) ACBP PF00887.14 ETS62112.1 - 2e-33 113.8 0.1 2.7e-33 113.4 0.1 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein SWIB PF02201.13 ETS62113.1 - 8.9e-17 60.5 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Memo PF01875.12 ETS62114.1 - 3.9e-75 252.2 0.0 6.6e-75 251.5 0.0 1.3 1 1 0 1 1 1 1 Memo-like protein Ribosomal_S3_C PF00189.15 ETS62115.1 - 1.9e-16 60.0 1.2 2.3e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 ETS62115.1 - 2.1e-13 49.6 0.0 3.7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 ETS62115.1 - 0.027 14.7 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 HABP4_PAI-RBP1 PF04774.10 ETS62116.1 - 5.9e-09 36.3 6.7 5.9e-09 36.3 4.7 3.0 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Arrestin_N PF00339.24 ETS62117.1 - 4.3e-05 23.3 0.0 0.00037 20.3 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 ETS62117.1 - 0.00049 20.2 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 ETS62117.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein CAF-1_p150 PF11600.3 ETS62117.1 - 6.7 6.0 48.1 0.56 9.5 29.0 2.3 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SSF PF00474.12 ETS62119.1 - 3.9e-12 45.5 18.4 1.1e-11 44.0 12.7 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family RPAP2_Rtr1 PF04181.8 ETS62120.1 - 1.7e-16 60.0 0.0 2.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DAP3 PF10236.4 ETS62120.1 - 0.0041 16.0 0.1 0.0063 15.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NUDIX PF00293.23 ETS62121.1 - 2.7e-12 46.5 0.0 6.6e-12 45.2 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain TIMELESS PF04821.9 ETS62122.1 - 2.4e-32 112.2 7.1 4.2e-31 108.1 2.0 3.2 2 1 0 2 2 2 1 Timeless protein DCP1 PF06058.8 ETS62123.1 - 9.4e-25 87.0 0.0 1.7e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DUF3987 PF13148.1 ETS62123.1 - 0.15 10.5 9.8 0.2 10.1 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NARP1 PF12569.3 ETS62123.1 - 0.3 9.7 15.2 0.42 9.2 10.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BLVR PF06375.6 ETS62123.1 - 0.86 9.4 17.5 1.2 8.9 11.7 1.5 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) FancD2 PF14631.1 ETS62123.1 - 1.6 5.7 10.6 2.2 5.2 7.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SR-25 PF10500.4 ETS62123.1 - 2.2 7.7 23.5 0.36 10.2 13.7 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rtf2 PF04641.7 ETS62123.1 - 2.2 7.4 14.0 3.6 6.7 9.7 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Ycf1 PF05758.7 ETS62123.1 - 4.6 4.8 6.6 6.4 4.3 4.6 1.3 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 ETS62123.1 - 5 5.8 10.0 8.2 5.1 6.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Yippee-Mis18 PF03226.9 ETS62124.1 - 4.8e-20 71.3 0.1 7.2e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly API5 PF05918.6 ETS62124.1 - 3.6 5.9 6.8 5.1 5.4 4.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Redoxin PF08534.5 ETS62125.1 - 2.6e-34 117.8 0.1 3.8e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ETS62125.1 - 2.2e-08 33.8 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Aa_trans PF01490.13 ETS62126.1 - 3.7e-80 269.4 32.9 4.5e-80 269.1 22.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sigma70_ner PF04546.8 ETS62126.1 - 0.067 12.7 1.6 0.13 11.9 1.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETS62126.1 - 0.09 12.2 8.7 0.34 10.4 5.9 1.8 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETS62126.1 - 1.3 9.2 13.0 3.7 7.8 9.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 ETS62126.1 - 1.9 6.3 5.9 2.5 5.9 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 ETS62126.1 - 4.8 6.3 7.6 8.2 5.5 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3395 PF11875.3 ETS62127.1 - 5.8e-34 116.9 0.0 1e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 ETS62127.1 - 6.3e-22 77.0 1.0 1.1e-21 76.3 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Med5 PF08689.5 ETS62128.1 - 8.8e-28 96.5 0.0 1.1e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Mediator complex subunit Med5 Amidohydro_1 PF01979.15 ETS62129.1 - 2e-36 126.3 0.0 1.4e-17 64.3 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.6 ETS62129.1 - 0.00063 19.0 0.1 0.15 11.2 0.1 3.1 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS62129.1 - 0.0015 18.2 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase PAPS_reduct PF01507.14 ETS62130.1 - 5.8e-37 127.1 0.0 1.1e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Atg14 PF10186.4 ETS62131.1 - 1.4e-17 63.6 0.2 2.6e-17 62.7 0.2 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Tim17 PF02466.14 ETS62132.1 - 0.042 13.8 0.7 0.042 13.8 0.5 2.9 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Tektin PF03148.9 ETS62132.1 - 0.1 11.0 1.4 0.23 9.9 1.0 1.5 1 0 0 1 1 1 0 Tektin family Gly-zipper_OmpA PF13436.1 ETS62132.1 - 0.73 9.4 6.9 6.3 6.4 0.8 2.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Paramyx_P_V_C PF03210.8 ETS62132.1 - 2 8.2 5.4 15 5.4 1.1 2.8 2 1 1 3 3 3 0 Paramyxovirus P/V phosphoprotein C-terminal Ribosomal_L36 PF00444.13 ETS62133.1 - 1.7e-22 79.1 7.7 2.6e-22 78.5 5.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 VBS PF08913.5 ETS62133.1 - 0.052 13.7 1.8 0.06 13.5 1.2 1.1 1 0 0 1 1 1 0 Vinculin Binding Site Ctf8 PF09696.5 ETS62134.1 - 1.2e-18 67.1 0.3 7.8e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Ctf8 DUF370 PF04025.7 ETS62134.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF370) PapD-like PF14874.1 ETS62135.1 - 4.6e-07 29.7 0.1 0.16 11.9 0.1 4.8 5 0 0 5 5 5 3 Flagellar-associated PapD-like PUF PF00806.14 ETS62137.1 - 1.4e-09 36.9 0.0 0.0013 18.1 0.0 6.0 7 0 0 7 7 7 2 Pumilio-family RNA binding repeat Ribosomal_S17e PF00833.13 ETS62137.1 - 0.022 14.5 2.8 0.28 10.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal S17 Frag1 PF10277.4 ETS62139.1 - 1.3e-35 122.8 6.3 1.3e-35 122.8 4.4 2.5 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family TRAM_LAG1_CLN8 PF03798.11 ETS62142.1 - 1.2e-28 100.0 27.9 1.2e-28 100.0 19.3 2.2 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 ETS62142.1 - 6.6e-14 51.1 0.0 6.6e-14 51.1 0.0 2.6 3 1 0 3 3 3 1 TRAM1-like protein Succ_CoA_lig PF13607.1 ETS62142.1 - 0.039 13.5 1.0 0.084 12.4 0.7 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Herpes_capsid PF06112.6 ETS62142.1 - 2.7 8.0 6.9 14 5.7 3.6 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Mid2 PF04478.7 ETS62143.1 - 0.087 12.2 0.1 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.1 ETS62143.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DAP10 PF07213.6 ETS62143.1 - 0.66 9.7 0.0 0.66 9.7 0.0 2.5 2 1 1 3 3 3 0 DAP10 membrane protein DUF1279 PF06916.8 ETS62144.1 - 6e-23 80.9 0.0 9.6e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L13e PF01294.13 ETS62145.1 - 1.8e-65 219.7 7.8 2.4e-65 219.3 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Herpes_US12 PF05363.7 ETS62145.1 - 0.79 10.2 3.4 5.4 7.5 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus US12 family HAD_2 PF13419.1 ETS62146.1 - 1.2e-15 58.1 0.0 2.4e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS62146.1 - 6.3e-12 46.3 0.0 1.1e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS62146.1 - 2.9e-09 36.5 0.0 6.6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 ETS62146.1 - 0.019 15.1 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS62146.1 - 0.11 12.0 0.1 0.73 9.3 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETS62146.1 - 0.15 11.9 0.0 1.2 9.1 0.0 2.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase His_Phos_1 PF00300.17 ETS62148.1 - 4.1e-20 72.4 0.0 7.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dus PF01207.12 ETS62149.1 - 3e-40 137.9 0.4 4.7e-40 137.3 0.3 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyridox_oxase_2 PF12766.2 ETS62149.1 - 9e-24 83.6 0.0 3.2e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Vps39_1 PF10366.4 ETS62150.1 - 6e-30 103.4 0.1 2e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 ETS62150.1 - 7.9e-29 100.0 0.2 1.6e-28 99.0 0.2 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 ETS62150.1 - 9.6e-15 54.7 0.0 9.3e-05 21.9 0.0 3.3 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.15 ETS62150.1 - 1.6e-07 31.0 0.1 0.0028 17.2 0.0 3.6 3 1 0 3 3 3 2 Region in Clathrin and VPS Apc3 PF12895.2 ETS62150.1 - 0.011 15.8 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS62150.1 - 0.026 14.8 1.8 0.14 12.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Med3 PF11593.3 ETS62150.1 - 0.11 11.6 9.0 0.45 9.7 6.2 2.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RHS PF03527.9 ETS62150.1 - 0.17 11.6 0.3 0.4 10.4 0.2 1.6 1 0 0 1 1 1 0 RHS protein TPR_12 PF13424.1 ETS62150.1 - 5 7.1 8.4 3.4 7.6 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Aminotran_3 PF00202.16 ETS62151.1 - 1.9e-31 109.1 0.0 1.4e-16 60.2 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.1 ETS62151.1 - 5.6e-25 88.1 0.0 1.1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DGCR6 PF07324.6 ETS62152.1 - 0.0003 20.3 1.3 0.00054 19.5 0.9 1.4 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein HemX PF04375.9 ETS62152.1 - 0.0065 15.1 1.9 0.011 14.3 1.3 1.3 1 0 0 1 1 1 1 HemX Nsp1_C PF05064.8 ETS62152.1 - 0.15 11.6 4.0 3.4 7.3 0.2 2.8 2 1 1 3 3 3 0 Nsp1-like C-terminal region THUMP PF02926.12 ETS62153.1 - 6.8e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Cwf_Cwc_15 PF04889.7 ETS62153.1 - 4.3 6.9 10.7 0.59 9.7 2.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein HEAT PF02985.17 ETS62154.1 - 6.8e-07 28.8 21.9 0.047 13.7 0.0 9.7 8 1 1 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 ETS62154.1 - 7.1e-07 29.5 25.2 0.13 12.8 0.1 10.3 9 1 2 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 ETS62154.1 - 0.0003 19.2 1.9 0.012 13.9 0.0 3.9 4 1 0 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 ETS62154.1 - 0.0015 18.3 0.0 6.8 6.5 0.0 4.3 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETS62154.1 - 0.0016 18.8 0.0 0.25 11.7 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 ETS62154.1 - 0.0052 16.5 3.8 0.02 14.7 0.2 3.8 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS62154.1 - 0.032 14.5 0.0 0.032 14.5 0.0 9.5 8 3 2 10 10 10 0 HEAT repeats DUF3245 PF11595.3 ETS62154.1 - 0.051 13.8 0.3 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) UCH PF00443.24 ETS62155.1 - 8.1e-40 136.6 0.0 2.2e-39 135.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 ETS62155.1 - 8e-19 66.8 1.8 8e-19 66.8 1.2 3.3 3 0 0 3 3 3 1 A repeated domain in UCH-protein UCH_1 PF13423.1 ETS62155.1 - 5.3e-10 39.2 0.0 0.0013 18.2 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CENP-F_leu_zip PF10473.4 ETS62155.1 - 0.49 10.2 4.8 2.9 7.7 0.1 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps8 PF12816.2 ETS62157.1 - 1.1e-50 171.6 0.0 9.5e-50 168.5 0.0 2.3 1 1 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.27 ETS62157.1 - 0.11 12.4 0.3 0.4 10.6 0.2 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat dUTPase PF00692.14 ETS62158.1 - 5.8e-43 145.4 0.0 7.9e-43 145.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase Dynamin_N PF00350.18 ETS62159.1 - 5.5e-43 146.6 0.0 2.4e-42 144.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 ETS62159.1 - 3.4e-06 26.0 0.1 0.00035 19.4 0.0 2.5 2 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 ETS62159.1 - 0.00026 20.9 0.0 0.0029 17.5 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 ETS62159.1 - 0.0045 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 ETS62159.1 - 0.032 14.2 0.2 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 ETS62159.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 ETS62160.1 - 2.8e-78 262.9 10.5 2.1e-77 260.0 7.3 1.9 1 1 0 1 1 1 1 Cation efflux family PC_rep PF01851.17 ETS62161.1 - 3.2e-18 64.8 17.4 0.0034 17.5 0.0 8.6 8 0 0 8 8 8 5 Proteasome/cyclosome repeat Bac_surface_Ag PF01103.18 ETS62164.1 - 4.6e-34 118.3 0.0 1.8e-33 116.3 0.0 1.8 1 1 0 1 1 1 1 Surface antigen RNA_pol_Rbc25 PF08292.7 ETS62165.1 - 1e-39 135.4 0.0 1.4e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 ETS62165.1 - 5.5e-19 68.0 0.0 9.6e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RhoGAP PF00620.22 ETS62166.1 - 4.3e-37 127.0 0.0 6.5e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 ETS62166.1 - 0.00086 18.2 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF1741 PF08427.5 ETS62169.1 - 3.6e-47 160.8 0.0 5.6e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) SEP PF08059.8 ETS62170.1 - 2.8e-26 91.6 0.0 5.6e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 ETS62170.1 - 3e-18 65.6 0.0 4.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 ETS62170.1 - 1.4e-15 56.5 0.3 2.4e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Tim17 PF02466.14 ETS62171.1 - 5.6e-14 52.2 11.1 8.4e-14 51.7 7.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 ETS62171.1 - 0.73 9.1 6.4 0.57 9.5 3.5 1.5 1 1 1 2 2 2 0 5TMR of 5TMR-LYT tRNA_bind PF01588.15 ETS62172.1 - 2.7e-27 94.4 0.0 6.6e-27 93.1 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 ETS62172.1 - 0.00022 21.1 1.9 0.00036 20.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS62172.1 - 0.00053 19.8 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS62172.1 - 0.00062 20.2 0.4 0.002 18.5 0.0 2.0 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain U79_P34 PF03064.11 ETS62172.1 - 0.14 11.6 8.5 0.22 11.0 5.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2413 PF10310.4 ETS62172.1 - 0.22 10.3 8.6 0.34 9.6 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) GAGA_bind PF06217.7 ETS62172.1 - 0.25 11.2 4.4 0.38 10.6 3.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 ETS62172.1 - 0.25 10.4 7.9 0.38 9.8 5.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 ETS62172.1 - 6.1 6.6 12.1 11 5.8 8.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 adh_short PF00106.20 ETS62173.1 - 9.7e-05 22.3 0.2 6.1 6.7 0.0 3.5 3 0 0 3 3 3 3 short chain dehydrogenase UDPGP PF01704.13 ETS62175.1 - 1.4e-48 165.4 0.0 2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_L4 PF00573.17 ETS62176.1 - 6.9e-45 152.7 0.7 1.2e-44 152.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 ETS62176.1 - 1.2e-28 98.7 4.1 2e-28 98.0 0.5 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Aconitase PF00330.15 ETS62177.1 - 6.3e-176 585.4 0.1 1.4e-175 584.3 0.1 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS62177.1 - 2.7e-43 147.1 0.0 5.7e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 ETS62177.1 - 0.042 12.4 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MFS_1 PF07690.11 ETS62178.1 - 1.9e-29 102.5 49.4 1.6e-27 96.1 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS62178.1 - 6.9e-20 71.0 14.2 3.5e-19 68.7 9.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Chalcone PF02431.10 ETS62179.1 - 7e-41 139.8 0.0 9.4e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Anti-adapt_IraP PF10796.4 ETS62179.1 - 0.15 12.4 0.3 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Acetyltransf_1 PF00583.19 ETS62180.1 - 1.3e-15 57.2 0.0 1.9e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS62180.1 - 5.3e-12 45.7 0.1 7.5e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS62180.1 - 0.00071 19.4 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS62180.1 - 0.002 17.8 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 ETS62180.1 - 0.0047 16.8 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS62180.1 - 0.015 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS62180.1 - 0.03 14.1 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase WEMBL PF05701.6 ETS62181.1 - 0.081 11.3 1.9 0.12 10.8 1.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SNARE PF05739.14 ETS62183.1 - 1.5e-06 27.7 0.6 1.5e-06 27.7 0.4 3.3 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 ETS62183.1 - 0.0083 16.1 2.7 0.64 10.1 0.3 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF1490 PF07371.7 ETS62183.1 - 2 8.4 4.7 0.58 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Peptidase_C6 PF00851.13 ETS62183.1 - 6.7 5.2 6.4 12 4.3 4.4 1.4 1 0 0 1 1 1 0 Helper component proteinase TPR_MLP1_2 PF07926.7 ETS62183.1 - 7.6 6.2 16.1 43 3.8 11.1 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 ETS62184.1 - 7.9e-18 64.1 9.4 1e-17 63.7 6.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit RasGAP_C PF03836.10 ETS62184.1 - 0.022 14.4 3.9 0.022 14.4 2.7 2.2 2 1 0 2 2 2 0 RasGAP C-terminus Suppressor_APC PF11414.3 ETS62184.1 - 0.027 14.2 3.3 0.027 14.2 2.3 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF904 PF06005.7 ETS62184.1 - 0.03 14.5 2.6 0.03 14.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) EMP24_GP25L PF01105.19 ETS62184.1 - 0.048 13.3 5.9 0.4 10.3 0.4 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MscS_porin PF12795.2 ETS62184.1 - 0.075 12.3 26.8 0.027 13.7 7.6 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4349 PF14257.1 ETS62184.1 - 0.15 11.2 8.3 0.37 9.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) FlaC_arch PF05377.6 ETS62184.1 - 0.16 11.8 3.1 2.5 8.0 0.2 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 ETS62184.1 - 0.37 11.2 9.6 3.5 8.1 0.8 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 ETS62184.1 - 0.53 10.5 8.6 2.7 8.3 1.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 ETS62184.1 - 0.56 10.5 7.5 2.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3584 PF12128.3 ETS62184.1 - 0.59 7.4 15.6 1.2 6.4 10.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2408 PF10303.4 ETS62184.1 - 0.62 10.1 5.5 1 9.4 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Atg14 PF10186.4 ETS62184.1 - 0.75 8.6 12.4 0.98 8.2 0.8 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3847 PF12958.2 ETS62184.1 - 1 9.1 9.6 0.69 9.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DivIC PF04977.10 ETS62184.1 - 3.3 7.2 14.6 4.8 6.7 3.3 2.4 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 ETS62184.1 - 3.3 7.2 18.0 90 2.5 12.5 2.0 1 1 0 1 1 1 0 IncA protein Osmo_CC PF08946.5 ETS62184.1 - 3.5 7.7 6.9 0.75 9.8 1.5 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil XhlA PF10779.4 ETS62184.1 - 4.5 7.2 7.9 0.22 11.4 0.8 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Baculo_PEP_C PF04513.7 ETS62184.1 - 4.5 7.0 12.5 58 3.5 7.6 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 ETS62184.1 - 4.6 7.0 14.9 0.24 11.2 4.6 2.0 2 0 0 2 2 2 0 Tropomyosin like FlxA PF14282.1 ETS62184.1 - 5 7.1 22.8 2.6 8.0 2.2 2.3 2 0 0 2 2 2 0 FlxA-like protein NTR2 PF15458.1 ETS62184.1 - 7.8 5.6 14.6 4.7 6.3 3.0 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 RhoGEF PF00621.15 ETS62185.1 - 1.2e-12 48.1 0.0 2.2e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CSTF2_hinge PF14327.1 ETS62186.1 - 1e-30 105.6 2.0 1e-30 105.6 1.4 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 ETS62186.1 - 3.5e-23 81.0 0.1 5.8e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS62186.1 - 4.3e-17 61.8 0.0 8.8e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 ETS62186.1 - 3.2e-11 42.3 6.4 3.2e-11 42.3 4.4 2.0 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 ETS62186.1 - 2.1e-07 30.7 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2315 PF10231.4 ETS62187.1 - 1.8e-14 53.7 1.4 6.9e-10 38.8 0.6 2.5 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) DUF566 PF04484.7 ETS62187.1 - 4.6 6.6 21.0 0.68 9.3 11.4 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF566) TFIIF_alpha PF05793.7 ETS62188.1 - 10 4.3 16.9 0.13 10.5 6.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4345 PF14248.1 ETS62189.1 - 1.6e-10 40.5 0.4 2.6e-10 39.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF3087 PF11286.3 ETS62190.1 - 0.068 12.3 0.1 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF1674 PF07896.7 ETS62191.1 - 6.7e-13 48.6 6.4 1.3e-12 47.6 4.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) AT_hook PF02178.14 ETS62192.1 - 0.15 11.8 5.0 0.56 10.0 3.5 2.1 1 0 0 1 1 1 0 AT hook motif IncA PF04156.9 ETS62192.1 - 2.3 7.7 12.8 3.9 7.0 8.9 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 ETS62192.1 - 3 6.8 11.6 4.7 6.1 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 RQC PF09382.5 ETS62193.1 - 2.8e-24 84.8 0.7 6.4e-24 83.7 0.5 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 ETS62193.1 - 1.9e-21 76.2 0.0 5.5e-21 74.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS62193.1 - 5.2e-19 67.9 0.0 4.7e-18 64.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 ETS62193.1 - 2.5e-05 23.8 0.0 5.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Helicase_Sgs1 PF11408.3 ETS62193.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase Prenyltrans PF00432.16 ETS62194.1 - 8.1 6.1 6.7 4.5 6.9 0.1 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat B56 PF01603.15 ETS62195.1 - 5.8e-171 568.6 9.6 7.1e-171 568.3 6.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) LamB_YcsF PF03746.11 ETS62196.1 - 1.4e-69 233.8 0.0 3.4e-69 232.5 0.0 1.5 1 1 0 1 1 1 1 LamB/YcsF family Cornichon PF03311.9 ETS62197.1 - 2.5e-52 176.3 11.8 3e-52 176.1 8.2 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 ETS62197.1 - 0.96 8.9 10.2 3.6 7.0 7.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) MFS_2 PF13347.1 ETS62198.1 - 1.3e-06 27.1 5.0 1.9e-05 23.2 2.5 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 ETS62198.1 - 0.1 12.4 0.0 0.1 12.4 0.0 4.4 4 1 1 5 5 5 0 MFS_1 like family GTP_EFTU PF00009.22 ETS62199.1 - 6.2e-43 146.4 0.0 8.2e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ETS62199.1 - 6.9e-28 96.6 0.0 1.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETS62199.1 - 3.7e-19 68.3 0.0 8.1e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 ETS62199.1 - 5.4e-09 36.5 0.0 9.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS62199.1 - 3.6e-07 30.1 0.0 8.6e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 ETS62199.1 - 3.8e-05 23.4 0.0 8.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 ETS62199.1 - 6.9e-05 22.8 0.1 0.00015 21.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 ETS62199.1 - 0.00047 20.0 0.1 1.1 9.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Ras PF00071.17 ETS62199.1 - 0.00081 18.8 0.0 0.0023 17.3 0.0 1.8 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 ETS62199.1 - 0.0072 15.5 0.0 0.019 14.2 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit CbiA PF01656.18 ETS62199.1 - 0.018 14.4 0.1 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 ETS62199.1 - 0.046 13.2 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 ETS62199.1 - 0.078 12.2 0.2 3.5 6.8 0.2 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B Glutaredoxin PF00462.19 ETS62200.1 - 2.7e-16 59.2 0.1 3.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin bZIP_1 PF00170.16 ETS62201.1 - 4.4e-06 26.5 10.1 4.4e-06 26.5 7.0 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 ETS62201.1 - 0.0049 16.6 5.9 0.0098 15.7 4.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 ETS62201.1 - 0.052 13.8 8.2 0.07 13.4 3.3 2.9 3 0 0 3 3 3 0 bZIP Maf transcription factor Fasciclin PF02469.17 ETS62202.1 - 3.1e-23 82.1 0.1 3.1e-14 53.0 0.0 3.4 3 1 0 3 3 3 3 Fasciclin domain DAG_kinase_N PF14513.1 ETS62202.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus COesterase PF00135.23 ETS62203.1 - 3.4e-78 263.6 0.0 9.5e-78 262.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS62203.1 - 5.5e-07 29.3 3.6 0.0022 17.5 0.3 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS62204.1 - 4e-12 46.5 2.5 4e-12 46.5 1.7 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS62204.1 - 2.7e-07 30.4 0.1 6e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 ETS62204.1 - 0.00049 19.0 0.0 0.00075 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 ETS62204.1 - 0.00063 19.0 0.0 0.049 12.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS62204.1 - 0.0011 18.6 0.0 0.003 17.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 ETS62204.1 - 0.025 13.6 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2423 PF10338.4 ETS62205.1 - 6.6e-15 54.8 4.9 1.1e-14 54.1 3.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ank_2 PF12796.2 ETS62206.1 - 7.1e-45 151.2 5.1 1.4e-17 63.8 0.1 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS62206.1 - 2e-38 128.3 9.8 1.4e-07 30.9 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 ETS62206.1 - 1.1e-34 118.1 2.0 3.6e-12 46.4 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 ETS62206.1 - 2.8e-32 112.5 6.4 1.1e-19 71.3 0.1 2.2 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 ETS62206.1 - 3.6e-27 93.7 8.8 9.3e-05 22.5 0.0 7.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS62206.1 - 4.1e-27 91.5 5.7 0.00049 20.0 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat GDPD PF03009.12 ETS62206.1 - 1.8e-13 50.5 0.0 6.8e-13 48.7 0.0 2.0 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CRM1_C PF08767.6 ETS62208.1 - 5.8e-128 426.2 1.8 1.4e-127 425.0 0.0 2.5 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 ETS62208.1 - 3.6e-41 140.5 0.8 3.6e-41 140.5 0.5 3.7 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 ETS62208.1 - 9.5e-15 54.2 1.5 4.5e-14 52.1 0.7 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain WD40 PF00400.27 ETS62209.1 - 3.1e-28 96.5 11.0 3.9e-08 32.8 0.5 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Fungal_trans PF04082.13 ETS62209.1 - 2.3e-12 46.3 0.0 4.2e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS62209.1 - 9.8e-06 25.6 7.5 0.0064 16.7 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type CLTH PF10607.4 ETS62209.1 - 0.00046 19.8 0.1 0.00097 18.8 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-C2H2_4 PF13894.1 ETS62209.1 - 0.0016 18.6 6.6 0.081 13.2 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger LisH PF08513.6 ETS62209.1 - 0.23 11.2 0.2 0.51 10.2 0.1 1.6 1 0 0 1 1 1 0 LisH zf-H2C2_2 PF13465.1 ETS62209.1 - 0.84 10.0 3.7 0.65 10.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Nucleoporin_C PF03177.9 ETS62210.1 - 2.6e-87 293.7 1.4 3.7e-87 293.2 1.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 ETS62210.1 - 2.5e-14 52.8 0.0 4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like FAM180 PF15173.1 ETS62214.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 FAM180 family DUF2786 PF10979.3 ETS62215.1 - 1.6e-11 43.7 1.5 1.6e-11 43.7 1.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Guanylate_kin PF00625.16 ETS62216.1 - 4e-58 195.8 0.0 4.8e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 ETS62216.1 - 8.4e-08 32.4 0.0 2.4e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS62216.1 - 1.2e-05 25.4 0.0 6.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS62216.1 - 2.8e-05 24.4 0.0 0.00072 19.8 0.0 2.5 2 1 1 3 3 3 1 AAA domain DUF258 PF03193.11 ETS62216.1 - 7.4e-05 21.9 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS62216.1 - 9.5e-05 23.2 0.1 0.00023 21.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS62216.1 - 0.00013 21.8 0.0 0.002 17.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS62216.1 - 0.00064 19.6 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS62216.1 - 0.00095 18.9 0.1 0.0035 17.0 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 ETS62216.1 - 0.0014 18.0 0.1 0.006 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 ETS62216.1 - 0.0016 17.9 0.1 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 ETS62216.1 - 0.0019 17.8 0.0 0.0066 16.1 0.0 1.9 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 ETS62216.1 - 0.002 18.4 0.0 0.0028 17.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.12 ETS62216.1 - 0.0024 17.2 0.0 0.014 14.7 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase RNA_helicase PF00910.17 ETS62216.1 - 0.0025 17.9 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 ETS62216.1 - 0.0026 17.6 0.0 0.006 16.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 ETS62216.1 - 0.0029 17.5 0.1 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 ETS62216.1 - 0.0029 17.3 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 NTPase Miro PF08477.8 ETS62216.1 - 0.008 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_5 PF07728.9 ETS62216.1 - 0.0095 15.6 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETS62216.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 ETS62216.1 - 0.025 13.2 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 ETS62216.1 - 0.034 13.1 0.0 0.044 12.7 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.17 ETS62216.1 - 0.039 12.7 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 ETS62216.1 - 0.043 12.7 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 ETS62216.1 - 0.054 12.2 0.1 0.083 11.6 0.0 1.4 1 0 0 1 1 1 0 ArgK protein PCMT PF01135.14 ETS62217.1 - 7.4e-66 221.6 0.0 8.6e-66 221.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 ETS62217.1 - 4.1e-08 33.7 0.0 6.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS62217.1 - 1.6e-07 31.0 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS62217.1 - 3.5e-06 27.2 0.0 7.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS62217.1 - 1.4e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS62217.1 - 3.4e-05 23.8 0.1 6.1e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS62217.1 - 4.2e-05 23.9 0.1 0.00023 21.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 ETS62217.1 - 0.001 18.2 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 ETS62217.1 - 0.0042 16.7 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS62217.1 - 0.043 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 ETS62217.1 - 0.074 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 ETS62217.1 - 0.078 11.6 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) UQ_con PF00179.21 ETS62218.1 - 4.9e-39 132.9 0.0 6.5e-39 132.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETS62218.1 - 0.017 15.0 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 ETS62218.1 - 0.03 14.0 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.1 ETS62218.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Exo_endo_phos PF03372.18 ETS62219.1 - 6.9e-24 85.1 0.2 9e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 ETS62220.1 - 7.6e-17 60.4 8.7 4.3e-05 23.2 0.7 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat LEA_2 PF03168.8 ETS62221.1 - 0.00041 20.6 0.1 0.00095 19.5 0.1 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 ETS62221.1 - 0.0025 17.0 0.9 0.0048 16.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Peptidase_S8 PF00082.17 ETS62222.1 - 1e-56 192.1 1.9 1.5e-56 191.6 1.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 ETS62222.1 - 4.7e-28 96.8 0.1 1e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain P12 PF12669.2 ETS62222.1 - 0.14 12.3 0.4 0.85 9.8 0.5 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Serglycin PF04360.7 ETS62222.1 - 6.8 6.4 8.8 0.32 10.7 1.8 1.9 2 0 0 2 2 2 0 Serglycin MIP PF00230.15 ETS62223.1 - 1e-44 152.7 13.4 1.4e-44 152.2 9.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein hNIFK_binding PF12196.3 ETS62223.1 - 0.016 14.5 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK CPSF100_C PF13299.1 ETS62224.1 - 2.5e-23 83.0 0.1 7.5e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 ETS62224.1 - 2.9e-22 78.9 0.0 6.6e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 ETS62224.1 - 1.4e-05 24.7 0.0 3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3553 PF12073.3 ETS62224.1 - 0.013 14.8 0.0 6.1 6.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3553) Lactamase_B PF00753.22 ETS62224.1 - 0.016 14.8 0.2 0.11 12.0 0.1 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF3740 PF12548.3 ETS62224.1 - 0.029 14.6 0.3 1.3 9.3 0.3 2.6 2 0 0 2 2 2 0 Sulfatase protein PTCB-BRCT PF12738.2 ETS62225.1 - 2.9e-05 23.8 0.2 8.1e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain fn3 PF00041.16 ETS62225.1 - 0.00044 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain BRCT PF00533.21 ETS62225.1 - 0.00059 19.9 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 ETS62225.1 - 0.014 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) F-box PF00646.28 ETS62226.1 - 1.3e-07 31.0 0.3 2.3e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS62226.1 - 3.5e-07 29.8 0.8 6.6e-07 28.9 0.5 1.4 1 0 0 1 1 1 1 F-box-like Lactamase_B_3 PF13483.1 ETS62227.1 - 5.7e-08 32.6 0.0 3.3e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain P34-Arc PF04045.9 ETS62228.1 - 8.1e-105 349.4 0.0 1e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF2361 PF10153.4 ETS62229.1 - 0.058 13.5 3.6 0.092 12.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) CRA PF06589.6 ETS62229.1 - 0.14 11.4 0.4 0.28 10.4 0.3 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) FYDLN_acid PF09538.5 ETS62229.1 - 0.24 12.0 8.2 0.11 13.0 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Apc15p PF05841.6 ETS62229.1 - 2.4 8.9 8.9 0.17 12.6 1.2 2.3 2 1 0 2 2 2 0 Apc15p protein Macoilin PF09726.4 ETS62229.1 - 3.4 5.8 7.4 4.8 5.3 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein TEA PF01285.13 ETS62231.1 - 5.8e-36 124.5 0.0 2.9e-35 122.2 0.0 2.1 1 1 0 1 1 1 1 TEA/ATTS domain family Pkinase PF00069.20 ETS62232.1 - 4e-50 170.3 0.0 6.3e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62232.1 - 3.2e-45 154.2 0.0 4.4e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sec66 PF09802.4 ETS62233.1 - 3.3e-48 163.5 0.0 5e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3708 PF12501.3 ETS62233.1 - 0.09 12.6 5.4 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter PAT1 PF09770.4 ETS62233.1 - 0.29 9.3 17.0 0.36 9.0 11.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3761 PF12587.3 ETS62233.1 - 0.62 10.2 2.6 1.1 9.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) RasGEF PF00617.14 ETS62234.1 - 1.8e-63 213.6 0.9 6.3e-63 211.9 0.1 2.2 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 ETS62234.1 - 9.2e-29 99.6 0.2 2.1e-28 98.4 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 ETS62234.1 - 4.9e-14 51.4 0.1 9.7e-14 50.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS62234.1 - 3.4e-12 45.7 0.1 6.8e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS62234.1 - 7.5e-11 41.3 0.0 1.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAE2 PF08573.5 ETS62235.1 - 8.3e-11 42.4 5.3 5.6e-09 36.5 0.5 3.2 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus UEV PF05743.8 ETS62236.1 - 2.7e-38 130.3 0.0 4.1e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 ETS62236.1 - 2.4e-27 94.3 2.2 2.4e-27 94.2 0.3 1.8 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.21 ETS62236.1 - 0.0025 17.2 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-Mss51 PF13824.1 ETS62237.1 - 4e-22 77.8 1.0 8.6e-22 76.7 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Epimerase PF01370.16 ETS62238.1 - 9e-43 146.3 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS62238.1 - 1e-09 37.7 0.0 7.3e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 ETS62238.1 - 2e-09 36.5 0.0 3.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS62238.1 - 2.3e-06 26.7 0.0 5.1e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ETS62238.1 - 5e-05 22.3 0.1 0.00097 18.1 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS62238.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 ETS62238.1 - 0.027 14.3 0.0 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Lactamase_B_2 PF12706.2 ETS62239.1 - 2.6e-25 89.1 0.0 1.2e-24 87.0 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS62239.1 - 2.2e-08 33.9 0.0 1.4e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 ETS62240.1 - 1.3e-21 76.6 0.0 2.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS62240.1 - 1.9e-06 27.6 8.7 3.9e-06 26.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4188 PF13826.1 ETS62241.1 - 1.2e-23 83.4 0.0 1.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Filament PF00038.16 ETS62242.1 - 0.0053 16.2 0.8 0.013 15.0 0.6 1.5 1 0 0 1 1 1 1 Intermediate filament protein HAP1_N PF04849.8 ETS62242.1 - 0.018 13.9 2.5 0.63 8.9 0.1 2.8 3 0 0 3 3 3 0 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.7 ETS62242.1 - 0.23 11.2 8.1 0.23 11.2 0.6 2.8 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 ETS62242.1 - 5.1 6.6 12.3 1.6 8.2 0.3 3.0 2 1 1 3 3 3 0 Septum formation initiator FlgN PF05130.7 ETS62242.1 - 7.3 6.8 15.1 0.28 11.4 0.2 3.0 3 0 0 3 3 3 0 FlgN protein CHORD PF04968.7 ETS62243.1 - 3.3e-42 142.5 12.1 1.7e-24 85.8 2.7 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 ETS62243.1 - 4.5e-07 30.3 0.0 7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.14 ETS62243.1 - 0.0056 16.2 6.5 0.18 11.4 1.3 3.0 2 1 0 2 2 2 2 BTK motif DUF2733 PF10813.3 ETS62243.1 - 0.7 9.5 3.9 11 5.6 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Ribosomal_60s PF00428.14 ETS62243.1 - 8.9 6.7 12.9 0.91 9.9 5.4 2.0 1 1 1 2 2 2 0 60s Acidic ribosomal protein AAA PF00004.24 ETS62244.1 - 5.3e-14 52.5 0.0 2.4e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 ETS62244.1 - 3.9e-05 22.5 0.3 0.26 9.9 0.0 2.9 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 ETS62244.1 - 0.00021 20.4 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETS62244.1 - 0.00027 21.7 0.0 0.0011 19.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS62244.1 - 0.00029 20.7 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS62244.1 - 0.00049 19.8 0.0 0.00049 19.8 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain AAA_16 PF13191.1 ETS62244.1 - 0.0015 18.5 0.0 0.88 9.5 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 ETS62244.1 - 0.0016 17.8 0.0 0.48 9.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS62244.1 - 0.019 15.0 0.0 0.081 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS62244.1 - 0.037 13.8 0.6 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS62244.1 - 0.082 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS62244.1 - 0.084 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETS62244.1 - 0.13 11.9 0.3 0.6 9.8 0.0 2.1 1 1 1 2 2 2 0 NTPase KaiC PF06745.8 ETS62244.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 ETS62244.1 - 0.23 10.2 0.0 0.42 9.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Carboxyl_trans PF01039.17 ETS62245.1 - 1e-145 485.8 0.3 1.3e-145 485.5 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 ETS62245.1 - 0.0076 15.4 0.1 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) AAA PF00004.24 ETS62246.1 - 8.9e-17 61.5 0.0 2.2e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS62246.1 - 4.8e-05 23.1 0.1 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS62246.1 - 7.4e-05 23.5 0.0 0.00017 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS62246.1 - 7.6e-05 22.8 1.4 0.002 18.2 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.1 ETS62246.1 - 0.00015 21.4 0.3 0.00015 21.4 0.2 2.7 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 ETS62246.1 - 0.00023 21.1 3.0 0.00061 19.8 0.0 3.1 3 1 1 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 ETS62246.1 - 0.0042 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 ETS62246.1 - 0.012 15.5 0.0 0.031 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 ETS62246.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS62246.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETS62246.1 - 0.024 13.8 0.1 0.053 12.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 ETS62246.1 - 0.041 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 ETS62246.1 - 0.052 12.2 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Na_Ca_ex PF01699.19 ETS62247.1 - 3.5e-16 59.0 9.6 5.2e-16 58.5 6.7 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein HNH_3 PF13392.1 ETS62248.1 - 4.9e-14 51.4 0.6 8.5e-07 28.2 0.1 2.4 2 0 0 2 2 2 2 HNH endonuclease Zn_clus PF00172.13 ETS62249.1 - 0.0013 18.5 8.6 0.0028 17.5 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF508 PF04370.7 ETS62249.1 - 0.061 12.9 0.9 1.9 8.0 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF508) Peroxidase_2 PF01328.12 ETS62251.1 - 1.6e-14 53.3 1.5 2e-13 49.6 0.9 2.3 1 1 0 1 1 1 1 Peroxidase, family 2 Pro_isomerase PF00160.16 ETS62252.1 - 8.9e-50 168.9 0.0 2.7e-49 167.3 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 ETS62252.1 - 0.00027 20.7 5.2 0.0015 18.3 0.3 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Mito_carr PF00153.22 ETS62253.1 - 1.4e-46 156.0 9.6 1.5e-15 56.6 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein CH PF00307.26 ETS62254.1 - 6.2e-41 138.8 0.0 1e-21 76.9 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 ETS62254.1 - 2e-20 72.5 0.0 4.9e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 ETS62254.1 - 2.2e-13 49.6 0.2 1.6e-09 37.2 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain Spectrin PF00435.16 ETS62254.1 - 5.2e-07 29.9 2.3 0.0071 16.6 0.3 3.0 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.1 ETS62254.1 - 0.00012 21.6 0.0 0.00075 19.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 ETS62254.1 - 0.0035 16.5 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 EF hand Baculo_PEP_C PF04513.7 ETS62254.1 - 0.008 15.9 0.3 0.046 13.5 0.2 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_5 PF13202.1 ETS62254.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 EF hand Cofilin_ADF PF00241.15 ETS62256.1 - 2.6e-44 150.1 1.2 2.9e-44 149.9 0.8 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Na_H_Exchanger PF00999.16 ETS62258.1 - 2.1e-59 201.0 40.9 3.1e-59 200.4 28.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PP2C PF00481.16 ETS62259.1 - 6e-80 268.3 0.0 8.5e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.27 ETS62261.1 - 2.8e-27 93.5 0.4 3.6e-08 32.9 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Gmad1 PF10647.4 ETS62261.1 - 5.5e-05 22.6 0.1 0.00011 21.7 0.1 1.5 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 ETS62261.1 - 0.0026 15.9 0.3 0.0067 14.6 0.1 1.6 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETS62261.1 - 0.077 11.7 0.4 3.3 6.3 0.1 2.7 1 1 1 2 2 2 0 Nup133 N terminal like PH_5 PF15405.1 ETS62262.1 - 1.9 8.4 3.7 0.72 9.7 0.3 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain PH_10 PF15411.1 ETS62263.1 - 5e-30 104.0 0.0 9.1e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 ETS62263.1 - 3.7e-06 26.6 1.0 8.2e-06 25.5 0.7 1.6 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 ETS62263.1 - 0.0014 18.3 0.2 0.74 9.4 0.0 3.2 3 0 0 3 3 3 2 von Willebrand factor type A domain zf-RING_5 PF14634.1 ETS62263.1 - 0.0031 17.2 1.3 0.014 15.1 1.2 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS62263.1 - 0.0079 16.1 0.6 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS62263.1 - 0.018 14.6 0.2 0.039 13.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 ETS62263.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain zf-C3HC4_3 PF13920.1 ETS62263.1 - 0.062 12.9 0.8 0.18 11.5 0.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS62263.1 - 0.094 12.8 0.2 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger Ribonuc_red_lgC PF02867.10 ETS62265.1 - 2.3e-216 719.5 0.0 3e-216 719.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 ETS62265.1 - 4e-25 87.4 0.0 1.2e-24 85.9 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 ETS62265.1 - 2.7e-17 62.9 1.1 1.2e-16 60.8 0.2 2.6 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 ETS62265.1 - 0.0066 14.5 0.0 0.01 13.9 0.0 1.3 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase DUF1556 PF07590.6 ETS62266.1 - 0.055 13.6 2.1 0.069 13.3 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1556) Ufd2P_core PF10408.4 ETS62267.1 - 5.3e-185 616.2 0.0 6.3e-185 616.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 ETS62267.1 - 2.8e-28 97.6 0.2 7.7e-28 96.2 0.1 1.8 1 0 0 1 1 1 1 U-box domain Adeno_GP19K PF04881.8 ETS62267.1 - 0.18 11.5 0.1 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Adenovirus GP19K BCNT PF07572.7 ETS62268.1 - 1e-18 67.0 1.6 2.9e-18 65.5 1.1 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development COX4 PF02936.9 ETS62268.1 - 0.015 15.0 0.3 5.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF4505 PF14956.1 ETS62270.1 - 2.2e-27 95.9 0.0 3.2e-14 52.9 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4505) Yos1 PF08571.5 ETS62271.1 - 3.4e-28 97.5 0.9 5.4e-28 96.9 0.6 1.3 1 0 0 1 1 1 1 Yos1-like Ribosomal_S8 PF00410.14 ETS62271.1 - 4.4e-17 62.1 0.0 7.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8 MDMPI_C PF07398.6 ETS62271.1 - 0.078 13.5 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 MDMPI C-terminal domain DnaJ PF00226.26 ETS62272.1 - 3.4e-26 90.7 1.9 4.9e-26 90.2 1.3 1.2 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 ETS62272.1 - 1e-14 54.2 2.0 1.3e-11 44.2 0.0 3.5 2 2 1 3 3 3 2 DnaJ C terminal domain UDG PF03167.14 ETS62274.1 - 2.5e-15 56.2 0.0 4.8e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Macoilin PF09726.4 ETS62274.1 - 0.021 13.1 1.9 0.021 13.1 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Arrestin_N PF00339.24 ETS62275.1 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 ETS62275.1 - 0.034 13.6 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 Arrestin_N terminal like Aldedh PF00171.17 ETS62276.1 - 3.6e-156 520.1 0.1 4.4e-156 519.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 ETS62276.1 - 0.0084 15.3 0.0 0.03 13.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Ldh_2 PF02615.9 ETS62276.1 - 0.03 13.0 0.1 0.053 12.2 0.1 1.3 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase NDUFA12 PF05071.11 ETS62277.1 - 3.6e-25 88.4 1.7 5.5e-25 87.8 1.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 NIF PF03031.13 ETS62277.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Flavokinase PF01687.12 ETS62279.1 - 4.6e-35 120.2 0.0 1.1e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Riboflavin kinase DUF3678 PF12435.3 ETS62279.1 - 1.3 8.6 7.2 0.71 9.4 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) CAP PF00188.21 ETS62281.1 - 2.2e-13 50.7 2.6 2.2e-13 50.7 1.8 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Auxin_inducible PF02519.9 ETS62281.1 - 0.053 13.5 1.3 0.19 11.8 0.9 2.0 1 0 0 1 1 1 0 Auxin responsive protein NADH-G_4Fe-4S_3 PF10588.4 ETS62281.1 - 0.1 11.8 0.1 0.22 10.7 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region XPG_I PF00867.13 ETS62282.1 - 3.1e-11 43.1 0.4 1.6e-10 40.8 0.0 2.5 2 1 0 2 2 2 1 XPG I-region XPG_N PF00752.12 ETS62282.1 - 2.5e-06 27.6 0.0 4.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 ETS62282.1 - 1.4e-05 25.2 0.0 3.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Remorin_C PF03763.8 ETS62282.1 - 0.024 14.1 0.9 0.047 13.2 0.6 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region HHH_5 PF14520.1 ETS62282.1 - 0.043 13.9 0.8 0.14 12.3 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH PF00633.18 ETS62282.1 - 0.065 12.9 0.1 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3135 PF11333.3 ETS62282.1 - 0.75 10.0 3.3 1.7 8.8 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) V-ATPase_G PF03179.10 ETS62283.1 - 5.6e-34 116.5 15.0 7.5e-34 116.1 10.4 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 ETS62283.1 - 0.014 15.2 18.9 0.027 14.2 9.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) PAXIP1_C PF15364.1 ETS62283.1 - 0.034 14.0 6.0 0.06 13.2 4.2 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Seryl_tRNA_N PF02403.17 ETS62283.1 - 0.07 13.1 12.1 0.15 12.1 8.1 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3453 PF11935.3 ETS62284.1 - 1.9e-60 204.2 1.0 3.7e-60 203.3 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.3 ETS62284.1 - 2.1e-60 203.8 0.4 8.3e-60 201.8 0.0 2.3 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal Adaptin_N PF01602.15 ETS62284.1 - 0.015 13.6 9.5 0.12 10.6 1.8 3.6 3 1 0 3 3 3 0 Adaptin N terminal region OPT PF03169.10 ETS62285.1 - 1.4e-171 572.1 54.2 1.6e-171 571.9 37.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_3 PF01494.14 ETS62286.1 - 6e-88 295.2 0.0 8.3e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS62286.1 - 2.3e-53 180.2 0.0 4.4e-53 179.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 ETS62286.1 - 4.1e-05 22.2 0.1 7.5e-05 21.3 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS62286.1 - 0.00013 21.0 0.6 0.00046 19.2 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 ETS62286.1 - 0.00016 20.7 0.5 0.0062 15.4 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS62286.1 - 0.00065 19.6 1.8 0.0011 18.9 0.1 2.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS62286.1 - 0.00082 19.3 0.1 0.0022 17.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS62286.1 - 0.00084 18.2 0.2 0.0023 16.8 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 ETS62286.1 - 0.0021 17.1 0.1 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 ETS62286.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 ETS62286.1 - 0.032 14.6 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS62286.1 - 0.032 12.8 0.1 0.05 12.2 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 ETS62286.1 - 0.076 12.7 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 ETS62286.1 - 0.089 11.6 0.2 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 ETS62286.1 - 0.22 10.2 0.0 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase His_Phos_2 PF00328.17 ETS62287.1 - 5e-40 137.8 0.0 6.5e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sec7 PF01369.15 ETS62288.1 - 6.8e-63 211.7 0.0 1.7e-62 210.5 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETS62288.1 - 8.6e-57 191.2 4.9 8.6e-57 191.2 3.4 3.2 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 ETS62288.1 - 7.4e-32 108.7 6.5 3e-31 106.7 0.1 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Mob1_phocein PF03637.12 ETS62289.1 - 2.3e-73 245.5 0.1 2.7e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family E1-E2_ATPase PF00122.15 ETS62290.1 - 2e-52 177.5 2.7 2e-52 177.5 1.9 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 ETS62290.1 - 5.8e-21 75.8 0.5 2.2e-20 74.0 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 ETS62290.1 - 2e-16 60.0 8.7 2e-16 60.0 6.1 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 ETS62290.1 - 2.2e-14 52.6 0.1 4.5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 ETS62290.1 - 2.9e-14 53.6 0.2 2.5e-13 50.6 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS62290.1 - 2.3e-07 30.6 0.0 5.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS62290.1 - 0.002 17.7 0.1 0.0056 16.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acyl_transf_3 PF01757.17 ETS62291.1 - 2e-14 53.1 37.4 3.7e-14 52.3 25.9 1.4 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_16 PF00722.16 ETS62291.1 - 3.8e-06 26.3 0.1 6.5e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sel1 PF08238.7 ETS62292.1 - 6e-26 90.2 35.7 0.00012 22.5 0.2 10.2 10 1 0 10 10 10 7 Sel1 repeat Med5 PF08689.5 ETS62292.1 - 0.1 10.2 0.0 0.16 9.6 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 TPR_8 PF13181.1 ETS62292.1 - 4.1 7.4 0.0 4.1 7.4 0.0 3.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DRIM PF07539.7 ETS62293.1 - 4.5e-43 146.0 0.0 1.6e-42 144.2 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis PPR_3 PF13812.1 ETS62293.1 - 0.034 14.4 1.2 6.4 7.3 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Glyco_hydro_30 PF02055.11 ETS62294.1 - 5.3e-21 74.3 0.2 8.2e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 AMP-binding PF00501.23 ETS62296.1 - 9.2e-74 248.2 0.0 1.3e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS62296.1 - 4.9e-10 40.2 0.3 1.9e-09 38.3 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DnaJ_CXXCXGXG PF00684.14 ETS62298.1 - 0.04 13.9 23.6 0.019 14.9 9.7 2.6 1 1 0 2 2 2 0 DnaJ central domain Kri1 PF05178.7 ETS62299.1 - 6.2e-30 103.4 13.5 6.2e-30 103.4 9.3 4.8 6 2 0 6 6 6 1 KRI1-like family Kri1_C PF12936.2 ETS62299.1 - 6.4e-27 93.3 0.1 6.4e-27 93.3 0.1 3.9 4 0 0 4 4 4 1 KRI1-like family C-terminal Linker_histone PF00538.14 ETS62299.1 - 0.038 14.0 1.6 8.8 6.5 0.7 3.6 3 0 0 3 3 3 0 linker histone H1 and H5 family p450 PF00067.17 ETS62300.1 - 4.3e-20 71.6 0.0 1.3e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 GTP1_OBG PF01018.17 ETS62301.1 - 1.5e-39 135.1 1.8 3.2e-28 98.3 0.8 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 ETS62301.1 - 2.4e-17 62.9 0.0 5.2e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.17 ETS62301.1 - 8.2e-06 25.3 0.0 2.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FeoB_N PF02421.13 ETS62301.1 - 0.00013 21.3 0.1 0.00037 19.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B RRM_6 PF14259.1 ETS62301.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 ETS62301.1 - 0.0045 16.4 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 ETS62301.1 - 0.03 13.0 0.2 0.99 8.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein RRM_5 PF13893.1 ETS62301.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 ETS62301.1 - 0.099 12.9 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 ETS62301.1 - 0.15 11.8 0.0 8.8 6.1 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Arf PF00025.16 ETS62301.1 - 0.16 11.2 0.0 0.58 9.3 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS62301.1 - 0.37 9.8 0.0 0.69 9.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Cellulase PF00150.13 ETS62302.1 - 1.8e-10 40.5 0.2 1.8e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RCC1 PF00415.13 ETS62303.1 - 3.4e-40 136.0 5.8 1.9e-09 37.5 0.1 6.6 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS62303.1 - 2.4e-22 77.9 23.3 2.5e-07 30.1 0.8 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 ETS62303.1 - 3.8e-10 39.3 7.5 8.5e-10 38.1 5.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-UDP PF14569.1 ETS62303.1 - 0.013 15.2 2.4 0.023 14.4 1.0 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING-like PF08746.6 ETS62303.1 - 0.078 13.0 4.0 0.22 11.5 2.8 1.8 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.1 ETS62303.1 - 0.35 10.2 6.9 0.092 12.0 2.6 1.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 ETS62303.1 - 9.1 6.0 10.8 0.05 13.3 0.6 2.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 Glyco_trans_2_3 PF13632.1 ETS62304.1 - 5e-10 39.3 1.5 9.5e-10 38.5 1.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS62304.1 - 9.9e-09 35.3 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS62304.1 - 3.8e-05 23.4 0.0 7.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ETS62304.1 - 0.0011 18.2 0.1 0.0029 16.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Transp_cyt_pur PF02133.10 ETS62306.1 - 1.8e-91 306.9 35.0 2.1e-91 306.6 24.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_M28 PF04389.12 ETS62307.1 - 1.7e-28 99.6 0.0 2.7e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PrmA PF06325.8 ETS62308.1 - 2.8e-12 46.3 0.0 4.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 ETS62308.1 - 6.1e-12 45.3 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS62308.1 - 5.2e-11 43.1 0.3 3.4e-10 40.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS62308.1 - 5.6e-09 36.0 0.0 1.8e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS62308.1 - 4e-08 32.8 0.0 6.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 ETS62308.1 - 1.6e-07 30.6 0.0 2.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 ETS62308.1 - 3.1e-06 27.0 0.0 1.2e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS62308.1 - 4.1e-06 27.1 0.0 1.3e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS62308.1 - 4.3e-06 27.1 0.0 1.4e-05 25.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 ETS62308.1 - 8.1e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 ETS62308.1 - 3.4e-05 23.3 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 ETS62308.1 - 8.1e-05 23.0 0.0 0.00046 20.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 ETS62308.1 - 0.00086 19.3 0.1 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 ETS62308.1 - 0.00086 20.1 0.9 0.0051 17.6 0.0 2.7 2 1 1 3 3 2 1 Methyltransferase domain PCMT PF01135.14 ETS62308.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 ETS62308.1 - 0.0029 16.3 0.0 0.0078 14.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.10 ETS62308.1 - 0.003 16.9 0.1 0.0073 15.7 0.0 1.6 2 0 0 2 2 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 ETS62308.1 - 0.011 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 HIRA_B PF09453.5 ETS62308.1 - 0.026 14.1 0.1 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 HIRA B motif Methyltransf_32 PF13679.1 ETS62308.1 - 0.042 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pox_A_type_inc PF04508.7 ETS62308.1 - 0.075 12.8 3.4 0.21 11.4 0.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SQS_PSY PF00494.14 ETS62309.1 - 1.7e-34 119.3 0.0 2.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase SelB-wing_2 PF09106.6 ETS62309.1 - 0.046 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Prenyltrans PF00432.16 ETS62310.1 - 1.3e-34 117.3 12.2 9.1e-11 41.1 0.4 6.9 6 2 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETS62310.1 - 1e-23 83.8 0.2 3.8e-10 40.1 0.0 4.7 3 2 2 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS62310.1 - 2.3e-11 43.6 0.0 2.1e-05 24.4 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 ETS62310.1 - 0.005 16.0 0.0 0.19 10.9 0.0 3.1 1 1 4 5 5 5 1 A-macroglobulin complement component Dynein_heavy PF03028.10 ETS62312.1 - 5.5e-160 533.7 0.0 1.4e-159 532.3 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 ETS62312.1 - 8.5e-49 166.1 6.3 2e-48 164.9 4.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 ETS62312.1 - 2.1e-44 151.1 0.0 4.6e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 Sipho_Gp157 PF05565.6 ETS62312.1 - 0.006 16.1 1.4 0.006 16.1 1.0 3.7 3 0 0 3 3 3 2 Siphovirus Gp157 DUF4250 PF14056.1 ETS62312.1 - 0.081 12.6 0.6 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Mod_r PF07200.8 ETS62312.1 - 0.18 11.7 16.8 0.47 10.3 0.7 3.4 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 ETS62312.1 - 1.2 8.2 22.0 0.35 10.0 0.9 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding eIF2A PF08662.6 ETS62313.1 - 3.3e-82 274.9 0.1 6.9e-81 270.6 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDV3 PF15359.1 ETS62313.1 - 0.21 11.6 11.2 0.05 13.6 1.2 3.2 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 WD40 PF00400.27 ETS62313.1 - 0.32 10.9 3.2 5.2 7.1 0.0 4.3 6 0 0 6 6 6 0 WD domain, G-beta repeat TauD PF02668.11 ETS62314.1 - 7.2e-29 101.2 0.3 9.2e-29 100.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidohydro_2 PF04909.9 ETS62315.1 - 4.6e-30 105.1 1.6 1e-29 103.9 1.1 1.6 1 1 0 1 1 1 1 Amidohydrolase APG9 PF04109.11 ETS62316.1 - 3e-160 533.1 0.1 3.9e-160 532.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DIOX_N PF14226.1 ETS62316.1 - 1.1e-24 87.1 0.1 2.5e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS62316.1 - 1.1e-18 67.3 0.0 4e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2231 PF09990.4 ETS62316.1 - 0.0089 16.3 1.0 0.0089 16.3 0.7 2.6 2 1 0 2 2 2 1 Predicted membrane protein (DUF2231) CPSase_L_D2 PF02786.12 ETS62317.1 - 1.3e-74 249.9 0.0 2.2e-74 249.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ETS62317.1 - 2.7e-41 140.1 1.3 3.9e-41 139.5 0.1 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS62317.1 - 3.1e-34 117.1 0.0 4.6e-33 113.4 0.0 2.4 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 ETS62317.1 - 4.4e-15 55.8 0.1 1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS62317.1 - 1.2e-11 44.0 0.0 2.5e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 ETS62317.1 - 2.2e-11 43.2 0.1 4.8e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 ETS62317.1 - 5.6e-10 38.9 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 ETS62317.1 - 2.8e-07 30.0 0.0 9.7e-07 28.3 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 ETS62317.1 - 0.00027 20.8 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 ETS62317.1 - 0.00052 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Cro PF09048.5 ETS62317.1 - 0.024 14.2 0.0 0.1 12.2 0.0 2.1 1 0 0 1 1 1 0 Cro EMP24_GP25L PF01105.19 ETS62318.1 - 1.2e-43 148.9 0.0 1.4e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NuA4 PF09340.5 ETS62319.1 - 4.9e-23 80.5 0.1 4.9e-23 80.5 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF3185 PF11381.3 ETS62321.1 - 0.094 12.4 0.1 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Cyt_c_ox_IV PF12270.3 ETS62322.1 - 0.56 9.9 3.1 0.34 10.6 0.4 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV ER_lumen_recept PF00810.13 ETS62323.1 - 2.3e-57 193.6 7.3 2.9e-57 193.3 5.1 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 ETS62323.1 - 4.9e-05 22.7 4.5 0.44 10.1 0.0 3.9 3 1 1 4 4 4 2 PQ loop repeat RRM_1 PF00076.17 ETS62324.1 - 2.6e-06 26.9 0.1 6.5e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS62324.1 - 3.1e-05 23.8 0.0 7.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS62324.1 - 0.00029 20.6 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 ETS62325.1 - 1.6e-15 56.9 0.2 9.7e-15 54.4 0.0 2.5 2 0 0 2 2 2 1 FHA domain Lipoprotein_7 PF01540.11 ETS62325.1 - 0.00046 19.3 0.8 0.086 11.8 0.1 2.1 2 0 0 2 2 2 2 Adhesin lipoprotein DUF812 PF05667.6 ETS62325.1 - 0.017 13.6 27.0 0.19 10.1 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF1664 PF07889.7 ETS62325.1 - 0.2 11.4 11.9 0.51 10.1 1.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tweety PF04906.8 ETS62325.1 - 0.5 8.7 6.8 0.33 9.3 0.4 2.2 2 0 0 2 2 2 0 Tweety Mnd1 PF03962.10 ETS62325.1 - 0.54 9.8 24.1 0.039 13.6 1.2 3.1 2 1 1 3 3 3 0 Mnd1 family Spt20 PF12090.3 ETS62325.1 - 1.3 8.3 9.5 0.023 14.0 1.3 1.8 2 0 0 2 2 2 0 Spt20 family DUF2721 PF11026.3 ETS62325.1 - 4.2 7.0 5.7 8.6 6.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) BRO1 PF03097.13 ETS62328.1 - 2e-13 49.8 0.0 2.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain IncA PF04156.9 ETS62329.1 - 0.00043 19.9 9.9 0.00043 19.9 6.9 8.4 4 2 2 6 6 6 3 IncA protein HAD PF12710.2 ETS62330.1 - 1.3e-17 64.6 0.0 5.4e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETS62330.1 - 1.5e-16 60.1 0.0 2.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETS62330.1 - 2.2e-14 54.4 1.0 6.8e-13 49.5 0.7 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS62330.1 - 9.2e-14 51.1 0.0 2.3e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS62330.1 - 0.0028 17.2 0.2 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS62330.1 - 0.071 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Neurokinin_B PF03823.9 ETS62330.1 - 0.077 12.7 0.5 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 Neurokinin B Cut12 PF11500.3 ETS62330.1 - 2.4 7.8 5.8 31 4.2 0.0 3.0 3 0 0 3 3 3 0 Spindle pole body formation-associated protein Pinin_SDK_memA PF04696.8 ETS62331.1 - 7.8e-10 38.4 9.9 7.4e-09 35.2 6.9 2.1 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region vWA-TerF-like PF10138.4 ETS62332.1 - 1.4e-08 34.8 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 ETS62332.1 - 5.6e-05 22.9 0.0 0.00056 19.6 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETS62332.1 - 0.00086 19.4 1.1 0.002 18.2 0.7 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain PAT1 PF09770.4 ETS62332.1 - 7.5 4.6 10.4 12 3.9 7.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HEAT_EZ PF13513.1 ETS62333.1 - 3.5e-26 90.9 22.4 4.1e-10 39.8 0.0 10.7 9 3 4 13 13 11 6 HEAT-like repeat HEAT PF02985.17 ETS62333.1 - 2.2e-22 77.0 13.7 0.0016 18.3 0.0 10.3 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 ETS62333.1 - 2.4e-19 69.4 3.7 1.5e-05 25.2 0.0 7.5 4 4 6 10 10 10 5 HEAT repeats Vac14_Fab1_bd PF12755.2 ETS62333.1 - 3.8e-11 43.2 0.0 0.00019 21.7 0.2 4.2 2 2 2 4 4 4 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 ETS62333.1 - 4.2e-07 29.7 0.1 2.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.2 ETS62333.1 - 3.5e-05 23.7 1.7 0.056 13.2 0.1 4.9 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 ETS62333.1 - 3.5e-05 23.4 2.9 1.3 8.9 0.0 6.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 ETS62333.1 - 0.0004 19.2 0.3 1 8.0 0.0 3.5 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 ETS62333.1 - 0.00042 19.7 0.2 9.9 5.4 0.1 5.2 4 2 2 6 6 6 0 CLASP N terminal Proteasom_PSMB PF10508.4 ETS62333.1 - 0.0053 15.0 0.0 0.025 12.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Cnd3 PF12719.2 ETS62333.1 - 0.0062 15.5 0.2 1.2 8.0 0.1 3.2 2 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Ecm29 PF13001.2 ETS62333.1 - 0.024 13.1 0.0 11 4.3 0.0 3.8 4 0 0 4 4 4 0 Proteasome stabiliser UNC45-central PF11701.3 ETS62333.1 - 0.046 13.3 0.1 0.42 10.2 0.0 2.6 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Homeobox PF00046.24 ETS62333.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox domain CENP-B_dimeris PF09026.5 ETS62333.1 - 0.43 10.8 7.4 1.2 9.4 5.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 ETS62333.1 - 5.6 6.4 7.2 10 5.5 5.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Peptidase_S8 PF00082.17 ETS62334.1 - 2.4e-48 164.7 8.9 3.4e-48 164.2 5.9 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 ETS62334.1 - 2.6e-11 43.9 0.0 5.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cpn60_TCP1 PF00118.19 ETS62335.1 - 8.5e-139 463.2 0.1 9.7e-139 463.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GIDA PF01134.17 ETS62336.1 - 7.3e-131 436.6 0.0 1.2e-130 435.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 ETS62336.1 - 6.1e-13 48.6 0.0 1.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 ETS62336.1 - 3.6e-08 33.5 0.1 9.8e-08 32.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS62336.1 - 2.5e-06 26.8 0.7 4.2e-06 26.1 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS62336.1 - 0.00021 20.2 2.0 0.00061 18.7 1.4 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 ETS62336.1 - 0.00083 18.3 8.4 0.0043 16.0 0.3 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS62336.1 - 0.0032 15.9 2.2 0.066 11.6 0.5 2.7 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 ETS62336.1 - 0.018 14.1 0.3 0.032 13.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 ETS62336.1 - 0.027 14.5 0.2 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS62336.1 - 0.043 12.7 0.6 0.94 8.3 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 ETS62336.1 - 0.25 11.7 0.8 0.61 10.5 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PH PF00169.24 ETS62337.1 - 9.6e-07 28.9 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PH domain SLD3 PF08639.5 ETS62338.1 - 8.4e-08 31.2 0.1 1.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 Glyco_hydro_31 PF01055.21 ETS62339.1 - 1.6e-132 442.4 1.2 2.7e-132 441.7 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS62339.1 - 6.2e-20 70.8 0.0 2.4e-19 68.9 0.0 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like TP_methylase PF00590.15 ETS62340.1 - 1.3e-16 60.9 0.0 3.5e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2335 PF10097.4 ETS62340.1 - 0.024 14.2 0.8 0.065 12.8 0.5 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Sad1_UNC PF07738.8 ETS62341.1 - 1.7e-27 95.8 0.0 2.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Epiglycanin_C PF14654.1 ETS62341.1 - 0.0041 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region MFS_1 PF07690.11 ETS62343.1 - 5.2e-13 48.4 50.5 7e-11 41.4 34.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Myb_Cef PF11831.3 ETS62344.1 - 2.1e-55 187.4 3.3 2.1e-55 187.4 2.3 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 ETS62344.1 - 3.5e-22 78.1 5.3 2.2e-10 40.4 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS62344.1 - 1e-18 67.1 8.2 3.4e-13 49.4 2.2 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain HCV_NS4b PF01001.14 ETS62344.1 - 0.06 12.7 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b bZIP_1 PF00170.16 ETS62345.1 - 1.3e-05 25.0 1.6 4.4e-05 23.3 1.1 1.9 1 0 0 1 1 1 1 bZIP transcription factor CRF1 PF10380.4 ETS62345.1 - 0.0031 17.8 0.8 0.01 16.1 0.6 1.9 1 0 0 1 1 1 1 Transcription factor CRF1 bZIP_2 PF07716.10 ETS62345.1 - 1.4 8.7 9.4 0.11 12.3 2.7 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Uso1_p115_head PF04869.9 ETS62346.1 - 2.3e-56 190.8 0.0 3.7e-53 180.3 0.0 2.8 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 ETS62346.1 - 0.00011 22.1 30.0 0.00011 22.1 20.8 7.5 3 1 6 9 9 9 1 Uso1 / p115 like vesicle tethering protein, C terminal region Reo_sigmaC PF04582.7 ETS62346.1 - 0.036 13.2 33.6 0.12 11.4 4.7 3.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Spo12 PF05032.7 ETS62347.1 - 0.00025 20.5 0.4 0.00056 19.4 0.3 1.6 1 0 0 1 1 1 1 Spo12 family 3-PAP PF12578.3 ETS62347.1 - 0.14 12.0 0.6 0.3 10.9 0.2 1.8 2 0 0 2 2 2 0 Myotubularin-associated protein EcKinase PF02958.15 ETS62348.1 - 1.5e-27 96.4 0.0 9e-27 93.9 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 ETS62348.1 - 2e-12 47.3 2.7 3.3e-12 46.6 1.8 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 ETS62348.1 - 2.4e-08 33.0 0.0 3.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) SSrecog PF03531.9 ETS62349.1 - 1.8e-75 253.0 0.3 8.7e-75 250.8 0.2 1.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 ETS62349.1 - 9.6e-25 86.4 0.0 2.8e-24 84.9 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 ETS62349.1 - 0.81 7.6 6.6 1.3 6.9 4.6 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF1900 PF08954.6 ETS62350.1 - 2.4e-45 153.3 0.0 3.9e-44 149.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 ETS62350.1 - 1.7e-31 107.6 0.3 3.5e-31 106.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 ETS62350.1 - 1.9e-17 62.3 3.6 5.4e-08 32.4 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PspA_IM30 PF04012.7 ETS62350.1 - 0.0005 19.5 0.8 0.00084 18.7 0.6 1.3 1 0 0 1 1 1 1 PspA/IM30 family NTR2 PF15458.1 ETS62350.1 - 0.034 13.3 0.7 0.062 12.5 0.5 1.4 1 0 0 1 1 1 0 Nineteen complex-related protein 2 CRAL_TRIO PF00650.15 ETS62351.1 - 3.8e-30 104.4 0.0 6.7e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 ETS62351.1 - 2.8e-09 37.0 0.0 5.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS62351.1 - 7.1e-09 35.6 0.2 2.1e-08 34.1 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF2360 PF10152.4 ETS62351.1 - 3.5 7.8 12.6 2.7 8.2 5.3 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Zn_clus PF00172.13 ETS62352.1 - 6.3e-08 32.4 7.3 1.1e-07 31.6 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase PF05875.7 ETS62353.1 - 8.8e-80 267.6 8.0 1.1e-79 267.3 5.5 1.0 1 0 0 1 1 1 1 Ceramidase Glyco_hydro_10 PF00331.15 ETS62354.1 - 1.5e-50 172.1 0.0 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4120 PF13496.1 ETS62354.1 - 0.16 11.9 0.4 8.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) TrkH PF02386.11 ETS62355.1 - 2.6e-84 282.8 16.3 2.2e-83 279.7 2.9 2.1 2 0 0 2 2 2 2 Cation transport protein UPF0016 PF01169.14 ETS62356.1 - 1.6e-42 143.5 25.1 2.2e-21 75.7 5.8 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 ETS62356.1 - 0.03 13.7 0.2 0.03 13.7 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein TerC family Saccharop_dh PF03435.13 ETS62357.1 - 2.5e-21 76.0 0.1 4.1e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 ETS62357.1 - 7.2e-05 22.7 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 ETS62357.1 - 0.0023 18.2 0.0 0.0069 16.6 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS62357.1 - 0.0044 17.1 0.0 0.0097 16.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 ETS62357.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 ETS62357.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Frataxin_Cyay PF01491.11 ETS62359.1 - 3.8e-36 123.2 0.0 5.2e-36 122.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Aminotran_1_2 PF00155.16 ETS62360.1 - 6.6e-58 196.3 0.0 9.2e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase PF00756.15 ETS62360.1 - 2.2e-48 164.8 0.0 3e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 ETS62360.1 - 4.6e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS62360.1 - 0.011 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 ETS62360.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETS62360.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 ETS62360.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold MIF4G PF02854.14 ETS62362.1 - 8.7e-58 195.1 0.7 1.3e-57 194.6 0.5 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 ETS62362.1 - 1.4e-20 72.9 1.1 3e-20 71.8 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 ETS62362.1 - 5.3e-09 35.7 0.2 1.6e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 MA3 domain Hydrophobin PF01185.13 ETS62364.1 - 2.3e-16 60.0 11.6 2.3e-16 60.0 8.0 2.3 2 1 0 2 2 2 1 Fungal hydrophobin Cu_amine_oxidN1 PF07833.6 ETS62364.1 - 0.097 13.0 1.4 0.2 12.0 0.5 1.9 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain Gly_acyl_tr_N PF06021.6 ETS62364.1 - 4.1 6.7 6.7 1.7 8.0 0.2 3.0 1 1 4 5 5 5 0 Aralkyl acyl-CoA:amino acid N-acyltransferase HSP70 PF00012.15 ETS62365.1 - 5.5e-124 414.3 0.9 1.7e-67 227.7 0.8 2.0 1 1 1 2 2 2 2 Hsp70 protein Ribosomal_S2 PF00318.15 ETS62366.1 - 8e-47 159.1 0.0 1.3e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S2 ABC_membrane PF00664.18 ETS62367.1 - 3.6e-70 236.4 17.7 5.3e-42 144.1 1.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS62367.1 - 5.8e-60 201.5 0.0 3e-29 102.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 ETS62367.1 - 2.6e-14 53.0 0.1 0.00014 21.1 0.2 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS62367.1 - 2e-10 40.9 8.6 4.6e-06 26.7 0.4 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_10 PF12846.2 ETS62367.1 - 8.1e-10 38.6 0.4 0.051 12.9 0.0 4.3 4 0 0 4 4 4 2 AAA-like domain AAA_21 PF13304.1 ETS62367.1 - 9.8e-10 38.8 0.0 0.012 15.6 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_22 PF13401.1 ETS62367.1 - 3.6e-09 36.8 0.3 0.045 13.8 0.0 4.8 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 ETS62367.1 - 5.3e-08 33.7 0.0 0.0027 18.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS62367.1 - 3.4e-07 29.6 0.0 0.019 14.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 ETS62367.1 - 5.7e-07 28.4 0.1 0.0094 14.5 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF87 PF01935.12 ETS62367.1 - 3.2e-06 27.1 0.3 0.054 13.3 0.0 3.4 4 0 0 4 4 3 2 Domain of unknown function DUF87 AAA_18 PF13238.1 ETS62367.1 - 2.4e-05 24.6 0.0 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 ETS62367.1 - 5.4e-05 23.0 0.4 0.37 10.7 0.1 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 ETS62367.1 - 6e-05 22.2 0.1 0.27 10.4 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETS62367.1 - 0.00011 21.6 0.4 0.47 9.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 ETS62367.1 - 0.00013 21.9 0.1 0.42 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 ETS62367.1 - 0.00019 21.1 0.2 1 9.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 ETS62367.1 - 0.00067 18.7 0.0 0.35 9.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 ETS62367.1 - 0.0016 18.4 0.0 1.9 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETS62367.1 - 0.0025 17.9 0.0 3.2 7.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase PRK PF00485.13 ETS62367.1 - 0.0033 17.0 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 ETS62367.1 - 0.0034 17.5 0.0 41 4.3 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 ETS62367.1 - 0.0074 15.9 0.0 4.4 7.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 ETS62367.1 - 0.011 15.4 0.0 6.4 6.4 0.0 3.0 3 0 0 3 3 2 0 NACHT domain KaiC PF06745.8 ETS62367.1 - 0.012 14.7 2.4 18 4.3 0.0 3.4 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.16 ETS62367.1 - 0.021 14.0 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 ETS62367.1 - 0.025 14.2 0.2 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Miro PF08477.8 ETS62367.1 - 0.034 14.6 0.1 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein tRNA_lig_kinase PF08303.6 ETS62367.1 - 0.036 13.9 0.0 0.9 9.3 0.0 2.4 2 0 0 2 2 2 0 tRNA ligase kinase domain G-alpha PF00503.15 ETS62367.1 - 0.082 11.5 0.0 5.8 5.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 ETS62367.1 - 0.17 11.8 0.0 27 4.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETS62367.1 - 0.22 11.3 0.4 14 5.4 0.1 2.9 3 0 0 3 3 2 0 Dynamin family AAA_23 PF13476.1 ETS62367.1 - 0.44 10.8 0.1 12 6.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain Cyclin PF08613.6 ETS62369.1 - 4.8e-10 40.0 0.1 1.4e-09 38.5 0.1 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 ETS62369.1 - 9.5e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.20 ETS62372.1 - 1.9e-22 79.9 0.2 3.6e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS62372.1 - 2.2e-09 37.4 0.1 3.5e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS62372.1 - 2.7e-07 30.4 0.5 5.4e-07 29.4 0.1 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 ETS62372.1 - 0.00013 22.0 0.1 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS62372.1 - 0.017 14.0 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS62372.1 - 0.065 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA-synt_2 PF00152.15 ETS62373.1 - 7.4e-71 238.6 0.0 9.7e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS62373.1 - 1.1e-11 44.3 0.0 2.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HEAT_2 PF13646.1 ETS62374.1 - 1.5e-38 130.9 52.8 1.2e-09 38.2 0.0 16.1 9 4 6 16 16 16 9 HEAT repeats DUF3554 PF12074.3 ETS62374.1 - 1.4e-37 129.8 4.5 2.9e-35 122.2 1.8 5.0 5 1 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT PF02985.17 ETS62374.1 - 4.3e-32 107.2 30.7 0.097 12.8 0.0 20.3 23 0 0 23 23 21 9 HEAT repeat HEAT_EZ PF13513.1 ETS62374.1 - 9.2e-21 73.7 66.3 0.0001 22.6 0.0 20.2 19 3 2 21 21 18 8 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETS62374.1 - 7.5e-09 35.8 0.0 1.5 9.2 0.0 8.5 8 2 2 10 10 8 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 ETS62374.1 - 2.6e-07 30.4 3.2 0.071 12.7 0.0 6.4 5 0 0 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 ETS62374.1 - 3.3e-06 25.7 6.6 0.025 12.9 0.0 6.4 6 2 1 7 7 7 2 Adaptin N terminal region Cnd1 PF12717.2 ETS62374.1 - 1.2e-05 25.2 0.0 21 4.9 0.0 8.0 7 1 2 10 10 9 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 ETS62374.1 - 7.5e-05 22.5 1.6 1.1 9.2 0.1 4.6 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 ETS62374.1 - 0.00034 19.6 0.1 0.42 9.5 0.0 4.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 ETS62374.1 - 0.0004 20.1 15.9 31 4.5 0.0 10.2 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 ETS62374.1 - 0.038 13.9 0.1 55 3.7 0.0 4.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Membr_traf_MHD PF10540.4 ETS62374.1 - 0.11 12.2 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain Pox_RNA_Pol_19 PF05320.7 ETS62374.1 - 1.1 8.9 4.3 0.94 9.2 1.7 1.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mito_carr PF00153.22 ETS62375.1 - 1.7e-47 159.0 0.1 8.3e-15 54.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 ETS62375.1 - 0.06 13.2 0.0 8.9 6.3 0.0 2.7 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Anoctamin PF04547.7 ETS62376.1 - 1.3e-110 370.1 0.0 1.7e-110 369.8 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel LSM PF01423.17 ETS62377.1 - 7.2e-12 44.6 0.1 1.5e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 LSM domain GRP PF07172.6 ETS62377.1 - 2.3 8.7 15.3 3.8 8.0 10.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family Trypan_PARP PF05887.6 ETS62378.1 - 0.0099 15.6 1.7 0.015 15.0 1.2 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) EF-hand_6 PF13405.1 ETS62380.1 - 5.3e-11 41.4 1.9 6e-05 22.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETS62380.1 - 1.4e-10 41.1 0.2 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETS62380.1 - 5.9e-09 34.5 4.1 4.9e-05 22.3 0.2 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 ETS62380.1 - 9e-06 24.8 1.0 0.016 14.5 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETS62380.1 - 0.00031 20.3 1.2 0.66 9.6 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair NAPRTase PF04095.11 ETS62382.1 - 8.7e-53 179.1 0.0 1.2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family FCD PF07729.7 ETS62382.1 - 0.039 14.2 1.3 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 FCD domain Glyco_transf_90 PF05686.7 ETS62383.1 - 1.1e-26 93.4 1.8 1.1e-23 83.5 0.5 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 FAP PF07174.6 ETS62383.1 - 0.025 13.8 8.3 0.04 13.2 5.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) UBA_4 PF14555.1 ETS62383.1 - 0.055 13.0 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Y_phosphatase PF00102.22 ETS62384.1 - 1.7e-52 178.1 0.0 7.6e-46 156.3 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 ETS62384.1 - 0.0016 18.7 0.0 0.029 14.7 0.0 2.7 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 ETS62384.1 - 0.029 14.6 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 ETS62384.1 - 0.16 12.0 0.1 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPc PF00782.15 ETS62384.1 - 0.39 10.3 0.7 0.78 9.3 0.5 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cwf_Cwc_15 PF04889.7 ETS62385.1 - 3.4e-58 197.2 15.6 4.1e-58 196.9 10.8 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 ETS62385.1 - 0.05 12.8 18.9 0.061 12.6 13.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETS62385.1 - 0.65 7.8 20.1 0.79 7.5 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETS62385.1 - 0.71 8.2 19.7 0.81 8.0 13.7 1.1 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 ETS62385.1 - 1.3 8.7 7.7 1.7 8.4 5.4 1.4 1 0 0 1 1 1 0 DDHD domain Cytomega_UL84 PF06284.6 ETS62385.1 - 1.6 7.0 8.7 2.1 6.6 6.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SAPS PF04499.10 ETS62385.1 - 4.2 5.8 7.9 4.3 5.8 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 ETS62385.1 - 5.3 4.7 9.4 6.3 4.5 6.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ycf1 PF05758.7 ETS62385.1 - 6.7 4.2 7.2 6.8 4.2 5.0 1.1 1 0 0 1 1 1 0 Ycf1 HNF-1_N PF04814.8 ETS62385.1 - 8 6.5 14.8 18 5.3 9.9 1.7 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RR_TM4-6 PF06459.7 ETS62385.1 - 8.4 6.2 14.5 11 5.8 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 ETS62385.1 - 8.6 4.2 18.4 11 3.8 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein FKBP_C PF00254.23 ETS62386.1 - 2.9e-35 120.1 0.0 3.6e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.20 ETS62387.1 - 1.6e-67 227.3 0.0 2e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62387.1 - 4.3e-36 124.3 0.0 5.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS62387.1 - 0.00049 19.1 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS62387.1 - 0.014 14.5 0.0 0.034 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS62387.1 - 0.06 13.0 0.4 0.27 10.9 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETS62387.1 - 0.15 11.4 0.1 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL LZ_Tnp_IS66 PF13007.2 ETS62387.1 - 0.63 10.7 3.9 1.6 9.4 2.7 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain UPF0220 PF05255.6 ETS62388.1 - 3.8e-58 195.4 0.0 4.8e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ApbA_C PF08546.6 ETS62389.1 - 1.3e-25 89.7 0.0 2.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 ETS62389.1 - 5.3e-20 71.3 0.0 8.4e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 ETS62389.1 - 0.014 14.2 0.8 0.052 12.4 0.6 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.16 ETS62389.1 - 0.022 14.5 0.3 0.041 13.7 0.2 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 ETS62389.1 - 0.036 14.4 0.2 0.08 13.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase polyprenyl_synt PF00348.12 ETS62390.1 - 1.3e-45 155.3 0.0 1.2e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase RNA_pol_Rpb8 PF03870.10 ETS62391.1 - 1.2e-36 125.8 0.4 8.3e-36 123.2 0.3 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb8 DUF1193 PF06702.7 ETS62392.1 - 0.033 13.5 0.2 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1193) Med17 PF10156.4 ETS62392.1 - 0.049 11.8 1.1 0.065 11.4 0.2 1.5 2 0 0 2 2 2 0 Subunit 17 of Mediator complex Lectin_leg-like PF03388.8 ETS62393.1 - 5.6e-63 212.1 0.1 1.2e-62 211.0 0.0 1.4 2 0 0 2 2 2 1 Legume-like lectin family Lectin_legB PF00139.14 ETS62393.1 - 0.017 14.5 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Legume lectin domain DUF4349 PF14257.1 ETS62393.1 - 0.33 10.1 0.9 0.52 9.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) FAD_binding_4 PF01565.18 ETS62394.1 - 6.6e-12 45.0 0.5 4.6e-05 22.9 0.1 3.0 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 ETS62394.1 - 2.5e-07 30.4 0.1 8.1e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Bromodomain PF00439.20 ETS62395.1 - 2.8e-21 75.2 0.2 5.3e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 ETS62395.1 - 6e-05 22.6 0.0 0.00051 19.7 0.0 2.3 2 0 0 2 2 2 1 Bromodomain associated adh_short PF00106.20 ETS62396.1 - 1e-10 41.7 0.8 1.4e-07 31.5 0.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETS62396.1 - 2.4e-10 40.6 0.0 3.8e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS62396.1 - 0.00031 20.4 0.1 0.00072 19.2 0.1 1.6 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETS62396.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyridox_oxidase PF01243.15 ETS62397.1 - 1.1e-10 41.4 0.0 1.2e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GIT_SHD PF08518.6 ETS62398.1 - 8.5e-27 92.1 7.7 6.6e-16 57.3 0.6 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Myosin_tail_1 PF01576.14 ETS62398.1 - 0.0015 16.4 23.6 0.0015 16.4 16.3 2.3 2 0 0 2 2 2 1 Myosin tail GAS PF13851.1 ETS62398.1 - 0.098 11.8 21.0 0.2 10.8 2.3 2.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 ETS62398.1 - 0.35 10.4 17.2 1 8.8 1.2 3.0 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 ETS62398.1 - 0.93 9.7 12.0 0.099 12.9 0.4 4.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 ETS62398.1 - 1 9.2 19.0 2.5 7.9 1.7 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 ETS62398.1 - 1.4 9.2 21.1 0.5 10.7 3.8 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 ETS62398.1 - 2.7 7.7 24.6 5.2 6.8 6.9 3.9 4 2 0 4 4 4 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.1 ETS62398.1 - 6.8 6.7 19.7 1.9 8.5 0.3 4.4 3 1 1 4 4 4 0 Syntaxin-like protein zf-C2H2 PF00096.21 ETS62399.1 - 9.5e-06 25.6 2.6 0.012 15.8 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS62399.1 - 0.023 15.0 6.9 0.037 14.3 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 ETS62399.1 - 0.038 14.1 1.1 4.9 7.5 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Alpha-amylase_C PF02806.13 ETS62400.1 - 8.1e-25 86.7 0.1 8.2e-24 83.5 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 ETS62400.1 - 4.1e-17 62.5 0.0 5.7e-14 52.2 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 ETS62400.1 - 1.5e-14 53.7 0.0 5e-14 52.1 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 ETS62400.1 - 0.014 14.2 0.0 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme G-patch PF01585.18 ETS62401.1 - 7.1e-09 35.3 1.3 2e-08 33.8 0.9 1.8 1 0 0 1 1 1 1 G-patch domain SprA-related PF12118.3 ETS62401.1 - 2.1e-05 23.9 37.9 0.0009 18.6 10.2 2.1 2 0 0 2 2 2 2 SprA-related family G-patch_2 PF12656.2 ETS62401.1 - 0.0058 16.4 0.9 0.0058 16.4 0.6 4.8 3 2 0 3 3 3 1 DExH-box splicing factor binding site YL1 PF05764.8 ETS62401.1 - 0.22 11.0 55.4 0.12 11.9 18.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF1510 PF07423.6 ETS62401.1 - 0.26 10.6 57.0 0.14 11.4 10.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SR-25 PF10500.4 ETS62401.1 - 0.53 9.7 84.1 0.019 14.4 13.4 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.8 ETS62401.1 - 0.94 8.6 44.2 0.095 11.8 12.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 ETS62401.1 - 0.99 7.7 68.2 0.5 8.7 25.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF966 PF06136.8 ETS62401.1 - 4.3 6.6 36.4 4.3 6.6 12.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) WD40 PF00400.27 ETS62402.1 - 7.4e-14 51.0 22.3 5.2e-07 29.3 0.1 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 ETS62402.1 - 0.00021 21.1 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain G-alpha PF00503.15 ETS62403.1 - 2.5e-127 424.7 0.0 3.2e-127 424.4 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS62403.1 - 1.8e-14 53.3 0.1 1.9e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS62403.1 - 0.00072 18.7 0.2 0.77 8.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS62403.1 - 0.0093 16.4 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein PNRC PF15365.1 ETS62403.1 - 0.033 14.1 0.2 0.033 14.1 0.1 2.9 3 1 0 3 3 3 0 Proline-rich nuclear receptor coactivator AAA_29 PF13555.1 ETS62403.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mito_carr PF00153.22 ETS62405.1 - 5.6e-59 195.8 3.5 7.3e-21 73.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RhoGEF PF00621.15 ETS62406.1 - 1e-33 116.7 0.0 7.4e-30 104.1 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain BAR PF03114.13 ETS62406.1 - 8.7e-11 41.7 1.8 9.3e-11 41.6 0.3 1.7 2 0 0 2 2 2 1 BAR domain Sugar_tr PF00083.19 ETS62407.1 - 3e-103 345.8 23.8 3.6e-103 345.5 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS62407.1 - 8.9e-32 110.1 33.5 1.3e-30 106.3 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS62407.1 - 4e-07 28.6 7.3 7.3e-07 27.7 2.0 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 ETS62408.1 - 7e-79 265.1 0.0 9e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS62408.1 - 9.3e-13 48.9 0.1 2.2e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_T4_Ndd PF06591.6 ETS62408.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) ADH_N PF08240.7 ETS62409.1 - 2e-29 101.5 2.9 3.7e-29 100.6 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS62409.1 - 4.1e-14 52.2 0.0 6.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 ETS62409.1 - 0.026 14.1 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.1 ETS62409.1 - 0.066 14.1 0.0 0.16 12.8 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS62409.1 - 0.15 11.2 0.1 0.33 10.0 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.7 ETS62410.1 - 1.6e-23 82.5 2.0 2.7e-23 81.7 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS62410.1 - 2.9e-16 59.2 0.0 5.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 ETS62410.1 - 0.0027 18.2 0.0 0.0064 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 ETS62410.1 - 0.0048 16.0 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDZ_2 PF13180.1 ETS62410.1 - 0.051 13.4 1.2 0.4 10.6 0.1 2.9 3 1 1 4 4 4 0 PDZ domain Methyltransf_31 PF13847.1 ETS62410.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain XdhC_C PF13478.1 ETS62410.1 - 0.071 13.4 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain ADH_zinc_N_2 PF13602.1 ETS62410.1 - 0.12 13.2 0.0 0.31 11.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 ETS62410.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 ETS62411.1 - 5.2e-26 91.9 0.5 1.1e-25 90.8 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS62411.1 - 9.9e-05 21.8 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 ETS62411.1 - 0.00027 20.5 0.0 0.006 16.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS62411.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Far-17a_AIG1 PF04750.9 ETS62412.1 - 4.1e-49 166.4 1.7 4.7e-49 166.2 1.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Sulfatase PF00884.18 ETS62413.1 - 6e-56 189.8 0.0 8.1e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 ETS62413.1 - 3.5e-23 81.1 1.4 7.5e-23 80.1 1.0 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 ETS62413.1 - 5.1e-09 35.9 0.0 6.4e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 ETS62413.1 - 0.0044 17.3 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 ETS62413.1 - 0.0066 14.9 0.0 0.01 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) TatD_DNase PF01026.16 ETS62414.1 - 1e-35 123.2 0.0 1.3e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Sulfatase PF00884.18 ETS62415.1 - 1.1e-49 169.3 0.4 1.4e-49 168.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS62415.1 - 0.0014 18.0 0.1 0.0035 16.7 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Transferase PF02458.10 ETS62416.1 - 2.3e-20 72.4 0.0 3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family NmrA PF05368.8 ETS62417.1 - 2.9e-15 56.1 0.0 4.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS62417.1 - 1.4e-14 54.4 0.0 2.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS62417.1 - 0.00097 18.6 0.0 0.0074 15.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 ETS62417.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMN_red PF03358.10 ETS62418.1 - 7.8e-24 83.9 0.0 1.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ETS62418.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold adh_short PF00106.20 ETS62419.1 - 2.4e-26 92.6 0.2 4.1e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS62419.1 - 5.8e-12 45.6 1.8 2.6e-11 43.5 1.2 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS62419.1 - 2.6e-06 27.4 0.4 3.4e-06 27.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS62419.1 - 0.0038 17.2 0.2 0.014 15.4 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS62419.1 - 0.0054 15.6 0.1 0.0073 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NicO PF03824.11 ETS62420.1 - 2.8e-35 122.0 5.4 8.6e-34 117.1 1.2 3.2 2 1 0 2 2 2 1 High-affinity nickel-transport protein Abhydrolase_3 PF07859.8 ETS62420.1 - 4.4e-21 75.4 0.1 2.4e-19 69.7 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold 4HBT_2 PF13279.1 ETS62420.1 - 9.7e-06 26.0 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily Abhydrolase_5 PF12695.2 ETS62420.1 - 0.004 16.9 0.0 0.0097 15.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hemerythrin PF01814.18 ETS62423.1 - 3.8e-10 40.0 7.2 3.8e-10 40.0 5.0 1.8 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Tht1 PF04163.7 ETS62423.1 - 0.66 8.3 3.1 0.75 8.1 2.1 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Fungal_trans PF04082.13 ETS62424.1 - 3.6e-27 94.8 0.2 6e-27 94.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS62424.1 - 1.4e-07 31.2 11.1 2.8e-07 30.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS62425.1 - 6.3e-71 239.2 0.0 7.6e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 ETS62425.1 - 3.7e-48 163.8 0.0 6.6e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 ETS62425.1 - 1.4e-24 86.1 0.0 4.2e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal PGAP1 PF07819.8 ETS62426.1 - 0.023 14.2 0.0 0.046 13.3 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Cyclin PF08613.6 ETS62427.1 - 9.7e-31 107.1 0.0 1.9e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 ETS62427.1 - 0.0002 20.9 0.1 0.00029 20.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Med24_N PF11277.3 ETS62427.1 - 0.13 9.7 1.0 0.17 9.3 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF2057 PF09829.4 ETS62427.1 - 7 6.2 8.4 6.3 6.4 2.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF59 PF01883.14 ETS62428.1 - 4.8e-09 36.0 0.0 9.8e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 FBA_2 PF07735.12 ETS62428.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 F-box associated Med19 PF10278.4 ETS62429.1 - 0.025 14.2 0.3 0.048 13.3 0.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3722 PF12519.3 ETS62430.1 - 1.9e-93 312.4 1.5 5.3e-93 310.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 ETS62430.1 - 0.01 15.1 0.0 0.088 12.0 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic porin 4HBT_3 PF13622.1 ETS62431.1 - 2.1e-35 122.7 0.3 2.4e-35 122.5 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily NTF2 PF02136.15 ETS62432.1 - 1.8e-26 92.8 0.5 4.9e-26 91.4 0.3 1.8 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 ETS62432.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS62432.1 - 8.2e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.1 ETS62432.1 - 0.016 14.2 0.4 0.024 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RRM_5 PF13893.1 ETS62432.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHD3 PF05879.7 ETS62433.1 - 5.1e-247 821.5 0.4 6.6e-247 821.1 0.3 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 ETS62433.1 - 4.4e-07 29.2 0.2 1.2e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 ETS62433.1 - 1.8e-05 24.6 0.0 4.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETS62433.1 - 2.6e-05 24.0 0.0 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 ETS62433.1 - 0.00014 22.3 0.5 0.00041 20.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 ETS62433.1 - 0.00031 20.7 0.0 0.001 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF2523 PF10734.4 ETS62433.1 - 0.035 14.3 0.1 0.084 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) PTS_IIA PF02255.11 ETS62433.1 - 0.079 12.8 2.3 0.22 11.4 1.6 1.7 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit AAA_16 PF13191.1 ETS62433.1 - 3.5 7.5 7.1 4.3 7.2 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain Pyr_redox_2 PF07992.9 ETS62434.1 - 1.6e-18 67.3 0.0 5e-14 52.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS62434.1 - 2e-10 40.8 0.2 1.2e-09 38.4 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS62434.1 - 0.00012 22.2 0.0 0.0019 18.2 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HSP20 PF00011.16 ETS62435.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family MRP-S33 PF08293.6 ETS62436.1 - 4e-23 81.1 0.1 5.2e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Peptidase_C14 PF00656.17 ETS62437.1 - 2.9e-64 217.1 0.1 3.7e-64 216.8 0.1 1.0 1 0 0 1 1 1 1 Caspase domain MBOAT PF03062.14 ETS62438.1 - 5.3e-48 163.7 1.4 5.3e-48 163.7 1.0 2.5 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Methyltransf_3 PF01596.12 ETS62439.1 - 2.5e-47 160.5 0.2 3.4e-47 160.1 0.2 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 ETS62439.1 - 8.1e-12 45.9 0.0 1.8e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS62439.1 - 9.3e-09 35.8 0.0 2.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS62439.1 - 3.8e-05 23.7 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS62439.1 - 0.002 17.7 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 ETS62439.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 ETS62439.1 - 0.044 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TBCC PF07986.7 ETS62440.1 - 2.2e-11 43.1 2.0 3.6e-11 42.5 1.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Chorismate_synt PF01264.16 ETS62441.1 - 1.9e-131 437.7 0.5 1.1e-64 218.1 0.1 2.0 2 0 0 2 2 2 2 Chorismate synthase EthD PF07110.6 ETS62442.1 - 8.9e-07 29.7 0.3 0.0047 17.8 0.0 2.5 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 ETS62442.1 - 0.042 14.1 0.0 9.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Coatomer_WDAD PF04053.9 ETS62443.1 - 1.2e-152 508.7 0.0 1.2e-151 505.5 0.0 2.3 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 ETS62443.1 - 1.4e-49 164.2 12.3 2.1e-11 43.2 0.3 7.9 9 0 0 9 9 9 6 WD domain, G-beta repeat TPR_2 PF07719.12 ETS62443.1 - 0.038 13.9 0.3 11 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BBS2_Mid PF14783.1 ETS62443.1 - 0.055 13.2 0.0 12 5.6 0.0 3.7 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MgtE_N PF03448.12 ETS62443.1 - 0.22 11.8 2.9 0.41 11.0 1.1 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain TPR_19 PF14559.1 ETS62443.1 - 1.2 9.5 6.0 1.3 9.3 0.5 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS62443.1 - 1.4 9.5 5.5 2.3 8.8 0.8 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps5 PF09325.5 ETS62444.1 - 1.5e-16 60.3 7.3 2.2e-16 59.8 5.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DUF2422 PF10337.4 ETS62444.1 - 0.52 9.0 6.5 0.85 8.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RNase_T PF00929.19 ETS62445.1 - 1.2e-25 90.7 0.0 1.7e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 ETS62445.1 - 0.048 13.1 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease 2-Hacid_dh_C PF02826.14 ETS62446.1 - 2.8e-52 176.4 0.0 4.6e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS62446.1 - 8.2e-15 54.4 0.0 1.2e-14 53.9 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS62446.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 ETS62446.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 ETS62446.1 - 0.02 15.3 0.2 0.095 13.1 0.0 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 ETS62446.1 - 0.03 14.8 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.22 ETS62446.1 - 0.034 14.5 0.1 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pectate_lyase_3 PF12708.2 ETS62447.1 - 2.4e-80 269.8 8.3 3.8e-63 213.6 2.7 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 ETS62447.1 - 3.2e-07 29.7 1.0 0.017 14.5 0.3 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 ETS62447.1 - 0.09 12.5 9.8 0.068 12.9 3.3 2.6 1 1 2 3 3 3 0 Right handed beta helix region PP2C PF00481.16 ETS62448.1 - 2.8e-65 220.2 0.1 5.9e-52 176.5 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 ETS62448.1 - 0.032 13.9 0.2 0.32 10.6 0.1 2.3 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) HMG_box PF00505.14 ETS62449.1 - 1.1e-20 73.5 14.4 1.8e-10 40.9 2.5 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box Methyltransf_16 PF10294.4 ETS62449.1 - 8.1e-18 64.4 0.4 1.2e-12 47.6 0.0 2.2 1 1 1 2 2 2 2 Putative methyltransferase HMG_box_2 PF09011.5 ETS62449.1 - 1.1e-17 64.0 11.0 8.3e-09 35.6 0.8 2.5 2 0 0 2 2 2 2 HMG-box domain Methyltransf_18 PF12847.2 ETS62449.1 - 0.0004 20.9 0.0 0.001 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS62449.1 - 0.01 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain YABBY PF04690.8 ETS62449.1 - 0.015 15.5 3.6 0.03 14.5 2.1 1.9 1 1 0 1 1 1 0 YABBY protein Methyltransf_31 PF13847.1 ETS62449.1 - 0.25 10.9 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF3275 PF11679.3 ETS62450.1 - 7.9 6.0 7.8 12 5.4 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) CRAL_TRIO PF00650.15 ETS62451.1 - 5.8e-36 123.3 0.1 9.3e-36 122.7 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS62451.1 - 4.5e-11 42.7 0.8 1.4e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CBF_beta PF02312.12 ETS62451.1 - 0.21 11.1 2.1 2.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Core binding factor beta subunit Acetyltransf_1 PF00583.19 ETS62452.1 - 1.1e-15 57.4 0.1 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETS62452.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETS62452.1 - 2.8e-05 24.1 0.0 3.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS62452.1 - 0.0004 20.2 0.0 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS62452.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS62452.1 - 0.019 14.9 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_H PF00075.19 ETS62454.1 - 0.0029 17.9 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 RNase H Corona_nucleoca PF00937.13 ETS62455.1 - 2.3 7.0 12.0 1.1 8.1 2.3 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Prenyltransf PF01255.14 ETS62456.1 - 3.1e-75 252.1 0.0 4e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_S26 PF10502.4 ETS62457.1 - 2.7e-06 26.9 0.0 0.00039 19.9 0.0 2.5 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 ETS62457.1 - 3.3e-05 23.4 0.0 0.00021 20.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like DUF3446 PF11928.3 ETS62457.1 - 2.3 8.4 6.1 0.25 11.5 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) RhoGEF PF00621.15 ETS62458.1 - 7.4e-25 87.8 0.1 5.6e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain PH PF00169.24 ETS62458.1 - 0.00057 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 PH domain DPBB_1 PF03330.13 ETS62459.1 - 0.0017 18.2 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel CAP_GLY PF01302.20 ETS62460.1 - 5.9e-21 73.9 0.1 8.9e-21 73.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 ETS62460.1 - 4.1e-16 58.1 9.3 1.5e-08 34.0 1.2 4.0 2 2 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS62460.1 - 1.3e-14 53.7 9.3 5.7e-10 38.8 0.9 3.8 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 ETS62460.1 - 2.3e-08 32.9 7.2 1.1 9.5 0.0 6.5 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 ETS62460.1 - 1.1e-05 24.7 11.1 8.9 7.0 0.0 6.6 5 1 1 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 ETS62460.1 - 5.4e-05 22.8 13.8 5.8 7.3 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.1 ETS62460.1 - 0.0023 17.5 0.1 0.21 11.1 0.0 2.8 1 1 1 2 2 2 2 Leucine-rich repeat DUF3661 PF12400.3 ETS62463.1 - 6.9e-40 136.1 0.4 9.8e-40 135.6 0.0 1.4 2 0 0 2 2 2 1 Vaculolar membrane protein GN3L_Grn1 PF08701.6 ETS62464.1 - 5.2e-24 83.9 17.3 5.2e-24 83.9 12.0 4.3 5 0 0 5 5 5 1 GNL3L/Grn1 putative GTPase SGT1 PF07093.6 ETS62464.1 - 0.00043 18.7 28.4 0.0035 15.7 6.2 2.6 3 0 0 3 3 3 2 SGT1 protein TFIIF_alpha PF05793.7 ETS62464.1 - 0.0023 16.3 31.9 0.0023 16.3 22.1 3.7 3 1 0 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.5 ETS62464.1 - 0.013 15.7 1.1 0.013 15.7 0.7 6.4 6 1 0 6 6 6 0 Centromere protein B dimerisation domain MMR_HSR1 PF01926.18 ETS62464.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Daxx PF03344.10 ETS62464.1 - 0.48 8.8 50.9 0.56 8.6 5.1 3.3 3 0 0 3 3 3 0 Daxx Family RRN3 PF05327.6 ETS62465.1 - 1.8e-186 620.5 0.0 2.6e-186 620.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Thioredoxin PF00085.15 ETS62466.1 - 3.7e-16 58.6 0.1 4.6e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ETS62466.1 - 2.3e-07 30.8 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 ETS62466.1 - 3.4e-05 23.7 0.1 4.4e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS62466.1 - 5.3e-05 23.3 0.0 7.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 ETS62466.1 - 0.00035 20.2 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.9 ETS62466.1 - 0.0031 17.7 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Redoxin PF08534.5 ETS62466.1 - 0.0083 15.6 0.3 0.015 14.8 0.1 1.5 1 1 0 1 1 1 1 Redoxin PhaP_Bmeg PF09602.5 ETS62466.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Glutaredoxin PF00462.19 ETS62466.1 - 0.15 12.0 0.8 0.42 10.6 0.6 1.8 1 1 0 1 1 1 0 Glutaredoxin Adaptin_N PF01602.15 ETS62469.1 - 8.5e-122 407.1 11.7 1e-121 406.8 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 ETS62469.1 - 8e-40 135.3 0.0 2.6e-39 133.6 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 ETS62469.1 - 3.1e-17 62.9 0.0 8.3e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain 14-3-3 PF00244.15 ETS62470.1 - 8.2e-118 391.6 5.6 1e-117 391.3 3.9 1.1 1 0 0 1 1 1 1 14-3-3 protein Ras PF00071.17 ETS62471.1 - 3e-50 169.7 0.0 3.6e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS62471.1 - 4.2e-16 59.5 0.0 6.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS62471.1 - 2.1e-10 40.0 0.0 2.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS62471.1 - 3.6e-05 23.0 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 ETS62471.1 - 0.0013 17.4 1.2 0.75 8.4 0.0 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 ETS62471.1 - 0.014 15.5 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 ETS62471.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 ETS62471.1 - 0.042 13.9 0.1 0.13 12.3 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETS62471.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 ETS62471.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain KaiC PF06745.8 ETS62471.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 KaiC SHS2_Rpb7-N PF03876.12 ETS62472.1 - 5e-05 23.3 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 FUSC PF04632.7 ETS62473.1 - 4.7e-15 55.0 9.3 4.7e-15 55.0 6.5 3.5 4 0 0 4 4 4 1 Fusaric acid resistance protein family FUSC_2 PF13515.1 ETS62473.1 - 2.1e-14 53.5 7.1 2.1e-14 53.5 4.9 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 ETS62473.1 - 8.1e-09 34.6 4.7 8.8e-09 34.4 1.1 2.2 2 0 0 2 2 2 1 Aluminium activated malate transporter DUF2422 PF10337.4 ETS62473.1 - 8.4e-07 28.1 6.9 6.1e-05 21.9 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF939 PF06081.6 ETS62473.1 - 7.7e-06 25.8 2.2 7.7e-06 25.8 1.5 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF939) DUF2421 PF10334.4 ETS62473.1 - 1.1e-05 25.1 1.1 2.6e-05 23.9 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) PTH2 PF01981.11 ETS62474.1 - 0.00073 19.2 0.3 0.0017 18.0 0.1 1.7 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DUF745 PF05335.8 ETS62474.1 - 0.14 11.7 5.3 0.25 10.8 3.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Sybindin PF04099.7 ETS62475.1 - 9.3e-34 116.1 0.0 1.5e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.8 ETS62475.1 - 6.5e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region LRRC37AB_C PF14914.1 ETS62475.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain PCI PF01399.22 ETS62476.1 - 4.8e-11 42.8 0.0 1.1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain Coatomer_E PF04733.9 ETS62478.1 - 1.9e-42 145.4 6.1 2.1e-42 145.2 4.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.1 ETS62478.1 - 5.1e-05 22.8 5.5 0.00049 19.6 0.3 3.5 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 ETS62478.1 - 0.013 15.6 0.6 0.42 10.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS62478.1 - 0.014 15.9 1.1 0.014 15.9 0.8 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS62478.1 - 0.083 13.2 14.6 5.7 7.3 1.5 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS62478.1 - 1.7 8.7 7.3 2.6 8.2 0.0 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 ETS62478.1 - 5.7 7.1 14.9 0.091 12.8 0.4 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 ETS62479.1 - 4.3e-76 256.1 0.1 6.2e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF3237 PF11578.3 ETS62480.1 - 3.9e-29 100.8 0.0 4.6e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) BAF1_ABF1 PF04684.8 ETS62481.1 - 6.1 5.5 21.3 0.51 9.1 10.9 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor F-box-like PF12937.2 ETS62482.1 - 1.1e-11 44.2 3.6 1.1e-11 44.2 2.5 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 ETS62482.1 - 1.8e-08 33.8 0.6 0.087 12.4 0.0 5.7 3 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS62482.1 - 2.8e-06 26.6 10.5 11 6.5 0.0 7.8 7 3 1 8 8 8 2 Leucine Rich Repeat F-box PF00646.28 ETS62482.1 - 1.8e-05 24.2 5.8 4.1e-05 23.1 0.8 3.4 4 0 0 4 4 4 1 F-box domain LRR_8 PF13855.1 ETS62482.1 - 5e-05 22.9 10.6 0.94 9.2 0.0 5.7 3 2 3 6 6 6 4 Leucine rich repeat Ste50p-SAM PF09235.5 ETS62482.1 - 0.22 11.5 2.8 21 5.2 0.0 3.6 3 0 0 3 3 3 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 ETS62482.1 - 1.7 9.1 17.0 50 4.7 0.0 7.2 8 0 0 8 8 8 0 Leucine rich repeat DUF4611 PF15387.1 ETS62483.1 - 0.007 16.4 0.8 0.0094 16.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) DUF3651 PF12371.3 ETS62483.1 - 0.016 15.2 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3651) P21-Arc PF04062.9 ETS62484.1 - 1.8e-74 249.2 0.0 2e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Asp_protease PF09668.5 ETS62485.1 - 1.8e-60 201.9 0.1 2.7e-60 201.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 ETS62485.1 - 1.8e-11 44.4 0.0 5.1e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 ETS62485.1 - 3e-09 36.1 0.0 6.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 ETS62485.1 - 7.3e-07 28.9 0.0 2.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 ETS62485.1 - 0.00013 21.6 0.2 0.00075 19.2 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain RVP_2 PF08284.6 ETS62485.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 ETS62485.1 - 0.00016 21.5 0.0 0.00044 20.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 ETS62485.1 - 0.00024 20.5 1.5 0.00032 20.1 0.2 1.8 2 0 0 2 2 2 1 UBA-like domain XPC-binding PF09280.6 ETS62485.1 - 0.00046 19.5 4.3 0.0013 18.1 3.0 1.7 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 ETS62485.1 - 0.00054 19.5 0.1 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mob1_phocein PF03637.12 ETS62486.1 - 3.4e-56 189.6 0.2 4.1e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family ABC_tran PF00005.22 ETS62487.1 - 7.4e-45 152.6 0.0 3.7e-22 79.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 ETS62487.1 - 1.4e-20 72.8 2.9 1.4e-20 72.8 2.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 ETS62487.1 - 4.1e-19 69.6 0.7 0.00099 19.1 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 ETS62487.1 - 3.9e-09 35.9 0.5 0.0009 18.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 ETS62487.1 - 1e-07 31.4 2.3 0.47 9.6 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 ETS62487.1 - 1.1e-07 32.3 0.0 0.013 15.9 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 ETS62487.1 - 4.3e-07 30.4 17.7 0.00078 19.8 0.9 4.3 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 ETS62487.1 - 1.4e-06 29.1 0.1 0.067 14.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 ETS62487.1 - 3.2e-06 26.4 0.0 0.0015 17.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS62487.1 - 6.7e-06 26.2 1.0 0.28 11.3 0.1 4.0 2 2 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 ETS62487.1 - 7.7e-06 25.8 3.2 0.1 12.3 0.0 4.1 2 1 1 3 3 3 2 Dynamin family AAA_25 PF13481.1 ETS62487.1 - 1.1e-05 24.8 0.1 0.57 9.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 ETS62487.1 - 1.1e-05 25.2 1.1 0.0064 16.4 0.2 3.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.7 ETS62487.1 - 4.9e-05 23.0 0.8 0.34 10.5 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 ETS62487.1 - 7.9e-05 21.8 9.5 0.24 10.3 0.0 4.7 4 1 1 5 5 5 2 AAA ATPase domain AAA_18 PF13238.1 ETS62487.1 - 0.00028 21.2 1.3 0.72 10.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 ETS62487.1 - 0.00028 20.9 0.5 0.17 11.8 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS62487.1 - 0.0005 19.5 0.1 0.44 9.9 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 ETS62487.1 - 0.00068 19.1 0.4 0.44 9.9 0.1 3.0 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 ETS62487.1 - 0.00087 19.4 1.5 3.3 7.9 0.0 4.1 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 ETS62487.1 - 0.001 18.3 0.1 0.069 12.4 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_28 PF13521.1 ETS62487.1 - 0.0012 18.8 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 ETS62487.1 - 0.002 17.8 5.1 0.29 10.8 0.1 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 ETS62487.1 - 0.003 17.1 0.0 0.49 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS62487.1 - 0.003 17.2 0.2 1.6 8.5 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 ETS62487.1 - 0.0037 17.1 0.0 0.82 9.6 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 ETS62487.1 - 0.0097 15.5 1.2 4.6 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 ETS62487.1 - 0.01 15.7 0.1 16 5.3 0.0 4.0 4 0 0 4 4 4 0 AAA domain T2SE PF00437.15 ETS62487.1 - 0.01 14.7 0.5 2.1 7.1 0.1 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.9 ETS62487.1 - 0.016 14.9 0.5 0.81 9.4 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 ETS62487.1 - 0.018 14.9 0.2 8.3 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 ETS62487.1 - 0.023 14.1 0.1 4.1 6.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.4 ETS62487.1 - 0.023 13.6 1.0 3.5 6.4 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 ETS62487.1 - 0.026 13.3 0.0 4.7 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Pox_A32 PF04665.7 ETS62487.1 - 0.032 13.5 1.1 5.6 6.1 0.1 3.1 2 1 1 3 3 3 0 Poxvirus A32 protein RNA_helicase PF00910.17 ETS62487.1 - 0.032 14.4 0.5 3.3 7.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase SRP54 PF00448.17 ETS62487.1 - 0.048 13.1 2.2 1.5 8.2 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 ETS62487.1 - 0.064 13.0 8.1 0.83 9.4 0.0 4.2 3 1 1 4 4 4 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 ETS62487.1 - 0.074 12.5 0.8 11 5.5 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 ETS62487.1 - 1.7 8.3 5.7 3.5 7.3 0.1 3.4 5 0 0 5 5 3 0 NTPase DivIC PF04977.10 ETS62487.1 - 4.8 6.7 16.1 1.2 8.6 1.2 3.1 3 0 0 3 3 3 0 Septum formation initiator Ribosomal_L23eN PF03939.8 ETS62487.1 - 7.9 6.5 8.8 27 4.8 6.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain MRP-L27 PF09809.4 ETS62488.1 - 6.4e-05 22.5 1.6 0.0033 17.0 1.1 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Fib_alpha PF08702.5 ETS62489.1 - 0.45 10.6 3.1 14 5.8 0.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SPRY PF00622.23 ETS62490.1 - 2.4e-06 27.6 0.0 1.1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 SPRY domain DEAD PF00270.24 ETS62492.1 - 4.3e-42 143.4 0.0 7.1e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS62492.1 - 3.3e-23 81.3 0.0 7.4e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS62492.1 - 0.0025 17.6 0.0 0.0093 15.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Erv26 PF04148.8 ETS62493.1 - 1.1e-11 44.5 6.8 1.6e-10 40.6 4.7 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Acyl-CoA_dh_N PF02771.11 ETS62494.1 - 1.1e-26 93.5 0.0 2.3e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 ETS62494.1 - 5.1e-25 88.3 0.0 7.4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS62494.1 - 7.2e-20 70.2 0.1 5.2e-19 67.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS62494.1 - 1.2e-09 38.4 0.0 2.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mod_r PF07200.8 ETS62496.1 - 4.8e-19 68.7 8.7 2.1e-17 63.4 2.0 2.3 3 0 0 3 3 3 2 Modifier of rudimentary (Mod(r)) protein NUDIX PF00293.23 ETS62497.1 - 4.2e-14 52.3 0.0 6.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PNRC PF15365.1 ETS62498.1 - 0.012 15.5 2.1 0.048 13.6 1.5 2.0 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Iso_dh PF00180.15 ETS62499.1 - 1e-79 268.0 0.0 1.3e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COesterase PF00135.23 ETS62500.1 - 1.5e-72 245.0 0.0 3.9e-71 240.3 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DnaJ PF00226.26 ETS62500.1 - 3.4e-14 52.3 0.2 9.1e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.8 ETS62500.1 - 1.6e-11 43.5 0.6 3e-11 42.6 0.4 1.5 1 0 0 1 1 1 1 CSL zinc finger Abhydrolase_3 PF07859.8 ETS62500.1 - 1.4e-05 24.7 0.0 0.00064 19.3 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold ZZ PF00569.12 ETS62500.1 - 0.065 12.7 0.4 0.44 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type Ribosomal_L18e PF00828.14 ETS62502.1 - 2.8e-20 73.0 1.5 6.8e-19 68.5 0.0 2.5 2 1 1 3 3 3 1 Ribosomal protein L18e/L15 Hyphal_reg_CWP PF11765.3 ETS62502.1 - 0.06 12.0 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal VID27 PF08553.5 ETS62503.1 - 0 1052.1 2.0 0 1051.8 1.4 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein eIF-3_zeta PF05091.7 ETS62504.1 - 7.9e-187 621.9 0.0 9.2e-187 621.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 ETS62505.1 - 8.7e-42 143.0 0.0 1e-23 83.8 0.0 2.6 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62505.1 - 7.8e-13 48.0 0.0 9.3e-10 38.0 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 ETS62505.1 - 0.0024 17.6 0.0 0.021 14.5 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS62505.1 - 0.048 12.7 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAP18 PF06487.7 ETS62506.1 - 1.9e-13 50.2 0.0 3.4e-13 49.4 0.0 1.3 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Rad60-SLD PF11976.3 ETS62506.1 - 0.11 12.1 0.7 16 5.2 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L7Ae PF01248.21 ETS62507.1 - 1e-28 98.6 0.8 1.3e-28 98.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S17 PF00366.15 ETS62508.1 - 4.5e-30 103.5 2.7 6.4e-30 102.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Clathrin_lg_ch PF01086.12 ETS62509.1 - 6.6e-35 121.0 13.9 1.9e-32 113.0 9.6 2.1 1 1 0 1 1 1 1 Clathrin light chain PhoU PF01895.14 ETS62509.1 - 0.13 12.7 1.6 0.22 11.9 1.1 1.4 1 0 0 1 1 1 0 PhoU domain Metallophos PF00149.23 ETS62510.1 - 2.4e-42 144.6 0.7 3.2e-42 144.1 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ACC_central PF08326.7 ETS62510.1 - 0.14 10.2 0.1 0.23 9.5 0.1 1.2 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region FAD-oxidase_C PF02913.14 ETS62511.1 - 2.2e-59 200.7 0.0 3.3e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS62511.1 - 2.7e-35 120.8 1.0 4.8e-35 120.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Ilar_coat PF01787.11 ETS62511.1 - 0.0065 16.0 0.2 0.24 10.9 0.0 2.7 3 0 0 3 3 3 1 Ilarvirus coat protein EpuA PF11772.3 ETS62511.1 - 0.082 12.3 0.3 0.21 11.0 0.2 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Cid2 PF09774.4 ETS62512.1 - 1.1e-34 119.6 0.0 1.5e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Clathrin PF00637.15 ETS62513.1 - 1.2e-23 83.2 0.1 8.7e-23 80.5 0.0 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 ETS62513.1 - 0.00079 19.2 0.9 0.084 12.7 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 ETS62513.1 - 0.2 11.5 0.4 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Ring finger domain GRIM-19 PF06212.7 ETS62514.1 - 2e-36 124.5 0.0 3e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein Nop14 PF04147.7 ETS62515.1 - 2.7e-252 839.4 18.6 5.5e-252 838.4 12.9 1.4 1 1 0 1 1 1 1 Nop14-like family TIP41 PF04176.8 ETS62516.1 - 2.8e-44 150.5 0.2 1.1e-39 135.5 0.2 2.8 2 1 0 2 2 2 2 TIP41-like family zf-CCCH PF00642.19 ETS62517.1 - 2.7e-05 23.7 1.3 4.8e-05 22.9 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETS62517.1 - 0.57 10.2 6.0 1.3 9.1 4.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type UPF0560 PF10577.4 ETS62517.1 - 8.6 4.4 9.6 12 3.9 6.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 WD40 PF00400.27 ETS62518.1 - 4e-23 80.3 9.3 0.00023 20.9 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 ETS62518.1 - 0.019 15.2 1.4 4.5 7.6 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain Transglut_core2 PF13369.1 ETS62519.1 - 3.4e-15 55.8 0.0 5e-14 52.0 0.0 2.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.6 ETS62519.1 - 7.1e-15 54.7 0.0 2.7e-12 46.5 0.0 2.8 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.2 ETS62519.1 - 2.3e-08 33.6 0.0 7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS62519.1 - 2.2e-05 23.9 0.0 8.6e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain NOB1_Zn_bind PF08772.6 ETS62520.1 - 2.7e-31 107.2 2.1 5.4e-31 106.2 1.4 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-TFIIIC PF12660.2 ETS62520.1 - 0.03 14.2 0.6 0.15 12.0 0.2 2.2 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex OGG_N PF07934.7 ETS62521.1 - 1.3e-25 89.6 0.0 2.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 ETS62521.1 - 3.4e-14 53.0 0.0 7.7e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETS62521.1 - 0.023 14.3 0.0 0.064 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif GLE1 PF07817.8 ETS62522.1 - 4.4e-72 242.0 0.0 7.5e-72 241.3 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein Ycf1 PF05758.7 ETS62522.1 - 10 3.7 7.0 14 3.1 4.8 1.2 1 0 0 1 1 1 0 Ycf1 AAA PF00004.24 ETS62526.1 - 2.3e-92 306.0 0.0 1.9e-46 157.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS62526.1 - 4.6e-15 55.2 0.0 5.1e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETS62526.1 - 1.3e-11 44.4 0.3 0.00073 19.2 0.1 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS62526.1 - 2.6e-11 43.7 0.8 0.0024 18.0 0.0 5.0 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.9 ETS62526.1 - 9.9e-11 41.8 0.0 0.00049 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 ETS62526.1 - 4.8e-10 39.4 0.0 0.0027 17.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS62526.1 - 7.2e-10 39.1 9.1 0.0012 18.9 0.0 4.8 3 2 1 5 5 4 2 AAA ATPase domain AAA_17 PF13207.1 ETS62526.1 - 8.9e-10 39.4 0.0 9.6e-05 23.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 ETS62526.1 - 6e-09 35.1 0.5 0.00022 20.0 0.0 2.8 2 1 1 3 3 3 2 TIP49 C-terminus AAA_14 PF13173.1 ETS62526.1 - 1.7e-08 34.4 0.0 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ETS62526.1 - 1.4e-07 30.7 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 ETS62526.1 - 2.7e-07 30.2 1.8 0.03 14.0 0.0 3.7 4 0 0 4 4 3 2 Part of AAA domain Mg_chelatase PF01078.16 ETS62526.1 - 3.6e-07 29.5 0.4 0.029 13.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 ETS62526.1 - 8.2e-07 28.8 1.7 0.064 12.9 0.1 4.2 4 1 1 5 5 4 2 NACHT domain IstB_IS21 PF01695.12 ETS62526.1 - 8.4e-07 28.5 0.7 0.012 15.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 ETS62526.1 - 1.6e-06 28.2 0.0 0.059 13.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 ETS62526.1 - 3.5e-06 27.0 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 ETS62526.1 - 8.2e-06 26.1 0.0 0.031 14.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.6 ETS62526.1 - 1.2e-05 24.8 0.0 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETS62526.1 - 1.6e-05 24.4 6.6 0.82 9.0 0.1 4.4 2 2 2 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.1 ETS62526.1 - 7.1e-05 22.8 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 ETS62526.1 - 0.00012 21.3 0.1 1.2 8.2 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.1 ETS62526.1 - 0.00013 22.2 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 ETS62526.1 - 0.00019 20.9 0.0 0.34 10.3 0.0 3.5 3 1 0 3 3 3 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 ETS62526.1 - 0.00024 21.0 0.0 0.074 12.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Viral_helicase1 PF01443.13 ETS62526.1 - 0.00045 19.8 0.0 0.81 9.1 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 ETS62526.1 - 0.00048 19.0 0.1 0.32 9.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain SKI PF01202.17 ETS62526.1 - 0.00098 19.0 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase PhoH PF02562.11 ETS62526.1 - 0.0013 18.0 0.6 1.1 8.3 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein DUF815 PF05673.8 ETS62526.1 - 0.0013 17.6 0.0 0.028 13.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 ETS62526.1 - 0.006 16.3 0.0 1.8 8.2 0.0 3.0 2 2 1 3 3 3 1 Archaeal ATPase Rad17 PF03215.10 ETS62526.1 - 0.0077 14.9 0.0 2 7.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AFG1_ATPase PF03969.11 ETS62526.1 - 0.009 14.8 0.0 1.2 7.8 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 ETS62526.1 - 0.011 15.5 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 ETS62526.1 - 0.014 14.9 0.1 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 ETS62526.1 - 0.014 14.9 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETS62526.1 - 0.015 14.9 0.2 6.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 ETS62526.1 - 0.017 14.0 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 ETS62526.1 - 0.021 14.5 0.1 2.7 7.6 0.0 2.7 2 1 1 3 3 2 0 NTPase PduV-EutP PF10662.4 ETS62526.1 - 0.16 11.4 0.0 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 ETS62526.1 - 0.28 10.8 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein TB2_DP1_HVA22 PF03134.14 ETS62527.1 - 9.1e-08 31.7 0.5 1.6e-07 30.9 0.4 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Macoilin PF09726.4 ETS62527.1 - 4.4 5.4 19.0 0.97 7.6 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein IMS PF00817.15 ETS62528.1 - 5.1e-39 133.4 0.0 1e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETS62528.1 - 5.9e-18 65.0 0.0 1.5e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cyt-b5 PF00173.23 ETS62528.1 - 3.8e-13 49.0 0.3 6.4e-09 35.4 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DUF4414 PF14377.1 ETS62528.1 - 0.011 15.6 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) PCI_Csn8 PF10075.4 ETS62530.1 - 7.1e-33 113.3 0.1 9.9e-33 112.9 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 ETS62530.1 - 9.2e-30 103.7 0.0 1.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HAUS6_N PF14661.1 ETS62531.1 - 0.024 14.0 8.6 0.044 13.1 5.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Mus7 PF09462.5 ETS62531.1 - 0.07 11.9 0.9 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Mus7/MMS22 family GBP_C PF02841.9 ETS62531.1 - 2.2 7.3 11.4 3.9 6.5 7.9 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain OmpH PF03938.9 ETS62531.1 - 5.2 6.9 12.6 11 5.8 8.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TRAPP PF04051.11 ETS62532.1 - 1.4e-39 135.0 0.0 1.8e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component He_PIG PF05345.7 ETS62533.1 - 6.2e-10 38.9 14.9 0.00039 20.3 1.1 4.3 3 1 0 3 3 3 3 Putative Ig domain PP2C PF00481.16 ETS62536.1 - 4e-32 111.5 0.0 1.4e-28 100.0 0.0 2.9 2 1 1 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 ETS62536.1 - 0.06 12.7 0.0 0.06 12.7 0.0 2.0 3 0 0 3 3 3 0 Protein phosphatase 2C BrkDBD PF09607.5 ETS62536.1 - 0.089 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Brinker DNA-binding domain NUDIX PF00293.23 ETS62537.1 - 1.2e-12 47.6 0.2 1.5e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 ETS62538.1 - 3.7e-54 182.4 0.0 5.7e-38 130.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS62538.1 - 1.6e-09 38.0 2.0 0.00025 21.1 0.2 4.1 3 2 1 4 4 3 2 AAA domain CDC48_2 PF02933.12 ETS62538.1 - 2e-09 36.9 0.1 2.5e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 ETS62538.1 - 2.5e-08 34.1 0.0 0.0085 16.0 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 ETS62538.1 - 3.5e-08 33.2 0.1 0.0015 18.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS62538.1 - 3.7e-08 33.3 0.0 0.001 18.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 ETS62538.1 - 4.3e-08 33.2 0.1 0.00031 20.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 ETS62538.1 - 3.1e-07 31.2 0.0 0.021 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS62538.1 - 3.2e-07 30.3 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 ETS62538.1 - 3.2e-07 29.6 0.1 0.01 14.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 ETS62538.1 - 4.5e-07 28.9 0.0 0.0059 15.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 ETS62538.1 - 4.6e-07 29.5 6.1 0.0096 15.6 0.2 3.4 4 0 0 4 4 2 2 Part of AAA domain NACHT PF05729.7 ETS62538.1 - 4.9e-07 29.5 0.2 0.028 14.0 0.0 3.5 3 1 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.12 ETS62538.1 - 1.1e-06 28.2 0.5 0.022 14.1 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 ETS62538.1 - 1.7e-06 27.3 0.8 0.0087 15.2 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 ETS62538.1 - 4.2e-06 26.4 2.3 0.015 14.8 0.1 2.7 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 ETS62538.1 - 5.4e-06 26.5 0.0 0.026 14.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 ETS62538.1 - 6.1e-06 26.5 0.1 0.033 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 ETS62538.1 - 2.4e-05 24.6 0.6 0.16 12.2 0.1 3.3 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 ETS62538.1 - 3.9e-05 23.6 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ETS62538.1 - 5.5e-05 22.3 0.1 0.068 12.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin PhoH PF02562.11 ETS62538.1 - 6.1e-05 22.3 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.1 ETS62538.1 - 6.5e-05 22.4 5.8 0.26 10.6 0.2 3.9 2 2 1 3 3 3 2 AAA domain Arch_ATPase PF01637.13 ETS62538.1 - 7.5e-05 22.5 0.6 0.28 10.8 0.1 3.7 2 2 1 4 4 4 1 Archaeal ATPase NB-ARC PF00931.17 ETS62538.1 - 0.00015 20.7 0.1 0.35 9.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 ETS62538.1 - 0.00023 20.6 0.0 0.51 9.7 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 ETS62538.1 - 0.00041 19.5 0.1 0.11 11.5 0.0 2.6 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.12 ETS62538.1 - 0.00054 18.9 0.0 0.49 9.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 ETS62538.1 - 0.00055 19.5 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 ETS62538.1 - 0.00062 19.3 0.0 0.45 10.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 ETS62538.1 - 0.001 18.7 0.0 0.47 9.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETS62538.1 - 0.0013 17.8 0.1 0.38 9.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 ETS62538.1 - 0.0023 17.9 0.4 1.7 8.6 0.1 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 ETS62538.1 - 0.0027 17.3 0.0 0.68 9.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 ETS62538.1 - 0.0048 15.8 0.0 1.3 7.9 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DEAD PF00270.24 ETS62538.1 - 0.0097 15.4 0.9 17 4.8 0.0 4.0 4 1 1 5 5 4 0 DEAD/DEAH box helicase KTI12 PF08433.5 ETS62538.1 - 0.01 15.0 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.14 ETS62538.1 - 0.014 14.8 0.2 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 ETS62538.1 - 0.02 14.3 0.0 6.8 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain CDC48_N PF02359.13 ETS62538.1 - 0.023 14.6 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain TCTP PF00838.12 ETS62539.1 - 2.2e-65 219.6 0.2 2.6e-65 219.4 0.2 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.4 ETS62539.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC Zn_clus PF00172.13 ETS62540.1 - 0.051 13.5 4.5 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP PF00616.14 ETS62541.1 - 3.2e-33 115.0 0.0 6.1e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 ETS62541.1 - 3.2e-09 36.8 0.9 1.5e-08 34.6 0.1 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain BAF1_ABF1 PF04684.8 ETS62541.1 - 3.8 6.2 33.0 6.8 5.4 22.