# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MFS_1 PF07690.16 GAK61808.1 - 1e-45 156.3 28.4 1e-45 156.3 28.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK61808.1 - 1.5e-12 47.1 6.0 1.5e-12 47.1 6.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAK61808.1 - 2.5e-08 32.8 1.4 4.3e-08 32.0 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 GAK61808.1 - 0.05 14.1 0.3 0.05 14.1 0.3 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF4231) OATP PF03137.20 GAK61808.1 - 0.46 8.7 6.5 0.16 10.2 2.5 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 GAK61809.1 - 4e-38 131.3 0.0 1e-30 106.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 EthD PF07110.11 GAK61810.1 - 4.7e-13 50.1 0.3 6.7e-13 49.6 0.3 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 GAK61810.1 - 0.0029 18.0 0.2 0.0051 17.3 0.2 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase 8TM_micro PF17028.5 GAK61811.1 - 0.24 11.1 0.0 0.35 10.5 0.0 1.1 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Mito_carr PF00153.27 GAK61812.1 - 7e-67 221.4 5.6 6.3e-24 83.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Diphtheria_T PF02764.14 GAK61812.1 - 0.068 13.2 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Diphtheria toxin, T domain Questin_oxidase PF14027.6 GAK61813.1 - 5.2e-71 239.9 0.4 6.8e-71 239.6 0.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like Tyrosinase PF00264.20 GAK61815.1 - 1.4e-36 126.9 2.2 2.2e-36 126.3 2.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase IBN_N PF03810.19 GAK61817.1 - 2.8e-08 33.6 0.0 3.4e-07 30.1 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 GAK61817.1 - 5.7e-05 21.8 0.0 0.016 13.7 0.0 2.6 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus Urb2 PF10441.9 GAK61817.1 - 0.00091 19.2 0.0 0.08 12.9 0.0 3.6 4 0 0 4 4 4 1 Urb2/Npa2 family HEAT PF02985.22 GAK61817.1 - 0.0034 17.5 2.3 1.9 9.0 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Peptidase_M18 PF02127.15 GAK61818.1 - 2.2e-166 554.0 0.0 2.8e-166 553.6 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Acyltransferase PF01553.21 GAK61818.1 - 4.3e-20 71.7 0.0 9.2e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Peptidase_M42 PF05343.14 GAK61818.1 - 0.0036 16.4 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase MarR PF01047.22 GAK61818.1 - 0.12 12.3 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 MarR family Deltaretro_Tax PF05599.11 GAK61818.1 - 0.16 12.5 1.8 0.48 11.0 1.8 1.8 1 0 0 1 1 1 0 Deltaretrovirus Tax protein PCI PF01399.27 GAK61819.1 - 8.3e-21 74.5 0.8 2e-20 73.3 0.8 1.7 1 0 0 1 1 1 1 PCI domain FmiP_Thoc5 PF09766.9 GAK61819.1 - 0.01 15.1 0.3 0.019 14.3 0.3 1.5 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 E3_UFM1_ligase PF09743.9 GAK61819.1 - 0.038 13.6 0.7 3.5 7.2 0.1 2.1 2 0 0 2 2 2 0 E3 UFM1-protein ligase 1 THOC7 PF05615.13 GAK61819.1 - 0.057 13.7 1.3 8 6.8 0.3 3.2 2 1 1 3 3 3 0 Tho complex subunit 7 TPR_10 PF13374.6 GAK61819.1 - 0.065 13.1 0.1 1.9 8.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAK61820.1 - 3e-26 92.2 33.0 8.7e-26 90.7 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UDPG_MGDP_dh_N PF03721.14 GAK61821.1 - 0.19 11.3 0.0 0.78 9.3 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 GAK61822.1 - 7.4e-27 94.3 0.0 2.4e-14 53.3 0.0 4.1 3 1 1 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK61822.1 - 2.7e-15 56.7 0.0 4.4e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK61822.1 - 0.0013 18.0 0.1 0.64 9.2 0.0 2.6 3 0 0 3 3 3 2 Thi4 family Pyr_redox_3 PF13738.6 GAK61822.1 - 0.01 15.1 0.0 5.7 6.1 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK61822.1 - 0.016 15.4 0.0 3.5 7.9 0.0 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAK61822.1 - 0.029 13.2 0.2 2.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 GAK61822.1 - 0.056 12.1 0.0 11 4.7 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 GAK61822.1 - 0.059 12.9 0.2 14 5.1 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAK61822.1 - 0.2 10.7 0.3 0.9 8.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GARS_A PF01071.19 GAK61823.1 - 6.2e-72 241.4 0.0 9e-72 240.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 GAK61823.1 - 2.8e-32 112.0 0.0 5.8e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 GAK61823.1 - 4.5e-29 101.1 0.0 1.9e-28 99.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 GAK61823.1 - 2.4e-28 98.2 0.6 6.1e-28 96.9 0.6 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 GAK61823.1 - 8.7e-14 51.9 1.0 7.1e-13 49.0 1.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Alba PF01918.21 GAK61823.1 - 0.13 12.1 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Alba Ribosomal_L1 PF00687.21 GAK61824.1 - 3.5e-20 72.6 0.0 1.6e-19 70.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Haspin_kinase PF12330.8 GAK61825.1 - 5.9e-57 193.3 0.0 1.8e-56 191.7 0.0 1.6 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 GAK61825.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAK61825.1 - 0.071 12.5 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain FdhE PF04216.12 GAK61825.1 - 0.33 10.8 4.9 0.13 12.1 0.6 2.4 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation 4HBT_2 PF13279.6 GAK61826.1 - 1.5e-07 31.9 0.0 2.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAK61826.1 - 3.2e-07 30.6 0.0 6.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 GAK61826.1 - 6.4e-06 25.6 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase Abhydrolase_6 PF12697.7 GAK61827.1 - 2.9e-11 44.4 0.2 3.8e-11 44.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK61827.1 - 4.9e-06 26.0 0.1 2.2e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAK61827.1 - 0.0025 17.5 0.1 0.0081 15.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAK61827.1 - 0.0057 16.3 0.2 0.01 15.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase LIP PF03583.14 GAK61827.1 - 0.042 13.2 0.5 0.099 11.9 0.5 1.6 1 0 0 1 1 1 0 Secretory lipase DUF3458 PF11940.8 GAK61827.1 - 0.045 14.2 0.0 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold Peptidase_S9 PF00326.21 GAK61827.1 - 0.15 11.5 2.7 0.59 9.6 0.2 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Myb_DNA-bind_7 PF15963.5 GAK61828.1 - 1.5e-24 85.7 0.0 3.9e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like HMG_box PF00505.19 GAK61828.1 - 2.6e-15 56.6 0.1 7.8e-15 55.1 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAK61828.1 - 4.9e-07 30.2 0.1 1.1e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain Myb_DNA-binding PF00249.31 GAK61828.1 - 1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain CHDNT PF08073.12 GAK61828.1 - 0.089 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF5471 PF17565.2 GAK61828.1 - 6.1 7.2 6.9 56 4.1 2.4 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5471) RRM_1 PF00076.22 GAK61829.1 - 3.9e-13 49.0 0.1 2.9e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK61829.1 - 7.6e-05 22.3 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RCC1_2 PF13540.6 GAK61830.1 - 4.4e-14 51.9 10.7 1.5e-07 31.0 1.9 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAK61830.1 - 3.3e-07 30.8 6.4 0.42 11.3 0.0 5.2 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat CHD5 PF04420.14 GAK61831.1 - 2.6e-44 150.9 3.4 2.6e-44 150.9 3.4 2.2 2 1 0 2 2 2 1 CHD5-like protein DUF4079 PF13301.6 GAK61831.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Zip PF02535.22 GAK61832.1 - 2.4e-25 89.5 29.1 4.9e-22 78.6 29.1 3.2 1 1 0 1 1 1 1 ZIP Zinc transporter Tmemb_55A PF09788.9 GAK61832.1 - 0.079 12.0 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A CAF1C_H4-bd PF12265.8 GAK61833.1 - 3.2e-16 59.3 0.1 8.8e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAK61833.1 - 5.5e-16 58.7 5.7 5.4e-06 27.0 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Raptor_N PF14538.6 GAK61834.1 - 1.4e-60 203.6 0.0 2.3e-60 202.8 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 GAK61834.1 - 4.8e-06 27.2 7.7 1.9 9.5 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 GAK61834.1 - 2.9e-05 24.1 0.0 0.0067 16.5 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 GAK61834.1 - 9.9e-05 22.3 6.5 0.041 14.2 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 GAK61834.1 - 0.068 13.6 0.5 1.2 9.5 0.1 3.3 3 1 0 3 3 3 0 HEAT repeats Cnd1 PF12717.7 GAK61834.1 - 0.16 12.0 0.2 0.57 10.2 0.0 2.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Sugar_tr PF00083.24 GAK61835.1 - 4.3e-12 45.6 0.2 6.3e-12 45.1 0.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK61835.1 - 2.8e-05 23.2 0.7 2.8e-05 23.2 0.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3435 PF11917.8 GAK61836.1 - 0.00091 18.3 0.0 0.0021 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Sugar_tr PF00083.24 GAK61837.1 - 1e-06 27.9 4.0 1.5e-06 27.4 4.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Cupin_8 PF13621.6 GAK61838.1 - 1.3e-12 48.0 0.0 7.2e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 GAK61838.1 - 1.1e-08 35.5 0.0 5.8e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 GAK61838.1 - 0.00074 19.1 0.0 0.0023 17.5 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_1 PF00190.22 GAK61838.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin F-box-like PF12937.7 GAK61838.1 - 0.12 12.3 2.4 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 F-box-like Cupin_2 PF07883.11 GAK61838.1 - 0.18 11.6 0.0 0.84 9.4 0.0 2.0 2 0 0 2 2 2 0 Cupin domain SNF2_N PF00176.23 GAK61839.1 - 1.2e-66 224.9 0.0 1.6e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 GAK61839.1 - 1.9e-29 101.4 0.0 3.6e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 GAK61839.1 - 4.7e-13 49.4 0.0 9.8e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 GAK61839.1 - 6.3e-05 22.8 12.1 0.00011 22.1 12.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 GAK61839.1 - 0.00092 19.3 0.0 0.73 9.8 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 GAK61839.1 - 0.0014 18.9 12.1 0.0024 18.1 12.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAK61839.1 - 0.0083 16.0 13.0 0.014 15.2 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK61839.1 - 0.15 12.1 9.1 0.31 11.1 9.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAK61839.1 - 0.64 9.9 13.2 1.6 8.6 13.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PfkB PF00294.24 GAK61840.1 - 3.1e-64 217.2 4.8 3.5e-64 217.0 4.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAK61840.1 - 2.1e-05 24.0 0.0 5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Fer2_3 PF13085.6 GAK61840.1 - 0.18 11.8 0.1 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TMF_DNA_bd PF12329.8 GAK61841.1 - 0.00042 20.3 10.0 0.00082 19.3 10.0 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 GAK61841.1 - 0.0077 16.7 6.0 0.015 15.7 6.0 1.4 1 0 0 1 1 1 1 Cell division protein ZapB ATG16 PF08614.11 GAK61841.1 - 0.0081 16.4 7.0 0.0089 16.3 7.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 GAK61841.1 - 0.011 16.3 4.8 0.012 16.1 4.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 GAK61841.1 - 0.067 13.6 1.3 3 8.3 0.1 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YlqD PF11068.8 GAK61841.1 - 0.1 13.0 6.8 1.1 9.6 4.5 2.1 1 1 1 2 2 2 0 YlqD protein TMF_TATA_bd PF12325.8 GAK61841.1 - 0.12 12.6 5.5 0.15 12.3 4.1 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF5406 PF17400.2 GAK61841.1 - 0.17 12.3 1.2 0.28 11.6 0.2 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5406) HAUS-augmin3 PF14932.6 GAK61841.1 - 0.35 10.4 7.4 0.41 10.2 7.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DivIC PF04977.15 GAK61841.1 - 1.7 8.4 8.7 1.2 8.9 2.2 2.3 1 1 1 2 2 2 0 Septum formation initiator SKN1 PF03935.15 GAK61842.1 - 1.4e-189 630.7 4.6 1.7e-189 630.4 4.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.6 GAK61842.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Neurensin ERAP1_C PF11838.8 GAK61848.1 - 3.6e-76 256.7 1.1 5.8e-76 256.0 1.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 GAK61848.1 - 8.5e-69 231.4 0.0 1.2e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 GAK61848.1 - 2.1e-42 145.5 1.9 9.5e-39 133.5 0.2 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain AMP-binding PF00501.28 GAK61849.1 - 9.3e-47 159.6 0.0 1.4e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAK61849.1 - 4e-13 49.5 0.5 1e-12 48.2 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 GAK61849.1 - 2.1e-09 36.7 5.7 0.0045 16.7 0.1 7.0 8 0 0 8 8 8 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 GAK61849.1 - 7.7e-05 23.6 2.0 0.031 15.3 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 GAK61849.1 - 0.092 12.5 7.6 4 7.3 0.0 4.8 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase GH3 PF03321.13 GAK61849.1 - 0.11 11.4 0.0 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Carn_acyltransf PF00755.20 GAK61850.1 - 1.7e-195 651.1 0.0 2e-195 650.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MMR_HSR1 PF01926.23 GAK61851.1 - 4e-11 43.0 0.0 1.7e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAK61851.1 - 0.057 13.8 0.3 0.18 12.2 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 GAK61851.1 - 0.08 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 GAK61851.1 - 0.098 12.4 0.3 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Lyase_1 PF00206.20 GAK61852.1 - 4.6e-117 390.9 0.0 6.8e-117 390.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAK61852.1 - 1.5e-19 70.1 1.0 4.1e-18 65.5 0.2 2.6 2 0 0 2 2 2 1 Fumarase C C-terminus PilA4 PF18682.1 GAK61852.1 - 0.077 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Pilin A4 Ima1_N PF09779.9 GAK61853.1 - 1.1e-20 74.9 1.9 1.1e-20 74.9 1.9 2.3 2 0 0 2 2 2 1 Ima1 N-terminal domain Rsm22 PF09243.10 GAK61854.1 - 1.1e-31 110.1 0.2 6.5e-14 51.9 0.0 4.7 4 1 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.6 GAK61854.1 - 0.018 14.8 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain NCBP3 PF10309.9 GAK61855.1 - 9e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 GAK61855.1 - 0.0022 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain Bin3 PF06859.12 GAK61856.1 - 3.2e-30 105.0 0.0 5.7e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 GAK61856.1 - 5.1e-11 42.7 0.0 9.3e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK61856.1 - 2.8e-10 40.2 0.0 7.3e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAK61856.1 - 2.3e-09 37.9 0.0 6.5e-05 23.6 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GAK61856.1 - 3.7e-08 34.0 0.0 0.00012 22.7 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAK61856.1 - 7.2e-07 29.8 0.0 0.02 15.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain CheR PF01739.18 GAK61856.1 - 0.00011 21.7 0.0 0.0019 17.7 0.0 2.1 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 GAK61856.1 - 0.0081 16.2 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAK61856.1 - 0.038 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 GAK61856.1 - 0.12 13.4 0.0 0.38 11.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Heme_oxygenase PF01126.20 GAK61857.1 - 1.8e-25 90.0 0.3 2e-21 76.7 0.1 2.9 2 1 0 2 2 2 2 Heme oxygenase PH PF00169.29 GAK61858.1 - 1.8e-05 25.2 0.0 0.015 15.8 0.0 2.9 2 1 0 2 2 2 2 PH domain TMP_2 PF06791.13 GAK61859.1 - 0.044 13.4 3.7 0.05 13.3 1.3 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein PPR_2 PF13041.6 GAK61860.1 - 1.2e-06 28.6 0.0 6 7.1 0.0 5.4 6 1 1 7 7 7 3 PPR repeat family PPR_long PF17177.4 GAK61860.1 - 0.00035 20.0 0.8 0.015 14.7 0.0 3.1 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAK61860.1 - 0.00041 20.4 0.0 4.6 7.7 0.0 5.0 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.7 GAK61860.1 - 0.0025 17.5 0.0 0.92 9.3 0.0 3.4 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 GAK61860.1 - 0.0029 17.7 0.2 6.6 6.9 0.1 4.4 3 1 2 5 5 5 1 Pentatricopeptide repeat domain NLRC4_HD PF17889.1 GAK61860.1 - 0.082 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 NLRC4 helical domain TPR_14 PF13428.6 GAK61860.1 - 0.1 13.5 13.9 17 6.6 0.0 7.3 7 1 1 8 8 8 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 GAK61860.1 - 0.24 11.9 1.7 1.3e+02 3.1 0.1 3.9 3 0 0 3 3 3 0 B12 binding domain TPR_16 PF13432.6 GAK61860.1 - 2.2 9.0 17.3 40 5.0 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAK61860.1 - 8.9 6.7 8.1 41 4.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L17 PF01196.19 GAK61861.1 - 8.6e-30 103.5 0.2 4.5e-29 101.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L17 PFK PF00365.20 GAK61861.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase PP-binding PF00550.25 GAK61862.1 - 4.2e-14 52.6 0.5 6.1e-14 52.1 0.5 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAK61862.1 - 2.6e-08 34.0 0.7 3.6e-08 33.5 0.7 1.1 1 0 0 1 1 1 1 Acyl-carrier Rav1p_C PF12234.8 GAK61863.1 - 2.7e-211 703.3 0.0 3.7e-211 702.9 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal UQ_con PF00179.26 GAK61864.1 - 7.4e-23 80.8 0.0 1.5e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ras PF00071.22 GAK61865.1 - 1.4e-54 184.1 0.0 1.5e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK61865.1 - 2.3e-21 76.2 0.0 3.2e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK61865.1 - 6.5e-06 25.7 0.0 8.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Haem_degrading PF03928.14 GAK61866.1 - 5.5e-29 100.6 0.0 6.6e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Ribosomal_S28e PF01200.18 GAK61867.1 - 8.9e-23 80.1 0.9 2.6e-22 78.6 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S28e CTP_synth_N PF06418.14 GAK61869.1 - 1.7e-120 401.3 0.0 2.5e-120 400.7 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GAK61869.1 - 1.9e-50 171.3 0.0 1.5e-39 135.8 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.23 GAK61869.1 - 0.039 14.0 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.13 GAK61869.1 - 0.14 11.9 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 zf-Nse PF11789.8 GAK61870.1 - 2e-13 49.9 0.0 3.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 GAK61870.1 - 6.6e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 GAK61870.1 - 0.00033 20.4 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK61870.1 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAK61870.1 - 0.022 14.6 0.1 0.056 13.3 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 GAK61870.1 - 0.037 13.9 0.3 0.067 13.1 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAK61870.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain MukF_M PF17192.4 GAK61870.1 - 0.11 12.2 2.1 0.19 11.5 2.1 1.3 1 0 0 1 1 1 0 MukF middle domain Com_YlbF PF06133.11 GAK61870.1 - 2.6 8.7 6.8 3 8.5 3.0 2.6 2 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA Adaptin_N PF01602.20 GAK61871.1 - 3e-112 375.9 0.0 4.3e-112 375.3 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAK61871.1 - 1.3e-53 181.2 0.4 2.7e-53 180.2 0.4 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GAK61871.1 - 1.8e-34 118.3 0.0 5.7e-34 116.7 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAK61871.1 - 3.9e-17 62.4 0.7 1.2e-09 38.4 0.1 5.6 3 2 3 6 6 6 3 HEAT repeats Cnd1 PF12717.7 GAK61871.1 - 4.1e-06 26.9 5.9 0.23 11.5 0.1 3.8 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAK61871.1 - 9.9e-05 22.3 4.2 6.8 7.2 0.2 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_PBS PF03130.16 GAK61871.1 - 1.3 9.9 4.4 16 6.5 0.1 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat bZIP_2 PF07716.15 GAK61872.1 - 1.3e-09 37.9 12.4 1.3e-09 37.9 12.4 2.8 2 1 1 3 3 3 1 Basic region leucine zipper TSC22 PF01166.18 GAK61872.1 - 0.051 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 GAK61872.1 - 0.08 12.8 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 GAK61872.1 - 0.25 12.0 0.0 0.25 12.0 0.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 GAK61873.1 - 0.0011 19.0 30.8 0.0012 18.8 10.2 23.0 2 2 21 24 24 24 11 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 GAK61873.1 - 0.11 12.1 386.6 0.074 12.6 44.8 16.9 1 1 14 15 15 15 0 Intermediate filament protein PPR_2 PF13041.6 GAK61874.1 - 1.1e-07 31.9 0.0 0.39 10.9 0.0 4.9 4 1 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 GAK61874.1 - 0.0092 16.0 0.0 13 5.9 0.0 4.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain ATP13 PF12921.7 GAK61874.1 - 0.02 14.7 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF737 PF05300.11 GAK61874.1 - 1.1 9.6 16.4 0.093 13.1 11.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Ank_4 PF13637.6 GAK61875.1 - 1.7e-10 41.2 0.0 3.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Torus PF16131.5 GAK61875.1 - 9.8e-08 32.7 9.3 2.7e-06 28.0 0.1 3.4 3 0 0 3 3 3 2 Torus domain Ank_2 PF12796.7 GAK61875.1 - 1.1e-06 29.1 0.1 2.5e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.6 GAK61875.1 - 1.4e-06 28.6 8.2 1.4e-06 28.6 8.2 2.4 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GAK61875.1 - 2.8e-05 23.9 10.6 0.0099 15.8 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAK61875.1 - 0.00016 21.4 4.2 0.00016 21.4 4.2 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger Ank_3 PF13606.6 GAK61875.1 - 0.0022 18.3 0.0 0.052 14.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAK61875.1 - 0.003 17.9 0.3 0.0099 16.3 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat zf_CCCH_4 PF18345.1 GAK61875.1 - 0.0091 16.0 1.1 0.0091 16.0 1.1 2.7 3 0 0 3 3 2 2 Zinc finger domain Ank_5 PF13857.6 GAK61875.1 - 0.015 15.6 0.0 0.054 13.8 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) zf-CCCH_3 PF15663.5 GAK61875.1 - 0.16 12.2 1.2 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family Choline_transpo PF04515.12 GAK61876.1 - 0.5 9.5 7.6 1.4 8.1 7.6 1.6 1 1 0 1 1 1 0 Plasma-membrane choline transporter FoP_duplication PF13865.6 GAK61877.1 - 4.9 7.8 12.0 1.7 9.2 3.9 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.25 GAK61878.1 - 7.1e-48 163.3 0.0 3e-33 115.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK61878.1 - 7.3e-23 81.2 0.2 7.7e-22 77.8 0.0 2.5 3 1 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK61878.1 - 0.0037 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAK61878.1 - 0.025 13.9 0.2 0.037 13.4 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomerase_RBD PF12009.8 GAK61879.1 - 3.1e-40 137.4 0.2 1.7e-39 135.0 0.1 2.3 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 GAK61879.1 - 1.6e-12 47.5 0.0 2.8e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) GHMP_kinases_N PF00288.26 GAK61880.1 - 1.6e-14 53.9 1.9 5.3e-14 52.2 1.9 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAK61880.1 - 4.3e-06 27.0 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal HLH PF00010.26 GAK61881.1 - 0.0012 18.8 0.0 0.0072 16.3 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 GAK61881.1 - 0.13 12.2 8.2 0.007 16.4 3.1 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SET PF00856.28 GAK61882.1 - 1.4e-07 32.0 0.0 1e-05 26.0 0.0 2.6 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.23 GAK61882.1 - 0.0002 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MMM1 PF10296.9 GAK61883.1 - 7e-11 41.7 0.0 3.3e-09 36.3 0.0 2.4 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 RBM1CTR PF08081.11 GAK61883.1 - 7.9 6.6 9.2 2.5 8.3 0.5 3.1 2 0 0 2 2 2 0 RBM1CTR (NUC064) family GDI PF00996.18 GAK61884.1 - 3.4e-209 694.8 0.0 3.9e-209 694.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 GAK61884.1 - 0.0054 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pex14_N PF04695.13 GAK61885.1 - 9.5e-25 88.1 0.5 2.5e-24 86.7 0.1 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Swi5 PF07061.11 GAK61886.1 - 5.4e-14 52.0 0.1 8.4e-14 51.4 0.1 1.3 1 0 0 1 1 1 1 Swi5 FemAB PF02388.16 GAK61886.1 - 0.15 10.9 0.0 0.19 10.6 0.0 1.0 1 0 0 1 1 1 0 FemAB family SNF2_N PF00176.23 GAK61888.1 - 4.8e-63 213.0 0.9 9e-63 212.1 0.9 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 GAK61888.1 - 2e-50 170.7 16.6 2e-50 170.7 16.6 2.6 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 GAK61888.1 - 3.8e-17 62.6 0.0 8.8e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK61888.1 - 1.1e-06 28.7 0.0 2.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAK61888.1 - 0.0091 15.2 0.1 0.0091 15.2 0.1 2.0 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Chorion_S16 PF05836.12 GAK61890.1 - 0.28 11.4 6.5 0.44 10.8 6.5 1.2 1 0 0 1 1 1 0 Chorion protein S16 Shadoo PF14999.6 GAK61890.1 - 0.31 11.1 10.8 0.46 10.6 10.8 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective RhlB PF12300.8 GAK61890.1 - 1.2 9.3 8.4 1.8 8.7 8.4 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Ribosomal_60s PF00428.19 GAK61890.1 - 2.4 8.8 12.0 3.6 8.2 12.0 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zn_clus PF00172.18 GAK61891.1 - 0.00035 20.6 15.1 0.00053 20.0 15.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SF3b10 PF07189.11 GAK61893.1 - 2.4e-33 114.1 0.0 2.8e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ribosomal_L29 PF00831.23 GAK61895.1 - 1.1e-18 66.9 1.9 1.1e-18 66.9 1.9 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein DUF5024 PF16427.5 GAK61895.1 - 0.033 14.5 0.0 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) SieB PF14163.6 GAK61895.1 - 0.096 12.2 0.5 0.23 10.9 0.4 1.7 2 0 0 2 2 2 0 Super-infection exclusion protein B SecE PF00584.20 GAK61896.1 - 4e-10 39.5 0.6 2.6e-05 24.0 0.4 2.2 2 0 0 2 2 2 2 SecE/Sec61-gamma subunits of protein translocation complex Img2 PF05046.14 GAK61897.1 - 4.8e-24 84.4 0.0 8.3e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) MMR_HSR1 PF01926.23 GAK61898.1 - 1.8e-15 57.0 0.3 2.9e-14 53.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK61898.1 - 2.7e-07 30.6 0.1 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAK61898.1 - 1.8e-05 24.3 0.0 9.7e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 GAK61898.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 GAK61898.1 - 0.018 15.1 0.9 0.034 14.2 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Retinin_C PF04527.12 GAK61898.1 - 0.086 13.1 0.3 3.2 8.1 0.2 2.4 2 0 0 2 2 2 0 Drosophila Retinin like protein cobW PF02492.19 GAK61898.1 - 0.15 11.6 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nop14 PF04147.12 GAK61898.1 - 3.1 5.9 11.0 6.3 4.9 11.0 1.4 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 GAK61898.1 - 5.1 7.3 7.9 1.5 9.1 4.5 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated UTP25 PF06862.12 GAK61899.1 - 1e-182 608.1 0.7 1.2e-182 607.9 0.7 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HNF-1_N PF04814.13 GAK61899.1 - 0.88 10.2 6.6 2.2 8.9 6.6 1.7 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PBP1_TM PF14812.6 GAK61900.1 - 7.6 7.0 12.9 0.4 11.1 2.8 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3591 PF12157.8 GAK61901.1 - 3e-185 616.1 1.6 4.8e-185 615.4 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 GAK61901.1 - 0.00022 21.0 3.4 0.00052 19.8 3.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAK61901.1 - 0.24 11.5 1.2 0.54 10.4 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle BLOC1S3 PF15753.5 GAK61901.1 - 0.59 10.3 4.9 1 9.5 3.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF2380 PF09533.10 GAK61901.1 - 4.9 6.7 6.5 1.2 8.8 0.3 2.7 3 0 0 3 3 3 0 Predicted lipoprotein of unknown function (DUF2380) ApbA_C PF08546.11 GAK61902.1 - 1e-36 125.9 0.0 1.7e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAK61902.1 - 4.1e-22 78.5 0.0 3.8e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA SMC_N PF02463.19 GAK61903.1 - 6e-26 91.2 0.0 1.1e-25 90.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAK61903.1 - 6.3e-16 59.0 0.0 5.8e-14 52.6 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GAK61903.1 - 1.5e-10 41.9 31.5 1.5e-10 41.9 31.5 5.4 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 GAK61903.1 - 1.2e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAK61903.1 - 0.00028 20.8 10.9 0.0083 16.0 0.3 3.9 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Tropomyosin PF00261.20 GAK61903.1 - 0.00037 19.9 5.1 0.00037 19.9 5.1 5.6 3 2 2 6 6 6 1 Tropomyosin ABC_tran PF00005.27 GAK61903.1 - 0.0078 16.7 0.1 0.0078 16.7 0.1 5.7 4 1 0 4 4 4 1 ABC transporter FtsK_SpoIIIE PF01580.18 GAK61903.1 - 0.038 13.3 0.0 0.038 13.3 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 GAK61903.1 - 0.086 12.7 0.0 0.45 10.4 0.0 2.3 1 0 0 1 1 1 0 RsgA GTPase EMC3_TMCO1 PF01956.16 GAK61903.1 - 0.36 10.6 6.4 3.7 7.2 0.0 3.7 3 2 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Kelch_5 PF13854.6 GAK61904.1 - 3.8e-32 109.7 8.5 2.8e-07 30.4 0.3 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAK61904.1 - 7.2e-32 109.2 13.4 6.3e-09 35.7 0.4 7.2 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 GAK61904.1 - 1.7e-31 107.9 11.7 1.9e-09 37.6 0.0 7.8 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 GAK61904.1 - 3.8e-29 100.0 10.2 4.7e-11 42.1 0.9 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAK61904.1 - 8.1e-28 95.8 9.4 5.4e-11 42.4 0.5 6.5 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GAK61904.1 - 6.6e-22 76.6 13.1 2.6e-06 27.2 0.3 7.1 6 1 0 6 6 6 5 Kelch motif THOC7 PF05615.13 GAK61904.1 - 0.0083 16.4 11.7 0.0083 16.4 11.7 7.1 2 2 2 6 6 6 1 Tho complex subunit 7 DNA_Packaging PF11053.8 GAK61904.1 - 0.083 12.7 1.0 12 5.8 0.0 2.9 2 0 0 2 2 2 0 Terminase DNA packaging enzyme FlaC_arch PF05377.11 GAK61904.1 - 3.2 8.2 30.0 3.7 8.0 2.0 6.6 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) EDR1 PF14381.6 GAK61904.1 - 9.6 5.9 6.3 21 4.7 2.2 2.5 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 zf-C2H2_4 PF13894.6 GAK61906.1 - 0.042 14.7 1.1 0.13 13.1 1.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.15 GAK61906.1 - 0.05 13.6 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 BED zinc finger CDV3 PF15359.6 GAK61906.1 - 0.24 11.9 4.9 0.42 11.1 3.4 2.3 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 TLD PF07534.16 GAK61908.1 - 1.3e-28 100.0 0.0 4e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 TLD RhoGEF PF00621.20 GAK61909.1 - 4e-41 141.3 0.0 6.1e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 GAK61909.1 - 1.1e-10 41.1 8.0 2.8e-05 23.8 0.2 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAK61909.1 - 1.4e-08 34.9 3.1 3.2e-05 24.2 0.8 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAK61909.1 - 0.015 15.7 7.0 4.3 8.3 0.4 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat MMS1_N PF10433.9 GAK61911.1 - 2.8e-152 507.8 0.0 6.4e-152 506.6 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAK61911.1 - 1.5e-90 303.8 0.2 1.8e-89 300.2 0.1 2.6 3 0 0 3 3 3 1 CPSF A subunit region MASE2 PF05230.11 GAK61912.1 - 0.0017 18.4 0.4 0.0044 17.1 0.4 1.7 1 0 0 1 1 1 1 MASE2 domain DUF4407 PF14362.6 GAK61912.1 - 0.069 12.5 1.0 0.1 12.0 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1240 PF06836.12 GAK61912.1 - 0.13 12.8 0.0 0.13 12.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) Tetraspanin PF00335.20 GAK61912.1 - 3.3 7.4 10.8 11 5.7 10.8 1.9 1 1 0 1 1 1 0 Tetraspanin family MFS_1 PF07690.16 GAK61913.1 - 7.8e-27 94.1 21.6 4.6e-26 91.6 22.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 GAK61913.1 - 0.92 9.9 7.9 1.2 9.5 1.9 3.4 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Lig_chan PF00060.26 GAK61913.1 - 5 6.9 0.0 5 6.9 0.0 3.6 3 1 1 4 4 4 0 Ligand-gated ion channel Utp11 PF03998.13 GAK61914.1 - 9.6e-66 222.2 6.7 1.4e-65 221.6 6.7 1.3 1 0 0 1 1 1 1 Utp11 protein CtaG_Cox11 PF04442.14 GAK61914.1 - 5.1e-56 188.9 0.0 8.6e-56 188.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 SLATT_5 PF18160.1 GAK61914.1 - 0.019 14.3 1.3 1 8.7 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 JAKMIP_CC3 PF16034.5 GAK61914.1 - 0.029 14.3 0.7 0.07 13.1 0.7 1.6 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF5432 PF17497.2 GAK61914.1 - 0.17 12.0 0.2 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5432) ORC4_C PF14629.6 GAK61916.1 - 1.2e-45 155.5 0.0 1.8e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 GAK61916.1 - 6.9e-23 81.9 0.3 6.9e-23 81.9 0.3 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAK61916.1 - 3.9e-06 27.3 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAK61916.1 - 5e-05 23.6 0.0 0.00062 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAK61916.1 - 0.00015 21.5 0.2 0.00041 20.0 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 GAK61916.1 - 0.00036 19.8 0.0 0.00059 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAK61916.1 - 0.00055 19.5 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 GAK61916.1 - 0.0053 16.5 0.1 0.016 14.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK61916.1 - 0.032 14.6 0.1 0.12 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAK61916.1 - 0.071 13.6 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 GAK61916.1 - 0.12 12.6 0.0 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAK61916.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 GAK61916.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF4914 PF16260.5 GAK61916.1 - 0.22 9.6 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) SNF2_N PF00176.23 GAK61917.1 - 4.1e-51 173.7 0.0 6.8e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK61917.1 - 1.1e-20 74.0 0.0 2.8e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK61917.1 - 2.3e-06 27.7 0.0 5.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zf_RING PF16744.5 GAK61917.1 - 4.6e-05 23.4 1.4 4.6e-05 23.4 1.4 2.9 3 0 0 3 3 3 1 KIAA1045 RING finger HDA2-3 PF11496.8 GAK61917.1 - 0.00011 21.6 0.0 0.00033 19.9 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 GAK61917.1 - 0.0016 18.1 10.7 0.17 11.5 0.5 3.9 3 1 1 4 4 4 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.24 GAK61917.1 - 0.013 15.4 0.3 0.074 13.0 0.1 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 GAK61917.1 - 0.053 13.4 11.8 0.04 13.8 2.0 3.1 3 0 0 3 3 3 0 PHD-finger AAA_19 PF13245.6 GAK61917.1 - 0.13 12.6 0.0 0.5 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain PHD_4 PF16866.5 GAK61917.1 - 0.58 10.3 15.9 0.32 11.1 1.6 4.7 4 0 0 4 4 4 0 PHD-finger C1_1 PF00130.22 GAK61917.1 - 3.7 7.5 12.6 2.5 8.0 0.0 3.4 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac_C PF08542.11 GAK61918.1 - 1.4e-26 92.7 0.0 3.7e-26 91.4 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAK61918.1 - 1.1e-12 48.0 0.0 1.8e-10 40.8 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 GAK61918.1 - 1.4e-12 48.2 0.4 3.1e-12 47.1 0.0 1.8 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAK61918.1 - 1.1e-06 29.1 0.1 0.00021 21.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 GAK61918.1 - 3.1e-06 27.2 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GAK61918.1 - 1.8e-05 24.6 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAK61918.1 - 3.8e-05 24.0 0.0 0.049 13.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 GAK61918.1 - 0.00036 20.5 0.0 0.00073 19.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 GAK61918.1 - 0.00061 19.6 0.0 0.00096 19.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 GAK61918.1 - 0.00064 19.5 0.0 0.0025 17.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAK61918.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAK61918.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAK61918.1 - 0.0083 15.5 0.0 0.16 11.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 GAK61918.1 - 0.012 15.5 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.6 GAK61918.1 - 0.022 14.6 0.0 0.034 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain MipZ PF09140.11 GAK61918.1 - 0.044 13.1 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ DUF1302 PF06980.11 GAK61918.1 - 0.053 12.1 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) B12-binding_2 PF02607.17 GAK61918.1 - 0.054 14.0 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 B12 binding domain MeaB PF03308.16 GAK61918.1 - 0.076 12.0 0.0 0.19 10.7 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_assoc_2 PF16193.5 GAK61918.1 - 0.083 13.2 0.0 0.23 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA C-terminal domain NTPase_1 PF03266.15 GAK61918.1 - 0.12 12.3 0.1 0.71 9.8 0.1 2.0 1 1 1 2 2 2 0 NTPase DEAD PF00270.29 GAK61918.1 - 0.12 12.2 0.2 0.82 9.4 0.1 2.3 1 1 2 3 3 3 0 DEAD/DEAH box helicase DUF5119 PF17145.4 GAK61918.1 - 0.13 12.2 0.0 0.79 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) AAA_19 PF13245.6 GAK61918.1 - 0.15 12.4 0.1 3.1 8.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain SgrR_N PF12793.7 GAK61918.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term LAP1C PF05609.12 GAK61919.1 - 0.13 11.3 8.9 0.21 10.6 8.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SOG2 PF10428.9 GAK61919.1 - 5 6.2 32.9 8.1 5.5 32.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 GAK61919.1 - 6.8 6.5 6.4 20 5.0 6.4 1.7 1 1 0 1 1 1 0 Rifin TFIIA PF03153.13 GAK61919.1 - 9.1 6.2 18.5 16 5.4 18.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP2 PF01569.21 GAK61920.1 - 5.5e-11 42.4 10.9 2.1e-10 40.5 8.5 2.7 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 GAK61920.1 - 0.00014 22.0 0.8 0.0019 18.3 0.2 2.6 2 0 0 2 2 2 1 Divergent PAP2 family DUF2614 PF11023.8 GAK61920.1 - 0.074 13.1 0.2 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ferritin_2 PF13668.6 GAK61921.1 - 6.1e-41 139.8 2.6 1.2e-40 138.8 2.6 1.5 1 0 0 1 1 1 1 Ferritin-like domain PAXNEB PF05625.11 GAK61922.1 - 3.3e-42 144.9 0.0 2.4e-40 138.9 0.0 3.0 1 1 0 1 1 1 1 PAXNEB protein DLEU7 PF15760.5 GAK61922.1 - 2.6 7.5 8.0 3.5 7.1 2.7 2.3 2 0 0 2 2 2 0 Leukemia-associated protein 7 Aldo_ket_red PF00248.21 GAK61923.1 - 1.3e-54 185.4 0.0 1.6e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2764 PF10962.8 GAK61923.1 - 0.12 11.9 0.0 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2764) Pkinase PF00069.25 GAK61924.1 - 1.5e-71 240.9 0.0 2.4e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK61924.1 - 5.8e-49 166.7 0.0 9.1e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK61924.1 - 0.0012 17.8 0.3 0.003 16.4 0.0 1.8 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAK61924.1 - 0.0021 17.4 0.0 0.0056 16.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like CBF PF03914.17 GAK61924.1 - 0.074 13.1 1.0 11 6.0 0.1 2.9 2 0 0 2 2 2 0 CBF/Mak21 family Sugar_tr PF00083.24 GAK61925.1 - 2.5e-106 356.3 9.8 3e-106 356.0 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK61925.1 - 2.2e-23 82.8 19.9 2.2e-23 82.8 19.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAK61925.1 - 0.0035 16.0 3.5 0.0035 16.0 3.5 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein Complex1_51K PF01512.17 GAK61927.1 - 2.7e-49 167.0 0.0 4.1e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GAK61927.1 - 1.5e-30 105.1 0.1 3.1e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GAK61927.1 - 1.7e-07 31.0 0.0 3.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Tetraspanin PF00335.20 GAK61928.1 - 2 8.1 6.8 3.9 7.1 6.8 1.5 1 1 0 1 1 1 0 Tetraspanin family zf-Tim10_DDP PF02953.15 GAK61929.1 - 3.6e-22 77.8 0.3 4.7e-22 77.4 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RRM_1 PF00076.22 GAK61930.1 - 1.5e-10 40.7 0.0 2e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPL4 PF05021.15 GAK61932.1 - 5.3e-109 364.3 0.0 7.4e-109 363.8 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 GAK61932.1 - 5.4e-66 221.2 1.0 9.5e-66 220.4 1.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.18 GAK61932.1 - 0.00032 19.9 1.9 0.00032 19.9 1.9 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others UN_NPL4 PF11543.8 GAK61932.1 - 0.00086 19.7 0.0 0.0028 18.1 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 DUF5572 PF17733.1 GAK61932.1 - 0.02 14.8 1.2 0.052 13.4 1.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5572) ABC_membrane PF00664.23 GAK61933.1 - 3.1e-64 217.3 27.2 3.6e-32 112.1 12.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK61933.1 - 4.2e-55 186.0 0.1 4e-30 105.1 0.0 3.6 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 GAK61933.1 - 3.5e-10 39.7 0.2 0.00082 18.9 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAK61933.1 - 8.4e-07 29.1 0.4 0.46 10.2 0.1 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAK61933.1 - 1.7e-06 28.1 0.8 0.012 15.7 0.2 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAK61933.1 - 1e-05 25.2 0.9 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK61933.1 - 1.5e-05 25.4 0.0 0.048 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAK61933.1 - 8.3e-05 22.5 1.3 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 GAK61933.1 - 0.00063 19.8 3.2 0.29 11.2 0.1 2.9 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.6 GAK61933.1 - 0.0007 20.1 5.6 0.45 11.0 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GAK61933.1 - 0.011 15.5 0.1 6.6 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAK61933.1 - 0.017 14.4 0.5 5.5 6.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 GAK61933.1 - 0.023 15.0 1.2 13 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 GAK61933.1 - 0.023 14.4 0.1 5.5 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 GAK61933.1 - 0.027 14.0 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 GAK61933.1 - 0.027 14.7 0.1 6 7.1 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAK61933.1 - 0.033 13.8 0.9 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 GAK61933.1 - 0.037 13.1 1.3 4.4 6.3 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 GAK61933.1 - 0.039 13.5 1.4 1.6 8.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 GAK61933.1 - 0.039 13.7 0.9 2.4 7.9 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 GAK61933.1 - 0.06 12.7 1.0 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 GAK61933.1 - 0.075 12.9 0.5 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 GAK61933.1 - 0.077 12.7 0.5 23 4.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein MeaB PF03308.16 GAK61933.1 - 0.085 11.8 0.7 0.56 9.1 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 GAK61933.1 - 0.1 12.7 2.0 0.73 9.9 0.5 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 GAK61933.1 - 0.16 11.1 0.2 6.1 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 GAK61933.1 - 0.18 11.0 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 GAK61933.1 - 0.27 11.4 3.3 24 5.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain PA28_beta PF02252.18 GAK61934.1 - 2.6e-48 163.4 0.1 3.9e-48 162.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 GAK61934.1 - 0.0072 16.3 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Sec5 PF15469.6 GAK61935.1 - 7.8e-54 182.4 0.0 1.6e-53 181.3 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 GAK61935.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Vps51/Vps67 Exo84_C PF16528.5 GAK61935.1 - 0.14 12.0 0.2 0.58 9.9 0.0 2.0 2 0 0 2 2 2 0 Exocyst component 84 C-terminal Tim17 PF02466.19 GAK61936.1 - 1.5e-32 112.3 4.7 2.1e-32 111.8 4.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 GAK61936.1 - 0.18 11.9 8.5 0.36 11.0 0.3 2.8 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III Pyr_redox_2 PF07992.14 GAK61937.1 - 5.6e-12 45.5 0.0 2.7e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAK61937.1 - 3.4e-11 42.9 0.0 1.2e-07 31.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 GAK61937.1 - 3.8e-10 38.8 0.8 4.2e-09 35.4 0.8 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAK61937.1 - 7.1e-10 39.0 0.0 1.9e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAK61937.1 - 8.5e-10 38.4 0.4 6.5e-06 25.6 0.1 3.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK61937.1 - 5.5e-08 32.8 0.1 2e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK61937.1 - 9.8e-06 25.6 0.0 0.017 15.1 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAK61937.1 - 3.7e-05 22.9 0.1 0.092 11.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 GAK61937.1 - 0.00035 19.9 0.0 0.014 14.7 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 GAK61937.1 - 0.0074 16.8 0.0 0.21 12.2 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAK61937.1 - 0.014 14.3 0.7 0.099 11.5 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 GAK61937.1 - 0.025 13.7 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 GAK61937.1 - 0.036 14.1 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mqo PF06039.15 GAK61937.1 - 0.16 10.5 0.0 0.58 8.6 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 GAK61937.1 - 0.23 10.7 0.5 13 5.0 0.2 2.7 2 1 0 3 3 3 0 FAD binding domain Hepar_II_III PF07940.13 GAK61938.1 - 5.5e-10 39.3 0.5 1.3e-09 38.1 0.5 1.6 1 0 0 1 1 1 1 Heparinase II/III-like protein Arc_PepC_II PF06847.11 GAK61938.1 - 0.098 13.2 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II GATA PF00320.27 GAK61939.1 - 1.6e-13 50.0 5.4 2.9e-13 49.2 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PPR_2 PF13041.6 GAK61940.1 - 1.6e-09 37.8 0.0 0.00054 20.1 0.0 6.9 7 1 0 7 7 7 1 PPR repeat family PPR PF01535.20 GAK61940.1 - 4.5e-08 32.8 1.3 0.037 14.3 0.0 6.0 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 GAK61940.1 - 0.0004 20.0 0.1 2.3 8.0 0.0 4.5 4 0 0 4 4 4 2 PPR repeat TPR_14 PF13428.6 GAK61940.1 - 0.014 16.2 11.9 41 5.4 0.5 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 GAK61941.1 - 1.1e-32 111.5 13.8 1.5e-06 28.8 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK61941.1 - 5.3e-13 49.1 0.0 0.0018 18.5 0.1 5.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain 4HBT_2 PF13279.6 GAK61941.1 - 5.4e-11 43.1 0.1 1.6e-10 41.6 0.1 1.8 2 0 0 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.22 GAK61941.1 - 0.0045 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 GAK61941.1 - 0.011 15.1 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Acyl-ACP thioesterase WD40_like PF17005.5 GAK61941.1 - 0.015 14.6 0.0 2.3 7.5 0.0 2.8 1 1 1 2 2 2 0 WD40-like domain zf-C2H2 PF00096.26 GAK61944.1 - 0.046 14.2 0.6 0.11 13.0 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type ADH_zinc_N PF00107.26 GAK61945.1 - 1.2e-13 51.2 0.4 5.9e-13 48.9 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK61945.1 - 2.4e-10 40.3 0.0 4.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Es2 PF09751.9 GAK61946.1 - 2.4e-99 334.0 7.7 2.4e-99 334.0 7.7 1.3 2 0 0 2 2 2 1 Nuclear protein Es2 ODC_AZ PF02100.17 GAK61947.1 - 7.1e-13 48.5 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme UCH PF00443.29 GAK61948.1 - 2.8e-29 102.4 0.0 4.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAK61948.1 - 5.7e-11 42.6 0.1 1.4e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAK61948.1 - 7.2e-05 22.5 0.0 0.00037 20.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.16 GAK61949.1 - 1.2e-19 70.5 38.7 1.8e-17 63.3 35.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_20 PF00728.22 GAK61950.1 - 3.6e-83 279.9 0.0 5e-83 279.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAK61950.1 - 2.3e-18 67.2 0.0 7e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAK61950.1 - 1.6e-05 25.6 0.0 0.00039 21.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Acyl-CoA_dh_1 PF00441.24 GAK61951.1 - 2.1e-33 115.7 5.1 4.2e-33 114.7 5.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAK61951.1 - 2.2e-19 69.4 0.0 4.6e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAK61951.1 - 2.9e-17 63.3 0.4 1.3e-16 61.3 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAK61951.1 - 1.4e-12 48.0 5.7 1.4e-12 48.0 5.7 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3818 PF12825.7 GAK61952.1 - 1.3e-53 182.3 1.2 5.3e-53 180.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 GAK61952.1 - 4.7e-31 107.5 0.0 1.1e-30 106.3 0.0 1.7 1 0 0 1 1 1 1 PX-associated Pescadillo_N PF06732.11 GAK61953.1 - 1.5e-118 395.3 0.1 1.5e-118 395.3 0.1 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 GAK61953.1 - 8.2e-05 22.9 0.0 0.00027 21.3 0.0 1.9 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Sterol_MT_C PF08498.10 GAK61953.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal GPI-anchored PF10342.9 GAK61954.1 - 2.9e-08 34.4 0.5 2.9e-08 34.4 0.5 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Plasmodium_Vir PF05795.11 GAK61954.1 - 3.4 7.0 4.3 1e+02 2.1 4.8 2.3 2 1 0 2 2 2 0 Plasmodium vivax Vir protein Glyco_hydro_62 PF03664.13 GAK61955.1 - 6.1e-146 484.9 8.0 7.1e-146 484.7 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Pkinase PF00069.25 GAK61957.1 - 9.4e-46 156.3 0.0 2.5e-45 154.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK61957.1 - 4e-25 88.6 0.0 6.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK61957.1 - 0.022 14.7 0.2 0.048 13.6 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CCDC24 PF15669.5 GAK61957.1 - 6.9 6.5 8.4 1.5 8.7 0.4 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family EXOSC1 PF10447.9 GAK61958.1 - 1.2e-22 80.6 0.1 7e-22 78.1 0.1 2.1 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 GAK61958.1 - 0.0034 17.1 0.4 0.026 14.3 0.4 2.4 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region LTV PF04180.14 GAK61959.1 - 5.7e-97 325.9 6.3 5.7e-97 325.9 6.3 2.8 3 0 0 3 3 3 2 Low temperature viability protein Tho2 PF11262.8 GAK61959.1 - 4.3 6.4 5.5 7.8 5.6 5.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Peptidase_M28 PF04389.17 GAK61960.1 - 7.2e-26 91.1 0.1 1e-25 90.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAK61960.1 - 1.2e-08 34.9 0.1 2.5e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 GAK61961.1 - 7.4e-17 61.4 16.2 0.0006 20.6 0.2 7.6 6 1 1 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 GAK61961.1 - 0.047 12.3 0.0 0.3 9.7 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF4278 PF14105.6 GAK61961.1 - 0.059 13.8 0.5 0.13 12.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) Ribosomal_L22e PF01776.17 GAK61962.1 - 9.4e-47 157.9 0.3 1.1e-46 157.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family SSB PF00436.25 GAK61962.1 - 0.082 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Single-strand binding protein family DKCLD PF08068.12 GAK61963.1 - 5.4e-33 112.9 0.1 1.2e-31 108.6 0.2 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 GAK61963.1 - 1.3e-23 84.1 0.3 1.2e-20 74.4 0.3 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAK61963.1 - 8.5e-23 80.3 0.6 1.7e-22 79.4 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 GAK61963.1 - 1.4e-20 73.0 1.4 2.7e-20 72.1 1.4 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 GAK61963.1 - 0.0025 18.0 0.0 0.0066 16.7 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain RNA_polI_A34 PF08208.11 GAK61963.1 - 2.3 8.3 29.0 3.9 7.5 29.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SOBP PF15279.6 GAK61963.1 - 5.1 7.6 8.0 7.9 7.0 8.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein NAD_binding_1 PF00175.21 GAK61965.1 - 1.1e-08 35.7 0.0 0.00039 21.0 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAK61965.1 - 0.015 15.4 0.0 5.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 GAK61965.1 - 0.18 12.2 0.0 0.44 10.9 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain Acyltransferase PF01553.21 GAK61966.1 - 1.6e-22 79.6 0.0 2.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase zf-Tim10_DDP PF02953.15 GAK61967.1 - 1.2e-24 85.7 0.8 1.6e-24 85.3 0.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.11 GAK61967.1 - 0.85 9.6 3.5 0.14 12.2 0.3 1.4 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein ANAPC10 PF03256.16 GAK61968.1 - 2.4e-49 167.5 0.0 3.4e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) MFS_1 PF07690.16 GAK61969.1 - 1.7e-41 142.3 35.3 5.6e-40 137.3 35.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK61969.1 - 4.2e-13 49.0 7.1 4.2e-13 49.0 7.1 2.8 2 1 0 3 3 3 2 Sugar (and other) transporter DUF2613 PF11021.8 GAK61969.1 - 3.8 7.7 5.5 15 5.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) S1 PF00575.23 GAK61970.1 - 2.3e-45 152.8 33.6 2.6e-10 40.5 0.7 9.2 9 0 0 9 9 9 8 S1 RNA binding domain Suf PF05843.14 GAK61970.1 - 8.9e-09 35.7 19.1 2.8e-06 27.5 0.4 4.9 2 1 3 5 5 5 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 GAK61970.1 - 0.0037 17.7 7.9 0.02 15.4 0.3 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAK61970.1 - 0.12 13.3 12.2 4.4 8.4 1.3 5.5 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK61970.1 - 0.27 12.0 3.6 3.4 8.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AdoMet_MTase PF07757.13 GAK61971.1 - 1.1e-34 119.1 0.0 1.9e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 GAK61971.1 - 0.00038 20.5 0.0 0.046 13.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK61971.1 - 0.014 16.1 0.0 0.031 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAK61971.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAK61971.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAK61971.1 - 0.087 13.5 0.0 0.24 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ABC1 PF03109.16 GAK61972.1 - 1.5e-20 73.5 0.0 9.8e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 ABC1 family WD40 PF00400.32 GAK61973.1 - 6.2e-08 33.2 2.0 0.099 13.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Miga PF10265.9 GAK61973.1 - 0.095 11.7 0.8 0.14 11.2 0.8 1.1 1 0 0 1 1 1 0 Mitoguardin Uricase PF01014.18 GAK61974.1 - 2.3e-61 205.8 0.0 4.2e-33 114.4 0.2 2.1 2 0 0 2 2 2 2 Uricase DUF2116 PF09889.9 GAK61976.1 - 0.0036 17.2 0.8 0.0073 16.3 0.8 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ecl1 PF12855.7 GAK61976.1 - 0.019 16.1 20.9 0.019 16.1 20.9 4.5 1 1 2 3 3 3 0 ECL1/2/3 zinc binding proteins RINGv PF12906.7 GAK61977.1 - 1.1e-10 41.5 3.8 2e-10 40.6 3.8 1.5 1 0 0 1 1 1 1 RING-variant domain Cytochrom_C552 PF02335.15 GAK61977.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c552 DEAD PF00270.29 GAK61978.1 - 3.2e-39 134.5 0.1 1.9e-37 128.7 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK61978.1 - 4.4e-19 68.9 0.1 2e-18 66.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAK61978.1 - 0.019 14.2 0.3 0.033 13.4 0.3 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Adaptin_N PF01602.20 GAK61979.1 - 1.8e-151 505.3 6.5 2.1e-151 505.1 6.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 GAK61979.1 - 1.4e-23 83.3 0.7 2.8e-23 82.4 0.7 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 GAK61979.1 - 1.2e-09 38.4 7.9 1.8e-06 28.1 0.7 3.5 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAK61979.1 - 1.8e-06 28.2 4.6 0.95 9.9 0.1 6.4 6 2 2 8 8 8 2 HEAT repeats Peptidase_M73 PF12389.8 GAK61979.1 - 0.0076 16.1 0.2 0.066 13.0 0.1 2.1 2 0 0 2 2 2 1 Camelysin metallo-endopeptidase HEAT PF02985.22 GAK61979.1 - 0.01 16.0 0.8 1.1e+02 3.5 0.0 5.1 4 1 0 4 4 4 0 HEAT repeat DUF5578 PF17741.1 GAK61979.1 - 0.16 11.3 1.2 4 6.8 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5578) TIP120 PF08623.10 GAK61979.1 - 0.36 10.6 6.9 11 5.7 0.2 4.5 3 2 1 4 4 4 0 TATA-binding protein interacting (TIP20) V-ATPase_H_C PF11698.8 GAK61979.1 - 0.58 10.3 3.0 5.8 7.1 0.1 3.5 2 1 1 3 3 3 0 V-ATPase subunit H Hist_deacetyl PF00850.19 GAK61980.1 - 8.8e-82 275.0 0.0 1.2e-81 274.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Nuc_sug_transp PF04142.15 GAK61981.1 - 9.6e-08 31.6 0.1 9.6e-08 31.6 0.1 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.11 GAK61981.1 - 1.6e-06 27.6 8.5 1.6e-06 27.6 8.5 1.5 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 GAK61981.1 - 1.6e-05 24.4 1.3 1.6e-05 24.4 1.3 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 GAK61981.1 - 8.6e-05 22.7 26.2 0.00097 19.3 4.5 3.0 3 1 0 3 3 3 2 EamA-like transporter family HECT PF00632.25 GAK61982.1 - 4.7e-95 318.6 0.1 6.3e-95 318.2 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 GAK61982.1 - 2.1e-34 117.3 18.4 3.6e-12 46.1 2.6 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.30 GAK61982.1 - 2.1e-20 72.9 0.1 5.6e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 C2 domain SlyX PF04102.12 GAK61983.1 - 0.016 15.8 0.1 0.016 15.8 0.1 2.8 3 1 1 4 4 4 0 SlyX E1_FCCH PF16190.5 GAK61983.1 - 0.022 14.9 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain FliJ PF02050.16 GAK61983.1 - 2 8.7 5.8 6.6 7.0 0.1 2.9 3 0 0 3 3 3 0 Flagellar FliJ protein Complex1_LYR PF05347.15 GAK61984.1 - 3.3e-06 27.0 0.1 8.8e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ribosomal_L31 PF01197.18 GAK61984.1 - 0.0019 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 DUF5486 PF17588.2 GAK61984.1 - 0.19 11.7 1.7 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5486) GREB1 PF15782.5 GAK61984.1 - 0.71 6.9 6.6 0.87 6.6 6.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NDUF_C2 PF06374.11 GAK61985.1 - 0.032 14.4 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) RNase_T PF00929.24 GAK61986.1 - 8.1e-11 42.7 0.0 3.3e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Exonuclease SAP PF02037.27 GAK61986.1 - 1.8e-09 37.1 2.6 4.4e-09 35.9 2.6 1.7 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 GAK61986.1 - 0.024 14.4 0.1 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain DUF1389 PF07146.11 GAK61986.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) THDPS_M PF14789.6 GAK61986.1 - 0.12 12.5 0.0 0.49 10.5 0.0 2.1 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle XLF PF09302.11 GAK61986.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.6 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component RRM_1 PF00076.22 GAK61987.1 - 4.6e-07 29.6 0.0 8.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.21 GAK61987.1 - 0.0012 19.0 0.3 0.0029 17.7 0.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger zf_CCCH_4 PF18345.1 GAK61987.1 - 0.065 13.3 0.4 0.16 12.0 0.4 1.7 1 0 0 1 1 1 0 Zinc finger domain RRM_occluded PF16842.5 GAK61987.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif AMPK1_CBM PF16561.5 GAK61988.1 - 2.4e-29 101.4 0.0 4.2e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 GAK61988.1 - 1.6e-28 98.8 0.6 1.6e-28 98.8 0.6 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain MAT1 PF06391.13 GAK61991.1 - 6.3e-44 150.3 17.9 6.3e-44 150.3 17.9 1.4 2 0 0 2 2 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 GAK61991.1 - 6.2e-21 74.0 7.4 1e-20 73.3 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK61991.1 - 0.00015 21.5 7.5 0.00053 19.8 7.7 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK61991.1 - 0.00034 20.4 9.2 0.0017 18.2 9.5 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK61991.1 - 0.0008 19.3 6.8 0.0026 17.7 7.0 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAK61991.1 - 0.0019 18.5 6.3 0.0037 17.5 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 GAK61991.1 - 0.0039 16.9 5.9 0.035 13.9 1.9 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 GAK61991.1 - 0.011 15.6 11.3 0.17 11.7 12.2 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK61991.1 - 0.098 12.5 10.0 0.6 10.0 10.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 GAK61991.1 - 0.11 12.5 5.9 0.35 10.9 5.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 GAK61991.1 - 0.29 11.2 6.9 0.64 10.1 6.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 GAK61991.1 - 0.53 10.5 7.2 11 6.2 3.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 GAK61991.1 - 0.93 9.0 5.2 5.7 6.5 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 GAK61991.1 - 2.7 7.9 5.7 1.5 8.6 1.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 GAK61991.1 - 7.9 6.7 7.6 20 5.4 0.5 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger DUF3797 PF12677.7 GAK61991.1 - 8.2 6.4 7.0 4.3 7.3 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) PIG-U PF06728.13 GAK61992.1 - 1.2e-88 297.7 20.2 2.9e-87 293.2 20.2 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 GAK61992.1 - 0.032 13.9 3.1 0.16 11.7 3.1 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Arf PF00025.21 GAK61993.1 - 3.7e-66 221.9 0.0 4.3e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAK61993.1 - 7.5e-15 54.9 1.1 2.1e-10 40.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAK61993.1 - 1e-11 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAK61993.1 - 1.1e-10 41.3 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAK61993.1 - 9.7e-09 34.9 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 GAK61993.1 - 6.7e-08 32.3 0.0 7.8e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAK61993.1 - 7.7e-08 32.4 0.0 2.4e-07 30.8 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK61993.1 - 0.0068 16.0 0.0 0.085 12.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAK61993.1 - 0.0096 15.5 0.1 0.027 14.0 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MTBP_N PF14918.6 GAK61993.1 - 0.04 13.4 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 MDM2-binding TsaE PF02367.17 GAK61993.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE XS PF03468.14 GAK61993.1 - 0.057 13.7 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 XS domain Glyco_hydro_9 PF00759.19 GAK61994.1 - 6.5e-106 355.2 17.2 7.8e-106 354.9 17.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 VSP PF03302.13 GAK61994.1 - 0.0019 17.1 0.7 0.004 16.1 0.3 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein Ysc84 PF04366.12 GAK61995.1 - 2.8e-40 137.0 0.0 5.8e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 GAK61995.1 - 7.4e-16 57.5 0.1 1.5e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK61995.1 - 1.2e-12 47.5 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAK61995.1 - 1.2e-09 37.7 0.0 2.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.7 GAK61996.1 - 6.9e-06 26.3 14.3 0.026 14.9 0.2 7.1 6 2 1 8 8 8 3 Leucine Rich repeats (2 copies) PPP4R2 PF09184.11 GAK61996.1 - 7.2 6.1 9.3 12 5.4 9.3 1.3 1 0 0 1 1 1 0 PPP4R2 SWIRM-assoc_2 PF16496.5 GAK61996.1 - 8.8 5.1 13.7 13 4.5 13.7 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF2514 PF10721.9 GAK61996.1 - 9 6.3 12.7 19 5.2 12.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Arrestin_N PF00339.29 GAK61998.1 - 0.0093 16.0 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ribosomal_S13_N PF08069.12 GAK61999.1 - 7.4e-32 109.2 0.4 1.4e-31 108.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 GAK61999.1 - 2.9e-14 53.0 0.4 4.4e-14 52.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 GAK61999.1 - 0.0079 16.1 0.1 0.024 14.6 0.0 1.7 1 1 0 2 2 2 1 'Paired box' domain HTH_32 PF13565.6 GAK61999.1 - 0.019 15.6 0.4 0.04 14.5 0.1 1.7 1 1 1 2 2 2 0 Homeodomain-like domain Ribosomal_S6e PF01092.19 GAK62000.1 - 9.3e-55 184.0 0.3 1.9e-54 183.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e TPR_1 PF00515.28 GAK62001.1 - 2.6e-26 90.3 10.9 1.8e-05 24.3 0.0 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAK62001.1 - 4e-23 79.6 6.0 2.3e-06 27.4 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAK62001.1 - 1.5e-19 68.5 17.6 0.00088 19.2 0.1 8.9 10 0 0 10 10 9 5 Tetratricopeptide repeat ANAPC8 PF04049.13 GAK62001.1 - 1.6e-19 70.3 0.0 3.4e-11 43.4 0.0 2.6 2 0 0 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 GAK62001.1 - 9e-12 44.8 17.3 0.00039 21.0 0.1 9.0 5 2 5 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK62001.1 - 4.2e-11 42.9 10.9 0.0049 17.1 0.0 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAK62001.1 - 1e-10 41.7 18.9 8.1e-05 22.8 0.2 7.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAK62001.1 - 6.1e-10 38.8 0.7 0.092 13.2 0.2 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAK62001.1 - 5.3e-09 36.6 17.4 7.2e-09 36.2 1.3 6.1 6 1 2 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK62001.1 - 6.5e-09 36.2 4.8 0.069 13.7 0.1 6.1 6 1 2 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAK62001.1 - 1.7e-08 33.9 12.4 0.71 10.0 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAK62001.1 - 5.1e-08 33.0 17.7 0.001 19.1 0.1 6.2 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAK62001.1 - 1.9e-07 30.6 5.5 1.2e-05 24.9 1.2 3.2 3 0 0 3 3 3 2 TPR repeat TPR_15 PF13429.6 GAK62001.1 - 2.7e-07 30.1 3.0 0.087 12.0 0.0 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAK62001.1 - 2.6e-05 24.6 12.2 0.47 11.2 0.3 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAK62001.1 - 0.022 14.6 16.0 27 4.8 0.1 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat ST7 PF04184.12 GAK62001.1 - 0.088 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 ST7 protein Epimerase PF01370.21 GAK62002.1 - 0.00072 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNase_H PF00075.24 GAK62003.1 - 0.00014 22.1 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 RNase H UQ_con PF00179.26 GAK62004.1 - 8.5e-44 148.6 0.0 1.2e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1691 PF07950.11 GAK62004.1 - 2.1e-06 28.4 3.2 0.0023 18.6 0.3 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) Senescence PF06911.12 GAK62005.1 - 6.6e-49 166.7 7.9 1.3e-48 165.8 7.9 1.5 1 0 0 1 1 1 1 Senescence-associated protein FAD_binding_6 PF00970.24 GAK62006.1 - 9e-34 115.8 0.1 1.5e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAK62006.1 - 8e-31 106.9 0.0 1.2e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAK62006.1 - 6.3e-09 36.1 0.0 5.2e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAK62006.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain RhoGAP PF00620.27 GAK62007.1 - 7.1e-37 126.6 0.0 1.9e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain PI3K_P85_iSH2 PF16454.5 GAK62008.1 - 0.21 11.1 1.3 0.4 10.3 1.3 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_MLP1_2 PF07926.12 GAK62008.1 - 0.33 11.0 3.6 0.8 9.8 3.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 GAK62008.1 - 1.3 9.1 6.4 1.4 9.1 4.6 2.0 1 1 0 1 1 1 0 TolA binding protein trimerisation CENP-W PF15510.6 GAK62009.1 - 8.3e-06 25.9 0.2 1.3e-05 25.3 0.2 1.4 1 1 0 1 1 1 1 CENP-W protein MitMem_reg PF13012.6 GAK62010.1 - 8e-23 81.0 1.5 2e-22 79.7 1.5 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAK62010.1 - 7.8e-16 58.1 0.0 1.4e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FAD_binding_3 PF01494.19 GAK62012.1 - 2.3e-56 191.5 0.1 2.6e-55 188.1 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAK62012.1 - 1.6e-19 70.6 0.0 1.4e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 GAK62012.1 - 1.5e-05 25.1 0.0 4.6e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAK62012.1 - 9.6e-05 21.3 0.0 0.00015 20.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 GAK62012.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK62012.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK62012.1 - 0.0017 17.5 0.1 0.0037 16.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAK62012.1 - 0.0022 17.3 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAK62012.1 - 0.003 16.9 0.1 0.0088 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAK62012.1 - 0.0059 15.7 0.1 0.0084 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 GAK62012.1 - 0.021 15.4 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAK62012.1 - 0.027 14.5 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF1580 PF07618.11 GAK62012.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) UDPG_MGDP_dh_N PF03721.14 GAK62012.1 - 0.091 12.3 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 GAK62012.1 - 0.13 11.9 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 GAK62012.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Nup160 PF11715.8 GAK62013.1 - 5.4e-131 437.9 0.0 8.4e-131 437.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ATP-sulfurylase PF01747.17 GAK62013.1 - 0.073 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP-sulfurylase TPR_8 PF13181.6 GAK62013.1 - 0.087 13.1 0.0 0.48 10.8 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SO_alpha_A3 PF17806.1 GAK62013.1 - 0.11 12.9 0.3 20 5.6 0.0 3.2 3 0 0 3 3 3 0 Sarcosine oxidase A3 domain TPR_19 PF14559.6 GAK62013.1 - 2.7 8.5 10.1 0.83 10.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.21 GAK62014.1 - 1.1e-22 80.3 0.0 2.2e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.11 GAK62014.1 - 0.01 14.0 6.4 0.015 13.4 6.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Abhydrolase_3 PF07859.13 GAK62015.1 - 3.4e-33 115.3 0.0 5.8e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAK62015.1 - 0.00059 19.5 0.0 0.044 13.4 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 GAK62015.1 - 0.0019 17.7 0.0 0.056 12.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAK62015.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 GAK62015.1 - 0.03 13.2 0.0 0.11 11.3 0.0 1.7 1 1 0 1 1 1 0 Carboxylesterase family BAAT_C PF08840.11 GAK62015.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAK62015.1 - 0.062 12.9 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 GAK62015.1 - 0.18 10.5 0.0 0.67 8.6 0.0 1.8 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_M20 PF01546.28 GAK62016.1 - 4.1e-28 98.5 0.0 9.1e-28 97.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAK62016.1 - 5.1e-14 52.1 0.0 1.4e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain EthD PF07110.11 GAK62017.1 - 3.5e-10 40.9 0.4 1.5e-08 35.7 0.1 2.2 2 0 0 2 2 2 1 EthD domain DUF3696 PF12476.8 GAK62017.1 - 0.029 14.8 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) YppF PF14178.6 GAK62017.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 YppF-like protein Mitofilin PF09731.9 GAK62019.1 - 4e-168 561.1 25.1 4.5e-168 560.9 25.1 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Cas_DxTHG PF09455.10 GAK62019.1 - 0.018 14.6 7.5 0.04 13.5 7.5 1.5 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Exonuc_VII_L PF02601.15 GAK62019.1 - 3 7.3 17.1 0.58 9.7 8.7 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit 2Fe-2S_thioredx PF01257.19 GAK62020.1 - 1.4e-59 200.1 0.1 1.8e-59 199.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 GAK62020.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) HTH_30 PF13556.6 GAK62020.1 - 0.16 11.8 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Fer4 PF00037.27 GAK62021.1 - 3e-14 52.2 16.4 2.1e-08 33.6 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GAK62021.1 - 6.8e-13 49.0 10.4 1.1e-12 48.3 10.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAK62021.1 - 3e-10 40.9 8.6 2.5e-05 25.1 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 GAK62021.1 - 2.2e-09 37.3 6.8 0.00017 21.6 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAK62021.1 - 1.3e-08 34.9 21.7 4.4e-06 26.7 12.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAK62021.1 - 1.5e-08 34.7 10.2 2.5e-08 34.0 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAK62021.1 - 1.6e-08 34.9 3.1 0.00022 21.6 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAK62021.1 - 5.9e-07 29.3 17.8 0.00048 20.1 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 GAK62021.1 - 2e-06 27.6 12.5 0.0033 17.4 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GAK62021.1 - 1.6e-05 25.1 11.8 0.00061 20.1 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GAK62021.1 - 0.00019 21.9 10.8 0.036 14.6 12.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 GAK62021.1 - 0.00056 20.4 10.0 0.12 12.9 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 GAK62021.1 - 0.02 15.1 5.3 1.5 9.1 0.4 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 GAK62021.1 - 0.079 13.2 9.0 3 8.1 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 GAK62021.1 - 0.3 12.1 16.3 0.42 11.7 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 GAK62021.1 - 0.48 10.6 6.1 2.5 8.3 0.7 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 GAK62021.1 - 0.61 11.0 11.8 3.9 8.4 1.9 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain EPF PF17181.4 GAK62021.1 - 2.2 8.3 6.9 1.1 9.3 0.8 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins RNase_H2-Ydr279 PF09468.10 GAK62022.1 - 1.6e-07 31.7 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 GAK62022.1 - 6.4e-07 29.5 0.0 1.5e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain VCBS PF13517.6 GAK62023.1 - 5.6e-22 78.1 16.0 6.8e-08 33.0 1.8 6.4 5 1 1 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAK62023.1 - 9.4e-09 35.2 17.7 0.00029 20.9 0.2 6.0 6 0 0 6 6 6 4 FG-GAP repeat V_ATPase_I PF01496.19 GAK62024.1 - 1.2e-303 1009.1 0.0 1.4e-303 1009.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ApoO PF09769.9 GAK62025.1 - 0.1 12.5 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Apolipoprotein O FTA4 PF13093.6 GAK62025.1 - 0.2 11.5 1.3 0.46 10.3 0.0 2.2 3 0 0 3 3 3 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 YtxH PF12732.7 GAK62025.1 - 9.8 6.8 7.1 7.2 7.2 1.1 2.9 2 0 0 2 2 2 0 YtxH-like protein CBM_21 PF03370.13 GAK62026.1 - 6.2e-29 100.5 0.0 1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAK62026.1 - 7e-07 29.7 0.3 1.6e-06 28.6 0.3 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Serglycin PF04360.12 GAK62026.1 - 0.52 10.3 3.8 1.3 9.0 3.8 1.6 1 0 0 1 1 1 0 Serglycin DUF2205 PF10224.9 GAK62028.1 - 2.2e-10 40.4 0.3 2.8e-10 40.0 0.3 1.1 1 0 0 1 1 1 1 Short coiled-coil protein DNA_pol_phi PF04931.13 GAK62029.1 - 0.87 7.6 4.0 1.4 6.9 4.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi ORC_WH_C PF18137.1 GAK62030.1 - 7.6e-28 97.3 1.7 1e-27 96.9 0.0 2.1 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 GAK62030.1 - 1.1e-11 44.5 0.1 0.0002 20.6 0.0 3.3 4 0 0 4 4 4 2 Origin recognition complex (ORC) subunit 3 N-terminus Cytochrom_B562 PF07361.11 GAK62030.1 - 4.4 8.0 7.2 8.2 7.1 1.7 2.7 2 0 0 2 2 2 0 Cytochrome b562 CDP-OH_P_transf PF01066.21 GAK62031.1 - 1.2e-12 48.4 0.7 1.2e-12 48.4 0.7 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4187 PF13821.6 GAK62032.1 - 1.7e-19 69.3 6.8 3.7e-19 68.2 6.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 GAK62032.1 - 4.2e-06 26.5 0.6 9.9e-06 25.4 0.6 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 GAK62032.1 - 0.19 12.1 3.1 0.51 10.7 3.1 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAK62032.1 - 1 10.0 4.9 1.5 9.4 1.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA PF00004.29 GAK62033.1 - 7.3e-42 142.9 0.0 2.4e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK62033.1 - 1.3e-06 28.1 0.1 2.8e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAK62033.1 - 3e-05 24.0 0.1 0.00011 22.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAK62033.1 - 9.7e-05 22.7 0.0 0.0057 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GAK62033.1 - 0.00013 22.4 0.3 0.0027 18.1 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 GAK62033.1 - 0.00024 21.3 0.0 0.00078 19.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAK62033.1 - 0.00083 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAK62033.1 - 0.0035 17.1 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAK62033.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 GAK62033.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAK62033.1 - 0.025 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAK62033.1 - 0.025 14.3 0.1 0.14 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 GAK62033.1 - 0.044 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAK62033.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAK62033.1 - 0.055 13.4 0.0 7.2 6.4 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 GAK62033.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 GAK62033.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAK62033.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 GAK62033.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 GAK62033.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 GAK62033.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAK62033.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 GAK62034.1 - 6.7e-106 352.7 0.0 1.3e-105 351.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAK62034.1 - 4.7e-43 145.9 0.0 8.1e-43 145.1 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAK62034.1 - 2.7e-14 53.4 3.5 5.5e-14 52.4 3.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain VAPB_antitox PF02697.14 GAK62034.1 - 0.14 13.0 0.0 3.4 8.5 0.1 2.8 2 0 0 2 2 2 0 Putative antitoxin DASH_Dad2 PF08654.10 GAK62035.1 - 2.5e-25 88.8 0.0 3.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF3348 PF11828.8 GAK62035.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) SCA7 PF08313.12 GAK62036.1 - 3.8e-30 103.6 0.1 8.1e-30 102.5 0.1 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain BRF1 PF07741.13 GAK62036.1 - 0.046 14.1 4.3 0.089 13.1 0.7 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MAS20 PF02064.15 GAK62036.1 - 0.18 11.9 1.0 0.47 10.5 0.2 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor Exo_endo_phos PF03372.23 GAK62037.1 - 7.6e-12 45.2 0.2 2e-11 43.9 0.2 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 GAK62037.1 - 2.1e-08 34.1 6.6 5.2e-07 29.7 0.3 3.2 2 1 1 3 3 3 2 GRF zinc finger Exo_endo_phos_2 PF14529.6 GAK62037.1 - 0.041 13.7 0.0 1.8 8.4 0.0 2.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Peptidase_M22 PF00814.25 GAK62038.1 - 1.2e-71 241.6 1.0 1.5e-71 241.3 1.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Fcf1 PF04900.12 GAK62040.1 - 3.7e-36 123.5 1.5 5.3e-36 123.0 1.1 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 GAK62040.1 - 9.4e-13 48.5 0.0 6.3e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 PIN like domain Imm-NTF2 PF15655.6 GAK62040.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein Porin_3 PF01459.22 GAK62041.1 - 4.3e-82 275.6 2.6 5e-82 275.4 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin TFIIS_M PF07500.14 GAK62042.1 - 1.4e-24 86.8 1.2 1.4e-24 86.8 1.2 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 GAK62042.1 - 6.8e-12 45.1 8.5 1.1e-11 44.4 8.5 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 GAK62042.1 - 6.8e-08 32.6 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD_2 PF13831.6 GAK62042.1 - 0.0078 15.7 2.9 0.013 15.0 2.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 GAK62042.1 - 2.2 7.9 9.7 0.68 9.5 6.6 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 GAK62043.1 - 6.6e-07 29.6 7.0 1.3e-06 28.6 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAK62043.1 - 0.0011 19.2 5.6 0.0027 18.0 5.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAK62043.1 - 0.0024 17.9 1.6 0.0052 16.8 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAK62043.1 - 0.0048 17.1 3.1 0.012 15.8 3.1 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 GAK62043.1 - 0.029 14.2 0.8 0.057 13.3 0.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 GAK62043.1 - 0.053 13.4 7.6 0.1 12.5 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK62043.1 - 0.37 10.7 7.4 0.77 9.6 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 GAK62043.1 - 0.48 10.8 5.0 0.99 9.8 5.0 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 GAK62043.1 - 0.53 10.4 8.4 0.15 12.2 5.2 1.9 2 0 0 2 2 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 GAK62043.1 - 1.3 8.7 3.0 2.9 7.6 3.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAK62043.1 - 2.2 8.1 5.1 4.3 7.2 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lactamase_B_2 PF12706.7 GAK62044.1 - 0.0044 16.6 2.1 0.032 13.7 0.5 2.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 GAK62044.1 - 0.023 14.1 0.0 0.059 12.8 0.0 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DRMBL PF07522.14 GAK62044.1 - 0.057 13.6 0.0 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase Sde2_N_Ubi PF13019.6 GAK62045.1 - 2.9e-37 128.0 1.0 2.9e-37 128.0 1.0 1.7 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain 5_nucleotid_C PF02872.18 GAK62046.1 - 0.028 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Phosducin PF02114.16 GAK62047.1 - 8.3e-12 44.6 0.0 1.4e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Phosducin GST_N_3 PF13417.6 GAK62047.1 - 1.2e-05 25.6 0.0 3.1e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK62047.1 - 0.00063 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAK62047.1 - 0.0007 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FoP_duplication PF13865.6 GAK62047.1 - 0.028 14.9 1.2 0.028 14.9 1.2 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 GST_C PF00043.25 GAK62047.1 - 0.036 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thioredoxin PF00085.20 GAK62047.1 - 0.19 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin PUF PF00806.19 GAK62049.1 - 2.6e-56 184.2 0.0 1.8e-06 27.3 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat LOB PF03195.14 GAK62049.1 - 0.0059 17.2 0.9 1.4 9.5 0.1 3.2 3 1 0 3 3 3 1 Lateral organ boundaries (LOB) domain DUF4736 PF15883.5 GAK62049.1 - 0.07 12.9 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) FliG_C PF01706.16 GAK62049.1 - 0.081 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 FliG C-terminal domain Alg6_Alg8 PF03155.15 GAK62050.1 - 2.4e-156 521.5 26.5 2.6e-152 508.2 22.2 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family SGS PF05002.15 GAK62051.1 - 2.1e-29 101.4 1.0 3.9e-29 100.6 1.0 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 GAK62051.1 - 2.1e-13 51.1 0.0 3.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 CS domain PTN13_u3 PF16599.5 GAK62051.1 - 0.0072 16.4 1.4 0.011 15.8 0.9 1.5 1 1 1 2 2 2 1 Unstructured linker region on PTN13 protein between PDZ DUF2057 PF09829.9 GAK62051.1 - 0.008 16.4 0.5 0.029 14.5 0.2 1.8 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) DUF896 PF05979.12 GAK62052.1 - 0.39 10.6 0.1 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Pkinase PF00069.25 GAK62053.1 - 4e-65 219.8 0.0 5.1e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62053.1 - 1.3e-28 100.0 0.0 1.7e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAK62053.1 - 5.6e-14 52.6 0.2 5.6e-14 52.6 0.2 3.1 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 GAK62053.1 - 1.1e-08 35.3 0.0 1.5e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 C2 domain Kinase-like PF14531.6 GAK62053.1 - 2e-07 30.6 0.0 1.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAK62053.1 - 0.0027 16.7 0.0 0.0054 15.7 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 GAK62053.1 - 0.0053 16.4 0.1 0.56 9.8 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAK62053.1 - 0.056 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAK62053.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 GAK62054.1 - 4.5e-14 52.0 0.0 3.7e-07 29.9 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK62054.1 - 0.00014 21.9 0.0 0.00035 20.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Fungal_trans_2 PF11951.8 GAK62054.1 - 0.099 11.4 0.2 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SNARE PF05739.19 GAK62055.1 - 2e-15 56.5 0.1 4.2e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 GAK62055.1 - 2.4e-08 33.0 0.0 1.2e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 GAK62055.1 - 7.1e-08 32.4 9.7 0.00019 21.2 0.7 2.3 2 0 0 2 2 2 2 Syntaxin Syntaxin-18_N PF10496.9 GAK62055.1 - 0.00064 19.9 1.6 0.0012 19.0 0.2 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF3829 PF12889.7 GAK62055.1 - 0.003 17.1 4.8 0.11 11.9 0.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3829) DUF4618 PF15397.6 GAK62055.1 - 0.026 13.9 1.5 0.35 10.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Prominin PF05478.11 GAK62055.1 - 0.062 11.3 0.6 0.13 10.2 0.6 1.5 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 GAK62055.1 - 0.086 13.2 1.2 0.38 11.2 1.2 2.2 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3347 PF11827.8 GAK62055.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) DUF148 PF02520.17 GAK62055.1 - 0.21 11.7 7.1 0.2 11.8 0.7 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF1664 PF07889.12 GAK62055.1 - 0.29 11.2 2.8 0.85 9.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 GAK62055.1 - 0.33 11.4 3.1 0.32 11.5 0.5 2.1 2 1 1 3 3 3 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 GAK62055.1 - 0.52 10.6 3.8 1.1 9.6 0.4 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.6 GAK62055.1 - 0.72 10.2 4.8 17 5.7 0.3 2.5 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Cor1 PF04803.12 GAK62055.1 - 0.78 9.9 8.2 14 5.9 0.1 2.4 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Spectrin PF00435.21 GAK62055.1 - 1.2 9.6 4.5 5.5 7.5 0.3 3.3 2 1 1 3 3 3 0 Spectrin repeat SlyX PF04102.12 GAK62055.1 - 1.7 9.4 7.0 0.9 10.2 1.0 3.1 3 1 1 4 4 4 0 SlyX DNA_pol_B_thumb PF14791.6 GAK62056.1 - 9.2e-20 70.6 0.1 2e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 GAK62056.1 - 1.2e-09 38.4 0.0 5e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 GAK62056.1 - 6e-07 29.7 0.1 2.4e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 GAK62056.1 - 0.00033 20.4 0.0 0.0008 19.2 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Abhydrolase_6 PF12697.7 GAK62057.1 - 0.00059 20.5 1.2 0.0014 19.2 1.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAK62057.1 - 0.11 12.2 0.0 0.97 9.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ABC_membrane PF00664.23 GAK62058.1 - 1.2e-40 139.9 6.2 1.5e-40 139.6 6.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAK62058.1 - 2e-35 122.3 0.0 2.4e-34 118.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAK62058.1 - 1.4e-05 24.6 0.0 0.0016 17.9 0.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 GAK62058.1 - 0.001 19.5 0.0 0.0091 16.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 GAK62058.1 - 0.0063 16.4 0.1 0.083 12.7 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAK62058.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAK62058.1 - 0.024 14.4 0.1 0.058 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAK62058.1 - 0.028 14.7 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 GAK62058.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 GAK62058.1 - 0.073 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAK62058.1 - 0.15 12.1 0.0 1 9.4 0.0 2.5 1 1 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 GAK62060.1 - 4.8e-91 305.6 0.0 5.6e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II K-box PF01486.17 GAK62060.1 - 0.16 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 K-box region 2-oxoacid_dh PF00198.23 GAK62062.1 - 2.5e-77 259.5 0.2 3.3e-77 259.1 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAK62062.1 - 1.1e-20 73.2 1.9 1.6e-20 72.7 0.5 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GAK62062.1 - 3.4e-17 62.5 0.4 9.2e-17 61.1 0.4 1.8 1 0 0 1 1 1 1 e3 binding domain SR-25 PF10500.9 GAK62062.1 - 0.00037 20.2 8.5 0.00037 20.2 8.5 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 GAK62062.1 - 0.0038 17.5 1.4 0.0038 17.5 1.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF755) Presenilin PF01080.17 GAK62062.1 - 0.089 11.5 0.8 0.14 10.9 0.8 1.2 1 0 0 1 1 1 0 Presenilin DUF3614 PF12267.8 GAK62062.1 - 1.2 9.6 5.1 3 8.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) Macoilin PF09726.9 GAK62062.1 - 1.4 7.3 3.2 2.3 6.6 3.2 1.4 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 GAK62062.1 - 6.6 5.3 7.9 15 4.1 8.0 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.11 GAK62062.1 - 8.8 4.5 6.4 14 3.9 6.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.32 GAK62064.1 - 1.8e-39 133.0 15.6 1e-06 29.4 0.0 8.8 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK62064.1 - 7e-19 67.9 0.0 3.5e-06 27.2 0.0 5.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GAK62064.1 - 5e-06 26.3 0.3 9.2e-06 25.4 0.3 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 GAK62064.1 - 0.00094 19.1 0.0 0.046 13.6 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAK62064.1 - 0.0039 15.9 0.0 0.38 9.4 0.0 2.8 3 0 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 GAK62064.1 - 0.071 12.4 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Macoilin PF09726.9 GAK62064.1 - 7.2 5.0 17.1 12 4.3 16.6 1.6 2 0 0 2 2 2 0 Macoilin family Ribosomal_S7 PF00177.21 GAK62065.1 - 4.2e-37 127.1 1.6 6.1e-37 126.6 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HAGH_C PF16123.5 GAK62067.1 - 5e-17 62.2 0.0 1.3e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAK62067.1 - 2.7e-12 47.1 1.7 1e-11 45.2 1.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily LRR_6 PF13516.6 GAK62067.1 - 1.9e-07 30.6 0.2 2.9 8.2 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.7 GAK62067.1 - 2.7e-07 30.4 0.1 1e-06 28.5 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAK62067.1 - 3e-05 24.3 2.2 1.6 9.2 0.0 5.8 5 1 2 7 7 7 1 Leucine Rich repeats (2 copies) F-box PF00646.33 GAK62067.1 - 0.00093 19.0 5.0 0.054 13.4 0.7 3.6 2 1 0 2 2 2 1 F-box domain LRR_1 PF00560.33 GAK62067.1 - 6.2 7.8 14.1 1.2e+02 3.9 0.1 5.7 7 0 0 7 7 7 0 Leucine Rich Repeat A_deaminase PF00962.22 GAK62068.1 - 3.5e-33 115.3 0.1 5.3e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Cpn60_TCP1 PF00118.24 GAK62069.1 - 4.3e-160 533.6 1.8 4.9e-160 533.4 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PIP5K PF01504.18 GAK62070.1 - 6.4e-43 146.9 0.1 2.6e-34 118.7 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GAK62070.1 - 2.1e-23 82.7 0.0 3.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GAK62070.1 - 3.8e-15 55.8 10.3 1.1e-14 54.3 10.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger CNDH2_C PF16858.5 GAK62070.1 - 0.12 12.3 3.9 0.27 11.1 3.9 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term IBR PF01485.21 GAK62070.1 - 0.61 10.4 3.9 2.3 8.5 3.9 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Cwf_Cwc_15 PF04889.12 GAK62070.1 - 3.9 7.1 17.0 14 5.3 17.0 2.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DPBB_1 PF03330.18 GAK62071.1 - 2e-05 24.7 0.1 4.1e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Lytic transglycolase SOG2 PF10428.9 GAK62071.1 - 0.0088 15.3 13.5 0.0089 15.3 13.5 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Barwin PF00967.17 GAK62071.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 0 Barwin family Miga PF10265.9 GAK62071.1 - 0.063 12.2 4.1 0.085 11.8 4.1 1.1 1 0 0 1 1 1 0 Mitoguardin CCDC53 PF10152.9 GAK62071.1 - 0.5 10.8 2.6 0.91 9.9 2.6 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Apt1 PF10351.9 GAK62071.1 - 2.2 7.0 11.6 3.1 6.5 11.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Suf PF05843.14 GAK62071.1 - 3.1 7.7 5.5 4.9 7.0 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 GAK62071.1 - 5.1 5.8 6.9 7.4 5.2 6.9 1.2 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.12 GAK62071.1 - 7.2 7.0 13.6 21 5.5 11.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Tmemb_cc2 PF10267.9 GAK62071.1 - 7.7 5.6 5.4 10 5.2 5.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Lin-8 PF03353.15 GAK62071.1 - 7.7 6.0 6.7 11 5.5 6.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 GAK62071.1 - 8.2 3.4 9.4 10 3.1 9.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NIF PF03031.18 GAK62072.1 - 6.2e-22 78.1 0.0 1.8e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase AATF-Che1 PF13339.6 GAK62072.1 - 0.036 14.8 0.6 0.036 14.8 0.6 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor CHAD PF05235.14 GAK62072.1 - 0.13 12.2 8.3 0.11 12.4 4.4 2.7 2 1 0 2 2 2 0 CHAD domain Macoilin PF09726.9 GAK62072.1 - 7.4 5.0 11.4 2.5 6.6 3.0 2.1 2 0 0 2 2 2 0 Macoilin family MMR_HSR1 PF01926.23 GAK62073.1 - 2.4e-14 53.4 0.0 8.5e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK62073.1 - 9.4e-05 22.0 0.0 0.00048 19.7 0.1 2.1 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAK62073.1 - 0.00025 21.0 0.0 0.056 13.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 GAK62073.1 - 0.0018 18.4 0.1 0.0074 16.4 0.1 2.0 2 0 0 2 2 2 1 Dynamin family PNP_UDP_1 PF01048.20 GAK62074.1 - 1.8e-38 132.1 0.3 2.2e-38 131.8 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily SNF2_N PF00176.23 GAK62075.1 - 2.1e-59 201.0 0.0 3.3e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK62075.1 - 1e-11 45.1 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK62075.1 - 3.3e-07 30.5 0.1 9.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 GAK62075.1 - 0.00018 21.3 0.4 0.00062 19.6 0.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK62075.1 - 0.00018 21.4 2.4 0.00021 21.2 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK62075.1 - 0.021 14.8 0.3 0.074 13.1 0.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 GAK62075.1 - 0.025 14.4 1.0 0.071 13.0 1.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAK62075.1 - 0.038 14.3 1.9 0.13 12.6 1.9 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 GAK62075.1 - 0.12 12.2 6.0 0.63 9.9 6.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 GAK62075.1 - 0.15 12.1 1.1 12 6.0 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon CS PF04969.16 GAK62076.1 - 0.01 16.8 0.0 0.043 14.8 0.0 2.0 1 1 0 1 1 1 0 CS domain YmdB PF13277.6 GAK62076.1 - 0.11 11.8 1.2 0.21 10.9 0.6 1.7 2 0 0 2 2 2 0 YmdB-like protein DUF883 PF05957.13 GAK62077.1 - 1.9e-05 25.1 36.3 0.054 14.1 1.8 4.2 1 1 4 5 5 5 5 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GAK62077.1 - 0.017 15.0 33.1 0.49 10.2 2.5 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Phage_Coat_Gp8 PF05371.12 GAK62077.1 - 0.14 11.9 0.3 0.14 11.9 0.3 4.8 5 1 1 6 6 6 0 Phage major coat protein, Gp8 YtxH PF12732.7 GAK62077.1 - 0.15 12.6 38.4 0.16 12.6 3.1 4.6 1 1 2 3 3 3 0 YtxH-like protein Chlorosome_CsmC PF11098.8 GAK62077.1 - 1.1 9.3 32.8 1.1 9.3 3.8 4.3 1 1 2 4 4 4 0 Chlorosome envelope protein C ApoLp-III PF07464.11 GAK62077.1 - 2 8.5 35.4 1.3 9.1 7.8 3.2 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TraG-D_C PF12696.7 GAK62077.1 - 2.5 8.1 11.1 0.042 13.8 1.5 2.6 1 1 2 3 3 3 0 TraM recognition site of TraD and TraG DUF948 PF06103.11 GAK62077.1 - 5 7.4 20.4 2 8.7 0.7 4.7 1 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) REF PF05755.12 GAK62077.1 - 7.4 6.3 25.3 49 3.6 1.1 3.6 1 1 2 3 3 3 0 Rubber elongation factor protein (REF) HA2 PF04408.23 GAK62078.1 - 1.3e-16 60.8 0.0 1.3e-16 60.8 0.0 3.8 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAK62078.1 - 4.3e-15 56.0 0.0 1.3e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK62078.1 - 5.6e-11 42.5 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 GAK62078.1 - 2e-09 37.7 0.1 5.3e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 GAK62078.1 - 2.3e-07 31.1 0.2 1.3e-06 28.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAK62078.1 - 0.021 14.8 0.1 0.068 13.1 0.1 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 GAK62078.1 - 0.042 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 KaiC UTP15_C PF09384.10 GAK62078.1 - 0.044 13.5 0.5 0.14 11.8 0.5 1.8 1 0 0 1 1 1 0 UTP15 C terminal DNA_pol3_gamma3 PF12169.8 GAK62078.1 - 0.046 13.6 0.6 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III AAA_23 PF13476.6 GAK62078.1 - 0.31 11.5 0.0 0.31 11.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain RuvA_C PF07499.13 GAK62078.1 - 0.9 10.0 4.3 1.3 9.5 0.3 3.5 3 2 2 5 5 5 0 RuvA, C-terminal domain Sas10_Utp3 PF04000.15 GAK62080.1 - 3.4e-17 62.8 0.1 9.6e-17 61.4 0.1 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ydc2-catalyt PF09159.10 GAK62080.1 - 0.35 10.6 4.9 0.53 10.0 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SOGA PF11365.8 GAK62080.1 - 2.6 9.2 4.6 33 5.7 0.1 2.9 3 0 0 3 3 3 0 Protein SOGA Ustilago_mating PF05722.12 GAK62081.1 - 1.5e-94 316.7 4.1 2.3e-94 316.2 4.1 1.3 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Homeobox_KN PF05920.11 GAK62081.1 - 2.3e-17 62.6 0.9 1e-16 60.5 0.9 2.2 1 1 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAK62082.1 - 9.5e-13 47.8 1.1 1.4e-12 47.2 0.2 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 GAK62082.1 - 2.1e-05 24.3 0.3 4.1e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain NARP1 PF12569.8 GAK62083.1 - 3.8e-158 527.6 3.1 6.6e-158 526.8 3.1 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 GAK62083.1 - 4e-10 39.0 20.7 4.7e-06 26.3 0.1 8.3 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAK62083.1 - 1.1e-09 37.7 2.8 2.5e-05 23.9 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK62083.1 - 3.3e-08 33.9 24.8 0.16 12.5 0.0 9.3 6 2 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAK62083.1 - 6.6e-07 29.1 4.7 0.011 15.9 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAK62083.1 - 4e-06 27.2 30.0 0.68 10.9 0.0 11.4 9 2 2 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAK62083.1 - 1.9e-05 24.4 14.2 0.00016 21.5 0.1 6.0 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAK62083.1 - 6.2e-05 23.3 32.4 0.38 11.5 0.8 8.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK62083.1 - 0.00021 21.3 10.4 0.14 12.3 0.7 4.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAK62083.1 - 0.00061 20.0 23.0 0.0066 16.7 0.0 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAK62083.1 - 0.0028 18.3 34.4 1 10.1 0.0 10.0 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAK62083.1 - 0.0096 16.2 2.2 1e+02 3.6 0.1 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK62083.1 - 0.012 15.9 6.5 0.34 11.2 0.0 5.5 6 1 2 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Coilin_N PF15862.5 GAK62083.1 - 0.047 13.5 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Coilin N-terminus MerR_2 PF13591.6 GAK62083.1 - 0.056 13.3 0.2 0.51 10.2 0.1 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein FAT PF02259.23 GAK62083.1 - 0.062 12.5 0.3 0.62 9.2 0.1 2.7 3 0 0 3 3 3 0 FAT domain TPR_10 PF13374.6 GAK62083.1 - 0.15 11.9 11.5 0.17 11.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK62083.1 - 0.19 12.4 23.1 7.8 7.4 0.0 9.2 10 1 1 11 11 8 0 Tetratricopeptide repeat SSP160 PF06933.11 GAK62083.1 - 1.5 7.0 4.6 2.3 6.3 4.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ion_trans PF00520.31 GAK62084.1 - 0.0063 15.8 0.1 0.0083 15.4 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein SUR7 PF06687.12 GAK62085.1 - 6.5e-24 84.7 9.2 8.9e-24 84.3 9.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family MMPL PF03176.15 GAK62085.1 - 0.3 10.0 3.1 0.56 9.1 3.1 1.3 1 0 0 1 1 1 0 MMPL family Clc-like PF07062.12 GAK62085.1 - 5.8 6.3 6.5 12 5.3 6.5 1.5 1 0 0 1 1 1 0 Clc-like ANTH PF07651.16 GAK62086.1 - 3.7e-75 252.5 0.2 3.7e-75 252.5 0.2 2.4 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 GAK62086.1 - 8.3e-55 185.2 9.5 8.3e-55 185.2 9.5 4.9 4 1 0 4 4 4 2 I/LWEQ domain ENTH PF01417.20 GAK62086.1 - 7.6e-07 29.2 0.3 1.4e-05 25.1 0.0 3.0 2 0 0 2 2 2 1 ENTH domain TcdB_N PF12918.7 GAK62086.1 - 0.03 14.6 0.1 0.11 12.9 0.1 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain PCI PF01399.27 GAK62087.1 - 1.2e-16 61.1 0.0 4.6e-16 59.2 0.0 2.1 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 GAK62087.1 - 7.4e-14 51.6 0.9 1.8e-13 50.3 0.9 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF4228 PF14009.6 GAK62087.1 - 0.022 15.1 2.7 0.047 14.1 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Ntox34 PF15606.6 GAK62087.1 - 0.024 14.7 0.1 2.9 8.1 0.0 2.9 2 0 0 2 2 2 0 Bacterial toxin 34 DDHD PF02862.17 GAK62087.1 - 0.049 13.8 0.9 0.078 13.1 0.9 1.5 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 GAK62087.1 - 0.068 12.2 1.8 0.11 11.5 1.8 1.2 1 0 0 1 1 1 0 CLN3 protein Ndc1_Nup PF09531.10 GAK62087.1 - 0.07 11.8 3.2 0.11 11.2 3.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.11 GAK62087.1 - 0.073 11.6 11.8 0.1 11.1 11.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_Rpc4 PF05132.14 GAK62087.1 - 0.2 12.1 3.9 0.41 11.1 3.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 GAK62087.1 - 0.48 10.7 12.8 1.1 9.5 12.8 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Serinc PF03348.15 GAK62087.1 - 0.58 9.0 1.5 0.86 8.5 1.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 GAK62087.1 - 1.1 9.0 13.2 2.3 8.0 13.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 GAK62087.1 - 2.3 8.2 4.4 4.9 7.1 4.4 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 GAK62087.1 - 3.3 6.4 7.7 5.2 5.7 7.7 1.2 1 0 0 1 1 1 0 Presenilin eIF3_subunit PF08597.10 GAK62087.1 - 4.7 7.0 24.4 0.56 10.1 18.4 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Connexin PF00029.19 GAK62087.1 - 5.6 6.7 6.7 10 5.8 6.7 1.4 1 0 0 1 1 1 0 Connexin Pkinase PF00069.25 GAK62088.1 - 2.2e-27 96.1 0.0 2.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62088.1 - 5.2e-16 58.7 0.0 6.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK62088.1 - 1.1e-09 37.6 0.1 1.7e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAK62088.1 - 0.00023 21.2 0.2 0.0081 16.1 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAK62088.1 - 0.039 12.9 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 GAK62088.1 - 0.067 12.5 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_6 PF08030.12 GAK62089.1 - 0.00077 19.6 0.1 0.0016 18.6 0.1 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 GAK62089.1 - 0.0013 19.3 0.0 0.0042 17.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Drc1-Sld2 PF11719.8 GAK62090.1 - 1.3e-08 34.9 15.4 1.3e-08 34.9 15.4 2.5 2 1 0 2 2 2 1 DNA replication and checkpoint protein MAP65_ASE1 PF03999.12 GAK62090.1 - 6.6 5.3 14.0 12 4.4 14.0 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_L30 PF00327.20 GAK62092.1 - 2.4e-11 43.3 0.0 3.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e BBS2_C PF14782.6 GAK62092.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal zf-RING_5 PF14634.6 GAK62093.1 - 0.0023 17.9 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK62093.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.0 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 GAK62093.1 - 0.15 12.4 0.2 0.15 12.4 0.2 1.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 GAK62093.1 - 0.24 11.2 0.6 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 RING-like zinc finger RabGAP-TBC PF00566.18 GAK62094.1 - 4.9e-36 124.4 0.0 6.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 GAK62095.1 - 5.5e-62 209.5 0.0 1.1e-61 208.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62095.1 - 1.7e-24 86.5 0.0 2.6e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK62095.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAK62095.1 - 0.017 15.1 0.1 0.054 13.4 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAK62095.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 GAK62095.1 - 0.11 12.0 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAK62095.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tannase PF07519.11 GAK62096.1 - 1.7e-79 267.9 2.0 1.8e-78 264.6 2.0 2.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 GAK62096.1 - 1.9e-05 24.0 0.0 0.0028 16.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAK62096.1 - 0.0051 16.3 0.0 0.99 8.8 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Glyco_hydro_38N PF01074.22 GAK62097.1 - 1.2e-78 264.4 1.4 1.8e-78 263.8 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAK62097.1 - 2.3e-43 148.8 0.0 3.8e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAK62097.1 - 4.1e-28 97.4 0.0 1e-27 96.1 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAK62097.1 - 5.6e-10 39.2 0.1 2.1e-09 37.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Con-6 PF10346.9 GAK62097.1 - 2.4e-07 30.7 0.1 4.3e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Glyco_hydro_57 PF03065.15 GAK62097.1 - 0.002 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 RCC1 PF00415.18 GAK62098.1 - 2e-42 143.5 5.2 1.7e-06 28.5 0.1 7.9 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAK62098.1 - 1.8e-28 97.7 20.3 1.4e-07 31.1 0.1 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat NAD_Gly3P_dh_N PF01210.23 GAK62099.1 - 1.2e-47 161.7 0.1 2.5e-47 160.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 GAK62099.1 - 2.4e-47 160.8 0.0 4.1e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 GAK62099.1 - 0.004 17.7 0.4 0.049 14.2 0.4 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sec2p PF06428.11 GAK62101.1 - 2.7e-18 65.7 9.3 2.7e-18 65.7 9.3 2.7 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4763 PF15960.5 GAK62101.1 - 0.0068 15.7 0.2 0.0068 15.7 0.2 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) DUF948 PF06103.11 GAK62101.1 - 0.085 13.1 6.0 4.3 7.7 1.2 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF713 PF05218.14 GAK62101.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF713) AroM PF07302.11 GAK62101.1 - 0.31 10.4 4.7 0.44 9.9 0.1 2.7 3 0 0 3 3 3 0 AroM protein Bacillus_HBL PF05791.11 GAK62101.1 - 1.9 8.3 10.3 3.9 7.3 2.2 2.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) KxDL PF10241.9 GAK62101.1 - 2.2 8.6 5.1 10 6.5 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Med9 PF07544.13 GAK62101.1 - 3.3 7.9 9.7 0.12 12.5 1.0 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 GAK62101.1 - 3.6 6.6 13.4 0.6 9.1 8.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TRAF_BIRC3_bd PF16673.5 GAK62101.1 - 3.9 7.3 7.6 0.36 10.6 0.7 2.8 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Baculo_PEP_C PF04513.12 GAK62101.1 - 7.3 6.6 7.4 3.7 7.6 1.8 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 GAK62101.1 - 8.3 6.6 13.2 0.15 12.2 1.9 3.3 3 1 1 4 4 4 0 TolA binding protein trimerisation PH_9 PF15410.6 GAK62102.1 - 6.5e-30 103.9 0.0 1.5e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 GAK62102.1 - 1.9e-27 96.1 0.0 4.2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 GAK62102.1 - 0.0009 19.7 0.0 0.0052 17.3 0.0 2.2 1 1 0 1 1 1 1 PH domain Rrp40_N PF18311.1 GAK62102.1 - 0.19 11.7 4.5 3.6 7.6 0.5 3.1 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain Lzipper-MIP1 PF14389.6 GAK62102.1 - 0.34 11.2 5.0 29 5.0 3.1 2.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 zf-C2H2 PF00096.26 GAK62103.1 - 1e-08 35.2 14.6 0.00034 20.9 1.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK62103.1 - 0.006 17.3 11.9 0.25 12.3 3.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK62103.1 - 0.012 16.1 7.6 0.34 11.4 1.7 3.8 3 0 0 3 3 3 0 Zinc-finger double domain DUF3268 PF11672.8 GAK62103.1 - 0.052 13.9 0.3 0.088 13.1 0.3 1.3 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2HC_2 PF13913.6 GAK62103.1 - 2.5 8.1 7.3 3.3 7.7 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 GAK62103.1 - 7.6 6.4 12.0 1.9 8.3 0.2 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type NAD_kinase PF01513.21 GAK62105.1 - 1.1e-73 248.0 0.0 3.1e-73 246.5 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase GDA1_CD39 PF01150.17 GAK62106.1 - 9.3e-90 301.3 0.0 1.3e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 GAK62106.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family P5CR_dimer PF14748.6 GAK62107.1 - 1.7e-37 127.8 3.3 1.7e-37 127.8 3.3 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAK62107.1 - 2e-13 50.8 0.5 1.6e-11 44.7 0.5 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.29 GAK62108.1 - 1.6e-44 151.6 0.1 4.5e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAK62108.1 - 1.3e-08 34.7 0.2 8e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 GAK62108.1 - 2.2e-08 34.2 0.7 6.4e-08 32.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAK62108.1 - 3.1e-08 34.2 0.2 3.1e-05 24.4 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 GAK62108.1 - 7.6e-08 32.7 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 GAK62108.1 - 4.4e-06 26.4 0.1 2e-05 24.3 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain DUF815 PF05673.13 GAK62108.1 - 4.9e-06 25.9 0.1 1.9e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAK62108.1 - 0.00017 22.1 0.0 0.0028 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAK62108.1 - 0.00019 21.7 3.2 0.01 16.1 0.1 3.0 3 1 1 4 4 2 1 AAA domain NTPase_1 PF03266.15 GAK62108.1 - 0.00024 21.0 0.2 0.0038 17.2 0.0 2.6 3 0 0 3 3 3 1 NTPase RuvB_N PF05496.12 GAK62108.1 - 0.00027 20.7 0.0 0.00077 19.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 GAK62108.1 - 0.00032 20.5 0.1 0.00097 18.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAK62108.1 - 0.00053 20.3 0.4 0.0019 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAK62108.1 - 0.0014 17.9 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 GAK62108.1 - 0.0014 18.7 0.0 0.0046 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAK62108.1 - 0.0019 18.2 0.0 0.005 16.8 0.0 1.6 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAK62108.1 - 0.0022 18.4 0.0 0.0079 16.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase TniB PF05621.11 GAK62108.1 - 0.0022 17.4 0.6 0.65 9.4 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 GAK62108.1 - 0.0027 17.3 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 GAK62108.1 - 0.005 17.0 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAK62108.1 - 0.007 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAK62108.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAK62108.1 - 0.0084 16.0 0.1 0.072 13.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 GAK62108.1 - 0.011 15.4 0.1 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 GAK62108.1 - 0.014 15.2 0.1 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAK62108.1 - 0.024 14.4 0.2 0.049 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAK62108.1 - 0.024 14.5 1.1 0.38 10.6 0.0 2.9 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 GAK62108.1 - 0.042 13.7 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 GAK62108.1 - 0.049 12.5 0.2 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase HTH_Tnp_1_2 PF13022.6 GAK62108.1 - 0.06 13.5 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Parvo_NS1 PF01057.17 GAK62108.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 GAK62108.1 - 0.082 12.6 0.2 1.4 8.6 0.0 2.8 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 GAK62108.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAK62108.1 - 0.12 12.9 2.3 0.76 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAK62108.1 - 0.12 11.7 0.0 0.62 9.4 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 GAK62108.1 - 0.25 11.7 1.3 0.4 11.0 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 GAK62108.1 - 0.41 10.2 3.8 0.2 11.2 0.5 2.1 2 1 0 2 2 2 0 AAA domain DUF2076 PF09849.9 GAK62109.1 - 2e-08 34.6 13.5 2.6e-08 34.2 13.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 GAK62109.1 - 0.0004 20.4 5.8 0.0006 19.9 5.8 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 GAK62109.1 - 0.019 15.0 3.1 0.031 14.3 3.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TFIIA PF03153.13 GAK62109.1 - 1.8 8.5 9.4 2.1 8.3 9.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SET PF00856.28 GAK62112.1 - 2e-09 38.1 1.3 2.8e-08 34.3 0.0 3.2 2 2 0 2 2 2 1 SET domain zf-rbx1 PF12678.7 GAK62113.1 - 2.1e-13 50.3 3.2 3.6e-13 49.6 3.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAK62113.1 - 2.5e-09 37.3 6.6 6.6e-09 36.0 6.6 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAK62113.1 - 1.9e-06 27.6 2.9 3.5e-06 26.8 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK62113.1 - 2e-06 27.7 1.0 3.9e-06 26.8 1.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAK62113.1 - 3.4e-06 26.8 3.3 8e-06 25.6 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAK62113.1 - 5.1e-06 26.5 0.2 9.8e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAK62113.1 - 0.00012 21.9 2.6 0.0015 18.3 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAK62113.1 - 0.00016 21.2 0.8 0.00032 20.2 0.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAK62113.1 - 0.0003 20.7 4.4 0.00093 19.1 4.6 1.7 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAK62113.1 - 0.00092 19.0 4.0 0.0023 17.8 4.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAK62113.1 - 0.0035 17.5 2.2 0.0057 16.8 1.4 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 GAK62113.1 - 0.004 17.3 0.5 0.0079 16.4 0.5 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 GAK62113.1 - 0.0061 16.3 0.4 0.0061 16.3 0.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING-like PF08746.11 GAK62113.1 - 0.094 13.0 1.7 0.18 12.2 1.7 1.4 1 0 0 1 1 1 0 RING-like domain DLIC PF05783.11 GAK62113.1 - 7.5 5.3 7.5 9.3 4.9 0.2 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Rpr2 PF04032.16 GAK62114.1 - 0.22 11.9 3.7 0.11 12.8 0.8 2.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TPR_MLP1_2 PF07926.12 GAK62115.1 - 0.0045 17.0 48.6 0.26 11.3 16.9 3.6 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein DUF3597 PF12200.8 GAK62115.1 - 0.12 12.9 0.2 0.12 12.9 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3597) CENP-F_leu_zip PF10473.9 GAK62115.1 - 0.15 12.1 49.6 0.7 9.9 12.6 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dam1 PF08653.10 GAK62115.1 - 0.18 11.6 0.2 1.1 9.2 0.2 2.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF4201 PF13870.6 GAK62115.1 - 0.74 9.5 40.2 0.62 9.8 15.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 GAK62115.1 - 0.89 8.4 43.2 0.28 10.0 23.2 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 GAK62115.1 - 1.6 8.2 39.7 0.37 10.3 24.3 3.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4763 PF15960.5 GAK62115.1 - 1.6 7.9 37.7 0.05 12.9 21.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) Sec7_N PF12783.7 GAK62116.1 - 2.7e-44 150.8 2.5 2.7e-44 150.8 2.5 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 GAK62116.1 - 4.9e-37 127.3 1.1 1.2e-36 126.1 1.1 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 GAK62116.1 - 3.8e-21 75.0 2.6 8.9e-14 50.6 1.8 4.0 3 1 1 4 4 4 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 GAK62116.1 - 0.00098 18.9 1.3 0.019 14.8 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) PHTB1_C PF14728.6 GAK62116.1 - 1.4 7.9 5.2 0.95 8.5 0.1 2.8 3 0 0 3 3 3 0 PTHB1 C-terminus Mito_carr PF00153.27 GAK62118.1 - 1.4e-16 60.1 6.4 9.4e-06 25.5 0.0 5.4 4 1 1 5 5 5 5 Mitochondrial carrier protein HrpJ PF07201.11 GAK62118.1 - 0.18 12.1 2.6 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 HrpJ-like domain PhoR PF11808.8 GAK62119.1 - 0.75 10.2 3.0 1.5 9.2 3.0 1.5 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Cupin_5 PF06172.11 GAK62121.1 - 7.3e-32 110.5 0.1 1.4e-17 64.2 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) NYN PF01936.18 GAK62122.1 - 2.1e-26 93.2 0.0 4.1e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 NYN domain MGC-24 PF05283.11 GAK62123.1 - 0.098 13.1 6.5 0.031 14.7 3.0 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Phage_holin_3_6 PF07332.11 GAK62123.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1218 PF06749.12 GAK62124.1 - 0.0084 16.6 0.1 0.14 12.7 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) SPOR PF05036.13 GAK62124.1 - 0.13 12.6 0.3 0.13 12.6 0.3 2.0 2 0 0 2 2 2 0 Sporulation related domain EBP50_C PF09007.11 GAK62124.1 - 7 7.7 11.4 0.54 11.2 4.8 2.3 1 1 0 2 2 2 0 EBP50, C-terminal WD40 PF00400.32 GAK62125.1 - 6.2e-19 68.0 6.9 5.8e-05 23.8 0.4 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK62125.1 - 8.9e-07 29.1 0.0 2.2 8.6 0.0 5.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAK62125.1 - 0.02 13.4 0.0 0.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Lgl_C PF08596.10 GAK62125.1 - 0.11 11.2 0.3 0.19 10.4 0.3 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal CUE PF02845.16 GAK62126.1 - 1.3e-12 47.2 0.0 2.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain Fungal_trans PF04082.18 GAK62127.1 - 3.1e-26 92.0 0.0 5.2e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62127.1 - 1.1e-09 38.3 6.2 1.1e-09 38.3 6.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NYD-SP28_assoc PF14775.6 GAK62127.1 - 0.32 11.1 1.4 0.99 9.6 0.7 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Sugar_tr PF00083.24 GAK62128.1 - 5.3e-31 108.0 22.6 5.9e-22 78.1 11.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAK62128.1 - 1.3e-25 90.1 47.9 7.7e-24 84.3 30.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nucleoside_tran PF01733.18 GAK62128.1 - 0.00013 21.5 0.0 0.00041 19.8 0.0 1.8 2 0 0 2 2 2 1 Nucleoside transporter AsnC_trans_reg2 PF17805.1 GAK62129.1 - 0.024 14.8 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 AsnC-like ligand binding domain Zn_clus PF00172.18 GAK62130.1 - 3.3e-06 27.1 9.5 3.3e-06 27.1 9.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK62130.1 - 0.0075 15.3 0.2 0.047 12.7 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_delta_4 PF04081.13 GAK62132.1 - 3.9e-24 85.4 0.2 4.9e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 ATP_bind_1 PF03029.17 GAK62133.1 - 3.5e-66 223.4 0.0 5e-55 186.9 0.0 2.8 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 GAK62133.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.26 GAK62134.1 - 2.2e-43 147.3 0.0 2.8e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 GAK62134.1 - 7.1e-23 80.2 0.8 1.3e-22 79.4 0.8 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 GAK62134.1 - 4.9e-05 23.2 0.1 8.6e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain Prok-E2_B PF14461.6 GAK62134.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B ArfGap PF01412.18 GAK62135.1 - 1.6e-32 112.0 0.1 1.6e-32 112.0 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-tcix PF14952.6 GAK62135.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding NOT2_3_5 PF04153.18 GAK62136.1 - 5.5e-34 117.1 1.9 5.5e-34 117.1 1.9 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Joubert PF15392.6 GAK62136.1 - 0.68 9.6 7.3 1.1 8.8 7.3 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated TFIIA PF03153.13 GAK62136.1 - 9.5 6.1 20.0 0.15 12.0 10.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_3 PF13920.6 GAK62139.1 - 5.5e-09 35.8 5.1 2.6e-07 30.4 1.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK62139.1 - 6.7e-08 32.2 4.6 2.5e-07 30.4 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK62139.1 - 1.7e-07 31.0 0.7 1.7e-07 31.0 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK62139.1 - 4.8e-07 29.7 1.8 4.8e-07 29.7 1.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAK62139.1 - 3.5e-06 27.2 6.4 5.1e-06 26.7 1.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAK62139.1 - 3e-05 23.9 1.4 3e-05 23.9 1.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAK62139.1 - 3.7e-05 23.5 5.5 0.00043 20.1 1.8 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAK62139.1 - 0.008 16.3 2.7 0.008 16.3 2.7 2.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAK62139.1 - 6.5 7.1 5.8 8.9 6.7 2.3 2.6 2 1 1 3 3 3 0 RING-H2 zinc finger domain EF-hand_1 PF00036.32 GAK62140.1 - 5.6e-27 91.2 8.6 2.7e-08 32.8 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 GAK62140.1 - 8.3e-27 93.4 6.9 1e-17 64.3 0.8 3.1 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GAK62140.1 - 5.3e-23 78.9 4.5 1.5e-06 27.7 0.1 5.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 GAK62140.1 - 2.2e-14 52.2 7.1 0.00017 20.9 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 GAK62140.1 - 9.4e-14 51.0 6.2 0.00095 19.0 0.1 4.4 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 GAK62140.1 - 9.6e-11 41.6 2.3 0.0035 17.3 0.0 4.0 2 1 2 4 4 4 4 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAK62140.1 - 6e-05 23.3 1.4 0.041 14.2 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAK62140.1 - 0.00041 20.6 2.6 0.78 10.1 0.1 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 GAK62140.1 - 0.034 14.6 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand DUF1679 PF07914.11 GAK62140.1 - 0.068 12.0 0.6 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.11 GAK62140.1 - 0.14 12.4 0.0 3.9 7.6 0.0 2.6 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 GAK62140.1 - 0.16 11.9 2.9 20 5.0 0.0 3.3 2 1 0 3 3 3 0 Caleosin related protein ETF PF01012.21 GAK62141.1 - 4.1e-44 150.6 0.2 5.5e-44 150.2 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Glycos_transf_3 PF00591.21 GAK62142.1 - 2e-74 250.4 0.0 2.4e-69 233.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain TarH PF02203.15 GAK62142.1 - 0.087 12.7 0.7 0.15 11.9 0.7 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Peptidase_S8 PF00082.22 GAK62143.1 - 7.4e-56 189.6 0.0 1.4e-34 119.8 0.0 2.5 2 1 1 3 3 3 2 Subtilase family TPPII PF12580.8 GAK62143.1 - 5.7e-52 176.0 0.5 5.7e-52 176.0 0.5 1.8 2 0 0 2 2 2 1 Tripeptidyl peptidase II Thioredoxin_13 PF18401.1 GAK62143.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain RRM_1 PF00076.22 GAK62144.1 - 4e-57 189.9 0.2 2.5e-17 62.4 0.0 6.9 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK62144.1 - 3.2e-05 24.0 0.0 0.87 9.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 GAK62144.1 - 0.0026 17.6 0.1 1.3 8.8 0.0 3.5 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain START PF01852.19 GAK62145.1 - 1.9e-06 27.4 0.0 5.1e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 START domain MSP1a PF11670.8 GAK62145.1 - 0.027 13.8 3.1 0.041 13.2 3.1 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Nucleoside_tran PF01733.18 GAK62146.1 - 4.1e-31 108.5 4.8 4.4e-31 108.4 1.5 2.5 2 1 0 2 2 2 1 Nucleoside transporter Phage_holin_2_4 PF16082.5 GAK62146.1 - 0.065 13.0 0.4 0.18 11.5 0.4 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like BRO1 PF03097.18 GAK62147.1 - 1.5e-113 379.6 0.8 1.5e-113 379.6 0.8 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAK62147.1 - 3.7e-56 190.6 8.8 5.8e-56 190.0 8.8 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Med6 PF04934.14 GAK62149.1 - 2.9e-44 150.1 0.0 3.9e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component ATP-synt_C PF00137.21 GAK62150.1 - 5.7e-34 116.3 35.0 7.6e-22 77.4 15.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C YiaAB PF05360.14 GAK62151.1 - 0.61 10.4 5.9 0.35 11.1 0.9 2.8 2 0 0 2 2 2 0 yiaA/B two helix domain AAA PF00004.29 GAK62152.1 - 1.3e-39 135.7 0.0 2.1e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK62152.1 - 1.1e-11 44.3 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAK62152.1 - 6.3e-07 29.3 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAK62152.1 - 3e-06 27.7 0.3 0.00018 22.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAK62152.1 - 8.9e-06 25.8 0.2 5.9e-05 23.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAK62152.1 - 4.8e-05 23.7 0.2 0.0021 18.3 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 GAK62152.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAK62152.1 - 0.00019 21.6 0.0 0.00034 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAK62152.1 - 0.00019 21.6 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAK62152.1 - 0.00031 21.3 0.0 0.00066 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAK62152.1 - 0.00064 19.2 0.3 0.0023 17.4 0.2 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 GAK62152.1 - 0.00079 18.9 0.1 1.6 8.1 0.0 2.6 2 1 1 3 3 3 2 Bacterial TniB protein IstB_IS21 PF01695.17 GAK62152.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 GAK62152.1 - 0.002 17.4 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 GAK62152.1 - 0.0021 17.8 0.1 0.0041 16.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAK62152.1 - 0.0029 18.0 0.0 0.0074 16.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 GAK62152.1 - 0.0032 17.0 0.1 0.03 13.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAK62152.1 - 0.0036 17.1 0.3 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 GAK62152.1 - 0.0036 17.5 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 GAK62152.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 GAK62152.1 - 0.0066 16.0 0.1 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAK62152.1 - 0.0098 15.6 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 GAK62152.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 GAK62152.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 Bacterial dnaA protein TsaE PF02367.17 GAK62152.1 - 0.018 15.1 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 GAK62152.1 - 0.019 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 GAK62152.1 - 0.02 14.6 0.0 0.07 12.8 0.0 1.9 3 0 0 3 3 2 0 Guanylate kinase Rad17 PF03215.15 GAK62152.1 - 0.021 14.8 0.1 0.13 12.1 0.0 2.2 2 1 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 GAK62152.1 - 0.022 14.1 0.0 0.28 10.5 0.0 2.1 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 GAK62152.1 - 0.032 14.2 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 GAK62152.1 - 0.033 14.6 0.1 0.073 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAK62152.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IPT PF01745.16 GAK62152.1 - 0.08 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase CPT PF07931.12 GAK62152.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 GAK62152.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Hydin_ADK PF17213.3 GAK62152.1 - 0.13 12.5 0.4 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 GAK62152.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 GAK62152.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_6 PF12774.7 GAK62152.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 GAK62152.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Proteasome PF00227.26 GAK62153.1 - 7.2e-41 139.8 0.0 8.3e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ETC_C1_NDUFA4 PF04800.12 GAK62154.1 - 1.4e-36 124.6 0.1 2.1e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region RPAP1_C PF08620.10 GAK62155.1 - 3.4e-24 84.7 0.3 7.8e-24 83.6 0.3 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 GAK62155.1 - 1.3e-07 31.3 0.5 2.9e-07 30.1 0.5 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.22 GAK62155.1 - 0.009 16.2 0.7 6.5 7.3 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat TFIID-18kDa PF02269.16 GAK62156.1 - 9e-14 51.3 0.2 7.3e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit FHA PF00498.26 GAK62157.1 - 3.7e-09 36.8 0.0 1.1e-08 35.3 0.0 1.8 1 1 0 1 1 1 1 FHA domain zf-C2H2_10 PF16588.5 GAK62158.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.4 1 1 1 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 GAK62159.1 - 0.099 12.8 0.5 0.099 12.8 0.5 2.0 3 0 0 3 3 3 0 Zinc knuckle Cupin_8 PF13621.6 GAK62161.1 - 4e-60 203.7 0.0 5.1e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain CRAL_TRIO PF00650.20 GAK62162.1 - 7.1e-33 113.6 0.0 1.2e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAK62162.1 - 6.5e-10 39.0 0.7 1.9e-09 37.5 0.7 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAK62162.1 - 9e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain cobW PF02492.19 GAK62163.1 - 3.4e-50 170.1 4.5 2.6e-37 128.1 0.6 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.23 GAK62163.1 - 2.8e-24 85.7 0.3 1.3e-23 83.6 0.1 2.3 2 0 0 2 2 2 1 HIT domain CobW_C PF07683.14 GAK62163.1 - 3.1e-18 65.5 0.8 1.3e-13 50.6 0.1 2.8 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.8 GAK62163.1 - 0.00022 21.7 0.5 0.0006 20.3 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding MeaB PF03308.16 GAK62163.1 - 0.00022 20.3 0.6 0.064 12.2 0.1 2.7 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAK62163.1 - 0.00095 19.6 0.4 0.046 14.1 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAK62163.1 - 0.0016 18.4 0.1 2.8 7.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase CwfJ_C_1 PF04677.15 GAK62163.1 - 0.0022 17.9 0.0 0.006 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MobB PF03205.14 GAK62163.1 - 0.0038 17.1 0.0 0.0086 16.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 GAK62163.1 - 0.0069 16.4 0.1 0.029 14.4 0.0 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE BUD22 PF09073.10 GAK62163.1 - 0.0083 15.5 0.3 0.0083 15.5 0.3 1.9 2 0 0 2 2 2 1 BUD22 GTP_EFTU PF00009.27 GAK62163.1 - 0.013 15.0 0.1 4.9 6.6 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 GAK62163.1 - 0.13 12.4 0.3 1.1 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain CsbD PF05532.12 GAK62164.1 - 9e-21 73.5 20.3 1.6e-11 43.9 7.6 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 GAK62164.1 - 0.00018 21.8 0.9 0.00028 21.2 0.4 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF202 PF02656.15 GAK62165.1 - 2.1e-20 72.9 0.3 2.1e-20 72.9 0.3 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF202) SH3_2 PF07653.17 GAK62166.1 - 7.2e-06 25.6 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAK62166.1 - 9.7e-06 25.4 0.5 2.3e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 GAK62166.1 - 0.0042 16.6 0.1 0.11 12.1 0.1 2.6 1 1 0 1 1 1 1 SH3 domain Zn_clus PF00172.18 GAK62167.1 - 2.7e-06 27.4 12.0 6e-06 26.3 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob1_phocein PF03637.17 GAK62169.1 - 8.9e-21 74.6 0.0 8.9e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Mob1/phocein family DUF3246 PF11596.8 GAK62169.1 - 3.5 7.0 13.6 0.86 9.0 9.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Vfa1 PF08432.10 GAK62169.1 - 3.8 7.8 8.7 0.91 9.8 0.2 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TFIIB PF00382.19 GAK62171.1 - 3.4e-31 107.1 3.6 1.1e-16 60.6 0.0 3.7 3 1 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GAK62171.1 - 7.5e-30 103.3 3.3 7.5e-30 103.3 3.3 3.7 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 GAK62171.1 - 6.2e-10 38.4 0.6 1.4e-09 37.3 0.6 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 GAK62171.1 - 0.00035 20.3 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain PX PF00787.24 GAK62172.1 - 5.8e-16 58.5 0.1 1.9e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 PX domain Homeobox_KN PF05920.11 GAK62173.1 - 1.2e-18 66.7 0.0 2.3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAK62173.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain ATG16 PF08614.11 GAK62174.1 - 0.0031 17.8 3.8 0.0031 17.8 3.8 5.9 4 2 1 5 5 5 1 Autophagy protein 16 (ATG16) DUF1970 PF09301.10 GAK62174.1 - 0.1 12.8 1.9 0.56 10.5 1.9 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) GNAT_acetyltr_2 PF13718.6 GAK62174.1 - 0.13 11.6 3.3 2.4 7.5 0.0 2.7 2 0 0 2 2 2 0 GNAT acetyltransferase 2 PGM_PMM_I PF02878.16 GAK62175.1 - 3e-37 127.4 0.2 4.4e-37 126.9 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAK62175.1 - 3.8e-27 94.7 0.0 6.3e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAK62175.1 - 2.2e-16 60.3 0.0 4.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAK62175.1 - 3.7e-06 27.0 0.0 8.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain tRNA_int_endo PF01974.17 GAK62176.1 - 2.6e-11 43.4 0.0 5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pkinase PF00069.25 GAK62177.1 - 3.8e-71 239.5 0.0 4.9e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62177.1 - 1.5e-31 109.6 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAK62177.1 - 3.3e-15 56.5 1.8 3.3e-15 56.5 1.8 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAK62177.1 - 4.4e-06 25.9 0.0 6.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAK62177.1 - 0.0096 15.3 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAK62177.1 - 0.036 13.7 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 bZIP_1 PF00170.21 GAK62178.1 - 0.00031 20.8 2.8 0.00059 19.9 2.0 1.8 2 0 0 2 2 2 1 bZIP transcription factor HeH PF12949.7 GAK62178.1 - 0.005 16.5 0.5 0.0096 15.6 0.5 1.5 1 0 0 1 1 1 1 HeH/LEM domain bZIP_2 PF07716.15 GAK62178.1 - 0.04 14.0 2.2 0.04 14.0 2.2 2.3 3 0 0 3 3 3 0 Basic region leucine zipper Rad60-SLD PF11976.8 GAK62179.1 - 7.2e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Draxin PF15550.6 GAK62179.1 - 2.2 8.1 9.0 0.34 10.7 4.6 1.8 2 0 0 2 2 2 0 Draxin Peptidase_S24 PF00717.23 GAK62180.1 - 4.1e-09 36.3 0.1 3.1e-08 33.5 0.2 2.0 1 1 1 2 2 2 1 Peptidase S24-like Vma12 PF11712.8 GAK62180.1 - 0.13 12.3 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Med16 PF11635.8 GAK62183.1 - 10 3.9 5.5 1.3 6.8 0.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 16 F-box-like PF12937.7 GAK62184.1 - 0.0015 18.4 1.1 0.0084 16.0 0.1 2.8 3 1 0 3 3 3 1 F-box-like zf-CCHC_6 PF15288.6 GAK62184.1 - 0.23 11.3 2.6 0.69 9.8 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle BASP1 PF05466.12 GAK62184.1 - 6.3 6.7 5.1 9 6.2 5.1 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) MFS_1 PF07690.16 GAK62185.1 - 1.1e-31 110.0 46.7 1.1e-31 110.0 46.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK62185.1 - 1.8e-08 33.7 32.4 2.6e-05 23.3 11.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3382 PF11862.8 GAK62185.1 - 0.57 10.5 11.6 0.49 10.7 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Abhydrolase_1 PF00561.20 GAK62186.1 - 2.6e-19 69.9 0.3 1.5e-16 60.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK62186.1 - 8e-18 65.9 10.8 1.2e-17 65.3 10.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK62186.1 - 6.4e-14 51.8 0.0 1.4e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 GAK62186.1 - 0.0029 16.5 0.0 0.004 16.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.7 GAK62186.1 - 0.012 15.4 0.0 0.08 12.7 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 GAK62186.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) ATP-synt_Z PF16594.5 GAK62186.1 - 1.2 8.6 4.4 0.33 10.5 0.5 2.0 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated ANAPC4_WD40 PF12894.7 GAK62187.1 - 0.00051 20.3 0.0 20 5.5 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Chitin_synth_1 PF01644.17 GAK62188.1 - 8.3e-79 263.2 0.1 1.4e-78 262.5 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAK62188.1 - 4.5e-30 103.4 0.1 9.4e-30 102.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAK62188.1 - 6e-21 74.6 2.2 5.1e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAK62188.1 - 0.01 15.8 12.1 0.077 12.9 12.1 2.4 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK62188.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 LRR19-TM PF15176.6 GAK62188.1 - 3.2 7.8 5.2 0.49 10.4 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Zn_clus PF00172.18 GAK62189.1 - 1.3e-09 38.0 8.1 2.6e-09 37.0 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_V PF00488.21 GAK62190.1 - 8.9e-37 126.9 0.0 1.6e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAK62190.1 - 2.4e-11 44.2 0.4 4.7e-11 43.3 0.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAK62190.1 - 0.0065 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV NB-ARC PF00931.22 GAK62190.1 - 0.01 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 GAK62190.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAK62190.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 GAK62190.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 GAK62191.1 - 1.8e-64 217.6 0.0 3.1e-64 216.9 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62191.1 - 7.5e-40 136.8 0.0 9.7e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK62191.1 - 2.6e-07 30.3 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GAK62191.1 - 0.049 13.2 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAK62191.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NFACT-R_1 PF05670.13 GAK62192.1 - 1.9e-39 134.7 0.1 4.1e-39 133.6 0.0 1.6 2 0 0 2 2 2 1 NFACT protein RNA binding domain CDC45 PF02724.14 GAK62192.1 - 1.2 7.4 12.1 1.4 7.1 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GAK62192.1 - 1.7 6.7 6.4 2 6.4 6.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Histone PF00125.24 GAK62193.1 - 1.3e-16 61.1 0.2 3.8e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 GAK62193.1 - 2.1e-12 46.5 0.2 4e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 GAK62193.1 - 0.067 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Formyl_trans_N PF00551.19 GAK62194.1 - 3.4e-30 105.1 0.0 3.2e-18 66.1 0.1 2.7 2 0 0 2 2 2 2 Formyl transferase Gelsolin PF00626.22 GAK62194.1 - 0.021 14.7 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 Gelsolin repeat Zn_clus PF00172.18 GAK62195.1 - 9.7e-08 32.0 6.0 1.6e-07 31.3 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4203 PF13886.6 GAK62197.1 - 6.3e-05 22.7 24.3 6.3e-05 22.7 24.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4203) Sigma70_ECF PF07638.11 GAK62197.1 - 0.2 11.6 0.4 0.36 10.7 0.4 1.3 1 0 0 1 1 1 0 ECF sigma factor Arrestin_N PF00339.29 GAK62198.1 - 0.00025 21.1 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain zf-CCHC PF00098.23 GAK62199.1 - 0.0097 16.0 3.0 0.0097 16.0 3.0 4.9 4 0 0 4 4 4 4 Zinc knuckle Chitin_synth_1 PF01644.17 GAK62200.1 - 2.5e-79 264.9 0.0 3.6e-79 264.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAK62200.1 - 6.8e-30 102.8 0.1 1.5e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAK62200.1 - 1.2e-25 90.1 7.9 2.3e-20 72.7 0.1 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAK62200.1 - 4.6e-06 26.7 2.6 4.6e-06 26.7 2.6 2.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Pil1 PF13805.6 GAK62201.1 - 2.2e-69 233.9 2.1 3.9e-69 233.1 2.1 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 PDT PF00800.18 GAK62201.1 - 1.1e-64 217.6 1.2 2.5e-64 216.5 0.0 2.2 3 0 0 3 3 3 1 Prephenate dehydratase DUF2408 PF10303.9 GAK62201.1 - 0.13 12.9 1.2 0.3 11.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ARGLU PF15346.6 GAK62201.1 - 1.4 8.8 18.1 0.98 9.3 8.5 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 RNase_PH PF01138.21 GAK62202.1 - 4.1e-25 88.8 0.0 8.3e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAK62202.1 - 0.0084 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cnd3 PF12719.7 GAK62203.1 - 5.2e-82 275.3 5.9 8.9e-82 274.6 0.4 2.7 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAK62203.1 - 3.2e-12 46.6 6.6 1e-06 29.0 0.5 4.3 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 GAK62203.1 - 2.4e-09 37.5 5.9 0.066 13.7 0.0 5.9 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 GAK62203.1 - 7.4e-08 32.0 11.1 1.1 9.7 0.0 6.6 5 0 0 5 5 5 4 HEAT repeat Cnd1 PF12717.7 GAK62203.1 - 3.2e-05 24.0 6.2 0.017 15.2 0.4 4.0 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAK62203.1 - 0.00016 20.4 0.1 0.17 10.4 0.0 2.6 2 1 0 2 2 2 2 Adaptin N terminal region DUF4611 PF15387.6 GAK62203.1 - 0.0027 17.9 19.7 3.4 7.9 0.5 4.7 4 0 0 4 4 4 2 Domain of unknown function (DUF4611) RTP1_C1 PF10363.9 GAK62203.1 - 0.046 13.9 4.4 9.5 6.4 0.1 4.3 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Methyltrans_Mon PF14314.6 GAK62203.1 - 0.096 10.7 0.1 0.25 9.3 0.1 1.6 1 1 0 1 1 1 0 Virus-capping methyltransferase Sigma70_ner PF04546.13 GAK62203.1 - 3.4 7.5 14.0 5.6 6.8 0.0 3.8 3 1 1 4 4 4 0 Sigma-70, non-essential region Myc_N PF01056.18 GAK62203.1 - 7.5 6.3 15.0 2.2 8.1 5.2 3.2 3 0 0 3 3 3 0 Myc amino-terminal region Sporozoite_P67 PF05642.11 GAK62203.1 - 9.9 4.1 6.6 11 3.9 0.0 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NAD_binding_7 PF13241.6 GAK62204.1 - 1.3e-28 99.5 0.0 2.3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 GAK62204.1 - 3.4e-26 90.7 0.4 5.2e-26 90.1 0.4 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 GAK62204.1 - 3.7e-11 42.3 0.4 8.3e-11 41.1 0.4 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 GAK62204.1 - 0.24 10.7 2.8 0.3 10.4 0.0 2.3 3 0 0 3 3 3 0 ThiF family TPR_1 PF00515.28 GAK62205.1 - 1.1e-22 78.9 10.9 0.0034 17.1 0.2 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAK62205.1 - 1.2e-21 75.0 24.7 0.006 16.6 0.3 13.5 16 0 0 16 16 14 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAK62205.1 - 3.7e-16 57.9 12.8 0.33 11.3 0.0 12.5 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAK62205.1 - 7e-16 57.4 11.6 0.0022 18.3 0.0 11.7 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAK62205.1 - 7.8e-15 55.3 6.4 1.2e-05 25.8 2.1 14.5 10 4 7 18 18 18 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAK62205.1 - 1.1e-13 51.5 39.5 0.00042 20.8 0.0 11.5 9 3 3 13 13 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAK62205.1 - 3.5e-12 46.4 44.2 2.8e-07 30.7 0.0 11.8 11 2 1 12 12 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAK62205.1 - 7.5e-12 44.4 6.2 0.18 11.9 0.1 7.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAK62205.1 - 1.7e-10 40.8 79.8 0.00031 21.3 0.3 18.1 14 6 7 22 22 18 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAK62205.1 - 1.2e-07 31.3 9.8 0.025 14.3 0.1 6.8 6 0 0 6 6 6 2 TPR repeat TPR_9 PF13371.6 GAK62205.1 - 1.5e-06 28.2 27.1 0.71 10.1 0.8 9.8 6 3 2 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK62205.1 - 1.5e-05 25.1 10.3 1.3 9.3 0.0 6.6 5 2 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAK62205.1 - 0.00013 22.4 26.5 0.28 11.9 0.0 11.9 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAK62205.1 - 0.00013 21.7 3.4 2 8.4 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_22 PF18833.1 GAK62205.1 - 0.002 18.2 0.0 0.012 15.7 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 GAK62205.1 - 0.0021 17.1 3.9 0.78 8.6 0.0 4.3 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 ChAPs PF09295.10 GAK62205.1 - 0.016 14.2 0.1 0.075 12.0 0.0 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) FAA_hydrolase_N PF09298.11 GAK62205.1 - 0.17 12.1 1.1 23 5.2 0.0 3.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal Fungal_trans_2 PF11951.8 GAK62207.1 - 1.6e-11 43.6 4.6 5e-06 25.6 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62207.1 - 0.00064 19.8 10.2 0.0011 19.0 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cwf_Cwc_15 PF04889.12 GAK62207.1 - 2.7 7.7 12.6 0.074 12.8 6.0 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mito_carr PF00153.27 GAK62208.1 - 8.5e-40 134.6 7.7 9.4e-18 63.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CTK3 PF12243.8 GAK62209.1 - 5.8e-19 68.3 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 GAK62209.1 - 7.5e-18 64.4 2.8 1.5e-17 63.5 2.8 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus YjeJ PF15922.5 GAK62209.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 YjeJ-like DUF2849 PF11011.8 GAK62209.1 - 4.4 8.0 5.3 14 6.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) PI3Ka PF00613.20 GAK62210.1 - 2e-52 177.3 0.0 3.8e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAK62210.1 - 9e-46 156.7 0.0 3.6e-43 148.2 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAK62210.1 - 1.3e-37 128.8 0.0 3.5e-37 127.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Chromo PF00385.24 GAK62210.1 - 0.00017 21.4 0.1 0.0004 20.2 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain C2 PF00168.30 GAK62210.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 C2 domain PigN PF04987.14 GAK62211.1 - 4.5e-109 365.3 11.7 6.3e-109 364.8 11.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 GAK62211.1 - 4e-06 26.7 0.4 0.00045 19.9 0.1 2.5 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAK62211.1 - 0.0035 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase TPR_MalT PF17874.1 GAK62211.1 - 0.075 12.4 0.7 7.3 5.9 0.1 2.3 1 1 1 2 2 2 0 MalT-like TPR region UQ_con PF00179.26 GAK62212.1 - 3.5e-16 59.1 0.0 4.7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAK62212.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B ABC_membrane PF00664.23 GAK62213.1 - 5.9e-51 173.7 22.6 2.5e-33 115.9 7.4 3.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK62213.1 - 1.1e-49 168.5 0.0 5.9e-27 94.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAK62213.1 - 2.2e-11 43.6 0.2 0.032 13.7 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK62213.1 - 1.2e-07 31.4 0.5 0.0011 18.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 GAK62213.1 - 1.3e-06 28.9 0.2 0.066 13.6 0.1 3.7 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 GAK62213.1 - 2.5e-06 27.5 0.6 0.16 11.7 0.2 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAK62213.1 - 8.8e-05 22.8 0.1 0.38 11.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAK62213.1 - 8.9e-05 22.9 1.0 0.31 11.4 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_24 PF13479.6 GAK62213.1 - 0.00018 21.3 0.1 0.012 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAK62213.1 - 0.00025 21.6 11.2 0.00044 20.8 0.0 3.5 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 GAK62213.1 - 0.00025 21.0 0.5 0.025 14.5 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase T2SSE PF00437.20 GAK62213.1 - 0.00053 19.1 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 GAK62213.1 - 0.00085 18.9 0.1 2.2 7.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 GAK62213.1 - 0.0011 19.0 0.4 1.8 8.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 GAK62213.1 - 0.0027 17.5 0.2 0.96 9.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.23 GAK62213.1 - 0.01 15.9 3.9 0.039 14.0 0.0 3.2 4 0 0 4 4 4 0 Dynamin family IstB_IS21 PF01695.17 GAK62213.1 - 0.011 15.5 0.1 4.2 7.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Lipoxygenase PF00305.19 GAK62213.1 - 0.014 13.8 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipoxygenase FtsK_SpoIIIE PF01580.18 GAK62213.1 - 0.015 14.6 0.2 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 GAK62213.1 - 0.017 14.6 0.1 3 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAK62213.1 - 0.02 14.1 0.0 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 GAK62213.1 - 0.038 13.2 0.1 5.2 6.2 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_18 PF13238.6 GAK62213.1 - 0.059 13.9 0.1 6.2 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAK62213.1 - 0.17 12.0 3.6 3 8.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 GAK62213.1 - 0.18 12.0 0.3 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAK62213.1 - 0.22 11.1 0.9 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAK62213.1 - 0.34 10.8 2.3 9.3 6.1 0.1 2.9 3 0 0 3 3 3 0 NACHT domain DUF87 PF01935.17 GAK62213.1 - 0.5 10.4 6.8 2.9 7.9 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain AP3D1 PF06375.11 GAK62214.1 - 0.098 12.9 0.2 0.098 12.9 0.2 3.2 4 0 0 4 4 4 0 AP-3 complex subunit delta-1 FYDLN_acid PF09538.10 GAK62214.1 - 8.2 7.2 18.3 0.036 14.7 4.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) PPP4R2 PF09184.11 GAK62215.1 - 1.8e-11 44.2 4.3 3e-11 43.4 0.2 2.5 2 1 0 2 2 2 1 PPP4R2 Glyco_hydro_3_C PF01915.22 GAK62216.1 - 2.7e-53 180.9 0.0 5.1e-53 180.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAK62216.1 - 4.8e-39 134.6 0.0 8.2e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAK62216.1 - 2.3e-14 53.2 0.0 4.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cutinase PF01083.22 GAK62217.1 - 8e-21 74.8 1.3 9.2e-21 74.6 1.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAK62217.1 - 0.00013 21.6 0.1 0.00017 21.2 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 GAK62217.1 - 0.098 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PHD PF00628.29 GAK62220.1 - 3.4e-11 42.9 8.0 7.8e-11 41.7 8.0 1.6 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 GAK62220.1 - 0.017 14.9 1.5 0.042 13.6 0.0 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain RAP1 PF07218.11 GAK62220.1 - 3.2 5.9 10.9 5.7 5.1 10.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-HC5HC2H PF13771.6 GAK62220.1 - 7.8 6.8 9.9 24 5.3 9.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain PEX11 PF05648.14 GAK62223.1 - 3.1e-17 62.8 0.0 1.1e-15 57.7 0.0 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HCNGP PF07818.13 GAK62224.1 - 1.6e-16 60.7 0.0 3.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein Ribosomal_L35p PF01632.19 GAK62225.1 - 9.6e-08 32.4 9.4 1.9e-07 31.5 5.5 2.7 2 1 0 2 2 2 1 Ribosomal protein L35 BRE1 PF08647.11 GAK62226.1 - 0.048 13.7 4.6 0.087 12.9 4.6 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Selenoprotein_S PF06936.11 GAK62226.1 - 0.37 10.6 4.5 0.8 9.5 4.5 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) SPA PF08616.10 GAK62227.1 - 1.1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAK62227.1 - 0.0045 15.7 0.0 1.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Transport protein Avl9 DENN PF02141.21 GAK62227.1 - 0.0056 16.7 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain Ribosomal_S9 PF00380.19 GAK62228.1 - 2e-27 96.1 0.2 2.6e-19 69.9 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S9/S16 Ribosomal_L4 PF00573.22 GAK62229.1 - 1e-70 237.3 0.0 1.5e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family KAR9 PF08580.10 GAK62229.1 - 8.3 4.8 7.7 12 4.3 7.7 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SNF2_N PF00176.23 GAK62231.1 - 6.4e-58 196.1 0.0 1.3e-57 195.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 GAK62231.1 - 2e-07 30.8 7.5 4.3e-07 29.7 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK62231.1 - 1e-05 25.3 7.5 1.5e-05 24.8 5.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAK62231.1 - 1.9e-05 24.9 10.3 1.9e-05 24.9 10.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAK62231.1 - 8.5e-05 22.4 6.0 0.0002 21.2 6.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK62231.1 - 0.0001 22.3 8.1 0.00023 21.1 8.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAK62231.1 - 0.00075 19.3 7.4 0.00075 19.3 7.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 GAK62231.1 - 0.0019 18.6 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_5 PF17121.5 GAK62231.1 - 0.0092 15.9 1.3 0.026 14.4 1.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAK62231.1 - 0.35 11.0 7.9 0.87 9.8 7.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 GAK62231.1 - 1.3 8.8 6.8 2.8 7.8 6.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 GAK62231.1 - 1.7 8.5 9.8 0.61 9.9 6.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 GAK62231.1 - 2.1 8.3 8.2 0.99 9.3 5.3 2.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAK62231.1 - 3.4 8.0 6.2 9.8 6.5 6.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain NUFIP1 PF10453.9 GAK62232.1 - 8.8e-13 47.9 3.8 2.3e-12 46.6 3.8 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 GAK62232.1 - 6.6e-06 25.8 2.9 1.1e-05 25.1 2.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 GAK62232.1 - 0.0001 22.1 2.0 0.00022 21.1 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK62232.1 - 0.00025 21.0 3.3 0.00054 19.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 GAK62232.1 - 0.0038 17.9 0.0 0.0038 17.9 0.0 2.3 3 0 0 3 3 3 1 Torus domain CSRNP_N PF16019.5 GAK62232.1 - 3.5 7.5 8.6 0.21 11.5 2.9 1.8 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Abhydrolase_1 PF00561.20 GAK62233.1 - 2.9e-34 118.9 0.2 3.9e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK62233.1 - 1.1e-10 41.2 0.0 7.3e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK62233.1 - 6.3e-10 40.0 2.2 6.3e-10 40.0 2.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 GAK62233.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Ndr family PBD PF00786.28 GAK62234.1 - 0.51 10.7 1.9 1.6 9.1 0.0 2.8 3 0 0 3 3 3 0 P21-Rho-binding domain GCV_T PF01571.21 GAK62235.1 - 2.4e-85 286.0 0.0 3.3e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 GAK62235.1 - 1e-22 79.8 0.1 2.3e-22 78.7 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Glyco_transf_20 PF00982.21 GAK62236.1 - 1.1e-186 621.2 0.0 2.7e-138 461.6 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 GAK62236.1 - 0.014 14.9 0.1 2.5 7.6 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 Lactamase_B PF00753.27 GAK62237.1 - 4.7e-20 72.4 3.4 6.5e-20 72.0 3.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAK62237.1 - 8.3e-06 25.5 0.5 1.3e-05 24.8 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3606 PF12244.8 GAK62237.1 - 0.026 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Fib_alpha PF08702.10 GAK62238.1 - 0.42 10.8 5.3 0.93 9.7 5.3 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 GAK62238.1 - 0.67 8.4 14.2 1.7 7.1 14.2 1.7 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 GAK62238.1 - 6 5.9 14.3 4.8 6.2 12.6 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L36e PF01158.18 GAK62240.1 - 1.9e-39 133.8 4.8 2.7e-39 133.3 4.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e Calcipressin PF04847.12 GAK62241.1 - 7.1e-28 97.6 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Voldacs PF03517.13 GAK62241.1 - 1.3e-24 86.9 1.7 9.7e-23 80.8 0.3 3.2 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling RRM_1 PF00076.22 GAK62241.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GMC_oxred_N PF00732.19 GAK62242.1 - 4.4e-50 170.7 0.0 7e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK62242.1 - 5.5e-34 117.8 0.0 9.3e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAK62242.1 - 3.7e-05 23.1 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK62242.1 - 0.0001 21.6 0.4 0.048 12.7 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAK62242.1 - 0.0006 20.0 0.2 0.0029 17.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAK62242.1 - 0.00081 18.5 0.1 0.0013 17.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAK62242.1 - 0.0013 18.4 1.0 0.081 12.5 0.8 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK62242.1 - 0.17 11.9 0.1 0.44 10.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 GAK62242.1 - 0.17 11.1 0.1 0.36 10.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 GAK62242.1 - 0.19 12.0 0.2 0.4 10.9 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 GAK62242.1 - 0.25 10.1 0.1 0.35 9.7 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase F-actin_cap_A PF01267.17 GAK62243.1 - 5.3e-94 314.6 0.2 6.2e-94 314.3 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit TetR_C_30 PF17939.1 GAK62243.1 - 0.014 15.6 0.2 0.045 14.0 0.2 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_12 PF16914.5 GAK62243.1 - 0.062 13.4 0.7 0.87 9.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal Tim54 PF11711.8 GAK62243.1 - 0.13 11.0 1.2 0.21 10.3 1.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Stimulus_sens_1 PF13756.6 GAK62243.1 - 0.14 12.7 3.6 1.6 9.4 1.3 2.7 2 1 0 2 2 2 0 Stimulus-sensing domain Phosphonate-bd PF12974.7 GAK62244.1 - 0.00075 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 GAK62244.1 - 0.0053 16.7 0.1 0.0096 15.9 0.1 1.4 1 0 0 1 1 1 1 NMT1/THI5 like Tyosinase_C PF18132.1 GAK62244.1 - 0.0058 17.3 0.1 0.027 15.1 0.0 2.0 2 1 0 2 2 2 1 Tyosinase C-terminal domain Pkinase PF00069.25 GAK62245.1 - 1.1e-68 231.4 0.0 1.4e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62245.1 - 7.1e-30 104.2 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK62245.1 - 0.018 14.9 0.1 0.058 13.3 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAK62245.1 - 0.028 13.4 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAK62245.1 - 0.12 11.7 0.1 0.29 10.4 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HA2 PF04408.23 GAK62246.1 - 9.1e-15 54.9 0.0 3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAK62246.1 - 6.7e-11 42.4 0.1 8.6e-10 38.9 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAK62246.1 - 2.8e-10 40.5 0.0 6.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK62246.1 - 5.9e-05 22.9 0.5 0.00025 20.8 0.5 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK62246.1 - 0.00081 19.7 0.0 0.0036 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK62246.1 - 0.00096 19.5 0.1 0.0022 18.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK62246.1 - 0.023 15.1 0.1 0.098 13.0 0.1 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 GAK62246.1 - 0.029 14.1 2.0 0.077 12.7 0.8 2.3 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 GAK62246.1 - 0.051 13.0 0.1 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 GAK62246.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GAK62246.1 - 0.084 13.4 0.3 0.41 11.2 0.3 2.1 1 1 0 1 1 1 0 ABC transporter ResIII PF04851.15 GAK62246.1 - 0.09 12.8 0.1 0.6 10.1 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 GAK62246.1 - 0.49 10.2 1.8 3.7 7.4 0.4 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain ADH_N PF08240.12 GAK62247.1 - 6.2e-27 93.6 1.0 1e-26 92.9 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK62247.1 - 5.6e-12 45.8 0.0 9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAK62247.1 - 2.7e-05 23.8 2.4 0.0068 15.9 2.4 2.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAK62247.1 - 0.0051 17.9 0.0 0.0094 17.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GST_C_3 PF14497.6 GAK62248.1 - 7.7e-20 70.9 0.2 1.6e-19 69.9 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAK62248.1 - 0.094 12.9 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HECT PF00632.25 GAK62249.1 - 7.2e-90 301.6 0.0 1e-89 301.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Methyltransf_28 PF02636.17 GAK62250.1 - 8.3e-39 133.8 0.0 1.7e-38 132.8 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 GAK62250.1 - 0.0016 17.6 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 GAK62250.1 - 0.0058 17.4 0.0 0.017 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain HD_3 PF13023.6 GAK62251.1 - 4.3e-41 140.6 0.1 4.3e-41 140.6 0.1 2.2 2 0 0 2 2 2 1 HD domain DUF1752 PF08550.10 GAK62251.1 - 4.9e-12 45.5 3.0 1.2e-11 44.2 3.0 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) HD_2 PF12917.7 GAK62251.1 - 4.9e-07 29.7 0.1 4.9e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 HD containing hydrolase-like enzyme DUF853 PF05872.12 GAK62251.1 - 2.9 6.4 7.7 46 2.4 6.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Peptidase_C48 PF02902.19 GAK62252.1 - 1e-27 97.4 0.0 8e-19 68.3 0.0 3.1 3 1 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain ADH_N PF08240.12 GAK62253.1 - 9.5e-28 96.3 0.2 2.3e-27 95.0 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK62253.1 - 1.3e-19 70.4 2.6 6.8e-19 68.1 2.6 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAK62253.1 - 6.8e-08 32.3 0.5 0.0094 15.5 0.0 3.0 2 1 1 3 3 3 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAK62253.1 - 0.00043 21.4 0.0 0.0027 18.8 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAK62253.1 - 0.039 13.3 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.13 GAK62253.1 - 0.062 12.7 0.7 0.097 12.0 0.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_M43 PF05572.13 GAK62254.1 - 5.9e-16 58.8 0.0 1.2e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAK62254.1 - 0.00018 21.7 0.5 0.00036 20.7 0.3 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 GAK62254.1 - 0.00077 19.3 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 GAK62254.1 - 0.0021 18.6 2.1 0.0057 17.2 0.3 2.5 1 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAK62254.1 - 0.058 13.0 2.4 0.081 12.6 0.2 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 GAK62254.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF1115 PF06544.12 GAK62255.1 - 5.5e-06 26.5 0.0 9.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Ribosomal_L13 PF00572.18 GAK62257.1 - 5.7e-53 178.4 0.6 8.9e-53 177.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 Iso_dh PF00180.20 GAK62258.1 - 1e-85 288.0 0.0 1.2e-85 287.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF166 PF02593.14 GAK62258.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function MAPEG PF01124.18 GAK62259.1 - 2e-15 56.9 4.7 2.5e-15 56.5 4.7 1.1 1 0 0 1 1 1 1 MAPEG family HTH_Tnp_Tc5 PF03221.16 GAK62260.1 - 2.7e-13 49.7 0.0 5.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 GAK62260.1 - 0.00043 19.8 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 GAK62260.1 - 0.1 12.7 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_L7Ae PF01248.26 GAK62261.1 - 7.4e-21 73.7 0.7 1.4e-20 72.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ldh_1_C PF02866.18 GAK62262.1 - 1e-48 165.5 0.1 1.9e-48 164.6 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAK62262.1 - 4e-45 153.4 0.1 5.6e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAK62262.1 - 7.8e-05 21.8 0.0 0.00018 20.6 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 GAK62262.1 - 0.0033 16.8 0.4 0.13 11.6 0.0 2.6 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 GAK62262.1 - 0.013 15.9 0.1 0.046 14.2 0.0 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 GAK62262.1 - 0.16 11.5 0.2 0.73 9.4 0.1 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Zn_clus PF00172.18 GAK62263.1 - 1.2e-06 28.5 10.3 2e-06 27.8 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK62263.1 - 0.00053 19.1 0.0 0.0054 15.8 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 GAK62265.1 - 2.2e-16 60.7 0.0 2.2e-16 60.7 0.0 4.0 3 2 0 3 3 3 1 SET domain AWS PF17907.1 GAK62265.1 - 4.1e-12 45.9 4.2 4.1e-12 45.9 4.2 1.7 2 0 0 2 2 2 1 AWS domain DUF3072 PF11272.8 GAK62265.1 - 0.059 13.3 0.9 0.25 11.3 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) PHD PF00628.29 GAK62266.1 - 3.5e-06 26.8 18.7 5.9e-06 26.1 18.7 1.4 1 0 0 1 1 1 1 PHD-finger Aldolase_II PF00596.21 GAK62268.1 - 7.2e-43 146.7 0.0 9.2e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MitMem_reg PF13012.6 GAK62269.1 - 0.026 14.9 0.2 0.034 14.6 0.2 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Fib_alpha PF08702.10 GAK62269.1 - 0.031 14.5 1.5 0.043 14.0 1.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.6 GAK62269.1 - 0.033 13.8 0.1 0.037 13.6 0.1 1.1 1 0 0 1 1 1 0 TMCO5 family Jnk-SapK_ap_N PF09744.9 GAK62269.1 - 0.039 14.2 2.1 0.053 13.8 2.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 NPA PF16469.5 GAK62269.1 - 0.062 13.9 0.3 0.09 13.4 0.3 1.3 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 GIT_CC PF16559.5 GAK62269.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Bacillus_HBL PF05791.11 GAK62269.1 - 0.18 11.6 2.1 0.24 11.2 2.1 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Trimer_CC PF08954.11 GAK62269.1 - 1.1 8.8 5.1 0.28 10.8 0.7 2.3 3 0 0 3 3 3 0 Trimerisation motif Ferritin_2 PF13668.6 GAK62271.1 - 9.2e-18 64.8 0.1 1.3e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain DSHCT PF08148.12 GAK62273.1 - 3.6e-49 166.6 0.5 1e-48 165.1 0.5 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 GAK62273.1 - 3.1e-36 124.1 0.0 5.9e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 GAK62273.1 - 1.9e-27 96.9 0.2 3.4e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 GAK62273.1 - 1.1e-19 70.8 0.0 2.7e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAK62273.1 - 5.4e-07 29.8 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAK62273.1 - 6.1e-06 26.5 0.0 1.9e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain LOH1CR12 PF10158.9 GAK62273.1 - 0.09 12.8 1.0 0.7 9.9 0.1 2.4 2 0 0 2 2 2 0 Tumour suppressor protein CT_C_D PF02682.16 GAK62273.1 - 0.11 12.2 0.1 0.35 10.6 0.1 1.8 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D AAA_22 PF13401.6 GAK62273.1 - 0.13 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF952 PF06108.12 GAK62274.1 - 1.4e-15 57.0 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Mit_KHE1 PF10173.9 GAK62275.1 - 8e-58 195.7 1.3 1.4e-57 194.9 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Lectin_C PF00059.21 GAK62275.1 - 0.046 14.4 0.0 0.094 13.5 0.0 1.5 1 0 0 1 1 1 0 Lectin C-type domain DND1_DSRM PF14709.7 GAK62275.1 - 2.4 8.5 5.0 25 5.2 0.0 3.5 4 0 0 4 4 4 0 double strand RNA binding domain from DEAD END PROTEIN 1 PCP_red PF08369.10 GAK62275.1 - 2.6 8.3 6.0 0.99 9.7 0.3 2.5 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Nbl1_Borealin_N PF10444.9 GAK62276.1 - 2.6e-15 55.8 2.3 5.1e-15 54.9 2.3 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal CEP63 PF17045.5 GAK62276.1 - 0.022 14.7 3.7 0.035 14.0 3.6 1.4 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Dfp1_Him1_M PF08630.10 GAK62277.1 - 2.1e-34 118.5 0.0 6.1e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 GAK62277.1 - 3.2e-19 68.8 0.8 5.8e-19 67.9 0.8 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 GAK62277.1 - 0.0094 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Arf PF00025.21 GAK62278.1 - 2.5e-79 264.8 0.1 2.8e-79 264.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAK62278.1 - 1.3e-14 54.4 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAK62278.1 - 3.6e-14 52.6 0.0 4.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAK62278.1 - 7.8e-13 48.3 0.0 8.3e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAK62278.1 - 8.7e-13 48.1 1.2 5.9e-09 35.5 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAK62278.1 - 2e-10 40.4 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK62278.1 - 2.7e-06 27.5 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAK62278.1 - 0.0067 15.8 0.4 0.021 14.1 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_CH_N PF12471.8 GAK62279.1 - 1.1e-88 296.1 0.0 1.6e-88 295.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 GAK62279.1 - 5.3e-13 48.9 0.0 8.3e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II PA PF02225.22 GAK62279.1 - 0.088 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 PA domain DUF4462 PF14692.6 GAK62282.1 - 3.7 7.1 5.2 3.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4462) WSC PF01822.19 GAK62283.1 - 0.044 14.0 2.7 0.084 13.1 2.7 1.5 1 0 0 1 1 1 0 WSC domain Thg1 PF04446.12 GAK62284.1 - 3.6e-47 159.5 0.0 5.3e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 GAK62284.1 - 4.2e-45 152.8 0.3 9.8e-45 151.7 0.3 1.6 1 1 0 1 1 1 1 Thg1 C terminal domain Ferric_reduct PF01794.19 GAK62285.1 - 4.6e-21 75.2 15.9 4.6e-21 75.2 15.9 2.5 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAK62285.1 - 1e-13 51.3 0.0 2.2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAK62285.1 - 2.4e-11 44.0 0.0 3.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NmrA PF05368.13 GAK62286.1 - 4.1e-13 49.4 0.0 5.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAK62286.1 - 4.2e-13 49.6 0.0 6.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAK62286.1 - 1.5e-11 44.3 0.1 7.8e-11 41.9 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK62286.1 - 4.5e-10 39.0 0.0 1.2e-09 37.6 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAK62286.1 - 8.6e-09 34.9 0.0 1.8e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAK62286.1 - 3.7e-06 26.3 0.1 0.08 12.1 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 GAK62286.1 - 1.2e-05 24.8 0.1 2.9e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GAK62286.1 - 0.00012 21.6 0.0 0.00057 19.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK62286.1 - 0.00031 20.4 0.0 0.0032 17.1 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK62286.1 - 0.016 15.2 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 GAK62286.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 GAK62286.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HhH-GPD PF00730.25 GAK62287.1 - 7.4e-12 45.7 0.0 1.3e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein eIF3_N PF09440.10 GAK62288.1 - 8.9e-45 152.4 0.4 2.2e-44 151.1 0.4 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GAK62288.1 - 1.3e-10 41.7 0.1 5.2e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 PCI domain MFS_1 PF07690.16 GAK62289.1 - 8.8e-12 44.6 10.9 8.8e-12 44.6 10.9 2.9 2 2 0 2 2 2 1 Major Facilitator Superfamily Med13_C PF06333.12 GAK62289.1 - 0.15 11.3 1.3 0.52 9.5 1.5 1.5 1 1 1 2 2 2 0 Mediator complex subunit 13 C-terminal domain LtrA PF06772.11 GAK62290.1 - 4.4e-31 108.4 25.2 5.8e-31 108.0 25.2 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1211 PF06736.11 GAK62290.1 - 0.34 11.4 4.8 1.4 9.4 3.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) Zn_clus PF00172.18 GAK62291.1 - 2.5e-06 27.5 13.6 5.5e-06 26.4 13.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK62291.1 - 0.031 13.3 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain UCH PF00443.29 GAK62292.1 - 3.9e-51 174.0 0.0 5.4e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK62292.1 - 1.4e-27 97.2 0.1 1.9e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Raffinose_syn PF05691.12 GAK62292.1 - 7.5e-22 76.9 0.0 1.6e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 DUF3168 PF11367.8 GAK62292.1 - 0.087 13.0 0.5 0.91 9.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) MFS_1 PF07690.16 GAK62293.1 - 6.8e-32 110.8 20.2 6.8e-32 110.8 20.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAK62293.1 - 1e-07 31.2 1.5 1.8e-07 30.3 1.5 1.4 1 1 0 1 1 1 1 MFS_1 like family OATP PF03137.20 GAK62293.1 - 0.025 12.9 0.2 0.025 12.9 0.2 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Vpu PF00558.19 GAK62293.1 - 0.18 11.6 0.6 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Vpu protein EXS PF03124.14 GAK62293.1 - 0.38 10.0 9.1 0.024 14.0 1.0 2.4 1 1 1 3 3 3 0 EXS family DASH_Dad4 PF08650.10 GAK62294.1 - 4.1e-25 87.6 3.2 4.6e-25 87.4 3.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Ins134_P3_kin PF05770.11 GAK62294.1 - 0.034 13.6 0.1 0.038 13.5 0.1 1.0 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain E1-E2_ATPase PF00122.20 GAK62295.1 - 2.9e-21 75.8 0.0 7.6e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAK62295.1 - 1.3e-15 58.2 0.0 2.8e-08 34.3 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAK62295.1 - 0.0062 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAK62295.1 - 0.024 14.4 0.0 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK62295.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Bac_rhodopsin PF01036.18 GAK62296.1 - 2.6e-44 151.5 15.4 3.4e-44 151.1 15.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein ResIII PF04851.15 GAK62296.1 - 0.27 11.2 0.6 0.45 10.5 0.6 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arteri_Gl PF00951.18 GAK62296.1 - 1.3 8.8 7.4 0.087 12.6 0.6 2.0 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein SUR7 PF06687.12 GAK62296.1 - 1.5 8.4 7.5 0.52 9.9 0.2 2.3 2 0 0 2 2 2 0 SUR7/PalI family UQ_con PF00179.26 GAK62297.1 - 9.4e-41 138.7 0.0 1.1e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAK62297.1 - 0.00089 19.5 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 GAK62297.1 - 0.0061 16.2 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 GAK62297.1 - 0.055 13.2 0.0 0.065 12.9 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B PLDc PF00614.22 GAK62298.1 - 4.1e-15 55.2 0.2 2.1e-06 27.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAK62298.1 - 6.6e-13 48.7 0.0 2e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 GAK62298.1 - 3.5e-10 39.9 0.0 1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 PX domain PH PF00169.29 GAK62298.1 - 1.5 9.3 3.6 12 6.4 0.6 3.6 3 1 0 3 3 3 0 PH domain Rrp15p PF07890.12 GAK62299.1 - 2e-32 112.3 6.1 2e-32 112.3 6.1 2.5 1 1 1 2 2 2 1 Rrp15p ATP-grasp_2 PF08442.10 GAK62300.1 - 2.4e-71 239.5 0.9 3.4e-71 239.0 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 GAK62300.1 - 5.2e-22 78.3 1.1 1.2e-21 77.1 0.7 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 GAK62300.1 - 4.7e-12 45.8 0.8 8.6e-12 45.0 0.2 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 GAK62300.1 - 0.00021 21.1 1.0 0.00043 20.1 0.2 2.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 GAK62300.1 - 0.011 15.3 0.0 0.033 13.7 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain PASTA PF03793.19 GAK62300.1 - 0.19 11.6 0.3 1 9.3 0.1 2.3 2 0 0 2 2 2 0 PASTA domain Ceramidase_alk PF04734.13 GAK62301.1 - 3.1e-179 596.9 0.0 8.4e-178 592.1 0.0 2.1 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GAK62301.1 - 1.6e-42 145.2 2.2 5.5e-33 114.2 2.6 2.5 1 1 1 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, C-terminal MCM PF00493.23 GAK62302.1 - 4.1e-103 343.3 0.8 6e-103 342.8 0.8 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAK62302.1 - 7.7e-41 138.9 0.9 1.5e-40 137.9 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 GAK62302.1 - 1.1e-29 102.9 0.7 1.1e-29 102.9 0.7 1.8 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 GAK62302.1 - 8.6e-26 90.2 1.6 1.6e-25 89.3 0.4 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 GAK62302.1 - 2.7e-20 72.9 0.1 1.1e-19 71.0 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAK62302.1 - 1.5e-07 31.0 0.0 7.4e-07 28.8 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAK62302.1 - 0.0019 18.0 0.0 0.0061 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAK62302.1 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Succ_DH_flav_C PF02910.20 GAK62302.1 - 0.015 15.2 0.2 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term AAA_5 PF07728.14 GAK62302.1 - 0.033 14.2 0.0 0.14 12.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Nop PF01798.18 GAK62305.1 - 4.6e-70 235.7 0.0 6.7e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GAK62305.1 - 1.4e-38 132.5 5.2 1.4e-38 132.5 5.2 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain AMP-binding PF00501.28 GAK62306.1 - 5.1e-83 279.0 0.0 9e-83 278.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK62306.1 - 3.7e-19 69.5 0.1 1.5e-18 67.5 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 GAK62306.1 - 7.8e-17 61.5 0.9 7.8e-17 61.5 0.9 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ACAS_N PF16177.5 GAK62306.1 - 3e-14 52.7 0.1 9.1e-14 51.1 0.1 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ADH_zinc_N_2 PF13602.6 GAK62306.1 - 3.6e-08 34.5 1.0 1.1e-07 32.9 0.1 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK62306.1 - 0.0019 18.0 0.6 0.016 15.1 0.0 2.9 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 GAK62306.1 - 0.056 13.6 0.1 0.22 11.7 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MOSC PF03473.17 GAK62307.1 - 5.1e-22 78.3 0.0 8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAK62307.1 - 4.3e-19 68.5 0.0 9e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Cytochrom_D1 PF02239.16 GAK62307.1 - 0.071 11.6 0.0 0.096 11.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome D1 heme domain CorA PF01544.18 GAK62308.1 - 1.6e-44 152.4 0.2 2.4e-44 151.8 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 GAK62308.1 - 0.11 12.6 0.9 0.24 11.4 0.9 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SUR7 PF06687.12 GAK62310.1 - 1.1e-25 90.6 2.3 1.8e-25 89.8 2.3 1.4 1 0 0 1 1 1 1 SUR7/PalI family MIT PF04212.18 GAK62311.1 - 1.4e-08 34.7 0.2 2.8e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Spo7 PF03907.13 GAK62312.1 - 2.1 7.7 7.5 0.2 11.1 2.4 1.8 2 0 0 2 2 2 0 Spo7-like protein DUF2723 PF11028.8 GAK62312.1 - 3.4 7.5 13.4 0.57 10.1 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) DIL PF01843.19 GAK62313.1 - 8.7e-30 103.1 1.2 2.1e-29 101.9 1.2 1.7 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 GAK62313.1 - 1.4e-11 44.6 0.0 3e-05 24.5 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK62313.1 - 7.8e-11 42.4 0.0 6e-10 39.6 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAK62313.1 - 4.6e-08 32.7 0.0 0.00044 20.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAK62313.1 - 3.9e-07 30.2 0.0 5.4e-05 23.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 GAK62313.1 - 0.00031 21.0 0.0 0.04 14.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF4746 PF15928.5 GAK62313.1 - 1.5 8.1 4.6 2.6 7.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SGT1 PF07093.11 GAK62314.1 - 4.6e-78 263.1 7.5 9.8e-55 186.1 0.1 2.8 3 0 0 3 3 3 2 SGT1 protein PG_binding_2 PF08823.11 GAK62314.1 - 0.0064 16.8 0.1 0.02 15.2 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain ANAPC4 PF12896.7 GAK62314.1 - 0.089 12.3 0.2 7.9 5.9 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 Peptidase_C48 PF02902.19 GAK62315.1 - 6.1e-39 134.1 0.0 1.4e-35 123.1 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Nitr_red_bet_C PF14711.6 GAK62315.1 - 0.054 13.2 0.2 7.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal ANAPC9 PF12856.7 GAK62315.1 - 0.22 11.7 2.5 0.78 9.9 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 9 Cupin_8 PF13621.6 GAK62316.1 - 3.1e-22 79.5 0.3 4.6e-22 79.0 0.3 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 GAK62316.1 - 1.2e-15 58.0 0.5 2.9e-15 56.7 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.11 GAK62316.1 - 0.0095 15.2 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 GAK62316.1 - 0.016 14.9 0.0 0.046 13.4 0.0 1.8 1 0 0 1 1 1 0 Cupin domain UPF0061 PF02696.14 GAK62317.1 - 3.2e-96 322.9 0.0 4.7e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GNAT_acetyltr_2 PF13718.6 GAK62317.1 - 0.082 12.3 0.1 0.082 12.3 0.1 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Mannosyl_trans PF05007.13 GAK62318.1 - 6e-59 200.0 21.0 4.9e-57 193.8 13.7 2.5 3 0 0 3 3 3 2 Mannosyltransferase (PIG-M) PNTB_4TM PF12769.7 GAK62318.1 - 0.2 12.2 1.5 0.45 11.0 0.2 2.2 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch p450 PF00067.22 GAK62319.1 - 3.2e-53 181.1 0.0 3.9e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SLX9 PF15341.6 GAK62320.1 - 1.1e-20 74.3 9.0 2e-20 73.5 9.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 RNA_pol_3_Rpc31 PF11705.8 GAK62320.1 - 0.036 14.3 7.6 0.067 13.4 7.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4335 PF14233.6 GAK62320.1 - 0.042 13.8 0.3 0.06 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Astro_capsid_p PF12226.8 GAK62320.1 - 0.11 11.7 4.6 0.17 11.0 4.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SAPS PF04499.15 GAK62320.1 - 0.62 8.8 6.3 0.76 8.5 6.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hamartin PF04388.12 GAK62320.1 - 0.69 8.5 9.4 0.79 8.3 9.4 1.0 1 0 0 1 1 1 0 Hamartin protein Lipase_3 PF01764.25 GAK62321.1 - 1.2e-17 64.1 0.0 3.3e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Hydrolase_4 PF12146.8 GAK62321.1 - 0.027 13.8 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TFCD_C PF12612.8 GAK62322.1 - 5.8e-35 120.8 0.0 1.9e-33 115.9 0.0 3.2 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 GAK62322.1 - 0.0015 18.7 0.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 GAK62322.1 - 0.011 16.3 0.0 5.5 7.7 0.0 4.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAK62322.1 - 0.029 14.6 21.1 0.073 13.4 0.1 8.1 8 0 0 8 8 8 0 HEAT repeat FATC PF02260.20 GAK62322.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 FATC domain HEAT_2 PF13646.6 GAK62322.1 - 0.69 10.3 0.0 0.69 10.3 0.0 6.9 7 1 0 7 7 7 0 HEAT repeats Methyltransf_23 PF13489.6 GAK62323.1 - 1.4e-15 57.5 0.3 2.1e-15 57.0 0.3 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK62323.1 - 2.5e-14 53.8 0.0 5.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK62323.1 - 2.2e-13 50.7 0.0 6e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK62323.1 - 2.9e-12 47.1 0.1 9.3e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK62323.1 - 1.8e-11 44.1 0.0 2.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK62323.1 - 5.9e-06 25.9 0.1 1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 GAK62323.1 - 3e-05 23.2 0.0 0.0003 20.0 0.0 2.0 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 GAK62323.1 - 5.4e-05 22.6 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 GAK62323.1 - 8.7e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) NPV_P10 PF05531.12 GAK62323.1 - 0.0038 17.6 0.4 0.0085 16.5 0.4 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein RrnaAD PF00398.20 GAK62323.1 - 0.0041 16.2 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 GAK62323.1 - 0.0069 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) DRE2_N PF16803.5 GAK62323.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Cons_hypoth95 PF03602.15 GAK62323.1 - 0.034 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TehB PF03848.14 GAK62323.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB SelP_N PF04592.14 GAK62323.1 - 1.6 8.1 12.1 9.1 5.6 12.0 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Flavin_Reduct PF01613.18 GAK62324.1 - 1.9e-18 67.0 0.1 3e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain AA_permease PF00324.21 GAK62326.1 - 8.3e-136 453.4 42.0 1.1e-135 453.0 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK62326.1 - 6.4e-42 143.9 44.6 8.7e-42 143.4 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease ACT_7 PF13840.6 GAK62328.1 - 2.6e-16 59.2 0.0 8.2e-16 57.6 0.0 1.7 2 0 0 2 2 2 1 ACT domain Glyoxalase_4 PF13669.6 GAK62328.1 - 0.16 12.3 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily XAP5 PF04921.14 GAK62329.1 - 1.5e-85 287.0 7.6 1.5e-85 287.0 7.6 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator Glyco_transf_22 PF03901.17 GAK62330.1 - 2.3e-30 106.2 10.0 3.2e-30 105.7 10.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Cm_res_leader PF08077.11 GAK62330.1 - 0.2 11.8 1.1 4.6 7.7 0.0 3.7 3 0 0 3 3 3 0 Chloramphenicol resistance gene leader peptide Syntaxin-18_N PF10496.9 GAK62331.1 - 6.1e-16 58.4 2.4 3.2e-15 56.1 0.0 3.0 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF5089 PF17002.5 GAK62331.1 - 0.011 15.6 0.9 0.03 14.2 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) SNARE PF05739.19 GAK62331.1 - 0.021 14.8 0.0 0.097 12.7 0.0 2.1 2 0 0 2 2 2 0 SNARE domain Latarcin PF10279.9 GAK62331.1 - 0.21 12.0 1.8 7.1 7.1 0.4 2.7 2 0 0 2 2 2 0 Latarcin precursor UQ_con PF00179.26 GAK62332.1 - 4.3e-44 149.6 0.0 5.9e-44 149.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 GAK62333.1 - 7.2e-35 120.6 0.0 1.9e-20 73.4 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62333.1 - 1.7e-17 63.6 0.0 1.5e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SCHIP-1 PF10148.9 GAK62334.1 - 0.15 11.7 0.5 0.2 11.3 0.5 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 IQCJ-SCHIP1 PF15157.6 GAK62334.1 - 0.93 9.3 3.3 1.3 8.9 3.3 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Sec1 PF00995.23 GAK62335.1 - 9.5e-121 404.8 0.0 1.1e-120 404.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family 4HBT_3 PF13622.6 GAK62336.1 - 9.5e-58 196.4 0.2 1.4e-57 195.8 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 GAK62336.1 - 2.7e-30 104.9 0.0 8.8e-24 83.8 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase Nup88 PF10168.9 GAK62337.1 - 1.3e-19 69.6 0.1 8.9e-16 56.9 0.0 3.3 3 0 0 3 3 3 2 Nuclear pore component Nup54 PF13874.6 GAK62337.1 - 0.03 14.4 2.9 0.18 11.9 2.9 2.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TPR_2 PF07719.17 GAK62338.1 - 3e-18 64.4 12.4 0.056 13.6 0.1 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAK62338.1 - 2.8e-16 59.9 2.8 0.00046 20.8 0.1 6.8 7 1 0 8 8 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAK62338.1 - 5.3e-15 54.3 8.1 0.51 10.7 0.1 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAK62338.1 - 6.3e-14 52.2 13.2 4.4e-05 23.9 0.2 8.2 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAK62338.1 - 3.5e-12 46.4 21.1 3.7e-05 23.9 0.8 7.2 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAK62338.1 - 1.1e-11 44.1 10.4 0.27 11.1 0.1 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAK62338.1 - 8.5e-10 38.2 0.0 0.022 14.4 0.0 4.7 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 GAK62338.1 - 1.3e-07 31.8 15.2 0.0017 19.0 1.4 8.8 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAK62338.1 - 4.2e-07 30.2 7.0 1.7 9.4 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAK62338.1 - 1.2e-06 28.5 0.3 0.13 12.7 0.0 5.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAK62338.1 - 8.6e-05 21.9 4.4 0.0083 15.4 1.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK62338.1 - 0.0002 21.5 6.8 0.045 13.9 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAK62338.1 - 0.00094 19.5 5.2 0.92 9.9 0.0 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK62338.1 - 0.0044 17.2 3.5 1.4 9.2 2.1 4.3 3 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAK62338.1 - 0.0051 16.8 12.1 6.8 7.0 0.1 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat NARP1 PF12569.8 GAK62338.1 - 0.13 11.2 3.9 0.73 8.7 0.3 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Vps39_1 PF10366.9 GAK62338.1 - 0.16 12.3 0.0 6.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 BTAD PF03704.17 GAK62338.1 - 0.76 10.2 12.4 1.5 9.3 2.2 3.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 GAK62338.1 - 1.9 9.4 12.0 14 6.6 0.2 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAK62338.1 - 3.2 7.7 12.4 48 4.0 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat Sld5 PF05916.11 GAK62340.1 - 5.4e-12 46.2 0.1 8.8e-12 45.5 0.1 1.4 1 1 0 1 1 1 1 GINS complex protein Pox_A3L PF05288.11 GAK62340.1 - 0.17 11.9 0.0 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A3L Protein Glyco_hydro_16 PF00722.21 GAK62341.1 - 2.2e-29 102.2 7.7 4.7e-29 101.1 7.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 GAK62341.1 - 0.00025 21.5 13.1 0.00055 20.4 13.1 1.5 1 0 0 1 1 1 1 Chitin recognition protein Sec10 PF07393.11 GAK62342.1 - 3.4e-280 931.5 0.0 4.2e-280 931.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1664 PF07889.12 GAK62342.1 - 0.069 13.2 0.7 0.19 11.8 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 GAK62342.1 - 0.18 10.6 0.2 0.34 9.7 0.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CTD_bind PF04818.13 GAK62342.1 - 0.23 12.3 0.7 4.8 8.1 0.0 3.3 4 0 0 4 4 4 0 RNA polymerase II-binding domain. IFT20 PF14931.6 GAK62342.1 - 5.7 7.1 5.9 0.47 10.6 0.4 2.1 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 RIX1 PF08167.12 GAK62343.1 - 8.3e-39 133.3 5.4 1.6e-37 129.1 3.3 2.5 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis DnaJ PF00226.31 GAK62344.1 - 2.7e-17 62.6 0.0 5.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain PBP PF01161.20 GAK62345.1 - 9e-08 32.5 0.0 1.4e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pex2_Pex12 PF04757.14 GAK62346.1 - 1.3e-32 113.2 4.0 2e-32 112.6 4.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 GAK62346.1 - 0.00023 20.9 1.0 0.0053 16.6 0.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK62346.1 - 0.00035 20.5 0.2 0.0077 16.2 0.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAK62346.1 - 0.003 17.4 1.7 0.0082 16.0 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAK62346.1 - 0.026 14.9 0.5 0.68 10.3 0.1 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 GAK62346.1 - 0.16 12.0 2.1 0.4 10.7 0.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Acid_PPase PF12689.7 GAK62347.1 - 5.8e-55 185.7 0.0 7.7e-55 185.3 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase DUF903 PF06004.12 GAK62347.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) Hydrolase PF00702.26 GAK62347.1 - 0.097 12.9 0.0 0.71 10.1 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAK62347.1 - 0.18 11.9 0.0 1.4 9.0 0.0 2.1 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MOR2-PAG1_N PF14222.6 GAK62348.1 - 6.2e-129 431.5 0.0 1.1e-128 430.7 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 GAK62348.1 - 2.3e-93 312.7 0.2 2.1e-91 306.3 0.0 3.3 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 GAK62348.1 - 1.2e-31 109.3 3.3 1.6e-14 52.6 0.0 4.1 3 1 1 4 4 4 4 Cell morphogenesis central region HEAT_EZ PF13513.6 GAK62348.1 - 0.011 16.2 0.1 5.1 7.7 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat Laminin_I PF06008.14 GAK62348.1 - 0.12 12.1 0.3 16 5.1 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain I HEAT_2 PF13646.6 GAK62348.1 - 2.4 8.6 13.1 1.8 9.0 0.0 6.6 8 0 0 8 8 8 0 HEAT repeats LCAT PF02450.15 GAK62349.1 - 6.1e-91 305.5 0.0 1.7e-90 304.1 0.0 1.6 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Serglycin PF04360.12 GAK62349.1 - 0.0022 17.9 6.9 0.0037 17.2 5.8 1.8 2 0 0 2 2 2 1 Serglycin Lipase_2 PF01674.18 GAK62349.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) DWNN PF08783.11 GAK62350.1 - 6.3e-35 119.3 0.0 1.2e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 GAK62350.1 - 1.9e-10 40.3 4.8 3.6e-10 39.5 4.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAK62350.1 - 6.2e-06 26.1 0.9 1.3e-05 25.1 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 GAK62350.1 - 0.00025 21.2 0.1 0.018 15.2 0.0 2.5 1 1 1 2 2 2 1 U-box domain zf-CCHC_3 PF13917.6 GAK62350.1 - 0.00035 20.5 0.7 0.0013 18.7 0.7 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 GAK62350.1 - 0.012 15.3 0.5 0.039 13.7 0.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger TetR_C_23 PF17931.1 GAK62350.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-RING_2 PF13639.6 GAK62350.1 - 0.42 11.0 12.2 0.93 9.9 12.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 GAK62350.1 - 2 8.3 18.1 0.1 12.5 12.3 1.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAK62350.1 - 3.5 7.9 14.0 9.3 6.5 14.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAK62350.1 - 8.2 6.4 15.4 16 5.5 15.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.16 GAK62350.1 - 9.2 6.9 6.8 24 5.6 6.8 1.7 1 0 0 1 1 1 0 Trm112p-like protein zf-C3HC4_2 PF13923.6 GAK62350.1 - 9.5 6.2 21.9 0.11 12.3 14.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CLTH PF10607.9 GAK62351.1 - 3e-30 105.1 0.0 4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAK62351.1 - 1.5e-09 37.4 2.1 1.6e-09 37.4 0.0 2.2 3 0 0 3 3 3 1 LisH HEAT_2 PF13646.6 GAK62352.1 - 1.2e-25 89.7 2.4 8.1e-14 51.8 1.5 2.7 2 1 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 GAK62352.1 - 2.8e-19 67.8 1.2 0.00061 20.2 0.0 6.8 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 GAK62352.1 - 4.3e-14 51.4 3.4 0.087 13.1 0.0 6.4 7 0 0 7 7 7 4 HEAT repeat Arm PF00514.23 GAK62352.1 - 0.00048 20.1 0.1 1.8 8.7 0.0 4.0 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 GAK62352.1 - 0.0029 17.9 2.1 0.012 15.9 0.1 3.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 GAK62352.1 - 0.0051 16.9 0.1 2.6 8.1 0.0 3.5 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAK62352.1 - 0.0072 16.8 3.9 28 5.4 0.0 4.7 2 2 3 5 5 5 0 HEAT-like repeat UPF0147 PF03685.13 GAK62352.1 - 0.023 14.7 0.2 8 6.6 0.0 3.3 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0147) IFRD PF05004.13 GAK62352.1 - 0.03 13.4 0.7 9.4 5.2 0.0 3.0 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) RL10P_insert PF17777.1 GAK62353.1 - 2.7e-21 75.4 0.1 4e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAK62353.1 - 1.2e-18 67.1 0.0 2.3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 NOA36 PF06524.12 GAK62353.1 - 0.73 9.1 12.6 1.1 8.5 12.6 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 GAK62353.1 - 1.6 9.2 9.5 4 7.9 9.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal S-antigen PF05756.11 GAK62353.1 - 3.9 7.9 4.9 8.4 6.8 4.9 1.6 1 0 0 1 1 1 0 S-antigen protein F-box-like PF12937.7 GAK62354.1 - 0.015 15.2 1.6 0.13 12.2 0.3 2.6 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 GAK62354.1 - 0.51 10.2 1.5 0.67 9.8 0.0 2.0 3 0 0 3 3 3 0 F-box Zn_clus PF00172.18 GAK62356.1 - 6.8e-10 38.9 26.5 5.1e-08 32.9 8.3 3.0 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain COA2 PF17051.5 GAK62356.1 - 0.14 12.3 0.3 0.38 10.8 0.3 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 BATS PF06968.13 GAK62357.1 - 1.1e-18 67.2 0.3 2.9e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GAK62357.1 - 1.4e-14 54.9 0.1 2.7e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily FeoB_associated PF12669.7 GAK62357.1 - 0.82 10.1 2.8 2.2 8.8 2.8 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DEAD PF00270.29 GAK62358.1 - 1.1e-50 171.8 0.0 5e-50 169.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK62358.1 - 8.4e-25 87.3 0.0 2.6e-12 47.1 0.0 3.4 3 1 1 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAK62358.1 - 2.9e-06 27.4 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAK62358.1 - 0.017 14.8 0.0 1.5 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAK62358.1 - 0.093 13.1 0.0 18 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1776 PF08643.10 GAK62359.1 - 2.3e-05 23.9 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.25 GAK62359.1 - 0.0059 16.1 0.0 0.093 12.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PRIMA1 PF16101.5 GAK62359.1 - 0.072 13.1 3.0 0.29 11.2 3.0 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Asn_synthase PF00733.21 GAK62360.1 - 1.1e-91 308.1 1.4 7.3e-56 190.3 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 GAK62360.1 - 1.6e-37 128.2 0.0 2.5e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAK62360.1 - 2.6e-30 105.3 0.0 5.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAK62360.1 - 3.7e-05 23.3 0.0 9.9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAK62360.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD synthase WD40 PF00400.32 GAK62361.1 - 1.4e-12 47.8 3.1 0.0057 17.5 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK62361.1 - 1.6e-06 28.3 0.0 0.004 17.4 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AP_endonuc_2 PF01261.24 GAK62363.1 - 2.3e-29 102.3 0.0 4.1e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAAD PF18752.1 GAK62363.1 - 0.97 9.2 6.5 0.8 9.5 5.2 1.5 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase Glyco_trans_4_4 PF13579.6 GAK62364.1 - 1.7 9.0 8.3 0.063 13.7 1.3 1.9 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain PRP21_like_P PF12230.8 GAK62365.1 - 1.1e-41 143.2 1.1 1.1e-41 143.2 1.1 2.4 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 GAK62365.1 - 7.7e-30 102.7 2.6 2.6e-14 52.9 0.1 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 GAK62365.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Toprim_Crpt PF13342.6 GAK62365.1 - 0.43 10.6 2.8 6.3 6.8 0.3 2.5 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase Chorismate_bind PF00425.18 GAK62366.1 - 1.6e-86 290.1 0.0 2.2e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 GAK62366.1 - 9.9e-27 93.9 0.0 3.2e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Pox_A12 PF04651.13 GAK62366.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A12 protein DUF2685 PF10886.8 GAK62366.1 - 0.16 12.1 0.1 23 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) PIG-L PF02585.17 GAK62368.1 - 5.8e-22 78.7 0.3 8.1e-22 78.3 0.3 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Met_10 PF02475.16 GAK62369.1 - 3.6e-54 183.5 0.0 6.7e-47 159.8 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein T3SS_NleG PF06416.12 GAK62369.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Effector protein NleG Fungal_trans PF04082.18 GAK62370.1 - 9.5e-09 34.7 0.1 1.9e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62370.1 - 4.5e-06 26.7 9.2 8.5e-06 25.8 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PalH PF08733.10 GAK62371.1 - 0.42 9.6 2.7 1.1 8.2 2.7 1.6 1 1 0 1 1 1 0 PalH/RIM21 UCH PF00443.29 GAK62372.1 - 1e-38 133.3 0.0 1.5e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAK62372.1 - 3.5e-25 88.1 7.4 5.7e-19 68.2 1.7 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GAK62372.1 - 5.4e-24 83.7 3.2 5.3e-23 80.5 0.2 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 GAK62372.1 - 6.8e-20 70.6 0.6 6.6e-09 35.5 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 GAK62372.1 - 1.6e-11 44.4 0.0 1.1e-10 41.6 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 GAK62372.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Pex2_Pex12 PF04757.14 GAK62373.1 - 1.7e-43 148.8 0.4 2.1e-43 148.5 0.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 GAK62373.1 - 8.5e-05 22.3 0.8 0.00013 21.8 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAK62373.1 - 0.0013 19.0 1.0 0.0024 18.2 1.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAK62373.1 - 0.0016 18.3 2.0 0.003 17.4 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK62373.1 - 0.013 15.4 0.9 0.021 14.7 0.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK62373.1 - 0.11 12.6 3.4 0.19 11.8 3.4 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAK62373.1 - 0.14 12.4 4.2 0.24 11.6 4.2 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAK62373.1 - 0.33 10.8 3.1 3.3 7.6 3.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAK62374.1 - 0.00033 20.5 6.8 0.00054 19.8 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK62374.1 - 0.067 13.1 11.1 0.1 12.5 11.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Paf1 PF03985.13 GAK62374.1 - 4.3 6.2 5.3 6.2 5.7 5.3 1.1 1 0 0 1 1 1 0 Paf1 Rtf2 PF04641.12 GAK62374.1 - 9.8 5.5 7.3 17 4.7 7.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Ras PF00071.22 GAK62375.1 - 2.5e-52 176.7 0.0 3.2e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK62375.1 - 2.5e-18 66.4 0.0 3.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK62375.1 - 4.4e-06 26.3 0.0 7.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Peptidase_S28 PF05577.12 GAK62376.1 - 6.5e-39 133.9 0.0 8.3e-35 120.4 0.0 2.6 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Brix PF04427.18 GAK62377.1 - 8.5e-43 146.7 0.0 1.4e-42 146.0 0.0 1.4 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 GAK62377.1 - 0.00042 20.4 3.8 0.00063 19.9 3.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 GAK62377.1 - 0.73 9.5 17.0 1.4 8.6 17.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GAK62377.1 - 3.2 7.0 17.7 5 6.4 17.7 1.3 1 0 0 1 1 1 0 BUD22 NUP50 PF08911.11 GAK62377.1 - 3.8 8.2 9.5 1.1 9.9 0.2 3.1 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) NOA36 PF06524.12 GAK62377.1 - 4.5 6.5 15.7 6.8 5.9 15.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GAK62377.1 - 7.1 4.7 22.7 9.6 4.3 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 GAK62378.1 - 1.8e-12 47.6 7.6 0.03 15.2 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 GAK62378.1 - 0.15 10.7 2.9 7.7 5.0 0.4 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 CLTH PF10607.9 GAK62379.1 - 2.2e-18 66.6 0.0 3.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAK62379.1 - 0.0045 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 LisH DUF3194 PF11419.8 GAK62379.1 - 0.044 14.1 0.2 0.26 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3194) PTCB-BRCT PF12738.7 GAK62380.1 - 1.9e-33 114.2 0.0 1.1e-11 44.5 0.0 4.6 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 GAK62380.1 - 5.5e-30 103.6 0.0 5.6e-10 39.5 0.0 5.4 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain CENP-C_C PF11699.8 GAK62380.1 - 6e-29 100.1 0.0 1.1e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like BRCT_2 PF16589.5 GAK62380.1 - 1.6e-11 44.5 0.0 0.21 12.0 0.0 5.4 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GAK62380.1 - 2.8e-06 27.5 0.0 0.27 11.6 0.0 4.9 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 GAK62380.1 - 0.0077 16.1 0.0 0.63 9.9 0.0 2.9 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain Cupin_2 PF07883.11 GAK62380.1 - 0.009 15.7 0.0 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 Cupin domain tRNA_Me_trans PF03054.16 GAK62381.1 - 1.9e-105 352.6 0.0 3.3e-105 351.8 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 GAK62381.1 - 0.0025 17.0 0.1 0.24 10.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 GAK62381.1 - 0.1 12.1 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Tom37 PF10568.9 GAK62382.1 - 3.4e-16 59.7 0.1 7e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 GAK62382.1 - 4.9e-06 26.2 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pox_Ag35 PF03286.14 GAK62382.1 - 0.16 11.7 2.1 0.27 11.0 2.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIA PF03153.13 GAK62382.1 - 0.51 10.3 11.2 0.76 9.7 11.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 GAK62382.1 - 5.5 6.3 16.5 7.6 5.9 16.5 1.2 1 0 0 1 1 1 0 SDA1 Lactonase PF10282.9 GAK62383.1 - 1.5e-14 54.1 0.7 2.4e-13 50.0 0.2 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller AMP-binding PF00501.28 GAK62387.1 - 6e-42 143.7 0.0 8.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAK62387.1 - 2.2e-07 30.7 0.0 4.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Synaptobrevin PF00957.21 GAK62388.1 - 2.8e-24 84.7 0.1 4e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAK62388.1 - 1e-18 67.1 0.0 2.8e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain ApbA_C PF08546.11 GAK62389.1 - 6.4e-27 94.2 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAK62389.1 - 7.8e-21 74.3 0.0 1.5e-20 73.4 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Sec63 PF02889.16 GAK62390.1 - 5.3e-72 242.1 0.0 8e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 GAK62390.1 - 2.5e-36 125.1 0.2 2.4e-27 95.8 0.2 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 GAK62390.1 - 1e-14 54.9 0.0 3e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAK62390.1 - 2.1e-07 31.3 0.1 0.00017 21.9 0.0 4.5 4 1 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAK62390.1 - 1.9e-05 25.0 0.6 0.052 13.8 0.2 3.5 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAK62390.1 - 4.8e-05 22.6 0.2 0.064 12.3 0.0 3.9 4 0 0 4 4 4 1 Type II/IV secretion system protein Helicase_PWI PF18149.1 GAK62390.1 - 0.00028 21.0 0.0 0.0012 19.0 0.0 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_7 PF12775.7 GAK62390.1 - 0.0012 18.3 0.1 0.13 11.7 0.1 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAK62390.1 - 0.0018 18.0 0.3 2.1 8.0 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_29 PF13555.6 GAK62390.1 - 0.0087 15.8 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK62390.1 - 0.025 14.9 0.1 0.025 14.9 0.1 5.1 6 1 0 6 6 6 0 AAA ATPase domain Homeodomain PF00046.29 GAK62391.1 - 2.2e-12 46.6 1.1 6.9e-12 45.0 1.1 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAK62391.1 - 0.0043 16.9 0.0 0.018 15.0 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain Peptidase_M28 PF04389.17 GAK62392.1 - 8.9e-36 123.4 0.4 1.5e-35 122.7 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M28 GATase_4 PF13230.6 GAK62392.1 - 0.074 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II NPR2 PF06218.11 GAK62393.1 - 2.3e-91 306.8 0.5 9.2e-40 136.7 0.0 5.3 3 2 1 4 4 4 4 Nitrogen permease regulator 2 Acetyltransf_1 PF00583.25 GAK62393.1 - 3.1e-10 40.3 0.0 6.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HhH-GPD PF00730.25 GAK62393.1 - 6.6e-10 39.4 0.0 1.7e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Acetyltransf_10 PF13673.7 GAK62393.1 - 9.8e-05 22.3 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK62393.1 - 0.00055 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GAK62393.1 - 0.001 19.4 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF908 PF06012.12 GAK62394.1 - 0.0045 16.5 7.9 0.006 16.0 7.9 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Collectrin PF16959.5 GAK62394.1 - 0.015 15.1 0.3 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 Renal amino acid transporter Mucin PF01456.17 GAK62394.1 - 0.076 13.0 17.6 0.16 12.0 17.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MSP1_C PF07462.11 GAK62394.1 - 0.37 9.4 2.1 0.51 9.0 2.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Plasmodium_Vir PF05795.11 GAK62394.1 - 3.3 7.0 5.2 5.3 6.3 5.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ATF7IP_BD PF16788.5 GAK62394.1 - 5.6 7.0 9.7 8.1 6.5 9.7 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain Rhodanese PF00581.20 GAK62395.1 - 1.2e-10 41.9 0.0 2.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.13 GAK62396.1 - 6.6e-247 821.5 14.7 6.6e-247 821.5 14.7 1.6 2 0 0 2 2 2 1 DNA polymerase phi Creb_binding PF09030.10 GAK62396.1 - 0.18 12.5 2.1 20 5.9 0.0 3.8 3 0 0 3 3 3 0 Creb binding DUF2786 PF10979.8 GAK62396.1 - 1.9 8.5 5.0 1.1 9.2 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Pkinase PF00069.25 GAK62397.1 - 3.1e-26 92.3 0.0 4.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62397.1 - 3.3e-13 49.5 0.0 5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK62397.1 - 7.5e-08 31.6 2.1 2.9e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Presenilin PF01080.17 GAK62397.1 - 0.53 9.0 5.2 0.8 8.4 5.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 GAK62397.1 - 2.6 7.3 7.0 3.7 6.8 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coa1 PF08695.10 GAK62398.1 - 9.9e-27 93.0 0.1 1.2e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SNARE_assoc PF09335.11 GAK62399.1 - 9.1e-18 64.9 12.2 2.9e-17 63.3 9.4 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Saf_2TM PF18303.1 GAK62399.1 - 0.034 13.7 0.7 0.034 13.7 0.7 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF4692 PF15763.5 GAK62399.1 - 0.06 13.8 1.0 0.19 12.2 1.0 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Lipase_3 PF01764.25 GAK62400.1 - 1.2e-07 31.6 0.0 3.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAK62400.1 - 0.02 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK62400.1 - 2.6 8.6 8.0 0.21 12.2 1.1 2.6 2 2 0 2 2 2 0 Alpha/beta hydrolase family VEFS-Box PF09733.9 GAK62401.1 - 0.32 10.8 3.7 0.72 9.7 3.7 1.5 1 0 0 1 1 1 0 VEFS-Box of polycomb protein RRM_1 PF00076.22 GAK62402.1 - 2.9e-23 81.5 0.0 2.1e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 GAK62402.1 - 1.4e-21 74.9 0.0 0.00043 19.8 0.0 6.6 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 GAK62402.1 - 0.00013 21.7 0.0 0.35 10.8 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_8 PF11835.8 GAK62402.1 - 0.0029 17.8 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 RRM-like domain DUF4523 PF15023.6 GAK62402.1 - 0.23 11.3 0.0 9.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) 2OG-FeII_Oxy_2 PF13532.6 GAK62403.1 - 1.4e-13 51.5 0.1 3.5e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily IER PF05760.12 GAK62404.1 - 5.6 7.2 5.8 29 4.8 0.0 2.5 2 1 0 2 2 2 0 Immediate early response protein (IER) adh_short PF00106.25 GAK62405.1 - 3.4e-18 65.8 1.0 2.4e-13 50.0 0.1 3.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK62405.1 - 2.1e-11 43.8 8.5 7.2e-07 29.0 2.5 3.8 2 2 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK62405.1 - 2.1e-05 24.5 5.8 0.0011 19.0 0.6 2.6 1 1 1 2 2 2 2 KR domain RNA_polI_A34 PF08208.11 GAK62406.1 - 1.2e-11 45.1 6.1 1.2e-11 45.1 6.1 2.4 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Biotin_lipoyl PF00364.22 GAK62407.1 - 2e-21 75.6 2.7 4.3e-21 74.5 2.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAK62407.1 - 2.2e-08 34.3 0.0 6.6e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAK62407.1 - 3.3e-06 26.8 0.2 9.9e-05 22.1 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like Med25_NR-box PF11244.8 GAK62407.1 - 0.013 15.9 0.3 0.031 14.7 0.3 1.7 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing HlyD_D23 PF16576.5 GAK62407.1 - 0.13 11.5 1.5 5.5 6.2 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion zf-C2H2 PF00096.26 GAK62408.1 - 8.9e-23 79.4 44.7 5.6e-06 26.5 0.3 9.2 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK62408.1 - 1e-17 63.6 50.2 5e-08 33.0 3.3 7.8 9 0 0 9 9 9 4 Zinc-finger double domain FOXP-CC PF16159.5 GAK62408.1 - 4.2e-10 40.1 32.9 0.0016 19.0 1.1 7.4 4 1 3 7 7 7 3 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAK62408.1 - 9.8e-08 32.2 68.9 5.2e-05 23.7 0.6 10.0 11 0 0 11 11 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAK62408.1 - 9.3e-06 25.8 11.1 0.0019 18.5 0.1 4.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 GAK62408.1 - 0.00055 19.6 11.7 0.29 11.0 0.5 5.1 4 0 0 4 4 4 2 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 GAK62408.1 - 0.0021 18.5 1.3 0.11 12.9 0.0 4.0 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 GAK62408.1 - 0.0047 17.3 5.2 0.17 12.3 0.4 3.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 GAK62408.1 - 0.044 13.6 0.4 0.044 13.6 0.4 5.8 6 0 0 6 6 5 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 GAK62408.1 - 0.052 13.6 0.7 0.052 13.6 0.7 6.5 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAK62408.1 - 0.1 12.7 7.0 7.2 6.7 0.2 4.1 2 1 1 4 4 4 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 GAK62408.1 - 0.31 11.4 15.3 0.063 13.6 1.2 4.5 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 GAK62408.1 - 1.5 8.5 13.4 4.1 7.1 1.0 4.8 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger DUF498 PF04430.14 GAK62409.1 - 5.3e-27 94.0 0.0 7.6e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Amino_oxidase PF01593.24 GAK62409.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Mito_carr PF00153.27 GAK62410.1 - 1.3e-41 140.5 3.8 1.8e-14 53.4 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein GCV_H PF01597.19 GAK62412.1 - 8.1e-44 148.4 0.1 9.5e-44 148.2 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 GAK62412.1 - 8.3e-05 22.5 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 GAK62412.1 - 9.1e-05 22.2 0.2 0.00016 21.4 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAK62412.1 - 0.04 13.8 1.0 5.2 7.0 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Radical_SAM_C PF16199.5 GAK62413.1 - 1.2e-31 108.6 0.1 3.3e-31 107.1 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 GAK62413.1 - 5.4e-18 65.9 0.1 2e-17 64.1 0.1 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 GAK62413.1 - 5.4e-08 33.1 0.1 1.1e-07 32.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAK62413.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK62413.1 - 0.0049 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK62413.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RINGv PF12906.7 GAK62414.1 - 4.7e-13 49.0 4.5 7.3e-13 48.4 4.5 1.3 1 0 0 1 1 1 1 RING-variant domain DUF983 PF06170.12 GAK62414.1 - 0.013 15.9 1.5 1.1 9.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-RING_2 PF13639.6 GAK62414.1 - 0.16 12.3 2.0 0.26 11.6 2.0 1.4 1 0 0 1 1 1 0 Ring finger domain Fasciclin PF02469.22 GAK62415.1 - 5.1e-56 188.4 0.2 9.9e-13 48.4 0.0 7.0 7 1 0 7 7 7 6 Fasciclin domain DUF4381 PF14316.6 GAK62415.1 - 0.55 10.5 3.9 1.1 9.5 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) adh_short PF00106.25 GAK62416.1 - 2.3e-44 151.2 0.0 2.7e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK62416.1 - 1.7e-34 119.4 0.0 2.2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK62416.1 - 2.4e-11 43.9 0.0 4.3e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAK62416.1 - 2.4e-05 23.9 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAK62416.1 - 5.4e-05 22.8 0.1 0.00023 20.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAK62416.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 GAK62416.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAK62416.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GAS2 PF02187.17 GAK62417.1 - 2.1e-12 46.9 0.0 4.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SPACA9 PF15120.6 GAK62417.1 - 0.14 12.0 0.6 0.28 11.0 0.6 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 RRM_1 PF00076.22 GAK62418.1 - 1.5e-11 44.0 0.0 1.5e-10 40.7 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK62418.1 - 0.006 16.2 0.0 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.20 GAK62419.1 - 5.7e-07 29.4 0.3 5.7e-07 29.4 0.3 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK62419.1 - 4.5e-06 26.1 0.1 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GAK62419.1 - 0.046 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SOG2 PF10428.9 GAK62420.1 - 0.068 12.4 16.4 0.1 11.8 16.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PA26 PF04636.13 GAK62420.1 - 0.33 9.8 1.7 0.43 9.5 1.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 GAK62420.1 - 0.46 9.7 4.2 0.74 9.0 4.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 GAK62420.1 - 0.56 10.2 1.9 0.77 9.8 1.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 GAK62420.1 - 3.2 6.8 11.1 4.6 6.2 11.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Utp14 PF04615.13 GAK62420.1 - 3.3 6.2 28.5 4.4 5.8 28.5 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2457 PF10446.9 GAK62420.1 - 6.9 5.7 16.4 10 5.1 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LAP1C PF05609.12 GAK62420.1 - 7.2 5.6 18.0 10 5.1 18.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PI3K_1B_p101 PF10486.9 GAK62420.1 - 7.5 4.2 11.2 8.9 3.9 11.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Glyco_hydro_5_C PF18564.1 GAK62421.1 - 2.7e-10 40.6 0.1 2.2e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 GAK62421.1 - 2.4e-08 33.8 0.0 8.5e-06 25.4 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Ndc80_HEC PF03801.13 GAK62422.1 - 4.3e-31 107.6 0.0 1.9e-29 102.3 0.0 2.4 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 GAK62422.1 - 5.9e-20 71.1 1.2 5.9e-20 71.1 1.2 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF5595) DUF2031 PF09592.10 GAK62422.1 - 0.058 12.9 8.5 0.12 11.9 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Lzipper-MIP1 PF14389.6 GAK62422.1 - 0.65 10.3 10.4 0.078 13.3 3.5 3.0 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 SLATT_4 PF18186.1 GAK62422.1 - 3.9 7.1 9.6 1.7 8.3 5.7 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 GAS PF13851.6 GAK62422.1 - 6.9 6.0 41.1 8 5.8 17.0 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CAP_N PF01213.19 GAK62423.1 - 1.9e-116 389.0 6.5 1.9e-116 389.0 6.5 1.7 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GAK62423.1 - 8.6e-61 204.1 1.9 1.2e-60 203.7 1.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal F-box-like PF12937.7 GAK62423.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 F-box-like TBCC PF07986.12 GAK62423.1 - 0.0059 16.3 2.8 0.012 15.4 2.8 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Ribosomal_60s PF00428.19 GAK62424.1 - 2.3e-24 85.8 11.2 2.3e-24 85.8 11.2 2.3 2 1 0 2 2 2 1 60s Acidic ribosomal protein ACP PF06857.11 GAK62424.1 - 0.013 15.7 0.5 0.05 13.8 0.2 1.9 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) Etmic-2 PF06670.11 GAK62424.1 - 0.28 10.1 7.2 0.042 12.8 3.4 1.4 1 1 0 1 1 1 0 Microneme protein Etmic-2 Mito_carr PF00153.27 GAK62425.1 - 5.1e-52 173.8 0.9 2.4e-18 65.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF_assoc_1 PF08355.12 GAK62427.1 - 0.00039 19.9 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_4 PF12763.7 GAK62427.1 - 0.05 13.6 0.0 0.22 11.5 0.0 2.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand OST-HTH PF12872.7 GAK62427.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 OST-HTH/LOTUS domain DEAD PF00270.29 GAK62428.1 - 1.6e-31 109.4 0.0 2.8e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK62428.1 - 9.5e-30 103.2 0.1 8.2e-29 100.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK62428.1 - 0.0022 18.0 0.0 0.0073 16.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 GAK62428.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.6 GAK62428.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ANAPC4_WD40 PF12894.7 GAK62429.1 - 1.5e-07 31.6 0.1 0.011 16.0 0.0 5.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAK62429.1 - 7.8e-07 29.7 14.3 0.89 10.5 0.1 8.3 8 1 0 8 8 8 3 WD domain, G-beta repeat PQQ_3 PF13570.6 GAK62429.1 - 0.0024 18.3 0.9 0.19 12.3 0.1 4.3 4 0 0 4 4 4 1 PQQ-like domain CENP-B_dimeris PF09026.10 GAK62429.1 - 0.0096 16.3 4.6 0.026 14.9 4.6 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GAK62429.1 - 4.6 5.2 7.5 6.6 4.7 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 GAK62429.1 - 9.1 6.7 10.6 23 5.4 10.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S6 PF01250.17 GAK62430.1 - 1.3e-23 83.0 0.0 1.6e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Response_reg PF00072.24 GAK62431.1 - 9.9e-21 74.0 0.1 2.1e-15 56.9 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain ISG65-75 PF11727.8 GAK62434.1 - 0.0066 15.7 4.6 0.018 14.3 4.6 1.7 1 0 0 1 1 1 1 Invariant surface glycoprotein DivIVA PF05103.13 GAK62434.1 - 0.93 9.6 19.5 0.58 10.3 12.2 2.9 2 1 1 3 3 3 0 DivIVA protein Tup_N PF08581.10 GAK62434.1 - 3.8 7.9 12.9 0.37 11.1 2.2 3.2 3 0 0 3 3 3 0 Tup N-terminal Nup88 PF10168.9 GAK62434.1 - 5.4 4.7 14.3 10 3.8 14.3 1.3 1 0 0 1 1 1 0 Nuclear pore component UPF1_Zn_bind PF09416.10 GAK62435.1 - 2.1e-70 235.6 6.3 2.1e-70 235.6 6.3 1.8 2 0 0 2 2 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GAK62435.1 - 1.2e-58 198.1 0.0 2.2e-58 197.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAK62435.1 - 6.4e-50 170.4 3.3 9e-29 101.0 0.4 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 GAK62435.1 - 1.4e-32 111.8 0.0 3.2e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GAK62435.1 - 6.8e-14 52.0 0.0 3.2e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK62435.1 - 1.2e-10 41.9 0.0 4.8e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 GAK62435.1 - 4.8e-05 23.4 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 GAK62435.1 - 0.00014 21.7 0.2 1 9.0 0.0 3.2 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 GAK62435.1 - 0.00088 18.6 0.4 0.0096 15.2 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 GAK62435.1 - 0.0017 18.3 0.0 0.0035 17.2 0.0 1.6 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 GAK62435.1 - 0.003 17.1 0.0 0.0093 15.5 0.0 1.7 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 GAK62435.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 GAK62435.1 - 0.042 13.5 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 GAK62435.1 - 0.054 12.6 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 GAK62435.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAK62435.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 GAK62435.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 GAK62435.1 - 0.24 10.9 0.2 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Cellulase PF00150.18 GAK62436.1 - 7.4e-18 65.0 0.1 7.4e-18 65.0 0.1 1.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SYF2 PF08231.12 GAK62437.1 - 1.7e-46 158.5 19.5 3.3e-46 157.6 19.5 1.4 1 0 0 1 1 1 1 SYF2 splicing factor Smg4_UPF3 PF03467.15 GAK62438.1 - 2.2e-58 197.1 0.1 2.2e-58 197.1 0.1 3.3 4 0 0 4 4 4 1 Smg-4/UPF3 family Gtr1_RagA PF04670.12 GAK62439.1 - 1.3e-86 289.7 0.0 1.8e-86 289.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 GAK62439.1 - 6.6e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAK62439.1 - 9.3e-06 25.7 0.0 2.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 GAK62439.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK62439.1 - 0.00031 20.3 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAK62439.1 - 0.0048 16.1 0.2 1.4 8.0 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 GAK62439.1 - 0.01 16.2 0.3 0.022 15.1 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAK62439.1 - 0.023 14.6 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 GAK62439.1 - 0.028 13.9 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAK62439.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.18 GAK62439.1 - 0.045 13.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 GAK62439.1 - 0.052 14.1 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mobilization_B PF17511.2 GAK62439.1 - 0.053 13.9 0.7 0.11 12.9 0.7 1.4 1 0 0 1 1 1 0 Mobilization protein B PduV-EutP PF10662.9 GAK62439.1 - 0.073 12.8 0.5 0.17 11.6 0.2 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Formyl_trans_N PF00551.19 GAK62440.1 - 2.8e-38 131.5 0.0 3.9e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 GAK62440.1 - 2.5e-06 27.1 0.0 7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 GAK62440.1 - 2.1e-05 24.4 0.0 8.2e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 ACT domain FMO-like PF00743.19 GAK62441.1 - 9.3e-23 80.4 0.0 6.7e-13 47.9 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 GAK62441.1 - 6.7e-09 35.9 0.1 1.8e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAK62441.1 - 9.8e-09 34.9 0.0 1.2e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK62441.1 - 1.8e-08 34.4 2.4 2.2e-08 34.2 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAK62441.1 - 4.5e-08 32.7 0.1 0.0019 17.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK62441.1 - 6.7e-05 22.6 0.2 0.0016 18.1 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAK62441.1 - 7.4e-05 22.0 0.0 0.064 12.4 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAK62441.1 - 0.0028 18.2 0.1 0.029 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK62441.1 - 0.0032 16.8 0.1 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAK62441.1 - 0.0047 15.7 0.1 0.0069 15.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 GAK62441.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAK62441.1 - 0.021 14.1 0.2 0.11 11.7 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 GAK62441.1 - 0.036 13.4 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Tis11B_N PF04553.12 GAK62443.1 - 0.21 12.1 5.2 0.17 12.4 0.7 2.3 2 0 0 2 2 2 0 Tis11B like protein, N terminus E1-E2_ATPase PF00122.20 GAK62444.1 - 1e-45 155.5 3.0 1e-45 155.5 3.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAK62444.1 - 2.5e-35 122.7 1.5 5e-35 121.7 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAK62444.1 - 1.3e-31 108.9 0.2 8.6e-16 58.1 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.7 GAK62444.1 - 4.6e-05 23.9 0.1 0.00027 21.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAK62444.1 - 0.00014 21.7 0.5 0.0096 15.7 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAK62444.1 - 0.0091 16.1 0.0 0.077 13.1 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase TGS PF02824.21 GAK62444.1 - 0.11 12.6 0.0 0.49 10.5 0.0 2.1 1 0 0 1 1 1 0 TGS domain AbiEi_2 PF09952.9 GAK62444.1 - 0.13 12.5 0.0 11 6.2 0.0 3.2 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system HAD_2 PF13419.6 GAK62444.1 - 0.17 11.9 0.0 0.6 10.2 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1325 PF07039.11 GAK62445.1 - 1.5e-27 96.3 0.0 2.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4889 PF16230.5 GAK62445.1 - 0.19 12.0 0.1 0.45 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) FMN_bind_2 PF04299.12 GAK62447.1 - 4e-52 176.3 0.2 4.8e-52 176.1 0.2 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain MIP PF00230.20 GAK62448.1 - 8.8e-51 172.8 17.0 1.2e-50 172.3 17.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4271 PF14093.6 GAK62448.1 - 0.034 14.1 0.2 0.034 14.1 0.2 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) Phage_holin_5_2 PF16079.5 GAK62448.1 - 1 9.7 6.3 2.9 8.3 0.0 3.2 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V MFS_1 PF07690.16 GAK62450.1 - 2.6e-20 72.6 66.8 7.5e-12 44.8 29.5 3.6 2 2 1 3 3 3 2 Major Facilitator Superfamily Tetraspanin PF00335.20 GAK62450.1 - 0.00046 20.0 6.2 0.00046 20.0 6.2 2.8 2 0 0 2 2 2 1 Tetraspanin family MgtE PF01769.16 GAK62451.1 - 3.5e-40 137.2 35.3 4e-24 85.4 8.9 4.4 2 1 1 3 3 3 2 Divalent cation transporter WD40 PF00400.32 GAK62452.1 - 3.8e-39 132.0 21.4 4e-07 30.6 0.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK62452.1 - 7.7e-20 71.0 1.0 0.0045 17.3 0.1 5.9 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAK62452.1 - 1.6e-07 31.4 0.1 0.013 15.4 0.0 3.8 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAK62452.1 - 8.1e-07 28.3 0.0 0.0031 16.5 0.0 2.9 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 GAK62452.1 - 0.011 15.7 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region BDV_G PF06208.11 GAK62452.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus G protein Frtz PF11768.8 GAK62452.1 - 0.16 10.3 0.0 3.9 5.7 0.0 2.6 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz CAF1A PF12253.8 GAK62453.1 - 9.2e-22 77.0 5.5 9.2e-22 77.0 5.5 3.1 2 2 1 3 3 3 1 Chromatin assembly factor 1 subunit A EMC3_TMCO1 PF01956.16 GAK62453.1 - 5.4 6.7 6.3 13 5.5 6.3 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like AAA PF00004.29 GAK62454.1 - 2.5e-17 63.5 0.0 8.7e-17 61.8 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAK62454.1 - 1.3e-13 51.0 0.0 1.7e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 GAK62454.1 - 4.6e-12 46.2 0.1 1.4e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 GAK62454.1 - 3.3e-07 30.4 0.1 1.7e-06 28.1 0.1 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GAK62454.1 - 2.5e-06 27.8 1.1 0.0064 16.8 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 GAK62454.1 - 1.6e-05 25.3 0.0 0.0011 19.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 GAK62454.1 - 4.9e-05 23.2 0.9 0.00012 21.9 0.0 2.0 1 1 2 3 3 3 1 AAA domain AAA_14 PF13173.6 GAK62454.1 - 0.00012 22.1 0.0 0.0011 19.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 GAK62454.1 - 0.00015 21.6 0.1 0.00044 20.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 GAK62454.1 - 0.00042 20.6 0.0 0.0015 18.9 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 GAK62454.1 - 0.00055 19.9 0.0 0.002 18.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAK62454.1 - 0.00093 18.6 0.1 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GAK62454.1 - 0.00099 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAK62454.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 GAK62454.1 - 0.0011 18.7 0.0 0.0058 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GAK62454.1 - 0.0024 17.9 0.0 0.034 14.1 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAK62454.1 - 0.0027 18.1 0.2 0.013 15.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 GAK62454.1 - 0.0044 16.8 0.1 0.058 13.2 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.6 GAK62454.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAK62454.1 - 0.019 14.9 0.1 0.071 13.0 0.0 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GAK62454.1 - 0.02 14.0 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.23 GAK62454.1 - 0.033 13.3 0.0 0.12 11.4 0.0 1.9 1 1 0 1 1 1 0 MCM P-loop domain Parvo_NS1 PF01057.17 GAK62454.1 - 0.038 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 GAK62454.1 - 0.042 14.0 0.0 0.2 11.8 0.0 2.1 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAK62454.1 - 0.05 14.2 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAK62454.1 - 0.069 12.4 0.0 0.29 10.3 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 GAK62454.1 - 0.11 12.5 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 GAK62454.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF241 PF03087.14 GAK62454.1 - 3 7.6 5.7 20 4.9 0.1 2.3 2 0 0 2 2 2 0 Arabidopsis protein of unknown function AA_kinase PF00696.28 GAK62455.1 - 8.6e-42 143.4 0.8 1.2e-41 142.9 0.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 GAK62455.1 - 1.9e-10 40.6 0.0 7.2e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 PUA domain Aldedh PF00171.22 GAK62456.1 - 8.9e-127 423.4 0.1 1.1e-126 423.1 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAK62456.1 - 0.01 14.9 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Flagellin_IN PF07196.13 GAK62456.1 - 0.091 13.0 0.3 0.41 10.9 0.3 2.2 1 0 0 1 1 1 0 Flagellin hook IN motif Gpi1 PF05024.15 GAK62457.1 - 7.5e-56 189.2 5.4 1.1e-55 188.6 5.4 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Vac_ImportDeg PF09783.9 GAK62458.1 - 1.2e-54 184.5 0.0 4.2e-49 166.5 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein Spc24 PF08286.11 GAK62459.1 - 4.6e-08 33.2 19.4 5.1e-07 29.9 9.5 3.4 2 2 0 2 2 2 1 Spc24 subunit of Ndc80 Spectrin_like PF18373.1 GAK62459.1 - 0.011 15.7 2.2 0.011 15.7 2.2 2.4 2 1 0 2 2 2 0 Spectrin like domain Filament PF00038.21 GAK62459.1 - 0.013 15.1 16.3 0.24 10.9 16.4 2.0 1 1 0 1 1 1 0 Intermediate filament protein Rootletin PF15035.6 GAK62459.1 - 0.03 14.3 13.8 0.1 12.6 0.5 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Sec2p PF06428.11 GAK62459.1 - 0.12 12.4 13.5 0.43 10.6 11.5 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FliD_N PF02465.18 GAK62459.1 - 0.13 13.0 9.4 2.7 8.8 2.4 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4872 PF16169.5 GAK62459.1 - 0.61 9.8 6.1 0.32 10.7 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4872) TMF_DNA_bd PF12329.8 GAK62459.1 - 0.86 9.6 17.5 0.094 12.7 7.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 GAK62459.1 - 1.7 6.5 8.2 1.9 6.3 8.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 GAK62459.1 - 3.4 8.1 6.8 7.1 7.1 2.1 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SLX9 PF15341.6 GAK62459.1 - 3.5 8.0 13.8 15 6.0 13.7 1.9 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 MutS_III PF05192.18 GAK62459.1 - 3.6 7.8 11.9 18 5.5 11.4 1.9 1 1 0 1 1 1 0 MutS domain III TMCO5 PF14992.6 GAK62459.1 - 4.7 6.7 16.6 0.72 9.4 8.4 2.1 1 1 1 2 2 2 0 TMCO5 family Fib_alpha PF08702.10 GAK62459.1 - 7.2 6.8 7.8 27 4.9 7.5 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 GAK62459.1 - 7.6 5.0 8.9 12 4.3 8.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF5476 PF17570.2 GAK62461.1 - 0.18 12.2 1.4 1.2 9.6 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5476) FAD_binding_3 PF01494.19 GAK62462.1 - 2.8e-26 92.6 0.0 4.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAK62462.1 - 7.5e-12 45.1 0.1 1.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK62462.1 - 3.7e-11 43.2 0.4 0.00022 20.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAK62462.1 - 2.7e-09 37.4 0.1 2e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK62462.1 - 2.9e-05 24.2 0.0 0.0001 22.4 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAK62462.1 - 0.00016 20.5 0.0 0.077 11.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 GAK62462.1 - 0.00059 19.3 0.2 0.001 18.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase CoA_transf_3 PF02515.17 GAK62462.1 - 0.00074 18.7 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III FAD_binding_2 PF00890.24 GAK62462.1 - 0.00088 18.5 0.2 0.0056 15.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 GAK62462.1 - 0.0022 16.9 1.2 0.17 10.7 0.1 2.4 1 1 1 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 GAK62462.1 - 0.0061 15.9 0.1 0.0091 15.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 GAK62462.1 - 0.0064 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 GAK62462.1 - 0.017 14.4 0.1 0.81 8.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 GAK62462.1 - 0.041 13.8 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 GAK62462.1 - 0.041 13.0 0.1 0.067 12.3 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAK62462.1 - 0.076 12.0 0.2 0.35 9.9 0.2 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 GAK62462.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UL20 PF17582.2 GAK62463.1 - 0.23 10.7 0.2 0.3 10.3 0.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL20 MSC PF09402.10 GAK62464.1 - 1.1e-92 311.1 0.7 1.5e-92 310.7 0.7 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 GAK62464.1 - 3.5e-14 52.2 0.0 1e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 HeH/LEM domain Mito_carr PF00153.27 GAK62465.1 - 8.3e-62 205.2 5.3 4.1e-22 77.9 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 GAK62465.1 - 0.056 12.6 2.5 0.25 10.5 0.0 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Sugar_tr PF00083.24 GAK62466.1 - 5.7e-20 71.6 4.9 5.7e-20 71.6 4.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAK62466.1 - 5.8e-20 71.5 58.6 2.3e-14 53.1 29.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HSP9_HSP12 PF04119.12 GAK62467.1 - 1.6e-23 82.9 14.1 1.5e-19 70.2 5.7 2.2 1 1 2 3 3 3 2 Heat shock protein 9/12 MT0933_antitox PF14013.6 GAK62467.1 - 0.68 10.3 10.2 4e+02 1.4 10.2 2.5 1 1 0 1 1 1 0 MT0933-like antitoxin protein E1-E2_ATPase PF00122.20 GAK62468.1 - 1.2e-42 145.5 2.1 1.2e-42 145.5 2.1 3.9 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAK62468.1 - 1.2e-31 109.9 4.0 1.2e-31 109.9 4.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAK62468.1 - 9.7e-19 68.5 2.1 6.2e-18 65.9 2.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAK62468.1 - 4.3e-18 65.2 0.0 1.1e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAK62468.1 - 4e-17 61.7 0.1 4e-17 61.7 0.1 3.5 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAK62468.1 - 0.0026 17.5 0.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.22 GAK62470.1 - 5.3e-55 187.0 0.0 1.1e-54 186.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 VASP_tetra PF08776.11 GAK62470.1 - 0.15 11.7 2.2 0.35 10.5 2.2 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain Pro_CA PF00484.19 GAK62471.1 - 1.9e-37 129.0 0.3 5.5e-37 127.5 0.2 1.8 2 0 0 2 2 2 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 GAK62471.1 - 0.0084 15.8 0.0 0.027 14.1 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Gemini_C4 PF01492.17 GAK62471.1 - 0.013 15.4 0.9 0.024 14.6 0.9 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein DUF4203 PF13886.6 GAK62472.1 - 5.4e-49 166.6 24.0 7.7e-49 166.1 24.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) FA_desaturase PF00487.24 GAK62472.1 - 0.75 9.6 4.3 1.7 8.4 4.3 1.6 1 0 0 1 1 1 0 Fatty acid desaturase JAB PF01398.21 GAK62474.1 - 1.4e-05 25.1 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ribosomal_L31e PF01198.19 GAK62475.1 - 2.7e-38 130.0 0.9 5.2e-38 129.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e Methyltransf_33 PF10017.9 GAK62476.1 - 9.8e-81 271.3 0.0 5.3e-66 222.9 0.0 2.2 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 GAK62476.1 - 2.1e-22 80.0 1.2 8e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 dCMP_cyt_deam_1 PF00383.23 GAK62476.1 - 2.4e-21 75.5 0.0 4.2e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAK62476.1 - 6.8e-19 68.0 0.0 4.8e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAK62476.1 - 0.00012 22.1 0.0 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase DinB_2 PF12867.7 GAK62476.1 - 0.0037 17.8 0.9 0.016 15.7 0.9 2.2 1 0 0 1 1 1 1 DinB superfamily Gpr1_Fun34_YaaH PF01184.19 GAK62478.1 - 1.7e-86 289.1 20.6 2.1e-86 288.8 20.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Transglycosylas PF06737.14 GAK62478.1 - 0.53 11.0 5.6 4.7 7.9 0.3 3.1 3 0 0 3 3 3 0 Transglycosylase-like domain Zn_clus PF00172.18 GAK62479.1 - 9.6e-06 25.6 4.2 1.8e-05 24.7 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tfb5 PF06331.12 GAK62481.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Bud13 PF09736.9 GAK62483.1 - 1.2e-44 152.2 2.1 1.2e-44 152.2 2.1 1.6 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex bMG3 PF11974.8 GAK62483.1 - 0.0045 17.0 1.0 0.016 15.2 0.2 2.2 2 0 0 2 2 2 1 Bacterial alpha-2-macroglobulin MG3 domain LSM PF01423.22 GAK62484.1 - 3.9e-22 77.7 0.1 4.5e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAK62484.1 - 0.0045 17.1 0.0 0.0058 16.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 GAK62484.1 - 0.085 13.0 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain NUC153 PF08159.12 GAK62485.1 - 6.6e-15 54.6 11.2 5.2e-12 45.4 1.1 3.7 3 0 0 3 3 3 3 NUC153 domain BLUF PF04940.12 GAK62486.1 - 2.7e-30 104.3 0.0 4.1e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD SPX PF03105.19 GAK62486.1 - 0.045 13.7 5.4 0.053 13.4 5.4 1.2 1 0 0 1 1 1 0 SPX domain Autophagy_N PF03986.13 GAK62487.1 - 5.1e-41 139.8 0.0 1.1e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 GAK62487.1 - 4.9e-19 68.7 0.0 1.1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 GAK62487.1 - 2.2e-13 49.4 0.8 3.8e-13 48.7 0.8 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal IPPT PF01715.17 GAK62488.1 - 9.3e-57 192.5 0.0 5.4e-56 190.0 0.0 2.1 1 1 0 1 1 1 1 IPP transferase Peptidase_M1 PF01433.20 GAK62488.1 - 5.1e-40 137.4 0.0 1.7e-39 135.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAK62488.1 - 1.7e-36 124.7 0.0 4.2e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAK62488.1 - 8.5e-22 78.2 0.0 1.5e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain IPT PF01745.16 GAK62488.1 - 0.0071 15.8 0.1 0.04 13.3 0.1 2.1 2 0 0 2 2 2 1 Isopentenyl transferase PhoH PF02562.16 GAK62488.1 - 0.0074 15.8 0.0 0.023 14.2 0.2 1.6 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 GAK62488.1 - 0.021 14.4 0.1 0.064 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAK62488.1 - 0.028 14.8 0.2 0.37 11.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 GAK62488.1 - 0.14 12.7 0.1 17 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain Rad51 PF08423.11 GAK62488.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad51 RecA PF00154.21 GAK62488.1 - 0.38 10.2 1.5 1.2 8.5 0.3 2.2 2 1 1 3 3 3 0 recA bacterial DNA recombination protein AAA_33 PF13671.6 GAK62488.1 - 1.9 8.6 4.3 13 5.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Rad21_Rec8_N PF04825.13 GAK62490.1 - 3.1e-28 98.2 0.0 6.4e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAK62490.1 - 4.5e-09 35.5 0.6 4.5e-09 35.5 0.6 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein MFS_1 PF07690.16 GAK62491.1 - 2.5e-24 85.9 22.1 1.9e-18 66.6 10.8 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 GAK62491.1 - 1.3e-14 54.3 2.5 1.3e-14 54.3 2.5 2.9 3 0 0 3 3 3 1 Nodulin-like SH2_2 PF14633.6 GAK62493.1 - 1.5e-76 256.6 0.0 1.5e-76 256.6 0.0 1.9 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 GAK62493.1 - 5.2e-22 78.2 0.0 1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 GAK62493.1 - 5.7e-22 78.1 0.0 1.4e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 GAK62493.1 - 5e-21 75.3 0.7 1.2e-20 74.1 0.7 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 GAK62493.1 - 2.1e-18 66.7 26.0 2.1e-18 66.7 26.0 4.8 2 1 2 4 4 4 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 GAK62493.1 - 0.00053 20.8 0.8 0.00053 20.8 0.8 3.2 3 1 0 3 3 3 1 HHH domain HHH_3 PF12836.7 GAK62493.1 - 0.0025 18.0 0.0 0.0068 16.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.24 GAK62493.1 - 0.0081 16.2 0.0 0.029 14.5 0.0 2.0 1 0 0 1 1 1 1 SH2 domain DUF3381 PF11861.8 GAK62493.1 - 2.4 7.9 17.0 4.2 7.2 2.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) JAB PF01398.21 GAK62494.1 - 3.1e-24 85.2 0.0 4.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAK62494.1 - 2.7e-18 66.4 0.6 5.2e-18 65.5 0.3 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Syja_N PF02383.18 GAK62495.1 - 2.4e-90 303.1 0.2 3.2e-90 302.7 0.2 1.2 1 0 0 1 1 1 1 SacI homology domain GFO_IDH_MocA PF01408.22 GAK62496.1 - 1.2e-12 48.7 0.5 2.4e-12 47.7 0.5 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AMP-binding PF00501.28 GAK62496.1 - 0.02 13.5 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme CoA_binding_2 PF13380.6 GAK62496.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain BING4CT PF08149.11 GAK62497.1 - 7.1e-34 115.5 0.0 1.5e-31 108.0 0.0 3.2 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 GAK62497.1 - 1.7e-07 31.8 0.6 0.036 14.9 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 GAK62497.1 - 9.3e-05 21.6 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 GAK62497.1 - 0.0041 17.4 0.0 1.8 8.9 0.0 3.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RRP36 PF06102.12 GAK62498.1 - 1.3e-46 158.6 21.4 1.3e-46 158.6 21.4 2.8 3 0 0 3 3 3 1 rRNA biogenesis protein RRP36 DUF2408 PF10303.9 GAK62498.1 - 2.4 8.7 10.3 12 6.5 10.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CENP-P PF13096.6 GAK62499.1 - 0.12 12.0 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Atg14 PF10186.9 GAK62499.1 - 0.46 9.5 5.1 0.11 11.6 1.9 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Zn_clus PF00172.18 GAK62500.1 - 0.011 15.8 5.5 0.022 14.9 5.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 GAK62501.1 - 6.9e-97 325.4 0.0 8.3e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK62501.1 - 1.2e-05 25.2 1.3 0.00011 22.1 1.3 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2552 PF10827.8 GAK62501.1 - 0.098 12.8 0.1 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) WD40 PF00400.32 GAK62502.1 - 7.3e-20 70.9 10.8 6.7e-07 29.9 0.7 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK62502.1 - 1.6e-15 57.2 0.2 0.0023 18.2 0.1 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAK62502.1 - 5.1e-06 26.2 1.8 0.00013 21.7 0.4 2.4 2 0 0 2 2 2 1 PQQ-like domain eIF2A PF08662.11 GAK62502.1 - 0.004 17.1 0.4 6.6 6.6 0.1 3.5 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 GAK62502.1 - 0.0041 16.9 0.2 7.6 6.2 0.0 3.4 1 1 2 3 3 3 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 GAK62502.1 - 0.038 12.5 0.4 5.9 5.3 0.0 3.0 2 1 0 2 2 2 0 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 GAK62502.1 - 0.12 11.6 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CRT10 PF08728.10 GAK62502.1 - 0.18 10.0 0.0 0.3 9.2 0.0 1.3 1 0 0 1 1 1 0 CRT10 PQQ_3 PF13570.6 GAK62502.1 - 2.1 9.0 5.9 48 4.6 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain Brix PF04427.18 GAK62503.1 - 3.1e-23 82.9 0.0 4.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain MID_MedPIWI PF18296.1 GAK62503.1 - 0.66 9.7 3.8 3.2 7.5 0.8 2.2 2 0 0 2 2 2 0 MID domain of medPIWI COX7C PF02935.16 GAK62504.1 - 1e-15 57.7 1.3 1.2e-15 57.5 1.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CorA PF01544.18 GAK62505.1 - 2.7e-15 56.5 1.3 6.5e-08 32.2 0.1 3.6 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein FCH PF00611.23 GAK62506.1 - 7.6e-16 58.2 1.8 3.2e-15 56.2 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 GAK62506.1 - 3.1e-12 45.9 0.1 5.6e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK62506.1 - 4.7e-11 42.4 0.0 8.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAK62506.1 - 1.7e-08 34.0 0.0 4.5e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Glycos_transf_1 PF00534.20 GAK62507.1 - 1.6e-31 109.1 0.0 2e-30 105.6 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAK62507.1 - 4.1e-25 88.7 0.4 9.2e-25 87.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAK62507.1 - 1.2e-24 87.3 0.1 3.4e-24 85.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAK62507.1 - 5.5e-15 56.2 2.3 5.8e-15 56.1 0.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAK62507.1 - 0.025 15.0 0.1 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 ELP6 PF09807.9 GAK62508.1 - 2.6e-12 46.7 0.1 8.1e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 GAK62508.1 - 0.00031 20.3 0.1 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Elongator subunit Iki1 ANAPC4_WD40 PF12894.7 GAK62509.1 - 2.5e-10 40.5 0.4 0.0016 18.7 0.0 5.6 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAK62509.1 - 1.9e-05 25.3 14.7 0.42 11.6 0.0 6.7 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.11 GAK62509.1 - 0.00013 21.9 0.0 0.78 9.6 0.0 4.2 5 0 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 GAK62509.1 - 0.071 11.9 0.2 52 2.4 0.0 3.7 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 GAK62509.1 - 0.091 12.7 4.5 6 6.9 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 GAK62510.1 - 2.6e-39 132.9 0.1 2.1e-20 72.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GAK62510.1 - 1.2e-14 55.2 1.3 6e-14 52.9 1.3 2.2 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 GAK62510.1 - 0.0002 21.1 0.0 0.0011 18.7 0.0 2.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 GAK62510.1 - 0.00089 19.3 0.1 0.005 16.9 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 GAK62510.1 - 0.096 12.7 0.1 17 5.5 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif CAP_GLY PF01302.25 GAK62511.1 - 7.4e-26 90.0 1.0 1.1e-25 89.4 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 GAK62511.1 - 6.7e-13 48.9 0.0 7.7e-12 45.5 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-like domain Acetyltransf_10 PF13673.7 GAK62512.1 - 3e-08 33.7 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK62512.1 - 8.7e-06 26.1 0.1 2.8e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 GAK62512.1 - 2.9e-05 24.7 0.0 0.00023 21.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK62512.1 - 0.00022 21.5 0.0 0.0023 18.1 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAK62512.1 - 0.0041 17.0 0.1 0.023 14.7 0.1 2.0 2 0 0 2 2 2 1 FR47-like protein SNAP PF14938.6 GAK62514.1 - 2.8e-99 332.1 16.4 3.1e-99 331.9 16.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GAK62514.1 - 1.8e-05 24.9 18.4 0.018 15.3 0.6 4.4 1 1 4 5 5 5 3 Tetratricopeptide repeat Spatacsin_C PF14649.6 GAK62514.1 - 0.0039 16.4 1.0 0.0039 16.4 1.0 2.0 1 1 1 2 2 2 1 Spatacsin C-terminus RNA_pol_Rpb6 PF01192.22 GAK62514.1 - 0.071 13.0 0.1 1.4 8.9 0.3 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb6 TPR_6 PF13174.6 GAK62514.1 - 0.56 11.0 18.5 5.1 7.9 0.4 5.9 4 2 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAK62514.1 - 1.6 8.7 18.0 13 5.8 1.7 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAK62514.1 - 9.6 6.0 19.5 7.8 6.3 0.1 5.6 3 2 3 6 6 6 0 TPR repeat ELO PF01151.18 GAK62516.1 - 1.6e-57 194.9 8.5 2e-57 194.6 8.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PK PF00224.21 GAK62517.1 - 9.6e-161 534.4 5.5 1.2e-160 534.1 5.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAK62517.1 - 2.7e-36 124.3 0.0 7e-36 123.0 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAK62517.1 - 0.00094 18.4 0.2 0.0029 16.8 0.2 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 GAK62517.1 - 0.044 12.8 0.3 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF218 PF02698.17 GAK62517.1 - 0.085 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain 2OG-FeII_Oxy_2 PF13532.6 GAK62519.1 - 1.3e-21 77.7 0.3 2.1e-21 77.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-AN1 PF01428.16 GAK62520.1 - 5.4e-17 61.7 35.2 1.6e-08 34.6 15.6 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger COesterase PF00135.28 GAK62521.1 - 1e-72 245.7 0.0 1.7e-72 245.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK62521.1 - 8.5e-12 45.4 0.4 7.1e-11 42.4 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAK62521.1 - 0.00012 21.7 0.3 0.00023 20.7 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family ESSS PF10183.9 GAK62522.1 - 7.8e-13 48.6 0.2 1.1e-12 48.1 0.2 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PH PF00169.29 GAK62523.1 - 6.5e-35 119.8 0.5 1.7e-19 70.3 0.9 3.2 3 0 0 3 3 3 3 PH domain PH_3 PF14593.6 GAK62523.1 - 1.4e-17 63.7 5.2 9.3e-09 35.3 1.3 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 GAK62523.1 - 7.8e-15 55.2 10.2 1.3e-06 28.7 6.3 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 GAK62523.1 - 1.1e-09 38.5 3.9 7.1e-07 29.4 1.4 2.6 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 GAK62523.1 - 0.00019 21.8 0.7 0.11 12.9 0.9 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain PH_15 PF17339.2 GAK62523.1 - 0.00024 20.9 1.1 0.018 14.9 0.5 2.2 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 GAK62523.1 - 0.002 17.9 0.5 0.051 13.4 0.3 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 GAK62523.1 - 0.024 14.5 1.2 13 5.5 0.0 3.2 2 1 1 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 GAK62523.1 - 0.14 12.3 0.8 17 5.5 0.0 2.8 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology CENP-B_dimeris PF09026.10 GAK62523.1 - 4.4 7.8 8.7 21 5.6 3.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cation_efflux PF01545.21 GAK62524.1 - 3.3e-44 151.0 0.1 6.3e-44 150.1 0.1 1.5 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAK62524.1 - 2.9e-07 30.5 0.4 6.2e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter SelP_N PF04592.14 GAK62524.1 - 0.88 8.9 5.9 1.8 7.9 5.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region adh_short PF00106.25 GAK62525.1 - 2.3e-85 285.0 13.3 1.5e-42 145.3 4.3 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK62525.1 - 1.4e-68 231.0 16.3 2e-35 122.5 3.4 3.2 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 GAK62525.1 - 7.6e-33 112.7 0.0 1.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 GAK62525.1 - 6.2e-32 111.0 7.1 2.1e-16 60.4 0.6 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 GAK62525.1 - 5.7e-05 22.5 0.1 0.015 14.7 0.1 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 GAK62525.1 - 0.018 14.9 5.9 0.43 10.4 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 GAK62525.1 - 0.057 13.4 5.1 3 7.9 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) MaoC_dehydrat_N PF13452.6 GAK62525.1 - 0.068 13.3 0.0 7.3 6.7 0.0 2.4 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase PglL_A PF15864.5 GAK62525.1 - 0.93 9.3 8.1 5.5 6.8 1.0 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase Sec7 PF01369.20 GAK62526.1 - 9.4e-34 116.7 0.2 1.5e-33 116.1 0.2 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 GAK62526.1 - 1.2e-13 51.5 0.0 2.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAK62526.1 - 1.1e-10 41.9 0.0 4.4e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_6 PF15406.6 GAK62526.1 - 0.0066 16.7 2.6 0.0097 16.2 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Tom7 PF08038.12 GAK62527.1 - 3.8e-19 68.1 0.1 1e-18 66.7 0.1 1.8 1 0 0 1 1 1 1 TOM7 family B277 PF17623.2 GAK62527.1 - 0.089 11.9 1.2 0.14 11.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function TetR_C_24 PF17932.1 GAK62527.1 - 0.22 11.8 8.9 1 9.7 0.5 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Prominin PF05478.11 GAK62527.1 - 0.3 9.0 3.7 0.41 8.5 3.7 1.1 1 0 0 1 1 1 0 Prominin ANAPC5 PF12862.7 GAK62528.1 - 7.5e-12 45.2 3.2 1.4e-11 44.3 0.2 3.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 GAK62528.1 - 0.032 14.4 0.1 0.63 10.4 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAK62528.1 - 0.061 13.6 0.2 0.061 13.6 0.2 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAK62528.1 - 0.071 13.3 0.2 9.1 6.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAK62528.1 - 0.27 11.2 11.2 0.36 10.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK62528.1 - 0.38 11.7 0.1 0.38 11.7 0.1 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat 4HBT PF03061.22 GAK62529.1 - 0.00018 21.8 0.1 0.00036 20.8 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Kdo PF06293.14 GAK62530.1 - 7.8e-06 25.4 0.1 6.9e-05 22.3 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK62530.1 - 1.9e-05 24.7 0.6 0.00091 19.2 0.3 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 GAK62530.1 - 3e-05 23.5 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 GAK62530.1 - 0.0067 16.0 0.0 0.48 10.0 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 GAK62530.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase EcKinase PF02958.20 GAK62530.1 - 0.22 10.8 0.0 0.56 9.5 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase Fasciclin PF02469.22 GAK62531.1 - 1.6e-23 83.3 4.0 2.1e-16 60.3 0.3 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF4406 PF14359.6 GAK62531.1 - 0.15 12.5 0.0 0.65 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4406) Sec61_beta PF03911.16 GAK62532.1 - 9.9e-18 63.9 2.2 1.3e-17 63.6 2.2 1.1 1 0 0 1 1 1 1 Sec61beta family RecQ5 PF06959.11 GAK62532.1 - 0.1 12.6 2.4 0.11 12.5 2.4 1.0 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) CHCH PF06747.13 GAK62533.1 - 1.1e-05 25.4 1.1 1.4e-05 25.1 1.1 1.1 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 GAK62533.1 - 0.00068 19.6 0.7 0.00091 19.2 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 GAK62533.1 - 0.047 13.7 0.1 0.072 13.1 0.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HTH_5 PF01022.20 GAK62533.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Spc7 PF08317.11 GAK62534.1 - 3.9e-45 154.1 4.9 3.9e-45 154.1 4.9 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Aminotran_3 PF00202.21 GAK62534.1 - 0.045 12.4 0.2 0.38 9.4 0.2 2.0 1 1 0 1 1 1 0 Aminotransferase class-III DUF2605 PF10792.9 GAK62534.1 - 0.048 13.6 1.1 0.17 11.9 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) COG5 PF10392.9 GAK62534.1 - 0.07 13.3 5.0 0.22 11.7 5.0 1.9 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Atg14 PF10186.9 GAK62534.1 - 0.48 9.5 6.6 0.3 10.1 3.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 GAK62534.1 - 1.4 9.3 9.0 6.8 7.0 2.4 3.1 1 1 1 2 2 2 0 Uncharacterized conserved protein FapA PF03961.13 GAK62534.1 - 6.9 5.2 7.6 1.4 7.4 4.0 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Phage_TAC_4 PF08748.11 GAK62534.1 - 8.3 6.7 12.1 0.075 13.4 0.6 3.2 2 1 1 3 3 3 0 Phage tail assembly chaperone Dus PF01207.17 GAK62535.1 - 5.4e-46 157.1 0.1 1.6e-45 155.5 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 GAK62535.1 - 0.0034 16.6 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Spt5_N PF11942.8 GAK62536.1 - 1.8e-19 70.6 17.1 1.8e-19 70.6 17.1 2.5 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 GAK62536.1 - 1.6e-18 66.4 0.0 2.9e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 GAK62536.1 - 3.8e-18 64.8 9.1 1.1e-07 31.6 0.0 5.9 6 0 0 6 6 6 4 KOW motif CTD PF12815.7 GAK62536.1 - 4.7e-10 39.9 13.9 1.2e-09 38.6 13.9 1.8 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 CDC45 PF02724.14 GAK62536.1 - 2.7 6.2 24.1 5.3 5.2 24.1 1.4 1 0 0 1 1 1 0 CDC45-like protein GTP_EFTU PF00009.27 GAK62537.1 - 2.5e-56 190.3 0.1 3.8e-56 189.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAK62537.1 - 8.5e-30 103.3 0.0 1.7e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAK62537.1 - 5.5e-17 61.9 3.6 1.4e-16 60.6 3.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAK62537.1 - 8.6e-05 22.6 0.1 0.00018 21.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK62537.1 - 0.0057 16.6 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 GAK62537.1 - 0.0097 15.5 0.5 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAK62537.1 - 0.062 13.0 0.2 7.3 6.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-SNAP50_C PF12251.8 GAK62538.1 - 1.2e-09 38.2 0.0 1.9e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C2H2 PF00096.26 GAK62539.1 - 9.2e-35 117.2 61.2 2.6e-05 24.4 0.1 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK62539.1 - 2.6e-21 74.5 61.5 0.057 14.3 0.1 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK62539.1 - 5.9e-10 39.1 43.6 1.1e-05 25.6 0.2 10.0 10 1 0 10 10 10 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 GAK62539.1 - 9.8e-10 38.6 21.9 0.0007 19.9 4.5 5.1 3 1 2 5 5 5 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAK62539.1 - 9.5e-08 32.6 37.0 0.0053 17.3 0.3 8.0 7 2 1 8 8 8 3 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 GAK62539.1 - 0.0041 17.1 0.1 0.0041 17.1 0.1 7.4 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAK62539.1 - 0.02 15.0 17.1 11 6.2 1.4 5.9 4 1 3 7 7 7 0 Aberrant zinc-finger zf-C2H2_12 PF18658.1 GAK62539.1 - 0.86 9.2 11.4 2.1 8.0 0.2 4.1 4 1 1 5 5 5 0 Zinc-finger C2H2-type IBR PF01485.21 GAK62539.1 - 2.7 8.3 29.9 0.83 9.9 0.9 5.5 4 2 0 4 4 4 0 IBR domain, a half RING-finger domain FYDLN_acid PF09538.10 GAK62539.1 - 4.3 8.1 26.7 0.11 13.2 1.0 5.5 5 1 1 6 6 6 0 Protein of unknown function (FYDLN_acid) Acetyltransf_3 PF13302.7 GAK62540.1 - 1.1e-21 77.9 0.0 1.5e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAK62540.1 - 9.5e-06 25.4 0.6 0.37 10.5 0.0 3.1 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK62540.1 - 0.023 15.1 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK62540.1 - 0.029 14.6 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family FR47 PF08445.10 GAK62540.1 - 0.044 13.8 0.0 0.096 12.7 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Apolipoprotein PF01442.18 GAK62541.1 - 2.7e-10 40.5 63.7 0.00022 21.1 1.4 4.5 1 1 3 4 4 4 4 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GAK62541.1 - 2.1e-05 25.0 88.3 0.078 13.6 1.4 10.3 1 1 10 12 12 12 6 Bacterial protein of unknown function (DUF883) ApoO PF09769.9 GAK62541.1 - 1.5 8.8 20.9 0.36 10.8 0.4 5.7 2 2 2 5 5 5 0 Apolipoprotein O PAF-AH_p_II PF03403.13 GAK62542.1 - 5.5e-43 146.9 0.0 3.2e-40 137.8 0.0 4.0 3 1 0 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 GAK62542.1 - 3.7e-07 29.7 0.0 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAK62542.1 - 0.0011 17.9 0.0 0.02 13.8 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 GAK62542.1 - 0.026 13.5 0.0 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_1 PF00561.20 GAK62542.1 - 0.091 12.4 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hid1 PF12722.7 GAK62542.1 - 0.35 8.9 0.8 0.66 8.0 0.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 GAK62542.1 - 2.6 6.6 5.6 4.7 5.8 5.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ADH_zinc_N PF00107.26 GAK62544.1 - 9.9e-27 93.5 0.3 1.7e-26 92.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK62544.1 - 2.8e-13 51.1 0.0 6.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK62544.1 - 1.6e-09 37.6 0.0 3.8e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAK62544.1 - 0.00093 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Abhydrolase_2 PF02230.16 GAK62545.1 - 2.5e-55 187.6 0.0 3.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAK62545.1 - 4.7e-08 32.6 0.2 0.01 15.2 0.2 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK62545.1 - 3.1e-07 31.2 0.1 4.1e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAK62545.1 - 0.00013 21.7 0.6 0.016 14.8 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAK62545.1 - 0.00036 20.1 0.2 0.018 14.5 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 GAK62545.1 - 0.0013 18.2 0.1 0.3 10.6 0.1 2.2 1 1 1 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.20 GAK62545.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 GAK62545.1 - 0.0025 17.7 0.2 0.051 13.4 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 GAK62545.1 - 0.0027 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 GAK62545.1 - 0.0032 17.2 0.0 0.024 14.3 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 GAK62545.1 - 0.017 13.8 0.1 0.026 13.2 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Cutinase PF01083.22 GAK62545.1 - 0.036 14.0 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Cutinase Lipase_3 PF01764.25 GAK62545.1 - 0.049 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2103 PF09876.9 GAK62546.1 - 0.05 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2103) Abhydrolase_3 PF07859.13 GAK62547.1 - 9.8e-10 38.6 0.3 1.5e-09 38.0 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK62547.1 - 3.4e-07 31.1 1.3 4.5e-07 30.7 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK62547.1 - 3.4e-06 26.5 0.1 6.8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 COesterase PF00135.28 GAK62547.1 - 0.0018 17.2 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF900 PF05990.12 GAK62547.1 - 0.032 13.7 0.0 1 8.8 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 GAK62547.1 - 0.05 13.2 0.2 0.084 12.5 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 GAK62547.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 GAK62547.1 - 0.16 11.4 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cellulase PF00150.18 GAK62548.1 - 2.7e-13 50.0 0.0 5.4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Acetyltransf_1 PF00583.25 GAK62549.1 - 3e-08 33.9 0.0 7.9e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Mss4 PF04421.13 GAK62549.1 - 8.9e-08 32.2 3.9 0.011 15.9 3.8 3.0 2 1 0 2 2 2 2 Mss4 protein Acetyltransf_7 PF13508.7 GAK62549.1 - 5.1e-07 30.0 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAK62549.1 - 0.00026 20.9 0.0 0.0033 17.4 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK62549.1 - 0.0096 15.9 0.0 0.066 13.2 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 GAK62549.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAK62549.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 GAK62549.1 - 0.053 13.5 0.0 0.33 10.9 0.0 2.2 3 0 0 3 3 2 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 GAK62549.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NARP1 PF12569.8 GAK62549.1 - 0.12 11.3 11.4 0.22 10.4 11.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ATP-synt_E PF05680.12 GAK62549.1 - 0.3 11.5 8.4 0.65 10.4 8.4 1.5 1 0 0 1 1 1 0 ATP synthase E chain U1snRNP70_N PF12220.8 GAK62549.1 - 0.58 10.8 9.0 2.2 9.0 9.0 2.0 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DDHD PF02862.17 GAK62549.1 - 1.4 9.0 8.7 0.72 10.0 0.4 2.7 3 0 0 3 3 3 0 DDHD domain PPL5 PF18168.1 GAK62549.1 - 1.9 7.7 6.2 3.8 6.7 6.2 1.4 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 GAK62549.1 - 3.5 5.8 9.3 5.7 5.1 9.3 1.3 1 0 0 1 1 1 0 CDC45-like protein AP3D1 PF06375.11 GAK62549.1 - 4.3 7.6 18.7 0.027 14.7 9.6 1.9 3 0 0 3 3 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 GAK62549.1 - 7 6.3 6.1 13 5.5 6.1 1.3 1 0 0 1 1 1 0 Connexin DUF2992 PF11208.8 GAK62549.1 - 8.3 6.7 19.2 15 5.9 19.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Polysacc_deac_1 PF01522.21 GAK62550.1 - 1.2e-13 51.1 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase GFA PF04828.14 GAK62550.1 - 8.8e-08 32.4 0.7 4.9e-06 26.8 0.7 2.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MbtH PF03621.13 GAK62550.1 - 0.092 12.2 0.1 0.27 10.7 0.1 1.8 1 0 0 1 1 1 0 MbtH-like protein zinc_ribbon_4 PF13717.6 GAK62550.1 - 0.63 10.0 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Usp PF00582.26 GAK62551.1 - 1.7e-18 67.5 1.5 2.3e-18 67.1 1.5 1.2 1 0 0 1 1 1 1 Universal stress protein family Arm-DNA-bind_3 PF13356.6 GAK62551.1 - 0.045 14.1 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 Arm DNA-binding domain FMN_dh PF01070.18 GAK62553.1 - 4.4e-119 397.6 0.1 5.5e-119 397.3 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAK62553.1 - 3.1e-17 62.5 0.0 5.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAK62553.1 - 1.9e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAK62553.1 - 0.0003 19.9 0.2 0.0011 18.0 0.2 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain A_deaminase_N PF08451.11 GAK62553.1 - 0.0078 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Peripla_BP_4 PF13407.6 GAK62553.1 - 0.024 14.2 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain His_biosynth PF00977.21 GAK62553.1 - 0.037 13.5 0.0 9.9 5.5 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein NMO PF03060.15 GAK62553.1 - 0.04 13.3 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase AidB_N PF18158.1 GAK62554.1 - 2.1e-18 66.7 0.0 5.7e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAK62554.1 - 5.2e-15 55.9 0.2 5.2e-15 55.9 0.2 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAK62554.1 - 2.4e-14 53.3 0.0 4.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAK62554.1 - 0.073 13.7 0.0 0.72 10.5 0.0 2.6 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain DUF1770 PF08589.10 GAK62555.1 - 4.2e-08 34.1 0.4 5.5e-07 30.5 0.2 2.1 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) SpoIIE PF07228.12 GAK62556.1 - 5.1e-14 52.6 0.0 7.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAK62556.1 - 0.00038 20.2 0.0 0.041 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Metallophos PF00149.28 GAK62557.1 - 9.2e-09 36.1 0.0 1.7e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UDPG_MGDP_dh_N PF03721.14 GAK62558.1 - 5.6e-59 198.9 0.2 3.6e-58 196.2 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 GAK62558.1 - 2.2e-32 111.6 0.5 1e-31 109.5 0.2 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 GAK62558.1 - 1.1e-31 108.9 0.0 2.6e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 GAK62558.1 - 0.011 16.0 0.1 0.44 10.7 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amidase PF01425.21 GAK62559.1 - 3e-86 290.2 0.0 1.1e-64 219.0 0.4 2.1 1 1 1 2 2 2 2 Amidase MFS_1 PF07690.16 GAK62560.1 - 2.7e-30 105.5 37.9 2.7e-30 105.5 37.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 GAK62560.1 - 0.88 9.9 6.4 4.3 7.7 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Aminotran_4 PF01063.19 GAK62561.1 - 3.7e-26 92.4 0.0 1.1e-25 90.8 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV ADH_zinc_N PF00107.26 GAK62562.1 - 8.2e-11 42.0 0.4 1.5e-09 37.9 0.3 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK62562.1 - 7.9e-06 27.0 0.0 1.9e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK62562.1 - 0.00039 20.3 0.0 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TFIID-18kDa PF02269.16 GAK62563.1 - 1.4e-28 98.8 0.7 6e-28 96.7 0.3 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 GAK62563.1 - 2.9 8.3 6.8 0.37 11.1 0.2 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Fungal_trans PF04082.18 GAK62564.1 - 2.7e-27 95.5 0.0 4.9e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62564.1 - 2.5e-11 43.5 8.8 2.5e-11 43.5 8.8 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prp19 PF08606.11 GAK62565.1 - 9.9e-31 105.5 2.0 1.8e-30 104.7 2.0 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 GAK62565.1 - 3.9e-27 94.0 1.5 0.0025 18.6 0.0 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK62565.1 - 1.3e-15 57.5 0.1 0.00016 21.9 0.0 5.2 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 GAK62565.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ge1_WD40 PF16529.5 GAK62565.1 - 0.19 10.7 0.1 22 3.8 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mpv17_PMP22 PF04117.12 GAK62566.1 - 2.4e-05 24.5 5.1 0.00018 21.7 3.3 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family MatE PF01554.18 GAK62566.1 - 0.026 14.2 2.9 0.3 10.7 0.2 2.4 1 1 1 2 2 2 0 MatE DUF1769 PF08588.10 GAK62567.1 - 3.3e-17 62.4 0.5 6.3e-17 61.5 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Dak1 PF02733.17 GAK62568.1 - 2.4e-102 342.0 0.0 3.3e-102 341.6 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GAK62568.1 - 6e-45 153.3 0.7 6e-45 153.3 0.7 2.2 2 0 0 2 2 2 1 DAK2 domain adh_short_C2 PF13561.6 GAK62569.1 - 5.4e-62 209.4 0.2 7.3e-62 209.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK62569.1 - 1.3e-46 158.6 0.5 1.9e-46 158.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK62569.1 - 1.9e-14 54.0 0.1 3.3e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAK62569.1 - 0.00016 21.3 0.0 0.0004 19.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAK62569.1 - 0.009 15.2 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FTR1 PF03239.14 GAK62571.1 - 5.8e-53 180.0 7.6 5.4e-35 121.0 4.5 2.1 2 0 0 2 2 2 2 Iron permease FTR1 family LPD15 PF18828.1 GAK62571.1 - 0.22 11.4 0.8 0.53 10.2 0.8 1.6 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 DUF2721 PF11026.8 GAK62571.1 - 0.59 10.0 5.5 0.14 12.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) FtsX PF02687.21 GAK62571.1 - 4.7 7.8 9.6 0.99 9.9 0.3 3.0 2 1 0 2 2 2 0 FtsX-like permease family Cu-oxidase_2 PF07731.14 GAK62572.1 - 6e-41 139.4 6.4 8.6e-39 132.4 1.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAK62572.1 - 1.3e-37 129.4 0.1 1.9e-34 119.1 0.1 2.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAK62572.1 - 1.5e-31 108.9 0.5 5.4e-27 94.2 0.1 3.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 GAK62572.1 - 0.16 12.1 0.0 3.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Cupredoxin-like domain PAN_4 PF14295.6 GAK62573.1 - 0.029 14.3 3.2 0.05 13.5 0.1 2.7 2 0 0 2 2 2 0 PAN domain GET2 PF08690.10 GAK62573.1 - 1.3 8.6 5.9 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 GET complex subunit GET2 Alpha-amylase PF00128.24 GAK62574.1 - 1.5e-67 228.5 0.0 2.5e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 GAK62574.1 - 4e-16 59.1 0.4 7.7e-16 58.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 GAK62574.1 - 0.18 10.8 1.3 0.28 10.2 1.3 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain MFS_1 PF07690.16 GAK62575.1 - 3.1e-22 79.0 38.0 9.2e-13 47.8 19.5 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_cc PF11790.8 GAK62576.1 - 6.2e-62 209.3 9.9 1.7e-35 122.8 6.4 2.6 2 1 1 3 3 3 2 Glycosyl hydrolase catalytic core IMS PF00817.20 GAK62577.1 - 9.7e-38 129.5 0.0 1.8e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 GAK62577.1 - 1.4e-06 29.0 0.0 1e-05 26.2 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 GAK62577.1 - 4.8e-05 22.8 1.4 0.00023 20.7 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger MMtag PF10159.9 GAK62578.1 - 3.9e-27 94.3 1.6 3.9e-27 94.3 1.6 2.5 2 0 0 2 2 2 1 Multiple myeloma tumor-associated CTP_transf_like PF01467.26 GAK62578.1 - 3e-23 82.6 0.1 7.9e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF1479 PF07350.12 GAK62579.1 - 7.8e-05 21.6 0.0 0.0007 18.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) PhyH PF05721.13 GAK62579.1 - 0.00069 19.9 0.0 0.0098 16.2 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 GAK62579.1 - 0.0023 18.8 0.0 0.0078 17.1 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 GAK62579.1 - 0.0098 16.3 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase TauD PF02668.16 GAK62579.1 - 0.027 14.3 0.2 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_S15 PF02129.18 GAK62580.1 - 4.2e-34 118.4 0.0 8.4e-33 114.1 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAK62580.1 - 6.4e-34 117.9 0.0 8.6e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 GAK62580.1 - 0.21 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 GAK62581.1 - 4.2e-18 65.4 28.1 4.2e-18 65.4 28.1 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK62581.1 - 4.3e-11 42.3 8.5 4.3e-11 42.3 8.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter NnrU PF07298.11 GAK62581.1 - 0.19 11.2 9.3 0.91 9.0 0.2 3.0 3 0 0 3 3 3 0 NnrU protein Fungal_trans PF04082.18 GAK62582.1 - 2.4e-17 62.8 0.0 4.9e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62582.1 - 0.00033 20.7 6.1 0.00033 20.7 6.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 GAK62582.1 - 0.00048 20.7 10.1 0.16 12.9 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAK62582.1 - 0.00096 19.5 12.2 0.008 16.6 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type TerY_C PF15616.6 GAK62582.1 - 0.048 13.8 0.1 0.86 9.7 0.1 2.3 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C2HC_2 PF13913.6 GAK62582.1 - 0.089 12.7 9.3 0.52 10.3 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 GAK62582.1 - 1.3 9.4 4.7 10 6.5 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 GAK62582.1 - 1.3 9.0 3.5 0.45 10.5 0.4 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.6 GAK62582.1 - 1.7 8.7 8.4 1.9 8.6 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK62582.1 - 2 9.0 7.9 1.7 9.2 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Ytp1 PF10355.9 GAK62583.1 - 1e-56 192.2 26.2 2.5e-56 190.9 20.2 2.6 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAK62583.1 - 3e-29 100.9 2.7 3e-29 100.9 2.7 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3760 PF12586.8 GAK62584.1 - 0.0026 17.9 0.9 0.0066 16.6 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3760) Zip PF02535.22 GAK62585.1 - 1.4e-61 208.6 13.7 2.3e-61 207.9 13.7 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Sigma70_r4_2 PF08281.12 GAK62585.1 - 1.7e-10 40.4 0.1 1.2e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_38 PF13936.6 GAK62585.1 - 2.2e-09 36.9 0.4 4.1e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 GAK62585.1 - 5.5e-08 32.4 0.1 0.00082 19.1 0.1 2.4 2 0 0 2 2 2 2 Homeodomain-like domain GerE PF00196.19 GAK62585.1 - 1.9e-07 30.5 1.0 0.011 15.3 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 GAK62585.1 - 0.0003 20.3 0.1 0.00079 18.9 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 GAK62585.1 - 0.00055 20.0 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.12 GAK62585.1 - 0.00058 19.7 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 2 Putative ATPase subunit of terminase (gpP-like) HTH_32 PF13565.6 GAK62585.1 - 0.0012 19.5 0.2 0.015 15.9 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_35 PF13693.6 GAK62585.1 - 0.0022 18.0 0.1 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 GAK62585.1 - 0.015 15.3 0.2 0.081 13.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 GAK62585.1 - 0.025 14.6 3.3 3 7.9 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix HTH_40 PF14493.6 GAK62585.1 - 0.12 12.9 0.1 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain adh_short PF00106.25 GAK62586.1 - 8.7e-41 139.5 0.0 1.1e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK62586.1 - 2.8e-19 69.6 0.0 3.6e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK62586.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAK62586.1 - 0.0017 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAK62586.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAK62586.1 - 0.043 13.2 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 GAK62586.1 - 0.052 14.1 0.0 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DJ-1_PfpI PF01965.24 GAK62587.1 - 1.5e-11 44.4 0.0 3e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAK62587.1 - 0.00018 21.2 0.0 0.0018 18.0 0.0 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like MFS_1 PF07690.16 GAK62588.1 - 4e-21 75.3 46.5 6.9e-15 54.8 24.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK62588.1 - 6.5e-16 58.2 24.2 8.5e-16 57.8 8.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter UPRTase PF14681.6 GAK62589.1 - 9.4e-70 234.3 0.0 1.1e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAK62589.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain adh_short_C2 PF13561.6 GAK62590.1 - 3.3e-53 180.7 3.7 4.4e-53 180.2 3.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK62590.1 - 8.5e-44 149.4 0.8 1.3e-43 148.8 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK62590.1 - 2.9e-08 33.8 1.5 7.1e-08 32.6 1.5 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAK62590.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1657 PF07870.11 GAK62590.1 - 0.14 12.1 1.0 0.26 11.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Oxidored-like PF09791.9 GAK62592.1 - 1.4e-07 31.0 9.0 3.1e-07 30.0 9.0 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Abhydrolase_1 PF00561.20 GAK62592.1 - 0.00033 20.4 0.3 0.00099 18.8 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold CUE PF02845.16 GAK62593.1 - 1.3e-07 31.2 0.2 0.0012 18.5 0.0 4.0 4 0 0 4 4 4 2 CUE domain Smr PF01713.21 GAK62593.1 - 8e-07 29.3 1.6 1e-06 29.0 0.1 2.0 2 0 0 2 2 2 1 Smr domain DMA PF03474.14 GAK62593.1 - 0.00084 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif DUF1771 PF08590.10 GAK62593.1 - 0.00085 19.6 5.0 0.00085 19.6 5.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) TRAM_LAG1_CLN8 PF03798.16 GAK62594.1 - 1.8e-30 106.1 10.2 2.3e-30 105.8 10.2 1.1 1 0 0 1 1 1 1 TLC domain RRF PF01765.19 GAK62595.1 - 3.7e-38 131.0 0.0 5.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Hydrolase_4 PF12146.8 GAK62596.1 - 2.5e-37 128.4 0.4 2.8e-21 75.9 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAK62596.1 - 2.4e-07 30.7 0.1 9e-06 25.5 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK62596.1 - 2.3e-05 25.1 3.3 3.8e-05 24.4 3.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAK62596.1 - 0.019 14.5 0.1 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family HECT PF00632.25 GAK62597.1 - 3.1e-33 115.6 0.0 4e-23 82.4 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Form_Nir_trans PF01226.17 GAK62598.1 - 1.3e-63 214.5 21.3 1.7e-63 214.1 21.3 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter DUF572 PF04502.13 GAK62598.1 - 0.028 14.1 14.8 0.04 13.6 14.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) ARGLU PF15346.6 GAK62598.1 - 1.3 8.9 25.5 2.3 8.1 25.5 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Herpes_env PF01673.18 GAK62598.1 - 1.3 7.8 7.2 2.4 7.0 7.2 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Hydantoinase_B PF02538.14 GAK62599.1 - 3.9e-210 698.7 0.4 5.5e-210 698.1 0.4 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Epimerase PF01370.21 GAK62600.1 - 8.5e-16 58.1 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK62600.1 - 2.7e-11 43.0 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAK62600.1 - 7.5e-10 38.7 0.0 3.1e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAK62600.1 - 1e-08 34.7 0.0 1.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAK62600.1 - 3.1e-08 33.1 0.0 0.0011 18.2 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 GAK62600.1 - 0.06 12.5 0.0 0.55 9.3 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Lyase_aromatic PF00221.19 GAK62601.1 - 6.9e-147 489.8 1.9 9.4e-147 489.4 1.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase C5-epim_C PF06662.13 GAK62602.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus MFS_3 PF05977.13 GAK62602.1 - 0.16 10.4 8.4 0.8 8.0 8.1 2.0 1 1 0 1 1 1 0 Transmembrane secretion effector Xan_ur_permease PF00860.20 GAK62605.1 - 2.3e-59 201.1 27.0 2.3e-59 201.1 27.0 1.5 2 0 0 2 2 2 1 Permease family DUF2627 PF11118.8 GAK62605.1 - 0.27 11.8 2.3 1.2 9.7 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) MFS_MOT1 PF16983.5 GAK62605.1 - 2.7 8.4 23.9 0.074 13.5 2.8 4.4 3 1 0 4 4 4 0 Molybdate transporter of MFS superfamily Mob_synth_C PF06463.13 GAK62606.1 - 3.8e-34 117.4 0.0 4.1e-33 114.0 0.0 2.4 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 GAK62606.1 - 2.1e-28 99.8 0.0 3.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAK62606.1 - 3e-07 30.8 0.0 7.8e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAK62606.1 - 0.00074 19.6 0.0 0.0025 17.9 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain MoaC PF01967.21 GAK62607.1 - 2.1e-50 170.4 2.0 3.3e-50 169.7 2.0 1.3 1 0 0 1 1 1 1 MoaC family Nop16 PF09420.10 GAK62608.1 - 7.5e-58 196.0 1.3 8.6e-58 195.8 1.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF775 PF05603.12 GAK62609.1 - 2.4e-46 157.8 0.0 2.9e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) EXS PF03124.14 GAK62610.1 - 8.8e-100 334.2 1.1 1.1e-99 334.0 1.1 1.1 1 0 0 1 1 1 1 EXS family Abhydrolase_5 PF12695.7 GAK62611.1 - 0.00041 20.2 0.4 0.002 17.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK62611.1 - 0.04 13.2 0.0 0.09 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 GAK62611.1 - 0.044 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF818 PF05677.12 GAK62611.1 - 0.19 10.6 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DS PF01916.17 GAK62612.1 - 1.8e-132 441.0 0.0 2.1e-132 440.7 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF494 PF04361.13 GAK62612.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) ICE2 PF08426.10 GAK62613.1 - 1.7e-60 205.2 11.5 5.5e-35 121.3 1.9 3.1 2 1 0 2 2 2 2 ICE2 RXT2_N PF08595.11 GAK62613.1 - 0.61 10.1 1.6 1 9.4 1.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Fungal_trans PF04082.18 GAK62614.1 - 1.7e-12 46.9 0.0 3.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62614.1 - 2e-07 31.0 8.8 3.5e-07 30.2 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA_3 PF07730.13 GAK62614.1 - 0.092 13.3 0.3 0.092 13.3 0.3 2.6 2 0 0 2 2 2 0 Histidine kinase MAGUK_N_PEST PF10608.9 GAK62614.1 - 5.8 7.4 6.6 0.36 11.3 0.7 2.0 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK AA_permease_2 PF13520.6 GAK62615.1 - 2.6e-47 161.6 39.3 3.5e-47 161.2 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease YiiD_C PF09500.10 GAK62615.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) zf-UBR PF02207.20 GAK62616.1 - 8.4e-17 61.1 15.5 8.4e-17 61.1 15.5 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAK62616.1 - 6.7e-09 35.4 0.0 1.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UBA_4 PF14555.6 GAK62616.1 - 0.037 13.9 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain Med3 PF11593.8 GAK62616.1 - 1.9 7.6 5.2 4.7 6.3 5.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SET PF00856.28 GAK62617.1 - 0.001 19.5 0.0 0.39 11.1 0.0 3.0 1 1 2 3 3 3 1 SET domain SDA1 PF05285.12 GAK62617.1 - 3 7.2 20.0 4.8 6.5 20.0 1.2 1 0 0 1 1 1 0 SDA1 CTU2 PF10288.9 GAK62617.1 - 9 6.6 6.9 0.75 10.1 1.0 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Ribonuc_L-PSP PF01042.21 GAK62618.1 - 5.8e-38 129.6 0.1 9.7e-38 128.9 0.1 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP Asp PF00026.23 GAK62619.1 - 1.9e-45 155.7 14.1 1e-44 153.2 14.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK62619.1 - 4.5e-06 27.0 8.5 0.022 15.0 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAK62619.1 - 2.1e-05 25.1 1.7 0.1 13.2 0.5 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAK62619.1 - 3e-05 24.5 0.4 0.048 14.2 0.1 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 GAK62619.1 - 0.0029 17.4 0.0 0.0078 16.0 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal MGC-24 PF05283.11 GAK62620.1 - 0.0046 17.4 8.3 0.0046 17.4 8.3 2.3 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 GAK62620.1 - 0.096 13.6 0.0 0.2 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Beta-APP PF03494.13 GAK62620.1 - 0.26 11.2 3.0 0.47 10.3 3.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Sugar_tr PF00083.24 GAK62621.1 - 2.4e-121 405.8 25.4 2.8e-121 405.6 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK62621.1 - 1.8e-25 89.6 44.0 8.4e-22 77.6 9.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Imm_superinfect PF14373.6 GAK62621.1 - 0.21 11.6 4.4 13 5.8 0.1 2.8 2 0 0 2 2 2 0 Superinfection immunity protein Rhodanese PF00581.20 GAK62622.1 - 1.8e-16 60.6 0.0 5.7e-09 36.5 0.0 3.2 2 1 0 2 2 2 2 Rhodanese-like domain Polysacc_synt_4 PF04669.13 GAK62622.1 - 0.037 13.6 0.0 0.083 12.4 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis ThiC-associated PF13667.6 GAK62622.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ThiC-associated domain MFS_1 PF07690.16 GAK62623.1 - 2.8e-26 92.3 27.0 2.8e-26 92.3 27.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAK62623.1 - 0.00012 21.5 5.9 0.00012 21.5 5.9 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB HIG_1_N PF04588.13 GAK62625.1 - 1.3e-16 60.5 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Aa_trans PF01490.18 GAK62626.1 - 6e-53 180.0 39.0 6.8e-53 179.8 39.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EI24 PF07264.11 GAK62627.1 - 3.1e-29 102.5 8.7 4.4e-29 102.0 8.7 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Yeast-kill-tox PF09207.11 GAK62628.1 - 0.084 13.5 2.7 2.4 8.9 0.3 2.8 3 0 0 3 3 3 0 Yeast killer toxin DHquinase_II PF01220.19 GAK62629.1 - 2.9e-64 214.9 0.0 3.4e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II ALO PF04030.14 GAK62630.1 - 1.6e-63 215.0 3.7 2.2e-54 185.0 0.7 3.0 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 GAK62630.1 - 5.8e-18 65.0 0.8 1.1e-17 64.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain EphA2_TM PF14575.6 GAK62631.1 - 0.0056 17.5 0.0 0.0077 17.1 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.12 GAK62631.1 - 0.019 15.1 0.6 0.034 14.3 0.2 1.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) MacB_PCD PF12704.7 GAK62631.1 - 0.021 15.2 0.0 0.025 15.0 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain ASFV_J13L PF05568.11 GAK62631.1 - 0.023 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2275 PF10039.9 GAK62631.1 - 0.039 14.0 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF3309 PF11752.8 GAK62631.1 - 0.044 13.8 1.7 0.094 12.8 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Glyco_transf_56 PF07429.11 GAK62631.1 - 0.063 12.4 0.1 0.075 12.1 0.1 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 SKG6 PF08693.10 GAK62631.1 - 0.093 12.2 5.2 0.16 11.4 5.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sec66 PF09802.9 GAK62631.1 - 0.23 11.0 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 SUR7 PF06687.12 GAK62632.1 - 6.2e-10 39.1 6.7 8.4e-10 38.6 6.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3767 PF12597.8 GAK62633.1 - 4.4e-25 87.4 0.2 5.6e-25 87.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF2076 PF09849.9 GAK62633.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_11 PF13414.6 GAK62634.1 - 3.9e-18 64.9 8.9 8.3e-06 25.4 0.2 4.5 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.28 GAK62634.1 - 3.9e-18 64.4 6.4 3.6e-06 26.5 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAK62634.1 - 3.1e-17 61.2 7.6 1e-06 28.4 0.1 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAK62634.1 - 8.8e-13 48.7 4.1 2.5e-07 31.2 0.2 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAK62634.1 - 1e-12 48.1 9.8 8.8e-05 22.7 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAK62634.1 - 9.5e-11 42.1 7.3 6e-05 23.5 0.5 3.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK62634.1 - 9.6e-11 41.6 8.0 0.0064 17.2 0.1 4.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAK62634.1 - 2.1e-10 40.0 4.2 0.019 15.1 0.1 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAK62634.1 - 7.7e-10 38.5 6.2 0.058 13.8 0.1 4.9 5 1 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAK62634.1 - 1.7e-06 27.6 6.6 1.2 9.3 0.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAK62634.1 - 2.5e-06 27.7 3.2 0.03 14.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAK62634.1 - 8.6e-05 22.6 1.1 0.0095 16.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK62634.1 - 0.00012 22.3 1.8 0.059 13.6 0.7 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 GAK62634.1 - 0.0074 16.6 5.4 0.021 15.1 0.3 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAK62634.1 - 0.03 14.2 9.8 1.6 8.7 1.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat SLATT_3 PF18184.1 GAK62634.1 - 0.52 10.5 5.0 1.6 8.9 5.0 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 HSCB_C PF07743.13 GAK62634.1 - 3.7 8.1 7.7 0.89 10.1 1.8 2.7 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2034 PF10356.9 GAK62635.1 - 2.8e-15 56.2 1.0 7.7e-09 35.2 0.1 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 GAK62635.1 - 5.8e-07 29.5 0.0 6.4e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease Oxidored_FMN PF00724.20 GAK62636.1 - 4.2e-53 180.8 0.0 1.3e-52 179.2 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N PF00107.26 GAK62637.1 - 5.7e-31 107.2 0.8 8.5e-31 106.6 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK62637.1 - 3.9e-12 47.4 0.0 6.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK62637.1 - 9.2e-05 22.3 0.0 0.00023 21.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAK62637.1 - 0.00061 19.2 0.9 0.00096 18.5 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Acetyltransf_8 PF13523.6 GAK62638.1 - 1.8e-35 121.8 0.2 3.3e-35 120.9 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 GAK62639.1 - 0.0041 17.2 7.0 0.0075 16.4 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBZ_FAAP20 PF15750.5 GAK62639.1 - 1.3 9.0 5.3 17 5.5 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger SDH_alpha PF03313.15 GAK62640.1 - 9.8e-96 320.4 0.4 1.4e-95 319.9 0.4 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 GAK62640.1 - 2.9e-54 183.7 0.1 1.1e-53 181.8 0.0 1.9 2 0 0 2 2 2 1 Serine dehydratase beta chain zf-C3HC4 PF00097.25 GAK62641.1 - 8e-05 22.4 1.0 0.00019 21.2 1.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAK62641.1 - 0.0012 19.1 7.2 0.0026 18.0 7.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAK62641.1 - 0.0021 18.4 5.5 0.0021 18.4 5.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAK62641.1 - 0.013 15.5 2.4 0.028 14.4 2.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAK62641.1 - 0.02 14.7 8.6 0.037 13.9 4.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAK62641.1 - 0.32 11.1 3.8 0.46 10.6 1.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAK62641.1 - 0.86 9.3 3.6 1.9 8.2 3.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DnaJ PF00226.31 GAK62642.1 - 5.6e-15 55.2 1.5 1.2e-14 54.2 1.5 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2924 PF11149.8 GAK62642.1 - 0.28 11.5 3.7 0.55 10.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) DUF2635 PF10948.8 GAK62643.1 - 0.18 11.6 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) PolC_DP2 PF03833.13 GAK62643.1 - 0.32 8.8 0.8 0.43 8.4 0.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TAL_FSA PF00923.19 GAK62644.1 - 8.9e-46 156.5 0.1 1.4e-45 155.9 0.1 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pyr_redox_2 PF07992.14 GAK62645.1 - 3.2e-50 171.0 7.0 4e-50 170.7 7.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 GAK62645.1 - 1.3e-15 57.1 0.0 2.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 GAK62645.1 - 2.8e-12 46.5 1.1 1.6e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK62645.1 - 5.4e-12 46.1 9.8 2.2e-10 41.0 1.2 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAK62645.1 - 5e-05 22.6 1.1 0.42 9.7 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.6 GAK62645.1 - 9.5e-05 22.9 0.0 0.0041 17.7 0.0 2.6 2 0 0 2 2 2 1 Reductase C-terminal GIDA PF01134.22 GAK62645.1 - 0.00087 18.5 1.3 0.025 13.7 0.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Rieske_2 PF13806.6 GAK62645.1 - 0.0051 16.7 0.0 0.038 13.9 0.0 2.5 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 GAK62645.1 - 0.016 15.2 2.9 0.14 12.2 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 GAK62645.1 - 0.033 14.6 5.9 0.21 12.0 0.4 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 GAK62645.1 - 0.077 13.2 2.2 2.9 8.2 0.2 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 GAK62645.1 - 0.082 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) DUF1344 PF07076.11 GAK62645.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DAO PF01266.24 GAK62645.1 - 0.19 11.3 4.0 2.3 7.7 0.1 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase Eno-Rase_NADH_b PF12242.8 GAK62645.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.0 2 0 0 2 2 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_2 PF00890.24 GAK62645.1 - 0.29 10.2 8.2 5.6 5.9 0.5 3.5 3 1 0 3 3 3 0 FAD binding domain TrkA_N PF02254.18 GAK62645.1 - 0.46 10.7 4.6 3.6 7.9 0.4 2.8 3 0 0 3 3 3 0 TrkA-N domain HI0933_like PF03486.14 GAK62645.1 - 0.67 8.6 5.6 0.75 8.4 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Sdh5 PF03937.16 GAK62647.1 - 1.5e-26 92.2 0.5 2.2e-26 91.6 0.5 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase MSA-2c PF12238.8 GAK62647.1 - 2.9 7.9 5.9 4.7 7.2 5.9 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.16 GAK62648.1 - 1.7e-38 132.4 47.8 1.7e-38 132.4 47.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK62648.1 - 3.8e-09 35.9 11.7 3.8e-09 35.9 11.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.18 GAK62649.1 - 1e-05 25.5 7.5 1.8e-05 24.7 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK62649.1 - 0.00017 20.7 3.1 0.0028 16.7 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain BPS1 PF05633.11 GAK62649.1 - 0.06 12.3 1.4 0.12 11.3 1.4 1.4 1 0 0 1 1 1 0 Protein BYPASS1-related PQ-loop PF04193.14 GAK62651.1 - 3e-16 58.9 22.4 9.1e-09 35.0 6.0 3.6 4 0 0 4 4 4 2 PQ loop repeat DUF2207 PF09972.9 GAK62651.1 - 0.007 15.2 0.2 0.019 13.8 0.0 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) SPX PF03105.19 GAK62651.1 - 1.2 8.9 8.6 1.7 8.5 8.6 1.1 1 0 0 1 1 1 0 SPX domain Syndecan PF01034.20 GAK62651.1 - 1.8 8.5 4.5 15 5.6 0.2 2.7 2 0 0 2 2 2 0 Syndecan domain Pro_dh PF01619.18 GAK62652.1 - 1.4e-48 165.9 0.0 7.3e-23 81.5 0.0 3.1 3 0 0 3 3 3 3 Proline dehydrogenase DUF2138 PF09909.9 GAK62653.1 - 0.11 10.7 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) MIOX PF05153.15 GAK62654.1 - 1.4e-120 401.5 0.4 1.7e-120 401.2 0.4 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 GAK62654.1 - 0.002 18.3 0.4 1.2 9.4 0.0 2.8 3 0 0 3 3 3 2 HD domain zf-DNL PF05180.12 GAK62655.1 - 3.9e-30 103.6 0.3 6e-30 103.0 0.3 1.3 1 0 0 1 1 1 1 DNL zinc finger DUF4097 PF13349.6 GAK62655.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative adhesin Amidase PF01425.21 GAK62656.1 - 2.4e-94 316.8 0.0 4e-94 316.1 0.0 1.3 1 1 0 1 1 1 1 Amidase AAA_16 PF13191.6 GAK62657.1 - 0.00024 21.5 0.6 0.011 16.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAK62657.1 - 0.021 15.1 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.12 GAK62657.1 - 0.036 13.8 2.8 0.076 12.7 2.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PaaA_PaaC PF05138.12 GAK62657.1 - 0.083 12.0 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DUF4611 PF15387.6 GAK62657.1 - 1.7 8.9 6.3 5.7 7.2 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.11 GAK62657.1 - 3.7 5.5 6.2 19 3.1 3.6 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 GAK62657.1 - 6.6 7.2 8.4 4.3 7.8 5.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pre-PUA PF17832.1 GAK62658.1 - 1.1e-24 87.0 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 GAK62658.1 - 4.6e-20 71.4 0.2 6.8e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 PUA domain SQS_PSY PF00494.19 GAK62659.1 - 1.3e-57 195.4 0.2 2e-57 194.7 0.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase PTPLA PF04387.14 GAK62660.1 - 3.5e-54 183.0 7.6 3.5e-54 183.0 7.6 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA HlyIII PF03006.20 GAK62661.1 - 1.7e-50 171.8 13.9 2.3e-50 171.4 13.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.18 GAK62661.1 - 4.4 7.1 8.3 1.5 8.7 3.5 2.3 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain p450 PF00067.22 GAK62662.1 - 4e-82 276.4 0.0 4.8e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BtrH_N PF14399.6 GAK62662.1 - 0.039 14.2 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal GDPD PF03009.17 GAK62663.1 - 1.1e-30 107.2 0.0 1.9e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 GAK62663.1 - 0.0046 17.4 0.6 0.0046 17.4 0.6 2.5 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family AFG1_ATPase PF03969.16 GAK62665.1 - 7.3e-91 304.7 0.0 1.4e-88 297.2 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 GAK62665.1 - 1.5e-07 32.0 0.0 4.6e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAK62665.1 - 2.2e-05 24.8 0.0 0.00018 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAK62665.1 - 0.0013 19.1 0.1 0.012 16.1 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAK62665.1 - 0.065 13.6 0.0 0.52 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 GAK62665.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyoxalase PF00903.25 GAK62666.1 - 0.0007 19.8 0.0 0.0097 16.1 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 GAK62666.1 - 0.0017 18.3 0.0 0.22 11.5 0.0 2.9 2 1 0 3 3 3 1 Glyoxalase-like domain MFS_1 PF07690.16 GAK62667.1 - 2.5e-31 108.9 28.6 1e-30 106.9 29.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4574 PF15141.6 GAK62667.1 - 0.19 11.7 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Abhydrolase_6 PF12697.7 GAK62668.1 - 3.1e-26 93.4 4.3 3.1e-26 93.4 4.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK62668.1 - 1.5e-10 40.7 0.2 2.5e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAK62668.1 - 2.3e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 GAK62668.1 - 0.00021 21.0 0.1 0.00078 19.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 GAK62668.1 - 0.0056 16.2 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 GAK62668.1 - 0.0079 15.9 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 GAK62668.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 GAK62668.1 - 0.068 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 GAK62668.1 - 0.15 11.6 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 GAK62669.1 - 1.7e-35 122.8 0.1 2.3e-35 122.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 GAK62669.1 - 0.00076 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 GAK62669.1 - 0.082 12.7 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TED_complement PF07678.14 GAK62669.1 - 0.13 11.2 0.2 0.19 10.7 0.2 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain DUF2974 PF11187.8 GAK62669.1 - 0.13 11.8 0.2 0.23 11.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Sugar_tr PF00083.24 GAK62670.1 - 1.7e-51 175.6 17.8 2.2e-51 175.2 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK62670.1 - 3e-26 92.2 31.2 1.8e-14 53.5 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAK62670.1 - 0.00047 19.6 4.3 0.00047 19.6 4.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TPMT PF05724.11 GAK62673.1 - 3.7e-29 101.9 0.0 1.6e-26 93.3 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 GAK62673.1 - 1.1e-06 29.2 0.0 1.8e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK62673.1 - 5.5e-06 26.3 0.0 8.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK62673.1 - 6.7e-06 26.7 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK62673.1 - 0.00032 21.4 0.0 0.00055 20.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK62673.1 - 0.00093 19.1 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_92 PF07971.12 GAK62674.1 - 1.6e-112 376.8 0.0 2.2e-112 376.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAK62674.1 - 2.8e-38 132.1 0.0 4.6e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF2540 PF10802.8 GAK62675.1 - 0.00078 19.5 0.5 0.0015 18.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2540) Oxidored_FMN PF00724.20 GAK62678.1 - 1.3e-37 129.9 0.0 1.8e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.25 GAK62679.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK62679.1 - 0.0038 17.6 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK62679.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein adh_short PF00106.25 GAK62680.1 - 6.7e-40 136.6 0.1 8.9e-40 136.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK62680.1 - 1.3e-27 96.8 0.1 1.8e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK62680.1 - 4.1e-12 46.4 1.3 6.5e-12 45.7 1.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAK62680.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAK62680.1 - 0.062 12.7 0.3 0.16 11.3 0.2 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GAK62680.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAK62680.1 - 0.08 12.3 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glutaredoxin PF00462.24 GAK62680.1 - 0.16 12.2 0.0 2.2 8.6 0.0 2.6 2 1 1 3 3 3 0 Glutaredoxin LOR PF04525.12 GAK62682.1 - 1.3e-18 67.2 0.0 1.6e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related DUF1295 PF06966.12 GAK62683.1 - 1.6e-51 175.1 0.2 2.5e-51 174.5 0.1 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 GAK62683.1 - 5.5e-06 26.7 0.0 2.4e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 GAK62683.1 - 0.0002 21.4 0.1 0.00043 20.3 0.0 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 GAK62683.1 - 0.011 16.1 0.5 0.036 14.4 0.0 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase Choline_transpo PF04515.12 GAK62684.1 - 8.6e-72 242.1 29.5 8.6e-72 242.1 29.5 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter AMP-binding PF00501.28 GAK62685.1 - 2.1e-66 224.3 0.0 2.4e-64 217.5 0.0 2.4 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 GAK62685.1 - 3e-05 24.9 0.0 0.00014 22.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TetR_C_11 PF16859.5 GAK62685.1 - 0.0037 17.6 2.0 0.0054 17.0 0.2 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Fungal_trans_2 PF11951.8 GAK62687.1 - 1.8e-18 66.5 0.4 3.9e-17 62.1 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62687.1 - 3.3e-05 23.9 12.7 6.2e-05 23.0 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BLM10_N PF16547.5 GAK62687.1 - 0.12 12.7 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal FAM153 PF15722.5 GAK62687.1 - 0.57 10.5 4.0 0.95 9.8 0.7 2.4 2 0 0 2 2 2 0 FAM153 family DnaJ_C PF01556.18 GAK62688.1 - 2.4e-25 89.3 0.0 4.2e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAK62688.1 - 2.8e-21 75.4 4.1 5.2e-21 74.5 4.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAK62688.1 - 9.2e-15 54.8 13.4 1.5e-14 54.1 13.4 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAK62688.1 - 0.00023 21.1 6.6 0.15 12.1 0.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAK62688.1 - 0.004 17.1 3.8 1.5 8.9 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 GAK62688.1 - 0.11 12.2 0.2 0.11 12.2 0.2 3.4 3 1 1 4 4 4 0 A2L zinc ribbon domain Lar_restr_allev PF14354.6 GAK62688.1 - 2.8 8.4 5.3 5.4 7.5 3.1 2.5 2 1 1 3 3 3 0 Restriction alleviation protein Lar C1_2 PF03107.16 GAK62688.1 - 6.6 7.1 6.7 9.3 6.7 0.7 2.4 2 0 0 2 2 2 0 C1 domain Indigoidine_A PF04227.12 GAK62689.1 - 1.5e-113 379.0 0.4 2.3e-113 378.4 0.4 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 GAK62689.1 - 2.1e-21 76.5 1.3 2e-12 47.0 0.6 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase AP_endonuc_2 PF01261.24 GAK62690.1 - 1.9e-18 66.7 0.1 1.4e-13 50.8 0.0 3.0 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel FKBP_C PF00254.28 GAK62691.1 - 9.1e-30 102.8 0.1 3.7e-29 100.9 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 GAK62691.1 - 4.3e-17 62.6 0.1 4.3e-17 62.6 0.1 2.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 GAK62691.1 - 0.0033 17.6 16.4 0.0033 17.6 16.4 2.2 2 0 0 2 2 2 1 YL1 nuclear protein GREB1 PF15782.5 GAK62691.1 - 4.5 4.2 6.4 5 4.1 6.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 GAK62691.1 - 8.3 5.0 9.1 11 4.6 9.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2981 PF11200.8 GAK62691.1 - 8.3 6.0 9.9 12 5.5 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Hydrolase_4 PF12146.8 GAK62693.1 - 9.6e-09 34.8 1.1 2.8e-06 26.8 0.5 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAK62693.1 - 6.1e-08 32.4 0.0 9.5e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAK62693.1 - 5.7e-07 29.4 0.5 0.00024 20.8 0.4 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.10 GAK62693.1 - 2.4e-05 23.6 0.0 4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF915 PF06028.11 GAK62693.1 - 0.062 12.6 0.0 0.78 9.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) CoA_transf_3 PF02515.17 GAK62694.1 - 1.1e-43 149.8 0.0 8.9e-36 123.8 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III MFS_1 PF07690.16 GAK62695.1 - 3.2e-39 134.8 41.8 3.2e-39 134.8 41.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK62695.1 - 1.9e-09 36.9 12.2 1.9e-09 36.9 12.2 2.4 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAK62695.1 - 0.00016 20.7 0.5 0.00016 20.7 0.5 2.1 1 1 1 2 2 2 1 MFS_1 like family DUF1129 PF06570.11 GAK62695.1 - 0.015 14.8 6.5 0.077 12.5 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Rrp15p PF07890.12 GAK62696.1 - 0.00044 20.6 2.7 0.00056 20.3 2.7 1.3 1 0 0 1 1 1 1 Rrp15p Carboxyl_trans PF01039.22 GAK62697.1 - 1.4e-105 353.8 0.0 1.8e-105 353.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Myb_DNA-binding PF00249.31 GAK62698.1 - 6.6e-30 103.1 6.3 9.4e-13 48.1 0.1 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAK62698.1 - 4.3e-26 90.9 0.2 3e-10 40.2 0.0 3.6 2 2 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 GAK62698.1 - 0.00043 20.3 2.3 0.79 9.9 0.1 3.1 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 GAK62698.1 - 0.0057 16.9 1.3 5.4 7.4 0.1 3.2 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 GAK62698.1 - 0.066 13.6 4.7 1.5 9.3 0.2 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 GAK62698.1 - 0.083 12.9 0.0 3.9 7.5 0.0 2.6 2 1 0 2 2 2 0 SLIDE DEAD PF00270.29 GAK62699.1 - 2.4e-20 73.1 0.0 4.9e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK62699.1 - 0.00014 22.2 0.0 0.00031 21.1 0.0 1.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Fe-S_biosyn PF01521.20 GAK62700.1 - 3.3e-17 62.7 0.0 4.5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis AAA PF00004.29 GAK62701.1 - 1e-43 148.9 0.0 2.1e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK62701.1 - 3.5e-10 39.5 0.1 8.2e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAK62701.1 - 3.5e-08 33.3 1.8 8e-08 32.1 1.8 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 GAK62701.1 - 1.6e-07 31.6 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAK62701.1 - 4.1e-06 26.9 0.0 1.6e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAK62701.1 - 5e-06 27.0 0.1 6.8e-05 23.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAK62701.1 - 1.6e-05 25.2 0.3 0.005 17.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAK62701.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAK62701.1 - 0.0013 19.2 0.1 0.018 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 GAK62701.1 - 0.0014 18.0 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GAK62701.1 - 0.0017 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAK62701.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 GAK62701.1 - 0.0054 16.2 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF2072 PF09845.9 GAK62701.1 - 0.0076 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Zn-ribbon containing protein AAA_24 PF13479.6 GAK62701.1 - 0.0079 15.9 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAK62701.1 - 0.0089 15.4 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAK62701.1 - 0.0091 16.3 0.2 0.022 15.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 GAK62701.1 - 0.0092 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 GAK62701.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 GAK62701.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 GAK62701.1 - 0.029 14.1 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 GAK62701.1 - 0.032 13.4 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAK62701.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAK62701.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 GAK62701.1 - 0.052 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAK62701.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TMF_TATA_bd PF12325.8 GAK62701.1 - 0.065 13.5 1.0 0.1 12.8 0.2 1.7 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding AAA_11 PF13086.6 GAK62701.1 - 0.068 12.9 0.1 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAK62701.1 - 0.069 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RILP PF11461.8 GAK62701.1 - 0.082 13.1 1.0 0.16 12.2 1.0 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein Zeta_toxin PF06414.12 GAK62701.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 GAK62701.1 - 0.13 12.5 0.4 0.49 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain PRAP PF15314.6 GAK62702.1 - 0.096 13.2 2.8 0.31 11.5 2.8 1.9 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine Mak10 PF04112.13 GAK62703.1 - 3.3e-58 195.9 0.0 7.3e-58 194.8 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Alpha-L-AF_C PF06964.12 GAK62704.1 - 2.8e-27 95.9 0.1 5.9e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 GAK62704.1 - 2.1e-06 28.1 0.4 4.9e-06 26.8 0.4 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain Ferric_reduct PF01794.19 GAK62705.1 - 2.4e-22 79.4 15.2 5.5e-22 78.2 13.7 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAK62705.1 - 8.1e-12 45.5 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAK62705.1 - 2.1e-06 27.8 0.0 4.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain MFS_1 PF07690.16 GAK62706.1 - 4.6e-13 48.8 34.1 7.6e-09 35.0 4.7 4.2 2 1 1 3 3 3 2 Major Facilitator Superfamily NAD_binding_6 PF08030.12 GAK62706.1 - 5.8e-08 33.0 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAK62706.1 - 1.3e-06 28.6 5.3 1.3e-06 28.6 5.3 3.8 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAK62706.1 - 4e-05 23.7 0.0 8.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Sugar_tr PF00083.24 GAK62706.1 - 0.0001 21.3 10.0 0.0062 15.4 0.0 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 GAK62706.1 - 0.023 13.0 6.5 0.0036 15.7 2.4 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAK62707.1 - 1.5e-10 40.6 0.5 2.2e-10 40.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK62707.1 - 1.6e-06 28.2 9.7 2.7e-06 27.4 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAK62708.1 - 1.5e-37 129.4 47.7 1.5e-37 129.4 47.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAK62708.1 - 1.3e-11 43.7 21.4 2.7e-11 42.6 21.4 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Complex1_LYR PF05347.15 GAK62709.1 - 2.4e-11 43.5 1.3 3.5e-11 43.0 1.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAK62709.1 - 0.019 15.7 0.1 0.028 15.1 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like DUF1155 PF06633.11 GAK62710.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) DUF2417 PF10329.9 GAK62710.1 - 0.58 9.5 2.8 1.2 8.5 2.8 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF3742 PF12553.8 GAK62710.1 - 2.4 8.3 6.6 15 5.7 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3742) Herpes_LMP1 PF05297.11 GAK62710.1 - 6.6 5.8 11.7 0.44 9.7 4.6 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) SH3_9 PF14604.6 GAK62711.1 - 1.9e-21 75.6 0.3 4.6e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAK62711.1 - 1.3e-17 63.1 0.0 4.5e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAK62711.1 - 1.6e-14 53.3 0.0 1.6e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 GAK62711.1 - 2.4e-12 46.9 1.5 6.6e-12 45.5 0.2 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 GAK62711.1 - 3.1e-12 46.2 3.6 6.3e-12 45.2 3.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 GAK62711.1 - 0.073 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Mod_r PF07200.13 GAK62711.1 - 0.11 12.6 8.5 0.54 10.3 0.7 3.6 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein FHA PF00498.26 GAK62712.1 - 2.9e-15 56.3 0.1 6.9e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAK62712.1 - 0.00066 20.0 0.0 0.027 14.8 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LAP1C PF05609.12 GAK62712.1 - 0.6 9.1 11.9 0.69 8.9 11.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 GAK62712.1 - 0.87 8.1 13.8 0.89 8.0 13.8 1.1 1 0 0 1 1 1 0 Macoilin family Fer2_3 PF13085.6 GAK62713.1 - 8.9e-32 109.3 0.0 1.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAK62713.1 - 2.7e-09 37.4 7.3 2.7e-09 37.4 7.3 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAK62713.1 - 3.8e-07 30.5 8.0 3.8e-07 30.5 8.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAK62713.1 - 4.9e-06 26.6 3.6 4.9e-06 26.6 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAK62713.1 - 0.0019 18.8 6.1 0.0019 18.8 6.1 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAK62713.1 - 0.0081 16.1 0.5 0.0081 16.1 0.5 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 GAK62713.1 - 0.77 10.0 13.4 0.34 11.1 8.8 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Metallophos PF00149.28 GAK62714.1 - 6.3e-18 66.0 0.2 1.4e-17 64.9 0.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAK62714.1 - 4.8e-16 59.4 0.3 1.2e-15 58.1 0.3 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAK62714.1 - 2.1e-15 57.0 0.4 4.1e-15 56.1 0.4 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 GAK62714.1 - 0.0027 17.9 0.0 0.04 14.1 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 GAK62714.1 - 0.075 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain CAP59_mtransfer PF11735.8 GAK62715.1 - 2.1e-76 256.8 0.1 2.8e-76 256.4 0.1 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MARVEL PF01284.23 GAK62715.1 - 0.073 13.1 5.3 0.17 11.9 5.3 1.5 1 0 0 1 1 1 0 Membrane-associating domain Glyco_tranf_2_4 PF13704.6 GAK62715.1 - 0.081 13.5 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 CMAS PF02353.20 GAK62716.1 - 4.9e-65 219.5 0.0 5e-53 180.2 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 GAK62716.1 - 4.7e-10 40.0 0.0 1.4e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK62716.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK62716.1 - 2.6e-08 34.4 0.0 5.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK62716.1 - 9.5e-07 28.7 0.0 2.3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 GAK62716.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 GAK62716.1 - 0.014 16.2 0.0 0.03 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 GAK62716.1 - 0.073 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PCI PF01399.27 GAK62719.1 - 3.1e-08 34.1 0.0 8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain SUIM_assoc PF16619.5 GAK62719.1 - 7.2e-05 22.8 1.7 0.00016 21.7 1.7 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RAB3GAP2_N PF14655.6 GAK62719.1 - 0.014 14.7 0.7 0.024 13.9 0.7 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RCR PF12273.8 GAK62719.1 - 0.015 16.0 0.4 0.028 15.1 0.4 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Spt20 PF12090.8 GAK62719.1 - 0.019 14.6 12.8 0.033 13.8 12.8 1.3 1 0 0 1 1 1 0 Spt20 family LETM1 PF07766.13 GAK62719.1 - 0.036 13.4 0.4 0.077 12.3 0.4 1.5 1 0 0 1 1 1 0 LETM1-like protein EPL1 PF10513.9 GAK62719.1 - 0.53 10.7 4.7 0.19 12.1 1.8 1.6 2 0 0 2 2 2 0 Enhancer of polycomb-like SmAKAP PF15127.6 GAK62719.1 - 0.6 11.3 4.3 0.25 12.5 1.4 1.8 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein DUF4834 PF16118.5 GAK62719.1 - 6.1 7.9 6.7 2.5 9.1 4.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TOBE_3 PF12857.7 GAK62720.1 - 0.17 11.8 1.1 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 TOBE-like domain LapA_dom PF06305.11 GAK62721.1 - 0.034 13.9 0.6 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain VCBS PF13517.6 GAK62721.1 - 0.046 14.3 2.2 3.2 8.4 0.4 3.0 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Syndecan PF01034.20 GAK62721.1 - 0.16 11.9 0.3 0.33 10.9 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 GAK62721.1 - 0.94 9.5 3.2 3.3 7.7 3.2 2.1 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Tmemb_14 PF03647.13 GAK62722.1 - 8.8e-22 77.7 6.4 1.3e-21 77.1 6.4 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C NPV_P10 PF05531.12 GAK62723.1 - 0.2 12.1 10.3 7.1 7.2 3.5 4.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TraF_2 PF13729.6 GAK62723.1 - 1 8.7 13.8 6.9 5.9 0.1 3.4 2 2 1 3 3 3 0 F plasmid transfer operon, TraF, protein LUC7 PF03194.15 GAK62723.1 - 6.6 6.3 29.9 2.9 7.5 10.2 3.3 1 1 2 3 3 3 0 LUC7 N_terminus UPF0184 PF03670.13 GAK62723.1 - 7.7 7.0 11.7 49 4.4 5.2 4.6 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) Baculo_PEP_C PF04513.12 GAK62723.1 - 9.4 6.3 10.1 45 4.1 3.7 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_2_C PF02836.17 GAK62724.1 - 3.8e-14 52.5 0.0 6.2e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 GAK62724.1 - 4.5e-11 42.9 1.1 1.5e-10 41.2 1.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 GAK62724.1 - 3.9e-07 30.7 0.0 8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 adh_short_C2 PF13561.6 GAK62725.1 - 1.7e-54 184.8 0.2 2.6e-54 184.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK62725.1 - 3.7e-43 147.3 0.1 5e-43 146.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK62725.1 - 5.7e-10 39.4 0.4 9.1e-10 38.7 0.4 1.3 1 0 0 1 1 1 1 KR domain WD40_4 PF16300.5 GAK62726.1 - 0.065 13.1 0.0 0.78 9.7 0.0 2.1 2 0 0 2 2 2 0 Type of WD40 repeat Fer2 PF00111.27 GAK62727.1 - 1.6e-11 44.0 0.2 2.3e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ProRS-C_1 PF09180.11 GAK62728.1 - 3.2e-24 84.9 1.5 3.2e-24 84.9 1.5 1.8 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 GAK62728.1 - 6.3e-21 74.3 0.0 2e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 GAK62728.1 - 2e-18 66.7 0.4 3.5e-18 65.8 0.4 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 GAK62728.1 - 1.6e-16 60.8 0.0 3.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-CCHC PF00098.23 GAK62729.1 - 9.5e-39 129.8 51.1 1.3e-08 34.5 2.1 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 GAK62729.1 - 6.5e-08 32.4 29.6 0.46 10.5 0.1 6.1 4 2 2 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 GAK62729.1 - 0.0044 16.7 34.3 0.18 11.6 2.0 5.7 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_2 PF13696.6 GAK62729.1 - 0.081 12.8 1.3 0.081 12.8 1.3 6.3 6 0 0 6 6 6 0 Zinc knuckle zf-CCHC_5 PF14787.6 GAK62729.1 - 1.9 8.3 35.1 1.7 8.4 2.0 6.1 6 0 0 6 6 6 0 GAG-polyprotein viral zinc-finger HNH_3 PF13392.6 GAK62730.1 - 1.4 8.7 4.3 0.24 11.2 0.5 1.7 2 0 0 2 2 2 0 HNH endonuclease SKN1 PF03935.15 GAK62731.1 - 9.5e-206 684.0 1.3 1.2e-205 683.7 1.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) THOC7 PF05615.13 GAK62732.1 - 3.9e-24 85.4 9.5 3.9e-24 85.4 9.5 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 DUF4407 PF14362.6 GAK62732.1 - 0.0016 17.9 6.3 0.0038 16.6 6.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2853 PF11015.8 GAK62732.1 - 0.0024 18.5 0.6 0.08 13.6 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2853) Arfaptin PF06456.13 GAK62732.1 - 0.016 14.8 1.4 0.016 14.8 1.4 1.9 2 1 0 2 2 2 0 Arfaptin-like domain ZapB PF06005.12 GAK62732.1 - 0.018 15.5 5.6 1.7 9.1 1.2 2.7 2 0 0 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 GAK62732.1 - 0.02 14.9 6.6 0.23 11.5 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GTP-bdg_M PF16360.5 GAK62732.1 - 0.082 13.5 13.6 0.13 12.9 3.1 3.6 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region CENP-F_leu_zip PF10473.9 GAK62732.1 - 0.2 11.7 12.8 0.04 14.0 8.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 GAK62732.1 - 0.25 9.9 10.5 0.37 9.3 10.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Snapin_Pallidin PF14712.6 GAK62732.1 - 0.63 10.5 8.4 0.61 10.5 0.7 2.6 1 1 2 3 3 3 0 Snapin/Pallidin HSCB_C PF07743.13 GAK62732.1 - 0.92 10.0 6.9 3.9 8.0 0.6 2.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain V_ATPase_I PF01496.19 GAK62732.1 - 0.96 7.3 3.3 1.4 6.7 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fungal_TACC PF12709.7 GAK62732.1 - 1.4 9.4 7.2 0.41 11.1 0.9 2.6 3 0 0 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2408 PF10303.9 GAK62732.1 - 1.9 9.0 7.8 18 5.9 7.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Med21 PF11221.8 GAK62732.1 - 2 8.7 14.1 2.8 8.2 0.9 3.1 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF2205 PF10224.9 GAK62732.1 - 2 8.5 9.7 2.3 8.3 0.2 3.0 3 0 0 3 3 3 0 Short coiled-coil protein Fzo_mitofusin PF04799.13 GAK62732.1 - 2.9 7.4 7.2 6 6.4 0.2 2.2 1 1 1 2 2 2 0 fzo-like conserved region APG6_N PF17675.1 GAK62732.1 - 3.6 8.1 14.9 10 6.7 0.6 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region PIEZO PF15917.5 GAK62732.1 - 4 6.9 6.7 6.6 6.1 0.4 2.4 1 1 1 2 2 2 0 Piezo Spc24 PF08286.11 GAK62732.1 - 5.2 7.4 10.8 2.2 8.6 1.4 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 GAK62732.1 - 5.6 6.8 9.1 5.3 6.9 2.5 2.5 1 1 1 2 2 2 0 Septum formation initiator UCH PF00443.29 GAK62734.1 - 2.4e-36 125.5 0.0 1.1e-32 113.5 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK62734.1 - 0.14 11.7 0.0 3.9 7.0 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L14e PF01929.17 GAK62735.1 - 2e-31 108.3 0.9 2.8e-31 107.8 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 GAK62735.1 - 6.5e-05 22.7 0.5 0.00011 22.0 0.5 1.3 1 0 0 1 1 1 1 KOW motif Ribosomal_L44 PF00935.19 GAK62736.1 - 2.6e-34 117.5 9.6 3.8e-34 117.0 9.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 CTD PF12815.7 GAK62736.1 - 0.53 10.9 3.2 9.9 6.8 3.2 2.2 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 RAC_head PF16717.5 GAK62737.1 - 4.8e-20 72.4 8.8 4.8e-20 72.4 8.8 3.0 4 0 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 GAK62737.1 - 3.7e-18 65.4 0.1 3.7e-18 65.4 0.1 2.3 2 1 0 2 2 2 1 DnaJ domain Presenilin PF01080.17 GAK62737.1 - 4.6 5.9 8.4 7.6 5.2 8.4 1.4 1 0 0 1 1 1 0 Presenilin tRNA-synt_2b PF00587.25 GAK62738.1 - 4.4e-37 127.8 0.0 8.6e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAK62738.1 - 1.3e-20 73.6 9.9 1.3e-20 73.6 9.9 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain MIP-T3_C PF17749.1 GAK62738.1 - 0.0011 18.9 4.2 0.002 18.1 4.2 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region NuA4 PF09340.10 GAK62738.1 - 0.011 15.5 0.3 0.048 13.5 0.1 2.3 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF3829 PF12889.7 GAK62738.1 - 0.025 14.1 4.6 0.047 13.2 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF5082 PF16888.5 GAK62738.1 - 0.087 13.1 4.3 0.17 12.2 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) YPEB PF14620.6 GAK62738.1 - 0.31 10.3 7.4 0.63 9.3 7.4 1.5 1 1 0 1 1 1 0 YpeB sporulation DUF724 PF05266.14 GAK62738.1 - 0.6 9.9 9.1 0.18 11.7 5.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) CHASE3 PF05227.13 GAK62738.1 - 0.68 9.8 4.7 12 5.8 2.8 2.5 2 0 0 2 2 2 0 CHASE3 domain APG6_N PF17675.1 GAK62738.1 - 4 8.0 9.8 2.2 8.8 7.0 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 GAK62738.1 - 5.3 7.4 8.9 25 5.2 3.5 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain Glyco_hydro_8 PF01270.17 GAK62739.1 - 3.1e-20 72.3 0.0 6e-20 71.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 Ribosomal_S8 PF00410.19 GAK62740.1 - 8.3e-22 77.5 0.1 1.1e-21 77.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 GAK62741.1 - 1.2e-58 196.3 0.0 4.3e-57 191.3 0.0 2.2 2 0 0 2 2 2 2 Ribosomal S17 DNA_pol_A_exo1 PF01612.20 GAK62742.1 - 1.1e-16 61.0 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Prefoldin_2 PF01920.20 GAK62743.1 - 8e-22 77.2 14.3 9.3e-22 77.0 14.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4349 PF14257.6 GAK62743.1 - 0.0031 17.0 6.1 0.0041 16.6 6.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4349) Prefoldin_3 PF13758.6 GAK62743.1 - 0.0032 17.5 6.3 0.0043 17.1 6.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Snf7 PF03357.21 GAK62743.1 - 0.0045 16.6 3.7 0.0045 16.6 3.7 2.0 2 0 0 2 2 2 1 Snf7 Macoilin PF09726.9 GAK62743.1 - 0.018 13.6 9.1 0.02 13.5 9.1 1.0 1 0 0 1 1 1 0 Macoilin family PHM7_cyt PF14703.6 GAK62743.1 - 0.022 15.0 7.2 0.046 13.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1192 PF06698.11 GAK62743.1 - 0.036 14.1 0.9 0.036 14.1 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) BRE1 PF08647.11 GAK62743.1 - 0.048 13.7 2.2 0.048 13.7 2.2 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Turandot PF07240.11 GAK62743.1 - 0.077 13.0 1.2 0.11 12.5 0.1 1.8 2 1 1 3 3 3 0 Stress-inducible humoral factor Turandot Bcr-Abl_Oligo PF09036.10 GAK62743.1 - 0.077 13.0 0.5 0.077 13.0 0.5 1.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Fib_alpha PF08702.10 GAK62743.1 - 0.14 12.4 11.0 0.26 11.4 11.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 GAK62743.1 - 0.21 12.3 6.6 0.17 12.6 2.4 2.0 1 1 1 2 2 2 0 Occludin homology domain Rx_N PF18052.1 GAK62743.1 - 0.23 11.7 5.2 0.11 12.8 1.2 2.0 1 1 0 2 2 2 0 Rx N-terminal domain Syntaxin-6_N PF09177.11 GAK62743.1 - 0.27 11.8 5.2 0.37 11.4 5.2 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Fez1 PF06818.15 GAK62743.1 - 0.34 11.3 11.5 0.49 10.8 2.0 2.1 1 1 1 2 2 2 0 Fez1 Prefoldin PF02996.17 GAK62743.1 - 0.4 10.6 12.4 0.11 12.4 4.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit Lge1 PF11488.8 GAK62743.1 - 0.45 10.7 11.9 0.16 12.2 5.6 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Seryl_tRNA_N PF02403.22 GAK62743.1 - 0.47 10.7 11.4 0.62 10.3 11.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 GAK62743.1 - 0.56 10.4 13.7 0.35 11.0 3.5 2.2 1 1 1 2 2 2 0 Tropomyosin like UPF0242 PF06785.11 GAK62743.1 - 0.66 10.1 13.4 0.81 9.8 13.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 GAK62743.1 - 0.83 10.0 10.0 5.8 7.3 10.0 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 GAK62743.1 - 1.9 7.5 7.1 2.4 7.1 7.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin_2 PF14523.6 GAK62743.1 - 2 8.9 12.5 2.7 8.4 3.3 2.3 1 1 1 2 2 2 0 Syntaxin-like protein ADIP PF11559.8 GAK62743.1 - 2.3 8.3 12.2 0.4 10.7 3.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 GAK62743.1 - 3.5 8.3 9.6 5.4 7.7 1.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 GAK62743.1 - 4.1 7.9 8.6 2.1 8.9 3.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MIP-T3_C PF17749.1 GAK62743.1 - 4.4 7.3 13.7 0.62 10.0 5.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region ABC_tran_CTD PF16326.5 GAK62743.1 - 4.7 7.5 9.7 0.54 10.6 2.4 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 GAK62743.1 - 6.4 6.6 14.0 5.3 6.9 4.0 2.3 2 0 0 2 2 2 0 Septum formation initiator TMPIT PF07851.13 GAK62743.1 - 6.9 5.8 7.7 6.2 6.0 6.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 GAK62743.1 - 7.6 7.1 15.9 8.7 6.9 6.6 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Swi5 PF07061.11 GAK62743.1 - 8.7 6.5 10.6 9.2 6.4 1.0 2.3 1 1 0 2 2 2 0 Swi5 RNA_lig_T4_1 PF09511.10 GAK62744.1 - 3.3e-79 265.8 0.0 5e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 GAK62744.1 - 7.7e-28 97.6 0.0 6.1e-27 94.7 0.0 2.2 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 GAK62744.1 - 6.6e-20 71.9 0.0 1.1e-19 71.2 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.6 GAK62744.1 - 0.039 14.1 0.1 1.2 9.3 0.1 2.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAK62744.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3381 PF11861.8 GAK62744.1 - 7.8 6.3 14.0 14 5.5 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) AA_kinase PF00696.28 GAK62748.1 - 3.2e-38 131.7 0.2 5.5e-36 124.4 0.0 2.9 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 GAK62748.1 - 2.4e-12 46.4 0.2 3.6e-06 26.6 0.1 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 GAK62748.1 - 1.4e-09 37.6 1.3 8.9e-07 28.6 0.2 2.6 2 0 0 2 2 2 2 ACT domain SOG2 PF10428.9 GAK62749.1 - 7.9 5.6 21.6 0.12 11.5 6.6 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein WH2 PF02205.20 GAK62750.1 - 6.7e-08 32.1 1.1 1.3e-07 31.2 0.2 2.0 2 0 0 2 2 2 1 WH2 motif Cellulase PF00150.18 GAK62753.1 - 2.1e-12 47.1 7.0 1.2e-11 44.5 7.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_25 PF13649.6 GAK62754.1 - 8.1e-05 23.3 0.0 0.055 14.2 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 GAK62754.1 - 0.00018 21.0 0.1 0.00036 20.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 GAK62754.1 - 0.0018 18.1 0.0 0.0036 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 GAK62754.1 - 0.0073 16.2 0.1 0.029 14.2 0.1 1.9 1 1 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_32 PF13679.6 GAK62754.1 - 0.01 15.8 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAK62754.1 - 0.029 13.9 0.1 0.067 12.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 GAK62754.1 - 0.037 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_11 PF08241.12 GAK62754.1 - 0.037 14.7 0.1 2.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_9 PF08003.11 GAK62754.1 - 0.041 12.8 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 GAK62754.1 - 0.23 11.1 1.0 0.34 10.5 0.4 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Bromodomain PF00439.25 GAK62755.1 - 8.1e-17 61.1 0.0 1.5e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain adh_short PF00106.25 GAK62756.1 - 1.5e-17 63.7 0.1 1.2e-11 44.4 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK62756.1 - 1.7e-09 37.6 0.1 1.3e-06 28.1 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK62756.1 - 0.00048 20.1 0.1 0.00089 19.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Dus PF01207.17 GAK62757.1 - 1.1e-69 235.0 0.0 3.5e-69 233.3 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) YTH PF04146.15 GAK62758.1 - 5.7e-61 205.3 7.5 2.8e-60 203.1 7.5 2.1 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 GAK62758.1 - 0.00041 20.1 0.0 0.72 9.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF1 PF02104.15 GAK62761.1 - 1.6e-39 135.9 0.0 3.1e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 SURF1 family DUF596 PF04591.12 GAK62761.1 - 0.025 14.7 0.0 0.074 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF596 UAA PF08449.11 GAK62762.1 - 5.1e-78 262.3 0.9 6.5e-78 262.0 0.9 1.1 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 GAK62762.1 - 0.029 13.3 0.1 0.029 13.3 0.1 1.8 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like VirB3 PF05101.13 GAK62762.1 - 0.35 11.1 2.9 3.5 7.9 0.2 3.3 2 1 1 3 3 3 0 Type IV secretory pathway, VirB3-like protein PUNUT PF16913.5 GAK62762.1 - 0.54 9.4 12.9 0.01 15.0 1.9 2.5 2 1 1 3 3 3 0 Purine nucleobase transmembrane transport EMP70 PF02990.16 GAK62762.1 - 1.4 7.5 4.5 3.5 6.2 4.5 1.6 1 1 0 1 1 1 0 Endomembrane protein 70 Metallophos PF00149.28 GAK62764.1 - 8e-06 26.5 4.4 9.7e-06 26.2 2.6 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase IPK PF03770.16 GAK62765.1 - 1.7e-50 171.6 0.0 2.5e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Kelch_6 PF13964.6 GAK62766.1 - 6.2e-10 39.0 0.3 0.042 14.2 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 GAK62766.1 - 6.2e-08 32.5 0.5 0.00014 21.8 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAK62766.1 - 2.1e-07 31.1 6.6 4.5e-06 26.8 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.6 GAK62766.1 - 4.8e-07 29.7 0.1 0.86 9.7 0.0 4.3 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAK62766.1 - 6e-06 26.0 0.2 1.1 9.3 0.0 4.7 4 1 0 4 4 4 2 Kelch motif HSA PF07529.13 GAK62766.1 - 0.37 11.2 6.2 0.86 10.0 6.2 1.6 1 0 0 1 1 1 0 HSA Chordopox_A33R PF05966.12 GAK62767.1 - 0.098 11.9 1.7 1.1 8.5 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus A33R protein AMP-binding PF00501.28 GAK62768.1 - 6.1e-82 275.5 0.0 1.9e-81 273.9 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK62768.1 - 3.8e-08 34.2 0.9 1.3e-07 32.5 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RNase_PH PF01138.21 GAK62769.1 - 5.2e-32 111.1 0.0 8.7e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAK62769.1 - 0.0015 18.5 0.0 0.0041 17.1 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 GalKase_gal_bdg PF10509.9 GAK62769.1 - 0.11 12.1 0.4 0.3 10.7 0.1 1.9 2 0 0 2 2 2 0 Galactokinase galactose-binding signature Cullin PF00888.22 GAK62770.1 - 3.6e-12 45.7 0.0 5.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Cullin family Proteasome PF00227.26 GAK62771.1 - 2.3e-32 112.0 0.0 5.9e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit DUF3712 PF12505.8 GAK62773.1 - 4.3e-100 330.7 41.0 1.1e-22 80.6 0.0 8.7 9 0 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAK62773.1 - 9.2e-05 22.9 21.8 1.5 9.4 0.1 8.1 8 0 0 8 8 8 3 Late embryogenesis abundant protein Spc7 PF08317.11 GAK62774.1 - 0.11 11.4 0.2 0.16 10.8 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Adeno_E1B_55K_N PF04623.12 GAK62775.1 - 7.4 7.3 8.7 7.1 7.4 0.0 2.7 3 0 0 3 3 3 0 Adenovirus E1B protein N-terminus Glyco_hydro_16 PF00722.21 GAK62776.1 - 2.3e-38 131.4 2.0 2.3e-38 131.4 2.0 1.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Metallophos PF00149.28 GAK62778.1 - 3.3e-35 122.5 0.1 7.8e-35 121.2 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAK62778.1 - 0.034 14.6 0.1 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DUF1647 PF07801.11 GAK62778.1 - 0.063 13.0 0.8 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF771 PF05595.11 GAK62778.1 - 0.071 13.1 0.3 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF771) GTP_EFTU_D3 PF03143.17 GAK62779.1 - 2.4e-42 143.8 0.0 3.4e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAK62779.1 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RabGAP-TBC PF00566.18 GAK62780.1 - 7.9e-50 169.5 0.0 1.2e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 GAK62780.1 - 1.1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Meth_synt_2 PF01717.18 GAK62781.1 - 1.8e-150 500.7 0.0 9.5e-143 475.3 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAK62781.1 - 6.2e-119 397.2 0.0 1.8e-112 375.9 0.1 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 GAK62781.1 - 0.00034 19.9 0.1 0.044 12.9 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 GAK62781.1 - 0.064 13.0 0.6 0.15 11.8 0.6 1.7 1 0 0 1 1 1 0 Short C-terminal domain DUF726 PF05277.12 GAK62782.1 - 1.2e-57 195.4 0.7 1.8e-57 194.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 GAK62782.1 - 0.0017 19.0 0.1 0.005 17.5 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 GAK62782.1 - 0.012 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.8 GAK62782.1 - 0.048 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 GAK62782.1 - 0.054 12.7 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 GAK62782.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ubiquitin PF00240.23 GAK62783.1 - 1.6e-19 69.4 0.1 2.3e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAK62783.1 - 3.4e-08 33.2 0.3 5.5e-08 32.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAK62783.1 - 2.7e-06 27.9 0.0 4.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA PF00627.31 GAK62783.1 - 1e-05 25.3 0.4 1e-05 25.3 0.4 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 GAK62783.1 - 0.00086 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GAK62783.1 - 0.022 14.8 0.3 1.6 8.8 0.3 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 GAK62783.1 - 0.077 13.5 0.1 0.19 12.2 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 GAK62783.1 - 0.43 10.5 11.8 5.3 7.0 11.8 2.2 1 1 0 1 1 1 0 Spore germination GerD central core domain Sld7_C PF18596.1 GAK62785.1 - 0.047 13.8 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Sld7 C-terminal domain DUF4504 PF14953.6 GAK62786.1 - 2.9e-11 43.2 0.8 4.8e-05 22.9 0.2 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) FRG1 PF06229.12 GAK62787.1 - 1e-19 71.0 3.8 3.1e-18 66.2 3.8 3.0 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 GAK62787.1 - 8.6e-05 22.7 0.0 0.00027 21.1 0.0 1.9 1 1 1 2 2 2 2 Fascin domain SPT2 PF08243.11 GAK62787.1 - 4.9 7.7 16.1 0.2 12.2 8.0 2.4 2 1 1 3 3 3 0 SPT2 chromatin protein Ribosomal_L13 PF00572.18 GAK62788.1 - 6.8e-11 42.5 0.1 7.6e-10 39.1 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L32e PF01655.18 GAK62789.1 - 1.3e-48 163.9 1.5 1.5e-48 163.7 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 CaATP_NAI PF12515.8 GAK62789.1 - 4.4 7.0 6.5 0.48 10.1 0.9 2.3 3 0 0 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain TAFII55_N PF04658.13 GAK62790.1 - 9.3e-54 181.5 0.0 2.7e-53 180.0 0.0 1.8 1 0 0 1 1 1 1 TAFII55 protein conserved region GTP_EFTU PF00009.27 GAK62791.1 - 4.6e-53 179.7 0.1 6.7e-53 179.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAK62791.1 - 1.4e-41 141.3 0.0 3e-41 140.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAK62791.1 - 2.3e-12 47.1 1.2 2.3e-12 47.1 1.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAK62791.1 - 0.0013 18.8 0.1 0.03 14.4 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.16 GAK62791.1 - 0.079 13.0 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Glyoxal_oxid_N PF07250.11 GAK62793.1 - 2.8e-41 141.3 0.9 3.3e-31 108.3 0.0 3.6 2 1 1 3 3 3 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAK62793.1 - 5.9e-26 90.6 0.1 1.1e-25 89.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Tfb4 PF03850.14 GAK62794.1 - 5.4e-73 245.9 3.3 2e-71 240.8 3.3 2.1 1 1 0 1 1 1 1 Transcription factor Tfb4 DEAD PF00270.29 GAK62795.1 - 2.9e-37 128.1 0.0 5.5e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK62795.1 - 3.1e-22 79.0 0.0 9.8e-21 74.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK62795.1 - 9.9e-08 32.2 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAK62795.1 - 0.0039 17.5 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAK62795.1 - 0.028 14.7 1.1 0.52 10.6 1.1 2.7 1 1 0 1 1 1 0 AAA domain BUD22 PF09073.10 GAK62795.1 - 0.57 9.5 25.2 1.2 8.5 25.2 1.4 1 0 0 1 1 1 0 BUD22 FAM60A PF15396.6 GAK62795.1 - 7.6 6.5 9.0 1.7 8.6 4.9 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DNA_pol3_delta2 PF13177.6 GAK62797.1 - 6.5e-10 39.0 0.1 1.3e-09 38.0 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GAK62797.1 - 5.3e-05 23.7 0.4 0.00018 22.0 0.4 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 GAK62797.1 - 0.00018 21.8 0.2 0.00075 19.9 0.0 2.1 3 0 0 3 3 3 1 Replication factor C C-terminal domain Rad17 PF03215.15 GAK62797.1 - 0.00039 20.4 0.0 0.00084 19.3 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 GAK62797.1 - 0.0077 16.6 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAK62797.1 - 0.012 15.9 0.2 0.061 13.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAK62797.1 - 0.02 14.7 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 GAK62797.1 - 0.031 14.4 0.1 0.92 9.6 0.1 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 GAK62797.1 - 0.034 14.3 0.1 0.099 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAK62797.1 - 0.086 12.6 0.2 0.21 11.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAK62797.1 - 0.093 12.5 0.1 1.2 8.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 GAK62797.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NTP_transf_2 PF01909.23 GAK62798.1 - 2.1e-05 24.7 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 GAK62798.1 - 0.00029 21.0 0.1 0.0013 18.9 0.1 2.2 1 1 0 1 1 1 1 Cid1 family poly A polymerase D5_N PF08706.11 GAK62798.1 - 0.31 11.3 1.4 17 5.7 1.0 2.6 2 0 0 2 2 2 0 D5 N terminal like SUZ PF12752.7 GAK62799.1 - 8.3e-13 48.9 2.4 8.3e-13 48.9 2.4 2.5 2 2 0 2 2 2 1 SUZ domain Mito_carr PF00153.27 GAK62800.1 - 3.7e-65 215.9 5.6 3.1e-24 84.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 GAK62800.1 - 0.087 12.0 0.1 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Fuseless bZIP_1 PF00170.21 GAK62801.1 - 1.3 9.2 15.7 3.7 7.7 15.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor Zn_clus PF00172.18 GAK62802.1 - 0.002 18.2 11.4 0.0032 17.5 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 GAK62802.1 - 0.071 13.2 5.4 0.21 11.7 5.4 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAK62802.1 - 0.58 9.7 4.7 1.1 8.8 4.7 1.4 1 0 0 1 1 1 0 Spt20 family IGR PF09597.10 GAK62805.1 - 3.5e-12 46.2 0.6 6.9e-12 45.3 0.6 1.5 1 1 0 1 1 1 1 IGR protein motif 60KD_IMP PF02096.20 GAK62806.1 - 4.4e-09 36.5 0.0 8.4e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein NEMP PF10225.9 GAK62806.1 - 0.11 12.2 0.4 2.7 7.6 0.1 2.1 2 0 0 2 2 2 0 NEMP family ResIII PF04851.15 GAK62807.1 - 1.6e-21 77.0 0.0 4.1e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAK62807.1 - 6.1e-21 74.8 0.0 1.2e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK62807.1 - 2.4e-17 63.3 0.0 2.6e-16 59.9 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAK62807.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF4808 PF16066.5 GAK62807.1 - 0.068 13.7 0.4 2.4 8.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) EF-hand_7 PF13499.6 GAK62808.1 - 1.1e-28 99.4 12.4 1.2e-14 54.5 3.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAK62808.1 - 1.3e-26 90.1 17.2 1.8e-09 36.4 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GAK62808.1 - 4.5e-24 82.3 13.5 2.6e-08 33.1 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAK62808.1 - 6.8e-17 61.1 13.6 1.1e-10 41.1 1.3 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAK62808.1 - 1.2e-12 46.8 14.1 1.3e-05 24.5 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 GAK62808.1 - 1.8e-10 41.0 1.8 0.00028 21.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAK62808.1 - 1.3e-07 31.5 3.5 0.001 19.0 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 GAK62808.1 - 0.00011 22.2 2.4 0.058 13.3 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 GAK62808.1 - 0.0057 17.0 3.3 0.43 10.9 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAK62808.1 - 0.0084 16.4 4.1 0.76 10.1 0.6 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1636 PF07845.11 GAK62808.1 - 0.026 15.0 0.0 1.4 9.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) SurA_N_2 PF13623.6 GAK62808.1 - 0.037 13.9 0.9 0.9 9.4 0.2 2.4 2 1 0 2 2 2 0 SurA N-terminal domain LTXXQ PF07813.12 GAK62808.1 - 0.05 14.3 0.4 0.35 11.6 0.1 2.2 2 0 0 2 2 2 0 LTXXQ motif family protein PhetRS_B1 PF18262.1 GAK62808.1 - 0.29 11.4 2.1 0.41 10.9 0.7 1.9 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain G-patch PF01585.23 GAK62809.1 - 1.3e-12 47.4 1.1 6.1e-12 45.2 0.7 2.5 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 GAK62809.1 - 1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 GAK62809.1 - 1.4e-05 25.1 0.9 7.3e-05 22.8 0.9 2.4 1 0 0 1 1 1 1 G-patch domain DUF4722 PF15849.5 GAK62809.1 - 0.18 11.5 1.2 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) AAA_22 PF13401.6 GAK62809.1 - 0.21 11.9 0.2 1 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SPT_ssu-like PF11779.8 GAK62810.1 - 8e-15 54.2 5.0 1.1e-14 53.8 5.0 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like AF-4 PF05110.13 GAK62810.1 - 0.0059 14.8 6.8 0.0075 14.4 6.8 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RAP1 PF07218.11 GAK62810.1 - 1.3 7.2 7.7 1.5 7.0 7.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4692 PF15763.5 GAK62810.1 - 9.9 6.6 8.4 1.7 9.1 0.1 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) PCI PF01399.27 GAK62811.1 - 3.4e-05 24.3 0.0 8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain ANAPC3 PF12895.7 GAK62811.1 - 0.13 12.5 3.4 2.3 8.5 3.5 2.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CBFD_NFYB_HMF PF00808.23 GAK62812.1 - 5.8e-15 55.3 0.8 5.8e-15 55.3 0.8 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAK62812.1 - 7.9e-05 23.0 0.2 0.00013 22.4 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HSP70 PF00012.20 GAK62813.1 - 1.2e-61 208.7 4.1 1.5e-55 188.6 0.0 2.7 2 1 0 2 2 2 2 Hsp70 protein Ras PF00071.22 GAK62813.1 - 6.3e-56 188.5 0.0 1.2e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK62813.1 - 2.6e-33 114.8 0.0 6.8e-33 113.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK62813.1 - 2.8e-14 52.9 0.2 1.1e-13 51.0 0.0 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAK62813.1 - 0.00023 20.6 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK62813.1 - 0.00076 19.5 0.0 0.0056 16.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase MreB_Mbl PF06723.13 GAK62813.1 - 0.03 13.2 0.1 0.07 11.9 0.1 1.5 1 0 0 1 1 1 0 MreB/Mbl protein AAA_16 PF13191.6 GAK62813.1 - 0.03 14.7 0.0 0.03 14.7 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain UCH PF00443.29 GAK62814.1 - 4.9e-42 144.2 0.0 1.2e-41 143.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK62814.1 - 4.4e-18 65.9 0.0 3.2e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAK62814.1 - 6.7e-12 45.6 2.2 6.7e-12 45.6 2.2 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Abhydrolase_3 PF07859.13 GAK62815.1 - 2.3e-18 66.8 0.1 8.6e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAK62815.1 - 2.6e-10 39.7 0.0 1.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 GAK62815.1 - 0.021 15.5 1.0 0.057 14.0 1.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_15 PF09445.10 GAK62816.1 - 5.5e-32 110.6 0.0 8.3e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 GAK62816.1 - 1.8e-05 24.6 0.0 2.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GAK62816.1 - 0.041 14.6 0.0 0.077 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 GAK62816.1 - 0.098 12.3 0.0 0.36 10.4 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Mo25 PF08569.11 GAK62818.1 - 1.2e-134 448.9 0.6 1.9e-134 448.2 0.6 1.3 1 1 0 1 1 1 1 Mo25-like Spore_GerQ PF09671.10 GAK62818.1 - 0.016 15.2 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) GP40 PF11025.8 GAK62818.1 - 0.11 12.2 5.5 0.19 11.5 5.5 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium SR-25 PF10500.9 GAK62818.1 - 9.2 5.8 10.7 14 5.2 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ARID PF01388.21 GAK62819.1 - 6.4e-11 42.8 0.0 1.3e-09 38.6 0.0 2.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 GAK62819.1 - 2.7e-05 23.6 0.1 2.7e-05 23.6 0.1 3.4 4 1 0 4 4 4 1 SWI/SNF-like complex subunit BAF250/Osa Peptidase_M41 PF01434.18 GAK62821.1 - 2.8e-64 216.5 0.0 5.9e-64 215.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAK62821.1 - 1.1e-42 145.5 0.0 2.7e-42 144.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK62821.1 - 1.8e-12 46.9 0.1 4.6e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 GAK62821.1 - 4.4e-10 39.9 0.0 1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 GAK62821.1 - 0.0014 19.1 0.1 0.12 12.7 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAK62821.1 - 0.0026 18.0 0.0 0.61 10.4 0.1 2.9 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAK62821.1 - 0.0031 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 GAK62821.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAK62821.1 - 0.013 15.6 0.2 0.063 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAK62821.1 - 0.017 15.1 0.5 0.063 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAK62821.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 GAK62821.1 - 5.2 6.8 9.1 6.6 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Drf_GBD PF06371.13 GAK62822.1 - 4.8e-10 39.3 0.0 4.6e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Rcd1 PF04078.13 GAK62822.1 - 0.033 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Kinesin PF00225.23 GAK62823.1 - 1.1e-111 373.0 0.0 2e-111 372.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAK62823.1 - 3.6e-27 95.1 0.0 7.4e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF3450 PF11932.8 GAK62823.1 - 0.007 15.7 2.9 0.007 15.7 2.9 5.5 3 1 2 5 5 5 1 Protein of unknown function (DUF3450) DUF4407 PF14362.6 GAK62823.1 - 0.15 11.4 73.6 0.069 12.5 1.8 5.0 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) Secretin_N PF03958.17 GAK62823.1 - 0.7 10.3 0.0 0.7 10.3 0.0 4.2 5 1 0 5 5 5 0 Bacterial type II/III secretion system short domain GATA PF00320.27 GAK62824.1 - 1.2e-12 47.2 5.9 2.5e-12 46.2 5.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 GAK62824.1 - 0.0025 18.1 0.5 0.027 14.7 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 GAK62824.1 - 0.02 15.2 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold GCD14 PF08704.10 GAK62826.1 - 3.9e-80 269.1 2.9 2.9e-44 151.6 0.4 3.2 2 1 1 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Radical_SAM PF04055.21 GAK62826.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily GCD14_N PF14801.6 GAK62826.1 - 0.12 12.3 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term RR_TM4-6 PF06459.12 GAK62826.1 - 0.63 9.8 3.0 1.6 8.5 3.1 1.6 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 Velvet PF11754.8 GAK62828.1 - 4.8e-53 180.7 2.8 1.2e-33 117.1 0.1 3.2 1 1 2 3 3 3 2 Velvet factor LSM PF01423.22 GAK62829.1 - 2.6e-19 68.7 0.5 3.3e-19 68.4 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAK62829.1 - 7.6e-06 26.0 0.2 1.3e-05 25.3 0.1 1.5 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 GAK62829.1 - 0.00032 20.8 0.2 0.00043 20.3 0.2 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain PET117 PF15786.5 GAK62830.1 - 2.1e-22 79.1 2.0 4e-22 78.3 2.0 1.5 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF3384 PF11864.8 GAK62831.1 - 7.6e-172 572.5 5.6 2.8e-160 534.4 0.8 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 GAK62831.1 - 2.7e-46 157.5 0.0 6e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 GAK62831.1 - 1.8e-36 126.0 8.2 1e-31 110.4 8.5 3.6 3 1 0 3 3 3 2 Tuberin UCR_hinge PF02320.16 GAK62832.1 - 3.8e-24 84.7 5.6 3.8e-24 84.7 5.6 1.8 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein RNA_pol_3_Rpc31 PF11705.8 GAK62832.1 - 0.014 15.7 6.1 0.018 15.3 6.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 GAK62832.1 - 0.051 14.0 14.1 0.088 13.2 14.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tim54 PF11711.8 GAK62832.1 - 0.058 12.2 1.7 0.062 12.1 1.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Enkurin PF13864.6 GAK62832.1 - 0.11 12.9 6.1 0.19 12.2 6.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding YqfQ PF14181.6 GAK62832.1 - 0.15 12.2 2.1 0.2 11.9 2.1 1.3 1 0 0 1 1 1 0 YqfQ-like protein FAM176 PF14851.6 GAK62832.1 - 0.18 11.4 4.9 0.24 11.1 4.9 1.2 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 GAK62832.1 - 0.19 11.6 7.5 0.23 11.3 7.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PAXIP1_C PF15364.6 GAK62832.1 - 0.21 11.9 7.3 0.33 11.3 7.3 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Sporozoite_P67 PF05642.11 GAK62832.1 - 0.29 9.2 2.0 0.29 9.2 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 GAK62832.1 - 0.32 9.2 8.7 0.32 9.1 8.7 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 GAK62832.1 - 0.35 10.9 4.7 0.46 10.5 4.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 GAK62832.1 - 0.48 9.8 8.7 0.59 9.5 8.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 GAK62832.1 - 0.49 10.2 6.2 0.59 9.9 6.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 GAK62832.1 - 0.73 9.0 4.4 0.86 8.8 4.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 GAK62832.1 - 1.2 7.2 11.1 1.4 6.9 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GAK62832.1 - 1.3 8.4 10.5 1.5 8.2 10.5 1.1 1 0 0 1 1 1 0 SDA1 DUF3408 PF11888.8 GAK62832.1 - 2.5 8.2 8.6 3.2 7.9 7.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Radial_spoke PF04712.12 GAK62832.1 - 3.5 6.5 11.7 4.3 6.2 11.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Astro_capsid_p PF12226.8 GAK62832.1 - 4.5 6.3 8.7 5.3 6.1 8.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 GAK62832.1 - 5.2 5.2 8.9 5.9 5.1 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Aminotran_1_2 PF00155.21 GAK62833.1 - 1.5e-52 179.0 0.0 3.4e-49 168.0 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 GAK62833.1 - 0.002 17.0 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 GAK62833.1 - 0.0059 15.9 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAK62833.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Ribosomal_L24e PF01246.20 GAK62834.1 - 7.8e-22 77.3 7.3 5.4e-19 68.2 0.2 3.2 3 0 0 3 3 3 2 Ribosomal protein L24e NAT PF04768.13 GAK62836.1 - 1.9e-48 164.3 0.0 4.3e-48 163.2 0.0 1.6 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 GAK62836.1 - 1.1e-27 97.3 0.0 2.5e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 GAK62836.1 - 7e-26 91.0 0.0 2.3e-25 89.4 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain HLH PF00010.26 GAK62836.1 - 4.2e-09 36.2 0.1 9.9e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 GAK62836.1 - 1.3e-07 31.5 1.3 0.001 19.1 0.0 2.9 1 1 1 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 DapB_N PF01113.20 GAK62836.1 - 0.1 12.7 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF659 PF04937.15 GAK62836.1 - 0.18 11.7 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) GREB1 PF15782.5 GAK62836.1 - 0.31 8.1 4.6 0.47 7.5 4.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 GAK62836.1 - 0.39 10.3 21.6 0.66 9.5 21.6 1.2 1 0 0 1 1 1 0 Spt20 family LMBR1 PF04791.16 GAK62836.1 - 0.43 9.4 0.6 0.72 8.7 0.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 GAK62836.1 - 1.7 7.4 3.2 2.5 6.8 3.2 1.2 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 GAK62836.1 - 7.7 5.3 20.4 12 4.7 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 GAK62836.1 - 8.2 6.4 11.2 18 5.3 11.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 zf-C2H2 PF00096.26 GAK62838.1 - 7.9e-10 38.7 13.2 8.1e-06 26.0 3.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK62838.1 - 1.2e-05 25.5 2.8 1.2e-05 25.5 2.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAK62838.1 - 3.1e-05 24.5 12.0 0.042 14.7 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 GAK62838.1 - 0.0031 18.1 3.8 0.091 13.4 0.5 2.4 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 GAK62838.1 - 0.032 14.5 0.6 0.072 13.4 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 GAK62838.1 - 0.29 11.3 6.2 2 8.5 1.4 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 GAK62838.1 - 9.1 6.1 9.3 7.7 6.4 1.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain CRIM PF16978.5 GAK62839.1 - 6e-41 139.9 0.0 1.3e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 GAK62839.1 - 1.2e-24 86.7 0.0 2.1e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 GAK62839.1 - 0.02 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain RA PF00788.23 GAK62839.1 - 0.068 13.8 0.1 0.72 10.5 0.0 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain SANT_DAMP1_like PF16282.5 GAK62840.1 - 6.7e-32 109.5 1.1 1.1e-31 108.8 1.1 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 GAK62840.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain RasGAP PF00616.19 GAK62841.1 - 1.2e-59 201.5 0.0 3.3e-59 200.1 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAK62841.1 - 4.9e-40 136.8 0.2 4.9e-40 136.8 0.2 2.2 3 0 0 3 3 3 1 RasGAP C-terminus YabA PF06156.13 GAK62841.1 - 0.029 15.0 2.4 4.5 8.0 0.1 3.3 2 0 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 GAK62841.1 - 5.4 7.4 8.4 6.8 7.1 0.7 3.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCP_N_terminal PF17681.1 GAK62842.1 - 4.5e-86 289.2 0.0 2.5e-85 286.8 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAK62842.1 - 3.4e-75 253.4 0.4 3.8e-74 249.9 0.0 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal ADP_ribosyl_GH PF03747.14 GAK62843.1 - 0.029 14.1 1.6 0.04 13.6 1.6 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Kin17_mid PF10357.9 GAK62845.1 - 4e-48 162.5 0.3 6.6e-48 161.8 0.3 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 GAK62845.1 - 8.8e-06 25.9 1.8 1.7e-05 25.0 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAK62845.1 - 1.3e-05 25.4 1.6 2.6e-05 24.4 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAK62845.1 - 0.01 16.2 0.6 0.029 14.7 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 GAK62845.1 - 0.019 15.2 0.3 0.019 15.2 0.3 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.25 GAK62846.1 - 1.1e-50 172.4 0.0 5.2e-48 163.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62846.1 - 6.6e-22 78.0 0.0 5.4e-19 68.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK62846.1 - 0.0015 17.4 0.2 0.0034 16.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAK62846.1 - 0.01 15.8 0.9 0.061 13.2 0.9 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GAK62846.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 GAK62846.1 - 0.042 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAK62846.1 - 0.058 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain RGS PF00615.19 GAK62847.1 - 1.5e-12 47.8 0.0 5e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain FA_desaturase PF00487.24 GAK62848.1 - 9.1e-15 55.2 27.5 9.1e-15 55.2 27.5 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAK62848.1 - 1.6e-13 50.6 0.1 3e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Axin_b-cat_bind PF08833.10 GAK62848.1 - 0.11 12.6 0.2 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Axin beta-catenin binding domain SHMT PF00464.19 GAK62850.1 - 6.4e-175 581.5 0.0 7.8e-175 581.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAK62850.1 - 0.015 14.6 0.1 0.041 13.2 0.1 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase MAPEG PF01124.18 GAK62850.1 - 0.18 11.7 0.2 0.44 10.5 0.1 1.7 2 0 0 2 2 2 0 MAPEG family SNARE_assoc PF09335.11 GAK62851.1 - 2.4e-31 108.7 6.4 1.2e-30 106.4 6.4 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein DHHA2 PF02833.14 GAK62852.1 - 1e-17 64.7 0.2 1.5e-17 64.1 0.2 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 GAK62852.1 - 4.9e-08 33.1 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 DHH family Ribonuc_2-5A PF06479.12 GAK62852.1 - 0.05 13.8 1.7 2.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A Cys_Met_Meta_PP PF01053.20 GAK62855.1 - 2.1e-138 461.0 0.0 4.7e-138 459.9 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAK62855.1 - 0.029 13.7 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3107 PF11305.8 GAK62855.1 - 0.1 12.9 0.2 3 8.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) ADK PF00406.22 GAK62856.1 - 0.00013 22.1 0.0 0.033 14.3 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase AAA_33 PF13671.6 GAK62856.1 - 0.055 13.6 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAK62856.1 - 0.075 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain YtxH PF12732.7 GAK62856.1 - 0.81 10.3 0.1 0.81 10.3 0.1 3.9 4 1 1 5 5 5 0 YtxH-like protein SIR2 PF02146.17 GAK62857.1 - 8e-58 195.3 0.0 1.5e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 GAK62857.1 - 2.3e-09 37.2 0.2 1.4e-05 24.9 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF592) HTH_Crp_2 PF13545.6 GAK62857.1 - 0.012 15.6 0.0 0.092 12.7 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain CutC PF03932.14 GAK62857.1 - 0.019 14.4 0.0 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 CutC family DUF1323 PF07037.11 GAK62857.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) Metallothio_Cad PF07846.11 GAK62857.1 - 0.13 12.4 3.9 0.22 11.7 3.9 1.3 1 0 0 1 1 1 0 Metallothionein family TPPII_N PF12583.8 GAK62857.1 - 1.9 9.1 8.0 4.4 7.9 8.0 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal NGP1NT PF08153.12 GAK62858.1 - 4.6e-47 159.4 0.0 1.1e-46 158.2 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 GAK62858.1 - 1.2e-16 60.8 0.0 6.3e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK62858.1 - 8e-06 25.5 0.2 2.8e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 GAK62858.1 - 0.00032 20.2 0.1 0.068 12.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAK62858.1 - 0.0033 17.3 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAK62858.1 - 0.81 9.7 7.4 1 9.4 0.0 3.7 4 1 1 5 5 5 0 Dynamin family NTP_transf_9 PF04248.12 GAK62859.1 - 1.3e-31 108.3 1.0 4.3e-31 106.6 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF427) DCP2 PF05026.13 GAK62859.1 - 1.1e-24 86.6 0.0 1.7e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 GAK62859.1 - 2.5e-14 53.4 0.0 5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TAL_FSA PF00923.19 GAK62859.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase zf-C3HC4 PF00097.25 GAK62860.1 - 4.7e-07 29.6 6.3 4.7e-07 29.6 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 GAK62860.1 - 4.7e-07 29.5 4.1 4.7e-07 29.5 4.1 3.2 4 0 0 4 4 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK62860.1 - 8.5e-07 28.8 13.8 7.7e-06 25.8 7.0 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-RING_2 PF13639.6 GAK62860.1 - 1.1e-05 25.7 8.2 4.1e-05 23.8 8.2 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAK62860.1 - 1.3e-05 24.9 5.6 3.4e-05 23.6 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 GAK62860.1 - 2.5e-05 23.9 5.0 2.5e-05 23.9 5.0 2.7 3 0 0 3 3 3 1 CCCH-type zinc finger zf-C3HC4_2 PF13923.6 GAK62860.1 - 0.00011 21.9 8.6 0.00047 19.9 8.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK62860.1 - 0.00024 21.0 7.6 0.00077 19.4 7.6 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK62860.1 - 0.00025 21.0 6.2 0.00077 19.4 6.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Torus PF16131.5 GAK62860.1 - 0.0023 18.6 1.0 0.018 15.8 0.1 2.3 2 0 0 2 2 2 1 Torus domain Prok-RING_4 PF14447.6 GAK62860.1 - 0.0077 16.1 5.3 0.025 14.4 5.3 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAK62860.1 - 0.012 15.7 4.1 0.033 14.4 4.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 GAK62860.1 - 0.018 15.2 4.9 0.066 13.4 4.9 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-CCCH_2 PF14608.6 GAK62860.1 - 0.048 14.1 3.0 0.048 14.1 3.0 3.4 3 0 0 3 3 2 0 RNA-binding, Nab2-type zinc finger CEBP_ZZ PF16366.5 GAK62860.1 - 0.1 12.9 6.0 0.32 11.3 6.0 1.9 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-rbx1 PF12678.7 GAK62860.1 - 0.11 12.8 11.3 0.093 13.0 8.6 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 GAK62860.1 - 0.27 10.9 6.0 0.83 9.3 6.0 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_9 PF14369.6 GAK62860.1 - 2.8 8.3 7.7 0.34 11.2 2.5 2.3 2 0 0 2 2 2 0 zinc-ribbon RPE65 PF03055.15 GAK62861.1 - 8e-118 394.6 0.0 9.4e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SNF2_N PF00176.23 GAK62862.1 - 1.2e-43 149.2 0.0 1.8e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK62862.1 - 3.7e-22 78.8 0.0 4.8e-20 72.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 GAK62862.1 - 2.4e-12 46.8 0.0 7.6e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.15 GAK62862.1 - 3e-07 30.6 0.0 5.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAK62862.1 - 0.00018 20.8 0.0 0.00035 19.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SOG2 PF10428.9 GAK62863.1 - 2 7.5 14.8 2.2 7.4 14.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PPC PF04151.15 GAK62863.1 - 6.5 7.9 11.7 26 6.0 11.6 2.2 1 1 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Elf1 PF05129.13 GAK62865.1 - 8.6e-30 102.6 0.7 9.6e-30 102.5 0.7 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 GAK62865.1 - 0.079 13.0 3.7 4.3 7.5 0.1 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Ank_4 PF13637.6 GAK62866.1 - 3.3e-13 49.9 0.2 4.9e-06 27.0 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK62866.1 - 9.6e-11 42.1 0.1 3.3e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAK62866.1 - 2.2e-10 40.6 0.0 2.6e-08 34.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAK62866.1 - 1.4e-06 28.1 0.0 4e-05 23.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAK62866.1 - 8.2e-06 26.0 0.2 4.2e-05 23.8 0.2 2.2 3 0 0 3 3 3 1 Ankyrin repeat HSP70 PF00012.20 GAK62867.1 - 3e-257 854.7 11.9 3e-257 854.7 11.9 1.7 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GAK62867.1 - 2.3e-18 66.1 0.3 1.3e-17 63.7 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein zf-U1 PF06220.12 GAK62867.1 - 1.7e-07 30.9 0.7 3.5e-07 29.9 0.7 1.6 1 0 0 1 1 1 1 U1 zinc finger Hydantoinase_A PF01968.18 GAK62867.1 - 0.02 14.1 5.4 0.12 11.6 0.1 3.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF4624 PF15417.6 GAK62867.1 - 0.034 13.9 0.0 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4624) DUF2680 PF10925.8 GAK62867.1 - 0.23 11.5 7.3 0.13 12.3 0.2 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2680) TRAF_BIRC3_bd PF16673.5 GAK62867.1 - 0.27 11.0 1.7 2.7 7.9 0.4 2.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF357 PF04010.13 GAK62867.1 - 0.36 10.9 1.6 3.6 7.7 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF357) IU_nuc_hydro PF01156.19 GAK62868.1 - 3e-84 283.2 0.0 4.4e-84 282.6 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase S1-P1_nuclease PF02265.16 GAK62869.1 - 1.9e-47 162.3 0.0 3.5e-45 154.8 0.0 2.5 1 1 0 1 1 1 1 S1/P1 Nuclease LRR_6 PF13516.6 GAK62870.1 - 1.2e-06 28.1 0.6 6.2 7.2 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich repeat F-box PF00646.33 GAK62870.1 - 0.018 14.9 0.0 0.066 13.1 0.0 2.0 1 0 0 1 1 1 0 F-box domain Fibrillarin PF01269.17 GAK62870.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin LRR_1 PF00560.33 GAK62870.1 - 0.23 12.1 1.5 38 5.4 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 GAK62870.1 - 4.5 7.8 9.5 8.7 6.9 0.6 4.1 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) ATP-synt_G PF04718.15 GAK62871.1 - 1.5e-15 57.8 0.2 2.9e-15 56.9 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF5399 PF17377.2 GAK62871.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5399) DUF1674 PF07896.12 GAK62871.1 - 0.16 12.4 0.2 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) EF-hand_6 PF13405.6 GAK62872.1 - 1e-13 50.0 0.7 1.3e-05 24.7 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 GAK62872.1 - 1.9e-13 50.7 0.3 3e-07 30.8 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAK62872.1 - 2.8e-12 45.3 1.8 1.1e-05 24.7 0.1 3.4 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 GAK62872.1 - 1.1e-05 25.7 0.0 0.001 19.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 GAK62872.1 - 1.1e-05 25.2 0.3 0.0038 17.0 0.0 3.2 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 GAK62872.1 - 0.00012 21.4 0.4 0.0036 16.7 0.2 2.7 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.10 GAK62872.1 - 0.006 16.7 0.0 0.95 9.6 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand FGAR-AT_linker PF18072.1 GAK62872.1 - 0.16 12.5 0.0 16 6.2 0.0 2.4 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_11 PF08976.11 GAK62872.1 - 0.2 12.5 0.0 0.83 10.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain DUF3602 PF12223.8 GAK62873.1 - 5.9e-16 58.8 23.4 1.7e-13 51.0 5.8 4.1 2 1 2 4 4 4 3 Protein of unknown function (DUF3602) RNase_PH_C PF03725.15 GAK62874.1 - 7e-10 38.8 0.0 2.9e-09 36.8 0.0 2.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 GAK62874.1 - 1.3e-09 38.6 0.0 2.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Methyltransf_25 PF13649.6 GAK62875.1 - 1.5e-17 64.1 0.0 1.6e-16 60.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK62875.1 - 2.8e-15 56.5 0.0 5.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK62875.1 - 7.5e-15 55.4 0.0 4.1e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK62875.1 - 1.7e-09 37.7 0.0 3.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK62875.1 - 4.4e-09 36.0 0.0 7.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAK62875.1 - 8.2e-08 32.9 0.0 2.5e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK62875.1 - 0.00057 19.5 0.0 0.0015 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 GAK62875.1 - 0.034 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 GAK62875.1 - 0.17 11.4 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Skp1_POZ PF03931.15 GAK62876.1 - 1.7e-09 37.7 0.0 4.7e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.31 GAK62877.1 - 1.1e-08 35.1 0.2 0.00059 20.0 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAK62877.1 - 0.00045 20.4 0.0 0.039 14.2 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAK62877.1 - 0.024 14.5 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Myb DNA-binding like UQ_con PF00179.26 GAK62878.1 - 2.5e-53 179.5 0.0 2.8e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAK62878.1 - 0.0029 17.9 0.0 0.0039 17.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GAK62878.1 - 0.0062 16.2 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAK62878.1 - 0.044 13.6 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain Cys_rich_CWC PF14375.6 GAK62879.1 - 0.076 13.4 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC EphA2_TM PF14575.6 GAK62880.1 - 0.085 13.7 0.0 0.2 12.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 GAK62880.1 - 0.14 12.4 1.7 0.52 10.6 0.0 2.8 2 1 1 3 3 3 0 Glycophorin A Glyco_tran_28_C PF04101.16 GAK62881.1 - 1.5e-19 70.6 0.0 1.7e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain MOSC_N PF03476.16 GAK62882.1 - 1.1e-20 73.8 0.0 1.9e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 GAK62882.1 - 3.8e-20 72.2 0.0 7.6e-20 71.3 0.0 1.5 1 1 0 1 1 1 1 MOSC domain Csm1 PF12539.8 GAK62883.1 - 3.9e-06 27.4 0.0 1.3e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 vWF_A PF12450.8 GAK62883.1 - 0.16 11.9 2.2 0.48 10.4 2.2 1.9 1 0 0 1 1 1 0 von Willebrand factor Ras PF00071.22 GAK62884.1 - 1.6e-58 196.9 0.1 1.9e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK62884.1 - 9.6e-21 74.2 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK62884.1 - 5.7e-09 35.7 0.0 6.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAK62884.1 - 8.7e-06 25.4 0.1 2.2e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAK62884.1 - 0.00013 21.9 0.3 0.25 11.3 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAK62884.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAK62884.1 - 0.0099 15.7 1.2 0.12 12.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 GAK62884.1 - 0.01 15.4 0.0 0.029 13.9 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Ser_hydrolase PF06821.13 GAK62884.1 - 0.081 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase G-alpha PF00503.20 GAK62884.1 - 0.12 11.6 0.2 3.3 6.8 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit GDA1_CD39 PF01150.17 GAK62885.1 - 3.3e-103 345.6 0.0 4.6e-103 345.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DFRP_C PF16543.5 GAK62886.1 - 4.4e-31 107.2 2.9 4.4e-31 107.2 2.9 3.6 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 GAK62886.1 - 0.0011 19.0 7.1 0.0011 19.0 7.1 3.5 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 GAK62886.1 - 0.0088 16.3 5.1 0.061 13.6 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger containing family PTPS PF01242.19 GAK62886.1 - 0.014 15.4 2.2 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase zf-CCCH PF00642.24 GAK62886.1 - 0.021 14.8 1.7 0.021 14.8 1.7 2.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAK62886.1 - 0.03 15.0 19.4 0.44 11.3 7.2 4.2 2 1 1 3 3 3 0 Torus domain zf-CCCH_4 PF18044.1 GAK62886.1 - 0.4 10.5 11.7 0.71 9.7 2.2 3.3 3 0 0 3 3 3 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAK62886.1 - 0.48 11.0 11.8 2.7 8.6 3.0 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Tyr-DNA_phospho PF06087.12 GAK62887.1 - 7.9e-37 127.1 0.0 1.4e-36 126.3 0.0 1.3 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PAPA-1 PF04795.12 GAK62887.1 - 0.041 14.7 4.4 0.094 13.5 4.4 1.6 1 0 0 1 1 1 0 PAPA-1-like conserved region SET PF00856.28 GAK62888.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.6 1 1 0 1 1 1 0 SET domain DUF4201 PF13870.6 GAK62889.1 - 0.0012 18.6 5.1 0.0012 18.6 5.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) DUF4763 PF15960.5 GAK62889.1 - 0.18 11.1 7.0 2.3 7.5 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 GAK62889.1 - 0.58 10.3 24.7 0.037 14.2 11.7 3.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAK62889.1 - 0.84 8.5 13.0 0.71 8.7 6.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Csm1_N PF18504.1 GAK62889.1 - 1.7 9.0 12.7 0.81 10.1 0.3 3.7 2 1 1 3 3 3 0 Csm1 N-terminal domain Fez1 PF06818.15 GAK62889.1 - 4.5 7.7 16.6 1.9 8.9 7.3 2.7 3 0 0 3 3 3 0 Fez1 SAM_decarbox PF01536.16 GAK62891.1 - 1.3e-128 428.9 0.0 2.1e-128 428.3 0.0 1.2 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SPT6_acidic PF14632.6 GAK62892.1 - 0.014 15.9 2.2 0.014 15.9 2.2 5.2 4 2 1 5 5 5 0 Acidic N-terminal SPT6 Pex24p PF06398.11 GAK62893.1 - 7.5e-05 21.9 7.7 0.00012 21.3 7.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin IF-2B PF01008.17 GAK62894.1 - 7.9e-56 189.3 0.4 2.5e-49 168.0 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family PPP4R2 PF09184.11 GAK62894.1 - 0.0037 16.9 4.8 0.0056 16.3 4.8 1.2 1 0 0 1 1 1 1 PPP4R2 CENP-B_dimeris PF09026.10 GAK62894.1 - 0.0047 17.3 9.4 0.01 16.2 9.4 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF2076 PF09849.9 GAK62894.1 - 0.0078 16.3 8.3 0.014 15.4 8.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) PBP1_TM PF14812.6 GAK62894.1 - 0.0086 16.4 4.3 0.015 15.7 4.3 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Serglycin PF04360.12 GAK62894.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Serglycin Nop14 PF04147.12 GAK62894.1 - 0.06 11.6 7.5 0.084 11.1 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GAK62894.1 - 0.068 12.3 18.2 0.1 11.7 18.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3245 PF11595.8 GAK62894.1 - 0.2 12.1 5.2 0.4 11.2 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) FAM176 PF14851.6 GAK62894.1 - 0.42 10.3 3.8 0.81 9.3 3.8 1.5 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 GAK62894.1 - 0.59 10.2 4.8 1.1 9.3 4.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 GAK62894.1 - 0.66 9.7 13.0 1.1 8.9 13.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAK62894.1 - 0.69 9.2 12.4 1.1 8.6 12.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 GAK62894.1 - 1.9 7.2 3.8 2.9 6.6 3.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RNA_pol_3_Rpc31 PF11705.8 GAK62894.1 - 2.2 8.5 13.0 3.7 7.7 13.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 GAK62894.1 - 4.3 5.8 7.6 6.7 5.1 7.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FYDLN_acid PF09538.10 GAK62894.1 - 5.9 7.6 12.7 12 6.7 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 GAK62894.1 - 6 4.8 19.9 2.6 6.0 16.6 1.8 2 0 0 2 2 2 0 DNA polymerase phi Nop53 PF07767.11 GAK62894.1 - 8.4 5.7 9.4 14 4.9 9.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DASH_Ask1 PF08655.10 GAK62895.1 - 2e-27 94.8 0.1 3.5e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 CBS PF00571.28 GAK62896.1 - 9.5e-08 32.4 1.4 0.00027 21.3 0.1 4.3 5 0 0 5 5 5 2 CBS domain Collagen_mid PF15984.5 GAK62896.1 - 0.0082 15.9 1.5 0.018 14.8 1.5 1.5 1 0 0 1 1 1 1 Bacterial collagen, middle region AIRC PF00731.20 GAK62897.1 - 1.2e-64 216.4 2.8 3.2e-64 215.0 2.8 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 GAK62897.1 - 1.1e-53 181.3 0.1 2.1e-53 180.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 GAK62897.1 - 3.5e-19 68.2 0.0 8.4e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 GAK62897.1 - 3.1e-05 23.6 0.0 0.00023 20.8 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 GAK62897.1 - 0.0029 16.9 0.1 0.0098 15.2 0.1 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAK62897.1 - 0.0036 17.2 0.0 0.013 15.4 0.0 2.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAK62897.1 - 0.051 12.9 0.2 0.16 11.4 0.2 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 GAK62897.1 - 0.12 12.9 0.7 22 5.6 0.0 3.0 2 1 1 3 3 3 0 CoA binding domain DSPc PF00782.20 GAK62898.1 - 3.9e-25 88.2 0.0 6e-18 65.0 0.0 3.4 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAK62898.1 - 0.0028 17.2 0.0 0.059 12.9 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF2924 PF11149.8 GAK62898.1 - 0.11 12.9 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) RRM_1 PF00076.22 GAK62899.1 - 4.5e-16 58.4 0.0 7.2e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GAK62899.1 - 5.2e-07 30.1 3.6 5.2e-07 30.1 3.6 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 GAK62899.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif RRM_7 PF16367.5 GAK62899.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif ThiF PF00899.21 GAK62900.1 - 5.2e-72 242.1 0.1 8.4e-72 241.4 0.1 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 GAK62900.1 - 2.2e-14 54.0 0.0 1.1e-07 32.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 GAK62900.1 - 8.3e-09 35.9 1.1 1.7e-08 34.9 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 GAK62900.1 - 0.0025 17.9 0.1 0.0063 16.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 GAK62900.1 - 0.013 16.0 0.2 0.55 10.8 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAK62900.1 - 0.018 15.5 0.1 0.066 13.7 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Ldh_1_N PF00056.23 GAK62900.1 - 0.047 13.8 0.5 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAK62900.1 - 0.091 13.0 0.4 0.65 10.3 0.4 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain VHS PF00790.19 GAK62901.1 - 3.3e-40 137.2 0.0 1.1e-39 135.5 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 GAK62901.1 - 2.3e-20 72.7 0.0 1.4e-19 70.1 0.0 2.4 3 1 0 3 3 3 1 GAT domain FHA PF00498.26 GAK62902.1 - 0.0019 18.5 0.1 0.006 16.9 0.1 1.9 1 1 0 1 1 1 1 FHA domain DTHCT PF08070.11 GAK62902.1 - 8.7 7.1 12.6 0.31 11.8 3.9 3.1 3 0 0 3 3 3 0 DTHCT (NUC029) region PAC3 PF10178.9 GAK62903.1 - 0.00012 22.1 1.2 0.0003 20.9 1.2 1.6 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 Citrate_bind PF16114.5 GAK62904.1 - 4.9e-88 293.3 0.5 1.6e-87 291.6 0.1 1.9 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 GAK62904.1 - 3.8e-19 69.0 0.0 1.2e-16 60.8 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 GAK62904.1 - 9.7e-15 54.7 0.1 1.8e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 GAK62904.1 - 4.3e-13 49.8 0.0 1.4e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 GAK62904.1 - 1.6e-07 31.1 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 GAK62904.1 - 8.6e-06 25.6 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 GAK62904.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Ivy PF08816.11 GAK62904.1 - 0.21 11.8 0.3 30 4.9 0.1 2.4 1 1 1 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) NAD_binding_10 PF13460.6 GAK62905.1 - 7.2e-09 35.8 0.1 1.2e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAK62905.1 - 0.00013 21.5 0.0 0.00083 18.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAK62905.1 - 0.0035 17.8 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Asparaginase PF00710.20 GAK62906.1 - 2.2e-54 183.9 0.0 2.7e-50 170.6 0.0 2.3 2 0 0 2 2 2 2 Asparaginase, N-terminal Asparaginase_C PF17763.1 GAK62906.1 - 5.5e-33 113.6 0.0 1.5e-32 112.2 0.0 1.8 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 GAK62906.1 - 3.1e-08 34.1 0.1 9.4e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK62906.1 - 4.5e-05 23.9 0.1 0.0002 21.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAK62906.1 - 0.00011 22.5 1.3 0.33 11.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAK62906.1 - 0.00046 20.4 0.1 3.9 8.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAK62906.1 - 0.002 18.4 0.4 0.16 12.3 0.0 3.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Pex14_N PF04695.13 GAK62906.1 - 0.036 14.7 0.9 0.096 13.3 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1744 PF08490.12 GAK62907.1 - 2.9e-132 441.0 0.0 4.8e-132 440.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 GAK62907.1 - 6.7e-79 265.5 0.0 1.2e-78 264.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GAK62907.1 - 2.1e-13 49.8 1.2 2e-11 43.3 0.7 3.1 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 GAK62907.1 - 5.6e-10 39.3 0.2 2.8e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAK62907.1 - 3.7e-05 23.8 0.0 0.00015 21.8 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily T3SS_needle_E PF08988.10 GAK62907.1 - 0.073 13.2 0.1 0.45 10.7 0.1 2.4 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle YhdX PF17444.2 GAK62907.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized YhdX-like Glycogen_syn PF05693.13 GAK62908.1 - 0 1117.0 0.0 0 1116.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 GAK62908.1 - 1.9e-07 30.8 0.0 6.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAK62908.1 - 6.6e-07 29.3 0.3 2.9e-06 27.1 0.2 2.1 1 1 1 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 GAK62908.1 - 3.3e-06 27.6 0.0 0.0027 18.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAK62908.1 - 4.6e-05 23.9 0.1 9.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAK62908.1 - 0.00021 21.3 0.8 0.00038 20.5 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Dala_Dala_lig_C PF07478.13 GAK62908.1 - 0.08 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DBR1 PF05011.13 GAK62910.1 - 1.2e-38 132.7 0.0 1.9e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 GAK62910.1 - 8.6e-06 26.4 0.1 1.4e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAK62910.1 - 0.034 14.3 0.0 0.059 13.6 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RA PF00788.23 GAK62911.1 - 2e-13 50.7 0.0 1.1e-10 42.0 0.0 2.9 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 GAK62911.1 - 9e-08 31.6 0.0 1.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK62911.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TUG-UBL1 PF11470.8 GAK62911.1 - 0.12 12.6 0.0 8.3 6.7 0.0 2.5 2 0 0 2 2 2 0 TUG ubiquitin-like domain La PF05383.17 GAK62912.1 - 1.4e-17 63.4 0.0 2.4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 La domain Thioredoxin PF00085.20 GAK62913.1 - 1.1e-21 76.7 0.0 1.4e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAK62913.1 - 0.00012 22.5 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 GAK62913.1 - 0.2 11.8 0.0 0.54 10.4 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin 6PF2K PF01591.18 GAK62914.1 - 1.1e-60 204.7 0.0 1.6e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAK62914.1 - 1.5e-23 83.6 0.2 9e-22 77.7 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Efg1 PF10153.9 GAK62915.1 - 4.5e-30 104.3 4.8 4.5e-30 104.3 4.8 2.5 2 1 0 2 2 2 1 rRNA-processing protein Efg1 UPF0565 PF10561.9 GAK62915.1 - 0.13 11.4 0.3 0.33 10.1 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF3336 PF11815.8 GAK62916.1 - 4.8e-44 149.4 0.7 7.5e-44 148.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAK62916.1 - 1.6e-17 64.4 1.0 1.5e-16 61.2 0.0 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase Pro_isomerase PF00160.21 GAK62917.1 - 1.2e-44 152.4 0.1 1.7e-44 151.9 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD E1-E2_ATPase PF00122.20 GAK62918.1 - 2.1e-34 118.6 0.1 6.2e-34 117.1 0.1 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAK62918.1 - 5.1e-26 92.3 1.2 1.5e-25 90.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAK62918.1 - 8.2e-21 74.2 7.9 2.4e-07 31.1 0.1 5.0 4 1 0 4 4 4 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAK62918.1 - 0.0031 17.3 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 GAK62918.1 - 1.8 8.9 4.6 35 4.8 0.0 4.2 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain DPBB_1 PF03330.18 GAK62920.1 - 2.9e-05 24.2 0.2 0.00043 20.5 0.1 2.3 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 GAK62920.1 - 0.072 12.9 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Barwin family GPHR_N PF12537.8 GAK62920.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal AICARFT_IMPCHas PF01808.18 GAK62921.1 - 1.6e-89 300.3 0.2 2.5e-89 299.6 0.2 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 GAK62921.1 - 6e-23 80.8 0.0 2.6e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain CBM_25 PF03423.13 GAK62921.1 - 0.32 11.3 1.6 2.4 8.4 0.1 2.8 3 0 0 3 3 3 0 Carbohydrate binding domain (family 25) FAD-oxidase_C PF02913.19 GAK62922.1 - 6.7e-55 186.4 0.0 9.6e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAK62922.1 - 1.2e-32 112.5 0.0 2.6e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Polysacc_synt_4 PF04669.13 GAK62923.1 - 1.2e-17 64.1 2.2 4.6e-16 58.9 2.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis Acyl-CoA_dh_1 PF00441.24 GAK62924.1 - 1.1e-50 171.7 2.4 2.5e-50 170.6 2.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAK62924.1 - 6.4e-28 96.8 0.3 1.6e-27 95.6 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAK62924.1 - 2.6e-25 89.3 0.2 6.9e-25 87.9 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAK62924.1 - 7.3e-21 74.9 2.6 7.3e-21 74.9 2.6 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAK62924.1 - 2.1e-06 27.6 0.3 8.5e-06 25.6 0.3 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal OrfB_Zn_ribbon PF07282.11 GAK62926.1 - 1.2e-08 34.7 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain GATA PF00320.27 GAK62928.1 - 1e-30 105.0 18.2 2e-15 56.1 3.3 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAK62928.1 - 8.1e-06 25.3 6.4 0.021 14.3 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 GAK62928.1 - 0.00041 20.4 2.2 0.42 10.8 0.3 2.7 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 GAK62928.1 - 0.011 15.9 5.6 1.2 9.3 0.5 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArfGap PF01412.18 GAK62928.1 - 0.034 14.2 4.2 1.6 8.8 0.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zinc_ribbon_4 PF13717.6 GAK62928.1 - 0.15 12.0 2.0 7 6.7 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 GAK62928.1 - 0.21 11.3 6.3 0.4 10.4 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-piccolo PF05715.13 GAK62928.1 - 2.4 8.4 4.3 14 5.9 0.0 3.3 4 0 0 4 4 4 0 Piccolo Zn-finger OrfB_Zn_ribbon PF07282.11 GAK62928.1 - 2.7 8.0 6.5 3.1 7.8 0.7 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Vps36-NZF-N PF16988.5 GAK62928.1 - 3.4 7.1 4.9 20 4.7 0.1 3.3 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CPSase_L_D2 PF02786.17 GAK62929.1 - 4.7e-82 274.6 0.1 7.4e-82 273.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAK62929.1 - 5.2e-69 232.0 0.0 8.5e-69 231.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAK62929.1 - 6.8e-40 136.0 0.0 1.5e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAK62929.1 - 1.1e-29 102.7 0.0 2.5e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAK62929.1 - 8e-29 101.0 0.0 1.6e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAK62929.1 - 5.8e-15 54.9 1.0 1.2e-14 53.9 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAK62929.1 - 4.2e-13 48.9 0.0 2.1e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAK62929.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAK62929.1 - 1.4e-07 31.2 0.0 4e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAK62929.1 - 3.5e-05 23.9 0.0 6.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 GAK62929.1 - 6.5e-05 22.2 0.1 0.018 14.3 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 GAK62929.1 - 7.3e-05 23.4 0.1 0.48 11.2 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.11 GAK62929.1 - 0.00021 21.0 0.0 0.0007 19.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 GAK62929.1 - 0.00039 20.2 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 GAK62929.1 - 0.0016 18.0 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain NQRA PF05896.11 GAK62929.1 - 0.036 13.5 0.6 0.068 12.6 0.2 1.6 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_ST PF14397.6 GAK62929.1 - 0.053 12.8 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 GAK62929.1 - 0.082 12.9 0.6 2.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Ribosomal_S13 PF00416.22 GAK62931.1 - 5.5e-53 178.7 2.3 6.4e-53 178.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 GAK62931.1 - 0.0033 17.8 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) FbpA PF05833.11 GAK62931.1 - 0.0074 15.1 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Mito_carr PF00153.27 GAK62932.1 - 6.2e-67 221.6 5.5 7.3e-22 77.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF1282 PF06930.12 GAK62932.1 - 0.00051 19.9 0.2 0.64 9.8 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1282) PBP-Tp47_a PF14889.6 GAK62932.1 - 0.081 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Clat_adaptor_s PF01217.20 GAK62933.1 - 6.8e-49 165.4 0.1 1.2e-35 122.6 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain SHR3_chaperone PF08229.11 GAK62934.1 - 1.8e-46 157.5 0.1 2.2e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Neurensin PF14927.6 GAK62934.1 - 0.029 14.1 0.5 0.34 10.6 0.7 2.3 1 1 0 1 1 1 0 Neurensin DUF1772 PF08592.11 GAK62934.1 - 0.1 12.9 0.5 0.15 12.3 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) AAA PF00004.29 GAK62935.1 - 8.2e-97 320.7 0.0 5.8e-47 159.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK62935.1 - 5.1e-26 90.2 9.6 1e-12 47.6 0.4 3.3 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 GAK62935.1 - 8.6e-19 67.5 0.2 3.1e-18 65.7 0.1 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GAK62935.1 - 1.3e-14 54.2 0.1 5.6e-06 26.2 0.0 3.4 2 2 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAK62935.1 - 1.9e-12 47.7 0.0 3.2e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAK62935.1 - 8.6e-12 45.4 0.0 8.2e-06 26.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.17 GAK62935.1 - 3.7e-11 42.7 0.0 7.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 GAK62935.1 - 4.1e-11 43.5 0.7 0.0012 19.3 0.0 4.5 3 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAK62935.1 - 6e-11 42.5 0.1 1.7e-05 24.8 0.1 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAK62935.1 - 3.2e-09 36.4 0.1 0.0015 17.8 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 GAK62935.1 - 2.2e-08 34.5 0.1 0.044 14.1 0.0 3.7 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAK62935.1 - 2e-07 30.6 0.3 0.014 14.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAK62935.1 - 6.1e-07 29.8 0.0 0.019 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 GAK62935.1 - 8.7e-07 28.5 0.1 0.51 9.6 0.0 3.5 3 0 0 3 3 3 2 KaiC IstB_IS21 PF01695.17 GAK62935.1 - 9.6e-07 28.7 0.0 0.024 14.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GAK62935.1 - 1.2e-06 29.1 0.0 0.024 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 GAK62935.1 - 2.9e-06 27.2 0.0 8.7e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 GAK62935.1 - 3e-06 26.9 0.0 0.025 14.1 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 GAK62935.1 - 3.4e-06 26.4 0.1 0.012 14.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GAK62935.1 - 3.5e-06 26.7 0.4 0.6 9.7 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 GAK62935.1 - 3.7e-06 27.0 0.0 0.018 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 GAK62935.1 - 1.4e-05 25.0 0.0 0.055 13.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Sigma54_activat PF00158.26 GAK62935.1 - 1.5e-05 24.7 0.0 0.35 10.6 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 GAK62935.1 - 1.7e-05 24.7 0.0 0.2 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 GAK62935.1 - 1.7e-05 25.1 0.0 0.13 12.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 GAK62935.1 - 2.8e-05 23.4 0.0 0.015 14.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAK62935.1 - 4.5e-05 24.0 0.0 0.24 11.9 0.0 3.5 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.16 GAK62935.1 - 0.00012 21.6 0.2 0.47 9.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein TsaE PF02367.17 GAK62935.1 - 0.00013 22.0 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 GAK62935.1 - 0.0002 21.4 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 GAK62935.1 - 0.00022 21.1 0.0 0.96 9.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GAK62935.1 - 0.00028 20.8 0.5 1 9.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 GAK62935.1 - 0.00039 19.8 0.0 0.49 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 GAK62935.1 - 0.00055 20.4 1.7 0.63 10.5 0.0 3.0 4 0 0 4 4 2 2 AAA domain ATPase_2 PF01637.18 GAK62935.1 - 0.00084 19.3 0.1 2.7 7.8 0.0 3.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 GAK62935.1 - 0.0018 18.2 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 GAK62935.1 - 0.0019 18.0 0.6 2.5 7.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 GAK62935.1 - 0.0023 18.1 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAK62935.1 - 0.0046 16.2 0.0 2.6 7.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 GAK62935.1 - 0.0049 16.1 0.0 0.82 8.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 GAK62935.1 - 0.006 16.3 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GAK62935.1 - 0.0095 16.3 2.8 3.5 7.9 0.0 3.5 3 1 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 GAK62935.1 - 0.023 14.6 0.4 4.2 7.3 0.0 3.5 3 0 0 3 3 3 0 NTPase UFD1 PF03152.14 GAK62935.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.12 GAK62935.1 - 0.043 13.5 0.0 1.7 8.2 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) IPT PF01745.16 GAK62935.1 - 0.047 13.1 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 GAK62935.1 - 0.052 13.3 0.0 8.4 6.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 GAK62935.1 - 0.062 12.3 0.0 1 8.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 GAK62935.1 - 0.078 12.2 0.0 0.55 9.4 0.0 2.2 2 1 0 2 2 2 0 KAP family P-loop domain Herpes_capsid PF06112.11 GAK62935.1 - 0.13 12.3 0.5 0.25 11.4 0.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PIF1 PF05970.14 GAK62935.1 - 0.19 10.9 0.0 7.5 5.6 0.0 2.8 3 0 0 3 3 3 0 PIF1-like helicase Hydin_ADK PF17213.3 GAK62935.1 - 1.1 9.5 3.3 82 3.4 0.0 3.6 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain UAA PF08449.11 GAK62936.1 - 1e-07 31.5 17.2 9.3e-07 28.3 17.2 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAK62936.1 - 0.00011 22.3 5.8 0.00011 22.3 5.8 2.4 2 0 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 GAK62936.1 - 2.5 7.4 18.5 0.14 11.4 1.3 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family MFS_1 PF07690.16 GAK62937.1 - 2.4e-33 115.5 39.4 6.1e-32 110.9 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK62937.1 - 1.3e-08 34.2 21.4 2.1e-07 30.2 21.4 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter UL42 PF17638.2 GAK62937.1 - 0.017 15.1 0.5 0.098 12.6 0.1 2.2 2 0 0 2 2 2 0 HCMV UL42 TRI12 PF06609.13 GAK62937.1 - 0.024 13.1 5.5 0.037 12.4 5.5 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Orn_Arg_deC_N PF02784.16 GAK62938.1 - 1.1e-73 247.7 0.0 1.5e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAK62938.1 - 2.2e-17 63.1 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain FA_desaturase PF00487.24 GAK62939.1 - 1.1e-23 84.4 26.2 1.8e-22 80.4 26.2 2.1 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 GAK62939.1 - 0.00012 22.2 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF1604 PF07713.13 GAK62940.1 - 8e-37 124.9 1.6 2.2e-36 123.5 1.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 GAK62940.1 - 2.1e-07 30.7 0.7 4.8e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 GAK62940.1 - 0.0032 17.5 0.7 0.021 14.9 0.2 2.5 2 0 0 2 2 2 1 G-patch domain WBS28 PF15164.6 GAK62942.1 - 0.053 12.8 0.9 0.09 12.1 0.9 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Aminotran_3 PF00202.21 GAK62943.1 - 2.1e-107 359.3 0.5 3.3e-107 358.6 0.5 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Forkhead PF00250.18 GAK62943.1 - 4.3e-31 107.0 0.0 8.1e-31 106.1 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Aminotran_1_2 PF00155.21 GAK62943.1 - 0.0025 17.1 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II NAD_binding_9 PF13454.6 GAK62944.1 - 0.00022 21.3 0.0 0.00071 19.6 0.0 2.0 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAK62944.1 - 0.00025 20.4 0.3 0.0079 15.5 0.2 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK62944.1 - 0.092 13.0 0.0 0.34 11.2 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAK62944.1 - 0.11 11.1 0.2 0.24 10.0 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein CDP-OH_P_transf PF01066.21 GAK62945.1 - 8e-17 61.8 0.2 8e-17 61.8 0.2 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PLA2_B PF01735.18 GAK62946.1 - 2.4e-141 471.5 2.1 3.2e-141 471.1 2.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 GAK62946.1 - 0.0011 19.2 1.0 0.0011 19.2 1.0 2.7 4 0 0 4 4 4 1 Patatin-like phospholipase Actin PF00022.19 GAK62947.1 - 1.6e-91 307.0 0.0 3e-90 302.8 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 GAK62947.1 - 0.023 15.1 0.0 0.2 12.1 0.0 2.6 2 1 0 2 2 2 0 Cell division protein FtsA Pkinase PF00069.25 GAK62948.1 - 3.7e-18 65.8 0.0 7.2e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 GAK62948.1 - 5.2e-15 55.6 1.9 3.9e-08 33.8 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 GAK62948.1 - 5.8e-11 41.7 4.2 0.11 12.9 0.0 6.9 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.17 GAK62948.1 - 1.3e-09 37.8 0.0 2.4e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.6 GAK62948.1 - 1e-05 25.8 1.6 2.8 8.4 0.4 4.3 2 1 1 3 3 3 3 HEAT repeats Kinase-like PF14531.6 GAK62948.1 - 0.00038 19.9 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like CNH PF00780.22 GAK62949.1 - 8.2e-66 222.4 0.0 1.2e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAK62949.1 - 2.4e-29 102.9 0.0 3.8e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 GAK62949.1 - 2.9e-06 27.4 0.0 0.00082 19.5 0.0 3.0 2 1 0 2 2 2 2 Pleckstrin homology domain DEP PF00610.21 GAK62949.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Acetyltransf_1 PF00583.25 GAK62950.1 - 6.9e-14 52.1 0.0 5.4e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK62950.1 - 1.7e-09 37.9 0.0 3.5e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAK62950.1 - 5e-07 29.7 0.1 0.027 14.4 0.1 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK62950.1 - 2.1e-05 24.4 0.1 0.004 17.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_13 PF13880.6 GAK62950.1 - 0.031 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 GAK62950.1 - 0.032 14.3 0.1 0.48 10.5 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain SPT2 PF08243.11 GAK62951.1 - 1.4e-19 70.7 25.3 1.4e-19 70.7 25.3 6.6 4 3 2 6 6 6 1 SPT2 chromatin protein PRMT5_TIM PF17285.2 GAK62952.1 - 7.7e-65 218.6 0.0 1.1e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GAK62952.1 - 1.3e-59 201.0 0.0 2.2e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GAK62952.1 - 9.3e-53 178.7 0.0 1.3e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 GAK62952.1 - 0.0033 18.1 0.0 0.0074 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK62952.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAK62952.1 - 0.17 12.6 0.0 0.46 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0047 PF01894.17 GAK62953.1 - 3.4e-35 120.7 0.0 4.7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RhoGAP PF00620.27 GAK62954.1 - 9.9e-46 155.3 0.1 1.4e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 GAK62954.1 - 0.038 14.5 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 PH domain PX PF00787.24 GAK62955.1 - 1.1e-07 31.8 0.0 3.4e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 PX domain PH PF00169.29 GAK62955.1 - 5.6e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAK62955.1 - 0.19 12.2 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIA PF03153.13 GAK62955.1 - 0.4 10.6 5.9 0.53 10.2 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CS PF04969.16 GAK62956.1 - 5.1e-07 30.6 0.0 1.1e-06 29.6 0.0 1.5 1 0 0 1 1 1 1 CS domain CRC_subunit PF08624.10 GAK62958.1 - 7.1e-44 149.5 0.0 2.7e-43 147.7 0.0 1.9 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Zn_clus PF00172.18 GAK62960.1 - 2.6e-09 37.1 7.7 5.1e-09 36.1 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 GAK62963.1 - 4.5e-21 75.2 0.0 8.1e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK62963.1 - 1.5e-08 34.5 0.0 3.7e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAK62963.1 - 4.2e-07 31.1 0.0 1.5e-06 29.3 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 GAK62963.1 - 0.099 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 GAK62963.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XRN_M PF17846.1 GAK62964.1 - 9.6e-103 344.5 1.7 1.1e-73 248.7 1.1 2.2 2 0 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 GAK62964.1 - 2.7e-97 325.0 0.0 4.4e-97 324.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 GAK62964.1 - 1.4e-70 237.0 0.0 4.5e-70 235.3 0.0 1.9 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 GAK62964.1 - 1.6e-24 85.9 0.0 4e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 GAK62964.1 - 5.5e-22 77.7 1.3 1.6e-21 76.2 0.4 2.1 2 0 0 2 2 2 1 Xrn1 SH3-like domain Lon_C PF05362.13 GAK62965.1 - 1.9e-66 223.5 0.1 3.8e-66 222.5 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GAK62965.1 - 5.2e-33 114.7 0.1 1.3e-32 113.4 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAK62965.1 - 4.3e-21 75.7 0.0 1.3e-20 74.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 GAK62965.1 - 1.7e-06 27.9 0.0 4.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 GAK62965.1 - 3.1e-06 27.2 0.0 7.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAK62965.1 - 2e-05 24.8 0.0 5.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 GAK62965.1 - 4.1e-05 22.7 0.0 6.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 GAK62965.1 - 0.00091 19.7 0.5 0.0053 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAK62965.1 - 0.002 18.4 0.1 0.063 13.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAK62965.1 - 0.0037 17.0 0.0 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAK62965.1 - 0.0075 16.8 0.0 0.0075 16.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 GAK62965.1 - 0.017 15.2 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAK62965.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAK62965.1 - 0.047 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 GAK62965.1 - 0.049 13.4 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 GAK62965.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 GAK62965.1 - 0.075 12.2 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.23 GAK62965.1 - 0.084 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 GAK62965.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAK62965.1 - 0.12 12.9 0.9 0.36 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 GAK62965.1 - 0.16 11.8 0.5 1.5 8.7 0.1 2.5 2 1 1 3 3 2 0 NTPase AAA_7 PF12775.7 GAK62965.1 - 0.27 10.7 0.4 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region PTPRCAP PF15713.5 GAK62965.1 - 5.6 7.2 10.9 0.32 11.3 4.9 2.0 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated Ribosomal_S16 PF00886.19 GAK62967.1 - 3.5e-27 94.2 0.2 9.1e-27 92.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S16 CMAS PF02353.20 GAK62968.1 - 4.8e-61 206.4 0.3 6.3e-61 206.1 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Bax1-I PF01027.20 GAK62968.1 - 1.4e-42 145.9 26.4 1.4e-42 145.9 26.4 2.2 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Methyltransf_11 PF08241.12 GAK62968.1 - 1.2e-12 48.3 0.0 3.6e-10 40.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK62968.1 - 8.4e-12 45.6 0.0 1.7e-10 41.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK62968.1 - 1.6e-09 37.8 0.0 3.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK62968.1 - 5.1e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK62968.1 - 4.2e-05 24.2 0.1 0.0002 22.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain DOT1 PF08123.13 GAK62968.1 - 0.00017 21.2 0.0 0.00081 19.0 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.14 GAK62968.1 - 0.0034 17.0 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain BaxI_1 PF12811.7 GAK62968.1 - 0.027 14.0 19.5 0.059 12.9 19.5 1.5 1 1 0 1 1 1 0 Bax inhibitor 1 like FtsJ PF01728.19 GAK62968.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 GAK62968.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2-Hacid_dh_C PF02826.19 GAK62969.1 - 8.7e-59 197.9 0.0 1.3e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAK62969.1 - 1.2e-20 73.6 0.1 1.4e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAK62969.1 - 3.4e-07 30.6 0.1 6.6e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAK62969.1 - 5.6e-05 23.6 0.0 0.00017 22.1 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 GAK62969.1 - 0.00083 19.0 0.3 0.0032 17.1 0.1 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain adh_short PF00106.25 GAK62969.1 - 0.028 13.9 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Gln-synt_C-ter PF18318.1 GAK62969.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain PGA2 PF07543.12 GAK62970.1 - 0.013 15.5 5.2 0.026 14.5 5.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SRAP PF02586.14 GAK62971.1 - 1e-64 218.1 0.0 1.9e-64 217.2 0.0 1.5 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_MLP1_2 PF07926.12 GAK62972.1 - 1.9e-22 79.7 20.3 1.9e-22 79.7 20.3 20.0 8 5 10 20 20 20 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 GAK62972.1 - 1.6e-05 24.0 19.5 1.6e-05 24.0 19.5 16.5 6 4 12 18 18 18 9 Spc7 kinetochore protein CC2-LZ PF16516.5 GAK62972.1 - 0.0032 17.8 5.2 0.0032 17.8 5.2 19.7 9 7 9 22 22 22 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fib_alpha PF08702.10 GAK62972.1 - 0.0039 17.4 6.0 0.0039 17.4 6.0 14.8 9 4 9 18 18 18 2 Fibrinogen alpha/beta chain family HALZ PF02183.18 GAK62972.1 - 0.043 14.0 0.2 0.043 14.0 0.2 12.5 17 1 1 18 18 18 0 Homeobox associated leucine zipper PLAC9 PF15205.6 GAK62972.1 - 0.072 13.5 1.4 2.7 8.4 0.1 3.8 2 0 0 2 2 2 0 Placenta-specific protein 9 DUF5600 PF18150.1 GAK62972.1 - 0.2 12.2 4.2 10 6.7 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) Cas_VVA1548 PF09652.10 GAK62972.1 - 0.85 9.9 3.8 9.4 6.6 0.2 4.0 3 0 0 3 3 3 0 Putative CRISPR-associated protein (Cas_VVA1548) SNARE PF05739.19 GAK62972.1 - 2.1 8.4 8.0 0.74 9.9 0.6 4.2 3 0 0 3 3 3 0 SNARE domain GRASP55_65 PF04495.14 GAK62973.1 - 9.1e-64 213.9 0.0 1.9e-55 186.9 0.0 2.1 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 GAK62973.1 - 7.2e-05 23.0 0.0 0.06 13.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 GAK62973.1 - 0.00017 21.3 1.0 0.4 10.6 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 GAK62973.1 - 0.07 13.5 0.0 15 6.1 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Sec34 PF04136.15 GAK62974.1 - 0.024 14.5 0.2 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 Sec34-like family F_actin_bind PF08919.10 GAK62974.1 - 0.041 14.0 0.5 0.14 12.3 0.5 1.9 1 0 0 1 1 1 0 F-actin binding BicD PF09730.9 GAK62974.1 - 0.36 9.2 9.5 0.015 13.8 2.6 2.1 2 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Muted PF14942.6 GAK62974.1 - 0.76 10.1 7.0 0.16 12.3 2.6 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein UPF0242 PF06785.11 GAK62974.1 - 1.8 8.6 8.2 0.062 13.4 0.6 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CLZ PF16526.5 GAK62974.1 - 2.2 8.7 7.4 5.8 7.3 7.4 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF812 PF05667.11 GAK62974.1 - 5.2 5.8 12.5 0.091 11.6 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) MCU PF04678.13 GAK62974.1 - 7.3 6.7 6.5 5.4 7.1 0.7 2.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter RdRP PF05183.12 GAK62975.1 - 1.2e-129 433.6 0.0 2e-103 347.1 0.0 2.1 2 0 0 2 2 2 2 RNA dependent RNA polymerase SCP2 PF02036.17 GAK62975.1 - 5e-09 36.6 0.0 1.5e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 SCP-2 sterol transfer family Pkinase PF00069.25 GAK62976.1 - 5e-34 117.9 0.0 1.7e-33 116.1 0.0 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK62976.1 - 2.5e-11 43.4 0.0 1.2e-10 41.2 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK62976.1 - 0.00024 20.6 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAK62976.1 - 0.0066 16.4 0.2 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family TFIIA_gamma_N PF02268.16 GAK62976.1 - 0.2 11.7 0.7 0.83 9.7 0.0 2.4 3 0 0 3 3 3 0 Transcription initiation factor IIA, gamma subunit, helical domain Aminotran_3 PF00202.21 GAK62977.1 - 4.8e-103 345.0 0.0 5.7e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAK62977.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II ThiF PF00899.21 GAK62978.1 - 1.1e-19 70.8 0.0 1.7e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family NDUFA12 PF05071.16 GAK62978.1 - 0.14 13.0 0.1 0.26 12.1 0.1 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-RRN7 PF11781.8 GAK62980.1 - 2.8e-07 30.1 0.1 5.6e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DHHC PF01529.20 GAK62981.1 - 7.2e-37 126.5 5.0 7.2e-37 126.5 5.0 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase AAA_23 PF13476.6 GAK62982.1 - 8.9e-34 117.7 0.7 8.9e-34 117.7 0.7 8.5 1 1 3 4 4 2 1 AAA domain AAA_21 PF13304.6 GAK62982.1 - 1.3e-11 44.9 4.1 1.2e-05 25.2 0.0 3.5 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAK62982.1 - 3.7e-07 29.8 0.0 3.7e-07 29.8 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAK62982.1 - 7.5e-07 29.2 62.6 0.00096 19.0 14.2 5.1 1 1 1 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 GAK62982.1 - 3.6e-06 27.1 0.0 1.3e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 GAK62982.1 - 1.6e-05 23.8 124.1 0.0064 15.2 0.0 7.3 2 1 3 5 5 5 3 AAA domain IFT57 PF10498.9 GAK62982.1 - 0.00094 18.2 11.4 0.00094 18.2 11.4 7.4 3 2 3 6 6 6 2 Intra-flagellar transport protein 57 ATG16 PF08614.11 GAK62982.1 - 0.0042 17.3 10.1 0.0042 17.3 10.1 10.1 3 2 7 10 10 10 4 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 GAK62982.1 - 0.0048 17.1 18.8 0.0048 17.1 18.8 9.2 3 3 6 9 9 6 3 Tropomyosin like AAA_29 PF13555.6 GAK62982.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 GAK62982.1 - 0.041 13.5 1.2 0.31 10.6 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Baculo_PEP_C PF04513.12 GAK62982.1 - 0.12 12.4 54.7 0.044 13.8 5.4 8.6 4 2 2 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 GAK62982.1 - 8.4 6.8 126.7 0.43 11.0 13.7 7.7 1 1 5 7 7 7 0 Fez1 Cullin PF00888.22 GAK62984.1 - 9e-181 602.6 3.0 1.2e-180 602.3 3.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAK62984.1 - 9.1e-27 92.9 4.4 2e-26 91.8 1.5 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain GntR PF00392.21 GAK62984.1 - 0.017 14.7 0.1 0.43 10.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Penicillinase_R PF03965.16 GAK62984.1 - 0.053 13.9 10.8 3.5 8.0 0.2 5.3 4 2 1 5 5 5 0 Penicillinase repressor Lipase_GDSL_2 PF13472.6 GAK62984.1 - 0.08 13.3 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Phage_rep_O PF04492.13 GAK62984.1 - 0.1 13.2 0.5 0.31 11.6 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage replication protein O Rrf2 PF02082.20 GAK62984.1 - 0.13 12.6 0.1 0.59 10.5 0.1 2.1 1 0 0 1 1 1 0 Transcriptional regulator AnfG_VnfG PF03139.15 GAK62984.1 - 0.21 11.7 3.0 0.21 11.7 0.3 2.4 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit KNOX2 PF03791.13 GAK62984.1 - 0.34 10.5 1.6 0.83 9.2 0.2 2.5 2 0 0 2 2 2 0 KNOX2 domain DUF4404 PF14357.6 GAK62984.1 - 0.67 10.6 4.5 2.1 9.0 0.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Ubie_methyltran PF01209.18 GAK62985.1 - 3.6e-73 245.8 0.2 3.5e-38 131.2 0.0 2.6 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAK62985.1 - 1.7e-13 51.1 0.0 1.5e-07 32.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAK62985.1 - 3.5e-12 46.9 0.0 5.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK62985.1 - 1.1e-10 42.1 0.0 9.2e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GAK62985.1 - 2.2e-09 37.3 0.0 1.2e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK62985.1 - 1.6e-07 31.3 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAK62985.1 - 0.0035 17.2 0.0 0.016 15.0 0.0 2.1 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_28 PF02636.17 GAK62985.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DIOX_N PF14226.6 GAK62986.1 - 0.0047 17.7 0.2 0.015 16.0 0.2 1.8 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Thiolase_N PF00108.23 GAK62987.1 - 6.5e-74 248.6 0.5 1.7e-73 247.2 0.1 1.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAK62987.1 - 2.2e-45 153.3 0.4 4e-45 152.4 0.4 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 GAK62987.1 - 0.0001 22.4 0.0 0.00029 20.9 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 GAK62987.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 2.4 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAK62987.1 - 0.018 14.9 2.2 0.22 11.4 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III BRCA-2_helical PF09169.10 GAK62987.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 BRCA2, helical DUF2093 PF09866.9 GAK62987.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) MazG-like PF12643.7 GAK62987.1 - 0.17 12.2 0.0 2.8 8.2 0.0 2.7 3 0 0 3 3 3 0 MazG-like family Sas10 PF09368.10 GAK62988.1 - 9.4e-28 96.5 4.3 9.4e-28 96.5 4.3 3.2 3 1 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 GAK62988.1 - 2.1e-07 31.4 0.1 9.2e-07 29.4 0.1 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fcf2 PF08698.11 GAK62989.1 - 2.6e-23 82.2 0.8 1.8e-20 73.2 0.2 3.3 3 0 0 3 3 3 2 Fcf2 pre-rRNA processing EPL1 PF10513.9 GAK62991.1 - 1.1e-24 87.6 0.0 1.1e-24 87.6 0.0 7.2 3 1 2 5 5 5 1 Enhancer of polycomb-like CK_II_beta PF01214.18 GAK62992.1 - 1.2e-75 253.4 0.0 1.4e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pho88 PF10032.9 GAK62993.1 - 4.5e-72 241.1 0.0 6.2e-72 240.7 0.0 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) Tom22 PF04281.13 GAK62994.1 - 3.7e-45 153.1 1.4 4.4e-45 152.9 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Pes-10 PF07149.11 GAK62994.1 - 0.23 10.5 6.2 0.34 9.9 6.2 1.2 1 0 0 1 1 1 0 Pes-10 FAM176 PF14851.6 GAK62994.1 - 0.68 9.6 4.4 0.73 9.5 3.4 1.5 2 0 0 2 2 2 0 FAM176 family RRN3 PF05327.11 GAK62994.1 - 1.6 7.2 3.4 1.9 6.9 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Arv1 PF04161.13 GAK62995.1 - 5.7e-18 65.8 0.0 2.5e-17 63.7 0.0 1.9 1 1 0 1 1 1 1 Arv1-like family VWA PF00092.28 GAK62996.1 - 5.8e-12 46.2 0.0 1.3e-11 45.1 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAK62996.1 - 1e-07 32.6 0.0 2.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 GAK62996.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Troponin PF00992.20 GAK62996.1 - 0.031 14.6 0.1 0.049 13.9 0.1 1.2 1 0 0 1 1 1 0 Troponin Integrin_beta PF00362.18 GAK62996.1 - 0.081 12.6 0.0 0.98 9.0 0.0 2.1 1 1 1 2 2 2 0 Integrin beta chain VWA domain HA2 PF04408.23 GAK62997.1 - 2.5e-26 92.1 0.0 5.2e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAK62997.1 - 3.6e-18 65.7 0.1 1.3e-17 63.9 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAK62997.1 - 1.1e-10 41.8 0.0 2.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK62997.1 - 4.5e-08 33.0 0.1 9.7e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK62997.1 - 3.4e-06 27.4 0.0 8.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK62997.1 - 4.2e-05 23.9 0.2 9.5e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GAK62997.1 - 0.0018 18.3 0.1 0.0065 16.5 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAK62997.1 - 0.0046 16.7 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAK62997.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 GAK62997.1 - 0.011 15.8 0.5 0.029 14.4 0.5 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.22 GAK62997.1 - 0.031 13.9 0.5 0.17 11.5 0.5 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Myosin_head PF00063.21 GAK62997.1 - 0.057 11.6 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Myosin head (motor domain) PhoH PF02562.16 GAK62997.1 - 0.06 12.8 0.0 0.39 10.1 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein AAA_14 PF13173.6 GAK62997.1 - 0.078 13.0 0.6 4.1 7.4 0.1 2.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 GAK62997.1 - 0.19 12.3 0.0 0.61 10.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter 3HCDH_N PF02737.18 GAK62998.1 - 1e-52 178.6 1.7 1.8e-52 177.8 1.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAK62998.1 - 9e-31 106.4 0.0 2.2e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 GAK62998.1 - 0.0011 18.9 0.7 0.0029 17.6 0.7 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 GAK62998.1 - 0.0018 17.9 0.7 0.0036 16.9 0.7 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAK62998.1 - 0.011 15.9 2.1 0.054 13.7 2.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 GAK62998.1 - 0.011 15.3 0.1 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1188) NAD_binding_2 PF03446.15 GAK62998.1 - 0.023 14.9 3.5 0.15 12.2 2.4 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 GAK62998.1 - 0.074 13.1 0.6 0.22 11.6 0.3 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAK62998.1 - 0.16 12.6 4.0 3.5 8.3 4.0 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 GAK62998.1 - 0.26 11.4 4.2 2.4 8.3 2.6 2.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus SR-25 PF10500.9 GAK62999.1 - 0.57 9.8 14.4 0.77 9.3 14.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hc1 PF07432.13 GAK62999.1 - 1.2 9.5 10.7 1.7 9.0 10.7 1.2 1 0 0 1 1 1 0 Histone H1-like protein Hc1 PGA2 PF07543.12 GAK62999.1 - 5.2 7.0 14.0 9.5 6.2 14.0 1.7 1 1 0 1 1 1 0 Protein trafficking PGA2 Nucleo_P87 PF07267.11 GAK62999.1 - 8.2 5.2 7.9 8.9 5.0 7.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Prefoldin PF02996.17 GAK63000.1 - 1.2e-27 96.2 3.7 1.6e-27 95.8 3.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.12 GAK63000.1 - 0.018 15.1 4.1 0.4 10.7 0.9 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Imm3 PF14425.6 GAK63000.1 - 0.023 14.7 0.3 0.037 14.1 0.3 1.3 1 0 0 1 1 1 0 Immunity protein Imm3 AIP3 PF03915.13 GAK63000.1 - 0.031 13.4 5.1 0.04 13.0 5.1 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1664 PF07889.12 GAK63000.1 - 0.034 14.2 6.6 0.83 9.7 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) XkdW PF09636.10 GAK63000.1 - 0.052 13.6 2.7 0.47 10.6 0.2 2.2 2 0 0 2 2 2 0 XkdW protein UPF0449 PF15136.6 GAK63000.1 - 0.15 12.5 5.0 5.2 7.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TORC_M PF12885.7 GAK63000.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain FlaC_arch PF05377.11 GAK63000.1 - 0.16 12.4 4.5 14 6.2 0.0 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 GAK63000.1 - 0.2 11.6 6.6 0.2 11.6 0.4 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PHM7_cyt PF14703.6 GAK63000.1 - 0.22 11.8 4.0 0.42 10.8 4.0 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter SlyX PF04102.12 GAK63000.1 - 0.22 12.2 11.2 0.34 11.5 7.0 2.3 2 0 0 2 2 2 0 SlyX DUF2508 PF10704.9 GAK63000.1 - 0.36 11.0 8.3 0.21 11.8 3.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) Fib_alpha PF08702.10 GAK63000.1 - 1.2 9.3 7.8 57 3.9 7.7 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 GAK63000.1 - 5.5 7.1 8.0 12 6.0 3.6 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-synt_DE_N PF02823.16 GAK63002.1 - 2.1e-15 56.3 0.1 2.9e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain TFA2_Winged_2 PF18121.1 GAK63003.1 - 9.2e-18 63.7 0.0 2.4e-17 62.4 0.0 1.7 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 GAK63003.1 - 1.2e-07 31.9 0.0 2.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain ABC_membrane_2 PF06472.15 GAK63005.1 - 1.3e-94 316.6 1.3 1.8e-94 316.2 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAK63005.1 - 2.3e-19 70.2 0.0 4.6e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAK63005.1 - 3.9e-05 23.6 0.0 0.0001 22.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAK63005.1 - 0.0013 19.3 0.2 0.025 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 GAK63005.1 - 0.019 14.4 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK63005.1 - 0.03 14.1 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 GAK63005.1 - 0.034 12.9 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 GAK63005.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 GAK63005.1 - 0.18 11.4 0.2 0.39 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain PPR_2 PF13041.6 GAK63006.1 - 6.3e-22 77.5 0.0 2.1e-06 27.8 0.0 6.3 5 1 1 6 6 6 4 PPR repeat family PPR PF01535.20 GAK63006.1 - 1.5e-14 53.1 2.0 0.0025 17.9 0.0 6.6 7 1 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 GAK63006.1 - 4.6e-10 39.4 0.0 0.0085 16.1 0.0 3.6 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAK63006.1 - 2.4e-07 30.4 1.2 0.0046 16.6 0.0 5.7 6 1 0 6 6 6 1 PPR repeat PPR_long PF17177.4 GAK63006.1 - 4.1e-06 26.3 0.2 0.059 12.7 0.0 3.1 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP Sec3_C PF09763.9 GAK63007.1 - 2.2e-194 647.8 0.0 3e-194 647.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 GAK63007.1 - 9.5e-24 83.4 0.2 1.8e-23 82.5 0.2 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 GAK63007.1 - 2.3e-05 23.3 0.7 2.3e-05 23.3 0.7 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family Ysc84 PF04366.12 GAK63008.1 - 6.1e-42 142.4 0.5 1.4e-41 141.2 0.1 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator Glyco_transf_8 PF01501.20 GAK63009.1 - 1.7e-15 57.3 0.0 5.4e-14 52.4 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 8 PI3_PI4_kinase PF00454.27 GAK63010.1 - 5.4e-53 180.4 0.0 1.3e-52 179.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAK63010.1 - 6e-25 88.2 0.2 1.3e-24 87.1 0.2 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 GAK63010.1 - 2.5e-23 81.9 0.0 1.3e-22 79.7 0.0 2.4 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 GAK63010.1 - 5.8e-10 38.8 0.1 1.5e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 GAK63010.1 - 0.0091 15.9 0.0 0.035 14.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) MOZART1 PF12554.8 GAK63011.1 - 2.9e-19 68.6 0.3 3.4e-19 68.3 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated GUN4_N PF16416.5 GAK63011.1 - 0.089 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal PBP1_TM PF14812.6 GAK63012.1 - 0.0079 16.5 6.9 0.28 11.6 0.4 3.0 3 0 0 3 3 3 2 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIE-A_C PF11521.8 GAK63012.1 - 1.5 9.2 5.7 0.65 10.3 1.2 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha CENP-B_dimeris PF09026.10 GAK63012.1 - 4.6 7.7 7.4 0.71 10.3 1.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PEP_mutase PF13714.6 GAK63013.1 - 1e-37 129.9 1.2 1.2e-37 129.7 1.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAK63013.1 - 1.1e-14 53.9 0.2 1.4e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family UreF PF01730.16 GAK63014.1 - 5.9e-19 69.0 0.4 1.5e-18 67.7 0.4 1.6 1 1 0 1 1 1 1 UreF FAM72 PF14976.6 GAK63019.1 - 1.6e-16 60.7 6.5 6.1e-16 58.9 6.5 1.8 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 GAK63019.1 - 0.16 12.2 3.9 8 6.7 1.3 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly OrfB_Zn_ribbon PF07282.11 GAK63019.1 - 7.2 6.6 8.3 0.7 9.9 0.1 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Oxysterol_BP PF01237.18 GAK63021.1 - 1.2e-118 396.2 0.0 2.4e-118 395.2 0.0 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 GAK63021.1 - 5.1e-17 61.9 0.0 1.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAK63021.1 - 1.9e-08 34.8 0.0 6.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 PH domain CoA_transf_3 PF02515.17 GAK63023.1 - 4.5e-32 111.6 0.8 1.2e-29 103.6 0.2 2.7 1 1 1 2 2 2 2 CoA-transferase family III IGPD PF00475.18 GAK63025.1 - 2.6e-60 202.9 0.5 7.7e-60 201.4 0.3 1.9 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase PLDc_2 PF13091.6 GAK63026.1 - 4.5e-16 59.0 0.0 2.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAK63026.1 - 6.3e-08 32.5 1.6 0.0073 16.5 0.2 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif MitMem_reg PF13012.6 GAK63027.1 - 5.9e-36 123.3 0.2 9.4e-36 122.6 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAK63027.1 - 1.7e-31 108.7 0.0 2.9e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Octopine_DH PF02317.17 GAK63027.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain AAA_11 PF13086.6 GAK63028.1 - 3.9e-71 239.9 0.3 6.7e-71 239.1 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 GAK63028.1 - 2.6e-51 174.1 0.0 4.2e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAK63028.1 - 2.6e-13 50.1 3.5 4.5e-12 46.1 0.8 2.7 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAK63028.1 - 6.3e-10 39.2 0.3 0.054 13.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GAK63028.1 - 2.7e-08 34.3 0.0 6.7e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAK63028.1 - 4.3e-05 22.9 1.0 0.013 14.8 0.4 3.1 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 GAK63028.1 - 9.7e-05 22.0 0.0 0.0022 17.6 0.1 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GAK63028.1 - 0.00019 21.8 2.1 0.0016 18.9 2.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 GAK63028.1 - 0.0002 21.1 0.0 0.00055 19.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 GAK63028.1 - 0.00027 21.2 0.1 0.0052 17.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAK63028.1 - 0.00032 20.3 0.2 0.001 18.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GAK63028.1 - 0.00068 19.1 0.0 0.76 9.2 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein DEAD PF00270.29 GAK63028.1 - 0.0021 17.8 0.0 0.016 15.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 GAK63028.1 - 0.0063 16.9 0.4 0.037 14.5 0.4 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAK63028.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 GAK63028.1 - 0.015 15.0 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Helicase_RecD PF05127.14 GAK63028.1 - 0.054 13.3 0.3 1.1 9.1 0.0 2.5 1 1 0 2 2 2 0 Helicase ResIII PF04851.15 GAK63028.1 - 0.079 13.0 0.0 1.5 8.8 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF5471 PF17565.2 GAK63028.1 - 0.11 12.7 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5471) UvrD_C PF13361.6 GAK63028.1 - 0.13 11.6 0.5 1.6 8.0 0.2 2.5 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain IKI3 PF04762.12 GAK63029.1 - 1.1e-276 920.6 0.0 1.4e-276 920.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 GAK63029.1 - 0.006 16.9 0.3 4 7.8 0.2 4.7 5 1 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Antimicrobial_1 PF08018.11 GAK63029.1 - 0.046 13.9 0.3 0.16 12.1 0.3 1.9 1 0 0 1 1 1 0 Frog antimicrobial peptide Se-cys_synth_N PF12390.8 GAK63029.1 - 0.05 13.8 1.0 0.14 12.4 0.1 2.4 2 0 0 2 2 2 0 Selenocysteine synthase N terminal TPR_12 PF13424.6 GAK63029.1 - 0.3 11.4 3.0 3 8.2 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 GAK63030.1 - 8e-66 222.1 0.0 1e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63030.1 - 3.6e-34 118.2 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK63030.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Ribosomal_L14 PF00238.19 GAK63031.1 - 1.2e-45 154.5 1.6 1.4e-45 154.3 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e MBOAT_2 PF13813.6 GAK63032.1 - 1.2e-06 28.7 3.6 1.9e-06 28.0 0.3 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PPR_2 PF13041.6 GAK63034.1 - 5.2e-41 138.6 0.1 4.9e-12 45.8 0.0 8.0 9 0 0 9 9 9 4 PPR repeat family PPR_3 PF13812.6 GAK63034.1 - 3.5e-32 110.3 0.0 7.7e-10 38.7 0.0 6.7 5 1 2 7 7 7 6 Pentatricopeptide repeat domain PPR PF01535.20 GAK63034.1 - 6.7e-31 104.4 1.5 0.00027 21.0 0.0 11.9 12 0 0 12 12 12 6 PPR repeat PPR_1 PF12854.7 GAK63034.1 - 1.5e-24 85.3 0.0 0.0018 18.0 0.0 7.7 8 0 0 8 8 8 5 PPR repeat PPR_long PF17177.4 GAK63034.1 - 2.9e-14 53.0 0.5 2.7e-11 43.3 0.1 4.5 4 1 1 5 5 5 1 Pentacotripeptide-repeat region of PRORP TPR_2 PF07719.17 GAK63034.1 - 0.00087 19.2 1.6 1.2 9.4 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAK63034.1 - 0.34 11.0 5.7 24 5.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat YEATS PF03366.16 GAK63035.1 - 1e-39 134.4 0.0 1.5e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family Tyrosinase PF00264.20 GAK63036.1 - 4.5e-17 63.1 3.4 7.7e-17 62.3 3.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase AvrRpt-cleavage PF05627.11 GAK63036.1 - 0.011 15.0 0.2 0.023 14.0 0.2 1.5 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr FAD_binding_7 PF03441.14 GAK63037.1 - 7.1e-51 172.6 1.2 1.2e-50 171.9 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAK63037.1 - 8.4e-23 81.2 0.0 2.2e-22 79.8 0.0 1.7 1 1 0 1 1 1 1 DNA photolyase 7TMR-DISMED2 PF07696.11 GAK63037.1 - 0.051 13.6 0.4 4.7 7.3 0.1 2.5 1 1 1 2 2 2 0 7TMR-DISM extracellular 2 RNA_pol_Rpb2_6 PF00562.28 GAK63038.1 - 6.2e-113 377.8 0.0 1.3e-112 376.7 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Porphobil_deam PF01379.20 GAK63038.1 - 3.5e-65 219.3 0.0 4.9e-61 205.8 0.0 2.3 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain RNA_pol_Rpb2_1 PF04563.15 GAK63038.1 - 9.9e-29 100.3 0.0 1.6e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 GAK63038.1 - 2.1e-26 91.9 0.0 7.3e-26 90.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 GAK63038.1 - 4.2e-23 81.1 0.0 1.6e-22 79.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 GAK63038.1 - 1e-18 67.6 0.0 1.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAK63038.1 - 1.7e-17 63.6 0.2 1.4e-14 54.2 0.1 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 Porphobil_deamC PF03900.15 GAK63038.1 - 4.3e-14 52.6 0.0 1.6e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain DUF848 PF05852.11 GAK63038.1 - 0.24 11.5 1.7 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ANAPC4_WD40 PF12894.7 GAK63039.1 - 0.00011 22.4 0.0 1.1 9.6 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAK63039.1 - 0.0053 17.6 3.3 6.1 7.9 0.0 5.5 7 0 0 7 7 7 1 WD domain, G-beta repeat BUD22 PF09073.10 GAK63039.1 - 5.5 6.2 6.8 8.4 5.6 6.8 1.2 1 0 0 1 1 1 0 BUD22 CitMHS PF03600.16 GAK63040.1 - 3.7e-10 39.5 5.9 3.7e-10 39.5 5.9 2.2 1 1 0 2 2 2 1 Citrate transporter ArsB PF02040.15 GAK63040.1 - 1.2e-05 24.9 13.7 4e-05 23.1 1.5 2.5 2 1 0 2 2 2 2 Arsenical pump membrane protein FtsJ PF01728.19 GAK63041.1 - 3.8e-43 147.7 0.0 5.2e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase N_methyl PF07963.12 GAK63042.1 - 1.6 8.4 0.0 1.6 8.4 0.0 3.1 4 0 0 4 4 4 0 Prokaryotic N-terminal methylation motif Pyr_redox_2 PF07992.14 GAK63043.1 - 2.4e-69 233.8 0.8 3.5e-69 233.3 0.5 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAK63043.1 - 8.1e-29 100.1 1.2 1.5e-28 99.2 1.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAK63043.1 - 1.8e-22 79.7 3.7 6.2e-19 68.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK63043.1 - 2.1e-13 50.2 0.0 4.8e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK63043.1 - 5.6e-06 25.3 2.9 0.11 11.2 0.0 3.1 2 1 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 GAK63043.1 - 1.5e-05 24.6 0.0 3.1e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAK63043.1 - 0.00057 19.1 0.1 0.0037 16.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAK63043.1 - 0.0071 16.6 0.7 0.021 15.0 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 GAK63043.1 - 0.03 14.7 0.1 8.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF576 PF04507.12 GAK63043.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Csa1 family FAD_binding_2 PF00890.24 GAK63043.1 - 0.24 10.4 6.1 0.11 11.6 2.8 2.1 3 0 0 3 3 3 0 FAD binding domain FH2 PF02181.23 GAK63044.1 - 2e-85 287.2 0.0 2e-85 287.2 0.0 2.9 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAK63044.1 - 1e-29 103.5 0.1 6.1e-21 74.8 0.0 3.6 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAK63044.1 - 1e-20 74.2 0.7 2.6e-20 72.9 0.7 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Erp_C PF06780.11 GAK63044.1 - 0.043 13.8 2.0 0.26 11.3 0.0 2.9 2 1 1 3 3 3 0 Erp protein C-terminus EPO_TPO PF00758.18 GAK63044.1 - 0.15 12.1 1.0 0.43 10.6 1.0 1.7 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Phlebovirus_NSM PF07246.11 GAK63044.1 - 3.6 6.9 7.6 8.7 5.6 7.6 1.6 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MRP-S25 PF13741.6 GAK63045.1 - 1.3e-63 214.6 0.6 2.3e-63 213.8 0.1 1.5 1 1 1 2 2 2 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 GAK63045.1 - 4.6e-07 30.1 0.5 0.032 14.5 0.2 2.5 2 0 0 2 2 2 2 Mitochondrial ribosomal protein S23 Polysacc_deac_1 PF01522.21 GAK63046.1 - 2.8e-20 72.5 0.3 9.1e-20 70.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Macoilin PF09726.9 GAK63046.1 - 3.3 6.2 7.4 3.9 5.9 7.4 1.1 1 0 0 1 1 1 0 Macoilin family Catalase PF00199.19 GAK63047.1 - 0.018 14.2 0.4 0.98 8.4 0.0 2.3 2 1 0 2 2 2 0 Catalase UPF0086 PF01868.16 GAK63048.1 - 3.4e-22 78.2 0.0 5.3e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L18p PF00861.22 GAK63048.1 - 0.18 12.2 8.1 0.072 13.5 3.9 2.3 2 1 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF5094 PF17015.5 GAK63048.1 - 0.87 9.7 2.9 1.6 8.8 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) BHD_2 PF10404.9 GAK63048.1 - 9.2 7.3 11.2 20 6.2 0.1 2.9 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 2 Velvet PF11754.8 GAK63049.1 - 3e-69 233.7 0.0 1.2e-68 231.8 0.0 1.8 2 0 0 2 2 2 1 Velvet factor COX6A PF02046.15 GAK63050.1 - 7.6e-36 123.0 1.7 9.1e-36 122.7 1.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Arm PF00514.23 GAK63051.1 - 3.2e-73 239.8 26.0 9.3e-12 44.6 0.1 11.5 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAK63051.1 - 1.1e-16 60.9 18.3 0.00026 21.4 0.4 8.6 6 3 3 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 GAK63051.1 - 7e-15 55.2 11.9 0.0077 16.6 0.0 7.2 4 2 2 7 7 6 4 HEAT repeats Adaptin_N PF01602.20 GAK63051.1 - 5.3e-11 41.8 6.3 1.2e-07 30.7 0.1 3.0 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 GAK63051.1 - 2.6e-10 40.2 4.3 2.6e-06 27.1 0.9 2.7 1 1 1 3 3 3 2 Armadillo-like HEAT PF02985.22 GAK63051.1 - 6.3e-10 38.4 24.6 0.83 10.1 0.0 10.2 12 0 0 12 12 10 4 HEAT repeat KAP PF05804.12 GAK63051.1 - 7e-10 37.7 0.1 1.4e-09 36.7 0.0 1.3 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 GAK63051.1 - 1.7e-08 34.1 4.3 0.0023 17.3 0.6 4.3 1 1 3 4 4 4 4 V-ATPase subunit H DUF3361 PF11841.8 GAK63051.1 - 2.4e-06 27.6 3.6 0.1 12.5 0.1 4.3 3 1 2 5 5 5 3 Domain of unknown function (DUF3361) Cnd1 PF12717.7 GAK63051.1 - 4.2e-05 23.6 5.0 0.15 12.1 0.1 4.2 2 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 GAK63051.1 - 0.00019 20.7 0.5 1 8.4 0.1 4.1 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) V-ATPase_H_C PF11698.8 GAK63051.1 - 0.00098 19.2 1.3 33 4.6 0.0 5.1 3 1 3 6 6 6 0 V-ATPase subunit H Proteasom_PSMB PF10508.9 GAK63051.1 - 0.019 13.5 1.5 6.2 5.2 0.0 3.5 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit YqfD PF06898.11 GAK63051.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Atx10homo_assoc PF09759.9 GAK63051.1 - 0.14 12.2 3.3 1.1 9.4 0.1 3.7 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 GAK63051.1 - 0.35 11.7 12.8 1.1e+02 4.0 0.0 7.4 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat Sigma70_r3 PF04539.16 GAK63052.1 - 0.0039 17.2 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 Sigma-70 region 3 Glyoxal_oxid_N PF07250.11 GAK63053.1 - 5.2e-29 101.1 2.5 1.7e-26 92.9 1.2 3.7 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAK63053.1 - 1.4e-21 76.6 0.1 2.8e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Reg_prop PF07494.11 GAK63053.1 - 0.13 12.6 1.0 26 5.5 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller Kelch_4 PF13418.6 GAK63053.1 - 0.13 12.3 4.1 10 6.2 0.1 4.6 5 0 0 5 5 5 0 Galactose oxidase, central domain CD99L2 PF12301.8 GAK63053.1 - 0.33 11.2 1.5 0.74 10.1 1.5 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 COX7a PF02238.15 GAK63054.1 - 3.8e-19 68.8 0.5 5e-19 68.5 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII TrmO_C PF18389.1 GAK63054.1 - 0.02 15.0 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 TrmO C-terminal domain Maf PF02545.14 GAK63055.1 - 2.2e-43 148.0 0.0 6.3e-43 146.5 0.0 1.7 2 0 0 2 2 2 1 Maf-like protein DAO PF01266.24 GAK63055.1 - 8.4e-25 88.1 2.1 2.5e-24 86.5 2.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK63055.1 - 0.051 13.6 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding SMK-1 PF04802.15 GAK63056.1 - 1.5e-75 253.3 1.0 2.8e-75 252.4 1.0 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 HEAT_2 PF13646.6 GAK63056.1 - 0.036 14.5 0.2 0.1 13.0 0.2 1.8 1 0 0 1 1 1 0 HEAT repeats RICTOR_N PF14664.6 GAK63056.1 - 0.11 11.4 0.3 0.21 10.5 0.3 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term RRN3 PF05327.11 GAK63056.1 - 1.6 7.2 5.2 4.6 5.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.32 GAK63057.1 - 2.7e-38 129.3 22.9 0.0042 17.9 0.1 11.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 GAK63057.1 - 9.5e-20 70.9 0.5 1.8e-19 70.0 0.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAK63057.1 - 2.3e-19 69.5 0.4 0.00038 20.7 0.0 7.1 5 3 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK63057.1 - 8.3e-09 34.6 0.6 0.027 13.2 0.0 6.1 5 2 1 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAK63057.1 - 1.3e-06 27.7 0.2 1.3 7.9 0.0 5.3 7 0 0 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 GAK63057.1 - 0.025 13.5 1.2 4.2 6.2 0.2 2.7 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Utp21 PF04192.12 GAK63057.1 - 0.033 13.7 1.3 0.09 12.3 0.1 2.0 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain PQQ_3 PF13570.6 GAK63057.1 - 0.45 11.1 2.1 6.6 7.4 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain N_BRCA1_IG PF16158.5 GAK63058.1 - 0.037 14.7 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene FOXP-CC PF16159.5 GAK63058.1 - 4.5 8.0 6.1 14 6.4 6.0 2.0 1 1 0 1 1 1 0 FOXP coiled-coil domain Glyco_transf_15 PF01793.16 GAK63059.1 - 1.9e-117 392.2 3.3 2.4e-117 391.8 3.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DASH_Dad1 PF08649.10 GAK63060.1 - 0.029 14.6 1.2 0.44 10.8 0.1 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad1 Glyco_H_20C_C PF18088.1 GAK63060.1 - 0.034 14.0 2.1 0.074 12.9 2.1 1.5 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain DIOX_N PF14226.6 GAK63061.1 - 1.1e-20 74.6 0.0 2.1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAK63061.1 - 1.4e-18 67.2 0.0 4.9e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tape_meas_lam_C PF09718.10 GAK63061.1 - 0.11 12.6 0.1 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3419 PF11899.8 GAK63062.1 - 8.3e-146 486.1 0.0 1.2e-145 485.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 GAK63062.1 - 5.9e-11 42.9 0.0 6.2e-10 39.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK63062.1 - 4.7e-10 40.0 0.0 3.5e-07 30.8 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK63062.1 - 5.5e-09 35.7 0.0 1.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAK63062.1 - 2e-08 34.2 0.0 6.4e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK63062.1 - 2.8e-07 30.5 0.0 1.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK63062.1 - 3.3e-07 31.0 0.0 8.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAK63062.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 GAK63062.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain SRP68 PF16969.5 GAK63063.1 - 1.9e-54 185.6 44.6 1.5e-46 159.6 31.6 3.2 2 1 0 2 2 2 2 RNA-binding signal recognition particle 68 Sugar_tr PF00083.24 GAK63065.1 - 1.2e-98 330.9 15.9 1.8e-55 188.7 3.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAK63065.1 - 2.2e-26 92.7 31.9 3e-26 92.2 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAK63065.1 - 0.00019 20.0 3.0 0.00035 19.1 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 GAK63065.1 - 0.059 13.9 8.9 0.031 14.8 5.2 2.5 2 0 0 2 2 2 0 Phage holin family 2 Pex19 PF04614.12 GAK63065.1 - 0.16 11.7 1.0 0.26 11.0 1.0 1.2 1 0 0 1 1 1 0 Pex19 protein family SNARE_assoc PF09335.11 GAK63066.1 - 1.2e-08 35.5 11.1 1.4e-08 35.3 6.3 2.8 3 1 0 3 3 3 1 SNARE associated Golgi protein MacB_PCD PF12704.7 GAK63066.1 - 0.00031 21.2 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 MacB-like periplasmic core domain CPP1-like PF11833.8 GAK63066.1 - 0.032 13.9 2.3 0.83 9.3 0.1 3.1 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sld5 PF05916.11 GAK63067.1 - 7.9e-20 71.4 0.0 1.4e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein RhoGAP PF00620.27 GAK63068.1 - 6.8e-39 133.1 0.0 1.4e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 GAK63068.1 - 3e-12 46.7 0.0 2e-11 44.0 0.0 2.5 2 1 0 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.19 GAK63068.1 - 8.4e-12 45.6 0.0 2.7e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain PH PF00169.29 GAK63068.1 - 4.4e-07 30.4 0.0 0.0037 17.8 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 GAK63068.1 - 7.3e-07 29.6 0.0 2.1e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Trypan_PARP PF05887.11 GAK63068.1 - 0.00029 20.8 2.3 0.00029 20.8 2.3 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 GAK63068.1 - 0.15 11.2 5.1 0.32 10.1 5.1 1.5 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 AMP-binding PF00501.28 GAK63069.1 - 3.8e-91 305.8 0.0 5.6e-91 305.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK63069.1 - 1.2e-13 51.9 1.9 1.2e-13 51.9 1.9 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SnoaL PF07366.12 GAK63070.1 - 5.5e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAK63070.1 - 1.6e-05 25.4 0.1 5.7e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain Peptidase_S66 PF02016.15 GAK63070.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain CDC50 PF03381.15 GAK63071.1 - 1.9e-90 303.2 0.3 2.5e-90 302.8 0.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RabGAP-TBC PF00566.18 GAK63072.1 - 4.7e-24 85.2 0.0 2.2e-19 70.0 0.0 2.9 2 1 0 2 2 2 2 Rab-GTPase-TBC domain PRIMA1 PF16101.5 GAK63072.1 - 1.8 8.7 7.2 1.8 8.6 3.4 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ATG_C PF09333.11 GAK63074.1 - 2.9e-27 94.8 0.3 9.7e-27 93.2 0.3 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 GAK63074.1 - 1.6e-16 60.4 0.0 4.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 GAK63074.1 - 1.5e-14 54.1 0.0 7.5e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 GAK63074.1 - 0.0059 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal HsbA PF12296.8 GAK63074.1 - 0.039 14.4 0.7 0.19 12.1 0.1 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A bZIP_C PF12498.8 GAK63074.1 - 6.3 7.8 5.7 3.7 8.5 0.0 3.0 3 0 0 3 3 3 0 Basic leucine-zipper C terminal Cellulase PF00150.18 GAK63075.1 - 9.8e-14 51.4 16.9 3.1e-13 49.8 16.9 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1188 PF06690.11 GAK63076.1 - 0.15 11.5 0.4 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) AAR2 PF05282.11 GAK63078.1 - 3.2e-74 250.4 0.0 3.8e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Sec7 PF01369.20 GAK63079.1 - 1.9e-64 216.7 0.0 3.3e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAK63079.1 - 1.1e-17 64.4 0.0 1.1e-16 61.2 0.0 2.7 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Spt20 PF12090.8 GAK63079.1 - 0.69 9.5 4.0 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Spt20 family FAD_binding_2 PF00890.24 GAK63080.1 - 2.1e-126 422.4 3.1 2.7e-126 422.0 3.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAK63080.1 - 1.9e-44 150.8 0.7 2.9e-44 150.2 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 GAK63080.1 - 1.4e-05 24.4 1.1 0.037 13.1 1.9 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 GAK63080.1 - 5.5e-05 22.5 0.5 0.012 14.9 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 GAK63080.1 - 0.0054 16.0 0.2 0.011 15.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAK63080.1 - 0.0076 15.5 1.0 0.022 14.0 0.3 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK63080.1 - 0.03 13.9 1.4 0.2 11.2 1.4 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAK63080.1 - 0.19 10.4 2.6 0.7 8.5 0.5 2.7 3 0 0 3 3 3 0 HI0933-like protein KTI12 PF08433.10 GAK63081.1 - 6.8e-60 202.8 0.0 1.2e-59 202.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAK63081.1 - 2.4e-06 27.8 0.0 5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 GAK63082.1 - 1.3e-51 174.8 0.0 2e-50 171.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK63082.1 - 2.6e-27 95.4 0.0 3.2e-26 91.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK63082.1 - 0.0027 17.7 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HeLo PF14479.6 GAK63082.1 - 0.19 11.5 2.5 0.49 10.2 0.8 2.6 2 0 0 2 2 2 0 Prion-inhibition and propagation PAP_assoc PF03828.19 GAK63083.1 - 5.1e-21 74.6 0.0 1.3e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAK63083.1 - 6.8e-10 39.1 0.0 1.6e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1664 PF07889.12 GAK63084.1 - 0.068 13.2 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BORCS7 PF16088.5 GAK63084.1 - 0.072 13.4 0.2 0.072 13.4 0.2 1.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 tRNA-synt_2d PF01409.20 GAK63085.1 - 9.4e-47 159.5 0.0 5.7e-26 91.5 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GAK63085.1 - 2.9e-24 85.3 0.1 7e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DOCK_N PF16172.5 GAK63086.1 - 1.2e-112 376.6 0.0 2.8e-112 375.4 0.0 1.6 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 GAK63086.1 - 3.1e-71 240.6 0.0 6.2e-71 239.6 0.0 1.5 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GAK63086.1 - 2.6e-51 174.2 0.0 6.9e-51 172.8 0.0 1.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Pkinase PF00069.25 GAK63089.1 - 3.4e-63 213.5 0.0 4e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63089.1 - 6.2e-19 68.3 0.0 8.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK63089.1 - 3.1e-07 30.6 0.0 3.5e-06 27.1 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAK63089.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAK63089.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 GAK63089.1 - 0.049 13.2 0.2 0.049 13.2 0.2 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2456 PF10445.9 GAK63090.1 - 1e-18 67.2 6.9 1e-18 67.2 6.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2456) LrgB PF04172.16 GAK63090.1 - 0.057 12.9 0.5 0.11 12.0 0.5 1.4 1 0 0 1 1 1 0 LrgB-like family RRM_1 PF00076.22 GAK63091.1 - 1.2e-48 162.8 0.0 6.1e-20 70.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK63091.1 - 1.3e-07 31.2 0.0 0.0001 21.9 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAK63091.1 - 0.097 12.5 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif SNF2_N PF00176.23 GAK63094.1 - 1.4e-74 250.9 1.8 2.9e-74 249.9 1.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK63094.1 - 4.9e-21 75.1 0.2 3.3e-19 69.3 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 GAK63094.1 - 3.4e-20 72.1 7.3 3.4e-20 72.1 7.3 3.6 3 0 0 3 3 3 1 HSA Bromodomain PF00439.25 GAK63094.1 - 3.8e-15 55.7 0.0 1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 GAK63094.1 - 3.8e-14 52.1 1.4 1.2e-13 50.6 1.4 1.8 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 GAK63094.1 - 3.6e-13 49.9 2.7 3.6e-13 49.9 2.7 3.6 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 GAK63094.1 - 9.5e-11 42.0 0.1 5.5e-10 39.5 0.1 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAK63094.1 - 3.1e-05 23.7 0.0 0.00011 22.0 0.0 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase RNA_pol_L_2 PF13656.6 GAK63095.1 - 2.9e-26 91.0 0.0 4.4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAK63095.1 - 1.5e-07 30.8 0.0 5.3e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain K_channel_TID PF07941.11 GAK63095.1 - 4.6 7.8 19.2 7.7 7.0 3.4 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TFIIS_M PF07500.14 GAK63096.1 - 8.3e-24 84.2 0.1 1.1e-23 83.9 0.1 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain DUF218 PF02698.17 GAK63097.1 - 5.5e-05 23.2 0.0 0.042 13.9 0.0 2.3 1 1 1 2 2 2 2 DUF218 domain DUF726 PF05277.12 GAK63097.1 - 0.053 12.4 0.1 0.077 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) IMUP PF15761.5 GAK63097.1 - 0.55 10.9 5.9 0.95 10.2 5.9 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Usp PF00582.26 GAK63098.1 - 6.2e-21 75.4 0.1 8.4e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family Toprim_4 PF13662.6 GAK63098.1 - 0.00012 22.4 0.1 0.0025 18.3 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Toprim PF01751.22 GAK63098.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Toprim domain DUF3253 PF11625.8 GAK63098.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Ph1570 PF09638.10 GAK63098.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Ph1570 protein ING PF12998.7 GAK63099.1 - 2.9e-10 40.6 0.1 5.2e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAK63099.1 - 1.5e-05 24.7 6.8 2.5e-05 24.1 6.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAK63099.1 - 0.27 11.5 1.2 0.52 10.6 1.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 GAK63099.1 - 0.32 10.6 2.6 0.55 9.8 2.6 1.3 1 0 0 1 1 1 0 PHD-finger PPP4R2 PF09184.11 GAK63099.1 - 4.3 6.9 14.1 6.9 6.2 14.1 1.4 1 0 0 1 1 1 0 PPP4R2 EF1_GNE PF00736.19 GAK63100.1 - 2.2e-30 104.7 1.5 2.2e-30 104.7 1.5 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 GAK63100.1 - 2e-13 50.5 3.6 2e-13 50.5 3.6 2.3 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 GAK63100.1 - 0.0067 16.4 0.2 0.06 13.4 0.2 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAK63100.1 - 0.064 13.5 0.2 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAK63100.1 - 0.087 13.0 0.6 0.29 11.4 0.1 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DNA_ligase_OB_2 PF14743.6 GAK63101.1 - 1.4e-06 28.2 0.2 3.4e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 GAK63101.1 - 2.8e-06 27.1 0.0 1.5e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain ORC5_C PF14630.6 GAK63102.1 - 3.3e-76 256.5 1.4 5.2e-76 255.9 1.4 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF3292 PF11696.8 GAK63103.1 - 3e-225 749.5 0.0 3e-134 448.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Arylesterase PF01731.20 GAK63104.1 - 0.021 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Arylesterase CDC50 PF03381.15 GAK63104.1 - 0.15 11.6 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family SBBP PF06739.11 GAK63104.1 - 0.54 10.3 2.6 0.62 10.1 0.5 2.2 2 0 0 2 2 2 0 Beta-propeller repeat Trypsin_2 PF13365.6 GAK63105.1 - 2.1e-05 25.4 3.3 0.049 14.5 2.7 2.5 1 1 0 2 2 2 2 Trypsin-like peptidase domain MRP-L20 PF12824.7 GAK63106.1 - 4.2e-29 101.8 2.5 1.9e-28 99.7 2.2 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.14 GAK63106.1 - 6e-11 42.1 0.0 2e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAK63106.1 - 0.027 14.5 0.1 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 GAK63106.1 - 0.031 13.9 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Bap31_Bap29_C PF18035.1 GAK63106.1 - 0.042 13.9 0.4 0.12 12.4 0.4 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain FAD_binding_3 PF01494.19 GAK63106.1 - 0.17 11.1 0.1 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain MCRA PF06100.11 GAK63106.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 MCRA family DUF3818 PF12825.7 GAK63107.1 - 6.4e-133 443.0 0.0 9.1e-133 442.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 GAK63107.1 - 6.5e-42 142.6 1.5 1.5e-41 141.4 1.5 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 GAK63107.1 - 1.4e-06 28.3 0.0 8.4e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 PX domain TetR_C_26 PF17934.1 GAK63107.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4611 PF15387.6 GAK63107.1 - 0.084 13.1 2.1 0.67 10.2 2.1 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Aminotran_1_2 PF00155.21 GAK63108.1 - 2.1e-38 132.5 0.0 2.9e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DeoC PF01791.9 GAK63109.1 - 9.7e-21 74.5 3.1 1.3e-20 74.0 3.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 GAK63109.1 - 0.0048 16.4 0.2 0.054 13.0 0.1 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein TPR_12 PF13424.6 GAK63110.1 - 0.016 15.5 0.0 34 4.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAK63110.1 - 0.046 13.6 1.1 1.6 8.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MOZ_SAS PF01853.18 GAK63111.1 - 8.8e-61 204.7 0.0 3e-58 196.4 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 GAK63111.1 - 7.3e-16 57.5 1.9 2e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 GAK63111.1 - 1.1e-09 38.0 0.0 2.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Methyltransf_11 PF08241.12 GAK63112.1 - 7.4e-13 49.0 0.0 2e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK63112.1 - 1.3e-12 48.3 0.0 3.3e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK63112.1 - 3.8e-11 43.6 0.0 9.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK63112.1 - 1.1e-10 41.6 0.0 3.2e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 GAK63112.1 - 4e-07 30.0 0.0 6.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 GAK63112.1 - 1e-05 25.4 0.0 2.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAK63112.1 - 0.17 11.4 0.0 1.7 8.2 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase small domain DREV PF05219.12 GAK63112.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CAP PF00188.26 GAK63113.1 - 6.6e-24 85.2 5.9 6.6e-24 85.2 5.9 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family zf-U1 PF06220.12 GAK63113.1 - 0.11 12.3 2.7 0.3 10.9 2.7 1.7 1 0 0 1 1 1 0 U1 zinc finger Collagen PF01391.18 GAK63113.1 - 0.13 12.0 6.7 0.11 12.2 2.7 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Macoilin PF09726.9 GAK63113.1 - 0.58 8.7 7.2 0.62 8.5 7.2 1.0 1 0 0 1 1 1 0 Macoilin family Band_3_cyto PF07565.13 GAK63113.1 - 2.3 7.9 4.0 3.2 7.5 4.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM199X PF15814.5 GAK63113.1 - 5.2 6.0 15.8 9 5.2 15.8 1.4 1 0 0 1 1 1 0 Protein family FAM199X E1-E2_ATPase PF00122.20 GAK63114.1 - 8.5e-49 165.5 1.2 3e-48 163.7 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAK63114.1 - 1.9e-20 74.1 2.5 5.2e-20 72.6 2.5 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK63114.1 - 3.7e-11 42.5 0.0 8.6e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAK63114.1 - 0.0005 19.9 0.1 0.002 17.9 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TMEM132D_C PF15706.5 GAK63114.1 - 0.0041 16.8 0.6 1.5 8.7 0.0 3.1 3 0 0 3 3 3 2 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Cation_ATPase PF13246.6 GAK63114.1 - 0.11 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF1977 PF09320.11 GAK63116.1 - 4.5e-24 84.7 0.3 7.6e-24 84.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 GAK63116.1 - 8.4e-24 83.5 0.1 1.7e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain UQ_con PF00179.26 GAK63117.1 - 8.1e-51 171.4 0.0 9.4e-51 171.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAK63117.1 - 0.0025 17.5 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAK63117.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 1 0 1 1 1 0 RWD domain HSP70 PF00012.20 GAK63118.1 - 4.1e-260 864.1 8.1 4.7e-260 863.9 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAK63118.1 - 1.7e-12 46.8 7.9 8e-12 44.6 0.9 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 GAK63118.1 - 0.00061 20.2 5.6 0.12 12.8 0.2 3.8 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 GAK63118.1 - 0.0062 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Tex_YqgF PF16921.5 GAK63118.1 - 0.26 11.8 3.9 0.29 11.6 1.6 2.1 1 1 1 2 2 2 0 Tex protein YqgF-like domain MAS20 PF02064.15 GAK63119.1 - 6.5e-39 133.0 0.5 6.5e-39 133.0 0.5 2.2 2 0 0 2 2 2 1 MAS20 protein import receptor PI3K_1B_p101 PF10486.9 GAK63119.1 - 0.016 13.0 0.8 0.029 12.2 0.8 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GAPT PF11770.8 GAK63119.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) GOLD_2 PF13897.6 GAK63119.1 - 1.5 9.4 3.2 26 5.3 0.0 2.7 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Bmt2 PF11968.8 GAK63120.1 - 3.8e-72 242.7 0.0 5.3e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 GAK63120.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain ETF_QO PF05187.13 GAK63121.1 - 1e-42 144.5 0.1 1.6e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 GAK63121.1 - 3.7e-07 29.6 0.5 1.6e-05 24.2 0.7 2.2 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAK63121.1 - 3.4e-06 27.2 0.0 1.9e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK63121.1 - 4.1e-06 26.6 0.8 0.00018 21.2 0.8 2.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAK63121.1 - 2.5e-05 23.2 0.5 3.8e-05 22.6 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAK63121.1 - 4.2e-05 22.9 0.0 6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK63121.1 - 5.4e-05 22.5 0.0 0.00028 20.2 0.3 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 GAK63121.1 - 0.00013 21.3 1.1 0.0002 20.7 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAK63121.1 - 0.00037 19.7 0.1 0.00059 19.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAK63121.1 - 0.0022 17.3 0.3 0.0039 16.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAK63121.1 - 0.004 16.5 0.3 0.0064 15.9 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK63121.1 - 0.0067 16.4 0.9 0.013 15.5 0.3 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAK63121.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GAK63121.1 - 0.029 13.2 0.7 0.054 12.3 0.7 1.4 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 GAK63121.1 - 0.032 13.3 0.3 0.048 12.7 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_7 PF12838.7 GAK63121.1 - 0.041 14.5 1.6 0.086 13.4 1.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAK63121.1 - 2.4 8.4 5.1 0.25 11.5 0.5 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain Barwin PF00967.17 GAK63122.1 - 6.7e-08 32.4 0.2 0.00024 20.9 0.1 2.7 2 0 0 2 2 2 2 Barwin family DPBB_1 PF03330.18 GAK63122.1 - 0.00071 19.8 0.1 0.0034 17.6 0.1 2.3 2 1 0 2 2 2 1 Lytic transglycolase FIT1_2 PF17357.2 GAK63122.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.7 2 1 0 2 2 2 0 Facilitor Of iron transport 1 and 2 SOG2 PF10428.9 GAK63122.1 - 0.15 11.3 8.5 0.17 11.0 8.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Spt20 PF12090.8 GAK63122.1 - 0.21 11.2 7.0 0.29 10.7 7.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF4718 PF15842.5 GAK63122.1 - 0.28 11.0 2.1 0.47 10.2 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF908 PF06012.12 GAK63122.1 - 0.93 8.8 7.5 1.2 8.5 7.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MAP65_ASE1 PF03999.12 GAK63122.1 - 2.6 6.6 8.4 3.3 6.3 8.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Hamartin PF04388.12 GAK63122.1 - 5.2 5.6 7.4 6.9 5.2 7.4 1.1 1 0 0 1 1 1 0 Hamartin protein FYVE PF01363.21 GAK63123.1 - 1.7e-21 76.1 2.4 2.9e-21 75.4 2.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 GAK63123.1 - 3.1e-13 49.2 0.4 8.1e-13 47.9 0.4 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Paf67 PF10255.9 GAK63125.1 - 4.8e-169 562.6 0.1 7.5e-169 562.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Ribosomal_60s PF00428.19 GAK63125.1 - 0.075 13.6 0.2 0.075 13.6 0.2 4.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein TPR_2 PF07719.17 GAK63125.1 - 0.11 12.7 3.0 0.19 11.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat EPL1 PF10513.9 GAK63126.1 - 0.46 10.8 22.2 0.36 11.2 5.9 3.3 2 0 0 2 2 2 0 Enhancer of polycomb-like ABC1 PF03109.16 GAK63127.1 - 2.7e-22 79.2 0.0 5.6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 GAK63127.1 - 0.16 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family SRF-TF PF00319.18 GAK63128.1 - 2.7e-20 71.6 0.0 4.3e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.14 GAK63128.1 - 0.0013 17.1 10.6 0.043 12.1 1.0 2.1 2 0 0 2 2 2 2 CDC45-like protein Sporozoite_P67 PF05642.11 GAK63128.1 - 0.98 7.4 26.5 1.6 6.8 14.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Spt5_N PF11942.8 GAK63128.1 - 8.3 7.5 22.1 0.064 14.2 3.2 3.6 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.25 GAK63130.1 - 4.5e-12 45.9 0.0 7.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAK63130.1 - 1.5e-05 25.0 1.9 0.0004 20.4 0.2 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAK63130.1 - 6e-05 22.3 0.0 8.7e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 GAK63130.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 GAK63130.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAK63130.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 GAK63130.1 - 0.28 9.9 2.1 0.55 9.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase TMEM214 PF10151.9 GAK63130.1 - 8.3 4.7 8.0 12 4.2 8.0 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Mito_carr PF00153.27 GAK63131.1 - 5.4e-61 202.5 6.7 1e-21 76.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 GAK63131.1 - 0.018 14.6 1.9 0.11 12.1 0.1 3.1 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.6 GAK63131.1 - 0.019 14.9 0.1 0.08 12.9 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain SCHIP-1 PF10148.9 GAK63131.1 - 1.3 8.6 4.0 57 3.2 0.0 2.6 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 Tubulin PF00091.25 GAK63132.1 - 6.4e-67 225.6 0.0 8.5e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAK63132.1 - 7.5e-47 158.6 0.0 1.1e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAK63132.1 - 0.00037 20.2 0.0 0.00099 18.8 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain PTP_tm PF18861.1 GAK63132.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Tubulin_2 PF13809.6 GAK63132.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin like RNB PF00773.19 GAK63133.1 - 1e-105 353.7 0.2 2.2e-105 352.6 0.0 1.6 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 GAK63133.1 - 1.8e-23 82.6 0.1 4.7e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 GAK63133.1 - 4.4e-21 74.7 0.0 9.2e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 GAK63133.1 - 5.6e-05 22.9 0.4 0.007 16.1 0.0 2.4 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 GAK63133.1 - 0.033 14.1 0.4 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 S1 domain DUF3881 PF12997.7 GAK63133.1 - 0.06 12.6 0.3 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) DEAD PF00270.29 GAK63134.1 - 7.7e-41 139.8 0.0 1.6e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK63134.1 - 5.8e-25 87.8 0.0 2e-23 82.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 GAK63134.1 - 2.1e-21 75.9 0.7 2.1e-21 75.9 0.7 3.4 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ResIII PF04851.15 GAK63134.1 - 1.1e-05 25.5 0.0 3.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vps53_N PF04100.12 GAK63136.1 - 7.2e-92 308.3 0.3 1.3e-91 307.5 0.3 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 GAK63136.1 - 0.0035 16.7 5.7 0.006 15.9 5.7 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 GAK63136.1 - 0.016 13.8 1.5 0.043 12.4 1.5 1.7 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 NBD94 PF16830.5 GAK63136.1 - 0.08 13.3 0.4 0.2 12.1 0.4 1.6 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH DUF5394 PF17372.2 GAK63136.1 - 0.12 11.9 2.5 0.22 11.0 2.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5394) Fib_alpha PF08702.10 GAK63136.1 - 0.97 9.6 7.2 1.4 9.1 5.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 GAK63136.1 - 4 7.5 7.4 4.5 7.3 4.8 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 GAK63136.1 - 6 6.9 9.2 3.1 7.8 5.7 2.4 2 0 0 2 2 2 0 FlxA-like protein MnmE_helical PF12631.7 GAK63136.1 - 9.4 6.3 9.3 28 4.8 9.3 1.9 1 1 0 1 1 1 0 MnmE helical domain HMMR_C PF15908.5 GAK63137.1 - 0.00032 21.0 6.5 0.00032 21.0 6.5 6.4 2 2 5 7 7 7 2 Hyaluronan mediated motility receptor C-terminal DUF4407 PF14362.6 GAK63137.1 - 0.00044 19.7 19.3 0.00044 19.7 19.3 5.5 1 1 4 5 5 5 2 Domain of unknown function (DUF4407) PIG-P PF08510.12 GAK63138.1 - 9.2e-33 112.7 1.4 1.3e-32 112.2 1.4 1.2 1 0 0 1 1 1 1 PIG-P CIA30 PF08547.12 GAK63138.1 - 1.4e-14 54.5 0.0 3.4e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) DPM2 PF07297.12 GAK63138.1 - 0.029 14.6 3.9 0.056 13.7 3.9 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HIT PF01230.23 GAK63139.1 - 9.1e-20 71.2 1.4 1.5e-19 70.6 0.6 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 GAK63139.1 - 1e-14 55.0 0.1 1.7e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAK63139.1 - 2.2e-06 27.5 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rax2 PF12768.7 GAK63141.1 - 3.6e-41 141.0 0.1 3e-38 131.5 0.0 4.1 4 0 0 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 GAK63141.1 - 3e-13 49.1 0.0 7.4e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK63141.1 - 1.2e-11 44.2 0.1 1e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAK63141.1 - 2e-06 27.4 0.0 5.5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 GAK63141.1 - 0.0027 17.9 2.0 0.28 11.5 0.1 4.9 5 1 1 6 6 5 1 Kelch motif SH3_10 PF17902.1 GAK63141.1 - 0.0053 16.8 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 SH3 domain DUF1918 PF08940.11 GAK63141.1 - 0.028 14.1 0.2 0.15 11.7 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) hSH3 PF14603.6 GAK63141.1 - 0.052 14.0 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain TilS PF09179.11 GAK63141.1 - 0.1 13.1 2.0 0.27 11.7 2.0 1.7 1 0 0 1 1 1 0 TilS substrate binding domain DUF5122 PF17164.4 GAK63141.1 - 0.12 12.7 0.1 0.12 12.7 0.1 7.7 8 0 0 8 8 8 0 Domain of unknown function (DUF5122) beta-propeller NCU-G1 PF15065.6 GAK63141.1 - 0.54 9.2 3.0 0.98 8.3 3.0 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Kelch_3 PF13415.6 GAK63141.1 - 9.8 6.6 11.5 1.6 9.1 0.1 5.0 6 0 0 6 6 6 0 Galactose oxidase, central domain Metallophos PF00149.28 GAK63142.1 - 1.4e-34 120.4 0.6 2.1e-34 119.8 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_carr PF00153.27 GAK63143.1 - 7.6e-08 32.2 0.0 0.034 14.1 0.0 3.4 3 0 0 3 3 3 2 Mitochondrial carrier protein Neisseria_TspB PF05616.13 GAK63145.1 - 3.3 6.1 7.2 4.6 5.6 7.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Ribosom_S12_S23 PF00164.25 GAK63147.1 - 5.3e-48 161.4 0.8 8.8e-48 160.7 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L27e PF01777.18 GAK63148.1 - 3e-38 130.0 3.2 4.6e-38 129.4 3.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family SecY PF00344.20 GAK63149.1 - 1.2e-73 248.1 6.4 1.5e-73 247.7 6.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAK63149.1 - 1.9e-17 62.8 0.2 6.7e-17 61.0 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.11 GAK63149.1 - 0.1 12.5 2.8 1.6 8.7 0.0 3.4 3 1 0 3 3 3 0 Tight junction protein, Claudin-like RNA_pol_N PF01194.17 GAK63150.1 - 3.5e-29 100.9 0.3 4.9e-29 100.4 0.3 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit BRE1 PF08647.11 GAK63151.1 - 1.6e-23 82.6 8.1 1.6e-23 82.6 8.1 8.1 5 1 2 8 8 8 2 BRE1 E3 ubiquitin ligase zf-RING_5 PF14634.6 GAK63151.1 - 5e-06 26.4 13.2 9e-06 25.6 13.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAK63151.1 - 2.4e-05 24.1 13.0 3.9e-05 23.4 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK63151.1 - 2.6e-05 24.0 10.0 4.6e-05 23.2 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK63151.1 - 5e-05 23.1 11.5 8.2e-05 22.4 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK63151.1 - 0.00015 21.7 7.4 0.00028 20.8 7.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Lebercilin PF15619.6 GAK63151.1 - 0.00085 19.0 17.4 0.00085 19.0 17.4 6.8 2 2 5 7 7 5 1 Ciliary protein causing Leber congenital amaurosis disease Prok-RING_4 PF14447.6 GAK63151.1 - 0.0021 17.9 7.7 0.0037 17.1 7.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Fez1 PF06818.15 GAK63151.1 - 0.0062 17.0 18.8 0.0062 17.0 18.8 5.1 1 1 3 4 4 4 2 Fez1 zf-RING_6 PF14835.6 GAK63151.1 - 0.0076 16.1 2.8 0.016 15.1 2.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 GAK63151.1 - 0.012 15.9 10.9 0.02 15.2 10.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 GAK63151.1 - 0.017 15.4 6.4 0.036 14.4 6.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ribbon_3 PF13248.6 GAK63151.1 - 0.21 11.1 0.9 0.73 9.3 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_5 PF17121.5 GAK63151.1 - 0.38 10.7 6.8 0.75 9.7 6.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vac_Fusion PF02346.16 GAK63151.1 - 0.65 9.7 3.8 3.6 7.3 0.3 3.7 3 0 0 3 3 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF1272 PF06906.11 GAK63151.1 - 1.3 9.2 4.7 3.2 7.9 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Filament PF00038.21 GAK63151.1 - 1.7 8.2 84.8 0.21 11.1 16.8 6.2 2 1 0 4 4 4 0 Intermediate filament protein DZR PF12773.7 GAK63151.1 - 2.5 8.2 7.2 4.6 7.3 7.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 GAK63151.1 - 2.8 8.2 8.2 5 7.4 8.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PKcGMP_CC PF16808.5 GAK63151.1 - 5.9 6.8 20.7 0.15 12.0 0.3 6.1 6 0 0 6 6 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2730 PF10805.8 GAK63151.1 - 7.1 6.8 22.2 0.078 13.1 1.9 5.9 2 1 2 5 5 5 0 Protein of unknown function (DUF2730) Pam17 PF08566.10 GAK63152.1 - 0.0032 17.3 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 TcdA_TcdB_pore PF12920.7 GAK63152.1 - 1.6 6.9 4.4 2.5 6.3 4.4 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain PWWP PF00855.17 GAK63153.1 - 3.6e-19 69.0 0.0 3.6e-19 69.0 0.0 2.8 3 1 0 3 3 3 1 PWWP domain Med26 PF08711.11 GAK63153.1 - 2.5e-08 33.8 0.0 6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nop14 PF04147.12 GAK63153.1 - 0.039 12.2 16.1 0.058 11.6 16.1 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GAK63153.1 - 0.34 10.2 6.8 0.72 9.1 6.8 1.5 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GAK63153.1 - 0.39 8.9 14.7 0.55 8.4 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GAK63153.1 - 0.57 8.3 10.5 0.78 7.8 10.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 GAK63153.1 - 1.1 9.2 2.7 1.8 8.6 2.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.9 GAK63153.1 - 2.6 8.1 18.4 0.45 10.6 14.5 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM76 PF16046.5 GAK63153.1 - 4.9 6.4 10.1 8.5 5.6 10.1 1.3 1 0 0 1 1 1 0 FAM76 protein TFIIA PF03153.13 GAK63154.1 - 6.1e-56 191.2 21.7 2.6e-35 123.2 18.1 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Tup_N PF08581.10 GAK63154.1 - 0.032 14.5 0.4 0.062 13.6 0.4 1.4 1 0 0 1 1 1 0 Tup N-terminal BUD22 PF09073.10 GAK63154.1 - 0.11 11.8 11.6 0.14 11.5 11.6 1.2 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 GAK63154.1 - 0.2 11.6 3.8 0.24 11.3 3.8 1.1 1 0 0 1 1 1 0 SPX domain DUF2967 PF11179.8 GAK63154.1 - 0.26 9.4 9.6 0.31 9.1 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) HSF_DNA-bind PF00447.17 GAK63155.1 - 3.8e-31 107.6 0.2 6e-31 106.9 0.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Brix PF04427.18 GAK63158.1 - 1.9e-44 152.1 0.1 2.5e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 GAK63158.1 - 0.034 12.7 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin MDD_C PF18376.1 GAK63159.1 - 9e-71 237.5 0.0 1.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GAK63159.1 - 1.7e-07 31.4 2.2 4.7e-07 29.9 2.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Sybindin PF04099.12 GAK63160.1 - 2.6e-06 27.4 0.0 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 2 Sybindin-like family EMP70 PF02990.16 GAK63161.1 - 5.2e-193 642.4 0.4 7.2e-193 642.0 0.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Serinc PF03348.15 GAK63162.1 - 1.4e-156 521.8 5.7 1.6e-156 521.6 5.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2214 PF09980.9 GAK63162.1 - 0.0072 16.1 0.6 0.0072 16.1 0.6 2.4 1 1 1 2 2 2 1 Predicted membrane protein (DUF2214) HXXEE PF13787.6 GAK63162.1 - 0.02 15.7 2.6 0.02 15.7 2.6 3.5 3 1 1 4 4 4 0 Protein of unknown function with HXXEE motif YtpI PF14007.6 GAK63162.1 - 0.069 13.3 6.7 0.21 11.7 3.6 2.8 2 0 0 2 2 2 0 YtpI-like protein DUF2431 PF10354.9 GAK63163.1 - 2.8e-40 138.3 0.0 4e-39 134.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) CCDC71L PF15374.6 GAK63163.1 - 0.74 9.0 6.0 1.8 7.7 6.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L TPR_1 PF00515.28 GAK63165.1 - 3.3e-22 77.3 2.6 0.00018 21.2 0.0 7.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAK63165.1 - 6.8e-18 63.3 9.9 0.0034 17.4 0.1 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAK63165.1 - 1.1e-17 63.9 15.6 5.7e-08 32.8 0.8 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat DnaJ PF00226.31 GAK63165.1 - 1.2e-17 63.7 0.0 4.7e-17 61.9 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 GAK63165.1 - 1.3e-16 60.8 27.9 2.1e-06 28.1 2.2 6.6 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAK63165.1 - 8.4e-14 50.6 7.8 0.0072 16.4 0.5 6.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAK63165.1 - 1.7e-13 50.9 13.8 1.1e-06 29.2 2.7 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAK63165.1 - 2.7e-12 46.4 19.1 0.025 15.4 0.1 7.5 4 3 4 8 8 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAK63165.1 - 1.1e-10 41.2 10.2 0.033 14.6 0.1 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAK63165.1 - 3.4e-10 39.4 0.5 0.007 16.0 0.3 5.1 3 2 2 5 5 5 2 TPR repeat ANAPC3 PF12895.7 GAK63165.1 - 4.8e-09 36.3 9.7 0.0014 18.8 0.4 4.8 3 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAK63165.1 - 3.7e-06 27.1 13.6 0.029 14.7 2.6 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAK63165.1 - 5e-06 26.8 20.8 0.041 14.5 0.2 7.6 8 2 0 8 8 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAK63165.1 - 4e-05 23.6 2.1 6.6 6.9 0.0 5.2 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 GAK63165.1 - 0.00039 20.3 8.0 17 5.7 0.0 6.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAK63165.1 - 0.00047 20.4 18.1 0.022 15.1 1.3 5.4 4 1 0 5 5 4 1 Tetratricopeptide repeat PknG_TPR PF16918.5 GAK63165.1 - 0.0036 16.1 7.7 0.052 12.3 0.1 3.5 2 1 0 3 3 3 1 Protein kinase G tetratricopeptide repeat DUF3856 PF12968.7 GAK63165.1 - 0.0086 16.2 1.5 5.9 7.0 0.2 3.6 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 GAK63165.1 - 0.01 15.3 0.2 0.01 15.3 0.2 2.7 3 0 0 3 3 3 0 SHNi-TPR DUF357 PF04010.13 GAK63165.1 - 0.094 12.8 0.6 4.7 7.4 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) BTAD PF03704.17 GAK63165.1 - 0.11 12.9 0.3 0.11 12.9 0.3 3.8 3 1 2 5 5 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 GAK63165.1 - 0.11 13.1 8.4 28 5.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat UPF0254 PF06787.11 GAK63165.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Spectrin PF00435.21 GAK63165.1 - 0.26 11.8 10.0 0.86 10.1 1.7 4.2 3 2 0 3 3 3 0 Spectrin repeat PIN_4 PF13638.6 GAK63166.1 - 4.9e-18 65.7 0.1 1.6e-17 64.0 0.1 2.0 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 GAK63166.1 - 6e-13 48.9 0.0 1.9e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 GAK63166.1 - 0.0028 18.0 0.8 0.13 12.5 0.0 3.0 2 0 0 2 2 2 1 PIN like domain DUF2802 PF10975.8 GAK63166.1 - 0.36 11.0 3.3 1.4 9.1 3.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Pterin_bind PF00809.22 GAK63167.1 - 6.9e-77 258.4 2.4 3.6e-75 252.8 2.4 2.5 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 GAK63167.1 - 5.7e-50 168.5 5.7 2.8e-24 85.8 1.3 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 GAK63167.1 - 8.9e-37 126.0 0.0 2.6e-36 124.5 0.0 1.9 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 2-Hacid_dh_C PF02826.19 GAK63170.1 - 2.7e-46 157.2 0.0 3.9e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAK63170.1 - 4.2e-21 75.0 0.0 6.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 GAK63170.1 - 0.006 16.7 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase SNF2_N PF00176.23 GAK63171.1 - 3.4e-51 174.0 0.0 5.9e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK63171.1 - 1.1e-15 57.9 0.1 5.3e-15 55.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK63171.1 - 8.9e-08 32.3 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAK63171.1 - 9.4e-07 28.3 0.0 1.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 GAK63171.1 - 0.051 13.8 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif BC10 PF06726.12 GAK63172.1 - 8.7e-19 67.5 7.9 1.9e-18 66.4 7.9 1.6 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Bromodomain PF00439.25 GAK63173.1 - 7.3e-26 90.1 0.0 1.5e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GAK63173.1 - 1.4e-07 31.7 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAK63173.1 - 2.5e-06 27.5 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK63173.1 - 0.00023 21.5 0.1 0.00044 20.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAM196 PF15265.6 GAK63173.1 - 2.6 7.4 10.0 4.2 6.8 10.0 1.3 1 0 0 1 1 1 0 FAM196 family ANTH PF07651.16 GAK63174.1 - 1.1e-50 172.3 0.0 1.6e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 GAK63174.1 - 1.7e-05 24.9 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain AMP-binding PF00501.28 GAK63175.1 - 1e-222 739.2 0.0 3.9e-79 266.2 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAK63175.1 - 9.9e-104 347.5 0.0 5.1e-30 104.6 0.0 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 GAK63175.1 - 2e-39 133.7 0.6 1.9e-09 37.8 0.0 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAK63175.1 - 1.4e-12 48.4 0.1 0.00016 22.6 0.0 4.1 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 GAK63175.1 - 0.049 12.3 0.0 2.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Transferase family K_oxygenase PF13434.6 GAK63176.1 - 6.6e-87 291.8 0.0 2.2e-86 290.1 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAK63176.1 - 1.9e-05 24.7 1.0 0.0019 18.2 0.1 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAK63176.1 - 0.15 11.3 0.0 2.2 7.5 0.0 2.4 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCCH PF00642.24 GAK63177.1 - 5e-09 35.9 2.7 5e-09 35.9 2.7 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 GAK63177.1 - 1.1e-07 31.7 4.0 2.3e-07 30.7 4.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAK63177.1 - 3e-07 30.2 4.6 6e-07 29.2 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK63177.1 - 1.9e-06 27.7 8.1 3.4e-06 26.9 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAK63177.1 - 7.7e-06 25.7 7.3 1.5e-05 24.7 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 GAK63177.1 - 1.7e-05 24.7 4.4 3.1e-05 23.9 4.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 GAK63177.1 - 3.4e-05 24.1 5.5 6.7e-05 23.1 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAK63177.1 - 0.0001 22.1 7.2 0.00019 21.2 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAK63177.1 - 0.00031 20.8 5.8 0.00069 19.7 5.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 GAK63177.1 - 0.002 18.2 2.2 0.002 18.2 2.2 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 GAK63177.1 - 0.0026 17.6 4.8 0.0048 16.7 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 GAK63177.1 - 0.0031 17.3 2.9 0.0031 17.3 2.9 1.8 2 0 0 2 2 1 1 CCCH-type zinc finger zf-Nse PF11789.8 GAK63177.1 - 0.061 13.2 1.9 0.12 12.2 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TFIIF_alpha PF05793.12 GAK63177.1 - 0.6 8.6 7.0 0.85 8.1 7.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GATase_5 PF13507.6 GAK63178.1 - 5.4e-92 307.5 0.0 8.6e-92 306.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 GAK63178.1 - 9.5e-41 139.5 3.7 4.6e-25 88.6 0.1 2.7 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GAK63178.1 - 1.2e-34 118.8 0.0 2.2e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GAK63178.1 - 2.3e-22 79.3 0.0 6e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 GAK63178.1 - 0.56 10.9 5.3 2.5 8.8 0.0 3.5 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain Phosducin PF02114.16 GAK63179.1 - 9.6e-22 77.2 0.1 9.3e-21 73.9 0.1 2.2 1 1 0 1 1 1 1 Phosducin GREB1 PF15782.5 GAK63179.1 - 0.11 9.6 3.4 0.14 9.2 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YliH PF10799.8 GAK63179.1 - 0.15 12.0 5.1 2.1 8.3 1.2 2.8 3 1 0 3 3 3 0 Biofilm formation protein (YliH/bssR) tRNA-synt_1 PF00133.22 GAK63180.1 - 1.6e-223 743.4 0.0 2e-223 743.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAK63180.1 - 4.7e-22 78.6 0.0 9.2e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAK63180.1 - 4.8e-14 51.9 1.1 8.7e-05 21.4 0.2 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAK63180.1 - 0.0014 18.0 0.0 0.0046 16.3 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.8 GAK63181.1 - 1.4e-05 25.2 0.0 2.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 GAK63181.1 - 7e-05 22.8 0.6 0.00019 21.4 0.6 1.8 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-met PF12874.7 GAK63181.1 - 0.00012 22.3 0.2 0.00021 21.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SYCE1 PF15233.6 GAK63181.1 - 0.14 12.2 7.0 0.43 10.6 3.2 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF1840 PF08895.11 GAK63181.1 - 7 7.0 8.9 27 5.2 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Nup96 PF12110.8 GAK63182.1 - 5.2e-96 321.2 0.1 7.4e-96 320.7 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 GAK63182.1 - 2.2e-54 183.6 0.0 3.6e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 GAK63182.1 - 4.6e-22 78.7 381.2 2.4e-06 28.3 34.0 12.4 3 2 8 12 12 12 8 Nucleoporin FG repeat region CK2S PF15011.6 GAK63184.1 - 0.0033 17.3 0.8 0.0089 15.9 0.5 1.9 1 1 0 1 1 1 1 Casein Kinase 2 substrate Rep_fac-A_C PF08646.10 GAK63185.1 - 2.8e-58 195.8 4.1 1.1e-56 190.6 0.4 2.2 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GAK63185.1 - 5.6e-36 122.4 0.0 4.3e-35 119.6 0.0 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 GAK63185.1 - 1.3e-26 92.6 0.7 3.1e-26 91.3 0.7 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GAK63185.1 - 3.8e-12 46.0 0.1 5.6e-10 39.1 0.0 3.3 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 GAK63185.1 - 0.00085 19.1 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 GAK63185.1 - 0.012 15.9 0.2 0.033 14.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF223 DUF5521 PF17659.1 GAK63185.1 - 0.11 10.3 0.4 0.23 9.3 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5521) DUF4539 PF15072.6 GAK63185.1 - 0.15 12.1 0.0 0.51 10.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Dickkopf_N PF04706.12 GAK63187.1 - 1.3e-06 28.8 72.3 0.002 18.6 15.7 5.4 4 1 1 5 5 5 5 Dickkopf N-terminal cysteine-rich region EB PF01683.18 GAK63187.1 - 0.0014 18.9 76.8 0.028 14.7 11.2 6.8 1 1 6 7 7 7 6 EB module UPF0506 PF11703.8 GAK63187.1 - 0.018 15.4 65.4 0.068 13.6 12.4 4.8 4 2 0 4 4 4 0 UPF0506 Med3 PF11593.8 GAK63187.1 - 0.84 8.8 4.3 1.6 7.9 4.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mannosyl_trans3 PF11051.8 GAK63188.1 - 3.4e-29 102.1 0.0 5.2e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 GAK63189.1 - 1.7e-39 135.8 0.0 3.3e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Cyclin_C_2 PF16899.5 GAK63190.1 - 2.1e-15 57.0 0.2 1.7e-13 50.8 0.2 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 GAK63190.1 - 1.4e-06 28.0 0.1 2.5e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAK63190.1 - 0.0095 16.0 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIIB repeat RabGAP-TBC PF00566.18 GAK63192.1 - 2e-48 164.9 0.0 2.7e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 GAK63192.1 - 0.0079 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Glyco_transf_90 PF05686.12 GAK63193.1 - 4.2e-17 62.2 0.0 3.1e-14 52.7 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 90 Abhydrolase_3 PF07859.13 GAK63194.1 - 1.5e-29 103.4 0.1 2.1e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAK63194.1 - 0.00083 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 GAK63194.1 - 0.0016 17.9 0.0 0.009 15.5 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 GAK63194.1 - 0.0021 17.6 0.1 0.16 11.5 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 GAK63194.1 - 0.0049 17.0 0.0 0.0078 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.11 GAK63194.1 - 0.075 12.9 0.0 0.52 10.2 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 GAK63194.1 - 0.09 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 GAK63194.1 - 0.13 11.9 0.0 0.43 10.2 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Ku PF02735.16 GAK63195.1 - 2.3e-45 154.8 0.0 3.9e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAK63195.1 - 1.3e-16 61.1 0.0 5.9e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 GAK63195.1 - 2.3e-14 53.8 0.1 6.8e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 GAK63195.1 - 2.5e-07 30.3 0.0 5.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 GAK63195.1 - 0.0067 17.1 0.0 0.11 13.1 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VHS PF00790.19 GAK63195.1 - 0.1 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 VHS domain adh_short_C2 PF13561.6 GAK63196.1 - 1.8e-48 165.1 0.4 2.3e-48 164.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK63196.1 - 5e-35 120.7 0.0 6.5e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK63196.1 - 8.8e-09 35.5 0.0 1.3e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAK63196.1 - 0.0075 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein His_biosynth PF00977.21 GAK63196.1 - 0.02 14.3 0.0 0.052 13.0 0.0 1.7 1 1 0 1 1 1 0 Histidine biosynthesis protein Cbl_N3 PF02762.14 GAK63196.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Ribosomal_L39 PF00832.20 GAK63197.1 - 5.5e-17 61.1 10.0 1.1e-13 50.6 4.6 2.4 2 0 0 2 2 2 2 Ribosomal L39 protein Acetyltransf_7 PF13508.7 GAK63198.1 - 1.6e-05 25.2 0.1 0.0042 17.5 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK63198.1 - 1.8e-05 24.9 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAK63198.1 - 8.5e-05 22.5 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK63198.1 - 0.022 14.7 0.1 4.6 7.3 0.1 3.0 3 0 0 3 3 3 0 FR47-like protein zf-C2H2 PF00096.26 GAK63199.1 - 1.6e-11 44.0 16.5 0.00083 19.7 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK63199.1 - 3.7e-08 33.5 10.8 0.0016 18.8 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAK63199.1 - 4.3e-08 33.0 7.0 0.0027 17.6 1.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAK63199.1 - 1.2e-07 32.0 13.6 0.018 15.8 0.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger Spt20 PF12090.8 GAK63199.1 - 2 8.0 24.3 5.7 6.5 24.3 1.7 1 0 0 1 1 1 0 Spt20 family NAP PF00956.18 GAK63200.1 - 1.8e-97 325.8 4.2 2.8e-97 325.1 4.2 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Peptidase_C54 PF03416.19 GAK63201.1 - 1.5e-102 342.7 0.0 2.4e-102 342.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 IMS PF00817.20 GAK63202.1 - 1.7e-45 154.7 0.1 3.1e-45 153.8 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 GAK63202.1 - 1.4e-12 48.3 2.5 3.3e-12 47.1 2.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAK63202.1 - 3.5e-06 27.0 0.0 9.6e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif ParB PF08775.10 GAK63202.1 - 0.89 10.0 3.5 29 5.2 0.0 3.1 3 0 0 3 3 3 0 ParB family F1F0-ATPsyn_F PF10791.9 GAK63203.1 - 1.5e-29 102.3 0.0 1.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Ribosomal_S5 PF00333.20 GAK63204.1 - 3.4e-28 97.4 1.6 6.6e-28 96.5 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAK63204.1 - 6.3e-23 80.0 0.1 1e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain MUG113 PF13455.6 GAK63205.1 - 3.6e-15 56.4 0.0 8e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 GAK63205.1 - 7.1e-13 49.0 0.0 2.4e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 T5orf172 domain Ribosomal_S2 PF00318.20 GAK63206.1 - 3.8e-27 94.9 0.0 1.7e-12 47.0 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 GAK63206.1 - 1.7e-08 35.7 16.0 3.3e-08 34.8 16.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Zn_clus PF00172.18 GAK63207.1 - 3.5e-08 33.4 11.1 6.8e-08 32.5 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK63207.1 - 0.025 13.6 0.8 0.3 10.1 0.2 2.8 2 1 0 2 2 2 0 Fungal specific transcription factor domain IL11 PF07400.11 GAK63207.1 - 0.38 10.4 3.4 1.3 8.6 0.6 2.4 2 0 0 2 2 2 0 Interleukin 11 CDC45 PF02724.14 GAK63207.1 - 7.3 4.7 6.5 12 4.1 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein MPC PF03650.13 GAK63208.1 - 2e-36 124.4 0.1 2.4e-36 124.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF3684 PF12449.8 GAK63209.1 - 0 1237.3 0.0 0 1237.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Na_Ca_ex PF01699.24 GAK63210.1 - 9.4e-35 119.8 46.5 7.2e-18 65.0 20.7 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Glyco_transf_22 PF03901.17 GAK63210.1 - 0.0081 15.4 0.3 0.0081 15.4 0.3 3.5 2 1 1 3 3 3 2 Alg9-like mannosyltransferase family DUF3784 PF12650.7 GAK63210.1 - 0.3 11.3 0.0 0.3 11.3 0.0 4.6 4 1 1 6 6 6 0 Domain of unknown function (DUF3784) AMP-binding PF00501.28 GAK63211.1 - 1.8e-45 155.3 0.0 2.6e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAK63211.1 - 1.8e-09 37.4 0.9 1.8e-09 37.4 0.9 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAK63211.1 - 4.8e-05 24.2 0.1 0.00011 23.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PcfJ PF14284.6 GAK63211.1 - 0.15 11.9 0.0 0.67 9.8 0.0 1.9 2 0 0 2 2 2 0 PcfJ-like protein PEPCK_ATP PF01293.20 GAK63212.1 - 9.2e-222 736.7 0.0 1.1e-221 736.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 GAK63212.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ost5 PF05251.12 GAK63213.1 - 1.2e-15 57.5 11.3 2.1e-15 56.7 8.2 2.3 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit 5 CDC73_C PF05179.14 GAK63214.1 - 3.9e-54 182.6 0.1 6.8e-54 181.8 0.1 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 GAK63214.1 - 8.4e-05 22.0 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal INTAP PF16617.5 GAK63214.1 - 1.1 9.6 9.3 0.81 10.0 1.8 3.1 2 1 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Methyltr_RsmB-F PF01189.17 GAK63215.1 - 3.3e-36 124.8 0.0 6.1e-33 114.1 0.0 2.7 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Pribosyltran PF00156.27 GAK63215.1 - 3.1e-14 52.8 0.2 6.5e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FtsJ PF01728.19 GAK63215.1 - 0.057 13.5 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase tRNA-synt_1c PF00749.21 GAK63216.1 - 2e-107 358.7 0.0 2.9e-107 358.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 GAK63216.1 - 5.3e-42 143.6 0.0 8.7e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 GAK63216.1 - 8.5e-35 120.2 0.0 4e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 GAK63216.1 - 1.9e-06 28.7 1.0 1.9e-06 28.7 1.0 3.0 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 G-alpha PF00503.20 GAK63217.1 - 3.9e-121 404.5 1.0 4.5e-121 404.3 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAK63217.1 - 2.3e-17 63.0 0.8 5.9e-12 45.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 GAK63217.1 - 5.6e-05 22.9 0.1 0.00022 21.0 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 GAK63217.1 - 0.00018 21.0 6.5 0.00067 19.1 0.6 2.6 2 2 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GAK63217.1 - 0.00029 21.1 0.3 0.85 9.8 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAK63217.1 - 0.0083 15.9 0.3 0.09 12.5 0.3 2.4 1 1 1 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAK63217.1 - 0.011 15.8 0.0 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 GAK63217.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 GAK63217.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 GAK63217.1 - 0.16 11.5 0.1 2.6 7.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Pyridoxal_deC PF00282.19 GAK63219.1 - 1.1e-20 73.7 0.0 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAK63219.1 - 9.5e-07 28.1 0.0 2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAK63219.1 - 0.013 14.8 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAK63219.1 - 0.035 12.6 0.0 0.065 11.8 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme tRNA-synt_2 PF00152.20 GAK63220.1 - 9.4e-75 251.6 0.0 1.3e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Aldo_ket_red PF00248.21 GAK63220.1 - 1.4e-36 126.2 0.0 2.1e-34 119.1 0.0 2.6 1 1 0 1 1 1 1 Aldo/keto reductase family tRNA_anti-codon PF01336.25 GAK63220.1 - 1.8e-11 43.9 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAK63220.1 - 1.3e-07 31.3 0.0 0.00023 20.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DLEU7 PF15760.5 GAK63220.1 - 0.14 11.6 1.5 0.24 10.9 1.5 1.3 1 0 0 1 1 1 0 Leukemia-associated protein 7 Sugar_tr PF00083.24 GAK63221.1 - 8.9e-38 130.3 21.2 4.3e-36 124.8 21.2 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK63221.1 - 3.4e-30 105.2 30.8 3.4e-30 105.2 30.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Hamartin PF04388.12 GAK63223.1 - 3.3e-11 42.6 37.3 4.6e-11 42.2 23.4 5.0 2 1 0 2 2 2 1 Hamartin protein HOOK PF05622.12 GAK63223.1 - 0.0032 15.7 30.8 0.006 14.8 30.8 1.3 1 0 0 1 1 1 1 HOOK protein bZIP_1 PF00170.21 GAK63223.1 - 0.44 10.7 19.6 0.24 11.5 1.5 3.9 4 0 0 4 4 4 0 bZIP transcription factor SNCAIP_SNCA_bd PF16700.5 GAK63223.1 - 0.92 9.3 3.3 25 4.7 0.2 2.9 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Sulfatase_C PF14707.6 GAK63223.1 - 1.6 9.5 6.3 37 5.1 0.1 3.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase BLOC1_2 PF10046.9 GAK63223.1 - 2.9 8.3 19.1 0.76 10.1 2.6 3.7 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.18 GAK63223.1 - 4.6 7.6 10.9 8.5 6.8 0.5 4.1 3 0 0 3 3 3 0 TSC-22/dip/bun family zf-4CXXC_R1 PF10497.9 GAK63224.1 - 9.9e-07 28.9 12.9 5.6e-06 26.5 12.9 2.1 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 MAGP PF05507.11 GAK63224.1 - 0.084 13.3 0.2 0.26 11.7 0.2 1.8 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) POT1PC PF16686.5 GAK63225.1 - 9.7e-19 67.8 0.0 3.8e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 GAK63225.1 - 2.4e-11 43.6 0.0 4.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DZR PF12773.7 GAK63225.1 - 0.0063 16.5 1.2 0.013 15.5 1.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 GAK63225.1 - 0.032 15.0 0.1 0.059 14.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon family UPF0547 PF10571.9 GAK63225.1 - 0.26 11.4 1.9 0.93 9.6 1.9 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 EF_TS PF00889.19 GAK63226.1 - 2.2e-13 50.3 0.0 1.4e-12 47.6 0.0 2.2 3 0 0 3 3 3 1 Elongation factor TS LRR_8 PF13855.6 GAK63227.1 - 4.1e-14 52.1 9.7 6.1e-11 41.9 7.7 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAK63227.1 - 3.9e-10 39.8 17.4 2.7e-05 24.4 2.9 4.7 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAK63227.1 - 0.017 15.6 9.8 2.8 8.8 0.3 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 GAK63227.1 - 1.7 8.1 4.8 0.55 9.7 0.4 2.1 2 1 1 3 3 3 0 Leucine-rich repeat ABC_membrane PF00664.23 GAK63228.1 - 2.8e-93 312.5 22.8 3.8e-49 167.8 6.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK63228.1 - 3.6e-61 205.7 0.0 1.2e-31 110.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAK63228.1 - 2.8e-13 49.8 0.1 0.00018 21.0 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 GAK63228.1 - 7.9e-07 28.5 0.0 0.029 13.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 GAK63228.1 - 1.6e-06 28.5 1.2 1.2 9.5 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.6 GAK63228.1 - 1.4e-05 24.8 0.3 0.57 9.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.9 GAK63228.1 - 2e-05 23.6 0.1 0.0073 15.1 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 GAK63228.1 - 8e-05 22.3 0.2 0.48 10.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 GAK63228.1 - 9.5e-05 22.2 1.9 0.22 11.2 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.6 GAK63228.1 - 0.00032 20.6 0.0 2.4 7.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 GAK63228.1 - 0.0037 17.4 2.6 0.66 10.1 0.0 3.6 4 0 0 4 4 2 1 AAA domain G-alpha PF00503.20 GAK63228.1 - 0.0038 16.4 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 GAK63228.1 - 0.0039 17.6 9.1 0.092 13.1 0.5 3.8 3 2 0 3 3 3 2 AAA ATPase domain APS_kinase PF01583.20 GAK63228.1 - 0.0052 16.7 0.1 0.095 12.6 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase SRP54 PF00448.22 GAK63228.1 - 0.0067 16.1 0.0 0.84 9.2 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 GAK63228.1 - 0.01 15.2 0.1 0.062 12.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 GAK63228.1 - 0.01 15.7 0.0 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase DEAD PF00270.29 GAK63228.1 - 0.016 14.9 0.9 0.7 9.6 0.1 3.1 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_18 PF13238.6 GAK63228.1 - 0.03 14.9 0.0 0.79 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SUIM_assoc PF16619.5 GAK63228.1 - 0.031 14.4 6.6 0.21 11.7 6.6 2.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AAA_24 PF13479.6 GAK63228.1 - 0.056 13.2 0.3 9.2 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 GAK63228.1 - 0.056 13.1 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 GAK63228.1 - 0.063 13.7 0.1 7.3 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAK63228.1 - 0.09 12.9 3.0 1.9 8.5 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_5 PF07728.14 GAK63228.1 - 0.11 12.5 0.3 2.4 8.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 GAK63228.1 - 0.17 12.2 12.7 1.7 8.9 0.7 5.1 3 3 0 3 3 3 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 GAK63228.1 - 0.25 11.1 1.2 17 5.1 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Mcm10 PF09332.11 GAK63228.1 - 0.33 10.3 3.3 0.83 9.0 3.3 1.6 1 0 0 1 1 1 0 Mcm10 replication factor DLIC PF05783.11 GAK63228.1 - 3.8 6.2 6.1 17 4.1 0.0 2.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PALP PF00291.25 GAK63229.1 - 1.2e-80 271.0 0.3 1.6e-80 270.6 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 GAK63229.1 - 2.4e-41 139.4 0.0 8.2e-23 80.0 0.0 3.7 4 0 0 4 4 4 3 C-terminal regulatory domain of Threonine dehydratase MMR_HSR1 PF01926.23 GAK63230.1 - 3.5e-18 65.7 0.0 1.2e-13 51.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK63230.1 - 1.2e-09 37.8 0.0 5.4e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAK63230.1 - 2.9e-06 27.3 0.7 0.083 12.8 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 GAK63230.1 - 6.2e-05 22.6 0.0 0.002 17.7 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAK63230.1 - 0.00036 20.6 0.4 0.043 13.9 0.2 2.9 2 1 1 3 3 3 1 Dynamin family MeaB PF03308.16 GAK63230.1 - 0.041 12.9 0.2 2.2 7.2 0.1 3.3 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB tRNA-synt_1b PF00579.25 GAK63231.1 - 7.7e-69 232.2 0.0 1.1e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 GAK63231.1 - 2.3e-05 24.2 0.4 0.00097 18.9 0.0 2.4 1 1 1 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 GAK63231.1 - 0.0035 17.0 0.1 0.0085 15.8 0.1 1.6 1 0 0 1 1 1 1 S4 domain MgtE_N PF03448.17 GAK63231.1 - 0.04 14.5 0.5 0.068 13.8 0.5 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain WD40 PF00400.32 GAK63232.1 - 3.1e-61 201.9 17.6 0.00012 22.7 0.0 12.7 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.11 GAK63232.1 - 6.5e-47 159.0 0.7 1.3e-46 158.0 0.7 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 GAK63232.1 - 9.1e-12 45.1 5.7 0.51 10.7 0.0 8.1 5 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAK63232.1 - 0.00024 20.0 1.6 1.3 7.6 0.0 5.5 3 3 2 5 5 5 1 Nup133 N terminal like WD40_like PF17005.5 GAK63232.1 - 0.00027 20.3 0.0 0.42 9.9 0.0 3.3 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 GAK63232.1 - 0.00046 19.0 9.9 4 6.0 0.0 6.7 4 3 1 6 6 6 2 Nucleoporin Nup120/160 Hira PF07569.11 GAK63232.1 - 0.0022 17.7 2.3 15 5.2 0.0 5.2 5 1 1 6 6 6 1 TUP1-like enhancer of split Peptidase_M14 PF00246.24 GAK63233.1 - 7.3e-63 213.1 0.0 1.1e-62 212.4 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Trypan_PARP PF05887.11 GAK63233.1 - 0.001 19.0 4.2 0.0022 18.0 4.2 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF5593 PF18007.1 GAK63233.1 - 0.12 13.1 0.1 0.93 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5593) tRNA-synt_1 PF00133.22 GAK63234.1 - 9.8e-36 123.2 0.0 2.1e-27 95.7 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAK63234.1 - 1.9e-16 59.8 0.0 1.3e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAK63234.1 - 1.1e-12 48.2 0.0 2.6e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAK63234.1 - 1.7e-06 27.6 0.0 4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Med12 PF09497.10 GAK63235.1 - 6.1e-33 112.9 0.1 3.7e-32 110.4 0.0 2.4 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 GAK63235.1 - 7e-06 25.2 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain ARPC4 PF05856.12 GAK63236.1 - 6.8e-72 240.5 6.9 7.5e-72 240.4 6.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Mito_carr PF00153.27 GAK63237.1 - 3.5e-44 148.7 8.7 1e-17 63.8 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-sulfurylase PF01747.17 GAK63239.1 - 3.9e-88 294.4 0.1 5.5e-88 294.0 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 GAK63239.1 - 4.4e-55 185.9 0.0 6.5e-55 185.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 GAK63239.1 - 3.7e-53 179.4 0.0 6.1e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 GAK63239.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NDUF_B12 PF08122.12 GAK63240.1 - 1.1e-18 66.9 0.3 1.4e-18 66.7 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Topoisom_I_N PF02919.15 GAK63241.1 - 7.7e-81 270.7 0.2 7.7e-81 270.7 0.2 3.8 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 GAK63241.1 - 3.8e-79 265.2 5.5 3.8e-79 265.2 5.5 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 GAK63241.1 - 1.8e-15 56.6 0.9 3.3e-11 43.0 0.1 3.1 3 0 0 3 3 3 2 C-terminal topoisomerase domain RPEL PF02755.15 GAK63242.1 - 5.4e-27 92.7 42.3 4.5e-08 32.5 3.1 5.0 6 0 0 6 6 6 4 RPEL repeat Antimicrobial18 PF08130.11 GAK63242.1 - 0.0023 18.0 0.8 2.7 8.2 0.0 3.2 3 0 0 3 3 3 1 Type A lantibiotic family Hanta_nucleocap PF00846.18 GAK63242.1 - 0.074 11.5 4.5 4.4 5.6 0.2 2.8 1 1 2 3 3 3 0 Hantavirus nucleocapsid protein DnaI_N PF07319.11 GAK63242.1 - 0.12 13.1 0.3 23 5.7 0.1 2.4 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus Post_transc_reg PF13797.6 GAK63242.1 - 0.17 11.7 0.2 15 5.6 0.0 2.8 3 0 0 3 3 3 0 Post-transcriptional regulator TPR_1 PF00515.28 GAK63243.1 - 6.3e-21 73.3 2.7 0.00012 21.7 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAK63243.1 - 2e-15 56.2 0.8 0.00098 18.8 0.0 4.5 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.17 GAK63243.1 - 1.1e-14 53.3 10.7 0.00043 20.2 0.2 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAK63243.1 - 5.4e-14 51.2 3.1 0.0038 17.3 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAK63243.1 - 2.3e-11 43.5 5.3 0.027 15.2 0.0 6.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAK63243.1 - 1.5e-09 37.6 4.0 0.0045 17.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAK63243.1 - 6.9e-09 35.9 6.4 4.4e-05 23.7 0.0 4.7 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAK63243.1 - 2.4e-08 33.5 6.7 0.04 13.9 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAK63243.1 - 3.1e-08 34.1 15.0 0.0018 18.9 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAK63243.1 - 3e-06 27.6 7.0 0.082 13.4 0.0 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAK63243.1 - 3.7e-05 23.8 9.5 0.012 15.7 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK63243.1 - 0.0019 18.4 4.5 0.026 14.7 0.8 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 GAK63243.1 - 0.0054 16.7 0.0 2.2 8.4 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAK63243.1 - 0.021 14.7 0.8 0.021 14.7 0.8 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3507 PF12015.8 GAK63243.1 - 0.098 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) SRC-1 PF08832.10 GAK63243.1 - 0.11 13.6 0.4 0.78 10.8 0.0 2.7 2 0 0 2 2 1 0 Steroid receptor coactivator TPR_20 PF14561.6 GAK63243.1 - 0.14 12.5 13.6 0.59 10.5 2.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 GAK63243.1 - 0.72 10.0 4.5 20 5.3 0.0 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 GAK63243.1 - 2.2 8.4 5.0 3.1 7.9 0.0 3.6 4 1 0 4 4 4 0 MAS20 protein import receptor Sugar_tr PF00083.24 GAK63244.1 - 2.4e-114 382.7 24.1 3.1e-114 382.3 24.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Asp PF00026.23 GAK63244.1 - 1.7e-27 96.7 0.0 2.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease MFS_1 PF07690.16 GAK63244.1 - 6.5e-22 77.9 40.2 9.4e-16 57.7 9.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TAXi_N PF14543.6 GAK63244.1 - 1.2e-07 32.2 0.3 1.3e-05 25.5 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Lactamase_B PF00753.27 GAK63244.1 - 3.1e-07 30.6 0.1 7e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAK63244.1 - 0.0075 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CysA_C_terminal PF17850.1 GAK63244.1 - 0.12 12.9 0.1 1.3 9.6 0.1 2.7 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Asp_protease_2 PF13650.6 GAK63244.1 - 0.13 12.9 0.0 0.58 10.8 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease ABC_membrane PF00664.23 GAK63245.1 - 1.9e-80 270.4 12.7 1.3e-43 149.7 1.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK63245.1 - 1.8e-60 203.4 0.0 4.8e-30 104.9 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAK63245.1 - 2.7e-13 49.9 0.0 7.8e-06 25.5 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAK63245.1 - 2.4e-08 34.1 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 GAK63245.1 - 1.3e-07 30.8 0.0 0.024 13.5 0.0 3.2 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 GAK63245.1 - 1.7e-07 30.9 0.3 0.0053 16.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAK63245.1 - 1.6e-06 28.5 0.0 0.016 15.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAK63245.1 - 2.5e-06 27.5 0.0 0.078 12.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 GAK63245.1 - 2.5e-06 27.2 0.1 0.25 10.9 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 GAK63245.1 - 7.2e-06 26.5 0.9 0.061 13.7 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 GAK63245.1 - 2.1e-05 25.1 0.0 0.14 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 GAK63245.1 - 2.5e-05 24.9 0.1 0.011 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAK63245.1 - 5.3e-05 23.2 0.0 0.23 11.2 0.0 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 GAK63245.1 - 0.00025 20.6 0.0 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 GAK63245.1 - 0.0015 18.7 0.0 0.47 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 GAK63245.1 - 0.0071 16.6 1.8 3.6 7.9 0.3 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 GAK63245.1 - 0.024 14.7 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 GAK63245.1 - 0.03 14.1 0.0 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 GAK63245.1 - 0.041 14.0 0.2 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DLIC PF05783.11 GAK63245.1 - 0.046 12.6 0.0 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Zeta_toxin PF06414.12 GAK63245.1 - 0.057 12.7 0.0 8.6 5.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF3987 PF13148.6 GAK63245.1 - 0.072 12.1 0.4 0.24 10.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RNA_helicase PF00910.22 GAK63245.1 - 0.076 13.4 0.2 6.7 7.2 0.0 3.0 2 1 1 3 3 3 0 RNA helicase AAA_5 PF07728.14 GAK63245.1 - 0.094 12.7 0.0 2.8 7.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 GAK63245.1 - 0.095 11.8 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 GAK63245.1 - 0.13 12.5 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAK63245.1 - 0.16 12.4 0.0 18 5.7 0.0 3.3 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) eIF-5_eIF-2B PF01873.17 GAK63246.1 - 3.1e-42 143.2 0.2 4.7e-42 142.6 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 GAK63246.1 - 0.011 15.3 0.2 0.02 14.4 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf_C2H2_13 PF18508.1 GAK63246.1 - 0.69 9.5 3.7 2.4 7.8 0.3 2.2 1 1 1 2 2 2 0 Zinc finger domain ATP-synt PF00231.19 GAK63247.1 - 4.9e-69 233.2 7.9 1e-65 222.3 4.1 2.0 2 0 0 2 2 2 2 ATP synthase LysM PF01476.20 GAK63249.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 LysM domain SNF2_N PF00176.23 GAK63250.1 - 7.8e-61 205.7 0.0 1.2e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 GAK63250.1 - 6.9e-28 96.9 0.4 2.5e-27 95.2 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 GAK63250.1 - 2.1e-23 82.0 2.1 8.2e-15 54.5 0.1 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GAK63250.1 - 4.6e-19 68.8 0.0 1.1e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK63250.1 - 7.3e-10 39.1 0.0 4.1e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 GAK63250.1 - 4.4e-07 30.2 0.1 4.4e-07 30.2 0.1 4.2 5 0 0 5 5 5 1 Chromodomain helicase DNA-binding domain 1 DEAD PF00270.29 GAK63250.1 - 3.3e-05 23.7 0.0 9.5e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase CDH1_2_SANT_HL1 PF18375.1 GAK63250.1 - 0.0028 18.3 0.2 0.016 15.9 0.2 2.3 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 CHDCT2 PF08074.11 GAK63250.1 - 0.11 12.6 3.1 0.14 12.3 0.0 2.8 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain zf-C3HC4_2 PF13923.6 GAK63251.1 - 6.9e-09 35.4 10.4 4.1e-08 32.9 7.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK63251.1 - 8.4e-09 35.2 9.8 8.4e-09 35.2 9.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAK63251.1 - 3.2e-07 30.1 3.4 3.2e-07 30.1 3.4 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 GAK63251.1 - 4.8e-07 29.7 12.1 1.4e-06 28.2 7.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAK63251.1 - 8.7e-06 26.0 14.5 2.8e-05 24.4 8.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAK63251.1 - 1.5e-05 25.0 12.8 1.7e-05 24.9 9.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GAK63251.1 - 1.5e-05 24.8 13.6 4.2e-05 23.4 9.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 GAK63251.1 - 2.7e-05 23.9 5.4 0.00044 20.0 2.7 2.6 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 GAK63251.1 - 6.8e-05 22.5 1.2 0.00016 21.4 0.0 2.3 3 0 0 3 3 2 1 SAP domain zf-C3HC4_3 PF13920.6 GAK63251.1 - 0.0002 21.1 9.7 0.00053 19.8 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Actin_micro PF17003.5 GAK63251.1 - 0.00043 19.6 0.0 0.00069 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative actin-like family zf-ANAPC11 PF12861.7 GAK63251.1 - 0.00065 19.7 4.6 0.0016 18.5 1.7 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.6 GAK63251.1 - 0.0021 17.9 0.1 0.0021 17.9 0.1 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Prok-RING_4 PF14447.6 GAK63251.1 - 0.012 15.5 12.6 0.88 9.5 9.4 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAK63251.1 - 0.016 15.3 4.2 0.041 14.0 4.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 GAK63251.1 - 0.03 14.6 9.2 0.064 13.6 4.9 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain Cys_rich_KTR PF14205.6 GAK63251.1 - 0.045 13.6 0.9 1.8 8.4 0.4 2.6 2 0 0 2 2 2 0 Cysteine-rich KTR PRR20 PF15708.5 GAK63251.1 - 0.086 12.7 4.3 0.99 9.3 0.4 2.6 2 0 0 2 2 2 0 Proline-rich protein family 20 zf-C2H2_4 PF13894.6 GAK63251.1 - 0.29 12.1 0.1 0.29 12.1 0.1 4.1 3 1 1 4 4 4 0 C2H2-type zinc finger zf-RING_4 PF14570.6 GAK63251.1 - 0.35 10.7 10.4 0.31 10.9 6.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 GAK63251.1 - 0.38 10.7 5.2 4 7.5 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-Di19 PF05605.12 GAK63251.1 - 0.59 10.5 6.6 0.29 11.5 0.4 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TipAS PF07739.13 GAK63251.1 - 1.2 9.7 0.0 1.2 9.7 0.0 2.6 2 1 1 3 3 2 0 TipAS antibiotic-recognition domain zf-MIZ PF02891.20 GAK63251.1 - 7.9 6.3 8.9 51 3.7 6.2 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger NOB1_Zn_bind PF08772.11 GAK63251.1 - 8.8 6.6 10.6 7.8 6.7 4.9 2.6 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Tannase PF07519.11 GAK63254.1 - 2e-114 383.1 1.0 2.6e-114 382.7 1.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 GAK63254.1 - 0.051 13.0 1.5 3.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_11 PF00457.17 GAK63256.1 - 4.1e-59 199.2 19.3 4.9e-59 198.9 19.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 HopJ PF08888.11 GAK63256.1 - 0.02 15.1 0.9 0.045 14.0 0.6 1.8 1 1 1 2 2 2 0 HopJ type III effector protein PI-PLC-X PF00388.19 GAK63257.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain MFS_1 PF07690.16 GAK63258.1 - 3.2e-20 72.4 23.2 3.2e-20 72.4 23.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK63258.1 - 1.8e-05 23.8 1.5 1.8e-05 23.8 1.5 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF4191 PF13829.6 GAK63258.1 - 0.0079 15.6 4.7 0.027 13.8 1.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4191) DUF5090 PF17009.5 GAK63258.1 - 0.97 9.4 6.7 0.18 11.7 1.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5090) Zn_clus PF00172.18 GAK63259.1 - 1.4e-08 34.8 8.8 2.6e-08 33.9 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK63259.1 - 0.0061 15.6 0.1 0.43 9.6 0.0 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain Peptidase_S15 PF02129.18 GAK63260.1 - 2.2e-40 139.0 4.1 2.9e-34 118.9 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAK63260.1 - 1.4e-32 113.5 0.0 1.9e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF1479 PF07350.12 GAK63261.1 - 1.5e-06 27.2 0.0 0.14 10.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.13 GAK63261.1 - 2.8e-05 24.5 0.0 0.00011 22.5 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAK63261.1 - 0.017 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 GAK63261.1 - 0.13 13.2 0.0 0.27 12.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 GAK63262.1 - 2.4e-24 86.2 0.0 5.3e-24 85.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 GAK63262.1 - 4.9e-06 25.8 0.0 8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 GAK63262.1 - 0.00021 20.7 0.4 0.0022 17.3 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK63262.1 - 0.0011 18.3 0.0 0.051 12.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK63262.1 - 0.0087 16.3 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAK63262.1 - 0.021 14.8 0.3 0.6 10.1 0.0 3.0 2 2 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAK63262.1 - 0.19 10.8 0.6 0.3 10.1 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Dynactin_p62 PF05502.13 GAK63263.1 - 6e-62 210.0 17.2 3.4e-60 204.2 17.2 2.9 1 1 0 1 1 1 1 Dynactin p62 family Nop14 PF04147.12 GAK63263.1 - 2.6 6.2 5.4 3.8 5.6 5.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAK63263.1 - 8.3 4.6 13.5 0.19 10.0 5.2 2.0 2 0 0 2 2 2 0 CDC45-like protein polyprenyl_synt PF00348.17 GAK63264.1 - 4.9e-93 310.9 0.0 6.1e-93 310.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YtzH PF14165.6 GAK63264.1 - 0.035 14.5 0.1 0.13 12.6 0.0 2.0 1 1 1 2 2 2 0 YtzH-like protein MCM PF00493.23 GAK63265.1 - 1.1e-100 335.3 0.0 1.8e-100 334.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAK63265.1 - 1e-37 128.8 0.0 1.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 GAK63265.1 - 1.7e-31 109.6 25.4 1.7e-31 109.6 25.4 4.0 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 GAK63265.1 - 8.7e-26 90.2 0.8 4.6e-25 87.9 0.6 2.4 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 GAK63265.1 - 3.4e-13 50.1 0.0 8.7e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAK63265.1 - 1.5e-08 34.3 0.0 4.3e-07 29.5 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAK63265.1 - 1.9e-06 27.9 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAK63265.1 - 1.6e-05 24.8 0.3 0.00025 20.9 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAK63265.1 - 0.012 15.4 0.1 0.093 12.4 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 GAK63265.1 - 0.084 13.3 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 GAK63265.1 - 0.089 12.6 1.3 0.25 11.2 0.3 2.3 2 0 0 2 2 2 0 AAA lid domain DNA_gyraseB_C PF00986.21 GAK63265.1 - 0.15 12.2 1.0 46 4.3 0.0 3.3 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus Rsa3 PF14615.6 GAK63266.1 - 3.2e-14 52.2 0.0 6e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 PBP1_TM PF14812.6 GAK63266.1 - 1.1 9.7 9.2 4.5 7.7 5.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 GAK63267.1 - 2.3e-23 82.6 0.1 4e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAK63267.1 - 6.9e-09 35.7 8.5 0.00023 21.4 3.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK63267.1 - 0.0004 21.0 6.8 0.047 14.5 3.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 GAK63267.1 - 0.0017 18.3 1.9 0.0017 18.3 1.9 2.1 2 0 0 2 2 2 1 BED zinc finger zf-Di19 PF05605.12 GAK63267.1 - 0.021 15.1 0.6 0.048 14.0 0.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 GAK63267.1 - 0.052 13.9 2.9 2.5 8.5 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 GAK63267.1 - 0.095 13.2 0.2 0.21 12.1 0.2 1.6 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 GAK63267.1 - 0.31 10.8 2.3 0.69 9.7 2.3 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 GAK63267.1 - 0.46 11.0 7.0 2.3 8.8 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Epimerase PF01370.21 GAK63268.1 - 5.2e-16 58.8 0.0 6.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAK63268.1 - 4e-11 42.9 0.0 5.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAK63268.1 - 1.7e-06 27.2 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAK63268.1 - 4.5e-06 26.0 0.0 6.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAK63268.1 - 0.00058 19.1 0.0 0.13 11.5 0.0 2.8 1 1 1 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 GAK63268.1 - 0.002 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 GAK63268.1 - 0.07 12.3 0.0 0.38 9.8 0.0 2.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 GAK63269.1 - 2e-34 119.1 28.7 2.3e-34 118.9 27.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 GAK63270.1 - 1.6e-51 175.2 0.1 3.1e-31 108.7 0.1 3.4 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63270.1 - 1.4e-26 93.4 0.9 6.5e-22 78.1 0.0 3.4 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.6 GAK63270.1 - 5.3e-05 22.7 0.0 0.15 11.4 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 GAK63270.1 - 0.0018 17.2 0.0 0.0039 16.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAK63270.1 - 0.023 14.6 3.6 0.055 13.4 0.2 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.17 GAK63272.1 - 4.7e-75 252.9 20.9 5.5e-61 206.7 7.4 3.3 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase UbiA PF01040.18 GAK63273.1 - 2.8e-45 154.6 18.9 2.8e-45 154.6 18.9 2.7 2 1 0 2 2 2 1 UbiA prenyltransferase family MCU PF04678.13 GAK63273.1 - 6.4e-29 101.3 0.0 1.3e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Brr6_like_C_C PF10104.9 GAK63275.1 - 1.3e-41 141.4 0.6 1.7e-41 141.1 0.6 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.6 GAK63275.1 - 0.0025 18.2 2.2 0.0066 16.8 2.2 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Y_phosphatase2 PF03162.13 GAK63276.1 - 3.7e-25 88.4 0.0 3.4e-16 59.2 0.0 2.3 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAK63276.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RNA_pol_3_Rpc31 PF11705.8 GAK63276.1 - 0.86 9.8 29.4 2.4 8.3 29.4 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 GAK63276.1 - 9 5.8 29.3 0.62 9.6 23.6 1.9 2 0 0 2 2 2 0 PPP4R2 AIP3 PF03915.13 GAK63277.1 - 2.5e-139 464.9 1.5 2.5e-139 464.9 1.5 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 CHDCT2 PF08074.11 GAK63277.1 - 0.92 9.7 4.1 0.62 10.2 0.0 2.7 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DUF383 PF04063.14 GAK63278.1 - 1.3e-60 204.3 0.0 3.6e-60 202.9 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GAK63278.1 - 3.3e-16 58.9 0.6 7.7e-16 57.7 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.22 GAK63278.1 - 0.066 13.5 0.1 0.61 10.5 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat Zn_clus PF00172.18 GAK63279.1 - 2.1e-09 37.4 10.2 4.7e-09 36.2 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK63279.1 - 0.015 14.4 0.3 0.025 13.6 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain HMG_box PF00505.19 GAK63280.1 - 1.4e-09 38.2 4.4 1.7e-08 34.7 4.4 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box DNA_pol_B PF00136.21 GAK63281.1 - 1.6e-149 498.6 1.1 2.1e-149 498.2 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAK63281.1 - 4.1e-89 299.1 0.0 6.8e-89 298.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAK63281.1 - 7.3e-17 61.6 8.9 1.6e-16 60.5 8.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 GAK63281.1 - 0.0053 15.7 0.4 0.027 13.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral AMP-binding PF00501.28 GAK63282.1 - 2.2e-84 283.5 0.0 2.9e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK63282.1 - 1.2e-13 51.8 0.3 3.5e-13 50.3 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 GAK63282.1 - 0.00014 20.9 0.0 0.025 13.5 0.0 2.2 2 0 0 2 2 2 2 GH3 auxin-responsive promoter HK PF02110.15 GAK63282.1 - 0.036 13.4 0.2 0.078 12.4 0.0 1.6 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Methyltr_RsmB-F PF01189.17 GAK63283.1 - 2.5e-73 246.0 0.0 3.8e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GAK63283.1 - 9.9e-09 35.6 0.0 2.5e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 GAK63283.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 GAK63283.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAK63283.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 GAK63283.1 - 0.0087 16.2 0.0 0.024 14.8 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase YlbD_coat PF14071.6 GAK63283.1 - 0.025 14.8 1.9 0.025 14.8 1.9 2.8 2 1 0 2 2 2 0 Putative coat protein DUF3564 PF12087.8 GAK63283.1 - 0.069 13.1 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) DUF2431 PF10354.9 GAK63283.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF938 PF06080.12 GAK63283.1 - 0.11 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Hamartin PF04388.12 GAK63283.1 - 0.12 11.0 15.9 0.16 10.6 15.9 1.1 1 0 0 1 1 1 0 Hamartin protein Acyl-CoA_dh_1 PF00441.24 GAK63284.1 - 2e-31 109.2 0.3 3.1e-31 108.6 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAK63284.1 - 4e-17 62.2 0.5 7.6e-17 61.3 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 GAK63284.1 - 3.2e-16 59.2 0.0 7.9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 GAK63284.1 - 5.5e-13 49.6 0.0 8.4e-12 45.8 0.0 2.8 3 1 1 4 4 4 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAK63284.1 - 5.9e-08 33.1 0.9 8.2e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAK63284.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Nexin_C PF08628.12 GAK63285.1 - 1.2e-14 54.8 0.0 4e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PXA PF02194.15 GAK63285.1 - 5.3e-14 52.6 0.3 1.5e-13 51.2 0.2 1.8 2 0 0 2 2 2 1 PXA domain OrsD PF12013.8 GAK63285.1 - 0.077 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D EIF_2_alpha PF07541.12 GAK63286.1 - 9.1e-37 125.7 0.2 2e-36 124.6 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 GAK63286.1 - 7.7e-15 55.0 1.5 1.7e-14 53.9 0.5 2.1 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.9 GAK63286.1 - 0.019 15.6 1.1 0.77 10.4 0.2 3.1 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 NRDE-2 PF08424.10 GAK63287.1 - 5.9e-38 130.8 0.5 2.4e-37 128.8 0.1 2.2 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference Ank_2 PF12796.7 GAK63287.1 - 5.1e-05 23.8 0.0 0.00017 22.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK63287.1 - 0.00012 22.5 0.2 0.00056 20.4 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAK63287.1 - 0.0012 19.1 1.7 0.063 13.6 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAK63287.1 - 0.0026 18.1 0.4 2.4 9.0 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAK63287.1 - 0.035 14.5 5.0 2 9.0 0.0 3.9 5 0 0 5 5 5 0 Ankyrin repeat Stealth_CR2 PF11380.8 GAK63288.1 - 4.4e-10 39.7 1.7 1.1e-06 28.8 0.4 3.6 3 1 0 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 GAK63288.1 - 3.4e-09 36.5 0.2 8.1e-09 35.2 0.2 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 GAK63288.1 - 7.4e-06 25.6 0.1 1.9e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 GAK63288.1 - 0.0015 18.4 0.0 0.0073 16.2 0.0 2.1 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Keratin_assoc PF09775.9 GAK63289.1 - 2 8.0 7.1 1.6 8.4 1.9 2.6 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Carn_acyltransf PF00755.20 GAK63291.1 - 7.2e-173 576.4 0.0 8.3e-173 576.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Trehalase PF01204.18 GAK63292.1 - 1.9e-174 581.3 0.1 2.5e-174 580.9 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 GAK63292.1 - 2e-15 56.2 0.2 3.6e-15 55.4 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GST_N_2 PF13409.6 GAK63292.1 - 2.2e-15 56.7 0.1 9.4e-15 54.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK63292.1 - 3e-12 46.4 0.0 7.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAK63292.1 - 8.5e-06 25.9 0.0 3.6e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAK63292.1 - 0.00041 20.5 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RabGAP-TBC PF00566.18 GAK63293.1 - 3.4e-52 177.2 0.0 4.8e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CPSF73-100_C PF11718.8 GAK63294.1 - 1.9e-54 184.5 0.9 5.7e-54 182.9 0.9 1.8 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 GAK63294.1 - 5.8e-29 100.6 0.0 2.2e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 GAK63294.1 - 1.6e-21 77.3 0.6 4.4e-21 75.8 0.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 GAK63294.1 - 1.3e-19 70.4 0.0 3.2e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 GAK63294.1 - 1e-16 60.6 0.1 2.8e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 GAK63294.1 - 2.7e-08 33.9 0.4 9.3e-08 32.1 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GAK63294.1 - 1.6e-07 31.1 3.0 3.4e-07 30.0 1.3 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain MRP_L53 PF10780.9 GAK63295.1 - 9.1e-05 22.6 0.1 0.00016 21.8 0.1 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Tti2 PF10521.9 GAK63296.1 - 8.4e-20 71.4 0.0 7.9e-19 68.3 0.0 2.2 1 1 0 1 1 1 1 Tti2 family tRNA-synt_1d PF00750.19 GAK63297.1 - 1.1e-95 320.6 1.6 1.5e-95 320.1 1.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAK63297.1 - 7.6e-22 77.7 0.0 2.1e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain POT1 PF02765.17 GAK63297.1 - 0.013 15.4 0.0 0.075 12.9 0.0 2.0 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 UxaE PF16257.5 GAK63297.1 - 0.068 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 tagaturonate epimerase FlxA PF14282.6 GAK63298.1 - 0.0015 18.5 1.3 0.0015 18.5 1.3 3.5 4 0 0 4 4 4 1 FlxA-like protein Spc7 PF08317.11 GAK63298.1 - 0.049 12.5 22.3 0.038 12.9 12.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 GAK63298.1 - 0.28 11.0 17.5 0.02 14.7 9.0 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 GAK63298.1 - 2.3 8.3 24.7 0.37 10.9 2.1 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 GAK63298.1 - 2.8 8.7 17.0 5 7.8 2.0 3.4 2 1 1 3 3 3 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 GAK63298.1 - 4.7 7.3 33.9 5.2 7.1 19.4 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 GAK63298.1 - 7.4 6.9 9.5 11 6.4 3.7 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein FNIP_N PF14636.6 GAK63299.1 - 0.036 15.0 1.5 0.062 14.3 1.5 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus ArabFuran-catal PF09206.11 GAK63300.1 - 8.3e-148 491.8 14.2 9.4e-148 491.7 14.2 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic F-box-like PF12937.7 GAK63301.1 - 0.14 12.1 0.5 0.43 10.5 0.5 1.9 1 1 0 1 1 1 0 F-box-like GCP_N_terminal PF17681.1 GAK63302.1 - 2.2e-65 221.3 0.0 3.6e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAK63302.1 - 6.6e-38 130.9 6.1 1.1e-37 130.2 6.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DPBB_1 PF03330.18 GAK63302.1 - 0.16 12.3 0.0 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Lytic transglycolase GAS PF13851.6 GAK63302.1 - 7.5 5.9 8.6 0.46 9.8 2.6 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DEK_C PF08766.11 GAK63303.1 - 2.7e-13 49.6 0.1 5.2e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain Sugar_tr PF00083.24 GAK63304.1 - 1.8e-100 337.0 21.0 2e-100 336.8 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK63304.1 - 2.6e-20 72.7 27.7 4.6e-19 68.6 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_4 PF12799.7 GAK63306.1 - 2.8e-32 110.2 34.8 1.9e-09 37.6 3.1 6.6 2 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAK63306.1 - 3.4e-20 71.6 26.1 2.6e-08 33.5 2.9 5.5 4 1 2 6 6 6 5 Leucine rich repeat WD40 PF00400.32 GAK63306.1 - 3.5e-20 72.0 7.0 0.00097 19.9 0.0 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat LRR_9 PF14580.6 GAK63306.1 - 1e-14 54.4 12.5 2.4e-06 27.2 1.3 4.2 1 1 3 4 4 4 3 Leucine-rich repeat PQQ_2 PF13360.6 GAK63306.1 - 2.2e-07 30.7 3.6 3.6e-06 26.7 0.4 2.3 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 GAK63306.1 - 2.2e-05 24.7 0.0 3.8 7.9 0.0 4.