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EF-hand_1 PF00036.27 ETS62542.1 - 2.8e-27 91.8 11.5 1e-07 30.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETS62542.1 - 1.5e-24 85.8 3.6 1.4e-11 44.3 0.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETS62542.1 - 2.9e-21 73.7 13.1 2.4e-07 29.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 ETS62542.1 - 1.2e-20 71.5 8.3 1.6e-05 24.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETS62542.1 - 4.7e-16 58.1 12.3 1.4e-05 24.5 0.7 4.6 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETS62542.1 - 6.7e-06 26.1 0.0 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETS62542.1 - 2.3e-05 24.0 6.9 0.0056 16.3 0.2 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETS62542.1 - 2.9e-05 23.8 0.1 0.074 12.9 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain VCBS PF13517.1 ETS62542.1 - 0.018 15.3 0.6 8.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Proteasome PF00227.21 ETS62543.1 - 1.6e-43 148.2 0.2 1.8e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Vac14_Fig4_bd PF11916.3 ETS62544.1 - 9.3e-81 269.3 8.6 8e-80 266.2 5.2 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 ETS62544.1 - 1.3e-44 150.5 0.0 3.1e-40 136.4 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 ETS62544.1 - 1.7e-13 49.3 6.9 0.00018 21.3 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 ETS62544.1 - 8.1e-10 38.8 4.5 0.2 11.9 0.0 5.7 5 1 1 6 6 5 3 HEAT repeats HEAT_EZ PF13513.1 ETS62544.1 - 6e-05 23.3 5.3 2 9.0 0.0 6.0 6 1 1 7 7 6 2 HEAT-like repeat MMS19_C PF12460.3 ETS62544.1 - 0.0018 17.0 0.4 0.021 13.5 0.0 2.6 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 ETS62544.1 - 0.0022 17.3 1.3 11 5.2 0.0 4.5 4 1 0 5 5 5 1 CLASP N terminal Cnd1 PF12717.2 ETS62544.1 - 0.0042 16.9 3.3 1.8 8.4 0.1 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 ETS62544.1 - 0.035 13.9 0.2 6.5 6.6 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein CENP-B_dimeris PF09026.5 ETS62544.1 - 0.047 13.9 2.9 0.1 12.8 2.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.13 ETS62544.1 - 0.7 8.9 9.8 1.7 7.7 6.8 1.6 1 0 0 1 1 1 0 Myc amino-terminal region UCH PF00443.24 ETS62545.1 - 3e-54 183.9 0.0 5.2e-54 183.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS62545.1 - 3.8e-22 79.0 0.0 8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 ETS62545.1 - 0.0087 15.3 0.0 1.1 8.4 0.0 3.0 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.2 ETS62545.1 - 0.087 12.6 0.2 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon TBCA PF02970.11 ETS62546.1 - 1.4e-28 98.7 1.9 1.8e-28 98.4 1.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A TUG-UBL1 PF11470.3 ETS62546.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Nairo_nucleo PF02477.10 ETS62546.1 - 0.13 10.8 0.2 0.16 10.6 0.2 1.0 1 0 0 1 1 1 0 Nucleocapsid N protein Prefoldin_2 PF01920.15 ETS62546.1 - 0.23 11.2 2.5 0.19 11.4 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit CAP_N PF01213.14 ETS62547.1 - 0.76 9.0 3.4 1.1 8.4 2.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Med3 PF11593.3 ETS62547.1 - 1.3 8.1 4.1 1.8 7.7 2.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cpn60_TCP1 PF00118.19 ETS62548.1 - 8.7e-144 479.7 11.4 9.9e-144 479.5 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 ETS62548.1 - 0.0055 15.9 0.1 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Telomere recombination ATP-synt_Eps PF04627.8 ETS62548.1 - 5.9 6.5 5.4 3.8 7.1 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain LSM PF01423.17 ETS62549.1 - 9.8e-20 69.8 0.0 1.1e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 ETS62549.1 - 0.0032 17.3 0.0 0.0038 17.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_2 PF13347.1 ETS62550.1 - 5.4e-12 44.8 4.4 5.4e-12 44.8 3.0 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 ETS62550.1 - 4.1e-09 35.6 25.8 9.5e-09 34.4 8.3 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 ETS62550.1 - 0.00041 19.1 4.1 0.00071 18.4 2.8 1.3 1 0 0 1 1 1 1 PUCC protein Sugar_tr PF00083.19 ETS62550.1 - 0.0032 16.0 3.8 0.0073 14.9 0.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter zf-met2 PF12907.2 ETS62551.1 - 6.9e-08 32.3 4.5 6.9e-08 32.3 3.1 1.7 2 0 0 2 2 2 1 Zinc-binding zf-Di19 PF05605.7 ETS62551.1 - 0.0019 18.2 2.2 0.0034 17.4 1.5 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding 4F5 PF04419.9 ETS62551.1 - 0.024 15.3 12.2 0.039 14.6 8.4 1.3 1 0 0 1 1 1 0 4F5 protein family zf-C2H2_4 PF13894.1 ETS62551.1 - 0.049 13.9 2.1 0.067 13.5 0.4 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1644 PF07800.7 ETS62551.1 - 0.17 11.7 2.0 0.38 10.6 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) MDM31_MDM32 PF08118.6 ETS62552.1 - 1.5e-127 426.1 6.8 2.5e-62 210.9 0.2 3.0 2 1 1 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins CMV_1a PF12467.3 ETS62552.1 - 1.4 9.2 6.2 10 6.4 0.1 2.7 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Peptidase_M24 PF00557.19 ETS62553.1 - 1.7e-44 151.8 0.0 2.5e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ETS62553.1 - 1.4e-19 70.8 0.3 5.3e-17 62.5 0.0 3.1 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Glyoxal_oxid_N PF07250.6 ETS62555.1 - 3.6e-36 124.4 0.1 1.6e-32 112.5 0.0 3.7 2 2 1 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 ETS62555.1 - 8e-20 70.7 0.4 1.8e-19 69.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) EphA2_TM PF14575.1 ETS62555.1 - 0.72 10.2 0.0 0.72 10.2 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 ETS62555.1 - 3.1 7.1 4.9 6 6.2 3.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_L11_N PF03946.9 ETS62556.1 - 5e-18 64.3 0.1 7.9e-18 63.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 ETS62556.1 - 1.5e-11 44.2 0.4 2.8e-11 43.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain WD40 PF00400.27 ETS62557.1 - 9.2e-64 209.2 22.0 2.2e-11 43.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETS62557.1 - 3.6e-05 22.1 5.4 0.017 13.3 0.3 3.5 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETS62557.1 - 0.021 13.5 1.2 1.6 7.3 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETS62557.1 - 0.022 13.0 0.1 0.73 8.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 ETS62557.1 - 0.067 12.8 1.4 45 3.8 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1416 PF07210.7 ETS62557.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Thymidylat_synt PF00303.14 ETS62558.1 - 2.3e-112 374.4 0.0 3.8e-112 373.7 0.0 1.3 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 ETS62558.1 - 1.3e-28 100.0 0.0 1.1e-27 97.0 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Sec23_trunk PF04811.10 ETS62559.1 - 1e-58 198.5 0.0 3.2e-58 196.9 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETS62559.1 - 1.8e-25 88.3 0.1 3.2e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 ETS62559.1 - 7e-20 71.3 0.0 1.4e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 ETS62559.1 - 1.2e-17 63.1 2.7 2.4e-17 62.1 1.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 ETS62559.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat peroxidase PF00141.18 ETS62560.1 - 1.1e-47 162.4 0.0 1.8e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase UPF0139 PF03669.8 ETS62563.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) CBP4 PF07960.6 ETS62564.1 - 9.8e-13 47.8 0.0 1.2e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4414 PF14377.1 ETS62564.1 - 0.0022 17.9 0.3 0.0025 17.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) DUF3098 PF11297.3 ETS62564.1 - 0.023 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) SIP PF04954.8 ETS62564.1 - 0.061 13.7 0.5 0.068 13.5 0.3 1.0 1 0 0 1 1 1 0 Siderophore-interacting protein DUF4574 PF15141.1 ETS62564.1 - 0.088 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) Sugar_tr PF00083.19 ETS62565.1 - 1.2e-75 254.7 12.9 1.5e-75 254.4 9.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS62565.1 - 1.4e-19 69.9 15.0 1.4e-19 69.9 10.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4233 PF14017.1 ETS62565.1 - 3.4 7.6 14.0 0.23 11.4 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) HEAT PF02985.17 ETS62566.1 - 6.3e-20 69.4 14.1 0.00037 20.3 0.0 10.3 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.1 ETS62566.1 - 1.7e-18 66.6 14.9 4.3e-08 33.3 0.0 7.4 3 2 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 ETS62566.1 - 1.6e-16 60.1 21.9 2.4e-08 34.2 0.0 8.5 7 1 1 8 8 8 5 HEAT-like repeat IBN_N PF03810.14 ETS62566.1 - 1.5e-10 40.8 0.5 1.4e-08 34.5 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 ETS62566.1 - 8e-08 31.8 10.6 0.0096 15.7 0.0 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 ETS62566.1 - 0.0055 15.0 0.3 0.18 10.0 0.0 3.3 3 2 2 5 5 5 1 Adaptin N terminal region HEAT_PBS PF03130.11 ETS62566.1 - 0.015 15.6 4.6 25 5.7 0.0 5.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TIP120 PF08623.5 ETS62566.1 - 0.03 13.8 0.5 0.44 10.1 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) CLASP_N PF12348.3 ETS62566.1 - 0.039 13.3 0.1 55 2.9 0.0 4.1 4 1 1 5 5 5 0 CLASP N terminal Proteasom_PSMB PF10508.4 ETS62566.1 - 0.049 11.8 0.1 4.2 5.5 0.1 2.6 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 ETS62566.1 - 0.3 9.7 0.4 3.8 6.1 0.0 2.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal STE3 PF02076.10 ETS62568.1 - 2.1e-85 286.2 12.8 2.4e-85 286.0 8.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF3184 PF11380.3 ETS62569.1 - 2.9e-05 22.2 0.0 0.027 12.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3184) Sen15 PF09631.5 ETS62570.1 - 2e-12 47.2 0.1 2.8e-12 46.7 0.1 1.5 1 1 0 1 1 1 1 Sen15 protein Polysacc_deac_1 PF01522.16 ETS62571.1 - 1.3e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DAHP_synth_1 PF00793.15 ETS62572.1 - 2e-94 315.2 0.0 2.4e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_S19 PF00203.16 ETS62573.1 - 2e-23 81.8 0.0 2.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 OPT PF03169.10 ETS62574.1 - 3.5e-153 511.3 41.8 4e-153 511.1 29.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DEC-1_N PF04625.8 ETS62575.1 - 0.017 13.8 1.3 0.021 13.5 0.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Plectin PF00681.15 ETS62575.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Plectin repeat P16-Arc PF04699.9 ETS62576.1 - 1.5e-47 161.4 0.0 1.6e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) AviRa PF11599.3 ETS62576.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa DUF1296 PF06972.6 ETS62576.1 - 0.033 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Fungal_trans PF04082.13 ETS62577.1 - 9.7e-13 47.5 0.0 1.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS62577.1 - 2.8e-06 27.1 8.8 5e-06 26.3 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHF5 PF03660.9 ETS62578.1 - 0.049 13.6 0.1 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 PHF5-like protein ArfGap PF01412.13 ETS62582.1 - 2.6e-36 123.9 0.4 5.3e-36 122.9 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 ETS62582.1 - 2.8e-10 40.3 0.0 6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 PH domain tRNA-synt_1c PF00749.16 ETS62583.1 - 3.1e-80 269.1 0.0 4.5e-80 268.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Rft-1 PF04506.8 ETS62584.1 - 6.5e-73 245.9 0.1 2.7e-72 243.8 0.0 1.7 1 1 0 1 1 1 1 Rft protein COQ7 PF03232.8 ETS62584.1 - 0.14 11.5 0.0 8.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 HNH_3 PF13392.1 ETS62586.1 - 0.01 15.1 2.1 0.025 13.9 1.4 1.6 1 1 0 1 1 1 0 HNH endonuclease Kelch_3 PF13415.1 ETS62587.1 - 4.3e-16 58.5 9.6 3.3e-05 23.9 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS62587.1 - 1.7e-14 53.3 0.3 0.00093 19.1 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 ETS62587.1 - 2.4e-11 43.2 1.1 0.00047 19.8 0.0 5.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETS62587.1 - 2.4e-09 36.9 0.0 0.033 14.3 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETS62587.1 - 8.6e-07 28.4 0.0 0.27 10.8 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETS62587.1 - 0.013 15.2 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 0 Kelch motif DUF4366 PF14283.1 ETS62587.1 - 0.07 12.5 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.16 ETS62587.1 - 9.2 6.2 7.5 0.27 11.0 0.7 2.0 2 0 0 2 2 2 0 Gram positive anchor Peptidase_M3 PF01432.15 ETS62588.1 - 4.1e-118 395.3 0.0 5.6e-118 394.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Pol_alpha_B_N PF08418.5 ETS62588.1 - 0.61 9.5 4.0 1.7 8.1 2.7 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal E1-E2_ATPase PF00122.15 ETS62589.1 - 2.6e-19 69.2 0.0 1.9e-18 66.3 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETS62589.1 - 1.2e-16 61.7 0.0 1.9e-15 57.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS62589.1 - 6.9e-12 45.9 0.0 1.6e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS62589.1 - 3.8e-06 26.7 0.0 1.1e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS62589.1 - 0.0083 15.7 0.1 0.02 14.4 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Complex1_LYR PF05347.10 ETS62590.1 - 0.00023 20.8 0.2 0.00053 19.7 0.2 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS62590.1 - 0.0057 16.8 0.3 0.018 15.2 0.1 1.9 2 0 0 2 2 2 1 Complex1_LYR-like zf-C2H2_2 PF12756.2 ETS62591.1 - 2.5e-35 120.6 1.3 1.9e-27 95.3 0.0 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 ETS62591.1 - 1.2e-09 38.0 5.1 4e-09 36.3 1.6 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS62591.1 - 2.9e-09 36.7 18.4 2.5e-08 33.8 3.0 4.5 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 ETS62591.1 - 0.002 17.7 0.5 0.0075 15.9 0.3 2.0 1 0 0 1 1 1 1 DBF zinc finger AKAP95 PF04988.7 ETS62591.1 - 0.022 14.5 0.8 5.8 6.6 0.0 2.5 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 ETS62591.1 - 0.022 14.6 7.5 0.032 14.1 0.6 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETS62591.1 - 0.21 11.9 13.5 6.6 7.3 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS62591.1 - 2.8 8.4 21.3 0.25 11.7 0.3 4.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type Med3 PF11593.3 ETS62591.1 - 2.8 7.0 12.9 4.1 6.5 8.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L40e PF01020.12 ETS62592.1 - 2.3e-31 107.1 9.3 3.6e-31 106.5 6.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 ETS62592.1 - 3.8e-20 71.0 2.6 1.3e-15 56.5 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 ETS62592.1 - 2e-11 43.3 0.4 1.8e-07 30.7 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 ETS62592.1 - 0.022 14.6 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fer2_3 PF13085.1 ETS62592.1 - 0.24 11.2 1.4 0.74 9.6 0.1 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 ETS62592.1 - 0.67 9.3 3.0 0.94 8.8 2.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase EF1G PF00647.14 ETS62593.1 - 8.6e-46 154.0 0.0 1.5e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain CPDase PF07823.6 ETS62593.1 - 1.6e-23 83.2 0.0 2.5e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein GST_N PF02798.15 ETS62593.1 - 7.5e-13 48.4 0.0 1.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS62593.1 - 8.4e-11 41.9 0.0 1.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS62593.1 - 3.8e-10 39.6 0.0 1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS62593.1 - 2.1e-07 30.7 0.0 5.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS62593.1 - 4.4e-07 29.8 0.0 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS62593.1 - 0.00012 22.4 0.0 0.00031 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Thioredoxin PF00085.15 ETS62594.1 - 5e-61 202.8 1.6 1.3e-30 105.0 0.0 4.2 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 ETS62594.1 - 6.1e-39 133.7 0.5 1.8e-28 99.5 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS62594.1 - 9.8e-13 48.0 0.2 0.001 19.1 0.0 4.6 4 1 1 5 5 5 3 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS62594.1 - 3.6e-11 43.2 1.6 0.0008 19.5 0.1 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETS62594.1 - 1.2e-10 41.2 0.0 0.00075 19.4 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 ETS62594.1 - 2.5e-10 39.6 1.0 4.9e-10 38.7 0.7 1.3 1 0 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.16 ETS62594.1 - 7e-07 28.9 0.4 0.052 13.2 0.0 3.1 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_4 PF13462.1 ETS62594.1 - 1.1e-06 28.7 0.9 0.03 14.3 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin Redoxin PF08534.5 ETS62594.1 - 4.1e-05 23.1 3.2 0.013 15.0 0.0 3.2 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 ETS62594.1 - 0.0032 17.2 0.0 0.24 11.2 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Apc1 PF12859.2 ETS62595.1 - 8e-13 48.5 1.2 1.7e-12 47.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 ETS62595.1 - 1.5e-10 40.6 14.1 0.08 13.2 0.0 6.6 6 0 0 6 6 6 5 Proteasome/cyclosome repeat UQ_con PF00179.21 ETS62596.1 - 7e-45 151.9 0.0 9e-45 151.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS62596.1 - 0.048 13.4 0.1 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B CAF1 PF04857.15 ETS62597.1 - 2.5e-65 220.3 0.0 3.7e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease VWA_2 PF13519.1 ETS62598.1 - 6.7e-16 58.8 1.5 7.1e-16 58.7 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 ETS62598.1 - 1.1e-11 43.1 14.3 3.6e-05 22.9 1.0 4.1 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 ETS62598.1 - 5.1e-10 39.2 0.0 7.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 ETS62598.1 - 2.6e-06 27.3 0.1 4.9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain YjeF_N PF03853.10 ETS62598.1 - 0.041 13.5 0.3 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF4362 PF14275.1 ETS62598.1 - 0.085 12.9 0.2 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) MSP1_C PF07462.6 ETS62598.1 - 1.8 6.8 5.9 3.3 5.9 4.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-RanBP PF00641.13 ETS62599.1 - 0.00035 19.6 3.0 0.00071 18.6 2.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RhoGEF PF00621.15 ETS62600.1 - 5e-44 150.3 0.2 1.1e-43 149.2 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 ETS62600.1 - 7.8e-41 138.9 0.0 1.8e-40 137.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 ETS62600.1 - 3.4e-34 116.7 0.1 6.2e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 ETS62600.1 - 4.4e-08 32.6 0.0 1.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 ETS62600.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 PH domain DNA_ligase_A_N PF04675.9 ETS62602.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA ligase N terminus V_ATPase_I PF01496.14 ETS62603.1 - 0.54 8.0 12.8 0.59 7.9 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Caldesmon PF02029.10 ETS62603.1 - 1.1 7.6 22.7 1.6 7.0 15.7 1.3 1 0 0 1 1 1 0 Caldesmon DUF572 PF04502.8 ETS62603.1 - 3.2 6.9 22.0 3.5 6.7 15.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOBP PF15279.1 ETS62603.1 - 3.3 7.9 14.0 4 7.7 9.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Fasciclin PF02469.17 ETS62603.1 - 4.8 7.2 11.6 1.6 8.7 5.0 2.0 1 1 1 2 2 2 0 Fasciclin domain Borrelia_P83 PF05262.6 ETS62603.1 - 7.5 4.6 32.8 8.8 4.4 22.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2203 PF09969.4 ETS62603.1 - 7.6 6.7 10.6 7.2 6.8 6.3 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ASF1_hist_chap PF04729.8 ETS62604.1 - 2.7e-66 221.9 0.1 3.1e-66 221.7 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Dus PF01207.12 ETS62605.1 - 2.5e-41 141.5 0.0 1.2e-21 76.8 0.0 3.1 2 1 1 3 3 3 3 Dihydrouridine synthase (Dus) Zn_clus PF00172.13 ETS62607.1 - 5.6e-09 35.7 11.4 1e-08 34.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSG PF02349.10 ETS62607.1 - 0.33 10.9 9.3 0.51 10.3 6.5 1.2 1 0 0 1 1 1 0 Major surface glycoprotein eIF-5a PF01287.15 ETS62608.1 - 1.4e-27 95.4 0.2 2.1e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 ETS62608.1 - 0.00022 20.8 0.5 0.00044 19.8 0.4 1.5 1 0 0 1 1 1 1 KOW motif HLH PF00010.21 ETS62609.1 - 1.1e-12 47.4 0.3 2.1e-12 46.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhaP_Bmeg PF09602.5 ETS62609.1 - 0.038 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1620 PF07774.8 ETS62610.1 - 1.3e-56 191.2 0.0 2e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 ETS62610.1 - 1.4e-09 37.8 5.1 4.6e-06 26.2 0.6 3.7 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 ETS62610.1 - 1.8e-05 24.0 0.2 1.3 8.6 0.0 4.9 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.1 ETS62610.1 - 0.7 10.2 6.6 3.6 7.9 0.0 5.2 6 0 0 6 6 6 0 PQQ-like domain Zn_clus PF00172.13 ETS62611.1 - 9.1e-09 35.0 10.8 1.6e-08 34.2 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS62611.1 - 7.4e-07 28.3 0.0 1.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpb2_6 PF00562.23 ETS62612.1 - 3e-112 375.1 0.1 3.5e-112 374.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 ETS62612.1 - 3.1e-28 97.8 0.1 6.5e-28 96.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.10 ETS62613.1 - 2.1e-60 203.1 0.2 5.6e-60 201.7 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 ETS62613.1 - 3e-36 124.6 0.3 6.3e-36 123.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 ETS62613.1 - 1.2e-24 85.9 2.5 5.9e-24 83.6 0.5 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 ETS62613.1 - 5.7e-21 74.0 0.0 1.5e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 ETS62613.1 - 2.1e-12 46.7 0.4 1.7e-11 43.9 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Metallophos PF00149.23 ETS62614.1 - 2.2e-42 144.7 0.1 2.8e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RrnaAD PF00398.15 ETS62615.1 - 6.2e-56 189.3 0.0 8.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 ETS62615.1 - 7.6e-09 35.6 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS62615.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 ETS62615.1 - 0.00078 19.9 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS62615.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 ETS62615.1 - 0.0036 16.5 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 ETS62615.1 - 0.0039 17.6 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS62615.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS62615.1 - 0.0091 15.1 0.0 0.022 13.8 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 ETS62615.1 - 0.0095 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 ETS62615.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 ETS62615.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 ETS62615.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.15 ETS62616.1 - 9.7e-151 502.6 5.6 1.3e-150 502.2 3.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETS62616.1 - 5.2e-27 94.8 0.9 4.4e-24 85.2 0.0 3.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETS62616.1 - 2.9e-17 62.7 6.5 1e-05 25.7 0.0 5.6 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 ETS62616.1 - 4.3e-10 38.8 0.3 0.0087 16.0 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 ETS62616.1 - 2.6e-06 27.7 2.7 0.031 14.7 0.0 6.3 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 ETS62616.1 - 0.00096 18.5 0.0 2.1 7.6 0.0 3.0 3 0 0 3 3 3 2 CLASP N terminal Lyase_1 PF00206.15 ETS62617.1 - 2.7e-23 82.6 0.0 4.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 ETS62617.1 - 5e-16 58.4 0.0 1.1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Adaptin_binding PF10199.4 ETS62618.1 - 2.3e-25 89.4 0.0 8.6e-25 87.6 0.0 2.0 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Sod_Fe_C PF02777.13 ETS62619.1 - 8.3e-36 122.0 0.1 1.4e-35 121.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETS62619.1 - 4.5e-32 110.1 3.7 7.3e-32 109.4 2.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Mus7 PF09462.5 ETS62620.1 - 6.9e-157 523.9 0.0 9e-157 523.5 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4140 PF13600.1 ETS62621.1 - 1.4 9.4 5.9 16 5.9 0.7 3.3 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) tRNA-synt_His PF13393.1 ETS62621.1 - 1.4 7.9 6.4 1 8.3 0.3 2.4 2 1 1 3 3 3 0 Histidyl-tRNA synthetase HisKA_3 PF07730.8 ETS62621.1 - 5.5 7.4 6.5 6.2 7.2 0.0 3.3 4 0 0 4 4 4 0 Histidine kinase Membr_traf_MHD PF10540.4 ETS62622.1 - 3e-18 65.9 0.5 1.8e-16 60.1 0.1 2.9 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 ETS62622.1 - 1.2e-07 31.4 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Nucleos_tra2_C PF07662.8 ETS62622.1 - 0.068 12.6 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus ATP-synt_E PF05680.7 ETS62622.1 - 3.2 7.7 9.3 1.5 8.8 0.0 3.4 3 0 0 3 3 3 0 ATP synthase E chain Aa_trans PF01490.13 ETS62624.1 - 2e-18 66.1 39.2 2.7e-18 65.6 27.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein F-box-like PF12937.2 ETS62625.1 - 2.4e-11 43.1 0.1 5.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF3506 PF12014.3 ETS62625.1 - 8.2e-09 35.3 0.0 2.8e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box PF00646.28 ETS62625.1 - 0.00016 21.2 0.0 0.0004 19.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain Ras PF00071.17 ETS62626.1 - 5.4e-59 198.1 0.1 6.4e-59 197.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS62626.1 - 1.8e-19 70.3 0.0 3.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS62626.1 - 1e-12 47.6 0.0 1.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS62626.1 - 2.8e-07 30.1 0.0 5.3e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS62626.1 - 1.7e-06 27.3 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS62626.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GSK-3_bind PF05350.7 ETS62626.1 - 0.0032 16.9 0.2 0.0054 16.2 0.2 1.3 1 0 0 1 1 1 1 Glycogen synthase kinase-3 binding AAA_22 PF13401.1 ETS62626.1 - 0.0053 16.8 0.1 0.98 9.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS62626.1 - 0.033 14.1 1.2 0.16 11.9 0.8 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 ETS62626.1 - 0.043 13.0 0.1 0.12 11.5 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function, DUF258 TCP PF03634.8 ETS62626.1 - 0.043 14.1 0.3 0.064 13.6 0.2 1.2 1 0 0 1 1 1 0 TCP family transcription factor SRPRB PF09439.5 ETS62626.1 - 0.087 12.0 0.1 0.27 10.4 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NIF3 PF01784.13 ETS62627.1 - 9.4e-63 212.0 0.0 1.1e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COPIIcoated_ERV PF07970.7 ETS62628.1 - 4.8e-38 130.9 0.0 7.7e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 ETS62628.1 - 1.8e-23 82.2 0.1 3.5e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RNA_pol_A_bac PF01000.21 ETS62629.1 - 3.3e-28 98.0 0.0 5.8e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 ETS62629.1 - 7.1e-16 57.0 0.0 1.1e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_C65 PF10275.4 ETS62630.1 - 2.6e-72 243.0 0.0 3.1e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 ETS62630.1 - 0.0009 19.8 0.0 0.015 15.9 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease Fungal_trans PF04082.13 ETS62631.1 - 1.8e-15 56.5 0.1 3.5e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS62631.1 - 3.6e-05 23.5 11.0 5.5e-05 22.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_dim PF02852.17 ETS62632.1 - 4.6e-42 142.5 1.5 7.5e-42 141.8 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 ETS62632.1 - 9.7e-39 133.3 13.0 1.5e-28 100.0 2.9 3.5 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS62632.1 - 4.1e-19 68.7 9.2 4.6e-16 59.0 1.4 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS62632.1 - 3.3e-11 42.9 4.3 9.9e-11 41.3 0.2 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS62632.1 - 7.2e-10 39.2 4.7 5e-05 23.4 1.1 3.3 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS62632.1 - 2e-08 33.5 8.4 8.3e-07 28.1 2.7 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 ETS62632.1 - 1.3e-07 30.9 3.2 0.00044 19.4 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 ETS62632.1 - 3e-07 29.6 2.3 3e-07 29.6 1.6 3.7 3 1 1 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.1 ETS62632.1 - 4e-07 29.9 4.9 0.00034 20.5 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS62632.1 - 1.3e-06 27.1 13.1 0.00039 19.0 0.6 4.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 ETS62632.1 - 1.5e-05 24.2 8.6 0.049 12.6 0.0 3.3 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 ETS62632.1 - 1.9e-05 23.7 0.4 0.11 11.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS62632.1 - 9.1e-05 21.5 12.4 0.0057 15.5 0.1 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS62632.1 - 0.00018 21.1 3.5 0.056 13.0 0.1 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 ETS62632.1 - 0.97 8.2 7.4 0.68 8.7 0.5 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 ETS62632.1 - 4.4 6.9 9.6 0.099 12.2 0.7 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UQ_con PF00179.21 ETS62633.1 - 1.8e-34 118.1 0.0 2.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L18ae PF01775.12 ETS62634.1 - 7.4e-59 197.0 2.0 9.3e-59 196.7 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain RRM_6 PF14259.1 ETS62635.1 - 3.2e-10 39.8 0.0 2.4e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 ETS62635.1 - 9.4e-07 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 ETS62635.1 - 1e-06 28.4 0.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 ETS62635.1 - 1.5e-06 27.7 4.1 2.7e-06 26.9 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 ETS62635.1 - 2.1e-06 27.4 0.1 7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS62635.1 - 4.9e-05 22.8 0.1 0.32 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Seryl_tRNA_N PF02403.17 ETS62635.1 - 0.28 11.1 14.6 0.035 14.1 4.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COX5A PF02284.11 ETS62636.1 - 2.6e-39 133.5 0.1 3.7e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Adap_comp_sub PF00928.16 ETS62637.1 - 2.2e-20 72.8 0.0 3.4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETS62637.1 - 2.6e-05 23.9 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain U79_P34 PF03064.11 ETS62637.1 - 0.14 11.6 3.3 5.7 6.3 0.2 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 TT_ORF2 PF02957.10 ETS62637.1 - 0.18 12.4 1.0 0.33 11.6 0.1 1.8 1 1 1 2 2 2 0 TT viral ORF2 RRM_1 PF00076.17 ETS62640.1 - 1.6e-18 66.0 0.3 1.2e-09 37.6 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS62640.1 - 6.3e-16 57.9 0.0 6.6e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS62640.1 - 9.1e-11 41.5 0.1 3.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS62640.1 - 0.0013 18.5 0.1 0.071 12.8 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 ETS62642.1 - 2.1e-22 78.5 0.0 2.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS62642.1 - 3e-18 65.5 0.0 5.2e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS62642.1 - 4.5e-11 42.4 0.0 9.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS62642.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Limkain-b1 PF11608.3 ETS62642.1 - 0.086 12.6 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 GRP PF07172.6 ETS62642.1 - 2.9 8.4 10.4 6.4 7.3 7.2 1.6 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.17 ETS62643.1 - 1.9e-12 46.6 0.0 3.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS62643.1 - 6.6e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS62643.1 - 7.5e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS62643.1 - 0.0031 17.2 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SET PF00856.23 ETS62644.1 - 2.1e-12 47.6 0.0 1.9e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 ETS62644.1 - 0.023 14.5 6.1 0.023 14.5 4.2 1.8 2 0 0 2 2 2 0 MYND finger NST1 PF13945.1 ETS62645.1 - 1e-47 162.6 10.1 1e-47 162.6 7.0 5.9 3 2 1 4 4 4 2 Salt tolerance down-regulator BRF1 PF07741.8 ETS62645.1 - 0.85 9.8 0.0 0.85 9.8 0.0 7.1 4 1 1 5 5 5 0 Brf1-like TBP-binding domain SPX PF03105.14 ETS62645.1 - 5.2 6.7 0.0 5.2 6.7 0.0 3.8 2 1 1 3 3 3 0 SPX domain DUF3639 PF12341.3 ETS62647.1 - 0.13 12.2 0.5 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) Mid1 PF12929.2 ETS62648.1 - 1.1e-70 238.5 3.8 1.4e-70 238.1 2.6 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component fn3 PF00041.16 ETS62648.1 - 0.036 14.1 1.0 0.27 11.4 0.0 2.6 3 0 0 3 3 3 0 Fibronectin type III domain Fz PF01392.17 ETS62648.1 - 0.08 13.3 2.8 0.19 12.0 0.2 2.3 2 0 0 2 2 2 0 Fz domain ABC1 PF03109.11 ETS62649.1 - 1.1e-29 102.8 0.0 2e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.4 ETS62649.1 - 2.3e-18 65.3 0.2 2.3e-18 65.3 0.1 2.4 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal PPV_E2_C PF00511.12 ETS62649.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 E2 (early) protein, C terminal Lipase_3 PF01764.20 ETS62650.1 - 3.1e-16 59.2 0.0 4.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 ETS62650.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 ETS62650.1 - 0.05 13.0 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) MFS_1 PF07690.11 ETS62651.1 - 5.3e-25 87.8 44.2 5.3e-25 87.8 30.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Gp_dh_C PF02800.15 ETS62652.1 - 8.9e-76 252.6 0.0 1.3e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 ETS62652.1 - 1.6e-58 196.9 0.5 2.6e-58 196.2 0.3 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TauD PF02668.11 ETS62653.1 - 8.1e-29 101.0 0.0 1.7e-28 100.0 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RNA_pol PF00940.14 ETS62654.1 - 2.2e-157 523.6 0.0 3.3e-157 523.1 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 ETS62654.1 - 1.1e-82 277.8 2.8 1.8e-82 277.1 2.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 ETS62654.1 - 0.0014 18.5 0.0 0.064 13.2 0.0 2.8 2 1 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 ETS62654.1 - 0.014 15.6 1.5 6.4 7.3 0.1 4.4 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Ras PF00071.17 ETS62655.1 - 2.1e-50 170.3 0.0 2.4e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS62655.1 - 4.1e-17 62.7 0.0 5.7e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS62655.1 - 3.5e-06 26.3 0.0 5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS62655.1 - 0.021 14.2 0.0 0.089 12.2 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 ETS62655.1 - 0.032 13.7 0.0 4.2 6.8 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 ETS62655.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PCI PF01399.22 ETS62656.1 - 1.3e-10 41.5 0.1 4.1e-10 39.9 0.0 1.9 2 1 0 2 2 2 1 PCI domain Amidohydro_3 PF07969.6 ETS62657.1 - 2.7e-65 221.1 3.8 3.8e-65 220.6 2.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Methyltransf_18 PF12847.2 ETS62657.1 - 2e-09 38.0 0.0 6.7e-09 36.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS62657.1 - 2.1e-09 37.3 0.0 5.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS62657.1 - 5.5e-09 35.7 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS62657.1 - 3e-08 34.0 0.0 5.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS62657.1 - 7.5e-06 26.3 0.0 1.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS62657.1 - 8.3e-06 26.1 0.0 2.2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS62657.1 - 1.3e-05 25.1 0.1 3.8e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 ETS62657.1 - 0.00011 22.9 0.0 0.00035 21.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS62657.1 - 0.00016 21.1 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Amidohydro_1 PF01979.15 ETS62657.1 - 0.00084 19.0 0.1 0.0034 17.0 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family CMAS PF02353.15 ETS62657.1 - 0.014 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Amidohydro_5 PF13594.1 ETS62657.1 - 0.017 14.9 0.2 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Amidohydrolase Methyltransf_16 PF10294.4 ETS62657.1 - 0.023 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 ETS62657.1 - 0.041 12.9 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 ETS62657.1 - 0.12 11.4 0.0 0.3 10.1 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 ETS62657.1 - 0.44 9.6 0.0 0.79 8.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1289 PF06945.8 ETS62658.1 - 0.048 13.1 0.2 0.072 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) FA_desaturase PF00487.19 ETS62659.1 - 2e-30 106.1 26.4 4.5e-30 104.9 18.3 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 ETS62659.1 - 2.3e-12 46.5 0.0 5.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_6 PF12697.2 ETS62660.1 - 8.6e-16 58.4 1.5 1.9e-15 57.3 0.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS62660.1 - 2.4e-10 40.3 0.0 5.4e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS62660.1 - 0.00085 19.1 0.0 0.013 15.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 ETS62661.1 - 3e-18 64.9 1.2 2.9e-08 33.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 ETS62661.1 - 0.00061 19.2 0.0 0.042 13.3 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 ETS62661.1 - 0.038 13.6 0.4 1.4 8.6 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 ETS62661.1 - 0.044 12.8 0.1 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal MFS_1 PF07690.11 ETS62662.1 - 2.9e-19 68.9 33.4 2.9e-19 68.9 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 ETS62662.1 - 7.6e-15 54.7 8.0 2.3e-14 53.1 5.6 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 TUDOR PF00567.19 ETS62663.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Tudor domain Abhydrolase_3 PF07859.8 ETS62664.1 - 1.2e-48 165.4 0.0 1.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS62664.1 - 9.1e-08 31.2 3.4 5.7e-07 28.6 2.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS62664.1 - 2.5e-05 24.0 0.2 3.5e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 ETS62664.1 - 0.00033 19.9 0.1 0.00055 19.2 0.0 1.3 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Peptidase_S9 PF00326.16 ETS62664.1 - 0.00052 19.3 0.3 0.048 12.8 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 ETS62664.1 - 0.00067 18.2 0.0 0.014 13.9 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 ETS62664.1 - 0.0018 18.1 1.7 0.0042 16.9 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS62664.1 - 0.065 11.8 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF4499 PF14934.1 ETS62665.1 - 0.0073 16.2 0.8 0.018 14.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) DUF1929 PF09118.6 ETS62666.1 - 1.3e-13 50.8 0.2 2.4e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_1 PF01344.20 ETS62666.1 - 1.2e-07 31.1 1.1 8e-06 25.3 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 ETS62666.1 - 0.0034 17.5 5.9 0.023 14.8 0.0 3.8 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 ETS62666.1 - 0.004 16.8 0.1 0.004 16.8 0.1 3.6 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 ETS62666.1 - 0.0058 16.7 0.2 0.19 11.9 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Sugar_tr PF00083.19 ETS62667.1 - 2.7e-103 345.9 25.8 3.1e-103 345.7 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS62667.1 - 5.7e-20 71.3 36.3 2.6e-19 69.1 5.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.17 ETS62668.1 - 9e-35 119.6 0.0 1.1e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.13 ETS62669.1 - 1.1e-09 37.9 6.3 1.9e-09 37.2 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS62669.1 - 8.5e-09 34.6 0.0 1.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BioT2 PF15368.1 ETS62669.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis family BioT2 NAD_binding_10 PF13460.1 ETS62670.1 - 6.4e-05 23.0 0.0 9.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETS62670.1 - 0.086 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 ETS62670.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 ETS62670.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Tannase PF07519.6 ETS62672.1 - 7.5e-112 374.4 0.7 9.2e-112 374.1 0.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 ETS62672.1 - 0.09 11.9 1.6 2.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pollen_allerg_2 PF01620.11 ETS62672.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Glyco_hydro_11 PF00457.12 ETS62673.1 - 5.7e-58 195.2 18.0 6.6e-58 195.0 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 HopJ PF08888.6 ETS62673.1 - 0.092 12.7 0.5 0.21 11.6 0.4 1.7 1 0 0 1 1 1 0 HopJ type III effector protein Dynactin_p62 PF05502.8 ETS62675.1 - 1.3e-125 419.9 9.5 2.3e-125 419.1 6.6 1.4 1 0 0 1 1 1 1 Dynactin p62 family SDA1 PF05285.7 ETS62675.1 - 0.13 11.5 13.4 0.49 9.6 4.7 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 ETS62675.1 - 0.69 7.7 11.6 1 7.1 8.1 1.2 1 0 0 1 1 1 0 Nop14-like family UPF0547 PF10571.4 ETS62675.1 - 7.5 6.3 17.2 1 9.1 0.2 3.7 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 Nucleoplasmin PF03066.10 ETS62675.1 - 9.2 5.7 7.1 16 4.9 5.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin polyprenyl_synt PF00348.12 ETS62676.1 - 1.8e-73 246.6 0.0 2.2e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Rsa3 PF14615.1 ETS62677.1 - 2.4e-07 29.9 0.1 9.8e-07 27.9 0.0 2.1 2 1 0 2 2 2 1 Ribosome-assembly protein 3 AMPKBI PF04739.10 ETS62677.1 - 0.056 13.2 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain DUF2026 PF09641.5 ETS62677.1 - 0.39 10.0 2.1 2.6 7.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) DUF605 PF04652.11 ETS62677.1 - 5.9 6.1 39.4 11 5.3 27.3 1.4 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 ETS62678.1 - 5.2e-24 84.5 0.1 9.2e-24 83.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS62678.1 - 6.7e-09 35.5 7.8 0.0003 20.9 2.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS62678.1 - 4.8e-07 29.6 7.3 0.0027 17.9 2.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS62678.1 - 0.00047 20.3 2.5 0.28 11.5 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-BED PF02892.10 ETS62678.1 - 0.00094 18.8 1.1 0.00094 18.8 0.7 2.1 2 0 0 2 2 2 1 BED zinc finger zf-Di19 PF05605.7 ETS62678.1 - 0.0062 16.6 0.7 0.013 15.5 0.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 ETS62678.1 - 0.3 11.2 5.4 1.4 9.1 1.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS62678.1 - 2.3 8.2 4.8 22 5.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Epimerase PF01370.16 ETS62679.1 - 1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS62679.1 - 5.7e-06 25.2 0.0 7.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS62679.1 - 8.8e-06 24.8 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETS62679.1 - 1.2e-05 24.4 0.0 0.00054 18.9 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETS62679.1 - 0.00033 20.6 0.0 0.00077 19.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS62679.1 - 0.051 12.4 0.0 0.33 9.7 0.0 2.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 ETS62680.1 - 1.1e-34 119.6 28.4 1.3e-34 119.4 18.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 ETS62680.1 - 0.0098 15.0 3.4 0.67 9.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1616) MerC PF03203.9 ETS62680.1 - 0.85 10.0 7.3 0.094 13.0 1.2 2.4 2 2 0 2 2 2 0 MerC mercury resistance protein Pkinase PF00069.20 ETS62681.1 - 1.8e-52 178.0 0.0 2.2e-46 158.1 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62681.1 - 2.4e-26 92.3 0.7 1.4e-21 76.7 0.0 3.5 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.1 ETS62681.1 - 4.7e-05 22.4 0.0 0.19 10.6 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Keratin PF02422.11 ETS62682.1 - 0.017 15.0 0.8 0.017 15.0 0.6 1.6 1 1 0 1 1 1 0 Keratin Cyto_heme_lyase PF01265.12 ETS62683.1 - 1.3e-70 237.9 0.3 3e-70 236.7 0.1 1.6 1 1 1 2 2 2 1 Cytochrome c/c1 heme lyase DUF607 PF04678.8 ETS62684.1 - 1.3e-42 145.8 0.1 3.4e-42 144.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF607 UbiA PF01040.13 ETS62684.1 - 1e-29 103.5 17.9 1e-29 103.5 12.4 2.2 2 1 0 2 2 2 1 UbiA prenyltransferase family Brr6_like_C_C PF10104.4 ETS62686.1 - 7.9e-42 141.9 0.2 1e-41 141.6 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.1 ETS62686.1 - 0.11 12.8 1.6 0.32 11.3 1.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Y_phosphatase2 PF03162.8 ETS62687.1 - 1.3e-24 86.4 0.0 5.6e-23 81.1 0.0 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Nucleo_P87 PF07267.6 ETS62687.1 - 0.017 13.8 7.0 0.025 13.2 4.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Y_phosphatase PF00102.22 ETS62687.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AIP3 PF03915.8 ETS62688.1 - 1.7e-108 363.2 2.0 3.2e-108 362.3 1.4 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 DUF2315 PF10231.4 ETS62688.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Fib_alpha PF08702.5 ETS62688.1 - 1.1 9.3 7.9 28 4.7 0.2 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF383 PF04063.9 ETS62689.1 - 3.8e-77 258.1 0.0 6.9e-77 257.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 ETS62689.1 - 4.3e-19 67.8 0.1 8.2e-19 66.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.17 ETS62689.1 - 0.026 14.5 0.8 0.33 11.1 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat ScpA_ScpB PF02616.9 ETS62689.1 - 1.1 8.7 5.1 0.78 9.2 0.5 2.2 2 0 0 2 2 2 0 ScpA/B protein Zn_clus PF00172.13 ETS62690.1 - 1.6e-09 37.4 10.2 3.9e-09 36.2 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS62690.1 - 0.00049 19.0 0.2 0.00094 18.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box PF00505.14 ETS62691.1 - 7.1e-10 39.0 4.4 9.1e-09 35.4 3.0 2.5 1 1 0 1 1 1 1 HMG (high mobility group) box DNA_pol_B PF00136.16 ETS62693.1 - 1.5e-147 492.1 2.7 2.2e-147 491.6 1.9 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 ETS62693.1 - 1.3e-90 303.5 0.0 2.3e-90 302.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 ETS62693.1 - 3.1e-23 81.5 7.4 7.4e-23 80.3 5.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 ETS62693.1 - 0.0013 17.4 0.9 0.01 14.5 0.0 2.5 2 1 0 3 3 3 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 ETS62693.1 - 0.019 14.7 0.2 0.079 12.7 0.1 2.2 1 1 0 1 1 1 0 RNase_H superfamily zf-RING-like PF08746.6 ETS62693.1 - 3.6 7.6 9.6 0.077 13.0 0.8 2.6 2 0 0 2 2 2 0 RING-like domain AMP-binding PF00501.23 ETS62694.1 - 1.3e-81 274.1 0.0 1.6e-81 273.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS62694.1 - 2.2e-12 47.7 0.1 8.8e-12 45.8 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 ETS62694.1 - 0.0013 17.3 0.0 0.14 10.6 0.0 2.2 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Nol1_Nop2_Fmu PF01189.12 ETS62695.1 - 1.6e-94 316.4 0.0 2e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 ETS62695.1 - 2.8e-05 23.7 0.0 0.00011 21.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 ETS62695.1 - 0.0003 20.4 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 ETS62695.1 - 0.00098 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 ETS62695.1 - 0.003 17.1 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 ETS62695.1 - 0.021 15.3 0.1 0.091 13.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 ETS62695.1 - 0.036 13.4 0.0 0.5 9.7 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain Sigma70_ner PF04546.8 ETS62695.1 - 0.04 13.5 0.1 0.04 13.5 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF938 PF06080.7 ETS62695.1 - 0.049 13.1 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Acyl-CoA_dh_1 PF00441.19 ETS62696.1 - 1.1e-31 109.9 0.3 1.9e-31 109.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS62696.1 - 6.3e-17 60.8 3.2 3.1e-16 58.6 0.6 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 ETS62696.1 - 3e-16 58.9 0.0 6.9e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 ETS62696.1 - 4.1e-11 43.4 0.0 5.1e-10 39.9 0.0 2.8 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS62696.1 - 1.2e-06 28.8 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 ETS62696.1 - 0.1 11.9 0.1 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal EIF_2_alpha PF07541.7 ETS62697.1 - 1.9e-41 140.3 0.3 4.1e-41 139.2 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 ETS62697.1 - 1.2e-13 50.8 1.2 2.8e-13 49.7 0.3 2.1 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 ETS62697.1 - 0.0085 16.0 0.1 0.022 14.6 0.1 1.9 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 NRDE-2 PF08424.5 ETS62698.1 - 1.3e-29 103.1 0.0 3.5e-28 98.4 0.0 2.4 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference Ank_2 PF12796.2 ETS62698.1 - 1e-05 25.7 0.0 3.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS62698.1 - 1.5e-05 24.5 0.4 0.0048 16.6 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 ETS62698.1 - 4.1e-05 23.9 0.1 0.00016 22.0 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS62698.1 - 0.00014 21.9 2.0 0.029 14.6 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS62698.1 - 0.0032 17.5 0.1 5.3 7.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Carn_acyltransf PF00755.15 ETS62701.1 - 4.2e-137 457.7 0.0 7.1e-137 456.9 0.0 1.4 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase RabGAP-TBC PF00566.13 ETS62702.1 - 6.4e-52 176.1 0.0 9.3e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CPSF73-100_C PF11718.3 ETS62703.1 - 3.4e-46 157.3 0.6 1.5e-45 155.1 0.3 2.1 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 ETS62703.1 - 7.7e-30 103.4 0.0 1.7e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 ETS62703.1 - 1e-17 64.4 1.2 2.1e-17 63.4 0.8 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS62703.1 - 5.1e-11 42.4 1.9 5.1e-11 42.4 1.3 2.5 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 ETS62703.1 - 1.2e-10 40.9 0.2 2.3e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 ETS62703.1 - 1.5e-07 31.3 1.5 1.9e-07 30.9 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain MRP_L53 PF10780.4 ETS62704.1 - 0.028 14.3 0.3 0.068 13.1 0.2 1.8 1 1 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 DUF2454 PF10521.4 ETS62705.1 - 5e-09 35.5 0.0 4.8e-08 32.3 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) tRNA-synt_1d PF00750.14 ETS62706.1 - 2.6e-84 283.0 1.6 3.4e-84 282.6 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 ETS62706.1 - 4.8e-22 78.1 0.0 1.5e-21 76.5 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain ArabFuran-catal PF09206.6 ETS62708.1 - 1.6e-137 457.7 21.0 1.9e-137 457.6 14.5 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic F-box-like PF12937.2 ETS62709.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.9 1 1 0 1 1 1 0 F-box-like Spc97_Spc98 PF04130.8 ETS62710.1 - 2.2e-109 366.2 0.0 2.8e-109 365.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DEK_C PF08766.6 ETS62711.1 - 3.6e-06 26.6 0.5 1.3e-05 24.8 0.4 2.0 1 1 0 1 1 1 1 DEK C terminal domain DUF605 PF04652.11 ETS62711.1 - 1.7 7.9 25.6 0.023 14.0 8.2 2.1 2 0 0 2 2 2 0 Vta1 like Sugar_tr PF00083.19 ETS62712.1 - 2.4e-97 326.3 22.2 2.8e-97 326.1 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS62712.1 - 1.2e-20 73.5 27.5 3.4e-20 72.0 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_hydroxylase PF04116.8 ETS62713.1 - 1.5e-14 54.3 18.0 1.5e-14 54.3 12.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M16 PF00675.15 ETS62714.1 - 2.3e-23 82.6 2.1 1.5e-22 79.9 0.2 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 ETS62714.1 - 4.3e-13 49.3 0.1 2.4e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Sad1_UNC PF07738.8 ETS62715.1 - 1.9e-08 34.1 0.0 7.5e-06 25.7 0.0 2.3 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Phage_min_cap2 PF06152.6 ETS62715.1 - 0.01 14.8 1.9 0.016 14.1 1.3 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 PBP1_TM PF14812.1 ETS62715.1 - 0.45 10.8 15.0 1.4 9.2 1.2 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fib_alpha PF08702.5 ETS62715.1 - 2.9 7.9 5.7 6.8 6.7 3.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ATP_bind_1 PF03029.12 ETS62716.1 - 1.2e-74 250.8 0.4 5.5e-68 229.0 0.0 2.7 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 ETS62716.1 - 1.5e-05 24.4 0.4 7.7e-05 22.2 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 ETS62716.1 - 5.5e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 ETS62716.1 - 0.00056 19.9 0.0 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS62716.1 - 0.0027 17.8 0.0 0.0088 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS62716.1 - 0.0045 17.8 0.0 0.013 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 ETS62716.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS62716.1 - 0.0061 15.8 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.7 ETS62716.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 ETS62716.1 - 0.025 14.0 0.3 0.27 10.5 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS62716.1 - 0.025 14.0 0.1 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 ETS62716.1 - 0.028 13.2 0.0 0.46 9.2 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_33 PF13671.1 ETS62716.1 - 0.039 13.8 0.2 0.039 13.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS62716.1 - 0.044 14.1 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 ETS62716.1 - 0.054 13.2 0.5 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 G-alpha PF00503.15 ETS62716.1 - 0.09 11.4 0.0 2.6 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit SRP54 PF00448.17 ETS62716.1 - 0.1 12.0 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 ETS62716.1 - 0.1 12.7 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 ETS62716.1 - 0.13 11.6 0.0 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.5 ETS62716.1 - 0.23 10.6 0.0 0.44 9.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PPV_E1_C PF00519.12 ETS62716.1 - 0.23 10.0 0.0 0.36 9.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Septin PF00735.13 ETS62716.1 - 0.23 10.4 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Septin Zn_clus PF00172.13 ETS62717.1 - 6.8e-07 29.0 9.7 1.2e-06 28.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UMP1 PF05348.6 ETS62718.1 - 6.7e-22 77.8 0.1 8.1e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 rRNA_proc-arch PF13234.1 ETS62719.1 - 3.2e-95 318.3 0.0 4.7e-95 317.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 ETS62719.1 - 1.5e-58 197.0 0.9 1.5e-58 197.0 0.6 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 ETS62719.1 - 8.1e-22 77.4 0.0 4.8e-21 74.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS62719.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 ETS62719.1 - 0.032 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain CENP-F_leu_zip PF10473.4 ETS62719.1 - 0.12 12.2 4.7 0.096 12.5 0.3 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAMP PF00672.20 ETS62719.1 - 0.13 12.4 1.0 8.4 6.6 0.1 2.6 2 0 0 2 2 2 0 HAMP domain DUF1510 PF07423.6 ETS62719.1 - 0.61 9.4 6.9 1.4 8.2 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) 5_nucleotid_C PF02872.13 ETS62720.1 - 6.4e-27 94.4 0.0 8.7e-21 74.5 0.0 2.5 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 ETS62720.1 - 4.5e-10 39.2 0.2 1.7e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS62720.1 - 0.0012 18.6 0.1 0.0048 16.7 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Syntaxin-6_N PF09177.6 ETS62721.1 - 8.2e-22 77.4 1.3 5.6e-21 74.7 0.0 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 ETS62721.1 - 2.5e-11 43.0 6.4 6.1e-11 41.8 2.0 2.6 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 ETS62721.1 - 0.0063 15.9 0.1 0.023 14.1 0.1 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 Syntaxin PF00804.20 ETS62721.1 - 0.02 15.0 1.6 0.65 10.1 0.0 2.6 2 1 0 2 2 2 0 Syntaxin IFT57 PF10498.4 ETS62721.1 - 0.032 12.9 0.1 0.37 9.4 0.0 2.0 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 Calpain_inhib PF00748.14 ETS62721.1 - 0.05 13.9 0.4 0.1 12.9 0.3 1.5 1 0 0 1 1 1 0 Calpain inhibitor PEP-utilisers_N PF05524.8 ETS62721.1 - 0.051 13.3 2.3 2.1 8.1 1.1 3.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal WXG100 PF06013.7 ETS62721.1 - 0.059 13.3 2.9 4.9 7.2 0.0 3.6 3 2 0 3 3 3 0 Proteins of 100 residues with WXG HisKA_3 PF07730.8 ETS62721.1 - 0.067 13.5 2.1 5.9 7.3 0.3 2.8 2 1 0 2 2 2 0 Histidine kinase DUF1664 PF07889.7 ETS62721.1 - 0.18 11.5 2.2 7.2 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 ETS62721.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.5 2 1 0 2 2 2 0 FlxA-like protein FlaC_arch PF05377.6 ETS62721.1 - 0.51 10.2 2.8 3.8 7.4 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.10 ETS62721.1 - 0.95 9.6 5.0 7.1 6.8 0.0 3.6 3 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF883 PF05957.8 ETS62721.1 - 1.5 9.3 5.0 6.8 7.1 1.0 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PPTA PF01239.17 ETS62723.1 - 2.4e-30 102.6 17.3 3.4e-07 29.3 0.2 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 ETS62723.1 - 0.00096 19.1 0.3 0.29 11.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3136 PF11334.3 ETS62723.1 - 0.045 13.1 0.1 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) BolA PF01722.13 ETS62724.1 - 9.8e-26 89.5 0.3 2.1e-25 88.4 0.2 1.5 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L9_N PF01281.14 ETS62724.1 - 1.4e-10 40.1 0.0 3.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain polyprenyl_synt PF00348.12 ETS62725.1 - 2.3e-39 134.7 1.2 2e-20 72.7 0.1 4.1 3 1 0 3 3 3 3 Polyprenyl synthetase DUF718 PF05336.8 ETS62726.1 - 2.1e-16 59.6 0.0 3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF718) CD99L2 PF12301.3 ETS62727.1 - 0.12 12.1 2.2 0.12 12.1 0.8 1.5 1 1 1 2 2 2 0 CD99 antigen like protein 2 Pkinase PF00069.20 ETS62728.1 - 4e-59 199.8 0.0 8.2e-39 133.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62728.1 - 8.2e-26 90.6 0.0 3.3e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 ETS62728.1 - 4.5e-09 36.3 0.0 9.5e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 ETS62728.1 - 1.1e-07 31.1 0.2 6.2e-06 25.3 0.0 2.6 3 0 0 3 3 3 1 Kinase-like PAS_9 PF13426.1 ETS62728.1 - 0.013 15.8 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain Kdo PF06293.9 ETS62728.1 - 0.015 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.6 ETS62728.1 - 0.031 14.3 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 ETS62728.1 - 0.11 11.3 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Herpes_UL6 PF01763.11 ETS62728.1 - 1.5 6.9 0.0 3 5.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like FAM91_C PF14648.1 ETS62728.1 - 2.1 7.0 0.0 3.9 6.1 0.0 1.3 1 0 0 1 1 1 0 FAM91 C-terminus Gly_transf_sug PF04488.10 ETS62729.1 - 1.7e-20 73.3 0.0 3.3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 ETS62729.1 - 0.031 12.7 1.8 0.09 11.2 0.2 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Mito_carr PF00153.22 ETS62730.1 - 1.5e-81 268.2 0.1 2.5e-27 94.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.16 ETS62731.1 - 2.4e-94 316.6 0.0 3.2e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 Amidase ERG4_ERG24 PF01222.12 ETS62732.1 - 6e-125 417.1 20.7 7e-125 416.9 14.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ribosomal_L29e PF01779.12 ETS62734.1 - 3.2e-21 74.9 6.5 5.2e-21 74.2 4.5 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF1237 PF06824.6 ETS62735.1 - 1.7e-155 517.7 0.0 2.1e-155 517.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PHD PF00628.24 ETS62736.1 - 7.2e-12 44.8 16.5 2.1e-07 30.4 2.0 3.8 4 0 0 4 4 4 2 PHD-finger zf-PHD-like PF15446.1 ETS62736.1 - 2.9 7.1 4.1 5 6.3 0.9 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 ETS62736.1 - 3 8.0 5.2 0.62 10.2 0.6 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain Vps51 PF08700.6 ETS62737.1 - 2.9e-13 49.4 0.0 1.3e-12 47.4 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Pro_isomerase PF00160.16 ETS62738.1 - 2.9e-50 170.4 0.0 3.2e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Histone PF00125.19 ETS62739.1 - 7.3e-26 90.0 0.0 9.2e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETS62739.1 - 1.1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS62740.1 - 1.4e-22 79.5 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETS62740.1 - 3e-06 27.2 1.9 3e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 ETS62740.1 - 0.00032 20.9 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 ETS62740.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 ETS62740.1 - 0.021 15.3 0.3 0.027 14.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 ETS62740.1 - 0.07 12.5 0.1 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Snf7 PF03357.16 ETS62741.1 - 5.4e-30 104.0 19.4 5.4e-30 104.0 13.5 1.4 1 1 0 1 1 1 1 Snf7 ACT_5 PF13710.1 ETS62741.1 - 0.041 13.6 1.5 0.11 12.3 0.2 2.2 2 0 0 2 2 2 0 ACT domain Eno-Rase_FAD_bd PF07055.7 ETS62741.1 - 0.099 12.5 0.9 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain MIP PF00230.15 ETS62744.1 - 1.9e-47 161.6 8.2 2.3e-47 161.3 5.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein PPI_Ypi1 PF07491.6 ETS62745.1 - 2.8e-24 84.5 3.2 2.8e-24 84.5 2.2 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor TATR PF03430.8 ETS62745.1 - 0.059 12.0 3.9 0.056 12.0 2.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator CDC45 PF02724.9 ETS62745.1 - 1.6 6.6 10.8 2 6.3 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 ETS62745.1 - 3.6 6.5 8.8 3.6 6.5 6.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 ETS62746.1 - 5.7e-26 91.2 0.0 1.7e-25 89.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62746.1 - 3.7e-13 49.1 0.0 1.3e-12 47.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.1 ETS62746.1 - 0.00017 21.3 4.7 0.00017 21.3 3.3 2.1 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 ETS62746.1 - 0.00023 20.5 0.4 0.00042 19.7 0.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger zf-Apc11 PF12861.2 ETS62746.1 - 0.035 13.9 1.4 0.077 12.8 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Kinase-like PF14531.1 ETS62746.1 - 0.035 13.0 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FANCL_C PF11793.3 ETS62746.1 - 0.067 13.1 6.9 0.014 15.3 2.2 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-rbx1 PF12678.2 ETS62746.1 - 0.21 11.7 3.0 0.12 12.4 0.5 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_5 PF14634.1 ETS62746.1 - 0.49 10.1 8.1 0.055 13.2 2.1 2.2 3 0 0 3 3 3 0 zinc-RING finger domain RINGv PF12906.2 ETS62746.1 - 0.65 10.0 5.3 1.5 8.9 3.7 1.7 1 0 0 1 1 1 0 RING-variant domain TPR_MLP1_2 PF07926.7 ETS62747.1 - 0.15 11.8 5.2 0.59 9.8 3.1 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 ETS62747.1 - 0.17 10.5 5.4 0.066 11.8 1.7 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 ETS62747.1 - 0.3 10.8 4.5 0.8 9.4 1.0 2.9 3 0 0 3 3 3 0 Laminin Domain II DUF4407 PF14362.1 ETS62747.1 - 2.2 7.1 11.1 3.9 6.3 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.17 ETS62747.1 - 7.1 6.7 9.7 2.5 8.1 3.7 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UDP-g_GGTase PF06427.6 ETS62749.1 - 4.6e-55 186.1 0.0 9.8e-55 185.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 ETS62749.1 - 2e-08 33.8 0.0 3.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DPBB_1 PF03330.13 ETS62751.1 - 4e-10 39.5 1.4 5.1e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 ETS62752.1 - 5.5e-62 209.2 0.0 8.2e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62752.1 - 5.6e-36 123.9 0.0 4.4e-34 117.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS62752.1 - 5.6e-05 22.2 0.0 0.0015 17.5 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.6 ETS62752.1 - 0.012 14.4 0.1 0.038 12.8 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.17 ETS62752.1 - 0.014 14.7 0.2 0.14 11.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 ETS62752.1 - 0.04 13.6 0.0 0.19 11.4 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family GST_N_2 PF13409.1 ETS62753.1 - 3.3e-20 71.8 0.0 5.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS62753.1 - 5.9e-13 48.5 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS62753.1 - 0.0018 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS62753.1 - 0.035 14.3 0.1 0.24 11.6 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RasGEF PF00617.14 ETS62754.1 - 2.5e-53 180.6 0.0 4.3e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETS62754.1 - 9.6e-26 89.9 0.0 1.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.12 ETS62754.1 - 2.8e-14 52.3 0.1 6.1e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 ETS62754.1 - 4.1e-14 51.8 0.1 8.2e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS62754.1 - 1e-12 47.2 0.0 1.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain 2-oxoacid_dh PF00198.18 ETS62755.1 - 1.9e-77 259.6 0.1 2.8e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 ETS62755.1 - 7.6e-20 70.3 2.3 1.3e-19 69.5 1.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 ETS62755.1 - 1.9e-05 24.2 1.7 0.0029 17.2 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like RebB PF11747.3 ETS62755.1 - 0.00028 20.6 1.2 0.00028 20.6 0.8 2.0 2 0 0 2 2 1 1 Killing trait HlyD_3 PF13437.1 ETS62755.1 - 0.00032 20.9 0.2 0.98 9.7 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 ETS62755.1 - 0.0014 18.3 0.9 0.0029 17.2 0.6 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_2 PF12700.2 ETS62755.1 - 0.0015 17.7 9.3 0.0063 15.7 4.5 2.2 1 1 1 2 2 2 1 HlyD family secretion protein MIP-T3 PF10243.4 ETS62755.1 - 0.18 10.2 24.9 0.31 9.4 17.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SGT1 PF07093.6 ETS62755.1 - 0.22 9.8 12.4 0.29 9.4 8.6 1.1 1 0 0 1 1 1 0 SGT1 protein AF-4 PF05110.8 ETS62755.1 - 2.2 6.0 36.6 0.68 7.7 17.4 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Macoilin PF09726.4 ETS62755.1 - 5.5 5.1 15.0 7.3 4.7 10.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Amidohydro_2 PF04909.9 ETS62758.1 - 3.1e-09 36.8 0.1 4.6e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 ETS62758.1 - 5.1e-07 29.9 0.7 9.1e-07 29.1 0.5 1.4 1 0 0 1 1 1 1 Amidohydrolase FUN14 PF04930.10 ETS62759.1 - 2.1e-22 79.2 0.2 4e-22 78.3 0.2 1.5 1 0 0 1 1 1 1 FUN14 family LSM PF01423.17 ETS62761.1 - 4.3e-16 58.2 0.0 5.4e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain PRELI PF04707.9 ETS62762.1 - 3.2e-14 52.7 2.2 0.00052 19.6 0.0 4.2 4 0 0 4 4 4 4 PRELI-like family Bromodomain PF00439.20 ETS62764.1 - 1.1e-14 54.1 0.0 2.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain LKAAEAR PF15478.1 ETS62764.1 - 0.032 14.4 2.5 0.07 13.3 1.0 2.1 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif MFS_1 PF07690.11 ETS62765.1 - 7.8e-24 84.0 12.9 2.7e-23 82.2 8.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIID_30kDa PF03540.8 ETS62766.1 - 4e-26 90.5 0.0 7.4e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 ETS62766.1 - 2.9e-05 23.7 0.0 0.0057 16.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain Ribosomal_60s PF00428.14 ETS62766.1 - 0.081 13.3 0.1 0.081 13.3 0.0 4.4 4 1 0 4 4 4 0 60s Acidic ribosomal protein FoP_duplication PF13865.1 ETS62766.1 - 0.11 12.9 0.8 0.37 11.2 0.5 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 tRNA-synt_2d PF01409.15 ETS62768.1 - 8e-87 290.5 0.0 1.1e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 ETS62768.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 ETS62768.1 - 5e-05 22.2 0.1 0.00098 17.9 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) IBN_N PF03810.14 ETS62769.1 - 2.4e-09 36.9 1.6 3.4e-07 30.0 0.4 3.6 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 ETS62769.1 - 0.023 14.6 0.0 0.12 12.3 0.0 2.3 1 0 0 1 1 1 0 Exportin 1-like protein G-patch PF01585.18 ETS62770.1 - 5.4e-12 45.2 1.4 3.2e-08 33.2 0.6 2.6 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.2 ETS62770.1 - 0.0001 22.0 0.3 0.038 13.8 0.1 2.8 2 0 0 2 2 2 2 DExH-box splicing factor binding site Acetyltransf_1 PF00583.19 ETS62771.1 - 1.4e-11 44.2 0.0 2.4e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS62771.1 - 2.9e-05 24.1 0.0 4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS62771.1 - 0.00079 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS62771.1 - 0.0009 18.9 0.0 0.0091 15.7 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Alpha_E3_glycop PF01563.11 ETS62771.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein KaiC PF06745.8 ETS62771.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 KaiC Med20 PF08612.6 ETS62772.1 - 0.013 14.6 0.0 2.9 6.9 0.0 2.8 2 1 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Macoilin PF09726.4 ETS62772.1 - 0.22 9.7 3.5 0.37 9.0 2.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Nop25 PF09805.4 ETS62772.1 - 7.7 6.5 12.8 2.6 8.0 3.1 2.4 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF410 PF04190.8 ETS62773.1 - 3.5e-24 85.7 0.0 2.7e-23 82.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF410) PROCN PF08083.6 ETS62774.1 - 4.8e-192 637.9 2.3 7.1e-192 637.3 1.6 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 ETS62774.1 - 2.5e-122 406.5 0.6 4.3e-122 405.7 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 ETS62774.1 - 1e-85 284.9 0.5 3.2e-85 283.3 0.4 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 ETS62774.1 - 1.9e-77 258.1 3.4 4.8e-77 256.8 2.3 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 ETS62774.1 - 4.2e-60 201.2 0.0 8.8e-60 200.2 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 ETS62774.1 - 3e-44 148.7 0.3 7.2e-44 147.5 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 ETS62774.1 - 6.9e-33 113.0 0.0 1.4e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 ETS62774.1 - 0.0023 17.6 0.0 0.0071 16.0 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APC_CDC26 PF10471.4 ETS62776.1 - 3.8e-05 24.3 3.1 0.0002 21.9 2.2 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 M_domain PF12938.2 ETS62776.1 - 0.39 10.5 6.3 0.5 10.1 4.4 1.1 1 0 0 1 1 1 0 M domain of GW182 SelP_N PF04592.9 ETS62776.1 - 2.6 7.3 5.8 2.9 7.1 4.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pyr_redox_3 PF13738.1 ETS62777.1 - 6e-16 59.1 0.1 4.3e-15 56.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS62777.1 - 2.7e-13 48.9 0.0 3.2e-07 28.9 0.0 3.8 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 ETS62777.1 - 4.3e-08 33.0 0.1 1.8e-06 27.8 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 ETS62777.1 - 3.2e-07 29.6 0.1 3e-05 23.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS62777.1 - 4.4e-06 26.7 0.0 0.00028 20.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS62777.1 - 0.0024 17.8 0.1 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS62777.1 - 0.013 14.4 0.5 0.044 12.6 0.2 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 ETS62777.1 - 0.1 12.8 0.0 23 5.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding JAB PF01398.16 ETS62778.1 - 9.5e-34 115.5 0.0 1.7e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETS62778.1 - 6.3e-28 97.1 1.4 6.3e-28 97.1 1.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 ETS62778.1 - 5.7e-07 29.0 0.0 9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Exotox-A_target PF09102.5 ETS62778.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A, targeting Arf PF00025.16 ETS62779.1 - 7.2e-36 123.0 0.0 3.5e-25 88.2 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 ETS62779.1 - 2.2e-13 49.9 0.0 2e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 ETS62779.1 - 3.4e-08 32.9 0.0 7.2e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 ETS62779.1 - 5.7e-08 33.2 0.0 1.5e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 ETS62779.1 - 5.6e-07 28.9 0.0 7.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 ETS62779.1 - 9e-06 24.6 0.1 1.6e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 ETS62779.1 - 2.8e-05 24.0 0.0 4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETS62779.1 - 0.00064 19.5 0.0 0.12 12.1 0.1 2.2 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 ETS62779.1 - 0.015 14.6 0.0 6.7 6.0 0.0 2.9 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Vps52 PF04129.7 ETS62780.1 - 9.7e-34 116.7 0.0 1.7e-22 79.6 0.0 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family FTA4 PF13093.1 ETS62780.1 - 0.036 13.4 3.6 1.2 8.5 0.5 2.3 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sec3_C PF09763.4 ETS62780.1 - 0.11 10.6 0.0 0.51 8.4 0.0 1.9 1 1 0 1 1 1 0 Exocyst complex component Sec3 Herpes_capsid PF06112.6 ETS62780.1 - 3.1 7.8 11.1 0.17 11.9 3.3 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein RIC1 PF07064.8 ETS62781.1 - 4.3e-70 236.0 0.0 1.5e-38 132.7 0.0 2.2 2 0 0 2 2 2 2 RIC1 DUF914 PF06027.7 ETS62781.1 - 0.43 9.3 0.0 0.71 8.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) PQ-loop PF04193.9 ETS62782.1 - 9.2e-37 124.4 5.4 1.4e-19 69.3 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Sre PF03125.13 ETS62782.1 - 0.15 10.9 0.7 0.22 10.4 0.5 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor ECH PF00378.15 ETS62784.1 - 2.3e-17 62.9 0.2 4.1e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 ETS62784.1 - 2.2e-10 40.3 0.1 4.1e-09 36.2 0.0 2.7 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 ETS62784.1 - 5.1e-06 26.4 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.11 ETS62786.1 - 6.7e-36 123.7 24.8 6.7e-36 123.7 17.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily CIAPIN1 PF05093.8 ETS62787.1 - 7.3e-32 109.4 4.0 1.5e-31 108.4 2.8 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis WBS_methylT PF12589.3 ETS62788.1 - 5.9e-18 65.1 9.3 1.1e-17 64.2 6.5 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 ETS62788.1 - 4e-11 43.2 0.0 8.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS62788.1 - 2.5e-08 33.8 0.0 4.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS62788.1 - 2.9e-06 27.6 0.0 7.9e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS62788.1 - 4.6e-06 26.9 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS62788.1 - 5.8e-06 25.9 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS62788.1 - 1.1e-05 25.9 0.0 1.9e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS62788.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 ETS62788.1 - 0.0028 17.7 0.0 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.13 ETS62788.1 - 0.039 13.4 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 DNA methylase adh_short PF00106.20 ETS62790.1 - 0.0033 17.3 7.4 0.66 9.8 0.1 2.7 1 1 1 2 2 2 2 short chain dehydrogenase Peptidase_S9 PF00326.16 ETS62792.1 - 1.7e-41 141.8 0.1 4.9e-29 101.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family PIG-H PF10181.4 ETS62792.1 - 6e-13 48.2 0.0 1.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Abhydrolase_5 PF12695.2 ETS62792.1 - 3.5e-10 39.8 6.2 5.2e-07 29.5 0.2 3.0 3 1 0 3 3 3 2 Alpha/beta hydrolase family DLH PF01738.13 ETS62792.1 - 4.6e-08 32.6 0.0 8.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 ETS62792.1 - 1.5e-05 24.7 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 ETS62792.1 - 8.7e-05 22.5 7.2 0.0011 18.9 2.5 3.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 ETS62792.1 - 0.0035 17.2 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS62792.1 - 0.012 15.2 0.6 0.35 10.3 0.0 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 ETS62792.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) eRF1_1 PF03463.10 ETS62793.1 - 5.5e-56 187.7 0.0 7.8e-56 187.2 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 ETS62793.1 - 2.5e-23 82.4 0.0 5e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 ETS62793.1 - 3.4e-22 79.2 0.0 5.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 YadA_anchor PF03895.10 ETS62793.1 - 0.17 11.9 4.0 0.33 10.9 2.8 1.4 1 0 0 1 1 1 0 YadA-like C-terminal region L51_S25_CI-B8 PF05047.11 ETS62794.1 - 2.9e-14 52.5 0.0 3.6e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RAI16-like PF10257.4 ETS62795.1 - 8.7e-66 222.2 0.0 1.4e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Pex24p PF06398.6 ETS62796.1 - 1.8e-22 79.6 18.3 2.3e-22 79.2 6.3 3.1 2 2 0 2 2 2 2 Integral peroxisomal membrane peroxin PIG-S PF10510.4 ETS62797.1 - 3.3e-110 369.1 4.7 1.7e-109 366.8 3.3 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Aldo_ket_red PF00248.16 ETS62798.1 - 4.5e-51 173.3 0.0 6.8e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.18 ETS62799.1 - 0.00019 21.1 0.4 0.00047 19.9 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Zn_clus PF00172.13 ETS62800.1 - 0.0016 18.3 7.5 0.0016 18.3 5.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec39 PF08314.6 ETS62801.1 - 4.1e-41 140.7 0.0 1.7e-40 138.6 0.0 1.9 2 0 0 2 2 2 1 Secretory pathway protein Sec39 Med21 PF11221.3 ETS62802.1 - 1.6e-12 47.6 4.6 2.2e-12 47.1 3.2 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spc7 PF08317.6 ETS62802.1 - 0.0073 15.0 1.5 0.0096 14.6 1.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Syntaxin_2 PF14523.1 ETS62802.1 - 0.013 15.5 0.5 0.019 14.9 0.3 1.4 1 0 0 1 1 1 0 Syntaxin-like protein DUF3135 PF11333.3 ETS62802.1 - 0.044 13.9 2.7 0.17 12.0 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) DUF948 PF06103.6 ETS62802.1 - 0.089 12.6 1.5 1.1 9.1 1.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HisKA_3 PF07730.8 ETS62802.1 - 0.19 12.1 2.7 8.6 6.7 1.0 2.3 1 1 1 2 2 2 0 Histidine kinase CENP-Q PF13094.1 ETS62802.1 - 0.54 10.2 4.7 1.8 8.5 2.2 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med11 PF10280.4 ETS62802.1 - 0.77 9.8 4.1 0.58 10.2 1.4 1.8 1 1 1 2 2 2 0 Mediator complex protein Baculo_PEP_C PF04513.7 ETS62802.1 - 1.6 8.5 4.7 1.2 8.9 1.1 2.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ICMT PF04140.9 ETS62803.1 - 5.7e-25 87.3 1.1 7.9e-25 86.8 0.1 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETS62803.1 - 2.2e-13 50.2 0.6 2.2e-13 50.2 0.4 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 ETS62803.1 - 0.00062 19.1 1.0 0.001 18.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3172 PF11371.3 ETS62803.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Ribosomal_S18 PF01084.15 ETS62804.1 - 3.8e-19 68.2 0.0 9e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Acetyltransf_2 PF00797.12 ETS62805.1 - 3e-23 82.6 0.3 9e-22 77.8 0.0 2.4 2 1 0 2 2 2 1 N-acetyltransferase PQQ_3 PF13570.1 ETS62806.1 - 5.8e-06 26.4 2.5 0.086 13.1 0.0 5.1 6 0 0 6 6 6 1 PQQ-like domain WD40 PF00400.27 ETS62806.1 - 1.1e-05 25.1 30.3 0.064 13.1 0.1 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 ETS62806.1 - 0.0028 17.1 0.2 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain Nucleoplasmin PF03066.10 ETS62806.1 - 0.015 14.8 2.2 0.021 14.3 1.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 ETS62806.1 - 1.4 9.2 7.5 2.4 8.5 5.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 ETS62806.1 - 1.8 6.4 5.2 2.6 5.9 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 ETS62806.1 - 3.1 7.3 7.0 4.3 6.9 4.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 ETS62806.1 - 5.6 5.5 12.5 9 4.9 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 ETS62806.1 - 5.7 6.1 6.5 7.7 5.6 4.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 ETS62806.1 - 6.9 6.8 8.7 14 5.9 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cactin_mid PF10312.4 ETS62807.1 - 1.3e-64 216.9 6.4 3.6e-64 215.5 4.4 1.8 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 ETS62807.1 - 8.7e-60 199.8 4.9 1.7e-59 198.9 3.4 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein eIF-5a PF01287.15 ETS62807.1 - 0.23 11.4 2.4 3.8 7.5 0.7 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold AD PF09793.4 ETS62808.1 - 5.8e-22 77.3 0.0 1.4e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain DUF1885 PF08968.5 ETS62808.1 - 0.082 12.5 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1885) Patched PF02460.13 ETS62809.1 - 3.3e-61 207.2 3.1 4.7e-33 114.1 0.2 3.0 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 ETS62809.1 - 5.2e-42 142.8 12.2 5.6e-21 74.5 0.3 3.5 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.9 ETS62809.1 - 0.0038 16.8 2.5 0.0079 15.8 1.7 1.4 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.14 ETS62809.1 - 0.03 11.7 0.9 0.046 11.1 0.6 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Stn1 PF10451.4 ETS62811.1 - 0.032 13.0 0.0 0.066 12.0 0.0 1.5 1 0 0 1 1 1 0 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 ETS62811.1 - 0.068 13.0 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain CHZ PF09649.5 ETS62812.1 - 2.6e-11 42.5 0.2 2.6e-11 42.5 0.1 3.0 4 0 0 4 4 4 1 Histone chaperone domain CHZ RNA_pol_3_Rpc31 PF11705.3 ETS62812.1 - 0.0081 16.1 10.5 0.0081 16.1 7.3 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.5 ETS62812.1 - 0.058 13.4 2.9 0.098 12.6 2.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nucleo_P87 PF07267.6 ETS62812.1 - 0.52 8.9 4.3 0.62 8.6 3.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ebola_NP PF05505.7 ETS62812.1 - 1.5 6.8 10.8 1.5 6.8 7.5 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein NOA36 PF06524.7 ETS62812.1 - 1.6 7.9 14.9 2.7 7.1 10.3 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 ETS62812.1 - 2.9 7.5 15.6 0.14 11.8 7.4 1.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 ETS62812.1 - 4.3 5.2 10.0 4.9 5.0 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETS62812.1 - 8.6 4.1 20.6 9.7 3.9 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpb4 PF03874.11 ETS62813.1 - 1.9e-25 89.1 0.5 2.4e-25 88.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.27 ETS62814.1 - 4.8e-39 130.8 9.1 2.1e-09 36.9 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 ETS62814.1 - 1.1e-23 83.0 6.0 2.2e-23 82.0 4.2 1.5 1 0 0 1 1 1 1 Sof1-like domain Nucleoporin_N PF08801.6 ETS62814.1 - 0.0022 16.7 0.4 3.5 6.2 0.0 4.4 3 1 1 5 5 5 1 Nup133 N terminal like CBFB_NFYA PF02045.10 ETS62815.1 - 2e-27 95.4 11.4 2e-27 95.4 7.9 2.5 2 1 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ThuA PF06283.6 ETS62816.1 - 8.1e-42 143.3 0.0 1.3e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose utilisation DUF3446 PF11928.3 ETS62816.1 - 0.027 14.6 6.1 0.097 12.8 4.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) BPL_N PF09825.4 ETS62816.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Sporozoite_P67 PF05642.6 ETS62816.1 - 0.58 7.9 6.7 0.76 7.5 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kelch_4 PF13418.1 ETS62817.1 - 4.1e-33 112.9 1.5 1.1e-06 28.2 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 ETS62817.1 - 3.6e-31 106.5 5.1 3.2e-07 30.3 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain DUF4110 PF13422.1 ETS62817.1 - 1.8e-22 78.9 0.1 1.8e-22 78.9 0.1 3.5 3 2 1 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 ETS62817.1 - 4.6e-19 67.7 6.3 0.00032 20.7 0.0 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.1 ETS62817.1 - 8.2e-19 67.1 3.3 2.2e-05 24.2 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 ETS62817.1 - 4.6e-14 51.6 2.3 0.00015 21.2 0.0 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 ETS62817.1 - 9.7e-13 47.3 0.7 0.015 15.0 0.0 5.2 6 0 0 6 6 6 3 Kelch motif Pox_Ag35 PF03286.9 ETS62817.1 - 0.0039 16.7 7.9 0.0039 16.7 5.5 3.0 3 0 0 3 3 3 1 Pox virus Ag35 surface protein Adaptin_binding PF10199.4 ETS62817.1 - 0.015 15.5 19.7 0.059 13.6 0.3 3.5 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 BUD22 PF09073.5 ETS62817.1 - 0.53 9.2 39.2 0.007 15.4 14.4 2.3 2 0 0 2 2 2 0 BUD22 ECH PF00378.15 ETS62818.1 - 1.1e-19 70.5 0.0 1.2e-17 63.8 0.0 2.5 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family DUF1731 PF08338.6 ETS62818.1 - 0.026 14.0 0.3 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Myb_DNA-bind_2 PF08914.6 ETS62820.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Rap1 Myb domain Actin PF00022.14 ETS62821.1 - 9.9e-134 445.6 0.0 1.1e-133 445.4 0.0 1.0 1 0 0 1 1 1 1 Actin DUF1077 PF06417.7 ETS62822.1 - 1.3e-45 153.7 0.4 2.5e-45 152.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) adh_short PF00106.20 ETS62822.1 - 1.9e-27 96.2 6.3 1.9e-27 96.2 4.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS62822.1 - 4.9e-23 82.1 0.0 7.9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS62822.1 - 9.4e-13 48.2 4.0 9.4e-13 48.2 2.7 1.9 2 0 0 2 2 2 1 KR domain AhpC-TSA_2 PF13911.1 ETS62822.1 - 2.3e-11 43.5 0.0 1.6e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 ETS62822.1 - 0.0016 18.0 0.0 0.0055 16.2 0.0 1.8 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 ETS62822.1 - 0.036 13.7 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Eno-Rase_NADH_b PF12242.3 ETS62822.1 - 0.041 13.6 6.0 0.039 13.7 1.9 2.4 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DHQ_synthase PF01761.15 ETS62823.1 - 7.9e-50 169.2 0.0 1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 ETS62823.1 - 4.9e-12 45.6 0.0 7.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cellulase-like PF12876.2 ETS62824.1 - 0.00011 22.5 0.1 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Rad17 PF03215.10 ETS62825.1 - 1.4e-43 149.3 0.0 4e-43 147.8 0.0 1.7 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 ETS62825.1 - 0.005 16.8 1.6 0.0095 15.9 0.3 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS62825.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IBN_N PF03810.14 ETS62826.1 - 1.5e-15 56.8 0.0 5.7e-15 54.9 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 ETS62826.1 - 1e-07 30.8 0.0 2.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 ETS62826.1 - 0.048 13.5 0.0 0.28 11.1 0.0 2.4 1 0 0 1 1 1 0 Exportin 1-like protein HEAT PF02985.17 ETS62826.1 - 0.088 12.9 1.1 9 6.6 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Inhibitor_I9 PF05922.11 ETS62826.1 - 0.088 13.3 0.0 2.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Peptidase inhibitor I9 TFIIA PF03153.8 ETS62826.1 - 0.089 12.6 7.7 0.29 11.0 5.3 1.9 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Translin PF01997.11 ETS62827.1 - 1.3e-38 132.6 0.1 1.6e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Translin family DivIC PF04977.10 ETS62827.1 - 0.35 10.3 2.0 7.8 6.0 0.2 2.9 3 0 0 3 3 3 0 Septum formation initiator Ribosomal_L1 PF00687.16 ETS62828.1 - 5.3e-52 176.3 0.0 7.5e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RR_TM4-6 PF06459.7 ETS62828.1 - 0.31 10.9 2.2 0.42 10.4 1.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4336 PF14234.1 ETS62829.1 - 3.5e-08 32.9 0.1 0.076 12.1 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) Rap1-DNA-bind PF09197.5 ETS62829.1 - 0.029 14.8 0.1 0.052 14.0 0.1 1.4 1 0 0 1 1 1 0 Rap1, DNA-binding ATPgrasp_Ter PF15632.1 ETS62830.1 - 4.5e-05 22.3 0.0 0.0016 17.2 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DUF3608 PF12257.3 ETS62831.1 - 1.2e-74 250.8 0.0 1.9e-74 250.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 ETS62831.1 - 1.9e-19 69.1 0.2 4.3e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2 PF01569.16 ETS62832.1 - 5.6e-12 45.4 11.3 5.6e-12 45.4 7.8 2.1 2 2 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 ETS62832.1 - 1e-06 28.4 12.6 3.7e-06 26.5 8.7 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF4070 PF13282.1 ETS62832.1 - 0.1 12.1 0.9 0.19 11.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) DUF4449 PF14613.1 ETS62833.1 - 8.6e-08 32.2 0.1 8.6e-08 32.2 0.0 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) Katanin_con80 PF13925.1 ETS62833.1 - 0.022 14.5 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 con80 domain of Katanin DUF913 PF06025.7 ETS62833.1 - 0.12 11.0 1.2 0.3 9.7 0.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF883 PF05957.8 ETS62833.1 - 0.32 11.4 42.2 0.75 10.2 3.1 6.9 4 1 2 7 7 7 0 Bacterial protein of unknown function (DUF883) Nif11 PF07862.6 ETS62833.1 - 0.94 9.4 9.2 4.8 7.2 0.0 4.6 5 0 0 5 5 5 0 Nitrogen fixation protein of unknown function HisKA_3 PF07730.8 ETS62833.1 - 4.4 7.7 21.5 5.7 7.3 0.6 7.1 7 1 0 7 7 7 0 Histidine kinase Acetyltransf_1 PF00583.19 ETS62834.1 - 3e-14 52.7 0.4 4.8e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETS62834.1 - 1.9e-09 37.1 0.1 3e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETS62834.1 - 2.1e-08 34.2 0.0 2.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS62834.1 - 1.7e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS62834.1 - 2.1e-06 27.7 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS62834.1 - 3.8e-06 27.1 0.0 4.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS62834.1 - 5.3e-05 23.0 0.1 8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS62834.1 - 0.00089 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Aminotran_1_2 PF00155.16 ETS62836.1 - 1.9e-33 115.9 0.0 4.7e-33 114.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS62836.1 - 3.1e-05 23.2 0.0 5.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 ETS62836.1 - 0.28 9.5 0.0 0.41 9.0 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) TPR_11 PF13414.1 ETS62837.1 - 8.9e-23 79.7 14.9 9e-14 50.8 0.9 2.8 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETS62837.1 - 3.6e-12 45.3 7.0 1.5e-05 24.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.1 ETS62837.1 - 5.6e-12 45.4 0.0 9.4e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_16 PF13432.1 ETS62837.1 - 5.5e-07 30.0 12.9 0.0023 18.5 0.1 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS62837.1 - 6.5e-07 28.7 17.3 0.0029 17.4 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS62837.1 - 0.00085 19.6 9.5 0.74 10.1 0.3 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS62837.1 - 0.0022 18.0 2.9 0.0061 16.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS62837.1 - 0.0048 16.7 1.2 0.014 15.1 0.9 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS62837.1 - 0.031 14.1 0.4 0.83 9.5 0.0 2.4 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 ETS62837.1 - 0.19 12.4 11.9 0.26 12.0 1.7 4.4 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETS62837.1 - 2.9 8.0 7.2 1.3 9.2 1.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3987 PF13148.1 ETS62838.1 - 0.072 11.6 3.7 0.071 11.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FAM176 PF14851.1 ETS62838.1 - 2.8 7.5 8.9 1.9 8.1 0.1 2.1 2 0 0 2 2 2 0 FAM176 family ATP-synt_ab PF00006.20 ETS62839.1 - 7.2e-60 202.1 0.0 1.2e-59 201.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DAO PF01266.19 ETS62839.1 - 3.1e-48 164.4 0.4 5.3e-48 163.7 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ATP-synt_ab_C PF00306.22 ETS62839.1 - 4.7e-17 62.4 0.1 3.2e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETS62839.1 - 1e-11 44.8 0.3 2.7e-11 43.5 0.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain EF-hand_7 PF13499.1 ETS62839.1 - 2.6e-08 33.8 1.7 1.3e-07 31.6 1.2 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETS62839.1 - 1.4e-07 30.7 2.3 1.4e-05 24.5 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 ETS62839.1 - 3.8e-06 25.8 0.7 0.0011 18.0 0.1 2.7 2 0 0 2 2 2 1 EF hand FAD_oxidored PF12831.2 ETS62839.1 - 4e-06 26.1 1.8 4.9e-06 25.8 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase EF-hand_8 PF13833.1 ETS62839.1 - 0.0001 21.8 2.0 0.0012 18.3 0.6 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 ETS62839.1 - 0.0002 20.5 0.5 0.00052 19.2 0.3 1.8 1 0 0 1 1 1 1 EF hand FAD_binding_3 PF01494.14 ETS62839.1 - 0.00038 19.6 1.5 0.006 15.6 1.0 2.2 1 1 0 1 1 1 1 FAD binding domain HAS-barrel PF09378.5 ETS62839.1 - 0.0012 18.6 0.2 0.0029 17.4 0.2 1.6 1 0 0 1 1 1 1 HAS barrel domain GIDA PF01134.17 ETS62839.1 - 0.0015 17.5 0.3 0.047 12.5 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETS62839.1 - 0.002 18.0 0.3 0.0098 15.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS62839.1 - 0.012 15.2 0.3 0.036 13.7 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 ETS62839.1 - 0.023 13.5 6.4 0.012 14.5 2.7 1.8 2 1 0 2 2 2 0 FAD binding domain EF-hand_9 PF14658.1 ETS62839.1 - 0.03 14.2 0.1 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Pyr_redox_3 PF13738.1 ETS62839.1 - 0.052 13.5 0.1 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SPARC_Ca_bdg PF10591.4 ETS62839.1 - 0.12 12.4 0.1 0.36 10.8 0.1 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Pyr_redox PF00070.22 ETS62839.1 - 0.14 12.6 1.1 0.45 10.9 0.8 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS62839.1 - 0.14 10.5 1.1 0.26 9.7 0.7 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF3533 PF12051.3 ETS62839.1 - 0.21 10.2 0.0 0.36 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) NAD_binding_8 PF13450.1 ETS62839.1 - 0.89 9.6 4.2 0.4 10.7 0.3 2.5 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Brix PF04427.13 ETS62841.1 - 6.3e-46 156.4 0.1 8.1e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 Brix domain Ribosomal_L28 PF00830.14 ETS62842.1 - 1.5e-22 79.1 0.2 2.9e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L28 family PIN_4 PF13638.1 ETS62843.1 - 0.0002 21.4 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 PIN domain Sec23_trunk PF04811.10 ETS62844.1 - 7.1e-77 258.0 0.0 9.9e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETS62844.1 - 1.8e-35 120.4 0.2 3.3e-35 119.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 ETS62844.1 - 1.3e-30 105.7 0.0 2.3e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 ETS62844.1 - 6.5e-17 60.8 6.2 1.3e-16 59.8 4.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 ETS62844.1 - 1.1e-11 44.3 0.0 2.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DnaJ PF00226.26 ETS62845.1 - 8.2e-07 28.6 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 ETS62845.1 - 9.1e-05 22.2 0.0 0.00016 21.4 0.0 1.5 2 0 0 2 2 2 1 Pam16 WD40 PF00400.27 ETS62846.1 - 4.6e-11 42.1 1.8 0.0035 17.1 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETS62846.1 - 0.12 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region SNARE PF05739.14 ETS62847.1 - 2.3e-09 36.8 0.1 3.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 ETS62847.1 - 0.0002 20.8 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4316 PF14195.1 ETS62847.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DUF1664 PF07889.7 ETS62847.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DPBB_1 PF03330.13 ETS62848.1 - 2.4e-05 24.2 0.2 4.4e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 ETS62848.1 - 0.00069 19.2 1.1 0.001 18.7 0.5 1.4 1 1 0 1 1 1 1 Barwin family TIM21 PF08294.6 ETS62849.1 - 5.1e-14 52.1 0.0 1.5e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 TIM21 OapA PF04225.7 ETS62849.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain Yippee-Mis18 PF03226.9 ETS62850.1 - 6.6e-22 77.3 0.2 7.6e-22 77.1 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Toxin_6 PF05453.7 ETS62850.1 - 0.061 13.5 0.5 2 8.7 0.1 2.3 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family Evr1_Alr PF04777.8 ETS62850.1 - 0.15 11.9 1.5 0.41 10.5 0.2 2.0 1 1 1 2 2 2 0 Erv1 / Alr family Endonuclease_7 PF02945.10 ETS62850.1 - 0.25 11.0 2.2 1.2 8.8 1.5 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII BSP_II PF05432.6 ETS62851.1 - 0.031 13.5 2.8 0.047 12.9 2.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 ETS62851.1 - 0.038 13.4 1.3 0.055 12.9 0.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 ETS62851.1 - 0.054 13.8 5.4 0.091 13.0 3.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Destabilase PF05497.7 ETS62851.1 - 0.069 13.2 1.5 0.14 12.2 0.4 1.9 1 1 0 2 2 2 0 Destabilase TRAP_alpha PF03896.11 ETS62851.1 - 0.077 11.9 1.5 0.12 11.3 1.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Arylesterase PF01731.15 ETS62852.1 - 0.17 11.8 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Arylesterase Ribosomal_L19e PF01280.15 ETS62853.1 - 1.9e-61 206.1 10.3 1.9e-61 206.1 7.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e Ribosomal_S27e PF01667.12 ETS62854.1 - 9e-27 92.3 4.5 9e-27 92.3 3.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S27 HapK PF11639.3 ETS62854.1 - 0.043 14.4 0.0 0.077 13.6 0.0 1.4 1 0 0 1 1 1 0 REDY-like protein HapK PhrC_PhrF PF11131.3 ETS62854.1 - 1.8 8.1 4.4 8.3 6.0 0.0 2.9 3 0 0 3 3 3 0 Rap-phr extracellular signalling zf-DHHC PF01529.15 ETS62855.1 - 3.8e-38 130.5 7.5 7e-38 129.7 5.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase QueC PF06508.8 ETS62855.1 - 2.9 7.1 5.3 4.7 6.4 3.6 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Longin PF13774.1 ETS62856.1 - 5.6e-16 57.8 0.0 1.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 ETS62856.1 - 2.7e-14 52.5 0.7 5e-14 51.6 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Herpes_teg_N PF04843.7 ETS62856.1 - 0.09 12.1 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region CENP-L PF13092.1 ETS62857.1 - 2.4e-09 37.1 0.0 5.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Glucan_synthase PF02364.10 ETS62858.1 - 0 1366.2 0.0 0 1365.9 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 ETS62858.1 - 3e-37 127.0 0.0 6.5e-37 126.0 0.0 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 ETS62859.1 - 2.2e-95 319.2 0.0 3.5e-95 318.6 0.0 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 ETS62859.1 - 4.7e-18 65.4 0.9 4.7e-18 65.4 0.6 1.8 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.13 ETS62859.1 - 5.8e-05 22.4 0.0 0.00023 20.4 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GyrI-like PF06445.10 ETS62860.1 - 0.04 13.9 0.0 2.2 8.3 0.0 2.3 1 1 1 2 2 2 0 GyrI-like small molecule binding domain DUF1762 PF08574.5 ETS62861.1 - 1.1e-05 25.7 6.2 1.1e-05 25.7 4.3 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1762) Ras PF00071.17 ETS62863.1 - 1.8e-54 183.5 0.0 2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS62863.1 - 2.7e-20 73.0 0.0 4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS62863.1 - 2e-07 30.3 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS62863.1 - 0.00024 20.6 0.1 0.0029 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS62863.1 - 0.00062 18.9 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS62863.1 - 0.0031 17.4 0.0 0.0062 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS62863.1 - 0.012 14.8 0.1 0.07 12.3 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 ETS62863.1 - 0.041 13.2 0.1 0.091 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 ETS62863.1 - 0.12 11.7 0.2 0.31 10.4 0.1 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-RING_3 PF14369.1 ETS62864.1 - 0.014 15.3 0.2 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 zinc-finger zf-C2H2 PF00096.21 ETS62864.1 - 0.081 13.3 18.1 0.08 13.3 1.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF605 PF04652.11 ETS62865.1 - 1.4e-103 347.2 2.8 2.3e-103 346.5 1.9 1.3 1 0 0 1 1 1 1 Vta1 like PDDEXK_2 PF12784.2 ETS62865.1 - 0.043 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase MCM PF00493.18 ETS62866.1 - 1.3e-133 444.9 0.0 1.8e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS62866.1 - 2.5e-19 69.9 0.0 1.2e-18 67.7 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 ETS62866.1 - 5.6e-08 32.6 0.0 2.1e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS62866.1 - 4.6e-07 29.2 0.0 0.00025 20.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETS62866.1 - 0.00039 20.0 0.1 0.028 14.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETS62866.1 - 0.0052 16.2 0.2 1.3 8.5 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain DSX_dimer PF08828.5 ETS62866.1 - 0.21 11.1 4.7 10 5.7 0.2 3.6 3 0 0 3 3 3 0 Doublesex dimerisation domain WD40 PF00400.27 ETS62867.1 - 3.1e-25 87.0 2.3 6.9e-06 25.7 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 ETS62867.1 - 1.6e-06 27.9 0.1 0.00013 21.6 0.1 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 ETS62867.1 - 0.00052 19.1 0.2 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 ETS62867.1 - 0.0018 16.2 0.3 0.25 9.0 0.2 2.6 2 1 0 2 2 2 2 IKI3 family Apc4_WD40 PF12894.2 ETS62867.1 - 0.023 14.2 0.0 8.3 5.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3512 PF12024.3 ETS62868.1 - 1.9e-05 24.0 0.2 4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) zf-CCCH PF00642.19 ETS62869.1 - 4.5e-17 61.2 15.2 6.3e-10 38.5 1.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETS62869.1 - 0.24 11.4 14.8 0.8 9.8 0.9 3.0 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type oligo_HPY PF08352.7 ETS62869.1 - 0.44 10.9 5.3 5.4 7.4 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region DUF2418 PF10332.4 ETS62870.1 - 8.1e-27 93.4 0.1 8.1e-27 93.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Ras PF00071.17 ETS62871.1 - 6.1e-62 207.7 0.1 7.3e-62 207.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS62871.1 - 6e-20 71.9 0.0 8.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS62871.1 - 1.7e-12 46.9 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS62871.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS62871.1 - 2.2e-05 23.9 0.1 9.1e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 ETS62871.1 - 7.1e-05 22.9 0.0 0.00027 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 ETS62871.1 - 0.0024 17.0 0.1 0.0059 15.7 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETS62871.1 - 0.0028 16.8 0.0 0.0057 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 ETS62871.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 ETS62871.1 - 0.017 15.1 0.4 0.042 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 ETS62871.1 - 0.023 14.1 0.0 0.077 12.4 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 ETS62871.1 - 0.025 13.7 0.0 0.061 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETS62871.1 - 0.028 14.7 0.2 0.036 14.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 ETS62871.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETS62871.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 ETS62871.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 ETS62871.1 - 0.13 11.5 0.1 0.67 9.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Xpo1 PF08389.7 ETS62872.1 - 1.3e-22 80.2 0.0 5.4e-21 75.0 0.0 3.4 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 ETS62872.1 - 7.1e-05 22.6 0.3 0.00021 21.1 0.2 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain MxiH PF09392.5 ETS62872.1 - 2.8 8.5 6.5 3.2 8.3 0.0 3.6 3 1 0 3 3 3 0 Type III secretion needle MxiH like AAA PF00004.24 ETS62873.1 - 2.6e-41 140.9 0.0 4.8e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETS62873.1 - 1.3e-28 98.6 0.2 5e-28 96.7 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 ETS62873.1 - 2.7e-23 81.6 5.4 8.5e-23 80.0 3.8 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 ETS62873.1 - 1.4e-05 25.2 0.4 0.0019 18.3 0.0 2.7 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 ETS62873.1 - 4.3e-05 23.0 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 ETS62873.1 - 4.9e-05 24.1 0.2 0.00022 22.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 ETS62873.1 - 6.1e-05 21.9 0.3 0.00012 20.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 ETS62873.1 - 6.7e-05 22.8 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS62873.1 - 7e-05 22.9 0.1 0.015 15.4 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.1 ETS62873.1 - 0.00013 21.9 0.4 0.00064 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS62873.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETS62873.1 - 0.00016 21.4 0.0 0.00056 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS62873.1 - 0.00025 21.1 0.4 0.0069 16.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 ETS62873.1 - 0.00066 19.1 0.1 0.24 10.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 ETS62873.1 - 0.0013 18.7 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 ETS62873.1 - 0.0018 17.2 0.0 0.0035 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 ETS62873.1 - 0.0087 15.2 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ETS62873.1 - 0.014 14.5 0.1 0.48 9.4 0.1 2.5 1 1 0 1 1 1 0 Zeta toxin KaiC PF06745.8 ETS62873.1 - 0.015 14.4 0.0 4.7 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 ETS62873.1 - 0.03 13.9 0.4 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 ETS62873.1 - 0.032 13.0 0.5 2.6 6.7 0.0 2.8 3 0 0 3 3 3 0 AFG1-like ATPase PhoH PF02562.11 ETS62873.1 - 0.058 12.6 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 ETS62873.1 - 0.063 13.0 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Sigma54_activat PF00158.21 ETS62873.1 - 0.069 12.6 0.0 0.51 9.8 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 ETS62873.1 - 0.075 12.6 0.0 0.59 9.7 0.0 2.4 2 1 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 ETS62873.1 - 0.095 12.7 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 ETS62873.1 - 0.41 10.0 1.9 0.79 9.0 0.0 2.3 3 1 0 4 4 4 0 AAA-like domain Vps39_2 PF10367.4 ETS62874.1 - 1.3e-10 41.3 0.2 3.9e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 ETS62874.1 - 0.0001 22.2 0.0 0.00072 19.5 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 ETS62874.1 - 0.025 13.9 0.0 0.12 11.7 0.0 2.0 1 1 0 1 1 1 0 CNH domain PQQ_3 PF13570.1 ETS62874.1 - 0.1 12.9 0.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain G6B PF15096.1 ETS62875.1 - 0.08 12.4 0.2 0.15 11.5 0.1 1.4 1 1 0 1 1 1 0 G6B family zf-C2H2 PF00096.21 ETS62876.1 - 2.2e-06 27.6 12.5 0.0026 17.9 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS62876.1 - 4.2e-06 26.7 14.3 0.0021 18.2 1.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS62876.1 - 0.018 15.3 10.8 0.2 11.9 1.9 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Terminase_GpA PF05876.7 ETS62876.1 - 1.1 7.4 6.5 1.6 6.9 4.5 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-C2H2_jaz PF12171.3 ETS62876.1 - 3.9 7.7 11.6 0.72 10.0 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.22 ETS62878.1 - 1.8e-59 197.4 1.0 2.1e-20 72.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.2 ETS62878.1 - 8.6 6.2 10.7 17 5.2 2.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Phage_coat PF09063.5 ETS62879.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phage PP7 coat protein Inositol_P PF00459.20 ETS62880.1 - 1.3e-54 185.3 0.3 1.5e-53 181.8 0.2 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.20 ETS62881.1 - 6.3e-66 222.1 0.0 9.3e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62881.1 - 3.4e-46 157.4 0.0 5.2e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LIM PF00412.17 ETS62881.1 - 4.6e-15 55.4 29.0 4e-10 39.6 1.7 3.9 4 0 0 4 4 4 3 LIM domain Kinase-like PF14531.1 ETS62881.1 - 2e-06 26.9 0.0 6e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETS62881.1 - 0.033 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras_bdg_2 PF14847.1 ETS62881.1 - 0.18 11.7 0.0 0.5 10.3 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Seadorna_VP7 PF07387.6 ETS62881.1 - 2.5 6.8 0.0 3.9 6.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 PCI PF01399.22 ETS62884.1 - 1.2e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain LIP PF03583.9 ETS62887.1 - 2.7e-71 240.1 0.2 3.7e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 ETS62887.1 - 0.054 13.3 0.9 0.18 11.6 0.6 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2413 PF10310.4 ETS62888.1 - 5.1e-82 276.0 3.5 7e-82 275.5 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Pol_alpha_B_N PF08418.5 ETS62888.1 - 1.6 8.1 9.5 2.9 7.3 6.6 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Sugar_tr PF00083.19 ETS62889.1 - 5.2e-56 190.1 16.9 3.9e-55 187.2 11.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS62889.1 - 2.2e-16 59.5 24.8 2.2e-16 59.5 17.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3437 PF11919.3 ETS62890.1 - 6.8e-32 109.0 0.0 5.9e-31 106.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 ETS62890.1 - 0.00015 21.5 0.1 0.0015 18.4 0.1 2.9 2 0 0 2 2 2 1 HEAT repeat DUF1546 PF07571.8 ETS62890.1 - 0.002 18.2 0.2 0.096 12.8 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1546) Arm PF00514.18 ETS62890.1 - 0.0022 17.7 0.1 0.011 15.5 0.1 2.3 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS62890.1 - 0.0059 16.8 2.6 0.016 15.4 0.0 3.1 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 ETS62890.1 - 0.012 16.0 0.0 0.1 13.1 0.0 2.8 1 0 0 1 1 1 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETS62890.1 - 0.089 13.1 0.1 0.48 10.8 0.1 2.3 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cut8_C PF08559.5 ETS62891.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Cut8 six-helix bundle Pkinase PF00069.20 ETS62893.1 - 2.5e-73 246.4 0.0 2.9e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS62893.1 - 1.8e-35 122.2 0.0 2.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS62893.1 - 0.0085 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS62893.1 - 0.039 13.6 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS62893.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Utp12 PF04003.7 ETS62894.1 - 5.8e-12 45.4 0.4 1.6e-11 44.0 0.2 1.8 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 ETS62894.1 - 4.2 7.4 13.3 0.14 12.1 1.2 3.4 3 1 0 3 3 3 0 WD domain, G-beta repeat CoA_binding PF02629.14 ETS62895.1 - 1e-27 96.4 0.4 3.5e-27 94.7 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 ETS62895.1 - 5.6e-20 71.5 0.2 1.1e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 ETS62895.1 - 2.4e-08 33.6 0.1 5.5e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 ETS62895.1 - 4.8e-05 23.5 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 ETS62895.1 - 0.0022 18.4 0.0 0.0096 16.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold HNH_3 PF13392.1 ETS62896.1 - 7.6e-05 22.0 0.3 0.00011 21.4 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease TAP_C PF03943.8 ETS62897.1 - 5.4e-14 51.3 0.2 1.1e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 ETS62897.1 - 5.6e-07 29.0 7.1 5.2e-05 22.7 0.9 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS62897.1 - 0.0012 18.5 0.9 0.0045 16.7 0.3 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.1 ETS62897.1 - 0.054 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat NTF2 PF02136.15 ETS62897.1 - 0.088 13.1 0.1 1.5 9.1 0.1 2.4 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain TGS PF02824.16 ETS62898.1 - 1.9e-18 66.0 0.1 3.6e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 ETS62898.1 - 1.5e-17 63.6 0.0 3.7e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS62898.1 - 6.9e-12 44.9 0.0 1.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 ETS62898.1 - 1.7e-06 28.4 0.0 4.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 ETS62898.1 - 0.0015 18.3 0.4 0.28 10.9 0.0 2.5 1 1 0 2 2 2 2 Dynamin family AIG1 PF04548.11 ETS62898.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family CBS PF00571.23 ETS62899.1 - 2.5e-36 123.2 9.2 1.3e-08 34.4 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 ETS62899.1 - 2.1e-06 27.2 0.0 4.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain DUF4288 PF14119.1 ETS62899.1 - 0.055 13.6 0.0 8.1 6.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) DUF2380 PF09533.5 ETS62899.1 - 0.073 12.4 0.8 14 5.0 0.0 2.8 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) NYN PF01936.13 ETS62899.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 NYN domain DUF1682 PF07946.9 ETS62899.1 - 9.5 4.9 7.9 20 3.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Zn_clus PF00172.13 ETS62900.1 - 3.6e-06 26.7 11.3 6.7e-06 25.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCAS2 PF05700.6 ETS62902.1 - 2e-62 210.5 1.1 2.7e-62 210.1 0.8 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Erythro-docking PF09277.6 ETS62902.1 - 0.025 14.2 1.5 0.6 9.8 0.2 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking Nup54 PF13874.1 ETS62902.1 - 0.49 10.0 10.6 1.3 8.6 6.0 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Enkurin PF13864.1 ETS62902.1 - 0.51 10.5 9.2 0.44 10.7 4.9 1.9 2 0 0 2 2 2 0 Calmodulin-binding IncA PF04156.9 ETS62902.1 - 1.1 8.8 11.0 2.1 7.8 7.7 1.4 1 0 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 ETS62902.1 - 5.4 7.3 6.8 10 6.4 0.9 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Complex1_30kDa PF00329.14 ETS62903.1 - 6.6e-35 119.4 0.0 9.4e-35 118.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Arm PF00514.18 ETS62904.1 - 6.8e-09 35.2 24.5 5.1e-06 26.1 0.2 8.4 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 ETS62904.1 - 2.5e-05 23.9 20.6 0.16 12.1 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat Phage_tail PF04630.7 ETS62904.1 - 0.27 10.2 0.0 0.89 8.6 0.0 1.7 2 0 0 2 2 2 0 Phage major tail protein HEAT_EZ PF13513.1 ETS62904.1 - 0.39 11.2 25.0 2.2 8.8 0.0 8.1 7 2 0 7 7 7 0 HEAT-like repeat MCM PF00493.18 ETS62905.1 - 8.3e-129 429.1 0.0 1.3e-128 428.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS62905.1 - 2.3e-18 66.8 0.1 7.1e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS62905.1 - 6.7e-08 31.9 0.0 8.8e-07 28.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETS62905.1 - 0.0045 16.5 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETS62905.1 - 0.0071 15.8 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain BTV_NS2 PF04514.7 ETS62905.1 - 0.16 10.7 2.3 1.1 8.0 1.6 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DUF4611 PF15387.1 ETS62905.1 - 3.7 7.7 7.5 2.6 8.2 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4225 PF13988.1 ETS62906.1 - 0.22 10.9 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DUF500 PF04366.7 ETS62907.1 - 3.9e-38 129.7 0.6 3.9e-38 129.7 0.4 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 ETS62907.1 - 3.1e-12 45.6 0.1 6.1e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS62907.1 - 4.4e-11 42.0 0.0 8.4e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 ETS62907.1 - 9.6e-11 41.1 0.0 1.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rad60-SLD PF11976.3 ETS62908.1 - 0.079 12.6 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UvrD_C PF13361.1 ETS62909.1 - 2e-74 251.1 0.0 1.3e-43 149.8 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 ETS62909.1 - 5.3e-69 232.9 0.0 1.2e-68 231.7 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 ETS62909.1 - 9.5e-13 48.1 0.0 3.2e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 ETS62909.1 - 1.3e-10 40.8 0.2 5.2e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 ETS62909.1 - 1e-05 25.2 0.1 3.1e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS62909.1 - 0.0085 15.6 0.3 1.7 8.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vhr1 PF04001.8 ETS62909.1 - 0.056 13.3 0.1 20 5.1 0.1 3.0 2 0 0 2 2 2 0 Transcription factor Vhr1 PALP PF00291.20 ETS62910.1 - 6.4e-48 163.5 3.9 8.1e-48 163.2 2.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU PF00009.22 ETS62911.1 - 2.7e-50 170.4 0.0 4.8e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 ETS62911.1 - 4.1e-22 77.8 0.0 9.7e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 ETS62911.1 - 6.3e-17 61.2 0.3 1.5e-14 53.5 0.2 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS62911.1 - 5.7e-08 32.7 0.0 2e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS62911.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 ETS62911.1 - 0.072 12.6 0.1 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G, domain IV HCO3_cotransp PF00955.16 ETS62912.1 - 9.3e-42 143.3 10.3 1.1e-23 83.6 0.9 3.0 1 1 1 2 2 2 2 HCO3- transporter family FHA PF00498.21 ETS62913.1 - 0.041 14.0 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 FHA domain Cwf_Cwc_15 PF04889.7 ETS62913.1 - 9.2 5.9 10.8 0.14 11.8 2.0 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TMEM247 PF15444.1 ETS62914.1 - 0.074 12.8 3.1 0.12 12.1 1.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 247 AMP-binding PF00501.23 ETS62915.1 - 5e-77 259.0 0.1 6.8e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS62915.1 - 5.9e-64 215.3 0.0 1.1e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 ETS62915.1 - 2.9e-14 53.0 0.0 8.7e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS62915.1 - 5.8e-09 36.7 0.0 3e-08 34.4 0.0 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 ETS62915.1 - 6.7e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.15 ETS62915.1 - 7.3e-05 21.7 0.2 0.0011 17.9 0.2 2.2 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.14 ETS62915.1 - 0.026 13.2 0.0 3 6.4 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1688 PF07958.6 ETS62917.1 - 2.4e-161 536.9 0.0 3.1e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) ABC2_membrane PF01061.19 ETS62918.1 - 1.2e-33 116.0 16.4 1.2e-33 116.0 11.4 2.2 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.22 ETS62918.1 - 9.1e-25 87.5 0.0 1.5e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS62918.1 - 1.7e-06 28.2 0.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 ETS62918.1 - 7.5e-06 25.2 19.1 7.5e-06 25.2 13.2 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 ETS62918.1 - 0.00049 19.5 0.0 0.0065 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS62918.1 - 0.0062 16.0 0.1 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS62918.1 - 0.012 16.4 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS62918.1 - 0.014 14.6 0.0 0.04 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS62918.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain hEGF PF12661.2 ETS62918.1 - 0.018 15.1 20.2 0.47 10.6 3.0 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF AAA_28 PF13521.1 ETS62918.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS62918.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 ETS62918.1 - 0.069 12.5 0.1 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 ETS62918.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 ETS62918.1 - 0.094 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 ETS62918.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 ETS62918.1 - 0.13 11.2 0.0 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 ETS62918.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 ETS62918.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 ETS62918.1 - 0.29 10.3 0.0 0.51 9.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.1 ETS62918.1 - 0.31 11.3 0.1 0.52 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.2 ETS62920.1 - 2.8e-26 90.6 6.7 2.4e-06 27.0 0.8 8.0 5 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS62920.1 - 1.1e-23 82.7 15.2 2.7e-07 30.2 0.4 6.3 5 1 1 6 6 6 3 Leucine rich repeat Hemerythrin PF01814.18 ETS62920.1 - 7.3e-12 45.5 2.2 4.3e-11 43.1 1.4 2.4 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LRR_1 PF00560.28 ETS62920.1 - 1.8e-09 36.3 20.6 0.4 10.8 0.3 11.2 10 4 2 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 ETS62920.1 - 1.8e-06 27.2 18.4 4.8 7.8 0.0 9.5 9 0 0 9 9 9 2 Leucine rich repeat LRR_9 PF14580.1 ETS62920.1 - 0.0075 15.8 2.6 8.7 5.8 0.0 3.5 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 ETS62920.1 - 0.023 14.7 13.2 2.4 8.5 0.2 6.6 7 1 1 8 8 8 0 Leucine Rich repeat MAP65_ASE1 PF03999.7 ETS62921.1 - 5.1e-55 187.2 0.0 1.3e-48 166.0 0.0 2.1 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF1192 PF06698.6 ETS62921.1 - 0.23 11.2 4.1 3.8 7.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Baculo_PEP_C PF04513.7 ETS62921.1 - 0.41 10.4 3.4 0.39 10.5 0.1 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 ETS62921.1 - 7.8 6.9 9.0 29 5.1 0.1 4.4 5 0 0 5 5 5 0 SlyX HrpB7 PF09486.5 ETS62921.1 - 9.6 6.1 12.9 7.1 6.5 1.8 3.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) PGP_phosphatase PF09419.5 ETS62922.1 - 6.4e-50 168.7 0.0 1.1e-45 154.9 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase IL6 PF00489.12 ETS62922.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Lum_binding PF00677.12 ETS62926.1 - 1.3e-30 105.0 0.1 7.9e-20 70.5 0.1 3.6 3 1 0 3 3 3 3 Lumazine binding domain Homoserine_dh PF00742.14 ETS62927.1 - 1.2e-45 155.4 0.0 1.7e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 ETS62927.1 - 3e-14 53.3 0.0 5.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 ETS62927.1 - 0.14 12.4 1.1 1.6 9.0 0.8 2.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain BUD22 PF09073.5 ETS62928.1 - 6.5e-86 289.0 44.9 6.5e-86 289.0 31.1 2.6 2 1 0 2 2 2 1 BUD22 PP1_inhibitor PF05361.7 ETS62928.1 - 1.8 8.2 8.5 0.054 13.1 0.7 2.4 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor GMC_oxred_N PF00732.14 ETS62929.1 - 5.3e-58 196.5 0.0 7.8e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS62929.1 - 9e-37 126.5 0.3 1.8e-36 125.6 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_M20 PF01546.23 ETS62929.1 - 1.5e-25 89.8 0.1 4e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DAO PF01266.19 ETS62929.1 - 2e-05 23.6 1.9 2e-05 23.6 1.3 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Peptidase_M28 PF04389.12 ETS62929.1 - 7.7e-05 22.4 0.0 0.00024 20.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 ETS62929.1 - 9.8e-05 22.0 0.0 0.00049 19.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Lycopene_cycl PF05834.7 ETS62929.1 - 0.0011 17.9 0.0 0.0026 16.7 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS62929.1 - 0.0038 17.2 1.4 0.015 15.2 0.9 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS62929.1 - 0.013 14.6 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 ETS62929.1 - 0.054 13.3 0.6 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS62929.1 - 0.098 12.7 0.5 1.5 8.8 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Antimicrobial_5 PF08026.6 ETS62929.1 - 0.18 11.6 0.4 0.48 10.3 0.3 1.7 1 0 0 1 1 1 0 Bee antimicrobial peptide FAD_binding_2 PF00890.19 ETS62929.1 - 0.36 9.6 4.4 0.73 8.6 3.1 1.5 1 0 0 1 1 1 0 FAD binding domain DLH PF01738.13 ETS62930.1 - 1e-19 70.6 0.4 1.2e-19 70.4 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS62930.1 - 0.00034 20.3 0.3 0.00065 19.4 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PspB PF06667.7 ETS62931.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF3609 PF12259.3 ETS62931.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Herpes_gE PF02480.11 ETS62931.1 - 0.16 10.2 0.0 0.16 10.2 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pyr_redox_3 PF13738.1 ETS62932.1 - 3.5e-30 105.5 0.0 1.4e-29 103.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS62932.1 - 2e-17 62.5 0.0 2.6e-15 55.6 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS62932.1 - 2.3e-10 40.3 0.0 1.2e-08 34.7 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS62932.1 - 1.9e-07 30.3 0.1 2.1e-06 26.9 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 ETS62932.1 - 2e-05 24.8 0.2 0.0087 16.4 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS62932.1 - 0.00025 20.2 0.0 0.00058 19.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 ETS62932.1 - 0.0012 18.7 0.5 0.042 13.7 0.4 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS62932.1 - 0.0061 15.5 0.1 1.4 7.7 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 ETS62932.1 - 0.017 14.0 0.4 0.12 11.3 0.0 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS62932.1 - 0.02 14.6 0.3 8.2 6.1 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS62932.1 - 0.031 13.1 0.1 0.15 10.8 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 ETS62932.1 - 0.085 12.9 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 ETS62932.1 - 0.089 11.8 0.0 7.1 5.5 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Amidohydro_4 PF13147.1 ETS62933.1 - 5.2e-14 52.9 0.4 3.8e-13 50.1 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS62933.1 - 7.7e-12 45.4 0.0 6.5e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS62933.1 - 9.1e-06 25.4 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS62933.1 - 1.9e-05 24.1 0.0 5.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family DUF3605 PF12239.3 ETS62934.1 - 1.6e-29 102.7 0.0 1.6e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) Med25_VWA PF11265.3 ETS62934.1 - 0.0029 16.6 0.0 0.0041 16.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A BcrAD_BadFG PF01869.15 ETS62936.1 - 2.2e-10 40.2 0.0 4e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Glucosamine_iso PF01182.15 ETS62937.1 - 2.6e-24 86.0 0.0 4.2e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Zn_clus PF00172.13 ETS62938.1 - 1.3e-06 28.1 9.0 1.3e-06 28.1 6.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PGM_PMM_I PF02878.11 ETS62939.1 - 4.1e-35 120.2 0.0 6.9e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 ETS62939.1 - 1.1e-16 61.0 0.0 3.2e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 ETS62939.1 - 4.2e-11 42.8 0.0 8.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 ETS62939.1 - 1.3e-08 34.7 0.0 4.2e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Lipase_3 PF01764.20 ETS62940.1 - 2.7e-12 46.4 0.9 5.2e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF1479 PF07350.7 ETS62941.1 - 6.5e-144 479.4 0.0 7.7e-144 479.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 ETS62941.1 - 0.0035 17.3 0.3 3.6 7.5 0.0 2.9 3 0 0 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 ETS62942.1 - 4.3e-53 180.4 0.0 5.7e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APS_kinase PF01583.15 ETS62945.1 - 1.5e-69 232.6 0.0 1.8e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 ETS62945.1 - 9.8e-07 28.7 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS62945.1 - 1.1e-05 26.2 0.0 2.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS62945.1 - 1.1e-05 25.7 0.1 2.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 ETS62945.1 - 8.7e-05 21.8 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 ETS62945.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 ETS62945.1 - 0.0033 16.5 0.0 0.013 14.5 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 ETS62945.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 ETS62945.1 - 0.061 13.6 0.3 0.069 13.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS62945.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 ETS62945.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 ETS62945.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 ETS62945.1 - 0.15 11.6 0.1 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MaoC_dehydrat_N PF13452.1 ETS62946.1 - 2.1e-08 34.0 0.1 6.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.14 ETS62946.1 - 0.00044 19.6 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain SelR PF01641.13 ETS62947.1 - 1.3e-50 170.2 0.2 1.7e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 SelR domain WD40 PF00400.27 ETS62948.1 - 6.3e-17 60.7 13.2 2.4e-08 33.5 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Phage_holin PF04688.8 ETS62948.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Phage lysis protein, holin PQQ_3 PF13570.1 ETS62948.1 - 0.073 13.3 0.4 60 4.1 0.1 4.1 4 0 0 4 4 4 0 PQQ-like domain MAP65_ASE1 PF03999.7 ETS62948.1 - 2.8 6.4 9.9 4 5.9 6.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) WD40 PF00400.27 ETS62949.1 - 1.2e-06 28.1 9.2 0.075 12.9 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat MBOAT_2 PF13813.1 ETS62950.1 - 5.1e-09 36.0 0.9 4.4e-07 29.8 0.6 2.6 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DEAD PF00270.24 ETS62951.1 - 6.6e-45 152.6 0.0 1.4e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS62951.1 - 1.3e-27 95.5 0.0 4.8e-26 90.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS62951.1 - 0.0009 19.1 0.0 0.0009 19.1 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 ETS62951.1 - 0.0019 17.3 0.0 0.0019 17.3 0.0 3.3 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit TFIIF_alpha PF05793.7 ETS62951.1 - 0.45 8.8 21.9 0.64 8.3 15.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.6 ETS62951.1 - 1.6 6.5 9.7 2.1 6.1 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2413 PF10310.4 ETS62951.1 - 2.7 6.7 15.6 4.1 6.1 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ycf1 PF05758.7 ETS62951.1 - 3.6 5.1 5.8 4.5 4.8 4.0 1.1 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.11 ETS62951.1 - 9.9 5.0 7.6 19 4.1 5.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit adh_short PF00106.20 ETS62952.1 - 1.4e-12 47.8 0.0 1.2e-11 44.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS62952.1 - 3.8e-06 26.8 0.2 3.8e-05 23.5 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS62952.1 - 0.00017 21.3 0.0 0.0013 18.4 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 ETS62952.1 - 0.0013 18.8 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding EF-hand_5 PF13202.1 ETS62953.1 - 0.16 11.3 0.5 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 EF hand Ras PF00071.17 ETS62954.1 - 1.1e-52 177.7 0.0 1.3e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS62954.1 - 1.3e-18 67.6 0.0 1.8e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS62954.1 - 2.9e-11 42.9 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS62954.1 - 2.2e-06 27.2 0.0 3.4e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS62954.1 - 2.9e-05 23.3 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS62954.1 - 0.00087 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETS62954.1 - 0.0034 17.5 0.0 0.0053 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS62954.1 - 0.005 16.8 0.1 0.0079 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 ETS62954.1 - 0.0098 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit KaiC PF06745.8 ETS62954.1 - 0.015 14.4 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 ETS62954.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 ETS62954.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 ETS62954.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 ETS62954.1 - 0.095 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 ETS62954.1 - 0.099 12.1 0.0 2.1 7.8 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RWD PF05773.17 ETS62955.1 - 3.4e-19 68.8 0.1 8.6e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 RWD domain DUF445 PF04286.7 ETS62955.1 - 1.1 8.7 8.2 2.2 7.7 5.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) HlyIII PF03006.15 ETS62956.1 - 3.5e-56 190.0 16.7 3.5e-56 190.0 11.5 2.3 2 1 0 2 2 2 1 Haemolysin-III related EBP PF05241.7 ETS62956.1 - 3.8e-07 29.3 9.3 3.8e-07 29.3 6.4 2.4 2 0 0 2 2 2 1 Emopamil binding protein GWT1 PF06423.7 ETS62956.1 - 0.36 10.9 6.5 0.52 10.3 0.3 2.7 2 0 0 2 2 2 0 GWT1 PAT1 PF09770.4 ETS62958.1 - 0.36 9.0 17.4 0.46 8.6 12.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_5 PF12695.2 ETS62960.1 - 3e-08 33.5 0.0 3e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS62960.1 - 1.7e-07 31.3 0.4 3.7e-07 30.2 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cyt-b5 PF00173.23 ETS62961.1 - 9.5e-22 76.5 0.1 1e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Init_tRNA_PT PF04179.7 ETS62962.1 - 2.3e-104 349.7 0.0 9.9e-102 341.1 0.0 2.0 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase HORMA PF02301.13 ETS62963.1 - 3.5e-11 42.9 0.0 6.6e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 HORMA domain zf-CCCH_2 PF14608.1 ETS62964.1 - 0.02 14.8 2.4 1.6 8.8 0.1 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 ETS62964.1 - 0.03 13.9 9.6 0.2 11.3 0.9 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) E1-E2_ATPase PF00122.15 ETS62965.1 - 2.8e-66 222.8 3.6 5e-66 222.0 2.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS62965.1 - 1.6e-35 122.2 4.0 1.6e-35 122.2 2.8 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS62965.1 - 7.9e-30 104.8 2.6 2.6e-24 86.8 0.3 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS62965.1 - 9.2e-17 60.7 0.0 1.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS62965.1 - 7.8e-14 52.2 0.2 2e-13 50.9 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS62965.1 - 5.9e-13 48.0 0.0 1.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS62965.1 - 0.0004 20.0 0.9 0.0059 16.2 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DctM PF06808.7 ETS62965.1 - 0.0017 16.9 0.1 0.0017 16.9 0.1 2.2 3 0 0 3 3 3 1 DctM-like transporters ABC_tran PF00005.22 ETS62966.1 - 9.1e-50 168.5 0.0 4.5e-30 104.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS62966.1 - 5.4e-24 85.0 31.5 8.7e-17 61.4 3.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_25 PF13481.1 ETS62966.1 - 4.1e-08 32.8 0.1 0.0002 20.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 ETS62966.1 - 2.1e-07 31.2 0.0 0.041 13.8 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS62966.1 - 5.4e-07 29.7 3.0 0.0017 18.3 0.2 3.9 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 ETS62966.1 - 5.9e-07 28.9 4.6 0.015 14.5 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS62966.1 - 1.9e-05 24.0 0.6 0.02 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS62966.1 - 3e-05 24.1 0.9 0.6 10.2 0.0 3.4 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS62966.1 - 0.00018 20.7 0.2 0.079 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 ETS62966.1 - 0.00083 19.8 0.0 0.76 10.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 ETS62966.1 - 0.0038 16.9 3.0 0.24 11.1 0.1 4.0 3 0 0 3 3 3 1 Part of AAA domain NACHT PF05729.7 ETS62966.1 - 0.0065 16.1 1.3 0.36 10.4 0.2 3.0 3 0 0 3 3 3 1 NACHT domain MobB PF03205.9 ETS62966.1 - 0.013 15.2 0.5 0.82 9.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 ETS62966.1 - 0.015 14.7 2.3 1.3 8.3 0.5 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 ETS62966.1 - 0.025 14.9 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETS62966.1 - 0.025 14.5 0.1 13 5.7 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 ETS62966.1 - 0.028 13.8 0.3 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 ETS62966.1 - 0.052 13.3 0.4 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 ETS62966.1 - 0.065 14.0 0.0 7.