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAK63306.1 - 0.00028 20.3 0.0 0.00094 18.6 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain PQQ PF01011.21 GAK63306.1 - 0.0063 16.4 2.5 2.4 8.2 0.0 4.5 4 0 0 4 4 4 1 PQQ enzyme repeat LRR_1 PF00560.33 GAK63306.1 - 0.014 15.8 21.4 9 7.3 0.3 8.3 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 GAK63306.1 - 0.057 13.5 21.4 0.92 9.7 0.3 6.9 6 1 1 7 7 6 0 Leucine Rich repeat zf-RING_10 PF16685.5 GAK63306.1 - 0.094 12.9 2.8 0.2 11.8 2.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 LysM PF01476.20 GAK63306.1 - 0.16 12.0 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 LysM domain PQQ_3 PF13570.6 GAK63306.1 - 0.94 10.1 12.3 0.42 11.2 0.1 4.5 5 0 0 5 5 4 0 PQQ-like domain zf-RING_5 PF14634.6 GAK63306.1 - 4.6 7.3 6.0 9.9 6.2 6.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FA_hydroxylase PF04116.13 GAK63307.1 - 1.8e-19 70.4 19.2 1.8e-19 70.4 19.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M16 PF00675.20 GAK63308.1 - 1.1e-21 77.4 2.4 2.3e-21 76.3 0.4 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAK63308.1 - 2.1e-11 44.2 0.0 7.5e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Sad1_UNC PF07738.13 GAK63309.1 - 2e-08 34.3 0.0 6.3e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF445 PF04286.12 GAK63309.1 - 0.0012 18.8 4.4 0.0017 18.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) ARGLU PF15346.6 GAK63309.1 - 0.07 13.0 5.5 0.47 10.3 1.4 2.5 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Trimer_CC PF08954.11 GAK63309.1 - 0.35 10.5 0.0 0.35 10.5 0.0 3.1 3 0 0 3 3 3 0 Trimerisation motif GvpL_GvpF PF06386.11 GAK63309.1 - 2.6 7.9 6.5 5.3 6.9 6.5 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Nup54 PF13874.6 GAK63309.1 - 3 8.0 6.4 10 6.2 6.4 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 ATP_bind_1 PF03029.17 GAK63310.1 - 1.8e-72 244.0 0.3 6.4e-65 219.3 0.0 3.0 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 GAK63310.1 - 7.8e-07 28.8 0.1 1.5e-05 24.7 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAK63310.1 - 0.00038 20.4 0.0 0.31 10.9 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase MeaB PF03308.16 GAK63310.1 - 0.0006 18.9 0.0 0.068 12.1 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAK63310.1 - 0.00064 20.1 0.1 0.0024 18.3 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAK63310.1 - 0.00064 20.0 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAK63310.1 - 0.0011 19.0 0.0 0.015 15.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK63310.1 - 0.0013 18.3 0.0 0.0047 16.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.12 GAK63310.1 - 0.003 17.5 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 GAK63310.1 - 0.0044 17.6 0.0 0.014 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 GAK63310.1 - 0.0053 16.4 0.0 0.56 9.8 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 GAK63310.1 - 0.0091 16.1 1.3 0.24 11.5 0.0 2.5 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 GAK63310.1 - 0.019 14.5 0.1 0.33 10.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 GAK63310.1 - 0.021 14.4 0.0 0.74 9.4 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 GAK63310.1 - 0.03 14.5 0.2 0.03 14.5 0.2 2.8 3 1 0 3 3 3 0 AAA domain G-alpha PF00503.20 GAK63310.1 - 0.032 13.4 0.2 2.4 7.2 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 GAK63310.1 - 0.037 14.0 0.0 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 GAK63310.1 - 0.041 14.3 0.0 0.37 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase PPV_E1_C PF00519.17 GAK63310.1 - 0.061 12.2 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase CNDH2_M PF16869.5 GAK63310.1 - 0.067 13.9 2.1 0.14 12.9 0.6 2.0 2 0 0 2 2 2 0 PF16858 NB-ARC PF00931.22 GAK63310.1 - 0.098 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 GAK63310.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 GAK63310.1 - 0.12 11.6 0.1 0.21 10.8 0.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Septin PF00735.18 GAK63310.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Septin Thymidylate_kin PF02223.17 GAK63310.1 - 0.17 11.6 0.5 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase KTI12 PF08433.10 GAK63310.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zn_clus PF00172.18 GAK63311.1 - 8.3e-07 29.0 9.7 1.5e-06 28.2 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UMP1 PF05348.11 GAK63312.1 - 1.4e-35 122.0 0.6 2e-35 121.6 0.5 1.2 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 rRNA_proc-arch PF13234.6 GAK63313.1 - 1.8e-87 293.7 0.0 2.8e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GAK63313.1 - 5.7e-54 182.2 1.8 2e-53 180.4 1.8 2.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 GAK63313.1 - 6.5e-20 71.6 0.0 3.1e-18 66.2 0.0 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK63313.1 - 1.1e-06 29.0 0.0 5.6e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK63313.1 - 0.00041 20.4 0.0 0.00088 19.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CENP-F_leu_zip PF10473.9 GAK63313.1 - 0.028 14.4 0.5 0.028 14.4 0.5 2.6 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 5_nucleotid_C PF02872.18 GAK63314.1 - 2.4e-28 99.3 0.0 3.1e-22 79.5 0.0 2.5 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 GAK63314.1 - 1.4e-07 32.3 0.1 3.4e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Syntaxin-6_N PF09177.11 GAK63315.1 - 5.6e-18 65.3 0.0 5.6e-18 65.3 0.0 3.1 4 0 0 4 4 4 1 Syntaxin 6, N-terminal AIP3 PF03915.13 GAK63315.1 - 0.0097 15.0 0.1 0.02 14.0 0.0 1.6 1 1 0 1 1 1 1 Actin interacting protein 3 Spc7 PF08317.11 GAK63315.1 - 0.13 11.1 0.2 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein SNARE PF05739.19 GAK63315.1 - 0.3 11.1 1.3 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 SNARE domain HSBP1 PF06825.12 GAK63316.1 - 3.5e-17 62.0 1.6 4.3e-17 61.7 1.6 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 GAK63316.1 - 0.012 15.9 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 GAK63316.1 - 0.04 14.0 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 GAK63316.1 - 0.041 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region UPF0184 PF03670.13 GAK63316.1 - 0.087 13.2 0.1 0.24 11.8 0.1 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DELLA PF12041.8 GAK63316.1 - 0.1 12.5 0.5 0.94 9.4 0.1 2.3 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal SF-assemblin PF06705.11 GAK63316.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin CHDCT2 PF08074.11 GAK63316.1 - 0.12 12.6 0.2 0.14 12.3 0.2 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Calpain_inhib PF00748.19 GAK63316.1 - 0.12 12.9 4.9 0.13 12.7 4.9 1.2 1 0 0 1 1 1 0 Calpain inhibitor T3SS_needle_F PF09392.10 GAK63316.1 - 0.17 12.1 1.8 2.1 8.6 0.1 2.5 2 1 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF FliD_N PF02465.18 GAK63316.1 - 9.8 7.0 11.7 4.7 8.0 0.1 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PPTA PF01239.22 GAK63317.1 - 2.4e-30 103.3 25.1 2.8e-08 33.2 0.6 6.1 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 GAK63317.1 - 0.0014 18.8 0.1 0.21 12.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat BolA PF01722.18 GAK63318.1 - 1.2e-26 92.7 0.2 2.5e-26 91.8 0.2 1.5 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L9_N PF01281.19 GAK63318.1 - 3e-09 36.3 0.0 5.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain polyprenyl_synt PF00348.17 GAK63319.1 - 8.8e-63 211.7 0.0 7.6e-56 189.0 0.0 2.6 2 1 0 2 2 2 2 Polyprenyl synthetase Mrr_N PF14338.6 GAK63319.1 - 0.14 12.3 0.0 0.51 10.5 0.0 2.0 1 0 0 1 1 1 0 Mrr N-terminal domain rhaM PF05336.13 GAK63320.1 - 6.2e-20 71.3 0.0 7.2e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Pkinase PF00069.25 GAK63321.1 - 3.1e-58 197.2 0.0 4.6e-39 134.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63321.1 - 6e-25 88.0 0.0 7.7e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 GAK63321.1 - 8e-10 38.9 0.0 1.6e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 GAK63321.1 - 7e-08 32.1 1.0 2e-05 24.1 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 GAK63321.1 - 0.0044 17.0 0.1 0.0044 17.0 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 GAK63321.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 GAK63321.1 - 0.027 14.7 0.0 0.08 13.2 0.0 1.8 2 0 0 2 2 1 0 PAS domain PAS_3 PF08447.12 GAK63321.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 GAK63321.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 GAK63321.1 - 0.15 11.6 0.0 22 4.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAK63321.1 - 0.28 10.1 0.0 0.48 9.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Gly_transf_sug PF04488.15 GAK63322.1 - 2.2e-21 76.3 0.0 4.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Mito_carr PF00153.27 GAK63323.1 - 3.5e-80 264.1 0.2 1.4e-26 92.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAK63323.1 - 0.048 12.8 0.6 1.1 8.4 0.0 3.1 3 1 1 4 4 4 0 Gammaproteobacterial serine protease PrcB_C PF14343.6 GAK63323.1 - 0.16 12.1 0.2 62 3.8 0.0 3.2 3 0 0 3 3 3 0 PrcB C-terminal Amidase PF01425.21 GAK63324.1 - 9.1e-97 324.8 0.0 1.6e-96 324.0 0.0 1.4 1 1 0 1 1 1 1 Amidase ERG4_ERG24 PF01222.17 GAK63325.1 - 2.7e-124 415.2 20.8 3.2e-124 415.0 20.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4112 PF13430.6 GAK63325.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Ribosomal_L29e PF01779.17 GAK63328.1 - 5.4e-21 74.6 7.1 1.4e-20 73.3 7.1 1.7 1 0 0 1 1 1 1 Ribosomal L29e protein family Glyco_hydro_125 PF06824.11 GAK63329.1 - 9.4e-145 482.6 0.0 1.2e-144 482.3 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) PHD PF00628.29 GAK63330.1 - 7.4e-12 45.0 16.1 3.5e-07 30.0 2.8 3.8 4 0 0 4 4 4 2 PHD-finger PHF12_MRG_bd PF16737.5 GAK63330.1 - 0.033 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain zf-PHD-like PF15446.6 GAK63330.1 - 2.5 7.7 5.0 6.1 6.4 2.0 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Vps51 PF08700.11 GAK63331.1 - 5.7e-12 45.6 0.0 2.8e-11 43.4 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 ApoLp-III PF07464.11 GAK63331.1 - 0.037 14.1 2.1 3.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) HofP PF10748.9 GAK63331.1 - 0.15 11.6 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 DNA utilization proteins HofP Pro_isomerase PF00160.21 GAK63332.1 - 1.6e-53 181.2 0.0 1.7e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Histone_H2A_C PF16211.5 GAK63333.1 - 1.9e-18 65.9 1.1 3.6e-18 65.0 1.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAK63333.1 - 5.8e-18 65.5 0.0 7.4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAK63333.1 - 9e-06 25.9 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAK63334.1 - 2.1e-22 79.9 1.1 3.4e-22 79.2 1.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAK63334.1 - 1.5e-05 25.2 0.1 1.5e-05 25.2 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAK63334.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 GAK63334.1 - 0.24 11.1 1.4 0.8 9.3 0.2 2.3 2 1 0 2 2 2 0 Replication protein C N-terminal domain Snf7 PF03357.21 GAK63335.1 - 2.1e-30 105.6 18.8 2.1e-30 105.6 18.8 1.4 2 0 0 2 2 2 1 Snf7 APG6_N PF17675.1 GAK63335.1 - 0.027 15.0 4.0 0.027 15.0 4.0 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region Eno-Rase_FAD_bd PF07055.12 GAK63335.1 - 0.087 13.2 0.9 0.28 11.6 0.1 2.2 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain RBFA PF02033.18 GAK63335.1 - 5.9 7.4 8.3 5.5 7.5 5.3 2.1 1 1 1 2 2 2 0 Ribosome-binding factor A MIP PF00230.20 GAK63338.1 - 1e-47 162.8 7.8 1.2e-47 162.5 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein PPI_Ypi1 PF07491.11 GAK63339.1 - 1.4e-22 79.3 11.0 1.4e-22 79.3 11.0 3.2 2 2 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.14 GAK63339.1 - 0.028 12.7 10.5 0.033 12.5 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 GAK63339.1 - 2 8.4 5.7 2.3 8.2 5.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 GAK63340.1 - 5.5e-26 91.5 0.0 1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63340.1 - 3.2e-13 49.6 0.0 6.1e-12 45.4 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK63340.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.6 GAK63341.1 - 5.7e-05 23.4 5.0 5.7e-05 23.4 5.0 2.1 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 GAK63341.1 - 0.00013 21.5 0.4 0.00026 20.6 0.4 1.5 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.8 GAK63341.1 - 0.0022 18.1 3.2 0.0045 17.1 3.2 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 GAK63341.1 - 0.0081 16.2 1.2 0.02 14.9 1.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAK63341.1 - 0.089 12.8 4.8 0.087 12.8 3.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 GAK63341.1 - 0.17 12.2 1.6 0.45 10.9 1.6 1.7 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 GAK63341.1 - 0.25 11.0 2.5 0.65 9.7 2.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAK63341.1 - 0.3 11.2 4.7 0.63 10.2 4.7 1.6 1 0 0 1 1 1 0 RING-variant domain DUF4407 PF14362.6 GAK63342.1 - 0.0025 17.2 10.4 0.0038 16.6 10.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HrpB7 PF09486.10 GAK63342.1 - 0.14 12.6 13.3 0.16 12.4 6.2 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Endonuc_Holl PF10107.9 GAK63342.1 - 0.24 11.3 1.2 1.1 9.1 0.2 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Laminin_II PF06009.12 GAK63342.1 - 0.29 11.2 5.9 0.5 10.4 1.8 2.9 3 0 0 3 3 3 0 Laminin Domain II Ribosomal_L29 PF00831.23 GAK63342.1 - 0.31 11.0 2.7 35 4.5 0.0 3.7 4 0 0 4 4 3 0 Ribosomal L29 protein Uso1_p115_C PF04871.13 GAK63342.1 - 0.66 10.3 10.0 0.21 11.9 5.8 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 GAK63342.1 - 0.89 10.0 7.5 1.3 9.4 6.6 1.9 1 1 0 1 1 1 0 Fez1 DUF4200 PF13863.6 GAK63342.1 - 1.1 9.7 11.6 0.22 11.9 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-H PF05837.12 GAK63342.1 - 2.1 8.8 6.3 2 8.8 2.6 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 GAK63342.1 - 4.3 7.4 11.2 0.22 11.6 4.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 GAK63342.1 - 5.1 6.8 12.5 1.1 9.0 8.1 1.8 1 1 0 2 2 2 0 Ezrin/radixin/moesin family PRKG1_interact PF15898.5 GAK63342.1 - 6.9 7.6 10.3 0.62 11.0 2.7 2.8 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain zf-C4H2 PF10146.9 GAK63342.1 - 7.8 6.7 7.1 16 5.7 3.9 2.5 2 1 0 2 2 2 0 Zinc finger-containing protein Seryl_tRNA_N PF02403.22 GAK63342.1 - 9.7 6.5 10.1 1.9 8.8 5.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Glyco_transf_24 PF18404.1 GAK63344.1 - 6.3e-144 478.3 1.8 1e-143 477.6 1.8 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GAK63344.1 - 3.3e-56 191.1 0.0 6.1e-53 180.4 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GAK63344.1 - 2.4e-35 121.0 0.0 6e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 GAK63344.1 - 5.3e-32 110.6 0.2 1.7e-31 108.9 0.2 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 GAK63344.1 - 1.2e-30 106.8 1.8 2.3e-30 105.9 0.3 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 GAK63344.1 - 6.5e-13 49.1 1.9 6.3e-12 45.9 0.0 3.2 4 0 0 4 4 4 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 GAK63344.1 - 9.4e-07 28.6 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DPBB_1 PF03330.18 GAK63346.1 - 6.8e-08 32.7 0.1 1.8e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 Lytic transglycolase Pkinase PF00069.25 GAK63347.1 - 1.5e-64 217.9 0.0 2.7e-64 217.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63347.1 - 4.6e-36 124.4 0.0 2.4e-34 118.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 GAK63347.1 - 0.0052 16.4 0.2 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 GAK63347.1 - 0.0073 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAK63347.1 - 0.019 14.3 0.0 0.14 11.4 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 GAK63347.1 - 0.022 13.8 0.1 0.065 12.3 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 GAK63347.1 - 0.043 13.7 0.0 0.26 11.2 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAK63347.1 - 0.059 12.3 0.2 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain GST_N_2 PF13409.6 GAK63348.1 - 1.4e-19 70.1 0.1 2.5e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK63348.1 - 7.1e-13 48.4 0.0 2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAK63348.1 - 0.00047 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAK63348.1 - 0.016 15.6 0.2 0.075 13.5 0.2 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Adeno_E4 PF05385.11 GAK63348.1 - 0.047 13.8 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein RasGEF PF00617.19 GAK63349.1 - 2.5e-51 174.4 0.0 4.8e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAK63349.1 - 1.1e-23 83.4 0.0 2.8e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 GAK63349.1 - 2.7e-14 52.6 0.0 5.6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAK63349.1 - 9.9e-14 50.9 0.1 2.2e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAK63349.1 - 1.5e-12 46.9 0.0 2.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain US30 PF17624.2 GAK63349.1 - 0.048 12.7 0.1 0.094 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function T3SS_TC PF06511.11 GAK63349.1 - 4.7 6.5 8.8 0.38 10.1 2.8 2.2 2 0 0 2 2 2 0 Type III secretion systems tip complex components Ribosomal_60s PF00428.19 GAK63349.1 - 5 7.8 5.7 39 4.9 0.1 4.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Nucleo_P87 PF07267.11 GAK63349.1 - 6.8 5.4 5.4 5.1 5.8 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 2-oxoacid_dh PF00198.23 GAK63350.1 - 5.6e-78 261.6 0.1 7.8e-78 261.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAK63350.1 - 2e-19 69.2 2.1 3.8e-19 68.3 2.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 GAK63350.1 - 1.2e-05 26.0 0.3 0.16 12.7 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 GAK63350.1 - 1.3e-05 24.9 0.1 0.0088 15.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 GAK63350.1 - 0.0011 18.9 1.0 0.0023 17.8 1.0 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein PI3K_1B_p101 PF10486.9 GAK63350.1 - 0.025 12.4 10.1 0.029 12.1 10.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RebB PF11747.8 GAK63350.1 - 0.044 13.9 0.8 0.12 12.5 0.8 1.7 1 0 0 1 1 1 0 Killing trait Apt1 PF10351.9 GAK63350.1 - 0.095 11.5 17.9 0.14 11.0 17.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM76 PF16046.5 GAK63350.1 - 0.13 11.6 15.3 0.4 10.0 11.0 2.1 2 0 0 2 2 2 0 FAM76 protein Presenilin PF01080.17 GAK63350.1 - 0.14 10.9 12.0 0.22 10.2 12.0 1.3 1 0 0 1 1 1 0 Presenilin HlyD_D23 PF16576.5 GAK63350.1 - 0.18 11.0 2.3 0.3 10.3 0.2 2.2 2 1 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Lin-8 PF03353.15 GAK63350.1 - 0.41 10.2 11.0 0.57 9.7 11.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TAF4 PF05236.14 GAK63350.1 - 0.46 10.2 18.3 0.67 9.7 17.8 1.5 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Macoilin PF09726.9 GAK63350.1 - 1.6 7.2 14.0 1.9 6.9 14.0 1.2 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 GAK63350.1 - 3.8 6.1 15.4 6.5 5.3 15.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 GAK63350.1 - 4.5 6.3 10.1 6.6 5.7 10.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein GREB1 PF15782.5 GAK63350.1 - 9.6 3.2 14.6 12 2.9 14.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YabA PF06156.13 GAK63353.1 - 1.8 9.3 4.7 7 7.3 1.6 2.7 2 0 0 2 2 2 0 Initiation control protein YabA HOOK PF05622.12 GAK63353.1 - 2.7 6.0 17.2 0.12 10.5 6.2 2.4 1 1 1 2 2 2 0 HOOK protein zf-Di19 PF05605.12 GAK63354.1 - 1.8e-07 31.3 13.2 0.0016 18.7 0.0 4.5 4 1 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding Cys_rich_CPXG PF14255.6 GAK63354.1 - 0.049 13.5 9.3 1.2 9.1 0.1 4.2 4 0 0 4 4 4 0 Cysteine-rich CPXCG Rad50_zn_hook PF04423.14 GAK63354.1 - 0.31 10.9 3.0 0.61 10.0 0.2 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif Ogr_Delta PF04606.12 GAK63354.1 - 0.72 9.9 11.1 7.2 6.7 0.2 4.7 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.6 GAK63354.1 - 1 10.4 13.6 4.2 8.5 0.1 5.2 4 1 1 5 5 5 0 C2H2-type zinc finger Forkhead PF00250.18 GAK63355.1 - 1.5e-20 73.2 0.0 2.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Amidohydro_2 PF04909.14 GAK63356.1 - 1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 GAK63356.1 - 3.9e-07 29.7 0.0 7.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family FUN14 PF04930.15 GAK63357.1 - 1.5e-20 73.4 0.7 2.7e-20 72.6 0.4 1.6 2 0 0 2 2 2 1 FUN14 family LSM PF01423.22 GAK63360.1 - 7e-15 54.5 0.0 1.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 LSM domain PRELI PF04707.14 GAK63360.1 - 4.2e-13 49.4 2.9 0.00094 19.0 0.0 4.2 4 0 0 4 4 4 4 PRELI-like family Bromodomain PF00439.25 GAK63362.1 - 1.6e-19 69.8 0.0 2.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain MFS_1 PF07690.16 GAK63363.1 - 1.7e-24 86.4 12.3 3.9e-24 85.2 11.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIID_30kDa PF03540.13 GAK63364.1 - 2e-24 85.3 0.0 4e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.28 GAK63364.1 - 2.6e-08 34.2 0.0 2.3e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain Ribosomal_60s PF00428.19 GAK63364.1 - 0.0098 16.5 13.7 0.1 13.2 0.1 4.1 3 1 0 3 3 3 2 60s Acidic ribosomal protein FoP_duplication PF13865.6 GAK63364.1 - 0.048 14.2 1.6 0.14 12.7 1.6 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 F-112 PF09645.10 GAK63364.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 F-112 protein LMBR1 PF04791.16 GAK63365.1 - 0.04 12.8 1.4 0.06 12.3 0.4 1.8 2 1 0 2 2 2 0 LMBR1-like membrane protein HMG14_17 PF01101.18 GAK63365.1 - 0.099 13.6 0.2 0.15 13.0 0.2 1.2 1 0 0 1 1 1 0 HMG14 and HMG17 tRNA-synt_2d PF01409.20 GAK63366.1 - 1.9e-86 289.6 0.0 2.5e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GAK63366.1 - 1.8e-09 37.7 0.2 9.1e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 GAK63366.1 - 1.1e-07 31.6 0.0 0.0002 20.9 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 GAK63366.1 - 4e-05 22.8 0.2 0.00086 18.5 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 GAK63366.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 GAK63366.1 - 0.22 11.6 1.7 0.55 10.3 1.7 1.7 1 0 0 1 1 1 0 PheRS DNA binding domain 2 IBN_N PF03810.19 GAK63367.1 - 7.9e-09 35.3 1.0 2.6e-06 27.3 0.6 3.2 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAK63367.1 - 0.07 13.2 0.0 0.31 11.1 0.0 2.2 1 0 0 1 1 1 0 Exportin 1-like protein HEAT_2 PF13646.6 GAK63367.1 - 0.12 12.7 13.4 0.058 13.8 1.4 5.1 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 GAK63367.1 - 0.15 12.4 2.3 0.58 10.6 0.4 3.3 2 0 0 2 2 2 0 HEAT repeat G-patch PF01585.23 GAK63368.1 - 1.2e-11 44.3 1.4 1e-08 34.9 0.6 2.5 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.7 GAK63368.1 - 0.00027 21.0 1.0 0.054 13.6 0.3 2.6 2 0 0 2 2 2 2 G-patch domain Acetyltransf_1 PF00583.25 GAK63369.1 - 2.1e-13 50.5 0.0 2.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK63369.1 - 2.1e-05 24.8 0.0 6.2e-05 23.3 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK63369.1 - 0.0012 18.7 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 GAK63369.1 - 0.002 18.1 0.0 0.0027 17.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Alpha_E3_glycop PF01563.16 GAK63369.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Acetyltransf_CG PF14542.6 GAK63369.1 - 0.11 12.6 0.0 0.94 9.7 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Med20 PF08612.11 GAK63370.1 - 0.03 13.7 0.0 3.8 6.8 0.0 2.7 2 1 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex PNISR PF15996.5 GAK63370.1 - 6 7.1 16.0 0.28 11.4 7.1 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF410 PF04190.13 GAK63371.1 - 2.3e-64 217.7 0.0 2.7e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TetR_C_33 PF13305.6 GAK63371.1 - 1 10.1 8.3 3.6 8.4 0.1 3.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PROCN PF08083.11 GAK63372.1 - 7.4e-218 723.1 3.9 1.2e-217 722.5 3.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GAK63372.1 - 2e-120 400.6 0.4 3.6e-120 399.8 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 GAK63372.1 - 8.8e-84 279.2 0.5 2.8e-83 277.6 0.5 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 GAK63372.1 - 3.7e-82 273.7 3.8 8.5e-82 272.5 3.8 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 GAK63372.1 - 2.2e-63 212.3 0.0 4.7e-63 211.2 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 GAK63372.1 - 1.5e-46 156.7 0.5 3.4e-46 155.5 0.5 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 GAK63372.1 - 5.1e-40 136.2 0.0 1e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 GAK63372.1 - 0.0013 18.7 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ANAPC_CDC26 PF10471.9 GAK63374.1 - 3.6e-07 30.9 4.7 2.2e-06 28.4 4.7 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Wtap PF17098.5 GAK63375.1 - 0.0011 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family DUF1043 PF06295.12 GAK63375.1 - 0.011 15.7 0.2 0.022 14.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) HAP1_N PF04849.13 GAK63375.1 - 0.047 12.9 2.6 0.058 12.6 1.8 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region JAKMIP_CC3 PF16034.5 GAK63375.1 - 0.051 13.5 1.3 0.081 12.9 1.3 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain MAD PF05557.13 GAK63375.1 - 0.13 10.6 0.3 0.17 10.2 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Med2 PF11214.8 GAK63375.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 Tropomyosin PF00261.20 GAK63375.1 - 0.18 11.2 1.6 0.31 10.4 1.6 1.3 1 0 0 1 1 1 0 Tropomyosin WEMBL PF05701.11 GAK63375.1 - 0.41 9.3 4.9 0.054 12.2 0.7 1.5 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Pyr_redox_3 PF13738.6 GAK63376.1 - 1.7e-13 50.5 0.0 8.1e-11 41.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAK63376.1 - 2.5e-12 46.0 0.0 1.7e-06 26.8 0.0 3.7 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAK63376.1 - 2.9e-10 39.9 0.0 2e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAK63376.1 - 3e-06 26.6 0.1 0.00015 21.1 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAK63376.1 - 4.1e-06 26.9 0.1 0.00014 21.9 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 GAK63376.1 - 0.00029 20.6 0.3 0.012 15.3 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAK63376.1 - 0.0036 17.5 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 GAK63376.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus JAB PF01398.21 GAK63377.1 - 9.7e-32 109.4 0.0 1.7e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAK63377.1 - 2.6e-14 53.6 2.0 2.8e-14 53.5 0.7 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GAK63377.1 - 1.2e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 GAK63377.1 - 0.02 15.0 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Arf PF00025.21 GAK63378.1 - 8.6e-36 123.0 0.0 4.6e-25 88.1 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAK63378.1 - 3.1e-14 53.2 0.0 6e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAK63378.1 - 1.3e-13 50.9 0.0 6.2e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 GAK63378.1 - 5.1e-08 32.6 0.0 1.1e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAK63378.1 - 2.2e-06 27.2 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK63378.1 - 4.7e-06 26.7 0.0 9.5e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAK63378.1 - 2.5e-05 23.6 0.3 7e-05 22.2 0.1 1.7 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 GAK63378.1 - 0.0025 17.9 0.0 0.29 11.2 0.2 2.2 1 1 1 2 2 2 1 Dynamin family AAA_18 PF13238.6 GAK63378.1 - 0.074 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Vps52 PF04129.12 GAK63379.1 - 5.5e-34 117.8 0.0 4.7e-23 81.7 0.0 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family FTA4 PF13093.6 GAK63379.1 - 0.0034 17.3 5.9 0.16 11.9 0.2 2.4 2 0 0 2 2 2 2 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sec3_C PF09763.9 GAK63379.1 - 0.0034 15.8 0.0 0.0076 14.7 0.0 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec3 Kdo_hydroxy PF11004.8 GAK63379.1 - 0.032 13.5 0.0 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase MscS_porin PF12795.7 GAK63379.1 - 4.4 6.8 18.8 0.42 10.1 13.3 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pkinase PF00069.25 GAK63380.1 - 1.3e-65 221.4 0.0 2.1e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63380.1 - 9.8e-36 123.4 0.0 4.1e-25 88.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK63380.1 - 0.00073 18.9 0.3 0.0062 15.9 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 GAK63380.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 GAK63380.1 - 0.0051 16.8 0.0 0.024 14.6 0.0 2.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAK63380.1 - 0.057 12.2 0.3 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 GAK63380.1 - 0.12 12.0 0.3 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIC1 PF07064.13 GAK63381.1 - 1.1e-103 346.0 0.0 2.5e-103 344.9 0.0 1.6 1 1 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 GAK63381.1 - 2.4e-05 24.5 0.2 0.11 12.8 0.0 4.8 5 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQ-loop PF04193.14 GAK63382.1 - 5.9e-36 122.1 5.3 5.1e-19 67.8 0.3 2.5 2 0 0 2 2 2 2 PQ loop repeat Sre PF03125.18 GAK63382.1 - 0.13 11.4 0.7 0.19 10.8 0.7 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor ECH_1 PF00378.20 GAK63384.1 - 2.5e-18 66.3 0.4 4.7e-18 65.4 0.4 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 GAK63384.1 - 3.1e-05 24.2 0.0 7.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain SRP-alpha_N PF04086.13 GAK63384.1 - 1.6 8.6 8.9 2.7 7.8 8.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 GAK63386.1 - 1.4e-34 119.6 25.9 1.4e-34 119.6 25.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1294 PF06961.13 GAK63386.1 - 0.062 13.5 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Wzz PF02706.15 GAK63386.1 - 0.48 10.8 4.7 9.9 6.5 0.0 3.7 2 1 1 3 3 3 0 Chain length determinant protein MMM1 PF10296.9 GAK63387.1 - 5.6e-08 32.2 0.0 2.2e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 CIAPIN1 PF05093.13 GAK63388.1 - 1.4e-32 112.1 4.6 2.9e-32 111.1 4.6 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 GAK63388.1 - 7.9e-07 29.4 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus WBS_methylT PF12589.8 GAK63389.1 - 3.2e-22 79.1 9.0 5.8e-22 78.2 9.0 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 GAK63389.1 - 7.5e-11 42.5 0.0 1.5e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK63389.1 - 3.1e-09 37.4 0.0 6.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK63389.1 - 2.1e-06 27.7 0.0 3.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK63389.1 - 3.2e-06 27.8 0.0 9.8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK63389.1 - 0.00026 20.8 0.0 0.00055 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 GAK63389.1 - 0.0055 17.0 0.0 0.06 13.7 0.0 2.2 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.18 GAK63389.1 - 0.063 13.0 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 DNA methylase AFG1_ATPase PF03969.16 GAK63390.1 - 2.2e-55 188.0 0.2 1.9e-49 168.5 0.0 4.3 2 1 1 3 3 3 2 AFG1-like ATPase DnaJ PF00226.31 GAK63390.1 - 6.9e-19 67.7 0.5 2e-18 66.3 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain AAA_16 PF13191.6 GAK63390.1 - 3.7e-07 30.7 0.1 2e-05 25.0 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAK63390.1 - 0.02 15.2 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAK63390.1 - 0.027 15.0 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAK63390.1 - 0.036 14.4 0.0 7.8 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 GAK63390.1 - 0.088 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAK63390.1 - 0.17 12.3 0.0 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GPI-anchored PF10342.9 GAK63392.1 - 0.11 13.2 1.9 0.15 12.8 0.6 2.0 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4493 PF14900.6 GAK63392.1 - 0.32 10.8 2.9 2 8.2 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4493) Fungal_trans PF04082.18 GAK63393.1 - 4.9e-30 104.5 0.0 8e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK63393.1 - 2.4e-08 34.0 9.5 4e-08 33.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAK63394.1 - 6.3e-07 29.0 0.2 0.016 14.7 0.5 3.1 2 1 0 2 2 2 2 short chain dehydrogenase Peptidase_S9 PF00326.21 GAK63396.1 - 3.9e-40 137.6 0.4 1e-27 97.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family PIG-H PF10181.9 GAK63396.1 - 1.1e-12 47.6 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DLH PF01738.18 GAK63396.1 - 6.8e-08 32.3 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 GAK63396.1 - 2.5e-05 24.3 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 GAK63396.1 - 7.1e-05 22.2 3.6 0.00019 20.8 0.0 3.0 4 0 0 4 4 4 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 GAK63396.1 - 0.00084 19.4 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 GAK63396.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 GAK63396.1 - 0.058 13.0 2.9 0.3 10.7 0.0 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Kinesin PF00225.23 GAK63397.1 - 2.1e-113 378.7 0.0 3e-113 378.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAK63397.1 - 2.3e-26 92.5 0.0 5.4e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Herpes_UL6 PF01763.16 GAK63397.1 - 0.009 14.6 3.1 0.017 13.6 3.1 1.4 1 0 0 1 1 1 1 Herpesvirus UL6 like Filament PF00038.21 GAK63397.1 - 0.027 14.0 10.4 0.05 13.2 10.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein GPS2_interact PF15784.5 GAK63397.1 - 0.12 12.8 1.3 0.38 11.2 1.3 1.9 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain ADIP PF11559.8 GAK63397.1 - 0.17 12.0 8.0 0.46 10.6 0.0 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.11 GAK63397.1 - 1.7 8.7 6.3 0.81 9.7 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) YabA PF06156.13 GAK63397.1 - 1.9 9.2 5.6 2.2 9.0 2.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 GAK63397.1 - 3.2 5.6 3.9 5.7 4.7 3.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eRF1_1 PF03463.15 GAK63398.1 - 4.4e-51 172.2 0.0 6.1e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 GAK63398.1 - 2.8e-23 82.6 0.0 5.4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 GAK63398.1 - 4.8e-21 75.5 0.0 7.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 L51_S25_CI-B8 PF05047.16 GAK63399.1 - 9.6e-14 51.0 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RAI16-like PF10257.9 GAK63400.1 - 8.4e-53 179.5 0.0 1.3e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ATP12 PF07542.11 GAK63401.1 - 7.5e-38 129.5 0.0 1.3e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Pex24p PF06398.11 GAK63402.1 - 7.4e-25 87.7 14.8 9.3e-25 87.4 5.1 3.1 2 2 0 2 2 2 2 Integral peroxisomal membrane peroxin PIG-S PF10510.9 GAK63403.1 - 4.3e-121 405.3 1.2 5.1e-121 405.0 1.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Aldo_ket_red PF00248.21 GAK63404.1 - 6.6e-43 147.0 0.0 4.3e-41 141.0 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.23 GAK63405.1 - 0.00014 21.8 0.8 0.00025 21.0 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 GAK63405.1 - 0.093 12.5 0.4 0.25 11.1 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle FUSC_2 PF13515.6 GAK63406.1 - 4.6e-23 81.7 4.9 4.6e-23 81.7 4.9 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 GAK63406.1 - 1.3e-14 53.9 5.5 1.2e-11 44.2 0.2 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 GAK63406.1 - 4.2e-12 45.4 14.7 4.5e-11 42.0 5.9 3.4 3 1 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 GAK63406.1 - 1.7e-09 37.9 0.0 4.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 GAK63406.1 - 0.0083 16.3 0.5 0.0083 16.3 0.5 3.1 3 1 0 3 3 3 1 Aromatic acid exporter family member 1 Phage_holin_3_6 PF07332.11 GAK63406.1 - 0.063 13.3 7.0 0.15 12.1 5.7 2.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III FUSC-like PF12805.7 GAK63406.1 - 0.077 12.1 6.7 1.5 7.8 2.2 2.6 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Zn_clus PF00172.18 GAK63407.1 - 0.00069 19.7 7.5 0.002 18.2 7.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC4_C PF14629.6 GAK63407.1 - 0.027 13.8 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Sec39 PF08314.11 GAK63408.1 - 2.6e-27 95.7 0.0 4.3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 PIN_3 PF13470.6 GAK63408.1 - 0.13 13.0 2.0 1.2 9.9 1.4 3.1 2 0 0 2 2 2 0 PIN domain Med21 PF11221.8 GAK63409.1 - 4.4e-23 82.1 5.4 5.9e-23 81.7 5.4 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Uso1_p115_C PF04871.13 GAK63409.1 - 0.021 15.2 2.0 0.03 14.7 2.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 GAK63409.1 - 0.027 13.4 5.5 0.0093 14.9 3.2 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin_2 PF14523.6 GAK63409.1 - 0.032 14.6 0.7 0.054 13.9 0.7 1.3 1 0 0 1 1 1 0 Syntaxin-like protein KfrA_N PF11740.8 GAK63409.1 - 0.069 13.8 4.7 0.12 13.0 4.7 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term KxDL PF10241.9 GAK63409.1 - 0.08 13.2 2.8 0.16 12.3 2.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.8 GAK63409.1 - 0.083 13.1 3.3 0.19 12.0 3.3 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.8 GAK63409.1 - 0.098 12.8 3.0 0.063 13.4 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) LPP PF04728.13 GAK63409.1 - 0.86 10.0 3.8 3.8 8.0 1.4 2.7 1 1 2 3 3 3 0 Lipoprotein leucine-zipper ICMT PF04140.14 GAK63410.1 - 1.8e-25 89.2 0.3 1.8e-25 89.2 0.3 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAK63410.1 - 7.5e-11 42.4 0.9 7.5e-11 42.4 0.9 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAK63410.1 - 0.00015 21.4 1.9 0.00023 20.7 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 GAK63410.1 - 0.00023 20.8 5.3 0.00023 20.8 5.3 2.1 1 1 1 2 2 2 1 NnrU protein TRP PF06011.12 GAK63411.1 - 4.4e-38 131.1 4.2 4.4e-38 131.1 4.2 1.9 1 1 1 2 2 2 1 Transient receptor potential (TRP) ion channel DUF3808 PF10300.9 GAK63412.1 - 8.2e-82 275.4 0.3 1.8e-81 274.3 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Zn_clus PF00172.18 GAK63412.1 - 0.0052 16.9 11.6 0.011 15.8 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-P PF13096.6 GAK63412.1 - 0.23 11.1 0.0 0.43 10.3 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P TPR_8 PF13181.6 GAK63412.1 - 4.8 7.6 6.8 2.6 8.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 GAK63413.1 - 8.4e-20 70.7 0.0 2.2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Acetyltransf_2 PF00797.17 GAK63414.1 - 2.1e-23 83.4 0.6 5e-22 78.9 0.1 2.7 2 1 0 2 2 2 1 N-acetyltransferase ANAPC4_WD40 PF12894.7 GAK63415.1 - 6.5e-05 23.1 0.1 0.58 10.5 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAK63415.1 - 0.094 13.2 4.0 0.39 11.3 0.1 3.9 6 0 0 6 6 6 0 PQQ-like domain WD40 PF00400.32 GAK63415.1 - 0.26 12.2 22.4 1.1 10.3 0.1 5.4 3 2 1 4 4 4 0 WD domain, G-beta repeat Cactin_mid PF10312.9 GAK63416.1 - 1.1e-62 211.3 7.5 1.1e-62 211.3 7.5 2.1 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 GAK63416.1 - 1.4e-61 206.0 5.7 2.4e-61 205.2 5.7 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein AD PF09793.9 GAK63417.1 - 3.5e-19 68.7 0.0 8.2e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain DUF3145 PF11343.8 GAK63417.1 - 0.055 13.0 0.1 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) NPC1_N PF16414.5 GAK63418.1 - 3.3e-76 256.1 7.7 4.9e-76 255.5 7.7 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 GAK63418.1 - 1.4e-60 205.3 0.8 3.8e-31 108.0 0.2 3.0 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 GAK63418.1 - 5.6e-42 143.2 11.1 1.2e-20 73.9 0.4 3.5 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 GAK63418.1 - 0.0012 18.8 1.2 0.0022 17.9 1.2 1.4 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 GAK63418.1 - 0.036 11.7 1.1 0.051 11.2 1.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family HemY_N PF07219.13 GAK63418.1 - 0.71 10.1 5.3 5.3 7.3 0.4 3.4 2 1 0 3 3 3 0 HemY protein N-terminus CobD_Cbib PF03186.13 GAK63419.1 - 0.054 12.7 0.1 0.087 12.0 0.1 1.2 1 0 0 1 1 1 0 CobD/Cbib protein S_4TM PF18159.1 GAK63419.1 - 0.076 12.3 0.4 0.11 11.8 0.4 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain tRNA_anti-codon PF01336.25 GAK63421.1 - 0.056 13.4 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain SelB-wing_1 PF09105.10 GAK63421.1 - 0.067 13.2 0.6 2.7 8.0 0.1 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix CHZ PF09649.10 GAK63422.1 - 1.5e-11 43.5 0.2 1.5e-11 43.5 0.2 3.4 4 1 0 4 4 4 1 Histone chaperone domain CHZ DNA_pol_phi PF04931.13 GAK63422.1 - 4.7 5.2 30.6 5.1 5.1 30.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpb4 PF03874.16 GAK63423.1 - 1.5e-27 96.4 0.6 1.9e-27 96.0 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.32 GAK63424.1 - 2.2e-26 91.6 9.8 1e-06 29.4 0.0 6.7 6 1 0 6 6 6 4 WD domain, G-beta repeat Sof1 PF04158.14 GAK63424.1 - 4.9e-26 90.8 11.7 7.6e-26 90.2 11.7 1.3 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 GAK63424.1 - 1.9e-05 24.8 0.0 7.4 6.9 0.0 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CBFB_NFYA PF02045.15 GAK63425.1 - 7.7e-22 77.7 12.4 7.7e-22 77.7 12.4 2.9 2 1 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ThuA PF06283.11 GAK63426.1 - 1e-43 150.0 0.0 1.3e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation BPL_N PF09825.9 GAK63426.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3446 PF11928.8 GAK63426.1 - 0.17 12.2 9.3 0.12 12.7 6.8 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Sigma_reg_C PF13791.6 GAK63426.1 - 0.21 11.8 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator C-terminal Sporozoite_P67 PF05642.11 GAK63426.1 - 1 7.3 8.7 1.4 6.9 8.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kelch_4 PF13418.6 GAK63427.1 - 1.2e-31 108.4 4.6 7.1e-07 29.1 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 GAK63427.1 - 3.7e-27 94.0 4.7 7.5e-07 29.3 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAK63427.1 - 3.1e-19 68.6 4.0 1.7e-05 24.7 0.0 6.0 6 0 0 6 6 6 3 Kelch motif DUF4110 PF13422.6 GAK63427.1 - 1.5e-18 66.6 0.5 1.5e-18 66.6 0.5 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 GAK63427.1 - 1.4e-15 56.9 8.0 0.0004 20.6 0.0 5.8 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GAK63427.1 - 1.8e-14 53.1 3.0 5.5e-05 22.7 0.0 5.1 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAK63427.1 - 2.3e-12 46.3 0.7 0.019 15.0 0.0 5.2 6 0 0 6 6 6 3 Kelch motif BUD22 PF09073.10 GAK63427.1 - 0.00089 18.7 30.9 0.0023 17.3 18.7 2.4 2 0 0 2 2 2 2 BUD22 Acetyltransf_6 PF13480.7 GAK63427.1 - 0.11 12.6 3.0 0.19 11.9 0.1 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DAP PF15228.6 GAK63427.1 - 2.7 9.2 19.6 0.45 11.7 3.5 2.7 2 0 0 2 2 2 0 Death-associated protein MCM_bind PF09739.9 GAK63427.1 - 3.3 6.0 12.9 0.021 13.3 1.0 2.2 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor ECH_1 PF00378.20 GAK63428.1 - 6.8e-20 71.4 0.0 1e-17 64.3 0.0 2.5 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK63428.1 - 2.6e-09 37.0 0.0 3.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1731 PF08338.11 GAK63428.1 - 0.037 13.8 0.3 0.093 12.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Vac17 PF17321.2 GAK63430.1 - 0.025 14.1 2.2 0.029 13.9 2.2 1.0 1 0 0 1 1 1 0 Vacuole-related protein 17 DUF4169 PF13770.6 GAK63430.1 - 0.044 14.0 0.5 0.11 12.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) Actin PF00022.19 GAK63431.1 - 2.5e-126 421.6 0.0 7.2e-126 420.1 0.0 1.7 1 1 0 1 1 1 1 Actin adh_short_C2 PF13561.6 GAK63431.1 - 5.3e-62 209.4 0.8 9.2e-62 208.7 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1077 PF06417.12 GAK63431.1 - 1e-44 151.3 0.6 2.2e-44 150.2 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) adh_short PF00106.25 GAK63431.1 - 2.9e-43 147.6 0.6 5.3e-43 146.7 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase AhpC-TSA_2 PF13911.6 GAK63431.1 - 2.3e-11 43.8 0.0 1e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme KR PF08659.10 GAK63431.1 - 2.5e-11 43.8 2.3 6.1e-11 42.5 2.3 1.5 1 0 0 1 1 1 1 KR domain PALP PF00291.25 GAK63431.1 - 0.058 12.8 2.5 0.039 13.4 0.5 1.7 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Redoxin PF08534.10 GAK63431.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Redoxin DUF4658 PF15555.6 GAK63431.1 - 0.15 12.1 0.3 0.98 9.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4658) DUF4072 PF13284.6 GAK63431.1 - 2.6 8.5 5.9 12 6.5 5.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) DHQ_synthase PF01761.20 GAK63432.1 - 1.8e-48 165.0 0.0 2.4e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 GAK63432.1 - 8.5e-11 42.0 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Rad17 PF03215.15 GAK63435.1 - 1.1e-19 71.1 0.0 9.4e-19 68.1 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GAK63435.1 - 0.0038 17.6 5.9 0.0046 17.3 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_assoc_2 PF16193.5 GAK63435.1 - 0.013 15.9 0.1 0.048 14.0 0.1 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_22 PF13401.6 GAK63435.1 - 0.076 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IBN_N PF03810.19 GAK63436.1 - 3.4e-16 58.9 0.0 1.2e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 GAK63436.1 - 7.2e-07 28.3 0.0 1.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cse1 HEAT PF02985.22 GAK63436.1 - 0.03 14.6 0.3 3.6 8.1 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat Xpo1 PF08389.12 GAK63436.1 - 0.067 13.3 0.0 0.35 10.9 0.0 2.3 1 0 0 1 1 1 0 Exportin 1-like protein IL17_R_N PF15037.6 GAK63436.1 - 0.073 12.0 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region EF_assoc_2 PF08356.12 GAK63436.1 - 0.14 12.1 0.1 0.45 10.5 0.1 1.8 1 0 0 1 1 1 0 EF hand associated Inhibitor_I9 PF05922.16 GAK63436.1 - 0.15 12.8 0.0 2.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Peptidase inhibitor I9 Translin PF01997.16 GAK63437.1 - 4.9e-38 131.2 0.1 5.8e-38 130.9 0.1 1.1 1 0 0 1 1 1 1 Translin family Spc29 PF17082.5 GAK63437.1 - 0.0033 17.3 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 BLOC1_2 PF10046.9 GAK63437.1 - 0.04 14.2 0.4 3.3 8.1 0.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L1 PF00687.21 GAK63438.1 - 6.2e-53 179.6 0.0 1.1e-52 178.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Motile_Sperm PF00635.26 GAK63439.1 - 9.7e-26 89.8 0.2 1.5e-25 89.1 0.2 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 GAK63439.1 - 4.1e-06 26.9 0.2 8.3e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1192 PF06698.11 GAK63439.1 - 0.048 13.7 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1811 PF08838.10 GAK63439.1 - 0.067 13.4 0.1 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) ATG16 PF08614.11 GAK63439.1 - 2.7 8.2 5.3 2.4 8.3 4.1 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4336 PF14234.6 GAK63440.1 - 1.7e-08 34.0 0.3 0.18 11.0 0.2 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) Rap1-DNA-bind PF09197.10 GAK63440.1 - 0.15 12.7 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 Rap1, DNA-binding IML1 PF12257.8 GAK63443.1 - 1.3e-114 382.1 0.1 2.7e-114 381.1 0.0 1.6 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 GAK63443.1 - 3.6e-18 65.4 0.2 7.7e-18 64.3 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2_3 PF14378.6 GAK63444.1 - 1.8e-20 73.5 17.1 1.8e-20 73.5 17.1 2.2 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 GAK63444.1 - 4.7e-07 29.6 10.8 4.7e-07 29.6 10.8 2.3 2 1 1 3 3 3 1 PAP2 superfamily DUF4449 PF14613.6 GAK63445.1 - 5.1e-06 26.7 0.1 5.1e-06 26.7 0.1 5.1 4 2 1 5 5 5 1 Protein of unknown function (DUF4449) ApoLp-III PF07464.11 GAK63445.1 - 0.0081 16.3 18.0 0.42 10.7 0.8 3.8 3 0 0 3 3 3 2 Apolipophorin-III precursor (apoLp-III) TetR_C_22 PF17928.1 GAK63445.1 - 0.019 15.3 1.7 4.2 7.7 0.1 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4420 PF14390.6 GAK63445.1 - 0.022 14.0 2.1 0.13 11.5 0.3 2.3 2 0 0 2 2 2 0 Putative PD-(D/E)XK family member, (DUF4420) Nexin_C PF08628.12 GAK63445.1 - 0.023 15.2 0.7 0.11 13.1 0.0 2.5 2 0 0 2 2 2 0 Sorting nexin C terminal Katanin_con80 PF13925.6 GAK63445.1 - 0.11 12.5 0.3 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 con80 domain of Katanin PhoU_div PF01865.16 GAK63445.1 - 0.16 11.3 2.9 0.41 9.9 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF47 AF0941-like PF14591.6 GAK63445.1 - 0.38 11.3 5.8 1.7 9.3 1.6 2.9 2 0 0 2 2 2 0 AF0941-like Syntaxin-6_N PF09177.11 GAK63445.1 - 0.7 10.5 11.5 5 7.8 2.7 4.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF883 PF05957.13 GAK63445.1 - 1.7 9.3 39.8 1.3 9.7 4.4 6.7 4 1 2 7 7 7 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 GAK63445.1 - 2.4 6.0 6.3 0.95 7.3 0.4 2.6 2 1 1 3 3 3 0 Prominin Nif11 PF07862.11 GAK63445.1 - 2.9 8.2 11.1 19 5.6 0.0 5.6 6 0 0 6 6 6 0 Nif11 domain DUF445 PF04286.12 GAK63445.1 - 3.8 7.2 13.7 4.7 6.9 9.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF445) Acetyltransf_1 PF00583.25 GAK63446.1 - 5.9e-14 52.3 0.1 8.2e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAK63446.1 - 2.4e-09 37.0 0.1 4.2e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAK63446.1 - 6.2e-09 35.9 0.1 9.8e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK63446.1 - 3e-08 34.0 0.1 4.3e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAK63446.1 - 6.8e-06 25.8 0.1 2.5e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAK63446.1 - 2.4e-05 24.4 0.1 3.7e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAK63446.1 - 0.0001 23.0 0.0 0.00012 22.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAK63446.1 - 0.0026 17.9 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 GAK63446.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_13 PF13880.6 GAK63446.1 - 0.16 12.0 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Aminotran_1_2 PF00155.21 GAK63448.1 - 4e-33 115.1 0.0 9.1e-33 113.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAK63448.1 - 0.0013 18.1 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase TPR_1 PF00515.28 GAK63449.1 - 1.3e-11 43.7 10.9 2.9e-05 23.7 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat RPAP3_C PF13877.6 GAK63449.1 - 1.2e-09 38.6 0.1 2.3e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 GAK63449.1 - 1.6e-07 30.9 14.0 0.0042 17.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAK63449.1 - 0.00012 21.7 2.3 1.6 8.5 0.0 3.3 3 0 0 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.6 GAK63449.1 - 0.00088 19.3 0.6 0.58 10.3 0.1 2.6 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 GAK63449.1 - 0.00099 19.7 2.1 0.00099 19.7 2.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAK63449.1 - 0.0012 19.3 12.0 0.34 11.4 0.7 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAK63449.1 - 0.0016 18.5 1.2 0.0042 17.2 1.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAK63449.1 - 0.0086 16.2 2.9 5.3 7.5 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAK63449.1 - 0.011 16.0 0.7 0.059 13.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAK63449.1 - 0.21 11.9 5.4 1.9 8.9 0.9 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK63449.1 - 0.72 10.8 10.1 1 10.3 2.0 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF1682 PF07946.14 GAK63450.1 - 0.0025 17.1 1.3 0.0028 16.9 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) FAM176 PF14851.6 GAK63450.1 - 1 9.0 7.9 0.89 9.2 0.1 2.1 2 0 0 2 2 2 0 FAM176 family Brix PF04427.18 GAK63453.1 - 2.3e-28 99.6 0.3 3.4e-28 99.1 0.3 1.2 1 0 0 1 1 1 1 Brix domain Ribosomal_L28 PF00830.19 GAK63454.1 - 2.6e-19 69.2 0.2 6.6e-19 67.9 0.2 1.7 1 0 0 1 1 1 1 Ribosomal L28 family PIN_4 PF13638.6 GAK63455.1 - 0.00045 20.5 0.0 0.00089 19.6 0.0 1.4 1 0 0 1 1 1 1 PIN domain Sec23_trunk PF04811.15 GAK63456.1 - 3.4e-77 259.3 0.0 4.7e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAK63456.1 - 5.5e-31 107.2 0.0 9.8e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GAK63456.1 - 4.4e-26 90.7 0.1 9.3e-26 89.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GAK63456.1 - 6.8e-16 58.0 6.2 1.4e-15 57.1 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAK63456.1 - 7.8e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAK63456.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DnaJ PF00226.31 GAK63457.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 GAK63457.1 - 0.00012 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Pam16 Glyco_transf_41 PF13844.6 GAK63458.1 - 1.1e-105 353.8 0.3 2e-49 168.3 0.0 4.1 3 1 1 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.28 GAK63458.1 - 3.2e-20 71.0 0.0 3.4e-05 23.5 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAK63458.1 - 6.4e-18 63.8 3.1 0.0006 20.0 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAK63458.1 - 3.6e-17 61.8 5.2 1.6e-05 24.5 0.0 6.4 3 2 3 6 6 6 4 TPR repeat TPR_2 PF07719.17 GAK63458.1 - 3.7e-16 57.9 0.4 0.0016 18.4 0.0 6.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAK63458.1 - 1.1e-14 53.3 0.0 1.4e-05 24.9 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAK63458.1 - 1.1e-14 53.7 7.2 0.00014 21.6 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAK63458.1 - 6.5e-10 39.0 3.6 0.11 13.4 0.0 6.7 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAK63458.1 - 6.8e-10 39.3 0.2 0.0014 19.0 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAK63458.1 - 1.9e-09 37.7 1.7 0.035 14.4 0.0 5.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAK63458.1 - 2.9e-09 36.3 0.0 0.018 15.0 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAK63458.1 - 0.0013 18.9 0.5 0.49 10.6 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAK63458.1 - 0.0027 18.3 22.1 0.47 11.1 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat WD40 PF00400.32 GAK63459.1 - 5e-08 33.5 6.1 0.61 11.0 0.0 6.3 7 1 0 7 7 7 3 WD domain, G-beta repeat Citrate_synt PF00285.21 GAK63460.1 - 9.9e-95 317.6 0.0 1.3e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Use1 PF09753.9 GAK63461.1 - 0.026 14.3 0.0 0.062 13.0 0.0 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF4316 PF14195.6 GAK63461.1 - 0.04 13.7 0.1 0.071 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DPBB_1 PF03330.18 GAK63462.1 - 7.9e-06 26.1 0.1 1.4e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAK63462.1 - 0.002 17.9 0.4 0.0039 17.0 0.4 1.4 1 0 0 1 1 1 1 Barwin family TIM21 PF08294.11 GAK63463.1 - 4.9e-14 52.4 0.0 1.2e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 TIM21 Transposase_23 PF03017.14 GAK63463.1 - 0.028 14.4 0.1 0.075 13.0 0.1 1.7 1 0 0 1 1 1 0 TNP1/EN/SPM transposase PAC1 PF16094.5 GAK63463.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 OapA PF04225.12 GAK63463.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain Yippee-Mis18 PF03226.14 GAK63464.1 - 2.7e-16 59.7 0.2 3.2e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 GAK63464.1 - 0.004 17.4 0.3 0.0056 16.9 0.3 1.3 1 1 0 1 1 1 1 C-terminal domain of RIG-I Endonuclease_7 PF02945.15 GAK63464.1 - 0.097 12.6 2.2 0.47 10.4 2.2 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII DUF4746 PF15928.5 GAK63466.1 - 0.059 12.8 0.2 6.6 6.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) NUSAP PF16006.5 GAK63466.1 - 0.14 11.9 0.7 0.25 11.1 0.7 1.4 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein PBP1_TM PF14812.6 GAK63466.1 - 0.37 11.2 3.1 0.61 10.5 3.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Str_synth PF03088.16 GAK63467.1 - 0.022 14.9 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Strictosidine synthase Arylesterase PF01731.20 GAK63467.1 - 0.082 13.1 0.0 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Arylesterase DUF3678 PF12435.8 GAK63467.1 - 0.28 10.6 5.5 7.9 5.9 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Ribosomal_L19e PF01280.20 GAK63468.1 - 4.3e-61 205.2 9.5 4.3e-61 205.2 9.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e Ribosomal_S27e PF01667.17 GAK63470.1 - 4.3e-27 93.6 4.6 6.5e-27 93.0 4.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 GAK63470.1 - 0.066 12.7 0.4 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Mu-like_Com PF10122.9 GAK63470.1 - 0.11 12.0 2.6 1 8.8 0.1 2.5 2 1 1 3 3 3 0 Mu-like prophage protein Com DHHC PF01529.20 GAK63471.1 - 2.3e-35 121.6 13.7 2.3e-35 121.6 13.7 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase QueC PF06508.13 GAK63471.1 - 1.5 8.2 3.8 2.4 7.6 3.8 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Synaptobrevin PF00957.21 GAK63472.1 - 3.4e-14 52.4 0.7 6.4e-14 51.5 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAK63472.1 - 2.4e-12 46.7 0.0 4.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 GAK63472.1 - 0.12 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region CENP-L PF13092.6 GAK63473.1 - 3.4e-09 37.1 0.0 1.2e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Glucan_synthase PF02364.15 GAK63474.1 - 0 1306.8 0.0 0 1306.2 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GAK63474.1 - 9.8e-41 139.1 0.1 2.7e-40 137.7 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 GAK63477.1 - 1.1e-94 317.3 0.0 1.5e-94 316.8 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 GAK63477.1 - 3.7e-18 66.0 1.0 8.2e-18 64.9 1.0 1.6 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 GAK63477.1 - 8.9e-05 22.0 0.0 0.00035 20.1 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rhomboid PF01694.22 GAK63479.1 - 7.6e-30 103.9 12.0 7.6e-30 103.9 12.0 1.6 2 0 0 2 2 2 1 Rhomboid family DUF4203 PF13886.6 GAK63479.1 - 0.003 17.3 7.3 0.003 17.3 7.3 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4203) Intg_mem_TP0381 PF09529.10 GAK63479.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.9 3 0 0 3 3 3 0 Integral membrane protein (intg_mem_TP0381) DUF2537 PF10801.8 GAK63479.1 - 9.2 6.6 10.9 0.35 11.1 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Iwr1 PF08574.10 GAK63480.1 - 6.8e-07 30.2 8.0 1.2e-06 29.4 5.7 3.6 3 0 0 3 3 3 2 Transcription factor Iwr1 Ras PF00071.22 GAK63481.1 - 1.3e-54 184.1 0.0 1.5e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK63481.1 - 1.7e-20 73.5 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK63481.1 - 2.4e-07 30.4 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAK63481.1 - 0.00043 19.9 0.2 0.0029 17.2 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAK63481.1 - 0.0016 18.4 0.2 0.52 10.2 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAK63481.1 - 0.0076 15.6 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAK63481.1 - 0.013 15.0 0.1 0.083 12.4 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B CbiA PF01656.23 GAK63481.1 - 0.022 14.8 0.3 0.11 12.6 0.3 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 GAK63481.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GAK63481.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-C2H2_6 PF13912.6 GAK63482.1 - 0.002 18.0 0.9 0.002 18.0 0.9 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAK63482.1 - 0.0052 17.1 2.9 0.01 16.1 2.9 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2 PF00096.26 GAK63482.1 - 0.016 15.6 1.8 0.016 15.6 1.8 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK63482.1 - 0.047 14.1 0.7 0.047 14.1 0.7 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAK63482.1 - 0.48 11.4 13.5 0.15 13.0 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Gly-zipper_YMGG PF13441.6 GAK63482.1 - 0.67 9.8 10.5 0.15 11.8 5.3 2.1 2 0 0 2 2 2 0 YMGG-like Gly-zipper MccV PF17508.2 GAK63482.1 - 1.4 9.5 5.2 34 5.1 2.6 3.3 2 1 1 3 3 3 0 Microcin V bacteriocin Vta1 PF04652.16 GAK63483.1 - 3.5e-52 176.2 2.2 4.7e-52 175.8 2.2 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 GAK63483.1 - 1.3e-12 47.2 0.3 1.3e-12 47.2 0.3 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain MCM PF00493.23 GAK63484.1 - 9.1e-99 329.1 0.0 1.3e-98 328.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAK63484.1 - 7.9e-38 129.2 0.8 1.3e-37 128.4 0.8 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAK63484.1 - 1.7e-26 92.4 2.5 3.9e-26 91.3 2.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAK63484.1 - 4.7e-17 62.5 0.0 1.3e-16 61.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 GAK63484.1 - 4.9e-08 33.1 0.0 2e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAK63484.1 - 4.6e-07 29.4 0.1 0.00025 20.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAK63484.1 - 0.00028 20.8 0.1 0.021 14.7 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAK63484.1 - 0.0064 16.2 0.2 1.1 9.0 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_lid_2 PF17863.1 GAK63484.1 - 0.053 13.4 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 GAK63484.1 - 0.11 12.9 0.0 0.11 12.9 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain WD40 PF00400.32 GAK63485.1 - 7.8e-18 64.5 5.9 6.5e-05 23.6 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK63485.1 - 2.5e-15 56.5 3.2 0.00014 22.1 0.1 5.1 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK63485.1 - 3e-06 26.5 0.0 0.00037 19.5 0.0 3.1 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAK63485.1 - 7.9e-06 25.9 0.1 0.0016 18.4 0.0 2.9 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAK63485.1 - 0.0013 18.1 0.2 0.0077 15.6 0.1 2.1 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 GAK63485.1 - 0.022 12.8 0.2 3.1 5.7 0.1 2.5 2 1 1 3 3 3 0 IKI3 family DUF3512 PF12024.8 GAK63486.1 - 2.6e-05 23.8 0.1 5.4e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) zf-CCCH PF00642.24 GAK63487.1 - 1.6e-14 53.3 15.4 5e-09 35.8 2.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK63487.1 - 2.7e-06 27.2 4.7 2.7e-06 27.2 4.7 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAK63487.1 - 0.00044 20.0 2.0 0.00044 20.0 2.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger oligo_HPY PF08352.12 GAK63487.1 - 0.15 12.6 5.9 2.5 8.7 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Defensin_int PF17858.1 GAK63487.1 - 0.49 10.4 4.3 0.78 9.8 1.5 2.4 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide zf-CCCH_3 PF15663.5 GAK63487.1 - 4.2 7.6 9.0 16 5.8 2.0 2.3 1 1 1 2 2 2 0 Zinc-finger containing family DUF2418 PF10332.9 GAK63488.1 - 1.2e-22 80.3 0.7 2e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Cation_ATPase_C PF00689.21 GAK63488.1 - 0.036 13.8 0.6 0.058 13.1 0.6 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Ras PF00071.22 GAK63490.1 - 7.1e-62 207.8 0.1 8.4e-62 207.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK63490.1 - 8.3e-34 116.4 0.1 1.3e-33 115.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK63490.1 - 2.1e-12 46.9 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK63490.1 - 5.2e-06 26.5 0.0 8.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK63490.1 - 0.00017 21.2 0.1 0.001 18.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAK63490.1 - 0.0014 18.5 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAK63490.1 - 0.0034 17.7 0.1 0.041 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 GAK63490.1 - 0.0034 16.9 0.0 0.0068 15.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAK63490.1 - 0.0061 17.0 0.1 0.01 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 GAK63490.1 - 0.011 15.1 0.1 0.023 14.0 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 GAK63490.1 - 0.018 14.8 0.0 0.067 12.9 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 GAK63490.1 - 0.034 14.7 0.2 0.044 14.3 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 GAK63490.1 - 0.037 13.5 0.1 0.085 12.4 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 GAK63490.1 - 0.048 13.9 0.2 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAK63490.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAK63490.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 GAK63490.1 - 0.076 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 GAK63490.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 GAK63490.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AEP1 PF17049.5 GAK63490.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Xpo1 PF08389.12 GAK63491.1 - 1e-22 80.8 0.0 2.4e-21 76.4 0.0 3.2 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 GAK63491.1 - 7.6e-06 25.8 0.3 2.1e-05 24.3 0.3 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain AAA PF00004.29 GAK63492.1 - 4.4e-41 140.4 0.0 8.1e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAK63492.1 - 1.7e-29 101.6 0.4 7.3e-29 99.5 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 GAK63492.1 - 2.3e-24 85.2 7.8 6.4e-24 83.8 7.8 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 GAK63492.1 - 1e-08 34.8 0.0 2.4e-07 30.5 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 GAK63492.1 - 2.8e-05 24.6 0.8 0.0032 17.9 0.1 3.3 3 1 1 4 4 4 1 AAA ATPase domain TIP49 PF06068.13 GAK63492.1 - 6.7e-05 22.2 0.4 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 GAK63492.1 - 8.4e-05 22.9 0.1 0.018 15.4 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 GAK63492.1 - 9.9e-05 22.6 0.6 0.028 14.7 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAK63492.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAK63492.1 - 0.00021 21.1 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 GAK63492.1 - 0.00027 21.0 0.0 0.00085 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAK63492.1 - 0.00035 20.8 0.1 0.0011 19.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 GAK63492.1 - 0.0011 19.0 0.3 0.0044 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAK63492.1 - 0.0019 18.3 0.0 0.0081 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAK63492.1 - 0.002 17.4 0.0 0.0044 16.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 GAK63492.1 - 0.0089 16.5 0.1 0.032 14.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 GAK63492.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GAK63492.1 - 0.014 15.0 0.1 0.78 9.3 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAK63492.1 - 0.016 15.7 0.3 0.062 13.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAK63492.1 - 0.017 14.8 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAK63492.1 - 0.021 14.2 0.0 5.6 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC AFG1_ATPase PF03969.16 GAK63492.1 - 0.068 12.0 0.1 1.6 7.5 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.26 GAK63492.1 - 0.083 12.6 0.0 0.5 10.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 GAK63492.1 - 0.099 12.6 0.1 0.78 9.6 0.0 2.4 2 1 1 3 3 3 0 NACHT domain PhoH PF02562.16 GAK63492.1 - 0.12 11.8 0.1 0.3 10.5 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 GAK63492.1 - 0.17 12.0 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4407 PF14362.6 GAK63492.1 - 3 7.1 5.2 1.1 8.5 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Vps39_2 PF10367.9 GAK63493.1 - 2.2e-10 40.9 0.1 7.4e-10 39.2 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 GAK63493.1 - 0.00023 21.4 0.1 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 GAK63493.1 - 0.0059 16.3 0.0 0.026 14.1 0.0 2.0 2 1 0 2 2 2 1 CNH domain zf-C2H2 PF00096.26 GAK63494.1 - 1.3e-05 25.4 12.6 0.0027 18.1 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK63494.1 - 5.3e-05 23.7 12.4 0.01 16.6 1.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAK63494.1 - 0.0013 18.6 2.2 0.0016 18.4 0.5 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK63494.1 - 0.085 13.3 10.8 2.2 8.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAK63494.1 - 0.31 11.4 10.7 0.34 11.2 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.27 GAK63495.1 - 6.7e-57 189.4 2.1 2.8e-20 72.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CLN3 PF02487.17 GAK63497.1 - 0.0079 15.3 0.1 0.015 14.4 0.1 1.6 1 1 0 1 1 1 1 CLN3 protein Phage_coat PF09063.10 GAK63497.1 - 0.046 13.7 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage PP7 coat protein Osw5 PF17062.5 GAK63497.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Outer spore wall 5 Presenilin PF01080.17 GAK63497.1 - 1.9 7.2 4.6 2.7 6.6 4.6 1.3 1 0 0 1 1 1 0 Presenilin Inositol_P PF00459.25 GAK63498.1 - 8.9e-53 179.5 0.2 1.1e-51 175.9 0.2 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family LIM PF00412.22 GAK63499.1 - 6.9e-16 58.2 28.1 1.5e-10 41.2 2.2 4.2 4 0 0 4 4 4 3 LIM domain WRC PF08879.10 GAK63499.1 - 0.0021 17.7 0.5 3.1 7.6 0.0 2.9 2 0 0 2 2 2 2 WRC Phage_sheath_1 PF04984.14 GAK63499.1 - 5.2 6.9 7.7 0.36 10.7 1.7 2.0 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Pkinase PF00069.25 GAK63500.1 - 1.8e-66 224.2 0.0 2.4e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63500.1 - 3.9e-46 157.4 0.0 5.7e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK63500.1 - 7.2e-08 32.1 0.0 2.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAK63500.1 - 0.012 15.6 0.1 0.21 11.5 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ras_bdg_2 PF14847.6 GAK63500.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Kdo PF06293.14 GAK63500.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAK63500.1 - 0.094 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain KilA-N PF04383.13 GAK63502.1 - 0.0009 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 KilA-N domain RXT2_N PF08595.11 GAK63503.1 - 0.0036 17.4 0.5 0.0036 17.4 0.5 4.3 2 1 0 2 2 2 1 RXT2-like, N-terminal PCI PF01399.27 GAK63505.1 - 1.6e-05 25.3 0.0 3.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain Sugar_tr PF00083.24 GAK63508.1 - 1.7e-101 340.3 23.2 2.1e-101 340.0 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK63508.1 - 6.8e-16 58.1 53.2 3.9e-15 55.6 28.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LIP PF03583.14 GAK63510.1 - 2.2e-65 220.8 0.1 2.9e-65 220.4 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_8 PF06259.12 GAK63510.1 - 0.013 15.2 0.4 3.8 7.1 0.0 3.1 3 0 0 3 3 3 0 Alpha/beta hydrolase Peptidase_S9 PF00326.21 GAK63510.1 - 0.17 11.4 1.8 2.4 7.6 0.2 2.9 2 1 0 2 2 2 0 Prolyl oligopeptidase family UPF0730 PF15827.5 GAK63510.1 - 0.48 10.2 3.4 0.56 10.0 0.1 2.7 4 0 0 4 4 4 0 UPF0730 unknown protein family DUF5427 PF10310.9 GAK63511.1 - 2.5e-45 155.3 12.0 3.7e-43 148.2 7.6 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5427) Pup PF05639.11 GAK63511.1 - 0.86 10.6 0.1 0.86 10.6 0.1 3.8 2 1 1 4 4 4 0 Pup-like protein Sugar_tr PF00083.24 GAK63512.1 - 5.7e-59 200.2 14.7 3.9e-58 197.4 14.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK63512.1 - 3.4e-14 52.5 34.9 3.4e-14 52.5 34.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BLM10_mid PF16507.5 GAK63513.1 - 7.2e-175 582.6 0.0 1.3e-174 581.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GAK63513.1 - 1.7e-25 88.8 0.5 7.6e-24 83.4 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT PF02985.22 GAK63513.1 - 0.00046 20.2 0.1 0.005 17.0 0.1 3.0 1 0 0 1 1 1 1 HEAT repeat HEAT_EZ PF13513.6 GAK63513.1 - 0.0029 18.1 0.1 0.013 16.0 0.1 2.1 1 0 0 1 1 1 1 HEAT-like repeat Arm PF00514.23 GAK63513.1 - 0.003 17.5 0.1 0.014 15.4 0.1 2.3 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat BLM10_N PF16547.5 GAK63513.1 - 0.0032 17.7 0.1 0.0098 16.2 0.1 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT_2 PF13646.6 GAK63513.1 - 0.0045 17.3 1.6 0.02 15.2 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats TAF6_C PF07571.13 GAK63513.1 - 0.011 16.0 0.4 0.28 11.5 0.0 2.8 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 GAK63513.1 - 0.1 13.2 0.1 0.58 10.8 0.1 2.3 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cut8 PF08559.10 GAK63514.1 - 3.5e-15 56.3 0.1 7.6e-14 51.9 0.0 2.6 3 0 0 3 3 3 1 Cut8, nuclear proteasome tether protein PEP-utilisers_N PF05524.13 GAK63514.1 - 0.041 14.0 0.3 0.12 12.5 0.3 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Pkinase PF00069.25 GAK63516.1 - 1.6e-74 250.6 0.0 1.8e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63516.1 - 2.6e-35 122.0 0.0 3.3e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAK63516.1 - 0.00026 20.1 0.0 0.0024 16.9 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAK63516.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GAK63516.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 GAK63516.1 - 0.077 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Utp12 PF04003.12 GAK63517.1 - 5.3e-24 84.6 0.4 9.5e-24 83.8 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 GAK63517.1 - 0.0006 20.6 3.9 0.011 16.5 0.1 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat CoA_binding PF02629.19 GAK63518.1 - 3.5e-28 98.1 0.1 7.9e-28 97.0 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 GAK63518.1 - 4.9e-19 68.7 0.0 3.2e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 GAK63518.1 - 2.8e-06 27.2 0.0 8.9e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAK63518.1 - 0.00017 22.1 0.0 0.00045 20.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain HNH_3 PF13392.6 GAK63519.1 - 0.00033 20.3 0.5 0.00033 20.3 0.5 1.7 2 0 0 2 2 2 1 HNH endonuclease SRP-alpha_N PF04086.13 GAK63520.1 - 4.2 7.2 6.4 5.7 6.8 6.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MMR_HSR1_Xtn PF16897.5 GAK63521.1 - 2.4e-38 130.4 1.4 4.7e-38 129.5 1.4 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAK63521.1 - 7.9e-19 67.8 0.0 1.6e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 GAK63521.1 - 1.8e-15 56.7 0.0 4.1e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain TAP_C PF03943.13 GAK63521.1 - 2.7e-15 55.7 0.8 2.7e-15 55.7 0.8 1.8 2 0 0 2 2 1 1 TAP C-terminal domain FeoB_N PF02421.18 GAK63521.1 - 9.1e-11 41.5 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B LRR_9 PF14580.6 GAK63521.1 - 7.2e-06 25.6 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GAK63521.1 - 0.0064 16.9 5.1 0.0082 16.5 1.3 2.7 2 1 1 3 3 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAK63521.1 - 0.023 14.5 3.0 0.48 10.2 3.6 2.8 2 1 0 2 2 2 0 Leucine rich repeat Dynamin_N PF00350.23 GAK63521.1 - 0.081 13.0 0.4 4.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Dynamin family NTF2 PF02136.20 GAK63521.1 - 0.099 13.2 0.1 0.94 10.1 0.1 2.3 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain ATF7IP_BD PF16788.5 GAK63521.1 - 0.16 12.1 0.3 0.33 11.0 0.3 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain AIG1 PF04548.16 GAK63521.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family CBS PF00571.28 GAK63522.1 - 1.3e-27 96.0 8.6 7.1e-07 29.6 0.3 5.7 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 GAK63522.1 - 9.3e-07 28.7 0.1 2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DUF4288 PF14119.6 GAK63522.1 - 0.096 13.1 2.0 31 5.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) DUF2380 PF09533.10 GAK63522.1 - 0.35 10.5 6.4 2.6 7.6 0.0 3.1 3 0 0 3 3 3 0 Predicted lipoprotein of unknown function (DUF2380) Zn_clus PF00172.18 GAK63523.1 - 4.1e-06 26.8 12.0 7.5e-06 26.0 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK63523.1 - 0.004 16.2 0.2 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Talin_middle PF09141.10 GAK63524.1 - 0.03 14.4 2.2 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 Talin, middle domain Abhydro_lipase PF04083.16 GAK63524.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region BCAS2 PF05700.11 GAK63525.1 - 5.7e-67 225.4 2.0 7e-67 225.1 2.0 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Erythro-docking PF09277.11 GAK63525.1 - 0.0021 17.9 1.1 0.59 10.1 0.4 2.5 2 0 0 2 2 2 2 Erythronolide synthase, docking Mesd PF10185.9 GAK63525.1 - 0.023 14.7 0.2 0.037 14.0 0.2 1.3 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor DUF5320 PF17253.2 GAK63525.1 - 0.023 15.8 3.7 0.76 10.9 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Nup54 PF13874.6 GAK63525.1 - 0.057 13.5 12.4 0.074 13.2 10.6 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Enkurin PF13864.6 GAK63525.1 - 0.06 13.8 7.7 0.13 12.7 7.7 1.6 1 0 0 1 1 1 0 Calmodulin-binding DUF3027 PF11228.8 GAK63525.1 - 0.075 13.0 1.2 0.2 11.7 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3027) Swi5 PF07061.11 GAK63525.1 - 0.89 9.7 5.7 25 5.1 0.8 3.2 3 0 0 3 3 3 0 Swi5 JIP_LZII PF16471.5 GAK63525.1 - 1.1 9.5 8.5 1 9.6 1.2 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II NPV_P10 PF05531.12 GAK63525.1 - 1.4 9.5 6.2 7.4 7.1 1.3 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 GAK63525.1 - 3.3 8.0 14.5 5.3 7.4 1.1 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain GIT_CC PF16559.5 GAK63525.1 - 3.5 7.6 10.9 6.3 6.8 1.5 2.7 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 GAK63525.1 - 8.8 6.2 9.5 7 6.5 2.4 2.4 2 0 0 2 2 2 0 Septum formation initiator Complex1_30kDa PF00329.19 GAK63526.1 - 1.3e-46 158.2 0.1 1.7e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Arm PF00514.23 GAK63527.1 - 0.00015 21.7 29.8 0.001 19.0 0.2 8.8 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAK63527.1 - 0.0015 19.0 21.2 0.015 15.8 0.1 7.9 8 0 0 8 8 8 2 HEAT-like repeat HEAT PF02985.22 GAK63527.1 - 0.05 13.9 22.6 0.16 12.3 0.1 7.8 8 0 0 8 8 8 0 HEAT repeat MCM PF00493.23 GAK63528.1 - 6.7e-98 326.3 0.1 9.8e-98 325.7 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAK63528.1 - 5.8e-34 116.7 0.0 9.6e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAK63528.1 - 4.4e-23 81.5 0.5 1.1e-22 80.3 0.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAK63528.1 - 7.2e-13 49.0 0.2 2.8e-12 47.1 0.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAK63528.1 - 8.4e-08 31.9 0.0 1.1e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAK63528.1 - 0.0037 17.1 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAK63528.1 - 0.0092 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 GAK63528.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BUD22 PF09073.10 GAK63528.1 - 0.28 10.5 6.3 0.42 9.9 6.3 1.2 1 0 0 1 1 1 0 BUD22 Ysc84 PF04366.12 GAK63529.1 - 1.2e-38 131.7 0.5 2.7e-38 130.6 0.5 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 GAK63529.1 - 5.6e-12 45.1 0.1 1.1e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAK63529.1 - 8.1e-10 38.2 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAK63529.1 - 4.6e-09 36.0 0.0 8.5e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF5374 PF17344.2 GAK63531.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5374) UvrD-helicase PF00580.21 GAK63532.1 - 1.1e-69 235.4 0.1 1.1e-69 235.4 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 GAK63532.1 - 1.6e-58 198.8 0.0 1.1e-30 107.2 0.0 2.8 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GAK63532.1 - 4.4e-29 101.7 0.0 9e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 GAK63532.1 - 8.7e-12 44.7 0.0 2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 GAK63532.1 - 5.6e-06 26.2 0.4 0.047 13.4 0.8 2.5 2 0 0 2 2 2 2 AAA domain HNH_3 PF13392.6 GAK63532.1 - 9.6e-06 25.3 0.2 2.5e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 HNH endonuclease AAA_22 PF13401.6 GAK63532.1 - 0.17 12.1 0.1 14 5.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain PALP PF00291.25 GAK63533.1 - 3.3e-51 174.4 4.3 4.1e-51 174.1 4.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU PF00009.27 GAK63534.1 - 9.7e-52 175.3 0.0 1.7e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 GAK63534.1 - 1.4e-21 76.4 0.0 3.1e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAK63534.1 - 1e-15 57.5 0.2 1.9e-08 34.2 0.0 2.5 1 1 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAK63534.1 - 1.6e-08 34.8 0.0 5e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAK63534.1 - 9.2e-05 22.3 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAK63534.1 - 0.0049 16.9 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 GAK63534.1 - 0.017 15.6 0.0 1.4 9.5 0.0 2.9 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain EFG_IV PF03764.18 GAK63534.1 - 0.046 13.5 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Elongation factor G, domain IV cobW PF02492.19 GAK63534.1 - 0.14 11.8 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HCO3_cotransp PF00955.21 GAK63535.1 - 8e-58 196.5 9.3 6.6e-28 97.8 1.1 3.1 1 1 1 2 2 2 2 HCO3- transporter family FHA PF00498.26 GAK63536.1 - 0.024 15.0 0.0 0.07 13.5 0.0 1.8 1 0 0 1 1 1 0 FHA domain NOA36 PF06524.12 GAK63536.1 - 0.15 11.4 4.5 0.26 10.6 4.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3246 PF11596.8 GAK63536.1 - 4.1 6.8 12.0 0.16 11.4 5.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Nop14 PF04147.12 GAK63536.1 - 5.5 5.1 7.4 9.2 4.3 7.4 1.3 1 0 0 1 1 1 0 Nop14-like family OCRE PF17780.1 GAK63537.1 - 4.1e-05 23.5 2.9 0.097 12.7 0.0 4.0 4 0 0 4 4 4 2 OCRE domain DAO_C PF16901.5 GAK63537.1 - 0.025 14.4 0.3 0.058 13.3 0.3 1.5 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase EcKinase PF02958.20 GAK63537.1 - 0.14 11.4 1.9 0.32 10.2 1.9 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase RAP1 PF07218.11 GAK63537.1 - 0.21 9.9 2.6 0.34 9.1 2.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3106 PF11304.8 GAK63537.1 - 8.2 7.0 15.6 0.15 12.5 2.6 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3106) AMP-binding PF00501.28 GAK63538.1 - 7.3e-71 239.0 0.0 9.6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAK63538.1 - 7.3e-66 222.0 0.0 1.1e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAK63538.1 - 5.9e-13 49.0 0.0 1.6e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 GAK63538.1 - 2.5e-11 42.9 0.1 9.5e-06 24.5 0.1 3.8 2 1 0 2 2 2 2 Condensation domain AMP-binding_C PF13193.6 GAK63538.1 - 8.8e-05 23.4 0.3 0.0024 18.8 0.3 3.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 GAK63538.1 - 0.0017 17.9 0.1 0.0044 16.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK63538.1 - 0.0022 17.0 0.0 0.043 12.8 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1688 PF07958.11 GAK63541.1 - 2.5e-171 570.1 0.0 2.8e-171 569.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 GAK63541.1 - 0.0021 17.7 0.0 0.03 13.9 0.0 2.0 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family ABC2_membrane PF01061.24 GAK63542.1 - 3.7e-36 124.5 16.2 3.7e-36 124.5 16.2 2.3 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 GAK63542.1 - 6.9e-24 84.9 0.0 1.1e-23 84.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAK63542.1 - 0.00018 20.8 19.4 0.00018 20.7 18.0 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAK63542.1 - 0.00084 19.2 0.0 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAK63542.1 - 0.013 15.3 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 GAK63542.1 - 0.032 14.5 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAK63542.1 - 0.046 13.3 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAK63542.1 - 0.094 12.6 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 GAK63542.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAK63542.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 GAK63542.1 - 0.2 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAK63542.1 - 0.26 11.8 0.0 0.44 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gate PF07670.14 GAK63542.1 - 0.69 10.2 4.8 13 6.1 0.5 2.8 2 1 0 2 2 2 0 Nucleoside recognition Hemerythrin PF01814.23 GAK63544.1 - 1.7e-14 54.5 1.2 1.9e-10 41.4 0.1 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LRR_4 PF12799.7 GAK63545.1 - 6.9e-25 86.7 11.9 0.00018 21.8 0.6 9.0 7 3 3 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAK63545.1 - 1.1e-22 79.5 14.0 2.2e-08 33.7 0.6 5.9 6 0 0 6 6 6 3 Leucine rich repeat LRR_9 PF14580.6 GAK63545.1 - 9.1e-10 38.3 4.2 0.0041 16.7 0.2 4.0 2 1 2 4 4 4 3 Leucine-rich repeat Nop PF01798.18 GAK63545.1 - 0.12 11.9 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin LRR_6 PF13516.6 GAK63545.1 - 0.22 11.7 14.9 0.41 10.8 0.2 6.0 6 1 1 7 7 7 0 Leucine Rich repeat Med9 PF07544.13 GAK63545.1 - 1.7 8.8 3.7 1.1 9.3 0.7 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LRR_1 PF00560.33 GAK63545.1 - 9.1 7.3 20.8 20 6.2 0.4 7.9 10 0 0 10 10 10 0 Leucine Rich Repeat MAP65_ASE1 PF03999.12 GAK63546.1 - 3e-64 217.8 0.0 3.6e-57 194.4 0.0 2.2 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.12 GAK63546.1 - 0.57 10.2 2.4 0.91 9.6 0.1 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.10 GAK63546.1 - 1.2 9.5 11.1 7.7 6.9 0.2 4.0 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF1192 PF06698.11 GAK63546.1 - 4 7.6 7.5 3.4 7.8 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) ATG16 PF08614.11 GAK63546.1 - 7.9 6.6 27.2 1.2 9.4 0.4 5.0 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) BCDHK_Adom3 PF10436.9 GAK63547.1 - 1.2e-43 148.8 0.1 1.6e-43 148.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAK63547.1 - 4.6e-09 36.8 0.0 9.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KCNQ2_u3 PF16642.5 GAK63547.1 - 3.1 8.8 9.7 0.21 12.6 4.3 1.8 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 PGP_phosphatase PF09419.10 GAK63548.1 - 6.7e-49 165.7 0.0 2.4e-44 150.9 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 GAK63548.1 - 0.057 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 HAD-hyrolase-like DUF2373 PF10180.9 GAK63549.1 - 5.2e-13 48.6 0.1 4.4e-08 32.8 0.2 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) TFIIF_alpha PF05793.12 GAK63549.1 - 0.41 9.2 37.0 0.2 10.2 16.6 2.3 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GAK63549.1 - 5 5.3 18.7 0.82 7.9 15.2 1.5 2 0 0 2 2 2 0 CDC45-like protein SURF2 PF05477.11 GAK63549.1 - 6.7 6.3 20.1 5.2 6.7 18.3 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Macoilin PF09726.9 GAK63549.1 - 7.3 5.0 9.3 8.6 4.8 9.3 1.2 1 0 0 1 1 1 0 Macoilin family BMC PF00936.19 GAK63552.1 - 0.23 11.5 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 BMC domain Lum_binding PF00677.17 GAK63553.1 - 3.1e-38 129.6 0.1 5.3e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 Lumazine binding domain Homoserine_dh PF00742.19 GAK63554.1 - 1.5e-48 165.0 0.0 2.1e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAK63554.1 - 1.3e-14 54.8 0.0 2.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain BUD22 PF09073.10 GAK63555.1 - 7.9e-95 318.7 36.6 7.9e-95 318.7 36.6 2.1 2 0 0 2 2 2 1 BUD22 Efg1 PF10153.9 GAK63555.1 - 5.9 7.3 12.5 0.63 10.4 3.4 2.8 3 0 0 3 3 3 0 rRNA-processing protein Efg1 GMC_oxred_N PF00732.19 GAK63556.1 - 6.1e-57 193.2 0.0 9.2e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK63556.1 - 2.7e-34 118.8 0.3 5.4e-34 117.8 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_M20 PF01546.28 GAK63556.1 - 1.9e-30 106.1 0.0 3.8e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAK63556.1 - 0.00019 21.3 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Lycopene_cycl PF05834.12 GAK63556.1 - 0.00062 18.9 1.0 0.00091 18.4 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Peptidase_M28 PF04389.17 GAK63556.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 NAD_binding_8 PF13450.6 GAK63556.1 - 0.005 17.0 0.9 0.017 15.3 0.9 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAK63556.1 - 0.0057 15.9 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAK63556.1 - 0.023 13.9 0.2 0.052 12.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK63556.1 - 0.031 13.9 2.6 0.028 14.0 0.8 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAK63556.1 - 0.25 10.6 0.9 0.87 8.8 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK63556.1 - 0.75 8.8 5.5 1.5 7.8 5.5 1.5 1 0 0 1 1 1 0 FAD binding domain DLH PF01738.18 GAK63557.1 - 1.6e-20 73.6 0.3 1.9e-20 73.4 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF5134 PF17197.4 GAK63558.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) FMO-like PF00743.19 GAK63559.1 - 1.7e-17 63.0 0.0 2.6e-15 55.9 0.1 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAK63559.1 - 7.1e-12 45.2 0.0 7.5e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK63559.1 - 3.3e-11 43.0 0.1 8.7e-11 41.6 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK63559.1 - 1.8e-08 34.5 0.0 1e-06 28.8 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAK63559.1 - 5.9e-07 29.0 0.1 6.9e-06 25.4 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GAK63559.1 - 1.8e-05 24.5 0.4 0.23 11.0 0.0 3.5 2 1 2 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAK63559.1 - 2.2e-05 23.8 0.0 6.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 GAK63559.1 - 4.1e-05 24.1 0.3 0.0068 16.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 GAK63559.1 - 0.016 13.7 0.1 0.092 11.3 0.1 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GST_C_5 PF16865.5 GAK63559.1 - 0.036 14.7 0.1 0.095 13.3 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_2 PF00890.24 GAK63559.1 - 0.04 13.0 0.1 0.17 10.9 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 GAK63559.1 - 0.091 12.1 0.0 3.2 7.0 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAK63559.1 - 0.096 11.7 0.1 21 4.0 0.0 3.0 3 1 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 GAK63559.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Amidohydro_1 PF01979.20 GAK63560.1 - 1.6e-17 63.8 0.0 1e-09 38.2 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 GAK63560.1 - 2.5e-12 47.1 0.4 9.6e-09 35.2 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF3605 PF12239.8 GAK63561.1 - 2.7e-29 102.5 0.0 6.6e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) BcrAD_BadFG PF01869.20 GAK63562.1 - 3.7e-09 36.5 0.0 2.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Glucosamine_iso PF01182.20 GAK63563.1 - 2.4e-22 79.9 0.0 3.6e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Zn_clus PF00172.18 GAK63564.1 - 1.6e-06 28.1 9.0 1.6e-06 28.1 9.0 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAIN PF16489.5 GAK63564.1 - 0.16 11.4 0.3 0.28 10.6 0.3 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain PGM_PMM_I PF02878.16 GAK63565.1 - 5e-35 120.2 0.0 8.1e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAK63565.1 - 9e-16 58.4 0.0 2.8e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAK63565.1 - 1.5e-12 47.7 0.0 3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GAK63565.1 - 1.6e-08 34.6 0.0 4.5e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Lipase_3 PF01764.25 GAK63566.1 - 1.9e-11 44.0 0.0 1.9e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) OprF PF05736.11 GAK63566.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 OprF membrane domain ATP-synt_E PF05680.12 GAK63566.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.4 3 0 0 3 3 3 0 ATP synthase E chain DUF1479 PF07350.12 GAK63567.1 - 6.3e-145 483.1 0.0 7.7e-145 482.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 GAK63567.1 - 0.028 14.7 0.4 9.8 6.4 0.2 2.7 2 1 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.22 GAK63568.1 - 2.6e-55 188.0 0.0 3.5e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APS_kinase PF01583.20 GAK63572.1 - 1.1e-69 233.4 0.0 1.3e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 GAK63572.1 - 1.7e-06 28.2 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAK63572.1 - 7.8e-05 23.2 0.0 0.00011 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAK63572.1 - 0.00028 20.4 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 GAK63572.1 - 0.0053 16.5 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GAK63572.1 - 0.012 15.0 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 GAK63572.1 - 0.034 14.5 0.1 0.045 14.1 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAK63572.1 - 0.039 14.5 0.0 0.067 13.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF463 PF04317.12 GAK63572.1 - 0.056 12.4 0.1 0.082 11.8 0.1 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 PRK PF00485.18 GAK63572.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family GlcNAc-1_reg PF18440.1 GAK63572.1 - 0.093 13.0 0.0 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain TctC PF03401.14 GAK63572.1 - 0.16 11.0 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor CPT PF07931.12 GAK63572.1 - 0.19 11.6 0.1 0.41 10.5 0.1 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MaoC_dehydrat_N PF13452.6 GAK63573.1 - 3.3e-09 37.0 0.0 2.8e-06 27.5 0.0 2.9 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 GAK63573.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain SelR PF01641.18 GAK63574.1 - 6.5e-50 168.3 0.3 8.5e-50 167.9 0.3 1.1 1 0 0 1 1 1 1 SelR domain WD40 PF00400.32 GAK63575.1 - 4e-12 46.5 12.0 0.0016 19.3 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK63575.1 - 1.8e-06 28.1 0.0 1.9 8.9 0.0 4.9 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAK63576.1 - 0.15 13.0 9.6 14 6.7 0.1 4.8 4 0 0 4 4 4 0 WD domain, G-beta repeat MBOAT_2 PF13813.6 GAK63577.1 - 5.9e-09 36.1 0.8 3.9e-07 30.2 0.8 2.5 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DEAD PF00270.29 GAK63578.1 - 9.5e-49 165.5 0.0 1.8e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK63578.1 - 2.6e-33 114.7 0.0 8.6e-30 103.3 0.1 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAK63578.1 - 3.1e-05 24.1 3.2 6.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAK63578.1 - 0.0013 18.1 0.0 0.0013 18.1 0.0 3.4 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 GAK63578.1 - 0.01 15.1 0.0 0.01 15.1 0.0 2.5 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase Zip PF02535.22 GAK63578.1 - 0.23 10.6 1.3 0.27 10.4 1.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIF_alpha PF05793.12 GAK63578.1 - 1.2 7.6 23.0 1.8 7.1 23.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NPR3 PF03666.13 GAK63578.1 - 8.9 5.0 12.0 13 4.5 12.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 adh_short PF00106.25 GAK63579.1 - 4.7e-20 71.9 0.0 9e-13 48.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK63579.1 - 6.8e-15 55.3 0.0 5.6e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK63579.1 - 0.00012 22.1 0.1 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAK63579.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding EF-hand_5 PF13202.6 GAK63580.1 - 0.04 13.4 0.3 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 EF hand Ras PF00071.22 GAK63581.1 - 2e-52 177.1 0.0 2.4e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK63581.1 - 1.8e-32 112.0 0.0 2.5e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK63581.1 - 3.5e-11 42.9 0.0 4.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAK63581.1 - 1.4e-05 24.7 0.0 0.00067 19.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAK63581.1 - 0.00012 21.5 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK63581.1 - 0.00024 21.2 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 GAK63581.1 - 0.0029 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DAP3 PF10236.9 GAK63581.1 - 0.0095 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 GAK63581.1 - 0.011 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 GAK63581.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 GAK63581.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 GAK63581.1 - 0.023 15.1 0.0 0.048 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 GAK63581.1 - 0.025 14.3 0.0 0.056 13.1 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 GAK63581.1 - 0.026 14.4 0.0 2.6 7.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 GAK63581.1 - 0.032 14.5 0.0 0.045 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 GAK63581.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2075 PF09848.9 GAK63581.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.18 GAK63581.1 - 0.23 10.7 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Septin RWD PF05773.22 GAK63582.1 - 3.6e-18 66.0 0.1 3.6e-18 66.0 0.1 1.9 2 1 0 2 2 2 1 RWD domain DFRP_C PF16543.5 GAK63582.1 - 8.7e-06 26.2 12.7 8.7e-06 26.2 12.7 3.1 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 DUF913 PF06025.12 GAK63582.1 - 0.21 10.5 3.7 0.29 10.1 3.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PRP1_N PF06424.12 GAK63582.1 - 6.9 7.1 21.6 2.8 8.4 18.8 1.8 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal HlyIII PF03006.20 GAK63583.1 - 1.4e-56 191.7 22.4 1.4e-56 191.7 22.4 2.5 2 1 0 2 2 2 1 Haemolysin-III related TMPIT PF07851.13 GAK63585.1 - 0.4 9.9 4.1 0.68 9.1 4.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein COMP PF11598.8 GAK63585.1 - 0.68 10.4 4.3 1.4 9.5 1.1 2.7 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Prominin PF05478.11 GAK63585.1 - 2.5 6.0 4.2 3.5 5.5 4.2 1.1 1 0 0 1 1 1 0 Prominin PhoPQ_related PF10142.9 GAK63588.1 - 0.073 11.7 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Cyt-b5 PF00173.28 GAK63589.1 - 1.7e-22 79.3 0.2 1.9e-22 79.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rit1_C PF17184.4 GAK63590.1 - 8.5e-95 317.3 0.0 1.1e-94 316.9 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 GAK63590.1 - 1.3e-23 83.4 0.0 3e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain HORMA PF02301.18 GAK63591.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 HORMA domain ABC_tran PF00005.27 GAK63592.1 - 4.3e-50 169.8 0.0 1e-29 103.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAK63592.1 - 7.1e-27 94.7 28.6 1.4e-14 54.4 7.9 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_22 PF13401.6 GAK63592.1 - 2.2e-05 24.7 0.8 0.13 12.5 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAK63592.1 - 2.4e-05 24.0 0.2 0.0066 16.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 GAK63592.1 - 4.1e-05 23.1 6.8 0.21 11.0 0.3 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK63592.1 - 5.6e-05 22.8 0.7 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK63592.1 - 0.00012 22.5 1.4 0.14 12.5 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAK63592.1 - 0.00017 21.5 1.1 0.063 13.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 GAK63592.1 - 0.00025 21.0 0.2 0.81 9.4 0.0 3.2 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system CbiA PF01656.23 GAK63592.1 - 0.0037 17.3 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 GAK63592.1 - 0.0072 16.4 0.0 6.2 6.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 GAK63592.1 - 0.021 14.4 3.3 1.7 8.2 0.6 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAK63592.1 - 0.021 14.5 0.9 10 5.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAK63592.1 - 0.024 15.2 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAK63592.1 - 0.027 14.4 3.0 0.63 9.9 0.3 3.2 4 0 0 4 4 4 0 NACHT domain AAA_7 PF12775.7 GAK63592.1 - 0.037 13.5 0.1 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 GAK63592.1 - 0.042 13.7 0.6 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 GAK63592.1 - 0.057 13.6 0.1 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAK63592.1 - 0.11 12.5 0.4 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 GAK63592.1 - 0.12 11.8 1.3 0.83 9.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Methyltr_RsmB-F PF01189.17 GAK63592.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MaoC_dehydratas PF01575.19 GAK63594.1 - 1e-27 96.2 0.0 4.8e-27 94.0 0.0 2.2 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAK63594.1 - 5.9e-10 39.4 0.0 2.8e-07 30.7 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase BAR PF03114.18 GAK63595.1 - 7.7e-44 150.1 6.6 1.1e-43 149.7 6.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAK63595.1 - 6.6e-15 54.5 0.1 1.3e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK63595.1 - 7.4e-14 51.4 0.1 1.7e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAK63595.1 - 1.3e-10 40.8 0.0 2.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 GAK63595.1 - 0.023 14.4 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Vac_Fusion PF02346.16 GAK63595.1 - 0.089 12.4 1.4 43 3.9 0.1 3.8 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Prefoldin PF02996.17 GAK63595.1 - 0.11 12.5 2.1 0.16 11.9 0.1 2.2 2 1 0 2 2 2 0 Prefoldin subunit Vps5 PF09325.10 GAK63595.1 - 0.72 9.4 6.0 1.9 8.0 0.0 2.8 2 1 1 3 3 3 0 Vps5 C terminal like COX16 PF14138.6 GAK63595.1 - 3.2 8.3 5.2 39 4.9 2.9 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Glyco_hydro_43 PF04616.14 GAK63597.1 - 4.9e-17 62.2 0.2 6.7e-17 61.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1295 PF06966.12 GAK63598.1 - 4.5e-52 176.9 0.5 5.9e-52 176.5 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GAK63598.1 - 0.0011 19.3 0.1 0.0047 17.3 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 GAK63598.1 - 0.0018 18.2 1.9 0.0033 17.4 0.0 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 GAK63598.1 - 0.018 15.4 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltransf_16 PF10294.9 GAK63599.1 - 5.8e-14 52.2 0.0 1e-11 44.9 0.0 2.3 1 1 0 1 1 1 1 Lysine methyltransferase SUZ PF12752.7 GAK63599.1 - 0.48 11.2 0.1 0.48 11.2 0.1 2.6 2 0 0 2 2 2 0 SUZ domain Metallopep PF12044.8 GAK63600.1 - 2.4e-94 316.4 0.0 5.8e-74 249.2 0.0 2.1 2 0 0 2 2 2 2 Putative peptidase family Peptidase_M66 PF10462.9 GAK63600.1 - 0.054 12.4 0.2 0.089 11.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Jacalin PF01419.17 GAK63600.1 - 0.07 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Aldo_ket_red PF00248.21 GAK63601.1 - 1.5e-49 168.8 0.1 5.1e-48 163.8 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Phage_X PF05155.15 GAK63601.1 - 0.083 13.3 0.0 0.65 10.4 0.0 2.4 3 0 0 3 3 3 0 Phage X family Sacchrp_dh_NADP PF03435.18 GAK63601.1 - 0.13 12.6 0.2 8.8 6.6 0.0 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DUF2256 PF10013.9 GAK63602.1 - 8.8e-14 51.3 3.4 1.4e-13 50.7 3.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.18 GAK63602.1 - 0.032 14.3 0.7 0.062 13.4 0.7 1.4 1 0 0 1 1 1 0 MYND finger zf-RING_12 PF17976.1 GAK63602.1 - 0.093 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aldose_epim PF01263.20 GAK63603.1 - 2.9e-29 102.3 0.0 5.1e-29 101.5 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase YjbT PF17089.5 GAK63604.1 - 0.1 12.6 0.3 0.26 11.3 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family Xan_ur_permease PF00860.20 GAK63605.1 - 7e-26 90.8 26.9 9e-25 87.2 26.9 2.2 1 1 0 1 1 1 1 Permease family ABC_tran PF00005.27 GAK63607.1 - 2.8e-50 170.4 0.8 5.1e-28 98.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAK63607.1 - 2.3e-32 112.7 18.5 1.8e-22 80.3 6.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAK63607.1 - 1.8e-09 37.4 6.1 0.0026 17.2 2.5 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK63607.1 - 1.6e-06 27.8 1.3 0.025 14.3 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAK63607.1 - 1.3e-05 25.5 0.4 0.16 12.2 0.3 3.4 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAK63607.1 - 1.6e-05 24.9 0.7 0.23 11.4 0.2 2.9 2 1 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 GAK63607.1 - 4.8e-05 23.3 1.0 1.9 8.2 0.1 4.3 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 GAK63607.1 - 0.00041 19.8 0.0 0.84 8.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 GAK63607.1 - 0.00052 20.1 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 GAK63607.1 - 0.0007 19.4 0.9 0.0098 15.6 0.2 2.9 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 GAK63607.1 - 0.0018 18.8 0.0 0.67 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAK63607.1 - 0.0024 18.3 3.2 0.18 12.1 0.2 3.3 3 1 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 GAK63607.1 - 0.0072 15.5 0.4 1.3 8.1 0.1 3.2 3 1 0 3 3 3 1 NB-ARC domain AAA_33 PF13671.6 GAK63607.1 - 0.04 14.1 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAK63607.1 - 0.049 13.4 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAK63607.1 - 0.057 13.0 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 GAK63607.1 - 0.075 12.3 0.0 8.6 5.5 0.0 2.6 3 0 0 3 3 3 0 Septin Pox_A32 PF04665.12 GAK63607.1 - 0.077 12.4 0.2 0.19 11.2 0.2 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_25 PF13481.6 GAK63607.1 - 0.08 12.5 0.8 7.1 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 GAK63607.1 - 0.084 12.6 0.0 9.4 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 GAK63607.1 - 0.16 12.0 0.7 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 GAK63607.1 - 0.16 11.3 0.2 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 GAK63607.1 - 0.28 11.2 0.6 0.6 10.2 0.2 1.7 2 0 0 2 2 1 0 Helicase HerA, central domain ABC_ATPase PF09818.9 GAK63607.1 - 4.5 6.0 7.8 0.48 9.2 0.0 2.7 4 0 0 4 4 4 0 Predicted ATPase of the ABC class MARVEL PF01284.23 GAK63608.1 - 5.7e-08 32.9 6.5 8.5e-08 32.3 6.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain MSP1a PF11670.8 GAK63608.1 - 0.23 10.7 0.3 0.36 10.1 0.3 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF2627 PF11118.8 GAK63608.1 - 8 7.1 8.5 1.7 9.2 0.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2627) Cmc1 PF08583.10 GAK63609.1 - 1.9e-13 50.2 0.8 2.2e-13 50.0 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 GAK63609.1 - 0.00029 20.5 0.5 0.00039 20.1 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3128 PF11326.8 GAK63609.1 - 0.21 12.0 3.6 0.46 10.9 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UCR_hinge PF02320.16 GAK63609.1 - 0.33 11.2 4.9 9.7 6.5 0.4 2.3 1 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein YgaB PF14182.6 GAK63609.1 - 0.4 11.1 3.2 3.9 7.9 1.0 2.0 1 1 1 2 2 2 0 YgaB-like protein DUF2237 PF09996.9 GAK63610.1 - 1.4e-39 134.6 0.0 2.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) LRR_8 PF13855.6 GAK63611.1 - 5.1e-13 48.6 15.9 2.6e-08 33.5 5.7 4.5 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 GAK63611.1 - 2.3e-09 37.4 26.4 3.9e-06 27.1 2.0 5.7 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAK63611.1 - 2.7e-09 36.8 0.6 0.00011 21.7 0.6 2.6 2 0 0 2 2 2 2 Leucine-rich repeat DUF3246 PF11596.8 GAK63611.1 - 6.2 6.2 8.4 1.2 8.5 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) AA_permease_2 PF13520.6 GAK63612.1 - 6.5e-58 196.6 36.3 8.1e-58 196.2 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAK63612.1 - 2.9e-25 88.8 31.8 3.7e-25 88.5 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease FDF PF09532.10 GAK63613.1 - 6.8e-05 23.7 0.4 0.00036 21.4 0.0 2.3 2 0 0 2 2 2 1 FDF domain Thioredoxin_12 PF18400.1 GAK63613.1 - 0.02 14.8 0.3 0.57 10.0 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin-like domain ATG16 PF08614.11 GAK63613.1 - 0.029 14.6 0.8 0.029 14.6 0.8 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) HalX PF08663.10 GAK63613.1 - 0.42 11.0 2.8 16 5.9 0.1 2.8 2 0 0 2 2 2 0 HalX domain DUF2059 PF09832.9 GAK63613.1 - 0.43 10.7 2.6 0.58 10.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) NUDIX PF00293.28 GAK63614.1 - 8.1e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DnaJ_C PF01556.18 GAK63615.1 - 3.4e-36 124.6 0.2 4.9e-36 124.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAK63615.1 - 5.4e-23 80.9 1.4 5.4e-23 80.9 1.4 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAK63615.1 - 4.7e-14 52.5 19.1 7.7e-14 51.8 19.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.6 GAK63615.1 - 0.066 13.7 11.8 0.52 10.8 5.2 2.3 1 1 1 2 2 2 0 Cytochrome c3 Anti-TRAP PF15777.5 GAK63615.1 - 0.15 12.0 17.4 0.046 13.7 4.5 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 GAK63615.1 - 0.41 10.7 11.7 0.59 10.2 7.5 2.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c DZR PF12773.7 GAK63615.1 - 7.4 6.7 8.5 12 6.0 1.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 GAK63615.1 - 7.6 6.6 14.1 2 8.4 4.4 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DcpS PF05652.12 GAK63616.1 - 1.8e-26 93.0 0.0 4.1e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 GAK63616.1 - 6.8e-26 91.0 0.3 1.2e-25 90.2 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding UPF0240 PF06784.11 GAK63617.1 - 0.033 14.3 6.2 0.17 11.9 4.4 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0240) DHBP_synthase PF00926.19 GAK63617.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase S36_mt PF10937.8 GAK63617.1 - 5.1 8.7 9.1 6.4 8.4 7.4 1.9 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial Glyco_hydro_85 PF03644.13 GAK63618.1 - 2.5e-88 296.4 0.0 3.9e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Chitin_synth_1 PF01644.17 GAK63618.1 - 0.21 11.6 0.1 0.37 10.8 0.1 1.3 1 0 0 1 1 1 0 Chitin synthase IU_nuc_hydro PF01156.19 GAK63619.1 - 5e-59 200.4 0.1 6.7e-59 199.9 0.1 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mito_carr PF00153.27 GAK63620.1 - 1e-48 163.2 3.5 2.5e-16 59.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3672 PF12421.8 GAK63620.1 - 0.081 12.8 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Fibronectin type III protein Transthyretin PF00576.21 GAK63621.1 - 1.1e-37 129.1 0.0 1.2e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Big_1 PF02369.16 GAK63621.1 - 0.2 11.7 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF4215 PF13948.6 GAK63624.1 - 0.015 15.7 8.7 2.2 8.8 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4215) PQ-loop PF04193.14 GAK63625.1 - 7e-24 83.4 1.2 1e-11 44.4 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat SNase PF00565.17 GAK63626.1 - 3.8e-20 72.4 1.2 2.1e-08 34.6 0.8 3.2 1 1 1 2 2 2 2 Staphylococcal nuclease homologue GFO_IDH_MocA PF01408.22 GAK63627.1 - 1.8e-14 54.6 0.0 3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAK63627.1 - 1.1e-11 44.7 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_92 PF07971.12 GAK63628.1 - 1.3e-146 489.2 0.0 1.7e-146 488.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAK63628.1 - 3.6e-42 144.9 1.1 6.5e-42 144.1 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Aldose_epim PF01263.20 GAK63629.1 - 1e-59 202.4 0.2 1.3e-59 201.9 0.2 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1275 PF06912.11 GAK63629.1 - 1.7e-20 73.8 14.3 1.7e-20 73.8 14.3 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1275) TMEM65 PF10507.9 GAK63629.1 - 0.068 13.1 0.3 0.45 10.5 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 65 CoA_binding_2 PF13380.6 GAK63630.1 - 1.8e-26 92.9 0.1 2.1e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain Herpes_gp2 PF05955.11 GAK63630.1 - 0.031 13.8 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 FAA_hydrolase PF01557.18 GAK63631.1 - 3.1e-57 193.7 0.0 3.8e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2470 PF10615.9 GAK63632.1 - 7.3e-19 68.2 0.0 1.3e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 GAK63632.1 - 1.2e-05 25.5 0.2 2.2e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) GSHPx PF00255.19 GAK63633.1 - 8.7e-41 137.9 1.3 1.2e-40 137.5 1.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GAK63633.1 - 3.1e-06 27.1 0.3 2e-05 24.5 0.3 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAK63633.1 - 1.4e-05 24.8 0.1 3.1e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 GAK63633.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) MVP_shoulder PF11978.8 GAK63634.1 - 0.045 13.8 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 Shoulder domain S-methyl_trans PF02574.16 GAK63636.1 - 9.5e-43 146.9 0.0 7.5e-42 144.0 0.0 1.9 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Polysacc_deac_1 PF01522.21 GAK63638.1 - 4.5e-21 75.0 0.0 7.9e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Bacteriocin_IId PF09221.10 GAK63638.1 - 0.081 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like Glyco_hydro_57 PF03065.15 GAK63638.1 - 0.17 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Erg28 PF03694.13 GAK63639.1 - 5.3e-38 129.8 2.5 7e-38 129.4 2.5 1.1 1 0 0 1 1 1 1 Erg28 like protein PTR2 PF00854.21 GAK63639.1 - 0.012 14.5 1.0 0.02 13.8 0.6 1.6 1 1 1 2 2 2 0 POT family DNA_ligase_OB_2 PF14743.6 GAK63640.1 - 3.6e-24 84.6 0.1 1.2e-23 82.9 0.1 1.9 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 GAK63640.1 - 8.3e-09 35.4 0.0 3.5e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 GAK63640.1 - 0.028 14.7 0.0 9.4 6.5 0.0 2.6 2 1 0 2 2 2 0 RNA ligase Abhydrolase_3 PF07859.13 GAK63641.1 - 1.2e-39 136.4 0.7 2.6e-32 112.4 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAK63641.1 - 2.8e-09 36.3 0.0 1.6e-08 33.8 0.1 2.0 2 1 0 2 2 2 1 Steryl acetyl hydrolase AXE1 PF05448.12 GAK63641.1 - 0.064 11.9 0.2 0.14 10.8 0.1 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) CDC45 PF02724.14 GAK63641.1 - 1.8 6.8 8.7 0.3 9.3 1.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Neur_chan_memb PF02932.16 GAK63641.1 - 5.4 7.0 10.6 12 5.9 0.2 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ninjurin PF04923.12 GAK63642.1 - 0.064 13.2 0.0 7.6 6.5 0.5 2.6 2 0 0 2 2 2 0 Ninjurin Aldo_ket_red PF00248.21 GAK63643.1 - 1.6e-66 224.5 0.0 2e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family A_deaminase PF00962.22 GAK63644.1 - 4e-26 92.1 0.0 1.3e-25 90.4 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Sulfotransfer_3 PF13469.6 GAK63645.1 - 0.037 14.4 0.0 0.35 11.2 0.0 2.4 3 1 0 3 3 3 0 Sulfotransferase family Mg_trans_NIPA PF05653.14 GAK63647.1 - 3.3e-91 305.4 29.1 4.4e-91 305.0 29.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAK63647.1 - 3.1e-05 24.2 11.5 3.1e-05 24.2 11.5 3.0 2 1 0 2 2 2 1 EamA-like transporter family WSN PF02206.18 GAK63647.1 - 0.011 15.7 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function Neurensin PF14927.6 GAK63647.1 - 5.7 6.6 6.4 16 5.2 0.3 2.9 2 0 0 2 2 2 0 Neurensin Mito_carr PF00153.27 GAK63648.1 - 7.4e-52 173.3 4.5 4.2e-18 65.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein START PF01852.19 GAK63649.1 - 6.6e-11 42.0 0.4 1.1e-10 41.3 0.4 1.3 1 0 0 1 1 1 1 START domain MoaE PF02391.17 GAK63650.1 - 1.8e-38 131.3 0.1 2.5e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 MoaE protein Ribonuclease PF00545.20 GAK63651.1 - 1.1e-08 35.6 0.7 1.5e-08 35.3 0.7 1.2 1 0 0 1 1 1 1 ribonuclease Ustilago_mating PF05722.12 GAK63652.1 - 0.16 11.5 0.1 1.7 8.1 0.1 1.9 2 0 0 2 2 2 0 Ustilago B locus mating-type protein Frag1 PF10277.9 GAK63653.1 - 8.2e-39 133.4 20.4 1e-38 133.1 20.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family PHO4 PF01384.20 GAK63653.1 - 0.52 9.3 8.9 0.84 8.6 8.7 1.4 1 1 0 1 1 1 0 Phosphate transporter family Aminotran_1_2 PF00155.21 GAK63654.1 - 1.6e-16 60.5 0.0 1.9e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAK63654.1 - 3.2e-08 32.8 0.0 9.2e-08 31.3 0.0 1.7 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase NCA2 PF08637.10 GAK63655.1 - 2.8e-80 269.6 4.9 5e-80 268.8 0.0 2.8 3 0 0 3 3 3 1 ATP synthase regulation protein NCA2 Spc29 PF17082.5 GAK63655.1 - 0.084 12.7 0.5 0.5 10.2 0.2 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 Thioredoxin PF00085.20 GAK63656.1 - 7.9e-60 199.3 0.1 1.5e-29 102.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 GAK63656.1 - 1.5e-21 77.1 0.8 5.7e-21 75.2 0.8 2.1 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GAK63656.1 - 2e-17 63.5 0.0 1.9e-07 30.7 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAK63656.1 - 4.7e-13 49.5 0.2 4e-05 24.0 0.2 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAK63656.1 - 6.3e-09 36.1 0.6 0.05 13.9 0.0 4.2 3 2 1 4 4 3 3 Thioredoxin-like AhpC-TSA PF00578.21 GAK63656.1 - 1.6e-08 34.5 0.1 0.003 17.5 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.6 GAK63656.1 - 1.2e-07 31.8 0.5 0.00035 20.7 0.1 3.2 3 0 0 3 3 3 2 Thioredoxin-like HyaE PF07449.11 GAK63656.1 - 1.2e-06 28.5 0.0 0.00038 20.4 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 GAK63656.1 - 9.2e-06 25.6 0.6 0.0032 17.3 0.0 2.7 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 GAK63656.1 - 0.0006 19.6 0.4 1.3 8.7 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.10 GAK63656.1 - 0.00078 19.2 0.1 0.47 10.2 0.0 2.5 2 0 0 2 2 2 2 Redoxin DIM PF08194.12 GAK63656.1 - 0.022 14.9 2.7 0.05 13.8 2.7 1.6 1 0 0 1 1 1 0 DIM protein CotE PF10628.9 GAK63656.1 - 0.045 13.4 0.5 0.094 12.4 0.5 1.5 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) TetR_C_5 PF08360.11 GAK63656.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Thioredoxin_4 PF13462.6 GAK63656.1 - 8.1 6.6 9.5 2.4 8.3 0.1 3.6 3 2 1 4 4 4 0 Thioredoxin XPG_I_2 PF12813.7 GAK63657.1 - 4.2e-07 29.7 0.1 4.4e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 GAK63657.1 - 9.6e-05 22.8 0.0 0.004 17.6 0.0 2.5 1 1 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 GAK63657.1 - 0.0089 15.9 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain Lactamase_B PF00753.27 GAK63658.1 - 7e-15 55.5 2.3 2e-14 54.1 2.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 GAK63658.1 - 1.1e-06 28.6 0.0 4.8e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 GAK63658.1 - 0.0029 17.2 0.1 0.0058 16.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pinin_SDK_N PF04697.13 GAK63658.1 - 0.16 12.6 0.0 0.29 11.8 0.0 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region Evr1_Alr PF04777.13 GAK63659.1 - 5.9e-28 97.3 0.2 1e-27 96.5 0.2 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Glyco_hydro_cc PF11790.8 GAK63660.1 - 2.1e-36 125.7 0.0 3e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Apt1 PF10351.9 GAK63660.1 - 0.005 15.7 16.4 0.0068 15.3 16.4 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Macoilin PF09726.9 GAK63660.1 - 0.09 11.3 29.0 0.12 10.9 29.0 1.1 1 0 0 1 1 1 0 Macoilin family Polyoma_lg_T_C PF06431.11 GAK63660.1 - 0.16 10.8 0.1 0.16 10.8 0.1 2.1 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus Hid1 PF12722.7 GAK63660.1 - 0.65 8.1 7.4 0.89 7.6 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 GAK63660.1 - 2.9 6.6 8.6 4 6.1 8.6 1.2 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 GAK63660.1 - 3.1 7.6 11.0 6.5 6.5 11.0 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Aldose_epim PF01263.20 GAK63661.1 - 8.4e-12 45.0 0.0 1.6e-09 37.5 0.0 2.8 1 1 0 1 1 1 1 Aldose 1-epimerase CIA30 PF08547.12 GAK63662.1 - 3.5e-24 85.6 0.0 6.5e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 GAK63662.1 - 0.047 13.6 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain His_Phos_2 PF00328.22 GAK63663.1 - 1.9e-07 30.8 0.0 0.00013 21.5 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Acatn PF13000.7 GAK63664.1 - 4.3e-159 530.6 23.3 2.8e-79 267.1 14.8 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Peptidase_M48 PF01435.18 GAK63665.1 - 3.2e-32 111.9 0.0 7.8e-32 110.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 HTH_1 PF00126.27 GAK63665.1 - 0.59 10.1 3.9 11 6.0 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family adh_short PF00106.25 GAK63666.1 - 4.3e-22 78.5 2.6 3.5e-10 39.7 0.5 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK63666.1 - 2.9e-14 53.2 0.7 2.1e-06 27.5 0.0 2.5 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK63666.1 - 6.3e-05 23.0 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 KR domain FliG_N PF14842.6 GAK63666.1 - 0.073 13.6 0.1 0.78 10.3 0.0 2.2 2 0 0 2 2 2 0 FliG N-terminal domain SurA_N PF09312.11 GAK63666.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 SurA N-terminal domain FtsJ PF01728.19 GAK63667.1 - 4e-64 216.0 0.0 5.7e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase T3SS_needle_E PF08988.10 GAK63667.1 - 0.12 12.6 0.8 5.8 7.1 0.4 2.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle rRNA_processing PF08524.11 GAK63668.1 - 2.3e-08 34.2 18.3 1.9e-06 28.0 18.3 2.4 1 1 0 1 1 1 1 rRNA processing EBP50_C PF09007.11 GAK63668.1 - 1.5 9.9 9.1 0.33 12.0 1.7 2.2 1 1 1 2 2 2 0 EBP50, C-terminal Methyltransf_PK PF05891.12 GAK63669.1 - 8.5e-61 205.2 0.0 5.6e-34 117.6 0.0 3.0 2 1 1 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 GAK63669.1 - 7.2e-08 32.4 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK63669.1 - 1.6e-06 28.8 0.0 0.0074 17.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAK63669.1 - 6.2e-06 26.9 0.0 0.005 17.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAK63669.1 - 9.1e-05 23.0 0.0 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAK63669.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GRDP-like PF07173.12 GAK63670.1 - 1.7e-16 61.1 0.1 1.7e-13 51.4 0.0 3.3 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like Glyco_transf_15 PF01793.16 GAK63672.1 - 8.7e-110 367.0 2.9 1.1e-109 366.7 2.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase adh_short_C2 PF13561.6 GAK63673.1 - 3e-54 184.0 5.6 8.5e-44 149.8 4.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK63673.1 - 6.4e-49 166.1 4.2 8.1e-49 165.7 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK63673.1 - 1.9e-10 40.9 2.6 3.4e-10 40.1 2.6 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAK63673.1 - 0.0079 16.1 1.1 0.013 15.3 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAK63673.1 - 0.056 13.0 0.3 0.085 12.4 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FYRN PF05964.14 GAK63674.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 F/Y-rich N-terminus Torsin PF06309.11 GAK63675.1 - 6.4e-05 23.0 0.0 0.00035 20.7 0.0 2.0 2 0 0 2 2 2 1 Torsin MobB PF03205.14 GAK63675.1 - 0.00038 20.3 0.0 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 GAK63675.1 - 0.00057 19.6 0.1 0.0015 18.2 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 GAK63675.1 - 0.00066 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAK63675.1 - 0.0016 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin TsaE PF02367.17 GAK63675.1 - 0.0035 17.3 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAK63675.1 - 0.0044 17.4 0.0 0.0057 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GAK63675.1 - 0.005 17.4 0.0 0.017 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 GAK63675.1 - 0.006 16.5 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.15 GAK63675.1 - 0.0069 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NTPase ATP_bind_1 PF03029.17 GAK63675.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 GAK63675.1 - 0.0074 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_11 PF13086.6 GAK63675.1 - 0.0081 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain LpxK PF02606.14 GAK63675.1 - 0.0098 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase KTI12 PF08433.10 GAK63675.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 GAK63675.1 - 0.01 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAK63675.1 - 0.013 15.5 0.0 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 GAK63675.1 - 0.019 14.8 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PRK PF00485.18 GAK63675.1 - 0.02 14.6 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 GAK63675.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 GAK63675.1 - 0.03 14.4 0.1 0.035 14.2 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GAK63675.1 - 0.03 13.8 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase NACHT PF05729.12 GAK63675.1 - 0.03 14.2 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.17 GAK63675.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase 6PF2K PF01591.18 GAK63675.1 - 0.038 13.3 0.0 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MeaB PF03308.16 GAK63675.1 - 0.038 13.0 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GAK63675.1 - 0.044 14.3 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 GAK63675.1 - 0.048 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein SCP1201-deam PF14428.6 GAK63675.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 SCP1.201-like deaminase RNA_helicase PF00910.22 GAK63675.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 GAK63675.1 - 0.092 12.7 0.1 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 GAK63675.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 GAK63675.1 - 0.099 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CNOT1_TTP_bind PF16417.5 GAK63675.1 - 0.15 11.2 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF938 PF06080.12 GAK63676.1 - 2.3e-32 112.4 0.0 7.6e-32 110.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF938) His_Phos_2 PF00328.22 GAK63680.1 - 2.2e-16 60.2 0.0 3.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SPC12 PF06645.13 GAK63681.1 - 5.6e-28 96.8 0.2 6.4e-28 96.6 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ETRAMP PF09716.10 GAK63681.1 - 0.16 12.1 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Fungal_trans PF04082.18 GAK63682.1 - 9.5e-19 67.5 0.5 2.6e-18 66.0 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK63682.1 - 8.8e-08 32.1 8.7 1.5e-07 31.4 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EAF PF09816.9 GAK63683.1 - 5.2e-20 71.7 0.0 2.5e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Alpha-L-AF_C PF06964.12 GAK63683.1 - 1.5e-14 54.5 0.2 5.9e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 GAK63683.1 - 0.0028 17.9 1.0 0.014 15.7 1.0 2.2 1 1 0 1 1 1 1 Carbohydrate binding domain NAD_binding_4 PF07993.12 GAK63685.1 - 4.5e-33 114.5 0.0 9e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAK63685.1 - 1e-27 96.9 0.7 5.4e-27 94.5 0.7 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAK63685.1 - 6.1e-08 32.4 0.0 1.5e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAK63685.1 - 3.9e-05 23.9 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 GAK63685.1 - 0.00019 21.4 0.2 0.00043 20.2 0.2 1.5 1 0 0 1 1 1 1 KR domain Hydrolase PF00702.26 GAK63686.1 - 3.1e-06 27.6 0.0 4.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAK63686.1 - 2.3e-05 24.4 0.0 5.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 GAK63686.1 - 0.0025 17.9 0.0 0.029 14.4 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HTH_53 PF18606.1 GAK63686.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain 7tm_1 PF00001.21 GAK63688.1 - 0.046 13.0 4.7 0.15 11.4 4.8 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DHHC PF01529.20 GAK63689.1 - 1.9e-38 131.6 12.4 7.1e-38 129.7 8.4 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Colicin_V PF02674.16 GAK63689.1 - 0.051 13.5 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 0 Colicin V production protein DZR PF12773.7 GAK63689.1 - 0.73 9.9 7.0 2 8.5 7.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon LIM PF00412.22 GAK63690.1 - 2.6e-20 72.4 16.6 2.4e-11 43.7 6.7 2.4 2 0 0 2 2 2 2 LIM domain DUF4764 PF15961.5 GAK63690.1 - 0.35 9.5 4.8 4.5 5.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) Yippee-Mis18 PF03226.14 GAK63690.1 - 5.6 7.2 6.5 25 5.2 2.8 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PMSR PF01625.21 GAK63691.1 - 4.2e-58 195.9 2.2 5.3e-58 195.5 2.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Exo70 PF03081.15 GAK63692.1 - 8.7e-69 232.4 0.0 1.4e-68 231.7 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.12 GAK63692.1 - 0.61 10.1 2.9 8.7 6.4 0.4 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SLT PF01464.20 GAK63693.1 - 0.00012 21.7 0.8 0.077 12.7 0.0 2.7 3 0 0 3 3 3 2 Transglycosylase SLT domain Macoilin PF09726.9 GAK63693.1 - 0.027 13.0 5.2 0.038 12.5 5.2 1.1 1 0 0 1 1 1 0 Macoilin family LigD_N PF13298.6 GAK63693.1 - 0.077 13.3 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Thiolase_N PF00108.23 GAK63694.1 - 1.5e-66 224.5 0.1 2.1e-66 223.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAK63694.1 - 4.4e-42 142.6 0.1 7.9e-42 141.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAK63694.1 - 0.0014 18.3 0.6 0.0037 16.9 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Glyco_transf_21 PF13506.6 GAK63694.1 - 0.14 11.6 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 Nucleos_tra2_C PF07662.13 GAK63695.1 - 1.8e-64 217.4 6.6 1.8e-64 217.4 6.6 2.4 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 GAK63695.1 - 4.8e-13 49.5 7.4 4.8e-13 49.5 7.4 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 GAK63695.1 - 0.00099 19.4 12.1 0.0082 16.4 9.2 3.4 1 1 1 2 2 2 1 Nucleoside recognition DPM2 PF07297.12 GAK63696.1 - 3.1e-22 78.7 0.0 3.4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 GAK63696.1 - 4.3e-06 26.6 0.1 5e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 GAK63696.1 - 0.0024 17.9 1.4 0.0026 17.8 1.4 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_S24 PF00717.23 GAK63698.1 - 2e-05 24.4 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 GAK63698.1 - 0.0022 17.8 0.0 0.038 13.8 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 DUF3425 PF11905.8 GAK63699.1 - 7e-11 42.2 1.9 9.8e-10 38.5 0.4 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAK63699.1 - 4.5e-08 33.1 8.2 4.5e-08 33.1 8.2 2.3 2 1 0 2 2 2 1 bZIP transcription factor eIF3_subunit PF08597.10 GAK63699.1 - 0.00013 21.9 3.5 0.00013 21.9 3.5 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit CDC45 PF02724.14 GAK63699.1 - 0.16 10.2 18.6 0.025 12.9 5.7 2.1 2 0 0 2 2 2 0 CDC45-like protein XAP5 PF04921.14 GAK63699.1 - 0.29 10.9 18.1 1.6 8.5 2.6 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator GvpL_GvpF PF06386.11 GAK63699.1 - 2 8.3 8.1 5 7.0 8.1 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pex14_N PF04695.13 GAK63699.1 - 6.8 7.3 26.5 0.42 11.3 11.7 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 GAK63699.1 - 7.6 6.4 18.0 2.1 8.3 8.8 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) VHS PF00790.19 GAK63700.1 - 1.5e-26 93.0 0.0 3.4e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAK63700.1 - 9.7e-07 29.0 0.5 1.3e-05 25.4 0.9 2.4 2 0 0 2 2 2 1 GAT domain Tfb4 PF03850.14 GAK63700.1 - 0.58 9.6 2.6 1.1 8.7 2.6 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 Band_3_cyto PF07565.13 GAK63700.1 - 1 9.1 6.5 0.94 9.2 5.0 1.6 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Asp-B-Hydro_N PF05279.11 GAK63701.1 - 2.1 8.4 22.9 54 3.7 21.2 2.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PA26 PF04636.13 GAK63701.1 - 4.9 6.0 6.8 7 5.4 6.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 GAK63701.1 - 6.6 4.9 16.3 12 4.0 16.3 1.4 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GAK63701.1 - 7.8 5.1 7.0 9.7 4.8 7.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Carn_acyltransf PF00755.20 GAK63702.1 - 4.5e-210 699.2 0.0 5.3e-210 699.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF4148 PF13663.6 GAK63704.1 - 0.75 10.0 5.5 1.1 9.6 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) zf-CHY PF05495.12 GAK63706.1 - 2e-13 50.6 12.4 4.4e-13 49.5 12.3 1.5 1 1 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 GAK63706.1 - 0.0047 16.7 3.8 1 9.2 0.1 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR zf-FPG_IleRS PF06827.14 GAK63706.1 - 0.0079 16.0 0.9 0.0079 16.0 0.9 2.3 3 0 0 3 3 1 1 Zinc finger found in FPG and IleRS DUF3797 PF12677.7 GAK63706.1 - 0.21 11.5 2.5 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Zn_Tnp_IS1595 PF12760.7 GAK63706.1 - 0.24 11.4 10.7 6.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 GAK63706.1 - 0.77 9.6 10.2 2 8.2 0.6 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.13 GAK63706.1 - 1 9.4 10.2 0.58 10.2 6.2 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.19 GAK63706.1 - 1.7 8.7 10.0 0.073 13.1 1.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4379 PF14311.6 GAK63706.1 - 2.1 8.8 7.4 1.4 9.4 0.3 2.8 3 0 0 3 3 3 0 Probable Zinc-ribbon domain Evr1_Alr PF04777.13 GAK63706.1 - 4.9 7.7 9.8 99 3.5 9.8 2.7 1 1 0 1 1 1 0 Erv1 / Alr family zinc_ribbon_4 PF13717.6 GAK63706.1 - 5.3 7.1 15.2 7.4 6.6 0.1 4.0 4 1 0 4 4 4 0 zinc-ribbon domain Ofd1_CTDD PF10637.9 GAK63707.1 - 1.9e-93 312.5 0.0 8.9e-89 297.2 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 GAK63707.1 - 1.7e-32 112.0 0.0 3.9e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAK63707.1 - 2.3e-15 57.3 0.0 5.2e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YqzH PF14164.6 GAK63707.1 - 1.3 9.2 3.2 40 4.4 0.0 3.0 3 0 0 3 3 3 0 YqzH-like protein SCP2 PF02036.17 GAK63708.1 - 1.8e-17 63.7 0.0 2.9e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAK63708.1 - 0.0096 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal GPI-anchored PF10342.9 GAK63709.1 - 1.6e-09 38.4 0.7 4.3e-09 37.0 0.0 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Abhydrolase_1 PF00561.20 GAK63710.1 - 3.3e-17 63.0 0.0 6.9e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK63710.1 - 2.1e-05 25.2 1.4 3.7e-05 24.4 1.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAK63710.1 - 0.00086 18.9 0.0 0.0018 17.8 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAK63710.1 - 0.00095 18.5 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAK63710.1 - 0.0086 15.6 0.0 0.076 12.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family EHN PF06441.12 GAK63711.1 - 3.8e-28 98.0 0.3 7.2e-28 97.1 0.3 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAK63711.1 - 2e-10 40.8 0.2 3e-10 40.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK63711.1 - 0.018 15.7 0.2 0.032 14.8 0.2 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PhzC-PhzF PF02567.16 GAK63712.1 - 1e-44 153.1 0.0 1.3e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein PhoD PF09423.10 GAK63713.1 - 7.2e-107 357.4 5.9 9.2e-107 357.1 5.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 GAK63713.1 - 3.1e-24 85.3 0.1 8.3e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 GAK63713.1 - 1.9e-07 31.5 0.9 1.9e-07 31.5 0.9 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain DUF5012 PF16404.5 GAK63713.1 - 0.033 14.3 0.2 0.096 12.8 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) Phytase-like PF13449.6 GAK63714.1 - 2.7e-28 99.7 0.0 4.3e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase Mito_carr PF00153.27 GAK63715.1 - 4.6e-28 97.0 16.3 2.1e-10 40.4 0.7 5.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAK63715.1 - 3.2 6.8 9.0 0.32 10.1 0.1 2.9 3 0 0 3 3 3 0 Gammaproteobacterial serine protease GIY-YIG PF01541.24 GAK63716.1 - 6.9e-09 35.9 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain Arginase PF00491.21 GAK63717.1 - 1.6e-84 283.7 0.0 2.4e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 GAK63717.1 - 0.12 12.5 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain FGGY_C PF02782.16 GAK63718.1 - 2.4e-47 161.2 0.0 4e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAK63718.1 - 1.3e-17 64.2 0.8 8.2e-16 58.3 0.8 2.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 GAK63718.1 - 6.6e-06 25.8 0.7 0.00017 21.2 0.1 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PTH2 PF01981.16 GAK63719.1 - 2.2e-43 147.3 0.2 2.7e-43 147.0 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ADH_N PF08240.12 GAK63720.1 - 5.6e-23 80.9 9.2 1.1e-22 79.9 9.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK63720.1 - 1.2e-18 67.3 0.3 6.4e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK63720.1 - 2.5e-07 31.8 0.0 4.8e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAK63720.1 - 6.2e-05 22.4 0.1 0.00077 18.9 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 GAK63720.1 - 0.0036 16.1 0.0 0.0053 15.5 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.21 GAK63720.1 - 0.0052 16.1 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain OSR1_C PF12202.8 GAK63720.1 - 0.066 13.4 1.8 7 6.9 0.1 2.4 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain 3HCDH_N PF02737.18 GAK63720.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SBF PF01758.16 GAK63721.1 - 3.8e-49 167.0 12.5 3.8e-49 167.0 12.5 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family p450 PF00067.22 GAK63722.1 - 6.9e-55 186.6 0.0 3e-35 121.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Adeno_PV PF03910.13 GAK63722.1 - 0.21 10.3 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DRMBL PF07522.14 GAK63723.1 - 2.5e-27 95.2 0.0 4.5e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAK63723.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAK63723.1 - 0.043 13.8 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RNF220 PF15926.5 GAK63723.1 - 0.058 13.0 0.7 0.12 11.9 0.7 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf_C2HC_14 PF18574.1 GAK63723.1 - 0.08 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain PI-PLC-X PF00388.19 GAK63724.1 - 1.6e-45 154.3 0.0 2.4e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAK63724.1 - 6.1e-38 129.7 0.0 9.8e-38 129.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 GAK63724.1 - 1.8e-06 28.1 0.0 6.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain SET PF00856.28 GAK63726.1 - 2.9e-07 31.0 0.0 2.1e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 SET domain TPR_2 PF07719.17 GAK63726.1 - 0.52 10.6 6.3 0.41 10.9 2.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK63726.1 - 3.1 8.9 7.1 37 5.5 1.8 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 GAK63727.1 - 2.9e-30 105.5 27.8 3.5e-16 59.1 3.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAK63727.1 - 1.7e-18 66.7 51.1 3.7e-12 45.8 27.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.6 GAK63728.1 - 4.6e-20 71.8 0.0 7.9e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK63728.1 - 8.4e-19 67.7 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAK63728.1 - 6.5e-14 52.0 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK63728.1 - 1.6e-05 24.9 0.0 7.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Peptidase_S9 PF00326.21 GAK63729.1 - 6.7e-06 25.7 0.1 1.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAK63729.1 - 0.0014 18.0 0.0 0.0037 16.5 0.0 1.8 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF4115 PF13464.6 GAK63729.1 - 0.029 14.5 0.0 0.089 13.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) Abhydrolase_1 PF00561.20 GAK63729.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold GMC_oxred_N PF00732.19 GAK63730.1 - 2e-74 250.7 0.0 2.5e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK63730.1 - 5.4e-38 130.7 0.1 9.9e-38 129.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAK63730.1 - 0.0025 18.0 0.1 0.011 15.9 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAK63730.1 - 0.0046 16.1 0.2 0.0078 15.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAK63730.1 - 0.0069 16.0 0.3 0.046 13.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK63730.1 - 0.023 13.9 0.0 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK63730.1 - 0.031 13.5 0.0 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 GAK63730.1 - 0.091 11.8 0.1 0.091 11.8 0.1 2.4 3 0 0 3 3 3 0 FAD binding domain Lactamase_B_2 PF12706.7 GAK63731.1 - 2.9e-28 98.7 0.0 1.2e-27 96.8 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_31 PF13847.6 GAK63731.1 - 1.4e-18 67.2 0.0 2.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK63731.1 - 6.5e-07 30.0 0.0 1.5e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK63731.1 - 4e-06 27.4 0.0 8.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAK63731.1 - 5.1e-05 23.3 0.0 7.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Lactamase_B_3 PF13483.6 GAK63731.1 - 6.4e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_23 PF13489.6 GAK63731.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAK63731.1 - 0.029 15.0 0.0 0.07 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAK63731.1 - 0.043 13.4 0.0 0.15 11.6 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase small domain UPF0052 PF01933.18 GAK63732.1 - 9.7e-41 139.9 0.0 2.2e-40 138.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 GalP_UDP_transf PF01087.22 GAK63733.1 - 1.7e-68 230.6 0.5 2.9e-68 229.9 0.5 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 GAK63733.1 - 3.3e-47 160.3 0.0 6.7e-47 159.3 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF2781 PF10914.8 GAK63733.1 - 8.1e-34 117.2 5.8 1.5e-33 116.3 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF4921 PF16268.5 GAK63733.1 - 8.8e-06 24.8 0.1 0.0074 15.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) HIT PF01230.23 GAK63733.1 - 0.012 16.3 0.1 0.031 15.0 0.1 1.6 1 0 0 1 1 1 0 HIT domain Zn_clus PF00172.18 GAK63734.1 - 1.7e-06 28.0 11.3 3.5e-06 27.0 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.23 GAK63736.1 - 0.00083 18.9 0.0 0.0061 16.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1682 PF07946.14 GAK63737.1 - 2.4e-87 293.2 0.0 2.8e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) adh_short PF00106.25 GAK63738.1 - 1.9e-26 92.7 0.0 1.1e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK63738.1 - 7.8e-13 48.5 0.0 7.9e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK63738.1 - 3.7e-08 33.5 0.1 7.6e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAK63738.1 - 0.00058 19.4 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAK63738.1 - 0.0096 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Pmp3 PF01679.17 GAK63739.1 - 3.1e-12 46.5 6.5 4.7e-12 45.9 6.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RRS1 PF04939.12 GAK63739.1 - 0.14 12.1 3.5 0.19 11.6 0.4 2.1 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Thioredoxin_4 PF13462.6 GAK63740.1 - 0.00014 22.1 0.0 0.005 17.0 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin DSBA PF01323.20 GAK63740.1 - 0.027 14.2 0.1 0.87 9.3 0.0 2.4 3 0 0 3 3 3 0 DSBA-like thioredoxin domain MFS_1 PF07690.16 GAK63741.1 - 3.6e-42 144.6 48.0 4.8e-41 140.9 43.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK63741.1 - 9.2e-17 61.0 10.8 9.2e-17 61.0 10.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAK63741.1 - 1.1e-12 47.3 11.7 1.1e-12 47.3 11.7 2.5 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Phage-MuB_C PF09077.11 GAK63741.1 - 0.081 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Mu B transposition protein, C terminal YrhK PF14145.6 GAK63741.1 - 1.9 8.4 7.3 1.5 8.7 0.5 3.3 2 0 0 2 2 2 0 YrhK-like protein ADH_zinc_N PF00107.26 GAK63742.1 - 2.1e-20 73.0 0.2 3.7e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK63742.1 - 4.8e-18 66.5 0.1 3.3e-16 60.5 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK63742.1 - 3e-11 43.1 0.1 8e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAK63742.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PHBC_N PF12551.8 GAK63742.1 - 0.046 13.5 0.3 0.1 12.4 0.3 1.6 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal UPF0242 PF06785.11 GAK63743.1 - 0.037 14.1 0.5 0.037 14.1 0.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_S10 PF00450.22 GAK63744.1 - 8.6e-115 384.5 0.3 1.1e-114 384.1 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase NTF-like PF14540.6 GAK63744.1 - 0.15 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase-like Peptidase_S10 PF00450.22 GAK63747.1 - 2.7e-78 264.2 0.3 3.6e-78 263.8 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 GAK63749.1 - 1.6e-80 271.2 12.1 2.1e-80 270.8 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter GTP_EFTU PF00009.27 GAK63749.1 - 4e-47 160.3 0.0 7e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 GAK63749.1 - 1.3e-39 134.6 0.3 2.3e-39 133.9 0.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus MFS_1 PF07690.16 GAK63749.1 - 2.2e-19 69.6 22.7 1.6e-12 47.1 7.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EFG_C PF00679.24 GAK63749.1 - 3e-17 62.4 0.0 6.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAK63749.1 - 3.5e-07 30.5 0.1 7.2e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAK63749.1 - 0.006 16.7 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 GAK63749.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain ICL PF00463.21 GAK63750.1 - 1.9e-187 623.9 0.2 2.3e-187 623.7 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAK63750.1 - 7.9e-10 38.6 0.1 4.1e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 GAK63750.1 - 0.0084 15.8 0.2 0.024 14.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) SNCAIP_SNCA_bd PF16700.5 GAK63750.1 - 0.045 13.5 0.0 4.4 7.1 0.0 2.9 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain Methyltransf_16 PF10294.9 GAK63751.1 - 1.5e-15 57.3 0.0 3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAK63751.1 - 0.018 15.8 0.1 0.067 13.9 0.1 2.0 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 GAK63751.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 GAK63751.1 - 0.048 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.6 GAK63751.1 - 0.11 12.8 0.1 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pet191_N PF10203.9 GAK63754.1 - 3.3e-26 91.4 3.8 3.8e-26 91.2 3.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Abhydrolase_6 PF12697.7 GAK63755.1 - 0.0055 17.3 2.7 0.0055 17.3 2.7 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1205 PF06722.12 GAK63755.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) MFS_1 PF07690.16 GAK63757.1 - 3.4e-31 108.4 39.1 3.4e-31 108.4 39.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAK63757.1 - 7.4e-06 24.7 0.7 1.1e-05 24.0 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acyl_transf_3 PF01757.22 GAK63758.1 - 1.9e-10 40.3 39.7 1.9e-10 40.3 39.7 2.0 2 0 0 2 2 2 1 Acyltransferase family DUF4381 PF14316.6 GAK63758.1 - 0.019 15.2 0.1 0.5 10.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Glyco_trans_2_3 PF13632.6 GAK63759.1 - 4e-20 72.6 0.8 4e-20 72.6 0.8 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK63759.1 - 1.5e-18 67.6 0.0 2.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAK63759.1 - 9.4e-09 35.0 0.0 2.1e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAK63759.1 - 3.7e-08 33.4 0.0 7.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF2206 PF09971.9 GAK63759.1 - 0.014 14.1 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) CoA_binding PF02629.19 GAK63760.1 - 1.1e-20 74.1 1.2 1.8e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 GAK63760.1 - 2.5e-11 43.6 0.0 6.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAK63760.1 - 0.0013 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 GAK63760.1 - 0.0068 17.2 0.1 0.013 16.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 GAK63760.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Ligase_CoA PF00549.19 GAK63761.1 - 2.1e-10 40.7 0.7 3.4e-10 40.0 0.7 1.3 1 0 0 1 1 1 1 CoA-ligase Peptidase_C12 PF01088.21 GAK63762.1 - 4.1e-54 183.5 0.0 4.8e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med10 PF09748.9 GAK63763.1 - 4.5e-27 94.4 0.1 6.2e-27 94.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex KorB PF08535.10 GAK63763.1 - 0.045 13.8 0.5 1.2 9.2 0.1 2.4 1 1 1 2 2 2 0 KorB domain RCDG1 PF15725.5 GAK63763.1 - 0.24 11.8 6.8 0.46 10.9 6.8 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein CBFD_NFYB_HMF PF00808.23 GAK63764.1 - 4.4e-18 65.3 0.7 7.7e-18 64.5 0.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAK63764.1 - 1.6e-12 47.9 0.1 4.2e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2236 PF09995.9 GAK63764.1 - 3.6e-10 40.4 0.1 7.4e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) G_path_suppress PF15991.5 GAK63764.1 - 1.1 9.3 5.7 2 8.5 5.7 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor tRNA-synt_2 PF00152.20 GAK63765.1 - 7.5e-73 245.3 0.0 1.3e-72 244.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 GAK63765.1 - 2.7e-15 56.2 0.2 3.6e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 GAK63765.1 - 4.4e-07 29.8 0.1 1.2e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAK63765.1 - 0.02 14.4 0.2 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) His_Phos_1 PF00300.22 GAK63766.1 - 2.3e-11 43.7 0.2 3.8e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ADH_zinc_N PF00107.26 GAK63767.1 - 6.1e-23 81.2 0.0 1.6e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAK63767.1 - 1.8e-13 50.3 0.0 4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 GAK63767.1 - 5.1e-09 37.3 0.0 1e-08 36.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AFOR_C PF01314.18 GAK63767.1 - 0.0012 18.0 0.2 0.0016 17.5 0.2 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 ELFV_dehydrog PF00208.21 GAK63767.1 - 0.028 14.2 0.2 0.041 13.6 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Orthopox_A47 PF06334.11 GAK63767.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A47 protein Ysc84 PF04366.12 GAK63768.1 - 1.4e-32 112.1 0.0 3e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator HAD PF12710.7 GAK63768.1 - 5.1e-07 30.3 0.2 1.3e-06 29.0 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4683 PF15735.5 GAK63768.1 - 0.16 11.5 0.5 0.25 10.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) RskA PF10099.9 GAK63770.1 - 0.0091 16.3 0.9 0.011 16.0 0.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Phasin PF05597.11 GAK63770.1 - 0.061 13.3 0.3 0.083 12.9 0.3 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ECH_1 PF00378.20 GAK63771.1 - 2.4e-36 125.4 0.0 3.9e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK63771.1 - 6.5e-18 65.3 0.0 1.1e-16 61.3 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Pterin_4a PF01329.19 GAK63771.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase PWI PF01480.17 GAK63772.1 - 5.2e-31 106.8 0.0 7.4e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 PWI domain SIMPL PF04402.14 GAK63772.1 - 0.017 15.6 0.4 0.027 14.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) KfrA_N PF11740.8 GAK63772.1 - 0.044 14.4 6.6 0.083 13.6 6.6 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Methyltransf_31 PF13847.6 GAK63773.1 - 0.0028 17.5 0.0 0.0058 16.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain BUD22 PF09073.10 GAK63774.1 - 0.0019 17.7 12.5 0.0025 17.2 12.5 1.2 1 0 0 1 1 1 1 BUD22 PIEZO PF15917.5 GAK63774.1 - 0.076 12.5 1.7 0.11 11.9 1.7 1.2 1 0 0 1 1 1 0 Piezo Selenoprotein_S PF06936.11 GAK63774.1 - 0.08 12.7 1.7 0.14 12.0 1.7 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Borrelia_P83 PF05262.11 GAK63774.1 - 0.4 9.1 10.3 0.56 8.6 10.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1682 PF07946.14 GAK63774.1 - 1 8.5 10.0 1.4 8.1 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Paf1 PF03985.13 GAK63774.1 - 1.7 7.5 10.3 2.5 7.0 10.3 1.1 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 GAK63774.1 - 3.5 7.5 21.1 11 5.9 21.1 1.8 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 GAK63774.1 - 4 6.9 6.5 4.7 6.7 5.9 1.7 2 0 0 2 2 2 0 PPP4R2 Phage_B PF02304.15 GAK63775.1 - 0.1 13.0 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Scaffold protein B dCMP_cyt_deam_1 PF00383.23 GAK63776.1 - 3.7e-14 52.4 0.0 9.4e-14 51.1 0.0 1.7 1 1 1 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 GAK63776.1 - 2e-11 44.2 0.9 2.3e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 GAK63776.1 - 0.0022 17.7 1.0 0.036 13.7 0.0 2.3 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases MFS_1 PF07690.16 GAK63777.1 - 1.4e-19 70.2 26.5 8.1e-14 51.3 14.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily NTP_transf_9 PF04248.12 GAK63777.1 - 8.8e-18 64.0 0.0 1.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Sugar_tr PF00083.24 GAK63777.1 - 4.3e-05 22.6 0.1 4.3e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.8 GAK63777.1 - 0.00034 19.4 5.2 0.00034 19.4 5.2 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Na_H_Exchanger PF00999.21 GAK63780.1 - 3.9e-55 187.2 19.2 5.1e-55 186.8 19.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 GAK63780.1 - 0.0018 18.3 1.3 0.029 14.5 0.0 2.8 3 0 0 3 3 3 1 YrhC-like protein FGGY_C PF02782.16 GAK63781.1 - 1.6e-15 57.3 0.0 3.9e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAK63781.1 - 5.3e-09 36.0 0.0 7.6e-06 25.7 0.0 3.5 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain NMO PF03060.15 GAK63782.1 - 3.5e-37 128.6 5.2 8.1e-28 97.8 0.5 2.2 2 1 0 2 2 2 2 Nitronate monooxygenase CoA_transf_3 PF02515.17 GAK63783.1 - 9.5e-125 416.5 0.0 1.2e-124 416.2 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Got1 PF04178.12 GAK63784.1 - 1.4e-23 83.4 22.9 2e-23 83.0 22.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.8 GAK63784.1 - 0.069 13.4 0.7 0.069 13.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3021 PF11457.8 GAK63784.1 - 0.19 12.0 22.2 0.3 11.4 22.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF2157 PF09925.9 GAK63784.1 - 0.43 10.4 15.2 0.57 10.0 15.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Zn_clus PF00172.18 GAK63785.1 - 0.00013 22.0 10.3 0.00025 21.1 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAK63785.1 - 0.0037 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF4212 PF13937.6 GAK63786.1 - 0.23 11.9 0.9 1.3 9.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF2069 PF09842.9 GAK63786.1 - 0.62 10.3 8.7 0.11 12.7 3.3 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2069) Allantoicase PF03561.15 GAK63787.1 - 1.9e-87 290.6 0.0 8.9e-44 149.0 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 GAK63787.1 - 6.3e-51 172.8 0.1 9.4e-51 172.2 0.1 1.3 1 0 0 1 1 1 1 Ureidoglycolate lyase PAF-AH_p_II PF03403.13 GAK63788.1 - 2.6e-47 161.2 0.0 2.8e-43 147.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 GAK63788.1 - 1.1e-05 24.8 0.1 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAK63788.1 - 0.0043 16.0 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme HAD_2 PF13419.6 GAK63788.1 - 0.0043 17.1 0.0 0.97 9.5 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Esterase PF00756.20 GAK63788.1 - 0.045 13.4 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 GAK63788.1 - 1.9 9.0 16.1 0.1 13.2 6.8 3.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family PRT_C PF08372.10 GAK63789.1 - 0.19 11.5 1.4 3.1 7.5 0.2 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal SNARE PF05739.19 GAK63790.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 SNARE domain MIP PF00230.20 GAK63792.1 - 6.6e-44 150.3 2.4 8.8e-44 149.9 2.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Retrotran_gag_2 PF14223.6 GAK63792.1 - 0.038 13.7 0.3 0.066 12.9 0.3 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type 2TM PF13239.6 GAK63792.1 - 0.54 10.6 9.7 1.8 9.0 0.0 3.4 2 1 1 3 3 3 0 2TM domain DNA_pol_B PF00136.21 GAK63793.1 - 1.3e-99 334.0 0.0 1.7e-99 333.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAK63793.1 - 1.3e-22 80.4 0.0 1.5e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAK63793.1 - 7.3e-12 45.6 9.9 1.5e-11 44.6 9.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta MutL_C PF08676.11 GAK63794.1 - 1.6e-22 79.9 0.0 4.1e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 GAK63794.1 - 1.9e-19 69.5 0.0 4.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAK63794.1 - 1.4e-10 41.2 0.0 2.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAK63794.1 - 1.1e-05 25.9 0.0 2.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase STAT_bind PF02864.15 GAK63794.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 STAT protein, DNA binding domain RRP7 PF12923.7 GAK63795.1 - 0.047 13.8 0.6 0.067 13.3 0.6 1.2 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF3585 PF12130.8 GAK63795.1 - 0.051 13.7 5.7 0.21 11.7 5.7 1.8 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain ArsR PF09824.9 GAK63795.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator FIN1 PF17300.2 GAK63795.1 - 0.36 10.3 3.4 0.85 9.1 3.4 1.5 1 1 0 1 1 1 0 Filaments in between nuclei protein-1 Enkurin PF13864.6 GAK63795.1 - 0.48 10.9 4.5 2.8 8.4 4.2 2.0 1 1 1 2 2 2 0 Calmodulin-binding ERG2_Sigma1R PF04622.12 GAK63796.1 - 1.5e-89 298.9 0.0 1.9e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Rhodanese PF00581.20 GAK63797.1 - 4.7e-05 23.9 0.0 0.00012 22.5 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain KduI PF04962.12 GAK63797.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family AMP-binding PF00501.28 GAK63798.1 - 5.1e-80 269.1 0.1 1e-53 182.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 GAK63798.1 - 1.1e-11 45.5 0.1 1.4e-10 42.0 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.28 GAK63799.1 - 2.7e-13 50.9 1.6 4.2e-13 50.3 1.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EHN PF06441.12 GAK63800.1 - 1.4e-28 99.4 0.1 2.7e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAK63800.1 - 5e-07 29.6 0.1 1.3e-06 28.3 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK63800.1 - 0.00056 20.6 3.1 0.003 18.2 3.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L37 PF08561.10 GAK63801.1 - 1.2e-29 103.3 5.0 1.6e-29 102.8 5.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 NARP1 PF12569.8 GAK63801.1 - 0.05 12.5 8.1 0.065 12.1 8.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CUE PF02845.16 GAK63802.1 - 3.7e-11 42.5 0.0 6.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF4834 PF16118.5 GAK63802.1 - 0.24 12.4 0.9 0.8 10.7 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_M19 PF01244.21 GAK63803.1 - 2.1e-86 290.0 0.0 2.9e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Abhydrolase_6 PF12697.7 GAK63803.1 - 2.6e-07 31.5 1.6 2.6e-07 31.5 1.6 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK63803.1 - 0.02 14.2 0.0 0.046 13.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_31 PF01055.26 GAK63804.1 - 1.5e-79 268.2 0.0 2e-79 267.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAK63804.1 - 1.4e-09 38.1 0.1 5.1e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 GAK63804.1 - 0.061 13.6 0.0 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) MFS_1 PF07690.16 GAK63805.1 - 1.3e-34 119.7 21.5 1.6e-34 119.4 21.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_32N PF00251.20 GAK63806.1 - 1.1e-85 287.9 6.9 1.5e-85 287.4 6.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAK63806.1 - 1.9e-12 47.5 0.3 3.6e-12 46.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_88 PF07470.13 GAK63807.1 - 2.8e-75 253.5 0.9 3.9e-75 253.1 0.9 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pec_lyase PF09492.10 GAK63807.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Pectic acid lyase peroxidase PF00141.23 GAK63810.1 - 7.2e-48 163.3 0.0 1.1e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PXA PF02194.15 GAK63811.1 - 1.8e-41 142.1 0.6 3.1e-39 134.8 0.0 3.2 2 1 0 3 3 3 1 PXA domain Nexin_C PF08628.12 GAK63811.1 - 0.0029 18.2 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal Acetyltransf_3 PF13302.7 GAK63812.1 - 2.4e-14 54.2 0.0 4.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK63812.1 - 1.1e-05 25.6 0.0 1.8e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GIDE PF12483.8 GAK63812.1 - 0.078 12.4 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 E3 Ubiquitin ligase UvdE PF03851.14 GAK63813.1 - 1.8e-85 286.5 0.0 2.5e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE RCC1 PF00415.18 GAK63814.1 - 1.8e-25 89.3 14.7 2.9e-14 53.4 0.0 8.2 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAK63814.1 - 9.6e-16 57.1 9.6 9e-09 34.9 0.3 6.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat 4HBT PF03061.22 GAK63816.1 - 1.5e-10 41.3 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily N6-adenineMlase PF10237.9 GAK63817.1 - 3.6e-34 117.9 0.1 1.2e-33 116.1 0.1 1.8 1 1 0 1 1 1 1 Probable N6-adenine methyltransferase PRELI PF04707.14 GAK63818.1 - 7.5e-40 136.3 0.0 9.3e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF3530 PF12048.8 GAK63818.1 - 0.093 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Glyco_hydro_47 PF01532.20 GAK63819.1 - 2.2e-132 442.2 0.0 2.6e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Acetyltransf_11 PF13720.6 GAK63819.1 - 0.19 12.2 0.0 0.5 10.9 0.0 1.7 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 WES_acyltransf PF03007.16 GAK63821.1 - 1.4e-12 47.9 0.0 1.4e-12 47.9 0.0 2.7 2 2 3 5 5 5 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 GAK63821.1 - 2e-09 37.6 0.0 3.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) DSBA PF01323.20 GAK63823.1 - 1.6e-05 24.8 0.1 4e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.25 GAK63824.1 - 8.2e-22 77.6 0.0 1.1e-19 70.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK63824.1 - 7.9e-13 48.5 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK63824.1 - 0.0046 16.9 0.1 0.0079 16.1 0.1 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAK63824.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.8 GAK63825.1 - 2e-12 46.6 0.1 2.3e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK63825.1 - 1.7e-09 37.6 11.8 2.9e-09 36.9 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GalKase_gal_bdg PF10509.9 GAK63826.1 - 1.5e-21 75.6 0.1 3.2e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 GAK63826.1 - 8.1e-13 48.5 0.3 2.7e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAK63826.1 - 8.2e-13 48.4 0.2 8.2e-13 48.4 0.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF3914 PF13053.6 GAK63826.1 - 0.053 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Zn_clus PF00172.18 GAK63827.1 - 2e-05 24.6 11.1 3.8e-05 23.7 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK63827.1 - 0.00024 20.3 0.1 0.00041 19.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAK63828.1 - 2.8e-34 118.6 54.0 1.1e-33 116.7 53.2 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK63828.1 - 1.3e-09 37.5 12.5 1.3e-09 37.5 12.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter FPN1 PF06963.12 GAK63829.1 - 5.4e-138 460.2 11.3 6.8e-138 459.9 11.3 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) ACOX PF01756.19 GAK63830.1 - 1.4e-35 122.5 0.0 6.2e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAK63830.1 - 4.6e-20 72.4 0.9 9.2e-20 71.5 0.9 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAK63830.1 - 1.7e-05 24.9 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAK63830.1 - 0.00017 21.8 0.1 0.00042 20.6 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TAL_effector PF03377.13 GAK63830.1 - 0.038 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 TAL effector repeat Pyr_redox_2 PF07992.14 GAK63831.1 - 8.6e-24 84.3 0.6 1.1e-23 83.9 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK63831.1 - 9.6e-07 28.3 0.0 1.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK63831.1 - 1.1e-06 29.1 1.4 1.8e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK63831.1 - 7.5e-06 25.3 0.3 0.0032 16.8 0.1 2.3 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.6 GAK63831.1 - 2.5e-05 23.6 0.0 6.8e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 GAK63831.1 - 0.00024 20.3 1.9 0.038 13.0 0.2 2.7 2 1 1 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 GAK63831.1 - 0.00072 18.4 4.0 0.12 11.1 0.1 3.3 3 1 0 3 3 3 2 HI0933-like protein DAO PF01266.24 GAK63831.1 - 0.00087 19.0 6.5 0.071 12.7 0.2 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAK63831.1 - 0.0073 16.5 1.1 0.03 14.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAK63831.1 - 0.036 12.9 0.3 0.036 12.9 0.3 1.8 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 GAK63831.1 - 0.17 11.9 5.1 20 5.2 0.0 3.7 3 1 0 4 4 4 0 FAD-NAD(P)-binding Arrestin_C PF02752.22 GAK63832.1 - 1.5e-20 74.0 0.0 1e-19 71.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAK63832.1 - 1.2e-08 35.1 0.0 3.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Sgf11 PF08209.11 GAK63833.1 - 4.3e-15 55.0 0.5 8.9e-15 54.0 0.5 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Molybdop_Fe4S4 PF04879.16 GAK63833.1 - 0.077 13.0 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain zf-C2HC_2 PF13913.6 GAK63833.1 - 2.2 8.3 5.3 0.24 11.4 0.4 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Calc_CGRP_IAPP PF00214.19 GAK63834.1 - 0.1 13.0 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family GFA PF04828.14 GAK63835.1 - 7.7e-20 71.0 0.2 1e-19 70.6 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 GAK63835.1 - 0.0083 16.1 3.3 0.069 13.2 0.0 2.2 2 0 0 2 2 2 1 Double zinc ribbon zf-LITAF-like PF10601.9 GAK63835.1 - 0.01 16.1 1.3 1.6 9.1 0.0 2.3 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain Zn_ribbon_SprT PF17283.2 GAK63835.1 - 0.016 15.1 3.2 0.29 11.1 0.4 2.4 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 GAK63835.1 - 0.024 14.3 3.5 0.084 12.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 GAK63835.1 - 0.047 13.6 0.1 0.047 13.6 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-ISL3 PF14690.6 GAK63835.1 - 0.18 12.5 4.0 0.82 10.4 0.5 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 NOB1_Zn_bind PF08772.11 GAK63835.1 - 0.31 11.2 7.0 2.7 8.2 6.4 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 GAK63835.1 - 0.44 10.7 0.1 0.44 10.7 0.1 2.4 2 1 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 GAK63835.1 - 0.69 10.0 8.4 0.24 11.4 1.4 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_4 PF13717.6 GAK63835.1 - 3.5 7.6 8.9 0.44 10.5 2.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 GAK63835.1 - 5.7 6.7 8.7 0.37 10.5 0.3 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cyanate_lyase PF02560.14 GAK63836.1 - 1.1e-33 114.8 0.0 1.6e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 GAK63836.1 - 0.0009 19.5 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 GAK63836.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix SNase PF00565.17 GAK63837.1 - 4e-43 146.3 0.2 3.8e-18 65.9 0.0 6.3 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 GAK63837.1 - 2.4e-16 59.9 0.0 4.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 GAK63837.1 - 0.0019 18.6 0.0 0.028 14.9 0.0 2.7 2 0 0 2 2 2 1 Agenet domain SMN PF06003.12 GAK63837.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zn_clus PF00172.18 GAK63838.1 - 4.5e-07 29.9 6.7 8.9e-07 28.9 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apt1 PF10351.9 GAK63839.1 - 5.8 5.6 12.7 7.7 5.2 12.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAD_binding_2 PF03446.15 GAK63840.1 - 1e-35 123.2 2.0 1.7e-35 122.5 2.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAK63840.1 - 1e-32 113.0 2.9 1e-32 112.9 0.9 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Collagen PF01391.18 GAK63840.1 - 6.6e-10 38.6 84.6 0.0003 20.5 26.1 4.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) F420_oxidored PF03807.17 GAK63840.1 - 0.0004 20.9 0.6 0.00095 19.7 0.6 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GAK63840.1 - 0.0011 18.9 1.1 0.0018 18.2 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAK63840.1 - 0.0021 17.5 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CAP_N PF01213.19 GAK63840.1 - 0.027 14.0 3.4 0.086 12.3 3.4 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GAK63840.1 - 0.15 12.1 2.1 0.48 10.5 2.1 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 GAK63840.1 - 1.1 9.3 3.4 2.6 8.1 3.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MTS PF05175.14 GAK63842.1 - 6.9e-10 38.7 0.0 5.2e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_33 PF10017.9 GAK63842.1 - 1.2e-05 24.7 0.0 0.00077 18.7 0.0 2.1 1 1 1 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_24 PF13578.6 GAK63842.1 - 1.8e-05 25.7 0.0 7.9e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK63842.1 - 0.00011 22.9 0.0 0.00024 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK63842.1 - 0.00079 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAK63842.1 - 0.039 13.7 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 GAK63842.1 - 0.052 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 GAK63842.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 GAK63842.1 - 0.11 13.2 0.0 0.39 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_7 PF03441.14 GAK63842.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase p450 PF00067.22 GAK63843.1 - 7e-61 206.4 0.0 1.7e-60 205.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.21 GAK63844.1 - 1.5e-13 51.0 2.6 1.8e-10 40.9 0.5 2.5 2 0 0 2 2 2 2 Acyl transferase domain MFS_1 PF07690.16 GAK63845.1 - 7.1e-36 123.8 74.4 1e-30 106.9 56.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily YlaH PF14036.6 GAK63845.1 - 0.16 12.3 4.8 0.099 13.0 1.4 2.4 2 0 0 2 2 2 0 YlaH-like protein PhoLip_ATPase_C PF16212.5 GAK63846.1 - 4.9 6.8 11.9 0.81 9.4 5.5 2.1 1 1 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal ADH_N PF08240.12 GAK63847.1 - 7.2e-29 99.9 0.6 1.2e-28 99.2 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK63847.1 - 3.4e-25 88.5 0.4 5.5e-25 87.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK63847.1 - 9.8e-09 36.4 0.2 1.9e-08 35.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAK63847.1 - 0.057 12.9 0.1 0.14 11.6 0.2 1.6 2 0 0 2 2 2 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 GAK63847.1 - 0.09 12.1 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain mono-CXXC PF15626.6 GAK63847.1 - 3.3 8.2 5.5 1.3 9.4 0.8 2.3 2 0 0 2 2 2 0 single CXXC unit Thiolase_N PF00108.23 GAK63850.1 - 3.6e-17 62.6 0.2 1.3e-14 54.3 0.0 2.5 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAK63850.1 - 5.6e-09 35.7 0.5 7.9e-08 32.0 0.1 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAK63850.1 - 9.7e-06 25.3 3.3 0.00012 21.7 2.0 2.3 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 GAK63850.1 - 0.0017 17.2 0.2 0.019 13.7 0.2 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 GAK63850.1 - 0.0024 17.7 3.1 0.015 15.1 0.4 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 GAK63850.1 - 0.13 12.3 0.7 0.87 9.6 0.0 2.6 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain GFO_IDH_MocA PF01408.22 GAK63852.1 - 2.6e-18 67.0 0.0 4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CRCB PF02537.15 GAK63853.1 - 1.6e-32 111.7 18.9 7.3e-19 67.9 6.5 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) SKA2 PF16740.5 GAK63856.1 - 0.046 13.5 1.3 0.09 12.6 1.3 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 zf-ZPR1 PF03367.13 GAK63856.1 - 0.08 12.8 0.6 0.15 11.9 0.6 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Methyltrans_RNA PF04452.14 GAK63856.1 - 0.15 11.4 0.3 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 RNA methyltransferase Macoilin PF09726.9 GAK63856.1 - 0.24 9.9 4.1 0.31 9.5 4.1 1.1 1 0 0 1 1 1 0 Macoilin family DDE_Tnp_4 PF13359.6 GAK63857.1 - 1.2e-15 57.6 0.0 1.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAK63857.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Actino_peptide PF14408.6 GAK63858.1 - 0.0037 17.3 4.0 0.0059 16.7 4.0 1.2 1 0 0 1 1 1 1 Ribosomally synthesised peptide in actinomycetes SNF2_N PF00176.23 GAK63859.1 - 2e-44 151.8 0.0 3.8e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK63859.1 - 1.7e-08 34.8 0.1 4.1e-07 30.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 GAK63859.1 - 1.7e-06 27.7 10.6 3.1e-06 27.0 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK63859.1 - 1.5e-05 24.8 12.1 3e-05 23.8 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK63859.1 - 5.1e-05 23.1 12.9 8.7e-05 22.3 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK63859.1 - 0.00031 20.5 11.2 0.00057 19.7 11.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAK63859.1 - 0.00067 19.9 13.8 0.0012 19.1 13.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAK63859.1 - 0.0012 18.8 12.6 0.002 18.1 12.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.6 GAK63859.1 - 0.024 14.8 5.1 0.055 13.6 5.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 GAK63859.1 - 0.083 12.5 11.2 0.16 11.6 11.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 GAK63859.1 - 0.27 11.4 10.3 0.52 10.5 10.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAK63859.1 - 0.45 10.6 11.9 0.91 9.6 11.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger M20_dimer PF07687.14 GAK63861.1 - 8.5e-12 45.0 1.0 1.3e-11 44.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAK63861.1 - 2.5e-08 33.9 1.1 2.8e-08 33.7 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 CTK3_C PF12350.8 GAK63861.1 - 1 9.5 3.3 0.52 10.5 0.4 1.9 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus NMO PF03060.15 GAK63862.1 - 0.1 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase NMO PF03060.15 GAK63863.1 - 5.6e-42 144.3 4.3 5e-41 141.2 4.3 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase DUF1275 PF06912.11 GAK63863.1 - 1.6e-33 116.3 9.8 2.8e-33 115.5 9.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) IMPDH PF00478.25 GAK63863.1 - 3.3e-10 39.5 0.4 1.2e-07 31.1 0.4 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAK63863.1 - 0.0077 15.3 0.3 0.014 14.4 0.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NrsF PF06532.11 GAK63863.1 - 0.0095 15.7 2.2 0.0095 15.7 2.2 3.0 4 0 0 4 4 4 1 Negative regulator of sigma F His_biosynth PF00977.21 GAK63863.1 - 0.043 13.3 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.17 GAK63863.1 - 0.05 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase SNARE_assoc PF09335.11 GAK63863.1 - 4.8 7.7 7.3 0.81 10.2 1.5 2.7 3 1 0 3 3 3 0 SNARE associated Golgi protein DUF3040 PF11239.8 GAK63863.1 - 5.8 7.3 6.2 1.2 9.5 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Abhydrolase_4 PF08386.10 GAK63864.1 - 7.2e-21 74.2 0.0 1.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 GAK63864.1 - 9.7e-20 71.3 0.0 1.7e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.7 GAK63865.1 - 5.8e-11 42.1 1.4 2.8e-10 39.9 1.4 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK63865.1 - 0.0017 18.2 0.1 0.014 15.3 0.3 2.3 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.16 GAK63866.1 - 1.3e-41 142.8 34.1 1.3e-41 142.8 34.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK63866.1 - 2.9e-12 46.2 10.3 2.9e-12 46.2 10.3 2.8 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAK63866.1 - 1.3e-11 43.7 1.6 2.1e-11 43.0 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 GAK63866.1 - 5.4e-09 35.8 3.2 1.1e-08 34.9 3.2 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF3611 PF12263.8 GAK63866.1 - 0.27 11.1 0.0 0.27 11.1 0.0 3.6 3 1 0 4 4 4 0 Protein of unknown function (DUF3611) DUF4042 PF13251.6 GAK63869.1 - 1.6e-14 54.0 9.5 7.2e-09 35.6 0.2 5.7 6 0 0 6 6 6 3 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 GAK63869.1 - 0.00099 19.5 36.3 0.16 12.4 1.2 8.6 6 3 3 9 9 9 4 HEAT repeats Cnd1 PF12717.7 GAK63869.1 - 0.0052 16.8 0.2 6.3 6.8 0.0 4.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 AraC_N PF06719.13 GAK63869.1 - 0.12 12.0 4.9 2 8.1 0.5 3.5 2 1 1 3 3 3 0 AraC-type transcriptional regulator N-terminus HEAT PF02985.22 GAK63869.1 - 0.34 11.3 29.4 0.45 10.9 0.2 7.8 9 0 0 9 9 9 0 HEAT repeat Pterin_4a PF01329.19 GAK63870.1 - 5e-28 97.1 0.2 6.3e-28 96.8 0.2 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase GST_C_6 PF17171.4 GAK63871.1 - 0.0015 18.3 0.1 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 GAK63871.1 - 0.043 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex Sulfate_transp PF00916.20 GAK63871.1 - 0.13 11.0 0.2 0.19 10.4 0.2 1.2 1 0 0 1 1 1 0 Sulfate permease family DUF3325 PF11804.8 GAK63871.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) LRR_6 PF13516.6 GAK63872.1 - 0.00036 20.3 6.1 2.9 8.2 0.0 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 GAK63872.1 - 0.014 15.8 9.5 0.55 10.7 0.2 4.4 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GAK63872.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 GAK63872.1 - 0.17 12.6 5.4 29 5.7 0.0 5.4 3 2 1 4 4 4 0 Leucine Rich Repeat Hydrolase_4 PF12146.8 GAK63873.1 - 1.8e-13 50.3 2.0 1.1e-11 44.4 0.5 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK63873.1 - 1.8e-10 41.8 4.5 4.3e-10 40.6 4.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAK63873.1 - 4.3e-09 36.4 0.1 8e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAK63873.1 - 2.5e-08 34.0 0.6 4.2e-08 33.3 0.6 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAK63873.1 - 0.00046 19.9 0.1 0.00077 19.1 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 GAK63873.1 - 0.0006 18.8 0.1 0.00085 18.3 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAK63873.1 - 0.00071 19.1 1.0 0.015 14.8 0.3 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 GAK63873.1 - 0.0088 15.7 0.4 0.06 13.0 0.4 2.0 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 GAK63873.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase PF00151.19 GAK63873.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipase DUF818 PF05677.12 GAK63873.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) HMGL-like PF00682.19 GAK63874.1 - 1.9e-46 158.7 0.0 2.5e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 HMGL-like PGG PF13962.6 GAK63875.1 - 0.042 13.7 0.3 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF3074 PF11274.8 GAK63876.1 - 1.2e-45 155.8 0.1 1.6e-45 155.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ACC_epsilon PF13822.6 GAK63878.1 - 0.39 11.4 5.3 0.14 12.9 2.1 1.8 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ham1p_like PF01725.16 GAK63879.1 - 8.1e-53 179.1 0.0 9.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family MFS_1 PF07690.16 GAK63880.1 - 2.7e-26 92.3 24.1 3.4e-26 92.0 24.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DAHP_synth_2 PF01474.16 GAK63881.1 - 1.9e-166 553.9 0.0 2.9e-166 553.3 0.0 1.3 1 1 0 1 1 1 1 Class-II DAHP synthetase family TOH_N PF12549.8 GAK63882.1 - 6.1 6.8 12.7 0.23 11.4 0.2 3.8 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal XRCC4 PF06632.12 GAK63882.1 - 8.9 5.1 9.9 33 3.2 0.0 2.4 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3292 PF11696.8 GAK63883.1 - 0.0001 20.9 0.5 0.0001 20.9 0.5 3.6 5 0 0 5 5 5 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 GAK63883.1 - 0.00018 21.3 0.3 0.73 9.6 0.0 2.5 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 GAK63883.1 - 0.0047 16.9 2.8 2.2 8.2 1.0 2.4 2 0 0 2 2 2 2 Reticulon MeaB PF03308.16 GAK63883.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 GAK63883.1 - 0.026 13.8 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 GAK63883.1 - 0.027 14.2 0.0 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAK63883.1 - 0.029 14.9 0.0 0.11 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAK63883.1 - 0.091 13.1 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 GAK63883.1 - 0.12 11.5 0.1 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 GAK63883.1 - 0.74 10.0 3.9 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain Methyltransf_23 PF13489.6 GAK63884.1 - 0.00013 21.8 0.0 0.00045 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK63884.1 - 0.00036 20.3 0.0 0.52 10.1 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Rhodanese PF00581.20 GAK63884.1 - 0.0066 17.0 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_25 PF13649.6 GAK63884.1 - 0.04 14.6 0.0 17 6.2 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain PRK PF00485.18 GAK63885.1 - 4.3e-53 180.0 0.0 8.6e-53 179.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 GAK63885.1 - 5.8e-44 150.0 0.1 8.8e-42 142.9 0.0 2.3 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.6 GAK63885.1 - 4e-06 27.4 0.0 7.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 GAK63885.1 - 0.0001 22.1 0.1 0.00024 20.8 0.0 1.6 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_33 PF13671.6 GAK63885.1 - 0.00017 21.7 0.0 0.00051 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 GAK63885.1 - 0.00048 20.0 0.0 0.00099 19.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 GAK63885.1 - 0.068 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pkinase_fungal PF17667.1 GAK63885.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase AAA_28 PF13521.6 GAK63885.1 - 0.14 12.4 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.28 GAK63886.1 - 7.6e-12 45.2 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF667 PF05018.13 GAK63887.1 - 1.3e-12 47.9 0.0 2.9e-06 27.1 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF667) hSac2 PF12456.8 GAK63888.1 - 8.3e-27 93.2 0.0 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Syja_N PF02383.18 GAK63889.1 - 5e-91 305.3 0.0 7.8e-91 304.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Apt1 PF10351.9 GAK63889.1 - 0.79 8.5 9.3 1.5 7.6 3.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Polysacc_deac_1 PF01522.21 GAK63890.1 - 1.7e-29 102.2 0.0 2.8e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Tma16 PF11176.8 GAK63891.1 - 2.4e-40 137.8 0.5 1.1e-39 135.6 0.0 2.1 2 0 0 2 2 2 1 Translation machinery-associated protein 16 DUF3678 PF12435.8 GAK63891.1 - 1.1 8.7 6.4 1.8 8.0 1.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) RTA1 PF04479.13 GAK63892.1 - 3.9e-40 137.7 16.5 1e-32 113.5 4.5 3.0 4 0 0 4 4 4 2 RTA1 like protein DUF350 PF03994.14 GAK63892.1 - 0.014 15.5 1.8 0.014 15.5 1.8 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF350) Zn_clus PF00172.18 GAK63893.1 - 0.0044 17.1 7.7 0.0094 16.1 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 GAK63894.1 - 7.4e-42 143.7 0.1 1.3e-41 142.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK63894.1 - 3.1e-22 79.7 0.0 2e-21 77.1 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAK63894.1 - 2.9e-06 26.6 3.0 0.028 13.5 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 GAK63894.1 - 9.7e-05 21.8 0.4 0.00015 21.1 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAK63894.1 - 0.013 14.7 0.6 0.056 12.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK63894.1 - 0.033 14.4 1.5 0.09 13.0 1.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK63894.1 - 0.076 12.6 4.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase MatE PF01554.18 GAK63895.1 - 1.2e-54 184.3 26.3 7.5e-29 100.5 8.7 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAK63895.1 - 1.1e-05 25.6 10.7 1.1e-05 25.6 10.7 3.7 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Acetyltransf_1 PF00583.25 GAK63896.1 - 4.1e-13 49.6 0.0 5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK63896.1 - 1.7e-11 44.4 0.0 3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAK63896.1 - 3.6e-10 39.8 0.0 4.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAK63896.1 - 0.00033 21.3 0.0 0.00041 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAK63896.1 - 0.001 19.2 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Amidohydro_2 PF04909.14 GAK63897.1 - 1.7e-37 129.8 2.1 2.8e-37 129.1 2.1 1.3 1 0 0 1 1 1 1 Amidohydrolase SF3b1 PF08920.10 GAK63899.1 - 2.7e-20 73.0 2.9 2.7e-20 73.0 2.9 3.0 2 1 1 3 3 3 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 GAK63899.1 - 4.4e-10 39.8 16.0 0.0012 19.2 0.1 8.6 6 2 4 10 10 10 3 HEAT repeats HEAT_EZ PF13513.6 GAK63899.1 - 1.8e-09 37.9 6.8 0.027 15.0 0.0 7.2 7 1 1 8 8 7 2 HEAT-like repeat Adaptin_N PF01602.20 GAK63899.1 - 9.1e-07 27.8 1.8 0.087 11.4 0.1 4.0 2 2 2 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 GAK63899.1 - 3.1e-05 24.5 0.4 2.3 8.9 0.0 4.9 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 GAK63899.1 - 4.6e-05 23.2 1.0 1.2 8.8 0.0 4.8 4 1 1 5 5 5 2 NUC173 domain HEAT PF02985.22 GAK63899.1 - 6.8e-05 22.8 11.7 1.2 9.6 0.1 8.5 11 0 0 11 11 10 1 HEAT repeat CLASP_N PF12348.8 GAK63899.1 - 9.3e-05 22.1 0.5 0.094 12.3 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 GAK63899.1 - 0.001 19.1 7.9 6.2 6.8 0.0 6.2 7 1 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 GAK63899.1 - 0.0012 18.7 6.3 0.48 10.3 0.1 5.1 6 2 0 6 6 6 2 Domain of unknown function (DUF3385) UME PF08064.13 GAK63899.1 - 0.0033 17.3 0.2 1.3 9.0 0.0 4.6 4 3 2 6 6 6 1 UME (NUC010) domain MMS19_C PF12460.8 GAK63899.1 - 0.0051 16.0 0.0 2.9 6.9 0.0 3.8 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 GAK63899.1 - 0.0056 15.8 2.0 0.076 12.1 0.0 3.1 3 0 0 3 3 3 1 Dopey, N-terminal LIDHydrolase PF10230.9 GAK63899.1 - 0.02 14.4 0.2 0.23 11.0 0.1 2.4 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF1428 PF07237.11 GAK63899.1 - 0.062 13.6 0.1 0.26 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) N1221 PF07923.13 GAK63899.1 - 0.086 12.0 1.7 5.3 6.1 0.0 3.3 3 0 0 3 3 3 0 N1221-like protein MOZ_SAS PF01853.18 GAK63900.1 - 2.6e-81 271.6 0.3 3.9e-81 271.0 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAK63900.1 - 7.7e-24 83.1 1.3 1.6e-23 82.0 1.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAK63900.1 - 1.5e-23 82.4 0.0 3.2e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 GAK63900.1 - 0.0058 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK63900.1 - 0.056 13.7 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.6 GAK63900.1 - 0.26 12.2 1.4 1.3 10.1 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Hva1_TUDOR PF11160.8 GAK63901.1 - 2.4e-15 56.4 5.4 3.3e-15 56.0 5.4 1.2 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain ProQ_C PF17516.2 GAK63901.1 - 0.1 12.0 0.0 0.3 10.5 0.0 1.8 1 1 1 2 2 2 0 ProQ C-terminal domain SIR2 PF02146.17 GAK63902.1 - 9.7e-32 110.3 0.0 1.7e-30 106.2 0.0 2.1 1 1 0 1 1 1 1 Sir2 family Na_Ca_ex PF01699.24 GAK63903.1 - 2.8e-31 108.5 23.6 5.6e-16 58.8 3.7 2.9 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Velvet PF11754.8 GAK63903.1 - 0.046 13.6 0.6 0.093 12.7 0.1 1.6 2 0 0 2 2 2 0 Velvet factor MscL PF01741.18 GAK63903.1 - 0.15 12.3 0.6 0.34 11.2 0.6 1.6 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Saf_2TM PF18303.1 GAK63903.1 - 1.3 8.6 6.0 0.2 11.2 1.0 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Ribosomal_S8e PF01201.22 GAK63905.1 - 6.8e-47 159.1 2.1 1.5e-46 158.0 2.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Red1 PF07964.11 GAK63905.1 - 0.63 8.2 6.0 0.71 8.0 6.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Macoilin PF09726.9 GAK63905.1 - 6.9 5.1 10.5 9.1 4.7 10.5 1.0 1 0 0 1 1 1 0 Macoilin family Yip1 PF04893.17 GAK63906.1 - 1.7e-09 37.6 11.7 3.3e-09 36.7 11.7 1.5 1 0 0 1 1 1 1 Yip1 domain DUF2428 PF10350.9 GAK63907.1 - 6.7e-65 219.1 0.0 1.4e-64 218.1 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) PIGA PF08288.12 GAK63907.1 - 1.6e-41 140.8 0.0 6.1e-41 138.9 0.2 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 GAK63907.1 - 4.5e-26 91.9 4.1 7.4e-26 91.2 0.6 2.9 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 GAK63907.1 - 6.9e-23 81.0 0.0 1.3e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAK63907.1 - 1.4e-20 74.1 0.0 4.4e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAK63907.1 - 1.4e-11 45.1 0.0 1.4e-11 45.1 0.0 6.3 8 1 0 8 8 8 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAK63907.1 - 0.00019 21.7 0.0 0.00065 20.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 HEAT PF02985.22 GAK63907.1 - 0.00065 19.7 8.9 2.8 8.4 0.1 5.7 5 0 0 5 5 5 2 HEAT repeat RVT_N PF13655.6 GAK63907.1 - 0.096 13.0 0.1 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase HEAT_2 PF13646.6 GAK63907.1 - 0.75 10.2 10.7 0.73 10.3 0.5 5.2 4 0 0 4 4 4 0 HEAT repeats RMI1_N PF08585.12 GAK63908.1 - 1.9e-47 161.9 0.0 2.5e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein tRNA-synt_2c PF01411.19 GAK63909.1 - 4e-214 712.2 0.0 5.4e-214 711.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAK63909.1 - 3.9e-17 62.1 0.2 9.3e-17 60.9 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAK63909.1 - 4.6e-11 43.3 11.5 3.1e-10 40.6 11.5 2.3 1 1 0 1 1 1 1 DHHA1 domain DUF3504 PF12012.8 GAK63910.1 - 0.67 9.8 4.4 1.4 8.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Spt20 PF12090.8 GAK63910.1 - 5.2 6.6 23.6 0.032 13.9 9.9 2.3 2 0 0 2 2 2 0 Spt20 family DUF3464 PF11947.8 GAK63910.1 - 6.5 6.5 6.7 20 4.9 6.7 1.9 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PP2C PF00481.21 GAK63911.1 - 2.8e-55 187.7 0.6 7.3e-55 186.4 0.1 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 GAK63911.1 - 1.5e-47 159.2 60.4 4.8e-08 32.6 1.0 9.6 7 1 2 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 GAK63911.1 - 4.9e-37 125.3 76.5 4.6e-06 26.9 0.9 13.3 6 2 12 18 18 18 17 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 GAK63911.1 - 2.2e-25 89.3 0.0 6.4e-25 87.8 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 GAK63911.1 - 2.3e-07 30.5 25.7 0.012 15.1 0.5 5.6 2 1 4 6 6 6 6 Leucine-rich repeat LRR_5 PF13306.6 GAK63911.1 - 0.00017 21.6 0.4 9.7 6.2 0.1 4.4 3 1 1 4 4 4 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 GAK63911.1 - 0.049 14.2 47.8 2.9 8.8 0.0 14.8 17 0 0 17 17 17 0 Leucine Rich Repeat LRR_6 PF13516.6 GAK63911.1 - 0.073 13.2 54.1 9 6.6 0.4 13.7 13 0 0 13 13 13 0 Leucine Rich repeat PRA1 PF03208.19 GAK63912.1 - 1.5e-32 112.2 0.9 1.8e-32 111.9 0.9 1.0 1 0 0 1 1 1 1 PRA1 family protein Tetraspanin PF00335.20 GAK63912.1 - 2 8.1 6.1 3 7.5 6.1 1.3 1 0 0 1 1 1 0 Tetraspanin family FAD_binding_3 PF01494.19 GAK63913.1 - 3.8e-23 82.3 0.0 1.1e-22 80.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAK63913.1 - 2.2e-05 23.9 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAK63913.1 - 5.2e-05 22.3 0.8 0.0022 16.9 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 GAK63913.1 - 0.00014 22.0 1.3 0.00041 20.5 1.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAK63913.1 - 0.00034 21.1 0.3 0.0012 19.4 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAK63913.1 - 0.00044 20.3 0.0 0.00086 19.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAK63913.1 - 0.0029 16.7 2.2 0.0049 16.0 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAK63913.1 - 0.0037 16.9 2.8 0.0095 15.5 2.5 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAK63913.1 - 0.0041 16.5 0.0 0.62 9.3 0.0 3.2 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAK63913.1 - 0.061 12.0 0.8 0.093 11.4 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein SE PF08491.10 GAK63913.1 - 0.066 12.2 0.0 3.7 6.5 0.0 2.4 2 1 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 GAK63913.1 - 0.17 10.9 1.2 0.26 10.3 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ig_mannosidase PF17753.1 GAK63914.1 - 1.6e-07 31.0 0.0 3.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 GAK63914.1 - 0.015 15.9 0.0 0.031 14.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 ubiquitin PF00240.23 GAK63915.1 - 2.9e-20 71.8 0.1 4.5e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 GAK63915.1 - 6.6e-20 70.6 8.0 3.7e-13 49.1 0.9 2.9 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 GAK63915.1 - 4.5e-15 55.1 6.7 8.5e-15 54.2 6.7 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 GAK63915.1 - 3.4e-05 23.6 0.4 5.3e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 GAK63915.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 GAK63915.1 - 0.019 14.8 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain SOG2 PF10428.9 GAK63915.1 - 0.056 12.6 7.0 0.083 12.1 7.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein UBA_3 PF09288.10 GAK63915.1 - 0.057 13.2 0.2 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 GAK63915.1 - 0.17 12.2 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 GAK63915.1 - 1.7 8.6 5.5 20 5.2 0.4 2.9 1 1 1 2 2 2 0 STI1 domain RAP1 PF07218.11 GAK63915.1 - 8.4 4.5 8.8 12 4.0 8.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tho1_MOS11_C PF18592.1 GAK63918.1 - 4.9e-12 45.5 3.0 4.9e-12 45.5 3.0 3.3 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain SAP PF02037.27 GAK63918.1 - 3.2e-11 42.7 0.2 7.9e-11 41.4 0.2 1.7 1 0 0 1 1 1 1 SAP domain Enkurin PF13864.6 GAK63918.1 - 0.14 12.6 6.0 0.83 10.1 3.3 2.3 2 0 0 2 2 2 0 Calmodulin-binding Muskelin_N PF06588.11 GAK63919.1 - 3.5e-53 180.5 0.2 1.1e-20 74.4 0.0 3.5 3 1 0 3 3 3 3 Muskelin N-terminus Kelch_3 PF13415.6 GAK63919.1 - 1.3e-17 63.6 7.1 1.5e-08 34.7 0.0 6.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAK63919.1 - 4e-16 58.6 1.9 0.0024 17.8 0.1 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 GAK63919.1 - 3.2e-14 52.7 7.7 4.8e-06 26.5 0.2 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAK63919.1 - 5.3e-14 51.9 3.2 0.0028 17.9 0.1 6.7 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 GAK63919.1 - 2.6e-10 39.7 3.1 0.00014 21.4 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GAK63919.1 - 0.00063 19.6 6.3 0.043 13.8 0.3 4.6 5 0 0 5 5 5 1 Kelch motif DUF2807 PF10988.8 GAK63920.1 - 0.32 10.7 2.7 0.73 9.6 2.7 1.5 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Glyco_hydro_30 PF02055.16 GAK63921.1 - 1.6e-20 73.4 0.3 2.3e-20 72.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 GAK63921.1 - 1.6e-11 44.0 0.3 2.7e-11 43.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 GAK63921.1 - 0.0012 18.5 0.0 0.086 12.4 0.0 2.2 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Phage_base_V PF04717.12 GAK63921.1 - 0.016 15.1 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector DUF2487 PF10673.9 GAK63921.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Cytochrom_c3_2 PF14537.6 GAK63922.1 - 2.9 8.4 16.6 3 8.4 2.9 2.3 2 0 0 2 2 2 0 Cytochrome c3 PPTA PF01239.22 GAK63923.1 - 3.1e-39 131.6 20.8 7.6e-09 35.0 3.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat CDP-OH_P_transf PF01066.21 GAK63924.1 - 1.6e-16 60.8 2.0 5.3e-15 55.9 0.8 2.7 2 0 0 2 2 2 2 CDP-alcohol phosphatidyltransferase ERO1 PF04137.15 GAK63925.1 - 2.2e-129 431.7 0.0 2.7e-129 431.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF3844 PF12955.7 GAK63927.1 - 2.2e-29 101.7 2.2 3.5e-29 101.0 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Pkinase PF00069.25 GAK63928.1 - 7.7e-39 133.6 0.0 8e-27 94.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63928.1 - 1.9e-23 83.1 0.0 2.7e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK63928.1 - 7.9e-07 28.2 0.2 1.5e-06 27.2 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase zf-HIT PF04438.16 GAK63929.1 - 2.1e-08 33.9 9.5 3.1e-08 33.4 9.5 1.3 1 0 0 1 1 1 1 HIT zinc finger TMV_coat PF00721.21 GAK63929.1 - 0.041 13.7 0.1 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Virus coat protein (TMV like) DEAD PF00270.29 GAK63930.1 - 4.6e-47 160.0 0.0 7.6e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK63930.1 - 4.8e-31 107.4 0.1 2e-30 105.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK63930.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SAPS PF04499.15 GAK63930.1 - 0.02 13.7 4.1 0.031 13.1 4.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 GAK63930.1 - 0.17 10.0 9.4 0.28 9.4 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAK63930.1 - 0.21 9.8 6.5 0.37 9.0 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 GAK63930.1 - 4.2 7.1 11.0 10 5.9 11.0 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ORC6 PF05460.13 GAK63930.1 - 6.2 6.0 9.9 9.5 5.4 9.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Myb_DNA-binding PF00249.31 GAK63931.1 - 1.4e-11 44.4 0.0 3.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 GAK63931.1 - 6.9e-10 39.1 0.0 2.1e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 GAK63931.1 - 1.7e-08 34.1 4.9 3e-08 33.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 GAK63931.1 - 1.8e-07 31.3 0.0 5.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DDHD PF02862.17 GAK63931.1 - 0.1 12.8 4.8 0.26 11.4 2.7 2.2 2 0 0 2 2 2 0 DDHD domain Roughex PF06020.11 GAK63931.1 - 2.1 7.3 12.7 4.7 6.2 12.7 1.5 1 0 0 1 1 1 0 Drosophila roughex protein FAM60A PF15396.6 GAK63931.1 - 2.4 8.1 5.1 6.3 6.8 5.1 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.8 GAK63931.1 - 3.7 6.2 13.0 4.9 5.8 9.2 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Spt20 PF12090.8 GAK63931.1 - 3.9 7.0 19.1 8.9 5.9 13.8 2.4 2 0 0 2 2 2 0 Spt20 family SAPS PF04499.15 GAK63931.1 - 4.9 5.8 11.8 0.4 9.4 5.7 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 GAK63931.1 - 6.1 7.1 23.9 1.4 9.3 16.5 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SpoIIIAH PF12685.7 GAK63931.1 - 9.5 6.0 15.4 1 9.1 6.4 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Ras PF00071.22 GAK63932.1 - 3.5e-53 179.5 0.0 4.5e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK63932.1 - 1.3e-29 102.9 0.0 2.1e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK63932.1 - 4.2e-10 39.4 0.0 8.8e-10 38.3 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK63932.1 - 5.8e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK63932.1 - 0.0012 18.4 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAK63932.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAK63932.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Methyltransf_16 PF10294.9 GAK63933.1 - 4.4e-38 130.7 0.0 7.1e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAK63933.1 - 0.0019 17.8 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAK63933.1 - 0.047 14.4 0.7 0.2 12.4 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain B12D PF06522.11 GAK63934.1 - 1e-05 25.2 0.0 4e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DASH_Dam1 PF08653.10 GAK63935.1 - 1.4e-20 72.8 0.1 2.3e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 Mucin PF01456.17 GAK63935.1 - 0.016 15.2 18.2 0.016 15.2 18.2 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein HTH_9 PF08221.11 GAK63935.1 - 0.13 12.4 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF3439 PF11921.8 GAK63935.1 - 1 9.3 19.0 2.5 8.1 19.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.11 GAK63935.1 - 1.3 8.9 14.1 0.34 10.8 9.9 2.0 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.12 GAK63935.1 - 3.4 5.5 6.2 4.7 5.1 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GF_recep_IV PF14843.6 GAK63936.1 - 0.11 12.3 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Growth factor receptor domain IV ALG11_N PF15924.5 GAK63937.1 - 1.1e-81 273.8 0.0 1.7e-81 273.3 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus EBP PF05241.12 GAK63937.1 - 4.8e-59 198.8 12.9 4.8e-59 198.8 12.9 1.7 2 0 0 2 2 2 1 Emopamil binding protein Glycos_transf_1 PF00534.20 GAK63937.1 - 1.7e-15 57.0 0.0 2.7e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAK63937.1 - 1.7e-09 37.9 1.3 4e-09 36.7 1.3 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAK63937.1 - 1.2e-05 25.7 0.0 3.7e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAK63937.1 - 0.0023 18.4 4.9 0.0023 18.4 4.9 2.7 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain 7tm_1 PF00001.21 GAK63937.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Mlh1_C PF16413.5 GAK63938.1 - 2.6e-78 263.1 0.0 4e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GAK63938.1 - 4.3e-31 107.1 0.0 7.4e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAK63938.1 - 1.3e-10 41.2 0.0 3.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAK63938.1 - 1.8e-07 31.7 0.0 3.4e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBFD_NFYB_HMF PF00808.23 GAK63939.1 - 5.8e-14 52.1 0.2 8.8e-14 51.5 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAK63939.1 - 1.4e-05 25.4 1.6 1.8e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 GAK63939.1 - 0.016 15.4 0.1 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 CENP-W protein Trypan_PARP PF05887.11 GAK63939.1 - 0.23 11.4 11.1 0.051 13.5 7.5 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RhoGEF PF00621.20 GAK63940.1 - 3.7e-16 59.9 0.0 7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Zn_clus PF00172.18 GAK63941.1 - 0.0019 18.3 7.6 0.0043 17.1 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 GAK63944.1 - 1.7e-35 122.9 0.0 2e-11 43.9 0.0 3.0 2 1 1 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK63944.1 - 1.4e-12 48.2 0.1 2.6e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAK63944.1 - 0.0082 16.8 0.7 32 5.2 0.0 3.7 2 1 0 2 2 2 2 Aspartyl protease POTRA_TamA_1 PF17243.2 GAK63944.1 - 0.061 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Oxysterol_BP PF01237.18 GAK63945.1 - 1.7e-135 451.7 0.0 3.6e-135 450.6 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein Put_Phosphatase PF06888.12 GAK63945.1 - 2.4e-51 174.4 0.0 4.2e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase Ank_3 PF13606.6 GAK63945.1 - 7.6e-17 59.7 0.4 8.8e-05 22.6 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 GAK63945.1 - 5.7e-15 55.7 1.2 1.6e-11 44.6 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAK63945.1 - 1.9e-12 47.0 0.2 0.0017 18.7 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAK63945.1 - 4.4e-11 42.8 2.8 0.00035 20.8 0.2 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.29 GAK63945.1 - 3.3e-10 40.4 0.1 6.9e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 GAK63945.1 - 4.2e-09 36.8 0.9 2.4e-05 24.8 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) HAD PF12710.7 GAK63945.1 - 2.8e-08 34.4 0.0 2.8e-08 34.4 0.0 2.5 3 0 0 3 3 2 1 haloacid dehalogenase-like hydrolase PH_11 PF15413.6 GAK63945.1 - 6.9e-07 29.7 0.1 4.1e-06 27.2 0.1 2.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAK63945.1 - 3.3e-06 27.3 0.1 9.7e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain HAD_2 PF13419.6 GAK63945.1 - 0.28 11.2 0.8 1.1 9.3 0.2 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 GAK63946.1 - 0.26 11.4 8.3 1.6 8.9 0.9 2.7 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM251 PF15190.6 GAK63947.1 - 0.054 13.4 0.9 0.075 13.0 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 251 Ribonuclease PF00545.20 GAK63948.1 - 3.7e-11 43.6 0.2 5.4e-10 39.9 0.2 2.2 1 1 0 1 1 1 1 ribonuclease DUF1774 PF08611.10 GAK63949.1 - 1.6 9.1 7.6 0.52 10.7 1.6 2.7 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1774) DUF1218 PF06749.12 GAK63949.1 - 9.6 6.8 10.7 5.4 7.6 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) ERCC4 PF02732.15 GAK63950.1 - 4.5e-16 59.4 0.0 7.5e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain zf-PARP PF00645.18 GAK63951.1 - 4.5e-23 81.9 0.0 6.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 GAK63951.1 - 6.2e-19 65.5 111.3 0.068 13.1 1.4 11.6 11 0 0 11 11 11 11 AT hook motif Peptidase_C97 PF05903.14 GAK63952.1 - 1e-21 77.4 0.0 2.2e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain GNAT_acetyltr_2 PF13718.6 GAK63953.1 - 2.4e-89 298.6 0.0 6.2e-89 297.3 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 GAK63953.1 - 2.5e-62 209.9 0.0 4.5e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 GAK63953.1 - 1.5e-59 201.5 7.6 1.1e-55 188.9 0.1 3.3 1 1 1 2 2 2 2 Possible tRNA binding domain DUF1726 PF08351.11 GAK63953.1 - 5.1e-29 100.1 0.0 1.4e-28 98.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 GAK63953.1 - 0.004 17.4 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 GAK63953.1 - 0.015 15.5 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK63953.1 - 0.046 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 GAK63953.1 - 0.12 12.2 0.5 0.41 10.4 0.0 2.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase UL42 PF17638.2 GAK63954.1 - 8 6.5 11.3 3 7.8 6.3 2.3 2 0 0 2 2 2 0 HCMV UL42 Methyltransf_7 PF03492.15 GAK63955.1 - 4.5e-10 39.3 0.1 6.9e-05 22.2 0.2 3.2 2 1 1 3 3 3 2 SAM dependent carboxyl methyltransferase DUF3670 PF12419.8 GAK63955.1 - 0.0078 16.1 0.2 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 SNF2 Helicase protein WhiA_N PF10298.9 GAK63955.1 - 0.23 11.5 0.4 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain cNMP_binding PF00027.29 GAK63956.1 - 1.2e-25 89.4 0.0 9e-15 54.5 0.0 5.6 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Glycos_transf_2 PF00535.26 GAK63956.1 - 6.3e-21 74.9 0.0 1.6e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Patatin PF01734.22 GAK63956.1 - 1.4e-15 58.0 8.1 1.8e-14 54.4 5.4 3.4 2 1 0 2 2 2 1 Patatin-like phospholipase Glyco_tranf_2_3 PF13641.6 GAK63956.1 - 1.4e-08 34.9 0.2 3.8e-07 30.2 0.1 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Peptidase_C1_2 PF03051.15 GAK63957.1 - 1.3e-143 479.0 0.0 3.7e-143 477.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 GAK63957.1 - 0.00054 20.1 0.8 0.68 10.0 0.0 2.7 2 1 0 2 2 2 2 Papain family cysteine protease Peptidase_C10 PF01640.17 GAK63957.1 - 0.07 13.4 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Peptidase C10 family 2-Hacid_dh_C PF02826.19 GAK63958.1 - 1.1e-52 178.0 0.0 2.2e-52 177.0 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAK63958.1 - 5.2e-33 113.5 0.0 7.9e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 GAK63958.1 - 0.0011 19.1 0.7 0.0025 17.9 0.1 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 GAK63958.1 - 0.0012 19.1 0.1 0.0034 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SNURF PF07192.11 GAK63961.1 - 0.049 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 SNURF/RPN4 protein SRP-alpha_N PF04086.13 GAK63963.1 - 1.3e-54 186.1 2.5 2.5e-54 185.2 2.5 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 GAK63963.1 - 3e-46 157.5 0.1 2e-45 154.9 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GAK63963.1 - 3.5e-09 36.8 0.0 1.2e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 GAK63963.1 - 2.3e-05 23.5 0.0 7.1e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PI3K_1B_p101 PF10486.9 GAK63963.1 - 0.0073 14.2 1.6 0.013 13.3 1.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AAA_24 PF13479.6 GAK63963.1 - 0.02 14.6 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 GAK63963.1 - 0.046 13.8 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 GAK63963.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.6 GAK63963.1 - 0.093 13.0 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 GAK63963.1 - 0.15 11.3 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase MMR_HSR1 PF01926.23 GAK63963.1 - 0.17 12.0 2.0 0.71 10.0 0.2 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAK63963.1 - 0.23 11.8 0.0 0.23 11.8 0.0 3.1 2 2 0 3 3 3 0 AAA ATPase domain NOA36 PF06524.12 GAK63963.1 - 1.3 8.2 10.8 2.3 7.4 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GAK63963.1 - 3.6 8.0 13.1 7.6 7.0 13.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ATP_bind_1 PF03029.17 GAK63964.1 - 2.3e-84 282.9 0.0 2.7e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 GAK63964.1 - 1.8e-05 24.6 0.0 0.00066 19.5 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 GAK63964.1 - 0.00065 20.1 0.2 0.017 15.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 GAK63964.1 - 0.00082 19.9 0.0 0.0018 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAK63964.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 GAK63964.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 GAK63964.1 - 0.0017 18.4 0.0 0.0019 18.2 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAK63964.1 - 0.0021 18.0 0.0 0.37 10.7 0.2 2.3 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAK63964.1 - 0.0036 17.0 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAK63964.1 - 0.005 17.3 0.0 0.068 13.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 GAK63964.1 - 0.0059 15.6 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 GAK63964.1 - 0.008 15.7 0.0 2.3 7.7 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 GAK63964.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GAK63964.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 GAK63964.1 - 0.012 15.6 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAK63964.1 - 0.016 15.5 0.0 0.047 14.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAK63964.1 - 0.018 15.5 0.0 0.077 13.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 GAK63964.1 - 0.023 14.6 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 GAK63964.1 - 0.029 14.7 0.1 0.53 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAK63964.1 - 0.034 13.7 0.1 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAK63964.1 - 0.035 14.2 0.0 0.09 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 GAK63964.1 - 0.055 13.0 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 GAK63964.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 GAK63964.1 - 0.08 12.8 0.2 4.5 7.1 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 GAK63964.1 - 0.093 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAK63964.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAK63964.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.7 GAK63964.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 GAK63964.1 - 0.13 11.9 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 GAK63964.1 - 0.2 11.3 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase CobU PF02283.16 GAK63964.1 - 0.23 11.0 0.1 0.57 9.7 0.1 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase zf-RING_2 PF13639.6 GAK63965.1 - 7.7e-12 45.4 4.0 1.2e-11 44.7 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAK63965.1 - 6.3e-10 38.6 2.0 6.3e-10 38.6 2.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 GAK63965.1 - 2e-07 30.9 0.0 6.9e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 GAK63965.1 - 1.8e-05 24.6 1.6 2.8e-05 24.0 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAK63965.1 - 6.3e-05 22.7 3.2 9.9e-05 22.1 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK63965.1 - 0.00042 20.1 1.3 0.00065 19.5 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK63965.1 - 0.001 19.0 8.8 0.0014 18.6 0.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAK63965.1 - 0.0016 18.7 5.0 0.0052 17.0 5.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAK63965.1 - 0.0017 18.1 2.4 0.003 17.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK63965.1 - 0.0054 16.6 3.9 0.0092 15.8 3.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAK63965.1 - 0.047 13.7 1.0 0.1 12.6 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAK63965.1 - 0.11 12.7 3.1 0.59 10.3 3.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAK63965.1 - 0.73 9.5 3.0 1.4 8.6 3.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Iso_dh PF00180.20 GAK63966.1 - 1.3e-113 379.8 0.0 1.5e-113 379.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cullin_binding PF03556.15 GAK63967.1 - 2.2e-34 118.5 1.9 3.9e-34 117.7 1.9 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 GAK63967.1 - 3.1e-07 30.1 0.1 6.8e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain TipAS PF07739.13 GAK63967.1 - 2.2 8.9 5.6 1.1 9.9 0.8 2.7 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Ribosomal_L5_C PF00673.21 GAK63968.1 - 4.1e-18 65.4 0.0 6.1e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAK63968.1 - 3.1e-06 27.4 0.9 0.00036 20.8 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L5 LSM PF01423.22 GAK63969.1 - 3.3e-19 68.4 0.8 4.2e-19 68.0 0.8 1.2 1 0 0 1 1 1 1 LSM domain Aldedh PF00171.22 GAK63970.1 - 1.6e-108 363.2 0.0 2e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NOG1_N PF17835.1 GAK63972.1 - 4.3e-48 163.3 0.1 4.3e-48 163.3 0.1 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 GAK63972.1 - 5.8e-27 93.4 4.0 1.5e-26 92.1 4.0 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 GAK63972.1 - 1.2e-26 92.3 0.1 2.4e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAK63972.1 - 5.1e-18 65.2 0.0 1.3e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK63972.1 - 3e-08 33.4 0.0 6.4e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 GAK63972.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 GAK63972.1 - 0.018 15.1 0.9 1.5 8.8 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Roc PF08477.13 GAK63972.1 - 0.098 12.9 0.0 0.51 10.6 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAK63972.1 - 0.1 12.5 0.0 1.1 9.1 0.0 2.8 2 1 0 2 2 2 0 RsgA GTPase DUF4683 PF15735.5 GAK63972.1 - 1.6 8.3 9.1 2.9 7.4 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Mito_carr PF00153.27 GAK63973.1 - 8e-54 179.6 7.8 9e-18 64.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KCH PF16944.5 GAK63974.1 - 3.8e-86 289.0 11.8 4.9e-86 288.6 11.8 1.1 1 0 0 1 1 1 1 Fungal potassium channel Cauli_VI PF01693.16 GAK63976.1 - 9.4e-11 41.8 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyoxalase PF00903.25 GAK63976.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Synthase_beta PF11421.8 GAK63977.1 - 8.5 7.2 8.8 1.2 9.9 1.9 3.2 2 0 0 2 2 2 0 ATP synthase F1 beta subunit WD40 PF00400.32 GAK63978.1 - 5.3e-39 131.5 18.1 1.1e-07 32.4 0.5 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK63978.1 - 3.9e-11 43.1 0.0 0.087 13.1 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK63978.1 - 1e-05 24.7 0.1 0.022 13.7 0.0 2.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAK63978.1 - 1.8e-05 24.2 0.0 0.21 10.8 0.0 3.0 3 0 0 3 3 3 3 WD40-like domain Cytochrom_D1 PF02239.16 GAK63978.1 - 5.4e-05 21.9 0.0 9.2e-05 21.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Frtz PF11768.8 GAK63978.1 - 0.0061 14.9 0.1 0.086 11.1 0.0 2.6 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz GTP_EFTU PF00009.27 GAK63979.1 - 8.8e-55 185.3 0.1 1.8e-54 184.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAK63979.1 - 4.1e-14 52.4 0.0 9.5e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAK63979.1 - 1.8e-08 34.4 0.0 6e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAK63979.1 - 0.00024 21.2 0.0 0.00062 19.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 GAK63979.1 - 0.0014 18.4 0.0 0.0053 16.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 GAK63979.1 - 0.0041 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 GAK63979.1 - 0.17 11.7 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Nop25 PF09805.9 GAK63979.1 - 0.49 10.9 12.3 1.7 9.1 4.2 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PPP4R2 PF09184.11 GAK63979.1 - 4.1 6.9 13.7 0.51 9.9 1.3 2.3 2 0 0 2 2 2 0 PPP4R2 XRN_M PF17846.1 GAK63979.1 - 5.8 5.7 9.4 0.51 9.2 4.2 1.7 2 0 0 2 2 2 0 Xrn1 helical domain ADH_zinc_N_2 PF13602.6 GAK63982.1 - 2.6e-09 38.2 0.0 7.5e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK63982.1 - 2.2e-06 27.5 0.3 4.4e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK63982.1 - 0.00094 19.2 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PriC PF07445.12 GAK63982.1 - 0.086 12.8 0.5 0.19 11.6 0.5 1.5 1 0 0 1 1 1 0 Primosomal replication protein priC RRM_1 PF00076.22 GAK63983.1 - 3.6e-16 58.7 0.0 7.7e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.11 GAK63984.1 - 4.8e-33 113.4 0.0 1.1e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.13 GAK63984.1 - 0.14 11.7 0.0 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Arm_3 PF16186.5 GAK63984.1 - 0.4 10.3 5.0 0.17 11.5 0.2 2.5 2 0 0 2 2 2 0 Atypical Arm repeat MCD_N PF17408.2 GAK63984.1 - 0.62 10.2 5.8 0.22 11.7 0.3 3.0 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain HEAT_2 PF13646.6 GAK63984.1 - 0.8 10.1 14.0 0.21 12.0 0.8 4.3 3 1 0 3 3 3 0 HEAT repeats Lipase_3 PF01764.25 GAK63985.1 - 0.0036 17.2 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 GAK63985.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAK63985.1 - 0.009 15.5 0.2 0.91 9.0 0.1 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAK63985.1 - 0.012 14.9 0.2 0.036 13.3 0.2 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAK63985.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 GAK63985.1 - 0.092 13.3 13.4 0.022 15.3 7.6 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family Cofilin_ADF PF00241.20 GAK63987.1 - 4.1e-20 71.8 0.0 4.5e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TraX PF05857.11 GAK63987.1 - 0.051 13.6 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 TraX protein ox_reductase_C PF08635.10 GAK63988.1 - 5.9e-77 256.1 0.1 8.7e-77 255.6 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 GAK63988.1 - 4.7e-28 98.4 0.0 8.1e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAK63988.1 - 0.009 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain RRM_1 PF00076.22 GAK63989.1 - 1.4e-22 79.2 0.0 2.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK63989.1 - 0.0056 16.8 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RPA_interact_C PF14768.6 GAK63990.1 - 0.017 15.7 0.2 0.028 15.0 0.2 1.3 1 0 0 1 1 1 0 Replication protein A interacting C-terminal OTU PF02338.19 GAK63991.1 - 5.2e-13 49.6 0.0 1.1e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease AT_hook PF02178.19 GAK63991.1 - 0.31 11.0 5.7 1.3 9.1 5.7 2.2 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.25 GAK63993.1 - 3.4e-39 134.8 0.0 1.9e-37 129.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK63993.1 - 6.3e-25 87.9 0.0 1.5e-24 86.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK63993.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAK63993.1 - 0.015 14.7 0.3 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAK63993.1 - 0.13 11.9 0.5 2.2 7.9 0.0 2.7 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 CCDC53 PF10152.9 GAK63993.1 - 0.51 10.8 1.8 1.3 9.5 1.8 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2203 PF09969.9 GAK63993.1 - 6.1 7.6 6.2 23 5.7 5.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DEADboxA PF12343.8 GAK63995.1 - 8.4 7.0 13.6 1.2 9.7 0.5 3.5 3 0 0 3 3 3 0 Cold shock protein DEAD box A Glyco_transf_20 PF00982.21 GAK63996.1 - 2.7e-153 511.1 0.0 3.6e-153 510.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAK63996.1 - 1.9e-19 69.8 0.0 3.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase OPA3 PF07047.12 GAK63997.1 - 7.3e-43 145.3 1.7 7.3e-43 145.3 1.7 1.5 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) DUF883 PF05957.13 GAK63998.1 - 0.019 15.5 3.3 0.053 14.1 3.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Adeno_VII PF03228.14 GAK63998.1 - 0.094 13.4 0.3 0.17 12.5 0.3 1.4 1 0 0 1 1 1 0 Adenoviral core protein VII Macoilin PF09726.9 GAK63998.1 - 2.4 6.6 9.6 3.1 6.2 9.6 1.1 1 0 0 1 1 1 0 Macoilin family NUDIX_2 PF13869.6 GAK63999.1 - 5e-42 143.6 0.0 6.8e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Cas_Csy1 PF09611.10 GAK63999.1 - 0.083 11.9 0.6 0.13 11.3 0.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) TBP PF00352.21 GAK64000.1 - 4.2e-66 218.9 0.2 2.4e-32 110.7 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 GAK64000.1 - 1.3e-05 25.2 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 GAK64000.1 - 0.11 12.3 0.1 0.62 9.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Ferric_reduct PF01794.19 GAK64001.1 - 1.3e-21 77.0 5.9 1.3e-21 77.0 5.9 3.4 4 0 0 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAK64001.1 - 7.3e-15 55.4 0.0 2.1e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAK64001.1 - 7.9e-15 54.9 0.0 2.2e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 GAK64001.1 - 3.4e-05 24.4 0.0 0.22 12.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain adh_short PF00106.25 GAK64002.1 - 2.3e-39 134.9 0.1 2.7e-39 134.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK64002.1 - 1.6e-29 103.2 0.0 1.9e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK64002.1 - 0.00016 21.7 0.2 0.00023 21.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAK64002.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF562 PF04763.12 GAK64002.1 - 0.0073 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF562) DUF1776 PF08643.10 GAK64002.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 GAK64002.1 - 0.15 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bap31 PF05529.12 GAK64003.1 - 6.7e-48 162.0 7.1 6.7e-48 162.0 7.1 1.3 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 GAK64003.1 - 3.4e-08 33.4 9.5 7.6e-08 32.2 9.6 1.5 1 1 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4446 PF14584.6 GAK64003.1 - 0.0031 17.5 1.5 0.0051 16.8 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) SE PF08491.10 GAK64005.1 - 7.7e-99 330.2 0.0 1.4e-98 329.4 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GAK64005.1 - 4.5e-12 45.9 0.0 8.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAK64005.1 - 1.7e-09 37.7 0.3 6e-06 26.1 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAK64005.1 - 4.5e-05 23.6 0.3 0.00011 22.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAK64005.1 - 0.0016 17.6 0.4 0.04 13.0 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 GAK64005.1 - 0.0041 16.8 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 GAK64005.1 - 0.0049 16.1 0.0 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 GAK64005.1 - 0.009 15.1 0.0 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAK64005.1 - 0.0095 15.2 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 GAK64005.1 - 0.03 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 GAK64005.1 - 0.057 14.0 0.1 0.15 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAK64005.1 - 0.082 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 GAK64005.1 - 0.096 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 GAK64005.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 GAK64005.1 - 0.17 10.5 0.0 0.44 9.2 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Oxidored_molyb PF00174.19 GAK64006.1 - 5.8e-43 146.5 0.0 9.2e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAK64006.1 - 8.5e-14 51.7 0.5 4.9e-13 49.3 0.5 2.0 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain PilA4 PF18682.1 GAK64006.1 - 0.14 12.6 0.1 0.44 11.0 0.1 1.9 1 0 0 1 1 1 0 Pilin A4 Bromo_TP PF07524.13 GAK64007.1 - 3.3e-12 46.2 0.1 9.6e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 GAK64007.1 - 0.0076 16.3 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 GAK64007.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 GAK64007.1 - 0.042 14.2 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 CENP-S protein FlxA PF14282.6 GAK64007.1 - 9.5 6.3 13.2 0.035 14.1 1.7 2.4 2 0 0 2 2 2 0 FlxA-like protein RRM_1 PF00076.22 GAK64008.1 - 2.5e-17 62.4 0.0 4.1e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLEU7 PF15760.5 GAK64008.1 - 0.24 10.9 2.2 0.38 10.2 2.2 1.3 1 0 0 1 1 1 0 Leukemia-associated protein 7 Complex1_LYR PF05347.15 GAK64009.1 - 6.3e-10 38.9 8.3 5.3e-09 36.0 5.5 2.2 2 0 0 2 2 2 2 Complex 1 protein (LYR family) tRNA_int_endo PF01974.17 GAK64010.1 - 2.6e-20 72.3 0.0 5.4e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 GAK64010.1 - 1.1e-05 24.9 0.0 0.00024 20.7 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Myc_N PF01056.18 GAK64010.1 - 0.048 13.6 0.8 0.084 12.8 0.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region WD40 PF00400.32 GAK64011.1 - 1.9e-15 57.0 7.1 0.0047 17.7 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64011.1 - 3.3e-12 46.5 0.1 1.6e-06 28.3 0.0 4.6 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAK64011.1 - 5.2e-05 23.1 0.4 0.042 13.8 0.2 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 GAK64011.1 - 6.3e-05 22.9 0.4 0.041 13.8 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF4666 PF15697.5 GAK64011.1 - 0.0061 17.2 0.1 0.027 15.2 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4666) Ge1_WD40 PF16529.5 GAK64011.1 - 0.024 13.6 0.0 7.6 5.4 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MT-A70 PF05063.14 GAK64012.1 - 3e-43 147.7 0.0 4e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Pkinase PF00069.25 GAK64013.1 - 1.8e-73 247.2 0.1 1.8e-73 247.2 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64013.1 - 4.5e-52 176.9 0.2 4.5e-52 176.9 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 GAK64013.1 - 9.2e-23 80.4 0.0 2.2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 GAK64013.1 - 6e-12 46.0 1.0 1.1e-11 45.1 1.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 GAK64013.1 - 2.1e-06 26.8 0.0 3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAK64013.1 - 4.4e-06 26.2 0.0 7.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 GAK64013.1 - 0.0017 18.8 1.6 0.042 14.3 1.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 GAK64013.1 - 0.005 15.8 0.2 0.0097 14.9 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAK64013.1 - 0.01 15.7 0.0 0.04 13.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family GW PF13457.6 GAK64013.1 - 0.11 13.1 0.0 0.37 11.4 0.0 1.9 1 0 0 1 1 1 0 GW (Gly-Tryp) dipeptide domain Kdo PF06293.14 GAK64013.1 - 0.18 11.1 0.1 0.41 10.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 GAK64013.1 - 0.2 11.5 0.4 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain CENP-U PF13097.6 GAK64014.1 - 0.5 10.3 3.8 0.73 9.8 2.5 1.9 3 0 0 3 3 3 0 CENP-A nucleosome associated complex (NAC) subunit Vps35 PF03635.17 GAK64015.1 - 0 1026.6 0.0 0 1025.9 0.0 1.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Totivirus_coat PF05518.11 GAK64015.1 - 0.3 9.1 16.0 0.53 8.3 16.0 1.4 1 0 0 1 1 1 0 Totivirus coat protein zf-primase PF09329.11 GAK64016.1 - 2e-11 43.5 2.2 4.2e-11 42.5 2.2 1.6 1 0 0 1 1 1 1 Primase zinc finger FAM27 PF15832.5 GAK64016.1 - 1 10.0 6.0 2.4 8.8 0.1 3.5 3 0 0 3 3 3 0 FAM27 D and E protein family 2OG-FeII_Oxy_2 PF13532.6 GAK64018.1 - 1.1e-13 51.9 0.0 2.4e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Antimicrobial14 PF08109.11 GAK64018.1 - 0.14 12.2 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Lactocin 705 family RINGv PF12906.7 GAK64019.1 - 5.8e-06 26.3 6.7 1.7e-05 24.9 6.7 1.7 1 1 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 GAK64019.1 - 0.072 12.9 1.4 0.14 11.9 1.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAK64019.1 - 1.1 9.6 6.3 2 8.8 6.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAK64019.1 - 1.3 9.0 4.4 2.1 8.3 4.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAK64019.1 - 1.4 9.1 3.5 3.1 8.1 3.5 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 GAK64019.1 - 2.1 8.7 11.2 6.9 7.1 11.2 1.8 1 1 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 GAK64019.1 - 2.8 8.1 7.0 4.8 7.3 7.0 1.3 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 GAK64019.1 - 3.4 7.4 7.1 0.22 11.2 1.7 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type SRP9-21 PF05486.12 GAK64020.1 - 2.4e-07 31.0 0.7 2.4e-07 31.0 0.7 3.6 3 1 0 3 3 3 1 Signal recognition particle 9 kDa protein (SRP9) Rib_recp_KP_reg PF05104.12 GAK64020.1 - 0.025 15.6 12.1 0.05 14.6 12.1 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Mito_carr PF00153.27 GAK64021.1 - 2e-61 203.9 3.9 7.5e-22 77.1 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Fucose_iso_C PF02952.17 GAK64021.1 - 0.095 12.4 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain Tmemb_14 PF03647.13 GAK64021.1 - 0.44 11.3 3.9 11 6.9 0.0 3.4 3 1 0 3 3 3 0 Transmembrane proteins 14C HMG_box PF00505.19 GAK64022.1 - 1.1e-23 83.4 1.1 1.9e-23 82.7 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAK64022.1 - 8.3e-18 64.8 1.5 1.9e-17 63.6 1.5 1.6 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 GAK64022.1 - 0.002 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 GAK64022.1 - 0.014 15.9 0.2 0.028 15.0 0.2 1.4 1 0 0 1 1 1 0 YABBY protein RR_TM4-6 PF06459.12 GAK64022.1 - 0.98 9.2 4.0 2.7 7.7 4.1 1.6 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 PS_Dcarbxylase PF02666.15 GAK64023.1 - 3.4e-46 157.3 0.0 4.8e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase NAPRTase_C PF17956.1 GAK64023.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain AAA_12 PF13087.6 GAK64024.1 - 3.6e-54 183.4 0.0 5.7e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAK64024.1 - 6.3e-42 144.2 0.2 2.1e-41 142.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAK64024.1 - 2.1e-14 54.1 0.0 1.2e-13 51.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAK64024.1 - 5.5e-12 45.8 0.0 1.3e-08 34.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 GAK64024.1 - 0.00046 20.0 0.0 10 5.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 GAK64024.1 - 0.0024 17.9 0.0 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAK64024.1 - 0.0048 16.5 0.2 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 GAK64024.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF4958 PF16319.5 GAK64024.1 - 0.032 12.2 0.0 0.048 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) AAA_22 PF13401.6 GAK64024.1 - 0.16 12.3 0.0 0.72 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAK64024.1 - 0.16 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 GAK64024.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain IATP PF04568.12 GAK64025.1 - 1.5e-13 51.0 1.3 1.7e-13 50.8 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP MOFRL PF05161.13 GAK64025.1 - 0.0016 18.6 0.1 0.0019 18.4 0.1 1.3 1 1 0 1 1 1 1 MOFRL family UPF0449 PF15136.6 GAK64025.1 - 0.0052 17.2 1.7 0.0066 16.9 1.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 Caudo_TAP PF02413.17 GAK64025.1 - 0.019 15.1 2.4 0.023 14.9 2.4 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF1366 PF07104.11 GAK64025.1 - 0.036 13.8 4.8 0.047 13.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) DUF2779 PF11074.8 GAK64025.1 - 0.063 13.8 0.2 0.069 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) OSTbeta PF15048.6 GAK64025.1 - 0.068 13.3 3.6 0.083 13.0 3.6 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4140 PF13600.6 GAK64025.1 - 0.16 12.4 4.1 0.11 13.0 3.0 1.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 GAK64025.1 - 0.4 9.7 7.2 0.46 9.5 7.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP_sub_h PF10775.9 GAK64026.1 - 5.1e-23 80.8 2.2 7.4e-23 80.3 2.2 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h eIF2_C PF09173.11 GAK64027.1 - 7.6e-37 125.4 0.2 2.3e-36 123.9 0.2 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GAK64027.1 - 1.8e-21 76.6 1.2 1.9e-20 73.3 1.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAK64027.1 - 2.1e-13 50.5 0.4 2.1e-13 50.5 0.4 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 GAK64027.1 - 0.00094 19.1 0.6 0.025 14.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAK64027.1 - 0.0045 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 GAK64027.1 - 0.012 15.6 0.8 0.055 13.5 0.1 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 GAK64027.1 - 0.099 12.7 0.2 0.24 11.4 0.2 1.9 1 1 0 1 1 1 0 Dynamin family muHD PF10291.9 GAK64028.1 - 1.7e-54 185.0 0.0 2.6e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 GAK64028.1 - 7.6e-08 32.5 0.0 7.6e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Mod_r PF07200.13 GAK64028.1 - 0.75 9.9 12.4 0.026 14.6 5.0 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.25 GAK64029.1 - 4e-67 226.4 0.0 5e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64029.1 - 2.8e-32 112.0 0.0 3.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAK64029.1 - 1.2e-05 24.5 0.1 1.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAK64029.1 - 0.00041 19.8 0.0 0.0011 18.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK64029.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAK64029.1 - 0.0066 15.8 0.0 0.041 13.2 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 GAK64029.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GAK64029.1 - 0.017 14.7 0.0 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Glyco_hydro_35 PF01301.19 GAK64030.1 - 3.2e-75 253.7 0.0 4.6e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 GAK64030.1 - 3.7e-51 172.5 3.6 3.4e-27 95.3 0.4 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 GAK64030.1 - 6.8e-12 45.6 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 Cellulase PF00150.18 GAK64030.1 - 3.8e-05 23.2 0.0 0.00058 19.4 0.0 2.6 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) LSM PF01423.22 GAK64031.1 - 2.8e-19 68.6 0.2 3.4e-19 68.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 GAK64031.1 - 1.7 9.3 15.9 3.3 8.3 15.9 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DNA_repr_REX1B PF14966.6 GAK64032.1 - 3.5e-10 40.4 3.2 6.3e-05 23.6 0.7 2.9 3 0 0 3 3 3 2 DNA repair REX1-B LEH PF07858.12 GAK64032.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain CENP-H PF05837.12 GAK64032.1 - 0.022 15.2 3.0 0.033 14.6 2.7 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) eIF-4B PF06273.11 GAK64032.1 - 0.024 13.7 1.6 0.025 13.7 0.3 1.5 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B FliT PF05400.13 GAK64032.1 - 7 7.5 9.2 9.6 7.1 2.3 2.5 1 1 1 2 2 2 0 Flagellar protein FliT S4 PF01479.25 GAK64033.1 - 4.9e-10 39.0 0.7 4.9e-10 39.0 0.7 2.7 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 GAK64033.1 - 7e-06 26.9 0.0 1.6e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 GAK64034.1 - 4.7e-42 142.0 4.8 4.9e-42 141.9 3.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3987 PF13148.6 GAK64034.1 - 0.1 11.6 0.6 0.14 11.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Mito_carr PF00153.27 GAK64035.1 - 5.7e-73 240.9 5.9 1.9e-24 85.4 0.0 4.6 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 GAK64035.1 - 0.022 13.9 1.3 6.7 5.8 0.1 3.4 1 1 2 3 3 3 0 Gammaproteobacterial serine protease Cpn60_TCP1 PF00118.24 GAK64036.1 - 6.2e-162 539.7 5.7 7.2e-162 539.4 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF89 PF01937.19 GAK64037.1 - 6.9e-110 367.3 0.0 8.5e-110 367.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Got1 PF04178.12 GAK64037.1 - 4.3e-30 104.4 12.6 7.2e-30 103.7 12.6 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 GAK64037.1 - 0.1 10.8 4.1 0.14 10.4 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RRM_1 PF00076.22 GAK64038.1 - 4.9e-74 244.1 3.6 7.6e-19 67.3 0.0 6.2 7 0 0 7 7 7 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAK64038.1 - 9.6e-09 35.0 0.0 0.22 11.4 0.0 5.1 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GAK64038.1 - 4.3e-07 29.6 0.0 0.045 13.3 0.0 4.2 4 2 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAK64038.1 - 0.00042 20.2 0.0 0.98 9.5 0.0 3.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.12 GAK64038.1 - 0.00047 20.3 0.0 1.1 9.5 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif 2 RRM_7 PF16367.5 GAK64038.1 - 0.00062 19.8 0.0 7 6.9 0.0 4.1 4 0 0 4 4 3 2 RNA recognition motif Limkain-b1 PF11608.8 GAK64038.1 - 0.021 14.9 0.4 0.31 11.1 0.0 3.2 4 0 0 4 4 4 0 Limkain b1 HTH_CodY PF08222.11 GAK64038.1 - 0.18 11.4 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain SURF2 PF05477.11 GAK64038.1 - 1.7 8.3 11.1 6 6.5 10.0 2.5 2 1 0 2 2 2 0 Surfeit locus protein 2 (SURF2) TMEM214 PF10151.9 GAK64038.1 - 2.5 6.5 5.0 5.6 5.3 5.0 1.5 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4632 PF15451.6 GAK64038.1 - 6.9 6.8 6.0 7.4 6.7 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Fez1 PF06818.15 GAK64039.1 - 0.00051 20.6 38.4 0.016 15.7 6.8 4.1 2 1 1 3 3 3 2 Fez1 DUF773 PF05600.12 GAK64039.1 - 0.0014 17.5 5.1 0.0019 17.0 0.2 2.3 2 0 0 2 2 2 1 CDK5 regulatory subunit-associated protein 3 TPR_MLP1_2 PF07926.12 GAK64039.1 - 0.0098 16.0 11.0 0.0098 16.0 11.0 4.4 3 2 1 4 4 4 1 TPR/MLP1/MLP2-like protein SHE3 PF17078.5 GAK64039.1 - 0.043 13.5 7.8 1.6 8.4 0.9 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Pox_A_type_inc PF04508.12 GAK64039.1 - 0.081 12.8 6.5 6.3 6.8 0.1 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 GAK64039.1 - 0.25 10.2 33.9 0.0049 15.8 9.7 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4201 PF13870.6 GAK64039.1 - 0.53 10.0 14.2 3.1 7.5 2.3 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) FAM76 PF16046.5 GAK64039.1 - 0.64 9.3 10.1 0.69 9.2 0.9 2.9 2 0 0 2 2 2 0 FAM76 protein Baculo_PEP_C PF04513.12 GAK64039.1 - 5.3 7.1 7.3 33 4.5 0.5 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 GAK64039.1 - 7.4 5.1 14.7 3.1 6.3 1.2 2.3 2 0 0 2 2 2 0 AAA domain ADIP PF11559.8 GAK64039.1 - 7.4 6.6 22.9 0.4 10.8 2.2 4.2 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 GAK64039.1 - 8.2 5.9 34.1 3.1 7.3 1.7 3.4 2 1 1 3 3 3 0 Intermediate filament protein GTP_EFTU PF00009.27 GAK64040.1 - 2.6e-29 102.1 5.7 7.5e-28 97.4 3.3 3.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAK64040.1 - 7.1e-25 87.2 0.8 1.7e-24 86.0 0.8 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GAK64040.1 - 8.8e-07 29.0 0.2 2.1e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK64040.1 - 0.00018 21.1 0.2 0.00085 18.9 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAK64040.1 - 0.0024 17.8 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAK64040.1 - 0.018 14.5 1.2 0.03 13.7 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IF2_N PF04760.15 GAK64040.1 - 0.046 13.6 0.3 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF3545 PF12065.8 GAK64040.1 - 0.38 10.8 3.6 1 9.4 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) AAA_23 PF13476.6 GAK64040.1 - 1.8 9.1 4.8 10 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Noc2 PF03715.13 GAK64041.1 - 6.5e-107 357.2 1.0 1e-106 356.5 1.0 1.3 1 0 0 1 1 1 1 Noc2p family ATPase PF06745.13 GAK64042.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC UCH PF00443.29 GAK64044.1 - 4.4e-44 150.9 0.0 5.9e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK64044.1 - 2.1e-11 44.0 6.5 3.1e-10 40.1 6.5 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAK64044.1 - 9.3e-08 31.7 0.0 2.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family S4 PF01479.25 GAK64045.1 - 1.3e-11 44.0 0.0 2.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 GAK64045.1 - 8.5e-11 42.6 0.4 1.5e-10 41.9 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Syntaxin_2 PF14523.6 GAK64046.1 - 4.1e-20 72.0 3.5 4.2e-19 68.8 1.3 2.5 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 GAK64046.1 - 1.9e-10 40.6 0.5 1.9e-10 40.6 0.5 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 GAK64046.1 - 0.00055 19.7 6.8 0.0014 18.3 0.1 2.4 2 0 0 2 2 2 1 Syntaxin Serine_rich PF08824.10 GAK64046.1 - 0.0047 17.0 3.0 0.23 11.4 2.9 2.2 2 0 0 2 2 2 1 Serine rich protein interaction domain WD40 PF00400.32 GAK64047.1 - 1.3e-06 29.0 6.5 0.00084 20.1 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 GAK64047.1 - 3.5 8.2 8.8 8.6 7.0 0.1 5.0 6 1 0 6 6 6 0 PQQ-like domain DUF4112 PF13430.6 GAK64048.1 - 2.1e-31 108.3 0.0 3.1e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Tyr_Deacylase PF02580.16 GAK64050.1 - 4.2e-47 160.3 0.0 2.8e-46 157.6 0.0 1.9 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase EphA2_TM PF14575.6 GAK64053.1 - 0.28 12.1 2.2 0.78 10.7 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 GAK64053.1 - 0.94 8.9 2.4 1.6 8.2 2.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.25 GAK64054.1 - 7.6e-67 225.5 0.0 1e-66 225.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64054.1 - 9.8e-29 100.4 0.0 2e-28 99.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAK64054.1 - 0.0018 17.7 0.2 0.0032 16.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAK64054.1 - 0.0077 15.2 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAK64054.1 - 0.0085 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Phage_sheath_1C PF17482.2 GAK64054.1 - 0.073 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain RIO1 PF01163.22 GAK64054.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CBF PF03914.17 GAK64055.1 - 3.1e-28 98.9 0.3 1e-27 97.2 0.3 1.9 1 0 0 1 1 1 1 CBF/Mak21 family SRP-alpha_N PF04086.13 GAK64056.1 - 5.2 6.9 35.3 0.65 9.9 12.5 2.9 3 0 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal TFIID_20kDa PF03847.13 GAK64057.1 - 6.5e-30 103.4 1.4 9.8e-30 102.9 1.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 GAK64057.1 - 0.021 14.9 0.0 0.021 14.9 0.0 2.8 3 0 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit PspB PF06667.12 GAK64057.1 - 0.12 12.5 0.8 0.6 10.2 0.8 2.3 1 0 0 1 1 1 0 Phage shock protein B Phage_TAC_11 PF11836.8 GAK64057.1 - 1.6 8.9 8.6 4.5 7.5 1.0 3.8 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 APG5 PF04106.12 GAK64058.1 - 1.2e-70 237.7 0.0 1.5e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Peptidase_M22 PF00814.25 GAK64059.1 - 2.2e-78 263.7 0.1 7.5e-56 189.8 0.0 2.0 2 0 0 2 2 2 2 Glycoprotease family CTU2 PF10288.9 GAK64060.1 - 2.9e-31 108.0 0.8 2.8e-29 101.6 0.0 2.7 2 0 0 2 2 2 2 Cytoplasmic tRNA 2-thiolation protein 2 Myb_DNA-binding PF00249.31 GAK64061.1 - 3.2e-17 62.4 0.0 6.7e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAK64061.1 - 7.7e-17 61.3 0.0 4.2e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 GAK64061.1 - 0.0038 17.2 0.0 0.79 9.8 0.0 2.8 3 0 0 3 3 3 1 SLIDE Dcc1 PF09724.9 GAK64061.1 - 0.76 9.0 4.6 1.4 8.1 4.6 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 MBOAT_2 PF13813.6 GAK64062.1 - 2.8e-14 53.1 7.6 3.2e-14 53.0 4.4 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RNA_pol_L_2 PF13656.6 GAK64063.1 - 1.1e-29 101.9 0.0 1.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAK64063.1 - 1e-11 44.1 0.0 1.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pex14_N PF04695.13 GAK64064.1 - 2.6e-25 89.9 0.3 2.6e-25 89.9 0.3 3.0 3 1 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CALCOCO1 PF07888.11 GAK64064.1 - 3.9e-05 22.7 5.4 5.5e-05 22.2 5.4 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 GAK64064.1 - 0.0019 17.8 4.7 0.0029 17.1 4.7 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF1664 PF07889.12 GAK64064.1 - 0.0036 17.3 2.8 0.0036 17.3 2.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) MIP-T3_C PF17749.1 GAK64064.1 - 0.011 15.7 2.4 0.56 10.2 1.1 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF3829 PF12889.7 GAK64064.1 - 0.015 14.8 1.1 0.034 13.6 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3584 PF12128.8 GAK64064.1 - 0.021 12.4 5.3 0.028 12.0 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 GAK64064.1 - 0.024 14.7 8.8 0.29 11.2 4.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 GAK64064.1 - 0.024 13.6 0.7 0.043 12.8 0.7 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Atg14 PF10186.9 GAK64064.1 - 0.032 13.3 3.0 0.049 12.7 3.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 GAK64064.1 - 0.033 14.2 0.9 0.057 13.5 0.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 GAK64064.1 - 0.033 13.5 2.4 0.055 12.8 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAK64064.1 - 0.038 12.9 7.6 0.058 12.3 7.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 GAK64064.1 - 0.042 14.3 7.1 0.074 13.5 7.1 1.3 1 0 0 1 1 1 0 Fez1 Matrilin_ccoil PF10393.9 GAK64064.1 - 0.063 13.2 0.3 0.57 10.1 0.2 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF948 PF06103.11 GAK64064.1 - 0.11 12.8 3.1 7.2 6.9 1.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2524 PF10732.9 GAK64064.1 - 0.12 12.7 0.6 0.22 11.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) LXG PF04740.12 GAK64064.1 - 0.14 11.9 3.3 0.45 10.2 2.4 1.9 1 1 1 2 2 2 0 LXG domain of WXG superfamily Spectrin PF00435.21 GAK64064.1 - 0.14 12.6 3.7 0.13 12.7 1.0 2.1 2 0 0 2 2 2 0 Spectrin repeat BshC PF10079.9 GAK64064.1 - 0.16 10.6 1.5 0.23 10.2 1.5 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC KxDL PF10241.9 GAK64064.1 - 0.17 12.2 2.3 0.29 11.4 0.7 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.12 GAK64064.1 - 0.19 11.7 5.4 0.57 10.2 5.3 1.8 1 1 0 1 1 1 0 Laminin Domain II Enkurin PF13864.6 GAK64064.1 - 0.2 12.1 2.3 0.24 11.9 0.6 1.9 1 1 1 2 2 2 0 Calmodulin-binding DUF2968 PF11180.8 GAK64064.1 - 0.22 11.1 6.4 0.62 9.7 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) SHE3 PF17078.5 GAK64064.1 - 0.24 11.1 5.1 0.41 10.3 5.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 FTA4 PF13093.6 GAK64064.1 - 0.27 11.1 6.7 0.77 9.6 6.7 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 EzrA PF06160.12 GAK64064.1 - 0.31 9.2 6.7 2.8 6.0 7.5 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA HemX PF04375.14 GAK64064.1 - 0.32 10.2 6.1 0.37 10.0 4.5 1.8 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase NPV_P10 PF05531.12 GAK64064.1 - 0.38 11.3 5.8 8 7.0 0.8 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ERM PF00769.19 GAK64064.1 - 0.39 10.5 11.3 3.6 7.3 11.3 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Sec20 PF03908.13 GAK64064.1 - 0.58 10.1 2.1 12 5.9 0.3 2.3 2 0 0 2 2 2 0 Sec20 Mod_r PF07200.13 GAK64064.1 - 0.61 10.2 6.9 2.7 8.1 6.9 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CdvA PF18822.1 GAK64064.1 - 0.73 9.7 5.5 2.7 7.9 1.0 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Mt_ATP-synt_D PF05873.12 GAK64064.1 - 0.84 9.5 3.9 3.2 7.6 1.1 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) THOC7 PF05615.13 GAK64064.1 - 0.87 9.9 6.0 0.38 11.0 2.9 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 DUF148 PF02520.17 GAK64064.1 - 0.92 9.6 4.9 1.6 8.9 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF3450 PF11932.8 GAK64064.1 - 0.97 8.7 6.2 1.8 7.8 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HALZ PF02183.18 GAK64064.1 - 1.5 9.1 7.5 0.97 9.7 0.6 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper APG6_N PF17675.1 GAK64064.1 - 1.5 9.4 12.2 2.4 8.7 6.6 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 GAK64064.1 - 1.5 9.5 9.2 1.3 9.7 0.5 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med9 PF07544.13 GAK64064.1 - 2.1 8.5 5.2 23 5.2 0.4 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.11 GAK64064.1 - 2.8 8.0 6.8 4.5 7.4 2.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-H PF05837.12 GAK64064.1 - 3.2 8.2 7.8 18 5.8 7.8 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 GAK64064.1 - 4.7 6.4 4.7 8.6 5.5 4.7 1.4 1 1 0 1 1 1 0 TMPIT-like protein BLOC1_2 PF10046.9 GAK64064.1 - 5.4 7.4 7.4 8.3 6.8 3.1 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BAR PF03114.18 GAK64065.1 - 1.1e-21 77.5 0.1 1.9e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 BAR domain CENP-B_dimeris PF09026.10 GAK64065.1 - 0.061 13.7 0.1 0.061 13.7 0.1 3.9 5 0 0 5 5 5 0 Centromere protein B dimerisation domain BAR_3 PF16746.5 GAK64065.1 - 0.083 12.6 2.3 0.13 11.9 2.3 1.2 1 0 0 1 1 1 0 BAR domain of APPL family DUF2203 PF09969.9 GAK64065.1 - 0.23 12.2 1.7 0.69 10.7 1.7 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) MMM1 PF10296.9 GAK64065.1 - 0.32 10.0 1.0 0.4 9.7 0.1 1.6 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 DUF3584 PF12128.8 GAK64065.1 - 0.43 8.0 5.3 0.63 7.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 GAK64065.1 - 4.7 7.7 14.6 0.076 13.5 6.1 2.3 3 0 0 3 3 3 0 Apg6 coiled-coil region LCAT PF02450.15 GAK64066.1 - 1.1e-07 31.3 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 GAK64066.1 - 8.5e-06 26.5 0.1 8.5e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK64066.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAK64066.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1748 PF08520.10 GAK64067.1 - 8e-26 89.7 0.0 9.1e-26 89.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Nup54 PF13874.6 GAK64068.1 - 1.4e-33 116.0 6.9 1.4e-33 116.0 6.9 3.0 2 2 1 3 3 3 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 GAK64068.1 - 0.0072 16.2 0.4 0.0072 16.2 0.4 2.8 3 0 0 3 3 3 1 Nup54 C-terminal interacting domain Atg14 PF10186.9 GAK64068.1 - 8.5 5.4 10.1 0.18 10.9 1.3 2.3 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lactonase PF10282.9 GAK64069.1 - 7.9e-72 242.4 0.6 1.2e-71 241.8 0.6 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Pheromone PF08015.11 GAK64070.1 - 0.96 10.5 7.0 36 5.5 0.1 2.8 2 0 0 2 2 2 0 Fungal mating-type pheromone Coprogen_oxidas PF01218.18 GAK64071.1 - 1.7e-123 411.1 0.0 4.4e-123 409.7 0.0 1.6 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Mg_trans_NIPA PF05653.14 GAK64072.1 - 1e-63 215.2 6.2 3.3e-60 203.7 5.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAK64072.1 - 0.00063 19.9 4.2 0.00063 19.9 4.2 3.4 3 1 0 3 3 3 1 EamA-like transporter family SPX PF03105.19 GAK64072.1 - 0.71 9.7 14.2 0.52 10.2 0.2 2.3 2 0 0 2 2 2 0 SPX domain CDC45 PF02724.14 GAK64072.1 - 5.3 5.2 6.5 2 6.6 0.5 2.0 2 0 0 2 2 2 0 CDC45-like protein Transgly_assoc PF04226.13 GAK64072.1 - 9.3 6.6 9.9 4.1 7.7 2.5 3.3 2 1 1 3 3 3 0 Transglycosylase associated protein zf-C2H2 PF00096.26 GAK64073.1 - 7.1e-06 26.2 18.4 0.00035 20.9 0.9 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK64073.1 - 9.6e-06 25.8 4.9 9.6e-06 25.8 4.9 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAK64073.1 - 0.022 15.6 13.8 0.15 12.9 1.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 GAK64073.1 - 0.42 11.1 7.7 2.3 8.7 2.4 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 GAK64073.1 - 1.9 8.9 7.4 23 5.4 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CUE PF02845.16 GAK64074.1 - 4.4e-10 39.1 0.0 7.5e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 GAK64074.1 - 0.045 13.9 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Rsm22 PF09243.10 GAK64074.1 - 0.1 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DSPc PF00782.20 GAK64075.1 - 3.8e-26 91.5 0.6 6.9e-26 90.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAK64075.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 GAK64075.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 GAK64075.1 - 0.043 14.1 0.2 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 GAK64075.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TPR_1 PF00515.28 GAK64077.1 - 3.2e-10 39.4 10.4 3.4e-06 26.6 1.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAK64077.1 - 2e-09 36.9 12.7 0.00016 21.5 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK64077.1 - 4.4e-08 33.1 2.8 4.4e-08 33.1 2.8 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAK64077.1 - 4.1e-06 27.0 2.1 4.1e-06 27.0 2.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAK64077.1 - 1.3e-05 24.8 6.4 6.2e-05 22.6 2.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 GAK64077.1 - 1.5e-05 25.1 5.5 0.019 15.3 0.7 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat NYD-SP12_N PF15015.6 GAK64077.1 - 1.5e-05 23.6 0.4 2e-05 23.2 0.4 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_16 PF13432.6 GAK64077.1 - 7.4e-05 23.3 7.7 0.0001 22.9 5.8 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAK64077.1 - 0.00012 22.5 8.9 0.00026 21.5 4.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAK64077.1 - 0.00042 19.6 2.4 0.31 10.2 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64077.1 - 0.00043 20.5 6.3 0.00056 20.1 4.6 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAK64077.1 - 0.00099 19.0 1.6 0.18 11.9 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAK64077.1 - 0.0012 18.8 4.5 0.1 12.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK64077.1 - 0.0031 18.2 4.7 0.075 13.9 1.9 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAK64077.1 - 0.0062 17.1 5.0 1.7 9.5 0.6 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAK64077.1 - 0.041 14.0 1.4 1.5 8.9 0.4 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) DUF5588 PF17826.1 GAK64077.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) TPR_10 PF13374.6 GAK64077.1 - 4.4 7.3 5.7 2.2 8.3 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Malic_M PF03949.15 GAK64078.1 - 4.9e-86 288.2 0.0 6.8e-86 287.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAK64078.1 - 9.3e-67 224.3 0.0 1.4e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SSFA2_C PF14723.6 GAK64078.1 - 0.028 14.3 0.1 0.028 14.3 0.1 1.8 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus RhoGEF PF00621.20 GAK64079.1 - 1e-18 68.3 0.0 1.9e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain SAP30_Sin3_bdg PF13867.6 GAK64080.1 - 0.00022 21.5 0.0 0.00064 20.0 0.0 1.8 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 GAK64081.1 - 4.3e-07 29.7 9.3 7.8e-07 28.9 9.3 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 GAK64081.1 - 0.00066 19.6 4.4 0.0013 18.6 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 GAK64081.1 - 0.013 15.7 0.7 0.03 14.6 0.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_2 PF03107.16 GAK64081.1 - 0.035 14.4 4.2 0.067 13.5 1.9 2.2 2 0 0 2 2 2 0 C1 domain WHIM1 PF15612.6 GAK64081.1 - 0.18 11.4 0.5 0.44 10.1 0.1 1.9 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 Caldesmon PF02029.15 GAK64081.1 - 0.23 10.2 55.9 0.35 9.6 55.9 1.2 1 0 0 1 1 1 0 Caldesmon Mitochondr_Som1 PF11093.8 GAK64083.1 - 5.9e-09 35.8 0.4 1e-08 35.1 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 ObR_Ig PF18589.1 GAK64083.1 - 0.047 14.1 0.1 0.084 13.3 0.1 1.3 1 0 0 1 1 1 0 Obesity receptor immunoglobulin like domain Alpha-amylase PF00128.24 GAK64084.1 - 3.8e-23 82.6 2.0 1.2e-18 67.8 0.4 2.6 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 GAK64084.1 - 3.5e-10 38.8 1.4 0.0028 15.9 0.0 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 GAK64084.1 - 3e-05 24.1 2.6 9.4e-05 22.5 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Alpha-amylase_C PF02806.18 GAK64084.1 - 0.0026 18.2 1.5 0.0045 17.4 0.4 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Phage_TTP_13 PF16463.5 GAK64085.1 - 0.17 11.4 0.2 19 4.8 0.0 2.2 2 0 0 2 2 2 0 Phage tail tube protein family RRM_1 PF00076.22 GAK64088.1 - 2.1e-38 130.0 0.0 1.1e-15 57.2 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAK64088.1 - 9.7e-07 28.6 0.0 0.1 12.4 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GAK64088.1 - 3.5e-05 23.4 0.0 0.0002 21.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAK64088.1 - 0.0011 18.9 0.0 1.7 8.7 0.0 3.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAK64088.1 - 0.0091 16.0 0.0 0.63 10.1 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 GAK64088.1 - 0.047 13.8 0.0 38 4.5 0.0 4.0 4 0 0 4 4 4 0 RNA recognition motif G_glu_transpept PF01019.21 GAK64089.1 - 8.8e-160 532.8 0.0 1.1e-159 532.5 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Prominin PF05478.11 GAK64090.1 - 0.014 13.4 0.7 0.018 13.1 0.7 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 GAK64090.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.25 GAK64090.1 - 0.032 13.9 1.4 0.034 13.8 0.5 1.4 2 0 0 2 2 2 0 Syntaxin HisKA PF00512.25 GAK64090.1 - 0.033 14.2 1.7 0.52 10.4 0.4 2.5 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain Syntaxin-6_N PF09177.11 GAK64090.1 - 0.07 13.7 0.6 0.43 11.2 0.3 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlgN PF05130.12 GAK64090.1 - 0.27 11.7 6.6 0.61 10.6 1.2 2.1 2 0 0 2 2 2 0 FlgN protein DASH_Dam1 PF08653.10 GAK64090.1 - 0.3 10.9 0.7 0.82 9.5 0.3 1.9 1 1 2 3 3 3 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 GAK64090.1 - 0.34 11.3 1.3 1 9.8 0.2 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 GAK64090.1 - 0.43 11.3 2.1 0.52 11.1 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0183 PF03676.14 GAK64091.1 - 1.9e-45 155.9 0.0 1.4e-14 54.2 0.0 4.3 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) zf-ANAPC11 PF12861.7 GAK64092.1 - 2.2e-32 111.0 11.0 2.9e-32 110.6 11.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAK64092.1 - 4.1e-20 71.8 14.5 5.8e-20 71.3 14.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAK64092.1 - 1.5e-07 31.6 17.0 1.9e-06 28.1 17.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAK64092.1 - 0.0011 18.8 12.4 0.0047 16.8 12.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK64092.1 - 0.0011 18.8 18.9 0.0016 18.3 15.1 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK64092.1 - 0.0029 17.4 13.4 0.061 13.2 13.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK64092.1 - 0.046 13.7 11.1 0.17 11.9 11.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 GAK64092.1 - 0.11 12.2 14.0 2.4 8.0 14.0 2.3 1 1 0 1 1 1 0 RING-like zinc finger Tax PF02959.16 GAK64092.1 - 0.11 11.9 0.8 0.14 11.6 0.8 1.1 1 0 0 1 1 1 0 HTLV Tax zf-RING_5 PF14634.6 GAK64092.1 - 0.2 11.6 14.5 1.2 9.2 14.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 GAK64092.1 - 0.29 11.3 9.1 0.14 12.3 7.2 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 GAK64092.1 - 0.42 10.5 15.8 2.1 8.2 11.7 2.4 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GAK64092.1 - 0.69 10.1 13.5 2.4 8.4 13.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Ish1 PF10281.9 GAK64093.1 - 1.8e-65 216.9 28.1 1.3e-12 47.8 0.2 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein LEM PF03020.15 GAK64093.1 - 0.00049 19.6 0.0 27 4.4 0.0 4.8 5 0 0 5 5 5 0 LEM domain GYF PF02213.16 GAK64093.1 - 0.015 15.0 0.6 0.81 9.4 0.1 2.4 1 1 1 2 2 2 0 GYF domain SAP PF02037.27 GAK64093.1 - 0.043 13.6 0.0 47 3.9 0.0 4.2 5 0 0 5 5 5 0 SAP domain TryThrA_C PF12319.8 GAK64093.1 - 0.13 11.8 7.4 0.098 12.1 4.4 2.1 1 1 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal ApoLp-III PF07464.11 GAK64093.1 - 1.2 9.2 7.8 1.8 8.6 5.1 2.6 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) 6PGD PF00393.19 GAK64093.1 - 4.3 6.6 17.3 17 4.7 0.1 4.2 2 2 2 4 4 4 0 6-phosphogluconate dehydrogenase, C-terminal domain PIG-F PF06699.11 GAK64094.1 - 1.5e-12 48.1 2.0 2e-12 47.6 2.0 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Na_H_Exchanger PF00999.21 GAK64095.1 - 3.9e-68 230.0 17.9 5.1e-68 229.6 17.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 GAK64095.1 - 0.7 10.0 1.9 1 9.5 0.4 2.0 2 0 0 2 2 2 0 YrhC-like protein DUF2207 PF09972.9 GAK64095.1 - 1.7 7.3 0.0 1.7 7.3 0.0 2.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) DDE_3 PF13358.6 GAK64096.1 - 3.5e-25 88.5 0.0 5.6e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 GAK64096.1 - 3.7e-06 26.9 0.0 1.7e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 'Paired box' domain HTH_28 PF13518.6 GAK64096.1 - 0.0029 17.7 0.0 0.028 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain FtsK_gamma PF09397.10 GAK64096.1 - 0.013 15.3 0.0 0.048 13.5 0.0 2.0 1 0 0 1 1 1 0 Ftsk gamma domain MerR_1 PF13411.6 GAK64096.1 - 0.033 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein HAT_KAT11 PF08214.11 GAK64097.1 - 6e-31 108.0 0.0 1.4e-23 83.8 0.0 2.3 2 0 0 2 2 2 2 Histone acetylation protein Nt_Gln_amidase PF09764.9 GAK64098.1 - 1.4e-53 181.2 0.0 2.3e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal glutamine amidase DUF962 PF06127.11 GAK64099.1 - 9.7e-23 80.1 0.0 2.4e-22 78.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DER1 PF04511.15 GAK64100.1 - 7.9e-49 166.2 3.8 1e-48 165.8 3.8 1.1 1 0 0 1 1 1 1 Der1-like family PRP1_N PF06424.12 GAK64100.1 - 7.9e-46 156.1 4.8 7.9e-46 156.1 4.8 1.9 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 GAK64100.1 - 2.2e-22 77.8 40.9 0.037 14.9 0.1 13.5 7 6 6 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAK64100.1 - 3e-14 53.3 12.7 0.66 10.5 0.0 9.9 6 2 2 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAK64100.1 - 0.00028 20.8 2.3 4.7 7.6 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAK64100.1 - 0.00055 19.2 19.7 0.013 14.7 1.2 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAK64100.1 - 0.0058 16.8 5.6 1 9.6 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 GAK64100.1 - 0.021 14.8 0.1 48 3.8 0.0 4.4 5 1 0 5 5 5 0 Suppressor of forked protein (Suf) TPR_11 PF13414.6 GAK64100.1 - 0.027 14.1 0.1 0.17 11.6 0.1 2.5 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.6 GAK64100.1 - 0.034 14.8 44.1 0.11 13.2 2.9 8.7 6 3 4 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK64100.1 - 0.13 13.0 4.4 23 5.9 0.0 6.1 7 1 0 7 7 6 0 Tetratricopeptide repeat FAT PF02259.23 GAK64100.1 - 0.25 10.5 5.9 2.9 7.0 1.9 3.5 3 1 1 4 4 4 0 FAT domain HSF_DNA-bind PF00447.17 GAK64101.1 - 2.6e-20 72.8 0.0 4.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Xpo1 PF08389.12 GAK64103.1 - 3.9e-19 69.2 1.9 5.3e-16 59.0 0.0 4.7 6 0 0 6 6 6 1 Exportin 1-like protein Importin_rep_4 PF18808.1 GAK64103.1 - 0.02 15.2 1.3 0.063 13.6 0.1 2.4 3 0 0 3 3 3 0 Importin repeat HEAT PF02985.22 GAK64103.1 - 0.051 13.9 3.4 1 9.8 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Bac_DnaA PF00308.18 GAK64103.1 - 0.053 13.4 0.3 8 6.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein Thi4 PF01946.17 GAK64104.1 - 2e-102 341.4 0.4 2.3e-102 341.2 0.4 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAK64104.1 - 1.2e-08 35.0 1.9 3.7e-08 33.3 1.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAK64104.1 - 1e-07 32.1 0.2 2.9e-07 30.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAK64104.1 - 3.9e-07 29.5 0.4 4.2e-06 26.1 0.4 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAK64104.1 - 1.4e-06 27.7 1.3 2.8e-05 23.4 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GAK64104.1 - 4.4e-06 26.8 0.1 0.00029 20.8 0.1 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAK64104.1 - 4.5e-06 26.1 0.1 6.6e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK64104.1 - 0.00036 19.4 0.2 0.00054 18.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 GAK64104.1 - 0.006 15.7 0.0 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAK64104.1 - 0.0065 15.4 0.1 0.0095 14.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 GAK64104.1 - 0.016 14.5 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAK64104.1 - 0.025 13.9 1.3 0.032 13.6 1.3 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAK64104.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Mqo PF06039.15 GAK64104.1 - 0.14 10.7 0.0 0.26 9.8 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) DUF4387 PF14330.6 GAK64104.1 - 0.16 12.7 0.0 0.54 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4387) K_oxygenase PF13434.6 GAK64104.1 - 0.16 11.0 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Ribosomal_L6e PF01159.19 GAK64106.1 - 1.5e-38 131.7 0.9 1.5e-38 131.7 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Phosphoesterase PF04185.14 GAK64106.1 - 0.068 12.4 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoesterase family Ribosomal_L6e_N PF03868.15 GAK64106.1 - 0.094 13.0 0.8 0.094 13.0 0.8 2.8 3 0 0 3 3 3 0 Ribosomal protein L6, N-terminal domain Pet127 PF08634.10 GAK64107.1 - 1.1e-104 349.8 0.3 1.6e-104 349.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Prothymosin PF03247.14 GAK64110.1 - 0.15 12.5 62.1 0.06 13.8 44.9 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Las1 PF04031.13 GAK64111.1 - 1.8e-45 154.8 4.0 3.7e-45 153.8 1.3 2.2 2 0 0 2 2 2 1 Las1-like DUF4611 PF15387.6 GAK64111.1 - 0.1 12.8 0.2 22 5.3 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HTH_1 PF00126.27 GAK64111.1 - 0.14 12.1 1.4 0.6 10.1 1.4 2.1 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DnaJ-X PF14308.6 GAK64112.1 - 1.5e-48 165.0 3.1 1.5e-48 165.0 3.1 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAK64112.1 - 7.1e-25 86.9 0.9 2.3e-24 85.3 0.9 2.0 1 0 0 1 1 1 1 DnaJ domain SelP_N PF04592.14 GAK64112.1 - 0.0018 17.7 13.7 0.0018 17.7 13.7 2.0 3 0 0 3 3 3 1 Selenoprotein P, N terminal region OmdA PF13376.6 GAK64112.1 - 0.14 12.2 3.0 0.66 10.0 3.0 2.2 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated SSP160 PF06933.11 GAK64112.1 - 5.3 5.1 23.0 12 4.0 23.0 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UCH PF00443.29 GAK64113.1 - 7.3e-41 140.4 0.0 1.7e-40 139.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK64113.1 - 1.9e-07 31.0 0.0 6.7e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pantoate_ligase PF02569.15 GAK64113.1 - 0.018 14.3 0.4 0.032 13.4 0.4 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Forkhead PF00250.18 GAK64114.1 - 1.7e-10 41.0 0.1 3.3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain EPL1 PF10513.9 GAK64114.1 - 3.5 8.0 25.7 2.5 8.5 9.8 3.7 3 0 0 3 3 3 0 Enhancer of polycomb-like CTP_transf_1 PF01148.20 GAK64117.1 - 5.8e-70 236.1 16.8 5.6e-65 219.7 8.9 2.2 2 0 0 2 2 2 2 Cytidylyltransferase family DUF5345 PF17280.2 GAK64117.1 - 7.4 6.6 5.6 1.2 9.2 0.2 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5345) Pkinase PF00069.25 GAK64118.1 - 1.7e-64 217.8 0.0 2.2e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64118.1 - 2.4e-44 151.6 0.0 3.6e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK64118.1 - 2.2e-09 36.6 0.0 2.2e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAK64118.1 - 1.4e-06 27.9 0.0 4.9e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAK64118.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 GAK64118.1 - 0.25 10.2 0.6 1.9 7.3 0.0 2.4 2 1 0 2 2 2 0 Haspin like kinase domain T2SSF PF00482.23 GAK64120.1 - 0.09 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Peptidase_C15 PF01470.17 GAK64121.1 - 6.4e-09 36.3 0.0 0.0042 17.3 0.0 2.7 3 1 0 3 3 3 2 Pyroglutamyl peptidase CBF PF03914.17 GAK64122.1 - 8.4e-52 175.6 5.1 9.1e-52 175.5 0.0 3.3 4 0 0 4 4 4 1 CBF/Mak21 family Adaptin_N PF01602.20 GAK64122.1 - 0.0091 14.6 0.2 0.67 8.4 0.0 2.8 3 1 0 3 3 3 1 Adaptin N terminal region DUF4407 PF14362.6 GAK64122.1 - 7.5 5.8 15.2 20 4.4 15.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DPBB_1 PF03330.18 GAK64123.1 - 0.00016 21.9 0.0 0.00045 20.4 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase Macoilin PF09726.9 GAK64123.1 - 0.018 13.7 27.8 0.025 13.2 27.8 1.3 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 GAK64123.1 - 0.032 14.2 26.3 0.045 13.7 26.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 GAK64123.1 - 6.9 4.6 24.0 11 3.9 24.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.12 GAK64123.1 - 9.1 4.7 23.9 14 4.2 23.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CLASP_N PF12348.8 GAK64125.1 - 8.6e-26 90.9 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal ABC_membrane PF00664.23 GAK64126.1 - 1.9e-44 152.4 1.4 2.9e-44 151.8 1.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAK64126.1 - 4.6e-32 111.4 0.0 9e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.9 GAK64126.1 - 0.0023 16.8 0.0 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SMC_N PF02463.19 GAK64126.1 - 0.0034 16.9 0.0 0.058 12.8 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Glu-tRNAGln PF02686.15 GAK64126.1 - 0.15 12.4 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Zeta_toxin PF06414.12 GAK64126.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Zn_clus PF00172.18 GAK64128.1 - 1.9e-06 27.9 10.2 1.9e-06 27.9 10.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 GAK64128.1 - 0.0013 19.1 0.0 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF1610 PF07754.11 GAK64128.1 - 0.11 12.5 2.5 0.23 11.4 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF4148 PF13663.6 GAK64128.1 - 5.6 7.2 10.4 22 5.3 3.7 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PACT_coil_coil PF10495.9 GAK64129.1 - 1.4e-10 41.6 1.3 1.4e-10 41.6 1.3 6.0 6 0 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cep57_CLD_2 PF14197.6 GAK64129.1 - 0.0056 16.7 3.2 0.0056 16.7 3.2 11.6 7 3 4 11 11 11 3 Centrosome localisation domain of PPC89 DUF4140 PF13600.6 GAK64129.1 - 0.0074 16.7 6.5 0.0074 16.7 6.5 12.8 3 2 7 10 10 10 1 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 GAK64129.1 - 4.3 6.1 111.6 1.5 7.6 13.0 7.1 2 2 5 7 7 7 0 Spc7 kinetochore protein DDHD PF02862.17 GAK64130.1 - 2.1e-37 129.5 0.0 2.1e-37 129.5 0.0 2.9 3 1 0 3 3 3 1 DDHD domain Kri1_C PF12936.7 GAK64130.1 - 0.072 13.3 0.4 0.17 12.1 0.4 1.6 1 0 0 1 1 1 0 KRI1-like family C-terminal Aa_trans PF01490.18 GAK64132.1 - 3.8e-73 246.5 17.0 3.8e-73 246.5 17.0 1.6 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAK64132.1 - 0.00045 19.4 10.6 0.00045 19.4 10.6 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family NTP_transf_3 PF12804.7 GAK64133.1 - 2e-05 25.0 0.2 5.9e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 GAK64133.1 - 3.6e-05 23.3 3.6 0.0011 18.6 2.3 3.2 1 1 2 3 3 3 1 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 GAK64133.1 - 0.0028 15.9 0.4 0.004 15.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GAK64133.1 - 0.0084 15.8 4.7 0.34 10.7 4.7 2.5 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 GAK64133.1 - 0.0088 15.7 0.0 0.057 13.0 0.1 2.1 2 0 0 2 2 2 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 GAK64133.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Sec1 PF00995.23 GAK64134.1 - 2e-132 443.4 0.0 2.3e-132 443.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SRX PF09201.10 GAK64134.1 - 0.15 11.9 0.0 27 4.6 0.0 2.4 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit Hydrolase_6 PF13344.6 GAK64135.1 - 4.8e-08 33.0 0.0 9.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hexapep PF00132.24 GAK64135.1 - 1.4e-07 30.9 14.4 0.00055 19.6 3.5 5.3 4 1 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hydrolase_like PF13242.6 GAK64135.1 - 2.2e-06 27.6 0.0 7.9e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hexapep_2 PF14602.6 GAK64135.1 - 0.00014 21.5 10.1 0.018 14.8 1.8 4.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAK64135.1 - 0.05 12.5 0.1 0.077 11.9 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase Fungal_trans PF04082.18 GAK64136.1 - 8.3e-13 48.0 0.7 1.3e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK64136.1 - 2.1e-06 27.7 9.7 4.5e-06 26.7 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallothio_Euk PF12749.7 GAK64136.1 - 0.058 13.5 2.8 0.12 12.5 2.8 1.4 1 0 0 1 1 1 0 Eukaryotic metallothionein EamA PF00892.20 GAK64137.1 - 8.7e-27 94.0 32.7 3.2e-14 53.3 9.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 GAK64137.1 - 0.91 7.7 19.9 0.043 12.1 7.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) RseC_MucC PF04246.12 GAK64137.1 - 9.2 6.2 6.8 6.5 6.7 0.1 3.2 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC WD40 PF00400.32 GAK64138.1 - 9.5e-21 73.7 21.4 0.0005 20.8 0.4 7.0 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64138.1 - 4e-09 36.7 1.8 0.021 15.1 0.1 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK64138.1 - 0.00015 20.9 0.2 0.88 8.5 0.0 3.6 3 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 GAK64138.1 - 0.46 11.0 4.4 4.2 8.0 0.6 3.9 3 2 1 4 4 4 0 PQQ-like domain Pkinase PF00069.25 GAK64139.1 - 3e-70 236.6 0.0 4.4e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64139.1 - 3.6e-56 190.3 0.0 5.6e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 GAK64139.1 - 3.7e-10 40.0 0.0 7.5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 GAK64139.1 - 3.9e-07 29.9 6.9 3.9e-07 29.9 6.9 2.1 2 0 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CDC24 PF06395.11 GAK64139.1 - 0.00024 21.3 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin Kinase-like PF14531.6 GAK64139.1 - 0.0062 15.9 0.0 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAK64139.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 GAK64139.1 - 0.015 14.4 0.2 0.023 13.7 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAK64139.1 - 0.016 14.0 0.0 0.041 12.7 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase C1_2 PF03107.16 GAK64139.1 - 0.043 14.1 2.2 0.12 12.7 2.2 1.8 1 0 0 1 1 1 0 C1 domain CAMSAP_CH PF11971.8 GAK64139.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Prok-RING_1 PF14446.6 GAK64139.1 - 0.71 9.8 8.7 1.8 8.6 8.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TMEM154 PF15102.6 GAK64140.1 - 0.00054 19.9 0.2 0.00087 19.2 0.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF1218 PF06749.12 GAK64140.1 - 0.0012 19.3 2.1 0.0053 17.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) SCF PF02404.15 GAK64140.1 - 0.023 14.1 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor DUF2165 PF09933.9 GAK64140.1 - 0.073 13.1 0.2 0.073 13.1 0.2 1.8 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF2207 PF09972.9 GAK64140.1 - 0.09 11.5 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 GAK64140.1 - 0.13 13.2 0.0 0.43 11.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 GAK64140.1 - 0.35 10.8 1.6 0.92 9.5 1.6 1.7 1 0 0 1 1 1 0 Syndecan domain Sua5_yciO_yrdC PF01300.18 GAK64141.1 - 9e-48 162.1 0.0 4e-47 160.0 0.0 2.0 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 GAK64141.1 - 6.4e-33 114.2 0.0 1.2e-32 113.2 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding GST_N PF02798.20 GAK64142.1 - 9.7e-11 41.9 0.2 2.6e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAK64142.1 - 1e-10 41.7 0.0 2.7e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAK64142.1 - 7.4e-10 39.1 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK64142.1 - 9.3e-09 35.2 0.2 2.4e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAK64142.1 - 4.6e-07 30.0 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAK64142.1 - 4.8e-07 30.0 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 GAK64142.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_C_6 PF17171.4 GAK64142.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1242 PF06842.12 GAK64143.1 - 5e-18 64.6 0.8 8.4e-18 63.9 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) SQHop_cyclase_N PF13249.6 GAK64144.1 - 1.1e-54 185.5 0.9 3.3e-44 151.1 0.1 4.1 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 GAK64144.1 - 7.3e-50 169.9 5.3 2e-46 158.6 0.8 2.8 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 GAK64144.1 - 4.1e-35 119.2 5.6 1.1e-09 37.8 0.2 6.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 GAK64144.1 - 9.1e-08 31.5 0.5 4.6e-07 29.2 0.2 2.2 3 1 0 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 GAK64144.1 - 0.001 18.4 0.9 0.66 9.3 0.0 3.9 3 1 2 5 5 5 1 Pectic acid lyase DUF1925 PF09094.11 GAK64144.1 - 0.06 13.7 0.2 22 5.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) MPLKIP PF15502.6 GAK64145.1 - 0.095 12.9 2.4 0.33 11.2 2.4 2.2 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein FoP_duplication PF13865.6 GAK64145.1 - 4 8.1 21.4 7.4 7.2 21.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF155 PF02582.14 GAK64146.1 - 5.8e-50 169.8 0.9 9.1e-50 169.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF4611 PF15387.6 GAK64146.1 - 7.9 6.8 12.0 43 4.4 12.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Dus PF01207.17 GAK64147.1 - 4.7e-48 163.9 0.0 1.3e-33 116.4 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 GAK64147.1 - 0.018 14.9 8.4 0.034 14.0 1.0 2.7 2 1 0 2 2 2 0 CCCH-type zinc finger DUF3487 PF11990.8 GAK64147.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) zf_CCCH_4 PF18345.1 GAK64147.1 - 1.9 8.7 4.1 2.8 8.1 0.6 2.5 2 0 0 2 2 2 0 Zinc finger domain ATP-synt_C PF00137.21 GAK64148.1 - 1e-27 96.2 34.0 9.3e-16 57.9 13.8 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Insulin_TMD PF17870.1 GAK64148.1 - 7.9 6.6 6.8 1.7 8.8 0.7 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Oxidored_q2 PF00420.24 GAK64148.1 - 9.6 5.9 10.5 3.1 7.5 4.3 3.1 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ribosomal_L34 PF00468.17 GAK64149.1 - 1.1e-15 57.3 9.6 1.6e-15 56.8 9.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Aldedh PF00171.22 GAK64150.1 - 9.5e-15 54.0 6.2 1.5e-12 46.8 5.1 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family HSP70 PF00012.20 GAK64151.1 - 5.4e-162 540.1 0.6 8.1e-162 539.5 0.6 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAK64151.1 - 5.5e-12 45.1 0.0 1.4e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein zf-C3Hc3H PF13891.6 GAK64151.1 - 0.073 13.4 0.0 2.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Potential DNA-binding domain FAD_binding_7 PF03441.14 GAK64152.1 - 3e-53 180.3 2.7 4.5e-53 179.7 2.7 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAK64152.1 - 9.2e-21 74.5 0.0 2.5e-20 73.1 0.0 1.7 1 1 0 1 1 1 1 DNA photolyase Flavoprotein PF02441.19 GAK64153.1 - 2.7e-48 163.7 0.0 4.4e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein VPS9 PF02204.18 GAK64153.1 - 1.7e-26 92.4 0.0 3.1e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Phage_Nu1 PF07471.12 GAK64153.1 - 0.078 12.8 0.2 0.27 11.0 0.2 1.9 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 GATase_4 PF13230.6 GAK64154.1 - 1.1e-17 63.8 0.0 5.4e-17 61.6 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAK64154.1 - 6.4e-10 39.4 0.0 1.8e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pkinase PF00069.25 GAK64155.1 - 2.2e-27 96.1 0.0 1.4e-26 93.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64155.1 - 2.6e-12 46.6 0.0 4.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Cyclin PF08613.11 GAK64156.1 - 8.7e-08 32.7 0.0 8.7e-08 32.7 0.0 2.7 2 1 0 2 2 2 1 Cyclin DUF1192 PF06698.11 GAK64156.1 - 1.2 9.2 4.8 0.55 10.3 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) PNGaseA PF12222.8 GAK64157.1 - 5.8e-95 318.7 0.0 8.9e-95 318.1 0.0 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A COQ7 PF03232.13 GAK64157.1 - 3.8e-64 215.6 0.5 8.3e-64 214.5 0.4 1.6 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 FAD_binding_3 PF01494.19 GAK64157.1 - 2.8e-16 59.7 2.2 1.4e-08 34.4 0.1 3.4 4 0 0 4 4 4 2 FAD binding domain DAO PF01266.24 GAK64157.1 - 4.6e-05 23.2 0.3 0.0001 22.0 0.3 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 GAK64157.1 - 0.0028 16.7 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Ferritin PF00210.24 GAK64157.1 - 0.015 15.2 0.6 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Ferritin-like domain NAD_binding_9 PF13454.6 GAK64157.1 - 0.021 14.8 0.1 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAK64157.1 - 0.076 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK64157.1 - 0.095 13.3 0.1 0.42 11.2 0.1 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1684 PF07920.11 GAK64157.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) XPG_N PF00752.17 GAK64158.1 - 8.9e-35 119.2 0.0 1.8e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAK64158.1 - 1e-29 102.7 1.0 2.3e-29 101.6 0.0 2.1 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 GAK64158.1 - 6.8e-08 33.0 0.0 2.4e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAK64158.1 - 0.0071 16.9 0.0 0.024 15.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 GAK64158.1 - 0.049 13.5 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HHH_2 PF12826.7 GAK64158.1 - 0.08 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif TMF_DNA_bd PF12329.8 GAK64159.1 - 0.00013 21.9 4.6 0.00013 21.9 4.6 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 GAK64159.1 - 0.034 13.2 10.1 0.057 12.5 10.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HOOK PF05622.12 GAK64159.1 - 0.095 10.8 12.6 0.15 10.1 12.6 1.2 1 0 0 1 1 1 0 HOOK protein Tugs PF17840.1 GAK64159.1 - 0.11 12.7 1.6 0.49 10.6 1.6 2.1 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain LCD1 PF09798.9 GAK64159.1 - 0.37 9.2 11.6 1.9 6.9 0.0 2.4 2 1 0 2 2 2 0 DNA damage checkpoint protein DUF641 PF04859.12 GAK64159.1 - 0.94 9.8 10.4 0.022 15.1 3.4 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) PX PF00787.24 GAK64160.1 - 4.5e-26 91.1 0.1 6.4e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 PX domain SHE3 PF17078.5 GAK64161.1 - 2.2e-06 27.6 10.5 4.5e-06 26.5 4.5 3.1 2 1 0 2 2 2 1 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 GAK64161.1 - 0.031 14.4 1.3 0.031 14.4 1.3 4.3 4 0 0 4 4 4 0 TolA binding protein trimerisation Myosin_tail_1 PF01576.19 GAK64161.1 - 0.097 10.5 26.3 0.074 10.8 9.7 3.2 2 1 1 3 3 3 0 Myosin tail GAS PF13851.6 GAK64161.1 - 0.3 10.4 12.2 0.64 9.3 4.0 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding End3 PF12761.7 GAK64161.1 - 1.4 9.1 14.4 2.3 8.3 1.0 2.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Prominin PF05478.11 GAK64161.1 - 2.7 5.8 6.6 0.26 9.2 1.3 1.9 2 0 0 2 2 2 0 Prominin DUF4795 PF16043.5 GAK64161.1 - 3 7.4 9.5 1.5 8.4 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Bap31_Bap29_C PF18035.1 GAK64161.1 - 3.2 7.8 12.8 4.4 7.4 0.5 4.1 3 2 2 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF724 PF05266.14 GAK64161.1 - 4.4 7.1 11.3 1.4 8.7 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Filament PF00038.21 GAK64161.1 - 6.1 6.3 28.7 2.3 7.7 6.1 3.9 3 1 1 4 4 4 0 Intermediate filament protein COG2 PF06148.11 GAK64161.1 - 7.5 6.7 13.9 3.3 7.8 0.3 3.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 GAK64161.1 - 9 7.0 11.5 2 9.1 0.3 4.0 3 1 1 4 4 4 0 Initiation control protein YabA FAM76 PF16046.5 GAK64161.1 - 9 5.6 10.8 0.15 11.4 1.0 2.5 2 1 0 2 2 2 0 FAM76 protein Fez1 PF06818.15 GAK64161.1 - 9.1 6.7 23.3 5.8 7.3 11.2 3.2 3 1 1 4 4 4 0 Fez1 DAP3 PF10236.9 GAK64162.1 - 1.2e-71 241.5 2.2 1.5e-71 241.2 2.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 GAK64162.1 - 2.8e-08 34.4 0.4 2.8e-08 34.4 0.4 2.0 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 GAK64162.1 - 0.00045 20.2 0.3 0.005 16.8 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 GAK64162.1 - 0.0023 18.2 1.0 0.017 15.4 0.2 2.5 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 GAK64162.1 - 0.034 14.0 0.1 0.034 14.0 0.1 2.9 3 1 0 3 3 3 0 Helicase AAA_14 PF13173.6 GAK64162.1 - 0.039 14.0 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 GAK64163.1 - 8.1e-10 39.2 13.1 0.011 16.5 0.2 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64163.1 - 3.2e-07 30.6 0.1 0.0034 17.6 0.0 4.0 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 GAK64163.1 - 0.022 13.6 0.6 0.75 8.5 0.5 2.5 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pkinase PF00069.25 GAK64164.1 - 2e-44 152.0 0.0 1.3e-32 113.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64164.1 - 3.2e-17 62.7 0.0 1.2e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK64164.1 - 4e-05 23.7 0.2 4e-05 23.7 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAK64164.1 - 0.0011 18.3 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAK64164.1 - 0.0016 17.3 0.0 0.003 16.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAK64164.1 - 0.0038 16.6 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Oxidored_q6 PF01058.22 GAK64165.1 - 5.6e-21 74.7 0.1 9e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit V-SNARE_C PF12352.8 GAK64166.1 - 6.2e-16 58.4 0.4 1.6e-15 57.1 0.4 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAK64166.1 - 4.8e-06 26.4 0.0 1.4e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Sec20 PspA_IM30 PF04012.12 GAK64166.1 - 0.022 14.3 0.2 0.043 13.4 0.2 1.5 1 0 0 1 1 1 0 PspA/IM30 family Mito_fiss_reg PF05308.11 GAK64166.1 - 0.062 13.4 0.8 0.076 13.1 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Spc7 PF08317.11 GAK64166.1 - 0.098 11.5 0.5 0.22 10.3 0.3 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein FliD_N PF02465.18 GAK64166.1 - 0.92 10.3 5.2 1.7 9.4 3.1 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Methyltransf_25 PF13649.6 GAK64167.1 - 3.3e-11 43.7 0.0 6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK64167.1 - 4.6e-10 39.5 0.0 6.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAK64167.1 - 1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAK64167.1 - 6.7e-08 33.1 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK64167.1 - 1.3e-07 31.6 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK64167.1 - 6.6e-06 26.8 0.0 1.4e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAK64167.1 - 4.5e-05 22.5 0.0 6.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 GAK64167.1 - 0.00054 19.3 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAK64167.1 - 0.0013 18.3 0.3 0.0029 17.2 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GAK64167.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 GAK64167.1 - 0.12 13.4 0.0 0.29 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAK64167.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 GAK64167.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 GAK64167.1 - 0.16 11.7 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 GAK64167.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 zf-CCHC PF00098.23 GAK64168.1 - 2.1e-13 49.6 19.4 6.6e-05 22.8 1.2 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 GAK64168.1 - 2.4e-06 27.3 19.1 0.026 14.3 1.6 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_6 PF15288.6 GAK64168.1 - 0.021 14.6 0.6 0.021 14.6 0.6 3.7 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.6 GAK64168.1 - 0.027 14.2 19.5 0.12 12.2 0.4 4.3 4 0 0 4 4 4 0 Zinc knuckle SOBP PF15279.6 GAK64168.1 - 1.2 9.7 8.5 2.8 8.5 8.5 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein PHD_4 PF16866.5 GAK64168.1 - 4.3 7.5 9.1 5.3 7.2 1.6 3.2 2 1 1 3 3 3 0 PHD-finger zf-CCHC_3 PF13917.6 GAK64168.1 - 4.8 7.2 13.5 13 5.9 0.4 4.1 2 1 2 4 4 4 0 Zinc knuckle Sar8_2 PF03058.14 GAK64168.1 - 9.2 6.9 6.4 29 5.3 0.2 2.7 1 1 1 2 2 2 0 Sar8.2 family DER1 PF04511.15 GAK64169.1 - 8e-37 127.0 0.2 1e-36 126.7 0.2 1.1 1 0 0 1 1 1 1 Der1-like family DNA_pol_viral_N PF00242.17 GAK64169.1 - 4.9 6.5 7.0 7.9 5.9 7.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Peptidase_M20 PF01546.28 GAK64170.1 - 1.5e-33 116.2 0.1 2.5e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAK64170.1 - 6.7e-13 48.5 0.5 2.5e-12 46.7 0.5 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAK64170.1 - 0.016 14.9 0.1 0.042 13.5 0.1 1.6 1 1 0 1 1 1 0 Peptidase family M28 F-box-like PF12937.7 GAK64171.1 - 0.0024 17.7 2.1 0.017 15.0 2.1 2.5 1 1 0 1 1 1 1 F-box-like A_deamin PF02137.18 GAK64173.1 - 1.3e-41 143.2 0.0 5.8e-41 141.0 0.0 1.8 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Lactamase_B_2 PF12706.7 GAK64174.1 - 3.3e-31 108.4 0.0 6.2e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAK64174.1 - 2.5e-06 27.5 0.0 0.00036 20.5 0.0 3.2 3 1 0 3 3 3 1 Beta-lactamase superfamily domain adh_short PF00106.25 GAK64175.1 - 8.2e-48 162.5 0.2 1e-47 162.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK64175.1 - 6.3e-32 111.0 0.2 8.7e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK64175.1 - 3.9e-10 39.9 0.0 5.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAK64175.1 - 0.00025 20.5 0.0 0.00043 19.8 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAK64175.1 - 0.00027 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAK64175.1 - 0.011 15.3 0.0 0.029 13.8 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SIR2 PF02146.17 GAK64176.1 - 2.3e-53 180.7 0.0 3.9e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 Sir2 family AAA_33 PF13671.6 GAK64177.1 - 6.9e-12 45.7 0.3 2.6e-05 24.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain tRNA_lig_kinase PF08303.11 GAK64177.1 - 1.3e-06 28.6 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_22 PF13401.6 GAK64177.1 - 0.00025 21.3 0.1 0.00069 19.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAK64177.1 - 0.00087 19.8 0.1 0.0024 18.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 GAK64177.1 - 0.0099 15.8 0.0 0.035 13.9 0.0 1.8 1 1 1 2 2 2 1 Deoxynucleoside kinase AAA_16 PF13191.6 GAK64177.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 GAK64177.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4901 PF16244.5 GAK64177.1 - 0.049 13.0 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) T2SSE PF00437.20 GAK64177.1 - 0.056 12.5 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 GAK64177.1 - 0.19 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 GAK64177.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MRP-S28 PF10213.9 GAK64178.1 - 3e-39 134.3 0.1 4.8e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ammonium_transp PF00909.21 GAK64179.1 - 2.5e-112 375.5 29.9 2.9e-112 375.3 29.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TFIIS_M PF07500.14 GAK64180.1 - 1.6e-30 105.9 1.7 1.6e-30 105.9 1.7 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GAK64180.1 - 8.2e-19 67.2 8.9 1.3e-18 66.6 8.9 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GAK64180.1 - 4.3e-11 42.7 0.2 1.4e-10 41.1 0.2 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HTH_22 PF13309.6 GAK64180.1 - 0.064 13.3 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 HTH domain BASP1 PF05466.12 GAK64180.1 - 0.21 11.6 26.1 0.019 15.0 21.0 1.8 2 0 0 2 2 2 0 Brain acid soluble protein 1 (BASP1 protein) zinc_ribbon_4 PF13717.6 GAK64180.1 - 0.28 11.1 3.9 0.58 10.1 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain RAP1 PF07218.11 GAK64180.1 - 0.64 8.2 9.2 0.84 7.8 9.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3275 PF11679.8 GAK64180.1 - 0.8 9.7 7.0 1.7 8.6 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) zf-DNL PF05180.12 GAK64180.1 - 1.1 9.2 4.7 1.1 9.2 2.5 2.0 2 0 0 2 2 2 0 DNL zinc finger DUF1180 PF06679.12 GAK64180.1 - 5.8 7.3 8.6 3.8 7.9 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) WD40 PF00400.32 GAK64181.1 - 8.1e-40 134.1 12.5 2.5e-07 31.3 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Bromodomain PF00439.25 GAK64181.1 - 1.5e-21 76.2 0.1 2.7e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 GAK64181.1 - 0.0083 16.4 0.3 2.2 8.6 0.1 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK64181.1 - 0.034 12.8 0.1 5.8 5.4 0.0 2.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 GAK64181.1 - 0.049 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Nop14 PF04147.12 GAK64181.1 - 1.7 6.8 27.8 1.3 7.1 19.5 2.4 2 0 0 2 2 2 0 Nop14-like family PPP4R2 PF09184.11 GAK64181.1 - 4.9 6.7 22.7 0.11 12.1 9.9 2.5 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 GAK64181.1 - 6.2 5.0 20.7 3.3 5.9 12.9 2.4 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 GAK64181.1 - 8.5 6.6 31.5 1.7 8.9 14.2 3.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 FA_hydroxylase PF04116.13 GAK64182.1 - 3.3e-24 85.7 18.0 3.3e-24 85.7 18.0 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1708 PF08101.11 GAK64183.1 - 2.3e-21 76.5 0.2 7.6e-16 58.3 0.8 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 GAK64183.1 - 6.2e-07 29.4 0.0 3.4e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 RhoGAP domain Calpain_inhib PF00748.19 GAK64184.1 - 4.3 7.9 7.3 10 6.6 7.3 1.6 1 0 0 1 1 1 0 Calpain inhibitor KAR9 PF08580.10 GAK64184.1 - 4.6 5.7 6.7 7.6 4.9 6.7 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ribosomal_S10 PF00338.22 GAK64187.1 - 1.4e-24 86.2 0.0 3.1e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e BTB_2 PF02214.22 GAK64188.1 - 0.00029 21.1 0.0 0.028 14.7 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Longin PF13774.6 GAK64189.1 - 3.4e-25 87.9 0.0 5.1e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAK64189.1 - 5.4e-15 55.0 0.1 1.2e-14 53.8 0.1 1.6 1 1 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.12 GAK64189.1 - 0.083 12.9 1.3 0.11 12.5 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SLM4 PF16818.5 GAK64189.1 - 0.14 12.2 0.7 2.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Protein SLM4 DEAD PF00270.29 GAK64190.1 - 5e-13 49.2 0.0 8.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK64190.1 - 0.00037 20.8 0.0 0.00098 19.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aft1_HRA PF11786.8 GAK64191.1 - 0.0092 16.3 0.7 0.039 14.3 0.3 2.3 1 1 1 2 2 2 1 Aft1 HRA domain PLA2_B PF01735.18 GAK64192.1 - 3e-16 58.9 0.0 1.6e-12 46.6 0.1 3.0 3 0 0 3 3 3 3 Lysophospholipase catalytic domain ACPS PF01648.20 GAK64192.1 - 5.2e-14 52.3 0.4 2.3e-13 50.3 0.1 2.4 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily COX16 PF14138.6 GAK64193.1 - 6.5e-29 100.3 0.1 1.2e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.13 GAK64193.1 - 5.4e-27 94.2 0.1 2e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Erv1 / Alr family CcmH PF03918.14 GAK64193.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Mito_carr PF00153.27 GAK64194.1 - 2.6e-63 210.0 5.2 4.3e-22 77.9 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2347 PF09804.9 GAK64195.1 - 4.4e-41 141.3 0.0 6.2e-39 134.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 GAK64195.1 - 2.1 8.8 5.6 1.1 9.8 0.0 3.0 3 1 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PBP1_TM PF14812.6 GAK64196.1 - 0.015 15.7 1.3 0.027 14.8 1.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 GAK64196.1 - 0.09 13.0 5.8 0.07 13.4 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GAK64196.1 - 6.7 5.9 5.9 9.7 5.4 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Complex1_LYR_2 PF13233.6 GAK64197.1 - 1.8e-16 60.6 0.6 3.1e-16 59.9 0.6 1.4 1 0 0 1 1 1 1 Complex1_LYR-like HAUS6_N PF14661.6 GAK64197.1 - 0.21 11.2 1.8 0.28 10.7 1.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PALP PF00291.25 GAK64198.1 - 7.1e-53 179.9 6.0 1.2e-50 172.6 6.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ABC_trans_N PF14510.6 GAK64198.1 - 0.0048 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal UDPG_MGDP_dh_C PF03720.15 GAK64198.1 - 0.14 12.6 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Abhydrolase_6 PF12697.7 GAK64198.1 - 0.27 11.8 3.2 1.1 9.8 3.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF959 PF06121.14 GAK64198.1 - 1.6 8.9 8.6 8.6 6.6 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF959) TPR_1 PF00515.28 GAK64199.1 - 4.6e-36 121.2 20.6 5.4e-06 26.0 0.0 10.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAK64199.1 - 1.3e-32 109.3 21.7 0.00014 21.7 0.9 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAK64199.1 - 1.3e-25 87.4 18.2 0.00016 21.6 0.0 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAK64199.1 - 1e-17 64.1 14.5 0.013 15.8 0.4 7.8 5 3 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAK64199.1 - 5.1e-17 61.3 13.3 0.00021 20.9 0.1 7.6 5 1 2 7 7 7 4 TPR repeat TPR_16 PF13432.6 GAK64199.1 - 6.1e-17 62.0 22.6 0.0001 22.9 0.0 7.2 5 3 3 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAK64199.1 - 7.8e-16 57.2 7.3 0.014 15.8 0.1 9.5 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK64199.1 - 1e-12 47.7 20.0 0.75 10.8 0.1 10.6 6 4 6 12 12 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAK64199.1 - 2.1e-10 39.9 10.2 0.045 13.8 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK64199.1 - 1.1e-08 35.1 2.0 0.00053 20.1 0.0 5.4 3 3 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK64199.1 - 3.8e-08 33.7 25.9 0.00024 21.5 1.5 6.6 5 2 2 8 8 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64199.1 - 2.3e-07 31.0 14.4 0.088 13.0 0.6 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAK64199.1 - 3.4e-05 23.6 12.8 1.4 8.9 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAK64199.1 - 0.0001 21.8 1.9 0.0001 21.8 1.9 4.0 4 1 1 5 5 5 2 MalT-like TPR region SpoIIIAH PF12685.7 GAK64199.1 - 0.00058 19.8 1.9 0.00058 19.8 1.9 2.0 3 0 0 3 3 3 1 SpoIIIAH-like protein Methyltrans_RNA PF04452.14 GAK64199.1 - 0.054 12.8 1.8 0.2 11.0 0.2 2.3 2 0 0 2 2 2 0 RNA methyltransferase SHNi-TPR PF10516.9 GAK64199.1 - 0.15 11.5 10.0 9 5.8 0.5 5.3 6 0 0 6 6 6 0 SHNi-TPR Coatomer_E PF04733.14 GAK64199.1 - 0.17 11.3 6.2 3.5 6.9 0.2 3.7 2 1 0 3 3 3 0 Coatomer epsilon subunit Nuc_recep-AF1 PF11825.8 GAK64200.1 - 0.18 11.9 1.0 0.2 11.7 1.0 1.2 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Pardaxin PF07425.11 GAK64200.1 - 0.35 10.5 11.3 2.4 7.8 4.3 3.1 1 1 1 2 2 2 0 Pardaxin Antimicrobial_8 PF08103.11 GAK64200.1 - 1.4 9.2 4.8 4.5 7.6 0.4 3.0 1 1 2 3 3 3 0 Uperin family Rad60-SLD PF11976.8 GAK64201.1 - 5.1e-25 87.1 0.6 6.7e-25 86.7 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAK64201.1 - 6.5e-15 54.6 0.1 8.3e-15 54.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family LAG1-DNAbind PF09271.11 GAK64202.1 - 6.3e-37 127.5 0.0 2e-36 125.9 0.0 1.9 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 GAK64202.1 - 5e-14 52.8 0.0 1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF3545 PF12065.8 GAK64202.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Cu-oxidase_3 PF07732.15 GAK64203.1 - 4.4e-44 149.3 2.0 2.6e-43 146.8 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAK64203.1 - 1.5e-31 109.0 11.6 1.2e-25 89.8 1.5 4.1 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase PF00394.22 GAK64203.1 - 4.8e-27 95.0 0.0 1.2e-26 93.8 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Proteasome PF00227.26 GAK64204.1 - 2.6e-28 98.8 0.0 3.4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 GAK64204.1 - 0.0098 15.7 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family, helical bundle domain SF3A2 PF16835.5 GAK64205.1 - 2.8e-33 114.2 0.0 4.1e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GAK64205.1 - 1e-06 28.9 1.2 2.2e-06 27.9 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 GAK64205.1 - 0.019 14.5 0.6 0.039 13.5 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 GAK64205.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Syja_N PF02383.18 GAK64206.1 - 2.4e-78 263.7 0.0 3.5e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 GAK64207.1 - 5.7e-17 62.0 0.0 3.4e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HABP4_PAI-RBP1 PF04774.15 GAK64207.1 - 4.2 8.2 15.6 0.2 12.5 5.0 2.4 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Sigma70_ner PF04546.13 GAK64207.1 - 5.6 6.8 11.0 0.092 12.6 3.1 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2388 PF09498.10 GAK64208.1 - 0.0087 16.0 0.1 7.9 6.5 0.1 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2388) HSA PF07529.13 GAK64209.1 - 5.2e-13 49.1 3.7 5.2e-13 49.1 3.7 5.4 6 1 0 6 6 6 1 HSA Myb_DNA-bind_6 PF13921.6 GAK64209.1 - 7.5e-06 26.1 0.3 7.5e-06 26.1 0.3 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAK64209.1 - 0.0017 18.5 0.3 0.0048 17.1 0.3 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 GAK64209.1 - 0.0094 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Gti1_Pac2 PF09729.9 GAK64210.1 - 2.4e-60 203.7 0.0 5.9e-60 202.5 0.0 1.7 1 0 0 1 1 1 1 Gti1/Pac2 family Amino_oxidase PF01593.24 GAK64211.1 - 4.3e-53 181.2 0.6 5.4e-53 180.9 0.6 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK64211.1 - 2.6e-12 46.8 0.2 1e-11 44.9 0.2 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAK64211.1 - 1.1e-09 37.5 0.6 3.4e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 GAK64211.1 - 1.6e-08 34.1 0.1 2.9e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAK64211.1 - 4.1e-08 32.8 0.2 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK64211.1 - 5e-08 32.9 1.0 7.1e-07 29.1 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAK64211.1 - 3.2e-07 30.8 0.9 8e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAK64211.1 - 6.3e-07 29.1 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAK64211.1 - 2.4e-06 27.0 0.2 4.2e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 GAK64211.1 - 1.3e-05 24.7 1.1 0.00016 21.1 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAK64211.1 - 7.1e-05 22.0 2.3 0.001 18.2 0.1 2.6 2 1 1 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAK64211.1 - 0.00011 21.5 0.5 0.0072 15.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAK64211.1 - 0.00026 20.2 0.1 0.00026 20.2 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAK64211.1 - 0.0037 17.3 0.3 0.069 13.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAK64211.1 - 0.058 12.7 0.2 0.058 12.7 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Hexapep_2 PF14602.6 GAK64213.1 - 8e-12 44.7 6.2 1.4e-09 37.5 2.8 2.2 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 GAK64213.1 - 5.6e-11 41.7 6.4 8.1e-09 34.9 3.7 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 GAK64213.1 - 4.9e-09 36.3 0.3 9e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase DinB_2 PF12867.7 GAK64213.1 - 0.13 12.8 0.1 0.2 12.2 0.1 1.2 1 0 0 1 1 1 0 DinB superfamily tRNA-synt_1b PF00579.25 GAK64214.1 - 2.6e-62 210.8 0.0 6.8e-62 209.4 0.0 1.7 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) DUF913 PF06025.12 GAK64214.1 - 0.2 10.6 2.8 0.38 9.7 2.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MutS_V PF00488.21 GAK64215.1 - 4.6e-67 225.7 0.1 8.3e-67 224.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAK64215.1 - 8.1e-39 133.8 4.3 1.4e-38 133.1 4.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAK64215.1 - 3.8e-20 72.2 0.0 1.1e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 GAK64215.1 - 1.7e-08 34.8 0.0 4.4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 GAK64215.1 - 0.00052 19.7 0.0 0.0024 17.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAK64215.1 - 0.0029 18.2 0.1 0.027 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAK64215.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Carb_kinase PF01256.17 GAK64216.1 - 1.4e-48 165.5 0.0 5.4e-48 163.6 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate kinase DUF3337 PF11816.8 GAK64216.1 - 1.8e-48 164.7 0.0 2.8e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 GAK64216.1 - 2.1e-19 69.5 22.5 1.6e-05 25.6 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64216.1 - 0.00014 22.1 0.0 0.038 14.3 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK64216.1 - 0.048 12.3 0.3 13 4.3 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 EOS1 PF12326.8 GAK64217.1 - 1.9e-63 213.5 1.5 2.8e-63 213.0 0.0 2.0 2 0 0 2 2 2 1 N-glycosylation protein Mito_carr PF00153.27 GAK64218.1 - 6.6e-70 231.1 0.5 1.1e-23 82.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 GAK64219.1 - 3e-20 72.4 15.0 6.7e-15 54.9 7.9 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK64219.1 - 0.0038 16.1 2.3 0.0038 16.1 2.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MscS_TM PF12794.7 GAK64219.1 - 0.0041 16.0 0.1 0.0041 16.0 0.1 2.9 3 0 0 3 3 3 1 Mechanosensitive ion channel inner membrane domain 1 DUF2569 PF10754.9 GAK64219.1 - 0.35 11.3 5.3 7.3 7.0 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) TRAPPC10 PF12584.8 GAK64220.1 - 1.6e-21 76.7 0.2 2.8e-21 75.8 0.2 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DNA_ligase_A_M PF01068.21 GAK64221.1 - 4.2e-58 196.4 0.0 7e-58 195.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAK64221.1 - 1.9e-45 155.3 0.1 3.1e-45 154.6 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAK64221.1 - 1e-23 83.8 0.0 3e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 GAK64221.1 - 0.001 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 GAK64221.1 - 0.042 13.9 0.2 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain eIF-3c_N PF05470.12 GAK64221.1 - 0.059 11.7 0.1 0.091 11.1 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TrmB PF01978.19 GAK64221.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PBP1_TM PF14812.6 GAK64221.1 - 9.7 6.6 7.1 2.6 8.5 3.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 GAK64222.1 - 4.4e-64 216.4 0.1 9.6e-59 198.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64222.1 - 3.6e-36 124.8 0.1 1.5e-33 116.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 GAK64222.1 - 8.5e-17 60.7 0.4 1.6e-16 59.8 0.4 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 GAK64222.1 - 2.6e-05 23.7 0.1 6.9e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAK64222.1 - 0.00014 21.3 1.6 0.00019 20.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAK64222.1 - 0.00028 19.9 0.2 0.00049 19.1 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain AAA_2 PF07724.14 GAK64223.1 - 2.5e-33 115.6 0.0 1.1e-32 113.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAK64223.1 - 9.4e-13 48.7 0.0 1.9e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAK64223.1 - 5.7e-06 26.7 0.0 2.7e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 GAK64223.1 - 8.7e-06 25.0 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 GAK64223.1 - 6e-05 23.1 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAK64223.1 - 0.0002 21.8 0.1 0.0015 18.9 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain ClpB_D2-small PF10431.9 GAK64223.1 - 0.00039 20.4 0.0 0.96 9.5 0.0 2.5 2 0 0 2 2 2 2 C-terminal, D2-small domain, of ClpB protein AAA_33 PF13671.6 GAK64223.1 - 0.00097 19.3 0.0 0.0049 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAK64223.1 - 0.0042 17.6 0.0 0.0093 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 GAK64223.1 - 0.0082 16.1 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 GAK64223.1 - 0.0096 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.6 GAK64223.1 - 0.026 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAK64223.1 - 0.028 13.8 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GAK64223.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAK64223.1 - 0.04 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 GAK64223.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAK64223.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 GAK64223.1 - 0.086 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAK64223.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 GAK64223.1 - 0.094 12.4 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 GAK64223.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 GAK64223.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAK64223.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 GAK64223.1 - 0.16 12.5 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 GAK64223.1 - 0.2 11.1 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pirin PF02678.16 GAK64224.1 - 2.4e-29 101.5 1.0 6.4e-29 100.1 0.4 1.8 2 0 0 2 2 2 1 Pirin Cupin_2 PF07883.11 GAK64224.1 - 1.5e-09 37.4 0.7 4.6e-08 32.7 0.4 2.6 2 0 0 2 2 2 1 Cupin domain SMC_N PF02463.19 GAK64225.1 - 3.8e-67 226.0 0.0 1.1e-66 224.4 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAK64225.1 - 1.3e-20 73.9 0.4 1.3e-20 73.9 0.4 2.3 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAK64225.1 - 2.3e-10 40.8 8.8 0.00012 22.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 GAK64225.1 - 1.5e-06 27.3 30.9 1.4e-05 24.1 14.4 6.5 3 2 3 6 6 6 3 Spc7 kinetochore protein AAA_23 PF13476.6 GAK64225.1 - 2.7e-06 28.1 37.1 2.7e-06 28.1 37.1 6.2 2 2 0 2 2 1 1 AAA domain Fez1 PF06818.15 GAK64225.1 - 6.5e-06 26.7 14.6 6.5e-06 26.7 14.6 5.5 2 2 3 5 5 5 3 Fez1 AAA_15 PF13175.6 GAK64225.1 - 1.6e-05 24.8 8.1 1.6e-05 24.8 8.1 3.6 2 2 2 4 4 3 1 AAA ATPase domain AAA_29 PF13555.6 GAK64225.1 - 0.00011 21.9 0.1 0.00072 19.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 GAK64225.1 - 0.0021 18.7 7.1 0.0021 18.7 7.1 9.7 6 3 4 10 10 9 4 Clathrin-binding domain of Huntingtin-interacting protein 1 TACC_C PF05010.14 GAK64225.1 - 0.0059 16.4 4.2 0.0059 16.4 4.2 6.9 2 2 4 6 6 3 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ABC_tran PF00005.27 GAK64225.1 - 0.04 14.4 0.0 0.04 14.4 0.0 6.3 5 1 0 5 5 5 0 ABC transporter Filament PF00038.21 GAK64225.1 - 0.13 11.9 73.8 0.18 11.4 18.3 6.9 2 2 3 6 6 6 0 Intermediate filament protein PhoU PF01895.19 GAK64225.1 - 0.41 11.1 19.4 3.8 8.0 1.8 4.8 4 0 0 4 4 4 0 PhoU domain ThiF PF00899.21 GAK64226.1 - 2.4e-14 53.3 0.0 4.9e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 GAK64226.1 - 0.0006 20.0 0.1 0.007 16.5 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Actin PF00022.19 GAK64227.1 - 2.4e-39 135.1 0.0 1.1e-36 126.4 0.0 3.4 2 1 0 2 2 2 2 Actin Cpn10 PF00166.21 GAK64228.1 - 9.3e-27 92.9 0.0 1.1e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 GAK64229.1 - 1.3e-85 287.9 9.6 2.3e-85 287.1 9.6 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Surp PF01805.20 GAK64230.1 - 0.0025 17.8 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Surp module DRY_EERY PF09750.9 GAK64230.1 - 0.021 15.1 0.2 0.083 13.2 0.1 2.1 1 1 0 1 1 1 0 Alternative splicing regulator Tcell_CD4_C PF12104.8 GAK64230.1 - 0.25 11.3 1.4 0.56 10.2 1.4 1.6 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region Mago_nashi PF02792.14 GAK64231.1 - 2.8e-76 254.4 0.2 3.2e-76 254.3 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Tubulin PF00091.25 GAK64232.1 - 1.2e-69 234.5 0.0 1.8e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAK64232.1 - 1.1e-41 142.0 0.2 1.7e-41 141.3 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAK64232.1 - 2.9e-07 30.8 0.0 7.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 GAK64232.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 GAK64232.1 - 0.012 14.9 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin like TPR_2 PF07719.17 GAK64233.1 - 1.5e-08 34.1 26.6 0.0047 16.9 0.2 7.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAK64233.1 - 1.5e-07 31.1 15.5 0.006 16.7 0.2 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK64233.1 - 5.7e-06 26.7 44.4 0.0068 17.1 1.2 9.0 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAK64233.1 - 1.6e-05 25.0 5.4 0.036 14.4 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAK64233.1 - 1.6e-05 24.5 14.5 0.023 14.5 0.2 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64233.1 - 6.9e-05 23.0 9.6 0.0032 17.7 2.2 4.4 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAK64233.1 - 0.0011 19.4 32.3 0.032 14.7 1.4 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAK64233.1 - 0.0027 17.4 5.4 0.7 9.6 0.2 5.1 5 1 0 5 5 5 1 TPR repeat TPR_16 PF13432.6 GAK64233.1 - 0.0033 18.1 2.1 0.0033 18.1 2.1 7.9 6 3 3 9 9 8 3 Tetratricopeptide repeat ChAPs PF09295.10 GAK64233.1 - 0.045 12.8 2.3 0.032 13.2 0.4 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 GAK64233.1 - 0.11 12.6 6.2 3.2 8.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 GAK64234.1 - 3.1e-75 252.9 0.0 4.1e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64234.1 - 9.3e-37 126.7 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 GAK64234.1 - 1.4e-17 64.2 0.0 2e-09 37.9 0.0 3.4 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 GAK64234.1 - 2.6e-08 33.5 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 GAK64234.1 - 2.7e-05 24.2 0.2 5.8e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 GAK64234.1 - 0.0048 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 GAK64234.1 - 0.07 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Na_Ca_ex PF01699.24 GAK64235.1 - 1.5e-36 125.6 36.3 5.9e-20 71.8 12.8 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein ResIII PF04851.15 GAK64238.1 - 2.2e-23 83.1 0.0 4.8e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAK64238.1 - 2.1e-15 57.0 0.0 1.6e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK64238.1 - 3.1e-12 46.6 0.0 5.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 GAK64238.1 - 0.0012 18.0 0.0 0.0027 16.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 GAK64238.1 - 0.0045 16.3 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 GAK64238.1 - 0.0061 16.2 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 GAK64238.1 - 0.018 15.3 0.0 0.07 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAK64238.1 - 0.024 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ERCC3_RAD25_C PF16203.5 GAK64238.1 - 0.025 13.8 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 GAK64238.1 - 0.029 13.1 0.6 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain Spore_SspJ PF09575.10 GAK64238.1 - 0.088 13.2 0.7 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) Phe_tRNA-synt_N PF02912.18 GAK64238.1 - 0.098 12.6 1.3 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain AAA_11 PF13086.6 GAK64238.1 - 0.52 10.1 3.2 8 6.2 0.0 3.0 2 2 0 3 3 3 0 AAA domain CENP-K PF11802.8 GAK64239.1 - 1.6e-11 44.3 16.3 5.8e-07 29.3 0.0 3.2 1 1 2 3 3 3 2 Centromere-associated protein K FeoC PF09012.10 GAK64239.1 - 0.0065 16.5 0.1 0.037 14.1 0.0 2.1 2 0 0 2 2 2 1 FeoC like transcriptional regulator ST7 PF04184.12 GAK64239.1 - 0.19 10.1 1.4 0.29 9.5 1.4 1.2 1 0 0 1 1 1 0 ST7 protein Zn_clus PF00172.18 GAK64240.1 - 8.9e-05 22.5 14.3 0.00013 22.0 14.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Csm1_B PF18211.1 GAK64243.1 - 0.071 13.0 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Csm1 subunit domain B Sacchrp_dh_C PF16653.5 GAK64244.1 - 2.1e-91 306.7 0.0 3.3e-91 306.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 GAK64244.1 - 1.3e-65 220.4 0.0 2.6e-65 219.4 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 GAK64244.1 - 4.9e-25 88.3 0.4 1.6e-24 86.6 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 GAK64244.1 - 4.3e-23 81.0 0.1 7.8e-23 80.1 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAK64244.1 - 0.00063 20.4 0.0 0.0047 17.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 GAK64244.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 GAK64244.1 - 0.013 15.5 0.1 0.057 13.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 GAK64244.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GAK64244.1 - 0.014 15.8 0.0 0.064 13.7 0.0 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 GAK64244.1 - 0.021 15.6 0.1 0.26 12.1 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain TAFII28 PF04719.14 GAK64245.1 - 1.2e-25 89.4 2.3 1.5e-19 69.8 0.1 2.4 2 0 0 2 2 2 2 hTAFII28-like protein conserved region AMP-binding PF00501.28 GAK64246.1 - 4.3e-82 276.0 0.0 5.5e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK64246.1 - 1.8e-12 48.0 0.0 4.6e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GlpM PF06942.12 GAK64246.1 - 0.16 12.4 0.3 0.36 11.3 0.3 1.5 1 0 0 1 1 1 0 GlpM protein SKN1 PF03935.15 GAK64247.1 - 5.3e-183 609.0 0.2 6.1e-183 608.8 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BssS PF13991.6 GAK64248.1 - 0.13 12.3 0.0 0.58 10.3 0.0 1.9 2 0 0 2 2 2 0 BssS protein family Rot1 PF10681.9 GAK64249.1 - 1.3e-46 158.8 0.1 1.6e-46 158.5 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal SKN1 PF03935.15 GAK64250.1 - 3.6e-190 632.6 5.1 4.2e-190 632.4 5.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAK64250.1 - 1e-06 28.4 0.3 0.0044 16.5 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAK64251.1 - 2e-181 603.8 1.5 2.5e-181 603.5 1.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GTP_EFTU PF00009.27 GAK64252.1 - 3.3e-58 196.4 0.1 6.2e-58 195.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAK64252.1 - 6.9e-37 125.9 0.1 2.6e-36 124.1 0.1 2.1 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GAK64252.1 - 4e-31 106.9 0.0 1e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAK64252.1 - 2.9e-22 78.5 0.2 6.9e-22 77.3 0.2 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAK64252.1 - 1.6e-13 50.8 0.0 4e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAK64252.1 - 5.2e-07 29.6 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain adh_short_C2 PF13561.6 GAK64252.1 - 0.029 13.9 0.6 0.079 12.5 0.6 1.7 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase zf-C2H2 PF00096.26 GAK64253.1 - 8.2e-06 26.0 13.4 0.0011 19.3 3.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK64253.1 - 0.00089 19.9 13.8 0.0066 17.2 2.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK64253.1 - 0.0042 17.4 3.3 0.0042 17.4 3.3 3.2 4 0 0 4 4 4 1 Zinc-finger double domain Fer2 PF00111.27 GAK64254.1 - 1e-05 25.4 1.2 1e-05 25.4 1.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DZR PF12773.7 GAK64254.1 - 1.7 8.8 7.0 0.58 10.2 2.8 2.2 2 0 0 2 2 2 0 Double zinc ribbon Fer4_12 PF13353.6 GAK64255.1 - 0.00018 21.8 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAK64255.1 - 0.0093 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 GAK64255.1 - 0.029 14.7 0.0 0.066 13.6 0.0 1.7 1 1 0 1 1 1 0 Radical SAM superfamily Cu-oxidase_3 PF07732.15 GAK64256.1 - 9.8e-39 132.1 4.5 9.1e-38 128.9 1.7 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAK64256.1 - 2.8e-36 124.3 7.8 3.4e-30 104.5 0.2 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 GAK64256.1 - 7e-34 117.2 0.1 1e-32 113.5 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase SpoIIE PF07228.12 GAK64257.1 - 2.3e-06 27.7 0.3 0.21 11.5 0.1 3.4 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAK64257.1 - 9.6e-05 22.1 0.3 0.00043 20.0 0.3 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 GAK64257.1 - 0.00028 20.6 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C Fungal_trans PF04082.18 GAK64259.1 - 7.7e-42 143.2 0.1 1.3e-41 142.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAK64259.1 - 3.1e-08 33.6 10.6 0.00091 19.6 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK64259.1 - 2e-05 25.0 9.5 0.022 15.5 1.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger NOA36 PF06524.12 GAK64259.1 - 0.0076 15.6 11.2 0.012 15.0 11.2 1.2 1 0 0 1 1 1 1 NOA36 protein zf-H2C2_2 PF13465.6 GAK64259.1 - 1.6 9.3 5.0 0.89 10.1 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Peptidase_M48_N PF16491.5 GAK64260.1 - 1.1e-61 207.9 5.5 1.1e-61 207.9 5.5 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GAK64260.1 - 1.3e-32 113.2 1.0 1e-30 107.0 1.0 2.8 1 1 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 GAK64260.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M56 PF05569.11 GAK64260.1 - 0.015 14.5 0.0 0.015 14.5 0.0 2.9 4 0 0 4 4 4 0 BlaR1 peptidase M56 DUF4246 PF14033.6 GAK64262.1 - 2.5e-173 577.4 0.0 3e-173 577.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 GAK64262.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DJ-1_PfpI PF01965.24 GAK64263.1 - 1.2e-21 77.2 0.0 1.6e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Hydrolase_4 PF12146.8 GAK64264.1 - 0.0036 16.6 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF333 PF03891.15 GAK64266.1 - 1.2e-23 83.0 0.0 2e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF333) DUF3712 PF12505.8 GAK64267.1 - 2.4e-88 292.8 33.6 4.3e-17 62.6 0.0 10.2 11 1 1 12 12 12 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAK64267.1 - 6.8e-07 29.8 20.9 0.47 11.0 0.0 9.3 10 1 0 10 10 10 4 Late embryogenesis abundant protein GCR1_C PF12550.8 GAK64268.1 - 6.4e-16 58.4 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 GAK64268.1 - 0.00014 21.0 0.0 0.003 16.7 0.0 2.6 2 2 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Peripla_BP_3 PF13377.6 GAK64268.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Periplasmic binding protein-like domain GGDEF_2 PF17853.1 GAK64268.1 - 0.063 13.5 0.1 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 GGDEF-like domain GMC_oxred_N PF00732.19 GAK64269.1 - 2e-60 204.7 0.0 2.6e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK64269.1 - 1.4e-32 113.2 0.0 2.5e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAK64269.1 - 6.4e-05 22.2 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAK64269.1 - 0.0008 19.1 1.3 0.047 13.3 1.3 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAK64269.1 - 0.0023 18.1 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAK64269.1 - 0.099 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 GAK64269.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Fe_hyd_lg_C PF02906.14 GAK64270.1 - 1.1e-60 205.3 0.0 2e-60 204.5 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain CBP_BcsO PF17037.5 GAK64270.1 - 0.069 13.3 0.5 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO ELFV_dehydrog PF00208.21 GAK64271.1 - 1.6e-80 270.3 2.3 2.2e-80 269.9 2.3 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 GAK64271.1 - 1.5e-46 157.5 0.0 2.9e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 GAK64271.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding B12D PF06522.11 GAK64272.1 - 9.2e-23 79.8 0.1 1.2e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PS_Dcarbxylase PF02666.15 GAK64273.1 - 6.8e-52 175.9 0.0 1.2e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 GAK64273.1 - 3.7e-36 123.5 0.1 2.5e-16 59.9 0.0 3.7 4 0 0 4 4 4 3 C2 domain EF-hand_7 PF13499.6 GAK64273.1 - 7.7e-06 26.3 0.8 1.8e-05 25.1 0.8 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAK64273.1 - 0.00016 21.3 2.2 0.075 13.0 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain Nop14 PF04147.12 GAK64273.1 - 0.1 10.8 4.1 0.15 10.2 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family UBZ_FAAP20 PF15750.5 GAK64273.1 - 0.18 11.8 1.8 0.46 10.5 1.8 1.7 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger BUD22 PF09073.10 GAK64273.1 - 6.2 6.0 9.6 12 5.1 9.6 1.5 1 0 0 1 1 1 0 BUD22 DUF1764 PF08576.10 GAK64274.1 - 1.6e-18 67.4 16.1 8.7e-16 58.7 0.3 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Macoilin PF09726.9 GAK64274.1 - 0.015 13.9 11.2 0.015 13.9 11.2 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 GAK64274.1 - 0.29 9.8 5.8 0.32 9.6 5.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 GAK64274.1 - 2 7.1 9.0 2.3 6.9 9.0 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GAK64274.1 - 2.6 6.8 14.4 2.9 6.6 14.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 GAK64274.1 - 5.2 7.0 18.9 7.5 6.5 18.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CCDC106 PF15794.5 GAK64274.1 - 5.5 6.6 17.6 8.3 6.1 17.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NPR3 PF03666.13 GAK64274.1 - 8.8 5.0 11.6 11 4.7 11.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TPR_1 PF00515.28 GAK64275.1 - 4e-08 32.7 1.6 2e-05 24.2 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAK64275.1 - 8.3e-08 31.8 3.3 7.3e-05 22.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAK64275.1 - 4.6e-05 23.6 2.2 0.00059 20.1 2.2 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAK64275.1 - 5.2e-05 23.8 3.3 5.2e-05 23.8 3.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAK64275.1 - 0.00049 20.6 6.8 0.0081 16.6 2.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK64275.1 - 0.00077 19.6 3.0 0.0013 18.9 3.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAK64275.1 - 0.0057 16.9 3.1 1.2 9.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64275.1 - 0.008 16.4 0.8 0.017 15.3 0.4 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAK64275.1 - 0.0099 15.9 0.1 0.03 14.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAK64275.1 - 0.03 14.2 2.5 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAK64275.1 - 0.052 14.2 0.4 0.51 11.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK64275.1 - 0.085 13.5 7.1 0.22 12.3 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAK64275.1 - 0.15 12.3 0.9 7.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK64275.1 - 0.16 12.9 4.4 0.18 12.7 1.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 GAK64276.1 - 5.7e-71 238.3 78.5 2.9e-39 134.7 30.9 2.8 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAK64276.1 - 6.6e-36 123.8 0.0 2e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAK64276.1 - 2.3e-30 104.4 0.4 1.5e-23 82.5 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAK64276.1 - 1.3e-09 38.5 0.1 3.1e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 GAK64276.1 - 8.8e-07 29.5 0.0 0.058 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAK64276.1 - 9.5e-06 25.3 0.9 0.01 15.5 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAK64276.1 - 0.0001 22.2 0.1 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 GAK64276.1 - 0.00023 21.3 0.1 0.93 9.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAK64276.1 - 0.00029 21.1 0.3 0.69 10.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 GAK64276.1 - 0.00038 20.0 0.0 0.0062 16.0 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAK64276.1 - 0.00051 19.9 0.0 0.72 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAK64276.1 - 0.0017 18.9 0.0 1.5 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 GAK64276.1 - 0.0037 16.4 16.3 0.0037 16.4 16.3 3.1 2 1 1 3 3 3 1 ABC-2 family transporter protein NACHT PF05729.12 GAK64276.1 - 0.0077 16.2 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 GAK64276.1 - 0.011 15.3 0.7 0.23 11.0 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 GAK64276.1 - 0.02 15.0 0.5 6.2 6.9 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 GAK64276.1 - 0.026 14.1 0.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAK64276.1 - 0.036 13.8 0.2 6 6.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAK64276.1 - 0.055 13.2 0.9 5.7 6.6 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAK64276.1 - 0.093 13.0 0.2 0.82 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAK64276.1 - 0.17 12.3 0.0 24 5.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAK64276.1 - 0.69 9.2 3.0 6.7 5.9 0.2 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 GAK64276.1 - 1.2 9.5 2.7 22 5.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain RSN1_7TM PF02714.15 GAK64277.1 - 1.2e-32 113.3 25.7 1.8e-32 112.7 25.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAK64277.1 - 6.6e-16 59.0 0.1 2.4e-11 44.2 0.1 2.9 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAK64277.1 - 1.1e-15 57.7 1.8 1.1e-15 57.7 1.8 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PALP PF00291.25 GAK64279.1 - 3.5e-56 190.8 0.1 1.3e-38 133.1 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme AA_permease_2 PF13520.6 GAK64280.1 - 5e-55 187.1 46.0 6.2e-55 186.7 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAK64280.1 - 5.6e-17 61.5 46.8 1.3e-16 60.2 46.9 1.5 1 1 0 1 1 1 1 Amino acid permease ADH_N PF08240.12 GAK64281.1 - 2e-29 101.6 0.6 3.6e-29 100.8 0.2 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK64281.1 - 2.7e-26 92.1 0.5 4e-26 91.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK64281.1 - 0.00015 22.9 0.2 0.00024 22.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CPSF_A PF03178.15 GAK64282.1 - 1.6e-41 142.7 0.0 3.5e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 GAK64282.1 - 5.5e-39 134.1 0.0 1.3e-38 132.9 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Aminotran_4 PF01063.19 GAK64284.1 - 1.8e-17 63.9 0.0 2.4e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV BOF PF04076.13 GAK64284.1 - 0.18 11.9 0.0 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial OB fold (BOF) protein vATP-synt_AC39 PF01992.16 GAK64285.1 - 1.4e-113 379.9 0.4 1.5e-113 379.7 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Zn_clus PF00172.18 GAK64286.1 - 3e-05 24.1 9.2 7e-05 22.9 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK64286.1 - 0.003 16.6 0.0 0.0071 15.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2054 PF10218.9 GAK64286.1 - 0.029 14.5 4.1 0.062 13.4 4.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) SEN1_N PF12726.7 GAK64287.1 - 5.9e-160 534.0 6.1 8.3e-160 533.5 6.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 GAK64287.1 - 1.9e-67 227.8 0.3 6.3e-67 226.1 0.3 1.9 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 GAK64287.1 - 7.2e-61 205.3 0.0 1.4e-60 204.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK64287.1 - 9.1e-11 42.3 0.0 7.7e-10 39.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAK64287.1 - 1.9e-07 31.0 3.0 8.6e-05 22.3 0.3 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 GAK64287.1 - 9.3e-05 22.3 0.6 0.43 10.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 GAK64287.1 - 0.00099 18.9 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain IMUP PF15761.5 GAK64287.1 - 0.0015 19.2 2.9 0.0015 19.2 2.9 3.2 2 0 0 2 2 2 1 Immortalisation up-regulated protein UvrD-helicase PF00580.21 GAK64287.1 - 0.0066 16.0 0.2 0.48 9.9 0.1 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 GAK64287.1 - 0.016 15.5 1.1 5.9 7.2 0.2 3.6 3 0 0 3 3 3 0 AAA domain Helicase_RecD PF05127.14 GAK64287.1 - 0.018 14.9 0.5 1.2 8.9 0.0 3.0 2 0 0 2 2 2 0 Helicase LegC3_N PF18654.1 GAK64287.1 - 0.054 12.7 1.3 0.11 11.7 1.3 1.4 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain UvrD_C PF13361.6 GAK64287.1 - 0.078 12.3 0.1 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Sugar_tr PF00083.24 GAK64292.1 - 5.8e-30 104.6 28.3 5.9e-19 68.3 13.7 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAK64292.1 - 1.5e-16 60.3 35.8 6e-10 38.6 18.3 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAK64292.1 - 4.7e-05 22.1 17.6 0.0028 16.3 0.1 4.0 4 0 0 4 4 4 3 MFS/sugar transport protein BT1 PF03092.16 GAK64292.1 - 0.028 12.7 9.4 0.27 9.4 0.8 3.1 4 0 0 4 4 4 0 BT1 family LHC PF00556.20 GAK64292.1 - 4.5 7.6 6.8 1.8 8.8 0.4 3.5 3 0 0 3 3 3 0 Antenna complex alpha/beta subunit Aldo_ket_red PF00248.21 GAK64294.1 - 6.5e-53 179.8 0.0 4.9e-52 177.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Transket_pyr PF02779.24 GAK64294.1 - 4.1e-41 140.6 0.5 4.2e-40 137.3 0.1 2.3 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAK64294.1 - 2.1e-28 98.7 0.0 6.3e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_L10 PF00466.20 GAK64294.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 WD40 PF00400.32 GAK64295.1 - 1.7e-25 88.8 15.2 5e-05 24.0 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64295.1 - 1.2e-18 67.2 0.5 0.00011 22.4 0.0 5.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAK64295.1 - 0.0013 18.7 0.0 0.061 13.2 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAK64295.1 - 0.034 12.8 2.4 0.66 8.5 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 GAK64295.1 - 0.11 12.5 0.1 1.3e+02 2.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GAK64295.1 - 0.11 11.0 1.2 0.73 8.3 0.6 1.9 1 1 0 2 2 2 0 Cytochrome D1 heme domain NDK PF00334.19 GAK64296.1 - 2.7e-56 189.3 0.0 3.3e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDT80_PhoG PF05224.12 GAK64297.1 - 2.1e-16 60.7 0.0 3.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AOX PF01786.17 GAK64298.1 - 9.7e-101 335.8 0.4 1.2e-100 335.5 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 GAK64298.1 - 0.0045 16.8 0.1 0.23 11.2 0.0 2.5 2 1 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 Ribosomal_L34e PF01199.18 GAK64299.1 - 7.8e-40 135.1 5.1 1.7e-39 134.1 5.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L34e DR2241 PF18069.1 GAK64299.1 - 0.098 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 DR2241 stabilising domain Ribosomal_L6 PF00347.23 GAK64300.1 - 5.2e-20 71.9 0.7 6.5e-12 46.0 0.0 3.8 3 1 0 3 3 3 2 Ribosomal protein L6 R3H-assoc PF13902.6 GAK64301.1 - 0.011 16.1 0.5 0.011 16.1 0.5 2.5 2 0 0 2 2 2 0 R3H-associated N-terminal domain DUF953 PF06110.11 GAK64304.1 - 1.7e-15 56.7 0.0 1.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 GAK64304.1 - 0.00016 21.6 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAK64304.1 - 0.089 12.6 0.9 0.12 12.1 0.9 1.4 1 1 0 1 1 1 0 Thioredoxin UDG PF03167.19 GAK64305.1 - 2.7e-17 63.2 0.0 3.8e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Hamartin PF04388.12 GAK64305.1 - 5.7 5.5 14.4 9.2 4.8 14.4 1.3 1 0 0 1 1 1 0 Hamartin protein Aldedh PF00171.22 GAK64306.1 - 4.1e-182 605.8 0.3 4.6e-182 605.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAK64306.1 - 0.0065 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 GAK64306.1 - 0.047 13.1 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Fungal_trans_2 PF11951.8 GAK64307.1 - 2.3e-15 56.3 0.0 5.5e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK64307.1 - 0.00035 20.6 12.0 0.00083 19.4 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OKR_DC_1_N PF03709.15 GAK64307.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain OPT PF03169.15 GAK64308.1 - 7.6e-101 338.6 40.6 9.4e-101 338.3 40.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DNase_NucA_NucB PF14040.6 GAK64309.1 - 3.6e-27 95.0 3.3 5.4e-27 94.5 3.3 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB ADH_N PF08240.12 GAK64310.1 - 1.2e-23 83.1 0.3 2.1e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK64310.1 - 1.6e-12 47.6 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAK64310.1 - 0.03 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAK64310.1 - 0.043 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 GAK64310.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 GAK64310.1 - 0.087 12.7 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DNA_pol_E_B PF04042.16 GAK64311.1 - 4.3e-44 150.4 0.2 6.9e-44 149.7 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Glyco_hydro_18 PF00704.28 GAK64312.1 - 2e-16 60.6 0.9 3.2e-16 59.9 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Zn_clus PF00172.18 GAK64313.1 - 6.2e-05 23.0 10.1 0.00013 22.0 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LIME1 PF15332.6 GAK64314.1 - 0.13 11.8 0.6 0.24 11.0 0.6 1.3 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 HbrB PF08539.11 GAK64315.1 - 1.3e-50 171.7 0.0 2.5e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 HbrB-like His_Phos_1 PF00300.22 GAK64315.1 - 1.1e-33 116.5 0.0 2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ras PF00071.22 GAK64316.1 - 6.3e-20 71.4 0.0 8e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK64316.1 - 1.6e-10 41.3 0.0 2.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 GAK64316.1 - 3.2e-05 23.4 0.1 5.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 GAK64316.1 - 0.00013 22.1 0.1 0.00023 21.3 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 GAK64316.1 - 0.00058 19.6 0.3 0.0011 18.7 0.3 1.4 1 1 0 1 1 1 1 Sigma-54 interaction domain Gtr1_RagA PF04670.12 GAK64316.1 - 0.0092 15.4 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region NACHT PF05729.12 GAK64316.1 - 0.0096 15.9 0.1 0.049 13.5 0.1 1.9 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 GAK64316.1 - 0.013 15.5 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAK64316.1 - 0.014 15.1 0.1 0.039 13.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 GAK64316.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 GAK64316.1 - 0.016 15.5 0.1 0.052 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 GAK64316.1 - 0.017 14.3 0.2 0.031 13.4 0.2 1.4 1 0 0 1 1 1 0 G-protein alpha subunit KAP_NTPase PF07693.14 GAK64316.1 - 0.024 13.9 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 GAK64316.1 - 0.026 13.8 0.2 0.051 12.9 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 GAK64316.1 - 0.071 12.6 0.3 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 GAK64316.1 - 0.081 13.0 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 GAK64316.1 - 0.1 12.6 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 GAK64316.1 - 0.11 12.3 0.2 0.57 9.9 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 GAK64316.1 - 0.13 12.0 0.1 0.49 10.1 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 GAK64316.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NB-ARC PF00931.22 GAK64316.1 - 0.15 11.2 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 GAK64316.1 - 0.16 12.5 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Caleosin PF05042.13 GAK64317.1 - 1.5e-65 220.3 0.0 1.9e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Pkinase PF00069.25 GAK64319.1 - 8.3e-19 68.0 0.0 6.5e-17 61.8 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64319.1 - 5.3e-07 29.2 0.0 1.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAK64319.1 - 0.0014 18.6 0.9 0.003 17.5 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAK64319.1 - 0.0091 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 GAK64319.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAK64319.1 - 0.13 11.8 0.0 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family MIT PF04212.18 GAK64320.1 - 0.027 14.5 1.6 0.098 12.7 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PPP4R2 PF09184.11 GAK64320.1 - 0.16 11.6 2.2 0.32 10.5 2.2 1.4 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 GAK64320.1 - 1.9 7.0 9.3 4.4 5.8 9.3 1.6 1 0 0 1 1 1 0 Hamartin protein Inositol_P PF00459.25 GAK64321.1 - 2.9e-64 217.2 0.1 3.4e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family HLH PF00010.26 GAK64322.1 - 1.3e-09 37.9 0.5 4.8e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Topoisom_bac PF01131.20 GAK64324.1 - 1.5e-100 337.1 0.0 1.8e-100 336.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 GAK64324.1 - 3e-23 81.6 10.1 4.7e-14 52.2 1.0 2.8 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 GAK64324.1 - 1.2e-19 70.4 0.1 6.4e-19 68.1 0.0 2.2 2 1 0 2 2 2 1 Toprim domain zf-CCHC PF00098.23 GAK64324.1 - 3.3e-13 49.0 14.0 3.8e-07 29.9 3.0 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 GAK64324.1 - 2.1e-07 30.8 8.4 0.00075 19.4 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 GAK64324.1 - 1.5e-06 27.8 11.4 0.001 18.8 0.8 2.6 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GAK64324.1 - 9.8e-06 25.3 12.7 0.0028 17.4 3.4 2.5 2 0 0 2 2 2 2 Zinc knuckle OPT PF03169.15 GAK64325.1 - 1.8e-140 469.5 15.7 2.1e-140 469.3 15.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ARL6IP6 PF15062.6 GAK64325.1 - 0.011 15.8 0.0 0.079 13.1 0.1 2.3 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Phage_holin_2_1 PF04971.12 GAK64325.1 - 0.095 12.7 7.3 1.4 8.9 0.0 3.6 4 0 0 4 4 4 0 Bacteriophage P21 holin S Cation_ATPase_C PF00689.21 GAK64325.1 - 2.4 7.8 7.2 2.3 7.9 1.0 2.9 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus PALP PF00291.25 GAK64326.1 - 3.9e-34 118.4 0.0 8.2e-33 114.1 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 GAK64326.1 - 0.00051 20.5 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain Pkinase PF00069.25 GAK64327.1 - 1.1e-56 192.2 0.1 2e-35 122.5 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64327.1 - 3.3e-24 85.6 0.3 2.2e-16 59.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAK64327.1 - 0.008 15.2 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAK64327.1 - 0.0097 15.2 0.0 0.034 13.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 GAK64327.1 - 0.079 13.7 0.0 0.31 11.8 0.0 2.2 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF1028 PF06267.12 GAK64327.1 - 0.1 12.4 0.5 0.19 11.5 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF1028) RIO1 PF01163.22 GAK64327.1 - 0.13 11.8 0.6 0.98 9.0 0.0 2.3 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 GAK64327.1 - 5.1 6.9 11.1 0.16 11.9 0.2 3.3 4 1 0 4 4 4 0 Phosphotransferase enzyme family Glyco_hydro_31 PF01055.26 GAK64328.1 - 1.5e-126 423.2 3.0 2.3e-126 422.6 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAK64328.1 - 6.8e-25 87.5 0.0 1.5e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAK64328.1 - 0.012 15.9 0.1 0.032 14.5 0.1 1.8 1 0 0 1 1 1 0 Galactose mutarotase-like HAMP PF00672.25 GAK64329.1 - 1.3e-37 128.0 18.6 4.3e-08 33.4 0.4 9.1 8 2 1 9 9 9 6 HAMP domain HATPase_c PF02518.26 GAK64329.1 - 1e-27 96.8 0.1 3.4e-27 95.2 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAK64329.1 - 9.5e-25 86.9 0.9 6.5e-24 84.3 0.8 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAK64329.1 - 5.5e-16 58.4 1.9 2.1e-15 56.5 0.3 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF3829 PF12889.7 GAK64329.1 - 0.055 13.0 0.7 13 5.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3829) SpoIIID PF12116.8 GAK64329.1 - 0.26 11.4 1.3 25 5.1 0.0 4.3 6 0 0 6 6 6 0 Stage III sporulation protein D Rab5-bind PF09311.11 GAK64329.1 - 0.6 9.4 8.9 5.8 6.2 0.1 4.3 3 2 2 5 5 5 0 Rabaptin-like protein ApoLp-III PF07464.11 GAK64329.1 - 7.8 6.6 18.0 8 6.5 0.1 6.0 3 2 3 7 7 7 0 Apolipophorin-III precursor (apoLp-III) Yippee-Mis18 PF03226.14 GAK64331.1 - 1.3e-11 44.7 0.1 2.4e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SKG6 PF08693.10 GAK64331.1 - 2.5e-06 26.8 0.1 5.6e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 GAK64331.1 - 0.015 15.1 3.5 0.029 14.2 0.3 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 NLE PF08154.12 GAK64332.1 - 1.3e-16 60.9 0.0 2.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 GAK64332.1 - 2e-13 50.6 8.4 0.075 13.9 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Metallophos PF00149.28 GAK64332.1 - 4.2e-09 37.2 0.4 9.3e-09 36.1 0.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAK64332.1 - 1.1e-05 25.8 0.5 0.00025 21.3 0.2 2.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ANAPC4_WD40 PF12894.7 GAK64332.1 - 0.0087 16.3 0.1 0.53 10.6 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 GAK64333.1 - 5.1e-19 68.6 0.0 1.3e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 GAK64333.1 - 3.1e-08 33.5 0.4 5.2e-08 32.8 0.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAK64333.1 - 1.5e-05 24.9 0.7 2.5e-05 24.1 0.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAK64333.1 - 6e-05 23.1 0.4 0.00012 22.2 0.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAK64333.1 - 0.0016 18.7 0.7 0.0027 18.0 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAK64333.1 - 0.0022 17.8 0.8 0.0039 17.0 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK64333.1 - 0.0045 16.8 1.2 0.0078 16.1 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK64333.1 - 0.0053 16.6 0.6 0.011 15.6 0.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAK64333.1 - 0.03 14.1 1.5 0.052 13.4 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) T3SSipB PF16535.5 GAK64333.1 - 0.13 12.7 1.9 0.31 11.5 1.9 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB zf-C2HC5 PF06221.13 GAK64333.1 - 0.17 11.9 0.3 0.37 10.8 0.3 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Sec16_C PF12931.7 GAK64334.1 - 5e-105 351.5 0.0 7e-105 351.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 GAK64334.1 - 1.2e-27 96.8 0.0 3.1e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region XPA_C PF05181.12 GAK64335.1 - 5.3e-23 80.7 1.9 9.1e-23 80.0 1.9 1.4 1 0 0 1 1 1 1 XPA protein C-terminus DUF1451 PF07295.11 GAK64335.1 - 0.018 15.1 0.4 0.018 15.1 0.4 2.9 3 1 0 3 3 3 0 Zinc-ribbon containing domain DZR PF12773.7 GAK64335.1 - 0.027 14.5 0.6 5.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon XPA_N PF01286.18 GAK64335.1 - 2.3 8.3 5.6 0.69 10.0 1.5 2.3 2 1 0 2 2 2 0 XPA protein N-terminal Nudix_N_2 PF14803.6 GAK64335.1 - 2.8 7.9 5.9 28 4.8 0.1 3.4 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 GAK64335.1 - 9.9 6.0 7.2 23 4.9 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Glyco_hydro_63 PF03200.16 GAK64336.1 - 4.2e-163 543.6 0.0 3.5e-162 540.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 GAK64336.1 - 9.5e-70 235.2 0.0 1.6e-69 234.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 GAK64336.1 - 8.2e-07 28.2 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 GAK64336.1 - 0.006 15.9 0.1 0.013 14.8 0.1 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SMI1_KNR4 PF09346.10 GAK64337.1 - 8.8e-26 90.9 0.0 1.5e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) zf-met2 PF12907.7 GAK64338.1 - 3.2e-14 52.8 0.8 5.1e-14 52.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 GAK64338.1 - 0.0012 19.7 11.4 0.0012 19.7 11.4 1.9 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_12 PF18658.1 GAK64338.1 - 0.023 14.3 0.1 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type Gpi16 PF04113.14 GAK64340.1 - 1.1e-101 341.0 0.2 3.2e-99 332.9 0.2 3.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Ferric_reduct PF01794.19 GAK64341.1 - 1.5e-16 60.6 10.5 1.5e-16 60.6 10.5 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAK64341.1 - 3e-16 59.5 0.0 9.3e-14 51.4 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAK64341.1 - 9.8e-14 51.8 0.0 5.3e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF4171 PF13775.6 GAK64341.1 - 0.086 13.3 2.8 0.25 11.8 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Peptidase_A22B PF04258.13 GAK64342.1 - 2.1e-79 267.0 5.0 2.8e-79 266.6 5.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 GAK64342.1 - 9.5e-08 31.8 5.1 1.7e-07 31.0 5.1 1.3 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease CENP-B_dimeris PF09026.10 GAK64342.1 - 0.0032 17.8 0.8 0.0032 17.8 0.8 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.6 GAK64342.1 - 0.033 13.9 3.6 1.5 8.5 0.8 2.6 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 GAK64342.1 - 0.051 13.9 8.1 0.057 13.8 0.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 GAK64342.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Astro_capsid_p PF12226.8 GAK64342.1 - 3.1 6.8 6.2 5.7 6.0 6.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DnaJ_C PF01556.18 GAK64343.1 - 1.3e-41 142.2 0.5 1.7e-41 141.7 0.5 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAK64343.1 - 4.7e-20 71.5 1.1 8e-20 70.7 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAK64343.1 - 4.4e-17 62.2 20.1 7.4e-17 61.5 20.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAK64343.1 - 0.004 17.1 10.0 0.031 14.2 1.1 2.7 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 GAK64343.1 - 0.33 10.6 7.0 0.56 9.9 1.9 2.2 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 GAK64343.1 - 0.83 9.7 11.3 4 7.5 3.4 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 GAK64343.1 - 7.1 6.7 9.9 85 3.2 9.6 2.2 1 1 0 1 1 1 0 zinc-ribbons Glyco_hydro_25 PF01183.20 GAK64344.1 - 1.7e-45 155.4 0.1 1.9e-45 155.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 SIS PF01380.22 GAK64346.1 - 1.4e-16 60.5 0.0 4.1e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 GAK64346.1 - 9.5e-08 32.2 0.0 0.0059 16.6 0.0 2.6 1 1 1 2 2 2 2 SIS domain MFS_1 PF07690.16 GAK64347.1 - 2.6e-41 141.7 35.4 2.6e-41 141.7 35.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAK64347.1 - 1e-07 31.6 6.6 1e-07 31.6 6.6 2.7 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB UNC-93 PF05978.16 GAK64347.1 - 0.63 9.7 8.1 0.049 13.3 2.2 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 YTH PF04146.15 GAK64348.1 - 3.2e-40 137.8 0.0 6.2e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain PapG_N PF03627.13 GAK64348.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain ThiF PF00899.21 GAK64350.1 - 6e-57 192.8 0.0 1e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family RabGAP-TBC PF00566.18 GAK64350.1 - 1.9e-31 109.4 0.1 8.7e-16 58.2 0.1 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 GAK64350.1 - 4.3e-05 24.0 0.0 0.00023 21.6 0.0 2.3 2 1 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 GAK64350.1 - 0.00067 19.7 0.1 0.0015 18.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAK64350.1 - 0.07 13.4 0.9 0.34 11.2 0.9 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 GAK64350.1 - 0.078 13.4 0.1 0.21 12.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 GAK64350.1 - 0.085 12.1 1.3 0.1 11.9 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TFIIIC_delta PF12657.7 GAK64351.1 - 8.6e-11 42.1 0.1 2.8e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 GAK64351.1 - 2.1e-08 34.0 0.1 5.5e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex GATase PF00117.28 GAK64351.1 - 0.00017 21.4 0.0 0.00052 19.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DnaJ-X PF14308.6 GAK64352.1 - 4.4e-67 225.6 1.0 4.4e-67 225.6 1.0 2.7 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAK64352.1 - 3.6e-18 65.5 0.2 3.6e-18 65.5 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain PAT1 PF09770.9 GAK64352.1 - 0.0012 17.3 5.7 0.0016 16.9 5.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Microtub_bd PF16796.5 GAK64352.1 - 0.068 13.1 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Microtubule binding PIN_12 PF16289.5 GAK64352.1 - 0.67 10.4 7.8 2 8.9 7.8 1.9 1 0 0 1 1 1 0 PIN domain DUF5499 PF17603.2 GAK64352.1 - 0.89 10.2 3.8 1.9 9.1 0.4 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5499) PIF1 PF05970.14 GAK64353.1 - 1.2e-61 208.9 0.7 7e-49 166.9 0.1 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GAK64353.1 - 1.5e-26 93.3 0.0 2.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK64353.1 - 9.8e-13 48.7 0.0 8.9e-12 45.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 GAK64353.1 - 8.5e-07 29.3 0.4 1.3e-05 25.5 0.0 3.0 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 GAK64353.1 - 8.5e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 GAK64353.1 - 9.7e-05 22.8 0.4 0.00048 20.6 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 GAK64353.1 - 0.00018 21.4 0.2 0.022 14.5 0.1 3.1 3 1 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 GAK64353.1 - 0.00036 21.0 0.2 0.001 19.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 GAK64353.1 - 0.003 17.4 1.0 0.017 14.9 0.1 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 GAK64353.1 - 0.0039 17.7 0.0 0.014 15.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 GAK64353.1 - 0.0065 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 GAK64353.1 - 0.0065 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 GAK64353.1 - 0.007 15.7 0.1 0.019 14.2 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 GAK64353.1 - 0.0083 15.9 0.5 0.094 12.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 GAK64353.1 - 0.011 15.7 0.1 0.62 10.0 0.0 2.7 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 GAK64353.1 - 0.015 14.2 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 GAK64353.1 - 0.017 15.1 0.0 0.1 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.6 GAK64353.1 - 0.021 13.7 0.0 0.047 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAK64353.1 - 0.023 14.4 0.1 0.098 12.3 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 GAK64353.1 - 0.026 14.5 0.0 0.07 13.1 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 GAK64353.1 - 0.031 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 GAK64353.1 - 0.032 14.6 0.0 0.1 13.0 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 GAK64353.1 - 0.033 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAK64353.1 - 0.033 14.2 0.2 0.48 10.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 GAK64353.1 - 0.045 13.7 0.1 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 GAK64353.1 - 0.062 12.7 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.23 GAK64353.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Herpes_Helicase PF02689.14 GAK64353.1 - 0.07 11.0 0.0 0.34 8.8 0.0 1.9 2 0 0 2 2 2 0 Helicase Helicase_RecD PF05127.14 GAK64353.1 - 0.11 12.4 0.4 0.43 10.4 0.4 1.9 1 1 0 1 1 1 0 Helicase SH3_13 PF18335.1 GAK64353.1 - 0.11 12.3 0.1 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain UvrD-helicase PF00580.21 GAK64353.1 - 0.21 11.0 1.0 0.23 11.0 0.1 1.6 2 0 0 2 2 1 0 UvrD/REP helicase N-terminal domain Exotox-A_target PF09102.10 GAK64353.1 - 0.47 10.4 3.9 2.9 7.9 0.0 3.2 3 0 0 3 3 3 0 Exotoxin A, targeting Cys_Met_Meta_PP PF01053.20 GAK64354.1 - 6.8e-55 186.1 0.1 2.1e-46 158.2 0.1 2.6 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAK64354.1 - 0.0038 16.5 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAK64354.1 - 0.036 13.0 0.2 0.059 12.3 0.2 1.4 1 0 0 1 1 1 0 Aminotransferase class-V zf-C2H2 PF00096.26 GAK64355.1 - 0.061 13.8 0.2 0.2 12.2 0.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2420 PF10336.9 GAK64357.1 - 3.8e-16 59.1 0.0 7.5e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) VlpA_repeat PF04649.12 GAK64357.1 - 0.95 9.8 4.1 17 5.9 0.6 3.4 2 0 0 2 2 2 0 Mycoplasma hyorhinis VlpA repeat Thiolase_N PF00108.23 GAK64358.1 - 1.3e-76 257.4 5.2 2.1e-76 256.8 5.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAK64358.1 - 2.5e-42 143.4 0.7 2.5e-42 143.4 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 GAK64358.1 - 0.0033 17.5 0.1 0.013 15.7 0.1 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 GAK64358.1 - 0.0065 16.1 0.4 0.0065 16.1 0.4 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Histone PF00125.24 GAK64359.1 - 4.3e-50 169.5 3.3 6.5e-50 168.9 3.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAK64359.1 - 0.00013 22.3 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAK64359.1 - 0.00025 21.1 0.1 0.00057 20.0 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 GAK64359.1 - 0.00089 19.9 2.2 0.0015 19.1 2.2 1.3 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 GAK64359.1 - 0.0029 17.9 0.1 0.0067 16.7 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 GAK64360.1 - 7.6e-08 32.5 0.1 9.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 GAK64360.1 - 0.00021 21.4 0.1 0.00032 20.8 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 GAK64360.1 - 0.00047 20.5 0.0 0.00062 20.1 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 GAK64360.1 - 0.00062 20.1 0.1 0.0007 20.0 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAK64360.1 - 0.00091 19.5 0.1 0.0019 18.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAK64360.1 - 0.05 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Reprolysin_5 PF13688.6 GAK64361.1 - 1.3e-42 146.2 9.1 1.3e-42 146.2 9.1 3.2 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 GAK64361.1 - 6.2e-40 137.2 5.4 1.6e-39 135.8 5.4 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Cyclin PF08613.11 GAK64361.1 - 3.4e-38 131.6 0.1 9.2e-23 81.4 0.0 3.5 2 0 0 2 2 2 2 Cyclin Reprolysin_4 PF13583.6 GAK64361.1 - 2.3e-37 128.6 3.6 8.5e-37 126.8 3.6 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 GAK64361.1 - 2.4e-15 57.1 25.7 2.4e-15 57.1 25.7 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 GAK64361.1 - 2.9e-11 44.0 0.1 7.7e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 GAK64361.1 - 5.8e-07 29.8 0.6 1.2e-06 28.8 0.6 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 GAK64361.1 - 1.4e-06 28.4 7.6 4.9e-05 23.3 7.6 2.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 GAK64361.1 - 0.00015 22.2 10.1 0.00015 22.2 10.1 3.7 1 1 2 3 3 3 1 ADAM cysteine-rich domain HMG_box PF00505.19 GAK64363.1 - 2.5e-11 43.8 2.3 4.3e-11 43.1 2.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box PAP1 PF08601.10 GAK64363.1 - 0.00027 20.8 11.0 0.00027 20.8 11.0 2.5 2 0 0 2 2 2 1 Transcription factor PAP1 HMG_box_2 PF09011.10 GAK64363.1 - 0.0014 19.2 0.2 0.0029 18.2 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DHC PF09626.10 GAK64363.1 - 0.012 16.5 0.2 1.2 10.0 0.0 2.5 2 0 0 2 2 2 0 Dihaem cytochrome c MATalpha_HMGbox PF04769.12 GAK64363.1 - 0.23 10.7 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box VbhA PF18495.1 GAK64363.1 - 4.4 7.2 7.0 23 4.9 0.2 3.3 4 0 0 4 4 4 0 Antitoxin VbhA Ribosomal_S4e PF00900.20 GAK64364.1 - 5.7e-36 122.3 0.1 1.2e-35 121.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 GAK64364.1 - 1.4e-22 79.0 0.1 2.9e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 GAK64364.1 - 1.6e-07 31.3 0.1 3.5e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 GAK64364.1 - 9e-05 22.3 1.6 0.00035 20.4 1.6 2.1 1 0 0 1 1 1 1 KOW motif S4 PF01479.25 GAK64364.1 - 0.00028 20.5 0.0 0.00064 19.4 0.0 1.7 1 0 0 1 1 1 1 S4 domain MFS_1 PF07690.16 GAK64368.1 - 8.5e-10 38.1 23.9 8.5e-10 38.1 23.9 4.0 4 1 0 4 4 4 2 Major Facilitator Superfamily DUF2939 PF11159.8 GAK64368.1 - 0.072 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Sin3a_C PF16879.5 GAK64369.1 - 1.4e-78 264.5 0.0 9e-78 261.9 0.0 2.4 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 GAK64369.1 - 4.9e-42 141.8 7.1 3.9e-18 65.3 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAK64369.1 - 1.8e-41 140.1 0.1 5e-41 138.7 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Ribosomal_S21e PF01249.18 GAK64370.1 - 1.3e-35 121.3 0.0 2.1e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21e MFS_1 PF07690.16 GAK64371.1 - 2.2e-29 102.5 30.3 3.1e-29 102.0 30.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK64371.1 - 3.3e-05 22.9 22.8 0.0001 21.3 22.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter HlyIII PF03006.20 GAK64371.1 - 7.9 6.1 12.9 0.26 11.0 5.3 2.2 1 1 0 2 2 2 0 Haemolysin-III related MARVEL PF01284.23 GAK64372.1 - 0.00026 21.1 19.5 0.036 14.1 7.1 3.1 1 1 2 3 3 3 3 Membrane-associating domain Yip1 PF04893.17 GAK64372.1 - 0.21 11.3 21.2 0.67 9.7 12.1 2.2 2 0 0 2 2 2 0 Yip1 domain DUF4064 PF13273.6 GAK64372.1 - 3.3 8.0 16.1 1.1 9.6 0.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Cytochrom_C PF00034.21 GAK64373.1 - 5.8e-11 43.4 0.0 7.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GAK64373.1 - 6e-09 36.1 1.2 3.3e-08 33.7 1.2 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAK64373.1 - 6.1e-05 22.7 1.8 0.00074 19.2 1.8 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain VanZ PF04892.12 GAK64374.1 - 4.2e-05 24.2 0.7 8.3e-05 23.3 0.7 1.5 1 1 0 1 1 1 1 VanZ like family DUF4203 PF13886.6 GAK64374.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Rot1 PF10681.9 GAK64375.1 - 1e-53 182.0 1.5 1.3e-53 181.7 1.5 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF2040 PF09745.9 GAK64376.1 - 2.9e-36 124.2 19.5 2.9e-36 124.2 19.5 3.0 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Vps55 PF04133.14 GAK64377.1 - 2.6e-43 146.7 6.3 3e-43 146.5 6.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 zf-RING_4 PF14570.6 GAK64379.1 - 1e-21 76.4 11.6 1.7e-21 75.7 11.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GAK64379.1 - 9.7e-07 28.6 8.9 1.6e-06 27.9 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK64379.1 - 4e-05 23.4 8.9 0.00057 19.7 5.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 GAK64379.1 - 0.0025 17.6 0.1 0.0097 15.7 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 GAK64379.1 - 0.0041 17.4 11.8 0.0069 16.7 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 GAK64379.1 - 0.031 14.4 4.2 0.062 13.4 4.2 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 GAK64379.1 - 0.3 11.0 11.5 0.55 10.1 11.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LpxK PF02606.14 GAK64379.1 - 0.67 9.0 5.8 0.062 12.4 0.6 1.8 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase zf-C3HC4 PF00097.25 GAK64379.1 - 0.77 9.7 11.5 1.4 8.9 11.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK64379.1 - 1.5 8.9 7.9 7.8 6.6 8.5 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Baculo_IE-1 PF05290.11 GAK64379.1 - 1.6 8.7 9.6 0.5 10.3 6.2 1.8 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) TFIIA PF03153.13 GAK64379.1 - 7.8 6.4 0.0 7.8 6.4 0.0 4.3 2 2 1 4 4 2 0 Transcription factor IIA, alpha/beta subunit SRP54 PF00448.22 GAK64380.1 - 2.2e-75 252.6 0.2 4.1e-75 251.7 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAK64380.1 - 2.8e-30 104.8 0.3 2.8e-30 104.8 0.3 4.1 3 1 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 GAK64380.1 - 6.1e-17 61.6 0.4 1.9e-16 60.0 0.4 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 GAK64380.1 - 4.6e-06 26.3 0.1 2e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 GAK64380.1 - 4.3e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAK64380.1 - 0.00083 19.8 0.5 0.0033 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAK64380.1 - 0.0038 17.6 0.1 0.021 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAK64380.1 - 0.016 15.5 0.3 0.064 13.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 GAK64380.1 - 0.023 14.7 0.0 0.083 13.0 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 GAK64380.1 - 0.027 14.4 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 GAK64380.1 - 0.032 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 GAK64380.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 GAK64380.1 - 0.072 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 GAK64380.1 - 0.075 13.1 0.9 0.39 10.8 0.2 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAK64380.1 - 0.092 13.0 0.0 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 GAK64380.1 - 0.096 11.6 0.0 0.096 11.6 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 GAK64380.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SRPRB PF09439.10 GAK64380.1 - 0.13 11.6 0.4 4.5 6.7 0.1 2.4 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 GAK64380.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 GAK64380.1 - 0.17 11.1 0.4 5.6 6.2 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 ArsA_ATPase PF02374.15 GAK64380.1 - 0.32 10.1 3.8 6.6 5.8 0.1 3.0 2 1 1 3 3 3 0 Anion-transporting ATPase Peptidase_M13_N PF05649.13 GAK64382.1 - 3.5e-94 316.6 0.0 5e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAK64382.1 - 5.4e-57 192.7 0.0 8.7e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Cyclin_N PF00134.23 GAK64384.1 - 7.9e-14 51.5 0.1 1.7e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAK64384.1 - 1.3e-08 35.3 0.8 2.5e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin FBPase PF00316.20 GAK64386.1 - 4e-73 244.9 0.5 5.8e-73 244.4 0.5 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 GAK64386.1 - 0.0084 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family BTB PF00651.31 GAK64387.1 - 0.026 14.8 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain CwfJ_C_2 PF04676.14 GAK64388.1 - 3.6e-25 88.7 0.1 9.4e-25 87.4 0.1 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 GAK64388.1 - 4.1e-24 84.8 0.0 6.3e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Aconitase PF00330.20 GAK64389.1 - 7.2e-149 496.7 0.0 9.4e-149 496.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAK64389.1 - 4e-33 114.5 0.0 7.8e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.9 GAK64389.1 - 1.7e-05 25.0 1.4 0.0013 18.9 0.4 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 RdRP PF05183.12 GAK64390.1 - 4.3e-118 395.5 0.0 7.7e-118 394.7 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF5081 PF16887.5 GAK64390.1 - 0.16 11.0 0.1 0.29 10.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) Suf PF05843.14 GAK64390.1 - 3.4 7.6 5.9 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SAP PF02037.27 GAK64391.1 - 5.1e-05 22.9 0.3 0.00012 21.7 0.3 1.6 1 0 0 1 1 1 1 SAP domain Polysacc_deac_1 PF01522.21 GAK64392.1 - 7.3e-28 97.0 0.0 1.5e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase SSP160 PF06933.11 GAK64392.1 - 0.65 8.1 19.5 1 7.5 19.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 GAK64392.1 - 6.5 5.2 9.0 8.8 4.8 9.0 1.1 1 0 0 1 1 1 0 Macoilin family Zds_C PF08632.10 GAK64395.1 - 6.1e-27 93.1 1.9 6.1e-27 93.1 1.9 1.7 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Gti1_Pac2 PF09729.9 GAK64396.1 - 1.9e-34 119.3 4.6 2.9e-29 102.4 0.0 2.9 2 1 1 3 3 3 2 Gti1/Pac2 family Ran_BP1 PF00638.18 GAK64399.1 - 1.1e-17 64.4 1.2 2.2e-17 63.5 1.2 1.4 1 0 0 1 1 1 1 RanBP1 domain HAT PF02184.16 GAK64400.1 - 2.3e-17 62.6 58.5 8.9e-09 35.2 0.0 13.6 14 1 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 GAK64400.1 - 1.3e-12 46.8 8.6 0.012 15.6 0.1 9.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK64400.1 - 1.9e-11 43.8 49.8 0.0057 17.4 0.0 12.6 9 5 6 15 15 13 5 Tetratricopeptide repeat Suf PF05843.14 GAK64400.1 - 1.4e-10 41.7 28.9 0.0032 17.5 0.5 6.5 3 2 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 GAK64400.1 - 4.5e-10 39.9 15.0 0.0011 19.5 0.1 7.3 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAK64400.1 - 1.3e-07 31.5 0.1 0.00026 21.2 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAK64400.1 - 1.7e-07 30.8 0.3 0.54 10.2 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAK64400.1 - 7e-05 22.7 15.5 0.0077 16.4 0.1 7.7 8 1 2 10 10 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAK64400.1 - 0.00061 19.8 17.5 0.021 14.8 2.0 6.4 5 2 1 6 6 6 2 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 GAK64400.1 - 0.00077 19.5 11.6 1.7 8.8 0.0 6.8 4 3 2 7 7 7 1 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.6 GAK64400.1 - 0.00081 19.4 2.2 0.32 11.1 0.0 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat GCIP PF13324.6 GAK64400.1 - 0.098 12.2 2.7 0.2 11.2 2.7 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting MarB PF13999.6 GAK64400.1 - 0.21 11.5 1.6 0.46 10.4 1.6 1.5 1 0 0 1 1 1 0 MarB protein TPR_11 PF13414.6 GAK64400.1 - 0.77 9.5 5.4 5.7 6.7 0.0 4.7 6 0 0 6 6 6 0 TPR repeat TPR_7 PF13176.6 GAK64400.1 - 1 9.5 18.1 20 5.5 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK64400.1 - 7.3 7.5 0.0 7.3 7.5 0.0 9.0 11 1 0 11 11 8 0 Tetratricopeptide repeat SET PF00856.28 GAK64401.1 - 3.3e-19 69.9 0.0 3.3e-19 69.9 0.0 3.8 3 0 0 3 3 3 1 SET domain N-SET PF11764.8 GAK64401.1 - 6.3e-11 42.7 1.3 6.3e-11 42.7 1.3 5.8 4 3 1 5 5 5 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 GAK64401.1 - 3.1e-07 29.9 0.0 5.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Metallophos_2 PF12850.7 GAK64402.1 - 4.3e-20 72.6 0.1 6.5e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAK64402.1 - 0.00031 21.3 1.4 0.2 12.1 0.2 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase RNA_pol_Rpc4 PF05132.14 GAK64402.1 - 0.5 10.8 3.7 0.96 9.9 3.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 LSM PF01423.22 GAK64403.1 - 1.5e-14 53.4 0.1 1.9e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAK64403.1 - 0.037 13.7 0.0 0.068 12.8 0.0 1.6 1 1 0 1 1 1 0 Hfq protein Arf PF00025.21 GAK64404.1 - 2e-72 242.3 0.0 2.6e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAK64404.1 - 1.2e-14 54.5 0.0 2.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAK64404.1 - 1.6e-11 44.1 0.0 2.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAK64404.1 - 7.6e-11 41.8 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAK64404.1 - 9e-11 41.5 0.2 7.1e-06 25.4 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAK64404.1 - 4.1e-09 36.2 0.0 5.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK64404.1 - 0.00025 21.1 0.0 0.00056 20.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAK64405.1 - 1.4e-33 116.3 0.0 3.1e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAK64405.1 - 6.5e-32 111.3 14.1 1.2e-31 110.4 14.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAK64405.1 - 2.7e-05 23.7 0.1 0.00091 18.7 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAK64405.1 - 7.5e-05 23.2 0.2 7.5e-05 23.2 0.2 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAK64405.1 - 0.0014 18.9 0.1 0.014 15.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAK64405.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 GAK64405.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 GAK64405.1 - 0.021 14.6 0.0 0.085 12.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.6 GAK64405.1 - 0.032 14.0 0.0 0.07 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAK64405.1 - 0.033 13.9 0.1 0.098 12.4 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAK64405.1 - 0.035 14.5 0.0 0.32 11.4 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAK64405.1 - 0.04 13.2 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MTABC_N PF16185.5 GAK64405.1 - 0.14 11.6 5.1 0.19 11.2 0.0 3.3 4 1 0 4 4 4 0 Mitochondrial ABC-transporter N-terminal five TM region DUF2408 PF10303.9 GAK64406.1 - 1.1e-52 178.2 6.2 1.6e-38 132.3 0.0 4.5 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) STN1_2 PF09170.10 GAK64406.1 - 0.048 13.9 0.7 0.16 12.2 0.7 1.9 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 YabA PF06156.13 GAK64406.1 - 0.083 13.5 0.1 3.2 8.5 0.0 3.0 2 1 0 2 2 2 0 Initiation control protein YabA Imm5 PF14423.6 GAK64406.1 - 0.097 12.9 0.5 0.24 11.6 0.5 1.6 1 0 0 1 1 1 0 Immunity protein Imm5 Macoilin PF09726.9 GAK64406.1 - 0.11 11.0 1.9 0.25 9.9 1.9 1.5 1 0 0 1 1 1 0 Macoilin family DUF724 PF05266.14 GAK64406.1 - 0.14 12.0 2.2 0.27 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FlgN PF05130.12 GAK64406.1 - 4.2 7.9 6.7 23 5.5 0.0 3.4 3 0 0 3 3 3 0 FlgN protein BUD22 PF09073.10 GAK64406.1 - 8.4 5.6 10.8 16 4.7 4.5 2.3 2 0 0 2 2 2 0 BUD22 Copper-fist PF00649.18 GAK64407.1 - 1.8e-14 53.0 2.7 5.9e-14 51.3 2.7 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain RED_N PF07808.13 GAK64408.1 - 4.3e-11 42.9 3.0 6.7e-11 42.2 3.0 1.3 1 0 0 1 1 1 1 RED-like protein N-terminal region Phos_pyr_kin PF08543.12 GAK64409.1 - 4.4e-11 42.6 0.0 6.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 GAK64409.1 - 7.8e-08 32.0 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1690 PF07956.11 GAK64410.1 - 7.7e-30 104.1 6.2 9.8e-30 103.8 6.2 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) STAT_int PF02865.17 GAK64410.1 - 0.0082 16.6 0.3 0.031 14.7 0.1 1.9 1 1 1 2 2 2 1 STAT protein, protein interaction domain TolA_bind_tri PF16331.5 GAK64410.1 - 0.013 15.6 4.7 1.5 9.0 0.2 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF4407 PF14362.6 GAK64410.1 - 0.03 13.7 6.5 0.035 13.5 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5631 PF18645.1 GAK64410.1 - 0.041 14.3 0.1 0.16 12.3 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5631) Piwi PF02171.17 GAK64410.1 - 0.058 12.6 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Piwi domain FliT PF05400.13 GAK64410.1 - 0.19 12.6 4.2 11 6.9 1.6 2.4 2 0 0 2 2 2 0 Flagellar protein FliT Cep57_CLD_2 PF14197.6 GAK64410.1 - 0.44 10.7 5.3 10 6.3 0.9 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF737 PF05300.11 GAK64410.1 - 0.53 10.6 9.5 1 9.7 9.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Seryl_tRNA_N PF02403.22 GAK64410.1 - 0.7 10.1 8.3 0.12 12.7 4.7 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 GAK64410.1 - 1.1 8.1 2.7 1.2 7.9 2.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-N PF05238.13 GAK64411.1 - 1.5e-66 225.4 0.0 2e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Pinin_SDK_N PF04697.13 GAK64411.1 - 1.3 9.7 4.0 0.86 10.2 1.1 2.2 3 0 0 3 3 3 0 pinin/SDK conserved region ArgJ PF01960.18 GAK64412.1 - 3.2e-136 454.0 0.4 3.9e-136 453.7 0.4 1.0 1 0 0 1 1 1 1 ArgJ family Aminotran_1_2 PF00155.21 GAK64413.1 - 1e-30 107.1 0.0 1.3e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RPN6_N PF18055.1 GAK64414.1 - 8.2e-43 145.5 2.3 8.2e-43 145.5 2.3 2.5 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 GAK64414.1 - 1.7e-19 70.2 0.2 5.7e-19 68.6 0.2 1.9 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 GAK64414.1 - 5e-13 48.5 1.4 1e-12 47.5 1.4 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_16 PF13432.6 GAK64414.1 - 0.0032 18.1 8.2 1.4 9.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64414.1 - 0.085 13.1 2.6 0.28 11.4 0.1 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GAK64414.1 - 0.13 11.6 3.9 0.89 8.9 3.9 2.2 1 1 0 1 1 1 0 MalT-like TPR region TPR_7 PF13176.6 GAK64414.1 - 0.29 11.2 5.9 27 5.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK64414.1 - 2.1 9.2 4.3 14 6.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PEP-utilisers_N PF05524.13 GAK64414.1 - 4 7.7 6.5 0.7 10.1 0.2 3.0 4 0 0 4 4 4 0 PEP-utilising enzyme, N-terminal Aldo_ket_red PF00248.21 GAK64415.1 - 3e-32 112.0 0.0 7.4e-32 110.7 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family DUF21 PF01595.20 GAK64416.1 - 1.3e-36 125.9 0.3 2.3e-36 125.1 0.3 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAK64416.1 - 0.011 16.1 1.6 6.6 7.3 0.1 3.6 4 0 0 4 4 4 0 CBS domain DcpS_C PF11969.8 GAK64417.1 - 3.2e-12 47.0 2.9 6.6e-07 29.8 1.0 2.4 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 GAK64417.1 - 4e-12 46.4 0.0 9.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 GAK64417.1 - 4.2e-12 46.7 1.1 5.2e-06 27.1 0.2 2.4 2 0 0 2 2 2 2 HIT domain Sprouty PF05210.13 GAK64418.1 - 0.75 10.2 3.6 13 6.2 0.0 3.3 3 0 0 3 3 3 0 Sprouty protein (Spry) CoA_trans PF01144.23 GAK64419.1 - 3.1e-107 356.9 1.8 2.9e-64 216.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 GAK64419.1 - 0.00049 20.1 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DeoRC PF00455.22 GAK64419.1 - 0.051 13.5 0.0 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 DeoR C terminal sensor domain SUI1 PF01253.22 GAK64420.1 - 7.2e-26 90.5 2.0 1.3e-25 89.7 2.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 GATA PF00320.27 GAK64420.1 - 2e-13 49.7 3.7 3.8e-13 48.8 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 GAK64420.1 - 3.7e-08 33.6 0.0 5.5e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 GAK64420.1 - 1.3e-07 31.6 0.0 5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 GAK64420.1 - 3e-06 27.4 0.0 1.6e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 GAK64420.1 - 4.2e-06 27.0 0.0 1.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 GAK64420.1 - 0.00018 21.6 0.0 0.00046 20.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.12 GAK64420.1 - 0.2 11.2 0.6 0.65 9.6 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding UBX PF00789.20 GAK64421.1 - 4.2e-13 49.3 0.0 9.9e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 GAK64421.1 - 0.00026 21.1 0.0 0.00056 20.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DUF874 PF05917.11 GAK64421.1 - 1.2 8.1 4.2 1.9 7.4 4.2 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Cwf_Cwc_15 PF04889.12 GAK64421.1 - 1.6 8.4 16.1 1.4 8.6 1.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 GAK64422.1 - 2.8e-33 113.4 18.7 3.7e-06 27.6 0.1 11.4 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 GAK64422.1 - 2.4e-19 69.6 0.0 3.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAK64422.1 - 1e-16 61.0 0.0 0.0057 16.9 0.0 9.3 3 2 7 10 10 10 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK64422.1 - 3.8e-06 26.1 4.1 6.9 5.5 0.1 5.7 3 3 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAK64422.1 - 0.00097 17.8 0.1 1.1 7.7 0.0 3.2 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 GAK64422.1 - 0.0026 16.5 0.0 3.5 6.1 0.0 3.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 GAK64422.1 - 0.0091 15.4 0.0 0.75 9.1 0.0 2.9 3 0 0 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 GAK64422.1 - 0.0092 14.9 0.0 3.9 6.3 0.1 2.7 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 GAK64422.1 - 0.064 12.3 0.2 2.4 7.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) YjeF_N PF03853.15 GAK64424.1 - 7.5e-32 110.6 0.0 9.4e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus RabGAP-TBC PF00566.18 GAK64425.1 - 7.7e-33 114.0 2.8 2.3e-32 112.4 2.8 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 GAK64425.1 - 0.0012 18.3 0.0 0.18 11.2 0.0 2.6 2 1 0 2 2 2 2 Rab-binding domain (RBD) Cep57_MT_bd PF06657.13 GAK64426.1 - 2.4e-15 56.7 1.8 2.4e-15 56.7 1.8 3.6 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 PQQ_3 PF13570.6 GAK64427.1 - 0.0036 17.7 4.4 0.067 13.7 0.1 3.5 3 0 0 3 3 3 2 PQQ-like domain NMT PF01233.19 GAK64428.1 - 4.1e-74 247.8 0.0 6.2e-74 247.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 GAK64428.1 - 4.2e-73 245.3 0.0 2.3e-72 242.9 0.0 2.1 2 1 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 GAK64428.1 - 0.00033 20.7 0.0 0.00081 19.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK64428.1 - 0.0033 17.6 0.0 0.0084 16.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PBP1_TM PF14812.6 GAK64428.1 - 0.011 16.0 7.1 0.023 15.0 7.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 GAK64428.1 - 0.038 14.1 14.3 0.067 13.3 14.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SURF2 PF05477.11 GAK64428.1 - 0.55 9.9 13.1 0.04 13.6 7.9 1.6 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF2457 PF10446.9 GAK64428.1 - 0.89 8.6 15.5 1.4 8.0 15.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 GAK64428.1 - 1.2 8.4 12.2 2 7.6 12.2 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 GAK64428.1 - 1.2 9.1 5.6 2.9 7.9 5.6 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 GAK64428.1 - 1.7 8.3 5.0 4.3 7.0 5.0 1.7 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 GAK64428.1 - 1.8 9.0 14.3 5.3 7.5 14.1 1.8 2 0 0 2 2 1 0 Centromere protein B dimerisation domain TFIIF_alpha PF05793.12 GAK64428.1 - 2 6.9 18.2 3 6.3 18.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 GAK64428.1 - 2.6 6.2 9.0 3.9 5.7 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Rrp44_CSD1 PF17216.3 GAK64428.1 - 2.6 7.7 5.1 6 6.6 4.2 1.9 2 0 0 2 2 2 0 Rrp44-like cold shock domain DNA_pol_phi PF04931.13 GAK64428.1 - 3 5.8 11.1 4.7 5.2 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi PGA2 PF07543.12 GAK64428.1 - 7.1 6.6 13.1 0.2 11.6 6.4 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 RRN3 PF05327.11 GAK64428.1 - 8.6 4.8 6.9 16 3.9 6.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SOG2 PF10428.9 GAK64429.1 - 1.8e-159 532.2 1.4 1.8e-159 532.2 1.4 4.1 3 1 1 4 4 4 1 RAM signalling pathway protein LRR_8 PF13855.6 GAK64429.1 - 8e-16 57.6 8.2 3.5e-07 29.9 0.2 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAK64429.1 - 1.1e-12 47.9 6.7 5.1e-06 26.7 1.8 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAK64429.1 - 0.01 16.2 4.4 31 5.6 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 GAK64429.1 - 0.69 10.1 2.8 5 7.4 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat G-patch PF01585.23 GAK64430.1 - 7.4e-12 45.0 3.6 1.3e-11 44.2 3.6 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAK64430.1 - 6.1e-07 29.4 0.6 1.2e-06 28.5 0.6 1.4 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 GAK64430.1 - 0.038 13.6 1.0 0.68 9.5 0.0 2.4 2 0 0 2 2 2 0 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 GAK64430.1 - 0.084 13.2 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAK64430.1 - 0.1 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAK64430.1 - 0.14 13.1 0.2 0.28 12.1 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Auxin_repressed PF05564.12 GAK64430.1 - 0.16 12.6 9.6 0.096 13.4 2.3 3.0 3 0 0 3 3 3 0 Dormancy/auxin associated protein zf-C2H2 PF00096.26 GAK64430.1 - 0.17 12.4 0.1 0.35 11.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type SAM_2 PF07647.17 GAK64431.1 - 0.045 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glycos_transf_1 PF00534.20 GAK64432.1 - 2.6e-25 88.9 0.0 5.9e-25 87.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAK64432.1 - 8.3e-12 45.7 0.4 7.7e-11 42.6 0.2 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAK64432.1 - 2.2e-10 40.8 0.1 7.4e-10 39.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 GAK64432.1 - 9e-07 29.2 0.2 8.8e-06 26.0 0.0 2.8 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAK64432.1 - 0.011 16.2 2.5 0.012 16.1 0.1 2.4 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain SeqA_N PF17206.3 GAK64432.1 - 0.21 10.9 0.1 0.55 9.6 0.1 1.7 2 0 0 2 2 2 0 SeqA protein N-terminal domain FA_desaturase PF00487.24 GAK64434.1 - 2.4e-24 86.6 18.0 4.8e-24 85.6 18.0 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 GAK64434.1 - 1.4e-18 66.1 0.7 2.4e-18 65.3 0.7 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) WD40 PF00400.32 GAK64434.1 - 2.9e-16 59.6 4.9 4.5e-05 24.1 0.5 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64434.1 - 6.2e-06 26.4 0.0 2.4 8.5 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Peroxin-3 PF04882.12 GAK64434.1 - 0.0034 16.4 0.4 0.0054 15.8 0.4 1.2 1 0 0 1 1 1 1 Peroxin-3 Nucleo_LEF-12 PF06256.11 GAK64434.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein Zn_clus PF00172.18 GAK64435.1 - 1.7e-05 24.8 10.2 2.8e-05 24.2 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK64435.1 - 0.00023 20.3 0.2 0.00048 19.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2407_C PF13373.6 GAK64436.1 - 6.8e-13 49.0 8.5 7.9e-13 48.8 1.9 3.5 3 1 0 3 3 3 1 DUF2407 C-terminal domain DUF2407 PF10302.9 GAK64436.1 - 8.7e-07 29.5 1.1 0.0001 22.8 0.2 3.3 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAK64436.1 - 0.0034 17.1 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family ChaC PF04752.12 GAK64438.1 - 1.1e-51 175.4 0.0 2.1e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.31 GAK64438.1 - 3.9e-25 87.7 4.1 1.1e-24 86.3 4.1 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 GAK64438.1 - 1.4e-10 41.1 3.0 1.4e-08 34.8 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAK64438.1 - 8.4e-08 32.4 2.8 3e-06 27.4 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAK64438.1 - 3.4e-06 27.3 0.2 0.016 15.5 0.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAK64438.1 - 0.0026 18.5 1.4 0.52 11.3 0.1 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 GAK64438.1 - 0.0059 17.0 2.9 0.46 11.0 0.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type LUC7 PF03194.15 GAK64439.1 - 3e-70 236.8 1.1 3e-70 236.8 1.1 1.7 2 0 0 2 2 2 1 LUC7 N_terminus DIM1 PF02966.16 GAK64439.1 - 4.3e-64 214.2 0.1 6.8e-64 213.6 0.1 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 Nitroreductase PF00881.24 GAK64440.1 - 8.3e-09 35.7 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family COX6B PF02297.17 GAK64441.1 - 3e-15 56.2 4.2 3e-15 56.2 4.2 1.6 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 GAK64441.1 - 0.057 13.4 0.5 0.086 12.8 0.5 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain CHCH PF06747.13 GAK64441.1 - 0.21 11.8 2.4 1.4 9.1 0.5 2.6 2 1 0 2 2 2 0 CHCH domain Prp18 PF02840.15 GAK64442.1 - 2.2e-61 206.1 0.0 4.1e-61 205.2 0.0 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 GAK64442.1 - 3.8e-11 42.3 6.2 9.7e-11 41.0 6.2 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like BNIP3 PF06553.12 GAK64442.1 - 0.54 9.9 6.5 1 9.0 6.5 1.4 1 0 0 1 1 1 0 BNIP3 Pex2_Pex12 PF04757.14 GAK64443.1 - 6e-43 147.0 1.4 7.6e-43 146.7 1.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 GAK64443.1 - 0.00012 22.3 3.3 0.00019 21.7 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAK64443.1 - 0.0013 18.9 3.0 0.0025 18.0 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAK64443.1 - 0.0022 17.7 2.7 0.0034 17.1 2.7 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAK64443.1 - 0.0067 16.4 2.3 0.012 15.6 2.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAK64443.1 - 0.029 14.2 2.4 0.051 13.4 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK64443.1 - 0.078 12.9 2.0 0.13 12.1 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.6 GAK64444.1 - 1.2e-10 41.0 0.1 2.3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAK64444.1 - 1.3e-07 31.0 0.0 2.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAK64444.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 GAK64444.1 - 0.0043 17.2 1.2 0.015 15.4 1.2 1.9 1 0 0 1 1 1 1 Podoplanin DUF3431 PF11913.8 GAK64444.1 - 0.005 16.6 2.1 0.0079 16.0 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) USP7_ICP0_bdg PF12436.8 GAK64446.1 - 1.6e-86 289.5 3.0 2.2e-86 289.1 1.4 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 GAK64446.1 - 4.6e-64 215.9 2.4 7.7e-63 211.9 1.1 2.6 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 GAK64446.1 - 7.5e-50 169.8 0.0 1.3e-49 169.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK64446.1 - 6.1e-21 75.3 0.0 1.3e-20 74.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GAK64446.1 - 9.1e-09 35.5 0.0 1.2e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 MATH domain Rad60-SLD PF11976.8 GAK64446.1 - 0.053 13.4 0.1 0.84 9.5 0.0 3.0 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like EF_assoc_1 PF08355.12 GAK64448.1 - 1.1e-32 111.4 0.1 9.8e-32 108.4 0.0 2.3 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 GAK64448.1 - 4.6e-31 107.6 0.0 3.9e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.12 GAK64448.1 - 4.5e-28 97.1 0.0 6.1e-27 93.5 0.0 2.4 1 1 0 1 1 1 1 EF hand associated Roc PF08477.13 GAK64448.1 - 1.2e-17 64.2 0.0 6.5e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAK64448.1 - 9.2e-09 35.4 0.0 5.7e-05 23.2 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 GAK64448.1 - 9.9e-09 34.1 2.0 0.0037 16.7 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAK64448.1 - 1.8e-08 34.7 0.4 0.0061 17.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAK64448.1 - 1.2e-07 31.1 2.8 0.0058 16.5 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain Arf PF00025.21 GAK64448.1 - 1.2e-05 24.8 0.0 0.059 12.8 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_5 PF13202.6 GAK64448.1 - 9e-05 21.8 4.2 0.05 13.1 0.5 2.6 2 0 0 2 2 2 2 EF hand AAA_18 PF13238.6 GAK64448.1 - 0.00015 22.3 0.0 0.022 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 GAK64448.1 - 0.00025 20.5 0.0 0.67 9.4 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 GAK64448.1 - 0.00033 20.9 0.0 0.81 10.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAK64448.1 - 0.0028 17.6 0.1 0.77 9.6 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 GAK64448.1 - 0.0044 16.6 0.0 1.5 8.3 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 GAK64448.1 - 0.0058 16.4 0.2 0.54 10.1 0.1 2.5 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) PduV-EutP PF10662.9 GAK64448.1 - 0.0071 16.1 0.0 0.21 11.3 0.0 2.6 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GAK64448.1 - 0.0077 16.6 0.0 3.4 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GAK64448.1 - 0.0096 15.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 GAK64448.1 - 0.012 15.2 0.0 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 GAK64448.1 - 0.018 14.9 1.0 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair AAA_19 PF13245.6 GAK64448.1 - 0.018 15.4 0.0 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAK64448.1 - 0.018 14.8 0.0 0.91 9.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 GAK64448.1 - 0.025 14.6 0.2 7.2 6.6 0.0 2.6 2 1 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 GAK64448.1 - 0.026 14.3 0.5 10 5.8 0.0 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 GAK64448.1 - 0.041 14.1 0.0 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAK64448.1 - 0.047 13.5 0.1 5.5 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 GAK64448.1 - 0.048 13.4 0.1 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.9 GAK64448.1 - 0.049 14.0 0.8 6.2 7.2 0.0 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_33 PF13671.6 GAK64448.1 - 0.055 13.6 0.1 2.8 8.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAK64448.1 - 0.057 12.6 0.2 0.29 10.3 0.1 2.0 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 GAK64448.1 - 0.076 12.4 0.5 2 7.7 0.1 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAK64448.1 - 0.083 13.3 0.0 5.9 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 GAK64448.1 - 0.085 12.6 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAK64448.1 - 0.096 13.1 0.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 GAK64448.1 - 0.096 12.2 0.1 0.49 9.9 0.0 2.2 3 0 0 3 3 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 GAK64448.1 - 0.12 12.9 0.0 24 5.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.9 GAK64448.1 - 0.12 11.5 0.1 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 EF-hand_10 PF14788.6 GAK64448.1 - 0.13 12.2 2.8 0.27 11.1 0.3 2.3 2 0 0 2 2 2 0 EF hand AAA_7 PF12775.7 GAK64448.1 - 0.13 11.7 0.1 5.2 6.6 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 GAK64448.1 - 0.14 11.7 0.4 4.7 6.8 0.0 3.0 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAK64448.1 - 0.15 11.3 0.0 4.5 6.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 GAK64448.1 - 0.2 11.5 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 GAK64448.1 - 0.22 11.4 0.7 3.4 7.5 0.0 2.6 2 1 1 3 3 3 0 NTPase MCM PF00493.23 GAK64448.1 - 0.26 10.4 0.2 0.77 8.8 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain Septin PF00735.18 GAK64448.1 - 0.26 10.5 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Septin LsmAD PF06741.13 GAK64449.1 - 6e-28 97.2 1.2 6e-28 97.2 1.2 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 GAK64449.1 - 4.1e-19 68.5 0.0 7.3e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain HSD3 PF15244.6 GAK64449.1 - 1.4 8.4 4.6 2.8 7.3 4.6 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 NAD_binding_4 PF07993.12 GAK64450.1 - 1.5e-28 99.6 0.0 2.5e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAK64450.1 - 2.8e-23 82.2 0.0 4.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAK64450.1 - 0.00024 21.4 0.0 0.0006 20.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 GAK64450.1 - 0.032 14.2 2.3 0.22 11.4 2.3 2.2 1 1 0 1 1 1 0 KR domain AMP-binding_C PF13193.6 GAK64450.1 - 0.22 12.6 0.4 0.88 10.6 0.1 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Aminotran_5 PF00266.19 GAK64453.1 - 3.9e-31 108.3 0.0 5.6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V HAD_2 PF13419.6 GAK64454.1 - 7.3e-11 42.5 0.0 1.7e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAK64454.1 - 4.4e-06 26.7 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like zf-C3HC4 PF00097.25 GAK64455.1 - 2.1e-09 37.1 2.6 5.3e-09 35.8 2.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK64455.1 - 1e-07 31.9 3.8 1e-07 31.9 3.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAK64455.1 - 1.2e-07 32.0 3.1 4.6e-06 26.8 1.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAK64455.1 - 2.2e-07 30.6 5.3 1.1e-06 28.4 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK64455.1 - 5.5e-06 26.2 3.4 9.7e-06 25.4 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAK64455.1 - 0.00011 22.3 3.6 0.00011 22.3 3.6 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAK64455.1 - 0.00064 19.5 7.8 0.0034 17.2 7.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 GAK64455.1 - 0.084 13.0 0.4 0.17 12.0 0.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.8 GAK64455.1 - 0.15 11.9 3.5 0.33 10.8 3.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zwint PF15556.6 GAK64455.1 - 0.18 11.3 7.4 2.1 7.8 1.0 2.4 2 0 0 2 2 2 0 ZW10 interactor Prok-RING_4 PF14447.6 GAK64455.1 - 0.33 10.9 6.9 0.75 9.7 3.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAK64455.1 - 0.58 10.5 4.7 1.8 8.9 4.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAK64455.1 - 0.93 9.3 6.7 0.93 9.3 4.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger Gly_transf_sug PF04488.15 GAK64456.1 - 4.9e-06 27.1 0.1 9.8e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SSF PF00474.17 GAK64457.1 - 2.1e-18 66.4 20.4 2.1e-18 66.4 20.4 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family K_oxygenase PF13434.6 GAK64458.1 - 3.9e-10 39.4 0.0 6.2e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAK64458.1 - 7e-07 28.8 0.0 0.0061 15.8 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAK64458.1 - 4.9e-05 23.4 1.2 0.5 10.3 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAK64458.1 - 0.00053 19.3 0.1 0.0022 17.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAK64458.1 - 0.0035 17.0 4.3 0.0051 16.4 0.0 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAK64458.1 - 0.0083 15.4 0.6 0.23 10.7 0.0 2.9 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAK64458.1 - 0.039 13.0 4.1 0.67 8.9 0.1 3.1 4 1 0 4 4 4 0 Lycopene cyclase protein HI0933_like PF03486.14 GAK64458.1 - 0.14 10.8 0.1 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein RNA_pol_Rpb1_5 PF04998.17 GAK64460.1 - 5.7e-87 291.5 0.0 1.2e-86 290.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAK64460.1 - 1.8e-63 213.7 0.1 3.7e-63 212.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAK64460.1 - 6.9e-37 126.8 0.0 1.3e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 GAK64460.1 - 2.9e-28 99.1 0.4 3.9e-22 79.0 0.0 4.4 5 0 0 5 5 5 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 GAK64460.1 - 1.8e-23 82.5 0.0 9.5e-23 80.2 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Med21 PF11221.8 GAK64460.1 - 0.7 10.1 2.8 11 6.3 1.2 3.4 3 0 0 3 3 3 0 Subunit 21 of Mediator complex CDC45 PF02724.14 GAK64461.1 - 0.45 8.8 2.8 0.5 8.6 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 GAK64461.1 - 4 7.6 9.0 71 3.6 9.1 2.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhodopsin PF01036.18 GAK64462.1 - 1e-49 169.1 15.3 1.5e-49 168.6 15.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arteri_Gl PF00951.18 GAK64462.1 - 0.31 10.9 6.7 0.11 12.3 2.5 2.1 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF3810 PF12725.7 GAK64462.1 - 0.55 9.5 5.2 0.26 10.6 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2754 PF10953.8 GAK64462.1 - 1.4 9.2 7.5 4 7.7 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) DUF4743 PF15916.5 GAK64464.1 - 2.9e-12 46.6 0.0 5.4e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) NUDIX PF00293.28 GAK64464.1 - 8.4e-11 42.0 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HEAT_EZ PF13513.6 GAK64464.1 - 1.9 9.1 10.7 6.5 7.4 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat MCM_bind PF09739.9 GAK64465.1 - 1.2e-83 281.6 0.0 7.8e-69 232.6 0.0 2.2 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor Ala_racemase_N PF01168.20 GAK64465.1 - 2.3e-16 60.1 0.3 3.8e-15 56.1 0.0 2.8 2 1 0 2 2 2 1 Alanine racemase, N-terminal domain CS PF04969.16 GAK64466.1 - 1.1e-19 71.2 0.3 2.1e-19 70.3 0.3 1.5 1 0 0 1 1 1 1 CS domain Integrase_1 PF12835.7 GAK64466.1 - 0.0093 16.1 0.2 0.015 15.4 0.2 1.3 1 0 0 1 1 1 1 Integrase SieB PF14163.6 GAK64466.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Metal_resist PF13801.6 GAK64466.1 - 2 8.6 8.3 6.3 7.0 1.5 2.2 2 0 0 2 2 2 0 Heavy-metal resistance 6PF2K PF01591.18 GAK64467.1 - 3.1e-71 239.2 0.0 5e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAK64467.1 - 3.3e-33 115.0 0.0 1.5e-32 112.9 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAK64467.1 - 8.4e-08 32.5 0.0 2.7e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAK64467.1 - 0.022 14.2 0.2 0.099 12.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SelP_N PF04592.14 GAK64467.1 - 1.3 8.4 12.0 2.9 7.2 12.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CAF20 PF17052.5 GAK64467.1 - 3 8.0 5.9 0.31 11.2 1.2 1.7 2 0 0 2 2 2 0 Cap associated factor RCC1 PF00415.18 GAK64468.1 - 2.1e-19 69.9 2.5 0.0015 19.1 0.0 6.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAK64468.1 - 1.8e-18 66.8 0.0 1.8e-08 34.6 0.0 3.5 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.6 GAK64468.1 - 5.9e-08 32.8 0.6 3.3e-06 27.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAK64468.1 - 9.7e-08 32.4 0.2 3.3e-07 30.7 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 GAK64468.1 - 3.5e-07 29.8 19.2 0.0016 18.2 0.0 6.4 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.30 GAK64468.1 - 6.7e-05 23.2 1.0 0.3 11.6 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GAK64468.1 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAK64468.1 - 0.0023 18.3 0.7 2.4 9.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Bromodomain PF00439.25 GAK64470.1 - 2.7e-52 174.8 0.3 5.1e-18 64.9 0.1 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 GAK64470.1 - 1.9e-05 24.3 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 GAK64470.1 - 0.00024 21.4 6.5 0.11 12.9 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats FBA_2 PF07735.17 GAK64470.1 - 0.2 11.8 0.0 0.57 10.3 0.0 1.7 1 0 0 1 1 1 0 F-box associated SKIP_SNW PF02731.15 GAK64471.1 - 8.9e-68 227.0 2.9 8.9e-68 227.0 2.9 2.1 3 0 0 3 3 3 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 GAK64471.1 - 0.0043 16.8 12.5 0.0043 16.8 12.5 1.8 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Dynamin_M PF01031.20 GAK64472.1 - 1.5e-102 342.7 0.0 3.3e-101 338.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 GAK64472.1 - 6.8e-54 182.4 0.0 1.2e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAK64472.1 - 3.2e-25 88.1 5.6 3.2e-25 88.1 5.6 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAK64472.1 - 0.0004 20.4 0.1 0.0021 18.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAK64472.1 - 0.12 12.8 0.0 0.53 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Calreticulin PF00262.18 GAK64473.1 - 6.6e-165 548.4 7.6 8e-165 548.1 7.6 1.1 1 0 0 1 1 1 1 Calreticulin family NTF2 PF02136.20 GAK64474.1 - 1.1e-34 119.5 0.3 1.3e-34 119.3 0.3 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 GAK64474.1 - 0.0094 16.3 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Imm58 PF15581.6 GAK64474.1 - 0.063 13.4 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 58 SnoaL_4 PF13577.6 GAK64474.1 - 0.064 13.4 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF3402 PF11882.8 GAK64475.1 - 2.6e-122 409.3 0.8 1.5e-121 406.8 0.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 GAK64475.1 - 1.2e-60 205.1 0.0 1.9e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein MFS_1 PF07690.16 GAK64476.1 - 1e-47 162.8 38.1 1.4e-47 162.3 38.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2613 PF11021.8 GAK64477.1 - 0.041 14.0 0.4 0.041 14.0 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Antimicrobial11 PF08106.11 GAK64477.1 - 0.9 9.7 4.1 19 5.5 0.3 3.0 1 1 1 2 2 2 0 Formaecin family Sigma_reg_N PF13800.6 GAK64477.1 - 7.8 6.9 12.2 0.55 10.6 2.2 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal HK PF02110.15 GAK64478.1 - 2.8e-62 210.3 3.5 3.3e-59 200.2 3.3 2.3 1 1 1 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 GAK64478.1 - 7.3e-45 152.5 0.1 1.8e-44 151.3 0.0 1.7 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 GAK64478.1 - 0.00018 20.9 0.1 0.00034 20.1 0.1 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase tRNA-synt_1e PF01406.19 GAK64479.1 - 1.2e-122 409.1 0.0 1.7e-122 408.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAK64479.1 - 2.4e-09 36.4 0.5 5.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAK64479.1 - 0.00046 18.6 0.0 0.075 11.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 GAK64479.1 - 0.00089 19.7 1.2 0.0021 18.5 0.0 2.3 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.21 GAK64479.1 - 0.0054 15.7 1.0 0.014 14.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 GAK64479.1 - 0.078 11.9 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) Sec1 PF00995.23 GAK64480.1 - 3.9e-114 383.0 0.0 4.4e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ribonuclease_T2 PF00445.18 GAK64481.1 - 4.4e-38 131.3 0.3 6e-38 130.9 0.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family GST_C_2 PF13410.6 GAK64482.1 - 3e-10 40.0 0.0 7.1e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAK64482.1 - 0.00034 21.0 0.0 0.0008 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAK64482.1 - 0.00054 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAK64482.1 - 0.0088 16.2 0.0 0.022 15.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAK64482.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 GAK64483.1 - 1.6e-15 56.7 0.0 2.2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK64483.1 - 8.1e-06 25.4 0.0 9.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GAK64483.1 - 0.00023 21.3 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 RRM-like domain THF_DHG_CYH PF00763.23 GAK64484.1 - 8.5e-26 90.5 0.0 1.5e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAK64484.1 - 4.4e-15 55.4 0.0 8.1e-08 31.7 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 GAK64484.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family SNF2_N PF00176.23 GAK64485.1 - 2.3e-76 256.8 0.0 4e-76 256.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAK64485.1 - 9.2e-39 132.0 0.5 4.3e-38 129.8 0.1 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 GAK64485.1 - 3.9e-35 120.9 0.7 3.9e-35 120.9 0.7 3.7 2 1 1 3 3 2 1 HAND Helicase_C PF00271.31 GAK64485.1 - 1.1e-20 74.0 0.0 4.2e-18 65.7 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK64485.1 - 3.4e-12 46.7 0.1 6.1e-11 42.6 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAK64485.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAK64485.1 - 5.4e-05 22.5 0.0 0.00016 21.0 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 GAK64485.1 - 0.00025 21.2 5.1 0.0042 17.2 0.0 3.2 3 0 0 3 3 2 1 Myb-like DNA-binding domain DUF1086 PF06461.11 GAK64485.1 - 0.0021 17.9 0.1 0.0081 16.0 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 GAK64485.1 - 0.006 16.6 0.0 0.022 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 GAK64485.1 - 0.0074 15.5 7.8 0.033 13.4 0.0 2.6 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DBINO PF13892.6 GAK64485.1 - 0.012 15.9 4.1 0.012 15.9 4.1 4.3 4 0 0 4 4 4 0 DNA-binding domain AAA_22 PF13401.6 GAK64485.1 - 5 7.4 5.9 0.81 10.0 0.0 2.8 3 1 0 3 3 3 0 AAA domain Telomere_reg-2 PF10193.9 GAK64486.1 - 1.6e-26 92.9 0.1 8.5e-26 90.5 0.0 2.4 3 0 0 3 3 3 1 Telomere length regulation protein DprA_WH PF17782.1 GAK64486.1 - 0.09 12.9 3.0 0.95 9.6 0.4 3.7 3 0 0 3 3 3 0 DprA winged helix domain MCD_N PF17408.2 GAK64486.1 - 0.15 12.2 0.2 0.48 10.6 0.2 1.9 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain PHD PF00628.29 GAK64487.1 - 1.4e-06 28.1 10.6 2.3e-06 27.4 10.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAK64487.1 - 0.0011 18.4 7.2 0.0021 17.6 7.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 GAK64487.1 - 0.015 15.3 4.2 0.036 14.1 4.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Anillin_N PF16018.5 GAK64487.1 - 0.54 10.9 6.6 0.13 12.9 1.2 2.9 2 0 0 2 2 2 0 Anillin N-terminus HMMR_N PF15905.5 GAK64488.1 - 0.0016 18.0 141.5 0.039 13.4 10.9 7.1 3 2 3 6 6 6 5 Hyaluronan mediated motility receptor N-terminal Tropomyosin PF00261.20 GAK64488.1 - 0.0018 17.7 8.7 0.0018 17.7 8.7 9.9 3 3 5 8 8 8 1 Tropomyosin Mto2_bdg PF12808.7 GAK64488.1 - 0.0037 17.5 11.0 0.0037 17.5 11.0 10.0 10 2 0 10 10 10 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Leu_zip PF15294.6 GAK64488.1 - 0.0053 16.3 14.9 0.0053 16.3 14.9 8.2 3 2 5 8 8 8 2 Leucine zipper HIP1_clath_bdg PF16515.5 GAK64488.1 - 0.015 15.9 6.7 0.015 15.9 6.7 13.9 4 3 8 14 14 14 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 GAK64488.1 - 1 8.2 153.6 0.0081 15.1 13.7 8.6 3 2 6 9 9 9 0 Spc7 kinetochore protein LMSTEN PF07988.12 GAK64488.1 - 1.2 8.6 7.6 2.3 7.7 0.2 3.6 3 0 0 3 3 3 0 LMSTEN motif AAA_13 PF13166.6 GAK64488.1 - 1.7 7.2 110.5 0.61 8.7 11.4 5.1 3 1 2 5 5 5 0 AAA domain Zn_clus PF00172.18 GAK64489.1 - 9.9e-08 32.0 7.8 1.6e-07 31.3 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK64489.1 - 1.3e-07 30.9 2.8 7.4e-07 28.5 0.0 2.9 3 1 1 4 4 4 1 Fungal specific transcription factor domain Peptidase_M16_C PF05193.21 GAK64491.1 - 4.6e-44 150.6 0.0 9.7e-44 149.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAK64491.1 - 3.5e-41 140.7 0.0 7.8e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) TRPM_tetra PF16519.5 GAK64491.1 - 0.73 10.0 3.0 9.1 6.5 0.2 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM SOG2 PF10428.9 GAK64491.1 - 0.75 8.9 22.1 0.45 9.7 1.5 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Hydrolase_4 PF12146.8 GAK64492.1 - 1.1e-29 103.4 0.2 3.2e-29 101.9 0.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK64492.1 - 8e-09 36.4 0.6 1.9e-08 35.2 0.6 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAK64492.1 - 1.4e-07 31.4 0.2 0.00015 21.5 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 GAK64492.1 - 0.0072 15.9 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 GAK64492.1 - 0.011 15.4 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Putative esterase MFS_1 PF07690.16 GAK64493.1 - 1.2e-35 123.1 53.2 1.2e-35 123.1 53.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK64493.1 - 7.9e-14 51.4 7.5 7.9e-14 51.4 7.5 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter DUF2516 PF10724.9 GAK64493.1 - 2.7 8.3 6.1 1 9.7 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) Asp PF00026.23 GAK64494.1 - 7.7e-70 235.8 0.3 9.9e-70 235.4 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK64494.1 - 3.3e-12 47.0 0.4 4.3e-05 23.8 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAK64494.1 - 1.3e-05 25.7 1.2 0.033 14.8 0.0 3.5 2 1 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GAK64494.1 - 3.6e-05 24.3 0.2 0.012 16.1 0.0 3.1 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Syja_N PF02383.18 GAK64496.1 - 1.9e-74 250.8 0.0 2.8e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 GAK64496.1 - 9.8e-11 41.6 0.0 2.3e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family F-box-like PF12937.7 GAK64497.1 - 1.3e-09 37.8 0.9 1.3e-09 37.8 0.9 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAK64497.1 - 1.7e-05 24.6 0.0 8.2e-05 22.4 0.0 2.2 1 0 0 1 1 1 1 F-box domain ATP_synt_H PF05493.13 GAK64498.1 - 1.8e-21 76.3 3.7 2.2e-21 76.1 3.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit H NAD_binding_2 PF03446.15 GAK64499.1 - 1.6e-18 67.3 0.0 2.8e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAK64499.1 - 7e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 GAK64499.1 - 9.4e-07 29.0 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAK64499.1 - 7.5e-05 23.2 0.0 0.0003 21.3 0.0 2.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAK64499.1 - 0.12 12.8 0.0 0.67 10.4 0.0 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Rad21_Rec8_N PF04825.13 GAK64500.1 - 1.5e-38 131.3 0.2 2.9e-38 130.4 0.2 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAK64500.1 - 1.8e-16 59.2 0.0 5.1e-16 57.7 0.0 1.9 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SIP1 PF04938.12 GAK64500.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF1467 PF07330.12 GAK64502.1 - 0.13 12.3 0.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) Cyclin_N PF00134.23 GAK64504.1 - 4.5e-44 149.3 0.2 1.3e-41 141.3 0.4 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAK64504.1 - 1.1e-26 93.2 0.0 1.1e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-MYND PF01753.18 GAK64506.1 - 1.9e-06 27.8 15.8 4.9e-06 26.5 15.8 1.7 1 0 0 1 1 1 1 MYND finger CLPTM1 PF05602.12 GAK64507.1 - 5.8e-110 368.3 0.0 2.7e-108 362.8 0.0 2.1 2 0 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 GAK64507.1 - 2.6e-05 23.9 0.7 0.00011 21.9 0.5 2.2 2 0 0 2 2 2 1 PQ loop repeat MFS_1 PF07690.16 GAK64508.1 - 2.2e-27 95.9 30.4 2.2e-27 95.9 30.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK64508.1 - 1.7e-10 40.4 5.2 1.7e-10 40.4 5.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter AMP-binding PF00501.28 GAK64510.1 - 1e-71 241.8 0.0 1.3e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK64510.1 - 0.00097 20.1 0.2 0.0021 19.0 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PLU-1 PF08429.11 GAK64511.1 - 2.9e-88 296.3 1.2 6.1e-87 292.0 0.7 2.4 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 GAK64511.1 - 7.7e-43 145.6 0.4 1.6e-42 144.6 0.4 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 GAK64511.1 - 3.4e-26 90.9 37.4 9.3e-13 47.9 3.2 4.4 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 GAK64511.1 - 2.2e-18 66.7 0.0 5.6e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 GAK64511.1 - 3.8e-13 49.2 1.3 7e-13 48.3 1.3 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 GAK64511.1 - 4.1e-10 39.9 0.2 4.1e-10 39.9 0.2 3.0 4 0 0 4 4 2 1 C5HC2 zinc finger zf-HC5HC2H PF13771.6 GAK64511.1 - 0.0012 19.1 10.6 1.1 9.5 0.2 3.5 3 0 0 3 3 3 3 PHD-like zinc-binding domain PHD_2 PF13831.6 GAK64511.1 - 0.0039 16.7 26.1 0.017 14.7 2.8 3.9 4 0 0 4 4 4 2 PHD-finger Fe-ADH_2 PF13685.6 GAK64511.1 - 0.013 15.2 0.2 0.033 13.9 0.2 1.6 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase TusA PF01206.17 GAK64511.1 - 0.08 12.8 0.2 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 Sulfurtransferase TusA zf-HC5HC2H_2 PF13832.6 GAK64511.1 - 0.25 11.5 10.3 3.7 7.7 0.4 3.4 3 0 0 3 3 3 0 PHD-zinc-finger like domain C1_1 PF00130.22 GAK64511.1 - 0.61 10.0 23.9 0.76 9.7 1.4 4.3 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 GAK64511.1 - 9.1 6.5 17.3 0.048 13.8 0.3 3.8 3 0 0 3 3 3 0 KIAA1045 RING finger E1-E2_ATPase PF00122.20 GAK64512.1 - 4.3e-41 140.4 1.3 2.1e-38 131.7 0.0 3.4 3 1 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 GAK64512.1 - 1.5e-18 67.8 0.6 3.5e-18 66.6 0.6 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK64512.1 - 4.4e-10 39.1 0.0 8.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAK64512.1 - 0.0018 18.1 0.3 0.0039 17.0 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YrvL PF14184.6 GAK64512.1 - 0.0041 17.2 4.2 0.0041 17.2 4.2 2.4 2 0 0 2 2 2 1 Regulatory protein YrvL Cation_ATPase PF13246.6 GAK64512.1 - 0.096 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Methyltransf_16 PF10294.9 GAK64513.1 - 1.5e-14 54.1 0.0 1.1e-13 51.3 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAK64513.1 - 0.046 13.3 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RPA_C PF08784.11 GAK64515.1 - 3.1e-16 59.9 1.6 3.5e-16 59.7 0.6 1.6 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 GAK64515.1 - 1.7e-08 34.3 0.1 2.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 GAK64515.1 - 0.044 13.6 0.3 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 DUF1204 PF06721.11 GAK64515.1 - 0.045 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Het-C PF07217.11 GAK64516.1 - 1.3e-218 727.2 0.0 2.2e-218 726.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C OrfB_Zn_ribbon PF07282.11 GAK64516.1 - 0.03 14.2 0.3 0.086 12.8 0.3 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain 6PGD PF00393.19 GAK64517.1 - 7.5e-127 422.6 0.0 1.7e-126 421.5 0.0 1.6 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAK64517.1 - 3e-52 177.0 0.0 6.8e-52 175.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAK64517.1 - 0.029 14.9 0.1 0.065 13.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoatB PF10389.9 GAK64517.1 - 0.17 11.8 0.9 0.97 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B Sterol-sensing PF12349.8 GAK64518.1 - 6.6e-49 165.7 10.8 1.1e-48 164.9 10.8 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAK64518.1 - 4.5e-16 58.1 5.4 6.3e-16 57.6 5.4 1.1 1 0 0 1 1 1 1 Patched family ANAPC4_WD40 PF12894.7 GAK64518.1 - 0.0031 17.8 0.0 1.9 8.8 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK64518.1 - 0.03 13.0 0.3 0.054 12.1 0.3 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.32 GAK64518.1 - 0.032 15.1 1.2 0.68 10.9 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat ADH_zinc_N PF00107.26 GAK64519.1 - 1.8e-08 34.4 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK64519.1 - 6e-07 29.3 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAK64519.1 - 0.028 15.5 0.0 0.066 14.3 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAK64519.1 - 0.06 13.2 0.1 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase JmjC PF02373.22 GAK64520.1 - 1.3e-09 38.4 0.0 3.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase 2OG-FeII_Oxy_5 PF13759.6 GAK64520.1 - 0.062 13.7 0.0 0.27 11.7 0.0 2.1 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CorA PF01544.18 GAK64520.1 - 6 6.1 7.2 11 5.3 7.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PseudoU_synth_1 PF01416.20 GAK64522.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase UFD1 PF03152.14 GAK64523.1 - 2.9e-68 228.7 0.0 3.8e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cpn60_TCP1 PF00118.24 GAK64524.1 - 2.8e-147 491.3 18.5 5.5e-147 490.3 18.5 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chitin_synth_2 PF03142.15 GAK64526.1 - 7.7e-293 971.9 0.0 9.6e-293 971.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAK64526.1 - 2.3e-11 44.0 1.2 7e-11 42.4 1.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK64526.1 - 2.7e-11 43.8 0.0 6.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAK64526.1 - 4.1e-05 23.1 0.0 0.0046 16.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAK64526.1 - 0.0029 17.4 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 ABC_membrane PF00664.23 GAK64527.1 - 1.2e-78 264.6 22.4 3.7e-40 138.3 5.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK64527.1 - 6.9e-51 172.4 0.1 2.6e-31 108.9 0.1 2.9 2 1 0 2 2 2 2 ABC transporter MTABC_N PF16185.5 GAK64527.1 - 9.2e-06 25.3 0.1 3.2e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region MMR_HSR1 PF01926.23 GAK64527.1 - 3.3e-05 23.9 0.5 0.16 12.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 GAK64527.1 - 4.1e-05 23.1 0.1 1.1 8.6 0.0 3.9 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 GAK64527.1 - 0.00012 22.2 2.1 0.34 11.0 0.2 2.8 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 GAK64527.1 - 0.00032 21.1 3.4 0.069 13.5 0.5 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAK64527.1 - 0.001 19.0 0.1 0.82 9.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 GAK64527.1 - 0.0024 18.0 3.0 0.065 13.3 0.1 2.8 3 0 0 3 3 3 1 Dynamin family AAA_29 PF13555.6 GAK64527.1 - 0.0094 15.7 0.9 3.9 7.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAK64527.1 - 0.019 14.7 0.1 7.9 6.2 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein MpPF26 PF07666.11 GAK64527.1 - 0.047 13.8 0.4 0.24 11.5 0.4 2.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 T2SSE PF00437.20 GAK64527.1 - 0.094 11.8 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0093 PF03653.13 GAK64527.1 - 0.1 12.8 0.9 0.27 11.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) Sre PF03125.18 GAK64527.1 - 0.16 11.1 3.8 0.37 9.9 0.2 2.9 3 1 1 4 4 4 0 C. elegans Sre G protein-coupled chemoreceptor DUF815 PF05673.13 GAK64527.1 - 0.17 11.0 0.6 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CrgA PF06781.12 GAK64527.1 - 1.2 9.2 2.9 3.3 7.8 0.1 2.7 2 0 0 2 2 2 0 Cell division protein CrgA AAA_30 PF13604.6 GAK64527.1 - 2.4 7.8 4.4 18 4.9 0.8 3.0 2 1 0 2 2 2 0 AAA domain Hat1_N PF10394.9 GAK64528.1 - 2e-47 161.4 0.0 3.2e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 GAK64528.1 - 6.2e-06 26.0 0.0 1.3e-05 25.0 0.0 1.4 2 0 0 2 2 2 1 MOZ/SAS family Acetyltransf_1 PF00583.25 GAK64528.1 - 9e-05 22.7 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAK64528.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IMPDH PF00478.25 GAK64529.1 - 9.7e-133 442.4 0.0 2.6e-132 441.0 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 GAK64529.1 - 5.5e-17 62.0 0.0 3e-07 30.8 0.0 2.9 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 GAK64529.1 - 2.6e-10 39.9 1.3 6.3e-10 38.6 1.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 GAK64529.1 - 4e-10 39.6 5.3 5.1e-08 32.7 3.8 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 GAK64529.1 - 4.9e-08 32.7 2.6 2.1e-07 30.7 2.6 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 GAK64529.1 - 0.00084 18.7 2.3 0.00084 18.7 2.3 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 GAK64529.1 - 0.0097 15.3 1.7 0.15 11.5 0.3 2.4 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 GAK64529.1 - 0.012 14.8 0.7 0.13 11.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dus PF01207.17 GAK64529.1 - 0.049 12.7 1.6 0.29 10.2 0.1 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) YpsA PF06908.11 GAK64529.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family EAL PF00563.20 GAK64529.1 - 0.2 11.2 0.3 18 4.7 0.0 2.2 2 0 0 2 2 2 0 EAL domain Aldolase PF01081.19 GAK64529.1 - 0.27 10.6 2.6 0.56 9.6 0.1 2.5 3 0 0 3 3 3 0 KDPG and KHG aldolase DHO_dh PF01180.21 GAK64529.1 - 1.2 8.3 4.4 0.48 9.6 0.6 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase RRP7 PF12923.7 GAK64530.1 - 5.7e-27 94.2 1.5 8.3e-27 93.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 GAK64530.1 - 6e-12 45.7 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 GAK64530.1 - 2.5e-05 24.0 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.6 GAK64530.1 - 0.052 13.9 3.6 0.13 12.7 3.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim17 PF02466.19 GAK64531.1 - 4.9e-34 117.0 6.4 6e-34 116.8 6.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 GAK64531.1 - 1.2 9.2 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF543) AAA PF00004.29 GAK64532.1 - 3.8e-41 140.6 0.0 6.1e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAK64532.1 - 3e-11 43.1 0.0 6.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAK64532.1 - 3.1e-10 39.7 0.2 5.8e-10 38.8 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAK64532.1 - 2.2e-05 24.7 0.0 4.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAK64532.1 - 3.6e-05 23.0 0.0 8.5e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAK64532.1 - 5.6e-05 23.4 0.5 0.02 15.1 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAK64532.1 - 0.00058 19.9 0.3 0.0044 17.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAK64532.1 - 0.0006 20.2 0.3 0.0096 16.3 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 GAK64532.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAK64532.1 - 0.0054 16.9 0.3 0.015 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 GAK64532.1 - 0.0057 17.2 0.1 0.016 15.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 GAK64532.1 - 0.0075 15.6 0.1 0.23 10.8 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.11 GAK64532.1 - 0.0097 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 GAK64532.1 - 0.016 14.8 1.0 0.047 13.3 0.0 2.3 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 GAK64532.1 - 0.022 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAK64532.1 - 0.031 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 GAK64532.1 - 0.052 13.8 0.4 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAK64532.1 - 0.073 12.6 1.1 5.3 6.6 0.3 2.4 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAK64532.1 - 0.086 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 GAK64532.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 GAK64532.1 - 0.11 12.2 0.2 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAK64532.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 GAK64532.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 GAK64532.1 - 0.16 11.1 0.1 0.68 9.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 GAK64532.1 - 0.17 11.8 0.2 0.89 9.5 0.1 2.1 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 GAK64532.1 - 0.19 11.4 0.4 0.48 10.1 0.4 1.7 1 1 0 1 1 1 0 AAA domain Histone PF00125.24 GAK64532.1 - 0.94 9.8 3.7 0.98 9.8 0.1 2.6 3 0 0 3 3 2 0 Core histone H2A/H2B/H3/H4 Nop PF01798.18 GAK64533.1 - 1.1e-85 286.7 0.1 1.1e-85 286.7 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAK64533.1 - 1e-16 61.1 0.4 3.6e-16 59.3 0.4 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF2992 PF11208.8 GAK64533.1 - 1.3 9.2 10.8 4.3 7.6 10.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) EMP24_GP25L PF01105.24 GAK64534.1 - 5.5e-48 163.3 0.0 6.1e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 GAK64534.1 - 0.03 14.6 0.2 0.045 14.0 0.2 1.3 1 0 0 1 1 1 0 SdrD B-like domain Apocytochr_F_C PF01333.19 GAK64534.1 - 0.052 13.6 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Apocytochrome F, C-terminal Ran_BP1 PF00638.18 GAK64535.1 - 3.5e-51 172.6 1.0 5e-51 172.1 1.0 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 GAK64535.1 - 0.00029 20.7 0.9 0.0014 18.6 0.9 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 GAK64535.1 - 0.00094 18.9 0.6 0.0012 18.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) VID27_PH PF17747.1 GAK64535.1 - 0.015 15.5 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 VID27 PH-like domain CK2S PF15011.6 GAK64535.1 - 0.068 13.1 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate Tau95 PF09734.9 GAK64536.1 - 8.5e-35 120.6 0.0 2.7e-34 119.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 GAK64536.1 - 2.2e-20 73.1 0.0 4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain Pol_alpha_B_N PF08418.10 GAK64537.1 - 2.9e-61 207.6 0.0 3.9e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 GAK64537.1 - 4.6e-25 88.2 0.0 6.4e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B BTG PF07742.12 GAK64538.1 - 2e-26 92.1 0.0 3.3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 BTG family VPS13_mid_rpt PF16910.5 GAK64539.1 - 1.9e-90 302.4 0.3 1.9e-90 302.4 0.3 4.8 5 1 1 6 6 6 1 Repeating coiled region of VPS13 VPS13 PF16908.5 GAK64539.1 - 1e-82 277.5 0.5 1.2e-79 267.4 0.0 3.3 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 GAK64539.1 - 3.3e-80 269.3 0.0 2e-77 260.2 0.0 3.1 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 GAK64539.1 - 1.4e-73 246.5 4.0 6.9e-69 231.2 0.2 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 GAK64539.1 - 7.3e-39 132.5 0.2 2.7e-38 130.7 0.2 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAK64539.1 - 5.3e-09 36.3 0.0 8.5e-08 32.5 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Methyltransf_16 PF10294.9 GAK64540.1 - 1.2e-17 64.2 0.0 3.1e-17 62.9 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 GAK64540.1 - 0.085 13.9 0.0 0.14 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4853 PF16145.5 GAK64540.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) Sec8_exocyst PF04048.14 GAK64541.1 - 1.7e-40 138.2 0.4 3.6e-40 137.1 0.4 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 GAK64541.1 - 0.00027 20.3 0.6 0.00047 19.5 0.6 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 GAK64541.1 - 0.012 15.7 2.9 0.02 15.0 0.7 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.9 GAK64541.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Ribosomal_S5_C PF03719.15 GAK64542.1 - 1.1e-18 66.5 0.0 2.7e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GAK64542.1 - 2.6e-16 59.4 1.5 4.3e-16 58.6 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain SPX PF03105.19 GAK64542.1 - 0.51 10.2 5.2 0.71 9.7 5.2 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GAK64542.1 - 1.9 7.2 3.9 2.6 6.8 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRM_1 PF00076.22 GAK64543.1 - 5e-35 119.2 0.0 2.4e-18 65.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR PF05347.15 GAK64545.1 - 0.0052 16.8 2.1 0.0053 16.8 0.4 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DHC PF09626.10 GAK64545.1 - 0.083 13.8 0.3 11 7.0 0.1 2.3 2 0 0 2 2 2 0 Dihaem cytochrome c Cnn_1N PF07989.11 GAK64545.1 - 1.2 9.3 5.9 3.8 7.7 1.9 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Rx_N PF18052.1 GAK64545.1 - 2.5 8.5 5.8 7.4 6.9 2.2 2.3 2 0 0 2 2 2 0 Rx N-terminal domain zf-C2H2 PF00096.26 GAK64546.1 - 0.0022 18.4 18.0 0.095 13.2 4.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK64546.1 - 0.034 15.0 2.8 0.034 15.0 2.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAK64546.1 - 0.045 14.0 8.3 0.12 12.7 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAK64546.1 - 0.61 10.2 10.1 0.045 13.8 1.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PX PF00787.24 GAK64547.1 - 4.3e-17 62.1 0.2 1.7e-16 60.2 0.2 2.0 1 1 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 GAK64547.1 - 3.1e-08 33.4 0.0 7.2e-07 28.9 0.1 2.7 2 1 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 GAK64547.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Glyco_hydro_43 PF04616.14 GAK64548.1 - 9.2e-08 31.7 0.5 3.7e-07 29.7 0.3 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 DUF5348 PF17295.2 GAK64548.1 - 0.02 14.8 0.9 0.19 11.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5348) Sec62 PF03839.16 GAK64549.1 - 2.1e-51 174.5 2.3 5.2e-51 173.2 2.3 1.6 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 GAK64549.1 - 0.85 8.7 6.9 1.2 8.2 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Cnd1 PF12717.7 GAK64550.1 - 1.8e-57 193.9 1.2 3.4e-50 170.2 0.0 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 GAK64550.1 - 4.7e-44 150.2 0.0 4.7e-44 150.2 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 GAK64550.1 - 4.4e-09 35.8 4.3 3 8.3 0.0 7.9 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 GAK64550.1 - 1.1e-07 32.2 1.5 0.056 13.8 0.0 5.6 4 1 1 5 5 4 2 HEAT repeats Adaptin_N PF01602.20 GAK64550.1 - 1.2e-06 27.4 1.7 0.0022 16.6 0.6 3.6 3 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 GAK64550.1 - 7.8e-05 22.0 2.2 0.00043 19.6 0.2 2.8 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Mpp10 PF04006.12 GAK64550.1 - 0.0018 16.8 9.2 0.0018 16.8 9.2 1.6 2 0 0 2 2 1 1 Mpp10 protein CDC45 PF02724.14 GAK64550.1 - 0.0023 16.3 12.0 0.0038 15.6 12.0 1.2 1 0 0 1 1 1 1 CDC45-like protein RTP1_C1 PF10363.9 GAK64550.1 - 0.0027 17.9 0.1 6.4 7.0 0.0 4.0 2 2 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Tub_N PF16322.5 GAK64550.1 - 0.015 15.7 6.9 0.055 13.9 6.9 2.0 1 0 0 1 1 1 0 Tubby N-terminal Cohesin_HEAT PF12765.7 GAK64550.1 - 0.037 14.3 0.0 4.8 7.6 0.0 4.1 4 0 0 4 4 3 0 HEAT repeat associated with sister chromatid cohesion PBP_like PF12727.7 GAK64550.1 - 0.053 12.6 1.5 0.14 11.3 1.5 1.7 1 0 0 1 1 1 0 PBP superfamily domain DUF913 PF06025.12 GAK64550.1 - 0.11 11.5 3.4 0.074 12.0 1.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 GAK64550.1 - 0.23 9.5 26.5 14 3.6 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase phi Sigma70_ner PF04546.13 GAK64550.1 - 0.33 10.8 20.1 0.028 14.3 13.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 GAK64550.1 - 1 8.7 26.3 0.12 11.7 20.2 2.3 2 0 0 2 2 2 0 SDA1 Apt1 PF10351.9 GAK64550.1 - 1.2 7.9 5.0 0.74 8.6 2.3 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Merozoite_SPAM PF07133.11 GAK64550.1 - 1.6 8.7 22.0 4.6 7.2 22.0 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HEAT_EZ PF13513.6 GAK64550.1 - 2.2 8.9 16.1 0.21 12.1 0.3 5.7 6 1 1 7 7 4 0 HEAT-like repeat RRN3 PF05327.11 GAK64550.1 - 7.8 4.9 17.0 18 3.7 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIF_alpha PF05793.12 GAK64550.1 - 8.1 4.9 23.6 20 3.6 23.6 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.15 GAK64550.1 - 9.3 4.9 7.7 3.2 6.4 4.8 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TPR_14 PF13428.6 GAK64551.1 - 0.19 12.6 8.1 8.1 7.6 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat CwfJ_C_1 PF04677.15 GAK64552.1 - 1.3e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 GAK64552.1 - 2.4e-10 40.0 2.4 4.2e-10 39.2 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAK64552.1 - 0.00062 19.7 0.3 0.0013 18.7 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle CwfJ_C_2 PF04676.14 GAK64552.1 - 0.0039 18.0 0.0 0.008 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 VMA21 PF09446.10 GAK64553.1 - 2.7e-11 43.4 10.2 4.5e-11 42.7 10.2 1.3 1 1 0 1 1 1 1 VMA21-like domain DUF4199 PF13858.6 GAK64553.1 - 0.36 11.2 2.9 0.43 11.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ORC2 PF04084.14 GAK64554.1 - 9.6e-75 251.5 0.0 1.3e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Serglycin PF04360.12 GAK64554.1 - 0.055 13.4 2.1 0.14 12.1 1.3 2.0 2 0 0 2 2 2 0 Serglycin AF-4 PF05110.13 GAK64554.1 - 3.3 5.7 14.7 0.034 12.3 5.5 1.9 2 0 0 2 2 2 0 AF-4 proto-oncoprotein PIN_4 PF13638.6 GAK64555.1 - 1.2e-23 83.8 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain DUF1572 PF07609.11 GAK64561.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) DLH PF01738.18 GAK64563.1 - 1.7e-23 83.3 0.1 2.7e-23 82.7 0.1 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAK64563.1 - 0.023 14.4 0.0 0.97 9.0 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Phosphodiest PF01663.22 GAK64564.1 - 3.5e-74 250.5 0.9 4.2e-74 250.3 0.9 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SHNi-TPR PF10516.9 GAK64565.1 - 4.2e-11 42.1 0.3 1.1e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 GAK64565.1 - 0.0032 17.7 10.5 0.074 13.3 1.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat MSP1_C PF07462.11 GAK64565.1 - 0.041 12.6 0.9 0.07 11.8 0.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TPR_2 PF07719.17 GAK64565.1 - 0.094 12.9 6.1 4 7.8 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CHASE3 PF05227.13 GAK64565.1 - 2.5 8.0 13.2 1.3 8.9 0.8 3.4 2 1 1 3 3 3 0 CHASE3 domain TPR_1 PF00515.28 GAK64567.1 - 2.4e-23 80.9 2.1 6.5e-08 32.1 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAK64567.1 - 9.1e-22 75.4 11.1 2.7e-06 27.1 0.1 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAK64567.1 - 4.9e-16 57.5 2.8 0.0017 18.4 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAK64567.1 - 6.4e-15 54.5 5.2 0.00041 20.0 0.1 4.3 2 1 2 4 4 4 3 TPR repeat TPR_14 PF13428.6 GAK64567.1 - 3.6e-13 49.1 12.8 0.00072 20.2 0.1 6.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAK64567.1 - 7.3e-11 42.4 10.3 0.0031 18.0 0.2 4.3 3 2 1 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAK64567.1 - 1.9e-10 41.2 15.1 3.5e-06 27.5 0.1 5.7 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAK64567.1 - 5.4e-10 39.4 9.7 0.036 14.4 3.5 5.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAK64567.1 - 3.5e-09 36.4 4.9 0.0025 18.1 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64567.1 - 5.4e-05 23.3 2.9 0.0085 16.3 0.7 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAK64567.1 - 6.9e-05 23.2 10.0 2.7 8.8 0.2 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAK64567.1 - 0.0016 18.8 9.7 0.11 12.8 0.3 4.8 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK64567.1 - 0.0018 18.4 4.2 0.53 10.5 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAK64567.1 - 0.003 17.5 7.9 0.45 10.7 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat LAL_C2 PF18603.1 GAK64567.1 - 0.048 13.8 0.6 6.3 7.0 0.0 3.3 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 Wzy_C_2 PF11846.8 GAK64567.1 - 0.051 13.5 3.7 5.2 6.9 0.0 3.3 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 GAK64567.1 - 0.13 12.7 12.8 0.44 11.0 2.7 3.9 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Coatomer_E PF04733.14 GAK64567.1 - 0.18 11.2 1.5 4.3 6.7 0.1 2.8 3 1 0 3 3 3 0 Coatomer epsilon subunit TPR_10 PF13374.6 GAK64567.1 - 1.6 8.7 14.4 0.58 10.1 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_28 PF03033.20 GAK64568.1 - 7.7e-22 77.8 0.0 1.4e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 GAK64568.1 - 2.8e-05 24.0 0.0 0.0052 16.7 0.0 2.7 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.18 GAK64568.1 - 0.0077 15.1 0.0 0.016 14.1 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase RNase_P_Rpp14 PF01900.19 GAK64569.1 - 1.7e-23 82.8 0.0 2.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family IBR PF01485.21 GAK64570.1 - 2.8e-19 69.1 39.0 1.7e-12 47.4 4.4 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 GAK64570.1 - 1.6e-08 34.8 4.6 1.4e-07 31.8 4.6 2.3 1 1 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 GAK64570.1 - 2.4e-05 24.6 4.4 2.4e-05 24.6 4.4 4.8 3 1 1 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 GAK64570.1 - 0.00012 21.7 4.7 0.00035 20.3 4.7 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAK64570.1 - 0.00013 21.9 4.6 0.00013 21.9 4.6 3.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAK64570.1 - 0.0004 20.2 6.5 0.0004 20.2 6.5 4.5 3 1 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK64570.1 - 0.0031 17.4 7.6 0.0031 17.4 7.6 4.1 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAK64570.1 - 0.0048 16.7 4.5 0.0048 16.7 4.5 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF3025 PF11227.8 GAK64570.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Prok-RING_4 PF14447.6 GAK64570.1 - 1.4 8.8 33.6 0.42 10.5 5.1 4.3 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 Nup192 PF11894.8 GAK64572.1 - 0 1216.7 0.0 0 1216.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Glyco_hydro_45 PF02015.16 GAK64573.1 - 9.7e-64 215.1 10.6 1.3e-63 214.8 10.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF1096 PF06493.11 GAK64573.1 - 1.7 9.1 10.2 1.5 9.3 4.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1096) DUF3150 PF11348.8 GAK64575.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Abhydrolase_3 PF07859.13 GAK64577.1 - 6.6e-36 124.1 0.2 1.4e-35 123.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 GAK64577.1 - 5.7e-07 28.8 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAK64577.1 - 0.04 12.8 0.0 8 5.2 0.0 2.9 3 0 0 3 3 3 0 Steryl acetyl hydrolase GCP_C_terminal PF04130.13 GAK64578.1 - 3.2e-21 76.1 0.0 8.9e-12 45.1 0.0 2.6 2 1 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAK64578.1 - 3.6e-20 72.8 0.0 6.3e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Alg6_Alg8 PF03155.15 GAK64579.1 - 9.4e-120 400.8 16.9 1.4e-93 314.5 7.3 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 GAK64579.1 - 7.6 5.9 11.3 8.5 5.7 2.9 2.9 2 1 0 3 3 3 0 ALG3 protein Ribosomal_L37ae PF01780.19 GAK64580.1 - 2.5e-41 139.6 8.6 3.7e-41 139.1 8.6 1.3 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 GAK64580.1 - 0.0034 17.5 1.1 0.0053 16.9 1.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-BED PF02892.15 GAK64580.1 - 0.037 14.0 3.0 2.2 8.4 0.1 2.4 1 1 1 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 GAK64580.1 - 0.08 12.9 3.1 0.14 12.2 3.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 GAK64580.1 - 4.3 7.9 6.4 6.6 7.4 1.3 2.5 1 1 1 2 2 2 0 Zinc-finger double domain Amidase PF01425.21 GAK64581.1 - 9.9e-71 239.0 2.0 3.9e-68 230.5 1.7 2.1 2 0 0 2 2 2 2 Amidase G-alpha PF00503.20 GAK64582.1 - 3.1e-109 365.4 0.5 3.5e-109 365.2 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAK64582.1 - 5.6e-13 48.7 0.1 5.9e-08 32.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 GAK64582.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 GAK64582.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 GAK64582.1 - 0.048 13.0 1.1 6.6 6.0 0.0 2.4 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Roc PF08477.13 GAK64582.1 - 0.049 13.9 0.0 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2985 PF11204.8 GAK64582.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) MRP-L47 PF06984.13 GAK64583.1 - 2e-15 56.6 2.9 8.6e-15 54.6 2.7 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 GAK64583.1 - 0.0013 18.6 1.2 0.0034 17.3 1.2 1.8 1 1 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S24e PF01282.19 GAK64584.1 - 4.8e-32 109.8 0.0 9.1e-32 108.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 GAK64584.1 - 0.0097 15.8 1.0 0.0097 15.8 1.0 1.5 2 0 0 2 2 2 1 RRXRR protein HVSL PF09749.9 GAK64585.1 - 6.2e-29 101.2 0.0 7.4e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 GAK64585.1 - 0.00019 21.3 0.1 0.00046 20.1 0.1 1.7 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily Pkinase PF00069.25 GAK64586.1 - 1.7e-51 175.1 0.0 8.7e-51 172.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64586.1 - 5.3e-25 88.2 0.0 1.1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PFK PF00365.20 GAK64587.1 - 1.5e-185 615.1 0.5 4.3e-88 295.3 0.2 3.2 3 0 0 3 3 3 3 Phosphofructokinase PapJ PF14855.6 GAK64587.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Cyclase PF04199.13 GAK64588.1 - 1.2e-14 54.7 0.2 4.7e-14 52.8 0.1 1.8 1 1 1 2 2 2 1 Putative cyclase RSN1_7TM PF02714.15 GAK64589.1 - 1.9e-73 247.1 17.2 1.9e-73 247.1 17.2 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAK64589.1 - 5.2e-41 140.8 0.3 7.6e-41 140.3 0.3 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAK64589.1 - 5.6e-37 126.9 4.1 5.6e-37 126.9 4.1 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 GAK64589.1 - 2.6e-09 37.1 0.0 6.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Glyco_hydro_28 PF00295.17 GAK64590.1 - 1.7e-120 402.0 19.6 1.9e-120 401.8 19.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TRAM_LAG1_CLN8 PF03798.16 GAK64592.1 - 8.1e-07 29.0 11.8 9.1e-07 28.8 11.0 1.5 1 1 0 1 1 1 1 TLC domain Aldedh PF00171.22 GAK64593.1 - 8.3e-180 598.2 0.2 9.4e-180 598.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAK64593.1 - 0.0003 20.3 0.0 0.0022 17.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.14 GAK64593.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) GFA PF04828.14 GAK64595.1 - 9.2e-21 74.0 3.7 1.3e-20 73.5 3.7 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 GAK64595.1 - 0.15 12.3 1.7 0.36 11.2 0.1 2.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain COG7 PF10191.9 GAK64596.1 - 0.02 13.1 0.0 0.028 12.7 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Nab2p_Zf1 PF18260.1 GAK64596.1 - 0.4 10.6 3.7 0.73 9.8 3.7 1.3 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 FAA_hydrolase PF01557.18 GAK64597.1 - 4.2e-66 222.7 0.0 6.7e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 GAK64597.1 - 6.8e-27 94.7 0.6 4.7e-23 82.2 0.6 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK64597.1 - 6e-20 72.8 1.8 9.4e-20 72.2 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK64597.1 - 3.2e-18 65.9 0.3 7e-18 64.8 0.3 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAK64597.1 - 2.7e-05 23.0 0.0 4.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 GAK64597.1 - 3.5e-05 23.7 0.6 0.00075 19.4 0.3 2.2 1 1 1 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 GAK64597.1 - 0.0018 18.4 0.0 0.0061 16.6 0.0 1.9 1 1 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 GAK64597.1 - 0.0043 16.8 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family KH_2 PF07650.17 GAK64597.1 - 0.034 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 KH domain Esterase PF00756.20 GAK64597.1 - 0.047 13.3 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 GAK64597.1 - 0.24 11.1 1.5 0.59 9.8 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein Gpr1_Fun34_YaaH PF01184.19 GAK64598.1 - 1.7e-69 233.6 19.9 2e-69 233.3 19.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family B12D PF06522.11 GAK64598.1 - 3.7 7.4 4.6 0.83 9.5 0.2 2.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Yip1 PF04893.17 GAK64598.1 - 7.1 6.3 26.7 15 5.2 26.7 1.6 1 1 0 1 1 1 0 Yip1 domain Sugar_tr PF00083.24 GAK64599.1 - 1.3e-107 360.5 25.9 1.5e-107 360.3 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK64599.1 - 5.5e-18 65.0 44.0 3.2e-16 59.2 14.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CAP59_mtransfer PF11735.8 GAK64600.1 - 7.5e-70 235.3 0.0 9.9e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF2070 PF09843.9 GAK64600.1 - 0.23 9.7 2.8 0.3 9.3 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 GAK64601.1 - 2.7e-26 92.4 32.0 2.7e-26 92.4 32.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sulf_transp PF04143.14 GAK64602.1 - 1.6e-09 37.8 23.0 4.2e-07 29.8 12.1 3.2 3 1 0 3 3 3 2 Sulphur transport HLH PF00010.26 GAK64603.1 - 4e-05 23.5 0.0 7.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC24 PF15669.5 GAK64603.1 - 0.036 13.9 2.2 0.074 12.9 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family TFR_dimer PF04253.15 GAK64603.1 - 0.081 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Sugar_tr PF00083.24 GAK64604.1 - 1.7e-87 294.2 22.0 2e-87 294.0 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK64604.1 - 1.8e-15 56.7 45.5 9.7e-12 44.5 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4637 PF15470.6 GAK64605.1 - 0.0077 16.0 0.2 0.0096 15.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) TAL_FSA PF00923.19 GAK64606.1 - 8e-33 114.0 0.0 1.2e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase His_Phos_2 PF00328.22 GAK64607.1 - 8.3e-37 127.4 0.0 1e-36 127.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.23 GAK64608.1 - 0.00026 20.6 0.3 0.00042 19.9 0.3 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rad1 PF02144.16 GAK64609.1 - 6e-98 327.3 0.0 7.3e-98 327.0 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CD4-extracel PF09191.10 GAK64609.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 CD4, extracellular DUF2236 PF09995.9 GAK64610.1 - 3.2e-50 171.4 1.0 3.2e-50 171.4 1.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) BP28CT PF08146.12 GAK64612.1 - 1.8e-38 131.9 0.0 1.1e-35 122.8 0.1 3.5 2 0 0 2 2 2 2 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 GAK64612.1 - 5.2e-15 55.8 3.7 5.2e-15 55.8 3.7 5.4 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 GAK64612.1 - 0.00049 20.5 17.4 0.99 10.0 0.0 8.4 7 0 0 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 GAK64612.1 - 0.013 15.5 0.3 1.7 8.6 0.0 3.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 GAK64612.1 - 0.025 14.1 0.0 1 8.8 0.0 3.3 3 0 0 3 3 3 0 Tti2 family HEAT PF02985.22 GAK64612.1 - 1.5 9.3 18.5 0.052 13.8 1.1 5.8 5 0 0 5 5 5 0 HEAT repeat RTP1_C1 PF10363.9 GAK64612.1 - 3.3 7.9 6.3 8.7 6.6 0.1 4.3 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DASH_Spc19 PF08287.11 GAK64615.1 - 3.5e-35 121.2 8.3 8e-35 120.1 7.8 1.7 1 1 0 1 1 1 1 Spc19 SlyX PF04102.12 GAK64615.1 - 0.011 16.3 7.5 1.9 9.2 2.0 3.2 2 1 1 3 3 3 0 SlyX BRE1 PF08647.11 GAK64615.1 - 0.015 15.3 2.2 0.015 15.3 2.2 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Wtap PF17098.5 GAK64615.1 - 0.027 14.4 2.9 0.13 12.1 2.4 2.0 2 0 0 2 2 2 0 WTAP/Mum2p family FUSC PF04632.12 GAK64615.1 - 0.03 12.9 6.3 0.03 12.9 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.6 GAK64615.1 - 0.046 12.4 0.3 0.071 11.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 GAK64615.1 - 0.089 13.0 2.7 0.094 12.9 1.2 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family tRNA-synt_His PF13393.6 GAK64615.1 - 0.09 12.0 2.0 0.11 11.7 2.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Topo-VIb_trans PF09239.11 GAK64615.1 - 0.095 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer DivIC PF04977.15 GAK64615.1 - 0.94 9.3 7.8 2.3 8.0 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator COG5 PF10392.9 GAK64615.1 - 1.1 9.4 5.9 0.62 10.2 3.3 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 GAK64615.1 - 1.3 8.3 6.2 1.7 8.0 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSNAXIP1_N PF15739.5 GAK64615.1 - 1.3 9.4 4.6 1.1 9.7 1.5 2.2 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus ATP_sub_h PF10775.9 GAK64615.1 - 3.4 7.7 8.1 2 8.5 0.4 2.6 2 1 0 2 2 2 0 ATP synthase complex subunit h Spc24 PF08286.11 GAK64615.1 - 3.5 7.9 5.2 63 3.9 5.2 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 GAK64615.1 - 4 7.9 9.5 17 6.0 1.2 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) VASt PF16016.5 GAK64616.1 - 1.3e-37 129.6 0.0 2.4e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAK64616.1 - 3.2e-24 85.0 0.0 5.6e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Wbp11 PF09429.10 GAK64617.1 - 2.4e-13 50.3 16.5 2.4e-13 50.3 16.5 2.9 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.7 GAK64617.1 - 1.2e-12 48.3 14.4 1.2e-12 48.3 14.4 3.3 2 2 0 2 2 2 1 mRNA biogenesis factor Peptidase_C48 PF02902.19 GAK64617.1 - 1.1e-10 41.8 0.2 2.8e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF3450 PF11932.8 GAK64617.1 - 0.014 14.7 12.4 0.024 13.9 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 GAK64617.1 - 0.13 12.5 0.8 0.31 11.3 0.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 GAK64617.1 - 0.3 9.9 7.6 0.48 9.3 7.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fungal_trans_2 PF11951.8 GAK64617.1 - 0.76 8.5 5.2 1.7 7.4 5.2 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain TMPIT PF07851.13 GAK64617.1 - 5 6.3 5.9 7.5 5.7 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein INCENP_ARK-bind PF03941.15 GAK64619.1 - 4.2e-12 45.8 0.2 4.2e-12 45.8 0.2 4.1 4 0 0 4 4 4 1 Inner centromere protein, ARK binding region Acyltransferase PF01553.21 GAK64621.1 - 1.2e-11 44.4 0.0 3e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase TTL PF03133.15 GAK64622.1 - 9.1e-46 156.3 0.0 2e-45 155.2 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family CENP-B_dimeris PF09026.10 GAK64622.1 - 0.00062 20.1 5.1 0.0016 18.8 5.1 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nro1 PF12753.7 GAK64622.1 - 0.12 11.3 6.3 0.2 10.6 6.3 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DNA_pol_phi PF04931.13 GAK64622.1 - 1.8 6.5 5.6 2.6 6.0 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Dicty_REP PF05086.12 GAK64622.1 - 3 5.7 7.2 4.3 5.2 7.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cwf_Cwc_15 PF04889.12 GAK64622.1 - 6.5 6.4 7.4 11 5.7 7.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAK64622.1 - 7.6 5.8 7.4 12 5.1 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_5 PF13857.6 GAK64624.1 - 1e-08 35.3 0.2 0.00029 21.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK64624.1 - 6.7e-07 29.8 0.0 2.1e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK64624.1 - 8.7e-07 29.4 1.1 0.0041 17.7 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAK64624.1 - 2.4e-06 27.7 0.1 0.061 13.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAK64624.1 - 1.8e-05 24.7 0.6 0.16 12.6 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeat Nrap_D4 PF17405.2 GAK64625.1 - 3e-58 196.7 0.0 5.6e-58 195.8 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 GAK64625.1 - 2e-51 173.8 0.0 1.8e-50 170.6 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 GAK64625.1 - 2.4e-44 151.0 0.0 5e-43 146.7 0.0 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 GAK64625.1 - 8.4e-44 149.3 0.1 1.3e-43 148.6 0.1 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 GAK64625.1 - 1.9e-42 145.0 0.0 3.7e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 GAK64625.1 - 7.7e-32 110.3 0.0 2e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 PI31_Prot_N PF11566.8 GAK64626.1 - 3.7e-49 166.7 0.0 4.7e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 GAK64626.1 - 3.5e-12 47.3 18.5 3.5e-12 47.3 18.5 3.7 3 1 0 3 3 3 1 PI31 proteasome regulator Adaptin_N PF01602.20 GAK64627.1 - 4.8e-100 335.6 7.0 7.8e-100 334.9 7.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 GAK64627.1 - 1.6e-59 199.4 0.0 4.8e-59 197.9 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 GAK64627.1 - 5e-58 195.0 0.1 5e-58 195.0 0.1 2.3 3 0 0 3 3 3 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 GAK64627.1 - 2.3e-09 37.5 5.4 0.027 14.9 0.0 5.0 3 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAK64627.1 - 2.6e-09 37.3 12.3 2.2e-07 31.0 0.0 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAK64627.1 - 1.9e-07 30.7 0.2 0.02 15.1 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat DUF5578 PF17741.1 GAK64627.1 - 0.0015 18.0 4.5 0.09 12.2 1.8 2.7 1 1 0 2 2 2 2 Family of unknown function (DUF5578) ParcG PF10274.9 GAK64627.1 - 0.016 15.3 2.9 0.57 10.3 0.1 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein DUF5071 PF16804.5 GAK64627.1 - 0.022 15.0 1.1 0.29 11.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5071) DUF3810 PF12725.7 GAK64627.1 - 0.026 13.9 0.1 0.067 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Arm PF00514.23 GAK64627.1 - 0.075 13.1 3.3 42 4.4 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF1664 PF07889.12 GAK64627.1 - 0.67 10.0 2.7 6.4 6.8 0.7 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) MutS_V PF00488.21 GAK64628.1 - 2.4e-65 220.1 0.4 4.3e-65 219.3 0.4 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 GAK64628.1 - 7.6e-34 116.4 0.0 3.4e-33 114.2 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 GAK64628.1 - 1e-33 117.2 0.3 4.8e-33 115.0 0.0 2.3 2 0 0 2 2 2 1 MutS domain III Sec63 PF02889.16 GAK64628.1 - 1.7e-24 86.4 0.0 2.8e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 GAK64628.1 - 1.7e-22 80.0 0.0 3.9e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Acetyltransf_13 PF13880.6 GAK64628.1 - 2.8e-16 59.2 0.1 1.6e-15 56.8 0.0 2.3 3 0 0 3 3 2 1 ESCO1/2 acetyl-transferase Helicase_C PF00271.31 GAK64628.1 - 8.2e-12 45.5 0.0 2.4e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2_3 PF13878.6 GAK64628.1 - 3.1e-11 42.9 1.8 7.2e-11 41.7 1.8 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO ResIII PF04851.15 GAK64628.1 - 2.6e-10 40.5 0.0 4.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MutS_II PF05188.17 GAK64628.1 - 4e-10 40.1 0.0 1.3e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAK64628.1 - 2.5e-06 27.7 0.0 5.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_19 PF13245.6 GAK64628.1 - 0.0016 18.8 0.1 0.34 11.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain HHH_5 PF14520.6 GAK64628.1 - 0.041 14.5 0.0 0.98 10.1 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain AAA_25 PF13481.6 GAK64628.1 - 0.068 12.7 1.2 0.48 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 GAK64629.1 - 6.5e-45 153.6 0.0 2.4e-44 151.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64629.1 - 1.4e-26 93.4 0.0 1.3e-25 90.2 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 GAK64629.1 - 0.019 14.4 0.2 0.034 13.5 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAK64629.1 - 0.065 12.5 0.2 0.93 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Herpes_ICP4_N PF03584.15 GAK64629.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Enolase_C PF00113.22 GAK64630.1 - 1.8e-140 467.3 0.1 2.5e-140 466.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAK64630.1 - 3.5e-58 195.4 0.0 5.7e-58 194.8 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAK64630.1 - 6.5e-08 32.4 0.0 9.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAK64630.1 - 0.033 13.3 0.4 0.1 11.7 0.1 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus EMP24_GP25L PF01105.24 GAK64631.1 - 6.2e-40 137.1 0.1 7.2e-40 136.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 GAK64631.1 - 0.028 14.0 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Trimerisation motif Josephin PF02099.17 GAK64632.1 - 7.5e-47 159.5 0.7 1.7e-46 158.3 0.1 2.0 2 0 0 2 2 2 1 Josephin UIM PF02809.20 GAK64632.1 - 4e-05 23.3 24.8 0.064 13.2 1.6 4.6 4 0 0 4 4 4 3 Ubiquitin interaction motif ATG27 PF09451.10 GAK64633.1 - 1.2e-76 258.1 0.0 2.5e-76 257.0 0.0 1.5 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 GAK64633.1 - 0.19 11.8 0.0 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat ABC_tran PF00005.27 GAK64634.1 - 9.7e-34 116.8 0.1 3.1e-16 60.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 GAK64634.1 - 7.2e-14 51.3 5.8 7.2e-14 51.3 5.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 GAK64634.1 - 4.1e-11 42.7 5.0 0.0002 20.9 0.5 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAK64634.1 - 1.1e-08 35.3 4.3 0.26 11.1 1.1 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 GAK64634.1 - 1.4e-05 25.6 0.0 0.03 14.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GAK64634.1 - 1.5e-05 24.9 0.1 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAK64634.1 - 1.8e-05 25.1 0.0 0.0058 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAK64634.1 - 2.4e-05 24.2 3.9 0.1 12.3 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 GAK64634.1 - 4.3e-05 24.0 0.1 0.023 15.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Fer4 PF00037.27 GAK64634.1 - 5.6e-05 22.8 2.9 5.6e-05 22.8 2.9 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_10 PF13237.6 GAK64634.1 - 0.00013 22.0 8.8 0.0052 16.9 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_29 PF13555.6 GAK64634.1 - 0.00016 21.3 0.5 0.51 10.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 GAK64634.1 - 0.00048 20.5 0.3 0.2 12.1 0.0 3.1 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.12 GAK64634.1 - 0.00069 19.6 1.2 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_6 PF12837.7 GAK64634.1 - 0.0007 19.6 11.3 0.0041 17.1 2.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_7 PF12775.7 GAK64634.1 - 0.00081 19.0 0.3 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 GAK64634.1 - 0.0014 18.3 0.4 0.47 10.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAK64634.1 - 0.0015 17.8 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 GAK64634.1 - 0.0025 18.0 0.8 0.5 10.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 GAK64634.1 - 0.0025 17.7 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_21 PF14697.6 GAK64634.1 - 0.0034 17.5 10.9 0.0077 16.3 10.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 GAK64634.1 - 0.0043 17.0 0.2 0.086 12.9 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_7 PF12838.7 GAK64634.1 - 0.0047 17.5 8.1 0.011 16.3 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.22 GAK64634.1 - 0.0059 16.2 2.7 0.27 10.8 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 GAK64634.1 - 0.0078 16.5 0.9 1.7 8.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 GAK64634.1 - 0.016 15.4 9.9 0.048 13.8 10.0 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_18 PF13238.6 GAK64634.1 - 0.024 15.2 0.6 8.1 7.0 0.1 2.9 2 1 1 3 3 3 0 AAA domain VirE PF05272.11 GAK64634.1 - 0.028 14.2 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E SbcCD_C PF13558.6 GAK64634.1 - 0.036 14.3 0.0 12 6.2 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 GAK64634.1 - 0.042 13.6 0.4 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 GAK64634.1 - 0.058 14.3 0.3 0.058 14.3 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 GAK64634.1 - 0.06 13.4 0.7 9.8 6.3 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 GAK64634.1 - 0.071 12.8 0.8 5.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase AAA_14 PF13173.6 GAK64634.1 - 0.087 12.9 1.3 22 5.1 0.0 3.4 2 1 0 3 3 3 0 AAA domain MeaB PF03308.16 GAK64634.1 - 0.2 10.6 0.2 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 GAK64634.1 - 0.23 11.5 1.4 3.1 7.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 GAK64634.1 - 0.26 11.5 0.4 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 GAK64634.1 - 0.27 11.1 1.3 7.7 6.4 0.1 3.1 3 0 0 3 3 3 0 NTPase Fer4_8 PF13183.6 GAK64634.1 - 0.33 11.4 0.1 0.33 11.4 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_23 PF13476.6 GAK64634.1 - 0.66 10.4 11.5 0.1 13.1 1.0 2.7 2 1 1 3 3 3 0 AAA domain Fer4_2 PF12797.7 GAK64634.1 - 2 8.7 9.7 0.29 11.3 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SAM_2 PF07647.17 GAK64637.1 - 2.1e-10 40.6 0.0 5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAK64637.1 - 1.6e-05 25.3 0.2 4.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) IGR PF09597.10 GAK64637.1 - 0.066 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif DUF2201 PF09967.9 GAK64637.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Mcp5_PH PF12814.7 GAK64638.1 - 1.9e-45 153.9 0.1 4.8e-45 152.6 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 GAK64638.1 - 9.2e-06 26.1 0.0 2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PH domain BRE1 PF08647.11 GAK64638.1 - 7.6e-05 22.7 13.6 7.6e-05 22.7 13.6 12.0 6 4 6 13 13 13 4 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 GAK64638.1 - 0.0013 19.2 24.2 0.0013 19.2 24.2 10.5 4 2 7 12 12 12 5 Fez1 TMF_TATA_bd PF12325.8 GAK64638.1 - 0.0061 16.8 13.8 0.0061 16.8 13.8 13.4 3 3 10 14 14 14 3 TATA element modulatory factor 1 TATA binding DcpS_C PF11969.8 GAK64638.1 - 0.015 15.8 8.8 1.5 9.4 0.4 4.1 3 0 0 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding HSF_DNA-bind PF00447.17 GAK64639.1 - 4e-31 107.5 0.6 7.6e-31 106.6 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 GAK64639.1 - 4.8e-25 87.9 0.1 3.4e-24 85.1 0.0 2.4 3 0 0 3 3 3 1 Response regulator receiver domain GCFC PF07842.12 GAK64640.1 - 1.2e-64 218.6 1.3 1.8e-64 218.0 1.3 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 GAK64640.1 - 7.3e-12 45.6 3.8 7.3e-12 45.6 3.8 3.5 3 1 1 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.23 GAK64640.1 - 4.7e-10 39.2 2.0 6.1e-10 38.8 0.4 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 GAK64640.1 - 4.7e-05 23.4 3.5 0.0066 16.5 0.1 2.8 2 0 0 2 2 2 2 G-patch domain zf-rbx1 PF12678.7 GAK64641.1 - 2.1e-10 40.7 1.5 2.2e-09 37.4 0.5 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAK64641.1 - 4.9e-10 39.6 5.6 1.2e-08 35.1 2.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAK64641.1 - 1e-08 34.9 6.0 3.8e-08 33.1 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAK64641.1 - 3.4e-07 29.9 1.0 0.0016 18.1 0.2 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 GAK64641.1 - 8.3e-06 25.6 2.5 3.7e-05 23.5 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAK64641.1 - 0.00033 20.2 0.8 0.00095 18.7 0.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAK64641.1 - 0.00064 19.7 1.9 0.0009 19.3 0.8 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAK64641.1 - 0.00071 19.5 2.1 0.0011 18.9 0.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAK64641.1 - 0.001 18.9 4.5 0.0014 18.5 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK64641.1 - 0.0049 16.7 1.0 0.0049 16.7 1.0 2.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAK64641.1 - 0.008 16.2 1.7 0.015 15.3 0.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger FAP PF07174.11 GAK64641.1 - 0.069 12.6 11.2 0.49 9.8 10.4 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) zf-RING_4 PF14570.6 GAK64641.1 - 0.21 11.4 2.7 0.15 11.9 0.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GAK64641.1 - 0.51 10.6 3.0 1 9.6 0.8 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 GAK64641.1 - 0.55 10.6 3.0 1.1 9.6 3.0 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 GAK64641.1 - 1 9.5 6.2 0.15 12.2 1.7 1.9 2 0 0 2 2 2 0 RING-variant domain DEC-1_N PF04625.13 GAK64641.1 - 3.7 6.5 9.2 5.9 5.8 9.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region UPF0565 PF10561.9 GAK64642.1 - 0.095 11.9 0.9 0.11 11.7 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Asp-B-Hydro_N PF05279.11 GAK64642.1 - 0.43 10.6 12.5 0.55 10.2 12.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PA26 PF04636.13 GAK64642.1 - 1.6 7.6 8.3 2 7.2 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 GAK64642.1 - 9.9 5.9 18.9 14 5.4 18.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FHA PF00498.26 GAK64643.1 - 7.2e-13 48.7 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 GAK64643.1 - 5.3e-11 42.1 12.4 8.7e-11 41.4 12.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAK64643.1 - 1.1e-06 28.8 13.2 1.8e-06 28.2 13.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAK64643.1 - 0.0035 17.1 13.7 0.0057 16.5 13.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAK64643.1 - 0.0076 16.5 8.4 0.015 15.6 8.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAK64643.1 - 0.0097 15.8 12.7 0.015 15.1 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAK64643.1 - 0.016 15.3 5.0 0.028 14.5 5.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAK64643.1 - 0.056 13.4 11.5 0.095 12.7 11.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK64643.1 - 1.7 8.8 12.4 3.1 7.9 12.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 GAK64643.1 - 3.7 7.5 8.1 6.9 6.6 8.1 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 GAK64643.1 - 7.3 6.5 11.3 13 5.8 11.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GAK64643.1 - 8.9 6.0 9.8 16 5.2 9.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ATG11 PF10377.9 GAK64644.1 - 1.6e-35 121.9 1.7 3.5e-35 120.9 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.12 GAK64644.1 - 5.6e-06 25.7 3.6 0.00026 20.2 1.8 5.0 3 1 1 4 4 4 2 Autophagy protein Apg17 Hormone_1 PF00103.20 GAK64644.1 - 0.33 10.7 3.7 6.1 6.5 0.2 3.1 2 0 0 2 2 2 0 Somatotropin hormone family FlaC_arch PF05377.11 GAK64644.1 - 3.4 8.2 6.8 41 4.7 0.1 5.3 5 1 0 6 6 6 0 Flagella accessory protein C (FlaC) Ribosomal_L7Ae PF01248.26 GAK64645.1 - 4.3e-24 84.1 0.2 8.4e-24 83.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 GAK64645.1 - 0.0019 18.3 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Cwf_Cwc_15 PF04889.12 GAK64645.1 - 1.1 8.9 12.1 0.16 11.7 8.5 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.10 GAK64645.1 - 3.5 7.9 12.8 1.1 9.5 9.6 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ribonuclease_P PF00825.18 GAK64646.1 - 0.0036 17.4 0.7 0.0036 17.4 0.7 2.0 2 0 0 2 2 2 1 Ribonuclease P PBP PF01161.20 GAK64648.1 - 3e-08 34.0 0.1 5.3e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.32 GAK64649.1 - 3.3e-17 62.5 16.0 4.5e-07 30.5 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 GAK64649.1 - 0.00014 20.7 0.1 0.052 12.2 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 GAK64649.1 - 0.00044 19.9 1.8 0.021 14.4 0.2 2.2 1 1 1 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 GAK64649.1 - 0.0066 16.7 0.0 1.9 8.8 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK64649.1 - 0.0073 15.3 0.0 0.29 10.0 0.0 3.2 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 GAK64649.1 - 0.23 12.0 2.5 46 4.7 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain DUF963 PF06131.11 GAK64649.1 - 0.29 10.6 1.6 0.42 10.1 0.4 1.9 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Clr2 PF10383.9 GAK64651.1 - 1.4e-28 100.5 0.6 1.3e-27 97.4 0.0 2.4 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 GAK64651.1 - 2e-21 76.6 1.0 1.9e-20 73.4 2.5 1.9 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 WW PF00397.26 GAK64651.1 - 3.9e-09 36.4 1.8 7.9e-09 35.5 1.8 1.6 1 0 0 1 1 1 1 WW domain DUF5323 PF17257.2 GAK64651.1 - 0.089 12.7 2.8 1.6 8.7 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5323) SYCE1 PF15233.6 GAK64651.1 - 0.09 12.8 1.4 0.21 11.7 1.4 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 PWWP PF00855.17 GAK64651.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.3 3 0 0 3 3 3 0 PWWP domain zf-CHCC PF10276.9 GAK64651.1 - 1.8 8.7 4.6 2.4 8.3 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger domain DNA_primase_S PF01896.19 GAK64652.1 - 2.6e-50 170.9 0.0 5.3e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 DNA primase small subunit Ist1 PF03398.14 GAK64653.1 - 2.4e-54 183.7 1.6 3e-54 183.3 1.6 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RNA_pol_Rpc4 PF05132.14 GAK64653.1 - 0.021 15.2 0.7 0.034 14.6 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DnaJ PF00226.31 GAK64654.1 - 1.1e-19 70.3 0.5 3.9e-19 68.5 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain SAPS PF04499.15 GAK64654.1 - 0.15 10.9 2.5 0.21 10.3 2.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RrnaAD PF00398.20 GAK64655.1 - 9.6e-20 70.8 0.0 3.2e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pam17 PF08566.10 GAK64656.1 - 1.9e-64 216.5 0.0 2.4e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DEAD PF00270.29 GAK64657.1 - 3.3e-43 147.5 0.2 4.8e-43 146.9 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK64657.1 - 1.8e-27 95.9 0.7 6e-27 94.2 0.3 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 GAK64657.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 GAK64657.1 - 0.0033 17.5 0.0 0.0096 15.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RSN1_7TM PF02714.15 GAK64658.1 - 2.8e-72 243.3 20.9 2.8e-72 243.3 20.9 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAK64658.1 - 7.1e-29 100.6 0.3 7.1e-29 100.6 0.3 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAK64658.1 - 3.2e-25 89.4 0.0 5.7e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter AA_permease PF00324.21 GAK64661.1 - 1.1e-133 446.4 40.1 1.2e-133 446.2 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK64661.1 - 7.2e-41 140.4 43.5 9.5e-41 140.0 43.5 1.2 1 0 0 1 1 1 1 Amino acid permease IBR PF01485.21 GAK64662.1 - 1.6e-20 73.1 43.3 1e-11 44.9 4.3 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GAK64662.1 - 0.00013 21.9 1.6 0.00013 21.9 1.6 3.6 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 GAK64662.1 - 0.00018 21.8 4.8 0.00018 21.8 4.8 4.6 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 GAK64662.1 - 0.0011 18.8 5.3 0.0011 18.8 5.3 4.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK64662.1 - 0.0021 17.9 38.3 0.0048 16.7 3.3 4.7 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAK64662.1 - 0.49 10.6 26.0 0.17 12.1 0.4 4.4 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 GAK64662.1 - 8 6.7 13.8 1.1 9.4 1.7 2.9 2 1 0 2 2 2 0 Zinc-binding RING-finger Ribosomal_L27A PF00828.19 GAK64663.1 - 1.1e-20 74.6 0.0 1.5e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 GAK64663.1 - 0.049 13.7 0.3 0.9 9.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5026) FTHFS PF01268.19 GAK64664.1 - 8.6e-256 849.5 0.3 8.6e-256 849.5 0.3 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 GAK64664.1 - 3.1e-65 218.4 0.3 3.1e-65 218.4 0.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAK64664.1 - 3.9e-36 123.9 0.2 8.6e-36 122.7 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Hexapep PF00132.24 GAK64665.1 - 2.8e-11 42.7 12.9 6.4e-06 25.7 1.8 3.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAK64665.1 - 0.00011 21.8 12.3 0.0096 15.7 0.2 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MPC PF03650.13 GAK64666.1 - 2.8e-42 143.3 0.3 3.4e-42 143.0 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ATP_transf PF09830.9 GAK64667.1 - 5.1e-15 55.4 0.0 9.3e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4134 PF13572.6 GAK64668.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4134) SLC3A2_N PF16028.5 GAK64668.1 - 7.6 6.2 7.7 2.3 7.8 0.1 3.1 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus Metallophos PF00149.28 GAK64669.1 - 6.1e-11 43.2 0.1 1e-10 42.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 GAK64670.1 - 5.1e-60 203.1 0.0 1.3e-35 123.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64670.1 - 4.4e-26 91.7 0.0 5.7e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 GAK64670.1 - 4.8e-10 40.0 5.5 4.9e-10 40.0 2.2 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 GAK64670.1 - 0.0014 17.5 1.2 0.008 15.0 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 GAK64670.1 - 0.0042 16.8 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 GAK64670.1 - 0.07 13.1 0.3 0.45 10.5 0.0 2.4 2 1 0 2 2 2 0 PX domain RRM_1 PF00076.22 GAK64672.1 - 5.6e-31 106.2 0.0 3.7e-19 68.3 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAK64672.1 - 2.2e-14 53.4 1.2 1.9e-07 31.2 0.1 3.4 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 GAK64672.1 - 2.1e-05 24.5 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 UL17 PF17640.2 GAK64672.1 - 0.11 12.6 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized UL17 Nup35_RRM_2 PF14605.6 GAK64672.1 - 0.15 12.1 0.0 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cytochrom_B561 PF03188.16 GAK64673.1 - 1.4e-12 47.9 7.3 1.4e-12 47.9 7.3 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF1345 PF07077.11 GAK64673.1 - 0.36 10.5 15.9 0.058 13.1 3.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) DUF2306 PF10067.9 GAK64673.1 - 1.6 8.9 19.1 0.14 12.3 8.0 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) DUF1516 PF07457.11 GAK64673.1 - 3.3 7.9 9.1 10 6.4 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DUF4079 PF13301.6 GAK64673.1 - 3.7 7.7 17.8 33 4.6 3.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Gpr1_Fun34_YaaH PF01184.19 GAK64674.1 - 1.5e-29 103.1 21.0 1.9e-29 102.8 21.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4807 PF16065.5 GAK64674.1 - 0.2 11.3 0.3 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) Peptidase_M17 PF00883.21 GAK64675.1 - 6e-113 377.2 0.1 9.9e-113 376.5 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain PFU PF09070.11 GAK64675.1 - 3.8e-45 152.8 0.3 7.2e-45 151.9 0.3 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 GAK64675.1 - 1.6e-42 145.6 2.7 2.8e-42 144.9 2.7 1.4 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 GAK64675.1 - 4.1e-29 100.2 14.1 8.9e-08 32.7 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Peptidase_M17_N PF02789.17 GAK64675.1 - 0.0005 19.9 0.2 0.0032 17.3 0.1 2.6 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain 5-FTHF_cyc-lig PF01812.20 GAK64676.1 - 1.3e-38 132.7 0.0 1.6e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Pribosyltran_N PF13793.6 GAK64677.1 - 3e-43 146.5 0.0 1.7e-42 144.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAK64677.1 - 1.3e-36 126.3 1.4 2e-32 112.7 0.4 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAK64677.1 - 2.8e-15 56.2 0.9 3.3e-08 33.2 0.4 2.9 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.6 GAK64677.1 - 0.0092 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase PF00069.25 GAK64678.1 - 1.1e-67 228.2 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64678.1 - 2.3e-34 118.9 0.0 7.5e-34 117.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAK64678.1 - 0.0006 18.9 0.1 0.00091 18.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAK64678.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAK64678.1 - 0.002 17.5 0.3 0.0042 16.5 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK64678.1 - 0.0047 16.9 0.2 0.024 14.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAK64678.1 - 0.068 11.9 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 GAK64678.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YukC PF10140.9 GAK64678.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CYSTM PF12734.7 GAK64679.1 - 0.25 11.7 1.5 0.94 9.8 1.5 2.0 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance GCP_C_terminal PF04130.13 GAK64680.1 - 1e-17 64.6 1.5 1.3e-17 64.3 0.2 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAK64680.1 - 5.5e-14 52.5 0.0 9.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal PIG-S PF10510.9 GAK64680.1 - 0.067 12.0 1.2 0.18 10.6 0.6 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF4746 PF15928.5 GAK64680.1 - 1.3 8.4 7.2 3.5 7.0 7.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MOZ_SAS PF01853.18 GAK64681.1 - 1.3e-74 249.8 0.0 1.8e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAK64681.1 - 1.8e-20 72.3 1.3 4.7e-20 70.9 1.3 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 GAK64681.1 - 4.3e-17 61.7 24.1 9e-10 38.3 8.9 3.3 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 GAK64681.1 - 7.5e-05 22.7 5.4 7.5e-05 22.7 5.4 3.0 1 1 1 2 2 2 1 PHD-finger SAPS PF04499.15 GAK64682.1 - 2.6e-175 583.9 0.1 2e-174 581.0 0.0 2.3 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Cas9_REC PF16592.5 GAK64682.1 - 0.13 10.9 0.4 0.2 10.3 0.4 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 MscS_TM PF12794.7 GAK64682.1 - 0.2 10.5 3.1 0.31 9.8 3.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MAS20 PF02064.15 GAK64682.1 - 7.3 6.7 7.6 84 3.3 5.1 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor Profilin PF00235.19 GAK64683.1 - 1.9e-44 151.0 0.1 2.1e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 Profilin TIM PF00121.18 GAK64684.1 - 6.6e-96 320.4 0.5 7.9e-96 320.1 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 GAK64684.1 - 0.00015 21.3 0.1 0.00077 19.0 0.0 1.9 1 1 1 2 2 2 1 CutC family Glyco_transf_41 PF13844.6 GAK64684.1 - 0.0068 14.9 0.1 0.012 14.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 41 MEDS PF14417.6 GAK64684.1 - 0.018 14.9 0.9 1.6 8.5 0.3 2.6 1 1 1 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF5403 PF17395.2 GAK64684.1 - 0.071 13.4 0.7 0.18 12.1 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5403) Thiolase_N PF00108.23 GAK64685.1 - 9.7e-79 264.4 0.8 1.6e-78 263.7 0.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAK64685.1 - 3.2e-48 162.4 0.4 3.2e-48 162.4 0.4 2.1 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAK64685.1 - 7.3e-05 22.5 1.2 0.00023 20.9 1.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain bZIP_1 PF00170.21 GAK64686.1 - 9.3e-05 22.4 13.6 0.00016 21.7 13.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor Ribosomal_L27e PF01777.18 GAK64686.1 - 0.063 13.6 0.4 0.11 12.8 0.4 1.3 1 0 0 1 1 1 0 Ribosomal L27e protein family bZIP_Maf PF03131.17 GAK64686.1 - 0.82 10.2 12.1 1.4 9.5 12.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_L37 PF08561.10 GAK64686.1 - 6.3 7.3 6.4 12 6.4 6.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Ribosomal_S21 PF01165.20 GAK64687.1 - 0.017 14.8 0.3 0.047 13.4 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S21 PhoLip_ATPase_C PF16212.5 GAK64689.1 - 1.8e-71 240.9 30.1 1.8e-71 240.9 30.1 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAK64689.1 - 2.7e-21 75.0 4.4 2.7e-21 75.0 4.4 3.0 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAK64689.1 - 3.7e-12 47.0 0.5 7.9e-07 29.6 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAK64689.1 - 1.2e-11 44.6 0.0 3.2e-10 39.9 0.0 3.0 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAK64689.1 - 0.0003 20.6 0.3 0.0086 15.8 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAK64689.1 - 0.00069 19.2 0.0 0.00069 19.2 0.0 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Mei5_like PF17021.5 GAK64689.1 - 0.042 13.9 0.1 0.66 10.0 0.3 2.4 2 0 0 2 2 2 0 Putative double-strand recombination repair-like zf-UBR PF02207.20 GAK64690.1 - 6.3e-11 42.3 8.7 6.3e-11 42.3 8.7 2.9 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 GAK64690.1 - 0.00035 20.4 1.3 0.00035 20.4 1.3 3.8 4 1 1 5 5 5 1 PHD-finger PHD_4 PF16866.5 GAK64690.1 - 0.068 13.3 0.6 0.068 13.3 0.6 2.3 2 0 0 2 2 2 0 PHD-finger Pyrid_oxidase_2 PF13883.6 GAK64691.1 - 5e-24 85.2 0.1 6.4e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rad51 PF08423.11 GAK64692.1 - 3.7e-128 426.2 0.0 4.4e-128 425.9 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAK64692.1 - 3.3e-11 43.1 0.0 4.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 GAK64692.1 - 1.7e-09 37.5 0.1 2.4e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 GAK64692.1 - 1.2e-06 28.1 0.1 2.8e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 GAK64692.1 - 1.5e-06 28.7 0.2 4.5e-06 27.2 0.3 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 GAK64692.1 - 0.0019 17.6 0.1 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 GAK64692.1 - 0.0072 15.5 0.8 0.35 9.9 0.8 2.1 1 1 1 2 2 2 1 PAXNEB protein AAA_24 PF13479.6 GAK64692.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 GAK64692.1 - 0.12 12.4 0.3 0.29 11.2 0.3 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain PNRC PF15365.6 GAK64693.1 - 5.9e-06 25.9 7.4 5.9e-06 25.9 7.4 3.0 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif CBFD_NFYB_HMF PF00808.23 GAK64694.1 - 1.7e-09 37.8 0.1 3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VRR_NUC PF08774.11 GAK64695.1 - 7.5e-23 80.7 0.0 1.7e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Rho_N PF07498.12 GAK64695.1 - 0.098 12.6 0.4 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Myosin_head PF00063.21 GAK64696.1 - 4.9e-269 894.2 0.0 4.9e-269 894.2 0.0 2.7 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 GAK64696.1 - 3.9e-09 35.0 135.9 3.9e-09 35.0 135.9 3.4 3 1 0 3 3 3 1 Myosin tail Myosin_N PF02736.19 GAK64696.1 - 2.1e-08 33.9 0.1 4.5e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Lebercilin PF15619.6 GAK64696.1 - 0.003 17.2 24.8 0.003 17.2 24.8 7.6 4 1 3 7 7 7 2 Ciliary protein causing Leber congenital amaurosis disease AAA_22 PF13401.6 GAK64696.1 - 0.13 12.5 0.0 0.13 12.5 0.0 4.8 6 1 0 6 6 6 0 AAA domain Erf4 PF10256.9 GAK64696.1 - 0.14 12.2 0.1 0.8 9.8 0.1 2.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family AAA_19 PF13245.6 GAK64696.1 - 0.17 12.2 0.0 0.17 12.2 0.0 3.7 4 1 0 4 4 4 0 AAA domain RabGAP-TBC PF00566.18 GAK64697.1 - 2.8e-18 66.4 0.0 1.4e-10 41.2 0.1 3.3 3 0 0 3 3 3 3 Rab-GTPase-TBC domain Chromo PF00385.24 GAK64698.1 - 3.1e-13 49.4 2.6 3.1e-13 49.4 2.6 2.4 2 1 2 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 GAK64698.1 - 1.8e-09 37.6 0.3 2.3e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain DUF3759 PF12585.8 GAK64699.1 - 3e-35 120.1 6.2 3.4e-35 119.9 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) PfkB PF00294.24 GAK64701.1 - 8.5e-08 31.8 0.1 0.00017 21.0 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase WD40 PF00400.32 GAK64703.1 - 2.1e-55 183.4 17.8 5.6e-09 36.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 GAK64703.1 - 1.8e-26 92.3 5.1 2.8e-26 91.6 5.1 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 GAK64703.1 - 8.7e-24 83.6 0.7 7.6e-06 26.2 0.0 6.4 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAK64703.1 - 6.6e-11 42.1 0.0 0.0013 18.2 0.0 4.2 5 0 0 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 GAK64703.1 - 1.3e-07 31.0 0.7 0.52 9.2 0.0 5.8 2 2 5 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAK64703.1 - 3e-05 22.9 0.3 0.85 8.2 0.0 3.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 GAK64703.1 - 0.00059 19.7 0.0 16 5.5 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 GAK64703.1 - 0.0018 17.7 0.2 0.76 9.1 0.0 3.7 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 GAK64703.1 - 0.0019 16.8 0.2 0.56 8.7 0.0 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain DUF5046 PF16465.5 GAK64703.1 - 0.0065 16.0 0.1 0.97 8.8 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5046) DUF1391 PF07151.12 GAK64703.1 - 0.02 14.7 0.3 0.041 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) GAS PF13851.6 GAK64703.1 - 0.028 13.8 0.5 0.049 13.0 0.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bystin PF05291.11 GAK64704.1 - 2.9e-132 440.3 0.0 4.1e-132 439.9 0.0 1.1 1 0 0 1 1 1 1 Bystin Ribosomal_L15e PF00827.17 GAK64704.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L15 GPP34 PF05719.11 GAK64705.1 - 1.1e-74 250.9 0.0 1.4e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) POP1 PF06978.11 GAK64706.1 - 3.4e-25 89.2 33.6 3.6e-16 59.8 9.3 3.7 3 1 1 4 4 4 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 GAK64706.1 - 1.9e-19 69.8 0.1 1.9e-19 69.8 0.1 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain MITF_TFEB_C_3_N PF15951.5 GAK64706.1 - 0.11 13.1 3.4 0.31 11.7 3.4 1.7 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus FSA_C PF10479.9 GAK64706.1 - 0.31 9.1 3.4 0.48 8.5 3.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sec20 PF03908.13 GAK64707.1 - 0.11 12.4 1.0 0.25 11.3 1.0 1.5 1 0 0 1 1 1 0 Sec20 SRP40_C PF05022.12 GAK64708.1 - 1.8e-28 99.2 0.9 4.1e-28 98.0 0.9 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain adh_short PF00106.25 GAK64709.1 - 1.7e-34 119.0 0.0 2.2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK64709.1 - 9.7e-26 90.8 0.0 1.8e-25 89.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK64709.1 - 2.6e-08 34.0 0.1 1.6e-05 24.9 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAK64709.1 - 0.21 11.0 0.1 0.38 10.2 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Kelch_4 PF13418.6 GAK64711.1 - 6.5e-37 125.3 11.1 2.1e-05 24.4 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 GAK64711.1 - 2.3e-32 110.3 1.1 3.9e-06 26.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAK64711.1 - 3.9e-32 109.7 3.6 1.7e-05 24.7 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAK64711.1 - 5.6e-30 103.0 5.8 2.3e-07 30.9 0.0 6.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAK64711.1 - 5.5e-28 95.9 10.3 1.1e-06 28.3 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAK64711.1 - 2.4e-24 84.7 11.0 9.2e-06 25.8 0.1 6.1 4 1 2 6 6 6 5 Kelch motif PQQ_3 PF13570.6 GAK64711.1 - 0.04 14.4 0.3 12 6.5 0.0 3.7 3 1 1 4 4 4 0 PQQ-like domain Adaptin_N PF01602.20 GAK64712.1 - 1.4e-96 324.2 1.7 3.2e-83 280.1 2.3 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GAK64712.1 - 1.7e-17 63.9 1.2 8.4e-16 58.4 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAK64712.1 - 7.6e-05 23.0 18.4 0.00012 22.4 0.3 6.0 7 0 0 7 7 7 1 HEAT repeats HEAT PF02985.22 GAK64712.1 - 0.017 15.3 12.4 1.4 9.4 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat RTP1_C1 PF10363.9 GAK64712.1 - 0.46 10.7 1.9 6.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 PPP4R2 PF09184.11 GAK64712.1 - 1.6 8.3 14.8 3.8 7.0 14.8 1.7 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 GAK64712.1 - 4.7 7.1 14.4 0.47 10.4 9.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Gar1 PF04410.14 GAK64714.1 - 5.8e-29 100.9 8.6 1.1e-28 99.9 0.0 3.4 3 0 0 3 3 3 2 Gar1/Naf1 RNA binding region zf-AN1 PF01428.16 GAK64714.1 - 1.1e-13 51.1 20.1 9.8e-10 38.4 3.9 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger Unstab_antitox PF09720.10 GAK64714.1 - 0.0025 17.9 1.3 0.0077 16.3 1.3 1.9 1 0 0 1 1 1 1 Putative addiction module component Transp_Tc5_C PF04236.15 GAK64714.1 - 2.1 8.8 15.2 0.1 13.0 2.8 3.2 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Malate_synthase PF01274.22 GAK64715.1 - 6e-207 688.1 0.0 9.1e-207 687.5 0.0 1.2 1 0 0 1 1 1 1 Malate synthase Thioredoxin PF00085.20 GAK64715.1 - 2.3e-25 88.6 0.0 4.2e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAK64715.1 - 0.00031 21.1 0.1 0.0016 18.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAK64715.1 - 0.0029 17.4 0.1 0.0057 16.4 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAK64715.1 - 0.0039 17.5 0.0 0.16 12.3 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 GAK64715.1 - 0.004 17.1 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 GAK64715.1 - 0.0046 16.3 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GAK64715.1 - 0.024 14.8 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 GAK64715.1 - 0.037 13.7 0.2 0.59 9.8 0.3 2.3 1 1 0 1 1 1 0 Redoxin HATPase_c PF02518.26 GAK64716.1 - 1.9e-29 102.4 0.0 3.9e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAK64716.1 - 4.9e-25 87.9 0.0 1.3e-24 86.5 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 GAK64716.1 - 3.4e-21 75.6 3.2 2.1e-06 27.9 0.0 4.5 4 0 0 4 4 4 3 PAS fold HisKA PF00512.25 GAK64716.1 - 7.7e-19 67.5 0.2 3.4e-18 65.4 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 GAK64716.1 - 5.1e-14 52.3 4.2 8.1e-14 51.7 2.9 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 GAK64716.1 - 8.9e-12 45.0 1.0 0.0014 18.6 0.0 5.0 5 0 0 5 5 5 2 PAS fold PAS_9 PF13426.7 GAK64716.1 - 3.8e-08 33.5 0.0 7.7e-05 22.9 0.0 4.3 4 0 0 4 4 4 1 PAS domain PAS_8 PF13188.7 GAK64716.1 - 7.8e-06 25.8 0.1 0.17 12.0 0.0 3.8 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.6 GAK64716.1 - 0.025 14.7 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.7 GAK64716.1 - 0.032 14.4 0.5 9.4 6.4 0.0 3.8 4 0 0 4 4 4 0 PAS fold AAA_31 PF13614.6 GAK64716.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain HATPase_c_3 PF13589.6 GAK64716.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DEAD PF00270.29 GAK64717.1 - 7.4e-42 143.1 0.0 3.1e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.6 GAK64717.1 - 3.8e-23 81.5 0.0 1.1e-22 79.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 GAK64717.1 - 1.2e-18 67.5 0.0 5.5e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK64717.1 - 4.4e-05 23.5 0.0 0.00018 21.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAK64717.1 - 0.011 15.2 4.7 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain SbcCD_C PF13558.6 GAK64717.1 - 0.034 14.4 0.1 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NUDIX PF00293.28 GAK64717.1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain AAA_22 PF13401.6 GAK64717.1 - 0.087 13.1 0.0 0.61 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain SPX PF03105.19 GAK64718.1 - 1.8e-86 291.5 23.9 6.1e-85 286.5 23.9 2.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 GAK64718.1 - 8.1e-08 32.0 5.7 1.4e-07 31.3 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK64718.1 - 1.8e-07 30.9 4.7 2.9e-07 30.2 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAK64718.1 - 5.4e-06 26.6 7.7 8.9e-06 25.9 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAK64718.1 - 9.9e-06 25.6 6.1 1.7e-05 24.9 6.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAK64718.1 - 6.5e-05 22.7 6.4 0.00012 21.9 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAK64718.1 - 0.00011 22.0 7.7 0.00018 21.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK64718.1 - 0.0002 21.2 5.7 0.00037 20.4 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK64718.1 - 0.00093 19.2 7.3 0.0018 18.2 7.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAK64718.1 - 0.0094 15.7 2.1 0.019 14.7 2.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 GAK64718.1 - 0.015 15.2 2.4 0.035 14.0 2.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAK64718.1 - 0.077 13.3 6.1 0.2 12.0 6.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 GAK64718.1 - 0.45 10.7 4.2 1 9.5 4.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 GMC_oxred_N PF00732.19 GAK64719.1 - 8.1e-48 163.3 0.0 1.2e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK64719.1 - 6.7e-40 136.9 0.1 1.1e-39 136.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAK64719.1 - 0.00013 22.1 0.1 0.00035 20.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK64719.1 - 0.00082 19.1 0.1 0.0044 16.6 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAK64719.1 - 0.0021 17.4 0.0 0.77 8.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK64719.1 - 0.0031 16.7 0.1 0.0055 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAK64719.1 - 0.0075 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAK64719.1 - 0.013 14.5 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAK64719.1 - 0.023 14.0 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK64719.1 - 0.15 10.7 0.1 0.24 10.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein COG5 PF10392.9 GAK64720.1 - 7.4e-19 68.2 3.4 1.9e-16 60.5 2.4 3.1 2 0 0 2 2 2 2 Golgi transport complex subunit 5 TAF1_subA PF14929.6 GAK64720.1 - 0.051 13.0 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A COG2 PF06148.11 GAK64720.1 - 0.086 12.9 1.5 1.8 8.7 1.1 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V-SNARE PF05008.15 GAK64720.1 - 0.093 13.1 0.2 0.29 11.5 0.2 1.9 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Vps51 PF08700.11 GAK64720.1 - 0.3 11.2 1.3 8.9 6.5 0.7 2.5 2 0 0 2 2 2 0 Vps51/Vps67 dCMP_cyt_deam_1 PF00383.23 GAK64721.1 - 7.6e-26 89.9 2.4 1.2e-25 89.3 2.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAK64721.1 - 8.1e-14 51.6 0.6 1.4e-13 50.8 0.6 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_33 PF13671.6 GAK64721.1 - 0.00022 21.4 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SNAD4 PF18750.1 GAK64721.1 - 0.0019 18.3 0.3 0.0035 17.4 0.3 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 GAK64721.1 - 0.0057 16.6 0.4 0.0091 15.9 0.4 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain AAA_18 PF13238.6 GAK64721.1 - 0.0075 16.8 0.0 0.015 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain NAD1 PF18778.1 GAK64721.1 - 0.0082 16.3 0.6 0.013 15.6 0.6 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 Cytidylate_kin PF02224.18 GAK64721.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase APOBEC3 PF18771.1 GAK64721.1 - 0.014 15.5 0.2 0.027 14.6 0.2 1.5 1 0 0 1 1 1 0 APOBEC3 AAA PF00004.29 GAK64721.1 - 0.025 15.0 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APOBEC2 PF18772.1 GAK64721.1 - 0.068 13.2 0.5 0.12 12.5 0.5 1.3 1 0 0 1 1 1 0 APOBEC2 TFIIIC_sub6 PF10419.9 GAK64723.1 - 2e-18 66.0 0.0 3.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Rpn3_C PF08375.11 GAK64724.1 - 2e-27 95.4 0.8 7.8e-27 93.5 0.8 2.1 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 GAK64724.1 - 4e-17 62.6 0.2 1.1e-16 61.3 0.2 1.7 1 0 0 1 1 1 1 PCI domain NT-C2 PF10358.9 GAK64724.1 - 1.4e-08 34.6 0.2 0.044 13.5 0.0 4.3 4 0 0 4 4 4 3 N-terminal C2 in EEIG1 and EHBP1 proteins PH_9 PF15410.6 GAK64725.1 - 2.6e-08 34.3 0.1 1.3e-07 32.0 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAK64725.1 - 5.2e-07 30.1 0.0 1e-05 26.0 0.0 2.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 GAK64725.1 - 0.034 14.6 0.1 0.25 11.8 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Bestrophin PF01062.21 GAK64726.1 - 4e-20 72.4 0.0 5.2e-19 68.7 0.0 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel NUDIX PF00293.28 GAK64727.1 - 1e-07 32.1 0.0 2.1e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Peptidase_M16_M PF16187.5 GAK64728.1 - 1.8e-97 326.0 0.2 2.7e-97 325.4 0.2 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAK64728.1 - 8.9e-44 149.1 1.1 1.7e-41 141.7 0.0 3.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAK64728.1 - 5.9e-31 107.9 0.1 2.3e-20 73.4 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Aa_trans PF01490.18 GAK64728.1 - 3.3e-26 92.0 36.9 3.3e-26 92.0 36.9 1.6 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein DUF2061 PF09834.9 GAK64728.1 - 0.0086 16.6 4.9 0.068 13.7 0.8 3.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2061) DUF4397 PF14344.6 GAK64728.1 - 0.12 13.2 0.0 0.34 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) tRNA-synt_1b PF00579.25 GAK64729.1 - 2.9e-73 246.8 0.0 3.9e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FmiP_Thoc5 PF09766.9 GAK64730.1 - 1.2e-30 107.1 16.3 1.6e-30 106.6 16.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SWIRM-assoc_1 PF16495.5 GAK64730.1 - 0.043 13.8 9.6 0.98 9.4 1.9 3.3 2 2 1 3 3 3 0 SWIRM-associated region 1 DUF4706 PF15797.5 GAK64730.1 - 0.13 12.8 1.1 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) HEPN_SAV2148 PF18725.1 GAK64730.1 - 0.16 11.4 3.3 0.089 12.2 1.1 1.6 2 0 0 2 2 2 0 SAV2148-like HEPN AAA_23 PF13476.6 GAK64730.1 - 0.27 11.7 10.8 0.36 11.3 10.8 1.2 1 0 0 1 1 1 0 AAA domain SPA PF08616.10 GAK64731.1 - 8.6e-34 115.9 0.0 1.7e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 GAK64731.1 - 4.6e-22 78.9 0.1 2.7e-21 76.5 0.1 2.1 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 GAK64731.1 - 3.6e-08 32.5 0.1 0.015 14.0 0.0 3.6 3 2 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 GAK64731.1 - 0.0011 18.6 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Peptidase_C50 PF03568.17 GAK64733.1 - 3.1e-114 382.2 0.0 8.6e-114 380.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase family C50 TPR_8 PF13181.6 GAK64733.1 - 0.00017 21.5 0.9 34 5.0 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAK64733.1 - 0.0014 18.5 0.4 0.9 9.7 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAK64733.1 - 0.032 14.9 7.2 0.51 11.1 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64733.1 - 0.071 13.4 0.1 27 5.1 0.0 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAK64733.1 - 2 9.0 7.3 5.1 7.7 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SNF2_N PF00176.23 GAK64734.1 - 8.9e-56 189.1 0.1 1.5e-54 185.0 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK64734.1 - 1.4e-15 57.6 0.0 5.4e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK64734.1 - 2.9e-10 40.4 0.1 6.7e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAK64734.1 - 2.5e-07 30.6 0.0 6.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 GAK64734.1 - 5.8e-07 29.3 5.5 5.8e-07 29.3 5.5 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK64734.1 - 2.9e-06 27.0 6.6 2.9e-06 27.0 6.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK64734.1 - 8.8e-06 25.5 5.4 8.8e-06 25.5 5.4 2.3 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAK64734.1 - 8.8e-06 25.5 6.0 8.8e-06 25.5 6.0 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAK64734.1 - 3.6e-05 24.0 7.9 3.6e-05 24.0 7.9 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAK64734.1 - 0.00026 20.9 6.7 0.00026 20.9 6.7 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK64734.1 - 0.0071 16.4 2.8 0.0071 16.4 2.8 2.8 2 1 1 3 3 2 1 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 GAK64734.1 - 0.035 13.3 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Zn_Tnp_IS91 PF14319.6 GAK64734.1 - 0.059 13.4 12.7 0.13 12.3 1.6 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-ANAPC11 PF12861.7 GAK64734.1 - 0.089 12.9 1.8 0.22 11.6 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAK64734.1 - 0.46 10.4 3.0 1 9.3 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ald_Xan_dh_C2 PF02738.18 GAK64735.1 - 2.6e-196 653.4 0.2 3.6e-196 652.9 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 GAK64735.1 - 3.5e-37 127.8 0.0 1.4e-36 125.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 GAK64735.1 - 1.6e-34 118.6 0.1 3.4e-34 117.5 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 GAK64735.1 - 2.1e-27 95.3 0.0 5.1e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 GAK64735.1 - 1.3e-25 89.2 0.1 3.6e-25 87.8 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 GAK64735.1 - 1.6e-06 28.0 0.0 5.1e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Velvet PF11754.8 GAK64736.1 - 2.3e-20 73.6 1.3 1.5e-16 61.1 0.1 4.6 3 2 1 4 4 4 2 Velvet factor Cwf_Cwc_15 PF04889.12 GAK64737.1 - 0.054 13.2 9.6 0.077 12.7 9.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YjbE PF11106.8 GAK64737.1 - 0.21 11.8 3.5 0.47 10.7 3.5 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE PBP1_TM PF14812.6 GAK64737.1 - 0.62 10.5 9.0 1.3 9.4 9.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 GAK64737.1 - 1.9 8.6 8.8 3 7.9 8.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Med8 PF10232.9 GAK64737.1 - 4.8 6.7 6.1 1.5 8.3 0.3 2.4 2 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 RRN3 PF05327.11 GAK64737.1 - 6.9 5.1 11.0 2.7 6.4 8.5 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GAK64737.1 - 6.9 4.6 9.9 13 3.7 9.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi Lgl_C PF08596.10 GAK64738.1 - 3.9e-23 81.8 0.0 1.7e-18 66.5 0.0 2.4 2 1 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 GAK64738.1 - 3.4e-06 27.3 0.0 0.019 15.2 0.0 3.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GAK64738.1 - 0.12 10.7 0.0 10 4.3 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 GAK64738.1 - 0.15 13.0 9.3 0.2 12.6 0.1 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat Glyco_transf_20 PF00982.21 GAK64739.1 - 4.2e-153 510.4 0.0 6.8e-153 509.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAK64739.1 - 2.1e-65 220.1 0.0 4.7e-65 219.0 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase ING PF12998.7 GAK64740.1 - 1.3e-15 57.8 0.0 4.8e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAK64740.1 - 0.0001 22.1 7.9 0.00018 21.3 7.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAK64740.1 - 0.0054 16.3 1.1 0.0095 15.5 1.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-C4pol PF14260.6 GAK64740.1 - 2.9 8.4 4.6 1.1 9.8 1.8 1.7 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta SMC_N PF02463.19 GAK64741.1 - 2.6e-64 216.7 0.0 2.3e-63 213.6 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAK64741.1 - 4.1e-29 101.3 0.3 1.6e-28 99.3 0.2 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAK64741.1 - 4.6e-17 62.8 3.9 9.8e-10 38.7 0.0 3.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAK64741.1 - 3.7e-13 50.4 6.8 3.7e-13 50.4 6.8 6.0 3 2 2 5 5 3 1 AAA domain AAA_15 PF13175.6 GAK64741.1 - 2e-11 44.2 3.1 2e-11 44.2 3.1 3.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 GAK64741.1 - 2.8e-08 33.4 0.0 6.8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAK64741.1 - 0.0027 17.9 0.0 0.01 16.0 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit TetR_C_5 PF08360.11 GAK64741.1 - 0.028 14.6 0.1 0.36 11.0 0.1 2.5 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Clavanin PF05452.11 GAK64741.1 - 0.15 12.3 0.1 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Clavanin NPV_P10 PF05531.12 GAK64741.1 - 0.18 12.3 23.8 16 6.1 0.2 6.8 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 GAK64741.1 - 0.25 8.8 99.3 0.063 10.8 35.6 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3584) Amidase PF01425.21 GAK64741.1 - 1.9 7.3 12.3 0.14 11.1 6.6 1.9 2 0 0 2 2 2 0 Amidase DUF1664 PF07889.12 GAK64741.1 - 3.9 7.5 40.2 0.66 10.0 0.9 7.1 5 2 3 8 8 8 0 Protein of unknown function (DUF1664) DUF4653 PF15546.6 GAK64742.1 - 0.078 12.6 1.7 0.16 11.6 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Mito_fiss_reg PF05308.11 GAK64742.1 - 9.4 6.2 8.1 2.1 8.4 0.7 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator KH_8 PF17903.1 GAK64743.1 - 5.5e-32 109.7 0.0 1.1e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 GAK64743.1 - 0.00016 21.5 0.1 0.00036 20.3 0.1 1.6 1 0 0 1 1 1 1 KH domain GRAB PF10375.9 GAK64744.1 - 6.4e-08 32.2 0.7 6.4e-08 32.2 0.7 2.4 2 0 0 2 2 2 1 GRIP-related Arf-binding domain DUF4407 PF14362.6 GAK64744.1 - 0.00031 20.2 9.9 0.00031 20.2 9.9 3.1 1 1 2 3 3 2 1 Domain of unknown function (DUF4407) Filament PF00038.21 GAK64744.1 - 0.004 16.8 8.6 0.004 16.8 8.6 2.4 1 1 1 2 2 2 1 Intermediate filament protein SlyX PF04102.12 GAK64744.1 - 0.012 16.2 1.2 0.012 16.2 1.2 5.7 3 2 2 6 6 5 0 SlyX Atg14 PF10186.9 GAK64744.1 - 0.027 13.6 35.7 0.29 10.2 20.5 2.8 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 GAK64744.1 - 0.036 14.2 0.2 0.036 14.2 0.2 4.0 5 0 0 5 5 4 0 bZIP transcription factor BLOC1_2 PF10046.9 GAK64744.1 - 0.18 12.2 6.6 0.3 11.4 0.5 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GAK64744.1 - 0.48 10.9 3.6 9 6.8 0.6 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAK64744.1 - 0.52 10.3 8.6 0.29 11.2 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 GAK64744.1 - 0.66 8.9 23.5 1.1 8.1 4.4 3.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 GAK64744.1 - 0.76 10.2 7.2 0.97 9.9 0.3 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 GAK64744.1 - 1.6 9.4 14.5 0.14 12.8 0.7 4.0 2 2 2 4 4 4 0 Initiation control protein YabA Tup_N PF08581.10 GAK64744.1 - 2.1 8.7 10.2 0.34 11.2 1.1 3.7 3 1 0 3 3 3 0 Tup N-terminal Noelin-1 PF12308.8 GAK64744.1 - 2.1 8.4 6.2 0.68 9.9 1.4 2.6 2 2 1 3 3 3 0 Neurogenesis glycoprotein XhlA PF10779.9 GAK64744.1 - 2.6 8.3 9.4 8.1 6.7 0.1 3.9 3 1 2 5 5 5 0 Haemolysin XhlA TPP_enzyme_N PF02776.18 GAK64745.1 - 4.6e-52 176.1 0.0 4.6e-52 176.1 0.0 3.1 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAK64745.1 - 2.4e-48 163.8 0.1 8.4e-47 158.8 0.1 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAK64745.1 - 3e-40 137.1 2.3 4.2e-40 136.6 0.1 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 GAK64745.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Dor1 PF04124.12 GAK64746.1 - 4.7e-18 65.0 3.1 4.2e-14 52.0 2.2 2.7 2 1 0 2 2 2 2 Dor1-like family Ribosomal_S10 PF00338.22 GAK64747.1 - 9.9e-29 99.5 0.5 1.2e-28 99.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribophorin_II PF05817.14 GAK64748.1 - 1.9e-06 26.8 0.1 2.9e-05 22.8 0.1 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II Bax1-I PF01027.20 GAK64748.1 - 0.79 9.5 6.7 0.1 12.4 2.2 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 BTB PF00651.31 GAK64749.1 - 1.5e-12 47.7 0.2 1.6e-09 38.0 0.0 3.5 4 0 0 4 4 4 1 BTB/POZ domain CAP_GLY PF01302.25 GAK64749.1 - 1.6e-06 28.0 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Pkinase PF00069.25 GAK64750.1 - 4.8e-71 239.2 0.0 6.4e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64750.1 - 1.8e-41 142.1 0.0 2.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 GAK64750.1 - 4.7e-31 106.8 0.0 2.2e-17 63.0 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 GAK64750.1 - 1.4e-07 31.2 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAK64750.1 - 4.4e-05 22.4 0.1 8.2e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAK64750.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4520 PF15016.6 GAK64750.1 - 0.095 12.8 0.0 5.5 7.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4520) Kdo PF06293.14 GAK64750.1 - 0.31 10.4 1.2 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.21 GAK64751.1 - 3.2e-45 154.6 0.0 3.7e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 GAK64752.1 - 9.4e-17 60.6 0.0 1.7e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK64752.1 - 0.0007 19.7 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif DUF4157 PF13699.6 GAK64752.1 - 0.033 14.4 0.2 0.83 9.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) Nup35_RRM_2 PF14605.6 GAK64752.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF5082 PF16888.5 GAK64753.1 - 0.0098 16.2 1.2 0.023 15.0 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 GAK64753.1 - 0.087 12.4 1.8 0.72 9.4 0.2 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 GAK64753.1 - 0.087 12.9 9.2 2.4 8.2 2.9 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 GAK64753.1 - 2.9 7.6 8.1 2.1 8.1 3.4 2.8 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain T3SS_needle_E PF08988.10 GAK64753.1 - 4.5 7.5 6.5 26 5.1 0.0 3.3 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle PhoLip_ATPase_C PF16212.5 GAK64756.1 - 4.8e-66 223.1 23.9 4.8e-66 223.1 23.9 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAK64756.1 - 3.6e-22 77.8 0.3 8.6e-22 76.6 0.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAK64756.1 - 9.1e-14 52.2 1.6 1.1e-06 29.1 0.3 4.0 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAK64756.1 - 1e-11 44.8 0.0 4.2e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAK64756.1 - 3.5e-07 29.9 0.1 2.5e-06 27.2 0.1 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAK64756.1 - 0.0019 18.0 0.3 0.011 15.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 GAK64757.1 - 3e-22 79.1 0.1 3e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK64757.1 - 6.1e-15 55.4 0.0 1.3e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAK64757.1 - 0.00044 19.8 0.2 0.0013 18.2 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAK64757.1 - 0.0055 16.6 2.9 0.06 13.2 2.9 2.1 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAK64757.1 - 0.088 12.1 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.24 GAK64760.1 - 1.2e-35 123.7 2.0 1.9e-35 123.1 2.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK64760.1 - 0.00018 21.5 0.1 0.0096 15.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAK64760.1 - 0.0015 17.9 0.0 0.087 12.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK64760.1 - 0.0018 18.4 0.7 0.018 15.2 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAK64760.1 - 0.0028 16.9 0.0 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK64760.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 GAK64760.1 - 0.097 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 MCRA family ECH_1 PF00378.20 GAK64761.1 - 9.4e-24 84.1 0.3 1.2e-23 83.7 0.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK64761.1 - 1.1e-06 28.4 0.1 1.6e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ctr PF04145.15 GAK64762.1 - 2.1e-29 103.1 0.3 2.4e-29 102.8 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Bromodomain PF00439.25 GAK64763.1 - 3.6e-32 110.3 1.2 1.7e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 Bromodomain DDHD PF02862.17 GAK64763.1 - 0.99 9.5 14.3 0.13 12.5 8.6 2.2 2 0 0 2 2 2 0 DDHD domain SCAMP PF04144.13 GAK64764.1 - 1.3e-51 175.3 6.8 1.6e-51 175.1 6.8 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 GAK64764.1 - 0.03 13.8 0.6 0.045 13.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4200 PF13863.6 GAK64764.1 - 0.093 13.1 1.7 0.14 12.5 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Peptidase_U4 PF03419.13 GAK64764.1 - 0.3 10.3 7.1 0.41 9.9 7.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Septin PF00735.18 GAK64765.1 - 5.3e-113 377.0 0.9 6.7e-113 376.6 0.9 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAK64765.1 - 8.4e-09 35.5 0.1 2e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK64765.1 - 1.6e-06 28.1 0.2 1.7e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 GAK64765.1 - 3e-05 23.4 0.4 7.3e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 GAK64765.1 - 4.3e-05 23.6 0.3 0.12 12.5 0.1 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 GAK64765.1 - 5.4e-05 22.8 0.9 0.0016 18.0 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 GAK64765.1 - 0.0011 18.3 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAK64765.1 - 0.0014 19.0 0.4 0.0036 17.7 0.0 1.8 3 0 0 3 3 2 1 AAA ATPase domain IIGP PF05049.13 GAK64765.1 - 0.0017 17.5 0.0 0.0041 16.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 GAK64765.1 - 0.0018 18.8 0.3 0.0064 17.0 0.0 2.0 2 1 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.18 GAK64765.1 - 0.0019 17.6 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 GAK64765.1 - 0.0026 17.3 0.1 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 GAK64765.1 - 0.0054 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAK64765.1 - 0.0063 16.8 0.0 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAK64765.1 - 0.0069 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 GAK64765.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 GAK64765.1 - 0.034 13.5 0.3 0.26 10.6 0.3 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 GAK64765.1 - 0.07 12.8 0.4 0.19 11.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain Microtub_bd PF16796.5 GAK64765.1 - 0.075 13.0 0.8 1.8 8.5 0.1 2.8 2 1 0 3 3 3 0 Microtubule binding Ras PF00071.22 GAK64765.1 - 0.087 12.4 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Ras family DUF87 PF01935.17 GAK64765.1 - 0.11 12.6 0.4 0.85 9.7 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_14 PF13173.6 GAK64765.1 - 0.21 11.6 2.1 1.5 8.9 0.1 2.9 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 GAK64765.1 - 1.1 9.7 4.4 4.7 7.7 4.3 2.0 1 1 0 1 1 1 0 AAA domain FAT PF02259.23 GAK64766.1 - 1.4e-125 419.2 3.1 1.4e-125 419.2 3.1 2.4 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 GAK64766.1 - 4.9e-69 232.9 0.0 9.5e-69 232.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 GAK64766.1 - 5.3e-58 195.5 0.2 4.1e-54 182.8 0.0 4.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 GAK64766.1 - 2.7e-43 146.4 0.3 2.7e-43 146.4 0.3 3.8 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 GAK64766.1 - 2.1e-16 60.0 12.7 0.004 17.5 0.0 11.7 10 2 2 13 13 12 3 HEAT repeats FATC PF02260.20 GAK64766.1 - 5e-12 45.4 0.2 1.2e-11 44.2 0.2 1.7 1 0 0 1 1 1 1 FATC domain UME PF08064.13 GAK64766.1 - 3.3e-08 33.4 4.0 0.096 12.6 0.2 6.3 6 1 1 7 7 7 2 UME (NUC010) domain HEAT PF02985.22 GAK64766.1 - 8.6e-07 28.7 18.7 2.2 8.7 0.1 11.2 13 0 0 13 13 12 2 HEAT repeat Vac14_Fab1_bd PF12755.7 GAK64766.1 - 3.4e-05 24.4 0.0 28 5.4 0.0 5.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region TPR_19 PF14559.6 GAK64766.1 - 0.00019 21.9 0.4 6 7.5 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat CLASP_N PF12348.8 GAK64766.1 - 0.0018 17.9 1.1 35 3.8 0.0 6.8 5 3 3 9 9 9 0 CLASP N terminal Cnd1 PF12717.7 GAK64766.1 - 0.0029 17.7 1.1 3.1 7.8 0.0 4.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 GAK64766.1 - 0.0058 16.6 0.5 7.4 6.5 0.0 4.0 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal VHS PF00790.19 GAK64766.1 - 0.018 14.9 0.1 1.2 9.0 0.0 3.6 4 0 0 4 4 3 0 VHS domain TPR_1 PF00515.28 GAK64766.1 - 0.03 14.2 0.7 22 5.1 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 GAK64766.1 - 0.035 14.6 27.2 7.3 7.2 0.1 10.6 12 1 1 13 13 9 0 HEAT-like repeat Cas_Csy4 PF09618.10 GAK64766.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) TPR_7 PF13176.6 GAK64766.1 - 0.21 11.7 1.1 29 5.0 0.0 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PIN_3 PF13470.6 GAK64766.1 - 0.37 11.6 1.5 3 8.6 0.1 3.1 3 0 0 3 3 2 0 PIN domain Adaptin_N PF01602.20 GAK64766.1 - 0.8 8.2 6.6 5 5.6 0.4 3.9 3 1 1 4 4 4 0 Adaptin N terminal region TPR_2 PF07719.17 GAK64766.1 - 2.2 8.6 10.0 4.9 7.5 0.3 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat DHO_dh PF01180.21 GAK64767.1 - 1.4e-99 333.0 0.0 2e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 GAK64767.1 - 0.00089 18.4 1.3 0.06 12.4 1.3 2.7 2 1 0 2 2 2 2 FMN-dependent dehydrogenase LSM PF01423.22 GAK64768.1 - 5.1e-14 51.7 0.0 6.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sel1 PF08238.12 GAK64769.1 - 2.7e-40 135.9 29.4 7.4e-07 29.6 0.5 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_16 PF13432.6 GAK64769.1 - 0.17 12.6 6.4 28 5.4 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat DPBB_1 PF03330.18 GAK64770.1 - 2.6e-08 34.0 0.4 5.8e-08 32.9 0.4 1.6 1 1 0 1 1 1 1 Lytic transglycolase Glucodextran_B PF09136.10 GAK64770.1 - 0.091 13.1 1.5 0.22 11.9 0.1 2.0 1 1 1 2 2 2 0 Glucodextranase, domain B Connexin43 PF03508.13 GAK64770.1 - 0.8 9.3 4.3 1.4 8.5 4.3 1.4 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) AhpC-TSA PF00578.21 GAK64772.1 - 1.3e-25 89.7 0.0 1.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAK64772.1 - 1.2e-11 44.5 0.0 2.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin CKS PF01111.19 GAK64773.1 - 5.2e-32 109.9 0.2 7.5e-32 109.4 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Sec23_trunk PF04811.15 GAK64774.1 - 1.2e-74 251.0 0.0 2e-74 250.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAK64774.1 - 8.4e-23 80.2 0.5 1.9e-22 79.0 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAK64774.1 - 5.8e-16 59.0 0.0 1.6e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAK64774.1 - 4.8e-15 55.3 9.1 9.4e-15 54.4 9.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAK64774.1 - 6.7e-08 32.3 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 GAK64774.1 - 2.5e-07 30.6 1.1 5.9e-07 29.5 1.1 1.7 1 0 0 1 1 1 1 WW domain Vps36-NZF-N PF16988.5 GAK64774.1 - 0.013 14.9 4.4 0.027 13.9 4.4 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SLATT_4 PF18186.1 GAK64774.1 - 0.11 12.1 0.1 0.55 9.9 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 PWI PF01480.17 GAK64775.1 - 9.9e-08 32.2 1.8 1.2e-07 32.0 0.1 1.9 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 GAK64775.1 - 1.6e-05 24.6 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mpv17_PMP22 PF04117.12 GAK64776.1 - 9e-24 83.5 1.5 1.9e-23 82.5 1.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2723 PF11028.8 GAK64776.1 - 0.041 13.8 0.2 6.9 6.6 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2723) Thymidylate_kin PF02223.17 GAK64777.1 - 9.6e-44 149.3 0.0 1.6e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 GAK64777.1 - 0.032 14.5 2.3 0.077 13.2 0.0 2.3 2 1 0 3 3 3 0 AAA domain PPK2 PF03976.14 GAK64777.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) TFIIF_alpha PF05793.12 GAK64778.1 - 3.6e-08 32.5 54.5 0.00047 18.9 0.0 3.7 3 1 1 4 4 4 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mre11_DNA_bind PF04152.14 GAK64778.1 - 0.18 12.1 3.7 5.1 7.4 0.5 2.8 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain Chitin_synth_2 PF03142.15 GAK64779.1 - 3.2e-238 791.6 0.4 4.3e-238 791.2 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAK64779.1 - 2.9e-129 432.3 0.0 1.1e-112 377.5 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 GAK64779.1 - 1.4e-15 57.0 0.1 5.8e-15 55.0 0.2 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 GAK64779.1 - 3.8e-13 49.4 0.2 9.3e-09 35.3 0.0 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAK64779.1 - 2.6e-12 47.1 1.6 2.6e-12 47.1 1.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK64779.1 - 7.8e-09 35.8 0.0 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAK64779.1 - 0.021 14.7 0.0 6.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 BRCA-2_OB1 PF09103.10 GAK64783.1 - 1.6e-34 118.5 0.0 2.8e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 GAK64783.1 - 1e-08 34.7 0.1 2e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 BRCA2 repeat BRCA-2_helical PF09169.10 GAK64783.1 - 1.5e-07 31.2 0.5 2.3e-06 27.4 1.0 2.1 2 0 0 2 2 2 1 BRCA2, helical CHASE8 PF17152.4 GAK64783.1 - 3 8.2 6.5 2.5 8.4 2.2 2.8 2 0 0 2 2 2 0 Periplasmic sensor domain SIS PF01380.22 GAK64784.1 - 3e-62 208.3 0.2 2.7e-34 117.8 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAK64784.1 - 2.2e-15 57.1 0.0 5.8e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAK64784.1 - 2.1e-11 43.8 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAK64784.1 - 0.00012 21.1 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II YoeB_toxin PF06769.14 GAK64784.1 - 0.18 11.8 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system 2-oxoacid_dh PF00198.23 GAK64785.1 - 2.7e-55 187.3 0.0 8.2e-55 185.8 0.0 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAK64785.1 - 9.4e-19 67.0 0.1 1.9e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAK64785.1 - 2.8e-17 62.8 0.7 1.1e-16 60.8 0.1 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAK64785.1 - 0.026 14.3 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like Helicase_C_2 PF13307.6 GAK64786.1 - 3.9e-56 189.9 0.0 1.1e-55 188.5 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAK64786.1 - 7.7e-47 159.2 0.0 1.2e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 GAK64786.1 - 0.0038 17.2 0.0 2.9 7.9 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit NUDIX-like PF09296.11 GAK64786.1 - 0.026 15.2 0.0 0.077 13.7 0.0 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain DEAD PF00270.29 GAK64786.1 - 0.049 13.4 0.0 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase TPT PF03151.16 GAK64787.1 - 1.9e-21 76.7 17.1 2.4e-21 76.4 17.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Sec61_beta PF03911.16 GAK64787.1 - 1.1 9.3 5.2 32 4.7 0.2 3.5 3 0 0 3 3 3 0 Sec61beta family PXA PF02194.15 GAK64788.1 - 4e-43 147.5 0.0 1.7e-42 145.5 0.0 2.2 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 GAK64788.1 - 1.5e-26 93.2 0.0 5e-26 91.5 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 GAK64788.1 - 2.2e-14 53.4 0.0 8.5e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.19 GAK64788.1 - 5e-07 30.0 0.1 1.5e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain CDH1_2_SANT_HL1 PF18375.1 GAK64788.1 - 0.065 13.9 0.1 0.25 12.0 0.1 2.0 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 CAML PF14963.6 GAK64788.1 - 0.12 12.5 0.4 0.3 11.2 0.4 1.6 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand GAS PF13851.6 GAK64788.1 - 3 7.1 7.7 1.2 8.5 2.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mog1 PF04603.12 GAK64790.1 - 6.7e-40 136.7 0.0 7.9e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Sterol_MT_C PF08498.10 GAK64791.1 - 5.5e-28 97.1 1.6 9.5e-28 96.3 1.6 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 GAK64791.1 - 1.7e-20 73.4 0.0 2.6e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK64791.1 - 3.5e-19 69.2 0.0 7.2e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK64791.1 - 7.6e-17 61.8 0.0 1.6e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAK64791.1 - 1.3e-15 57.4 0.0 1.9e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAK64791.1 - 2.8e-13 50.1 0.0 4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK64791.1 - 1e-12 48.7 0.0 2.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK64791.1 - 4.1e-08 32.9 0.0 6.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 GAK64791.1 - 5.3e-05 22.5 0.0 8.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 GAK64791.1 - 8.6e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAK64791.1 - 0.00079 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 GAK64791.1 - 0.0011 18.6 0.1 0.0018 17.8 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 GAK64791.1 - 0.0014 19.6 0.1 0.044 14.8 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain UPF0020 PF01170.18 GAK64791.1 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 GAK64791.1 - 0.0036 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAK64791.1 - 0.0052 16.4 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 GAK64791.1 - 0.0067 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltr_RsmB-F PF01189.17 GAK64791.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PrmA PF06325.13 GAK64791.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GAK64791.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.20 GAK64791.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DHFR_1 PF00186.19 GAK64792.1 - 5.3e-28 97.7 0.0 1.8e-27 96.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrofolate reductase Cyclin_N PF00134.23 GAK64794.1 - 2.4e-13 49.9 0.0 2.4e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAK64794.1 - 0.00015 21.7 0.4 0.00041 20.3 0.1 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 GAK64794.1 - 0.0015 18.6 0.2 0.67 10.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain DnaJ PF00226.31 GAK64795.1 - 2.2e-17 62.9 0.1 6.5e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain Vps54_N PF10475.9 GAK64795.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Cyclin_N PF00134.23 GAK64796.1 - 6.2e-08 32.4 3.7 6.4e-08 32.4 0.2 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 GAK64796.1 - 0.052 13.9 0.2 0.44 11.0 0.0 2.3 2 1 0 2 2 2 0 Cyclin C-terminal domain ATP-synt_ab PF00006.25 GAK64798.1 - 1.3e-60 204.7 0.0 2.5e-60 203.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAK64798.1 - 3.1e-23 82.1 4.3 3.1e-23 82.1 4.3 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 GAK64798.1 - 0.035 13.4 0.2 0.062 12.6 0.2 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 GAK64798.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GAK64798.1 - 0.091 11.9 0.9 0.18 10.9 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 GAK64798.1 - 0.098 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 GAK64798.1 - 0.21 11.9 0.7 0.85 9.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 GAK64798.1 - 0.53 9.2 1.3 4.1 6.2 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 ERCC4 PF02732.15 GAK64799.1 - 1.4e-20 74.1 0.0 3.1e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain Pmp3 PF01679.17 GAK64800.1 - 4.5e-15 55.6 5.3 7.2e-15 54.9 5.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Glyco_transf_90 PF05686.12 GAK64801.1 - 1.1e-24 87.1 0.0 2.1e-24 86.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 XPG_I PF00867.18 GAK64802.1 - 5.1e-23 81.2 0.0 1.1e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAK64802.1 - 5.3e-23 81.4 0.0 1.2e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 GAK64802.1 - 0.00032 20.2 0.0 0.00065 19.2 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 GAK64802.1 - 0.005 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Siah-Interact_N PF09032.11 GAK64802.1 - 0.71 10.2 2.9 27 5.2 0.2 3.0 2 0 0 2 2 2 0 Siah interacting protein, N terminal LSM PF01423.22 GAK64803.1 - 9.6e-18 63.6 0.9 1.2e-17 63.3 0.9 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 GAK64803.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Redoxin PF08534.10 GAK64804.1 - 8.1e-09 35.3 0.0 9.3e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAK64804.1 - 1.6e-05 24.8 0.0 0.00021 21.2 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family DUF899 PF05988.12 GAK64804.1 - 0.028 14.0 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Adap_comp_sub PF00928.21 GAK64805.1 - 1.7e-82 276.8 0.0 2.2e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RNase_PH PF01138.21 GAK64805.1 - 3.5e-24 85.8 0.0 7.6e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Clat_adaptor_s PF01217.20 GAK64805.1 - 0.0018 18.2 0.7 0.0032 17.4 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAK64805.1 - 0.048 13.1 0.2 0.081 12.4 0.2 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Tim54 PF11711.8 GAK64806.1 - 7e-48 163.3 0.3 7e-48 163.3 0.3 3.0 1 1 1 2 2 2 1 Inner membrane protein import complex subunit Tim54 HNOBA PF07701.14 GAK64806.1 - 0.13 11.6 2.8 0.23 10.8 2.8 1.3 1 0 0 1 1 1 0 Heme NO binding associated Adaptin_N PF01602.20 GAK64807.1 - 6.8e-105 351.6 0.0 5.7e-93 312.2 0.0 2.2 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GAK64807.1 - 3.5e-12 46.7 0.0 5.2e-09 36.4 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAK64807.1 - 2.8e-08 34.0 4.0 0.0028 18.0 0.2 3.8 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 GAK64807.1 - 8.5e-06 25.6 1.7 5.7 7.5 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat AP3D1 PF06375.11 GAK64807.1 - 0.00036 20.8 0.5 0.00071 19.9 0.5 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 RTP1_C1 PF10363.9 GAK64807.1 - 0.0085 16.3 0.3 1.4 9.1 0.0 3.2 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 GAK64807.1 - 0.12 12.5 0.3 21 5.2 0.0 3.2 2 1 0 2 2 2 0 V-ATPase subunit H DUF150 PF02576.17 GAK64807.1 - 0.15 12.5 0.0 22 5.6 0.0 2.6 2 0 0 2 2 2 0 RimP N-terminal domain DUF3384 PF11864.8 GAK64807.1 - 0.18 10.6 0.1 0.46 9.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3384) DBD_HTH PF18430.1 GAK64807.1 - 0.21 11.4 1.5 1.6 8.5 0.0 2.6 3 0 0 3 3 3 0 Putative DNA-binding domain ABC2_membrane PF01061.24 GAK64808.1 - 8.9e-30 103.7 19.0 8.9e-30 103.7 19.0 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAK64808.1 - 2e-26 93.2 0.0 3.5e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAK64808.1 - 2.1e-06 27.8 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GAK64808.1 - 1.6e-05 24.2 8.5 2.5e-05 23.6 2.7 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 GAK64808.1 - 5.8e-05 22.7 0.3 0.00024 20.8 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAK64808.1 - 0.0013 18.7 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 GAK64808.1 - 0.0018 17.9 0.4 0.18 11.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAK64808.1 - 0.0059 17.0 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 GAK64808.1 - 0.037 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAK64808.1 - 0.046 14.0 0.0 0.092 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAK64808.1 - 0.051 13.5 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 GAK64808.1 - 0.057 14.0 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAK64808.1 - 0.088 13.3 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAK64808.1 - 0.09 13.0 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAK64808.1 - 0.13 12.4 0.1 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAK64808.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Aminotran_5 PF00266.19 GAK64809.1 - 5.1e-28 98.1 0.0 7.9e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V TPR_12 PF13424.6 GAK64810.1 - 7.4e-06 26.2 3.2 2.7e-05 24.3 3.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAK64810.1 - 0.11 12.8 0.1 0.71 10.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat UAA PF08449.11 GAK64811.1 - 2.8e-45 154.8 4.0 8.1e-45 153.3 4.0 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAK64811.1 - 3.9e-10 40.0 20.8 5.8e-08 33.0 4.4 4.2 4 1 0 4 4 4 2 EamA-like transporter family PUNUT PF16913.5 GAK64811.1 - 1.2e-05 24.7 5.1 2e-05 24.0 5.1 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 GAK64811.1 - 0.00011 21.6 8.4 0.00041 19.8 1.2 2.8 2 1 1 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 GAK64811.1 - 0.00083 18.6 2.5 0.15 11.2 0.2 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 GAK64811.1 - 0.0057 15.6 6.0 0.66 8.9 0.2 2.5 2 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 GAK64811.1 - 0.66 10.0 4.2 9.7 6.3 0.6 2.7 2 0 0 2 2 2 0 Putative transmembrane family 234 PhyH PF05721.13 GAK64812.1 - 4.2e-05 23.9 0.0 7.8e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Lysine_decarbox PF03641.14 GAK64813.1 - 1.8e-31 109.0 0.1 3.3e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase ABC_tran PF00005.27 GAK64813.1 - 1.3e-14 54.9 0.0 3e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 ABC transporter LDcluster4 PF18306.1 GAK64813.1 - 6.9e-11 42.0 1.7 1.7e-10 40.7 1.7 1.6 1 1 0 1 1 1 1 SLOG cluster4 family AAA_21 PF13304.6 GAK64813.1 - 3.3e-09 37.0 4.1 0.00037 20.4 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAK64813.1 - 0.00031 20.4 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAK64813.1 - 0.00083 19.0 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK64813.1 - 0.0036 17.7 0.1 0.0066 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 GAK64813.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAK64813.1 - 0.025 14.7 0.0 0.07 13.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK64813.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 GAK64813.1 - 0.041 13.3 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAK64813.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 GAK64813.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 GAK64813.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family L51_S25_CI-B8 PF05047.16 GAK64815.1 - 0.00045 20.1 0.0 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SH3_1 PF00018.28 GAK64816.1 - 2.3e-12 46.3 0.1 4.2e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK64816.1 - 5.8e-10 38.9 0.0 1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAK64816.1 - 7.1e-08 32.0 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 GAK64816.1 - 0.0032 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Bac_rhodopsin PF01036.18 GAK64816.1 - 0.0093 15.6 9.9 0.013 15.1 9.9 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Kinesin PF00225.23 GAK64817.1 - 1.4e-100 336.5 0.5 7.5e-55 186.2 0.0 3.3 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 GAK64817.1 - 1e-24 87.2 0.0 3.3e-24 85.5 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DUF2353 PF09789.9 GAK64817.1 - 0.00085 18.8 4.1 0.00085 18.8 4.1 7.6 4 2 3 7 7 7 4 Uncharacterized coiled-coil protein (DUF2353) SMN PF06003.12 GAK64817.1 - 2.1 7.5 5.9 5 6.3 1.8 3.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Filament PF00038.21 GAK64817.1 - 4.7 6.7 130.5 0.017 14.7 4.3 9.1 5 2 3 8 8 8 0 Intermediate filament protein TLV_coat PF00429.19 GAK64818.1 - 0.014 14.1 0.2 0.016 13.9 0.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) FAM176 PF14851.6 GAK64818.1 - 0.029 14.0 0.5 0.036 13.7 0.5 1.3 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 GAK64818.1 - 0.13 10.3 1.2 0.13 10.3 1.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_60s PF00428.19 GAK64818.1 - 5.4 7.7 16.5 1.5 9.4 12.9 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ECH_1 PF00378.20 GAK64819.1 - 2.7e-42 144.8 0.0 3.4e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK64819.1 - 6.9e-19 68.5 0.3 1.5e-18 67.4 0.3 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CBFD_NFYB_HMF PF00808.23 GAK64820.1 - 5.2e-19 68.3 0.2 5.2e-19 68.3 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2458 PF10454.9 GAK64820.1 - 0.0071 16.0 0.4 0.0099 15.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Histone PF00125.24 GAK64820.1 - 0.018 15.4 1.6 0.092 13.1 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 YolD PF08863.10 GAK64820.1 - 0.037 14.1 2.1 0.1 12.7 1.1 1.9 2 0 0 2 2 2 0 YolD-like protein DAHP_synth_1 PF00793.20 GAK64821.1 - 2.8e-98 328.2 0.0 3.4e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family zf-RING_2 PF13639.6 GAK64822.1 - 3.3e-12 46.5 5.7 5.4e-12 45.9 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAK64822.1 - 5.9e-09 35.5 3.1 1e-08 34.7 3.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAK64822.1 - 3.3e-07 30.0 5.9 5.3e-07 29.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK64822.1 - 8.5e-07 28.7 7.5 1.4e-06 28.1 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK64822.1 - 1.2e-06 28.4 7.5 1.8e-06 27.8 7.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAK64822.1 - 1.2e-05 25.2 2.9 2.3e-05 24.3 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAK64822.1 - 3e-05 24.2 5.3 6.3e-05 23.2 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAK64822.1 - 6.3e-05 22.8 6.9 0.0001 22.1 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK64822.1 - 0.001 18.9 7.0 0.0017 18.1 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GAK64822.1 - 0.071 12.8 4.7 0.13 11.9 4.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAK64822.1 - 0.44 10.4 4.2 0.79 9.6 4.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 GAK64822.1 - 0.71 10.0 3.2 1.5 8.9 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 GAK64822.1 - 0.76 9.8 4.9 1.8 8.5 4.9 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 GAK64822.1 - 6.5 6.9 5.1 11 6.2 5.1 1.4 1 0 0 1 1 1 0 Zinc-finger Peroxin-13_N PF04088.13 GAK64823.1 - 6.9e-48 162.6 0.1 6.9e-48 162.6 0.1 1.6 2 0 0 2 2 2 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 GAK64823.1 - 1.2e-12 47.2 0.0 2.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK64823.1 - 1.4e-11 44.0 0.7 3.2e-11 42.