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 ETS62966.1 - 0.086 12.2 0.1 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pox_A32 PF04665.7 ETS62966.1 - 0.12 11.6 1.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.1 ETS62966.1 - 0.15 12.4 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain MaoC_dehydratas PF01575.14 ETS62967.1 - 3.6e-26 90.9 0.0 1.1e-25 89.3 0.0 1.9 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 ETS62967.1 - 4.3e-11 42.7 0.0 1.4e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase BAR PF03114.13 ETS62968.1 - 1.7e-42 145.5 6.5 2.3e-42 145.0 4.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 ETS62968.1 - 5.5e-15 54.4 0.1 1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS62968.1 - 1.4e-14 53.4 0.1 2.5e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS62968.1 - 3.9e-12 45.4 0.0 7.1e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.6 ETS62968.1 - 0.00059 19.2 1.2 0.00086 18.6 0.9 1.2 1 0 0 1 1 1 1 FAM92 protein Prefoldin PF02996.12 ETS62968.1 - 0.064 12.9 1.6 0.11 12.2 0.1 2.1 2 1 1 3 3 3 0 Prefoldin subunit T4SS PF07996.6 ETS62968.1 - 0.17 11.7 2.3 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion system proteins Vps5 PF09325.5 ETS62968.1 - 0.33 10.1 6.5 1.3 8.2 4.5 2.2 1 1 0 1 1 1 0 Vps5 C terminal like PBP1_TM PF14812.1 ETS62969.1 - 0.72 10.2 5.0 0.46 10.8 1.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ebola_NP PF05505.7 ETS62969.1 - 3.4 5.6 6.8 5.9 4.8 4.7 1.4 1 0 0 1 1 1 0 Ebola nucleoprotein Glyco_hydro_43 PF04616.9 ETS62970.1 - 5.1e-17 61.8 0.3 8e-17 61.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1295 PF06966.7 ETS62971.1 - 5e-52 176.5 0.4 6.7e-52 176.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 ETS62971.1 - 0.00011 22.2 0.1 0.00055 20.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 ETS62971.1 - 0.002 17.8 2.4 0.0028 17.4 0.0 2.1 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 ETS62971.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltransf_16 PF10294.4 ETS62972.1 - 1.3e-14 53.9 0.0 1.5e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 ETS62972.1 - 0.0013 19.2 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS62972.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Metallopep PF12044.3 ETS62973.1 - 2.3e-93 312.9 0.0 1.5e-72 244.3 0.0 2.1 2 0 0 2 2 2 2 Putative peptidase family Jacalin PF01419.12 ETS62973.1 - 0.0068 16.2 0.0 0.11 12.3 0.0 2.3 1 1 1 2 2 2 1 Jacalin-like lectin domain Peptidase_M66 PF10462.4 ETS62973.1 - 0.066 12.0 0.2 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Aldo_ket_red PF00248.16 ETS62974.1 - 3.6e-56 190.0 0.0 4.2e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Toxin_51 PF15531.1 ETS62974.1 - 0.026 14.3 0.2 1.4 8.7 0.0 2.7 2 1 0 2 2 2 0 Putative toxin 51 YflT PF11181.3 ETS62974.1 - 0.031 14.4 0.2 2.4 8.3 0.1 2.9 3 0 0 3 3 3 0 Heat induced stress protein YflT Tox-URI2 PF15653.1 ETS62974.1 - 0.093 12.9 0.4 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 URI fold toxin 2 DUF2256 PF10013.4 ETS62975.1 - 2.5e-13 49.5 3.2 4.4e-13 48.7 2.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.2 ETS62975.1 - 0.013 14.8 0.3 0.028 13.6 0.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Aldose_epim PF01263.15 ETS62976.1 - 8.5e-29 100.6 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Xan_ur_permease PF00860.15 ETS62978.1 - 6.1e-26 90.8 29.1 7e-26 90.6 17.7 2.3 2 1 0 2 2 2 1 Permease family ABC_tran PF00005.22 ETS62980.1 - 1.6e-50 170.9 1.0 2.7e-28 98.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS62980.1 - 2.5e-28 99.2 29.1 3.5e-20 72.5 4.7 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS62980.1 - 1.1e-09 37.9 6.2 0.0015 17.8 0.1 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS62980.1 - 3.7e-09 36.9 0.0 0.32 10.9 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 ETS62980.1 - 3.9e-07 29.5 0.6 0.039 13.4 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 ETS62980.1 - 6.9e-06 25.5 0.2 0.054 12.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS62980.1 - 1.3e-05 24.4 0.0 0.05 12.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 ETS62980.1 - 4.4e-05 23.0 1.1 0.43 9.9 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 ETS62980.1 - 8.2e-05 22.7 0.4 0.44 10.6 0.3 3.3 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 ETS62980.1 - 0.00034 21.0 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 ETS62980.1 - 0.00052 19.5 0.0 0.9 8.9 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 ETS62980.1 - 0.0012 18.8 0.8 0.03 14.3 0.3 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 ETS62980.1 - 0.0022 17.9 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 ETS62980.1 - 0.01 16.1 0.0 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 ETS62980.1 - 0.046 13.6 0.6 1.8 8.4 0.0 3.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 ETS62980.1 - 0.053 13.3 0.0 14 5.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 ETS62980.1 - 0.063 12.9 0.2 12 5.5 0.0 3.0 3 0 0 3 3 3 0 NTPase Dynamin_N PF00350.18 ETS62980.1 - 0.078 12.7 0.2 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ABC_ATPase PF09818.4 ETS62980.1 - 0.087 11.3 3.7 0.33 9.4 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NB-ARC PF00931.17 ETS62980.1 - 0.14 10.9 0.5 7.4 5.3 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.14 ETS62980.1 - 0.19 11.1 0.7 3.5 7.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 ETS62980.1 - 0.23 10.4 0.0 8.8 5.2 0.0 2.3 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.7 ETS62980.1 - 0.54 9.5 2.3 0.41 9.8 0.2 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein MARVEL PF01284.18 ETS62981.1 - 2.2e-08 34.0 6.7 3.2e-08 33.4 4.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DctQ PF04290.7 ETS62981.1 - 1.2 8.9 9.2 0.43 10.3 1.0 2.4 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Cmc1 PF08583.5 ETS62982.1 - 3.9e-13 48.9 0.7 4.6e-13 48.7 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 ETS62982.1 - 6.1e-05 22.3 0.7 8.5e-05 21.8 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PCI_Csn8 PF10075.4 ETS62982.1 - 0.053 13.2 0.0 0.078 12.7 0.0 1.5 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 Pet191_N PF10203.4 ETS62982.1 - 0.11 12.5 0.3 2.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF2237 PF09996.4 ETS62983.1 - 1.2e-31 108.6 0.0 2.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) LRR_8 PF13855.1 ETS62983.1 - 1.6e-13 50.2 32.1 1.4e-09 37.5 3.9 4.1 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 ETS62983.1 - 4.3e-12 45.3 26.3 1.3e-06 27.8 1.0 5.9 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS62983.1 - 0.00021 20.8 30.5 1.1 9.5 0.2 7.8 8 1 1 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.1 ETS62983.1 - 0.0013 18.3 0.4 0.038 13.5 0.3 2.5 3 0 0 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 ETS62983.1 - 0.6 10.5 29.8 3.8 8.1 0.2 8.3 9 0 0 9 9 9 0 Leucine rich repeat LRR_6 PF13516.1 ETS62983.1 - 3.9 7.8 20.5 7.2 7.0 1.7 6.0 5 1 1 6 6 6 0 Leucine Rich repeat AA_permease_2 PF13520.1 ETS62984.1 - 1.8e-60 204.7 38.1 2.2e-60 204.4 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS62984.1 - 5.1e-28 97.6 34.7 6.4e-28 97.3 24.0 1.1 1 0 0 1 1 1 1 Amino acid permease Corona_nucleoca PF00937.13 ETS62984.1 - 0.15 10.9 0.3 0.23 10.3 0.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FDF PF09532.5 ETS62985.1 - 1.8e-05 25.2 0.1 0.00011 22.7 0.0 2.2 2 0 0 2 2 2 1 FDF domain DUF4140 PF13600.1 ETS62985.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) NUDIX PF00293.23 ETS62986.1 - 1e-12 47.8 0.0 3e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DnaJ PF00226.26 ETS62987.1 - 1e-24 86.0 1.4 1.8e-24 85.2 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 ETS62987.1 - 2e-20 72.4 0.1 5.4e-19 67.8 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETS62987.1 - 1.5e-13 50.5 19.1 2.4e-13 49.8 13.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 ETS62987.1 - 0.0066 16.7 10.2 0.014 15.7 6.7 1.8 1 1 1 2 2 2 2 Cytochrome c3 Stc1 PF12898.2 ETS62987.1 - 0.12 12.4 12.2 0.78 9.8 2.8 2.3 1 1 1 2 2 2 0 Stc1 domain Cytochrome_C7 PF14522.1 ETS62987.1 - 3.9 7.1 13.6 20 4.8 9.4 2.1 1 1 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 ETS62987.1 - 5.9 6.6 13.1 0.97 9.1 2.7 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 ETS62987.1 - 8.6 6.7 8.1 2.2 8.6 2.2 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar DcpS PF05652.7 ETS62988.1 - 4.6e-29 101.0 0.0 9.1e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 ETS62988.1 - 4.3e-27 94.6 0.3 8.1e-27 93.7 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 ETS62988.1 - 0.017 15.6 0.2 0.046 14.2 0.2 1.8 1 0 0 1 1 1 0 HIT domain DHBP_synthase PF00926.14 ETS62989.1 - 0.049 12.8 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase FAP PF07174.6 ETS62989.1 - 0.067 12.4 7.8 0.1 11.8 5.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TFIIA PF03153.8 ETS62989.1 - 0.54 10.1 10.8 0.66 9.8 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2638 PF10937.3 ETS62989.1 - 4.6 8.3 8.1 5.5 8.0 4.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) DUF3235 PF11574.3 ETS62989.1 - 5.3 7.3 10.8 5e+02 1.0 7.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) Glyco_hydro_85 PF03644.8 ETS62990.1 - 2.9e-93 312.4 0.0 4.1e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 IU_nuc_hydro PF01156.14 ETS62991.1 - 1.3e-58 198.7 0.0 2.1e-58 198.0 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mito_carr PF00153.22 ETS62991.1 - 3.1e-48 161.4 4.6 1.1e-16 60.3 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Transthyretin PF00576.16 ETS62992.1 - 1e-32 112.3 0.0 1.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 ETS62992.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain PQ-loop PF04193.9 ETS62994.1 - 1.1e-23 82.5 1.3 9.9e-12 44.2 0.5 2.4 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.13 ETS62994.1 - 0.099 13.1 4.3 0.18 12.3 3.0 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor Polysacc_synt_C PF14667.1 ETS62994.1 - 3 7.6 11.8 2.9 7.6 4.0 2.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain SNase PF00565.12 ETS62995.1 - 8.5e-21 74.2 1.2 4.6e-09 36.5 0.6 3.3 1 1 1 2 2 2 2 Staphylococcal nuclease homologue GFO_IDH_MocA PF01408.17 ETS62996.1 - 6.3e-15 55.7 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS62996.1 - 9.1e-13 48.0 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_92 PF07971.7 ETS62997.1 - 5.1e-156 520.2 0.0 6.7e-156 519.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF1275 PF06912.6 ETS62998.1 - 6.9e-18 64.6 18.1 1.6e-17 63.3 12.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1275) DUF46 PF01864.12 ETS62998.1 - 0.021 14.6 0.2 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 DUF418 PF04235.7 ETS62998.1 - 0.037 13.6 3.7 3.6 7.2 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF418) EIID-AGA PF03613.9 ETS62998.1 - 0.59 9.0 5.9 0.7 8.7 0.3 2.6 1 1 1 2 2 2 0 PTS system mannose/fructose/sorbose family IID component Aldose_epim PF01263.15 ETS62999.1 - 1.1e-60 205.3 0.2 1.3e-60 205.0 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase CoA_binding_2 PF13380.1 ETS63000.1 - 2.3e-26 92.2 0.1 3.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Herpes_gp2 PF05955.6 ETS63000.1 - 0.059 12.6 0.1 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 FAA_hydrolase PF01557.13 ETS63001.1 - 3.8e-55 186.6 0.0 4.8e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2470 PF10615.4 ETS63002.1 - 5.2e-25 87.4 0.0 1e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 ETS63002.1 - 0.00015 21.6 0.2 0.00025 20.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) GSHPx PF00255.14 ETS63003.1 - 2.9e-40 135.9 1.5 3.8e-40 135.5 1.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 ETS63003.1 - 6.4e-07 29.0 0.3 4.3e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS63003.1 - 8.7e-07 28.5 0.1 1.4e-06 27.8 0.1 1.3 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 ETS63003.1 - 0.005 16.9 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) PA PF02225.17 ETS63003.1 - 0.048 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 PA domain Thioredoxin_2 PF13098.1 ETS63003.1 - 0.12 12.6 0.1 0.3 11.2 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain HTH_3 PF01381.17 ETS63004.1 - 0.67 9.8 2.8 5.4 6.9 0.0 3.3 4 0 0 4 4 4 0 Helix-turn-helix S-methyl_trans PF02574.11 ETS63006.1 - 3.6e-23 82.3 2.7 1.6e-19 70.3 0.0 3.8 3 2 0 3 3 3 2 Homocysteine S-methyltransferase Polysacc_deac_1 PF01522.16 ETS63008.1 - 1.2e-21 76.6 0.0 2.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 ETS63008.1 - 0.037 12.9 0.0 0.13 11.1 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 Erg28 PF03694.8 ETS63009.1 - 2.9e-37 127.0 0.8 3.6e-37 126.7 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein DNA_ligase_OB_2 PF14743.1 ETS63010.1 - 1.1e-23 82.6 0.1 2.8e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 ETS63010.1 - 1.6e-12 47.2 0.0 1.8e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain PIH1 PF08190.7 ETS63010.1 - 0.39 10.1 4.2 0.61 9.4 2.9 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Aldo_ket_red PF00248.16 ETS63012.1 - 4.8e-64 215.9 0.0 5.5e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family A_deaminase PF00962.17 ETS63013.1 - 1.3e-48 165.6 0.0 2e-48 165.0 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 ETS63013.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Mg_trans_NIPA PF05653.9 ETS63014.1 - 1.4e-91 306.6 23.7 1.9e-91 306.1 16.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 ETS63014.1 - 1.6e-06 28.1 7.1 1.6e-06 28.1 4.9 3.3 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 ETS63014.1 - 5.2e-06 26.6 6.0 5.2e-06 26.6 4.2 3.3 2 1 0 3 3 3 1 Multidrug resistance efflux transporter WSN PF02206.13 ETS63014.1 - 0.0018 18.0 0.3 0.0037 16.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function Mito_carr PF00153.22 ETS63015.1 - 3.5e-54 180.5 4.7 2.5e-19 68.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein START PF01852.14 ETS63016.1 - 4.7e-09 35.8 0.3 8e-09 35.1 0.2 1.3 1 0 0 1 1 1 1 START domain MoaE PF02391.12 ETS63017.1 - 1.5e-26 92.4 0.0 3.4e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 MoaE protein Ribonuclease PF00545.15 ETS63017.1 - 3.5e-16 59.0 2.0 6e-16 58.2 1.4 1.3 1 0 0 1 1 1 1 ribonuclease ACP_syn_III PF08545.5 ETS63017.1 - 0.091 12.4 0.4 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Frag1 PF10277.4 ETS63018.1 - 4.5e-36 124.3 19.6 5.4e-36 124.0 13.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Shisa PF13908.1 ETS63018.1 - 0.35 11.0 2.6 0.45 10.6 0.7 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4131 PF13567.1 ETS63018.1 - 5 6.5 15.0 7.4 5.9 0.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) 2TM PF13239.1 ETS63018.1 - 5.6 7.0 10.5 0.4 10.7 1.7 2.7 3 0 0 3 3 3 0 2TM domain Aminotran_1_2 PF00155.16 ETS63019.1 - 2.4e-16 59.6 0.0 3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS63019.1 - 9.3e-08 31.0 0.0 2.8e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase NCA2 PF08637.5 ETS63020.1 - 6.8e-94 314.0 0.1 5.8e-93 310.9 0.0 2.1 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Thioredoxin PF00085.15 ETS63021.1 - 1.1e-61 205.0 0.1 4.5e-31 106.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 ETS63021.1 - 5.1e-25 87.9 2.5 9.7e-25 87.0 0.4 2.5 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 ETS63021.1 - 1.4e-14 54.2 3.0 7.1e-08 32.6 0.0 3.5 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS63021.1 - 1.9e-11 43.9 0.3 0.0002 21.4 0.0 3.8 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 ETS63021.1 - 9.3e-11 41.6 0.7 8.7e-07 28.8 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 ETS63021.1 - 9e-09 35.0 0.2 0.0022 17.6 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.1 ETS63021.1 - 1.6e-05 24.4 0.0 0.24 10.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 ETS63021.1 - 9.1e-05 22.0 0.1 0.51 9.8 0.0 2.5 2 0 0 2 2 2 2 Redoxin HyaE PF07449.6 ETS63021.1 - 0.00013 21.8 0.0 0.0055 16.5 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 ETS63021.1 - 0.00047 19.9 0.0 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.1 ETS63021.1 - 0.0029 17.1 0.5 0.28 10.6 0.0 2.7 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 ETS63021.1 - 0.051 13.5 7.6 0.19 11.6 0.0 3.7 3 1 1 4 4 4 0 Thioredoxin TetR_C_5 PF08360.6 ETS63021.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Glutaredoxin PF00462.19 ETS63021.1 - 0.071 13.1 2.6 6.9 6.7 0.1 3.3 2 2 0 2 2 2 0 Glutaredoxin Propeptide_C1 PF08127.8 ETS63021.1 - 0.13 11.9 0.1 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C1 propeptide XPG_I_2 PF12813.2 ETS63022.1 - 1.2e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 ETS63022.1 - 5e-05 23.4 0.0 0.0079 16.4 0.0 2.5 2 0 0 2 2 2 2 XPG N-terminal domain SPT6_acidic PF14632.1 ETS63022.1 - 0.3 11.2 5.5 0.61 10.2 3.8 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Lactamase_B PF00753.22 ETS63023.1 - 3.6e-19 69.1 0.7 1.1e-18 67.6 0.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS63023.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Evr1_Alr PF04777.8 ETS63024.1 - 3.1e-28 97.4 0.1 5.3e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Glyco_hydro_cc PF11790.3 ETS63025.1 - 1.6e-45 155.4 0.1 2.1e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MIP-T3 PF10243.4 ETS63025.1 - 0.039 12.4 2.5 0.047 12.1 1.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Neur_chan_memb PF02932.11 ETS63025.1 - 0.18 11.6 2.1 0.32 10.8 1.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 ETS63025.1 - 0.76 7.9 35.5 1.1 7.5 24.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 ETS63025.1 - 1.7 6.7 10.4 2.5 6.1 7.2 1.2 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 ETS63025.1 - 2.1 5.9 8.7 2.6 5.6 6.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 ETS63025.1 - 7.5 5.6 9.4 11 5.0 6.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CIA30 PF08547.7 ETS63026.1 - 1.1e-20 74.0 0.0 1.3e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Aldose_epim PF01263.15 ETS63026.1 - 3e-10 39.7 0.0 2.8e-08 33.2 0.0 2.7 1 1 0 1 1 1 1 Aldose 1-epimerase His_Phos_2 PF00328.17 ETS63027.1 - 5.5e-15 55.5 0.0 1.4e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Acatn PF13000.2 ETS63028.1 - 2e-139 465.6 31.6 1.1e-68 232.1 10.5 4.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_Mycoplasma PF07672.8 ETS63028.1 - 0.00065 18.9 9.3 0.00065 18.9 6.4 2.1 2 1 0 2 2 2 1 Mycoplasma MFS transporter Peptidase_M48 PF01435.13 ETS63029.1 - 3.4e-32 111.8 0.0 6.3e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 HTH_1 PF00126.22 ETS63029.1 - 0.061 13.0 0.5 17 5.2 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family adh_short PF00106.20 ETS63030.1 - 2.1e-16 60.2 0.8 9.7e-15 54.8 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS63030.1 - 1.1e-05 25.2 0.1 2.1e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 KR domain FtsJ PF01728.14 ETS63031.1 - 3.7e-60 202.9 0.0 4.7e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase rRNA_processing PF08524.6 ETS63032.1 - 1.6e-09 37.7 7.9 4.5e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 rRNA processing Methyltransf_PK PF05891.7 ETS63033.1 - 3.8e-61 206.1 0.0 3e-34 118.2 0.0 3.0 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 ETS63033.1 - 4.1e-09 36.3 0.0 6.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS63033.1 - 9.1e-06 26.0 0.0 0.0068 16.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 ETS63033.1 - 8.8e-05 22.8 0.0 0.44 10.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63033.1 - 0.00035 21.1 0.0 0.00078 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS63033.1 - 0.0011 19.3 0.0 0.025 15.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 ETS63033.1 - 0.021 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF295 PF03478.13 ETS63033.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF295) DUF1399 PF07173.7 ETS63034.1 - 1.8e-17 63.8 0.3 3.1e-14 53.4 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF1399) Glyco_transf_15 PF01793.11 ETS63036.1 - 1e-126 422.4 3.0 1.2e-126 422.1 2.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase adh_short PF00106.20 ETS63037.1 - 1.4e-31 109.6 4.4 4.4e-22 78.7 0.9 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETS63037.1 - 3.3e-23 82.7 4.7 2.2e-21 76.7 3.3 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS63037.1 - 2.6e-12 46.7 4.4 1.6e-08 34.4 0.5 2.2 1 1 1 2 2 2 2 KR domain Epimerase PF01370.16 ETS63037.1 - 0.00028 20.3 0.2 0.00038 19.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 ETS63037.1 - 0.0044 16.6 1.0 0.0072 15.9 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.19 ETS63038.1 - 2.9e-41 141.3 0.1 3.6e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Cytadhesin_P30 PF07271.6 ETS63038.1 - 0.14 11.3 0.3 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Cytadhesin P30/P32 Abhydrolase_6 PF12697.2 ETS63039.1 - 1.2e-28 100.5 0.0 1.8e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63039.1 - 1.6e-14 53.8 0.0 2.8e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63039.1 - 8.4e-14 51.6 0.3 6.7e-13 48.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 ETS63039.1 - 9e-10 38.5 0.0 1.9e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 ETS63039.1 - 1.1e-06 29.0 0.0 1.3e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 ETS63039.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 ETS63039.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 ETS63039.1 - 0.082 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 ETS63039.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LRV PF01816.12 ETS63039.1 - 0.1 12.7 0.1 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat variant Chlorophyllase PF07224.6 ETS63039.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2048 PF09752.4 ETS63039.1 - 0.15 10.9 0.1 11 4.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Transp_Tc5_C PF04236.10 ETS63040.1 - 0.062 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Torsin PF06309.6 ETS63041.1 - 2.6e-05 24.1 0.0 0.00025 20.9 0.0 2.4 3 0 0 3 3 3 1 Torsin Zeta_toxin PF06414.7 ETS63041.1 - 3.5e-05 22.9 0.0 6.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 ETS63041.1 - 3.8e-05 24.4 0.0 7.1e-05 23.6 0.0 1.8 2 1 0 2 2 1 1 AAA domain MobB PF03205.9 ETS63041.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETS63041.1 - 0.00024 20.9 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 ETS63041.1 - 0.00036 20.0 0.1 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 ETS63041.1 - 0.00056 19.9 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 ETS63041.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.1 ETS63041.1 - 0.0022 17.6 0.1 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS63041.1 - 0.0027 17.3 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 ETS63041.1 - 0.0037 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase LpxK PF02606.9 ETS63041.1 - 0.0042 16.0 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase NTPase_1 PF03266.10 ETS63041.1 - 0.0045 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 NTPase PRK PF00485.13 ETS63041.1 - 0.0064 16.0 0.0 0.041 13.4 0.0 2.2 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 ETS63041.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 ETS63041.1 - 0.0096 15.8 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS63041.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain ArgK PF03308.11 ETS63041.1 - 0.01 14.6 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 ETS63041.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 ETS63041.1 - 0.018 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 ETS63041.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 ETS63041.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 ETS63041.1 - 0.036 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 ETS63041.1 - 0.039 13.3 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_25 PF13481.1 ETS63041.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 ETS63041.1 - 0.048 13.0 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 ETS63041.1 - 0.067 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 ETS63041.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 ETS63041.1 - 0.08 12.6 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) 6PF2K PF01591.13 ETS63041.1 - 0.083 11.9 0.0 0.33 9.9 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase SMC_N PF02463.14 ETS63041.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_11 PF13086.1 ETS63041.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 ETS63041.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF938 PF06080.7 ETS63042.1 - 4.6e-32 111.2 0.0 1.5e-31 109.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Nucleo_P87 PF07267.6 ETS63044.1 - 0.77 8.3 0.7 2.2 6.8 0.5 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 His_Phos_2 PF00328.17 ETS63045.1 - 7.1e-24 84.7 0.0 9.3e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SPC12 PF06645.8 ETS63046.1 - 1.3e-24 85.8 0.1 1.4e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Polysacc_synt_3 PF13440.1 ETS63046.1 - 0.034 13.6 0.4 0.035 13.5 0.3 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ETRAMP PF09716.5 ETS63046.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4564 PF15169.1 ETS63046.1 - 0.14 11.9 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Fungal_trans PF04082.13 ETS63047.1 - 1.8e-22 79.4 0.9 6.7e-22 77.6 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63047.1 - 7.3e-08 32.1 8.7 1.2e-07 31.4 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.7 ETS63049.1 - 3.3e-33 114.6 0.0 6.8e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS63049.1 - 3.3e-30 104.8 0.0 7.8e-30 103.5 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 ETS63049.1 - 4e-08 32.9 0.0 9.1e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS63049.1 - 8.8e-06 25.5 0.4 1.8e-05 24.4 0.3 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS63049.1 - 2.6e-05 24.2 3.2 3.2e-05 23.9 0.4 2.4 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 ETS63049.1 - 0.0019 16.9 0.0 0.0045 15.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 ETS63049.1 - 0.0055 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site HAD_2 PF13419.1 ETS63050.1 - 3.4e-11 43.6 1.1 2.8e-10 40.6 0.7 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS63050.1 - 7.8e-06 25.5 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 ETS63050.1 - 0.019 15.3 0.0 0.033 14.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-DHHC PF01529.15 ETS63053.1 - 9.5e-56 187.9 0.0 6.1e-55 185.2 0.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Hemagglutinin PF00509.13 ETS63053.1 - 0.057 11.5 0.0 0.088 10.9 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin DZR PF12773.2 ETS63053.1 - 0.064 13.0 5.2 0.23 11.2 3.6 1.9 1 0 0 1 1 1 0 Double zinc ribbon LIM PF00412.17 ETS63054.1 - 4.4e-21 74.6 16.4 1e-11 44.7 4.4 2.4 2 0 0 2 2 2 2 LIM domain Cytochrom_c3_2 PF14537.1 ETS63054.1 - 2.5 8.5 10.7 1.6 9.1 2.7 2.4 2 0 0 2 2 2 0 Cytochrome c3 PMSR PF01625.16 ETS63055.1 - 2.3e-55 186.7 2.2 3e-55 186.3 1.5 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Calc_CGRP_IAPP PF00214.14 ETS63055.1 - 0.15 12.0 0.2 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Exo70 PF03081.10 ETS63056.1 - 3.6e-82 276.1 0.0 2.1e-81 273.5 0.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 ETS63056.1 - 0.74 9.6 4.1 9 6.1 0.2 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SLT PF01464.15 ETS63057.1 - 0.00015 21.2 0.7 0.12 11.8 0.0 2.9 3 0 0 3 3 3 2 Transglycosylase SLT domain Macoilin PF09726.4 ETS63057.1 - 7.7 4.6 7.8 10 4.2 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Thiolase_N PF00108.18 ETS63058.1 - 4.5e-73 245.4 0.1 6.3e-73 244.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS63058.1 - 2.1e-42 143.4 0.1 3.9e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 ETS63058.1 - 0.01 15.3 2.1 0.013 15.0 0.4 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Nucleos_tra2_C PF07662.8 ETS63059.1 - 1.2e-63 214.3 8.0 1.2e-63 214.3 5.5 2.3 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 ETS63059.1 - 9.7e-08 32.2 6.3 9.7e-08 32.2 4.4 3.1 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 ETS63059.1 - 0.55 10.1 23.1 0.078 12.8 9.2 3.6 2 1 1 3 3 3 0 Nucleoside recognition DPM2 PF07297.7 ETS63060.1 - 2.1e-15 56.7 0.1 2.4e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 ETS63060.1 - 3e-07 30.1 0.1 3.2e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 PIG-P DUF1469 PF07332.6 ETS63060.1 - 0.028 14.1 2.8 0.036 13.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4131 PF13567.1 ETS63060.1 - 0.14 11.5 1.4 0.15 11.4 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1648 PF07853.6 ETS63060.1 - 0.2 11.1 2.3 0.46 10.0 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Peptidase_S24 PF00717.18 ETS63062.1 - 4.3e-06 26.2 0.1 0.00029 20.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.4 ETS63062.1 - 0.0036 16.8 0.0 0.048 13.1 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 DUF3425 PF11905.3 ETS63063.1 - 1.6e-12 47.4 1.0 9.1e-11 41.7 0.7 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS63063.1 - 3.4e-09 36.5 8.6 1.9e-08 34.1 6.2 2.1 1 1 0 1 1 1 1 bZIP transcription factor BNIP2 PF12496.3 ETS63063.1 - 3.2 7.9 10.5 0.55 10.3 2.1 2.5 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Tmemb_cc2 PF10267.4 ETS63063.1 - 9.6 4.6 9.9 0.1 11.1 0.6 1.9 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein VHS PF00790.14 ETS63064.1 - 1e-26 93.2 0.0 2.4e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 ETS63064.1 - 1.8e-06 27.8 4.6 6.1e-06 26.1 1.4 2.5 2 0 0 2 2 2 1 GAT domain SAPS PF04499.10 ETS63065.1 - 8.7 4.8 5.9 12 4.3 4.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Carn_acyltransf PF00755.15 ETS63066.1 - 3.7e-167 557.0 0.0 4.6e-167 556.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glyco_hydro_3_C PF01915.17 ETS63067.1 - 0.031 13.8 0.0 0.99 8.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain DUF1505 PF07403.6 ETS63067.1 - 0.11 12.4 0.2 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) Ofd1_CTDD PF10637.4 ETS63069.1 - 5.4e-98 327.3 0.0 1.1e-92 309.9 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 ETS63069.1 - 5.4e-19 68.5 0.3 3.4e-17 62.7 0.0 2.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-CHY PF05495.7 ETS63069.1 - 9.8e-14 51.2 12.7 1.6e-13 50.5 8.8 1.3 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.9 ETS63069.1 - 0.011 15.4 1.1 0.027 14.1 0.8 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS 2OG-FeII_Oxy_4 PF13661.1 ETS63069.1 - 0.034 13.7 0.0 0.52 9.9 0.0 2.6 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily zinc_ribbon_2 PF13240.1 ETS63069.1 - 0.036 13.5 3.6 0.86 9.1 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 ETS63069.1 - 1.9 7.8 6.6 22 4.3 4.6 2.3 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 ETS63069.1 - 3.7 7.4 9.1 8.8 6.2 6.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 ETS63069.1 - 8.3 6.4 10.7 4.9 7.1 2.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain SCP2 PF02036.12 ETS63070.1 - 2.4e-16 59.8 0.0 4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 ETS63070.1 - 0.0044 16.9 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal GPI-anchored PF10342.4 ETS63071.1 - 1.3e-09 38.4 0.0 1.3e-09 38.4 0.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.27 ETS63071.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat Med3 PF11593.3 ETS63071.1 - 7.8 5.6 14.0 11 5.1 9.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Abhydrolase_1 PF00561.15 ETS63072.1 - 1.1e-18 67.6 0.2 5e-18 65.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS63072.1 - 2.7e-17 63.4 0.6 4.2e-17 62.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63072.1 - 2.6e-07 30.4 0.0 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 ETS63072.1 - 0.0023 17.2 0.1 0.0086 15.3 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 ETS63072.1 - 0.0039 16.4 0.0 0.032 13.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 ETS63072.1 - 0.12 12.0 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal EHN PF06441.7 ETS63073.1 - 4.3e-32 110.3 0.2 7.3e-32 109.6 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETS63073.1 - 3.3e-08 33.7 1.0 4e-08 33.4 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63073.1 - 1.7e-05 24.4 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PhzC-PhzF PF02567.11 ETS63074.1 - 6.8e-47 160.0 0.0 8.2e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein PhoD PF09423.5 ETS63075.1 - 1.2e-125 419.6 9.6 2.8e-125 418.4 6.6 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 ETS63075.1 - 0.023 14.5 0.0 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Phytase-like PF13449.1 ETS63076.1 - 1e-18 67.7 0.1 3.2e-18 66.1 0.0 1.9 2 1 0 2 2 2 1 Esterase-like activity of phytase Mito_carr PF00153.22 ETS63077.1 - 1.3e-34 117.7 16.0 7.1e-15 54.4 0.3 5.1 4 2 0 4 4 4 4 Mitochondrial carrier protein Otopetrin PF03189.8 ETS63077.1 - 0.23 10.4 0.3 0.31 10.0 0.1 1.4 2 0 0 2 2 2 0 Otopetrin Dicty_REP PF05086.7 ETS63077.1 - 2.1 6.0 6.0 2.7 5.6 4.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GIY-YIG PF01541.19 ETS63078.1 - 0.00079 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Arginase PF00491.16 ETS63079.1 - 6e-82 275.0 0.1 8.7e-82 274.5 0.1 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 ETS63079.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain FGGY_C PF02782.11 ETS63080.1 - 8.4e-46 156.0 0.1 1.5e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 ETS63080.1 - 4.6e-20 71.9 1.3 6.7e-18 64.8 0.9 3.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 ETS63080.1 - 2.4e-07 30.3 1.3 6e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family PTH2 PF01981.11 ETS63081.1 - 1.7e-38 130.8 0.7 1.9e-26 92.0 0.2 2.1 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 ADH_N PF08240.7 ETS63082.1 - 5.4e-23 80.8 8.8 5.4e-23 80.8 6.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS63082.1 - 1.8e-16 59.8 0.0 3.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63082.1 - 2.3e-05 25.2 0.0 4.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS63082.1 - 0.00012 21.3 0.1 0.00087 18.4 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 ETS63082.1 - 0.0088 14.7 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NADH_4Fe-4S PF10589.4 ETS63082.1 - 0.16 11.1 1.8 0.37 9.9 1.3 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region MSSP PF03940.8 ETS63082.1 - 3.1 7.2 10.2 1.6 8.2 2.2 2.6 2 0 0 2 2 2 0 Male specific sperm protein SBF PF01758.11 ETS63083.1 - 1.1e-45 155.3 12.9 1.1e-45 155.3 8.9 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family p450 PF00067.17 ETS63084.1 - 1.3e-54 185.4 0.0 3.2e-35 121.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DRMBL PF07522.9 ETS63085.1 - 3e-26 91.6 0.0 5.7e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 ETS63085.1 - 1.7e-07 30.9 0.0 3.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-Di19 PF05605.7 ETS63085.1 - 0.16 12.1 2.1 5.9 7.1 0.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PI-PLC-X PF00388.14 ETS63086.1 - 6.7e-47 158.5 0.0 1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 ETS63086.1 - 1.5e-32 112.0 0.0 2.3e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 ETS63086.1 - 4.5e-05 23.2 0.6 0.0018 18.1 0.1 3.3 3 1 0 3 3 3 1 C2 domain Peptidase_M50B PF13398.1 ETS63087.1 - 0.034 13.5 3.5 0.046 13.1 2.5 1.1 1 0 0 1 1 1 0 Peptidase M50B-like SET PF00856.23 ETS63088.1 - 9.4e-07 29.2 0.0 1.7e-05 25.2 0.0 2.7 1 1 0 1 1 1 1 SET domain Sugar_tr PF00083.19 ETS63089.1 - 1e-31 110.0 24.8 2e-16 59.5 1.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS63089.1 - 1.3e-18 66.8 50.3 3.2e-12 45.8 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_5 PF12695.2 ETS63090.1 - 1.2e-06 28.3 0.4 3.3e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS63090.1 - 2e-06 27.2 0.1 4.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS63090.1 - 0.0048 16.4 0.1 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tannase PF07519.6 ETS63090.1 - 0.039 12.6 0.2 0.09 11.4 0.1 1.5 1 1 0 1 1 1 0 Tannase and feruloyl esterase GMC_oxred_N PF00732.14 ETS63091.1 - 2.5e-75 253.4 0.0 3.1e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS63091.1 - 7.2e-38 130.1 0.1 1.3e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS63091.1 - 0.0019 17.1 0.5 0.0057 15.6 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS63091.1 - 0.0046 16.9 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS63091.1 - 0.0058 15.5 0.0 0.0088 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS63091.1 - 0.07 11.9 0.1 0.07 11.9 0.1 2.4 3 0 0 3 3 3 0 FAD binding domain UPF0075 PF03702.9 ETS63091.1 - 0.13 11.1 0.0 0.83 8.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) Lactamase_B_2 PF12706.2 ETS63092.1 - 1.9e-29 102.6 0.0 4.4e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_31 PF13847.1 ETS63092.1 - 6.6e-15 55.0 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63092.1 - 8.1e-13 48.9 0.0 3.1e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS63092.1 - 6.5e-07 29.7 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Lactamase_B_3 PF13483.1 ETS63092.1 - 3.3e-06 26.9 0.1 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_26 PF13659.1 ETS63092.1 - 3.7e-06 26.9 0.0 1.1e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS63092.1 - 7.7e-05 22.3 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS63092.1 - 0.00095 19.4 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS63092.1 - 0.022 15.2 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS63092.1 - 0.053 12.8 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.1 ETS63092.1 - 0.11 12.1 0.0 0.42 10.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain UPF0052 PF01933.13 ETS63093.1 - 2.3e-40 138.7 0.0 1.8e-27 96.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 AAA_9 PF12781.2 ETS63093.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 ATP-binding dynein motor region D5 GalP_UDP_transf PF01087.17 ETS63094.1 - 3.4e-68 229.3 0.9 5.5e-68 228.6 0.6 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 ETS63094.1 - 1.5e-45 154.7 0.0 2.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 ETS63094.1 - 0.0026 18.2 0.1 0.0071 16.8 0.0 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETS63094.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding BAF1_ABF1 PF04684.8 ETS63094.1 - 4.8 5.9 9.5 7.6 5.2 6.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2781 PF10914.3 ETS63095.1 - 1.1e-35 122.6 6.0 1.2e-35 122.4 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Zn_clus PF00172.13 ETS63096.1 - 1.4e-06 28.0 11.3 2.9e-06 27.0 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 ETS63098.1 - 4.2e-11 43.2 0.0 7.2e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1682 PF07946.9 ETS63099.1 - 3e-79 266.1 0.0 3.4e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) adh_short PF00106.20 ETS63100.1 - 6.8e-18 65.1 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS63100.1 - 1.9e-08 34.2 0.1 3.9e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS63100.1 - 1.1e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS63100.1 - 0.00056 19.4 0.0 0.00093 18.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS63100.1 - 0.001 19.1 0.1 0.0019 18.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF4302 PF14135.1 ETS63100.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Pmp3 PF01679.12 ETS63101.1 - 5.4e-12 45.2 6.6 7.9e-12 44.6 4.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Thioredoxin_4 PF13462.1 ETS63102.1 - 2.7e-05 24.2 0.0 0.0012 18.8 0.0 2.3 2 1 0 2 2 2 2 Thioredoxin DSBA PF01323.15 ETS63102.1 - 0.024 14.1 0.2 0.71 9.4 0.0 2.4 2 0 0 2 2 2 0 DSBA-like thioredoxin domain MFS_1 PF07690.11 ETS63103.1 - 2.1e-42 145.1 47.3 4e-41 140.8 30.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS63103.1 - 7e-16 57.8 12.2 7e-16 57.8 8.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 ETS63103.1 - 6.2e-13 47.8 11.8 6.2e-13 47.8 8.2 2.5 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) ADH_zinc_N PF00107.21 ETS63104.1 - 3.2e-18 65.5 0.7 5.6e-18 64.7 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63104.1 - 1.6e-17 64.6 1.3 5.7e-16 59.5 0.3 2.7 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS63104.1 - 2.3e-12 46.6 0.0 5.7e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PHBC_N PF12551.3 ETS63104.1 - 0.039 13.4 0.1 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal ELFV_dehydrog PF00208.16 ETS63104.1 - 0.043 13.3 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short_C2 PF13561.1 ETS63104.1 - 0.052 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Peptidase_S10 PF00450.17 ETS63106.1 - 1.8e-115 386.4 0.6 2.4e-115 386.0 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS63106.1 - 0.0016 18.4 0.0 0.0098 15.7 0.0 2.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 ETS63109.1 - 4.2e-86 289.7 0.2 5.7e-86 289.2 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.19 ETS63110.1 - 1.9e-78 264.0 12.9 2.6e-78 263.6 8.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS63110.1 - 4.9e-19 68.2 22.6 3.5e-12 45.7 5.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GTP_EFTU PF00009.22 ETS63111.1 - 1.5e-46 158.2 0.0 2.2e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 ETS63111.1 - 7.1e-34 115.9 0.5 1.2e-33 115.2 0.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 ETS63111.1 - 8.6e-18 63.9 0.0 1.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS63111.1 - 1.2e-06 28.5 0.1 2.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS63111.1 - 0.00025 21.0 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 ETS63111.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 Elongation Factor G, domain II ICL PF00463.16 ETS63112.1 - 1.4e-186 620.7 0.1 1.7e-186 620.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 ETS63112.1 - 8.9e-11 41.4 0.1 5.6e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.4 ETS63112.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) JHBP PF06585.6 ETS63112.1 - 0.26 10.0 0.1 7.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) Methyltransf_16 PF10294.4 ETS63113.1 - 8.2e-15 54.6 0.0 1.6e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETS63113.1 - 3.9e-05 24.1 0.0 8.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS63113.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETS63113.1 - 0.045 13.7 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 ETS63113.1 - 0.068 13.2 0.2 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_12 PF08242.7 ETS63113.1 - 0.087 13.3 0.1 0.68 10.4 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Pet191_N PF10203.4 ETS63116.1 - 1.7e-20 72.7 1.6 2.8e-20 72.1 1.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Abhydrolase_5 PF12695.2 ETS63116.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_16 PF00722.16 ETS63117.1 - 6.5e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 ETS63118.1 - 3.8e-32 111.3 38.5 3.8e-32 111.3 26.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS63118.1 - 8.2e-06 24.2 1.0 1.3e-05 23.6 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acyl_transf_3 PF01757.17 ETS63119.1 - 2e-12 46.6 41.6 3.7e-12 45.7 27.6 2.1 2 0 0 2 2 2 1 Acyltransferase family CoA_binding PF02629.14 ETS63120.1 - 1.6e-19 70.2 1.2 2.7e-19 69.4 0.8 1.3 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 ETS63120.1 - 1e-11 44.6 0.0 2.5e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase GFO_IDH_MocA PF01408.17 ETS63120.1 - 0.0003 21.2 0.1 0.00059 20.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Succ_CoA_lig PF13607.1 ETS63120.1 - 0.0008 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 ETS63120.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 2 0 0 2 2 2 0 CoA binding domain Ligase_CoA PF00549.14 ETS63121.1 - 2.3e-10 40.2 0.5 4e-10 39.4 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Peptidase_C12 PF01088.16 ETS63122.1 - 1.4e-58 197.6 0.0 1.6e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med10 PF09748.4 ETS63123.1 - 3.8e-20 72.0 0.0 6e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2236 PF09995.4 ETS63124.1 - 3e-13 49.6 0.2 6.2e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CBFD_NFYB_HMF PF00808.18 ETS63125.1 - 9.5e-19 67.2 0.8 1.5e-18 66.6 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS63125.1 - 2.1e-09 37.3 1.9 2.3e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 tRNA-synt_2 PF00152.15 ETS63126.1 - 5.2e-74 249.0 0.0 1.1e-73 247.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 ETS63126.1 - 5.1e-16 58.3 0.1 7e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 ETS63126.1 - 4e-07 29.7 0.1 1.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 ETS63126.1 - 0.0058 15.8 0.3 0.41 9.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) His_Phos_1 PF00300.17 ETS63127.1 - 1.1e-16 61.2 0.1 1.6e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_zinc_N PF00107.21 ETS63128.1 - 3.1e-25 88.2 0.0 7.7e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63128.1 - 4.2e-08 34.1 0.0 8.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AFOR_C PF01314.13 ETS63128.1 - 0.00024 19.9 0.2 0.00032 19.4 0.1 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 ELFV_dehydrog PF00208.16 ETS63128.1 - 0.024 14.2 0.5 0.036 13.6 0.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 ETS63128.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF4384 PF14326.1 ETS63128.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) DUF500 PF04366.7 ETS63129.1 - 5.8e-31 106.5 0.0 1.4e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) HAD PF12710.2 ETS63129.1 - 6.9e-07 29.6 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIRA_B PF09453.5 ETS63129.1 - 0.49 10.0 2.2 0.84 9.2 0.5 2.1 2 0 0 2 2 2 0 HIRA B motif Phasin PF05597.6 ETS63131.1 - 0.0092 15.7 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) ECH PF00378.15 ETS63132.1 - 2.3e-38 131.7 0.1 3.3e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pterin_4a PF01329.14 ETS63132.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase PWI PF01480.12 ETS63133.1 - 4.3e-30 103.6 0.0 6.1e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 PWI domain Methyltransf_18 PF12847.2 ETS63134.1 - 0.03 14.9 2.1 0.051 14.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain PRP1_N PF06424.7 ETS63135.1 - 0.046 14.0 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF473 PF04322.7 ETS63135.1 - 0.058 13.0 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF473) dCMP_cyt_deam_1 PF00383.17 ETS63136.1 - 5.5e-15 54.8 0.0 1.1e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 ETS63136.1 - 2.3e-11 43.7 0.5 1.1e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 ETS63136.1 - 0.0021 17.5 1.2 0.026 13.9 0.0 2.3 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases MFS_1 PF07690.11 ETS63137.1 - 1.1e-19 70.4 25.1 3.6e-14 52.2 8.7 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF427 PF04248.7 ETS63137.1 - 1.7e-15 56.4 0.0 3.4e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF427) ATG22 PF11700.3 ETS63137.1 - 7.3e-08 31.3 7.9 7.3e-08 31.3 5.4 2.7 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like Penaeidin PF05927.6 ETS63138.1 - 0.042 14.3 0.6 0.13 12.8 0.4 1.8 1 1 0 1 1 1 0 Penaeidin FGGY_C PF02782.11 ETS63139.1 - 1.1e-15 57.7 0.0 2.5e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 ETS63139.1 - 1.1e-10 41.2 0.0 8.7e-06 25.2 0.0 3.6 2 1 1 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain NMO PF03060.10 ETS63140.1 - 5.6e-53 180.2 2.8 1.1e-52 179.2 1.9 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase CoA_transf_3 PF02515.12 ETS63141.1 - 7.1e-64 214.5 0.3 7.1e-64 214.5 0.2 1.5 2 0 0 2 2 2 1 CoA-transferase family III Got1 PF04178.7 ETS63142.1 - 3.5e-19 69.0 25.8 4.5e-19 68.6 17.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Zn_clus PF00172.13 ETS63143.1 - 0.00014 21.6 10.3 0.00028 20.7 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 ETS63143.1 - 0.0039 16.9 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 ETS63143.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 PAS domain Allantoicase PF03561.10 ETS63144.1 - 2.3e-81 270.6 0.0 8.2e-41 138.9 0.0 3.1 2 1 0 2 2 2 2 Allantoicase repeat PAF-AH_p_II PF03403.8 ETS63144.1 - 2.8e-48 164.1 0.0 1.9e-44 151.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Ureidogly_hydro PF04115.7 ETS63144.1 - 2.4e-45 153.8 0.0 3.9e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Abhydrolase_5 PF12695.2 ETS63144.1 - 1.3e-10 41.1 0.1 7.1e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS63144.1 - 6.2e-09 36.0 1.9 8e-09 35.7 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family HAD_2 PF13419.1 ETS63144.1 - 1.1e-08 35.4 0.0 1.5e-07 31.8 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Esterase PF00756.15 ETS63144.1 - 0.023 14.1 0.2 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Hydrolase_4 PF12146.3 ETS63144.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase2 PF12740.2 ETS63144.1 - 0.14 10.9 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme PRT_C PF08372.5 ETS63145.1 - 0.3 10.5 1.5 3.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal SNARE PF05739.14 ETS63147.1 - 2.1e-12 46.5 1.5 3.5e-12 45.8 1.0 1.4 1 0 0 1 1 1 1 SNARE domain DNA_pol_B PF00136.16 ETS63148.1 - 8.4e-93 311.6 0.0 1.2e-92 311.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 ETS63148.1 - 7.4e-21 74.3 0.0 8.5e-11 41.2 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 ETS63148.1 - 3.1e-10 39.8 9.1 6.3e-10 38.9 6.3 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta PSP94 PF05825.6 ETS63148.1 - 4.2 7.7 8.1 3.7 7.8 1.3 2.4 1 1 1 2 2 2 0 Beta-microseminoprotein (PSP-94) MutL_C PF08676.6 ETS63149.1 - 3e-21 75.5 0.0 9e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 ETS63149.1 - 6.4e-20 70.7 0.0 1.4e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 ETS63149.1 - 5.2e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETS63149.1 - 3.3e-10 39.6 0.0 8.6e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3585 PF12130.3 ETS63150.1 - 0.00071 19.4 3.2 0.0013 18.5 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3585) APG6 PF04111.7 ETS63150.1 - 0.031 13.3 0.6 0.037 13.0 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ScpA_ScpB PF02616.9 ETS63150.1 - 0.047 13.2 0.4 0.056 13.0 0.3 1.1 1 0 0 1 1 1 0 ScpA/B protein DASH_Dad2 PF08654.5 ETS63150.1 - 0.13 12.2 0.8 0.27 11.2 0.2 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 Atg14 PF10186.4 ETS63150.1 - 0.15 10.9 1.0 0.2 10.5 0.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ERG2_Sigma1R PF04622.7 ETS63151.1 - 8.6e-97 322.6 0.0 9.9e-97 322.4 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Rhodanese PF00581.15 ETS63152.1 - 1.8e-08 34.7 0.0 4.2e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain KduI PF04962.7 ETS63152.1 - 0.012 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family ECH PF00378.15 ETS63153.1 - 4.2e-53 179.9 0.0 5.3e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ACC_epsilon PF13822.1 ETS63154.1 - 0.87 9.9 7.1 0.7 10.2 2.5 2.2 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit AMP-binding PF00501.23 ETS63155.1 - 1.8e-78 263.7 0.4 1.5e-51 175.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 ETS63155.1 - 6.4e-09 36.6 0.0 3.5e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.23 ETS63156.1 - 1.4e-08 34.3 2.9 3.8e-08 32.9 2.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS63156.1 - 0.00011 22.1 0.0 0.00066 19.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EHN PF06441.7 ETS63157.1 - 3.5e-32 110.6 0.1 6.3e-32 109.8 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETS63157.1 - 6.9e-08 32.6 0.1 4.9e-07 29.8 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63157.1 - 0.00024 20.7 0.0 0.0033 17.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_L37 PF08561.5 ETS63158.1 - 8.2e-29 99.0 5.4 3.1e-27 93.9 3.7 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 NARP1 PF12569.3 ETS63158.1 - 0.14 10.9 8.5 0.17 10.5 5.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3275 PF11679.3 ETS63158.1 - 9.3 5.8 13.8 0.24 11.0 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) CUE PF02845.11 ETS63159.1 - 3.1e-11 42.5 0.0 6.3e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 CUE domain Abhydrolase_6 PF12697.2 ETS63160.1 - 8e-16 58.6 0.7 1.5e-15 57.7 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63160.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M19 PF01244.16 ETS63161.1 - 3.1e-86 289.2 0.0 3.8e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Glyco_hydro_31 PF01055.21 ETS63162.1 - 2.1e-80 270.7 0.0 7.7e-80 268.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS63162.1 - 2.5e-08 33.6 0.0 7.6e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 ETS63163.1 - 1.8e-35 122.2 21.0 2.4e-35 121.9 14.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 ETS63164.1 - 1e-86 291.1 6.5 1.5e-86 290.5 4.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 ETS63164.1 - 8.7e-07 29.2 0.1 2.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PXA PF02194.10 ETS63165.1 - 7.3e-18 64.7 0.0 1e-16 61.0 0.0 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 ETS63165.1 - 0.0026 17.8 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal peroxidase PF00141.18 ETS63166.1 - 4e-50 170.4 0.0 5.8e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Glyco_hydro_88 PF07470.8 ETS63169.1 - 4.1e-67 226.6 0.9 5.4e-67 226.2 0.4 1.3 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Acetyltransf_3 PF13302.1 ETS63170.1 - 6.1e-13 49.1 0.0 1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS63170.1 - 6e-05 23.0 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 ETS63170.1 - 0.017 15.0 0.0 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UvdE PF03851.9 ETS63171.1 - 9.2e-86 287.2 0.0 1.3e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE RCC1 PF00415.13 ETS63172.1 - 5e-25 87.4 17.0 7.4e-11 42.0 0.0 8.4 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS63172.1 - 2.9e-14 52.2 11.8 9e-09 34.7 0.3 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat NHL PF01436.16 ETS63172.1 - 0.27 11.2 1.6 2.5 8.2 0.4 2.6 2 0 0 2 2 2 0 NHL repeat 4HBT PF03061.17 ETS63174.1 - 3e-10 40.0 0.0 5.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily N6-adenineMlase PF10237.4 ETS63175.1 - 2.4e-31 108.5 0.0 4.6e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 ETS63175.1 - 0.093 12.7 0.2 0.2 11.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain PRELI PF04707.9 ETS63176.1 - 1.1e-40 138.7 0.0 1.4e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Glyco_hydro_47 PF01532.15 ETS63177.1 - 5.2e-125 417.6 0.0 6.3e-125 417.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 ETS63177.1 - 0.00044 19.7 0.6 0.16 11.2 0.0 3.0 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 TMEM154 PF15102.1 ETS63178.1 - 0.72 9.5 3.9 0.44 10.2 0.3 2.2 2 1 0 2 2 2 0 TMEM154 protein family WES_acyltransf PF03007.11 ETS63179.1 - 4.6e-14 52.5 1.7 2.9e-13 49.9 0.0 2.5 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 ETS63179.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Mrr_cat_2 PF13156.1 ETS63179.1 - 0.031 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease Fungal_trans_2 PF11951.3 ETS63180.1 - 2.4e-12 46.1 1.4 1.6e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63180.1 - 5.7e-09 35.7 12.5 9.6e-09 35.0 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GalKase_gal_bdg PF10509.4 ETS63181.1 - 3.5e-21 74.2 0.0 7.2e-21 73.2 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 ETS63181.1 - 6.2e-12 45.4 0.2 1.7e-11 43.9 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS63181.1 - 1.1e-11 44.7 0.1 6.5e-10 39.0 0.0 2.6 2 0 0 2 2 2 1 GHMP kinases C terminal Fungal_trans PF04082.13 ETS63182.1 - 4.8e-06 25.6 0.1 8.4e-06 24.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63182.1 - 1.7e-05 24.5 11.1 3.3e-05 23.7 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS63183.1 - 3.8e-35 121.2 52.9 1.2e-34 119.5 36.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS63183.1 - 2.2e-10 39.6 14.9 2.2e-10 39.6 10.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter PsbT PF01405.12 ETS63183.1 - 0.057 13.0 0.3 0.25 10.9 0.2 2.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein FPN1 PF06963.7 ETS63184.1 - 1.9e-135 451.6 11.5 2.3e-135 451.3 8.0 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Acyl-CoA_ox_N PF14749.1 ETS63185.1 - 1.6e-19 70.4 0.6 3e-19 69.5 0.4 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.14 ETS63185.1 - 3.5e-19 68.9 0.0 6.4e-18 64.7 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 ETS63185.1 - 1.5e-08 34.0 0.3 3.3e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 ETS63185.1 - 1.9e-05 24.7 0.1 5.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.9 ETS63186.1 - 1.3e-08 35.0 0.5 0.0004 20.3 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS63186.1 - 6.2e-08 32.9 0.7 0.00011 22.5 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS63186.1 - 5.4e-07 28.8 0.2 7.3e-06 25.1 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS63186.1 - 7.6e-06 25.0 3.7 0.00048 19.1 0.1 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS63186.1 - 2.5e-05 24.4 0.3 0.17 11.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS63186.1 - 0.00017 20.7 0.1 0.0047 16.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 ETS63186.1 - 0.00087 17.8 2.4 0.28 9.5 0.0 3.4 3 1 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 ETS63186.1 - 0.0019 18.2 0.5 0.0084 16.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS63186.1 - 0.0039 16.1 0.9 0.31 9.8 0.1 2.7 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 ETS63186.1 - 0.028 14.1 3.1 1.9 8.2 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS63186.1 - 0.032 12.8 0.1 0.032 12.8 0.1 1.8 3 0 0 3 3 3 0 Tryptophan halogenase Arrestin_C PF02752.17 ETS63187.1 - 4.5e-19 68.9 0.0 2.9e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS63187.1 - 5.6e-10 39.2 0.0 1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Sgf11 PF08209.6 ETS63188.1 - 8.3e-15 53.8 0.5 1.7e-14 52.7 0.4 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Cwf_Cwc_15 PF04889.7 ETS63188.1 - 2.9 7.5 16.9 0.55 9.8 1.6 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C2HC_2 PF13913.1 ETS63188.1 - 9.7 5.9 7.1 0.5 10.0 0.2 2.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type GFA PF04828.9 ETS63190.1 - 5.3e-20 71.1 0.4 7.3e-20 70.7 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 ETS63190.1 - 0.032 13.8 0.1 0.032 13.8 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal NOB1_Zn_bind PF08772.6 ETS63190.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.4 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 ETS63190.1 - 0.066 12.4 0.2 0.066 12.4 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 ETS63190.1 - 0.084 12.5 0.9 0.084 12.5 0.7 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_2 PF13240.1 ETS63190.1 - 0.21 11.1 0.3 0.21 11.1 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 ETS63190.1 - 0.41 10.4 8.4 11 5.9 5.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-LITAF-like PF10601.4 ETS63190.1 - 0.48 10.3 7.1 1 9.2 0.2 2.5 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 ETS63190.1 - 0.88 9.5 0.1 0.88 9.5 0.1 2.4 2 1 0 2 2 2 0 Zinc ribbon domain zf-NADH-PPase PF09297.6 ETS63190.1 - 5.2 6.6 9.2 0.5 9.9 0.3 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cyanate_lyase PF02560.9 ETS63191.1 - 2.4e-33 113.4 0.0 4e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 ETS63191.1 - 0.0009 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 ETS63191.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix DUF373 PF04123.8 ETS63191.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Zn_clus PF00172.13 ETS63192.1 - 1e-06 28.5 7.0 2.1e-06 27.5 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.7 ETS63192.1 - 0.14 11.8 0.0 0.42 10.2 0.0 1.8 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DNA_pol_viral_N PF00242.12 ETS63193.1 - 7.1 5.5 14.1 9.9 5.0 9.8 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain zf-3CxxC PF13695.1 ETS63194.1 - 0.019 15.1 0.1 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding domain Collagen PF01391.13 ETS63194.1 - 0.056 12.9 36.9 0.25 10.9 25.6 2.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) NAD_binding_2 PF03446.10 ETS63195.1 - 2.4e-37 128.3 2.1 3.5e-37 127.7 1.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS63195.1 - 2.1e-33 115.0 3.2 2.3e-33 114.8 0.5 2.2 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 ETS63195.1 - 7.2e-05 22.5 0.3 0.00017 21.3 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ETS63195.1 - 0.00016 22.0 0.7 0.00016 22.0 0.5 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ETS63195.1 - 0.00052 19.2 0.0 0.00088 18.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 ETS63195.1 - 0.063 12.6 0.2 0.063 12.6 0.1 1.8 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 ETS63195.1 - 0.075 12.4 0.1 0.2 10.9 0.0 1.6 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_DE PF00401.15 ETS63196.1 - 0.036 13.9 0.2 0.067 13.0 0.2 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Methyltransf_26 PF13659.1 ETS63197.1 - 4.2e-12 46.1 0.2 6.6e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS63197.1 - 1.6e-11 43.8 0.1 2.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETS63197.1 - 2.4e-06 27.1 0.0 3.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 ETS63197.1 - 1.4e-05 25.8 0.0 5.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS63197.1 - 5e-05 23.5 0.0 0.00016 22.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63197.1 - 0.003 18.1 0.1 0.0071 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 ETS63197.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 ETS63197.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 ETS63197.1 - 0.12 12.8 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETS63197.1 - 0.13 12.7 0.0 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 ETS63198.1 - 1.1e-51 175.8 0.0 3e-47 161.2 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Acyl_transf_1 PF00698.16 ETS63199.1 - 6e-17 61.9 1.0 3.7e-12 46.2 0.4 2.4 2 0 0 2 2 2 2 Acyl transferase domain MFS_1 PF07690.11 ETS63200.1 - 7.5e-32 110.3 60.7 8.2e-31 106.9 40.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily CoA_transf_3 PF02515.12 ETS63201.1 - 0.095 11.9 0.7 0.27 10.4 0.2 1.8 2 0 0 2 2 2 0 CoA-transferase family III ADH_N PF08240.7 ETS63202.1 - 4.6e-29 100.3 0.6 7.6e-29 99.6 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS63202.1 - 9.6e-27 93.0 0.5 1.5e-26 92.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63202.1 - 4.1e-08 34.1 0.6 1.2e-07 32.6 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_C PF02803.13 ETS63205.1 - 4.3e-09 35.8 0.5 9.6e-08 31.4 0.1 3.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 ETS63205.1 - 5.8e-09 35.3 0.1 2.6e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 ETS63205.1 - 2.9e-06 26.9 1.3 6.8e-06 25.7 0.9 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 ETS63205.1 - 0.00083 18.9 4.4 0.0037 16.9 0.3 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 ETS63205.1 - 0.012 14.1 0.3 0.07 11.5 0.2 2.0 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 ETS63205.1 - 0.046 13.5 1.7 0.54 10.1 0.0 3.0 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain GFO_IDH_MocA PF01408.17 ETS63207.1 - 3.2e-22 79.3 0.1 5.1e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 ETS63207.1 - 0.027 14.7 0.0 0.07 13.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CRCB PF02537.10 ETS63208.1 - 1.4e-30 105.5 16.7 6.8e-19 67.8 3.9 2.6 2 1 0 2 2 2 2 CrcB-like protein Acetyltransf_1 PF00583.19 ETS63209.1 - 0.0074 16.2 0.3 0.012 15.6 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETS63209.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNF2_N PF00176.18 ETS63211.1 - 4.7e-41 140.5 0.0 1.2e-40 139.2 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 ETS63211.1 - 6.8e-06 25.6 9.9 1.2e-05 24.8 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS63211.1 - 1.4e-05 24.9 13.2 2.5e-05 24.1 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS63211.1 - 3.4e-05 23.4 13.1 5.8e-05 22.6 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 ETS63211.1 - 6.5e-05 22.7 0.0 0.00027 20.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 ETS63211.1 - 0.00017 21.2 12.4 0.00028 20.5 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETS63211.1 - 0.00024 20.8 12.4 0.00042 20.0 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 ETS63211.1 - 0.17 11.7 10.4 0.32 10.9 7.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.1 ETS63211.1 - 0.28 10.9 4.2 0.71 9.6 2.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 ETS63211.1 - 0.3 10.6 5.5 1 8.9 3.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4501 PF14946.1 ETS63211.1 - 0.49 9.8 3.4 1.2 8.5 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) M20_dimer PF07687.9 ETS63213.1 - 4.9e-11 42.3 0.1 4.9e-11 42.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 ETS63213.1 - 4.2e-09 36.1 0.8 6.6e-09 35.5 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 NMO PF03060.10 ETS63214.1 - 1e-46 159.6 2.4 5.3e-46 157.2 1.7 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase DUF1275 PF06912.6 ETS63214.1 - 1.4e-25 89.7 10.3 2.5e-25 88.9 7.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) IMPDH PF00478.20 ETS63214.1 - 1.4e-08 34.0 1.4 0.001 18.0 0.8 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 ETS63214.1 - 0.0018 17.2 0.5 0.0044 15.9 0.3 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1109 PF06532.6 ETS63214.1 - 0.0053 16.1 2.5 0.0053 16.1 1.7 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1109) His_biosynth PF00977.16 ETS63214.1 - 0.02 14.1 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.12 ETS63214.1 - 0.039 13.0 0.1 0.073 12.1 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DUF543 PF04418.7 ETS63214.1 - 0.25 11.3 1.7 15 5.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) F-box-like PF12937.2 ETS63215.1 - 1.6e-10 40.5 1.4 7.3e-10 38.4 0.9 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS63215.1 - 0.0033 17.0 0.1 0.023 14.3 0.1 2.3 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.11 ETS63216.1 - 6.9e-42 143.4 34.3 6.9e-42 143.4 23.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS63216.1 - 8.8e-12 44.0 1.4 1.4e-11 43.3 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS63216.1 - 2.2e-11 43.0 26.8 1.6e-09 36.9 18.5 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4042 PF13251.1 ETS63218.1 - 1.5e-12 47.3 13.0 1.4e-09 37.6 0.2 5.6 6 1 1 7 7 7 2 Domain of unknown function (DUF4042) HEAT PF02985.17 ETS63218.1 - 0.00023 20.9 19.4 0.22 11.6 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 ETS63218.1 - 0.071 12.9 2.5 68 3.5 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS63218.1 - 0.095 12.9 40.1 0.26 11.5 0.3 7.6 5 2 3 8 8 8 0 HEAT repeats Cohesin_HEAT PF12765.2 ETS63218.1 - 0.16 11.9 4.5 1.2 9.1 0.4 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Pterin_4a PF01329.14 ETS63219.1 - 7e-27 93.0 0.4 1e-26 92.4 0.3 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sulfate_tra_GLY PF13792.1 ETS63220.1 - 0.0061 16.1 0.1 0.026 14.1 0.0 2.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif LRR_6 PF13516.1 ETS63221.1 - 0.0076 16.2 7.3 13 6.2 0.0 5.3 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.2 ETS63221.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 ETS63221.1 - 0.061 12.9 7.4 4.2 7.1 0.1 4.6 5 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS63221.1 - 0.1 12.6 6.6 8 6.9 0.1 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat Abhydrolase_5 PF12695.2 ETS63222.1 - 9.1e-19 67.6 0.5 1.3e-18 67.1 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS63222.1 - 3.9e-15 56.3 6.0 6.7e-15 55.5 4.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS63222.1 - 6.7e-11 42.1 0.4 9.9e-11 41.6 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 ETS63222.1 - 1.9e-08 34.1 0.3 2.7e-07 30.3 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 ETS63222.1 - 2e-07 30.7 0.0 3.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 ETS63222.1 - 7.9e-05 21.9 1.8 0.0009 18.5 0.8 2.5 1 1 1 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 ETS63222.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 ETS63222.1 - 0.0039 15.9 0.1 0.0056 15.4 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.3 ETS63222.1 - 0.011 15.6 0.1 0.035 13.9 0.0 1.9 2 0 0 2 2 1 0 Putative lysophospholipase Lipase PF00151.14 ETS63222.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Lipase DUF818 PF05677.7 ETS63222.1 - 0.024 13.4 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 ETS63222.1 - 0.047 12.9 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 ETS63222.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 ETS63222.1 - 0.12 11.7 0.0 3.1 7.1 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase HMGL-like PF00682.14 ETS63223.1 - 4.5e-41 141.0 0.0 8.1e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like PGG PF13962.1 ETS63223.1 - 0.025 14.2 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF3074 PF11274.3 ETS63224.1 - 7.9e-50 169.0 0.1 1.1e-49 168.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ham1p_like PF01725.11 ETS63227.1 - 5.2e-51 172.7 0.0 5.9e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family MFS_1 PF07690.11 ETS63228.1 - 3.9e-28 98.1 23.6 4.9e-28 97.8 16.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PRT_C PF08372.5 ETS63230.1 - 4.3e-05 23.0 0.3 0.16 11.4 0.0 2.6 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.3 ETS63230.1 - 0.00017 19.6 0.2 0.00017 19.6 0.1 3.0 5 0 0 5 5 5 1 Protein of unknown function (DUF3292) AAA_17 PF13207.1 ETS63230.1 - 0.00048 20.9 0.1 0.0059 17.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS63230.1 - 0.014 15.7 0.0 0.06 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 ETS63230.1 - 0.019 13.7 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 ETS63230.1 - 0.031 14.0 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 ETS63230.1 - 0.038 12.9 0.0 0.077 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Reticulon PF02453.12 ETS63230.1 - 0.046 13.3 8.1 0.42 10.1 0.5 2.5 2 0 0 2 2 2 0 Reticulon AAA_33 PF13671.1 ETS63230.1 - 0.057 13.3 0.1 0.71 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 ETS63230.1 - 0.086 11.6 0.0 0.87 8.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Methyltransf_23 PF13489.1 ETS63231.1 - 2.1e-05 24.3 0.0 5.3e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS63231.1 - 0.00086 18.9 0.0 0.79 9.3 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63231.1 - 0.0077 16.7 0.8 0.051 14.1 0.5 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS63231.1 - 0.014 15.4 1.2 0.12 12.4 0.8 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 ETS63231.1 - 0.05 13.9 0.0 2.5 8.5 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.11 ETS63231.1 - 0.11 10.8 0.0 0.68 8.1 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PRK PF00485.13 ETS63232.1 - 1.9e-52 177.6 0.0 1.9e-52 177.6 0.0 1.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 ETS63232.1 - 7.7e-45 152.6 0.1 1.3e-42 145.3 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 ETS63232.1 - 3e-08 34.0 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS63232.1 - 2.8e-06 28.1 0.0 5.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 ETS63232.1 - 0.00018 20.9 0.0 0.00045 19.6 0.0 1.6 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 ETS63232.1 - 0.00021 21.1 0.0 0.00077 19.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain CPT PF07931.7 ETS63232.1 - 0.00041 20.0 0.0 0.00082 19.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 ETS63232.1 - 0.04 13.6 0.7 40 4.0 0.0 3.6 3 0 0 3 3 3 0 Part of AAA domain Zeta_toxin PF06414.7 ETS63232.1 - 0.066 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 ETS63232.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.23 ETS63233.1 - 5.2e-10 38.9 0.0 8.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain hSac2 PF12456.3 ETS63234.1 - 2.2e-29 101.1 0.0 4.4e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase DUF667 PF05018.8 ETS63234.1 - 2e-07 30.4 0.0 5e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF667) Glyco_hydro_108 PF05838.7 ETS63234.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 108 Syja_N PF02383.13 ETS63235.1 - 1.4e-86 290.1 0.0 2.2e-86 289.5 0.0 1.3 1 1 0 1 1 1 1 SacI homology domain Polysacc_deac_1 PF01522.16 ETS63236.1 - 6e-30 103.4 0.0 1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Serglycin PF04360.7 ETS63236.1 - 1.5 8.5 6.6 0.23 11.1 0.6 2.2 2 0 0 2 2 2 0 Serglycin NUDE_C PF04880.8 ETS63236.1 - 7.6 6.8 12.8 0.13 12.6 0.9 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF2962 PF11176.3 ETS63237.1 - 7.8e-40 135.9 0.1 7.8e-40 135.9 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2962) RTA1 PF04479.8 ETS63238.1 - 5.5e-30 104.5 9.2 1.5e-25 90.0 2.4 2.3 2 0 0 2 2 2 2 RTA1 like protein DUF350 PF03994.9 ETS63238.1 - 0.003 17.2 0.8 0.003 17.2 0.6 3.6 3 1 0 3 3 3 1 Domain of Unknown Function (DUF350) Zn_clus PF00172.13 ETS63239.1 - 0.0031 17.4 7.7 0.0067 16.3 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Patatin PF01734.17 ETS63239.1 - 0.049 13.5 0.3 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 Patatin-like phospholipase GMC_oxred_N PF00732.14 ETS63240.1 - 6e-42 143.7 0.1 1.1e-41 142.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS63240.1 - 1.5e-21 77.1 0.3 9.2e-21 74.6 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS63240.1 - 2.7e-06 26.5 3.1 0.025 13.4 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 ETS63240.1 - 0.00014 21.0 0.6 0.00022 20.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS63240.1 - 0.0011 18.8 0.4 0.014 15.2 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS63240.1 - 0.0023 16.8 3.4 0.26 10.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS63240.1 - 0.045 13.7 1.5 0.13 12.3 1.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 ETS63240.1 - 0.067 13.0 1.1 0.41 10.4 1.1 2.0 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 ETS63240.1 - 0.12 11.4 0.4 0.21 10.6 0.3 1.3 1 0 0 1 1 1 0 Thi4 family MatE PF01554.13 ETS63241.1 - 1.4e-52 177.5 26.8 2.1e-31 108.7 6.7 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 ETS63241.1 - 1.2e-07 31.6 9.5 1.2e-07 31.6 6.6 3.7 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain Acetyltransf_1 PF00583.19 ETS63242.1 - 2.1e-12 46.8 0.1 3.1e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS63242.1 - 4e-11 42.9 0.0 5.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS63242.1 - 2.7e-06 27.4 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS63242.1 - 3.6e-05 23.9 0.0 4.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS63242.1 - 0.00019 21.4 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS63242.1 - 0.0068 16.3 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Amidohydro_2 PF04909.9 ETS63243.1 - 2.6e-41 141.9 3.6 3.7e-41 141.4 1.3 1.9 2 0 0 2 2 2 1 Amidohydrolase MFS_1 PF07690.11 ETS63245.1 - 1.8e-30 105.8 29.3 4.2e-30 104.6 20.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 ETS63245.1 - 1.9e-22 80.2 4.2 4e-22 79.2 2.9 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63245.1 - 2.1e-09 37.2 0.1 6e-09 35.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63245.1 - 6.8e-05 22.5 0.2 0.00023 20.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 ETS63245.1 - 8.6e-05 22.8 0.2 0.00019 21.7 0.1 1.6 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 ETS63245.1 - 0.0015 18.3 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 ETS63245.1 - 0.0037 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 ETS63245.1 - 0.0057 16.2 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.7 ETS63245.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.2 ETS63245.1 - 0.085 11.7 0.1 0.19 10.5 0.1 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme TMEM237 PF15383.1 ETS63245.1 - 0.8 8.7 2.2 1.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 237 Sugar_tr PF00083.19 ETS63246.1 - 1.6e-49 168.7 18.3 2.4e-49 168.1 12.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 ETS63246.1 - 9.6e-34 116.7 0.1 1.6e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 ETS63246.1 - 1.4e-25 89.7 24.8 1.4e-14 53.6 5.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DLH PF01738.13 ETS63246.1 - 0.00052 19.3 0.1 0.0047 16.2 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS63246.1 - 0.025 14.3 0.6 0.05 13.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family NOA36 PF06524.7 ETS63246.1 - 4.3 6.5 4.7 10 5.2 3.2 1.5 1 0 0 1 1 1 0 NOA36 protein TPMT PF05724.6 ETS63249.1 - 5.5e-27 94.6 0.0 6.8e-23 81.2 0.0 2.1 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 ETS63249.1 - 3e-07 30.4 0.1 4.6e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS63249.1 - 1.7e-06 27.7 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS63249.1 - 3.9e-06 27.2 0.0 5.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS63249.1 - 4.9e-06 26.8 0.0 7.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63249.1 - 1.1e-05 25.9 0.0 2.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS63249.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS63249.1 - 0.00016 22.0 0.0 0.00028 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_92 PF07971.7 ETS63250.1 - 1.9e-113 379.7 0.0 2.7e-113 379.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF2540 PF10802.3 ETS63251.1 - 0.0039 16.8 0.3 0.0071 15.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2540) Oxidored_FMN PF00724.15 ETS63254.1 - 5.3e-49 167.0 0.0 1.1e-48 165.9 0.0 1.4 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.19 ETS63255.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS63255.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS63255.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS63255.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein adh_short PF00106.20 ETS63256.1 - 2.2e-29 102.5 1.8 3.2e-29 101.9 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS63256.1 - 4.9e-14 52.3 1.7 8.1e-14 51.6 1.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS63256.1 - 4.8e-07 29.7 0.0 6.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS63256.1 - 0.0023 17.4 0.1 0.0033 16.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glutaredoxin PF00462.19 ETS63256.1 - 0.086 12.8 0.0 1.5 8.8 0.0 2.6 2 1 1 3 3 3 0 Glutaredoxin 2-Hacid_dh_C PF02826.14 ETS63256.1 - 0.1 11.7 0.2 0.28 10.3 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS63256.1 - 0.15 12.0 0.9 0.27 11.2 0.6 1.5 1 0 0 1 1 1 0 NADH(P)-binding Tub_2 PF04525.7 ETS63258.1 - 1.3e-18 67.0 0.0 1.6e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 DUF1295 PF06966.7 ETS63259.1 - 1.5e-51 174.9 0.2 2.3e-51 174.3 0.1 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETS63259.1 - 4.7e-06 26.7 0.0 2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 ETS63259.1 - 6.7e-05 22.6 0.1 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 ETS63259.1 - 0.00033 20.7 2.3 0.00041 20.4 0.0 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF3382 PF11862.3 ETS63259.1 - 0.074 12.9 0.4 0.4 10.6 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Choline_transpo PF04515.7 ETS63260.1 - 6.2e-88 294.7 28.5 6.2e-88 294.7 19.7 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Nse5 PF08691.5 ETS63260.1 - 0.19 10.1 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 AMP-binding PF00501.23 ETS63261.1 - 1.6e-66 224.4 0.0 2e-64 217.5 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 ETS63261.1 - 0.00016 22.5 0.0 0.00044 21.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YukC PF10140.4 ETS63262.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Fungal_trans_2 PF11951.3 ETS63263.1 - 1.1e-39 136.1 0.4 4.3e-39 134.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DnaJ PF00226.26 ETS63263.1 - 1.3e-20 72.8 4.1 2.7e-20 71.8 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 ETS63263.1 - 2e-15 56.5 14.0 2e-15 56.5 9.7 2.2 2 0 0 2 2 2 1 DnaJ central domain CTDII PF01556.13 ETS63263.1 - 3.6e-14 52.3 0.0 8.6e-13 47.9 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain Zn_clus PF00172.13 ETS63263.1 - 8.9e-06 25.5 12.3 8.9e-06 25.5 8.5 2.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A2L_zn_ribbon PF08792.5 ETS63263.1 - 0.11 11.9 0.1 0.11 11.9 0.0 3.2 3 1 1 4 4 4 0 A2L zinc ribbon domain Indigoidine_A PF04227.7 ETS63264.1 - 7.7e-115 383.1 0.2 1.1e-114 382.6 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 ETS63264.1 - 3.6e-22 78.8 2.0 4.1e-21 75.3 1.4 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RTX_C PF08339.5 ETS63264.1 - 0.12 12.0 0.3 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 RTX C-terminal domain AP_endonuc_2 PF01261.19 ETS63265.1 - 4.6e-16 58.7 0.0 3.4e-11 42.8 0.0 2.6 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel Glyoxalase_2 PF12681.2 ETS63267.1 - 2.9e-19 69.6 0.0 7e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ETS63267.1 - 0.00078 19.4 0.0 0.0069 16.3 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2574 PF10836.3 ETS63267.1 - 0.21 11.3 1.8 0.7 9.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2574) AFG1_ATPase PF03969.11 ETS63268.1 - 2.3e-88 296.4 0.0 7.8e-86 288.1 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 ETS63268.1 - 2.2e-06 27.8 0.0 1.2e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS63268.1 - 2.6e-06 27.5 0.2 4.1e-05 23.6 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 ETS63268.1 - 0.0018 18.4 0.1 0.011 15.9 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 ETS63268.1 - 0.011 15.4 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 ETS63268.1 - 0.061 13.5 0.0 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF2638 PF10937.3 ETS63268.1 - 2.1 9.4 5.8 0.58 11.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) GDPD PF03009.12 ETS63270.1 - 8.5e-32 110.6 0.0 1.4e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family p450 PF00067.17 ETS63271.1 - 1.2e-82 277.8 0.0 1.5e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.15 ETS63272.1 - 5.8e-50 169.7 15.4 7.6e-50 169.3 10.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.13 ETS63272.1 - 0.037 13.5 2.8 0.041 13.3 0.0 2.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain GAS PF13851.1 ETS63272.1 - 0.18 10.9 0.3 0.28 10.3 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PTPLA PF04387.9 ETS63273.1 - 4.7e-53 178.9 5.7 7.9e-53 178.2 4.0 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SQS_PSY PF00494.14 ETS63274.1 - 2e-52 178.1 0.4 3.1e-52 177.5 0.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase PUA PF01472.15 ETS63275.1 - 1.2e-20 72.9 0.3 7.1e-20 70.5 0.1 2.0 2 0 0 2 2 2 1 PUA domain MRG PF05712.8 ETS63275.1 - 0.016 14.1 0.1 1.5 7.6 0.0 2.2 1 1 1 2 2 2 0 MRG Arch_ATPase PF01637.13 ETS63276.1 - 0.00016 21.4 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 ETS63276.1 - 0.0016 18.5 0.4 0.013 15.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Nucleoplasmin PF03066.10 ETS63276.1 - 0.055 12.9 1.5 0.12 11.9 1.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 ETS63276.1 - 3 8.1 8.4 1.1 9.5 2.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 ETS63276.1 - 3.2 5.5 6.8 5.6 4.7 3.3 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nop14 PF04147.7 ETS63276.1 - 4.7 4.9 5.9 6.4 4.5 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Amidase PF01425.16 ETS63277.1 - 5.4e-89 299.0 0.0 7.8e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Seryl_tRNA_N PF02403.17 ETS63277.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-DNL PF05180.7 ETS63278.1 - 1.8e-29 101.2 0.3 2.8e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 DNL zinc finger DUF706 PF05153.10 ETS63279.1 - 5.3e-121 402.7 0.6 6.7e-121 402.3 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 ETS63279.1 - 0.0084 16.1 0.5 1.4 8.9 0.0 2.7 3 0 0 3 3 3 2 HD domain Pro_dh PF01619.13 ETS63281.1 - 1.8e-36 125.7 0.0 1.7e-18 66.6 0.0 3.7 2 1 0 2 2 2 2 Proline dehydrogenase PQ-loop PF04193.9 ETS63282.1 - 2.2e-18 65.5 23.1 2.7e-10 39.6 4.4 3.5 4 0 0 4 4 4 2 PQ loop repeat Syndecan PF01034.15 ETS63282.1 - 0.059 13.0 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Syndecan domain DUF4310 PF14187.1 ETS63283.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) COPI_assoc PF08507.5 ETS63283.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 COPI associated protein Fungal_trans PF04082.13 ETS63284.1 - 1.1e-06 27.7 3.1 8.6e-05 21.5 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63284.1 - 4.3e-05 23.3 7.3 7.4e-05 22.5 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF793 PF05633.6 ETS63284.1 - 0.12 11.0 1.8 0.31 9.7 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF793) MFS_1 PF07690.11 ETS63285.1 - 7.6e-37 126.8 47.4 7.6e-37 126.8 32.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS63285.1 - 9.6e-09 34.3 12.7 9.6e-09 34.3 8.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 ETS63285.1 - 0.025 12.6 1.3 0.38 8.7 0.6 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cofilin_ADF PF00241.15 ETS63285.1 - 0.12 12.2 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein DUF4381 PF14316.1 ETS63285.1 - 0.76 9.8 0.0 0.76 9.8 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4381) Sdh5 PF03937.11 ETS63286.1 - 5.4e-25 86.8 0.2 8e-25 86.3 0.1 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Pyr_redox_2 PF07992.9 ETS63288.1 - 1.6e-25 90.2 9.4 2.7e-23 82.9 6.5 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 ETS63288.1 - 2.3e-13 49.4 0.0 5.9e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 ETS63288.1 - 2.5e-13 50.5 0.6 6.9e-08 32.7 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS63288.1 - 4.2e-13 49.5 9.9 2.4e-11 43.8 1.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS63288.1 - 1.1e-05 24.5 0.5 0.078 11.8 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 ETS63288.1 - 0.00016 21.8 0.0 0.0022 18.2 0.0 2.6 2 0 0 2 2 2 1 Reductase C-terminal GIDA PF01134.17 ETS63288.1 - 0.0012 17.7 1.2 0.03 13.1 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 ETS63288.1 - 0.0032 17.2 2.5 0.041 13.6 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 ETS63288.1 - 0.0095 16.1 6.0 0.12 12.6 0.3 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding Rieske_2 PF13806.1 ETS63288.1 - 0.025 14.2 0.0 0.087 12.5 0.0 2.0 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain TrkA_N PF02254.13 ETS63288.1 - 0.44 10.5 2.9 4.3 7.3 0.2 2.6 2 0 0 2 2 2 0 TrkA-N domain Transaldolase PF00923.14 ETS63289.1 - 1.5e-44 152.2 0.2 2.3e-44 151.6 0.1 1.3 1 0 0 1 1 1 1 Transaldolase PolC_DP2 PF03833.8 ETS63290.1 - 0.076 10.6 0.4 0.1 10.2 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DnaJ PF00226.26 ETS63291.1 - 3.4e-16 58.7 1.9 6.9e-16 57.7 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2924 PF11149.3 ETS63291.1 - 0.25 11.3 5.8 0.11 12.5 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) LcrG PF07216.7 ETS63291.1 - 4.8 7.2 7.2 2.6 8.1 1.9 2.5 2 1 0 2 2 2 0 LcrG protein SDH_alpha PF03313.10 ETS63292.1 - 2.1e-101 338.7 0.3 3.4e-101 337.9 0.2 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 ETS63292.1 - 2.1e-52 177.3 0.0 5.1e-52 176.1 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain zf-rbx1 PF12678.2 ETS63292.1 - 8.6e-07 28.9 2.2 1.7e-06 28.0 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 ETS63292.1 - 0.00022 20.9 6.4 0.00022 20.9 4.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETS63292.1 - 0.00097 18.7 3.3 0.0022 17.6 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS63292.1 - 0.069 12.8 4.1 0.14 11.9 2.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 ETS63292.1 - 0.24 11.4 2.7 9.7 6.2 1.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 ETS63292.1 - 0.88 9.4 3.7 0.92 9.3 1.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 ETS63292.1 - 1.7 8.7 7.5 0.36 10.9 2.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS63292.1 - 2.4 7.8 6.1 7.1 6.3 4.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 ETS63293.1 - 0.0034 17.2 7.0 0.0063 16.3 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_8 PF13523.1 ETS63294.1 - 3.6e-34 117.8 0.1 5.6e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 ETS63295.1 - 5.7e-34 116.4 0.7 8.1e-34 115.9 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63295.1 - 3.2e-10 40.9 0.0 5.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS63295.1 - 2.6e-06 27.1 0.0 6.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 ETS63295.1 - 0.0018 17.8 0.2 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_FMN PF00724.15 ETS63296.1 - 2.4e-55 187.9 0.0 1.4e-54 185.3 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2034 PF10356.4 ETS63297.1 - 2.4e-19 69.2 1.1 1.3e-10 40.7 0.1 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 ETS63297.1 - 9e-08 31.9 0.0 1.6e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Restriction endonuclease TPR_11 PF13414.1 ETS63298.1 - 9.6e-24 82.8 8.8 1.5e-10 40.6 0.3 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETS63298.1 - 1.1e-18 65.9 6.4 2.1e-06 27.0 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS63298.1 - 1.5e-17 62.0 7.9 5.6e-07 29.0 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETS63298.1 - 1.9e-13 50.6 4.9 1.8e-07 31.6 0.2 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS63298.1 - 2.6e-13 49.6 8.1 9.3e-06 25.5 0.0 3.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETS63298.1 - 1.4e-12 46.7 6.3 0.0044 17.1 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS63298.1 - 7.8e-12 44.7 8.0 0.00036 20.9 0.1 4.7 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETS63298.1 - 8.7e-12 45.2 5.7 6.8e-06 26.3 0.3 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS63298.1 - 1.7e-09 36.7 5.2 0.067 13.0 0.0 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS63298.1 - 1.8e-09 36.6 4.9 0.02 14.6 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS63298.1 - 3.3e-06 27.1 2.3 0.025 15.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS63298.1 - 7.4e-05 22.5 3.2 0.0035 17.1 0.2 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETS63298.1 - 8.5e-05 21.7 1.7 8.5e-05 21.7 1.2 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS63298.1 - 0.00016 21.7 5.3 0.031 14.4 0.2 3.0 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 ETS63298.1 - 0.0055 16.7 6.4 0.033 14.2 0.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS63298.1 - 0.018 14.9 13.5 1.6 8.7 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 ETS63298.1 - 0.038 13.1 2.0 0.16 11.1 0.9 2.1 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP HSCB_C PF07743.8 ETS63298.1 - 4.9 7.6 7.7 3 8.3 1.5 2.8 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF3767 PF12597.3 ETS63299.1 - 3.2e-25 88.0 0.1 3.9e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) SUR7 PF06687.7 ETS63300.1 - 8.6e-09 35.2 8.1 2.1e-08 33.9 5.6 1.6 1 1 0 1 1 1 1 SUR7/PalI family EphA2_TM PF14575.1 ETS63301.1 - 0.0063 16.8 0.0 0.0088 16.4 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain NfeD PF01957.13 ETS63301.1 - 0.038 14.1 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4179 PF13786.1 ETS63301.1 - 0.047 13.9 0.1 0.063 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Sec66 PF09802.4 ETS63301.1 - 0.06 12.7 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF347 PF03988.7 ETS63301.1 - 0.1 12.5 0.7 0.16 11.8 0.5 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.5 ETS63301.1 - 0.21 10.9 3.6 0.3 10.4 2.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 ETS63301.1 - 6 7.0 8.6 9.7 6.3 5.9 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator ALO PF04030.9 ETS63302.1 - 1.1e-71 241.5 1.7 2e-62 211.1 0.1 2.9 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 ETS63302.1 - 4.5e-19 68.2 0.1 9e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Yeast-kill-tox PF09207.6 ETS63303.1 - 0.26 11.7 2.9 3.7 8.0 0.2 2.8 3 0 0 3 3 3 0 Yeast killer toxin EI24 PF07264.6 ETS63304.1 - 1.4e-30 106.4 8.9 1.9e-30 105.9 6.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Aa_trans PF01490.13 ETS63306.1 - 1.2e-52 178.7 39.3 1.4e-52 178.5 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HIG_1_N PF04588.8 ETS63307.1 - 3e-19 68.5 0.1 4.2e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3168 PF11367.3 ETS63308.1 - 0.043 13.9 1.5 1 9.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3168) MFS_1 PF07690.11 ETS63309.1 - 1.6e-26 92.8 27.0 1.6e-26 92.8 18.7 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS63309.1 - 0.00069 19.5 8.5 0.03 14.3 1.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) DUF3452 PF11934.3 ETS63309.1 - 4 6.7 5.6 4.5 6.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Rhodanese PF00581.15 ETS63310.1 - 2.3e-16 60.1 0.0 3.7e-09 36.9 0.0 3.1 2 1 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.1 ETS63310.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain Sugar_tr PF00083.19 ETS63311.1 - 6.3e-118 394.2 29.2 7.2e-118 394.0 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS63311.1 - 5.1e-25 87.9 44.4 1.3e-21 76.7 5.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 ETS63311.1 - 0.3 11.1 3.4 1.2 9.2 1.1 2.5 2 0 0 2 2 2 0 Phage holin family 2 TMEM190 PF15431.1 ETS63312.1 - 0.023 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 HAMP PF00672.20 ETS63312.1 - 0.066 13.3 0.6 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 HAMP domain MGC-24 PF05283.6 ETS63312.1 - 2.2 8.0 26.1 0.02 14.7 10.3 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Asp PF00026.18 ETS63313.1 - 2.4e-45 155.1 15.2 8.6e-45 153.3 10.5 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 ETS63313.1 - 2.7e-06 27.7 2.2 0.013 16.0 0.5 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 ETS63313.1 - 0.00033 20.6 9.2 0.0076 16.2 3.8 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 ETS63313.1 - 0.0013 18.2 0.0 0.006 16.1 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Ribonuc_L-PSP PF01042.16 ETS63316.1 - 8.2e-38 128.8 0.1 1.4e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP SET PF00856.23 ETS63318.1 - 0.00068 19.9 1.6 0.092 13.0 0.0 3.3 1 1 2 3 3 3 1 SET domain Spore_coat_CotO PF14153.1 ETS63318.1 - 0.0079 15.6 2.5 0.014 14.8 1.7 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 ETS63318.1 - 1 6.9 2.0 1.4 6.5 1.4 1.1 1 0 0 1 1 1 0 Ycf1 SDA1 PF05285.7 ETS63318.1 - 9.8 5.3 21.3 17 4.5 14.7 1.2 1 0 0 1 1 1 0 SDA1 zf-UBR PF02207.15 ETS63319.1 - 7e-16 57.7 14.9 7e-16 57.7 10.3 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 ETS63319.1 - 3.2e-10 39.6 0.0 8.6e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UBA_4 PF14555.1 ETS63319.1 - 0.049 13.1 0.1 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain MSP1_C PF07462.6 ETS63319.1 - 0.067 11.5 1.0 0.11 10.8 0.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Fungal_trans PF04082.13 ETS63320.1 - 1.2e-14 53.7 1.0 1.9e-14 53.2 0.0 1.8 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63320.1 - 1.6e-07 31.1 8.8 2.9e-07 30.2 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA_3 PF07730.8 ETS63320.1 - 0.18 12.2 4.4 0.12 12.7 0.4 2.7 2 0 0 2 2 2 0 Histidine kinase ICE2 PF08426.5 ETS63321.1 - 1.1e-55 189.0 0.7 4.9e-29 101.1 0.0 3.8 2 2 2 4 4 4 3 ICE2 DS PF01916.12 ETS63322.1 - 2e-133 444.1 0.0 2.3e-133 443.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF494 PF04361.8 ETS63322.1 - 0.0033 17.1 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF494) Abhydrolase_5 PF12695.2 ETS63323.1 - 0.00083 19.1 0.8 0.00083 19.1 0.6 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS63323.1 - 0.0016 18.3 0.2 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS63323.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 ETS63323.1 - 0.082 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 ETS63323.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF818 PF05677.7 ETS63323.1 - 0.18 10.5 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) EXS PF03124.9 ETS63324.1 - 2.5e-74 250.3 0.1 3e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 EXS family DUF775 PF05603.7 ETS63325.1 - 9e-38 129.8 0.0 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Nop16 PF09420.5 ETS63326.1 - 2.3e-41 141.6 0.2 2.7e-41 141.4 0.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Xan_ur_permease PF00860.15 ETS63327.1 - 2.8e-60 203.8 26.2 5.6e-60 202.8 18.2 1.4 1 0 0 1 1 1 1 Permease family ATG_C PF09333.6 ETS63328.1 - 2.8 8.1 4.5 1.4 9.1 1.7 1.7 2 0 0 2 2 2 0 ATG C terminal domain C5-epim_C PF06662.8 ETS63329.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Lyase_aromatic PF00221.14 ETS63330.1 - 5.4e-161 536.2 1.1 6.8e-161 535.8 0.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Epimerase PF01370.16 ETS63331.1 - 1.5e-18 67.0 0.0 2.5e-18 66.3 0.0 1.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS63331.1 - 6e-11 41.5 0.0 8.1e-11 41.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS63331.1 - 1.1e-09 37.5 0.0 3.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 ETS63331.1 - 9.6e-09 34.5 0.0 1.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETS63331.1 - 5.2e-05 23.2 0.0 0.00016 21.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS63331.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS63331.1 - 0.053 12.4 0.0 0.67 8.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Hydantoinase_B PF02538.9 ETS63332.1 - 4.5e-187 622.4 0.0 1.3e-186 620.9 0.0 1.6 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Proteasome_A_N PF10584.4 ETS63332.1 - 0.3 10.4 1.4 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Sporozoite_P67 PF05642.6 ETS63333.1 - 8 4.1 12.9 10 3.7 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_Helicase PF02689.9 ETS63334.1 - 0.023 12.4 0.1 0.039 11.7 0.1 1.3 1 0 0 1 1 1 0 Helicase ARGLU PF15346.1 ETS63334.1 - 0.65 9.7 27.5 1.3 8.8 19.1 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Form_Nir_trans PF01226.12 ETS63335.1 - 9.6e-64 214.6 20.4 1.5e-63 213.9 14.2 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter HECT PF00632.20 ETS63335.1 - 1.9e-32 112.6 0.0 8e-32 110.6 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Myc_N PF01056.13 ETS63335.1 - 0.092 11.8 10.2 0.15 11.2 7.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RRF PF01765.14 ETS63336.1 - 1.2e-42 145.2 0.1 1.7e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor TRAM_LAG1_CLN8 PF03798.11 ETS63337.1 - 2e-30 105.8 11.7 2.6e-30 105.4 8.1 1.1 1 0 0 1 1 1 1 TLC domain Smr PF01713.16 ETS63338.1 - 9.4e-12 44.9 1.9 1.4e-11 44.4 0.1 2.2 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 ETS63338.1 - 1.2e-08 34.2 0.7 0.00021 20.7 0.0 4.0 4 0 0 4 4 4 2 CUE domain Oxidored-like PF09791.4 ETS63339.1 - 1.7e-06 27.3 8.9 4.6e-06 25.9 6.2 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Abhydrolase_6 PF12697.2 ETS63339.1 - 3.6e-06 27.0 2.0 1e-05 25.5 0.3 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63339.1 - 4.1e-06 26.6 0.0 1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63339.1 - 0.016 14.7 0.7 0.2 11.1 0.1 2.5 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF3436 PF11918.3 ETS63340.1 - 0.044 14.0 0.1 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) adh_short PF00106.20 ETS63341.1 - 5.9e-27 94.6 1.4 8e-27 94.1 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS63341.1 - 3.5e-24 85.9 0.9 4.3e-24 85.6 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS63341.1 - 7.8e-10 38.6 1.3 1.9e-09 37.4 0.9 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS63341.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1657 PF07870.6 ETS63341.1 - 0.044 13.4 0.7 0.084 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) ThiF PF00899.16 ETS63341.1 - 0.08 12.7 1.5 2.4 7.9 0.2 2.4 1 1 1 2 2 2 0 ThiF family Methyltransf_25 PF13649.1 ETS63341.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPRTase PF14681.1 ETS63342.1 - 3.1e-70 235.6 0.0 3.5e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 ETS63342.1 - 0.00097 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.11 ETS63343.1 - 3.1e-21 75.4 44.1 7.1e-15 54.5 16.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS63343.1 - 3.1e-16 59.0 26.6 9.8e-16 57.3 6.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1840 PF08895.6 ETS63343.1 - 0.46 10.5 2.8 0.92 9.5 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DJ-1_PfpI PF01965.19 ETS63344.1 - 4.1e-25 87.9 0.0 7e-25 87.1 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 ETS63344.1 - 1.1e-16 60.0 0.0 1.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family adh_short PF00106.20 ETS63345.1 - 9.1e-24 84.2 0.0 1.3e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS63345.1 - 2.2e-10 40.5 0.0 2.9e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS63345.1 - 4.8e-06 26.5 0.0 6.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS63345.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS63345.1 - 0.0052 16.2 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 ETS63345.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 ETS63345.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 ETS63345.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ETS63345.1 - 0.04 13.5 0.0 0.098 12.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zip PF02535.17 ETS63346.1 - 1.7e-53 181.6 15.3 2.3e-53 181.2 10.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter GerE PF00196.14 ETS63346.1 - 0.074 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 ETS63346.1 - 0.076 12.5 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 ETS63346.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 ETS63346.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 ETS63347.1 - 1e-07 31.2 0.0 1.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.1 ETS63347.1 - 5e-06 25.9 0.0 9.8e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 ETS63347.1 - 2.8e-05 23.6 0.1 5.2e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.11 ETS63347.1 - 5.5e-05 22.3 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_7 PF02796.10 ETS63347.1 - 0.00057 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase GerE PF00196.14 ETS63347.1 - 0.0094 15.2 0.0 0.021 14.0 0.0 1.6 1 1 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_32 PF13565.1 ETS63347.1 - 0.016 15.9 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Terminase_5 PF06056.7 ETS63347.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.1 ETS63347.1 - 0.035 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3760 PF12586.3 ETS63348.1 - 0.0082 15.9 2.3 0.0082 15.9 1.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3760) F-box-like PF12937.2 ETS63348.1 - 0.18 11.5 1.4 0.46 10.2 1.0 1.8 1 0 0 1 1 1 0 F-box-like Ytp1 PF10355.4 ETS63349.1 - 3.5e-80 269.0 15.2 3.5e-80 269.0 10.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 ETS63349.1 - 5.8e-29 99.7 2.8 5.8e-29 99.7 2.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Fungal_trans PF04082.13 ETS63350.1 - 7.5e-19 67.6 0.1 1.6e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 ETS63350.1 - 4.5e-05 23.4 20.0 7.8e-05 22.7 0.3 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS63350.1 - 6.6e-05 23.0 11.1 0.0027 17.9 0.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 ETS63350.1 - 7.5e-05 22.5 5.7 7.5e-05 22.5 4.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC_2 PF13913.1 ETS63350.1 - 0.037 13.7 8.6 0.17 11.5 0.2 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 ETS63350.1 - 3.5 8.0 8.8 6 7.3 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain TerY-C PF15616.1 ETS63350.1 - 4.3 7.2 6.6 0.65 9.9 0.1 2.6 3 0 0 3 3 3 0 TerY-C metal binding domain MFS_1 PF07690.11 ETS63351.1 - 5e-18 64.9 27.3 5e-18 64.9 19.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S15 PF02129.13 ETS63352.1 - 3.1e-33 115.3 0.0 7.9e-32 110.7 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS63352.1 - 6.3e-28 98.1 0.0 8.5e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS63352.1 - 0.00034 20.5 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1479 PF07350.7 ETS63353.1 - 1.4e-05 23.7 0.1 0.00018 20.1 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1479) PhyH PF05721.8 ETS63353.1 - 0.00013 22.0 0.0 0.0027 17.7 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 ETS63353.1 - 0.0012 19.3 0.0 0.0026 18.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.11 ETS63353.1 - 0.0023 17.6 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_5 PF13759.1 ETS63353.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CTP_transf_2 PF01467.21 ETS63354.1 - 2.2e-14 53.8 0.3 6.4e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase Innate_immun PF12782.2 ETS63354.1 - 0.078 12.1 11.8 0.19 10.9 8.2 1.6 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family CPSF73-100_C PF11718.3 ETS63354.1 - 9 5.5 8.9 20 4.4 6.2 1.5 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MMtag PF10159.4 ETS63355.1 - 8.8e-30 102.5 2.7 8.8e-30 102.5 1.9 2.7 2 1 1 3 3 3 1 Kinase phosphorylation protein Hex_IIIa PF02455.11 ETS63355.1 - 3.6 6.1 8.3 4.4 5.8 5.8 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Zip PF02535.17 ETS63355.1 - 3.6 6.4 4.9 4.5 6.1 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter IMS PF00817.15 ETS63356.1 - 5e-39 133.4 0.0 9e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETS63356.1 - 4.1e-10 39.6 0.1 4.1e-09 36.4 0.0 2.5 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain Glyco_hydro_cc PF11790.3 ETS63357.1 - 5.1e-68 229.0 4.3 6.1e-68 228.8 3.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 ETS63357.1 - 0.0012 17.7 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_39 PF01229.12 ETS63357.1 - 0.083 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 MFS_1 PF07690.11 ETS63358.1 - 1.9e-22 79.5 38.1 4.3e-13 48.6 13.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Neurensin PF14927.1 ETS63358.1 - 0.016 14.5 3.4 0.057 12.8 0.0 3.3 4 0 0 4 4 4 0 Neurensin Alpha-amylase PF00128.19 ETS63359.1 - 5.6e-75 252.6 0.1 8.6e-75 252.0 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 ETS63359.1 - 6e-14 51.8 0.4 1.6e-13 50.5 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) PAN_4 PF14295.1 ETS63360.1 - 0.016 14.8 0.1 0.066 12.9 0.1 2.0 1 0 0 1 1 1 0 PAN domain Cu-oxidase_2 PF07731.9 ETS63361.1 - 2.9e-39 133.7 5.6 1.2e-36 125.2 1.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS63361.1 - 2.5e-38 131.4 0.1 3.6e-35 121.2 0.1 2.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS63361.1 - 2.1e-31 108.0 0.7 2e-26 92.0 0.1 4.1 4 0 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.1 ETS63361.1 - 0.15 12.0 0.0 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Cupredoxin-like domain FTR1 PF03239.9 ETS63362.1 - 1.6e-53 181.6 7.4 1.5e-35 122.6 3.0 2.1 2 0 0 2 2 2 2 Iron permease FTR1 family Wzy_C PF04932.10 ETS63362.1 - 0.00056 19.7 2.2 0.0044 16.8 0.3 2.4 2 0 0 2 2 2 1 O-Antigen ligase DUF2721 PF11026.3 ETS63362.1 - 0.014 15.0 0.6 0.014 15.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) IncA PF04156.9 ETS63363.1 - 0.069 12.7 0.0 2.7 7.5 0.0 2.3 2 1 0 2 2 2 0 IncA protein adh_short PF00106.20 ETS63364.1 - 8.3e-30 103.8 0.1 1.3e-29 103.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS63364.1 - 5.8e-29 101.5 0.0 7.5e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS63364.1 - 1e-14 54.6 0.1 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS63364.1 - 0.0068 15.8 0.3 0.021 14.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS63364.1 - 0.0076 15.1 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Dak1 PF02733.12 ETS63365.1 - 2.9e-108 361.3 0.0 3.7e-108 360.9 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 ETS63365.1 - 1.2e-43 148.7 0.8 1.2e-43 148.7 0.5 2.2 2 0 0 2 2 2 1 DAK2 domain DUF1769 PF08588.5 ETS63366.1 - 3.9e-20 71.5 0.7 8.8e-20 70.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Mpv17_PMP22 PF04117.7 ETS63367.1 - 5e-11 42.0 4.1 1.6e-09 37.2 1.6 2.3 1 1 1 2 2 2 2 Mpv17 / PMP22 family POR PF01558.13 ETS63367.1 - 0.02 14.8 0.4 0.7 9.7 0.1 2.8 1 1 1 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase WD40 PF00400.27 ETS63368.1 - 4.5e-36 121.4 0.4 1.6e-07 30.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 ETS63368.1 - 8.4e-31 105.5 1.4 1.8e-30 104.4 1.0 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.3 ETS63368.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PaaX_C PF08223.6 ETS63368.1 - 0.023 14.4 0.3 2.9 7.5 0.0 2.5 2 1 0 2 2 2 0 PaaX-like protein C-terminal domain DUF1631 PF07793.6 ETS63368.1 - 0.1 10.6 1.3 0.19 9.8 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) eIF2A PF08662.6 ETS63368.1 - 0.12 12.0 0.0 1.8 8.2 0.0 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Fungal_trans PF04082.13 ETS63369.1 - 1.7e-30 105.7 0.5 4.5e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63369.1 - 1.1e-11 44.4 8.8 2e-11 43.5 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID-18kDa PF02269.11 ETS63370.1 - 1.1e-28 98.8 0.7 4.9e-28 96.7 0.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit ADH_zinc_N PF00107.21 ETS63371.1 - 3.9e-11 42.6 0.4 2.1e-10 40.2 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63371.1 - 0.0001 23.1 0.0 0.00025 21.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS63371.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Aminotran_4 PF01063.14 ETS63372.1 - 7.9e-21 74.5 0.0 2.2e-20 73.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class IV MFS_1 PF07690.11 ETS63373.1 - 1.6e-29 102.7 38.9 1.6e-29 102.7 27.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF872 PF05915.7 ETS63373.1 - 1.4 8.7 5.6 2.7 7.8 1.2 2.9 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Amidase PF01425.16 ETS63374.1 - 7.5e-81 272.2 0.0 2.8e-79 267.0 0.0 2.0 1 1 0 1 1 1 1 Amidase EutA PF06277.6 ETS63374.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA UDPG_MGDP_dh_N PF03721.9 ETS63375.1 - 1.2e-58 197.5 0.2 9.4e-57 191.3 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 ETS63375.1 - 6e-33 113.1 0.3 5.3e-32 110.1 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 ETS63375.1 - 5.1e-31 106.7 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 ETS63375.1 - 0.013 15.2 0.2 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Metallophos PF00149.23 ETS63376.1 - 9.1e-10 38.2 0.0 5.8e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SpoIIE PF07228.7 ETS63377.1 - 2.9e-14 53.2 0.0 4.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 ETS63377.1 - 0.00017 21.0 0.1 0.00036 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 ETS63377.1 - 0.00041 19.8 0.0 0.043 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C DUF1770 PF08589.5 ETS63378.1 - 7.8e-10 39.2 0.4 1.1e-09 38.7 0.3 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Acyl-CoA_dh_1 PF00441.19 ETS63379.1 - 2.6e-15 56.8 4.5 4.1e-15 56.1 0.1 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS63379.1 - 3.2e-08 32.9 0.1 9.1e-08 31.5 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS63379.1 - 0.0026 18.3 0.1 0.18 12.3 0.0 3.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS63379.1 - 0.023 14.9 1.9 0.072 13.3 0.0 2.5 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain FMN_dh PF01070.13 ETS63380.1 - 1.6e-117 392.3 0.1 2.1e-117 391.9 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS63380.1 - 1.9e-17 62.7 0.0 4.1e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS63380.1 - 2.1e-05 23.6 0.0 3.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS63380.1 - 0.00082 18.3 0.2 0.0033 16.3 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 ETS63380.1 - 0.0088 15.3 0.0 5.6 6.1 0.0 2.8 4 0 0 4 4 4 2 Histidine biosynthesis protein Peripla_BP_4 PF13407.1 ETS63380.1 - 0.014 14.7 0.0 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein domain A_deaminase_N PF08451.6 ETS63380.1 - 0.048 13.6 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Usp PF00582.21 ETS63382.1 - 1.5e-16 60.8 2.0 2.5e-16 60.1 1.4 1.4 1 0 0 1 1 1 1 Universal stress protein family Polysacc_deac_1 PF01522.16 ETS63382.1 - 1.2e-13 50.7 0.0 2.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase GFA PF04828.9 ETS63382.1 - 1.6e-08 34.3 0.8 2.1e-07 30.7 0.6 2.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mss4 PF04421.8 ETS63383.1 - 4.7e-09 35.9 0.0 4.3e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 Mss4 protein Acetyltransf_1 PF00583.19 ETS63383.1 - 4e-08 33.1 0.1 1.1e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS63383.1 - 3.5e-06 27.0 0.0 6.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS63383.1 - 0.007 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS63383.1 - 0.0075 16.0 0.0 0.055 13.2 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein U79_P34 PF03064.11 ETS63383.1 - 0.048 13.1 11.8 0.084 12.3 8.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Acetyltransf_CG PF14542.1 ETS63383.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NARP1 PF12569.3 ETS63383.1 - 0.32 9.6 13.7 0.66 8.6 9.5 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 ETS63383.1 - 4.9 6.5 17.4 7.7 5.8 12.1 1.2 1 0 0 1 1 1 0 DDRGK domain SR-25 PF10500.4 ETS63383.1 - 7 6.0 37.3 0.069 12.6 9.9 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2992 PF11208.3 ETS63383.1 - 7.2 6.5 19.1 13 5.7 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Cellulase PF00150.13 ETS63385.1 - 3.1e-13 49.5 0.0 5.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_5 PF12695.2 ETS63386.1 - 6.2e-14 51.9 0.1 1e-13 51.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS63386.1 - 1.9e-10 40.6 0.8 3e-10 40.0 0.5 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS63386.1 - 2.7e-09 37.2 1.6 3.2e-09 37.0 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS63386.1 - 0.00041 20.1 0.1 0.00088 19.0 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF900 PF05990.7 ETS63386.1 - 0.0019 17.5 0.0 0.64 9.2 0.0 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) COesterase PF00135.23 ETS63386.1 - 0.0035 16.1 0.0 0.0057 15.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS63386.1 - 0.046 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2305 PF10230.4 ETS63386.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Trypsin_2 PF13365.1 ETS63387.1 - 0.024 14.5 0.4 0.055 13.4 0.1 1.8 2 0 0 2 2 2 0 Trypsin-like peptidase domain Abhydrolase_2 PF02230.11 ETS63388.1 - 3.6e-56 190.0 0.0 4.2e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETS63388.1 - 7e-15 55.0 0.1 9.6e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS63388.1 - 3.7e-10 40.0 0.6 9.5e-10 38.7 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS63388.1 - 0.00013 21.2 0.2 0.015 14.5 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 ETS63388.1 - 0.0013 18.1 0.0 0.011 15.1 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 ETS63388.1 - 0.0016 17.8 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 ETS63388.1 - 0.0016 18.0 0.2 0.034 13.7 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 ETS63388.1 - 0.002 17.4 0.1 0.27 10.4 0.0 2.2 1 1 1 2 2 2 1 Esterase PHB depolymerase DLH PF01738.13 ETS63388.1 - 0.0036 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 ETS63388.1 - 0.0065 15.0 0.0 0.012 14.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 ETS63388.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 ETS63388.1 - 0.016 14.9 0.0 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 Cutinase Lipase_3 PF01764.20 ETS63388.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.11 ETS63388.1 - 0.072 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region ADH_zinc_N PF00107.21 ETS63389.1 - 1.2e-27 96.0 0.1 2e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS63389.1 - 5.3e-11 42.2 0.0 2.3e-09 37.0 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS63389.1 - 8.6e-11 42.8 0.1 2.5e-10 41.3 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF2493 PF10686.4 ETS63389.1 - 0.62 9.6 2.8 3 7.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2493) PAF-AH_p_II PF03403.8 ETS63392.1 - 1.7e-43 148.3 0.0 7.5e-41 139.6 0.0 3.9 3 1 0 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 ETS63392.1 - 3.4e-12 46.3 0.0 9.5e-11 41.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS63392.1 - 5.3e-07 29.7 1.6 7.3e-06 26.0 1.1 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS63392.1 - 9.9e-05 22.1 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 ETS63392.1 - 0.0021 17.0 0.0 0.023 13.6 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 ETS63392.1 - 0.028 13.2 0.0 0.077 11.7 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase DNA_pol_viral_N PF00242.12 ETS63392.1 - 1.8 7.5 10.0 4.5 6.2 7.0 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF883 PF05957.8 ETS63393.1 - 3e-07 30.7 90.5 0.045 14.1 1.0 10.4 1 1 8 11 11 11 7 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 ETS63393.1 - 5e-07 29.4 33.5 0.0019 17.7 0.4 5.0 1 1 3 4 4 4 3 Apolipoprotein A1/A4/E domain ApoO PF09769.4 ETS63393.1 - 0.13 11.9 0.1 0.13 11.9 0.1 5.4 4 3 0 5 5 5 0 Apolipoprotein O Prominin PF05478.6 ETS63393.1 - 0.94 6.9 6.7 1.7 6.0 0.7 2.2 2 0 0 2 2 2 0 Prominin Acetyltransf_3 PF13302.1 ETS63394.1 - 1.4e-23 83.6 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS63394.1 - 6.1e-06 26.1 0.2 0.00021 21.2 0.3 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS63394.1 - 0.0044 17.0 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family VCX_VCY PF15231.1 ETS63394.1 - 0.01 16.2 0.5 3.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Variable charge X/Y family FR47 PF08445.5 ETS63394.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein zf-C2H2 PF00096.21 ETS63395.1 - 1.8e-31 106.5 68.3 0.00034 20.7 0.1 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS63395.1 - 3.5e-23 80.1 72.7 0.0018 18.4 0.4 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS63395.1 - 9.4e-14 50.9 51.4 3.3e-07 30.2 0.1 11.2 13 1 0 13 13 13 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETS63395.1 - 0.38 10.9 29.9 15 5.8 0.2 8.4 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS63395.1 - 1.6 9.0 20.4 4 7.7 0.0 7.9 9 0 0 9 9 9 0 Zinc-finger of C2H2 type CHORD PF04968.7 ETS63395.1 - 3.4 7.9 33.0 17 5.7 0.8 7.4 6 1 1 7 7 7 0 CHORD zf-AN1 PF01428.11 ETS63395.1 - 5.2 7.0 10.3 1.2 9.0 2.3 3.5 3 0 0 3 3 3 0 AN1-like Zinc finger zf-SNAP50_C PF12251.3 ETS63396.1 - 1.4e-12 47.4 0.0 3.9e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal GTP_EFTU PF00009.22 ETS63397.1 - 1e-58 197.9 0.2 1.5e-58 197.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS63397.1 - 4.1e-29 100.6 0.0 1e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS63397.1 - 6.4e-17 61.4 3.1 1.8e-16 59.9 2.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ETS63397.1 - 3.1e-05 23.5 0.6 7e-05 22.3 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 ETS63397.1 - 5.3e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 ETS63397.1 - 0.049 13.0 0.8 0.099 12.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 ETS63397.1 - 0.059 12.8 0.3 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 ETS63397.1 - 0.092 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Dus PF01207.12 ETS63398.1 - 1.3e-45 155.5 0.0 3.5e-45 154.1 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 ETS63398.1 - 0.00013 21.0 0.0 0.00025 20.1 0.0 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 ETS63398.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Membr_traf_MHD PF10540.4 ETS63398.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain CHCH PF06747.8 ETS63399.1 - 2.8e-06 27.0 1.1 3.6e-06 26.7 0.7 1.1 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 ETS63399.1 - 0.0007 19.3 0.8 0.00093 18.9 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HTH_5 PF01022.15 ETS63399.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Sec61_beta PF03911.11 ETS63400.1 - 8.5e-18 63.8 1.4 1.1e-17 63.5 0.9 1.1 1 0 0 1 1 1 1 Sec61beta family HEAT_2 PF13646.1 ETS63400.1 - 0.095 12.9 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 HEAT repeats Fasciclin PF02469.17 ETS63402.1 - 8.5e-24 83.9 4.1 1.6e-16 60.4 0.2 2.3 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.20 ETS63403.1 - 1e-05 24.8 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 ETS63403.1 - 3.9e-05 22.7 0.0 0.00026 20.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS63403.1 - 6.4e-05 22.7 0.1 0.0063 16.2 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 ETS63403.1 - 0.00087 18.6 0.1 0.051 12.9 0.1 2.4 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 ETS63403.1 - 0.018 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase 4HBT PF03061.17 ETS63404.1 - 0.00093 19.2 0.2 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Apc5 PF12862.2 ETS63405.1 - 1.2e-12 47.4 2.3 1.1e-11 44.3 0.1 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 DUF3730 PF12530.3 ETS63405.1 - 4.5e-08 33.3 7.3 6.6e-08 32.7 2.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) TPR_2 PF07719.12 ETS63405.1 - 0.019 14.8 0.5 6.5 6.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS63405.1 - 0.031 14.2 12.3 0.07 13.0 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS63405.1 - 0.36 10.7 5.1 2.5 8.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 ETS63405.1 - 8.5 6.9 6.9 60 4.3 0.1 4.2 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Arfaptin PF06456.8 ETS63406.1 - 0.011 15.1 11.1 0.017 14.4 7.7 1.2 1 0 0 1 1 1 0 Arfaptin-like domain Prominin PF05478.6 ETS63406.1 - 0.056 10.9 8.9 0.099 10.1 6.2 1.3 1 0 0 1 1 1 0 Prominin Sec7 PF01369.15 ETS63407.1 - 1.5e-39 135.6 0.1 2.5e-39 134.9 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 ETS63407.1 - 1.6e-13 50.8 0.0 3.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETS63407.1 - 1.5e-10 41.1 0.0 3.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 ETS63407.1 - 0.0033 17.4 0.7 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Herpes_LMP1 PF05297.6 ETS63407.1 - 3.2 6.5 9.2 6.9 5.4 6.4 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) adh_short PF00106.20 ETS63408.1 - 3.9e-64 215.5 9.1 9.8e-33 113.4 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS63408.1 - 1.7e-33 115.7 4.3 8.6e-17 61.3 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 ETS63408.1 - 3.5e-31 107.1 0.0 6.5e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 ETS63408.1 - 1.4e-07 31.3 0.0 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 ETS63408.1 - 6.6e-05 22.0 0.1 0.016 14.3 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 ETS63408.1 - 0.015 14.9 6.6 0.36 10.4 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 ETS63408.1 - 0.021 14.6 0.8 0.77 9.5 0.0 2.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF543 PF04418.7 ETS63408.1 - 0.044 13.7 4.4 4.3 7.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Nro1 PF12753.2 ETS63408.1 - 0.4 9.5 1.4 0.66 8.8 1.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Cation_efflux PF01545.16 ETS63409.1 - 3.9e-49 167.2 1.0 5.3e-49 166.8 0.7 1.2 1 0 0 1 1 1 1 Cation efflux family PH PF00169.24 ETS63410.1 - 2.6e-37 127.1 0.0 1.6e-19 69.9 0.6 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 ETS63410.1 - 9.7e-20 70.8 9.0 2.8e-09 37.1 3.1 4.2 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 ETS63410.1 - 9.6e-18 63.9 5.2 6.9e-09 35.5 1.0 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 ETS63410.1 - 1.2e-09 38.1 3.9 6.2e-07 29.3 1.0 2.6 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 ETS63410.1 - 0.00014 21.9 0.6 0.088 12.9 0.6 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.2 ETS63410.1 - 0.0009 19.1 1.2 2.8 7.8 0.0 3.2 3 0 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_7 PF15408.1 ETS63410.1 - 0.019 14.8 0.1 0.049 13.5 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.1 ETS63410.1 - 0.023 14.2 5.4 3.6 7.0 0.0 3.6 3 1 0 4 4 4 0 Pleckstrin homology domain ESSS PF10183.4 ETS63411.1 - 8.2e-26 90.4 0.8 1.5e-25 89.6 0.5 1.4 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COesterase PF00135.23 ETS63412.1 - 2.5e-74 250.9 0.1 3.4e-74 250.4 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS63412.1 - 2.5e-11 43.5 0.6 1.2e-10 41.3 0.2 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS63412.1 - 3.1e-05 23.3 0.4 7.2e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS63412.1 - 0.0013 18.4 0.4 0.0026 17.5 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3674 PF12426.3 ETS63412.1 - 0.25 10.7 0.6 0.48 9.8 0.4 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase zf-AN1 PF01428.11 ETS63413.1 - 1.3e-18 66.6 29.0 3.5e-10 39.5 4.4 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 ETS63413.1 - 0.042 14.0 17.4 0.21 11.8 2.4 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-HIT PF04438.11 ETS63413.1 - 7.1 6.3 16.5 0.53 9.9 1.6 3.4 3 0 0 3 3 3 0 HIT zinc finger 2OG-FeII_Oxy_2 PF13532.1 ETS63414.1 - 3.1e-27 95.6 0.0 5.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETS63414.1 - 1.2e-08 35.0 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1556 PF07590.6 ETS63414.1 - 5.7 7.2 8.4 1.1 9.5 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1556) PK PF00224.16 ETS63415.1 - 3.5e-160 532.3 5.6 4.3e-160 532.0 3.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 ETS63415.1 - 8.8e-31 105.8 0.0 2.3e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 ETS63415.1 - 0.00029 19.7 0.4 0.001 18.0 0.2 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 ETS63415.1 - 0.0073 15.2 0.2 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Phage_Gp15 PF06854.6 ETS63415.1 - 0.05 13.1 0.1 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Gp15 protein Endonuc-PvuII PF09225.5 ETS63415.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII ELO PF01151.13 ETS63416.1 - 1.6e-63 214.3 8.7 1.9e-63 214.0 6.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family LssY_C PF14067.1 ETS63417.1 - 0.042 12.8 0.5 1.3 7.9 0.3 2.3 2 0 0 2 2 2 0 LssY C-terminus SNAP PF14938.1 ETS63418.1 - 6.1e-98 327.4 16.0 6.8e-98 327.2 11.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 ETS63418.1 - 4.1e-06 26.3 18.7 0.048 13.2 3.7 4.4 1 1 3 4 4 4 3 TPR repeat TPR_12 PF13424.1 ETS63418.1 - 0.00061 19.6 16.7 0.035 14.0 0.6 4.4 1 1 4 5 5 5 4 Tetratricopeptide repeat Spatacsin_C PF14649.1 ETS63418.1 - 0.0026 16.6 4.1 0.018 13.9 2.8 2.0 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_7 PF13176.1 ETS63418.1 - 0.18 11.7 13.1 58 3.8 0.2 5.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS63418.1 - 1 9.0 17.7 11 5.8 1.2 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS63418.1 - 1.8 9.1 18.4 3.7 8.2 0.2 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 ETS63420.1 - 8.1e-07 28.9 0.1 3.8e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 ETS63420.1 - 5.2e-06 26.9 0.0 0.00011 22.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS63420.1 - 6.2e-05 23.0 0.1 0.00032 20.8 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS63420.1 - 0.0016 18.1 0.1 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein GNAT_acetyltr_2 PF13718.1 ETS63420.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_10 PF13673.1 ETS63420.1 - 0.083 13.0 0.0 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CAP_GLY PF01302.20 ETS63421.1 - 1e-26 92.3 1.2 1.6e-26 91.8 0.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 ETS63421.1 - 1.5e-13 50.8 0.0 8.7e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain RRM_1 PF00076.17 ETS63422.1 - 1e-39 134.0 0.1 1e-20 73.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS63422.1 - 4.4e-29 100.2 0.0 4.6e-15 55.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS63422.1 - 2.1e-22 78.6 0.0 1.3e-08 34.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 ETS63422.1 - 1.5e-17 63.5 0.2 3.4e-17 62.4 0.2 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 ETS63422.1 - 0.00018 21.3 0.1 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 ETS63422.1 - 0.075 12.8 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TSP_3 PF02412.13 ETS63422.1 - 3.3 7.2 5.2 0.59 9.6 0.1 2.2 2 0 0 2 2 2 0 Thrombospondin type 3 repeat WD40 PF00400.27 ETS63423.1 - 5.8e-09 35.5 15.2 0.0016 18.2 0.0 7.2 8 0 0 8 8 8 2 WD domain, G-beta repeat eIF2A PF08662.6 ETS63423.1 - 6.3e-05 22.7 0.0 1.2 8.7 0.0 4.3 5 0 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.16 ETS63423.1 - 0.072 11.6 0.3 29 3.0 0.0 3.7 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lactonase PF10282.4 ETS63423.1 - 0.23 10.4 0.0 6.7 5.6 0.0 2.8 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller IKI3 PF04762.7 ETS63423.1 - 0.32 8.7 0.3 37 1.9 0.0 3.4 4 0 0 4 4 4 0 IKI3 family DUF2348 PF09807.4 ETS63424.1 - 9.8e-09 34.6 0.1 5.9e-08 32.1 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2348) SIP PF04954.8 ETS63424.1 - 0.07 13.5 0.2 2 8.8 0.0 2.4 2 0 0 2 2 2 0 Siderophore-interacting protein Glycos_transf_1 PF00534.15 ETS63425.1 - 1e-30 106.3 0.0 3.8e-29 101.3 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 ETS63425.1 - 1e-15 58.2 0.1 3.7e-15 56.4 0.1 2.0 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 ETS63425.1 - 2.6e-13 50.0 0.0 6.6e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 ETS63425.1 - 5.3e-12 46.0 0.0 1.5e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETS63425.1 - 0.0048 17.1 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 FCH PF00611.18 ETS63426.1 - 4.9e-18 65.1 1.5 9.1e-18 64.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 ETS63426.1 - 1.7e-12 46.5 0.1 3e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS63426.1 - 4.8e-11 42.0 0.0 8.9e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS63426.1 - 8.2e-09 34.8 0.0 2.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain CorA PF01544.13 ETS63427.1 - 6.2e-14 51.7 5.8 1.6e-07 30.6 0.1 3.9 4 1 0 4 4 4 3 CorA-like Mg2+ transporter protein Yip1 PF04893.12 ETS63427.1 - 0.15 11.5 0.5 0.25 10.8 0.3 1.2 1 0 0 1 1 1 0 Yip1 domain COX7C PF02935.11 ETS63428.1 - 9.7e-11 41.3 1.9 1.4e-10 40.7 1.3 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Brix PF04427.13 ETS63429.1 - 4.5e-46 156.9 0.0 6.2e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.27 ETS63430.1 - 8e-25 85.7 8.8 4.9e-09 35.7 0.7 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 ETS63430.1 - 7.7e-06 25.5 0.6 0.0007 19.1 0.1 2.4 2 0 0 2 2 2 1 PQQ-like domain eIF2A PF08662.6 ETS63430.1 - 0.0014 18.3 0.2 2.1 8.0 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 ETS63430.1 - 0.018 15.2 2.2 7.1 7.0 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain Apc4_WD40 PF12894.2 ETS63430.1 - 0.031 13.7 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 ETS63430.1 - 0.04 12.2 0.2 4.5 5.4 0.0 3.0 3 0 0 3 3 3 0 Cytochrome D1 heme domain Neuropep_like PF15161.1 ETS63430.1 - 0.053 13.0 0.1 0.19 11.2 0.1 1.9 1 0 0 1 1 1 0 Neuropeptide-like CRT10 PF08728.5 ETS63430.1 - 0.14 10.1 0.0 0.22 9.4 0.0 1.2 1 0 0 1 1 1 0 CRT10 COesterase PF00135.23 ETS63431.1 - 1.5e-108 363.8 0.1 5.4e-108 362.0 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS63431.1 - 1.7e-05 24.5 2.3 0.00011 21.8 0.7 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Zn_clus PF00172.13 ETS63432.1 - 0.015 15.1 5.7 0.029 14.2 3.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.4 ETS63433.1 - 0.01 14.8 5.6 0.051 12.5 2.8 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-P PF13096.1 ETS63433.1 - 0.016 14.5 0.0 3.1 7.0 0.0 2.5 3 0 0 3 3 3 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Mnd1 PF03962.10 ETS63433.1 - 2.2 7.9 8.6 0.64 9.6 3.4 1.8 2 0 0 2 2 2 0 Mnd1 family DUF947 PF06102.7 ETS63434.1 - 5.7e-48 162.9 19.5 5.7e-48 162.9 13.5 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF947) BING4CT PF08149.6 ETS63435.1 - 4e-33 112.7 0.0 5.3e-32 109.1 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 ETS63435.1 - 1.2e-09 37.6 0.0 1.3e-05 24.8 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 ETS63435.1 - 0.00015 20.6 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region DUF2046 PF09755.4 ETS63435.1 - 0.013 14.3 3.0 0.021 13.7 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) GFO_IDH_MocA PF01408.17 ETS63436.1 - 9.1e-13 48.7 0.0 2.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 ETS63436.1 - 0.055 12.4 0.1 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase CoA_binding_2 PF13380.1 ETS63436.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Syja_N PF02383.13 ETS63437.1 - 2.6e-92 309.0 0.1 3.6e-92 308.5 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain JAB PF01398.16 ETS63438.1 - 9e-21 73.7 0.1 2.1e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETS63438.1 - 2.5e-13 50.1 0.4 6.7e-13 48.7 0.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function SH2_2 PF14633.1 ETS63439.1 - 2.3e-69 232.8 0.1 7.2e-69 231.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 ETS63439.1 - 4e-26 91.3 0.6 4e-26 91.3 0.4 2.9 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 ETS63439.1 - 4.4e-22 78.1 0.0 8.7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 ETS63439.1 - 5.9e-22 77.8 0.0 1.5e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 ETS63439.1 - 3e-20 72.1 26.7 3e-20 72.1 18.5 4.7 3 1 1 4 4 4 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 ETS63439.1 - 3.3e-09 36.7 0.2 8.9e-09 35.3 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.2 ETS63439.1 - 0.0077 16.1 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.19 ETS63439.1 - 0.01 15.6 0.0 0.034 13.9 0.0 2.0 1 0 0 1 1 1 0 SH2 domain MFS_1 PF07690.11 ETS63441.1 - 1.1e-24 86.8 18.5 5.9e-20 71.2 4.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 ETS63441.1 - 1.3e-14 54.1 2.3 1.3e-14 54.1 1.6 2.9 3 0 0 3 3 3 1 Nodulin-like DUF543 PF04418.7 ETS63441.1 - 0.075 12.9 0.5 5.5 7.0 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF3392 PF11872.3 ETS63441.1 - 0.94 9.4 4.4 3.6 7.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) Rad21_Rec8_N PF04825.8 ETS63442.1 - 4.4e-28 97.4 0.0 7.2e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 ETS63442.1 - 8.1e-09 34.5 0.5 8.1e-09 34.5 0.4 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 ETS63442.1 - 0.029 13.9 0.6 0.043 13.4 0.0 1.5 2 0 0 2 2 2 0 ScpA/B protein Autophagy_N PF03986.8 ETS63444.1 - 7.7e-47 158.7 0.0 1.7e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 ETS63444.1 - 9.8e-29 99.3 0.0 2e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 ETS63444.1 - 1.6e-13 49.4 0.5 3.1e-13 48.5 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal BLUF PF04940.7 ETS63445.1 - 6.1e-32 109.2 0.0 9.5e-32 108.5 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD DUF1053 PF06327.9 ETS63445.1 - 0.37 11.1 2.5 3.5 8.0 0.1 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) NUC153 PF08159.7 ETS63446.1 - 1.4e-12 46.9 12.3 4.1e-10 39.0 0.3 3.7 3 0 0 3 3 3 3 NUC153 domain LSM PF01423.17 ETS63447.1 - 9.7e-21 73.1 0.1 1.1e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain Bud13 PF09736.4 ETS63448.1 - 1.8e-42 145.0 0.8 1.8e-42 145.0 0.5 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Zn_clus PF00172.13 ETS63451.1 - 9.6e-06 25.4 4.2 1.9e-05 24.4 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Grp1_Fun34_YaaH PF01184.14 ETS63452.1 - 5.8e-82 274.0 17.4 7.3e-82 273.7 12.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 ETS63452.1 - 1.3 7.9 5.6 1.7 7.5 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Transglycosylas PF06737.9 ETS63452.1 - 7.2 6.9 7.0 8.2 6.8 0.3 2.8 3 0 0 3 3 3 0 Transglycosylase-like domain Ribosomal_L31e PF01198.14 ETS63454.1 - 1.5e-35 120.7 2.4 2.3e-35 120.0 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e JAB PF01398.16 ETS63455.1 - 1.2e-05 24.9 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4203 PF13886.1 ETS63457.1 - 3.4e-27 95.2 21.2 4.5e-27 94.8 14.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Pro_CA PF00484.14 ETS63458.1 - 7.1e-40 136.5 0.2 1.1e-39 135.9 0.2 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_6 PF12697.2 ETS63458.1 - 0.006 16.4 2.7 0.32 10.8 0.7 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63458.1 - 0.11 12.0 2.0 0.65 9.5 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold p450 PF00067.17 ETS63459.1 - 1.3e-54 185.5 0.0 2.4e-54 184.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 ETS63461.1 - 3.5e-63 212.7 2.1 3.5e-63 212.7 1.4 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS63461.1 - 4.4e-34 117.5 4.2 4.4e-34 117.5 2.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS63461.1 - 2.7e-29 103.1 0.1 1.3e-27 97.6 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS63461.1 - 6e-18 64.0 5.1 7.6e-18 63.7 0.1 3.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 ETS63461.1 - 7.7e-18 64.2 0.0 2.7e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS63461.1 - 4.2e-10 40.0 0.1 1e-09 38.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS63461.1 - 0.0032 17.0 0.1 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HSP9_HSP12 PF04119.7 ETS63462.1 - 3.4e-21 75.0 7.3 8.5e-21 73.8 3.3 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.1 ETS63462.1 - 0.0078 16.3 9.6 0.022 14.8 2.9 2.3 1 1 1 2 2 2 2 MT0933-like antitoxin protein Sugar_tr PF00083.19 ETS63463.1 - 7.5e-24 84.1 19.0 1.1e-22 80.2 4.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS63463.1 - 4.2e-21 75.0 57.4 7.7e-15 54.4 20.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS63463.1 - 0.013 15.3 0.4 0.013 15.3 0.3 2.2 2 0 0 2 2 2 0 MFS_1 like family Mito_carr PF00153.22 ETS63464.1 - 1.6e-63 210.4 4.0 1.1e-21 76.3 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein MSC PF09402.5 ETS63465.1 - 5.6e-85 284.9 0.0 7.6e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 ETS63465.1 - 1.2e-13 50.3 0.0 3.7e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 HeH/LEM domain FAD_binding_3 PF01494.14 ETS63467.1 - 6e-14 51.8 0.2 2.1e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 ETS63467.1 - 1.2e-05 25.6 0.0 0.28 11.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS63467.1 - 0.0025 16.7 0.0 0.0062 15.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS63467.1 - 0.0026 17.8 0.1 0.0059 16.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PAT1 PF09770.4 ETS63468.1 - 5.5 5.1 11.5 6.7 4.8 8.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spc24 PF08286.6 ETS63470.1 - 2.7e-10 39.9 17.8 2.4e-06 27.2 5.1 3.2 2 1 1 3 3 3 2 Spc24 subunit of Ndc80 Filament PF00038.16 ETS63470.1 - 0.0012 18.3 4.9 0.0012 18.3 3.4 1.9 1 1 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.6 ETS63470.1 - 0.06 12.0 10.7 0.087 11.4 7.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 ETS63470.1 - 0.13 11.4 13.0 0.2 10.8 9.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sec2p PF06428.6 ETS63470.1 - 0.24 11.2 10.0 0.3 10.9 4.9 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Vps51 PF08700.6 ETS63470.1 - 0.66 9.8 8.1 6.1 6.7 0.9 3.2 1 1 2 3 3 3 0 Vps51/Vps67 V_ATPase_I PF01496.14 ETS63470.1 - 0.79 7.4 8.6 0.85 7.3 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 ETS63470.1 - 0.87 7.6 8.3 1.5 6.9 5.8 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like Atg14 PF10186.4 ETS63470.1 - 1 8.2 8.1 1.3 7.9 5.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RasGAP_C PF03836.10 ETS63470.1 - 1 9.0 10.5 2.1 8.0 1.1 2.3 1 1 0 1 1 1 0 RasGAP C-terminus TMF_DNA_bd PF12329.3 ETS63470.1 - 1.3 8.8 17.3 0.16 11.8 4.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MutS_III PF05192.13 ETS63470.1 - 2.3 7.9 9.4 6.8 6.4 5.8 1.9 1 1 1 2 2 2 0 MutS domain III DUF342 PF03961.8 ETS63470.1 - 2.5 6.4 8.1 4.4 5.6 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DivIVA PF05103.8 ETS63470.1 - 6.7 6.7 15.5 0.82 9.7 4.3 2.3 1 1 1 2 2 2 0 DivIVA protein ACCA PF03255.9 ETS63470.1 - 8.3 5.9 7.6 1.9 7.9 1.2 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMCO5 PF14992.1 ETS63470.1 - 8.9 5.3 18.5 0.31 10.1 5.5 2.1 1 1 1 2 2 2 0 TMCO5 family FUSC PF04632.7 ETS63470.1 - 9.6 4.4 7.6 11 4.3 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vac_ImportDeg PF09783.4 ETS63471.1 - 3.5e-57 192.7 0.0 1.5e-51 174.4 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein DJ-1_PfpI_N PF13587.1 ETS63471.1 - 0.011 15.2 0.0 0.037 13.5 0.0 1.9 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family Gpi1 PF05024.10 ETS63472.1 - 2.1e-39 135.1 5.1 3.5e-39 134.4 3.5 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) AA_kinase PF00696.23 ETS63473.1 - 8.2e-40 136.8 0.9 1.1e-39 136.4 0.6 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 ETS63473.1 - 7.7e-10 38.3 0.7 8.7e-05 22.1 0.0 2.7 3 0 0 3 3 3 2 PUA domain AAA PF00004.24 ETS63474.1 - 3.2e-17 62.9 0.0 1.2e-16 61.0 0.0 2.0 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 ETS63474.1 - 5.2e-14 52.2 0.0 2.3e-13 50.1 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 ETS63474.1 - 5.5e-09 35.2 0.1 6e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 ETS63474.1 - 6.7e-09 35.6 0.0 1.7e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 ETS63474.1 - 3.7e-08 33.5 0.6 0.00095 19.3 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.1 ETS63474.1 - 1.5e-05 24.9 0.0 8.4e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS63474.1 - 2.1e-05 24.1 0.1 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 ETS63474.1 - 2.5e-05 23.4 0.0 5.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETS63474.1 - 3.2e-05 24.0 0.0 0.00079 19.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 ETS63474.1 - 4.6e-05 23.1 0.0 0.00011 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS63474.1 - 0.00059 19.5 0.1 0.0023 17.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS63474.1 - 0.00079 18.6 0.1 0.025 13.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 ETS63474.1 - 0.0011 18.5 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS63474.1 - 0.0043 16.6 0.0 0.029 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETS63474.1 - 0.0083 16.1 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETS63474.1 - 0.0083 15.5 0.1 0.027 13.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ETS63474.1 - 0.0098 15.3 0.1 0.2 11.0 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_3 PF07726.6 ETS63474.1 - 0.014 14.9 0.2 0.057 13.0 0.0 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETS63474.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 ETS63474.1 - 0.02 14.4 0.2 0.27 10.7 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 ETS63474.1 - 0.023 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETS63474.1 - 0.029 13.3 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 ETS63474.1 - 0.03 15.1 0.0 0.077 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS63474.1 - 0.03 13.7 0.2 0.27 10.6 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family Parvo_NS1 PF01057.12 ETS63474.1 - 0.038 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_2 PF07724.9 ETS63474.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 3 0 0 3 3 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 ETS63474.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 ETS63474.1 - 0.088 12.6 0.0 0.28 10.9 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 ETS63474.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 ETS63474.1 - 0.13 11.0 0.0 2.1 7.0 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_23 PF13476.1 ETS63474.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CAF1A PF12253.3 ETS63475.1 - 1e-22 80.0 8.1 1e-22 80.0 5.6 2.6 1 1 1 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 ETS63475.1 - 0.00024 20.5 26.3 0.00024 20.5 18.2 3.8 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal WD40 PF00400.27 ETS63476.1 - 2.9e-60 198.1 16.4 3.1e-11 42.6 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETS63476.1 - 6.4e-08 32.5 0.1 0.0059 16.3 0.0 3.7 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 ETS63476.1 - 0.0022 17.7 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region MgtE PF01769.11 ETS63477.1 - 4.6e-23 81.9 35.2 5.9e-09 36.3 1.3 5.1 3 2 1 4 4 4 3 Divalent cation transporter MFS_1 PF07690.11 ETS63478.1 - 1.4e-18 66.7 63.9 5.1e-11 41.8 19.7 3.6 2 2 1 3 3 3 2 Major Facilitator Superfamily Tetraspannin PF00335.15 ETS63478.1 - 1.7e-05 24.2 4.4 1.7e-05 24.2 3.1 2.3 2 0 0 2 2 2 1 Tetraspanin family MIP PF00230.15 ETS63480.1 - 6.2e-51 173.0 16.8 8.4e-51 172.6 11.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein FMN_bind_2 PF04299.7 ETS63481.1 - 1.5e-43 148.2 0.0 2.3e-43 147.5 0.0 1.3 1 1 0 1 1 1 1 Putative FMN-binding domain DUF1325 PF07039.6 ETS63483.1 - 1.6e-33 115.0 0.0 2.4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain E1-E2_ATPase PF00122.15 ETS63484.1 - 2.6e-46 157.5 0.9 5.7e-46 156.3 0.6 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETS63484.1 - 1.3e-41 143.4 1.8 3.7e-41 141.8 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 ETS63484.1 - 2.5e-29 101.2 0.0 1.6e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 ETS63484.1 - 3.9e-16 59.7 0.0 1.2e-15 58.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS63484.1 - 5.4e-05 22.8 0.7 0.012 15.1 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETS63484.1 - 0.011 15.5 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FMO-like PF00743.14 ETS63487.1 - 1.3e-25 89.6 0.0 2.7e-14 52.2 0.0 3.2 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS63487.1 - 1.4e-11 44.8 0.0 6.3e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS63487.1 - 7.6e-09 35.5 0.1 6.8e-06 25.9 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS63487.1 - 2.4e-08 34.0 0.0 0.0038 17.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS63487.1 - 3.7e-08 33.2 0.4 8.2e-08 32.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS63487.1 - 1.2e-05 24.3 0.0 0.067 12.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS63487.1 - 0.00031 19.7 0.0 0.0011 17.9 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS63487.1 - 0.0026 16.8 0.1 0.013 14.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 ETS63487.1 - 0.0069 16.7 0.1 0.04 14.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS63487.1 - 0.0094 14.4 0.1 0.015 13.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 ETS63487.1 - 0.0095 15.0 0.2 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS63487.1 - 0.019 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 ETS63487.1 - 0.04 12.9 0.2 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Formyl_trans_N PF00551.14 ETS63488.1 - 3.2e-36 124.5 0.0 4.7e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 ETS63488.1 - 1.5e-06 27.5 0.0 3.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 ETS63488.1 - 3.1e-05 23.6 0.0 8.4e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 ACT domain Gtr1_RagA PF04670.7 ETS63489.1 - 2.4e-87 291.9 0.0 3.1e-87 291.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 ETS63489.1 - 1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 ETS63489.1 - 0.00035 20.5 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 ETS63489.1 - 0.00058 19.1 0.0 0.00092 18.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETS63489.1 - 0.0017 18.8 0.0 0.0056 17.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 ETS63489.1 - 0.012 15.0 0.1 0.078 12.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 ETS63489.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 ETS63489.1 - 0.088 11.9 0.1 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 ETS63489.1 - 0.091 12.3 0.0 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Smg4_UPF3 PF03467.10 ETS63490.1 - 8.6e-31 107.2 0.0 1.9e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Smg-4/UPF3 family SYF2 PF08231.7 ETS63491.1 - 1.2e-40 139.1 17.0 2.1e-40 138.3 11.8 1.4 1 0 0 1 1 1 1 SYF2 splicing factor Cellulase PF00150.13 ETS63492.1 - 1.3e-12 47.4 0.3 1.3e-12 47.4 0.2 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Response_reg PF00072.19 ETS63494.1 - 1.9e-21 76.1 0.0 3.7e-15 55.8 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain Ribosomal_S6 PF01250.12 ETS63495.1 - 1e-12 47.6 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DEAD PF00270.24 ETS63496.1 - 3.5e-31 107.9 0.0 6.3e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS63496.1 - 2.6e-24 84.8 0.0 8e-24 83.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4137 PF13593.1 ETS63496.1 - 0.047 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) EF_assoc_1 PF08355.7 ETS63497.1 - 0.00092 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_4 PF12763.2 ETS63497.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Mito_carr PF00153.22 ETS63499.1 - 1e-60 201.4 1.9 6.1e-20 70.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ndc80_HEC PF03801.8 ETS63500.1 - 1.6e-38 131.6 0.0 5.7e-38 129.8 0.0 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family Flag1_repress PF03614.8 ETS63500.1 - 0.021 14.4 0.5 0.044 13.3 0.4 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin DUF2031 PF09592.5 ETS63500.1 - 0.07 12.2 7.1 0.14 11.2 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Lzipper-MIP1 PF14389.1 ETS63500.1 - 0.9 9.6 13.2 0.11 12.6 4.0 3.0 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 ETS63500.1 - 9.3 5.3 37.4 5.2 6.2 6.9 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Cellulase PF00150.13 ETS63501.1 - 4.2e-08 32.7 0.0 9.8e-06 24.9 0.0 2.7 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Utp14 PF04615.8 ETS63502.1 - 1.3 7.1 18.0 1.4 7.0 12.4 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2217 PF10265.4 ETS63502.1 - 4 6.0 14.2 4.9 5.7 9.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Peptidase_S64 PF08192.6 ETS63502.1 - 4.7 5.4 19.5 4.9 5.3 13.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.4 ETS63502.1 - 8.6 4.4 12.5 9.5 4.3 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 ETS63503.1 - 5.4e-17 62.4 4.7 5.4e-17 62.4 3.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63503.1 - 8.3e-10 38.6 0.1 3.3e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS63503.1 - 6.4e-09 35.7 0.9 4.6e-08 32.9 0.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS63503.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold RRM_6 PF14259.1 ETS63505.1 - 2.1e-14 53.2 0.0 3.7e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS63505.1 - 1.1e-12 47.4 0.0 7.2e-11 41.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS63505.1 - 7.9e-12 44.8 0.0 7e-06 25.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS2 PF02187.12 ETS63506.1 - 1.6e-08 34.1 0.0 3.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain adh_short PF00106.20 ETS63507.1 - 8e-29 100.6 0.0 1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS63507.1 - 2.1e-12 47.3 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS63507.1 - 4.5e-12 46.0 0.0 7.9e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS63507.1 - 3.6e-05 23.3 0.0 8.2e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 ETS63507.1 - 6.3e-05 22.2 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 ETS63507.1 - 0.00069 19.6 0.1 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS63507.1 - 0.0015 18.2 0.1 0.003 17.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 ETS63507.1 - 0.0065 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 ETS63507.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS63507.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fasciclin PF02469.17 ETS63508.1 - 4.8e-55 185.0 0.1 9.2e-13 48.3 0.0 6.9 7 1 0 7 7 7 6 Fasciclin domain RINGv PF12906.2 ETS63509.1 - 1.2e-12 47.5 4.4 1.9e-12 46.9 3.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 ETS63509.1 - 0.015 15.1 2.4 0.025 14.4 1.7 1.3 1 0 0 1 1 1 0 Ring finger domain Radical_SAM PF04055.16 ETS63510.1 - 1.1e-15 58.1 0.1 3.4e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 ETS63510.1 - 1.3e-10 41.1 0.0 3.9e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS63510.1 - 0.0089 16.1 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS63510.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein GCV_H PF01597.14 ETS63511.1 - 9.1e-44 148.0 0.1 1.1e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 ETS63511.1 - 3.1e-05 23.4 0.2 5.7e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 ETS63511.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 ETS63511.1 - 0.019 14.6 0.9 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Mito_carr PF00153.22 ETS63514.1 - 7.9e-45 150.5 2.0 3.9e-16 58.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF498 PF04430.9 ETS63515.1 - 3.5e-24 84.4 0.0 8.8e-24 83.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) zf-H2C2_2 PF13465.1 ETS63516.1 - 3e-22 77.7 53.1 6.4e-08 32.5 2.5 8.2 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.21 ETS63516.1 - 7.4e-20 70.0 46.4 1.2e-05 25.3 0.2 9.1 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS63516.1 - 7e-08 32.2 52.5 0.0007 19.7 0.5 9.1 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS63516.1 - 5.9e-07 29.4 12.8 0.00084 19.4 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS63516.1 - 0.058 13.3 0.4 0.058 13.3 0.3 5.3 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 ETS63516.1 - 0.062 13.5 0.5 0.062 13.5 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETS63516.1 - 1.2 9.3 18.2 0.035 14.2 0.7 4.6 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) RNA_polI_A34 PF08208.6 ETS63517.1 - 3e-06 27.0 7.6 0.0011 18.6 1.1 2.5 3 0 0 3 3 3 2 DNA-directed RNA polymerase I subunit RPA34.5 DUF4170 PF13773.1 ETS63517.1 - 0.17 11.8 0.2 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) adh_short PF00106.20 ETS63518.1 - 1.2e-10 41.6 11.4 1.3e-05 25.1 0.6 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS63518.1 - 2.5e-07 30.5 6.5 3.6e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 ETS63518.1 - 0.00073 19.3 2.1 0.44 10.2 1.3 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 2OG-FeII_Oxy_2 PF13532.1 ETS63520.1 - 3.8e-13 49.6 0.0 7.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 ETS63522.1 - 2.2e-23 81.6 0.0 2.1e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 ETS63522.1 - 3.1e-21 73.5 0.0 0.00034 19.9 0.0 6.5 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 ETS63522.1 - 7.1e-17 61.1 0.0 4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS63522.1 - 3.5e-14 52.3 0.1 1.1e-06 28.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.20 ETS63523.1 - 5.4e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 ETS63523.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family SNARE_assoc PF09335.6 ETS63524.1 - 3.6e-16 59.4 9.6 3.6e-16 59.4 6.7 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4149 PF13664.1 ETS63524.1 - 1.7 8.7 10.8 0.26 11.3 1.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Coa1 PF08695.5 ETS63525.1 - 2.1e-27 94.9 0.1 2.9e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 UPF0197 PF05251.7 ETS63525.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) Pkinase PF00069.20 ETS63526.1 - 8.7e-35 120.1 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63526.1 - 2.9e-13 49.4 0.0 4.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_phi PF04931.8 ETS63527.1 - 1.3e-66 224.9 20.1 7.6e-66 222.4 10.1 2.6 2 1 0 2 2 2 1 DNA polymerase phi RskA PF10099.4 ETS63528.1 - 0.028 14.1 0.5 0.048 13.4 0.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PGG PF13962.1 ETS63528.1 - 0.35 10.4 2.6 1.1 8.9 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function NPR2 PF06218.6 ETS63529.1 - 1.1e-99 334.0 0.0 6.2e-45 153.6 0.0 4.2 3 1 1 4 4 4 4 Nitrogen permease regulator 2 Acetyltransf_1 PF00583.19 ETS63529.1 - 7.1e-13 48.4 0.2 1.6e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HhH-GPD PF00730.20 ETS63529.1 - 1.6e-10 41.2 0.0 5.4e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein FR47 PF08445.5 ETS63529.1 - 0.0022 17.7 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein NPR3 PF03666.8 ETS63529.1 - 0.023 13.2 0.7 3.4 6.1 0.0 2.5 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M28 PF04389.12 ETS63530.1 - 1.3e-35 122.7 0.9 1.9e-35 122.2 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M28 Homeobox PF00046.24 ETS63531.1 - 2.6e-12 46.1 1.0 8.1e-12 44.5 0.7 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 ETS63531.1 - 0.0027 17.3 0.0 0.0087 15.7 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Sec63 PF02889.11 ETS63532.1 - 1.9e-82 276.9 0.0 4e-82 275.9 0.0 1.5 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.24 ETS63532.1 - 1.2e-42 145.2 1.1 3.6e-30 104.6 0.1 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ApbA_C PF08546.6 ETS63532.1 - 4.5e-26 91.2 0.4 3.9e-25 88.2 0.0 2.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 ETS63532.1 - 1.2e-20 73.5 0.0 2.9e-19 68.9 0.0 2.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ResIII PF04851.10 ETS63532.1 - 1.4e-11 44.5 0.0 4.4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS63532.1 - 1.5e-06 27.9 0.0 1e-05 25.2 0.0 2.5 3 0 0 3 3 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETS63532.1 - 1.8e-05 24.8 0.1 0.023 14.8 0.0 3.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS63532.1 - 0.00012 21.1 0.0 0.095 11.5 0.0 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 ETS63532.1 - 0.00069 19.0 0.2 0.96 8.8 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_29 PF13555.1 ETS63532.1 - 0.0031 17.0 0.0 0.027 13.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 ETS63532.1 - 0.0078 15.6 0.0 0.48 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain SNF2_N PF00176.18 ETS63532.1 - 0.0095 14.7 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 ETS63532.1 - 0.05 12.8 0.1 11 5.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.9 ETS63532.1 - 0.13 11.9 0.1 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 ETS63532.1 - 1.6 9.0 0.0 9.2 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Synaptobrevin PF00957.16 ETS63533.1 - 1.1e-24 85.8 0.1 1.4e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 ETS63533.1 - 1.1e-21 76.1 0.0 1.7e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain T4SS PF07996.6 ETS63533.1 - 0.029 14.2 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins IstB_IS21_ATP PF08483.6 ETS63533.1 - 0.048 13.3 0.2 0.85 9.3 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Acyl-CoA_dh_2 PF08028.6 ETS63533.1 - 0.062 13.5 0.5 0.1 12.8 0.3 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Lactonase PF10282.4 ETS63536.1 - 1.5e-14 53.8 0.5 4.7e-13 48.9 0.1 2.1 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Tom37_C PF11801.3 ETS63537.1 - 9.3e-07 28.8 0.1 0.022 14.6 0.0 2.8 3 0 0 3 3 3 2 Tom37 C-terminal domain TFIIA PF03153.8 ETS63537.1 - 5.7e-05 23.1 3.8 6.7e-05 22.9 2.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GST_C_2 PF13410.1 ETS63537.1 - 0.00024 20.9 0.0 0.00058 19.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 ETS63537.1 - 0.00049 20.3 0.2 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 ETS63537.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA_Me_trans PF03054.11 ETS63538.1 - 1.9e-106 355.6 0.0 4.4e-106 354.4 0.0 1.5 1 1 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 ETS63538.1 - 0.014 14.3 0.1 0.26 10.1 0.0 2.2 2 0 0 2 2 2 0 NAD synthase PTCB-BRCT PF12738.2 ETS63539.1 - 1.1e-34 118.0 0.0 8.7e-14 51.1 0.0 4.6 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 ETS63539.1 - 8.6e-31 105.9 0.0 3.1e-11 43.2 0.0 5.5 5 0 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain CENP-C_C PF11699.3 ETS63539.1 - 7e-29 99.6 0.0 1.2e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 ETS63539.1 - 0.0066 15.9 0.0 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Cupin domain CLTH PF10607.4 ETS63540.1 - 9.9e-21 73.9 0.0 1.4e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 ETS63540.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 LisH Herpes_capsid PF06112.6 ETS63540.1 - 4.7 7.2 32.9 2.5 8.1 1.7 3.7 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein WD40 PF00400.27 ETS63541.1 - 1.5e-22 78.5 10.8 4.7e-07 29.4 0.5 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 ETS63541.1 - 0.0046 15.1 2.8 0.27 9.3 0.0 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Brix PF04427.13 ETS63542.1 - 1.3e-27 96.7 0.0 3.1e-27 95.4 0.0 1.6 1 1 0 1 1 1 1 Brix domain BUD22 PF09073.5 ETS63542.1 - 0.066 12.2 18.9 0.096 11.7 13.1 1.2 1 0 0 1 1 1 0 BUD22 Peptidase_S28 PF05577.7 ETS63543.1 - 1e-39 136.3 0.0 1.6e-35 122.5 0.0 2.6 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 ETS63543.1 - 0.0032 17.3 1.0 0.016 15.1 0.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ras PF00071.17 ETS63544.1 - 3e-52 176.2 0.0 3.9e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS63544.1 - 5.5e-15 55.9 0.0 8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS63544.1 - 4.5e-06 26.0 0.0 7.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-C3HC4_3 PF13920.1 ETS63545.1 - 0.00088 18.9 7.3 0.0014 18.2 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS63545.1 - 0.053 13.5 11.6 0.082 12.9 8.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS63545.1 - 0.056 13.1 11.1 0.086 12.5 7.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.9 ETS63546.1 - 3.5e-48 164.0 0.7 4.4e-48 163.6 0.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 ETS63546.1 - 2.1e-06 27.6 1.7 3.4e-06 26.9 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS63546.1 - 9.6e-05 21.9 1.1 0.00016 21.2 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS63546.1 - 0.00041 20.1 4.4 0.0017 18.1 3.1 1.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETS63546.1 - 0.011 15.3 0.9 0.017 14.7 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS63546.1 - 0.06 13.2 4.1 0.1 12.4 2.9 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UCH PF00443.24 ETS63547.1 - 2.9e-45 154.5 0.0 4.1e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 ETS63547.1 - 5.9e-25 87.1 7.7 4.9e-19 68.2 1.2 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 ETS63547.1 - 5.8e-19 67.3 1.4 3.7e-09 36.1 0.2 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 ETS63547.1 - 1.6e-18 67.1 0.0 1.2e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 ETS63547.1 - 0.042 13.3 0.2 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Met_10 PF02475.11 ETS63549.1 - 1.1e-51 175.3 0.0 2.7e-45 154.4 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein PIG-L PF02585.12 ETS63550.1 - 4.3e-23 82.2 0.5 6.1e-23 81.7 0.3 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Chorismate_bind PF00425.13 ETS63551.1 - 1e-84 283.8 0.0 1.5e-84 283.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 ETS63551.1 - 1.1e-28 99.9 0.0 3.8e-28 98.2 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region PRP21_like_P PF12230.3 ETS63552.1 - 1.3e-60 204.7 0.8 4.9e-60 202.8 0.3 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 ETS63552.1 - 6.5e-31 105.7 0.7 2.2e-14 52.8 0.1 2.5 2 0 0 2 2 2 2 Surp module AP_endonuc_2 PF01261.19 ETS63554.1 - 1.6e-28 99.5 0.0 2.9e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel WD40 PF00400.27 ETS63556.1 - 5.5e-18 64.0 6.2 2.4e-06 27.2 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Asn_synthase PF00733.16 ETS63557.1 - 1.1e-66 224.9 0.2 2.4e-66 223.8 0.2 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 ETS63557.1 - 1e-37 128.6 0.0 1.6e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETS63557.1 - 5.6e-30 104.0 0.0 1.2e-29 102.9 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 ETS63557.1 - 2.3e-08 33.1 0.0 6.7e-05 21.7 0.0 2.8 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 ETS63557.1 - 4.5e-06 26.0 0.0 9.5e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 ETS63557.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase DUF1776 PF08643.5 ETS63558.1 - 2e-06 27.1 0.0 0.055 12.5 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.20 ETS63558.1 - 0.0026 17.6 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase DEAD PF00270.24 ETS63559.1 - 4.7e-30 104.2 0.0 9.2e-28 96.8 0.0 2.9 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS63559.1 - 2.3e-20 72.2 0.0 5e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 ETS63559.1 - 0.045 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS63559.1 - 0.059 12.1 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 ETS63559.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain BATS PF06968.8 ETS63560.1 - 8.1e-27 92.9 0.0 2e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 ETS63560.1 - 6.5e-15 55.6 0.1 1.4e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Zn_clus PF00172.13 ETS63561.1 - 6e-10 38.8 26.5 4.2e-08 32.9 5.8 2.9 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 ETS63563.1 - 0.013 15.2 1.0 0.098 12.3 0.1 2.5 2 0 0 2 2 2 0 F-box-like Ribosomal_L10 PF00466.15 ETS63564.1 - 3.7e-17 62.0 0.0 6e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Nucleoplasmin PF03066.10 ETS63564.1 - 0.19 11.2 10.2 0.38 10.2 7.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin ANAPC15 PF15243.1 ETS63564.1 - 0.85 9.7 10.8 2.2 8.4 7.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 NOA36 PF06524.7 ETS63564.1 - 3.4 6.8 10.0 4.9 6.3 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 ETS63564.1 - 3.6 7.3 6.6 7.9 6.2 4.6 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 ETS63564.1 - 7.1 6.1 12.1 14 5.1 8.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region HEAT_2 PF13646.1 ETS63565.1 - 2.3e-31 107.8 3.2 3.6e-16 59.2 1.1 2.8 2 2 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 ETS63565.1 - 2.1e-19 67.9 1.2 0.00051 20.2 0.0 6.8 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 ETS63565.1 - 3.7e-12 45.2 3.3 0.098 12.7 0.0 6.3 6 1 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 ETS63565.1 - 1.5e-10 41.1 4.2 0.014 15.9 0.0 5.6 3 2 2 6 6 6 5 HEAT-like repeat Arm PF00514.18 ETS63565.1 - 0.0003 20.4 0.2 2.5 8.0 0.0 4.2 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 ETS63565.1 - 0.0053 16.6 2.1 0.043 13.7 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion UPF0147 PF03685.8 ETS63565.1 - 0.0088 15.8 0.1 0.86 9.5 0.0 3.1 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0147) DUF1546 PF07571.8 ETS63565.1 - 0.06 13.4 0.0 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) CLTH PF10607.4 ETS63566.1 - 2.2e-33 114.9 0.0 2.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 ETS63566.1 - 3.5e-09 36.0 1.9 4.2e-09 35.8 0.0 2.2 3 0 0 3 3 3 1 LisH DWNN PF08783.6 ETS63567.1 - 9e-35 118.4 0.0 1.6e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC PF00098.18 ETS63567.1 - 7e-06 25.7 1.6 1.4e-05 24.7 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 ETS63567.1 - 9.1e-05 22.3 0.1 0.0064 16.4 0.0 2.5 1 1 1 2 2 2 1 U-box domain zf-CCHC_3 PF13917.1 ETS63567.1 - 0.00027 20.6 0.3 0.00093 18.8 0.2 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 ETS63567.1 - 0.00099 18.5 3.9 0.0024 17.3 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 ETS63567.1 - 0.0029 17.5 13.8 0.0029 17.5 9.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 ETS63567.1 - 0.02 14.3 0.6 0.05 13.0 0.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Frigida PF07899.6 ETS63567.1 - 0.18 10.5 1.4 0.29 9.8 1.0 1.2 1 0 0 1 1 1 0 Frigida-like protein zf-RING_2 PF13639.1 ETS63567.1 - 0.21 11.4 12.6 0.47 10.3 8.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 ETS63567.1 - 2.1 8.0 15.5 4 7.1 10.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.11 ETS63567.1 - 4.1 7.8 6.9 10 6.5 4.8 1.6 1 0 0 1 1 1 0 Trm112p-like protein zf-RING_6 PF14835.1 ETS63567.1 - 4.5 7.1 9.2 0.38 10.5 3.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 ETS63567.1 - 7.2 6.5 13.8 17 5.3 9.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LCAT PF02450.10 ETS63568.1 - 3.2e-87 293.0 0.2 9.4e-87 291.4 0.1 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 ETS63568.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) MOR2-PAG1_N PF14222.1 ETS63569.1 - 3.7e-158 527.6 0.0 7.4e-158 526.6 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 ETS63569.1 - 2.4e-55 188.1 1.0 4e-27 95.6 0.0 3.5 4 0 0 4 4 4 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 ETS63569.1 - 5.9e-30 103.6 5.4 1.3e-12 46.1 0.0 4.2 3 1 0 3 3 3 3 Cell morphogenesis central region DUF2454 PF10521.4 ETS63569.1 - 0.054 12.4 0.0 0.17 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) Acid_PPase PF12689.2 ETS63570.1 - 6.3e-59 198.3 0.0 7.6e-59 198.1 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase DUF903 PF06004.7 ETS63570.1 - 0.00064 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) HAD_2 PF13419.1 ETS63570.1 - 0.0038 17.4 0.4 0.14 12.3 0.0 2.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS63570.1 - 0.11 12.6 0.0 0.95 9.5 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pex2_Pex12 PF04757.9 ETS63571.1 - 5.9e-41 140.3 5.9 9.8e-41 139.6 4.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 ETS63571.1 - 0.0035 16.9 2.8 0.0072 15.9 0.6 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS63571.1 - 0.0038 17.0 0.8 0.85 9.5 0.1 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 ETS63571.1 - 0.44 10.6 6.1 0.24 11.4 1.5 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RIX1 PF08167.7 ETS63572.1 - 3.1e-12 46.4 1.0 2.5e-11 43.5 0.3 2.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Sec10 PF07393.6 ETS63573.1 - 2.5e-277 921.8 0.0 3e-277 921.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 CTD_bind PF04818.8 ETS63573.1 - 0.027 14.7 0.5 2.9 8.1 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase II-binding domain. Spectrin PF00435.16 ETS63573.1 - 0.074 13.3 0.1 0.33 11.2 0.1 2.2 1 0 0 1 1 1 0 Spectrin repeat Glyco_hydro_16 PF00722.16 ETS63574.1 - 9.5e-34 116.2 4.8 1.4e-33 115.7 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 ETS63574.1 - 0.00079 19.3 14.3 0.0018 18.2 9.9 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF1080 PF06439.6 ETS63574.1 - 0.016 15.0 0.6 0.025 14.4 0.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Laminin_G_3 PF13385.1 ETS63574.1 - 0.017 15.3 6.3 0.031 14.5 4.4 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF4660 PF15559.1 ETS63574.1 - 0.099 12.7 0.3 0.62 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Sld5 PF05916.6 ETS63575.1 - 2e-11 44.0 0.0 3.1e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein TPR_11 PF13414.1 ETS63577.1 - 9.7e-26 89.2 10.7 1.5e-05 24.5 0.0 7.4 6 1 1 7 7 7 6 TPR repeat TPR_16 PF13432.1 ETS63577.1 - 2.2e-18 66.3 14.5 4.2e-05 24.0 0.2 8.2 7 2 1 8 8 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETS63577.1 - 2e-17 61.6 12.4 0.055 13.4 0.0 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETS63577.1 - 8e-15 53.4 1.4 0.11 12.3 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS63577.1 - 9.2e-15 54.3 18.7 0.0016 18.3 0.3 6.7 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS63577.1 - 1.1e-11 44.9 8.9 3.2e-05 24.1 0.4 7.1 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS63577.1 - 1.1e-11 43.8 8.0 0.21 11.2 0.1 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETS63577.1 - 5.3e-10 39.0 4.9 1.1 9.8 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS63577.1 - 4.4e-09 36.1 20.6 0.0002 21.6 0.8 10.0 9 3 2 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS63577.1 - 9.9e-09 34.7 0.0 1.4 9.2 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 ETS63577.1 - 1.5e-05 24.2 5.7 0.0017 17.4 0.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS63577.1 - 3e-05 23.4 10.4 3.9 7.4 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS63577.1 - 3.9e-05 23.6 6.3 0.23 11.5 1.5 5.0 4 3 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETS63577.1 - 0.0004 20.1 6.4 0.025 14.4 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 ETS63577.1 - 0.013 15.6 0.7 3.9 7.6 0.1 2.8 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_20 PF14561.1 ETS63577.1 - 0.046 13.8 11.5 0.89 9.7 0.0 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS63577.1 - 0.69 10.5 10.3 12 6.6 0.1 5.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Nup88 PF10168.4 ETS63578.1 - 4.8e-16 57.7 0.0 1.5e-10 39.6 0.0 3.2 3 0 0 3 3 3 3 Nuclear pore component UDG PF03167.14 ETS63578.1 - 0.041 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Sec1 PF00995.18 ETS63579.1 - 1.5e-150 502.6 0.0 1.7e-150 502.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CDK2AP PF09806.4 ETS63580.1 - 0.8 9.9 5.8 1.3 9.2 4.0 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Pkinase PF00069.20 ETS63581.1 - 5.1e-41 140.5 0.0 1.1e-24 87.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63581.1 - 1e-16 60.8 0.0 5.9e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase UQ_con PF00179.21 ETS63582.1 - 4.7e-45 152.4 0.0 5.4e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Syntaxin-18_N PF10496.4 ETS63583.1 - 1.1e-14 53.9 0.0 1.2e-13 50.7 0.0 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 ETS63583.1 - 0.027 14.1 1.7 0.027 14.1 1.2 2.1 2 0 0 2 2 2 0 SNARE domain Glyco_transf_22 PF03901.12 ETS63584.1 - 5e-32 111.4 6.9 6.8e-32 110.9 4.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XAP5 PF04921.9 ETS63585.1 - 9.4e-94 313.4 7.2 9.4e-94 313.4 5.0 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator Gemin6 PF06372.7 ETS63585.1 - 0.23 10.7 1.4 6 6.1 0.1 2.3 2 0 0 2 2 2 0 Gemin6 protein ACT_7 PF13840.1 ETS63586.1 - 5e-16 57.9 0.0 2.1e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 ACT domain AA_permease PF00324.16 ETS63588.1 - 7.3e-130 433.4 44.1 9.2e-130 433.1 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS63588.1 - 1.9e-40 138.6 46.7 2.6e-40 138.2 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease Flavin_Reduct PF01613.13 ETS63591.1 - 4.5e-20 72.0 0.1 6.4e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Methyltransf_23 PF13489.1 ETS63592.1 - 7.4e-17 61.5 0.7 1.3e-16 60.7 0.5 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS63592.1 - 1.3e-14 54.4 0.0 2.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS63592.1 - 3.4e-12 46.6 0.0 8.5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63592.1 - 4.9e-12 46.4 0.0 9.7e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS63592.1 - 3.7e-11 42.8 0.0 5.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS63592.1 - 5.2e-07 29.9 0.0 9.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS63592.1 - 1.1e-06 28.0 0.1 2.2e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 ETS63592.1 - 2.6e-05 23.2 0.0 0.00024 20.0 0.0 2.0 1 1 0 1 1 1 1 DREV methyltransferase DUF938 PF06080.7 ETS63592.1 - 9.1e-05 22.0 0.1 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 ETS63592.1 - 9.6e-05 21.6 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS63592.1 - 0.00014 21.8 0.5 0.00058 19.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 ETS63592.1 - 0.0011 18.1 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 ETS63592.1 - 0.0018 17.7 0.1 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CmcI PF04989.7 ETS63592.1 - 0.015 14.6 0.4 0.026 13.8 0.3 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase NPV_P10 PF05531.7 ETS63592.1 - 0.018 15.2 0.2 0.041 14.1 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TehB PF03848.9 ETS63592.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Monooxygenase_B PF04744.7 ETS63592.1 - 0.16 10.6 0.2 0.24 10.0 0.1 1.2 1 0 0 1 1 1 0 Monooxygenase subunit B protein TFCD_C PF12612.3 ETS63593.1 - 1.9e-30 105.7 0.0 3.9e-29 101.4 0.0 2.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.2 ETS63593.1 - 0.015 15.6 0.2 2.1 8.7 0.0 3.9 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 ETS63593.1 - 0.017 14.9 0.0 0.27 11.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 ETS63593.1 - 0.029 14.2 0.1 20 4.9 0.0 3.7 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 ETS63593.1 - 0.043 13.9 0.0 0.043 13.9 0.0 8.2 9 0 0 9 9 9 0 HEAT repeat HEAT_2 PF13646.1 ETS63593.1 - 0.046 13.9 26.0 0.11 12.7 0.1 6.8 6 2 1 7 7 7 0 HEAT repeats HEAT_PBS PF03130.11 ETS63593.1 - 0.15 12.5 0.0 0.15 12.5 0.0 6.9 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat Lipase_3 PF01764.20 ETS63594.1 - 1.1e-17 63.9 0.0 3.9e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2048 PF09752.4 ETS63594.1 - 0.049 12.5 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) SLX9 PF15341.1 ETS63595.1 - 3e-20 72.8 6.6 4.9e-20 72.1 4.6 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Prothymosin PF03247.9 ETS63595.1 - 0.0046 17.0 2.7 0.0075 16.3 1.9 1.3 1 0 0 1 1 1 1 Prothymosin/parathymosin family DUF4335 PF14233.1 ETS63595.1 - 0.056 12.9 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) TP_methylase PF00590.15 ETS63595.1 - 0.062 13.0 1.2 0.098 12.3 0.7 1.3 1 1 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases CAF-1_p150 PF11600.3 ETS63595.1 - 0.26 10.6 7.5 0.49 9.7 5.2 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAPS PF04499.10 ETS63595.1 - 0.27 9.8 3.7 0.33 9.5 2.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein p450 PF00067.17 ETS63596.1 - 2.8e-53 181.0 0.0 3.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mannosyl_trans PF05007.8 ETS63597.1 - 2.7e-59 200.9 19.5 1.9e-57 194.8 8.3 2.5 3 0 0 3 3 3 2 Mannosyltransferase (PIG-M) UPF0061 PF02696.9 ETS63598.1 - 1.7e-84 283.8 0.0 2.3e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Cupin_8 PF13621.1 ETS63599.1 - 1.5e-22 80.2 0.2 2.2e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETS63599.1 - 5.1e-15 55.7 0.7 1e-14 54.7 0.5 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 ETS63599.1 - 0.023 14.1 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 Cupin domain GPI PF06560.6 ETS63599.1 - 0.035 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Peptidase_C48 PF02902.14 ETS63600.1 - 1.1e-38 133.0 0.0 7.1e-36 123.8 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SGT1 PF07093.6 ETS63601.1 - 1.1e-135 453.3 11.9 1.9e-135 452.5 8.2 1.3 1 1 0 1 1 1 1 SGT1 protein PG_binding_2 PF08823.6 ETS63601.1 - 0.026 14.6 0.0 0.087 12.9 0.0 1.9 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DIL PF01843.14 ETS63602.1 - 3.5e-27 94.3 0.3 7e-27 93.3 0.2 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 ETS63602.1 - 1.6e-15 57.1 0.0 5.2e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS63602.1 - 2.7e-13 48.9 1.3 7.1e-08 31.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETS63602.1 - 8.6e-12 45.2 0.1 6.1e-06 26.5 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS63602.1 - 7.9e-11 41.1 0.0 8.5e-05 22.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS63602.1 - 2.4e-08 33.9 0.1 0.00088 19.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF2992 PF11208.3 ETS63602.1 - 5.6 6.8 8.9 0.28 11.0 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) DUF2146 PF10220.4 ETS63602.1 - 9.7 4.0 8.5 0.27 9.1 1.5 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) DSHCT PF08148.7 ETS63604.1 - 5.1e-57 192.0 0.3 1.5e-56 190.5 0.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 ETS63604.1 - 1.8e-22 79.6 0.0 3.4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS63604.1 - 2.7e-06 27.1 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 ETS63604.1 - 0.00035 19.8 0.8 0.001 18.2 0.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain ResIII PF04851.10 ETS63604.1 - 0.0039 17.0 0.1 0.042 13.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF952 PF06108.7 ETS63605.1 - 8.2e-17 60.8 0.0 1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Mit_KHE1 PF10173.4 ETS63606.1 - 7.8e-53 179.1 0.1 7.8e-53 179.1 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Nbl1_Borealin_N PF10444.4 ETS63607.1 - 3.9e-16 58.1 1.2 8.1e-16 57.1 0.8 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Dfp1_Him1_M PF08630.5 ETS63608.1 - 1.3e-30 105.7 0.1 2.2e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 ETS63608.1 - 1.6e-21 75.6 0.7 2.9e-21 74.8 0.5 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 ETS63608.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Arf PF00025.16 ETS63610.1 - 2.3e-79 264.6 0.1 2.7e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 ETS63610.1 - 2.8e-14 52.7 0.0 3.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 ETS63610.1 - 5.4e-13 48.6 0.0 5.8e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 ETS63610.1 - 3.3e-12 45.8 1.3 4.3e-09 35.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 ETS63610.1 - 3.7e-11 42.5 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS63610.1 - 3e-09 37.3 0.0 4.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS63610.1 - 6e-06 26.1 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS63610.1 - 0.0044 16.4 0.1 0.028 13.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 ETS63610.1 - 0.0068 15.4 0.3 0.019 14.0 0.1 1.6 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 ETS63610.1 - 0.075 12.9 0.1 0.14 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETS63610.1 - 0.13 11.7 0.2 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_CH_N PF12471.3 ETS63611.1 - 4.9e-88 293.8 0.0 7.1e-88 293.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 ETS63611.1 - 7.3e-13 48.1 0.0 1.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ecl1 PF12855.2 ETS63615.1 - 0.01 15.1 0.4 0.022 14.0 0.3 1.5 1 0 0 1 1 1 0 Life-span regulatory factor WSC PF01822.14 ETS63615.1 - 0.015 15.1 2.1 0.041 13.8 1.5 1.7 1 0 0 1 1 1 0 WSC domain Thg1C PF14413.1 ETS63616.1 - 2.6e-45 153.0 0.0 5.5e-45 151.9 0.0 1.5 1 1 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 ETS63616.1 - 1.3e-43 147.8 0.0 2e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase G6B PF15096.1 ETS63616.1 - 0.13 11.8 0.3 0.25 10.8 0.1 1.6 2 0 0 2 2 2 0 G6B family Ferric_reduct PF01794.14 ETS63617.1 - 4e-19 68.9 14.8 4e-19 68.9 10.3 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS63617.1 - 6.9e-13 48.3 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 ETS63617.1 - 8.9e-12 45.1 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4149 PF13664.1 ETS63617.1 - 4.4 7.4 14.3 1 9.4 0.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) NAD_binding_10 PF13460.1 ETS63618.1 - 1e-20 74.5 0.0 1.5e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS63618.1 - 3.3e-14 52.6 0.0 4.6e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS63618.1 - 6.2e-11 42.1 0.1 1.4e-09 37.7 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS63618.1 - 1.3e-10 40.6 0.0 3.7e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 ETS63618.1 - 3.3e-10 39.1 0.1 1.3e-09 37.2 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS63618.1 - 3.4e-08 32.7 0.2 0.00025 20.0 0.2 3.1 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 ETS63618.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 ETS63618.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS63618.1 - 0.013 15.3 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 ETS63618.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HhH-GPD PF00730.20 ETS63619.1 - 2.4e-12 47.0 0.0 4.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2360 PF10152.4 ETS63619.1 - 0.49 10.6 4.8 1.9 8.7 0.8 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) eIF3_N PF09440.5 ETS63620.1 - 6.9e-46 155.7 0.3 1.3e-45 154.7 0.2 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 ETS63620.1 - 1.8e-10 41.0 0.1 7.6e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 PCI domain MFS_1 PF07690.11 ETS63621.1 - 8.3e-11 41.1 12.8 8.3e-11 41.1 8.9 2.9 2 2 0 2 2 2 1 Major Facilitator Superfamily LtrA PF06772.6 ETS63622.1 - 7e-23 81.1 13.4 9.3e-23 80.6 9.3 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Zn_clus PF00172.13 ETS63623.1 - 1.9e-06 27.6 13.6 4.1e-06 26.5 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 ETS63623.1 - 1.5 6.8 7.8 3.5 5.5 5.4 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UCH PF00443.24 ETS63624.1 - 8.8e-58 195.5 0.0 1.2e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS63624.1 - 2.9e-30 105.7 0.3 7.8e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Raffinose_syn PF05691.7 ETS63625.1 - 2.1e-20 71.9 0.1 8.8e-19 66.5 0.1 2.5 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 MFS_1 PF07690.11 ETS63626.1 - 9.2e-32 110.1 20.2 9.2e-32 110.1 14.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily EXS PF03124.9 ETS63626.1 - 0.0017 17.4 1.4 0.0098 14.9 1.0 2.2 1 1 0 1 1 1 1 EXS family Vpu PF00558.14 ETS63626.1 - 0.21 11.1 1.0 0.43 10.1 0.1 1.9 2 0 0 2 2 2 0 Vpu protein Wzy_C PF04932.10 ETS63626.1 - 0.87 9.3 9.8 0.11 12.2 0.3 2.9 2 1 1 3 3 3 0 O-Antigen ligase DASH_Dad4 PF08650.5 ETS63627.1 - 5.4e-18 64.6 2.8 5.9e-18 64.5 1.9 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 UBN2_2 PF14227.1 ETS63627.1 - 0.019 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type GTPase_Cys_C PF12631.2 ETS63627.1 - 0.046 14.1 0.7 0.097 13.0 0.5 1.7 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Ins134_P3_kin PF05770.6 ETS63627.1 - 0.059 12.3 0.1 0.067 12.1 0.1 1.0 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase DASH_Dad1 PF08649.5 ETS63627.1 - 0.11 12.1 0.6 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 Hydrolase PF00702.21 ETS63628.1 - 3e-22 80.1 0.0 3.2e-21 76.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETS63628.1 - 3.5e-22 78.5 0.2 9.5e-22 77.1 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 ETS63628.1 - 8.3e-19 68.5 0.0 1.5e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS63628.1 - 0.00026 20.8 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS63628.1 - 0.02 14.4 0.0 0.065 12.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS63628.1 - 0.047 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Bac_rhodopsin PF01036.13 ETS63629.1 - 2.3e-44 151.3 16.4 2.8e-44 151.0 11.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein ResIII PF04851.10 ETS63629.1 - 0.073 12.8 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arteri_Gl PF00951.13 ETS63629.1 - 1.3 8.6 7.5 0.084 12.4 0.4 2.0 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein UQ_con PF00179.21 ETS63630.1 - 1.1e-40 138.3 0.0 1.3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETS63630.1 - 0.00025 20.8 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 ETS63630.1 - 0.032 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 ETS63630.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B PLDc PF00614.17 ETS63631.1 - 1.3e-14 53.3 0.3 2.2e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 ETS63631.1 - 1.2e-11 44.4 0.0 2.5e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 ETS63631.1 - 2.3e-10 40.2 0.0 6.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 PX domain Rrp15p PF07890.7 ETS63632.1 - 4.6e-33 114.0 5.9 4.6e-33 114.0 4.1 2.3 1 1 1 2 2 2 1 Rrp15p YL1 PF05764.8 ETS63632.1 - 0.49 9.9 19.9 0.024 14.2 8.9 2.1 2 0 0 2 2 2 0 YL1 nuclear protein LZ_Tnp_IS66 PF13007.2 ETS63632.1 - 6.4 7.5 25.6 0.48 11.1 3.1 3.9 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain ATP-grasp_2 PF08442.5 ETS63633.1 - 4.9e-73 244.8 0.7 7.4e-73 244.2 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 ETS63633.1 - 4.5e-22 78.2 1.2 1e-21 77.1 0.5 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 ETS63633.1 - 1.6e-12 47.1 0.5 3.2e-12 46.1 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 ETS63633.1 - 5.7e-05 22.7 0.1 0.00021 20.9 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 ETS63633.1 - 0.00044 20.0 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PepSY PF03413.14 ETS63633.1 - 0.0081 16.7 0.7 1.5 9.5 0.1 3.5 3 0 0 3 3 3 1 Peptidase propeptide and YPEB domain ATP-grasp PF02222.17 ETS63633.1 - 0.017 14.4 0.0 0.052 12.9 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain PASTA PF03793.14 ETS63633.1 - 0.18 11.4 0.4 0.81 9.3 0.1 2.3 2 0 0 2 2 2 0 PASTA domain Ceramidase_alk PF04734.8 ETS63634.1 - 5.2e-216 718.6 0.0 7.8e-214 711.4 0.0 2.6 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase MCM PF00493.18 ETS63635.1 - 3.8e-136 453.2 0.4 5.6e-136 452.6 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS63635.1 - 5.3e-20 72.1 0.2 3.8e-19 69.3 0.0 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS63635.1 - 1.6e-07 30.7 0.0 7.8e-07 28.4 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETS63635.1 - 0.0023 17.4 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 ETS63635.1 - 0.0034 17.0 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS63635.1 - 0.037 13.7 0.0 0.13 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4398 PF14346.1 ETS63636.1 - 0.05 13.6 6.6 0.066 13.2 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF1003 PF06210.6 ETS63636.1 - 2.8 7.9 5.3 6.1 6.8 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Prp31_C PF09785.4 ETS63637.1 - 2.6e-41 140.9 3.6 2.6e-41 140.9 2.5 2.1 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 ETS63637.1 - 6.9e-37 126.0 0.4 6.9e-37 126.0 0.3 1.6 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 ETS63637.1 - 3.1e-19 68.5 0.1 5.4e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain CD99L2 PF12301.3 ETS63637.1 - 0.062 12.9 9.8 0.18 11.5 6.8 1.8 1 0 0 1 1 1 0 CD99 antigen like protein 2 AMP-binding PF00501.23 ETS63638.1 - 4e-86 289.0 0.0 7e-86 288.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N PF00107.21 ETS63638.1 - 7.4e-18 64.3 3.0 1e-17 63.9 0.6 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AMP-binding_C PF13193.1 ETS63638.1 - 7.8e-17 61.9 0.1 2.3e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N_2 PF13602.1 ETS63638.1 - 1.4e-10 42.1 0.4 9.2e-10 39.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS63638.1 - 0.0016 18.1 1.4 0.0095 15.6 0.0 3.0 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 ETS63638.1 - 0.079 12.9 0.1 0.33 10.9 0.1 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MOSC_N PF03476.11 ETS63639.1 - 1.3e-19 70.0 0.0 3.3e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 ETS63639.1 - 3.2e-10 39.5 0.0 5.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain CorA PF01544.13 ETS63640.1 - 4.7e-46 157.1 0.3 6.8e-46 156.6 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 ETS63640.1 - 0.057 13.7 0.1 0.16 12.3 0.1 1.7 2 0 0 2 2 2 0 ACT domain Baculo_PEP_C PF04513.7 ETS63640.1 - 0.089 12.6 0.9 0.2 11.4 0.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 ETS63640.1 - 0.16 11.6 0.3 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) SUR7 PF06687.7 ETS63641.1 - 3.9e-29 101.7 2.9 6.6e-29 101.0 2.0 1.3 1 0 0 1 1 1 1 SUR7/PalI family MerC PF03203.9 ETS63642.1 - 2.8 8.3 8.2 0.3 11.4 1.9 2.2 2 1 0 2 2 2 0 MerC mercury resistance protein Ferritin_2 PF13668.1 ETS63643.1 - 1.4e-18 67.1 0.1 2e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain CDC37_N PF03234.9 ETS63645.1 - 0.034 14.4 1.4 0.045 14.0 1.0 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding HEXIM PF15313.1 ETS63645.1 - 0.085 13.0 0.5 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein HTH_psq PF05225.11 ETS63645.1 - 0.097 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF972 PF06156.8 ETS63645.1 - 0.11 12.8 0.6 0.17 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ISG65-75 PF11727.3 ETS63645.1 - 0.16 11.0 1.8 0.2 10.6 1.3 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Fib_alpha PF08702.5 ETS63645.1 - 0.26 11.4 1.9 0.43 10.7 1.3 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Aldolase_II PF00596.16 ETS63646.1 - 5.8e-43 146.6 0.0 7.2e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SET PF00856.23 ETS63647.1 - 3.4e-20 72.9 0.2 3.4e-20 72.9 0.1 3.6 4 1 0 4 4 4 1 SET domain Zn_clus PF00172.13 ETS63648.1 - 9.8e-07 28.5 10.3 1.7e-06 27.8 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS63648.1 - 4.1e-05 22.5 0.0 0.00033 19.6 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L7Ae PF01248.21 ETS63650.1 - 9.6e-21 73.1 0.6 1.8e-20 72.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HTH_Tnp_Tc5 PF03221.11 ETS63651.1 - 6e-13 48.4 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 ETS63651.1 - 0.00018 20.8 0.1 0.00043 19.6 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.1 ETS63651.1 - 0.018 14.5 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MAPEG PF01124.13 ETS63652.1 - 1.6e-13 50.3 5.1 2.1e-13 50.0 3.5 1.1 1 0 0 1 1 1 1 MAPEG family Iso_dh PF00180.15 ETS63653.1 - 1.8e-85 286.9 0.0 2.1e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L13 PF00572.13 ETS63654.1 - 5.8e-48 162.1 0.5 8.7e-48 161.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 DUF1115 PF06544.7 ETS63656.1 - 3.5e-15 55.7 0.0 6.8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Sigma70_r4_2 PF08281.7 ETS63656.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Peptidase_M43 PF05572.8 ETS63657.1 - 4.4e-17 62.1 0.0 7.8e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 ETS63657.1 - 0.00025 21.0 0.3 0.00047 20.1 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 ETS63657.1 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 ETS63657.1 - 0.0016 19.0 3.6 0.0037 17.7 0.4 2.6 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 ETS63657.1 - 0.0099 15.9 3.0 0.086 12.8 2.1 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 ETS63657.1 - 0.031 13.8 0.3 0.065 12.7 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 ETS63657.1 - 0.044 12.6 0.2 0.15 10.9 0.1 1.8 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M54 PF07998.6 ETS63657.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 ADH_N PF08240.7 ETS63658.1 - 1e-27 96.0 0.2 3e-27 94.5 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS63658.1 - 8.6e-21 73.8 3.0 4.5e-19 68.2 2.1 2.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63658.1 - 0.0042 17.9 0.1 0.1 13.4 0.0 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fer2_BFD PF04324.10 ETS63658.1 - 0.051 13.6 0.5 8.7 6.4 0.2 2.5 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain PrmA PF06325.8 ETS63658.1 - 0.056 12.5 0.7 0.088 11.9 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AdoHcyase_NAD PF00670.16 ETS63658.1 - 0.069 12.9 0.6 4.3 7.1 0.2 2.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS63658.1 - 0.16 11.5 0.7 0.31 10.5 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.16 ETS63659.1 - 4.7e-53 179.8 0.0 1e-52 178.7 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family Peptidase_C48 PF02902.14 ETS63659.1 - 1.2e-27 96.9 0.0 4.1e-19 69.0 0.0 2.7 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Methyltransf_28 PF02636.12 ETS63661.1 - 6.7e-36 123.9 0.0 1.2e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 ETS63661.1 - 3.9e-05 23.6 0.0 0.00016 21.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 ETS63661.1 - 4.1e-05 22.7 0.0 7.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 ETS63661.1 - 0.0035 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 ETS63661.1 - 0.028 13.3 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.1 ETS63661.1 - 0.035 13.7 0.2 0.087 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63661.1 - 0.39 11.3 1.3 0.73 10.4 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain HECT PF00632.20 ETS63662.1 - 6.1e-91 304.8 0.0 9.4e-91 304.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GST_C_3 PF14497.1 ETS63663.1 - 1.6e-08 34.8 0.0 2.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS63663.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_N PF08240.7 ETS63664.1 - 1.1e-27 95.9 0.9 1.8e-27 95.2 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS63664.1 - 4.6e-10 39.1 0.0 8.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS63664.1 - 0.002 18.9 0.0 0.004 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase OB_NTP_bind PF07717.11 ETS63665.1 - 3.8e-13 49.2 0.0 7.2e-12 45.1 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS63665.1 - 3.2e-12 46.3 0.0 8.1e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS63665.1 - 1.4e-08 34.4 0.0 3.5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS63665.1 - 2.1e-06 27.3 0.2 0.022 14.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS63665.1 - 0.0016 18.5 0.0 0.0099 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 ETS63665.1 - 0.006 15.5 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 ETS63665.1 - 0.0083 15.8 1.3 0.084 12.6 0.2 3.2 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 ETS63665.1 - 0.014 14.6 0.1 0.061 12.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 ETS63665.1 - 0.026 14.0 0.1 0.069 12.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 ETS63665.1 - 0.039 13.7 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 ETS63665.1 - 0.04 13.3 0.4 0.4 10.0 0.2 2.7 1 1 0 1 1 1 0 AAA-like domain KaiC PF06745.8 ETS63665.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 ETS63665.1 - 0.21 11.1 0.9 0.97 9.0 0.6 2.0 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS63665.1 - 0.27 11.5 0.2 0.63 10.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 ETS63665.1 - 0.6 9.4 12.8 3.8 6.8 5.6 2.2 2 0 0 2 2 2 0 Vta1 like Pkinase PF00069.20 ETS63666.1 - 6.4e-71 238.5 0.0 8.2e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63666.1 - 5.8e-29 100.9 0.0 8.7e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS63666.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family NMT1 PF09084.6 ETS63667.1 - 0.0059 16.2 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 ETS63667.1 - 0.018 14.4 0.1 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 NMT1-like family GMC_oxred_N PF00732.14 ETS63668.1 - 3.7e-50 170.7 0.0 5.8e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS63668.1 - 3.1e-34 118.3 0.0 5.2e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS63668.1 - 4.4e-06 25.8 0.3 0.00042 19.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS63668.1 - 0.00011 21.1 0.4 0.039 12.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS63668.1 - 0.00043 20.2 0.3 0.0022 17.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS63668.1 - 0.0012 17.8 0.3 0.0019 17.1 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS63668.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS63668.1 - 0.08 12.7 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 ETS63668.1 - 0.13 11.3 0.1 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 ETS63668.1 - 0.21 10.1 0.1 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Voldacs PF03517.8 ETS63669.1 - 3.2e-29 101.5 0.2 7.1e-28 97.1 0.0 2.7 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling Calcipressin PF04847.7 ETS63669.1 - 8.6e-29 100.4 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Calcipressin Ribosomal_L36e PF01158.13 ETS63670.1 - 1e-36 124.8 5.0 1.6e-36 124.2 3.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L36e Lactamase_B PF00753.22 ETS63671.1 - 2.8e-17 63.0 3.3 3.6e-17 62.6 2.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS63671.1 - 0.033 13.7 0.5 0.046 13.2 0.3 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.16 ETS63672.1 - 2.8e-186 619.6 0.0 2.8e-138 461.3 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 ETS63672.1 - 0.0088 15.4 0.1 3.6 6.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 GCV_T PF01571.16 ETS63673.1 - 6.3e-67 225.0 0.3 2e-66 223.3 0.1 1.8 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETS63673.1 - 2.7e-26 91.4 0.1 6.5e-26 90.1 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Abhydrolase_1 PF00561.15 ETS63675.1 - 6.1e-26 91.3 0.1 1.3e-25 90.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS63675.1 - 1.3e-25 90.6 0.8 2e-25 89.9 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63675.1 - 3.1e-11 43.2 0.0 2.4e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS63675.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 ETS63675.1 - 0.13 10.7 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family NUFIP1 PF10453.4 ETS63676.1 - 7e-16 57.4 2.0 7e-16 57.4 1.4 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 ETS63676.1 - 4.7e-05 22.9 1.9 0.0001 21.8 1.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SNF2_N PF00176.18 ETS63677.1 - 1.2e-54 185.1 0.0 1.7e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 ETS63677.1 - 1.9e-07 30.7 9.3 5.7e-07 29.2 6.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS63677.1 - 2.4e-07 30.3 8.4 5.3e-07 29.1 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS63677.1 - 8.7e-07 28.5 6.0 2e-06 27.3 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS63677.1 - 6.6e-06 26.0 9.9 1.3e-05 25.0 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS63677.1 - 0.00014 21.4 6.6 0.00033 20.3 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS63677.1 - 0.00017 21.2 4.0 0.00036 20.1 2.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.26 ETS63677.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 ETS63677.1 - 0.29 11.0 8.5 0.69 9.8 5.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 ETS63677.1 - 1.6 8.3 10.1 1.2 8.8 4.2 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L4 PF00573.17 ETS63680.1 - 1.2e-69 233.5 0.0 1.8e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 ETS63682.1 - 1.7e-42 144.4 0.3 2e-42 144.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SPA PF08616.5 ETS63683.1 - 3.5e-06 26.7 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Ribosomal_L35p PF01632.14 ETS63685.1 - 0.0085 15.9 2.5 0.0085 15.9 1.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L35 HCNGP PF07818.8 ETS63686.1 - 2.4e-16 59.5 0.0 4.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein PEX11 PF05648.9 ETS63687.1 - 3.3e-17 62.5 0.0 1.4e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PHD PF00628.24 ETS63690.1 - 4.3e-11 42.3 8.4 9.8e-11 41.1 5.9 1.6 1 0 0 1 1 1 1 PHD-finger RAP1 PF07218.6 ETS63690.1 - 4.7 5.1 6.7 9.6 4.1 4.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3485 PF11984.3 ETS63692.1 - 0.0082 15.2 0.1 0.0091 15.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3485) TrbC PF04956.8 ETS63692.1 - 0.021 14.8 0.1 0.023 14.6 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family Cutinase PF01083.17 ETS63693.1 - 3.6e-35 121.3 2.7 4.1e-35 121.1 1.8 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS63693.1 - 4e-05 23.1 0.1 5.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Glyco_hydro_3 PF00933.16 ETS63695.1 - 5.6e-86 288.2 0.0 8.3e-86 287.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS63695.1 - 9.9e-61 205.1 1.0 9e-60 202.0 0.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS63695.1 - 2.8e-14 52.7 0.0 5.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PPP4R2 PF09184.6 ETS63696.1 - 5.8e-13 49.0 0.1 5.8e-13 49.0 0.1 2.7 1 1 1 2 2 2 1 PPP4R2 ABC_tran PF00005.22 ETS63698.1 - 5e-49 166.1 0.0 4.1e-27 95.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS63698.1 - 1.4e-41 142.6 23.3 1.6e-24 86.7 5.6 3.7 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS63698.1 - 6.1e-12 45.2 0.1 0.02 14.1 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS63698.1 - 1.2e-11 45.1 0.0 0.033 14.1 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 ETS63698.1 - 2.7e-09 36.4 0.3 0.00015 21.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS63698.1 - 4.6e-08 33.6 2.5 2e-05 25.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 ETS63698.1 - 9.7e-07 28.3 0.2 0.017 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 ETS63698.1 - 1.9e-06 28.1 0.2 0.076 13.2 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS63698.1 - 9e-06 25.7 0.5 0.13 12.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETS63698.1 - 3.8e-05 23.8 0.4 0.56 10.3 0.1 4.0 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 ETS63698.1 - 6.9e-05 23.6 0.2 0.55 11.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 ETS63698.1 - 0.00016 20.6 0.3 0.059 12.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Zeta_toxin PF06414.7 ETS63698.1 - 0.00057 19.0 0.1 0.086 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 ETS63698.1 - 0.00062 19.2 0.4 0.036 13.5 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 ETS63698.1 - 0.0014 17.8 0.1 0.058 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS63698.1 - 0.0018 18.2 0.3 2.1 8.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 ETS63698.1 - 0.002 18.5 0.5 0.4 11.1 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 ETS63698.1 - 0.0029 17.1 2.0 0.29 10.5 0.1 2.6 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 ETS63698.1 - 0.011 15.6 3.4 0.067 13.0 0.0 3.2 4 0 0 4 4 4 0 Dynamin family AAA_18 PF13238.1 ETS63698.1 - 0.011 16.0 0.5 6.1 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETS63698.1 - 0.017 14.8 0.3 5.5 6.6 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETS63698.1 - 0.027 14.3 3.5 1.3 8.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 ETS63698.1 - 0.028 14.2 2.8 2.5 7.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 ETS63698.1 - 0.065 12.9 0.1 0.7 9.5 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase NB-ARC PF00931.17 ETS63698.1 - 0.09 11.6 0.2 2.8 6.7 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.7 ETS63698.1 - 0.15 11.7 2.3 6.2 6.4 0.1 3.1 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.1 ETS63698.1 - 0.15 11.9 0.1 15 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 ETS63698.1 - 0.17 12.0 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.10 ETS63698.1 - 0.32 9.6 0.0 0.63 8.6 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Gtr1_RagA PF04670.7 ETS63698.1 - 1.7 7.6 3.6 27 3.7 0.2 3.0 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region UQ_con PF00179.21 ETS63699.1 - 6.3e-16 58.0 0.0 8.6e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PigN PF04987.9 ETS63700.1 - 2.2e-90 303.4 18.7 1.5e-88 297.4 11.3 2.1 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 ETS63700.1 - 2.2e-05 23.9 0.6 0.0044 16.3 0.1 2.6 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETS63700.1 - 0.00057 19.1 0.0 0.00088 18.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Chromo PF00385.19 ETS63701.1 - 7.2e-07 28.7 0.1 1.9e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PI3Ka PF00613.15 ETS63702.1 - 1.1e-52 177.9 0.0 1.6e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETS63702.1 - 1.1e-43 149.4 0.0 9e-43 146.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 ETS63702.1 - 1.4e-37 128.6 0.0 2.4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 ETS63702.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins CTK3 PF12243.3 ETS63703.1 - 6.5e-40 135.9 0.0 9.9e-40 135.3 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Mito_carr PF00153.22 ETS63703.1 - 1.1e-38 130.7 9.8 2.6e-16 59.0 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CTK3_C PF12350.3 ETS63703.1 - 5.7e-12 45.4 8.8 6e-10 39.0 6.1 2.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Fungal_trans_2 PF11951.3 ETS63704.1 - 1.9e-11 43.1 3.9 1.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63704.1 - 0.00053 19.8 10.2 0.00093 19.0 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 ETS63705.1 - 2e-29 101.0 25.1 1.3e-10 40.7 0.4 11.8 8 4 6 14 14 14 9 TPR repeat TPR_1 PF00515.23 ETS63705.1 - 1.5e-22 78.1 11.7 0.0034 16.9 0.1 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETS63705.1 - 2e-19 67.8 30.5 0.0073 16.1 0.2 13.8 17 0 0 17 17 15 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETS63705.1 - 2.9e-19 69.2 73.6 0.00011 22.8 0.3 16.8 12 5 7 20 20 19 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETS63705.1 - 1.5e-18 65.3 15.0 0.0085 16.2 0.0 12.4 13 1 1 14 14 14 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETS63705.1 - 4e-18 65.1 33.5 7.4e-07 29.0 0.0 11.0 8 3 4 12 12 12 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETS63705.1 - 1.8e-16 58.5 5.6 0.34 10.8 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS63705.1 - 7.5e-13 48.6 34.0 0.0025 18.0 0.0 10.6 8 2 1 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS63705.1 - 3.8e-11 41.8 11.1 0.11 12.3 0.1 8.6 8 1 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 ETS63705.1 - 1.4e-09 37.9 8.6 7.6e-05 22.7 0.0 6.8 6 1 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETS63705.1 - 4.5e-09 36.1 81.6 0.0013 19.2 0.2 18.1 15 5 6 22 22 18 5 Tetratricopeptide repeat TPR_6 PF13174.1 ETS63705.1 - 1.9e-08 34.2 18.5 0.05 14.0 0.0 11.5 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS63705.1 - 0.02 14.7 28.8 0.36 10.7 0.6 8.2 7 2 3 10 10 8 0 Tetratricopeptide repeat ChAPs PF09295.5 ETS63705.1 - 0.078 11.7 0.1 0.33 9.6 0.0 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) NAD_binding_7 PF13241.1 ETS63706.1 - 9e-28 96.5 0.0 1.5e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 ETS63706.1 - 1.7e-21 75.2 0.2 2.8e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 ETS63706.1 - 3.3e-09 35.5 0.2 7e-09 34.5 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Cnd3 PF12719.2 ETS63707.1 - 1.7e-84 283.3 3.4 1.8e-83 279.9 0.3 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 ETS63707.1 - 1.5e-13 50.8 8.5 5.3e-08 33.0 0.4 4.7 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 ETS63707.1 - 2.1e-09 36.6 9.8 0.46 10.6 0.1 6.5 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 ETS63707.1 - 4e-06 27.1 9.7 0.19 12.2 0.0 5.9 4 1 1 5 5 5 2 HEAT-like repeat MMS19_N PF14500.1 ETS63707.1 - 0.00039 19.7 1.2 0.0057 15.9 0.1 2.8 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.2 ETS63707.1 - 0.012 15.4 0.8 7.5 6.3 0.1 3.8 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF4611 PF15387.1 ETS63707.1 - 0.014 15.5 18.5 4.1 7.6 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Arm PF00514.18 ETS63707.1 - 0.15 11.9 1.3 21 5.1 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 ETS63707.1 - 0.63 9.9 3.2 57 3.7 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) Nucleoplasmin PF03066.10 ETS63707.1 - 0.89 9.0 17.6 2.4 7.6 4.5 4.2 4 0 0 4 4 4 0 Nucleoplasmin RNase_PH PF01138.16 ETS63708.1 - 1.7e-24 86.6 0.0 3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETS63708.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PDT PF00800.13 ETS63709.1 - 8.7e-64 214.4 0.0 3.1e-63 212.6 0.0 2.0 2 0 0 2 2 2 1 Prephenate dehydratase Pil1 PF13805.1 ETS63709.1 - 6.6e-23 81.2 0.6 1.4e-22 80.1 0.4 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 zf-CCHC PF00098.18 ETS63710.1 - 0.0028 17.5 2.6 0.0028 17.5 1.8 5.2 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_4 PF14392.1 ETS63710.1 - 0.47 10.1 28.8 0.19 11.3 1.7 4.3 4 1 1 5 5 5 0 Zinc knuckle Zn_Tnp_IS91 PF14319.1 ETS63710.1 - 4.3 6.8 11.9 2.9 7.4 3.0 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain Arrestin_N PF00339.24 ETS63711.1 - 8.7e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sigma70_ECF PF07638.6 ETS63712.1 - 0.059 13.0 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 ECF sigma factor Oxidored_q2 PF00420.19 ETS63712.1 - 0.74 9.4 9.3 14 5.3 6.5 2.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Zn_clus PF00172.13 ETS63714.1 - 7e-08 32.2 6.0 1.1e-07 31.6 4.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.14 ETS63715.1 - 6.1e-29 100.8 0.0 6.4e-18 64.9 0.1 2.9 2 1 0 2 2 2 2 Formyl transferase Histone PF00125.19 ETS63717.1 - 3e-20 72.1 0.1 5.4e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETS63717.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF814 PF05670.8 ETS63718.1 - 1.7e-20 72.7 0.0 3.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF3027 PF11228.3 ETS63718.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF956 PF06115.6 ETS63718.1 - 0.09 12.3 0.9 0.21 11.1 0.4 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF956) Pkinase PF00069.20 ETS63719.1 - 6.9e-63 212.2 0.0 1.5e-62 211.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63719.1 - 6.7e-40 136.7 0.0 8.7e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS63719.1 - 5.9e-08 32.0 0.0 8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETS63719.1 - 0.085 12.1 0.1 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL MutS_V PF00488.16 ETS63720.1 - 4.6e-32 111.3 0.0 3.3e-28 98.7 0.0 2.3 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 ETS63720.1 - 3.2e-18 66.2 0.7 6e-18 65.3 0.5 1.4 1 0 0 1 1 1 1 MutS domain III WD40 PF00400.27 ETS63721.1 - 0.0013 18.5 0.0 1.2 9.1 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 ETS63722.1 - 1.2e-32 113.6 5.3 1.8e-32 113.0 3.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63722.1 - 1e-14 54.4 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS63722.1 - 4e-13 49.4 0.3 5.6e-11 42.4 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS63722.1 - 2e-05 24.3 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 ETS63722.1 - 0.0028 16.2 0.0 0.0038 15.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.7 ETS63722.1 - 0.01 15.5 0.0 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.13 ETS63722.1 - 0.013 14.8 0.0 0.34 10.1 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.11 ETS63723.1 - 1.7e-30 105.9 50.5 2.6e-30 105.3 35.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS63723.1 - 2e-07 29.9 33.4 0.00038 19.1 8.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS63723.1 - 0.00054 19.7 0.2 0.00054 19.7 0.2 3.4 4 0 0 4 4 4 1 MFS_1 like family F-box-like PF12937.2 ETS63724.1 - 0.047 13.4 0.0 0.32 10.7 0.0 2.6 2 1 0 2 2 2 0 F-box-like Med16 PF11635.3 ETS63725.1 - 1.1 7.1 4.5 5.1 4.9 3.1 1.9 1 1 0 1 1 1 0 Mediator complex subunit 16 SCF PF02404.10 ETS63727.1 - 0.41 9.8 0.0 0.41 9.8 0.0 3.2 3 1 1 4 4 4 0 Stem cell factor Peptidase_S24 PF00717.18 ETS63728.1 - 2.9e-09 36.4 0.2 9.6e-08 31.5 0.0 2.1 1 1 1 2 2 2 2 Peptidase S24-like Rad60-SLD PF11976.3 ETS63729.1 - 9.4e-07 28.4 0.0 2.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Nop14 PF04147.7 ETS63729.1 - 0.061 11.2 1.5 0.095 10.6 1.0 1.3 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.3 ETS63729.1 - 4.9 7.8 17.5 12 6.6 6.0 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal bZIP_1 PF00170.16 ETS63730.1 - 7.3e-05 22.6 3.2 7.3e-05 22.6 2.2 1.9 3 0 0 3 3 3 1 bZIP transcription factor HeH PF12949.2 ETS63730.1 - 0.0092 15.5 0.2 0.019 14.4 0.2 1.6 1 0 0 1 1 1 1 HeH/LEM domain bZIP_2 PF07716.10 ETS63730.1 - 0.012 15.3 3.0 0.012 15.3 2.1 2.2 3 0 0 3 3 3 0 Basic region leucine zipper PGM_PMM_I PF02878.11 ETS63731.1 - 4.5e-37 126.6 0.2 6.7e-37 126.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 ETS63731.1 - 1.1e-26 93.0 0.0 1.8e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 ETS63731.1 - 5.6e-16 58.7 0.0 1.2e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 ETS63731.1 - 2.7e-09 36.9 0.0 6.1e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3492 PF11997.3 ETS63732.1 - 0.18 11.3 3.3 0.36 10.3 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Na_trans_assoc PF06512.8 ETS63732.1 - 2.1 8.2 9.2 4 7.3 6.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Homeobox_KN PF05920.6 ETS63733.1 - 6.1e-18 64.2 0.3 1.7e-17 62.7 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 ETS63733.1 - 1.6e-05 24.4 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain PX PF00787.19 ETS63735.1 - 6.2e-16 58.2 0.1 2.2e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 PX domain NYD-SP28 PF14772.1 ETS63735.1 - 0.011 15.7 0.2 0.029 14.4 0.2 1.6 1 0 0 1 1 1 0 Sperm tail TelA PF05816.6 ETS63735.1 - 0.044 12.4 2.8 0.031 12.9 0.5 1.7 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) TFIIB PF00382.14 ETS63736.1 - 1.4e-31 108.0 0.4 4.2e-16 58.4 0.0 3.2 2 1 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ETS63736.1 - 1.7e-09 36.8 0.7 3.2e-09 35.9 0.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 ETS63736.1 - 8.5e-05 22.1 0.1 0.12 11.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 ETS63736.1 - 0.0014 17.7 0.7 0.0027 16.8 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 ETS63736.1 - 0.34 10.4 2.5 1.1 8.8 1.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Mob1_phocein PF03637.12 ETS63737.1 - 1.4e-22 80.2 0.1 2.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family DUF202 PF02656.10 ETS63738.1 - 2.4e-21 75.7 3.4 9.3e-21 73.8 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF202) CsbD PF05532.7 ETS63739.1 - 4.8e-21 74.1 19.6 6.6e-12 44.9 5.4 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 ETS63739.1 - 0.0001 22.3 0.8 0.00021 21.2 0.3 1.7 1 1 1 2 2 2 1 Heat shock protein 9/12 MucBP PF06458.7 ETS63739.1 - 0.03 14.9 2.7 0.037 14.6 1.9 1.1 1 0 0 1 1 1 0 MucBP domain cobW PF02492.14 ETS63740.1 - 1.8e-49 167.5 4.3 5.1e-46 156.3 2.9 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.18 ETS63740.1 - 3.6e-24 85.1 0.2 1.4e-23 83.2 0.1 2.1 2 0 0 2 2 2 1 HIT domain CobW_C PF07683.9 ETS63740.1 - 3.6e-18 65.0 0.7 1.9e-13 49.9 0.1 2.9 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.3 ETS63740.1 - 6.6e-05 23.1 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ArgK PF03308.11 ETS63740.1 - 0.00018 20.3 0.1 0.042 12.6 0.0 2.7 2 0 0 2 2 2 2 ArgK protein CwfJ_C_1 PF04677.10 ETS63740.1 - 0.002 17.7 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MobB PF03205.9 ETS63740.1 - 0.0093 15.6 0.1 0.029 14.0 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 ETS63740.1 - 0.026 13.9 0.0 8 5.8 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 ETS63740.1 - 0.027 14.4 1.0 0.83 9.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain UPF0079 PF02367.12 ETS63740.1 - 0.028 14.0 0.1 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 ETS63740.1 - 0.11 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cupin_8 PF13621.1 ETS63741.1 - 7.9e-56 189.3 0.0 1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain FoP_duplication PF13865.1 ETS63743.1 - 2.6 8.5 10.4 6.5 7.2 7.2 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 API5 PF05918.6 ETS63743.1 - 3.4 6.0 12.3 6.1 5.2 8.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) C1_1 PF00130.17 ETS63744.1 - 0.2 11.4 4.8 0.42 10.3 3.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CCHC PF00098.18 ETS63744.1 - 0.4 10.7 2.7 0.26 11.2 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle FHA PF00498.21 ETS63745.1 - 4e-08 33.2 0.0 1.2e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 FHA domain RVT_1 PF00078.22 ETS63745.1 - 0.056 12.7 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TFIID-18kDa PF02269.11 ETS63746.1 - 7.6e-14 51.3 0.1 6.1e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit RPAP1_C PF08620.5 ETS63747.1 - 5.3e-24 83.8 0.1 1.3e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 ETS63747.1 - 0.00051 19.5 0.5 0.0014 18.2 0.4 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 ETS63747.1 - 0.0059 16.5 0.1 2.2 8.5 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat ETC_C1_NDUFA4 PF04800.7 ETS63748.1 - 1.9e-34 117.5 0.1 2.9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Proteasome PF00227.21 ETS63749.1 - 4.8e-41 140.1 0.0 5.5e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AAA PF00004.24 ETS63750.1 - 8.9e-40 135.9 0.0 1.9e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS63750.1 - 7.5e-07 28.4 0.0 1.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETS63750.1 - 2.5e-06 27.6 0.2 0.00011 22.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS63750.1 - 1.1e-05 25.5 0.2 0.00091 19.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETS63750.1 - 1.1e-05 26.1 0.0 2.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS63750.1 - 1.3e-05 24.9 0.1 6.8e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS63750.1 - 5.5e-05 23.0 0.0 9.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS63750.1 - 8.2e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETS63750.1 - 0.00016 21.6 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 ETS63750.1 - 0.00027 20.3 1.0 0.013 14.8 0.3 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETS63750.1 - 0.00035 20.0 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 ETS63750.1 - 0.00068 18.8 0.3 0.0021 17.2 0.2 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 ETS63750.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 ETS63750.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 ETS63750.1 - 0.0015 18.1 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 ETS63750.1 - 0.0019 17.0 0.0 0.0032 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 ETS63750.1 - 0.0028 17.7 0.0 0.0075 16.4 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 ETS63750.1 - 0.003 17.5 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS63750.1 - 0.003 16.6 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 ETS63750.1 - 0.0049 16.5 0.3 0.016 14.9 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_21 PF13304.1 ETS63750.1 - 0.008 16.1 0.4 0.91 9.4 0.1 2.3 1 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 ETS63750.1 - 0.01 15.2 0.0 0.032 13.7 0.0 1.8 1 1 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 ETS63750.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 ETS63750.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 1 0 1 1 1 0 Bacterial dnaA protein Guanylate_kin PF00625.16 ETS63750.1 - 0.017 14.6 0.0 0.051 13.0 0.0 1.8 3 0 0 3 3 1 0 Guanylate kinase KaiC PF06745.8 ETS63750.1 - 0.019 14.0 0.0 0.32 10.0 0.0 2.2 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 ETS63750.1 - 0.02 14.5 0.1 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.8 ETS63750.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 ETS63750.1 - 0.054 13.0 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 ETS63750.1 - 0.064 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IPT PF01745.11 ETS63750.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase UPF0079 PF02367.12 ETS63750.1 - 0.093 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 ETS63750.1 - 0.095 11.9 0.3 0.21 10.7 0.2 1.5 1 1 0 1 1 1 0 PhoH-like protein CPT PF07931.7 ETS63750.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 ETS63750.1 - 0.11 12.1 0.0 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 ETS63750.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP-synt_C PF00137.16 ETS63752.1 - 1.5e-29 101.7 30.3 6.8e-18 64.3 8.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Med6 PF04934.9 ETS63753.1 - 2.1e-47 160.1 0.0 2.7e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component BRO1 PF03097.13 ETS63755.1 - 3.4e-114 381.4 0.6 3.4e-114 381.4 0.4 2.7 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 ETS63755.1 - 1e-61 208.5 13.5 1e-61 208.5 9.4 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV START PF01852.14 ETS63756.1 - 5.2e-05 22.6 0.0 0.00012 21.4 0.0 1.7 1 1 0 1 1 1 1 START domain TPPII PF12580.3 ETS63757.1 - 2.9e-55 186.5 0.2 6.8e-55 185.4 0.1 1.6 1 0 0 1 1 1 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.17 ETS63757.1 - 2e-48 165.0 0.2 4.4e-48 163.8 0.2 1.6 1 0 0 1 1 1 1 Subtilase family Glycos_transf_3 PF00591.16 ETS63758.1 - 1.7e-76 256.9 0.0 1e-70 238.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain TarH PF02203.10 ETS63758.1 - 0.03 14.1 1.0 0.051 13.4 0.7 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue ETF PF01012.16 ETS63759.1 - 5.7e-37 126.9 0.1 7.5e-37 126.5 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Usp PF00582.21 ETS63759.1 - 0.11 12.6 1.7 0.15 12.2 0.5 1.7 2 0 0 2 2 2 0 Universal stress protein family EF-hand_1 PF00036.27 ETS63760.1 - 1e-26 90.1 8.6 3.1e-08 32.3 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 ETS63760.1 - 1.3e-23 82.8 4.3 3.1e-14 52.8 0.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETS63760.1 - 8.1e-22 75.1 2.6 3.3e-06 26.5 0.1 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 ETS63760.1 - 7.7e-15 54.2 6.3 0.00047 19.7 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETS63760.1 - 8.1e-14 50.2 9.5 0.00019 20.6 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 ETS63760.1 - 2.1e-10 40.2 2.9 0.0053 16.4 0.0 4.0 2 1 2 4 4 4 4 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETS63760.1 - 5.1e-05 23.0 1.4 0.016 15.1 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 ETS63760.1 - 0.00033 20.6 1.8 0.33 10.9 0.0 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 ETS63760.1 - 0.023 14.3 1.4 26 4.5 0.0 3.9 4 0 0 4 4 4 0 EF hand EF-hand_2 PF09068.6 ETS63760.1 - 0.024 14.6 0.1 1.4 8.9 0.0 2.8 3 1 0 3 3 3 0 EF hand DUF1679 PF07914.6 ETS63760.1 - 0.041 12.5 0.5 0.8 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mad3_BUB1_II PF08171.6 ETS63760.1 - 0.073 12.9 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 S10_plectin PF03501.10 ETS63760.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_3 PF09069.6 ETS63760.1 - 0.14 12.2 0.1 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 EF-hand zf-C3HC4_3 PF13920.1 ETS63761.1 - 8.2e-09 35.0 3.6 8.3e-07 28.5 0.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS63761.1 - 4.5e-08 32.7 3.7 4.8e-07 29.4 0.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS63761.1 - 1.7e-07 31.1 1.4 1.7e-07 31.1 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS63761.1 - 2.6e-07 30.1 0.4 2.6e-07 30.1 0.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS63761.1 - 3.6e-05 23.3 5.9 4.2e-05 23.1 0.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS63761.1 - 0.0019 17.8 0.5 0.0019 17.8 0.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETS63761.1 - 0.0025 17.6 2.3 0.0025 17.6 1.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING NOT2_3_5 PF04153.13 ETS63763.1 - 2.5e-38 131.0 2.3 2.5e-38 131.0 1.6 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family ArfGap PF01412.13 ETS63764.1 - 1.5e-32 111.8 0.1 1.5e-32 111.8 0.1 2.0 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf A2L_zn_ribbon PF08792.5 ETS63764.1 - 0.017 14.5 1.0 0.035 13.5 0.7 1.5 1 1 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 ETS63764.1 - 0.15 11.9 0.3 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon MAP7 PF05672.6 ETS63764.1 - 2.5 7.4 20.7 0.13 11.6 9.4 2.4 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family UQ_con PF00179.21 ETS63765.1 - 8.4e-42 141.9 0.0 1.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 ETS63765.1 - 1.3e-23 82.3 1.3 2.3e-23 81.5 0.9 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 ETS63765.1 - 0.00061 19.5 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Prok-E2_E PF14462.1 ETS63765.1 - 0.071 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E ATP_bind_1 PF03029.12 ETS63766.1 - 6e-64 215.8 0.0 6.3e-55 186.3 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 ETS63766.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 ETS63766.1 - 0.093 12.2 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS63766.1 - 0.13 13.1 5.1 0.092 13.5 1.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS63766.1 - 0.14 11.9 0.1 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DNA_pol_delta_4 PF04081.8 ETS63767.1 - 3.9e-19 69.1 0.2 5.1e-19 68.7 0.1 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Zn_clus PF00172.13 ETS63769.1 - 2.7e-06 27.1 9.5 2.7e-06 27.1 6.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS63769.1 - 6.4e-05 21.9 0.2 0.00092 18.1 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 ETS63771.1 - 4.8e-29 101.2 29.5 7.3e-27 94.0 20.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS63771.1 - 1.4e-28 99.6 49.7 2.1e-25 89.2 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF106 PF01956.11 ETS63771.1 - 4.6 6.7 6.5 0.94 8.9 0.7 2.2 1 1 1 2 2 2 0 Integral membrane protein DUF106 Fungal_trans PF04082.13 ETS63772.1 - 7.4e-27 93.8 0.0 1.7e-26 92.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS63772.1 - 1e-09 38.1 6.2 1e-09 38.1 4.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NYD-SP28_assoc PF14775.1 ETS63772.1 - 0.35 10.5 1.6 0.9 9.2 0.5 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain CUE PF02845.11 ETS63773.1 - 1.7e-12 46.5 0.0 2.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Sec6 PF06046.8 ETS63773.1 - 0.0058 14.7 0.0 0.0082 14.2 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 WD40 PF00400.27 ETS63774.1 - 3.8e-24 83.6 16.0 1.8e-08 33.9 0.4 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETS63774.1 - 0.0014 17.0 0.1 0.045 12.0 0.0 2.8 4 0 0 4 4 4 1 Cytochrome D1 heme domain Lgl_C PF08596.5 ETS63774.1 - 0.02 13.3 0.1 0.037 12.4 0.1 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Ni_hydr_CYTB PF01292.15 ETS63775.1 - 0.01 15.2 0.6 0.016 14.5 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 NYN PF01936.13 ETS63777.1 - 2.6e-26 92.6 0.0 6.2e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 NYN domain SLH PF00395.15 ETS63777.1 - 0.12 12.1 3.1 4 7.2 0.0 3.4 3 0 0 3 3 3 0 S-layer homology domain Cupin_5 PF06172.6 ETS63778.1 - 1.9e-18 66.7 0.0 2.6e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) EphA2_TM PF14575.1 ETS63780.1 - 0.11 12.9 0.2 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mito_carr PF00153.22 ETS63782.1 - 1.4e-16 59.9 4.1 9.2e-06 25.2 0.0 6.0 5 1 0 5 5 5 5 Mitochondrial carrier protein DUF2390 PF09523.5 ETS63782.1 - 0.095 12.8 0.4 0.24 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Casein_kappa PF00997.13 ETS63783.1 - 0.88 9.2 4.8 2.1 8.0 3.3 1.6 1 1 0 1 1 1 0 Kappa casein Sec7_N PF12783.2 ETS63784.1 - 6.1e-34 116.8 0.6 1.8e-33 115.3 0.4 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 ETS63784.1 - 0.0013 18.1 0.8 0.051 13.0 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF1981) DUF3584 PF12128.3 ETS63785.1 - 0.017 12.4 35.4 0.0028 15.1 22.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 ETS63785.1 - 0.14 11.2 13.0 0.028 13.6 2.7 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 ETS63785.1 - 0.86 9.3 47.5 2.2 8.0 16.6 3.9 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 ETS63785.1 - 1.7 8.4 49.5 6.3 6.6 9.0 3.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 ETS63785.1 - 2.4 8.2 42.7 29 4.7 3.4 4.4 2 1 1 3 3 3 0 DivIVA protein DUF4201 PF13870.1 ETS63785.1 - 3.6 6.9 40.3 1 8.7 10.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) ERM PF00769.14 ETS63785.1 - 9.9 5.6 54.7 0.36 10.3 14.6 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cu-oxidase_4 PF02578.10 ETS63786.1 - 0.02 13.9 0.3 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase zf-rbx1 PF12678.2 ETS63787.1 - 5.6e-14 52.0 0.9 9.5e-14 51.2 0.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 ETS63787.1 - 2.5e-11 43.1 6.9 7.5e-11 41.6 4.8 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS63787.1 - 1.9e-06 27.4 3.2 3.6e-06 26.5 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS63787.1 - 3e-06 26.8 2.2 6.6e-06 25.7 1.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS63787.1 - 9.3e-06 25.5 2.0 9.3e-06 25.5 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS63787.1 - 2.3e-05 24.1 0.2 5.1e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 ETS63787.1 - 2.8e-05 23.6 5.4 0.00049 19.7 4.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS63787.1 - 0.00031 20.3 2.1 0.00076 19.1 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETS63787.1 - 0.0018 18.1 2.5 0.0028 17.5 1.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 ETS63787.1 - 0.0057 16.5 0.4 0.012 15.5 0.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 ETS63787.1 - 0.66 9.6 2.4 0.97 9.0 0.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SET PF00856.23 ETS63788.1 - 1.7e-07 31.6 0.0 1.7e-07 31.6 0.0 3.5 4 0 0 4 4 4 1 SET domain DUF2076 PF09849.4 ETS63790.1 - 2.8e-09 37.4 11.0 3.3e-09 37.1 7.6 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 ETS63790.1 - 0.001 18.9 5.9 0.0018 18.1 4.1 1.4 1 0 0 1 1 1 1 CHCH domain Nucleoporin_FG PF13634.1 ETS63790.1 - 0.42 10.8 15.3 0.91 9.7 10.6 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region PAT1 PF09770.4 ETS63790.1 - 5.1 5.1 9.5 6.2 4.9 6.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 ETS63790.1 - 6.7 6.7 12.8 0.17 11.9 2.0 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA PF00004.24 ETS63791.1 - 1.2e-44 151.6 0.1 3.7e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS63791.1 - 8.4e-09 35.2 0.5 2.7e-08 33.6 0.1 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETS63791.1 - 6.7e-08 32.6 0.0 1.6e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETS63791.1 - 4.3e-07 30.1 0.5 0.00033 20.7 0.3 3.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS63791.1 - 8.7e-07 29.1 0.1 3.9e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 ETS63791.1 - 4e-06 25.9 0.1 1.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 ETS63791.1 - 0.0002 21.3 0.4 0.00081 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS63791.1 - 0.00038 19.5 0.0 0.00089 18.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 ETS63791.1 - 0.00042 20.0 0.2 0.0029 17.3 0.0 2.4 3 0 0 3 3 2 1 NTPase AAA_19 PF13245.1 ETS63791.1 - 0.00046 19.8 0.1 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 ETS63791.1 - 0.00054 19.8 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 ETS63791.1 - 0.00065 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS63791.1 - 0.00077 19.7 0.2 0.015 15.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 ETS63791.1 - 0.00096 18.8 0.1 0.034 13.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 ETS63791.1 - 0.0011 19.7 0.0 0.0049 17.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 ETS63791.1 - 0.0014 17.3 0.0 0.0028 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 ETS63791.1 - 0.0018 18.4 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Arch_ATPase PF01637.13 ETS63791.1 - 0.0027 17.4 0.7 0.09 12.4 0.0 3.0 2 1 0 3 3 3 1 Archaeal ATPase AAA_33 PF13671.1 ETS63791.1 - 0.0035 17.2 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 ETS63791.1 - 0.0057 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETS63791.1 - 0.0059 16.2 0.0 0.02 14.5 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 ETS63791.1 - 0.0059 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 ETS63791.1 - 0.0064 16.0 1.6 0.025 14.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS63791.1 - 0.0075 15.3 0.4 0.015 14.4 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin IstB_IS21 PF01695.12 ETS63791.1 - 0.0082 15.5 0.3 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 ETS63791.1 - 0.013 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETS63791.1 - 0.018 15.3 3.2 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 ETS63791.1 - 0.022 14.3 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 1 0 Bacterial dnaA protein AAA_25 PF13481.1 ETS63791.1 - 0.049 13.0 0.1 0.049 13.0 0.1 2.6 2 1 1 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 ETS63791.1 - 0.053 13.5 0.2 0.97 9.4 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 ETS63791.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.11 ETS63791.1 - 0.058 12.1 0.2 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.21 ETS63791.1 - 0.064 12.7 0.2 1.4 8.3 0.0 2.8 3 1 0 3 3 3 0 Sigma-54 interaction domain KaiC PF06745.8 ETS63791.1 - 0.12 11.4 0.6 0.53 9.3 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_29 PF13555.1 ETS63791.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2968 PF11180.3 ETS63791.1 - 0.5 9.7 5.9 0.96 8.8 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_10 PF12846.2 ETS63791.1 - 1.2 8.5 3.6 1.4 8.2 0.1 2.6 3 1 1 4 4 4 0 AAA-like domain P5CR_dimer PF14748.1 ETS63792.1 - 6e-38 129.1 2.7 6e-38 129.1 1.9 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 ETS63792.1 - 1.6e-13 50.9 0.7 5.3e-12 46.0 0.5 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GDA1_CD39 PF01150.12 ETS63793.1 - 8.3e-85 284.8 0.0 1.2e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 ETS63793.1 - 0.19 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family NAD_kinase PF01513.16 ETS63794.1 - 3.4e-67 226.2 0.0 7.8e-67 225.0 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase zf-C2H2 PF00096.21 ETS63796.1 - 7.1e-09 35.5 14.8 0.0003 20.9 2.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS63796.1 - 0.0021 18.2 11.9 0.0037 17.4 0.9 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETS63796.1 - 0.031 14.1 3.2 1.1 9.2 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETS63796.1 - 0.04 14.2 11.8 0.31 11.4 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 ETS63796.1 - 6 6.6 7.3 5 6.9 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sec7 PF01369.15 ETS63797.1 - 1.6e-37 129.0 0.0 3.6e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 ETS63797.1 - 5.5e-30 103.9 0.0 1.3e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETS63797.1 - 0.00025 21.2 0.0 0.00062 19.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Sec2p PF06428.6 ETS63798.1 - 1.5e-15 56.8 9.3 1.5e-15 56.8 6.4 3.1 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF948 PF06103.6 ETS63798.1 - 0.078 12.8 3.8 6.7 6.6 0.2 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NAD_Gly3P_dh_C PF07479.9 ETS63800.1 - 1.6e-50 170.6 0.0 2.7e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 ETS63800.1 - 1.9e-49 167.4 0.1 3.4e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 ETS63800.1 - 0.00014 22.2 0.3 0.0024 18.2 0.2 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RCC1 PF00415.13 ETS63801.1 - 8.5e-34 115.5 15.9 6e-06 26.3 0.1 8.1 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS63801.1 - 4.5e-28 96.2 17.4 1.7e-06 27.4 0.1 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_38 PF01074.17 ETS63802.1 - 5.3e-83 278.4 1.4 8.2e-83 277.8 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 ETS63802.1 - 3.3e-54 184.4 0.0 4.8e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 ETS63802.1 - 8.4e-27 93.2 0.2 2.1e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Con-6 PF10346.4 ETS63802.1 - 8.3e-07 28.3 0.1 1.6e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Tannase PF07519.6 ETS63803.1 - 3e-77 260.3 0.3 2.4e-76 257.3 0.2 2.2 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 ETS63803.1 - 7e-06 25.8 0.0 0.0091 15.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS63803.1 - 0.00024 20.3 0.0 0.068 12.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS63803.1 - 0.0011 18.9 0.0 0.0092 15.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS63803.1 - 0.039 13.3 0.1 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.15 ETS63803.1 - 0.68 9.4 5.1 2.2 7.7 3.6 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 ETS63805.1 - 3.9e-60 203.2 0.0 5.1e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63805.1 - 3.1e-24 85.4 0.0 4.4e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS63805.1 - 3.6e-05 22.8 0.0 6.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS63805.1 - 0.016 14.9 0.0 0.067 12.9 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS63805.1 - 0.053 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RabGAP-TBC PF00566.13 ETS63806.1 - 4.5e-36 124.3 0.0 6.4e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-RING_5 PF14634.1 ETS63806.1 - 0.0074 15.9 0.0 0.0074 15.9 0.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETS63806.1 - 0.008 15.9 0.1 0.008 15.9 0.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 ETS63806.1 - 0.016 14.9 1.0 0.03 14.0 0.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_L30 PF00327.15 ETS63807.1 - 6.8e-12 44.7 0.1 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Drc1-Sld2 PF11719.3 ETS63809.1 - 4.6e-07 29.2 22.2 4.6e-07 29.2 15.4 2.9 2 1 0 2 2 2 1 DNA replication and checkpoint protein SAGA-Tad1 PF12767.2 ETS63809.1 - 3.6 7.1 7.5 0.5 9.9 1.9 1.9 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit NAD_binding_6 PF08030.7 ETS63810.1 - 0.0002 21.3 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETS63810.1 - 0.002 18.6 0.0 0.006 17.1 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS63810.1 - 0.0026 17.8 0.0 0.1 12.7 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain Pkinase PF00069.20 ETS63811.1 - 3.3e-39 134.5 0.0 4.2e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63811.1 - 6.3e-16 58.2 0.0 8.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS63811.1 - 5.2e-06 26.3 0.1 0.003 17.3 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETS63811.1 - 0.018 13.8 0.1 0.032 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PFU PF09070.6 ETS63811.1 - 0.089 12.8 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) PCI PF01399.22 ETS63812.1 - 5.2e-16 58.8 0.0 2.2e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain DUF1510 PF07423.6 ETS63812.1 - 0.003 16.9 6.4 0.0053 16.1 4.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 ETS63812.1 - 0.014 14.8 11.5 0.032 13.6 8.0 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 ETS63812.1 - 0.028 12.1 5.4 0.041 11.5 3.8 1.2 1 0 0 1 1 1 0 Ycf1 Cnd1_N PF12922.2 ETS63812.1 - 0.055 13.1 3.8 6.7 6.3 0.0 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term RNase_H2-Ydr279 PF09468.5 ETS63812.1 - 0.27 10.4 6.8 0.49 9.5 4.7 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Sigma70_ner PF04546.8 ETS63812.1 - 0.42 10.2 18.6 1.3 8.5 10.2 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Vfa1 PF08432.5 ETS63812.1 - 2 8.4 17.5 0.23 11.4 8.7 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 ETS63812.1 - 2.3 7.1 12.9 6.3 5.7 9.0 1.7 1 0 0 1 1 1 0 Autophagy protein Apg6 SPATIAL PF15256.1 ETS63812.1 - 7.5 6.5 10.3 7.4 6.5 5.8 2.0 1 1 1 2 2 2 0 SPATIAL ANTH PF07651.11 ETS63813.1 - 3.4e-75 252.3 0.2 3.4e-75 252.3 0.2 2.4 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 ETS63813.1 - 1.1e-62 210.4 8.7 1.1e-62 210.4 6.0 4.4 4 1 0 4 4 4 2 I/LWEQ domain ENTH PF01417.15 ETS63813.1 - 1.5e-09 37.8 0.3 1.6e-08 34.4 0.0 2.9 2 0 0 2 2 2 1 ENTH domain TcdB_N PF12918.2 ETS63813.1 - 0.025 14.6 0.1 0.088 12.9 0.0 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain ATP-synt_ab PF00006.20 ETS63813.1 - 0.073 12.5 0.8 0.16 11.4 0.6 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SUR7 PF06687.7 ETS63814.1 - 3.5e-26 92.0 10.0 4.6e-26 91.7 6.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family MMPL PF03176.10 ETS63814.1 - 0.25 10.0 3.1 0.46 9.1 2.1 1.3 1 0 0 1 1 1 0 MMPL family Claudin_2 PF13903.1 ETS63814.1 - 0.26 10.9 11.2 0.5 10.0 7.4 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction VMA21 PF09446.5 ETS63814.1 - 0.34 10.8 2.1 0.72 9.8 1.5 1.4 1 0 0 1 1 1 0 VMA21-like domain Clc-like PF07062.7 ETS63814.1 - 4.9 6.3 6.5 9.7 5.3 4.5 1.5 1 0 0 1 1 1 0 Clc-like Ion_trans PF00520.26 ETS63815.1 - 9.3e-05 21.7 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Ion transport protein Homeobox PF00046.24 ETS63816.1 - 5.4e-13 48.3 0.2 1.3e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 ETS63816.1 - 0.00026 20.6 0.3 0.00077 19.1 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain Ustilago_mating PF05722.7 ETS63817.1 - 2.3e-94 315.9 4.7 3.1e-94 315.4 3.3 1.2 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Homeobox_KN PF05920.6 ETS63817.1 - 2.2e-15 56.0 2.2 9.1e-15 54.0 1.5 2.1 1 1 0 1 1 1 1 Homeobox KN domain Sas10_Utp3 PF04000.10 ETS63818.1 - 1.5e-22 79.5 0.1 3.8e-22 78.2 0.1 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ydc2-catalyt PF09159.5 ETS63818.1 - 0.13 11.7 4.1 0.28 10.6 2.8 1.5 1 1 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 HA2 PF04408.18 ETS63820.1 - 9.3e-19 67.3 2.8 1.2e-18 66.9 0.1 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS63820.1 - 2.8e-13 49.5 0.1 8.5e-13 47.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 ETS63820.1 - 1.4e-10 41.0 0.0 3.9e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 ETS63820.1 - 2.1e-10 40.3 0.0 4.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS63820.1 - 7e-08 32.6 0.3 3e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETS63820.1 - 0.044 12.6 0.0 0.091 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 ETS63820.1 - 0.044 12.8 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 ETS63820.1 - 0.085 13.1 0.0 0.085 13.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF883 PF05957.8 ETS63822.1 - 5.3e-07 29.9 36.7 0.014 15.7 2.5 4.3 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) AF0941-like PF14591.1 ETS63822.1 - 0.034 14.2 0.4 0.18 11.8 0.0 2.1 2 1 1 3 3 3 0 AF0941-like Apolipoprotein PF01442.13 ETS63822.1 - 0.076 12.5 20.6 0.57 9.6 1.6 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 ETS63822.1 - 0.11 12.9 32.7 0.3 11.4 1.7 4.7 1 1 1 2 2 2 0 YtxH-like protein DivIVA PF05103.8 ETS63822.1 - 0.6 10.1 43.0 0.068 13.2 5.8 4.6 1 1 4 5 5 5 0 DivIVA protein ApoO PF09769.4 ETS63822.1 - 0.93 9.1 6.0 0.55 9.9 0.5 2.5 3 0 0 3 3 3 0 Apolipoprotein O ATP-synt_B PF00430.13 ETS63822.1 - 3.2 7.5 52.8 1.6 8.5 6.8 3.8 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) CS PF04969.11 ETS63823.1 - 0.003 18.0 0.0 0.024 15.1 0.0 2.2 2 0 0 2 2 2 1 CS domain SNF2_N PF00176.18 ETS63824.1 - 1e-64 218.2 0.0 1.6e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 ETS63824.1 - 6.1e-14 51.8 0.0 1.7e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 ETS63824.1 - 2.7e-08 33.5 0.0 6.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 ETS63824.1 - 0.00045 19.8 0.5 0.00045 19.8 0.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS63824.1 - 0.00073 19.1 0.5 0.002 17.7 0.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS63824.1 - 0.0022 17.8 1.5 0.0052 16.5 1.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS63824.1 - 0.0024 17.8 1.2 0.0059 16.6 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 ETS63824.1 - 0.12 12.2 1.1 18 5.2 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon PNP_UDP_1 PF01048.15 ETS63825.1 - 2.7e-36 124.7 0.4 3.3e-36 124.4 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily MMR_HSR1 PF01926.18 ETS63826.1 - 1.8e-14 53.6 0.0 1.8e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS63826.1 - 9.6e-05 21.7 0.0 0.00055 19.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETS63826.1 - 0.0014 18.4 0.1 0.007 16.1 0.1 2.1 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 ETS63826.1 - 0.014 15.8 0.0 0.043 14.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 ETS63826.1 - 0.035 13.2 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 ETS63826.1 - 0.19 10.7 0.0 0.45 9.4 0.0 1.7 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 ETS63826.1 - 0.21 11.0 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NIF PF03031.13 ETS63827.1 - 6.3e-22 77.9 0.0 2.3e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 ETS63827.1 - 0.0044 17.2 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PTCB-BRCT PF12738.2 ETS63827.1 - 0.0058 16.4 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain DPBB_1 PF03330.13 ETS63828.1 - 4.5e-06 26.5 1.1 1.3e-05 25.0 0.8 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 ETS63828.1 - 0.0014 18.3 0.2 0.0024 17.5 0.1 1.6 1 1 0 1 1 1 1 Barwin family DUF2217 PF10265.4 ETS63828.1 - 0.036 12.8 5.5 0.057 12.1 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) TIM-br_sig_trns PF09370.5 ETS63828.1 - 0.14 11.2 0.3 0.21 10.6 0.2 1.2 1 0 0 1 1 1 0 TIM-barrel signal transduction protein Sporozoite_P67 PF05642.6 ETS63828.1 - 2.5 5.8 10.9 2.6 5.7 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 ETS63828.1 - 2.7 7.7 20.7 0.075 12.8 9.8 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein PIP5K PF01504.13 ETS63829.1 - 4.4e-63 212.7 0.0 8.5e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 ETS63829.1 - 4.1e-22 78.4 0.0 6.3e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 ETS63829.1 - 1.7e-15 56.6 10.3 4.3e-15 55.3 7.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 ETS63829.1 - 0.074 12.9 3.4 0.24 11.3 2.4 1.8 1 0 0 1 1 1 0 IBR domain Nop53 PF07767.6 ETS63829.1 - 4.9 6.0 13.1 9.4 5.1 9.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TRAP_alpha PF03896.11 ETS63829.1 - 7.7 5.4 7.6 20 4.0 5.2 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cpn60_TCP1 PF00118.19 ETS63830.1 - 6.9e-148 493.2 0.4 8e-148 493.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family A_deaminase PF00962.17 ETS63831.1 - 2.6e-36 125.2 0.0 4.7e-36 124.3 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Lactamase_B PF00753.22 ETS63832.1 - 1.6e-23 83.3 1.4 2.7e-23 82.6 1.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily LRR_6 PF13516.1 ETS63832.1 - 1.8e-11 42.8 0.9 1.1 9.5 0.0 7.3 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.2 ETS63832.1 - 4.7e-07 29.4 0.1 1.3e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 ETS63832.1 - 1.7e-05 24.2 11.3 7.9 7.1 0.1 7.5 7 0 0 7 7 7 2 Leucine rich repeat LRR_4 PF12799.2 ETS63832.1 - 0.00032 20.2 5.7 2.2 7.9 0.0 5.6 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS63832.1 - 0.00061 19.4 11.6 12 6.4 0.1 6.6 6 1 0 6 6 6 1 Leucine Rich Repeat F-box PF00646.28 ETS63832.1 - 0.0019 17.8 4.9 0.072 12.7 0.5 3.4 2 1 0 2 2 2 1 F-box domain LRR_8 PF13855.1 ETS63832.1 - 0.0026 17.4 2.1 1.5 8.6 0.1 4.1 5 0 0 5 5 5 1 Leucine rich repeat Lactamase_B_2 PF12706.2 ETS63832.1 - 0.015 14.8 0.3 0.03 13.8 0.2 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_S7 PF00177.16 ETS63834.1 - 9.1e-41 138.8 1.0 1.1e-40 138.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e WD40 PF00400.27 ETS63835.1 - 3.5e-63 207.3 17.1 1.5e-10 40.5 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 ETS63835.1 - 1.2e-06 28.0 0.3 2.2e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 ETS63835.1 - 0.00048 19.8 0.0 0.048 13.3 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETS63835.1 - 0.0057 14.8 0.3 0.67 8.0 0.0 3.1 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 ETS63835.1 - 0.027 13.9 0.1 7 6.2 0.0 4.1 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 ETS63835.1 - 0.059 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.7 ETS63835.1 - 0.079 10.7 0.0 0.14 9.9 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Aminotran_1_2 PF00155.16 ETS63836.1 - 4.5e-91 305.4 0.0 5.3e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ABC_tran PF00005.22 ETS63838.1 - 1.6e-35 122.3 0.0 1.9e-34 118.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 ETS63838.1 - 6.1e-33 114.4 6.3 7.6e-33 114.0 4.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 ETS63838.1 - 5.1e-07 29.9 0.0 0.013 15.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 ETS63838.1 - 1.7e-05 24.1 0.1 0.0018 17.5 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 ETS63838.1 - 0.00075 19.7 0.0 0.0071 16.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS63838.1 - 0.0052 16.7 0.0 0.032 14.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 ETS63838.1 - 0.0098 15.4 0.1 0.025 14.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 ETS63838.1 - 0.016 15.1 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 ETS63838.1 - 0.023 14.8 0.0 0.17 11.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS63838.1 - 0.035 13.2 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS63838.1 - 0.052 14.3 0.0 0.15 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 ETS63838.1 - 0.066 13.1 0.2 0.55 10.1 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 ETS63838.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 ETS63839.1 - 0.00057 19.6 0.2 0.0026 17.5 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS63839.1 - 0.0054 16.6 1.0 0.015 15.2 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS63839.1 - 0.15 11.4 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DNA_pol_B_thumb PF14791.1 ETS63840.1 - 1.5e-19 69.4 0.0 3.1e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 ETS63840.1 - 1.8e-08 34.4 0.0 5.2e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 ETS63840.1 - 4.2e-08 33.2 0.1 1.6e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 ETS63840.1 - 0.00015 21.2 0.0 0.00032 20.1 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda SNARE PF05739.14 ETS63841.1 - 1.1e-16 60.1 1.0 1.1e-16 60.1 0.7 2.4 3 0 0 3 3 2 1 SNARE domain Syntaxin PF00804.20 ETS63841.1 - 1.1e-15 57.6 3.9 2.7e-15 56.3 0.3 2.4 2 0 0 2 2 2 1 Syntaxin DUF1664 PF07889.7 ETS63841.1 - 0.028 14.1 2.4 0.18 11.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 ETS63841.1 - 0.035 13.9 1.5 0.11 12.3 0.1 2.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-18_N PF10496.4 ETS63841.1 - 0.036 13.8 0.8 0.3 10.9 0.1 2.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF2894 PF11445.3 ETS63841.1 - 0.085 13.1 4.8 0.094 12.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) Lge1 PF11488.3 ETS63841.1 - 0.1 12.7 1.5 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Syntaxin-6_N PF09177.6 ETS63841.1 - 0.14 12.5 3.5 1.6 9.1 0.1 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF848 PF05852.6 ETS63841.1 - 0.74 9.6 4.7 4.5 7.1 0.1 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Spectrin PF00435.16 ETS63841.1 - 1.1 9.5 4.8 4.4 7.6 0.2 3.3 2 1 0 3 3 3 0 Spectrin repeat AAA_13 PF13166.1 ETS63841.1 - 1.4 7.3 6.8 0.5 8.7 1.4 1.9 2 0 0 2 2 2 0 AAA domain DUF148 PF02520.12 ETS63841.1 - 2.3 8.0 7.5 0.82 9.4 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function DUF148 BLOC1_2 PF10046.4 ETS63841.1 - 2.7 8.2 7.2 2.6 8.2 0.4 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 ETS63841.1 - 4.2 7.1 9.9 1 9.1 0.1 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) RRM_1 PF00076.17 ETS63842.1 - 5.7e-15 54.7 0.0 4.4e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS63842.1 - 1.4e-12 47.3 0.0 2.7e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS63842.1 - 1.1e-06 28.3 0.1 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.3 ETS63842.1 - 0.1 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Pkinase PF00069.20 ETS63843.1 - 1.3e-66 224.4 0.0 1.6e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63843.1 - 1.2e-28 99.9 0.0 1.7e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETS63843.1 - 5.3e-11 42.8 0.1 5.3e-11 42.8 0.1 3.3 3 1 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETS63843.1 - 4e-08 32.5 0.0 1.8e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 ETS63843.1 - 9.7e-05 22.1 0.0 0.00039 20.2 0.0 2.0 1 1 0 1 1 1 1 C2 domain APH PF01636.18 ETS63843.1 - 0.04 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 ETS63843.1 - 0.16 11.0 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_67N PF03648.9 ETS63844.1 - 0.1 12.6 0.1 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus DUF896 PF05979.7 ETS63844.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) SGS PF05002.10 ETS63845.1 - 9.3e-27 92.6 0.4 2e-26 91.5 0.3 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.11 ETS63845.1 - 3.5e-15 56.3 0.0 4.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 CS domain DUF2057 PF09829.4 ETS63845.1 - 0.011 15.4 1.9 0.011 15.4 1.3 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Alg6_Alg8 PF03155.10 ETS63846.1 - 3.1e-120 402.2 22.9 1.6e-117 393.2 12.9 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family PUF PF00806.14 ETS63847.1 - 7e-59 192.1 0.0 6.5e-08 31.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 ETS63847.1 - 0.014 15.6 0.4 6.2 7.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF260 FliG_C PF01706.11 ETS63847.1 - 0.099 12.6 0.6 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 FliG C-terminal domain Phosducin PF02114.11 ETS63848.1 - 6.8e-13 47.9 0.0 2.6e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Phosducin Thioredoxin PF00085.15 ETS63848.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin FoP_duplication PF13865.1 ETS63848.1 - 0.3 11.5 7.5 0.14 12.6 1.5 2.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 GOLD_2 PF13897.1 ETS63848.1 - 0.78 9.9 2.7 0.8 9.9 0.0 1.9 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking GST_N_3 PF13417.1 ETS63849.1 - 1.7e-08 34.5 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS63849.1 - 2.9e-05 23.9 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS63849.1 - 0.0068 16.3 0.1 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Telomere_Sde2 PF13019.1 ETS63851.1 - 2.7e-36 124.7 0.8 2.7e-36 124.7 0.6 1.6 2 0 0 2 2 2 1 Telomere stability and silencing DUF1116 PF06545.6 ETS63851.1 - 0.0086 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1116) DUF572 PF04502.8 ETS63851.1 - 0.22 10.6 11.1 0.27 10.4 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GTSE1_N PF15259.1 ETS63851.1 - 1.5 8.8 6.9 0.17 11.8 0.7 2.0 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 Lactamase_B_2 PF12706.2 ETS63852.1 - 6.3e-05 22.6 0.1 0.00018 21.1 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 ETS63852.1 - 0.013 15.5 0.1 0.088 12.8 0.1 2.2 1 1 0 1 1 1 0 DNA repair metallo-beta-lactamase zf-RING_2 PF13639.1 ETS63853.1 - 1.5e-07 31.1 5.9 1.5e-07 31.1 4.1 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS63853.1 - 1.8e-06 27.9 1.3 3.7e-06 26.9 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger Nop14 PF04147.7 ETS63853.1 - 0.00021 19.4 0.9 0.00021 19.4 0.6 2.3 2 0 0 2 2 2 1 Nop14-like family zf-Apc11 PF12861.2 ETS63853.1 - 0.0021 17.8 1.6 0.0044 16.8 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 ETS63853.1 - 0.0038 17.1 3.1 0.0098 15.8 2.1 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 ETS63853.1 - 0.011 15.8 5.4 0.026 14.5 3.7 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 ETS63853.1 - 0.016 14.9 0.8 0.031 14.0 0.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 ETS63853.1 - 0.044 13.4 7.6 0.084 12.5 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 ETS63853.1 - 2.7 7.6 4.9 5.2 6.7 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 ETS63853.1 - 6.2 6.9 4.7 12 6.0 3.2 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 ETS63853.1 - 6.6 6.5 4.6 14 5.4 3.2 1.5 1 0 0 1 1 1 0 PHD-finger TFIIS_M PF07500.9 ETS63854.1 - 2.4e-21 75.9 1.0 7e-21 74.4 0.7 1.9 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 ETS63854.1 - 5.8e-15 55.8 0.0 1.6e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 ETS63854.1 - 1.1e-12 47.3 8.2 1.9e-12 46.6 5.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS63854.1 - 0.033 13.4 3.0 0.06 12.6 2.1 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 ETS63854.1 - 0.23 11.7 2.0 0.92 9.7 1.4 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Porin_3 PF01459.17 ETS63855.1 - 3.1e-76 256.2 2.7 3.6e-76 256.0 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Fcf1 PF04900.7 ETS63856.1 - 8.5e-40 134.9 0.6 3.7e-39 132.8 0.3 1.8 2 0 0 2 2 2 1 Fcf1 MRP-L28 PF09812.4 ETS63856.1 - 0.11 12.2 0.3 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Peptidase_M22 PF00814.20 ETS63858.1 - 9.8e-72 241.6 0.3 1.3e-71 241.2 0.2 1.1 1 0 0 1 1 1 1 Glycoprotease family Exo_endo_phos PF03372.18 ETS63859.1 - 2e-15 57.3 0.2 4.4e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETS63859.1 - 1.3e-10 40.9 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 ETS63859.1 - 2.6e-07 30.4 6.2 3.7e-06 26.7 3.7 2.8 1 1 1 2 2 2 1 GRF zinc finger SCA7 PF08313.7 ETS63860.1 - 2.3e-30 103.9 0.5 4.6e-30 103.0 0.4 1.4 1 0 0 1 1 1 1 SCA7, zinc-binding domain DASH_Dad2 PF08654.5 ETS63861.1 - 4.8e-30 103.5 0.0 6e-30 103.2 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF3348 PF11828.3 ETS63861.1 - 0.017 14.5 0.1 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) ATP-synt_ab PF00006.20 ETS63862.1 - 4.9e-110 366.1 0.0 6.8e-110 365.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETS63862.1 - 9.9e-22 77.5 0.2 2.1e-21 76.5 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETS63862.1 - 4e-14 52.5 4.2 6.2e-14 51.9 2.3 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 ETS63864.1 - 6.4e-42 142.8 0.0 2e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS63864.1 - 8.1e-06 26.0 0.0 0.00058 20.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS63864.1 - 1.1e-05 25.2 0.1 5.9e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS63864.1 - 9.9e-05 22.3 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 ETS63864.1 - 0.00019 21.3 0.0 0.00065 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 ETS63864.1 - 0.00098 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 ETS63864.1 - 0.0023 18.7 0.5 0.005 17.6 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 ETS63864.1 - 0.0034 17.0 0.1 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 ETS63864.1 - 0.0041 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 ETS63864.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETS63864.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 ETS63864.1 - 0.015 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS63864.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETS63864.1 - 0.021 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 ETS63864.1 - 0.025 14.2 0.0 6.6 6.3 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 ETS63864.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETS63864.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 ETS63864.1 - 0.043 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 ETS63864.1 - 0.05 12.3 0.0 0.091 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 ETS63864.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETS63864.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 ETS63864.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETS63864.1 - 0.094 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 ETS63864.1 - 0.13 11.6 0.3 0.66 9.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain DUF4187 PF13821.1 ETS63865.1 - 4.1e-17 61.4 6.1 4.1e-17 61.4 4.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 ETS63865.1 - 3e-06 26.9 1.2 7.2e-06 25.6 0.8 1.6 1 0 0 1 1 1 1 G-patch domain CDC45 PF02724.9 ETS63865.1 - 7.5 4.4 11.5 0.69 7.8 1.0 2.8 3 0 0 3 3 3 0 CDC45-like protein CDP-OH_P_transf PF01066.16 ETS63866.1 - 2e-19 69.7 5.3 5.1e-19 68.4 3.7 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ORC3_N PF07034.6 ETS63867.1 - 3.8e-13 49.1 0.1 2.4e-05 23.4 0.0 2.7 3 0 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus DUF2205 PF10224.4 ETS63869.1 - 3.6e-12 45.6 0.3 5.4e-12 45.1 0.2 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) CBM_21 PF03370.8 ETS63873.1 - 5.6e-30 103.6 0.1 9.7e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Serglycin PF04360.7 ETS63873.1 - 0.06 13.0 4.6 0.16 11.7 3.2 1.7 1 0 0 1 1 1 0 Serglycin V_ATPase_I PF01496.14 ETS63875.1 - 3.9e-264 878.1 0.0 4.4e-264 877.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.8 ETS63875.1 - 0.79 9.7 6.2 0.17 11.8 0.4 2.8 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.7 ETS63875.1 - 0.79 10.1 3.1 8.8 6.7 0.6 2.9 3 0 0 3 3 3 0 SlyX VCBS PF13517.1 ETS63876.1 - 9.1e-21 73.9 17.4 1.8e-07 31.3 1.3 6.1 4 1 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RNase_H2-Ydr279 PF09468.5 ETS63876.1 - 9.9e-17 61.0 0.0 1.8e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) FG-GAP PF01839.18 ETS63876.1 - 1.1e-16 59.9 13.7 9.1e-05 22.0 0.1 6.9 6 0 0 6 6 6 6 FG-GAP repeat 2Fe-2S_thioredx PF01257.14 ETS63877.1 - 2.1e-59 199.2 0.1 2.7e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 ETS63877.1 - 0.037 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) HTH_30 PF13556.1 ETS63877.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Mitofilin PF09731.4 ETS63878.1 - 1.4e-147 492.8 22.3 1.6e-147 492.7 15.4 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein EthD PF07110.6 ETS63880.1 - 7.9e-09 36.3 0.2 1e-07 32.7 0.0 2.1 2 0 0 2 2 2 1 EthD domain Peptidase_M20 PF01546.23 ETS63881.1 - 3.6e-23 82.0 0.0 5.3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS63881.1 - 9.6e-14 51.0 0.0 2.6e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Abhydrolase_3 PF07859.8 ETS63882.1 - 2.5e-33 115.4 0.0 1.3e-32 113.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS63882.1 - 3.1e-06 27.2 0.1 8.9e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS63882.1 - 3.7e-05 23.5 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS63882.1 - 0.00012 21.6 0.0 0.012 15.0 0.0 2.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 ETS63882.1 - 0.00027 20.2 0.0 0.0092 15.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETS63882.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 ETS63882.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 ETS63882.1 - 0.091 12.1 0.4 9.2 5.6 0.2 3.4 2 1 0 2 2 2 0 Putative esterase Polysacc_deac_1 PF01522.16 ETS63883.1 - 7.9e-23 80.4 0.0 1.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Nup160 PF11715.3 ETS63884.1 - 7.5e-119 397.3 0.0 1e-118 396.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Apc3 PF12895.2 ETS63884.1 - 0.022 14.9 0.2 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FAD_binding_3 PF01494.14 ETS63885.1 - 7.7e-57 192.9 0.1 1.3e-55 188.9 0.0 2.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS63885.1 - 1.4e-18 67.0 0.0 3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 ETS63885.1 - 5.9e-06 26.2 0.0 1.