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAK64823.1 - 9.5e-11 41.2 0.0 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 GAK64824.1 - 1.6e-51 171.1 26.1 7.9e-11 42.3 0.2 8.0 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64824.1 - 2.5e-14 53.3 1.2 1.3e-05 25.4 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK64824.1 - 5.3e-12 45.2 5.9 0.00017 20.4 0.0 5.5 2 1 2 5 5 5 2 Nucleoporin Nup120/160 LisH_TPL PF17814.1 GAK64824.1 - 0.0014 18.2 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 GAK64824.1 - 0.0034 17.3 0.1 0.0068 16.3 0.1 1.5 1 0 0 1 1 1 1 LisH DUF2600 PF10776.9 GAK64824.1 - 0.18 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) IF-2B PF01008.17 GAK64825.1 - 3.1e-57 193.9 0.0 3.8e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DEAD PF00270.29 GAK64826.1 - 9.1e-49 165.6 0.0 7e-48 162.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK64826.1 - 1.6e-30 105.7 0.0 8.1e-29 100.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 GAK64826.1 - 0.0073 15.1 0.5 0.88 8.3 0.0 3.5 3 1 1 4 4 4 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Aminotran_3 PF00202.21 GAK64827.1 - 1.5e-121 405.9 0.0 1.9e-121 405.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAK64827.1 - 0.0018 17.5 0.0 0.0039 16.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAK64827.1 - 0.023 14.0 0.0 0.13 11.5 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase DUF2007 PF09413.10 GAK64827.1 - 0.028 14.6 0.0 6.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein DUF3128 PF11326.8 GAK64828.1 - 1.8e-23 82.7 1.5 3.1e-23 82.0 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Torus PF16131.5 GAK64828.1 - 0.11 13.2 0.5 0.21 12.3 0.5 1.5 1 0 0 1 1 1 0 Torus domain zf-H2C2_2 PF13465.6 GAK64829.1 - 4.3e-21 74.3 19.6 9.1e-06 25.9 0.1 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 GAK64829.1 - 1.3e-19 69.5 28.0 7.7e-06 26.1 2.1 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK64829.1 - 9.1e-07 29.2 33.3 0.026 15.3 1.4 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAK64829.1 - 0.002 18.3 3.2 1.3 9.4 0.0 3.1 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 GAK64829.1 - 0.0098 16.6 11.3 0.0098 16.6 11.3 3.3 4 0 0 4 4 2 1 Protein of unknown function (FYDLN_acid) FOXP-CC PF16159.5 GAK64829.1 - 0.039 14.6 3.6 30 5.3 0.2 3.8 2 1 2 4 4 4 0 FOXP coiled-coil domain RXT2_N PF08595.11 GAK64829.1 - 0.039 14.0 2.6 0.094 12.7 2.6 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal zf-met PF12874.7 GAK64829.1 - 0.053 13.9 9.9 0.61 10.6 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Nop14 PF04147.12 GAK64829.1 - 0.094 10.9 16.4 0.14 10.3 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAK64829.1 - 0.15 10.4 13.6 0.28 9.4 13.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GAK64829.1 - 0.17 10.3 10.9 0.28 9.6 10.9 1.2 1 0 0 1 1 1 0 Mpp10 protein zf-C2H2_6 PF13912.6 GAK64829.1 - 0.33 11.0 15.7 0.14 12.2 0.5 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger DNA_pol_phi PF04931.13 GAK64829.1 - 0.44 8.6 21.5 0.63 8.1 21.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 GAK64829.1 - 0.59 10.3 21.1 0.058 13.6 12.3 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 zf-TRAF PF02176.18 GAK64829.1 - 2.1 9.1 11.1 0.062 14.0 1.2 2.8 2 1 1 3 3 3 0 TRAF-type zinc finger FAM176 PF14851.6 GAK64829.1 - 4.9 6.8 8.1 15 5.3 8.1 1.8 1 0 0 1 1 1 0 FAM176 family zf-C2H2_11 PF16622.5 GAK64829.1 - 7.8 6.4 16.4 2.9 7.7 1.4 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type COPI_C PF06957.11 GAK64829.1 - 8.3 5.0 8.3 13 4.4 8.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOA36 PF06524.12 GAK64829.1 - 9.2 5.5 27.8 6.5 6.0 26.1 1.4 1 1 0 1 1 1 0 NOA36 protein Utp14 PF04615.13 GAK64829.1 - 9.6 4.6 18.3 0.54 8.8 10.4 2.0 2 0 0 2 2 2 0 Utp14 protein Astro_capsid_p PF12226.8 GAK64829.1 - 9.6 5.2 16.2 18 4.4 16.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HGTP_anticodon PF03129.20 GAK64832.1 - 1.3e-20 73.3 0.1 4.3e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAK64832.1 - 2e-09 37.7 0.1 5.4e-09 36.3 0.1 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1465 PF07323.12 GAK64833.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) zf-C2H2 PF00096.26 GAK64834.1 - 3.7e-15 55.4 23.6 8.1e-05 22.9 1.8 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK64834.1 - 1.4e-13 50.6 23.0 1.2e-06 28.7 0.2 5.1 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAK64834.1 - 0.00037 21.1 22.7 0.46 11.4 0.5 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAK64834.1 - 0.0069 16.7 11.6 0.017 15.4 6.7 3.5 2 1 2 4 4 4 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAK64834.1 - 0.041 14.5 8.7 0.99 10.1 0.0 3.5 4 1 0 4 4 4 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 GAK64834.1 - 1.6 8.9 4.3 17 5.5 0.1 2.9 2 1 1 3 3 3 0 Aberrant zinc-finger zf-TRAF PF02176.18 GAK64834.1 - 6.2 7.6 10.1 0.55 11.0 1.7 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger NUDIX PF00293.28 GAK64835.1 - 6.6e-17 61.8 0.0 1.6e-15 57.3 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain Sel1 PF08238.12 GAK64836.1 - 1.2e-07 32.1 17.5 1.2e-06 29.0 0.2 5.3 5 0 0 5 5 5 1 Sel1 repeat TPR_2 PF07719.17 GAK64836.1 - 0.00061 19.7 0.4 0.029 14.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAK64836.1 - 0.048 13.5 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK64836.1 - 0.049 14.3 4.2 2.6 8.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK64836.1 - 6.3 7.9 13.3 21 6.3 0.3 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_10 PF05176.14 GAK64837.1 - 8.1e-54 182.6 0.0 1e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein GFO_IDH_MocA PF01408.22 GAK64839.1 - 3.9e-24 85.8 0.6 6.6e-24 85.0 0.6 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAK64839.1 - 5.2e-05 23.9 1.0 8.1e-05 23.3 1.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 GAK64839.1 - 0.0041 17.5 0.1 0.0084 16.5 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Rossmann-like PF10727.9 GAK64839.1 - 0.018 14.9 0.3 0.032 14.1 0.3 1.4 1 0 0 1 1 1 0 Rossmann-like domain F420_oxidored PF03807.17 GAK64839.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SMP PF04927.12 GAK64839.1 - 0.14 12.6 0.4 0.14 12.6 0.4 2.0 2 0 0 2 2 2 0 Seed maturation protein Redoxin PF08534.10 GAK64840.1 - 2.5e-29 101.9 0.1 3.1e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAK64840.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family RRM_1 PF00076.22 GAK64841.1 - 5.5e-07 29.3 0.0 6.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAK64841.1 - 2.5e-06 27.2 0.0 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 GAK64841.1 - 0.006 16.6 0.0 0.0077 16.3 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 GAK64841.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAK64841.1 - 0.074 13.1 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 Fip1 PF05182.13 GAK64842.1 - 6.6e-19 67.1 2.5 1.5e-18 66.0 1.5 2.1 2 0 0 2 2 2 1 Fip1 motif PAS_9 PF13426.7 GAK64843.1 - 6.6e-23 80.9 0.0 9.4e-14 51.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 GAK64843.1 - 5.1e-16 58.7 0.0 2.4e-07 30.9 0.0 4.0 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 GAK64843.1 - 6.7e-16 58.3 0.0 4.5e-10 39.5 0.0 4.2 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 GAK64843.1 - 7.9e-08 32.5 0.0 0.00018 21.7 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 GAK64843.1 - 1.6e-05 24.8 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 GAK64843.1 - 0.0076 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain SMC_N PF02463.19 GAK64846.1 - 2.9e-73 246.0 2.2 5.9e-72 241.7 2.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAK64846.1 - 2.6e-22 79.3 0.0 7.2e-22 77.9 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAK64846.1 - 2.9e-11 43.7 6.1 3.6e-05 23.7 0.6 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAK64846.1 - 0.00026 21.6 23.2 0.00026 21.6 23.2 6.4 4 2 1 5 5 5 1 AAA domain AAA_29 PF13555.6 GAK64846.1 - 0.0008 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAK64846.1 - 0.0026 18.0 0.4 27 5.0 0.0 4.2 3 0 0 3 3 3 0 AAA domain DivIVA PF05103.13 GAK64846.1 - 0.0048 17.0 4.9 0.0048 17.0 4.9 7.1 4 3 3 7 7 7 2 DivIVA protein KR PF08659.10 GAK64847.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 KR domain Pkinase PF00069.25 GAK64848.1 - 3.1e-62 210.3 0.0 1.2e-61 208.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64848.1 - 9.9e-29 100.4 0.0 8.7e-28 97.3 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAK64848.1 - 0.00063 18.8 0.1 0.00091 18.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAK64848.1 - 0.0038 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Exo_endo_phos PF03372.23 GAK64849.1 - 1.3e-22 80.4 0.1 6.1e-22 78.3 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 GAK64849.1 - 2.3e-08 33.7 6.2 0.00063 19.5 0.6 2.4 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAK64849.1 - 3.8e-08 33.5 6.4 0.0012 19.2 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) HSP90 PF00183.18 GAK64850.1 - 6.4e-224 744.6 23.3 8.3e-224 744.3 23.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAK64850.1 - 4.7e-15 56.1 0.1 9.3e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAK64850.1 - 8.8e-11 41.8 0.1 2.6e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 GAK64850.1 - 0.06 13.3 0.1 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Glyco_hydro_79C PF16862.5 GAK64851.1 - 3.6e-14 53.5 0.0 9.1e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Cellulase PF00150.18 GAK64851.1 - 9.6e-05 21.9 0.1 0.00014 21.4 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.13 GAK64852.1 - 5.3e-36 124.5 0.0 6.7e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAK64852.1 - 6.8e-08 32.2 0.0 3.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAK64852.1 - 0.00011 21.8 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAK64852.1 - 0.0032 17.2 0.1 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 GAK64852.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 GAK64852.1 - 0.0095 15.8 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 GAK64852.1 - 0.013 14.2 0.1 0.023 13.3 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 GAK64852.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WD40 PF00400.32 GAK64853.1 - 0.86 10.6 2.5 2.6 9.1 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat adh_short PF00106.25 GAK64854.1 - 1.7e-33 115.7 0.2 2.2e-33 115.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK64854.1 - 8.5e-22 77.8 0.1 1.3e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK64854.1 - 2.3e-09 37.4 0.3 4.9e-09 36.3 0.3 1.4 1 1 0 1 1 1 1 KR domain Erf4 PF10256.9 GAK64855.1 - 5.1e-10 39.5 0.0 9.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.6 GAK64855.1 - 0.0012 19.5 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Esterase_phd PF10503.9 GAK64856.1 - 8.8e-05 22.1 0.1 0.00015 21.3 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.11 GAK64856.1 - 0.0035 17.3 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAK64856.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Putative_PNPOx PF01243.20 GAK64857.1 - 0.00043 20.4 0.1 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Zn_clus PF00172.18 GAK64858.1 - 0.0014 18.7 7.3 0.0032 17.6 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 GAK64859.1 - 0.00011 21.9 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 RTA1 like protein FMN_red PF03358.15 GAK64861.1 - 1.8e-23 83.0 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAK64861.1 - 0.0052 16.5 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold adh_short PF00106.25 GAK64862.1 - 8.2e-34 116.8 0.3 1.2e-33 116.2 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK64862.1 - 1.5e-16 60.6 0.8 2.6e-16 59.9 0.8 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK64862.1 - 7.3e-11 42.3 2.2 1.1e-09 38.4 2.2 2.2 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAK64862.1 - 0.0085 15.3 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAK64862.1 - 0.033 14.1 0.1 0.098 12.5 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H-binding Abhydrolase_3 PF07859.13 GAK64863.1 - 8.1e-21 74.9 0.5 4.1e-19 69.3 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold NicO PF03824.16 GAK64864.1 - 2.8e-35 122.0 6.7 3.5e-34 118.4 0.4 3.5 2 2 0 2 2 2 1 High-affinity nickel-transport protein Phage_holin_2_4 PF16082.5 GAK64864.1 - 0.035 13.8 0.5 0.035 13.8 0.5 2.4 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like EphA2_TM PF14575.6 GAK64864.1 - 2.8 8.9 5.2 18 6.3 0.0 4.0 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain 4HBT_2 PF13279.6 GAK64865.1 - 2.9e-06 27.8 0.0 4.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily HgmA PF04209.13 GAK64867.1 - 8.3e-192 637.6 0.6 9.5e-192 637.4 0.6 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CompInhib_SCIN PF11546.8 GAK64868.1 - 0.031 14.3 0.3 0.16 12.0 0.0 2.0 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN Sterile PF03015.19 GAK64868.1 - 0.089 13.0 0.0 9.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Male sterility protein Fungal_trans PF04082.18 GAK64869.1 - 5.4e-26 91.2 0.1 8.8e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK64869.1 - 1.7e-07 31.2 11.1 3.4e-07 30.3 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAK64869.1 - 0.1 11.4 2.6 0.27 10.0 2.6 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.22 GAK64870.1 - 1.3e-71 241.8 0.0 1.5e-71 241.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1409 PF07197.12 GAK64870.1 - 0.14 12.1 0.9 10 6.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) FAA_hydrolase PF01557.18 GAK64871.1 - 1.4e-49 168.8 0.0 2.1e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAK64871.1 - 7.1e-22 77.6 0.0 1.8e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal PGAP1 PF07819.13 GAK64872.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Cyclin PF08613.11 GAK64873.1 - 5.6e-31 108.1 0.0 5.6e-31 108.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAK64873.1 - 0.00017 21.3 0.2 0.00026 20.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain FeS_assembly_P PF01883.19 GAK64874.1 - 1e-11 44.8 0.0 2.5e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein NOA36 PF06524.12 GAK64874.1 - 0.27 10.5 2.8 0.45 9.8 2.8 1.2 1 0 0 1 1 1 0 NOA36 protein Med19 PF10278.9 GAK64875.1 - 0.011 15.7 0.2 0.023 14.7 0.2 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nucleoporin_FG2 PF15967.5 GAK64876.1 - 2.1e-07 29.9 0.6 2.1e-07 29.9 0.6 4.0 2 1 2 4 4 4 1 Nucleoporin FG repeated region Nucleoporin_FG PF13634.6 GAK64876.1 - 2.4e-05 25.1 31.3 2.4e-05 25.1 31.3 3.9 1 1 2 3 3 3 1 Nucleoporin FG repeat region Seryl_tRNA_N PF02403.22 GAK64876.1 - 0.017 15.3 3.3 0.97 9.7 0.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 GAK64876.1 - 0.036 14.4 0.3 18 5.7 0.0 3.1 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.6 GAK64876.1 - 0.049 13.0 1.7 0.14 11.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) COG2 PF06148.11 GAK64876.1 - 0.12 12.4 0.5 0.62 10.1 0.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mating_N PF12731.7 GAK64876.1 - 0.17 12.0 3.1 0.27 11.4 0.1 2.6 2 2 0 2 2 2 0 Mating-type protein beta 1 Filament PF00038.21 GAK64876.1 - 0.22 11.1 4.8 1.7 8.1 0.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 GAK64876.1 - 0.9 8.4 5.8 7.6 5.3 0.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein SUIM_assoc PF16619.5 GAK64876.1 - 1.2 9.3 25.5 0.19 11.8 0.8 4.5 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 MDM10 PF12519.8 GAK64877.1 - 5.1e-93 312.5 0.1 3.8e-46 157.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 GAK64877.1 - 0.017 14.6 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic porin Ank_2 PF12796.7 GAK64878.1 - 6.4e-12 45.9 0.0 1.3e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK64878.1 - 2.9e-11 43.6 0.4 7e-08 32.9 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAK64878.1 - 2.8e-10 40.2 0.2 3.7e-08 33.5 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAK64878.1 - 7.2e-08 32.5 0.1 1.3e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 GAK64878.1 - 2.7e-07 30.4 0.0 0.00033 20.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Methyltransf_25 PF13649.6 GAK64878.1 - 0.017 15.8 0.0 0.061 14.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain 4HBT_3 PF13622.6 GAK64879.1 - 2.4e-19 70.6 0.2 4.1e-19 69.8 0.2 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily NTF2 PF02136.20 GAK64880.1 - 5.4e-28 98.0 0.7 1.2e-27 96.8 0.5 1.7 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAK64880.1 - 2.3e-05 24.1 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 GAK64880.1 - 0.00026 20.3 0.4 0.00039 19.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) RHD3 PF05879.12 GAK64881.1 - 1.2e-246 820.5 0.4 1.6e-246 820.1 0.4 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 GAK64881.1 - 1.5e-06 27.7 0.2 4.9e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 GAK64881.1 - 5e-05 23.3 0.5 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAK64881.1 - 6.8e-05 23.0 0.0 0.00029 20.9 0.0 2.1 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 GAK64881.1 - 0.0003 21.1 0.3 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain PTS_IIA PF02255.16 GAK64881.1 - 0.071 13.2 1.4 0.2 11.7 1.4 1.8 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Pyr_redox_2 PF07992.14 GAK64882.1 - 9.3e-36 123.5 0.0 3.5e-32 111.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK64882.1 - 6.6e-10 39.4 0.1 4.2e-09 36.8 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HSP20 PF00011.21 GAK64883.1 - 0.0046 17.1 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family MRP-S33 PF08293.11 GAK64884.1 - 1.5e-28 98.8 0.1 1.8e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Peptidase_C14 PF00656.22 GAK64885.1 - 6.7e-60 203.1 0.2 8.7e-60 202.7 0.2 1.0 1 0 0 1 1 1 1 Caspase domain YflT PF11181.8 GAK64885.1 - 0.2 12.1 0.5 0.48 11.0 0.1 1.8 2 0 0 2 2 2 0 Heat induced stress protein YflT MBOAT PF03062.19 GAK64886.1 - 9.5e-52 176.5 4.1 9.5e-52 176.5 4.1 2.0 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family GRIM-19 PF06212.12 GAK64886.1 - 0.15 12.0 0.0 0.5 10.3 0.0 1.9 1 0 0 1 1 1 0 GRIM-19 protein FA_hydroxylase PF04116.13 GAK64887.1 - 8.1e-21 74.8 12.4 8.1e-21 74.8 12.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2013 PF09431.10 GAK64888.1 - 1.7e-53 180.5 0.3 2.6e-53 179.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Sec7_N PF12783.7 GAK64888.1 - 0.52 10.2 3.1 19 5.1 0.4 3.0 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Methyltransf_3 PF01596.17 GAK64889.1 - 3.2e-46 157.2 0.4 4.2e-46 156.8 0.4 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAK64889.1 - 1.3e-11 45.4 0.0 3.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAK64889.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 GAK64889.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 GAK64889.1 - 0.0041 17.8 0.1 0.0087 16.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 GAK64889.1 - 0.02 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase P22_CoatProtein PF11651.8 GAK64889.1 - 0.038 12.6 0.2 0.08 11.5 0.0 1.5 2 0 0 2 2 2 0 P22 coat protein - gene protein 5 TBCC PF07986.12 GAK64890.1 - 9.8e-12 44.7 3.7 1.6e-11 44.0 3.7 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 GAK64890.1 - 0.0045 17.4 0.0 0.0093 16.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Chorismate_synt PF01264.21 GAK64891.1 - 1.2e-137 458.1 0.2 1.4e-137 457.8 0.2 1.1 1 0 0 1 1 1 1 Chorismate synthase EthD PF07110.11 GAK64892.1 - 4e-06 27.9 0.4 0.013 16.6 0.0 2.7 2 1 0 2 2 2 2 EthD domain Coatomer_WDAD PF04053.14 GAK64893.1 - 2.1e-151 505.0 0.0 7.6e-151 503.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAK64893.1 - 3.8e-40 135.1 8.2 1.3e-07 32.1 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64893.1 - 8.6e-12 45.2 0.1 0.0023 18.2 0.0 6.2 4 1 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK64893.1 - 0.11 11.1 1.6 1.1 7.8 0.1 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 GAK64893.1 - 0.12 12.6 0.1 17 5.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MgtE_N PF03448.17 GAK64893.1 - 0.43 11.2 2.4 0.86 10.2 1.5 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain TPR_4 PF07721.14 GAK64893.1 - 0.59 10.9 4.5 2.7 8.9 1.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 GAK64894.1 - 1.1e-12 48.0 0.5 2e-12 47.1 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAK64894.1 - 1.4e-08 34.9 0.3 2.9e-08 33.8 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vps5 PF09325.10 GAK64895.1 - 2.6e-14 53.4 6.0 3.8e-14 52.8 6.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like 5_nucleotid PF05761.14 GAK64895.1 - 0.1 11.5 2.2 0.15 11.0 2.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family SWIB PF02201.18 GAK64896.1 - 1.4e-27 95.3 0.0 2.3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 GAK64896.1 - 4.3e-07 29.8 0.1 1.5e-05 24.8 0.1 2.8 2 1 0 2 2 2 1 DEK C terminal domain ORC6 PF05460.13 GAK64896.1 - 0.0051 16.1 3.9 0.0059 15.9 3.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Bindin PF02084.15 GAK64896.1 - 0.13 12.5 3.5 0.18 12.0 3.5 1.1 1 0 0 1 1 1 0 Bindin SRP-alpha_N PF04086.13 GAK64896.1 - 0.53 10.1 4.9 0.73 9.7 4.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RNase_T PF00929.24 GAK64897.1 - 6.8e-17 62.5 0.0 9.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Chrome_Resist PF09828.9 GAK64897.1 - 0.095 13.1 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromate resistance exported protein 2-Hacid_dh_C PF02826.19 GAK64898.1 - 5e-53 179.1 0.0 8.1e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAK64898.1 - 5.7e-14 51.9 0.0 7.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 GAK64898.1 - 0.016 15.8 0.0 0.045 14.3 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M19 PF01244.21 GAK64898.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) GFO_IDH_MocA PF01408.22 GAK64898.1 - 0.082 13.7 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pectate_lyase_3 PF12708.7 GAK64899.1 - 2e-97 325.2 4.4 7.1e-81 271.1 2.1 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAK64899.1 - 5.9e-08 32.3 1.3 0.0058 16.3 0.5 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PP2C PF00481.21 GAK64900.1 - 4.4e-64 216.6 0.2 4.6e-51 173.9 0.2 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C HMG_box PF00505.19 GAK64901.1 - 2.5e-21 75.9 16.0 4.3e-11 43.1 4.4 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAK64901.1 - 1.7e-17 63.8 12.2 1.2e-08 35.4 4.0 2.6 2 0 0 2 2 2 2 HMG-box domain Methyltransf_16 PF10294.9 GAK64901.1 - 6.4e-17 61.8 0.1 1e-11 44.9 0.0 2.3 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 GAK64901.1 - 0.014 16.1 0.0 0.15 12.8 0.0 2.5 1 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 GAK64901.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain YABBY PF04690.13 GAK64901.1 - 5.3 7.6 14.1 0.063 13.8 5.1 2.4 2 1 1 3 3 3 0 YABBY protein CRAL_TRIO PF00650.20 GAK64903.1 - 3e-36 124.5 0.1 4.5e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAK64903.1 - 1.2e-09 38.2 0.2 4.2e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Acetyltransf_1 PF00583.25 GAK64904.1 - 4.1e-14 52.8 0.0 4.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAK64904.1 - 7.2e-10 38.9 0.1 8.2e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK64904.1 - 2.4e-07 31.1 0.1 3.1e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK64904.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAK64904.1 - 0.00029 20.9 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAK64904.1 - 0.14 11.6 0.2 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 Putative acetyl-transferase GrpB PF04229.14 GAK64905.1 - 0.084 13.1 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 GrpB protein RNase_H PF00075.24 GAK64906.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 RNase H DUF5102 PF17104.5 GAK64907.1 - 2.8e-54 185.1 3.5 2.8e-54 185.1 3.5 2.9 1 1 0 3 3 3 1 Domain of unknown function (DUF5102) FEZ PF07763.13 GAK64907.1 - 0.0011 18.7 0.3 0.041 13.6 0.2 2.4 2 0 0 2 2 2 1 FEZ-like protein Prenyltransf PF01255.19 GAK64908.1 - 1e-70 237.8 0.0 1.2e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_S26 PF10502.9 GAK64909.1 - 2.2e-06 27.5 0.0 0.00075 19.3 0.0 2.4 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAK64909.1 - 4.2e-05 23.4 0.0 0.00024 21.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like RhoGEF PF00621.20 GAK64910.1 - 9.2e-24 84.7 0.1 3.6e-11 43.6 0.0 2.7 3 0 0 3 3 3 2 RhoGEF domain DPBB_1 PF03330.18 GAK64912.1 - 0.012 15.9 0.1 0.029 14.6 0.0 1.8 2 0 0 2 2 2 0 Lytic transglycolase SOG2 PF10428.9 GAK64913.1 - 8.7 5.4 10.9 9.7 5.3 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CAP_GLY PF01302.25 GAK64914.1 - 1.5e-20 73.0 0.1 2.4e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 GAK64914.1 - 1.6e-13 50.6 9.8 4.3e-06 27.0 0.4 4.1 2 2 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAK64914.1 - 3.4e-10 39.5 10.5 1.3e-05 24.9 1.2 4.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 GAK64914.1 - 3.6e-08 33.1 0.0 5.4e-05 22.8 0.0 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 GAK64914.1 - 0.0022 18.3 6.0 78 4.4 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 GAK64914.1 - 0.33 11.1 8.4 13 6.1 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeat STIMATE PF12400.8 GAK64917.1 - 2.1e-41 141.3 0.2 4.1e-41 140.4 0.2 1.5 1 0 0 1 1 1 1 STIMATE family ExoD PF06055.12 GAK64917.1 - 0.023 14.1 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD GN3L_Grn1 PF08701.11 GAK64918.1 - 1.9e-24 85.6 16.6 1.9e-24 85.6 16.6 4.6 5 0 0 5 5 5 1 GNL3L/Grn1 putative GTPase CENP-B_dimeris PF09026.10 GAK64918.1 - 0.00099 19.5 1.8 0.00099 19.5 1.8 6.1 4 1 1 5 5 5 1 Centromere protein B dimerisation domain Nop14 PF04147.12 GAK64918.1 - 0.0065 14.7 47.2 0.018 13.3 2.6 3.2 3 0 0 3 3 3 2 Nop14-like family DUF3246 PF11596.8 GAK64918.1 - 6 6.2 8.3 12 5.2 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DNA_pol_phi PF04931.13 GAK64918.1 - 8.9 4.3 65.1 0.0082 14.3 23.2 3.2 3 0 0 3 3 3 0 DNA polymerase phi RRN3 PF05327.11 GAK64919.1 - 2.1e-183 610.9 0.0 2.1e-183 610.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 GAK64919.1 - 0.3 10.7 10.0 0.96 9.0 0.8 2.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting ORC6 PF05460.13 GAK64919.1 - 3.3 6.9 11.4 9.7 5.3 7.1 2.4 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Thioredoxin PF00085.20 GAK64920.1 - 1.9e-23 82.4 0.3 2.3e-23 82.1 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAK64920.1 - 3.7e-08 33.8 0.4 3e-07 30.9 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAK64920.1 - 1.2e-07 32.0 0.1 3.9e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAK64920.1 - 2.3e-05 24.5 0.1 3.4e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GAK64920.1 - 4.1e-05 23.5 0.0 4.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 GAK64920.1 - 0.00024 21.1 0.1 0.00043 20.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 GAK64920.1 - 0.0012 18.2 0.1 0.0015 17.9 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 GAK64920.1 - 0.0015 18.2 0.4 0.01 15.5 0.2 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 GAK64920.1 - 0.0022 17.8 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 GAK64920.1 - 0.0075 16.1 0.1 0.0089 15.9 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF836 PF05768.14 GAK64920.1 - 0.028 14.8 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.11 GAK64920.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE KaiB PF07689.12 GAK64920.1 - 0.055 13.2 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 KaiB domain Glutaredoxin PF00462.24 GAK64920.1 - 0.16 12.2 1.0 0.35 11.1 1.0 1.7 1 1 0 1 1 1 0 Glutaredoxin zf-CCHC PF00098.23 GAK64922.1 - 6.5e-29 98.7 40.9 3.1e-08 33.3 3.4 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 GAK64922.1 - 2.9e-09 36.5 22.7 0.024 14.3 0.7 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 GAK64922.1 - 0.00057 19.8 28.9 0.16 11.9 1.9 5.1 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 GAK64922.1 - 0.52 10.2 37.9 0.37 10.6 1.3 5.3 5 0 0 5 5 5 0 Zinc knuckle Adaptin_N PF01602.20 GAK64923.1 - 9.1e-123 410.6 11.6 1.1e-122 410.3 11.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GAK64923.1 - 2e-40 137.5 0.0 5.1e-40 136.2 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 GAK64923.1 - 4.6e-13 49.5 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain 14-3-3 PF00244.20 GAK64924.1 - 1.3e-107 358.4 4.2 1.6e-107 358.1 4.2 1.1 1 0 0 1 1 1 1 14-3-3 protein Ras PF00071.22 GAK64925.1 - 3.3e-50 169.9 0.0 3.9e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK64925.1 - 2.9e-30 105.0 0.0 4.4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK64925.1 - 2.5e-10 40.1 0.0 3.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAK64925.1 - 8.4e-05 22.0 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK64925.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAK64925.1 - 0.0011 18.2 0.7 0.37 9.9 0.1 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.12 GAK64925.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 GAK64925.1 - 0.017 15.5 0.1 0.14 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 GAK64925.1 - 0.028 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF5118 PF17162.4 GAK64925.1 - 0.037 13.8 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) RsgA_GTPase PF03193.16 GAK64925.1 - 0.049 13.5 0.0 6.6 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAK64925.1 - 0.052 13.9 0.0 0.098 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 GAK64925.1 - 0.055 13.2 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAK64925.1 - 0.094 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAK64925.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.21 GAK64925.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain Septin PF00735.18 GAK64925.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin ATPase PF06745.13 GAK64925.1 - 0.18 11.1 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 KaiC RPA43_OB PF17875.1 GAK64926.1 - 5.1e-22 78.8 3.8 6e-14 52.7 0.0 3.5 3 1 1 4 4 4 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 GAK64926.1 - 7.1e-05 23.1 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 YabA PF06156.13 GAK64927.1 - 0.036 14.7 1.0 0.036 14.7 1.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 GAK64927.1 - 0.29 11.4 2.0 0.94 9.7 2.0 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.6 GAK64927.1 - 1.1 9.4 4.1 0.71 10.0 1.4 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain NRBF2 PF08961.10 GAK64927.1 - 3.3 7.3 11.4 0.24 11.0 0.9 2.7 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator FUSC PF04632.12 GAK64930.1 - 2.1e-14 53.0 7.9 2.1e-14 53.0 7.9 2.9 3 0 0 3 3 3 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 GAK64930.1 - 3.1e-14 53.2 7.3 3.1e-14 53.2 7.3 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 GAK64930.1 - 2.6e-08 33.2 4.9 3.9e-08 32.6 3.2 2.0 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 GAK64930.1 - 3.9e-06 26.2 0.0 0.00011 21.4 0.0 2.4 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_1 PF06081.11 GAK64930.1 - 1e-05 25.7 2.9 1e-05 25.7 2.9 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 ArAE_2 PF10334.9 GAK64930.1 - 3.3e-05 23.8 1.1 3.3e-05 23.8 1.1 1.6 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FCD PF07729.12 GAK64930.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.7 3 0 0 3 3 3 0 FCD domain MnmE_helical PF12631.7 GAK64931.1 - 1.9e-36 126.2 0.0 3.4e-36 125.4 0.0 1.4 1 1 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 GAK64931.1 - 2.1e-31 108.6 0.1 5.3e-31 107.3 0.1 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 GAK64931.1 - 7.7e-20 71.1 0.0 1.8e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK64931.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAK64931.1 - 0.00031 20.8 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 GAK64931.1 - 0.0025 18.1 0.1 0.039 14.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAK64931.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 GAK64931.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAK64931.1 - 0.047 14.1 0.2 0.4 11.1 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 GAK64931.1 - 0.062 12.9 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PTH2 PF01981.16 GAK64932.1 - 5.2e-06 26.7 0.7 2.4e-05 24.6 0.7 1.9 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 CotJB PF12652.7 GAK64932.1 - 0.12 12.6 0.3 1 9.6 0.1 2.1 2 0 0 2 2 2 0 CotJB protein Sybindin PF04099.12 GAK64933.1 - 4.8e-38 130.3 0.0 6.3e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 GAK64933.1 - 2e-07 31.2 0.0 2.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region eIF3m_C_helix PF18005.1 GAK64934.1 - 5.5e-13 48.4 0.1 5.5e-13 48.4 0.1 1.9 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 GAK64934.1 - 1e-10 42.1 0.0 2.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain CTP_transf_like PF01467.26 GAK64935.1 - 9.6e-06 25.9 0.1 4.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like Hamartin PF04388.12 GAK64935.1 - 0.51 8.9 5.4 0.82 8.3 5.4 1.4 1 0 0 1 1 1 0 Hamartin protein JAKMIP_CC3 PF16034.5 GAK64935.1 - 1.4 8.8 6.3 0.63 10.0 3.0 2.1 2 1 0 2 2 2 0 JAKMIP CC3 domain Coatomer_E PF04733.14 GAK64936.1 - 1.1e-42 146.4 5.4 1.3e-42 146.2 5.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_20 PF14561.6 GAK64936.1 - 0.035 14.4 0.5 0.035 14.4 0.5 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK64936.1 - 0.082 13.8 1.1 0.082 13.8 1.1 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Mak16 PF04874.14 GAK64936.1 - 0.17 12.5 0.1 0.31 11.6 0.1 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region TPR_17 PF13431.6 GAK64936.1 - 0.3 11.5 2.5 0.64 10.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAK64936.1 - 2.8 8.5 19.2 5.5 7.6 3.4 4.6 3 3 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK64936.1 - 5.8 7.2 8.5 8.8 6.6 0.1 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Hist_deacetyl PF00850.19 GAK64937.1 - 5.5e-80 269.1 0.0 9.2e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain ELYS PF13934.6 GAK64938.1 - 3e-43 148.3 1.6 4.3e-43 147.9 1.6 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF3237 PF11578.8 GAK64939.1 - 1.3e-32 112.7 0.0 1.5e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Glypican PF01153.19 GAK64940.1 - 1.3 7.8 11.0 2.5 6.8 11.0 1.4 1 0 0 1 1 1 0 Glypican CBS PF00571.28 GAK64941.1 - 7.8e-19 67.9 5.6 0.00022 21.6 0.1 5.4 5 0 0 5 5 5 4 CBS domain F-box-like PF12937.7 GAK64942.1 - 3.6e-11 42.8 3.6 3.6e-11 42.8 3.6 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GAK64942.1 - 5.1e-06 26.7 6.3 0.46 11.0 0.0 6.6 5 1 3 8 8 8 3 Leucine Rich repeats (2 copies) F-box PF00646.33 GAK64942.1 - 3.4e-05 23.6 6.6 4.9e-05 23.1 1.2 3.4 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 GAK64942.1 - 0.00011 22.0 20.9 0.87 9.8 0.1 9.2 11 0 0 11 11 11 2 Leucine Rich repeat SAM_Ste50p PF09235.10 GAK64942.1 - 0.16 12.3 1.5 38 4.6 0.0 3.6 3 0 0 3 3 3 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 GAK64942.1 - 1.7 9.5 12.5 1.4e+02 3.7 0.0 7.0 8 1 0 8 8 8 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 GAK64943.1 - 6.1e-08 32.7 1.0 0.00044 20.4 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAK64943.1 - 0.00031 20.9 0.2 0.016 15.4 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF3915 PF13054.6 GAK64943.1 - 2.3 8.2 4.2 2.8 7.9 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF4770 PF15994.5 GAK64943.1 - 5.2 7.3 7.4 3.1 8.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) P21-Arc PF04062.14 GAK64945.1 - 2.3e-77 258.9 0.0 2.6e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Methyltransf_16 PF10294.9 GAK64946.1 - 5e-14 52.4 0.0 8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAK64946.1 - 0.0002 20.8 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TMEM70 PF06979.12 GAK64946.1 - 0.0049 17.3 0.1 0.0085 16.5 0.1 1.4 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Methyltransf_25 PF13649.6 GAK64946.1 - 0.0086 16.8 0.0 0.03 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TetR_C_7 PF14246.6 GAK64946.1 - 0.039 14.0 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain MTS PF05175.14 GAK64946.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NIF PF03031.18 GAK64947.1 - 6.1e-44 149.5 0.0 9.1e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MID_MedPIWI PF18296.1 GAK64947.1 - 0.32 10.7 2.4 0.58 9.9 2.4 1.4 1 0 0 1 1 1 0 MID domain of medPIWI Asp_protease PF09668.10 GAK64948.1 - 1.2e-58 196.3 0.0 1.8e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAK64948.1 - 8.8e-23 80.7 0.0 2.2e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAK64948.1 - 5.3e-12 46.2 0.2 2.1e-11 44.3 0.0 2.2 2 1 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 GAK64948.1 - 1.9e-11 43.5 0.0 3.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 GAK64948.1 - 4e-05 23.3 0.3 9.1e-05 22.2 0.3 1.7 1 0 0 1 1 1 1 UBA-like domain Rad60-SLD PF11976.8 GAK64948.1 - 0.00059 19.6 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.20 GAK64948.1 - 0.0024 18.2 0.0 0.0054 17.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 GAK64948.1 - 0.0074 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease FlgN PF05130.12 GAK64948.1 - 0.011 16.3 0.7 0.031 14.8 0.7 1.8 1 0 0 1 1 1 0 FlgN protein XPC-binding PF09280.11 GAK64948.1 - 0.02 14.6 4.9 0.054 13.2 4.9 1.7 1 0 0 1 1 1 0 XPC-binding domain UBA PF00627.31 GAK64948.1 - 0.032 14.1 0.7 0.15 12.0 0.1 2.5 2 0 0 2 2 2 0 UBA/TS-N domain Bep_C_terminal PF17841.1 GAK64948.1 - 0.056 13.7 0.5 3.6 7.9 0.2 2.6 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) Mob1_phocein PF03637.17 GAK64949.1 - 6.6e-60 202.0 0.2 8e-60 201.7 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family ABC_tran PF00005.27 GAK64950.1 - 8.9e-45 152.6 0.0 4.5e-22 79.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAK64950.1 - 2.4e-21 75.6 2.9 2.4e-21 75.6 2.9 2.7 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 GAK64950.1 - 6.9e-17 62.2 6.1 0.0004 20.3 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAK64950.1 - 1.2e-08 35.1 0.0 0.029 14.1 0.1 3.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAK64950.1 - 7e-08 32.1 1.0 0.0026 17.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 GAK64950.1 - 1.2e-07 31.4 2.4 0.49 9.8 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAK64950.1 - 1.9e-07 31.8 19.4 0.00063 20.3 1.8 4.5 4 1 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 GAK64950.1 - 1.4e-06 28.3 1.2 0.004 17.1 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 GAK64950.1 - 8.1e-06 26.0 5.0 0.092 12.8 0.0 4.4 2 1 0 3 3 3 2 Dynamin family AAA_16 PF13191.6 GAK64950.1 - 2.3e-05 24.9 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAK64950.1 - 6e-05 23.1 5.6 0.0024 17.9 0.1 3.6 4 1 0 4 4 2 1 50S ribosome-binding GTPase NACHT PF05729.12 GAK64950.1 - 8.7e-05 22.5 0.9 0.45 10.4 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 GAK64950.1 - 9.7e-05 22.2 0.2 1.1 8.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 GAK64950.1 - 0.00012 22.3 0.3 0.34 11.2 0.1 3.2 2 2 1 3 3 3 1 AAA domain FeoB_N PF02421.18 GAK64950.1 - 0.00087 18.8 0.1 0.078 12.5 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_30 PF13604.6 GAK64950.1 - 0.00093 19.0 0.1 0.36 10.5 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 GAK64950.1 - 0.001 19.5 1.6 4.5 7.7 0.0 4.1 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAK64950.1 - 0.0011 19.2 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAK64950.1 - 0.0023 17.5 0.1 4.9 6.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 GAK64950.1 - 0.0046 17.2 0.0 5.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 GAK64950.1 - 0.0083 16.7 0.3 8.3 7.0 0.1 3.1 3 1 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 GAK64950.1 - 0.017 14.6 0.9 2.2 7.7 0.1 2.8 2 1 1 3 3 3 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 GAK64950.1 - 0.018 14.4 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 GAK64950.1 - 0.02 14.1 0.1 0.73 9.0 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.14 GAK64950.1 - 0.02 14.9 0.4 1.1 9.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAK64950.1 - 0.021 14.8 0.2 34 4.5 0.0 4.0 4 1 1 5 5 5 0 AAA domain AAA_33 PF13671.6 GAK64950.1 - 0.037 14.2 0.3 16 5.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 GAK64950.1 - 0.038 13.6 0.3 6.5 6.3 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAK64950.1 - 0.039 14.4 0.5 4 7.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase DAP3 PF10236.9 GAK64950.1 - 0.059 12.5 1.2 7 5.7 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 GAK64950.1 - 0.071 12.6 0.4 2 7.9 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region T2SSE PF00437.20 GAK64950.1 - 0.084 11.9 0.4 9.8 5.1 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF87 PF01935.17 GAK64950.1 - 0.11 12.5 8.3 0.97 9.5 0.0 4.2 3 1 1 4 4 4 0 Helicase HerA, central domain SRP54 PF00448.22 GAK64950.1 - 0.15 11.7 3.5 1.8 8.1 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 GAK64950.1 - 0.47 10.4 4.7 1.9 8.4 0.1 3.5 4 0 0 4 4 3 0 NTPase Ribosomal_L23eN PF03939.13 GAK64950.1 - 0.48 10.7 4.1 1.2 9.4 4.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain DivIC PF04977.15 GAK64950.1 - 1.9 8.3 14.9 1.4 8.7 1.7 3.1 3 0 0 3 3 3 0 Septum formation initiator DLIC PF05783.11 GAK64950.1 - 3.1 6.5 10.3 4.3 6.0 0.0 3.2 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) MRP-L27 PF09809.9 GAK64951.1 - 7.5e-05 22.5 1.6 0.0034 17.2 1.6 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 LEA_5 PF00477.17 GAK64951.1 - 0.052 14.0 0.1 0.16 12.4 0.0 1.7 1 1 1 2 2 2 0 Small hydrophilic plant seed protein SPRY PF00622.28 GAK64953.1 - 7.3e-06 26.1 0.0 0.00019 21.5 0.0 2.7 3 0 0 3 3 3 1 SPRY domain DUF3827 PF12877.7 GAK64953.1 - 1.8 6.9 6.5 3.7 5.8 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DEAD PF00270.29 GAK64955.1 - 7.4e-41 139.8 0.0 1.6e-40 138.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK64955.1 - 2.7e-23 82.4 0.0 1.1e-22 80.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK64955.1 - 0.00053 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AP3D1 PF06375.11 GAK64955.1 - 0.24 11.6 6.3 1 9.6 0.2 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Erv26 PF04148.13 GAK64956.1 - 4.2e-11 43.1 0.2 1e-10 41.8 0.2 1.5 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Cyt_bd_oxida_II PF02322.15 GAK64956.1 - 0.17 11.2 6.9 0.26 10.6 6.9 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Acyl-CoA_dh_N PF02771.16 GAK64957.1 - 2.8e-27 95.6 0.0 5.2e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAK64957.1 - 2.2e-24 86.4 0.0 3.5e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAK64957.1 - 8.7e-21 73.9 0.8 1.4e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAK64957.1 - 1.9e-08 34.7 0.4 4.4e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Mod_r PF07200.13 GAK64959.1 - 7.7e-28 97.4 5.1 7.7e-28 97.4 5.1 1.7 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein NUDIX PF00293.28 GAK64960.1 - 1.2e-10 41.5 0.0 3.8e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain RTP1_C1 PF10363.9 GAK64961.1 - 1e-31 109.4 0.2 3e-31 107.9 0.0 2.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 GAK64961.1 - 4.3e-05 23.1 1.5 0.00022 20.8 1.5 2.3 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 YihI PF04220.12 GAK64961.1 - 0.062 13.0 0.8 0.15 11.8 0.8 1.6 1 0 0 1 1 1 0 Der GTPase activator (YihI) AAA_16 PF13191.6 GAK64961.1 - 0.23 11.9 7.6 0.23 11.8 3.6 3.2 2 2 0 2 2 2 0 AAA ATPase domain HEAT_EZ PF13513.6 GAK64961.1 - 0.57 10.8 9.1 6 7.5 0.2 4.7 4 1 0 4 4 4 0 HEAT-like repeat Iso_dh PF00180.20 GAK64962.1 - 1.3e-79 267.9 0.0 1.6e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.20 GAK64963.1 - 1.8e-101 339.8 0.0 2.2e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COesterase PF00135.28 GAK64964.1 - 1.1e-63 216.0 0.0 1.5e-62 212.2 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family zf-CSL PF05207.13 GAK64964.1 - 2.7e-11 43.0 0.8 5.3e-11 42.1 0.8 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 GAK64964.1 - 1.2e-10 41.4 0.1 1.8e-09 37.6 0.1 2.6 2 1 0 2 2 2 1 DnaJ domain Abhydrolase_3 PF07859.13 GAK64964.1 - 7e-05 22.8 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold ZZ PF00569.17 GAK64964.1 - 0.04 13.7 0.3 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type zinc_ribbon_4 PF13717.6 GAK64964.1 - 0.3 11.0 0.6 0.58 10.1 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RRM_1 PF00076.22 GAK64965.1 - 5.6e-14 51.7 0.0 7.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK64965.1 - 0.052 13.1 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18 PF17135.4 GAK64966.1 - 2.5e-88 294.4 2.0 3.5e-88 293.9 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAK64966.1 - 0.0019 18.9 0.9 0.0029 18.3 0.0 2.0 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Adenylate_cycl PF01295.18 GAK64966.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Isy1 PF06246.12 GAK64967.1 - 6.8e-89 297.8 1.2 8.5e-89 297.5 1.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family VID27 PF08553.10 GAK64968.1 - 5e-164 545.5 0.0 7e-164 545.1 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 GAK64968.1 - 4.6e-56 189.4 0.5 4.6e-56 189.4 0.5 2.9 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 GAK64968.1 - 1.1e-32 112.6 5.3 3.7e-32 110.8 3.8 2.4 2 0 0 2 2 2 1 VID27 PH-like domain eIF-3_zeta PF05091.12 GAK64969.1 - 2e-202 673.8 0.0 2.2e-202 673.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Keratin_2_head PF16208.5 GAK64969.1 - 1.9 8.6 26.6 3.9 7.6 26.6 1.4 1 0 0 1 1 1 0 Keratin type II head Pkinase PF00069.25 GAK64970.1 - 2e-42 145.4 0.0 7.7e-22 77.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAK64970.1 - 1.3e-11 44.3 0.0 8.2e-09 35.1 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 GAK64970.1 - 0.0014 18.6 0.9 0.013 15.4 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 GAK64970.1 - 0.18 11.1 0.0 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAP18 PF06487.12 GAK64971.1 - 2.3e-26 92.7 0.0 3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Ribosomal_L7Ae PF01248.26 GAK64972.1 - 5.9e-28 96.5 0.8 7.4e-28 96.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Clathrin_lg_ch PF01086.17 GAK64973.1 - 1.6e-43 149.4 5.8 2.6e-43 148.7 5.8 1.3 1 0 0 1 1 1 1 Clathrin light chain Ribosomal_S17 PF00366.20 GAK64973.1 - 6.5e-26 90.2 2.2 1.3e-25 89.2 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 GAK64973.1 - 9e-22 77.2 6.9 5e-15 55.6 0.6 3.1 3 0 0 3 3 3 2 Ribosomal_S17 N-terminal Metallophos PF00149.28 GAK64974.1 - 1.6e-39 136.5 0.3 2.5e-39 135.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAK64974.1 - 0.0011 19.3 0.2 0.0022 18.4 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 GAK64974.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FAD-oxidase_C PF02913.19 GAK64975.1 - 3.9e-63 213.4 0.0 5.6e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Cid2 PF09774.9 GAK64975.1 - 5.8e-36 124.3 0.4 9.8e-36 123.6 0.4 1.4 1 0 0 1 1 1 1 Caffeine-induced death protein 2 FAD_binding_4 PF01565.23 GAK64975.1 - 5.4e-35 120.1 1.1 9.3e-35 119.4 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain Ilar_coat PF01787.16 GAK64975.1 - 0.025 14.4 0.0 0.49 10.2 0.0 2.4 2 0 0 2 2 2 0 Ilarvirus coat protein Glyoxalase_6 PF18029.1 GAK64975.1 - 0.074 13.8 0.1 0.17 12.7 0.1 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain Clathrin PF00637.20 GAK64976.1 - 1.3e-24 86.7 0.2 9.6e-24 83.9 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_14 PF13428.6 GAK64976.1 - 4.3 8.4 6.4 39 5.4 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAK64976.1 - 4.3 7.7 4.6 4.9 7.5 0.5 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GRIM-19 PF06212.12 GAK64977.1 - 3e-35 121.1 0.0 3.6e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein Coiled-coil_56 PF09813.9 GAK64977.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Nop14 PF04147.12 GAK64978.1 - 0 1017.2 12.5 0 1016.9 12.5 1.0 1 0 0 1 1 1 1 Nop14-like family TIP41 PF04176.13 GAK64979.1 - 1.3e-47 161.5 0.0 7.9e-47 158.9 0.0 2.0 1 1 0 1 1 1 1 TIP41-like family zf-CCCH_4 PF18044.1 GAK64980.1 - 2.9e-09 36.5 2.5 5.5e-09 35.6 2.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAK64980.1 - 5.6e-06 26.2 6.5 1.1e-05 25.2 6.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAK64980.1 - 1.9e-05 24.4 1.3 3.4e-05 23.6 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2722 PF10846.8 GAK64980.1 - 0.0086 15.1 6.4 0.013 14.4 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 GAK64980.1 - 0.026 14.6 19.8 0.037 14.0 19.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH_2 PF14608.6 GAK64980.1 - 0.31 11.6 6.2 0.55 10.8 6.2 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PEHE PF15275.6 GAK64980.1 - 1.1 9.9 5.1 2.2 8.9 5.1 1.4 1 0 0 1 1 1 0 PEHE domain Jak1_Phl PF17887.1 GAK64980.1 - 1.4 8.9 6.2 2.1 8.3 6.2 1.1 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Coilin_N PF15862.5 GAK64980.1 - 2.5 7.9 7.8 3.6 7.4 7.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus Spt20 PF12090.8 GAK64980.1 - 2.8 7.5 20.4 4.1 6.9 20.4 1.2 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 GAK64980.1 - 3.3 6.7 6.2 5.1 6.1 6.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 GAK64980.1 - 4.2 6.0 6.5 5.8 5.6 6.5 1.1 1 0 0 1 1 1 0 Presenilin Rrn6 PF10214.9 GAK64980.1 - 8.3 4.8 9.6 13 4.1 9.6 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.32 GAK64981.1 - 6.9e-12 45.7 8.1 0.49 11.4 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK64981.1 - 2.8e-06 27.5 0.0 0.025 14.9 0.0 3.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain YccV-like PF08755.11 GAK64982.1 - 7.3e-17 61.7 0.0 2.7e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 GAK64982.1 - 1.2e-12 47.7 0.0 1.9e-11 43.8 0.0 2.8 3 0 0 3 3 3 1 Transglutaminase-like superfamily F-box-like PF12937.7 GAK64982.1 - 4.4e-08 32.9 0.0 1.5e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK64982.1 - 0.0001 22.1 0.2 0.00048 19.9 0.0 2.3 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 GAK64982.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box NOB1_Zn_bind PF08772.11 GAK64983.1 - 1.5e-31 108.3 1.9 3.1e-31 107.3 1.9 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 GAK64983.1 - 1.6e-24 86.2 0.0 4.4e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease DZR PF12773.7 GAK64983.1 - 0.11 12.5 1.8 0.21 11.6 1.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon OGG_N PF07934.12 GAK64984.1 - 7.6e-26 90.6 0.0 1.5e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 GAK64984.1 - 3.4e-15 56.4 0.0 8.8e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAK64984.1 - 0.0044 16.8 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GAK64984.1 - 0.15 12.7 0.1 5.1 7.8 0.0 3.0 3 1 0 3 3 3 0 Helix-hairpin-helix domain GLE1 PF07817.13 GAK64985.1 - 1.1e-76 257.4 0.1 1.5e-76 257.0 0.1 1.2 1 0 0 1 1 1 1 GLE1-like protein Sec62 PF03839.16 GAK64985.1 - 0.84 9.1 2.7 1.9 8.0 2.7 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 GRP PF07172.11 GAK64986.1 - 2.6 8.8 21.0 4.8 7.9 21.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family DUF4141 PF13605.6 GAK64987.1 - 0.093 12.0 0.5 0.17 11.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) AAA PF00004.29 GAK64989.1 - 2.7e-92 306.1 0.0 2.6e-46 157.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK64989.1 - 4.5e-23 80.8 3.9 1.8e-11 43.6 0.7 2.8 2 1 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 GAK64989.1 - 1.1e-14 54.5 0.0 2.7e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAK64989.1 - 1.2e-11 44.7 0.7 0.00048 20.1 0.2 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAK64989.1 - 1.1e-10 41.9 0.0 0.00055 20.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAK64989.1 - 7.6e-10 39.2 1.5 0.012 15.9 0.0 4.8 2 2 2 4 4 3 2 AAA domain AAA_16 PF13191.6 GAK64989.1 - 1.1e-09 38.9 11.6 0.00013 22.4 0.1 5.1 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 GAK64989.1 - 3.1e-09 37.1 0.0 0.0029 17.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 GAK64989.1 - 5.1e-09 35.8 0.4 0.00026 20.3 0.1 2.9 2 1 1 3 3 3 2 TIP49 P-loop domain Mg_chelatase PF01078.21 GAK64989.1 - 3.9e-07 29.7 0.4 0.034 13.5 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAK64989.1 - 7.2e-07 29.3 0.0 0.021 14.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 GAK64989.1 - 1.8e-06 28.2 0.0 0.071 13.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 GAK64989.1 - 3.4e-06 27.1 1.8 0.073 13.0 0.1 4.1 3 1 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.17 GAK64989.1 - 4.4e-06 26.6 0.1 0.034 13.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 GAK64989.1 - 1e-05 26.1 0.0 0.038 14.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 GAK64989.1 - 1.8e-05 25.0 0.0 0.31 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 GAK64989.1 - 1.9e-05 24.5 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 GAK64989.1 - 2.9e-05 24.1 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 GAK64989.1 - 4.1e-05 23.8 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_18 PF13238.6 GAK64989.1 - 8.8e-05 23.1 0.0 0.4 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAK64989.1 - 9.4e-05 22.1 2.2 0.83 9.2 0.2 3.9 3 1 1 4 4 4 2 AAA domain ATPase PF06745.13 GAK64989.1 - 0.00013 21.4 0.1 1.4 8.2 0.0 3.3 3 0 0 3 3 3 1 KaiC Rad17 PF03215.15 GAK64989.1 - 0.00019 21.4 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_17 PF13207.6 GAK64989.1 - 0.00026 21.4 0.1 0.37 11.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 GAK64989.1 - 0.0003 20.3 0.0 0.54 9.7 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAK64989.1 - 0.00031 20.5 0.1 0.44 10.2 0.0 3.4 4 0 0 4 4 4 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 GAK64989.1 - 0.00038 19.8 0.2 0.65 9.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Viral_helicase1 PF01443.18 GAK64989.1 - 0.00055 19.7 0.0 0.98 9.1 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 GAK64989.1 - 0.00066 19.5 0.0 0.77 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GAK64989.1 - 0.00087 18.6 0.0 0.84 8.8 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain DUF815 PF05673.13 GAK64989.1 - 0.0012 18.1 0.0 0.025 13.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 GAK64989.1 - 0.0025 17.9 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Vps4_C PF09336.10 GAK64989.1 - 0.0035 17.3 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 GAK64989.1 - 0.0035 17.1 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 GAK64989.1 - 0.0039 16.1 0.0 0.67 8.8 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase PhoH PF02562.16 GAK64989.1 - 0.0053 16.2 0.4 2.3 7.6 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein ATPase_2 PF01637.18 GAK64989.1 - 0.015 15.3 0.0 1.9 8.3 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 GAK64989.1 - 0.018 14.4 0.0 20 4.5 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein SKI PF01202.22 GAK64989.1 - 0.02 15.0 0.1 6.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Parvo_NS1 PF01057.17 GAK64989.1 - 0.02 14.0 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 GAK64989.1 - 0.05 13.5 0.1 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 GAK64989.1 - 0.12 12.8 0.9 13 6.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAK64989.1 - 0.14 11.9 0.0 9.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 GAK64989.1 - 0.18 11.8 0.0 30 4.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UBM PF14377.6 GAK64989.1 - 3.2 7.3 7.8 1.2 8.7 0.0 3.7 4 0 0 4 4 3 0 Ubiquitin binding region TB2_DP1_HVA22 PF03134.19 GAK64990.1 - 3.2e-08 33.4 0.6 6e-08 32.5 0.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family IMS PF00817.20 GAK64991.1 - 1.4e-40 138.7 0.0 3.6e-40 137.4 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family Cyt-b5 PF00173.28 GAK64991.1 - 8.6e-23 80.3 0.0 2.5e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMS_C PF11799.8 GAK64991.1 - 1.7e-14 54.5 0.0 3.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 GAK64991.1 - 6.3e-06 25.5 0.2 1.8e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin binding region IMS_HHH PF11798.8 GAK64991.1 - 0.054 13.8 0.0 0.25 11.8 0.0 2.3 1 1 0 1 1 1 0 IMS family HHH motif CSN8_PSD8_EIF3K PF10075.9 GAK64993.1 - 4e-27 95.0 0.1 7.6e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TRAPP PF04051.16 GAK64994.1 - 1.4e-33 115.7 0.0 2.2e-33 115.0 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component He_PIG PF05345.12 GAK64995.1 - 1.1e-06 28.7 27.5 0.0011 19.1 2.7 5.0 4 1 0 4 4 4 3 Putative Ig domain PP2C PF00481.21 GAK64998.1 - 2.7e-33 115.7 0.0 3.7e-30 105.4 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAK64998.1 - 0.026 14.2 0.0 0.064 12.9 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C BrkDBD PF09607.10 GAK64998.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain NUDIX PF00293.28 GAK64999.1 - 7.9e-12 45.4 0.3 1.1e-11 44.9 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.29 GAK65000.1 - 6.1e-54 182.0 0.0 8.2e-38 129.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 GAK65000.1 - 2e-10 40.3 0.7 2.8e-09 36.6 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 GAK65000.1 - 1.4e-09 38.6 0.3 0.0018 18.7 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAK65000.1 - 2e-09 37.9 0.8 0.0024 18.1 0.0 4.0 3 2 1 4 4 4 2 AAA domain AAA_lid_3 PF17862.1 GAK65000.1 - 2.6e-09 36.8 0.1 5.5e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAK65000.1 - 4.3e-08 33.2 0.0 0.0019 18.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAK65000.1 - 6.1e-08 33.0 0.1 0.00043 20.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAK65000.1 - 1.2e-07 31.6 0.3 0.01 15.6 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAK65000.1 - 4e-07 29.6 0.0 0.0063 15.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 GAK65000.1 - 4.2e-07 30.0 0.2 0.034 14.1 0.0 3.7 3 1 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 GAK65000.1 - 6.1e-07 29.4 0.1 0.02 14.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAK65000.1 - 1.2e-06 28.7 0.0 0.044 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAK65000.1 - 1.6e-06 27.7 0.5 0.01 15.2 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAK65000.1 - 5.9e-06 26.1 0.0 0.032 13.9 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 GAK65000.1 - 6.5e-06 26.5 0.0 0.031 14.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 GAK65000.1 - 2.5e-05 24.8 0.6 0.19 12.3 0.1 3.3 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 GAK65000.1 - 3.1e-05 24.5 0.0 0.066 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAK65000.1 - 3.9e-05 23.7 0.0 0.098 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 GAK65000.1 - 4.4e-05 23.5 0.6 1.4 8.8 0.1 3.7 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea TsaE PF02367.17 GAK65000.1 - 5e-05 23.3 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAK65000.1 - 5e-05 23.6 0.0 0.073 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GAK65000.1 - 6.8e-05 22.2 0.0 0.42 9.8 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.16 GAK65000.1 - 0.00016 21.2 0.0 0.51 9.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 GAK65000.1 - 0.00023 21.0 0.0 0.32 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 GAK65000.1 - 0.00031 20.5 0.0 0.64 9.7 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 GAK65000.1 - 0.00047 19.6 0.1 0.13 11.6 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 GAK65000.1 - 0.00061 19.4 1.8 0.89 9.1 0.0 3.4 3 1 0 4 4 3 2 AAA domain Parvo_NS1 PF01057.17 GAK65000.1 - 0.00064 18.9 0.0 0.58 9.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 GAK65000.1 - 0.00081 19.2 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAK65000.1 - 0.00087 18.8 0.1 0.2 11.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 GAK65000.1 - 0.0022 18.3 0.8 1.5 9.1 0.1 2.9 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.9 GAK65000.1 - 0.0032 16.8 0.3 1.7 7.8 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 GAK65000.1 - 0.0039 17.1 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 GAK65000.1 - 0.0058 17.0 0.2 4 7.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain DAP3 PF10236.9 GAK65000.1 - 0.013 14.7 0.0 4.5 6.3 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 GAK65000.1 - 0.015 14.6 0.1 0.49 9.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 GAK65000.1 - 0.052 13.1 0.1 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 GAK65000.1 - 0.056 13.2 1.3 31 4.3 0.0 3.7 2 2 2 4 4 4 0 DEAD/DEAH box helicase KTI12 PF08433.10 GAK65000.1 - 0.096 12.1 0.1 6.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ResIII PF04851.15 GAK65000.1 - 0.12 12.3 0.2 47 3.9 0.0 3.4 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 GAK65000.1 - 0.14 12.1 0.1 18 5.2 0.0 2.6 2 0 0 2 2 2 0 NTPase Hydin_ADK PF17213.3 GAK65000.1 - 0.16 12.2 0.3 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain TCTP PF00838.17 GAK65001.1 - 1.2e-69 233.9 0.1 1.6e-69 233.5 0.1 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein Zn_clus PF00172.18 GAK65002.1 - 6.1 7.1 9.3 1.7 8.8 1.7 2.3 1 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP PF00616.19 GAK65003.1 - 1.1e-22 80.8 0.0 4.5e-15 55.9 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAK65003.1 - 7.5e-06 26.1 1.4 2e-05 24.8 0.1 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain ImpA_N PF06812.12 GAK65003.1 - 0.016 15.3 0.0 0.067 13.3 0.0 2.1 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system LisH PF08513.11 GAK65005.1 - 9.7e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 LisH Ribosomal_S13 PF00416.22 GAK65006.1 - 2.8e-19 69.8 0.3 3e-18 66.4 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAK65006.1 - 0.00027 19.8 0.0 0.00045 19.1 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) EF-hand_1 PF00036.32 GAK65007.1 - 3e-27 92.1 11.3 9e-08 31.1 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAK65007.1 - 1.3e-22 80.0 5.9 7.4e-13 48.7 0.9 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAK65007.1 - 1.9e-21 74.1 8.9 2e-05 24.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAK65007.1 - 1.5e-19 68.5 12.9 4.1e-07 29.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAK65007.1 - 1.4e-13 50.4 13.4 0.00041 20.1 0.4 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAK65007.1 - 5.4e-06 26.7 0.0 0.019 15.3 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAK65007.1 - 5.4e-06 26.6 0.0 0.17 12.3 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 GAK65007.1 - 1.8e-05 24.6 6.3 0.0066 16.4 0.3 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 GAK65007.1 - 0.11 12.7 3.6 2.1 8.6 3.1 2.8 2 1 0 2 2 2 0 Dockerin type I domain VCBS PF13517.6 GAK65007.1 - 0.14 12.8 1.1 15 6.3 0.1 2.5 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TM231 PF10149.9 GAK65007.1 - 0.16 11.3 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 231 Proteasome PF00227.26 GAK65008.1 - 2.6e-42 144.5 0.2 2.9e-42 144.3 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Vta1 PF04652.16 GAK65008.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Vta1 like Vac14_Fig4_bd PF11916.8 GAK65009.1 - 2.4e-79 265.1 8.5 2.4e-79 265.1 8.5 2.5 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 GAK65009.1 - 7.5e-44 148.3 0.0 1.3e-39 134.7 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAK65009.1 - 3.4e-11 42.4 5.9 0.0019 18.3 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 GAK65009.1 - 1.8e-07 31.4 0.6 0.014 15.5 0.2 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAK65009.1 - 1.5e-05 25.3 5.0 1.8 9.2 0.0 5.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 GAK65009.1 - 0.00011 22.6 8.6 0.5 10.8 0.0 5.7 5 2 1 6 6 6 2 HEAT repeats MMS19_C PF12460.8 GAK65009.1 - 0.0012 18.0 5.9 0.031 13.4 0.0 3.3 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 GAK65009.1 - 0.0014 18.3 0.0 17 4.9 0.0 4.3 3 1 1 4 4 4 0 CLASP N terminal TFIIE-A_C PF11521.8 GAK65009.1 - 0.014 15.7 1.5 0.04 14.2 1.5 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha CENP-B_dimeris PF09026.10 GAK65009.1 - 0.016 15.6 1.6 0.034 14.5 1.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tti2 PF10521.9 GAK65009.1 - 0.021 14.4 0.4 4.3 6.8 0.0 3.7 3 1 1 4 4 4 0 Tti2 family ParcG PF10274.9 GAK65009.1 - 0.023 14.8 0.1 3.8 7.6 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein UCH PF00443.29 GAK65010.1 - 2.7e-48 164.7 0.0 4e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK65010.1 - 4e-20 72.6 0.0 9e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 GAK65010.1 - 0.0027 17.2 0.0 0.026 14.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Zn-ribbon_8 PF09723.10 GAK65010.1 - 0.18 11.9 0.6 21 5.4 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 GAK65010.1 - 0.27 11.3 1.6 1.2 9.2 1.6 2.0 1 1 0 1 1 1 0 Double zinc ribbon TBCA PF02970.16 GAK65011.1 - 1.1e-21 77.0 1.2 1.5e-21 76.5 0.7 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A PDEase_I PF00233.19 GAK65011.1 - 0.096 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Orbi_VP5 PF00901.17 GAK65011.1 - 0.1 11.0 1.3 0.11 10.9 1.3 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 RRM_1 PF00076.22 GAK65012.1 - 3.3e-27 94.1 0.1 5.1e-16 58.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAK65012.1 - 7.8e-05 22.6 0.0 0.00054 19.9 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAK65012.1 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_7 PF16367.5 GAK65012.1 - 0.014 15.5 0.0 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 GAK65012.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Cpn60_TCP1 PF00118.24 GAK65013.1 - 4.4e-152 507.1 12.7 5e-152 507.0 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 GAK65013.1 - 0.0019 17.8 0.1 0.0062 16.1 0.1 1.9 2 0 0 2 2 2 1 Telomere recombination LSM PF01423.22 GAK65014.1 - 6.2e-21 73.9 0.0 6.9e-21 73.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAK65014.1 - 0.0048 17.0 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_2 PF13347.6 GAK65015.1 - 1.5e-10 40.3 10.0 2.6e-10 39.5 5.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 GAK65015.1 - 1.4e-09 37.3 13.0 1.4e-09 37.3 13.0 3.1 3 1 0 3 3 3 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 GAK65017.1 - 0.00017 21.9 10.6 0.024 15.1 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK65017.1 - 0.00019 21.7 7.3 0.002 18.5 1.3 2.7 2 0 0 2 2 2 2 Zinc-finger double domain FOXP-CC PF16159.5 GAK65017.1 - 0.036 14.7 2.1 3.9 8.2 0.1 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAK65017.1 - 1.8 9.7 7.1 17 6.6 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.12 GAK65017.1 - 3.2 8.5 5.2 32 5.3 1.8 2.5 1 1 1 2 2 2 0 CHORD Aminotran_5 PF00266.19 GAK65018.1 - 1.6e-33 116.2 0.3 2.4e-26 92.6 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAK65018.1 - 2.4e-05 23.1 0.1 7.8e-05 21.4 0.0 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme zf-Di19 PF05605.12 GAK65019.1 - 0.0015 18.8 2.4 0.0023 18.2 2.4 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.7 GAK65019.1 - 0.0046 17.1 3.9 0.0046 17.1 3.9 1.8 2 1 0 2 2 2 1 Zinc-binding zf_C2H2_ZHX PF18387.1 GAK65019.1 - 0.0059 16.2 0.3 0.0093 15.6 0.3 1.2 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain DUF4749 PF15936.5 GAK65019.1 - 0.097 13.8 0.1 0.11 13.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4749) MDM31_MDM32 PF08118.11 GAK65020.1 - 3.8e-189 629.7 0.0 7.3e-189 628.8 0.0 1.4 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M24 PF00557.24 GAK65021.1 - 2.2e-43 148.4 0.0 3e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 GAK65021.1 - 3.4e-41 141.0 0.0 5.7e-40 137.1 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 GAK65021.1 - 2e-16 59.8 0.1 4.9e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAK65021.1 - 3.4e-15 56.8 0.3 1.2e-13 51.8 0.0 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Pirin_C_2 PF17954.1 GAK65021.1 - 0.071 13.3 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Quercetinase C-terminal cupin domain Glyoxal_oxid_N PF07250.11 GAK65023.1 - 2.7e-28 98.8 1.1 6.3e-15 55.0 0.1 5.0 3 2 2 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAK65023.1 - 7.4e-20 71.1 0.4 1.7e-19 69.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PhosphMutase PF10143.9 GAK65024.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Ribosomal_L11_N PF03946.14 GAK65025.1 - 2.4e-24 85.0 0.1 3.7e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GAK65025.1 - 2.2e-17 63.3 0.5 3.7e-17 62.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.8 GAK65025.1 - 0.0085 16.3 0.8 0.015 15.5 0.8 1.3 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M Thymidylat_synt PF00303.19 GAK65026.1 - 2.3e-109 364.7 0.0 3.9e-109 363.9 0.0 1.4 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 GAK65026.1 - 1.3e-37 129.4 0.1 4.5e-37 127.6 0.1 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Sec23_trunk PF04811.15 GAK65027.1 - 1.3e-58 198.5 0.0 3.8e-58 196.9 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAK65027.1 - 8.9e-23 80.1 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAK65027.1 - 1.5e-19 70.5 0.0 3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAK65027.1 - 2.3e-16 59.6 2.8 4.4e-16 58.6 2.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAK65027.1 - 0.0021 18.0 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat peroxidase PF00141.23 GAK65028.1 - 4.1e-46 157.5 0.0 6.8e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase IGPS PF00218.21 GAK65029.1 - 1.8e-89 299.3 0.0 1e-88 296.8 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 GAK65029.1 - 1e-44 152.6 0.0 4.6e-37 127.7 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 GAK65029.1 - 8.3e-42 143.1 0.0 1.3e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAK65029.1 - 1.3e-05 25.1 0.1 4.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 GAK65029.1 - 0.005 16.6 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 GAK65029.1 - 0.0053 16.0 0.1 2.6 7.2 0.0 2.6 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 GAK65029.1 - 0.15 11.1 5.6 0.16 10.9 0.2 3.1 4 0 0 4 4 4 0 FMN-dependent dehydrogenase HEAT PF02985.22 GAK65030.1 - 4.6e-19 66.9 19.0 0.00012 22.0 0.0 11.2 12 0 0 12 12 11 4 HEAT repeat HEAT_EZ PF13513.6 GAK65030.1 - 9.3e-15 54.8 20.0 2.6e-09 37.4 0.0 8.4 8 2 2 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.6 GAK65030.1 - 1.6e-10 41.2 15.5 0.0013 19.1 0.1 6.8 3 2 5 8 8 8 6 HEAT repeats IBN_N PF03810.19 GAK65030.1 - 1.2e-08 34.7 0.5 6.4e-07 29.2 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 GAK65030.1 - 1.4e-07 31.3 9.4 0.015 15.4 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GAK65030.1 - 0.0004 20.5 0.0 0.0045 17.0 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAK65030.1 - 0.0046 15.6 0.3 0.2 10.2 0.0 3.3 3 2 1 4 4 4 1 Adaptin N terminal region RIX1 PF08167.12 GAK65030.1 - 0.01 15.6 2.1 7.2 6.3 0.0 4.2 5 1 0 6 6 6 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 GAK65030.1 - 0.018 15.7 4.6 30 5.7 0.0 5.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TIP120 PF08623.10 GAK65030.1 - 0.046 13.5 0.8 1.1 9.0 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 GAK65030.1 - 0.047 13.2 0.1 42 3.6 0.0 3.9 4 1 1 5 5 5 0 CLASP N terminal Xpo1 PF08389.12 GAK65030.1 - 0.17 11.9 0.1 20 5.2 0.0 3.8 4 0 0 4 4 4 0 Exportin 1-like protein Sugar_tr PF00083.24 GAK65031.1 - 1e-77 261.9 11.8 1.3e-77 261.6 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK65031.1 - 7.3e-20 71.2 14.2 7.3e-20 71.2 14.2 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily 7tm_2 PF00002.24 GAK65031.1 - 2.4 7.4 7.8 0.2 10.9 0.7 2.5 3 0 0 3 3 3 0 7 transmembrane receptor (Secretin family) CBP4 PF07960.11 GAK65032.1 - 2.2e-12 46.9 0.0 2.7e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 GAK65032.1 - 0.042 13.8 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Pantoate_ligase PF02569.15 GAK65033.1 - 1.3e-88 296.7 0.0 1.8e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UPF0139 PF03669.13 GAK65034.1 - 0.00026 20.8 0.0 0.00042 20.1 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) STE3 PF02076.15 GAK65036.1 - 3.1e-42 144.8 13.2 9.8e-41 139.8 5.7 2.9 1 1 1 2 2 2 2 Pheromone A receptor UL2 PF08196.11 GAK65036.1 - 0.073 13.0 0.0 0.58 10.2 0.1 2.5 3 0 0 3 3 3 0 UL2 protein Stealth_CR2 PF11380.8 GAK65037.1 - 2.7e-16 59.7 0.0 1.8e-09 37.7 0.0 3.0 3 0 0 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 GAK65037.1 - 2.2e-05 24.2 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 GAK65037.1 - 0.0062 16.4 1.1 0.021 14.7 0.1 2.5 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 GAK65037.1 - 0.11 12.3 0.4 0.25 11.1 0.4 1.7 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 Sen15 PF09631.10 GAK65038.1 - 2.8e-12 46.8 0.0 5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein Polysacc_deac_1 PF01522.21 GAK65039.1 - 1.5e-05 24.9 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DAHP_synth_1 PF00793.20 GAK65040.1 - 4.9e-99 330.7 0.0 5.7e-99 330.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_S19 PF00203.21 GAK65041.1 - 4.1e-26 90.7 0.0 5.1e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 OPT PF03169.15 GAK65042.1 - 6.6e-149 497.4 42.9 7.6e-149 497.2 42.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein P16-Arc PF04699.14 GAK65044.1 - 4.3e-46 157.1 0.0 4.8e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF1296 PF06972.11 GAK65044.1 - 0.061 13.5 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Fungal_trans PF04082.18 GAK65045.1 - 1.1e-11 44.3 0.0 1.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65045.1 - 3.4e-06 27.1 8.8 6e-06 26.3 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3-PAP PF12578.8 GAK65045.1 - 0.039 13.7 0.1 0.096 12.4 0.1 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein ArfGap PF01412.18 GAK65052.1 - 1.3e-35 122.0 0.6 2.7e-35 121.0 0.6 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 GAK65052.1 - 1.5e-10 41.5 0.0 3.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 GAK65052.1 - 0.004 16.9 1.2 0.0083 15.9 1.2 1.6 1 0 0 1 1 1 1 BAR domain of APPL family tRNA-synt_1c PF00749.21 GAK65053.1 - 1.7e-78 263.7 0.0 2.3e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Rft-1 PF04506.13 GAK65054.1 - 8.7e-109 364.6 1.2 5.9e-108 361.8 1.2 1.8 1 1 0 1 1 1 1 Rft protein SR-25 PF10500.9 GAK65057.1 - 0.037 13.6 7.6 0.053 13.1 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Kelch_5 PF13854.6 GAK65058.1 - 2.9e-15 55.8 0.1 0.00056 19.8 0.0 5.9 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAK65058.1 - 6.8e-12 45.2 2.9 0.00035 20.5 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAK65058.1 - 1.5e-10 41.1 5.5 0.17 12.2 0.2 5.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAK65058.1 - 2.6e-06 26.9 0.0 0.25 10.9 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 GAK65058.1 - 1.3e-05 25.3 0.9 1.5 9.2 0.0 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAK65058.1 - 0.01 15.8 0.0 0.17 11.9 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Gram_pos_anchor PF00746.21 GAK65058.1 - 0.078 12.9 0.6 0.26 11.3 0.6 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_M3 PF01432.20 GAK65059.1 - 4.6e-119 398.7 0.0 6.3e-119 398.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 PhoLip_ATPase_C PF16212.5 GAK65060.1 - 8.2e-51 173.1 20.5 8.2e-51 173.1 20.5 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAK65060.1 - 1.8e-18 66.0 3.4 4.3e-18 64.8 3.4 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAK65060.1 - 5e-14 53.1 0.3 2.6e-08 34.4 0.2 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAK65060.1 - 3.7e-09 36.5 0.0 1.1e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAK65060.1 - 8.8e-09 35.1 11.2 0.00014 21.4 0.1 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 GAK65060.1 - 0.0098 15.6 0.1 0.022 14.5 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Complex1_LYR_2 PF13233.6 GAK65061.1 - 2.5e-05 24.9 0.0 3.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAK65061.1 - 3e-05 24.0 0.2 5.7e-05 23.1 0.2 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) zf-C2H2_2 PF12756.7 GAK65063.1 - 2.3e-34 117.7 5.2 1.2e-27 96.2 0.0 3.3 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAK65063.1 - 6.5e-12 45.4 16.6 1.1e-09 38.3 2.9 4.5 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAK65063.1 - 7e-10 39.0 4.9 5.9e-09 36.0 2.5 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAK65063.1 - 6.3e-05 23.5 11.3 0.2 12.6 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-DBF PF07535.12 GAK65063.1 - 0.021 14.9 3.6 0.029 14.5 0.6 2.5 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2 PF00096.26 GAK65063.1 - 0.035 14.6 17.2 0.26 11.8 0.3 4.3 4 1 0 4 4 4 0 Zinc finger, C2H2 type DUF5114 PF17141.4 GAK65063.1 - 0.078 13.5 0.1 0.73 10.4 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5114) zf-H2C2_2 PF13465.6 GAK65063.1 - 0.24 11.9 6.8 11 6.7 0.7 3.8 3 0 0 3 3 3 0 Zinc-finger double domain ubiquitin PF00240.23 GAK65064.1 - 1.5e-34 117.6 0.5 1.9e-34 117.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GAK65064.1 - 2.4e-30 104.2 9.4 3.6e-30 103.6 9.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GAK65064.1 - 3.2e-16 58.9 0.6 4.5e-16 58.4 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAK65064.1 - 2.1e-05 24.9 0.1 7.7e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAK65064.1 - 0.0049 16.8 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAK65064.1 - 0.0056 17.0 0.0 0.0084 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAK65064.1 - 0.008 16.3 0.0 0.019 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GAK65064.1 - 0.014 15.4 1.1 4 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 GAK65064.1 - 0.029 14.9 0.0 0.037 14.6 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain EF1G PF00647.19 GAK65065.1 - 4.9e-45 152.0 0.0 8.5e-45 151.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 GAK65065.1 - 1.3e-16 60.7 0.0 5.8e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain CPDase PF07823.11 GAK65065.1 - 1.1e-14 54.7 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein GST_C PF00043.25 GAK65065.1 - 1.4e-11 44.5 0.0 3.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAK65065.1 - 1e-08 35.5 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK65065.1 - 9.1e-08 32.0 0.0 2.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAK65065.1 - 2e-06 27.9 0.1 8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAK65065.1 - 0.00011 22.4 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain 2_5_RNA_ligase2 PF13563.6 GAK65065.1 - 0.017 15.1 0.4 0.082 12.8 0.3 2.0 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Thioredoxin PF00085.20 GAK65066.1 - 2e-60 201.2 0.5 1.2e-30 105.5 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 GAK65066.1 - 6.3e-34 117.5 0.5 2.2e-25 89.6 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.17 GAK65066.1 - 1.2e-09 37.7 0.9 2.1e-09 36.9 0.9 1.2 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 GAK65066.1 - 2.4e-08 34.4 0.9 0.054 14.0 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAK65066.1 - 3.5e-08 33.7 0.1 0.024 14.9 0.0 4.5 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 GAK65066.1 - 5.5e-07 29.2 0.1 0.033 13.6 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GAK65066.1 - 1e-06 28.8 0.0 0.034 14.3 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 GAK65066.1 - 1.6e-06 28.0 0.0 0.1 12.5 0.0 2.8 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.6 GAK65066.1 - 0.00014 22.0 1.4 0.64 10.2 0.1 3.1 3 1 0 3 3 3 2 Thioredoxin Redoxin PF08534.10 GAK65066.1 - 0.0023 17.7 2.1 0.2 11.4 0.0 2.9 3 0 0 3 3 3 1 Redoxin TraF PF13728.6 GAK65066.1 - 0.01 15.7 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 GAK65066.1 - 0.024 14.7 0.0 0.7 10.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain ANAPC1 PF12859.7 GAK65067.1 - 5.6e-17 62.5 0.2 5.6e-17 62.5 0.2 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 APC1_C PF18122.1 GAK65067.1 - 1.5e-12 47.8 0.4 3.6e-12 46.6 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 GAK65067.1 - 1.9e-09 37.5 14.0 0.73 10.4 0.0 6.4 6 0 0 6 6 6 5 Proteasome/cyclosome repeat UQ_con PF00179.26 GAK65068.1 - 1.9e-45 153.9 0.0 2.6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAK65068.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B CAF1 PF04857.20 GAK65069.1 - 1.8e-21 76.6 0.0 1.4e-10 40.9 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease VWA_2 PF13519.6 GAK65070.1 - 2.4e-26 92.5 0.1 9.6e-26 90.5 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 GAK65070.1 - 2.8e-10 40.3 0.0 4.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 GAK65070.1 - 3.5e-10 40.4 0.1 6.9e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 GAK65070.1 - 1.9e-07 30.5 30.5 9.2e-05 22.1 4.0 4.6 5 0 0 5 5 5 3 Ubiquitin interaction motif YjeF_N PF03853.15 GAK65070.1 - 0.019 14.8 1.0 0.041 13.8 0.1 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus RAP80_UIM PF18282.1 GAK65070.1 - 0.54 10.1 11.4 1.6 8.5 0.0 3.5 4 0 0 4 4 4 0 RAP80 N-terminal ubiquitin interaction motif zf-RanBP PF00641.18 GAK65071.1 - 0.00045 19.5 3.0 0.00088 18.5 3.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 GAK65071.1 - 0.4 10.6 4.7 0.98 9.4 4.7 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RhoGEF PF00621.20 GAK65072.1 - 4.2e-39 134.7 0.2 4.2e-39 134.7 0.2 1.6 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 GAK65072.1 - 1.1e-38 132.2 0.0 2.2e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 GAK65072.1 - 2.8e-34 117.2 0.0 5.2e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 GAK65072.1 - 3.8e-08 33.1 0.0 9.7e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 PB1 domain CH PF00307.31 GAK65072.1 - 0.0066 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain AAA PF00004.29 GAK65074.1 - 3.1e-61 205.6 0.0 1e-44 152.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAK65074.1 - 2.6e-09 37.7 7.8 0.008 16.6 0.0 5.8 6 1 0 6 6 5 2 AAA ATPase domain AAA_lid_3 PF17862.1 GAK65074.1 - 2.9e-07 30.2 2.7 0.0042 16.9 0.1 3.4 3 0 0 3 3 3 2 AAA+ lid domain AAA_5 PF07728.14 GAK65074.1 - 1.6e-06 28.1 0.1 0.03 14.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAK65074.1 - 1.3e-05 25.1 0.0 0.0051 16.6 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAK65074.1 - 1.3e-05 25.7 0.0 0.032 14.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 GAK65074.1 - 3.6e-05 24.0 0.2 0.037 14.3 0.1 4.0 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 GAK65074.1 - 6.3e-05 23.2 0.0 0.43 10.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 GAK65074.1 - 0.00011 22.2 0.1 0.24 11.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 GAK65074.1 - 0.00058 19.9 0.0 0.58 10.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 GAK65074.1 - 0.00096 18.9 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.13 GAK65074.1 - 0.00099 18.4 0.0 0.039 13.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Vps4_C PF09336.10 GAK65074.1 - 0.0012 18.8 0.0 0.016 15.2 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain SKI PF01202.22 GAK65074.1 - 0.0014 18.8 1.1 0.057 13.5 0.0 2.9 3 0 0 3 3 2 1 Shikimate kinase AAA_25 PF13481.6 GAK65074.1 - 0.0015 18.2 0.2 0.015 14.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 GAK65074.1 - 0.0018 18.4 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 GAK65074.1 - 0.0019 17.4 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 GAK65074.1 - 0.0022 17.4 0.1 0.056 12.8 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAK65074.1 - 0.0023 17.7 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 GAK65074.1 - 0.0024 17.2 0.1 0.0066 15.8 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_2 PF07724.14 GAK65074.1 - 0.0031 17.6 0.0 0.019 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 GAK65074.1 - 0.0055 16.5 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 NACHT PF05729.12 GAK65074.1 - 0.0055 16.6 0.1 4.1 7.3 0.1 2.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 GAK65074.1 - 0.0061 16.9 0.0 0.095 13.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 GAK65074.1 - 0.0093 16.2 2.5 0.57 10.4 0.0 3.5 3 1 1 4 4 2 1 AAA domain Parvo_NS1 PF01057.17 GAK65074.1 - 0.0098 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 GAK65074.1 - 0.02 14.7 0.0 0.79 9.6 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAK65074.1 - 0.029 13.9 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 GAK65074.1 - 0.042 13.8 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain PhoH PF02562.16 GAK65074.1 - 0.044 13.2 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 GAK65074.1 - 0.092 12.5 0.1 0.24 11.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 GAK65074.1 - 0.15 11.2 0.0 6.2 5.9 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain RRM_1 PF00076.22 GAK65075.1 - 2.5e-32 110.5 0.0 1.1e-15 57.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK65075.1 - 4.1e-12 46.1 0.0 3.1e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif DUF4446 PF14584.6 GAK65075.1 - 0.065 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) RhoGEF PF00621.20 GAK65078.1 - 1e-36 126.9 0.0 1.5e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 GAK65078.1 - 3.6e-17 62.2 10.1 6.4e-17 61.5 10.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAK65078.1 - 8.1e-07 29.5 0.0 3.3e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 GAK65078.1 - 0.0058 16.5 0.0 0.051 13.4 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 GAK65078.1 - 2.6 8.3 6.6 5.5 7.2 6.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger IFT57 PF10498.9 GAK65079.1 - 0.42 9.5 21.4 0.57 9.1 21.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 GAK65079.1 - 2.8 8.0 34.3 1 9.4 31.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Borrelia_P83 PF05262.11 GAK65079.1 - 3 6.3 29.1 3.6 6.0 29.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.16 GAK65079.1 - 4.4 6.1 5.9 5.2 5.9 5.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fasciclin PF02469.22 GAK65079.1 - 7.5 6.8 10.3 7 6.9 8.6 1.9 2 1 1 3 3 3 0 Fasciclin domain SOBP PF15279.6 GAK65079.1 - 7.6 7.0 18.1 9.9 6.7 18.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Atg14 PF10186.9 GAK65079.1 - 9.4 5.2 20.5 15 4.6 20.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ALMT PF11744.8 GAK65079.1 - 9.9 4.9 19.3 12 4.6 19.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ASF1_hist_chap PF04729.13 GAK65080.1 - 2.3e-68 229.0 0.1 2.8e-68 228.7 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Dus PF01207.17 GAK65081.1 - 3e-43 148.1 0.0 1e-22 80.6 0.0 3.1 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) ZT_dimer PF16916.5 GAK65081.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Zn_clus PF00172.18 GAK65082.1 - 4.4e-09 36.3 11.4 7e-09 35.7 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF-5a PF01287.20 GAK65083.1 - 1.1e-29 102.4 0.3 1.5e-29 101.9 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GAK65083.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain RskA PF10099.9 GAK65083.1 - 6.5 7.0 6.6 62 3.8 6.6 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA HLH PF00010.26 GAK65084.1 - 8.7e-13 48.0 0.2 1.6e-12 47.2 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 GAK65084.1 - 0.0077 16.3 0.4 0.025 14.7 0.4 1.8 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF3450 PF11932.8 GAK65084.1 - 0.031 13.6 0.2 0.08 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EMC1_C PF07774.13 GAK65085.1 - 3e-65 219.9 0.0 7.3e-65 218.6 0.0 1.7 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 GAK65085.1 - 2.3e-10 40.4 5.7 3.1e-07 30.2 0.6 3.9 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 GAK65085.1 - 0.0013 18.6 0.2 14 5.8 0.0 4.6 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 GAK65085.1 - 0.44 11.1 4.5 13 6.4 0.0 5.3 5 0 0 5 5 5 0 PQQ-like domain Zn_clus PF00172.18 GAK65086.1 - 1.1e-08 35.1 10.8 1.9e-08 34.3 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb2_6 PF00562.28 GAK65087.1 - 2.7e-122 408.6 0.1 4.1e-122 408.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAK65087.1 - 2.7e-60 203.4 0.1 3.9e-60 202.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAK65087.1 - 8.4e-36 123.4 0.3 1.6e-35 122.5 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAK65087.1 - 2e-30 105.0 0.2 4.8e-30 103.8 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 GAK65087.1 - 4.2e-26 91.0 3.8 4.3e-26 91.0 1.4 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 GAK65087.1 - 4.6e-20 71.6 0.0 1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 GAK65087.1 - 9.8e-12 45.3 0.9 3e-11 43.7 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 RecR PF02132.15 GAK65087.1 - 0.21 11.2 0.2 0.44 10.1 0.2 1.5 1 0 0 1 1 1 0 RecR protein Metallophos PF00149.28 GAK65088.1 - 9e-36 124.3 0.1 1.4e-35 123.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 GAK65088.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 GAK65088.1 - 0.067 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain TAD2 PF18521.1 GAK65088.1 - 0.21 11.6 1.9 0.25 11.4 0.2 2.0 2 0 0 2 2 2 0 Transactivation domain 2 RrnaAD PF00398.20 GAK65089.1 - 6.3e-60 202.5 0.0 8e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAK65089.1 - 2.5e-06 28.1 0.0 4.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK65089.1 - 0.00015 22.4 0.0 0.00032 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK65089.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAK65089.1 - 0.003 18.3 0.0 0.0062 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAK65089.1 - 0.0054 16.0 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GAK65089.1 - 0.0064 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAK65089.1 - 0.0087 15.4 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 GAK65089.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 GAK65089.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 GAK65089.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 GAK65089.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adaptin_N PF01602.20 GAK65090.1 - 3.2e-141 471.5 4.6 4.1e-141 471.1 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAK65090.1 - 9.6e-63 211.0 0.5 1e-58 197.9 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAK65090.1 - 2.4e-17 63.1 4.3 7.1e-06 26.3 0.1 5.9 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.22 GAK65090.1 - 5.1e-10 38.7 0.7 0.01 16.0 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 GAK65090.1 - 1.2e-05 25.7 1.6 0.12 13.0 0.0 6.5 6 2 1 7 7 7 1 HEAT-like repeat Cnd3 PF12719.7 GAK65090.1 - 0.0011 18.3 0.1 0.21 10.7 0.3 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 GAK65090.1 - 0.0022 17.6 0.1 2.3 7.7 0.0 2.9 3 0 0 3 3 3 2 CLASP N terminal Sec7_N PF12783.7 GAK65090.1 - 0.021 14.7 0.5 0.12 12.2 0.1 2.3 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Lyase_1 PF00206.20 GAK65091.1 - 2.7e-23 82.9 0.0 4.2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 GAK65091.1 - 3.9e-18 65.8 0.1 1.1e-17 64.3 0.1 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Adaptin_binding PF10199.9 GAK65092.1 - 5.4e-20 72.2 0.0 1.3e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Sod_Fe_C PF02777.18 GAK65093.1 - 4.3e-35 119.9 0.1 7e-35 119.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAK65093.1 - 1.2e-31 109.0 4.1 1.4e-31 108.8 2.8 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Mus7 PF09462.10 GAK65094.1 - 8.2e-155 517.1 0.0 1.1e-154 516.7 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Syntaxin-6_N PF09177.11 GAK65095.1 - 0.027 15.0 0.7 0.11 13.0 0.0 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4140 PF13600.6 GAK65095.1 - 0.18 12.3 2.4 2.5 8.6 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Membr_traf_MHD PF10540.9 GAK65096.1 - 4e-15 56.3 1.3 4.1e-07 30.3 0.5 2.9 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 GAK65096.1 - 5.1e-10 39.6 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 GAK65096.1 - 1.3e-05 24.0 1.7 1.4e-05 23.9 0.4 1.7 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) 60KD_IMP PF02096.20 GAK65098.1 - 5.2e-28 98.0 0.3 7.5e-28 97.5 0.3 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein ApoLp-III PF07464.11 GAK65098.1 - 0.0095 16.0 4.0 0.019 15.1 3.0 1.9 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Myb_DNA-bind_4 PF13837.6 GAK65099.1 - 0.12 12.7 2.3 0.27 11.6 0.5 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 GAK65099.1 - 0.14 12.5 0.4 0.66 10.3 0.4 2.2 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Aa_trans PF01490.18 GAK65100.1 - 6.4e-20 71.2 33.4 8.1e-20 70.9 33.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein F-box-like PF12937.7 GAK65101.1 - 6.7e-11 41.9 0.1 1.5e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF3506 PF12014.8 GAK65101.1 - 1.8e-10 40.9 0.0 5.7e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 GAK65101.1 - 0.00036 20.3 0.0 0.00098 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAK65101.1 - 0.00038 20.3 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 F-box WD40 PF00400.32 GAK65102.1 - 2.6e-14 53.4 2.0 0.01 16.7 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat VHS PF00790.19 GAK65103.1 - 1.5e-14 54.0 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 VHS domain IFRD PF05004.13 GAK65103.1 - 0.007 15.5 1.0 0.035 13.2 0.0 2.3 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Ras PF00071.22 GAK65104.1 - 5.1e-59 198.5 0.0 6e-59 198.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK65104.1 - 2.1e-35 121.5 0.0 3.4e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK65104.1 - 3.1e-12 46.3 0.0 3.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK65104.1 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK65104.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAK65104.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAK65104.1 - 4.3e-05 23.5 0.7 0.28 11.1 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 GAK65104.1 - 0.0071 16.8 1.0 0.035 14.5 1.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 GAK65104.1 - 0.0087 15.5 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 GAK65104.1 - 0.026 14.8 0.1 2.4 8.4 0.0 2.5 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 GAK65104.1 - 0.14 11.5 0.1 0.57 9.6 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NIF3 PF01784.18 GAK65105.1 - 5.5e-65 219.4 0.0 7.1e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COPIIcoated_ERV PF07970.12 GAK65106.1 - 1.9e-36 126.0 0.1 3.8e-36 125.0 0.1 1.5 1 1 1 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAK65106.1 - 2.9e-26 91.6 0.1 5.2e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CST-I PF06002.12 GAK65106.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) RNA_pol_A_bac PF01000.26 GAK65107.1 - 4.3e-28 97.9 0.0 7.7e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAK65107.1 - 1.3e-20 72.6 0.0 2.1e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4775 PF16001.5 GAK65107.1 - 0.005 16.3 0.6 0.0071 15.8 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4775) Peptidase_C65 PF10275.9 GAK65108.1 - 2e-76 256.7 0.0 2.4e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 GAK65108.1 - 0.044 14.3 0.0 2.1 8.8 0.0 2.3 1 1 0 1 1 1 0 OTU-like cysteine protease Fungal_trans PF04082.18 GAK65109.1 - 1.5e-11 43.9 0.3 2.8e-11 43.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65109.1 - 4.3e-05 23.5 11.0 6.7e-05 22.9 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 GAK65109.1 - 0.97 9.4 41.1 11 5.9 42.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pyr_redox_2 PF07992.14 GAK65110.1 - 3.1e-65 220.3 6.5 3.1e-65 220.3 6.5 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAK65110.1 - 5.3e-42 142.5 2.4 6.2e-42 142.3 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAK65110.1 - 1.1e-18 67.5 8.4 9.2e-16 58.2 2.0 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAK65110.1 - 1e-10 41.6 0.3 1e-10 41.6 0.3 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAK65110.1 - 1e-10 41.4 6.0 9.7e-08 31.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAK65110.1 - 2.4e-08 33.5 8.4 1e-06 28.1 3.9 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAK65110.1 - 2.1e-07 31.1 4.4 0.00013 22.1 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAK65110.1 - 4.2e-07 29.4 1.9 4.2e-07 29.4 1.9 3.6 3 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.14 GAK65110.1 - 2e-06 26.8 12.9 0.00063 18.6 0.8 4.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 GAK65110.1 - 3.2e-06 26.6 3.7 0.0018 17.5 0.1 2.4 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.21 GAK65110.1 - 4.4e-06 26.1 3.5 0.012 14.9 0.4 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 GAK65110.1 - 8e-06 25.2 0.4 0.15 11.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 GAK65110.1 - 2e-05 24.0 9.0 0.064 12.5 0.1 3.3 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 GAK65110.1 - 0.022 14.3 13.3 0.57 9.7 0.1 3.9 3 1 0 4 4 4 0 FAD dependent oxidoreductase Mqo PF06039.15 GAK65110.1 - 0.069 11.7 2.0 0.17 10.4 0.2 2.0 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 GAK65110.1 - 0.32 10.0 3.2 1.2 8.1 0.1 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.18 GAK65110.1 - 2.9 7.7 6.8 0.23 11.3 1.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GluRS_N PF18466.1 GAK65110.1 - 3.3 8.2 6.7 7 7.1 0.5 3.3 4 0 0 4 4 4 0 Glutamate--tRNA ligase N-terminal domain UQ_con PF00179.26 GAK65113.1 - 3e-35 120.9 0.0 3.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L18A PF01775.17 GAK65114.1 - 1.6e-51 173.4 1.3 2e-51 173.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PWI PF01480.17 GAK65116.1 - 2.2e-09 37.5 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 GAK65116.1 - 1.4e-07 31.4 0.0 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 GAK65116.1 - 2e-06 27.5 4.6 3.5e-06 26.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK65116.1 - 9.9e-05 22.3 6.8 0.00018 21.4 6.8 1.5 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 GAK65116.1 - 0.0002 21.1 0.1 0.45 10.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 GAK65116.1 - 0.016 15.0 4.5 0.028 14.2 4.5 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Torus PF16131.5 GAK65116.1 - 0.021 15.5 0.1 0.048 14.3 0.1 1.6 1 0 0 1 1 1 0 Torus domain Seryl_tRNA_N PF02403.22 GAK65116.1 - 0.26 11.5 12.4 0.042 14.1 5.2 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-CCCH_2 PF14608.6 GAK65116.1 - 4.6 7.9 5.6 8 7.1 5.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger COX5A PF02284.16 GAK65117.1 - 1.4e-40 137.4 0.1 2.4e-40 136.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Adap_comp_sub PF00928.21 GAK65118.1 - 3e-22 79.3 0.0 4e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAK65118.1 - 3.1e-05 23.9 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TT_ORF2 PF02957.15 GAK65118.1 - 0.23 12.4 1.0 0.42 11.5 0.2 1.8 1 1 1 2 2 2 0 TT viral ORF2 MreC PF04085.14 GAK65119.1 - 0.071 13.0 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 rod shape-determining protein MreC RRM_1 PF00076.22 GAK65121.1 - 1.7e-18 66.2 0.3 2.4e-09 36.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK65121.1 - 0.00041 20.0 0.0 0.39 10.3 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAK65121.1 - 0.0081 16.1 0.2 0.63 10.1 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 GAK65121.1 - 0.13 12.1 0.0 0.94 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_1 PF00076.22 GAK65123.1 - 6.1e-22 77.2 0.0 8.7e-22 76.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK65123.1 - 0.0069 16.0 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1302 PF06980.11 GAK65123.1 - 0.047 12.3 0.3 0.056 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) RRM_occluded PF16842.5 GAK65123.1 - 0.049 13.5 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 GAK65123.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif GRP PF07172.11 GAK65123.1 - 5.2 7.8 10.8 12 6.7 10.8 1.6 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.22 GAK65124.1 - 1.3e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAK65124.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SET PF00856.28 GAK65125.1 - 2e-14 54.3 0.0 4.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 SET domain TackOD1 PF18551.1 GAK65125.1 - 4.1 7.0 10.0 0.16 11.7 0.6 2.4 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 NST1 PF13945.6 GAK65126.1 - 5.7e-49 166.8 6.4 5.7e-49 166.8 6.4 5.3 3 2 1 4 4 4 2 Salt tolerance down-regulator BRF1 PF07741.13 GAK65126.1 - 0.54 10.6 0.0 0.54 10.6 0.0 7.0 4 1 0 4 4 4 0 Brf1-like TBP-binding domain Mid1 PF12929.7 GAK65129.1 - 2.4e-73 247.8 1.9 3.3e-73 247.3 1.9 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 GAK65129.1 - 0.0073 16.9 4.5 0.021 15.4 0.7 2.5 2 0 0 2 2 2 1 Fz domain DM13 PF10517.9 GAK65129.1 - 0.11 13.1 0.1 14 6.3 0.0 2.5 2 0 0 2 2 2 0 Electron transfer DM13 fn3 PF00041.21 GAK65129.1 - 0.21 11.9 1.6 0.45 10.9 0.0 2.2 2 1 0 2 2 2 0 Fibronectin type III domain ABC1 PF03109.16 GAK65130.1 - 1.3e-28 99.5 0.0 2.4e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.9 GAK65130.1 - 2.9e-18 65.2 0.4 2.9e-18 65.2 0.4 2.3 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Pkinase PF00069.25 GAK65130.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF5522 PF17653.1 GAK65130.1 - 0.21 11.6 4.0 0.44 10.5 4.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Lipase_3 PF01764.25 GAK65131.1 - 1.2e-14 54.4 0.0 2.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 GAK65131.1 - 0.00034 20.3 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK65131.1 - 0.13 12.9 1.1 0.24 12.0 0.2 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family zf-CCHC_2 PF13696.6 GAK65132.1 - 0.04 13.8 1.8 0.04 13.8 1.8 1.9 2 0 0 2 2 2 0 Zinc knuckle Lactococcin_972 PF09683.10 GAK65132.1 - 0.91 10.1 3.2 0.57 10.8 0.2 2.0 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) MFS_1 PF07690.16 GAK65133.1 - 8e-26 90.8 43.6 8e-26 90.8 43.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 GAK65133.1 - 0.00099 17.5 4.3 0.028 12.7 0.5 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family SR-25 PF10500.9 GAK65133.1 - 1.2 8.7 3.9 1.9 8.0 3.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gp_dh_C PF02800.20 GAK65134.1 - 3.8e-72 241.0 0.0 5.6e-72 240.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAK65134.1 - 9e-34 115.9 0.0 2.2e-33 114.6 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TauD PF02668.16 GAK65135.1 - 1.8e-25 90.3 3.1 4.5e-25 88.9 3.1 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RNA_pol PF00940.19 GAK65136.1 - 4.7e-175 582.4 0.0 7.1e-175 581.8 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GAK65136.1 - 2.9e-98 329.4 4.5 2.9e-98 329.4 4.5 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 GAK65136.1 - 0.00075 19.6 0.0 0.11 12.7 0.0 3.2 2 1 0 2 2 2 1 PPR repeat family SpoU_sub_bind PF08032.12 GAK65136.1 - 0.033 14.4 0.2 0.14 12.4 0.2 2.1 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Ras PF00071.22 GAK65137.1 - 1.8e-50 170.7 0.0 2.1e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK65137.1 - 3.7e-23 82.0 0.0 6.7e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK65137.1 - 4.3e-06 26.3 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAK65137.1 - 0.023 14.3 0.0 0.053 13.0 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAK65137.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 GAK65137.1 - 0.094 12.5 0.0 10 5.9 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAK65137.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PCI PF01399.27 GAK65138.1 - 2e-10 41.1 0.0 5.8e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain Amidohydro_3 PF07969.11 GAK65139.1 - 1.4e-75 255.6 2.6 1.9e-75 255.2 2.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAK65139.1 - 3.1e-09 36.6 0.0 1.5e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Methyltransf_31 PF13847.6 GAK65139.1 - 7.7e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK65139.1 - 1.6e-07 31.3 0.0 6e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK65139.1 - 3.2e-07 31.0 0.0 7.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK65139.1 - 4.1e-07 30.7 0.0 7.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK65139.1 - 8.8e-06 26.3 0.0 2.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK65139.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAK65139.1 - 0.0036 16.6 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 GAK65139.1 - 0.0045 18.0 0.0 0.017 16.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAK65139.1 - 0.057 13.2 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase FA_desaturase PF00487.24 GAK65141.1 - 1.3e-23 84.1 27.6 3.5e-23 82.8 27.6 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAK65141.1 - 2.1e-12 47.0 0.0 4.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CX9C PF16860.5 GAK65142.1 - 1.1e-06 28.5 2.7 0.018 15.0 0.3 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 GAK65142.1 - 0.00075 19.7 2.3 0.0067 16.7 2.2 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) NDUF_B7 PF05676.13 GAK65142.1 - 0.04 13.6 1.0 1.5 8.6 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 GAK65142.1 - 0.059 13.5 2.1 0.46 10.7 1.8 2.0 1 1 1 2 2 2 0 CHCH domain NTP_transf_7 PF07984.12 GAK65142.1 - 0.11 11.7 0.1 0.13 11.5 0.1 1.0 1 0 0 1 1 1 0 Nucleotidyltransferase Abhydrolase_1 PF00561.20 GAK65143.1 - 7.5e-09 35.6 0.0 2.8e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK65143.1 - 0.018 14.3 0.0 5.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pan3_PK PF18101.1 GAK65144.1 - 8.8e-64 213.6 0.1 1.4e-63 213.0 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 GAK65144.1 - 0.37 10.1 1.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Plasmodium_Vir PF05795.11 GAK65144.1 - 0.52 9.7 1.2 0.87 8.9 1.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SRI PF08236.11 GAK65145.1 - 2e-21 75.9 1.6 4.4e-21 74.9 1.6 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 GAK65145.1 - 1.8e-19 70.8 0.1 1.8e-19 70.8 0.1 2.7 2 2 0 2 2 2 1 SET domain AWS PF17907.1 GAK65145.1 - 1.3e-11 44.4 5.2 1.3e-11 44.4 5.2 2.2 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 GAK65145.1 - 2.4 8.2 4.4 0.88 9.6 0.1 2.6 3 0 0 3 3 3 0 TFIIS helical bundle-like domain Macoilin PF09726.9 GAK65145.1 - 3.8 6.0 12.1 6.2 5.3 12.1 1.3 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 GAK65146.1 - 5.1e-10 39.8 2.1 0.00059 20.6 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK65146.1 - 9.7e-10 38.6 0.0 0.014 15.7 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK65146.1 - 0.0033 16.4 0.4 0.012 14.6 0.0 2.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAK65146.1 - 0.0096 15.8 1.3 0.19 11.7 0.0 3.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 GAK65146.1 - 0.031 13.6 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal IPTL-CTERM PF18203.1 GAK65146.1 - 0.13 12.1 0.3 0.28 11.1 0.3 1.6 1 0 0 1 1 1 0 IPTL-CTERM motif DUF1206 PF06724.11 GAK65146.1 - 0.4 10.8 2.8 0.33 11.1 0.6 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) MFS_1 PF07690.16 GAK65147.1 - 3.3e-18 65.7 32.7 3.3e-18 65.7 32.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAK65147.1 - 2.4e-14 53.4 8.0 5.7e-14 52.1 8.0 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Abhydrolase_3 PF07859.13 GAK65148.1 - 1.2e-47 162.6 0.0 1.5e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAK65148.1 - 7.4e-07 28.4 1.6 4.7e-06 25.8 1.6 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAK65148.1 - 0.00023 20.7 0.6 0.0041 16.6 0.7 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 GAK65148.1 - 0.0064 15.2 0.3 0.052 12.2 0.3 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 GAK65148.1 - 0.014 14.7 0.3 0.045 13.0 0.0 2.0 3 1 0 3 3 3 0 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 GAK65148.1 - 0.016 14.7 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region HsbA PF12296.8 GAK65149.1 - 4.5e-14 52.9 0.3 8.5e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A BORCS6 PF10157.9 GAK65149.1 - 0.055 13.7 0.2 0.088 13.0 0.2 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF1045 PF06299.12 GAK65149.1 - 0.057 13.4 0.3 0.094 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) DUF4499 PF14934.6 GAK65150.1 - 0.076 13.3 1.1 0.14 12.5 0.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4499) DUF1929 PF09118.11 GAK65151.1 - 4.2e-22 78.3 0.6 1.2e-21 76.7 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.26 GAK65151.1 - 7.8e-17 61.0 24.4 6.4e-06 26.1 1.3 4.4 4 0 0 4 4 4 4 PAN domain Kelch_1 PF01344.25 GAK65151.1 - 3.1e-08 33.0 4.4 0.00016 21.2 0.2 3.8 3 0 0 3 3 3 2 Kelch motif PAN_4 PF14295.6 GAK65151.1 - 1.9e-07 30.9 29.8 0.00092 19.1 1.6 4.8 4 0 0 4 4 4 3 PAN domain Kelch_6 PF13964.6 GAK65151.1 - 3.8e-07 30.2 12.2 0.0002 21.5 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Glyoxal_oxid_N PF07250.11 GAK65151.1 - 2.1e-06 27.1 4.0 0.0025 17.0 0.1 2.8 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 GAK65151.1 - 7.3e-06 25.9 13.4 0.013 15.5 0.3 5.1 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAK65151.1 - 0.0016 18.3 7.0 0.79 9.8 0.0 4.7 4 0 0 4 4 4 2 Kelch motif MANEC PF07502.14 GAK65151.1 - 0.0017 18.5 21.0 0.35 11.2 0.2 4.4 4 0 0 4 4 4 3 MANEC domain EAV_GP5 PF15981.5 GAK65151.1 - 0.71 10.3 3.1 4.7 7.7 0.1 3.2 3 0 0 3 3 3 0 Envelope glycoprotein GP 5 of equine arteritis virus Sugar_tr PF00083.24 GAK65152.1 - 6.8e-107 358.1 24.2 7.9e-107 357.9 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK65152.1 - 4.5e-20 71.9 36.1 1.3e-19 70.3 8.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.22 GAK65153.1 - 2.5e-30 105.2 0.0 3.1e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.18 GAK65154.1 - 6.3e-09 35.8 9.0 1e-08 35.1 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK65154.1 - 0.00069 18.7 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2306 PF10067.9 GAK65155.1 - 8.1e-07 29.4 11.6 7.4e-06 26.2 11.2 2.5 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) ATG22 PF11700.8 GAK65156.1 - 6.8e-45 153.6 16.8 8.6e-45 153.2 16.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Phage_mat-A PF03863.13 GAK65156.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Phage maturation protein DUF4281 PF14108.6 GAK65156.1 - 7.3 7.0 10.9 8 6.8 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4281) PAN_4 PF14295.6 GAK65157.1 - 0.015 15.2 1.2 0.034 14.1 1.2 1.5 1 0 0 1 1 1 0 PAN domain Fungal_trans PF04082.18 GAK65159.1 - 4.2e-19 68.6 0.0 7.7e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65159.1 - 4.4e-09 36.3 11.0 8.4e-09 35.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 GAK65160.1 - 1.1e-10 42.2 0.0 2.6e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAK65160.1 - 7.1e-06 25.0 0.0 0.19 10.4 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 GAK65160.1 - 0.0044 17.4 0.0 0.0095 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.19 GAK65161.1 - 4.8e-19 68.8 0.6 1.3e-18 67.4 0.6 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAK65161.1 - 6.7e-11 42.4 2.0 5.1e-05 23.0 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK65161.1 - 8.9e-08 31.7 0.1 0.0086 15.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAK65161.1 - 3e-06 26.4 0.4 0.011 14.6 0.1 2.6 3 0 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.24 GAK65161.1 - 7.4e-06 25.5 1.9 0.0013 18.1 0.0 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK65161.1 - 5e-05 23.4 0.7 0.00016 21.8 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAK65161.1 - 0.001 17.9 0.7 0.021 13.5 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 GAK65161.1 - 0.0011 18.1 5.8 0.1 11.6 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAK65161.1 - 0.0014 17.8 1.9 0.0014 17.8 1.9 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 GAK65161.1 - 0.011 16.2 0.3 0.91 10.1 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAK65161.1 - 0.028 13.5 0.0 0.068 12.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.7 GAK65161.1 - 0.05 12.9 1.9 0.11 11.8 1.9 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAK65161.1 - 0.054 12.7 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 GAK65161.1 - 0.11 12.1 0.2 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAK65161.1 - 0.14 11.3 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 GAK65162.1 - 2.3e-25 89.3 36.8 6.4e-24 84.5 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAK65162.1 - 2e-07 29.8 5.1 3.5e-07 29.0 5.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAK65162.1 - 9.4e-06 24.7 44.6 0.0019 17.1 44.6 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 GAK65163.1 - 1.2e-88 298.0 15.7 1.4e-88 297.7 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK65163.1 - 1.4e-20 73.5 34.7 3.1e-17 62.5 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAK65163.1 - 5.6e-07 28.5 12.2 0.0012 17.5 1.9 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Alpha-amylase PF00128.24 GAK65165.1 - 6.3e-116 387.6 0.2 1e-115 386.9 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 GAK65165.1 - 0.0003 20.8 0.0 0.00081 19.5 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 GAK65165.1 - 0.00073 18.7 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 GAK65165.1 - 0.0018 18.0 0.1 0.0059 16.3 0.1 1.9 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Alpha-amylase_C PF02806.18 GAK65165.1 - 0.04 14.4 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Gln-synt_C PF00120.24 GAK65166.1 - 5.2e-69 232.9 0.0 1.3e-68 231.5 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Aldedh PF00171.22 GAK65167.1 - 4.9e-127 424.2 0.1 5.5e-127 424.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAK65167.1 - 0.07 12.2 0.2 0.4 9.7 0.0 2.2 2 1 0 2 2 2 0 Acyl-CoA reductase (LuxC) adh_short_C2 PF13561.6 GAK65168.1 - 4e-64 216.4 0.1 5.1e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK65168.1 - 2.4e-45 154.4 0.2 2.9e-45 154.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK65168.1 - 2e-07 31.1 0.4 4e-07 30.1 0.4 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAK65168.1 - 0.00041 20.3 0.2 0.0018 18.2 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OPT PF03169.15 GAK65169.1 - 6.5e-130 434.7 46.7 7.3e-130 434.5 46.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 GAK65169.1 - 1.5 8.1 4.3 0.52 9.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) FAD_binding_3 PF01494.19 GAK65170.1 - 8.5e-21 74.6 0.0 1.2e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAK65170.1 - 3.9e-06 27.0 1.0 1e-05 25.7 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAK65170.1 - 6.4e-06 25.6 0.5 4.6e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAK65170.1 - 0.00016 20.9 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAK65170.1 - 0.00043 20.0 0.1 0.00061 19.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK65170.1 - 0.00054 19.2 2.3 0.0015 17.7 1.7 2.0 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 GAK65170.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAK65170.1 - 0.02 15.4 0.5 0.057 14.0 0.5 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAK65170.1 - 0.048 12.5 0.3 0.35 9.6 0.2 2.2 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.16 GAK65170.1 - 0.053 13.2 1.0 6.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAK65170.1 - 0.12 11.4 3.7 0.09 11.8 1.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAK65170.1 - 0.13 11.5 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAK65170.1 - 0.17 10.5 0.6 0.31 9.7 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.18 GAK65171.1 - 5.7e-08 32.1 1.2 1.1e-07 31.2 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65171.1 - 4.8e-07 29.8 9.6 8.5e-07 29.0 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.11 GAK65172.1 - 2.2e-17 64.0 0.2 4e-17 63.1 0.2 1.4 1 0 0 1 1 1 1 EthD domain COesterase PF00135.28 GAK65173.1 - 9.6e-87 292.0 0.3 1.2e-86 291.6 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK65173.1 - 2.5e-06 27.5 0.7 2e-05 24.6 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAK65173.1 - 0.0043 16.5 0.2 0.0091 15.5 0.2 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 GAK65173.1 - 0.011 14.6 0.0 0.035 13.0 0.0 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase DNA_pol_A_exo1 PF01612.20 GAK65173.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease ELO PF01151.18 GAK65174.1 - 6.8e-57 192.9 17.9 8.1e-57 192.6 17.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CoA_transf_3 PF02515.17 GAK65175.1 - 1.4e-63 215.3 0.0 4.5e-63 213.6 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III GFO_IDH_MocA PF01408.22 GAK65176.1 - 5.5e-17 62.7 0.0 8.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAK65176.1 - 1.1e-05 25.4 0.0 0.00015 21.7 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Zn_clus PF00172.18 GAK65177.1 - 0.00035 20.6 8.3 0.00035 20.6 8.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XLF PF09302.11 GAK65177.1 - 0.076 13.2 0.1 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Sugar_tr PF00083.24 GAK65178.1 - 2.8e-80 270.4 21.3 3.6e-80 270.0 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK65178.1 - 2.7e-20 72.6 36.0 5.5e-18 65.0 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAK65178.1 - 6.2e-08 31.6 16.2 0.00033 19.4 4.7 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein DUF2951 PF11166.8 GAK65178.1 - 0.034 14.4 2.4 8.8 6.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) DUF3007 PF11460.8 GAK65178.1 - 3.2 8.1 5.3 5.8 7.2 2.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) RAI1 PF08652.11 GAK65179.1 - 3.6e-20 71.9 0.0 7.3e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Acetyltransf_1 PF00583.25 GAK65179.1 - 9.3e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3486 PF11985.8 GAK65179.1 - 0.88 10.0 6.2 10 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) UQ_con PF00179.26 GAK65180.1 - 9e-17 61.0 0.0 1.8e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAK65180.1 - 0.077 13.3 0.0 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 RWD domain TPT PF03151.16 GAK65181.1 - 1.7e-52 178.6 13.9 2.7e-52 177.9 13.9 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAK65181.1 - 1e-14 54.9 21.2 1.2e-09 38.4 9.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAK65181.1 - 2.3e-10 40.2 12.4 2.9e-10 39.9 12.4 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 GAK65181.1 - 0.00016 21.0 10.2 0.008 15.4 0.5 2.6 2 1 0 2 2 2 2 Nucleotide-sugar transporter TMEM100 PF16311.5 GAK65181.1 - 0.28 10.8 3.4 2.7 7.6 0.2 2.9 2 1 1 3 3 3 0 Transmembrane protein 100 Multi_Drug_Res PF00893.19 GAK65181.1 - 1.1 9.9 8.6 0.12 13.0 2.9 2.3 2 1 0 2 2 2 0 Small Multidrug Resistance protein MBOAT_2 PF13813.6 GAK65183.1 - 2.3e-05 24.6 1.7 0.0016 18.7 0.5 2.7 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family DUF1129 PF06570.11 GAK65183.1 - 0.91 9.0 6.2 1.8 8.0 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ABC_tran PF00005.27 GAK65184.1 - 5.3e-21 75.6 0.0 2.6e-15 57.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAK65184.1 - 9.4e-09 35.5 0.2 0.025 14.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAK65184.1 - 6.6e-05 23.1 0.0 0.051 13.8 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAK65184.1 - 0.0027 17.4 0.0 0.0075 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK65184.1 - 0.0034 17.8 2.1 0.0086 16.5 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GAK65184.1 - 0.018 14.9 0.1 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 GAK65184.1 - 0.021 14.6 0.0 0.053 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAK65184.1 - 0.097 13.2 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 GAK65184.1 - 0.24 10.5 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 F_bP_aldolase PF01116.20 GAK65185.1 - 1.1e-73 248.1 0.0 1.3e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II WD40 PF00400.32 GAK65186.1 - 1.7e-31 107.7 17.1 4.5e-06 27.3 0.1 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK65186.1 - 6.2e-13 48.9 1.6 0.0027 18.0 0.3 6.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK65186.1 - 1.3e-06 27.6 4.6 0.15 11.0 0.1 4.4 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAK65186.1 - 3.6e-05 23.2 0.5 0.44 9.8 0.0 3.9 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 GAK65186.1 - 0.0033 16.1 0.0 0.022 13.4 0.0 2.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 GAK65186.1 - 0.0037 16.6 0.0 7.4 5.7 0.0 3.5 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 GAK65186.1 - 0.0068 15.2 0.0 0.14 10.8 0.0 2.6 2 0 0 2 2 2 1 Nup133 N terminal like PD40 PF07676.12 GAK65186.1 - 0.017 15.1 0.1 11 6.1 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 GAK65186.1 - 0.028 12.8 0.0 0.073 11.4 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2850 PF11012.8 GAK65186.1 - 0.13 12.6 0.0 0.56 10.5 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) Asp_Glu_race PF01177.22 GAK65188.1 - 7.1e-08 32.6 0.0 2.2e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 GAK65188.1 - 0.02 14.5 0.5 0.05 13.2 0.2 1.8 2 0 0 2 2 2 0 Arylmalonate decarboxylase AroM PF07302.11 GAK65188.1 - 0.056 12.8 0.2 0.33 10.3 0.1 2.0 1 1 1 2 2 2 0 AroM protein FAD_binding_4 PF01565.23 GAK65189.1 - 3.1e-26 91.8 1.6 3.1e-26 91.8 1.6 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAK65189.1 - 4.9e-13 48.9 0.1 9e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like SH3_1 PF00018.28 GAK65189.1 - 0.071 12.7 0.6 0.16 11.6 0.6 1.5 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.17 GAK65189.1 - 0.29 10.9 0.9 1.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Variant SH3 domain COA2 PF17051.5 GAK65190.1 - 0.0015 18.6 0.1 0.0017 18.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 LCCL PF03815.19 GAK65191.1 - 1.4e-16 60.4 0.0 2.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 LCCL domain DUF1308 PF07000.11 GAK65191.1 - 0.00032 20.7 0.2 0.45 10.4 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1308) ADH_N PF08240.12 GAK65192.1 - 8.7e-21 73.9 2.9 1.7e-20 72.9 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK65192.1 - 7e-17 61.6 0.0 1.2e-15 57.6 0.0 2.4 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAK65192.1 - 0.00026 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAK65192.1 - 0.0016 18.6 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 GAK65192.1 - 0.0045 16.6 0.1 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 GAK65192.1 - 0.02 14.2 0.6 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAK65192.1 - 0.024 15.1 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 GAK65192.1 - 0.031 15.1 0.0 1.3 9.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold IGFBP PF00219.18 GAK65192.1 - 0.041 14.5 0.5 0.082 13.6 0.5 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Shikimate_DH PF01488.20 GAK65192.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 GAK65192.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 GAK65193.1 - 2e-17 63.2 72.3 4e-12 45.7 46.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Vac14_Fig4_bd PF11916.8 GAK65193.1 - 0.2 11.3 0.7 0.36 10.5 0.7 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding DUF5345 PF17280.2 GAK65193.1 - 5.7 7.0 5.6 17 5.5 5.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Acetyltransf_10 PF13673.7 GAK65194.1 - 7.8e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK65194.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK65194.1 - 5.1e-05 23.6 0.0 8.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAK65194.1 - 0.044 13.9 0.1 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK65194.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein GET2 PF08690.10 GAK65194.1 - 0.062 13.0 0.2 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 GET complex subunit GET2 zf-C3HC4_3 PF13920.6 GAK65195.1 - 2.9e-06 27.0 8.2 4.9e-06 26.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAK65195.1 - 1.1e-05 25.7 14.2 2.2e-05 24.7 14.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAK65195.1 - 0.00097 19.0 12.1 0.0017 18.2 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK65195.1 - 0.0031 17.3 13.0 0.0059 16.4 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAK65195.1 - 0.016 15.5 8.9 0.032 14.5 8.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAK65195.1 - 4.6 7.3 10.3 8.1 6.5 10.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain dCMP_cyt_deam_1 PF00383.23 GAK65196.1 - 3.8e-08 33.1 0.0 9.9e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAK65196.1 - 3.9e-05 23.4 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Pirin_C PF05726.13 GAK65197.1 - 1.8e-24 86.1 0.1 3.4e-23 82.0 0.0 2.7 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 GAK65197.1 - 1.4e-18 66.9 0.4 3e-18 65.8 0.4 1.5 1 0 0 1 1 1 1 Pirin ECR1_N PF14382.6 GAK65198.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region zf-CCHC_2 PF13696.6 GAK65198.1 - 0.019 14.8 1.5 0.019 14.8 1.5 2.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 GAK65198.1 - 0.1 12.5 0.8 0.34 10.8 0.8 2.0 1 0 0 1 1 1 0 Zinc knuckle Herpes_DNAp_acc PF04929.12 GAK65198.1 - 8.2 5.3 6.9 13 4.7 6.9 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RVT_1 PF00078.27 GAK65199.1 - 1.8e-23 83.2 0.0 3.5e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GAK65199.1 - 0.00023 20.8 0.8 0.00062 19.3 0.8 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 GAK65199.1 - 0.0066 17.1 4.1 0.0066 17.1 4.1 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 GAK65199.1 - 0.05 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Pirin PF02678.16 GAK65200.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Pirin zf-C2H2 PF00096.26 GAK65201.1 - 1.3e-06 28.5 8.4 0.0015 18.9 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK65201.1 - 8.3e-05 23.1 8.2 0.015 16.1 0.7 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK65201.1 - 0.0032 17.8 0.3 0.0032 17.8 0.3 3.2 4 0 0 4 4 4 1 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 GAK65201.1 - 0.01 15.8 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF3493 PF11998.8 GAK65201.1 - 0.013 15.7 0.1 0.029 14.5 0.1 1.6 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 IBR PF01485.21 GAK65201.1 - 0.022 14.9 0.3 0.072 13.3 0.3 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain adh_short PF00106.25 GAK65202.1 - 2.1e-37 128.5 0.0 2.7e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK65202.1 - 2e-27 96.2 0.0 3.1e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAK65202.1 - 5.7e-07 29.2 0.0 7.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAK65202.1 - 6.3e-07 29.5 1.4 9.1e-06 25.7 1.4 2.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAK65202.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAK65202.1 - 0.0014 17.7 0.1 0.0019 17.2 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 GAK65202.1 - 0.0029 17.0 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAK65202.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAK65202.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 GAK65202.1 - 0.082 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 GAK65202.1 - 0.09 13.0 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAK65202.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 GAK65202.1 - 0.21 11.7 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_11 PF08241.12 GAK65205.1 - 5.6e-18 65.4 0.0 1.3e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK65205.1 - 1.2e-15 57.9 0.0 7e-15 55.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK65205.1 - 1.5e-08 35.3 0.0 4.4e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK65205.1 - 4.8e-06 26.5 0.0 1.6e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK65205.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAK65205.1 - 5.3e-05 23.1 0.0 7.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4210 PF13915.6 GAK65206.1 - 2.5e-29 101.6 0.0 5.6e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 GAK65206.1 - 2.3e-19 69.3 0.0 4.5e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis Sulfate_transp PF00916.20 GAK65209.1 - 1.1e-109 366.7 16.8 1.4e-109 366.4 16.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAK65209.1 - 5.2e-10 39.0 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAK65209.1 - 0.001 19.4 10.3 0.0014 19.0 1.4 3.0 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Wzt_C PF14524.6 GAK65210.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Wzt C-terminal domain DUF2810 PF10928.8 GAK65211.1 - 0.18 11.8 0.1 0.33 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Ion_trans_2 PF07885.16 GAK65214.1 - 8.8e-32 108.9 28.7 1.9e-16 59.8 9.0 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 GAK65214.1 - 7.6e-07 28.6 8.8 0.00014 21.2 0.6 2.4 2 0 0 2 2 2 2 Ion transport protein Ctr PF04145.15 GAK65214.1 - 0.057 14.0 3.6 1.3 9.6 0.0 3.5 2 1 0 2 2 2 0 Ctr copper transporter family IRK PF01007.20 GAK65214.1 - 1 9.2 3.5 17 5.2 0.5 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain ADK PF00406.22 GAK65215.1 - 1.9e-46 157.9 0.0 2.5e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAK65215.1 - 5.4e-24 85.1 0.0 1.5e-23 83.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 GAK65215.1 - 1.5e-14 53.6 0.0 2.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAK65215.1 - 4.4e-05 24.0 0.0 7.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAK65215.1 - 0.00044 20.4 0.2 0.0061 16.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAK65215.1 - 0.047 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase Hydin_ADK PF17213.3 GAK65215.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain adh_short_C2 PF13561.6 GAK65216.1 - 1.1e-52 178.9 0.1 1.9e-52 178.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK65216.1 - 1.7e-48 164.7 0.4 2.7e-48 164.0 0.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK65216.1 - 6.3e-12 45.8 0.3 8.2e-12 45.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAK65216.1 - 0.0011 18.5 0.1 0.0021 17.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAK65216.1 - 0.037 13.1 0.5 0.28 10.2 0.2 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAK65216.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Herpes_ICP4_N PF03584.15 GAK65217.1 - 0.047 13.5 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region DUF3087 PF11286.8 GAK65217.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) SR-25 PF10500.9 GAK65217.1 - 0.67 9.5 16.9 0.78 9.3 16.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 GAK65218.1 - 0.085 13.5 0.9 0.34 11.5 0.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Aldo_ket_red PF00248.21 GAK65219.1 - 2.2e-43 148.5 0.0 8.7e-41 140.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_4 PF12146.8 GAK65220.1 - 0.037 13.3 0.0 0.081 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK65220.1 - 0.058 14.0 0.6 0.09 13.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Fe-ADH PF00465.19 GAK65221.1 - 1.3e-91 307.2 0.0 1.7e-91 306.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAK65221.1 - 1.3e-11 44.7 0.0 7.6e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase RHH_3 PF12651.7 GAK65222.1 - 0.078 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix domain DNA_ligase_A_M PF01068.21 GAK65222.1 - 0.097 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 ATP dependent DNA ligase domain MAPEG PF01124.18 GAK65223.1 - 6.2e-12 45.6 7.0 7.8e-12 45.2 7.0 1.1 1 0 0 1 1 1 1 MAPEG family HupE_UreJ_2 PF13795.6 GAK65223.1 - 0.053 13.2 0.3 0.47 10.1 0.4 1.9 2 0 0 2 2 2 0 HupE / UreJ protein AMP-binding PF00501.28 GAK65224.1 - 2.1e-74 250.6 0.2 2.7e-74 250.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK65224.1 - 1.7e-16 60.9 0.2 5e-16 59.4 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_GDSL_2 PF13472.6 GAK65225.1 - 8.8e-19 68.6 0.4 1.2e-18 68.2 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAK65225.1 - 5e-07 29.9 0.0 6.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SAVED PF18145.1 GAK65225.1 - 0.0032 17.3 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 SMODS-associated and fused to various effectors sensor domain Lipase_GDSL_3 PF14606.6 GAK65225.1 - 0.0093 16.1 0.3 2.4 8.2 0.1 2.5 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family MS_channel PF00924.18 GAK65226.1 - 1.7e-22 80.0 1.4 3.2e-22 79.1 1.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 GAK65226.1 - 0.004 16.6 0.2 0.0072 15.8 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAK65226.1 - 0.0074 16.1 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAK65226.1 - 0.19 11.3 0.2 0.34 10.5 0.2 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 GAK65226.1 - 0.2 12.1 0.1 0.42 11.1 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair IQ PF00612.27 GAK65233.1 - 4.2e-05 23.0 0.3 0.00011 21.7 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Urm1 PF09138.11 GAK65234.1 - 6.1e-35 119.5 0.1 6.9e-35 119.3 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 GAK65234.1 - 2.8e-06 27.9 0.1 3.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 ThiS family Glyco_hydro_47 PF01532.20 GAK65235.1 - 1.3e-155 518.8 0.0 1.5e-155 518.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CX9C PF16860.5 GAK65237.1 - 2.9e-17 62.4 7.0 1.5e-13 50.5 1.2 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UCR_hinge PF02320.16 GAK65237.1 - 0.00058 20.0 8.5 0.0012 19.0 0.7 2.9 1 1 1 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 GAK65237.1 - 0.0084 16.2 3.3 0.21 11.8 1.0 3.1 2 1 1 3 3 3 2 CHCH domain Cmc1 PF08583.10 GAK65237.1 - 0.065 13.3 8.3 0.43 10.6 1.3 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 GAK65237.1 - 0.1 12.8 6.5 1 9.6 0.3 2.4 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 GAK65237.1 - 0.21 12.0 3.9 4.9 7.6 0.7 2.7 1 1 2 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.13 GAK65237.1 - 0.25 11.1 3.3 1 9.1 0.3 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3128 PF11326.8 GAK65237.1 - 0.74 10.2 8.1 2.3 8.6 0.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3128) GCK PF07802.11 GAK65237.1 - 1.1 9.8 4.3 22 5.6 0.2 2.6 1 1 3 4 4 4 0 GCK domain MTCP1 PF08991.10 GAK65237.1 - 5.4 7.3 10.2 6.9 7.0 1.9 3.0 2 1 0 2 2 2 0 Mature-T-Cell Proliferation I type zf-C2HC5 PF06221.13 GAK65238.1 - 6.3e-16 58.1 4.9 1e-15 57.5 4.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PRCC PF10253.9 GAK65238.1 - 0.002 18.9 1.4 0.0087 16.9 0.0 2.4 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DZR PF12773.7 GAK65238.1 - 0.47 10.5 4.7 0.87 9.7 4.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon DHHC PF01529.20 GAK65239.1 - 3e-31 108.3 0.1 3e-31 108.3 0.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase TackOD1 PF18551.1 GAK65239.1 - 0.046 13.4 0.4 0.072 12.8 0.4 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 DUF2613 PF11021.8 GAK65239.1 - 0.062 13.4 1.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) His_Phos_2 PF00328.22 GAK65240.1 - 1.4e-10 41.1 0.0 8.5e-06 25.3 0.1 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Aa_trans PF01490.18 GAK65241.1 - 7.8e-78 262.0 14.7 9.5e-78 261.7 14.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IMS PF00817.20 GAK65242.1 - 1.8e-38 131.9 0.0 5.3e-38 130.4 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 GAK65242.1 - 4.4e-16 59.0 0.4 9.2e-16 58.0 0.4 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 GAK65242.1 - 3.3e-11 43.9 0.0 1.1e-10 42.2 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 GAK65242.1 - 1.1e-06 28.9 0.0 3.7e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAK65242.1 - 0.00026 21.3 0.0 0.00059 20.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain UBM PF14377.6 GAK65242.1 - 0.0014 18.0 9.2 0.15 11.5 0.1 4.1 4 0 0 4 4 4 2 Ubiquitin binding region IMS_HHH PF11798.8 GAK65242.1 - 0.016 15.5 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif DUF1805 PF08827.11 GAK65242.1 - 0.061 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) PALP PF00291.25 GAK65245.1 - 6.9e-54 183.2 0.0 3e-26 92.5 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme LapA_dom PF06305.11 GAK65245.1 - 0.16 11.8 0.9 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TFR_dimer PF04253.15 GAK65246.1 - 9.6e-23 80.6 0.0 2.1e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAK65246.1 - 1.1e-18 67.6 0.1 1.9e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAK65246.1 - 8.4e-15 54.6 1.1 1.9e-14 53.5 1.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAK65246.1 - 0.075 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 GAK65246.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Mito_carr PF00153.27 GAK65247.1 - 5.3e-57 189.7 3.3 6.1e-19 67.7 0.3 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAK65247.1 - 0.13 11.4 2.2 2.4 7.3 0.0 3.2 3 2 0 3 3 3 0 Gammaproteobacterial serine protease Bac_luciferase PF00296.20 GAK65248.1 - 9.7e-63 212.5 3.7 1.3e-62 212.1 3.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TPR_16 PF13432.6 GAK65248.1 - 0.31 11.7 3.3 0.99 10.1 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Trehalase PF01204.18 GAK65251.1 - 3.3e-114 382.5 1.6 3.3e-103 346.2 0.0 2.1 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 GAK65251.1 - 0.00013 21.0 0.3 0.00045 19.3 0.0 1.8 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase DFF-C PF09033.10 GAK65251.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain DUF1635 PF07795.11 GAK65251.1 - 0.62 9.9 4.0 1.1 9.0 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PNK3P PF08645.11 GAK65252.1 - 2.9e-45 153.9 0.0 4.3e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 GAK65252.1 - 6.5e-22 78.2 1.9 1.3e-12 48.1 0.3 2.7 2 1 1 3 3 3 2 AAA domain Zeta_toxin PF06414.12 GAK65252.1 - 0.0011 18.3 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 GAK65252.1 - 0.016 15.6 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 GAK65252.1 - 0.064 12.7 1.6 1.8 8.0 1.6 2.1 1 1 0 1 1 1 0 Chromatin associated protein KTI12 G_glu_transpept PF01019.21 GAK65253.1 - 1e-142 476.6 0.4 1.2e-142 476.4 0.4 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ACOX PF01756.19 GAK65254.1 - 8.2e-44 149.3 0.9 2e-43 148.0 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAK65254.1 - 8.2e-24 84.5 0.1 1.7e-23 83.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAK65254.1 - 6e-13 48.8 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAK65254.1 - 0.00038 20.7 0.4 0.023 14.9 0.4 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 GAK65255.1 - 4.7e-06 26.6 11.0 8.2e-06 25.9 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 GAK65256.1 - 1.4e-16 60.6 1.6 2.3e-16 59.8 1.6 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 AMP-binding PF00501.28 GAK65256.1 - 4.7e-06 25.5 0.0 8.3e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PAN_4 PF14295.6 GAK65257.1 - 0.0012 18.8 0.4 0.0028 17.5 0.4 1.7 1 0 0 1 1 1 1 PAN domain Trp_oprn_chp PF09534.10 GAK65257.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Methyltransf_12 PF08242.12 GAK65258.1 - 1.2e-06 29.1 0.0 2.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK65258.1 - 8.1e-06 26.4 0.1 2.7e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK65258.1 - 3.3e-05 24.5 0.0 0.00036 21.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK65258.1 - 7.3e-05 22.7 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 GAK65258.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 GAK65258.1 - 0.14 13.2 0.0 0.27 12.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain HSP90 PF00183.18 GAK65258.1 - 0.2 10.5 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Hsp90 protein Sugar_tr PF00083.24 GAK65259.1 - 5.2e-109 365.1 15.5 6.4e-109 364.8 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK65259.1 - 2.1e-17 63.1 44.9 2e-14 53.3 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 GAK65259.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Zn_clus PF00172.18 GAK65260.1 - 0.035 14.2 8.3 0.18 12.0 8.4 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Meis_PKNOX_N PF16493.5 GAK65260.1 - 0.084 13.2 0.7 0.29 11.5 0.7 1.9 1 1 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 CDC45 PF02724.14 GAK65260.1 - 1.1 7.4 3.9 1.4 7.1 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Phage_integrase PF00589.22 GAK65262.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family DUF1661 PF07877.11 GAK65264.1 - 0.022 14.5 0.8 0.057 13.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Glyco_hydro_42 PF02449.15 GAK65265.1 - 1.6e-116 389.8 4.8 2.1e-116 389.4 4.8 1.2 1 0 0 1 1 1 1 Beta-galactosidase Na_H_Exchanger PF00999.21 GAK65265.1 - 3.1e-44 151.3 17.0 4.5e-44 150.8 17.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_42M PF08532.10 GAK65265.1 - 9e-27 93.9 0.0 1.5e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42C PF08533.10 GAK65265.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Cellulase PF00150.18 GAK65265.1 - 0.018 14.5 0.2 0.034 13.6 0.2 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 GAK65265.1 - 0.12 11.9 0.6 0.8 9.3 0.6 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 35 Nas2_N PF18265.1 GAK65266.1 - 6.1e-19 67.7 0.2 1e-18 67.0 0.2 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 GAK65266.1 - 1.6e-08 34.7 0.0 3.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 GAK65266.1 - 1.3e-06 28.7 0.0 2.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 GAK65266.1 - 1.7e-06 27.8 0.4 4.9e-06 26.3 0.4 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAK65266.1 - 0.0022 18.3 0.0 0.0056 17.0 0.0 1.8 1 0 0 1 1 1 1 PDZ domain ABATE PF07336.11 GAK65266.1 - 0.015 15.9 6.0 0.017 15.8 5.1 1.5 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Abhydrolase_1 PF00561.20 GAK65267.1 - 2.5e-09 37.2 0.0 6.9e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK65267.1 - 0.1 11.8 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Miga PF10265.9 GAK65269.1 - 2.9 6.8 7.9 4.1 6.3 7.9 1.1 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 GAK65269.1 - 6.9 5.3 8.4 10 4.8 8.4 1.3 1 0 0 1 1 1 0 Presenilin Chromate_transp PF02417.15 GAK65270.1 - 1.1e-58 197.9 32.8 3.1e-33 115.1 10.0 2.8 3 0 0 3 3 3 2 Chromate transporter Acetyltransf_3 PF13302.7 GAK65272.1 - 1.3e-09 38.9 0.0 1.7e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK65272.1 - 5.1e-07 29.9 0.0 7.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAK65272.1 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 GAK65272.1 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK65272.1 - 0.037 14.4 0.0 0.083 13.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAK65272.1 - 0.07 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 GAK65272.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HPP PF04982.13 GAK65273.1 - 2.7e-39 134.1 5.9 4.5e-39 133.4 5.9 1.3 1 0 0 1 1 1 1 HPP family Pectate_lyase PF03211.13 GAK65274.1 - 0.26 10.8 0.0 0.44 10.0 0.0 1.2 1 0 0 1 1 1 0 Pectate lyase p450 PF00067.22 GAK65275.1 - 6.6e-68 229.5 0.0 9.2e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Calc_CGRP_IAPP PF00214.19 GAK65276.1 - 0.053 13.9 0.3 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family bZIP_1 PF00170.21 GAK65277.1 - 3.4e-08 33.5 12.1 1.9e-06 27.8 5.2 2.4 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.9 GAK65277.1 - 7.6e-08 32.2 3.8 2e-07 30.9 3.8 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.15 GAK65277.1 - 9.1 6.5 16.0 0.72 10.0 3.2 2.8 3 0 0 3 3 3 0 Basic region leucine zipper NAD_binding_2 PF03446.15 GAK65279.1 - 4.6e-32 111.4 0.3 6.7e-32 110.8 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAK65279.1 - 1.4e-27 96.3 0.2 3.2e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAK65279.1 - 0.048 14.2 0.4 0.19 12.3 0.4 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribonuclease_3 PF00636.26 GAK65280.1 - 1.7e-10 41.4 0.0 5.1e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAK65280.1 - 0.034 14.3 0.1 0.6 10.3 0.1 2.4 1 1 0 1 1 1 0 Ribonuclease-III-like DUF3891 PF13030.6 GAK65280.1 - 0.079 12.7 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Pro_isomerase PF00160.21 GAK65282.1 - 3.7e-42 144.3 0.0 4.2e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DnaJ_CXXCXGXG PF00684.19 GAK65283.1 - 0.052 13.9 6.6 0.12 12.7 1.3 2.3 2 0 0 2 2 2 0 DnaJ central domain FAM83 PF07894.12 GAK65284.1 - 0.053 13.1 0.3 0.077 12.5 0.3 1.2 1 0 0 1 1 1 0 FAM83 A-H Metallophos PF00149.28 GAK65285.1 - 1.5e-18 68.1 0.2 4.4e-18 66.5 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAK65285.1 - 1.1e-14 55.0 0.1 3.1e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAK65285.1 - 1.3e-13 51.3 5.6 3.5e-13 49.9 5.6 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 GAK65285.1 - 0.0015 19.0 0.7 0.0035 17.8 0.7 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 GAK65285.1 - 0.77 10.1 3.7 5 7.5 1.5 2.6 2 1 0 2 2 2 0 Fibronectin type III domain Atg14 PF10186.9 GAK65286.1 - 2.8 6.9 7.2 9.5 5.2 4.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 GAK65286.1 - 6.3 7.1 8.5 1 9.6 3.8 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 GAK65288.1 - 1.4e-10 41.1 0.2 2.2e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 GAK65288.1 - 0.028 14.5 2.2 0.45 10.6 2.2 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad3 FliT PF05400.13 GAK65288.1 - 0.11 13.3 4.5 1.5 9.7 1.0 2.7 2 1 1 3 3 3 0 Flagellar protein FliT FliD_N PF02465.18 GAK65288.1 - 0.44 11.3 0.2 0.44 11.3 0.2 2.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Utp11 PF03998.13 GAK65288.1 - 2.3 8.1 7.8 13 5.7 0.1 2.0 1 1 1 2 2 2 0 Utp11 protein Complex1_LYR PF05347.15 GAK65289.1 - 7.7e-08 32.3 0.1 7.7e-08 32.3 0.1 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAK65289.1 - 0.00072 20.3 0.8 0.001 19.7 0.8 1.3 1 1 0 1 1 1 1 Complex1_LYR-like adh_short_C2 PF13561.6 GAK65290.1 - 1.3e-42 146.0 0.0 1.8e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK65290.1 - 4.8e-40 137.1 0.1 8.5e-40 136.3 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK65290.1 - 4.7e-05 23.4 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Cofilin_ADF PF00241.20 GAK65291.1 - 4.9e-19 68.3 0.0 2.2e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2985 PF11204.8 GAK65292.1 - 1.1e-22 80.0 0.2 1.1e-22 80.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) NOA36 PF06524.12 GAK65292.1 - 4.2 6.6 8.9 11 5.2 2.6 2.6 2 0 0 2 2 2 0 NOA36 protein Herpes_DNAp_acc PF04929.12 GAK65292.1 - 6.6 5.6 9.4 15 4.4 9.4 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TraY PF05509.11 GAK65293.1 - 7.2 6.7 6.9 1.1 9.4 2.5 1.8 2 0 0 2 2 2 0 TraY domain Asp PF00026.23 GAK65294.1 - 4.7e-55 187.2 10.2 1e-54 186.1 10.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK65294.1 - 9.3e-07 29.3 12.5 0.0036 17.5 0.1 3.8 2 1 2 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAK65294.1 - 0.00049 20.7 0.3 0.02 15.5 0.1 2.9 2 0 0 2 2 2 1 Aspartyl protease PseudoU_synth_2 PF00849.22 GAK65295.1 - 2.4e-25 89.5 0.0 5e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0020 PF01170.18 GAK65295.1 - 6.4e-13 48.8 0.0 1.8e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 GAK65295.1 - 3.7e-08 33.1 0.0 0.0038 16.7 0.0 2.6 1 1 1 2 2 2 2 RRNA methyltransferase AviRa Methyltransf_31 PF13847.6 GAK65295.1 - 0.00046 20.0 0.0 0.00095 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK65295.1 - 0.011 16.4 0.0 0.035 14.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR_2 PF13233.6 GAK65296.1 - 4.4e-21 75.4 0.7 8.1e-21 74.6 0.7 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAK65296.1 - 6e-14 51.8 0.1 1.4e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) His_Phos_2 PF00328.22 GAK65297.1 - 4.7e-21 75.6 0.0 4.5e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Hexokinase_2 PF03727.16 GAK65298.1 - 3.4e-86 288.6 0.1 4.6e-86 288.1 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAK65298.1 - 4.5e-73 245.4 0.0 6.3e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Gly-zipper_Omp PF13488.6 GAK65298.1 - 1.2 9.2 5.9 7.5 6.6 0.9 2.6 2 0 0 2 2 2 0 Glycine zipper Epimerase PF01370.21 GAK65299.1 - 2.3e-21 76.4 0.0 5.4e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK65299.1 - 1.1e-11 44.3 0.0 5e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAK65299.1 - 3.5e-11 42.8 0.1 3.3e-10 39.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAK65299.1 - 1.5e-10 41.3 0.1 7.1e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAK65299.1 - 1.8e-07 30.5 0.0 0.00011 21.5 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAK65299.1 - 8e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 GAK65299.1 - 0.0024 18.2 0.0 0.0052 17.0 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 GAK65299.1 - 0.0065 16.1 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAK65299.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WH2 PF02205.20 GAK65299.1 - 0.097 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 WH2 motif RTA1 PF04479.13 GAK65300.1 - 2.3e-66 223.4 0.6 3.1e-66 222.9 0.6 1.1 1 0 0 1 1 1 1 RTA1 like protein SET PF00856.28 GAK65301.1 - 0.0056 17.1 0.0 0.024 15.0 0.0 2.1 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAK65301.1 - 0.096 13.4 0.9 0.66 10.7 1.7 2.1 2 1 0 2 2 2 0 Rubisco LSMT substrate-binding MIP PF00230.20 GAK65302.1 - 1e-22 81.0 9.5 1.5e-22 80.4 9.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 GAK65304.1 - 1.2e-37 129.7 0.0 5e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK65304.1 - 2.5e-14 53.2 0.0 4.5e-10 39.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK65304.1 - 0.00033 20.1 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAK65304.1 - 0.042 13.8 0.0 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 GAK65305.1 - 6.3e-22 78.5 0.6 6.5e-21 75.2 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK65305.1 - 1.3e-07 32.5 0.3 1.7e-07 32.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAK65305.1 - 1.4e-07 31.2 0.3 0.00011 21.8 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 GAK65305.1 - 0.0017 17.3 0.0 0.0063 15.4 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Esterase_phd PF10503.9 GAK65305.1 - 0.013 15.0 0.0 0.8 9.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 GAK65305.1 - 0.013 15.3 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 GAK65305.1 - 0.017 14.8 0.1 0.049 13.3 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.14 GAK65305.1 - 0.041 13.2 0.0 0.091 12.1 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase DLH PF01738.18 GAK65305.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Patatin PF01734.22 GAK65305.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.5 1 1 0 1 1 1 0 Patatin-like phospholipase DUF202 PF02656.15 GAK65306.1 - 3e-05 24.4 2.8 0.00043 20.7 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF202) RCC1 PF00415.18 GAK65308.1 - 5e-16 59.1 18.5 0.0038 17.8 0.1 7.4 7 3 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAK65308.1 - 2e-05 24.2 33.1 0.27 11.1 4.1 7.9 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Sigma70_r4_2 PF08281.12 GAK65308.1 - 0.034 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Pyr_redox_2 PF07992.14 GAK65309.1 - 1.2e-49 169.2 0.0 1.5e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK65309.1 - 1.5e-11 44.7 0.0 1.7e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK65309.1 - 0.0023 17.2 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAK65309.1 - 0.075 13.5 0.1 3 8.3 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding TPPII_N PF12583.8 GAK65309.1 - 0.11 13.0 1.6 0.19 12.3 0.0 2.2 4 0 0 4 4 4 0 Tripeptidyl peptidase II N terminal DAO PF01266.24 GAK65309.1 - 0.13 11.8 0.2 28 4.1 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Acetyltransf_3 PF13302.7 GAK65311.1 - 2.9e-21 76.6 0.0 3.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK65311.1 - 4e-05 23.8 0.0 5.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AstA PF04958.12 GAK65311.1 - 0.0089 14.6 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit C2 PF00168.30 GAK65312.1 - 5.2e-23 81.3 0.0 4.1e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain MMM1 PF10296.9 GAK65312.1 - 0.0054 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 EndIII_4Fe-2S PF10576.9 GAK65313.1 - 0.2 12.0 1.1 0.66 10.4 1.1 1.9 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III zf-TRAF PF02176.18 GAK65314.1 - 1.6e-08 35.1 16.9 7.8e-07 29.7 1.9 5.3 3 1 3 6 6 6 4 TRAF-type zinc finger zf-RING_UBOX PF13445.6 GAK65314.1 - 1.6e-06 28.0 9.0 7.1e-06 26.0 9.0 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAK65314.1 - 5.8e-06 26.0 8.1 5.8e-06 26.0 8.1 4.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK65314.1 - 1e-05 25.4 9.1 1e-05 25.4 9.1 3.0 3 1 0 3 3 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAK65314.1 - 7.8e-05 22.9 10.1 7.8e-05 22.9 10.1 4.1 3 1 3 6 6 4 1 Ring finger domain zf-Nse PF11789.8 GAK65314.1 - 0.00012 21.8 8.8 0.00018 21.3 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 GAK65314.1 - 0.00056 19.7 8.9 0.00056 19.7 8.9 3.9 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) DUF4672 PF15716.5 GAK65314.1 - 0.019 14.6 0.7 0.046 13.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) zf-C3HC4_4 PF15227.6 GAK65314.1 - 0.022 14.9 9.4 0.022 14.9 9.4 2.8 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING HALZ PF02183.18 GAK65314.1 - 0.068 13.4 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 GAK65314.1 - 0.13 12.3 0.1 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 bZIP transcription factor zf-ANAPC11 PF12861.7 GAK65314.1 - 0.36 10.9 5.7 2.2 8.4 5.7 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TRAF_2 PF15965.5 GAK65314.1 - 2.2 8.8 22.8 7.8 7.0 2.4 3.9 1 1 2 3 3 3 0 TRAF-like zinc-finger zf-RING_6 PF14835.6 GAK65314.1 - 2.8 7.9 8.8 0.17 11.8 2.9 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Aa_trans PF01490.18 GAK65315.1 - 3.2e-61 207.3 11.6 3.9e-61 207.0 11.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAK65315.1 - 0.00017 20.7 9.5 0.00017 20.7 9.5 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Peptidase_M20 PF01546.28 GAK65316.1 - 6.1e-36 124.1 0.0 7.9e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAK65316.1 - 1.1e-10 41.4 0.0 4.8e-10 39.3 0.0 2.1 2 1 0 2 2 2 1 Peptidase dimerisation domain Sedlin_N PF04628.13 GAK65317.1 - 1.3e-18 67.4 0.0 1.7e-17 63.8 0.0 2.0 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region FAD_binding_7 PF03441.14 GAK65318.1 - 1.9e-66 223.4 0.0 2.7e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAK65318.1 - 5e-39 133.9 0.1 8.8e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase MMgT PF10270.9 GAK65319.1 - 1e-17 64.3 0.1 1.2e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter AA_permease_2 PF13520.6 GAK65320.1 - 1.5e-57 195.4 55.3 1.9e-57 195.0 55.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAK65320.1 - 4.6e-33 114.5 49.4 6e-33 114.2 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2905 PF11146.8 GAK65320.1 - 2.1 8.6 8.9 1.3 9.2 3.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2905) DUF2614 PF11023.8 GAK65320.1 - 2.8 8.1 5.9 3.7 7.7 0.4 3.2 2 1 0 2 2 2 0 Zinc-ribbon containing domain 4HBT PF03061.22 GAK65321.1 - 2.3e-18 66.3 4.5 1.2e-09 38.4 0.1 2.7 2 0 0 2 2 2 2 Thioesterase superfamily FAM176 PF14851.6 GAK65321.1 - 0.15 11.7 0.2 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 FAM176 family ABC_tran PF00005.27 GAK65322.1 - 1.9e-43 148.3 0.4 3.4e-22 79.4 0.0 4.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAK65322.1 - 4.6e-12 46.4 5.9 0.0076 16.1 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAK65322.1 - 6.8e-12 45.3 0.0 0.00011 21.8 0.0 3.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK65322.1 - 2.3e-09 36.8 0.3 0.00072 19.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAK65322.1 - 5.6e-07 29.6 1.9 0.0016 18.5 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK65322.1 - 5.9e-06 26.3 0.9 0.016 15.1 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 GAK65322.1 - 2e-05 24.6 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 GAK65322.1 - 2.1e-05 25.0 0.7 0.062 13.7 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 GAK65322.1 - 2.2e-05 24.3 13.3 0.00015 21.6 0.1 4.3 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.6 GAK65322.1 - 3.3e-05 24.5 13.9 0.0019 18.7 0.0 3.6 4 1 0 4 4 2 2 AAA domain AAA_22 PF13401.6 GAK65322.1 - 3.9e-05 23.9 0.3 0.14 12.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAK65322.1 - 7e-05 22.7 1.0 0.7 9.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 GAK65322.1 - 9.2e-05 22.9 0.0 0.63 10.5 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAK65322.1 - 0.00011 22.4 0.1 0.17 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain ABC_tran_Xtn PF12848.7 GAK65322.1 - 0.00037 20.5 6.2 0.00037 20.5 6.2 2.1 2 0 0 2 2 1 1 ABC transporter AAA_27 PF13514.6 GAK65322.1 - 0.00039 20.1 1.4 0.26 10.9 0.0 3.4 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 GAK65322.1 - 0.00044 19.5 0.0 0.58 9.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_19 PF13245.6 GAK65322.1 - 0.00072 19.9 1.0 0.33 11.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 GAK65322.1 - 0.001 18.6 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAK65322.1 - 0.0019 18.0 0.8 1.4 8.6 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein Dynamin_N PF00350.23 GAK65322.1 - 0.0032 17.6 1.0 0.21 11.6 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_14 PF13173.6 GAK65322.1 - 0.0042 17.1 0.0 3.3 7.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 GAK65322.1 - 0.0049 17.2 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 GAK65322.1 - 0.0051 16.8 1.8 7 6.7 0.2 3.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAK65322.1 - 0.0051 16.5 0.4 1.4 8.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 GAK65322.1 - 0.0089 15.9 0.4 0.74 9.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 GAK65322.1 - 0.011 15.7 0.5 1.6 8.6 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GAK65322.1 - 0.02 14.5 1.5 4.9 6.7 0.3 3.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 GAK65322.1 - 0.02 15.1 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-grasp_3 PF02655.14 GAK65322.1 - 0.024 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SRP54 PF00448.22 GAK65322.1 - 0.035 13.7 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 GAK65322.1 - 0.05 13.5 3.4 1.6 8.6 0.1 3.0 3 0 0 3 3 2 0 NTPase SbcCD_C PF13558.6 GAK65322.1 - 0.051 13.8 0.0 0.39 11.0 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 GAK65322.1 - 0.053 12.3 6.8 0.18 10.6 0.0 3.2 4 0 0 4 4 4 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 GAK65322.1 - 0.056 13.6 4.8 1.9 8.6 0.0 3.6 3 1 0 3 3 3 0 AAA domain MukB PF04310.12 GAK65322.1 - 0.057 13.2 0.3 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal Septin PF00735.18 GAK65322.1 - 0.072 12.4 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Septin Mg_chelatase PF01078.21 GAK65322.1 - 0.1 11.9 0.2 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 GAK65322.1 - 0.17 11.4 2.4 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 GAK65322.1 - 0.22 10.5 7.9 2.6 7.0 0.1 3.8 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 GAK65322.1 - 0.38 10.1 3.6 4 6.7 0.1 2.9 3 0 0 3 3 2 0 FtsK/SpoIIIE family FAM25 PF15825.5 GAK65322.1 - 2.5 8.5 7.5 0.3 11.5 1.3 2.6 2 0 0 2 2 2 0 FAM25 family AAA_18 PF13238.6 GAK65322.1 - 7.8 7.1 9.2 8.9 6.9 2.2 3.3 3 1 0 3 3 2 0 AAA domain Presenilin PF01080.17 GAK65322.1 - 7.8 5.1 6.4 0.4 9.4 0.2 1.8 2 0 0 2 2 2 0 Presenilin F-box-like PF12937.7 GAK65323.1 - 4.5e-11 42.5 0.2 1.2e-10 41.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK65323.1 - 9.1e-08 31.8 0.0 2.3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain TPR_9 PF13371.6 GAK65323.1 - 3.2e-05 24.0 3.0 0.00013 22.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAK65323.1 - 0.00014 21.7 2.3 0.016 15.3 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAK65323.1 - 0.0014 19.1 0.2 0.0086 16.6 0.2 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAK65323.1 - 0.0015 18.2 1.2 0.011 15.6 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAK65323.1 - 0.0015 18.6 0.3 0.083 13.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAK65323.1 - 0.0044 16.3 1.5 0.0085 15.3 1.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box_4 PF15966.5 GAK65323.1 - 0.017 15.0 0.1 0.055 13.4 0.1 2.0 1 0 0 1 1 1 0 F-box TPR_14 PF13428.6 GAK65323.1 - 2.2 9.3 6.4 14 6.8 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAK65323.1 - 2.7 8.7 7.7 4.5 8.0 1.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAK65323.1 - 6.9 7.0 8.1 9.4 6.6 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ADH_N PF08240.12 GAK65324.1 - 7.9e-27 93.3 2.3 1.9e-26 92.1 2.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK65324.1 - 8.7e-23 80.7 0.1 1.3e-22 80.2 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAK65324.1 - 2.7e-11 43.4 0.2 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAK65324.1 - 0.00089 20.3 0.0 0.0026 18.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 GAK65324.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1495 PF07381.11 GAK65324.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) FMO-like PF00743.19 GAK65325.1 - 8.5e-19 67.4 0.0 5e-18 64.8 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAK65325.1 - 5.9e-17 61.8 2.0 1e-12 47.9 0.5 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK65325.1 - 2.7e-14 53.2 0.1 2.3e-09 37.0 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK65325.1 - 2.8e-10 40.3 1.9 1.8e-08 34.5 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK65325.1 - 4.4e-08 33.1 4.7 2.3e-07 30.7 1.3 3.0 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAK65325.1 - 6.4e-08 33.1 1.2 0.0028 18.2 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAK65325.1 - 6.8e-07 28.7 0.2 0.00046 19.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 GAK65325.1 - 6.8e-07 28.8 0.9 0.014 14.7 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GAK65325.1 - 4.6e-06 26.2 0.1 0.0011 18.3 0.0 2.9 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 GAK65325.1 - 6.3e-05 23.0 6.2 0.00046 20.2 0.3 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 GAK65325.1 - 0.00023 21.2 0.1 0.52 10.4 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GAK65325.1 - 0.00038 19.8 1.3 0.091 12.0 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 GAK65325.1 - 0.00045 20.6 0.0 0.33 11.4 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 GAK65325.1 - 0.0036 17.2 0.2 0.0036 17.2 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAK65325.1 - 0.0066 15.2 3.6 0.097 11.4 0.8 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAK65325.1 - 0.012 15.0 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK65325.1 - 0.016 14.4 0.4 0.016 14.4 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.21 GAK65325.1 - 0.042 13.2 0.5 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 ThiF family GIDA PF01134.22 GAK65325.1 - 0.054 12.6 4.2 1 8.4 0.2 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 GAK65325.1 - 0.24 10.6 2.7 1 8.6 0.2 2.5 3 0 0 3 3 3 0 Thi4 family AA_permease_2 PF13520.6 GAK65326.1 - 4.7e-72 243.1 53.2 6.1e-72 242.8 53.2 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0020 PF01170.18 GAK65327.1 - 5.8e-07 29.4 0.2 6.3e-06 26.0 0.2 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 GAK65327.1 - 0.15 11.3 0.0 0.94 8.7 0.0 1.9 2 0 0 2 2 2 0 N-6 DNA Methylase Acetyltransf_7 PF13508.7 GAK65328.1 - 2.7e-05 24.5 0.0 4.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAK65328.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAK65328.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 GAK65328.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.23 GAK65329.1 - 8.7e-21 74.1 2.2 1.5e-20 73.4 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAK65329.1 - 0.0039 17.2 0.0 0.0097 16.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like AraC_N PF06719.13 GAK65329.1 - 0.23 11.1 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus Lactonase PF10282.9 GAK65330.1 - 2.9e-19 69.5 0.0 1.1e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 GAK65330.1 - 0.096 12.2 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region His_Phos_1 PF00300.22 GAK65336.1 - 2.2e-36 125.4 0.0 4.1e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M50B PF13398.6 GAK65337.1 - 1.3e-62 211.0 15.7 1.6e-62 210.7 15.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DAGK_prokar PF01219.19 GAK65337.1 - 1.3 8.9 7.1 0.67 9.8 2.3 2.4 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Phage_holin_5_1 PF06946.11 GAK65338.1 - 0.045 14.1 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 UPF0029 PF01205.19 GAK65339.1 - 6.6e-33 113.2 0.0 1.4e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 GAK65339.1 - 1.4e-07 31.8 0.0 4.9e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 RWD domain Inhibitor_I9 PF05922.16 GAK65340.1 - 2e-05 25.1 0.0 4.6e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 bVLRF1 PF18826.1 GAK65340.1 - 0.11 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Thioredoxin PF00085.20 GAK65341.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Cwf_Cwc_15 PF04889.12 GAK65341.1 - 2.5 7.8 11.1 0.42 10.3 7.2 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rhomboid PF01694.22 GAK65342.1 - 5.4e-25 88.1 4.7 5.4e-25 88.1 4.7 1.7 2 0 0 2 2 2 1 Rhomboid family DUF155 PF02582.14 GAK65343.1 - 3.3e-49 167.4 0.0 5e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Pyridoxal_deC PF00282.19 GAK65344.1 - 1.4e-66 224.7 0.0 1.8e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 GAK65344.1 - 8.3e-05 22.0 0.0 0.00032 20.1 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAK65344.1 - 0.00012 21.2 0.0 0.00093 18.3 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Methyltransf_31 PF13847.6 GAK65345.1 - 1.1e-19 70.7 0.0 2.4e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK65345.1 - 1.1e-18 67.7 0.0 5.4e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK65345.1 - 3.9e-17 62.7 0.0 2.5e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK65345.1 - 5.7e-15 55.9 0.0 3e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK65345.1 - 2.5e-11 43.7 0.0 3.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK65345.1 - 3.1e-11 43.1 0.0 1e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAK65345.1 - 2.2e-10 40.4 0.0 3.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAK65345.1 - 8.4e-08 32.2 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAK65345.1 - 3.4e-06 26.6 0.0 4.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 GAK65345.1 - 3.7e-06 27.0 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAK65345.1 - 0.00045 19.7 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GAK65345.1 - 0.00092 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase GCD14 PF08704.10 GAK65345.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 GAK65345.1 - 0.0066 16.0 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 TehB PF03848.14 GAK65345.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 GAK65345.1 - 0.032 14.2 0.0 0.072 13.0 0.0 1.5 2 0 0 2 2 1 0 Methyltransferase domain MetW PF07021.12 GAK65345.1 - 0.044 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 GAK65345.1 - 0.064 12.9 0.2 0.8 9.4 0.2 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.18 GAK65345.1 - 0.1 11.9 0.0 0.51 9.6 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase domain Fibrillarin PF01269.17 GAK65345.1 - 0.11 11.6 0.1 0.44 9.6 0.0 1.9 2 0 0 2 2 2 0 Fibrillarin N6_Mtase PF02384.16 GAK65345.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase RrnaAD PF00398.20 GAK65345.1 - 0.2 10.7 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DEAD PF00270.29 GAK65346.1 - 2.2e-25 89.4 0.0 3.7e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 GAK65346.1 - 1.4e-18 67.4 1.0 4.7e-18 65.7 1.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 GAK65346.1 - 4.4e-14 52.8 0.1 2.2e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK65346.1 - 1.4e-06 28.4 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 GAK65346.1 - 3.9e-06 27.3 0.0 9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like T2SSE PF00437.20 GAK65346.1 - 0.062 12.3 0.0 0.17 11.0 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein G10 PF01125.17 GAK65347.1 - 2.9e-32 111.4 0.7 3.2e-32 111.3 0.7 1.0 1 0 0 1 1 1 1 G10 protein DUF5347 PF17282.2 GAK65347.1 - 0.011 16.1 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5347) Pkinase PF00069.25 GAK65348.1 - 6.9e-70 235.4 0.0 7.7e-61 205.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK65348.1 - 3.8e-32 111.6 0.0 3e-26 92.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK65348.1 - 0.0016 17.9 3.3 3.1 7.0 0.1 3.3 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 GAK65348.1 - 0.052 12.3 0.4 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase zf-RING_11 PF17123.5 GAK65348.1 - 0.057 13.2 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger RIO1 PF01163.22 GAK65348.1 - 0.065 12.8 2.0 0.29 10.7 0.2 2.2 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 GAK65348.1 - 0.17 11.8 5.8 0.55 10.1 0.0 3.1 3 1 1 4 4 4 0 Phosphotransferase enzyme family G_glu_transpept PF01019.21 GAK65349.1 - 2.6e-139 465.3 2.3 9.5e-138 460.1 2.3 2.0 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase GST_N_3 PF13417.6 GAK65351.1 - 0.0025 18.2 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK65351.1 - 0.028 14.7 0.0 0.065 13.5 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAK65351.1 - 0.087 13.0 0.0 0.26 11.5 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Lipase_3 PF01764.25 GAK65353.1 - 4.3e-16 59.0 0.0 8.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) CENP-B_dimeris PF09026.10 GAK65353.1 - 2.5 8.5 6.0 6.4 7.2 6.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MR_MLE_C PF13378.6 GAK65354.1 - 4.4e-47 160.5 0.9 4.2e-46 157.3 0.7 2.3 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAK65354.1 - 0.00034 20.8 0.0 0.00074 19.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 GAK65354.1 - 0.0062 15.7 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Abhydrolase_3 PF07859.13 GAK65355.1 - 3e-10 40.3 0.0 1.6e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK65355.1 - 3.1e-06 28.0 4.9 4.5e-06 27.4 4.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAK65355.1 - 5.5e-05 22.7 0.1 0.00073 19.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAK65355.1 - 0.018 14.7 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 GAK65355.1 - 0.07 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LysM PF01476.20 GAK65356.1 - 1e-12 47.9 0.0 3.3e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain TFIIA PF03153.13 GAK65356.1 - 0.2 11.6 21.7 0.25 11.3 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.15 GAK65356.1 - 0.58 9.6 8.5 0.77 9.2 8.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4778 PF16008.5 GAK65356.1 - 0.68 9.9 12.0 0.97 9.4 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) KOG2701 PF09762.9 GAK65356.1 - 1.8 8.8 9.2 3.2 8.0 9.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) PCRF PF03462.18 GAK65358.1 - 3e-40 138.2 0.7 3e-40 138.2 0.7 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAK65358.1 - 2.6e-36 124.1 2.0 6e-36 122.9 2.0 1.6 1 0 0 1 1 1 1 RF-1 domain DUF3095 PF11294.8 GAK65358.1 - 0.11 11.5 0.6 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3095) HLH PF00010.26 GAK65359.1 - 6.1e-09 35.7 0.0 5.7e-08 32.6 0.0 2.5 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF5094 PF17015.5 GAK65359.1 - 1.6 8.8 4.1 3.1 7.9 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) DUF4097 PF13349.6 GAK65360.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative adhesin CfAFP PF05264.11 GAK65361.1 - 0.099 12.6 0.5 0.23 11.4 0.5 1.5 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) ECH_1 PF00378.20 GAK65363.1 - 1.1e-42 146.1 0.1 8.4e-41 139.9 0.1 2.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK65363.1 - 7.7e-26 91.4 1.4 7.3e-24 84.9 0.3 2.6 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PS_Dcarbxylase PF02666.15 GAK65364.1 - 9.1e-74 247.3 0.0 1.1e-55 188.2 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylserine decarboxylase Pmp3 PF01679.17 GAK65364.1 - 8.5e-24 83.5 11.8 1.4e-23 82.8 11.8 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NADH_oxidored PF08040.11 GAK65364.1 - 0.068 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 MNLL subunit Nnf1 PF03980.14 GAK65365.1 - 8.8e-14 51.8 7.8 8.8e-14 51.8 7.8 2.8 2 2 1 4 4 4 1 Nnf1 TolA_bind_tri PF16331.5 GAK65365.1 - 0.00087 19.3 7.9 0.00087 19.3 7.9 2.8 2 1 1 3 3 3 1 TolA binding protein trimerisation Filament PF00038.21 GAK65365.1 - 0.0012 18.5 10.5 0.0012 18.5 10.5 1.9 2 1 0 2 2 2 1 Intermediate filament protein Dynein_C PF18199.1 GAK65365.1 - 0.0017 17.7 1.6 0.0025 17.1 1.6 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain DUF2968 PF11180.8 GAK65365.1 - 0.0065 16.1 10.7 0.0065 16.1 10.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2968) FapA PF03961.13 GAK65365.1 - 0.03 12.9 1.4 0.043 12.4 1.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 GAK65365.1 - 0.12 12.5 3.8 0.14 12.4 2.2 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 GAK65365.1 - 0.27 11.3 6.4 0.28 11.2 4.5 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 GAK65365.1 - 0.28 11.6 10.3 0.95 9.9 1.3 3.4 3 0 0 3 3 3 0 Snapin/Pallidin DivIVA PF05103.13 GAK65365.1 - 0.32 11.1 13.6 0.05 13.7 3.9 3.0 3 0 0 3 3 3 0 DivIVA protein Laminin_II PF06009.12 GAK65365.1 - 0.38 10.8 8.3 0.097 12.7 4.3 2.1 2 1 0 2 2 2 0 Laminin Domain II MnmE_helical PF12631.7 GAK65365.1 - 0.38 10.9 12.1 0.74 9.9 12.1 1.6 1 1 0 1 1 1 0 MnmE helical domain DUF4164 PF13747.6 GAK65365.1 - 1.2 9.4 18.2 0.13 12.6 7.5 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF948 PF06103.11 GAK65365.1 - 2 8.7 6.8 1.1 9.6 2.4 2.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 GAK65365.1 - 4.8 7.2 14.9 0.31 11.1 8.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ank_5 PF13857.6 GAK65366.1 - 1.7e-27 95.1 2.3 2.2e-10 40.6 0.0 4.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK65366.1 - 2.9e-24 85.4 0.0 2.3e-12 47.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK65366.1 - 5.9e-24 84.1 1.7 2.3e-12 47.2 0.1 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) FYVE PF01363.21 GAK65366.1 - 7.3e-20 70.9 6.3 7.3e-20 70.9 6.3 3.0 3 0 0 3 3 3 1 FYVE zinc finger Ank_3 PF13606.6 GAK65366.1 - 9.6e-19 65.5 0.2 0.00085 19.6 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 GAK65366.1 - 1.3e-18 66.5 0.8 3.5e-05 24.0 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat zf-RING_2 PF13639.6 GAK65366.1 - 4.5e-08 33.3 4.2 4.5e-08 33.3 4.2 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAK65366.1 - 0.00015 21.6 2.8 0.00015 21.6 2.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAK65366.1 - 0.00026 20.6 4.5 0.00026 20.6 4.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAK65366.1 - 0.0023 17.9 4.1 0.0023 17.9 4.1 2.7 3 0 0 3 3 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAK65366.1 - 0.011 16.0 2.5 0.011 16.0 2.5 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain RINGv PF12906.7 GAK65366.1 - 0.17 12.0 3.3 0.62 10.2 3.3 2.0 1 0 0 1 1 1 0 RING-variant domain PAM2 PF07145.15 GAK65366.1 - 0.2 11.4 0.8 0.6 9.9 0.8 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region FANCL_C PF11793.8 GAK65366.1 - 0.52 10.5 5.6 0.27 11.4 2.3 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain Hist_deacetyl PF00850.19 GAK65368.1 - 5.3e-88 295.4 0.0 8e-88 294.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 GAK65368.1 - 1.2e-32 113.1 0.0 1.9e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain UPF0565 PF10561.9 GAK65368.1 - 0.018 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PTPA PF03095.15 GAK65369.1 - 1e-117 392.9 0.0 1.3e-117 392.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FIST PF08495.10 GAK65370.1 - 1.4e-05 25.2 0.0 0.00011 22.3 0.0 2.0 1 1 1 2 2 2 1 FIST N domain DUF1640 PF07798.11 GAK65371.1 - 6.3e-59 198.9 5.4 7.6e-59 198.7 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) T2SSK PF03934.13 GAK65371.1 - 0.0096 15.3 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K SPX PF03105.19 GAK65371.1 - 0.028 14.4 6.8 0.033 14.1 6.8 1.1 1 0 0 1 1 1 0 SPX domain DotU PF09850.9 GAK65371.1 - 0.045 13.5 1.1 0.81 9.4 0.0 2.5 2 1 0 2 2 2 0 Type VI secretion system protein DotU Phage_GP20 PF06810.11 GAK65371.1 - 0.056 13.2 3.5 0.079 12.8 3.5 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 HALZ PF02183.18 GAK65371.1 - 0.38 11.0 5.1 1.6 9.0 5.1 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF5082 PF16888.5 GAK65371.1 - 0.59 10.4 3.5 8.1 6.7 0.1 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) Arf PF00025.21 GAK65372.1 - 7.1e-21 74.4 0.0 9.8e-18 64.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAK65372.1 - 1.1e-08 35.3 0.0 5.3e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAK65372.1 - 1.1e-06 28.0 0.0 8.4e-05 21.9 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Ras PF00071.22 GAK65372.1 - 0.00016 21.3 0.0 0.00084 19.0 0.0 2.0 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 GAK65372.1 - 0.0034 17.4 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Apc13p PF05839.11 GAK65372.1 - 0.0064 16.7 0.0 0.054 13.7 0.0 2.2 2 0 0 2 2 2 1 Apc13p protein RsgA_GTPase PF03193.16 GAK65372.1 - 0.017 15.1 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 GAK65372.1 - 0.033 14.1 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 GAK65372.1 - 0.038 14.4 0.1 0.27 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 GAK65372.1 - 0.053 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 GAK65372.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 GAK65372.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAK65372.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAK65372.1 - 0.22 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) 3HCDH_N PF02737.18 GAK65373.1 - 7.8e-45 153.0 4.1 6.5e-44 150.0 4.1 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAK65373.1 - 2.2e-33 114.8 0.0 4e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.24 GAK65373.1 - 0.15 11.7 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase RGS PF00615.19 GAK65374.1 - 6.4e-38 129.6 0.0 2.3e-37 127.9 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 GAK65374.1 - 8.6e-11 41.7 0.1 0.0068 16.4 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.6 GAK65374.1 - 0.052 13.5 0.1 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix SecE PF00584.20 GAK65375.1 - 0.21 11.5 0.8 0.35 10.8 0.8 1.2 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Lipase_3 PF01764.25 GAK65376.1 - 4.9e-27 94.5 0.0 7.8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 GAK65376.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 GAK65376.1 - 0.016 15.8 2.3 0.016 15.8 2.3 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAK65376.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK65376.1 - 0.095 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RraA-like PF03737.15 GAK65377.1 - 1.5e-34 119.3 0.1 3.7e-34 118.0 0.1 1.7 2 0 0 2 2 2 1 Aldolase/RraA SAP PF02037.27 GAK65377.1 - 4.2e-09 35.9 0.3 7e-09 35.2 0.3 1.4 1 0 0 1 1 1 1 SAP domain DUF1539 PF07560.11 GAK65377.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Macoilin PF09726.9 GAK65377.1 - 2.5 6.6 4.0 4.4 5.8 4.0 1.4 1 0 0 1 1 1 0 Macoilin family UPF0172 PF03665.13 GAK65378.1 - 1.6e-41 142.5 1.2 9.1e-40 136.7 0.1 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0172) JAB PF01398.21 GAK65378.1 - 0.0021 18.0 0.0 0.0048 16.9 0.0 1.6 1 1 1 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_3 PF17176.4 GAK65378.1 - 0.11 12.7 0.3 1 9.7 0.1 2.1 2 0 0 2 2 2 0 tRNA-binding domain TPR_1 PF00515.28 GAK65379.1 - 1.7e-17 62.4 10.4 0.02 14.7 0.0 8.0 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAK65379.1 - 5.4e-17 60.5 23.1 0.067 13.3 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 GAK65379.1 - 1.5e-13 50.2 4.9 0.34 10.6 0.6 6.6 4 2 2 6 6 6 5 TPR repeat TPR_8 PF13181.6 GAK65379.1 - 8.4e-12 44.3 6.5 0.0061 16.7 0.1 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK65379.1 - 8.4e-12 44.9 30.9 0.04 14.7 0.0 9.5 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAK65379.1 - 2.5e-07 30.6 3.0 8.4 7.0 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAK65379.1 - 5.5e-06 26.9 43.3 0.0022 18.6 0.2 8.2 5 2 4 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAK65379.1 - 0.00059 20.3 22.1 0.54 10.8 0.0 7.5 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAK65379.1 - 0.0051 17.1 3.2 0.0051 17.1 3.2 7.0 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAK65379.1 - 0.01 16.0 3.7 0.01 16.0 3.7 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ADK PF00406.22 GAK65380.1 - 3.7e-57 192.7 0.0 4.7e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAK65380.1 - 1.8e-22 80.2 0.2 4.9e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 GAK65380.1 - 9.5e-17 60.7 0.0 2.2e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 GAK65380.1 - 0.00038 20.6 0.0 0.00078 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAK65380.1 - 0.0008 20.0 0.0 0.0028 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAK65380.1 - 0.018 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 GAK65380.1 - 0.034 13.8 0.0 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase AAA_5 PF07728.14 GAK65380.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LPP PF04728.13 GAK65380.1 - 0.071 13.5 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper He_PIG PF05345.12 GAK65381.1 - 0.011 15.9 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 Putative Ig domain Arrestin_C PF02752.22 GAK65383.1 - 2.6e-12 47.4 0.0 6.4e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAK65383.1 - 0.068 13.2 0.1 8.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Galactosyl_T PF01762.21 GAK65384.1 - 5.5e-10 39.4 1.4 0.00016 21.6 0.0 3.7 3 1 1 4 4 4 3 Galactosyltransferase SNF2_N PF00176.23 GAK65385.1 - 4e-56 190.2 0.0 6.3e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 GAK65385.1 - 4.5e-50 170.3 0.6 8.9e-50 169.4 0.1 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 GAK65385.1 - 1.7e-15 57.3 0.0 1.5e-14 54.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK65385.1 - 1e-09 38.6 0.0 2.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAK65385.1 - 5.5e-06 25.8 0.0 3.5e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAK65385.1 - 7.1e-06 25.9 0.0 0.00015 21.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK65385.1 - 0.0047 17.2 0.4 3.1 8.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain L31 PF09784.9 GAK65386.1 - 1e-41 141.4 0.2 1.2e-41 141.3 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 E1-E2_ATPase PF00122.20 GAK65387.1 - 1e-51 175.0 3.0 3e-51 173.5 0.3 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAK65387.1 - 1.1e-44 152.3 4.2 1.7e-44 151.7 2.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAK65387.1 - 9.4e-25 88.1 0.4 5.4e-24 85.7 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK65387.1 - 3.9e-22 77.7 0.0 8.2e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAK65387.1 - 2.1e-18 66.2 0.0 4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAK65387.1 - 1.5e-08 34.7 1.1 7e-06 26.0 0.9 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAK65387.1 - 8.1e-08 32.9 0.0 1.9e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MarR_2 PF12802.7 GAK65387.1 - 0.081 12.8 0.2 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 MarR family S10_plectin PF03501.15 GAK65390.1 - 1.2e-40 137.5 0.1 1.4e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 GAK65390.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) TrmB PF01978.19 GAK65390.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Snf7 PF03357.21 GAK65392.1 - 1e-22 80.6 13.2 1.6e-22 79.9 13.2 1.3 1 0 0 1 1 1 1 Snf7 LPD13 PF18825.1 GAK65392.1 - 0.061 13.1 0.6 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 13 DUF948 PF06103.11 GAK65392.1 - 1.9 8.8 6.4 0.81 10.0 0.3 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PIN_8 PF18476.1 GAK65392.1 - 2.2 8.1 7.3 0.84 9.4 3.4 2.0 1 1 1 2 2 2 0 PIN like domain V_ATPase_I PF01496.19 GAK65392.1 - 3.4 5.5 7.3 2.2 6.1 5.7 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC53 PF10152.9 GAK65392.1 - 3.6 8.0 10.8 1.3 9.4 6.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Fez1 PF06818.15 GAK65392.1 - 7.4 7.0 13.2 10 6.5 12.0 1.7 1 1 1 2 2 2 0 Fez1 HA2 PF04408.23 GAK65393.1 - 8.7e-19 67.8 0.1 2e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAK65393.1 - 3.3e-13 49.9 0.0 2e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAK65393.1 - 1.5e-11 44.5 0.0 4.8e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAK65393.1 - 4.6e-08 33.0 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK65393.1 - 4.3e-05 23.8 0.0 0.0001 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAK65393.1 - 6.9e-05 22.6 0.1 0.00012 21.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAK65393.1 - 0.0069 15.5 0.0 0.019 14.1 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 GAK65393.1 - 0.0089 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAK65393.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 GAK65393.1 - 0.027 13.8 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GAK65393.1 - 0.11 13.0 0.0 0.71 10.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Peptidase_C2 PF00648.21 GAK65394.1 - 4.3e-20 71.9 0.0 9.6e-20 70.8 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 GAK65394.1 - 1.4e-13 51.3 0.0 1.2e-05 25.6 0.0 4.7 3 2 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 GAK65394.1 - 3.2e-10 39.9 0.1 5.2e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 GAK65395.1 - 1.7e-50 171.8 0.0 2.6e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK65395.1 - 7.7e-24 84.4 0.0 2.8e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAK65395.1 - 0.0065 15.5 0.0 0.0097 14.9 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase ubiquitin PF00240.23 GAK65396.1 - 8.3e-137 445.2 18.7 1.5e-33 114.3 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 GAK65396.1 - 5.1e-63 208.8 20.7 3.5e-15 55.6 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAK65396.1 - 5.9e-23 81.1 9.0 0.00052 20.4 0.1 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 GAK65396.1 - 8.7e-16 57.6 3.5 0.036 14.0 0.1 4.3 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAK65396.1 - 2.3e-14 53.4 2.7 0.11 12.7 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAK65396.1 - 3.8e-14 52.8 8.3 0.048 14.0 0.2 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 GAK65396.1 - 8e-13 48.9 1.0 0.37 11.4 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 GAK65396.1 - 9.1e-10 38.6 0.4 1.3 8.8 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 GAK65396.1 - 7.6e-07 28.7 0.6 1.2 8.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase Ubiquitin_4 PF18036.1 GAK65396.1 - 1.1e-06 28.6 24.6 18 5.5 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Big_7 PF17957.1 GAK65396.1 - 7e-06 26.7 0.1 34 5.3 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 GAK65396.1 - 9.4e-06 25.9 0.0 33 4.9 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 GAK65396.1 - 1.1e-05 25.5 3.7 14 5.9 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 GAK65396.1 - 1.3e-05 24.9 4.9 5.9 6.8 0.1 4.3 4 0 0 4 4 4 1 ACT domain TmoB PF06234.12 GAK65396.1 - 1.7e-05 24.8 0.0 32 4.7 0.0 4.7 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 GAK65396.1 - 3.8e-05 23.8 2.7 7.9 6.6 0.0 4.1 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 GAK65396.1 - 0.00054 19.4 0.1 24 4.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 GAK65396.1 - 0.00067 20.2 1.3 74 4.0 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 GAK65396.1 - 0.0045 17.5 0.1 1.6e+02 3.0 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 GAK65396.1 - 0.011 15.9 0.0 1e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 GAK65396.1 - 0.017 15.3 5.2 72 3.6 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 GAK65396.1 - 0.066 13.1 9.2 48 3.9 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 GAK65396.1 - 0.21 11.8 27.2 6.9 7.0 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 GAK65396.1 - 0.59 10.6 9.1 94 3.6 0.1 4.0 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 GAK65396.1 - 1.6 8.9 4.6 2.7e+02 1.8 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 GAK65396.1 - 1.7 8.4 8.5 1.1e+02 2.7 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Ribosomal_S4e PF00900.20 GAK65396.1 - 1.9 8.5 7.5 1.4e+02 2.5 0.1 4.7 4 0 0 4 4 4 0 Ribosomal family S4e Cnl2_NKP2 PF09447.10 GAK65396.1 - 2.2 8.5 10.3 1.1e+02 3.1 0.2 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein AAA_6 PF12774.7 GAK65397.1 - 3.2e-127 424.0 0.0 1.3e-126 422.0 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 GAK65397.1 - 1.2e-118 396.8 2.5 1.2e-118 396.8 2.5 3.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 GAK65397.1 - 4.8e-117 391.9 7.4 4.8e-117 391.9 7.4 3.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 GAK65397.1 - 1.2e-41 142.2 0.0 2.2e-35 121.8 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_8 PF12780.7 GAK65397.1 - 9.2e-37 126.8 0.0 3.2e-36 125.0 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 GAK65397.1 - 3.3e-27 95.2 0.0 2.1e-14 53.7 0.0 5.5 6 0 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 GAK65397.1 - 4.9e-12 46.0 0.0 2.1e-11 44.0 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 GAK65397.1 - 5.9e-12 46.2 0.0 0.0054 17.2 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAK65397.1 - 1.5e-11 44.7 5.8 0.0056 17.0 0.0 6.6 5 1 0 6 6 6 3 AAA domain AAA_33 PF13671.6 GAK65397.1 - 3.3e-08 33.8 1.3 0.2 11.8 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 GAK65397.1 - 1.7e-07 31.8 0.0 1.6 9.2 0.0 5.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 GAK65397.1 - 1.9e-07 31.6 6.9 1.4 9.3 0.0 7.1 6 1 1 7 7 5 2 AAA ATPase domain T2SSE PF00437.20 GAK65397.1 - 7.2e-06 25.3 0.0 0.04 13.0 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_19 PF13245.6 GAK65397.1 - 5.8e-05 23.5 5.0 0.3 11.4 0.0 5.4 5 1 1 6 6 5 1 AAA domain AAA_30 PF13604.6 GAK65397.1 - 0.00012 21.9 3.7 4 7.1 0.0 5.2 4 1 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 GAK65397.1 - 0.0004 19.8 4.5 0.61 9.4 0.0 3.7 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 GAK65397.1 - 0.00061 20.0 0.0 0.0024 18.1 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 GAK65397.1 - 0.00081 18.8 0.2 7.6 5.8 0.0 4.1 4 0 0 4 4 4 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 GAK65397.1 - 0.00099 18.9 0.5 0.76 9.5 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Rad17 PF03215.15 GAK65397.1 - 0.0012 18.8 0.1 20 5.0 0.0 4.4 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_29 PF13555.6 GAK65397.1 - 0.0045 16.7 0.1 7.7 6.4 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAK65397.1 - 0.012 15.2 0.4 0.43 10.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GAK65397.1 - 0.013 15.9 0.0 10 6.6 0.0 4.0 4 0 0 4 4 4 0 RNA helicase AAA_11 PF13086.6 GAK65397.1 - 0.021 14.6 2.9 1.3 8.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 GAK65397.1 - 0.03 14.8 3.0 26 5.3 0.0 4.8 5 0 0 5 5 4 0 ABC transporter AAA_24 PF13479.6 GAK65397.1 - 0.052 13.3 0.6 21 4.8 0.0 4.0 4 0 0 4 4 4 0 AAA domain RuvB_N PF05496.12 GAK65397.1 - 0.16 11.7 0.0 9.3 6.0 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain LOH1CR12 PF10158.9 GAK65397.1 - 1 9.4 9.4 0.9 9.6 0.8 4.0 4 0 0 4 4 3 0 Tumour suppressor protein DUF4720 PF15846.5 GAK65398.1 - 0.13 12.2 0.1 0.64 9.9 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4720) Pet100 PF09803.9 GAK65399.1 - 2.5e-28 98.4 0.2 3.5e-28 97.9 0.2 1.2 1 0 0 1 1 1 1 Pet100 LMWPc PF01451.21 GAK65400.1 - 1.6e-32 112.8 0.0 1.9e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase adh_short PF00106.25 GAK65401.1 - 9.7e-13 48.0 1.2 1.4e-11 44.2 1.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK65401.1 - 1.5e-09 37.7 2.2 1.1e-08 35.0 2.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 GAK65401.1 - 0.00039 20.4 0.6 0.00064 19.7 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 GAK65401.1 - 0.013 15.4 0.2 0.051 13.5 0.3 1.9 2 0 0 2 2 2 0 KR domain ApbA PF02558.16 GAK65401.1 - 0.11 12.2 0.2 0.23 11.1 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA RBR PF17208.3 GAK65402.1 - 0.013 16.2 5.6 0.013 16.2 5.6 5.8 5 1 2 7 7 7 0 RNA binding Region DnaJ_C PF01556.18 GAK65403.1 - 4.1e-33 114.6 0.0 6e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAK65403.1 - 8.7e-23 80.2 3.1 1.4e-22 79.6 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAK65403.1 - 8.6e-10 38.8 18.0 8.6e-10 38.8 18.0 2.2 3 0 0 3 3 3 1 DnaJ central domain zf-RRN7 PF11781.8 GAK65403.1 - 9.4 6.0 8.5 6.5 6.5 0.1 3.1 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GYF PF02213.16 GAK65404.1 - 1.1e-17 63.5 0.5 2.2e-17 62.4 0.5 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 GAK65404.1 - 0.0035 17.1 0.0 0.0095 15.7 0.0 1.8 1 0 0 1 1 1 1 GYF domain 2 Hist_deacetyl PF00850.19 GAK65405.1 - 1.9e-83 280.5 0.0 3e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ATP-synt_F PF01990.17 GAK65406.1 - 1.6e-29 102.0 0.2 1.9e-29 101.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 GAK65406.1 - 0.0092 15.8 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 Abhydrolase_8 PF06259.12 GAK65407.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase MFS_1 PF07690.16 GAK65408.1 - 8.6e-47 159.8 46.8 5.2e-46 157.2 47.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAK65408.1 - 1.8e-16 59.7 18.2 3.2e-16 58.9 18.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3098 PF11297.8 GAK65408.1 - 0.22 11.1 5.1 2.1 8.0 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) Spore_coat_CotO PF14153.6 GAK65408.1 - 1.1 9.1 4.5 1.9 8.4 3.1 1.9 2 0 0 2 2 2 0 Spore coat protein CotO OATP PF03137.20 GAK65408.1 - 2.3 6.4 11.2 0.18 10.1 4.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 GAK65409.1 - 6.6e-66 222.9 0.0 8.1e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 GAK65410.1 - 4.8e-07 29.8 10.0 9e-07 28.9 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALAD PF00490.21 GAK65411.1 - 1.1e-124 415.8 0.0 1.3e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase RNA_pol_3_Rpc31 PF11705.8 GAK65412.1 - 1.8e-22 80.7 8.5 3.1e-22 80.0 8.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Glyco_transf_28 PF03033.20 GAK65413.1 - 4.3e-29 101.3 0.0 1e-28 100.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 GAK65413.1 - 1.1e-16 60.8 0.0 9.6e-08 31.9 0.0 2.7 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 GAK65413.1 - 2.9e-11 43.8 0.1 7e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 GAK65413.1 - 5.4e-07 29.9 0.0 2.4e-06 27.8 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 GAK65413.1 - 0.00022 20.2 0.0 0.00044 19.2 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.6 GAK65413.1 - 0.0052 16.9 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Glyco_tran_28_C PF04101.16 GAK65413.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TPR_1 PF00515.28 GAK65414.1 - 9.4e-48 158.2 31.8 1.8e-08 33.9 0.6 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 GAK65414.1 - 2.5e-36 123.4 14.7 5.8e-20 71.0 2.9 3.1 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 GAK65414.1 - 3e-36 120.6 30.3 4.7e-06 26.3 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAK65414.1 - 2.4e-20 71.0 24.6 0.0012 18.9 0.3 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAK65414.1 - 2.2e-19 68.9 22.1 4.4e-08 32.7 0.0 7.5 6 2 2 8 8 8 6 TPR repeat TPR_16 PF13432.6 GAK65414.1 - 5.1e-17 62.2 26.2 1.1e-06 29.2 0.2 6.9 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAK65414.1 - 1.3e-16 59.8 23.2 0.099 13.5 0.0 10.4 6 3 4 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAK65414.1 - 2.3e-16 60.1 19.8 0.00012 22.5 0.0 7.8 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAK65414.1 - 8.5e-16 58.0 25.0 3.2e-10 40.2 0.3 7.8 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAK65414.1 - 1.5e-10 40.7 1.4 0.32 11.5 0.0 6.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAK65414.1 - 7.8e-10 38.3 18.1 0.0075 16.1 0.0 8.6 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAK65414.1 - 1.4e-07 31.5 7.1 0.037 14.2 0.0 6.3 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAK65414.1 - 5.6e-06 26.0 24.2 0.016 15.2 0.1 8.6 10 1 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAK65414.1 - 6e-06 26.6 16.7 1.4 9.7 0.0 8.2 9 0 0 9 9 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK65414.1 - 8.7e-05 22.7 14.5 0.0048 17.1 1.6 4.0 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2H2_jaz PF12171.8 GAK65414.1 - 0.0033 17.7 0.4 0.057 13.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PAS_4 PF08448.10 GAK65414.1 - 0.088 13.1 2.3 2.7 8.3 0.1 3.5 3 0 0 3 3 3 0 PAS fold XPC-binding PF09280.11 GAK65414.1 - 0.63 9.8 4.5 1.2 8.9 2.1 2.7 3 0 0 3 3 2 0 XPC-binding domain Tho2 PF11262.8 GAK65414.1 - 4.9 6.3 10.2 0.27 10.4 3.4 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Suf PF05843.14 GAK65415.1 - 1.3e-88 297.8 1.2 2.8e-82 277.0 0.0 4.5 4 0 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 GAK65415.1 - 2.2e-06 28.0 20.6 0.056 14.3 0.0 8.4 8 1 1 9 9 9 3 Tetratricopeptide repeat DHHC PF01529.20 GAK65416.1 - 2.1e-09 37.6 2.2 7.3e-09 35.8 2.2 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase TEX13 PF15186.6 GAK65416.1 - 0.23 11.2 0.5 0.6 9.8 0.2 1.8 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family STAG PF08514.11 GAK65417.1 - 6.1e-34 116.3 2.4 1.1e-33 115.5 0.8 2.4 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 GAK65417.1 - 0.0071 16.5 0.1 2 8.9 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat PAS PF00989.25 GAK65418.1 - 4.7e-11 42.7 0.0 3.9e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 GAK65418.1 - 4.4e-10 39.8 0.0 1.3e-06 28.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 GAK65418.1 - 3e-08 33.8 0.0 2.4e-07 30.9 0.0 2.4 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAK65418.1 - 7.8e-07 29.3 0.0 5.2e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 GAK65418.1 - 0.083 12.9 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_11 PF14598.6 GAK65418.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain TauD PF02668.16 GAK65419.1 - 3e-39 135.4 0.0 4.9e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 GAK65419.1 - 1.4e-12 48.1 0.2 1.1e-11 45.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 GAK65419.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 CsiD Apt1 PF10351.9 GAK65420.1 - 9e-136 453.5 0.1 9e-136 453.5 0.1 3.5 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 GAK65420.1 - 6.9e-70 236.3 0.6 6.9e-70 236.3 0.6 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 GAK65420.1 - 5.6e-48 163.0 0.0 1.1e-47 162.0 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 GAK65420.1 - 1.9e-41 141.5 0.0 3.7e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 GAK65420.1 - 4.3e-25 88.4 0.0 1.8e-24 86.4 0.0 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CCDC53 PF10152.9 GAK65422.1 - 9.3 6.7 6.5 5.2 7.5 2.3 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Proteasome PF00227.26 GAK65423.1 - 2.4e-57 193.5 0.3 3.9e-57 192.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit Ras PF00071.22 GAK65423.1 - 6.3e-45 152.7 0.0 1e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK65423.1 - 2.5e-15 56.7 0.1 2.1e-14 53.8 0.0 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Proteasome_A_N PF10584.9 GAK65423.1 - 9.3e-14 50.8 0.2 2.1e-13 49.7 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Arf PF00025.21 GAK65423.1 - 5.7e-06 25.9 0.0 9.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAK65423.1 - 0.0037 17.2 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAK65423.1 - 0.0068 16.5 0.2 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK65423.1 - 0.0085 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribonuc_L-PSP PF01042.21 GAK65424.1 - 0.086 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease L-PSP tRNA-synt_1g PF09334.11 GAK65425.1 - 1.1e-91 307.5 1.1 4.9e-80 269.2 0.0 3.0 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAK65425.1 - 1.6e-15 56.4 0.0 1.6e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GAK65425.1 - 2e-07 30.7 0.3 0.013 14.9 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 GAK65425.1 - 0.00048 20.1 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Asp PF00026.23 GAK65426.1 - 2.5e-71 240.7 6.4 4e-71 240.0 6.4 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK65426.1 - 2.8e-11 44.0 2.8 2.8e-11 44.0 2.8 3.2 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal PPR_2 PF13041.6 GAK65427.1 - 6e-06 26.4 0.0 2.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 GAK65427.1 - 0.01 16.0 0.0 0.069 13.4 0.0 2.6 1 0 0 1 1 1 0 PPR repeat UPF0261 PF06792.11 GAK65428.1 - 6.2e-145 483.2 0.0 7e-145 483.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 GAK65429.1 - 2.6e-127 423.6 0.3 2.9e-127 423.4 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like SPOR PF05036.13 GAK65429.1 - 0.074 13.5 0.0 6.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain zf-C2H2 PF00096.26 GAK65430.1 - 1.5e-07 31.5 10.3 0.00064 20.0 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK65430.1 - 0.0013 19.1 4.0 0.0013 19.1 4.0 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAK65430.1 - 0.0013 19.4 9.7 0.096 13.6 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger CCDC24 PF15669.5 GAK65430.1 - 2.1 8.2 4.9 1.5 8.7 0.1 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-H2C2_5 PF13909.6 GAK65430.1 - 5.3 6.9 6.0 7.5 6.4 1.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Sugar_tr PF00083.24 GAK65433.1 - 5.3e-118 394.7 20.2 6.1e-118 394.5 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK65433.1 - 4e-16 58.9 40.5 3.8e-13 49.1 18.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 GAK65433.1 - 1 9.6 10.6 0.086 13.1 4.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) zf-Tim10_DDP PF02953.15 GAK65434.1 - 1.2e-17 63.3 0.5 1.7e-17 62.8 0.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1100 PF06500.11 GAK65435.1 - 4.2e-10 39.0 0.0 7.9e-10 38.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 GAK65435.1 - 3.3e-05 23.7 0.4 0.037 13.7 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK65435.1 - 3.9e-05 23.0 0.1 0.044 13.0 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 TPR_12 PF13424.6 GAK65435.1 - 0.081 13.2 1.6 0.19 12.0 1.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat MA3 PF02847.17 GAK65436.1 - 5.1e-29 100.5 0.1 9.8e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 MA3 domain COX6B PF02297.17 GAK65436.1 - 1.5e-23 82.8 0.5 3.8e-23 81.5 0.5 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb MIF4G PF02854.19 GAK65436.1 - 2.8e-13 50.0 0.7 2.3e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain Cnd1 PF12717.7 GAK65436.1 - 0.068 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Sigma70_ner PF04546.13 GAK65436.1 - 1.1 9.2 7.6 7.3 6.4 1.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CTP_transf_like PF01467.26 GAK65437.1 - 9.3e-27 94.0 0.0 1.5e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Pox_MCEL PF03291.16 GAK65438.1 - 1.1e-76 258.1 0.0 1.8e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 GAK65438.1 - 1.1e-09 38.9 0.0 2.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK65438.1 - 2e-07 30.9 0.0 3.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK65438.1 - 6.3e-07 30.0 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK65438.1 - 4.3e-06 27.4 0.0 9.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK65438.1 - 2e-05 24.5 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAK65438.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family tRNA-synt_1 PF00133.22 GAK65439.1 - 6.8e-149 496.9 0.0 9.7e-149 496.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAK65439.1 - 1.4e-20 73.8 0.0 2.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAK65439.1 - 2.1e-20 72.8 0.0 2.6e-12 46.2 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAK65439.1 - 0.0019 17.8 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Zn_clus PF00172.18 GAK65442.1 - 6.1e-06 26.2 7.5 1.2e-05 25.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CNDH2_M PF16869.5 GAK65442.1 - 1.8 9.2 7.1 5.9 7.6 0.9 2.6 2 0 0 2 2 2 0 PF16858 Glyco_trans_2_3 PF13632.6 GAK65444.1 - 1.4e-45 155.6 2.4 1.4e-45 155.6 2.4 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAK65444.1 - 4.1e-06 26.7 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAK65444.1 - 0.00053 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_16 PF00722.21 GAK65446.1 - 7.6e-18 64.6 0.9 1.4e-17 63.8 0.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 GAK65447.1 - 3.3e-19 69.0 0.7 5.6e-19 68.3 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 GAK65448.1 - 8e-44 149.9 10.4 8e-44 149.9 10.4 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAK65448.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAK65448.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Cutinase PF01083.22 GAK65450.1 - 1.3e-15 57.8 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Cutinase PAP2 PF01569.21 GAK65453.1 - 1.5e-18 66.8 3.6 1.5e-18 66.8 3.6 3.2 3 1 1 4 4 4 1 PAP2 superfamily Carm_PH PF17888.1 GAK65453.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Carmil pleckstrin homology domain AAA PF00004.29 GAK65454.1 - 3.1e-85 283.2 0.0 6.2e-42 143.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK65454.1 - 2.5e-29 100.8 1.1 2.6e-14 52.7 0.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 GAK65454.1 - 1.3e-13 51.1 0.0 4e-07 30.1 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAK65454.1 - 1.9e-12 47.9 1.2 7.2e-06 26.5 0.2 3.8 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 GAK65454.1 - 1e-11 44.8 0.0 5.6e-05 22.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAK65454.1 - 8.4e-09 35.1 0.0 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 GAK65454.1 - 3.9e-08 33.6 0.0 0.00052 20.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAK65454.1 - 3.4e-07 30.6 1.0 0.015 15.6 0.2 4.3 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAK65454.1 - 4.9e-06 26.8 0.0 0.21 11.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAK65454.1 - 1.3e-05 25.7 0.0 0.011 16.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GAK65454.1 - 1.5e-05 25.3 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 GAK65454.1 - 1.5e-05 25.0 0.0 0.032 14.2 0.0 3.3 3 1 1 4 4 3 1 Rad17 P-loop domain AAA_14 PF13173.6 GAK65454.1 - 1.8e-05 24.8 0.0 0.027 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GAK65454.1 - 1.9e-05 24.5 0.0 0.036 13.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 GAK65454.1 - 2.4e-05 24.7 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 GAK65454.1 - 4.7e-05 22.9 0.5 0.27 10.6 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 GAK65454.1 - 0.00019 21.4 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAK65454.1 - 0.00023 20.7 0.0 0.087 12.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 GAK65454.1 - 0.00053 20.1 0.0 0.49 10.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 GAK65454.1 - 0.00065 19.3 2.8 0.28 10.7 0.3 3.5 2 2 1 3 3 3 1 AAA domain AAA_3 PF07726.11 GAK65454.1 - 0.0015 18.4 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAK65454.1 - 0.0015 17.8 0.0 0.059 12.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 GAK65454.1 - 0.002 17.9 0.0 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAK65454.1 - 0.003 16.7 0.0 0.047 12.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 GAK65454.1 - 0.0033 16.6 0.0 0.29 10.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 GAK65454.1 - 0.0048 16.6 0.0 1.9 8.1 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 GAK65454.1 - 0.0074 16.1 0.0 0.69 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAK65454.1 - 0.0085 16.0 0.1 0.35 10.8 0.0 3.0 2 1 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 GAK65454.1 - 0.018 14.9 0.3 2.9 7.7 0.0 3.1 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GAK65454.1 - 0.021 15.3 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 GAK65454.1 - 0.03 13.6 0.0 3.6 6.9 0.0 2.6 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 GAK65454.1 - 0.039 13.4 0.4 1.2 8.6 0.2 2.5 2 0 0 2 2 2 0 PhoH-like protein Adeno_IVa2 PF02456.15 GAK65454.1 - 0.051 12.4 0.0 0.71 8.6 0.0 2.5 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_23 PF13476.6 GAK65454.1 - 0.052 14.0 0.0 0.14 12.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 GAK65454.1 - 0.063 13.0 1.1 0.5 10.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain IPT PF01745.16 GAK65454.1 - 0.065 12.6 0.2 1.9 7.8 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 GAK65454.1 - 0.14 11.9 2.1 1.2 8.8 0.1 2.9 3 0 0 3 3 3 0 Cytidylate kinase DAP3 PF10236.9 GAK65454.1 - 0.21 10.7 0.0 0.57 9.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 GDI PF00996.18 GAK65455.1 - 8.5e-34 116.8 0.0 2e-20 72.8 0.0 2.8 3 0 0 3 3 3 2 GDP dissociation inhibitor Sas10_Utp3 PF04000.15 GAK65456.1 - 5.8e-13 49.3 1.3 9.7e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family AKNA PF12443.8 GAK65456.1 - 0.4 11.4 0.0 0.4 11.4 0.0 2.5 3 0 0 3 3 3 0 AT-hook-containing transcription factor Macoilin PF09726.9 GAK65456.1 - 1.1 7.7 6.3 1.4 7.4 0.8 2.4 1 1 2 3 3 3 0 Macoilin family Zn_clus PF00172.18 GAK65457.1 - 2.9e-05 24.1 9.2 7.2e-05 22.8 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKN1 PF03935.15 GAK65458.1 - 3.2e-203 675.7 0.0 3.9e-203 675.4 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAK65458.1 - 0.01 15.3 0.1 0.12 11.9 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolases family 16 zf-C2H2 PF00096.26 GAK65459.1 - 1.7e-12 47.0 14.0 6.4e-06 26.3 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK65459.1 - 1.4e-07 31.7 10.2 0.0066 17.2 0.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAK65459.1 - 1.3e-06 28.2 0.5 0.00025 21.0 0.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK65459.1 - 7.6e-05 23.0 11.8 0.066 13.7 0.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAK65459.1 - 0.11 12.8 3.0 0.51 10.7 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-ribbon_3 PF13248.6 GAK65459.1 - 0.13 11.7 1.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_ZIC PF18366.1 GAK65459.1 - 0.13 12.3 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Zic proteins zinc finger domain Zn-ribbon_8 PF09723.10 GAK65459.1 - 0.29 11.3 3.6 1.5 9.0 0.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 GAK65459.1 - 0.29 11.4 4.1 5.9 7.3 4.7 2.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.6 GAK65459.1 - 0.82 9.6 4.0 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Thiolase_N PF00108.23 GAK65460.1 - 1e-91 306.9 3.9 4.3e-91 304.9 3.9 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAK65460.1 - 2.7e-45 153.0 3.5 1.4e-44 150.6 1.0 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAK65460.1 - 1e-06 28.5 4.1 7.8e-05 22.4 1.2 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain BcrAD_BadFG PF01869.20 GAK65460.1 - 0.0077 15.8 1.3 0.017 14.6 0.1 2.1 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family Dodecin PF07311.12 GAK65460.1 - 0.17 12.1 0.8 6.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Dodecin LMP PF04778.12 GAK65461.1 - 0.11 12.4 0.7 0.22 11.4 0.7 1.4 1 0 0 1 1 1 0 LMP repeated region APG6_N PF17675.1 GAK65461.1 - 0.12 12.9 1.7 0.27 11.7 1.7 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 GAK65461.1 - 0.15 12.3 3.0 0.34 11.1 3.0 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AT_hook PF02178.19 GAK65462.1 - 1.6e-07 30.4 86.4 0.058 13.3 3.5 8.7 8 0 0 8 8 8 7 AT hook motif SlyX PF04102.12 GAK65462.1 - 0.041 14.5 2.8 0.12 13.0 2.8 1.8 1 0 0 1 1 1 0 SlyX PPV_E1_N PF00524.18 GAK65462.1 - 0.056 13.9 0.3 0.056 13.9 0.3 1.8 2 0 0 2 2 2 0 E1 Protein, N terminal domain SKG6 PF08693.10 GAK65463.1 - 0.0039 16.6 0.2 0.013 14.8 0.2 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 GAK65463.1 - 0.025 15.4 0.0 0.077 13.9 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 GAK65463.1 - 0.036 12.8 0.4 0.38 9.4 0.0 2.3 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E SARAF PF06682.12 GAK65463.1 - 0.13 11.9 19.8 0.015 15.0 5.7 2.4 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3318 PF11780.8 GAK65463.1 - 0.7 9.8 3.4 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) Glycoamylase PF10091.9 GAK65463.1 - 1.3 8.5 4.0 2.2 7.8 1.6 2.1 2 0 0 2 2 2 0 Putative glucoamylase ATP19 PF11022.8 GAK65463.1 - 2.3 8.7 0.0 2.3 8.7 0.0 3.9 4 0 0 4 4 4 0 ATP synthase subunit K DAP10 PF07213.11 GAK65463.1 - 4.9 7.2 7.3 0.62 10.1 0.2 2.7 2 0 0 2 2 2 0 DAP10 membrane protein SKG6 PF08693.10 GAK65464.1 - 0.025 14.0 0.7 0.062 12.7 0.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 GAK65464.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAD_binding_1 PF00667.20 GAK65465.1 - 2.6e-54 184.1 0.0 4.3e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAK65465.1 - 6.6e-07 29.9 0.0 2.9e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain POR_N PF01855.19 GAK65465.1 - 0.002 17.9 0.5 0.004 16.9 0.5 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_6 PF00970.24 GAK65465.1 - 0.077 13.4 0.0 0.91 9.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain APG12 PF04110.13 GAK65466.1 - 1.6e-32 111.7 0.0 2.4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 GAK65466.1 - 0.0032 17.7 0.0 0.0048 17.1 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ufm1 PF03671.14 GAK65466.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin fold modifier 1 protein Ribosomal_L30_N PF08079.12 GAK65467.1 - 7.2e-28 96.6 18.3 1.1e-27 96.0 18.3 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GAK65467.1 - 5.6e-17 61.4 2.1 1.2e-16 60.4 2.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Alk_phosphatase PF00245.20 GAK65468.1 - 5.5e-74 249.6 0.0 9.4e-65 219.2 0.0 2.1 2 0 0 2 2 2 2 Alkaline phosphatase Annexin PF00191.20 GAK65469.1 - 6.7e-58 192.7 1.5 1.3e-18 66.8 0.0 4.3 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 GAK65469.1 - 0.0039 17.6 0.1 2.3 8.7 0.0 3.3 4 0 0 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 LRR_4 PF12799.7 GAK65470.1 - 0.017 15.5 0.1 14 6.3 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF3140 PF11338.8 GAK65470.1 - 0.1 13.1 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Y_phosphatase2 PF03162.13 GAK65471.1 - 6.3e-49 165.7 0.0 1.1e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Prefoldin PF02996.17 GAK65471.1 - 1.2e-28 99.4 0.2 1.8e-28 98.9 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Y_phosphatase3 PF13350.6 GAK65471.1 - 2.3e-07 31.0 0.0 8.5e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family BCAS3 PF12490.8 GAK65471.1 - 0.023 14.2 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Syntaxin-6_N PF09177.11 GAK65471.1 - 0.15 12.6 1.7 6 7.5 0.3 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal OHCU_decarbox PF09349.10 GAK65472.1 - 2.5e-25 89.8 0.0 2.5e-25 89.8 0.0 1.9 2 1 1 3 3 3 1 OHCU decarboxylase adh_short PF00106.25 GAK65473.1 - 8.5e-52 175.4 0.1 1.1e-51 175.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK65473.1 - 3.3e-34 118.5 0.1 4.4e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK65473.1 - 2.6e-13 50.3 0.1 3.3e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAK65473.1 - 0.00017 21.2 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAK65473.1 - 0.00083 18.9 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAK65473.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAK65473.1 - 0.0018 18.2 0.5 0.0031 17.4 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 GAK65473.1 - 0.0029 17.0 0.0 0.0069 15.7 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ThiF PF00899.21 GAK65473.1 - 0.016 14.5 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 GAK65473.1 - 0.041 13.5 0.6 0.079 12.6 0.6 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.8 GAK65473.1 - 0.041 13.6 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 GAK65473.1 - 0.054 12.6 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DASH_Dad3 PF08656.10 GAK65475.1 - 3.8e-19 68.5 0.9 6.5e-19 67.8 0.9 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad3 Mce4_CUP1 PF11887.8 GAK65475.1 - 0.013 15.0 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative MetOD2 PF18548.1 GAK65475.1 - 0.017 15.2 0.8 6.5 6.9 0.0 2.5 1 1 2 3 3 3 0 Metanogen output domain 2 Abhydrolase_1 PF00561.20 GAK65476.1 - 5.7e-24 85.2 0.0 6.1e-23 81.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK65476.1 - 1.6e-13 51.8 4.7 2e-13 51.4 4.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK65476.1 - 3.2e-09 36.4 0.0 4.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAK65476.1 - 0.014 14.1 0.0 0.032 12.9 0.0 1.5 2 0 0 2 2 2 0 Ndr family DUF3530 PF12048.8 GAK65476.1 - 0.034 13.6 0.0 0.061 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) PAE PF03283.13 GAK65478.1 - 4.2e-16 59.0 0.9 5.9e-16 58.5 0.9 1.1 1 0 0 1 1 1 1 Pectinacetylesterase RNA_pol_I_A49 PF06870.12 GAK65480.1 - 8.6e-112 373.8 0.0 1.5e-111 373.0 0.0 1.4 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor TMEM247 PF15444.6 GAK65480.1 - 1.7 8.7 0.0 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 247 TFIIE-A_C PF11521.8 GAK65480.1 - 8 6.8 7.0 6.8 7.1 1.8 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF2201_N PF13203.6 GAK65480.1 - 9.4 5.7 8.3 54 3.2 0.0 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain PHP PF02811.19 GAK65481.1 - 1.2e-07 32.2 0.1 4.4e-07 30.4 0.1 1.8 1 1 0 1 1 1 1 PHP domain FA_hydroxylase PF04116.13 GAK65482.1 - 1e-23 84.1 17.6 1e-23 84.1 17.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mtc PF03820.17 GAK65483.1 - 6.3e-115 383.5 0.3 8.5e-115 383.1 0.3 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.32 GAK65484.1 - 2.2e-22 78.9 12.7 0.0029 18.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK65484.1 - 2.4e-05 24.6 0.0 0.36 11.1 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 GAK65484.1 - 0.0014 18.5 0.0 0.012 15.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Ge1_WD40 PF16529.5 GAK65484.1 - 0.0029 16.6 0.0 0.27 10.2 0.0 2.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein gag_pre-integrs PF13976.6 GAK65484.1 - 0.14 12.0 1.1 7.3 6.5 0.5 2.9 3 0 0 3 3 3 0 GAG-pre-integrase domain DAZAP2 PF11029.8 GAK65484.1 - 0.26 12.2 8.5 0.86 10.5 8.5 1.9 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) p450 PF00067.22 GAK65486.1 - 1.8e-26 93.0 0.0 5.3e-26 91.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Septin PF00735.18 GAK65487.1 - 9.6e-112 372.8 0.2 9.6e-112 372.8 0.2 1.9 2 0 0 2 2 2 1 Septin ENTH PF01417.20 GAK65487.1 - 7.2e-50 168.2 0.2 1.6e-49 167.1 0.2 1.6 1 0 0 1 1 1 1 ENTH domain MMR_HSR1 PF01926.23 GAK65487.1 - 1.6e-08 34.7 0.0 4.7e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK65487.1 - 3.3e-07 30.4 0.5 2.7e-06 27.4 0.2 2.6 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 GAK65487.1 - 0.00012 22.3 0.2 0.00044 20.5 0.2 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAK65487.1 - 0.00014 21.5 0.3 0.00014 21.5 0.3 3.8 4 1 0 4 4 4 1 Elongation factor Tu GTP binding domain Ras PF00071.22 GAK65487.1 - 0.00016 21.3 0.1 0.0005 19.7 0.1 1.9 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 GAK65487.1 - 0.00071 19.9 0.1 0.0065 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 GAK65487.1 - 0.0013 18.1 0.1 0.0039 16.6 0.1 1.8 1 0 0 1 1 1 1 AIG1 family ANTH PF07651.16 GAK65487.1 - 0.0014 17.7 1.1 0.0014 17.7 1.1 1.7 2 0 0 2 2 2 1 ANTH domain UIM PF02809.20 GAK65487.1 - 0.003 17.4 14.2 0.0093 15.8 1.2 3.7 3 0 0 3 3 3 2 Ubiquitin interaction motif AAA_16 PF13191.6 GAK65487.1 - 0.0035 17.7 0.0 0.0035 17.7 0.0 3.3 3 1 0 3 3 2 1 AAA ATPase domain AAA_24 PF13479.6 GAK65487.1 - 0.013 15.2 0.1 0.091 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAK65487.1 - 0.027 15.0 0.0 0.027 15.0 0.0 3.3 2 1 0 2 2 1 0 ABC transporter PduV-EutP PF10662.9 GAK65487.1 - 0.027 14.2 0.3 0.57 9.9 0.3 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 GAK65487.1 - 0.034 13.5 0.0 0.12 11.8 0.0 1.9 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 GAK65487.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 GAK65487.1 - 0.071 12.3 0.0 0.18 10.9 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 GAK65487.1 - 0.073 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 GAK65487.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.18 GAK65487.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 GAK65487.1 - 0.14 12.6 1.3 2.2 8.7 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAK65487.1 - 0.76 10.2 0.0 0.76 10.2 0.0 3.1 3 0 0 3 3 3 0 RNA helicase zf-CSL PF05207.13 GAK65488.1 - 4.4e-23 80.8 1.1 7e-23 80.1 1.1 1.3 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 GAK65488.1 - 0.0013 18.8 2.3 0.0019 18.3 2.0 1.5 1 1 0 1 1 1 1 Zinc ribbon domain zf-RING_4 PF14570.6 GAK65488.1 - 0.0027 17.5 0.8 0.0045 16.7 0.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 GAK65488.1 - 0.016 15.1 1.1 0.025 14.5 1.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_7 PF02591.15 GAK65488.1 - 0.038 14.2 0.2 0.09 13.0 0.1 1.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain Lar_restr_allev PF14354.6 GAK65488.1 - 0.043 14.2 0.1 0.068 13.6 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ras PF00071.22 GAK65489.1 - 3.7e-55 186.0 0.1 4.3e-55 185.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK65489.1 - 6.9e-31 107.0 0.0 9e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK65489.1 - 1.6e-16 60.2 0.0 2.3e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK65489.1 - 2e-05 24.6 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAK65489.1 - 0.0027 17.1 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAK65489.1 - 0.004 16.7 0.1 0.0092 15.5 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAK65489.1 - 0.0082 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAK65489.1 - 0.022 14.7 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 GAK65489.1 - 0.04 13.6 0.2 0.095 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GAK65489.1 - 0.25 10.7 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Pil1 PF13805.6 GAK65490.1 - 2.3e-18 66.7 1.3 4.6e-18 65.6 1.3 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 Glyco_hydro_32N PF00251.20 GAK65492.1 - 4e-47 161.3 0.0 5.9e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAK65492.1 - 2.3e-20 73.2 0.0 3.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 GAK65492.1 - 0.0047 17.0 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 GAK65492.1 - 0.041 13.9 0.3 1.7 9.0 0.1 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat TMEM119 PF15724.5 GAK65492.1 - 0.098 12.7 3.3 0.19 11.7 3.3 1.4 1 0 0 1 1 1 0 TMEM119 family MycE_N PF17843.1 GAK65492.1 - 0.15 12.5 1.0 0.31 11.6 1.0 1.4 1 0 0 1 1 1 0 MycE methyltransferase N-terminal Dicty_CAD PF05720.12 GAK65493.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cell-cell adhesion domain MBG_2 PF18676.1 GAK65494.1 - 0.0024 18.5 1.7 0.0045 17.6 0.4 2.1 1 1 1 2 2 2 1 MBG domain (YGX type) EPSP_synthase PF00275.20 GAK65497.1 - 1.1e-116 390.0 0.1 1.6e-116 389.5 0.1 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 GAK65497.1 - 6e-98 327.2 0.0 2.2e-97 325.3 0.0 2.0 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 GAK65497.1 - 7.1e-52 176.9 0.0 1.4e-51 176.0 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 GAK65497.1 - 4.1e-26 91.1 0.0 1.5e-25 89.2 0.0 2.1 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 GAK65497.1 - 5.1e-25 88.4 0.0 9.7e-24 84.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 GAK65497.1 - 3.4e-08 33.1 0.0 7.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 GAK65497.1 - 2e-05 24.6 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 GAK65497.1 - 0.00014 21.7 0.3 0.00056 19.7 0.1 2.1 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase OCD_Mu_crystall PF02423.15 GAK65497.1 - 0.0043 16.0 0.5 0.082 11.8 0.1 2.4 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Fe-ADH PF00465.19 GAK65497.1 - 0.017 14.0 0.8 0.41 9.4 0.0 3.2 4 0 0 4 4 4 0 Iron-containing alcohol dehydrogenase SURF6 PF04935.12 GAK65498.1 - 2e-46 158.3 37.3 2e-46 158.3 37.3 3.3 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 GAK65498.1 - 4.9e-17 62.3 5.7 4.9e-17 62.3 5.7 6.4 7 1 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 WD40 PF00400.32 GAK65499.1 - 6.1e-60 197.8 24.4 7.5e-09 36.1 0.0 9.2 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK65499.1 - 2.5e-17 63.0 2.0 0.00056 20.1 0.0 5.5 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 GAK65499.1 - 5e-05 23.7 0.3 0.00013 22.5 0.3 1.7 1 1 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 GAK65499.1 - 8.7e-05 21.6 0.0 0.08 11.9 0.0 3.5 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAK65499.1 - 0.00027 20.9 0.0 0.0016 18.4 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAK65499.1 - 0.00062 18.5 4.5 0.29 9.7 0.1 4.3 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 GAK65499.1 - 0.03 14.0 0.1 11 5.8 0.1 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 GAK65499.1 - 0.044 13.7 1.4 1.5 8.8 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 GAK65499.1 - 0.047 13.0 0.3 4 6.7 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 GAK65499.1 - 0.2 9.9 0.0 0.69 8.2 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PBP1_TM PF14812.6 GAK65499.1 - 1.7 9.1 7.3 20 5.7 3.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAP2 PF01569.21 GAK65500.1 - 1.7e-20 73.2 3.7 5.1e-20 71.6 3.7 1.9 1 0 0 1 1 1 1 PAP2 superfamily TRAM_LAG1_CLN8 PF03798.16 GAK65501.1 - 1.8e-44 151.9 21.9 1.8e-44 151.9 21.9 2.6 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 GAK65501.1 - 9.5e-08 31.6 0.0 9.5e-08 31.6 0.0 3.1 3 1 0 3 3 3 1 TRAM1-like protein MFS_1 PF07690.16 GAK65502.1 - 1.3e-30 106.5 24.6 2.1e-30 105.8 24.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAK65505.1 - 7.3e-30 103.9 0.0 1.4e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65505.1 - 7.4e-10 38.8 8.8 1.2e-09 38.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CbiK PF06180.11 GAK65506.1 - 0.16 11.3 0.0 0.93 8.8 0.0 1.9 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) GMC_oxred_N PF00732.19 GAK65507.1 - 2.4e-56 191.3 0.0 3.1e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK65507.1 - 6.6e-36 124.0 0.1 1.4e-35 122.9 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAK65507.1 - 5.7e-05 22.4 0.6 0.094 11.8 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAK65507.1 - 0.0015 17.8 0.2 0.0029 16.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAK65507.1 - 0.0016 17.6 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAK65507.1 - 0.012 15.8 0.3 0.044 14.0 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK65507.1 - 0.027 14.1 3.4 0.11 12.1 3.8 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAK65507.1 - 0.028 13.1 0.4 4.9 5.7 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 GAK65507.1 - 0.037 13.3 0.2 0.57 9.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 GAK65509.1 - 3.8e-14 53.7 0.0 1.6e-13 51.7 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAK65509.1 - 0.00051 20.3 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Npa1 PF11707.8 GAK65510.1 - 1.7e-107 359.7 0.0 4.6e-107 358.3 0.0 1.8 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 GAK65510.1 - 8.4e-52 175.7 0.2 2.6e-51 174.1 0.2 1.9 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Phos_pyr_kin PF08543.12 GAK65511.1 - 6.9e-73 245.0 0.0 5.4e-55 186.4 0.0 3.0 2 1 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 GAK65511.1 - 7e-37 127.3 0.1 2.1e-36 125.7 0.1 1.8 1 0 0 1 1 1 1 TENA/THI-4/PQQC family MFS_1 PF07690.16 GAK65511.1 - 3.8e-26 91.9 28.2 7.7e-26 90.9 23.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK65511.1 - 9.2e-08 31.4 4.6 1.9e-07 30.3 4.6 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter HK PF02110.15 GAK65511.1 - 0.19 11.1 0.1 19 4.6 0.0 2.3 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Zn_clus PF00172.18 GAK65514.1 - 0.00055 20.0 8.9 0.001 19.1 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bul1_C PF04426.12 GAK65514.1 - 0.85 9.0 3.1 0.4 10.0 0.1 2.1 2 1 0 2 2 2 0 Bul1 C terminus SET PF00856.28 GAK65515.1 - 2.9e-14 53.8 8.8 5.8e-14 52.8 2.8 3.3 2 2 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAK65515.1 - 1.4e-07 32.2 0.1 8.1e-07 29.8 0.0 2.3 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding RRN3 PF05327.11 GAK65515.1 - 0.42 9.1 15.8 0.68 8.4 15.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BSP_II PF05432.11 GAK65515.1 - 0.79 9.4 22.4 0.16 11.7 16.4 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 GAK65515.1 - 0.98 7.6 25.7 2.2 6.4 25.7 1.5 1 0 0 1 1 1 0 Nop14-like family Steroid_dh PF02544.16 GAK65516.1 - 2.5e-34 118.4 5.1 3.4e-34 118.0 5.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 GAK65516.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 GAK65516.1 - 0.0015 18.1 0.1 0.0022 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 GAK65516.1 - 0.0057 17.0 1.2 0.0095 16.3 0.3 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAK65516.1 - 0.024 15.0 1.4 0.17 12.3 0.4 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase Ubiquitin_2 PF14560.6 GAK65516.1 - 0.071 13.6 0.1 0.16 12.5 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain YukD PF08817.10 GAK65516.1 - 0.11 13.1 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD UAE_UbL PF14732.6 GAK65516.1 - 0.16 12.6 0.1 0.31 11.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Glyco_H_20C_C PF18088.1 GAK65517.1 - 2.3e-34 118.9 0.0 1.6e-33 116.2 0.0 2.1 2 0 0 2 2 2 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 GAK65517.1 - 1.2e-11 44.6 0.0 7.2e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain MMS19_N PF14500.6 GAK65518.1 - 1.5e-68 231.2 0.0 9.5e-67 225.3 0.0 3.6 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 GAK65518.1 - 4e-58 197.5 0.4 1.6e-57 195.6 0.4 2.1 1 1 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 GAK65518.1 - 0.12 12.7 7.0 18 5.9 0.1 6.1 6 0 0 6 6 6 0 HEAT repeat Arm PF00514.23 GAK65518.1 - 0.12 12.4 1.7 25 5.1 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAK65518.1 - 0.14 12.5 12.8 3.7 8.0 0.1 6.1 5 1 0 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 GAK65518.1 - 0.37 11.4 14.0 40 4.9 0.4 7.3 6 1 1 7 7 7 0 HEAT-like repeat SR-25 PF10500.9 GAK65518.1 - 1.8 8.2 3.2 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AT_hook PF02178.19 GAK65519.1 - 0.0022 17.6 11.4 0.078 12.9 2.6 3.3 2 0 0 2 2 2 2 AT hook motif Mobilization_B PF17511.2 GAK65520.1 - 0.13 12.7 0.5 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 Mobilization protein B Aminotran_5 PF00266.19 GAK65521.1 - 1.6e-25 89.9 0.0 3.2e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.17 GAK65521.1 - 1.4e-20 73.6 0.0 3.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAK65521.1 - 2.8e-20 72.4 0.0 5.8e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain TetR_N PF00440.23 GAK65521.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family LacI PF00356.21 GAK65521.1 - 0.15 11.9 0.1 0.51 10.2 0.1 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Peptidase_S49 PF01343.18 GAK65522.1 - 3.1e-48 163.6 0.0 7.1e-27 94.2 0.0 3.0 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.23 GAK65522.1 - 2.1e-05 24.5 0.0 0.00053 19.9 0.0 2.6 2 0 0 2 2 2 1 Clp protease SDH_sah PF01972.16 GAK65522.1 - 0.019 14.0 0.0 0.062 12.3 0.0 1.8 2 0 0 2 2 2 0 Serine dehydrogenase proteinase CHCH PF06747.13 GAK65523.1 - 5.4e-08 32.8 4.2 9.8e-08 31.9 4.2 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 GAK65523.1 - 0.00022 21.6 2.8 0.00071 19.9 2.8 1.9 1 0 0 1 1 1 1 GCK domain Sec6 PF06046.13 GAK65524.1 - 5.6e-166 553.3 0.0 7.1e-166 552.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 NPV_P10 PF05531.12 GAK65524.1 - 0.063 13.8 1.1 0.39 11.2 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Vps53_N PF04100.12 GAK65524.1 - 0.83 8.6 3.9 12 4.8 0.1 2.7 2 1 0 2 2 2 0 Vps53-like, N-terminal Fungal_trans PF04082.18 GAK65525.1 - 1.5e-24 86.4 0.0 3.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65525.1 - 5.6e-07 29.6 7.6 9e-07 28.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 GAK65527.1 - 1.1e-34 119.9 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 GAK65527.1 - 1.5e-22 79.9 0.0 1.5e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 NAD synthase MFS_1 PF07690.16 GAK65528.1 - 1.1e-28 100.2 27.9 1.1e-28 100.2 27.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK65528.1 - 1.2e-10 40.9 2.0 1.2e-10 40.9 2.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4385 PF14328.6 GAK65529.1 - 3.1e-63 212.2 0.4 5.5e-63 211.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) GMC_oxred_N PF00732.19 GAK65530.1 - 5.9e-53 180.2 3.8 3.7e-52 177.5 3.8 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK65530.1 - 1.4e-29 103.5 0.0 2.5e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAK65530.1 - 6.3e-09 35.4 1.0 0.0013 17.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAK65530.1 - 3.1e-05 24.1 0.1 9.7e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Endotoxin_mid PF09131.10 GAK65530.1 - 6.5e-05 22.7 0.4 0.00016 21.4 0.4 1.6 1 0 0 1 1 1 1 Bacillus thuringiensis delta-Endotoxin, middle domain Lycopene_cycl PF05834.12 GAK65530.1 - 7.9e-05 21.9 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAK65530.1 - 0.0001 22.0 1.5 0.00072 19.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK65530.1 - 0.00039 19.8 0.6 0.0061 15.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK65530.1 - 0.0086 15.4 0.0 0.035 13.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK65530.1 - 0.024 13.9 0.4 0.078 12.2 0.1 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 GAK65530.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 GAK65530.1 - 0.14 12.5 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain RNA_pol_A_bac PF01000.26 GAK65531.1 - 4.7e-27 94.6 0.0 1.7e-26 92.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAK65531.1 - 6.6e-18 63.9 0.0 9.3e-18 63.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MIF4G PF02854.19 GAK65532.1 - 2e-47 161.6 0.0 3e-26 92.4 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 GAK65532.1 - 1.1e-23 84.4 1.0 1.1e-23 84.4 1.0 3.0 2 0 0 2 2 2 1 Up-frameshift suppressor 2 SAC3_GANP PF03399.16 GAK65534.1 - 4.3e-100 334.9 0.0 6.7e-100 334.2 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAK65534.1 - 0.0057 16.6 0.5 0.12 12.3 0.0 2.4 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family MFS_1 PF07690.16 GAK65535.1 - 1.1e-33 116.6 51.1 3e-28 98.8 31.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.8 GAK65535.1 - 6.8 7.0 11.9 0.91 9.8 0.3 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF2096 PF09869.9 GAK65537.1 - 0.02 15.0 0.2 0.27 11.3 0.0 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) DivIC PF04977.15 GAK65537.1 - 8.2 6.3 8.0 25 4.8 2.1 3.0 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 GAK65538.1 - 5.5e-09 36.0 13.7 9.4e-09 35.3 13.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAK65538.1 - 4.9e-08 32.9 9.0 4.9e-08 32.9 9.0 2.2 1 1 1 2 2 2 1 Basic region leucine zipper HAUS4 PF14735.6 GAK65538.1 - 0.0055 16.4 1.5 0.012 15.3 1.5 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 TfuA PF07812.12 GAK65538.1 - 0.045 13.5 0.2 0.15 11.8 0.2 1.9 1 0 0 1 1 1 0 TfuA-like protein TSC22 PF01166.18 GAK65538.1 - 0.2 12.0 1.3 0.38 11.1 1.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family MCPVI PF02993.14 GAK65538.1 - 0.41 10.5 10.3 1.2 9.0 1.3 2.5 2 0 0 2 2 2 0 Minor capsid protein VI FAM176 PF14851.6 GAK65538.1 - 1.4 8.6 10.4 4.1 7.1 10.4 1.8 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 GAK65538.1 - 8.4 4.6 16.9 12 4.0 16.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S8e PF01201.22 GAK65541.1 - 2.6e-55 186.3 1.0 3.1e-55 186.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e tRNA-synt_1 PF00133.22 GAK65542.1 - 1.4e-220 733.6 0.0 1.5e-219 730.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAK65542.1 - 2.8e-37 128.0 1.0 5.6e-37 127.0 0.6 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAK65542.1 - 1.9e-15 56.5 0.2 3.4e-07 29.4 0.1 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAK65542.1 - 1.6e-11 44.1 3.5 2.2e-07 30.6 0.1 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAK65542.1 - 0.0055 16.1 0.0 0.62 9.3 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 GAK65542.1 - 0.13 11.6 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.21 GAK65542.1 - 0.17 10.7 0.2 1.8 7.4 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Val_tRNA-synt_C PF10458.9 GAK65542.1 - 1.1 9.6 9.9 0.059 13.7 2.7 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Methyltransf_23 PF13489.6 GAK65543.1 - 8.8e-11 41.9 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK65543.1 - 4.8e-06 27.1 0.0 7.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK65543.1 - 1.7e-05 25.5 0.0 3.8e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK65543.1 - 1.7e-05 24.6 0.0 5.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK65543.1 - 0.0036 18.0 0.0 0.0062 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 GAK65543.1 - 0.0047 16.7 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Fungal_trans PF04082.18 GAK65544.1 - 2.4e-11 43.2 0.0 5.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65544.1 - 1.2e-05 25.4 12.7 2.1e-05 24.5 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 GAK65545.1 - 3.2e-41 141.7 0.0 5e-41 141.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAK65545.1 - 0.00034 19.3 0.0 0.00068 18.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAK65545.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pectinesterase PF01095.19 GAK65546.1 - 6.6e-33 113.7 0.2 4e-31 107.9 0.2 2.1 1 1 0 1 1 1 1 Pectinesterase NAD_binding_10 PF13460.6 GAK65547.1 - 1.3e-30 106.7 0.0 2e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAK65547.1 - 0.0002 20.9 0.0 0.00027 20.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAK65547.1 - 0.0045 16.6 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 GAK65547.1 - 0.19 10.9 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein F-box-like PF12937.7 GAK65548.1 - 4.5e-13 48.9 0.2 9.2e-13 47.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK65548.1 - 5.5e-10 38.9 0.2 2e-09 37.1 0.2 1.9 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 GAK65548.1 - 6.9e-10 39.4 0.5 0.00034 21.4 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat HAD_2 PF13419.6 GAK65548.1 - 1.4e-06 28.5 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAK65548.1 - 0.06 13.6 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nup160 PF11715.8 GAK65548.1 - 0.11 11.1 0.1 1.3 7.6 0.0 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 TB2_DP1_HVA22 PF03134.19 GAK65549.1 - 2.3e-28 97.9 7.0 2.3e-28 97.9 7.0 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family CENP-I PF07778.11 GAK65550.1 - 8.3e-08 31.4 1.4 2.5e-07 29.8 0.7 2.1 2 0 0 2 2 2 1 Mis6 Nop14 PF04147.12 GAK65551.1 - 2.8 6.0 15.8 4.6 5.3 15.8 1.2 1 0 0 1 1 1 0 Nop14-like family AA_permease_2 PF13520.6 GAK65552.1 - 3.6e-57 194.1 55.9 4.3e-57 193.8 55.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAK65552.1 - 1e-18 67.2 50.8 1.4e-18 66.8 50.8 1.1 1 0 0 1 1 1 1 Amino acid permease Glycophorin_A PF01102.18 GAK65552.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.9 1 0 0 1 1 1 0 Glycophorin A Aldedh PF00171.22 GAK65553.1 - 8.2e-177 588.3 0.2 9.3e-177 588.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.20 GAK65554.1 - 1.5e-152 508.3 0.3 1.8e-152 508.0 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAK65554.1 - 2.4e-13 50.4 0.0 4.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 GAK65554.1 - 0.00031 20.9 0.0 0.00098 19.3 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Zn_clus PF00172.18 GAK65555.1 - 6e-05 23.1 10.1 0.0001 22.4 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain QCR10 PF09796.9 GAK65556.1 - 7.7e-22 77.1 0.4 1.2e-21 76.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Gln-synt_C PF00120.24 GAK65557.1 - 7.9e-17 61.3 0.0 2.1e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GAK65557.1 - 5.4e-12 45.3 0.0 9.3e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF676 PF05057.14 GAK65558.1 - 8.6e-06 25.4 0.0 1.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) T-box_assoc PF16176.5 GAK65558.1 - 0.099 12.7 10.3 0.021 14.9 3.0 3.0 3 0 0 3 3 3 0 T-box transcription factor-associated LCAT PF02450.15 GAK65558.1 - 0.18 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_L3 PF00297.22 GAK65559.1 - 3.2e-19 69.1 2.8 8.8e-17 61.1 1.9 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Pam16 PF03656.13 GAK65560.1 - 1.2e-18 67.3 0.5 4e-17 62.4 0.5 2.2 1 1 0 1 1 1 1 Pam16 Arg_decarbox_C PF17944.1 GAK65560.1 - 0.16 12.5 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension tRNA-synt_1g PF09334.11 GAK65561.1 - 1.9e-150 501.0 0.0 2.5e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAK65561.1 - 9.5e-07 27.4 0.5 0.00026 19.4 0.0 3.6 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAK65561.1 - 0.00062 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA HypA PF01155.19 GAK65561.1 - 0.031 14.3 4.4 1.6 8.8 0.2 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 GAK65561.1 - 1.9 8.6 10.0 1.2 9.2 6.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 GAK65561.1 - 2.1 8.4 7.0 6.5 6.8 6.8 1.9 1 1 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 GAK65561.1 - 9.5 6.4 9.2 6.6 6.9 1.5 2.6 2 0 0 2 2 2 0 Zinc ribbon domain F-box-like PF12937.7 GAK65562.1 - 0.043 13.7 0.3 0.085 12.8 0.3 1.5 1 0 0 1 1 1 0 F-box-like Ribosomal_L14 PF00238.19 GAK65563.1 - 1.7e-33 115.3 0.0 2.3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e F-box-like PF12937.7 GAK65564.1 - 0.027 14.3 0.4 0.082 12.8 0.4 1.9 1 0 0 1 1 1 0 F-box-like zf-C2H2_aberr PF17017.5 GAK65566.1 - 4.2e-06 27.0 2.5 0.056 13.6 0.1 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 GAK65566.1 - 0.019 15.4 10.6 0.12 12.8 0.6 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3109 PF11307.8 GAK65566.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) zf-H2C2_2 PF13465.6 GAK65566.1 - 0.59 10.7 3.5 0.98 10.0 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAK65566.1 - 1.4 9.9 13.9 2 9.4 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger OTCace PF00185.24 GAK65567.1 - 8.8e-46 155.8 0.0 1.5e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 GAK65567.1 - 6e-44 149.6 0.1 1e-43 148.9 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Aminotran_1_2 PF00155.21 GAK65567.1 - 9.9e-17 61.1 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II BAR_2 PF10455.9 GAK65568.1 - 1e-45 156.1 0.6 1.7e-45 155.4 0.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 GAK65568.1 - 5.8e-21 75.2 6.0 2.3e-16 60.2 3.0 2.1 2 0 0 2 2 2 2 BAR domain BAR_3 PF16746.5 GAK65568.1 - 0.015 15.0 2.1 0.031 14.0 0.4 2.0 2 0 0 2 2 2 0 BAR domain of APPL family Seryl_tRNA_N PF02403.22 GAK65568.1 - 0.043 14.1 5.1 19 5.5 0.0 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 GAK65568.1 - 0.061 13.8 2.8 0.12 12.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 GIDA_assoc PF13932.6 GAK65568.1 - 0.074 13.2 2.2 0.33 11.1 0.4 2.1 2 0 0 2 2 2 0 GidA associated domain Sec8_exocyst PF04048.14 GAK65568.1 - 0.081 12.8 2.5 0.68 9.8 0.8 2.9 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain PCRF PF03462.18 GAK65568.1 - 0.12 12.2 4.5 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 PCRF domain DUF3450 PF11932.8 GAK65568.1 - 0.16 11.2 10.1 5.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Uds1 PF15456.6 GAK65568.1 - 0.21 11.7 7.9 0.45 10.7 0.0 3.0 2 1 0 2 2 2 0 Up-regulated During Septation TMF_DNA_bd PF12329.8 GAK65568.1 - 0.43 10.6 7.4 2.6 8.1 0.1 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.21 GAK65568.1 - 1.9 9.0 7.1 2.6 8.6 0.2 3.0 2 2 0 2 2 2 0 Spectrin repeat ATG16 PF08614.11 GAK65568.1 - 4.3 7.5 12.2 1.1 9.4 4.8 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HSCB_C PF07743.13 GAK65568.1 - 6.2 7.4 10.4 4.2 7.9 3.8 3.3 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain DUF3040 PF11239.8 GAK65569.1 - 0.22 11.8 0.6 0.77 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF4451 PF14616.6 GAK65570.1 - 1.4e-30 106.0 0.5 2.3e-30 105.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) CMS1 PF14617.6 GAK65571.1 - 1.5e-52 178.4 7.3 1.2e-25 90.4 3.6 2.3 1 1 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit Rrn6 PF10214.9 GAK65571.1 - 0.55 8.6 6.7 0.81 8.1 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Med19 PF10278.9 GAK65571.1 - 0.9 9.4 8.7 0.67 9.9 5.3 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 ING PF12998.7 GAK65572.1 - 5.6e-11 42.9 0.4 7.5e-11 42.5 0.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAK65572.1 - 2.7e-06 27.2 7.0 4.1e-06 26.6 7.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAK65572.1 - 0.038 13.5 2.0 0.069 12.7 2.0 1.4 1 0 0 1 1 1 0 PHD-finger Med4 PF10018.9 GAK65572.1 - 0.074 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Tmemb_cc2 PF10267.9 GAK65572.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CPSase_L_D2 PF02786.17 GAK65573.1 - 3.5e-113 376.3 0.1 9.3e-83 276.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAK65573.1 - 2.2e-47 160.1 0.0 4.6e-47 159.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 GAK65573.1 - 2.1e-45 154.4 0.0 5.3e-45 153.1 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 GAK65573.1 - 9.7e-45 152.7 0.0 1.1e-43 149.3 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 GAK65573.1 - 6.3e-41 139.6 0.2 1.6e-40 138.3 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 GAK65573.1 - 2e-29 102.7 0.0 4.9e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp PF02222.22 GAK65573.1 - 1.6e-17 63.6 0.0 1.1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAK65573.1 - 7e-17 61.6 0.1 3e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAK65573.1 - 2e-10 40.5 0.1 7e-05 22.6 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 GAK65573.1 - 2.4e-09 37.2 0.0 8.1e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.13 GAK65573.1 - 1.8e-06 27.8 0.1 0.00019 21.2 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 GAK65573.1 - 7.6e-05 22.8 0.1 0.12 12.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 GAK65573.1 - 0.00058 19.7 0.0 0.037 13.8 0.0 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CRAL_TRIO PF00650.20 GAK65574.1 - 3.2e-24 85.4 0.0 4.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAK65574.1 - 9e-07 29.0 0.4 2.6e-06 27.5 0.1 1.9 1 1 1 2 2 2 1 CRAL/TRIO, N-terminal domain NADHdh_A3 PF14987.6 GAK65575.1 - 0.018 15.3 0.5 0.023 15.0 0.5 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 AmpE PF17113.5 GAK65575.1 - 0.12 11.7 0.1 0.12 11.7 0.1 1.0 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE ADH_N_2 PF16884.5 GAK65577.1 - 2.4e-29 101.4 0.1 7.8e-29 99.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAK65577.1 - 6.8e-24 84.3 0.2 1.4e-23 83.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK65577.1 - 1.3e-08 35.9 0.0 7.7e-08 33.5 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAK65577.1 - 1.3e-05 24.8 0.1 2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase PNP_UDP_1 PF01048.20 GAK65578.1 - 1.3e-24 86.7 0.1 1.8e-24 86.3 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Band_7 PF01145.25 GAK65579.1 - 4.8e-23 82.1 6.3 1.2e-22 80.8 6.0 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 GAK65579.1 - 0.0021 17.2 3.6 0.0026 16.9 3.6 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial AAA_lid_4 PF17864.1 GAK65579.1 - 0.081 12.7 4.2 0.11 12.3 0.2 2.7 1 1 2 3 3 3 0 RuvB AAA lid domain FLILHELTA PF10306.9 GAK65580.1 - 2e-17 63.3 0.0 5.2e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA tRNA-synt_2b PF00587.25 GAK65580.1 - 1.4e-16 61.0 0.4 1.1e-15 58.1 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1279 PF06916.13 GAK65580.1 - 0.042 14.4 0.0 0.091 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DUF4618 PF15397.6 GAK65580.1 - 0.21 11.0 6.0 0.033 13.6 2.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) WDCP PF15390.6 GAK65580.1 - 0.4 9.0 2.1 0.63 8.3 2.1 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family FapA PF03961.13 GAK65580.1 - 0.67 8.5 1.9 1.2 7.7 1.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DNA_topoisoIV PF00521.20 GAK65581.1 - 5.4e-130 434.1 0.1 1.4e-129 432.7 0.0 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAK65581.1 - 3e-53 179.5 1.0 3e-53 179.5 1.0 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAK65581.1 - 5.2e-28 97.7 1.8 1e-27 96.8 1.8 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAK65581.1 - 1.5e-14 54.5 0.0 3.8e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAK65581.1 - 7.9e-09 35.7 0.0 3.1e-08 33.8 0.0 2.1 1 0 0 1 1 1 1 Toprim domain RabGAP-TBC PF00566.18 GAK65582.1 - 2.1e-58 197.5 0.3 3.3e-58 196.9 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 GAK65582.1 - 0.14 12.3 2.9 0.23 11.6 0.7 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Gemini_AL2 PF01440.16 GAK65582.1 - 0.19 12.2 1.2 0.5 10.8 1.2 1.7 1 0 0 1 1 1 0 Geminivirus AL2 protein Asn_synthase PF00733.21 GAK65583.1 - 1.4e-19 70.9 1.0 8.7e-08 32.2 0.1 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 GAK65583.1 - 6e-10 39.1 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAK65583.1 - 9.3e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Chs7 PF12271.8 GAK65584.1 - 1.8e-114 381.9 16.9 2.1e-114 381.7 16.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone WD40 PF00400.32 GAK65585.1 - 4.4e-31 106.5 13.9 9e-06 26.3 0.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 GAK65585.1 - 2.6e-09 36.3 0.3 0.0003 19.6 0.0 4.1 4 1 0 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAK65585.1 - 4.6e-05 23.6 0.0 5.1 7.5 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CENP-F_leu_zip PF10473.9 GAK65585.1 - 0.077 13.0 5.2 0.16 12.0 5.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med3 PF11593.8 GAK65586.1 - 5.4 6.1 9.9 8.5 5.4 9.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_22 PF13401.6 GAK65587.1 - 4.7e-18 65.8 0.9 1.2e-17 64.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAK65587.1 - 1.7e-09 38.2 0.0 4.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAK65587.1 - 7.5e-09 35.7 1.2 2.2e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain TniB PF05621.11 GAK65587.1 - 1.1e-08 34.7 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 GAK65587.1 - 2.3e-07 31.4 0.4 2.3e-07 31.4 0.4 3.4 3 2 0 3 3 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 GAK65587.1 - 0.00038 20.5 0.1 0.00087 19.4 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain NB-ARC PF00931.22 GAK65587.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 GAK65587.1 - 0.011 15.6 0.0 0.076 12.9 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAK65587.1 - 0.022 14.9 2.8 0.034 14.3 0.0 2.7 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 GAK65587.1 - 0.028 14.1 0.1 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_assoc_2 PF16193.5 GAK65587.1 - 0.03 14.6 1.0 0.15 12.5 1.0 2.2 1 0 0 1 1 1 0 AAA C-terminal domain AAA_19 PF13245.6 GAK65587.1 - 0.035 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain FAD_SOX PF18371.1 GAK65587.1 - 0.08 13.3 0.0 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Spt20 PF12090.8 GAK65587.1 - 0.15 11.7 1.3 0.25 10.9 1.3 1.3 1 0 0 1 1 1 0 Spt20 family DUF2075 PF09848.9 GAK65587.1 - 0.18 11.0 0.0 0.48 9.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KH_1 PF00013.29 GAK65588.1 - 0.017 15.0 0.4 0.037 13.9 0.4 1.6 1 0 0 1 1 1 0 KH domain KH_8 PF17903.1 GAK65588.1 - 0.043 13.9 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Krr1 KH1 domain RRM_1 PF00076.22 GAK65589.1 - 3.4e-76 251.0 0.4 1.1e-18 66.9 0.4 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAK65589.1 - 9.8e-26 89.7 0.5 4.9e-25 87.5 0.6 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAK65589.1 - 8.9e-09 35.0 0.0 0.14 11.7 0.0 4.2 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YflT PF11181.8 GAK65589.1 - 0.0012 19.3 0.8 0.075 13.6 0.2 2.6 2 0 0 2 2 2 1 Heat induced stress protein YflT RRM_7 PF16367.5 GAK65589.1 - 0.003 17.7 0.2 15 5.8 0.1 4.2 4 2 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 GAK65589.1 - 0.02 14.9 3.7 0.72 9.9 1.8 3.2 4 0 0 4 4 4 0 RNA binding motif Nup35_RRM_2 PF14605.6 GAK65589.1 - 0.024 14.6 0.3 29 4.7 0.0 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 GAK65589.1 - 0.069 12.8 1.0 18 5.1 0.2 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain GrpE PF01025.19 GAK65590.1 - 1.1e-44 152.0 0.1 1.4e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 GrpE DUF4201 PF13870.6 GAK65590.1 - 0.0092 15.7 0.7 0.013 15.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Choline_transpo PF04515.12 GAK65591.1 - 5.9e-58 196.6 16.5 7.2e-57 193.0 13.0 2.9 2 1 0 2 2 2 2 Plasma-membrane choline transporter PCI PF01399.27 GAK65592.1 - 0.00086 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain ParB PF08775.10 GAK65592.1 - 0.016 15.7 3.0 0.018 15.5 1.8 1.6 2 0 0 2 2 2 0 ParB family Spc7 PF08317.11 GAK65592.1 - 0.032 13.1 4.6 0.052 12.4 4.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 GAK65592.1 - 0.049 13.7 1.1 0.096 12.8 1.1 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 VIR_N PF15912.5 GAK65592.1 - 7 6.2 7.0 19 4.8 0.0 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Pkinase PF00069.25 GAK65593.1 - 4.8e-57 193.3 0.0 2.1e-56 191.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK65593.1 - 5.4e-28 98.0 0.0 1.9e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK65593.1 - 1.5e-06 27.7 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAK65593.1 - 0.028 14.4 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAK65593.1 - 0.063 12.3 0.1 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Adap_comp_sub PF00928.21 GAK65594.1 - 2.9e-92 308.8 0.0 6.1e-92 307.7 0.0 1.6 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Oxysterol_BP PF01237.18 GAK65594.1 - 2.7e-65 220.6 0.2 2.2e-58 197.9 0.0 2.3 1 1 1 2 2 2 2 Oxysterol-binding protein Clat_adaptor_s PF01217.20 GAK65594.1 - 2.1e-06 27.7 0.2 3.5e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PA_decarbox PF05870.11 GAK65595.1 - 1.1e-08 34.8 0.1 1.5e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) ParA PF10609.9 GAK65596.1 - 8.3e-88 294.0 0.0 1e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 GAK65596.1 - 2.1e-05 23.8 1.2 0.00015 21.0 0.3 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase CbiA PF01656.23 GAK65596.1 - 4.6e-05 23.5 0.6 0.00025 21.1 0.8 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAK65596.1 - 0.00018 21.5 0.0 0.059 13.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain zf-C4_ClpX PF06689.13 GAK65596.1 - 0.0021 17.9 0.6 0.004 17.0 0.6 1.4 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA_26 PF13500.6 GAK65596.1 - 0.0076 16.1 0.1 0.79 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 GAK65596.1 - 0.059 12.7 0.0 0.16 11.2 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ AAA_16 PF13191.6 GAK65596.1 - 0.089 13.2 0.2 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 GAK65596.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain LapA_dom PF06305.11 GAK65597.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EMP24_GP25L PF01105.24 GAK65599.1 - 5.3e-46 156.9 0.0 6.1e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Voltage_CLC PF00654.20 GAK65600.1 - 2.6e-90 303.2 29.3 3.8e-90 302.7 29.3 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel Pro_isomerase PF00160.21 GAK65600.1 - 9e-32 110.5 0.0 1.6e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 GAK65600.1 - 2.7e-15 55.9 0.0 6.7e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.28 GAK65600.1 - 1.3e-07 31.9 0.0 1.6e-05 25.3 0.1 2.9 2 0 0 2 2 2 1 CBS domain RNA_pol_Rpc4 PF05132.14 GAK65601.1 - 0.058 13.8 2.0 0.079 13.4 2.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 LRRFIP PF09738.9 GAK65601.1 - 0.24 10.9 3.7 0.27 10.7 3.7 1.1 1 0 0 1 1 1 0 LRRFIP family Sec3_C PF09763.9 GAK65601.1 - 4.5 5.5 4.8 5.1 5.4 4.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Linker_histone PF00538.19 GAK65602.1 - 1.2e-18 67.3 0.2 3.7e-18 65.7 0.2 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Baculo_11_kDa PF06143.11 GAK65602.1 - 0.028 14.0 0.4 0.055 13.0 0.4 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.6 GAK65602.1 - 0.033 15.1 0.1 0.085 13.7 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BatD PF13584.6 GAK65602.1 - 0.066 12.0 6.1 0.088 11.6 6.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance Orf78 PF06024.12 GAK65602.1 - 0.073 13.4 1.1 0.18 12.2 0.8 1.8 1 1 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 GAK65602.1 - 0.1 12.8 0.5 0.22 11.7 0.5 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RIFIN PF02009.16 GAK65602.1 - 0.31 10.9 9.9 0.017 15.0 3.8 2.0 2 1 1 3 3 3 0 Rifin PrgH PF09480.10 GAK65602.1 - 0.42 9.9 1.7 0.63 9.3 0.8 1.8 2 0 0 2 2 2 0 Type III secretion system protein PrgH-EprH (PrgH) Stevor PF17410.2 GAK65602.1 - 1.1 8.7 4.1 0.95 9.0 1.5 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame MutL_C PF08676.11 GAK65603.1 - 1.3e-08 34.8 0.1 2.4e-07 30.6 0.0 2.3 1 1 1 2 2 2 1 MutL C terminal dimerisation domain DUF1353 PF07087.11 GAK65603.1 - 0.0035 17.0 0.0 0.0087 15.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1353) FIST_C PF10442.9 GAK65603.1 - 0.17 11.9 0.8 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 FIST C domain PEN-2 PF10251.9 GAK65606.1 - 0.043 14.2 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Spt20 PF12090.8 GAK65606.1 - 0.95 9.0 5.5 2.5 7.7 5.5 1.6 1 0 0 1 1 1 0 Spt20 family PCI PF01399.27 GAK65607.1 - 5e-09 36.6 0.0 9.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain TIP120 PF08623.10 GAK65608.1 - 1.2e-52 178.1 2.8 1.9e-50 170.9 0.1 4.0 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 GAK65608.1 - 5.7e-15 55.5 28.5 3.6e-05 24.1 0.5 9.6 6 5 2 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 GAK65608.1 - 1.1e-11 44.9 28.8 0.58 10.7 0.2 11.1 12 0 0 12 12 12 5 HEAT-like repeat HEAT PF02985.22 GAK65608.1 - 4.5e-10 38.9 34.2 0.5 10.8 0.2 13.9 15 0 0 15 15 15 4 HEAT repeat Cnd1 PF12717.7 GAK65608.1 - 0.00014 22.0 9.4 0.19 11.7 1.9 5.0 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Telomere_reg-2 PF10193.9 GAK65608.1 - 0.0011 19.4 1.2 0.24 11.9 0.0 4.1 4 1 0 4 4 4 1 Telomere length regulation protein Cnd3 PF12719.7 GAK65608.1 - 0.002 17.4 5.4 0.033 13.4 0.1 4.1 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain RNA_pol_3_Rpc31 PF11705.8 GAK65608.1 - 3.7 7.7 10.0 6.1 7.0 10.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PHO4 PF01384.20 GAK65609.1 - 7.8e-116 386.8 16.3 9e-116 386.6 16.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.16 GAK65610.1 - 3.9e-31 108.3 42.9 4.7e-29 101.4 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5357 PF17310.2 GAK65610.1 - 0.77 8.3 4.8 4 5.9 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5357) LacI PF00356.21 GAK65612.1 - 0.063 13.1 0.7 0.24 11.2 0.7 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Cation_ATPase_C PF00689.21 GAK65613.1 - 3.4e-47 160.5 6.3 3.4e-47 160.5 6.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAK65613.1 - 4.1e-38 130.7 0.1 4.1e-38 130.7 0.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAK65613.1 - 1.7e-20 72.9 0.1 3.8e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAK65613.1 - 4.2e-17 63.1 6.3 1.5e-16 61.4 6.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK65613.1 - 5e-08 32.5 0.4 1.8e-06 27.5 0.1 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAK65613.1 - 0.00072 19.4 0.2 0.021 14.6 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phosphodiest PF01663.22 GAK65615.1 - 9.1e-09 35.4 1.2 1.7e-08 34.5 1.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 GAK65615.1 - 0.027 13.8 1.9 0.049 13.0 1.9 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.12 GAK65615.1 - 0.04 14.0 2.7 1.7 8.7 0.2 2.3 2 0 0 2 2 2 0 PglZ domain Sulfatase PF00884.23 GAK65615.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Sulfatase SUR7 PF06687.12 GAK65616.1 - 2.4e-18 66.6 3.7 3.2e-18 66.1 3.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family Ninjurin PF04923.12 GAK65616.1 - 0.052 13.5 0.7 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Ninjurin DUF4407 PF14362.6 GAK65616.1 - 0.14 11.4 1.2 0.2 10.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PMP22_Claudin PF00822.20 GAK65616.1 - 0.18 11.7 3.9 0.53 10.1 3.9 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 GAK65616.1 - 1.2 8.9 7.5 0.44 10.4 3.8 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein Clc-like PF07062.12 GAK65616.1 - 1.9 7.9 8.4 0.11 12.0 2.7 1.7 2 0 0 2 2 2 0 Clc-like DUF4064 PF13273.6 GAK65616.1 - 9.9 6.5 8.7 21 5.5 3.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Ribosomal_S7 PF00177.21 GAK65617.1 - 4.4e-35 120.5 0.8 8.4e-35 119.6 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Myb_DNA-binding PF00249.31 GAK65617.1 - 9.5e-25 86.5 0.0 5.5e-13 48.9 0.1 5.1 5 1 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAK65617.1 - 5.9e-16 58.5 0.0 6.2e-06 26.4 0.0 4.7 4 1 1 5 5 5 3 Myb-like DNA-binding domain ASFV_J13L PF05568.11 GAK65617.1 - 1.8 8.3 6.0 0.33 10.7 0.5 2.5 2 0 0 2 2 2 0 African swine fever virus J13L protein Peptidase_S10 PF00450.22 GAK65618.1 - 3.4e-98 329.8 0.0 4.6e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CN_hydrolase PF00795.22 GAK65619.1 - 2e-21 76.5 0.1 3.9e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase LNS2 PF08235.13 GAK65620.1 - 1.5e-99 332.1 0.0 6.8e-77 258.0 0.0 2.2 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 GAK65620.1 - 5e-29 100.3 0.4 1.8e-18 66.4 0.0 2.6 2 0 0 2 2 2 2 lipin, N-terminal conserved region Lipin_mid PF16876.5 GAK65620.1 - 6.8e-20 71.1 0.0 1.5e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Peptidase_S64 PF08192.11 GAK65621.1 - 6.3 5.2 4.9 9.4 4.6 4.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 IPP-2 PF04979.14 GAK65622.1 - 5.1e-20 72.6 4.4 2e-18 67.4 4.4 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) SWIRM-assoc_2 PF16496.5 GAK65622.1 - 0.0043 16.0 7.1 0.0043 16.0 7.1 1.9 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal PPP4R2 PF09184.11 GAK65622.1 - 0.016 14.8 3.9 0.024 14.2 3.9 1.2 1 0 0 1 1 1 0 PPP4R2 DLIC PF05783.11 GAK65623.1 - 2e-54 185.2 17.2 9.1e-29 100.6 0.0 7.0 4 2 3 7 7 7 6 Dynein light intermediate chain (DLIC) MCM PF00493.23 GAK65623.1 - 0.0037 16.4 0.1 0.0067 15.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 GAK65623.1 - 0.0089 16.4 0.5 0.0089 16.4 0.5 2.7 2 1 1 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAK65623.1 - 0.02 15.0 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK65623.1 - 0.037 13.9 0.4 2.7 7.8 0.3 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF2813 PF11398.8 GAK65623.1 - 0.089 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Pkr1 PF08636.10 GAK65624.1 - 4e-26 90.9 2.7 4.7e-26 90.7 2.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 UPF0154 PF03672.13 GAK65624.1 - 0.0092 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) DUF5317 PF17248.2 GAK65624.1 - 0.012 15.6 0.2 0.014 15.4 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5317) DUF5531 PF17671.1 GAK65624.1 - 0.045 13.6 0.2 0.058 13.3 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5531) PhoR PF11808.8 GAK65624.1 - 0.096 13.1 1.7 2.3 8.7 1.1 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR NR_Repeat PF14046.6 GAK65624.1 - 0.26 11.4 0.9 0.43 10.8 0.9 1.3 1 0 0 1 1 1 0 Nuclear receptor repeat OAD_gamma PF04277.13 GAK65624.1 - 3.5 8.3 5.9 45 4.7 5.9 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF676 PF05057.14 GAK65628.1 - 6.6e-31 107.5 0.0 3.3e-30 105.2 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GAK65628.1 - 0.0013 19.4 6.2 0.018 15.6 6.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAK65628.1 - 0.012 15.1 0.0 0.045 13.3 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family ABC_tran PF00005.27 GAK65629.1 - 3.6e-48 163.5 0.1 1.1e-23 84.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 GAK65629.1 - 8.4e-20 71.2 30.8 2.4e-12 46.6 6.5 2.4 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAK65629.1 - 1e-11 45.2 10.2 0.0002 21.3 0.0 4.4 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAK65629.1 - 7.3e-06 25.6 0.1 0.59 9.5 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK65629.1 - 0.0012 18.6 1.4 0.046 13.5 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 GAK65629.1 - 0.027 14.1 1.9 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 GAK65629.1 - 0.15 12.5 1.1 1.8 9.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 GAK65629.1 - 0.84 9.4 3.2 18 5.0 0.1 2.6 3 0 0 3 3 3 0 MukB N-terminal DUF87 PF01935.17 GAK65629.1 - 0.93 9.5 5.2 3.1 7.8 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain CN_hydrolase PF00795.22 GAK65630.1 - 8.2e-44 149.9 0.0 1.3e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LSM PF01423.22 GAK65632.1 - 3.8e-07 29.7 0.0 5.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAK65632.1 - 0.00057 20.0 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain NMO PF03060.15 GAK65633.1 - 6.3e-53 180.3 0.1 9.6e-53 179.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAK65633.1 - 3.1e-13 49.5 0.8 4.9e-13 48.8 0.8 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAK65633.1 - 8.4e-05 21.8 2.1 0.00014 21.0 2.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Arm-DNA-bind_3 PF13356.6 GAK65634.1 - 0.095 13.1 0.6 0.34 11.3 0.6 1.9 1 0 0 1 1 1 0 Arm DNA-binding domain Semialdhyde_dhC PF02774.18 GAK65635.1 - 0.2 11.7 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain AAA_18 PF13238.6 GAK65636.1 - 7.3e-25 88.0 0.0 1.6e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAK65636.1 - 0.0026 18.0 2.6 0.0043 17.3 1.4 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAK65636.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAK65636.1 - 0.076 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 GAK65636.1 - 0.089 13.2 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 GAK65636.1 - 0.12 12.0 0.0 0.97 9.1 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase KTI12 PF08433.10 GAK65636.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAK65636.1 - 0.22 11.7 0.5 11 6.2 0.2 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 GAK65637.1 - 7.7e-108 360.0 0.5 1.1e-107 359.5 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 GAK65637.1 - 2.4e-08 34.0 0.0 6.7e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK65637.1 - 7.1e-05 22.4 0.6 0.0014 18.2 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAK65637.1 - 0.00012 22.1 0.7 0.0086 16.0 0.6 3.0 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAK65637.1 - 0.002 18.2 5.7 0.14 12.2 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 GAK65637.1 - 0.0026 18.3 7.9 0.41 11.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 GAK65637.1 - 0.0036 16.7 0.1 0.0071 15.7 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.6 GAK65637.1 - 0.0039 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.16 GAK65637.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.6 GAK65637.1 - 0.0063 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK65637.1 - 0.009 16.4 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 GAK65637.1 - 0.013 15.8 2.4 0.12 12.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain IIGP PF05049.13 GAK65637.1 - 0.014 14.5 1.2 0.027 13.6 0.1 2.0 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 GAK65637.1 - 0.017 15.4 1.9 0.04 14.2 0.0 2.4 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 GAK65637.1 - 0.024 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAK65637.1 - 0.037 14.6 0.4 0.13 12.8 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 GAK65637.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAK65637.1 - 0.063 13.6 0.1 0.3 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 GAK65637.1 - 0.082 12.5 0.3 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 Ras family RNA_helicase PF00910.22 GAK65637.1 - 0.088 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 GAK65637.1 - 0.13 12.8 2.5 0.39 11.3 0.0 2.7 2 1 0 3 3 3 0 AAA domain NACHT PF05729.12 GAK65637.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 GAK65637.1 - 4 7.5 7.2 3.6 7.6 0.4 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain TPK_catalytic PF04263.16 GAK65638.1 - 1.4e-29 102.6 0.0 2.4e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 GAK65638.1 - 2.9e-20 71.8 0.0 4.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Lactamase_B_2 PF12706.7 GAK65638.1 - 8e-10 38.6 0.0 2.7e-07 30.3 0.0 3.0 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAK65638.1 - 1.1e-06 28.9 0.0 3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 GAK65638.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Spindle_Spc25 PF08234.12 GAK65639.1 - 1.5e-21 76.4 0.2 3.2e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Cortex-I_coil PF09304.10 GAK65639.1 - 0.0012 19.1 15.6 0.0012 19.1 15.6 1.8 2 0 0 2 2 2 1 Cortexillin I, coiled coil HAUS-augmin3 PF14932.6 GAK65639.1 - 0.0051 16.4 15.3 0.0051 16.4 15.3 1.8 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 HAP1_N PF04849.13 GAK65639.1 - 0.0073 15.6 12.3 0.0073 15.6 12.3 1.5 2 0 0 2 2 2 1 HAP1 N-terminal conserved region CALCOCO1 PF07888.11 GAK65639.1 - 0.041 12.7 22.8 0.072 11.9 22.8 1.3 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 GAK65639.1 - 0.085 11.7 20.1 0.013 14.4 14.1 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF2968 PF11180.8 GAK65639.1 - 0.75 9.4 16.7 0.094 12.3 12.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FapA PF03961.13 GAK65639.1 - 0.83 8.2 12.9 0.091 11.4 8.4 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 GAK65639.1 - 1.2 9.7 11.5 0.34 11.5 3.6 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal GldM_N PF12081.8 GAK65639.1 - 1.6 8.8 10.2 0.31 11.1 3.8 2.6 2 1 1 3 3 3 0 GldM N-terminal domain Golgin_A5 PF09787.9 GAK65639.1 - 5 6.5 18.4 0.42 10.0 13.7 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Atg14 PF10186.9 GAK65639.1 - 6.2 5.8 17.6 9.9 5.1 17.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 GAK65639.1 - 7.9 6.5 16.7 0.8 9.8 12.3 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rho_Binding PF08912.11 GAK65639.1 - 8.3 7.3 14.8 13 6.7 8.3 2.8 2 0 0 2 2 2 0 Rho Binding Pkinase PF00069.25 GAK65640.1 - 3.5e-60 203.6 0.0 2.5e-59 200.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK65640.1 - 2.6e-27 95.7 0.0 7e-19 68.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK65640.1 - 2.9e-06 26.8 0.0 0.0036 16.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 GAK65640.1 - 0.0024 16.9 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAK65640.1 - 0.0025 17.8 0.1 0.037 14.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAK65640.1 - 0.0064 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAK65640.1 - 0.092 11.8 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 GAK65640.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family zf-4CXXC_R1 PF10497.9 GAK65641.1 - 1e-15 57.8 11.9 2e-15 56.8 11.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 TF_Zn_Ribbon PF08271.12 GAK65641.1 - 0.2 11.2 4.7 0.85 9.2 4.7 2.2 1 0 0 1 1 1 0 TFIIB zinc-binding Sporozoite_P67 PF05642.11 GAK65641.1 - 9.2 4.2 11.8 7.1 4.6 0.7 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MAPEG PF01124.18 GAK65642.1 - 5.3e-28 97.5 2.4 6.1e-28 97.3 2.4 1.0 1 0 0 1 1 1 1 MAPEG family Ferrochelatase PF00762.19 GAK65643.1 - 2.1e-106 355.6 0.0 2.8e-106 355.2 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Synaptobrevin PF00957.21 GAK65643.1 - 1.5e-29 101.6 2.4 2.6e-29 100.9 2.4 1.3 1 0 0 1 1 1 1 Synaptobrevin CbiX PF01903.17 GAK65643.1 - 0.0008 19.7 0.1 2.2 8.6 0.0 2.5 2 0 0 2 2 2 2 CbiX ORF_12_N PF18042.1 GAK65643.1 - 0.16 12.4 0.9 9.3 6.7 0.1 2.5 2 0 0 2 2 2 0 ORF 12 gene product N-terminal UQ_con PF00179.26 GAK65644.1 - 4.1e-27 94.5 0.0 4.9e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GAK65644.1 - 0.0062 16.4 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 GAK65644.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 GAK65644.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 HECT PF00632.25 GAK65645.1 - 1.1e-97 327.3 0.0 1.4e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fructosamin_kin PF03881.14 GAK65646.1 - 4.8e-61 206.5 0.0 5.8e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GAK65646.1 - 3.6e-07 30.4 0.4 5.3e-07 29.8 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phage_GPA PF05840.13 GAK65646.1 - 0.14 11.2 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) FH2 PF02181.23 GAK65647.1 - 0.13 11.4 14.8 0.46 9.6 5.1 2.3 1 1 0 2 2 2 0 Formin Homology 2 Domain KASH_CCD PF14662.6 GAK65647.1 - 0.14 12.0 23.7 0.22 11.3 23.7 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 GAK65647.1 - 0.51 8.8 16.6 0.84 8.1 16.6 1.3 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 GAK65647.1 - 1.5 7.7 24.3 2.4 7.0 24.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 GAK65647.1 - 2 5.8 27.2 2.9 5.3 27.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.6 GAK65647.1 - 7.5 7.0 29.2 2.6 8.5 19.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Golgin_A5 PF09787.9 GAK65647.1 - 8.8 5.7 28.1 3.3 7.1 17.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Bromodomain PF00439.25 GAK65648.1 - 3.9e-31 107.0 0.4 2.9e-15 56.1 0.0 3.4 2 1 0 2 2 2 2 Bromodomain BET PF17035.5 GAK65648.1 - 3.1e-21 75.3 2.5 6.3e-21 74.3 2.5 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Abhydro_lipase PF04083.16 GAK65649.1 - 4.2e-15 55.1 0.0 7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAK65649.1 - 1.9e-07 31.0 0.1 2.9e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK65649.1 - 0.0049 16.2 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Rgp1 PF08737.10 GAK65650.1 - 3.6e-104 349.3 0.0 5.7e-104 348.6 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 GAK65650.1 - 2.7e-06 27.9 0.0 0.0034 17.9 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAK65650.1 - 0.0028 17.7 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 GAK65650.1 - 0.064 12.8 0.1 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 SpoOM protein RFC1 PF08519.12 GAK65651.1 - 5.9e-53 179.2 0.0 2.7e-51 173.8 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 GAK65651.1 - 3.2e-13 49.9 0.0 6.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 GAK65651.1 - 6.4e-09 36.3 0.0 2.1e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAK65651.1 - 6.4e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 GAK65651.1 - 0.0019 17.9 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAK65651.1 - 0.0039 17.2 0.0 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAK65651.1 - 0.0084 16.5 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAK65651.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAK65651.1 - 0.012 16.1 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAK65651.1 - 0.017 15.1 0.0 0.15 11.9 0.0 2.3 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 GAK65651.1 - 0.038 13.7 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAK65651.1 - 0.079 12.9 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 GAK65651.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 GAK65651.1 - 0.094 13.1 0.0 0.41 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA C-terminal domain AAA_7 PF12775.7 GAK65651.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NBD_C PF17042.5 GAK65652.1 - 0.91 10.0 3.8 0.41 11.1 0.5 1.9 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain PUF PF00806.19 GAK65653.1 - 3.9e-64 208.9 8.2 8.4e-09 34.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Cupin_2 PF07883.11 GAK65654.1 - 1.6e-05 24.5 0.0 3.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Cupin domain Lyx_isomer PF07385.12 GAK65654.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 D-lyxose isomerase AraC_binding PF02311.19 GAK65654.1 - 0.16 11.9 0.1 0.42 10.5 0.1 1.7 1 1 0 1 1 1 0 AraC-like ligand binding domain FMO-like PF00743.19 GAK65655.1 - 8.9e-45 153.1 0.0 5.7e-44 150.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAK65655.1 - 1.2e-20 73.9 0.0 3.9e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK65655.1 - 1.8e-19 70.2 0.0 1.4e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK65655.1 - 4e-11 43.1 0.6 2.2e-06 27.5 0.2 4.2 2 2 3 5 5 5 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAK65655.1 - 1.6e-09 37.8 0.0 4.2e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAK65655.1 - 3.8e-09 36.7 0.1 5.3e-05 23.3 0.1 3.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAK65655.1 - 1.2e-08 35.4 0.2 0.00056 20.4 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAK65655.1 - 4.6e-07 29.3 0.0 6.1e-06 25.6 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 GAK65655.1 - 8.9e-07 28.5 0.1 0.0041 16.5 0.0 2.9 2 1 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAK65655.1 - 6.4e-06 25.1 0.1 0.022 13.5 0.2 2.9 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.20 GAK65655.1 - 0.00089 19.3 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 GAK65655.1 - 0.001 18.2 0.0 0.24 10.4 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 GAK65655.1 - 0.0011 18.2 0.5 0.85 8.6 0.0 3.2 3 1 1 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 GAK65655.1 - 0.0017 18.8 0.1 2.9 8.4 0.0 2.7 2 2 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 GAK65655.1 - 0.0022 17.3 0.0 0.0072 15.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 GAK65655.1 - 0.039 13.5 0.2 0.097 12.2 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 GAK65655.1 - 0.041 13.0 0.1 0.2 10.7 0.1 2.0 1 1 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 GAK65655.1 - 0.059 13.6 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 GAK65655.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAK65655.1 - 0.15 11.2 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAK65655.1 - 0.28 10.5 1.4 0.31 10.3 0.3 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FF PF01846.19 GAK65656.1 - 2.1e-27 95.0 9.8 5.8e-07 29.6 0.4 6.7 5 2 0 5 5 5 5 FF domain WW PF00397.26 GAK65656.1 - 2.3e-10 40.4 7.1 3.3e-08 33.5 0.7 2.5 2 0 0 2 2 2 2 WW domain SnoaL_2 PF12680.7 GAK65656.1 - 0.59 10.8 8.4 0.088 13.5 2.2 2.9 2 1 1 3 3 3 0 SnoaL-like domain DUF3752 PF12572.8 GAK65657.1 - 1.6e-15 58.0 48.3 1.1e-10 42.2 16.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3752) Acetate_kinase PF00871.17 GAK65658.1 - 1.5e-71 241.2 0.0 1.9e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Polyketide_cyc2 PF10604.9 GAK65658.1 - 1.6e-10 41.5 0.0 4.5e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport XFP_N PF09364.10 GAK65659.1 - 7.1e-127 423.2 0.0 1.1e-126 422.5 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 GAK65659.1 - 3e-71 239.1 0.0 4.4e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 GAK65659.1 - 4.6e-66 221.9 0.0 8.3e-66 221.0 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 GAK65659.1 - 0.019 14.8 0.2 0.043 13.6 0.2 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.24 GAK65659.1 - 0.062 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain K_oxygenase PF13434.6 GAK65660.1 - 2.8e-13 49.8 1.8 1.1e-09 37.9 0.4 3.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAK65660.1 - 2e-12 47.0 0.2 1.1e-11 44.6 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAK65660.1 - 1e-11 44.7 0.0 8.1e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK65660.1 - 5.3e-11 42.6 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAK65660.1 - 9.6e-10 37.5 0.1 3.6e-09 35.6 0.1 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 GAK65660.1 - 1.2e-05 25.4 0.2 0.03 14.3 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 GAK65660.1 - 1.8e-05 24.5 0.9 0.00021 21.0 0.1 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 GAK65660.1 - 0.00027 20.1 0.4 0.6 9.1 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAK65660.1 - 0.00028 20.4 0.0 0.0043 16.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK65660.1 - 0.00046 19.4 0.0 0.055 12.5 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAK65660.1 - 0.00089 18.4 0.1 0.28 10.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 GAK65660.1 - 0.0011 18.3 0.1 0.0027 17.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 GAK65660.1 - 0.034 14.7 0.0 5.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK65660.1 - 0.082 11.6 0.6 0.19 10.4 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein MucBP_2 PF17965.1 GAK65661.1 - 0.023 15.3 1.0 0.046 14.3 0.1 2.0 2 0 0 2 2 2 0 Mucin binding domain Amidase PF01425.21 GAK65662.1 - 2.8e-84 283.7 0.0 5.3e-74 249.8 0.0 2.1 2 0 0 2 2 2 2 Amidase CCDC106 PF15794.5 GAK65662.1 - 0.019 14.7 0.3 0.032 14.0 0.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PBP1_TM PF14812.6 GAK65666.1 - 7.9 6.9 7.4 3.7 8.0 1.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOC3p PF07540.11 GAK65667.1 - 1.6e-30 105.4 0.0 4.9e-30 103.8 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 GAK65667.1 - 8.6e-11 42.2 0.4 8.6e-11 42.2 0.4 2.6 3 1 0 3 3 3 1 CBF/Mak21 family DnaJ PF00226.31 GAK65668.1 - 1.1e-13 51.1 0.0 2.3e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Nucleos_tra2_C PF07662.13 GAK65668.1 - 0.014 15.2 1.0 0.071 13.0 0.1 2.1 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus 7tm_1 PF00001.21 GAK65669.1 - 1.6e-15 57.1 2.2 2e-15 56.8 2.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 GAK65669.1 - 1.3e-11 44.6 14.8 1.3e-11 44.6 14.8 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 GAK65669.1 - 0.001 19.1 0.1 0.001 19.1 0.1 2.5 3 1 1 4 4 4 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3040 PF11239.8 GAK65670.1 - 3.3 8.0 5.9 3.1 8.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Abhydrolase_1 PF00561.20 GAK65671.1 - 1.6e-36 126.3 0.0 1.2e-35 123.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold SMC_N PF02463.19 GAK65672.1 - 1.2e-19 70.7 0.0 2.6e-19 69.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAK65672.1 - 2.6e-17 64.0 35.7 3.8e-16 60.2 17.7 4.6 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 GAK65672.1 - 1.2e-07 31.9 1.0 0.02 14.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAK65672.1 - 2e-05 24.5 1.5 2e-05 24.5 1.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAK65672.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAK65672.1 - 0.03 14.1 1.1 0.14 11.9 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Homeobox_KN PF05920.11 GAK65672.1 - 0.17 11.8 1.1 8 6.5 0.0 3.5 3 0 0 3 3 3 0 Homeobox KN domain PTCB-BRCT PF12738.7 GAK65672.1 - 0.19 11.7 0.1 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain Seadorna_VP6 PF07407.11 GAK65672.1 - 7.5 5.4 6.1 13 4.6 6.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP6 protein Glyco_hydro_10 PF00331.20 GAK65673.1 - 3.5e-100 335.2 0.0 4.1e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 MaoC_dehydratas PF01575.19 GAK65674.1 - 4e-09 36.1 0.0 8.8e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain p450 PF00067.22 GAK65675.1 - 1.1e-60 205.7 0.0 1.5e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 GAK65676.1 - 7.5e-06 25.7 0.6 2.3e-05 24.2 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK65676.1 - 0.00099 18.9 0.4 0.0088 15.9 0.2 2.7 3 0 0 3 3 3 1 F-box domain PAR1 PF06521.11 GAK65676.1 - 0.18 11.4 0.5 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 PAR1 protein Prefoldin_2 PF01920.20 GAK65676.1 - 0.94 9.5 2.8 0.62 10.0 0.4 1.9 2 0 0 2 2 2 0 Prefoldin subunit LIP PF03583.14 GAK65678.1 - 6.4e-52 176.6 0.1 9.1e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Fungal_trans_2 PF11951.8 GAK65679.1 - 7.8e-10 38.1 0.2 7.8e-10 38.1 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65679.1 - 1.8e-07 31.2 9.8 4.1e-07 30.0 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 GAK65681.1 - 8.8e-43 146.8 0.0 1.2e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 GAK65681.1 - 0.043 13.4 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 GAK65681.1 - 0.07 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase peroxidase PF00141.23 GAK65682.1 - 1.1e-82 277.2 0.0 4.8e-43 147.5 0.0 2.2 2 0 0 2 2 2 2 Peroxidase AA_permease_2 PF13520.6 GAK65683.1 - 1.3e-45 156.0 44.8 1.7e-45 155.7 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAK65683.1 - 1.2e-14 53.8 40.0 1.2e-14 53.8 40.0 2.0 2 0 0 2 2 2 2 Amino acid permease SLATT_fungal PF18142.1 GAK65683.1 - 2 8.5 3.9 9.1 6.3 0.1 3.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Cu_amine_oxid PF01179.20 GAK65684.1 - 1.6e-155 518.0 0.0 2e-155 517.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 GAK65684.1 - 1.2e-05 25.4 0.1 2.7e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 GAK65684.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.8 1 1 0 1 1 1 0 Copper amine oxidase, N3 domain Fungal_trans PF04082.18 GAK65685.1 - 4.4e-16 58.7 0.2 1e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAK65685.1 - 6.1e-08 32.7 14.9 6.7e-05 23.1 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 GAK65685.1 - 1.2e-06 28.5 8.9 1.2e-06 28.5 8.9 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 GAK65685.1 - 1.5e-05 25.4 11.6 0.021 15.6 0.8 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAK65685.1 - 7.8e-05 22.6 7.9 0.03 14.3 3.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAK65685.1 - 0.00092 19.4 3.9 0.32 11.3 2.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAK65685.1 - 0.012 16.0 2.7 1 9.8 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 GAK65685.1 - 0.32 11.5 12.5 0.24 11.9 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-LYAR PF08790.11 GAK65685.1 - 0.36 10.8 2.9 0.75 9.7 0.3 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger CENP-B_dimeris PF09026.10 GAK65685.1 - 0.66 10.4 8.7 0.092 13.1 3.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Aldedh PF00171.22 GAK65687.1 - 5.6e-145 483.4 0.0 6.3e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAK65687.1 - 0.00016 20.9 0.0 0.0047 16.0 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Aldedh PF00171.22 GAK65688.1 - 2.2e-05 23.2 0.2 5.4e-05 21.9 0.2 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LigB PF02900.18 GAK65689.1 - 3.9e-18 65.5 0.0 4.4e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Creatininase PF02633.14 GAK65689.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Creatinine amidohydrolase Peptidase_S15 PF02129.18 GAK65691.1 - 3.3e-37 128.5 0.6 5e-37 127.9 0.6 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAK65691.1 - 1.5e-29 103.6 0.1 2.3e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FAD_binding_3 PF01494.19 GAK65692.1 - 8.4e-13 48.3 0.0 9.2e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAK65692.1 - 4.1e-05 23.7 0.0 9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAK65692.1 - 0.00033 20.0 0.1 0.0077 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK65692.1 - 0.00036 20.2 0.1 0.00088 19.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK65692.1 - 0.05 13.6 0.1 1 9.3 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAK65692.1 - 0.056 12.7 0.2 0.087 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAK65692.1 - 0.1 13.2 0.1 0.54 10.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK65692.1 - 0.11 11.5 0.7 0.17 10.9 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 GAK65692.1 - 0.35 9.7 0.5 9.4 5.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_1 PF00232.18 GAK65693.1 - 2.1e-104 349.5 0.0 3.1e-104 348.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 GAK65693.1 - 0.0078 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAA_hydrolase PF01557.18 GAK65694.1 - 4.6e-45 154.0 0.0 6e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAK65694.1 - 1.8e-23 82.7 0.1 3.5e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal DUF346 PF03984.13 GAK65694.1 - 0.045 13.5 0.3 0.11 12.3 0.3 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) MFS_1 PF07690.16 GAK65695.1 - 1.8e-23 83.1 33.1 4e-12 45.7 8.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 GAK65695.1 - 1.8e-06 27.2 0.1 3.2e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 GAK65695.1 - 0.0015 17.5 4.6 0.056 12.3 1.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Zn_clus PF00172.18 GAK65695.1 - 0.0045 17.1 6.4 0.013 15.6 6.4 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 GAK65696.1 - 7.2e-64 216.2 45.5 9.3e-64 215.8 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAK65696.1 - 6.2e-18 64.6 39.4 8.2e-18 64.2 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 GAK65696.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.6 5 0 0 5 5 5 0 LPXTG cell wall anchor motif DUF1980 PF09323.10 GAK65696.1 - 4.4 7.2 5.7 30 4.5 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1980) TFIIF_beta PF02270.15 GAK65697.1 - 1.5e-30 105.1 0.3 2.5e-30 104.4 0.3 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 GAK65697.1 - 3.2e-22 79.7 0.0 6.3e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus DUF3245 PF11595.8 GAK65697.1 - 4.1 7.9 13.8 2.5 8.6 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Ribonuclease_3 PF00636.26 GAK65698.1 - 8.3e-08 32.8 0.0 2.4e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 GAK65698.1 - 5.2e-07 30.3 0.0 1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 GAK65698.1 - 7.1e-06 26.2 0.0 0.14 12.3 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease-III-like WD40 PF00400.32 GAK65699.1 - 8.3e-40 134.0 10.4 5.4e-09 36.5 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF4078 PF13300.6 GAK65699.1 - 1.3e-10 41.5 4.3 1.3e-10 41.5 4.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) ANAPC4_WD40 PF12894.7 GAK65699.1 - 9.2e-10 38.7 0.9 0.19 12.0 0.1 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK65699.1 - 5e-05 22.4 0.0 3.6 6.4 0.0 3.7 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 GAK65699.1 - 0.00066 18.7 0.1 0.0014 17.6 0.1 1.5 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GAK65699.1 - 0.0012 17.6 5.0 0.58 8.7 0.0 4.2 3 2 1 5 5 5 2 Nucleoporin Nup120/160 VID27 PF08553.10 GAK65699.1 - 0.15 11.0 0.0 0.58 9.1 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Frtz PF11768.8 GAK65699.1 - 0.21 9.9 0.0 0.37 9.1 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz HTH_9 PF08221.11 GAK65700.1 - 5.3e-16 58.5 0.7 1.1e-07 31.8 0.0 5.3 5 0 0 5 5 5 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 GAK65700.1 - 2e-15 57.2 0.1 5.2e-14 52.6 0.2 2.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 GAK65700.1 - 3e-05 23.8 0.2 9.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_24 PF13412.6 GAK65700.1 - 0.52 9.9 3.4 0.99 9.0 0.1 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding TruB_N PF01509.18 GAK65701.1 - 2.6e-38 131.7 0.0 1.7e-37 129.0 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAK65701.1 - 0.0087 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Hydrolase_4 PF12146.8 GAK65702.1 - 3.4e-44 150.9 0.0 9.4e-44 149.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAK65702.1 - 6.8e-10 39.0 0.5 2.4e-07 30.7 0.1 2.7 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK65702.1 - 1.4e-09 38.9 0.0 1.9e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAK65702.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 GAK65702.1 - 0.01 15.4 0.0 0.052 13.0 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 GAK65702.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.7 GAK65702.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 GAK65702.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 GAK65702.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 GAK65702.1 - 0.16 11.4 0.4 6 6.3 0.0 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family DcpS_C PF11969.8 GAK65703.1 - 2.2e-19 70.0 0.0 3.5e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 GAK65703.1 - 7.1e-07 29.9 2.6 5.9e-06 26.9 2.6 2.0 1 1 0 1 1 1 1 HIT domain Methyltransf_11 PF08241.12 GAK65704.1 - 1.2e-20 73.9 0.0 2.1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK65704.1 - 6.1e-20 71.7 0.0 9e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK65704.1 - 2.7e-15 56.8 0.0 5.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK65704.1 - 4.6e-13 49.8 0.0 1.2e-12 48.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK65704.1 - 9e-13 48.3 0.0 3.9e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAK65704.1 - 9.7e-05 21.4 0.0 0.00019 20.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 GAK65704.1 - 0.00014 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 GAK65704.1 - 0.00018 20.9 0.0 0.00063 19.1 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 GAK65704.1 - 0.0045 16.4 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAK65704.1 - 0.0045 16.6 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.11 GAK65704.1 - 0.0047 16.6 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 GAK65704.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mpp10 PF04006.12 GAK65705.1 - 1.5e-109 367.2 118.1 3.4e-95 319.8 35.8 3.3 1 1 1 3 3 3 3 Mpp10 protein BUD22 PF09073.10 GAK65705.1 - 0.00013 21.5 29.4 0.00013 21.5 29.4 5.5 4 1 1 5 5 5 1 BUD22 MarR_2 PF12802.7 GAK65705.1 - 0.026 14.4 0.0 0.088 12.7 0.0 1.9 1 0 0 1 1 1 0 MarR family DAAD PF18752.1 GAK65705.1 - 0.035 14.0 2.0 0.1 12.4 2.0 1.7 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase DENN PF02141.21 GAK65706.1 - 1.3e-19 70.9 0.0 2.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Methyltransf_16 PF10294.9 GAK65706.1 - 1.7e-10 40.9 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase FlxA PF14282.6 GAK65706.1 - 0.0087 16.0 14.6 0.33 11.0 6.2 2.6 2 0 0 2 2 2 2 FlxA-like protein Spc7 PF08317.11 GAK65706.1 - 0.1 11.5 15.4 0.013 14.4 8.7 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Cluap1 PF10234.9 GAK65706.1 - 1.1 8.6 13.9 0.21 11.0 7.5 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 Golgin_A5 PF09787.9 GAK65706.1 - 1.9 7.9 14.8 0.35 10.3 8.6 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 FUSC PF04632.12 GAK65706.1 - 2.7 6.4 12.3 7 5.1 12.3 1.7 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 GAK65706.1 - 3.9 7.7 21.6 0.045 14.0 8.1 3.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Transcrip_act PF04949.13 GAK65706.1 - 5.3 6.9 11.0 2 8.3 7.9 1.8 2 0 0 2 2 2 0 Transcriptional activator OmpH PF03938.14 GAK65706.1 - 5.3 7.4 14.9 3.2 8.1 8.2 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 GAK65706.1 - 5.3 7.1 15.2 3.3 7.8 9.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus XET_C PF06955.12 GAK65707.1 - 0.072 12.9 0.8 0.2 11.5 0.8 1.8 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus ArfGap PF01412.18 GAK65709.1 - 3e-40 136.9 1.7 4.4e-40 136.4 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf baeRF_family8 PF18851.1 GAK65711.1 - 0.084 12.9 0.1 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 SUI1 PF01253.22 GAK65712.1 - 1.4e-13 51.2 0.0 2.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 GAK65712.1 - 0.0013 18.6 0.1 0.002 18.1 0.1 1.2 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Cgr1 PF03879.14 GAK65712.1 - 0.029 14.7 8.8 0.057 13.8 8.8 1.4 1 0 0 1 1 1 0 Cgr1 family DUF1771 PF08590.10 GAK65713.1 - 6.8e-22 77.6 12.3 7.2e-22 77.5 8.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 GAK65713.1 - 5.3e-12 45.9 0.4 1.4e-11 44.6 0.4 1.8 1 0 0 1 1 1 1 Smr domain Peripla_BP_2 PF01497.18 GAK65713.1 - 0.0025 17.4 0.2 0.0048 16.5 0.2 1.6 1 1 0 1 1 1 1 Periplasmic binding protein DUF4407 PF14362.6 GAK65713.1 - 0.41 10.0 4.8 0.6 9.4 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mg_trans_NIPA PF05653.14 GAK65714.1 - 1.3e-26 93.5 7.4 8.7e-14 51.3 2.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA RAMP4 PF06624.12 GAK65714.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Mon1 PF03164.14 GAK65715.1 - 8e-96 321.6 0.0 1.2e-90 304.5 0.0 2.8 2 1 0 2 2 2 2 Trafficking protein Mon1 Thiamine_BP PF01910.17 GAK65716.1 - 4.1e-23 81.1 0.0 5.6e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein MutS_V PF00488.21 GAK65717.1 - 3.5e-79 265.2 0.0 5.9e-79 264.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAK65717.1 - 4.1e-36 125.0 0.7 4.1e-36 125.0 0.7 2.6 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 GAK65717.1 - 3.2e-17 63.1 0.1 1.5e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 GAK65717.1 - 1.2e-15 57.6 3.7 4.8e-15 55.7 0.5 3.0 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 GAK65717.1 - 4.4e-12 46.2 0.0 8.5e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I LTV PF04180.14 GAK65717.1 - 0.13 12.0 3.6 1.8 8.2 0.3 2.2 2 0 0 2 2 2 0 Low temperature viability protein zf-ZPR1 PF03367.13 GAK65717.1 - 0.15 11.9 0.5 1.5 8.7 0.0 2.9 4 1 1 5 5 5 0 ZPR1 zinc-finger domain Ribonuclease_T2 PF00445.18 GAK65718.1 - 1.4e-25 90.6 0.0 2.2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family MutS_V PF00488.21 GAK65719.1 - 1.2e-25 90.6 0.0 1.5e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 MutS domain V Ntox24 PF15529.6 GAK65720.1 - 0.2 12.0 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 24 Peptidase_S8 PF00082.22 GAK65721.1 - 6.9e-40 137.2 6.0 1.2e-39 136.4 6.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 GAK65721.1 - 4.6e-17 62.8 0.4 3.3e-16 60.0 0.1 2.5 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 GAK65721.1 - 8.2e-05 22.6 0.1 0.00044 20.2 0.0 2.3 2 0 0 2 2 2 1 PA domain Trypan_PARP PF05887.11 GAK65721.1 - 0.029 14.3 6.0 0.098 12.6 6.0 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RPT PF13446.6 GAK65721.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Inhibitor_I9 PF05922.16 GAK65721.1 - 0.1 13.3 0.1 0.27 11.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 BCIP PF13862.6 GAK65722.1 - 5.2e-50 170.1 0.0 6.3e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Mpv17_PMP22 PF04117.12 GAK65724.1 - 6.8e-22 77.5 0.2 1.1e-21 76.8 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family EVE PF01878.18 GAK65725.1 - 8.9e-41 139.3 0.0 3.9e-40 137.2 0.0 1.9 1 1 0 1 1 1 1 EVE domain Ribosomal_S11 PF00411.19 GAK65726.1 - 1.8e-44 150.7 1.6 3.2e-44 149.8 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 GAK65726.1 - 0.095 13.0 0.1 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Ribosomal_L38e PF01781.18 GAK65727.1 - 2.2e-33 114.1 1.5 2.7e-33 113.9 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family E6 PF00518.17 GAK65727.1 - 0.013 15.9 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Early Protein (E6) Alph_Pro_TM PF09608.10 GAK65728.1 - 0.0055 16.5 0.0 0.0084 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) C2 PF00168.30 GAK65729.1 - 3.5e-26 91.5 0.0 7.9e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain PITH PF06201.13 GAK65730.1 - 5.4e-35 120.8 0.0 6.7e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain HMG-CoA_red PF00368.18 GAK65731.1 - 4.1e-144 480.1 5.4 6.3e-144 479.5 5.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 GAK65731.1 - 2.7e-16 59.8 1.7 6e-08 32.7 0.1 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAK65731.1 - 3.4e-07 28.8 0.5 0.0016 16.6 0.0 2.3 2 0 0 2 2 2 2 Patched family HPIH PF13323.6 GAK65731.1 - 0.0019 18.1 0.6 0.0046 16.8 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif CLU PF13236.6 GAK65732.1 - 3.5e-75 252.6 0.0 5.7e-75 251.9 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAK65732.1 - 1.6e-45 155.3 0.0 5.1e-45 153.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 GAK65732.1 - 8.8e-18 64.4 6.8 5.5e-08 33.0 1.1 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAK65732.1 - 1.7e-14 53.1 9.4 0.00062 19.6 0.2 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 GAK65732.1 - 3.7e-06 27.2 0.0 1.7e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 GAK65732.1 - 0.0039 17.2 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF727) Borrelia_P83 PF05262.11 GAK65732.1 - 6.9 5.0 16.0 3.8 5.9 1.1 2.3 2 0 0 2 2 2 0 Borrelia P83/100 protein EAP30 PF04157.16 GAK65733.1 - 5.1e-29 101.2 0.0 7.9e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 GAK65733.1 - 9.1e-25 86.7 0.0 1.6e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 GAK65733.1 - 0.0004 19.6 9.6 0.043 13.2 1.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 GAK65733.1 - 0.091 12.8 4.6 0.9 9.6 4.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon Nif11 PF07862.11 GAK65733.1 - 1 9.7 4.8 2.4 8.6 4.8 1.6 1 0 0 1 1 1 0 Nif11 domain Pex19 PF04614.12 GAK65733.1 - 1.2 8.9 3.9 0.66 9.7 1.9 1.6 2 0 0 2 2 2 0 Pex19 protein family Vps36-NZF-N PF16988.5 GAK65733.1 - 6.3 6.3 13.2 0.22 10.9 4.0 3.0 2 2 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Amidohydro_3 PF07969.11 GAK65735.1 - 4.7e-71 240.7 0.1 5.9e-71 240.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAK65735.1 - 3e-17 63.0 0.1 4.9e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family SpoVS PF04232.12 GAK65735.1 - 0.032 14.0 0.4 0.088 12.5 0.4 1.7 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) TctB PF07331.11 GAK65736.1 - 0.056 13.7 4.3 0.13 12.6 2.4 2.0 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4064 PF13273.6 GAK65736.1 - 0.42 10.9 5.1 16 5.8 7.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 GAK65736.1 - 0.59 8.8 2.1 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) O-ag_pol_Wzy PF14296.6 GAK65736.1 - 7.1 5.2 11.0 2.9 6.4 0.0 2.9 3 0 0 3 3 3 0 O-antigen polysaccharide polymerase Wzy PNP_phzG_C PF10590.9 GAK65737.1 - 6e-23 80.6 0.4 1.2e-22 79.6 0.4 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 GAK65737.1 - 1.7e-19 69.8 0.0 2.6e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 GAK65737.1 - 0.0034 18.0 0.0 0.0063 17.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyt-b5 PF00173.28 GAK65738.1 - 2.3e-09 37.2 0.0 2.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_3 PF01494.19 GAK65739.1 - 3.1e-25 89.2 0.1 5.1e-25 88.4 0.1 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAK65739.1 - 4.9e-12 45.7 0.6 1.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK65739.1 - 4.1e-11 43.1 0.7 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAK65739.1 - 1.6e-08 35.0 0.1 0.00014 22.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAK65739.1 - 8.2e-06 24.9 1.1 0.0031 16.4 0.1 2.8 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 GAK65739.1 - 3.3e-05 24.0 0.1 0.0001 22.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAK65739.1 - 0.00021 20.1 0.2 0.17 10.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein CoA_transf_3 PF02515.17 GAK65739.1 - 0.00039 19.7 0.1 0.00064 18.9 0.1 1.3 1 0 0 1 1 1 1 CoA-transferase family III FAD_binding_2 PF00890.24 GAK65739.1 - 0.00074 18.7 1.5 0.024 13.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 GAK65739.1 - 0.0024 17.0 0.4 0.0057 15.8 0.4 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 GAK65739.1 - 0.0052 16.4 0.2 0.01 15.5 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 GAK65739.1 - 0.013 14.8 0.5 0.055 12.8 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GAK65739.1 - 0.018 14.4 0.1 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 GAK65739.1 - 0.039 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 GAK65739.1 - 0.11 12.4 0.3 1.8 8.6 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAK65739.1 - 0.16 11.3 0.6 0.28 10.5 0.6 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase MMR_HSR1_Xtn PF16897.5 GAK65740.1 - 4.7e-39 132.7 1.0 9.3e-39 131.7 0.7 1.7 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GAK65740.1 - 1.6e-21 76.1 0.0 2.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GAK65740.1 - 8.4e-21 74.2 0.0 1.9e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK65740.1 - 5e-09 35.9 0.2 1.5e-08 34.3 0.0 1.9 2 1 1 3 3 3 1 Ferrous iron transport protein B MeaB PF03308.16 GAK65740.1 - 0.088 11.8 3.2 0.13 11.2 0.5 2.3 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAK65740.1 - 0.12 12.4 2.2 1.3 9.0 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Aldo_ket_red PF00248.21 GAK65741.1 - 1e-74 251.4 0.0 1.1e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase2 PF13354.6 GAK65741.1 - 0.08 12.5 0.0 0.4 10.3 0.0 2.1 2 1 0 2 2 2 0 Beta-lactamase enzyme family SCP2 PF02036.17 GAK65742.1 - 1.7e-25 89.4 2.5 1.9e-25 89.2 2.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAK65742.1 - 1.4e-05 25.3 0.9 1.6e-05 25.2 0.9 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Clat_adaptor_s PF01217.20 GAK65744.1 - 8.6e-55 184.6 1.0 1e-54 184.3 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MBOAT PF03062.19 GAK65745.1 - 1.2e-51 176.1 16.4 1.2e-51 176.1 16.4 2.0 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.11 GAK65745.1 - 0.99 9.6 4.9 0.9 9.7 0.1 2.8 3 0 0 3 3 3 0 PufQ cytochrome subunit HemY_N PF07219.13 GAK65746.1 - 0.52 10.5 3.3 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 HemY protein N-terminus Phage_holin_3_6 PF07332.11 GAK65746.1 - 0.61 10.1 10.2 0.095 12.7 2.3 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Bot1p PF12298.8 GAK65748.1 - 9.1e-34 117.1 0.1 1.6e-33 116.3 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 GAK65748.1 - 0.00055 20.1 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 EMC3_TMCO1 PF01956.16 GAK65749.1 - 1.1e-58 197.8 0.2 1.4e-58 197.4 0.2 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like NPR3 PF03666.13 GAK65750.1 - 6.7e-120 401.0 15.0 1.7e-118 396.4 0.0 3.5 3 1 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S24 PF00717.23 GAK65750.1 - 0.0021 18.0 0.0 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 Peptidase S24-like NPR2 PF06218.11 GAK65750.1 - 0.013 14.3 0.0 1.9 7.2 0.0 3.3 4 0 0 4 4 4 0 Nitrogen permease regulator 2 Borrelia_P83 PF05262.11 GAK65750.1 - 0.35 9.3 8.8 0.71 8.3 8.8 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein PEMT PF04191.13 GAK65751.1 - 2.2e-54 182.3 9.5 6.8e-32 110.0 1.6 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF4199 PF13858.6 GAK65751.1 - 1.4 9.3 5.5 1.6 9.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Mg_trans_NIPA PF05653.14 GAK65752.1 - 1.8e-106 355.6 16.2 2.4e-106 355.2 16.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA RRM_1 PF00076.22 GAK65752.1 - 5.5e-23 80.6 0.0 2.5e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EamA PF00892.20 GAK65752.1 - 0.00079 19.6 3.9 0.00079 19.6 3.9 4.0 3 1 0 3 3 3 1 EamA-like transporter family MAGE PF01454.19 GAK65753.1 - 2.6e-46 158.0 0.0 4.2e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 MAGE family LRR_8 PF13855.6 GAK65754.1 - 7.3e-19 67.3 21.6 6.2e-11 41.9 7.6 5.3 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 GAK65754.1 - 1.6e-17 63.3 14.5 2.3e-06 27.8 4.0 5.4 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) Torus PF16131.5 GAK65754.1 - 3.7e-07 30.8 4.3 0.0037 18.0 0.4 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 GAK65754.1 - 1e-06 28.4 8.7 0.00089 19.0 1.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 GAK65754.1 - 7.7e-06 25.7 6.2 0.00052 19.9 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_1 PF00560.33 GAK65754.1 - 1.3e-05 25.1 16.2 9.6 7.2 0.1 7.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 GAK65754.1 - 4.2e-05 23.3 19.6 4.3 7.7 0.1 7.3 7 0 0 7 7 7 3 Leucine Rich repeat zf-CCCH_3 PF15663.5 GAK65754.1 - 0.00069 19.8 0.2 0.0015 18.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 GAK65754.1 - 0.0015 18.5 15.7 0.0061 16.6 3.4 2.4 2 0 0 2 2 2 2 Zinc finger domain LRR_3 PF07725.12 GAK65754.1 - 0.019 14.8 0.5 0.019 14.8 0.5 2.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.6 GAK65754.1 - 0.098 12.1 0.2 0.83 9.1 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeat adh_short PF00106.25 GAK65755.1 - 7.7e-24 84.2 5.7 1.4e-20 73.5 0.7 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK65755.1 - 6e-17 62.0 7.1 2.2e-13 50.3 1.5 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK65755.1 - 1.2e-08 35.1 0.1 2.2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF2018 PF09442.10 GAK65755.1 - 0.0013 19.7 0.1 0.0027 18.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2018) Epimerase PF01370.21 GAK65755.1 - 0.099 12.1 0.1 0.34 10.3 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MT-A70 PF05063.14 GAK65756.1 - 2.8e-50 170.6 0.0 1.3e-33 116.4 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Torus PF16131.5 GAK65756.1 - 1.7 9.4 6.5 0.79 10.4 0.8 2.5 1 1 1 2 2 2 0 Torus domain WD40 PF00400.32 GAK65759.1 - 8.1e-28 96.1 26.9 2.4e-05 25.0 0.6 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 GAK65759.1 - 1.1e-09 38.0 0.2 3.3e-09 36.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK65759.1 - 0.0011 18.7 0.1 0.0043 16.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 GAK65759.1 - 0.0022 18.2 0.5 28 5.1 0.0 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HD PF01966.22 GAK65759.1 - 0.12 12.6 0.1 2 8.7 0.0 2.5 2 0 0 2 2 2 0 HD domain ADH_zinc_N PF00107.26 GAK65760.1 - 1.9e-11 44.1 0.1 3e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.16 GAK65760.1 - 0.00045 19.9 0.1 0.00069 19.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_2 PF08028.11 GAK65761.1 - 9.8e-12 45.3 2.3 1.7e-11 44.5 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAK65761.1 - 2.3e-07 31.5 0.4 1.2e-06 29.2 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAK65761.1 - 0.00027 21.1 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAK65761.1 - 0.053 13.7 1.1 0.23 11.7 1.1 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-C2H2_2 PF12756.7 GAK65762.1 - 0.065 13.6 0.1 0.065 13.6 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 GAK65762.1 - 0.42 11.1 0.1 0.42 11.1 0.1 2.1 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D PI-PLC-X PF00388.19 GAK65763.1 - 1.3e-56 190.3 0.0 2.2e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAK65763.1 - 1.2e-39 135.2 0.0 2.6e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.6 GAK65763.1 - 1.2e-06 28.9 2.2 3.3e-06 27.5 0.5 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAK65763.1 - 3.4e-05 23.1 0.1 0.15 11.6 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAK65763.1 - 0.00033 20.3 0.2 0.82 9.8 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain C2 PF00168.30 GAK65763.1 - 0.0042 17.3 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 1 C2 domain EF-hand_10 PF14788.6 GAK65763.1 - 0.03 14.2 0.1 0.074 12.9 0.1 1.7 1 0 0 1 1 1 0 EF hand CreD PF06123.12 GAK65763.1 - 0.064 12.0 0.4 0.11 11.3 0.4 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD EF-hand_8 PF13833.6 GAK65763.1 - 0.18 11.6 0.3 34 4.4 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair DPBB_1 PF03330.18 GAK65764.1 - 1.1e-05 25.6 0.0 2.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase C6_DPF PF10170.9 GAK65764.1 - 0.1 13.0 1.0 0.15 12.4 1.0 1.2 1 0 0 1 1 1 0 Cysteine-rich domain ILVD_EDD PF00920.21 GAK65765.1 - 8.1e-207 687.9 0.7 9.2e-207 687.7 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family Methyltransf_16 PF10294.9 GAK65766.1 - 6.9e-07 29.2 0.0 0.0023 17.7 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 GAK65766.1 - 0.00031 21.4 0.0 0.15 12.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GAK65766.1 - 0.00084 19.2 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GAK65766.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain YdjC PF04794.12 GAK65766.1 - 0.05 13.6 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 YdjC-like protein GST_C_2 PF13410.6 GAK65767.1 - 1.6e-15 56.9 0.1 5.7e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAK65767.1 - 4.1e-06 27.1 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK65767.1 - 4.2e-05 23.8 0.0 7.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAK65767.1 - 0.09 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Torus PF16131.5 GAK65768.1 - 9.1e-30 103.6 5.6 4.5e-29 101.3 5.6 2.2 1 1 0 1 1 1 1 Torus domain RRM_1 PF00076.22 GAK65768.1 - 1.1e-07 31.5 0.2 5.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAK65768.1 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 GAK65768.1 - 0.016 15.1 5.3 0.031 14.2 5.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK65768.1 - 0.58 10.3 5.3 1.1 9.4 5.3 1.5 1 0 0 1 1 1 0 Zinc finger domain RRM_3 PF08777.11 GAK65768.1 - 1.4 9.0 3.8 17 5.5 0.0 2.6 1 1 0 2 2 2 0 RNA binding motif DUF572 PF04502.13 GAK65768.1 - 5.6 6.5 9.2 1.1 8.8 5.9 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) LRR_6 PF13516.6 GAK65769.1 - 2.1e-12 46.0 28.3 0.0009 19.1 0.0 10.0 10 0 0 10 10 10 4 Leucine Rich repeat GAT PF03127.14 GAK65769.1 - 2e-05 24.8 0.0 7.2e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 GAT domain LRR_4 PF12799.7 GAK65769.1 - 0.00076 19.8 24.3 0.056 13.9 0.4 7.2 5 1 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAK65769.1 - 0.098 12.4 22.3 5.9 6.7 0.0 6.9 5 1 3 8 8 8 0 Leucine rich repeat LRR_1 PF00560.33 GAK65769.1 - 0.14 12.8 18.4 54 4.9 0.0 8.4 10 1 0 10 10 10 0 Leucine Rich Repeat Pal1 PF08316.11 GAK65770.1 - 1.4e-12 48.6 0.3 1.4e-12 48.6 0.3 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein HNH_3 PF13392.6 GAK65772.1 - 1.6e-09 37.3 0.6 7e-09 35.3 0.2 2.0 2 0 0 2 2 2 1 HNH endonuclease PyrI PF01948.18 GAK65772.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain HNH_3 PF13392.6 GAK65773.1 - 6.5e-17 61.0 6.6 5.8e-10 38.8 0.4 2.4 2 0 0 2 2 2 2 HNH endonuclease PyrI PF01948.18 GAK65773.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain ATG22 PF11700.8 GAK65774.1 - 2.5e-131 438.6 10.6 3.1e-131 438.3 10.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAK65774.1 - 6.8e-11 41.7 29.6 3.8e-06 26.1 7.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily LAMTOR PF15454.6 GAK65775.1 - 0.0027 18.3 1.1 0.0048 17.5 0.3 1.9 2 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator CTD PF12815.7 GAK65775.1 - 1.2 9.7 5.9 15 6.3 5.8 2.7 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 zf-RING_2 PF13639.6 GAK65776.1 - 1.6e-10 41.1 6.7 2.8e-10 40.4 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAK65776.1 - 3.4e-07 30.0 4.7 5.9e-07 29.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAK65776.1 - 5.6e-07 29.7 5.5 8.1e-07 29.2 4.7 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAK65776.1 - 1.2e-06 28.5 2.2 1.2e-06 28.5 2.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAK65776.1 - 4.5e-06 26.5 4.3 7.8e-06 25.8 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAK65776.1 - 8e-06 25.6 8.5 0.00012 21.8 8.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAK65776.1 - 4e-05 23.2 1.7 8.6e-05 22.1 1.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAK65776.1 - 6.7e-05 22.7 0.6 6.7e-05 22.7 0.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAK65776.1 - 0.00098 19.1 2.5 0.0019 18.2 2.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 GAK65776.1 - 0.0042 16.8 2.9 0.023 14.5 2.9 2.2 1 1 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 GAK65776.1 - 0.027 14.3 3.7 0.054 13.3 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 GAK65776.1 - 0.028 14.7 0.9 0.07 13.5 0.9 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 GAK65776.1 - 0.047 13.6 8.6 0.53 10.2 8.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAK65776.1 - 0.092 12.9 4.8 0.63 10.3 4.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 GAK65776.1 - 0.17 12.1 5.1 0.51 10.5 5.1 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 GAK65776.1 - 0.35 10.7 5.8 1.4 8.8 5.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAK65776.1 - 0.37 11.0 6.7 0.2 11.8 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1729 PF08354.10 GAK65777.1 - 2e-161 536.8 0.0 3.4e-161 536.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 GAK65777.1 - 2.2e-77 259.3 0.3 4e-77 258.4 0.3 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 GAK65777.1 - 2.1e-68 229.7 0.0 4.2e-68 228.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 GAK65777.1 - 1.9e-61 208.3 0.0 5.2e-61 206.9 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 GAK65777.1 - 2.2e-45 154.1 0.0 4.8e-45 153.0 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 GAK65777.1 - 2.8e-28 99.3 0.7 5e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 GAK65777.1 - 9.2e-27 93.1 0.1 8e-26 90.0 0.0 2.4 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.26 GAK65777.1 - 1.1e-26 93.9 0.4 2.8e-26 92.6 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAK65777.1 - 1.1e-17 64.1 2.5 2.3e-17 63.1 0.5 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 GAK65777.1 - 4.5e-12 46.1 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily FAS_N PF17828.1 GAK65777.1 - 3.6e-11 43.2 0.2 8.1e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 GAK65777.1 - 4.2e-10 39.9 0.0 1.6e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 GAK65777.1 - 0.00014 21.3 0.0 0.00043 19.8 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 GAK65777.1 - 0.0076 15.6 0.7 0.024 14.0 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF3597 PF12200.8 GAK65777.1 - 0.33 11.5 4.1 1.3 9.6 4.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) UQ_con PF00179.26 GAK65778.1 - 2.6e-37 127.6 0.1 3.1e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Astro_capsid_p2 PF16580.5 GAK65778.1 - 0.012 15.1 0.3 0.017 14.6 0.3 1.2 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike DUF4611 PF15387.6 GAK65778.1 - 0.067 13.4 1.0 0.11 12.7 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) LSM PF01423.22 GAK65779.1 - 8.2e-17 60.7 0.8 1.2e-16 60.2 0.8 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAK65779.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Hfq protein NDK PF00334.19 GAK65780.1 - 1.6e-50 170.6 0.0 2.1e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Sin_N PF04801.13 GAK65781.1 - 9.8e-33 114.0 0.0 1.6e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region Serglycin PF04360.12 GAK65781.1 - 0.25 11.3 2.1 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 Serglycin Pex24p PF06398.11 GAK65782.1 - 2.9e-27 95.6 5.2 4.6e-27 94.9 0.2 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Gtr1_RagA PF04670.12 GAK65783.1 - 4.5e-25 88.4 0.1 7.6e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 GAK65783.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAK65783.1 - 0.004 17.2 0.0 0.0096 16.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 GAK65783.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 GAK65783.1 - 0.19 11.1 0.1 2.3 7.7 0.1 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family RNase_P_pop3 PF08228.11 GAK65784.1 - 4.3e-05 23.6 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF1640 PF07798.11 GAK65784.1 - 0.073 13.1 1.6 0.18 11.9 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YbjM PF11045.8 GAK65784.1 - 0.17 12.1 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae Di19_C PF14571.6 GAK65784.1 - 6.1 7.4 15.3 0.11 13.0 6.1 2.7 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Oxysterol_BP PF01237.18 GAK65785.1 - 3.2e-48 164.5 0.0 8.3e-25 87.4 0.0 3.2 2 1 1 3 3 3 3 Oxysterol-binding protein Ada3 PF10198.9 GAK65786.1 - 2e-31 108.8 0.3 2e-31 108.8 0.3 2.3 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 HEAT PF02985.22 GAK65787.1 - 6.6e-38 125.5 18.4 0.0038 17.4 0.0 13.7 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 GAK65787.1 - 1.5e-34 118.2 9.2 7.7e-12 45.4 0.0 7.3 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 GAK65787.1 - 1.4e-11 44.6 8.4 0.23 12.0 0.1 8.6 7 1 2 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAK65787.1 - 1.4e-11 44.8 1.5 0.0087 16.6 0.0 7.0 4 2 4 8 8 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAK65787.1 - 4.7e-09 36.5 9.1 0.0074 16.4 0.0 5.5 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAK65787.1 - 7.1e-07 28.2 7.2 0.074 11.6 0.1 4.7 3 1 1 5 5 5 3 Adaptin N terminal region RTP1_C1 PF10363.9 GAK65787.1 - 0.00012 22.2 2.6 5 7.3 0.0 4.3 4 2 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 GAK65787.1 - 0.0086 15.7 1.2 0.86 9.1 0.1 4.1 2 2 2 4 4 4 1 CLASP N terminal V-ATPase_H_N PF03224.14 GAK65787.1 - 0.015 14.6 0.4 0.26 10.5 0.4 2.8 1 1 0 1 1 1 0 V-ATPase subunit H Med24_N PF11277.8 GAK65787.1 - 0.015 13.4 0.1 0.023 12.8 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal API5 PF05918.11 GAK65787.1 - 0.026 13.3 0.5 0.2 10.4 0.1 2.7 2 1 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Proteasom_PSMB PF10508.9 GAK65787.1 - 0.035 12.6 1.9 8.4 4.8 0.1 3.6 3 1 0 4 4 4 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.16 GAK65787.1 - 0.084 13.6 0.2 22 6.1 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat TTRAP PF14203.6 GAK65787.1 - 0.12 12.3 0.3 93 3.1 0.0 4.1 4 0 0 4 4 4 0 Putative tranposon-transfer assisting protein ACBP PF00887.19 GAK65788.1 - 8.2e-31 106.1 0.4 9.8e-31 105.8 0.4 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein DUF3961 PF13106.6 GAK65788.1 - 0.024 14.3 0.5 0.068 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) SWIB PF02201.18 GAK65790.1 - 1.8e-22 79.0 0.0 3.1e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Memo PF01875.17 GAK65791.1 - 1.7e-75 253.7 0.0 3.4e-75 252.7 0.0 1.5 1 1 0 1 1 1 1 Memo-like protein Ribosomal_S3_C PF00189.20 GAK65792.1 - 6.8e-24 84.2 0.2 2.2e-23 82.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAK65792.1 - 1e-12 47.7 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GAK65792.1 - 0.078 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 HABP4_PAI-RBP1 PF04774.15 GAK65793.1 - 1.2e-11 45.5 8.3 1.2e-11 45.5 8.3 3.1 2 2 2 4 4 4 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 GAK65793.1 - 0.012 16.4 19.4 0.012 16.4 19.4 5.3 2 2 0 2 2 2 0 Stm1 Arrestin_N PF00339.29 GAK65794.1 - 1.8e-07 31.3 0.0 4.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAK65794.1 - 0.00046 20.7 0.0 0.15 12.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 GAK65794.1 - 0.008 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 SpoOM protein Borrelia_P83 PF05262.11 GAK65794.1 - 0.46 8.9 17.3 0.17 10.4 14.8 1.5 2 0 0 2 2 2 0 Borrelia P83/100 protein SSF PF00474.17 GAK65796.1 - 2.9e-12 46.2 17.5 7.3e-12 44.8 17.5 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family RPAP2_Rtr1 PF04181.13 GAK65797.1 - 1.1e-17 64.1 0.0 2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family NUDIX PF00293.28 GAK65798.1 - 1.4e-10 41.3 0.0 3.7e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain TIMELESS PF04821.14 GAK65799.1 - 9.6e-73 244.8 0.0 2.5e-72 243.4 0.0 1.8 1 0 0 1 1 1 1 Timeless protein Fe-ADH PF00465.19 GAK65799.1 - 0.0049 15.7 0.3 0.0094 14.8 0.3 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase HLH PF00010.26 GAK65801.1 - 6.8e-18 64.4 0.0 2.2e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cwf_Cwc_15 PF04889.12 GAK65801.1 - 7.1 6.3 25.7 2.7 7.6 17.9 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DCP1 PF06058.13 GAK65802.1 - 1.7e-32 111.8 0.0 2.6e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 GAK65802.1 - 1.1e-05 24.6 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus SR-25 PF10500.9 GAK65802.1 - 0.0027 17.4 9.1 0.0027 17.4 9.1 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein HNOBA PF07701.14 GAK65802.1 - 0.0028 17.1 0.4 0.0035 16.8 0.4 1.2 1 0 0 1 1 1 1 Heme NO binding associated VPS38 PF17649.1 GAK65802.1 - 0.12 11.3 0.8 0.16 10.8 0.8 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DUF4746 PF15928.5 GAK65802.1 - 0.17 11.3 8.9 0.27 10.6 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Coilin_N PF15862.5 GAK65802.1 - 0.34 10.7 9.5 0.61 9.9 9.5 1.4 1 0 0 1 1 1 0 Coilin N-terminus NARP1 PF12569.8 GAK65802.1 - 0.39 9.6 15.4 0.54 9.1 15.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 GAK65802.1 - 0.39 8.9 5.9 0.47 8.7 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 GAK65802.1 - 0.42 10.8 5.9 0.67 10.2 5.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2151 PF10221.9 GAK65802.1 - 1.2 7.7 6.7 1.5 7.3 6.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SOBP PF15279.6 GAK65802.1 - 1.8 9.1 14.7 2.4 8.7 14.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Vfa1 PF08432.10 GAK65802.1 - 2.8 8.2 15.1 6.2 7.1 15.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3987 PF13148.6 GAK65802.1 - 3.6 6.5 10.4 5.9 5.8 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Med24_N PF11277.8 GAK65802.1 - 3.8 5.4 4.8 5.3 5.0 4.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF2681 PF10883.8 GAK65802.1 - 3.9 8.0 11.0 8.8 6.8 11.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Paramyxo_ncap PF00973.19 GAK65802.1 - 6.2 5.6 8.2 9.2 5.0 8.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Yippee-Mis18 PF03226.14 GAK65803.1 - 2e-22 79.4 0.1 2.9e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FXMRP1_C_core PF12235.8 GAK65803.1 - 0.03 14.9 2.0 0.077 13.6 2.0 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal FoP_duplication PF13865.6 GAK65803.1 - 4.7 7.8 7.7 9 6.9 7.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Redoxin PF08534.10 GAK65804.1 - 8.4e-33 113.2 0.1 1.2e-32 112.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAK65804.1 - 1.7e-06 27.9 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF4687 PF15747.5 GAK65804.1 - 0.036 14.5 0.4 0.083 13.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) Aa_trans PF01490.18 GAK65805.1 - 7.1e-81 272.0 33.5 8.5e-81 271.7 33.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PTPRCAP PF15713.5 GAK65805.1 - 0.11 12.8 5.4 0.025 14.8 2.2 1.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GAK65805.1 - 0.26 9.5 2.6 0.43 8.8 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein YpmT PF17431.2 GAK65805.1 - 0.94 9.6 3.2 1.9 8.6 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized YmpT-like UCR_TM PF02921.14 GAK65805.1 - 1.8 9.1 8.3 0.32 11.5 0.5 3.5 4 0 0 4 4 4 0 Ubiquinol cytochrome reductase transmembrane region DNA_pol_phi PF04931.13 GAK65805.1 - 3 5.8 4.6 4.6 5.2 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi PHO4 PF01384.20 GAK65805.1 - 6.6 5.7 21.8 1.3e+02 1.5 21.5 2.7 1 1 0 1 1 1 0 Phosphate transporter family NOA36 PF06524.12 GAK65805.1 - 7.8 5.7 5.8 13 5.0 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3395 PF11875.8 GAK65806.1 - 3.6e-43 147.2 0.0 7.5e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 GAK65806.1 - 2.2e-21 75.8 0.9 3.8e-21 75.0 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain Med5 PF08689.10 GAK65807.1 - 1.4e-23 82.8 0.0 5.6e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit Med5 Amidohydro_1 PF01979.20 GAK65808.1 - 9.1e-58 196.2 0.0 1.8e-27 96.6 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.11 GAK65808.1 - 0.00011 21.8 0.0 2 7.8 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family PAPS_reduct PF01507.19 GAK65809.1 - 3.2e-37 128.2 0.0 4.8e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family NTP_transferase PF00483.23 GAK65812.1 - 1.4e-43 149.3 0.0 2.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 GAK65812.1 - 2.8e-05 24.0 0.1 4.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Atg14 PF10186.9 GAK65813.1 - 2.7e-10 39.8 1.6 5.2e-10 38.9 1.6 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L36 PF00444.18 GAK65815.1 - 7e-22 77.3 8.0 7e-22 77.3 8.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L36 VBS PF08913.10 GAK65815.1 - 0.023 15.1 2.0 0.027 14.9 2.0 1.1 1 0 0 1 1 1 0 Vinculin Binding Site FeS_assembly_P PF01883.19 GAK65815.1 - 0.082 13.1 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein Urb2 PF10441.9 GAK65816.1 - 6.7e-46 156.8 5.9 1.2e-43 149.4 0.1 3.2 3 0 0 3 3 3 2 Urb2/Npa2 family DUF2877 PF11392.8 GAK65816.1 - 0.034 14.9 3.6 3.2 8.5 0.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Ctf8 PF09696.10 GAK65817.1 - 1.7e-14 54.4 3.8 2.4e-11 44.2 3.8 3.0 1 1 0 1 1 1 1 Ctf8 VIR_N PF15912.5 GAK65817.1 - 0.022 14.3 2.9 0.032 13.8 2.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal ASH PF15780.5 GAK65819.1 - 2.4e-17 62.9 0.0 0.027 14.7 0.1 7.2 8 0 0 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 GAK65819.1 - 6.1e-07 29.6 0.1 0.3 11.3 0.1 4.9 5 0 0 5 5 5 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 GAK65819.1 - 0.0002 21.6 0.6 18 5.6 0.0 6.4 6 1 2 8 8 8 2 Transmembrane protein 131-like DUF1573 PF07610.11 GAK65819.1 - 0.036 14.1 0.1 80 3.4 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1573) PUF PF00806.19 GAK65821.1 - 5e-09 35.4 0.0 0.0019 17.8 0.0 5.8 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat Frag1 PF10277.9 GAK65822.1 - 2.5e-33 115.5 5.1 2.5e-33 115.5 5.1 2.2 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family SLD5_C PF16922.5 GAK65824.1 - 1.7e-13 50.6 0.0 3.1e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus TRAM_LAG1_CLN8 PF03798.16 GAK65825.1 - 6.8e-32 110.8 28.2 6.8e-32 110.8 28.2 2.3 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 GAK65825.1 - 2.8e-24 84.5 0.1 2.8e-24 84.5 0.1 2.5 3 0 0 3 3 3 1 TRAM1-like protein Succ_CoA_lig PF13607.6 GAK65825.1 - 0.037 13.8 1.5 0.079 12.8 1.5 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Utp14 PF04615.13 GAK65826.1 - 0.008 14.8 1.0 0.01 14.5 1.0 1.1 1 0 0 1 1 1 1 Utp14 protein Amnionless PF14828.6 GAK65826.1 - 0.0091 14.9 0.4 0.063 12.1 0.0 2.0 1 1 1 2 2 2 1 Amnionless DUF1279 PF06916.13 GAK65827.1 - 9.5e-22 77.4 0.0 1.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L13e PF01294.18 GAK65829.1 - 2.3e-74 249.1 7.6 3.1e-74 248.7 7.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e NIR_SIR PF01077.22 GAK65830.1 - 2.2e-44 150.8 0.0 8e-41 139.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GAK65830.1 - 2.1e-29 101.2 0.0 1.1e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 GAK65830.1 - 1.3e-26 93.5 0.0 2.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 GAK65830.1 - 4.2e-09 36.5 0.0 9.7e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg His_Phos_1 PF00300.22 GAK65832.1 - 5.1e-22 78.5 0.0 7.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dus PF01207.17 GAK65833.1 - 1.1e-40 139.6 0.1 1.9e-40 138.9 0.1 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyridox_oxase_2 PF12766.7 GAK65833.1 - 2.2e-23 82.8 0.0 4.9e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Vps39_1 PF10366.9 GAK65834.1 - 8.2e-31 106.5 0.0 2.8e-30 104.8 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 GAK65834.1 - 1.5e-24 86.6 0.1 3.3e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 GAK65834.1 - 2.1e-13 50.5 0.0 0.00035 20.3 0.0 3.3 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.20 GAK65834.1 - 3.5e-08 33.4 0.1 0.00055 19.8 0.0 3.7 3 1 0 3 3 3 2 Region in Clathrin and VPS TPR_19 PF14559.6 GAK65834.1 - 0.035 14.6 3.7 0.071 13.6 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat PH_12 PF16457.5 GAK65834.1 - 0.13 12.8 0.1 0.33 11.5 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain RHS PF03527.14 GAK65834.1 - 0.14 12.0 0.2 0.33 10.8 0.2 1.6 1 0 0 1 1 1 0 RHS protein DUF1828 PF08861.10 GAK65834.1 - 0.16 12.3 0.0 20 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF1828 TPR_12 PF13424.6 GAK65834.1 - 0.43 10.9 7.9 0.47 10.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 GAK65836.1 - 3.5e-41 141.2 0.0 3e-16 59.1 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 GAK65836.1 - 1.8e-10 41.0 0.0 2e-08 34.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain LAL_C2 PF18603.1 GAK65836.1 - 0.14 12.3 0.5 4.4 7.5 0.1 3.1 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 DGCR6 PF07324.11 GAK65837.1 - 0.0064 16.1 0.8 0.012 15.3 0.8 1.5 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF444 PF04285.12 GAK65837.1 - 0.091 11.8 2.2 0.13 11.4 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Nsp1_C PF05064.13 GAK65837.1 - 0.56 10.0 5.3 8.6 6.2 0.1 2.6 2 1 1 3 3 3 0 Nsp1-like C-terminal region Strabismus PF06638.11 GAK65837.1 - 1 7.9 4.7 1.6 7.3 4.7 1.2 1 0 0 1 1 1 0 Strabismus protein DLIC PF05783.11 GAK65837.1 - 1.5 7.6 3.4 0.3 9.9 0.3 1.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) THUMP PF02926.17 GAK65838.1 - 4.4e-08 33.3 0.0 1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 THUMP domain HEAT_EZ PF13513.6 GAK65839.1 - 4.9e-05 23.7 23.1 0.089 13.3 0.0 7.6 5 1 1 6 6 6 3 HEAT-like repeat Adaptin_N PF01602.20 GAK65839.1 - 7.6e-05 21.5 2.4 0.017 13.7 0.0 4.0 4 1 1 5 5 5 2 Adaptin N terminal region Arm PF00514.23 GAK65839.1 - 9.7e-05 22.3 0.3 0.006 16.6 0.1 3.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 GAK65839.1 - 0.00067 20.2 0.0 0.35 11.5 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 GAK65839.1 - 0.0056 15.9 0.1 14 4.8 0.0 3.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 GAK65839.1 - 0.0065 16.5 1.0 6.6 6.8 0.0 5.5 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAK65839.1 - 0.086 13.2 27.0 4.3 7.8 1.3 8.9 8 2 2 10 10 10 0 HEAT repeats Patatin PF01734.22 GAK65839.1 - 0.11 12.7 1.5 0.92 9.6 0.4 2.6 2 0 0 2 2 2 0 Patatin-like phospholipase HEAT PF02985.22 GAK65839.1 - 0.31 11.4 0.0 0.31 11.4 0.0 9.3 11 0 0 11 11 11 0 HEAT repeat UCH PF00443.29 GAK65840.1 - 2.4e-38 132.1 0.0 8.4e-38 130.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 GAK65840.1 - 6.7e-20 70.8 8.9 7.5e-17 61.0 3.1 3.7 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 GAK65840.1 - 2.5e-05 24.0 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pox_A_type_inc PF04508.12 GAK65840.1 - 0.25 11.3 0.8 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Csm1_N PF18504.1 GAK65840.1 - 0.32 11.3 1.6 5.4 7.4 0.1 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain MCM_bind PF09739.9 GAK65840.1 - 0.37 9.2 1.3 0.42 9.0 0.3 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor CENP-F_leu_zip PF10473.9 GAK65840.1 - 0.39 10.7 5.7 0.65 10.0 0.1 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.6 GAK65840.1 - 0.56 10.7 6.0 5 7.6 0.1 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) WXG100 PF06013.12 GAK65840.1 - 2 8.7 4.2 36 4.7 0.2 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Vps8 PF12816.7 GAK65842.1 - 1.5e-70 236.8 0.0 3.4e-70 235.6 0.0 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 ANAPC4_WD40 PF12894.7 GAK65842.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAK65842.1 - 0.19 12.6 0.5 0.61 11.1 0.5 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat PQQ_3 PF13570.6 GAK65842.1 - 0.39 11.3 1.8 1 9.9 0.2 2.6 2 0 0 2 2 2 0 PQQ-like domain dUTPase PF00692.19 GAK65843.1 - 2.8e-44 149.9 0.0 3.8e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 dUTPase Dynamin_N PF00350.23 GAK65844.1 - 2e-43 148.4 0.0 8.3e-43 146.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 GAK65844.1 - 6.7e-06 25.5 0.1 0.00051 19.3 0.1 2.9 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 GAK65844.1 - 1.8e-05 24.8 0.0 0.00032 20.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 GAK65844.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 GAK65844.1 - 0.073 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.6 GAK65844.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cation_efflux PF01545.21 GAK65845.1 - 2.4e-49 167.8 15.6 5.6e-49 166.6 15.6 1.6 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAK65845.1 - 0.027 14.6 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter RPN1_RPN2_N PF17781.1 GAK65846.1 - 1.3e-122 409.1 0.6 1.9e-122 408.6 0.6 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 GAK65846.1 - 3.4e-27 94.3 0.0 6.2e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 GAK65846.1 - 5.7e-18 64.4 17.1 0.0038 17.6 0.1 8.1 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAK65846.1 - 0.00093 19.5 2.3 0.68 10.4 0.0 4.4 3 1 1 4 4 4 2 HEAT repeats Bac_surface_Ag PF01103.23 GAK65849.1 - 2e-35 122.9 0.2 1.4e-34 120.1 0.2 2.0 1 1 0 1 1 1 1 Surface antigen RNA_pol_Rbc25 PF08292.12 GAK65850.1 - 1.1e-42 145.3 0.0 1.4e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 GAK65850.1 - 2.5e-19 69.4 0.0 4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 GAK65850.1 - 0.026 14.8 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain RhoGAP PF00620.27 GAK65851.1 - 2.6e-37 128.0 0.0 3.9e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 GAK65851.1 - 0.0024 17.1 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SOG2 PF10428.9 GAK65852.1 - 4.1 6.5 9.1 4.3 6.4 9.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1741 PF08427.10 GAK65854.1 - 3.8e-23 82.4 0.0 6.9e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DDE_Tnp_1_assoc PF13808.6 GAK65854.1 - 0.073 13.1 1.0 1 9.4 0.0 3.1 3 0 0 3 3 3 0 DDE_Tnp_1-associated SEP PF08059.13 GAK65855.1 - 1.8e-24 86.1 0.0 3.4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 GAK65855.1 - 3.4e-17 62.4 0.0 5.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 GAK65855.1 - 9.6e-16 57.3 0.3 1.8e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 UBA-like domain PTPRCAP PF15713.5 GAK65855.1 - 0.075 13.3 5.0 0.2 11.9 5.0 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PBP1_TM PF14812.6 GAK65855.1 - 1.7 9.0 6.4 1.3 9.5 3.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim17 PF02466.19 GAK65856.1 - 5.6e-09 36.4 9.7 1.2e-08 35.3 9.7 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 GAK65856.1 - 0.019 15.1 8.3 0.22 11.7 5.9 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III 5TM-5TMR_LYT PF07694.12 GAK65856.1 - 1.8 8.0 8.3 1.4 8.4 6.1 1.7 1 1 1 2 2 2 0 5TMR of 5TMR-LYT tRNA_bind PF01588.20 GAK65857.1 - 6.1e-27 93.6 0.0 1.3e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 GAK65857.1 - 2.6e-05 24.4 0.1 2.6e-05 24.4 0.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAK65857.1 - 0.0039 17.2 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAK65857.1 - 0.0048 16.7 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAK65857.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GAGA_bind PF06217.12 GAK65857.1 - 0.015 15.6 1.5 0.019 15.3 1.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 GAK65857.1 - 3.2 7.5 8.4 6.4 6.5 8.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 THOC2_N PF16134.5 GAK65857.1 - 3.5 6.1 9.7 5.6 5.5 9.7 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus adh_short PF00106.25 GAK65858.1 - 4.4e-06 26.3 0.0 0.033 13.6 0.0 3.2 3 1 0 3 3 3 2 short chain dehydrogenase DUF3425 PF11905.8 GAK65861.1 - 5.5e-37 126.5 0.0 9.9e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAK65861.1 - 2.3e-05 24.4 9.2 4.5e-05 23.5 9.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAK65861.1 - 1.1 9.4 12.2 2 8.6 12.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper UDPGP PF01704.18 GAK65862.1 - 1.1e-45 156.0 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_L4 PF00573.22 GAK65863.1 - 2.6e-41 141.4 0.6 4.7e-41 140.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAK65863.1 - 1.9e-29 101.6 3.3 7.2e-29 99.7 0.6 2.6 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain RCDG1 PF15725.5 GAK65863.1 - 1.1 9.7 5.3 0.68 10.4 0.1 2.8 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein CAP_N PF01213.19 GAK65864.1 - 0.46 9.9 3.8 0.37 10.2 0.3 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Aconitase PF00330.20 GAK65865.1 - 2.3e-153 511.5 0.0 2.9e-153 511.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAK65865.1 - 7.6e-42 142.7 0.1 1.8e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.13 GAK65865.1 - 0.02 13.6 0.1 0.067 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF521) MFS_1 PF07690.16 GAK65866.1 - 1.5e-30 106.3 48.4 8.2e-29 100.6 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK65866.1 - 1.5e-19 70.2 11.5 1.3e-18 67.2 10.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Chalcone_2 PF16035.5 GAK65867.1 - 2.4e-34 118.9 0.6 2e-22 80.0 0.0 2.5 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 GAK65867.1 - 1.2e-05 25.5 0.2 6.4e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 Chalcone isomerase-like DHC_N2 PF08393.13 GAK65867.1 - 0.056 12.6 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Acetyltransf_1 PF00583.25 GAK65868.1 - 6.8e-15 55.3 0.0 8.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK65868.1 - 3.4e-10 40.2 0.1 4.8e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAK65868.1 - 3.5e-10 39.9 0.0 4.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK65868.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAK65868.1 - 0.024 14.7 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAK65868.1 - 0.026 14.7 0.1 0.045 13.9 0.1 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 GAK65868.1 - 0.037 14.2 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TMEM154 PF15102.6 GAK65870.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family Macoilin PF09726.9 GAK65870.1 - 0.034 12.7 1.0 0.061 11.9 1.0 1.3 1 0 0 1 1 1 0 Macoilin family ADH_N PF08240.12 GAK65871.1 - 1.7e-26 92.3 4.8 2.8e-26 91.5 4.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK65871.1 - 5.6e-13 49.0 0.0 2.2e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAK65871.1 - 0.14 11.5 0.2 0.23 10.8 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain V-SNARE_C PF12352.8 GAK65872.1 - 0.012 15.9 2.6 1 9.7 0.4 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus PSD1 PF07587.11 GAK65872.1 - 0.03 13.8 0.7 0.03 13.8 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1553) Neur_chan_memb PF02932.16 GAK65872.1 - 0.14 12.2 4.0 0.22 11.5 4.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1490 PF07371.12 GAK65872.1 - 1.4 9.0 4.0 0.44 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Prefoldin_2 PF01920.20 GAK65873.1 - 2.6e-17 62.7 9.3 4.5e-17 61.9 9.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit EMP24_GP25L PF01105.24 GAK65873.1 - 0.12 12.3 5.5 1.1 9.1 0.7 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD WSD PF15613.6 GAK65873.1 - 0.15 12.6 4.0 0.51 10.8 0.4 2.2 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF4349 PF14257.6 GAK65873.1 - 0.29 10.5 12.9 56 3.1 12.8 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2408 PF10303.9 GAK65873.1 - 0.59 10.7 9.0 0.26 11.9 6.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) CLZ PF16526.5 GAK65873.1 - 1.9 8.9 9.3 0.076 13.4 2.0 2.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 GAK65873.1 - 2.8 8.5 8.9 6.2 7.4 1.8 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 GAK65873.1 - 6.9 6.7 11.2 84 3.2 9.7 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 GAK65873.1 - 8 5.7 13.1 11 5.3 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 GAK65873.1 - 9.4 6.1 14.8 9.3 6.1 4.6 2.4 2 0 0 2 2 2 0 Septum formation initiator RhoGEF PF00621.20 GAK65874.1 - 1.2e-12 48.5 0.0 4.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CSTF2_hinge PF14327.6 GAK65875.1 - 8.3e-34 115.9 2.1 8.3e-34 115.9 2.1 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 GAK65875.1 - 3.1e-23 81.4 0.0 5e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 GAK65875.1 - 1.9e-14 53.0 5.2 1.9e-14 53.0 5.2 2.7 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 GAK65875.1 - 0.00047 20.2 0.1 0.0011 19.0 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif Spo7_2_N PF15407.6 GAK65875.1 - 0.18 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 DUF1631 PF07793.11 GAK65875.1 - 4.3 5.6 7.0 5.8 5.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF2315 PF10231.9 GAK65876.1 - 1.1e-21 77.2 2.4 4e-15 56.0 1.6 2.4 2 1 0 2 2 2 2 Apoptogenic protein 1 Death PF00531.22 GAK65876.1 - 0.0081 16.3 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 Death domain Mis14 PF08641.12 GAK65878.1 - 1.6e-07 31.7 4.1 3e-07 30.8 4.1 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like DUF2935 PF11155.8 GAK65878.1 - 0.014 15.7 0.2 0.085 13.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Tir_receptor_C PF07489.11 GAK65878.1 - 0.1 12.6 0.6 0.14 12.1 0.6 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus V_ATPase_I PF01496.19 GAK65878.1 - 0.21 9.5 0.7 0.22 9.4 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.11 GAK65878.1 - 0.31 11.1 2.8 0.44 10.6 1.3 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.10 GAK65878.1 - 0.76 10.0 8.5 10 6.4 5.7 2.5 2 1 0 2 2 2 0 Cortexillin I, coiled coil MFS_1 PF07690.16 GAK65879.1 - 2.3e-08 33.4 27.9 2.8e-08 33.1 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.23 GAK65880.1 - 0.082 13.0 1.2 0.16 12.1 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_2 PF13923.6 GAK65880.1 - 0.99 9.3 7.8 1.6 8.6 7.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK65880.1 - 1.4 8.8 7.4 2.3 8.2 7.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1674 PF07896.12 GAK65881.1 - 5.6e-18 65.2 4.4 5.6e-18 65.2 4.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) AAA_11 PF13086.6 GAK65882.1 - 0.039 13.7 7.1 0.062 13.1 7.1 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 GAK65882.1 - 0.88 9.7 5.0 1.8 8.7 5.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RQC PF09382.10 GAK65883.1 - 1.1e-23 83.2 0.1 2.6e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 GAK65883.1 - 1.1e-19 70.8 0.0 2.3e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK65883.1 - 2.8e-18 66.3 0.0 4.6e-17 62.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAK65883.1 - 1.2e-15 57.9 6.4 1.2e-15 57.9 6.4 2.3 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 GAK65883.1 - 2.5e-05 24.2 0.0 6.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 GAK65883.1 - 0.0014 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_Sgs1 PF11408.8 GAK65883.1 - 0.038 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase UME PF08064.13 GAK65883.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain Radial_spoke PF04712.12 GAK65883.1 - 1.1 8.2 3.6 1.8 7.4 3.6 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Sigma70_ner PF04546.13 GAK65883.1 - 4.8 7.0 10.6 0.062 13.2 2.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Prenyltrans PF00432.21 GAK65884.1 - 0.081 12.7 0.3 3.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat B56 PF01603.20 GAK65885.1 - 2e-194 646.3 9.2 2.4e-194 646.0 9.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) LamB_YcsF PF03746.16 GAK65886.1 - 4.6e-86 288.4 0.0 5.2e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 GAK65887.1 - 1e-68 231.8 0.1 1.7e-68 231.1 0.1 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 GAK65887.1 - 1.3e-54 184.9 0.0 2.4e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAK65887.1 - 2.6e-33 114.8 0.0 1.1e-32 112.8 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 GAK65887.1 - 3.5e-32 111.8 0.1 1.1e-31 110.2 0.0 1.9 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 GAK65887.1 - 4.9e-28 97.4 0.0 1.6e-27 95.8 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAK65887.1 - 3.8e-13 49.1 0.4 9.7e-13 47.8 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAK65887.1 - 1.7e-09 37.5 0.0 4.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAK65887.1 - 1.1e-05 25.0 0.1 3.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAK65887.1 - 0.00029 20.9 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAK65887.1 - 0.00042 20.0 0.0 0.0019 17.8 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 GAK65887.1 - 0.0036 16.8 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAK65887.1 - 0.0042 16.9 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 GAK65887.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATP-grasp_4 PF13535.6 GAK65887.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Cornichon PF03311.14 GAK65888.1 - 1e-46 158.2 6.1 1.2e-46 158.0 6.1 1.1 1 0 0 1 1 1 1 Cornichon protein PDCD2_C PF04194.13 GAK65889.1 - 6.4e-32 111.0 12.2 1.3e-30 106.8 0.0 3.9 4 0 0 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain EcsC PF12787.7 GAK65889.1 - 0.002 17.8 0.3 0.0052 16.5 0.1 1.7 2 0 0 2 2 2 1 EcsC protein family TFIIA PF03153.13 GAK65889.1 - 0.049 13.6 6.9 0.053 13.5 4.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 GAK65889.1 - 3.7 7.2 18.8 4 7.1 4.4 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RPA43_OB PF17875.1 GAK65889.1 - 7.7 7.2 6.2 13 6.5 0.5 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I MFS_1 PF07690.16 GAK65890.1 - 4.3e-10 39.0 22.2 9.7e-09 34.6 13.5 3.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAK65890.1 - 0.00051 18.7 0.6 0.00051 18.7 0.6 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 GAK65890.1 - 0.0076 15.2 0.0 0.014 14.3 0.0 1.5 1 1 0 1 1 1 1 MFS_1 like family PrgI PF12666.7 GAK65890.1 - 0.11 13.3 1.3 0.6 10.9 0.1 2.7 2 0 0 2 2 2 0 PrgI family protein NIPSNAP PF07978.13 GAK65890.1 - 0.13 12.5 1.1 0.32 11.3 0.2 2.1 2 0 0 2 2 2 0 NIPSNAP GTP_EFTU PF00009.27 GAK65891.1 - 2.1e-46 157.9 0.0 2.9e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GAK65891.1 - 7.2e-35 120.2 4.2 1.2e-34 119.5 4.2 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 GAK65891.1 - 1.2e-24 86.5 0.0 2.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAK65891.1 - 1.7e-20 72.8 0.0 3.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 GAK65891.1 - 2.2e-06 27.7 0.0 4.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAK65891.1 - 5.2e-05 23.5 0.1 0.0001 22.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAK65891.1 - 8.7e-05 22.5 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 GAK65891.1 - 0.0044 16.6 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAK65891.1 - 0.007 16.6 0.0 0.027 14.7 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAK65891.1 - 0.014 15.4 0.0 2 8.4 0.0 2.2 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 GAK65891.1 - 0.022 14.2 0.0 0.053 13.0 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1770 PF08589.10 GAK65891.1 - 0.11 13.5 0.0 0.25 12.3 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Glutaredoxin PF00462.24 GAK65892.1 - 4.3e-16 58.9 0.1 6.5e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin bZIP_1 PF00170.21 GAK65893.1 - 0.00016 21.7 8.1 0.00031 20.8 8.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAK65893.1 - 0.026 14.6 6.2 0.056 13.5 6.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper SAGA-Tad1 PF12767.7 GAK65893.1 - 1.5 8.5 7.1 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Fasciclin PF02469.22 GAK65894.1 - 4.3e-23 81.9 0.1 3.6e-14 53.1 0.0 3.4 3 0 0 3 3 3 3 Fasciclin domain COesterase PF00135.28 GAK65895.1 - 5.8e-72 243.2 0.0 2.1e-36 125.9 0.0 2.7 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK65895.1 - 4.2e-07 30.0 4.0 0.0039 17.1 0.5 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold XPG_I PF00867.18 GAK65896.1 - 2.2e-19 69.6 0.0 1.7e-18 66.7 0.0 2.3 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAK65896.1 - 6.8e-05 23.3 0.0 0.00066 20.1 0.0 2.5 2 1 0 2 2 2 1 XPG N-terminal domain Abhydrolase_1 PF00561.20 GAK65897.1 - 1e-06 28.6 0.1 1.1e-05 25.2 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK65897.1 - 1.3e-05 24.6 0.4 0.00074 18.8 0.1 2.6 1 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 GAK65897.1 - 0.00028 20.1 0.0 0.00043 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 GAK65897.1 - 0.00057 19.4 0.1 0.077 12.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF915 PF06028.11 GAK65897.1 - 0.021 14.2 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2423 PF10338.9 GAK65898.1 - 1.8e-13 50.5 6.3 3.2e-13 49.7 6.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ank_2 PF12796.7 GAK65899.1 - 1.5e-42 144.1 0.9 1.3e-14 54.6 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK65899.1 - 2.4e-31 107.7 1.7 4.1e-09 36.8 0.1 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 GAK65899.1 - 5.6e-24 85.8 18.2 4.9e-09 36.6 0.8 3.6 2 1 2 4 4 4 3 SPX domain Ank_3 PF13606.6 GAK65899.1 - 8.1e-22 75.0 4.0 0.012 16.0 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 GAK65899.1 - 5.1e-20 71.0 9.0 0.0016 18.8 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 GAK65899.1 - 1.3e-19 70.0 6.2 0.01 16.1 0.0 6.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) GDPD PF03009.17 GAK65899.1 - 1.3e-13 51.3 0.0 5.8e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Peripla_BP_2 PF01497.18 GAK65899.1 - 0.043 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein CRM1_C PF08767.11 GAK65900.1 - 1e-130 435.6 1.3 8.8e-130 432.5 0.0 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 GAK65900.1 - 1.4e-40 138.8 0.7 1.4e-40 138.8 0.7 3.8 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAK65900.1 - 2.7e-34 116.6 4.2 6.2e-34 115.5 4.2 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAK65900.1 - 3.7e-31 107.0 0.8 1.5e-30 105.1 0.8 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 GAK65900.1 - 1.5e-20 72.4 0.9 4.5e-20 70.9 0.9 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 GAK65900.1 - 1.2e-15 57.2 0.7 6.2e-15 54.9 0.7 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain V-SNARE_C PF12352.8 GAK65901.1 - 3.5e-17 62.5 2.4 3.9e-17 62.3 0.7 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus End3 PF12761.7 GAK65901.1 - 0.048 13.8 0.0 0.16 12.1 0.0 1.7 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 ABC_tran_CTD PF16326.5 GAK65901.1 - 0.048 13.9 0.1 0.36 11.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 GAK65901.1 - 0.1 12.7 1.1 19 5.3 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nucleoporin_C PF03177.14 GAK65902.1 - 1.1e-128 430.7 0.0 1.4e-128 430.3 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal WD40 PF00400.32 GAK65902.1 - 8.9e-18 64.3 20.8 4.1e-07 30.6 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 GAK65902.1 - 8.9e-15 54.4 0.0 6.7e-14 51.5 0.0 2.3 3 0 0 3 3 3 1 Nup133 N terminal like Fungal_trans PF04082.18 GAK65902.1 - 8.5e-12 44.7 0.0 9.2e-09 34.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain ANAPC4_WD40 PF12894.7 GAK65902.1 - 1.3e-06 28.6 0.4 0.23 11.8 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 GAK65902.1 - 0.0073 16.2 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Ge1_WD40 PF16529.5 GAK65902.1 - 0.04 12.9 0.1 3.1 6.6 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C2H2 PF00096.26 GAK65902.1 - 0.13 12.7 6.6 0.038 14.5 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK65902.1 - 4.9 8.3 7.4 0.2 12.6 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3891 PF13030.6 GAK65903.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3891) DUF2087 PF09860.9 GAK65908.1 - 0.081 13.1 0.5 0.62 10.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF2786 PF10979.8 GAK65909.1 - 2.8e-12 46.3 0.4 2.8e-12 46.3 0.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Guanylate_kin PF00625.21 GAK65910.1 - 8.6e-58 195.0 0.0 1.1e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 GAK65910.1 - 1.2e-07 32.3 0.1 3.3e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAK65910.1 - 6.4e-05 23.2 0.0 0.00025 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAK65910.1 - 0.00011 22.7 0.0 0.0012 19.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAK65910.1 - 0.00016 21.6 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GAK65910.1 - 0.00016 21.7 0.0 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 GAK65910.1 - 0.00082 19.6 0.0 0.0097 16.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAK65910.1 - 0.0027 18.2 0.0 0.0063 17.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter NTPase_1 PF03266.15 GAK65910.1 - 0.0028 17.6 0.0 0.0058 16.5 0.0 1.6 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 GAK65910.1 - 0.0034 17.8 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 GAK65910.1 - 0.0036 17.3 0.0 0.077 12.9 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 GAK65910.1 - 0.0037 17.2 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 GAK65910.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 GAK65910.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAK65910.1 - 0.0061 16.8 0.1 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAK65910.1 - 0.0077 16.2 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAK65910.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 GAK65910.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 GAK65910.1 - 0.011 15.5 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAK65910.1 - 0.024 13.8 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 GAK65910.1 - 0.028 14.8 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 GAK65910.1 - 0.031 14.6 0.0 4.1 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAK65910.1 - 0.035 13.8 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 Thymidylate kinase KAP_NTPase PF07693.14 GAK65910.1 - 0.046 13.0 0.0 0.054 12.7 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 GAK65910.1 - 0.056 13.1 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAK65910.1 - 0.063 12.3 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PCMT PF01135.19 GAK65911.1 - 3.2e-67 226.3 0.0 3.8e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GAK65911.1 - 2.1e-07 31.5 0.0 4.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK65911.1 - 3.2e-07 30.3 0.0 4.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK65911.1 - 8.1e-05 23.2 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAK65911.1 - 0.0017 17.8 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 GAK65911.1 - 0.0023 17.9 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK65911.1 - 0.003 17.4 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK65911.1 - 0.023 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 GAK65911.1 - 0.037 14.0 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 GAK65911.1 - 0.084 11.8 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) UQ_con PF00179.26 GAK65912.1 - 5.7e-39 133.0 0.1 7.9e-39 132.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAK65912.1 - 0.031 14.6 0.3 0.097 13.0 0.3 1.8 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 GAK65912.1 - 0.05 13.5 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Exo_endo_phos PF03372.23 GAK65913.1 - 1.2e-20 74.0 0.2 1.8e-20 73.5 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 GAK65914.1 - 1.9e-11 44.3 8.8 0.00062 20.5 0.1 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK65914.1 - 3.4e-08 33.7 0.0 0.00053 20.2 0.0 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Vps54 PF07928.12 GAK65915.1 - 5e-53 179.1 0.7 1.5e-52 177.6 0.7 1.9 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 GAK65915.1 - 3.2e-07 29.9 1.4 4.7e-07 29.4 0.2 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex TPR_19 PF14559.6 GAK65915.1 - 0.014 15.9 0.1 0.014 15.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK65915.1 - 0.039 14.8 0.7 0.4 11.6 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2451 PF10474.9 GAK65915.1 - 0.043 13.6 0.3 0.092 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Sec15 PF04091.12 GAK65915.1 - 0.097 12.1 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like TPR_4 PF07721.14 GAK65915.1 - 0.28 11.9 4.8 0.85 10.4 0.5 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1356 PF07092.12 GAK65916.1 - 0.0016 17.8 0.8 0.0027 17.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 GAK65916.1 - 0.012 16.2 0.1 0.026 15.0 0.1 1.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein Peptidase_S8 PF00082.22 GAK65917.1 - 5.9e-38 130.8 2.3 8.3e-38 130.3 2.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 GAK65917.1 - 3.1e-27 94.4 0.1 7.6e-27 93.2 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 GAK65917.1 - 0.14 12.9 8.1 0.22 12.3 0.0 2.9 1 1 1 2 2 2 0 Peptidase S8 pro-domain MIP PF00230.20 GAK65918.1 - 5.2e-45 153.9 13.5 7.2e-45 153.5 13.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein Lactamase_B_6 PF16661.5 GAK65919.1 - 3.5e-48 163.6 0.0 1.8e-45 154.8 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 GAK65919.1 - 9e-35 120.4 0.2 3.2e-34 118.6 0.2 2.0 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 GAK65919.1 - 6.5e-18 65.0 0.0 3.6e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 GAK65919.1 - 3.8e-05 23.5 0.0 9.9e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 GAK65919.1 - 0.01 15.4 0.3 0.055 13.0 0.1 2.2 2 1 0 2 2 2 0 Beta-lactamase superfamily domain fn3_2 PF16893.5 GAK65920.1 - 1.3e-37 127.8 0.1 2.3e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 GAK65920.1 - 5.6e-26 90.2 0.1 8.8e-26 89.6 0.1 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 GAK65920.1 - 0.00039 20.3 0.1 0.0014 18.6 0.0 2.0 2 1 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 GAK65920.1 - 0.00096 19.5 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 GAK65920.1 - 0.0021 18.4 0.1 0.0085 16.4 0.1 2.1 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 GAK65920.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 GAK65920.1 - 0.1 13.0 0.0 0.44 11.0 0.0 2.0 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain F-box PF00646.33 GAK65921.1 - 1.5e-07 31.1 0.3 2.7e-07 30.3 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAK65921.1 - 1.9e-07 30.9 0.8 3.4e-07 30.0 0.8 1.4 1 0 0 1 1 1 1 F-box-like Lactamase_B_3 PF13483.6 GAK65922.1 - 1.5e-05 25.0 0.0 7.1e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GAK65922.1 - 0.061 12.8 0.3 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain CitT PF12431.8 GAK65922.1 - 0.16 12.4 0.5 5 7.6 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator P34-Arc PF04045.14 GAK65923.1 - 1.8e-107 358.5 0.0 2.3e-107 358.2 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc TFIIA PF03153.13 GAK65924.1 - 0.048 13.7 2.4 0.062 13.3 2.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUP50 PF08911.11 GAK65924.1 - 0.76 10.5 8.0 0.22 12.2 1.0 3.0 3 0 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) FYDLN_acid PF09538.10 GAK65924.1 - 4.2 8.1 9.7 1.1 9.9 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PGA2 PF07543.12 GAK65924.1 - 6.1 6.8 8.3 1.2e+02 2.6 0.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 TEA PF01285.18 GAK65926.1 - 5.9e-30 103.1 0.0 1.4e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain Pkinase_Tyr PF07714.17 GAK65927.1 - 1.5e-44 152.2 0.0 2.1e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAK65927.1 - 4e-42 144.4 0.0 5.7e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAK65927.1 - 0.0099 14.7 0.4 0.077 11.8 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase Sec66 PF09802.9 GAK65928.1 - 5.5e-54 182.5 0.0 8.9e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Phage_Mu_F PF04233.14 GAK65928.1 - 0.043 14.5 1.8 0.19 12.5 1.1 2.2 2 0 0 2 2 2 0 Phage Mu protein F like protein Spt20 PF12090.8 GAK65928.1 - 3 7.4 13.0 4.9 6.7 13.0 1.3 1 0 0 1 1 1 0 Spt20 family RasGEF PF00617.19 GAK65929.1 - 4.7e-61 206.1 2.0 6.2e-60 202.4 0.1 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 GAK65929.1 - 4.8e-29 100.7 0.2 1.2e-28 99.4 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 GAK65929.1 - 6.4e-14 51.3 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK65929.1 - 2.1e-10 40.3 0.0 4.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAK65929.1 - 2.3e-10 40.0 0.0 4.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Dynein_C PF18199.1 GAK65929.1 - 0.021 14.0 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain SAE2 PF08573.10 GAK65930.1 - 3.9e-09 37.6 8.2 1.7e-07 32.3 0.2 3.3 2 1 1 3 3 3 3 DNA repair protein endonuclease SAE2/CtIP C-terminus UEV PF05743.13 GAK65931.1 - 3.4e-33 114.1 0.0 5.1e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 GAK65931.1 - 1.8e-28 98.2 1.7 5.5e-28 96.7 0.4 2.1 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 GAK65931.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme zf-Mss51 PF13824.6 GAK65932.1 - 2.1e-22 79.0 1.2 4.2e-22 78.0 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.11 GAK65932.1 - 0.18 11.5 1.3 13 5.5 0.3 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain GDP_Man_Dehyd PF16363.5 GAK65933.1 - 6.5e-49 167.1 0.0 5.3e-44 151.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAK65933.1 - 1.9e-45 155.2 0.0 3.1e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK65933.1 - 2e-09 36.9 0.0 3.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAK65933.1 - 2.9e-08 33.2 0.0 0.00013 21.3 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 GAK65933.1 - 6e-05 22.3 0.0 0.00016 20.9 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAK65933.1 - 0.00011 21.5 0.1 0.0016 17.7 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Lactamase_B_2 PF12706.7 GAK65934.1 - 5e-19 68.6 0.0 3.6e-18 65.8 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAK65934.1 - 3.5e-06 27.0 0.0 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAK65934.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Fungal_trans PF04082.18 GAK65935.1 - 5e-20 71.6 0.0 8.2e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK65935.1 - 2.3e-06 27.6 8.7 4.7e-06 26.6 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4188 PF13826.6 GAK65936.1 - 1.7e-24 86.4 0.0 2.5e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) ABC_tran_CTD PF16326.5 GAK65937.1 - 0.085 13.1 9.0 0.043 14.1 4.9 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 GAK65937.1 - 0.23 11.5 7.6 1.2 9.2 1.0 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 GAK65937.1 - 1.5 8.0 11.3 0.42 9.8 0.5 2.7 3 0 0 3 3 3 0 HAP1 N-terminal conserved region DASH_Hsk3 PF08227.11 GAK65937.1 - 4.5 7.7 5.8 3.7 8.0 3.6 2.1 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DivIC PF04977.15 GAK65937.1 - 6.1 6.7 12.2 5.4 6.9 0.4 3.0 2 1 1 3 3 3 0 Septum formation initiator CHORD PF04968.12 GAK65939.1 - 3e-48 162.4 12.7 5.1e-24 84.8 4.8 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.16 GAK65939.1 - 1.6e-07 32.2 0.0 2.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 CS domain BTK PF00779.19 GAK65939.1 - 0.01 15.7 10.3 0.15 11.9 2.6 3.3 3 1 0 3 3 3 0 BTK motif AAA PF00004.29 GAK65940.1 - 8.6e-14 52.1 0.0 2.6e-13 50.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAK65940.1 - 0.00022 21.0 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 GAK65940.1 - 0.00062 20.1 0.1 0.0023 18.2 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 GAK65940.1 - 0.00078 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK65940.1 - 0.0013 19.2 0.0 0.17 12.3 0.1 3.3 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 GAK65940.1 - 0.0022 18.0 0.0 0.076 12.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 GAK65940.1 - 0.011 15.3 0.2 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 GAK65940.1 - 0.08 13.2 0.0 0.58 10.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 GAK65940.1 - 0.082 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAK65940.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAK65940.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 GAK65940.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAK65940.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 GAK65940.1 - 0.22 11.4 0.2 0.7 9.8 0.0 1.9 1 1 1 2 2 2 0 NTPase Carboxyl_trans PF01039.22 GAK65941.1 - 3e-139 464.9 0.2 3.7e-139 464.6 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 GAK65941.1 - 0.0095 15.4 0.1 0.51 9.8 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) AAA PF00004.29 GAK65942.1 - 2.1e-17 63.8 0.0 5.9e-17 62.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAK65942.1 - 6.7e-06 26.4 1.3 0.0015 18.8 0.6 3.6 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 GAK65942.1 - 6.9e-05 22.9 0.3 0.00042 20.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAK65942.1 - 0.00039 20.8 0.2 0.0013 19.2 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 GAK65942.1 - 0.026 13.9 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAK65942.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAK65942.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 GAK65942.1 - 0.053 14.1 0.0 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 GAK65942.1 - 0.059 12.6 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 GAK65942.1 - 0.081 13.2 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 GAK65942.1 - 0.097 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAK65942.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 GAK65942.1 - 0.15 12.4 0.2 0.45 10.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAK65942.1 - 0.65 9.7 3.1 0.36 10.5 0.6 1.9 2 1 0 2 2 2 0 AAA domain Peptidase_S15 PF02129.18 GAK65943.1 - 6.8e-34 117.7 0.1 7.8e-33 114.2 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAK65943.1 - 6.1e-13 49.2 0.0 9.6e-09 35.5 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Zip PF02535.22 GAK65944.1 - 6e-51 173.6 1.4 7.7e-51 173.3 1.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MIG-14_Wnt-bd PF06664.12 GAK65944.1 - 0.047 12.9 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF1772 PF08592.11 GAK65944.1 - 0.14 12.5 0.0 0.14 12.5 0.0 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF1772) Cation_ATPase_C PF00689.21 GAK65944.1 - 0.16 11.7 2.2 0.18 11.5 0.0 2.1 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus ERG4_ERG24 PF01222.17 GAK65946.1 - 2e-143 478.2 6.2 2.4e-143 478.0 6.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAK65946.1 - 2.3e-06 27.3 0.3 5.5e-06 26.1 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 GAK65946.1 - 0.00066 20.1 0.3 0.0027 18.1 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 GAK65946.1 - 0.03 14.7 0.0 0.098 13.1 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ORC6 PF05460.13 GAK65946.1 - 7.3 5.7 9.9 9.9 5.3 9.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2012 PF09430.10 GAK65947.1 - 9.8e-38 129.0 0.0 1.4e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 GAK65947.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Atx10homo_assoc PF09759.9 GAK65948.1 - 8.6e-21 73.8 0.2 2.9e-18 65.7 0.0 3.8 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Glyco_trans_2_3 PF13632.6 GAK65949.1 - 1.5e-50 171.9 4.5 1.5e-50 171.9 4.5 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK65949.1 - 2.5e-07 30.8 0.0 4.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAK65949.1 - 0.00021 21.2 0.0 0.0039 17.0 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAK65949.1 - 0.0049 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 GAK65950.1 - 1.4e-14 53.9 0.2 2.5e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MMM1 PF10296.9 GAK65951.1 - 2.8e-81 273.1 0.0 2.2e-80 270.2 0.0 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Cyt-b5 PF00173.28 GAK65952.1 - 1.6e-22 79.4 1.2 3.3e-22 78.4 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 GAK65952.1 - 5.7e-15 55.8 15.2 5.7e-15 55.8 15.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PBS_linker_poly PF00427.21 GAK65952.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Lactamase_B_2 PF12706.7 GAK65953.1 - 1.9e-13 50.4 5.8 2.8e-11 43.3 5.9 3.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 GAK65953.1 - 5.6e-13 48.4 0.0 1.6e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 GAK65953.1 - 0.00013 22.1 3.9 0.00042 20.4 3.9 1.9 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PCNP PF15473.6 GAK65953.1 - 0.046 14.5 0.1 0.046 14.5 0.1 2.9 4 0 0 4 4 4 0 PEST, proteolytic signal-containing nuclear protein family Spore_III_AF PF09581.10 GAK65955.1 - 0.88 9.6 3.8 2.8 7.9 3.8 1.9 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Dynamin_N PF00350.23 GAK65957.1 - 1.3e-19 70.9 0.0 2.6e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 GAK65957.1 - 7.3e-06 25.4 0.0 0.00012 21.4 0.0 2.4 2 1 0 2 2 2 1 Dynamin central region AAA_28 PF13521.6 GAK65957.1 - 0.021 15.1 0.5 0.074 13.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAK65957.1 - 0.056 13.5 0.1 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase BshC PF10079.9 GAK65957.1 - 0.11 11.2 0.1 0.24 10.1 0.0 1.5 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC GOLGA2L5 PF15070.6 GAK65957.1 - 0.12 11.0 0.1 9.3 4.8 0.1 2.1 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 APG9 PF04109.16 GAK65957.1 - 0.15 11.0 0.3 0.24 10.4 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg9 RCC1 PF00415.18 GAK65958.1 - 2.1e-24 85.8 3.2 8.4e-05 23.1 0.0 7.3 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAK65958.1 - 3.7e-16 58.5 19.5 7.4e-05 22.4 0.2 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat KH_1 PF00013.29 GAK65959.1 - 8.2e-41 137.7 7.5 1.6e-16 59.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAK65959.1 - 1.3e-10 40.9 6.9 0.0028 17.4 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAK65959.1 - 4.7e-08 32.8 0.5 0.066 13.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAK65959.1 - 0.00059 19.9 3.2 0.11 12.5 0.2 3.3 3 0 0 3 3 3 1 NusA-like KH domain DUF202 PF02656.15 GAK65960.1 - 2.1e-20 72.9 0.5 8.1e-20 71.0 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2607 PF10795.9 GAK65960.1 - 0.037 14.2 0.5 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) DnaJ PF00226.31 GAK65961.1 - 2.9e-18 65.8 1.8 5.8e-18 64.8 1.8 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 GAK65961.1 - 0.064 13.5 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 GAK65961.1 - 0.77 9.9 6.0 1.4 9.1 6.0 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PAN_4 PF14295.6 GAK65962.1 - 0.00069 19.5 1.4 0.0014 18.5 1.4 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 GAK65962.1 - 0.0018 17.7 1.1 0.0046 16.4 0.4 1.9 2 1 0 2 2 2 1 Fringe-like Acyltransferase PF01553.21 GAK65963.1 - 0.00099 18.7 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase FAR1 PF03101.15 GAK65964.1 - 2e-05 25.2 0.1 4.4e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 GAK65964.1 - 0.0094 16.3 0.0 0.03 14.7 0.0 2.0 1 0 0 1 1 1 1 Transcription factor AFT zf-C2H2_10 PF16588.5 GAK65964.1 - 0.041 13.6 3.9 0.075 12.8 3.9 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger DDE_Tnp_1_6 PF13751.6 GAK65964.1 - 0.059 13.6 0.4 0.15 12.3 0.4 1.6 1 0 0 1 1 1 0 Transposase DDE domain zf-CCHC PF00098.23 GAK65964.1 - 0.15 12.1 3.2 0.48 10.6 3.2 1.8 1 0 0 1 1 1 0 Zinc knuckle BPL_LplA_LipB PF03099.19 GAK65967.1 - 2.9e-05 24.0 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Opy2 PF09463.10 GAK65968.1 - 0.00046 20.4 18.8 0.0007 19.9 18.8 1.3 1 0 0 1 1 1 1 Opy2 protein NINJA_B PF16136.5 GAK65968.1 - 0.0087 16.4 1.5 0.24 11.8 0.2 2.4 2 0 0 2 2 2 1 Putative nuclear localisation signal DUF4381 PF14316.6 GAK65968.1 - 0.018 15.3 2.3 0.031 14.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TraL PF07178.11 GAK65968.1 - 0.21 12.1 0.1 0.37 11.3 0.1 1.3 1 0 0 1 1 1 0 TraL protein DUF3301 PF11743.8 GAK65968.1 - 0.23 11.1 1.2 3.3 7.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Ephrin_rec_like PF07699.13 GAK65968.1 - 8.3 6.3 11.8 17 5.3 11.8 1.5 1 0 0 1 1 1 0 Putative ephrin-receptor like p450 PF00067.22 GAK65969.1 - 2e-75 254.4 0.0 2.8e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.15 GAK65970.1 - 6.4e-131 437.2 39.2 7.4e-131 436.9 39.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1338 PF07063.13 GAK65971.1 - 1.2e-110 369.7 0.0 1.5e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Aldedh PF00171.22 GAK65972.1 - 1.3e-120 403.0 0.1 1.6e-120 402.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAK65972.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRM_1 PF00076.22 GAK65973.1 - 4.2e-07 29.7 0.0 8.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 GAK65973.1 - 0.18 12.7 0.0 0.42 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. MgsA_C PF12002.8 GAK65974.1 - 6.4e-49 166.1 0.0 1.7e-48 164.7 0.0 1.7 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 GAK65974.1 - 1.6e-24 86.1 0.3 4.3e-24 84.6 0.3 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 GAK65974.1 - 3.7e-14 53.3 0.0 1.4e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAK65974.1 - 3.8e-13 49.5 0.0 9.8e-12 44.9 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAK65974.1 - 3.5e-08 34.0 2.6 0.0002 21.8 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAK65974.1 - 7.5e-07 29.5 0.2 7.2e-06 26.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAK65974.1 - 1.6e-06 28.2 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAK65974.1 - 1.7e-06 28.1 0.2 1.2e-05 25.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAK65974.1 - 3e-05 23.5 0.2 0.034 13.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAK65974.1 - 0.0002 21.1 0.7 0.00093 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAK65974.1 - 0.00089 19.8 0.0 0.0018 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAK65974.1 - 0.0013 18.4 0.3 0.014 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 GAK65974.1 - 0.0014 18.8 0.0 0.0046 17.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 GAK65974.1 - 0.002 17.8 0.1 1.6 8.4 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 GAK65974.1 - 0.0028 18.2 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Sgf11 PF08209.11 GAK65974.1 - 0.0032 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) AAA_28 PF13521.6 GAK65974.1 - 0.004 17.4 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAK65974.1 - 0.0048 17.1 0.3 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain XAF1_C PF18608.1 GAK65974.1 - 0.005 16.4 3.6 0.011 15.3 3.6 1.5 1 0 0 1 1 1 1 XIAP-associated factor 1 C-terminal domain TniB PF05621.11 GAK65974.1 - 0.0056 16.1 0.0 0.083 12.3 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein NB-ARC PF00931.22 GAK65974.1 - 0.0072 15.5 0.1 0.72 9.0 0.0 2.1 1 1 1 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 GAK65974.1 - 0.0086 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK65974.1 - 0.012 16.0 1.2 0.95 9.8 0.3 2.5 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 GAK65974.1 - 0.025 13.8 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAK65974.1 - 0.042 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 GAK65974.1 - 0.043 13.6 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 GAK65974.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAK65974.1 - 0.067 13.1 0.0 5.9 6.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 GAK65974.1 - 0.073 12.9 0.3 0.18 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GAK65974.1 - 0.079 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 GAK65974.1 - 0.085 12.8 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Rer1 PF03248.13 GAK65975.1 - 1.5e-77 259.2 0.0 1.8e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 GAK65975.1 - 0.3 10.7 4.1 0.091 12.4 0.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pyr_redox_2 PF07992.14 GAK65976.1 - 1.1e-38 133.1 0.0 1.8e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK65976.1 - 6.3e-13 49.1 0.4 2.5e-07 31.1 0.1 3.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 GAK65976.1 - 4.3e-12 44.7 3.2 1.1e-05 24.6 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAK65976.1 - 3.8e-10 38.9 3.0 0.00014 21.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAK65976.1 - 4.4e-10 39.9 0.3 0.00032 21.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAK65976.1 - 5e-08 32.1 2.3 0.0015 18.0 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAK65976.1 - 2.7e-05 23.9 2.4 0.018 14.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 GAK65976.1 - 0.0071 15.6 2.5 1 8.6 3.2 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAK65976.1 - 0.019 15.4 0.8 1.1 9.8 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding ATP19 PF11022.8 GAK65977.1 - 1.2e-24 86.5 0.2 3.6e-24 84.9 0.2 1.8 1 0 0 1 1 1 1 ATP synthase subunit K Yae1_N PF09811.9 GAK65978.1 - 9.2e-11 41.3 0.8 1.8e-10 40.4 0.8 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SIMPL PF04402.14 GAK65978.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF541) DJ-1_PfpI PF01965.24 GAK65979.1 - 3.1e-42 144.2 0.1 3.5e-42 144.0 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 GAK65979.1 - 0.00071 19.2 0.2 0.0011 18.6 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 GAK65979.1 - 0.00084 19.0 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 GAK65979.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.6 2 0 0 2 2 2 1 ThiJ/PfpI family-like SNO PF01174.19 GAK65979.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family TFIIA_gamma_N PF02268.16 GAK65980.1 - 4.4e-21 74.6 0.0 6.5e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 GAK65980.1 - 4e-19 68.5 0.4 6e-19 67.9 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2841 PF11001.8 GAK65981.1 - 1.9e-38 131.3 0.1 1.9e-38 131.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) CRAL_TRIO PF00650.20 GAK65982.1 - 5.6e-19 68.4 0.0 8.8e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain adh_short_C2 PF13561.6 GAK65983.1 - 4.5e-38 131.1 0.4 5.2e-38 130.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK65983.1 - 1.3e-26 93.3 0.1 1.6e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK65983.1 - 0.00041 20.3 1.5 0.0016 18.4 1.5 1.9 1 1 0 1 1 1 1 KR domain SNF2_N PF00176.23 GAK65984.1 - 3.6e-59 200.2 0.0 7.2e-59 199.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK65984.1 - 2.3e-14 53.7 0.0 4.3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK65984.1 - 2.1e-10 40.9 0.0 4.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAK65984.1 - 2e-08 34.2 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAK65984.1 - 9.5e-05 21.7 0.1 0.00016 20.9 0.1 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 GAK65984.1 - 0.0017 17.6 0.1 0.0027 16.9 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 GAK65984.1 - 0.072 12.0 0.2 0.29 10.0 0.2 1.9 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 PH PF00169.29 GAK65985.1 - 1.1e-06 29.1 0.0 2.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 PH domain CSRNP_N PF16019.5 GAK65985.1 - 0.0054 16.7 0.2 0.0054 16.7 0.2 2.0 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus AIP3 PF03915.13 GAK65985.1 - 0.046 12.8 3.9 0.082 12.0 3.9 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Glycos_transf_4 PF00953.21 GAK65986.1 - 7.9e-35 120.2 4.3 7.9e-35 120.2 4.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 TFIIE_alpha PF02002.17 GAK65987.1 - 2.2e-11 43.5 1.3 6.7e-11 42.0 1.1 1.8 2 0 0 2 2 2 1 TFIIE alpha subunit DASH_Dam1 PF08653.10 GAK65987.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Cupin_8 PF13621.6 GAK65988.1 - 1.9e-44 152.3 0.0 4.2e-43 147.9 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAK65988.1 - 0.005 16.3 0.0 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein Zn_clus PF00172.18 GAK65989.1 - 1.2e-06 28.5 10.7 1.2e-06 28.5 10.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAS PF13851.6 GAK65989.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ion_trans PF00520.31 GAK65990.1 - 4.6e-05 22.8 18.9 8.3e-05 21.9 18.9 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GAK65990.1 - 0.025 13.3 12.3 0.13 10.9 12.3 2.0 1 1 0 1 1 1 0 Polycystin cation channel Abhydrolase_9_N PF15420.6 GAK65990.1 - 0.035 14.1 0.0 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus UQ_con PF00179.26 GAK65991.1 - 5.5e-47 158.9 0.0 6.1e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAK65991.1 - 0.0027 17.4 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAK65991.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 GAK65991.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain WH1 PF00568.23 GAK65992.1 - 5.8e-26 90.6 0.0 8.5e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 GAK65992.1 - 1.3e-09 38.2 0.1 2.6e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain DCP1 PF06058.13 GAK65992.1 - 0.0027 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH2 PF02205.20 GAK65992.1 - 0.0055 16.5 0.2 0.017 15.0 0.2 1.9 1 0 0 1 1 1 1 WH2 motif DIOX_N PF14226.6 GAK65993.1 - 6.2e-21 75.3 0.0 1e-20 74.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAK65993.1 - 1.6e-16 60.6 0.0 3.5e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.23 GAK65994.1 - 6e-13 48.5 0.1 1.2e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAK65994.1 - 3.3e-08 33.4 0.1 9.3e-08 31.9 0.1 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Xan_ur_permease PF00860.20 GAK65995.1 - 5.3e-59 199.9 37.1 7.8e-59 199.3 36.7 1.4 1 1 0 1 1 1 1 Permease family ATP1G1_PLM_MAT8 PF02038.16 GAK65995.1 - 0.035 13.5 0.3 0.32 10.5 0.3 2.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Ferric_reduct PF01794.19 GAK65996.1 - 1.4e-24 86.5 9.9 1.4e-24 86.5 9.9 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAK65996.1 - 2.3e-16 60.3 0.0 3.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAK65996.1 - 7.2e-13 48.6 0.0 1.6e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAK65996.1 - 8.1e-07 29.7 0.0 2.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FixQ PF05545.11 GAK65996.1 - 5.1 7.1 8.9 7.5 6.6 0.8 3.2 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Ctr PF04145.15 GAK65997.1 - 9.9e-39 133.3 1.9 1.7e-38 132.6 1.9 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.6 GAK65997.1 - 0.01 15.9 3.9 0.017 15.2 3.9 1.3 1 0 0 1 1 1 0 Putative sensor AA_permease PF00324.21 GAK65998.1 - 1.8e-118 396.2 43.6 2.2e-118 395.9 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK65998.1 - 1.2e-35 123.2 46.4 1.5e-35 122.9 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 GAK65998.1 - 0.49 10.9 5.2 5.4 7.5 0.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Alpha-amylase PF00128.24 GAK65999.1 - 1.9e-113 379.4 0.0 2.7e-113 379.0 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GAK65999.1 - 0.0059 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 GAK65999.1 - 0.008 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 GAK65999.1 - 0.019 15.1 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain RFX5_N PF18326.1 GAK65999.1 - 0.039 13.7 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 RFX5 N-terminal domain Biotin_carb_N PF00289.22 GAK65999.1 - 0.2 12.2 0.0 0.52 10.9 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain DUF543 PF04418.12 GAK66000.1 - 1.2e-29 102.1 0.1 3.9e-29 100.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4536 PF15055.6 GAK66000.1 - 0.00041 20.5 0.7 0.00041 20.5 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF883 PF05957.13 GAK66000.1 - 0.0011 19.5 3.4 0.16 12.5 3.7 2.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GAK66000.1 - 0.044 13.7 2.4 0.068 13.0 2.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.6 GAK66000.1 - 3.9 7.8 17.8 7.4 7.0 17.8 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein ATP-synt_B PF00430.18 GAK66000.1 - 5.3 7.1 12.1 11 6.1 12.1 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Peroxidase_2 PF01328.17 GAK66001.1 - 7.5e-43 147.2 0.0 1.3e-42 146.4 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 RNase_T PF00929.24 GAK66002.1 - 2.1e-07 31.7 0.2 4.8e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Exonuclease CHORD PF04968.12 GAK66002.1 - 0.052 14.3 0.9 0.16 12.7 0.9 1.8 1 0 0 1 1 1 0 CHORD DUF2180 PF09947.9 GAK66002.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) PINIT PF14324.6 GAK66003.1 - 3.7e-29 101.9 0.1 5.6e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 GAK66003.1 - 1.3e-21 76.1 7.5 2.2e-21 75.3 7.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GAK66003.1 - 8.2e-06 25.5 1.5 1.7e-05 24.5 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAK66003.1 - 0.85 9.5 4.8 1.9 8.4 4.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Whi5 PF08528.11 GAK66004.1 - 0.042 13.5 0.2 0.072 12.7 0.2 1.4 1 0 0 1 1 1 0 Whi5 like zf-H2C2_2 PF13465.6 GAK66005.1 - 1.8e-08 34.4 0.6 1.8e-08 34.4 0.6 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 GAK66005.1 - 1.4e-07 31.6 11.1 1.9e-06 28.0 0.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAK66005.1 - 2.7e-05 24.7 17.7 0.0024 18.4 1.6 4.5 2 2 3 5 5 5 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAK66005.1 - 0.00013 22.5 10.9 0.0056 17.4 0.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAK66005.1 - 0.0038 17.2 4.2 0.11 12.5 0.0 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 GAK66005.1 - 0.0096 16.3 1.4 5.2 7.6 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF812 PF05667.11 GAK66005.1 - 0.076 11.9 4.6 0.11 11.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) zf_ZIC PF18366.1 GAK66005.1 - 0.58 10.3 10.5 2.9 8.1 1.9 3.8 4 1 0 4 4 4 0 Zic proteins zinc finger domain DFP PF04127.15 GAK66006.1 - 3.1e-18 66.3 0.0 4.1e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein AA_permease PF00324.21 GAK66007.1 - 1.4e-116 389.9 34.3 1.8e-116 389.6 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK66007.1 - 6.4e-34 117.5 37.6 1.2e-33 116.6 37.6 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3435 PF11917.8 GAK66008.1 - 0.00059 18.9 0.0 0.0016 17.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DSPc PF00782.20 GAK66009.1 - 2.2e-19 69.6 0.3 6.9e-16 58.3 0.6 2.7 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAK66009.1 - 0.0031 17.1 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2514 PF10721.9 GAK66009.1 - 0.077 13.0 10.8 0.23 11.5 10.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RNB PF00773.19 GAK66011.1 - 4.7e-95 318.7 0.0 6.6e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 GAK66011.1 - 1.6e-22 79.3 0.2 3.1e-22 78.3 0.2 1.5 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 GAK66011.1 - 9.6e-20 70.8 0.0 2.5e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 GAK66011.1 - 1.6e-17 63.2 0.0 3.8e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 GAK66011.1 - 2e-09 37.8 0.4 8e-09 35.9 0.4 2.1 1 1 0 1 1 1 1 PIN domain CSD2 PF17876.1 GAK66011.1 - 1.8e-07 31.2 0.0 0.00019 21.5 0.0 3.2 3 0 0 3 3 3 2 Cold shock domain OB_RNB PF08206.11 GAK66011.1 - 0.01 15.5 0.0 0.04 13.6 0.1 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF572 PF04502.13 GAK66015.1 - 1.4e-50 172.8 0.9 1.6e-50 172.7 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1871 PF08958.10 GAK66015.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) GATA PF00320.27 GAK66017.1 - 1.5e-26 91.7 15.7 3.5e-14 52.1 3.9 2.4 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 GAK66017.1 - 1.3e-09 37.7 0.9 2.7e-09 36.7 0.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 GAK66017.1 - 6.6e-05 22.3 3.5 0.097 12.2 0.5 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 GAK66017.1 - 0.00026 21.0 0.7 1.1 9.5 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 GAK66017.1 - 0.012 15.5 3.5 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 GAK66017.1 - 0.092 13.1 0.8 4.6 7.7 0.0 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar Elf1 PF05129.13 GAK66017.1 - 0.11 12.6 0.2 6.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 GAK66017.1 - 0.13 12.3 4.5 1 9.5 0.4 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Auto_anti-p27 PF06677.12 GAK66017.1 - 0.54 10.5 6.2 2.9 8.1 0.8 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 GAK66017.1 - 0.75 9.9 8.1 9.5 6.3 7.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-RRN7 PF11781.8 GAK66017.1 - 0.87 9.3 5.3 0.48 10.2 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TRAPPC-Trs85 PF12739.7 GAK66018.1 - 2.2e-114 382.6 0.0 3.1e-114 382.1 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Foie-gras_1 PF11817.8 GAK66018.1 - 0.0095 15.6 1.3 0.018 14.6 1.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 DUF3078 PF11276.8 GAK66018.1 - 0.2 12.1 0.1 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3078) Glyco_hydro_47 PF01532.20 GAK66019.1 - 8.8e-150 499.6 0.0 1.5e-149 498.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 GAK66019.1 - 0.06 12.9 1.5 3.3 7.1 0.2 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Fungal_trans PF04082.18 GAK66020.1 - 9.7e-15 54.3 0.0 2.1e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK66020.1 - 2.3e-07 30.8 8.9 4.4e-07 29.9 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.17 GAK66022.1 - 6.6e-32 110.8 0.0 1.3e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAK66022.1 - 0.00071 19.3 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 SURF4 PF02077.15 GAK66024.1 - 1.8e-93 313.0 4.7 2e-93 312.8 4.7 1.0 1 0 0 1 1 1 1 SURF4 family DUF5562 PF17717.1 GAK66024.1 - 0.095 12.7 2.0 0.11 12.4 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5562) HR_lesion PF05514.11 GAK66024.1 - 0.81 9.9 9.8 0.37 11.0 2.6 2.8 3 1 0 3 3 3 0 HR-like lesion-inducing Mito_carr PF00153.27 GAK66025.1 - 1.3e-50 169.3 4.2 1.3e-17 63.5 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 GAK66026.1 - 2.1e-68 230.6 0.0 3.3e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66026.1 - 3.9e-49 167.3 0.0 6.7e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK66026.1 - 3.6e-05 22.7 0.6 0.00019 20.4 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAK66026.1 - 0.031 13.6 0.0 0.099 11.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 GAK66026.1 - 0.068 12.1 0.0 4.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain CCDC53 PF10152.9 GAK66026.1 - 8.7 6.7 17.1 9.8 6.6 3.9 3.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex COG2 PF06148.11 GAK66027.1 - 9.5e-15 54.9 6.5 6.3e-12 45.7 0.1 2.9 3 0 0 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 GAK66027.1 - 1.1e-07 32.3 0.1 1.8e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 GAK66027.1 - 0.03 14.4 0.1 0.077 13.1 0.1 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Zw10 PF06248.13 GAK66027.1 - 0.081 11.5 0.0 0.69 8.4 0.0 2.0 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Tombus_movement PF05318.12 GAK66027.1 - 0.19 12.6 1.8 0.35 11.7 0.5 2.2 2 0 0 2 2 2 0 Tombusvirus movement protein DUF4404 PF14357.6 GAK66027.1 - 0.33 11.6 2.3 1.2 9.9 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) adh_short PF00106.25 GAK66028.1 - 1.1e-27 96.8 0.2 5.4e-15 55.4 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK66028.1 - 9e-15 54.9 0.1 2.1e-08 34.0 0.3 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK66028.1 - 2.3e-12 47.2 0.7 1.4e-10 41.4 0.1 2.3 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 GAK66028.1 - 5.4e-05 22.6 0.0 8.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GAK66028.1 - 0.00047 19.7 0.1 0.00098 18.7 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAK66028.1 - 0.00077 19.4 0.9 0.0017 18.3 0.9 1.7 1 1 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 GAK66028.1 - 0.0017 18.9 0.2 0.0049 17.4 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 GAK66028.1 - 0.004 17.4 0.5 0.0077 16.5 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAK66028.1 - 0.0059 16.5 0.2 0.01 15.7 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAK66028.1 - 0.017 14.5 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 GAK66028.1 - 0.017 15.0 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 GAK66028.1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Helicase_RecD PF05127.14 GAK66028.1 - 0.039 13.8 0.3 0.067 13.0 0.3 1.3 1 0 0 1 1 1 0 Helicase NAD_binding_2 PF03446.15 GAK66028.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 GAK66028.1 - 0.061 13.3 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase La PF05383.17 GAK66029.1 - 1.6e-22 79.3 0.0 1.2e-21 76.5 0.0 2.4 3 0 0 3 3 3 1 La domain RRM_1 PF00076.22 GAK66029.1 - 1.1e-07 31.5 0.2 4e-07 29.8 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAK66029.1 - 4.6e-06 26.6 0.3 0.00065 19.7 0.1 2.7 2 0 0 2 2 2 2 RNA binding motif Pro_isomerase PF00160.21 GAK66031.1 - 3.5e-48 163.8 0.1 4e-48 163.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_5 PF13857.6 GAK66032.1 - 8.9e-18 64.1 2.5 2.2e-10 40.6 0.1 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK66032.1 - 1.4e-17 64.1 0.2 4.5e-12 46.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK66032.1 - 3.6e-17 62.5 0.8 9.7e-13 48.4 0.4 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAK66032.1 - 1.1e-13 51.0 3.8 0.00024 21.4 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 GAK66032.1 - 1.8e-12 46.2 4.2 0.0015 18.8 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat IDO PF01231.18 GAK66033.1 - 1.8e-35 122.6 0.0 2.7e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Chorismate_bind PF00425.18 GAK66034.1 - 2.3e-76 256.7 0.0 3.6e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 GAK66034.1 - 1.8e-31 109.4 0.0 3e-21 76.1 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAK66034.1 - 2.3e-14 53.8 0.0 6.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAK66034.1 - 1.3e-07 31.6 0.0 3.7e-05 23.6 0.0 2.5 2 1 0 2 2 2 2 Peptidase C26 GGDEF_2 PF17853.1 GAK66034.1 - 0.11 12.8 0.5 1.3 9.3 0.1 2.9 2 0 0 2 2 2 0 GGDEF-like domain ERAP1_C PF11838.8 GAK66035.1 - 0.0052 16.4 2.2 0.17 11.4 0.1 3.2 3 0 0 3 3 3 1 ERAP1-like C-terminal domain TPR_14 PF13428.6 GAK66035.1 - 8.3 7.5 12.5 13 6.9 0.5 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Creatinase_N_2 PF16189.5 GAK66037.1 - 8.9e-47 159.2 0.0 7.9e-45 152.8 0.0 2.6 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GAK66037.1 - 2.6e-44 151.4 0.0 4.1e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 GAK66037.1 - 1.1e-22 79.8 0.0 2.5e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAK66037.1 - 6.1e-21 75.5 0.0 1.9e-18 67.4 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain AdoHcyase PF05221.17 GAK66038.1 - 1.8e-133 444.3 0.0 2.4e-74 250.2 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GAK66038.1 - 1.5e-84 282.0 3.3 2.3e-84 281.4 3.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAK66038.1 - 3.2e-10 39.6 0.0 6.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAK66038.1 - 0.00047 19.8 0.2 0.00074 19.1 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 GAK66038.1 - 0.0031 17.8 0.1 0.0066 16.7 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 GAK66038.1 - 0.054 13.9 0.1 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 GAK66038.1 - 0.068 12.5 0.6 0.31 10.3 0.6 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 GAK66038.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Septin PF00735.18 GAK66039.1 - 8.2e-123 409.2 0.7 1.3e-122 408.4 0.7 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAK66039.1 - 7.8e-09 35.6 0.2 2.2e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK66039.1 - 8.4e-06 25.8 3.8 4.2e-05 23.5 0.1 2.8 3 1 0 3 3 2 1 RsgA GTPase Dynamin_N PF00350.23 GAK66039.1 - 7.8e-05 22.8 2.8 0.13 12.3 0.0 3.2 2 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 GAK66039.1 - 0.00023 20.8 3.0 0.0024 17.4 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 GAK66039.1 - 0.0004 20.0 1.4 0.0055 16.3 0.0 2.7 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.6 GAK66039.1 - 0.0022 18.3 0.7 0.011 16.0 0.0 2.5 3 2 0 3 3 3 1 AAA domain AIG1 PF04548.16 GAK66039.1 - 0.0028 17.0 0.8 0.0062 15.9 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 GAK66039.1 - 0.005 17.4 7.8 0.019 15.5 1.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 GAK66039.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK66039.1 - 0.017 15.5 0.1 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 GAK66039.1 - 0.024 14.8 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Exonuc_VII_L PF02601.15 GAK66039.1 - 0.075 12.6 5.5 0.14 11.7 5.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.6 GAK66039.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GAK66039.1 - 0.18 11.6 0.3 15 5.3 0.0 3.2 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 GAK66039.1 - 0.26 11.1 4.5 0.45 10.2 2.5 2.1 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 GAK66039.1 - 0.45 10.9 9.7 0.95 9.8 9.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP_bind_1 PF03029.17 GAK66039.1 - 2.1 8.1 4.5 27 4.4 0.0 3.2 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein Atg14 PF10186.9 GAK66039.1 - 2.2 7.3 7.3 3.8 6.5 7.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 GAK66039.1 - 8 7.0 8.0 3.2e+02 1.9 7.6 3.2 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tht1 PF04163.12 GAK66040.1 - 1.9e-07 30.3 0.1 2.6e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Exonuc_VII_L PF02601.15 GAK66040.1 - 0.065 12.8 8.5 0.097 12.2 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit 7TMR-HDED PF07697.11 GAK66040.1 - 0.31 11.1 4.1 0.46 10.6 4.1 1.3 1 0 0 1 1 1 0 7TM-HD extracellular MRG PF05712.13 GAK66041.1 - 2.5e-60 203.2 0.0 3.4e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 GAK66041.1 - 2e-10 40.4 0.1 5.7e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GAK66041.1 - 0.03 14.3 1.5 0.087 12.8 1.5 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AMP-binding PF00501.28 GAK66042.1 - 1.5e-89 300.5 0.0 2e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK66042.1 - 0.0016 19.4 0.1 0.0044 18.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sec63 PF02889.16 GAK66043.1 - 1.5e-153 509.3 0.1 7.9e-82 274.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAK66043.1 - 3.1e-47 160.6 0.0 2.5e-25 89.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GAK66043.1 - 2.3e-39 134.0 0.3 6.3e-39 132.6 0.3 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 GAK66043.1 - 4.9e-22 78.7 0.0 7.4e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAK66043.1 - 8.2e-13 48.7 0.0 7.8e-07 29.4 0.0 3.9 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAK66043.1 - 6.3e-07 29.3 0.0 0.0019 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAK66043.1 - 4.4e-06 26.4 0.2 0.012 15.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAK66043.1 - 1.9e-05 25.0 0.1 0.2 11.9 0.1 3.5 3 1 0 3 3 3 2 AAA domain PhoH PF02562.16 GAK66043.1 - 0.022 14.2 0.0 0.36 10.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PHD PF00628.29 GAK66044.1 - 8.9e-07 28.7 14.2 1.5e-06 28.0 14.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAK66044.1 - 0.00061 19.3 6.0 0.0011 18.4 6.0 1.4 1 0 0 1 1 1 1 PHD-finger Stc1 PF12898.7 GAK66044.1 - 0.43 11.1 4.5 1.2 9.7 4.5 1.8 1 0 0 1 1 1 0 Stc1 domain RNA_pol_3_Rpc31 PF11705.8 GAK66045.1 - 1.2e-05 25.7 6.9 2.1e-05 24.9 6.9 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cnd1 PF12717.7 GAK66045.1 - 7.9e-05 22.8 8.8 0.11 12.5 0.1 5.9 4 3 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Pox_Ag35 PF03286.14 GAK66045.1 - 0.00043 20.1 6.3 0.00088 19.1 6.3 1.5 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Ecm29 PF13001.7 GAK66045.1 - 0.00077 18.3 0.8 0.042 12.5 0.0 3.4 4 0 0 4 4 4 1 Proteasome stabiliser Anticodon_1 PF08264.13 GAK66045.1 - 0.013 15.4 0.1 0.055 13.4 0.1 2.1 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA HEAT_2 PF13646.6 GAK66045.1 - 0.044 14.2 20.9 0.067 13.6 0.3 6.8 5 2 1 6 6 6 0 HEAT repeats HEAT PF02985.22 GAK66045.1 - 0.055 13.7 11.9 20 5.8 0.5 6.1 6 0 0 6 6 4 0 HEAT repeat UNC45-central PF11701.8 GAK66045.1 - 0.25 11.3 2.3 12 5.9 0.3 3.7 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central NOA36 PF06524.12 GAK66045.1 - 0.31 10.3 15.4 0.53 9.6 15.4 1.3 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 GAK66045.1 - 0.46 10.3 7.8 0.039 13.8 2.3 2.0 3 0 0 3 3 3 0 Myc amino-terminal region PBP1_TM PF14812.6 GAK66045.1 - 1.7 9.1 16.8 5.5 7.4 16.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYDLN_acid PF09538.10 GAK66045.1 - 4 8.2 17.7 14 6.5 17.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4746 PF15928.5 GAK66045.1 - 4.1 6.7 11.3 0.59 9.5 7.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Acyl-CoA_dh_2 PF08028.11 GAK66045.1 - 6.7 7.0 11.7 16 5.7 3.5 3.7 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain TLP-20 PF06088.11 GAK66045.1 - 7.7 6.4 8.2 1.7 8.5 4.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PPP4R2 PF09184.11 GAK66045.1 - 8.2 5.9 17.6 16 5.0 17.6 1.4 1 0 0 1 1 1 0 PPP4R2 zf-MYND PF01753.18 GAK66046.1 - 1.4e-10 41.1 10.9 1.4e-10 41.1 10.9 3.3 3 1 1 4 4 4 1 MYND finger SET PF00856.28 GAK66046.1 - 5.6e-09 36.6 0.0 1.8e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-Mss51 PF13824.6 GAK66046.1 - 0.018 15.1 8.5 0.6 10.3 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 NOA36 PF06524.12 GAK66047.1 - 9 5.5 29.3 1.7 7.9 9.3 3.1 3 0 0 3 3 3 0 NOA36 protein Aminotran_1_2 PF00155.21 GAK66048.1 - 1.8e-35 122.8 0.0 4e-35 121.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAK66048.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Myotoxins PF00819.17 GAK66048.1 - 0.16 12.3 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 Myotoxin, crotamine CHCH PF06747.13 GAK66049.1 - 6.8e-09 35.6 3.4 9.9e-09 35.1 3.4 1.3 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 GAK66049.1 - 0.0047 16.6 1.4 0.0059 16.3 1.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 GAK66049.1 - 0.01 15.8 3.6 0.016 15.2 3.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 GAK66049.1 - 0.014 15.7 4.0 0.044 14.1 4.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GAK66049.1 - 0.1 12.6 3.8 0.77 9.8 3.9 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 GAK66049.1 - 0.13 12.6 5.6 1.3 9.4 1.0 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 GAK66049.1 - 0.15 12.3 2.7 0.68 10.2 0.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Actin PF00022.19 GAK66050.1 - 3.6e-35 121.4 0.0 9.9e-35 119.9 0.0 1.7 1 1 0 1 1 1 1 Actin CN_hydrolase PF00795.22 GAK66057.1 - 2.6e-14 53.2 0.0 3.8e-11 42.8 0.0 3.6 3 1 0 3 3 3 2 Carbon-nitrogen hydrolase BolA PF01722.18 GAK66058.1 - 1.8e-18 66.6 0.1 3e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 BolA-like protein Adeno_Penton_B PF01686.17 GAK66058.1 - 0.032 12.7 0.0 0.041 12.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein UvrD-helicase PF00580.21 GAK66059.1 - 1.6e-14 54.2 0.0 8e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 GAK66059.1 - 1.1e-13 51.3 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GAK66059.1 - 3.9e-12 46.7 0.0 9e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 GAK66059.1 - 6.6e-11 41.9 1.1 4.6e-10 39.2 1.1 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 GAK66059.1 - 2.1e-08 34.2 0.4 0.11 12.2 0.0 3.6 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 GAK66059.1 - 2.2e-06 27.5 4.0 0.0091 15.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 GAK66059.1 - 0.00033 20.9 0.0 0.66 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 GAK66059.1 - 0.0016 17.9 0.0 0.084 12.3 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_12 PF13087.6 GAK66059.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.23 GAK66061.1 - 2.5e-45 153.3 0.5 1.7e-43 147.4 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAK66061.1 - 2.8e-33 114.5 0.2 5.9e-33 113.5 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain JAB PF01398.21 GAK66062.1 - 2e-30 105.2 0.8 2.7e-30 104.8 0.1 1.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 GAK66062.1 - 2.7e-20 73.1 0.5 5.1e-20 72.2 0.5 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 GAK66062.1 - 3.3e-05 23.6 0.0 7.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 GAK66062.1 - 0.054 13.5 0.4 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DSPc PF00782.20 GAK66063.1 - 0.00025 20.8 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAK66063.1 - 0.00035 20.7 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAK66063.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAK66063.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Aldedh PF00171.22 GAK66065.1 - 5.7e-119 397.6 0.1 6.8e-119 397.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 GAK66066.1 - 7.6e-21 74.0 3.2 0.00078 20.2 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66066.1 - 1.7e-09 37.8 0.1 8.5e-07 29.2 0.0 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK66066.1 - 0.00074 18.6 0.1 0.062 12.2 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gcd10p PF04189.13 GAK66066.1 - 0.042 12.9 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Gcd10p family MMS1_N PF10433.9 GAK66066.1 - 0.061 12.0 0.0 0.2 10.2 0.0 1.7 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pyr_redox_2 PF07992.14 GAK66067.1 - 2.6e-52 177.9 0.1 3.3e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK66067.1 - 2.9e-18 66.2 0.7 1.7e-15 57.3 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK66067.1 - 4.9e-18 65.4 0.3 1.6e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK66067.1 - 3.5e-05 23.2 0.1 0.0003 20.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAK66067.1 - 4.8e-05 23.5 0.1 0.0027 17.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAK66067.1 - 5.6e-05 22.7 0.2 0.018 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK66067.1 - 0.00028 20.1 0.6 0.016 14.3 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAK66067.1 - 0.00056 19.6 0.1 0.0038 16.8 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GAK66067.1 - 0.00084 18.5 2.5 0.014 14.5 0.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.6 GAK66067.1 - 0.0036 16.5 0.1 0.045 12.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 GAK66067.1 - 0.0044 17.4 0.2 0.18 12.3 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.14 GAK66067.1 - 0.0085 14.8 0.4 0.027 13.2 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 GAK66067.1 - 0.014 14.3 0.1 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 GAK66067.1 - 0.02 14.2 1.7 0.071 12.3 0.1 2.4 2 1 1 3 3 3 0 FAD binding domain DEAD PF00270.29 GAK66068.1 - 3.9e-33 114.7 1.4 4.2e-33 114.6 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK66068.1 - 3.7e-29 101.3 0.2 9.5e-29 100.0 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.14 GAK66068.1 - 0.0001 22.3 0.1 0.00026 21.0 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 GAK66068.1 - 0.00047 19.9 0.1 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF4844 PF16133.5 GAK66068.1 - 0.1 13.1 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) CDC27 PF09507.10 GAK66069.1 - 1.2e-88 298.4 59.6 3.1e-87 293.7 59.6 2.2 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF5572 PF17733.1 GAK66070.1 - 1.6e-19 69.5 1.9 1.6e-19 69.5 1.9 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5572) DUF3323 PF11796.8 GAK66070.1 - 0.047 13.6 0.0 1.8 8.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Gcd10p PF04189.13 GAK66071.1 - 1e-77 261.2 0.0 2.5e-77 260.0 0.0 1.6 2 0 0 2 2 2 1 Gcd10p family PDDEXK_2 PF12784.7 GAK66071.1 - 0.093 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase DUF2052 PF09747.9 GAK66072.1 - 0.056 13.6 9.2 0.071 13.2 9.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 GAK66072.1 - 0.11 11.4 2.7 0.14 11.2 2.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 GAK66072.1 - 0.27 10.7 6.0 0.3 10.6 6.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.15 GAK66072.1 - 2.2 7.0 7.6 2.5 6.8 7.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GAK66072.1 - 7.2 5.3 7.6 8.1 5.1 7.6 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GAK66072.1 - 8.4 4.5 12.3 9.7 4.3 12.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Ssu72 PF04722.13 GAK66073.1 - 1.1e-80 269.8 0.0 1.2e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.21 GAK66073.1 - 0.19 12.1 0.4 0.63 10.4 0.2 1.9 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Ras PF00071.22 GAK66074.1 - 1e-53 181.3 0.0 1.2e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK66074.1 - 2.8e-21 75.9 0.0 1.2e-20 73.9 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK66074.1 - 4.9e-07 29.4 0.0 9.4e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 GAK66074.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 GAK66074.1 - 0.2 11.4 0.3 2.2 8.0 0.3 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 GAK66074.1 - 0.23 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MerR-DNA-bind PF09278.11 GAK66075.1 - 0.029 14.9 2.3 3.9 8.1 0.1 3.0 2 0 0 2 2 2 0 MerR, DNA binding TPR_2 PF07719.17 GAK66075.1 - 0.25 11.5 1.2 14 6.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 GAK66076.1 - 1e-46 158.9 0.0 1.9e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK66076.1 - 1.7e-27 96.0 0.0 5.9e-26 91.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK66076.1 - 8.2e-06 25.9 0.0 3.6e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 GAK66076.1 - 0.02 15.4 0.2 0.065 13.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) UPF0240 PF06784.11 GAK66076.1 - 1.5 8.9 6.9 3.3 7.7 6.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) CMS1 PF14617.6 GAK66076.1 - 3 7.1 6.5 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Acyl-CoA_dh_1 PF00441.24 GAK66077.1 - 2.5e-32 112.2 1.3 3.5e-32 111.7 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAK66077.1 - 1.7e-17 63.4 0.1 3e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAK66077.1 - 4e-12 46.8 0.0 2.1e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAK66077.1 - 3.8e-10 40.2 0.7 5.7e-10 39.6 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_transf_8 PF01501.20 GAK66078.1 - 2.1e-05 24.2 0.4 0.0002 21.0 0.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 SUZ PF12752.7 GAK66079.1 - 1.4e-15 57.8 5.0 1.4e-15 57.8 5.0 5.3 5 2 0 5 5 5 1 SUZ domain R3H PF01424.22 GAK66079.1 - 1.1e-08 34.9 0.5 1.1e-08 34.9 0.5 1.7 2 0 0 2 2 2 1 R3H domain UCH PF00443.29 GAK66080.1 - 6.3e-41 140.6 0.0 1e-40 139.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK66080.1 - 4.4e-07 29.8 0.0 0.0033 17.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase NAD_binding_1 PF00175.21 GAK66082.1 - 1.5e-26 93.2 0.0 4.8e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAK66082.1 - 8.6e-20 70.9 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAK66082.1 - 6.4e-05 23.1 0.0 0.00045 20.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ABC_tran PF00005.27 GAK66083.1 - 2.1e-46 157.8 0.1 1.6e-21 77.3 0.0 3.3 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAK66083.1 - 1.3e-25 89.2 4.6 1.3e-25 89.2 4.6 3.7 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 GAK66083.1 - 1.9e-17 64.0 0.0 0.00036 20.4 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAK66083.1 - 3.7e-11 42.9 0.2 0.0012 18.4 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK66083.1 - 1.5e-07 31.0 0.5 0.0077 15.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAK66083.1 - 3.2e-07 30.4 0.3 0.039 14.0 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 GAK66083.1 - 3.3e-06 27.4 0.6 0.15 12.3 0.1 4.0 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.6 GAK66083.1 - 5.3e-06 27.0 0.1 0.99 10.0 0.0 3.7 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAK66083.1 - 7.2e-06 26.0 0.1 0.084 12.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 GAK66083.1 - 1.1e-05 25.4 0.2 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 GAK66083.1 - 1.8e-05 25.2 2.4 0.24 11.8 0.0 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 GAK66083.1 - 0.00034 20.3 0.2 1.4 8.5 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_7 PF12775.7 GAK66083.1 - 0.00042 19.9 0.1 0.73 9.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 GAK66083.1 - 0.00049 19.9 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAK66083.1 - 0.00078 19.8 0.0 0.32 11.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 GAK66083.1 - 0.001 19.5 0.1 0.29 11.6 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 GAK66083.1 - 0.0026 17.6 6.7 0.94 9.1 0.0 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 GAK66083.1 - 0.0034 17.4 0.0 4.6 7.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 GAK66083.1 - 0.0051 15.8 0.1 1.4 7.8 0.0 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 GAK66083.1 - 0.01 16.0 0.0 5.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 GAK66083.1 - 0.012 15.9 8.1 0.64 10.2 0.3 3.4 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 GAK66083.1 - 0.013 14.7 0.2 3.2 6.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 GAK66083.1 - 0.027 14.6 4.5 0.13 12.3 0.0 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain cobW PF02492.19 GAK66083.1 - 0.04 13.5 0.0 7 6.2 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 GAK66083.1 - 0.049 13.6 0.0 6.9 6.5 0.0 2.7 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 GAK66083.1 - 0.055 13.2 0.0 7.9 6.2 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 GAK66083.1 - 0.079 13.5 0.0 0.079 13.5 0.0 4.7 4 1 0 5 5 4 0 AAA domain AAA_27 PF13514.6 GAK66083.1 - 0.084 12.5 3.3 0.6 9.7 0.0 3.1 3 1 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 GAK66083.1 - 0.11 12.5 2.9 1 9.4 0.0 3.3 4 0 0 4 4 4 0 Dynamin family ATP_bind_1 PF03029.17 GAK66083.1 - 0.13 12.0 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 GAK66083.1 - 0.29 11.3 13.2 0.46 10.6 0.0 3.8 4 1 0 4 4 3 0 AAA domain Pilt PF15453.6 GAK66083.1 - 0.95 8.8 6.2 0.093 12.1 1.8 1.5 2 0 0 2 2 1 0 Protein incorporated later into Tight Junctions AAA_5 PF07728.14 GAK66083.1 - 1.3 9.1 4.3 19 5.3 0.0 3.2 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) DUF4391 PF14335.6 GAK66083.1 - 5.6 6.6 10.7 2.5 7.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4391) Cyclase PF04199.13 GAK66084.1 - 1.5e-13 51.1 0.0 3.2e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 Putative cyclase LTXXQ PF07813.12 GAK66084.1 - 0.3 11.8 4.0 24 5.7 3.9 2.6 2 0 0 2 2 2 0 LTXXQ motif family protein Mur_ligase_M PF08245.12 GAK66085.1 - 1.4e-06 28.5 0.0 6.6e-05 23.0 0.0 3.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 GAK66085.1 - 0.05 13.9 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain R3H PF01424.22 GAK66086.1 - 1.4e-09 37.8 0.1 3.3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 GAK66086.1 - 4.2e-08 32.9 0.3 8.7e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMEM51 PF15345.6 GAK66086.1 - 0.86 9.4 4.2 0.63 9.8 0.2 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 NCBP3 PF10309.9 GAK66087.1 - 5.5e-14 51.7 0.0 8.9e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 MRP-L20 PF12824.7 GAK66087.1 - 0.026 14.7 1.0 0.026 14.7 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 DUF4238 PF14022.6 GAK66087.1 - 0.04 13.4 0.3 0.06 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) BTB PF00651.31 GAK66088.1 - 7.7e-10 39.0 0.3 0.00033 20.8 0.0 3.5 3 1 0 3 3 3 3 BTB/POZ domain SLX9 PF15341.6 GAK66088.1 - 0.019 15.4 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 MATH PF00917.26 GAK66088.1 - 0.068 13.3 0.6 0.24 11.5 0.3 2.0 1 1 1 2 2 2 0 MATH domain Striatin PF08232.12 GAK66089.1 - 8e-51 172.7 0.0 8e-51 172.7 0.0 3.3 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 GAK66089.1 - 2.3e-36 123.2 3.3 1.2e-06 29.1 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66089.1 - 5.7e-06 26.5 0.0 2.8 8.3 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAK66089.1 - 0.0031 16.3 0.0 4.6 5.9 0.0 3.3 3 0 0 3 3 3 2 Nup133 N terminal like PAN_3 PF08277.12 GAK66089.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 PAN-like domain NICE-1 PF15845.5 GAK66089.1 - 0.031 15.1 1.7 0.031 15.1 1.7 4.2 5 0 0 5 5 5 0 Cysteine-rich C-terminal 1 family Sulfate_transp PF00916.20 GAK66090.1 - 5.4e-59 199.8 18.0 8.5e-59 199.2 18.0 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 GAK66090.1 - 1e-12 48.0 0.0 2.3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 GAK66090.1 - 4.8e-08 32.6 0.0 9.5e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain HTH_Tnp_Tc3_2 PF01498.18 GAK66090.1 - 5.9 7.2 5.7 1.4 9.2 1.6 2.1 2 0 0 2 2 2 0 Transposase Med26 PF08711.11 GAK66091.1 - 9.2e-09 35.2 0.0 4.1e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF5560 PF17715.1 GAK66091.1 - 0.025 14.0 0.1 0.74 9.2 0.0 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5560) MTCP1 PF08991.10 GAK66092.1 - 1.3e-24 86.2 3.7 1.6e-24 85.9 3.7 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 GAK66092.1 - 0.6 10.3 5.3 0.97 9.6 5.3 1.4 1 0 0 1 1 1 0 CHCH domain Peptidase_S9 PF00326.21 GAK66095.1 - 0.0022 17.5 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 GAK66095.1 - 0.004 16.1 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK66095.1 - 0.019 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK66095.1 - 0.035 13.4 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 R3H PF01424.22 GAK66096.1 - 2.1e-15 56.4 0.0 3.7e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 R3H domain AFOR_N PF02730.15 GAK66096.1 - 0.031 14.2 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain zf-NF-X1 PF01422.17 GAK66096.1 - 2.1 8.5 33.3 0.35 11.0 11.4 2.8 2 0 0 2 2 2 0 NF-X1 type zinc finger HSP70 PF00012.20 GAK66097.1 - 3e-256 851.4 8.0 3.4e-256 851.2 8.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAK66097.1 - 5.5e-16 58.3 0.2 3.4e-14 52.4 0.1 2.4 2 0 0 2 2 2 1 MreB/Mbl protein PIN_8 PF18476.1 GAK66097.1 - 0.006 16.5 5.3 0.047 13.5 1.7 2.2 2 0 0 2 2 2 1 PIN like domain Hydantoinase_A PF01968.18 GAK66097.1 - 0.011 15.1 0.1 0.028 13.7 0.1 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 GAK66097.1 - 0.019 14.7 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAK66097.1 - 0.04 14.3 2.2 17 5.9 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA 7TMR-HDED PF07697.11 GAK66097.1 - 0.12 12.5 10.7 0.2 11.7 10.7 1.6 1 1 0 1 1 1 0 7TM-HD extracellular DUF4226 PF10774.9 GAK66097.1 - 0.7 10.2 7.2 1.7 8.9 0.1 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4226) Mcl1_mid PF12341.8 GAK66098.1 - 2.3e-83 279.9 0.0 2.1e-81 273.6 0.0 2.7 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 GAK66098.1 - 7.1e-13 48.8 5.1 0.00042 21.1 0.0 6.3 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66098.1 - 2.6e-10 40.5 0.0 1.7e-05 25.0 0.0 5.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 GAK66098.1 - 0.12 11.6 0.0 5.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SAGA-Tad1 PF12767.7 GAK66099.1 - 6.6e-45 153.7 0.0 1.2e-44 152.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit BRCT PF00533.26 GAK66101.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 GAK66101.1 - 0.075 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAK66101.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Pkinase PF00069.25 GAK66103.1 - 4.5e-42 144.2 0.1 5.1e-21 75.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66103.1 - 2.2e-10 40.3 0.2 6.8e-08 32.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 GAK66103.1 - 0.29 10.7 0.1 0.49 10.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1b PF00579.25 GAK66105.1 - 8.1e-21 74.6 0.0 5.3e-20 71.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3860 PF12976.7 GAK66105.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) LSM PF01423.22 GAK66106.1 - 5.5e-14 51.6 0.0 7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAK66106.1 - 0.001 19.2 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 GAK66106.1 - 0.097 12.8 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 RimP C-terminal SH3 domain TAF PF02969.17 GAK66107.1 - 6.3e-27 93.5 0.5 1.2e-26 92.7 0.5 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 GAK66107.1 - 3.5e-14 52.9 0.0 7.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 GAK66107.1 - 5.1e-05 23.6 0.5 0.00011 22.6 0.5 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAK66107.1 - 0.00096 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Tubulin PF00091.25 GAK66108.1 - 9.4e-70 234.8 0.0 1.3e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAK66108.1 - 2.4e-43 147.3 0.0 4.4e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAK66108.1 - 1.2e-06 28.8 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 GAK66108.1 - 0.0047 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DEAD_2 PF06733.15 GAK66108.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 Fibrillarin PF01269.17 GAK66110.1 - 5.3e-105 349.5 0.0 6.5e-105 349.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 GAK66110.1 - 6.8e-06 25.9 0.0 9.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 GAK66110.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAK66110.1 - 0.057 13.5 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 GAK66110.1 - 0.064 13.0 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Avl9 PF09794.9 GAK66111.1 - 7.4e-140 465.9 0.0 9.6e-140 465.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 GAK66111.1 - 6e-11 42.5 0.0 8.4e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 GAK66111.1 - 7.7e-10 38.7 0.1 3e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 GAK66111.1 - 1.9e-05 25.1 1.7 2.8e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Apt1 PF10351.9 GAK66112.1 - 1.7 7.4 8.0 1.9 7.3 8.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Thaumatin PF00314.17 GAK66113.1 - 0.00048 19.8 0.1 0.00092 18.9 0.1 1.6 1 1 0 1 1 1 1 Thaumatin family Cytomega_UL20A PF05984.12 GAK66113.1 - 0.6 10.4 2.4 0.74 10.2 0.2 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein CENP-H PF05837.12 GAK66115.1 - 6.2e-12 45.9 4.6 6.2e-12 45.9 4.6 2.5 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF5375 PF17345.2 GAK66115.1 - 0.037 13.9 0.2 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5375) TFIIA PF03153.13 GAK66115.1 - 0.57 10.1 9.7 0.74 9.7 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 GAK66116.1 - 2.6e-98 328.6 0.0 2.6e-98 328.6 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Ribosomal_L28 PF00830.19 GAK66116.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L28 family Ras PF00071.22 GAK66117.1 - 1.2e-31 109.6 0.0 1.9e-29 102.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAK66117.1 - 3.4e-27 95.1 0.0 6.3e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK66117.1 - 2.7e-07 30.2 0.0 5.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK66117.1 - 3.8e-05 23.7 0.0 8.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK66117.1 - 0.00021 20.9 0.0 0.0026 17.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAK66117.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAK66117.1 - 0.05 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Glucosamine_iso PF01182.20 GAK66118.1 - 2.5e-74 250.0 0.0 3.3e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Na_H_Exchanger PF00999.21 GAK66119.1 - 6.8e-66 222.6 36.1 6.8e-66 222.6 36.1 1.6 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family SpoVAB PF13782.6 GAK66119.1 - 0.063 13.6 0.3 0.063 13.6 0.3 3.4 4 1 0 4 4 4 0 Stage V sporulation protein AB DUF2574 PF10836.8 GAK66119.1 - 0.11 12.4 1.0 0.34 10.8 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Nic96 PF04097.14 GAK66120.1 - 3.5e-183 610.4 0.9 4.3e-183 610.1 0.9 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Cation_efflux PF01545.21 GAK66121.1 - 5.8e-20 71.9 6.1 7.6e-20 71.5 6.1 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAK66121.1 - 1.9e-09 37.5 0.0 4.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter tRNA-synt_2b PF00587.25 GAK66122.1 - 3.7e-39 134.5 0.0 6.3e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAK66122.1 - 1.1e-12 48.0 0.0 3e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Anticodon binding domain RNA12 PF10443.9 GAK66123.1 - 1.2e-145 485.7 0.9 1.5e-145 485.3 0.9 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 GAK66123.1 - 5.4e-06 26.1 0.0 4e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 GAK66123.1 - 0.00015 21.8 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAK66123.1 - 0.0059 17.0 1.0 0.036 14.4 1.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 GAK66123.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2487 PF10673.9 GAK66123.1 - 0.034 14.2 0.0 0.21 11.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2487) NB-ARC PF00931.22 GAK66123.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain JTB PF05439.12 GAK66125.1 - 0.00081 19.4 2.0 0.0019 18.2 2.0 1.7 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) Mito_carr PF00153.27 GAK66126.1 - 0.00087 19.2 0.4 0.0087 16.0 0.0 2.6 3 0 0 3 3 3 1 Mitochondrial carrier protein Clathrin PF00637.20 GAK66127.1 - 1.5e-12 47.6 0.2 0.00029 20.7 0.0 3.3 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 GAK66127.1 - 1.9e-09 37.4 6.7 3.4e-09 36.6 6.7 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 GAK66127.1 - 0.00066 19.5 7.2 0.0011 18.7 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK66127.1 - 0.011 15.7 6.2 0.018 15.0 6.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 GAK66127.1 - 0.073 13.4 4.3 0.16 12.3 4.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAK66127.1 - 0.12 12.8 6.3 0.22 11.9 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 GAK66127.1 - 0.49 10.5 3.7 0.97 9.5 3.7 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Cas_Cas02710 PF09670.10 GAK66129.1 - 0.056 12.2 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) RXLR PF16810.5 GAK66130.1 - 0.83 10.1 3.1 8.1 6.9 3.5 2.1 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity SOR_SNZ PF01680.17 GAK66132.1 - 7.1e-110 365.7 5.7 9.3e-110 365.3 5.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 GAK66132.1 - 3.6e-06 26.5 9.6 7.7e-06 25.4 0.2 2.9 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 GAK66132.1 - 0.0032 17.5 0.0 0.025 14.6 0.0 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 GAK66132.1 - 0.0072 15.5 0.3 0.099 11.8 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 GAK66132.1 - 0.015 14.5 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Dus PF01207.17 GAK66132.1 - 0.043 12.9 0.3 0.56 9.2 0.0 2.3 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) UCR_TM PF02921.14 GAK66133.1 - 1.9e-11 44.3 0.6 7e-11 42.4 0.6 2.0 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 GAK66133.1 - 3.1e-10 39.8 0.6 7.9e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Dynactin PF12455.8 GAK66134.1 - 1.9e-76 257.0 2.1 1.9e-76 257.0 2.1 3.7 5 0 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 GAK66134.1 - 4.6e-22 77.8 1.6 5.9e-22 77.5 0.7 1.7 2 0 0 2 2 2 1 CAP-Gly domain Nup54_57_C PF18570.1 GAK66134.1 - 5.5 6.7 5.5 16 5.2 0.0 3.8 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain Fcf1 PF04900.12 GAK66135.1 - 1.7e-27 95.7 0.9 3.3e-27 94.8 0.9 1.5 1 0 0 1 1 1 1 Fcf1 DUF4787 PF16029.5 GAK66135.1 - 0.041 14.0 0.2 0.13 12.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) YL1 PF05764.13 GAK66135.1 - 3.6 7.6 23.6 7.5 6.6 23.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Tocopherol_cycl PF14249.6 GAK66137.1 - 0.00011 21.4 0.1 0.00025 20.3 0.0 1.5 2 0 0 2 2 2 1 Tocopherol cyclase Glyco_hydro_5_C PF18564.1 GAK66138.1 - 2.8e-20 72.6 1.7 7e-20 71.4 1.7 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 GAK66138.1 - 6.5e-11 42.2 0.0 1.3e-05 24.8 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF974 PF06159.13 GAK66139.1 - 2.7e-66 223.9 0.0 3.9e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) IDO PF01231.18 GAK66140.1 - 2.4e-146 487.9 0.0 3.1e-146 487.6 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ACPS PF01648.20 GAK66140.1 - 8.4e-11 42.0 0.0 3.5e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Astro_capsid_p2 PF16580.5 GAK66140.1 - 0.057 12.8 1.0 0.17 11.3 0.6 1.8 2 0 0 2 2 2 0 C-terminal tail of astrovirus capsid projection or spike Ras PF00071.22 GAK66141.1 - 1.3e-65 220.0 1.1 1.5e-65 219.7 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK66141.1 - 3e-36 124.3 0.1 5.1e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK66141.1 - 6.7e-18 64.8 0.2 8.6e-18 64.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAK66141.1 - 2.4e-06 27.5 1.0 0.034 14.0 0.2 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAK66141.1 - 6.1e-06 25.9 0.3 1.6e-05 24.5 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAK66141.1 - 2.8e-05 23.6 0.1 3.4e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK66141.1 - 4e-05 23.7 0.1 6.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAK66141.1 - 4.8e-05 22.9 0.0 6.8e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 GAK66141.1 - 0.0045 17.4 0.1 0.82 10.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 GAK66141.1 - 0.0076 15.8 0.1 0.066 12.7 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAK66141.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 GAK66141.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3873 PF12989.7 GAK66141.1 - 0.027 14.8 0.1 0.052 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) ABC_tran PF00005.27 GAK66141.1 - 0.038 14.5 0.4 0.11 13.1 0.4 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 GAK66141.1 - 0.04 14.2 0.0 0.073 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAK66141.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 GAK66141.1 - 0.053 12.9 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 GAK66141.1 - 0.067 12.5 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 GAK66141.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 GAK66141.1 - 0.089 12.5 0.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Nse4_C PF08743.10 GAK66142.1 - 4.5e-25 87.7 0.1 1.1e-24 86.4 0.0 1.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 GAK66142.1 - 2.5e-14 53.1 1.2 2.5e-14 53.1 1.2 2.2 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE SRR1 PF07985.12 GAK66143.1 - 8.5e-17 61.0 1.2 3e-16 59.2 1.2 1.9 1 1 0 1 1 1 1 SRR1 Rrn6 PF10214.9 GAK66143.1 - 0.1 11.1 7.5 0.12 10.9 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RNA_pol_Rpb5_C PF01191.19 GAK66144.1 - 6.7e-32 109.2 0.4 1.6e-31 108.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain Erf4 PF10256.9 GAK66144.1 - 1.1e-31 109.4 0.0 2.1e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_N PF03871.14 GAK66144.1 - 7.4e-28 97.0 0.4 1.3e-27 96.2 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 GAK66144.1 - 9.4e-05 22.4 0.0 0.00052 20.0 0.0 2.2 3 1 0 3 3 3 1 Restriction endonuclease KH_1 PF00013.29 GAK66145.1 - 2.9e-35 119.9 0.6 4.2e-08 32.9 0.0 6.9 7 0 0 7 7 7 5 KH domain ArsA_ATPase PF02374.15 GAK66146.1 - 8.4e-112 373.3 0.3 9.7e-112 373.1 0.3 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 GAK66146.1 - 9.1e-13 48.5 0.1 3.1e-12 46.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 GAK66146.1 - 2.5e-12 46.9 0.0 6.1e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GAK66146.1 - 1.6e-05 24.5 4.7 0.00046 19.7 1.5 2.8 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 GAK66146.1 - 1.8e-05 24.4 0.0 5.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 GAK66146.1 - 4.7e-05 23.0 0.1 0.00014 21.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 GAK66146.1 - 4.9e-05 23.1 0.2 0.00062 19.5 0.1 2.4 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.16 GAK66146.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein YabA PF06156.13 GAK66146.1 - 0.037 14.7 1.0 0.12 13.1 1.0 1.9 1 0 0 1 1 1 0 Initiation control protein YabA AAA_24 PF13479.6 GAK66146.1 - 0.052 13.3 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAK66146.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 GAK66146.1 - 0.082 12.5 1.3 1.3 8.5 1.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAK66146.1 - 0.089 13.3 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain BPL_N PF09825.9 GAK66147.1 - 1.3e-110 370.0 0.0 1.9e-110 369.5 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal RTC PF01137.21 GAK66147.1 - 2.6e-48 164.2 0.0 3.8e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GAK66147.1 - 6.3e-33 113.4 0.0 1.4e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain BPL_LplA_LipB PF03099.19 GAK66147.1 - 2.4e-17 63.1 0.0 5.2e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 GAK66147.1 - 0.11 12.4 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Ribonuc_2-5A PF06479.12 GAK66148.1 - 2.4e-44 150.6 0.1 4.7e-44 149.6 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 GAK66148.1 - 2.6e-38 131.9 0.0 1.6e-37 129.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66148.1 - 6.3e-19 68.3 0.0 2.8e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 GAK66148.1 - 1.2e-05 25.0 0.3 1.4e+02 1.9 0.0 3.0 2 1 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 GAK66148.1 - 3.5e-05 23.5 0.0 0.0003 20.6 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat Pkinase_fungal PF17667.1 GAK66148.1 - 0.00016 20.6 0.0 0.00016 20.6 0.0 2.8 3 1 0 3 3 2 1 Fungal protein kinase Kdo PF06293.14 GAK66148.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UIM PF02809.20 GAK66148.1 - 0.041 13.8 1.5 0.15 12.0 1.5 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif APH PF01636.23 GAK66148.1 - 0.052 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.6 GAK66148.1 - 0.16 12.5 1.2 9.8 6.8 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain YrbL-PhoP_reg PF10707.9 GAK66148.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TPR_14 PF13428.6 GAK66149.1 - 7.1e-10 38.9 28.4 1.5 9.9 0.0 13.5 11 3 4 15 15 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK66149.1 - 5.5e-07 30.0 4.8 0.55 10.8 1.8 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 GAK66149.1 - 4.3e-06 26.1 6.2 0.0015 17.8 0.0 4.8 3 1 1 4 4 4 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 GAK66149.1 - 0.00038 20.4 7.1 0.025 14.6 0.3 6.1 6 1 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 GAK66149.1 - 0.0012 18.9 9.1 21 5.6 0.1 7.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Suf PF05843.14 GAK66149.1 - 0.0042 17.1 14.4 0.31 11.0 1.7 6.1 3 2 1 5 5 5 2 Suppressor of forked protein (Suf) MIT PF04212.18 GAK66149.1 - 0.014 15.4 1.1 0.23 11.6 0.2 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 GAK66149.1 - 0.018 15.1 20.9 11 6.5 0.0 8.9 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAK66149.1 - 0.03 14.6 10.1 20 5.6 0.1 6.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK66149.1 - 4.2 8.2 15.6 72 4.3 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Zn_clus PF00172.18 GAK66150.1 - 4.4e-08 33.1 6.8 4.4e-08 33.1 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.18 GAK66151.1 - 2.5e-47 161.5 0.0 4.4e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain PPL5 PF18168.1 GAK66151.1 - 1.8 7.8 9.5 0.22 10.8 4.8 1.8 1 1 1 2 2 2 0 Prim-pol family 5 CybS PF05328.12 GAK66152.1 - 4.5e-42 142.9 0.0 5.6e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Ribosomal_L3 PF00297.22 GAK66153.1 - 8e-188 623.9 10.3 9.1e-188 623.8 10.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Oxidored_molyb PF00174.19 GAK66154.1 - 3.6e-57 192.7 0.0 7.1e-57 191.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAK66154.1 - 3.8e-45 153.3 0.1 8.1e-45 152.2 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 GAK66154.1 - 3.1e-30 105.0 0.0 7.1e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAK66154.1 - 1e-23 83.6 0.0 3e-23 82.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 GAK66154.1 - 1.4e-20 73.2 0.1 2.7e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GAK66154.1 - 0.018 15.2 0.0 0.078 13.1 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 GAK66155.1 - 2.3e-40 138.7 0.0 4.1e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 GAK66155.1 - 1e-19 70.6 0.0 1.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 GAK66155.1 - 2.6e-13 50.3 1.3 8.9e-13 48.6 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 GAK66155.1 - 7.8e-13 48.6 7.7 2.7e-10 40.4 3.6 3.0 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 GAK66155.1 - 2.8e-12 46.3 0.0 6.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.6 GAK66155.1 - 3.4e-12 46.2 0.0 9.3e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 GAK66155.1 - 5.3e-10 39.1 0.2 1.4e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.6 GAK66155.1 - 0.0001 22.4 0.3 3 7.8 0.0 3.5 2 1 1 3 3 3 2 FAD-NAD(P)-binding Rubredoxin_C PF18267.1 GAK66155.1 - 0.00068 19.5 1.2 1.6 8.7 0.1 2.8 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 GAK66155.1 - 0.02 14.2 0.0 1.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK66155.1 - 0.076 12.1 2.7 0.27 10.3 0.2 2.6 1 1 1 2 2 2 0 FAD binding domain TrkA_N PF02254.18 GAK66155.1 - 0.21 11.9 1.0 5.8 7.2 0.1 3.0 3 0 0 3 3 3 0 TrkA-N domain MFS_1 PF07690.16 GAK66156.1 - 2.5e-29 102.3 50.9 3e-28 98.8 28.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily GATase_2 PF00310.21 GAK66158.1 - 1.9e-175 583.6 0.0 2.4e-175 583.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GAK66158.1 - 6.2e-156 519.2 0.1 1.3e-155 518.1 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GAK66158.1 - 6e-116 386.8 0.0 1.2e-113 379.2 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAK66158.1 - 1.1e-85 286.0 1.3 1.8e-85 285.4 1.3 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GAK66158.1 - 2.3e-22 79.6 0.1 3.8e-21 75.6 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GAK66158.1 - 6.6e-21 74.2 0.1 1.3e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 GAK66158.1 - 1.7e-09 37.8 0.2 9.5e-09 35.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAK66158.1 - 4.6e-09 36.7 0.7 3.2e-05 24.4 0.1 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK66158.1 - 1.3e-06 27.4 2.1 7.3e-06 24.9 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 GAK66158.1 - 3.6e-06 26.3 0.8 0.014 14.5 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAK66158.1 - 3.8e-06 26.4 1.0 0.024 13.9 0.1 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAK66158.1 - 6.1e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAK66158.1 - 6.6e-06 25.5 2.5 0.00024 20.3 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAK66158.1 - 1.1e-05 25.0 5.3 0.00038 19.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 GAK66158.1 - 0.00021 21.0 1.0 0.0034 17.0 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FMN_dh PF01070.18 GAK66158.1 - 0.00056 19.0 1.0 0.0036 16.4 0.9 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase AdoHcyase_NAD PF00670.21 GAK66158.1 - 0.0021 18.2 1.9 0.79 9.8 0.3 3.4 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 GAK66158.1 - 0.0034 17.8 0.1 1.7 9.1 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 GAK66158.1 - 0.0041 16.4 0.3 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAK66158.1 - 0.015 14.4 0.4 0.62 9.1 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GAK66158.1 - 0.027 13.8 0.4 7.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 GAK66158.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 GAK66158.1 - 0.069 11.6 0.2 1.5 7.2 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 GAK66158.1 - 0.077 12.2 1.9 0.14 11.3 0.2 2.0 2 0 0 2 2 2 0 Thi4 family GATase_6 PF13522.6 GAK66158.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain 2-Hacid_dh_C PF02826.19 GAK66158.1 - 0.13 11.6 0.0 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAK66158.1 - 0.14 11.8 1.0 0.83 9.2 0.1 2.5 3 0 0 3 3 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 GAK66158.1 - 0.18 11.7 0.2 0.41 10.5 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3558 PF12079.8 GAK66159.1 - 0.0091 16.0 0.9 0.013 15.5 0.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3558) Adenylsucc_synt PF00709.21 GAK66160.1 - 1.4e-175 584.2 0.0 1.6e-175 584.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DNA_primase_lrg PF04104.14 GAK66161.1 - 1e-88 297.2 0.0 1.6e-88 296.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Nucleoporin_N PF08801.11 GAK66162.1 - 6.2e-45 153.7 0.0 8.7e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 GAK66162.1 - 3.8e-32 111.8 2.6 5.5e-32 111.3 2.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal BC10 PF06726.12 GAK66162.1 - 0.062 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 E1_dh PF00676.20 GAK66163.1 - 9.7e-111 369.5 0.2 1.2e-110 369.2 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAK66163.1 - 0.0014 17.9 0.2 0.0024 17.1 0.2 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAK66163.1 - 0.0029 17.4 2.4 0.0029 17.4 2.4 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NADH_B2 PF14813.6 GAK66164.1 - 2.4e-05 24.0 0.8 3.2e-05 23.6 0.8 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SWIRM-assoc_2 PF16496.5 GAK66165.1 - 1.2e-31 110.1 0.1 1.2e-31 110.1 0.1 2.0 2 1 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 GAK66165.1 - 1.8e-31 108.3 0.0 5.6e-31 106.7 0.2 1.8 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAK66165.1 - 6e-28 96.6 10.7 6e-28 96.6 10.7 2.3 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GAK66165.1 - 1.7e-10 40.9 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 GAK66165.1 - 1.9e-09 37.2 4.2 3.5e-09 36.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 GAK66165.1 - 1.9e-07 31.2 0.0 6.3e-06 26.4 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAK66165.1 - 0.013 15.4 0.2 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 Myb DNA-binding like DUF2112 PF09885.9 GAK66165.1 - 0.2 11.7 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) Macoilin PF09726.9 GAK66165.1 - 2.6 6.5 10.0 1.8 7.0 2.5 2.2 2 0 0 2 2 2 0 Macoilin family PhoD PF09423.10 GAK66166.1 - 1.9e-36 125.8 1.7 3.7e-36 124.9 0.5 2.0 2 1 0 2 2 2 1 PhoD-like phosphatase His_biosynth PF00977.21 GAK66167.1 - 2.3e-41 141.8 0.6 5.3e-25 88.2 0.4 2.9 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 GAK66167.1 - 3.9e-16 59.4 0.0 7.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 GAK66167.1 - 5.1e-07 29.7 0.0 1.7e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAK66167.1 - 1.7e-06 27.8 0.0 3.9e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain PBP PF01161.20 GAK66167.1 - 0.081 13.2 0.1 0.26 11.6 0.1 1.8 2 0 0 2 2 2 0 Phosphatidylethanolamine-binding protein Peptidase_C26 PF07722.13 GAK66167.1 - 0.1 12.3 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Asp PF00026.23 GAK66169.1 - 5.2e-40 137.8 0.0 2.6e-39 135.5 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK66169.1 - 4.5e-13 49.8 2.9 4.9e-11 43.2 0.9 2.8 3 1 0 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAK66169.1 - 4.4e-06 27.2 0.0 0.027 15.1 0.0 3.7 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAK66169.1 - 0.036 14.6 0.0 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.23 GAK66170.1 - 2.6e-49 168.3 12.1 5.1e-27 95.2 1.6 3.6 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 GAK66170.1 - 1.5e-44 151.9 0.0 1.5e-25 90.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAK66170.1 - 1.5e-09 37.6 0.4 9.6e-05 21.9 0.0 4.0 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK66170.1 - 2.4e-05 24.0 0.1 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK66170.1 - 4.7e-05 23.8 1.5 0.08 13.3 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAK66170.1 - 7.4e-05 23.0 0.5 0.94 9.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 GAK66170.1 - 0.00036 20.2 0.0 0.071 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAK66170.1 - 0.00046 20.0 0.1 0.02 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAK66170.1 - 0.00072 19.4 0.5 10 5.9 0.1 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 GAK66170.1 - 0.001 18.2 0.0 0.14 11.1 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 GAK66170.1 - 0.0066 16.1 2.3 0.022 14.3 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 GAK66170.1 - 0.0088 16.1 0.1 1.6 8.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAK66170.1 - 0.0096 16.4 4.4 1.2 9.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 GAK66170.1 - 0.01 15.8 0.3 0.95 9.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.29 GAK66170.1 - 0.018 14.8 0.1 6.9 6.4 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_30 PF13604.6 GAK66170.1 - 0.032 13.9 0.6 0.86 9.3 0.0 3.0 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 GAK66170.1 - 0.037 14.2 0.3 8.3 6.7 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GAK66170.1 - 0.043 13.7 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 GAK66170.1 - 0.069 13.3 0.8 2.8 8.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAK66170.1 - 0.073 12.2 0.1 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 GAK66170.1 - 0.1 12.7 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 GAK66170.1 - 0.12 12.1 2.1 2.2 8.0 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 GAK66170.1 - 0.14 11.5 0.3 19 4.5 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAK66170.1 - 0.15 11.3 0.0 21 4.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 GAK66170.1 - 0.25 11.9 0.7 18 5.9 0.2 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAK66170.1 - 0.43 10.5 1.7 34 4.3 0.1 3.0 3 0 0 3 3 3 0 NTPase DUF2569 PF10754.9 GAK66170.1 - 0.67 10.4 10.2 0.069 13.6 2.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) ATP11 PF06644.11 GAK66171.1 - 1.6e-76 257.7 2.9 3.4e-76 256.6 3.0 1.4 2 0 0 2 2 2 1 ATP11 protein Death PF00531.22 GAK66171.1 - 0.14 12.3 0.6 3.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Death domain U3_assoc_6 PF08640.11 GAK66172.1 - 1.3e-20 73.2 0.2 1.4e-18 66.7 0.1 2.7 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 GAK66172.1 - 0.00083 20.0 6.8 5.6 8.0 0.0 5.8 3 1 1 4 4 4 2 Tetratricopeptide repeat IFT20 PF14931.6 GAK66172.1 - 0.084 13.1 0.9 0.18 12.0 0.2 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Ras PF00071.22 GAK66173.1 - 9.7e-66 220.4 0.0 1.2e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK66173.1 - 1.2e-33 115.8 0.1 2e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK66173.1 - 5.4e-14 52.0 0.0 6.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAK66173.1 - 1.1e-05 24.9 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK66173.1 - 4e-05 23.7 0.0 0.00012 22.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAK66173.1 - 4.4e-05 23.5 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAK66173.1 - 4.9e-05 23.0 0.1 0.00013 21.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAK66173.1 - 0.00026 20.5 0.0 0.0025 17.3 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 GAK66173.1 - 0.0006 19.3 0.0 0.00076 19.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAK66173.1 - 0.015 15.7 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 GAK66173.1 - 0.025 13.7 0.0 0.32 10.0 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 GAK66173.1 - 0.044 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 GAK66173.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 GAK66173.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Septin AAA PF00004.29 GAK66173.1 - 0.083 13.3 0.0 0.6 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RhoGAP PF00620.27 GAK66174.1 - 1.9e-46 157.6 0.7 1.8e-45 154.5 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 GAK66174.1 - 2.5e-15 56.4 18.5 6.9e-09 35.8 2.6 3.3 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 GAK66174.1 - 9.4e-07 28.6 8.4 9.4e-07 28.6 8.4 4.2 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3450 PF11932.8 GAK66174.1 - 0.0026 17.1 2.6 0.0026 17.1 2.6 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3450) Nup88 PF10168.9 GAK66174.1 - 0.028 12.3 0.1 0.028 12.3 0.1 2.4 3 0 0 3 3 3 0 Nuclear pore component Suppressor_APC PF11414.8 GAK66174.1 - 0.17 12.0 9.3 0.017 15.2 2.5 2.8 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Rotamase_2 PF13145.6 GAK66174.1 - 0.75 10.6 11.9 3.8 8.4 1.3 3.5 3 0 0 3 3 3 0 PPIC-type PPIASE domain Filament PF00038.21 GAK66174.1 - 6.3 6.3 33.6 2 7.9 14.8 2.9 2 1 1 3 3 3 0 Intermediate filament protein RNA_pol_Rpb1_5 PF04998.17 GAK66175.1 - 3.2e-104 348.1 0.1 4.3e-104 347.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 GAK66175.1 - 1.6e-103 346.3 0.0 2.3e-103 345.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 GAK66175.1 - 6.6e-72 241.1 0.0 1.4e-71 240.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 GAK66175.1 - 6.3e-59 199.0 0.1 1.5e-58 197.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 GAK66175.1 - 1.7e-47 160.8 1.2 3.5e-47 159.8 1.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 GAK66175.1 - 4.4e-45 153.4 0.0 8.2e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAK66175.1 - 2e-36 124.2 0.0 4.4e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 GAK66175.1 - 1.9e-17 62.6 189.2 0.0087 16.4 8.8 14.2 9 2 5 15 15 15 14 RNA polymerase Rpb1 C-terminal repeat VHS PF00790.19 GAK66176.1 - 2.3e-38 131.2 4.4 3.5e-38 130.6 0.1 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 GAK66176.1 - 8.7e-17 61.0 10.4 1.8e-16 60.0 10.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 GAK66176.1 - 5.1e-06 26.0 6.4 0.0062 16.4 1.0 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.16 GAK66176.1 - 0.0046 17.2 4.3 0.0092 16.2 4.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger GAT PF03127.14 GAK66176.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 GAT domain OAD_gamma PF04277.13 GAK66176.1 - 0.076 13.6 2.2 0.16 12.6 0.1 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ENTH PF01417.20 GAK66176.1 - 0.23 11.5 0.0 0.41 10.7 0.0 1.3 1 0 0 1 1 1 0 ENTH domain zf-RING_5 PF14634.6 GAK66176.1 - 5.6 7.0 10.6 11 6.1 10.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAK66176.1 - 9.3 6.7 9.4 16 5.9 9.4 1.4 1 0 0 1 1 1 0 Ring finger domain NmrA PF05368.13 GAK66177.1 - 2.3e-47 161.5 0.1 2.8e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAK66177.1 - 2.4e-15 56.9 0.1 3.3e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAK66177.1 - 0.00055 19.0 0.0 0.00082 18.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAK66177.1 - 0.0019 17.7 0.1 0.005 16.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAK66177.1 - 0.006 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 GAK66177.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 GAK66178.1 - 2.3e-18 67.6 0.0 6e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAK66178.1 - 4.8e-15 55.7 0.0 9.4e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAK66178.1 - 0.00086 19.2 0.0 0.007 16.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase DUF3176 PF11374.8 GAK66179.1 - 1.7e-05 24.9 0.4 3e-05 24.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) ABC_tran PF00005.27 GAK66180.1 - 3.1e-43 147.6 0.0 1.2e-21 77.7 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 GAK66180.1 - 1.1e-30 107.2 28.5 7.4e-23 81.6 9.2 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAK66180.1 - 1.2e-09 38.0 2.6 0.0071 15.8 0.2 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAK66180.1 - 4.3e-09 36.6 0.8 0.066 13.0 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAK66180.1 - 8.5e-08 32.3 1.7 0.011 15.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAK66180.1 - 1.9e-06 27.5 0.6 0.05 13.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAK66180.1 - 5.8e-06 26.6 0.1 0.05 13.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAK66180.1 - 7.9e-06 25.9 0.0 0.021 14.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 GAK66180.1 - 0.00014 21.1 0.9 0.33 10.0 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 GAK66180.1 - 0.00026 21.4 12.5 0.023 15.1 0.2 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 GAK66180.1 - 0.00039 21.0 0.8 1 9.8 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAK66180.1 - 0.00047 19.7 0.2 0.78 9.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 GAK66180.1 - 0.00081 18.6 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 GAK66180.1 - 0.0022 17.8 0.1 1.2 8.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 GAK66180.1 - 0.0026 17.4 3.1 0.47 10.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 GAK66180.1 - 0.0044 16.7 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 GAK66180.1 - 0.0055 16.8 1.1 0.14 12.2 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 GAK66180.1 - 0.019 14.7 0.3 4.7 6.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 GAK66180.1 - 0.02 14.6 0.1 5.7 6.6 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 GAK66180.1 - 0.032 13.6 0.8 0.53 9.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 GAK66180.1 - 0.11 12.8 0.0 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 GAK66180.1 - 0.12 12.1 0.1 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 GAK66180.1 - 0.12 12.4 2.9 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 GAK66180.1 - 0.13 12.2 0.5 36 4.3 0.0 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Oleosin PF01277.17 GAK66180.1 - 0.3 10.9 9.9 0.76 9.6 1.4 3.6 2 0 0 2 2 2 0 Oleosin NACHT PF05729.12 GAK66180.1 - 0.32 10.9 3.6 21 5.0 0.0 3.6 4 0 0 4 4 4 0 NACHT domain AMP-binding PF00501.28 GAK66181.1 - 8.8e-41 139.9 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme 2-Hacid_dh_C PF02826.19 GAK66181.1 - 1.1e-37 129.1 0.0 2.2e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.21 GAK66181.1 - 2.3e-35 122.4 0.0 3.8e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II 2-Hacid_dh PF00389.30 GAK66181.1 - 1.7e-09 37.5 0.0 2.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Glyoxalase_4 PF13669.6 GAK66181.1 - 5.4e-05 23.4 0.0 0.0002 21.6 0.0 2.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily XdhC_C PF13478.6 GAK66181.1 - 0.018 15.6 0.3 0.13 12.7 0.0 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 GAK66181.1 - 0.022 15.0 0.0 0.58 10.3 0.0 2.6 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 GAK66181.1 - 0.042 13.2 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family Zn_clus PF00172.18 GAK66182.1 - 0.00071 19.6 8.0 0.0014 18.7 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peroxidase_2 PF01328.17 GAK66184.1 - 2.5e-40 139.0 0.0 3.7e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 DUF459 PF04311.13 GAK66184.1 - 0.061 12.3 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Pro_isomerase PF00160.21 GAK66185.1 - 4.1e-51 173.4 0.1 1.4e-50 171.7 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAK66185.1 - 0.00028 21.6 1.4 0.25 12.3 0.2 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Mito_carr PF00153.27 GAK66186.1 - 8.7e-47 157.0 9.2 3.1e-17 62.3 0.1 4.4 3 1 1 4 4 4 4 Mitochondrial carrier protein CH PF00307.31 GAK66187.1 - 2.7e-47 159.4 0.0 9.7e-25 86.9 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 GAK66187.1 - 8e-21 73.9 0.0 2.2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 GAK66187.1 - 1.2e-10 41.1 0.0 5.6e-06 26.1 0.0 3.2 2 1 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 GAK66187.1 - 2.2e-06 28.1 5.0 0.019 15.5 0.1 3.0 3 0 0 3 3 3 2 Spectrin repeat EF-hand_6 PF13405.6 GAK66187.1 - 7.6e-05 22.3 0.0 0.00037 20.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain CH_2 PF06294.11 GAK66187.1 - 0.0057 16.8 0.0 4.9 7.3 0.0 3.5 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_1 PF00036.32 GAK66187.1 - 0.006 16.1 0.0 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 EF hand Baculo_PEP_C PF04513.12 GAK66187.1 - 0.032 14.3 0.5 0.22 11.6 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DnaG_DnaB_bind PF08278.11 GAK66187.1 - 1.1 9.8 5.0 4.4 7.9 0.2 3.4 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding Cofilin_ADF PF00241.20 GAK66189.1 - 1e-42 144.8 0.5 1.2e-42 144.5 0.5 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HLH PF00010.26 GAK66191.1 - 4e-14 52.3 0.3 7.1e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Prenylcys_lyase PF07156.14 GAK66192.1 - 4e-65 220.3 0.0 1.7e-64 218.3 0.0 1.8 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 GAK66192.1 - 2e-10 40.7 0.0 8.6e-10 38.7 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAK66192.1 - 6.7e-08 32.2 0.1 1.1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAK66192.1 - 1.3e-06 28.3 5.3 3.6e-05 23.5 5.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK66192.1 - 0.00084 19.4 0.0 0.0026 17.8 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAK66192.1 - 0.0026 17.0 0.2 0.02 14.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAK66192.1 - 0.025 13.8 0.1 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Na_H_Exchanger PF00999.21 GAK66193.1 - 6.8e-52 176.5 40.5 9.6e-52 176.0 40.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PP2C PF00481.21 GAK66194.1 - 9.8e-80 267.9 0.0 1.4e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 GAK66195.1 - 3.3e-22 78.4 0.0 5.4e-06 27.0 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66195.1 - 1.2e-08 35.2 0.0 1 9.7 0.0 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK66195.1 - 0.00068 18.4 0.7 0.042 12.5 0.2 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Gmad1 PF10647.9 GAK66195.1 - 0.0015 18.3 0.8 0.0044 16.8 0.4 1.8 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PH_5 PF15405.6 GAK66196.1 - 1.2 9.3 3.2 0.53 10.4 0.3 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain PH_10 PF15411.6 GAK66197.1 - 1.9e-26 92.7 0.0 3.5e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_UBOX PF13445.6 GAK66197.1 - 0.00015 21.7 0.4 0.00033 20.6 0.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAK66197.1 - 0.0013 19.1 1.8 0.002 18.4 0.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAK66197.1 - 0.0017 18.3 0.6 0.005 16.8 0.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain VWA PF00092.28 GAK66197.1 - 0.0031 17.8 0.0 0.025 14.8 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAK66197.1 - 0.0057 16.6 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-C3HC4 PF00097.25 GAK66197.1 - 0.022 14.6 0.2 0.046 13.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK66197.1 - 0.16 11.8 0.8 0.41 10.5 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAK66197.1 - 0.17 11.7 2.3 0.35 10.7 2.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Ribonuc_red_lgC PF02867.15 GAK66198.1 - 7.8e-186 618.7 0.0 1e-185 618.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAK66198.1 - 3.9e-25 87.7 0.0 1.2e-24 86.1 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAK66198.1 - 9.1e-18 64.6 0.2 4e-17 62.6 0.2 2.2 1 0 0 1 1 1 1 ATP cone domain CAP_N PF01213.19 GAK66200.1 - 5.2 6.5 11.9 7.8 5.9 11.8 1.5 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Na_Ca_ex PF01699.24 GAK66201.1 - 6.5e-21 74.9 27.9 5.7e-12 45.8 13.8 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YccF PF03733.13 GAK66201.1 - 2e-14 54.0 7.6 2e-14 54.0 7.6 3.5 3 0 0 3 3 3 1 Inner membrane component domain Otopetrin PF03189.13 GAK66201.1 - 0.074 11.9 0.6 0.16 10.7 0.6 1.5 1 0 0 1 1 1 0 Otopetrin Ufd2P_core PF10408.9 GAK66203.1 - 1.4e-200 668.0 0.1 1.7e-200 667.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GAK66203.1 - 2.9e-28 97.8 0.2 9.3e-28 96.2 0.2 2.0 1 0 0 1 1 1 1 U-box domain DUF5549 PF17703.1 GAK66203.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5549) BCNT PF07572.12 GAK66204.1 - 5.6e-19 68.0 0.7 1.7e-18 66.5 0.7 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF4505 PF14956.6 GAK66206.1 - 1.2e-27 96.8 0.0 2.9e-13 50.0 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4505) Yos1 PF08571.10 GAK66207.1 - 2.2e-30 104.7 1.0 4e-30 103.9 1.0 1.4 1 0 0 1 1 1 1 Yos1-like Ribosomal_S8 PF00410.19 GAK66207.1 - 2.1e-09 37.4 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 DnaJ_C PF01556.18 GAK66208.1 - 5e-34 117.5 0.0 6.7e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAK66208.1 - 3.2e-25 88.0 2.0 4.4e-25 87.6 2.0 1.2 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 GAK66208.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 A repeated domain in UCH-protein UDG PF03167.19 GAK66210.1 - 1.2e-13 51.4 0.0 2.8e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Arrestin_N PF00339.29 GAK66211.1 - 0.00011 22.2 0.0 0.00028 21.0 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAK66211.1 - 0.023 14.4 0.0 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Arrestin_N terminal like Aldedh PF00171.22 GAK66212.1 - 2.6e-157 524.1 0.1 3.2e-157 523.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAK66212.1 - 0.033 13.6 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) NDUFA12 PF05071.16 GAK66213.1 - 1.1e-31 109.6 2.0 1.4e-31 109.2 2.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 MIS13 PF08202.11 GAK66214.1 - 1.6e-18 67.1 9.9 1.6e-18 67.1 9.9 3.6 2 1 0 2 2 2 1 Mis12-Mtw1 protein family UPF0547 PF10571.9 GAK66217.1 - 4.6 7.4 6.9 0.53 10.4 0.4 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Flavokinase PF01687.17 GAK66218.1 - 4e-32 110.8 0.0 1.7e-31 108.8 0.0 1.8 1 1 0 1 1 1 1 Riboflavin kinase Thr_synth_N PF14821.6 GAK66221.1 - 9.7e-24 83.4 0.0 2.4e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 GAK66221.1 - 1.9e-14 53.8 0.0 9e-14 51.6 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TetR_C_7 PF14246.6 GAK66221.1 - 0.03 14.3 0.1 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain RIC3 PF15361.6 GAK66222.1 - 8.5 6.8 7.6 2.1 8.8 0.1 2.9 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 CAP PF00188.26 GAK66223.1 - 6e-16 59.4 2.6 6e-16 59.4 2.6 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family CCSAP PF15748.5 GAK66223.1 - 6.9 6.8 22.5 17 5.4 22.5 1.6 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated XPG_I PF00867.18 GAK66224.1 - 1.8e-08 34.6 0.5 1.5e-07 31.7 0.5 2.4 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAK66224.1 - 3.7e-06 27.3 0.0 7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 GAK66224.1 - 6.1e-05 23.5 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAK66224.1 - 0.0025 18.4 0.0 0.0098 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain Remorin_C PF03763.13 GAK66224.1 - 0.016 15.1 1.0 0.032 14.1 1.0 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region HHH PF00633.23 GAK66224.1 - 0.064 13.2 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3135 PF11333.8 GAK66224.1 - 0.35 11.1 2.2 1.1 9.5 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) V-ATPase_G PF03179.15 GAK66225.1 - 7.4e-35 119.7 14.9 1e-34 119.2 14.9 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 GAK66225.1 - 0.019 15.1 18.4 0.019 15.0 13.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Seryl_tRNA_N PF02403.22 GAK66225.1 - 0.048 13.9 12.1 0.078 13.2 10.8 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rotamase_2 PF13145.6 GAK66225.1 - 0.27 12.1 7.0 0.44 11.4 7.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Symplekin_C PF12295.8 GAK66226.1 - 1.3e-60 204.7 0.4 4.8e-60 202.8 0.1 2.2 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 GAK66226.1 - 4.2e-54 183.6 3.1 9.9e-54 182.4 3.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) FbpA PF05833.11 GAK66226.1 - 0.017 13.9 0.2 0.03 13.1 0.2 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Adaptin_N PF01602.20 GAK66226.1 - 1.8 7.0 11.3 2.7 6.5 3.9 3.3 3 1 0 3 3 3 0 Adaptin N terminal region OPT PF03169.15 GAK66227.1 - 1.9e-170 568.5 55.2 2.2e-170 568.4 55.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_3 PF01494.19 GAK66229.1 - 4.9e-87 292.4 0.0 7.5e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAK66229.1 - 4.9e-49 166.6 0.1 9.7e-49 165.6 0.1 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain AlaDh_PNT_C PF01262.21 GAK66229.1 - 5.7e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAK66229.1 - 8.5e-05 21.4 0.8 0.00012 21.0 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 GAK66229.1 - 0.00032 19.9 1.2 0.0013 17.9 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 GAK66229.1 - 0.00069 19.3 0.1 0.0057 16.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK66229.1 - 0.00073 18.7 0.2 0.0028 16.8 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAK66229.1 - 0.00074 18.8 0.4 0.0043 16.3 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK66229.1 - 0.001 19.2 0.1 0.0025 18.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAK66229.1 - 0.0037 16.5 0.1 0.0069 15.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 GAK66229.1 - 0.034 13.0 0.1 0.06 12.2 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 GAK66229.1 - 0.064 12.6 0.4 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAK66229.1 - 0.078 12.2 0.3 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAK66229.1 - 0.11 11.6 0.2 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAK66229.1 - 0.15 12.6 0.1 0.31 11.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase His_Phos_2 PF00328.22 GAK66230.1 - 5.3e-41 141.2 0.0 7.4e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sec7 PF01369.20 GAK66231.1 - 5.2e-70 234.9 0.0 1.1e-69 233.7 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAK66231.1 - 4.9e-47 159.8 4.1 4.9e-47 159.8 4.1 4.2 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAK66231.1 - 3e-32 110.3 11.0 3.9e-32 110.0 0.1 5.7 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAK66231.1 - 4.4e-21 75.3 0.6 4.4e-21 75.3 0.6 3.4 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 V-ATPase_H_N PF03224.14 GAK66231.1 - 0.09 12.0 0.3 5.6 6.2 0.0 3.1 3 0 0 3 3 3 0 V-ATPase subunit H Mob1_phocein PF03637.17 GAK66232.1 - 1.1e-76 256.6 0.1 1.3e-76 256.4 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family E1-E2_ATPase PF00122.20 GAK66233.1 - 4.3e-37 127.4 3.2 4.3e-37 127.4 3.2 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAK66233.1 - 2e-17 64.2 3.7 1.5e-16 61.3 3.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 GAK66233.1 - 2.8e-16 59.7 8.7 2.8e-16 59.7 8.7 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 GAK66233.1 - 3.6e-14 52.2 0.0 7e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAK66233.1 - 1.1e-07 31.8 0.0 2.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAK66233.1 - 0.00098 18.9 0.0 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAK66233.1 - 0.026 14.9 0.1 0.098 13.0 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAD4L PF06235.11 GAK66233.1 - 0.87 9.6 8.3 0.036 14.0 2.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) Glyco_tranf_2_3 PF13641.6 GAK66234.1 - 1.2e-22 81.0 0.0 1.5e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAK66234.1 - 2.4e-17 63.5 4.2 2.4e-17 63.5 4.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 GAK66234.1 - 3.6e-08 33.1 0.0 5.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAK66234.1 - 6.7e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF982 PF06169.12 GAK66234.1 - 0.059 13.4 1.4 0.065 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF982) Acyl_transf_3 PF01757.22 GAK66235.1 - 6.5e-13 48.5 36.6 1.1e-12 47.7 36.6 1.4 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_16 PF00722.21 GAK66235.1 - 1.3e-07 31.3 0.1 2.2e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sel1 PF08238.12 GAK66236.1 - 1.1e-19 70.5 31.0 0.00028 21.5 0.4 10.1 10 0 0 10 10 10 6 Sel1 repeat TPR_8 PF13181.6 GAK66236.1 - 0.84 10.0 0.0 0.84 10.0 0.0 5.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK66236.1 - 2.4 9.0 10.1 44 5.0 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DRIM PF07539.12 GAK66237.1 - 3.5e-169 564.1 10.1 2.6e-168 561.2 0.2 4.5 4 1 1 5 5 5 2 Down-regulated in metastasis DUF3385 PF11865.8 GAK66237.1 - 0.00029 20.8 1.2 0.17 11.8 0.1 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) DUF3361 PF11841.8 GAK66237.1 - 0.025 14.5 0.3 0.14 12.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Imm5 PF14423.6 GAK66237.1 - 0.3 11.3 1.6 1.6 8.9 1.6 2.3 1 0 0 1 1 1 0 Immunity protein Imm5 Sec7_N PF12783.7 GAK66237.1 - 3 7.7 5.2 5.2 7.0 0.1 3.6 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 GAK66237.1 - 4.9 7.7 8.2 1.2e+02 3.4 0.1 6.2 6 0 0 6 6 6 0 HEAT repeat Glyco_hydro_30 PF02055.16 GAK66238.1 - 1.8e-16 60.1 0.1 3.6e-16 59.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 GAK66238.1 - 9.3e-11 41.5 0.3 1.1e-08 34.6 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 59 7TM-7TMR_HD PF07698.11 GAK66238.1 - 0.012 15.4 0.1 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase AMP-binding PF00501.28 GAK66240.1 - 5.1e-87 292.2 0.0 7.4e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK66240.1 - 2.9e-11 44.2 0.3 7.6e-11 42.8 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Kri1 PF05178.12 GAK66242.1 - 5.7e-29 100.7 10.1 5.7e-29 100.7 10.1 4.4 5 0 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 GAK66242.1 - 8.9e-25 86.7 0.1 8.9e-25 86.7 0.1 3.4 3 0 0 3 3 3 1 KRI1-like family C-terminal p450 PF00067.22 GAK66243.1 - 1.6e-20 73.3 0.1 6.4e-20 71.3 0.0 2.0 2 1 0 2 2 2 1 Cytochrome P450 GTP1_OBG PF01018.22 GAK66244.1 - 2.4e-39 134.4 0.8 2.4e-28 98.7 0.7 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAK66244.1 - 3.9e-19 68.8 0.0 8.3e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.22 GAK66244.1 - 7.6e-06 25.7 0.0 2.8e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FeoB_N PF02421.18 GAK66244.1 - 9.7e-05 21.9 0.1 0.00025 20.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAK66244.1 - 0.0064 16.0 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAK66244.1 - 0.012 14.6 1.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Gtr1_RagA PF04670.12 GAK66244.1 - 0.056 12.8 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 GAK66244.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 GAK66244.1 - 0.18 11.3 0.0 0.69 9.3 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Cellulase PF00150.18 GAK66245.1 - 1.8e-10 40.7 0.2 1.8e-10 40.7 0.2 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RCC1 PF00415.18 GAK66247.1 - 9.4e-47 157.4 6.2 2.2e-11 44.2 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAK66247.1 - 4.1e-23 80.6 22.3 1.3e-06 28.0 0.8 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 GAK66247.1 - 9.6e-11 41.4 7.0 2.3e-10 40.2 7.0 1.7 1 0 0 1 1 1 1 PHD-finger zf-UDP PF14569.6 GAK66247.1 - 0.00065 19.8 1.5 0.002 18.2 1.5 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger PHD_4 PF16866.5 GAK66247.1 - 0.0068 16.5 10.4 0.015 15.4 10.4 1.6 1 0 0 1 1 1 1 PHD-finger Kelch_6 PF13964.6 GAK66247.1 - 0.11 12.8 4.0 17 5.9 0.2 4.1 4 0 0 4 4 4 0 Kelch motif zf-RING-like PF08746.11 GAK66247.1 - 0.64 10.4 4.2 1.9 8.9 4.2 1.8 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.6 GAK66247.1 - 1.2 8.8 6.3 0.37 10.4 3.3 1.8 2 0 0 2 2 2 0 PHD-finger OrfB_Zn_ribbon PF07282.11 GAK66247.1 - 2.7 8.0 4.9 4.9 7.2 0.4 3.0 4 0 0 4 4 4 0 Putative transposase DNA-binding domain Glyco_tranf_2_3 PF13641.6 GAK66248.1 - 4.7e-12 46.3 0.0 9.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAK66248.1 - 2.7e-10 40.5 1.4 5.7e-10 39.4 1.4 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAK66248.1 - 4.9e-06 26.4 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAK66248.1 - 0.00033 20.2 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Transp_cyt_pur PF02133.15 GAK66251.1 - 9.5e-91 304.8 33.7 1.1e-90 304.5 33.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MadM PF03818.13 GAK66251.1 - 0.026 14.4 4.5 0.88 9.5 0.5 3.7 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit Peptidase_M28 PF04389.17 GAK66252.1 - 2.1e-33 115.7 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Na_Pi_cotrans PF02690.15 GAK66252.1 - 0.66 10.1 9.7 0.49 10.5 7.8 1.8 1 1 0 1 1 1 0 Na+/Pi-cotransporter PrmA PF06325.13 GAK66253.1 - 1.8e-12 47.3 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAK66253.1 - 1.4e-10 41.7 0.0 4.8e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK66253.1 - 2.3e-10 40.5 0.0 5.2e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK66253.1 - 9.6e-07 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAK66253.1 - 5.1e-06 26.4 0.0 4.3e-05 23.4 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK66253.1 - 6e-06 26.8 0.0 1.8e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAK66253.1 - 1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 GAK66253.1 - 5.3e-05 23.0 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAK66253.1 - 7.1e-05 23.5 0.1 0.00047 20.9 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAK66253.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAK66253.1 - 0.00062 20.8 3.0 0.0023 18.9 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAK66253.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PCMT PF01135.19 GAK66253.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 GAK66253.1 - 0.0034 16.3 0.0 0.0095 14.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 GAK66253.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HIRA_B PF09453.10 GAK66253.1 - 0.038 13.8 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 HIRA B motif PKcGMP_CC PF16808.5 GAK66253.1 - 0.042 13.7 1.2 0.1 12.5 1.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Albumin_I_a PF16720.5 GAK66253.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Albumin I chain a FtsJ PF01728.19 GAK66253.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Pox_A_type_inc PF04508.12 GAK66253.1 - 0.074 12.9 4.4 0.17 11.8 0.6 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Met_10 PF02475.16 GAK66253.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PRMT5 PF05185.16 GAK66253.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase SQS_PSY PF00494.19 GAK66254.1 - 1.1e-30 107.1 0.0 2.1e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase Prenyltrans PF00432.21 GAK66255.1 - 8.7e-34 114.9 12.1 6.5e-12 45.0 0.1 7.0 5 2 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 GAK66255.1 - 0.0037 16.3 0.0 1.3 8.0 0.0 3.1 2 2 0 3 3 3 2 A-macroglobulin TED domain SQHop_cyclase_N PF13249.6 GAK66255.1 - 0.019 14.1 0.0 9.8 5.2 0.0 3.1 2 1 1 3 3 3 0 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 GAK66255.1 - 0.019 14.1 0.0 8.1 5.4 0.0 3.0 1 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain AAA_9 PF12781.7 GAK66257.1 - 1.3e-73 246.8 0.2 1.3e-73 246.8 0.2 3.3 3 1 0 3 3 2 1 ATP-binding dynein motor region MT PF12777.7 GAK66257.1 - 2.1e-47 161.9 5.3 5.4e-47 160.5 5.3 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 GAK66257.1 - 7.1e-37 127.3 0.8 1.2e-36 126.5 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 GAK66257.1 - 1.5e-31 109.4 0.0 2.9e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 GAK66257.1 - 9.6e-29 99.9 0.0 6.5e-28 97.2 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 GAK66257.1 - 0.00052 19.4 0.0 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Spc7 PF08317.11 GAK66257.1 - 0.015 14.2 30.0 0.0051 15.7 10.9 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4250 PF14056.6 GAK66257.1 - 0.044 13.7 1.0 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Atg14 PF10186.9 GAK66257.1 - 0.84 8.7 15.9 1.3 8.1 8.2 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 GAK66257.1 - 0.96 9.7 25.4 0.28 11.4 2.0 3.5 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 GAK66257.1 - 1.2 9.4 20.3 0.17 12.1 0.9 3.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 GAK66257.1 - 1.4 9.4 30.0 0.22 12.1 1.4 3.6 3 0 0 3 3 3 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 GAK66257.1 - 2 8.2 22.6 1.7 8.4 0.1 3.9 3 1 1 4 4 4 0 Phage minor structural protein GP20 DUF4407 PF14362.6 GAK66257.1 - 2.4 7.4 17.1 15 4.8 11.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Phlebovirus_NSM PF07246.11 GAK66257.1 - 3.6 6.9 8.8 0.6 9.4 0.1 2.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M ZapB PF06005.12 GAK66257.1 - 4 8.0 29.9 1.2 9.7 2.1 5.2 4 1 0 4 4 4 0 Cell division protein ZapB DUF812 PF05667.11 GAK66257.1 - 4.4 6.1 22.0 0.53 9.1 2.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 GAK66257.1 - 6.9 6.7 24.9 0.049 13.7 1.7 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 GAK66257.1 - 8 6.8 17.3 4.7 7.5 0.3 4.4 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 GAK66257.1 - 8.3 6.5 23.6 0.13 12.3 1.7 3.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein eIF2A PF08662.11 GAK66258.1 - 5.2e-83 277.7 0.1 1.8e-81 272.7 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 GAK66258.1 - 8.4e-05 23.3 2.4 11 7.1 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat TauD PF02668.16 GAK66259.1 - 2.7e-28 99.5 0.3 3.8e-28 99.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidohydro_2 PF04909.14 GAK66260.1 - 7.9e-25 88.2 1.0 1.3e-24 87.5 1.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Aldedh PF00171.22 GAK66261.1 - 1.8e-123 412.5 0.0 6.9e-123 410.6 0.0 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAK66261.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DIOX_N PF14226.6 GAK66262.1 - 1.6e-25 90.1 0.1 2.6e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAK66262.1 - 9.4e-17 61.4 0.0 1.9e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG9 PF04109.16 GAK66263.1 - 5.3e-206 685.3 1.9 6.2e-206 685.0 1.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF2231 PF09990.9 GAK66263.1 - 0.0047 17.3 1.6 0.0047 17.3 1.6 3.0 2 1 1 3 3 3 1 Predicted membrane protein (DUF2231) SNF5 PF04855.12 GAK66264.1 - 3.1e-64 217.0 0.0 3.1e-64 217.0 0.0 4.0 3 1 0 3 3 3 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 GAK66264.1 - 0.00095 18.7 1.4 0.0019 17.8 1.4 1.5 1 0 0 1 1 1 1 GATA zinc finger CPSase_L_D2 PF02786.17 GAK66265.1 - 2.7e-75 252.5 0.0 5.3e-75 251.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAK66265.1 - 4.7e-44 149.4 0.1 1.3e-43 148.0 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAK66265.1 - 1.8e-34 118.1 0.0 2.8e-32 111.0 0.0 2.6 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAK66265.1 - 5.4e-11 42.2 0.2 1.2e-10 41.0 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAK66265.1 - 3.1e-10 39.9 0.0 6.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAK66265.1 - 3.3e-07 30.0 0.0 1.6e-06 27.8 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAK66265.1 - 1.8e-06 27.7 0.0 6.1e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 GAK66265.1 - 0.00056 20.0 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAK66265.1 - 0.0009 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 GAK66265.1 - 0.033 13.8 0.0 0.26 10.8 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 GAK66265.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain EMP24_GP25L PF01105.24 GAK66266.1 - 2.6e-44 151.4 0.0 3e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MTCP1 PF08991.10 GAK66267.1 - 2.2e-05 24.6 3.0 3.4e-05 24.0 3.0 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type NDUF_B7 PF05676.13 GAK66267.1 - 2.9e-05 23.7 4.0 3.9e-05 23.3 4.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 GAK66267.1 - 5.5e-05 23.2 4.8 7.6e-05 22.7 4.8 1.2 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.17 GAK66267.1 - 0.0029 17.8 3.4 0.0042 17.3 3.4 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 GAK66267.1 - 0.0056 17.0 2.0 0.0077 16.5 2.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 GAK66267.1 - 0.052 13.8 2.5 0.11 12.8 2.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) TAP_C PF03943.13 GAK66267.1 - 0.065 12.9 0.4 0.097 12.3 0.4 1.3 1 0 0 1 1 1 0 TAP C-terminal domain DUF3326 PF11805.8 GAK66267.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) NuA4 PF09340.10 GAK66268.1 - 2.7e-22 78.4 0.1 6e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF4106 PF13388.6 GAK66270.1 - 0.17 11.1 1.9 0.25 10.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ER_lumen_recept PF00810.18 GAK66271.1 - 4.9e-56 189.7 6.8 4.9e-56 189.7 6.8 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GAK66271.1 - 8.8e-05 22.2 4.4 0.61 9.9 0.0 4.0 3 1 1 4 4 4 2 PQ loop repeat DUF485 PF04341.12 GAK66271.1 - 0.56 10.2 9.7 0.13 12.2 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function, DUF485 DAGK_cat PF00781.24 GAK66272.1 - 2.5e-16 59.5 0.1 4.3e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 GAK66272.1 - 0.11 11.6 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase SMC_N PF02463.19 GAK66273.1 - 8.1e-70 234.7 0.0 1.2e-69 234.1 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAK66273.1 - 6.8e-28 97.3 0.1 1.7e-27 96.0 0.1 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 GAK66273.1 - 3e-19 70.0 0.0 3.9e-11 43.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAK66273.1 - 4.1e-15 56.4 13.2 2.1e-08 34.4 2.9 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAK66273.1 - 4e-07 30.7 91.5 1e-06 29.4 43.2 6.3 2 2 1 3 3 2 1 AAA domain Sec34 PF04136.15 GAK66273.1 - 0.0083 16.0 3.4 0.0083 16.0 3.4 6.4 5 1 1 7 7 7 1 Sec34-like family FmiP_Thoc5 PF09766.9 GAK66273.1 - 0.009 15.3 1.9 0.009 15.3 1.9 6.0 3 3 4 7 7 6 1 Fms-interacting protein/Thoc5 AAA_29 PF13555.6 GAK66273.1 - 0.015 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FA PF08736.11 GAK66273.1 - 0.017 15.2 1.5 0.14 12.3 1.5 2.7 1 0 0 1 1 1 0 FERM adjacent (FA) Phg_2220_C PF09524.10 GAK66273.1 - 0.064 13.3 2.5 5.8 7.1 0.4 3.0 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) ABC_tran PF00005.27 GAK66273.1 - 4.6 7.8 25.6 0.67 10.5 1.8 5.7 3 2 0 3 3 3 0 ABC transporter RRM_1 PF00076.22 GAK66274.1 - 1.9e-06 27.6 0.0 4.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.26 GAK66275.1 - 5.9e-15 55.4 1.6 1.5e-14 54.1 0.0 2.6 3 0 0 3 3 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAK66275.1 - 0.002 18.4 0.0 0.0086 16.4 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Spt20 PF12090.8 GAK66275.1 - 0.011 15.4 11.2 0.011 15.4 11.2 2.0 2 0 0 2 2 2 0 Spt20 family Arb1 PF09692.10 GAK66275.1 - 0.041 13.1 3.6 0.11 11.7 3.6 1.6 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Tweety PF04906.13 GAK66275.1 - 0.097 11.3 6.4 0.055 12.1 0.5 2.2 2 0 0 2 2 2 0 Tweety DUF1664 PF07889.12 GAK66275.1 - 0.49 10.4 22.2 0.052 13.6 2.5 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) eIF_4EBP PF05456.11 GAK66275.1 - 1 9.3 5.8 4.5 7.2 5.8 2.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Exonuc_VII_L PF02601.15 GAK66275.1 - 1.6 8.2 21.7 2.2 7.8 5.0 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Bul1_N PF04425.12 GAK66275.1 - 2.4 6.8 9.7 0.058 12.2 2.0 2.0 2 0 0 2 2 2 0 Bul1 N terminus DUF2721 PF11026.8 GAK66275.1 - 8.2 6.3 7.0 32 4.4 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) FAM184 PF15665.5 GAK66275.1 - 9.2 6.0 41.4 2.2 8.0 15.0 2.5 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B BRO1 PF03097.18 GAK66279.1 - 6.7e-16 58.1 0.0 1.4e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 BRO1-like domain Spc7 PF08317.11 GAK66280.1 - 0.0013 17.6 18.6 0.0013 17.6 18.6 8.1 2 1 6 8 8 8 5 Spc7 kinetochore protein Atg14 PF10186.9 GAK66280.1 - 0.0048 16.0 5.6 0.0048 16.0 5.6 7.4 2 1 4 6 6 6 2 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 GAK66280.1 - 0.0065 16.8 2.6 0.0065 16.8 2.6 10.0 7 4 4 11 11 11 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 BST2 PF16716.5 GAK66280.1 - 0.0081 16.7 8.8 0.0081 16.7 8.8 9.9 4 3 8 12 12 12 2 Bone marrow stromal antigen 2 APG6_N PF17675.1 GAK66280.1 - 0.0096 16.5 0.4 0.0096 16.5 0.4 8.6 2 1 8 10 10 10 2 Apg6 coiled-coil region CCB2_CCB4 PF11152.8 GAK66280.1 - 1.9 7.7 6.1 0.53 9.6 1.9 2.4 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Fez1 PF06818.15 GAK66280.1 - 5.8 7.3 113.4 1.4 9.4 10.5 7.6 2 1 5 8 8 8 0 Fez1 PhoLip_ATPase_C PF16212.5 GAK66281.1 - 1.9e-73 247.3 22.0 3.5e-73 246.4 22.0 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAK66281.1 - 1e-27 95.6 1.5 2.5e-27 94.4 1.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAK66281.1 - 1.1e-12 47.8 0.0 3.7e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAK66281.1 - 1.4e-11 45.1 1.9 3.8e-07 30.6 0.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAK66281.1 - 0.00024 20.7 0.0 0.00096 18.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAK66281.1 - 0.0036 17.1 0.2 0.022 14.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pinin_SDK_memA PF04696.13 GAK66282.1 - 7.4e-11 42.2 12.0 2.9e-10 40.3 12.0 1.9 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Cue1_U7BR PF18499.1 GAK66282.1 - 0.024 14.7 0.6 0.051 13.6 0.6 1.5 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 vWA-TerF-like PF10138.9 GAK66283.1 - 1.4e-08 35.1 0.0 2.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 GAK66283.1 - 0.0061 16.8 0.0 0.054 13.7 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Methyltransf_34 PF11312.8 GAK66283.1 - 0.042 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase VWA_2 PF13519.6 GAK66283.1 - 0.066 13.9 0.0 0.2 12.3 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain HEAT_EZ PF13513.6 GAK66284.1 - 1.3e-32 111.8 27.1 1.4e-13 51.0 0.0 10.7 11 2 2 13 13 11 6 HEAT-like repeat HEAT PF02985.22 GAK66284.1 - 5.6e-20 69.7 12.8 0.0018 18.4 0.0 9.7 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 GAK66284.1 - 2.2e-14 53.6 0.8 0.00026 21.3 0.0 7.2 5 3 3 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GAK66284.1 - 2.3e-10 40.9 0.0 0.0004 20.9 0.1 4.1 2 2 1 3 3 3 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 GAK66284.1 - 8.2e-07 28.9 0.0 3.1e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cnd1 PF12717.7 GAK66284.1 - 4.7e-06 26.8 0.0 0.43 10.6 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAK66284.1 - 0.0015 18.5 3.8 1.4 9.1 0.0 5.2 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 GAK66284.1 - 0.0032 16.6 2.8 6.3 5.8 0.0 3.9 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 GAK66284.1 - 0.0055 16.3 0.0 13 5.2 0.0 4.6 4 1 1 5 5 5 0 CLASP N terminal Cnd3 PF12719.7 GAK66284.1 - 0.013 14.7 0.2 4.1 6.5 0.1 3.4 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain DUF3437 PF11919.8 GAK66284.1 - 0.028 14.3 0.0 5.7 6.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Ecm29 PF13001.7 GAK66284.1 - 0.04 12.6 0.0 23 3.5 0.0 3.6 3 1 0 4 4 4 0 Proteasome stabiliser UNC45-central PF11701.8 GAK66284.1 - 0.08 12.9 0.0 0.58 10.1 0.0 2.4 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central TIP120 PF08623.10 GAK66284.1 - 0.12 12.2 0.1 8.1 6.2 0.1 3.3 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) CENP-B_dimeris PF09026.10 GAK66284.1 - 0.14 12.5 10.1 0.42 11.0 10.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAK66284.1 - 1.6 9.1 6.7 3.6 8.0 6.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GAK66284.1 - 7 5.9 13.2 6 6.1 11.2 1.8 2 0 0 2 2 2 0 NOA36 protein RRM_1 PF00076.22 GAK66285.1 - 3.1e-32 110.2 0.1 2e-08 33.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAK66285.1 - 1.9e-10 40.5 0.0 0.01 15.7 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 GAK66285.1 - 0.073 13.1 0.0 9.7 6.3 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif RRM_7 PF16367.5 GAK66285.1 - 0.1 12.7 0.0 1.3e+02 2.8 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif Mito_carr PF00153.27 GAK66286.1 - 4.3e-64 212.5 1.2 1.6e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.22 GAK66287.1 - 3.3e-32 111.9 9.5 6.7e-32 110.9 9.5 1.5 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAK66287.1 - 1.8e-10 41.3 0.0 3.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cpn60_TCP1 PF00118.24 GAK66288.1 - 1e-153 512.6 0.3 1.1e-153 512.4 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 GAK66288.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 MftR C-terminal domain GIDA PF01134.22 GAK66289.1 - 5.9e-132 440.5 0.0 8.8e-132 439.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GAK66289.1 - 3.3e-57 194.1 0.0 4.8e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 GAK66289.1 - 3.6e-08 33.0 0.8 1.5e-07 31.0 0.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAK66289.1 - 1.8e-06 27.6 0.5 2.7e-06 27.0 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK66289.1 - 0.00029 20.0 2.4 0.00093 18.4 2.4 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAK66289.1 - 0.0026 16.5 1.8 0.076 11.7 0.6 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAK66289.1 - 0.017 14.4 0.1 0.26 10.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAK66289.1 - 0.028 13.5 0.6 0.5 9.4 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GAK66289.1 - 0.049 12.9 0.2 0.085 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAK66289.1 - 0.13 11.5 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAK66289.1 - 0.19 12.3 0.7 0.43 11.2 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAK66289.1 - 0.2 11.7 0.7 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAK66289.1 - 0.58 9.3 3.3 1 8.5 0.5 2.4 2 1 0 3 3 3 0 FAD binding domain PH PF00169.29 GAK66290.1 - 0.00049 20.6 0.0 0.0049 17.4 0.0 2.4 1 1 0 1 1 1 1 PH domain SLD3 PF08639.10 GAK66291.1 - 6.8e-13 48.2 0.7 1e-12 47.6 0.7 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 Glyco_hydro_31 PF01055.26 GAK66292.1 - 1.9e-127 426.1 1.0 3.6e-127 425.2 1.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAK66292.1 - 6.8e-21 74.4 0.3 1.6e-19 70.0 0.1 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 GAK66292.1 - 3.9e-06 27.0 0.0 1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) TP_methylase PF00590.20 GAK66293.1 - 9.3e-19 68.2 0.4 2.1e-18 67.1 0.0 1.8 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sad1_UNC PF07738.13 GAK66294.1 - 2.9e-25 88.8 0.0 4.9e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal EVI2A PF05399.11 GAK66294.1 - 0.11 12.1 0.1 0.42 10.2 0.1 2.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MFS_1 PF07690.16 GAK66295.1 - 3.6e-11 42.6 52.2 2.8e-09 36.4 52.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Myb_Cef PF11831.8 GAK66296.1 - 8.1e-57 192.5 5.1 8.1e-57 192.5 5.1 3.1 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GAK66296.1 - 3.5e-23 81.5 5.7 2.9e-11 43.4 0.9 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAK66296.1 - 3.8e-19 68.7 6.8 4.7e-13 49.2 2.7 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain bZIP_1 PF00170.21 GAK66297.1 - 2.9e-06 27.3 0.8 8.8e-06 25.7 0.8 1.8 1 0 0 1 1 1 1 bZIP transcription factor CRF1 PF10380.9 GAK66297.1 - 0.001 19.4 0.1 0.0041 17.4 0.1 2.1 1 0 0 1 1 1 1 Transcription factor CRF1 ATG16 PF08614.11 GAK66297.1 - 0.06 13.6 0.4 0.06 13.6 0.4 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 GAK66297.1 - 6.7 6.9 9.3 0.59 10.3 4.0 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Uso1_p115_head PF04869.14 GAK66298.1 - 2.5e-57 194.4 0.0 2e-53 181.6 0.0 3.6 3 0 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 GAK66298.1 - 1.3e-09 38.4 30.6 1.3e-09 38.4 30.6 8.4 3 1 5 8 8 8 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 GAK66298.1 - 0.00037 20.3 0.0 0.00087 19.2 0.0 1.6 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Golgin_A5 PF09787.9 GAK66298.1 - 0.0061 16.1 15.1 0.0061 16.1 15.1 4.2 1 1 3 4 4 4 1 Golgin subfamily A member 5 Atx10homo_assoc PF09759.9 GAK66298.1 - 0.11 12.5 7.2 0.44 10.6 0.0 5.3 6 0 0 6 6 6 0 Spinocerebellar ataxia type 10 protein domain BLOC1_2 PF10046.9 GAK66298.1 - 2 8.7 72.2 0.48 10.8 6.9 7.9 2 2 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TetR_C_24 PF17932.1 GAK66298.1 - 2.2 8.5 7.3 29 5.0 0.5 3.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Spo12 PF05032.12 GAK66299.1 - 2.4e-10 40.1 0.8 5.5e-10 39.0 0.8 1.6 1 0 0 1 1 1 1 Spo12 family EcKinase PF02958.20 GAK66300.1 - 5.3e-18 65.4 0.0 3e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 GAK66300.1 - 3.7e-12 46.7 2.1 7e-12 45.8 2.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAK66300.1 - 1.3e-07 30.8 0.0 2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 GAK66300.1 - 0.22 11.1 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase POB3_N PF17292.2 GAK66301.1 - 1.6e-27 95.7 0.0 3.5e-24 85.0 0.0 2.4 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 GAK66301.1 - 8.7e-24 83.2 0.0 3.4e-23 81.3 0.0 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 GAK66301.1 - 6.1e-23 81.0 0.0 1.2e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3780 PF12635.7 GAK66301.1 - 0.12 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) THOC2_N PF16134.5 GAK66301.1 - 0.86 8.2 3.7 1.6 7.2 3.7 1.4 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus BUD22 PF09073.10 GAK66301.1 - 3 7.1 17.0 2.4 7.4 11.9 2.1 2 0 0 2 2 2 0 BUD22 TFIIA PF03153.13 GAK66301.1 - 5.7 6.8 12.7 0.19 11.7 4.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1899 PF08953.11 GAK66302.1 - 1.8e-31 107.8 0.8 3.9e-31 106.7 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 GAK66302.1 - 6.6e-18 64.3 1.5 1.1e-16 60.4 0.4 2.4 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 GAK66302.1 - 2e-09 37.9 6.6 0.016 16.1 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66302.1 - 6.9e-06 26.3 0.0 1.3 9.3 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PspA_IM30 PF04012.12 GAK66302.1 - 0.00026 20.6 0.7 0.00041 20.0 0.7 1.2 1 0 0 1 1 1 1 PspA/IM30 family ZapB PF06005.12 GAK66302.1 - 0.15 12.5 3.6 0.25 11.8 3.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 GAK66302.1 - 0.29 11.5 0.7 0.61 10.4 0.7 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family CBP_BcsO PF17037.5 GAK66302.1 - 1.8 8.7 12.3 3.4 7.8 12.3 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO RNase_T PF00929.24 GAK66303.1 - 1.4e-27 97.3 0.0 1.7e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease CRAL_TRIO PF00650.20 GAK66304.1 - 1.5e-29 102.7 0.0 2.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAK66304.1 - 1.8e-08 34.5 0.5 4.2e-08 33.3 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAK66304.1 - 3.3e-08 33.8 0.0 5.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pantoate_transf PF02548.15 GAK66305.1 - 1.7e-84 283.3 0.7 1.6e-82 276.8 0.7 2.3 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 GAK66305.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Zn_clus PF00172.18 GAK66306.1 - 9.8e-08 32.0 7.5 1.6e-07 31.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myc_target_1 PF15179.6 GAK66306.1 - 0.078 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 Ceramidase PF05875.12 GAK66307.1 - 1.3e-83 280.5 4.4 1.4e-83 280.3 4.4 1.0 1 0 0 1 1 1 1 Ceramidase HlyIII PF03006.20 GAK66307.1 - 0.24 11.1 11.0 0.36 10.5 9.5 1.9 1 1 1 2 2 2 0 Haemolysin-III related Glyco_hydro_10 PF00331.20 GAK66308.1 - 2.9e-51 174.5 0.0 3.5e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 TrkH PF02386.16 GAK66309.1 - 9.2e-102 341.0 5.0 3e-98 329.5 2.2 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 GAK66309.1 - 0.18 11.8 5.0 0.9 9.6 5.0 2.2 1 0 0 1 1 1 0 Ion channel DUF2076 PF09849.9 GAK66310.1 - 0.0032 17.6 3.0 0.0035 17.4 3.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) AIF_C PF14721.6 GAK66310.1 - 0.046 14.1 3.4 0.053 13.9 3.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med19 PF10278.9 GAK66310.1 - 0.15 12.0 16.1 0.69 9.8 16.1 1.9 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Zip PF02535.22 GAK66310.1 - 0.61 9.3 2.4 0.59 9.3 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GAK66310.1 - 1.1 8.0 3.7 1.1 8.0 3.7 1.2 1 0 0 1 1 1 0 Presenilin RNA_polI_A34 PF08208.11 GAK66310.1 - 1.7 8.7 19.9 2.3 8.3 19.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3408 PF11888.8 GAK66310.1 - 1.9 8.6 12.5 2.5 8.3 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peptidase_S49_N PF08496.10 GAK66310.1 - 2.1 8.4 8.4 3 7.9 8.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PKI PF02827.16 GAK66310.1 - 2.9 8.2 12.8 1.2e+02 3.0 12.8 2.7 1 1 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Cytomega_UL84 PF06284.11 GAK66310.1 - 4.9 5.5 7.3 7.7 4.8 7.3 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein UPF0016 PF01169.19 GAK66311.1 - 7.4e-41 138.3 25.7 7.9e-21 74.2 9.4 2.9 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Sacchrp_dh_NADP PF03435.18 GAK66311.1 - 7e-16 58.7 0.0 1.1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 GAK66311.1 - 0.0029 17.7 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAK66311.1 - 0.021 15.3 0.0 0.059 13.8 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 GAK66311.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Mntp PF02659.15 GAK66311.1 - 0.023 14.5 0.1 0.023 14.5 0.1 2.5 2 0 0 2 2 2 0 Putative manganese efflux pump Epimerase PF01370.21 GAK66311.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TerC PF03741.16 GAK66311.1 - 0.11 12.2 6.6 0.3 10.8 3.3 2.3 2 0 0 2 2 2 0 Integral membrane protein TerC family Frataxin_Cyay PF01491.16 GAK66313.1 - 4.7e-39 132.8 0.0 7.8e-39 132.1 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain DUF3725 PF12523.8 GAK66313.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Aminotran_1_2 PF00155.21 GAK66314.1 - 2.4e-59 201.4 0.0 3e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase PF00756.20 GAK66315.1 - 1.7e-48 165.5 0.0 2e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 GAK66315.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAK66315.1 - 0.0039 16.7 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAK66315.1 - 0.0049 15.8 0.0 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 GAK66315.1 - 0.022 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 GAK66315.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold MIF4G PF02854.19 GAK66317.1 - 5.8e-59 199.3 1.0 8.5e-59 198.7 1.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 GAK66317.1 - 1.9e-20 72.8 0.2 5.8e-20 71.2 0.2 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 GAK66317.1 - 5.5e-08 32.8 0.1 2e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 MA3 domain DUF5345 PF17280.2 GAK66318.1 - 0.34 10.9 2.7 0.98 9.4 2.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Hydrophobin PF01185.18 GAK66319.1 - 3.1e-14 53.4 11.5 1e-13 51.7 11.5 2.0 1 0 0 1 1 1 1 Fungal hydrophobin Ribonuclease PF00545.20 GAK66319.1 - 1.5e-07 32.1 0.1 29 5.5 0.0 7.0 4 2 3 7 7 7 2 ribonuclease DUF2018 PF09442.10 GAK66319.1 - 0.012 16.6 1.7 66 4.6 0.0 6.3 5 3 2 7 7 7 0 Domain of unknown function (DUF2018) NLE PF08154.12 GAK66319.1 - 1.2 9.8 7.2 2.4e+02 2.4 0.1 6.3 4 1 1 6 6 6 0 NLE (NUC135) domain HSP70 PF00012.20 GAK66320.1 - 2.8e-229 762.3 4.1 3.6e-229 761.9 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAK66320.1 - 9.2e-18 64.1 0.6 1.7e-17 63.2 0.6 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 GAK66320.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GAK66320.1 - 0.014 14.4 0.6 0.095 11.7 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Zincin_2 PF10103.9 GAK66320.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase ATP-synt_DE PF00401.20 GAK66320.1 - 5.7 7.3 6.3 21 5.5 3.6 2.9 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Ribosomal_S2 PF00318.20 GAK66321.1 - 3.9e-57 192.9 0.0 8.5e-56 188.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 ABC_membrane PF00664.23 GAK66322.1 - 1.9e-85 286.8 16.3 3e-45 155.0 2.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK66322.1 - 6.7e-60 201.6 0.0 9.8e-29 100.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAK66322.1 - 9.3e-14 51.4 1.6 0.00035 20.1 0.0 4.1 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAK66322.1 - 2.9e-11 44.0 6.3 8.5e-07 29.5 0.3 4.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAK66322.1 - 8.2e-08 32.6 1.1 0.13 12.5 0.4 4.3 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 GAK66322.1 - 7.9e-07 29.2 0.1 0.19 11.5 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAK66322.1 - 5e-06 26.2 0.0 0.046 13.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 GAK66322.1 - 7.7e-06 26.2 0.2 0.074 13.1 0.0 3.4 4 0 0 4 4 3 2 Helicase HerA, central domain ABC_ATPase PF09818.9 GAK66322.1 - 3.6e-05 22.8 0.2 0.052 12.3 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 GAK66322.1 - 7.6e-05 22.5 0.5 1.8 8.3 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.6 GAK66322.1 - 9.5e-05 22.2 0.1 3.7 7.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 GAK66322.1 - 0.00011 21.5 0.1 0.24 10.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.14 GAK66322.1 - 0.00026 21.0 0.1 2.2 8.3 0.0 3.8 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAK66322.1 - 0.00038 21.0 0.1 0.32 11.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 GAK66322.1 - 0.00047 20.3 0.8 0.86 9.8 0.2 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAK66322.1 - 0.00052 20.0 0.2 0.69 9.8 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase SbcCD_C PF13558.6 GAK66322.1 - 0.0012 19.0 1.4 1.4 9.2 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 GAK66322.1 - 0.0025 17.6 0.1 0.3 10.8 0.1 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 GAK66322.1 - 0.0026 17.4 0.6 2.2 7.8 0.0 4.2 5 0 0 5 5 5 1 AAA domain AAA_28 PF13521.6 GAK66322.1 - 0.003 17.8 0.1 2.8 8.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 GAK66322.1 - 0.0044 17.4 1.1 56 4.2 0.0 4.5 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAK66322.1 - 0.0058 17.0 0.0 4.3 7.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 GAK66322.1 - 0.0085 15.8 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 GAK66322.1 - 0.015 15.2 0.1 7.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase G-alpha PF00503.20 GAK66322.1 - 0.016 14.4 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit tRNA_lig_kinase PF08303.11 GAK66322.1 - 0.024 14.7 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 tRNA ligase kinase domain Mg_chelatase PF01078.21 GAK66322.1 - 0.032 13.6 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 GAK66322.1 - 0.062 13.8 0.0 5.5 7.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF1601 PF07671.11 GAK66322.1 - 0.085 12.7 0.2 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) NACHT PF05729.12 GAK66322.1 - 0.097 12.6 0.2 17 5.3 0.0 3.3 4 0 0 4 4 3 0 NACHT domain AAA_24 PF13479.6 GAK66322.1 - 0.12 12.1 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 GAK66322.1 - 0.12 12.5 0.3 13 5.8 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activ_2 PF14532.6 GAK66322.1 - 0.17 12.0 0.5 27 4.8 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain ATPase PF06745.13 GAK66322.1 - 0.17 11.2 3.3 33 3.7 0.0 3.4 3 0 0 3 3 3 0 KaiC Cyclin_N PF00134.23 GAK66324.1 - 1.1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAK66324.1 - 7.1e-05 23.2 4.0 7.1e-05 23.2 4.0 2.9 2 2 0 2 2 2 1 Cyclin adh_short PF00106.25 GAK66328.1 - 4.3e-39 134.0 0.6 6.4e-39 133.4 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK66328.1 - 4.3e-22 78.8 0.3 5.9e-22 78.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK66328.1 - 9.9e-07 28.8 0.1 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAK66328.1 - 0.0035 16.5 0.1 0.0053 15.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAK66328.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Dcc1 PF09724.9 GAK66328.1 - 0.2 10.9 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 tRNA-synt_2 PF00152.20 GAK66329.1 - 2e-90 303.1 0.0 2.6e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAK66329.1 - 6.6e-12 45.3 0.0 1.6e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain BOF PF04076.13 GAK66329.1 - 0.07 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein Gcn1_N PF12074.8 GAK66330.1 - 9.8e-72 242.2 7.6 9.8e-72 242.2 7.6 5.3 6 1 1 7 7 7 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 GAK66330.1 - 4.5e-29 98.0 38.1 0.39 11.1 0.1 22.4 25 0 0 25 25 22 5 HEAT repeat HEAT_2 PF13646.6 GAK66330.1 - 1.7e-23 82.8 56.4 6.1e-06 26.5 0.0 15.8 11 4 8 19 19 18 8 HEAT repeats HEAT_EZ PF13513.6 GAK66330.1 - 4.1e-21 75.1 47.8 8.6e-05 22.9 0.0 19.9 16 3 3 20 20 18 7 HEAT-like repeat Cnd1 PF12717.7 GAK66330.1 - 5.9e-14 52.4 0.1 0.22 11.6 0.0 10.6 9 3 4 13 13 12 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 GAK66330.1 - 1.2e-12 47.9 0.1 0.004 16.7 0.0 6.8 4 1 2 6 6 6 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 GAK66330.1 - 2.4e-08 34.5 0.0 2.1 9.0 0.0 8.1 8 2 1 9 9 7 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 GAK66330.1 - 5.2e-05 23.4 0.0 0.19 12.0 0.0 5.1 4 1 0 4 4 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 GAK66330.1 - 8.4e-05 22.4 18.1 0.029 14.1 0.1 7.6 8 0 0 8 8 8 2 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.7 GAK66330.1 - 0.00011 22.4 3.1 0.32 11.3 0.2 4.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 GAK66330.1 - 0.00024 20.4 0.2 1.1 8.4 0.0 4.2 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 GAK66330.1 - 0.00025 19.7 9.3 0.045 12.3 0.0 6.0 6 2 1 7 7 7 2 Adaptin N terminal region DUF3437 PF11919.8 GAK66330.1 - 0.00038 20.3 1.1 1.6 8.7 0.0 5.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) Arm PF00514.23 GAK66330.1 - 0.0011 18.9 13.9 7.9 6.7 0.1 9.4 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 GAK66330.1 - 0.013 14.6 0.0 14 4.7 0.0 4.1 3 1 0 3 3 3 0 Dopey, N-terminal MMS19_C PF12460.8 GAK66330.1 - 0.079 12.1 5.7 42 3.1 0.0 5.9 7 1 0 8 8 8 0 RNAPII transcription regulator C-terminal UME PF08064.13 GAK66330.1 - 0.22 11.5 6.1 38 4.3 0.0 6.4 7 1 1 8 8 7 0 UME (NUC010) domain Phasin PF05597.11 GAK66330.1 - 0.68 9.9 6.6 1.3 9.1 4.9 2.4 2 0 0 2 2 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pox_RNA_Pol_19 PF05320.12 GAK66330.1 - 0.92 9.5 4.2 1.7 8.6 3.5 1.7 2 0 0 2 2 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit FANCI_S2 PF14676.6 GAK66330.1 - 6.4 7.1 10.1 0.79 10.0 0.1 4.7 6 0 0 6 6 4 0 FANCI solenoid 2 Mito_carr PF00153.27 GAK66331.1 - 3.9e-49 164.5 1.0 3e-15 55.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Anoctamin PF04547.12 GAK66332.1 - 7.5e-102 341.5 0.1 9.8e-102 341.1 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel LSM PF01423.22 GAK66333.1 - 2.6e-16 59.1 0.0 6e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 LSM domain GRP PF07172.11 GAK66333.1 - 1.9 9.2 15.4 3 8.6 15.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family zf-CCCH_2 PF14608.6 GAK66334.1 - 1.2e-16 60.5 37.0 5.3e-05 23.5 6.4 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 GAK66334.1 - 0.028 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) 2-ph_phosp PF04029.14 GAK66334.1 - 0.047 12.9 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase EF-hand_6 PF13405.6 GAK66337.1 - 5.6e-11 41.5 1.7 2.5e-05 23.8 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAK66337.1 - 1.2e-10 41.7 0.0 4e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAK66337.1 - 1.6e-08 33.5 3.6 0.0003 20.1 0.2 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAK66337.1 - 1.9e-05 23.9 1.3 0.019 14.4 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAK66337.1 - 0.0037 17.1 0.9 1.2 9.0 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 GAK66337.1 - 0.026 14.8 0.0 7.6 6.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain NAPRTase PF04095.16 GAK66339.1 - 1.2e-55 188.7 0.0 1.9e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 GAK66339.1 - 2.9e-36 124.6 0.0 4.4e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain FCD PF07729.12 GAK66339.1 - 0.22 11.9 1.6 0.45 10.9 0.2 2.1 2 0 0 2 2 2 0 FCD domain Glyco_transf_90 PF05686.12 GAK66340.1 - 1.3e-27 96.7 1.9 9.6e-24 84.0 0.6 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 UBA_4 PF14555.6 GAK66340.1 - 0.16 11.8 0.0 0.48 10.3 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain E1_dh PF00676.20 GAK66342.1 - 2e-63 214.1 0.0 2.7e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 GAK66342.1 - 1.9e-62 210.1 0.0 3e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GAK66342.1 - 1.2e-47 161.4 0.0 3e-47 160.1 0.0 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GAK66342.1 - 1.3e-14 53.5 1.1 2.8e-14 52.4 0.2 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Y_phosphatase PF00102.27 GAK66343.1 - 1.9e-51 174.9 0.2 1.8e-26 93.2 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAK66343.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Rhodanese PF00581.20 GAK66343.1 - 0.15 12.6 0.0 1.2 9.7 0.0 2.5 2 1 0 2 2 2 0 Rhodanese-like domain Cwf_Cwc_15 PF04889.12 GAK66344.1 - 9.1e-69 231.9 19.0 1.1e-68 231.7 19.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 GAK66344.1 - 0.025 14.8 13.3 0.042 14.1 13.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 GAK66344.1 - 0.045 12.0 17.2 0.051 11.8 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 GAK66344.1 - 0.051 11.4 2.1 0.054 11.3 2.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 GAK66344.1 - 0.11 11.9 21.1 0.15 11.5 21.1 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GAK66344.1 - 0.39 10.3 13.1 0.6 9.7 13.1 1.3 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.11 GAK66344.1 - 0.42 8.6 6.4 0.5 8.4 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFMR_assoc PF16596.5 GAK66344.1 - 0.46 10.9 6.0 0.83 10.1 6.0 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR NOA36 PF06524.12 GAK66344.1 - 0.56 9.5 14.4 0.88 8.8 14.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 GAK66344.1 - 0.95 8.8 9.4 1.1 8.6 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Roughex PF06020.11 GAK66344.1 - 1 8.4 13.2 1.3 8.0 13.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein FAM176 PF14851.6 GAK66344.1 - 1.4 8.6 14.6 2.3 7.9 14.6 1.4 1 0 0 1 1 1 0 FAM176 family PA26 PF04636.13 GAK66344.1 - 2 7.3 4.7 2.5 6.9 4.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SpoIIIAH PF12685.7 GAK66344.1 - 2.4 7.9 13.2 3.1 7.6 13.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 GAK66344.1 - 2.4 7.3 3.8 2.7 7.1 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RPN2_C PF18004.1 GAK66344.1 - 2.4 8.0 11.0 3.9 7.4 11.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 GAK66344.1 - 3 6.0 16.4 3.8 5.7 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 GAK66344.1 - 3.1 7.1 7.8 4.4 6.6 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Neur_chan_memb PF02932.16 GAK66344.1 - 4 7.4 4.2 5.3 7.0 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paf1 PF03985.13 GAK66344.1 - 8.7 5.2 18.3 12 4.8 18.3 1.2 1 0 0 1 1 1 0 Paf1 FKBP_C PF00254.28 GAK66345.1 - 2.4e-35 120.7 0.0 3e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 GAK66346.1 - 2.1e-71 240.4 0.0 2.5e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66346.1 - 3.3e-36 124.9 0.0 4.4e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK66346.1 - 0.0019 17.6 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAK66346.1 - 0.022 14.1 0.0 0.068 12.5 0.0 1.8 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK66346.1 - 0.09 12.7 0.4 0.52 10.2 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family UPF0220 PF05255.11 GAK66347.1 - 2.1e-52 177.0 0.1 8.4e-52 175.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0220) ApbA PF02558.16 GAK66347.1 - 1.2e-26 93.2 0.2 1.8e-26 92.6 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAK66347.1 - 2e-25 89.4 0.0 3.8e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 GAK66347.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 GAK66347.1 - 0.083 13.5 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase polyprenyl_synt PF00348.17 GAK66348.1 - 4.5e-55 186.5 0.0 6.6e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3140 PF11338.8 GAK66348.1 - 0.15 12.5 0.1 0.32 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) RNA_pol_Rpb8 PF03870.15 GAK66349.1 - 1.6e-45 154.7 0.0 1.9e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 E1-E2_ATPase PF00122.20 GAK66350.1 - 4e-48 163.3 0.1 4e-48 163.3 0.1 3.3 6 0 0 6 6 6 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAK66350.1 - 2.6e-32 112.0 0.3 7.4e-32 110.5 0.3 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAK66350.1 - 4.7e-22 79.3 4.9 4.5e-21 76.1 4.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK66350.1 - 5.3e-12 45.3 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAK66350.1 - 6.7e-10 38.9 0.0 2.4e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAK66350.1 - 0.0013 18.6 3.5 0.011 15.5 3.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAK66350.1 - 0.018 15.4 0.0 0.062 13.7 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2127 PF09900.9 GAK66350.1 - 0.11 12.7 5.0 0.25 11.6 1.6 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2127) MrpF_PhaF PF04066.13 GAK66350.1 - 1.1 9.7 7.8 1.2 9.6 0.2 4.4 3 1 1 4 4 4 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Med17 PF10156.9 GAK66351.1 - 1.8e-10 40.1 0.0 2.4e-06 26.6 0.0 3.1 3 0 0 3 3 3 3 Subunit 17 of Mediator complex IBN_N PF03810.19 GAK66351.1 - 0.032 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain Lectin_leg-like PF03388.13 GAK66352.1 - 1.4e-63 214.4 0.1 2.9e-63 213.3 0.0 1.4 2 0 0 2 2 2 1 Legume-like lectin family Lectin_legB PF00139.19 GAK66352.1 - 0.001 18.7 0.0 0.93 9.0 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain FAD_binding_4 PF01565.23 GAK66353.1 - 2.9e-11 43.2 0.2 0.00014 21.6 0.1 2.8 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.12 GAK66353.1 - 3.7e-07 30.2 0.0 1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like Bromodomain PF00439.25 GAK66354.1 - 2.9e-19 68.9 0.2 5.8e-19 67.9 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 GAK66354.1 - 0.00018 21.4 0.0 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 1 Bromodomain associated Adeno_VII PF03228.14 GAK66354.1 - 0.0059 17.2 0.1 0.21 12.2 0.1 2.7 2 0 0 2 2 2 1 Adenoviral core protein VII DFP PF04127.15 GAK66354.1 - 0.097 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TBCC_N PF16752.5 GAK66354.1 - 0.21 12.0 2.0 0.58 10.6 0.0 2.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain adh_short_C2 PF13561.6 GAK66355.1 - 2.1e-27 96.2 0.0 1.3e-25 90.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK66355.1 - 1.7e-24 86.4 0.0 3.3e-24 85.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK66355.1 - 9.2e-05 22.4 0.1 0.00022 21.2 0.1 1.6 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAK66355.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pyrid_ox_like PF16242.5 GAK66356.1 - 6.2e-28 97.3 0.2 9.3e-28 96.7 0.2 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 GAK66356.1 - 2.3e-11 43.7 0.0 8.5e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GIT_SHD PF08518.11 GAK66357.1 - 3.5e-25 87.3 7.2 2.7e-14 52.5 1.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 GAK66357.1 - 0.00045 20.3 0.2 0.00045 20.3 0.2 3.2 4 0 0 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term ATG16 PF08614.11 GAK66357.1 - 0.0028 17.9 7.5 0.0028 17.9 7.5 4.7 4 1 0 4 4 4 2 Autophagy protein 16 (ATG16) MPS2 PF17060.5 GAK66357.1 - 0.23 10.7 7.4 0.54 9.5 7.4 1.6 1 0 0 1 1 1 0 Monopolar spindle protein 2 KxDL PF10241.9 GAK66357.1 - 0.43 10.9 21.2 0.059 13.7 2.2 4.5 3 1 0 3 3 3 0 Uncharacterized conserved protein YabA PF06156.13 GAK66357.1 - 0.45 11.2 16.2 4.1 8.1 4.7 3.6 3 0 0 3 3 3 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 GAK66357.1 - 0.56 10.3 17.8 1.4 9.0 0.7 4.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin PF00261.20 GAK66357.1 - 0.8 9.0 28.0 13 5.1 27.7 2.5 1 1 0 1 1 1 0 Tropomyosin NPV_P10 PF05531.12 GAK66357.1 - 0.93 10.0 12.0 0.12 12.9 0.5 4.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 GAK66357.1 - 1.9 8.3 16.9 0.13 12.0 5.8 2.9 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF4201 PF13870.6 GAK66357.1 - 2.1 8.1 21.8 0.62 9.8 7.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 GAK66357.1 - 6.4 5.6 36.0 0.019 13.9 23.2 3.2 3 1 0 3 3 3 0 Spc7 kinetochore protein Cnn_1N PF07989.11 GAK66357.1 - 7.2 6.9 17.0 0.95 9.7 3.8 4.2 2 1 1 4 4 4 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 GAK66357.1 - 7.4 5.6 23.0 8.9 5.3 1.6 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSNAXIP1_N PF15739.5 GAK66357.1 - 7.8 6.9 16.5 0.52 10.7 4.6 3.8 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus zf-C2H2 PF00096.26 GAK66358.1 - 1.8e-05 25.0 3.2 0.028 14.9 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK66358.1 - 4.3e-05 24.0 1.4 0.012 16.4 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF4207 PF13904.6 GAK66358.1 - 0.44 10.2 26.4 1.1 8.8 26.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) CDK5_activator PF03261.15 GAK66358.1 - 2.6 7.5 12.4 4.7 6.7 12.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein GREB1 PF15782.5 GAK66358.1 - 8.5 3.3 21.7 13 2.7 21.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Alpha-amylase_C PF02806.18 GAK66359.1 - 9.5e-26 90.1 0.1 3.6e-25 88.2 0.1 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 GAK66359.1 - 2.4e-16 59.8 0.0 5.4e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GAK66359.1 - 4.2e-13 49.6 0.1 1.2e-10 41.5 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GAK66359.1 - 0.0077 15.4 0.1 0.044 12.9 0.0 1.9 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain G-patch PF01585.23 GAK66361.1 - 1.7e-09 37.4 1.5 5.9e-09 35.7 1.5 2.0 1 0 0 1 1 1 1 G-patch domain SDA1 PF05285.12 GAK66361.1 - 2.2e-05 24.1 54.8 0.0024 17.4 24.9 2.3 2 0 0 2 2 2 2 SDA1 CDC45 PF02724.14 GAK66361.1 - 0.0077 14.6 49.6 0.093 11.0 25.6 2.3 2 0 0 2 2 2 2 CDC45-like protein G-patch_2 PF12656.7 GAK66361.1 - 0.019 15.0 0.9 0.019 15.0 0.9 4.4 4 1 0 4 4 4 0 G-patch domain YL1 PF05764.13 GAK66361.1 - 0.019 15.1 61.4 0.36 10.9 30.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein TFIIF_alpha PF05793.12 GAK66361.1 - 0.034 12.7 63.0 0.11 11.1 21.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BAF1_ABF1 PF04684.13 GAK66361.1 - 0.11 11.5 39.8 0.24 10.4 16.1 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF966 PF06136.13 GAK66361.1 - 0.18 11.5 40.2 0.058 13.1 19.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Apt1 PF10351.9 GAK66361.1 - 1.4 7.6 41.0 1.3 7.8 20.8 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain PPP4R2 PF09184.11 GAK66361.1 - 1.5 8.3 46.7 3 7.3 24.6 2.3 2 0 0 2 2 2 0 PPP4R2 WD40 PF00400.32 GAK66362.1 - 1.1e-08 35.5 13.8 0.00019 22.2 0.1 6.1 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 GAK66362.1 - 0.00024 21.4 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain G-alpha PF00503.20 GAK66363.1 - 3.9e-113 378.2 0.2 5e-113 377.9 0.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAK66363.1 - 3.7e-14 52.6 0.1 3e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAK66363.1 - 0.00036 20.0 0.1 0.69 9.2 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAK66363.1 - 0.046 13.9 0.2 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAK66363.1 - 0.14 12.6 0.0 4.7 7.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 GAK66363.1 - 0.19 11.5 0.0 0.52 10.