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS63885.1 - 7.3e-05 21.8 0.0 0.00021 20.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS63885.1 - 8.2e-05 21.2 0.0 0.00013 20.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS63885.1 - 0.00071 18.6 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS63885.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS63885.1 - 0.0017 17.2 0.1 0.0036 16.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS63885.1 - 0.0046 17.0 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS63885.1 - 0.0059 15.7 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 ETS63885.1 - 0.0092 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS63885.1 - 0.03 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS63885.1 - 0.042 13.3 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 ETS63885.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 ETS63885.1 - 0.13 12.2 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 ETS63885.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 ETS63885.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 ETS63885.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Adaptin_binding PF10199.4 ETS63886.1 - 0.046 13.9 0.4 0.046 13.9 0.2 2.9 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 LURAP PF14854.1 ETS63886.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 Leucine rich adaptor protein MitMem_reg PF13012.1 ETS63887.1 - 1.1e-16 60.8 0.7 1.9e-16 60.1 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 ETS63887.1 - 5.1e-15 55.1 0.0 1.3e-13 50.6 0.0 2.3 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CENP-W PF15510.1 ETS63888.1 - 0.0053 16.7 0.3 0.018 15.0 0.2 1.8 1 1 0 1 1 1 1 Centromere kinetochore component W TPR_MLP1_2 PF07926.7 ETS63889.1 - 0.021 14.5 3.1 0.045 13.4 2.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tmemb_cc2 PF10267.4 ETS63889.1 - 6.6 5.2 11.2 0.031 12.8 1.0 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein FAD_binding_6 PF00970.19 ETS63890.1 - 6.4e-32 109.6 0.0 1.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 ETS63890.1 - 5.3e-29 100.9 0.0 8.5e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETS63890.1 - 5.2e-09 36.2 0.0 4.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS63890.1 - 0.002 18.0 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Senescence PF06911.7 ETS63891.1 - 1.5e-46 158.3 5.9 1.5e-46 158.3 4.1 1.6 2 0 0 2 2 2 1 Senescence-associated protein Herpes_capsid PF06112.6 ETS63891.1 - 1.1 9.2 11.8 0.77 9.7 3.7 2.8 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein Epimerase PF01370.16 ETS63894.1 - 0.0001 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS63894.1 - 0.031 14.2 0.1 0.094 12.7 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding TPR_1 PF00515.23 ETS63895.1 - 1.4e-26 90.8 11.0 1.5e-05 24.3 0.0 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETS63895.1 - 2e-24 85.0 13.8 7.4e-11 41.5 0.4 5.8 4 1 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 ETS63895.1 - 1.9e-20 71.0 17.5 0.0008 19.1 0.1 9.2 10 0 0 10 10 10 5 Tetratricopeptide repeat APC8 PF04049.8 ETS63895.1 - 2e-19 69.7 0.0 8e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 ETS63895.1 - 4.6e-18 63.5 3.3 4.3e-05 23.0 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS63895.1 - 1.4e-15 57.0 18.8 2.5e-06 27.3 0.1 7.5 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETS63895.1 - 1.3e-12 47.1 13.8 0.0021 18.5 0.1 9.8 5 2 6 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS63895.1 - 5.9e-11 41.3 11.0 0.46 10.4 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 ETS63895.1 - 9.6e-11 41.6 10.5 0.0029 17.7 0.3 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETS63895.1 - 6.1e-10 39.5 2.8 1.7e-08 34.8 1.0 8.4 9 1 2 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS63895.1 - 4e-09 35.9 6.2 0.012 15.7 0.2 7.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS63895.1 - 7.5e-07 29.2 9.1 0.36 11.3 0.2 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS63895.1 - 2.2e-06 27.9 7.1 0.0052 17.0 0.0 5.7 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS63895.1 - 0.00013 21.7 20.2 0.11 12.3 0.1 6.9 5 1 1 7 7 7 3 Tetratricopeptide repeat Ribosomal_S6e PF01092.14 ETS63896.1 - 1.1e-57 193.2 0.2 1.1e-57 193.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e DUF2605 PF10792.4 ETS63896.1 - 0.4 10.3 3.2 0.63 9.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Ribosomal_S13_N PF08069.7 ETS63897.1 - 5.4e-26 90.2 0.1 5.4e-26 90.2 0.1 2.4 3 0 0 3 3 3 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 ETS63897.1 - 4.9e-22 77.4 0.1 8.3e-22 76.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 ETS63897.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 'Paired box' domain Arrestin_N PF00339.24 ETS63898.1 - 0.11 12.3 0.0 0.87 9.3 0.0 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 ETS63898.1 - 0.11 12.5 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain LRR_4 PF12799.2 ETS63899.1 - 3.2e-05 23.4 18.8 0.1 12.2 0.8 6.9 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 ETS63899.1 - 3.9e-05 23.2 8.0 9.1 6.6 0.1 8.0 9 0 0 9 9 9 1 Leucine Rich repeat LRR_8 PF13855.1 ETS63899.1 - 4.5e-05 23.1 6.3 2.3 8.0 0.2 4.7 4 0 0 4 4 4 3 Leucine rich repeat SeleniumBinding PF11524.3 ETS63899.1 - 0.23 11.6 0.0 5.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Selenium binding protein DUF500 PF04366.7 ETS63900.1 - 6.4e-39 132.2 0.0 1.4e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 ETS63900.1 - 6.6e-17 60.6 0.1 1.5e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS63900.1 - 9.3e-15 53.9 0.1 1.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS63900.1 - 5.5e-11 41.7 0.0 1.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Glyco_hydro_9 PF00759.14 ETS63901.1 - 4.6e-95 319.1 13.6 5.1e-93 312.3 9.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 VSP PF03302.8 ETS63901.1 - 0.0016 17.1 0.7 0.0033 16.1 0.2 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein Arf PF00025.16 ETS63902.1 - 8.3e-67 223.7 0.0 9.4e-67 223.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 ETS63902.1 - 4e-14 52.0 1.7 8.4e-10 37.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 ETS63902.1 - 4.2e-11 42.3 0.0 5.6e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETS63902.1 - 1.4e-09 37.4 0.0 1.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS63902.1 - 1.9e-09 38.0 0.0 2.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS63902.1 - 3.6e-08 33.3 0.0 8.8e-08 32.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 ETS63902.1 - 4.8e-08 32.5 0.0 5.4e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 ETS63902.1 - 6.2e-05 22.5 0.0 0.00096 18.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 ETS63902.1 - 0.0037 16.5 0.1 0.011 15.0 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 ETS63902.1 - 0.018 15.8 0.0 0.029 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETS63902.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PIG-U PF06728.8 ETS63903.1 - 3.3e-113 378.4 14.2 4.2e-113 378.0 9.8 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U MAT1 PF06391.8 ETS63904.1 - 6.6e-38 130.3 19.9 8.8e-38 129.8 13.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 ETS63904.1 - 0.00023 20.8 7.1 0.00073 19.2 5.1 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS63904.1 - 0.00026 20.5 9.6 0.0014 18.2 6.9 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS63904.1 - 0.00057 19.4 8.6 0.0023 17.5 6.1 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 ETS63904.1 - 0.0033 16.9 6.5 0.044 13.3 1.6 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 ETS63904.1 - 0.0061 16.5 10.2 0.13 12.3 7.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ISL3 PF14690.1 ETS63904.1 - 0.024 14.6 0.5 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-RING_2 PF13639.1 ETS63904.1 - 0.11 12.2 9.0 1.7 8.5 7.1 2.1 1 1 1 2 2 2 0 Ring finger domain DZR PF12773.2 ETS63904.1 - 0.24 11.2 6.5 0.77 9.6 4.5 1.8 1 1 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 ETS63904.1 - 0.96 9.1 6.4 0.52 10.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DDHD PF02862.12 ETS63904.1 - 1.2 8.9 6.5 2.1 8.1 4.5 1.4 1 0 0 1 1 1 0 DDHD domain zinc_ribbon_2 PF13240.1 ETS63904.1 - 2.8 7.5 8.3 1.4 8.4 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 ETS63904.1 - 3.6 7.6 10.4 13 5.7 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain DUF3798 PF12683.2 ETS63905.1 - 0.11 11.6 0.2 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) AMPKBI PF04739.10 ETS63907.1 - 4.6e-29 100.2 0.0 1.5e-28 98.5 0.0 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 ETS63907.1 - 0.065 13.2 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) RRM_1 PF00076.17 ETS63908.1 - 4.8e-06 26.1 0.0 9.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS63908.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS63908.1 - 0.00049 19.8 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 ETS63908.1 - 0.0025 17.4 2.1 0.0025 17.4 1.5 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETS63908.1 - 0.023 14.6 3.3 0.072 13.1 2.3 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type FYVE PF01363.16 ETS63908.1 - 0.45 10.4 5.3 4.1 7.3 3.7 2.5 1 1 0 1 1 1 0 FYVE zinc finger RNase_T PF00929.19 ETS63909.1 - 3.6e-11 43.6 0.0 7.4e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Exonuclease SAP PF02037.22 ETS63909.1 - 1.7e-09 36.9 4.1 2e-09 36.7 2.0 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 ETS63909.1 - 0.0048 16.4 0.2 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain Complex1_LYR PF05347.10 ETS63911.1 - 1.7e-07 30.9 0.0 5.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS63911.1 - 6.2e-06 26.3 0.2 1.6e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L31 PF01197.13 ETS63911.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 DNA_pol_viral_N PF00242.12 ETS63911.1 - 0.51 9.3 4.2 0.68 8.9 2.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SlyX PF04102.7 ETS63912.1 - 0.023 15.0 4.3 0.045 14.1 0.0 3.0 3 2 1 4 4 4 0 SlyX Nsp1_C PF05064.8 ETS63912.1 - 0.094 12.3 1.3 0.69 9.5 0.1 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region FliJ PF02050.11 ETS63912.1 - 0.36 10.8 4.4 2.1 8.3 0.1 2.7 3 0 0 3 3 3 0 Flagellar FliJ protein HECT PF00632.20 ETS63913.1 - 5.1e-92 308.4 0.1 7.5e-92 307.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 ETS63913.1 - 4.7e-32 109.4 21.0 4.1e-11 42.5 2.1 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 ETS63913.1 - 5.2e-16 58.2 0.2 1.4e-15 56.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain Nuc_sug_transp PF04142.10 ETS63914.1 - 6.5e-09 35.2 0.1 1.1e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 ETS63914.1 - 9.3e-08 31.3 7.7 9.3e-08 31.3 5.4 1.4 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 ETS63914.1 - 2e-05 24.2 17.4 0.0045 16.6 6.1 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 ETS63914.1 - 0.00052 20.0 4.5 0.00052 20.0 3.2 3.7 3 1 1 4 4 4 1 EamA-like transporter family Hist_deacetyl PF00850.14 ETS63915.1 - 1.2e-79 267.7 0.0 1.6e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Adaptin_N PF01602.15 ETS63916.1 - 2.4e-148 494.7 5.9 2.8e-148 494.5 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 ETS63916.1 - 1.3e-22 80.2 0.5 2.3e-22 79.4 0.4 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 ETS63916.1 - 1.5e-09 37.9 1.5 0.1 12.9 0.0 6.0 4 3 1 5 5 5 4 HEAT repeats HEAT PF02985.17 ETS63916.1 - 0.0013 18.6 0.2 23 5.3 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 ETS63916.1 - 0.0085 15.6 4.8 0.062 12.8 0.2 3.9 3 2 1 4 4 4 1 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 ETS63916.1 - 0.068 13.0 8.7 0.071 12.9 0.6 3.8 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 RINGv PF12906.2 ETS63917.1 - 2e-10 40.5 3.6 3.5e-10 39.7 2.5 1.4 1 0 0 1 1 1 1 RING-variant domain Cytochrom_C552 PF02335.10 ETS63917.1 - 0.039 12.6 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c552 Uricase PF01014.13 ETS63920.1 - 2e-63 212.5 0.0 2.2e-35 121.7 0.1 2.1 2 0 0 2 2 2 2 Uricase GLTP PF08718.6 ETS63921.1 - 1.3e-43 148.5 0.0 1.9e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF1798 PF08807.5 ETS63921.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) WD40 PF00400.27 ETS63922.1 - 3.3e-11 42.6 5.1 0.0029 17.4 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ABC1 PF03109.11 ETS63923.1 - 1.1e-21 76.9 0.0 7.1e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 ABC1 family AdoMet_MTase PF07757.8 ETS63924.1 - 4.9e-35 120.0 0.0 8.3e-35 119.2 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 ETS63924.1 - 9.9e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS63924.1 - 0.0024 18.4 0.0 0.0044 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS63924.1 - 0.0028 17.3 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS63924.1 - 0.0087 15.6 0.1 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS63924.1 - 0.04 13.9 0.1 0.091 12.7 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS63924.1 - 0.042 14.3 0.0 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 ETS63924.1 - 0.085 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MFS_1 PF07690.11 ETS63925.1 - 2e-42 145.1 58.4 1.5e-38 132.4 26.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS63925.1 - 3.7e-13 48.8 8.3 3.7e-13 48.8 5.7 2.9 1 1 0 2 2 2 1 Sugar (and other) transporter APC10 PF03256.11 ETS63926.1 - 8.1e-46 156.0 0.0 1.2e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 ETS63926.1 - 0.11 10.9 0.7 0.14 10.6 0.5 1.2 1 0 0 1 1 1 0 Daxx Family zf-Tim10_DDP PF02953.10 ETS63927.1 - 3e-22 77.6 0.9 3.8e-22 77.3 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.6 ETS63927.1 - 0.12 12.1 0.6 0.15 11.8 0.3 1.3 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein Acyltransferase PF01553.16 ETS63928.1 - 2.1e-21 75.7 0.0 3.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Transpep_BrtH PF14399.1 ETS63928.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase NAD_binding_1 PF00175.16 ETS63929.1 - 6.1e-07 29.9 0.0 0.012 16.2 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS63929.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETS63929.1 - 0.016 15.0 0.1 0.22 11.3 0.0 2.2 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Exo_endo_phos PF03372.18 ETS63930.1 - 1.7e-11 44.5 1.4 2.3e-11 44.1 1.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DKCLD PF08068.7 ETS63931.1 - 1.5e-29 101.7 0.3 1.4e-28 98.5 0.0 2.7 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 ETS63931.1 - 1.3e-24 87.0 0.3 1.3e-21 77.3 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 ETS63931.1 - 2.9e-20 71.7 1.3 6e-20 70.7 0.9 1.6 1 0 0 1 1 1 1 PUA domain Ribosomal_L22e PF01776.12 ETS63932.1 - 1.6e-47 160.0 0.4 1.9e-47 159.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family SSB PF00436.20 ETS63932.1 - 0.1 12.4 0.2 0.19 11.6 0.1 1.5 2 0 0 2 2 2 0 Single-strand binding protein family WD40 PF00400.27 ETS63933.1 - 7.2e-25 85.9 14.9 1.3e-07 31.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Minor_capsid_2 PF11114.3 ETS63933.1 - 0.067 13.0 0.3 0.42 10.4 0.2 2.2 2 0 0 2 2 2 0 Minor capsid protein BBS2_Mid PF14783.1 ETS63933.1 - 0.08 12.7 0.0 18 5.1 0.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 ETS63933.1 - 0.094 10.8 0.0 0.33 9.0 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETS63933.1 - 0.13 10.9 0.1 8.7 4.9 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Peptidase_M28 PF04389.12 ETS63934.1 - 1.4e-26 93.3 0.2 2.5e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 ETS63934.1 - 1.5e-06 27.8 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LTV PF04180.9 ETS63935.1 - 1.3e-47 163.2 11.1 1.3e-47 163.2 7.7 3.5 2 2 1 3 3 3 1 Low temperature viability protein EXOSC1 PF10447.4 ETS63936.1 - 1.8e-29 101.5 0.0 2.7e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 ETS63936.1 - 0.004 16.4 1.9 0.04 13.2 1.3 2.6 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pkinase PF00069.20 ETS63937.1 - 3.3e-53 180.4 0.0 8.6e-53 179.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63937.1 - 9.2e-25 87.1 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS63937.1 - 0.025 14.3 0.3 0.075 12.7 0.2 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_62 PF03664.8 ETS63938.1 - 7.5e-141 467.9 5.9 8.7e-141 467.7 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 GPI-anchored PF10342.4 ETS63939.1 - 1e-09 38.7 1.0 1e-09 38.7 0.7 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pescadillo_N PF06732.6 ETS63940.1 - 1.9e-116 388.2 0.1 1.9e-116 388.2 0.1 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 ETS63940.1 - 0.0047 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Acyl-CoA_dh_1 PF00441.19 ETS63941.1 - 3.2e-34 118.2 5.8 7.1e-34 117.0 4.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS63941.1 - 3.6e-19 68.0 0.1 1.1e-18 66.4 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS63941.1 - 5.1e-17 62.4 1.8 1.3e-16 61.1 0.1 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS63941.1 - 3.6e-12 46.6 6.4 3.6e-12 46.6 4.4 3.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_20 PF00728.17 ETS63942.1 - 1.6e-77 261.0 0.0 2.6e-77 260.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 ETS63942.1 - 1.4e-14 54.8 0.0 3.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 ETS63942.1 - 1.3e-06 28.9 0.0 8.5e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 UCH PF00443.24 ETS63943.1 - 4.5e-29 101.3 0.0 6.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 ETS63943.1 - 4.8e-11 42.6 0.2 9.8e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 ETS63943.1 - 1.1e-06 28.3 0.0 1.3e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ODC_AZ PF02100.12 ETS63944.1 - 3.9e-25 87.4 0.0 6.5e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Es2 PF09751.4 ETS63945.1 - 6.6e-76 256.3 0.5 8.1e-76 256.0 0.4 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 ADH_zinc_N PF00107.21 ETS63946.1 - 1e-13 50.9 0.0 3.9e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS63946.1 - 2.5e-11 43.3 0.0 5.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.27 ETS63948.1 - 1.1e-52 174.1 19.6 1.1e-08 34.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat 4HBT_2 PF13279.1 ETS63949.1 - 4.3e-13 49.7 0.1 5.6e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 ETS63949.1 - 0.00014 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 ETS63949.1 - 0.00094 18.1 0.0 0.0022 16.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-ACP thioesterase PPR_2 PF13041.1 ETS63950.1 - 1.1e-08 34.8 0.0 0.38 10.7 0.0 7.4 10 0 0 10 10 10 3 PPR repeat family PPR_3 PF13812.1 ETS63950.1 - 3e-06 27.0 8.1 2.5 8.6 0.0 7.8 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 ETS63950.1 - 6e-05 22.7 2.7 3.6 7.7 0.0 6.0 8 0 0 8 8 8 2 PPR repeat DEP PF00610.16 ETS63950.1 - 0.098 12.4 0.0 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GATA PF00320.22 ETS63951.1 - 3.7e-14 51.7 5.4 6.7e-14 50.9 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger Ycf1 PF05758.7 ETS63951.1 - 1.2 6.7 7.9 1.8 6.1 5.5 1.2 1 0 0 1 1 1 0 Ycf1 Hepar_II_III PF07940.8 ETS63952.1 - 8.8e-10 38.5 1.8 1.7e-09 37.6 0.4 2.2 2 0 0 2 2 2 1 Heparinase II/III-like protein Arc_PepC_II PF06847.6 ETS63952.1 - 0.018 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Pyr_redox_3 PF13738.1 ETS63953.1 - 2.3e-25 89.8 0.0 1.3e-23 84.1 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS63953.1 - 4.6e-11 42.2 0.0 1.1e-07 31.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS63953.1 - 5e-11 42.4 0.0 1.7e-10 40.7 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS63953.1 - 1.2e-10 40.8 0.0 4.9e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.14 ETS63953.1 - 4.6e-10 38.3 1.0 5.8e-09 34.6 0.7 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 ETS63953.1 - 1.7e-06 27.8 0.0 0.0062 16.3 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS63953.1 - 1.8e-05 23.8 0.0 0.055 12.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS63953.1 - 3.2e-05 23.9 0.0 0.24 11.2 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS63953.1 - 0.00096 18.3 0.0 0.015 14.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 ETS63953.1 - 0.009 14.6 0.0 0.082 11.5 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 ETS63953.1 - 0.011 16.1 0.0 0.14 12.5 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS63953.1 - 0.021 13.7 0.0 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 ETS63953.1 - 0.04 14.0 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 ETS63953.1 - 0.09 11.8 0.0 5.2 6.0 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.10 ETS63953.1 - 0.17 10.0 0.0 0.63 8.1 0.0 1.9 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Tim17 PF02466.14 ETS63954.1 - 8.1e-34 116.4 3.9 9.5e-34 116.2 2.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sec5 PF15469.1 ETS63955.1 - 1.6e-54 184.4 0.0 3.1e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 ETS63955.1 - 0.093 12.5 0.0 0.32 10.8 0.0 2.0 1 0 0 1 1 1 0 Vps51/Vps67 PA28_beta PF02252.13 ETS63956.1 - 3.7e-49 166.0 0.1 5.6e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 ETS63956.1 - 0.0025 17.9 0.0 0.007 16.5 0.0 1.8 1 1 0 1 1 1 1 Proteasome activator pa28 alpha subunit Sipho_Gp157 PF05565.6 ETS63956.1 - 0.0096 15.5 0.4 0.029 13.9 0.1 1.8 2 0 0 2 2 2 1 Siphovirus Gp157 ABC_membrane PF00664.18 ETS63957.1 - 3.4e-63 213.6 28.5 2.2e-35 122.4 5.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS63957.1 - 9.7e-55 184.6 0.1 3.3e-30 105.1 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 ETS63957.1 - 3.3e-12 46.9 0.1 0.058 13.3 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 ETS63957.1 - 3.9e-10 39.3 0.3 0.00063 19.0 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS63957.1 - 5.9e-07 28.9 0.7 0.044 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 ETS63957.1 - 4.4e-06 27.1 0.6 0.12 12.8 0.2 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 ETS63957.1 - 5.4e-06 26.3 0.5 0.016 15.1 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 ETS63957.1 - 2.3e-05 23.8 0.8 0.031 13.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETS63957.1 - 4.1e-05 24.0 3.6 0.22 11.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 ETS63957.1 - 0.00014 22.6 0.0 1.2 10.0 0.0 3.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS63957.1 - 0.00019 20.6 1.9 0.24 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS63957.1 - 0.00037 20.5 8.1 0.061 13.3 0.1 3.6 4 1 1 5 5 3 2 AAA ATPase domain Zeta_toxin PF06414.7 ETS63957.1 - 0.00049 19.2 0.4 0.31 10.1 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin ArgK PF03308.11 ETS63957.1 - 0.0006 18.6 0.7 0.24 10.1 0.1 2.4 2 0 0 2 2 2 2 ArgK protein FtsK_SpoIIIE PF01580.13 ETS63957.1 - 0.0013 18.2 0.2 0.5 9.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 ETS63957.1 - 0.0021 17.8 3.9 0.63 9.8 0.1 2.9 2 0 0 2 2 2 2 Dynamin family MobB PF03205.9 ETS63957.1 - 0.0035 17.0 0.6 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 ETS63957.1 - 0.0052 15.7 1.4 1.8 7.3 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETS63957.1 - 0.0069 16.5 0.5 4.5 7.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 ETS63957.1 - 0.0078 15.6 0.2 1.3 8.4 0.1 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 ETS63957.1 - 0.0084 15.9 1.5 1.9 8.3 0.1 3.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 ETS63957.1 - 0.01 15.5 0.1 0.73 9.4 0.0 2.9 2 1 0 2 2 2 0 Archaeal ATPase ATP_bind_1 PF03029.12 ETS63957.1 - 0.015 14.8 1.1 1 8.8 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 ETS63957.1 - 0.018 14.6 2.4 3.9 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 ETS63957.1 - 0.019 14.6 0.3 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 ETS63957.1 - 0.057 12.8 1.7 7 6.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 ETS63957.1 - 0.057 12.3 0.2 4.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 ETS63957.1 - 0.11 12.2 2.4 0.57 9.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 ETS63957.1 - 0.4 10.9 2.5 13 6.0 0.1 3.0 2 0 0 2 2 2 0 AAA domain NPL4 PF05021.10 ETS63958.1 - 4.7e-101 337.9 0.0 7.4e-101 337.3 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 ETS63958.1 - 7.5e-67 223.5 1.0 1.2e-66 222.8 0.7 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 ETS63958.1 - 0.0012 19.0 0.0 0.0035 17.5 0.0 1.7 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Metallophos_C PF14008.1 ETS63958.1 - 0.041 13.9 0.2 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Iron/zinc purple acid phosphatase-like protein C RRM_6 PF14259.1 ETS63959.1 - 1.8e-11 43.8 0.0 7.9e-10 38.5 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS63959.1 - 5.5e-11 41.9 0.0 1.1e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS63959.1 - 0.00021 21.0 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.10 ETS63960.1 - 1.1e-21 75.8 0.5 1.5e-21 75.4 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger STAT6_C PF14596.1 ETS63960.1 - 0.058 13.3 0.0 0.08 12.8 0.0 1.4 1 1 0 1 1 1 0 STAT6 C-terminal Sugar_tr PF00083.19 ETS63962.1 - 4e-104 348.7 11.8 4.7e-104 348.4 8.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS63962.1 - 1.9e-22 79.5 23.2 1.9e-22 79.5 16.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily SDA1 PF05285.7 ETS63962.1 - 0.58 9.3 3.6 0.92 8.7 2.5 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETS63962.1 - 2.8 5.8 5.0 4.2 5.2 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 ETS63963.1 - 5.5e-69 232.1 0.0 9.4e-69 231.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS63963.1 - 2.6e-48 164.3 0.0 4.1e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS63963.1 - 0.00037 19.5 0.0 0.00072 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Aldo_ket_red PF00248.16 ETS63964.1 - 2.8e-57 193.6 0.0 3.2e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAXNEB PF05625.6 ETS63965.1 - 2e-38 132.1 0.0 1.9e-25 89.4 0.0 3.3 3 1 0 3 3 3 3 PAXNEB protein Ferritin_2 PF13668.1 ETS63966.1 - 1.4e-43 148.1 2.0 2.3e-43 147.4 1.4 1.4 1 0 0 1 1 1 1 Ferritin-like domain PAP2 PF01569.16 ETS63967.1 - 7.1e-15 54.8 3.3 1.1e-14 54.2 2.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 ETS63967.1 - 8.6e-05 22.2 1.4 0.00082 19.1 0.1 2.4 2 0 0 2 2 2 1 Divergent PAP2 family DUF2614 PF11023.3 ETS63967.1 - 0.16 11.7 2.1 0.18 11.5 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) DUF4203 PF13886.1 ETS63967.1 - 0.29 10.5 6.1 0.029 13.8 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) Rep_fac_C PF08542.6 ETS63968.1 - 9.5e-20 70.3 0.1 2.7e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 ETS63968.1 - 1.9e-12 47.1 0.0 1.3e-10 41.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 ETS63968.1 - 3e-12 46.8 0.0 7.1e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETS63968.1 - 2.1e-06 27.6 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 ETS63968.1 - 2.9e-06 26.2 0.0 0.0039 15.9 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 ETS63968.1 - 5.1e-06 26.6 0.1 0.00031 20.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 ETS63968.1 - 1.7e-05 24.3 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS63968.1 - 0.00014 21.9 0.1 0.0095 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS63968.1 - 0.0004 19.5 0.0 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 ETS63968.1 - 0.00074 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 ETS63968.1 - 0.001 18.8 0.1 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 ETS63968.1 - 0.0021 17.5 0.1 0.32 10.3 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_5 PF07728.9 ETS63968.1 - 0.006 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS63968.1 - 0.014 14.5 0.0 0.2 10.8 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 ETS63968.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 ETS63968.1 - 0.045 13.2 0.1 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 ETS63968.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MipZ PF09140.6 ETS63968.1 - 0.049 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ NTPase_1 PF03266.10 ETS63968.1 - 0.055 13.1 0.2 0.56 9.8 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_31 PF13614.1 ETS63968.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS63968.1 - 0.15 11.4 0.2 0.43 9.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF1302 PF06980.6 ETS63968.1 - 0.16 10.5 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) SNF2_N PF00176.18 ETS63969.1 - 1.1e-54 185.3 0.0 1.5e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS63969.1 - 9.4e-16 57.4 0.0 2.8e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 ETS63969.1 - 4.8e-08 32.5 2.6 0.011 15.3 0.1 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.3 ETS63969.1 - 1.5e-07 30.5 0.0 3.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 ETS63969.1 - 1.1e-06 28.6 0.0 5e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-PHD-like PF15446.1 ETS63969.1 - 0.0006 19.1 5.2 0.43 9.8 0.1 3.3 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD PF00628.24 ETS63969.1 - 0.0059 16.2 10.2 0.013 15.1 0.8 3.0 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 ETS63969.1 - 0.58 9.9 9.6 1.3 8.8 0.0 3.7 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ORC4_C PF14629.1 ETS63970.1 - 6e-41 140.0 0.1 2.9e-40 137.8 0.0 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 ETS63970.1 - 8.5e-29 100.8 1.8 8.5e-29 100.8 1.3 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS63970.1 - 3.7e-06 27.0 0.0 7e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETS63970.1 - 3.9e-06 27.0 0.0 0.071 13.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETS63970.1 - 0.00016 20.6 0.0 0.00031 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 ETS63970.1 - 0.00024 20.5 0.0 0.00068 19.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 ETS63970.1 - 0.0025 17.4 0.0 0.0064 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.2 ETS63970.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 ABC_tran PF00005.22 ETS63970.1 - 0.056 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 ETS63970.1 - 0.06 13.0 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 ETS63970.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Pox_A32 PF04665.7 ETS63970.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Utp11 PF03998.8 ETS63972.1 - 1.4e-67 228.0 5.7 2.3e-67 227.3 4.0 1.3 1 0 0 1 1 1 1 Utp11 protein CtaG_Cox11 PF04442.9 ETS63972.1 - 2.9e-53 179.7 0.0 4.5e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 MFS_1 PF07690.11 ETS63973.1 - 2.6e-26 92.1 22.1 3.3e-25 88.5 16.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ORMDL PF04061.9 ETS63973.1 - 0.067 12.7 4.0 0.084 12.4 1.0 2.2 2 0 0 2 2 2 0 ORMDL family DUF4407 PF14362.1 ETS63974.1 - 0.0013 17.7 0.9 0.0019 17.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF1240 PF06836.7 ETS63974.1 - 0.031 14.5 1.4 0.17 12.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) NfeD PF01957.13 ETS63974.1 - 0.32 11.1 2.6 0.15 12.1 0.3 1.6 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Tetraspannin PF00335.15 ETS63974.1 - 0.33 10.2 13.7 0.034 13.4 5.3 1.9 1 1 0 2 2 2 0 Tetraspanin family zf-DHHC PF01529.15 ETS63974.1 - 1.8 7.8 8.9 0.15 11.4 2.4 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase CPSF_A PF03178.10 ETS63975.1 - 1.6e-90 303.5 0.1 2.7e-89 299.4 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 ETS63975.1 - 3.8e-73 246.3 0.0 6.9e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RhoGEF PF00621.15 ETS63977.1 - 4.6e-42 143.9 0.0 7.5e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 ETS63977.1 - 4.4e-13 48.5 2.6 3e-05 23.5 0.2 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS63977.1 - 2.9e-11 42.9 7.9 7.2e-07 28.8 0.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 ETS63977.1 - 3.7e-07 29.2 7.5 0.12 12.4 0.2 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 ETS63977.1 - 0.00021 20.9 8.0 1.5 9.3 1.3 5.2 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 ETS63977.1 - 7.7 6.9 5.6 41 4.6 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat TLD PF07534.11 ETS63978.1 - 3.9e-28 98.1 0.0 1.4e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 TLD SMC_N PF02463.14 ETS63981.1 - 3.1e-27 95.2 0.0 8e-27 93.9 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS63981.1 - 2.4e-13 50.9 26.7 2.4e-13 50.9 18.5 5.8 3 2 0 3 3 2 1 AAA domain AAA_21 PF13304.1 ETS63981.1 - 2.1e-08 34.4 0.6 0.00022 21.2 0.1 3.3 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 ETS63981.1 - 1.3e-05 24.6 0.1 2.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 ETS63981.1 - 1.5e-05 24.2 0.2 1.5e-05 24.2 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain IFT57 PF10498.4 ETS63981.1 - 0.001 17.8 7.8 0.001 17.8 5.4 5.5 3 2 2 6 6 5 1 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.3 ETS63981.1 - 0.0012 18.6 2.6 0.0012 18.6 1.8 8.1 5 3 2 10 10 7 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 ETS63981.1 - 0.0056 16.4 8.1 0.0056 16.4 5.6 8.0 4 2 3 7 7 6 1 TPR/MLP1/MLP2-like protein ABC_tran PF00005.22 ETS63981.1 - 0.0063 16.8 0.1 0.0063 16.8 0.1 5.7 3 2 1 4 4 2 1 ABC transporter DUF4200 PF13863.1 ETS63981.1 - 0.0096 15.8 21.0 0.0096 15.8 14.6 7.5 3 2 3 7 7 5 2 Domain of unknown function (DUF4200) AAA_13 PF13166.1 ETS63981.1 - 0.026 12.9 0.1 0.026 12.9 0.1 4.9 4 2 1 5 5 5 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS63981.1 - 0.049 13.0 0.0 0.049 13.0 0.0 4.4 5 0 0 5 5 5 0 FtsK/SpoIIIE family AAA_18 PF13238.1 ETS63981.1 - 0.27 11.5 0.0 0.27 11.5 0.0 4.4 4 2 0 4 4 3 0 AAA domain AAA_25 PF13481.1 ETS63981.1 - 1.3 8.3 6.1 0.84 8.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF106 PF01956.11 ETS63981.1 - 1.6 8.2 0.0 1.6 8.2 0.0 4.5 2 2 1 3 3 2 0 Integral membrane protein DUF106 Reo_sigmaC PF04582.7 ETS63981.1 - 1.7 7.7 13.4 1.4 8.0 0.2 4.0 2 1 1 4 4 4 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETS63981.1 - 7.3 6.4 38.8 0.34 10.7 0.1 6.0 2 2 3 6 6 6 0 Protein of unknown function (DUF1664) ApbA_C PF08546.6 ETS63982.1 - 2.8e-37 127.5 0.0 4.9e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 ETS63982.1 - 7.1e-23 80.7 0.0 1.3e-18 66.8 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA DUF3591 PF12157.3 ETS63983.1 - 1.2e-191 637.0 1.9 1.8e-191 636.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 ETS63983.1 - 0.0002 20.9 3.0 0.00048 19.7 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle NTR2 PF15458.1 ETS63984.1 - 2.1e-33 115.6 0.3 2.1e-33 115.6 0.2 1.7 2 0 0 2 2 2 1 Nineteen complex-related protein 2 PBP1_TM PF14812.1 ETS63984.1 - 0.26 11.5 7.1 0.36 11.1 2.2 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1253 PF06862.7 ETS63985.1 - 7.2e-158 525.6 0.2 8.8e-158 525.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MSA-2c PF12238.3 ETS63985.1 - 0.16 11.6 5.2 0.37 10.4 3.6 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c MSP1_C PF07462.6 ETS63985.1 - 1.1 7.5 5.1 1.7 6.9 3.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TFIIA PF03153.8 ETS63985.1 - 9.4 6.0 9.9 0.64 9.8 3.0 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MMR_HSR1 PF01926.18 ETS63986.1 - 5.4e-16 58.5 0.1 8.9e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS63986.1 - 4.2e-05 22.8 0.0 0.00025 20.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 ETS63986.1 - 6.1e-05 22.2 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 ETS63986.1 - 0.0083 15.9 1.2 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 ETS63986.1 - 0.0096 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 ETS63986.1 - 0.03 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 ETS63986.1 - 0.069 12.5 0.0 0.72 9.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nop14 PF04147.7 ETS63986.1 - 0.16 9.8 10.9 0.27 9.1 7.5 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 ETS63986.1 - 2.2 7.8 9.7 4.2 6.8 6.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Img2 PF05046.9 ETS63987.1 - 4.4e-28 97.3 0.0 8.1e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 ETS63987.1 - 0.13 12.0 0.0 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 SecE PF00584.15 ETS63988.1 - 2.9e-08 33.1 0.4 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 2 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_L29 PF00831.18 ETS63989.1 - 1.1e-18 66.6 2.5 1.1e-18 66.6 1.7 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 ETS63989.1 - 0.0073 16.5 1.7 0.0089 16.2 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF1013 PF06242.6 ETS63989.1 - 0.12 12.3 0.9 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) HiaBD2 PF15403.1 ETS63989.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF896 PF05979.7 ETS63989.1 - 0.18 11.4 0.3 0.18 11.4 0.2 2.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) DUF3460 PF11943.3 ETS63991.1 - 0.048 13.7 0.4 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) SF3b10 PF07189.6 ETS63993.1 - 1.1e-29 102.0 0.0 1.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Zn_clus PF00172.13 ETS63995.1 - 0.00029 20.6 15.1 0.00044 20.0 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 ETS63996.1 - 5.2e-70 235.6 0.8 5.2e-70 235.6 0.5 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 ETS63996.1 - 1.2e-52 177.7 18.8 1.2e-52 177.7 13.0 2.6 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 ETS63996.1 - 7.7e-13 48.1 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS63996.1 - 1.1e-05 25.3 0.0 3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 ETS63996.1 - 1.2e-05 24.3 0.0 0.00012 20.9 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Swi5 PF07061.6 ETS63999.1 - 2.9e-15 55.8 0.1 3.9e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Swi5 Integrase_Zn PF02022.14 ETS63999.1 - 0.086 12.3 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain Pex14_N PF04695.8 ETS64000.1 - 6.7e-17 61.8 0.5 2e-16 60.2 0.0 2.1 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Fun_ATP-synt_8 PF05933.8 ETS64000.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) GDI PF00996.13 ETS64001.1 - 1.2e-200 666.4 0.0 1.3e-200 666.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 ETS64001.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2404 PF10296.4 ETS64002.1 - 1.9e-29 101.6 0.0 3.3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) SET PF00856.23 ETS64003.1 - 1.9e-07 31.5 0.0 5.6e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 SET domain dCMP_cyt_deam_1 PF00383.17 ETS64003.1 - 0.00011 21.7 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region HLH PF00010.21 ETS64004.1 - 0.00086 18.9 0.0 0.0028 17.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain GHMP_kinases_N PF00288.21 ETS64005.1 - 4.8e-13 48.9 1.7 1.3e-12 47.6 1.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS64005.1 - 1.5e-05 25.0 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Telomerase_RBD PF12009.3 ETS64006.1 - 2.6e-36 124.5 0.1 1.6e-35 121.9 0.0 2.3 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 ETS64006.1 - 2.1e-13 50.1 0.0 3e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 ETS64007.1 - 6.7e-49 166.3 0.0 1.2e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64007.1 - 1.4e-23 83.2 0.0 1.7e-21 76.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS64007.1 - 0.019 13.9 0.0 0.058 12.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like MACPF PF01823.14 ETS64009.1 - 0.15 11.7 3.5 0.29 10.8 2.4 1.4 1 0 0 1 1 1 0 MAC/Perforin domain Ank_4 PF13637.1 ETS64010.1 - 3.6e-12 46.4 0.0 8.8e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS64010.1 - 4.8e-08 33.2 0.2 9.2e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS64010.1 - 5.6e-08 32.7 0.4 0.00025 21.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS64010.1 - 3.1e-07 29.8 0.2 1.1e-05 24.9 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 ETS64010.1 - 0.00011 22.0 0.0 0.0062 16.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_2 PF14608.1 ETS64010.1 - 0.0036 17.2 2.4 0.0066 16.4 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type PPR_2 PF13041.1 ETS64011.1 - 1.1e-05 25.2 0.1 1.5 8.8 0.0 4.4 4 0 0 4 4 4 2 PPR repeat family WEMBL PF05701.6 ETS64011.1 - 0.00017 20.2 53.3 0.00017 20.2 36.9 11.9 2 1 8 10 10 10 6 Weak chloroplast movement under blue light IncA PF04156.9 ETS64011.1 - 0.0027 17.3 25.0 0.0027 17.3 17.3 22.1 4 2 17 23 23 23 10 IncA protein DUF4201 PF13870.1 ETS64011.1 - 0.003 17.0 10.8 0.003 17.0 7.5 23.3 4 2 14 23 23 23 5 Domain of unknown function (DUF4201) Adaptin_N PF01602.15 ETS64012.1 - 4.1e-110 368.5 0.0 6.1e-110 368.0 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 ETS64012.1 - 8.1e-55 184.7 0.6 1.6e-54 183.8 0.4 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 ETS64012.1 - 1.1e-13 51.2 2.5 0.00052 20.2 0.0 6.6 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.17 ETS64012.1 - 4.1e-05 23.3 5.3 3 8.1 0.1 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_PBS PF03130.11 ETS64012.1 - 0.37 11.3 3.3 12 6.7 0.1 4.7 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat zf-Nse PF11789.3 ETS64013.1 - 5.7e-13 48.1 0.0 9.8e-13 47.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 ETS64013.1 - 8.7e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 ETS64013.1 - 0.011 15.4 0.2 0.04 13.6 0.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.20 ETS64013.1 - 0.025 14.2 0.1 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRF PF01765.14 ETS64013.1 - 0.074 12.5 1.3 0.15 11.5 0.9 1.6 1 1 0 1 1 1 0 Ribosome recycling factor zf-C3HC4_2 PF13923.1 ETS64013.1 - 0.14 12.2 0.2 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CTP_synth_N PF06418.9 ETS64014.1 - 1.8e-116 388.0 0.0 2.6e-116 387.5 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 ETS64014.1 - 2.1e-49 167.6 0.0 7.5e-39 133.1 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.18 ETS64014.1 - 0.0022 17.4 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 ETS64014.1 - 0.088 12.2 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Ribosomal_S28e PF01200.13 ETS64016.1 - 7.5e-28 96.0 3.7 1.2e-27 95.4 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S28e Chorion_2 PF03964.10 ETS64016.1 - 0.4 11.2 4.4 0.64 10.6 3.1 1.3 1 0 0 1 1 1 0 Chorion family 2 DUF336 PF03928.9 ETS64017.1 - 7.1e-16 58.2 0.0 9.3e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Ras PF00071.17 ETS64018.1 - 1.4e-54 183.8 0.0 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS64018.1 - 1.2e-17 64.5 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS64018.1 - 5.2e-06 25.8 0.0 6.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family UQ_con PF00179.21 ETS64019.1 - 7.7e-23 80.4 0.0 1.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rav1p_C PF12234.3 ETS64020.1 - 4.5e-192 639.5 0.0 6.1e-192 639.1 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal PP-binding PF00550.20 ETS64021.1 - 6.6e-14 51.9 0.8 9.7e-14 51.3 0.6 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 ETS64021.1 - 2.5e-08 33.8 0.5 3.6e-08 33.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 ETS64021.1 - 0.07 13.1 0.1 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S Ribosomal_L17 PF01196.14 ETS64022.1 - 1.7e-30 105.4 0.1 7.6e-30 103.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 PPR_2 PF13041.1 ETS64023.1 - 2.8e-08 33.5 0.0 0.7 9.9 0.0 5.9 5 1 2 7 7 7 3 PPR repeat family PPR_3 PF13812.1 ETS64023.1 - 3.6e-08 33.0 7.2 1.1 9.7 0.0 7.4 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 ETS64023.1 - 0.0045 16.8 0.0 2.8 8.1 0.0 5.0 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 ETS64023.1 - 0.0064 15.9 0.0 4.4 6.8 0.0 3.6 4 0 0 4 4 4 1 PPR repeat B12-binding_2 PF02607.12 ETS64023.1 - 0.025 14.6 0.5 6 6.9 0.0 3.9 4 0 0 4 4 4 0 B12 binding domain VPEP PF07589.6 ETS64024.1 - 0.8 9.6 5.3 0.12 12.3 0.8 1.9 2 0 0 2 2 2 0 PEP-CTERM motif PH PF00169.24 ETS64025.1 - 1.9e-05 24.7 0.0 0.00063 19.9 0.0 2.7 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 ETS64025.1 - 0.16 12.1 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Bin3 PF06859.7 ETS64026.1 - 3.8e-25 87.9 0.0 7.1e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Heme_oxygenase PF01126.15 ETS64026.1 - 1.6e-23 83.3 0.0 1.1e-19 70.8 0.0 2.8 2 1 0 2 2 2 2 Heme oxygenase Methyltransf_18 PF12847.2 ETS64026.1 - 7.6e-11 42.5 0.0 7.4e-09 36.1 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS64026.1 - 1.6e-09 38.0 0.0 5.5e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 ETS64026.1 - 2.4e-08 33.8 0.0 7.1e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS64026.1 - 3.3e-08 33.2 0.0 1.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS64026.1 - 7.1e-07 29.6 0.0 0.056 13.9 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 ETS64026.1 - 0.00014 22.1 0.0 0.44 10.9 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.1 ETS64026.1 - 0.0014 18.2 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS64026.1 - 0.0032 17.4 3.1 0.0039 17.2 0.5 2.3 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 ETS64026.1 - 0.0057 15.9 0.0 0.036 13.3 0.0 2.0 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain DUF2414 PF10309.4 ETS64027.1 - 2.1e-05 24.1 0.0 8e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 ETS64027.1 - 0.00076 19.4 0.0 0.002 18.0 0.0 1.6 2 0 0 2 2 2 1 RNA binding domain RRM_6 PF14259.1 ETS64027.1 - 0.045 13.7 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS64027.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Rsm22 PF09243.5 ETS64028.1 - 6.9e-28 97.4 0.1 1.7e-13 50.2 0.0 4.7 4 1 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Ima1_N PF09779.4 ETS64029.1 - 4e-18 66.1 4.3 4e-18 66.1 3.0 2.6 2 1 0 2 2 2 1 Ima1 N-terminal domain Chorion_2 PF03964.10 ETS64029.1 - 0.039 14.5 1.4 0.51 10.9 0.0 2.7 2 0 0 2 2 2 0 Chorion family 2 Lyase_1 PF00206.15 ETS64030.1 - 1.9e-117 391.9 0.0 2.8e-117 391.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 ETS64030.1 - 4.1e-20 71.6 1.0 1.5e-18 66.5 0.1 2.5 2 0 0 2 2 2 1 Fumarase C C-terminus MMR_HSR1 PF01926.18 ETS64031.1 - 5.8e-11 42.3 0.0 3.3e-10 39.9 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS64031.1 - 0.026 14.5 1.6 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain FeoB_N PF02421.13 ETS64031.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 ETS64031.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Carn_acyltransf PF00755.15 ETS64032.1 - 4.1e-170 566.7 0.0 5e-170 566.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AMP-binding PF00501.23 ETS64033.1 - 9.8e-48 162.5 0.0 1.5e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 ETS64033.1 - 1.3e-12 47.7 0.6 2.9e-12 46.6 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 ETS64033.1 - 7.5e-12 44.1 3.6 0.00037 19.8 0.0 7.2 8 0 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.1 ETS64033.1 - 2.6e-09 37.8 2.3 3.7e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 ETS64033.1 - 0.036 13.6 10.2 7.5 6.2 0.2 5.3 5 1 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 ETS64033.1 - 0.78 8.1 0.0 14 4.0 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Peptidase_M1 PF01433.15 ETS64035.1 - 6.8e-108 361.2 1.5 1e-68 232.2 0.1 2.2 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 ETS64035.1 - 4.2e-61 206.9 0.8 7.3e-61 206.1 0.6 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 ETS64035.1 - 3e-14 53.1 0.0 7.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily SKN1 PF03935.10 ETS64039.1 - 1.6e-188 626.9 4.4 2e-188 626.6 3.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 ETS64039.1 - 0.0017 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Neurensin PfkB PF00294.19 ETS64040.1 - 1.7e-60 204.7 4.4 1.9e-60 204.5 3.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 ETS64040.1 - 5.1e-06 25.8 0.0 1.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HAD_2 PF13419.1 ETS64040.1 - 0.029 14.5 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SNF2_N PF00176.18 ETS64041.1 - 1.8e-65 220.6 0.0 2.5e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 ETS64041.1 - 1.5e-29 102.0 0.0 2.7e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 ETS64041.1 - 7.8e-12 44.8 0.0 1.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 ETS64041.1 - 4e-05 23.3 12.4 6.7e-05 22.6 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS64041.1 - 0.00011 21.8 11.5 0.00019 21.0 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS64041.1 - 0.00023 21.1 13.2 0.00039 20.3 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS64041.1 - 0.0036 16.9 12.8 0.0062 16.1 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cupin_8 PF13621.1 ETS64042.1 - 1.6e-13 50.7 0.0 7.5e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETS64042.1 - 1.9e-08 34.5 0.6 1.4e-07 31.7 0.0 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 ETS64042.1 - 0.0011 18.3 0.0 0.0036 16.6 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 ETS64042.1 - 0.11 12.0 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Cupin domain F-box-like PF12937.2 ETS64042.1 - 0.16 11.7 2.4 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 F-box-like Sugar_tr PF00083.19 ETS64043.1 - 2.1e-38 132.0 18.1 2.1e-20 72.7 4.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS64043.1 - 5.1e-17 61.6 44.7 2.7e-08 32.9 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Raptor_N PF14538.1 ETS64044.1 - 1.4e-61 206.8 0.0 4.3e-61 205.2 0.0 1.9 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 ETS64044.1 - 5.6e-11 41.8 3.0 0.3 11.0 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.17 ETS64044.1 - 6.1e-06 25.8 6.4 0.03 14.4 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat BBS2_Mid PF14783.1 ETS64044.1 - 6.2e-06 25.9 0.0 0.0028 17.4 0.0 2.8 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 ETS64044.1 - 0.63 10.3 4.7 1.1 9.5 0.1 3.6 3 1 2 5 5 5 0 HEAT repeats WD40 PF00400.27 ETS64045.1 - 2.8e-23 80.8 5.9 7.2e-10 38.3 0.2 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 ETS64045.1 - 2e-20 72.4 0.1 4.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 ETS64045.1 - 0.00015 21.5 0.0 0.0019 17.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Zip PF02535.17 ETS64046.1 - 4.5e-26 91.5 41.3 2.4e-22 79.3 28.6 3.5 1 1 0 1 1 1 1 ZIP Zinc transporter CHD5 PF04420.9 ETS64047.1 - 6.5e-43 146.1 1.2 9.3e-43 145.6 0.8 1.2 1 0 0 1 1 1 1 CHD5-like protein DivIC PF04977.10 ETS64047.1 - 0.01 15.3 0.1 0.042 13.3 0.1 2.1 1 1 0 1 1 1 1 Septum formation initiator RCC1_2 PF13540.1 ETS64048.1 - 1.8e-13 49.6 11.7 3.3e-08 32.9 1.2 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETS64048.1 - 1.8e-10 40.8 0.4 0.077 13.2 0.0 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.17 ETS64049.1 - 8e-13 47.8 0.1 2.1e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64049.1 - 3.8e-11 42.6 0.0 5.8e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64049.1 - 2.2e-09 37.1 0.1 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 ETS64050.1 - 5.3e-15 55.4 0.0 2.1e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS64050.1 - 6.6e-08 32.8 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain Myb_DNA-binding PF00249.26 ETS64050.1 - 2.7e-07 30.5 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Abhydrolase_6 PF12697.2 ETS64051.1 - 3.7e-18 66.2 0.0 5.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS64051.1 - 2.7e-08 33.6 0.2 5.6e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS64051.1 - 0.0011 18.6 0.1 0.01 15.4 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS64051.1 - 0.057 12.6 0.4 0.8 8.8 0.2 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 ETS64051.1 - 0.086 12.7 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase 4HBT PF03061.17 ETS64052.1 - 3.1e-08 33.6 0.0 4.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 ETS64052.1 - 1.7e-05 25.2 0.0 2.9e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 ETS64052.1 - 2.4e-05 23.4 0.0 0.061 12.2 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase zf-CCCH_2 PF14608.1 ETS64052.1 - 3.8 7.6 5.9 0.72 9.9 0.2 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3635 PF12330.3 ETS64053.1 - 2.7e-14 53.0 0.0 2.5e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 ETS64053.1 - 0.0012 18.0 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64053.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1682 PF07946.9 ETS64053.1 - 0.36 9.6 4.6 0.8 8.4 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_L1 PF00687.16 ETS64054.1 - 1.6e-21 76.6 0.0 1.2e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family GARS_A PF01071.14 ETS64055.1 - 2.7e-71 239.1 0.0 3.9e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 ETS64055.1 - 3.1e-31 107.7 0.0 1.1e-30 106.0 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 ETS64055.1 - 1e-30 106.7 0.0 2.3e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 ETS64055.1 - 2.3e-27 95.0 0.1 4.8e-27 93.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 ETS64055.1 - 8.1e-17 61.2 0.3 3.2e-16 59.3 0.2 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.9 ETS64055.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Alba PF01918.16 ETS64055.1 - 0.093 12.3 0.1 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Alba CPSase_L_D2 PF02786.12 ETS64055.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Pyr_redox PF00070.22 ETS64056.1 - 7.2e-15 55.1 0.1 4.5e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS64056.1 - 9.8e-11 41.8 0.2 1.9e-05 24.6 0.2 4.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS64056.1 - 1.6e-05 25.0 0.7 1 9.4 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.2 ETS64056.1 - 0.0082 15.9 0.8 0.13 11.9 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family K_oxygenase PF13434.1 ETS64056.1 - 0.012 14.5 0.4 0.52 9.1 0.0 2.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 ETS64056.1 - 0.019 13.6 0.1 2 6.9 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 ETS64056.1 - 0.061 12.2 0.0 0.51 9.1 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.9 ETS64056.1 - 0.094 11.1 0.1 9.7 4.5 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein MFS_1 PF07690.11 ETS64059.1 - 2.1e-26 92.4 32.2 5.7e-26 91.0 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Corona_nucleoca PF00937.13 ETS64059.1 - 0.35 9.7 11.0 0.48 9.3 7.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PCI PF01399.22 ETS64060.1 - 6.9e-21 74.5 0.8 1.5e-20 73.4 0.6 1.6 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 ETS64060.1 - 4.9e-11 42.5 0.1 9.3e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 ETS64060.1 - 0.037 13.6 0.4 0.22 11.1 0.0 2.5 3 0 0 3 3 3 0 TPR repeat Peptidase_M18 PF02127.10 ETS64061.1 - 1.4e-160 534.5 0.0 1.9e-160 534.1 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Acyltransferase PF01553.16 ETS64061.1 - 8.7e-20 70.5 0.0 1.9e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Peptidase_M42 PF05343.9 ETS64061.1 - 0.0017 17.2 0.0 0.99 8.1 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase MarR PF01047.17 ETS64061.1 - 0.035 13.8 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 MarR family IBN_N PF03810.14 ETS64062.1 - 4.9e-08 32.7 0.0 1.2e-06 28.2 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 ETS64062.1 - 9.9e-05 22.1 2.5 1.1 9.5 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat CAS_CSE1 PF03378.10 ETS64062.1 - 0.00024 19.5 0.0 0.03 12.6 0.0 2.8 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus Tyrosinase PF00264.15 ETS64064.1 - 7.5e-36 124.3 1.5 1.1e-35 123.8 1.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Diphtheria_R PF01324.14 ETS64065.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, R domain Dioxygenase_C PF00775.16 ETS64066.1 - 4.2e-09 35.9 0.1 8.7e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase NmrA PF05368.8 ETS64068.1 - 4.9e-46 156.8 0.1 5.9e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS64068.1 - 3.7e-14 53.1 0.2 7.1e-14 52.2 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS64068.1 - 1.6e-05 23.7 0.0 2.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 ETS64068.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain VHS PF00790.14 ETS64069.1 - 7e-39 132.6 4.7 1e-38 132.1 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 ETS64069.1 - 4.8e-17 61.6 10.7 9.2e-17 60.7 7.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 ETS64069.1 - 1.3e-05 24.3 5.6 0.0079 15.6 0.3 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 ETS64069.1 - 0.0034 17.2 4.4 0.0066 16.3 3.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.16 ETS64069.1 - 0.028 14.3 3.2 0.056 13.3 2.2 1.4 1 0 0 1 1 1 0 IBR domain ENTH PF01417.15 ETS64069.1 - 0.033 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 ENTH domain zf-RING_5 PF14634.1 ETS64069.1 - 1.7 8.4 9.8 3.2 7.5 6.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RNA_pol_Rpb1_1 PF04997.7 ETS64070.1 - 5.3e-111 371.1 0.0 7.2e-111 370.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 ETS64070.1 - 3.7e-103 344.5 0.1 5.4e-103 344.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 ETS64070.1 - 2.6e-66 222.6 0.0 5.1e-66 221.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 ETS64070.1 - 3.6e-60 202.9 0.1 1.2e-59 201.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 ETS64070.1 - 1.7e-46 157.2 1.3 1.7e-46 157.2 0.9 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 ETS64070.1 - 1.9e-45 154.4 0.0 3.5e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 ETS64070.1 - 1.8e-36 124.1 0.0 4e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 ETS64070.1 - 8.8e-17 59.6 183.7 0.012 15.6 6.4 13.7 10 1 5 15 15 15 14 RNA polymerase Rpb1 C-terminal repeat RhoGAP PF00620.22 ETS64071.1 - 1e-46 158.3 0.8 1.1e-45 154.9 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 ETS64071.1 - 3.6e-15 55.7 30.3 5.3e-09 36.0 5.4 3.4 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 ETS64071.1 - 5.7e-07 29.1 7.7 5.7e-07 29.1 5.3 4.1 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rotamase_2 PF13145.1 ETS64071.1 - 2.4 8.8 10.0 2.4 8.8 0.8 3.3 3 0 0 3 3 3 0 PPIC-type PPIASE domain Ras PF00071.17 ETS64072.1 - 4.8e-66 221.1 0.0 5.8e-66 220.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS64072.1 - 3.1e-19 69.6 0.0 4.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS64072.1 - 5.3e-14 51.8 0.0 6.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS64072.1 - 1e-06 28.1 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS64072.1 - 1.3e-05 24.7 0.1 3.3e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS64072.1 - 4e-05 23.5 0.0 0.00014 21.7 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS64072.1 - 0.0011 18.2 0.0 0.014 14.6 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 ETS64072.1 - 0.0031 16.7 0.0 0.0039 16.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 ETS64072.1 - 0.023 14.6 0.2 0.05 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETS64072.1 - 0.036 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS64072.1 - 0.042 14.0 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS64072.1 - 0.056 12.6 0.0 0.083 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 ETS64072.1 - 0.058 13.6 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETS64072.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 ETS64072.1 - 0.096 11.6 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin Tox-PLDMTX PF15645.1 ETS64072.1 - 0.11 12.5 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold MCM PF00493.18 ETS64072.1 - 0.13 11.0 0.0 0.37 9.5 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family AAA_5 PF07728.9 ETS64072.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) U3_assoc_6 PF08640.6 ETS64073.1 - 1.1e-22 79.5 0.4 3.3e-22 78.0 0.1 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 ETS64073.1 - 0.0023 18.4 6.2 3.2 8.6 0.0 5.6 3 1 1 4 4 4 2 Tetratricopeptide repeat IFT20 PF14931.1 ETS64073.1 - 0.084 12.7 0.4 0.31 10.9 0.3 1.9 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 NRDE-2 PF08424.5 ETS64073.1 - 0.27 10.0 6.1 1.8 7.3 0.0 3.6 4 0 0 4 4 4 0 NRDE-2, necessary for RNA interference ATP11 PF06644.6 ETS64074.1 - 1.1e-81 274.2 2.0 1.4e-81 273.9 1.4 1.1 1 0 0 1 1 1 1 ATP11 protein Nefa_Nip30_N PF10187.4 ETS64074.1 - 4.1 7.6 9.2 1.6 8.9 1.2 2.8 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 ABC_membrane PF00664.18 ETS64075.1 - 5.7e-46 157.1 13.4 2.6e-22 79.5 1.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 ETS64075.1 - 2.3e-44 151.0 0.0 2.3e-25 89.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS64075.1 - 1.6e-09 37.3 0.6 7.4e-05 22.0 0.0 4.0 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS64075.1 - 4.8e-07 30.0 0.2 2.4 8.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 ETS64075.1 - 4.3e-06 26.2 0.2 0.019 14.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 ETS64075.1 - 1.6e-05 24.3 0.2 0.063 12.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS64075.1 - 1.8e-05 24.8 0.8 0.97 9.5 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 ETS64075.1 - 2.6e-05 24.2 2.6 0.033 14.1 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 ETS64075.1 - 0.00017 21.9 0.0 0.91 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS64075.1 - 0.00031 19.7 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 ETS64075.1 - 0.0013 18.1 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 ETS64075.1 - 0.0045 16.6 0.3 0.45 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 ETS64075.1 - 0.0047 16.6 0.7 4.1 7.0 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 ETS64075.1 - 0.006 16.4 0.5 4.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 ETS64075.1 - 0.0061 16.1 0.1 3.1 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETS64075.1 - 0.011 16.1 0.1 5.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 ETS64075.1 - 0.011 15.1 2.2 0.044 13.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 ETS64075.1 - 0.017 15.0 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 ETS64075.1 - 0.018 14.7 2.5 0.34 10.6 0.1 3.6 3 0 0 3 3 2 0 Part of AAA domain AAA_17 PF13207.1 ETS64075.1 - 0.024 15.4 4.9 2.5 8.9 1.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETS64075.1 - 0.036 13.9 0.1 3.9 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 ETS64075.1 - 0.045 12.9 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 ETS64075.1 - 0.049 13.0 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 ETS64075.1 - 0.081 12.7 0.2 0.27 11.0 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_14 PF13173.1 ETS64075.1 - 0.13 12.1 0.2 15 5.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 ETS64075.1 - 0.17 11.3 0.2 56 3.1 0.0 3.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 ETS64075.1 - 0.19 11.2 2.6 2.2 7.7 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 ETS64075.1 - 0.22 10.3 0.1 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 ETS64075.1 - 0.26 10.9 0.0 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 ETS64075.1 - 0.32 11.2 5.0 11 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 ETS64075.1 - 0.36 10.0 0.1 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.10 ETS64075.1 - 0.44 10.2 2.4 15 5.2 0.0 2.7 3 0 0 3 3 2 0 NTPase Asp PF00026.18 ETS64076.1 - 8.8e-42 143.4 0.0 1.8e-41 142.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS64076.1 - 2.3e-08 34.1 1.5 1.7e-07 31.3 0.3 2.6 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS64076.1 - 1.1e-06 29.0 0.1 0.044 14.2 0.0 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 ETS64076.1 - 0.00016 21.2 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 ETS64076.1 - 0.008 15.9 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease PhoD PF09423.5 ETS64078.1 - 2.2e-40 138.5 0.0 8.3e-40 136.6 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase Herpes_capsid PF06112.6 ETS64078.1 - 0.028 14.4 2.7 0.1 12.6 1.8 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein NADH_B2 PF14813.1 ETS64079.1 - 0.0022 17.6 0.7 0.0042 16.7 0.5 1.4 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 E1_dh PF00676.15 ETS64080.1 - 9.4e-112 372.5 0.3 1.2e-111 372.2 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 ETS64080.1 - 0.0012 17.8 0.1 0.002 17.1 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 ETS64080.1 - 0.0042 16.6 2.6 0.0042 16.6 1.8 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Nucleoporin_C PF03177.9 ETS64081.1 - 2.8e-101 339.8 5.3 3.5e-101 339.5 3.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 ETS64081.1 - 1.2e-38 132.9 0.0 1.7e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like BC10 PF06726.7 ETS64081.1 - 0.051 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 Adenylsucc_synt PF00709.16 ETS64082.1 - 9.2e-163 541.7 0.0 1e-162 541.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glu_synthase PF01645.12 ETS64084.1 - 3.3e-160 533.0 0.0 6.3e-160 532.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 ETS64084.1 - 6.7e-137 456.0 0.0 9.5e-137 455.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 ETS64084.1 - 2.3e-119 397.9 0.0 7.9e-119 396.1 0.0 1.9 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 ETS64084.1 - 6.2e-66 221.2 0.6 1e-65 220.5 0.4 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 ETS64084.1 - 3.4e-22 78.1 0.1 7.3e-22 77.0 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 ETS64084.1 - 9.5e-15 55.0 0.0 2.9e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS64084.1 - 4.7e-11 43.1 0.1 6.4e-05 23.0 0.1 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS64084.1 - 3.4e-09 36.5 0.9 9.5e-09 35.1 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS64084.1 - 6.9e-09 35.9 0.1 4.2e-05 23.8 0.0 3.3 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS64084.1 - 1.2e-06 27.3 2.1 6.7e-06 24.8 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 ETS64084.1 - 3.8e-06 26.0 0.8 0.013 14.3 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 ETS64084.1 - 8.7e-06 25.0 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 ETS64084.1 - 2e-05 23.6 3.9 0.00024 20.0 0.2 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 ETS64084.1 - 2.8e-05 23.1 2.7 0.00015 20.7 0.2 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETS64084.1 - 0.00011 21.4 5.6 0.0013 17.8 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS64084.1 - 0.00069 19.2 0.0 0.27 10.7 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 ETS64084.1 - 0.0011 19.2 0.1 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FMN_dh PF01070.13 ETS64084.1 - 0.0019 17.1 1.0 0.011 14.6 0.6 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase AdoHcyase_NAD PF00670.16 ETS64084.1 - 0.0026 17.6 1.8 0.75 9.6 0.2 3.4 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Thi4 PF01946.12 ETS64084.1 - 0.0042 16.2 1.0 0.018 14.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 ETS64084.1 - 0.0094 15.0 0.4 0.022 13.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 ETS64084.1 - 0.032 13.9 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 ETS64084.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Shikimate_DH PF01488.15 ETS64084.1 - 0.069 13.2 0.2 20 5.2 0.1 2.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 ETS64084.1 - 0.076 11.2 0.2 1.4 7.0 0.0 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 ETS64084.1 - 0.11 11.4 0.5 1.1 8.1 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 ETS64084.1 - 0.13 11.9 0.2 0.34 10.5 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 ETS64084.1 - 0.17 11.2 1.1 0.81 9.0 0.1 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain MFS_1 PF07690.11 ETS64085.1 - 2e-29 102.4 54.7 9.6e-28 96.9 20.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily NIR_SIR PF01077.17 ETS64086.1 - 3.7e-30 104.3 0.1 6.7e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 ETS64086.1 - 1.1e-23 84.1 0.0 5.8e-23 81.8 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 ETS64086.1 - 4.4e-14 52.2 3.2 5.9e-12 45.4 1.8 2.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.22 ETS64086.1 - 2.1e-12 47.2 1.7 4.2e-12 46.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.12 ETS64086.1 - 2.5e-12 46.2 0.0 5.5e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.1 ETS64086.1 - 4.5e-12 45.6 0.0 1.4e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 ETS64086.1 - 1.3e-09 37.5 0.2 4e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.1 ETS64086.1 - 3e-05 23.8 0.8 0.47 10.2 0.0 3.6 2 2 2 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS64086.1 - 0.00013 22.1 2.1 0.015 15.4 0.1 3.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS64086.1 - 0.062 12.1 2.6 0.24 10.2 0.2 2.6 1 1 1 2 2 2 0 FAD binding domain TrkA_N PF02254.13 ETS64086.1 - 0.12 12.3 1.0 3.9 7.5 0.1 2.9 3 0 0 3 3 3 0 TrkA-N domain Oxidored_molyb PF00174.14 ETS64087.1 - 7.7e-52 175.1 0.0 1.8e-51 173.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 ETS64087.1 - 6.7e-44 148.6 0.1 1.2e-43 147.8 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 ETS64087.1 - 1.1e-28 99.9 0.0 2.2e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 ETS64087.1 - 2.6e-22 78.3 0.2 8e-22 76.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 ETS64087.1 - 1.3e-21 76.5 0.0 6.5e-21 74.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETS64087.1 - 0.013 15.3 0.0 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF1137 PF06587.6 ETS64087.1 - 0.049 13.2 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) Ribosomal_L3 PF00297.17 ETS64088.1 - 1.3e-120 401.7 8.1 1.6e-120 401.4 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 CybS PF05328.7 ETS64089.1 - 1e-44 151.4 0.0 1.6e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 CybS Brix PF04427.13 ETS64090.1 - 6.3e-54 182.5 0.0 9.2e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF2072 PF09845.4 ETS64090.1 - 8.5 6.3 9.6 31 4.4 6.7 2.0 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Zn_clus PF00172.13 ETS64091.1 - 3.6e-08 33.1 6.8 3.6e-08 33.1 4.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 ETS64092.1 - 2.3e-05 24.2 14.0 3.8 7.5 0.1 8.1 6 3 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS64092.1 - 0.073 12.8 2.9 14 5.7 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 ETS64092.1 - 0.076 12.7 12.6 0.073 12.8 0.3 5.7 7 1 1 8 8 8 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 ETS64092.1 - 1.4 9.0 20.4 8.6 6.5 0.0 8.3 11 0 0 11 11 11 0 Tetratricopeptide repeat HAT PF02184.11 ETS64092.1 - 6.3 6.6 9.0 3 7.6 0.0 5.1 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat Ribonuc_2-5A PF06479.7 ETS64093.1 - 2.2e-47 160.1 0.2 3.6e-47 159.4 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 ETS64093.1 - 2.9e-41 141.3 0.0 4.6e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64093.1 - 4.2e-19 68.6 0.0 1.1e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 ETS64093.1 - 5.7e-07 29.2 0.6 5.8e-05 22.6 0.0 2.7 2 1 1 3 3 3 1 PQQ-like domain PQQ PF01011.16 ETS64093.1 - 1.5e-05 24.3 0.0 0.00054 19.3 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.1 ETS64093.1 - 0.019 15.2 0.3 6.8 7.1 0.0 4.0 3 1 0 3 3 3 0 PQQ-like domain Kdo PF06293.9 ETS64093.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_gE PF02480.11 ETS64093.1 - 0.057 11.6 0.5 0.36 9.0 0.1 2.3 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E YrbL-PhoP_reg PF10707.4 ETS64093.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4006 PF13179.1 ETS64093.1 - 0.074 12.6 0.6 0.18 11.3 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) UIM PF02809.15 ETS64093.1 - 0.54 9.9 4.7 0.11 12.0 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif RTC PF01137.16 ETS64094.1 - 8.8e-58 194.7 0.0 1.2e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 ETS64094.1 - 4.3e-30 103.7 0.0 7.8e-30 102.9 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HTH_13 PF11972.3 ETS64094.1 - 0.089 12.6 0.2 0.78 9.6 0.0 2.6 3 0 0 3 3 3 0 HTH DNA binding domain BPL_N PF09825.4 ETS64095.1 - 1.2e-80 271.0 0.0 2.1e-79 266.9 0.0 2.2 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 ETS64095.1 - 5.3e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 ETS64095.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 1 1 0 1 1 1 0 Biotin protein ligase C terminal domain ArsA_ATPase PF02374.10 ETS64096.1 - 3e-110 368.0 0.3 3.4e-110 367.8 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 ETS64096.1 - 6.9e-15 54.9 0.0 1.1e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETS64096.1 - 7.6e-08 32.4 0.0 3.1e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 ETS64096.1 - 1.9e-05 24.0 0.2 0.00011 21.5 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 ETS64096.1 - 4.4e-05 23.0 0.2 0.00048 19.6 0.1 2.4 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 ETS64096.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.5 1 1 0 1 1 1 1 YhjQ protein AAA_19 PF13245.1 ETS64096.1 - 0.0072 16.0 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 ETS64096.1 - 0.0076 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.1 ETS64096.1 - 0.0095 15.3 0.4 0.052 12.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 ETS64096.1 - 0.022 13.8 0.1 0.053 12.6 0.1 1.7 1 1 1 2 2 2 0 ATPase MipZ NB-ARC PF00931.17 ETS64096.1 - 0.031 13.1 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF972 PF06156.8 ETS64096.1 - 0.043 14.1 1.0 0.11 12.8 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_24 PF13479.1 ETS64096.1 - 0.088 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETS64096.1 - 0.092 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Erf4 PF10256.4 ETS64097.1 - 3.4e-35 120.4 0.0 8.1e-35 119.2 0.0 1.7 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_C PF01191.14 ETS64097.1 - 1.1e-31 108.2 0.2 2.4e-31 107.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain KH_1 PF00013.24 ETS64097.1 - 1.3e-30 104.8 0.6 2.4e-09 36.7 0.0 6.0 6 0 0 6 6 6 4 KH domain RNA_pol_Rpb5_N PF03871.9 ETS64097.1 - 3.4e-30 104.2 0.9 7e-30 103.2 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain KH_3 PF13014.1 ETS64097.1 - 3.3e-22 77.6 0.8 3.9e-07 29.5 0.1 5.8 6 0 0 6 6 6 4 KH domain Mrr_cat PF04471.7 ETS64097.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease SRR1 PF07985.7 ETS64098.1 - 2.5e-13 49.7 0.0 2.6e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 SRR1 DUF1180 PF06679.7 ETS64098.1 - 1.3 8.8 5.0 7 6.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Nse4_C PF08743.5 ETS64099.1 - 3.5e-21 75.0 0.0 6.7e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 ETS64099.1 - 2.5e-13 49.6 1.0 2.5e-13 49.6 0.7 2.2 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Ras PF00071.17 ETS64100.1 - 2.5e-41 140.7 0.6 3.3e-41 140.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETS64100.1 - 4.9e-10 38.9 0.1 5.7e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETS64100.1 - 2.7e-09 37.5 0.0 5.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETS64100.1 - 0.00069 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IDO PF01231.13 ETS64101.1 - 8.9e-148 492.2 0.0 1.1e-147 491.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ACPS PF01648.15 ETS64101.1 - 3.3e-10 39.7 0.0 5.2e-09 35.9 0.0 2.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Peptidase_S49 PF01343.13 ETS64101.1 - 0.048 13.4 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 DUF974 PF06159.8 ETS64102.1 - 2.1e-66 223.9 0.0 2.8e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Cellulase PF00150.13 ETS64103.1 - 1.7e-11 43.8 0.0 2.1e-06 27.1 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Tocopherol_cycl PF14249.1 ETS64104.1 - 0.00068 18.4 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 Tocopherol cyclase Fcf1 PF04900.7 ETS64106.1 - 4.2e-25 87.7 0.7 4.2e-25 87.7 0.5 1.9 2 0 0 2 2 2 1 Fcf1 DNA_pol_viral_N PF00242.12 ETS64106.1 - 7.5 5.4 14.1 17 4.2 7.5 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Dynactin PF12455.3 ETS64107.1 - 3.2e-79 265.7 0.6 3.2e-79 265.7 0.4 2.8 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 ETS64107.1 - 7.1e-21 73.6 1.0 1.3e-20 72.8 0.4 1.6 2 0 0 2 2 2 1 CAP-Gly domain ATG16 PF08614.6 ETS64107.1 - 0.00064 19.5 17.1 0.00064 19.5 11.9 6.1 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) UCR_TM PF02921.9 ETS64108.1 - 3.4e-19 68.8 2.5 6.6e-19 67.9 1.7 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 ETS64108.1 - 2.1e-16 59.2 0.1 3.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SOR_SNZ PF01680.12 ETS64109.1 - 3e-112 373.2 5.3 4.3e-112 372.7 3.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 ETS64109.1 - 2.7e-06 26.6 9.0 5.1e-06 25.7 0.1 2.8 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 ETS64109.1 - 0.006 15.5 0.3 0.082 11.8 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 ETS64109.1 - 0.008 15.2 0.0 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 ETS64109.1 - 0.02 14.0 0.2 0.02 14.0 0.1 2.3 2 1 1 3 3 3 0 Nitronate monooxygenase Dus PF01207.12 ETS64109.1 - 0.033 13.0 0.3 0.71 8.6 0.0 2.3 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 ETS64109.1 - 0.044 13.0 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF2267 PF10025.4 ETS64109.1 - 0.052 13.6 0.0 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF2946 PF11162.3 ETS64110.1 - 0.026 14.7 3.9 0.047 13.8 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Hormone_recep PF00104.25 ETS64111.1 - 0.1 11.7 0.1 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Orai-1 PF07856.7 ETS64112.1 - 0.064 12.8 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Mediator of CRAC channel activity Clathrin PF00637.15 ETS64113.1 - 1.6e-12 47.2 0.0 0.00035 20.1 0.0 3.3 3 0 0 3 3 3 3 Region in Clathrin and VPS Mito_carr PF00153.22 ETS64113.1 - 0.00049 19.7 0.2 0.0082 15.8 0.0 3.1 3 0 0 3 3 3 1 Mitochondrial carrier protein zf-RING_5 PF14634.1 ETS64113.1 - 0.016 14.9 5.9 0.026 14.2 4.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS64113.1 - 0.053 13.5 5.7 0.093 12.7 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS64113.1 - 0.19 11.5 7.0 0.38 10.6 4.9 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.1 ETS64113.1 - 0.51 10.1 5.6 0.91 9.3 3.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 ETS64113.1 - 2 8.6 5.0 4.2 7.5 3.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger JTB PF05439.7 ETS64114.1 - 0.0012 18.6 3.7 0.0073 16.0 0.4 2.2 1 1 1 2 2 2 2 Jumping translocation breakpoint protein (JTB) SAP25 PF15476.1 ETS64115.1 - 0.034 13.6 1.5 0.061 12.8 1.0 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 RNA12 PF10443.4 ETS64116.1 - 7.1e-145 482.7 0.8 9.2e-145 482.4 0.6 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 ETS64116.1 - 3.9e-06 26.4 0.0 3.8e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 ETS64116.1 - 4.6e-05 23.2 0.1 0.00035 20.3 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 ETS64116.1 - 0.00024 21.1 1.7 0.0085 16.1 0.5 3.3 2 1 0 2 2 2 1 AAA ATPase domain RRM_5 PF13893.1 ETS64116.1 - 0.00068 19.4 0.0 0.0035 17.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 ETS64116.1 - 0.0036 17.1 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain RRM_6 PF14259.1 ETS64116.1 - 0.014 15.4 0.0 0.058 13.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NB-ARC PF00931.17 ETS64116.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain tRNA-synt_2b PF00587.20 ETS64117.1 - 9.2e-44 149.0 0.0 1.4e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS64117.1 - 1.9e-11 43.7 0.1 8.7e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Anticodon binding domain Nic96 PF04097.9 ETS64118.1 - 2.7e-183 610.4 0.2 4e-183 609.8 0.1 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Cation_efflux PF01545.16 ETS64118.1 - 2.3e-31 108.9 2.3 4e-31 108.1 1.6 1.4 1 0 0 1 1 1 1 Cation efflux family Na_H_Exchanger PF00999.16 ETS64119.1 - 3.2e-62 210.2 37.2 3.2e-62 210.2 25.8 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4366 PF14283.1 ETS64119.1 - 0.091 12.1 0.3 2.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Glucosamine_iso PF01182.15 ETS64120.1 - 2.3e-66 223.3 0.0 2.7e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ras PF00071.17 ETS64121.1 - 4.7e-32 110.6 0.0 7e-30 103.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETS64121.1 - 1.4e-12 48.1 0.0 3.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS64121.1 - 1.6e-06 27.4 0.0 3.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS64121.1 - 5.2e-05 22.4 0.0 8.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS64121.1 - 0.0027 17.6 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS64121.1 - 0.0055 16.1 0.0 0.095 12.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETS64121.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PIP5K PF01504.13 ETS64122.1 - 4.6e-84 281.4 0.0 6.6e-84 280.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CENP-H PF05837.7 ETS64123.1 - 3.4e-07 30.4 5.2 3.4e-07 30.4 3.6 3.0 1 1 1 3 3 3 1 Centromere protein H (CENP-H) TFIIA PF03153.8 ETS64123.1 - 0.0093 15.9 9.6 0.013 15.4 6.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Thaumatin PF00314.12 ETS64124.1 - 0.00011 21.8 0.1 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Thaumatin family Avl9 PF09794.4 ETS64126.1 - 2.1e-140 467.5 0.0 2.6e-140 467.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 ETS64126.1 - 2.2e-10 40.3 0.0 0.00022 20.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 ETS64126.1 - 1.9e-09 37.1 0.1 4.4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.7 ETS64126.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking uDENN PF03456.13 ETS64126.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 uDENN domain AIF-MLS PF14962.1 ETS64126.1 - 6.2 6.4 14.7 16 5.0 10.2 1.6 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Fibrillarin PF01269.12 ETS64127.1 - 7.8e-108 358.6 0.0 9.8e-108 358.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 ETS64127.1 - 9.9e-06 25.2 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 ETS64127.1 - 0.0099 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS64127.1 - 0.053 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tubulin PF00091.20 ETS64128.1 - 1.2e-74 250.8 0.0 2.3e-74 249.8 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS64128.1 - 6.5e-44 149.0 0.0 1.3e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETS64128.1 - 8.1e-07 29.1 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETS64128.1 - 0.0096 15.3 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain TAF PF02969.12 ETS64129.1 - 5.5e-27 93.5 0.4 1e-26 92.6 0.3 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 ETS64129.1 - 2.2e-12 46.9 0.0 7.1e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 ETS64129.1 - 7.5e-06 25.9 0.8 1.4e-05 25.0 0.5 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 ETS64129.1 - 0.025 14.3 0.1 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MSP1_C PF07462.6 ETS64129.1 - 0.22 9.8 0.7 0.41 8.9 0.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus LSM PF01423.17 ETS64130.1 - 7.4e-12 44.6 0.0 1.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 ETS64130.1 - 5.2e-05 23.0 0.0 6.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain tRNA-synt_1b PF00579.20 ETS64131.1 - 1.9e-21 76.4 0.0 1.8e-20 73.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3860 PF12976.2 ETS64131.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Pkinase PF00069.20 ETS64133.1 - 8.2e-42 143.1 0.2 2.5e-23 82.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64133.1 - 5.7e-11 41.9 0.2 1.3e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS64133.1 - 0.27 9.9 0.1 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 ETS64133.1 - 0.28 10.4 0.1 0.5 9.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family BRCT PF00533.21 ETS64135.1 - 0.0035 17.4 0.0 0.0084 16.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Tmemb_cc2 PF10267.4 ETS64135.1 - 0.019 13.5 8.6 0.022 13.3 4.8 1.9 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SAGA-Tad1 PF12767.2 ETS64136.1 - 2.9e-50 171.2 1.8 2.2e-49 168.4 0.2 2.5 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.27 ETS64137.1 - 7.7e-19 66.8 11.0 2.4e-05 24.0 0.0 7.2 7 1 0 7 7 7 3 WD domain, G-beta repeat DUF3639 PF12341.3 ETS64137.1 - 3.9e-05 23.5 1.2 0.0067 16.3 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3639) eIF2A PF08662.6 ETS64137.1 - 0.057 13.1 0.0 1.6 8.4 0.0 2.8 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A R3H PF01424.17 ETS64138.1 - 6.2e-13 48.2 0.0 1.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 ETS64138.1 - 2.4e-06 27.3 58.7 4.1e-05 23.4 8.7 14.3 16 1 1 17 17 17 8 NF-X1 type zinc finger FancD2 PF14631.1 ETS64138.1 - 8.6 3.3 6.0 12 2.8 4.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Abhydrolase_5 PF12695.2 ETS64139.1 - 3.1e-08 33.4 0.1 2e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 ETS64139.1 - 7.2e-05 21.6 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS64139.1 - 0.0041 16.7 0.1 0.0086 15.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS64139.1 - 0.0052 16.0 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETS64139.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1903 PF08991.5 ETS64141.1 - 2.1e-28 98.2 4.9 3e-28 97.7 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 ETS64141.1 - 0.91 9.5 5.3 1.6 8.7 3.7 1.5 1 0 0 1 1 1 0 CHCH domain Med26 PF08711.6 ETS64142.1 - 1.7e-07 30.5 0.0 4.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sulfate_transp PF00916.15 ETS64143.1 - 3.6e-42 144.2 2.1 6.4e-42 143.4 1.4 1.4 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 ETS64143.1 - 1.4e-15 56.8 0.0 3.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 ETS64143.1 - 3.3e-08 32.9 0.0 6.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain WD40 PF00400.27 ETS64144.1 - 4.2e-49 162.7 3.3 1.4e-09 37.4 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 ETS64144.1 - 4.1e-46 156.6 0.1 4.1e-46 156.6 0.1 3.7 2 2 0 2 2 2 1 Striatin family Nucleoporin_N PF08801.6 ETS64144.1 - 7.1e-06 25.0 0.0 0.016 14.0 0.0 3.3 3 0 0 3 3 3 2 Nup133 N terminal like PAN_3 PF08277.7 ETS64144.1 - 0.008 15.7 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 PAN-like domain BTB PF00651.26 ETS64145.1 - 4.5e-10 39.5 0.2 0.00029 20.8 0.0 3.6 3 1 0 3 3 3 3 BTB/POZ domain MATH PF00917.21 ETS64145.1 - 0.13 12.5 0.9 2.4 8.4 0.6 2.3 1 1 0 1 1 1 0 MATH domain DUF2414 PF10309.4 ETS64146.1 - 4.1e-09 35.9 0.0 6.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) R3H PF01424.17 ETS64147.1 - 2.7e-12 46.1 0.1 6.3e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 ETS64147.1 - 5.3e-11 42.3 0.0 2.1e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS64147.1 - 6.1e-08 32.1 0.2 1.5e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64147.1 - 7.6e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mur_ligase_M PF08245.7 ETS64147.1 - 0.00011 22.3 0.0 0.65 10.0 0.0 2.7 2 1 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 ETS64147.1 - 0.078 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Cyclase PF04199.8 ETS64148.1 - 5.1e-13 49.0 0.1 1.3e-12 47.7 0.1 1.7 1 1 0 1 1 1 1 Putative cyclase Perilipin PF03036.11 ETS64148.1 - 0.048 12.5 1.7 0.07 11.9 1.2 1.2 1 0 0 1 1 1 0 Perilipin family ABC_tran PF00005.22 ETS64149.1 - 1.2e-46 158.4 0.2 1.1e-21 77.6 0.0 3.3 3 1 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 ETS64149.1 - 6.7e-24 83.5 4.0 6.7e-24 83.5 2.8 3.8 4 1 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 ETS64149.1 - 4.1e-17 63.0 0.1 0.0015 18.5 0.0 4.4 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 ETS64149.1 - 6.4e-11 41.9 0.3 0.0013 17.9 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS64149.1 - 1.5e-08 34.0 0.4 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS64149.1 - 3.8e-08 34.1 0.6 0.0091 16.8 0.0 4.4 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 ETS64149.1 - 5.7e-08 32.7 0.0 0.0026 17.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.1 ETS64149.1 - 1.3e-06 28.5 0.6 0.15 12.2 0.0 3.9 4 1 0 4 4 3 2 AAA domain NACHT PF05729.7 ETS64149.1 - 1.7e-06 27.8 0.2 0.0035 17.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 ETS64149.1 - 2.8e-06 27.8 0.0 0.072 13.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 ETS64149.1 - 3.2e-06 26.6 0.0 0.024 14.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS64149.1 - 7.7e-06 25.1 0.0 0.063 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 ETS64149.1 - 1.2e-05 24.9 2.4 0.03 13.7 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_16 PF13191.1 ETS64149.1 - 3.2e-05 24.0 5.5 0.021 14.8 0.3 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 ETS64149.1 - 7.5e-05 23.0 0.5 1.5 9.1 0.0 3.8 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 ETS64149.1 - 7.8e-05 22.4 0.0 0.07 12.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ETS64149.1 - 0.00024 20.9 0.0 0.96 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 ETS64149.1 - 0.00026 21.2 0.0 0.3 11.3 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 ETS64149.1 - 0.00043 20.2 6.4 0.048 13.6 0.2 3.3 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 ETS64149.1 - 0.00052 20.1 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 ETS64149.1 - 0.00089 19.1 4.2 0.44 10.4 0.0 3.9 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 ETS64149.1 - 0.0019 17.0 0.2 1.4 7.6 0.0 2.6 2 0 0 2 2 2 2 ArgK protein Gly-zipper_OmpA PF13436.1 ETS64149.1 - 0.0033 17.0 5.4 0.0079 15.8 3.8 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain FtsK_SpoIIIE PF01580.13 ETS64149.1 - 0.0085 15.5 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MutS_V PF00488.16 ETS64149.1 - 0.018 14.4 0.1 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 MutS domain V DUF87 PF01935.12 ETS64149.1 - 0.022 14.5 4.4 0.12 12.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_23 PF13476.1 ETS64149.1 - 0.029 14.7 0.0 0.029 14.7 0.0 4.7 4 1 0 5 5 4 0 AAA domain Med7 PF05983.6 ETS64149.1 - 0.031 14.0 0.2 0.072 12.8 0.1 1.6 1 0 0 1 1 1 0 MED7 protein NB-ARC PF00931.17 ETS64149.1 - 0.038 12.8 0.1 7.1 5.3 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 ETS64149.1 - 0.04 12.9 0.8 13 4.6 0.0 3.3 4 0 0 4 4 3 0 AAA ATPase domain cobW PF02492.14 ETS64149.1 - 0.058 12.8 0.0 11 5.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 ETS64149.1 - 0.061 13.1 4.6 0.61 9.8 0.0 3.2 4 0 0 4 4 3 0 Dynamin family PduV-EutP PF10662.4 ETS64149.1 - 0.064 12.7 0.1 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 ETS64149.1 - 0.08 12.4 0.3 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 ETS64149.1 - 0.091 12.6 9.7 0.3 10.9 0.0 3.6 4 1 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 ETS64149.1 - 0.099 12.3 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 ETS64149.1 - 0.12 11.9 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 ETS64149.1 - 0.69 9.5 3.8 16 5.0 0.0 3.0 4 0 0 4 4 2 0 Archaeal ATPase AAA_5 PF07728.9 ETS64149.1 - 1.3 8.7 5.6 16 5.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) NAD_binding_1 PF00175.16 ETS64150.1 - 1.5e-25 89.8 0.0 3.3e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS64150.1 - 3.2e-19 68.8 0.0 5.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETS64150.1 - 5.8e-05 23.0 0.0 0.00041 20.2 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS64150.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain TrbE PF11100.3 ETS64151.1 - 0.25 11.2 1.7 0.5 10.2 1.1 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbE UCH PF00443.24 ETS64152.1 - 2.3e-43 148.2 0.0 3.4e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS64152.1 - 2.6e-10 40.2 0.0 4e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SUZ PF12752.2 ETS64153.1 - 1e-14 54.7 5.5 1e-14 54.7 3.8 4.7 3 2 0 3 3 3 1 SUZ domain R3H PF01424.17 ETS64153.1 - 1.5e-08 34.1 0.7 3.3e-08 33.1 0.5 1.5 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.15 ETS64154.1 - 1.4e-12 47.5 0.2 3.2e-12 46.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Acyl-CoA_dh_1 PF00441.19 ETS64155.1 - 1.2e-31 109.8 1.7 1.7e-31 109.3 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS64155.1 - 7.8e-17 60.5 0.2 1.3e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS64155.1 - 4.3e-11 43.3 0.0 1.9e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS64155.1 - 1.3e-08 35.1 0.7 1.9e-08 34.6 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.24 ETS64156.1 - 2e-42 144.5 0.0 6.4e-42 142.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS64156.1 - 1e-23 82.9 0.0 3.1e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETS64156.1 - 1.9e-05 23.5 0.1 4.4e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS64156.1 - 9.6e-05 22.2 0.6 0.004 17.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 ETS64156.1 - 0.35 9.9 7.9 0.88 8.5 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF1675 PF07897.6 ETS64156.1 - 5.4 6.8 13.4 10 5.9 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Ras PF00071.17 ETS64158.1 - 1.1e-53 180.9 0.0 1.3e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS64158.1 - 2e-15 57.3 0.0 3.6e-15 56.5 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS64158.1 - 4.1e-07 29.4 0.0 7.2e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS64158.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 ETS64158.1 - 0.11 11.9 0.3 1.2 8.6 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ssu72 PF04722.8 ETS64159.1 - 9.1e-77 256.8 0.0 1.1e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 ETS64159.1 - 0.013 15.8 0.3 0.047 14.0 0.1 1.9 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Herpes_UL25 PF01499.11 ETS64160.1 - 0.033 12.5 0.9 0.035 12.4 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Gcd10p PF04189.8 ETS64161.1 - 1.3e-86 290.4 0.0 3.3e-86 289.1 0.0 1.6 2 0 0 2 2 2 1 Gcd10p family CDC27 PF09507.5 ETS64163.1 - 8.1e-79 265.8 58.7 1.8e-77 261.4 40.7 2.5 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DEAD PF00270.24 ETS64164.1 - 2.9e-32 111.4 0.8 1.1e-31 109.5 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pyr_redox_2 PF07992.9 ETS64164.1 - 3.5e-28 98.8 0.0 7.8e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Helicase_C PF00271.26 ETS64164.1 - 4e-26 90.6 0.2 9.3e-26 89.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyr_redox PF00070.22 ETS64164.1 - 6.6e-18 64.9 0.7 7.6e-15 55.0 0.0 3.6 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS64164.1 - 1.3e-07 31.9 0.7 0.0017 18.4 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS64164.1 - 2.5e-05 23.4 0.1 0.00032 19.8 0.0 2.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 ETS64164.1 - 6e-05 22.9 0.1 0.0017 18.3 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 ETS64164.1 - 0.00032 19.8 0.4 0.26 10.3 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS64164.1 - 0.00067 18.6 0.7 0.019 13.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Helicase_C_2 PF13307.1 ETS64164.1 - 0.0025 17.8 0.0 0.0068 16.3 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain K_oxygenase PF13434.1 ETS64164.1 - 0.0029 16.5 0.2 0.082 11.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS64164.1 - 0.0036 16.2 0.0 0.023 13.6 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 ETS64164.1 - 0.0096 16.1 1.3 0.16 12.2 0.0 3.3 3 0 0 3 3 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 ETS64164.1 - 0.013 13.9 0.2 0.04 12.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein AAA_30 PF13604.1 ETS64164.1 - 0.015 14.8 0.1 0.089 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain GIDA PF01134.17 ETS64164.1 - 0.016 14.0 5.9 0.018 13.9 0.1 3.1 4 0 0 4 4 4 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 ETS64164.1 - 0.02 13.5 0.0 0.14 10.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 ETS64164.1 - 0.032 14.3 0.4 7.5 6.6 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 ETS64165.1 - 1.6e-30 103.8 3.4 4.2e-06 26.4 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 ETS64165.1 - 0.038 13.4 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Aldedh PF00171.17 ETS64166.1 - 3e-121 404.9 0.1 3.6e-121 404.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Viral_env_E26 PF11050.3 ETS64166.1 - 0.024 13.8 0.0 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 Virus envelope protein E26 DSPc PF00782.15 ETS64167.1 - 0.0002 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 ETS64167.1 - 0.00025 21.1 0.0 0.00079 19.4 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 ETS64167.1 - 0.0043 17.3 0.2 0.035 14.3 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETS64167.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase JAB PF01398.16 ETS64168.1 - 8.9e-29 99.5 0.2 3.4e-28 97.6 0.1 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 ETS64168.1 - 9.8e-07 28.3 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 ETS64168.1 - 0.027 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Cyclin_N PF00134.18 ETS64169.1 - 1.1e-45 154.3 0.4 7.3e-43 145.1 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETS64169.1 - 2e-32 111.5 0.2 2e-32 111.5 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain UvrD-helicase PF00580.16 ETS64171.1 - 1.3e-14 54.2 0.0 6.6e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 ETS64171.1 - 2.2e-12 47.1 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 ETS64171.1 - 1.6e-10 41.0 0.0 4.9e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 ETS64171.1 - 1.3e-08 34.6 0.2 0.071 12.6 0.0 3.6 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 ETS64171.1 - 1.2e-07 31.5 1.2 0.0026 17.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 ETS64171.1 - 7.4e-06 25.6 0.2 0.00011 21.8 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 ETS64171.1 - 0.00013 22.1 0.1 0.12 12.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 ETS64171.1 - 0.00069 18.9 0.0 0.076 12.2 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_12 PF13087.1 ETS64171.1 - 0.0065 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF3597 PF12200.3 ETS64171.1 - 0.022 15.1 1.3 0.022 15.1 0.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) BolA PF01722.13 ETS64172.1 - 1.2e-19 70.0 0.0 2.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein CN_hydrolase PF00795.17 ETS64173.1 - 1.1e-08 34.6 0.0 1.4e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Actin PF00022.14 ETS64177.1 - 7.1e-36 123.4 0.0 1.4e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Actin CHCH PF06747.8 ETS64178.1 - 6e-09 35.5 3.4 8.4e-09 35.1 2.4 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 ETS64178.1 - 0.0083 16.1 3.1 0.027 14.5 2.2 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Copper-fist PF00649.13 ETS64178.1 - 0.04 13.1 0.6 0.067 12.3 0.4 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain Cmc1 PF08583.5 ETS64178.1 - 0.063 13.0 3.7 0.63 9.8 2.8 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 ETS64178.1 - 0.35 10.7 2.6 1.5 8.7 0.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 ETS64178.1 - 1.2 9.1 5.3 7.1 6.7 0.6 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) zf-MYND PF01753.13 ETS64179.1 - 5.7e-12 45.3 10.4 5.7e-12 45.3 7.2 3.2 3 1 0 3 3 3 1 MYND finger SET PF00856.23 ETS64179.1 - 5.1e-10 39.8 0.0 1.3e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-Mss51 PF13824.1 ETS64179.1 - 0.72 9.7 8.8 4.6 7.1 1.8 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 RNA_pol_3_Rpc31 PF11705.3 ETS64180.1 - 3e-06 27.3 5.1 6.3e-06 26.3 3.6 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HEAT_2 PF13646.1 ETS64180.1 - 7.8e-05 22.8 21.4 0.00029 21.0 0.1 6.4 5 2 1 6 6 6 2 HEAT repeats Anticodon_1 PF08264.8 ETS64180.1 - 0.008 15.9 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Pox_Ag35 PF03286.9 ETS64180.1 - 0.027 13.9 6.6 0.058 12.9 4.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 ETS64180.1 - 0.15 10.8 6.6 0.28 9.9 4.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Myc_N PF01056.13 ETS64180.1 - 0.4 9.7 8.3 2.8 7.0 2.9 2.3 2 0 0 2 2 2 0 Myc amino-terminal region RXT2_N PF08595.6 ETS64180.1 - 3.6 7.3 10.6 14 5.4 6.1 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIF_alpha PF05793.7 ETS64180.1 - 4.6 5.4 18.9 8.6 4.6 13.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 ETS64180.1 - 5.7 7.3 18.6 19 5.6 12.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.24 ETS64181.1 - 3.3e-07 29.8 14.2 5.7e-07 29.1 9.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS64181.1 - 0.0013 17.9 6.6 0.0024 17.1 4.6 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 ETS64181.1 - 0.091 13.0 0.0 0.091 13.0 0.0 5.4 3 2 0 3 3 3 0 SET domain AMP-binding PF00501.23 ETS64182.1 - 3.6e-82 276.0 0.0 4.9e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MRG PF05712.8 ETS64183.1 - 1.4e-53 180.7 0.0 3.2e-53 179.5 0.0 1.5 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 ETS64183.1 - 2.2e-09 36.8 0.2 4.8e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 ETS64183.1 - 0.29 10.8 3.2 0.23 11.1 0.9 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Tht1 PF04163.7 ETS64184.1 - 0.05 12.0 2.6 0.085 11.2 0.0 2.0 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein Septin PF00735.13 ETS64185.1 - 6.6e-125 415.7 0.8 1.2e-124 414.9 0.6 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 ETS64185.1 - 2.7e-07 30.5 0.0 5.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETS64185.1 - 2.3e-06 26.9 0.0 6.3e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 ETS64185.1 - 8.2e-05 22.1 0.2 0.0024 17.3 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETS64185.1 - 0.0001 22.1 3.9 0.065 13.0 0.0 3.2 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 ETS64185.1 - 0.0003 20.1 1.4 0.0044 16.4 0.0 2.7 2 1 0 2 2 2 1 Ras family AAA_10 PF12846.2 ETS64185.1 - 0.0013 18.2 0.1 0.0043 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 ETS64185.1 - 0.002 18.2 0.1 0.014 15.5 0.0 2.3 3 1 0 3 3 3 1 AAA domain AIG1 PF04548.11 ETS64185.1 - 0.0023 17.0 0.8 0.0051 15.9 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Arch_ATPase PF01637.13 ETS64185.1 - 0.003 17.2 1.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 ETS64185.1 - 0.0063 16.8 8.4 0.02 15.1 1.0 2.6 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 ETS64185.1 - 0.0074 16.7 0.1 0.06 13.8 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 ETS64185.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS64185.1 - 0.02 14.8 0.2 0.094 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 ETS64185.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 ETS64185.1 - 0.062 12.7 0.3 9.6 5.6 0.0 3.1 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 ETS64185.1 - 0.12 11.9 1.7 0.13 11.8 0.0 2.0 3 0 0 3 3 2 0 AAA domain Exonuc_VII_L PF02601.10 ETS64185.1 - 0.13 11.4 7.9 0.16 11.1 4.6 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phage_GPO PF05929.6 ETS64185.1 - 0.15 11.3 4.3 0.29 10.3 3.0 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YlqD PF11068.3 ETS64185.1 - 0.2 11.6 7.2 0.51 10.3 5.0 1.7 1 0 0 1 1 1 0 YlqD protein IncA PF04156.9 ETS64185.1 - 0.38 10.3 7.6 0.76 9.3 5.3 1.4 1 0 0 1 1 1 0 IncA protein ATP_bind_1 PF03029.12 ETS64185.1 - 0.4 10.1 2.5 19 4.6 0.0 3.2 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 ETS64185.1 - 2.5 8.3 11.7 54 4.0 8.1 2.3 1 1 0 1 1 1 0 AAA domain AdoHcyase PF05221.12 ETS64186.1 - 3e-136 452.6 0.0 3.5e-136 452.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 ETS64186.1 - 4.3e-85 283.5 3.3 6.3e-85 282.9 2.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS64186.1 - 1.6e-10 40.4 0.0 3.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 ETS64186.1 - 0.00031 20.1 0.1 0.00048 19.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 ETS64186.1 - 0.0018 18.2 0.1 0.004 17.1 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 ETS64186.1 - 0.042 12.9 0.5 0.2 10.7 0.4 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4448 PF14610.1 ETS64186.1 - 0.052 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) NAD_binding_7 PF13241.1 ETS64186.1 - 0.079 13.2 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_M24 PF00557.19 ETS64187.1 - 7.6e-42 143.2 0.0 1.2e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ETS64187.1 - 1.2e-23 84.0 0.0 7.4e-22 78.2 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain TPR_14 PF13428.1 ETS64189.1 - 6.1 7.7 13.6 16 6.5 1.0 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat IDO PF01231.13 ETS64190.1 - 1.2e-40 139.2 0.0 2e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Ank_2 PF12796.2 ETS64191.1 - 2.2e-29 101.6 3.8 2.5e-15 56.5 0.2 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS64191.1 - 1.2e-21 75.2 2.4 2.4e-08 33.3 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETS64191.1 - 3.2e-20 72.1 1.1 8.1e-14 51.6 0.4 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS64191.1 - 1.7e-17 63.0 4.0 4.4e-10 39.4 0.2 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS64191.1 - 8.8e-15 53.3 2.0 0.00063 19.7 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Pro_isomerase PF00160.16 ETS64192.1 - 1.5e-47 161.6 0.2 1.7e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD La PF05383.12 ETS64194.1 - 1.7e-20 72.5 0.0 7.3e-20 70.5 0.0 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 ETS64194.1 - 5.8e-08 32.2 0.4 1.9e-07 30.6 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64194.1 - 2.4e-06 27.4 0.2 7.9e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS64194.1 - 7.4e-05 22.5 0.3 0.0048 16.7 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.1 ETS64194.1 - 0.0028 17.4 0.1 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dabb PF07876.7 ETS64194.1 - 0.013 15.8 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain adh_short PF00106.20 ETS64195.1 - 7.2e-21 74.8 0.8 6.2e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS64195.1 - 4.5e-12 45.9 0.5 7.9e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 ETS64195.1 - 1.2e-07 31.9 0.5 2.7e-07 30.7 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 ETS64195.1 - 1.3e-05 24.3 0.1 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 ETS64195.1 - 0.00037 20.8 0.2 0.00097 19.5 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.1 ETS64195.1 - 0.0006 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 ETS64195.1 - 0.00067 19.3 0.3 0.0012 18.5 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 ETS64195.1 - 0.0071 15.3 0.2 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase YjeF_N PF03853.10 ETS64195.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Helicase_RecD PF05127.9 ETS64195.1 - 0.025 14.2 0.2 0.043 13.4 0.2 1.3 1 0 0 1 1 1 0 Helicase NAD_binding_2 PF03446.10 ETS64195.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 ETS64195.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 ETS64195.1 - 0.036 13.4 0.0 0.083 12.3 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS64195.1 - 0.044 12.6 0.0 0.059 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 ETS64195.1 - 0.054 13.2 1.0 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 ETS64195.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding COG2 PF06148.6 ETS64196.1 - 1.6e-37 128.3 0.1 4.9e-37 126.7 0.1 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 ETS64196.1 - 7.1e-06 26.1 0.0 8.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 ETS64196.1 - 0.014 15.1 0.1 0.036 13.9 0.1 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Tombus_movement PF05318.7 ETS64196.1 - 0.35 11.5 1.5 0.76 10.4 0.3 2.1 2 0 0 2 2 2 0 Tombusvirus movement protein Pkinase PF00069.20 ETS64197.1 - 7.4e-69 231.7 0.0 1.5e-68 230.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64197.1 - 2e-49 168.0 0.0 3.4e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS64197.1 - 0.00077 18.5 0.0 0.0029 16.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Mito_carr PF00153.22 ETS64198.1 - 1e-53 179.0 4.9 6.2e-19 67.4 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Lactococcin PF04369.8 ETS64198.1 - 0.022 14.6 0.4 9.1 6.2 0.0 3.3 3 0 0 3 3 3 0 Lactococcin-like family SURF4 PF02077.10 ETS64199.1 - 1.5e-93 313.0 4.7 1.7e-93 312.8 3.3 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_M28 PF04389.12 ETS64201.1 - 3.6e-33 114.8 0.0 7.6e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 ETS64201.1 - 0.00023 20.7 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 ETS64201.1 - 0.051 12.3 0.0 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Fungal_trans PF04082.13 ETS64202.1 - 1.2e-18 66.9 0.0 2.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS64202.1 - 1.9e-07 30.8 8.9 3.6e-07 29.9 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 ETS64202.1 - 0.26 10.8 4.0 0.51 9.8 2.8 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Glyco_hydro_47 PF01532.15 ETS64203.1 - 2.2e-148 494.6 0.0 4.3e-148 493.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TRAPPC-Trs85 PF12739.2 ETS64203.1 - 1.8e-96 323.3 0.1 3.1e-96 322.5 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Foie-gras_1 PF11817.3 ETS64203.1 - 0.0058 16.1 1.0 0.012 15.0 0.7 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 GATA PF00320.22 ETS64205.1 - 2.3e-28 97.2 15.5 5.4e-15 54.4 2.5 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 ETS64205.1 - 2.5e-09 36.5 0.8 5e-09 35.5 0.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 ETS64205.1 - 7.8e-05 21.9 3.5 0.027 13.8 0.4 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 ETS64205.1 - 0.0026 17.5 4.1 0.056 13.2 3.0 2.6 1 1 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 ETS64205.1 - 0.052 13.5 0.9 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 ETS64205.1 - 0.098 12.2 4.6 0.13 11.8 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger eIF-5_eIF-2B PF01873.12 ETS64205.1 - 0.15 11.7 3.8 7.6 6.2 0.2 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RRN7 PF11781.3 ETS64205.1 - 1.8 8.1 7.6 0.94 9.0 0.6 2.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 ETS64205.1 - 2.1 7.6 9.4 1.2 8.4 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbon domain DUF572 PF04502.8 ETS64207.1 - 1.3e-40 139.6 1.6 1.4e-40 139.5 1.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) CALCOCO1 PF07888.6 ETS64207.1 - 0.0088 14.3 3.5 0.01 14.1 2.4 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like SGL PF08450.7 ETS64207.1 - 0.046 13.1 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region DUF3147 PF11345.3 ETS64210.1 - 0.085 12.8 2.0 0.16 11.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) RNB PF00773.14 ETS64211.1 - 1.9e-89 300.1 0.0 2.6e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 ETS64211.1 - 6.6e-09 35.9 1.4 3.7e-08 33.5 1.0 2.2 1 1 0 1 1 1 1 PIN domain OB_RNB PF08206.6 ETS64211.1 - 0.012 15.1 0.0 0.046 13.2 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain DSPc PF00782.15 ETS64212.1 - 1.1e-18 67.0 0.4 1.3e-15 57.1 0.5 2.8 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS64212.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF904 PF06005.7 ETS64212.1 - 1.8 8.9 6.2 3.9 7.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) AA_permease PF00324.16 ETS64213.1 - 2.1e-111 372.6 36.2 2.6e-111 372.3 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS64213.1 - 5.6e-34 117.4 39.4 7.5e-34 116.9 27.3 1.2 1 0 0 1 1 1 1 Amino acid permease DFP PF04127.10 ETS64214.1 - 1.4e-18 67.2 0.0 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein zf-H2C2_2 PF13465.1 ETS64215.1 - 1.6e-08 34.4 0.6 1.6e-08 34.4 0.4 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 ETS64215.1 - 5.9e-07 29.4 10.7 7.2e-06 26.0 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETS64215.1 - 2.6e-05 23.9 2.5 0.14 12.0 0.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETS64215.1 - 0.0008 19.5 0.4 0.0008 19.5 0.3 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 ETS64215.1 - 0.072 13.3 3.1 4.8 7.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Whi5 PF08528.6 ETS64216.1 - 0.2 11.3 0.5 0.34 10.5 0.4 1.4 1 0 0 1 1 1 0 Whi5 like PINIT PF14324.1 ETS64217.1 - 6.4e-28 97.6 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 ETS64217.1 - 7.4e-21 73.4 7.9 1.3e-20 72.6 5.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 ETS64217.1 - 0.00015 21.1 1.7 0.00032 20.1 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 ETS64217.1 - 1.3 8.9 6.8 2.4 8.0 4.7 1.4 1 0 0 1 1 1 0 Ring finger domain RNase_T PF00929.19 ETS64218.1 - 2.6e-19 70.1 0.0 5.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF543 PF04418.7 ETS64219.1 - 2.5e-25 88.1 0.2 6.5e-25 86.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Peroxidase_2 PF01328.12 ETS64219.1 - 2.4e-11 42.8 0.0 4.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 DUF883 PF05957.8 ETS64219.1 - 0.013 15.8 5.7 0.22 11.9 2.6 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SAGA-Tad1 PF12767.2 ETS64219.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit MT0933_antitox PF14013.1 ETS64219.1 - 5.4 7.1 13.9 11 6.2 9.6 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein AA_permease PF00324.16 ETS64220.1 - 5e-115 384.5 44.8 6e-115 384.3 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS64220.1 - 7.8e-35 120.2 48.9 9.6e-35 119.9 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease Ctr PF04145.10 ETS64221.1 - 2e-40 138.1 1.9 2e-40 138.1 1.3 1.4 2 0 0 2 2 2 1 Ctr copper transporter family Sensor PF13796.1 ETS64221.1 - 0.014 15.0 2.6 0.074 12.6 0.1 2.1 2 0 0 2 2 2 0 Putative sensor Ferric_reduct PF01794.14 ETS64222.1 - 6.7e-21 74.6 15.4 7.2e-21 74.5 7.5 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS64222.1 - 1.1e-13 50.9 0.0 2.3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 ETS64222.1 - 1.4e-13 51.0 0.0 2.1e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETS64222.1 - 1.4e-07 31.9 0.0 2.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS64222.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain OAD_gamma PF04277.8 ETS64222.1 - 0.14 12.5 0.1 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Xan_ur_permease PF00860.15 ETS64223.1 - 2.1e-60 204.2 38.3 3e-60 203.7 26.1 1.5 1 1 0 1 1 1 1 Permease family dCMP_cyt_deam_1 PF00383.17 ETS64225.1 - 6e-13 48.3 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 ETS64225.1 - 0.087 12.5 0.5 0.28 10.9 0.1 1.9 1 1 1 2 2 2 0 Xanthomonas XOO_2897-like deaminase DIOX_N PF14226.1 ETS64226.1 - 1.3e-20 74.0 0.0 2.2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS64226.1 - 4e-16 59.1 0.3 7.4e-16 58.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.21 ETS64227.1 - 2.4e-46 156.6 0.0 2.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS64227.1 - 0.0013 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 ETS64227.1 - 0.0088 15.7 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 ETS64227.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain PKD_channel PF08016.7 ETS64228.1 - 0.084 11.2 10.9 0.76 8.1 7.6 2.2 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans PF00520.26 ETS64228.1 - 1.6 7.9 24.4 74 2.4 16.4 3.0 1 1 1 2 2 2 0 Ion transport protein Stig1 PF04885.8 ETS64230.1 - 0.01 16.0 0.4 0.013 15.7 0.3 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 zf-CCHC_3 PF13917.1 ETS64230.1 - 0.039 13.6 1.3 0.039 13.6 0.9 2.1 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 ETS64230.1 - 0.47 10.1 4.9 0.24 11.1 1.5 1.9 2 0 0 2 2 2 0 Zinc knuckle Zn_clus PF00172.13 ETS64231.1 - 9.8e-07 28.5 10.7 9.8e-07 28.5 7.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIE_alpha PF02002.12 ETS64232.1 - 2.2e-11 43.1 1.7 4e-11 42.3 0.7 1.7 2 0 0 2 2 2 1 TFIIE alpha subunit DASH_Dam1 PF08653.5 ETS64232.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 Glycos_transf_4 PF00953.16 ETS64233.1 - 3e-34 118.1 4.4 9.2e-34 116.5 3.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 4 SKG6 PF08693.5 ETS64233.1 - 0.019 14.3 1.1 0.019 14.3 0.8 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PH PF00169.24 ETS64234.1 - 8.9e-08 32.2 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF2664 PF10867.3 ETS64234.1 - 2.6 8.7 6.3 10 6.8 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) adh_short PF00106.20 ETS64235.1 - 3.7e-20 72.5 4.7 4e-20 72.4 2.6 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS64235.1 - 7.1e-18 65.2 0.1 1e-17 64.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS64235.1 - 4.8e-08 32.8 4.7 2.1e-07 30.7 3.2 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS64235.1 - 1e-05 25.6 1.1 2e-05 24.6 0.8 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS64235.1 - 0.00039 19.9 0.4 0.00066 19.1 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CRAL_TRIO PF00650.15 ETS64236.1 - 1.5e-18 66.8 0.0 2.3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2841 PF11001.3 ETS64237.1 - 4.2e-39 133.2 0.2 7.5e-39 132.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) TFIIA_gamma_C PF02751.9 ETS64238.1 - 1.5e-23 82.3 0.9 1.9e-23 81.9 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 ETS64238.1 - 3.6e-16 58.4 0.1 5.3e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DJ-1_PfpI PF01965.19 ETS64239.1 - 1.5e-27 95.8 0.4 2.2e-27 95.3 0.0 1.4 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 ETS64239.1 - 8e-16 57.7 0.1 1.7e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 ETS64239.1 - 0.0018 17.9 0.1 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 ETS64239.1 - 0.0061 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family Yae1_N PF09811.4 ETS64240.1 - 4.9e-14 51.5 0.9 1.1e-13 50.4 0.6 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal WEMBL PF05701.6 ETS64240.1 - 0.025 13.0 3.9 0.038 12.4 2.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF2611 PF11022.3 ETS64241.1 - 7.6e-19 67.5 2.2 1.8e-18 66.3 1.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) Pyr_redox_2 PF07992.9 ETS64242.1 - 1.8e-20 73.7 0.0 3e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS64242.1 - 5.7e-14 52.2 0.0 1.5e-08 34.8 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 ETS64242.1 - 3.6e-12 44.6 3.2 1e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETS64242.1 - 2.8e-11 43.3 0.3 9.4e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETS64242.1 - 1.3e-09 37.1 2.8 0.00018 21.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETS64242.1 - 1e-08 34.1 3.2 0.00038 19.6 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETS64242.1 - 1.2e-06 28.0 2.6 0.0074 15.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.1 ETS64242.1 - 7.1e-05 22.9 0.0 0.51 10.3 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS64242.1 - 0.014 15.1 0.0 13 5.5 0.0 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 ETS64242.1 - 0.02 15.1 0.6 1 9.6 0.0 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding SWIRM PF04433.12 ETS64242.1 - 0.16 12.1 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 SWIRM domain Rer1 PF03248.8 ETS64243.1 - 1.5e-84 281.9 0.1 1.7e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Rer1 family 2TM PF13239.1 ETS64243.1 - 0.59 10.2 2.7 3.7 7.6 0.1 2.2 2 0 0 2 2 2 0 2TM domain MgsA_C PF12002.3 ETS64244.1 - 8.9e-51 171.9 0.0 1.6e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 ETS64244.1 - 1e-14 54.1 0.0 2.9e-13 49.4 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 ETS64244.1 - 2.9e-14 53.4 0.0 1.1e-13 51.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETS64244.1 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS64244.1 - 4.3e-07 30.1 1.3 3.3e-06 27.2 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 ETS64244.1 - 4.9e-07 29.9 1.1 0.00019 21.4 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETS64244.1 - 4.2e-06 26.5 0.2 2.1e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS64244.1 - 3.3e-05 23.1 0.2 0.061 12.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 ETS64244.1 - 5.5e-05 23.2 0.1 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 ETS64244.1 - 0.00037 21.2 0.0 0.001 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS64244.1 - 0.0005 19.7 0.1 0.0019 17.9 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 ETS64244.1 - 0.0006 20.1 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 ETS64244.1 - 0.0012 18.3 0.1 0.77 9.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.1 ETS64244.1 - 0.0022 17.6 0.0 0.0063 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETS64244.1 - 0.0023 17.3 1.0 0.0085 15.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS64244.1 - 0.0038 16.7 0.4 1.2 8.4 0.0 2.6 2 1 0 2 2 2 1 AAA-like domain AAA_28 PF13521.1 ETS64244.1 - 0.0043 17.0 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sgf11 PF08209.6 ETS64244.1 - 0.0047 16.1 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) IstB_IS21 PF01695.12 ETS64244.1 - 0.0048 16.3 0.2 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 ETS64244.1 - 0.0058 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 ETS64244.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.9 ETS64244.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 ETS64244.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 ETS64244.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 ETS64244.1 - 0.021 14.4 0.1 0.38 10.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 ETS64244.1 - 0.023 14.3 0.1 2.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 ETS64244.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS64244.1 - 0.036 14.2 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 ETS64244.1 - 0.069 12.7 0.1 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 ETS64244.1 - 0.08 12.5 0.1 0.71 9.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 ETS64244.1 - 0.08 12.1 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.10 ETS64244.1 - 0.14 10.7 0.0 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 ETS64244.1 - 0.16 10.7 0.0 0.44 9.3 0.0 1.7 1 1 1 2 2 2 0 NB-ARC domain RRM_6 PF14259.1 ETS64245.1 - 9.9e-09 35.0 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS64245.1 - 1.2e-07 31.2 0.0 2.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64245.1 - 0.00086 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.17 ETS64246.1 - 1.4e-118 396.1 0.1 1.7e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS64246.1 - 0.0099 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1338 PF07063.8 ETS64247.1 - 6e-79 265.2 0.0 7.8e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Transp_cyt_pur PF02133.10 ETS64248.1 - 6.7e-131 436.8 38.1 7.8e-131 436.6 26.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.17 ETS64249.1 - 2.8e-74 250.3 0.0 4e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BPL_LplA_LipB PF03099.14 ETS64250.1 - 8.9e-16 58.0 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FAR1 PF03101.10 ETS64252.1 - 2.3e-06 28.0 0.1 4.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 ETS64252.1 - 0.0061 16.7 0.0 0.021 15.0 0.0 2.0 1 0 0 1 1 1 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 ETS64252.1 - 0.029 13.9 0.0 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 MuDR family transposase TFIIA PF03153.8 ETS64252.1 - 1.2 8.9 23.3 1.4 8.7 4.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.18 ETS64252.1 - 2 8.5 10.0 0.068 13.1 1.9 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF605 PF04652.11 ETS64252.1 - 7 5.9 36.8 3.3 6.9 4.4 2.2 2 0 0 2 2 2 0 Vta1 like Acyltransferase PF01553.16 ETS64253.1 - 0.0022 17.4 0.0 0.045 13.1 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase PAN_4 PF14295.1 ETS64254.1 - 2.7e-05 23.7 2.2 5.6e-05 22.7 1.6 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 ETS64254.1 - 0.00076 18.7 0.3 0.0023 17.2 0.2 1.7 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 ETS64254.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 PAN domain DnaJ PF00226.26 ETS64255.1 - 2.1e-19 69.0 1.7 4.4e-19 67.9 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 ETS64255.1 - 0.0079 15.8 7.3 0.44 10.2 0.3 2.9 3 0 0 3 3 3 2 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 ETS64255.1 - 0.081 12.9 1.3 0.13 12.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF202 PF02656.10 ETS64256.1 - 5.6e-15 55.3 1.8 1.1e-14 54.3 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Herpes_UL37_2 PF07413.6 ETS64256.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 RCC1 PF00415.13 ETS64257.1 - 3.3e-24 84.8 0.0 3e-06 27.3 0.0 6.5 5 3 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS64257.1 - 2.2e-16 58.9 19.4 0.0002 20.8 0.3 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Lactamase_B_2 PF12706.2 ETS64260.1 - 1.7e-31 109.2 0.9 1.4e-30 106.3 0.8 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 ETS64260.1 - 1.3e-13 50.1 0.0 5e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 ETS64260.1 - 7.8e-09 35.4 2.8 1.8e-08 34.2 2.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Cyt-b5 PF00173.23 ETS64261.1 - 1.7e-22 78.9 0.1 1.7e-22 78.9 0.1 2.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 ETS64261.1 - 4.6e-10 39.8 17.9 4.6e-10 39.8 12.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PBS_linker_poly PF00427.16 ETS64261.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2404 PF10296.4 ETS64262.1 - 1.5e-07 31.4 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Glyco_hydro_16 PF00722.16 ETS64263.1 - 1.1e-16 60.6 1.2 2.4e-16 59.5 0.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 ETS64265.1 - 1.7e-47 161.6 4.6 1.7e-47 161.6 3.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS64265.1 - 2.8e-11 43.6 0.1 2.2e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS64265.1 - 0.00022 20.9 0.0 0.0067 16.1 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ETS64265.1 - 0.0058 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Atx10homo_assoc PF09759.4 ETS64266.1 - 3.5e-22 78.0 0.1 8.3e-19 67.2 0.0 4.1 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF2012 PF09430.5 ETS64267.1 - 2.1e-37 127.6 0.0 2.9e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 ETS64267.1 - 0.051 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain ERG4_ERG24 PF01222.12 ETS64268.1 - 4.6e-145 483.4 6.9 5.6e-145 483.1 4.8 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 ETS64268.1 - 1.8e-06 27.4 0.4 4.9e-06 26.0 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 ETS64268.1 - 6.6e-05 22.9 0.6 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 ETS64268.1 - 0.036 14.2 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ORC6 PF05460.8 ETS64268.1 - 4.3 6.3 10.9 5.8 5.9 7.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Zip PF02535.17 ETS64270.1 - 3.5e-42 144.5 1.7 5e-42 144.0 1.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.16 ETS64270.1 - 0.071 12.6 1.9 0.17 11.4 0.0 2.3 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DLH PF01738.13 ETS64271.1 - 2.9e-18 65.9 0.1 3.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS64271.1 - 0.00043 20.0 0.0 0.00081 19.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS64271.1 - 0.0029 17.5 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FadA PF09403.5 ETS64271.1 - 0.078 12.9 0.5 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Adhesion protein FadA adh_short PF00106.20 ETS64272.1 - 2.6e-20 73.0 1.2 3.3e-20 72.6 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS64272.1 - 5.4e-11 42.7 0.1 1.3e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS64272.1 - 1.2e-07 31.6 0.6 1.6e-07 31.1 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS64273.1 - 3.6e-32 111.4 0.0 7.5e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETS64273.1 - 8e-18 64.6 0.0 1.5e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.7 ETS64273.1 - 1.2e-05 24.8 0.1 6.2e-05 22.4 0.1 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NAD_Gly3P_dh_N PF01210.18 ETS64273.1 - 0.0059 16.3 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldl_recept_b PF00058.12 ETS64273.1 - 0.017 15.4 1.1 2.1 8.7 0.0 4.0 5 0 0 5 5 5 0 Low-density lipoprotein receptor repeat class B Arylesterase PF01731.15 ETS64273.1 - 0.073 13.0 0.0 1.5 8.8 0.0 2.9 4 0 0 4 4 4 0 Arylesterase NAD_binding_1 PF00175.16 ETS64274.1 - 1.8e-28 99.2 0.0 5.4e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS64274.1 - 1.6e-26 92.3 0.0 2.7e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 ETS64274.1 - 1.7e-21 75.7 0.0 2.3e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 ETS64274.1 - 7.9e-08 32.3 0.0 2e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS64274.1 - 0.0016 18.3 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain RTP801_C PF07809.6 ETS64274.1 - 0.076 12.6 0.0 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 RTP801 C-terminal region p450 PF00067.17 ETS64275.1 - 1.7e-70 237.8 0.0 2.1e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.8 ETS64277.1 - 5.9e-17 62.1 13.8 5.9e-17 62.1 9.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_4 PF08386.5 ETS64279.1 - 6.1e-16 58.1 0.0 1.3e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS64279.1 - 7e-09 35.5 0.0 2.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS64279.1 - 1.8e-07 31.2 5.3 8.3e-07 29.1 1.3 2.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS64279.1 - 0.006 16.3 0.0 0.038 13.7 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hep_59 PF07052.6 ETS64280.1 - 3e-24 85.3 0.5 3e-24 85.3 0.3 2.4 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Glutaredoxin PF00462.19 ETS64281.1 - 3.9e-12 45.9 0.0 7.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 ETS64281.1 - 0.0064 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS64281.1 - 0.094 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SBDS_C PF09377.5 ETS64282.1 - 1.3e-43 147.6 0.0 2.3e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 ETS64282.1 - 1.2e-32 111.4 1.3 3.2e-32 110.1 0.4 1.9 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PMT PF02366.13 ETS64283.1 - 3.5e-73 245.9 16.7 6.4e-73 245.1 11.6 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 ETS64283.1 - 2.5e-21 76.1 0.2 4.2e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 MIR domain WD40 PF00400.27 ETS64284.1 - 6.9e-60 196.9 9.6 2.6e-10 39.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 ETS64284.1 - 1.1e-12 46.9 6.5 2e-12 46.1 4.5 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 ETS64284.1 - 0.0002 19.6 3.5 0.093 10.8 0.5 3.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 ETS64284.1 - 0.0067 15.5 0.2 0.51 9.3 0.0 3.3 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF4178 PF13785.1 ETS64284.1 - 0.061 13.3 0.1 0.84 9.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4178) Bestrophin PF01062.16 ETS64285.1 - 2.3e-47 161.3 1.8 5.6e-46 156.8 1.2 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.13 ETS64286.1 - 0.00052 19.8 6.6 0.00097 19.0 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.19 ETS64287.1 - 1.1e-17 63.2 33.3 4.4e-05 23.0 0.5 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 ETS64287.1 - 1.2e-05 25.0 4.0 1.3e-05 24.9 0.9 2.7 2 0 0 2 2 2 1 Zinc knuckle Ribosomal_L24e PF01246.15 ETS64288.1 - 4.5e-29 100.1 3.0 1.2e-28 98.7 2.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Amino_oxidase PF01593.19 ETS64290.1 - 2.2e-58 198.4 0.0 2.7e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS64290.1 - 1.9e-14 53.4 0.2 5.8e-14 51.8 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS64290.1 - 5.1e-08 32.2 3.3 8.9e-07 28.1 2.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS64290.1 - 3.3e-06 27.4 0.4 1.6e-05 25.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS64290.1 - 4.1e-06 26.0 0.3 8.3e-06 25.0 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 ETS64290.1 - 4.3e-06 25.8 0.5 9.2e-06 24.7 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS64290.1 - 5e-06 26.7 0.1 0.00036 20.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS64290.1 - 1.6e-05 23.5 0.7 0.00022 19.7 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 ETS64290.1 - 0.00014 21.0 0.1 0.00021 20.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS64290.1 - 0.00015 20.9 1.1 0.00028 20.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETS64290.1 - 0.00034 19.5 0.5 0.024 13.5 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 ETS64290.1 - 0.0038 16.2 0.2 0.011 14.6 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS64290.1 - 0.0047 16.8 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS64290.1 - 0.005 16.6 0.1 0.36 10.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding ECR1_N PF14382.1 ETS64290.1 - 0.025 13.8 0.0 0.061 12.6 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region MFS_1 PF07690.11 ETS64292.1 - 4.3e-35 121.0 44.7 2e-34 118.8 31.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS64292.1 - 6.1e-13 48.1 8.9 6.1e-13 48.1 6.1 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 ETS64292.1 - 3.5e-08 32.1 18.2 6.4e-08 31.2 12.