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mito_carr PF00153.27 GAK66365.1 - 3.1e-56 187.3 3.0 1.7e-19 69.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RhoGEF PF00621.20 GAK66366.1 - 2.9e-33 115.6 0.0 6.2e-29 101.5 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain BAR PF03114.18 GAK66366.1 - 5.4e-07 29.5 1.2 9.2e-07 28.7 0.3 1.8 2 0 0 2 2 2 1 BAR domain Sugar_tr PF00083.24 GAK66367.1 - 1.8e-104 350.1 21.2 2.1e-104 349.9 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK66367.1 - 5.1e-32 111.2 26.2 1.2e-30 106.6 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAK66367.1 - 5.7e-07 28.3 2.9 5.7e-07 28.3 2.9 2.4 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 GAK66368.1 - 4e-81 272.8 0.0 6.1e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ADH_N PF08240.12 GAK66368.1 - 6.2e-28 96.9 2.9 1.2e-27 95.9 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK66368.1 - 1.3e-13 51.0 0.0 3.8e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding_C PF13193.6 GAK66368.1 - 6.3e-13 49.5 0.1 1.4e-12 48.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.12 GAK66369.1 - 5.9e-24 84.1 1.6 1e-23 83.3 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK66369.1 - 1e-15 57.9 0.0 2.4e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PDZ_6 PF17820.1 GAK66369.1 - 0.0036 17.1 0.7 0.009 15.8 0.2 1.9 2 0 0 2 2 2 1 PDZ domain 2-Hacid_dh_C PF02826.19 GAK66369.1 - 0.0042 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAK66369.1 - 0.0068 17.5 0.0 0.02 16.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PDZ_2 PF13180.6 GAK66369.1 - 0.044 14.1 1.2 0.29 11.5 0.1 2.8 3 2 2 5 5 5 0 PDZ domain PDZ PF00595.24 GAK66369.1 - 0.066 13.6 0.0 0.36 11.2 0.1 2.1 2 0 0 2 2 2 0 PDZ domain Far-17a_AIG1 PF04750.14 GAK66370.1 - 7.1e-32 110.4 1.3 1.1e-31 109.8 1.3 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Abhydrolase_6 PF12697.7 GAK66370.1 - 3.9e-13 50.5 2.8 1e-12 49.1 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 GAK66370.1 - 0.00025 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 GAK66370.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4992 PF16383.5 GAK66370.1 - 0.23 11.0 0.1 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function Sulfatase PF00884.23 GAK66371.1 - 3e-56 191.1 0.0 3.9e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 GAK66371.1 - 3.5e-25 87.6 2.2 8.3e-25 86.4 2.2 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 GAK66371.1 - 1.1e-08 35.1 0.0 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 GAK66371.1 - 0.012 14.3 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 GAK66371.1 - 0.013 16.2 0.1 0.039 14.7 0.1 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 GAK66371.1 - 0.038 13.9 0.0 4 7.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function TatD_DNase PF01026.21 GAK66372.1 - 1.6e-35 122.7 0.0 2.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DDT PF02791.17 GAK66372.1 - 0.16 12.3 1.5 8.9 6.7 0.0 3.2 3 0 0 3 3 3 0 DDT domain Sulfatase PF00884.23 GAK66373.1 - 1.1e-55 189.3 0.2 1.3e-55 189.0 0.2 1.1 1 0 0 1 1 1 1 Sulfatase DDE_5 PF13546.6 GAK66373.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Sial-lect-inser PF09264.10 GAK66373.1 - 0.054 13.3 0.0 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 Vibrio cholerae sialidase, lectin insertion Transferase PF02458.15 GAK66374.1 - 7.3e-22 77.6 0.0 1.9e-21 76.3 0.0 1.5 2 0 0 2 2 2 1 Transferase family DUF4267 PF14087.6 GAK66375.1 - 1.7e-25 89.2 3.8 2.1e-25 89.0 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DoxX_3 PF13781.6 GAK66375.1 - 0.37 11.5 5.8 0.2 12.3 3.1 1.9 2 1 0 2 2 2 0 DoxX-like family OTU PF02338.19 GAK66376.1 - 1.5e-10 41.7 0.0 3.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Zn_Tnp_IS1595 PF12760.7 GAK66376.1 - 0.1 12.6 2.5 0.27 11.2 2.5 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PAP_PilO PF06864.12 GAK66377.1 - 0.00018 20.4 0.2 0.00022 20.2 0.2 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) Trypan_PARP PF05887.11 GAK66377.1 - 0.0014 18.6 19.6 0.0014 18.6 19.6 1.5 2 0 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) DcuC PF03606.15 GAK66377.1 - 0.0015 17.1 0.8 0.0017 16.9 0.8 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier TMEM100 PF16311.5 GAK66377.1 - 0.0047 16.5 0.2 0.0059 16.2 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 100 TPR_21 PF09976.9 GAK66377.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF3262 PF11660.8 GAK66377.1 - 0.018 15.4 0.3 0.027 14.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) PgaD PF13994.6 GAK66377.1 - 0.025 14.6 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 PgaD-like protein Shisa PF13908.6 GAK66377.1 - 0.03 14.6 0.5 0.03 14.6 0.5 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 GAK66377.1 - 0.042 14.7 0.1 0.063 14.2 0.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GRIM-19 PF06212.12 GAK66377.1 - 0.095 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 GRIM-19 protein DUF4381 PF14316.6 GAK66377.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Vpu PF00558.19 GAK66377.1 - 0.14 12.0 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Vpu protein F-box PF00646.33 GAK66378.1 - 0.015 15.1 0.1 0.07 13.0 0.0 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 GAK66378.1 - 0.05 13.5 0.4 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 GAK66378.1 - 0.12 12.2 0.0 0.46 10.4 0.0 2.0 1 0 0 1 1 1 0 F-box FAD_binding_4 PF01565.23 GAK66382.1 - 2.8e-25 88.7 0.0 5.8e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GAK66382.1 - 5.3e-15 55.7 0.0 8.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Lipase_GDSL PF00657.22 GAK66382.1 - 0.13 12.3 0.0 0.7 9.8 0.0 2.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase RPE65 PF03055.15 GAK66383.1 - 3.2e-101 339.8 0.2 4e-101 339.5 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DEAD PF00270.29 GAK66384.1 - 4.1e-17 62.5 0.0 2.8e-16 59.8 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK66384.1 - 4.2e-15 56.1 0.0 1.8e-12 47.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAK66384.1 - 3.4e-12 46.9 1.9 9.8e-12 45.4 1.9 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 GAK66384.1 - 3.8e-05 23.8 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 GAK66384.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.6 GAK66384.1 - 0.094 13.0 0.8 1.9 8.8 0.2 3.0 2 1 0 2 2 2 0 AAA domain WCCH PF03716.14 GAK66384.1 - 0.14 11.9 0.4 0.34 10.6 0.4 1.6 1 0 0 1 1 1 0 WCCH motif SKA2 PF16740.5 GAK66384.1 - 0.88 9.4 3.4 17 5.2 0.3 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 mRNA_triPase PF02940.15 GAK66385.1 - 6.2e-55 186.3 0.3 7.4e-55 186.0 0.3 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain FAD_binding_4 PF01565.23 GAK66386.1 - 7.9e-23 80.7 0.9 1.3e-22 80.1 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAK66386.1 - 2.2e-09 37.2 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like ABC_membrane PF00664.23 GAK66387.1 - 2.4e-54 184.8 22.8 5.8e-34 118.0 7.3 3.8 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK66387.1 - 4.4e-49 166.5 0.1 5.2e-29 101.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAK66387.1 - 6.3e-09 35.6 4.2 0.015 14.7 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 GAK66387.1 - 4.6e-08 33.4 0.3 0.0033 17.6 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 GAK66387.1 - 5.4e-07 29.2 0.4 0.006 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAK66387.1 - 3.3e-06 27.8 0.0 0.0026 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 GAK66387.1 - 8.6e-06 24.9 0.0 0.095 11.6 0.0 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 GAK66387.1 - 7.6e-05 22.8 0.0 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAK66387.1 - 0.0002 21.8 17.5 0.00094 19.6 0.1 4.7 4 3 0 4 4 4 2 AAA ATPase domain AAA_30 PF13604.6 GAK66387.1 - 0.00025 20.8 0.4 0.11 12.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 GAK66387.1 - 0.00026 20.9 7.9 0.14 11.9 0.0 3.7 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAK66387.1 - 0.00039 20.7 0.7 2.6 8.3 0.0 4.0 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 GAK66387.1 - 0.00087 19.2 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 GAK66387.1 - 0.0038 17.0 0.1 5.3 6.7 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein CbiA PF01656.23 GAK66387.1 - 0.004 17.2 0.0 0.074 13.1 0.0 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 GAK66387.1 - 0.0043 16.7 0.0 0.95 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAK66387.1 - 0.0046 16.9 0.8 2.8 7.8 0.0 3.2 3 0 0 3 3 2 1 NACHT domain T2SSE PF00437.20 GAK66387.1 - 0.0098 15.0 0.0 0.26 10.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.29 GAK66387.1 - 0.011 15.5 0.0 25 4.6 0.0 4.0 4 0 0 4 4 4 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 GAK66387.1 - 0.014 15.6 1.8 0.2 11.9 0.3 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.7 GAK66387.1 - 0.02 13.9 1.5 0.3 10.0 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain UPF0114 PF03350.16 GAK66387.1 - 0.021 15.0 0.4 0.34 11.1 0.0 3.0 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 AAA PF00004.29 GAK66387.1 - 0.021 15.3 0.1 15 6.0 0.0 3.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 GAK66387.1 - 0.027 14.5 2.1 0.94 9.5 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 GAK66387.1 - 0.028 13.9 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 GAK66387.1 - 0.032 13.4 0.0 7 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 GAK66387.1 - 0.033 13.9 0.1 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 GAK66387.1 - 0.034 14.6 0.1 17 5.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 GAK66387.1 - 0.037 13.8 0.1 2.7 7.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 GAK66387.1 - 0.037 14.2 0.2 20 5.5 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 GAK66387.1 - 0.057 12.8 0.1 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_27 PF13514.6 GAK66387.1 - 0.07 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytochrom_B_N_2 PF13631.6 GAK66387.1 - 0.11 12.5 1.9 0.17 11.9 0.0 2.4 2 0 0 2 2 1 0 Cytochrome b(N-terminal)/b6/petB AAA_5 PF07728.14 GAK66387.1 - 0.11 12.4 0.1 31 4.5 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAK66387.1 - 0.12 12.0 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAK66387.1 - 0.13 12.8 0.0 38 4.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 GAK66387.1 - 0.13 11.8 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 GAK66387.1 - 0.17 11.7 0.5 1.1e+02 2.5 0.1 3.5 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 GAK66387.1 - 0.33 11.1 3.7 19 5.4 0.7 3.7 3 1 0 3 3 2 0 AAA domain KH_6 PF15985.5 GAK66388.1 - 2.9e-12 46.7 0.0 6.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 GAK66388.1 - 8e-06 25.6 0.0 2e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region DUF5586 PF17824.1 GAK66388.1 - 0.055 12.6 0.1 0.073 12.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5586) Myb_DNA-bind_2 PF08914.11 GAK66389.1 - 2.5e-05 24.4 3.7 0.0021 18.2 0.1 2.9 2 1 0 2 2 2 2 Rap1 Myb domain BRCT_2 PF16589.5 GAK66389.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 GAK66389.1 - 9.2 6.9 10.9 0.22 12.1 1.3 3.0 2 1 0 2 2 2 0 Rap1, DNA-binding Shugoshin_C PF07557.11 GAK66390.1 - 3e-07 30.1 3.4 3e-07 30.1 3.4 2.8 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.11 GAK66390.1 - 5.6e-07 29.3 1.5 1.1e-06 28.4 1.5 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Rab5ip PF07019.12 GAK66391.1 - 2e-16 60.3 5.3 4e-16 59.4 5.3 1.5 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3099 PF11298.8 GAK66391.1 - 0.063 13.4 1.5 0.14 12.3 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) RRM_1 PF00076.22 GAK66392.1 - 9.9e-34 115.0 0.0 4.2e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 GAK66392.1 - 3.6e-05 24.1 0.1 0.35 11.1 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 GAK66392.1 - 7.7e-05 22.7 0.0 0.00056 20.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 GAK66392.1 - 0.00017 21.1 0.0 0.16 11.6 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAK66392.1 - 0.0006 19.8 0.1 0.16 12.0 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.11 GAK66392.1 - 0.061 13.0 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain MFS_1 PF07690.16 GAK66393.1 - 1.3e-23 83.5 46.2 1.3e-23 83.5 46.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_M PF01004.19 GAK66393.1 - 0.14 11.9 0.7 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M DUF829 PF05705.14 GAK66394.1 - 3.8e-24 85.9 0.0 2e-17 63.9 0.0 3.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Hydrolase_6 PF13344.6 GAK66395.1 - 3.2e-22 78.5 0.0 5.5e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAK66395.1 - 2.2e-19 69.3 0.0 4.6e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2142 PF09913.9 GAK66396.1 - 0.34 9.7 0.2 0.51 9.1 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Esterase_phd PF10503.9 GAK66402.1 - 3e-15 56.3 0.4 5.8e-15 55.4 0.4 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAK66402.1 - 1.8e-13 50.5 1.5 3e-13 49.8 1.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 GAK66402.1 - 0.00087 19.0 0.3 0.0016 18.1 0.3 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 GAK66402.1 - 0.0052 16.1 0.2 0.25 10.6 0.1 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAK66402.1 - 0.087 12.6 0.1 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF4690 PF15756.5 GAK66404.1 - 2.7 8.7 4.2 9.3 6.9 0.7 2.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Pkinase PF00069.25 GAK66405.1 - 4e-37 128.0 0.0 8.8e-37 126.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66405.1 - 1.9e-12 47.1 0.0 2.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.10 GAK66405.1 - 2e-06 26.6 0.0 0.00036 19.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.23 GAK66405.1 - 1.9e-05 24.7 0.1 1.9e-05 24.7 0.1 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAK66405.1 - 0.0045 16.6 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 GAK66405.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_A_M PF01068.21 GAK66406.1 - 3e-36 125.0 0.1 3.1e-27 95.6 0.0 3.5 3 0 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAK66406.1 - 2.1e-33 116.1 0.0 3.9e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAK66406.1 - 4.1e-18 65.8 0.0 1.1e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region ParA PF10609.9 GAK66407.1 - 1.2e-75 254.2 0.0 3.4e-75 252.7 0.0 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAK66407.1 - 1e-09 38.6 0.0 4e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAK66407.1 - 1e-06 28.8 0.0 9.4e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 GAK66407.1 - 5.3e-05 22.5 1.9 0.00024 20.4 0.3 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 GAK66407.1 - 5.6e-05 23.1 0.2 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 GAK66407.1 - 0.0002 20.7 0.2 0.0011 18.3 0.0 2.0 1 1 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 GAK66407.1 - 0.00041 20.0 0.0 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 GAK66407.1 - 0.0016 17.9 0.1 0.031 13.7 0.0 2.2 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DHDPS PF00701.22 GAK66408.1 - 1.7e-40 138.6 0.0 1.9e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family 4HBT PF03061.22 GAK66409.1 - 4.5e-11 42.9 0.2 9.9e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 GAK66409.1 - 0.0042 17.2 0.1 0.0053 16.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) HA2 PF04408.23 GAK66410.1 - 2.3e-22 79.3 0.0 2.3e-22 79.3 0.0 4.3 7 0 0 7 7 7 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAK66410.1 - 2.9e-11 43.7 0.2 1e-09 38.7 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAK66410.1 - 1.1e-10 41.7 0.0 2.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAK66410.1 - 6.7e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK66410.1 - 6.9e-06 26.4 0.0 3.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAK66410.1 - 0.00096 19.5 0.2 0.0087 16.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 GAK66410.1 - 0.021 15.4 0.0 0.021 15.4 0.0 3.0 4 0 0 4 4 4 0 AAA domain ATPase PF06745.13 GAK66410.1 - 0.024 14.0 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2951 PF11166.8 GAK66411.1 - 2.2 8.5 5.3 5.6 7.3 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Ribosomal_S19e PF01090.19 GAK66412.1 - 4.8e-56 188.2 0.0 6.4e-56 187.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19e TANGO2 PF05742.12 GAK66413.1 - 2.3e-59 201.5 0.0 2.7e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 TFIIS_C PF01096.18 GAK66414.1 - 9.2e-11 41.4 0.2 9.2e-11 41.4 0.2 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAK66414.1 - 9.5e-10 38.2 2.5 9.5e-10 38.2 2.5 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 GAK66414.1 - 0.13 12.2 4.8 4.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 GAK66414.1 - 0.28 11.2 6.5 2.8 8.0 0.0 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Auto_anti-p27 PF06677.12 GAK66414.1 - 1.2 9.4 6.2 11 6.2 2.5 2.6 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PHD PF00628.29 GAK66414.1 - 1.7 8.6 8.6 0.41 10.6 3.9 2.2 2 1 0 2 2 2 0 PHD-finger DUF3716 PF12511.8 GAK66414.1 - 3.8 7.6 7.7 47 4.1 4.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) FGGY_N PF00370.21 GAK66415.1 - 1.3e-72 244.3 0.4 1.8e-72 243.8 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAK66415.1 - 2.1e-64 216.9 1.4 1.3e-63 214.3 1.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain AAA PF00004.29 GAK66416.1 - 1.7e-49 167.6 0.0 4.2e-41 140.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 GAK66416.1 - 1.4e-33 114.4 26.6 1.3e-08 35.3 0.9 8.5 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66416.1 - 1.7e-13 50.7 0.2 0.00039 20.7 0.0 5.3 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_lid_3 PF17862.1 GAK66416.1 - 4.7e-09 35.9 0.6 1.8e-08 34.0 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 GAK66416.1 - 3.6e-07 30.7 4.2 9.7e-05 22.8 0.0 4.0 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 GAK66416.1 - 3.5e-05 23.6 0.0 7.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 GAK66416.1 - 7.7e-05 22.9 0.0 0.00029 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAK66416.1 - 0.0003 21.0 2.6 0.1 12.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain Ge1_WD40 PF16529.5 GAK66416.1 - 0.00034 19.7 0.1 0.34 9.8 0.0 3.4 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_5 PF07728.14 GAK66416.1 - 0.0015 18.5 0.0 0.01 15.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAK66416.1 - 0.0087 16.6 0.0 0.076 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAK66416.1 - 0.012 15.8 0.3 0.32 11.3 0.0 3.2 3 1 1 4 4 4 0 AAA domain AFG1_ATPase PF03969.16 GAK66416.1 - 0.023 13.6 0.5 1.4 7.8 0.0 2.6 3 0 0 3 3 3 0 AFG1-like ATPase DUF2075 PF09848.9 GAK66416.1 - 0.058 12.6 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 GAK66416.1 - 0.078 13.1 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 GAK66416.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 GAK66416.1 - 0.12 12.1 0.0 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain TIP49 PF06068.13 GAK66416.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 GAK66416.1 - 0.13 11.8 0.0 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Bromodomain PF00439.25 GAK66416.1 - 0.13 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Bromodomain ResIII PF04851.15 GAK66416.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CRAL_TRIO_2 PF13716.6 GAK66418.1 - 5.3e-33 114.1 0.0 8.9e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 GAK66418.1 - 6.1e-25 87.8 0.0 1.3e-24 86.7 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.16 GAK66419.1 - 3.2e-19 69.1 41.0 3.2e-19 69.1 41.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK66419.1 - 0.0002 20.4 9.6 0.0002 20.4 9.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter LRR_9 PF14580.6 GAK66420.1 - 3.3e-58 196.0 0.4 4.7e-58 195.5 0.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GAK66420.1 - 3.6e-12 46.3 10.2 2.3e-08 34.2 0.7 3.5 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAK66420.1 - 3.4e-09 36.3 5.0 1.7e-08 34.1 3.3 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 GAK66420.1 - 0.98 10.2 4.6 30 5.7 0.2 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GAK66420.1 - 1 9.6 6.3 1.2e+02 3.1 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat Suc_Fer-like PF06999.12 GAK66421.1 - 1.3e-24 87.2 0.0 2.4e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like LIAS_N PF16881.5 GAK66421.1 - 1.8e-20 73.4 0.0 4.9e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 GAK66421.1 - 8.2e-12 45.8 0.0 1.4e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Dynein_light PF01221.18 GAK66423.1 - 2.8e-35 120.5 0.2 3.3e-35 120.3 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 GAK66423.1 - 0.032 14.0 0.1 0.043 13.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 48 DUF1992 PF09350.10 GAK66424.1 - 4.8e-21 74.7 2.0 1.8e-20 72.9 0.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1992) Glyco_trans_4_4 PF13579.6 GAK66425.1 - 1e-10 42.3 10.9 1e-10 42.3 10.9 2.9 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 GAK66425.1 - 4.1e-07 30.5 0.0 1.8e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAK66425.1 - 4.7e-05 23.4 3.8 9.4e-05 22.5 3.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 GAK66425.1 - 0.00095 19.5 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAK66425.1 - 0.0097 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 GAK66425.1 - 0.027 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like Prefoldin_2 PF01920.20 GAK66426.1 - 1.5e-18 66.7 4.3 1.9e-18 66.3 4.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 GAK66426.1 - 0.00065 19.6 2.2 0.00098 19.0 2.1 1.4 1 1 0 1 1 1 1 Prefoldin subunit GvpK PF05121.12 GAK66426.1 - 0.002 18.2 0.7 0.002 18.2 0.7 2.1 1 1 2 3 3 3 1 Gas vesicle protein K PI3K_P85_iSH2 PF16454.5 GAK66426.1 - 0.0045 16.6 3.6 0.027 14.0 3.4 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5064 PF16703.5 GAK66426.1 - 0.046 14.2 0.5 0.29 11.6 0.1 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5064) XhlA PF10779.9 GAK66426.1 - 1.6 9.0 4.5 0.46 10.7 0.7 1.9 2 1 0 2 2 2 0 Haemolysin XhlA Apt1 PF10351.9 GAK66427.1 - 1.9 7.2 5.1 3.5 6.4 5.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain YL1_C PF08265.11 GAK66429.1 - 2.1e-14 52.9 0.4 2.1e-14 52.9 0.4 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Trypan_PARP PF05887.11 GAK66429.1 - 0.066 13.2 9.0 0.1 12.6 9.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Adeno_terminal PF02459.15 GAK66429.1 - 0.12 10.7 5.3 0.14 10.5 5.3 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Spore_coat_CotO PF14153.6 GAK66429.1 - 0.15 12.0 9.8 0.18 11.7 9.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 GAK66429.1 - 0.92 8.2 7.5 1 8.0 7.5 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 GAK66429.1 - 1.9 7.8 19.4 2.3 7.5 19.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PI-PLC-X PF00388.19 GAK66430.1 - 9.2e-08 31.8 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain TraK PF06586.11 GAK66430.1 - 0.015 15.0 0.2 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 TraK protein SDA1 PF05285.12 GAK66432.1 - 0.074 12.5 2.5 0.093 12.1 2.5 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAK66432.1 - 4.3 5.4 5.8 5.4 5.1 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_S10 PF00450.22 GAK66433.1 - 4.2e-105 352.6 0.0 5e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PRCC PF10253.9 GAK66434.1 - 1.8e-15 58.3 7.1 1.8e-15 58.3 7.1 3.5 2 2 0 3 3 3 2 Mitotic checkpoint regulator, MAD2B-interacting Foie-gras_1 PF11817.8 GAK66435.1 - 7.2e-27 94.6 0.0 2.4e-25 89.6 0.0 3.0 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 GAK66435.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi ALGX PF16822.5 GAK66435.1 - 0.024 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX TPR_20 PF14561.6 GAK66435.1 - 1 9.8 3.4 29 5.1 0.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 GAK66437.1 - 9e-07 28.9 6.1 0.001 19.2 0.8 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain TB2_DP1_HVA22 PF03134.19 GAK66438.1 - 2.2e-25 88.4 11.1 3.4e-25 87.8 11.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 GAK66438.1 - 0.0088 16.3 0.4 0.014 15.6 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2304) UPF0227 PF05728.12 GAK66438.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) COesterase PF00135.28 GAK66439.1 - 6.2e-86 289.3 0.0 8.3e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK66439.1 - 4.7e-06 26.6 0.5 0.0004 20.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAK66439.1 - 0.011 15.2 0.1 0.034 13.6 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family EAP30 PF04157.16 GAK66440.1 - 9.7e-66 221.4 0.0 1.1e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DER1 PF04511.15 GAK66441.1 - 0.029 14.3 3.1 0.051 13.5 3.1 1.3 1 0 0 1 1 1 0 Der1-like family Rhomboid PF01694.22 GAK66441.1 - 0.08 12.9 8.6 0.6 10.1 8.6 2.1 1 1 0 1 1 1 0 Rhomboid family DUF1751 PF08551.10 GAK66441.1 - 0.083 13.5 1.5 0.13 12.8 0.3 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) TPP1 PF10341.9 GAK66442.1 - 1.3e-07 31.6 0.0 3.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD MCM3AP_GANP PF16769.5 GAK66442.1 - 0.88 7.7 4.8 0.96 7.6 4.2 1.3 1 1 0 1 1 1 0 MCM3AP domain of GANP PE_PPE_C PF12484.8 GAK66442.1 - 6.6 7.7 11.3 0.5 11.3 0.9 2.6 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Ribosomal_L15e PF00827.17 GAK66443.1 - 3.2e-82 274.9 13.2 5.1e-76 254.7 11.1 2.4 2 0 0 2 2 2 2 Ribosomal L15 UBA_6 PF18039.1 GAK66443.1 - 0.18 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Ribosomal_L5e PF17144.4 GAK66444.1 - 6.9e-80 266.8 0.1 1.1e-79 266.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAK66444.1 - 9.3e-32 109.8 3.8 9.3e-32 109.8 3.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 GAK66444.1 - 0.011 16.1 0.9 0.022 15.1 0.1 1.8 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF5388 PF17363.2 GAK66444.1 - 0.034 14.3 0.0 0.45 10.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5388) DUF5104 PF17117.5 GAK66444.1 - 0.049 14.1 0.9 0.096 13.1 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) Spore_III_AB PF09548.10 GAK66444.1 - 0.072 13.2 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) EDS1_EP PF18117.1 GAK66444.1 - 0.075 13.5 0.6 0.075 13.5 0.6 2.0 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain Ribosomal_S19 PF00203.21 GAK66445.1 - 9.8e-30 102.3 0.2 1.5e-29 101.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 ALC PF17527.2 GAK66445.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage ALC protein Ribosomal_60s PF00428.19 GAK66446.1 - 2.1e-27 95.5 15.0 3e-27 95.0 15.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 GAK66446.1 - 0.15 12.8 5.3 0.21 12.3 5.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cytochrom_C1 PF02167.15 GAK66447.1 - 3.9e-97 324.3 0.0 5.2e-97 323.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAK66447.1 - 0.0018 18.6 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 GAK66447.1 - 0.083 14.0 0.2 0.3 12.2 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c ERCC4 PF02732.15 GAK66448.1 - 2.2e-22 79.9 0.0 3.8e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 GAK66448.1 - 0.00026 21.3 0.0 0.00096 19.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ACC_central PF08326.12 GAK66449.1 - 3.4e-207 690.1 0.0 4.8e-207 689.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 GAK66449.1 - 1.3e-176 588.1 0.0 1.7e-176 587.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAK66449.1 - 2.2e-53 180.9 0.0 5.1e-53 179.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAK66449.1 - 2.3e-28 99.0 0.1 6e-28 97.6 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAK66449.1 - 6.1e-21 74.5 0.0 1.2e-19 70.4 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAK66449.1 - 1.5e-14 53.6 0.2 3.1e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAK66449.1 - 3.6e-06 26.7 0.0 1.5e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAK66449.1 - 0.0011 18.6 0.0 0.0035 16.9 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAK66449.1 - 0.0014 18.2 0.1 0.0041 16.7 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAK66449.1 - 0.0074 16.3 0.0 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.6 GAK66449.1 - 0.018 15.0 0.5 0.059 13.3 0.1 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain TFIIB_C_1 PF18542.1 GAK66449.1 - 0.11 12.6 1.0 0.64 10.1 1.0 2.4 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Scm3 PF10384.9 GAK66450.1 - 5.7e-15 54.8 0.2 5.7e-15 54.8 0.2 2.6 3 0 0 3 3 3 1 Centromere protein Scm3 DUF2280 PF10045.9 GAK66450.1 - 0.15 12.3 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) DUF1746 PF08508.10 GAK66451.1 - 5.5e-24 84.7 2.7 8.7e-24 84.1 2.7 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Ribosomal_L35Ae PF01247.18 GAK66452.1 - 7.5e-42 141.4 2.2 1.2e-41 140.8 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae zf-C2H2_jaz PF12171.8 GAK66453.1 - 3.4e-09 36.7 0.5 5.2e-09 36.1 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAK66453.1 - 0.0063 16.8 0.0 0.0063 16.8 0.0 1.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAK66453.1 - 0.011 16.1 0.2 0.018 15.5 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAK66453.1 - 0.024 15.1 0.4 0.024 15.1 0.4 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK66453.1 - 0.11 13.4 0.1 0.11 13.4 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Nucleopor_Nup85 PF07575.13 GAK66454.1 - 5.5e-87 292.7 0.0 3e-52 178.0 0.1 2.5 2 1 0 2 2 2 2 Nup85 Nucleoporin Rep_fac_C PF08542.11 GAK66455.1 - 4.3e-21 75.1 0.0 9e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GAK66455.1 - 5.3e-17 62.5 0.0 1.1e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAK66455.1 - 2e-15 57.0 0.0 7.6e-11 42.1 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 GAK66455.1 - 9.8e-10 38.6 0.0 2.9e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 GAK66455.1 - 1.2e-05 25.2 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAK66455.1 - 1.8e-05 24.0 0.0 2.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 GAK66455.1 - 2.1e-05 24.3 0.0 8.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAK66455.1 - 5e-05 23.2 0.1 0.0003 20.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 GAK66455.1 - 8.3e-05 22.8 0.2 0.00037 20.8 0.0 2.2 3 0 0 3 3 1 1 AAA C-terminal domain RuvB_N PF05496.12 GAK66455.1 - 9.6e-05 22.2 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAK66455.1 - 0.00014 21.9 0.1 0.0015 18.5 0.0 2.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAK66455.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 GAK66455.1 - 0.00017 21.9 0.1 0.031 14.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAK66455.1 - 0.00022 21.7 0.0 0.00049 20.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 GAK66455.1 - 0.00056 19.9 0.0 0.002 18.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain WGG PF10273.9 GAK66455.1 - 0.0025 18.4 0.0 0.058 14.1 0.0 2.4 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 ResIII PF04851.15 GAK66455.1 - 0.006 16.6 0.0 0.052 13.5 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAK66455.1 - 0.0078 16.6 0.1 0.037 14.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 GAK66455.1 - 0.012 15.1 0.0 0.27 10.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 GAK66455.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAK66455.1 - 0.019 14.1 0.0 0.046 12.8 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DNA_pol3_delta PF06144.13 GAK66455.1 - 0.02 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.29 GAK66455.1 - 0.035 13.9 0.1 0.26 11.0 0.1 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase MCM PF00493.23 GAK66455.1 - 0.047 12.8 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain IstB_IS21 PF01695.17 GAK66455.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 GAK66455.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAK66455.1 - 0.056 12.8 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 GAK66455.1 - 0.059 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 GAK66455.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAK66455.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase A_deaminase PF00962.22 GAK66456.1 - 1.2e-121 406.0 0.1 1.7e-121 405.5 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DASH_Spc34 PF08657.10 GAK66457.1 - 0.0001 22.2 0.0 0.074 12.8 0.0 2.7 2 0 0 2 2 2 2 DASH complex subunit Spc34 DUF4407 PF14362.6 GAK66457.1 - 0.41 10.0 10.4 0.31 10.4 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cyt-b5 PF00173.28 GAK66458.1 - 8.4e-20 70.7 0.0 1.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.19 GAK66459.1 - 6.2e-31 107.1 0.2 1.5e-30 105.9 0.2 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 GAK66459.1 - 3.8e-16 58.4 0.0 9.6e-16 57.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAK66459.1 - 2.5e-15 56.1 0.1 4.7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAK66459.1 - 2.4e-11 43.1 0.0 6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 GAK66459.1 - 7.6e-09 35.8 1.8 1.3e-08 35.0 0.6 2.0 2 0 0 2 2 2 1 GAT domain Hrs_helical PF12210.8 GAK66459.1 - 0.001 19.6 0.6 0.001 19.6 0.6 2.1 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.20 GAK66459.1 - 0.015 15.2 3.8 0.015 15.2 3.8 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif SAPS PF04499.15 GAK66459.1 - 3 6.5 6.7 6.8 5.4 6.7 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.13 GAK66459.1 - 4.6 7.1 33.4 0.1 12.6 12.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2183 PF09949.9 GAK66460.1 - 8.8e-24 83.7 0.0 5.7e-23 81.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 GAK66460.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) MTHFR PF02219.17 GAK66461.1 - 1.8e-111 372.1 0.0 2.8e-111 371.4 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Skp1 PF01466.19 GAK66462.1 - 1.2e-25 89.3 0.1 2.3e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAK66462.1 - 2.1e-25 88.7 0.1 5.1e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Zn_clus PF00172.18 GAK66462.1 - 1.4e-05 25.1 10.4 2.8e-05 24.2 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAP65_ASE1 PF03999.12 GAK66462.1 - 0.88 8.2 4.3 1.5 7.4 4.3 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF908 PF06012.12 GAK66462.1 - 2.8 7.3 6.6 1.4 8.3 4.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Paf1 PF03985.13 GAK66463.1 - 3e-55 187.9 14.3 3.5e-53 181.1 10.4 3.6 1 1 1 2 2 2 1 Paf1 PseudoU_synth_1 PF01416.20 GAK66464.1 - 2e-22 79.7 0.1 2.9e-19 69.5 0.0 3.3 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF1771 PF08590.10 GAK66464.1 - 1.4e-13 50.9 4.6 5.5e-13 49.1 4.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) HBS1_N PF08938.10 GAK66464.1 - 0.0033 17.7 0.0 0.0075 16.6 0.0 1.5 1 0 0 1 1 1 1 HBS1 N-terminus zf-CCCH_3 PF15663.5 GAK66464.1 - 0.042 14.1 6.7 0.21 11.8 6.7 2.0 1 1 0 1 1 1 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 GAK66464.1 - 0.042 13.6 17.0 0.03 14.1 3.6 3.0 2 1 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAK66464.1 - 0.12 12.4 13.2 0.87 9.7 1.6 3.0 2 1 0 2 2 2 0 Zinc finger domain LUC7 PF03194.15 GAK66464.1 - 0.54 9.9 2.5 2 8.0 0.1 2.7 3 1 1 4 4 4 0 LUC7 N_terminus tRNA-synt_2 PF00152.20 GAK66465.1 - 2.6e-72 243.6 0.0 3.5e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Neugrin PF06413.11 GAK66465.1 - 2.1e-09 37.7 0.4 4.4e-09 36.7 0.4 1.5 1 0 0 1 1 1 1 Neugrin RsfS PF02410.15 GAK66465.1 - 3.7e-07 30.5 0.0 1.7e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation tRNA_anti-codon PF01336.25 GAK66465.1 - 7.7e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MRP-L20 PF12824.7 GAK66465.1 - 0.011 15.9 2.9 0.017 15.3 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 NADH-u_ox-rdase PF10785.9 GAK66466.1 - 2.3e-32 111.5 0.2 3.9e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 GAK66466.1 - 2.4e-12 46.6 0.1 4.2e-12 45.9 0.1 1.4 1 1 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TPR_2 PF07719.17 GAK66467.1 - 1.9e-09 36.9 3.7 1.1e-05 25.2 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAK66467.1 - 5.2e-08 32.4 2.1 0.00013 21.7 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK66467.1 - 3.1e-05 24.4 2.5 0.0029 18.3 0.3 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAK66467.1 - 0.00014 21.9 0.6 0.0071 16.5 0.0 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAK66467.1 - 0.00057 20.5 0.9 1.3 9.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAK66467.1 - 0.0035 17.5 0.1 0.088 13.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAK66467.1 - 0.02 15.2 0.7 0.77 10.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAK66467.1 - 0.028 14.1 0.1 0.66 9.7 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 GAK66467.1 - 0.062 14.0 0.5 19 6.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.20 GAK66468.1 - 4.4e-55 185.5 1.3 5.2e-55 185.3 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 GAK66468.1 - 0.064 12.8 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain TPR_14 PF13428.6 GAK66469.1 - 4.8e-05 23.8 11.7 0.03 15.1 0.3 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK66469.1 - 0.00016 22.1 9.9 0.0032 17.9 2.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat LppC PF04348.13 GAK66469.1 - 0.011 14.6 0.9 0.017 14.0 0.9 1.3 1 0 0 1 1 1 0 LppC putative lipoprotein TPR_2 PF07719.17 GAK66469.1 - 0.014 15.5 3.5 0.86 9.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAK66469.1 - 0.02 15.5 1.2 0.02 15.5 1.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAK66469.1 - 0.077 13.7 0.8 0.077 13.7 0.8 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAK66469.1 - 0.084 12.3 0.4 0.21 11.0 0.3 1.6 1 1 0 1 1 1 0 Coatomer epsilon subunit DUF2007 PF09413.10 GAK66469.1 - 0.15 12.2 1.6 0.31 11.2 0.7 2.1 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein TPR_12 PF13424.6 GAK66469.1 - 0.16 12.3 5.7 0.61 10.4 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1843 PF08898.10 GAK66469.1 - 0.19 12.3 3.1 0.25 11.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) TPR_7 PF13176.6 GAK66469.1 - 0.22 11.6 3.2 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Actin PF00022.19 GAK66470.1 - 1.3e-22 80.0 0.0 4.8e-12 45.2 0.0 3.2 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 GAK66470.1 - 1.3e-05 24.6 0.0 0.054 12.7 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family AA_permease PF00324.21 GAK66471.1 - 4.6e-65 220.1 30.1 5.8e-65 219.7 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 GAK66471.1 - 2.5e-19 69.6 0.3 5.7e-11 42.1 0.0 3.4 3 0 0 3 3 3 3 Solute carrier family 12 Cwf_Cwc_15 PF04889.12 GAK66471.1 - 0.97 9.1 6.7 0.67 9.6 2.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 GAK66472.1 - 0.2 9.4 1.3 0.24 9.1 1.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ctr PF04145.15 GAK66473.1 - 1.5e-05 25.7 12.1 0.017 15.8 0.3 2.1 1 1 1 2 2 2 2 Ctr copper transporter family PRP38 PF03371.15 GAK66474.1 - 5.2e-53 179.5 0.0 6.4e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF4196 PF13846.6 GAK66474.1 - 1.9 8.7 5.5 23 5.2 6.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4196) WD40 PF00400.32 GAK66475.1 - 4e-14 52.8 6.2 0.039 14.8 0.0 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66475.1 - 0.044 14.1 0.0 0.31 11.4 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ABC_transp_aux PF09822.9 GAK66475.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system PilO PF04350.13 GAK66475.1 - 6.1 7.0 7.3 3.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Pilus assembly protein, PilO GHMP_kinases_N PF00288.26 GAK66476.1 - 1.8e-10 40.9 0.1 4.8e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAK66476.1 - 0.0001 22.6 0.0 0.00032 21.0 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal SAC3_GANP PF03399.16 GAK66477.1 - 1.4e-20 73.9 3.9 1.6e-18 67.1 3.9 2.4 1 1 0 1 1 1 1 SAC3/GANP family BAG PF02179.16 GAK66477.1 - 2.2e-14 53.7 3.6 6.8e-14 52.1 3.6 2.0 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 GAK66477.1 - 2e-05 24.3 0.0 5.9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family COX5A PF02284.16 GAK66477.1 - 0.0061 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va CSN8_PSD8_EIF3K PF10075.9 GAK66477.1 - 0.01 15.8 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family DUF982 PF06169.12 GAK66477.1 - 0.061 13.4 0.3 15 5.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF982) Holin_BhlA PF10960.8 GAK66477.1 - 0.13 12.2 2.5 1.1 9.3 0.5 2.6 2 0 0 2 2 2 0 BhlA holin family Pkinase PF00069.25 GAK66478.1 - 2.1e-52 178.1 0.0 2.9e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66478.1 - 2.4e-19 69.6 0.0 3.9e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK66478.1 - 0.0096 15.9 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAK66478.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Tim44 PF04280.15 GAK66479.1 - 6e-33 114.0 0.8 2.9e-32 111.8 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain SUIM_assoc PF16619.5 GAK66479.1 - 0.13 12.3 5.0 0.71 10.0 4.5 2.4 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 GAK66479.1 - 0.23 10.5 7.8 0.41 9.7 7.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Mitoc_mL59 PF18126.1 GAK66480.1 - 1.2e-28 100.0 2.1 1.5e-28 99.6 2.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 DUF3446 PF11928.8 GAK66480.1 - 0.029 14.7 12.7 0.029 14.7 12.7 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain PHD20L1_u1 PF16660.5 GAK66480.1 - 0.043 14.5 4.9 0.09 13.5 4.9 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 Q_salvage PF10343.9 GAK66481.1 - 8.8e-06 25.5 0.0 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Zn_clus PF00172.18 GAK66482.1 - 2.3e-06 27.6 8.7 4.9e-06 26.5 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK66482.1 - 0.024 13.6 0.0 0.058 12.4 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain INO80_Ies4 PF08193.11 GAK66482.1 - 6.1 6.8 11.6 1.2 9.1 1.5 2.4 2 0 0 2 2 2 0 INO80 complex subunit Ies4 UCH_1 PF13423.6 GAK66483.1 - 3.4e-91 306.2 0.0 4.6e-91 305.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 GAK66483.1 - 3.7e-19 69.9 0.0 5.3e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 Exonuclease WD40 PF00400.32 GAK66483.1 - 0.0023 18.7 0.1 0.07 14.0 0.0 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat UCH PF00443.29 GAK66483.1 - 0.043 13.3 0.0 0.4 10.1 0.0 2.2 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PPP4R2 PF09184.11 GAK66483.1 - 0.38 10.3 12.3 0.71 9.4 12.3 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4647 PF15504.6 GAK66483.1 - 4.8 6.2 8.9 7.1 5.6 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CDP-OH_P_transf PF01066.21 GAK66484.1 - 2.6e-13 50.5 0.2 6.5e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Med4 PF10018.9 GAK66486.1 - 1.5e-18 67.2 8.6 2.8e-18 66.3 8.6 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 APG6_N PF17675.1 GAK66486.1 - 0.64 10.5 6.2 0.24 11.9 2.9 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region ubiquitin PF00240.23 GAK66487.1 - 2.2e-34 117.0 0.5 3.4e-34 116.4 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 GAK66487.1 - 7.5e-25 86.8 1.1 1.5e-24 85.9 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GAK66487.1 - 3.9e-16 58.6 0.6 7.9e-16 57.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAK66487.1 - 3.3e-05 24.2 0.1 0.00014 22.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAK66487.1 - 0.0011 19.1 0.2 0.0025 17.9 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 GAK66487.1 - 0.0044 17.2 0.4 0.0072 16.5 0.4 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Ubiquitin_5 PF18037.1 GAK66487.1 - 0.0062 16.9 0.2 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAK66487.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GAK66487.1 - 0.018 15.6 0.4 0.025 15.1 0.4 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAK66487.1 - 0.024 14.7 1.1 5.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DEAD PF00270.29 GAK66488.1 - 6.2e-44 149.9 0.0 3.7e-43 147.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK66488.1 - 4.6e-27 94.5 0.0 5e-26 91.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK66488.1 - 4.9e-05 23.4 0.0 0.00014 21.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 GAK66488.1 - 0.0088 16.1 1.1 0.015 15.3 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle ERCC3_RAD25_C PF16203.5 GAK66488.1 - 0.021 14.0 0.1 0.046 12.9 0.1 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-CCHC_4 PF14392.6 GAK66488.1 - 0.045 13.5 0.3 0.096 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 GAK66488.1 - 0.082 12.8 2.5 0.19 11.5 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Phage_endo_I PF05367.11 GAK66488.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Phage endonuclease I RINGv PF12906.7 GAK66489.1 - 1.7e-14 53.6 10.2 3.2e-14 52.8 10.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GAK66489.1 - 0.47 10.8 11.8 0.87 10.0 11.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 GAK66489.1 - 4.5 7.4 6.8 11 6.1 6.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad9 PF04139.13 GAK66490.1 - 1.1e-51 175.7 0.0 1.4e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Rad9 Trp_syntA PF00290.20 GAK66491.1 - 6.1e-89 297.3 0.3 1e-88 296.6 0.3 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 GAK66491.1 - 1.5e-47 162.4 0.2 3.1e-47 161.4 0.2 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 GAK66491.1 - 0.02 14.3 0.3 0.075 12.5 0.1 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein PA PF02225.22 GAK66491.1 - 0.16 12.0 0.9 0.89 9.6 0.2 2.6 2 1 0 2 2 2 0 PA domain Pkinase PF00069.25 GAK66492.1 - 5.2e-73 245.7 0.0 6.7e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66492.1 - 3.6e-47 160.8 0.0 5e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAK66492.1 - 2.1e-23 82.4 0.0 4.9e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAK66492.1 - 1.5e-06 27.3 0.0 2.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAK66492.1 - 3.1e-05 23.5 0.0 7e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAK66492.1 - 0.011 15.1 0.4 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK66492.1 - 0.021 14.8 0.2 0.28 11.1 0.3 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 GAK66492.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain RhoGAP PF00620.27 GAK66493.1 - 9.3e-46 155.4 0.0 1.7e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 GAK66493.1 - 1.8e-14 53.8 0.4 8.9e-14 51.5 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HLH PF00010.26 GAK66494.1 - 4.3e-08 33.0 0.7 1.1e-07 31.7 0.1 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3135 PF11333.8 GAK66494.1 - 0.045 14.0 0.5 0.1 12.8 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) LPP20 PF02169.16 GAK66495.1 - 0.21 11.9 0.2 0.34 11.3 0.2 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein DUF202 PF02656.15 GAK66496.1 - 3.1e-11 43.5 0.3 3.1e-11 43.5 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Jiraiya PF15038.6 GAK66496.1 - 0.031 13.7 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Jiraiya SPX PF03105.19 GAK66496.1 - 0.82 9.5 4.2 1.3 8.8 4.2 1.3 1 0 0 1 1 1 0 SPX domain PITH PF06201.13 GAK66497.1 - 1.4e-31 109.8 0.0 2.5e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 GAK66497.1 - 1.3e-19 70.1 0.1 4.1e-19 68.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAK66497.1 - 0.00014 22.2 0.2 0.011 16.2 0.2 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAK66497.1 - 0.016 15.5 0.2 5.7 7.4 0.1 2.6 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 GAK66497.1 - 0.031 14.2 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 GAK66497.1 - 0.046 13.9 0.4 0.26 11.5 0.4 2.3 1 1 0 1 1 1 0 Thioredoxin-like DUF4366 PF14283.6 GAK66497.1 - 0.17 11.9 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MPS2 PF17060.5 GAK66497.1 - 0.49 9.6 4.1 0.95 8.7 4.1 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 TSC22 PF01166.18 GAK66497.1 - 2.9 8.3 7.6 17 5.8 0.5 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family Peptidase_C97 PF05903.14 GAK66498.1 - 6.8e-37 126.6 0.0 1.2e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 GAK66498.1 - 9e-32 110.4 3.9 1.7e-31 109.5 3.9 1.4 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 GAK66498.1 - 5.3e-09 36.0 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAK66498.1 - 5.3e-05 22.7 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAK66498.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain SSF PF00474.17 GAK66499.1 - 4.2e-22 78.6 32.3 6.2e-22 78.0 32.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SdpI PF13630.6 GAK66499.1 - 0.064 13.4 0.5 0.064 13.4 0.5 6.7 7 3 0 7 7 7 0 SdpI/YhfL protein family An_peroxidase PF03098.15 GAK66500.1 - 1.7e-42 145.7 0.0 1.2e-25 90.1 0.0 3.5 1 1 2 3 3 3 3 Animal haem peroxidase T2SSM_b PF10741.9 GAK66500.1 - 0.019 14.8 2.8 0.037 13.8 2.8 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b p450 PF00067.22 GAK66500.1 - 0.18 10.5 0.1 0.38 9.4 0.0 1.5 2 0 0 2 2 2 0 Cytochrome P450 zf-HIT PF04438.16 GAK66501.1 - 2.8e-09 36.7 10.0 4.5e-09 36.0 10.0 1.3 1 0 0 1 1 1 1 HIT zinc finger Eapp_C PF10238.9 GAK66501.1 - 2.1 8.4 7.3 7.4 6.6 7.3 1.9 1 1 0 1 1 1 0 E2F-associated phosphoprotein zf-B_box PF00643.24 GAK66501.1 - 6.9 6.9 9.4 12 6.2 9.4 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-C6H2 PF15801.5 GAK66501.1 - 9.7 6.6 10.3 18 5.7 10.3 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gar1 PF04410.14 GAK66502.1 - 1e-36 126.0 0.0 1.2e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region OPT PF03169.15 GAK66503.1 - 8.4e-145 483.8 35.4 9.7e-145 483.6 35.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PrgI PF12666.7 GAK66503.1 - 0.026 15.2 0.1 0.026 15.2 0.1 5.2 4 1 1 5 5 5 0 PrgI family protein DUF1453 PF07301.11 GAK66503.1 - 0.23 11.5 3.1 0.46 10.5 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1453) VIT1 PF01988.19 GAK66503.1 - 2.3 8.0 7.6 0.75 9.6 0.1 3.0 3 0 0 3 3 3 0 VIT family TP2 PF01254.18 GAK66504.1 - 0.042 14.5 4.7 0.03 14.9 3.2 1.5 1 1 1 2 2 2 0 Nuclear transition protein 2 Borrelia_P83 PF05262.11 GAK66504.1 - 3 6.2 17.3 3.5 6.0 17.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DnaJ PF00226.31 GAK66505.1 - 3.9e-22 78.2 0.1 6.9e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain UQ_con PF00179.26 GAK66506.1 - 1.2e-20 73.6 0.0 1.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAK66506.1 - 0.021 15.1 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain SHR3_chaperone PF08229.11 GAK66508.1 - 2.8e-46 156.9 0.0 3.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 SecG PF03840.14 GAK66508.1 - 0.039 14.0 0.1 0.099 12.7 0.1 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit MgtC PF02308.16 GAK66508.1 - 0.053 13.9 1.6 0.3 11.4 0.6 2.1 2 0 0 2 2 2 0 MgtC family Cmyb_C PF09316.10 GAK66508.1 - 0.073 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 C-myb, C-terminal Pribosyltran PF00156.27 GAK66511.1 - 5.9e-16 58.4 0.1 7.5e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAK66511.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RPN7 PF10602.9 GAK66512.1 - 1.8e-52 177.6 1.2 4.3e-52 176.3 1.2 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAK66512.1 - 1.6e-15 57.5 0.1 5.5e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain RRM_1 PF00076.22 GAK66512.1 - 1.3e-13 50.5 0.0 2.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3035 PF11233.8 GAK66512.1 - 0.095 13.0 1.0 0.22 11.8 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) efThoc1 PF11957.8 GAK66513.1 - 6.5e-94 315.3 0.2 8.5e-43 146.7 0.0 3.4 3 0 0 3 3 3 3 THO complex subunit 1 transcription elongation factor KTSC PF13619.6 GAK66514.1 - 0.048 13.5 0.3 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 KTSC domain EAR PF07897.11 GAK66514.1 - 0.19 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression DUF5539 PF17693.1 GAK66515.1 - 0.1 12.3 0.7 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5539) PfkB PF00294.24 GAK66516.1 - 1.6e-35 122.9 0.4 2e-35 122.6 0.4 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aminotran_1_2 PF00155.21 GAK66517.1 - 8.2e-87 291.7 0.0 9.4e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.24 GAK66519.1 - 1.7e-89 300.7 18.9 2.2e-89 300.4 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK66519.1 - 2.3e-17 63.0 45.3 3.3e-16 59.2 19.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAK66519.1 - 0.033 12.5 10.9 0.056 11.7 0.3 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3792 PF12670.7 GAK66519.1 - 5.1 7.3 20.8 3.1 8.0 2.4 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) SMC_Nse1 PF07574.13 GAK66520.1 - 9e-20 71.4 1.9 6.1e-19 68.7 1.9 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 GAK66520.1 - 4.4e-06 26.9 6.3 9.9e-06 25.8 6.3 1.6 1 1 0 1 1 1 1 RING-like domain zf-HC5HC2H_2 PF13832.6 GAK66520.1 - 0.00097 19.3 1.0 0.0025 17.9 1.0 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAK66520.1 - 0.001 19.3 2.2 0.0023 18.1 2.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 GAK66520.1 - 0.41 10.7 4.0 1.2 9.3 4.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ubiquitin PF00240.23 GAK66521.1 - 4.5e-69 228.2 5.4 7.4e-34 115.3 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 GAK66521.1 - 3.6e-32 110.0 6.4 1.7e-15 56.6 0.6 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAK66521.1 - 7.7e-12 45.5 1.3 0.00027 21.3 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain zf-AN1 PF01428.16 GAK66521.1 - 3.6e-10 39.8 5.5 5.9e-10 39.2 5.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger TBK1_ULD PF18396.1 GAK66521.1 - 1.4e-07 31.4 0.3 0.021 14.8 0.1 2.3 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAK66521.1 - 1.5e-07 31.7 0.4 0.024 15.0 0.1 2.3 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAK66521.1 - 2.3e-07 30.9 0.3 0.022 14.9 0.1 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAK66521.1 - 3.2e-06 27.6 0.2 0.065 13.8 0.1 2.3 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 GAK66521.1 - 0.00018 21.4 0.1 0.63 9.8 0.0 2.3 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 GAK66521.1 - 0.0022 17.3 0.3 0.63 9.3 0.0 2.7 2 1 0 3 3 3 1 RNA methyltransferase Ubiquitin_4 PF18036.1 GAK66521.1 - 0.0042 17.1 12.6 10 6.2 0.2 4.5 5 0 0 5 5 5 0 Ubiquitin-like domain DUF3861 PF12977.7 GAK66521.1 - 0.013 15.6 0.2 8.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 GAK66521.1 - 0.019 14.8 0.4 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 ACT domain DUF2870 PF11069.8 GAK66521.1 - 0.03 14.7 0.0 16 5.9 0.0 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2870) Big_7 PF17957.1 GAK66521.1 - 0.048 14.4 0.0 19 6.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig domain TmoB PF06234.12 GAK66521.1 - 0.085 13.0 0.9 20 5.4 0.1 2.8 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) FlgD_ig PF13860.6 GAK66521.1 - 0.32 10.9 1.3 28 4.6 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain Tash_PEST PF07708.11 GAK66521.1 - 0.47 10.7 9.6 4.4 7.6 1.5 2.3 2 0 0 2 2 2 0 Tash protein PEST motif Plexin_cytopl PF08337.12 GAK66521.1 - 1.5 7.4 5.1 14 4.2 0.3 3.0 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Myosin_head PF00063.21 GAK66522.1 - 3.8e-263 874.8 0.0 5.6e-263 874.2 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 GAK66522.1 - 2.3e-27 95.3 0.9 2.3e-27 95.3 0.9 2.7 3 0 0 3 3 2 1 DIL domain IQ PF00612.27 GAK66522.1 - 7.5e-17 59.5 31.8 5.3e-05 22.7 0.2 6.8 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.6 GAK66522.1 - 0.0066 16.7 0.0 0.024 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain CALCOCO1 PF07888.11 GAK66522.1 - 0.012 14.5 20.1 0.022 13.6 20.1 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1515 PF07439.11 GAK66522.1 - 0.14 12.2 0.9 0.97 9.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF1192 PF06698.11 GAK66522.1 - 0.43 10.7 12.3 0.19 11.8 5.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Myosin_N PF02736.19 GAK66522.1 - 0.52 10.2 2.2 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain ATG16 PF08614.11 GAK66522.1 - 0.64 10.2 21.7 1.5 9.0 3.8 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_16 PF13191.6 GAK66522.1 - 0.65 10.4 0.0 0.65 10.4 0.0 3.0 3 1 0 3 3 2 0 AAA ATPase domain FAM76 PF16046.5 GAK66522.1 - 2.9 7.1 12.0 6.5 6.0 12.0 1.6 1 0 0 1 1 1 0 FAM76 protein Med9 PF07544.13 GAK66522.1 - 9.3 6.4 9.8 26 5.0 1.4 3.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HEAT_EZ PF13513.6 GAK66523.1 - 1.9e-28 98.5 11.6 2.4e-06 27.9 0.0 10.4 10 0 0 10 10 10 5 HEAT-like repeat HEAT PF02985.22 GAK66523.1 - 6.6e-19 66.4 18.3 0.0073 16.5 0.1 11.7 13 0 0 13 13 11 4 HEAT repeat HEAT_2 PF13646.6 GAK66523.1 - 5.8e-18 65.1 13.3 2.2e-05 24.8 0.2 8.3 5 4 2 8 8 8 4 HEAT repeats UME PF08064.13 GAK66523.1 - 1.2e-12 47.6 2.4 0.024 14.6 0.0 6.7 7 1 1 8 8 6 3 UME (NUC010) domain Cnd1 PF12717.7 GAK66523.1 - 7.7e-12 45.6 2.1 0.0097 16.0 0.0 5.2 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAK66523.1 - 2.5e-08 34.4 0.0 0.058 14.0 0.0 5.2 6 0 0 6 6 4 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 GAK66523.1 - 2.9e-08 33.3 2.0 0.053 12.6 0.0 6.2 4 2 2 7 7 7 1 RNAPII transcription regulator C-terminal IBN_N PF03810.19 GAK66523.1 - 1.5e-07 31.2 0.4 7.3e-07 29.0 0.0 2.5 3 0 0 3 3 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 GAK66523.1 - 1.7e-07 30.2 2.7 0.31 9.6 0.2 4.6 4 1 0 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 GAK66523.1 - 4e-05 23.3 0.0 0.39 10.3 0.0 4.5 4 1 0 4 4 4 1 CLASP N terminal IFRD PF05004.13 GAK66523.1 - 4.3e-05 22.8 0.7 0.16 11.1 0.0 3.7 2 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Xpo1 PF08389.12 GAK66523.1 - 0.00018 21.6 7.9 0.018 15.1 0.5 5.4 5 1 0 5 5 5 1 Exportin 1-like protein MMS19_N PF14500.6 GAK66523.1 - 0.00042 20.0 1.4 0.41 10.2 0.1 4.8 5 0 0 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 GAK66523.1 - 0.0044 16.8 0.0 4.9 6.8 0.0 4.6 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 GAK66523.1 - 0.0056 16.6 6.3 63 3.4 0.0 7.0 8 2 0 8 8 8 0 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.7 GAK66523.1 - 0.01 16.1 0.9 1.5 9.2 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ipi1_N PF12333.8 GAK66523.1 - 0.017 15.7 0.0 32 5.2 0.0 4.6 4 1 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation CAS_CSE1 PF03378.15 GAK66523.1 - 0.018 13.6 0.1 3 6.2 0.0 3.7 5 0 0 5 5 5 0 CAS/CSE protein, C-terminus DUF3437 PF11919.8 GAK66523.1 - 0.022 14.7 2.9 1.2 9.1 0.1 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 GAK66523.1 - 0.058 13.6 0.2 1e+02 3.2 0.0 4.6 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 GAK66523.1 - 0.076 12.1 0.3 13 4.8 0.0 2.7 2 1 0 2 2 2 0 Dopey, N-terminal DUF4423 PF14394.6 GAK66523.1 - 0.19 11.4 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Cnd3 PF12719.7 GAK66523.1 - 0.23 10.6 6.9 3.6 6.7 0.4 4.9 3 3 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 GAK66523.1 - 0.66 10.1 11.0 30 4.9 0.0 7.3 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Bax1-I PF01027.20 GAK66524.1 - 4.8e-35 121.3 8.9 6.9e-35 120.8 8.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Cyclin_N PF00134.23 GAK66525.1 - 4e-08 33.0 0.0 1e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Cyclin, N-terminal domain TFIIB PF00382.19 GAK66525.1 - 0.00013 21.9 0.0 2 8.5 0.1 3.4 2 1 0 2 2 2 2 Transcription factor TFIIB repeat MS_channel PF00924.18 GAK66526.1 - 1.5e-19 70.4 0.4 2.1e-19 69.9 0.4 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 GAK66526.1 - 0.00043 20.0 0.1 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 GAK66526.1 - 0.00046 19.6 0.1 0.00092 18.6 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 GAK66526.1 - 0.0039 16.6 0.2 0.0077 15.7 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GAK66526.1 - 0.0059 16.4 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair RNase_PH PF01138.21 GAK66527.1 - 2.4e-24 86.3 5.1 9.9e-24 84.3 1.1 2.6 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RPN7 PF10602.9 GAK66528.1 - 5.7e-47 159.7 0.0 9.2e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAK66528.1 - 6e-12 46.0 0.0 2.3e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 GAK66528.1 - 0.0069 16.4 0.3 1.7 8.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat CENP-F_N PF10481.9 GAK66528.1 - 0.028 14.1 0.7 0.043 13.5 0.7 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain TPR_7 PF13176.6 GAK66528.1 - 0.031 14.3 0.0 2.4 8.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAK66528.1 - 0.14 11.8 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 TPR repeat AAA PF00004.29 GAK66529.1 - 1.9e-40 138.3 0.0 3.6e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAK66529.1 - 2e-21 75.7 0.1 3.9e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAK66529.1 - 4.9e-10 39.1 0.1 1.2e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAK66529.1 - 0.00023 21.6 0.3 0.052 13.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAK66529.1 - 0.00038 20.5 0.2 0.0043 17.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAK66529.1 - 0.00056 20.1 0.6 0.0054 16.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 GAK66529.1 - 0.0006 19.3 0.2 0.018 14.5 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein RuvB_N PF05496.12 GAK66529.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAK66529.1 - 0.0035 17.6 2.6 0.081 13.2 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAK66529.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAK66529.1 - 0.017 14.5 0.2 0.056 12.8 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 GAK66529.1 - 0.021 14.6 0.1 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.9 GAK66529.1 - 0.033 14.2 1.1 0.078 13.0 1.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF815 PF05673.13 GAK66529.1 - 0.038 13.2 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 GAK66529.1 - 0.054 13.5 0.0 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAK66529.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 GAK66529.1 - 0.14 11.9 0.1 0.35 10.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain UPF0029 PF01205.19 GAK66530.1 - 1.2e-20 73.8 0.0 2.2e-19 69.7 0.0 3.0 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 Adenine_deam_C PF13382.6 GAK66530.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain CLASP_N PF12348.8 GAK66531.1 - 2.8e-76 256.1 2.4 8.3e-65 218.5 0.0 3.4 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 GAK66531.1 - 0.00013 21.9 0.9 5.1 7.6 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Dopey_N PF04118.14 GAK66531.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Dopey, N-terminal IFRD PF05004.13 GAK66531.1 - 0.025 13.7 1.2 0.78 8.8 0.0 3.2 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) DASH_Duo1 PF08651.10 GAK66532.1 - 0.014 15.1 1.3 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Pkinase PF00069.25 GAK66533.1 - 1.7e-51 175.1 0.5 4.1e-51 173.9 0.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66533.1 - 7.1e-22 77.9 0.1 1e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAK66533.1 - 0.016 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 GAK66533.1 - 0.048 13.0 0.2 0.089 12.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAK66533.1 - 0.065 12.8 0.3 0.21 11.1 0.3 1.8 1 1 0 1 1 1 0 RIO1 family TraC_F_IV PF11130.8 GAK66534.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Dscam_C PF12355.8 GAK66534.1 - 1.7 9.6 4.1 1.6 9.7 0.1 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal KASH PF10541.9 GAK66534.1 - 2.1 8.7 11.1 8 6.8 7.1 2.6 2 0 0 2 2 2 0 Nuclear envelope localisation domain UQ_con PF00179.26 GAK66535.1 - 7.8e-47 158.4 0.0 8.8e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAK66535.1 - 0.0016 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAK66535.1 - 0.16 12.2 0.4 0.17 12.2 0.4 1.4 1 1 0 1 1 1 0 RWD domain Rhodanese PF00581.20 GAK66536.1 - 2.7e-16 60.0 0.0 3.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Ccdc124 PF06244.12 GAK66537.1 - 1.9e-26 93.1 13.3 1.9e-26 93.1 13.3 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 NAD_kinase PF01513.21 GAK66538.1 - 2.5e-56 191.0 0.0 3.5e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAK66538.1 - 0.016 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Lipase_GDSL_2 PF13472.6 GAK66538.1 - 0.14 12.5 0.1 5.8 7.3 0.0 2.5 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 GAK66539.1 - 1.6e-28 99.7 24.7 3e-28 98.8 23.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI2 PF06432.11 GAK66541.1 - 3.5e-41 141.5 0.0 4.1e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase MPP6 PF10175.9 GAK66541.1 - 6.7e-06 26.6 0.0 8.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Exo5 PF09810.9 GAK66542.1 - 2.8e-47 162.0 0.0 7.8e-45 153.9 0.0 2.5 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease FAD_binding_4 PF01565.23 GAK66544.1 - 2.1e-21 76.1 0.5 3.3e-21 75.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain PX PF00787.24 GAK66545.1 - 1e-20 73.8 0.0 2.6e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 GAK66545.1 - 0.0008 19.0 6.8 0.0086 15.6 0.7 2.2 2 0 0 2 2 2 2 Vps5 C terminal like PRKCSH PF07915.13 GAK66546.1 - 1.1e-10 42.4 0.4 1.1e-10 42.4 0.4 3.8 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 GAK66546.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Orthopox_F8 PF05886.11 GAK66546.1 - 0.15 12.2 0.2 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Mito_carr PF00153.27 GAK66547.1 - 5.8e-30 103.1 3.8 1.3e-15 57.1 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_pol_B PF00136.21 GAK66548.1 - 2.4e-117 392.5 0.0 3.1e-117 392.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 GAK66548.1 - 1.3e-58 197.8 0.8 2.4e-58 197.0 0.8 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 GAK66548.1 - 3.8e-29 101.9 0.0 5.9e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 GAK66548.1 - 1.1e-17 63.8 8.7 1.1e-17 63.8 8.7 3.1 4 0 0 4 4 4 1 DNA polymerase alpha subunit p180 N terminal VWA_N2 PF16164.5 GAK66548.1 - 0.011 15.9 0.1 0.03 14.5 0.1 1.8 1 0 0 1 1 1 0 VWA N-terminal Sigma70_ner PF04546.13 GAK66548.1 - 1.9 8.3 6.5 37 4.1 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2841 PF11001.8 GAK66550.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) DUF2015 PF09435.10 GAK66551.1 - 4.8e-25 87.6 0.0 7.9e-25 86.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Kinesin PF00225.23 GAK66552.1 - 6.1e-93 311.4 0.0 9.5e-93 310.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAK66552.1 - 6.8e-19 68.3 0.0 1.4e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding PKcGMP_CC PF16808.5 GAK66552.1 - 0.014 15.2 11.0 0.52 10.2 0.7 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase V_ATPase_I PF01496.19 GAK66552.1 - 0.25 9.2 1.1 0.4 8.5 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 GAK66552.1 - 0.38 10.8 5.8 1 9.4 1.4 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MAD PF05557.13 GAK66552.1 - 1.7 6.9 10.7 0.76 8.1 6.8 2.2 2 1 1 3 3 3 0 Mitotic checkpoint protein DUF1664 PF07889.12 GAK66552.1 - 1.8 8.6 4.4 1.2 9.1 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) OmpH PF03938.14 GAK66552.1 - 2.1 8.7 14.0 5.3 7.4 0.2 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BBP1_C PF15272.6 GAK66552.1 - 9.3 6.0 7.4 2.2 8.0 1.8 2.6 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal Ammonium_transp PF00909.21 GAK66553.1 - 9.5e-104 347.2 26.4 9.5e-104 347.2 26.4 1.9 2 0 0 2 2 2 1 Ammonium Transporter Family Cupin_8 PF13621.6 GAK66554.1 - 1.2e-06 28.5 0.2 2.5e-05 24.1 0.2 2.6 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 GAK66554.1 - 1.6e-05 25.3 0.3 0.0012 19.3 0.3 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 GAK66554.1 - 7.3e-05 22.6 12.9 0.00017 21.4 12.9 1.7 1 1 0 1 1 1 1 PHD-finger JHD PF17811.1 GAK66554.1 - 0.0002 21.8 0.0 0.00041 20.8 0.0 1.5 1 0 0 1 1 1 1 Jumonji helical domain PHD_2 PF13831.6 GAK66554.1 - 0.015 14.9 10.4 0.015 14.9 10.4 1.8 2 0 0 2 2 2 0 PHD-finger Rad21_Rec8_N PF04825.13 GAK66555.1 - 0.09 13.0 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein DEAD PF00270.29 GAK66557.1 - 7.5e-48 162.6 0.0 1.4e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK66557.1 - 1.8e-25 89.4 0.1 6.5e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAK66557.1 - 2.2e-19 69.4 0.2 6e-19 68.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAK66557.1 - 8.1e-06 25.9 0.2 3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HECT PF00632.25 GAK66558.1 - 5.7e-72 242.8 0.0 7.7e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TPR_1 PF00515.28 GAK66560.1 - 1.5e-08 34.1 2.1 0.013 15.3 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAK66560.1 - 1.1e-07 31.4 12.6 0.00082 19.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK66560.1 - 8.5e-07 29.0 3.3 0.0011 19.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK66560.1 - 5.4e-06 26.5 1.2 2.8e-05 24.2 1.2 2.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAK66560.1 - 6.5e-06 26.0 1.3 0.17 12.2 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAK66560.1 - 1.3e-05 25.2 0.2 0.4 11.2 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK66560.1 - 0.0057 17.1 0.5 0.0057 17.1 0.5 6.6 6 1 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAK66560.1 - 0.015 15.9 2.8 0.015 15.9 2.8 7.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAK66560.1 - 0.015 14.9 0.4 5.5 6.8 0.0 3.8 3 1 1 4 4 4 0 TPR repeat TPR_7 PF13176.6 GAK66560.1 - 0.018 15.0 3.3 24 5.3 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAK66560.1 - 7.3 6.6 7.7 4.9 7.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SOG2 PF10428.9 GAK66561.1 - 1.2 8.2 26.7 1.4 8.0 26.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 GAK66561.1 - 2.5 7.9 15.3 3.1 7.6 15.3 1.0 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 GAK66561.1 - 3.1 7.3 8.3 3.6 7.1 8.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 GAK66561.1 - 3.5 7.4 3.9 4.1 7.2 3.9 1.2 1 0 0 1 1 1 0 Rifin Nha1_C PF08619.10 GAK66561.1 - 5 6.2 11.0 5.9 6.0 11.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus GREB1 PF15782.5 GAK66561.1 - 8.9 3.3 13.1 10 3.1 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 GAK66562.1 - 6.9 6.6 8.7 2.9 7.9 2.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 GAK66562.1 - 7.2 5.3 16.0 1.2 7.9 7.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Glyco_transf_22 PF03901.17 GAK66563.1 - 5.7e-44 151.0 12.4 6.9e-44 150.7 12.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_L2_C PF03947.18 GAK66564.1 - 2.7e-51 173.0 2.3 9.5e-51 171.3 2.3 2.0 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAK66564.1 - 1.5e-25 88.9 0.5 3e-25 88.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DnaJ PF00226.31 GAK66564.1 - 2.3e-20 72.5 0.0 5.9e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain NuDC PF16273.5 GAK66564.1 - 0.8 10.3 14.1 4.9 7.8 4.6 3.1 2 0 0 2 2 2 0 Nuclear distribution C domain Terminase_4 PF05119.12 GAK66564.1 - 0.88 10.0 4.1 0.96 9.9 0.6 2.9 3 0 0 3 3 3 0 Phage terminase, small subunit LIN37 PF15306.6 GAK66565.1 - 0.4 10.9 7.4 0.67 10.2 2.2 2.8 2 0 0 2 2 2 0 LIN37 DUF3292 PF11696.8 GAK66565.1 - 1.5 7.1 8.3 0.24 9.7 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) GPS2_interact PF15784.5 GAK66565.1 - 1.8 9.0 9.1 3.8 8.0 4.0 2.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF4200 PF13863.6 GAK66565.1 - 5 7.6 13.5 1.4 9.3 10.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Nsp1_C PF05064.13 GAK66566.1 - 6.4e-31 106.6 0.0 1.5e-30 105.4 0.0 1.5 2 0 0 2 2 2 1 Nsp1-like C-terminal region Baculo_PEP_C PF04513.12 GAK66566.1 - 0.1 12.6 3.1 0.33 11.0 1.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 GAK66566.1 - 1.9 9.1 3.2 11 6.5 0.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TRAUB PF08164.12 GAK66567.1 - 4.8e-26 91.1 1.3 8.9e-25 87.0 0.0 3.0 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 GAK66567.1 - 3.2e-24 86.2 0.3 3.2e-24 86.2 0.3 2.4 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TFIIF_alpha PF05793.12 GAK66567.1 - 0.5 8.9 39.6 0.86 8.1 39.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 GAK66567.1 - 0.77 7.8 45.8 0.17 9.9 29.2 2.2 2 0 0 2 2 2 0 DNA polymerase phi Kinesin PF00225.23 GAK66568.1 - 6.6e-96 321.1 0.0 6.6e-96 321.1 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAK66568.1 - 5e-50 169.3 0.0 1.4e-49 167.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF812 PF05667.11 GAK66568.1 - 0.0098 14.8 17.5 0.016 14.1 17.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) KASH_CCD PF14662.6 GAK66568.1 - 0.013 15.4 13.0 0.013 15.4 13.0 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DMPK_coil PF08826.10 GAK66568.1 - 0.039 14.1 0.3 0.039 14.1 0.3 3.8 3 1 1 4 4 4 0 DMPK coiled coil domain like UpxZ PF06603.11 GAK66568.1 - 0.064 13.6 0.0 0.7 10.2 0.0 2.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists AAA_24 PF13479.6 GAK66568.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DASH_Dam1 PF08653.10 GAK66568.1 - 0.14 12.0 0.3 24 4.8 0.0 3.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 Csm1_N PF18504.1 GAK66568.1 - 0.17 12.3 0.2 0.17 12.3 0.2 3.9 1 1 3 4 4 4 0 Csm1 N-terminal domain LPP PF04728.13 GAK66568.1 - 0.33 11.4 8.1 0.17 12.3 0.6 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper AAA_16 PF13191.6 GAK66568.1 - 0.37 11.2 0.0 0.37 11.2 0.0 3.1 2 2 0 2 2 1 0 AAA ATPase domain DUF1664 PF07889.12 GAK66568.1 - 1 9.4 8.3 0.25 11.4 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 GAK66568.1 - 1.6 8.0 14.9 3.3 7.0 14.9 1.4 1 0 0 1 1 1 0 FAM76 protein AAA_13 PF13166.6 GAK66568.1 - 4 5.9 17.1 8.3 4.9 17.1 1.4 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.7 GAK66569.1 - 1.1e-42 145.5 25.2 2e-42 144.7 25.2 1.4 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 GAK66569.1 - 2.9e-08 33.4 23.7 6.3e-05 22.5 11.7 2.5 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.6 GAK66569.1 - 0.00087 18.7 22.6 0.0014 18.1 22.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 GAK66569.1 - 0.0091 15.3 22.2 0.026 13.9 7.3 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) CENP-K PF11802.8 GAK66569.1 - 0.014 15.0 2.4 0.014 15.0 2.4 2.2 1 1 1 2 2 2 0 Centromere-associated protein K DUF1664 PF07889.12 GAK66569.1 - 0.025 14.6 2.6 0.025 14.6 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 GAK66569.1 - 0.039 13.4 15.0 0.069 12.6 15.0 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Borrelia_P83 PF05262.11 GAK66569.1 - 0.044 12.3 11.2 0.061 11.8 11.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Csm1_N PF18504.1 GAK66569.1 - 0.11 12.8 22.4 0.058 13.7 5.5 3.6 1 1 2 3 3 3 0 Csm1 N-terminal domain HrpB7 PF09486.10 GAK66569.1 - 0.11 12.8 16.9 0.51 10.7 6.6 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) FPP PF05911.11 GAK66569.1 - 0.14 10.3 18.7 0.17 10.0 18.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil PI3K_P85_iSH2 PF16454.5 GAK66569.1 - 0.15 11.6 16.9 2 8.0 7.4 2.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 GAK66569.1 - 0.18 11.2 12.4 0.29 10.4 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GAK66569.1 - 0.22 11.0 7.7 0.29 10.6 7.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4763 PF15960.5 GAK66569.1 - 0.26 10.6 12.5 0.62 9.3 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) FlaC_arch PF05377.11 GAK66569.1 - 0.3 11.5 11.4 8 6.9 2.1 4.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CtIP_N PF10482.9 GAK66569.1 - 0.33 11.0 15.3 0.27 11.3 12.4 2.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain SlyX PF04102.12 GAK66569.1 - 0.6 10.8 11.2 3.9 8.2 1.6 3.3 2 2 1 3 3 2 0 SlyX KASH_CCD PF14662.6 GAK66569.1 - 0.61 9.9 21.8 26 4.5 21.8 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 GAK66569.1 - 0.71 10.1 26.0 0.64 10.2 15.5 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 GAK66569.1 - 0.76 10.0 28.7 1.5 9.0 25.6 2.4 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 GAK66569.1 - 0.82 9.3 24.7 4.3 6.9 1.7 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 GAK66569.1 - 0.92 9.7 10.5 3 8.0 1.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 GAK66569.1 - 0.96 9.9 20.9 1.4 9.3 20.7 1.5 1 1 0 1 1 1 0 Fez1 DUF3584 PF12128.8 GAK66569.1 - 0.96 6.9 19.8 0.6 7.6 6.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.8 GAK66569.1 - 1 9.7 12.4 0.29 11.5 8.2 2.1 1 1 1 2 2 2 0 YlqD protein KLRAQ PF10205.9 GAK66569.1 - 1.1 9.5 14.5 0.64 10.3 2.3 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF812 PF05667.11 GAK66569.1 - 1.1 8.0 21.0 2 7.2 9.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DHR10 PF18595.1 GAK66569.1 - 1.2 9.2 27.6 0.33 11.0 12.4 3.2 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain TRAF_BIRC3_bd PF16673.5 GAK66569.1 - 1.2 8.9 10.8 0.17 11.7 0.5 3.2 3 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF4559 PF15112.6 GAK66569.1 - 1.3 8.6 13.6 1.9 8.1 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Spc7 PF08317.11 GAK66569.1 - 1.8 7.3 23.0 3.3 6.5 12.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GAK66569.1 - 2 8.5 24.5 15 5.6 24.5 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 GAK66569.1 - 2.3 6.3 20.7 3.2 5.8 20.7 1.1 1 0 0 1 1 1 0 HOOK protein DUF4201 PF13870.6 GAK66569.1 - 2.4 7.9 17.4 1.8 8.3 7.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 GAK66569.1 - 2.5 8.6 7.8 3.5 8.2 1.3 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 GAK66569.1 - 2.6 8.1 30.4 0.073 13.1 1.5 3.3 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 GAK66569.1 - 2.7 8.0 23.2 3.4 7.7 9.7 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 GAK66569.1 - 2.8 8.3 13.8 3.2 8.1 5.8 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2968 PF11180.8 GAK66569.1 - 3.1 7.4 15.0 4.5 6.9 7.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) XhlA PF10779.9 GAK66569.1 - 3.5 7.9 18.6 9.8 6.5 2.4 3.5 1 1 1 3 3 3 0 Haemolysin XhlA DUF641 PF04859.12 GAK66569.1 - 3.6 7.9 15.8 0.43 10.9 2.4 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) YabA PF06156.13 GAK66569.1 - 3.8 8.2 11.9 23 5.7 5.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA PspA_IM30 PF04012.12 GAK66569.1 - 4.3 6.9 21.5 12 5.4 6.3 2.8 1 1 1 2 2 2 0 PspA/IM30 family Spectrin PF00435.21 GAK66569.1 - 4.3 7.9 17.1 0.9 10.1 6.8 3.1 1 1 1 2 2 2 0 Spectrin repeat DUF724 PF05266.14 GAK66569.1 - 4.7 7.0 17.3 4 7.2 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) T3SSipB PF16535.5 GAK66569.1 - 4.7 7.7 13.4 2.7 8.5 1.3 1.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB TMF_DNA_bd PF12329.8 GAK66569.1 - 4.9 7.2 26.0 2.4 8.2 9.6 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 GAK66569.1 - 5.1 7.5 20.5 1.6 9.1 10.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HIP1_clath_bdg PF16515.5 GAK66569.1 - 5.3 7.7 21.0 5 7.8 7.7 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 GAK66569.1 - 5.6 5.4 8.2 8.6 4.8 8.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Macoilin PF09726.9 GAK66569.1 - 5.7 5.4 16.4 7.9 4.9 16.4 1.2 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 GAK66569.1 - 6.8 4.5 9.2 11 3.8 9.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 GAK66569.1 - 6.9 7.0 18.0 14 6.0 15.9 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ERM PF00769.19 GAK66569.1 - 7.1 6.4 24.8 18 5.1 24.0 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fzo_mitofusin PF04799.13 GAK66569.1 - 7.8 6.0 12.3 0.87 9.1 4.9 2.2 1 1 1 2 2 2 0 fzo-like conserved region bZIP_1 PF00170.21 GAK66569.1 - 8.6 6.5 15.2 3.5 7.8 2.8 3.4 2 1 1 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 GAK66569.1 - 8.7 6.5 16.6 3.2 7.9 4.0 3.5 2 1 1 3 3 3 0 Basic region leucine zipper GBP_C PF02841.14 GAK66569.1 - 8.8 5.6 16.6 18 4.6 16.2 1.5 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3552 PF12072.8 GAK66569.1 - 8.8 5.7 21.2 56 3.1 21.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) JIP_LZII PF16471.5 GAK66569.1 - 8.9 6.6 17.7 6.8 6.9 1.1 3.3 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Uds1 PF15456.6 GAK66569.1 - 9.6 6.4 18.6 7.1 6.8 4.7 3.1 1 1 1 2 2 2 0 Up-regulated During Septation Response_reg PF00072.24 GAK66570.1 - 9.1e-16 58.0 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Amidase PF01425.21 GAK66571.1 - 5.4e-106 355.3 2.1 2.7e-105 353.0 2.1 2.0 1 1 0 1 1 1 1 Amidase FMN_dh PF01070.18 GAK66572.1 - 2e-108 362.5 0.0 2.4e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAK66572.1 - 2.2e-05 23.7 0.3 4.1e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAK66572.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 GAK66572.1 - 0.0015 17.9 0.1 0.48 9.7 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAK66572.1 - 0.052 13.0 0.0 0.62 9.5 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 GAK66572.1 - 0.13 11.7 0.7 0.19 11.0 0.7 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF4646 PF15496.6 GAK66573.1 - 4.2e-36 124.3 0.3 8.7e-36 123.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) SR-25 PF10500.9 GAK66573.1 - 0.00012 21.8 9.1 0.00012 21.8 9.1 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 GAK66573.1 - 0.0033 18.1 4.7 0.0033 18.1 4.7 2.1 2 0 0 2 2 2 1 Immortalisation up-regulated protein Melibiase_2 PF16499.5 GAK66574.1 - 1.3e-46 159.1 0.0 2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAK66574.1 - 5.6e-11 42.4 0.5 2.9e-10 40.1 0.2 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAK66574.1 - 1.1e-05 24.5 0.0 2.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Melibiase Coq4 PF05019.13 GAK66576.1 - 8.5e-63 211.6 0.0 2.4e-50 170.9 0.0 2.1 1 1 1 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PH_12 PF16457.5 GAK66577.1 - 2.4e-30 105.8 0.0 4.5e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 GAK66577.1 - 9.6e-28 97.5 0.0 1.5e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 GAK66577.1 - 6.4e-20 71.6 0.0 2.5e-19 69.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) PHF5 PF03660.14 GAK66578.1 - 1.6e-49 166.5 6.2 1.8e-49 166.2 6.2 1.0 1 0 0 1 1 1 1 PHF5-like protein C1_2 PF03107.16 GAK66578.1 - 0.08 13.3 12.6 0.59 10.5 2.7 2.4 1 1 1 2 2 2 0 C1 domain PolC_DP2 PF03833.13 GAK66578.1 - 0.1 10.4 3.5 0.11 10.3 3.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 GAK66578.1 - 0.18 11.8 9.6 1.5 8.9 1.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.15 GAK66578.1 - 0.74 9.4 13.0 0.66 9.6 0.8 3.3 3 0 0 3 3 3 0 RecR protein DUF2039 PF10217.9 GAK66578.1 - 0.92 9.9 8.7 0.77 10.1 1.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-C3HC4_3 PF13920.6 GAK66578.1 - 1.6 8.7 13.0 2.9 7.8 4.9 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C6H2 PF15801.5 GAK66578.1 - 2.2 8.7 7.9 2 8.8 2.0 2.7 2 1 1 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding TF_Zn_Ribbon PF08271.12 GAK66578.1 - 3.8 7.1 12.2 1.2 8.7 1.4 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding Prok-RING_1 PF14446.6 GAK66578.1 - 8.3 6.4 12.4 1.6 8.7 2.1 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Fungal_trans PF04082.18 GAK66579.1 - 3.6e-13 49.2 0.0 5.4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK66579.1 - 0.00035 20.6 11.3 0.00065 19.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.19 GAK66580.1 - 1.4e-22 80.2 6.6 1.9e-22 79.7 6.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AflR PF08493.10 GAK66580.1 - 0.056 12.9 7.0 0.075 12.5 7.0 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Ribosomal_L27 PF01016.19 GAK66581.1 - 4e-31 106.8 0.1 6.9e-31 106.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein KAR9 PF08580.10 GAK66582.1 - 2.6e-14 52.7 21.1 2.6e-14 52.7 21.1 4.8 2 1 1 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.17 GAK66582.1 - 0.00093 19.2 0.2 0.0021 18.1 0.2 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.21 GAK66582.1 - 0.14 12.6 4.4 6.2 7.4 0.1 3.8 4 0 0 4 4 4 0 Spectrin repeat ATG16 PF08614.11 GAK66582.1 - 0.59 10.3 6.2 18 5.5 0.3 3.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_transf_21 PF13506.6 GAK66583.1 - 1.5e-21 76.6 0.3 1.7e-08 34.1 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 GAK66583.1 - 1.6e-09 38.0 0.2 2.1e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DUF1548 PF07579.11 GAK66583.1 - 0.2 12.0 0.0 3.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) Lyase_1 PF00206.20 GAK66584.1 - 8.4e-96 321.0 0.0 1.3e-95 320.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 GAK66584.1 - 1.1e-24 86.9 0.0 2.6e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal CbiG_N PF11760.8 GAK66585.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Methyltransf_31 PF13847.6 GAK66587.1 - 4.8e-25 88.1 0.0 1.2e-24 86.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK66587.1 - 7.7e-23 81.0 0.0 1.9e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK66587.1 - 8.4e-23 80.9 0.0 6.3e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DUF1772 PF08592.11 GAK66587.1 - 4.2e-22 78.9 12.4 4.2e-22 78.9 12.4 3.0 2 2 0 2 2 2 1 Domain of unknown function (DUF1772) Methyltransf_12 PF08242.12 GAK66587.1 - 4.5e-16 59.4 0.0 1.2e-15 58.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK66587.1 - 3.5e-14 53.0 0.0 6.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK66587.1 - 7.2e-14 51.7 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAK66587.1 - 1.9e-07 30.8 0.0 4.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAK66587.1 - 7.2e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAK66587.1 - 0.00018 21.6 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAK66587.1 - 0.00019 21.1 0.0 0.0082 15.8 0.0 2.2 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 GAK66587.1 - 0.00025 20.6 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.12 GAK66587.1 - 0.00055 19.1 0.0 0.0017 17.5 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.11 GAK66587.1 - 0.0009 18.2 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 GAK66587.1 - 0.0028 17.5 0.1 0.02 14.7 0.0 2.0 1 1 0 2 2 2 1 Hypothetical methyltransferase CheR PF01739.18 GAK66587.1 - 0.0052 16.3 0.0 0.45 10.0 0.0 2.3 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 GAK66587.1 - 0.0084 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 GAK66587.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Pox_MCEL PF03291.16 GAK66587.1 - 0.021 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme NodS PF05401.11 GAK66587.1 - 0.03 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 GAK66587.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 GAK66587.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.20 GAK66587.1 - 0.092 11.8 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 GAK66587.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RVT_2 PF07727.14 GAK66588.1 - 8.4e-37 127.1 0.0 1.7e-36 126.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAK66588.1 - 2.3e-21 76.2 0.1 5.4e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 GAK66588.1 - 4.9e-10 39.2 0.4 4.9e-10 39.2 0.4 2.2 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 GAK66588.1 - 5.8e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotrans_gag PF03732.17 GAK66588.1 - 2e-06 28.0 0.3 6e-06 26.5 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 GAK66588.1 - 8.8e-06 25.6 3.7 8.8e-06 25.6 3.7 1.8 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.6 GAK66588.1 - 0.00076 19.2 0.4 0.0036 17.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Alpha-E PF04168.12 GAK66588.1 - 0.0047 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. Occludin_ELL PF07303.13 GAK66588.1 - 0.14 12.9 4.3 6.2 7.6 0.2 2.9 2 0 0 2 2 2 0 Occludin homology domain DUF3405 PF11885.8 GAK66590.1 - 6.2e-53 180.2 0.6 2.4e-33 115.5 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) ECH_1 PF00378.20 GAK66591.1 - 2.6e-38 131.8 0.0 1.8e-34 119.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK66591.1 - 4.2e-12 46.2 0.0 5.4e-11 42.6 0.0 2.1 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase HBD PF18534.1 GAK66591.1 - 0.022 14.9 0.0 0.084 13.0 0.0 1.9 1 0 0 1 1 1 0 Helical bundle domain Sugar_tr PF00083.24 GAK66594.1 - 2.8e-75 253.9 14.7 4.1e-75 253.4 14.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK66594.1 - 9.5e-19 67.5 28.8 1e-11 44.4 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 GAK66595.1 - 1e-59 198.5 12.8 1.8e-22 79.0 0.3 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4574 PF15141.6 GAK66595.1 - 0.039 13.8 0.3 2.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Tim17 PF02466.19 GAK66595.1 - 1.5 9.2 19.6 1.5 9.2 8.0 3.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family PrpF PF04303.13 GAK66596.1 - 7.2e-86 288.5 0.1 1.3e-85 287.6 0.1 1.3 1 1 0 1 1 1 1 PrpF protein Fungal_trans PF04082.18 GAK66597.1 - 7e-23 81.0 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK66597.1 - 5.5e-07 29.6 17.1 8.6e-07 29.0 17.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 GAK66599.1 - 4.4e-50 170.8 54.0 6e-50 170.3 54.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAK66599.1 - 3.8e-25 88.4 50.5 5.2e-25 88.0 50.5 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.26 GAK66601.1 - 1.4e-21 76.8 0.4 2.2e-21 76.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK66601.1 - 2.2e-19 69.3 2.4 5.6e-19 68.0 1.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 GAK66601.1 - 1.1e-05 25.0 0.1 1.7e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAK66601.1 - 0.011 16.8 0.0 0.019 16.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Hydrolase_4 PF12146.8 GAK66604.1 - 1.4e-16 60.5 0.0 1.1e-09 37.9 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAK66604.1 - 4.1e-15 56.1 0.2 1.8e-10 40.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK66604.1 - 4.2e-06 27.5 0.1 5.5e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 GAK66604.1 - 1.5e-05 23.9 0.0 0.021 13.5 0.0 2.4 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 GAK66604.1 - 0.0014 18.2 0.0 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 GAK66604.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 GAK66604.1 - 0.0036 16.9 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 GAK66604.1 - 0.022 14.7 0.0 0.31 10.9 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAK66604.1 - 0.028 13.9 0.0 0.32 10.4 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 GAK66604.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Peptidase_M76 PF09768.9 GAK66605.1 - 1.1e-67 227.0 0.1 1.3e-67 226.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 GAK66605.1 - 0.0075 16.1 1.5 0.013 15.3 1.3 1.5 1 1 0 1 1 1 1 SprT-like family Rcd1 PF04078.13 GAK66606.1 - 1.7e-123 411.0 2.4 2.1e-123 410.7 2.4 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cyto_heme_lyase PF01265.17 GAK66607.1 - 2.7e-34 119.1 16.1 8.1e-30 104.4 16.2 4.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase PMM PF03332.13 GAK66608.1 - 1.9e-100 335.2 0.7 4.7e-100 333.9 0.7 1.6 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GAK66608.1 - 8.7e-05 22.4 0.0 0.0014 18.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mre11_DNA_bind PF04152.14 GAK66609.1 - 1.7e-46 158.7 0.0 1.7e-46 158.7 0.0 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GAK66609.1 - 4.6e-13 50.1 0.1 1.4e-12 48.5 0.1 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAK66609.1 - 2.3e-05 24.6 0.8 0.001 19.3 0.8 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Siah-Interact_N PF09032.11 GAK66609.1 - 9.2 6.7 7.0 0.62 10.4 0.6 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal NAT PF04768.13 GAK66610.1 - 5.7e-32 110.7 0.2 3.9e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Barstar PF01337.18 GAK66610.1 - 0.069 13.2 0.0 0.41 10.7 0.0 2.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Asparaginase_2 PF01112.18 GAK66612.1 - 1.5e-62 211.4 0.7 6.3e-50 169.9 0.2 2.2 2 0 0 2 2 2 2 Asparaginase Pec_lyase_C PF00544.19 GAK66613.1 - 6.6e-15 55.3 1.7 1e-13 51.4 1.7 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GAK66613.1 - 0.00015 21.7 2.1 0.0011 18.9 2.2 2.1 1 1 0 1 1 1 1 Right handed beta helix region Collagen PF01391.18 GAK66613.1 - 0.042 13.6 44.9 0.56 10.0 32.3 2.6 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) RR_TM4-6 PF06459.12 GAK66613.1 - 0.25 11.2 19.6 0.37 10.6 19.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop53 PF07767.11 GAK66613.1 - 2 7.7 30.9 2.9 7.2 30.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SAPS PF04499.15 GAK66613.1 - 9.3 4.9 13.2 13 4.4 13.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UBX PF00789.20 GAK66616.1 - 2.6e-07 30.7 0.0 4.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain ArAE_2 PF10334.9 GAK66617.1 - 1.8e-59 201.3 0.0 3.8e-59 200.3 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 GAK66617.1 - 2e-43 149.1 7.6 8.9e-38 130.5 0.9 3.3 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAK66617.1 - 2.8e-10 40.4 13.7 2.8e-10 40.4 13.7 3.3 3 0 0 3 3 3 1 Fusaric acid resistance protein-like Glyoxalase_6 PF18029.1 GAK66617.1 - 0.072 13.9 1.3 0.43 11.4 1.3 2.3 1 0 0 1 1 1 0 Glyoxalase-like domain ALMT PF11744.8 GAK66617.1 - 0.097 11.5 3.2 0.24 10.2 3.2 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter CMAS PF02353.20 GAK66618.1 - 1.3e-34 119.8 3.2 2e-34 119.1 3.2 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 GAK66618.1 - 2.4e-13 50.6 0.0 6.7e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK66618.1 - 4.7e-12 46.4 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK66618.1 - 2.9e-10 40.1 0.0 1e-09 38.4 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK66618.1 - 5.7e-10 39.3 0.1 1.2e-09 38.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK66618.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAK66618.1 - 2.5e-07 31.4 0.0 5.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAK66618.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 GAK66618.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 GAK66618.1 - 0.0011 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 GAK66618.1 - 0.0056 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 GAK66618.1 - 0.012 15.2 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW GidB PF02527.15 GAK66618.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.18 GAK66618.1 - 0.02 14.2 0.0 0.072 12.4 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GAK66618.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 GAK66618.1 - 0.044 13.9 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_17 PF12692.7 GAK66618.1 - 0.056 13.5 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DUF938 PF06080.12 GAK66618.1 - 0.094 12.5 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) PTS_2-RNA PF01885.16 GAK66619.1 - 4.1e-65 219.2 0.0 6.4e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family tRNA_int_end_N2 PF12928.7 GAK66619.1 - 8.1e-21 74.0 0.0 1.9e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 GAK66619.1 - 0.013 15.2 0.4 0.06 13.0 0.0 2.1 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain DUF4228 PF14009.6 GAK66619.1 - 0.13 12.7 8.3 0.89 9.9 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) SET PF00856.28 GAK66620.1 - 7e-06 26.5 0.1 1.2e-05 25.7 0.1 1.5 1 1 0 1 1 1 1 SET domain V-ATPase_C PF03223.15 GAK66621.1 - 5e-128 427.6 0.9 5.6e-128 427.5 0.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF4110 PF13422.6 GAK66621.1 - 0.0058 16.7 1.0 0.018 15.1 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) DUF4404 PF14357.6 GAK66621.1 - 4 8.2 6.7 28 5.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RRM_1 PF00076.22 GAK66622.1 - 1.2e-15 57.0 0.0 3.6e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK66622.1 - 8.8e-10 38.6 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif adh_short PF00106.25 GAK66623.1 - 5.5e-35 120.6 0.8 8.6e-35 120.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK66623.1 - 1.6e-24 86.7 1.6 2.2e-24 86.3 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK66623.1 - 2.5e-11 43.8 1.3 3.6e-11 43.3 1.3 1.2 1 0 0 1 1 1 1 KR domain LigB PF02900.18 GAK66623.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Cupin_1 PF00190.22 GAK66624.1 - 5.1e-38 130.1 0.0 1.9e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GAK66624.1 - 9.7e-25 86.1 0.5 2.3e-13 49.6 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 GAK66624.1 - 1.1e-11 44.7 0.3 2.3e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 GAK66624.1 - 1.1e-05 25.0 0.0 0.026 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 GAK66624.1 - 0.00024 21.0 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Ectoine_synth PF06339.12 GAK66624.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Ectoine synthase 3-HAO PF06052.12 GAK66624.1 - 0.054 13.1 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 GAK66624.1 - 0.064 13.4 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family Cupin_7 PF12973.7 GAK66624.1 - 0.12 12.3 0.0 8.3 6.4 0.0 2.6 2 0 0 2 2 2 0 ChrR Cupin-like domain GST_N_3 PF13417.6 GAK66625.1 - 9.7e-14 51.5 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAK66625.1 - 1.4e-10 41.4 0.1 2.3e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK66625.1 - 4e-10 39.9 0.0 7.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAK66625.1 - 0.00047 20.3 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAK66625.1 - 0.02 14.9 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fasciclin PF02469.22 GAK66626.1 - 2.1e-33 115.3 3.4 3.5e-23 82.2 0.5 2.3 2 0 0 2 2 2 2 Fasciclin domain Serglycin PF04360.12 GAK66626.1 - 0.0046 16.9 3.7 0.012 15.6 3.7 1.7 1 0 0 1 1 1 1 Serglycin Rhomboid PF01694.22 GAK66628.1 - 5.2e-13 49.3 14.2 5.2e-13 49.3 14.2 2.1 2 1 0 2 2 2 1 Rhomboid family GHMP_kinases_N PF00288.26 GAK66628.1 - 0.19 12.0 1.7 0.61 10.4 1.7 2.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain RNA_pol_Rpb4 PF03874.16 GAK66629.1 - 8e-11 42.3 1.0 2.7e-10 40.6 1.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.32 GAK66630.1 - 1.5e-48 161.7 15.2 1.1e-11 45.1 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66630.1 - 2.2e-18 66.4 1.8 8.4e-06 26.0 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK66630.1 - 2.3e-09 36.5 15.5 0.019 13.7 0.1 5.7 1 1 5 6 6 6 6 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAK66630.1 - 3e-09 36.3 6.1 0.34 9.8 0.1 4.9 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAK66630.1 - 9.7e-09 35.4 2.1 1.3e-06 28.5 0.1 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAK66630.1 - 3.5e-05 23.3 0.0 0.068 12.5 0.0 3.0 1 1 1 3 3 3 2 WD40-like domain Coatomer_WDAD PF04053.14 GAK66630.1 - 5.9e-05 22.3 0.1 0.17 10.9 0.1 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Frtz PF11768.8 GAK66630.1 - 0.0029 16.0 0.4 0.061 11.6 0.0 2.4 1 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 GAK66630.1 - 0.017 14.8 3.6 0.11 12.1 0.1 3.3 4 0 0 4 4 4 0 TUP1-like enhancer of split DUF1295 PF06966.12 GAK66631.1 - 6.4e-37 127.3 3.5 1.1e-35 123.3 3.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Kinesin PF00225.23 GAK66632.1 - 1.2e-108 363.0 0.5 3.9e-108 361.3 0.5 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAK66632.1 - 1.6e-24 86.5 0.0 6.9e-24 84.5 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding TSC22 PF01166.18 GAK66632.1 - 0.075 13.4 1.0 0.45 10.9 0.4 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family EutN_CcmL PF03319.13 GAK66632.1 - 0.12 12.9 0.5 0.47 11.1 0.5 2.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome Bacillus_HBL PF05791.11 GAK66632.1 - 0.98 9.2 10.0 0.087 12.6 0.4 3.4 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 GAK66632.1 - 3.3 7.8 34.6 0.39 10.8 0.2 7.4 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 GAK66632.1 - 7 6.9 6.2 17 5.7 0.0 4.1 2 1 0 2 2 2 0 AAA domain SAICAR_synt PF01259.18 GAK66633.1 - 2.2e-94 315.8 0.0 2.7e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Kinesin PF00225.23 GAK66634.1 - 1.2e-80 271.0 0.0 1.9e-80 270.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAK66634.1 - 7.7e-09 35.6 0.0 8.6e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding RIO1 PF01163.22 GAK66635.1 - 5.5e-41 140.2 0.2 1.8e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 GAK66635.1 - 1.6e-33 114.7 0.1 3.5e-33 113.7 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 GAK66635.1 - 2.1e-07 31.1 1.6 9.4e-05 22.4 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 GAK66635.1 - 7.7e-05 22.1 0.0 0.058 12.7 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.12 GAK66635.1 - 0.0028 17.1 18.8 0.0028 17.1 18.8 2.2 2 0 0 2 2 2 1 SDA1 MarR_2 PF12802.7 GAK66635.1 - 0.0094 15.8 0.0 0.074 13.0 0.0 2.3 2 0 0 2 2 2 1 MarR family Prothymosin PF03247.14 GAK66635.1 - 1.2 9.6 34.5 0.49 10.9 16.5 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family RXT2_N PF08595.11 GAK66635.1 - 2.8 7.9 20.2 1.5 8.8 3.2 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 GAK66635.1 - 3.6 6.8 33.6 0.35 10.2 14.8 2.2 2 0 0 2 2 2 0 NOA36 protein BSP_II PF05432.11 GAK66635.1 - 4.7 6.8 30.1 0.13 12.0 15.3 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) E1_DerP2_DerF2 PF02221.15 GAK66636.1 - 8e-26 91.1 0.0 1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAK66636.1 - 0.12 12.8 0.0 0.42 11.0 0.0 2.0 1 1 0 1 1 1 0 ML-like domain DUF4097 PF13349.6 GAK66637.1 - 0.00073 19.0 0.3 0.002 17.5 0.3 1.7 1 1 0 1 1 1 1 Putative adhesin OppC_N PF12911.7 GAK66637.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PPR_2 PF13041.6 GAK66638.1 - 3.8e-44 148.7 0.1 2e-08 34.3 0.0 7.4 6 1 1 7 7 7 6 PPR repeat family PPR_1 PF12854.7 GAK66638.1 - 5.6e-26 89.9 2.0 0.0049 16.5 0.0 9.7 11 0 0 11 11 11 6 PPR repeat PPR_3 PF13812.6 GAK66638.1 - 4.9e-21 74.6 0.2 1.9e-06 27.8 0.0 7.0 5 1 4 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 GAK66638.1 - 4.8e-18 64.1 11.7 0.00032 20.7 0.1 11.1 12 0 0 12 12 12 3 PPR repeat PPR_long PF17177.4 GAK66638.1 - 2.7e-10 40.0 2.8 0.31 10.4 0.0 4.8 3 1 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GAK66638.1 - 0.0023 18.4 3.7 0.21 12.1 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat MNE1 PF13762.6 GAK66638.1 - 0.037 14.0 0.0 9.5 6.2 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial splicing apparatus component Snf7 PF03357.21 GAK66639.1 - 1.7e-33 115.7 10.0 2.1e-33 115.4 10.0 1.1 1 0 0 1 1 1 1 Snf7 TIP39 PF14980.6 GAK66639.1 - 0.099 12.5 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 TIP39 peptide P22_AR_N PF10547.9 GAK66639.1 - 0.21 12.0 3.4 0.75 10.2 0.2 2.2 1 1 0 2 2 2 0 P22_AR N-terminal domain Gluconate_2-dh3 PF13618.6 GAK66639.1 - 2 8.7 5.6 0.82 9.9 2.1 2.0 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Peptidase_M24 PF00557.24 GAK66642.1 - 2.9e-49 167.6 0.0 4.1e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAK66642.1 - 8.2e-41 138.6 0.0 1.5e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GST_N_3 PF13417.6 GAK66643.1 - 1.5e-11 44.5 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK66643.1 - 4.7e-08 32.9 0.0 2.2e-07 30.8 0.0 2.0 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAK66643.1 - 2.5e-06 27.7 0.0 4.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAK66643.1 - 1.8e-05 25.0 0.0 4.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAK66643.1 - 1.9e-05 24.8 0.0 0.00014 22.0 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAK66643.1 - 0.00021 21.4 0.0 0.00051 20.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAK66643.1 - 0.0012 19.3 0.0 0.0033 18.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 GAK66643.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Methyltransf_11 PF08241.12 GAK66644.1 - 5.1e-19 68.7 0.0 2.9e-18 66.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK66644.1 - 3.3e-18 66.2 0.0 1.9e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK66644.1 - 3.4e-17 62.7 0.0 5.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK66644.1 - 3.2e-13 49.8 0.0 4.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK66644.1 - 5.1e-12 46.4 0.0 9.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK66644.1 - 3.7e-10 39.5 0.0 5.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAK66644.1 - 0.0056 16.3 0.0 0.2 11.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.18 GAK66644.1 - 0.039 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_29 PF03141.16 GAK66644.1 - 0.24 9.9 0.0 6 5.3 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 GAK66644.1 - 0.24 10.7 0.1 1 8.7 0.1 1.9 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) IlvN PF07991.12 GAK66645.1 - 3.7e-43 146.9 0.0 6.3e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 GAK66645.1 - 3.9e-41 140.7 0.0 6.2e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 GAK66645.1 - 0.0025 18.4 0.1 0.0069 16.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAK66645.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Band_7 PF01145.25 GAK66646.1 - 1.9e-28 99.6 0.6 3.3e-28 98.9 0.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAK66646.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family DHHA2 PF02833.14 GAK66647.1 - 9.8e-32 110.1 0.3 3.5e-31 108.3 0.1 2.0 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 GAK66647.1 - 1.4e-09 38.1 0.1 3.4e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 DHH family DUF1672 PF07901.11 GAK66647.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Phage_holin_3_7 PF05449.11 GAK66647.1 - 0.47 10.5 4.0 0.45 10.6 1.3 2.2 2 0 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 4HBT_3 PF13622.6 GAK66648.1 - 4.5e-35 122.1 4.3 5.1e-34 118.6 4.3 2.0 1 1 0 1 1 1 1 Thioesterase-like superfamily WD40 PF00400.32 GAK66649.1 - 1e-07 32.5 1.4 0.33 11.9 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat FMN_dh PF01070.18 GAK66650.1 - 4.2e-120 400.9 0.3 4.9e-120 400.7 0.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAK66650.1 - 7.7e-20 70.8 0.0 1.9e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAK66650.1 - 1.5e-05 24.4 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAK66650.1 - 0.00012 21.3 0.1 0.00022 20.4 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GAK66650.1 - 0.0028 17.0 0.0 0.79 9.0 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Arm PF00514.23 GAK66650.1 - 0.0029 17.6 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Vitellogenin_N PF01347.22 GAK66650.1 - 0.046 12.1 0.0 0.064 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region His_biosynth PF00977.21 GAK66650.1 - 0.11 12.0 0.3 0.86 9.0 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein ATPase PF06745.13 GAK66650.1 - 0.14 11.5 0.0 0.41 10.0 0.0 1.6 2 0 0 2 2 2 0 KaiC NMO PF03060.15 GAK66650.1 - 0.16 11.3 1.6 0.15 11.4 0.3 1.5 2 0 0 2 2 2 0 Nitronate monooxygenase Amino_oxidase PF01593.24 GAK66652.1 - 1.5e-12 47.5 0.1 7.4e-11 42.0 0.1 2.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK66652.1 - 4.6e-10 39.6 0.0 1.4e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAK66652.1 - 0.0029 17.6 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAK66652.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK66652.1 - 0.13 11.8 1.1 0.26 10.8 0.1 2.0 2 1 2 4 4 4 0 FAD dependent oxidoreductase RRS1 PF04939.12 GAK66654.1 - 4.8e-56 189.1 2.8 4.8e-56 189.1 2.8 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) WD40 PF00400.32 GAK66655.1 - 1.5e-36 123.7 16.1 4.3e-08 33.7 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66655.1 - 2.8e-11 43.6 0.1 0.005 17.1 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK66655.1 - 0.011 14.4 0.2 0.023 13.3 0.2 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF4592 PF15262.6 GAK66655.1 - 0.62 10.7 5.1 2 9.1 5.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) MIF4G PF02854.19 GAK66656.1 - 1.2e-24 87.1 0.0 9.3e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 GAK66656.1 - 2.6e-15 56.4 0.0 6.5e-15 55.1 0.0 1.7 1 1 0 1 1 1 1 MA3 domain DEAD PF00270.29 GAK66657.1 - 3.5e-39 134.4 0.0 6.7e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK66657.1 - 1.5e-30 105.7 0.0 1.8e-28 99.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK66657.1 - 9.5e-07 29.0 0.0 3.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAK66657.1 - 0.0058 17.0 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DnaJ-X PF14308.6 GAK66657.1 - 0.022 14.2 3.2 0.041 13.3 3.2 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing AAA_22 PF13401.6 GAK66657.1 - 0.15 12.3 0.2 0.79 10.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain CDK5_activator PF03261.15 GAK66657.1 - 6.2 6.3 6.0 25 4.3 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein F-box-like PF12937.7 GAK66658.1 - 1.3e-08 34.6 1.3 2.6e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAK66658.1 - 6.4e-05 22.7 0.2 0.00019 21.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 GAK66658.1 - 0.014 16.2 0.6 0.014 16.2 0.6 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.25 GAK66659.1 - 3.9e-61 206.7 0.2 6.8e-57 192.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66659.1 - 1.9e-40 138.8 0.0 4.2e-37 127.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK66659.1 - 1.7e-07 30.9 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAK66659.1 - 2.3e-05 23.4 0.1 7.9e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAK66659.1 - 0.016 15.1 0.2 0.12 12.3 0.2 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAK66659.1 - 0.023 14.1 0.1 0.044 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 GAK66659.1 - 0.17 10.9 0.1 0.26 10.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MBF1 PF08523.10 GAK66660.1 - 4e-19 68.9 1.7 4.1e-19 68.8 0.1 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 GAK66660.1 - 4.9e-15 55.3 0.3 8.7e-15 54.5 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 GAK66660.1 - 4.3e-06 27.0 0.0 8.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 GAK66660.1 - 0.00028 20.9 0.0 0.00068 19.6 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 GAK66660.1 - 0.051 13.4 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Response_reg PF00072.24 GAK66661.1 - 5.1e-20 71.7 0.0 1.4e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAK66661.1 - 1.7e-15 57.5 0.2 3.5e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAK66661.1 - 1e-06 28.6 0.1 3.1e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 GAK66661.1 - 0.021 15.1 0.1 0.5 10.7 0.0 3.1 3 0 0 3 3 3 0 GAF domain zf-ZPR1 PF03367.13 GAK66662.1 - 6.9e-110 364.0 0.6 7e-55 185.2 0.0 3.0 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 GAK66662.1 - 0.0005 20.1 2.1 0.16 12.0 0.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 GAK66662.1 - 0.0064 15.9 9.9 3 7.4 0.1 3.6 3 0 0 3 3 3 3 zinc-ribbon domain zinc-ribbons_6 PF07191.12 GAK66662.1 - 0.047 13.7 1.9 3.3 7.8 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 GAK66662.1 - 0.052 13.6 7.7 0.1 12.7 0.2 3.1 2 1 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 GAK66662.1 - 0.074 13.0 2.7 6.2 6.8 0.2 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Cytochrome_C7 PF14522.6 GAK66662.1 - 0.37 10.8 3.0 4.6 7.3 0.8 2.6 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Zn-ribbon_8 PF09723.10 GAK66662.1 - 0.93 9.7 8.8 21 5.3 0.4 3.7 3 1 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 GAK66662.1 - 1.7 8.4 9.8 2.3 8.1 0.7 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.6 GAK66662.1 - 6 7.3 7.6 4.2 7.8 0.2 3.3 3 1 0 3 3 3 0 Restriction alleviation protein Lar Pro_isomerase PF00160.21 GAK66663.1 - 9.8e-43 146.1 0.0 2e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 GAK66663.1 - 2.9e-07 30.2 1.1 1.1e-06 28.3 0.0 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 GAK66663.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein SPX PF03105.19 GAK66664.1 - 2.9e-30 106.5 29.4 8.8e-19 68.7 23.5 3.4 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 GAK66664.1 - 4.2e-30 105.2 37.3 5.9e-30 104.7 37.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAK66664.1 - 2.5e-28 99.2 31.0 2.5e-28 99.2 31.0 2.1 1 1 1 2 2 2 2 Citrate transporter ATPase_gene1 PF09527.10 GAK66664.1 - 5.5 7.2 11.4 3.2 8.0 6.1 3.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CAF1C_H4-bd PF12265.8 GAK66665.1 - 8.9e-31 106.0 1.1 2.5e-30 104.5 1.1 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAK66665.1 - 8.4e-26 89.7 7.4 1.5e-05 25.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat NAP PF00956.18 GAK66666.1 - 2.3e-23 82.7 12.7 3.3e-20 72.4 6.8 3.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) HSDR_N_2 PF13588.6 GAK66666.1 - 0.016 15.2 0.3 0.026 14.5 0.3 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) YL1 PF05764.13 GAK66666.1 - 1.8 8.6 7.0 2.4 8.2 7.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 GAK66666.1 - 2.8 8.4 16.3 6.8 7.2 16.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GAK66666.1 - 5.2 6.3 7.8 7.2 5.8 7.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3292 PF11696.8 GAK66667.1 - 3.9e-11 42.1 1.0 6.4e-05 21.5 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) Methyltransf_4 PF02390.17 GAK66668.1 - 3e-49 166.8 0.0 7.2e-37 126.5 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 GAK66668.1 - 0.0074 17.0 0.0 0.095 13.4 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK66668.1 - 0.023 14.5 0.0 0.073 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 GAK66668.1 - 0.026 14.1 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 GAK66668.1 - 0.038 14.7 0.0 0.12 13.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAK66668.1 - 0.043 14.5 0.0 7 7.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Amidase02_C PF12123.8 GAK66668.1 - 0.13 12.0 0.0 0.48 10.2 0.0 2.0 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase NDUFB10 PF10249.9 GAK66669.1 - 0.016 15.7 0.3 0.018 15.5 0.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Prefoldin_2 PF01920.20 GAK66670.1 - 8.4e-20 70.7 4.1 1.2e-19 70.2 4.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 GAK66670.1 - 0.00054 19.9 1.7 0.00075 19.4 1.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 GAK66670.1 - 0.026 14.7 5.2 0.042 14.1 4.3 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 GAK66670.1 - 0.1 13.1 0.9 0.1 13.1 0.9 2.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Helo_like_N PF17111.5 GAK66670.1 - 0.17 11.2 3.2 0.47 9.8 0.9 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins OmpH PF03938.14 GAK66670.1 - 4.8 7.5 9.5 4.4 7.7 2.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CH PF00307.31 GAK66671.1 - 3e-81 268.7 0.0 1e-20 74.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 GAK66671.1 - 2.2e-07 31.2 0.6 6.8e-07 29.6 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 GAK66671.1 - 6.3e-07 29.2 0.0 0.23 11.3 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.32 GAK66671.1 - 0.0002 20.7 0.3 0.095 12.3 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 GAK66671.1 - 0.00092 19.0 0.1 4 7.6 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain CH_2 PF06294.11 GAK66671.1 - 0.011 15.8 0.0 4.1 7.6 0.0 2.9 2 0 0 2 2 2 0 CH-like domain in sperm protein EF-hand_8 PF13833.6 GAK66671.1 - 0.089 12.7 0.0 0.35 10.7 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair Abhydrolase_1 PF00561.20 GAK66672.1 - 1e-11 45.0 0.1 1.2e-10 41.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK66672.1 - 1.5e-11 44.0 0.8 3.6e-11 42.8 0.8 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK66672.1 - 1.7e-07 32.1 0.0 2.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 GAK66672.1 - 0.034 13.8 0.2 0.27 10.9 0.2 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) SMN PF06003.12 GAK66673.1 - 2.2e-06 27.1 0.1 2.2e-06 27.1 0.1 3.6 1 1 3 4 4 4 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 GAK66673.1 - 3.9e-06 26.9 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Tudor_3 PF18115.1 GAK66673.1 - 0.00085 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain PWWP PF00855.17 GAK66673.1 - 0.035 14.5 0.5 0.38 11.2 0.0 2.2 2 0 0 2 2 2 0 PWWP domain Na_H_Exchanger PF00999.21 GAK66674.1 - 8.7e-56 189.3 46.9 1.2e-55 188.8 46.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 GAK66674.1 - 0.064 13.8 0.3 0.43 11.1 0.1 2.3 2 1 0 2 2 2 0 Universal stress protein family Polysacc_deac_2 PF04748.13 GAK66674.1 - 0.067 12.4 0.0 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase CDK2AP PF09806.9 GAK66675.1 - 0.075 13.1 1.6 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Proteasome PF00227.26 GAK66677.1 - 1.4e-49 168.2 0.1 1.9e-49 167.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAK66677.1 - 1.9e-12 46.6 0.3 3.2e-12 45.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature U1snRNP70_N PF12220.8 GAK66678.1 - 1.9e-21 76.5 0.7 1.9e-21 76.5 0.7 2.0 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 GAK66678.1 - 9.7e-18 63.8 0.0 1.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GAK66678.1 - 0.037 14.2 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain RRM_7 PF16367.5 GAK66678.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Homoserine_dh PF00742.19 GAK66678.1 - 0.13 12.1 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 Homoserine dehydrogenase zf-H2C2_2 PF13465.6 GAK66679.1 - 5.3e-14 51.9 8.1 1.4e-06 28.4 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAK66679.1 - 1e-12 47.8 13.8 7.6e-05 23.0 0.0 4.1 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK66679.1 - 1.7e-11 43.9 9.8 0.00056 20.5 0.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAK66679.1 - 8.9e-06 25.9 1.3 0.58 10.5 0.0 3.9 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAK66679.1 - 0.0027 17.6 7.2 0.047 13.7 0.0 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 GAK66679.1 - 0.013 15.8 5.0 1.2 9.6 0.0 4.0 3 1 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 GAK66679.1 - 0.1 12.8 1.8 0.21 11.8 1.8 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-BED PF02892.15 GAK66679.1 - 1.1 9.4 4.7 8.2 6.6 1.4 2.7 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 GAK66679.1 - 8.4 6.3 9.1 0.93 9.3 1.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HATPase_c PF02518.26 GAK66680.1 - 5e-20 72.1 0.2 1.1e-19 71.0 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAK66680.1 - 5.9e-18 65.1 0.0 3.4e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.25 GAK66680.1 - 2.7e-16 59.3 0.0 7.7e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 GAK66680.1 - 0.048 14.0 0.5 0.56 10.6 0.0 3.1 4 1 0 4 4 4 0 GAF domain Spt20 PF12090.8 GAK66682.1 - 0.04 13.5 9.4 0.091 12.4 9.4 1.5 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 GAK66682.1 - 7.4 6.7 16.9 24 5.1 16.9 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Rad60-SLD PF11976.8 GAK66683.1 - 0.03 14.1 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like STAS_2 PF13466.6 GAK66683.1 - 0.096 13.0 0.7 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 STAS domain LSM PF01423.22 GAK66685.1 - 1e-16 60.3 0.2 1.6e-16 59.8 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAK66685.1 - 0.067 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Hfq protein tRNA-synt_1c PF00749.21 GAK66686.1 - 6.6e-110 366.9 0.0 1e-109 366.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAK66686.1 - 4.1e-34 117.9 0.2 8.2e-34 117.0 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 GAK66686.1 - 0.0001 22.4 1.9 0.00047 20.3 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain bMG3 PF11974.8 GAK66686.1 - 0.00035 20.5 0.3 0.11 12.5 0.0 2.9 2 0 0 2 2 2 1 Bacterial alpha-2-macroglobulin MG3 domain GST_C_2 PF13410.6 GAK66686.1 - 0.013 15.5 0.1 0.043 13.8 0.1 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IMUP PF15761.5 GAK66686.1 - 0.024 15.3 9.8 0.065 13.9 9.8 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein GST_C_3 PF14497.6 GAK66686.1 - 0.042 14.1 3.5 0.091 13.0 0.0 3.3 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain ubiquitin PF00240.23 GAK66687.1 - 0.0031 17.2 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAK66687.1 - 0.018 15.6 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAK66687.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like VPS28 PF03997.12 GAK66688.1 - 1.3e-70 237.0 3.4 1.4e-70 236.8 3.4 1.0 1 0 0 1 1 1 1 VPS28 protein DUF4745 PF15923.5 GAK66688.1 - 0.0016 18.4 0.3 0.32 11.0 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4745) Rgp1 PF08737.10 GAK66688.1 - 0.1 11.8 1.1 0.13 11.4 1.1 1.1 1 0 0 1 1 1 0 Rgp1 Hus1 PF04005.12 GAK66689.1 - 3.1e-86 289.1 0.5 3.6e-86 288.9 0.5 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_N PF00705.18 GAK66689.1 - 0.0012 18.5 0.4 0.0027 17.4 0.2 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 GAK66689.1 - 0.0016 18.0 0.1 0.011 15.2 0.1 2.1 1 1 0 1 1 1 1 Rad9 PC_rep PF01851.22 GAK66690.1 - 4.8e-41 137.1 18.0 1.9e-08 34.4 0.0 8.6 8 0 0 8 8 8 6 Proteasome/cyclosome repeat RPN2_C PF18004.1 GAK66690.1 - 4.8e-41 140.3 4.1 6.8e-41 139.9 0.4 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 GAK66690.1 - 6.9e-19 68.0 4.7 2.2e-13 50.4 0.0 5.1 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 GAK66690.1 - 1.6e-05 25.3 5.4 0.028 14.9 0.0 5.4 4 2 2 6 6 6 2 HEAT-like repeat HEAT PF02985.22 GAK66690.1 - 9.2e-05 22.4 0.1 3.5 8.1 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_PBS PF03130.16 GAK66690.1 - 0.019 15.6 1.6 45 5.1 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Katanin_con80 PF13925.6 GAK66690.1 - 0.099 12.7 0.0 29 4.6 0.0 3.1 3 0 0 3 3 3 0 con80 domain of Katanin Beta_elim_lyase PF01212.21 GAK66691.1 - 3.6e-69 233.3 0.0 4.9e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pcc1 PF09341.10 GAK66691.1 - 1.5e-16 60.3 1.4 2.4e-16 59.6 0.2 2.0 2 0 0 2 2 2 1 Transcription factor Pcc1 DegT_DnrJ_EryC1 PF01041.17 GAK66691.1 - 0.0037 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GatB_N PF02934.15 GAK66692.1 - 1e-101 339.9 0.0 1.6e-101 339.3 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GAK66692.1 - 6.2e-26 91.1 0.1 2.6e-25 89.1 0.1 2.0 1 1 0 1 1 1 1 GatB domain zf-LYAR PF08790.11 GAK66693.1 - 5.8e-12 45.3 2.4 1.3e-11 44.2 2.4 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger RRM_1 PF00076.22 GAK66693.1 - 3e-05 23.7 0.0 0.00012 21.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_UBZ PF18439.1 GAK66693.1 - 0.022 14.4 0.4 4.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 GAK66693.1 - 0.035 14.5 2.7 0.49 11.0 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK66693.1 - 0.31 12.0 4.8 3.6 8.7 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Cyclin_N PF00134.23 GAK66697.1 - 2.2e-37 127.6 0.3 3.8e-37 126.9 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAK66697.1 - 2.8e-05 24.2 0.2 2.8e-05 24.2 0.2 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIE-A_C PF11521.8 GAK66697.1 - 4.3 7.7 10.1 3.5 8.0 5.2 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Aconitase PF00330.20 GAK66698.1 - 9e-112 374.4 0.0 8.9e-111 371.1 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAK66698.1 - 6.8e-20 71.7 0.6 1.2e-18 67.8 0.0 2.7 2 1 0 2 2 2 1 Aconitase C-terminal domain Svf1_C PF17187.4 GAK66699.1 - 3.1e-52 176.7 0.0 4.9e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 GAK66699.1 - 2.8e-41 141.3 0.0 4e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain TFIIB PF00382.19 GAK66700.1 - 3.4e-37 126.3 0.5 1e-21 76.8 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GAK66700.1 - 5.2e-13 48.3 1.4 8.3e-13 47.6 1.4 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 GAK66700.1 - 0.0023 18.0 0.0 0.049 13.7 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 GAK66700.1 - 0.0064 16.5 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain PG_binding_1 PF01471.18 GAK66700.1 - 0.078 13.2 0.3 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Cyclin_N PF00134.23 GAK66700.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain YjbE PF11106.8 GAK66700.1 - 0.26 11.5 4.9 0.08 13.2 1.6 1.8 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Nup84_Nup100 PF04121.13 GAK66701.1 - 8.1e-169 563.1 0.0 9.3e-169 562.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 C2 PF00168.30 GAK66702.1 - 4.8e-24 84.6 0.0 3.5e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain PD-C2-AF1 PF09310.10 GAK66703.1 - 0.04 13.3 0.1 0.055 12.9 0.1 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Ribul_P_3_epim PF00834.19 GAK66704.1 - 2e-62 210.1 0.1 2.7e-62 209.7 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 GAK66704.1 - 0.086 12.6 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain F-box-like PF12937.7 GAK66705.1 - 0.0016 18.3 1.2 0.0035 17.2 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK66705.1 - 0.14 12.1 0.3 0.46 10.4 0.3 1.9 1 1 0 1 1 1 0 F-box domain Mago-bind PF09282.10 GAK66706.1 - 2.9e-14 52.6 3.0 2.9e-14 52.6 3.0 2.4 2 0 0 2 2 2 1 Mago binding Dicty_REP PF05086.12 GAK66706.1 - 1 7.3 4.0 1.3 6.9 4.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MAPEG PF01124.18 GAK66707.1 - 1.2e-13 51.1 1.7 1.7e-13 50.6 1.7 1.4 1 0 0 1 1 1 1 MAPEG family GST_N PF02798.20 GAK66708.1 - 1.5e-16 60.5 0.0 3.6e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAK66708.1 - 9.9e-11 41.9 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK66708.1 - 2.1e-08 34.0 0.2 3.7e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAK66708.1 - 1.4e-07 31.6 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAK66708.1 - 4e-07 30.3 0.0 7.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAK66708.1 - 4.6e-07 30.0 0.1 7.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CHZ PF09649.10 GAK66709.1 - 0.11 12.0 7.0 0.49 9.9 4.3 2.8 1 1 1 2 2 2 0 Histone chaperone domain CHZ COX5B PF01215.19 GAK66710.1 - 1.6e-37 128.1 0.0 2.7e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb AMP-binding PF00501.28 GAK66711.1 - 5.3e-75 252.6 0.1 6.9e-44 150.1 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 GAK66711.1 - 1.1e-09 39.1 0.3 4.1e-09 37.3 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 GAK66712.1 - 3.3 7.9 8.6 7.7 6.7 8.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK66713.1 - 8.6e-22 77.4 0.0 1.6e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK66713.1 - 3e-06 27.3 6.0 5.1e-06 26.5 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_4 PF13418.6 GAK66714.1 - 1.7e-22 79.1 6.7 2.2e-06 27.6 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAK66714.1 - 9.6e-10 38.2 5.6 0.00041 20.3 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 GAK66714.1 - 1.7e-08 34.5 18.7 0.0038 17.5 0.4 6.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAK66714.1 - 5.1e-08 32.6 1.3 0.053 13.5 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 GAK66714.1 - 6.6e-08 32.6 6.8 0.029 14.6 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAK66714.1 - 0.00031 20.3 0.1 0.067 12.8 0.0 3.6 4 0 0 4 4 4 1 Kelch motif HET PF06985.11 GAK66714.1 - 0.16 12.3 0.0 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 GAK66715.1 - 6.3e-46 156.8 0.0 8.7e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAK66715.1 - 8.6e-46 156.4 0.0 1.3e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 GAK66715.1 - 5.4e-07 29.4 1.9 1e-06 28.5 1.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 GAK66715.1 - 0.0038 16.6 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAK66715.1 - 0.0055 15.7 0.0 0.0084 15.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAK66715.1 - 0.0085 16.0 0.1 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-HC5HC2H_2 PF13832.6 GAK66715.1 - 0.05 13.8 0.4 0.099 12.8 0.4 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.16 GAK66715.1 - 0.056 13.8 1.1 0.11 12.8 1.1 1.4 1 0 0 1 1 1 0 C1 domain Pkinase_fungal PF17667.1 GAK66715.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PHD PF00628.29 GAK66715.1 - 0.22 11.4 4.1 0.44 10.5 4.1 1.5 1 0 0 1 1 1 0 PHD-finger Ebp2 PF05890.12 GAK66716.1 - 1.7e-87 293.4 17.2 1.7e-87 293.4 17.2 2.3 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 ABC2_membrane PF01061.24 GAK66718.1 - 1.7e-36 125.6 18.4 1.7e-36 125.6 18.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAK66718.1 - 5e-23 82.1 0.0 9.5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAK66718.1 - 0.0012 19.3 0.2 0.0022 18.4 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAK66718.1 - 0.021 14.7 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 GAK66718.1 - 0.033 14.0 0.0 1.5 8.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 GAK66718.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAK66718.1 - 0.23 12.0 0.0 0.36 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 GAK66718.1 - 2.6 7.1 26.6 5.9 5.9 26.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Med15_fungi PF05397.12 GAK66720.1 - 1.4e-28 99.4 2.6 1.4e-28 99.4 2.6 7.2 6 1 1 7 7 7 1 Mediator complex subunit 15 ARID PF01388.21 GAK66720.1 - 1e-18 67.7 0.0 1e-18 67.7 0.0 2.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Glyco_hydro_45 PF02015.16 GAK66723.1 - 3.1e-62 210.2 5.6 4.9e-62 209.6 5.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 PT PF04886.12 GAK66723.1 - 1.8 8.2 36.1 0.097 12.2 14.7 2.9 2 1 1 3 3 3 0 PT repeat C2 PF00168.30 GAK66724.1 - 3.3e-62 207.2 0.0 1.2e-16 60.8 0.0 4.4 4 0 0 4 4 4 4 C2 domain Keratin_2_head PF16208.5 GAK66724.1 - 1.8 8.7 20.1 0.18 11.9 15.1 1.8 2 0 0 2 2 2 0 Keratin type II head Ubiq_cyt_C_chap PF03981.12 GAK66725.1 - 2.4e-27 95.7 0.0 2.8e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone PP2C PF00481.21 GAK66726.1 - 4.2e-37 128.2 0.0 2.2e-33 116.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C WAC_Acf1_DNA_bd PF10537.9 GAK66727.1 - 5.1e-36 123.2 0.1 1.8e-35 121.4 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 GAK66727.1 - 1.2e-25 89.8 0.0 1.2e-25 89.8 0.0 2.6 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 GAK66727.1 - 4.4e-10 39.7 0.5 9.1e-10 38.7 0.5 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 GAK66727.1 - 0.0032 17.0 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 TSA PF03249.13 GAK66727.1 - 5.3 5.7 5.8 9.6 4.9 5.8 1.3 1 0 0 1 1 1 0 Type specific antigen DUF2985 PF11204.8 GAK66728.1 - 5.2e-26 90.6 2.0 9.1e-26 89.8 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Molybdopterin PF00384.22 GAK66729.1 - 1.2e-76 258.4 0.0 5.6e-76 256.2 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 GAK66729.1 - 1.2e-17 64.3 0.1 3.9e-17 62.7 0.1 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 GAK66729.1 - 2.7e-17 62.6 0.1 6.9e-17 61.3 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 GAK66729.1 - 1.2e-16 59.9 0.0 1.2e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 GAK66729.1 - 9.9e-09 35.0 0.5 2.6e-08 33.7 0.5 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 GAK66729.1 - 0.011 15.5 0.2 0.52 10.0 0.1 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Aha1_N PF09229.11 GAK66730.1 - 5.5e-32 110.8 0.0 7.9e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 GAK66730.1 - 2.9e-15 56.6 0.0 2.1e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein bZIP_2 PF07716.15 GAK66731.1 - 0.0054 16.8 6.9 0.011 15.8 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Nefa_Nip30_N PF10187.9 GAK66732.1 - 2.6e-21 76.0 8.9 2.6e-21 76.0 8.9 1.9 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4366 PF14283.6 GAK66732.1 - 0.17 11.9 2.2 0.21 11.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4551 PF15087.6 GAK66732.1 - 3.9 6.2 6.1 4.5 6.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Arm PF00514.23 GAK66733.1 - 5.8e-99 321.5 6.3 3.8e-13 49.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 GAK66733.1 - 1.2e-24 86.5 6.3 2.5e-24 85.5 6.3 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 GAK66733.1 - 1.2e-22 80.0 0.6 9.6e-09 35.6 0.0 6.6 4 3 3 7 7 7 4 HEAT-like repeat Arm_3 PF16186.5 GAK66733.1 - 5.3e-21 73.9 0.3 1.1e-20 73.0 0.3 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 GAK66733.1 - 1.7e-20 73.2 0.1 2.8e-06 27.6 0.0 6.1 1 1 4 6 6 6 6 HEAT repeats HEAT PF02985.22 GAK66733.1 - 4.5e-18 63.8 0.5 6.7e-05 22.8 0.0 7.2 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.20 GAK66733.1 - 6e-07 28.4 0.0 8.3e-05 21.3 0.0 2.7 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.6 GAK66733.1 - 2.9e-05 24.2 0.8 0.036 14.3 0.0 4.0 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_N PF03224.14 GAK66733.1 - 0.00026 20.4 0.0 1.2 8.4 0.0 3.3 1 1 2 3 3 3 3 V-ATPase subunit H Arm_2 PF04826.13 GAK66733.1 - 0.00047 19.7 0.0 0.75 9.2 0.0 3.4 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 GAK66733.1 - 0.00058 20.0 0.0 0.55 10.4 0.0 3.8 4 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.16 GAK66733.1 - 0.0013 19.2 0.4 1.4 9.8 0.1 4.4 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 GAK66733.1 - 0.0057 16.1 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 Mo25-like ABC_trans_aux PF03886.13 GAK66733.1 - 0.016 14.8 0.1 0.083 12.5 0.1 2.2 2 0 0 2 2 2 0 ABC-type transport auxiliary lipoprotein component DCB PF16213.5 GAK66733.1 - 0.053 13.2 0.0 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 GTP_cyclohydro2 PF00925.20 GAK66734.1 - 2e-63 212.9 0.0 5.5e-63 211.4 0.0 1.7 1 1 0 1 1 1 1 GTP cyclohydrolase II Metallophos PF00149.28 GAK66735.1 - 2e-36 126.5 0.1 3.3e-36 125.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAK66735.1 - 1.1e-17 64.2 0.0 2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L7Ae PF01248.26 GAK66737.1 - 2.1e-22 78.7 0.0 2.4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.28 GAK66737.1 - 0.033 14.5 0.1 0.093 13.1 0.0 1.6 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L37e PF01907.19 GAK66738.1 - 3.2e-26 91.3 11.7 3.2e-26 91.3 11.7 1.6 2 1 0 2 2 2 1 Ribosomal protein L37e SelR PF01641.18 GAK66738.1 - 0.0097 16.0 0.3 0.011 15.8 0.3 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 GAK66738.1 - 0.027 14.5 1.5 0.041 13.9 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF2845 PF11006.8 GAK66738.1 - 0.036 14.2 0.3 0.044 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) HypA PF01155.19 GAK66738.1 - 0.086 12.9 0.8 0.11 12.5 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Auto_anti-p27 PF06677.12 GAK66738.1 - 0.21 11.8 1.6 0.33 11.1 1.6 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Leo1 PF04004.13 GAK66739.1 - 1e-50 171.8 0.0 2.7e-50 170.5 0.0 1.8 1 0 0 1 1 1 1 Leo1-like protein Mgm101p PF06420.12 GAK66740.1 - 8.2e-81 269.5 0.0 1.1e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 UBM PF14377.6 GAK66741.1 - 0.011 15.2 0.3 0.23 11.0 0.0 3.1 2 0 0 2 2 2 0 Ubiquitin binding region Acyl-CoA_dh_1 PF00441.24 GAK66742.1 - 1e-43 149.1 2.3 1.8e-43 148.3 2.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAK66742.1 - 2.2e-36 124.9 0.0 4.2e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAK66742.1 - 2e-26 92.0 0.1 4.5e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAK66742.1 - 1.1e-19 71.0 0.2 1.1e-19 71.0 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 GAK66742.1 - 0.21 12.2 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Yae1_N PF09811.9 GAK66743.1 - 8.7e-11 41.3 5.6 1.5e-10 40.6 5.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.22 GAK66744.1 - 9.3e-13 47.8 0.8 1.7e-08 34.1 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSN8_PSD8_EIF3K PF10075.9 GAK66745.1 - 8.6e-31 106.8 0.0 9.7e-30 103.4 0.0 2.2 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family NUDIX PF00293.28 GAK66746.1 - 7.2e-25 87.5 0.0 1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L6 PF00347.23 GAK66747.1 - 1.1e-20 74.0 1.2 1.1e-07 32.4 0.1 3.2 3 0 0 3 3 3 3 Ribosomal protein L6 Lipase_GDSL_2 PF13472.6 GAK66749.1 - 0.03 14.7 0.0 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 GAK66750.1 - 5.4e-09 35.4 23.8 1.2e-08 34.3 23.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAK66750.1 - 5.9e-05 22.8 3.1 5.9e-05 22.8 3.1 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Aminotran_1_2 PF00155.21 GAK66751.1 - 8.7e-56 189.6 0.0 1.1e-55 189.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAK66751.1 - 0.0043 16.4 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 GAK66751.1 - 0.018 13.8 0.0 0.096 11.5 0.0 1.9 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.21 GAK66751.1 - 0.037 12.7 0.0 0.078 11.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 GAK66751.1 - 0.092 11.3 0.0 0.16 10.4 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DHHC PF01529.20 GAK66752.1 - 2.6e-29 102.0 0.7 4.7e-29 101.2 0.7 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase CobS_N PF12556.8 GAK66752.1 - 0.099 12.4 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal zf-tcix PF14952.6 GAK66752.1 - 0.32 10.6 2.5 0.63 9.7 2.5 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF35_N PF12172.8 GAK66752.1 - 3 7.8 7.0 9.2 6.3 7.0 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Formyl_trans_N PF00551.19 GAK66753.1 - 9.1e-18 64.6 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 GAK66753.1 - 0.026 14.7 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain GGACT PF06094.12 GAK66754.1 - 2.7e-15 57.1 0.1 5.4e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Acyltransferase PF01553.21 GAK66754.1 - 2.8e-13 49.7 0.0 9.3e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase GCIP PF13324.6 GAK66755.1 - 1.2e-09 38.2 14.0 5.9e-09 35.9 1.3 4.3 3 2 2 5 5 5 2 Grap2 and cyclin-D-interacting Aminotran_5 PF00266.19 GAK66755.1 - 2.5e-09 36.6 0.0 5.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V WW PF00397.26 GAK66756.1 - 6.9e-05 22.8 0.6 6.9e-05 22.8 0.6 2.0 2 0 0 2 2 2 1 WW domain CDC45 PF02724.14 GAK66756.1 - 0.16 10.2 7.4 0.2 9.9 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GAK66756.1 - 1.6 7.4 2.7 2.2 7.0 2.7 1.2 1 0 0 1 1 1 0 Presenilin tRNA-synt_2b PF00587.25 GAK66757.1 - 4e-36 124.6 0.0 7.2e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAK66757.1 - 3.6e-20 71.9 0.1 7.6e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 GAK66757.1 - 3.5e-14 52.6 0.0 5.4e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 TGS domain tRNA_SAD PF07973.14 GAK66757.1 - 5.7e-10 39.1 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CENP-F_N PF10481.9 GAK66758.1 - 0.05 13.2 1.1 0.067 12.8 1.1 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain PTPA PF03095.15 GAK66759.1 - 1e-101 340.4 0.0 1.2e-101 340.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein AhpC-TSA PF00578.21 GAK66761.1 - 8.9e-21 74.1 0.0 1.2e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAK66761.1 - 3.1e-10 39.9 0.0 4.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 GAK66761.1 - 0.057 13.5 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ank_4 PF13637.6 GAK66762.1 - 1.7e-17 63.6 0.4 3.4e-07 30.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK66762.1 - 4.2e-15 56.1 0.1 6.4e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAK66762.1 - 2.5e-13 49.8 0.4 1.7e-05 25.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAK66762.1 - 9.9e-13 48.1 1.3 1.2e-05 25.5 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAK66762.1 - 5.7e-12 44.7 0.6 0.0027 18.1 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat SUIM_assoc PF16619.5 GAK66763.1 - 7.6e-05 22.7 0.1 0.00014 21.8 0.1 1.5 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 GAK66763.1 - 1.3 8.2 14.5 1.4 8.0 14.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 GAK66763.1 - 3 7.4 10.7 3.7 7.1 10.7 1.1 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 GAK66764.1 - 3.7e-53 180.6 0.0 5.1e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66764.1 - 6.1e-41 140.4 0.0 9.5e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK66764.1 - 1.2e-06 27.6 0.0 3.1e-06 26.2 0.0 1.7 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAK66764.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAK66764.1 - 0.024 14.5 1.2 0.041 13.8 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family DREPP PF05558.12 GAK66764.1 - 0.18 11.6 0.5 0.31 10.9 0.5 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Haspin_kinase PF12330.8 GAK66764.1 - 0.22 10.4 0.0 2.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain LIDHydrolase PF10230.9 GAK66765.1 - 1.5e-40 139.4 0.0 2.6e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chromo PF00385.24 GAK66765.1 - 2.3e-12 46.6 1.7 4.6e-12 45.6 1.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 GAK66765.1 - 7.1e-11 42.0 0.1 3.7e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain Hydrolase_4 PF12146.8 GAK66765.1 - 8.4e-08 31.8 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK66765.1 - 6.9e-05 23.6 7.2 6.9e-05 23.6 7.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAK66765.1 - 0.0077 16.0 0.2 0.024 14.3 0.2 1.8 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 GAK66765.1 - 0.029 14.2 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 GAK66765.1 - 0.21 11.2 1.0 0.81 9.3 0.3 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Kei1 PF08552.11 GAK66766.1 - 1.3e-53 181.7 3.4 2.6e-53 180.7 3.4 1.5 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_L26 PF16906.5 GAK66766.1 - 1.4e-31 108.8 2.9 4.3e-16 59.1 0.6 2.5 2 0 0 2 2 2 2 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAK66766.1 - 4.1e-06 26.6 0.6 8.9e-06 25.5 0.6 1.6 1 0 0 1 1 1 1 KOW motif Ion_trans PF00520.31 GAK66767.1 - 2e-05 24.0 16.0 2e-05 24.0 16.0 1.9 2 0 0 2 2 2 1 Ion transport protein Ofd1_CTDD PF10637.9 GAK66768.1 - 0.21 10.9 1.8 0.29 10.5 1.8 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term LAMTOR PF15454.6 GAK66768.1 - 7.4 7.3 11.8 4.3 8.0 5.9 2.4 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Per1 PF04080.13 GAK66769.1 - 5.7e-101 337.6 1.0 7.3e-101 337.2 1.0 1.1 1 0 0 1 1 1 1 Per1-like family DUF802 PF05650.11 GAK66769.1 - 0.024 15.1 1.1 0.056 13.9 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Methyltrn_RNA_3 PF02598.17 GAK66770.1 - 6.9e-105 350.6 0.0 9.3e-105 350.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase RRM_1 PF00076.22 GAK66771.1 - 8.9e-11 41.5 0.1 2.8e-10 39.8 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 GAK66771.1 - 5.7 7.6 10.5 0.7 10.5 5.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) D123 PF07065.14 GAK66772.1 - 3.7e-92 308.8 0.0 4.3e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 GAK66772.1 - 0.004 17.2 0.3 0.0083 16.2 0.3 1.5 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 GAK66772.1 - 0.025 14.4 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 HLH PF00010.26 GAK66773.1 - 0.00027 20.8 0.2 0.00061 19.7 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.6 GAK66773.1 - 0.37 11.7 4.9 1.4 9.8 4.9 2.0 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Pkinase PF00069.25 GAK66774.1 - 1.9e-64 217.6 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66774.1 - 1.4e-34 119.6 0.0 2.2e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK66774.1 - 1.7e-07 30.9 0.0 2.9e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAK66774.1 - 3.2e-05 22.9 0.5 7.8e-05 21.6 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAK66774.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK66774.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAK66774.1 - 0.099 12.2 0.0 2.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 GAK66774.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 GAK66774.1 - 0.2 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Snf7 PF03357.21 GAK66775.1 - 1.6e-40 138.6 20.1 6.4e-40 136.6 19.1 1.9 2 0 0 2 2 2 1 Snf7 Exonuc_VII_L PF02601.15 GAK66775.1 - 0.035 13.7 6.4 0.046 13.3 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit KfrA_N PF11740.8 GAK66775.1 - 0.065 13.9 1.1 0.065 13.9 1.1 2.9 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term DUF4407 PF14362.6 GAK66775.1 - 0.15 11.4 9.3 0.014 14.8 5.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ist1 PF03398.14 GAK66775.1 - 0.28 11.1 6.3 0.41 10.6 6.3 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway TPR_MLP1_2 PF07926.12 GAK66775.1 - 1.3 9.1 13.4 3.2 7.8 6.9 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 GAK66775.1 - 1.6 9.1 8.9 5.7 7.3 2.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein GIT_CC PF16559.5 GAK66775.1 - 2.6 8.0 6.6 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PspA_IM30 PF04012.12 GAK66775.1 - 3.4 7.2 21.3 0.045 13.3 6.3 2.1 1 1 0 2 2 2 0 PspA/IM30 family COG2 PF06148.11 GAK66775.1 - 4.8 7.3 8.9 1.2 9.2 4.5 2.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CLN3 PF02487.17 GAK66776.1 - 6.7e-118 394.2 0.1 3.3e-117 391.9 0.1 1.8 1 1 0 1 1 1 1 CLN3 protein FAM53 PF15242.6 GAK66776.1 - 0.25 11.1 5.2 0.42 10.4 5.2 1.3 1 0 0 1 1 1 0 Family of FAM53 CLP1_P PF16575.5 GAK66777.1 - 4.8e-25 88.5 0.0 9e-22 77.8 0.0 2.5 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF444 PF04285.12 GAK66777.1 - 1.9 7.5 7.4 3.2 6.7 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) W2 PF02020.18 GAK66778.1 - 6.1e-15 55.1 2.2 6.1e-15 55.1 2.2 2.4 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 GAK66778.1 - 2.3e-13 49.3 3.8 2.6e-05 23.8 1.1 4.4 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 GAK66778.1 - 4.2e-09 36.4 0.0 7.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 GAK66778.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 GAK66778.1 - 1.6 8.5 11.3 0.11 12.2 1.7 3.6 2 1 3 5 5 5 0 Hexapeptide repeat of succinyl-transferase RNA_pol_Rpc4 PF05132.14 GAK66779.1 - 4.2e-32 111.6 0.2 4.2e-32 111.6 0.2 4.6 5 1 0 5 5 5 1 RNA polymerase III RPC4 PGK PF00162.19 GAK66780.1 - 3.4e-147 490.3 1.5 3.8e-147 490.2 1.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Arginosuc_synth PF00764.19 GAK66781.1 - 2e-161 537.6 0.0 2.3e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 GAK66781.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAK66781.1 - 0.013 14.3 0.0 0.032 13.0 0.0 1.6 1 1 1 2 2 2 0 tRNA methyl transferase Iso_dh PF00180.20 GAK66782.1 - 1.2e-91 307.5 0.0 1.5e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.26 GAK66784.1 - 8.7e-11 41.7 5.4 5.3e-05 23.4 0.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK66784.1 - 3.6e-08 33.6 4.2 0.0023 18.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAK66784.1 - 2e-07 31.1 4.5 1.5e-05 25.2 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAK66784.1 - 7.6e-06 26.1 1.5 0.095 13.0 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 GAK66784.1 - 0.0048 16.6 1.5 1.8 8.4 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain CHB_HEX_C_1 PF13290.6 GAK66784.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain zf-BED PF02892.15 GAK66784.1 - 0.084 12.9 0.5 3.7 7.7 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger FTZ PF03867.14 GAK66784.1 - 0.2 11.2 6.9 0.13 11.8 4.9 1.6 1 1 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region zf-C2H2_2 PF12756.7 GAK66784.1 - 0.26 11.6 0.9 5.2 7.5 0.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SUIM_assoc PF16619.5 GAK66784.1 - 0.41 10.7 14.4 1.6 8.9 9.1 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_6 PF13912.6 GAK66784.1 - 0.42 10.7 2.1 4.3 7.5 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 GAK66784.1 - 0.6 10.6 2.9 30 5.2 0.1 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 GAK66784.1 - 1.3 8.8 5.0 4.7 7.1 0.7 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 GAK66784.1 - 1.4 9.4 7.3 1.4 9.4 0.4 2.8 3 0 0 3 3 2 0 Zinc-finger of C2H2 type AAA_5 PF07728.14 GAK66788.1 - 1.2e-120 397.9 0.0 1.6e-21 76.8 0.0 9.7 8 1 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 GAK66788.1 - 1.3e-46 157.2 2.4 2e-14 53.7 0.0 5.7 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 GAK66788.1 - 9.8e-28 96.3 0.0 4.8e-27 94.1 0.0 2.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 GAK66788.1 - 7e-27 93.9 0.0 1e-06 28.6 0.0 8.1 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 GAK66788.1 - 1.9e-25 89.8 0.0 0.0063 16.9 0.0 7.3 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 GAK66788.1 - 3e-21 75.7 0.0 8.9e-05 22.6 0.0 7.4 7 0 0 7 7 6 5 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 GAK66788.1 - 3.1e-20 73.3 37.5 0.00032 21.1 0.9 11.2 8 3 0 8 8 8 6 AAA ATPase domain AAA_7 PF12775.7 GAK66788.1 - 3.8e-20 72.2 1.0 0.00022 20.8 0.0 7.1 7 0 0 7 7 7 2 P-loop containing dynein motor region AAA_22 PF13401.6 GAK66788.1 - 1.7e-19 70.4 1.5 0.042 14.1 0.0 8.8 8 0 0 8 8 7 4 AAA domain AAA_18 PF13238.6 GAK66788.1 - 6.3e-18 65.6 0.0 0.11 13.1 0.0 7.3 6 0 0 6 6 6 4 AAA domain AAA_6 PF12774.7 GAK66788.1 - 3e-17 62.6 0.0 0.0091 15.0 0.2 8.2 9 0 0 9 9 9 3 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 GAK66788.1 - 7.3e-16 58.5 9.0 0.022 14.5 0.0 8.8 7 2 0 7 7 7 3 AAA domain ABC_tran PF00005.27 GAK66788.1 - 1e-15 58.4 0.2 0.17 12.4 0.0 6.9 6 0 0 6 6 6 3 ABC transporter AAA_33 PF13671.6 GAK66788.1 - 5.8e-15 55.7 7.3 0.038 14.2 0.1 8.5 9 0 0 9 9 6 3 AAA domain TsaE PF02367.17 GAK66788.1 - 3.7e-13 49.6 6.9 0.31 11.1 0.2 6.7 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAK66788.1 - 1.8e-12 47.3 0.0 0.076 12.7 0.0 6.2 6 0 0 6 6 6 2 Sigma-54 interaction domain T2SSE PF00437.20 GAK66788.1 - 3.8e-11 42.6 5.6 0.056 12.5 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein Zeta_toxin PF06414.12 GAK66788.1 - 2.1e-10 40.2 5.7 0.57 9.4 0.1 7.6 7 1 0 7 7 7 2 Zeta toxin AAA_29 PF13555.6 GAK66788.1 - 3.7e-10 39.4 3.2 0.47 10.2 0.1 6.1 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_28 PF13521.6 GAK66788.1 - 4.5e-10 40.0 9.6 0.16 12.2 0.1 7.6 7 0 0 7 7 6 3 AAA domain RNA_helicase PF00910.22 GAK66788.1 - 7e-10 39.3 0.5 2.6 8.5 0.0 6.6 6 0 0 6 6 6 1 RNA helicase Mg_chelatase PF01078.21 GAK66788.1 - 1.8e-09 37.3 4.7 0.23 10.8 0.2 7.1 8 0 0 8 8 7 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 GAK66788.1 - 3e-09 37.1 1.6 0.13 12.4 0.0 6.2 6 0 0 6 6 5 2 Sigma-54 interaction domain NACHT PF05729.12 GAK66788.1 - 3.7e-09 36.7 4.6 0.13 12.2 0.0 6.4 5 0 0 5 5 5 1 NACHT domain AAA_25 PF13481.6 GAK66788.1 - 4.2e-09 36.3 8.2 0.05 13.2 0.0 6.9 6 0 0 6 6 6 2 AAA domain AAA_14 PF13173.6 GAK66788.1 - 1.2e-08 35.0 0.0 0.022 14.8 0.0 6.3 7 0 0 7 7 5 1 AAA domain AAA_19 PF13245.6 GAK66788.1 - 1.6e-07 31.7 11.1 0.75 10.1 0.1 7.6 7 1 0 7 7 6 1 AAA domain Rad17 PF03215.15 GAK66788.1 - 2.2e-07 31.0 2.4 3.3 7.6 0.0 5.8 6 0 0 6 6 6 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 GAK66788.1 - 2.4e-07 30.8 3.6 4.6 7.1 0.1 5.6 5 0 0 5 5 5 0 RsgA GTPase DUF815 PF05673.13 GAK66788.1 - 1.4e-06 27.7 0.6 0.22 10.7 0.0 5.0 6 0 0 6 6 5 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAK66788.1 - 2.1e-06 27.6 4.1 2.4 7.9 0.0 7.0 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAK66788.1 - 3.1e-06 27.1 1.0 3 7.5 0.0 5.6 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_8 PF12780.7 GAK66788.1 - 5.5e-06 25.9 0.1 0.32 10.3 0.0 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 MMR_HSR1 PF01926.23 GAK66788.1 - 8.3e-06 25.9 0.8 1.3 9.2 0.0 5.8 6 0 0 6 6 5 1 50S ribosome-binding GTPase CPT PF07931.12 GAK66788.1 - 9.9e-06 25.5 3.6 3.5 7.4 0.0 6.8 8 0 0 8 8 7 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 GAK66788.1 - 1.5e-05 24.8 0.8 6.8 6.4 0.1 5.1 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 GAK66788.1 - 2e-05 24.2 4.1 10 5.7 0.1 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 GAK66788.1 - 2.4e-05 23.9 0.0 12 5.3 0.0 6.2 7 0 0 7 7 5 0 Bacterial TniB protein SRP54 PF00448.22 GAK66788.1 - 3.1e-05 23.7 2.3 1.6 8.3 0.1 4.9 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain AAA_21 PF13304.6 GAK66788.1 - 4.8e-05 23.3 0.6 0.47 10.2 0.0 5.4 5 0 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 GAK66788.1 - 6.6e-05 22.7 0.8 21 4.8 0.0 6.0 7 0 0 7 7 5 0 AAA domain Roc PF08477.13 GAK66788.1 - 0.00017 21.8 1.3 23 5.2 0.0 5.7 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 GAK66788.1 - 0.00029 20.9 0.1 20 5.2 0.1 4.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Cytidylate_kin PF02224.18 GAK66788.1 - 0.00068 19.4 1.6 18 5.0 0.0 5.2 5 0 0 5 5 5 0 Cytidylate kinase NTPase_1 PF03266.15 GAK66788.1 - 0.0015 18.5 4.0 3.4 7.5 0.0 5.3 6 0 0 6 6 4 0 NTPase ATP_bind_1 PF03029.17 GAK66788.1 - 0.0029 17.4 5.1 25 4.6 0.0 5.2 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein dNK PF01712.19 GAK66788.1 - 0.011 15.5 1.7 19 5.0 0.0 5.3 6 0 0 6 6 6 0 Deoxynucleoside kinase IPT PF01745.16 GAK66788.1 - 0.012 15.0 0.3 19 4.6 0.0 4.0 4 0 0 4 4 4 0 Isopentenyl transferase PhoH PF02562.16 GAK66788.1 - 0.034 13.6 1.8 17 4.8 0.0 4.2 4 0 0 4 4 4 0 PhoH-like protein ATPase_2 PF01637.18 GAK66788.1 - 0.04 13.8 0.0 12 5.8 0.0 4.1 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 GAK66788.1 - 0.052 12.7 2.7 3.5 6.7 0.1 4.1 5 0 0 5 5 5 0 TIP49 P-loop domain AAA_15 PF13175.6 GAK66788.1 - 0.062 13.0 0.0 64 3.1 0.0 4.2 4 0 0 4 4 4 0 AAA ATPase domain Ploopntkinase3 PF18751.1 GAK66788.1 - 0.07 13.0 0.2 41 4.0 0.0 4.2 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 GAK66788.1 - 0.13 11.6 3.7 0.36 10.2 0.0 3.5 4 0 0 4 4 3 0 Chromatin associated protein KTI12 PRK PF00485.18 GAK66788.1 - 0.15 11.8 1.1 69 3.1 0.0 4.2 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 GAK66788.1 - 0.85 9.7 2.8 63 3.5 0.1 5.2 4 0 0 4 4 3 0 Helicase HerA, central domain CbiA PF01656.23 GAK66788.1 - 1.1 9.4 6.4 14 5.8 0.2 4.6 5 0 0 5 5 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 GAK66788.1 - 1.2 8.5 5.6 19 4.5 0.0 4.7 5 0 0 5 5 4 0 FtsK/SpoIIIE family MeaB PF03308.16 GAK66788.1 - 1.2 8.1 7.6 16 4.3 0.1 4.5 5 0 0 5 5 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 GAK66788.1 - 2.5 8.6 0.0 2.5 8.6 0.0 9.6 9 1 0 9 9 7 0 AAA domain G-alpha PF00503.20 GAK66788.1 - 4.5 6.3 5.9 11 5.1 0.0 3.6 5 0 0 5 5 3 0 G-protein alpha subunit TFIIS_C PF01096.18 GAK66789.1 - 3.9e-17 61.8 5.8 3.7e-16 58.7 0.4 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAK66789.1 - 6.3e-08 32.4 8.8 0.00016 21.5 0.5 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 GAK66789.1 - 4.5e-05 23.4 5.7 0.059 13.4 0.1 3.0 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 GAK66789.1 - 0.00011 21.7 9.0 0.025 14.1 0.6 2.7 2 1 0 2 2 2 2 TFIIB zinc-binding IBR PF01485.21 GAK66789.1 - 0.0046 17.1 4.6 1.5 9.1 1.3 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain zf-TFIIB PF13453.6 GAK66789.1 - 0.0072 15.6 4.8 0.016 14.6 0.8 2.5 2 0 0 2 2 2 1 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.11 GAK66789.1 - 0.0092 15.9 5.9 0.25 11.3 0.1 2.8 2 1 0 2 2 2 1 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 GAK66789.1 - 0.014 14.8 19.4 0.16 11.5 4.3 4.0 3 1 0 3 3 3 0 zinc-ribbon domain TackOD1 PF18551.1 GAK66789.1 - 0.014 15.0 2.9 0.24 11.0 0.1 2.5 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 CpXC PF14353.6 GAK66789.1 - 0.019 15.0 6.7 19 5.3 0.0 3.9 3 1 1 4 4 4 0 CpXC protein Baculo_LEF5_C PF11792.8 GAK66789.1 - 0.046 13.4 0.2 0.17 11.6 0.2 2.1 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain zf-NADH-PPase PF09297.11 GAK66789.1 - 0.047 13.4 10.0 4.5 7.0 0.1 4.0 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf-ISL3 PF14690.6 GAK66789.1 - 0.052 14.2 6.8 23 5.8 0.1 4.0 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prok-RING_1 PF14446.6 GAK66789.1 - 0.074 13.0 9.0 0.8 9.7 1.2 3.3 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 DUF35_N PF12172.8 GAK66789.1 - 0.098 12.6 7.8 9.5 6.2 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Terminase_GpA PF05876.12 GAK66789.1 - 0.1 11.1 0.5 0.33 9.4 0.2 1.9 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-H2C2_2 PF13465.6 GAK66789.1 - 0.1 13.0 0.1 0.1 13.0 0.1 3.7 5 0 0 5 5 4 0 Zinc-finger double domain zf-RING_7 PF02591.15 GAK66789.1 - 0.11 12.7 8.0 0.22 11.8 0.1 3.8 5 0 0 5 5 4 0 C4-type zinc ribbon domain zf-IS66 PF13005.7 GAK66789.1 - 0.15 12.5 9.9 1.8 9.0 0.0 3.7 4 0 0 4 4 3 0 zinc-finger binding domain of transposase IS66 zf_C2H2_10 PF18414.1 GAK66789.1 - 0.16 11.5 5.8 1.1 8.9 0.9 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger NOB1_Zn_bind PF08772.11 GAK66789.1 - 0.17 12.1 7.8 6.2 7.1 0.0 3.5 3 1 1 4 4 3 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 GAK66789.1 - 0.17 11.7 19.7 1.1 9.1 0.6 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 GAK66789.1 - 0.19 11.7 10.3 4.7 7.3 2.5 3.4 2 2 0 2 2 2 0 Transposase zinc-ribbon domain DUF1610 PF07754.11 GAK66789.1 - 0.34 10.9 0.2 0.34 10.9 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) eIF-5_eIF-2B PF01873.17 GAK66789.1 - 0.44 10.4 3.8 1.9 8.4 0.4 2.3 2 1 0 2 2 2 0 Domain found in IF2B/IF5 Ribosomal_S27e PF01667.17 GAK66789.1 - 0.58 9.9 7.2 3.5 7.4 0.0 3.6 3 1 1 4 4 4 0 Ribosomal protein S27 Ogr_Delta PF04606.12 GAK66789.1 - 0.58 10.2 9.9 8.4 6.5 2.1 3.6 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger zf-LITAF-like PF10601.9 GAK66789.1 - 0.58 10.5 5.1 25 5.2 0.1 3.6 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Nop10p PF04135.12 GAK66789.1 - 0.64 10.1 5.8 1.3 9.1 0.1 3.3 3 1 1 4 4 3 0 Nucleolar RNA-binding protein, Nop10p family DUF3268 PF11672.8 GAK66789.1 - 0.71 10.2 3.2 2 8.8 0.4 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 GAK66789.1 - 0.71 10.0 16.3 12 6.1 0.8 3.9 2 2 1 4 4 4 0 Zinc ribbon domain DUF2752 PF10825.8 GAK66789.1 - 0.76 9.9 9.9 4.3 7.5 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2752) zinc_ribbon_5 PF13719.6 GAK66789.1 - 0.86 9.4 9.9 0.94 9.3 0.4 3.4 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 GAK66789.1 - 0.99 9.4 12.5 14 5.7 0.2 4.2 3 1 1 4 4 4 0 zinc-ribbon domain HalOD2 PF18547.1 GAK66789.1 - 1.1 9.2 6.7 8.6 6.4 0.0 3.7 3 1 0 3 3 3 0 Halobacterial output domain 2 zf-ACC PF17848.1 GAK66789.1 - 1.4 9.0 16.3 8.8 6.5 0.0 4.2 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain UPF0547 PF10571.9 GAK66789.1 - 2.2 8.4 18.4 0.62 10.2 0.5 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DUF3797 PF12677.7 GAK66789.1 - 2.4 8.1 13.9 21 5.1 5.4 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3797) Zn_ribbon_recom PF13408.6 GAK66789.1 - 2.6 8.6 7.3 13 6.4 0.1 3.5 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain Zn_ribbon_SprT PF17283.2 GAK66789.1 - 3 7.8 6.7 36 4.4 0.3 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DNA_ligase_ZBD PF03119.16 GAK66789.1 - 3.4 7.8 9.6 6.1 7.0 0.1 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C2H2 PF00096.26 GAK66789.1 - 3.7 8.2 10.4 1.3 9.6 1.3 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.6 GAK66789.1 - 4.8 7.2 13.1 15 5.6 3.3 3.8 2 2 0 2 2 2 0 Nudix N-terminal A2L_zn_ribbon PF08792.10 GAK66789.1 - 5.2 6.9 14.2 1.9 8.3 0.2 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain YhfH PF14149.6 GAK66789.1 - 5.6 7.0 10.2 46 4.1 0.1 4.0 4 0 0 4 4 4 0 YhfH-like protein DNA_RNApol_7kD PF03604.13 GAK66789.1 - 7.6 6.3 12.4 5.1 6.9 1.5 3.7 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.6 GAK66789.1 - 7.9 6.7 13.6 2.2 8.5 4.0 3.2 2 2 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 ATG7_N PF16420.5 GAK66790.1 - 7.8e-91 304.8 0.0 1.2e-90 304.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 GAK66790.1 - 3.8e-45 154.2 0.0 5.7e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 GAK66790.1 - 0.0098 16.0 0.0 0.08 13.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase mRNA_cap_enzyme PF01331.19 GAK66791.1 - 1.2e-48 165.5 0.0 1.5e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GAK66791.1 - 6.1e-28 97.6 0.0 8.7e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 GAK66791.1 - 0.00026 20.7 0.0 0.027 14.1 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Proteasome PF00227.26 GAK66792.1 - 2e-48 164.4 0.2 2.7e-48 164.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit CYSTM PF12734.7 GAK66792.1 - 0.025 14.9 22.7 0.025 14.9 22.7 3.3 2 2 0 2 2 2 0 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 GAK66792.1 - 0.59 10.1 10.4 0.98 9.4 10.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cellulase PF00150.18 GAK66794.1 - 4.3e-11 42.8 4.8 1.2e-10 41.3 4.6 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SIR2 PF02146.17 GAK66795.1 - 9.3e-35 120.1 0.0 5.3e-34 117.7 0.0 2.2 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAK66795.1 - 0.0019 18.0 0.0 0.088 12.5 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Alpha-L-AF_C PF06964.12 GAK66797.1 - 1.5e-27 96.8 0.0 2.1e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain OrsD PF12013.8 GAK66798.1 - 4.7e-08 33.5 4.5 6.1e-08 33.1 2.9 1.9 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_7 PF15269.6 GAK66798.1 - 0.019 15.0 0.4 0.038 14.1 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger zf-C2H2 PF00096.26 GAK66798.1 - 0.12 12.9 5.5 0.38 11.3 5.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAK66798.1 - 0.18 12.2 1.5 0.23 11.8 0.5 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAK66798.1 - 1 9.7 8.9 1.7 9.0 5.9 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAK66798.1 - 1.1 10.3 8.5 0.7 10.9 4.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 GAK66798.1 - 1.5 9.3 4.8 0.91 10.0 1.9 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Orbi_VP6 PF01516.16 GAK66799.1 - 1.3 8.4 16.1 2.3 7.7 6.0 2.1 1 1 1 2 2 2 0 Orbivirus helicase VP6 Bac_rhamnosid_C PF17390.2 GAK66800.1 - 1.3e-06 28.1 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 GAK66800.1 - 8.4e-06 25.3 0.0 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid PF05592.11 GAK66800.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain RTA1 PF04479.13 GAK66801.1 - 1.6e-39 135.7 14.9 2.8e-32 112.0 4.1 2.5 3 0 0 3 3 3 2 RTA1 like protein 2OG-FeII_Oxy_2 PF13532.6 GAK66801.1 - 8.7e-10 39.1 0.0 1.2e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2516 PF10724.9 GAK66801.1 - 1.4 9.2 6.3 0.88 9.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) Pribosyltran PF00156.27 GAK66802.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain EC042_2821 PF18740.1 GAK66802.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 EC042_2821-lke REase Vps51 PF08700.11 GAK66803.1 - 2.1e-16 59.8 0.1 4.1e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 GAK66803.1 - 0.078 11.6 0.1 0.099 11.3 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family COG5 PF10392.9 GAK66803.1 - 0.12 12.5 1.5 0.21 11.8 1.5 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FlgN PF05130.12 GAK66803.1 - 0.13 12.8 0.2 0.39 11.2 0.1 1.8 2 0 0 2 2 2 0 FlgN protein Usp PF00582.26 GAK66804.1 - 2e-23 83.5 0.5 2e-23 83.5 0.5 2.8 2 1 0 2 2 2 1 Universal stress protein family THOC2_N PF16134.5 GAK66806.1 - 8.2e-168 559.9 0.0 8.2e-168 559.9 0.0 2.7 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 GAK66806.1 - 1.2e-94 317.0 0.0 1.2e-94 317.0 0.0 1.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 GAK66806.1 - 1.3e-31 108.5 0.1 4.4e-31 106.8 0.1 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit RhoGEF PF00621.20 GAK66807.1 - 1.6e-30 106.7 0.0 2.9e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain RRM_1 PF00076.22 GAK66808.1 - 3.6e-32 110.0 5.3 4.9e-17 61.5 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK66808.1 - 0.00031 20.3 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK66808.1 - 0.13 12.4 0.0 10 6.3 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif LtrA PF06772.11 GAK66809.1 - 8.7e-19 67.9 22.5 8.7e-19 67.9 22.5 2.7 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Tmemb_161AB PF10268.9 GAK66809.1 - 0.024 13.3 0.2 0.041 12.5 0.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB RabGAP-TBC PF00566.18 GAK66810.1 - 6.8e-52 176.2 0.0 1.2e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PPR_2 PF13041.6 GAK66811.1 - 7e-17 61.4 0.0 0.00052 20.2 0.0 5.1 5 0 0 5 5 5 3 PPR repeat family PPR_1 PF12854.7 GAK66811.1 - 1.5e-15 56.6 1.5 1.4e-06 27.9 0.0 3.7 3 0 0 3 3 3 3 PPR repeat PPR PF01535.20 GAK66811.1 - 6.3e-09 35.5 4.1 0.0018 18.4 0.0 5.1 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 GAK66811.1 - 0.00026 21.0 0.1 0.096 12.8 0.0 3.7 4 0 0 4 4 4 1 Pentatricopeptide repeat domain ABC2_membrane PF01061.24 GAK66812.1 - 1.3e-80 269.7 64.0 2.9e-42 144.5 25.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAK66812.1 - 2.2e-36 125.4 0.0 8e-18 65.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 GAK66812.1 - 1.4e-23 82.6 0.2 1.5e-20 72.9 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAK66812.1 - 7.2e-10 39.4 1.2 1.4e-09 38.4 0.3 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 GAK66812.1 - 2.6e-06 27.6 0.7 0.011 15.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 GAK66812.1 - 2.6e-05 24.2 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAK66812.1 - 3.3e-05 23.5 0.2 0.02 14.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAK66812.1 - 9.5e-05 22.8 0.1 0.24 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 GAK66812.1 - 0.00011 21.4 50.9 0.00013 21.2 20.0 3.6 3 1 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAK66812.1 - 0.00027 20.9 0.2 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 GAK66812.1 - 0.00088 18.8 0.1 0.01 15.3 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAK66812.1 - 0.00091 19.5 0.3 0.91 9.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAK66812.1 - 0.0011 18.6 0.2 0.043 13.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAK66812.1 - 0.0024 18.4 1.5 0.42 11.2 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 GAK66812.1 - 0.017 15.4 0.3 0.32 11.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAK66812.1 - 0.021 14.9 0.7 8.9 6.4 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 GAK66812.1 - 0.021 14.4 1.3 0.82 9.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAK66812.1 - 0.026 14.5 0.7 4.9 7.0 0.2 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 GAK66812.1 - 0.036 14.4 0.9 7.6 7.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 GAK66812.1 - 0.037 13.7 0.5 4 7.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAK66812.1 - 0.037 13.3 0.6 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 GAK66812.1 - 0.15 11.4 0.1 3.7 6.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 GAK66812.1 - 3.4 8.1 6.9 10 6.6 0.1 3.4 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 GAK66812.1 - 6.7 7.2 8.8 0.61 10.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain DUF1440 PF07274.12 GAK66812.1 - 9.2 6.6 8.0 21 5.5 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) Complex1_LYR PF05347.15 GAK66813.1 - 2.2e-07 30.8 4.4 4e-07 30.0 4.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxogl_dehyd_N PF16078.5 GAK66813.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus His_Phos_1 PF00300.22 GAK66815.1 - 3.8e-14 52.8 0.0 6.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3552 PF12072.8 GAK66815.1 - 0.24 10.8 8.9 0.081 12.3 6.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 GAK66815.1 - 3.4 6.5 7.4 2.8 6.7 6.1 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein HhH-GPD PF00730.25 GAK66816.1 - 3.6e-08 33.8 0.0 4.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Palm_thioest PF02089.15 GAK66817.1 - 5.9e-79 265.3 0.0 7.4e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase FSH1 PF03959.13 GAK66817.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 GAK66817.1 - 0.032 13.9 0.1 0.11 12.1 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold SfLAP PF11139.8 GAK66817.1 - 0.1 12.0 2.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein Clat_adaptor_s PF01217.20 GAK66818.1 - 1.4e-17 64.0 0.1 2.1e-15 56.9 0.1 2.2 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 GAK66819.1 - 6.8e-75 251.8 0.0 9e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66819.1 - 1.5e-43 148.9 0.0 2.1e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK66819.1 - 5.4e-12 45.6 0.0 8.6e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAK66819.1 - 0.0079 15.2 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAK66819.1 - 0.0079 15.6 0.1 0.042 13.2 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.21 GAK66820.1 - 3.5e-18 65.8 0.0 7.5e-11 41.8 0.0 3.0 3 0 0 3 3 3 3 Aldo/keto reductase family Chitin_synth_1 PF01644.17 GAK66821.1 - 7.6e-70 234.1 0.0 1.1e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAK66821.1 - 7.3e-28 96.3 0.0 1.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAK66821.1 - 7.9e-26 90.8 0.2 3.8e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAK66821.1 - 1.7e-11 44.4 6.0 1.1e-09 38.5 0.1 2.5 1 1 1 2 2 2 2 Glycosyl transferase family group 2 RabGAP-TBC PF00566.18 GAK66822.1 - 4.4e-19 69.0 0.4 2.3e-15 56.8 0.5 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MFS_1 PF07690.16 GAK66823.1 - 1.5e-24 86.6 33.3 2.1e-24 86.1 33.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK66823.1 - 1 8.2 22.6 2.8 6.7 20.5 2.2 1 1 0 1 1 1 0 Sugar (and other) transporter NifU_N PF01592.16 GAK66828.1 - 5.5e-54 181.8 0.4 8.3e-54 181.2 0.1 1.5 2 0 0 2 2 2 1 NifU-like N terminal domain Ribosomal_L11 PF00298.19 GAK66829.1 - 6.5e-26 90.6 2.0 1e-25 90.0 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAK66829.1 - 6.5e-23 80.4 0.8 1.7e-22 79.0 0.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain NUC153 PF08159.12 GAK66830.1 - 1.9e-10 40.4 1.0 3.3e-10 39.6 1.0 1.4 1 0 0 1 1 1 1 NUC153 domain TFIIA PF03153.13 GAK66830.1 - 0.11 12.5 13.5 0.17 11.8 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Proteasome PF00227.26 GAK66831.1 - 2e-60 203.5 0.0 4.6e-60 202.4 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 GAK66831.1 - 2e-09 36.9 0.0 7.5e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RabGAP-TBC PF00566.18 GAK66832.1 - 7.8e-17 61.7 0.0 1.7e-16 60.6 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FlpD PF02662.16 GAK66832.1 - 0.22 11.5 0.0 0.57 10.2 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Ras PF00071.22 GAK66833.1 - 6.3e-46 155.9 0.6 7.9e-46 155.6 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK66833.1 - 1.2e-15 57.8 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK66833.1 - 1.9e-06 27.4 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK66833.1 - 6.9e-05 22.9 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK66833.1 - 0.0019 17.8 0.4 0.007 15.9 0.2 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAK66833.1 - 0.0028 17.1 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAK66833.1 - 0.0075 16.2 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAK66833.1 - 0.015 14.8 0.1 0.17 11.4 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Rpr2 PF04032.16 GAK66834.1 - 3.4e-12 46.5 1.7 5.1e-12 45.9 0.3 2.0 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4874 PF16173.5 GAK66834.1 - 0.058 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Glyco_hydro_cc PF11790.8 GAK66835.1 - 3.1e-57 193.9 10.2 4.7e-57 193.3 10.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Apt1 PF10351.9 GAK66835.1 - 0.052 12.4 6.8 0.06 12.2 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4897 PF16238.5 GAK66835.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) NPR3 PF03666.13 GAK66835.1 - 0.1 11.4 3.1 0.13 11.0 3.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 GAK66835.1 - 0.2 10.9 1.5 0.23 10.6 1.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tub_N PF16322.5 GAK66835.1 - 0.2 12.0 11.8 0.32 11.4 11.7 1.4 1 1 0 1 1 1 0 Tubby N-terminal SR-25 PF10500.9 GAK66835.1 - 0.34 10.5 31.8 0.54 9.8 31.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 GAK66835.1 - 0.79 8.4 8.8 1.3 7.7 8.8 1.2 1 0 0 1 1 1 0 Presenilin AF-4 PF05110.13 GAK66835.1 - 3.3 5.7 30.6 4.9 5.1 30.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 GAK66835.1 - 3.5 6.1 13.7 5.1 5.5 13.7 1.2 1 0 0 1 1 1 0 Macoilin family SpoIIIAH PF12685.7 GAK66835.1 - 3.8 7.3 9.9 7.5 6.3 9.9 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Peroxin-3 PF04882.12 GAK66835.1 - 4.6 6.1 8.8 7 5.5 8.8 1.2 1 0 0 1 1 1 0 Peroxin-3 SOG2 PF10428.9 GAK66835.1 - 5.7 6.0 15.1 8.3 5.5 15.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3245 PF11595.8 GAK66835.1 - 9.2 6.7 17.0 0.22 12.0 10.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF3818 PF12825.7 GAK66838.1 - 2.9e-64 217.2 0.0 4.2e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 GAK66838.1 - 0.00033 20.6 0.3 0.0013 18.7 0.3 1.8 1 1 0 1 1 1 1 PX-associated Peptidase_C13 PF01650.18 GAK66842.1 - 2.3e-40 138.7 0.0 3.1e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 GAK66842.1 - 0.042 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Mid domain of argonaute DUF4447 PF14590.6 GAK66842.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4447) RRM_1 PF00076.22 GAK66843.1 - 2.2e-27 94.7 0.0 5.3e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAK66843.1 - 0.0026 17.8 1.1 0.49 10.5 0.0 2.6 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 GAK66843.1 - 0.0031 17.5 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 GAK66843.1 - 0.027 14.6 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 GAK66843.1 - 0.11 12.5 0.0 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SH3_1 PF00018.28 GAK66844.1 - 3.9e-23 80.8 0.0 2.5e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAK66844.1 - 1.1e-13 50.6 0.0 5.9e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 GAK66844.1 - 8.3e-13 48.0 0.0 2.5e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 GAK66844.1 - 6.3e-09 35.8 0.0 2.1e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 PX domain Adap_comp_sub PF00928.21 GAK66845.1 - 7.3e-43 146.8 0.0 9.7e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAK66845.1 - 0.0023 17.9 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DNA_RNApol_7kD PF03604.13 GAK66846.1 - 4.6e-07 29.4 1.8 8.4e-07 28.6 1.8 1.4 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2838 PF10998.8 GAK66847.1 - 1.2e-35 122.1 15.6 2.6e-34 117.8 9.6 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF2838) DUF4618 PF15397.6 GAK66847.1 - 0.013 14.9 1.7 0.025 14.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Tho2 PF11262.8 GAK66847.1 - 0.14 11.3 1.3 2.2 7.4 1.2 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF1640 PF07798.11 GAK66847.1 - 0.17 11.9 4.4 0.26 11.3 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) BPS1 PF05633.11 GAK66847.1 - 0.34 9.9 3.5 0.098 11.7 0.4 1.6 2 0 0 2 2 2 0 Protein BYPASS1-related DUF349 PF03993.12 GAK66847.1 - 0.34 11.2 3.8 0.9 9.9 3.8 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Seryl_tRNA_N PF02403.22 GAK66847.1 - 3.9 7.7 10.0 0.34 11.2 5.1 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HSCB_C PF07743.13 GAK66847.1 - 6.1 7.4 9.2 1 9.9 2.1 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain BOP1NT PF08145.12 GAK66848.1 - 3.3e-106 355.0 3.7 5e-106 354.4 3.7 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 GAK66848.1 - 1.9e-21 76.0 10.6 1.9e-07 31.7 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK66848.1 - 1.1e-05 25.6 0.4 0.062 13.6 0.0 4.9 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Actin PF00022.19 GAK66849.1 - 1e-114 383.3 0.0 1.7e-114 382.6 0.0 1.3 1 1 0 1 1 1 1 Actin adh_short_C2 PF13561.6 GAK66850.1 - 4.1e-56 190.1 0.5 5.1e-56 189.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK66850.1 - 1.2e-45 155.4 3.3 1.6e-45 155.0 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK66850.1 - 8e-17 61.7 2.1 1.3e-16 61.1 1.1 1.7 1 1 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 GAK66850.1 - 5.1e-05 22.8 0.1 6.4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAK66850.1 - 0.00066 19.2 0.5 0.0011 18.5 0.5 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SBP_bac_5 PF00496.22 GAK66850.1 - 0.00074 18.6 0.0 0.0013 17.8 0.0 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Polysacc_synt_2 PF02719.15 GAK66850.1 - 0.0021 17.3 0.4 0.0029 16.8 0.4 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 GAK66850.1 - 0.0068 16.3 0.4 1.1 9.1 0.7 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAK66850.1 - 0.019 15.2 0.3 0.034 14.4 0.3 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 GAK66850.1 - 0.048 14.3 1.4 16 6.2 0.0 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent OAM_dimer PF16554.5 GAK66850.1 - 0.075 13.5 0.1 4.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase CoA_binding PF02629.19 GAK66850.1 - 0.1 13.3 0.6 0.39 11.4 0.3 2.0 2 0 0 2 2 2 0 CoA binding domain Halogen_Hydrol PF10112.9 GAK66850.1 - 0.2 11.7 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Rot1 PF10681.9 GAK66852.1 - 8.1e-45 152.9 0.1 1e-44 152.6 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal FixS PF03597.15 GAK66852.1 - 0.17 11.6 1.2 0.36 10.6 1.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type SKN1 PF03935.15 GAK66853.1 - 6.1e-196 651.7 0.7 7.8e-196 651.3 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAK66853.1 - 7.3e-05 22.3 0.4 0.056 12.9 0.0 3.0 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 DAO PF01266.24 GAK66855.1 - 2e-23 83.6 0.3 3.3e-22 79.6 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK66855.1 - 0.011 15.0 0.1 0.069 12.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK66855.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK66855.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 GAK66855.1 - 0.021 15.1 0.1 0.046 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAK66855.1 - 0.071 12.3 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 GAK66855.1 - 0.091 13.2 0.0 0.8 10.2 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding 2OG-FeII_Oxy PF03171.20 GAK66856.1 - 2.2e-23 82.6 0.0 4e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAK66856.1 - 2.9e-18 66.7 0.0 4.7e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PMP1_2 PF08114.11 GAK66857.1 - 0.00094 18.9 0.5 0.0016 18.1 0.5 1.3 1 0 0 1 1 1 1 ATPase proteolipid family FeoB_associated PF12669.7 GAK66857.1 - 0.27 11.7 0.5 0.52 10.8 0.5 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF262 PF03235.14 GAK66858.1 - 5.6e-13 49.6 0.0 1.1e-12 48.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 Pkinase PF00069.25 GAK66859.1 - 8.5e-74 248.2 0.0 1.1e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66859.1 - 1e-30 106.9 0.0 1.6e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK66859.1 - 1.7e-11 44.0 0.1 0.011 15.0 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 GAK66859.1 - 0.0018 17.1 0.0 0.004 16.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAK66859.1 - 0.052 12.9 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK66859.1 - 0.15 12.0 0.0 1.2 8.9 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Sedlin_N PF04628.13 GAK66860.1 - 5.5e-31 107.4 0.1 1.8e-27 96.0 0.0 2.0 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAK66860.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.6 1 1 0 1 1 1 1 Sybindin-like family Avl9 PF09794.9 GAK66860.1 - 0.099 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 DUF508 PF04370.12 GAK66860.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF508) bZIP_1 PF00170.21 GAK66861.1 - 1e-07 31.9 17.2 1.8e-07 31.2 17.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAK66861.1 - 0.014 15.5 24.1 0.15 12.1 12.7 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DNA_Packaging_2 PF11123.8 GAK66861.1 - 0.017 15.3 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 DNA packaging protein eIF3_subunit PF08597.10 GAK66861.1 - 0.066 13.1 3.1 0.096 12.6 3.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit bZIP_Maf PF03131.17 GAK66861.1 - 0.096 13.2 18.4 0.42 11.2 18.7 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.11 GAK66861.1 - 0.17 12.3 0.5 0.36 11.2 0.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 GAK66861.1 - 0.2 12.1 5.8 0.3 11.4 5.8 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4239 PF14023.6 GAK66861.1 - 0.26 11.0 0.9 0.35 10.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF16 PF01519.16 GAK66861.1 - 0.34 11.4 3.0 0.49 10.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 GAK66861.1 - 0.38 10.8 11.3 4.8 7.2 11.9 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHE3 PF17078.5 GAK66861.1 - 0.42 10.3 6.7 0.57 9.8 6.7 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 GAK66861.1 - 1.4 9.0 8.4 2 8.5 8.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 GAK66861.1 - 2.4 6.0 3.1 3 5.7 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 GAK66861.1 - 7 5.1 5.8 9.5 4.6 5.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GTP_EFTU PF00009.27 GAK66862.1 - 5e-45 153.4 0.0 7.9e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAK66862.1 - 2.6e-34 117.9 0.0 2.6e-34 117.9 0.0 2.4 4 0 0 4 4 4 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAK66862.1 - 1.8e-10 41.1 0.7 4.1e-10 39.9 0.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAK66862.1 - 0.0014 18.6 0.0 0.0056 16.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAK66862.1 - 0.1 12.5 0.4 0.36 10.8 0.4 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DAD PF02109.16 GAK66863.1 - 3.7e-47 159.1 1.0 4.3e-47 158.9 1.0 1.0 1 0 0 1 1 1 1 DAD family Rho_GDI PF02115.17 GAK66864.1 - 5e-68 228.7 0.0 5.8e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.15 GAK66864.1 - 0.17 12.3 0.0 1.3 9.5 0.0 2.2 1 1 0 1 1 1 0 ML domain DUF1640 PF07798.11 GAK66865.1 - 4.1e-61 206.1 1.6 7e-61 205.3 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) UbiA PF01040.18 GAK66865.1 - 2.7e-52 177.6 27.4 5.3e-52 176.6 27.4 1.5 1 0 0 1 1 1 1 UbiA prenyltransferase family TauD PF02668.16 GAK66865.1 - 6.1e-51 173.8 1.2 2.2e-50 171.9 1.2 2.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu_amine_oxidN1 PF07833.11 GAK66865.1 - 0.023 15.2 0.1 0.05 14.1 0.1 1.6 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain DUF971 PF06155.12 GAK66865.1 - 0.099 13.3 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Pyr_redox_2 PF07992.14 GAK66868.1 - 5.4e-36 124.3 1.0 5.1e-34 117.8 0.2 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK66868.1 - 1.1e-14 54.8 0.2 1.5e-10 41.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK66868.1 - 6.8e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK66868.1 - 3.4e-05 23.6 0.5 0.022 14.3 0.3 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAK66868.1 - 0.00053 19.2 0.4 0.0014 17.8 0.1 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 GAK66868.1 - 0.0027 18.1 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAK66868.1 - 0.0047 15.8 0.7 0.44 9.3 0.2 3.0 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.6 GAK66868.1 - 0.0056 16.7 4.4 2.4 8.1 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 GAK66868.1 - 0.01 16.1 0.0 4.7 7.5 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Tox-WTIP PF15654.6 GAK66868.1 - 0.14 12.6 0.5 4.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif SRPRB PF09439.10 GAK66869.1 - 3.4e-12 46.2 0.1 8e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 GAK66869.1 - 4.5e-07 29.5 0.0 6.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK66869.1 - 2.6e-05 24.2 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK66869.1 - 4.7e-05 23.0 0.2 0.0075 15.8 0.0 2.4 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 GAK66869.1 - 0.0027 17.9 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAK66869.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras family Proteasome PF00227.26 GAK66870.1 - 4.3e-46 156.8 0.0 5.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAK66870.1 - 6.4e-13 48.1 0.1 1.2e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF883 PF05957.13 GAK66871.1 - 5.3e-05 23.7 26.8 0.0029 18.2 1.6 3.4 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 GAK66871.1 - 0.0003 20.7 20.0 0.00055 19.9 20.0 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mitofilin PF09731.9 GAK66871.1 - 0.026 13.4 24.1 0.034 13.0 24.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ApoO PF09769.9 GAK66871.1 - 0.063 13.2 0.7 11 6.0 0.5 2.5 2 0 0 2 2 2 0 Apolipoprotein O ApoLp-III PF07464.11 GAK66871.1 - 0.15 12.1 20.8 0.054 13.6 16.0 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 GAK66871.1 - 0.33 11.5 36.2 1.8e+04 -11.5 36.2 3.9 1 1 0 1 1 1 0 YtxH-like protein Prominin PF05478.11 GAK66871.1 - 2.6 5.9 4.3 3.6 5.4 4.3 1.3 1 0 0 1 1 1 0 Prominin DBINO PF13892.6 GAK66871.1 - 8 6.8 25.7 1.8 8.9 14.3 2.2 1 1 1 2 2 2 0 DNA-binding domain SART-1 PF03343.13 GAK66872.1 - 4.1e-168 560.8 58.2 5.8e-168 560.3 58.2 1.2 1 0 0 1 1 1 1 SART-1 family PQ-loop PF04193.14 GAK66873.1 - 1.9e-32 110.8 0.4 3.2e-17 62.0 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat UPF0113_N PF17833.1 GAK66874.1 - 4.9e-30 103.9 0.0 7.6e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GAK66874.1 - 2e-24 85.7 0.0 3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 GAK66874.1 - 0.067 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Utp14 PF04615.13 GAK66875.1 - 3.7e-190 634.2 54.9 3.7e-190 634.2 54.9 2.2 1 1 1 2 2 2 1 Utp14 protein RhoGAP PF00620.27 GAK66876.1 - 1.2e-24 86.8 0.0 2.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M23 PF01551.22 GAK66877.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M23 Y_phosphatase PF00102.27 GAK66878.1 - 8.9e-39 133.4 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAK66878.1 - 0.0058 16.4 1.2 0.017 14.9 0.5 1.9 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain DSBA PF01323.20 GAK66879.1 - 1.1e-28 100.3 0.0 1.3e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain HpcH_HpaI PF03328.14 GAK66880.1 - 2.3e-41 141.3 0.3 3.2e-41 140.9 0.3 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 GAK66880.1 - 1.4e-10 40.9 0.3 0.00017 20.8 0.1 2.2 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Aminotran_1_2 PF00155.21 GAK66881.1 - 8.8e-48 163.3 0.0 1.4e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PIG-L PF02585.17 GAK66881.1 - 0.015 15.9 0.0 0.071 13.7 0.0 2.2 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase PQ-loop PF04193.14 GAK66882.1 - 4.5e-22 77.6 6.5 7.6e-15 54.4 0.0 3.2 2 1 1 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 GAK66882.1 - 0.0001 23.2 2.9 0.019 15.8 0.6 2.2 2 0 0 2 2 2 2 ER lumen protein retaining receptor DUF4834 PF16118.5 GAK66882.1 - 0.14 13.1 5.6 1.2 10.2 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Hid1 PF12722.7 GAK66882.1 - 1.2 7.1 5.2 0.3 9.2 1.6 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Endonuclease_NS PF01223.23 GAK66883.1 - 1.1e-54 185.6 0.0 9.2e-54 182.6 0.0 1.9 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease E1_dh PF00676.20 GAK66884.1 - 4.5e-89 298.3 0.1 5.5e-89 298.1 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAK66884.1 - 0.0073 15.5 0.0 0.02 14.1 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Aminotran_3 PF00202.21 GAK66886.1 - 1.4e-90 303.9 0.0 2.6e-90 303.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III GFO_IDH_MocA PF01408.22 GAK66887.1 - 6.4e-17 62.5 0.1 9.8e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAK66887.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 GAK66887.1 - 0.015 16.0 0.2 0.075 13.8 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Big_5 PF13205.6 GAK66887.1 - 0.098 13.4 0.7 0.24 12.1 0.6 1.7 2 0 0 2 2 2 0 Bacterial Ig-like domain Pex19 PF04614.12 GAK66888.1 - 5.5e-67 226.1 1.2 5.5e-67 226.1 1.2 1.6 2 0 0 2 2 2 1 Pex19 protein family T4SS PF07996.11 GAK66888.1 - 0.033 14.6 1.7 0.04 14.3 0.1 1.9 2 1 0 2 2 2 0 Type IV secretion system proteins RasGAP PF00616.19 GAK66889.1 - 8.1e-49 166.2 0.0 2.9e-48 164.3 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAK66889.1 - 9.4e-48 161.8 4.8 2.7e-47 160.4 4.8 1.9 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 GAK66889.1 - 6.5e-22 75.2 44.6 0.031 14.1 0.1 12.4 12 0 0 12 12 12 11 IQ calmodulin-binding motif CH PF00307.31 GAK66889.1 - 3.7e-16 59.3 0.0 1.4e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain SUIM_assoc PF16619.5 GAK66891.1 - 0.003 17.6 0.5 0.003 17.6 0.5 3.6 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Nipped-B_C PF12830.7 GAK66892.1 - 8.9e-47 159.5 0.5 3.6e-46 157.5 0.5 2.2 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GAK66892.1 - 0.00034 20.9 2.3 0.00034 20.9 2.3 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 GAK66892.1 - 0.00079 19.5 0.7 0.0047 17.0 0.4 2.5 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAK66892.1 - 0.0011 19.0 1.0 11 6.5 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat Peptidase_M24 PF00557.24 GAK66893.1 - 5.3e-19 68.7 0.4 1.1e-18 67.8 0.4 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 SH3_2 PF07653.17 GAK66893.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.22 GAK66894.1 - 7.3e-75 252.5 0.0 1.1e-58 199.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ost4 PF10215.9 GAK66894.1 - 1.6 8.6 3.8 1.5 8.7 1.2 2.2 2 0 0 2 2 2 0 Oligosaccaryltransferase Endosulfine PF04667.17 GAK66895.1 - 1.1e-24 86.3 0.1 2.1e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Porin_3 PF01459.22 GAK66896.1 - 2.3e-75 253.6 0.9 2.6e-75 253.3 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Hpt PF01627.23 GAK66897.1 - 2e-08 34.4 0.4 5.3e-08 33.0 0.1 1.8 1 1 1 2 2 2 1 Hpt domain Arrestin_C PF02752.22 GAK66898.1 - 3.4e-12 47.0 2.8 4.1e-11 43.5 2.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAK66898.1 - 1.5e-07 31.6 0.2 0.0021 18.1 0.3 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAK66898.1 - 0.15 11.7 0.1 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Arrestin_N terminal like DDHD PF02862.17 GAK66899.1 - 1.7e-37 129.8 0.0 1.7e-37 129.8 0.0 3.6 3 1 0 3 3 3 1 DDHD domain Cupin_8 PF13621.6 GAK66900.1 - 2.1e-22 80.0 0.0 4.4e-22 79.0 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAK66900.1 - 8e-09 35.4 0.0 4.4e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 GAK66900.1 - 0.011 16.2 0.0 0.081 13.4 0.0 2.3 1 1 0 1 1 1 0 JmjC domain, hydroxylase AraC_binding PF02311.19 GAK66900.1 - 0.039 13.8 0.0 0.71 9.8 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.11 GAK66900.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Cupin domain Tcp11 PF05794.13 GAK66902.1 - 1.6e-96 324.1 0.0 4e-96 322.8 0.0 1.7 1 0 0 1 1 1 1 T-complex protein 11 NIF PF03031.18 GAK66903.1 - 4.6e-55 185.7 0.1 6.6e-55 185.1 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Presenilin PF01080.17 GAK66903.1 - 8.5 5.0 6.3 15 4.2 6.3 1.4 1 0 0 1 1 1 0 Presenilin HLH PF00010.26 GAK66904.1 - 4.4e-18 65.0 1.6 9.4e-18 63.9 1.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 GAK66904.1 - 0.025 14.6 32.0 0.12 12.3 32.1 2.1 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIP3 PF03915.13 GAK66904.1 - 1.6 7.7 6.4 4.7 6.2 0.2 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 RIBIOP_C PF04950.12 GAK66905.1 - 1.2e-92 310.5 0.0 1.2e-92 310.5 0.0 1.8 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAK66905.1 - 2.7e-32 110.7 0.0 8.5e-32 109.1 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 GAK66905.1 - 1.2e-05 25.0 0.0 0.0012 18.4 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAK66905.1 - 2.4e-05 24.6 0.0 6.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK66905.1 - 0.00015 22.2 4.0 0.00024 21.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.9 GAK66905.1 - 0.00033 20.4 0.1 0.00094 18.9 0.1 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 GAK66905.1 - 0.0015 19.0 0.1 0.004 17.6 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAK66905.1 - 0.0033 17.8 0.0 0.0085 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 GAK66905.1 - 0.0055 16.9 1.0 0.02 15.1 0.0 2.5 2 1 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 GAK66905.1 - 0.0064 16.6 0.1 0.027 14.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 GAK66905.1 - 0.0076 16.2 0.5 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GAK66905.1 - 0.011 16.3 2.4 0.017 15.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 GAK66905.1 - 0.014 14.6 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 GAK66905.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 GAK66905.1 - 0.024 14.7 0.1 0.08 13.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAK66905.1 - 0.029 14.6 1.2 0.091 13.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAK66905.1 - 0.051 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 GAK66905.1 - 0.089 13.0 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 GAK66905.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 GAK66905.1 - 0.43 10.5 4.2 0.83 9.5 0.0 2.7 2 1 0 3 3 3 0 RsgA GTPase Zn_clus PF00172.18 GAK66906.1 - 0.00019 21.5 9.3 0.00034 20.7 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_capsid PF06112.11 GAK66906.1 - 0.016 15.2 0.4 0.016 15.2 0.4 2.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PEMT PF04191.13 GAK66908.1 - 1.3e-33 115.5 4.1 3e-33 114.4 4.1 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase Pkinase PF00069.25 GAK66909.1 - 2.3e-62 210.8 0.0 3.7e-61 206.8 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK66909.1 - 8.7e-34 117.0 0.0 1.5e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 GAK66909.1 - 4.1e-23 81.3 21.2 2.3e-12 46.8 8.8 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 GAK66909.1 - 6.4e-20 70.8 26.4 3.4e-11 42.9 9.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 GAK66909.1 - 3.2e-08 34.1 0.6 1.8e-07 31.7 0.6 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 GAK66909.1 - 2.1e-06 28.0 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 GAK66909.1 - 0.0044 16.4 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Uds1 PF15456.6 GAK66909.1 - 3.3 7.9 11.9 22 5.2 5.8 3.1 2 1 1 3 3 3 0 Up-regulated During Septation RhoGAP PF00620.27 GAK66910.1 - 5.5e-10 39.3 0.1 3e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 GAK66910.1 - 0.0025 18.0 0.1 0.0092 16.2 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RIO1 PF01163.22 GAK66911.1 - 7.1e-69 231.2 0.0 7.1e-69 231.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family BUD22 PF09073.10 GAK66911.1 - 0.013 14.9 38.7 0.0097 15.3 12.2 2.3 2 0 0 2 2 2 0 BUD22 Pkinase PF00069.25 GAK66911.1 - 0.043 13.2 0.1 0.085 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein kinase domain YL1 PF05764.13 GAK66911.1 - 0.65 10.1 37.5 0.034 14.3 17.2 2.8 2 1 0 2 2 2 0 YL1 nuclear protein SDA1 PF05285.12 GAK66911.1 - 1.3 8.4 37.4 0.1 12.0 16.7 2.3 2 0 0 2 2 2 0 SDA1 Hist_deacetyl PF00850.19 GAK66912.1 - 7.8e-44 150.4 0.8 1.5e-43 149.5 0.8 1.4 1 1 0 1 1 1 1 Histone deacetylase domain TRAP-gamma PF07074.12 GAK66912.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) PQ-loop PF04193.14 GAK66914.1 - 2.6e-33 113.6 5.8 1.5e-17 63.1 0.7 2.6 3 0 0 3 3 3 2 PQ loop repeat ZYG-11_interact PF05884.12 GAK66914.1 - 0.018 14.5 0.6 0.031 13.7 0.6 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3537 PF12056.8 GAK66914.1 - 0.08 11.7 0.2 0.14 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF202 PF02656.15 GAK66914.1 - 6.7 7.2 8.2 3.8 8.0 0.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF805 PF05656.14 GAK66914.1 - 7.3 7.1 7.7 14 6.1 5.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF805) TBP-binding PF09247.11 GAK66915.1 - 0.051 13.8 0.6 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 TATA box-binding protein binding PHY PF00360.20 GAK66916.1 - 8.8e-26 90.3 0.0 1.6e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 GAK66916.1 - 8.7e-22 77.8 0.1 2.3e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAK66916.1 - 1.4e-15 57.5 0.1 6.3e-15 55.3 0.1 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 GAK66916.1 - 5.2e-12 46.5 0.0 1.5e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 GAK66916.1 - 4.5e-11 42.6 1.5 1.2e-10 41.3 1.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 GAK66916.1 - 2.9e-09 37.5 0.0 7.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold Ras PF00071.22 GAK66918.1 - 1.4e-55 187.3 0.0 2.1e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK66918.1 - 8.9e-21 74.3 0.0 1.5e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK66918.1 - 1e-05 25.1 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAK66918.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Asp PF00026.23 GAK66919.1 - 5.4e-18 65.5 0.0 5e-11 42.6 0.3 2.5 2 0 0 2 2 2 2 Eukaryotic aspartyl protease DUF4381 PF14316.6 GAK66919.1 - 0.026 14.8 1.0 0.026 14.8 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PTP_tm PF18861.1 GAK66919.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J zf-C3HC4_3 PF13920.6 GAK66921.1 - 1.6e-08 34.3 16.3 3.1e-08 33.4 16.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MTABC_N PF16185.5 GAK66921.1 - 0.037 13.5 0.7 0.59 9.6 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region MIG-14_Wnt-bd PF06664.12 GAK66921.1 - 0.12 11.5 0.3 0.22 10.7 0.3 1.4 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Prok-RING_4 PF14447.6 GAK66921.1 - 6.6 6.7 14.1 15 5.6 14.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ADH_N PF08240.12 GAK66922.1 - 2e-31 108.1 0.2 3.6e-31 107.3 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK66922.1 - 7.2e-17 61.6 0.3 1.4e-16 60.7 0.3 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAK66922.1 - 0.0004 19.8 0.2 0.00058 19.2 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 GAK66922.1 - 0.0004 19.9 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 GAK66922.1 - 0.037 14.3 0.2 0.064 13.5 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N_assoc PF13823.6 GAK66922.1 - 0.057 13.4 0.3 0.057 13.4 0.3 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated ThiF PF00899.21 GAK66923.1 - 8.6e-39 133.3 0.0 1.8e-38 132.3 0.0 1.4 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 GAK66923.1 - 0.015 15.6 0.2 0.47 10.7 0.2 2.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 GAK66923.1 - 0.033 13.4 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ILVD_EDD PF00920.21 GAK66924.1 - 1e-200 667.8 0.6 1.2e-200 667.5 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family Mucin PF01456.17 GAK66925.1 - 0.12 12.3 18.3 0.17 11.8 18.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SOG2 PF10428.9 GAK66925.1 - 3.1 6.9 11.2 3.3 6.8 11.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM208_SND2 PF05620.11 GAK66926.1 - 2.5e-48 164.1 5.1 3.9e-48 163.4 5.1 1.3 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 HA2 PF04408.23 GAK66928.1 - 3.5e-21 75.5 0.0 3.5e-21 75.5 0.0 2.9 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAK66928.1 - 8.8e-19 67.7 0.0 2.3e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAK66928.1 - 8.5e-16 58.3 0.0 2.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK66928.1 - 1.9e-07 31.1 0.0 3.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK66928.1 - 3e-05 24.3 0.1 0.00036 20.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAK66928.1 - 9.4e-05 22.2 0.1 0.00032 20.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAK66928.1 - 0.00023 21.5 0.6 0.0038 17.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain T2SSE PF00437.20 GAK66928.1 - 0.0011 18.1 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 GAK66928.1 - 0.011 15.3 0.0 0.046 13.4 0.0 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAK66928.1 - 0.042 14.2 0.0 0.28 11.6 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain LYTB PF02401.18 GAK66928.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 LytB protein Atg14 PF10186.9 GAK66929.1 - 1.1e-22 80.5 9.7 2.5e-15 56.4 0.1 2.6 2 1 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 GAK66931.1 - 1e-21 76.8 25.2 0.0063 17.3 0.0 10.4 10 0 0 10 10 10 6 WD domain, G-beta repeat CTP_transf_like PF01467.26 GAK66931.1 - 2.6e-07 30.9 0.0 1.6e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like ANAPC4_WD40 PF12894.7 GAK66931.1 - 6.3e-06 26.4 2.3 5.7 7.3 0.0 6.6 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain ATE_C PF04377.15 GAK66932.1 - 2.4e-47 160.9 0.1 3.7e-47 160.3 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 GAK66932.1 - 1e-27 96.3 0.9 2.4e-27 95.1 0.9 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DSS1_SEM1 PF05160.13 GAK66933.1 - 3.9e-18 65.3 6.7 7.8e-18 64.3 6.7 1.5 1 1 0 1 1 1 1 DSS1/SEM1 family DUF3306 PF11748.8 GAK66933.1 - 1.5 9.7 6.0 2.2 9.2 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3306) SRA1 PF07304.11 GAK66934.1 - 1.4e-05 24.9 0.0 4.9e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 GAK66934.1 - 1.9e-05 25.3 6.0 1.4 9.9 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Prp18 PF02840.15 GAK66934.1 - 0.024 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain DUF1681 PF07933.14 GAK66935.1 - 5.9e-53 178.6 0.0 7e-53 178.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF3712 PF12505.8 GAK66936.1 - 5.2e-34 117.2 0.0 4e-23 82.0 0.0 4.9 5 0 0 5 5 5 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAK66936.1 - 3.4e-05 24.3 0.0 0.057 14.0 0.0 4.6 5 0 0 5 5 5 1 Late embryogenesis abundant protein ANAPC4 PF12896.7 GAK66937.1 - 8.8e-23 80.9 0.1 1.9e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ETF PF01012.21 GAK66938.1 - 1e-45 155.9 1.2 1.6e-45 155.2 1.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 GAK66938.1 - 3.7e-33 113.4 0.3 7.1e-33 112.5 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DHH PF01368.20 GAK66939.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 DHH family SIR2 PF02146.17 GAK66940.1 - 1.9e-26 93.1 0.0 7.7e-21 74.8 0.0 3.2 3 0 0 3 3 3 2 Sir2 family Replic_Relax PF13814.6 GAK66940.1 - 0.13 12.3 0.6 0.55 10.3 0.1 2.1 2 0 0 2 2 2 0 Replication-relaxation Rdx PF10262.9 GAK66941.1 - 8e-14 51.6 0.0 2.7e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Rdx family TMEM135_C_rich PF15982.5 GAK66943.1 - 0.005 17.4 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF2381 PF09544.10 GAK66943.1 - 8 5.9 8.7 0.29 10.6 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2381) IncD PF17628.2 GAK66944.1 - 0.39 10.5 2.9 0.41 10.4 0.7 2.2 2 0 0 2 2 2 0 Inclusion membrane protein D EB1 PF03271.17 GAK66945.1 - 4.3e-17 62.1 0.7 7.4e-17 61.3 0.7 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GAK66945.1 - 0.0001 22.4 0.1 0.00023 21.3 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 GAK66945.1 - 0.02 15.0 0.1 0.036 14.2 0.1 1.5 1 0 0 1 1 1 0 CH-like domain in sperm protein DUF3138 PF11336.8 GAK66945.1 - 2 6.9 4.4 1.5 7.4 2.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Homeodomain PF00046.29 GAK66946.1 - 7.2e-12 45.0 1.9 1.5e-11 44.0 1.9 1.5 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 GAK66946.1 - 0.004 17.0 0.1 0.0083 16.0 0.1 1.4 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT BrkDBD PF09607.10 GAK66946.1 - 0.41 10.5 2.1 1 9.2 0.7 2.1 2 0 0 2 2 2 0 Brinker DNA-binding domain SLAC1 PF03595.17 GAK66947.1 - 3.3e-47 161.3 40.8 1.6e-32 113.0 18.1 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel DUF1974 PF09317.11 GAK66947.1 - 0.044 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Mito_carr PF00153.27 GAK66948.1 - 1.6e-31 108.1 4.8 2.4e-15 56.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_8 PF13450.6 GAK66949.1 - 8.1e-11 42.0 0.0 1.1e-08 35.2 0.0 2.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAK66949.1 - 0.09 12.8 0.0 0.09 12.8 0.0 2.9 4 1 0 4 4 4 0 FAD-NAD(P)-binding HA2 PF04408.23 GAK66950.1 - 2.8e-16 59.7 0.4 9.3e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAK66950.1 - 5.4e-15 55.7 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 GAK66950.1 - 5.6e-08 33.4 0.5 0.0048 17.6 0.0 3.1 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 GAK66950.1 - 6.7e-07 29.2 0.3 1.4e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 GAK66950.1 - 0.002 18.5 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 GAK66950.1 - 0.0026 18.1 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain GRP PF07172.11 GAK66950.1 - 1.5 9.6 56.4 7.2 7.4 2.6 3.8 3 0 0 3 3 3 0 Glycine rich protein family Fungal_trans PF04082.18 GAK66951.1 - 9.2e-09 34.7 0.8 1.7e-08 33.8 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK66951.1 - 0.0018 18.4 10.2 0.003 17.7 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribophorin_I PF04597.14 GAK66952.1 - 5.7e-119 398.2 0.0 6.5e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I CDC45 PF02724.14 GAK66953.1 - 4.9e-226 752.0 0.0 5.6e-226 751.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 GAK66953.1 - 0.12 12.4 6.4 0.19 11.8 6.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Apt1 PF10351.9 GAK66953.1 - 0.38 9.6 3.2 0.53 9.1 3.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt5_N PF11942.8 GAK66953.1 - 0.66 11.0 7.7 1.8 9.6 7.7 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal RasGEF PF00617.19 GAK66954.1 - 3.4e-42 144.6 0.0 5.6e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAK66954.1 - 3.7e-06 27.1 0.3 1.4e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Arf PF00025.21 GAK66954.1 - 0.055 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family GATA PF00320.27 GAK66955.1 - 2.5e-16 59.0 3.0 4.5e-16 58.2 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 GAK66955.1 - 0.12 12.5 0.3 0.29 11.3 0.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Nudix_N_2 PF14803.6 GAK66955.1 - 0.73 9.8 3.2 2.2 8.2 3.2 1.8 1 0 0 1 1 1 0 Nudix N-terminal p450 PF00067.22 GAK66956.1 - 5e-66 223.3 0.0 6.9e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NLRC4_HD PF17889.1 GAK66956.1 - 0.19 12.0 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 NLRC4 helical domain Fungal_trans PF04082.18 GAK66957.1 - 3.5e-08 32.8 0.1 5.7e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK66957.1 - 3.9e-08 33.3 9.7 7.1e-08 32.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 GAK66958.1 - 7.7e-16 58.4 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAK66958.1 - 3.2e-12 46.7 0.0 7.8e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAK66958.1 - 4.4e-12 46.0 0.0 7.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAK66958.1 - 1.7e-06 28.7 0.0 2.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAK66958.1 - 0.0001 22.5 0.0 0.00028 21.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAK66958.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAK66958.1 - 0.00024 21.2 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAK66958.1 - 0.032 14.3 0.1 0.15 12.1 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAK66958.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arrestin_C PF02752.22 GAK66959.1 - 4.5e-13 49.8 0.4 1.9e-10 41.3 0.4 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAK66959.1 - 0.0085 16.2 0.1 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Nuc_sug_transp PF04142.15 GAK66961.1 - 2.3e-50 171.6 7.9 7.1e-45 153.5 6.5 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 GAK66961.1 - 0.023 14.8 0.9 0.023 14.8 0.9 2.9 3 0 0 3 3 3 0 EamA-like transporter family Acyl_transf_3 PF01757.22 GAK66962.1 - 1.2e-12 47.6 32.2 1.6e-12 47.1 32.2 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF1772 PF08592.11 GAK66962.1 - 0.74 10.1 8.1 4.5 7.6 0.0 3.8 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Glyco_transf_90 PF05686.12 GAK66963.1 - 8.3e-19 67.8 0.8 1.1e-15 57.5 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 RcnB PF11776.8 GAK66963.1 - 0.027 14.5 0.7 0.078 13.1 0.7 1.7 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator Glyco_transf_90 PF05686.12 GAK66964.1 - 1.8e-08 33.7 0.1 6.2e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L22 PF00237.19 GAK66967.1 - 1.8e-23 82.7 0.2 4.1e-23 81.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e WLM PF08325.10 GAK66968.1 - 0.075 13.1 1.0 0.11 12.5 1.0 1.2 1 0 0 1 1 1 0 WLM domain SVIP PF15811.5 GAK66968.1 - 0.1 13.1 8.1 0.12 12.9 6.0 1.9 2 0 0 2 2 2 0 Small VCP/p97-interacting protein SelK_SelG PF10961.8 GAK66968.1 - 3.6 8.3 6.1 1.1 9.9 2.3 1.9 2 0 0 2 2 2 0 Selenoprotein SelK_SelG zf-CHCC PF10276.9 GAK66969.1 - 4.1e-18 65.2 2.0 6e-18 64.6 2.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain Aminotran_5 PF00266.19 GAK66970.1 - 9e-87 291.4 0.0 2e-86 290.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V ThrE PF06738.12 GAK66971.1 - 5.6e-60 202.7 4.5 5.6e-60 202.7 4.5 2.4 2 1 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 GAK66971.1 - 2.2e-07 31.1 3.3 2.2e-07 31.1 3.3 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE UPF0016 PF01169.19 GAK66971.1 - 0.045 14.1 0.3 0.045 14.1 0.3 3.1 4 0 0 4 4 4 0 Uncharacterized protein family UPF0016 HNH_3 PF13392.6 GAK66972.1 - 0.0019 17.9 0.3 0.0037 17.0 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF11 PF01345.18 GAK66972.1 - 0.062 13.6 0.3 0.23 11.8 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF11 Peptidase_M43 PF05572.13 GAK66973.1 - 1.1e-12 48.2 0.1 1.7e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAK66973.1 - 1.3e-07 31.9 1.5 1.8e-07 31.5 1.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAK66973.1 - 1.4e-06 28.8 0.1 2.4e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAK66973.1 - 0.0057 16.3 0.2 0.018 14.7 0.2 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAK66973.1 - 0.019 13.9 0.3 0.038 12.9 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 GAK66973.1 - 0.054 13.3 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin GDP_Man_Dehyd PF16363.5 GAK66974.1 - 0.16 11.3 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HNH_3 PF13392.6 GAK66975.1 - 1.7e-09 37.3 0.3 3.6e-09 36.2 0.3 1.6 1 0 0 1 1 1 1 HNH endonuclease PyrI PF01948.18 GAK66975.1 - 0.026 14.8 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain HNH_3 PF13392.6 GAK66976.1 - 1.7e-15 56.5 5.4 1.2e-08 34.6 0.2 2.4 2 0 0 2 2 2 2 HNH endonuclease PyrI PF01948.18 GAK66976.1 - 0.0047 17.1 0.0 0.034 14.4 0.0 2.1 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain AP2 PF00847.20 GAK66976.1 - 0.13 12.5 0.4 0.76 10.1 0.2 2.4 2 0 0 2 2 2 0 AP2 domain Mito_fiss_reg PF05308.11 GAK66976.1 - 2.5 8.1 6.7 0.61 10.1 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Peptidase_S15 PF02129.18 GAK66977.1 - 1.3e-40 139.7 0.1 1.6e-38 132.9 0.1 2.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAK66977.1 - 2e-32 113.0 0.0 3.3e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Epimerase PF01370.21 GAK66977.1 - 9e-25 87.5 0.0 2.6e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAK66977.1 - 2.1e-21 76.7 0.1 6.7e-20 71.7 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAK66977.1 - 6.7e-13 48.3 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAK66977.1 - 2.3e-09 36.8 0.0 3.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAK66977.1 - 1.5e-08 34.3 0.1 2.5e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAK66977.1 - 2.2e-07 30.3 0.0 3.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 GAK66977.1 - 5.1e-07 29.8 0.1 1e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAK66977.1 - 7e-07 29.3 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 GAK66977.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 GAK66977.1 - 0.001 18.3 0.0 0.0065 15.7 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein Hydrolase_4 PF12146.8 GAK66977.1 - 0.0053 16.1 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAK66977.1 - 0.12 11.9 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1479 PF07350.12 GAK66978.1 - 1e-07 31.1 0.1 0.0029 16.5 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 GAK66978.1 - 2.3e-07 31.3 0.0 1.2e-06 29.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 GAK66980.1 - 2.4e-49 168.2 44.6 2.3e-48 164.9 46.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAK66980.1 - 1.6e-20 73.1 19.6 2.8e-20 72.3 19.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAK66980.1 - 3.3e-12 46.0 10.4 3.3e-12 46.0 10.4 3.3 4 0 0 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.6 GAK66980.1 - 0.00034 19.3 9.0 0.00034 19.3 9.0 3.5 1 1 2 3 3 3 1 MFS/sugar transport protein CrgA PF06781.12 GAK66980.1 - 0.076 13.1 0.1 0.076 13.1 0.1 3.8 4 1 0 4 4 4 0 Cell division protein CrgA MFS_1 PF07690.16 GAK66981.1 - 3.1e-21 75.7 22.7 3.1e-21 75.7 22.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK66981.1 - 2.7e-13 49.6 3.4 2.7e-13 49.6 3.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3112 PF11309.8 GAK66981.1 - 1.9 7.9 6.3 18 4.7 4.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) Fungal_trans PF04082.18 GAK66982.1 - 1.2e-17 63.8 0.0 2.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK66982.1 - 1.2e-09 38.1 11.4 2e-09 37.4 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_127 PF07944.12 GAK66983.1 - 7.7e-30 103.9 0.0 9e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Beta-lactamase PF00144.24 GAK66984.1 - 3.4e-34 118.6 0.0 6.2e-34 117.7 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Amino_oxidase PF01593.24 GAK66985.1 - 1e-35 123.9 1.1 2.1e-23 83.3 0.1 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK66985.1 - 1.6e-15 57.1 0.0 7e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK66985.1 - 5e-06 26.3 2.5 0.00092 18.9 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK66985.1 - 0.00041 20.4 0.7 0.0041 17.1 0.1 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAK66985.1 - 0.0046 16.2 0.0 0.037 13.2 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAK66985.1 - 0.011 14.8 0.3 0.019 14.0 0.1 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAK66985.1 - 0.05 12.7 0.1 0.076 12.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAK66985.1 - 0.056 14.0 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAK66985.1 - 0.058 12.6 0.7 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 GAK66985.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Fzo_mitofusin PF04799.13 GAK66986.1 - 0.88 9.1 9.8 0.7 9.4 6.8 2.3 2 0 0 2 2 2 0 fzo-like conserved region LemA PF04011.12 GAK66986.1 - 5.1 6.9 7.2 17 5.3 7.2 1.8 1 0 0 1 1 1 0 LemA family Seryl_tRNA_N PF02403.22 GAK66986.1 - 7.8 6.8 22.2 0.37 11.0 8.4 3.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Snf7 PF03357.21 GAK66987.1 - 1.7e-14 53.8 8.2 2e-14 53.5 8.2 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 GAK66987.1 - 0.001 19.0 2.5 0.0016 18.4 2.5 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 GAK66987.1 - 0.031 13.9 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase FAM117 PF15388.6 GAK66987.1 - 0.13 11.7 0.5 0.17 11.2 0.5 1.1 1 0 0 1 1 1 0 Protein Family FAM117 zf-U1 PF06220.12 GAK66988.1 - 3.1e-19 68.4 4.2 4.3e-19 68.0 4.2 1.2 1 0 0 1 1 1 1 U1 zinc finger SPOB_a PF14689.6 GAK66988.1 - 0.19 11.4 0.3 0.27 11.0 0.3 1.1 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain PG_binding_4 PF12229.8 GAK66988.1 - 0.2 11.9 0.0 0.28 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative peptidoglycan binding domain WD40 PF00400.32 GAK66989.1 - 3.6e-07 30.8 0.1 0.15 12.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAK66989.1 - 0.0096 14.9 0.0 0.77 8.7 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GAK66989.1 - 0.22 11.8 0.0 15 6.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Aldedh PF00171.22 GAK66990.1 - 4.9e-160 533.0 3.0 5.6e-160 532.8 3.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAK66990.1 - 0.035 13.6 0.0 0.15 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) EVC2_like PF12297.8 GAK66990.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Tam41_Mmp37 PF09139.11 GAK66992.1 - 1e-112 376.7 0.0 1.2e-112 376.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial SOCS PF12610.8 GAK66992.1 - 0.17 12.3 1.2 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Suppressor of cytokine signalling Sugar_tr PF00083.24 GAK66993.1 - 5e-06 25.7 0.0 6.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter CDC45 PF02724.14 GAK66993.1 - 0.061 11.6 0.9 0.073 11.4 0.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAK66993.1 - 0.47 8.6 6.6 0.53 8.4 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GAK66993.1 - 0.48 9.7 9.3 0.86 8.9 9.3 1.4 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 GAK66993.1 - 1.4 8.2 7.6 2.1 7.7 7.6 1.3 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GAK66993.1 - 3.2 7.4 15.3 5.4 6.7 15.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 GAK66993.1 - 7.5 4.5 15.8 10 4.0 15.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sugar_tr PF00083.24 GAK66994.1 - 6.8e-102 341.6 23.0 8e-102 341.4 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK66994.1 - 3.2e-20 72.4 27.2 1.7e-19 70.0 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SGL PF08450.12 GAK66995.1 - 1.7e-16 60.6 0.1 4.3e-15 56.0 0.1 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF3404 PF11884.8 GAK66995.1 - 0.086 12.0 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) DUF3122 PF11320.8 GAK66996.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3122) 3-HAO PF06052.12 GAK66998.1 - 1.1e-57 193.9 0.0 1.4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 GAK66998.1 - 6.9e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAK66998.1 - 0.0015 18.2 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 GAK66998.1 - 0.007 16.6 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.19 GAK66998.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Zn_clus PF00172.18 GAK66999.1 - 0.00079 19.5 9.1 0.0015 18.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 GAK67000.1 - 3.5e-147 490.6 0.0 4.1e-147 490.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAK67000.1 - 3.5e-05 23.4 0.1 9.9e-05 21.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Iso_dh PF00180.20 GAK67001.1 - 1.3e-94 317.2 0.0 1.5e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHCH PF06747.13 GAK67002.1 - 7.6e-06 25.9 5.8 7.6e-06 25.9 5.8 2.4 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 GAK67002.1 - 7.5e-05 22.7 10.9 0.011 15.8 5.5 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF5558 PF17713.1 GAK67002.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5558) Pet191_N PF10203.9 GAK67002.1 - 0.2 12.0 11.5 11 6.3 0.2 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 GAK67002.1 - 1.8 8.6 13.6 1.3 9.1 2.4 3.0 1 1 3 4 4 4 0 Cytochrome c oxidase biogenesis protein Cmc1 like PPR_2 PF13041.6 GAK67003.1 - 2.3e-13 50.1 0.0 7.5e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 GAK67003.1 - 2e-07 30.8 0.5 1.5e-05 24.9 0.0 3.5 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 GAK67003.1 - 2.9e-06 27.3 0.0 7.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAK67003.1 - 1.5e-05 24.6 1.0 0.0093 15.7 0.2 2.7 2 0 0 2 2 2 2 PPR repeat PPR_long PF17177.4 GAK67003.1 - 0.0069 15.8 0.0 0.019 14.3 0.0 1.8 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Dioxygenase_C PF00775.21 GAK67004.1 - 4.8e-42 143.5 0.0 6.3e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAK67004.1 - 2.7e-27 94.4 0.0 4.9e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 GAK67004.1 - 2.1e-07 31.1 0.0 1e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 GAK67004.1 - 0.024 14.6 0.1 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Sep15_SelM PF08806.11 GAK67005.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain Mito_carr PF00153.27 GAK67006.1 - 9.6e-63 208.1 4.6 5.7e-20 71.0 0.3 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Zn_Tnp_IS1 PF03811.13 GAK67008.1 - 0.23 11.2 3.1 0.35 10.6 1.4 2.1 2 0 0 2 2 2 0 InsA N-terminal domain AAA_5 PF07728.14 GAK67010.1 - 1.6e-60 203.1 0.0 2.6e-26 92.2 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) MTA_R1 PF17226.2 GAK67010.1 - 0.099 12.8 0.1 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 MTA R1 domain DUF1967 PF09269.11 GAK67010.1 - 0.18 11.8 0.1 0.47 10.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) MCM PF00493.23 GAK67010.1 - 0.19 10.8 0.0 0.44 9.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain SRI PF08236.11 GAK67010.1 - 0.4 10.9 1.1 0.85 9.8 1.1 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Response_reg PF00072.24 GAK67013.1 - 3e-23 82.1 0.6 8.3e-16 58.1 0.3 2.4 1 1 1 2 2 2 2 Response regulator receiver domain DUF202 PF02656.15 GAK67014.1 - 2.7e-13 50.1 4.9 2.7e-13 50.1 4.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX2_TM PF02790.15 GAK67014.1 - 0.016 15.3 0.6 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF3429 PF11911.8 GAK67016.1 - 1.3e-40 139.0 13.7 2.1e-40 138.3 13.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DDHD PF02862.17 GAK67016.1 - 0.37 10.9 3.3 14 5.7 2.4 2.1 2 0 0 2 2 2 0 DDHD domain Paf1 PF03985.13 GAK67016.1 - 2 7.3 14.3 2.7 6.9 14.3 1.2 1 0 0 1 1 1 0 Paf1 COX14 PF14880.6 GAK67017.1 - 0.0021 17.9 0.1 0.0032 17.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly RRM_1 PF00076.22 GAK67018.1 - 5.6e-13 48.5 0.0 3.5e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAK67018.1 - 0.03 14.2 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif UDPGP PF01704.18 GAK67019.1 - 2.2e-200 665.6 0.1 2.5e-200 665.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase F_actin_cap_B PF01115.17 GAK67020.1 - 1e-87 293.8 0.0 1.5e-87 293.2 0.0 1.3 1 0 0 1 1 1 1 F-actin capping protein, beta subunit LapA_dom PF06305.11 GAK67020.1 - 0.4 10.5 0.9 0.57 10.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Cys_Met_Meta_PP PF01053.20 GAK67021.1 - 6.1e-148 492.4 0.0 6.9e-148 492.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAK67021.1 - 6e-11 41.9 0.7 1.1e-10 41.0 0.7 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAK67021.1 - 4.1e-09 36.2 0.2 6.1e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 GAK67021.1 - 5e-08 32.5 0.1 7.7e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAK67021.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 GAK67021.1 - 0.00094 17.8 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GAK67021.1 - 0.12 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein AP_endonuc_2 PF01261.24 GAK67021.1 - 0.13 11.7 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel SepSecS PF05889.13 GAK67021.1 - 0.2 10.3 0.1 0.28 9.8 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Arf PF00025.21 GAK67022.1 - 2.7e-77 258.2 0.0 3.1e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAK67022.1 - 3e-15 56.5 0.0 3.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAK67022.1 - 1.3e-12 47.6 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAK67022.1 - 2.2e-11 43.5 0.8 7.5e-07 28.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAK67022.1 - 1.1e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAK67022.1 - 3.7e-09 36.3 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAK67022.1 - 0.00022 21.3 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAK67022.1 - 0.0016 17.8 0.1 0.0024 17.2 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase SPRY PF00622.28 GAK67023.1 - 7.1e-22 77.8 0.1 1.2e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 SPRY domain bZIP_1 PF00170.21 GAK67024.1 - 7.9e-06 25.9 6.5 1.8e-05 24.7 6.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAK67024.1 - 0.097 12.8 5.7 1.2 9.3 6.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper RskA PF10099.9 GAK67024.1 - 3.8 7.8 41.8 1e+02 3.1 22.3 3.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA zf-HC5HC2H_2 PF13832.6 GAK67025.1 - 5e-20 71.7 2.5 5e-20 71.7 2.5 4.1 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAK67025.1 - 2.5e-15 56.5 3.7 2.5e-15 56.5 3.7 4.5 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 GAK67025.1 - 1.5e-13 50.4 24.4 1e-09 38.1 6.4 5.7 7 0 0 7 7 7 3 PHD-finger BAH PF01426.18 GAK67025.1 - 3.1e-08 33.5 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.6 GAK67025.1 - 1.4e-07 30.9 4.4 1.4e-07 30.9 4.4 5.0 7 0 0 7 7 7 2 PHD-finger GATA PF00320.27 GAK67025.1 - 3.2e-06 26.6 1.7 3.2e-06 26.6 1.7 3.5 3 0 0 3 3 3 1 GATA zinc finger ELM2 PF01448.24 GAK67025.1 - 0.00036 21.2 0.0 0.0021 18.8 0.0 2.4 2 1 0 2 2 2 1 ELM2 domain DUF2415 PF10313.9 GAK67026.1 - 8.9e-06 25.5 0.0 2.8e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 GAK67026.1 - 1.1e-05 25.6 0.0 0.045 14.1 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAK67026.1 - 0.00011 22.1 0.4 0.43 10.6 0.4 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 GAK67026.1 - 0.0014 19.4 6.2 0.13 13.2 1.9 5.1 3 1 1 4 4 4 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAK67026.1 - 0.021 13.8 0.1 0.058 12.3 0.1 1.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAK67026.1 - 0.04 13.2 0.1 0.094 12.0 0.1 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.21 GAK67026.1 - 0.07 11.9 0.1 1.4 7.6 0.0 2.6 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 GAK67026.1 - 6.8 6.5 7.0 20 5.0 0.8 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Cyclin PF08613.11 GAK67027.1 - 1.5e-11 45.0 0.7 2.9e-11 44.0 0.0 1.9 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAK67027.1 - 1.1e-06 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA PF00004.29 GAK67031.1 - 2.2e-32 112.3 0.0 3.7e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAK67031.1 - 2.4e-07 31.1 0.3 1.4e-06 28.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK67031.1 - 9.5e-07 29.3 0.0 2.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GAK67031.1 - 4.9e-05 23.5 0.1 0.00015 21.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAK67031.1 - 7.1e-05 23.4 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAK67031.1 - 0.00014 22.0 0.0 0.00034 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 GAK67031.1 - 0.00033 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAK67031.1 - 0.00063 19.7 0.9 0.004 17.1 0.3 2.4 2 1 0 2 2 1 1 NACHT domain ATPase_2 PF01637.18 GAK67031.1 - 0.00071 19.6 0.4 0.2 11.6 0.4 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 GAK67031.1 - 0.00074 19.3 0.0 0.003 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAK67031.1 - 0.00079 18.7 0.0 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAK67031.1 - 0.0016 18.7 0.1 0.0067 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAK67031.1 - 0.0018 18.6 0.0 0.005 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 GAK67031.1 - 0.002 17.9 0.1 0.0056 16.4 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAK67031.1 - 0.0024 17.6 0.0 0.0066 16.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 GAK67031.1 - 0.0025 17.6 0.1 0.0072 16.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 GAK67031.1 - 0.0026 17.8 0.4 0.0087 16.1 0.4 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 GAK67031.1 - 0.0027 17.5 0.2 0.0069 16.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 GAK67031.1 - 0.0035 17.3 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 GAK67031.1 - 0.0039 16.8 4.7 0.21 11.2 1.8 3.1 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 GAK67031.1 - 0.0045 16.7 0.1 0.012 15.4 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase Viral_helicase1 PF01443.18 GAK67031.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 GAK67031.1 - 0.0098 15.4 0.1 0.035 13.6 0.0 1.9 3 0 0 3 3 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 GAK67031.1 - 0.013 16.0 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 GAK67031.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 GAK67031.1 - 0.019 15.4 0.0 0.049 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAK67031.1 - 0.026 14.5 0.1 0.068 13.1 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 GAK67031.1 - 0.031 14.6 0.6 0.18 12.1 0.0 2.5 3 1 1 4 4 2 0 AAA domain KAP_NTPase PF07693.14 GAK67031.1 - 0.031 13.5 0.2 7.8 5.6 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.9 GAK67031.1 - 0.039 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 GAK67031.1 - 0.041 13.3 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 GAK67031.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 GAK67031.1 - 0.082 12.2 0.3 1.1 8.6 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.11 GAK67031.1 - 0.14 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 GAK67031.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 GAK67031.1 - 0.15 11.5 0.1 0.41 10.1 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_13 PF13166.6 GAK67031.1 - 0.17 10.5 0.0 0.44 9.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 GAK67032.1 - 1.9e-18 67.0 0.0 5e-17 62.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK67032.1 - 4.8e-16 58.8 0.0 8.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK67032.1 - 1.7e-15 58.2 0.2 2.5e-15 57.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAK67032.1 - 6.9e-06 25.8 0.1 0.03 13.9 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAK67032.1 - 1.3e-05 24.8 0.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 GAK67032.1 - 0.00029 21.0 0.1 0.0022 18.1 0.1 2.1 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 GAK67032.1 - 0.0018 17.9 0.0 0.0051 16.5 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.13 GAK67032.1 - 0.0055 16.6 0.1 0.055 13.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 GAK67032.1 - 0.048 13.2 0.1 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase LEA_5 PF00477.17 GAK67032.1 - 0.17 12.4 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 Small hydrophilic plant seed protein TRIC PF05197.13 GAK67033.1 - 0.039 13.5 0.8 0.17 11.4 0.8 1.9 1 1 0 1 1 1 0 TRIC channel DNA_binding_1 PF01035.20 GAK67034.1 - 1.9e-22 79.2 0.0 2.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SPT16 PF08644.11 GAK67035.1 - 9.2e-56 188.2 0.0 2.4e-55 186.9 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 GAK67035.1 - 7.2e-51 172.2 0.2 1.7e-50 171.0 0.2 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 GAK67035.1 - 3.7e-29 101.9 0.0 7.9e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GAK67035.1 - 4.6e-15 55.8 0.5 1.4e-14 54.3 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Atg8 PF02991.16 GAK67036.1 - 1.1e-49 166.9 0.1 2.1e-49 166.0 0.1 1.5 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like HEAT PF02985.22 GAK67036.1 - 3.3e-10 39.3 16.9 0.51 10.7 0.0 10.0 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 GAK67036.1 - 9.9e-09 35.5 9.2 6.9e-05 23.2 0.1 4.8 4 1 0 4 4 4 3 HEAT repeats Cnd1 PF12717.7 GAK67036.1 - 3.5e-07 30.4 0.4 0.011 15.8 0.0 3.5 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 APG12 PF04110.13 GAK67036.1 - 7.9e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Adaptin_N PF01602.20 GAK67036.1 - 0.0055 15.3 0.5 0.068 11.7 0.1 2.5 3 0 0 3 3 3 1 Adaptin N terminal region OPT PF03169.15 GAK67037.1 - 7.7e-178 592.9 50.7 9.1e-178 592.7 50.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AChE_tetra PF08674.10 GAK67038.1 - 0.047 13.4 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain PDEase_II PF02112.15 GAK67039.1 - 1.9e-36 125.9 0.0 7.3e-22 77.9 0.0 3.2 3 1 0 3 3 3 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 GAK67039.1 - 0.005 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3693 PF12472.8 GAK67039.1 - 0.16 11.7 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 Phage related protein DUF913 PF06025.12 GAK67040.1 - 3.4e-99 332.3 0.0 3.4e-99 332.3 0.0 6.0 6 1 0 6 6 6 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 GAK67040.1 - 1.2e-89 301.3 1.4 1.2e-89 301.3 1.4 5.5 6 1 1 7 7 7 1 Domain of Unknown Function (DUF908) UBM PF14377.6 GAK67040.1 - 3.8e-19 67.5 12.0 2.3e-11 42.7 0.9 4.0 3 0 0 3 3 3 2 Ubiquitin binding region UBA PF00627.31 GAK67040.1 - 3e-11 43.0 0.1 9.2e-11 41.4 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Atg14 PF10186.9 GAK67040.1 - 0.53 9.3 5.3 1.3 8.0 5.3 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PEP-utilisers_N PF05524.13 GAK67040.1 - 0.88 9.8 12.6 1.9 8.7 5.9 3.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Spc7 PF08317.11 GAK67040.1 - 1.1 8.1 8.0 2.2 7.1 8.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein GBP_C PF02841.14 GAK67040.1 - 9.4 5.5 11.1 24 4.2 11.1 1.6 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Cullin PF00888.22 GAK67041.1 - 9.2e-168 559.7 0.0 1.3e-167 559.2 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAK67041.1 - 1.6e-21 76.1 2.4 4.4e-21 74.7 2.4 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain AAA_28 PF13521.6 GAK67041.1 - 1.1 9.4 4.7 4.4 7.5 0.1 3.4 2 1 0 3 3 3 0 AAA domain Ferritin_2 PF13668.6 GAK67042.1 - 2.2e-41 141.3 1.6 3.6e-41 140.5 1.6 1.3 1 0 0 1 1 1 1 Ferritin-like domain L-fibroin PF05849.11 GAK67042.1 - 0.0019 17.6 0.2 0.0042 16.4 0.2 1.6 1 0 0 1 1 1 1 Fibroin light chain (L-fibroin) MAPEG PF01124.18 GAK67043.1 - 2.3e-20 72.8 3.9 3.3e-20 72.3 3.9 1.2 1 0 0 1 1 1 1 MAPEG family eIF-5_eIF-2B PF01873.17 GAK67045.1 - 8.1e-39 132.1 0.0 1.3e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 GAK67045.1 - 1.2e-19 70.2 0.0 1.2e-19 70.2 0.0 2.9 4 0 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Sigma70_ner PF04546.13 GAK67045.1 - 0.0034 17.3 0.0 6.7 6.5 0.0 2.6 2 1 0 2 2 2 1 Sigma-70, non-essential region DNA_RNApol_7kD PF03604.13 GAK67045.1 - 0.2 11.3 2.1 0.57 9.9 2.1 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Cwf_Cwc_15 PF04889.12 GAK67045.1 - 0.32 10.7 19.1 1.7 8.3 10.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lon_C PF05362.13 GAK67046.1 - 1.9e-68 230.0 0.0 3e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 GAK67046.1 - 7.9e-23 81.3 0.0 1.7e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 GAK67046.1 - 1.4e-11 44.7 0.0 1.2e-10 41.7 0.0 2.1 1 1 1 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 GAK67046.1 - 5.6e-10 39.4 0.0 1.5e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 GAK67046.1 - 9.7e-08 31.9 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 GAK67046.1 - 7.2e-05 23.0 0.0 0.00045 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAK67046.1 - 0.00022 21.7 0.1 0.00022 21.7 0.1 2.9 3 1 0 3 3 1 1 AAA ATPase domain AAA_22 PF13401.6 GAK67046.1 - 0.00047 20.5 0.2 0.0092 16.3 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 GAK67046.1 - 0.0012 19.0 0.3 0.0086 16.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 GAK67046.1 - 0.0086 16.6 1.5 0.039 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAK67046.1 - 0.0089 15.4 0.1 0.027 13.9 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAK67046.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAK67046.1 - 0.016 14.9 0.0 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAK67046.1 - 0.029 14.8 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 GAK67046.1 - 0.033 13.8 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAK67046.1 - 0.045 13.5 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAK67046.1 - 0.046 13.2 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 GAK67046.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_PrkA PF08298.11 GAK67046.1 - 0.059 12.3 0.0 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain IstB_IS21 PF01695.17 GAK67046.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 GAK67046.1 - 0.073 12.4 0.0 25 4.1 0.0 3.2 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 GAK67046.1 - 0.093 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAK67046.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain SinI PF08671.10 GAK67046.1 - 0.1 12.4 0.2 0.26 11.1 0.2 1.7 1 0 0 1 1 1 0 Anti-repressor SinI KTI12 PF08433.10 GAK67046.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 GAK67046.1 - 0.15 11.9 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GAK67046.1 - 0.21 11.8 2.1 0.61 10.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 GAK67046.1 - 0.4 10.4 3.7 0.25 11.1 0.1 2.1 1 1 1 2 2 2 0 AAA domain Bromodomain PF00439.25 GAK67047.1 - 5.1e-18 64.9 0.0 1.5e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Bromodomain BAH PF01426.18 GAK67047.1 - 1e-11 44.7 0.1 1.7e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 BAH domain LSM14 PF12701.7 GAK67048.1 - 3.8e-29 100.6 0.0 5.6e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GAK67048.1 - 7.7e-08 33.2 0.5 0.0094 16.8 0.3 2.7 2 0 0 2 2 2 2 FDF domain SM-ATX PF14438.6 GAK67048.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LPP PF04728.13 GAK67049.1 - 0.015 15.7 2.2 0.04 14.3 2.2 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Gly-zipper_Omp PF13488.6 GAK67049.1 - 8.7 6.4 18.7 3.5 7.7 0.9 2.6 2 1 0 2 2 2 0 Glycine zipper Mannosyl_trans2 PF04188.13 GAK67050.1 - 2.3e-47 162.3 12.9 2.8e-47 162.0 12.9 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Arf PF00025.21 GAK67051.1 - 1.2e-62 210.4 0.0 1.9e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAK67051.1 - 4.7e-12 46.2 0.1 1.3e-11 44.7 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAK67051.1 - 2.6e-11 43.3 0.0 4.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Methyltransf_23 PF13489.6 GAK67051.1 - 4.2e-11 42.9 0.0 8.9e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ras PF00071.22 GAK67051.1 - 1.3e-10 41.1 0.0 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Methyltransf_12 PF08242.12 GAK67051.1 - 2.1e-09 38.0 0.0 5.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain G-alpha PF00503.20 GAK67051.1 - 2.6e-09 36.7 0.5 2.2e-07 30.3 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 GAK67051.1 - 2e-08 34.3 0.0 5.3e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_25 PF13649.6 GAK67051.1 - 1.3e-06 29.0 0.0 3.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Gtr1_RagA PF04670.12 GAK67051.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MTS PF05175.14 GAK67051.1 - 0.00017 21.2 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GTP_EFTU PF00009.27 GAK67051.1 - 0.00063 19.3 0.0 0.062 12.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Methyltransf_11 PF08241.12 GAK67051.1 - 0.0046 17.6 0.0 0.0097 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FeoB_N PF02421.18 GAK67051.1 - 0.021 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Methyltransf_31 PF13847.6 GAK67051.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain TRAPP PF04051.16 GAK67052.1 - 8.7e-40 135.8 0.0 1.1e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SIKE PF05769.11 GAK67053.1 - 0.24 11.3 18.2 0.046 13.7 9.2 2.7 3 0 0 3 3 3 0 SIKE family PBP1_TM PF14812.6 GAK67053.1 - 1.1 9.7 6.0 3.4 8.1 6.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal INCENP_ARK-bind PF03941.15 GAK67053.1 - 2.8 8.0 11.6 32 4.6 0.0 2.8 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region HOOK PF05622.12 GAK67054.1 - 1.7e-55 188.5 52.4 1.7e-55 188.5 52.4 3.3 3 1 1 4 4 4 1 HOOK protein CH PF00307.31 GAK67054.1 - 0.01 16.0 0.2 0.047 13.9 0.0 2.3 2 0 0 2 2 2 0 Calponin homology (CH) domain Sec20 PF03908.13 GAK67054.1 - 1.6 8.7 19.1 0.15 11.9 1.8 4.7 4 1 1 5 5 5 0 Sec20 Pox_A_type_inc PF04508.12 GAK67054.1 - 2.8 8.0 21.5 28 4.8 4.5 5.8 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat NAD_binding_5 PF07994.12 GAK67055.1 - 4.4e-145 483.1 0.0 5.4e-145 482.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAK67055.1 - 1.4e-42 144.3 0.0 2.8e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LLC1 PF14945.6 GAK67055.1 - 0.15 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Cu-oxidase_3 PF07732.15 GAK67056.1 - 9.8e-31 106.2 0.6 2.6e-27 95.2 0.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAK67056.1 - 1.2e-20 74.3 0.0 2.1e-17 63.7 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAK67056.1 - 2.3e-14 53.3 10.8 1.2e-12 47.7 3.9 4.1 3 1 0 3 3 3 1 Multicopper oxidase DIE2_ALG10 PF04922.12 GAK67057.1 - 2.2e-90 303.8 7.2 1.6e-71 241.7 7.4 2.2 2 0 0 2 2 2 2 DIE2/ALG10 family Mito_carr PF00153.27 GAK67058.1 - 1.6e-43 146.6 2.5 4.5e-15 55.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DOT1 PF08123.13 GAK67059.1 - 7.7e-56 188.9 0.0 1.1e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Selenoprotein_S PF06936.11 GAK67059.1 - 0.041 13.7 11.0 0.02 14.7 8.5 1.7 1 1 1 2 2 2 0 Selenoprotein S (SelS) DUF4100 PF13352.6 GAK67059.1 - 3.4 7.4 4.5 5.9 6.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Pkinase PF00069.25 GAK67060.1 - 1.3e-73 247.6 0.0 1.7e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67060.1 - 3.7e-32 111.6 0.0 4.6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK67060.1 - 4.1e-09 36.2 0.0 7e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAK67060.1 - 3e-05 23.0 0.2 9.2e-05 21.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAK67060.1 - 0.002 17.5 0.2 0.0037 16.6 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK67060.1 - 0.01 15.7 0.1 0.021 14.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 GAK67061.1 - 4.5e-70 236.0 0.0 6e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67061.1 - 9.3e-49 166.0 0.0 1.3e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK67061.1 - 1.9e-06 26.9 0.0 4.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAK67061.1 - 0.00046 19.6 0.0 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 GAK67061.1 - 0.052 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC1 family WW PF00397.26 GAK67063.1 - 2e-05 24.6 3.0 3.7e-05 23.7 3.0 1.5 1 0 0 1 1 1 1 WW domain Not1 PF04054.15 GAK67064.1 - 4.7e-122 407.5 0.0 4.7e-122 407.5 0.0 1.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAK67064.1 - 8.8e-96 319.6 0.3 2.2e-95 318.3 0.3 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 GAK67064.1 - 1e-56 190.9 4.3 1e-56 190.9 4.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 GAK67064.1 - 4.2e-54 182.6 0.0 4.2e-54 182.6 0.0 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 GAK67064.1 - 3.6e-44 150.5 0.8 3.6e-44 150.5 0.8 3.2 3 1 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DPBB_1 PF03330.18 GAK67065.1 - 0.014 15.7 0.1 0.065 13.5 0.0 2.2 2 1 0 2 2 2 0 Lytic transglycolase Cofac_haem_bdg PF04187.13 GAK67066.1 - 6.8e-29 101.4 0.0 2.6e-28 99.5 0.0 2.0 1 1 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN EF-hand_4 PF12763.7 GAK67067.1 - 1.7e-37 127.5 0.0 5.2e-15 55.3 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 GAK67067.1 - 3.2e-05 24.3 0.0 0.75 10.3 0.0 3.9 4 0 0 4 4 3 1 EF-hand domain pair UBA PF00627.31 GAK67067.1 - 0.00023 21.0 0.0 0.00084 19.2 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain zf-C4H2 PF10146.9 GAK67067.1 - 0.0015 18.9 6.7 0.0058 17.0 6.7 2.0 1 0 0 1 1 1 1 Zinc finger-containing protein EF-hand_1 PF00036.32 GAK67067.1 - 0.0043 16.5 0.0 3.9 7.2 0.0 4.7 5 0 0 5 5 5 1 EF hand ATG16 PF08614.11 GAK67067.1 - 0.035 14.3 30.4 0.079 13.2 29.1 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) UBA_3 PF09288.10 GAK67067.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Macoilin PF09726.9 GAK67067.1 - 0.068 11.7 14.8 0.11 11.0 14.8 1.2 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 GAK67067.1 - 0.23 10.3 27.2 0.059 12.2 23.4 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 GAK67067.1 - 0.25 11.7 19.2 0.5 10.8 19.2 1.5 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.6 GAK67067.1 - 0.26 9.9 12.9 0.37 9.4 12.9 1.1 1 0 0 1 1 1 0 AAA domain MAD PF05557.13 GAK67067.1 - 0.47 8.8 22.9 0.65 8.3 22.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Atg14 PF10186.9 GAK67067.1 - 1.2 8.1 23.7 0.38 9.8 18.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Allexi_40kDa PF05549.11 GAK67067.1 - 1.2 8.5 6.9 2.5 7.6 6.9 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein CtIP_N PF10482.9 GAK67067.1 - 1.6 8.8 14.8 3.9 7.5 14.8 1.6 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF812 PF05667.11 GAK67067.1 - 1.6 7.5 18.6 2.8 6.7 18.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 GAK67067.1 - 1.8 8.2 22.0 4.2 7.1 21.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF244 PF03112.14 GAK67067.1 - 1.9 8.3 3.1 3.4 7.5 3.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF2730 PF10805.8 GAK67067.1 - 2.7 8.1 12.7 3.3 7.9 5.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TolA_bind_tri PF16331.5 GAK67067.1 - 3.5 7.8 12.8 2.4 8.3 3.5 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation BST2 PF16716.5 GAK67067.1 - 5.8 7.6 17.3 3.5 8.3 4.0 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Synaptobrevin PF00957.21 GAK67067.1 - 7.6 6.4 6.0 13 5.6 6.0 1.3 1 0 0 1 1 1 0 Synaptobrevin Snapin_Pallidin PF14712.6 GAK67067.1 - 8 7.0 18.0 3 8.3 11.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin GAS PF13851.6 GAK67067.1 - 9.4 5.5 26.7 8.7 5.6 11.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PAC2 PF09754.9 GAK67068.1 - 1.6e-25 90.4 0.0 1.9e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Proteasome PF00227.26 GAK67069.1 - 1.5e-50 171.4 0.1 1.8e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 GAK67069.1 - 9.8e-10 37.7 0.1 9.8e-10 37.7 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DUF4116 PF13475.6 GAK67069.1 - 0.048 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) DUF4520 PF15016.6 GAK67069.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Aminotran_4 PF01063.19 GAK67070.1 - 5.1e-30 105.0 0.0 1.5e-29 103.4 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV RNA_POL_M_15KD PF02150.16 GAK67071.1 - 1e-12 47.7 2.6 1e-12 47.7 2.6 3.3 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 GAK67071.1 - 1.9e-11 43.6 4.1 1.1e-09 37.9 0.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 GAK67071.1 - 0.00043 20.3 4.7 4.3 7.5 0.0 3.8 4 0 0 4 4 4 2 Zinc ribbon domain CpXC PF14353.6 GAK67071.1 - 0.0071 16.4 5.3 2.4 8.3 0.8 3.3 1 1 2 3 3 3 1 CpXC protein TackOD1 PF18551.1 GAK67071.1 - 0.0093 15.6 4.3 0.072 12.7 0.2 2.5 2 1 0 2 2 2 1 Thaumarchaeal output domain 1 DZR PF12773.7 GAK67071.1 - 0.012 15.7 8.1 0.061 13.4 0.5 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.6 GAK67071.1 - 0.026 13.9 4.7 0.86 9.0 0.3 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2197 PF09963.9 GAK67071.1 - 0.033 14.4 1.3 0.033 14.4 1.3 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF3268 PF11672.8 GAK67071.1 - 0.078 13.3 1.3 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 GAK67071.1 - 0.091 12.8 7.4 2.6 8.1 0.6 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 GAK67071.1 - 0.37 10.9 4.6 10 6.3 0.5 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_12 PF11331.8 GAK67071.1 - 0.48 10.3 7.7 12 5.9 0.1 3.9 4 0 0 4 4 4 0 Probable zinc-ribbon domain Zn_ribbon_recom PF13408.6 GAK67071.1 - 0.57 10.8 5.5 1 10.0 0.2 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 GAK67071.1 - 0.62 10.5 8.4 0.15 12.5 0.6 2.9 2 2 0 2 2 2 0 Restriction alleviation protein Lar Rpr2 PF04032.16 GAK67071.1 - 0.68 10.2 5.8 10 6.5 5.8 2.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf_UBZ PF18439.1 GAK67071.1 - 0.91 9.2 9.9 4.4 7.0 0.1 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 GAK67071.1 - 1.1 9.3 4.3 0.53 10.3 1.1 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 GAK67071.1 - 1.7 8.4 9.6 13 5.5 0.1 3.9 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-IS66 PF13005.7 GAK67071.1 - 4.9 7.6 9.2 24 5.4 0.1 3.9 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 TF_Zn_Ribbon PF08271.12 GAK67071.1 - 6 6.5 8.3 9 5.9 1.9 3.5 3 1 1 4 4 4 0 TFIIB zinc-binding zf_C2H2_ZHX PF18387.1 GAK67071.1 - 6.3 6.5 7.5 19 5.0 0.1 3.2 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_9 PF14369.6 GAK67071.1 - 7.9 6.8 10.8 5.6 7.3 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon Sel1 PF08238.12 GAK67072.1 - 2.9e-10 40.5 18.5 5.4e-05 23.7 0.2 4.2 4 0 0 4 4 4 3 Sel1 repeat Med7 PF05983.11 GAK67073.1 - 4.3e-54 183.5 0.3 6e-54 183.1 0.3 1.2 1 0 0 1 1 1 1 MED7 protein Aminotran_5 PF00266.19 GAK67074.1 - 6.1e-34 117.6 0.0 2.4e-33 115.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V RF-1 PF00472.20 GAK67075.1 - 2.6e-20 72.5 4.6 5e-20 71.6 4.6 1.4 1 0 0 1 1 1 1 RF-1 domain aGPT-Pplase1 PF18723.1 GAK67076.1 - 2.7e-90 302.6 0.0 6.6e-90 301.3 0.0 1.5 2 0 0 2 2 2 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 GAK67076.1 - 2.4e-05 24.2 0.0 4.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Y_phosphatase2 PF03162.13 GAK67077.1 - 2.3e-41 141.1 0.0 9.4e-41 139.1 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Slx4 PF09494.10 GAK67078.1 - 3e-14 52.7 0.0 6.1e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Glyco_hydro_cc PF11790.8 GAK67079.1 - 6.4e-61 206.0 7.1 7.9e-61 205.7 7.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.17 GAK67079.1 - 0.0016 17.1 0.1 0.017 13.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 39 DUF3824 PF12868.7 GAK67079.1 - 0.24 12.1 4.3 3.7 8.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) PDGF_N PF04692.13 GAK67079.1 - 7.4 7.4 8.7 2.6 8.9 1.6 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region EamA PF00892.20 GAK67080.1 - 2.7e-07 30.8 7.7 2.7e-07 30.8 7.7 3.8 4 0 0 4 4 4 2 EamA-like transporter family CSG2 PF16965.5 GAK67080.1 - 0.00016 20.8 0.0 0.00032 19.8 0.0 1.5 1 0 0 1 1 1 1 Ceramide synthase regulator Sec20 PF03908.13 GAK67081.1 - 1.3e-16 60.3 1.7 1.3e-16 60.3 1.7 2.5 3 0 0 3 3 3 1 Sec20 Uso1_p115_C PF04871.13 GAK67081.1 - 0.9 9.9 16.5 1.2 9.5 3.6 2.9 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region FAA_hydrolase_N PF09298.11 GAK67081.1 - 4.1 7.6 6.3 0.98 9.6 0.9 2.6 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal Ribosomal_L16 PF00252.18 GAK67082.1 - 1.8e-41 141.2 0.1 2.3e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3185 PF11381.8 GAK67083.1 - 0.05 13.6 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) HSCB_C PF07743.13 GAK67084.1 - 2.1e-18 66.6 5.2 3.5e-18 65.8 5.2 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GAK67084.1 - 3.9e-05 23.7 0.0 7.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 GAK67084.1 - 0.065 13.3 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon cwf21 PF08312.12 GAK67084.1 - 0.13 12.5 2.3 0.27 11.4 2.3 1.5 1 0 0 1 1 1 0 cwf21 domain SGTA_dimer PF16546.5 GAK67084.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Homodimerisation domain of SGTA zf-ribbon_3 PF13248.6 GAK67084.1 - 5.6 6.5 6.2 19 4.8 0.6 2.2 1 1 1 2 2 2 0 zinc-ribbon domain PSP1 PF04468.12 GAK67086.1 - 2.7e-29 101.3 0.7 4.1e-29 100.7 0.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF89 PF01937.19 GAK67087.1 - 3.9e-111 371.4 0.0 3.5e-79 266.3 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 Vma12 PF11712.8 GAK67088.1 - 3.2e-33 114.7 0.3 5.8e-33 113.9 0.3 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Phage_tail_APC PF16778.5 GAK67088.1 - 0.089 12.7 1.2 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein DUF4231 PF14015.6 GAK67088.1 - 0.11 12.9 0.9 0.33 11.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PAM2 PF07145.15 GAK67089.1 - 2e-05 23.9 2.8 1.7 8.5 0.0 5.1 5 0 0 5 5 5 2 Ataxin-2 C-terminal region SlyX PF04102.12 GAK67089.1 - 0.0014 19.2 5.2 0.0014 19.2 5.2 6.6 5 2 3 8 8 8 1 SlyX GATA PF00320.27 GAK67091.1 - 2e-06 27.3 2.7 3.3e-06 26.6 2.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Zn_clus PF00172.18 GAK67092.1 - 6.4e-05 23.0 8.9 0.00011 22.2 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.14 GAK67093.1 - 8.5e-07 28.5 10.9 8.5e-07 28.5 10.9 1.7 2 0 0 2 2 2 1 FAR-17a/AIG1-like protein MFAP1 PF06991.11 GAK67094.1 - 1.4e-62 211.3 19.3 1.4e-62 211.3 19.3 3.2 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 GAK67094.1 - 0.16 12.1 1.2 0.39 10.9 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Ras PF00071.22 GAK67095.1 - 1.1e-56 190.9 0.0 1.3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK67095.1 - 1.1e-30 106.3 0.0 1.7e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK67095.1 - 2.8e-12 46.4 0.0 3.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK67095.1 - 3.3e-07 30.4 0.0 6.1e-07 29.5 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAK67095.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAK67095.1 - 0.00017 21.6 0.2 0.0042 17.0 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAK67095.1 - 0.00029 20.4 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAK67095.1 - 0.0026 17.5 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 GAK67095.1 - 0.0062 15.9 0.1 0.076 12.3 0.0 2.2 2 0 0 2 2 2 1 Septin cobW PF02492.19 GAK67095.1 - 0.0074 15.9 0.0 0.021 14.4 0.0 1.7 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAK67095.1 - 0.0081 16.6 0.1 0.02 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 GAK67095.1 - 0.011 15.5 0.3 0.47 10.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 GAK67095.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAK67095.1 - 0.016 14.9 0.0 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 GAK67095.1 - 0.024 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 GAK67095.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 GAK67095.1 - 0.036 14.1 0.0 0.075 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 GAK67095.1 - 0.053 13.4 0.3 0.099 12.5 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 GAK67095.1 - 0.1 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 GAK67095.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 GAK67095.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATG16 PF08614.11 GAK67096.1 - 1.7e-56 191.6 20.3 2.2e-56 191.3 20.3 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4741 PF15897.5 GAK67096.1 - 0.057 13.2 1.3 0.081 12.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4741) DASH_Dam1 PF08653.10 GAK67096.1 - 0.15 11.9 1.7 6.9 6.5 0.3 2.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 XLF PF09302.11 GAK67096.1 - 0.23 11.6 5.7 0.07 13.3 2.3 1.9 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF4407 PF14362.6 GAK67096.1 - 0.38 10.1 14.4 0.61 9.4 14.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 GAK67096.1 - 0.45 9.0 8.5 0.57 8.7 8.5 1.0 1 0 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 GAK67096.1 - 0.47 10.6 11.0 0.17 12.0 6.8 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 GAK67096.1 - 0.73 9.9 15.5 15 5.6 14.6 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 GAK67096.1 - 1.6 9.2 7.5 2 8.9 0.4 3.2 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF3123 PF11321.8 GAK67096.1 - 2.2 9.0 7.2 21 5.8 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) CENP-H PF05837.12 GAK67096.1 - 2.4 8.6 24.6 1.4 9.3 3.4 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 GAK67096.1 - 5.4 7.7 16.8 0.44 11.2 1.9 3.2 2 1 1 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 GAK67096.1 - 9 6.5 24.0 1.3 9.2 7.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Actin PF00022.19 GAK67097.1 - 1.6e-53 181.8 0.0 5.5e-26 91.1 0.0 2.4 2 0 0 2 2 2 2 Actin Nop52 PF05997.12 GAK67098.1 - 3.9e-75 252.3 0.0 6.7e-75 251.6 0.0 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 GTP_EFTU PF00009.27 GAK67098.1 - 3.7e-20 72.3 0.0 7.8e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAK67098.1 - 7.8e-06 26.2 0.7 2e-05 24.9 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAK67098.1 - 0.038 14.1 0.0 0.096 12.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAK67098.1 - 0.2 11.6 0.9 4.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Nop14 PF04147.12 GAK67098.1 - 0.55 8.4 15.4 0.96 7.6 15.4 1.3 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 GAK67098.1 - 6.4 6.4 7.1 13 5.4 7.1 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) MRP-L46 PF11788.8 GAK67099.1 - 5.8e-27 94.8 0.4 1.2e-26 93.8 0.4 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PI3K_1B_p101 PF10486.9 GAK67099.1 - 0.018 12.8 3.7 0.025 12.4 3.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit V-ATPase_H_N PF03224.14 GAK67100.1 - 1.6e-106 356.2 0.0 2.7e-106 355.4 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 GAK67100.1 - 6.2e-38 129.5 0.0 1.4e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.23 GAK67100.1 - 0.00031 20.7 5.7 0.061 13.4 0.2 4.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 GAK67100.1 - 0.1 11.2 0.0 3 6.3 0.0 2.4 2 0 0 2 2 2 0 Adaptin N terminal region SPATA48 PF15073.6 GAK67100.1 - 0.14 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 GSH_synth_ATP PF03917.17 GAK67101.1 - 1.2e-130 435.7 0.0 1.3e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAK67101.1 - 8.2e-33 112.9 0.0 1.6e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Med31 PF05669.12 GAK67102.1 - 1.1e-31 108.7 0.4 1.3e-31 108.4 0.4 1.1 1 0 0 1 1 1 1 SOH1 TPT PF03151.16 GAK67103.1 - 3.2e-20 72.7 17.9 3.9e-20 72.4 17.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAK67103.1 - 2.5e-08 34.2 29.7 4.9e-05 23.5 11.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAK67103.1 - 0.86 8.7 20.8 14 4.7 20.9 2.5 1 1 1 2 2 2 0 UAA transporter family eIF3_subunit PF08597.10 GAK67103.1 - 1.1 9.2 7.3 2.1 8.2 7.3 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit adh_short_C2 PF13561.6 GAK67104.1 - 3.8e-48 164.1 0.0 5e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK67104.1 - 3.4e-43 147.4 0.0 4.1e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK67104.1 - 4.9e-07 29.8 0.0 7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KR domain TPR_1 PF00515.28 GAK67105.1 - 4.5e-55 181.3 26.3 8.5e-08 31.7 0.1 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAK67105.1 - 2.8e-50 164.4 22.0 6.6e-06 25.8 0.1 10.8 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAK67105.1 - 7.8e-38 125.5 16.6 2.4e-05 24.2 0.0 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 GAK67105.1 - 1.2e-26 91.1 19.4 0.00032 20.9 0.4 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAK67105.1 - 3.7e-25 86.0 5.3 0.026 14.5 0.0 9.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAK67105.1 - 4.5e-25 86.2 20.1 0.0005 20.7 0.0 9.6 4 2 6 10 10 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAK67105.1 - 3.2e-24 85.2 17.9 4.8e-06 27.0 0.2 6.7 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAK67105.1 - 5.3e-24 84.3 15.6 2.8e-05 24.3 1.3 7.4 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 GAK67105.1 - 1.1e-21 75.9 11.9 0.0093 16.6 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAK67105.1 - 2.1e-21 75.3 32.6 3.2e-06 26.7 1.9 9.7 4 2 5 9 9 9 5 TPR repeat TPR_9 PF13371.6 GAK67105.1 - 5.9e-19 68.0 9.0 0.0022 18.1 0.2 6.0 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAK67105.1 - 4e-17 62.6 56.1 1.4e-05 25.7 0.8 10.3 8 3 2 11 11 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK67105.1 - 4.5e-11 42.8 7.2 7.4e-07 29.3 1.8 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAK67105.1 - 5.2e-09 35.7 10.5 0.0031 16.8 1.6 5.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 GAK67105.1 - 0.00011 21.9 3.2 4.3 7.0 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 GAK67105.1 - 0.0031 17.3 16.9 3.5 7.6 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF4919 PF16266.5 GAK67105.1 - 0.0032 17.4 0.1 0.32 10.9 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4919) ChAPs PF09295.10 GAK67105.1 - 0.024 13.6 1.2 1.3 8.0 0.2 2.7 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 GAK67105.1 - 0.035 13.8 3.7 1.7 8.3 1.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TOM20_plant PF06552.12 GAK67105.1 - 0.037 13.8 1.0 13 5.5 0.7 3.5 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.6 GAK67105.1 - 0.078 13.3 0.1 0.078 13.3 0.1 4.1 5 1 1 6 6 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 GAK67105.1 - 0.12 12.4 0.3 8.3 6.6 0.0 3.3 3 1 1 4 4 3 0 Rapsyn N-terminal myristoylation and linker region BTAD PF03704.17 GAK67105.1 - 0.33 11.4 12.3 7.2 7.0 0.1 4.4 4 1 0 4 4 3 0 Bacterial transcriptional activator domain DUF5344 PF17279.2 GAK67105.1 - 1.4 9.6 2.5 23 5.7 0.1 3.3 4 0 0 4 4 2 0 Family of unknown function (DUF5344) Fis1_TPR_C PF14853.6 GAK67105.1 - 2.3 8.4 9.3 43 4.3 0.0 5.6 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat DUF1676 PF07898.13 GAK67106.1 - 0.0091 16.0 2.6 0.023 14.7 2.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) Oxysterol_BP PF01237.18 GAK67107.1 - 7.9e-90 301.4 0.3 7.9e-88 294.8 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Phage_stabilise PF11134.8 GAK67107.1 - 0.028 13.3 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Phage stabilisation protein RNR_inhib PF08591.10 GAK67108.1 - 0.056 14.7 0.9 0.14 13.5 0.9 1.8 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor NEXCaM_BD PF16644.5 GAK67108.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin NTF2 PF02136.20 GAK67109.1 - 1.5e-08 35.3 0.0 4.4e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 GAK67109.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Cys_Met_Meta_PP PF01053.20 GAK67110.1 - 6.9e-121 403.4 0.0 9.8e-121 402.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 GAK67110.1 - 5.1e-16 58.7 3.6 2.1e-15 56.7 3.6 2.2 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAK67110.1 - 1.2e-07 32.0 0.9 5e-07 30.0 0.2 2.3 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 GAK67110.1 - 0.0074 15.8 1.7 0.013 15.1 0.3 2.2 2 0 0 2 2 2 1 Galactokinase galactose-binding signature DPBB_1 PF03330.18 GAK67111.1 - 2.3e-05 24.6 0.0 8.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Lytic transglycolase TFIIA PF03153.13 GAK67111.1 - 0.0013 18.9 35.2 0.0019 18.3 35.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Totivirus_coat PF05518.11 GAK67111.1 - 0.032 12.3 11.4 0.042 11.9 11.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein Barwin PF00967.17 GAK67111.1 - 0.032 14.1 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Barwin family Apt1 PF10351.9 GAK67111.1 - 1.1 8.0 12.4 1.6 7.5 12.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 GAK67111.1 - 1.3 6.1 16.3 1.4 5.9 16.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nucleo_P87 PF07267.11 GAK67111.1 - 2.8 6.7 19.5 3.9 6.2 19.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spc7_N PF15402.6 GAK67111.1 - 6.3 4.9 27.2 8.8 4.4 27.