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nramp PF01566.13 ETS64293.1 - 1.7e-91 306.6 13.3 1.5e-50 172.0 0.9 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein DUF1996 PF09362.5 ETS64294.1 - 1.2e-67 228.0 0.0 1.6e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Zn_clus PF00172.13 ETS64295.1 - 0.0043 16.9 6.5 0.0077 16.1 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Parvo_coat_N PF08398.5 ETS64295.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Parvovirus coat protein VP1 PseudoU_synth_1 PF01416.15 ETS64296.1 - 6.1e-18 65.1 0.0 1.1e-07 32.1 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase EF-1_beta_acid PF10587.4 ETS64296.1 - 5.4 7.2 12.1 0.96 9.6 2.4 2.9 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region TPR_11 PF13414.1 ETS64297.1 - 4.7e-44 147.8 19.9 2.7e-16 58.9 0.3 5.4 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 ETS64297.1 - 1.1e-30 103.9 10.8 1.4e-05 24.4 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETS64297.1 - 1.9e-28 96.0 18.3 1.7e-05 24.3 0.0 8.5 9 0 0 9 9 8 6 Tetratricopeptide repeat DnaJ PF00226.26 ETS64297.1 - 1.2e-22 79.4 3.6 2.9e-22 78.1 2.5 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 ETS64297.1 - 4.2e-16 57.9 23.6 8.1e-05 22.9 0.4 8.0 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETS64297.1 - 8.1e-15 54.5 26.1 0.00011 22.0 0.0 6.1 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 ETS64297.1 - 1.2e-14 54.3 32.6 2e-06 28.0 0.8 6.5 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETS64297.1 - 3.3e-14 51.4 2.1 0.073 12.8 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETS64297.1 - 3.8e-12 46.5 33.5 6.2e-06 26.7 0.8 5.9 2 2 5 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETS64297.1 - 9.8e-11 40.6 6.7 0.14 12.0 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS64297.1 - 1.7e-10 40.2 6.6 0.24 11.6 0.0 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETS64297.1 - 3.2e-09 36.5 21.2 0.00035 20.3 1.4 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 ETS64297.1 - 2.5e-08 33.9 12.5 0.00013 22.0 0.1 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETS64297.1 - 1.7e-06 28.1 8.7 1.2 9.6 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 ETS64297.1 - 0.0031 17.7 11.5 0.21 12.1 0.2 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETS64297.1 - 0.013 14.7 1.9 0.077 12.2 0.1 2.7 2 0 0 2 2 2 0 SHNi-TPR BTAD PF03704.12 ETS64297.1 - 0.022 15.0 26.1 0.2 11.9 9.1 5.1 3 2 0 3 3 3 0 Bacterial transcriptional activator domain Coatomer_E PF04733.9 ETS64297.1 - 0.088 11.9 0.1 0.088 11.9 0.1 3.9 3 1 2 5 5 5 0 Coatomer epsilon subunit DUF3856 PF12968.2 ETS64297.1 - 0.13 12.0 15.0 0.024 14.4 4.4 3.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) AP_endonuc_2 PF01261.19 ETS64298.1 - 8e-21 74.3 0.0 7.4e-20 71.1 0.0 2.2 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.6 ETS64298.1 - 7.2e-09 35.5 0.0 1.9e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ETS64298.1 - 9.5e-09 35.4 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 ETS64299.1 - 1.7e-113 379.5 22.7 2.2e-113 379.2 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS64299.1 - 1.4e-28 99.6 27.8 1.4e-28 99.6 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Plus-3 PF03126.13 ETS64299.1 - 3.9e-13 49.3 0.0 7.5e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain DUF899 PF05988.7 ETS64300.1 - 0.12 11.8 0.2 0.31 10.4 0.1 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF899) UCH PF00443.24 ETS64301.1 - 7.5e-68 228.5 0.0 1.2e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS64301.1 - 5e-23 81.9 0.0 8.1e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 ETS64301.1 - 1.1e-06 28.5 0.2 3.5e-06 26.9 0.2 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.15 ETS64301.1 - 0.002 18.4 0.0 0.0068 16.7 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 ETS64301.1 - 0.049 13.1 0.6 0.098 12.1 0.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DivIVA PF05103.8 ETS64301.1 - 4.4 7.3 9.8 7.2 6.6 0.0 2.6 3 0 0 3 3 3 0 DivIVA protein Aldedh PF00171.17 ETS64302.1 - 4.6e-161 536.2 0.0 5.2e-161 536.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS64302.1 - 0.0021 16.8 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS64302.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) PX PF00787.19 ETS64303.1 - 6.8e-13 48.4 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 ETS64303.1 - 8.6e-11 41.3 4.6 1.5e-10 40.6 3.2 1.3 1 0 0 1 1 1 1 SNARE domain NPV_P10 PF05531.7 ETS64303.1 - 0.52 10.6 4.0 1.4 9.2 1.8 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Pneumo_att_G PF05539.6 ETS64303.1 - 1.5 8.0 4.8 2 7.7 3.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Actin PF00022.14 ETS64304.1 - 1.4e-116 389.2 0.0 1.7e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETS64304.1 - 0.017 13.7 0.0 0.061 11.9 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein PCNA_N PF00705.13 ETS64306.1 - 1.5e-48 163.4 2.3 2.2e-48 162.9 1.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 ETS64306.1 - 1.7e-43 147.6 0.6 4.6e-22 78.3 0.1 2.5 2 1 1 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 ETS64306.1 - 8.4e-05 21.8 0.0 0.00016 20.9 0.0 1.6 1 1 0 1 1 1 1 Rad9 DUF4236 PF14020.1 ETS64306.1 - 0.02 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) WD40 PF00400.27 ETS64307.1 - 1e-37 126.6 26.5 7.1e-08 32.0 0.0 9.0 8 1 1 9 9 9 7 WD domain, G-beta repeat PFU PF09070.6 ETS64307.1 - 4.6e-10 39.5 0.0 8.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.1 ETS64307.1 - 0.03 14.1 0.0 19 5.1 0.0 4.0 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region DUF3639 PF12341.3 ETS64307.1 - 0.13 12.2 0.3 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) RCC1_2 PF13540.1 ETS64308.1 - 2.2e-12 46.2 20.6 0.00013 21.4 0.0 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 ETS64308.1 - 2.3e-07 30.9 13.6 2.2 8.5 0.0 6.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.28 ETS64308.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 ETS64308.1 - 0.094 12.4 0.1 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like Elongin_A PF06881.6 ETS64308.1 - 0.1 13.0 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MFS_1 PF07690.11 ETS64311.1 - 7.5e-19 67.6 26.9 2.5e-15 56.0 6.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS64311.1 - 6.1e-18 64.6 23.9 4.3e-12 45.3 8.8 3.2 1 1 1 2 2 2 2 Sugar (and other) transporter Polyketide_cyc PF03364.15 ETS64312.1 - 2.3e-26 92.3 0.1 3.8e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 ETS64312.1 - 7.1e-08 32.7 0.3 1.8e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Epimerase PF01370.16 ETS64312.1 - 4.8e-06 26.1 0.0 3e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS64312.1 - 0.00052 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS64312.1 - 0.00061 19.8 0.1 0.0042 17.1 0.0 2.5 3 0 0 3 3 3 1 NADH(P)-binding NmrA PF05368.8 ETS64312.1 - 0.13 11.4 1.2 2 7.5 0.1 2.7 3 0 0 3 3 3 0 NmrA-like family MFS_1 PF07690.11 ETS64313.1 - 4.3e-35 121.0 31.4 4.3e-35 121.0 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex2_Pex12 PF04757.9 ETS64313.1 - 0.006 16.0 0.5 0.014 14.8 0.3 1.5 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region DUF4448 PF14610.1 ETS64314.1 - 5.7e-16 58.5 0.0 9e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4083 PF13314.1 ETS64314.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Tim17 PF02466.14 ETS64315.1 - 7e-22 77.8 0.1 7e-22 77.8 0.0 3.6 4 0 0 4 4 4 1 Tim17/Tim22/Tim23/Pmp24 family Tim54 PF11711.3 ETS64315.1 - 0.45 9.0 4.1 0.075 11.6 0.1 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 ETS64315.1 - 9 6.0 13.4 2.4 7.9 5.9 2.2 2 0 0 2 2 2 0 DDHD domain Ribosomal_L28e PF01778.12 ETS64316.1 - 5.5e-31 107.3 0.7 5.5e-31 107.3 0.5 2.2 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 ETS64316.1 - 3.4e-21 75.2 21.3 3.4e-21 75.2 14.7 2.8 1 1 2 3 3 3 1 Mak16 protein C-terminal region CENP-T PF15511.1 ETS64316.1 - 0.0041 16.4 15.6 0.0054 16.0 10.8 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T SGT1 PF07093.6 ETS64316.1 - 0.019 13.3 17.2 0.027 12.8 11.9 1.2 1 0 0 1 1 1 0 SGT1 protein PYC_OADA PF02436.13 ETS64316.1 - 0.071 12.5 0.7 0.13 11.6 0.5 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.7 ETS64316.1 - 0.11 10.3 27.6 0.15 9.9 19.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETS64316.1 - 1.2 7.0 16.4 2.4 6.0 11.4 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 ETS64316.1 - 2.3 7.1 31.4 4.1 6.3 21.7 1.4 1 1 0 1 1 1 0 BUD22 G-alpha PF00503.15 ETS64318.1 - 1.3e-91 307.1 0.0 1.6e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS64318.1 - 2.2e-11 43.3 0.0 7.9e-07 28.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 ETS64318.1 - 0.00081 19.5 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS64318.1 - 0.0016 18.0 0.2 0.0039 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS64318.1 - 0.0019 18.5 0.0 0.004 17.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 ETS64318.1 - 0.0048 16.5 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain TraK PF06586.6 ETS64318.1 - 0.0057 15.8 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 TraK protein GTP_EFTU PF00009.22 ETS64318.1 - 0.0059 16.0 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 ETS64318.1 - 0.019 14.4 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 ETS64318.1 - 0.036 13.8 0.2 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 ETS64318.1 - 0.041 13.8 2.2 0.14 12.0 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 ETS64318.1 - 0.087 11.9 0.0 13 4.8 0.0 2.6 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.7 ETS64318.1 - 0.099 12.2 0.2 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 ETS64318.1 - 0.1 13.1 0.0 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 ETS64318.1 - 0.14 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Inhibitor_I48 PF10467.4 ETS64318.1 - 0.16 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Pox_A32 PF04665.7 ETS64318.1 - 0.2 10.9 0.1 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF3317 PF11779.3 ETS64319.1 - 0.0064 15.8 0.1 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) START PF01852.14 ETS64320.1 - 6.4e-17 61.5 0.6 6.7e-08 32.1 0.2 3.5 3 0 0 3 3 3 3 START domain DUF3405 PF11885.3 ETS64321.1 - 1.9e-155 517.8 0.7 2.3e-93 313.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) Vezatin PF12632.2 ETS64322.1 - 1.1e-12 47.5 0.0 8e-06 25.1 0.0 3.6 3 0 0 3 3 3 3 Mysoin-binding motif of peroxisomes Ribosomal_L21p PF00829.16 ETS64323.1 - 1.8e-13 50.4 1.6 3.7e-06 26.9 0.6 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein ATP-synt_ab PF00006.20 ETS64324.1 - 7.2e-70 234.8 0.0 1.1e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETS64324.1 - 2.2e-23 82.8 0.1 6.5e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETS64324.1 - 4e-20 71.8 2.0 1e-19 70.4 1.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 ETS64324.1 - 2.4e-05 24.1 1.1 5.1e-05 23.0 0.8 1.6 1 0 0 1 1 1 1 HAS barrel domain Dynamin_M PF01031.15 ETS64325.1 - 8.1e-114 379.3 0.0 1.1e-113 378.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 ETS64325.1 - 2.2e-54 183.7 0.0 5.3e-54 182.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 ETS64325.1 - 3.8e-29 100.4 1.6 5.2e-29 99.9 0.4 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 ETS64325.1 - 0.0025 17.7 0.1 0.033 14.1 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 ETS64325.1 - 0.0082 16.6 0.3 0.078 13.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 ETS64325.1 - 0.042 12.9 0.1 3.2 6.8 0.0 2.5 2 0 0 2 2 2 0 AIG1 family AATase PF07247.7 ETS64326.1 - 8.3e-11 41.1 0.0 4.4e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 ETS64326.1 - 0.0029 16.5 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 Condensation domain DUF1752 PF08550.5 ETS64329.1 - 6e-12 44.9 2.7 1.2e-11 43.9 1.9 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cellulase PF00150.13 ETS64331.1 - 7.3e-08 31.9 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Herpes_US9 PF06072.6 ETS64331.1 - 0.17 11.7 0.7 0.32 10.8 0.5 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 TPPK_C PF12555.3 ETS64331.1 - 0.48 10.1 5.7 0.082 12.6 1.2 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Zw10 PF06248.8 ETS64332.1 - 4.7e-14 51.4 0.0 2.3e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 ETS64332.1 - 0.024 13.8 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Dor1 PF04124.7 ETS64332.1 - 0.028 12.8 0.5 0.056 11.9 0.3 1.4 1 0 0 1 1 1 0 Dor1-like family Myosin_HC-like PF07058.6 ETS64334.1 - 2.2 7.2 10.7 0.028 13.5 1.4 2.1 2 1 0 2 2 2 0 Myosin II heavy chain-like Ctr PF04145.10 ETS64335.1 - 7e-38 129.9 1.2 4.1e-37 127.4 0.8 2.4 1 0 0 1 1 1 1 Ctr copper transporter family VPS9 PF02204.13 ETS64335.1 - 3e-30 104.3 0.2 6.7e-30 103.1 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 ETS64335.1 - 8.8e-13 47.4 0.3 1.9e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 CUE domain LisH PF08513.6 ETS64337.1 - 0.013 15.2 0.1 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 LisH Cutinase PF01083.17 ETS64337.1 - 0.066 12.9 1.8 0.12 12.0 1.3 1.4 1 0 0 1 1 1 0 Cutinase WD40 PF00400.27 ETS64339.1 - 5.1e-12 45.1 0.8 1.6 8.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat FF PF01846.14 ETS64340.1 - 2e-27 94.8 11.5 8.2e-10 38.4 0.0 5.8 6 0 0 6 6 6 4 FF domain WW PF00397.21 ETS64340.1 - 2.7e-11 43.0 14.2 4.8e-06 26.3 2.3 2.5 2 0 0 2 2 2 2 WW domain Creatininase PF02633.9 ETS64340.1 - 0.005 15.9 1.8 0.0086 15.1 0.6 1.9 2 0 0 2 2 2 1 Creatinine amidohydrolase U3_snoRNA_assoc PF08297.6 ETS64340.1 - 0.91 9.8 0.0 0.91 9.8 0.0 3.9 4 0 0 4 4 4 0 U3 snoRNA associated AAA_16 PF13191.1 ETS64340.1 - 8.5 6.3 12.6 17 5.3 4.9 3.1 1 1 1 2 2 2 0 AAA ATPase domain RRM_1 PF00076.17 ETS64341.1 - 6.1e-30 102.6 0.1 2.1e-15 56.0 0.0 5.2 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64341.1 - 1.3e-17 63.4 0.0 1.1e-05 25.3 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64341.1 - 4.6e-13 48.7 0.0 0.00087 19.1 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_CoA_synt_C PF08540.5 ETS64342.1 - 8.9e-84 281.2 0.1 1.2e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 ETS64342.1 - 2.5e-81 271.3 0.2 9.1e-78 259.7 0.1 2.5 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 ETS64342.1 - 0.0028 17.6 0.0 0.026 14.5 0.0 2.4 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 ETS64342.1 - 0.028 14.0 0.4 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cu-oxidase_3 PF07732.10 ETS64343.1 - 2.9e-34 117.3 0.3 6.9e-34 116.1 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS64343.1 - 4.7e-29 100.6 7.2 2.1e-23 82.3 0.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS64343.1 - 1.7e-15 57.2 0.0 2.3e-11 43.8 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Amidase PF01425.16 ETS64344.1 - 1e-95 321.2 0.0 1.2e-95 320.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 ETS64345.1 - 1.1e-42 145.9 0.0 1.7e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64345.1 - 1.1e-14 54.1 0.0 1.9e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETS64345.1 - 0.00011 21.6 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 ETS64345.1 - 0.028 13.3 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 ETS64345.1 - 0.15 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_11 PF13414.1 ETS64346.1 - 2.1e-27 94.5 0.8 1e-17 63.5 1.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETS64346.1 - 3e-24 83.5 0.2 7.8e-09 34.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS64346.1 - 4.1e-18 63.7 0.1 5.7e-07 28.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETS64346.1 - 3.2e-13 49.9 2.6 2.9e-06 27.8 0.1 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat Abhydrolase_2 PF02230.11 ETS64346.1 - 4.1e-12 45.9 0.0 9.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase TPR_14 PF13428.1 ETS64346.1 - 9e-12 44.5 0.4 3.1e-05 24.2 0.0 4.4 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS64346.1 - 2.6e-11 42.4 0.1 0.00041 19.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS64346.1 - 1.3e-10 40.6 0.0 6.7e-05 22.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS64346.1 - 8.2e-10 37.7 0.0 7.9e-06 25.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS64346.1 - 4.4e-09 36.5 0.2 6.9e-05 23.1 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS64346.1 - 2.1e-07 30.7 0.3 6.8e-06 25.9 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 ETS64346.1 - 3.2e-05 24.2 0.1 0.0046 17.2 0.0 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 ETS64346.1 - 0.00023 21.4 1.5 2.9 8.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS64346.1 - 0.00023 20.9 0.0 0.056 13.3 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS64346.1 - 0.002 18.2 0.1 0.015 15.4 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 ETS64346.1 - 0.0023 17.0 0.7 0.0061 15.6 0.0 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS64346.1 - 0.011 15.6 0.0 0.66 10.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 ETS64346.1 - 0.05 13.8 0.9 10 6.3 0.4 2.5 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation XPC-binding PF09280.6 ETS64346.1 - 0.069 12.6 7.3 0.053 12.9 3.4 2.1 2 0 0 2 2 2 0 XPC-binding domain MIT PF04212.13 ETS64346.1 - 0.21 11.4 5.4 1.4 8.8 0.2 2.8 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain HRDC PF00570.18 ETS64346.1 - 0.24 11.1 0.9 2 8.1 0.1 2.7 2 0 0 2 2 2 0 HRDC domain DHHA1 PF02272.14 ETS64346.1 - 2.5 7.8 9.3 1.3 8.8 0.0 3.2 2 1 1 3 3 3 0 DHHA1 domain ATG16 PF08614.6 ETS64346.1 - 2.9 7.6 4.0 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) RNase_H2_suC PF08615.6 ETS64347.1 - 1.1e-22 80.3 0.0 3.4e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ebola_NP PF05505.7 ETS64347.1 - 0.78 7.7 5.1 1 7.3 3.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 ETS64347.1 - 0.89 7.5 5.8 1.2 7.1 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.15 ETS64348.1 - 2e-68 230.8 0.3 3.7e-68 229.9 0.2 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS64348.1 - 1e-06 27.5 0.2 1.8e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 ETS64348.1 - 0.00072 18.7 0.6 0.0018 17.4 0.1 1.9 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Actin PF00022.14 ETS64348.1 - 0.012 14.0 0.2 0.76 8.1 0.0 2.1 1 1 1 2 2 2 0 Actin PilM_2 PF11104.3 ETS64348.1 - 0.035 12.9 0.0 0.52 9.1 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; DUF4164 PF13747.1 ETS64349.1 - 0.059 13.5 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) MBOAT PF03062.14 ETS64350.1 - 9.4e-35 120.2 4.9 9.4e-35 120.2 3.4 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 ETS64350.1 - 0.00062 19.7 3.9 0.0022 18.0 2.7 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_23 PF13489.1 ETS64351.1 - 2.7e-14 53.2 0.0 3.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS64351.1 - 3.6e-14 53.0 0.0 6.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS64351.1 - 5.7e-14 51.9 0.0 1.1e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS64351.1 - 6.3e-14 52.5 0.0 1.1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS64351.1 - 8.8e-14 51.7 0.1 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS64351.1 - 1.2e-06 28.0 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETS64351.1 - 1.5e-06 28.2 0.0 3e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETS64351.1 - 3.7e-06 26.4 0.0 5.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 ETS64351.1 - 2.3e-05 23.6 0.0 0.00011 21.4 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 ETS64351.1 - 2.9e-05 23.2 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 ETS64351.1 - 0.00017 20.8 0.1 0.00032 19.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 ETS64351.1 - 0.00018 21.7 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 ETS64351.1 - 0.0035 16.0 0.0 0.0058 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FmrO PF07091.6 ETS64351.1 - 0.0046 15.9 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) NodS PF05401.6 ETS64351.1 - 0.0068 15.8 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 ETS64351.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 ETS64351.1 - 0.014 14.4 0.0 0.051 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase TehB PF03848.9 ETS64351.1 - 0.022 13.8 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.7 ETS64351.1 - 0.069 12.0 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase PPR_2 PF13041.1 ETS64352.1 - 0.076 13.0 0.0 6.7 6.7 0.0 3.9 5 0 0 5 5 5 0 PPR repeat family PPR_1 PF12854.2 ETS64352.1 - 0.084 12.3 0.0 11 5.6 0.0 3.1 3 0 0 3 3 3 0 PPR repeat Thioredoxin PF00085.15 ETS64353.1 - 3e-26 91.0 0.2 1.2e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS64353.1 - 3.3e-07 30.4 0.4 3.3e-07 30.4 0.3 3.4 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS64353.1 - 0.00012 22.0 0.1 0.002 18.1 0.0 2.9 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 ETS64353.1 - 0.00015 21.7 0.3 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 ETS64353.1 - 0.022 14.3 0.1 0.022 14.3 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin FAM60A PF15396.1 ETS64353.1 - 1 9.0 14.9 0.087 12.5 6.4 2.0 1 1 0 2 2 2 0 Protein Family FAM60A Allexi_40kDa PF05549.6 ETS64353.1 - 9 5.4 9.0 1 8.5 2.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein WWbp PF10349.4 ETS64354.1 - 3.2 8.6 7.5 6.4 7.6 5.2 1.6 1 1 0 1 1 1 0 WW-domain ligand protein Lactamase_B_2 PF12706.2 ETS64355.1 - 3.9e-35 121.1 0.1 5.5e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS64355.1 - 2.9e-14 53.1 0.0 5.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS64355.1 - 0.00051 19.7 0.0 0.0037 16.9 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Prenyltrans PF00432.16 ETS64356.1 - 5.1e-32 109.1 6.2 7e-07 28.7 0.0 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETS64356.1 - 2.3e-17 63.4 0.3 1.5e-14 54.3 0.0 3.4 3 0 0 3 3 3 2 Prenyltransferase-like Amidohydro_4 PF13147.1 ETS64357.1 - 2.4e-29 103.2 3.4 2.4e-29 103.2 2.4 2.8 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS64357.1 - 6.6e-18 64.2 0.8 5.1e-13 48.6 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 ETS64357.1 - 1.6e-06 28.0 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family UNC-93 PF05978.11 ETS64358.1 - 1.3e-11 44.2 10.5 3e-11 43.0 6.0 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 ETS64358.1 - 1.5e-10 40.3 35.0 1.5e-10 40.3 24.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-CCCH PF00642.19 ETS64359.1 - 7.6e-13 47.8 24.0 5.8e-06 25.8 1.7 4.6 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETS64359.1 - 5.7 7.1 10.9 11 6.2 0.6 3.3 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2235 PF09994.4 ETS64360.1 - 1.1e-57 195.5 0.0 1.3e-56 191.9 0.0 2.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1469 PF07332.6 ETS64362.1 - 0.0037 16.9 1.1 0.0037 16.9 0.7 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1469) Antirestrict PF03230.8 ETS64362.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 Antirestriction protein His_Phos_1 PF00300.17 ETS64363.1 - 2.5e-40 138.1 0.0 2.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sortase PF04203.8 ETS64363.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Sortase family Ank_4 PF13637.1 ETS64364.1 - 3.1e-10 40.2 2.0 0.0004 20.8 0.4 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS64364.1 - 2.1e-09 37.5 2.0 0.00066 19.9 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS64364.1 - 9.7e-08 31.4 3.5 0.0077 15.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETS64364.1 - 3.1e-06 26.8 2.5 0.026 14.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 ETS64364.1 - 1.2e-05 24.8 0.3 0.0001 21.9 0.2 2.1 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.1 ETS64364.1 - 1.5e-05 25.0 4.0 0.014 15.6 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Fib_alpha PF08702.5 ETS64364.1 - 0.18 11.9 2.3 15 5.7 0.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rtf2 PF04641.7 ETS64366.1 - 2.2e-71 240.0 1.9 2.5e-71 239.9 1.3 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 ETS64366.1 - 0.0013 18.1 0.6 0.032 13.7 0.0 2.7 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit CDC45 PF02724.9 ETS64366.1 - 4.3 5.2 8.9 5.7 4.8 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TAF4 PF05236.9 ETS64366.1 - 8.9 5.5 15.5 14 4.8 10.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SHS2_Rpb7-N PF03876.12 ETS64367.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 ETS64367.1 - 2.3e-09 37.1 0.3 7.5e-09 35.5 0.2 1.8 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 ETS64367.1 - 0.034 14.3 0.1 0.066 13.4 0.1 1.6 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Ribonuc_P_40 PF08584.6 ETS64368.1 - 1.1e-22 80.3 0.0 7.7e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit DUF1455 PF07306.6 ETS64368.1 - 0.037 14.1 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) zf-RING_2 PF13639.1 ETS64369.1 - 1.1e-11 44.3 1.6 2.1e-11 43.4 1.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS64369.1 - 1.5e-08 34.5 1.3 2.6e-08 33.7 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS64369.1 - 5.4e-07 29.1 0.6 9.9e-07 28.3 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS64369.1 - 7.2e-07 28.8 0.7 1.2e-06 28.0 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETS64369.1 - 3.3e-06 27.1 0.7 6.9e-06 26.0 0.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETS64369.1 - 5.3e-05 22.7 0.4 9.3e-05 22.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 ETS64369.1 - 0.00056 19.8 0.7 0.0012 18.7 0.5 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 ETS64369.1 - 0.0037 16.9 0.1 0.0088 15.7 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETS64369.1 - 0.12 12.2 0.2 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tropomyosin_1 PF12718.2 ETS64369.1 - 0.2 11.5 29.7 6 6.7 17.1 2.5 1 1 1 2 2 2 0 Tropomyosin like RINGv PF12906.2 ETS64369.1 - 0.2 11.7 0.6 0.52 10.3 0.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 ETS64369.1 - 0.23 11.3 1.1 0.71 9.7 0.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Fib_alpha PF08702.5 ETS64369.1 - 2.1 8.4 17.4 0.88 9.6 9.7 2.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SYS1 PF09801.4 ETS64370.1 - 1.3e-24 86.8 4.7 6.3e-18 65.1 1.7 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network TPPK_C PF12555.3 ETS64370.1 - 3.3 7.5 6.8 4.3 7.1 0.2 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal FMO-like PF00743.14 ETS64371.1 - 1.1e-34 119.5 0.0 6.1e-12 44.5 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS64371.1 - 2.6e-18 66.8 0.0 9e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS64371.1 - 3.3e-06 27.0 0.0 9.6e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS64371.1 - 1.2e-05 25.1 0.0 8.2e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 ETS64371.1 - 0.00013 20.9 0.0 0.13 11.1 0.0 3.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS64371.1 - 0.00036 20.4 0.0 2.1 8.1 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS64371.1 - 0.00068 19.9 0.4 0.39 11.1 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS64371.1 - 0.0009 19.3 0.3 0.012 15.7 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 ETS64371.1 - 0.02 13.9 0.0 4.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 ETS64371.1 - 0.095 12.9 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 ETS64372.1 - 5e-10 39.2 0.0 1.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS64372.1 - 0.00097 19.2 0.0 0.076 13.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS64372.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 ETS64372.1 - 0.0016 18.3 0.0 0.59 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS64372.1 - 0.0021 16.6 0.1 0.0083 14.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 ETS64372.1 - 0.0048 15.8 0.2 0.014 14.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS64372.1 - 0.07 12.7 0.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 ETS64372.1 - 0.086 12.6 1.1 0.24 11.1 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS64372.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Sec7 PF01369.15 ETS64373.1 - 3.6e-36 124.6 0.0 5.9e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_10 PF15411.1 ETS64373.1 - 0.13 12.4 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4449 PF14613.1 ETS64374.1 - 5.1e-33 114.3 0.4 5.1e-33 114.3 0.2 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) TPR_6 PF13174.1 ETS64374.1 - 1 9.9 4.6 23 5.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BNR PF02012.15 ETS64375.1 - 1.1e-07 30.5 44.9 0.72 9.9 0.0 11.9 11 0 0 11 11 11 5 BNR/Asp-box repeat Fe_dep_repr_C PF02742.10 ETS64375.1 - 0.0012 18.5 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain F5_F8_type_C PF00754.20 ETS64375.1 - 0.0045 16.8 0.9 0.59 9.9 0.0 4.5 5 0 0 5 5 5 1 F5/8 type C domain PSII_BNR PF14870.1 ETS64375.1 - 0.02 13.8 2.5 7.8 5.3 0.0 4.0 4 1 1 5 5 5 0 Photosynthesis system II assembly factor YCF48 SRF-TF PF00319.13 ETS64376.1 - 3.9e-22 77.2 0.0 6.1e-22 76.5 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MS_channel PF00924.13 ETS64377.1 - 9.7e-22 77.3 1.4 1.7e-21 76.5 1.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 ETS64377.1 - 3.1e-06 26.0 0.1 6.4e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETS64377.1 - 4.5e-05 22.9 0.0 0.00015 21.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 ETS64377.1 - 0.0003 19.9 0.2 0.00067 18.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETS64377.1 - 0.00035 20.6 0.1 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 ETS64377.1 - 0.0016 18.0 0.1 0.003 17.1 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair Tubulin PF00091.20 ETS64378.1 - 5.6e-65 219.1 0.0 8.8e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS64378.1 - 1.6e-41 141.2 0.0 2.9e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETS64378.1 - 0.00057 19.9 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETS64378.1 - 0.0033 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MFS_1 PF07690.11 ETS64381.1 - 1.1e-35 123.0 62.0 1.2e-35 122.8 39.0 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS64381.1 - 4.5e-06 25.5 15.4 4.5e-06 25.5 10.7 3.2 2 2 1 3 3 3 2 Sugar (and other) transporter Cellulose_synt PF03552.9 ETS64381.1 - 0.42 8.8 5.1 0.84 7.8 3.5 1.4 1 0 0 1 1 1 0 Cellulose synthase UPF0150 PF03681.10 ETS64387.1 - 0.082 12.5 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) Nab2 PF11517.3 ETS64387.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) STT3 PF02516.9 ETS64389.1 - 1.5e-130 436.3 34.7 8.9e-125 417.3 22.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pep3_Vps18 PF05131.9 ETS64390.1 - 1.1e-41 141.6 0.0 2.6e-41 140.4 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 ETS64390.1 - 7e-12 45.1 2.9 1.6e-06 27.7 0.0 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 ETS64390.1 - 0.00054 20.1 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 ETS64390.1 - 0.0071 16.1 5.4 0.01 15.6 2.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS64390.1 - 0.05 13.6 3.7 0.046 13.7 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 ETS64390.1 - 0.12 12.4 0.0 0.46 10.5 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3778 PF12620.3 ETS64390.1 - 0.13 11.8 0.0 0.47 10.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) zf-RING_5 PF14634.1 ETS64390.1 - 0.27 10.9 7.3 0.019 14.6 1.4 1.8 2 0 0 2 2 2 0 zinc-RING finger domain MTP18 PF10558.4 ETS64391.1 - 1.8e-61 206.4 0.5 2.6e-61 205.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Glyco_hydro_18 PF00704.23 ETS64392.1 - 0.0084 15.5 0.5 0.27 10.6 0.4 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4006 PF13179.1 ETS64392.1 - 0.038 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) ARL6IP6 PF15062.1 ETS64392.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Pkinase PF00069.20 ETS64393.1 - 7.2e-71 238.3 0.0 9.1e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64393.1 - 4.2e-31 107.9 0.0 7.9e-31 107.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS64393.1 - 3.3e-05 23.0 0.0 5.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS64393.1 - 0.0039 16.9 0.0 0.023 14.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS64393.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_S9_N PF02897.10 ETS64394.1 - 1.3e-85 287.5 2.7 1.7e-85 287.0 1.8 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 ETS64394.1 - 1.8e-52 177.6 0.1 2.7e-52 177.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2974 PF11187.3 ETS64394.1 - 0.15 11.4 0.1 0.49 9.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SAD_SRA PF02182.12 ETS64395.1 - 1.4e-47 160.9 0.2 2.7e-47 159.9 0.0 1.6 2 0 0 2 2 2 1 SAD/SRA domain MSP1_C PF07462.6 ETS64395.1 - 0.091 11.1 0.5 0.15 10.4 0.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Trypan_PARP PF05887.6 ETS64395.1 - 0.2 11.4 16.1 0.035 13.9 4.8 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Vps5 PF09325.5 ETS64396.1 - 1e-65 221.3 6.3 1e-65 221.3 4.4 2.6 2 1 0 2 2 2 1 Vps5 C terminal like RmlD_sub_bind PF04321.12 ETS64396.1 - 2.5e-51 174.2 0.0 4.8e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 ETS64396.1 - 4.5e-25 88.4 0.0 9.6e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 ETS64396.1 - 4.9e-23 81.0 0.0 9.7e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 PX domain Polysacc_synt_2 PF02719.10 ETS64396.1 - 2.1e-07 30.1 0.2 4.2e-06 25.8 0.1 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS64396.1 - 0.0001 21.3 0.0 0.0001 21.3 0.0 2.8 2 1 0 3 3 3 1 Male sterility protein MIP-T3 PF10243.4 ETS64396.1 - 0.0016 17.0 26.7 0.0016 17.0 18.5 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 SPX PF03105.14 ETS64396.1 - 10 5.8 18.8 9.4 5.9 9.8 2.4 2 0 0 2 2 2 0 SPX domain HAD_2 PF13419.1 ETS64397.1 - 6.8e-16 58.9 0.0 9.7e-11 42.2 0.0 2.5 1 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS64397.1 - 2e-08 34.9 0.0 7.7e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS64397.1 - 0.0044 16.6 0.1 0.026 14.2 0.0 2.2 3 1 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.2 ETS64397.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETS64397.1 - 0.12 12.2 0.0 19 5.2 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Metallophos PF00149.23 ETS64398.1 - 2e-30 105.6 0.0 2.7e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPR_11 PF13414.1 ETS64398.1 - 3.9e-21 74.4 3.3 5.4e-16 57.9 0.5 2.5 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 ETS64398.1 - 2.3e-12 46.7 0.0 5.1e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 ETS64398.1 - 3.1e-11 42.3 2.0 0.0002 20.8 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS64398.1 - 7.1e-09 34.9 1.9 0.021 14.6 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS64398.1 - 0.00011 22.7 1.6 0.00018 22.0 0.4 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS64398.1 - 0.0034 17.4 0.9 2.9 8.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS64398.1 - 0.035 13.9 0.3 0.24 11.2 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS64398.1 - 0.11 12.3 0.1 35 4.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat VitD-bind_III PF09164.5 ETS64398.1 - 0.11 12.0 0.2 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III TPR_12 PF13424.1 ETS64398.1 - 0.24 11.3 1.0 0.57 10.1 0.7 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HMG_box_5 PF14887.1 ETS64399.1 - 0.0092 15.7 0.4 0.028 14.2 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box 5 BAR PF03114.13 ETS64400.1 - 4.1e-48 163.9 1.0 4.9e-48 163.6 0.7 1.1 1 0 0 1 1 1 1 BAR domain AAA_13 PF13166.1 ETS64400.1 - 0.0013 17.2 1.6 0.0017 16.9 1.1 1.1 1 0 0 1 1 1 1 AAA domain Arfaptin PF06456.8 ETS64400.1 - 0.0038 16.6 2.8 0.008 15.5 2.0 1.8 1 1 0 1 1 1 1 Arfaptin-like domain Laminin_I PF06008.9 ETS64400.1 - 0.019 14.3 0.8 0.019 14.3 0.6 2.2 3 0 0 3 3 3 0 Laminin Domain I HHH_8 PF14716.1 ETS64400.1 - 0.046 13.8 2.9 6.8 6.9 0.1 2.7 1 1 1 2 2 2 0 Helix-hairpin-helix domain TMPIT PF07851.8 ETS64400.1 - 0.052 12.6 1.1 0.13 11.3 0.1 1.8 1 1 1 2 2 2 0 TMPIT-like protein RNase_H PF00075.19 ETS64400.1 - 0.067 13.5 0.1 0.095 13.0 0.1 1.2 1 0 0 1 1 1 0 RNase H Myosin_tail_1 PF01576.14 ETS64400.1 - 0.079 10.6 4.5 0.12 10.0 3.1 1.3 1 1 0 1 1 1 0 Myosin tail DUF746 PF05344.6 ETS64400.1 - 0.097 12.2 0.0 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Laminin_II PF06009.7 ETS64400.1 - 0.21 11.3 1.9 2.1 8.1 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II Vps5 PF09325.5 ETS64400.1 - 0.28 10.4 4.3 1.6 7.9 3.0 2.0 1 1 0 1 1 1 0 Vps5 C terminal like Sec2p PF06428.6 ETS64400.1 - 0.32 10.8 5.0 1.9 8.3 0.5 3.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p GAS PF13851.1 ETS64400.1 - 0.33 10.1 5.0 0.32 10.1 0.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Sigma70_ner PF04546.8 ETS64400.1 - 0.43 10.1 4.6 0.84 9.2 1.6 2.5 1 1 2 3 3 3 0 Sigma-70, non-essential region APG6 PF04111.7 ETS64400.1 - 0.59 9.1 3.7 0.14 11.1 0.3 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 ETS64400.1 - 2.2 8.3 7.0 1.9 8.5 1.0 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.8 ETS64400.1 - 2.5 8.8 5.1 1.8 9.3 0.2 2.8 3 1 0 3 3 3 0 Occludin homology domain DivIC PF04977.10 ETS64400.1 - 3.1 7.3 6.8 0.24 10.9 0.5 2.3 3 0 0 3 3 3 0 Septum formation initiator Snf7 PF03357.16 ETS64401.1 - 6.2e-49 165.6 14.1 7.4e-49 165.4 9.8 1.1 1 0 0 1 1 1 1 Snf7 NuA4 PF09340.5 ETS64401.1 - 0.0022 17.5 0.8 0.0044 16.6 0.5 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Prefoldin_2 PF01920.15 ETS64401.1 - 0.016 14.9 9.4 1.7 8.4 0.0 3.3 2 1 0 2 2 2 0 Prefoldin subunit Mod_r PF07200.8 ETS64401.1 - 0.048 13.5 9.1 0.027 14.3 4.8 1.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Soyouz_module PF14313.1 ETS64401.1 - 0.055 13.0 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Mnd1 PF03962.10 ETS64401.1 - 0.26 10.9 12.3 2 8.0 8.6 2.1 1 1 0 1 1 1 0 Mnd1 family Prefoldin PF02996.12 ETS64401.1 - 0.32 10.6 9.8 10 5.8 0.8 3.4 4 0 0 4 4 4 0 Prefoldin subunit PEP-utilisers_N PF05524.8 ETS64401.1 - 0.39 10.5 9.5 0.68 9.7 2.4 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal V_ATPase_I PF01496.14 ETS64401.1 - 0.5 8.1 2.8 0.69 7.7 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1569 PF07606.6 ETS64401.1 - 0.56 10.1 2.8 9.4 6.1 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1569) DUF848 PF05852.6 ETS64401.1 - 0.58 9.9 9.1 0.64 9.8 5.2 1.9 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Hemerythrin PF01814.18 ETS64401.1 - 0.65 10.1 5.9 0.76 9.9 2.3 2.4 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Macoilin PF09726.4 ETS64401.1 - 0.71 8.0 5.9 0.88 7.7 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein FlxA PF14282.1 ETS64401.1 - 1.2 9.1 9.5 1.2 9.1 3.8 2.3 1 1 1 2 2 2 0 FlxA-like protein NPV_P10 PF05531.7 ETS64401.1 - 1.9 8.7 7.1 3 8.1 0.1 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein FoP_duplication PF13865.1 ETS64401.1 - 2.2 8.7 6.9 1.8 9.0 0.1 2.8 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Atg14 PF10186.4 ETS64401.1 - 2.8 6.8 8.1 4.2 6.2 5.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ssl1 PF04056.9 ETS64402.1 - 7e-68 228.0 0.0 1.1e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 ETS64402.1 - 1.7e-11 44.5 0.0 3.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.10 ETS64402.1 - 0.11 11.9 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.23 ETS64402.1 - 0.13 11.9 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain DZR PF12773.2 ETS64402.1 - 2 8.2 7.6 1.4 8.7 3.0 2.1 2 0 0 2 2 2 0 Double zinc ribbon Tfb4 PF03850.9 ETS64402.1 - 2.8 7.1 5.5 48 3.0 3.6 2.6 2 1 0 3 3 3 0 Transcription factor Tfb4 DUF1610 PF07754.6 ETS64402.1 - 3.7 7.7 9.6 1.4 9.1 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Tnp_zf-ribbon_2 PF13842.1 ETS64402.1 - 9.5 6.7 8.8 1.5 9.2 3.0 2.0 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Collagen PF01391.13 ETS64403.1 - 1e-06 28.1 24.4 1e-06 28.1 16.9 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Nop53 PF07767.6 ETS64404.1 - 2e-84 283.8 20.6 2.5e-84 283.5 14.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ank_4 PF13637.1 ETS64405.1 - 4.2e-17 62.1 4.5 8.8e-13 48.3 0.8 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS64405.1 - 1.7e-16 59.0 1.8 2.2e-07 30.3 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 ETS64405.1 - 2.1e-16 60.0 1.8 2e-13 50.4 1.4 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS64405.1 - 2.6e-15 54.9 1.5 6.3e-06 25.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS64405.1 - 8.6e-13 48.0 4.0 2.1e-06 27.8 0.3 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Mt_ATP-synt_B PF05405.9 ETS64406.1 - 6.3e-45 152.5 9.3 7.5e-45 152.3 6.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2704 PF10866.3 ETS64406.1 - 0.01 15.2 0.2 0.032 13.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2704) Virulence_fact PF13769.1 ETS64406.1 - 0.089 12.6 1.7 0.22 11.4 1.2 1.7 1 1 0 1 1 1 0 Virulence factor Cauli_DNA-bind PF03310.8 ETS64406.1 - 0.11 12.3 3.6 0.11 12.3 1.3 1.8 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein BCDHK_Adom3 PF10436.4 ETS64408.1 - 1.9e-67 225.8 0.0 3.3e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 ETS64408.1 - 5.2e-19 68.0 0.0 9.9e-19 67.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETS64408.1 - 1.3e-06 28.1 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IFT57 PF10498.4 ETS64408.1 - 0.25 10.0 0.1 0.42 9.3 0.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HSF_DNA-bind PF00447.12 ETS64409.1 - 2.7e-34 117.4 0.8 4.2e-34 116.8 0.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding TPR_MLP1_2 PF07926.7 ETS64409.1 - 0.094 12.4 0.3 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LBP_BPI_CETP PF01273.20 ETS64409.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain DivIC PF04977.10 ETS64409.1 - 0.25 10.8 0.2 0.52 9.8 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DPPIV_N PF00930.16 ETS64410.1 - 2.5e-74 249.9 0.0 5.7e-74 248.8 0.0 1.6 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 ETS64410.1 - 6.9e-46 156.1 3.2 1.1e-45 155.4 2.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS64410.1 - 4.5e-09 36.2 0.8 1.1e-08 34.8 0.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS64410.1 - 1.6e-07 31.4 1.6 1.6e-07 31.4 1.1 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS64410.1 - 2e-06 27.4 4.2 6.2e-06 25.8 2.4 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 ETS64410.1 - 9.5e-06 24.3 0.0 0.00092 17.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 ETS64410.1 - 0.013 14.7 0.5 0.013 14.7 0.4 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase BAAT_C PF08840.6 ETS64410.1 - 0.049 13.3 0.0 5.4 6.6 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.11 ETS64411.1 - 1.3e-22 80.0 35.0 2.7e-17 62.5 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.1 ETS64411.1 - 0.021 14.8 1.0 0.021 14.8 0.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) E1-E2_ATPase PF00122.15 ETS64412.1 - 8.2e-28 96.9 0.1 1.3e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 ETS64412.1 - 7.4e-27 93.5 0.0 1.8e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 ETS64412.1 - 7.1e-25 88.3 0.0 1.3e-24 87.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS64412.1 - 1.3e-22 81.3 0.0 1.9e-21 77.5 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS64412.1 - 4.2e-05 23.4 0.0 9.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 ETS64412.1 - 4.6e-05 22.8 0.0 8.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS64412.1 - 0.026 14.0 0.0 0.37 10.3 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.16 ETS64412.1 - 0.12 11.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 AA_permease PF00324.16 ETS64413.1 - 5.1e-96 321.8 44.2 5.8e-96 321.7 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS64413.1 - 1.5e-26 92.9 49.0 1.8e-26 92.6 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease RA PF00788.18 ETS64414.1 - 2.4e-18 66.3 0.1 4.2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 ETS64414.1 - 2.4e-13 49.2 0.3 3.7e-08 32.6 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SAM_1 PF00536.25 ETS64414.1 - 8e-13 48.3 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 ETS64414.1 - 1e-12 47.7 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 ETS64414.1 - 8.8e-11 41.2 2.7 1.5e-05 24.4 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 ETS64414.1 - 1.1e-08 34.4 1.5 3.5e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain DUF2205 PF10224.4 ETS64415.1 - 0.023 14.2 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) TF_Zn_Ribbon PF08271.7 ETS64416.1 - 8.7e-05 21.7 1.1 0.00017 20.8 0.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 ETS64416.1 - 0.00095 18.2 0.5 0.0016 17.5 0.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 ETS64416.1 - 0.039 13.7 1.3 0.075 12.8 0.9 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.2 ETS64416.1 - 0.082 12.7 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 ETS64416.1 - 0.34 10.9 1.2 0.85 9.6 0.8 1.7 1 0 0 1 1 1 0 Zinc ribbon domain GEMIN8 PF15348.1 ETS64416.1 - 0.62 10.0 11.9 0.87 9.5 0.5 3.3 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 Baculo_PP31 PF05311.6 ETS64416.1 - 2.7 7.1 7.9 0.49 9.6 3.0 1.6 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) ADH_N PF08240.7 ETS64417.1 - 2.8e-27 94.6 0.8 4.2e-27 94.0 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS64417.1 - 2e-09 37.1 0.1 7.5e-05 22.2 0.0 2.7 2 1 1 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 ETS64417.1 - 7.7e-08 31.8 0.0 7.7e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 ETS64417.1 - 1.7e-05 25.6 0.1 6.6e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 ETS64417.1 - 0.00051 20.0 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 ETS64417.1 - 0.0013 17.9 0.0 0.003 16.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 ETS64417.1 - 0.0035 16.8 0.0 0.029 13.8 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 ETS64417.1 - 0.0037 17.0 0.4 0.15 11.8 0.2 2.3 1 1 1 2 2 2 1 ThiF family Shikimate_DH PF01488.15 ETS64417.1 - 0.021 14.9 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 ETS64417.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_31 PF13847.1 ETS64417.1 - 0.089 12.3 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF4451 PF14616.1 ETS64417.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Cation_ATPase_C PF00689.16 ETS64419.1 - 0.0045 16.5 3.7 0.0077 15.7 2.6 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus PIG-P PF08510.7 ETS64419.1 - 0.037 13.6 1.9 0.059 13.0 1.3 1.3 1 0 0 1 1 1 0 PIG-P DUF4234 PF14018.1 ETS64419.1 - 3 7.6 6.2 1.9 8.2 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) HemY_N PF07219.8 ETS64419.1 - 4.5 6.8 6.1 2 8.0 0.9 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Sugar_tr PF00083.19 ETS64420.1 - 4e-17 61.9 27.5 1.6e-15 56.6 19.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.19 ETS64422.1 - 9.1e-54 182.7 1.5 1e-53 182.5 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS64422.1 - 6.2e-06 26.5 0.9 0.0039 17.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS64422.1 - 2.4e-05 24.2 4.5 0.0044 16.9 3.2 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS64422.1 - 0.00012 21.2 1.5 0.0002 20.5 1.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 ETS64422.1 - 0.00022 19.5 0.1 0.076 11.1 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 ETS64422.1 - 0.00041 19.3 7.0 0.0012 17.7 4.8 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 ETS64422.1 - 0.0012 18.6 1.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS64422.1 - 0.0013 18.7 1.6 0.0024 17.8 0.5 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 ETS64422.1 - 0.0017 17.5 0.4 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.14 ETS64422.1 - 0.0051 15.9 0.8 0.22 10.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 ETS64422.1 - 0.0061 15.5 0.3 2.5 6.9 0.1 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 ETS64422.1 - 0.0085 14.7 0.8 0.27 9.8 0.5 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 ETS64422.1 - 0.12 11.2 3.5 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 ETS64422.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 ETS64422.1 - 0.28 10.6 2.5 0.22 10.9 0.6 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Histone PF00125.19 ETS64423.1 - 1.1e-27 95.9 0.0 2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETS64423.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S ADIP PF11559.3 ETS64424.1 - 2.9e-24 85.6 6.5 2.9e-24 85.6 4.5 4.5 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.6 ETS64424.1 - 0.12 12.1 6.0 2.4 7.9 0.1 3.4 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Dabb PF07876.7 ETS64425.1 - 3.5e-19 69.0 0.2 3.9e-19 68.8 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain NAD_binding_10 PF13460.1 ETS64426.1 - 2.2e-10 40.8 0.0 5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding ABC2_membrane PF01061.19 ETS64427.1 - 3.4e-68 228.9 54.4 2.3e-39 134.7 12.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 ETS64427.1 - 2.9e-37 128.0 0.1 2.2e-18 66.8 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 ETS64427.1 - 1.9e-22 78.8 2.4 2.9e-20 71.8 0.0 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_25 PF13481.1 ETS64427.1 - 4.8e-07 29.3 0.3 0.00024 20.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain ABC_trans_N PF14510.1 ETS64427.1 - 7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 ETS64427.1 - 2.7e-05 23.6 2.8 0.012 15.0 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 ETS64427.1 - 6.4e-05 23.0 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 ETS64427.1 - 0.00041 20.6 0.7 0.12 12.6 0.2 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETS64427.1 - 0.0005 19.2 0.3 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS64427.1 - 0.0012 19.6 0.1 0.15 12.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 ETS64427.1 - 0.0033 17.5 2.8 1 9.5 0.2 3.5 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 ETS64427.1 - 0.0058 16.5 0.5 3.2 7.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 ETS64427.1 - 0.0063 15.7 0.0 2 7.5 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 ETS64427.1 - 0.025 14.2 1.5 0.26 10.9 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETS64427.1 - 0.03 14.2 0.2 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS64427.1 - 0.033 13.6 2.2 2.4 7.5 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.14 ETS64427.1 - 0.064 12.7 2.5 0.37 10.1 0.5 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 ETS64427.1 - 0.083 13.2 0.9 0.24 11.7 0.1 2.1 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 ETS64427.1 - 0.085 12.8 9.6 2.7 7.9 3.3 3.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 ETS64427.1 - 0.11 12.2 2.4 11 5.8 0.2 3.1 2 0 0 2 2 2 0 Part of AAA domain ABC_ATPase PF09818.4 ETS64427.1 - 0.15 10.5 0.3 0.38 9.2 0.2 1.6 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 ETS64427.1 - 0.29 10.6 0.3 0.81 9.1 0.2 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 ETS64427.1 - 0.48 9.5 2.9 1.3 8.0 0.3 2.5 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.1 ETS64427.1 - 0.53 9.8 5.8 3.6 7.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 ETS64427.1 - 0.8 9.6 8.9 0.045 13.7 0.9 2.7 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 ETS64427.1 - 1.5 7.7 0.0 3.1 6.7 0.0 1.4 2 0 0 2 2 1 0 AAA ATPase domain Fungal_trans PF04082.13 ETS64428.1 - 1.1e-19 70.4 0.0 2.1e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS64429.1 - 2.1e-26 92.8 1.4 2.6e-26 92.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS64429.1 - 4e-26 92.2 0.3 5e-26 91.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS64429.1 - 9.9e-12 44.8 0.5 1.4e-11 44.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 ETS64429.1 - 0.0055 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 ETS64429.1 - 0.026 13.9 1.1 0.056 12.8 0.8 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_S31 PF05578.7 ETS64429.1 - 0.04 13.1 0.1 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 S4 PF01479.20 ETS64429.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 S4 domain DUF1670 PF07900.6 ETS64429.1 - 0.089 11.9 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1670) ox_reductase_C PF08635.5 ETS64430.1 - 2.8e-50 169.4 0.0 5.2e-50 168.5 0.0 1.4 2 0 0 2 2 2 1 Putative oxidoreductase C terminal GFO_IDH_MocA_C PF02894.12 ETS64430.1 - 2e-06 27.5 0.0 3.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Carla_C4 PF01623.12 ETS64431.1 - 0.47 10.2 4.8 12 5.7 1.3 2.1 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein Calici_coat_C PF08435.6 ETS64433.1 - 0.029 13.6 0.2 0.044 13.0 0.1 1.4 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal DUF4243 PF14027.1 ETS64434.1 - 1.3e-62 212.1 3.8 1.8e-62 211.7 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) p450 PF00067.17 ETS64436.1 - 4.9e-34 117.6 0.0 3.2e-32 111.6 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 ETS64437.1 - 3.7e-44 150.8 31.9 3.7e-44 150.8 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS64437.1 - 3.7e-06 25.4 2.0 6.2e-06 24.6 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 ETS64437.1 - 0.017 15.4 0.5 2.3 8.6 0.1 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) OATP PF03137.15 ETS64437.1 - 0.089 10.8 5.5 0.085 10.9 1.1 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3694 PF12473.3 ETS64437.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Kinesin protein TraW_N PF12477.3 ETS64437.1 - 0.17 11.8 4.6 2.4 8.1 0.0 4.0 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal Myb_DNA-bind_6 PF13921.1 ETS64438.1 - 2.3e-26 91.6 5.7 5.8e-14 51.9 0.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS64438.1 - 3.5e-24 84.5 8.6 9.1e-12 44.8 0.1 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain TRH PF05438.7 ETS64438.1 - 0.00013 21.4 0.1 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Thyrotropin-releasing hormone (TRH) Myb_DNA-bind_5 PF13873.1 ETS64438.1 - 0.00046 20.0 5.0 0.0012 18.7 0.2 3.3 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 ETS64438.1 - 0.0042 17.1 9.9 0.013 15.5 0.8 3.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 ETS64438.1 - 0.026 14.7 4.9 1.3 9.2 0.0 3.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FRG PF08867.6 ETS64438.1 - 0.049 14.1 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 FRG domain Rap1_C PF11626.3 ETS64438.1 - 0.097 12.5 2.5 0.54 10.1 0.3 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAD_binding_3 PF01494.14 ETS64439.1 - 3.9e-15 55.7 3.8 1.2e-13 50.8 2.6 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS64439.1 - 1.1e-11 44.2 3.0 2.1e-06 26.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS64439.1 - 5e-06 25.6 1.2 0.0097 14.7 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 ETS64439.1 - 0.00011 22.3 1.6 0.0049 16.9 1.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS64439.1 - 0.00011 22.0 0.1 0.00035 20.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS64439.1 - 0.00026 21.3 0.2 0.011 16.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS64439.1 - 0.00041 18.9 0.3 0.27 9.6 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.19 ETS64439.1 - 0.00053 19.1 0.1 0.017 14.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 ETS64439.1 - 0.001 18.9 0.1 0.34 10.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS64439.1 - 0.0011 17.7 1.9 0.29 9.7 0.2 2.8 3 0 0 3 3 3 2 Tryptophan halogenase SE PF08491.5 ETS64439.1 - 0.0014 17.5 0.0 0.9 8.3 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Lycopene_cycl PF05834.7 ETS64439.1 - 0.017 14.0 4.6 1.3 7.8 0.3 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 ETS64439.1 - 0.042 13.6 0.5 8.6 6.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 ETS64439.1 - 0.054 13.4 0.1 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain Aldo_ket_red PF00248.16 ETS64440.1 - 6.8e-45 153.0 0.0 1.4e-44 152.0 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Exonuc_VII_S PF02609.11 ETS64440.1 - 0.074 12.8 0.1 6.6 6.5 0.0 2.8 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF1676 PF07898.8 ETS64440.1 - 0.1 12.9 0.1 0.23 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Pox_I6 PF04595.8 ETS64440.1 - 0.16 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family ketoacyl-synt PF00109.21 ETS64441.1 - 1.3e-45 155.8 0.7 1.3e-45 155.8 0.5 2.6 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETS64441.1 - 2.5e-14 53.1 0.2 1e-13 51.1 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain LytR_C PF13399.1 ETS64441.1 - 0.021 15.1 0.3 0.93 9.9 0.0 3.7 3 1 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator Lactamase_B_2 PF12706.2 ETS64442.1 - 2.3e-13 50.1 0.0 3.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS64442.1 - 5.6e-11 42.4 0.1 8.6e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Sel1 PF08238.7 ETS64443.1 - 1.1e-14 54.4 5.6 0.00012 22.5 0.0 5.4 6 0 0 6 6 6 3 Sel1 repeat Ipi1_N PF12333.3 ETS64444.1 - 5.3e-16 58.4 1.3 4.2e-10 39.4 0.0 5.0 5 0 0 5 5 5 3 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 ETS64444.1 - 0.028 14.9 4.3 0.033 14.6 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat Complex1_LYR PF05347.10 ETS64445.1 - 0.29 10.9 2.8 0.48 10.2 1.2 1.9 2 1 0 2 2 2 0 Complex 1 protein (LYR family) eIF2A PF08662.6 ETS64446.1 - 3.3e-42 144.4 0.0 3.7e-37 127.9 0.0 4.4 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 ETS64446.1 - 6.6e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS64446.1 - 2.8e-05 23.6 0.1 7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64446.1 - 0.00036 20.3 0.1 0.00093 19.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETS64446.1 - 0.0013 18.5 4.1 0.23 11.3 0.0 5.3 7 0 0 7 7 7 1 WD domain, G-beta repeat 4HB_MCP_1 PF12729.2 ETS64446.1 - 0.3 10.4 8.2 0.48 9.7 5.7 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Spb1_C PF07780.7 ETS64447.1 - 1.2e-70 237.3 31.6 1.2e-70 237.3 21.9 4.6 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 ETS64447.1 - 1.4e-52 178.2 0.0 3.1e-52 177.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 ETS64447.1 - 2.2e-51 173.5 9.6 2.2e-51 173.5 6.6 5.6 3 2 2 5 5 5 1 Domain of unknown function (DUF3381) DUF1751 PF08551.5 ETS64448.1 - 2.5e-28 98.2 3.7 6e-28 97.0 2.5 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 ETS64448.1 - 0.31 11.0 12.9 0.044 13.7 6.1 1.6 2 0 0 2 2 2 0 Rhomboid family LRR_6 PF13516.1 ETS64449.1 - 1.5e-13 49.2 8.5 0.22 11.7 0.0 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 ETS64449.1 - 7.3e-08 31.8 14.5 0.00033 20.2 0.9 6.3 5 3 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS64449.1 - 1.8e-05 24.1 3.7 14 6.1 0.0 6.8 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 ETS64449.1 - 4.4e-05 23.0 3.8 20 5.9 0.1 6.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 ETS64449.1 - 0.00013 21.6 11.3 0.033 13.9 0.2 5.7 4 2 1 5 5 5 1 Leucine rich repeat DUF2457 PF10446.4 ETS64449.1 - 4.7 5.8 16.6 7.7 5.1 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GTP_EFTU PF00009.22 ETS64450.1 - 1.9e-62 210.0 0.2 3e-62 209.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ETS64450.1 - 2.6e-36 123.7 0.0 7.1e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETS64450.1 - 1e-21 76.5 0.0 2.3e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 ETS64450.1 - 1.4e-13 50.4 0.0 3.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 ETS64450.1 - 2.7e-13 49.8 0.0 7.9e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS64450.1 - 4.8e-06 26.5 0.1 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Lectin_N PF03954.9 ETS64452.1 - 0.0063 15.9 0.9 0.13 11.6 0.1 2.4 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain DUF3508 PF12018.3 ETS64452.1 - 0.053 12.5 0.1 0.11 11.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) DUF651 PF04895.7 ETS64452.1 - 0.16 11.5 1.0 0.38 10.3 0.1 2.0 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) APG6 PF04111.7 ETS64452.1 - 0.3 10.1 4.1 0.62 9.0 2.8 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40 PF00400.27 ETS64453.1 - 4e-21 74.0 9.9 3.5e-05 23.5 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat HemX PF04375.9 ETS64454.1 - 0.007 15.0 0.1 0.0078 14.8 0.1 1.1 1 0 0 1 1 1 1 HemX DUF4250 PF14056.1 ETS64454.1 - 0.081 12.6 0.7 7 6.4 0.1 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4250) PEX11 PF05648.9 ETS64455.1 - 1.3e-66 224.1 2.4 1.4e-66 223.9 1.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Zn_clus PF00172.13 ETS64456.1 - 4.6e-06 26.4 15.3 8.7e-06 25.5 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tautomerase_3 PF14832.1 ETS64457.1 - 5.4e-41 139.7 0.0 6.3e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme DBD_Tnp_Mut PF03108.10 ETS64457.1 - 0.012 15.1 0.1 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 MuDR family transposase RNA_pol_Rpb6 PF01192.17 ETS64458.1 - 2.6e-24 84.7 0.2 3.5e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 adh_short PF00106.20 ETS64459.1 - 1.6e-12 47.7 0.7 2.3e-12 47.1 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS64459.1 - 4.1e-08 33.2 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS64459.1 - 0.0066 16.1 0.4 0.013 15.1 0.3 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS64459.1 - 0.025 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Barstar PF01337.13 ETS64459.1 - 0.05 13.4 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) His_Phos_2 PF00328.17 ETS64460.1 - 4e-43 148.0 0.0 5.6e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ski_Sno PF02437.12 ETS64460.1 - 0.12 11.8 0.0 5.2 6.6 0.0 3.1 4 0 0 4 4 4 0 SKI/SNO/DAC family MFS_1 PF07690.11 ETS64461.1 - 9.5e-29 100.1 41.4 1.5e-28 99.5 28.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.10 ETS64461.1 - 1.7 8.9 11.9 1.8 8.8 0.2 4.5 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Epimerase PF01370.16 ETS64462.1 - 4.7e-12 45.8 0.0 1.1e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS64462.1 - 2.9e-08 32.7 0.0 7.7e-08 31.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS64462.1 - 3.8e-08 32.5 0.0 4.8e-07 28.9 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS64462.1 - 7e-07 29.4 1.2 6.5e-06 26.2 0.6 2.5 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 ETS64462.1 - 0.00073 19.4 1.3 0.0021 18.0 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ETS64462.1 - 0.0026 17.0 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 ETS64462.1 - 0.0078 15.1 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETS64462.1 - 0.02 13.7 0.0 0.43 9.4 0.0 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain KR PF08659.5 ETS64462.1 - 0.034 13.7 1.1 0.11 12.1 0.8 1.8 1 1 0 1 1 1 0 KR domain Zn_clus PF00172.13 ETS64463.1 - 5.3e-07 29.4 10.6 1e-06 28.4 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS64463.1 - 0.0094 14.8 0.9 0.014 14.3 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF367 PF04034.8 ETS64465.1 - 7.2e-43 145.2 0.0 1e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 ETS64465.1 - 5e-15 54.7 0.1 8.4e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI ICL PF00463.16 ETS64466.1 - 3.9e-245 814.0 0.7 4.8e-245 813.7 0.5 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 ETS64466.1 - 1.4e-09 37.5 0.1 2.9e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 ETS64466.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain ABC2_membrane PF01061.19 ETS64467.1 - 1.1e-43 148.9 20.1 1.7e-43 148.2 14.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 ETS64467.1 - 9.1e-23 81.0 0.0 1.6e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 ETS64467.1 - 8.9e-07 28.2 15.1 8.9e-07 28.2 10.5 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 ETS64467.1 - 8.8e-05 22.6 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS64467.1 - 0.00051 19.4 0.0 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS64467.1 - 0.0014 18.6 1.3 0.0051 16.8 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_15 PF13175.1 ETS64467.1 - 0.0056 15.7 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETS64467.1 - 0.011 15.8 0.0 0.13 12.3 0.0 2.7 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 ETS64467.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 ETS64467.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETS64467.1 - 0.046 13.3 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETS64467.1 - 0.075 13.8 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS64467.1 - 0.083 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETS64467.1 - 0.091 12.3 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 ETS64467.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETS64467.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF87 PF01935.12 ETS64467.1 - 0.23 11.2 0.3 0.46 10.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 BTB PF00651.26 ETS64468.1 - 1.5e-08 34.5 0.0 0.00029 20.7 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain CWC25 PF12542.3 ETS64469.1 - 1.3e-25 89.6 1.3 1.3e-25 89.6 0.9 4.3 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 ETS64469.1 - 1e-12 47.8 12.8 1e-12 47.8 8.9 4.6 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR RNA_pol_Rpb2_6 PF00562.23 ETS64470.1 - 1.3e-124 415.9 0.3 2.7e-124 414.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 ETS64470.1 - 2e-66 222.8 0.0 3e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 ETS64470.1 - 2.5e-49 167.2 0.0 6.9e-49 165.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 ETS64470.1 - 2.5e-27 94.9 0.0 1.2e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 ETS64470.1 - 9.7e-24 82.9 0.6 3e-23 81.4 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 ETS64470.1 - 3.8e-22 77.8 0.0 8.9e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 ETS64470.1 - 5.7e-19 67.8 0.3 1.3e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 ETS64470.1 - 0.047 13.5 0.3 0.099 12.4 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Acetyltransf_1 PF00583.19 ETS64472.1 - 2.7e-10 40.1 0.0 3.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETS64472.1 - 3.6e-07 29.8 0.0 6.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 ETS64472.1 - 9.9e-05 22.4 0.0 0.00019 21.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS64472.1 - 0.0015 18.4 0.2 0.0024 17.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS64472.1 - 0.06 13.4 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Prenyltrans PF00432.16 ETS64473.1 - 3.4e-49 164.0 9.2 3.9e-11 42.3 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETS64473.1 - 4.1e-44 149.5 0.0 1.2e-11 45.0 0.0 3.6 1 1 5 6 6 6 6 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS64473.1 - 1.4e-08 34.7 0.0 8.1e-07 29.0 0.0 2.9 1 1 2 3 3 3 1 Prenyltransferase-like RRM_6 PF14259.1 ETS64474.1 - 6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS64474.1 - 8.7e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64474.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase02_C PF12123.3 ETS64474.1 - 0.081 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase AlaDh_PNT_N PF05222.10 ETS64475.1 - 9.4e-27 93.6 0.0 1.5e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 ETS64475.1 - 4.1e-07 29.7 0.0 7.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_L32p PF01783.18 ETS64476.1 - 2.7e-13 49.8 6.1 3.7e-13 49.4 4.2 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.1 ETS64476.1 - 0.039 13.1 0.7 0.063 12.5 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 ETS64476.1 - 0.33 10.7 2.6 0.52 10.1 1.8 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Lung_7-TM_R PF06814.8 ETS64477.1 - 5.3e-52 176.6 15.6 1.3e-51 175.3 10.8 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor PAP2 PF01569.16 ETS64478.1 - 1.3e-28 99.2 1.9 1.3e-28 99.2 1.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily Colicin_V PF02674.11 ETS64478.1 - 0.01 15.6 0.4 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 Colicin V production protein TPPK_C PF12555.3 ETS64478.1 - 0.062 13.0 0.7 0.062 13.0 0.5 3.5 3 1 0 3 3 3 0 Thiamine pyrophosphokinase C terminal DUF4006 PF13179.1 ETS64478.1 - 0.18 11.3 0.4 0.68 9.5 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF4006) QRPTase_C PF01729.14 ETS64479.1 - 6.8e-49 165.6 0.5 1e-48 165.0 0.4 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 ETS64479.1 - 2.5e-21 75.2 0.0 7.5e-21 73.7 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain TP6A_N PF04406.9 ETS64479.1 - 9.4e-17 60.4 0.0 1.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 ETS64479.1 - 0.0052 16.6 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) DUF1341 PF07071.6 ETS64479.1 - 0.018 14.5 0.1 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) Glyco_hydro_18 PF00704.23 ETS64480.1 - 5.6e-99 331.8 6.6 7.3e-99 331.4 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UTP15_C PF09384.5 ETS64481.1 - 3.4e-48 163.0 0.0 5e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 ETS64481.1 - 4.1e-35 118.3 4.0 2e-10 40.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 ETS64481.1 - 0.0017 16.5 0.0 0.86 7.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ThuA PF06283.6 ETS64482.1 - 4.4e-70 235.7 2.4 6e-70 235.3 1.7 1.2 1 0 0 1 1 1 1 Trehalose utilisation Sfi1 PF08457.5 ETS64485.1 - 1.1e-26 93.4 127.0 1.7e-19 69.6 64.3 3.7 1 1 2 3 3 3 3 Sfi1 spindle body protein ABC_tran PF00005.22 ETS64486.1 - 3.6e-47 160.0 0.0 5.2e-26 91.5 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETS64486.1 - 3.6e-16 59.9 0.1 0.01 15.8 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 ETS64486.1 - 8.1e-12 44.8 0.2 0.00037 19.8 0.0 3.4 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 ETS64486.1 - 3.4e-08 33.0 0.6 6.8e-08 32.0 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 ETS64486.1 - 1.9e-06 27.2 0.5 0.053 13.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETS64486.1 - 5.7e-06 26.2 0.0 0.014 15.3 0.0 3.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_15 PF13175.1 ETS64486.1 - 6.6e-06 25.4 0.1 0.22 10.5 0.1 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 ETS64486.1 - 1.9e-05 25.1 4.0 0.077 13.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 ETS64486.1 - 3.1e-05 24.4 1.8 0.018 15.5 0.0 3.6 3 1 0 3 3 2 1 Miro-like protein AAA_28 PF13521.1 ETS64486.1 - 8.9e-05 22.5 0.3 0.2 11.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 ETS64486.1 - 0.00025 20.6 1.1 1.7 7.9 0.1 4.2 4 0 0 4 4 4 1 AAA-like domain DUF87 PF01935.12 ETS64486.1 - 0.00062 19.6 0.1 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 ETS64486.1 - 0.00092 18.4 0.1 0.029 13.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 ETS64486.1 - 0.001 17.9 0.7 0.16 10.7 0.1 2.7 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 ETS64486.1 - 0.0012 18.9 0.1 4.5 7.4 0.0 4.0 5 0 0 5 5 4 0 AAA domain SbcCD_C PF13558.1 ETS64486.1 - 0.0017 18.2 0.0 0.28 11.1 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Tudor-knot PF11717.3 ETS64486.1 - 0.0018 17.9 0.7 0.0042 16.7 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_17 PF13207.1 ETS64486.1 - 0.0018 19.0 0.2 1.3 9.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 ETS64486.1 - 0.0019 18.1 0.0 0.85 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain CLASP_N PF12348.3 ETS64486.1 - 0.0043 16.4 0.1 11 5.3 0.0 3.6 3 0 0 3 3 3 0 CLASP N terminal AAA_25 PF13481.1 ETS64486.1 - 0.011 15.1 0.8 2.6 7.4 0.0 3.6 4 0 0 4 4 3 0 AAA domain MobB PF03205.9 ETS64486.1 - 0.012 15.3 0.1 2 8.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arm PF00514.18 ETS64486.1 - 0.023 14.5 0.6 0.14 12.0 0.2 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat NACHT PF05729.7 ETS64486.1 - 0.033 13.8 0.2 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 ETS64486.1 - 0.036 13.7 0.1 7.6 6.1 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase Dynamin_N PF00350.18 ETS64486.1 - 0.037 13.8 0.0 0.39 10.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 ETS64486.1 - 0.055 13.4 3.2 2.4 8.0 0.1 3.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 ETS64486.1 - 0.056 13.7 0.4 8.2 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.22 ETS64486.1 - 0.076 12.4 0.2 3.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 ETS64486.1 - 0.094 12.1 0.1 12 5.3 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 ETS64486.1 - 0.12 12.6 0.0 6.4 7.0 0.0 3.5 3 0 0 3 3 3 0 RNA helicase DUF3720 PF12517.3 ETS64486.1 - 0.27 11.9 7.8 0.094 13.4 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) HEAT_EZ PF13513.1 ETS64486.1 - 0.34 11.4 13.0 5.3 7.6 0.0 5.6 4 2 2 6 6 6 0 HEAT-like repeat GATA PF00320.22 ETS64487.1 - 4.1e-18 64.4 1.8 8.4e-18 63.4 1.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 ETS64487.1 - 5e-14 51.5 2.6 9.9e-14 50.6 1.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TRAPPC9-Trs120 PF08626.6 ETS64488.1 - 2.7e-73 246.9 0.0 5.2e-58 196.3 0.0 3.0 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF155 PF02582.9 ETS64489.1 - 2.6e-55 187.0 0.0 4.4e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ank_2 PF12796.2 ETS64490.1 - 1.3e-34 118.4 2.5 5e-10 39.5 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 ETS64490.1 - 1.9e-34 118.5 0.4 3.4e-34 117.7 0.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank PF00023.25 ETS64490.1 - 7.7e-29 98.0 6.6 2.3e-07 30.2 0.2 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 ETS64490.1 - 5.9e-26 90.3 11.2 5.1e-08 33.2 0.2 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS64490.1 - 3.7e-24 84.2 6.1 4.7e-09 36.2 0.0 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS64490.1 - 2e-19 67.7 1.4 9.5e-05 22.2 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat Adaptin_N PF01602.15 ETS64491.1 - 4.1e-137 457.6 10.6 5.2e-137 457.3 7.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETS64491.1 - 6.5e-26 91.2 5.7 1.8e-24 86.5 0.9 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETS64491.1 - 2.9e-15 56.3 13.8 1e-09 38.5 0.4 5.2 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 ETS64491.1 - 7.9e-10 37.9 1.3 0.016 15.2 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat CLASP_N PF12348.3 ETS64491.1 - 0.00012 21.5 0.2 2.5 7.4 0.0 3.6 2 1 1 3 3 3 2 CLASP N terminal Cnd3 PF12719.2 ETS64491.1 - 0.00041 19.4 0.4 0.11 11.5 0.0 2.5 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 ETS64491.1 - 0.00079 19.1 2.3 0.58 10.0 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETS64491.1 - 0.0023 18.3 6.5 0.66 10.5 0.1 5.8 5 1 1 6 6 6 1 HEAT-like repeat Med13_N PF11597.3 ETS64492.1 - 0.23 10.1 17.8 0.4 9.3 12.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Collagen PF01391.13 ETS64492.1 - 2.6 7.6 15.3 6.5e+02 -0.1 10.6 2.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) COesterase PF00135.23 ETS64493.1 - 1.5e-96 324.2 0.0 2.1e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS64493.1 - 3.3e-12 46.4 0.2 5.6e-12 45.6 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS64493.1 - 0.00017 20.8 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS64493.1 - 0.01 15.5 3.0 0.028 14.1 0.5 2.5 2 1 1 3 3 3 0 Alpha/beta hydrolase family MIF4G PF02854.14 ETS64495.1 - 3.1e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain Ribosomal_S21 PF01165.15 ETS64496.1 - 1.1e-12 47.1 6.5 1.7e-12 46.5 4.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 RNA_capsid PF03035.9 ETS64496.1 - 0.04 13.7 1.5 0.17 11.6 0.3 1.9 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein Fungal_trans PF04082.13 ETS64498.1 - 3.5e-26 91.6 0.0 5.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS64498.1 - 1.5e-09 37.6 1.5 2.9e-09 36.6 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Solute_trans_a PF03619.11 ETS64500.1 - 2e-97 325.7 10.9 2.5e-97 325.5 7.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha eIF-1a PF01176.14 ETS64501.1 - 1.1e-27 95.2 0.1 1.6e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NOA36 PF06524.7 ETS64501.1 - 1.9 7.6 4.6 2.2 7.4 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein YIF1 PF03878.10 ETS64502.1 - 2.3e-78 262.6 0.5 3.2e-78 262.1 0.4 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 ETS64502.1 - 0.0048 16.4 12.3 0.015 14.7 8.6 1.8 1 1 0 1 1 1 1 Yip1 domain UCR_14kD PF02271.11 ETS64503.1 - 3.5e-40 135.9 1.3 4.3e-40 135.7 0.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Methyltransf_28 PF02636.12 ETS64504.1 - 2.2e-70 236.9 0.0 4.3e-70 235.9 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Amino_oxidase PF01593.19 ETS64504.1 - 4.1e-21 75.5 0.7 1.1e-20 74.1 0.5 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS64504.1 - 1.4e-11 44.2 0.0 3.8e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS64504.1 - 4.3e-10 39.0 0.0 1.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS64504.1 - 6.8e-06 24.8 0.0 0.0077 14.7 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 ETS64504.1 - 0.00021 21.1 0.1 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS64504.1 - 0.00046 20.3 0.0 1.4 8.9 0.0 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS64504.1 - 0.014 14.0 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS64504.1 - 0.019 14.8 0.0 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS64504.1 - 0.029 14.7 0.4 10 6.5 0.0 3.1 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS64504.1 - 0.044 12.8 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NtA PF03146.10 ETS64504.1 - 0.082 12.5 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Agrin NtA domain Fungal_trans PF04082.13 ETS64505.1 - 2.5e-08 33.1 0.1 2.5e-08 33.1 0.1 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS64505.1 - 8.6e-05 22.3 10.2 8.6e-05 22.3 7.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Daxx PF03344.10 ETS64505.1 - 0.00033 19.2 14.4 0.00033 19.2 10.0 3.9 4 0 0 4 4 4 1 Daxx Family Hist_deacetyl PF00850.14 ETS64506.1 - 2e-69 234.2 0.1 2.9e-69 233.7 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RNA12 PF10443.4 ETS64506.1 - 0.1 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein DEAD PF00270.24 ETS64507.1 - 7.1e-43 146.0 0.0 1.5e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 ETS64507.1 - 9.4e-21 73.1 0.3 2.5e-20 71.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 ETS64507.1 - 1.7e-19 69.4 0.0 3.3e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Utp21 PF04192.7 ETS64508.1 - 1e-53 181.8 0.0 1.8e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 ETS64508.1 - 3.1e-13 49.0 5.7 9e-05 22.2 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETS64508.1 - 0.0073 14.6 0.4 0.043 12.0 0.2 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 ETS64508.1 - 0.053 13.0 0.1 5.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.1 ETS64508.1 - 0.16 11.5 0.0 2.1 7.9 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Ribosomal_L18e PF00828.14 ETS64509.1 - 2e-22 79.9 0.0 3.1e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 TIP49 PF06068.8 ETS64510.1 - 2.8e-188 625.6 4.0 9.3e-123 409.8 1.0 2.0 1 1 1 2 2 2 2 TIP49 C-terminus AAA PF00004.24 ETS64510.1 - 2.5e-08 34.1 4.5 2.2e-05 24.6 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS64510.1 - 1.3e-06 27.6 3.4 0.00059 18.9 0.0 3.4 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 ETS64510.1 - 3.8e-06 25.9 0.4 6.9e-06 25.1 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 ETS64510.1 - 0.00033 19.8 1.9 0.0096 15.1 0.2 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETS64510.1 - 0.0017 18.1 1.0 0.85 9.3 0.1 3.4 3 2 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS64510.1 - 0.0034 17.5 0.7 4.3 7.4 0.1 3.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS64510.1 - 0.0043 17.0 0.0 0.02 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 ETS64510.1 - 0.0088 15.4 1.3 0.014 14.8 0.2 1.8 2 1 0 2 2 2 1 AAA domain Sipho_tail PF05709.6 ETS64510.1 - 0.022 13.9 0.1 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein Sigma54_activat PF00158.21 ETS64510.1 - 0.051 13.0 0.5 6.6 6.1 0.0 3.2 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.1 ETS64510.1 - 0.092 12.7 0.1 0.27 11.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 ETS64510.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 ETS64510.1 - 1 9.2 5.5 0.8 9.5 0.0 3.1 2 2 0 2 2 2 0 AAA domain (Cdc48 subfamily) COG4 PF08318.7 ETS64511.1 - 1.2e-56 191.8 0.0 8.8e-56 189.0 0.0 2.0 1 1 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.8 ETS64511.1 - 0.013 14.1 0.1 0.18 10.3 0.0 2.4 2 0 0 2 2 2 0 RINT-1 / TIP-1 family HSCB_C PF07743.8 ETS64511.1 - 6.1 7.3 9.1 29 5.1 0.6 3.8 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain Nuf2 PF03800.9 ETS64512.1 - 1.2e-42 145.3 0.1 1.2e-42 145.3 0.0 2.9 2 1 1 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 ETS64512.1 - 0.0014 17.8 4.3 0.0014 17.8 3.0 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein GM_CSF PF01109.12 ETS64512.1 - 0.0023 17.8 1.2 0.0023 17.8 0.9 2.9 2 1 1 3 3 3 1 Granulocyte-macrophage colony-stimulating factor DUF3437 PF11919.3 ETS64512.1 - 0.031 13.9 0.8 0.32 10.7 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) DotA PF11388.3 ETS64512.1 - 0.073 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Baculo_PEP_C PF04513.7 ETS64512.1 - 1.3 8.8 19.3 0.6 9.9 2.2 3.9 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 ETS64512.1 - 4.8 7.2 45.3 0.7 9.9 8.2 4.4 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_G PF04718.10 ETS64512.1 - 6.2 7.5 11.0 0.82 10.3 0.5 4.0 1 1 3 4 4 4 0 Mitochondrial ATP synthase g subunit Methyltransf_16 PF10294.4 ETS64513.1 - 1.8e-18 66.5 0.0 5.5e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 ETS64513.1 - 3.2e-05 23.7 0.0 5.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS64513.1 - 3.5e-05 24.3 0.0 5.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS64513.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.9 ETS64513.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 ETS64513.1 - 0.029 14.3 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 ETS64513.1 - 0.035 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 ETS64513.1 - 0.036 14.5 0.0 0.077 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 ETS64513.1 - 0.068 12.1 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UPF0146 PF03686.8 ETS64513.1 - 0.16 11.7 0.0 0.61 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_31 PF13847.1 ETS64513.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3466 PF11949.3 ETS64514.1 - 0.013 14.1 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Glutaredoxin PF00462.19 ETS64516.1 - 2.1e-18 66.0 0.0 1e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 ETS64516.1 - 3.5e-15 55.5 0.0 6.5e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ETS64516.1 - 0.0017 18.4 0.1 0.07 13.2 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 ETS64516.1 - 0.0026 17.5 0.0 0.075 12.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.6 ETS64516.1 - 0.0075 16.1 0.0 0.14 12.0 0.0 2.5 2 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 ETS64516.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.10 ETS64516.1 - 0.034 14.0 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_7 PF13899.1 ETS64516.1 - 0.094 12.7 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like ArsC PF03960.10 ETS64516.1 - 0.1 12.6 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 ArsC family Thioredoxin_2 PF13098.1 ETS64516.1 - 0.11 12.7 0.0 7.1 6.8 0.0 3.0 2 1 0 2 2 2 0 Thioredoxin-like domain RabGAP-TBC PF00566.13 ETS64517.1 - 3.4e-44 150.8 0.0 4.8e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Elongin_A PF06881.6 ETS64518.1 - 1.5e-33 115.4 0.2 2.4e-33 114.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-NADH-PPase PF09297.6 ETS64519.1 - 0.0035 16.8 0.8 0.0093 15.4 0.5 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 ETS64519.1 - 0.039 13.7 4.6 0.17 11.7 3.2 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.2 ETS64519.1 - 0.35 10.7 3.4 1.1 9.0 2.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 ETS64519.1 - 0.72 9.5 4.5 4.5 7.0 0.2 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS CM_2 PF01817.16 ETS64520.1 - 6.1e-08 32.6 0.1 2.1e-05 24.5 0.0 3.5 2 1 1 3 3 3 2 Chorismate mutase type II NIF PF03031.13 ETS64521.1 - 1.4e-19 70.2 0.0 2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 ETS64521.1 - 1.9e-05 23.9 0.0 3.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 ETS64521.1 - 0.1 12.8 0.2 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-like domain Kinesin PF00225.18 ETS64522.1 - 6e-113 376.9 0.0 6e-113 376.9 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF465 PF04325.8 ETS64522.1 - 4.6e-12 45.4 3.1 4.6e-12 45.4 2.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF465) Filament PF00038.16 ETS64522.1 - 0.28 10.5 79.8 0.0047 16.4 31.1 4.1 3 1 1 4 4 4 0 Intermediate filament protein YqeY PF09424.5 ETS64523.1 - 3.5e-14 52.8 1.7 3.5e-14 52.8 1.2 2.0 2 0 0 2 2 2 1 Yqey-like protein HBS1_N PF08938.5 ETS64523.1 - 3e-10 40.0 3.9 7.2e-10 38.8 2.7 1.6 1 0 0 1 1 1 1 HBS1 N-terminus DUF1296 PF06972.6 ETS64523.1 - 0.026 14.4 0.2 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) CM_2 PF01817.16 ETS64523.1 - 0.03 14.4 0.2 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Chorismate mutase type II DUF3365 PF11845.3 ETS64523.1 - 3.5 7.4 6.7 0.21 11.3 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) GTP_EFTU PF00009.22 ETS64524.1 - 2.6e-43 147.6 0.0 4e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS64524.1 - 1.5e-08 34.7 0.1 3.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS64524.1 - 2e-08 34.2 0.8 5.5e-08 32.8 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS64524.1 - 8.6e-06 25.6 0.0 2.1e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 ETS64524.1 - 1.2e-05 24.8 0.5 3.3e-05 23.4 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 ETS64524.1 - 0.033 13.3 0.0 1.8 7.7 0.0 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 ETS64524.1 - 0.047 14.1 0.0 0.44 11.0 0.0 2.3 1 1 0 1 1 1 0 Miro-like protein Septin PF00735.13 ETS64524.1 - 0.09 11.7 0.0 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 Septin HhH-GPD PF00730.20 ETS64525.1 - 9e-19 67.7 0.0 2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETS64525.1 - 1.1e-08 34.3 0.0 4.5e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 ETS64525.1 - 0.033 14.3 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DNA_pol_viral_N PF00242.12 ETS64525.1 - 8.7 5.2 14.6 17 4.3 10.1 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain OMPdecase PF00215.19 ETS64526.1 - 2.7e-75 252.6 0.0 3.3e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mit_ribos_Mrp51 PF11709.3 ETS64527.1 - 4.3e-13 49.1 0.3 9.7e-12 44.7 0.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Cyclin PF08613.6 ETS64528.1 - 9.1e-10 39.1 0.0 2.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Cyclin Gly-zipper_Omp PF13488.1 ETS64529.1 - 0.0028 17.2 1.1 0.0028 17.2 0.8 4.1 3 1 0 3 3 3 2 Glycine zipper Gly-zipper_YMGG PF13441.1 ETS64529.1 - 0.009 15.5 0.3 0.009 15.5 0.2 4.1 2 1 0 2 2 2 1 YMGG-like Gly-zipper Beta-APP PF03494.8 ETS64529.1 - 1.3 8.5 4.2 3.3 7.2 2.9 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Gly-zipper_OmpA PF13436.1 ETS64529.1 - 1.7 8.3 28.0 1.3 8.6 1.1 4.0 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain TRM PF02005.11 ETS64530.1 - 2.1e-116 388.9 0.0 8e-89 298.1 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Amino_oxidase PF01593.19 ETS64531.1 - 1.3e-15 57.5 0.0 3.2e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 ETS64531.1 - 3.7e-13 49.0 1.7 3.7e-12 45.8 1.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS64531.1 - 3.1e-12 46.3 0.4 1e-11 44.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS64531.1 - 5.1e-06 26.5 0.1 9.5e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS64531.1 - 5.9e-06 25.3 1.3 0.00023 20.1 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 ETS64531.1 - 2.1e-05 23.1 0.3 0.0006 18.4 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 ETS64531.1 - 0.00045 19.9 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 ETS64531.1 - 0.00073 19.8 6.5 0.031 14.6 0.2 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS64531.1 - 0.0013 17.9 0.0 0.0048 16.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 ETS64531.1 - 0.0016 17.8 0.8 0.0032 16.9 0.5 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 ETS64531.1 - 0.0031 16.6 1.1 0.0059 15.7 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS64531.1 - 0.0037 17.3 0.5 0.46 10.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS64531.1 - 0.017 14.8 2.3 0.038 13.7 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS64531.1 - 0.02 13.5 3.5 0.81 8.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_trans_4_4 PF13579.1 ETS64531.1 - 0.022 14.8 0.1 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain TrkA_N PF02254.13 ETS64531.1 - 0.036 14.0 0.2 0.08 12.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 ETS64531.1 - 0.037 13.1 0.3 0.074 12.1 0.2 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 ETS64531.1 - 0.067 13.4 0.3 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 ETS64531.1 - 0.07 13.1 0.5 0.17 11.8 0.4 1.7 1 0 0 1 1 1 0 NADH(P)-binding GMC_oxred_N PF00732.14 ETS64531.1 - 0.071 12.2 0.1 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Rossmann-like PF10727.4 ETS64531.1 - 0.078 12.7 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain F420_oxidored PF03807.12 ETS64531.1 - 0.093 13.1 0.3 0.27 11.6 0.2 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDI PF00996.13 ETS64531.1 - 0.15 10.3 0.3 1.1 7.5 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 ETS64531.1 - 0.2 11.3 0.4 0.48 10.0 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 ETS64531.1 - 0.2 10.5 1.4 0.27 10.1 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 ETS64531.1 - 0.7 8.6 3.9 0.3 9.9 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Zn_clus PF00172.13 ETS64532.1 - 4.5e-07 29.6 11.2 8.4e-07 28.7 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS64532.1 - 2.8e-06 26.3 0.2 1.2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain 4HBT PF03061.17 ETS64534.1 - 4e-09 36.4 0.0 7.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Amidohydro_5 PF13594.1 ETS64534.1 - 0.0026 17.5 0.1 0.0078 16.0 0.0 1.9 2 1 0 2 2 2 1 Amidohydrolase 4HBT_3 PF13622.1 ETS64534.1 - 0.1 12.2 0.0 0.35 10.5 0.0 1.6 1 1 0 2 2 2 0 Thioesterase-like superfamily Velvet PF11754.3 ETS64537.1 - 2.7e-25 89.1 0.0 6.5e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.3 ETS64538.1 - 2.4e-58 197.0 0.0 4.7e-58 196.1 0.0 1.5 1 0 0 1 1 1 1 Velvet factor UCH PF00443.24 ETS64541.1 - 1.4e-76 257.1 0.0 2.3e-76 256.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS64541.1 - 2.5e-17 63.2 0.0 2.4e-10 40.3 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 ETS64541.1 - 1.3e-16 60.7 0.0 3.9e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 ETS64541.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.18 ETS64541.1 - 0.1 12.0 0.1 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Zn-ribbon_8 PF09723.5 ETS64541.1 - 0.69 9.9 2.9 3.5 7.6 0.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain BCS1_N PF08740.6 ETS64542.1 - 5.9e-56 189.0 0.0 8.5e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 ETS64542.1 - 5.5e-17 62.2 0.0 9.2e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS64542.1 - 1.6e-05 25.6 0.0 3.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETS64542.1 - 0.00017 21.0 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS64542.1 - 0.0058 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETS64542.1 - 0.0058 15.5 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 ETS64542.1 - 0.023 14.4 0.0 0.14 11.9 0.0 2.4 1 1 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 ETS64542.1 - 0.023 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS64542.1 - 0.048 13.6 0.3 0.048 13.6 0.2 2.8 1 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 ETS64542.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 ETS64542.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 ETS64542.1 - 0.17 12.0 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS64542.1 - 0.24 10.4 0.0 0.57 9.2 0.0 1.6 1 0 0 1 1 1 0 KaiC ATP_bind_3 PF01171.15 ETS64543.1 - 1.1e-15 57.6 0.0 2.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF4428 PF14471.1 ETS64543.1 - 0.01 15.5 0.9 0.38 10.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) MU117 PF15474.1 ETS64543.1 - 0.038 14.4 0.5 1.4 9.4 0.1 2.6 2 0 0 2 2 2 0 Meiotically up-regulated gene family DUF2616 PF11077.3 ETS64543.1 - 2 7.8 6.7 2.4 7.5 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) WD40 PF00400.27 ETS64544.1 - 8.8e-54 177.5 22.1 1.2e-08 34.5 0.1 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 ETS64544.1 - 2.3e-06 26.0 3.9 0.057 11.5 0.1 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3315 PF11776.3 ETS64544.1 - 0.1 12.1 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) OST3_OST6 PF04756.8 ETS64545.1 - 2.6e-20 72.6 4.1 4.3e-20 71.8 2.8 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 ETS64545.1 - 5.3e-05 22.8 0.1 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin VIT1 PF01988.14 ETS64545.1 - 0.00016 21.2 3.2 0.0033 16.9 0.0 2.3 2 0 0 2 2 2 2 VIT family HlyIII PF03006.15 ETS64545.1 - 0.0044 16.4 6.3 0.024 14.0 0.7 2.4 2 0 0 2 2 2 2 Haemolysin-III related Dynamitin PF04912.9 ETS64546.1 - 8.2e-35 120.3 5.4 1.7e-33 116.0 3.7 2.3 1 1 0 1 1 1 1 Dynamitin Transp_cyt_pur PF02133.10 ETS64546.1 - 3.3e-30 105.0 26.5 5.7e-30 104.2 18.3 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fib_alpha PF08702.5 ETS64546.1 - 0.0023 18.0 0.2 0.0066 16.5 0.1 1.8 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Matrilin_ccoil PF10393.4 ETS64546.1 - 0.0057 15.9 3.7 0.11 11.8 0.1 3.7 3 0 0 3 3 3 1 Trimeric coiled-coil oligomerisation domain of matrilin Phage_Mu_F PF04233.9 ETS64546.1 - 0.0064 17.0 0.0 0.096 13.2 0.0 2.4 2 0 0 2 2 2 1 Phage Mu protein F like protein Snapin_Pallidin PF14712.1 ETS64546.1 - 0.031 14.5 2.2 0.13 12.6 1.5 2.1 1 0 0 1 1 1 0 Snapin/Pallidin DUF2937 PF11157.3 ETS64546.1 - 0.078 12.3 3.9 0.045 13.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FemAB PF02388.11 ETS64546.1 - 0.18 10.4 1.1 0.28 9.8 0.8 1.2 1 0 0 1 1 1 0 FemAB family 5_nucleotid PF05761.9 ETS64546.1 - 0.33 9.4 0.5 0.61 8.5 0.3 1.3 1 0 0 1 1 1 0 5' nucleotidase family DUF3584 PF12128.3 ETS64546.1 - 0.49 7.6 12.2 0.019 12.3 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Cortex-I_coil PF09304.5 ETS64546.1 - 1.1 9.2 9.8 0.13 12.3 3.0 2.2 3 0 0 3 3 2 0 Cortexillin I, coiled coil PilJ PF13675.1 ETS64546.1 - 1.4 9.2 19.1 0.25 11.6 1.5 4.0 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term V-SNARE PF05008.10 ETS64546.1 - 4.9 7.3 13.7 0.4 10.8 3.0 3.4 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.7 ETS64546.1 - 4.9 6.9 7.5 1.3 8.8 0.5 2.9 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADK PF00406.17 ETS64547.1 - 9.3e-47 158.6 0.0 1.3e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 ETS64547.1 - 5.2e-09 36.4 0.0 9.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS64547.1 - 4.9e-07 30.6 0.0 8.8e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS64547.1 - 8.7e-07 28.9 0.0 2.3e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 ETS64547.1 - 6.1e-05 22.4 0.2 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 ETS64547.1 - 0.008 15.2 0.0 0.019 14.0 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin DUF4202 PF13875.1 ETS64548.1 - 6.9e-64 214.8 0.1 1.4e-63 213.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF1754 PF08555.5 ETS64548.1 - 2.6e-16 59.9 10.2 2.6e-16 59.9 7.1 2.6 3 0 0 3 3 3 1 Eukaryotic family of unknown function (DUF1754) Methyltransf_23 PF13489.1 ETS64548.1 - 2.4e-15 56.6 0.0 5.1e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS64548.1 - 1.7e-12 47.6 0.0 1.3e-11 44.8 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS64548.1 - 8.7e-10 38.8 0.0 4.1e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS64548.1 - 1.4e-09 38.2 0.1 8.2e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS64548.1 - 3.1e-09 36.5 0.0 5.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS64548.1 - 1.7e-08 35.0 0.0 5.6e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS64548.1 - 3.7e-07 30.1 0.0 1.3e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 ETS64548.1 - 0.00043 21.0 0.0 0.002 18.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 ETS64548.1 - 0.0005 19.4 0.0 0.0013 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain eRF1_2 PF03464.10 ETS64549.1 - 2.7e-45 153.9 0.0 6.4e-45 152.7 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 ETS64549.1 - 2.4e-37 127.6 0.9 3.6e-37 127.0 0.1 1.8 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 ETS64549.1 - 3.8e-26 91.2 0.0 6.5e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 AAA PF00004.24 ETS64550.1 - 1.8e-56 189.9 0.0 1.9e-43 147.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 ETS64550.1 - 4.7e-25 87.4 0.2 1.1e-24 86.3 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_25 PF13481.1 ETS64550.1 - 2.3e-10 40.2 3.7 0.0058 16.0 0.0 4.3 2 2 2 4 4 4 3 AAA domain AAA_17 PF13207.1 ETS64550.1 - 7.2e-10 39.7 0.1 0.0017 19.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 ETS64550.1 - 5.2e-09 36.3 12.2 0.00028 20.9 1.5 4.7 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 ETS64550.1 - 7.1e-08 32.6 0.7 0.015 15.4 0.1 4.1 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.1 ETS64550.1 - 1e-06 28.6 0.0 0.059 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 ETS64550.1 - 1.6e-06 28.0 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS64550.1 - 4.1e-06 26.4 0.8 0.018 14.7 0.1 3.4 2 1 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 ETS64550.1 - 4.9e-06 26.8 0.0 0.058 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ETS64550.1 - 8.1e-06 25.0 0.4 0.041 12.9 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin Mg_chelatase PF01078.16 ETS64550.1 - 1.6e-05 24.1 0.4 0.14 11.2 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 ETS64550.1 - 1.8e-05 23.9 0.0 0.0095 14.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 ETS64550.1 - 1.8e-05 24.4 0.4 0.42 10.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 ETS64550.1 - 2.2e-05 23.6 0.0 0.003 16.6 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 ETS64550.1 - 2.9e-05 24.1 0.0 0.34 11.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 ETS64550.1 - 3.3e-05 23.9 0.0 0.091 12.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 ETS64550.1 - 8.5e-05 22.6 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 ETS64550.1 - 0.00024 20.5 0.0 0.7 9.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein SKI PF01202.17 ETS64550.1 - 0.00027 20.8 0.0 0.78 9.5 0.0 2.9 2 0 0 2 2 2 2 Shikimate kinase TIP49 PF06068.8 ETS64550.1 - 0.00059 18.6 0.0 0.09 11.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus Viral_helicase1 PF01443.13 ETS64550.1 - 0.0013 18.3 0.0 0.27 10.7 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 ETS64550.1 - 0.0019 17.8 1.8 2.1 8.0 0.1 3.8 3 1 0 3 3 3 1 NACHT domain UPF0079 PF02367.12 ETS64550.1 - 0.0023 17.5 0.0 0.51 9.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_2 PF07724.9 ETS64550.1 - 0.0036 17.2 0.0 0.047 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 ETS64550.1 - 0.0056 15.5 0.0 1.6 7.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Cytidylate_kin2 PF13189.1 ETS64550.1 - 0.0069 16.3 0.0 0.5 10.2 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.6 ETS64550.1 - 0.0075 15.8 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 ETS64550.1 - 0.01 15.5 2.0 0.29 10.7 0.0 3.4 3 1 0 3 3 3 0 Adenylylsulphate kinase KTI12 PF08433.5 ETS64550.1 - 0.018 14.2 1.0 0.26 10.4 0.0 2.8 3 1 0 3 3 2 0 Chromatin associated protein KTI12 KaiC PF06745.8 ETS64550.1 - 0.019 14.0 0.0 5.5 6.0 0.0 2.4 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.10 ETS64550.1 - 0.02 14.5 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 ETS64550.1 - 0.021 15.1 0.6 6.8 6.9 0.1 3.2 3 1 0 4 4 3 0 ABC transporter Zot PF05707.7 ETS64550.1 - 0.059 12.8 0.5 29 4.0 0.2 4.1 4 1 0 4 4 4 0 Zonular occludens toxin (Zot) Rad17 PF03215.10 ETS64550.1 - 0.067 11.8 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PhoH PF02562.11 ETS64550.1 - 0.084 12.0 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 ETS64550.1 - 0.21 11.1 1.7 4.2 6.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain Perilipin PF03036.11 ETS64551.1 - 5.6e-11 41.9 0.4 1e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Perilipin family AAA_32 PF13654.1 ETS64551.1 - 0.031 12.9 0.6 0.041 12.5 0.4 1.1 1 0 0 1 1 1 0 AAA domain LIF_OSM PF01291.12 ETS64551.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 LIF / OSM family p450 PF00067.17 ETS64552.1 - 6.1e-60 203.0 0.0 1.4e-52 178.7 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 HA2 PF04408.18 ETS64553.1 - 9.9e-26 89.7 0.0 4.1e-25 87.7 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETS64553.1 - 3.3e-22 78.4 0.0 1.7e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 ETS64553.1 - 3.9e-13 49.0 0.0 1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS64553.1 - 2e-08 33.9 0.0 4.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS64553.1 - 1.4e-06 28.5 0.1 4.5e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 ETS64553.1 - 0.0011 17.9 0.0 0.0026 16.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 ETS64553.1 - 0.004 16.9 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 ETS64553.1 - 0.0097 15.6 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase DUF2075 PF09848.4 ETS64553.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 ETS64553.1 - 0.012 15.5 0.1 0.076 12.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 ETS64553.1 - 0.016 14.6 0.1 0.044 13.2 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 ETS64553.1 - 0.02 15.1 0.3 0.065 13.5 0.0 2.1 2 0 0 2 2 1 0 ABC transporter KaiC PF06745.8 ETS64553.1 - 0.031 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_10 PF12846.2 ETS64553.1 - 0.035 13.5 0.1 7 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 ETS64553.1 - 0.035 14.1 0.1 0.22 11.5 0.0 2.4 3 0 0 3 3 1 0 Sigma-54 interaction domain NACHT PF05729.7 ETS64553.1 - 0.051 13.2 0.1 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 ETS64553.1 - 0.08 13.2 0.1 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Myosin_head PF00063.16 ETS64553.1 - 0.11 10.4 0.0 0.18 9.7 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) NB-ARC PF00931.17 ETS64553.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Miro PF08477.8 ETS64553.1 - 0.19 12.2 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SE PF08491.5 ETS64553.1 - 0.28 9.9 0.0 0.48 9.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase HMA PF00403.21 ETS64554.1 - 3.9e-15 55.7 0.4 6e-15 55.1 0.3 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain YtkA PF13115.1 ETS64554.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 YtkA-like Melibiase PF02065.13 ETS64557.1 - 4.4e-35 121.1 0.0 2e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Melibiase Raffinose_syn PF05691.7 ETS64557.1 - 9e-05 20.2 0.0 0.00015 19.4 0.0 1.3 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 PX PF00787.19 ETS64558.1 - 2e-08 33.9 0.3 6.6e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 PX domain NDUF_B4 PF07225.7 ETS64559.1 - 7.9e-05 22.4 0.1 8.7e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Retro_M PF02813.9 ETS64559.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral M domain DUF1777 PF08648.7 ETS64560.1 - 2.8e-29 102.1 29.6 4.5e-29 101.4 20.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 ETS64560.1 - 2.2 6.6 13.5 2.4 6.5 9.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PDH PF02153.12 ETS64561.1 - 3.4e-15 55.6 0.0 9.9e-15 54.1 0.0 1.7 2 0 0 2 2 2 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 ETS64561.1 - 4.3e-05 23.4 0.2 0.0001 22.1 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS64561.1 - 0.00018 21.8 0.1 0.001 19.4 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ETS64561.1 - 0.0045 16.1 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS64561.1 - 0.0046 17.0 0.1 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Remorin_C PF03763.8 ETS64561.1 - 0.022 14.2 2.3 0.043 13.3 1.6 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region ApbA PF02558.11 ETS64561.1 - 0.031 13.7 0.0 0.079 12.3 0.0 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PI3_PI4_kinase PF00454.22 ETS64562.1 - 4.6e-46 157.1 0.0 7.8e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 ETS64562.1 - 1e-28 100.0 0.1 2.9e-28 98.5 0.0 1.9 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 ETS64562.1 - 8.3e-09 34.7 0.1 2.9e-08 33.0 0.1 1.9 1 0 0 1 1 1 1 FATC domain FA_hydroxylase PF04116.8 ETS64563.1 - 2.2e-11 44.1 10.9 2.2e-11 44.1 7.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2208 PF09973.4 ETS64563.1 - 0.034 13.3 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF3437 PF11919.3 ETS64564.1 - 0.12 12.0 0.4 0.18 11.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Mis12 PF05859.7 ETS64565.1 - 1.8e-17 63.5 0.0 3.4e-17 62.6 0.0 1.6 1 1 0 1 1 1 1 Mis12 protein Proteasome PF00227.21 ETS64566.1 - 2.1e-35 121.7 0.0 2.5e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SAMP PF05924.6 ETS64566.1 - 0.066 12.3 0.8 0.12 11.5 0.5 1.4 1 0 0 1 1 1 0 SAMP Motif DUF2461 PF09365.5 ETS64567.1 - 1.3e-74 250.1 0.0 2.3e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) IFT57 PF10498.4 ETS64567.1 - 0.19 10.4 1.8 0.35 9.5 1.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BEX PF04538.7 ETS64567.1 - 3.6 7.8 9.0 16 5.7 0.4 2.6 1 1 1 2 2 2 0 Brain expressed X-linked like family Piwi PF02171.12 ETS64568.1 - 1.2e-76 257.6 0.0 1.6e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 ETS64568.1 - 7.3e-16 57.6 0.0 1.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 ETS64568.1 - 2.5e-08 33.1 0.0 7.2e-08 31.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) FoP_duplication PF13865.1 ETS64568.1 - 1.3 9.5 4.8 3.1 8.3 3.3 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 B3_4 PF03483.12 ETS64569.1 - 2.9e-26 91.9 0.1 4.9e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 ETS64569.1 - 7e-18 64.2 0.0 2.4e-15 56.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 ETS64569.1 - 0.047 12.8 0.0 8.6 5.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) WD40 PF00400.27 ETS64570.1 - 1e-12 47.3 10.6 0.0079 16.0 0.0 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat Daxx PF03344.10 ETS64570.1 - 0.00024 19.7 11.0 0.00024 19.7 7.6 3.6 3 0 0 3 3 3 2 Daxx Family CENP-T PF15511.1 ETS64570.1 - 0.00076 18.8 15.6 0.00076 18.8 10.8 3.2 2 1 1 3 3 3 2 Centromere kinetochore component CENP-T LETM1 PF07766.8 ETS64571.1 - 3.8e-95 317.9 2.5 3.8e-95 317.9 1.7 2.4 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 ETS64571.1 - 8e-07 29.1 0.3 7.6e-06 25.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 ETS64571.1 - 0.00014 21.4 0.4 0.0004 19.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS64571.1 - 0.00047 19.2 0.6 0.35 10.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 ETS64571.1 - 0.0092 15.7 0.6 8.4 6.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain RPA_C PF08784.6 ETS64571.1 - 0.05 14.0 0.6 0.05 14.0 0.4 2.3 2 0 0 2 2 2 0 Replication protein A C terminal DUF1682 PF07946.9 ETS64571.1 - 0.93 8.2 12.5 1.8 7.3 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TatD_DNase PF01026.16 ETS64572.1 - 4.1e-51 173.6 0.3 5.4e-51 173.2 0.2 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 ETS64572.1 - 0.0031 17.1 0.8 0.27 10.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase Rot1 PF10681.4 ETS64573.1 - 9.8e-68 227.6 1.8 1.3e-67 227.2 1.2 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal p31comet PF06581.7 ETS64574.1 - 0.037 12.8 0.9 0.37 9.6 0.1 2.5 3 0 0 3 3 3 0 Mad1 and Cdc20-bound-Mad2 binding Coatomer_WDAD PF04053.9 ETS64575.1 - 1.7e-138 462.1 0.0 2.8e-138 461.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 ETS64575.1 - 3.6e-80 269.5 0.0 3.6e-80 269.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 ETS64575.1 - 1.9e-53 176.5 7.3 5.7e-11 41.8 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF1712 PF08217.6 ETS64575.1 - 1.1e-08 33.8 0.0 1.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Clathrin PF00637.15 ETS64575.1 - 0.046 13.3 0.1 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS GDC-P PF02347.11 ETS64576.1 - 3.2e-182 605.9 0.0 5.1e-168 559.2 0.0 3.0 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 ETS64576.1 - 1.3e-07 31.0 0.1 2.6e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 ETS64576.1 - 0.0001 21.2 0.5 0.0003 19.6 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V ATP-synt_D PF01813.12 ETS64577.1 - 3.9e-67 225.6 2.7 5.4e-67 225.1 1.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit D TAF4 PF05236.9 ETS64577.1 - 0.025 13.8 8.0 0.046 13.0 5.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1510 PF07423.6 ETS64577.1 - 0.12 11.7 11.0 0.21 10.9 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sec62 PF03839.11 ETS64577.1 - 3 7.2 13.4 5.4 6.3 9.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Ydc2-catalyt PF09159.5 ETS64577.1 - 4.3 6.7 10.9 1.2 8.5 5.3 1.7 2 0 0 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 CDC45 PF02724.9 ETS64577.1 - 7.3 4.4 15.9 12 3.8 11.0 1.3 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.7 ETS64577.1 - 8.3 6.2 17.5 16 5.2 12.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 She9_MDM33 PF05546.6 ETS64578.1 - 5.3e-69 231.9 7.4 8.7e-69 231.2 5.1 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family Rep_fac-A_3 PF08661.6 ETS64579.1 - 1.2e-32 111.9 0.1 1.4e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1365 PF07103.6 ETS64580.1 - 7.6e-24 84.1 1.0 2.9e-17 62.5 0.3 4.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1365) SET PF00856.23 ETS64581.1 - 7.2e-11 42.6 0.0 1.8e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 SET domain Mito_carr PF00153.22 ETS64582.1 - 2.9e-58 193.5 3.8 1.7e-24 85.3 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein GvpK PF05121.7 ETS64582.1 - 0.63 9.8 0.0 1.2 8.9 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein K Sec10 PF07393.6 ETS64583.1 - 2e-82 277.5 0.0 6.1e-82 275.9 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 ETS64583.1 - 2.6e-05 23.8 0.1 7.7e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS64583.1 - 0.0097 15.5 0.1 0.025 14.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain Spo7 PF03907.8 ETS64584.1 - 7e-17 61.7 5.8 3.7e-16 59.3 4.0 1.8 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.4 ETS64584.1 - 0.023 14.6 2.4 0.037 14.0 0.2 2.0 2 0 0 2 2 2 0 Transmembrane protein 188 DUF2207 PF09972.4 ETS64584.1 - 0.16 10.5 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SOBP PF15279.1 ETS64584.1 - 3 8.1 6.5 4.8 7.4 4.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Rib_5-P_isom_A PF06026.9 ETS64585.1 - 1.6e-53 180.5 0.0 2.3e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 ETS64585.1 - 0.0099 15.5 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain NUC173 PF08161.7 ETS64586.1 - 9.1e-51 172.0 0.2 1.2e-49 168.4 0.0 2.8 3 1 0 3 3 3 1 NUC173 domain Cnd1 PF12717.2 ETS64586.1 - 0.0018 18.1 0.2 0.16 11.7 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 ETS64586.1 - 0.22 10.2 5.9 0.63 8.7 0.1 3.1 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF4604 PF15377.1 ETS64587.1 - 2.3e-17 63.6 24.0 6.5e-17 62.1 16.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) EHN PF06441.7 ETS64588.1 - 2.5e-29 101.4 0.2 8.3e-29 99.7 0.0 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 ETS64588.1 - 2.1e-08 33.9 1.6 5.6e-08 32.6 0.1 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS64588.1 - 7.5e-08 32.5 11.3 7.5e-08 32.5 7.8 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 ETS64588.1 - 3.3e-05 23.9 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF3359 PF11839.3 ETS64589.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) DUF1227 PF06777.6 ETS64590.1 - 5.7e-60 201.2 0.1 1e-59 200.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 ETS64590.1 - 1.8e-46 157.7 0.0 3.5e-41 140.5 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 Helicase_C_2 PF13307.1 ETS64590.1 - 3.2e-45 154.0 0.0 7.3e-45 152.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 ETS64590.1 - 0.0021 17.5 0.0 0.97 8.9 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 ETS64590.1 - 0.0054 16.5 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YtxC PF08812.6 ETS64590.1 - 0.069 12.6 0.4 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 YtxC-like family Mitofilin PF09731.4 ETS64590.1 - 0.12 11.0 0.4 0.2 10.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SNF2_N PF00176.18 ETS64590.1 - 0.17 10.6 0.0 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain ABC_tran PF00005.22 ETS64591.1 - 3.9e-44 150.2 0.1 1.1e-21 77.5 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETS64591.1 - 3.1e-16 60.2 0.1 0.0059 16.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 ETS64591.1 - 1.1e-11 44.4 2.2 0.2 10.8 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain HEAT_2 PF13646.1 ETS64591.1 - 1.6e-10 41.0 0.8 5.2e-06 26.6 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats AAA_29 PF13555.1 ETS64591.1 - 6.8e-10 38.3 0.4 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 ETS64591.1 - 9.2e-08 31.8 0.0 0.078 12.3 0.0 3.8 4 1 0 4 4 3 2 AAA-like domain AAA_17 PF13207.1 ETS64591.1 - 7.5e-07 29.9 0.0 0.0054 17.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain CLASP_N PF12348.3 ETS64591.1 - 1.2e-06 28.1 0.1 3.8e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 ETS64591.1 - 3.7e-06 26.5 1.2 0.016 15.2 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Miro PF08477.8 ETS64591.1 - 4.4e-06 27.1 0.0 0.03 14.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 ETS64591.1 - 4.4e-06 26.8 0.1 0.1 12.7 0.0 4.0 5 0 0 5 5 3 2 AAA domain SbcCD_C PF13558.1 ETS64591.1 - 8.4e-06 25.6 0.1 0.0055 16.6 0.0 3.5 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Chromo PF00385.19 ETS64591.1 - 1.1e-05 24.9 0.0 3.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_16 PF13191.1 ETS64591.1 - 3.7e-05 23.8 1.0 0.6 10.0 0.0 4.6 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.1 ETS64591.1 - 8.3e-05 22.9 0.2 0.04 14.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETS64591.1 - 9.5e-05 22.3 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 ETS64591.1 - 0.00024 20.3 1.0 8.5 5.3 0.0 4.5 5 0 0 5 5 5 0 AAA ATPase domain HEAT_EZ PF13513.1 ETS64591.1 - 0.00025 21.4 3.3 0.045 14.2 0.0 4.9 4 2 3 7 7 5 1 HEAT-like repeat NACHT PF05729.7 ETS64591.1 - 0.00026 20.6 0.1 0.53 9.9 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA PF00004.24 ETS64591.1 - 0.00029 21.0 0.1 3.2 7.9 0.0 4.7 5 1 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 ETS64591.1 - 0.00047 19.8 0.1 0.77 9.4 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETS64591.1 - 0.00054 19.8 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 ETS64591.1 - 0.00083 19.3 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS64591.1 - 0.00093 18.4 0.0 0.76 8.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 ETS64591.1 - 0.0012 18.3 0.1 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 ETS64591.1 - 0.0014 18.9 0.5 0.042 14.1 0.0 3.7 3 1 0 3 3 2 2 AAA domain NB-ARC PF00931.17 ETS64591.1 - 0.0023 16.8 0.1 1.3 7.7 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain RNA_helicase PF00910.17 ETS64591.1 - 0.0032 17.5 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 ETS64591.1 - 0.0044 16.8 6.5 0.18 11.5 0.1 3.8 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_25 PF13481.1 ETS64591.1 - 0.0046 16.3 0.1 4.7 6.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 ETS64591.1 - 0.0049 15.6 1.0 0.73 8.5 0.0 2.7 2 0 0 2 2 2 1 ArgK protein Arm PF00514.18 ETS64591.1 - 0.0084 15.9 0.3 15 5.5 0.0 4.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AAA_5 PF07728.9 ETS64591.1 - 0.018 14.7 5.6 19 4.9 0.0 5.1 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS64591.1 - 0.033 14.0 0.0 6.9 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 ETS64591.1 - 0.034 13.3 0.8 16 4.5 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 ETS64591.1 - 0.034 13.0 0.8 5.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 ETS64591.1 - 0.041 13.5 0.1 5.9 6.5 0.0 2.6 2 0 0 2 2 2 0 NTPase Vac14_Fab1_bd PF12755.2 ETS64591.1 - 0.088 13.1 0.0 5.4 7.4 0.0 2.8 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region cobW PF02492.14 ETS64591.1 - 0.11 11.9 1.5 13 5.1 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 ETS64591.1 - 0.16 10.6 4.4 3.6 6.1 0.0 2.5 3 0 0 3 3 2 0 G-protein alpha subunit DUF3584 PF12128.3 ETS64591.1 - 0.2 8.9 8.3 0.44 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) ATP_bind_1 PF03029.12 ETS64591.1 - 0.48 9.9 2.7 8.7 5.7 0.1 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 ETS64591.1 - 0.49 8.7 8.6 1.3 7.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain Arch_ATPase PF01637.13 ETS64591.1 - 2.6 7.6 11.4 6.6 6.3 0.6 4.1 4 1 0 4 4 3 0 Archaeal ATPase Dopey_N PF04118.9 ETS64592.1 - 1.1e-110 369.2 0.0 2.3e-110 368.2 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal RRM_1 PF00076.17 ETS64593.1 - 3e-16 58.7 0.0 4.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64593.1 - 1.9e-13 50.1 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64593.1 - 1.8e-10 40.4 0.0 3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ParD PF09386.5 ETS64593.1 - 0.077 13.1 0.1 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Antitoxin ParD Sporozoite_P67 PF05642.6 ETS64593.1 - 0.4 8.4 4.0 0.56 8.0 2.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lamp PF01299.12 ETS64593.1 - 3.5 6.6 6.7 0.9 8.6 1.5 1.9 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Ribosomal_S15 PF00312.17 ETS64594.1 - 5.8e-18 64.4 0.7 9.9e-18 63.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 bPH_6 PF10756.4 ETS64594.1 - 0.051 13.4 0.1 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Bacterial PH domain Vps51 PF08700.6 ETS64595.1 - 3.1e-18 65.3 0.4 8.9e-18 63.9 0.3 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 ETS64595.1 - 0.0011 18.8 0.5 0.0011 18.8 0.4 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 EXS PF03124.9 ETS64596.1 - 1.2e-84 284.3 17.8 1.6e-84 283.9 12.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 ETS64596.1 - 3.9e-47 161.3 0.2 1.5e-46 159.3 0.0 2.0 2 0 0 2 2 2 1 SPX domain Nucleoplasmin PF03066.10 ETS64596.1 - 1.4 8.3 5.8 2.9 7.4 4.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin HECT_2 PF09814.4 ETS64597.1 - 6.4e-40 136.9 0.0 1.2e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding hNIFK_binding PF12196.3 ETS64597.1 - 0.11 11.9 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK FH2 PF02181.18 ETS64598.1 - 4.7e-65 219.8 6.0 4.7e-65 219.8 4.2 2.7 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 ETS64598.1 - 9.2e-45 152.4 0.0 9.9e-44 149.1 0.0 2.4 1 1 1 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 ETS64598.1 - 3.2e-44 150.5 0.1 2.1e-43 147.9 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain CorA PF01544.13 ETS64598.1 - 4.3 6.2 11.2 0.89 8.5 0.4 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 ETS64598.1 - 4.7 6.7 20.4 0.095 12.2 6.1 2.8 2 1 0 2 2 2 0 IncA protein CorA PF01544.13 ETS64599.1 - 5.7e-11 41.9 0.4 7.8e-11 41.5 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TSGA13 PF14994.1 ETS64599.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Testis-specific gene 13 protein DUF972 PF06156.8 ETS64599.1 - 2.4 8.5 5.3 13 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) UreD PF01774.12 ETS64600.1 - 2e-56 190.8 0.2 3.3e-56 190.0 0.1 1.4 1 0 0 1 1 1 1 UreD urease accessory protein Transaldolase PF00923.14 ETS64601.1 - 4e-95 318.2 0.4 4.5e-95 318.0 0.2 1.0 1 0 0 1 1 1 1 Transaldolase Pro_isomerase PF00160.16 ETS64602.1 - 1.5e-46 158.4 0.0 1.7e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 ETS64603.1 - 1.1e-65 221.3 0.0 1.6e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64603.1 - 5.9e-29 100.9 0.0 8.1e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS64603.1 - 7.5e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS64603.1 - 0.024 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS64603.1 - 0.033 13.9 0.2 1.2 8.8 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3012 PF11216.3 ETS64603.1 - 0.046 13.3 0.2 6.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) adh_short PF00106.20 ETS64604.1 - 3.5e-20 72.5 2.7 3.3e-19 69.3 1.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS64604.1 - 3.9e-18 66.0 0.8 6.2e-17 62.1 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS64604.1 - 2.4e-08 33.8 3.5 1.5e-07 31.2 0.1 2.2 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 ETS64604.1 - 0.033 14.2 0.1 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribonuc_L-PSP PF01042.16 ETS64604.1 - 0.057 13.1 0.1 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Endoribonuclease L-PSP NAD_binding_10 PF13460.1 ETS64604.1 - 0.083 12.8 0.4 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 NADH(P)-binding Meth_synt_2 PF01717.13 ETS64605.1 - 9.3e-24 83.9 0.0 1.5e-23 83.3 0.0 1.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS64605.1 - 9.1e-08 31.7 0.0 0.028 13.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain BIR PF00653.16 ETS64606.1 - 2.2e-25 88.8 0.3 1.9e-20 73.0 0.3 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain SHQ1 PF04925.10 ETS64607.1 - 1.2e-34 119.4 0.0 2e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein WAPL PF07814.8 ETS64607.1 - 1.5e-08 33.8 1.6 5.6e-08 31.9 0.0 2.4 3 0 0 3 3 3 1 Wings apart-like protein regulation of heterochromatin SNF2_N PF00176.18 ETS64608.1 - 1.6e-27 96.0 0.0 1e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 ETS64608.1 - 1.4e-11 44.1 0.0 3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase ResIII PF04851.10 ETS64608.1 - 0.14 12.0 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 ETS64608.1 - 4.4 7.1 15.5 5.8 6.7 2.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain DUF3481 PF11980.3 ETS64609.1 - 5.1 6.9 6.1 3.2 7.6 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) SNF2_N PF00176.18 ETS64610.1 - 6.1e-68 228.8 0.1 8.6e-67 225.0 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS64610.1 - 4.3e-17 61.7 0.0 1.3e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETS64610.1 - 3.2e-12 45.8 2.0 8.5e-10 37.9 0.0 3.2 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 ETS64610.1 - 1.3e-08 34.9 0.6 7.8e-07 29.0 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETS64610.1 - 0.00043 20.4 0.4 2.6 8.1 0.0 3.9 3 0 0 3 3 3 2 AAA domain AT_hook PF02178.14 ETS64610.1 - 0.034 13.8 5.0 0.13 12.0 3.5 2.1 1 0 0 1 1 1 0 AT hook motif Aminotran_5 PF00266.14 ETS64611.1 - 3.9e-20 71.9 0.0 8.4e-20 70.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETS64611.1 - 0.00034 19.0 0.1 0.00069 17.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETS64611.1 - 0.0029 16.6 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 ETS64611.1 - 0.044 12.2 0.1 0.09 11.2 0.1 1.5 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain 3Beta_HSD PF01073.14 ETS64612.1 - 3.8e-57 193.1 0.0 1.1e-51 175.1 0.0 2.4 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS64612.1 - 6.3e-25 87.9 0.0 9.2e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS64612.1 - 5.5e-12 45.1 0.2 3.3e-11 42.5 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS64612.1 - 1.4e-09 38.1 0.1 4.4e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS64612.1 - 7.6e-07 28.3 0.1 1e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETS64612.1 - 0.00014 21.7 0.3 0.00031 20.6 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS64612.1 - 0.00058 18.8 0.1 0.0012 17.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 ETS64612.1 - 0.0032 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 ETS64612.1 - 0.021 14.5 0.3 0.059 13.0 0.2 1.8 1 1 0 1 1 1 0 KR domain ELFV_dehydrog PF00208.16 ETS64612.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_rhodopsin PF01036.13 ETS64613.1 - 1.1e-34 119.6 15.2 2.5e-24 85.8 4.9 2.1 1 1 0 2 2 2 2 Bacteriorhodopsin-like protein DUF1304 PF06993.7 ETS64613.1 - 1.1 9.0 7.4 1.5 8.5 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) EamA PF00892.15 ETS64614.1 - 2.2e-20 72.9 24.6 2.4e-11 43.7 3.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 ETS64614.1 - 0.0001 22.4 5.1 0.0001 22.4 3.5 3.2 2 1 0 3 3 3 2 Multidrug resistance efflux transporter MLANA PF14991.1 ETS64614.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A PAP2 PF01569.16 ETS64615.1 - 9.1e-16 57.7 3.6 1.7e-15 56.8 2.5 1.4 1 0 0 1 1 1 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.17 ETS64615.1 - 5.8e-11 41.9 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 ETS64615.1 - 0.0057 16.2 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain OTU PF02338.14 ETS64616.1 - 8.4e-19 68.3 0.0 1.9e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 ETS64616.1 - 0.00091 18.6 0.0 0.11 11.7 0.0 2.3 1 1 0 2 2 2 2 Peptidase C65 Otubain T2SM PF04612.7 ETS64616.1 - 0.4 10.4 3.4 0.51 10.1 1.1 2.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M HMGL-like PF00682.14 ETS64617.1 - 2.7e-71 239.9 0.4 4.7e-71 239.2 0.3 1.4 1 0 0 1 1 1 1 HMGL-like Alk_phosphatase PF00245.15 ETS64618.1 - 3e-91 306.2 0.1 3.7e-91 305.9 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Myosin_head PF00063.16 ETS64619.1 - 1.3e-228 760.5 4.6 2.2e-228 759.7 3.2 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 ETS64619.1 - 4.1e-43 147.0 0.0 7e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 ETS64619.1 - 9.3e-11 41.1 0.1 2.2e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS64619.1 - 5.1e-10 38.5 2.1 6.7e-10 38.1 0.3 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 ETS64619.1 - 1.6e-09 37.1 0.1 3.3e-08 32.9 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 ETS64619.1 - 0.0028 17.8 1.1 0.007 16.5 0.8 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 ETS64619.1 - 0.0035 17.4 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS64619.1 - 0.018 14.1 0.0 0.051 12.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 ETS64619.1 - 0.024 15.4 0.0 0.12 13.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 ETS64619.1 - 0.044 13.0 0.4 4.8 6.4 0.0 2.9 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 ETS64619.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 ETS64619.1 - 0.2 11.5 0.0 0.62 10.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain HA2 PF04408.18 ETS64620.1 - 2.2e-17 62.9 1.9 2.4e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS64620.1 - 2.2e-16 59.4 0.1 4.4e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS64620.1 - 1.9e-10 40.5 0.0 8.5e-10 38.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 ETS64620.1 - 3e-08 33.4 0.0 6.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 ETS64620.1 - 6.4e-05 23.0 0.0 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ETS64620.1 - 0.0042 16.2 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 ETS64620.1 - 0.0092 14.9 0.0 0.037 12.9 0.0 2.0 1 1 0 1 1 1 1 Type II/IV secretion system protein DUF494 PF04361.8 ETS64620.1 - 0.034 13.8 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) PhoH PF02562.11 ETS64620.1 - 0.1 11.8 0.4 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Astacin PF01400.19 ETS64621.1 - 1.6e-08 34.1 0.1 4.8e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) TMEM171 PF15471.1 ETS64621.1 - 0.0015 17.4 2.6 0.0029 16.4 1.8 1.4 1 0 0 1 1 1 1 Transmembrane protein family 171 Peptidase_M10 PF00413.19 ETS64621.1 - 0.0036 17.0 1.4 0.019 14.6 0.9 2.1 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 ETS64621.1 - 0.031 13.8 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Glyco_hydro_39 PF01229.12 ETS64623.1 - 4.6e-06 25.3 0.0 7.1e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Astacin PF01400.19 ETS64624.1 - 1.5e-09 37.5 0.3 4.6e-09 35.9 0.2 1.8 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 ETS64624.1 - 1.6e-06 27.8 2.0 0.0001 22.0 1.4 2.3 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 ETS64624.1 - 0.0002 21.0 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 ETS64624.1 - 0.032 13.7 1.3 0.072 12.6 0.9 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4390 PF14334.1 ETS64624.1 - 0.038 13.1 0.1 0.89 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) Reprolysin_5 PF13688.1 ETS64624.1 - 2.3 8.0 6.4 5.3 6.9 3.3 2.5 2 1 0 2 2 2 0 Metallo-peptidase family M12 DUF4267 PF14087.1 ETS64625.1 - 0.027 14.0 0.2 0.032 13.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) DUF1689 PF07954.6 ETS64625.1 - 0.078 12.8 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) MFS_1 PF07690.11 ETS64626.1 - 4.1e-13 48.7 24.0 4.1e-13 48.7 16.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PHAT PF09246.5 ETS64627.1 - 0.21 11.2 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 PHAT Sporozoite_P67 PF05642.6 ETS64628.1 - 0.2 9.5 2.9 0.35 8.6 2.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Melibiase PF02065.13 ETS64629.1 - 9.5e-32 110.1 0.1 7.8e-19 67.6 0.1 2.0 2 0 0 2 2 2 2 Melibiase Raffinose_syn PF05691.7 ETS64629.1 - 0.00045 17.8 0.1 0.00061 17.4 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Lactamase_B_5 PF14597.1 ETS64629.1 - 0.057 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Alginate_lyase PF05426.7 ETS64630.1 - 5.8e-12 45.5 5.3 1.4e-11 44.2 3.7 1.5 1 1 0 1 1 1 1 Alginate lyase COesterase PF00135.23 ETS64631.1 - 1.5e-98 330.8 0.0 2.3e-98 330.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS64631.1 - 8.1e-06 25.5 0.1 3.6e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS64631.1 - 0.028 13.6 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Alginate_lyase PF05426.7 ETS64632.1 - 0.082 12.2 2.9 0.19 11.0 1.9 1.8 1 1 0 1 1 1 0 Alginate lyase Glyco_hydro_88 PF07470.8 ETS64633.1 - 6.4e-13 48.4 0.1 1.4e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_32N PF00251.15 ETS64634.1 - 0.0013 18.1 0.6 0.18 11.1 0.5 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 ETS64634.1 - 0.0072 15.4 1.2 0.012 14.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 ETS64635.1 - 2.4e-33 115.3 24.7 3e-33 114.9 17.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS64636.1 - 1.3e-21 76.6 0.0 2.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS64636.1 - 1.1e-08 34.8 11.7 1.1e-08 34.8 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_28 PF00295.12 ETS64637.1 - 6.1e-10 38.5 0.0 4e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 ETS64637.1 - 0.016 14.9 4.8 0.5 10.0 3.3 2.7 1 1 0 1 1 1 0 Right handed beta helix region Alginate_lyase PF05426.7 ETS64638.1 - 2.1e-17 63.4 0.0 4.4e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Alginate lyase RTA1 PF04479.8 ETS64639.1 - 1e-33 116.7 7.6 1.4e-33 116.3 5.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 ETS64642.1 - 0.071 13.0 6.6 0.12 12.3 4.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 ETS64642.1 - 0.16 11.9 1.1 0.28 11.2 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF333 PF03891.10 ETS64643.1 - 2e-51 171.5 0.1 5.4e-25 86.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF333) m04gp34like PF12216.3 ETS64643.1 - 0.036 13.4 0.0 3.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Immune evasion protein CIDE-N PF02017.10 ETS64643.1 - 0.045 13.5 0.3 2.1 8.1 0.0 2.5 2 1 0 2 2 2 0 CIDE-N domain DUF466 PF04328.8 ETS64643.1 - 0.16 11.8 0.8 14 5.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF466) DUF3712 PF12505.3 ETS64644.1 - 4.1e-88 291.7 30.8 1.1e-15 57.7 0.1 9.2 11 0 0 11 11 11 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 ETS64644.1 - 2e-09 37.7 19.3 0.14 12.5 0.0 10.6 10 0 0 10 10 10 4 Late embryogenesis abundant protein Phage_integrase PF00589.17 ETS64645.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family GMC_oxred_N PF00732.14 ETS64646.1 - 1.3e-60 205.0 0.0 1.8e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS64646.1 - 2.4e-36 125.1 0.0 3.9e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS64646.1 - 2.8e-05 23.1 0.2 0.00043 19.2 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS64646.1 - 5.7e-05 22.1 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS64646.