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Sec15 PF04091.12 GAK67112.1 - 1.2e-88 297.5 0.0 2.3e-88 296.6 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 GAK67112.1 - 0.00011 22.1 0.8 0.00035 20.5 0.2 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 GAK67112.1 - 0.0007 19.8 1.2 0.0025 18.0 0.2 2.4 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 GAK67112.1 - 0.0041 17.2 0.0 0.018 15.1 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Seryl_tRNA_N PF02403.22 GAK67112.1 - 0.34 11.2 2.4 1.1 9.5 0.1 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 GAK67112.1 - 1.8 8.6 5.3 1 9.5 0.5 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF866 PF05907.13 GAK67114.1 - 1.7e-53 180.7 0.3 1.9e-53 180.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.6 GAK67114.1 - 0.004 17.1 1.8 0.0063 16.5 1.8 1.3 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 GAK67114.1 - 0.2 12.1 5.1 1.1 9.7 4.6 2.0 1 1 1 2 2 2 0 Cytochrome c3 Tyrosinase PF00264.20 GAK67115.1 - 3.3e-19 70.1 5.7 5.6e-19 69.3 5.7 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF423 PF04241.15 GAK67118.1 - 2.9e-24 85.1 0.9 1.4e-23 82.9 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF423) DUF2627 PF11118.8 GAK67118.1 - 0.056 14.0 1.7 0.56 10.8 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Gram_pos_anchor PF00746.21 GAK67118.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif HLH PF00010.26 GAK67119.1 - 4.2e-12 45.8 0.0 1.2e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AMP-binding_C PF13193.6 GAK67119.1 - 8.4e-05 23.5 0.1 0.00087 20.2 0.1 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIIA PF03153.13 GAK67119.1 - 0.23 11.4 6.1 0.33 10.9 6.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 GAK67119.1 - 0.64 8.0 4.1 0.93 7.5 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.18 GAK67119.1 - 0.82 9.5 8.0 1.1 9.0 6.7 1.9 1 1 1 2 2 2 0 Myc amino-terminal region Tom22 PF04281.13 GAK67119.1 - 1.1 9.1 8.0 9.6 6.0 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF4611 PF15387.6 GAK67119.1 - 4.1 7.7 12.6 4 7.7 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 GAK67119.1 - 6.9 4.6 10.1 9.8 4.1 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SNF2_N PF00176.23 GAK67120.1 - 1.7e-60 204.6 0.0 3e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK67120.1 - 2.1e-18 66.7 0.0 1.4e-17 64.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 GAK67120.1 - 1.5e-11 44.4 11.6 1.5e-11 44.4 11.6 3.2 3 0 0 3 3 3 1 HSA ResIII PF04851.15 GAK67120.1 - 6.5e-09 36.0 0.0 1.6e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_1 PF00232.18 GAK67120.1 - 0.24 9.7 0.8 0.39 9.1 0.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Dabb PF07876.12 GAK67121.1 - 2.1e-14 53.9 0.0 2.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Zn_clus PF00172.18 GAK67122.1 - 7e-09 35.7 8.4 1.2e-08 34.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP90 PF00183.18 GAK67122.1 - 0.22 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Hsp90 protein DEAD PF00270.29 GAK67123.1 - 2.9e-45 154.2 0.4 5e-45 153.4 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK67123.1 - 3e-32 111.3 0.2 4.8e-31 107.4 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK67123.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAK67123.1 - 0.00075 19.9 0.1 0.0041 17.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAK67123.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 GAK67123.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 GAK67123.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase zf-C3HC4_3 PF13920.6 GAK67124.1 - 2.4e-07 30.5 6.3 2.4e-07 30.5 6.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK67124.1 - 0.0044 16.8 9.8 0.0044 16.8 9.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK67124.1 - 1.8 8.5 18.0 0.048 13.5 8.8 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Chitin_synth_2 PF03142.15 GAK67125.1 - 7.6e-244 810.2 0.1 1.1e-243 809.6 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase DASH_Dad1 PF08649.10 GAK67125.1 - 1.3e-21 76.5 0.0 2.6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad1 Glyco_trans_2_3 PF13632.6 GAK67125.1 - 2e-11 44.2 5.2 2e-11 44.2 5.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK67125.1 - 1e-10 41.9 0.4 3.8e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAK67125.1 - 0.0091 15.5 0.1 1.7 8.1 0.1 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 DSPc PF00782.20 GAK67127.1 - 1.3e-07 31.5 0.0 4.1e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 GAK67127.1 - 0.0027 17.4 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 GAK67127.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAK67127.1 - 0.024 14.2 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein-tyrosine phosphatase BSD PF03909.17 GAK67128.1 - 9.5e-21 73.6 0.3 7.1e-15 54.8 0.0 2.9 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 GAK67128.1 - 1.3e-15 57.5 0.1 3e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain ORC6 PF05460.13 GAK67128.1 - 0.22 10.8 6.1 0.45 9.7 6.1 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NAM-associated PF14303.6 GAK67128.1 - 3.1 8.5 5.0 9 7.0 5.0 1.9 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Hid1 PF12722.7 GAK67129.1 - 1.5e-140 469.9 0.0 8e-140 467.5 0.0 2.0 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAK67129.1 - 1.1e-74 252.0 0.0 1.7e-74 251.4 0.0 1.2 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein GET2 PF08690.10 GAK67130.1 - 6.7e-18 65.4 0.7 1.9e-08 34.4 0.1 2.5 2 1 0 2 2 2 2 GET complex subunit GET2 PMT PF02366.18 GAK67131.1 - 3.1e-74 249.6 18.2 5.2e-74 248.9 18.2 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAK67131.1 - 3.6e-57 193.2 13.9 8.7e-57 191.9 13.9 1.7 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAK67131.1 - 1.3e-24 87.1 0.4 2.2e-24 86.3 0.4 1.3 1 0 0 1 1 1 1 MIR domain DUF3955 PF13127.6 GAK67132.1 - 8.3e-05 22.3 1.0 0.00036 20.3 1.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3955) FA_desaturase PF00487.24 GAK67132.1 - 0.19 11.5 2.5 0.32 10.8 0.0 2.5 3 0 0 3 3 3 0 Fatty acid desaturase EamA PF00892.20 GAK67132.1 - 0.46 10.6 30.1 0.35 11.0 5.4 3.2 3 0 0 3 3 3 0 EamA-like transporter family NAC PF01849.18 GAK67133.1 - 5.5e-20 71.1 0.0 1.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 NAC domain Spore_coat_CotO PF14153.6 GAK67133.1 - 0.35 10.8 5.1 0.58 10.1 5.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CSRNP_N PF16019.5 GAK67133.1 - 1.3 8.9 4.2 1.8 8.4 1.3 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus YbaB_DNA_bd PF02575.16 GAK67133.1 - 2.7 8.3 13.0 1 9.6 10.1 1.8 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family MRNIP PF15749.5 GAK67133.1 - 3.6 8.4 6.2 11 6.8 3.1 2.2 2 1 0 2 2 2 0 MRN-interacting protein PGA2 PF07543.12 GAK67133.1 - 4.3 7.3 9.3 1.1 9.3 4.5 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 Fe-S_biosyn PF01521.20 GAK67134.1 - 2e-14 53.7 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CDC37_N PF03234.14 GAK67135.1 - 9.9e-40 136.4 1.1 9.9e-40 136.4 1.1 2.6 1 1 1 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 GAK67135.1 - 3.9e-24 84.8 0.0 7.2e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 GAK67135.1 - 1.3e-20 73.3 0.2 5.2e-20 71.4 0.2 2.1 1 0 0 1 1 1 1 Cdc37 C terminal domain COG7 PF10191.9 GAK67136.1 - 1.4e-36 126.1 11.2 5.6e-34 117.5 9.4 2.5 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) Exo84_C PF16528.5 GAK67136.1 - 0.023 14.5 0.2 0.063 13.1 0.2 1.8 1 0 0 1 1 1 0 Exocyst component 84 C-terminal RNase_PH PF01138.21 GAK67137.1 - 6.5e-22 78.5 0.2 1.3e-21 77.4 0.2 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAK67137.1 - 0.012 15.6 0.0 0.041 13.9 0.0 2.0 2 1 0 2 2 2 0 3' exoribonuclease family, domain 2 PUF PF00806.19 GAK67138.1 - 1e-16 59.6 0.0 9.7e-05 21.9 0.0 4.9 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat MyTH4 PF00784.17 GAK67138.1 - 0.038 14.5 0.2 0.089 13.3 0.2 1.7 1 0 0 1 1 1 0 MyTH4 domain SH3BGR PF04908.15 GAK67139.1 - 3.5e-08 33.5 0.0 8.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein COX4 PF02936.14 GAK67140.1 - 6.1e-30 104.0 0.4 2.3e-21 76.3 0.0 2.4 2 0 0 2 2 2 2 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.10 GAK67140.1 - 0.46 11.1 3.2 4.4 8.0 0.1 2.5 1 1 1 2 2 2 0 HMG-box domain HAD_2 PF13419.6 GAK67141.1 - 8.2e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAK67141.1 - 5.1e-08 33.5 0.0 2.7e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAK67141.1 - 4.9e-05 23.3 0.0 0.00023 21.1 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Ion_trans PF00520.31 GAK67142.1 - 7.6e-123 408.5 68.2 3.9e-38 131.1 3.8 5.1 5 0 0 5 5 5 5 Ion transport protein PKD_channel PF08016.12 GAK67142.1 - 0.00059 18.6 7.9 0.00059 18.6 7.9 7.1 7 2 1 8 8 8 4 Polycystin cation channel Proteasome PF00227.26 GAK67143.1 - 4.8e-59 199.0 0.2 6.3e-59 198.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAK67143.1 - 3e-14 52.4 0.3 1e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_M55 PF04951.13 GAK67143.1 - 0.018 14.5 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 D-aminopeptidase SNARE_assoc PF09335.11 GAK67144.1 - 8.2e-12 45.7 2.6 2.1e-11 44.3 2.6 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein PCI PF01399.27 GAK67144.1 - 7.7e-10 39.2 0.8 2.2e-09 37.8 0.2 2.3 2 0 0 2 2 2 1 PCI domain Peptidase_M15_2 PF05951.13 GAK67144.1 - 0.16 11.6 2.0 0.54 9.9 0.0 2.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF882) DUF3439 PF11921.8 GAK67144.1 - 0.67 9.9 12.5 1.6 8.7 12.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF382 PF04037.13 GAK67145.1 - 4.7e-57 191.6 0.7 4.7e-57 191.6 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 GAK67145.1 - 4.1e-18 65.0 2.7 9.1e-18 63.9 2.7 1.6 1 0 0 1 1 1 1 PSP Trypan_PARP PF05887.11 GAK67145.1 - 0.7 9.9 10.4 2 8.4 10.4 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) hNIFK_binding PF12196.8 GAK67145.1 - 7 6.2 6.9 9.4 5.8 0.0 3.0 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK DSPc PF00782.20 GAK67147.1 - 9.4e-22 77.3 0.0 3.1e-18 65.9 0.1 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAK67147.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MFS_1 PF07690.16 GAK67148.1 - 9.2e-24 84.0 41.9 2.7e-23 82.5 41.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK67148.1 - 5.2e-08 32.2 3.3 5.2e-08 32.2 3.3 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter AMP-binding PF00501.28 GAK67149.1 - 8e-68 228.9 0.0 1.1e-67 228.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme JmjC PF02373.22 GAK67152.1 - 6e-39 133.0 0.1 6e-39 133.0 0.1 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 GAK67152.1 - 5.9e-14 51.7 0.0 1.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.6 GAK67152.1 - 1.6e-09 37.9 1.9 4.2e-09 36.5 1.9 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAK67152.1 - 3.2e-09 36.9 2.6 8e-09 35.6 2.6 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.8 GAK67152.1 - 0.16 12.2 1.7 0.36 11.0 1.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 GAK67152.1 - 0.31 11.0 1.6 0.84 9.6 1.6 1.7 1 0 0 1 1 1 0 PHD-finger UBA PF00627.31 GAK67153.1 - 2.1e-05 24.3 0.0 7e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 GAK67153.1 - 0.0014 18.8 0.3 0.0031 17.6 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain UPF0121 PF03661.13 GAK67154.1 - 3.7e-48 164.0 6.3 4.7e-48 163.7 6.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CPBP PF02517.16 GAK67154.1 - 0.13 12.6 7.5 0.33 11.4 1.0 2.4 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease FadA PF09403.10 GAK67155.1 - 0.055 13.9 1.4 0.18 12.3 0.3 2.1 2 0 0 2 2 2 0 Adhesion protein FadA TPR_12 PF13424.6 GAK67156.1 - 8.4e-16 58.0 23.9 0.0025 18.1 0.1 9.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAK67156.1 - 1.1e-06 28.2 14.5 0.045 13.8 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAK67156.1 - 1.3e-05 25.6 10.5 0.034 15.0 0.1 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAK67156.1 - 0.00017 22.0 0.6 1.5 9.4 0.3 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAK67156.1 - 0.00038 20.5 2.0 9 6.8 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_22 PF13401.6 GAK67156.1 - 0.0011 19.2 0.1 0.018 15.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAK67156.1 - 0.0061 17.1 0.0 0.034 14.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK67156.1 - 0.0067 16.8 0.7 0.0067 16.8 0.7 3.3 3 0 0 3 3 3 1 AAA ATPase domain TPR_2 PF07719.17 GAK67156.1 - 0.015 15.4 17.9 2.6 8.4 0.0 7.5 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAK67156.1 - 0.027 14.3 13.3 3.6 7.6 0.2 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK67156.1 - 0.031 14.9 4.2 5.7 7.8 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NACHT PF05729.12 GAK67156.1 - 0.14 12.1 0.5 2.7 7.9 0.0 2.9 2 0 0 2 2 2 0 NACHT domain TPR_16 PF13432.6 GAK67156.1 - 3.6 8.3 7.0 1.8 9.3 1.3 3.5 3 1 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK67156.1 - 4.6 7.5 15.3 1 9.6 0.0 6.0 7 0 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GAK67156.1 - 8.8 6.3 10.4 28 4.7 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAK67159.1 - 3.1e-17 62.5 96.2 4.3e-16 58.8 57.1 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily Bacillus_PapR PF05968.11 GAK67159.1 - 0.0054 16.6 1.2 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 Bacillus PapR protein CMD PF02627.20 GAK67160.1 - 6.5e-20 71.0 0.2 3.1e-19 68.8 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Methyltransf_24 PF13578.6 GAK67160.1 - 0.00012 23.0 0.0 0.00027 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_RNA PF04452.14 GAK67160.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Ribosomal_60s PF00428.19 GAK67160.1 - 10 6.8 9.1 0.75 10.4 2.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LPMO_10 PF03067.15 GAK67161.1 - 9.1e-32 111.3 0.4 9.1e-32 111.3 0.4 1.8 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Macoilin PF09726.9 GAK67161.1 - 4 5.9 10.6 4.9 5.6 10.6 1.1 1 0 0 1 1 1 0 Macoilin family adh_short PF00106.25 GAK67162.1 - 6.2e-26 91.1 0.0 1.3e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Nop25 PF09805.9 GAK67162.1 - 1.4e-22 80.6 14.1 1.4e-22 80.6 14.1 3.3 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) adh_short_C2 PF13561.6 GAK67162.1 - 8.1e-17 61.6 0.0 3.2e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK67162.1 - 0.00058 19.8 0.0 0.0021 18.0 0.0 1.9 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.22 GAK67162.1 - 0.0051 16.6 0.0 0.025 14.4 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.22 GAK67162.1 - 3.7 7.2 7.0 33 4.1 7.0 2.3 1 1 0 1 1 1 0 Ribosomal protein L4/L1 family Abhydrolase_3 PF07859.13 GAK67164.1 - 8.8e-59 198.9 0.2 1.2e-58 198.5 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAK67164.1 - 2.8e-06 27.0 0.1 4.8e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 GAK67164.1 - 7e-06 25.2 0.1 2e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAK67164.1 - 0.0015 17.5 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.20 GAK67164.1 - 0.0098 15.6 0.3 0.46 10.1 0.3 2.2 1 1 0 1 1 1 1 Putative esterase Cytochrom_C_2 PF01322.20 GAK67164.1 - 0.1 13.5 0.1 2 9.3 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C' AXE1 PF05448.12 GAK67164.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 GAK67164.1 - 0.21 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Retrotran_gag_2 PF14223.6 GAK67165.1 - 2.1e-10 40.4 0.5 2.8e-10 40.0 0.5 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 GAK67165.1 - 1.4e-06 28.5 0.1 2.5e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1642 PF07852.11 GAK67165.1 - 0.045 14.3 0.3 0.35 11.4 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1642) DUF4276 PF14103.6 GAK67165.1 - 0.061 13.5 0.4 7 6.8 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4276) DUF2721 PF11026.8 GAK67165.1 - 0.14 12.1 0.1 0.6 10.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Jnk-SapK_ap_N PF09744.9 GAK67165.1 - 0.19 12.0 2.7 0.42 10.8 0.2 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Cep57_MT_bd PF06657.13 GAK67165.1 - 1.7 9.1 4.5 16 6.0 0.3 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Cyt-b5 PF00173.28 GAK67166.1 - 3.8e-18 65.4 0.1 5.9e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.22 GAK67167.1 - 3.8e-70 236.9 0.0 4.8e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.13 GAK67169.1 - 9.3e-24 84.3 12.4 2.1e-23 83.1 12.4 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Tgi2PP PF18250.1 GAK67170.1 - 0.17 12.2 0.6 0.37 11.0 0.1 1.8 2 0 0 2 2 2 0 Effector immunity protein Tgi2PP Abhydrolase_1 PF00561.20 GAK67171.1 - 7e-18 65.2 0.0 8.1e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAK67171.1 - 3.8e-16 59.1 0.0 7.4e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hep_59 PF07052.11 GAK67172.1 - 2.6e-26 92.5 2.8 2.8e-26 92.3 0.4 2.4 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Glutaredoxin PF00462.24 GAK67172.1 - 5.1e-12 45.8 0.0 6.5e-11 42.3 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 GAK67172.1 - 0.084 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GvpG PF05120.12 GAK67172.1 - 0.11 12.5 0.5 0.4 10.7 0.5 2.0 1 1 0 1 1 1 0 Gas vesicle protein G SBDS_C PF09377.10 GAK67173.1 - 2e-37 127.8 0.1 3.3e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 GAK67173.1 - 1.6e-35 121.0 0.5 4.5e-35 119.6 0.3 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Capsid_N PF16903.5 GAK67173.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Major capsid protein N-terminus PMT PF02366.18 GAK67174.1 - 1.4e-79 267.1 16.2 2.8e-79 266.2 16.2 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAK67174.1 - 1.8e-65 220.3 6.3 1.8e-65 220.3 6.3 2.7 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAK67174.1 - 6.2e-21 75.1 0.9 1.1e-20 74.2 0.9 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 GAK67174.1 - 5.6e-06 26.7 10.6 5.6e-06 26.7 10.6 2.7 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.32 GAK67175.1 - 1.6e-41 139.5 10.5 1.2e-06 29.1 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK67175.1 - 5.2e-14 52.3 0.0 0.002 18.4 0.0 5.5 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 GAK67175.1 - 4.1e-13 48.6 6.7 7.5e-13 47.8 6.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 GAK67175.1 - 2e-07 30.3 0.0 0.033 13.2 0.0 3.4 2 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAK67175.1 - 0.00092 18.6 0.0 0.84 8.9 0.0 2.5 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 GAK67175.1 - 0.0045 15.7 2.8 2 7.0 0.1 4.0 3 1 2 5 5 5 2 Nucleoporin Nup120/160 SCHIP-1 PF10148.9 GAK67175.1 - 0.0085 15.7 0.7 0.013 15.1 0.7 1.2 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 Nbas_N PF15492.6 GAK67175.1 - 0.023 14.1 0.1 0.65 9.3 0.0 3.0 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal EBP50_C PF09007.11 GAK67175.1 - 0.089 13.8 1.0 0.16 13.0 1.0 1.3 1 0 0 1 1 1 0 EBP50, C-terminal Bestrophin PF01062.21 GAK67176.1 - 4.2e-38 131.4 0.0 7e-38 130.7 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.18 GAK67177.1 - 0.00063 19.8 6.6 0.0012 19.0 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.24 GAK67178.1 - 8.4e-18 63.8 33.1 0.00013 21.7 0.7 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK67178.1 - 1.7e-14 53.3 32.5 6.4e-06 26.1 2.7 5.6 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 GAK67178.1 - 8.7e-09 36.1 21.7 0.00012 22.7 0.4 5.1 1 1 4 5 5 5 4 Torus domain zf-CCHC PF00098.23 GAK67178.1 - 5.3e-06 26.3 3.7 5.3e-06 26.3 1.0 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_4 PF18044.1 GAK67178.1 - 6.8e-05 22.6 0.5 6.8e-05 22.6 0.5 4.7 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 GAK67178.1 - 0.079 13.2 16.3 0.8 9.9 3.4 3.9 1 1 2 3 3 3 0 Zinc-finger containing family Ribosomal_L24e PF01246.20 GAK67179.1 - 9.8e-31 105.8 6.4 1.8e-30 104.9 6.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e HAGH_C PF16123.5 GAK67179.1 - 0.095 13.2 2.3 0.12 12.9 1.0 1.8 1 1 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus HMMR_C PF15908.5 GAK67180.1 - 0.038 14.2 0.4 0.066 13.5 0.4 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Myb_DNA-bind_5 PF13873.6 GAK67180.1 - 0.12 12.4 2.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Amino_oxidase PF01593.24 GAK67181.1 - 2.6e-62 211.6 0.0 4.2e-62 210.9 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK67181.1 - 1.8e-13 50.5 0.1 4.3e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAK67181.1 - 6.1e-06 25.7 0.2 1.6e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK67181.1 - 7.1e-06 25.4 0.8 1.4e-05 24.4 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAK67181.1 - 1.7e-05 23.7 0.2 0.00013 20.8 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAK67181.1 - 3.6e-05 23.1 0.4 7.3e-05 22.1 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 GAK67181.1 - 3.8e-05 24.2 0.2 0.00011 22.7 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK67181.1 - 8.6e-05 22.3 0.3 0.00025 20.8 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAK67181.1 - 0.00016 21.2 0.1 0.0003 20.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAK67181.1 - 0.00025 20.4 0.7 0.00044 19.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GAK67181.1 - 0.0011 18.2 0.4 0.022 13.9 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAK67181.1 - 0.0017 17.7 0.2 0.22 10.8 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAK67181.1 - 0.0056 15.8 0.4 0.012 14.7 0.4 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAK67181.1 - 0.006 16.6 0.3 0.61 10.1 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAK67181.1 - 0.047 13.0 0.2 0.082 12.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_4 PF07993.12 GAK67182.1 - 1.6e-30 106.1 0.0 2.2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAK67182.1 - 0.00019 21.0 0.1 0.0003 20.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAK67182.1 - 0.015 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 GAK67182.1 - 0.021 15.1 0.0 0.43 10.8 0.1 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 GAK67182.1 - 0.052 14.0 0.1 0.13 12.7 0.1 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 GAK67183.1 - 1.1e-34 120.0 43.5 2.8e-34 118.6 43.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAK67183.1 - 9.6e-08 30.9 18.5 1.8e-07 30.0 18.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nramp PF01566.18 GAK67184.1 - 1.2e-91 307.4 12.0 2.8e-51 174.6 1.4 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Mobilization_B PF17511.2 GAK67184.1 - 0.1 12.9 1.4 2.3 8.6 0.2 2.9 2 0 0 2 2 2 0 Mobilization protein B CPP1-like PF11833.8 GAK67184.1 - 0.2 11.3 3.7 0.62 9.7 2.9 2.3 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Wzy_C PF04932.15 GAK67184.1 - 2.9 7.5 8.6 18 5.0 4.5 3.3 3 1 0 3 3 3 0 O-Antigen ligase DUF1996 PF09362.10 GAK67185.1 - 5.4e-66 222.9 0.1 5.4e-66 222.9 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Mucin PF01456.17 GAK67185.1 - 1.1 9.2 22.2 6.4 6.8 0.2 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein SRP-alpha_N PF04086.13 GAK67185.1 - 3.4 7.5 9.6 4.8 7.0 9.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zn_clus PF00172.18 GAK67186.1 - 0.0054 16.8 6.5 0.0093 16.1 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 GAK67187.1 - 3.1e-33 113.3 31.3 6e-07 30.1 0.2 9.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK67187.1 - 5.9e-13 48.9 2.3 0.034 14.4 0.0 6.7 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAK67187.1 - 7.5e-10 38.6 0.5 2.1e-09 37.1 0.5 1.9 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 GAK67187.1 - 6.4e-09 35.6 0.0 0.0067 15.8 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 GAK67187.1 - 3.4e-07 29.3 4.4 0.22 10.1 0.0 5.5 4 1 0 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.33 GAK67187.1 - 7.8e-05 22.4 1.4 0.00017 21.4 1.4 1.6 1 0 0 1 1 1 1 F-box domain DUF5046 PF16465.5 GAK67187.1 - 0.006 16.1 0.0 2.2 7.7 0.0 3.2 1 1 3 4 4 4 1 Domain of unknown function (DUF5046) Tic110 PF16940.5 GAK67187.1 - 0.096 11.2 0.0 0.18 10.2 0.0 1.4 1 0 0 1 1 1 0 Chloroplast envelope transporter PQQ_2 PF13360.6 GAK67187.1 - 0.16 11.5 4.0 1.3 8.5 0.1 3.2 2 1 1 3 3 3 0 PQQ-like domain PQQ_3 PF13570.6 GAK67187.1 - 0.19 12.3 5.0 51 4.5 0.1 5.3 3 1 2 5 5 5 0 PQQ-like domain PseudoU_synth_1 PF01416.20 GAK67188.1 - 3.1e-10 40.5 0.0 1.5e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase EF-1_beta_acid PF10587.9 GAK67188.1 - 1.4 9.4 9.1 0.81 10.2 3.7 2.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region TPR_1 PF00515.28 GAK67189.1 - 1.2e-31 107.2 10.6 6.9e-06 25.7 0.2 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAK67189.1 - 1.2e-29 100.0 17.9 2.1e-05 24.3 0.0 8.5 9 0 0 9 9 8 6 Tetratricopeptide repeat DnaJ PF00226.31 GAK67189.1 - 4.4e-22 78.0 3.3 9.2e-22 77.0 3.3 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 GAK67189.1 - 8.1e-19 67.9 25.2 5.1e-06 26.9 2.4 6.3 3 1 2 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAK67189.1 - 9.5e-18 62.9 8.0 0.043 14.0 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAK67189.1 - 4.1e-17 62.6 21.4 2e-07 31.5 0.4 5.4 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAK67189.1 - 2.9e-16 59.5 18.9 1.7e-05 25.0 2.1 6.0 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAK67189.1 - 3.8e-16 58.4 21.5 0.0002 21.9 0.6 8.0 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAK67189.1 - 5.9e-13 48.3 7.6 0.00094 18.8 0.0 6.1 5 1 1 6 6 6 4 TPR repeat TPR_17 PF13431.6 GAK67189.1 - 2.5e-11 43.1 6.4 0.041 14.3 0.1 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAK67189.1 - 3.1e-11 42.5 6.0 0.084 12.9 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK67189.1 - 1e-09 38.4 20.9 2.3e-05 24.5 2.4 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK67189.1 - 1.5e-07 31.5 11.9 0.11 12.7 0.2 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAK67189.1 - 7.5e-06 26.3 7.8 3.1 8.6 0.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAK67189.1 - 0.0043 17.5 11.4 0.25 12.1 0.4 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.17 GAK67189.1 - 0.022 15.2 25.4 0.16 12.4 11.4 5.0 2 2 1 4 4 4 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 GAK67189.1 - 0.035 13.6 3.3 0.054 13.0 0.1 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 GAK67189.1 - 0.039 13.8 16.5 1.2 9.1 0.2 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAK67189.1 - 0.06 13.4 0.9 18 5.4 0.1 3.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 Coatomer_E PF04733.14 GAK67189.1 - 0.11 11.9 0.1 0.11 11.9 0.1 3.8 3 1 2 5 5 5 0 Coatomer epsilon subunit DUF3856 PF12968.7 GAK67189.1 - 0.12 12.4 13.0 0.084 12.9 5.3 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) AAA_lid_7 PF17867.1 GAK67189.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Midasin AAA lid domain SOG2 PF10428.9 GAK67189.1 - 0.75 8.9 7.0 1.1 8.3 7.0 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Fis1_TPR_C PF14853.6 GAK67189.1 - 1 9.5 0.0 1 9.5 0.0 4.5 4 2 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 GAK67189.1 - 1.5 8.9 13.6 11 6.1 3.0 4.6 4 1 0 4 4 4 0 Protein of unknown function (DUF627) NRBF2_MIT PF17169.4 GAK67189.1 - 9.6 6.5 10.1 1 9.7 0.3 3.2 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 AP_endonuc_2 PF01261.24 GAK67190.1 - 1.5e-23 83.4 0.0 3.8e-22 78.8 0.0 2.2 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.11 GAK67191.1 - 2.7e-09 37.2 0.0 6.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAK67191.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 GAK67192.1 - 6e-117 391.3 20.3 6.9e-117 391.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK67192.1 - 6.7e-29 100.9 27.5 6.7e-29 100.9 27.5 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Plus-3 PF03126.18 GAK67193.1 - 1.3e-21 77.1 0.0 3.5e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain Beta-lactamase PF00144.24 GAK67193.1 - 0.49 9.6 6.8 0.054 12.7 0.9 2.3 3 0 0 3 3 3 0 Beta-lactamase PGA2 PF07543.12 GAK67195.1 - 1.7 8.6 5.9 9.6 6.2 0.5 2.5 2 1 1 3 3 3 0 Protein trafficking PGA2 UCH PF00443.29 GAK67198.1 - 2.3e-63 214.1 0.0 4e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAK67198.1 - 1.8e-15 57.4 0.0 5.8e-14 52.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 GAK67198.1 - 3.2e-07 30.5 0.1 7e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 GAK67198.1 - 0.0065 17.0 0.0 0.026 15.0 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 GAK67198.1 - 0.022 14.5 0.5 0.045 13.5 0.5 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DivIVA PF05103.13 GAK67198.1 - 0.17 12.0 2.4 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 DivIVA protein ATG16 PF08614.11 GAK67198.1 - 1.2 9.3 13.0 3.8 7.7 13.0 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Aldedh PF00171.22 GAK67199.1 - 2.7e-159 530.6 0.0 3.1e-159 530.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAK67199.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Polysacc_deac_1 PF01522.21 GAK67200.1 - 2.5e-16 59.7 0.0 3.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 GAK67200.1 - 0.00017 21.3 0.2 0.00029 20.6 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 GAK67200.1 - 0.014 13.8 0.0 0.021 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) PX PF00787.24 GAK67201.1 - 9.4e-13 48.1 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 PX domain NPV_P10 PF05531.12 GAK67201.1 - 3.5 8.2 6.5 2.1 8.8 2.5 2.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Actin PF00022.19 GAK67202.1 - 3.1e-111 371.9 0.0 1.4e-110 369.7 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAK67202.1 - 0.02 13.7 0.0 0.074 11.9 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Sec34 PF04136.15 GAK67203.1 - 2e-29 102.4 0.2 2e-29 102.4 0.2 2.9 3 0 0 3 3 3 1 Sec34-like family DUF632 PF04782.12 GAK67203.1 - 0.018 14.4 1.8 0.047 13.0 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF632) SUIM_assoc PF16619.5 GAK67203.1 - 0.079 13.0 8.3 0.26 11.4 8.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DinB_2 PF12867.7 GAK67203.1 - 0.12 12.9 6.7 0.083 13.4 2.2 3.2 2 1 0 2 2 2 0 DinB superfamily SPARC_Ca_bdg PF10591.9 GAK67203.1 - 0.14 12.5 0.9 0.38 11.1 0.9 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Exo70 PF03081.15 GAK67203.1 - 0.15 11.1 3.5 3.7 6.5 0.0 3.2 3 0 0 3 3 3 0 Exo70 exocyst complex subunit DUF3037 PF11236.8 GAK67203.1 - 0.7 10.3 6.7 0.13 12.7 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) Lsr2 PF11774.8 GAK67203.1 - 1.1 9.4 4.4 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Lsr2 CNOT1_HEAT PF16418.5 GAK67203.1 - 2.2 8.4 6.0 0.8 9.8 2.5 2.1 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat CAP_N PF01213.19 GAK67204.1 - 0.59 9.6 7.1 0.84 9.1 7.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PCNA_N PF00705.18 GAK67205.1 - 8.6e-48 161.2 1.6 1.5e-47 160.4 1.2 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 GAK67205.1 - 9.5e-44 148.7 0.5 7e-22 78.0 0.1 2.6 2 1 1 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 GAK67205.1 - 0.00023 20.7 0.0 0.0011 18.5 0.0 2.3 1 1 0 1 1 1 1 Rad9 Bac_A_amyl_C PF18612.1 GAK67205.1 - 0.084 12.7 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain WD40 PF00400.32 GAK67206.1 - 2.2e-25 88.4 7.4 0.00019 22.2 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PFU PF09070.11 GAK67206.1 - 2.4e-10 40.6 0.0 4.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Fungal_trans PF04082.18 GAK67207.1 - 3.1e-07 29.7 0.1 7.8e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK67207.1 - 0.00022 21.3 7.0 0.00037 20.5 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCC1_2 PF13540.6 GAK67208.1 - 8.2e-13 47.8 15.4 0.00024 20.8 0.0 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAK67208.1 - 2.6e-10 40.7 5.3 0.17 12.5 0.0 6.8 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 GAK67208.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.16 GAK67210.1 - 1.3e-29 103.2 22.3 3.4e-29 101.9 22.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK67210.1 - 4.6e-28 98.3 18.4 2e-26 92.9 18.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Polyketide_cyc PF03364.20 GAK67211.1 - 1.2e-26 93.5 0.1 2e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAK67211.1 - 1.5e-07 31.8 0.4 3.3e-07 30.7 0.4 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Epimerase PF01370.21 GAK67211.1 - 1.6e-05 24.5 0.0 8.6e-05 22.1 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAK67211.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GAK67211.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Peptidase_C53 PF05550.11 GAK67211.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 MFS_1 PF07690.16 GAK67212.1 - 1e-34 120.0 37.8 1.9e-34 119.1 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex2_Pex12 PF04757.14 GAK67212.1 - 2.6 7.6 5.9 0.44 10.1 1.3 1.9 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region RRM_1 PF00076.22 GAK67213.1 - 3.3e-08 33.2 0.2 0.0012 18.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK67213.1 - 0.063 13.4 0.1 6.6 6.9 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif GPI-anchored PF10342.9 GAK67214.1 - 0.12 13.2 0.1 0.28 12.0 0.1 1.6 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tim17 PF02466.19 GAK67215.1 - 5.2e-08 33.2 0.6 1.2e-07 32.0 0.2 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Amnionless PF14828.6 GAK67216.1 - 0.018 13.9 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 Amnionless Phage_Coat_Gp8 PF05371.12 GAK67216.1 - 0.052 13.3 0.7 0.13 12.1 0.7 1.7 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Presenilin PF01080.17 GAK67216.1 - 0.072 11.8 5.0 0.12 11.1 5.0 1.3 1 0 0 1 1 1 0 Presenilin DUF4366 PF14283.6 GAK67216.1 - 0.34 10.9 3.4 1.9 8.5 3.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Mucin15 PF15672.5 GAK67216.1 - 0.74 9.2 31.5 1.1 8.6 31.5 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 5TM-5TMR_LYT PF07694.12 GAK67216.1 - 0.93 9.0 4.1 8 5.9 0.1 2.6 3 0 0 3 3 3 0 5TMR of 5TMR-LYT ASD2 PF08687.11 GAK67216.1 - 4.4 6.8 7.1 6.8 6.2 7.1 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 GREB1 PF15782.5 GAK67216.1 - 7.3 3.6 16.8 9.5 3.2 16.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPP4R2 PF09184.11 GAK67216.1 - 9.5 5.7 13.3 15 5.1 13.3 1.3 1 0 0 1 1 1 0 PPP4R2 Ribosomal_L28e PF01778.17 GAK67217.1 - 1.4e-38 132.1 1.5 1.4e-38 132.1 1.5 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 GAK67217.1 - 2e-26 92.5 27.3 2e-26 92.5 27.3 2.2 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 GAK67217.1 - 0.00031 20.2 22.3 0.00041 19.8 22.3 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 GAK67217.1 - 0.0029 17.4 1.5 0.0046 16.7 1.5 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain G-alpha PF00503.20 GAK67219.1 - 4.8e-84 282.5 0.0 5.7e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAK67219.1 - 1.6e-11 44.0 0.0 4.6e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.6 GAK67219.1 - 0.00082 19.7 0.0 0.0037 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAK67219.1 - 0.0018 18.8 0.0 0.0037 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 GAK67219.1 - 0.0033 17.1 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK67219.1 - 0.011 16.1 1.3 0.082 13.3 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 GAK67219.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAK67219.1 - 0.021 14.7 0.0 0.89 9.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 GAK67219.1 - 0.022 14.3 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 GAK67219.1 - 0.034 14.4 0.0 0.76 10.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAK67219.1 - 0.064 12.6 0.0 3.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region cobW PF02492.19 GAK67219.1 - 0.065 12.8 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 GAK67219.1 - 0.086 12.2 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 GAK67219.1 - 0.19 10.9 0.3 0.3 10.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SPT_ssu-like PF11779.8 GAK67220.1 - 0.0056 16.3 0.7 0.0076 15.8 0.7 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like START PF01852.19 GAK67221.1 - 1e-20 74.0 0.2 1.4e-08 34.4 0.2 3.6 3 0 0 3 3 3 3 START domain Coatamer_beta_C PF07718.12 GAK67221.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta C-terminal region DUF3405 PF11885.8 GAK67222.1 - 1.8e-81 274.3 6.5 1.1e-51 176.0 0.5 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3405) Vezatin PF12632.7 GAK67224.1 - 1.6e-19 70.3 0.1 5.1e-13 49.0 0.1 3.5 3 0 0 3 3 3 3 Mysoin-binding motif of peroxisomes Ribosomal_L21p PF00829.21 GAK67225.1 - 2.5e-22 79.0 2.5 5.1e-12 45.9 0.8 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 GAK67225.1 - 0.04 14.0 0.5 0.13 12.4 0.2 1.9 2 1 0 2 2 2 0 UvrA interaction domain ATP-synt_ab PF00006.25 GAK67226.1 - 2.3e-72 243.1 0.0 3.4e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAK67226.1 - 1.2e-38 132.3 0.0 2.2e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 GAK67226.1 - 8.9e-20 71.0 1.9 2.3e-19 69.7 1.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 GAK67226.1 - 0.06 13.5 0.4 0.16 12.1 0.4 1.7 1 1 0 1 1 1 0 HAS barrel domain Dynamin_M PF01031.20 GAK67227.1 - 9.2e-110 366.3 0.0 1.8e-109 365.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GAK67227.1 - 1.9e-55 187.5 0.0 4.7e-55 186.2 0.0 1.7 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 GAK67227.1 - 9e-30 102.7 1.4 1.4e-29 102.1 0.5 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAK67227.1 - 7.3e-05 22.8 0.5 0.0022 18.1 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAK67227.1 - 0.053 12.8 0.1 3.9 6.7 0.0 2.5 2 0 0 2 2 2 0 AIG1 family TipAS PF07739.13 GAK67227.1 - 0.085 13.4 0.2 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain AATase PF07247.12 GAK67228.1 - 1.6e-07 30.3 0.0 2.9e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 GAK67228.1 - 0.064 11.9 0.0 1.1 7.8 0.0 2.5 3 0 0 3 3 3 0 Condensation domain GST_C_2 PF13410.6 GAK67228.1 - 0.37 10.8 2.2 9.9 6.3 0.7 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Sds3 PF08598.11 GAK67229.1 - 4.9e-33 115.0 1.4 4.9e-33 115.0 1.4 1.8 2 0 0 2 2 2 1 Sds3-like Flavodoxin_1 PF00258.25 GAK67230.1 - 1.7e-30 106.1 0.0 2.9e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 GAK67230.1 - 9.7e-24 84.2 0.0 2.9e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAK67230.1 - 8.1e-12 45.7 0.0 1.4e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 GAK67230.1 - 0.0061 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 GAK67230.1 - 0.04 13.6 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain HTH_43 PF09904.9 GAK67230.1 - 0.082 12.9 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DUF1752 PF08550.10 GAK67232.1 - 1.2e-12 47.4 3.2 2.8e-12 46.2 3.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TrbM PF07424.11 GAK67232.1 - 0.024 14.6 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 TrbM Tri3 PF07428.11 GAK67233.1 - 0.16 10.9 0.0 0.51 9.2 0.0 1.7 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 Cellulase PF00150.18 GAK67234.1 - 9.8e-08 31.7 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPPK_C PF12555.8 GAK67234.1 - 0.064 13.3 5.6 0.025 14.6 1.9 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Zw10 PF06248.13 GAK67235.1 - 6.4e-09 34.9 0.0 2.1e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 GAK67235.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Herpes_V23 PF01802.17 GAK67235.1 - 0.16 11.3 0.8 0.61 9.5 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus VP23 like capsid protein DegV PF02645.16 GAK67236.1 - 0.0018 17.6 1.6 0.0036 16.7 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein, DegV family COG1307 Ntox43 PF15537.6 GAK67236.1 - 0.049 13.7 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Bacterial toxin 43 Ctr PF04145.15 GAK67237.1 - 2.8e-36 125.4 0.7 2.8e-36 125.4 0.7 3.2 4 1 0 4 4 4 1 Ctr copper transporter family VPS9 PF02204.18 GAK67237.1 - 2e-30 105.1 0.2 3.6e-30 104.2 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.16 GAK67237.1 - 1.7e-12 46.8 0.2 3.7e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 CUE domain DUF5601 PF18151.1 GAK67237.1 - 1.6e-10 41.1 0.0 5.3e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) DMA PF03474.14 GAK67237.1 - 0.0087 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif LisH PF08513.11 GAK67238.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 LisH WD40 PF00400.32 GAK67241.1 - 5.3e-13 49.2 1.5 0.2 12.6 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat FF PF01846.19 GAK67242.1 - 4.3e-28 97.2 11.8 3.9e-10 39.7 0.0 5.8 6 0 0 6 6 6 4 FF domain WW PF00397.26 GAK67242.1 - 5e-12 45.7 11.4 3.9e-06 26.8 1.6 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 GAK67242.1 - 0.00049 20.7 1.0 0.0073 17.0 0.1 3.3 2 1 2 4 4 4 1 p190-A and -B Rho GAPs FF domain Creatininase PF02633.14 GAK67242.1 - 0.012 15.1 1.7 0.024 14.1 1.4 1.7 1 1 0 1 1 1 0 Creatinine amidohydrolase LysR_substrate PF03466.20 GAK67242.1 - 0.033 13.6 0.1 0.073 12.4 0.1 1.6 1 0 0 1 1 1 0 LysR substrate binding domain DUF1840 PF08895.11 GAK67242.1 - 0.58 10.5 5.3 1.5 9.1 1.4 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Pex19 PF04614.12 GAK67242.1 - 6.5 6.5 15.2 1.7 8.3 5.0 3.2 2 1 1 3 3 3 0 Pex19 protein family RRM_1 PF00076.22 GAK67243.1 - 2.9e-30 103.9 0.1 1.9e-15 56.4 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK67243.1 - 0.0014 18.7 0.0 0.0096 16.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_9 PF18444.1 GAK67243.1 - 0.0023 17.7 0.0 0.062 13.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 GAK67243.1 - 0.12 12.3 0.0 2.1 8.3 0.0 2.6 3 0 0 3 3 3 0 Occluded RNA-recognition motif HMG_CoA_synt_N PF01154.17 GAK67244.1 - 1.8e-86 288.5 0.1 3.4e-86 287.5 0.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 GAK67244.1 - 9.1e-84 281.4 0.1 1.2e-83 281.0 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 GAK67244.1 - 0.0042 17.2 0.0 0.049 13.8 0.0 2.5 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GAK67244.1 - 0.13 12.1 0.2 0.57 10.1 0.1 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cu-oxidase_3 PF07732.15 GAK67245.1 - 4.1e-34 117.2 0.2 9.4e-34 116.0 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAK67245.1 - 1.5e-30 105.7 2.8 3.5e-24 85.1 0.2 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 GAK67245.1 - 3.9e-16 59.6 0.0 5.2e-12 46.2 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Amidase PF01425.21 GAK67246.1 - 5.1e-99 332.3 0.0 1.6e-98 330.7 0.0 1.7 1 1 0 1 1 1 1 Amidase Pkinase PF00069.25 GAK67247.1 - 5.3e-42 144.0 0.0 8.4e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67247.1 - 8.3e-15 54.8 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GAK67247.1 - 0.00018 21.2 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 GAK67247.1 - 0.11 12.1 0.4 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase TPR_1 PF00515.28 GAK67248.1 - 3.1e-24 83.7 0.2 8.7e-09 34.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAK67248.1 - 1.3e-19 69.5 1.8 6.6e-07 28.9 0.4 3.4 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.17 GAK67248.1 - 4.8e-18 63.7 0.1 6.9e-07 28.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAK67248.1 - 5.6e-16 57.4 0.3 7.6e-06 25.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 GAK67248.1 - 1.1e-13 51.5 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase TPR_14 PF13428.6 GAK67248.1 - 1.9e-11 43.8 0.1 4.3e-05 24.0 0.0 4.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAK67248.1 - 3.3e-10 40.3 0.3 1.6e-06 28.6 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAK67248.1 - 2.2e-09 37.1 0.0 0.00016 21.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAK67248.1 - 1.1e-07 31.3 0.0 0.0002 21.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAK67248.1 - 3.7e-07 30.3 0.2 0.053 13.8 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 GAK67248.1 - 7.7e-06 26.4 0.0 0.00064 20.2 0.0 2.5 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 GAK67248.1 - 9.4e-06 26.2 1.8 0.00064 20.3 0.2 4.1 4 1 1 5 5 3 2 Tetratricopeptide repeat SGTA_dimer PF16546.5 GAK67248.1 - 9.1e-05 22.2 0.1 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_10 PF13374.6 GAK67248.1 - 0.00018 21.3 0.1 0.033 14.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAK67248.1 - 0.00065 20.2 1.4 6.2 7.7 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK67248.1 - 0.00065 19.8 0.0 0.15 12.3 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAK67248.1 - 0.0057 15.9 2.0 0.011 15.0 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.11 GAK67248.1 - 0.32 10.8 6.8 0.22 11.3 3.8 2.2 2 0 0 2 2 2 0 XPC-binding domain STI1 PF17830.1 GAK67248.1 - 0.32 11.0 14.2 0.22 11.5 7.9 2.6 2 0 0 2 2 2 0 STI1 domain MIT PF04212.18 GAK67248.1 - 0.41 10.8 6.8 4.4 7.4 0.0 3.0 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain RNase_H2_suC PF08615.11 GAK67249.1 - 3.8e-14 53.1 0.0 1e-13 51.7 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SOG2 PF10428.9 GAK67249.1 - 0.033 13.4 3.8 0.034 13.4 3.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDC45 PF02724.14 GAK67249.1 - 0.083 11.2 2.3 0.099 10.9 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 GAK67249.1 - 0.43 10.0 12.0 0.066 12.6 8.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SAPS PF04499.15 GAK67249.1 - 2.2 7.0 5.8 2.6 6.7 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 GAK67249.1 - 3.2 6.6 6.0 4.1 6.3 6.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAK67249.1 - 3.2 6.4 8.9 4.8 5.8 8.9 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GAK67249.1 - 3.9 6.2 6.6 5.5 5.7 6.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 GAK67249.1 - 4.3 5.4 7.3 4.9 5.1 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HSP70 PF00012.20 GAK67250.1 - 1.1e-73 248.4 0.0 1.7e-73 247.8 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAK67250.1 - 1e-06 27.9 0.3 3.4e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 GAK67250.1 - 0.0032 16.8 0.4 0.012 14.9 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DDR PF08841.10 GAK67250.1 - 0.015 14.3 1.1 0.055 12.5 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Actin PF00022.19 GAK67250.1 - 0.024 13.2 0.0 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Actin PilM_2 PF11104.8 GAK67250.1 - 0.03 13.4 0.0 0.67 8.9 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; MBOAT PF03062.19 GAK67252.1 - 2.9e-36 125.6 17.0 2.9e-36 125.6 17.0 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAK67252.1 - 0.00074 19.7 3.0 0.0025 18.0 3.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_23 PF13489.6 GAK67253.1 - 6e-16 58.7 0.0 7.5e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK67253.1 - 6.5e-15 55.5 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK67253.1 - 5e-14 52.8 0.1 8.4e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK67253.1 - 1.4e-13 51.4 0.1 2.2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK67253.1 - 1.9e-11 44.0 0.0 3.5e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAK67253.1 - 7.2e-06 25.8 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 GAK67253.1 - 3e-05 23.5 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAK67253.1 - 3e-05 23.6 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAK67253.1 - 7.9e-05 22.2 0.1 0.00015 21.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 GAK67253.1 - 0.00027 20.0 0.0 0.00037 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.20 GAK67253.1 - 0.00029 20.0 0.0 0.00039 19.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.11 GAK67253.1 - 0.0027 16.8 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.19 GAK67253.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 GAK67253.1 - 0.019 14.4 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase NodS PF05401.11 GAK67253.1 - 0.023 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.12 GAK67253.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase TehB PF03848.14 GAK67253.1 - 0.099 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPR_12 PF13424.6 GAK67254.1 - 0.11 12.8 2.4 1 9.7 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.20 GAK67255.1 - 4.1e-26 91.0 0.1 1.5e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 GAK67255.1 - 1.1e-06 29.1 0.3 8.1e-06 26.3 0.1 2.7 1 1 1 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAK67255.1 - 0.00036 20.0 0.0 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GAK67255.1 - 0.0025 18.0 0.0 0.0098 16.1 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 GAK67255.1 - 0.0034 17.7 0.0 0.03 14.7 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAK67255.1 - 0.061 13.1 0.1 0.061 13.1 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin Serglycin PF04360.12 GAK67255.1 - 0.31 11.0 4.9 0.64 10.0 4.9 1.5 1 0 0 1 1 1 0 Serglycin DUF1542 PF07564.11 GAK67255.1 - 5.2 7.3 15.5 13 6.0 6.2 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF4451 PF14616.6 GAK67256.1 - 3.9e-18 65.8 1.6 1e-17 64.5 1.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) fn1 PF00039.18 GAK67257.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Fibronectin type I domain Lactamase_B_2 PF12706.7 GAK67260.1 - 6.9e-32 110.6 0.6 1.8e-31 109.2 0.6 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAK67260.1 - 3.9e-13 49.6 0.0 1.2e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAK67260.1 - 0.002 18.2 0.0 0.035 14.1 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Tad_C PF09977.9 GAK67260.1 - 5.6 8.3 7.6 14 6.9 0.7 3.2 3 0 0 3 3 3 0 Putative Tad-like Flp pilus-assembly Prenyltrans PF00432.21 GAK67261.1 - 2.8e-30 103.7 9.8 4.3e-07 29.5 0.0 6.3 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GAK67261.1 - 0.0026 16.9 0.0 1.9 7.5 0.0 2.5 1 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain Amidohydro_3 PF07969.11 GAK67262.1 - 1.1e-10 41.6 10.9 9.1e-05 22.1 0.6 3.8 4 0 0 4 4 4 3 Amidohydrolase family Amidohydro_1 PF01979.20 GAK67262.1 - 1.6e-08 34.3 0.3 0.00025 20.5 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family UNC-93 PF05978.16 GAK67263.1 - 4e-12 46.1 10.6 9.5e-12 44.9 9.0 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 GAK67263.1 - 1.2e-10 40.9 35.2 1.2e-10 40.9 35.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-CCCH PF00642.24 GAK67264.1 - 3e-13 49.3 27.8 2e-06 27.5 2.5 4.7 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK67264.1 - 1.5e-07 31.2 28.2 0.029 14.4 4.3 4.6 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 GAK67264.1 - 0.016 15.9 18.2 0.026 15.2 0.2 4.8 3 1 2 5 5 5 0 Torus domain zf-CCCH_4 PF18044.1 GAK67264.1 - 0.025 14.4 2.1 0.025 14.4 2.1 5.0 5 0 0 5 5 5 0 CCCH-type zinc finger DUF2235 PF09994.9 GAK67265.1 - 1e-66 225.2 0.0 1.1e-65 221.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1917 PF08939.10 GAK67266.1 - 0.00021 21.3 0.0 0.00021 21.3 0.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) CRT-like PF08627.10 GAK67267.1 - 0.039 12.9 1.9 0.045 12.7 1.9 1.1 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like RhoGAP PF00620.27 GAK67268.1 - 5.8e-37 126.9 0.1 1.2e-36 125.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 GAK67268.1 - 4.8e-28 97.2 28.3 5e-11 42.7 3.1 4.8 4 0 0 4 4 4 4 LIM domain SH3_9 PF14604.6 GAK67269.1 - 2.3e-27 94.6 1.5 7.7e-14 51.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAK67269.1 - 9.2e-24 82.8 2.0 1e-12 47.4 0.1 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 GAK67269.1 - 5.8e-21 74.5 0.0 1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 GAK67269.1 - 2.5e-16 59.1 0.1 1.2e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain His_Phos_1 PF00300.22 GAK67270.1 - 1.8e-37 129.0 0.0 2.1e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_4 PF13637.6 GAK67271.1 - 3e-09 37.2 1.3 0.00099 19.6 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK67271.1 - 1.2e-07 32.2 1.5 0.017 15.7 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAK67271.1 - 4e-06 26.7 1.9 0.068 13.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 GAK67271.1 - 1.6e-05 24.7 0.3 0.00021 21.1 0.3 2.2 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 GAK67271.1 - 5.5e-05 23.4 6.5 0.061 13.7 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 GAK67271.1 - 0.0007 19.9 8.8 0.55 10.8 0.6 4.4 4 0 0 4 4 4 2 Ankyrin repeat NYD-SP28 PF14772.6 GAK67271.1 - 0.11 12.5 4.9 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Sperm tail DUF4407 PF14362.6 GAK67271.1 - 0.88 8.9 14.4 0.2 11.0 10.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 GAK67271.1 - 1.7 7.2 6.6 2.5 6.6 6.6 1.1 1 0 0 1 1 1 0 AAA domain MbeD_MobD PF04899.12 GAK67271.1 - 2.1 8.5 4.3 1.2 9.3 0.6 2.4 2 0 0 2 2 2 0 MbeD/MobD like SH3_9 PF14604.6 GAK67272.1 - 3.5e-38 129.2 13.5 9.2e-14 51.0 0.2 4.7 4 1 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 GAK67272.1 - 2.3e-37 126.3 9.1 6.6e-15 54.4 0.2 4.7 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 GAK67272.1 - 1.6e-31 108.0 0.0 2.9e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 GAK67272.1 - 4.1e-25 87.2 0.0 1.3e-07 31.2 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 GAK67272.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 GAK67272.1 - 0.00017 21.8 2.4 0.007 16.6 0.2 2.8 3 0 0 3 3 3 1 Bacterial SH3 domain SH3_10 PF17902.1 GAK67272.1 - 0.0072 16.4 0.1 0.11 12.6 0.0 2.9 3 0 0 3 3 3 1 SH3 domain Rtf2 PF04641.12 GAK67273.1 - 6.9e-72 242.0 1.3 7.7e-72 241.8 1.3 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 GAK67273.1 - 0.00036 20.3 2.1 0.0026 17.6 2.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 GAK67273.1 - 0.0014 18.4 0.7 0.1 12.5 0.0 2.9 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 GAK67273.1 - 0.0029 17.4 1.4 0.0054 16.5 1.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAK67273.1 - 0.0033 17.5 3.4 0.0043 17.2 1.7 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-NOSIP PF15906.5 GAK67273.1 - 0.03 14.4 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 GAK67273.1 - 0.034 14.0 2.5 0.059 13.3 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK67273.1 - 0.12 12.4 2.7 0.21 11.6 2.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 GAK67273.1 - 0.16 11.8 2.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-MIZ PF02891.20 GAK67273.1 - 0.19 11.5 2.1 0.61 9.9 1.3 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF2072 PF09845.9 GAK67273.1 - 0.62 10.3 4.9 1.3 9.3 4.9 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein RR_TM4-6 PF06459.12 GAK67273.1 - 0.79 9.5 6.7 1.2 8.9 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SHS2_Rpb7-N PF03876.17 GAK67274.1 - 1.1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 GAK67274.1 - 3.1e-12 46.7 0.1 5.7e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 GAK67274.1 - 0.05 13.8 0.1 0.08 13.2 0.1 1.4 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Ribonuc_P_40 PF08584.11 GAK67275.1 - 1.6e-29 103.1 0.0 5e-29 101.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit zf-RING_2 PF13639.6 GAK67276.1 - 2.5e-10 40.5 1.2 4.5e-10 39.7 1.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAK67276.1 - 9.4e-09 34.9 0.4 1.8e-08 34.0 0.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAK67276.1 - 6.6e-07 29.1 0.6 1.2e-06 28.3 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK67276.1 - 7.7e-07 29.0 0.8 1.6e-06 28.0 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAK67276.1 - 1.6e-06 28.0 0.7 2.8e-06 27.2 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAK67276.1 - 1.2e-05 25.5 1.0 1.2e-05 25.5 1.0 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 GAK67276.1 - 0.0013 18.9 0.9 0.0027 17.8 0.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAK67276.1 - 0.0021 17.6 0.9 0.0052 16.4 0.2 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 GAK67276.1 - 0.0022 17.8 5.2 0.02 14.7 5.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK67276.1 - 0.0024 17.7 0.4 0.0046 16.8 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK67276.1 - 0.065 13.1 1.1 0.16 11.9 1.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAK67276.1 - 0.19 11.8 0.2 0.45 10.6 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger KORA PF16509.5 GAK67276.1 - 0.36 11.2 3.0 0.18 12.1 0.4 1.8 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Fib_alpha PF08702.10 GAK67276.1 - 4.1 7.6 11.6 5.6 7.1 10.1 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SYS1 PF09801.9 GAK67277.1 - 5.7e-23 81.7 6.9 5e-17 62.4 3.7 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network PIRT PF15099.6 GAK67278.1 - 0.15 11.6 0.2 0.36 10.4 0.2 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family FMO-like PF00743.19 GAK67279.1 - 1.5e-34 119.3 0.0 7.1e-12 44.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAK67279.1 - 3.6e-10 39.6 0.0 0.00012 21.5 0.0 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAK67279.1 - 3.3e-08 33.1 0.0 3.3e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAK67279.1 - 1.9e-06 27.2 0.0 0.054 12.6 0.0 4.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAK67279.1 - 6.3e-06 26.3 0.1 0.00018 21.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAK67279.1 - 3.1e-05 24.0 0.0 0.00017 21.6 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAK67279.1 - 0.0028 18.2 0.3 0.53 10.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAK67279.1 - 0.012 15.7 0.2 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 GAK67279.1 - 0.015 14.6 0.0 0.71 9.1 0.0 2.4 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 GAK67279.1 - 0.035 14.5 0.1 2.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 GAK67280.1 - 2.1e-11 43.9 0.0 5.7e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAK67280.1 - 0.0016 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAK67280.1 - 0.0039 16.5 0.0 0.052 12.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK67280.1 - 0.0039 15.9 0.1 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAK67280.1 - 0.0052 16.4 0.1 0.055 13.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAK67280.1 - 0.079 12.9 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAK67280.1 - 0.092 12.0 0.1 2.9 7.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAK67280.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Terpene_synth_C PF03936.16 GAK67280.1 - 3.3 7.0 7.5 0.071 12.5 0.8 1.5 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain SET PF00856.28 GAK67282.1 - 5.2e-18 66.0 0.1 1.9e-17 64.2 0.0 2.0 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 GAK67282.1 - 4.4e-12 46.6 1.7 4.4e-12 46.6 1.7 2.3 2 0 0 2 2 2 1 Pre-SET motif CSRNP_N PF16019.5 GAK67282.1 - 0.021 14.8 2.0 0.021 14.8 2.0 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Sec7 PF01369.20 GAK67283.1 - 1.6e-33 115.9 0.0 2.4e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 GAK67283.1 - 0.24 11.4 0.0 0.42 10.6 0.0 1.3 1 0 0 1 1 1 0 PH domain DUF4449 PF14613.6 GAK67284.1 - 3.1e-38 131.4 0.4 3.1e-38 131.4 0.4 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) TPR_6 PF13174.6 GAK67284.1 - 0.035 14.8 0.7 18 6.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sortilin-Vps10 PF15902.5 GAK67285.1 - 5.9e-286 948.2 3.5 8.9e-150 499.4 0.1 2.3 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 GAK67285.1 - 3.5e-91 304.1 15.0 1.2e-48 165.7 6.4 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 GAK67285.1 - 2.2e-09 35.9 42.5 1.8 8.9 0.0 12.0 11 0 0 11 11 11 5 BNR/Asp-box repeat Fe_dep_repr_C PF02742.15 GAK67285.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain BNR_2 PF13088.6 GAK67285.1 - 0.033 13.5 8.1 0.39 10.0 0.1 5.0 5 1 1 6 6 6 0 BNR repeat-like domain PSII_BNR PF14870.6 GAK67285.1 - 0.037 13.3 4.8 3 7.0 0.0 4.2 4 1 0 4 4 4 0 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 GAK67285.1 - 0.14 12.3 11.3 1.1 9.5 0.3 5.1 4 0 0 4 4 4 0 BNR-Asp box repeat F5_F8_type_C PF00754.25 GAK67285.1 - 0.15 12.2 5.9 2.9 8.0 0.0 5.6 7 1 1 8 8 8 0 F5/8 type C domain DUF4185 PF13810.6 GAK67285.1 - 5.1 6.2 9.6 5 6.3 0.2 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4185) SRF-TF PF00319.18 GAK67286.1 - 3.4e-21 74.4 0.0 5.5e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MS_channel PF00924.18 GAK67288.1 - 7.6e-22 77.9 1.4 1.3e-21 77.2 1.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 GAK67288.1 - 3.2e-06 26.3 0.1 6.6e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAK67288.1 - 7.4e-05 22.4 0.0 0.0002 21.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAK67288.1 - 0.00059 20.2 0.2 0.0015 19.0 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAK67288.1 - 0.0007 19.0 0.1 0.0016 17.8 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GAK67288.1 - 0.039 13.8 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair PBP1_TM PF14812.6 GAK67288.1 - 0.077 13.4 0.1 0.31 11.4 0.1 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VIT1 PF01988.19 GAK67288.1 - 2.8 7.8 8.9 4.8 7.0 3.5 2.7 2 1 0 2 2 2 0 VIT family DUF1576 PF07613.11 GAK67288.1 - 3.2 7.2 9.4 0.091 12.3 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1576) Tubulin PF00091.25 GAK67289.1 - 6e-57 193.0 0.0 9.3e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAK67289.1 - 4e-37 127.2 0.0 6.2e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAK67289.1 - 0.0009 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 GAK67289.1 - 0.0011 18.3 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Plug_translocon PF10559.9 GAK67290.1 - 0.03 14.1 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p MFS_1 PF07690.16 GAK67292.1 - 2.1e-37 128.9 51.6 2.1e-37 128.9 51.6 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAK67292.1 - 7.4e-10 37.9 24.7 1.1e-09 37.3 24.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAK67292.1 - 4e-09 35.9 9.5 4e-09 35.9 9.5 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter STT3 PF02516.14 GAK67301.1 - 3.6e-144 481.3 30.0 1.5e-137 459.5 27.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pep3_Vps18 PF05131.14 GAK67302.1 - 8e-50 168.5 0.0 2.2e-49 167.1 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 GAK67302.1 - 8.2e-13 48.5 2.0 5e-07 29.7 0.0 3.1 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 GAK67302.1 - 0.00042 20.7 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.9 GAK67302.1 - 0.0087 16.3 0.3 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 GAK67302.1 - 0.012 15.6 2.3 0.012 15.6 2.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain DUF4249 PF14054.6 GAK67302.1 - 0.027 14.1 0.3 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) zf-RING_11 PF17123.5 GAK67302.1 - 0.082 12.7 5.3 0.17 11.7 5.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAK67302.1 - 0.15 11.7 1.7 0.28 10.8 1.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 GAK67302.1 - 0.52 10.7 6.0 0.2 12.0 2.6 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 GAK67302.1 - 5.7 6.9 9.8 0.22 11.4 3.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MTP18 PF10558.9 GAK67303.1 - 7.6e-69 231.1 1.7 1.4e-68 230.2 1.7 1.4 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Glyco_hydro_18 PF00704.28 GAK67304.1 - 5.2e-07 29.7 0.0 8.9e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 GAK67305.1 - 4.7e-72 242.5 0.0 5.3e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67305.1 - 2e-31 109.3 0.0 2.4e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK67305.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAK67305.1 - 0.00053 19.0 0.0 0.0029 16.6 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAK67305.1 - 0.0016 18.4 0.1 0.0034 17.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAK67305.1 - 0.0065 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Peptidase_S9_N PF02897.15 GAK67306.1 - 2.5e-82 276.9 3.7 3.5e-82 276.4 3.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 GAK67306.1 - 2.2e-50 171.1 0.1 3.4e-50 170.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SAD_SRA PF02182.17 GAK67307.1 - 3.2e-55 186.1 0.1 8e-55 184.8 0.0 1.7 2 0 0 2 2 2 1 SAD/SRA domain Trypan_PARP PF05887.11 GAK67307.1 - 0.0068 16.4 5.0 0.0068 16.4 5.0 2.6 3 0 0 3 3 3 2 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.6 GAK67307.1 - 0.061 13.7 10.2 1.7 9.1 0.1 3.0 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vps5 PF09325.10 GAK67308.1 - 7.4e-68 228.6 5.7 7.4e-68 228.6 5.7 3.2 3 1 1 4 4 4 1 Vps5 C terminal like RmlD_sub_bind PF04321.17 GAK67308.1 - 1.9e-53 181.5 0.1 6e-53 179.8 0.1 1.9 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAK67308.1 - 7.3e-24 84.5 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.24 GAK67308.1 - 1.3e-22 79.9 0.0 2.7e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 PX domain GDP_Man_Dehyd PF16363.5 GAK67308.1 - 4.8e-10 39.3 0.0 4.8e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAK67308.1 - 8.4e-08 31.7 0.2 3.6e-06 26.3 0.2 3.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAK67308.1 - 0.001 18.3 0.0 0.001 18.3 0.0 2.8 3 1 0 3 3 3 1 Male sterility protein DIL PF01843.19 GAK67308.1 - 0.024 14.9 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 DIL domain DUF572 PF04502.13 GAK67308.1 - 1.1 8.9 29.9 0.03 13.9 11.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) HAD_2 PF13419.6 GAK67309.1 - 1.6e-17 64.1 0.0 1.8e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAK67309.1 - 5.8e-12 46.4 0.1 9.4e-11 42.4 0.0 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAK67309.1 - 0.00099 19.6 0.0 0.002 18.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAK67309.1 - 0.019 15.0 0.0 0.71 10.0 0.0 3.1 3 1 0 3 3 3 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 GAK67309.1 - 0.095 12.8 0.0 21 5.3 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PPP5 PF08321.12 GAK67310.1 - 1.2e-26 92.9 0.0 2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 GAK67310.1 - 2.1e-26 93.7 0.0 1.1e-25 91.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 GAK67310.1 - 1e-11 44.1 3.2 0.00025 20.7 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAK67310.1 - 2.4e-08 33.5 3.1 0.024 14.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAK67310.1 - 9.4e-07 28.4 0.7 0.00066 19.3 0.2 2.8 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 GAK67310.1 - 0.00032 20.9 0.4 2.2 8.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAK67310.1 - 0.00057 20.5 0.3 0.0017 19.0 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAK67310.1 - 0.016 15.4 2.6 7.3 7.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 GAK67310.1 - 4.2 6.9 6.0 23 4.5 0.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HMG_box_5 PF14887.6 GAK67311.1 - 0.05 13.6 0.2 0.14 12.1 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 BAR PF03114.18 GAK67312.1 - 5e-49 167.1 1.2 6.6e-49 166.7 1.2 1.1 1 0 0 1 1 1 1 BAR domain Jnk-SapK_ap_N PF09744.9 GAK67312.1 - 0.0013 19.0 1.2 0.24 11.6 1.4 2.5 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 AAA_13 PF13166.6 GAK67312.1 - 0.004 15.9 1.6 0.005 15.5 1.6 1.1 1 0 0 1 1 1 1 AAA domain Arfaptin PF06456.13 GAK67312.1 - 0.0046 16.6 2.8 0.0097 15.5 2.8 1.8 1 1 0 1 1 1 1 Arfaptin-like domain Sigma70_ner PF04546.13 GAK67312.1 - 0.029 14.3 0.2 0.029 14.3 0.2 2.6 1 1 2 3 3 3 0 Sigma-70, non-essential region Laminin_I PF06008.14 GAK67312.1 - 0.03 14.0 0.6 0.03 14.0 0.6 1.7 2 0 0 2 2 2 0 Laminin Domain I CdvA PF18822.1 GAK67312.1 - 0.044 13.6 1.8 0.11 12.3 0.2 2.5 3 0 0 3 3 3 0 CdvA-like coiled-coil domain BLOC1_2 PF10046.9 GAK67312.1 - 0.047 14.0 0.5 0.27 11.5 0.5 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 GAK67312.1 - 0.067 12.4 0.5 0.13 11.5 0.1 1.6 1 1 1 2 2 2 0 TMPIT-like protein HD_3 PF13023.6 GAK67312.1 - 0.077 12.9 0.4 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 HD domain Sec34 PF04136.15 GAK67312.1 - 0.08 12.8 0.4 0.22 11.4 0.2 1.9 2 0 0 2 2 2 0 Sec34-like family BAR_3 PF16746.5 GAK67312.1 - 0.086 12.5 1.4 0.38 10.4 1.1 2.2 1 1 1 2 2 2 0 BAR domain of APPL family IFT57 PF10498.9 GAK67312.1 - 0.14 11.1 1.9 0.12 11.4 0.6 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 GAK67312.1 - 0.17 11.3 3.6 0.059 12.8 1.0 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF948 PF06103.11 GAK67312.1 - 0.18 12.0 1.6 1.2 9.4 0.1 2.9 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 GAK67312.1 - 0.3 10.9 2.8 0.31 10.8 0.8 2.1 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.6 GAK67312.1 - 0.93 8.8 4.6 0.5 9.7 0.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 GAK67312.1 - 3.1 8.1 7.0 2.8 8.2 1.3 2.5 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Snf7 PF03357.21 GAK67313.1 - 2.2e-49 167.4 14.3 2.5e-49 167.2 14.3 1.0 1 0 0 1 1 1 1 Snf7 NuA4 PF09340.10 GAK67313.1 - 0.0032 17.3 0.8 0.0081 16.0 0.8 1.7 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Phasin PF05597.11 GAK67313.1 - 0.02 14.9 1.6 0.02 14.9 1.6 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Soyouz_module PF14313.6 GAK67313.1 - 0.035 13.9 0.1 12 5.8 0.0 2.8 3 0 0 3 3 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) FlxA PF14282.6 GAK67313.1 - 0.12 12.4 11.7 0.026 14.5 6.7 2.2 1 1 1 2 2 2 0 FlxA-like protein CTNNBL PF08216.11 GAK67313.1 - 0.14 12.3 3.4 0.21 11.8 2.2 1.9 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Macoilin PF09726.9 GAK67313.1 - 0.15 10.6 7.0 0.18 10.4 7.0 1.0 1 0 0 1 1 1 0 Macoilin family FlaC_arch PF05377.11 GAK67313.1 - 0.17 12.3 5.9 6.8 7.2 0.0 3.7 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) DUF848 PF05852.11 GAK67313.1 - 0.2 11.8 7.5 0.3 11.2 6.8 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PEP-utilisers_N PF05524.13 GAK67313.1 - 0.22 11.7 11.1 0.062 13.5 3.1 2.6 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal V_ATPase_I PF01496.19 GAK67313.1 - 0.24 9.3 5.8 0.29 9.0 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.17 GAK67313.1 - 0.27 11.1 10.7 7.6 6.5 1.2 3.5 4 0 0 4 4 4 0 Prefoldin subunit Prefoldin_2 PF01920.20 GAK67313.1 - 0.56 10.2 13.9 3.9 7.5 0.0 3.4 2 1 0 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.12 GAK67313.1 - 1 9.9 7.4 6.3 7.3 1.8 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HalX PF08663.10 GAK67313.1 - 1.3 9.4 11.1 16 5.9 2.7 3.5 3 1 0 3 3 3 0 HalX domain BST2 PF16716.5 GAK67313.1 - 2.7 8.6 12.0 14 6.4 8.4 3.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 ABC_tran_CTD PF16326.5 GAK67313.1 - 8.9 6.7 15.0 50 4.2 3.7 3.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 GAK67313.1 - 9.6 6.6 18.6 18 5.7 14.5 2.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ssl1 PF04056.14 GAK67314.1 - 8.4e-68 228.0 0.0 1.3e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 GAK67314.1 - 2.2e-16 59.8 9.9 2.2e-16 59.8 9.9 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 GAK67314.1 - 1.1e-11 45.3 0.1 3.5e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 GAK67314.1 - 0.0035 18.0 5.7 0.0035 18.0 5.7 2.5 1 1 1 2 2 2 1 zinc-ribbon family Tfb4 PF03850.14 GAK67314.1 - 5.3 6.5 6.4 49 3.3 5.5 2.5 2 1 0 3 3 3 0 Transcription factor Tfb4 IBR PF01485.21 GAK67314.1 - 7.1 6.9 18.2 0.29 11.4 9.6 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 GAK67314.1 - 9.8 6.3 22.6 1.8e+04 -4.7 22.6 2.9 1 1 0 1 1 1 0 Double zinc ribbon SWI-SNF_Ssr4 PF08549.10 GAK67315.1 - 5.9e-06 25.2 0.3 5.9e-06 25.2 0.3 3.3 2 1 0 3 3 3 1 Fungal domain of unknown function (DUF1750) Collagen PF01391.18 GAK67315.1 - 2e-05 24.2 23.4 2e-05 24.2 23.4 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Nop53 PF07767.11 GAK67316.1 - 4.8e-106 355.5 22.4 5.9e-106 355.2 22.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) MurB_C PF02873.16 GAK67316.1 - 0.092 12.8 0.5 0.22 11.6 0.5 1.6 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DUF3106 PF11304.8 GAK67316.1 - 0.82 10.2 19.9 1.1 9.8 11.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Ank_2 PF12796.7 GAK67317.1 - 3e-17 63.0 0.3 5e-15 55.9 0.9 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK67317.1 - 3.4e-15 56.2 4.1 2.9e-11 43.6 0.8 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAK67317.1 - 8.6e-13 47.2 0.5 5e-05 23.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAK67317.1 - 3.3e-12 46.3 4.2 7.8e-05 22.9 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAK67317.1 - 3.9e-11 43.0 3.0 0.00011 22.4 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Angiomotin_C PF12240.8 GAK67317.1 - 0.033 13.7 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Angiomotin C terminal Mt_ATP-synt_B PF05405.14 GAK67318.1 - 1.7e-39 135.0 12.8 1e-26 93.5 9.6 2.1 2 0 0 2 2 2 2 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FMN_bind PF04205.14 GAK67318.1 - 0.062 13.9 0.3 0.19 12.3 0.3 1.8 1 0 0 1 1 1 0 FMN-binding domain Cauli_DNA-bind PF03310.13 GAK67318.1 - 0.18 11.8 3.5 0.19 11.8 1.9 1.8 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein SLATT_1 PF18181.1 GAK67318.1 - 1.7 8.6 8.1 0.34 10.9 3.6 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 BCDHK_Adom3 PF10436.9 GAK67320.1 - 9.9e-67 223.8 0.0 1.4e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAK67320.1 - 3.7e-13 50.0 0.0 7.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAK67320.1 - 4.9e-05 23.2 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSF_DNA-bind PF00447.17 GAK67321.1 - 5.6e-31 107.0 1.3 9.1e-31 106.3 1.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4157 PF13699.6 GAK67321.1 - 0.032 14.5 0.1 0.12 12.7 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) HAP1_N PF04849.13 GAK67321.1 - 0.058 12.6 0.3 0.087 12.0 0.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.12 GAK67321.1 - 0.19 11.8 0.7 0.38 10.8 0.7 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DPPIV_N PF00930.21 GAK67322.1 - 4.7e-75 252.6 0.1 1.1e-74 251.4 0.1 1.6 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAK67322.1 - 4.2e-46 157.1 3.5 6.7e-46 156.4 3.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAK67322.1 - 9.9e-06 25.3 6.1 1.6e-05 24.6 4.1 2.3 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 GAK67322.1 - 1.1e-05 24.3 0.0 0.00073 18.3 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 GAK67322.1 - 1.4e-05 25.8 0.8 1.4e-05 25.8 0.8 3.2 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAK67322.1 - 0.00011 22.0 0.1 0.00021 21.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 GAK67322.1 - 0.0096 15.4 0.5 0.022 14.2 0.5 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GAK67322.1 - 0.049 12.9 0.3 0.27 10.5 0.1 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 GAK67322.1 - 0.08 12.5 0.1 0.23 11.0 0.1 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Glyco_trans_2_3 PF13632.6 GAK67322.1 - 0.085 12.8 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family group 2 BAAT_C PF08840.11 GAK67322.1 - 0.15 12.0 0.0 14 5.5 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.16 GAK67323.1 - 6.4e-23 81.2 34.9 2.2e-17 63.0 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 GAK67323.1 - 2.5 6.2 11.7 0.18 10.0 0.9 3.0 3 1 1 4 4 4 0 BT1 family SLAC1 PF03595.17 GAK67324.1 - 1.1e-80 271.3 55.8 1.3e-80 271.1 55.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1349 PF07081.11 GAK67325.1 - 7.4e-33 113.8 0.0 8.9e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) E1-E2_ATPase PF00122.20 GAK67326.1 - 1e-29 103.3 0.3 2.1e-29 102.4 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 GAK67326.1 - 2.1e-27 95.7 0.0 8.2e-27 93.8 0.0 2.0 1 1 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 GAK67326.1 - 2.8e-18 67.0 0.1 6.6e-10 39.6 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK67326.1 - 4.9e-06 26.1 0.0 8.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAK67326.1 - 2.1e-05 24.5 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) AA_permease PF00324.21 GAK67327.1 - 6.7e-101 338.2 43.3 8.3e-101 337.9 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK67327.1 - 1e-26 93.8 47.7 1.3e-26 93.5 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease RA PF00788.23 GAK67328.1 - 1.6e-13 51.1 0.0 2.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 GAK67328.1 - 3.8e-13 48.8 0.3 3.5e-08 32.9 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SAM_1 PF00536.30 GAK67328.1 - 6.2e-13 49.0 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAK67328.1 - 2.1e-12 46.9 0.0 3.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 GAK67328.1 - 1e-10 41.3 1.1 4.9e-06 26.3 0.1 3.0 2 0 0 2 2 2 2 Variant SH3 domain SAM_4 PF18017.1 GAK67328.1 - 0.21 11.6 0.1 0.53 10.3 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2205 PF10224.9 GAK67329.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Short coiled-coil protein ADH_N PF08240.12 GAK67330.1 - 3.7e-26 91.2 1.5 7.1e-26 90.2 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 GAK67330.1 - 3.5e-09 36.4 0.2 9.9e-09 35.0 0.2 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 GAK67330.1 - 1.5e-07 31.5 0.0 0.00019 21.4 0.0 2.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TF_Zn_Ribbon PF08271.12 GAK67330.1 - 7.1e-05 22.2 0.9 0.00019 20.9 0.9 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding 2-Hacid_dh_C PF02826.19 GAK67330.1 - 0.0081 15.5 0.0 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_Tnp_IS1595 PF12760.7 GAK67330.1 - 0.018 15.0 0.1 0.055 13.5 0.1 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Sacchrp_dh_NADP PF03435.18 GAK67330.1 - 0.023 15.0 0.0 0.065 13.5 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DZR PF12773.7 GAK67330.1 - 0.14 12.2 3.3 0.6 10.2 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 GAK67330.1 - 0.19 11.7 1.4 0.46 10.5 1.4 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF3807 PF12720.7 GAK67330.1 - 0.83 9.9 23.7 0.24 11.6 17.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3807) Cdh1_DBD_1 PF18196.1 GAK67330.1 - 6.9 7.0 6.4 6.3 7.1 2.8 2.4 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 SurE PF01975.17 GAK67332.1 - 2.9e-41 141.4 0.0 3.9e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Cation_ATPase_C PF00689.21 GAK67333.1 - 0.0037 17.0 2.9 0.0061 16.3 2.9 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus EVC2_like PF12297.8 GAK67333.1 - 0.031 13.0 0.1 0.055 12.2 0.1 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein ALMT PF11744.8 GAK67333.1 - 0.32 9.8 2.4 0.57 9.0 2.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Fijivirus_P9-2 PF06837.11 GAK67333.1 - 1.3 8.4 4.1 0.96 8.9 1.9 1.7 1 1 1 2 2 2 0 Fijivirus P9-2 protein HemY_N PF07219.13 GAK67333.1 - 1.9 8.7 11.6 0.2 11.9 0.9 2.5 1 1 1 2 2 2 0 HemY protein N-terminus Sugar_tr PF00083.24 GAK67334.1 - 4.3e-21 75.3 24.9 9.2e-20 70.9 24.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.24 GAK67336.1 - 2.2e-61 208.4 1.7 2.5e-61 208.3 1.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK67336.1 - 5.1e-08 32.5 0.7 0.0016 17.7 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK67336.1 - 7.2e-06 26.5 0.4 0.01 16.4 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK67336.1 - 0.00035 20.7 1.0 0.0013 19.0 0.7 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAK67336.1 - 0.0015 17.7 6.3 0.0069 15.5 6.3 1.9 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 GAK67336.1 - 0.0024 16.8 0.6 0.076 11.9 0.7 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Mqo PF06039.15 GAK67336.1 - 0.0077 14.8 0.2 0.4 9.2 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) GMC_oxred_N PF00732.19 GAK67336.1 - 0.01 15.2 0.5 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 GAK67336.1 - 0.015 15.3 0.4 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAK67336.1 - 0.039 13.2 0.7 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain MCRA PF06100.11 GAK67336.1 - 0.051 12.4 1.8 0.3 9.8 0.0 2.0 2 0 0 2 2 2 0 MCRA family TrkA_N PF02254.18 GAK67336.1 - 0.065 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 GAK67336.1 - 0.085 12.2 3.8 0.27 10.5 3.8 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAK67336.1 - 0.1 11.6 1.8 7.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.6 GAK67336.1 - 0.1 11.7 0.4 2.1 7.4 0.2 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 GAK67336.1 - 0.41 10.3 1.7 0.43 10.2 0.6 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Nup35_RRM PF05172.13 GAK67337.1 - 3.9e-08 33.2 0.0 8.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 GAK67337.1 - 0.032 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Histone PF00125.24 GAK67338.1 - 5.3e-40 136.8 0.0 6.6e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAK67338.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAK67338.1 - 0.095 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein ADIP PF11559.8 GAK67339.1 - 2.3e-27 95.9 8.0 2.3e-27 95.9 8.0 4.7 4 1 1 5 5 5 1 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.11 GAK67339.1 - 0.64 9.9 6.4 11 6.0 0.4 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Dabb PF07876.12 GAK67340.1 - 8.6e-19 68.0 0.2 9.6e-19 67.8 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Putative_PNPOx PF01243.20 GAK67340.1 - 0.16 12.2 0.0 0.8 9.9 0.0 2.0 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase NAD_binding_10 PF13460.6 GAK67341.1 - 1.7e-10 41.1 0.1 1.7e-10 41.1 0.1 1.7 3 0 0 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 GAK67341.1 - 0.00042 19.9 0.1 0.04 13.5 0.0 2.3 2 1 0 2 2 2 2 NmrA-like family MTS PF05175.14 GAK67341.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ABC2_membrane PF01061.24 GAK67342.1 - 1.6e-65 220.4 48.2 1.5e-36 125.8 18.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAK67342.1 - 7e-38 130.2 0.1 1e-18 68.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 GAK67342.1 - 1.9e-21 75.7 5.0 6.6e-20 70.8 0.0 3.4 3 0 0 3 3 3 1 CDR ABC transporter AAA_16 PF13191.6 GAK67342.1 - 1.5e-07 31.9 1.4 0.00066 20.1 0.4 2.8 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 GAK67342.1 - 1.6e-07 31.8 0.0 4e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 GAK67342.1 - 6e-05 23.0 1.5 0.16 11.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAK67342.1 - 6.8e-05 22.5 2.2 0.028 14.1 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 GAK67342.1 - 0.00024 20.7 0.2 0.0033 17.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAK67342.1 - 0.00026 21.5 0.1 0.095 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAK67342.1 - 0.0003 21.1 0.7 0.49 10.7 0.2 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAK67342.1 - 0.001 19.0 1.4 0.0097 15.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAK67342.1 - 0.0081 16.2 2.2 3.4 7.8 0.1 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase SMC_N PF02463.19 GAK67342.1 - 0.019 14.4 0.0 3.6 7.0 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 GAK67342.1 - 0.09 12.9 0.8 0.99 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 GAK67342.1 - 0.15 11.4 0.2 3.4 6.9 0.2 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Rad51 PF08423.11 GAK67342.1 - 0.2 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Rad51 ABC_ATPase PF09818.9 GAK67342.1 - 0.3 9.8 1.7 0.32 9.7 0.4 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 GAK67342.1 - 0.55 10.1 1.8 5.7 6.8 0.5 2.5 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 GAK67342.1 - 0.65 9.3 2.7 1.8 7.9 0.5 2.4 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 GAK67342.1 - 0.91 10.0 5.3 0.36 11.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 GAK67342.1 - 1.3 8.6 3.6 3.2 7.3 0.8 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAK67342.1 - 6.8 6.3 11.0 1.4 8.6 0.1 3.3 4 0 0 4 4 3 0 AAA domain Fungal_trans PF04082.18 GAK67343.1 - 2.2e-17 63.0 0.0 4.2e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 GAK67344.1 - 9.7e-58 195.5 1.6 1.1e-57 195.3 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK67344.1 - 8.8e-43 146.0 2.1 1.2e-42 145.6 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK67344.1 - 2.1e-11 44.0 0.5 3e-11 43.6 0.5 1.2 1 0 0 1 1 1 1 KR domain SBP_bac_11 PF13531.6 GAK67344.1 - 0.037 13.8 0.6 0.092 12.5 0.6 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein S4 PF01479.25 GAK67344.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 S4 domain ox_reductase_C PF08635.10 GAK67345.1 - 5.3e-49 165.5 0.0 7.4e-49 165.0 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 GAK67345.1 - 5e-13 49.9 0.0 8.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAK67345.1 - 4.4e-06 26.7 0.0 9.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4535 PF15054.6 GAK67346.1 - 3.4 7.5 4.7 1.2 8.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) Proteasome PF00227.26 GAK67350.1 - 2e-55 187.2 0.6 3.5e-55 186.5 0.6 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAK67350.1 - 2.9e-13 49.2 0.1 9.6e-13 47.6 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Abhydrolase_6 PF12697.7 GAK67350.1 - 0.00058 20.5 0.0 0.0024 18.5 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GAK67350.1 - 0.00074 19.3 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK67350.1 - 0.018 14.3 0.0 0.064 12.5 0.0 1.9 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAK67350.1 - 0.072 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 GAK67350.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PAP_central PF04928.17 GAK67351.1 - 2.1e-108 361.0 0.0 4.2e-108 360.0 0.0 1.5 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAK67351.1 - 6.6e-57 191.9 0.2 2.3e-56 190.1 0.1 1.9 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAK67351.1 - 3.8e-11 43.1 0.0 1.1e-10 41.6 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 GAK67351.1 - 0.12 12.1 0.2 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Ribosomal_L22 PF00237.19 GAK67352.1 - 9.9e-33 112.5 0.1 2.3e-32 111.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ELFV_dehydrog PF00208.21 GAK67354.1 - 1.4e-55 188.7 0.0 2e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAK67354.1 - 1.4e-21 75.9 0.0 1.6e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Arrestin_N PF00339.29 GAK67355.1 - 0.00032 20.8 0.0 0.0022 18.1 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Abhydrolase_1 PF00561.20 GAK67356.1 - 1.5e-19 70.7 0.1 2.1e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK67356.1 - 2.2e-14 54.6 3.9 2.2e-14 54.6 3.9 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK67356.1 - 2.4e-09 36.8 0.0 4.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 GAK67356.1 - 6.9e-09 35.6 0.3 2.1e-08 34.1 0.3 1.9 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Peptidase_S9 PF00326.21 GAK67356.1 - 2.1e-05 24.1 0.0 0.039 13.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 GAK67356.1 - 0.0001 21.1 0.0 0.00029 19.7 0.0 1.7 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 GAK67356.1 - 0.00011 21.9 0.1 0.00022 21.0 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 GAK67356.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 GAK67356.1 - 0.083 12.8 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Dioxygenase_C PF00775.21 GAK67357.1 - 2e-07 30.6 0.2 3.4e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Dioxygenase DNA_methylase PF00145.17 GAK67358.1 - 4e-48 164.5 0.0 1.1e-47 163.0 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_25 PF13649.6 GAK67358.1 - 0.13 12.9 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ENTH PF01417.20 GAK67359.1 - 3.4e-44 149.9 0.2 4.9e-44 149.4 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAK67359.1 - 6.6e-05 22.0 0.0 9.8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain NB-LRR PF12061.8 GAK67359.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 GRP PF07172.11 GAK67359.1 - 0.25 12.0 14.1 0.56 10.9 14.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family Pinin_SDK_N PF04697.13 GAK67359.1 - 4 8.1 7.9 0.24 12.1 0.8 2.4 2 1 1 3 3 3 0 pinin/SDK conserved region Peptidase_M16 PF00675.20 GAK67360.1 - 8.9e-55 184.8 0.2 2.2e-54 183.5 0.2 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAK67360.1 - 2.5e-39 135.2 0.0 7.7e-37 127.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain WD40 PF00400.32 GAK67361.1 - 0.00012 22.8 0.2 1.1 10.2 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat RR_TM4-6 PF06459.12 GAK67361.1 - 9.1 6.0 7.9 15 5.3 1.7 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EF-hand_6 PF13405.6 GAK67363.1 - 1.9e-09 36.7 0.1 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAK67363.1 - 1.2e-08 35.3 0.0 4.6e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAK67363.1 - 1e-07 31.0 0.1 0.0024 17.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 GAK67363.1 - 6.9e-07 28.5 0.1 0.00097 18.5 0.0 2.7 2 0 0 2 2 2 2 EF hand RRM_1 PF00076.22 GAK67363.1 - 1.6e-06 27.8 0.0 3.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_8 PF13833.6 GAK67363.1 - 5.8e-05 22.9 0.1 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Dioxygenase_C PF00775.21 GAK67364.1 - 0.032 13.7 0.4 0.05 13.0 0.4 1.2 1 0 0 1 1 1 0 Dioxygenase Aconitase PF00330.20 GAK67366.1 - 1.2e-164 548.7 0.1 1.4e-164 548.5 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAK67366.1 - 1.2e-42 145.4 0.0 2.3e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_membrane PF00664.23 GAK67367.1 - 7.6e-108 360.3 25.1 2.2e-60 204.6 14.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK67367.1 - 3.2e-66 222.0 0.0 1.1e-32 113.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAK67367.1 - 5.3e-16 58.7 2.5 4.2e-06 26.4 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK67367.1 - 3.2e-07 30.0 0.2 0.0039 16.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 GAK67367.1 - 6.1e-07 29.5 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAK67367.1 - 1.2e-06 28.5 0.2 0.056 13.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAK67367.1 - 1.7e-06 28.4 0.5 0.18 12.0 0.1 3.5 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 GAK67367.1 - 1.8e-06 27.0 4.1 0.0074 15.1 0.2 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GAK67367.1 - 2.2e-05 24.9 8.1 0.041 14.3 0.4 3.7 2 2 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAK67367.1 - 3.4e-05 23.8 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 GAK67367.1 - 3.6e-05 23.1 0.5 0.14 11.5 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_30 PF13604.6 GAK67367.1 - 5.5e-05 23.0 1.3 0.82 9.3 0.3 4.1 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 GAK67367.1 - 0.00014 22.3 3.2 1.2 9.6 0.3 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAK67367.1 - 0.00035 20.2 0.0 0.12 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GAK67367.1 - 0.0004 19.7 0.0 0.45 9.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_23 PF13476.6 GAK67367.1 - 0.00068 20.2 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAK67367.1 - 0.00086 18.9 0.1 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 GAK67367.1 - 0.0012 18.6 0.0 0.96 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 GAK67367.1 - 0.0021 18.3 3.5 2.3 8.5 0.5 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 GAK67367.1 - 0.003 17.6 0.1 3.4 7.7 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAK67367.1 - 0.0043 17.1 0.0 2.1 8.4 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_18 PF13238.6 GAK67367.1 - 0.0062 17.1 0.0 5.6 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAK67367.1 - 0.0071 16.5 0.0 4.7 7.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAK67367.1 - 0.01 16.1 0.3 2.1 8.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 GAK67367.1 - 0.017 14.9 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 GAK67367.1 - 0.019 14.2 0.0 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 GAK67367.1 - 0.019 14.1 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAK67367.1 - 0.037 14.4 0.3 5.6 7.4 0.0 3.4 4 0 0 4 4 3 0 RNA helicase Rad17 PF03215.15 GAK67367.1 - 0.046 13.6 0.0 0.78 9.6 0.1 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 GAK67367.1 - 0.047 13.8 3.0 8.4 6.4 0.0 3.3 3 1 0 3 3 3 0 Helicase HerA, central domain AAA_17 PF13207.6 GAK67367.1 - 0.089 13.2 0.0 36 4.8 0.0 3.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAK67367.1 - 0.14 11.9 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 GAK67367.1 - 0.18 11.9 1.5 15 5.7 0.0 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase Macoilin PF09726.9 GAK67367.1 - 0.78 8.2 2.4 1.6 7.2 2.4 1.4 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 GAK67367.1 - 4.4 7.0 5.9 11 5.7 5.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Dynamin_N PF00350.23 GAK67368.1 - 6.1e-17 62.2 0.2 8.2e-16 58.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAK67368.1 - 3.1e-11 43.4 0.0 2.2e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAK67368.1 - 2.1e-05 24.2 0.1 0.0061 16.1 0.1 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAK67368.1 - 5.5e-05 23.1 0.5 0.55 10.1 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase TsaE PF02367.17 GAK67368.1 - 0.0036 17.3 0.0 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 GAK67368.1 - 0.01 15.5 0.1 0.79 9.3 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 GAK67368.1 - 0.023 14.4 0.2 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain IIGP PF05049.13 GAK67368.1 - 0.032 13.3 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Acylphosphatase PF00708.18 GAK67368.1 - 0.045 14.1 0.1 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 Acylphosphatase AAA_16 PF13191.6 GAK67368.1 - 0.07 13.5 3.6 0.18 12.2 0.0 3.1 1 1 2 3 3 3 0 AAA ATPase domain ABM PF03992.16 GAK67369.1 - 1.8e-07 31.2 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PQ-loop PF04193.14 GAK67370.1 - 6.2e-18 64.3 11.5 1.8e-13 50.1 3.1 2.8 3 0 0 3 3 3 2 PQ loop repeat Comm PF15957.5 GAK67370.1 - 0.011 16.0 0.3 0.035 14.5 0.1 2.0 2 0 0 2 2 2 0 Commissureless GWT1 PF06423.12 GAK67370.1 - 0.096 12.8 0.2 2.1 8.5 0.2 2.7 1 1 1 2 2 2 0 GWT1 SARAF PF06682.12 GAK67371.1 - 4.5e-63 213.9 0.8 6.8e-63 213.3 0.8 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CPSase_L_D2 PF02786.17 GAK67372.1 - 6.8e-52 176.0 0.0 1.4e-51 175.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.22 GAK67372.1 - 9.9e-47 159.7 0.0 2.6e-46 158.3 0.0 1.7 1 1 0 1 1 1 1 Carboxyl transferase domain Biotin_carb_N PF00289.22 GAK67372.1 - 6.9e-34 116.7 0.2 9.9e-33 113.0 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAK67372.1 - 2.2e-21 76.0 0.0 5.6e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAK67372.1 - 3.8e-10 39.5 3.3 9e-10 38.2 3.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_ST PF14397.6 GAK67372.1 - 0.00014 21.2 0.1 0.00054 19.3 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 GAK67372.1 - 0.00047 19.9 7.5 0.022 14.6 1.4 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAK67372.1 - 0.0025 17.4 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAK67372.1 - 0.0098 16.0 0.0 0.052 13.6 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 GAK67372.1 - 0.068 13.9 2.3 0.32 11.7 0.7 2.8 2 1 1 3 3 3 0 HlyD family secretion protein HlyD_D23 PF16576.5 GAK67372.1 - 0.2 10.8 1.9 0.67 9.1 1.8 1.8 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion FHA PF00498.26 GAK67373.1 - 1e-07 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain HIT PF01230.23 GAK67374.1 - 6.2e-25 87.8 0.2 9.4e-25 87.2 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAK67374.1 - 2e-13 50.8 0.1 2.6e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAK67374.1 - 5.2e-05 23.1 0.0 8.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rotamase PF00639.21 GAK67375.1 - 3.7e-23 82.3 0.0 6.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAK67375.1 - 2e-20 73.5 0.0 3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAK67375.1 - 3.5e-06 27.9 0.0 5.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 GAK67375.1 - 4.5e-06 26.7 0.6 1.4e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 WW domain DUF4253 PF14062.6 GAK67375.1 - 0.037 14.2 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Ribosomal_L4 PF00573.22 GAK67376.1 - 0.023 14.4 0.2 0.044 13.5 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family YABBY PF04690.13 GAK67377.1 - 2.4e-09 38.0 0.1 2.5e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 GAK67377.1 - 1.6e-05 25.5 1.0 2e-05 25.1 1.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 GAK67377.1 - 0.00099 19.7 1.1 0.0017 18.9 0.8 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 GAK67377.1 - 0.0014 19.0 1.2 0.0014 19.0 1.2 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box Pkinase PF00069.25 GAK67378.1 - 4.2e-17 62.4 0.0 4.4e-13 49.2 0.0 5.2 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67378.1 - 1.3e-06 27.9 0.0 5.6e-05 22.5 0.0 2.7 3 1 0 3 3 3 1 Protein tyrosine kinase WD40 PF00400.32 GAK67379.1 - 0.004 18.0 2.7 0.55 11.2 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK67379.1 - 0.03 14.6 0.0 0.78 10.1 0.0 3.0 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAK67379.1 - 0.031 13.0 0.0 0.083 11.6 0.0 1.7 2 0 0 2 2 2 0 Nup133 N terminal like MMS1_N PF10433.9 GAK67379.1 - 0.076 11.6 0.0 6.4 5.3 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_L23eN PF03939.13 GAK67380.1 - 2.2e-21 75.8 11.1 6.2e-21 74.4 11.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GAK67380.1 - 4.6e-13 49.3 0.1 1.3e-12 47.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 RCDG1 PF15725.5 GAK67380.1 - 0.022 15.1 2.6 0.12 12.8 2.6 2.2 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein AA_permease PF00324.21 GAK67381.1 - 3.1e-128 428.4 43.9 3.8e-128 428.1 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK67381.1 - 5.1e-38 131.0 46.4 6.7e-38 130.6 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.20 GAK67384.1 - 8.1e-36 124.0 0.1 1.6e-35 123.0 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 GAK67384.1 - 8e-19 67.0 0.9 3.2e-09 36.2 0.1 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.7 GAK67384.1 - 3.5e-16 59.1 0.0 1e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.6 GAK67384.1 - 2.2e-13 49.8 1.6 3.7e-08 33.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 GAK67384.1 - 3.7e-10 39.3 0.0 3.7e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 GAK67384.1 - 6.4e-08 32.2 0.4 1.9e-07 30.7 0.4 1.9 1 0 0 1 1 1 1 WH2 motif SH3_10 PF17902.1 GAK67384.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.8 1 0 0 1 1 1 0 SH3 domain EF-hand_1 PF00036.32 GAK67384.1 - 0.017 14.7 0.9 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 GAK67384.1 - 0.024 15.1 0.0 0.086 13.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 GAK67384.1 - 0.15 12.1 0.0 37 4.6 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain PH_13 PF16652.5 GAK67384.1 - 0.66 9.8 5.7 0.96 9.2 0.1 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain NCE101 PF11654.8 GAK67385.1 - 9.2e-19 66.9 0.1 1.4e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Non-classical export protein 1 zf-RING_2 PF13639.6 GAK67386.1 - 6.5e-11 42.4 10.6 1e-10 41.8 10.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAK67386.1 - 1.2e-08 35.1 8.6 2.4e-08 34.1 8.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAK67386.1 - 1.9e-06 27.5 3.5 3.5e-06 26.6 3.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAK67386.1 - 6.4e-06 25.9 8.3 1e-05 25.3 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK67386.1 - 1.9e-05 24.5 7.3 3e-05 23.9 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAK67386.1 - 2e-05 24.6 4.1 4.4e-05 23.5 4.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAK67386.1 - 2e-05 24.3 9.4 3.4e-05 23.6 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAK67386.1 - 0.00053 19.8 7.4 0.00085 19.1 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAK67386.1 - 0.0028 17.5 6.0 0.0049 16.7 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-HC5HC2H PF13771.6 GAK67386.1 - 0.018 15.3 2.9 0.042 14.1 2.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAK67386.1 - 0.086 13.0 2.8 0.18 12.0 2.8 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 GAK67386.1 - 0.096 13.0 9.2 0.15 12.4 9.2 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 GAK67386.1 - 0.44 10.4 8.5 0.91 9.4 8.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 GAK67386.1 - 0.57 10.1 3.6 1.1 9.2 3.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK67386.1 - 0.59 10.2 6.4 1.2 9.2 6.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 GAK67386.1 - 0.81 9.8 2.0 1.5 8.9 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 GAK67386.1 - 1.8 8.2 7.6 3.5 7.3 7.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAK67386.1 - 2.5 8.3 11.3 4.5 7.5 11.3 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 GAK67386.1 - 9 6.5 5.5 30 4.9 5.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 GAK67386.1 - 9.1 6.3 9.4 15 5.5 9.4 1.4 1 0 0 1 1 1 0 PHD-finger PTPlike_phytase PF14566.6 GAK67388.1 - 1.1e-141 467.4 0.0 2.3e-49 167.5 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 GAK67388.1 - 2.5e-08 33.8 0.0 0.31 10.8 0.0 4.0 4 0 0 4 4 4 3 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GAK67388.1 - 1.2e-05 25.4 0.0 0.23 11.4 0.0 3.5 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAK67388.1 - 0.00014 21.6 0.2 0.72 9.4 0.0 3.3 3 0 0 3 3 3 2 Protein-tyrosine phosphatase HisG PF01634.18 GAK67389.1 - 4.3e-51 173.0 0.1 6.1e-51 172.5 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GAK67389.1 - 5.5e-26 90.5 0.1 1.2e-25 89.5 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 GAK67389.1 - 0.0055 16.7 0.1 0.081 12.9 0.1 2.3 1 1 0 1 1 1 1 NMT1/THI5 like Cation_efflux PF01545.21 GAK67390.1 - 3.8e-05 23.5 5.5 6.3e-05 22.8 5.5 1.4 1 0 0 1 1 1 1 Cation efflux family Pkinase PF00069.25 GAK67391.1 - 7.5e-69 232.0 0.0 9.6e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67391.1 - 1e-35 123.3 0.0 1.4e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short PF00106.25 GAK67391.1 - 9.5e-22 77.4 0.1 2.3e-21 76.1 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK67391.1 - 1.4e-15 57.5 0.4 3e-15 56.4 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Kinase-like PF14531.6 GAK67391.1 - 3.3e-09 36.5 0.0 5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAK67391.1 - 1.8e-06 27.0 0.1 3.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAK67391.1 - 3.1e-05 23.4 0.1 6.3e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAK67391.1 - 0.0025 17.4 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL KR PF08659.10 GAK67391.1 - 0.003 17.5 0.2 0.0087 16.0 0.2 1.9 1 1 0 1 1 1 1 KR domain APH PF01636.23 GAK67391.1 - 0.0063 16.5 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1776 PF08643.10 GAK67391.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TetR_C_27 PF17935.1 GAK67391.1 - 0.05 13.7 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NmrA PF05368.13 GAK67391.1 - 0.13 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family DAGK_cat PF00781.24 GAK67392.1 - 9.6e-24 83.4 0.0 1.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RibD_C PF01872.17 GAK67393.1 - 9.6e-33 113.7 0.1 1.2e-32 113.4 0.1 1.1 1 0 0 1 1 1 1 RibD C-terminal domain HMG_box PF00505.19 GAK67394.1 - 1.2e-10 41.7 4.3 1.3e-09 38.3 4.3 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAK67394.1 - 0.0023 18.5 1.6 0.0051 17.4 1.6 1.6 1 0 0 1 1 1 1 HMG-box domain IL28A PF15177.6 GAK67394.1 - 0.15 11.9 0.5 0.27 11.1 0.5 1.3 1 0 0 1 1 1 0 Interleukin-28A ubiquitin PF00240.23 GAK67395.1 - 7.3e-26 89.7 0.4 8.1e-26 89.6 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAK67395.1 - 1.9e-15 56.4 0.4 2.1e-15 56.3 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAK67395.1 - 0.00016 22.0 0.1 0.00047 20.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAK67395.1 - 0.00055 19.8 0.0 0.00065 19.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAK67395.1 - 0.03 14.7 0.2 0.032 14.6 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 GAK67395.1 - 0.11 12.6 0.6 3.5 7.8 0.6 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain tRNA-synt_His PF13393.6 GAK67396.1 - 3.3e-41 141.6 0.2 1.3e-34 119.9 0.0 3.1 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GAK67396.1 - 1.1e-08 35.1 0.2 3.5e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 GAK67396.1 - 1.1e-07 31.7 0.5 2.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs APG6_N PF17675.1 GAK67396.1 - 0.0093 16.5 2.9 0.022 15.3 2.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region tRNA-synt_2 PF00152.20 GAK67396.1 - 0.1 11.7 0.3 1.7 7.7 0.1 2.6 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) PORR PF11955.8 GAK67396.1 - 0.14 11.1 0.0 0.34 9.8 0.0 1.5 2 0 0 2 2 2 0 Plant organelle RNA recognition domain WHEP-TRS PF00458.20 GAK67396.1 - 0.22 11.7 4.9 1.1 9.5 4.9 2.3 1 0 0 1 1 1 0 WHEP-TRS domain Ribosomal_60s PF00428.19 GAK67396.1 - 4.1 8.1 9.4 0.13 12.8 2.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Use1 PF09753.9 GAK67397.1 - 3.3e-13 50.0 0.1 8e-13 48.7 0.0 1.8 1 1 1 2 2 2 1 Membrane fusion protein Use1 SNARE PF05739.19 GAK67397.1 - 0.26 11.3 1.9 0.31 11.1 0.1 2.1 2 1 0 2 2 2 0 SNARE domain zf-HC5HC2H_2 PF13832.6 GAK67398.1 - 6.3e-33 113.2 6.3 6.3e-33 113.2 6.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 GAK67398.1 - 2.1e-24 86.7 0.1 2.1e-24 86.7 0.1 3.0 4 0 0 4 4 4 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 GAK67398.1 - 3.7e-24 84.8 4.0 3.7e-24 84.8 4.0 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 GAK67398.1 - 2.1e-17 63.0 0.1 3.8e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 GAK67398.1 - 1.1e-14 53.7 2.6 1.1e-14 53.7 2.6 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 GAK67398.1 - 5.3e-12 46.0 1.4 8.2e-12 45.4 0.3 2.0 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 GAK67398.1 - 5.4e-11 42.2 5.7 5.4e-11 42.2 5.7 2.7 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 GAK67398.1 - 0.0032 17.1 0.7 0.0032 17.1 0.7 2.6 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 GAK67398.1 - 0.013 15.3 0.4 0.013 15.3 0.4 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 GAK67398.1 - 0.049 13.9 14.5 0.1 13.0 5.7 2.5 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.6 GAK67398.1 - 0.84 9.6 17.5 0.043 13.7 3.0 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Coiled-coil_56 PF09813.9 GAK67399.1 - 2.3e-05 24.3 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Scramblase PF03803.15 GAK67400.1 - 8.2e-62 208.4 0.0 1.1e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Scramblase Romo1 PF10247.9 GAK67401.1 - 2.1e-24 85.7 11.7 2.8e-24 85.3 11.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Macro PF01661.21 GAK67402.1 - 3.9e-42 143.0 0.1 6.3e-42 142.4 0.1 1.3 1 0 0 1 1 1 1 Macro domain AP_endonuc_2 PF01261.24 GAK67402.1 - 0.065 12.7 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF1955 PF09205.10 GAK67402.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Peptidase_M24 PF00557.24 GAK67403.1 - 3.3e-39 134.7 0.4 4.5e-39 134.3 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 GAK67403.1 - 0.0027 17.9 9.1 0.0041 17.3 9.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein TFIIF_alpha PF05793.12 GAK67403.1 - 0.0045 15.7 10.6 0.0062 15.2 10.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF3_subunit PF08597.10 GAK67403.1 - 0.005 16.8 7.6 0.0082 16.1 7.6 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Drc1-Sld2 PF11719.8 GAK67403.1 - 0.069 12.7 8.3 0.09 12.3 8.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 GAK67403.1 - 0.24 9.6 7.7 0.34 9.1 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAK67403.1 - 0.3 9.3 7.7 0.39 8.9 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 GAK67403.1 - 0.43 10.3 4.4 0.85 9.3 4.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNA_pol_Rpc4 PF05132.14 GAK67403.1 - 0.72 10.3 4.7 1.2 9.5 4.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4604 PF15377.6 GAK67403.1 - 1.1 9.7 16.0 2 8.8 16.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DNA_pol_phi PF04931.13 GAK67403.1 - 1.5 6.9 7.8 2.2 6.3 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GAK67403.1 - 3.4 8.1 13.1 7.4 7.0 13.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PGA2 PF07543.12 GAK67403.1 - 3.4 7.7 12.7 0.14 12.1 5.6 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 PBP1_TM PF14812.6 GAK67403.1 - 6.4 7.2 18.1 0.14 12.5 10.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GATase_6 PF13522.6 GAK67404.1 - 3.2e-14 53.3 0.0 8.5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAK67404.1 - 2.1e-10 40.6 0.0 4.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GAK67404.1 - 6e-10 38.9 0.1 1.4e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 GAK67404.1 - 5.3e-06 25.5 0.0 9.9e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Ribosomal_60s PF00428.19 GAK67404.1 - 4.3 8.0 10.2 10 6.8 9.4 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein cwf18 PF08315.12 GAK67405.1 - 3.4e-28 99.0 9.0 5.8e-28 98.2 9.0 1.4 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor YL1 PF05764.13 GAK67406.1 - 1.5e-50 172.6 21.6 1.5e-50 172.6 21.6 2.9 3 0 0 3 3 3 2 YL1 nuclear protein YL1_C PF08265.11 GAK67406.1 - 1.3e-13 50.4 0.8 2.2e-13 49.7 0.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_25 PF13649.6 GAK67407.1 - 0.031 15.0 0.1 4.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain KAR9 PF08580.10 GAK67407.1 - 1.1 7.7 3.2 1.5 7.2 3.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF1970 PF09301.10 GAK67408.1 - 0.49 10.7 5.4 0.084 13.1 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1970) zf-C2H2 PF00096.26 GAK67408.1 - 1.2 9.7 4.0 2.8 8.6 4.0 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3808 PF10300.9 GAK67409.1 - 1.4e-73 248.3 0.5 2.3e-73 247.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.20 GAK67409.1 - 1.2e-33 116.1 0.1 2.1e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAK67409.1 - 4.4e-12 46.3 0.0 1e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAK67409.1 - 3.8e-10 39.8 0.5 1.2e-09 38.2 0.5 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ribosomal_60s PF00428.19 GAK67409.1 - 0.001 19.6 11.6 0.001 19.6 11.6 5.5 4 1 1 5 5 3 1 60s Acidic ribosomal protein TPR_12 PF13424.6 GAK67409.1 - 0.0012 19.1 0.7 12 6.3 0.9 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAK67409.1 - 0.0052 16.8 10.4 1.2 9.5 1.0 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAK67409.1 - 0.05 14.2 3.9 0.79 10.5 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAK67409.1 - 0.13 12.5 6.9 0.68 10.3 0.4 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAK67409.1 - 1.1 9.4 4.6 3.5 7.9 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAK67409.1 - 3.6 7.6 8.3 0.7 9.8 0.2 4.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DIOX_N PF14226.6 GAK67410.1 - 1.8e-12 48.1 0.0 4.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAK67410.1 - 3e-12 46.9 0.0 1.2e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.21 GAK67411.1 - 3.7e-43 148.1 0.6 2.4e-41 142.1 0.3 2.2 2 0 0 2 2 2 2 Amidase Amidohydro_1 PF01979.20 GAK67413.1 - 2.9e-63 214.3 0.2 5.4e-63 213.4 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 GAK67413.1 - 1.2e-56 190.3 0.4 2.2e-56 189.4 0.4 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 GAK67413.1 - 8.1e-41 138.3 1.1 1.2e-40 137.8 0.3 1.8 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 GAK67413.1 - 2.3e-33 114.1 0.0 5.3e-33 113.0 0.0 1.6 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 GAK67413.1 - 4.9e-07 29.6 0.3 1.7e-05 24.5 0.0 3.1 3 1 0 3 3 3 1 Amidohydrolase family Flavin_Reduct PF01613.18 GAK67414.1 - 8e-34 116.9 0.3 1e-33 116.6 0.3 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.20 GAK67415.1 - 4.8e-37 128.0 0.0 2.8e-36 125.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 GAK67415.1 - 0.0018 18.0 0.1 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 GAK67415.1 - 0.034 13.4 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Seipin PF06775.14 GAK67417.1 - 2.4e-51 174.7 0.0 4e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF2722 PF10846.8 GAK67417.1 - 1.7e-05 24.0 0.7 1.7e-05 24.0 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 GAK67417.1 - 0.017 15.7 8.8 0.017 15.7 8.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 GAK67417.1 - 0.28 11.1 6.3 0.57 10.1 6.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 GAK67417.1 - 6 6.4 23.9 11 5.6 23.9 1.3 1 0 0 1 1 1 0 Spt20 family Glyco_hydro_92 PF07971.12 GAK67418.1 - 7.7e-115 384.4 0.0 9.3e-115 384.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAK67418.1 - 6.8e-28 98.2 0.0 1.1e-27 97.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Aldo_ket_red PF00248.21 GAK67419.1 - 3.7e-34 118.3 0.1 7.1e-34 117.3 0.1 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family YflT PF11181.8 GAK67419.1 - 0.019 15.5 0.2 0.15 12.6 0.0 2.5 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF3128 PF11326.8 GAK67419.1 - 0.023 15.0 0.9 0.066 13.6 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Ndufs5 PF10200.9 GAK67419.1 - 0.08 13.2 0.5 0.19 12.0 0.5 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TAP42 PF04177.12 GAK67420.1 - 2e-77 260.5 0.0 2.4e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family RRXRR PF14239.6 GAK67420.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 RRXRR protein DEC-1_N PF04625.13 GAK67420.1 - 2.3 7.1 10.2 0.19 10.7 3.9 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Ribosomal_L10 PF00466.20 GAK67422.1 - 3.4e-25 88.1 0.0 8e-25 86.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 GAK67422.1 - 3.1e-21 75.8 9.4 1.1e-20 74.0 8.6 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 GAK67422.1 - 3.5e-21 75.0 0.0 5.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P LIM PF00412.22 GAK67423.1 - 7e-13 48.6 31.4 9.1e-06 25.8 1.6 6.4 6 0 0 6 6 6 4 LIM domain Ribosomal_L32p PF01783.23 GAK67423.1 - 0.078 13.2 2.1 6.5 7.1 0.2 3.2 2 0 0 2 2 2 0 Ribosomal L32p protein family Mut7-C PF01927.16 GAK67423.1 - 1.9 8.6 12.0 2.4 8.3 0.5 3.5 3 0 0 3 3 3 0 Mut7-C RNAse domain CxC3 PF18804.1 GAK67423.1 - 2.2 8.1 4.8 0.54 10.1 0.1 2.4 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases GDP_Man_Dehyd PF16363.5 GAK67424.1 - 6.8e-43 147.3 0.0 8.5e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAK67424.1 - 7.7e-42 143.4 0.0 1e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK67424.1 - 9.8e-11 41.2 0.0 4.5e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAK67424.1 - 9.4e-10 38.0 0.0 1.7e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAK67424.1 - 1.7e-06 27.4 0.0 7.3e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAK67424.1 - 8.8e-05 21.8 0.0 0.00021 20.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAK67424.1 - 0.00029 20.8 0.0 0.0011 18.9 0.0 1.8 1 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 GAK67424.1 - 0.00043 20.3 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAK67424.1 - 0.055 13.3 0.1 0.24 11.3 0.0 2.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrpF PF04303.13 GAK67425.1 - 9.8e-53 179.4 0.5 4.9e-38 131.1 0.1 2.4 2 1 0 2 2 2 2 PrpF protein DUF5642 PF18702.1 GAK67425.1 - 0.03 14.1 0.1 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5642) Acyltransferase PF01553.21 GAK67426.1 - 1.7e-22 79.5 0.0 2.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 GAK67426.1 - 6.2e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus AIM5 PF17050.5 GAK67427.1 - 6.2e-08 33.3 0.4 1e-07 32.6 0.4 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 NatB_MDM20 PF09797.9 GAK67428.1 - 1.5e-97 327.0 0.7 2.6e-97 326.2 0.1 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit BTAD PF03704.17 GAK67428.1 - 0.0018 18.8 0.8 0.0018 18.8 0.8 4.1 4 0 0 4 4 4 1 Bacterial transcriptional activator domain DUF5578 PF17741.1 GAK67428.1 - 0.032 13.7 1.2 0.056 12.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5578) RPOL_N PF14700.6 GAK67428.1 - 0.095 12.1 0.1 0.22 10.9 0.1 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal TPR_5 PF12688.7 GAK67428.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.8 4 1 1 5 5 5 0 Tetratrico peptide repeat DUF1708 PF08101.11 GAK67429.1 - 9.6e-17 61.2 0.0 4.7e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 GAK67429.1 - 5.3e-07 29.6 0.0 0.00032 20.5 0.0 2.5 2 0 0 2 2 2 2 RhoGAP domain Pyridoxal_deC PF00282.19 GAK67430.1 - 6.3e-66 222.6 0.0 9.2e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAK67430.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF4576 PF15144.6 GAK67432.1 - 0.1 12.5 0.3 0.1 12.5 0.3 5.5 2 2 3 5 5 5 0 Domain of unknown function (DUF4576) CDC45 PF02724.14 GAK67432.1 - 2.2 6.4 40.4 0.02 13.2 19.9 2.1 2 0 0 2 2 2 0 CDC45-like protein MTHFR PF02219.17 GAK67433.1 - 2.4e-102 342.1 0.0 6.4e-84 281.7 0.0 2.1 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase pPIWI_RE_REase PF18154.1 GAK67433.1 - 0.015 15.2 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 REase associating with pPIWI_RE PLDc_2 PF13091.6 GAK67434.1 - 3.7e-18 65.7 0.0 1.7e-12 47.3 0.0 2.8 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 GAK67434.1 - 0.011 15.9 0.1 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif Colicin-DNase PF12639.7 GAK67434.1 - 0.28 12.0 1.9 0.67 10.8 0.0 2.6 4 0 0 4 4 4 0 DNase/tRNase domain of colicin-like bacteriocin Cpn60_TCP1 PF00118.24 GAK67435.1 - 3.9e-165 550.2 3.8 4.4e-165 550.0 3.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltr_RsmB-F PF01189.17 GAK67437.1 - 3.9e-15 56.0 0.3 5.6e-14 52.3 0.1 2.5 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Pyrophosphatase PF00719.19 GAK67438.1 - 6.4e-59 198.3 0.3 8.5e-59 197.9 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Phage_TTP_12 PF16461.5 GAK67438.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP COesterase PF00135.28 GAK67439.1 - 9.8e-87 291.9 0.0 1.2e-86 291.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK67439.1 - 9.1e-11 42.0 2.5 0.00013 21.9 0.4 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 GAK67439.1 - 0.11 11.4 0.6 0.78 8.6 0.6 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF5465 PF17553.2 GAK67439.1 - 2.4 8.9 4.7 15 6.5 4.7 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5465) OTU PF02338.19 GAK67440.1 - 0.0002 21.8 0.0 0.00032 21.2 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 GAK67440.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Glyco_hydro_3_C PF01915.22 GAK67441.1 - 6.1e-43 147.2 0.0 1.2e-42 146.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAK67441.1 - 2.4e-35 122.4 0.0 3.1e-34 118.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAK67441.1 - 4.7e-25 87.5 0.6 9.1e-25 86.6 0.6 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 GAK67443.1 - 3.2e-108 362.5 23.9 4.8e-108 361.9 23.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK67443.1 - 2e-26 92.8 70.6 4.5e-24 85.0 41.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Orai-1 PF07856.12 GAK67443.1 - 0.12 12.1 2.2 1.8 8.2 0.4 2.4 2 0 0 2 2 2 0 Mediator of CRAC channel activity Glyco_hydro_76 PF03663.14 GAK67444.1 - 6e-45 154.3 6.9 7.1e-45 154.1 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAK67444.1 - 0.0039 16.3 2.1 0.27 10.2 0.0 2.7 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Sda PF08970.10 GAK67444.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Sporulation inhibitor A Glyco_hydro_17 PF00332.18 GAK67445.1 - 2.1e-06 27.6 0.6 4.6e-06 26.4 0.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF1043 PF06295.12 GAK67445.1 - 0.024 14.6 2.9 1 9.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Insulin_TMD PF17870.1 GAK67445.1 - 0.047 13.8 0.5 0.094 12.8 0.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Zip PF02535.22 GAK67445.1 - 0.082 12.1 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Gypsy PF07253.11 GAK67445.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein DUF3172 PF11371.8 GAK67445.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Flp1_like PF16982.5 GAK67445.1 - 0.3 10.5 5.1 0.53 9.7 5.1 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain EphA2_TM PF14575.6 GAK67445.1 - 0.54 11.2 0.0 0.54 11.2 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAD_binding_7 PF03441.14 GAK67446.1 - 1.3e-73 246.8 0.4 2.1e-73 246.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAK67446.1 - 3.4e-44 150.7 0.1 6.6e-44 149.8 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Pribosyltran_N PF13793.6 GAK67447.1 - 9.4e-45 151.3 0.2 2.6e-44 149.9 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAK67447.1 - 9e-40 136.7 2.4 1e-32 113.7 0.2 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAK67447.1 - 1.3e-14 54.1 0.9 6.5e-14 51.8 0.4 2.4 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAK67447.1 - 0.061 12.8 0.1 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase DUF2007 PF09413.10 GAK67447.1 - 0.069 13.3 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Pil1 PF13805.6 GAK67448.1 - 1.1e-24 87.4 2.5 2e-24 86.5 2.5 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 FmiP_Thoc5 PF09766.9 GAK67448.1 - 0.00072 18.9 1.6 0.0012 18.2 1.6 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Vps51 PF08700.11 GAK67448.1 - 0.048 13.7 0.5 0.1 12.7 0.5 1.6 1 0 0 1 1 1 0 Vps51/Vps67 AAA_13 PF13166.6 GAK67448.1 - 0.1 11.2 2.9 0.15 10.7 2.9 1.1 1 0 0 1 1 1 0 AAA domain Gp-FAR-1 PF05823.12 GAK67448.1 - 0.23 11.8 2.3 0.31 11.4 0.4 2.1 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4515 PF14988.6 GAK67448.1 - 0.35 10.7 3.0 0.3 10.9 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) Spc7 PF08317.11 GAK67448.1 - 0.53 9.1 4.0 0.38 9.6 2.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 GAK67448.1 - 2.8 8.5 5.7 0.32 11.5 0.9 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region NIPSNAP PF07978.13 GAK67449.1 - 1.1e-40 137.9 2.2 4.3e-29 100.8 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Pyridoxal_deC PF00282.19 GAK67450.1 - 6.6e-84 281.8 0.0 2.3e-60 204.3 0.0 2.5 1 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Gpr1_Fun34_YaaH PF01184.19 GAK67450.1 - 3.4e-36 124.8 18.4 6.7e-36 123.8 18.4 1.4 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aminotran_1_2 PF00155.21 GAK67450.1 - 0.042 13.0 0.0 1.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Aminotransferase class I and II Gpr1_Fun34_YaaH PF01184.19 GAK67451.1 - 1.4e-70 237.1 20.9 1.8e-70 236.8 20.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BCDHK_Adom3 PF10436.9 GAK67452.1 - 4.3e-44 150.2 0.0 5.9e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAK67452.1 - 9.7e-09 35.7 0.0 6.3e-08 33.1 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAK67452.1 - 8.1e-06 25.7 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.29 GAK67453.1 - 1.3e-14 54.7 0.0 3.2e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAK67453.1 - 3.7e-11 43.7 0.0 9.9e-10 39.1 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAK67453.1 - 2e-07 31.4 0.0 4.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 GAK67453.1 - 5e-06 26.6 0.2 1.2e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 GAK67453.1 - 0.00047 20.5 0.3 0.0045 17.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain Cdc6_C PF09079.11 GAK67453.1 - 0.0023 17.9 0.1 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain PIF1 PF05970.14 GAK67453.1 - 0.013 14.7 0.0 0.09 11.9 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase AAA_11 PF13086.6 GAK67453.1 - 0.02 14.7 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAK67453.1 - 0.024 14.4 0.2 0.057 13.1 0.2 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAK67453.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 GAK67453.1 - 0.091 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 GAK67453.1 - 0.11 12.7 0.0 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glyco_transf_22 PF03901.17 GAK67454.1 - 1.3e-65 222.3 17.5 6.1e-64 216.8 16.6 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family SPC25 PF06703.11 GAK67455.1 - 7.5e-45 152.6 0.0 8.7e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RRM_1 PF00076.22 GAK67456.1 - 7.7e-11 41.7 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 GAK67456.1 - 1.1 8.8 17.9 2 8.0 17.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 GAK67456.1 - 9.8 3.1 5.9 12 2.8 5.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2417 PF10329.9 GAK67457.1 - 1.7e-16 60.4 0.1 2.8e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Cytochrom_B561 PF03188.16 GAK67457.1 - 0.045 13.9 1.5 0.15 12.2 1.5 1.8 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF1270 PF06900.11 GAK67457.1 - 1.3 9.4 3.8 3.4 8.1 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Nuc_sug_transp PF04142.15 GAK67458.1 - 3e-80 269.7 12.3 1.8e-69 234.3 9.9 2.9 2 1 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 GAK67458.1 - 5.6e-06 25.8 12.4 0.00042 19.6 0.5 2.5 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.20 GAK67458.1 - 0.0011 19.1 2.0 0.0011 19.1 2.0 3.0 3 0 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 GAK67458.1 - 0.12 11.7 9.4 0.32 10.3 0.3 2.5 2 0 0 2 2 2 0 Triose-phosphate Transporter family CRT-like PF08627.10 GAK67458.1 - 1.2 8.0 8.8 0.45 9.4 1.1 2.5 3 0 0 3 3 3 0 CRT-like, chloroquine-resistance transporter-like p47_phox_C PF08944.11 GAK67461.1 - 5.8 6.4 13.4 2.5 7.6 0.7 2.5 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Peptidase_M36 PF02128.15 GAK67462.1 - 2e-147 491.2 0.3 3.3e-147 490.5 0.3 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 GAK67462.1 - 2.3e-13 49.7 0.0 4.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Nup188 PF10487.9 GAK67463.1 - 1.1e-34 119.6 0.0 2e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 GAK67463.1 - 0.0047 15.8 0.2 0.0091 14.9 0.2 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain ThiF PF00899.21 GAK67464.1 - 6e-66 222.3 0.0 8.1e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 GAK67464.1 - 8.4e-24 83.5 0.0 1.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 GAK67464.1 - 0.016 15.3 0.3 0.03 14.4 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAK67464.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Prim_Zn_Ribbon PF08273.12 GAK67464.1 - 0.11 12.7 0.2 0.29 11.4 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase ApbA PF02558.16 GAK67464.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 GAK67464.1 - 0.13 12.9 0.2 0.38 11.4 0.2 1.8 1 0 0 1 1 1 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 GAK67464.1 - 0.19 11.6 0.1 13 5.6 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Cellulase PF00150.18 GAK67465.1 - 1.7e-16 60.5 4.9 2.5e-16 59.9 4.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF515 PF04415.12 GAK67465.1 - 4.4 5.6 4.5 6.8 5.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PI3_PI4_kinase PF00454.27 GAK67466.1 - 2.5e-32 112.7 0.0 5.2e-21 75.6 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAK67466.1 - 1e-24 87.0 0.1 1.9e-24 86.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ras PF00071.22 GAK67467.1 - 9e-60 200.9 1.1 1.2e-59 200.5 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK67467.1 - 3.5e-37 127.3 0.1 6.2e-37 126.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK67467.1 - 1.2e-15 57.4 0.2 1.5e-15 57.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAK67467.1 - 1.5e-06 27.9 0.4 6.6e-06 25.8 0.4 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAK67467.1 - 9.7e-06 25.6 0.1 0.022 14.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAK67467.1 - 1.2e-05 24.9 0.1 1.7e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAK67467.1 - 5.8e-05 23.2 0.1 0.00012 22.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAK67467.1 - 6.6e-05 22.4 0.4 8.9e-05 21.9 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FlgH PF02107.16 GAK67467.1 - 0.019 14.6 1.0 0.029 14.0 1.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein FeoB_N PF02421.18 GAK67467.1 - 0.049 13.2 0.0 2.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 GAK67467.1 - 0.08 13.2 0.1 4.5 7.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2514 PF10721.9 GAK67467.1 - 0.1 12.6 2.1 0.16 12.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TniB PF05621.11 GAK67467.1 - 0.11 11.9 0.1 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TetR_C_16 PF17920.1 GAK67467.1 - 0.15 12.3 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Transket_pyr PF02779.24 GAK67469.1 - 2.8e-46 157.4 0.0 4.7e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAK67469.1 - 1.1e-36 125.4 0.4 2.8e-36 124.1 0.4 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ser_hydrolase PF06821.13 GAK67469.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase CK_II_beta PF01214.18 GAK67470.1 - 5.2e-81 270.8 0.0 7.1e-81 270.4 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PNP_UDP_1 PF01048.20 GAK67471.1 - 5.7e-39 133.8 1.4 8.3e-39 133.2 1.4 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily G-gamma PF00631.22 GAK67472.1 - 1.4e-19 69.8 0.2 4.1e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 GGL domain F-box-like PF12937.7 GAK67472.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.1 3 0 0 3 3 3 0 F-box-like Iso_dh PF00180.20 GAK67473.1 - 4.3e-73 246.5 0.0 5.2e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3435 PF11917.8 GAK67474.1 - 4.5e-20 72.0 0.0 6.9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Chitin_synth_2 PF03142.15 GAK67475.1 - 3.8e-17 62.1 0.2 4.1e-15 55.4 0.2 2.4 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAK67475.1 - 0.00021 21.2 4.0 0.00048 20.1 4.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK67475.1 - 0.068 13.1 1.8 1.4 8.8 0.1 2.6 2 1 0 2 2 2 0 Glycosyltransferase like family 2 UDPG_MGDP_dh PF00984.19 GAK67476.1 - 9.9e-21 73.8 0.1 5.7e-20 71.3 0.0 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 GAK67476.1 - 3e-16 59.5 0.1 1.5e-14 54.0 0.0 2.7 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 GAK67476.1 - 3.1e-05 24.6 0.1 0.00046 20.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain UDPG_MGDP_dh_C PF03720.15 GAK67476.1 - 7.6e-05 23.1 0.1 0.00038 20.8 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Epimerase PF01370.21 GAK67476.1 - 0.00078 19.0 0.0 0.12 11.9 0.0 3.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 GAK67476.1 - 0.0011 19.1 0.0 0.0031 17.7 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 GAK67476.1 - 0.0012 19.0 0.0 0.0043 17.3 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_11 PF08241.12 GAK67476.1 - 0.0014 19.3 0.8 0.048 14.3 0.1 3.1 3 0 0 3 3 3 1 Methyltransferase domain GFO_IDH_MocA PF01408.22 GAK67476.1 - 0.026 15.3 0.1 0.17 12.7 0.0 2.4 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_M56 PF05569.11 GAK67477.1 - 0.23 10.6 2.3 5.6 6.1 1.9 2.2 2 0 0 2 2 2 0 BlaR1 peptidase M56 Consortin_C PF15281.6 GAK67477.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 Consortin C-terminus Cutinase PF01083.22 GAK67478.1 - 5.9e-28 98.0 2.2 1.3e-27 96.9 2.2 1.6 1 1 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAK67478.1 - 0.034 13.7 0.1 0.06 12.9 0.1 1.4 1 1 0 1 1 1 0 PE-PPE domain DUF697 PF05128.12 GAK67479.1 - 1 9.0 7.9 0.069 12.9 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF697) YchF-GTPase_C PF06071.13 GAK67480.1 - 2.2e-33 114.3 1.0 1.1e-32 112.1 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAK67480.1 - 7.6e-17 61.4 0.0 3.2e-16 59.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAK67480.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 GAK67480.1 - 0.19 12.3 1.0 22 5.6 0.9 2.3 2 0 0 2 2 2 0 AAA domain DNA_pol_A_exo1 PF01612.20 GAK67481.1 - 2.4e-39 134.9 1.7 9e-39 133.0 0.2 2.1 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 GAK67481.1 - 1.7e-25 89.5 0.3 6.2e-25 87.7 0.3 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 GAK67481.1 - 1.4e-11 44.2 0.2 3.1e-11 43.1 0.2 1.7 1 0 0 1 1 1 1 HRDC domain RNase_HII PF01351.18 GAK67482.1 - 4.8e-45 153.8 0.0 1.3e-40 139.3 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII DUF3449 PF11931.8 GAK67483.1 - 3.2e-66 222.7 0.0 6.9e-66 221.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 GAK67483.1 - 5e-23 81.4 0.2 1.4e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 GAK67483.1 - 1.7e-07 31.0 0.0 3.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 GAK67483.1 - 0.0004 20.6 5.4 0.014 15.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAK67483.1 - 0.0014 19.0 1.2 0.012 16.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAK67483.1 - 0.0033 17.7 0.1 4.3 7.7 0.2 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) DEAD PF00270.29 GAK67484.1 - 1.1e-43 149.0 0.1 1.9e-43 148.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK67484.1 - 1.2e-32 112.6 0.2 5.1e-32 110.5 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK67484.1 - 0.0006 19.9 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAK67484.1 - 0.023 13.5 0.0 0.64 8.7 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 GAK67484.1 - 0.035 14.5 0.6 0.1 12.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAK67484.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Npun_R1517 PF18068.1 GAK67487.1 - 0.018 15.4 0.3 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 Npun R1517 Glyco_hydro_115 PF15979.5 GAK67488.1 - 3.2e-127 424.7 0.1 4.4e-127 424.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 GAK67488.1 - 2e-31 109.1 0.0 4.1e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain DUF4091 PF13320.6 GAK67489.1 - 0.038 14.1 1.6 0.12 12.5 1.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) SOG2 PF10428.9 GAK67489.1 - 0.6 9.3 27.3 0.92 8.6 27.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 GAK67489.1 - 0.83 8.4 12.2 1.1 8.0 12.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAN_3 PF08277.12 GAK67489.1 - 3.1 7.7 5.6 0.61 9.9 1.1 2.2 2 0 0 2 2 2 0 PAN-like domain ORC6 PF05460.13 GAK67489.1 - 4.3 6.5 14.6 7.4 5.7 14.6 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SPX PF03105.19 GAK67489.1 - 6.2 6.6 15.2 10 5.9 15.2 1.2 1 0 0 1 1 1 0 SPX domain Pro-kuma_activ PF09286.11 GAK67490.1 - 4.4e-34 117.8 0.0 8.4e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAK67490.1 - 0.00049 19.5 0.9 0.00078 18.8 0.9 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_17 PF00332.18 GAK67491.1 - 2.1e-10 40.7 0.9 5.3e-08 32.8 0.1 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 Wzz PF02706.15 GAK67491.1 - 0.016 15.5 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Chain length determinant protein Ribosomal_S11 PF00411.19 GAK67492.1 - 6.4e-12 45.9 0.0 1.6e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S11 Raftlin PF15250.6 GAK67492.1 - 0.27 9.9 1.5 0.36 9.5 1.5 1.1 1 0 0 1 1 1 0 Raftlin SPX PF03105.19 GAK67492.1 - 0.6 10.0 9.2 0.7 9.7 9.2 1.1 1 0 0 1 1 1 0 SPX domain COG6 PF06419.11 GAK67493.1 - 8.1e-155 516.5 0.0 1e-154 516.2 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Tektin PF03148.14 GAK67493.1 - 0.049 12.4 0.1 0.11 11.2 0.1 1.5 1 0 0 1 1 1 0 Tektin family Fes1 PF08609.10 GAK67493.1 - 0.16 12.9 1.9 1.1 10.2 0.0 3.2 3 1 1 4 4 4 0 Nucleotide exchange factor Fes1 DUF92 PF01940.16 GAK67494.1 - 8.5e-72 241.4 11.9 1e-71 241.1 11.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 PTR2 PF00854.21 GAK67495.1 - 8.7e-74 248.7 9.7 1.3e-73 248.1 9.7 1.2 1 0 0 1 1 1 1 POT family FG-GAP PF01839.23 GAK67495.1 - 0.74 10.0 3.4 2.4 8.4 3.4 1.9 1 1 0 1 1 1 0 FG-GAP repeat Cation_efflux PF01545.21 GAK67496.1 - 1.6e-46 158.6 12.7 1.6e-46 158.6 12.7 2.7 3 1 0 3 3 3 1 Cation efflux family Zip PF02535.22 GAK67496.1 - 0.5 9.5 28.8 0.27 10.4 12.3 3.8 4 0 0 4 4 4 0 ZIP Zinc transporter EF-hand_1 PF00036.32 GAK67497.1 - 7e-21 72.2 0.0 2.1e-05 23.7 0.0 4.6 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAK67497.1 - 5.5e-19 66.4 0.1 5.8e-06 25.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 GAK67497.1 - 1.4e-16 60.7 0.1 2.5e-07 31.0 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAK67497.1 - 4.1e-16 57.7 0.0 0.00036 19.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAK67497.1 - 6.4e-14 51.5 0.2 6.6e-07 29.1 0.0 3.8 3 2 0 3 3 3 2 EF-hand domain pair Mucin-like PF16058.5 GAK67497.1 - 6.8e-06 26.1 19.5 6.8e-06 26.1 19.5 2.0 1 1 0 1 1 1 1 Mucin-like Extensin_2 PF04554.13 GAK67497.1 - 0.31 11.2 32.2 0.089 12.9 20.7 3.0 1 1 2 3 3 3 0 Extensin-like region PEHE PF15275.6 GAK67498.1 - 0.00015 22.4 7.7 0.00015 22.4 7.7 5.0 6 2 0 6 6 6 1 PEHE domain SAS4 PF15460.6 GAK67498.1 - 0.0033 17.5 1.4 0.0033 17.5 1.4 2.1 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 Mad3_BUB1_I PF08311.12 GAK67499.1 - 2.3e-41 140.6 0.2 4e-41 139.9 0.2 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 GAK67499.1 - 6.3e-08 32.3 0.0 2.4e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 GAK67499.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Exo_endo_phos PF03372.23 GAK67500.1 - 3.1e-12 46.5 0.0 4.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TAF4 PF05236.14 GAK67500.1 - 2.6 7.7 6.1 3.8 7.2 6.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Glyco_hydro_43 PF04616.14 GAK67502.1 - 2.7e-62 210.7 1.6 4e-62 210.1 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAK67502.1 - 1.1e-14 54.6 0.1 2e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PolyA_pol PF01743.20 GAK67503.1 - 0.09 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Poly A polymerase head domain DHDPS PF00701.22 GAK67504.1 - 5.1e-38 130.4 0.0 6e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 GAK67505.1 - 2e-29 102.6 22.2 3e-29 102.0 22.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 GAK67505.1 - 8.3 4.6 13.5 0.023 13.0 2.6 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Fungal_trans PF04082.18 GAK67506.1 - 1.3e-19 70.3 0.0 2.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK67506.1 - 1.3e-06 28.5 12.2 2.9e-06 27.3 12.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAK67507.1 - 3e-22 79.1 0.5 1.5e-19 70.2 1.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Peptidase_M20 PF01546.28 GAK67507.1 - 9.7e-22 77.7 0.1 1.8e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 adh_short_C2 PF13561.6 GAK67507.1 - 8.2e-15 55.0 0.3 1e-13 51.4 0.6 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase M20_dimer PF07687.14 GAK67507.1 - 4.4e-14 52.3 0.0 1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain KR PF08659.10 GAK67507.1 - 2.2e-08 34.2 0.2 1.1e-07 31.9 0.6 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAK67507.1 - 6.3e-05 22.2 0.5 8.8e-05 21.8 0.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAK67507.1 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein MHCassoc_trimer PF08831.10 GAK67507.1 - 0.0028 17.6 0.2 0.0059 16.6 0.2 1.5 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain Epimerase PF01370.21 GAK67507.1 - 0.0031 17.0 0.1 0.15 11.5 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.6 GAK67507.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding protein 3Beta_HSD PF01073.19 GAK67507.1 - 0.021 13.9 0.2 0.03 13.3 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAK67507.1 - 0.17 11.3 0.1 1.9 7.8 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PALP PF00291.25 GAK67508.1 - 2.8e-49 168.1 1.1 3.4e-49 167.8 1.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FA_hydroxylase PF04116.13 GAK67509.1 - 1.6e-19 70.5 11.5 4e-19 69.3 11.5 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Rrn6 PF10214.9 GAK67510.1 - 2e-12 46.5 46.7 8.7e-10 37.8 15.0 5.3 3 2 1 5 5 5 3 RNA polymerase I-specific transcription-initiation factor COS PF18568.1 GAK67510.1 - 0.18 11.7 2.0 0.29 11.1 0.3 2.3 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain Cation_efflux PF01545.21 GAK67511.1 - 9.3e-27 94.1 11.8 1.3e-26 93.6 11.8 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAK67511.1 - 9.2e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Myotub-related PF06602.14 GAK67512.1 - 2.7e-140 467.3 0.0 3.5e-140 466.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 GAK67512.1 - 0.052 13.1 0.1 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DSPc PF00782.20 GAK67512.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain V-SNARE PF05008.15 GAK67513.1 - 2.7e-21 75.7 9.9 3.5e-21 75.3 2.0 2.6 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GAK67513.1 - 5e-17 62.0 6.0 5e-17 62.0 6.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAK67513.1 - 0.00028 20.8 0.4 0.00028 20.8 0.4 1.9 2 0 0 2 2 2 1 Sec20 DUF883 PF05957.13 GAK67513.1 - 0.00067 20.2 8.5 0.094 13.3 0.4 3.1 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 GAK67513.1 - 0.0037 15.3 3.8 0.021 12.8 3.8 1.8 1 1 0 1 1 1 1 Prominin Fusion_gly PF00523.18 GAK67513.1 - 0.013 13.8 0.8 0.015 13.5 0.1 1.6 2 0 0 2 2 2 0 Fusion glycoprotein F0 PTS_IIA PF02255.16 GAK67513.1 - 0.019 15.0 1.7 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2239 PF09998.9 GAK67513.1 - 0.021 14.6 0.1 0.021 14.6 0.1 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) YukC PF10140.9 GAK67513.1 - 0.031 13.1 0.1 0.031 13.1 0.1 1.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC DotU PF09850.9 GAK67513.1 - 0.063 13.0 1.0 0.29 10.8 0.0 2.3 2 1 1 3 3 3 0 Type VI secretion system protein DotU TBCA PF02970.16 GAK67513.1 - 0.1 13.0 7.2 1.4 9.3 1.4 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor A OppC_N PF12911.7 GAK67513.1 - 0.11 12.5 1.2 0.24 11.4 1.2 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Orf78 PF06024.12 GAK67513.1 - 0.11 12.8 0.8 0.27 11.5 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Apolipoprotein PF01442.18 GAK67513.1 - 0.11 12.3 16.5 1.8 8.4 1.7 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain YqjK PF13997.6 GAK67513.1 - 0.19 12.0 3.4 0.15 12.4 0.5 2.1 2 0 0 2 2 2 0 YqjK-like protein YnfE PF17452.2 GAK67513.1 - 0.54 10.6 3.0 3.7 7.9 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized YnfE-like DUF2951 PF11166.8 GAK67513.1 - 0.57 10.4 3.6 0.37 11.0 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-CpG_bind_C PF12269.8 GAK67513.1 - 1.1 9.0 5.0 0.57 9.9 0.4 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF3391 PF11871.8 GAK67513.1 - 1.5 9.3 12.9 6 7.4 4.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF2203 PF09969.9 GAK67513.1 - 1.8 9.3 10.8 0.79 10.5 1.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 GAK67513.1 - 2.1 7.8 11.4 1.2e+02 2.0 11.4 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Sec8_exocyst PF04048.14 GAK67513.1 - 2.5 8.0 7.3 0.83 9.5 0.9 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain FAM76 PF16046.5 GAK67513.1 - 3.7 6.8 5.5 7.1 5.9 0.2 2.1 2 0 0 2 2 2 0 FAM76 protein Abhydrolase_1 PF00561.20 GAK67514.1 - 6.2e-21 75.2 0.0 8.5e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK67514.1 - 5.9e-17 61.7 0.0 1.1e-13 51.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAK67514.1 - 1.3e-14 55.4 0.2 1.3e-14 55.4 0.2 3.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.20 GAK67514.1 - 4.1e-06 26.6 0.0 8.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 GAK67514.1 - 2.4e-05 24.3 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 GAK67514.1 - 0.0001 22.3 0.0 0.047 13.6 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 GAK67514.1 - 0.00023 20.8 0.0 0.00057 19.5 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 GAK67514.1 - 0.00059 19.7 1.8 0.00098 19.0 0.0 2.3 3 0 0 3 3 3 1 Serine hydrolase Ndr PF03096.14 GAK67514.1 - 0.0061 15.3 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 GAK67514.1 - 0.0094 15.4 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAK67514.1 - 0.12 12.1 0.0 2 8.2 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 GAK67514.1 - 0.13 11.6 0.0 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 GAK67514.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 GAK67514.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF3484 PF11983.8 GAK67514.1 - 2.3 9.4 7.4 76 4.5 7.4 2.8 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Fumble PF03630.14 GAK67515.1 - 3.1e-125 417.7 0.0 5.2e-125 417.0 0.0 1.4 1 0 0 1 1 1 1 Fumble MFS_1 PF07690.16 GAK67516.1 - 2.5e-34 118.7 19.2 3.7e-34 118.2 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2830 PF11125.8 GAK67516.1 - 0.16 12.0 0.5 0.57 10.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) DUF4064 PF13273.6 GAK67516.1 - 0.19 12.0 8.4 2.9 8.2 3.7 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF4064) Glyco_hydro_38N PF01074.22 GAK67517.1 - 1e-70 238.4 0.0 1.5e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAK67517.1 - 2.7e-38 132.2 0.0 3.9e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAK67517.1 - 2.3e-25 88.6 0.2 7.6e-25 86.9 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAK67517.1 - 1.1e-08 35.1 0.0 3.4e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 GAK67517.1 - 0.00017 20.9 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Methyltransf_23 PF13489.6 GAK67518.1 - 7.1e-08 32.4 0.0 1.9e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK67518.1 - 2e-05 25.2 0.1 0.00013 22.6 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK67518.1 - 0.00085 19.9 0.2 0.027 15.1 0.1 3.1 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK67518.1 - 0.00094 19.9 0.0 0.0024 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK67518.1 - 0.0016 18.3 0.0 0.0035 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK67518.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAK67518.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF1317 PF07026.11 GAK67518.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) ACOX PF01756.19 GAK67519.1 - 1e-27 96.9 0.4 1e-24 87.1 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAK67519.1 - 2.8e-14 53.8 0.2 6.9e-14 52.5 0.2 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAK67519.1 - 1.1e-09 38.4 0.0 2.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Eaf7 PF07904.13 GAK67520.1 - 3.1e-08 33.9 2.6 3.1e-08 33.9 2.6 3.7 3 1 0 3 3 3 1 Chromatin modification-related protein EAF7 SCO1-SenC PF02630.14 GAK67521.1 - 5.9e-45 152.5 0.0 1e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 GAK67521.1 - 0.098 12.6 0.0 0.78 9.7 0.0 2.1 1 1 0 1 1 1 0 AhpC/TSA family Tcf25 PF04910.14 GAK67522.1 - 1e-108 363.6 0.0 1.3e-108 363.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 YL1 PF05764.13 GAK67522.1 - 0.092 12.9 19.2 0.18 11.9 19.2 1.5 1 0 0 1 1 1 0 YL1 nuclear protein NST1 PF13945.6 GAK67522.1 - 0.6 10.2 9.5 1.4 9.0 9.5 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Pro_isomerase PF00160.21 GAK67523.1 - 2.2e-46 158.0 0.0 3.5e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 GAK67523.1 - 0.00049 20.0 3.3 0.022 14.8 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAK67523.1 - 0.015 15.1 0.2 0.015 15.1 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RdRP PF05183.12 GAK67524.1 - 6.3e-166 553.5 0.0 9.7e-166 552.8 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase MINDY_DUB PF04424.13 GAK67525.1 - 1e-29 103.0 0.0 4.1e-29 101.0 0.0 2.0 2 0 0 2 2 2 1 MINDY deubiquitinase Aminotran_4 PF01063.19 GAK67525.1 - 1.2e-11 44.9 0.0 1.1e-10 41.8 0.0 2.2 1 1 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 GAK67526.1 - 2.3e-17 62.9 0.1 4.2e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK67526.1 - 1.7e-08 34.4 10.0 2.9e-08 33.7 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK67527.1 - 1.1e-21 77.1 0.0 2.4e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK67527.1 - 7.7e-08 32.3 11.1 1.4e-07 31.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5435 PF17503.2 GAK67528.1 - 5.9 6.6 6.8 0.3 10.8 0.2 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5435) SSF PF00474.17 GAK67529.1 - 6.2e-17 61.5 32.0 1.2e-16 60.6 32.0 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Kinesin PF00225.23 GAK67530.1 - 2.5e-106 355.4 0.0 3.6e-106 354.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 GAK67530.1 - 1.5e-42 145.8 4.9 3.3e-34 118.6 0.7 3.5 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 GAK67530.1 - 6.3e-40 137.3 0.0 2.4e-38 132.2 0.0 2.8 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 GAK67530.1 - 1.7e-24 86.4 0.0 3.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 GAK67530.1 - 8.3e-13 48.8 0.0 1.9e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 GAK67530.1 - 2.4e-07 31.1 0.5 6.4e-07 29.7 0.5 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 GAK67530.1 - 1.2e-05 25.6 0.0 0.00015 22.0 0.0 2.7 3 0 0 3 3 3 1 FHA domain PH_9 PF15410.6 GAK67530.1 - 0.05 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PPR_2 PF13041.6 GAK67532.1 - 7.4e-48 160.5 1.1 1.9e-08 34.4 0.0 12.0 9 3 5 14 14 14 9 PPR repeat family PPR PF01535.20 GAK67532.1 - 9.6e-32 107.0 12.0 0.00029 20.9 0.0 14.1 17 0 0 17 17 15 6 PPR repeat PPR_1 PF12854.7 GAK67532.1 - 5.7e-21 73.9 3.2 9.8e-05 22.0 0.0 8.3 9 0 0 9 9 9 4 PPR repeat PPR_3 PF13812.6 GAK67532.1 - 9.4e-21 73.7 0.0 1.8e-07 31.1 0.0 8.6 7 2 2 9 9 9 3 Pentatricopeptide repeat domain PPR_long PF17177.4 GAK67532.1 - 3.1e-16 59.4 2.9 6.3e-11 42.0 0.0 5.7 4 2 1 6 6 6 1 Pentacotripeptide-repeat region of PRORP Methyltransf_11 PF08241.12 GAK67532.1 - 5.3e-14 52.6 0.0 2.4e-13 50.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK67532.1 - 1.8e-12 47.8 0.2 1.5e-11 44.8 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK67532.1 - 4.8e-10 39.5 0.0 1.2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK67532.1 - 6.8e-10 39.6 0.0 2.6e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAK67532.1 - 5.5e-07 29.2 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAK67532.1 - 7.3e-07 29.1 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPR_7 PF13176.6 GAK67532.1 - 0.0055 16.7 0.0 6 7.1 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat DJ-1_PfpI PF01965.24 GAK67532.1 - 0.011 15.5 0.0 0.042 13.6 0.0 2.0 2 0 0 2 2 2 0 DJ-1/PfpI family MAJIN PF15077.6 GAK67532.1 - 0.047 13.5 0.3 0.096 12.5 0.3 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Med13_C PF06333.12 GAK67533.1 - 3.4e-12 46.3 0.2 3.4e-12 46.3 0.2 5.9 6 1 1 7 7 7 2 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 GAK67533.1 - 1 9.1 0.0 1 9.1 0.0 3.1 4 1 0 4 4 4 0 MID domain of medPIWI Glyco_hydro_cc PF11790.8 GAK67535.1 - 4.1e-61 206.6 7.8 5.3e-61 206.2 7.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.17 GAK67535.1 - 0.002 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_53 PF07745.13 GAK67535.1 - 0.0025 16.8 2.1 0.0026 16.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 Mur_ligase_M PF08245.12 GAK67536.1 - 0.037 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Mur ligase middle domain DltD PF04914.12 GAK67536.1 - 0.79 9.0 5.5 1.3 8.3 5.5 1.2 1 0 0 1 1 1 0 DltD protein AAA_11 PF13086.6 GAK67536.1 - 3.4 7.4 9.1 17 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Asp PF00026.23 GAK67537.1 - 4.9e-08 32.8 0.1 0.034 13.6 0.0 3.3 3 1 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK67537.1 - 0.0031 17.8 0.3 0.023 14.9 0.0 2.2 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAK67537.1 - 0.061 14.0 1.2 6.1 7.6 0.2 3.1 2 1 0 2 2 2 0 Aspartyl protease ADH_N PF08240.12 GAK67538.1 - 1.2e-24 86.3 2.3 1.2e-24 86.3 2.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAK67538.1 - 3.5e-22 78.8 0.4 6.8e-22 77.8 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAK67538.1 - 0.0011 18.3 1.0 0.0019 17.5 1.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAK67538.1 - 0.019 14.3 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAK67538.1 - 0.14 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SNF2_N PF00176.23 GAK67539.1 - 5.6e-62 209.5 0.0 3.3e-60 203.7 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAK67539.1 - 2.3e-18 66.6 0.0 1.2e-17 64.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PIG-X PF08320.12 GAK67541.1 - 7.2e-24 84.9 0.9 2.6e-23 83.1 0.9 1.7 1 1 0 1 1 1 1 PIG-X / PBN1 Ric8 PF10165.9 GAK67542.1 - 6.3e-133 444.2 0.0 8.8e-133 443.7 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn PIP5K PF01504.18 GAK67543.1 - 8.8e-35 120.3 0.0 3.6e-34 118.3 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase XPG_N PF00752.17 GAK67543.1 - 0.16 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain NOA36 PF06524.12 GAK67543.1 - 1.9 7.7 4.3 4.3 6.6 4.3 1.5 1 0 0 1 1 1 0 NOA36 protein CBFD_NFYB_HMF PF00808.23 GAK67544.1 - 1.9e-25 88.9 0.4 2.6e-25 88.5 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAK67544.1 - 0.00014 22.3 0.6 0.00025 21.4 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAK67544.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 GAK67544.1 - 0.066 13.2 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Gar1 PF04410.14 GAK67544.1 - 0.33 10.7 1.9 0.43 10.4 1.7 1.4 1 1 0 1 1 1 0 Gar1/Naf1 RNA binding region SNO PF01174.19 GAK67545.1 - 1.9e-52 177.8 0.0 2.2e-42 145.1 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAK67545.1 - 1.5e-10 41.0 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 GAK67545.1 - 5.5e-05 22.9 0.0 8.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 GAK67545.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 GAK67545.1 - 0.0086 15.9 0.1 0.21 11.3 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I BPL_N PF09825.9 GAK67545.1 - 0.12 11.4 0.0 1.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal TPR_2 PF07719.17 GAK67546.1 - 2.8e-08 33.2 31.7 0.21 11.8 0.0 10.0 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAK67546.1 - 1.9e-05 24.5 12.1 21 5.6 0.0 8.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAK67546.1 - 0.00042 20.0 18.4 0.055 13.3 0.9 6.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAK67546.1 - 0.012 15.3 0.3 0.012 15.3 0.3 6.9 8 0 0 8 8 8 0 TPR repeat TPR_16 PF13432.6 GAK67546.1 - 0.015 15.9 0.2 0.015 15.9 0.2 11.3 10 2 0 10 10 10 0 Tetratricopeptide repeat MCU PF04678.13 GAK67546.1 - 3.8 7.6 5.7 8.4 6.5 4.2 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter TPR_6 PF13174.6 GAK67546.1 - 6.9 7.5 27.7 0.66 10.7 0.1 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat DHBP_synthase PF00926.19 GAK67547.1 - 2.1e-81 272.0 0.0 2.5e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Cpn60_TCP1 PF00118.24 GAK67548.1 - 4.8e-147 490.5 13.8 5.5e-147 490.3 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 GAK67548.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Proteasome PF00227.26 GAK67549.1 - 8.7e-48 162.3 2.5 3.8e-45 153.7 0.4 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 GAK67549.1 - 7e-15 54.4 0.4 1.6e-14 53.2 0.4 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nop PF01798.18 GAK67550.1 - 1.9e-84 282.7 0.1 1.9e-84 282.7 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAK67550.1 - 3.7e-15 56.1 0.2 3.7e-15 56.1 0.2 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF4423 PF14394.6 GAK67550.1 - 0.42 10.3 7.0 2.4 7.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4423) SH3_1 PF00018.28 GAK67551.1 - 2.2e-10 40.0 0.3 3.5e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAK67551.1 - 0.00024 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAK67551.1 - 0.0027 17.5 0.2 0.0048 16.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain Forkhead PF00250.18 GAK67552.1 - 3.6e-26 91.2 0.1 6.7e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain VTC PF09359.10 GAK67554.1 - 2.5e-99 332.2 0.0 2.5e-99 332.2 0.0 1.9 3 0 0 3 3 3 1 VTC domain SPX PF03105.19 GAK67554.1 - 1.1e-18 68.3 34.7 1.1e-12 48.6 5.9 4.5 2 2 1 3 3 3 2 SPX domain DUF202 PF02656.15 GAK67554.1 - 9.5e-12 45.2 0.4 7.3e-11 42.4 0.8 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF202) DUF1319 PF07028.11 GAK67554.1 - 0.48 10.7 2.9 0.62 10.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) DUF5482 PF17579.2 GAK67554.1 - 0.66 9.8 4.1 2.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5482) SDA1 PF05285.12 GAK67555.1 - 2.1e-94 316.8 41.8 2.1e-94 316.8 41.8 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GAK67555.1 - 1.6e-18 66.8 0.1 4.4e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain DUF733 PF05306.11 GAK67555.1 - 0.36 11.2 11.0 1.1 9.7 4.5 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF733) DEAD PF00270.29 GAK67556.1 - 5.6e-40 137.0 0.0 1e-39 136.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK67556.1 - 1.1e-17 64.4 0.0 2.9e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAK67556.1 - 1.9e-15 56.8 0.4 4.8e-15 55.5 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAK67556.1 - 2.5e-06 27.6 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit STAT_alpha PF01017.20 GAK67557.1 - 0.013 15.4 0.2 0.022 14.7 0.2 1.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain CPSase_L_D2 PF02786.17 GAK67558.1 - 6.5e-106 352.5 0.0 3.8e-82 274.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 GAK67558.1 - 1.7e-39 134.9 0.5 5.6e-39 133.3 0.5 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 GAK67558.1 - 1.7e-17 63.5 0.0 7e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAK67558.1 - 3.4e-13 49.6 0.1 2.6e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAK67558.1 - 6.2e-12 45.4 0.0 0.0002 21.1 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 GAK67558.1 - 2.2e-06 27.8 0.0 0.00053 20.1 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 GAK67558.1 - 2.4e-06 27.2 0.6 0.0078 15.7 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 GAK67558.1 - 2.5e-06 27.2 0.0 0.015 14.9 0.0 2.9 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 GAK67558.1 - 0.027 14.0 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain MGS PF02142.22 GAK67558.1 - 0.031 14.4 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 1 0 MGS-like domain GARS_A PF01071.19 GAK67558.1 - 0.035 13.9 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.21 GAK67558.1 - 0.038 13.5 0.0 0.68 9.3 0.0 2.8 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Peptidase_M17_N PF02789.17 GAK67558.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.5 3 0 0 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain Sigma70_r4_2 PF08281.12 GAK67558.1 - 0.31 10.8 1.5 0.39 10.4 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HLH PF00010.26 GAK67559.1 - 9.7e-15 54.3 0.2 1.8e-14 53.4 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyoxalase PF00903.25 GAK67559.1 - 0.033 14.4 0.7 0.14 12.4 0.0 2.2 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2433 PF10360.9 GAK67561.1 - 3.7e-44 149.8 0.3 8.8e-44 148.6 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 GAK67561.1 - 0.00016 21.4 0.0 0.039 13.8 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 GAK67561.1 - 0.025 15.1 0.0 0.14 12.6 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAK67561.1 - 0.066 13.4 0.2 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Cgr1 PF03879.14 GAK67562.1 - 8.4e-20 71.2 23.7 9.3e-20 71.0 23.7 1.0 1 0 0 1 1 1 1 Cgr1 family Auts2 PF15336.6 GAK67562.1 - 0.31 11.1 6.7 0.36 10.9 6.7 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Dynamin_N PF00350.23 GAK67562.1 - 0.56 10.3 4.0 0.67 10.0 4.0 1.1 1 0 0 1 1 1 0 Dynamin family SID-1_RNA_chan PF13965.6 GAK67562.1 - 5.4 5.3 4.5 6 5.2 4.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 GAK67562.1 - 9.2 6.0 14.8 10 5.8 14.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GTP_EFTU PF00009.27 GAK67563.1 - 2.7e-34 118.4 1.1 8.9e-34 116.7 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAK67563.1 - 6.1e-17 61.7 0.2 2.7e-16 59.6 0.0 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 GAK67563.1 - 4.8e-13 49.3 8.8 8.4e-10 38.9 0.2 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAK67563.1 - 1.9e-06 27.9 0.2 8.3e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 GAK67563.1 - 0.0002 21.5 0.0 0.00068 19.8 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 GAK67563.1 - 0.0075 16.1 0.1 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ras PF00071.22 GAK67563.1 - 0.11 12.1 0.2 0.44 10.1 0.0 2.1 2 1 0 2 2 2 0 Ras family MCPVI PF02993.14 GAK67566.1 - 0.00084 19.2 0.9 0.0011 18.9 0.9 1.2 1 0 0 1 1 1 1 Minor capsid protein VI Ribosomal_L2_C PF03947.18 GAK67567.1 - 8.1e-46 155.3 2.3 1.4e-45 154.6 2.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAK67567.1 - 4.5e-13 49.0 0.2 1.1e-12 47.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Rad10 PF03834.14 GAK67568.1 - 7.9e-49 164.4 0.5 1.1e-48 163.9 0.5 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 GAK67568.1 - 1.4e-08 35.2 0.2 4.7e-07 30.3 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain SLT PF01464.20 GAK67569.1 - 2e-16 59.7 0.0 2e-16 59.7 0.0 2.5 2 1 1 3 3 3 1 Transglycosylase SLT domain Macoilin PF09726.9 GAK67569.1 - 0.011 14.3 30.0 0.014 14.0 30.0 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 GAK67569.1 - 0.047 10.8 21.6 0.056 10.6 21.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 GAK67569.1 - 0.051 13.5 26.3 0.07 13.0 26.3 1.3 1 0 0 1 1 1 0 SPX domain Mem_trans PF03547.18 GAK67569.1 - 0.23 9.8 3.9 0.32 9.3 3.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Presenilin PF01080.17 GAK67569.1 - 0.31 9.7 18.0 0.53 9.0 18.0 1.4 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 GAK67569.1 - 0.54 8.9 13.8 0.74 8.4 13.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PNISR PF15996.5 GAK67569.1 - 4.1 7.6 17.2 7 6.9 17.2 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR FAM220 PF15487.6 GAK67569.1 - 8.9 5.9 22.6 13 5.3 22.6 1.3 1 0 0 1 1 1 0 FAM220 family RR_TM4-6 PF06459.12 GAK67569.1 - 9.9 5.9 16.7 14 5.4 16.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Actin PF00022.19 GAK67570.1 - 1.4e-147 491.6 0.0 3.3e-147 490.4 0.0 1.6 1 1 0 1 1 1 1 Actin His_biosynth PF00977.21 GAK67570.1 - 4.5e-35 121.2 0.0 1e-34 120.0 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein GST_N PF02798.20 GAK67570.1 - 1.7e-12 47.5 0.0 3.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAK67570.1 - 5.9e-07 29.8 0.1 1.5e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK67570.1 - 2.8e-05 24.3 0.0 6.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAK67570.1 - 0.026 14.7 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thioredoxin PF00085.20 GAK67571.1 - 1.9e-40 137.0 0.3 4.8e-22 77.9 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 GAK67571.1 - 7.1e-13 48.9 0.0 1.2e-07 31.8 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAK67571.1 - 3e-09 37.3 0.0 0.0004 20.8 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAK67571.1 - 0.00021 21.5 0.1 0.021 15.2 0.0 3.4 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAK67571.1 - 0.00032 20.7 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_7 PF13899.6 GAK67571.1 - 0.00033 20.8 0.1 0.0075 16.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 GAK67571.1 - 0.00037 20.2 0.4 0.71 9.6 0.1 2.7 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 GAK67571.1 - 0.0069 16.3 0.0 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_4 PF13462.6 GAK67571.1 - 0.012 15.8 9.3 0.56 10.3 0.1 3.6 3 1 0 4 4 4 0 Thioredoxin TraF PF13728.6 GAK67571.1 - 0.079 12.8 0.0 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 GAK67571.1 - 0.11 11.9 0.2 16 4.7 0.0 3.1 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 GAK67571.1 - 0.24 11.7 2.0 0.82 9.9 0.1 2.5 2 0 0 2 2 2 0 Glutaredoxin RICTOR_N PF14664.6 GAK67572.1 - 1.7e-103 346.5 1.2 3.1e-103 345.6 0.5 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 GAK67572.1 - 9e-39 131.4 0.6 6.6e-35 119.0 0.1 4.3 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 GAK67572.1 - 1e-33 116.0 0.2 6.6e-33 113.4 0.1 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 GAK67572.1 - 3.4e-30 104.1 2.0 1.1e-28 99.2 0.1 4.0 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 GAK67572.1 - 6.9e-15 54.9 1.8 6.9e-15 54.9 1.8 2.3 2 0 0 2 2 2 1 Hr1 repeat Mucin15 PF15672.5 GAK67572.1 - 0.25 10.8 7.2 0.035 13.6 2.3 2.0 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 HEAT PF02985.22 GAK67572.1 - 0.56 10.6 8.6 22 5.6 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 GAK67572.1 - 2.3 8.8 10.9 48 4.6 2.7 5.5 5 0 0 5 5 5 0 HEAT-like repeat THOC7 PF05615.13 GAK67572.1 - 7 6.9 12.4 1.4 9.2 0.6 3.1 3 0 0 3 3 3 0 Tho complex subunit 7 AAA PF00004.29 GAK67574.1 - 0.00039 20.9 0.0 0.0011 19.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAK67574.1 - 0.036 14.0 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 GAK67574.1 - 0.086 13.1 0.2 0.77 10.0 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAK67574.1 - 0.22 11.9 0.0 0.22 11.9 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain CPBP PF02517.16 GAK67575.1 - 4.6e-09 36.5 1.7 4.6e-09 36.5 1.7 1.9 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Cyclin_N PF00134.23 GAK67576.1 - 1.9e-13 50.3 3.0 3.1e-13 49.6 0.5 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 GAK67576.1 - 0.0075 16.6 0.5 0.0075 16.6 0.5 1.9 2 1 0 2 2 2 1 Cyclin C-terminal domain Cyclin_C PF02984.19 GAK67576.1 - 0.012 15.7 2.7 2.5 8.2 0.2 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.19 GAK67576.1 - 0.024 14.7 3.3 0.026 14.6 0.6 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Spt4 PF06093.13 GAK67577.1 - 1.4e-32 111.6 0.0 1.7e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger MIF4G_like PF09088.11 GAK67578.1 - 3.6e-75 251.9 0.0 7.7e-75 250.9 0.0 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 GAK67578.1 - 5.1e-67 226.2 0.0 8.4e-67 225.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G like Erythrovirus_X PF06795.11 GAK67578.1 - 0.033 14.5 0.1 0.076 13.3 0.1 1.6 1 0 0 1 1 1 0 Erythrovirus X protein DUF3546 PF12066.8 GAK67579.1 - 4.6e-15 55.8 7.0 7.7e-15 55.0 1.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 GAK67579.1 - 8.4e-13 49.1 0.0 1.7e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 LIM_bind PF01803.16 GAK67580.1 - 4.1e-44 150.9 0.0 4.1e-44 150.9 0.0 6.7 3 2 1 4 4 4 1 LIM-domain binding protein Adeno_E3_14_5 PF04834.12 GAK67580.1 - 4.3 7.9 6.0 8.4 7.0 4.9 2.1 1 1 0 1 1 1 0 Early E3 14.5 kDa protein TAF4 PF05236.14 GAK67581.1 - 1.1e-36 127.0 2.2 2e-36 126.2 2.2 1.4 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Got1 PF04178.12 GAK67581.1 - 1.1e-17 64.5 14.2 1.7e-17 63.9 14.2 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family ALG3 PF05208.13 GAK67582.1 - 3.6e-128 428.0 14.9 3.6e-128 428.0 14.9 2.1 3 0 0 3 3 3 1 ALG3 protein Gaa1 PF04114.14 GAK67582.1 - 1.1e-81 275.4 4.6 2.1e-80 271.2 0.0 2.5 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component Peptidase_M28 PF04389.17 GAK67582.1 - 0.093 12.4 0.4 0.65 9.7 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M28 Ecm33 PF12454.8 GAK67582.1 - 0.2 11.8 0.8 0.94 9.7 0.8 2.2 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TIP49 PF06068.13 GAK67583.1 - 2.7e-162 539.9 0.1 5.9e-162 538.8 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAK67583.1 - 6.1e-21 74.3 0.1 1.5e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAK67583.1 - 1.4e-10 41.7 0.8 2.1e-06 28.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAK67583.1 - 9.6e-09 35.2 0.0 1.6e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAK67583.1 - 1.7e-06 28.3 0.1 0.016 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GAK67583.1 - 0.00034 20.6 0.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 GAK67583.1 - 0.00066 20.0 2.9 0.037 14.4 2.9 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAK67583.1 - 0.00082 19.8 0.0 0.0063 16.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 GAK67583.1 - 0.0032 17.7 0.1 0.0075 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAK67583.1 - 0.0053 16.5 0.1 2.9 7.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 GAK67583.1 - 0.0076 15.8 0.1 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAK67583.1 - 0.009 15.4 0.1 0.53 9.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 GAK67583.1 - 0.011 15.0 0.4 0.025 13.9 0.4 1.5 1 0 0 1 1 1 0 Zeta toxin DnaB_C PF03796.15 GAK67583.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 GAK67583.1 - 0.051 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UBA_2 PF08587.11 GAK67583.1 - 0.059 13.5 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF2075 PF09848.9 GAK67583.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 GAK67583.1 - 0.22 11.0 0.2 0.82 9.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Peroxin-3 PF04882.12 GAK67584.1 - 7e-144 480.3 0.2 6.1e-143 477.2 0.2 1.9 1 1 0 1 1 1 1 Peroxin-3 PAM2 PF07145.15 GAK67584.1 - 0.017 14.8 0.5 0.053 13.2 0.5 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region ACBP PF00887.19 GAK67585.1 - 3.8e-24 84.7 0.0 7.7e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein ribosomal_L24 PF17136.4 GAK67586.1 - 0.022 15.1 0.0 0.056 13.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 DUF2502 PF10697.9 GAK67586.1 - 0.14 12.5 4.1 0.11 12.9 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) KOW PF00467.29 GAK67586.1 - 0.16 12.0 1.9 18 5.5 0.0 3.1 3 0 0 3 3 3 0 KOW motif SH3_9 PF14604.6 GAK67587.1 - 2.6e-08 33.6 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAK67587.1 - 6.4e-07 28.9 0.0 1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAK67587.1 - 0.00066 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 GAK67587.1 - 1.3 8.9 15.0 1.8 8.4 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MoCF_biosynth PF00994.24 GAK67588.1 - 9.1e-56 187.5 0.7 7.3e-29 100.3 0.1 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 GAK67588.1 - 4.1e-34 117.6 1.1 6.9e-34 116.9 1.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 GAK67588.1 - 1.1e-10 41.5 1.6 2.8e-10 40.2 0.1 2.6 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) DUF2946 PF11162.8 GAK67588.1 - 0.047 14.4 5.2 0.18 12.5 5.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Ank_2 PF12796.7 GAK67590.1 - 3.2e-21 75.7 0.0 2.4e-08 34.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK67590.1 - 1.5e-18 66.9 1.9 9.8e-11 42.0 0.2 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAK67590.1 - 8.4e-14 51.3 0.0 5.9e-05 23.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAK67590.1 - 2.9e-12 46.6 0.1 4.5e-06 26.8 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAK67590.1 - 5.4e-12 44.8 0.2 0.001 19.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat MRP-S34 PF16053.5 GAK67590.1 - 4.4e-08 32.9 0.2 5.5e-05 22.8 0.1 2.5 1 1 1 2 2 2 2 Mitochondrial 28S ribosomal protein S34 KilA-N PF04383.13 GAK67590.1 - 4.4e-06 26.5 0.1 4.7e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain UPF0300 PF08594.10 GAK67590.1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) DHR10 PF18595.1 GAK67590.1 - 2.8 8.0 8.5 18 5.4 3.4 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain EMG1 PF03587.14 GAK67591.1 - 6.3e-78 260.9 0.0 1.5e-77 259.6 0.0 1.6 2 0 0 2 2 2 1 EMG1/NEP1 methyltransferase DUF3498 PF12004.8 GAK67591.1 - 0.064 12.4 0.0 0.064 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) NUDIX PF00293.28 GAK67592.1 - 6.4e-15 55.4 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 GAK67592.1 - 1.7e-11 44.7 0.1 4.3e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain 7TM_GPCR_Str PF10326.9 GAK67592.1 - 0.19 11.0 0.0 2.2 7.5 0.0 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str RRM_1 PF00076.22 GAK67593.1 - 2.7e-39 132.8 0.0 8.3e-21 73.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK67593.1 - 4.6e-07 29.9 0.0 0.00031 20.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 GAK67593.1 - 0.0062 16.6 4.5 0.25 11.4 0.0 2.9 2 1 1 3 3 3 2 RNA binding motif RRM_5 PF13893.6 GAK67593.1 - 0.019 14.6 0.0 0.091 12.4 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 GAK67593.1 - 0.72 8.3 30.5 0.95 7.9 30.5 1.1 1 0 0 1 1 1 0 Macoilin family 2-Hacid_dh_C PF02826.19 GAK67595.1 - 6.5e-26 90.8 0.1 9.5e-25 87.0 0.1 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 GAK67595.1 - 0.034 13.5 0.2 0.055 12.8 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 GAK67595.1 - 0.088 12.1 1.9 2.3 7.4 0.0 2.8 1 1 2 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_18 PF00704.28 GAK67596.1 - 1.4e-59 202.3 0.1 1.8e-59 202.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ThiF PF00899.21 GAK67598.1 - 4.6e-98 327.4 0.0 1.7e-67 227.4 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAK67598.1 - 1.3e-88 297.1 0.0 2e-88 296.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 GAK67598.1 - 6.8e-32 109.5 0.3 1.5e-31 108.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 GAK67598.1 - 1e-31 109.4 0.1 2e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GAK67598.1 - 3.2e-26 91.3 0.5 7.5e-26 90.1 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle adh_short_C2 PF13561.6 GAK67599.1 - 8.6e-43 146.6 0.1 1.6e-42 145.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DSPn PF14671.6 GAK67599.1 - 2.8e-36 125.1 0.0 3.3e-35 121.6 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half adh_short PF00106.25 GAK67599.1 - 6.7e-30 104.0 0.2 1.2e-29 103.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DSPc PF00782.20 GAK67599.1 - 6.3e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAK67599.1 - 0.00078 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAK67599.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Acyl-CoA_dh_1 PF00441.24 GAK67600.1 - 3e-44 150.8 3.8 3e-44 150.8 3.8 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAK67600.1 - 1.1e-26 93.8 1.0 4.5e-26 91.7 0.0 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAK67600.1 - 1.6e-22 79.5 0.1 3e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAK67600.1 - 6.9e-22 78.2 1.1 6.9e-22 78.2 1.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Snf7 PF03357.21 GAK67600.1 - 0.0029 17.2 1.4 0.0061 16.2 1.4 1.5 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.20 GAK67600.1 - 0.057 13.4 0.2 3.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit tRNA-synt_2b PF00587.25 GAK67601.1 - 6.6e-31 107.7 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAK67601.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain RRM_1 PF00076.22 GAK67602.1 - 2.7e-15 56.0 0.0 7e-06 25.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AF-4 PF05110.13 GAK67602.1 - 0.0017 16.5 22.9 0.0017 16.5 22.9 3.0 3 0 0 3 3 3 1 AF-4 proto-oncoprotein Zip PF02535.22 GAK67602.1 - 2.5 7.2 14.1 3 7.0 6.8 2.4 2 1 0 2 2 2 0 ZIP Zinc transporter MAM33 PF02330.16 GAK67603.1 - 1.6e-65 221.0 0.1 1.9e-65 220.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein PITH PF06201.13 GAK67604.1 - 5.1e-30 104.7 0.0 1e-29 103.7 0.0 1.5 1 0 0 1 1 1 1 PITH domain CENP-T_C PF15511.6 GAK67604.1 - 7.3e-09 35.7 0.5 7.3e-09 35.7 0.5 2.0 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Sec63 PF02889.16 GAK67605.1 - 5.9e-16 58.4 0.0 9.6e-15 54.4 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 GAK67605.1 - 1.9e-15 56.7 1.2 4.5e-15 55.5 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain DDOST_48kD PF03345.14 GAK67605.1 - 0.024 13.5 0.0 4.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta Abhydro_lipase PF04083.16 GAK67606.1 - 2.6e-16 58.9 0.0 5.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAK67606.1 - 4e-09 36.5 0.1 9.7e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK67606.1 - 0.021 14.1 0.0 0.067 12.5 0.1 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PMT PF02366.18 GAK67607.1 - 1.2e-77 260.8 11.8 1.2e-77 260.8 11.8 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAK67607.1 - 1.9e-66 223.4 5.4 1.9e-66 223.4 5.4 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAK67607.1 - 1.4e-40 139.2 0.3 3e-40 138.1 0.3 1.6 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.6 GAK67607.1 - 0.00058 20.1 10.4 0.00058 20.1 10.4 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1180 PF06679.12 GAK67607.1 - 1.2 9.5 8.2 0.054 13.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SNARE PF05739.19 GAK67608.1 - 1.5e-12 47.3 0.4 1.5e-12 47.3 0.4 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 GAK67608.1 - 7.8e-06 25.7 2.5 7.8e-06 25.7 2.5 2.5 3 0 0 3 3 3 2 Syntaxin MCPsignal PF00015.21 GAK67608.1 - 0.067 13.0 2.8 0.11 12.3 0.4 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 GAK67608.1 - 0.72 10.2 4.6 1.5 9.2 1.0 2.7 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 GAK67608.1 - 1.4 9.4 4.1 0.57 10.6 0.4 2.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 GAK67608.1 - 9.8 6.6 8.9 0.67 10.4 2.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4211 PF13926.6 GAK67609.1 - 3.7e-10 40.0 0.1 4.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Macoilin PF09726.9 GAK67609.1 - 7.4 5.0 10.2 3.4 6.1 5.5 2.2 2 0 0 2 2 2 0 Macoilin family S36_mt PF10937.8 GAK67610.1 - 3.9e-08 34.9 5.0 8e-08 33.9 5.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial NDUF_B7 PF05676.13 GAK67611.1 - 5.4e-29 99.7 2.2 6.5e-29 99.4 2.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 GAK67611.1 - 8.6e-05 22.5 0.9 0.00012 22.0 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CGI-121 PF08617.10 GAK67612.1 - 9.4e-49 165.7 0.0 1.1e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Alpha_Helical PF18489.1 GAK67612.1 - 0.047 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha helical domain DUF2834 PF11196.8 GAK67613.1 - 1.2e-08 35.2 15.2 0.001 19.4 2.1 4.3 4 0 0 4 4 4 4 Protein of unknown function (DUF2834) PMI_typeI PF01238.21 GAK67614.1 - 1e-109 367.2 0.0 1.2e-109 367.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 GAK67614.1 - 3.5e-06 26.6 0.0 0.00065 19.4 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.7 GAK67614.1 - 0.0017 18.1 0.1 0.011 15.5 0.1 2.2 2 0 0 2 2 2 1 Cupin Cupin_3 PF05899.12 GAK67614.1 - 0.04 13.6 0.3 0.083 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAK67614.1 - 0.21 11.5 0.1 46 3.9 0.0 3.4 4 0 0 4 4 4 0 AraC-like ligand binding domain XRN_M PF17846.1 GAK67616.1 - 9.6e-149 496.1 2.4 4e-144 480.9 2.4 2.8 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 GAK67616.1 - 1.6e-100 335.6 0.9 2.9e-100 334.7 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 GAK67616.1 - 0.00064 19.7 0.8 0.0015 18.6 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GAK67616.1 - 0.045 13.6 0.6 0.081 12.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Vfa1 PF08432.10 GAK67617.1 - 2.6e-37 128.9 3.9 3.9e-37 128.3 3.9 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 LIAS_N PF16881.5 GAK67617.1 - 0.014 15.8 0.9 0.13 12.7 0.4 2.2 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Enolase_N PF03952.16 GAK67617.1 - 0.04 14.1 1.0 0.079 13.1 0.2 1.8 2 0 0 2 2 2 0 Enolase, N-terminal domain AMP-binding PF00501.28 GAK67619.1 - 2e-85 286.9 0.0 2.6e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK67619.1 - 3.9e-10 40.6 0.5 9.4e-10 39.3 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HicA_toxin PF07927.12 GAK67619.1 - 0.085 12.9 0.3 0.33 11.0 0.3 2.0 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Elong-fact-P_C PF09285.11 GAK67619.1 - 0.086 12.6 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Elongation factor P, C-terminal Translin PF01997.16 GAK67622.1 - 9.2e-53 179.3 1.3 3.9e-52 177.2 0.1 1.9 2 0 0 2 2 2 1 Translin family DinB PF05163.12 GAK67623.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 DinB family HMG_box PF00505.19 GAK67625.1 - 3.6e-15 56.1 2.1 8.4e-15 54.9 2.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAK67625.1 - 2.4e-11 44.0 1.3 4.5e-11 43.2 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 GAK67625.1 - 0.0011 18.9 0.1 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 CHDNT (NUC034) domain PhageMin_Tail PF10145.9 GAK67625.1 - 0.013 15.3 0.6 0.028 14.3 0.6 1.5 1 1 0 1 1 1 0 Phage-related minor tail protein MCC-bdg_PDZ PF10506.9 GAK67625.1 - 0.021 14.8 0.1 0.048 13.7 0.1 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome zf-CCCH_4 PF18044.1 GAK67626.1 - 0.0006 19.6 7.6 0.001 18.8 7.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAK67626.1 - 0.0072 16.3 8.5 0.012 15.6 8.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAK67626.1 - 0.0096 15.8 5.8 0.02 14.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAK67626.1 - 0.017 15.8 0.7 0.017 15.8 0.7 2.8 2 0 0 2 2 2 0 Torus domain Med26 PF08711.11 GAK67626.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain zf-CCCH_2 PF14608.6 GAK67626.1 - 0.31 11.6 8.0 0.55 10.8 8.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 GAK67626.1 - 3.8 7.8 9.4 0.045 14.0 1.1 2.0 2 0 0 2 2 2 0 Zinc-finger containing family dsDNA_bind PF01984.20 GAK67626.1 - 6 7.2 17.7 1.4e+02 2.8 0.0 2.9 2 0 0 2 2 2 0 Double-stranded DNA-binding domain ArAE_2_N PF10337.9 GAK67627.1 - 3e-61 207.9 0.2 3e-61 207.9 0.2 2.8 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 GAK67627.1 - 9.4e-23 81.2 0.4 1e-11 45.2 0.0 3.4 3 0 0 3 3 3 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 GAK67627.1 - 1.2e-08 35.1 20.7 1.2e-08 35.1 20.7 4.0 2 2 2 5 5 5 1 Fusaric acid resistance protein-like ALMT PF11744.8 GAK67627.1 - 0.1 11.4 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Pkinase PF00069.25 GAK67628.1 - 2.7e-71 240.0 0.0 3.9e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_3 PF07859.13 GAK67628.1 - 3.4e-48 164.3 0.6 3.9e-47 160.8 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.17 GAK67628.1 - 6.6e-35 120.6 0.0 9.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Say1_Mug180 PF10340.9 GAK67628.1 - 2.5e-12 46.3 0.0 7.3e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase YrbL-PhoP_reg PF10707.9 GAK67628.1 - 5.2e-05 22.9 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 GAK67628.1 - 0.0083 15.5 0.5 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAK67628.1 - 0.032 13.5 0.0 0.52 9.6 0.0 2.4 2 0 0 2 2 2 0 Kinase-like CCDC106 PF15794.5 GAK67628.1 - 5.5 6.6 9.4 0.82 9.3 0.8 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Na_H_Exchanger PF00999.21 GAK67629.1 - 1.8e-26 92.9 31.7 1.9e-13 50.0 5.6 2.3 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family RTA1 PF04479.13 GAK67630.1 - 2.4e-51 174.3 6.1 2.8e-51 174.1 6.1 1.1 1 0 0 1 1 1 1 RTA1 like protein URO-D PF01208.17 GAK67631.1 - 2.7e-138 460.9 0.0 3.1e-138 460.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF4965 PF16335.5 GAK67632.1 - 2.6e-71 238.9 0.1 4.8e-71 238.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 GAK67632.1 - 5e-65 219.0 1.7 7.9e-65 218.3 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 GAK67632.1 - 3.9e-50 170.7 4.2 3.9e-50 170.7 4.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 GAK67632.1 - 0.065 12.8 0.6 6.1 6.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4964) RNA_pol_Rpb1_1 PF04997.12 GAK67633.1 - 1.2e-85 287.6 0.1 1.8e-85 287.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAK67633.1 - 2.2e-82 276.5 0.6 3.1e-82 276.0 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAK67633.1 - 3.9e-72 241.9 0.0 7.2e-72 241.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 FAA_hydrolase PF01557.18 GAK67633.1 - 1.7e-52 178.3 0.0 3e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RNA_pol_Rpb1_3 PF04983.18 GAK67633.1 - 1.2e-36 126.0 0.0 4.6e-36 124.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAK67633.1 - 1e-30 105.8 0.0 2.2e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2225 PF09986.9 GAK67633.1 - 0.066 12.9 0.5 0.12 12.0 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 GAK67633.1 - 0.14 13.0 1.1 0.32 11.8 1.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family zf-tcix PF14952.6 GAK67633.1 - 0.18 11.4 0.5 0.56 9.9 0.5 1.8 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding UNC45-central PF11701.8 GAK67634.1 - 2.3e-11 43.9 1.3 1.6e-10 41.1 1.3 2.6 1 1 0 1 1 1 1 Myosin-binding striated muscle assembly central DUF305 PF03713.13 GAK67634.1 - 0.26 11.4 2.8 0.34 11.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF305) Bac_rhamnosid_C PF17390.2 GAK67635.1 - 1.3e-09 37.7 0.1 2.4e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 GAK67635.1 - 0.0062 15.8 1.4 8.4 5.5 0.0 3.2 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Pyr_redox_2 PF07992.14 GAK67636.1 - 7.4e-29 100.9 0.0 9.7e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK67636.1 - 2.4e-10 40.9 0.0 8.8e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK67636.1 - 0.039 13.2 0.0 0.62 9.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 GAK67637.1 - 1.7e-19 70.0 38.4 2.9e-17 62.6 13.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAK67637.1 - 9.7e-08 31.0 1.6 9.7e-08 31.0 1.6 3.5 1 1 2 3 3 3 1 MFS/sugar transport protein Pox_A14 PF05767.12 GAK67637.1 - 0.03 14.5 0.4 0.03 14.5 0.4 3.1 5 0 0 5 5 5 0 Poxvirus virion envelope protein A14 DUF5368 PF17336.2 GAK67637.1 - 0.68 10.1 6.5 0.14 12.3 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5368) ABC_membrane PF00664.23 GAK67638.1 - 2.1e-63 214.6 22.6 2.3e-35 122.6 8.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK67638.1 - 2.3e-49 167.4 0.1 1.6e-27 96.7 0.1 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAK67638.1 - 7.5e-10 38.6 0.0 3.4e-05 23.4 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAK67638.1 - 1.6e-09 37.9 0.0 0.0023 17.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAK67638.1 - 4.2e-07 30.5 2.3 0.026 14.9 0.2 3.0 2 1 1 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAK67638.1 - 5.8e-06 26.4 0.2 0.14 12.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_7 PF12775.7 GAK67638.1 - 6.6e-06 25.8 1.8 0.033 13.7 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 GAK67638.1 - 9.1e-06 25.3 0.7 0.095 12.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 GAK67638.1 - 2e-05 24.4 1.0 0.011 15.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 GAK67638.1 - 8.7e-05 23.0 0.8 0.12 12.8 0.1 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAK67638.1 - 9.9e-05 22.1 2.5 1.5 8.6 0.1 3.7 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 GAK67638.1 - 0.00011 22.4 1.2 0.04 14.2 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAK67638.1 - 0.00017 21.2 5.4 0.45 10.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain T2SSE PF00437.20 GAK67638.1 - 0.00042 19.5 1.6 0.21 10.6 0.0 2.8 3 0 0 3 3 2 2 Type II/IV secretion system protein MeaB PF03308.16 GAK67638.1 - 0.00043 19.3 2.2 0.038 13.0 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 GAK67638.1 - 0.0011 18.2 1.5 0.69 9.2 0.3 2.7 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.23 GAK67638.1 - 0.004 17.2 3.4 0.25 11.4 0.2 2.9 3 0 0 3 3 3 1 Dynamin family AAA_33 PF13671.6 GAK67638.1 - 0.0052 17.0 3.3 0.54 10.4 1.8 3.2 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 GAK67638.1 - 0.0054 16.5 5.1 2.3 7.9 0.6 3.3 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAK67638.1 - 0.0059 17.0 0.7 1.4 9.3 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Roc PF08477.13 GAK67638.1 - 0.01 16.1 0.7 8.5 6.6 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 GAK67638.1 - 0.023 14.7 3.8 0.75 9.8 0.3 2.7 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 GAK67638.1 - 0.026 13.7 1.3 2.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CbiA PF01656.23 GAK67638.1 - 0.035 14.2 0.0 3.8 7.6 0.0 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 GAK67638.1 - 0.041 13.8 1.1 4 7.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 GAK67638.1 - 0.051 12.9 0.8 1.4 8.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.7 GAK67638.1 - 0.13 11.2 0.1 3.3 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.14 GAK67638.1 - 0.23 11.4 2.2 2.5 8.0 0.2 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 GAK67638.1 - 0.23 11.2 1.2 19 5.0 0.1 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 GAK67638.1 - 0.32 11.1 10.9 0.19 11.8 0.4 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 GAK67638.1 - 0.51 10.6 3.7 0.72 10.1 0.0 3.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.9 GAK67638.1 - 0.69 8.8 3.2 14 4.5 0.3 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 GAK67638.1 - 1.3 8.7 4.5 15 5.2 0.4 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 GAK67638.1 - 1.3 9.5 4.2 4.4 7.8 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 GAK67638.1 - 2.4 8.4 6.7 4 7.6 0.5 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAK67638.1 - 3.8 7.4 6.4 1.5 8.7 0.2 2.9 3 0 0 3 3 3 0 NTPase cobW PF02492.19 GAK67638.1 - 4.1 7.0 7.3 16 5.0 0.3 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_8 PF13523.6 GAK67639.1 - 7.8e-28 97.0 0.9 1.3e-27 96.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 GAK67640.1 - 6.6e-51 173.0 0.0 7.7e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK67640.1 - 3e-26 92.7 0.0 7.5e-26 91.4 0.0 1.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 GAK67641.1 - 8.1e-200 663.8 0.1 4.8e-68 229.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAK67641.1 - 5.6e-135 450.5 0.0 7.9e-41 140.2 0.0 5.7 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.25 GAK67641.1 - 1.7e-40 137.2 5.1 5.2e-09 36.3 0.1 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAK67641.1 - 5.5e-10 40.1 0.3 0.0012 19.8 0.0 4.3 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 GAK67641.1 - 8.3e-08 32.3 5.7 0.23 11.2 0.0 6.0 5 0 0 5 5 5 4 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF2306 PF10067.9 GAK67642.1 - 0.00016 21.9 8.9 0.076 13.2 1.3 2.9 2 1 0 3 3 3 2 Predicted membrane protein (DUF2306) LigB PF02900.18 GAK67645.1 - 6.2e-18 64.8 0.0 7.1e-08 31.9 0.0 2.0 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase ABC1 PF03109.16 GAK67646.1 - 2.5e-31 108.3 0.1 4.7e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 GAK67646.1 - 0.0036 16.9 0.1 0.011 15.4 0.1 1.8 1 1 0 1 1 1 1 RIO1 family UPF0767 PF15990.5 GAK67646.1 - 0.16 12.1 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 UPF0767 family MFS_1 PF07690.16 GAK67647.1 - 4.3e-43 147.6 24.4 4.3e-43 147.6 24.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK67647.1 - 2.1e-16 59.9 0.4 2.1e-16 59.9 0.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter FAD_binding_2 PF00890.24 GAK67648.1 - 1.3e-88 297.9 0.1 1.3e-88 297.9 0.1 1.4 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 GAK67648.1 - 1.3e-20 73.3 0.3 3.8e-20 71.8 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 GAK67648.1 - 3.2e-15 56.6 0.2 6.8e-15 55.5 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAK67648.1 - 1.2e-10 41.4 0.2 1e-09 38.5 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAK67648.1 - 8.3e-10 38.4 0.1 1.3e-07 31.2 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAK67648.1 - 1.3e-09 37.9 0.4 3.4e-09 36.5 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAK67648.1 - 8.3e-07 28.4 0.9 0.0056 15.8 0.5 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 GAK67648.1 - 8.4e-07 28.0 2.4 0.00016 20.5 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAK67648.1 - 1.3e-06 27.9 0.1 0.0075 15.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAK67648.1 - 8.2e-06 25.3 1.7 2.6e-05 23.6 1.7 1.8 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAK67648.1 - 1.6e-05 24.3 0.2 0.0042 16.4 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 GAK67648.1 - 0.00012 22.6 0.8 0.0048 17.4 0.1 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAK67648.1 - 0.00019 20.8 0.3 0.00044 19.6 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GAK67648.1 - 0.00024 20.5 0.2 0.0016 17.8 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 GAK67648.1 - 0.031 14.7 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 GAK67648.1 - 0.032 14.2 0.1 0.48 10.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAK67648.1 - 0.073 12.1 0.2 0.17 10.9 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.18 GAK67648.1 - 0.19 10.2 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Nfu_N PF08712.11 GAK67649.1 - 3.3e-31 107.2 0.0 6.9e-31 106.1 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 GAK67649.1 - 1e-26 92.8 0.1 2.1e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain ECH_1 PF00378.20 GAK67650.1 - 6.5e-86 287.7 1.3 8.1e-86 287.4 1.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK67650.1 - 1.3e-34 120.2 1.9 3.1e-32 112.4 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAK67650.1 - 0.00033 20.7 0.1 0.2 11.6 0.0 2.7 2 1 1 3 3 3 2 Peptidase family S49 GCP_C_terminal PF04130.13 GAK67652.1 - 7.4e-43 147.2 0.8 1.2e-42 146.5 0.8 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAK67652.1 - 2e-15 57.2 0.0 5.2e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF1192 PF06698.11 GAK67652.1 - 1.8 8.7 8.4 0.43 10.7 0.5 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DNA_pol_D_N PF18018.1 GAK67653.1 - 5.5e-39 133.3 0.0 8e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 GAK67653.1 - 6.8e-37 126.9 0.0 1.3e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF3760 PF12586.8 GAK67654.1 - 0.16 12.2 0.4 0.34 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) DUF572 PF04502.13 GAK67655.1 - 3e-77 260.5 4.4 4.8e-77 259.8 4.4 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF4813 PF16072.5 GAK67655.1 - 0.28 10.8 8.1 0.43 10.2 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) zf-ACC PF17848.1 GAK67655.1 - 1.1 9.4 3.9 23 5.2 0.5 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Ribosomal_60s PF00428.19 GAK67655.1 - 6.4 7.4 21.3 1.8 9.2 1.0 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein MARVEL PF01284.23 GAK67656.1 - 0.0045 17.0 11.3 0.0082 16.2 9.7 2.1 1 1 1 2 2 2 1 Membrane-associating domain DUF2583 PF10762.9 GAK67656.1 - 1.6 9.2 3.9 0.34 11.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) CHASE8 PF17152.4 GAK67657.1 - 0.012 15.8 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain DUF2722 PF10846.8 GAK67657.1 - 0.015 14.3 5.1 0.013 14.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RAB3GAP2_N PF14655.6 GAK67657.1 - 0.036 13.3 5.3 0.044 13.0 5.3 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 GAK67657.1 - 0.052 13.2 11.2 0.064 12.9 11.2 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 GAK67657.1 - 0.057 12.3 6.9 0.049 12.5 6.9 1.1 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 GAK67657.1 - 0.088 12.8 7.6 0.082 12.9 7.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 GAK67657.1 - 0.1 11.7 3.0 0.1 11.7 3.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Med3 PF11593.8 GAK67657.1 - 0.3 10.2 9.3 0.35 10.0 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CRAL_TRIO PF00650.20 GAK67658.1 - 4.9e-41 140.1 0.0 7.7e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Hydrolase_6 PF13344.6 GAK67658.1 - 2e-28 98.4 0.0 4e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAK67658.1 - 2.1e-18 66.2 0.0 6.5e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAK67658.1 - 3.2e-11 43.9 0.0 3e-10 40.8 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CRAL_TRIO_2 PF13716.6 GAK67658.1 - 3e-10 40.4 0.0 5.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HAD_2 PF13419.6 GAK67658.1 - 9.2e-07 29.1 0.1 0.00079 19.6 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase CRAL_TRIO_N PF03765.15 GAK67658.1 - 3.7e-05 23.8 0.2 9.7e-05 22.5 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PGP_phosphatase PF09419.10 GAK67658.1 - 0.065 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DFF40 PF09230.10 GAK67659.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa CMD PF02627.20 GAK67660.1 - 1e-09 38.3 0.5 1.1e-08 34.9 0.3 2.5 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family Mito_carr PF00153.27 GAK67661.1 - 2.6e-53 177.9 4.4 8.8e-20 70.4 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein PGM_PMM_I PF02878.16 GAK67663.1 - 9.5e-20 70.7 0.1 3.7e-10 39.6 0.0 2.9 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 GAK67663.1 - 4.9e-09 36.2 0.1 1.3e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 GAK67663.1 - 0.013 15.7 0.1 0.042 14.0 0.1 1.9 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAK67663.1 - 0.041 14.5 0.8 2 9.1 0.3 3.4 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ORMDL PF04061.14 GAK67664.1 - 9.4e-56 187.4 1.9 1.1e-55 187.1 1.9 1.1 1 0 0 1 1 1 1 ORMDL family RIBIOP_C PF04950.12 GAK67665.1 - 1.8e-111 372.2 0.0 4.4e-111 371.0 0.0 1.6 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAK67665.1 - 3.5e-21 75.1 0.0 8.4e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain eIF_4EBP PF05456.11 GAK67666.1 - 3.6e-12 46.2 0.8 4e-12 46.1 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Mito_carr PF00153.27 GAK67667.1 - 7.3e-63 208.5 0.2 5.7e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PAE PF03283.13 GAK67667.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Rad52_Rad22 PF04098.15 GAK67668.1 - 2.2e-55 186.8 0.1 7e-55 185.2 0.0 1.8 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein TFIIA PF03153.13 GAK67668.1 - 3.8 7.4 9.1 6.4 6.7 9.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 GAK67669.1 - 3.2e-69 233.2 0.0 5.4e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67669.1 - 7e-38 130.4 0.0 1.8e-37 129.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAK67669.1 - 8.8e-10 38.2 0.0 1.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 GAK67669.1 - 5e-09 35.9 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAK67669.1 - 0.0086 15.1 0.3 0.021 13.8 0.3 1.6 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 GAK67669.1 - 0.028 14.0 0.2 0.066 12.8 0.2 1.5 1 0 0 1 1 1 0 RIO1 family DUF1687 PF07955.11 GAK67670.1 - 4.8e-14 52.9 0.0 9.1e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) F-box PF00646.33 GAK67671.1 - 2e-08 33.9 0.4 4.8e-08 32.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAK67671.1 - 6e-05 22.8 5.3 0.00017 21.4 5.3 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 GAK67671.1 - 0.018 15.9 0.1 2.4 9.2 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat DDOST_48kD PF03345.14 GAK67672.1 - 3.3e-116 388.6 0.0 4.4e-73 246.5 0.1 2.0 1 1 1 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta Gly_radical PF01228.21 GAK67672.1 - 0.0072 16.8 0.0 0.03 14.9 0.0 2.0 2 0 0 2 2 2 1 Glycine radical Nkap_C PF06047.11 GAK67673.1 - 6.1e-48 161.2 2.4 1.6e-47 159.8 2.4 1.8 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Diphthami_syn_2 PF01902.17 GAK67674.1 - 4e-38 131.1 0.0 1.9e-26 92.9 0.0 2.3 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GAK67674.1 - 6.9e-14 51.9 0.0 4.5e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.16 GAK67674.1 - 0.029 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Adeno_E3 PF06040.11 GAK67674.1 - 0.33 11.1 0.8 20 5.4 0.0 2.8 3 0 0 3 3 3 0 Adenovirus E3 protein SUV3_C PF12513.8 GAK67675.1 - 1.1e-13 50.8 0.1 4.1e-13 49.0 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 GAK67675.1 - 5.5e-12 46.0 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 GAK67675.1 - 0.00023 20.9 0.1 0.00056 19.7 0.1 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 LrgB PF04172.16 GAK67676.1 - 1.2e-33 116.5 11.3 1.2e-33 116.5 11.3 2.7 3 0 0 3 3 3 1 LrgB-like family LrgA PF03788.14 GAK67676.1 - 6.1e-05 22.9 2.4 6.1e-05 22.9 2.4 3.2 4 1 1 5 5 5 1 LrgA family Myc_N PF01056.18 GAK67676.1 - 0.0031 17.5 3.4 0.0049 16.8 3.4 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF3464 PF11947.8 GAK67676.1 - 0.0042 16.9 0.5 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 BSP_II PF05432.11 GAK67676.1 - 0.13 11.9 6.1 0.07 12.8 4.1 1.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Endomucin PF07010.12 GAK67676.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Endomucin FAM176 PF14851.6 GAK67676.1 - 0.22 11.2 2.6 0.42 10.3 2.6 1.4 1 0 0 1 1 1 0 FAM176 family DUF4079 PF13301.6 GAK67676.1 - 6.3 6.9 7.9 11 6.2 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) PAS PF00989.25 GAK67677.1 - 0.21 11.6 0.1 0.59 10.1 0.0 1.7 2 0 0 2 2 2 0 PAS fold LCM PF04072.14 GAK67679.1 - 2.8e-17 63.3 0.0 4.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Scs3p PF10261.9 GAK67680.1 - 3.4e-64 216.7 0.8 6.9e-64 215.7 0.8 1.5 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Ribosomal_S17 PF00366.20 GAK67682.1 - 3.5e-22 78.3 0.1 3.5e-22 78.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 B-block_TFIIIC PF04182.12 GAK67683.1 - 4.7e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_micro PF17007.5 GAK67683.1 - 0.0058 15.5 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 HTH-like MarR_2 PF12802.7 GAK67683.1 - 0.0066 16.3 0.1 0.69 9.8 0.0 3.7 3 1 1 4 4 4 1 MarR family F-box-like PF12937.7 GAK67684.1 - 1.9e-09 37.3 0.5 4.4e-09 36.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK67684.1 - 3.1e-06 26.9 0.1 1.1e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 GAK67684.1 - 0.0011 19.7 0.0 1.5 9.8 0.0 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat SUZ PF12752.7 GAK67684.1 - 1.8 9.4 5.6 12 6.7 5.6 2.6 1 0 0 1 1 1 0 SUZ domain Ribosomal_L28e PF01778.17 GAK67685.1 - 1.1e-26 93.8 1.9 1.9e-26 93.1 1.9 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF4235 PF14019.6 GAK67685.1 - 0.027 14.5 1.7 0.049 13.7 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) PA-IIL PF07472.11 GAK67685.1 - 0.13 12.6 1.0 0.25 11.7 1.0 1.5 1 1 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) Hydrophobin PF01185.18 GAK67686.1 - 4.2e-15 56.1 10.9 5.2e-15 55.8 10.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin ApoO PF09769.9 GAK67687.1 - 1.7e-28 99.2 5.9 3e-28 98.4 0.3 2.9 1 1 3 4 4 4 1 Apolipoprotein O ATP-synt_B PF00430.18 GAK67687.1 - 0.012 15.7 3.3 0.012 15.7 3.3 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) YabA PF06156.13 GAK67688.1 - 0.051 14.2 4.7 0.12 13.1 4.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 GAK67688.1 - 0.68 10.5 13.1 1.2 9.7 13.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Mod_r PF07200.13 GAK67688.1 - 0.91 9.6 10.6 1.8 8.7 10.3 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.12 GAK67688.1 - 1.6 9.4 12.1 1.2 9.8 9.9 2.0 2 0 0 2 2 2 0 SlyX UPF0242 PF06785.11 GAK67688.1 - 1.6 8.8 9.8 2.2 8.3 9.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 GAK67688.1 - 1.9 8.6 11.5 3.7 7.7 11.5 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase HALZ PF02183.18 GAK67688.1 - 2.7 8.3 6.0 1.3 9.4 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper CENP-H PF05837.12 GAK67688.1 - 3.4 8.1 10.9 6.7 7.2 10.9 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PAP_assoc PF03828.19 GAK67690.1 - 2.2e-13 50.2 0.1 4.6e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAK67690.1 - 1.8e-05 25.0 0.0 3.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAK67690.1 - 0.015 15.4 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Pkinase PF00069.25 GAK67691.1 - 3.4e-51 174.2 0.0 4.6e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67691.1 - 2.8e-35 121.8 0.0 4.3e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK67691.1 - 2e-07 30.2 0.2 6.1e-07 28.6 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase PBD PF00786.28 GAK67691.1 - 2.7e-06 27.6 0.0 7.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 GAK67691.1 - 0.013 14.8 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like UBA_4 PF14555.6 GAK67694.1 - 2.7e-10 39.9 0.0 7.9e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 GAK67694.1 - 2.5e-05 23.9 11.8 0.019 14.8 3.3 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif TAP_C PF03943.13 GAK67694.1 - 0.00071 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain UCH PF00443.29 GAK67694.1 - 0.011 15.2 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase VIR_N PF15912.5 GAK67694.1 - 3.3 7.2 7.7 7.7 6.0 7.7 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal S4 PF01479.25 GAK67695.1 - 6.1e-12 45.1 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain Rtf2 PF04641.12 GAK67695.1 - 1.1 8.5 6.8 2 7.7 6.8 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger PPP4R2 PF09184.11 GAK67695.1 - 2.8 7.5 5.1 4.1 6.9 5.1 1.2 1 0 0 1 1 1 0 PPP4R2 S-AdoMet_synt_C PF02773.16 GAK67696.1 - 4.9e-66 220.9 0.4 1.2e-65 219.7 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GAK67696.1 - 1.4e-46 157.6 0.0 2.9e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GAK67696.1 - 1.8e-45 153.7 0.3 3.9e-45 152.6 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 GAK67696.1 - 0.025 13.4 0.1 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) HemN_C PF06969.16 GAK67696.1 - 0.21 11.7 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 HemN C-terminal domain MFS_1 PF07690.16 GAK67697.1 - 7.8e-38 130.3 52.9 1.4e-24 86.7 25.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.22 GAK67698.1 - 2.7e-45 154.7 0.0 7.2e-45 153.4 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 GAK67699.1 - 1.4e-13 50.5 42.7 1.7e-13 50.2 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.21 GAK67700.1 - 2e-118 396.0 47.4 2.4e-118 395.8 47.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK67700.1 - 1.4e-32 113.1 50.6 1.9e-32 112.6 50.6 1.2 1 0 0 1 1 1 1 Amino acid permease ALS_ss_C PF10369.9 GAK67701.1 - 8.7e-20 70.7 0.0 1.1e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.25 GAK67701.1 - 1.3e-12 47.3 0.0 2.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 GAK67701.1 - 1.2e-06 28.2 0.0 2.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 ACT domain DUF2187 PF09953.9 GAK67701.1 - 0.017 15.1 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) Pkinase PF00069.25 GAK67703.1 - 1.2e-55 188.7 0.0 9e-55 185.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67703.1 - 3.4e-27 95.4 0.0 4.8e-26 91.6 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.6 GAK67703.1 - 2.1e-06 27.8 0.0 2.5e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 PH domain Kdo PF06293.14 GAK67703.1 - 9.7e-06 25.1 0.1 1.6e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAK67703.1 - 0.00048 19.5 0.0 0.00092 18.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAK67703.1 - 0.0057 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAK67703.1 - 0.069 12.1 0.0 0.069 12.1 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Sugar_tr PF00083.24 GAK67704.1 - 7.2e-127 424.0 22.8 8.4e-127 423.7 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK67704.1 - 3.5e-24 85.4 38.8 4.6e-19 68.6 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 GAK67704.1 - 2 8.7 14.3 0.24 11.7 4.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF3792 PF12670.7 GAK67704.1 - 5.7 7.1 31.9 0.49 10.6 5.4 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3792) Med1 PF10744.9 GAK67705.1 - 1.4e-08 34.2 0.0 0.00025 20.2 0.0 2.2 1 1 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Methyltransf_11 PF08241.12 GAK67705.1 - 0.00013 22.5 0.0 0.00061 20.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK67705.1 - 0.00018 22.1 0.1 0.0018 19.0 0.1 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK67705.1 - 0.0039 17.1 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK67705.1 - 0.15 11.8 0.0 0.65 9.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 GAK67706.1 - 2.8e-08 34.3 4.6 0.082 13.8 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat NUP50 PF08911.11 GAK67707.1 - 1.9e-06 28.4 0.3 1.9e-06 28.4 0.3 9.9 7 4 0 7 7 7 1 NUP50 (Nucleoporin 50 kDa) SDA1 PF05285.12 GAK67707.1 - 0.0005 19.6 22.9 0.001 18.6 22.9 1.5 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAK67707.1 - 0.00091 17.6 26.6 0.00091 17.6 26.6 1.7 2 0 0 2 2 2 1 Nop14-like family CDC45 PF02724.14 GAK67707.1 - 0.83 7.9 21.6 1.3 7.3 21.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GAK67707.1 - 2.6 6.4 27.6 4.2 5.7 27.6 1.2 1 0 0 1 1 1 0 Mpp10 protein COPI_C PF06957.11 GAK67707.1 - 4 6.1 17.3 6.4 5.4 17.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ribosomal_L1 PF00687.21 GAK67708.1 - 8.7e-48 162.8 3.5 1e-47 162.6 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DNA_pol_lambd_f PF10391.9 GAK67708.1 - 0.049 13.5 0.1 5.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Mod_r PF07200.13 GAK67708.1 - 0.053 13.6 1.8 0.16 12.1 0.3 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TetR PF13972.6 GAK67708.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor Band_7 PF01145.25 GAK67709.1 - 8.1e-22 78.1 0.3 8.1e-22 78.1 0.3 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Actin PF00022.19 GAK67710.1 - 8.8e-35 120.1 0.0 4.6e-34 117.7 0.0 2.1 1 1 0 1 1 1 1 Actin Dna2 PF08696.11 GAK67711.1 - 6.4e-46 156.7 0.0 4.9e-45 153.9 0.0 2.2 1 1 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 GAK67711.1 - 1.9e-45 155.0 0.0 3.8e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAK67711.1 - 2.8e-30 106.0 0.0 6.1e-15 55.7 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 GAK67711.1 - 2.6e-14 53.4 0.0 1.1e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAK67711.1 - 2.9e-11 43.9 0.0 1e-10 42.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 GAK67711.1 - 8.1e-06 25.8 0.1 7.8e-05 22.6 0.0 2.5 2 1 0 2 2 1 1 Helicase Viral_helicase1 PF01443.18 GAK67711.1 - 0.0001 22.2 0.1 0.22 11.3 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 GAK67711.1 - 0.00027 20.6 0.2 0.00052 19.7 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 GAK67711.1 - 0.0005 19.7 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_17 PF13207.6 GAK67711.1 - 0.0023 18.4 0.0 0.014 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 GAK67711.1 - 0.0024 17.3 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain CbiA PF01656.23 GAK67711.1 - 0.0031 17.6 0.1 0.0072 16.4 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Cas_Cas4 PF01930.17 GAK67711.1 - 0.008 16.3 0.4 0.029 14.5 0.0 2.1 2 0 0 2 2 1 1 Domain of unknown function DUF83 AAA_16 PF13191.6 GAK67711.1 - 0.014 15.8 1.8 0.045 14.1 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain MeaB PF03308.16 GAK67711.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 GAK67711.1 - 0.022 14.9 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 GAK67711.1 - 0.029 13.4 0.1 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 GAK67711.1 - 0.032 14.2 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Orbi_VP5 PF00901.17 GAK67711.1 - 0.047 12.1 0.0 0.076 11.4 0.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 AAA_22 PF13401.6 GAK67711.1 - 0.063 13.5 0.0 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAK67711.1 - 0.068 13.3 0.0 19 5.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 GAK67711.1 - 0.074 13.2 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAK67711.1 - 0.089 12.4 0.4 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 GAK67711.1 - 0.09 12.7 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 GAK67711.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAK67711.1 - 0.22 11.4 0.2 0.47 10.3 0.2 1.5 1 0 0 1 1 1 0 NTPase Apt1 PF10351.9 GAK67712.1 - 0.4 9.5 21.2 0.62 8.9 21.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 GAK67712.1 - 2.8 7.8 26.6 4.4 7.1 26.6 1.2 1 0 0 1 1 1 0 SPX domain E1-E2_ATPase PF00122.20 GAK67713.1 - 9.1e-39 132.8 8.8 2.8e-38 131.2 6.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAK67713.1 - 7.6e-37 126.8 14.9 2.3e-35 121.9 3.3 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAK67713.1 - 2.9e-21 76.7 0.6 9e-10 39.2 0.7 3.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAK67713.1 - 3.1e-13 49.2 0.0 6.4e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAK67713.1 - 2.1e-09 37.3 0.0 5.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAK67713.1 - 0.00039 20.2 0.2 0.00074 19.3 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4149 PF13664.6 GAK67713.1 - 0.0014 18.9 3.0 0.093 13.1 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2157 PF09925.9 GAK67713.1 - 0.0053 16.5 0.0 0.0053 16.5 0.0 3.4 3 1 0 3 3 3 1 Predicted membrane protein (DUF2157) HAD PF12710.7 GAK67713.1 - 0.035 14.5 0.0 0.37 11.2 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4411 PF14367.6 GAK67713.1 - 0.14 12.0 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DUF2207 PF09972.9 GAK67713.1 - 0.55 8.9 5.6 1.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Ins_P5_2-kin PF06090.12 GAK67714.1 - 1.7e-67 228.2 0.0 2e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Cmc1 PF08583.10 GAK67715.1 - 6.6e-16 58.1 4.5 8.1e-16 57.8 4.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 GAK67715.1 - 1.3e-05 25.1 0.6 2.4e-05 24.3 0.6 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 GAK67715.1 - 0.0045 17.2 2.1 1.3 9.3 0.3 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 GAK67715.1 - 0.035 14.2 4.2 0.11 12.7 1.0 2.4 2 0 0 2 2 2 0 CHCH domain Ribosomal_S3Ae PF01015.18 GAK67716.1 - 9.2e-91 302.9 2.8 1.1e-90 302.6 2.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 GAK67716.1 - 0.022 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region ISAV_HA PF06215.11 GAK67716.1 - 0.063 12.4 0.1 0.091 11.9 0.1 1.1 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Ribosomal_S7e PF01251.18 GAK67718.1 - 7e-85 283.4 0.3 8e-85 283.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RasGAP PF00616.19 GAK67719.1 - 1.2e-25 90.5 0.0 1.8e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 GAK67719.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 C2 domain Glyoxalase_3 PF13468.6 GAK67720.1 - 4.1e-26 92.2 0.0 6e-25 88.4 0.0 2.3 1 1 0 1 1 1 1 Glyoxalase-like domain GYF PF02213.16 GAK67721.1 - 4.2e-06 26.3 0.0 9.7e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 GYF domain Pkinase PF00069.25 GAK67722.1 - 1.3e-66 224.7 0.0 4.7e-36 124.5 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67722.1 - 2.9e-34 118.5 0.0 1.8e-16 60.2 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 GAK67722.1 - 2.9e-18 66.2 0.1 8.3e-18 64.7 0.1 1.8 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 GAK67722.1 - 2.7e-17 63.2 7.3 4.6e-15 55.9 0.0 3.9 5 0 0 5 5 5 1 Anticodon binding domain of tRNAs RWD PF05773.22 GAK67722.1 - 2e-14 53.8 0.0 4.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 GAK67722.1 - 0.00011 21.7 0.0 0.029 13.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 GAK67722.1 - 0.0018 17.7 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAK67722.1 - 0.0039 17.1 5.0 0.0095 15.9 0.0 3.8 4 0 0 4 4 4 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAK67722.1 - 0.02 14.6 0.0 5.2 6.6 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 CENP-B_dimeris PF09026.10 GAK67722.1 - 0.031 14.7 8.9 0.023 15.1 1.5 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Pkinase_fungal PF17667.1 GAK67722.1 - 0.19 10.5 1.4 0.28 9.9 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase GCD14_N PF14801.6 GAK67723.1 - 0.0025 17.6 0.1 0.0079 16.0 0.0 1.8 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term DPBB_1 PF03330.18 GAK67723.1 - 0.0072 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Questin_oxidase PF14027.6 GAK67724.1 - 1.1e-71 242.2 3.4 1.7e-71 241.6 3.4 1.3 1 0 0 1 1 1 1 Questin oxidase-like DUF3140 PF11338.8 GAK67725.1 - 6.2e-33 113.1 3.6 6.2e-33 113.1 3.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) Med22 PF06179.12 GAK67725.1 - 5.2e-12 45.9 2.0 2.3e-11 43.9 2.0 2.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Casein PF00363.18 GAK67725.1 - 0.35 11.3 2.6 0.21 12.0 0.4 1.7 2 0 0 2 2 2 0 Casein DUF3237 PF11578.8 GAK67726.1 - 2.2e-37 128.2 0.2 2.5e-37 128.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Zn_clus PF00172.18 GAK67727.1 - 2.6e-05 24.2 9.9 5.4e-05 23.2 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.15 GAK67728.1 - 1.5e-51 175.4 0.7 1.2e-25 90.7 0.0 3.7 2 2 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_25 PF13649.6 GAK67728.1 - 0.00029 21.5 0.6 0.071 13.8 0.1 3.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK67728.1 - 0.0021 18.7 0.8 0.024 15.3 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK67728.1 - 0.0042 16.9 0.0 0.27 11.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain CD99L2 PF12301.8 GAK67728.1 - 0.0062 16.8 6.2 0.0062 16.8 6.2 2.2 1 1 0 2 2 2 1 CD99 antigen like protein 2 Methyltransf_32 PF13679.6 GAK67728.1 - 0.16 11.9 1.8 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain NARP1 PF12569.8 GAK67728.1 - 4.2 6.1 8.8 3.9 6.3 7.5 1.6 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 CDT1_C PF16679.5 GAK67729.1 - 1.5e-16 60.6 0.2 4.1e-16 59.2 0.2 1.7 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Trp_repressor PF01371.19 GAK67729.1 - 0.18 11.9 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Trp repressor protein DUF924 PF06041.11 GAK67730.1 - 6.3e-47 160.0 0.4 8e-47 159.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Forkhead PF00250.18 GAK67731.1 - 3.7e-18 65.5 0.0 7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 GAK67731.1 - 0.16 12.4 0.0 0.66 10.4 0.0 1.9 1 1 0 1 1 1 0 FHA domain TFIIA PF03153.13 GAK67733.1 - 0.58 10.1 33.5 0.51 10.3 23.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ytp1 PF10355.9 GAK67734.1 - 9.8e-102 339.9 2.2 9.8e-102 339.9 2.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAK67734.1 - 6.2e-18 64.5 0.4 6.2e-18 64.5 0.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Abhydrolase_3 PF07859.13 GAK67735.1 - 2.5e-22 79.8 0.0 7.2e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAK67735.1 - 3.2e-13 49.3 0.0 1.3e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Steryl acetyl hydrolase COesterase PF00135.28 GAK67735.1 - 0.084 11.7 0.0 0.76 8.6 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family SSB PF00436.25 GAK67736.1 - 8.8e-14 51.4 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Aminotran_1_2 PF00155.21 GAK67737.1 - 5e-74 249.7 0.0 8.3e-74 248.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAK67737.1 - 1.1e-06 27.9 0.1 2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAK67737.1 - 3e-05 22.7 0.0 0.00015 20.4 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Preseq_ALAS PF09029.10 GAK67737.1 - 0.0008 19.9 6.4 0.003 18.0 3.4 2.7 1 1 1 2 2 2 1 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.17 GAK67737.1 - 0.0051 16.2 0.2 0.0094 15.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAK67737.1 - 0.013 14.8 0.4 0.029 13.6 0.4 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Ribosomal_L12 PF00542.19 GAK67738.1 - 1.4e-19 70.2 10.7 1.5e-19 70.1 4.4 2.3 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GAK67738.1 - 1e-15 57.1 10.1 5.2e-15 54.9 6.6 2.5 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 GAK67738.1 - 0.038 14.6 8.3 0.038 14.6 8.3 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein EutN_CcmL PF03319.13 GAK67738.1 - 0.11 13.2 0.2 7.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutN/carboxysome DAO PF01266.24 GAK67739.1 - 7.9e-52 177.0 0.9 1.6e-51 176.0 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK67739.1 - 0.00038 19.8 0.0 0.0009 18.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAK67739.1 - 0.0012 19.4 0.1 0.022 15.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK67739.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAK67739.1 - 0.0038 16.4 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAK67739.1 - 0.0092 15.2 0.0 0.032 13.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GAK67739.1 - 0.023 14.1 0.2 0.19 11.1 0.2 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Mqo PF06039.15 GAK67739.1 - 0.099 11.2 0.0 0.18 10.3 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 GAK67739.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Lactate_perm PF02652.14 GAK67739.1 - 0.29 9.8 0.0 0.44 9.2 0.0 1.1 1 0 0 1 1 1 0 L-lactate permease Snf7 PF03357.21 GAK67740.1 - 1.6e-43 148.3 13.2 1.6e-43 148.3 13.2 2.0 2 0 0 2 2 2 1 Snf7 FAM199X PF15814.5 GAK67740.1 - 0.015 14.4 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X Xylo_C PF12529.8 GAK67740.1 - 0.025 14.2 0.4 0.034 13.8 0.4 1.2 1 0 0 1 1 1 0 Xylosyltransferase C terminal Ribosomal_60s PF00428.19 GAK67740.1 - 0.047 14.3 7.7 0.47 11.1 1.9 2.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein SBDS_C PF09377.10 GAK67740.1 - 0.062 13.3 3.7 0.14 12.2 3.6 1.9 1 1 0 1 1 1 0 SBDS protein C-terminal domain Vps54_N PF10475.9 GAK67740.1 - 0.43 9.8 6.3 1.5 8.0 5.8 1.9 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Atg14 PF10186.9 GAK67740.1 - 1.3 8.0 9.5 2 7.4 9.5 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RasGEF PF00617.19 GAK67741.1 - 5.9e-44 150.4 0.0 9.1e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAK67741.1 - 1.8e-15 57.1 0.2 5.4e-15 55.5 0.2 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif MCM PF00493.23 GAK67742.1 - 1e-103 345.3 0.0 1.5e-103 344.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAK67742.1 - 1.9e-35 121.5 0.1 3.6e-35 120.5 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAK67742.1 - 6e-29 100.3 0.5 1.5e-28 99.0 0.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAK67742.1 - 4.4e-13 49.7 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAK67742.1 - 1.7e-06 27.6 0.0 0.00068 19.1 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAK67742.1 - 0.00017 21.6 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAK67742.1 - 0.00098 19.0 0.1 0.0062 16.4 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 GAK67742.1 - 0.075 13.7 0.1 0.24 12.1 0.1 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 GAK67742.1 - 0.082 12.6 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TIG PF01833.24 GAK67743.1 - 4.5e-11 42.7 3.6 4.5e-11 42.7 3.6 2.8 3 0 0 3 3 3 1 IPT/TIG domain Ank_5 PF13857.6 GAK67743.1 - 4.3e-09 36.5 1.0 1.1e-08 35.1 0.5 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAK67743.1 - 7.2e-09 36.1 0.0 1.6e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK67743.1 - 6e-08 33.1 0.8 5.5e-07 30.0 0.3 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAK67743.1 - 6.6e-08 32.2 0.4 0.011 16.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAK67743.1 - 1.1e-06 28.8 0.7 0.026 15.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Glyco_transf_17 PF04724.13 GAK67744.1 - 2.7e-134 447.7 0.0 3.2e-134 447.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 SnoaL_4 PF13577.6 GAK67745.1 - 6.7e-10 39.2 0.2 1.5e-09 38.1 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 GAK67745.1 - 0.071 13.8 0.2 0.13 12.9 0.2 1.4 1 0 0 1 1 1 0 SnoaL-like domain PALP PF00291.25 GAK67746.1 - 1.2e-34 120.1 0.0 2.1e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 GAK67747.1 - 1.8e-45 155.4 60.7 6.9e-38 130.5 41.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAK67747.1 - 6.6e-21 74.4 19.6 8.7e-21 74.0 19.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAK67747.1 - 5.2e-16 58.5 2.3 5.2e-16 58.5 2.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Retrotran_gag_3 PF14244.6 GAK67749.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ENTH PF01417.20 GAK67749.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 ENTH domain Tfb2 PF03849.14 GAK67750.1 - 8.2e-142 472.4 0.0 1e-141 472.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GAK67750.1 - 7.5e-22 77.5 0.3 2e-21 76.2 0.1 1.8 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GAK67750.1 - 0.0012 19.0 0.0 0.0058 16.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Diphthamide_syn PF01866.17 GAK67751.1 - 2e-81 273.8 0.0 1.1e-48 166.2 0.0 2.1 1 1 1 2 2 2 2 Putative diphthamide synthesis protein WRNPLPNID PF15017.6 GAK67751.1 - 0.26 12.2 3.6 38 5.2 6.0 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box VIT1 PF01988.19 GAK67752.1 - 6.7e-66 222.2 4.5 1.4e-65 221.1 4.5 1.5 1 1 0 1 1 1 1 VIT family RecX PF02631.16 GAK67752.1 - 0.0061 17.0 1.4 0.0095 16.4 1.4 1.3 1 0 0 1 1 1 1 RecX family MRC1 PF09444.10 GAK67753.1 - 6.3e-32 111.1 24.9 6.3e-32 111.1 24.9 7.3 6 1 0 6 6 6 1 MRC1-like domain RAMP4 PF06624.12 GAK67753.1 - 4.3e-06 26.7 0.8 4.1e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 Ribosome associated membrane protein RAMP4 DUF2937 PF11157.8 GAK67753.1 - 5.8 6.6 6.6 10 5.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) KH_6 PF15985.5 GAK67754.1 - 5.6e-11 42.6 0.1 1.6e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 GAK67754.1 - 1.2e-06 28.3 15.4 3e-05 23.8 15.4 2.9 1 1 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Alpha_E1_glycop PF01589.16 GAK67754.1 - 0.091 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein Mito_carr PF00153.27 GAK67755.1 - 7.1e-60 199.0 0.1 2.1e-19 69.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_22 PF03901.17 GAK67756.1 - 3.8e-70 237.2 0.0 4.9e-53 180.9 0.0 3.0 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family WD40 PF00400.32 GAK67757.1 - 9e-09 35.8 9.6 0.00087 20.1 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Vps26 PF03643.15 GAK67759.1 - 3.1e-131 436.4 4.3 3.6e-131 436.2 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 GAK67759.1 - 0.002 18.6 0.2 0.098 13.1 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAK67759.1 - 0.0038 17.3 0.7 0.73 9.9 0.1 3.2 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Trm112p PF03966.16 GAK67760.1 - 4e-19 68.9 0.5 7.3e-19 68.1 0.5 1.4 1 1 0 1 1 1 1 Trm112p-like protein GPI-anchored PF10342.9 GAK67761.1 - 0.00013 22.6 0.2 0.00019 22.1 0.2 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_H PF00075.24 GAK67762.1 - 4.9e-35 120.8 0.0 7.7e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 GAK67762.1 - 1.7e-15 57.0 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF2370 PF10176.9 GAK67762.1 - 0.051 13.2 0.9 0.14 11.8 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) RVT_3 PF13456.6 GAK67762.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase-like F5_F8_type_C PF00754.25 GAK67763.1 - 2.4e-05 24.4 0.0 3.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Laminin_N PF00055.17 GAK67763.1 - 0.00048 19.8 0.0 0.00061 19.5 0.0 1.1 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) DUF1765 PF08578.10 GAK67765.1 - 5.2e-27 94.8 1.5 1.2e-26 93.7 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SasG_E PF17041.5 GAK67765.1 - 0.38 10.8 1.3 16 5.6 0.3 2.6 2 0 0 2 2 2 0 E domain SQS_PSY PF00494.19 GAK67766.1 - 5.2e-81 272.0 5.8 8.8e-81 271.3 5.8 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase FAD_binding_1 PF00667.20 GAK67767.1 - 3.4e-57 193.6 0.0 5.2e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAK67767.1 - 9.9e-34 116.6 0.3 2.3e-33 115.4 0.3 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAK67767.1 - 3.7e-22 79.0 0.0 1.3e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF455 PF04305.14 GAK67767.1 - 0.047 13.2 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Abhydrolase_3 PF07859.13 GAK67768.1 - 2.2e-32 112.7 0.1 3.1e-23 82.7 0.0 2.9 2 0 0 2 2 2 2 alpha/beta hydrolase fold LAT PF15234.6 GAK67768.1 - 0.0071 16.1 6.5 0.02 14.6 6.5 1.7 1 0 0 1 1 1 1 Linker for activation of T-cells Say1_Mug180 PF10340.9 GAK67768.1 - 0.045 12.6 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 GAK67768.1 - 0.055 12.7 0.3 1 8.5 0.2 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DNA_pol_phi PF04931.13 GAK67768.1 - 3.9 5.5 6.3 7.1 4.6 6.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi ArfGap PF01412.18 GAK67769.1 - 2.7e-41 140.3 2.3 5.2e-41 139.4 2.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Med11 PF10280.9 GAK67769.1 - 1.6e-10 41.6 0.0 3.4e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Mediator complex protein Fmp27_WPPW PF10359.9 GAK67769.1 - 0.12 11.2 0.9 0.19 10.5 0.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SPC22 PF04573.12 GAK67770.1 - 1.8e-50 170.8 0.6 2.1e-50 170.5 0.6 1.0 1 0 0 1 1 1 1 Signal peptidase subunit AT_hook PF02178.19 GAK67771.1 - 0.0021 17.7 59.4 1.2 9.3 2.2 6.7 5 0 0 5 5 5 5 AT hook motif PAS_3 PF08447.12 GAK67772.1 - 3.8e-06 27.1 2.0 0.0013 19.0 0.0 2.6 2 1 0 2 2 2 2 PAS fold Zn_clus PF00172.18 GAK67772.1 - 0.00031 20.8 8.7 0.0005 20.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAK67772.1 - 0.0095 15.9 0.6 0.02 14.9 0.0 1.7 2 0 0 2 2 2 1 PAS fold SUIM_assoc PF16619.5 GAK67772.1 - 0.32 11.1 7.2 1.3 9.1 7.2 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 YjbE PF11106.8 GAK67773.1 - 1.8 8.8 7.8 0.24 11.7 2.2 2.0 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE LAG1-DNAbind PF09271.11 GAK67775.1 - 3.1e-46 157.7 2.4 3.9e-45 154.2 0.0 2.7 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 GAK67775.1 - 2.1e-19 70.2 0.0 7.8e-19 68.4 0.0 2.0 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain FSH1 PF03959.13 GAK67776.1 - 3.2e-57 193.6 0.0 3.2e-57 193.6 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Homeodomain PF00046.29 GAK67776.1 - 1.1e-16 60.4 3.2 2.6e-16 59.2 3.2 1.7 1 0 0 1 1 1 1 Homeodomain Cyt-b5 PF00173.28 GAK67776.1 - 1.6e-09 37.7 0.4 3.3e-09 36.8 0.4 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DDDD PF10161.9 GAK67776.1 - 0.2 11.4 0.3 1 9.1 0.0 2.3 3 0 0 3 3 3 0 Putative mitochondrial precursor protein MCM_bind PF09739.9 GAK67776.1 - 3.6 5.9 14.4 7.5 4.9 14.4 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CASP_C PF08172.12 GAK67777.1 - 1.8e-76 256.8 0.8 1.8e-76 256.8 0.8 4.3 3 1 0 3 3 3 1 CASP C terminal Gon7 PF08738.10 GAK67777.1 - 0.0021 18.1 0.5 0.0021 18.1 0.5 5.0 4 2 1 5 5 5 1 Gon7 family ZapB PF06005.12 GAK67777.1 - 0.01 16.3 0.2 0.01 16.3 0.2 8.3 6 3 1 7 7 7 0 Cell division protein ZapB PKcGMP_CC PF16808.5 GAK67777.1 - 0.015 15.1 0.8 0.015 15.1 0.8 5.7 6 1 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 GAK67777.1 - 0.6 10.8 0.1 0.6 10.8 0.1 9.0 6 3 5 11 11 11 0 SlyX DUF3220 PF11516.8 GAK67777.1 - 1.9 8.7 6.5 1.4 9.2 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3120) HTH_1 PF00126.27 GAK67777.1 - 4.1 7.4 14.6 0.066 13.2 2.0 4.0 3 2 1 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family FlaC_arch PF05377.11 GAK67777.1 - 4.4 7.8 18.5 0.85 10.1 0.3 6.0 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) CPSase_sm_chain PF00988.22 GAK67778.1 - 6.5e-44 148.9 0.0 1e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAK67778.1 - 4.8e-39 134.1 0.0 7.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAK67778.1 - 2.1e-06 27.6 0.9 7.4e-05 22.6 0.9 2.2 1 1 0 1 1 1 1 Peptidase C26 Peptidase_M22 PF00814.25 GAK67778.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family DUF1749 PF08538.10 GAK67779.1 - 5.2e-61 206.3 0.0 2.9e-46 157.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 GAK67779.1 - 0.00027 21.6 2.5 0.00049 20.8 2.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAK67779.1 - 0.00068 19.2 0.1 0.72 9.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAK67779.1 - 0.0014 17.6 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 GAK67779.1 - 0.0021 17.9 0.1 0.0044 16.9 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase DUF900 PF05990.12 GAK67779.1 - 0.0047 16.5 0.1 0.0069 15.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.8 GAK67779.1 - 0.058 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 GAK67779.1 - 0.094 12.0 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 GAK67779.1 - 0.24 10.9 0.0 0.57 9.7 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase ZapB PF06005.12 GAK67780.1 - 0.013 15.9 0.3 0.013 15.9 0.3 5.0 4 1 0 5 5 5 0 Cell division protein ZapB YabA PF06156.13 GAK67780.1 - 0.021 15.5 18.9 0.21 12.3 1.0 4.5 3 1 1 4 4 4 0 Initiation control protein YabA DASH_Dam1 PF08653.10 GAK67780.1 - 0.39 10.5 1.1 36 4.3 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF5082 PF16888.5 GAK67780.1 - 0.53 10.6 13.0 0.17 12.2 1.4 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) SKA2 PF16740.5 GAK67780.1 - 0.71 9.7 20.3 0.34 10.7 0.8 3.5 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 HALZ PF02183.18 GAK67780.1 - 0.87 9.9 9.3 0.28 11.4 0.9 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper MCC-bdg_PDZ PF10506.9 GAK67780.1 - 0.92 9.6 5.3 0.84 9.7 1.1 2.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Spectrin PF00435.21 GAK67780.1 - 1.8 9.1 22.0 1.9 9.0 0.9 4.0 4 0 0 4 4 3 0 Spectrin repeat GIT_CC PF16559.5 GAK67780.1 - 2.7 7.9 18.3 0.087 12.7 1.0 4.0 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 GAK67780.1 - 2.8 8.0 9.4 0.76 9.8 1.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Chibby PF14645.6 GAK67780.1 - 5.1 7.5 6.0 2.8 8.4 0.8 3.0 3 0 0 3 3 3 0 Chibby family Shugoshin_N PF07558.11 GAK67780.1 - 5.1 7.0 5.9 0.72 9.8 0.7 2.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region TMF_DNA_bd PF12329.8 GAK67780.1 - 9.8 6.3 25.5 0.055 13.5 1.9 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding ABA_GPCR PF12430.8 GAK67781.1 - 5.1e-46 156.7 6.1 9.6e-46 155.8 6.1 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 GAK67781.1 - 3.2e-16 59.2 0.2 2.7e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DASH_Duo1 PF08651.10 GAK67782.1 - 8e-21 73.6 0.2 1.4e-20 72.8 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 TRP PF06011.12 GAK67785.1 - 1.4e-61 208.6 10.6 2.6e-61 207.7 10.6 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAK67785.1 - 2.7e-29 102.3 0.4 4.1e-29 101.7 0.4 1.3 1 0 0 1 1 1 1 ML-like domain Rax2 PF12768.7 GAK67785.1 - 0.098 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF21 PF01595.20 GAK67786.1 - 1.2e-38 132.5 1.7 2.8e-38 131.4 0.6 1.9 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAK67786.1 - 2.6e-05 24.6 0.9 0.11 12.9 0.0 3.3 3 1 0 3 3 3 2 CBS domain Aldo_ket_red PF00248.21 GAK67787.1 - 7.9e-62 209.1 0.0 9.3e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pept_tRNA_hydro PF01195.19 GAK67788.1 - 1.2e-23 84.0 0.0 6.5e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase Methyltransf_31 PF13847.6 GAK67788.1 - 1.7e-10 40.9 0.0 3.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK67788.1 - 2.3e-07 31.4 0.2 7.8e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAK67788.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 GAK67788.1 - 5e-05 22.7 0.0 8.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 GAK67788.1 - 0.0036 17.9 0.0 0.018 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 GAK67788.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 GAK67788.1 - 0.0094 15.4 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 GAK67788.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 GAK67788.1 - 0.033 14.9 0.0 0.096 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ATG13 PF10033.9 GAK67789.1 - 4.5e-65 219.7 0.0 6.6e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 Pkinase PF00069.25 GAK67791.1 - 3.2e-51 174.2 0.0 7.5e-51 173.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67791.1 - 5.9e-20 71.6 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK67791.1 - 0.0063 16.5 0.1 0.0063 16.5 0.1 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAK67791.1 - 0.015 14.9 0.2 0.034 13.7 0.2 1.6 1 0 0 1 1 1 0 RIO1 family FixO PF02433.15 GAK67791.1 - 9.9 5.5 7.9 26 4.2 7.9 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO PAC4 PF16093.5 GAK67793.1 - 0.0013 18.9 0.3 0.0019 18.3 0.3 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Ribosomal_S9 PF00380.19 GAK67794.1 - 7.2e-42 142.7 1.6 1e-41 142.2 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 RFX_DNA_binding PF02257.15 GAK67796.1 - 1.4e-22 80.1 0.0 3.1e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 GAK67796.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like PSK_trans_fac PF07704.11 GAK67796.1 - 0.27 12.0 2.1 0.74 10.6 1.0 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor NOA36 PF06524.12 GAK67798.1 - 0.00086 18.7 3.7 0.0017 17.8 3.7 1.5 1 0 0 1 1 1 1 NOA36 protein PTPRCAP PF15713.5 GAK67798.1 - 0.81 10.0 17.4 2.3 8.5 12.7 2.7 2 1 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 GAK67798.1 - 4.4 5.4 14.8 7.2 4.7 14.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GAK67798.1 - 6.9 6.5 10.1 17 5.2 10.1 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 GAK67798.1 - 8 6.5 8.1 14 5.7 6.9 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal BPL_LplA_LipB PF03099.19 GAK67799.1 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PPR_2 PF13041.6 GAK67799.1 - 0.021 15.0 0.0 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family PPR PF01535.20 GAK67799.1 - 0.13 12.6 0.0 21 5.6 0.0 3.9 5 0 0 5 5 5 0 PPR repeat DEAD PF00270.29 GAK67800.1 - 2.3e-40 138.2 0.0 4.2e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK67800.1 - 1e-19 70.9 0.0 3.4e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK67800.1 - 9.3e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAK67800.1 - 0.0061 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 GAK67800.1 - 0.019 15.3 0.5 0.46 10.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 GAK67800.1 - 0.23 10.6 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FXMRP1_C_core PF12235.8 GAK67800.1 - 1.5 9.5 7.0 4.4 8.0 7.0 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal CCDC53 PF10152.9 GAK67801.1 - 0.43 11.0 6.6 2.5 8.5 7.2 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AP-5_subunit_s1 PF15001.6 GAK67801.1 - 5.2 7.0 4.9 1.6 8.6 2.2 1.4 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Roughex PF06020.11 GAK67801.1 - 7.3 5.6 6.8 10 5.1 6.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein GWT1 PF06423.12 GAK67802.1 - 5e-38 130.6 0.0 1.2e-37 129.3 0.0 1.7 1 0 0 1 1 1 1 GWT1 IF-2B PF01008.17 GAK67804.1 - 2.1e-67 227.3 0.0 3e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1308 PF07000.11 GAK67804.1 - 0.012 15.5 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) MHYT PF03707.16 GAK67805.1 - 6e-15 55.1 19.9 4.9e-06 26.6 4.9 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Med14 PF08638.11 GAK67807.1 - 8.5e-52 175.4 0.1 1.5e-51 174.6 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkinase PF00069.25 GAK67808.1 - 2.1e-06 27.3 0.0 4.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 GAK67808.1 - 7.7e-05 22.6 4.8 3 8.3 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat Pkinase_Tyr PF07714.17 GAK67808.1 - 0.0098 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Vac14_Fab1_bd PF12755.7 GAK67808.1 - 0.12 13.0 0.0 5.6 7.6 0.0 2.6 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DnaJ PF00226.31 GAK67809.1 - 2.9e-13 49.7 1.2 2.9e-13 49.7 1.2 1.9 2 0 0 2 2 2 1 DnaJ domain eIF-3c_N PF05470.12 GAK67810.1 - 1.9e-179 597.8 17.0 1.9e-179 597.8 17.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GAK67810.1 - 2.3e-14 53.8 0.0 7.5e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 PCI domain GT-D PF08759.11 GAK67810.1 - 0.055 13.1 0.2 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase GT-D fold DUF2779 PF11074.8 GAK67810.1 - 0.06 13.8 6.0 4.7 7.7 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function(DUF2779) FeoC PF09012.10 GAK67810.1 - 0.072 13.2 0.1 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator CDC45 PF02724.14 GAK67810.1 - 1.4 7.1 15.5 2.9 6.1 15.5 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF4363 PF14276.6 GAK67810.1 - 4.5 7.4 6.6 11 6.1 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) OSCP PF00213.18 GAK67811.1 - 4e-36 124.7 2.8 4e-36 124.7 2.8 1.5 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit FAM27 PF15832.5 GAK67811.1 - 0.44 11.1 12.5 0.56 10.8 9.6 2.3 2 1 0 2 2 2 0 FAM27 D and E protein family GST_N PF02798.20 GAK67812.1 - 1e-10 41.8 0.0 2.2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK67812.1 - 2.9e-10 40.3 0.0 5.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAK67812.1 - 4.3e-10 39.9 0.0 8.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAK67812.1 - 4.6e-10 39.6 0.0 8.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAK67812.1 - 1.9e-07 31.0 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAK67812.1 - 3.3e-06 27.2 0.0 8.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.18 GAK67813.1 - 1.2e-54 185.3 0.0 1.7e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NUDE_C PF04880.13 GAK67814.1 - 1.3e-15 58.3 8.9 1.3e-15 58.3 8.9 6.1 4 2 1 6 6 4 1 NUDE protein, C-terminal conserved region CENP-F_leu_zip PF10473.9 GAK67814.1 - 4.1e-05 23.6 4.5 4.1e-05 23.6 4.5 2.5 3 0 0 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.9 GAK67814.1 - 0.00019 20.9 23.8 0.00074 19.0 12.4 2.1 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 GAK67814.1 - 0.0018 18.6 12.1 0.0018 18.6 12.1 4.1 3 1 2 5 5 4 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 GAK67814.1 - 0.0025 15.4 18.4 0.0036 14.9 18.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HIP1_clath_bdg PF16515.5 GAK67814.1 - 0.003 18.1 6.8 0.003 18.1 6.8 3.4 1 1 2 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_GP20 PF06810.11 GAK67814.1 - 0.003 17.4 5.4 0.003 17.4 5.4 3.2 1 1 2 3 3 3 1 Phage minor structural protein GP20 EzrA PF06160.12 GAK67814.1 - 0.0032 15.7 20.2 0.0056 14.9 20.2 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Filament PF00038.21 GAK67814.1 - 0.0032 17.1 9.1 0.0032 17.1 9.1 2.6 1 1 1 2 2 2 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 GAK67814.1 - 0.006 16.6 5.9 0.006 16.6 5.9 3.5 2 1 2 4 4 3 1 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 GAK67814.1 - 0.0082 16.2 10.3 0.0082 16.2 10.3 3.6 2 1 2 4 4 4 1 Designed helical repeat protein 10 domain PRKG1_interact PF15898.5 GAK67814.1 - 0.0097 16.8 26.7 0.023 15.6 12.7 2.9 3 0 0 3 3 2 1 cGMP-dependent protein kinase interacting domain HTH_Tnp_1 PF01527.20 GAK67814.1 - 0.043 14.1 0.6 0.043 14.1 0.6 3.5 3 1 1 4 4 3 0 Transposase Prefoldin_2 PF01920.20 GAK67814.1 - 0.059 13.3 25.7 6.4 6.8 4.2 4.3 2 1 1 3 3 3 0 Prefoldin subunit HOOK PF05622.12 GAK67814.1 - 0.095 10.8 25.0 0.2 9.8 25.0 1.4 1 1 0 1 1 1 0 HOOK protein PSII_Pbs27 PF13326.6 GAK67814.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.3 2 0 0 2 2 1 0 Photosystem II Pbs27 Syntaxin-6_N PF09177.11 GAK67814.1 - 0.19 12.3 22.5 0.086 13.4 7.4 3.7 2 1 2 4 4 3 0 Syntaxin 6, N-terminal Rab5-bind PF09311.11 GAK67814.1 - 0.21 11.0 22.8 2.6 7.4 22.5 2.0 1 1 0 1 1 1 0 Rabaptin-like protein Lebercilin PF15619.6 GAK67814.1 - 0.26 10.9 27.5 0.066 12.9 8.3 3.5 2 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DMPK_coil PF08826.10 GAK67814.1 - 0.27 11.4 22.2 0.12 12.5 1.8 3.7 3 0 0 3 3 3 0 DMPK coiled coil domain like Mating_N PF12731.7 GAK67814.1 - 0.34 11.0 5.2 0.36 10.9 0.6 2.5 1 1 1 2 2 2 0 Mating-type protein beta 1 FAM184 PF15665.5 GAK67814.1 - 0.38 10.5 25.8 21 4.8 23.1 2.8 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Stn1 PF10451.9 GAK67814.1 - 0.43 9.5 2.0 0.73 8.8 2.0 1.4 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DivIC PF04977.15 GAK67814.1 - 0.46 10.3 13.5 0.58 10.0 0.2 3.7 2 1 1 3 3 3 0 Septum formation initiator CCDC-167 PF15188.6 GAK67814.1 - 0.64 10.4 25.2 4.3 7.8 13.7 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Bacillus_HBL PF05791.11 GAK67814.1 - 0.66 9.8 8.3 0.066 13.0 3.4 1.8 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.6 GAK67814.1 - 0.78 8.3 13.2 1.5 7.4 13.2 1.4 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 GAK67814.1 - 0.92 9.9 26.7 1.2 9.5 12.3 2.4 2 1 1 3 3 2 0 Fez1 SlyX PF04102.12 GAK67814.1 - 0.94 10.1 17.2 1.7 9.3 1.6 5.1 3 1 2 5 5 5 0 SlyX TACC_C PF05010.14 GAK67814.1 - 1.3 8.7 21.1 7.5 6.3 21.1 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YscO PF07321.12 GAK67814.1 - 1.3 8.9 18.4 0.59 10.1 6.7 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO HALZ PF02183.18 GAK67814.1 - 1.4 9.2 5.9 0.86 9.9 1.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Laminin_II PF06009.12 GAK67814.1 - 1.6 8.7 15.5 0.04 13.9 4.9 2.6 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 GAK67814.1 - 1.9 8.8 19.2 0.38 11.1 4.0 3.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERM PF00769.19 GAK67814.1 - 1.9 8.2 35.4 0.057 13.2 9.9 2.6 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Prominin PF05478.11 GAK67814.1 - 2 6.3 9.3 4 5.3 9.3 1.5 1 0 0 1 1 1 0 Prominin ZapB PF06005.12 GAK67814.1 - 2.3 8.7 30.7 0.098 13.1 8.6 4.0 2 1 1 3 3 1 0 Cell division protein ZapB UPF0242 PF06785.11 GAK67814.1 - 2.4 8.2 26.6 0.13 12.4 13.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 GAK67814.1 - 2.4 8.2 7.3 3 7.9 2.1 2.6 2 1 2 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GAK67814.1 - 2.6 8.6 6.9 5 7.7 0.2 3.1 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 GAK67814.1 - 2.9 7.3 32.2 0.61 9.5 2.7 2.6 2 1 1 3 3 2 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 GAK67814.1 - 3.2 7.1 26.1 0.46 9.9 13.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 RasGAP_C PF03836.15 GAK67814.1 - 3.3 7.9 10.8 57 3.8 10.7 2.8 1 1 0 1 1 1 0 RasGAP C-terminus DUF4407 PF14362.6 GAK67814.1 - 3.8 6.8 16.4 1.8 7.8 12.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 GAK67814.1 - 4.7 6.2 19.6 0.42 9.7 10.3 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 COMP PF11598.8 GAK67814.1 - 7.8 7.1 9.6 0.23 12.0 1.9 2.3 3 0 0 3 3 1 0 Cartilage oligomeric matrix protein DUF948 PF06103.11 GAK67814.1 - 7.9 6.8 11.0 2.2 8.6 0.5 3.9 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 GAK67814.1 - 8.2 6.9 20.9 6.1 7.3 0.8 5.2 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 GAK67814.1 - 8.2 7.0 32.8 2.5 8.6 16.5 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region CLASP_N PF12348.8 GAK67815.1 - 1.8e-22 80.1 0.0 2.8e-06 27.1 0.0 4.9 4 1 0 4 4 4 4 CLASP N terminal HEAT PF02985.22 GAK67815.1 - 4.2e-16 57.7 22.7 0.015 15.5 0.1 9.9 10 0 0 10 10 10 4 HEAT repeat Cnd1 PF12717.7 GAK67815.1 - 1.3e-13 51.4 4.0 0.15 12.1 0.0 7.4 6 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAK67815.1 - 2.6e-11 43.8 18.3 0.039 14.4 0.0 7.8 6 2 1 7 7 6 4 HEAT repeats Adaptin_N PF01602.20 GAK67815.1 - 7.7e-08 31.3 1.0 0.015 13.9 0.0 5.1 5 1 0 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 GAK67815.1 - 0.00015 22.3 0.0 22 5.7 0.0 6.1 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region DCB PF16213.5 GAK67815.1 - 0.0023 17.6 0.4 1.5 8.5 0.0 3.6 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Proteasom_PSMB PF10508.9 GAK67815.1 - 0.0059 15.2 0.0 0.61 8.5 0.0 2.6 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 GAK67815.1 - 0.0093 16.5 22.1 0.49 11.0 0.0 7.2 7 0 0 7 7 6 2 HEAT-like repeat RTP1_C1 PF10363.9 GAK67815.1 - 0.029 14.5 4.8 11 6.2 0.0 5.9 9 0 0 9 9 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GAK67815.1 - 0.15 12.2 8.4 0.42 10.7 0.1 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 GAK67815.1 - 0.49 9.5 4.0 11 5.1 0.0 4.4 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) Glycos_transf_2 PF00535.26 GAK67816.1 - 1.1e-27 97.0 0.0 1.4e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAK67816.1 - 1.1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyoxalase PF00903.25 GAK67817.1 - 4.1e-23 82.0 0.2 5.5e-23 81.5 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAK67817.1 - 4e-08 33.5 0.0 6.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAK67817.1 - 3.1e-06 27.9 0.0 5.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 GAK67817.1 - 4.5e-05 23.6 0.0 0.028 14.5 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 GAK67817.1 - 7e-05 22.7 0.2 0.00031 20.7 0.2 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Peptidase_M20 PF01546.28 GAK67818.1 - 2.1e-23 83.1 0.1 4e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 GAK67818.1 - 5.6e-22 77.6 7.8 2.2e-05 25.1 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat M20_dimer PF07687.14 GAK67818.1 - 6.2e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.11 GAK67818.1 - 2.5e-05 23.2 0.1 0.019 13.7 0.0 3.5 2 2 1 3 3 3 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 GAK67818.1 - 0.0048 17.2 0.1 9.2 6.6 0.0 3.9 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 GAK67818.1 - 0.044 13.5 1.2 0.08 12.7 1.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nup160 PF11715.8 GAK67818.1 - 0.081 11.5 1.1 4.3 5.9 0.1 3.3 3 1 1 4 4 4 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 GAK67818.1 - 0.13 11.1 0.1 0.39 9.6 0.0 1.7 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DUF3246 PF11596.8 GAK67818.1 - 0.2 11.0 6.4 0.5 9.8 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SR-25 PF10500.9 GAK67818.1 - 5.1 6.6 9.2 13 5.3 9.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpc34 PF05158.12 GAK67819.1 - 3.4e-78 263.4 0.2 3.3e-69 233.8 0.0 2.3 2 1 0 2 2 2 2 RNA polymerase Rpc34 subunit TrmB PF01978.19 GAK67819.1 - 0.0063 16.4 0.7 0.038 13.9 0.1 2.5 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 GAK67819.1 - 0.014 15.6 0.3 0.045 13.9 0.3 1.8 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MarR PF01047.22 GAK67819.1 - 0.029 14.3 0.1 0.07 13.1 0.1 1.7 1 0 0 1 1 1 0 MarR family Lin-8 PF03353.15 GAK67819.1 - 0.029 13.9 12.7 0.059 12.9 12.7 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 GAK67819.1 - 0.24 8.5 12.8 0.32 8.0 12.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Penicillinase_R PF03965.16 GAK67819.1 - 0.27 11.6 1.6 4.6 7.6 0.1 2.5 1 1 1 2 2 2 0 Penicillinase repressor Glyco_hydro_45 PF02015.16 GAK67822.1 - 2.6e-102 341.2 14.6 3.6e-102 340.7 14.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 FAD_binding_3 PF01494.19 GAK67823.1 - 1.9e-21 76.7 0.6 1.3e-18 67.4 0.6 3.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAK67823.1 - 1.9e-06 28.4 0.0 1.2e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAK67823.1 - 3.4e-05 23.2 0.0 6.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAK67823.1 - 7.3e-05 22.9 0.2 0.00023 21.3 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK67823.1 - 0.00012 21.8 0.1 0.00023 20.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAK67823.1 - 0.00042 19.1 0.0 0.0012 17.6 0.0 1.8 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 GAK67823.1 - 0.0022 17.1 0.1 0.0041 16.2 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAK67823.1 - 0.0049 16.8 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 GAK67823.1 - 0.075 12.1 0.0 0.075 12.1 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain HEPN_Swt1 PF18731.1 GAK67823.1 - 0.11 12.8 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Swt1-like HEPN SE PF08491.10 GAK67823.1 - 0.12 11.4 0.0 0.61 9.1 0.0 2.2 2 1 1 3 3 3 0 Squalene epoxidase NAD_binding_7 PF13241.6 GAK67823.1 - 0.14 12.6 0.0 0.53 10.8 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 GAK67824.1 - 0.032 13.7 0.2 0.035 13.5 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Acyl_transf_3 PF01757.22 GAK67825.1 - 1.5e-36 126.2 28.7 1.5e-36 126.2 28.7 3.1 3 0 0 3 3 3 1 Acyltransferase family Glyco_trans_2_3 PF13632.6 GAK67825.1 - 1.6e-29 103.2 2.4 1.6e-29 103.2 2.4 3.9 3 1 1 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAK67825.1 - 1e-12 48.4 0.0 1.7e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fumarate_red_C PF02300.17 GAK67827.1 - 0.46 10.6 4.1 1.3 9.1 4.1 1.7 1 0 0 1 1 1 0 Fumarate reductase subunit C Cellulase PF00150.18 GAK67828.1 - 0.00028 20.4 0.1 0.67 9.3 0.0 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Rota_VP4_MID PF17477.2 GAK67828.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain Pkinase PF00069.25 GAK67829.1 - 2.7e-48 164.6 0.0 5.3e-48 163.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67829.1 - 3.8e-28 98.5 0.0 5.1e-23 81.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.25 GAK67830.1 - 2.3e-16 59.6 0.2 3.6e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain PI3_PI4_kinase PF00454.27 GAK67831.1 - 3.5e-33 115.5 0.0 1.2e-32 113.7 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Jun PF03957.13 GAK67831.1 - 0.64 9.9 5.2 0.51 10.2 0.4 2.9 3 1 0 3 3 3 0 Jun-like transcription factor Pkinase PF00069.25 GAK67832.1 - 3.5e-31 108.6 0.0 6.2e-25 88.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67832.1 - 1.1e-16 61.0 0.0 7.8e-14 51.6 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK67832.1 - 9.7e-05 21.8 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAK67832.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pex16 PF08610.10 GAK67833.1 - 3.5e-116 387.9 0.0 5e-116 387.4 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pkinase PF00069.25 GAK67834.1 - 2.2e-60 204.3 0.0 2.9e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK67834.1 - 1.3e-39 136.0 0.0 2.2e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK67834.1 - 2.8e-05 23.6 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAK67834.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAK67834.1 - 0.0082 16.1 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAK67834.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TMEM213 PF15192.6 GAK67834.1 - 0.13 12.3 0.6 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 TMEM213 family MmgE_PrpD PF03972.14 GAK67835.1 - 6.2e-148 493.0 0.1 8.2e-148 492.6 0.1 1.1 1 0 0 1 1 1 1 MmgE/PrpD family PALP PF00291.25 GAK67836.1 - 4.3e-69 233.2 0.1 5.3e-69 232.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3425 PF11905.8 GAK67837.1 - 1.6e-08 34.5 0.0 3.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PPR_3 PF13812.6 GAK67838.1 - 1.1e-12 47.8 0.5 8.2e-05 22.6 0.0 6.3 5 2 2 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAK67838.1 - 2.6e-11 43.5 0.0 0.00012 22.2 0.0 6.1 6 1 2 8 8 8 3 PPR repeat family PPR PF01535.20 GAK67838.1 - 1.2e-05 25.2 1.5 31 5.1 0.0 6.5 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 GAK67838.1 - 7.4e-05 22.2 0.0 0.0014 18.0 0.0 2.7 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP HrpB1_HrpK PF09613.10 GAK67838.1 - 0.0033 17.1 0.0 0.32 10.6 0.0 2.7 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) KH_1 PF00013.29 GAK67839.1 - 5.6e-94 308.0 23.2 2.9e-12 46.2 1.6 15.7 16 0 0 16 16 16 11 KH domain KH_2 PF07650.17 GAK67839.1 - 3.2e-16 58.9 18.3 0.012 15.4 0.7 9.7 8 1 0 9 9 9 5 KH domain KH_4 PF13083.6 GAK67839.1 - 1.1e-07 31.6 21.0 0.073 13.0 0.0 8.2 7 1 2 9 9 9 3 KH domain SLS PF14611.6 GAK67839.1 - 2e-06 27.8 17.2 0.048 13.5 0.3 6.8 7 1 0 7 7 7 3 Mitochondrial inner-membrane-bound regulator Phytoreo_P8 PF07124.11 GAK67839.1 - 0.013 14.5 0.6 0.024 13.6 0.6 1.3 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 SCO1-SenC PF02630.14 GAK67839.1 - 0.034 14.1 0.7 2.2 8.2 0.0 3.6 4 0 0 4 4 4 0 SCO1/SenC DUF3708 PF12501.8 GAK67839.1 - 0.11 12.3 0.2 0.5 10.1 0.2 2.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter MOEP19 PF16005.5 GAK67839.1 - 0.19 11.7 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 KH-like RNA-binding domain KH_5 PF13184.6 GAK67839.1 - 0.2 11.8 9.2 2.5 8.3 0.0 5.5 6 0 0 6 6 6 0 NusA-like KH domain YbbR PF07949.12 GAK67839.1 - 3.6 8.0 15.1 18 5.8 0.1 6.7 7 0 0 7 7 7 0 YbbR-like protein DUF4112 PF13430.6 GAK67840.1 - 1.9e-30 105.2 1.0 5.6e-30 103.7 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MFS_1 PF07690.16 GAK67840.1 - 1e-19 70.7 43.3 1.9e-13 50.1 23.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 GAK67840.1 - 0.0096 14.3 5.8 0.86 7.8 0.0 2.5 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF4786 PF16027.5 GAK67840.1 - 0.034 14.7 4.1 0.065 13.8 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) SelP_N PF04592.14 GAK67840.1 - 8 5.8 22.7 20 4.5 22.7 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UBN_AB PF14075.6 GAK67842.1 - 2.3e-44 151.7 0.9 2.3e-44 151.7 0.9 2.0 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 GAK67842.1 - 4.3e-13 49.0 2.2 4.3e-13 49.0 2.2 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain CDC45 PF02724.14 GAK67842.1 - 5.9 5.1 20.1 0.005 15.2 5.4 2.2 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.12 GAK67842.1 - 7 5.9 16.1 17 4.6 16.1 1.6 1 0 0 1 1 1 0 NOA36 protein DUF815 PF05673.13 GAK67843.1 - 0.011 14.9 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NMD3 PF04981.13 GAK67844.1 - 1.2e-84 283.6 3.2 1.7e-84 283.1 3.2 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 GAK67844.1 - 0.0024 17.9 5.9 0.32 11.0 5.9 2.9 1 1 0 1 1 1 1 Double zinc ribbon Skp1 PF01466.19 GAK67844.1 - 0.11 12.6 2.4 0.26 11.4 2.4 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DUF5321 PF17254.2 GAK67844.1 - 0.24 10.8 3.4 0.62 9.5 3.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5321) DUF2340 PF10209.9 GAK67845.1 - 6.6e-48 162.1 0.7 8.4e-48 161.8 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Whi5 PF08528.11 GAK67848.1 - 1.6e-10 40.3 0.0 2.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like TRAPP PF04051.16 GAK67849.1 - 2.2e-40 137.7 0.0 2.9e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Haemagg_act PF05860.13 GAK67849.1 - 0.039 13.8 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 haemagglutination activity domain dsDNA_bind PF01984.20 GAK67850.1 - 1.5e-35 121.8 0.5 1.9e-35 121.5 0.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Steroid_dh PF02544.16 GAK67851.1 - 1.3e-25 90.1 6.2 3.6e-19 69.2 6.3 4.4 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 GAK67851.1 - 0.00027 20.5 0.3 0.00048 19.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) FKBP_C PF00254.28 GAK67852.1 - 6.5e-29 100.1 0.0 1.3e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase JmjC PF02373.22 GAK67852.1 - 3.7e-15 56.3 0.0 1.2e-14 54.7 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAK67852.1 - 0.0018 18.1 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Cupin-like domain FYVE PF01363.21 GAK67852.1 - 0.17 12.0 12.4 0.19 11.9 8.1 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-B_box PF00643.24 GAK67852.1 - 1.2 9.4 8.3 3 8.1 8.3 1.6 1 0 0 1 1 1 0 B-box zinc finger CEBP_ZZ PF16366.5 GAK67852.1 - 1.3 9.3 8.2 3.4 8.0 8.2 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Nse4-Nse3_bdg PF15412.6 GAK67852.1 - 3.5 7.8 4.4 0.52 10.5 0.1 1.9 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE MAGI_u1 PF16663.5 GAK67853.1 - 0.42 10.7 3.9 1.8 8.7 3.9 2.1 1 0 0 1 1 1 0 Unstructured region on MAGI DUF4100 PF13352.6 GAK67853.1 - 4 7.1 8.3 0.069 12.9 0.5 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4100) Maf1 PF09174.10 GAK67855.1 - 3.9e-38 131.3 0.0 2.3e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator TruD PF01142.18 GAK67856.1 - 1.2e-69 235.2 0.0 3e-65 220.7 0.0 3.9 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) OPT PF03169.15 GAK67857.1 - 2.2e-153 512.1 47.7 2.6e-153 511.9 47.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FA_hydroxylase PF04116.13 GAK67858.1 - 1.5e-23 83.6 9.8 1.5e-23 83.6 9.8 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Glyco_hydro_3_C PF01915.22 GAK67859.1 - 1.2e-47 162.6 0.1 1.8e-47 162.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAK67859.1 - 1.1e-32 113.7 0.0 1.4e-31 110.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAK67859.1 - 1.1e-18 67.1 0.1 2.6e-18 65.9 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PGAP1 PF07819.13 GAK67860.1 - 1.1e-58 198.8 0.0 1.5e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 GAK67860.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 GAK67860.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2894 PF11445.8 GAK67862.1 - 0.8 10.1 5.9 2.9 8.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) CENP-O PF09496.10 GAK67864.1 - 0.17 11.9 1.0 0.41 10.6 1.0 1.7 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component GvpO PF05800.11 GAK67865.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO His_Phos_2 PF00328.22 GAK67867.1 - 6.6e-74 249.5 0.0 9e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GAK67867.1 - 4.5e-39 132.5 0.0 9.5e-39 131.5 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAK67867.1 - 1.6e-05 24.6 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TspO_MBR PF03073.15 GAK67868.1 - 4.9e-46 156.1 9.0 5.6e-46 155.9 9.0 1.0 1 0 0 1 1 1 1 TspO/MBR family AMMECR1 PF01871.17 GAK67869.1 - 1.3e-42 145.3 0.0 5.3e-42 143.2 0.0 1.8 1 1 0 1 1 1 1 AMMECR1 AhpC-TSA PF00578.21 GAK67870.1 - 1.3e-29 102.7 0.0 2.1e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAK67870.1 - 7.1e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAK67870.1 - 1.8e-09 37.3 0.0 3.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ras PF00071.22 GAK67872.1 - 4.4e-43 146.7 0.2 8.6e-41 139.2 0.1 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAK67872.1 - 5.1e-32 110.6 0.1 9.3e-32 109.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK67872.1 - 2.6e-11 43.3 0.1 5.3e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAK67872.1 - 6.9e-06 26.1 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAK67872.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAK67872.1 - 0.048 13.0 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAK67872.1 - 0.18 11.7 0.1 0.51 10.2 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 GAK67873.1 - 1.3e-103 344.9 0.0 1.9e-103 344.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAK67873.1 - 2.4e-30 105.0 0.1 4.1e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAK67873.1 - 2.4e-20 72.8 0.0 1e-19 70.7 0.0 2.2 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAK67873.1 - 8.7e-14 52.0 0.7 2.7e-13 50.4 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 GAK67873.1 - 2.6e-08 33.9 0.0 2.2e-06 27.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAK67873.1 - 2.4e-07 30.4 0.0 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAK67873.1 - 0.01 15.7 0.1 0.046 13.6 0.1 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAK67873.1 - 0.15 11.8 0.1 0.88 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain SLAC1 PF03595.17 GAK67874.1 - 1.1e-72 245.0 44.6 1.3e-72 244.8 44.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Acyl-CoA_dh_1 PF00441.24 GAK67875.1 - 2.5e-27 95.9 4.4 3.8e-27 95.3 4.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAK67875.1 - 7.8e-19 67.7 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAK67875.1 - 1.4e-10 