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS64646.1 - 0.07 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 ETS64646.1 - 0.096 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 ETS64646.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family ELFV_dehydrog PF00208.16 ETS64647.1 - 8.9e-80 267.7 2.0 1.2e-79 267.3 1.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ETS64647.1 - 3.7e-44 149.4 0.0 7.4e-44 148.4 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 ETS64647.1 - 0.079 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding HnRNPA1 PF11627.3 ETS64647.1 - 0.48 10.6 3.8 3.2 8.0 0.5 2.9 2 0 0 2 2 2 0 Nuclear factor hnRNPA1 B12D PF06522.6 ETS64648.1 - 1.1e-18 66.7 0.1 1.4e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PS_Dcarbxylase PF02666.10 ETS64649.1 - 1.7e-49 167.8 0.0 3.3e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 ETS64649.1 - 1.1e-31 108.5 0.2 7.2e-14 51.3 0.0 3.7 3 0 0 3 3 3 3 C2 domain EF-hand_7 PF13499.1 ETS64649.1 - 9.4e-07 28.8 0.4 2e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETS64649.1 - 9.8e-05 21.9 1.6 0.33 10.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain Daxx PF03344.10 ETS64649.1 - 0.095 11.1 2.7 0.17 10.3 1.9 1.3 1 0 0 1 1 1 0 Daxx Family Upf2 PF04050.9 ETS64649.1 - 0.15 11.8 4.7 0.29 10.8 3.3 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 CEP76-C2 PF15627.1 ETS64649.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain BUD22 PF09073.5 ETS64649.1 - 1.2 8.0 13.5 2.1 7.3 9.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 ETS64649.1 - 1.3 8.1 9.9 2.1 7.5 6.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETS64649.1 - 2.2 6.1 6.3 3.4 5.6 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETS64649.1 - 3.7 5.3 14.4 5.4 4.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1764 PF08576.5 ETS64650.1 - 2.8e-15 56.9 10.7 6.7e-11 42.8 7.4 2.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) DUF3375 PF11855.3 ETS64650.1 - 0.13 11.0 1.6 0.16 10.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Mif2_N PF15624.1 ETS64650.1 - 0.23 12.0 13.5 0.32 11.6 9.4 1.3 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal TPR_11 PF13414.1 ETS64651.1 - 3.9e-11 42.4 3.6 1.5e-08 34.1 2.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETS64651.1 - 8.7e-09 34.6 2.1 9.2e-06 25.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS64651.1 - 3.3e-08 32.8 5.3 0.00011 21.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS64651.1 - 9.6e-07 29.3 7.8 5e-06 27.0 4.7 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS64651.1 - 9.5e-05 22.2 4.8 1.5e+02 2.3 0.3 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS64651.1 - 0.00023 21.2 0.2 0.00066 19.7 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS64651.1 - 0.00033 20.9 7.8 0.0025 18.1 2.4 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS64651.1 - 0.0013 18.7 0.6 0.099 12.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS64651.1 - 0.0044 16.7 0.5 0.017 14.8 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS64651.1 - 0.0046 17.4 6.1 0.0052 17.3 1.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS64651.1 - 0.012 16.0 7.7 0.13 12.8 0.2 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS64651.1 - 0.018 15.4 0.9 0.14 12.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETS64651.1 - 0.051 13.4 1.9 0.11 12.3 1.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS64651.1 - 0.054 13.2 1.5 3.6 7.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 ETS64651.1 - 0.071 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 ETS64651.1 - 0.13 12.1 3.7 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PALP PF00291.20 ETS64652.1 - 2.8e-54 184.4 0.0 9.2e-53 179.4 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AA_permease_2 PF13520.1 ETS64653.1 - 2e-50 171.6 45.0 2.4e-50 171.3 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS64653.1 - 2.7e-19 68.8 46.6 6.1e-19 67.7 32.3 1.5 1 1 0 1 1 1 1 Amino acid permease ADH_N PF08240.7 ETS64654.1 - 6.9e-30 103.0 0.2 1.5e-29 101.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS64654.1 - 2e-25 88.8 0.6 3.1e-25 88.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS64654.1 - 0.00092 20.1 0.4 0.0018 19.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Lipase_GDSL_2 PF13472.1 ETS64654.1 - 0.098 12.7 0.0 0.4 10.8 0.0 1.7 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Trs65 PF12735.2 ETS64655.1 - 0.00022 20.6 0.0 0.096 11.9 0.0 2.5 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 Aminotran_4 PF01063.14 ETS64656.1 - 3.7e-17 62.5 0.0 5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV vATP-synt_AC39 PF01992.11 ETS64657.1 - 3e-97 325.7 0.0 3.4e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SEN1_N PF12726.2 ETS64658.1 - 3e-126 422.3 0.3 3.9e-126 421.9 0.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 ETS64658.1 - 5.2e-67 225.8 0.1 1.4e-66 224.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 ETS64658.1 - 2e-61 206.9 0.0 3.9e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS64658.1 - 2.8e-12 46.2 0.5 1.3e-11 44.1 0.3 2.2 1 0 0 1 1 1 1 Part of AAA domain Fungal_trans PF04082.13 ETS64658.1 - 0.00014 20.8 0.0 0.00027 19.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Viral_helicase1 PF01443.13 ETS64658.1 - 0.00016 21.3 0.7 0.67 9.4 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Zn_clus PF00172.13 ETS64658.1 - 0.00023 21.0 9.5 0.00023 21.0 6.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_25 PF13481.1 ETS64658.1 - 0.0027 17.1 0.1 0.0082 15.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 ETS64658.1 - 0.0058 16.7 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 ETS64658.1 - 0.33 11.1 1.7 9 6.4 0.1 3.6 4 0 0 4 4 4 0 AAA domain Sugar_tr PF00083.19 ETS64659.1 - 1.1e-31 109.8 32.6 1.7e-30 105.9 22.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS64659.1 - 7.7e-18 64.3 47.7 1.6e-10 40.2 12.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WTF PF03303.8 ETS64659.1 - 0.14 11.5 0.2 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 WTF protein Aldo_ket_red PF00248.16 ETS64661.1 - 7.6e-60 202.1 0.0 1.1e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Transket_pyr PF02779.19 ETS64661.1 - 3.3e-40 137.4 0.0 5.6e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ETS64661.1 - 9.1e-30 103.1 0.0 2.8e-29 101.5 0.0 1.8 1 1 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_L10 PF00466.15 ETS64661.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 WD40 PF00400.27 ETS64662.1 - 1.4e-36 123.0 17.4 2.3e-09 36.7 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETS64662.1 - 6.4e-06 26.0 0.0 0.022 14.4 0.0 3.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETS64662.1 - 0.00028 19.1 0.7 0.00051 18.3 0.5 1.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETS64662.1 - 0.053 11.8 1.0 0.53 8.5 0.3 2.0 1 1 0 2 2 2 0 Cytochrome D1 heme domain NDK PF00334.14 ETS64663.1 - 4e-57 191.7 0.0 4.9e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 ETS64663.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ AOX PF01786.12 ETS64664.1 - 5.4e-93 310.1 0.3 6.6e-93 309.8 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Ribosomal_L34e PF01199.13 ETS64665.1 - 2.1e-36 124.0 6.1 2.6e-36 123.7 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 ETS64665.1 - 0.0092 15.5 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c7 FhuF_C PF11575.3 ETS64665.1 - 4.4 7.0 5.6 8.8 6.0 0.2 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Ribosomal_L6 PF00347.18 ETS64666.1 - 7.1e-21 74.4 0.7 1.6e-13 50.9 0.0 3.6 3 1 0 3 3 3 2 Ribosomal protein L6 R3H-assoc PF13902.1 ETS64667.1 - 0.01 15.8 0.3 0.01 15.8 0.2 2.3 2 1 1 3 3 3 0 R3H-associated N-terminal domain DUF605 PF04652.11 ETS64668.1 - 2.7 7.2 14.6 3.4 6.9 10.1 1.2 1 0 0 1 1 1 0 Vta1 like DUF953 PF06110.6 ETS64669.1 - 2.3e-13 49.6 0.0 2.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 ETS64669.1 - 3.1e-05 23.6 0.1 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 ETS64669.1 - 0.003 17.1 0.1 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin UDG PF03167.14 ETS64670.1 - 1.7e-22 79.5 1.0 1.2e-13 50.7 0.0 2.7 2 1 1 3 3 3 2 Uracil DNA glycosylase superfamily Aldedh PF00171.17 ETS64671.1 - 2.2e-184 613.0 0.5 2.5e-184 612.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS64671.1 - 3.4e-05 22.7 0.0 5.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS64671.1 - 0.00078 18.7 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) OPT PF03169.10 ETS64672.1 - 3.3e-99 333.0 43.0 6.4e-99 332.1 29.8 1.4 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DNase_NucA_NucB PF14040.1 ETS64673.1 - 8.5e-30 103.2 2.6 1.1e-29 102.8 1.8 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Me-amine-dh_L PF02975.9 ETS64673.1 - 0.0024 17.8 3.8 0.0024 17.8 2.6 1.9 1 1 1 2 2 2 1 Methylamine dehydrogenase, L chain ADH_N PF08240.7 ETS64674.1 - 4.9e-23 80.9 0.3 8.3e-23 80.2 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS64674.1 - 2.3e-15 56.2 0.0 3.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase XdhC_C PF13478.1 ETS64674.1 - 0.029 14.6 0.0 0.084 13.1 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 ETS64674.1 - 0.029 13.5 0.0 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS64674.1 - 0.065 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 ETS64674.1 - 0.074 13.9 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DNA_pol_E_B PF04042.11 ETS64675.1 - 1.8e-42 144.9 0.2 2.8e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 ETS64675.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_18 PF00704.23 ETS64676.1 - 6.1e-11 42.3 1.1 8.9e-11 41.8 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Phage_CI_repr PF07022.8 ETS64676.1 - 0.068 13.2 0.0 0.079 13.0 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Zn_clus PF00172.13 ETS64677.1 - 5e-05 23.1 10.1 0.00011 22.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HbrB PF08539.6 ETS64679.1 - 4.7e-43 146.7 0.0 7.3e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 HbrB-like His_Phos_1 PF00300.17 ETS64679.1 - 5.7e-29 101.2 0.0 9.7e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ras PF00071.17 ETS64680.1 - 2.1e-20 72.7 0.0 2.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS64680.1 - 1.8e-11 44.5 0.1 6.3e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 ETS64680.1 - 0.00042 20.4 0.1 0.0015 18.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 ETS64680.1 - 0.0025 17.3 0.2 0.0047 16.4 0.1 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 ETS64680.1 - 0.0036 16.4 0.3 0.02 14.0 0.1 2.0 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 ETS64680.1 - 0.0036 16.4 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 ETS64680.1 - 0.0044 17.0 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.7 ETS64680.1 - 0.0053 16.4 0.1 0.034 13.8 0.1 2.0 2 0 0 2 2 2 1 NACHT domain Gtr1_RagA PF04670.7 ETS64680.1 - 0.011 14.8 0.0 0.013 14.6 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Arf PF00025.16 ETS64680.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family UPF0079 PF02367.12 ETS64680.1 - 0.015 14.9 0.1 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 ETS64680.1 - 0.015 14.2 0.0 0.016 14.2 0.0 1.2 1 1 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.4 ETS64680.1 - 0.021 14.3 0.2 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 ETS64680.1 - 0.025 14.1 0.2 0.27 10.7 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 ETS64680.1 - 0.038 14.8 0.1 0.063 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 ETS64680.1 - 0.047 13.6 0.2 0.077 12.9 0.2 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 ETS64680.1 - 0.051 13.8 0.1 0.088 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 ETS64680.1 - 0.069 12.7 0.2 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS64680.1 - 0.071 12.3 0.3 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 ETS64680.1 - 0.089 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 ETS64680.1 - 0.099 11.3 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit KTI12 PF08433.5 ETS64680.1 - 0.14 11.3 0.5 2 7.5 0.1 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Caleosin PF05042.8 ETS64681.1 - 2.5e-43 147.6 0.0 3.6e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Caleosin related protein Pkinase PF00069.20 ETS64682.1 - 4.9e-20 71.7 0.0 3.3e-18 65.7 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64682.1 - 2.8e-07 29.8 0.0 9.8e-07 28.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 ETS64682.1 - 0.00028 20.6 0.8 0.00053 19.7 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS64682.1 - 0.0075 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 ETS64682.1 - 0.018 14.1 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETS64682.1 - 0.055 12.8 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 RIO1 family WaaY PF06176.6 ETS64682.1 - 0.44 9.7 0.1 0.7 9.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Inositol_P PF00459.20 ETS64684.1 - 7.2e-63 212.4 0.2 8.1e-63 212.2 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family OPT PF03169.10 ETS64685.1 - 1.2e-144 483.1 17.0 1.4e-144 482.9 11.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Topoisom_bac PF01131.15 ETS64685.1 - 8.3e-90 301.4 0.0 1e-89 301.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 ETS64685.1 - 1.1e-20 73.2 11.5 3.9e-11 42.6 1.5 2.5 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.17 ETS64685.1 - 3.9e-18 65.2 0.0 1.7e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Toprim domain zf-CCHC PF00098.18 ETS64685.1 - 2e-12 46.3 15.7 1.6e-06 27.7 2.0 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 ETS64685.1 - 2e-06 27.4 7.6 0.0031 17.1 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.1 ETS64685.1 - 3.2e-05 23.3 11.5 0.0036 16.7 0.6 2.7 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 ETS64685.1 - 1.8 8.0 5.3 22 4.6 0.4 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 ETS64685.1 - 2.4 7.8 5.9 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle PhyH PF05721.8 ETS64686.1 - 2.5e-47 161.6 0.0 4e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Alpha-amylase_N PF02903.9 ETS64686.1 - 0.03 14.2 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain PALP PF00291.20 ETS64687.1 - 5.5e-28 98.0 0.0 2.6e-27 95.8 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 ETS64687.1 - 5.5e-06 26.6 0.1 0.00014 22.1 0.1 2.5 1 1 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 ETS64688.1 - 1e-54 185.3 0.2 3.5e-35 121.4 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64688.1 - 4.6e-24 84.8 0.2 1.7e-16 60.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS64688.1 - 0.0071 15.3 0.0 0.035 13.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PAP2 PF01569.16 ETS64688.1 - 0.4 10.3 3.6 0.13 11.9 0.2 1.9 2 0 0 2 2 2 0 PAP2 superfamily Glyco_hydro_31 PF01055.21 ETS64689.1 - 1.6e-158 528.1 3.8 2.1e-158 527.7 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 HAMP PF00672.20 ETS64690.1 - 3.3e-47 158.5 19.1 2e-08 34.2 0.3 8.3 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 ETS64690.1 - 1.7e-27 95.3 0.1 6.1e-27 93.5 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS64690.1 - 2e-26 92.1 0.9 2.3e-24 85.5 0.4 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 ETS64690.1 - 5.5e-17 61.5 0.3 3.9e-16 58.8 0.2 2.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 ETS64690.1 - 0.023 14.4 0.1 0.42 10.5 0.0 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Syntaxin PF00804.20 ETS64690.1 - 0.12 12.5 6.0 10 6.3 0.7 4.9 3 2 0 3 3 3 0 Syntaxin DUF2365 PF10157.4 ETS64690.1 - 0.15 11.9 10.7 45 3.8 0.1 6.4 6 2 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) SKG6 PF08693.5 ETS64691.1 - 3.9e-08 32.4 0.2 9.2e-08 31.2 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 ETS64691.1 - 0.01 14.1 0.5 0.022 13.0 0.4 1.7 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 ETS64691.1 - 0.043 13.5 0.4 0.15 11.7 0.0 2.0 1 1 1 2 2 2 0 TMEM154 protein family TMEM51 PF15345.1 ETS64691.1 - 0.86 9.2 10.5 0.025 14.2 1.9 2.2 2 1 0 2 2 2 0 Transmembrane protein 51 Yippee-Mis18 PF03226.9 ETS64692.1 - 2.8e-17 62.5 0.1 3.5e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-IS66 PF13005.2 ETS64692.1 - 0.14 12.2 3.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 GFA PF04828.9 ETS64692.1 - 0.21 11.5 1.0 0.87 9.5 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.8 ETS64692.1 - 0.31 10.5 1.8 0.96 8.9 0.1 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Sporozoite_P67 PF05642.6 ETS64692.1 - 8.3 4.1 7.3 10 3.8 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen XPA_C PF05181.7 ETS64693.1 - 1.5e-26 91.7 2.0 2.5e-26 91.0 1.4 1.4 1 0 0 1 1 1 1 XPA protein C-terminus K_channel_TID PF07941.6 ETS64693.1 - 0.014 15.5 0.8 0.014 15.5 0.6 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-ribbon_3 PF13248.1 ETS64693.1 - 0.19 10.9 1.9 16 4.8 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 ETS64693.1 - 0.29 10.8 5.4 5.6 6.7 0.1 3.3 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.2 ETS64693.1 - 0.31 10.9 3.8 14 5.6 0.0 2.7 2 1 0 2 2 2 0 Double zinc ribbon DUF1451 PF07295.6 ETS64693.1 - 2.1 8.0 6.6 2 8.1 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) Glyco_hydro_63 PF03200.11 ETS64694.1 - 2.6e-231 769.7 0.0 2e-230 766.8 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 ETS64694.1 - 3.1e-07 29.4 0.0 5.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 ETS64694.1 - 7.6e-05 21.5 0.1 0.00022 20.0 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 ETS64694.1 - 0.0031 15.7 0.0 0.0054 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase SMI1_KNR4 PF09346.5 ETS64695.1 - 3.6e-30 104.6 0.0 6.1e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) zf-met2 PF12907.2 ETS64696.1 - 9.5e-15 54.2 1.2 1.3e-14 53.8 0.9 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 ETS64696.1 - 7.5e-08 32.9 14.6 1e-07 32.5 10.1 1.2 1 0 0 1 1 1 1 4F5 protein family Rep_fac-A_C PF08646.5 ETS64696.1 - 0.04 13.6 0.1 0.041 13.6 0.1 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain Eapp_C PF10238.4 ETS64696.1 - 0.068 13.0 0.7 0.083 12.7 0.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein FAD_binding_8 PF08022.7 ETS64698.1 - 1.1e-16 60.5 0.0 7.2e-16 57.9 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 ETS64698.1 - 1.4e-13 51.0 0.0 4.4e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 ETS64698.1 - 3.6e-12 46.4 8.7 3.6e-12 46.4 6.0 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Peptidase_A22B PF04258.8 ETS64699.1 - 5.3e-72 242.7 7.0 6.5e-72 242.4 4.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 ETS64699.1 - 4.5e-07 29.2 5.1 7.3e-07 28.6 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1119) CENP-B_dimeris PF09026.5 ETS64699.1 - 0.0041 17.3 0.9 0.0041 17.3 0.6 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain PBP1_TM PF14812.1 ETS64699.1 - 0.093 13.0 0.4 0.093 13.0 0.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 ETS64699.1 - 1 8.8 6.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin CTDII PF01556.13 ETS64700.1 - 2.1e-21 75.5 1.3 2.4e-19 69.0 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 ETS64700.1 - 7.3e-21 73.6 1.9 1.3e-20 72.8 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 ETS64700.1 - 5.7e-15 55.1 19.8 9.6e-15 54.3 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 ETS64700.1 - 0.038 13.6 11.0 0.28 10.8 2.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Glyco_hydro_25 PF01183.15 ETS64701.1 - 4.2e-44 150.5 0.3 4.8e-44 150.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 SIS PF01380.17 ETS64702.1 - 1.2e-17 63.7 0.0 2.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 ETS64702.1 - 6.9e-08 32.2 0.0 0.0019 17.9 0.0 2.4 1 1 1 2 2 2 2 SIS domain CytochromB561_N PF09786.4 ETS64702.1 - 0.68 8.3 3.6 0.95 7.8 2.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MFS_1 PF07690.11 ETS64704.1 - 4.4e-41 140.7 36.2 4.4e-41 140.7 25.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.8 ETS64704.1 - 9.1 6.7 12.1 0.32 11.4 0.1 3.6 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain YTH PF04146.10 ETS64705.1 - 4.1e-46 156.0 0.0 6.2e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain PapG_N PF03627.8 ETS64705.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain ThiF PF00899.16 ETS64707.1 - 2.2e-40 137.6 0.1 3.8e-40 136.8 0.1 1.4 1 0 0 1 1 1 1 ThiF family RabGAP-TBC PF00566.13 ETS64707.1 - 3.4e-34 118.1 0.0 7.6e-33 113.7 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MoeZ_MoeB PF05237.8 ETS64707.1 - 1.5e-22 78.9 0.1 3.4e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 ETS64707.1 - 7.8e-08 32.6 0.0 2.8e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 ETS64707.1 - 3.4e-05 23.9 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ETS64707.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 ETS64707.1 - 0.064 12.2 0.3 0.12 11.3 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase LRS4 PF10422.4 ETS64707.1 - 0.33 10.2 1.8 16 4.7 0.1 2.3 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 TFIIIC_delta PF12657.2 ETS64708.1 - 9e-14 51.5 0.4 2.2e-12 47.0 0.1 2.5 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 ETS64708.1 - 0.0021 17.9 0.5 0.0049 16.7 0.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex GATase PF00117.23 ETS64709.1 - 0.00021 20.7 0.0 0.0008 18.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 ETS64709.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DnaJ-X PF14308.1 ETS64710.1 - 4.8e-58 195.7 0.8 4.8e-58 195.7 0.5 3.0 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 ETS64710.1 - 1.5e-19 69.4 0.3 1.5e-19 69.4 0.2 2.3 2 1 0 2 2 2 1 DnaJ domain FLO_LFY PF01698.11 ETS64710.1 - 0.17 10.6 10.1 0.35 9.6 7.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 ETS64710.1 - 4.2 4.9 9.2 6.4 4.3 6.4 1.2 1 0 0 1 1 1 0 Ycf1 PIF1 PF05970.9 ETS64711.1 - 7.2e-61 206.1 0.4 8.1e-49 166.4 0.1 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 ETS64711.1 - 7.4e-21 74.6 0.0 1.9e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS64711.1 - 1.9e-08 34.4 0.0 7e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS64711.1 - 1.2e-05 24.9 1.5 5.2e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 ETS64711.1 - 2.4e-05 24.4 0.0 0.0013 18.8 0.0 2.9 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 ETS64711.1 - 2.5e-05 24.3 1.0 0.00015 21.7 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 ETS64711.1 - 0.00012 21.7 0.0 0.02 14.4 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 ETS64711.1 - 0.00029 21.0 0.2 0.00085 19.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 ETS64711.1 - 0.002 17.0 0.0 0.0042 16.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 ETS64711.1 - 0.003 17.8 0.0 0.0098 16.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 ETS64711.1 - 0.0039 17.0 0.0 0.02 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 ETS64711.1 - 0.0042 15.7 0.0 0.0079 14.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 ETS64711.1 - 0.0046 15.9 0.0 0.0094 14.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 ETS64711.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 ETS64711.1 - 0.013 15.2 0.1 0.57 9.8 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_32 PF13654.1 ETS64711.1 - 0.014 14.1 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETS64711.1 - 0.015 14.5 0.0 0.048 12.8 0.0 1.8 2 0 0 2 2 1 0 PhoH-like protein Herpes_Helicase PF02689.9 ETS64711.1 - 0.017 12.8 0.1 0.13 10.0 0.0 2.0 2 0 0 2 2 2 0 Helicase Mg_chelatase PF01078.16 ETS64711.1 - 0.02 14.0 0.0 0.047 12.8 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETS64711.1 - 0.02 14.3 0.1 0.078 12.4 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 ETS64711.1 - 0.02 14.5 0.3 0.35 10.5 0.2 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS64711.1 - 0.025 14.7 0.0 0.069 13.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 ETS64711.1 - 0.032 13.9 0.2 0.095 12.3 0.1 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 ETS64711.1 - 0.044 13.3 2.1 0.36 10.3 0.0 2.8 2 1 0 3 3 3 0 AAA domain MobB PF03205.9 ETS64711.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 ETS64711.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 ETS64711.1 - 0.072 12.4 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 ETS64711.1 - 0.094 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NB-ARC PF00931.17 ETS64711.1 - 0.096 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 ETS64711.1 - 0.1 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Phage_tail PF04630.7 ETS64711.1 - 0.15 11.1 0.2 0.29 10.1 0.1 1.4 1 0 0 1 1 1 0 Phage major tail protein Cys_Met_Meta_PP PF01053.15 ETS64712.1 - 2.8e-55 187.2 0.2 1.3e-46 158.6 0.1 2.7 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETS64712.1 - 0.0028 16.6 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.21 ETS64713.1 - 0.15 12.5 0.8 0.33 11.3 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2420 PF10336.4 ETS64716.1 - 1.6e-26 92.1 0.0 3e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Thiolase_N PF00108.18 ETS64717.1 - 1.2e-79 266.9 5.0 1.7e-79 266.5 3.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS64717.1 - 1.9e-42 143.5 0.7 1.9e-42 143.5 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 ETS64717.1 - 0.0037 17.2 0.1 0.014 15.3 0.1 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 ETS64717.1 - 0.047 13.1 0.3 0.047 13.1 0.2 2.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Myosin_N PF02736.14 ETS64717.1 - 0.52 10.0 2.6 0.52 10.0 0.7 1.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Histone PF00125.19 ETS64718.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETS64718.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 ETS64718.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 ETS64718.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 ETS64718.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Reprolysin_5 PF13688.1 ETS64719.1 - 2.9e-43 148.1 9.1 2.9e-43 148.1 6.3 2.8 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 ETS64719.1 - 2.5e-36 125.3 10.1 2.5e-36 125.3 7.0 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 ETS64719.1 - 2.1e-35 122.1 2.0 4.4e-35 121.0 1.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ETS64719.1 - 7e-19 68.5 1.9 1.4e-18 67.6 0.2 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 ETS64719.1 - 1.9e-14 53.6 25.6 1.9e-14 53.6 17.7 4.6 2 1 2 4 4 4 1 Disintegrin Reprolysin PF01421.14 ETS64719.1 - 1e-09 38.2 8.6 1.3e-07 31.4 5.9 2.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 ETS64719.1 - 4e-08 33.1 0.3 6.7e-08 32.3 0.2 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M43 PF05572.8 ETS64719.1 - 0.011 15.3 0.2 0.03 13.9 0.1 1.8 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.4 ETS64719.1 - 0.06 12.2 0.7 0.099 11.4 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 PgaD PF13994.1 ETS64719.1 - 0.17 11.3 0.1 0.37 10.2 0.1 1.5 1 0 0 1 1 1 0 PgaD-like protein Cyclin PF08613.6 ETS64720.1 - 3.6e-36 124.8 0.1 1.5e-21 77.3 0.0 3.1 2 0 0 2 2 2 2 Cyclin EFG_C PF00679.19 ETS64720.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G C-terminus HMG_box PF00505.14 ETS64722.1 - 9.2e-13 48.2 2.4 1.6e-12 47.5 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS64722.1 - 0.00019 21.7 0.2 0.00042 20.6 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain DHC PF09626.5 ETS64722.1 - 0.00085 19.9 0.9 0.16 12.6 0.0 2.5 2 0 0 2 2 2 2 Dihaem cytochrome c Ribosomal_S4e PF00900.15 ETS64723.1 - 4e-31 106.5 0.2 9.9e-31 105.2 0.2 1.7 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 ETS64723.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 ETS64723.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 ETS64723.1 - 0.00017 21.1 2.2 0.00017 21.1 1.5 2.3 2 0 0 2 2 2 1 KOW motif MFS_1 PF07690.11 ETS64724.1 - 1.2e-09 37.3 23.7 1.2e-09 37.3 16.4 3.9 4 1 0 4 4 4 2 Major Facilitator Superfamily PAH PF02671.16 ETS64725.1 - 4.9e-44 147.7 3.1 7.4e-18 63.9 0.8 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 ETS64725.1 - 1.6e-39 133.7 0.6 5.5e-39 132.0 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Ribosomal_S21e PF01249.13 ETS64726.1 - 1.2e-32 111.7 0.0 2.2e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S21e MFS_1 PF07690.11 ETS64727.1 - 1.8e-30 105.8 26.5 1.8e-30 105.8 18.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Selenoprotein_S PF06936.6 ETS64727.1 - 0.032 13.7 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Selenoprotein S (SelS) Phi-29_GP16_7 PF06720.6 ETS64727.1 - 0.045 13.4 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 MARVEL PF01284.18 ETS64728.1 - 0.00031 20.5 19.5 0.015 15.0 4.2 3.2 2 1 1 3 3 3 3 Membrane-associating domain DUF2189 PF09955.4 ETS64728.1 - 2.7 7.9 19.9 3 7.8 0.7 3.1 2 1 0 3 3 3 0 Predicted integral membrane protein (DUF2189) DUF4064 PF13273.1 ETS64728.1 - 9.5 6.3 13.7 2.3 8.3 0.2 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF4064) Cytochrom_C PF00034.16 ETS64729.1 - 1.5e-09 38.5 0.0 2.3e-09 37.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 ETS64729.1 - 1.1e-08 35.0 2.2 7.2e-08 32.4 1.5 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 ETS64729.1 - 7.8e-05 22.1 0.9 0.00045 19.6 0.1 2.1 2 1 0 2 2 2 1 Cytochrome c-550 domain Peptidase_M13_N PF05649.8 ETS64730.1 - 2.2e-95 320.0 0.0 2.8e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 ETS64730.1 - 9.7e-57 191.4 0.0 1.4e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_MA_2 PF13485.1 ETS64730.1 - 0.037 14.0 0.3 0.074 13.0 0.2 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily SRP54 PF00448.17 ETS64732.1 - 2.2e-76 255.6 0.2 4.2e-76 254.7 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 ETS64732.1 - 3.5e-21 75.4 0.1 3.5e-21 75.4 0.1 4.8 3 2 2 5 5 5 1 Signal peptide binding domain SRP54_N PF02881.14 ETS64732.1 - 8.2e-12 45.0 0.1 2.3e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 ETS64732.1 - 3.2e-06 27.0 0.0 8.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 ETS64732.1 - 4e-06 26.4 0.1 1.3e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 ETS64732.1 - 0.00042 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 ETS64732.1 - 0.0016 18.5 0.2 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_31 PF13614.1 ETS64732.1 - 0.0029 17.5 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS64732.1 - 0.0032 17.6 0.5 0.016 15.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain CbiA PF01656.18 ETS64732.1 - 0.0038 16.6 0.1 0.016 14.6 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 ETS64732.1 - 0.0089 16.8 0.0 0.018 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 ETS64732.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase GTP_EFTU PF00009.22 ETS64732.1 - 0.058 12.8 0.1 0.19 11.1 0.1 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 ETS64732.1 - 0.067 13.5 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 ETS64732.1 - 0.068 11.7 0.9 1.4 7.5 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain 6PF2K PF01591.13 ETS64732.1 - 0.092 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 ETS64732.1 - 0.1 12.1 0.7 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Vps55 PF04133.9 ETS64733.1 - 1.3e-46 157.2 4.1 1.4e-46 157.0 2.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2040 PF09745.4 ETS64734.1 - 1.2e-35 122.0 20.2 1.2e-35 122.0 14.0 2.8 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Rot1 PF10681.4 ETS64735.1 - 2.8e-57 193.5 2.3 3.4e-57 193.2 1.6 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VanZ PF04892.7 ETS64736.1 - 5.6e-10 39.2 0.3 1.2e-09 38.1 0.2 1.5 1 1 0 1 1 1 1 VanZ like family Cyclin_N PF00134.18 ETS64738.1 - 1.9e-13 50.0 0.0 4.3e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 ETS64738.1 - 1.1e-11 45.3 0.2 2.2e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Cyclin CDC45 PF02724.9 ETS64738.1 - 0.0073 14.4 6.4 0.0098 13.9 4.4 1.1 1 0 0 1 1 1 1 CDC45-like protein BTB PF00651.26 ETS64740.1 - 0.034 14.1 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain CwfJ_C_1 PF04677.10 ETS64741.1 - 5.7e-25 87.3 0.0 8.8e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 ETS64741.1 - 5.2e-09 36.4 0.3 3.2e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 2 Aconitase PF00330.15 ETS64742.1 - 1.4e-155 518.2 0.0 3.3e-155 517.1 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS64742.1 - 1.6e-33 115.5 0.0 3.1e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 ETS64742.1 - 1.6e-06 28.0 1.5 0.00014 21.6 0.3 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 RdRP PF05183.7 ETS64743.1 - 5.6e-111 372.0 0.0 7.9e-111 371.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase SAP PF02037.22 ETS64744.1 - 8.3e-05 21.9 0.2 0.00017 21.0 0.2 1.5 1 0 0 1 1 1 1 SAP domain Polysacc_deac_1 PF01522.16 ETS64745.1 - 1.7e-28 98.7 0.0 3.7e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Serglycin PF04360.7 ETS64745.1 - 0.0016 18.2 1.9 0.0044 16.7 1.3 1.7 1 1 0 1 1 1 1 Serglycin Macoilin PF09726.4 ETS64745.1 - 0.39 8.9 7.7 0.5 8.5 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Ran_BP1 PF00638.13 ETS64749.1 - 2.7e-17 62.9 0.9 5.3e-17 61.9 0.6 1.5 1 0 0 1 1 1 1 RanBP1 domain HAT PF02184.11 ETS64750.1 - 5.7e-17 61.1 58.6 6.7e-09 35.3 0.0 14.0 14 1 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 ETS64750.1 - 2.8e-14 52.3 42.2 0.00092 19.6 0.0 12.9 9 2 6 15 15 14 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS64750.1 - 9.9e-13 48.2 8.1 0.0054 17.0 0.1 7.8 5 1 4 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETS64750.1 - 2.6e-12 45.6 8.2 0.023 14.6 0.1 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS64750.1 - 6.6e-09 36.1 25.8 0.00023 21.7 0.0 8.0 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS64750.1 - 5e-08 32.4 8.8 0.02 14.5 0.0 7.0 5 2 3 8 8 8 1 TPR repeat TPR_8 PF13181.1 ETS64750.1 - 1.6e-07 30.5 3.0 0.02 14.6 0.0 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS64750.1 - 2e-07 30.3 0.6 0.51 10.0 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS64750.1 - 6.2e-07 29.1 0.0 0.0034 17.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 ETS64750.1 - 1.5e-05 24.6 15.5 0.12 12.1 0.0 6.8 5 2 3 8 8 8 2 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.1 ETS64750.1 - 8.6e-05 22.3 2.8 0.24 11.2 0.0 4.5 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 ETS64750.1 - 0.00015 21.6 20.9 0.64 9.9 0.4 8.0 6 3 0 6 6 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 ETS64750.1 - 0.0042 16.8 2.7 0.0042 16.8 1.9 5.2 5 2 1 6 6 5 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 ETS64750.1 - 0.098 12.4 29.5 1.7 8.5 0.0 10.1 12 0 0 12 12 11 0 Tetratricopeptide repeat Nbl1_Borealin_N PF10444.4 ETS64750.1 - 0.25 10.7 0.1 0.25 10.7 0.0 2.7 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal TPR_6 PF13174.1 ETS64750.1 - 5.2 7.7 25.8 11 6.7 0.0 9.4 11 1 0 11 11 8 0 Tetratricopeptide repeat SET PF00856.23 ETS64751.1 - 7.6e-26 91.3 0.0 7.6e-26 91.3 0.0 3.4 3 1 0 3 3 3 1 SET domain N-SET PF11764.3 ETS64751.1 - 1.4e-17 64.1 0.0 1.4e-17 64.1 0.0 3.5 3 1 1 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 ETS64751.1 - 3.8e-06 26.1 0.0 6.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated LSM PF01423.17 ETS64752.1 - 4.6e-16 58.1 0.1 5.8e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Arf PF00025.16 ETS64753.1 - 2e-71 238.8 0.0 2.6e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETS64753.1 - 6.1e-12 45.2 0.0 8.7e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 ETS64753.1 - 5.1e-11 41.8 0.4 9.8e-07 27.7 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 ETS64753.1 - 1.5e-10 40.6 0.0 2.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETS64753.1 - 9.8e-10 37.9 0.0 1.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS64753.1 - 3.3e-06 27.5 0.0 4.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS64753.1 - 0.00023 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETS64754.1 - 1e-33 116.5 0.0 2.2e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 ETS64754.1 - 1.8e-23 83.3 14.6 1.8e-23 83.3 9.2 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 ETS64754.1 - 5.6e-06 26.5 0.0 0.0096 15.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 ETS64754.1 - 2.6e-05 23.5 0.1 0.0014 17.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS64754.1 - 8.1e-05 22.6 0.4 8.1e-05 22.6 0.3 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS64754.1 - 0.0017 18.4 0.1 0.013 15.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 ETS64754.1 - 0.0018 17.4 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 ETS64754.1 - 0.0062 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 ETS64754.1 - 0.0076 15.7 0.1 0.023 14.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 ETS64754.1 - 0.033 14.3 0.0 0.31 11.2 0.0 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETS64754.1 - 0.038 13.3 0.1 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Troponin-I_N PF11636.3 ETS64754.1 - 5.5 6.7 8.8 0.27 10.9 1.5 2.3 2 0 0 2 2 2 0 Troponin I residues 1-32 DUF2408 PF10303.4 ETS64755.1 - 5.5e-55 185.1 0.5 2.3e-38 131.3 0.0 4.5 3 1 1 4 4 4 4 Protein of unknown function (DUF2408) DUF972 PF06156.8 ETS64755.1 - 0.0052 17.1 0.1 0.14 12.5 0.0 3.1 4 1 0 4 4 4 1 Protein of unknown function (DUF972) DUF724 PF05266.9 ETS64755.1 - 0.14 11.7 1.5 0.23 11.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Nop14 PF04147.7 ETS64755.1 - 0.62 7.9 4.5 1.6 6.5 3.1 1.7 1 0 0 1 1 1 0 Nop14-like family Copper-fist PF00649.13 ETS64757.1 - 8.7e-13 47.2 1.8 8.7e-13 47.2 1.3 2.3 2 0 0 2 2 2 1 Copper fist DNA binding domain RED_N PF07808.8 ETS64758.1 - 3e-10 39.7 1.1 5.1e-10 38.9 0.8 1.4 1 0 0 1 1 1 1 RED-like protein N-terminal region AvrE PF11725.3 ETS64758.1 - 8.1 3.3 13.9 1.3 5.9 7.3 1.3 1 1 0 1 1 1 0 Pathogenicity factor Phos_pyr_kin PF08543.7 ETS64759.1 - 9e-11 41.4 0.0 1.4e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 ETS64759.1 - 3.3e-09 36.3 0.0 3.5e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DUF1690 PF07956.6 ETS64760.1 - 1.4e-14 54.2 5.5 2.7e-14 53.3 3.8 1.5 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) STAT_int PF02865.12 ETS64760.1 - 0.033 14.1 0.4 0.54 10.2 0.0 2.2 1 1 0 2 2 2 0 STAT protein, protein interaction domain T2SG PF08334.6 ETS64760.1 - 0.045 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Mnd1 PF03962.10 ETS64760.1 - 0.066 12.8 5.3 0.096 12.3 3.7 1.4 1 0 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 ETS64760.1 - 0.077 13.0 4.9 0.17 11.9 3.4 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4510 PF14971.1 ETS64760.1 - 0.65 10.1 5.5 0.3 11.2 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) IncA PF04156.9 ETS64760.1 - 2.3 7.7 5.7 3.7 7.1 4.0 1.4 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 ETS64760.1 - 8.1 6.2 7.4 4.8 6.9 0.8 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper CENP-N PF05238.8 ETS64761.1 - 2e-70 237.8 0.0 2.5e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like ArgJ PF01960.13 ETS64762.1 - 2.6e-132 440.8 0.1 2.9e-132 440.7 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Thioredoxin_8 PF13905.1 ETS64763.1 - 1e-09 38.3 0.0 4.3e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Aminotran_1_2 PF00155.16 ETS64764.1 - 1.3e-30 106.5 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aldo_ket_red PF00248.16 ETS64765.1 - 2.3e-34 118.5 0.0 6e-34 117.1 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family DUF21 PF01595.15 ETS64766.1 - 3.5e-34 117.6 0.6 6.2e-34 116.8 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 ETS64766.1 - 3.6e-06 26.6 0.3 0.28 11.0 0.0 3.6 3 0 0 3 3 3 3 CBS domain HIT PF01230.18 ETS64767.1 - 1.4e-11 44.7 1.9 1.8e-05 25.1 0.5 2.4 2 0 0 2 2 2 2 HIT domain DcpS_C PF11969.3 ETS64767.1 - 1.4e-11 44.6 2.9 4.2e-11 43.0 2.0 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1_like PF12832.2 ETS64768.1 - 8.7e-21 73.5 0.1 8.7e-21 73.5 0.1 2.5 2 0 0 2 2 2 1 MFS_1 like family CoA_trans PF01144.18 ETS64769.1 - 4.3e-108 359.4 1.5 1.2e-63 214.1 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 ETS64769.1 - 0.00047 19.8 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DeoRC PF00455.17 ETS64769.1 - 0.025 14.2 0.0 0.7 9.5 0.0 2.7 3 0 0 3 3 3 0 DeoR C terminal sensor domain SUI1 PF01253.17 ETS64770.1 - 1.4e-29 101.7 3.2 2.2e-29 101.0 2.2 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 GATA PF00320.22 ETS64771.1 - 1.2e-13 50.1 3.4 2.8e-13 48.9 2.3 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 ETS64771.1 - 1.1e-08 35.0 0.0 2e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 ETS64771.1 - 1.4e-08 34.9 0.3 1.7e-07 31.5 0.0 2.8 3 1 0 3 3 3 1 PAS domain PAS PF00989.19 ETS64771.1 - 2.4e-08 33.7 0.1 2.1e-07 30.6 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.5 ETS64771.1 - 2.2e-06 27.6 0.0 6.8e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 ETS64771.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.7 ETS64771.1 - 0.14 11.4 0.3 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding UBX PF00789.15 ETS64772.1 - 1e-11 44.7 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 ETS64772.1 - 0.008 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OmpH PF03938.9 ETS64772.1 - 0.12 12.2 4.5 0.19 11.6 3.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDHD PF02862.12 ETS64772.1 - 0.15 11.8 1.5 0.25 11.0 1.0 1.3 1 0 0 1 1 1 0 DDHD domain ARGLU PF15346.1 ETS64772.1 - 0.29 10.8 27.6 0.57 9.9 19.1 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 WD40 PF00400.27 ETS64773.1 - 3.4e-43 144.0 21.6 7.6e-10 38.2 0.1 11.3 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 ETS64773.1 - 4.5e-16 58.7 0.0 7.5e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 ETS64773.1 - 0.00034 18.9 0.1 0.96 7.4 0.0 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETS64773.1 - 0.0051 15.1 0.0 3.1 5.9 0.0 3.2 3 0 0 3 3 3 2 Cytochrome D1 heme domain DUF1513 PF07433.6 ETS64773.1 - 0.064 12.1 0.2 2.5 6.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) YjeF_N PF03853.10 ETS64774.1 - 3.6e-33 114.5 0.0 4.5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus RabGAP-TBC PF00566.13 ETS64775.1 - 5.1e-32 111.0 0.5 1e-31 110.0 0.3 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 ETS64775.1 - 2.3e-05 23.8 0.0 0.00084 18.6 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) VGLL4 PF15245.1 ETS64775.1 - 1.7 8.4 6.3 0.61 9.8 2.0 1.9 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 PQQ_3 PF13570.1 ETS64776.1 - 0.002 18.3 5.2 0.017 15.3 0.1 4.1 4 0 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.1 ETS64776.1 - 0.0054 16.2 1.9 0.034 13.6 0.1 2.3 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 ETS64776.1 - 2 8.1 4.6 2.4 7.8 0.2 3.2 3 1 1 4 4 4 0 PQQ enzyme repeat PBP1_TM PF14812.1 ETS64776.1 - 4.7 7.5 11.3 0.38 11.0 3.9 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NMT PF01233.14 ETS64777.1 - 2e-76 255.1 0.0 3.1e-76 254.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 ETS64777.1 - 6.1e-64 214.9 0.0 1.4e-62 210.4 0.0 2.5 2 1 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 ETS64777.1 - 0.00018 21.3 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS64777.1 - 0.02 14.9 0.0 0.67 10.0 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS64777.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PBP1_TM PF14812.1 ETS64777.1 - 0.063 13.5 10.6 0.15 12.4 7.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3258 PF11646.3 ETS64777.1 - 0.12 12.5 0.1 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF3258 Nucleoplasmin PF03066.10 ETS64777.1 - 0.26 10.8 10.9 0.49 9.9 7.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop53 PF07767.6 ETS64777.1 - 0.43 9.5 16.9 0.34 9.8 5.9 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) TraF PF13728.1 ETS64777.1 - 0.67 9.3 6.8 1.7 8.0 4.4 1.8 1 1 1 2 2 2 0 F plasmid transfer operon protein NOA36 PF06524.7 ETS64777.1 - 0.78 8.9 10.8 1.2 8.3 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.8 ETS64777.1 - 2.1 5.9 9.5 3.4 5.3 6.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.5 ETS64777.1 - 2.6 8.3 12.2 7 6.9 8.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_RNA_Pol_19 PF05320.7 ETS64777.1 - 3 7.5 7.1 8 6.1 4.9 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PGA2 PF07543.7 ETS64777.1 - 3.8 7.3 12.6 0.14 11.9 4.4 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 CDC45 PF02724.9 ETS64777.1 - 6.2 4.7 11.9 11 3.8 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 ETS64777.1 - 8.4 6.0 7.0 19 4.9 4.9 1.6 1 0 0 1 1 1 0 FAM176 family G-patch PF01585.18 ETS64778.1 - 1.3e-10 40.8 6.2 2.5e-10 39.9 4.0 1.7 1 1 1 2 2 2 2 G-patch domain G-patch_2 PF12656.2 ETS64778.1 - 1.5e-06 27.9 0.4 3.1e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-C2H2_jaz PF12171.3 ETS64778.1 - 0.011 15.8 0.7 0.019 15.1 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 ETS64778.1 - 0.06 13.4 0.3 0.095 12.8 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 ETS64778.1 - 0.079 13.3 0.8 0.15 12.4 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS64778.1 - 0.097 13.0 0.3 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger SAM_2 PF07647.12 ETS64779.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FA_desaturase PF00487.19 ETS64781.1 - 1.4e-28 100.0 18.1 2.7e-28 99.1 12.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 ETS64781.1 - 1.7e-19 68.7 0.9 3e-19 67.9 0.7 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) WD40 PF00400.27 ETS64782.1 - 3.2e-18 64.8 6.2 3.5e-05 23.5 1.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2407_C PF13373.1 ETS64783.1 - 2.8e-13 50.0 12.7 8.2e-12 45.2 0.9 3.9 3 1 0 3 3 3 2 DUF2407 C-terminal domain DUF2407 PF10302.4 ETS64783.1 - 7e-11 42.1 0.0 8.6e-10 38.6 0.0 2.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 ETS64783.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family PBP1_TM PF14812.1 ETS64783.1 - 2.3 8.5 5.6 1.9 8.8 2.3 2.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ChaC PF04752.7 ETS64784.1 - 3.1e-50 170.5 0.0 5.8e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 ETS64784.1 - 1.9e-25 88.3 3.6 4.8e-25 87.0 2.5 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 ETS64784.1 - 3.8e-10 39.6 3.5 2.1e-08 34.0 0.5 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS64784.1 - 2.7e-07 30.5 4.3 2.7e-06 27.4 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETS64784.1 - 2.3e-06 27.6 0.1 0.01 15.8 0.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Staphylokinase PF02821.11 ETS64784.1 - 0.00092 18.9 0.2 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Staphylokinase/Streptokinase family zf-C2H2 PF00096.21 ETS64784.1 - 0.0086 16.3 3.1 0.57 10.6 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS64784.1 - 0.049 13.9 2.6 1.9 9.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger LUC7 PF03194.10 ETS64785.1 - 2.8e-72 243.2 2.2 2.8e-72 243.2 1.5 1.8 2 0 0 2 2 2 1 LUC7 N_terminus DIM1 PF02966.11 ETS64785.1 - 2.2e-64 214.9 0.1 3.5e-64 214.2 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 Nitroreductase PF00881.19 ETS64786.1 - 1.6e-09 37.7 0.0 2.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family COX6B PF02297.12 ETS64787.1 - 5.4e-17 61.5 5.3 5.9e-17 61.4 1.7 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 ETS64787.1 - 0.055 12.8 1.3 0.11 11.9 0.9 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UCR_hinge PF02320.11 ETS64787.1 - 0.077 12.9 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 ETS64787.1 - 0.087 12.7 0.7 0.21 11.5 0.5 1.7 1 1 0 1 1 1 0 CHCH domain mRNA_stabil PF13929.1 ETS64787.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 mRNA stabilisation Prp18 PF02840.10 ETS64788.1 - 1.6e-57 193.3 0.0 3.1e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 ETS64788.1 - 1.5e-11 43.3 5.0 1.5e-11 43.3 3.5 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like BNIP3 PF06553.7 ETS64788.1 - 0.094 12.0 6.8 0.17 11.2 4.7 1.5 1 0 0 1 1 1 0 BNIP3 Hamartin PF04388.7 ETS64788.1 - 0.22 10.1 4.8 0.28 9.7 3.3 1.1 1 0 0 1 1 1 0 Hamartin protein Pex2_Pex12 PF04757.9 ETS64789.1 - 7.9e-40 136.6 2.5 1.1e-39 136.2 1.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 ETS64789.1 - 4.5e-09 35.9 8.9 6.9e-09 35.4 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS64789.1 - 2e-06 27.8 4.6 3.2e-06 27.1 3.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETS64789.1 - 1.3e-05 24.7 5.6 2.1e-05 24.0 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS64789.1 - 0.00027 20.8 7.8 0.00042 20.2 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS64789.1 - 0.00084 19.0 6.4 0.0013 18.4 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS64789.1 - 0.00094 18.7 7.7 0.0015 18.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS64789.1 - 0.0014 18.3 3.9 0.0025 17.6 2.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 ETS64789.1 - 0.074 12.2 0.1 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 ETS64789.1 - 0.12 11.9 2.4 0.21 11.1 1.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 ETS64789.1 - 3.5 7.5 7.4 1.4 8.8 2.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING USP7_ICP0_bdg PF12436.3 ETS64790.1 - 5.9e-85 284.4 2.3 9.2e-85 283.8 1.1 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 ETS64790.1 - 6e-65 218.6 2.5 4.2e-64 215.8 0.8 2.4 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 ETS64790.1 - 3.8e-58 196.7 0.0 6.1e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS64790.1 - 1.5e-31 109.9 0.0 2.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 ETS64790.1 - 1e-08 35.4 0.4 3.7e-07 30.4 0.0 3.6 3 2 1 4 4 4 1 MATH domain SDP_N PF12278.3 ETS64790.1 - 0.034 13.7 0.8 0.065 12.8 0.5 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Rad60-SLD PF11976.3 ETS64790.1 - 0.037 13.6 0.3 1.2 8.8 0.0 3.4 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Miro PF08477.8 ETS64793.1 - 5.2e-39 133.4 0.0 1.1e-19 71.0 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 ETS64793.1 - 3.3e-35 119.2 0.1 1.8e-34 116.8 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 ETS64793.1 - 6.4e-31 106.9 0.0 5.2e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.7 ETS64793.1 - 1.2e-27 95.4 0.0 5.8e-27 93.2 0.0 2.0 2 0 0 2 2 2 1 EF hand associated MMR_HSR1 PF01926.18 ETS64793.1 - 4.5e-09 36.2 0.0 3.4e-06 26.9 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.1 ETS64793.1 - 4.7e-09 36.2 0.5 0.0041 17.2 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETS64793.1 - 2.5e-08 32.6 2.0 0.006 15.8 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETS64793.1 - 5e-07 29.0 3.6 0.0063 16.3 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 ETS64793.1 - 6.6e-06 25.2 4.9 0.037 13.3 0.2 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.16 ETS64793.1 - 1.1e-05 24.7 0.0 0.049 12.8 0.0 3.1 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 ETS64793.1 - 9.7e-05 22.5 0.0 0.8 9.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain SRPRB PF09439.5 ETS64793.1 - 0.00025 20.3 0.0 0.67 9.1 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit MobB PF03205.9 ETS64793.1 - 0.00029 20.5 0.2 0.08 12.6 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_8 PF13833.1 ETS64793.1 - 0.00035 20.1 1.9 0.074 12.6 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair GTP_EFTU PF00009.22 ETS64793.1 - 0.0005 19.5 0.0 0.87 8.9 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 ETS64793.1 - 0.0012 18.3 0.0 0.082 12.3 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 ETS64793.1 - 0.002 18.3 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 ETS64793.1 - 0.0033 17.2 0.1 2.2 8.1 0.0 2.5 2 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 ETS64793.1 - 0.0035 17.3 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 ETS64793.1 - 0.0049 16.5 0.0 0.49 10.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETS64793.1 - 0.0081 16.1 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 ETS64793.1 - 0.012 15.1 0.6 5.4 6.4 0.0 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 ETS64793.1 - 0.013 14.8 0.0 0.63 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS64793.1 - 0.014 15.1 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 ETS64793.1 - 0.015 14.7 0.0 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 ETS64793.1 - 0.02 14.3 0.3 1.6 8.1 0.1 2.5 2 1 1 3 3 2 0 FtsK/SpoIIIE family NOG1 PF06858.9 ETS64793.1 - 0.026 14.3 0.1 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_19 PF13245.1 ETS64793.1 - 0.03 14.0 3.2 0.23 11.2 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain AAA_29 PF13555.1 ETS64793.1 - 0.041 13.4 0.1 3.2 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 ETS64793.1 - 0.045 12.9 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 EF-hand_10 PF14788.1 ETS64793.1 - 0.054 13.1 2.8 0.16 11.6 0.2 2.3 2 0 0 2 2 2 0 EF hand cobW PF02492.14 ETS64793.1 - 0.058 12.8 0.9 2 7.8 0.1 3.1 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 ETS64793.1 - 0.066 12.4 0.1 0.37 10.0 0.0 2.2 3 0 0 3 3 3 0 Ferrous iron transport protein B RNA_helicase PF00910.17 ETS64793.1 - 0.069 13.3 0.0 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 ETS64793.1 - 0.073 13.2 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS64793.1 - 0.081 12.3 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DAP3 PF10236.4 ETS64793.1 - 0.087 11.7 0.1 0.24 10.2 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 ETS64793.1 - 0.097 12.2 0.0 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS64793.1 - 0.1 12.8 0.0 20 5.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter VirE PF05272.6 ETS64793.1 - 0.13 11.6 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E NTPase_1 PF03266.10 ETS64793.1 - 0.14 11.8 0.5 0.77 9.4 0.0 2.3 2 1 1 3 3 3 0 NTPase AAA_14 PF13173.1 ETS64793.1 - 0.15 11.9 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rnk_N PF14760.1 ETS64793.1 - 0.18 11.9 0.6 0.59 10.2 0.0 2.1 2 0 0 2 2 1 0 Rnk N-terminus DUF2075 PF09848.4 ETS64793.1 - 0.2 10.6 0.2 0.78 8.6 0.0 1.9 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2075) SPARC_Ca_bdg PF10591.4 ETS64793.1 - 0.25 11.3 0.6 12 5.9 0.0 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region G-alpha PF00503.15 ETS64793.1 - 0.28 9.8 0.1 4.1 5.9 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit Septin PF00735.13 ETS64793.1 - 0.3 10.0 0.0 3.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Septin NAD_binding_4 PF07993.7 ETS64794.1 - 3.7e-32 111.2 0.0 6.4e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS64794.1 - 5.3e-28 97.5 0.1 8e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 ETS64794.1 - 1.1e-05 25.5 0.0 4e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1885 PF08968.5 ETS64794.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) 3Beta_HSD PF01073.14 ETS64794.1 - 0.31 9.6 0.0 0.51 8.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aminotran_5 PF00266.14 ETS64796.1 - 3.3e-31 108.3 0.0 4.8e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 ETS64796.1 - 0.011 15.6 0.0 0.034 14.0 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain HAD_2 PF13419.1 ETS64797.1 - 9.3e-18 65.0 2.9 2.1e-17 63.9 2.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS64797.1 - 1e-07 31.5 0.0 2.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like zf-C3HC4_2 PF13923.1 ETS64798.1 - 7.4e-10 38.7 7.0 1.2e-09 37.9 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS64798.1 - 4.2e-09 35.9 3.1 1.1e-08 34.5 2.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS64798.1 - 7e-08 32.1 6.5 1.1e-07 31.5 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS64798.1 - 2.1e-06 27.2 3.1 3.5e-06 26.5 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS64798.1 - 5.7e-06 25.9 3.9 1.1e-05 25.0 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETS64798.1 - 0.0001 22.0 4.2 0.0001 22.0 2.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS64798.1 - 0.00057 19.5 2.4 0.00057 19.5 1.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger FYVE PF01363.16 ETS64798.1 - 0.065 13.1 0.5 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 ETS64798.1 - 0.38 10.3 4.2 0.73 9.3 2.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Gly_transf_sug PF04488.10 ETS64799.1 - 2e-05 24.9 0.1 4.6e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SSF PF00474.12 ETS64800.1 - 1.7e-18 66.4 20.4 1.7e-18 66.4 14.1 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family DUF912 PF06024.7 ETS64800.1 - 4.4 7.4 0.0 4.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pyr_redox_3 PF13738.1 ETS64801.1 - 7.3e-10 39.2 0.3 4.7e-05 23.5 0.1 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS64801.1 - 4.6e-08 32.3 0.0 6.2e-05 22.0 0.0 2.7 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS64801.1 - 2.4e-06 27.5 0.0 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS64801.1 - 3.9e-05 22.7 0.1 3.9e-05 22.7 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS64801.1 - 5e-05 23.1 2.0 0.28 10.9 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS64801.1 - 0.00042 19.4 0.3 0.0013 17.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS64801.1 - 0.0037 16.2 0.2 2.6 6.8 0.0 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 ETS64801.1 - 0.098 11.1 0.1 1.2 7.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein RNA_pol_Rpb1_5 PF04998.12 ETS64803.1 - 2.2e-88 296.1 0.1 4e-88 295.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 ETS64803.1 - 3.3e-47 160.5 0.0 8.1e-47 159.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 ETS64803.1 - 2.7e-37 127.9 0.0 5.3e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 ETS64803.1 - 1.2e-25 90.4 8.6 1.7e-21 76.8 0.0 4.6 6 1 0 6 6 6 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 ETS64803.1 - 1.6e-23 82.4 0.0 8.2e-23 80.2 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Bac_rhodopsin PF01036.13 ETS64804.1 - 7.1e-06 25.4 0.0 9.6e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3452 PF11934.3 ETS64805.1 - 0.031 13.5 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) NUDIX PF00293.23 ETS64806.1 - 2.4e-09 36.9 0.0 7e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Nipped-B_C PF12830.2 ETS64806.1 - 0.024 14.2 0.5 0.27 10.8 0.0 2.6 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Adaptin_N PF01602.15 ETS64806.1 - 0.034 12.4 0.2 0.41 8.9 0.1 2.4 2 0 0 2 2 2 0 Adaptin N terminal region Ala_racemase_N PF01168.15 ETS64807.1 - 4.1e-32 111.5 0.8 6.1e-31 107.6 0.2 2.7 2 1 0 2 2 2 1 Alanine racemase, N-terminal domain MCM_bind PF09739.4 ETS64807.1 - 9.8e-23 80.0 0.0 2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 ETS64807.1 - 6.4e-18 64.8 0.0 1.4e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Putative alanine racemase CS PF04969.11 ETS64808.1 - 6.7e-20 71.4 0.2 1.1e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 CS domain Metal_resist PF13801.1 ETS64808.1 - 0.0022 17.9 2.9 0.37 10.7 0.0 2.1 2 0 0 2 2 2 2 Heavy-metal resistance 6PF2K PF01591.13 ETS64809.1 - 2.8e-71 239.1 0.0 4.4e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 ETS64809.1 - 1.3e-30 106.5 0.0 1.4e-29 103.2 0.0 2.3 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 ETS64809.1 - 1.8e-09 37.6 0.0 4.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS64809.1 - 0.0029 18.4 0.2 0.021 15.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 ETS64809.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 ETS64809.1 - 0.015 14.5 0.1 0.063 12.4 0.0 2.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Zip PF02535.17 ETS64809.1 - 0.088 11.7 3.7 0.12 11.3 2.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RCC1 PF00415.13 ETS64810.1 - 5.5e-20 71.3 0.1 0.00056 20.0 0.0 5.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 ETS64810.1 - 2.5e-17 62.8 0.0 3.7e-08 33.3 0.0 3.5 2 1 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.1 ETS64810.1 - 4.7e-08 33.3 0.5 3.8e-07 30.4 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS64810.1 - 2.4e-07 30.7 0.9 5.3e-06 26.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 ETS64810.1 - 8.1e-06 25.3 16.5 0.0014 18.1 0.0 5.9 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 ETS64810.1 - 0.0016 18.7 0.1 0.005 17.1 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS64810.1 - 0.0065 16.6 0.8 3.2 8.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat SRP-alpha_N PF04086.8 ETS64810.1 - 0.24 10.7 21.9 0.65 9.3 15.2 1.7 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal HAUS6_N PF14661.1 ETS64810.1 - 2.2 7.5 13.1 4.7 6.4 9.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Bromodomain PF00439.20 ETS64812.1 - 2.5e-56 187.5 0.3 1.1e-19 70.0 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 ETS64812.1 - 1.5e-06 27.6 0.0 0.0027 16.8 0.0 2.8 1 1 2 3 3 3 2 Peptidase family M1 HEAT_2 PF13646.1 ETS64812.1 - 0.087 13.1 7.7 0.37 11.0 0.0 4.2 4 0 0 4 4 4 0 HEAT repeats SKIP_SNW PF02731.10 ETS64813.1 - 8.1e-64 213.8 3.3 8.1e-64 213.8 2.3 2.2 3 0 0 3 3 3 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.7 ETS64813.1 - 0.003 17.3 12.5 0.0062 16.2 8.7 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Dynamin_M PF01031.15 ETS64814.1 - 6.7e-104 346.8 0.0 3.2e-103 344.6 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 ETS64814.1 - 7.2e-54 182.0 0.0 1.3e-53 181.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 ETS64814.1 - 1e-24 86.2 5.4 1e-24 86.2 3.7 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 ETS64814.1 - 0.0041 17.0 0.8 0.023 14.6 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dus PF01207.12 ETS64814.1 - 0.087 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) NTF2 PF02136.15 ETS64815.1 - 2.5e-34 118.1 0.3 2.8e-34 118.0 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 ETS64815.1 - 0.0057 16.5 0.0 0.0063 16.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3402 PF11882.3 ETS64816.1 - 6.7e-157 522.7 0.0 5.4e-154 513.1 0.0 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 ETS64816.1 - 3.8e-39 134.2 0.0 6.3e-38 130.2 0.0 2.3 1 1 0 1 1 1 1 N1221-like protein Internalin_N PF12354.3 ETS64816.1 - 0.76 9.4 3.0 0.76 9.4 0.3 2.2 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal MFS_1 PF07690.11 ETS64817.1 - 2.4e-47 161.3 38.0 3.5e-47 160.8 26.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.10 ETS64817.1 - 5.1 7.3 10.8 1.4 9.1 1.2 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF202) DUF2530 PF10745.4 ETS64817.1 - 6.7 6.7 12.5 7.9 6.5 1.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) zf-DHHC PF01529.15 ETS64818.1 - 0.53 9.6 1.5 25 4.2 0.0 2.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase Tetraspannin PF00335.15 ETS64818.1 - 0.79 8.9 11.3 0.03 13.6 0.5 2.3 2 0 0 2 2 2 0 Tetraspanin family Antimicrobial11 PF08106.6 ETS64818.1 - 0.85 9.5 4.2 14 5.7 0.1 2.9 1 1 1 2 2 2 0 Formaecin family HK PF02110.10 ETS64819.1 - 5.2e-63 212.4 3.6 3.9e-60 203.0 2.4 2.2 1 1 1 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 ETS64819.1 - 2.2e-44 150.7 0.1 5.5e-44 149.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 ETS64819.1 - 8.3e-05 21.8 0.2 0.00016 21.0 0.1 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PrsW-protease PF13367.1 ETS64819.1 - 0.044 12.9 0.1 0.087 11.9 0.1 1.4 1 0 0 1 1 1 0 Protease prsW family tRNA-synt_1e PF01406.14 ETS64820.1 - 1.1e-121 405.5 0.0 1.6e-121 405.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 ETS64820.1 - 2.4e-09 36.3 0.5 6.7e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETS64820.1 - 4.6e-05 21.6 0.1 0.021 12.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 ETS64820.1 - 0.0018 18.4 2.8 0.0022 18.2 0.0 2.5 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 ETS64820.1 - 0.0095 14.6 0.6 0.022 13.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 ETS64820.1 - 0.04 12.5 0.0 2.4 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) Sec1 PF00995.18 ETS64821.1 - 2.5e-147 491.9 0.0 3.7e-147 491.3 0.0 1.3 1 1 0 1 1 1 1 Sec1 family Ribonuclease_T2 PF00445.13 ETS64822.1 - 1.2e-38 132.6 0.8 1.7e-38 132.1 0.5 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family NTF2 PF02136.15 ETS64822.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Carbpep_Y_N PF05388.6 ETS64822.1 - 0.92 9.6 2.5 15 5.8 0.0 2.6 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide GST_N_3 PF13417.1 ETS64823.1 - 2.4e-09 37.2 0.0 5.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS64823.1 - 4.4e-09 36.1 0.1 9.3e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS64823.1 - 8.6e-07 29.3 0.0 2.3e-06 27.9 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS64823.1 - 0.0015 18.4 0.0 0.0037 17.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Telomere_reg-2 PF10193.4 ETS64824.1 - 1.4e-24 86.5 0.0 4.1e-24 85.0 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein PHD PF00628.24 ETS64825.1 - 1.3e-07 31.1 10.1 2.2e-07 30.4 7.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS64825.1 - 0.0016 17.6 7.1 0.0032 16.7 4.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 ETS64825.1 - 0.0018 17.9 3.5 0.0042 16.7 2.4 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger AAA_13 PF13166.1 ETS64827.1 - 1.4e-06 27.0 109.7 0.00049 18.7 15.5 5.3 3 1 2 5 5 5 4 AAA domain Tropomyosin PF00261.15 ETS64827.1 - 0.00012 21.3 9.2 0.00012 21.3 6.4 9.3 3 3 3 7 7 7 1 Tropomyosin Reo_sigmaC PF04582.7 ETS64827.1 - 0.00026 20.2 1.6 0.00026 20.2 1.1 5.8 3 1 2 6 6 6 4 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 ETS64827.1 - 0.00032 20.5 59.9 0.0016 18.3 14.5 10.8 4 3 6 11 11 11 2 Tropomyosin like Filament PF00038.16 ETS64827.1 - 0.0041 16.6 48.8 0.0041 16.6 33.8 10.2 1 1 5 7 7 7 4 Intermediate filament protein Mto2_bdg PF12808.2 ETS64827.1 - 0.0043 17.1 11.1 0.0043 17.1 7.7 10.7 11 2 0 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region AlphaC_N PF08829.5 ETS64827.1 - 0.0078 15.5 0.3 0.03 13.6 0.2 2.0 1 0 0 1 1 1 1 Alpha C protein N terminal LMSTEN PF07988.7 ETS64827.1 - 0.32 10.3 11.5 1.3 8.3 0.2 4.1 4 0 0 4 4 4 0 LMSTEN motif DUF948 PF06103.6 ETS64827.1 - 1.5 8.7 35.8 0.052 13.4 1.1 7.7 4 1 4 8 8 8 0 Bacterial protein of unknown function (DUF948) Zn_clus PF00172.13 ETS64828.1 - 8.1e-08 32.0 7.8 1.3e-07 31.4 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS64828.1 - 2e-07 30.1 0.4 1.5e-06 27.3 0.0 2.3 3 1 0 3 3 3 1 Fungal specific transcription factor domain Peptidase_M16_C PF05193.16 ETS64829.1 - 9.3e-45 152.5 0.0 1.4e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETS64829.1 - 1.7e-43 147.9 0.0 4.1e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Abhydrolase_6 PF12697.2 ETS64830.1 - 1e-20 74.5 0.2 1.7e-20 73.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS64830.1 - 7e-12 45.3 0.0 1.5e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS64830.1 - 4.5e-06 26.3 0.2 0.0031 17.1 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS64830.1 - 0.00057 19.6 0.2 0.0011 18.7 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 ETS64830.1 - 0.00099 18.4 0.2 1.1 8.5 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 ETS64830.1 - 0.0081 15.6 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 Putative esterase MFS_1 PF07690.11 ETS64831.1 - 3.8e-37 127.8 52.7 2.6e-36 125.0 36.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS64831.1 - 1.6e-12 46.7 7.3 1.6e-12 46.7 5.1 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter COX4 PF02936.9 ETS64831.1 - 0.079 12.6 0.6 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Asp PF00026.18 ETS64832.1 - 2.3e-70 237.3 0.4 2.9e-70 237.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS64832.1 - 5.2e-09 36.2 0.1 1.3e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS64832.1 - 1.4e-06 28.7 1.4 0.0039 17.6 0.0 3.3 2 1 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 ETS64832.1 - 0.015 15.0 0.2 0.069 12.9 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 ETS64832.1 - 0.062 13.2 0.1 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Syja_N PF02383.13 ETS64834.1 - 6.2e-83 278.1 0.0 8.9e-83 277.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 ETS64834.1 - 2.7e-28 99.5 0.0 6.7e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family F-box-like PF12937.2 ETS64835.1 - 2.4e-12 46.3 2.3 2.4e-12 46.3 1.6 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS64835.1 - 7.3e-09 35.0 0.5 7e-08 31.9 0.1 2.6 2 0 0 2 2 2 1 F-box domain ATP_synt_H PF05493.8 ETS64836.1 - 1.3e-20 73.2 4.3 1.4e-20 73.0 3.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 ETS64836.1 - 0.1 11.9 0.8 0.1 11.9 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3093 PF11292.3 ETS64836.1 - 0.54 10.0 3.9 0.6 9.9 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) NAD_binding_2 PF03446.10 ETS64837.1 - 2.8e-18 66.3 0.0 4.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS64837.1 - 1.3e-10 41.3 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 ETS64837.1 - 1.1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 ETS64837.1 - 2.4e-05 24.6 0.0 9.7e-05 22.7 0.0 2.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 ETS64837.1 - 0.005 17.1 0.0 0.061 13.6 0.0 2.5 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS64837.1 - 0.033 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 ETS64837.1 - 0.12 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Rad21_Rec8_N PF04825.8 ETS64838.1 - 2.5e-42 143.2 0.1 4.6e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 ETS64838.1 - 5.6e-16 57.4 0.0 1.5e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 ETS64838.1 - 0.00019 21.1 0.1 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 ScpA/B protein Macoilin PF09726.4 ETS64839.1 - 5.3 5.1 13.6 7.7 4.6 9.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Cyclin_N PF00134.18 ETS64842.1 - 1.8e-44 150.3 0.6 3e-42 143.1 0.6 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETS64842.1 - 4.5e-26 91.0 0.0 4.5e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-MYND PF01753.13 ETS64843.1 - 4.4e-06 26.4 16.0 4.4e-06 26.4 11.1 2.1 2 0 0 2 2 2 1 MYND finger Toxin_3 PF00537.13 ETS64843.1 - 0.27 11.1 6.2 0.54 10.1 4.3 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain CLPTM1 PF05602.7 ETS64844.1 - 4.3e-104 348.6 0.0 9.2e-104 347.5 0.0 1.5 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 ETS64844.1 - 7.7e-05 22.1 0.5 7.7e-05 22.1 0.3 2.2 3 0 0 3 3 3 1 PQ loop repeat DUF456 PF04306.8 ETS64844.1 - 0.025 14.6 3.6 0.1 12.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF456) SecIII_SopE_N PF05364.9 ETS64844.1 - 0.1 12.4 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus MFS_1 PF07690.11 ETS64845.1 - 4.8e-27 94.5 31.1 4.8e-27 94.5 21.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS64845.1 - 8.7e-07 27.8 22.6 4.8e-06 25.4 15.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter AMP-binding PF00501.23 ETS64847.1 - 1.5e-72 244.2 0.0 1.9e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS64847.1 - 4.9e-08 33.7 0.1 1.2e-07 32.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PLU-1 PF08429.6 ETS64848.1 - 2.4e-82 276.5 2.6 2.4e-82 276.5 1.8 2.3 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 ETS64848.1 - 1.8e-42 144.1 0.4 3.5e-42 143.2 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 ETS64848.1 - 1.5e-26 91.8 37.7 1.5e-12 47.0 2.4 4.4 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 ETS64848.1 - 2.8e-19 68.7 0.0 7.5e-19 67.3 0.0 1.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 ETS64848.1 - 1.6e-14 53.1 1.0 2.9e-14 52.2 0.7 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 ETS64848.1 - 1.5e-11 44.1 0.2 1.5e-11 44.1 0.2 2.5 3 0 0 3 3 2 1 C5HC2 zinc finger PHD_2 PF13831.1 ETS64848.1 - 6.1e-05 22.2 24.8 0.025 13.8 2.7 3.9 4 0 0 4 4 4 3 PHD-finger zf-HC5HC2H PF13771.1 ETS64848.1 - 0.0045 17.0 10.3 2.9 8.1 0.1 3.5 3 0 0 3 3 3 2 PHD-like zinc-binding domain TusA PF01206.12 ETS64848.1 - 0.011 15.3 0.3 0.89 9.2 0.1 2.6 2 0 0 2 2 2 0 Sulfurtransferase TusA Fe-ADH_2 PF13685.1 ETS64848.1 - 0.017 14.4 0.1 0.039 13.2 0.1 1.6 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase C1_1 PF00130.17 ETS64848.1 - 0.13 12.0 24.4 0.51 10.0 0.8 4.2 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Thg1 PF04446.7 ETS64848.1 - 0.22 11.1 0.0 0.48 10.0 0.0 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase E1-E2_ATPase PF00122.15 ETS64849.1 - 2.7e-66 222.8 6.8 9.8e-66 221.0 0.5 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 ETS64849.1 - 3.1e-24 86.6 0.9 1.1e-23 84.8 0.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS64849.1 - 3.5e-13 50.1 0.0 6.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS64849.1 - 1.1e-10 40.7 0.0 2.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus YrvL PF14184.1 ETS64849.1 - 0.00073 19.3 4.5 0.00073 19.3 3.1 2.4 2 0 0 2 2 2 1 Regulatory protein YrvL Hydrolase_3 PF08282.7 ETS64849.1 - 0.0009 18.8 0.3 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS64849.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit RPA_C PF08784.6 ETS64851.1 - 1.5e-15 57.4 0.3 3e-15 56.4 0.2 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 ETS64851.1 - 2.2e-08 33.8 0.2 3.5e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GIDE PF12483.3 ETS64851.1 - 0.087 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase MarR_2 PF12802.2 ETS64851.1 - 0.099 12.3 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 MarR family Het-C PF07217.6 ETS64852.1 - 1.8e-230 766.2 0.0 3.6e-230 765.3 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C 6PGD PF00393.14 ETS64853.1 - 5.6e-134 445.8 0.0 6.8e-134 445.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 ETS64853.1 - 1.2e-53 181.3 0.0 1.7e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS64853.1 - 0.028 14.8 0.1 0.053 13.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 ETS64853.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Ub-Mut7C PF14451.1 ETS64853.1 - 0.18 11.3 0.3 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 Mut7-C ubiquitin Sterol-sensing PF12349.3 ETS64855.1 - 7.3e-47 158.6 10.8 1.3e-46 157.8 7.5 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 ETS64855.1 - 2e-17 62.4 5.1 2.9e-17 61.9 3.6 1.1 1 0 0 1 1 1 1 Patched family ADH_zinc_N PF00107.21 ETS64856.1 - 1.3e-11 44.1 0.0 2.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS64856.1 - 1.9e-08 34.0 0.0 4.8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UFD1 PF03152.9 ETS64858.1 - 8.5e-67 223.6 0.0 1.1e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cpn60_TCP1 PF00118.19 ETS64859.1 - 8.9e-140 466.5 11.3 1.2e-139 466.1 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chitin_synth_2 PF03142.10 ETS64860.1 - 1.6e-290 964.0 0.0 2e-290 963.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 ETS64860.1 - 2.9e-17 62.9 1.1 7.5e-17 61.6 0.8 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS64860.1 - 1.6e-15 57.5 0.0 3.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ETS64860.1 - 3.7e-06 26.3 0.0 0.00061 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Cyt-b5 PF00173.23 ETS64860.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 ETS64860.1 - 0.00082 19.0 0.0 0.0031 17.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 4HB_MCP_1 PF12729.2 ETS64860.1 - 8.2 5.7 2.8 2.8 7.2 0.0 1.5 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction ABC_membrane PF00664.18 ETS64861.1 - 4.8e-74 249.2 20.7 2.5e-40 138.6 5.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS64861.1 - 5.8e-51 172.3 0.1 2.2e-31 108.9 0.1 2.9 2 1 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 ETS64861.1 - 1.8e-05 24.8 2.8 0.0057 16.6 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 ETS64861.1 - 4.7e-05 22.7 0.5 0.47 9.6 0.1 3.9 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 ETS64861.1 - 0.00014 21.7 2.5 0.26 11.0 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 ETS64861.1 - 0.00016 21.6 0.1 0.31 11.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 ETS64861.1 - 0.0018 17.7 0.9 2.4 7.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 ETS64861.1 - 0.0025 16.7 0.3 0.26 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 ETS64861.1 - 0.0027 17.1 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 ETS64861.1 - 0.0028 17.5 3.5 0.06 13.1 0.0 2.9 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 ETS64861.1 - 0.003 18.0 1.7 2.2 8.7 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 ETS64861.1 - 0.0047 16.1 0.3 1.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 ETS64861.1 - 0.013 15.5 0.0 7.9 6.3 0.0 3.5 2 2 0 3 3 3 0 AAA domain DUF815 PF05673.8 ETS64861.1 - 0.11 11.4 0.7 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 ETS64861.1 - 0.14 11.5 2.9 9.2 5.5 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain IMPDH PF00478.20 ETS64862.1 - 2.3e-135 451.0 0.0 8.9e-135 449.1 0.0 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Hat1_N PF10394.4 ETS64862.1 - 2.9e-35 121.7 0.0 4.8e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus CBS PF00571.23 ETS64862.1 - 4.2e-19 68.0 0.0 1.1e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 ETS64862.1 - 2.9e-11 43.0 6.8 1.4e-08 34.2 3.9 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 ETS64862.1 - 1.1e-08 34.3 2.5 3e-08 32.9 1.7 1.7 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 ETS64862.1 - 3.7e-08 32.9 1.6 2.5e-07 30.1 1.5 2.0 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 ETS64862.1 - 0.00038 19.5 1.6 0.0007 18.7 1.1 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Acetyltransf_1 PF00583.19 ETS64862.1 - 0.0012 18.7 0.0 0.0039 17.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS64862.1 - 0.0016 18.5 0.0 0.0053 16.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 ETS64862.1 - 0.0026 17.0 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family DUF561 PF04481.7 ETS64862.1 - 0.036 13.0 0.5 0.22 10.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Acetyltransf_7 PF13508.1 ETS64862.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dus PF01207.12 ETS64862.1 - 0.13 11.1 0.7 0.64 8.7 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) RRP7 PF12923.2 ETS64863.1 - 1.8e-32 112.1 3.3 7.6e-32 110.0 0.0 2.8 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 ETS64863.1 - 4.4e-06 26.2 0.0 8.6e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64863.1 - 0.00013 21.9 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.1 ETS64863.1 - 0.43 11.0 4.2 0.42 11.0 0.8 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tim17 PF02466.14 ETS64864.1 - 8e-35 119.6 6.9 9.9e-35 119.3 4.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 ETS64864.1 - 0.08 12.9 0.5 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Nop PF01798.13 ETS64865.1 - 3.2e-58 195.3 0.6 6.6e-58 194.2 0.4 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 ETS64865.1 - 4.5e-27 93.6 0.0 8.1e-27 92.7 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 ETS64865.1 - 6.1e-16 58.3 0.3 2e-15 56.6 0.2 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain EMP24_GP25L PF01105.19 ETS64866.1 - 7e-47 159.4 0.0 9.6e-47 159.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Apocytochr_F_C PF01333.14 ETS64866.1 - 0.098 12.5 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Apocytochrome F, C-terminal CcmD PF04995.9 ETS64866.1 - 0.52 10.0 3.1 1.1 9.0 2.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Ran_BP1 PF00638.13 ETS64867.1 - 2.7e-51 172.7 1.0 4e-51 172.1 0.7 1.2 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 ETS64867.1 - 2.8e-05 23.7 0.9 4.5e-05 23.0 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 ETS64867.1 - 0.00023 20.8 0.9 0.0011 18.6 0.6 1.9 1 1 0 1 1 1 1 WH1 domain Tau95 PF09734.4 ETS64868.1 - 8.9e-47 159.9 0.0 1.1e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF1045 PF06299.7 ETS64868.1 - 0.07 12.8 0.2 8 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Pol_alpha_B_N PF08418.5 ETS64869.1 - 8.6e-53 179.4 0.0 1.2e-52 179.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 ETS64869.1 - 1.4e-23 83.2 0.0 2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF1162 PF06650.7 ETS64870.1 - 1.1e-73 247.9 0.0 9.3e-71 238.2 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 ETS64870.1 - 2.7e-39 133.3 0.2 6.4e-39 132.1 0.1 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 ETS64870.1 - 4e-07 30.1 0.0 1.4e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Methyltransf_16 PF10294.4 ETS64871.1 - 5.5e-17 61.7 0.0 1.3e-16 60.5 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 ETS64871.1 - 0.045 14.5 0.0 0.075 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sec8_exocyst PF04048.9 ETS64872.1 - 2e-39 134.4 0.6 4.2e-39 133.4 0.4 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 ETS64872.1 - 2.8e-06 26.4 0.6 5.2e-06 25.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 ETS64872.1 - 0.00057 19.7 2.3 0.0013 18.5 0.3 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 IpaD PF06511.6 ETS64872.1 - 0.042 12.8 0.7 0.14 11.1 0.5 1.9 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD WIYLD PF10440.4 ETS64872.1 - 0.15 12.0 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Ribosomal_S5_C PF03719.10 ETS64874.1 - 7.8e-16 57.1 0.0 2.2e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 ETS64874.1 - 7.4e-14 51.2 0.8 1.2e-13 50.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF936 PF06075.7 ETS64874.1 - 0.52 9.1 11.3 0.71 8.7 7.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) RRM_1 PF00076.17 ETS64875.1 - 9e-35 118.1 0.0 3.2e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64875.1 - 1.2e-27 95.6 0.0 2.8e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64875.1 - 1e-08 34.8 0.0 0.00084 19.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sororin PF09666.5 ETS64875.1 - 1.8 8.7 5.4 10 6.2 1.1 2.8 2 0 0 2 2 2 0 Sororin protein Complex1_LYR PF05347.10 ETS64877.1 - 0.0011 18.7 0.7 0.0011 18.7 0.5 2.3 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS64877.1 - 0.007 16.5 0.9 0.007 16.5 0.6 2.5 2 0 0 2 2 2 1 Complex1_LYR-like EURL PF06937.6 ETS64877.1 - 0.19 11.1 2.8 0.32 10.3 1.9 1.3 1 0 0 1 1 1 0 EURL protein MSA-2c PF12238.3 ETS64877.1 - 1.1 8.8 9.0 0.096 12.3 2.3 2.1 2 1 0 2 2 2 0 Merozoite surface antigen 2c Bap31 PF05529.7 ETS64877.1 - 4.6 6.6 8.3 7.5 5.9 5.8 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zf-C2H2 PF00096.21 ETS64878.1 - 0.00035 20.7 17.6 0.022 15.1 2.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type SR-25 PF10500.4 ETS64878.1 - 0.21 11.0 8.4 0.4 10.1 5.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C2H2_4 PF13894.1 ETS64878.1 - 0.26 11.6 25.4 0.036 14.3 2.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS64878.1 - 0.41 10.8 9.6 0.14 12.3 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS64878.1 - 5.9 6.9 8.9 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PX PF00787.19 ETS64879.1 - 1.4e-16 60.2 0.0 5e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 ETS64879.1 - 4.6e-08 32.6 0.1 2.3e-07 30.3 0.1 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 ETS64879.1 - 0.0077 15.6 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Glyco_hydro_43 PF04616.9 ETS64880.1 - 1.7e-07 30.5 0.8 2.7e-07 29.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 ETS64880.1 - 0.0093 16.1 5.0 0.036 14.2 3.4 2.0 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Cnd1 PF12717.2 ETS64881.1 - 1.9e-64 216.7 4.1 3.3e-58 196.4 0.0 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 ETS64881.1 - 1.2e-53 181.2 0.0 1.2e-53 181.2 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 ETS64881.1 - 1.3e-10 41.3 1.0 0.00079 19.6 0.0 6.1 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 ETS64881.1 - 1.6e-09 36.9 1.1 3.4 8.0 0.0 7.0 7 0 0 7 7 6 2 HEAT repeat Adaptin_N PF01602.15 ETS64881.1 - 3e-07 29.1 1.5 0.00061 18.2 0.4 3.3 3 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 ETS64881.1 - 1.6e-05 24.0 1.2 8.6e-05 21.6 0.2 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 ETS64881.1 - 0.00065 19.6 0.2 0.044 13.7 0.0 4.1 3 1 1 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Nop14 PF04147.7 ETS64881.1 - 0.0028 15.6 20.4 0.0024 15.9 9.7 3.1 4 0 0 4 4 4 1 Nop14-like family HEAT_EZ PF13513.1 ETS64881.1 - 0.012 16.1 13.8 0.061 13.8 0.1 6.3 5 1 1 6 6 5 0 HEAT-like repeat SPX PF03105.14 ETS64881.1 - 0.022 14.5 2.0 0.018 14.8 0.4 1.6 2 0 0 2 2 2 0 SPX domain SDA1 PF05285.7 ETS64881.1 - 0.098 11.9 22.6 0.0058 15.9 11.0 2.1 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.9 ETS64881.1 - 0.4 8.6 14.6 0.64 7.9 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 ETS64881.1 - 3.4 7.2 25.8 0.53 9.8 13.6 2.4 2 0 0 2 2 2 0 YL1 nuclear protein TPR_14 PF13428.1 ETS64882.1 - 0.044 14.4 12.1 1.9 9.3 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat RNA_pol_I_TF PF04090.7 ETS64882.1 - 0.056 12.7 0.6 0.61 9.3 0.2 2.1 1 1 0 2 2 2 0 RNA polymerase I specific initiation factor CwfJ_C_1 PF04677.10 ETS64883.1 - 3.8e-14 52.3 0.0 7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.1 ETS64883.1 - 7.4e-06 25.3 0.8 1.8e-05 24.0 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle CwfJ_C_2 PF04676.9 ETS64883.1 - 8.3e-05 23.0 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.18 ETS64883.1 - 0.0043 16.9 0.2 0.0043 16.9 0.2 2.4 3 0 0 3 3 3 1 Zinc knuckle VMA21 PF09446.5 ETS64884.1 - 2e-10 40.4 5.4 2.8e-10 39.9 3.8 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1229 PF06797.6 ETS64884.1 - 0.08 11.7 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) ORC2 PF04084.9 ETS64885.1 - 1.1e-79 267.6 0.0 1.5e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PIN_4 PF13638.1 ETS64885.1 - 2.3e-22 79.5 0.0 4.9e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 PIN domain Serglycin PF04360.7 ETS64885.1 - 1.3 8.7 7.6 0.1 12.3 1.6 1.9 2 0 0 2 2 2 0 Serglycin DUF1572 PF07609.6 ETS64890.1 - 0.013 15.0 0.1 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) vATP-synt_AC39 PF01992.11 ETS64890.1 - 0.045 12.8 0.0 0.079 12.0 0.0 1.4 1 1 0 1 1 1 0 ATP synthase (C/AC39) subunit DLH PF01738.13 ETS64892.1 - 2.2e-23 82.6 0.1 3.9e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS64892.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Phosphodiest PF01663.17 ETS64893.1 - 4.6e-71 240.0 0.2 5.6e-71 239.7 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SHNi-TPR PF10516.4 ETS64894.1 - 4.4e-11 41.8 0.2 1.1e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_11 PF13414.1 ETS64894.1 - 2.8e-06 26.8 6.2 0.0053 16.3 0.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 ETS64894.1 - 0.00011 22.0 10.3 0.0027 17.5 0.8 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat MSP1_C PF07462.6 ETS64894.1 - 0.032 12.6 6.5 0.035 12.4 3.8 1.6 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TPR_2 PF07719.12 ETS64894.1 - 0.068 13.1 6.3 3.2 7.8 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Glutaredoxin2_C PF04399.8 ETS64894.1 - 0.14 11.6 0.7 0.99 8.9 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain CHASE3 PF05227.8 ETS64894.1 - 1.7 8.2 13.4 4.4 6.9 0.4 3.3 2 1 1 3 3 3 0 CHASE3 domain TPR_11 PF13414.1 ETS64896.1 - 1.3e-26 91.9 18.2 3.7e-13 48.9 0.1 4.0 3 1 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 ETS64896.1 - 1.5e-23 81.3 2.2 5.3e-08 32.1 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETS64896.1 - 6.3e-22 75.6 10.4 2.4e-06 27.0 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETS64896.1 - 1.5e-13 50.9 13.7 3.5e-08 33.8 0.1 5.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETS64896.1 - 1.9e-13 49.1 0.2 0.0047 16.6 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS64896.1 - 2e-13 49.6 11.3 0.00065 20.1 0.0 6.4 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS64896.1 - 2.9e-13 48.8 3.8 0.0005 20.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS64896.1 - 1.4e-11 44.1 10.7 4.5e-06 26.5 0.0 4.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETS64896.1 - 1.7e-10 41.0 9.2 0.0019 18.4 1.2 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS64896.1 - 1.5e-06 27.5 2.2 0.046 13.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS64896.1 - 3.4e-06 27.1 5.8 0.67 10.5 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS64896.1 - 0.00014 21.8 3.0 0.0025 17.9 0.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 ETS64896.1 - 0.00023 21.1 9.3 0.039 14.0 0.2 4.9 4 1 2 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.12 ETS64896.1 - 0.0082 16.4 12.5 0.12 12.6 1.9 4.2 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 ETS64896.1 - 0.032 14.1 9.2 0.88 9.6 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 ETS64896.1 - 0.13 11.3 1.6 3.6 6.7 0.1 2.8 3 1 0 3 3 3 0 Coatomer epsilon subunit TPR_9 PF13371.1 ETS64896.1 - 0.19 11.5 8.4 2.6 7.9 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat RNase_P_Rpp14 PF01900.14 ETS64897.1 - 5e-20 71.4 0.0 8.8e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family IBR PF01485.16 ETS64898.1 - 9.4e-20 70.2 38.1 2.2e-12 46.6 2.9 4.3 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 ETS64898.1 - 6.5e-10 38.9 5.2 2.1e-09 37.2 3.6 1.9 1 1 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 ETS64898.1 - 2.7e-08 33.5 6.3 2.7e-08 33.5 4.3 4.7 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS64898.1 - 8.6e-05 22.4 7.5 8.6e-05 22.4 5.2 4.5 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS64898.1 - 0.00033 20.2 6.5 0.00033 20.2 4.5 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS64898.1 - 0.0074 16.0 7.7 0.0074 16.0 5.4 4.2 4 0 0 4 4 4 1 zinc-RING finger domain DUF3025 PF11227.3 ETS64898.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Baculo_RING PF05883.6 ETS64898.1 - 4.7 7.0 7.7 0.68 9.7 0.6 2.4 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF3414 PF11894.3 ETS64899.1 - 0 1432.7 0.0 0 1432.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Glyco_hydro_45 PF02015.11 ETS64900.1 - 1.4e-51 175.4 13.8 2.4e-51 174.6 9.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Abhydrolase_3 PF07859.8 ETS64902.1 - 4.9e-36 124.2 0.3 8.7e-36 123.4 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS64902.1 - 2.8e-06 26.3 0.8 4.4e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS64902.1 - 0.009 15.7 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS64902.1 - 0.025 13.2 0.0 5.5 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2424) Spc97_Spc98 PF04130.8 ETS64903.1 - 4.2e-91 305.9 0.0 7e-91 305.1 0.0 1.3 1 1 0 1 1 1 1 Spc97 / Spc98 family Alg6_Alg8 PF03155.10 ETS64904.1 - 6.1e-114 381.4 20.4 3e-52 178.0 0.1 3.1 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family Ribosomal_L37ae PF01780.14 ETS64905.1 - 3e-41 139.1 7.7 3.4e-41 139.0 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-BED PF02892.10 ETS64905.1 - 0.0032 17.1 2.6 0.48 10.2 1.8 2.3 1 1 0 1 1 1 1 BED zinc finger Zn_Tnp_IS1595 PF12760.2 ETS64905.1 - 0.0071 16.1 2.1 0.011 15.5 1.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ETS64905.1 - 0.056 13.1 1.0 0.078 12.6 0.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 ETS64905.1 - 0.082 12.8 2.5 0.33 10.9 0.1 2.4 2 1 0 2 2 2 0 Zinc ribbon domain zf-FCS PF06467.9 ETS64905.1 - 0.11 12.1 2.0 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.5 ETS64905.1 - 0.11 11.9 2.5 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.17 ETS64905.1 - 0.22 11.2 2.6 0.32 10.7 1.8 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 ETS64905.1 - 0.24 11.1 3.2 0.37 10.5 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 ETS64905.1 - 2.4 8.6 6.5 1.7 9.1 1.0 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Ribosomal_L44 PF00935.14 ETS64905.1 - 3.4 7.7 7.6 4.7 7.2 1.9 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Amidase PF01425.16 ETS64906.1 - 4.3e-68 230.1 2.6 1.2e-65 222.1 1.5 2.1 2 0 0 2 2 2 2 Amidase G-alpha PF00503.15 ETS64907.1 - 9.7e-106 353.7 1.5 1.2e-105 353.4 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS64907.1 - 1.1e-06 27.9 0.2 0.022 14.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 ETS64907.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 ETS64907.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MRP-L47 PF06984.8 ETS64908.1 - 4.3e-16 58.6 1.9 9.8e-16 57.4 1.3 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 ETS64908.1 - 0.0061 16.2 0.4 0.062 13.0 0.1 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S24e PF01282.14 ETS64909.1 - 2.5e-32 110.5 0.0 4.2e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e HVSL PF09749.4 ETS64910.1 - 2e-33 115.4 0.0 2.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 ETS64910.1 - 0.00044 19.9 0.1 0.00082 19.1 0.0 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily EFG_II PF14492.1 ETS64910.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II Pkinase PF00069.20 ETS64911.1 - 1.7e-55 187.9 0.0 6e-55 186.1 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64911.1 - 5e-25 88.0 0.0 1.1e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PFK PF00365.15 ETS64912.1 - 1.4e-164 545.8 3.1 2.9e-96 321.7 0.6 3.2 3 0 0 3 3 3 3 Phosphofructokinase PapJ PF14855.1 ETS64912.1 - 0.039 13.4 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Cyclase PF04199.8 ETS64913.1 - 3.4e-14 52.8 2.2 6.1e-14 52.0 1.4 1.5 1 1 0 1 1 1 1 Putative cyclase DUF221 PF02714.10 ETS64914.1 - 2.9e-100 335.2 13.1 5.2e-100 334.4 9.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS64914.1 - 1.8e-38 131.5 4.4 1.8e-38 131.5 3.0 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 ETS64914.1 - 4.6e-21 75.1 0.9 7.9e-21 74.3 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 ETS64914.1 - 9.7e-14 51.0 0.0 2.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein TRAM_LAG1_CLN8 PF03798.11 ETS64916.1 - 2.1e-07 30.7 11.4 2.1e-07 30.7 7.9 1.6 1 1 1 2 2 2 1 TLC domain Aldedh PF00171.17 ETS64917.1 - 6.5e-182 604.9 0.1 7.4e-182 604.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS64917.1 - 0.00019 20.2 0.0 0.0003 19.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS64917.1 - 0.00025 20.3 0.0 0.0018 17.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) GFA PF04828.9 ETS64918.1 - 2.8e-22 78.4 4.6 4.7e-22 77.7 3.2 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 ETS64918.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 2.0 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.1 ETS64918.1 - 0.24 10.9 0.3 0.24 10.9 0.2 2.3 3 0 0 3 3 3 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 ETS64918.1 - 0.48 10.1 0.1 0.48 10.1 0.1 2.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit NOB1_Zn_bind PF08772.6 ETS64918.1 - 1.4 8.7 6.0 0.87 9.4 0.2 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 ETS64918.1 - 1.9 8.0 10.3 0.33 10.4 0.2 2.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain adh_short PF00106.20 ETS64919.1 - 5.1e-35 120.8 0.6 6.6e-35 120.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS64919.1 - 8.9e-28 97.6 0.2 1e-27 97.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS64919.1 - 1.9e-17 63.4 0.5 2.5e-17 63.1 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS64919.1 - 1.1e-05 25.0 0.4 3.4e-05 23.4 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS64919.1 - 0.0019 18.2 0.6 0.0042 17.1 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding HEM4 PF02602.10 ETS64919.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Shikimate_DH PF01488.15 ETS64919.1 - 0.063 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ETS64919.1 - 0.08 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3425 PF11905.3 ETS64920.1 - 2.7e-23 82.3 2.5 5.1e-23 81.4 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Sugar_tr PF00083.19 ETS64921.1 - 1.9e-104 349.7 22.4 2.4e-104 349.4 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS64921.1 - 3.3e-23 81.9 32.6 5.4e-23 81.2 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS64921.1 - 2e-07 29.7 21.8 4.5e-05 22.0 0.5 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 ETS64921.1 - 1.4e-05 23.5 0.4 3e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 ETS64921.1 - 0.0002 20.1 2.4 0.0004 19.1 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) zf-CCCH PF00642.19 ETS64922.1 - 1.2e-12 47.1 14.3 1.1e-06 28.1 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 ETS64922.1 - 0.00018 21.2 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phos_pyr_kin PF08543.7 ETS64922.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DEAD PF00270.24 ETS64923.1 - 2.9e-38 130.9 0.0 5e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS64923.1 - 2.8e-23 81.5 0.0 3.9e-13 49.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 ETS64923.1 - 0.0013 18.6 0.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rxt3 PF08642.5 ETS64924.1 - 2.4e-19 69.6 2.0 3e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 MIP-T3 PF10243.4 ETS64924.1 - 5.6e-08 31.7 15.1 5.6e-08 31.7 10.4 3.1 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 SAPS PF04499.10 ETS64924.1 - 0.029 12.9 0.6 0.045 12.3 0.4 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LCCL PF03815.14 ETS64924.1 - 0.034 14.1 0.0 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 LCCL domain ESCRT-II PF05871.7 ETS64925.1 - 1.3e-47 161.1 0.0 1.9e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit UPRTase PF14681.1 ETS64926.1 - 4.9e-79 264.3 0.0 5.6e-79 264.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 ETS64926.1 - 4.3e-05 23.2 0.0 7.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C2H2_2 PF12756.2 ETS64928.1 - 0.017 15.2 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.1 ETS64928.1 - 0.31 10.7 3.7 3.9 7.2 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 ETS64928.1 - 0.57 9.7 4.7 4.2 7.0 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.21 ETS64928.1 - 7 7.2 10.8 2.7 8.4 0.7 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type LSM PF01423.17 ETS64929.1 - 2.7e-16 58.8 0.0 3.7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.11 ETS64930.1 - 2.8e-28 98.6 24.3 2.8e-28 98.6 16.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS64930.1 - 1.9e-12 46.4 6.1 1.9e-12 46.4 4.2 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter Abhydrolase_6 PF12697.2 ETS64931.1 - 3.2e-20 72.9 0.0 4.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS64931.1 - 1.2e-18 67.2 0.0 4.5e-18 65.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS64931.1 - 7.6e-10 38.4 0.0 4.2e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 ETS64931.1 - 2.4e-09 36.1 0.1 8.8e-08 30.9 0.0 2.5 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 ETS64931.1 - 2.8e-09 36.7 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 ETS64931.1 - 3.3e-09 36.2 0.0 7.3e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 ETS64931.1 - 9.5e-06 25.4 0.0 2.6e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.8 ETS64931.1 - 1.6e-05 23.3 0.2 0.094 10.9 0.1 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.15 ETS64931.1 - 0.0002 20.9 0.0 0.004 16.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 ETS64931.1 - 0.00063 19.3 0.0 0.0061 16.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.6 ETS64931.1 - 0.02 13.4 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.3 ETS64931.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase PTCB-BRCT PF12738.2 ETS64932.1 - 4.3e-18 64.9 1.2 6.7e-14 51.4 0.1 5.0 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.21 ETS64932.1 - 6e-16 58.3 0.0 4.4e-08 33.1 0.0 5.9 6 0 0 6 6 6 2 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.17 ETS64933.1 - 6.5e-13 48.1 0.0 1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64933.1 - 1.2e-10 41.2 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64933.1 - 6.8e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 ETS64933.1 - 3.3e-06 27.4 7.0 3.3e-06 27.4 4.9 2.5 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 APH_6_hur PF04655.9 ETS64933.1 - 0.03 13.4 0.1 0.052 12.7 0.1 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase DUF221 PF02714.10 ETS64934.1 - 8.1e-86 287.8 23.3 1.3e-85 287.0 16.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS64934.1 - 2.7e-38 131.0 0.3 9.4e-38 129.2 0.2 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 ETS64934.1 - 4.6e-18 65.5 0.0 1.1e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) HSP20 PF00011.16 ETS64935.1 - 5.9e-17 61.4 0.4 7.4e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family GvpH PF05455.6 ETS64935.1 - 0.06 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 GvpH PI-PLC-X PF00388.14 ETS64936.1 - 0.0045 16.3 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain BRO1 PF03097.13 ETS64937.1 - 2.1e-102 342.6 0.0 3.2e-102 342.1 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 ETS64937.1 - 4.1e-76 255.7 1.6 8.4e-76 254.7 1.1 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.4 ETS64937.1 - 0.02 14.8 6.0 0.013 15.5 2.1 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein WGG PF10273.4 ETS64938.1 - 3.3e-23 81.5 0.0 5.7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 CDC45 PF02724.9 ETS64938.1 - 0.43 8.5 2.9 0.45 8.4 2.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.19 ETS64940.1 - 3e-81 273.3 21.3 3.5e-81 273.0 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS64940.1 - 1.3e-17 63.5 22.3 1.3e-17 63.5 15.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TPR_4 PF07721.9 ETS64940.1 - 0.096 13.1 0.6 0.22 12.0 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Melibiase PF02065.13 ETS64941.1 - 1.7e-130 435.2 0.0 2.1e-130 434.9 0.0 1.1 1 0 0 1 1 1 1 Melibiase Voltage_CLC PF00654.15 ETS64942.1 - 2.8e-94 316.0 25.7 2.8e-94 316.0 17.8 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel DASH_Hsk3 PF08227.6 ETS64942.1 - 4.9e-11 42.6 0.5 8.9e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like CBS PF00571.23 ETS64942.1 - 0.00019 21.1 0.0 0.00095 18.9 0.0 2.1 2 0 0 2 2 2 1 CBS domain Y_phosphatase2 PF03162.8 ETS64943.1 - 2.7e-49 166.6 0.0 3.1e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 ETS64943.1 - 3.4e-05 24.1 0.0 0.00048 20.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 ETS64943.1 - 0.0054 16.3 0.0 0.009 15.6 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS64943.1 - 0.046 13.0 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase XPG_N PF00752.12 ETS64944.1 - 1.8e-29 101.9 0.0 3.9e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 ETS64944.1 - 2.5e-25 88.3 0.0 7.5e-25 86.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region API5 PF05918.6 ETS64944.1 - 0.26 9.7 5.8 0.42 9.0 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MFS_1 PF07690.11 ETS64945.1 - 6e-45 153.4 46.8 1e-42 146.1 34.0 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS64945.1 - 3.3e-21 75.1 33.2 1.3e-20 73.1 23.2 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS64945.1 - 3.4e-11 42.3 35.3 2.7e-10 39.4 8.6 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS64945.1 - 0.28 10.9 6.4 0.32 10.8 0.3 3.3 3 0 0 3 3 3 0 MFS_1 like family Cullin PF00888.17 ETS64946.1 - 2.5e-142 475.4 0.0 2.3e-133 445.8 0.0 2.3 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 ETS64946.1 - 8.3e-28 96.0 1.8 2.1e-27 94.7 1.3 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Ndufs5 PF10200.4 ETS64946.1 - 0.1 12.5 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF4608 PF15381.1 ETS64947.1 - 0.11 12.6 0.4 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) Hydantoinase_A PF01968.13 ETS64948.1 - 6.1e-88 294.6 1.6 1.1e-87 293.8 1.1 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS64948.1 - 2.2e-51 173.8 0.0 2.8e-49 166.9 0.0 2.6 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region VPS9 PF02204.13 ETS64950.1 - 5.2e-13 48.9 0.0 9.4e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain GATA PF00320.22 ETS64951.1 - 2 7.8 7.0 1.7 8.0 0.2 2.9 2 0 0 2 2 2 0 GATA zinc finger MFS_1 PF07690.11 ETS64952.1 - 1.1e-22 80.2 43.0 8.4e-18 64.2 10.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2370 PF10176.4 ETS64952.1 - 0.26 10.5 4.5 0.58 9.4 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) MFS_1 PF07690.11 ETS64953.1 - 1.6e-36 125.8 31.2 1.6e-36 125.8 21.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.2 ETS64954.1 - 0.0016 18.0 0.0 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS64954.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 ETS64954.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Nop14 PF04147.7 ETS64954.1 - 0.49 8.2 7.2 0.81 7.5 5.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2146 PF10220.4 ETS64954.1 - 0.74 7.7 4.7 1.3 6.9 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Cwf_Cwc_15 PF04889.7 ETS64954.1 - 0.89 9.2 11.2 0.094 12.4 3.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 ETS64954.1 - 2.1 6.2 9.7 3.6 5.4 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 ETS64954.1 - 4.9 6.8 8.4 3 7.5 3.8 2.1 2 0 0 2 2 2 0 FAM176 family EF-hand_1 PF00036.27 ETS64955.1 - 2.3e-41 135.9 12.6 5.5e-10 37.8 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETS64955.1 - 4.8e-37 125.9 3.4 3.2e-20 72.0 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETS64955.1 - 8.3e-33 111.7 12.0 1.3e-16 59.8 0.3 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 ETS64955.1 - 9.4e-31 102.9 7.4 1.7e-09 36.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 ETS64955.1 - 7.2e-28 94.6 7.7 4.5e-07 28.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 ETS64955.1 - 5.9e-14 51.7 0.1 3.1e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETS64955.1 - 6e-10 38.7 1.3 5.3e-05 22.8 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETS64955.1 - 9.8e-09 35.2 0.0 0.00076 19.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 ETS64955.1 - 2e-07 30.5 0.0 0.024 14.2 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 ETS64955.1 - 1.6e-05 24.8 1.0 0.00013 21.9 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 ETS64955.1 - 0.0019 17.8 0.1 0.19 11.2 0.0 2.5 1 1 0 2 2 2 1 Caleosin related protein DUF1103 PF06513.6 ETS64955.1 - 0.003 16.9 2.6 0.0038 16.6 1.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EF-hand_like PF09279.6 ETS64955.1 - 0.0037 17.2 0.5 0.024 14.6 0.1 2.3 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 ETS64955.1 - 0.017 14.8 0.2 1.1 9.0 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB SPATA24 PF15175.1 ETS64955.1 - 0.031 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 MotA_activ PF09114.5 ETS64955.1 - 0.04 13.6 0.2 6.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 ETS64955.1 - 0.043 13.5 0.1 4.1 7.2 0.0 3.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.11 ETS64955.1 - 0.091 12.7 1.0 8.2 6.4 0.0 2.5 3 0 0 3 3 2 0 RNA polymerase Rpb4 SapB_1 PF05184.10 ETS64955.1 - 0.1 12.4 0.7 46 3.9 0.0 3.7 4 0 0 4 4 4 0 Saposin-like type B, region 1 LNS2 PF08235.8 ETS64955.1 - 0.12 11.8 0.1 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 ETS64955.1 - 0.18 12.1 1.0 22 5.4 0.0 2.5 1 1 2 3 3 3 0 Toprim-like UcrQ PF02939.11 ETS64956.1 - 2e-23 81.9 1.8 3e-23 81.4 1.3 1.2 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 ETS64956.1 - 0.094 12.8 0.1 0.3 11.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2741) Fe-ADH PF00465.14 ETS64957.1 - 6.6e-70 235.5 0.3 8.6e-70 235.1 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETS64957.1 - 2e-17 63.3 0.0 9.7e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Transposase_24 PF03004.9 ETS64957.1 - 0.0064 16.3 0.3 0.059 13.2 0.3 2.0 2 0 0 2 2 2 1 Plant transposase (Ptta/En/Spm family) DHQ_synthase PF01761.15 ETS64957.1 - 0.12 11.3 1.9 6.8 5.5 0.0 2.9 2 1 1 3 3 3 0 3-dehydroquinate synthase AAA_16 PF13191.1 ETS64957.1 - 0.12 12.3 0.3 4.3 7.2 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF2296 PF10058.4 ETS64958.1 - 2.1e-24 85.0 0.2 3.4e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Histone PF00125.19 ETS64959.1 - 1.7e-30 104.9 1.6 1.4e-28 98.8 0.3 2.4 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETS64959.1 - 1.8e-05 24.8 0.1 5.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 ETS64959.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 ETS64959.1 - 0.019 14.6 0.1 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpc82 PF05645.8 ETS64959.1 - 0.13 11.8 0.3 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 KorB PF08535.5 ETS64960.1 - 0.039 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 KorB domain WD40 PF00400.27 ETS64961.1 - 5.1e-35 118.0 0.3 1e-06 28.3 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETS64961.1 - 4.6e-07 29.7 0.6 3.8e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Tox-GHH PF15636.1 ETS64961.1 - 0.62 9.7 3.3 26 4.5 0.0 3.7 4 0 0 4 4 4 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin HPP PF04982.8 ETS64962.1 - 4.6e-37 126.5 6.1 8.9e-37 125.5 4.2 1.5 1 0 0 1 1 1 1 HPP family YL1_C PF08265.6 ETS64962.1 - 0.023 14.2 0.3 0.062 12.8 0.1 1.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain CoA_binding_3 PF13727.1 ETS64962.1 - 0.031 14.0 0.2 0.075 12.8 0.2 1.7 1 0 0 1 1 1 0 CoA-binding domain Fis1_TPR_C PF14853.1 ETS64963.1 - 8e-25 86.4 0.6 1.3e-24 85.8 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 ETS64963.1 - 1.1e-16 59.7 0.0 2.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 ETS64963.1 - 0.00033 20.3 0.2 0.0008 19.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS64963.1 - 0.0028 18.2 0.0 0.0073 16.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS64963.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.1 ETS64963.1 - 0.091 12.7 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat PX PF00787.19 ETS64964.1 - 2.1e-21 75.8 0.4 3.9e-21 74.9 0.3 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 ETS64964.1 - 4e-06 26.2 0.4 0.75 8.9 0.0 3.2 3 0 0 3 3 3 3 Vps5 C terminal like BAR PF03114.13 ETS64964.1 - 0.01 15.3 0.0 0.039 13.4 0.0 1.9 1 1 0 1 1 1 0 BAR domain Clathrin PF00637.15 ETS64965.1 - 6.3e-210 687.2 27.2 5.2e-33 113.6 0.1 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 ETS64965.1 - 2.5e-34 115.2 2.9 7.7e-06 25.8 0.0 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 ETS64965.1 - 3.2e-32 110.2 0.1 1.1e-31 108.5 0.0 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 ETS64965.1 - 4e-11 41.6 0.1 1.1e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 ETS64965.1 - 0.0022 16.8 5.6 0.16 10.7 0.0 4.8 5 0 0 5 5 5 1 Coatomer WD associated region TPR_2 PF07719.12 ETS64965.1 - 0.0057 16.4 5.0 33 4.7 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS64965.1 - 0.02 14.5 2.9 14 5.5 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS64965.1 - 0.052 13.4 11.1 1.4 8.8 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS64965.1 - 0.054 14.1 10.9 68 4.5 0.1 8.7 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS64965.1 - 0.63 9.9 7.5 32 4.6 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 ETS64966.1 - 1.8e-43 147.8 0.0 3e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS64966.1 - 2.9e-07 30.6 0.0 8.1e-06 25.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 ETS64966.1 - 5.8e-07 29.5 0.0 4.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 ETS64966.1 - 5.9e-07 29.2 0.1 1.3e-05 24.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS64966.1 - 2.8e-06 27.4 0.0 0.001 19.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS64966.1 - 8.5e-06 24.9 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETS64966.1 - 0.00019 21.0 0.1 0.00048 19.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 ETS64966.1 - 0.00061 18.7 0.0 0.0016 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 ETS64966.1 - 0.0009 20.0 1.2 0.0028 18.4 0.3 2.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 ETS64966.1 - 0.0015 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETS64966.1 - 0.0024 17.0 0.0 0.0049 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 ETS64966.1 - 0.0031 16.2 0.0 0.0057 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 ETS64966.1 - 0.0032 17.3 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETS64966.1 - 0.0033 16.8 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 ETS64966.1 - 0.0048 17.0 0.0 0.0099 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 ETS64966.1 - 0.0055 16.3 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS64966.1 - 0.0057 16.9 1.4 0.017 15.3 0.0 2.5 3 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 ETS64966.1 - 0.0076 15.7 0.0 0.028 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF4200 PF13863.1 ETS64966.1 - 0.0086 16.0 0.7 0.0086 16.0 0.5 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) Zeta_toxin PF06414.7 ETS64966.1 - 0.0098 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 ETS64966.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YkyA PF10368.4 ETS64966.1 - 0.011 15.0 0.9 0.021 14.1 0.6 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Arch_ATPase PF01637.13 ETS64966.1 - 0.013 15.1 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 ETS64966.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 ETS64966.1 - 0.018 14.8 0.0 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 ETS64966.1 - 0.029 13.7 0.2 0.17 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 ETS64966.1 - 0.03 13.9 0.0 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 ETS64966.1 - 0.032 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 ETS64966.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS64966.1 - 0.042 12.9 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 ETS64966.1 - 0.049 13.6 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 ETS64966.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 ETS64966.1 - 0.06 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 ETS64966.1 - 0.083 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 ETS64966.1 - 0.099 12.1 0.2 0.38 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS64966.1 - 0.19 12.0 3.6 6.3 7.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain TPR_1 PF00515.23 ETS64966.1 - 7.2 6.4 6.8 0.6 9.8 0.6 2.3 3 0 0 3 3 1 0 Tetratricopeptide repeat GPI-anchored PF10342.4 ETS64967.1 - 4.9e-10 39.7 0.4 7e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 ETS64967.1 - 0.035 13.6 0.1 0.053 13.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3372 PF11852.3 ETS64967.1 - 0.062 12.4 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) PH PF00169.24 ETS64968.1 - 0.00074 19.6 0.0 1.1 9.4 0.0 3.0 3 0 0 3 3 3 2 PH domain BSP_II PF05432.6 ETS64968.1 - 0.037 13.2 3.8 0.097 11.9 2.6 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 ETS64968.1 - 0.039 13.4 0.9 0.088 12.3 0.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETS64968.1 - 1.5 9.1 7.0 4.4 7.6 4.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Methyltransf_16 PF10294.4 ETS64969.1 - 6.9e-16 58.1 0.0 1.1e-07 31.5 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 ETS64969.1 - 0.0002 21.1 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS64969.1 - 0.071 13.7 0.0 0.18 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_63 PF03200.11 ETS64970.1 - 4e-08 31.6 2.6 3.2e-06 25.3 0.1 4.1 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase Pro_isomerase PF00160.16 ETS64971.1 - 6.8e-34 117.3 0.0 1.3e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD XAP5 PF04921.9 ETS64971.1 - 1 8.8 6.0 0.11 12.0 1.1 1.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator TFIIA PF03153.8 ETS64971.1 - 2.1 8.1 18.7 2.9 7.7 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETS64971.1 - 7.9 4.6 11.1 8.7 4.4 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 ETS64971.1 - 9.1 6.0 9.7 16 5.2 6.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NUDIX PF00293.23 ETS64972.1 - 1.7e-11 43.8 0.0 2.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FAD_binding_3 PF01494.14 ETS64972.1 - 0.095 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RRM_1 PF00076.17 ETS64973.1 - 3.3e-15 55.4 0.1 6.2e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64973.1 - 1.9e-12 46.9 0.0 3.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64973.1 - 1.7e-10 40.5 0.1 3.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpl-7 PF08230.6 ETS64973.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain CS PF04969.11 ETS64974.1 - 2.2e-06 28.0 0.0 4.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 CS domain ProQ PF04352.8 ETS64974.1 - 0.04 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 ProQ/FINO family DAGAT PF03982.8 ETS64975.1 - 1e-104 349.4 0.0 1.3e-104 349.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAO PF01266.19 ETS64976.1 - 5.5e-45 153.8 0.9 8.8e-45 153.1 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS64976.1 - 1.3e-11 44.0 3.6 7.6e-07 28.3 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 ETS64976.1 - 1.4e-07 31.5 0.2 0.0025 17.7 0.2 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS64976.1 - 9.7e-06 24.6 0.2 0.023 13.5 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 ETS64976.1 - 1.2e-05 25.1 0.2 0.00012 21.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS64976.1 - 2.7e-05 22.8 0.2 0.068 11.6 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein 3HCDH_N PF02737.13 ETS64976.1 - 8.9e-05 22.2 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 ETS64976.1 - 0.00012 21.8 1.1 0.09 12.5 0.1 2.5 1 1 1 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS64976.1 - 0.00038 20.8 0.0 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS64976.1 - 0.00048 19.2 0.1 0.0021 17.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS64976.1 - 0.00056 20.0 0.0 1.2 9.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS64976.1 - 0.0019 17.2 0.2 0.015 14.2 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 ETS64976.1 - 0.005 15.9 0.1 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GDI PF00996.13 ETS64976.1 - 0.0097 14.2 0.0 2.7 6.2 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_2 PF03446.10 ETS64976.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.9 ETS64976.1 - 0.024 13.2 0.7 0.066 11.8 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase XdhC_C PF13478.1 ETS64976.1 - 0.046 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 ETS64976.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF1115 PF06544.7 ETS64977.1 - 4.3e-07 29.6 0.0 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1115) ETC_C1_NDUFA5 PF04716.9 ETS64978.1 - 4e-16 58.2 2.2 8.6e-16 57.2 1.5 1.6 1 1 0 1 1 1 1 ETC complex I subunit conserved region Cast PF10174.4 ETS64978.1 - 0.0078 14.3 1.7 0.0089 14.1 1.2 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone WW PF00397.21 ETS64979.1 - 0.015 15.1 1.1 0.038 13.8 0.7 1.7 1 0 0 1 1 1 0 WW domain Pex14_N PF04695.8 ETS64979.1 - 4.4 7.3 9.4 5.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 ETS64980.1 - 4.4e-68 229.2 0.0 1.2e-67 227.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS64980.1 - 1.4e-33 116.0 0.0 2.3e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HIG_1_N PF04588.8 ETS64980.1 - 0.00022 20.8 0.9 0.00053 19.6 0.6 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region APH PF01636.18 ETS64980.1 - 0.00044 20.0 0.0 0.0032 17.2 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS64980.1 - 0.01 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETS64980.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 ETS64980.1 - 0.037 13.6 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF504 PF04457.7 ETS64981.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF504) Methyltransf_10 PF05971.7 ETS64982.1 - 4.8e-41 140.8 0.2 8.8e-40 136.7 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF890) CENP-O PF09496.5 ETS64982.1 - 2.9e-25 88.3 0.0 5.3e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Methyltransf_18 PF12847.2 ETS64982.1 - 0.00011 22.7 0.1 0.00059 20.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain ABC_membrane_2 PF06472.10 ETS64984.1 - 3.4e-98 328.2 3.1 3.4e-98 328.2 2.2 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 ETS64984.1 - 5.2e-16 59.1 0.0 1.7e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.7 ETS64984.1 - 0.0043 16.1 0.0 0.0083 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 ETS64984.1 - 0.0062 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS64984.1 - 0.02 15.6 0.0 0.061 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS64984.1 - 0.021 14.7 0.0 0.072 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETS64984.1 - 0.022 14.2 0.0 0.072 12.6 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 ETS64984.1 - 0.025 14.3 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 ETS64984.1 - 0.029 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 ETS64984.1 - 0.056 13.7 0.3 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 ETS64984.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS64984.1 - 0.078 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 ETS64984.1 - 0.089 10.1 0.0 0.16 9.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sigma54_activat PF00158.21 ETS64984.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.14 ETS64984.1 - 0.14 11.4 0.0 10 5.3 0.0 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain M-factor PF03855.8 ETS64986.1 - 0.013 15.4 0.3 0.034 14.1 0.2 1.7 1 0 0 1 1 1 0 M-factor Peptidase_S10 PF00450.17 ETS64987.1 - 5.5e-97 325.5 5.7 9.7e-97 324.7 3.9 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Ribosomal_L33 PF00471.15 ETS64987.1 - 6.6e-13 48.6 0.0 1.9e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L33 Ran_BP1 PF00638.13 ETS64989.1 - 2.5e-22 79.1 0.1 5.3e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain DUF1188 PF06690.6 ETS64989.1 - 0.069 12.2 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) vATP-synt_E PF01991.13 ETS64990.1 - 6e-59 198.6 13.3 7e-59 198.4 9.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit eIF3g PF12353.3 ETS64991.1 - 2.3e-44 150.3 5.3 3.7e-44 149.7 3.7 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 ETS64991.1 - 4.9e-19 67.7 0.0 9.2e-19 66.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS64991.1 - 1.8e-15 56.6 0.0 3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS64991.1 - 1.3e-09 37.7 0.0 4.2e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS64991.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribonucleas_3_3 PF14622.1 ETS64992.1 - 2.6e-27 95.3 0.0 3.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 ETS64992.1 - 0.0023 18.3 0.0 0.0075 16.6 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain NUDIX_4 PF14815.1 ETS64993.1 - 5.9e-19 67.5 0.0 1.7e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 ETS64993.1 - 6.4e-19 68.2 0.0 1.6e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETS64993.1 - 9.4e-07 28.2 0.1 3.2e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 ETS64993.1 - 0.00059 19.9 9.4 0.00059 19.9 6.5 2.1 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III Whib PF02467.11 ETS64993.1 - 0.059 13.6 2.8 0.12 12.7 0.5 2.5 2 0 0 2 2 2 0 Transcription factor WhiB NDUF_B8 PF05821.6 ETS64995.1 - 2.4e-08 33.8 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) ELO PF01151.13 ETS64997.1 - 1.7e-59 201.1 19.2 2.2e-59 200.8 13.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2231 PF09990.4 ETS64997.1 - 0.11 12.7 2.2 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Cpn60_TCP1 PF00118.19 ETS64998.1 - 3.6e-144 480.9 0.3 4.2e-144 480.7 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AP_endonuc_2 PF01261.19 ETS64998.1 - 0.044 13.0 0.1 0.37 10.0 0.0 2.4 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel DUF448 PF04296.8 ETS64999.1 - 0.0012 18.4 0.2 0.24 11.0 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF448) Fes1 PF08609.5 ETS65000.1 - 1.1e-21 77.0 1.0 4e-21 75.3 0.7 1.9 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 ETS65000.1 - 2.7e-13 49.9 6.6 6.7e-06 26.3 0.4 3.1 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 ETS65000.1 - 6.2e-07 28.9 0.1 0.25 11.5 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 ETS65000.1 - 5.7e-06 26.6 2.5 0.00013 22.2 0.1 3.6 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 ETS65000.1 - 0.00075 19.3 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 ETS65000.1 - 0.0011 17.4 0.2 0.0034 15.7 0.1 1.7 1 1 1 2 2 2 1 Adaptin N terminal region Arm PF00514.18 ETS65000.1 - 0.0034 17.1 0.2 1.5 8.7 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat zf-RING_2 PF13639.1 ETS65001.1 - 1.4e-12 47.1 7.7 3.1e-12 46.1 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS65001.1 - 1.8e-11 44.0 6.1 3.5e-11 43.0 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS65001.1 - 4.5e-08 32.6 7.0 8.7e-08 31.7 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS65001.1 - 3.4e-07 30.0 3.3 7.5e-07 28.9 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 ETS65001.1 - 1.2e-06 28.0 4.1 2.1e-06 27.2 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS65001.1 - 6.7e-06 26.0 6.5 1.3e-05 25.1 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS65001.1 - 1.1e-05 25.0 5.3 2e-05 24.2 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS65001.1 - 0.016 14.9 2.5 0.038 13.6 1.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 ETS65001.1 - 0.02 14.9 5.9 0.046 13.7 4.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 ETS65001.1 - 0.1 12.2 4.4 0.27 10.8 3.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 ETS65001.1 - 0.15 12.0 4.9 0.15 12.0 2.1 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.24 ETS65001.1 - 0.18 11.5 5.5 0.34 10.6 3.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 ETS65001.1 - 0.2 11.8 3.2 0.41 10.8 2.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain ILVD_EDD PF00920.16 ETS65001.1 - 0.25 9.6 0.0 0.42 8.9 0.0 1.2 1 0 0 1 1 1 0 Dehydratase family zf-C3HC4_4 PF15227.1 ETS65001.1 - 0.44 10.4 4.0 0.92 9.4 2.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PRP3 PF08572.5 ETS65003.1 - 2e-60 203.9 2.5 2e-60 203.9 1.7 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 ETS65003.1 - 1.1e-28 99.4 0.0 2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PAPS_reduct PF01507.14 ETS65004.1 - 6.3e-20 71.7 0.1 3e-14 53.2 0.0 3.0 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family CDC45 PF02724.9 ETS65005.1 - 0.6 8.0 19.1 0.049 11.6 5.6 2.1 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.7 ETS65005.1 - 0.79 8.9 15.8 0.75 9.0 2.4 2.1 2 0 0 2 2 2 0 SDA1 Macoilin PF09726.4 ETS65005.1 - 2.5 6.2 18.0 3.8 5.6 12.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2146 PF10220.4 ETS65005.1 - 5.9 4.7 7.8 10 3.9 5.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF1510 PF07423.6 ETS65005.1 - 6.5 6.0 12.1 1 8.6 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Sec1 PF00995.18 ETS65006.1 - 7.4e-162 539.8 0.0 9.5e-162 539.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF1045 PF06299.7 ETS65006.1 - 0.039 13.6 0.4 0.088 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) NIF PF03031.13 ETS65007.1 - 4.2e-50 169.5 0.0 6.4e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SKI PF01202.17 ETS65009.1 - 2e-12 47.2 0.0 1.7e-09 37.7 0.0 2.3 1 1 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.1 ETS65009.1 - 3.5e-08 33.4 0.3 8.5e-07 28.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS65009.1 - 5e-08 33.7 0.0 1.6e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS65009.1 - 9.1e-06 26.0 0.0 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 ETS65009.1 - 0.00021 21.2 0.0 0.00069 19.5 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_16 PF13191.1 ETS65009.1 - 0.00036 20.5 0.2 0.00069 19.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS65009.1 - 0.0013 18.8 0.8 0.21 11.7 0.1 2.8 1 1 1 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS65009.1 - 0.0098 15.3 0.9 0.025 14.0 0.6 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family APS_kinase PF01583.15 ETS65009.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.15 ETS65009.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_29 PF13555.1 ETS65009.1 - 0.021 14.3 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS65009.1 - 0.024 14.9 0.1 0.041 14.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 ETS65009.1 - 0.025 13.5 0.0 0.079 11.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Herpes_Helicase PF02689.9 ETS65009.1 - 0.028 12.1 0.0 0.069 10.8 0.0 1.5 2 0 0 2 2 2 0 Helicase AAA PF00004.24 ETS65009.1 - 0.031 14.4 0.2 0.085 13.0 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 ETS65009.1 - 0.06 13.3 1.4 0.34 10.8 0.4 2.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS65009.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 ETS65009.1 - 0.078 12.3 1.2 0.33 10.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain PRK PF00485.13 ETS65009.1 - 0.086 12.3 0.1 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 ETS65009.1 - 0.21 11.0 1.3 2.5 7.4 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain CbiA PF01656.18 ETS65009.1 - 2 7.7 4.3 10 5.4 3.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L23 PF00276.15 ETS65010.1 - 1.9e-07 30.9 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Pkinase PF00069.20 ETS65012.1 - 4.1e-63 212.9 0.0 5.2e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65012.1 - 2.4e-33 115.3 0.0 3.2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS65012.1 - 1e-08 34.5 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS65012.1 - 0.00083 19.1 0.6 0.0021 17.8 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS65012.1 - 0.0051 15.8 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Histidinol_dh PF00815.15 ETS65013.1 - 2.3e-162 540.3 5.0 2.3e-159 530.4 3.5 2.3 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 ETS65013.1 - 9.4e-24 82.8 0.2 1.7e-23 82.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 ETS65013.1 - 5.2e-11 42.6 3.1 6.2e-11 42.4 0.2 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Peptidase_S10 PF00450.17 ETS65014.1 - 2e-95 320.4 0.0 3.2e-95 319.7 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS65014.1 - 6e-05 23.0 0.4 0.00022 21.1 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 ETS65015.1 - 2.7e-33 114.7 0.0 4.1e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS65015.1 - 1.5e-11 44.2 0.3 3.3e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NPBW PF15180.1 ETS65015.1 - 0.084 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Neuropeptides B and W SAB PF04382.8 ETS65015.1 - 1.2 8.8 4.8 0.31 10.7 0.2 2.5 3 0 0 3 3 3 0 SAB domain AhpC-TSA_2 PF13911.1 ETS65016.1 - 6.2e-13 48.6 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 ETS65016.1 - 5.2e-08 32.6 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS65016.1 - 1.7e-07 30.8 0.0 3.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Redoxin GCV_T PF01571.16 ETS65017.1 - 3.4e-17 62.5 0.0 1.1e-16 60.9 0.0 1.9 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETS65017.1 - 5.7e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HMG_box PF00505.14 ETS65019.1 - 4.2e-20 71.7 13.7 6.8e-12 45.4 0.4 3.6 2 2 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS65019.1 - 3.9e-18 65.5 11.8 4.4e-11 42.9 0.2 3.0 3 0 0 3 3 3 2 HMG-box domain Tol_Tol_Ttg2 PF05494.7 ETS65019.1 - 0.031 13.8 1.0 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 KRAB PF01352.22 ETS65019.1 - 1.7 8.1 3.3 7 6.1 0.2 2.3 2 0 0 2 2 2 0 KRAB box TraG_N PF07916.6 ETS65020.1 - 0.039 12.4 0.0 0.052 11.9 0.0 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Sporozoite_P67 PF05642.6 ETS65020.1 - 0.12 10.1 0.4 0.17 9.7 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen KH_1 PF00013.24 ETS65021.1 - 1.5e-09 37.3 0.1 1.4e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 ETS65021.1 - 1.4e-05 24.6 4.2 0.00025 20.6 0.2 2.7 2 0 0 2 2 2 2 KH domain PALP PF00291.20 ETS65021.1 - 0.0058 15.9 0.6 0.0058 15.9 0.4 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Trp_repressor PF01371.14 ETS65021.1 - 0.057 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein DUF1769 PF08588.5 ETS65022.1 - 1.3e-24 85.9 0.1 3.2e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) GCS PF03074.11 ETS65023.1 - 7.9e-164 545.0 0.0 2.8e-130 434.6 0.0 2.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase UPF0278 PF08745.6 ETS65023.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 UPF0278 family CDC14 PF08045.6 ETS65024.1 - 0.001 18.2 0.3 0.055 12.5 0.1 2.4 3 0 0 3 3 3 2 Cell division control protein 14, SIN component BRAP2 PF07576.7 ETS65025.1 - 2.3e-24 85.0 0.1 4.8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 ETS65025.1 - 6.2e-19 67.8 5.2 6.2e-19 67.8 3.6 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 ETS65025.1 - 8e-09 35.1 10.3 8e-09 35.1 7.2 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS65025.1 - 8.4e-05 22.1 8.8 8.4e-05 22.1 6.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS65025.1 - 0.0001 22.2 9.9 0.0001 22.2 6.8 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS65025.1 - 0.0004 20.4 5.8 0.0004 20.4 4.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 ETS65025.1 - 0.0015 18.1 4.2 0.005 16.5 1.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger RRM_6 PF14259.1 ETS65025.1 - 0.0025 17.7 0.1 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 ETS65025.1 - 0.041 13.4 5.8 0.11 12.0 4.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 ETS65025.1 - 0.094 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_1 PF00170.16 ETS65025.1 - 0.18 11.8 5.8 0.05 13.5 1.4 2.1 2 1 0 2 2 1 0 bZIP transcription factor Phage_GP20 PF06810.6 ETS65025.1 - 0.38 10.1 10.1 2.8 7.3 6.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Synaptobrevin PF00957.16 ETS65025.1 - 0.56 9.8 1.4 1 8.9 1.0 1.4 1 0 0 1 1 1 0 Synaptobrevin MbeD_MobD PF04899.7 ETS65025.1 - 1.6 8.7 7.2 1.1 9.2 0.2 2.6 2 0 0 2 2 2 0 MbeD/MobD like DUF972 PF06156.8 ETS65025.1 - 2.6 8.4 8.4 1.7 9.0 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 ETS65025.1 - 3.5 7.1 13.1 6.9 6.2 9.1 1.4 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 ETS65025.1 - 7.4 6.4 13.5 1.5 8.7 2.3 3.1 3 0 0 3 3 3 0 Basic region leucine zipper Aldo_ket_red PF00248.16 ETS65026.1 - 4.7e-56 189.6 0.1 5.5e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPP_enzyme_N PF02776.13 ETS65027.1 - 2.6e-35 121.4 0.1 4.2e-35 120.7 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETS65027.1 - 5.4e-28 97.4 0.0 1.2e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 ETS65027.1 - 3.9e-14 52.4 0.0 2.8e-13 49.6 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TauD PF02668.11 ETS65028.1 - 4.2e-52 177.3 0.2 6.6e-52 176.7 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family YhhN PF07947.9 ETS65028.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 YhhN-like protein TP_methylase PF00590.15 ETS65030.1 - 1.2e-38 132.9 0.7 3e-38 131.6 0.5 1.7 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 ETS65030.1 - 8.7e-11 42.0 0.1 9.6e-10 38.6 0.1 2.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 ETS65030.1 - 3.9e-08 32.4 0.4 0.00012 21.3 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 ETS65030.1 - 2.4e-05 23.1 0.1 4.6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central LEAP-2 PF07359.6 ETS65030.1 - 0.085 12.5 0.1 0.27 10.9 0.1 1.9 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) PAT1 PF09770.4 ETS65030.1 - 5 5.2 10.6 7.4 4.6 7.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 COX17 PF05051.8 ETS65031.1 - 1.5e-16 60.1 8.4 2.2e-16 59.5 5.9 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 ETS65031.1 - 0.029 14.2 4.1 0.05 13.4 2.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Peptidase_M16_C PF05193.16 ETS65032.1 - 2.9e-20 72.6 0.0 4.7e-13 49.2 0.0 3.2 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETS65032.1 - 2.4e-06 27.3 0.0 6.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sdh_cyt PF01127.17 ETS65033.1 - 2.1e-25 88.8 4.1 2.8e-25 88.5 2.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Exonuc_VII_L PF02601.10 ETS65034.1 - 4.2 6.4 17.4 6 5.9 12.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DNA_pol_A PF00476.15 ETS65035.1 - 6.6e-90 301.4 0.0 1.1e-89 300.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A WD40 PF00400.27 ETS65036.1 - 1.2e-06 28.1 10.1 0.0033 17.2 0.3 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat RF-1 PF00472.15 ETS65037.1 - 1.3e-16 60.4 1.5 2e-16 59.8 1.0 1.3 1 0 0 1 1 1 1 RF-1 domain KH_3 PF13014.1 ETS65037.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 KH domain adh_short PF00106.20 ETS65038.1 - 1.9e-27 96.2 0.1 7.5e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETS65038.1 - 2.2e-15 57.0 0.0 1.4e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS65038.1 - 5e-08 32.8 0.2 5.2e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 ETS65038.1 - 0.0023 17.7 0.1 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 ETS65038.1 - 0.01 15.2 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Spt20 PF12090.3 ETS65039.1 - 4.5e-37 127.1 0.0 4.5e-37 127.1 0.0 4.3 4 2 0 4 4 4 1 Spt20 family MIP-T3 PF10243.4 ETS65039.1 - 0.57 8.5 56.9 1.2 7.4 39.4 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NDK PF00334.14 ETS65040.1 - 2.8e-33 114.5 0.0 5.8e-33 113.5 0.0 1.4 2 0 0 2 2 2 1 Nucleoside diphosphate kinase Cnd2 PF05786.9 ETS65041.1 - 2.1e-146 489.4 0.0 2.1e-146 489.4 0.0 2.1 1 1 0 2 2 2 1 Condensin complex subunit 2 PBP1_TM PF14812.1 ETS65041.1 - 0.28 11.4 32.7 0.77 10.1 6.5 3.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 ETS65041.1 - 9.7 6.4 21.7 2.2 8.4 1.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF2462 PF09495.5 ETS65042.1 - 8.1e-22 77.7 12.8 8.1e-22 77.7 8.9 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Y_phosphatase2 PF03162.8 ETS65043.1 - 2.4e-58 196.1 0.0 5.4e-58 195.0 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 ETS65043.1 - 8.7e-08 32.5 0.0 2.9e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 ETS65043.1 - 0.00027 20.5 0.0 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS65043.1 - 0.00065 19.0 0.0 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PolyA_pol PF01743.15 ETS65044.1 - 1.3e-21 77.0 0.0 2.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 ETS65044.1 - 7.5e-05 22.2 0.1 0.00021 20.8 0.1 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A SRP19 PF01922.12 ETS65045.1 - 3.7e-19 69.0 0.0 7.5e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein DUF3681 PF12442.3 ETS65046.1 - 0.2 11.8 2.6 0.53 10.4 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) CN_hydrolase PF00795.17 ETS65047.1 - 3.9e-26 91.5 0.0 6.4e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Exo_endo_phos PF03372.18 ETS65048.1 - 1.1e-24 87.7 0.1 2.7e-24 86.4 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 ETS65048.1 - 3.8e-05 23.3 3.0 0.005 16.6 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat NUDIX PF00293.23 ETS65049.1 - 7.2e-10 38.6 0.0 1.6e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 NUDIX domain Pex14_N PF04695.8 ETS65051.1 - 0.99 9.4 7.6 2.1 8.3 5.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 ETS65051.1 - 1.8 6.7 19.1 2.2 6.4 13.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Serglycin PF04360.7 ETS65051.1 - 1.9 8.1 18.3 12 5.6 12.7 2.4 1 1 0 1 1 1 0 Serglycin LtrA PF06772.6 ETS65052.1 - 2e-19 69.7 10.1 4e-10 39.1 4.0 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2207 PF09972.4 ETS65052.1 - 0.045 12.3 0.9 0.066 11.7 0.3 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RNB PF00773.14 ETS65053.1 - 4e-49 167.6 0.0 8.8e-49 166.5 0.0 1.6 1 1 0 1 1 1 1 RNB domain Ras PF00071.17 ETS65054.1 - 4e-35 120.5 0.1 5.1e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS65054.1 - 3.6e-22 79.0 0.0 1.4e-21 77.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS65054.1 - 1.1e-07 31.3 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS65054.1 - 4.3e-07 29.3 0.1 5.4e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS65054.1 - 0.00026 20.4 0.0 0.0019 17.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS65054.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 ETS65054.1 - 0.071 11.7 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit DLIC PF05783.6 ETS65054.1 - 0.078 11.6 0.2 0.75 8.3 0.0 1.9 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) SRPRB PF09439.5 ETS65054.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAPA-1 PF04795.7 ETS65055.1 - 8.8e-15 55.1 8.7 8.8e-15 55.1 6.1 4.7 3 3 0 4 4 4 1 PAPA-1-like conserved region DUF2249 PF10006.4 ETS65056.1 - 0.35 10.4 1.8 58 3.3 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2249) HUN PF08729.5 ETS65058.1 - 1.6e-12 47.0 1.4 1.6e-12 47.0 1.0 2.6 2 0 0 2 2 2 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 ETS65058.1 - 1.7e-08 34.4 0.8 1.7e-08 34.4 0.6 1.6 2 0 0 2 2 2 1 Ubinuclein conserved middle domain NOA36 PF06524.7 ETS65058.1 - 8 5.6 14.5 16 4.6 10.0 1.5 1 0 0 1 1 1 0 NOA36 protein DUF815 PF05673.8 ETS65059.1 - 0.012 14.6 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 ETS65059.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain NMD3 PF04981.8 ETS65060.1 - 1.7e-80 269.5 3.0 1.7e-80 269.5 2.1 1.5 2 0 0 2 2 2 1 NMD3 family DZR PF12773.2 ETS65060.1 - 0.0058 16.4 5.8 0.13 12.1 3.4 2.7 2 1 1 3 3 3 2 Double zinc ribbon zf-C3HC4_3 PF13920.1 ETS65060.1 - 2 8.1 5.9 0.32 10.7 0.4 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Whi5 PF08528.6 ETS65062.1 - 2.8e-11 42.7 0.0 5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Whi5 like TRAPP PF04051.11 ETS65063.1 - 2e-36 124.8 0.0 2.8e-36 124.3 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Haemagg_act PF05860.8 ETS65063.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 haemagglutination activity domain dsDNA_bind PF01984.15 ETS65064.1 - 3.9e-30 104.0 0.3 5.4e-30 103.5 0.2 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Steroid_dh PF02544.11 ETS65065.1 - 2.4e-25 89.0 5.1 4.7e-19 68.6 3.8 4.4 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 ETS65065.1 - 0.0003 20.1 0.2 0.00049 19.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) JmjC PF02373.17 ETS65066.1 - 4.6e-15 55.8 0.0 1.1e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 ETS65066.1 - 7.6e-05 22.3 0.0 0.057 12.9 0.0 2.5 2 0 0 2 2 2 2 Cupin-like domain DZR PF12773.2 ETS65066.1 - 0.012 15.3 7.3 0.2 11.5 0.2 3.1 3 0 0 3 3 3 0 Double zinc ribbon zf-AN1 PF01428.11 ETS65066.1 - 0.18 11.6 7.3 0.55 10.1 5.1 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger zf-B_box PF00643.19 ETS65066.1 - 0.31 10.9 9.6 0.95 9.4 6.7 1.8 1 0 0 1 1 1 0 B-box zinc finger Maf1 PF09174.5 ETS65069.1 - 2.4e-33 115.4 0.0 2.9e-27 95.6 0.0 2.4 2 0 0 2 2 2 2 Maf1 regulator TruD PF01142.13 ETS65070.1 - 1.2e-57 195.3 0.0 1.3e-54 185.2 0.0 4.5 3 1 0 3 3 3 1 tRNA pseudouridine synthase D (TruD) Pinin_SDK_N PF04697.8 ETS65070.1 - 2.6 8.0 11.2 0.19 11.7 2.7 2.6 2 0 0 2 2 2 0 pinin/SDK conserved region OPT PF03169.10 ETS65071.1 - 7.2e-155 516.9 47.9 8.3e-155 516.7 33.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FA_hydroxylase PF04116.8 ETS65072.1 - 2.8e-15 56.6 13.1 2.8e-15 56.6 9.1 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Thioredoxin_8 PF13905.1 ETS65072.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Glyco_hydro_3 PF00933.16 ETS65073.1 - 7.5e-80 268.1 0.0 1.2e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS65073.1 - 1e-50 172.3 1.0 2.1e-50 171.3 0.7 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS65073.1 - 6.2e-19 67.7 0.0 1.4e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PGAP1 PF07819.8 ETS65074.1 - 4.8e-56 189.8 0.0 6.9e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 ETS65074.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CcoS PF03597.10 ETS65074.1 - 7.1 6.1 10.1 18 4.8 1.1 3.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Abhydrolase_3 PF07859.8 ETS65082.1 - 4.6e-18 65.5 0.6 2.4e-16 59.9 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS65082.1 - 5e-10 38.5 0.0 1.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS65082.1 - 0.00012 21.8 0.5 0.00035 20.3 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS65082.1 - 0.094 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3605 PF12239.3 ETS65083.1 - 4.4e-21 75.3 0.0 6.4e-06 26.0 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) GMC_oxred_N PF00732.14 ETS65084.1 - 2.9e-57 194.1 0.0 3.7e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS65084.1 - 4.6e-32 111.3 0.5 1.2e-31 109.9 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS65084.1 - 1.2e-05 24.4 1.1 0.00036 19.5 1.8 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 ETS65084.1 - 2.1e-05 24.4 1.0 8.2e-05 22.5 0.7 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS65084.1 - 4.3e-05 22.5 0.1 0.00011 21.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS65084.1 - 0.00028 21.0 2.4 0.013 15.5 0.9 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS65084.1 - 0.0016 17.4 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 ETS65084.1 - 0.0021 17.2 0.4 0.004 16.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 ETS65084.1 - 0.016 15.0 1.9 0.043 13.6 1.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS65084.1 - 0.1 11.0 1.3 0.14 10.6 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein Solute_trans_a PF03619.11 ETS65085.1 - 1.6e-72 244.1 22.7 2e-72 243.7 15.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.6 ETS65085.1 - 8.4 6.3 11.4 0.097 12.5 2.0 2.1 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Zn_clus PF00172.13 ETS65086.1 - 9.9e-06 25.3 8.0 1.9e-05 24.4 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrB PF12344.3 ETS65086.1 - 0.1 12.1 0.8 0.23 10.9 0.5 1.6 1 0 0 1 1 1 0 Ultra-violet resistance protein B Aldedh PF00171.17 ETS65087.1 - 5.6e-130 433.7 1.6 6.9e-130 433.4 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS65087.1 - 0.00015 20.6 0.0 0.00022 20.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HORMA PF02301.13 ETS65088.1 - 2e-39 135.2 0.0 2.2e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Potex_coat PF06184.6 ETS65088.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Potexvirus coat protein His_Phos_1 PF00300.17 ETS65089.1 - 6.2e-18 65.3 0.0 1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GMP_synt_C PF00958.17 ETS65090.1 - 5e-40 135.1 0.0 1.1e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 ETS65090.1 - 2.3e-37 128.3 0.0 4.5e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 ETS65090.1 - 5.9e-12 45.0 0.1 1.4e-07 30.6 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 ETS65090.1 - 5.4e-10 39.0 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 ETS65090.1 - 6.1e-05 21.7 0.2 0.00011 20.8 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 ETS65090.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 ETS65090.1 - 0.00081 18.5 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 ETS65090.1 - 0.00095 18.7 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 ETS65090.1 - 0.0012 18.2 0.0 0.0077 15.5 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 ETS65090.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HOASN PF14515.1 ETS65090.1 - 0.065 13.6 0.7 0.16 12.3 0.2 1.8 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices DUF2392 PF10288.4 ETS65090.1 - 0.087 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 ETS65090.1 - 0.14 11.6 0.3 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 PP-loop family IF3_C PF00707.17 ETS65091.1 - 0.00024 20.7 0.1 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 ETS65091.1 - 0.0028 17.0 0.8 0.0054 16.1 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial translation initiation factor ATP-synt_E_2 PF08112.6 ETS65091.1 - 0.082 12.9 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 ATP synthase epsilon subunit WD40 PF00400.27 ETS65092.1 - 9.7e-21 72.8 6.1 1.8e-06 27.6 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETS65092.1 - 0.0042 15.8 0.0 0.01 14.5 0.0 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Cys_Met_Meta_PP PF01053.15 ETS65093.1 - 2.2e-20 72.2 0.0 4.6e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETS65093.1 - 0.0032 16.4 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II FliX PF10768.4 ETS65094.1 - 0.048 13.8 4.0 0.16 12.2 2.8 1.9 1 0 0 1 1 1 0 Class II flagellar assembly regulator ParA PF10609.4 ETS65095.1 - 2.2e-34 117.1 0.1 4.3e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETS65095.1 - 3.3e-10 39.7 0.4 0.00027 20.4 0.2 2.3 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 ETS65095.1 - 4.2e-05 22.7 0.3 0.003 16.6 0.5 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 ETS65095.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS65095.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 VirE PF05272.6 ETS65095.1 - 0.18 11.2 0.1 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E NB-ARC PF00931.17 ETS65095.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC2_membrane PF01061.19 ETS65096.1 - 4e-79 264.6 68.1 2.8e-42 144.2 18.3 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 ETS65096.1 - 1.7e-35 122.3 0.0 1.3e-16 61.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS65096.1 - 2.4e-34 117.1 1.3 1.9e-31 107.7 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 ETS65096.1 - 6.8e-12 45.3 0.2 3.9e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 ETS65096.1 - 6.3e-07 28.9 0.1 0.00072 19.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS65096.1 - 1.7e-05 24.0 0.1 6.7e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS65096.1 - 0.00011 22.4 0.0 0.031 14.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETS65096.1 - 0.00026 20.6 0.3 0.095 12.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 ETS65096.1 - 0.00035 20.6 0.3 0.0067 16.4 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_19 PF13245.1 ETS65096.1 - 0.0024 17.5 1.0 1.3 8.7 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_29 PF13555.1 ETS65096.1 - 0.0036 16.8 0.4 0.017 14.6 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 ETS65096.1 - 0.0053 16.4 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ABC2_membrane_3 PF12698.2 ETS65096.1 - 0.0091 15.0 60.2 0.32 9.9 18.3 4.4 3 2 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 ETS65096.1 - 0.013 15.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 ETS65096.1 - 0.022 14.2 0.9 0.14 11.6 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 ETS65096.1 - 0.029 13.8 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 ETS65096.1 - 0.049 14.4 0.0 0.68 10.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain SMC_N PF02463.14 ETS65096.1 - 0.05 12.8 0.1 2.4 7.3 0.0 3.1 3 1 1 4 4 4 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 ETS65096.1 - 0.057 13.9 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 ETS65096.1 - 0.057 13.6 0.1 3 8.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETS65096.1 - 0.19 12.0 0.5 0.54 10.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 ETS65096.1 - 2 8.7 3.7 1 9.6 0.1 2.3 3 0 0 3 3 2 0 AAA domain NAD_binding_4 PF07993.7 ETS65097.1 - 2e-13 49.8 0.1 1.2e-11 44.0 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETS65097.1 - 9.1e-13 48.1 0.1 2.6e-12 46.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS65097.1 - 1.1e-10 40.6 0.0 3e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 ETS65097.1 - 0.038 13.6 1.1 0.25 10.9 0.5 2.3 2 1 0 2 2 2 0 KR domain NmrA PF05368.8 ETS65097.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.14 ETS65098.1 - 1.8e-39 134.6 0.0 1.7e-38 131.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS65098.1 - 3.6e-26 91.2 0.0 8.6e-26 89.9 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 ETS65098.1 - 5e-05 23.6 0.0 0.00014 22.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 ETS65098.1 - 0.0009 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Mito_carr PF00153.22 ETS65099.1 - 2.5e-55 184.1 6.7 2.1e-20 72.2 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein Gly-zipper_OmpA PF13436.1 ETS65099.1 - 0.023 14.3 3.1 0.023 14.3 2.2 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF389 PF04087.9 ETS65099.1 - 0.072 13.0 1.2 0.23 11.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF389) TPR_2 PF07719.12 ETS65100.1 - 9.7e-27 90.7 19.4 0.00055 19.6 0.1 9.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETS65100.1 - 7.7e-24 83.1 15.5 2.2e-09 36.8 0.0 7.6 4 1 4 9 9 9 7 TPR repeat TPR_1 PF00515.23 ETS65100.1 - 6.6e-23 79.3 1.5 0.00041 19.8 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 ETS65100.1 - 3.5e-19 68.7 11.3 9e-09 35.3 1.1 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETS65100.1 - 1.1e-12 47.6 19.3 2.8e-05 23.9 0.0 7.3 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETS65100.1 - 7.3e-10 37.9 0.0 0.42 10.4 0.0 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS65100.1 - 3.9e-09 36.9 42.0 2e-07 31.5 0.7 7.3 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETS65100.1 - 4.4e-08 32.7 0.8 0.68 10.2 0.0 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS65100.1 - 5e-08 32.8 38.4 0.03 14.9 0.5 9.3 6 4 4 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 ETS65100.1 - 4.8e-06 26.3 21.8 0.023 14.5 0.1 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETS65100.1 - 3e-05 24.1 17.2 0.34 11.4 0.0 8.9 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS65100.1 - 4e-05 23.8 21.4 0.032 14.5 0.2 7.3 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS65100.1 - 0.0011 18.8 20.9 8.3 6.4 0.4 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS65100.1 - 0.019 14.7 17.6 0.16 11.8 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS65100.1 - 3.4 7.6 10.8 64 3.5 0.0 5.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat F-box PF00646.28 ETS65101.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain TOM13 PF08219.6 ETS65102.1 - 2.3e-10 40.0 0.0 5.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF4462 PF14692.1 ETS65102.1 - 0.087 12.0 1.1 0.16 11.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) E1-E2_ATPase PF00122.15 ETS65103.1 - 2.2e-25 89.0 0.0 2.1e-24 85.8 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 ETS65103.1 - 3.5e-23 82.7 0.0 9.3e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS65103.1 - 4e-16 60.0 0.2 6e-14 52.9 0.0 3.5 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS65103.1 - 5.3e-08 32.7 0.0 1.7e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit P5-ATPase PF12409.3 ETS65103.1 - 7.5e-06 25.8 0.1 3.2e-05 23.7 0.0 2.2 3 0 0 3 3 3 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.21 ETS65103.1 - 2.9e-05 23.4 0.0 8.9e-05 21.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Tautomerase PF01361.16 ETS65103.1 - 0.094 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Tautomerase enzyme Glyco_hydro_15 PF00723.16 ETS65104.1 - 1.2e-82 277.9 2.1 1.7e-82 277.4 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Abhydrolase_6 PF12697.2 ETS65105.1 - 2.2e-31 109.4 0.1 3.7e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS65105.1 - 5.4e-11 42.4 0.0 1.3e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS65105.1 - 8.5e-09 35.3 0.0 0.0085 15.6 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 ETS65105.1 - 0.0012 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 ETS65105.1 - 0.0018 18.0 0.0 0.0051 16.6 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Rad60-SLD_2 PF13881.1 ETS65106.1 - 7.8e-14 51.5 0.0 1.9e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.27 ETS65107.1 - 3.1e-27 93.4 1.0 1.5e-07 30.9 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Helicase_C_3 PF13625.1 ETS65108.1 - 9e-28 96.6 0.0 2.3e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS65108.1 - 6.8e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS65108.1 - 6.9e-13 48.0 0.1 1.2e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS65108.1 - 6.9e-10 38.6 0.1 1.7e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS65108.1 - 1e-07 31.5 0.7 2.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ras PF00071.17 ETS65109.1 - 4.9e-31 107.3 0.0 5.4e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS65109.1 - 2.4e-06 28.0 0.0 3.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETS65109.1 - 0.025 14.0 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain UQ_con PF00179.21 ETS65110.1 - 2.4e-24 85.3 0.0 3.2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_3 PF07859.8 ETS65111.1 - 1.8e-23 83.2 0.0 3.7e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS65111.1 - 5.1e-06 26.3 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS65111.1 - 0.00015 20.4 0.0 0.00024 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF1168 PF06658.7 ETS65112.1 - 2.5e-40 137.2 17.9 3.5e-40 136.8 12.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) CPSF100_C PF13299.1 ETS65112.1 - 0.39 10.8 5.1 0.61 10.2 3.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.2 ETS65112.1 - 4.4 4.8 11.6 4.4 4.8 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 ETS65112.1 - 4.8 7.1 16.2 8.1 6.4 11.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Vps16_C PF04840.7 ETS65113.1 - 2.4e-70 237.0 4.2 6.1e-47 160.1 1.9 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.8 ETS65113.1 - 1.7e-68 231.0 0.0 3.8e-42 144.2 0.0 3.3 3 0 0 3 3 3 3 Vps16, N-terminal region WLM PF08325.5 ETS65114.1 - 7.8e-48 162.8 8.2 2.7e-47 161.0 1.9 2.8 2 1 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 ETS65114.1 - 7.6e-06 24.9 3.2 1.4e-05 24.0 2.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 ETS65114.1 - 0.016 15.0 2.3 0.019 14.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF2509 PF10713.4 ETS65114.1 - 0.041 13.6 1.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) DUF3519 PF12033.3 ETS65114.1 - 0.092 12.9 0.4 0.29 11.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) Ebola_NP PF05505.7 ETS65114.1 - 0.55 8.2 6.3 0.72 7.8 4.4 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein GATA PF00320.22 ETS65116.1 - 5.1e-12 44.9 2.4 1.1e-11 43.8 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Sugar_tr PF00083.19 ETS65117.1 - 3.5e-86 289.5 21.1 4.2e-86 289.3 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS65117.1 - 6.8e-21 74.3 18.5 6.8e-21 74.3 12.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily GST_N PF02798.15 ETS65118.1 - 7.4e-13 48.4 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS65118.1 - 1.1e-11 44.8 0.0 2.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS65118.1 - 2.4e-11 43.4 0.0 5.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3028 PF11229.3 ETS65118.1 - 0.12 10.5 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) Ribosomal_L5_C PF00673.16 ETS65119.1 - 3.7e-22 77.8 0.0 5.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 ETS65119.1 - 2.8e-17 62.2 0.1 5.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 DEAD PF00270.24 ETS65121.1 - 1.3e-43 148.4 0.0 1.4e-42 145.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS65121.1 - 9.3e-28 95.9 0.1 1.7e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS65121.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 ETS65121.1 - 0.045 12.1 0.0 0.076 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) AMP-binding PF00501.23 ETS65122.1 - 6.7e-35 120.2 0.1 2.2e-34 118.5 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS65122.1 - 1.3e-33 115.9 0.0 3.6e-33 114.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 ETS65122.1 - 1e-07 32.1 0.0 4.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 ETS65122.1 - 1.4e-07 31.2 0.0 9.1e-07 28.5 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS65122.1 - 0.00095 19.1 2.1 0.0035 17.2 0.1 2.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS65122.1 - 0.0025 17.5 1.9 0.0075 15.9 0.1 2.6 2 0 0 2 2 2 1 KR domain AraC_binding_2 PF14525.1 ETS65122.1 - 0.0094 15.5 1.7 2.1 7.8 0.2 2.6 2 0 0 2 2 2 2 AraC-binding-like domain 3Beta_HSD PF01073.14 ETS65122.1 - 0.014 14.0 0.1 0.086 11.5 0.1 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS65122.1 - 0.088 11.6 0.1 0.17 10.7 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 ETS65122.1 - 0.32 10.9 1.5 0.79 9.6 0.1 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 ETS65123.1 - 2.4e-27 95.5 21.5 2.4e-27 95.5 14.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2637 PF10935.3 ETS65123.1 - 0.91 9.4 5.8 0.12 12.2 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2637) RPAP1_N PF08621.5 ETS65123.1 - 0.98 9.0 2.2 2.4 7.8 0.2 2.1 2 0 0 2 2 2 0 RPAP1-like, N-terminal Aldo_ket_red PF00248.16 ETS65124.1 - 2.4e-49 167.6 0.0 3.1e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 ETS65124.1 - 8.9e-05 22.1 0.8 0.43 10.3 0.0 2.5 2 0 0 2 2 2 2 Slx4 endonuclease Fungal_trans PF04082.13 ETS65125.1 - 2.7e-18 65.7 0.1 4.7e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 ETS65125.1 - 1.4e-05 25.0 8.5 0.031 14.6 0.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS65125.1 - 0.0013 18.9 18.5 0.008 16.4 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 ETS65125.1 - 0.33 10.6 3.3 9.4 6.0 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ctr PF04145.10 ETS65125.1 - 0.34 10.9 4.3 40 4.2 2.4 3.2 2 0 0 2 2 2 0 Ctr copper transporter family PAT1 PF09770.4 ETS65125.1 - 0.86 7.7 24.2 1.4 7.0 16.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DHHW PF14286.1 ETS65125.1 - 0.89 8.8 3.3 1.5 8.0 2.3 1.3 1 0 0 1 1 1 0 DHHW protein BAF1_ABF1 PF04684.8 ETS65125.1 - 1.6 7.5 21.3 3.8 6.2 14.8 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.10 ETS65125.1 - 9.9 5.3 12.3 22 4.2 8.5 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein adh_short PF00106.20 ETS65129.1 - 1e-12 48.3 7.6 3.1e-12 46.7 5.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS65129.1 - 0.00021 20.9 1.5 0.00033 20.3 0.2 1.8 2 0 0 2 2 2 1 KR domain Nop25 PF09805.4 ETS65130.1 - 2.2e-24 86.0 13.8 2.2e-24 86.0 9.6 3.5 4 0 0 4 4 4 1 Nucleolar protein 12 (25kDa) RRM_6 PF14259.1 ETS65130.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS65130.1 - 0.0014 18.1 0.0 0.0071 15.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_bind_3 PF03067.10 ETS65131.1 - 1.6e-47 162.1 1.3 1.6e-47 162.1 0.9 1.7 2 0 0 2 2 2 1 Chitin binding domain Hex_IIIa PF02455.11 ETS65131.1 - 0.36 9.4 5.9 0.5 8.9 4.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Macoilin PF09726.4 ETS65131.1 - 1.1 7.4 14.7 1.3 7.1 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 ETS65131.1 - 2.1 6.8 8.9 2.7 6.5 6.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CMD PF02627.15 ETS65132.1 - 9.3e-20 70.2 0.1 1.5e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Methyltransf_24 PF13578.1 ETS65133.1 - 2.4e-09 37.9 0.0 4.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_RNA PF04452.9 ETS65133.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Ribosomal_60s PF00428.14 ETS65133.1 - 0.038 14.3 3.9 0.074 13.4 2.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.11 ETS65134.1 - 1.9e-17 62.9 54.9 1.9e-17 62.9 38.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 ETS65134.1 - 8.9 5.8 10.3 15 5.1 0.1 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TPR_12 PF13424.1 ETS65137.1 - 6.1e-12 45.3 21.2 1.3e-05 25.0 0.7 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat AAA_22 PF13401.1 ETS65137.1 - 0.0012 18.9 0.1 0.0081 16.3 0.0 2.5 1 0 0 1 1 1 1 AAA domain TPR_7 PF13176.1 ETS65137.1 - 0.0017 17.9 4.4 2.8 7.9 0.0 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_18 PF13238.1 ETS65137.1 - 0.095 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.1 ETS65137.1 - 0.92 9.5 13.6 0.49 10.4 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS65137.1 - 3.3 7.8 14.4 3.8 7.6 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat UPF0121 PF03661.8 ETS65138.1 - 8.4e-24 84.1 4.2 1.1e-23 83.7 2.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_11 PF13414.1 ETS65139.1 - 4.7e-09 35.7 1.6 1.7e-07 30.7 0.0 3.0 3 0 0 3 3 3 1 TPR repeat DnaJ PF00226.26 ETS65139.1 - 9.4e-06 25.2 0.2 2.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 ETS65139.1 - 0.17 11.8 6.0 8.5 6.5 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat KIAA1328 PF15369.1 ETS65139.1 - 0.48 10.1 8.6 0.036 13.9 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 JmjC PF02373.17 ETS65140.1 - 6.6e-39 132.6 0.1 1.4e-38 131.6 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 ETS65140.1 - 3.2e-15 55.3 0.1 7.4e-15 54.1 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.1 ETS65140.1 - 9.7e-10 38.4 2.6 2.3e-09 37.2 1.8 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETS65140.1 - 1.5e-09 37.8 2.2 4.2e-09 36.4 1.5 1.8 1 1 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.3 ETS65140.1 - 0.17 11.8 1.5 0.39 10.7 1.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain AMP-binding PF00501.23 ETS65141.1 - 4.9e-33 114.1 0.0 6.5e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ATP-synt_J PF04911.7 ETS65142.1 - 6e-24 83.2 0.6 8.3e-24 82.8 0.4 1.2 1 0 0 1 1 1 1 ATP synthase j chain MFS_1 PF07690.11 ETS65143.1 - 1.2e-25 89.9 27.9 1.9e-25 89.3 18.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS65143.1 - 6e-09 34.9 3.2 6e-09 34.9 2.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter SNARE_assoc PF09335.6 ETS65144.1 - 2.2e-13 50.4 1.9 2.2e-13 50.4 1.3 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein Sex_peptide PF08138.6 ETS65144.1 - 0.32 10.8 1.9 23 4.9 0.1 2.7 3 0 0 3 3 3 0 Sex peptide (SP) family Proteasome PF00227.21 ETS65145.1 - 1e-58 197.8 0.2 1.3e-58 197.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS65145.1 - 1.2e-14 53.3 0.1 1.2e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribosomal_L22 PF00237.14 ETS65145.1 - 0.041 13.8 0.8 0.086 12.7 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Ion_trans PF00520.26 ETS65146.1 - 8.4e-102 338.5 68.8 6.1e-36 123.5 2.8 5.2 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 ETS65146.1 - 0.00072 18.0 7.6 0.00072 18.0 5.2 7.0 7 1 1 8 8 8 5 Polycystin cation channel DUF1639 PF07797.9 ETS65146.1 - 8.4 5.8 6.3 28 4.1 4.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) HAD_2 PF13419.1 ETS65147.1 - 7.6e-16 58.8 0.0 1.3e-13 51.5 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS65147.1 - 2.1e-06 27.3 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 ETS65147.1 - 0.00014 22.3 0.0 0.00031 21.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase COX4 PF02936.9 ETS65148.1 - 5.9e-35 120.0 0.1 9.6e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV HlyD PF00529.15 ETS65148.1 - 0.02 14.2 0.1 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein HMG_box_2 PF09011.5 ETS65148.1 - 8.4 6.8 7.8 3.9 7.8 0.1 2.6 2 1 1 3 3 3 0 HMG-box domain SH3BGR PF04908.10 ETS65149.1 - 2e-08 34.0 0.0 6.9e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein PUF PF00806.14 ETS65150.1 - 1.5e-17 62.0 0.0 0.00012 21.3 0.0 5.2 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat MyTH4 PF00784.12 ETS65150.1 - 0.045 13.6 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 MyTH4 domain Ornatin PF02088.10 ETS65150.1 - 0.13 11.8 0.1 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Ornatin RNase_PH PF01138.16 ETS65151.1 - 6.2e-22 78.3 0.1 1.3e-21 77.2 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETS65151.1 - 0.054 13.4 0.0 0.3 11.0 0.0 2.3 2 1 0 2 2 2 0 3' exoribonuclease family, domain 2 COG7 PF10191.4 ETS65152.1 - 1.2e-39 135.9 13.7 3.2e-36 124.6 8.5 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) MOFRL PF05161.8 ETS65152.1 - 0.12 12.5 0.1 0.51 10.4 0.1 2.1 1 0 0 1 1 1 0 MOFRL family CDC37_N PF03234.9 ETS65153.1 - 5.1e-52 176.7 3.8 5.1e-52 176.7 2.7 2.1 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 ETS65153.1 - 3.6e-28 98.2 0.3 1.4e-22 79.9 0.0 2.4 2 0 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 ETS65153.1 - 2.1e-22 78.8 0.4 8.3e-22 76.9 0.2 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain Fe-S_biosyn PF01521.15 ETS65153.1 - 2e-13 50.2 0.0 5.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HTH_22 PF13309.1 ETS65153.1 - 0.053 13.2 0.7 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 HTH domain Adeno_VII PF03228.9 ETS65153.1 - 0.24 11.9 3.8 0.68 10.5 0.0 3.3 4 0 0 4 4 4 0 Adenoviral core protein VII NAC PF01849.13 ETS65154.1 - 7.2e-21 73.4 0.0 1.4e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 ETS65154.1 - 0.00047 19.9 0.1 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF399 PF04187.8 ETS65154.1 - 0.027 13.9 2.0 0.04 13.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF399 YbaB_DNA_bd PF02575.11 ETS65154.1 - 1.7 8.5 12.1 0.92 9.4 6.4 1.9 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family PMT PF02366.13 ETS65156.1 - 1.8e-69 233.8 18.0 1.8e-69 233.8 12.5 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 ETS65156.1 - 2.4e-25 89.2 4.0 6e-25 87.8 2.7 1.7 1 1 0 1 1 1 1 MIR domain GET2 PF08690.5 ETS65157.1 - 0.012 14.8 7.2 0.81 8.8 0.4 2.9 2 2 0 2 2 2 0 GET complex subunit GET2 Hid1 PF12722.2 ETS65158.1 - 1.9e-118 396.5 0.0 8.6e-104 348.0 0.0 3.8 2 1 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 ETS65158.1 - 9.1e-56 189.3 0.0 6.8e-54 183.1 0.0 2.2 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Inhibitor_G39P PF11417.3 ETS65158.1 - 0.092 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P BSD PF03909.12 ETS65159.1 - 2.1e-20 72.2 0.1 1.4e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 ETS65159.1 - 3.3e-16 58.6 0.1 8.1e-16 57.4 0.1 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Mucin PF01456.12 ETS65159.1 - 1.3 8.7 16.7 0.2 11.4 6.3 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein DSPc PF00782.15 ETS65160.1 - 1.1e-07 31.5 0.0 3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS65160.1 - 0.0024 17.2 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 ETS65160.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 ETS65160.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-C3HC4_3 PF13920.1 ETS65161.1 - 3.5e-06 26.6 6.0 3.5e-06 26.6 4.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS65161.1 - 1.3 8.7 17.8 0.04 13.5 6.1 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 ETS65162.1 - 1.5e-43 148.1 0.5 1.5e-43 148.1 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS65162.1 - 2.1e-24 85.1 0.6 2.4e-23 81.7 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 ETS65162.1 - 0.00026 20.6 0.2 0.00077 19.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 ETS65162.1 - 0.001 18.9 0.0 0.002 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 ETS65162.1 - 0.022 14.3 0.1 0.064 12.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 ETS65162.1 - 0.023 13.7 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 ETS65162.1 - 0.057 13.5 0.2 0.19 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 ETS65162.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Helicase Zn_clus PF00172.13 ETS65163.1 - 1.9e-09 37.2 8.0 3.4e-09 36.4 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dabb PF07876.7 ETS65164.1 - 3.6e-14 52.9 0.0 4e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain SNF2_N PF00176.18 ETS65165.1 - 4.9e-61 206.1 0.0 8.9e-61 205.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS65165.1 - 1.4e-15 56.9 0.0 4.2e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 ETS65165.1 - 6.2e-13 48.3 8.8 6.2e-13 48.3 6.1 3.0 3 0 0 3 3 3 1 HSA HDA2-3 PF11496.3 ETS65165.1 - 0.049 12.4 0.1 7.8 5.2 0.0 2.5 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 HLH PF00010.21 ETS65166.1 - 2.2e-12 46.4 0.0 6e-12 45.0 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AMP-binding_C PF13193.1 ETS65166.1 - 2.3e-05 25.2 0.0 4.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIIA PF03153.8 ETS65166.1 - 0.21 11.4 6.1 0.34 10.7 4.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tom22 PF04281.8 ETS65166.1 - 1.5 8.3 9.4 6.8 6.2 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF423 PF04241.10 ETS65167.1 - 1.7e-25 88.7 2.9 2.7e-25 88.1 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Tyrosinase PF00264.15 ETS65168.1 - 4.9e-21 75.9 5.2 8.8e-21 75.0 3.6 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF866 PF05907.8 ETS65169.1 - 1.6e-42 144.7 0.0 1.8e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-CHY PF05495.7 ETS65169.1 - 0.0063 16.6 0.5 0.012 15.7 0.4 1.3 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C7 PF14522.1 ETS65169.1 - 0.007 15.9 0.9 0.012 15.2 0.6 1.4 1 0 0 1 1 1 1 Cytochrome c7 Ribosomal_L44 PF00935.14 ETS65169.1 - 0.05 13.6 0.7 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L44 Cytochrome_C554 PF13435.1 ETS65169.1 - 0.081 12.9 2.6 0.18 11.8 1.8 1.6 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 ETS65169.1 - 0.28 11.5 4.0 1.5 9.1 1.9 1.9 1 1 0 1 1 1 0 Cytochrome c3 Sec15 PF04091.7 ETS65170.1 - 2.1e-79 267.0 0.0 6.6e-79 265.4 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 ETS65170.1 - 4.9e-05 23.1 0.2 0.00014 21.6 0.1 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 ETS65170.1 - 8.4e-05 22.2 1.8 0.00015 21.4 0.3 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG5 PF10392.4 ETS65170.1 - 0.0005 20.0 1.2 0.002 18.0 0.2 2.6 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 ETS65170.1 - 0.0043 16.8 0.0 0.018 14.8 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DPBB_1 PF03330.13 ETS65171.1 - 2.6e-06 27.3 0.0 9.8e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 ETS65171.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Barwin family MIP-T3 PF10243.4 ETS65171.1 - 0.055 11.9 20.0 0.093 11.1 13.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Totivirus_coat PF05518.6 ETS65171.1 - 0.23 9.2 8.4 0.33 8.7 5.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mitofilin PF09731.4 ETS65171.1 - 0.28 9.7 15.8 0.38 9.3 10.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAT1 PF09770.4 ETS65171.1 - 4.5 5.3 40.8 5.5 5.1 28.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cys_Met_Meta_PP PF01053.15 ETS65172.1 - 1.9e-120 401.7 0.0 2.6e-120 401.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 ETS65172.1 - 7.8e-19 67.5 2.5 4.6e-18 65.0 1.9 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS65172.1 - 3.2e-07 30.4 1.0 1.2e-06 28.5 0.1 2.3 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 ETS65172.1 - 0.006 15.8 0.1 0.015 14.5 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature NTF2 PF02136.15 ETS65173.1 - 3.6e-08 33.7 0.2 6.1e-07 29.8 0.0 2.5 3 0 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 ETS65173.1 - 3.7e-08 33.3 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 RNR_inhib PF08591.5 ETS65174.1 - 0.00073 20.4 2.4 0.0013 19.5 0.8 2.2 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor Oxysterol_BP PF01237.13 ETS65175.1 - 5.2e-91 304.7 0.0 6.9e-91 304.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Phage_stabilise PF11134.3 ETS65175.1 - 0.009 14.6 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 1 Phage stabilisation protein DUF1676 PF07898.8 ETS65176.1 - 0.0067 16.7 3.2 0.018 15.2 2.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) PBP1_TM PF14812.1 ETS65176.1 - 9.9 6.5 11.2 5.3 7.4 0.1 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_1 PF00515.23 ETS65177.1 - 1.1e-56 186.2 27.4 2.7e-08 33.0 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETS65177.1 - 1.9e-51 167.8 23.1 5.1e-06 25.9 0.0 10.8 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 ETS65177.1 - 1.4e-49 165.5 40.5 6.9e-13 48.0 3.5 6.6 3 2 5 8 8 8 8 TPR repeat TPR_8 PF13181.1 ETS65177.1 - 1.8e-35 118.0 15.2 0.00013 21.4 2.4 10.4 7 2 3 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 ETS65177.1 - 2.3e-30 102.2 19.4 9.2e-05 22.3 0.3 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETS65177.1 - 4.4e-30 101.0 5.4 0.0028 17.3 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 ETS65177.1 - 6.3e-30 102.9 18.8 5.4e-07 29.4 0.0 6.7 1 1 5 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETS65177.1 - 1.5e-29 99.7 21.1 0.00034 20.9 0.0 10.7 4 3 7 11 11 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETS65177.1 - 5.9e-28 96.9 44.4 9.3e-08 32.5 0.5 9.1 5 2 4 9 9 8 7 Tetratricopeptide repeat TPR_6 PF13174.1 ETS65177.1 - 6.2e-24 82.7 11.9 0.0011 19.2 0.0 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS65177.1 - 5.9e-22 77.7 23.4 1.9e-06 28.0 0.2 7.1 4 2 5 9 9 8 7 Tetratricopeptide repeat TPR_9 PF13371.1 ETS65177.1 - 4.9e-16 58.3 11.7 0.0062 16.3 0.0 6.3 1 1 6 8 8 8 7 Tetratricopeptide repeat Apc3 PF12895.2 ETS65177.1 - 4.2e-13 49.2 9.3 7.1e-07 29.2 1.3 4.7 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 ETS65177.1 - 6.6e-09 35.2 10.8 0.0022 17.1 1.3 5.1 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 ETS65177.1 - 0.001 19.1 3.4 0.014 15.4 0.1 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETS65177.1 - 0.0055 16.1 4.2 0.49 9.8 1.1 2.9 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TOM20_plant PF06552.7 ETS65177.1 - 0.0087 15.6 1.3 6.1 6.3 0.2 3.7 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 ChAPs PF09295.5 ETS65177.1 - 0.0096 14.7 1.0 1.1 7.9 0.1 2.7 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 ETS65177.1 - 0.036 14.0 18.2 1.6 8.7 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 ETS65177.1 - 0.083 12.7 0.3 15 5.4 0.0 3.6 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.1 ETS65177.1 - 0.39 10.6 12.3 37 4.3 0.0 6.0 5 2 2 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat adh_short_C2 PF13561.1 ETS65178.1 - 4.6e-28 98.5 0.0 5.9e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS65178.1 - 3e-24 85.7 0.0 3.9e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS65178.1 - 1.6e-09 37.7 0.0 2.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 KR domain TraK PF06586.6 ETS65178.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 TraK protein DUF4523 PF15023.1 ETS65178.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) TPT PF03151.11 ETS65179.1 - 6.2e-31 107.1 4.9 6.2e-31 107.1 3.4 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 ETS65179.1 - 6e-10 39.2 25.0 2.2e-05 24.4 5.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 ETS65179.1 - 6.6e-05 21.9 16.0 0.00079 18.4 11.1 2.2 1 1 0 1 1 1 1 UAA transporter family eIF3_subunit PF08597.5 ETS65179.1 - 0.34 10.4 5.6 0.62 9.5 3.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Med31 PF05669.7 ETS65180.1 - 1.8e-28 98.2 0.1 2.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 SOH1 GSH_synth_ATP PF03917.12 ETS65181.1 - 2e-99 332.7 0.0 2.4e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 ETS65181.1 - 1.7e-32 111.5 0.0 3.1e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Peptidase_M85 PF13678.1 ETS65181.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease V-ATPase_H_N PF03224.9 ETS65182.1 - 4.6e-102 341.3 0.0 8.2e-102 340.5 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 ETS65182.1 - 2.4e-40 137.1 0.0 6.3e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.18 ETS65182.1 - 0.0031 17.2 5.7 0.38 10.6 0.2 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS65182.1 - 0.019 15.2 0.3 0.16 12.2 0.0 2.7 3 1 1 4 4 4 0 HEAT repeats Ipi1_N PF12333.3 ETS65182.1 - 0.02 14.8 0.1 1.7 8.6 0.0 3.4 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Synthase_beta PF11421.3 ETS65182.1 - 0.032 14.8 3.9 0.032 14.8 2.7 2.6 2 0 0 2 2 2 0 ATP synthase F1 beta subunit HEAT PF02985.17 ETS65182.1 - 0.082 13.0 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Sporozoite_P67 PF05642.6 ETS65182.1 - 0.35 8.6 3.8 0.66 7.7 2.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MRP-L46 PF11788.3 ETS65183.1 - 3.2e-24 85.7 0.4 6.2e-24 84.7 0.3 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 GTP_EFTU PF00009.22 ETS65183.1 - 8.4e-24 84.0 0.0 1.8e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS65183.1 - 3.7e-09 36.6 0.0 9.3e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS65183.1 - 3.9e-06 26.8 0.9 1e-05 25.5 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 ETS65183.1 - 5.9e-05 22.6 2.5 9.9e-05 21.9 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 NUDIX PF00293.23 ETS65183.1 - 0.047 13.3 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain MMR_HSR1 PF01926.18 ETS65183.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 ETS65183.1 - 0.55 10.7 2.1 6.7 7.2 0.3 3.1 2 1 0 2 2 2 0 Miro-like protein Nop52 PF05997.7 ETS65184.1 - 8.4e-71 237.8 0.0 1.4e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 ETS65184.1 - 0.1 11.8 0.0 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF2146 PF10220.4 ETS65184.1 - 0.23 9.4 6.6 0.33 8.8 4.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SGT1 PF07093.6 ETS65184.1 - 0.28 9.5 15.9 0.41 8.9 11.0 1.2 1 0 0 1 1 1 0 SGT1 protein Actin PF00022.14 ETS65185.1 - 2.1e-53 181.1 0.0 5.3e-26 90.9 0.0 2.3 2 0 0 2 2 2 2 Actin LMBR1 PF04791.11 ETS65185.1 - 1 7.8 6.2 2.4 6.6 0.6 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein ATG16 PF08614.6 ETS65186.1 - 1.1e-61 208.0 17.1 1.7e-61 207.4 11.9 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 ETS65186.1 - 0.085 12.7 1.2 13 5.7 0.2 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-H PF05837.7 ETS65186.1 - 0.19 11.9 17.8 0.58 10.3 1.4 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF3138 PF11336.3 ETS65186.1 - 0.9 7.6 8.9 0.065 11.4 2.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) IncA PF04156.9 ETS65186.1 - 1.4 8.4 22.5 1.6 8.3 14.3 2.0 1 1 0 1 1 1 0 IncA protein DASH_Dam1 PF08653.5 ETS65186.1 - 1.4 8.6 3.8 19 5.0 0.2 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4094 PF13334.1 ETS65186.1 - 2.4 8.5 5.9 3.3 8.1 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF972 PF06156.8 ETS65186.1 - 2.4 8.5 15.1 0.84 10.0 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 ETS65186.1 - 4 7.1 24.1 0.22 11.2 6.1 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Lectin_N PF03954.9 ETS65186.1 - 6.9 6.0 9.7 0.58 9.5 1.6 2.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain USP8_interact PF08941.5 ETS65186.1 - 9.8 5.4 7.6 0.5 9.6 0.9 2.0 2 0 0 2 2 2 0 USP8 interacting Ras PF00071.17 ETS65187.1 - 1.2e-56 190.5 0.0 1.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS65187.1 - 8.8e-18 64.9 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS65187.1 - 2.5e-12 46.3 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS65187.1 - 1.6e-06 28.0 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETS65187.1 - 1.9e-05 23.9 0.0 2.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS65187.1 - 3.7e-05 23.2 0.0 0.00071 19.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 ETS65187.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETS65187.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 ETS65187.1 - 0.0032 16.9 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 ETS65187.1 - 0.0038 16.2 0.1 0.053 12.5 0.0 2.2 2 1 0 2 2 2 1 Septin AAA_16 PF13191.1 ETS65187.1 - 0.0052 16.7 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 ETS65187.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS65187.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 ETS65187.1 - 0.0086 15.5 0.0 0.029 13.8 0.0 1.7 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 ETS65187.1 - 0.0096 15.4 0.3 0.6 9.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 ETS65187.1 - 0.011 15.5 0.0 0.06 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 ETS65187.1 - 0.013 14.9 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 ETS65187.1 - 0.02 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 ETS65187.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 ETS65187.1 - 0.035 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 ETS65187.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 ETS65187.1 - 0.097 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Prp19_bind PF06991.6 ETS65188.1 - 8.2e-56 189.2 16.6 8.2e-56 189.2 11.5 3.2 2 1 1 3 3 3 2 Splicing factor, Prp19-binding domain Far-17a_AIG1 PF04750.9 ETS65189.1 - 8.4e-06 25.0 12.2 8.4e-06 25.0 8.5 1.9 2 1 0 2 2 2 1 FAR-17a/AIG1-like protein Zn_clus PF00172.13 ETS65190.1 - 6.4e-05 22.7 8.9 0.00012 21.9 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.22 ETS65191.1 - 1.1e-06 27.9 2.5 1.8e-06 27.1 1.7 1.4 1 0 0 1 1 1 1 GATA zinc finger MCLC PF05934.6 ETS65192.1 - 0.012 14.0 0.9 0.015 13.6 0.6 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Vma12 PF11712.3 ETS65193.1 - 1.5e-29 102.5 0.1 2.6e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF89 PF01937.14 ETS65194.1 - 8.9e-111 370.0 0.0 1.8e-79 267.1 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 HSCB_C PF07743.8 ETS65195.1 - 5.8e-15 55.5 5.3 9.2e-15 54.8 3.7 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 ETS65195.1 - 2.1e-08 33.7 0.0 5.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.2 ETS65195.1 - 0.031 14.1 0.6 0.055 13.2 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon cwf21 PF08312.7 ETS65195.1 - 0.075 12.8 2.8 0.14 11.9 1.9 1.4 1 0 0 1 1 1 0 cwf21 domain Opy2 PF09463.5 ETS65195.1 - 0.46 10.6 3.8 0.85 9.7 2.7 1.3 1 0 0 1 1 1 0 Opy2 protein zf-ribbon_3 PF13248.1 ETS65195.1 - 0.89 8.8 5.5 11 5.3 4.3 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 ETS65195.1 - 6.6 6.7 5.6 4.8 7.2 0.3 2.3 1 1 1 2 2 2 0 Zinc ribbon domain SNARE PF05739.14 ETS65196.1 - 0.031 13.9 0.0 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 SNARE domain DUF2803 PF10972.3 ETS65196.1 - 0.057 12.9 0.4 0.063 12.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) DUF3185 PF11381.3 ETS65196.1 - 0.075 12.7 0.1 0.44 10.3 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) Ribosomal_L16 PF00252.13 ETS65197.1 - 6.6e-41 139.1 0.2 8.2e-41 138.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Sec20 PF03908.8 ETS65198.1 - 1.1e-16 60.3 1.7 1.1e-16 60.3 1.1 2.6 3 0 0 3 3 3 1 Sec20 Syntaxin-6_N PF09177.6 ETS65198.1 - 0.4 11.0 11.3 1.7 9.0 1.0 4.0 3 2 0 3 3 3 0 Syntaxin 6, N-terminal DUF4064 PF13273.1 ETS65198.1 - 0.99 9.5 6.3 1.8 8.7 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF1045 PF06299.7 ETS65198.1 - 2.6 7.6 7.4 3.1 7.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) ATP-synt_B PF00430.13 ETS65198.1 - 6.7 6.5 19.0 0.36 10.6 3.4 2.7 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) EmrE PF13536.1 ETS65199.1 - 6.6e-08 32.7 4.1 6.6e-08 32.7 2.9 2.8 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 ETS65199.1 - 7.5e-08 32.4 34.5 1.5e-07 31.5 4.3 3.0 3 0 0 3 3 3 2 EamA-like transporter family Glyco_hydro_cc PF11790.3 ETS65200.1 - 2.8e-59 200.4 6.6 3.5e-59 200.1 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.12 ETS65200.1 - 0.011 14.1 0.1 0.062 11.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 39 LAM_C PF12544.3 ETS65200.1 - 0.038 14.0 0.3 0.038 14.0 0.2 1.6 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Slx4 PF09494.5 ETS65201.1 - 1.1e-15 57.0 0.0 1.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Y_phosphatase2 PF03162.8 ETS65202.1 - 1.9e-41 141.1 0.0 1.1e-40 138.7 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family SelP_N PF04592.9 ETS65202.1 - 3.7 6.8 7.6 5.7 6.2 5.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Chromo PF00385.19 ETS65203.1 - 2.6e-06 27.0 0.2 5.3e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RF-1 PF00472.15 ETS65204.1 - 5e-22 77.8 3.6 9.9e-22 76.8 2.5 1.4 1 0 0 1 1 1 1 RF-1 domain Aminotran_5 PF00266.14 ETS65205.1 - 3.2e-31 108.4 0.0 4.2e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Med7 PF05983.6 ETS65206.1 - 1.3e-43 148.6 0.2 3.1e-43 147.3 0.1 1.6 1 0 0 1 1 1 1 MED7 protein Sel1 PF08238.7 ETS65206.1 - 2.4e-12 47.0 19.5 6.1e-05 23.5 0.1 4.3 4 0 0 4 4 4 3 Sel1 repeat RNA_POL_M_15KD PF02150.11 ETS65207.1 - 8.8e-13 47.7 2.6 8.8e-13 47.7 1.8 3.2 4 0 0 4 4 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 ETS65207.1 - 1.2e-12 47.1 4.4 6.3e-11 41.7 0.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 ETS65207.1 - 0.0011 19.2 2.3 0.0085 16.3 0.0 2.5 2 1 0 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.2 ETS65207.1 - 0.0025 17.6 2.8 0.65 9.8 0.3 3.1 3 0 0 3 3 3 1 Double zinc ribbon Elf1 PF05129.8 ETS65207.1 - 0.003 17.1 1.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like CpXC PF14353.1 ETS65207.1 - 0.0068 16.3 7.1 1.9 8.4 0.1 3.2 1 1 2 3 3 3 2 CpXC protein Zn-ribbon_8 PF09723.5 ETS65207.1 - 0.014 15.3 7.2 11 6.0 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Crust_neurohorm PF01147.12 ETS65207.1 - 0.058 12.7 2.8 0.41 10.0 0.0 2.3 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Zn_Tnp_IS1595 PF12760.2 ETS65207.1 - 0.11 12.2 8.5 1.8 8.4 1.2 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 ETS65207.1 - 0.13 12.3 8.9 0.88 9.6 0.8 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 ETS65207.1 - 0.18 12.0 3.9 1.3 9.2 0.2 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain GFA PF04828.9 ETS65207.1 - 0.28 11.1 4.5 7.2 6.6 0.1 2.8 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 ETS65207.1 - 0.35 10.1 9.2 1.6 7.9 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 ETS65207.1 - 0.66 9.7 4.0 0.8 9.4 0.3 2.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH_5 PF14279.1 ETS65207.1 - 0.72 9.9 3.8 19 5.3 1.2 2.8 2 1 0 2 2 2 0 HNH endonuclease PHD PF00628.24 ETS65207.1 - 0.72 9.5 7.1 0.72 9.5 0.1 2.7 2 1 0 2 2 2 0 PHD-finger DNA_RNApol_7kD PF03604.8 ETS65207.1 - 0.74 9.3 10.5 6.3 6.3 0.0 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Rubredoxin PF00301.15 ETS65207.1 - 0.82 9.5 6.6 40 4.1 0.0 3.6 4 0 0 4 4 4 0 Rubredoxin Auto_anti-p27 PF06677.7 ETS65207.1 - 0.86 9.4 0.1 0.86 9.4 0.0 2.9 5 0 0 5 5 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3795 PF12675.2 ETS65207.1 - 1 9.6 4.0 4.7 7.4 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) HypA PF01155.14 ETS65207.1 - 3.3 7.4 6.0 0.33 10.6 0.3 2.2 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-3CxxC PF13695.1 ETS65207.1 - 4.1 7.6 6.8 2.8 8.2 0.8 2.6 1 1 1 2 2 2 0 Zinc-binding domain eIF-5_eIF-2B PF01873.12 ETS65207.1 - 5.1 6.7 6.1 6.1 6.5 0.3 2.5 2 1 1 3 3 3 0 Domain found in IF2B/IF5 zf-TFIIB PF13453.1 ETS65207.1 - 5.4 6.2 8.2 11 5.3 0.3 2.8 2 1 1 3 3 3 0 Transcription factor zinc-finger Zn_Tnp_IS1 PF03811.8 ETS65207.1 - 8.2 6.0 7.3 1.9 8.0 0.8 2.7 2 1 0 2 2 2 0 InsA N-terminal domain zf-RING_3 PF14369.1 ETS65207.1 - 8.2 6.5 11.4 3.7 7.6 0.3 2.9 3 0 0 3 3 3 0 zinc-finger DUF3133 PF11331.3 ETS65207.1 - 8.6 6.0 8.7 11 5.6 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3133) zf-UBR PF02207.15 ETS65207.1 - 8.8 6.1 7.8 9.3 6.0 0.8 3.0 3 1 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) DUF2296 PF10058.4 ETS65207.1 - 9.6 6.0 12.9 8.6 6.1 0.2 3.4 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Aminotran_4 PF01063.14 ETS65208.1 - 1.2e-22 80.5 0.0 5.8e-22 78.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class IV Proteasome PF00227.21 ETS65209.1 - 7.9e-50 168.7 0.1 9.9e-50 168.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 ETS65209.1 - 1.1e-09 37.3 0.1 2.4e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF4520 PF15016.1 ETS65209.1 - 0.021 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF4116 PF13475.1 ETS65209.1 - 0.048 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Gp-FAR-1 PF05823.7 ETS65209.1 - 0.14 12.1 0.1 1.5 8.7 0.0 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PAC2 PF09754.4 ETS65210.1 - 3e-24 86.1 0.0 4.9e-24 85.4 0.0 1.5 1 1 0 1 1 1 1 PAC2 family EF-hand_4 PF12763.2 ETS65211.1 - 1.4e-37 127.5 0.0 4.1e-15 55.3 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 ETS65211.1 - 2.4e-07 30.7 0.0 0.0098 16.0 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.26 ETS65211.1 - 1.2e-05 24.9 0.0 4.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_1 PF00036.27 ETS65211.1 - 0.00032 19.7 0.0 1.2 8.5 0.0 4.8 5 0 0 5 5 5 1 EF hand Macoilin PF09726.4 ETS65211.1 - 0.00037 18.9 10.5 0.00067 18.0 7.3 1.3 1 0 0 1 1 1 1 Transmembrane protein zf-C4H2 PF10146.4 ETS65211.1 - 0.0011 18.9 2.2 0.0011 18.9 1.5 4.9 5 1 0 5 5 3 1 Zinc finger-containing protein CENP-Q PF13094.1 ETS65211.1 - 0.0051 16.8 29.8 0.014 15.4 7.6 2.5 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit UBA_3 PF09288.5 ETS65211.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain ERM PF00769.14 ETS65211.1 - 0.02 14.4 23.0 0.036 13.6 15.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMCO5 PF14992.1 ETS65211.1 - 0.13 11.3 19.1 0.19 10.8 13.2 1.2 1 0 0 1 1 1 0 TMCO5 family Myosin_tail_1 PF01576.14 ETS65211.1 - 0.16 9.6 31.1 0.016 12.9 9.7 2.0 1 1 1 2 2 2 0 Myosin tail AAA_13 PF13166.1 ETS65211.1 - 0.28 9.5 14.8 0.39 9.1 10.3 1.1 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 ETS65211.1 - 0.32 10.1 12.0 0.63 9.1 3.8 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CtIP_N PF10482.4 ETS65211.1 - 0.41 10.4 13.7 0.72 9.6 9.5 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Allexi_40kDa PF05549.6 ETS65211.1 - 0.55 9.4 6.1 1.1 8.5 4.2 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein ATG16 PF08614.6 ETS65211.1 - 0.95 9.2 25.4 2.2 8.0 7.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 ETS65211.1 - 1.6 8.1 21.3 3.9 6.8 14.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Snapin_Pallidin PF14712.1 ETS65211.1 - 3.3 8.0 17.7 2.2 8.6 8.0 2.4 1 1 1 2 2 2 0 Snapin/Pallidin APG6 PF04111.7 ETS65211.1 - 4 6.3 23.0 2.6 6.9 13.5 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Synaptobrevin PF00957.16 ETS65211.1 - 4.6 6.9 5.9 8.2 6.1 4.1 1.3 1 0 0 1 1 1 0 Synaptobrevin ADIP PF11559.3 ETS65211.1 - 4.7 7.0 26.2 1.1 9.1 12.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.1 ETS65211.1 - 6.8 6.0 27.7 0.53 9.6 15.6 1.7 2 1 0 2 2 1 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.6 ETS65211.1 - 8 4.6 21.7 17 3.5 15.1 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF399 PF04187.8 ETS65212.1 - 8.3e-23 80.9 0.6 1.7e-21 76.7 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF399 DPBB_1 PF03330.13 ETS65213.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.9 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PepSY_TM_3 PF13706.1 ETS65213.1 - 0.26 10.7 1.0 0.55 9.6 0.7 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix WW PF00397.21 ETS65214.1 - 1.4e-09 37.5 3.5 6.2e-05 22.7 2.4 2.5 2 0 0 2 2 2 2 WW domain gpUL132 PF11359.3 ETS65215.1 - 0.093 12.0 2.0 0.18 11.0 1.4 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 Pkinase PF00069.20 ETS65216.1 - 5.9e-71 238.6 0.0 8e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65216.1 - 3.5e-49 167.2 0.0 4.9e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS65216.1 - 1.6e-06 27.3 0.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.11 ETS65216.1 - 0.05 13.5 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC1 family Pkinase PF00069.20 ETS65217.1 - 1.3e-71 240.7 0.0 1.7e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65217.1 - 2.3e-32 112.0 0.0 2.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS65217.1 - 3.5e-08 32.7 0.0 1.2e-07 31.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 ETS65217.1 - 0.0017 17.4 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETS65217.1 - 0.0052 16.1 0.1 0.011 15.0 0.1 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 ETS65217.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family 5_nucleotid PF05761.9 ETS65217.1 - 0.04 12.4 0.2 0.04 12.4 0.1 1.4 2 0 0 2 2 2 0 5' nucleotidase family Mito_carr PF00153.22 ETS65218.1 - 1.7e-49 165.4 2.9 7.9e-17 60.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1129 PF06570.6 ETS65218.1 - 0.15 11.3 0.1 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DIE2_ALG10 PF04922.7 ETS65219.1 - 4.5e-72 243.1 14.8 1.3e-52 179.1 8.2 3.2 2 1 0 2 2 2 2 DIE2/ALG10 family Cu-oxidase_3 PF07732.10 ETS65219.1 - 7.8e-31 106.2 0.3 5.3e-28 97.1 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS65219.1 - 9e-21 74.4 0.0 1.2e-16 60.9 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS65219.1 - 3.8e-14 52.3 9.1 2.5e-13 49.7 3.4 3.5 3 1 0 3 3 3 1 Multicopper oxidase Mrr_cat PF04471.7 ETS65219.1 - 0.2 11.4 0.0 0.59 9.9 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease DUF389 PF04087.9 ETS65219.1 - 0.33 10.8 13.0 0.35 10.7 0.2 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF389) NAD_binding_5 PF07994.7 ETS65220.1 - 1.3e-109 366.2 0.0 1.7e-109 365.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 ETS65220.1 - 1.8e-43 146.8 0.0 3.2e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DHHA2 PF02833.9 ETS65220.1 - 0.041 14.0 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 DHHA2 domain LLC1 PF14945.1 ETS65220.1 - 0.093 13.0 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein HOOK PF05622.7 ETS65221.1 - 1.1e-54 185.5 70.4 6.4e-53 179.6 35.0 3.7 1 1 2 3 3 3 1 HOOK protein CH PF00307.26 ETS65221.1 - 0.0001 22.3 0.0 0.0027 17.7 0.0 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain Sec20 PF03908.8 ETS65221.1 - 0.14 11.8 17.4 0.099 12.3 1.0 4.6 4 0 0 4 4 4 0 Sec20 CENP-F_leu_zip PF10473.4 ETS65221.1 - 2.4 8.0 94.6 0.089 12.6 11.7 7.9 3 2 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TRAPP PF04051.11 ETS65222.1 - 1.3e-29 102.6 0.0 2.2e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF837 PF05769.6 ETS65222.1 - 0.00048 19.7 2.3 0.00048 19.7 1.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF837) DUF2188 PF09954.4 ETS65222.1 - 0.37 10.7 3.7 0.29 11.0 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Methyltransf_23 PF13489.1 ETS65223.1 - 3.2e-12 46.4 0.1 7.2e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS65223.1 - 7.7e-11 42.3 0.0 1.9e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS65223.1 - 2.5e-06 28.0 0.0 5.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS65223.1 - 6.1e-06 25.7 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS65223.1 - 6.4e-06 26.4 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS65223.1 - 1.9e-05 24.2 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS65223.1 - 7.1e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS65223.1 - 0.003 18.0 0.0 0.008 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 ETS65223.1 - 0.0059 15.6 0.0 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PTS_EIIA_2 PF00359.17 ETS65223.1 - 0.05 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Arf PF00025.16 ETS65224.1 - 1.8e-64 216.1 0.0 2.1e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 ETS65224.1 - 1.2e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 ETS65224.1 - 3.9e-12 45.8 0.0 4.4e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS65224.1 - 7.5e-12 45.7 0.0 9.6e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 ETS65224.1 - 3.8e-11 42.3 0.6 7.7e-09 34.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 ETS65224.1 - 5.4e-09 36.0 0.0 7.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETS65224.1 - 1.3e-07 31.0 0.0 1.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS65224.1 - 3.3e-07 29.9 0.0 9.3e-05 21.9 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 ETS65224.1 - 0.0016 17.7 0.2 0.0057 15.9 0.1 1.9 1 1 1 2 2 2 1 Ferrous iron transport protein B Mannosyl_trans2 PF04188.8 ETS65225.1 - 1.6e-49 169.0 11.7 2.2e-49 168.6 8.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF1757 PF08560.5 ETS65226.1 - 0.014 15.0 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) DUF883 PF05957.8 ETS65226.1 - 0.15 12.4 0.9 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Gly-zipper_Omp PF13488.1 ETS65226.1 - 6.1 6.5 17.9 1.7 8.3 0.4 2.6 2 1 0 2 2 2 0 Glycine zipper LSM14 PF12701.2 ETS65227.1 - 2.3e-31 107.4 0.0 3.7e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 ETS65227.1 - 2e-07 31.4 2.5 0.0032 17.9 0.4 2.9 2 1 0 2 2 2 2 FDF domain SM-ATX PF14438.1 ETS65227.1 - 0.00055 19.8 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Lon_C PF05362.8 ETS65228.1 - 1e-68 230.6 0.0 1.6e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 ETS65228.1 - 5.8e-23 81.5 0.0 1.4e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 ETS65228.1 - 4.7e-11 42.7 0.0 2.3e-10 40.5 0.0 2.0 1 1 1 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 ETS65228.1 - 1.1e-09 38.1 0.0 3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 ETS65228.1 - 1.3e-08 34.3 0.0 2.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 ETS65228.1 - 6.4e-05 22.9 0.0 0.00026 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 ETS65228.1 - 0.00024 21.9 2.6 0.00034 21.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS65228.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_19 PF13245.1 ETS65228.1 - 0.00025 20.7 0.1 0.00091 18.9 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS65228.1 - 0.00048 20.2 0.0 0.0075 16.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS65228.1 - 0.00059 19.7 0.0 0.0027 17.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 ETS65228.1 - 0.0044 16.6 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETS65228.1 - 0.0052 16.2 0.0 0.015 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS65228.1 - 0.0068 16.7 2.2 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETS65228.1 - 0.0072 15.4 0.1 0.021 13.9 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 ETS65228.1 - 0.0092 15.0 0.0 0.095 11.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 ETS65228.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 ETS65228.1 - 0.021 13.5 0.1 0.14 10.8 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus Zeta_toxin PF06414.7 ETS65228.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 ETS65228.1 - 0.023 14.8 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 ETS65228.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 ETS65228.1 - 0.027 14.0 0.1 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 ETS65228.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_PrkA PF08298.6 ETS65228.1 - 0.044 12.4 0.0 0.34 9.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.1 ETS65228.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS65228.1 - 0.064 12.3 0.0 22 4.0 0.0 3.1 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 ETS65228.1 - 0.079 12.6 0.0 0.25 10.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 ETS65228.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G-alpha PF00503.15 ETS65228.1 - 0.32 9.6 0.0 0.55 8.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Rad17 PF03215.10 ETS65228.1 - 0.36 9.4 0.0 0.56 8.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein eIF-5_eIF-2B PF01873.12 ETS65229.1 - 2.1e-39 134.0 0.0 3.2e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 ETS65229.1 - 1.4e-24 85.8 0.0 1.4e-24 85.8 0.0 2.8 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon MAPEG PF01124.13 ETS65230.1 - 1.1e-19 70.2 3.9 2.2e-19 69.3 2.7 1.5 1 0 0 1 1 1 1 MAPEG family MR_MLE PF01188.16 ETS65230.1 - 0.001 19.5 0.1 0.0026 18.2 0.1 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Ferritin_2 PF13668.1 ETS65231.1 - 3.7e-44 150.0 1.3 6.5e-44 149.2 0.9 1.4 1 0 0 1 1 1 1 Ferritin-like domain Cullin PF00888.17 ETS65232.1 - 1.8e-118 396.6 0.0 2.5e-118 396.2 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 ETS65232.1 - 6.9e-23 80.2 1.7 1.7e-22 79.0 1.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain PDEase_II PF02112.10 ETS65233.1 - 3e-39 134.9 0.0 3.6e-23 82.0 0.0 3.3 3 1 0 3 3 3 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 ETS65233.1 - 0.00028 20.5 0.0 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SPT16 PF08644.6 ETS65235.1 - 2e-55 186.8 0.0 4.4e-55 185.7 0.0 1.6 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 ETS65235.1 - 5.3e-49 165.8 0.2 1.5e-48 164.3 0.1 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 ETS65235.1 - 4.4e-26 91.7 0.1 1.3e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 Rtt106 PF08512.7 ETS65235.1 - 3.4e-21 75.0 0.1 1.1e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DNA_binding_1 PF01035.15 ETS65236.1 - 2e-23 81.9 0.0 2.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_6 PF12697.2 ETS65238.1 - 5.5e-33 114.7 0.3 6.9e-33 114.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS65238.1 - 6e-16 58.7 0.0 1e-14 54.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS65238.1 - 1.3e-14 54.1 0.0 3.4e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS65238.1 - 1.3e-06 27.8 0.4 0.013 14.7 0.2 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 ETS65238.1 - 1.8e-05 24.0 0.1 0.16 11.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 ETS65238.1 - 0.00074 19.8 0.1 0.0016 18.6 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 ETS65238.1 - 0.001 18.6 0.1 0.017 14.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 ETS65238.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 ETS65238.1 - 0.025 14.0 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 ETS65238.1 - 0.025 13.8 0.1 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.3 ETS65238.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.7 1 1 0 1 1 1 0 Putative lysophospholipase DUF2048 PF09752.4 ETS65238.1 - 0.047 12.5 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LEA_5 PF00477.12 ETS65238.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Small hydrophilic plant seed protein AAA PF00004.24 ETS65239.1 - 1.9e-33 115.4 0.0 3.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS65239.1 - 2.1e-09 37.6 0.2 2.3e-08 34.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS65239.1 - 3.7e-08 33.5 0.0 1.1e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS65239.1 - 1.3e-06 29.2 0.0 2.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS65239.1 - 4.2e-06 26.4 0.4 0.00015 21.4 0.0 3.2 3 1 0 3 3 3 1 Part of AAA domain AAA_33 PF13671.1 ETS65239.1 - 5e-06 26.4 0.6 3.3e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS65239.1 - 2.5e-05 24.5 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETS65239.1 - 4.9e-05 23.3 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 ETS65239.1 - 8.3e-05 22.3 0.5 0.0051 16.5 0.4 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 ETS65239.1 - 9.3e-05 21.9 3.1 0.013 14.9 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.1 ETS65239.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 ETS65239.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETS65239.1 - 0.00031 20.4 0.3 0.0026 17.4 0.2 2.4 1 1 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 ETS65239.1 - 0.00035 19.7 0.0 0.00069 18.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 ETS65239.1 - 0.00066 18.6 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 ETS65239.1 - 0.00093 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 ETS65239.1 - 0.00098 18.5 0.0 0.003 17.0 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 ETS65239.1 - 0.0013 18.4 0.4 0.0047 16.6 0.3 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 ETS65239.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 ETS65239.1 - 0.0017 18.5 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.9 ETS65239.1 - 0.0018 17.3 0.1 1.3 7.9 0.0 2.4 1 1 1 2 2 2 2 KAP family P-loop domain AAA_28 PF13521.1 ETS65239.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS65239.1 - 0.0026 16.8 0.0 0.0054 15.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 ETS65239.1 - 0.0027 17.3 0.0 0.0071 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS65239.1 - 0.0091 15.6 0.1 0.028 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETS65239.1 - 0.011 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 ETS65239.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 ETS65239.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_23 PF13476.1 ETS65239.1 - 0.037 14.3 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETS65239.1 - 0.04 13.0 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 ETS65239.1 - 0.049 12.7 0.4 1.1 8.3 0.0 2.5 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 ETS65239.1 - 0.056 12.6 0.1 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.9 ETS65239.1 - 0.072 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 ETS65239.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_3 PF07726.6 ETS65239.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.6 ETS65239.1 - 0.11 11.4 0.4 2.3 7.0 0.2 2.1 1 1 0 2 2 2 0 Rad51 Rad17 PF03215.10 ETS65239.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KTI12 PF08433.5 ETS65239.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 RskA PF10099.4 ETS65240.1 - 6.7 6.4 12.2 20 4.8 7.6 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Cyclin PF08613.6 ETS65241.1 - 3e-16 60.1 0.0 8.5e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 ETS65241.1 - 3.3e-07 29.9 0.0 5.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 ETS65242.1 - 2.9e-08 33.2 4.6 1.3e-05 24.8 0.9 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 ETS65242.1 - 3.8e-06 26.4 0.2 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.7 ETS65242.1 - 0.00096 18.7 0.6 0.74 9.5 0.2 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETS65242.1 - 0.024 13.2 0.1 0.75 8.3 0.0 2.6 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 ETS65242.1 - 0.025 13.6 0.1 0.058 12.4 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 ETS65242.1 - 0.059 13.0 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 ETS65242.1 - 2.7 7.4 7.6 13 5.2 0.7 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature zf-HC5HC2H_2 PF13832.1 ETS65243.1 - 1.1e-20 73.6 20.6 9.7e-20 70.6 0.8 4.0 3 0 0 3 3 3 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETS65243.1 - 2.9e-15 56.1 2.3 2.9e-15 56.1 1.6 4.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.24 ETS65243.1 - 1.5e-14 53.3 58.0 3.8e-10 39.3 4.5 5.8 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 ETS65243.1 - 1.6e-08 33.6 4.3 1.6e-08 33.6 3.0 4.7 7 0 0 7 7 7 2 PHD-finger BAH PF01426.13 ETS65243.1 - 3.2e-08 33.3 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 BAH domain GATA PF00320.22 ETS65243.1 - 1.4e-06 27.5 2.9 1.4e-06 27.5 2.0 3.4 3 0 0 3 3 3 1 GATA zinc finger ELM2 PF01448.19 ETS65243.1 - 0.058 14.0 0.0 0.35 11.5 0.0 2.3 2 0 0 2 2 2 0 ELM2 domain bZIP_1 PF00170.16 ETS65244.1 - 8.6e-06 25.6 6.7 2.1e-05 24.4 4.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor EndoU_bacteria PF14436.1 ETS65244.1 - 0.082 12.7 0.2 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial EndoU nuclease bZIP_2 PF07716.10 ETS65244.1 - 0.11 12.3 5.9 1.8 8.4 4.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper SPRY PF00622.23 ETS65245.1 - 2.1e-20 73.0 0.1 3.3e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Arf PF00025.16 ETS65246.1 - 2.6e-77 257.9 0.0 3.1e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETS65246.1 - 1e-12 47.7 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 ETS65246.1 - 9.5e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 ETS65246.1 - 1e-10 40.8 1.2 6.8e-07 28.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 ETS65246.1 - 1e-09 37.8 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS65246.1 - 2.3e-07 31.2 0.0 3.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS65246.1 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 ETS65246.1 - 0.0012 17.9 0.1 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 ETS65246.1 - 0.044 13.2 0.0 0.25 10.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Cys_Met_Meta_PP PF01053.15 ETS65247.1 - 2.7e-148 493.4 0.0 3e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETS65247.1 - 8e-12 44.8 0.3 1.2e-11 44.2 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 ETS65247.1 - 1.8e-10 40.1 0.4 3.1e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 ETS65247.1 - 4.1e-08 32.5 0.1 6.3e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS65247.1 - 2.6e-05 23.4 0.0 3.7e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 ETS65247.1 - 0.00097 17.5 0.1 0.0015 16.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 ETS65247.1 - 0.0057 15.3 0.0 0.0081 14.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 ETS65247.1 - 0.17 10.3 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) F_actin_cap_B PF01115.12 ETS65248.1 - 4e-99 330.7 0.0 5.7e-99 330.2 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit UDPGP PF01704.13 ETS65249.1 - 1.5e-182 606.8 0.3 1.7e-182 606.6 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase RRM_5 PF13893.1 ETS65250.1 - 3.6e-14 52.3 0.0 2.4e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS65250.1 - 7.3e-13 47.9 0.0 1e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS65250.1 - 2.5e-07 30.5 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) COX14 PF14880.1 ETS65250.1 - 0.019 14.6 0.2 0.051 13.2 0.2 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF3429 PF11911.3 ETS65251.1 - 1.7e-39 135.0 13.3 2.4e-39 134.5 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Med2 PF11214.3 ETS65251.1 - 0.37 10.8 10.9 0.75 9.8 7.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 RNA_polI_A34 PF08208.6 ETS65251.1 - 1.5 8.4 19.7 2.4 7.7 13.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF202 PF02656.10 ETS65252.1 - 2.8e-10 40.2 5.6 7.6e-10 38.8 3.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Response_reg PF00072.19 ETS65253.1 - 2.7e-22 78.9 0.5 3.5e-15 55.9 0.2 2.3 1 1 1 2 2 2 2 Response regulator receiver domain AMOP PF03782.12 ETS65253.1 - 0.14 12.1 1.7 0.24 11.3 1.2 1.3 1 0 0 1 1 1 0 AMOP domain AAA_5 PF07728.9 ETS65255.1 - 1.3e-61 206.3 0.0 8.8e-27 93.5 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) Mito_carr PF00153.22 ETS65258.1 - 1.1e-64 214.2 2.0 1.6e-21 75.8 0.2 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Sep15_SelM PF08806.6 ETS65259.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain Dioxygenase_C PF00775.16 ETS65260.1 - 1.6e-46 157.8 0.0 2.1e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 ETS65260.1 - 4.9e-14 52.0 0.0 8.8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 ETS65260.1 - 9.1e-07 28.8 0.0 3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain PPR_2 PF13041.1 ETS65261.1 - 6e-13 48.5 0.0 1.8e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 ETS65261.1 - 1.6e-08 34.1 0.6 8.5e-06 25.6 0.0 4.8 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 ETS65261.1 - 6.4e-08 32.0 0.0 3e-05 23.7 0.0 3.7 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 ETS65261.1 - 3.8e-06 26.2 0.2 0.0086 15.5 0.1 2.6 2 0 0 2 2 2 2 PPR repeat CHCH PF06747.8 ETS65262.1 - 1.1e-05 25.1 6.1 1.1e-05 25.1 4.2 2.3 2 0 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 ETS65262.1 - 0.29 11.2 10.7 1.2 9.1 6.1 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 ETS65262.1 - 0.64 10.0 4.1 0.93 9.5 1.9 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) zf-C3HC4_2 PF13923.1 ETS65262.1 - 0.9 9.6 3.2 2.9 7.9 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cmc1 PF08583.5 ETS65262.1 - 2.1 8.2 12.6 1.5 8.6 2.5 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Iso_dh PF00180.15 ETS65263.1 - 3.2e-98 328.8 0.0 3.7e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aldedh PF00171.17 ETS65264.1 - 3.1e-144 480.7 0.0 3.7e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 ETS65264.1 - 9.6e-05 21.7 0.1 0.00027 20.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Zn_clus PF00172.13 ETS65265.1 - 0.00065 19.5 9.1 0.0012 18.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 ETS65265.1 - 0.087 13.0 6.1 0.2 11.8 4.2 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region 3-HAO PF06052.7 ETS65266.1 - 1.8e-57 192.9 0.0 2.3e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 ETS65266.1 - 1.3e-05 24.5 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS65266.1 - 0.0012 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 ETS65266.1 - 0.0065 16.4 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Ricin_B_lectin PF00652.17 ETS65268.1 - 0.069 13.1 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Gag_spuma PF03276.9 ETS65268.1 - 0.16 10.2 0.3 0.22 9.8 0.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein SGL PF08450.7 ETS65269.1 - 1.6e-15 57.1 0.2 3.1e-14 52.9 0.1 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region CDC45 PF02724.9 ETS65270.1 - 0.54 8.2 2.4 0.57 8.1 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETS65270.1 - 1.2 8.3 7.5 1.7 7.8 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETS65270.1 - 3 5.6 11.2 3.3 5.4 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 ETS65270.1 - 7.1 5.5 6.7 8.3 5.3 4.6 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 ETS65270.1 - 7.7 5.6 9.2 8.7 5.5 6.4 1.1 1 0 0 1 1 1 0 SDA1 Mmp37 PF09139.6 ETS65272.1 - 4.4e-107 357.9 0.0 5.2e-107 357.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Aldedh PF00171.17 ETS65274.1 - 5.1e-158 526.2 2.9 6.3e-158 525.9 2.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 ETS65274.1 - 0.01 15.0 0.0 0.043 13.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) WD40 PF00400.27 ETS65275.1 - 1.3e-08 34.3 3.2 0.009 15.8 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-U1 PF06220.7 ETS65276.1 - 2.5e-19 68.5 4.2 3.5e-19 68.0 2.9 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 ETS65276.1 - 0.02 15.0 2.1 0.035 14.2 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SPOB_a PF14689.1 ETS65276.1 - 0.15 11.6 0.3 0.21 11.1 0.2 1.1 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain Amino_oxidase PF01593.19 ETS65277.1 - 4.6e-23 82.0 1.0 5.8e-15 55.3 0.0 2.7 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase Snf7 PF03357.16 ETS65277.1 - 6.9e-21 74.3 8.5 6.9e-21 74.3 5.9 3.5 2 1 2 4 4 4 1 Snf7 NAD_binding_8 PF13450.1 ETS65277.1 - 9.8e-15 54.3 0.0 4.2e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS65277.1 - 0.00015 20.7 0.1 0.00036 19.4 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 ETS65277.1 - 0.00022 21.0 0.1 0.13 12.0 0.0 3.0 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS65277.1 - 0.00027 19.9 0.0 0.002 17.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 ETS65277.1 - 0.0085 14.6 0.0 0.083 11.3 0.0 2.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 ETS65277.1 - 0.0095 16.3 0.2 0.057 13.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS65277.1 - 0.044 13.8 0.1 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HALZ PF02183.13 ETS65277.1 - 0.56 9.9 13.8 0.027 14.1 0.5 3.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper Beta-lactamase PF00144.19 ETS65278.1 - 1.5e-33 116.1 0.0 3.2e-33 115.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Aldo_ket_red PF00248.16 ETS65280.1 - 1.1e-55 188.4 0.0 1.5e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family bZIP_1 PF00170.16 ETS65281.1 - 0.0017 18.2 19.7 0.0017 18.2 13.7 2.4 2 1 0 2 2 2 1 bZIP transcription factor DUF2036 PF09724.4 ETS65283.1 - 3.3e-53 180.9 0.0 3.9e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF2893 PF11459.3 ETS65283.1 - 0.021 14.5 1.5 0.029 14.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) tRNA_m1G_MT PF01746.16 ETS65284.1 - 1.6e-24 86.5 0.0 1.5e-19 70.2 0.0 2.5 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Pol_alpha_B_N PF08418.5 ETS65285.1 - 0.2 11.1 5.7 0.29 10.6 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF755 PF05501.6 ETS65285.1 - 2.9 7.9 13.4 0.061 13.3 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Herpes_capsid PF06112.6 ETS65285.1 - 4.9 7.1 12.2 9.5 6.2 8.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Chon_Sulph_att PF06566.6 ETS65287.1 - 0.0029 17.2 2.3 0.0035 17.0 1.6 1.2 1 0 0 1 1 1 1 Chondroitin sulphate attachment domain zf-H2C2_2 PF13465.1 ETS65289.1 - 7.1e-07 29.2 25.1 1.1e-05 25.4 3.6 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETS65289.1 - 1.2e-06 28.5 19.0 0.0013 18.9 1.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS65289.1 - 0.00091 19.3 17.4 0.013 15.8 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger eIF3_subunit PF08597.5 ETS65290.1 - 6.1e-52 176.6 30.4 7.2e-52 176.3 21.0 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit S1FA PF04689.8 ETS65290.1 - 0.28 11.0 4.5 1.5 8.7 0.7 2.9 3 0 0 3 3 3 0 DNA binding protein S1FA SR-25 PF10500.4 ETS65290.1 - 0.91 8.9 18.2 0.15 11.4 5.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein rRNA_processing PF08524.6 ETS65290.1 - 2.9 7.6 17.3 0.17 11.6 7.0 2.1 2 0 0 2 2 2 0 rRNA processing Response_reg PF00072.19 ETS65291.1 - 5.8e-19 68.1 0.1 1.8e-18 66.6 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 ETS65291.1 - 4.7e-15 55.2 0.0 1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS65291.1 - 1e-05 25.4 1.0 3.8e-05 23.6 0.7 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain F-box-like PF12937.2 ETS65292.1 - 1.6e-05 24.4 0.2 0.046 13.4 0.0 2.8 2 0 0 2 2 2 2 F-box-like TPR_11 PF13414.1 ETS65292.1 - 0.00057 19.4 0.8 0.0017 17.9 0.6 1.8 1 0 0 1 1 1 1 TPR repeat MIT PF04212.13 ETS65292.1 - 0.0022 17.8 0.2 0.0062 16.3 0.1 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain F-box PF00646.28 ETS65292.1 - 0.0028 17.2 2.2 0.29 10.8 0.2 2.4 2 0 0 2 2 2 2 F-box domain TPR_2 PF07719.12 ETS65292.1 - 0.0029 17.3 0.3 0.0098 15.7 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS65292.1 - 0.014 14.9 0.2 0.078 12.6 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS65292.1 - 0.034 14.7 1.1 0.15 12.7 0.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Tubulin_3 PF14881.1 ETS65293.1 - 1e-31 109.8 0.3 4.2e-31 107.8 0.2 1.9 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 ETS65293.1 - 5e-27 94.2 0.2 1.3e-26 92.9 0.1 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 ETS65293.1 - 0.00054 19.8 0.0 0.97 9.2 0.0 3.0 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain UBX PF00789.15 ETS65294.1 - 3.1e-06 27.1 0.0 9.4e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 UBX domain zf-C2H2 PF00096.21 ETS65294.1 - 0.024 14.9 0.3 0.045 14.1 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 ETS65294.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF572 PF04502.8 ETS65294.1 - 4.3 6.4 21.5 4 6.5 13.5 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF572) CoaE PF01121.15 ETS65295.1 - 4.2e-51 172.8 0.0 5.6e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 ETS65295.1 - 3.2e-05 24.7 0.5 0.00054 20.7 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS65295.1 - 0.079 13.2 0.1 2.4 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 ETS65296.1 - 1.2e-32 112.9 41.1 1.2e-32 112.9 28.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 ETS65297.1 - 0.0034 17.2 1.7 0.0034 17.2 1.2 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 ETS65298.1 - 2.2e-73 246.6 0.0 2.7e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65298.1 - 3e-31 108.4 0.0 4.1e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS65298.1 - 0.00012 21.1 0.0 0.016 14.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETS65298.1 - 0.044 13.5 1.3 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS65299.1 - 2.5e-35 122.0 0.0 3.6e-23 82.2 0.0 2.7 3 0 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.18 ETS65299.1 - 7.9e-06 25.7 0.3 0.0085 15.8 0.0 2.9 2 0 0 2 2 2 2 Phosphotransferase enzyme family Hira PF07569.6 ETS65301.1 - 6.3e-54 182.4 0.0 1.4e-53 181.3 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 ETS65301.1 - 2.1e-41 138.3 23.1 1.1e-09 37.8 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 ETS65301.1 - 4.4e-10 38.8 0.6 1.2e-09 37.4 0.4 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 ETS65301.1 - 0.048 13.3 1.0 2 8.1 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Semialdhyde_dhC PF02774.13 ETS65302.1 - 6.3e-45 153.2 0.0 1e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 ETS65302.1 - 7.5e-28 97.2 0.0 1.5e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 ETS65302.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 ETS65302.1 - 0.018 15.5 0.0 0.048 14.2 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Gp_dh_C PF02800.15 ETS65302.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CTP_transf_1 PF01148.15 ETS65303.1 - 9.6e-17 61.4 1.6 1.8e-12 47.5 0.6 3.0 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_L35p PF01632.14 ETS65303.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L35 Glyco_hydro_43 PF04616.9 ETS65304.1 - 1.7e-35 122.5 0.0 2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ACOX PF01756.14 ETS65305.1 - 1.1e-46 158.6 0.0 2.2e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 ETS65305.1 - 1.3e-13 50.1 0.5 4e-13 48.6 0.4 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 ETS65305.1 - 4.2e-10 39.9 0.0 1.6e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 ETS65305.1 - 9.4e-08 32.2 2.4 1.4e-06 28.5 1.5 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain COPIIcoated_ERV PF07970.7 ETS65306.1 - 3.1e-69 232.9 0.2 5.3e-69 232.2 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 ETS65306.1 - 1.6e-33 114.5 0.2 6e-33 112.7 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Uds1 PF15456.1 ETS65307.1 - 9.1e-19 67.6 3.2 9.1e-19 67.6 2.2 9.6 5 2 4 9 9 9 2 Up-regulated During Septation Filament PF00038.16 ETS65307.1 - 0.0026 17.2 9.6 0.0026 17.2 6.7 6.8 3 1 2 5 5 5 2 Intermediate filament protein Complex1_49kDa PF00346.14 ETS65308.1 - 3.2e-127 423.1 0.0 4.3e-127 422.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 ETS65308.1 - 0.037 12.7 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Pkinase PF00069.20 ETS65309.1 - 4.4e-70 235.8 0.0 5.9e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65309.1 - 2.2e-35 122.0 0.0 3.5e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS65309.1 - 3.5e-05 22.9 0.1 0.0001 21.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETS65309.1 - 0.016 14.2 0.4 0.047 12.7 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.18 ETS65310.1 - 3.7e-106 354.9 0.1 4.4e-106 354.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS65310.1 - 6.4e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS65310.1 - 3.4e-05 24.2 0.1 0.029 14.8 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 ETS65310.1 - 0.00051 19.6 0.0 0.0048 16.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal G6PD_C PF02781.11 ETS65312.1 - 2e-124 414.2 0.0 2.8e-124 413.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 ETS65312.1 - 1e-61 208.3 0.0 1.7e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Rad4 PF03835.10 ETS65313.1 - 3.5e-28 97.8 0.2 1e-27 96.3 0.2 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 ETS65313.1 - 1.7e-25 88.5 0.1 3.6e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 ETS65313.1 - 4.7e-13 48.4 0.0 1.1e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 ETS65313.1 - 1.8e-12 47.4 0.2 1.8e-12 47.4 0.1 2.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 ETS65313.1 - 5.3e-08 33.0 1.3 7.7e-06 26.0 0.0 3.3 3 0 0 3 3 3 1 Transglutaminase-like superfamily PI3_PI4_kinase PF00454.22 ETS65314.1 - 2.9e-31 108.7 0.0 4.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 ETS65314.1 - 3.2e-05 23.1 0.4 6e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.3 ETS65314.1 - 0.0035 17.0 0.1 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 OCD_Mu_crystall PF02423.10 ETS65315.1 - 2.4e-23 82.3 5.4 7.4e-23 80.7 3.8 1.8 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family WD40 PF00400.27 ETS65317.1 - 5e-06 26.1 3.0 0.0053 16.6 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Autophagy_act_C PF03987.10 ETS65318.1 - 4.7e-06 26.6 0.0 1.4e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_85 PF03644.8 ETS65318.1 - 0.01 14.9 0.1 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 WD40 PF00400.27 ETS65320.1 - 1.9e-33 113.1 12.6 1.2e-07 31.3 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nha1_C PF08619.5 ETS65320.1 - 0.017 14.3 4.1 0.031 13.5 2.8 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Nucleoporin_N PF08801.6 ETS65320.1 - 0.066 11.9 0.0 1.8 7.2 0.0 2.6 3 0 0 3 3 3 0 Nup133 N terminal like CLTH PF10607.4 ETS65321.1 - 2.7e-19 69.2 0.0 4.9e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 ETS65321.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 LisH NADH-G_4Fe-4S_3 PF10588.4 ETS65321.1 - 7.1 5.9 6.0 3.3 7.0 0.2 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NIF PF03031.13 ETS65322.1 - 6.5e-12 45.4 0.0 4.8e-05 23.0 0.0 3.3 2 1 0 2 2 2 2 NLI interacting factor-like phosphatase PP_kinase_C PF13090.1 ETS65323.1 - 0.091 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain zf-RING_2 PF13639.1 ETS65324.1 - 1e-06 28.4 8.3 1e-06 28.4 5.8 1.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETS65324.1 - 7.9e-06 25.4 4.4 7.9e-06 25.4 3.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS65324.1 - 1.4e-05 24.7 4.6 1.4e-05 24.7 3.2 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS65324.1 - 0.00079 19.4 11.6 0.0052 16.7 8.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS65324.1 - 0.0027 17.3 4.5 0.0072 16.0 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Parvo_coat PF00740.13 ETS65324.1 - 5.2 5.9 6.7 7.4 5.4 4.6 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 zf-rbx1 PF12678.2 ETS65324.1 - 5.4 7.2 14.0 0.079 13.0 2.6 2.7 3 0 0 3 3 3 0 RING-H2 zinc finger Arginase PF00491.16 ETS65325.1 - 1.1e-79 267.6 0.0 1.3e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family Methyltransf_18 PF12847.2 ETS65326.1 - 2.1e-06 28.3 0.0 3.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS65326.1 - 4.6e-06 26.3 0.0 6.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS65326.1 - 7.7e-05 23.1 0.0 0.00035 20.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS65326.1 - 0.00021 21.7 0.0 0.00048 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS65326.1 - 0.00031 20.4 0.0 0.0018 18.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 ETS65326.1 - 0.0088 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ribosomal_S26e PF01283.14 ETS65328.1 - 3.1e-46 156.3 4.8 5.1e-46 155.6 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S26e WW PF00397.21 ETS65329.1 - 6.9e-11 41.8 0.4 1.4e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 WW domain Alg14 PF08660.6 ETS65330.1 - 1e-49 168.7 0.0 1.3e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glutaredoxin PF00462.19 ETS65331.1 - 5.3e-14 51.9 0.0 7.6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 ETS65331.1 - 0.00052 20.2 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 ETS65331.1 - 0.0019 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 ETS65331.1 - 0.0087 16.2 0.1 0.02 15.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 ETS65331.1 - 0.024 14.2 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 ETS65331.1 - 0.033 13.7 0.1 0.069 12.6 0.1 1.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF953 PF06110.6 ETS65331.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 ETS65331.1 - 0.067 12.7 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin EpuA PF11772.3 ETS65332.1 - 0.074 12.4 0.1 0.24 10.8 0.1 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Pkinase PF00069.20 ETS65333.1 - 4.3e-68 229.2 0.0 5.5e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65333.1 - 5e-27 94.6 0.0 6.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Slu7 PF11708.3 ETS65334.1 - 2e-80 270.0 17.2 2e-80 270.0 11.9 2.2 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 ETS65334.1 - 0.14 11.8 1.0 0.27 10.9 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Sigma70_ner PF04546.8 ETS65334.1 - 0.77 9.3 15.3 2.5 7.6 4.4 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region RRM_6 PF14259.1 ETS65336.1 - 0.00052 19.9 0.0 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BTB_2 PF02214.17 ETS65337.1 - 2.4e-05 24.4 0.0 0.33 11.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Pkinase PF00069.20 ETS65338.1 - 4.5e-61 206.2 3.7 1.6e-41 142.2 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65338.1 - 4.5e-24 84.9 7.9 6e-20 71.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS65338.1 - 0.00012 21.2 2.3 0.00047 19.2 0.0 2.9 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.19 ETS65338.1 - 0.033 14.7 0.1 0.11 12.9 0.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 ETS65338.1 - 0.041 13.6 0.0 0.041 13.6 0.0 3.9 1 1 3 4 4 4 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETS65338.1 - 0.056 12.2 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 ETS65338.1 - 0.15 10.8 0.1 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GMC_oxred_N PF00732.14 ETS65339.1 - 8.9e-71 238.4 0.2 1.6e-70 237.6 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS65339.1 - 1.1e-33 116.5 0.0 2.5e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 ETS65339.1 - 3.1e-06 27.3 0.1 0.017 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS65339.1 - 1.9e-05 24.5 0.1 7.2e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS65339.1 - 2.3e-05 23.4 0.1 4.9e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 ETS65339.1 - 4.3e-05 22.5 2.5 0.00034 19.6 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS65339.1 - 0.00016 20.7 2.3 0.00051 19.0 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain Collagen PF01391.13 ETS65339.1 - 0.0011 18.4 12.4 0.0023 17.4 8.6 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pyr_redox_2 PF07992.9 ETS65339.1 - 0.003 17.4 0.8 0.007 16.2 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS65339.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 ETS65339.1 - 0.024 13.7 0.3 0.05 12.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family ChAPs PF09295.5 ETS65340.1 - 1.9e-157 524.0 0.0 3.1e-157 523.3 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 ETS65340.1 - 1.7e-06 28.2 4.7 6.2e-05 23.2 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS65340.1 - 3.1e-05 23.5 5.8 0.0051 16.4 0.1 4.3 3 1 0 3 3 3 1 TPR repeat Apc3 PF12895.2 ETS65340.1 - 0.00044 20.3 3.5 0.36 10.9 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETS65340.1 - 0.0014 18.9 2.5 8.4 7.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS65340.1 - 0.0078 16.0 6.4 2 8.5 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS65340.1 - 0.025 15.1 13.9 5.2 7.9 0.1 6.7 4 2 4 8 8 8 0 Tetratricopeptide repeat Ribosom_S12_S23 PF00164.20 ETS65341.1 - 2.2e-46 156.2 1.2 2.6e-46 156.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PH_4 PF15404.1 ETS65342.1 - 1.2e-44 152.1 0.9 5.4e-44 149.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain DUF4484 PF14831.1 ETS65342.1 - 0.00049 20.2 1.0 0.00049 20.2 0.7 2.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4484) Rhodanese PF00581.15 ETS65342.1 - 0.047 14.0 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Rhodanese-like domain IPK PF03770.11 ETS65343.1 - 2.1e-38 131.9 0.0 4.9e-37 127.4 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase TPR_11 PF13414.1 ETS65344.1 - 6.7e-08 32.0 3.5 0.005 16.4 0.1 3.1 2 1 1 3 3 3 3 TPR repeat Histone_HNS PF00816.16 ETS65344.1 - 0.0045 17.4 2.5 0.9 10.0 0.4 2.8 3 0 0 3 3 3 2 H-NS histone family TPR_2 PF07719.12 ETS65344.1 - 0.0098 15.7 2.0 5.5 7.1 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS65344.1 - 0.05 13.2 0.1 5 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HGTP_anticodon2 PF12745.2 ETS65344.1 - 0.1 11.7 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs TPR_16 PF13432.1 ETS65344.1 - 0.23 12.1 11.1 0.4 11.4 0.8 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS65344.1 - 2.5 8.9 8.9 0.91 10.3 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank PF00023.25 ETS65345.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat SRP14 PF02290.10 ETS65346.1 - 2.9e-23 81.5 0.1 2.9e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Rota_VP2 PF05087.7 ETS65346.1 - 3.6 5.3 5.1 4.5 5.0 3.5 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF726 PF05277.7 ETS65347.1 - 2.8e-114 381.6 1.1 3.9e-114 381.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 ETS65347.1 - 0.0035 17.0 1.2 0.0086 15.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Transketolase_N PF00456.16 ETS65349.1 - 1.9e-147 490.4 0.0 2.6e-147 489.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 ETS65349.1 - 1.6e-41 141.7 0.0 3e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ETS65349.1 - 3.9e-12 46.1 0.0 9.2e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 ETS65349.1 - 0.0028 16.6 0.2 0.14 11.0 0.1 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase LigB PF02900.13 ETS65351.1 - 8.3e-25 87.2 0.2 5.9e-24 84.4 0.1 2.1 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.11 ETS65352.1 - 1.3e-43 149.1 24.8 1.3e-43 149.1 17.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS65352.1 - 1.8e-14 53.2 15.7 1.2e-13 50.4 11.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 ETS65352.1 - 0.0015 16.7 5.1 0.015 13.4 0.1 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_2 PF00890.19 ETS65353.1 - 7.2e-89 298.5 0.1 7.2e-89 298.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 ETS65353.1 - 6e-21 74.0 0.1 1.8e-20 72.4 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 ETS65353.1 - 2.7e-14 52.8 0.9 2.2e-13 49.8 0.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS65353.1 - 6.9e-11 42.0 0.2 6.6e-10 38.8 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS65353.1 - 7.8e-11 42.2 0.0 7.7e-09 35.7 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS65353.1 - 2.9e-09 36.4 0.2 6e-09 35.4 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS65353.1 - 6.7e-07 28.1 3.1 0.00011 20.8 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 ETS65353.1 - 7.5e-07 28.3 1.0 0.0047 15.8 0.3 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 ETS65353.1 - 3.6e-06 26.2 0.4 0.00094 18.3 0.2 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 ETS65353.1 - 9.8e-06 24.8 2.1 3.8e-05 22.8 1.4 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS65353.1 - 2.7e-05 24.3 1.1 8.7e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS65353.1 - 9e-05 22.8 0.9 0.0016 18.8 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS65353.1 - 0.00015 20.9 0.0 0.003 16.7 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 ETS65353.1 - 0.0049 16.4 0.1 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 ETS65353.1 - 0.0083 15.9 0.3 0.09 12.5 0.2 2.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 ETS65353.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 ETS65353.1 - 0.02 13.8 0.2 0.04 12.8 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 ETS65353.1 - 0.037 12.3 0.0 0.06 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Nfu_N PF08712.6 ETS65354.1 - 3.2e-32 110.0 0.0 7e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 ETS65354.1 - 1.3e-21 76.1 0.1 2.2e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain ECH PF00378.15 ETS65355.1 - 1.2e-79 266.9 2.0 1.5e-79 266.5 1.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETS65355.1 - 6e-05 22.8 0.3 0.031 14.0 0.0 2.7 2 2 0 2 2 2 2 Peptidase family S49 ECH_C PF13766.1 ETS65355.1 - 0.036 14.2 0.4 0.18 11.9 0.1 2.0 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Spc97_Spc98 PF04130.8 ETS65357.1 - 1.2e-64 218.5 0.0 2e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DNA_pol_E_B PF04042.11 ETS65358.1 - 7.4e-41 139.7 0.0 1.6e-40 138.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DUF572 PF04502.8 ETS65360.1 - 1e-80 271.4 9.5 3e-80 269.8 6.6 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) Sporozoite_P67 PF05642.6 ETS65360.1 - 0.034 12.0 0.4 0.044 11.6 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TOM20_plant PF06552.7 ETS65360.1 - 0.05 13.1 0.2 3.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Benyvirus_14KDa PF07255.6 ETS65360.1 - 0.06 13.2 0.3 0.56 10.0 0.0 2.0 1 1 1 2 2 2 0 Benyvirus 14KDa protein Parathyroid PF01279.12 ETS65360.1 - 1.7 9.3 4.7 4.3 8.0 0.1 2.8 2 1 1 3 3 3 0 Parathyroid hormone family MARVEL PF01284.18 ETS65361.1 - 0.016 14.9 13.0 0.029 14.1 7.6 2.2 1 1 1 2 2 2 0 Membrane-associating domain DUF2583 PF10762.4 ETS65361.1 - 0.088 12.9 0.3 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) CRAL_TRIO PF00650.15 ETS65363.1 - 5.8e-41 139.6 0.0 9.2e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Hydrolase_6 PF13344.1 ETS65363.1 - 4.6e-29 100.2 0.0 9.7e-29 99.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS65363.1 - 6.6e-18 64.1 0.1 4.5e-17 61.5 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 ETS65363.1 - 2.2e-15 57.6 0.0 5.7e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CRAL_TRIO_2 PF13716.1 ETS65363.1 - 2.7e-13 50.0 0.0 4.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HAD_2 PF13419.1 ETS65363.1 - 1.1e-05 25.7 1.9 0.047 13.9 0.1 3.3 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase CRAL_TRIO_N PF03765.10 ETS65363.1 - 1.7e-05 24.8 0.1 5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PGP_phosphatase PF09419.5 ETS65363.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DFF40 PF09230.5 ETS65364.1 - 0.093 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa CMD PF02627.15 ETS65365.1 - 2e-09 37.1 0.4 7.8e-09 35.2 0.1 2.1 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family DUF1294 PF06961.8 ETS65365.1 - 0.096 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Mito_carr PF00153.22 ETS65366.1 - 1.2e-52 175.5 5.1 2.2e-18 65.7 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein PGM_PMM_I PF02878.11 ETS65367.1 - 5.8e-20 71.1 0.1 2.9e-10 39.7 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 ETS65367.1 - 1.1e-11 44.9 0.0 7e-11 42.3 0.0 2.4 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 ETS65367.1 - 3.1e-08 33.5 0.0 7.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 ETS65367.1 - 0.014 15.4 0.1 0.045 13.7 0.0 1.9 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ORMDL PF04061.9 ETS65368.1 - 1.3e-56 189.9 2.4 1.6e-56 189.6 1.7 1.1 1 0 0 1 1 1 1 ORMDL family DUF663 PF04950.7 ETS65369.1 - 1.6e-88 296.4 0.0 2.7e-88 295.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 ETS65369.1 - 1.5e-21 75.6 0.0 3.3e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain eIF_4EBP PF05456.6 ETS65370.1 - 7.6e-12 44.9 0.3 8.6e-12 44.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Mito_carr PF00153.22 ETS65371.1 - 2.2e-66 219.6 0.3 7.9e-26 89.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad52_Rad22 PF04098.10 ETS65372.1 - 1.4e-59 200.2 0.1 1.3e-58 197.1 0.0 2.0 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 ETS65372.1 - 5 5.2 14.3 7 4.7 9.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1687 PF07955.6 ETS65373.1 - 7.7e-07 29.1 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1687) F-box PF00646.28 ETS65374.1 - 3.2e-08 33.0 0.7 7.5e-08 31.8 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS65374.1 - 6.4e-05 22.6 5.7 0.00017 21.2 3.9 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 ETS65374.1 - 0.0046 16.7 0.0 0.46 10.4 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DDOST_48kD PF03345.9 ETS65375.1 - 1.2e-100 336.9 0.0 2.3e-62 210.9 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta Gly_radical PF01228.16 ETS65375.1 - 0.013 15.8 0.0 0.036 14.4 0.0 1.8 1 0 0 1 1 1 0 Glycine radical VIT1 PF01988.14 ETS65375.1 - 3.1 7.2 8.7 0.15 11.5 1.1 2.1 2 0 0 2 2 2 0 VIT family SynMuv_product PF06047.6 ETS65376.1 - 1.3e-50 169.5 1.6 3.2e-50 168.2 1.1 1.7 1 0 0 1 1 1 1 Ras-induced vulval development antagonist ATP_bind_4 PF01902.12 ETS65377.1 - 1.6e-39 135.5 0.0 1.4e-27 96.5 0.0 2.5 3 0 0 3 3 3 2 ATP-binding region Ribonuc_L-PSP PF01042.16 ETS65377.1 - 3.3e-13 49.4 0.0 1.8e-07 30.9 0.0 2.9 3 0 0 3 3 3 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 ETS65377.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase SUV3_C PF12513.3 ETS65378.1 - 7.2e-15 54.1 0.2 1.4e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 ETS65378.1 - 3.8e-12 45.8 0.1 1.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.1 ETS65378.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase_C-like LrgB PF04172.11 ETS65379.1 - 1.9e-19 69.6 9.3 1.9e-19 69.6 6.4 2.6 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.9 ETS65379.1 - 0.00027 20.5 3.8 0.00027 20.5 2.7 3.1 3 1 0 3 3 3 1 LrgA family Myc_N PF01056.13 ETS65379.1 - 0.067 12.3 4.1 0.1 11.7 2.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Zn_clus PF00172.13 ETS65380.1 - 0.0087 15.9 10.0 0.017 15.0 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_8 PF13188.1 ETS65380.1 - 0.032 14.1 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS PF00989.19 ETS65380.1 - 0.046 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold LCM PF04072.9 ETS65381.1 - 4.8e-18 65.3 0.0 8.3e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Scs3p PF10261.4 ETS65382.1 - 5.4e-62 208.9 0.9 6.8e-62 208.6 0.6 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Ribosomal_S17 PF00366.15 ETS65384.1 - 1.6e-16 60.1 0.2 2.3e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 B-block_TFIIIC PF04182.7 ETS65385.1 - 2.2e-12 46.6 0.0 8.5e-12 44.7 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR PF01047.17 ETS65385.1 - 0.0076 15.9 0.0 1.1 8.9 0.0 2.7 2 0 0 2 2 2 2 MarR family F-box-like PF12937.2 ETS65386.1 - 5.6e-10 38.7 0.6 1.4e-09 37.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 ETS65386.1 - 1.9e-06 27.5 0.2 0.079 12.8 0.0 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat F-box PF00646.28 ETS65386.1 - 3.3e-06 26.6 0.1 9e-06 25.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain Ribosomal_L28e PF01778.12 ETS65387.1 - 2.4e-35 121.4 1.9 2.9e-35 121.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Hydrophobin PF01185.13 ETS65388.1 - 1.7e-15 57.2 12.0 2.6e-15 56.6 8.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin ApoO PF09769.4 ETS65389.1 - 7.4e-32 110.2 0.3 7.4e-32 110.2 0.2 2.2 2 1 1 3 3 3 1 Apolipoprotein O PMC2NT PF08066.7 ETS65389.1 - 0.053 13.8 0.1 0.094 13.0 0.1 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain ATP-synt_B PF00430.13 ETS65389.1 - 0.1 12.3 5.7 0.11 12.2 2.9 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF972 PF06156.8 ETS65390.1 - 0.0059 16.9 4.4 0.0094 16.2 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Med9 PF07544.8 ETS65390.1 - 0.011 15.4 5.1 0.024 14.3 3.5 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.10 ETS65390.1 - 0.041 13.7 1.4 0.041 13.7 1.0 2.5 2 0 0 2 2 2 0 Basic region leucine zipper DUF4470 PF14737.1 ETS65390.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Mod_r PF07200.8 ETS65390.1 - 0.14 12.0 7.9 0.23 11.3 5.5 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.7 ETS65390.1 - 0.22 11.9 7.9 0.47 10.8 5.5 1.5 1 0 0 1 1 1 0 SlyX ECM11 PF15463.1 ETS65390.1 - 0.83 9.9 7.9 7.6 6.8 5.5 2.5 1 1 0 1 1 1 0 Extracellular mutant protein 11 IncA PF04156.9 ETS65390.1 - 2 7.9 8.6 3 7.4 6.0 1.2 1 0 0 1 1 1 0 IncA protein PAP_assoc PF03828.14 ETS65391.1 - 1.5e-14 53.6 0.1 3.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETS65391.1 - 3.5e-05 24.0 0.0 8.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 ETS65392.1 - 5.8e-50 169.8 0.0 8.2e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65392.1 - 3.6e-35 121.2 0.0 5.6e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 ETS65392.1 - 6.4e-08 32.8 0.0 2.8e-07 30.8 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 ETS65392.1 - 0.0002 20.4 0.0 0.00052 19.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 ETS65392.1 - 1.1 8.0 0.0 1.6 7.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 UBA_4 PF14555.1 ETS65395.1 - 2.3e-10 39.8 0.0 5.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 ETS65395.1 - 4.3e-06 25.8 9.3 0.0097 15.4 1.0 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif UCH PF00443.24 ETS65395.1 - 0.012 14.7 0.0 0.086 11.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 ETS65395.1 - 0.091 12.6 0.1 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain S4 PF01479.20 ETS65396.1 - 7.7e-13 47.6 0.0 1.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 ETS65396.1 - 0.04 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 S4 domain Rtf2 PF04641.7 ETS65396.1 - 0.9 8.6 6.0 1.7 7.7 4.1 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Sigma70_ner PF04546.8 ETS65396.1 - 4.9 6.7 12.4 9 5.8 8.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region S-AdoMet_synt_C PF02773.11 ETS65397.1 - 3.9e-74 246.9 0.5 7.1e-74 246.0 0.3 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 ETS65397.1 - 2.6e-48 162.9 0.0 5e-48 161.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 ETS65397.1 - 6.5e-44 148.2 0.2 6.5e-44 148.2 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain MFS_1 PF07690.11 ETS65398.1 - 9.4e-37 126.5 54.9 5.4e-25 87.8 17.4 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily CN_hydrolase PF00795.17 ETS65399.1 - 7.8e-23 80.7 0.0 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 ETS65400.1 - 2.2e-14 52.9 36.4 2.2e-14 52.9 25.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily HNH_3 PF13392.1 ETS65401.1 - 3.2e-08 32.8 0.4 0.0034 16.7 0.0 2.5 2 0 0 2 2 2 2 HNH endonuclease PsbW PF07123.7 ETS65401.1 - 3.1 7.8 7.0 1.2 9.1 0.2 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre W protein (PsbW) AA_permease PF00324.16 ETS65402.1 - 1.4e-114 383.0 48.5 1.7e-114 382.8 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS65402.1 - 1.2e-32 113.0 52.5 1.7e-32 112.4 36.3 1.3 1 1 0 1 1 1 1 Amino acid permease ALS_ss_C PF10369.4 ETS65403.1 - 3.8e-22 77.8 0.1 1.7e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 ETS65403.1 - 1.2e-11 43.8 0.0 2.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 ETS65403.1 - 7.5e-08 32.0 0.1 3e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 ACT domain SoxG PF04268.7 ETS65403.1 - 0.063 13.1 1.1 0.091 12.6 0.2 1.6 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family Pkinase PF00069.20 ETS65405.1 - 3.6e-57 193.4 0.0 3.7e-56 190.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65405.1 - 3e-27 95.3 0.0 1.9e-26 92.7 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.1 ETS65405.1 - 2.7e-06 27.2 0.0 2.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 PH domain Kdo PF06293.9 ETS65405.1 - 1.8e-05 23.8 0.1 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETS65405.1 - 8.8e-05 21.6 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS65405.1 - 0.0029 17.3 0.0 0.0092 15.7 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sec_GG PF07549.9 ETS65405.1 - 0.12 11.6 0.1 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif YrbL-PhoP_reg PF10707.4 ETS65405.1 - 0.54 9.5 0.0 1 8.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Sugar_tr PF00083.19 ETS65406.1 - 2.1e-123 412.2 22.8 2.4e-123 412.0 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS65406.1 - 1.4e-21 76.6 38.0 1.2e-15 57.1 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_18 PF12847.2 ETS65407.1 - 9.2e-05 22.9 0.4 0.016 15.7 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS65407.1 - 0.00011 22.6 0.4 0.00081 19.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS65407.1 - 0.0058 16.2 0.0 0.02 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Med1 PF10744.4 ETS65407.1 - 0.008 14.9 0.0 0.016 13.9 0.0 1.4 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Methyltransf_23 PF13489.1 ETS65407.1 - 0.0082 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS65407.1 - 0.048 14.0 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 ETS65408.1 - 5.1e-16 57.8 7.7 6.8e-06 25.7 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nop14 PF04147.7 ETS65409.1 - 0.0033 15.4 31.8 0.0061 14.5 22.0 1.3 1 0 0 1 1 1 1 Nop14-like family CDC27 PF09507.5 ETS65409.1 - 0.0051 16.0 23.5 0.0051 16.0 16.3 3.0 3 0 0 3 3 3 1 DNA polymerase subunit Cdc27 Adaptin_binding PF10199.4 ETS65409.1 - 0.012 15.9 13.2 0.074 13.3 7.6 2.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SDA1 PF05285.7 ETS65409.1 - 0.013 14.7 27.8 0.023 13.9 19.3 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 ETS65409.1 - 0.11 10.5 22.6 0.2 9.6 15.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 ETS65409.1 - 0.28 8.8 0.7 0.37 8.4 0.5 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 ETS65409.1 - 0.31 11.0 9.4 0.95 9.4 6.5 1.9 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.1 ETS65409.1 - 0.64 9.4 5.9 1 8.7 4.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 ETS65409.1 - 3.1 7.1 26.5 6.5 6.0 18.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 ETS65409.1 - 3.8 6.9 19.8 7.4 6.0 13.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_L1 PF00687.16 ETS65410.1 - 9.5e-53 178.7 5.0 1.1e-52 178.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Band_7 PF01145.20 ETS65411.1 - 2.2e-21 76.6 0.4 3.7e-21 75.8 0.3 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family AAA_12 PF13087.1 ETS65412.1 - 1.9e-45 154.7 0.0 2.8e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.6 ETS65412.1 - 1.7e-39 135.2 0.0 2.1e-17 63.1 0.0 3.3 3 0 0 3 3 3 3 DNA replication factor Dna2 Actin PF00022.14 ETS65412.1 - 2e-32 112.1 0.0 8.8e-32 109.9 0.0 2.0 1 1 0 1 1 1 1 Actin AAA_11 PF13086.1 ETS65412.1 - 7.1e-28 97.7 0.0 1.7e-16 60.5 0.0 2.8 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 ETS65412.1 - 1.6e-11 44.1 0.0 5.9e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 ETS65412.1 - 3e-06 26.8 0.0 6.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 ETS65412.1 - 0.00038 20.0 0.1 0.45 9.9 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 ETS65412.1 - 0.00039 20.1 0.2 0.0028 17.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 ETS65412.1 - 0.0052 16.9 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 ETS65412.1 - 0.0058 16.6 3.4 0.19 11.6 0.0 3.8 4 0 0 4 4 3 1 AAA ATPase domain SRP54 PF00448.17 ETS65412.1 - 0.0071 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.9 ETS65412.1 - 0.021 14.4 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Helicase Cas_Cas4 PF01930.12 ETS65412.1 - 0.046 13.6 1.1 0.083 12.8 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function DUF83 ResIII PF04851.10 ETS65412.1 - 0.2 11.4 0.0 0.5 10.1 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C PF13361.1 ETS65412.1 - 0.24 10.8 0.0 0.5 9.7 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 ETS65412.1 - 0.29 10.3 0.0 0.68 9.1 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 ETS65412.1 - 0.48 9.3 0.0 0.9 8.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ACC_epsilon PF13822.1 ETS65413.1 - 0.53 10.6 4.4 7 7.0 0.1 3.0 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit E1-E2_ATPase PF00122.15 ETS65414.1 - 3.9e-52 176.5 8.6 9.9e-52 175.2 6.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS65414.1 - 5.1e-37 127.1 14.4 3.1e-35 121.3 2.3 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS65414.1 - 3.2e-31 109.4 0.0 1.1e-30 107.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS65414.1 - 6.7e-15 54.3 0.0 1.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 ETS65414.1 - 1e-13 51.9 0.1 6.3e-13 49.3 0.0 2.4 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS65414.1 - 3e-09 36.7 0.0 5.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS65414.1 - 0.00019 21.0 0.1 0.00039 20.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4149 PF13664.1 ETS65414.1 - 0.0011 18.9 4.6 0.033 14.2 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF4411 PF14367.1 ETS65414.1 - 0.17 11.6 0.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DUF4270 PF14092.1 ETS65414.1 - 0.22 10.1 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) DUF2231 PF09990.4 ETS65414.1 - 3 8.2 11.6 1.3 9.3 0.6 4.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2231) Ins_P5_2-kin PF06090.7 ETS65415.1 - 1.2e-51 175.5 0.0 1.5e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ribosomal_S3Ae PF01015.13 ETS65416.1 - 1.6e-82 275.5 3.7 1.9e-82 275.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 ETS65416.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ribosomal_S7e PF01251.13 ETS65418.1 - 1.7e-77 259.2 1.8 3.4e-52 176.6 0.1 2.0 2 0 0 2 2 2 2 Ribosomal protein S7e RasGAP PF00616.14 ETS65419.1 - 7.9e-27 94.1 0.0 2.1e-26 92.8 0.0 1.7 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Glyoxalase_3 PF13468.1 ETS65420.1 - 5.3e-24 85.0 0.2 8.8e-23 81.0 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain GYF PF02213.11 ETS65421.1 - 0.00042 19.8 0.0 0.00097 18.6 0.0 1.6 1 0 0 1 1 1 1 GYF domain FUSC PF04632.7 ETS65421.1 - 9.6 4.5 8.3 18 3.5 5.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.20 ETS65422.1 - 1.2e-64 217.9 0.0 1.1e-37 129.5 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETS65422.1 - 1.9e-37 128.7 0.0 8.6e-18 64.3 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 ETS65422.1 - 3.2e-17 62.5 0.1 8e-17 61.2 0.1 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.17 ETS65422.1 - 8.7e-14 51.3 0.0 1.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 ETS65422.1 - 5.4e-10 38.8 3.9 2.5e-09 36.7 0.0 3.0 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Kinase-like PF14531.1 ETS65422.1 - 2.6e-05 23.3 0.0 0.0064 15.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETS65422.1 - 0.0024 17.6 5.1 0.0068 16.1 0.0 3.8 4 0 0 4 4 4 1 Phosphotransferase enzyme family CENP-B_dimeris PF09026.5 ETS65422.1 - 0.041 14.1 10.0 0.059 13.6 1.1 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ycf1 PF05758.7 ETS65422.1 - 0.29 8.7 0.8 0.41 8.3 0.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF1675 PF07897.6 ETS65422.1 - 0.96 9.2 6.6 2.7 7.7 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DPBB_1 PF03330.13 ETS65423.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4243 PF14027.1 ETS65424.1 - 2.4e-67 227.7 4.9 2.4e-67 227.7 3.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4243) DUF3140 PF11338.3 ETS65425.1 - 5.9e-31 106.4 3.8 5.9e-31 106.4 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) Med22 PF06179.7 ETS65425.1 - 1.1e-09 38.2 1.4 1.1e-09 38.2 1.0 2.3 3 0 0 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex Herpes_capsid PF06112.6 ETS65425.1 - 1.4 8.9 13.0 4.3 7.3 5.9 2.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF3237 PF11578.3 ETS65426.1 - 1.1e-30 105.8 0.0 1.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF167 PF02594.11 ETS65426.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 Zn_clus PF00172.13 ETS65427.1 - 1.2e-05 25.1 9.4 2.3e-05 24.1 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.10 ETS65428.1 - 6.2e-51 173.1 1.1 1.9e-25 89.8 0.4 3.6 2 2 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_23 PF13489.1 ETS65428.1 - 0.0016 18.2 0.0 0.0061 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS65428.1 - 0.003 18.0 0.0 0.018 15.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NARP1 PF12569.3 ETS65428.1 - 7.4 5.1 11.0 3.6 6.2 6.1 1.6 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 Trp_repressor PF01371.14 ETS65429.1 - 0.12 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Trp repressor protein DUF924 PF06041.6 ETS65430.1 - 1.6e-48 164.9 0.5 2.1e-48 164.5 0.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Fork_head PF00250.13 ETS65431.1 - 3.7e-15 55.7 0.0 6.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 ETS65431.1 - 0.24 11.5 0.0 2.7 8.1 0.0 2.2 1 1 0 1 1 1 0 FHA domain CDC45 PF02724.9 ETS65431.1 - 4.5 5.1 20.4 8 4.3 14.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2217 PF10265.4 ETS65432.1 - 3.2 6.4 17.2 7.4 5.2 11.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ytp1 PF10355.4 ETS65433.1 - 1.5e-99 332.6 3.1 1.5e-99 332.6 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 ETS65433.1 - 2.2e-24 85.0 0.3 2.2e-24 85.0 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Abhydrolase_3 PF07859.8 ETS65434.1 - 8.8e-23 80.9 0.9 2.5e-22 79.4 0.3 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS65434.1 - 4.3e-13 48.6 0.0 1.8e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) COesterase PF00135.23 ETS65434.1 - 0.016 13.9 0.0 0.25 9.9 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Aminotran_1_2 PF00155.16 ETS65435.1 - 2.7e-74 250.2 0.0 4.5e-74 249.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II SSB PF00436.20 ETS65435.1 - 1.1e-12 47.7 0.0 2.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Single-strand binding protein family Aminotran_5 PF00266.14 ETS65435.1 - 3.4e-08 32.6 0.0 5.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETS65435.1 - 6.4e-05 21.4 0.0 0.00018 19.9 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETS65435.1 - 0.0034 16.4 0.1 0.0071 15.4 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.5 ETS65435.1 - 0.0098 15.8 1.3 0.026 14.4 0.9 1.7 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Ribosomal_L12 PF00542.14 ETS65436.1 - 1.9e-18 66.1 11.4 2.6e-18 65.7 3.4 2.4 2 1 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 ETS65436.1 - 0.0047 17.3 6.6 0.0047 17.3 4.6 2.3 2 1 0 2 2 2 1 60s Acidic ribosomal protein DUF2789 PF10982.3 ETS65436.1 - 0.12 12.4 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) DAO PF01266.19 ETS65437.1 - 8.1e-47 159.8 0.2 9.6e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETS65437.1 - 0.00021 20.5 0.1 0.00096 18.3 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS65437.1 - 0.0019 17.1 0.2 0.0036 16.2 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS65437.1 - 0.0026 18.1 0.1 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS65437.1 - 0.0041 16.0 0.1 0.37 9.6 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS65437.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS65437.1 - 0.017 15.1 0.0 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 ETS65437.1 - 0.042 12.0 0.0 0.089 10.9 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.13 ETS65437.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Snf7 PF03357.16 ETS65438.1 - 1.1e-42 145.3 17.4 1.1e-42 145.3 12.1 2.0 1 1 1 2 2 2 1 Snf7 Atg14 PF10186.4 ETS65438.1 - 0.0051 15.7 6.5 0.0051 15.7 4.5 1.5 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Sfi1_C PF10638.4 ETS65438.1 - 0.043 14.2 1.9 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Spindle body associated protein C-terminus SBDS_C PF09377.5 ETS65438.1 - 0.13 11.9 1.8 0.3 10.7 1.2 1.7 1 1 0 1 1 1 0 SBDS protein C-terminal domain Birna_RdRp PF04197.7 ETS65438.1 - 0.28 9.1 5.9 0.31 9.0 4.1 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) MxiH PF09392.5 ETS65438.1 - 0.61 10.6 5.5 5.4 7.6 3.8 2.5 1 1 0 1 1 1 0 Type III secretion needle MxiH like Ribosomal_60s PF00428.14 ETS65438.1 - 0.76 10.2 9.2 1.2 9.6 1.6 2.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein DUF2450 PF10475.4 ETS65438.1 - 1.7 7.4 7.3 3.9 6.2 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DUF724 PF05266.9 ETS65438.1 - 1.7 8.1 10.0 0.74 9.3 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2229 PF09989.4 ETS65438.1 - 3 7.2 6.0 2.6 7.4 2.7 1.7 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) TMCO5 PF14992.1 ETS65438.1 - 5.9 5.9 12.3 11 5.0 8.5 1.5 1 1 0 1 1 1 0 TMCO5 family RasGEF PF00617.14 ETS65439.1 - 7.7e-52 175.7 0.0 1.5e-51 174.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETS65439.1 - 1.9e-16 60.0 0.1 4.7e-16 58.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif MCM PF00493.18 ETS65440.1 - 1.1e-141 471.3 0.1 1.6e-141 470.9 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS65440.1 - 1.3e-17 64.3 0.0 3.8e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS65440.1 - 4.2e-06 26.0 0.0 0.0014 17.8 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETS65440.1 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETS65440.1 - 0.0044 16.6 0.1 0.017 14.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 ETS65440.1 - 0.016 15.5 0.1 0.047 14.0 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIG PF01833.19 ETS65441.1 - 1.6e-12 47.2 4.2 8.3e-12 44.9 2.9 2.3 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 ETS65441.1 - 3.8e-12 45.3 0.6 3.7e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETS65441.1 - 4.3e-12 46.1 0.0 9.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS65441.1 - 2e-09 37.4 1.7 6.6e-09 35.7 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS65441.1 - 1.3e-07 31.1 0.2 0.0066 16.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETS65441.1 - 3.4e-07 30.5 1.3 3.6e-06 27.3 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Glyco_transf_17 PF04724.8 ETS65442.1 - 7.4e-87 291.6 0.0 9.2e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 SnoaL_4 PF13577.1 ETS65443.1 - 4.1e-09 36.4 0.2 1e-08 35.1 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 ETS65443.1 - 0.077 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.2 ETS65443.1 - 0.13 12.6 0.3 0.22 11.9 0.2 1.3 1 0 0 1 1 1 0 SnoaL-like domain PALP PF00291.20 ETS65444.1 - 2.6e-27 95.8 0.0 4.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 ETS65445.1 - 1.6e-18 66.5 9.1 2.1e-18 66.1 6.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS65445.1 - 4.8e-13 48.4 0.2 5e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS65445.1 - 7.5e-05 21.1 1.5 9.2e-05 20.8 1.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 ETS65445.1 - 0.0021 16.5 0.1 0.0024 16.3 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein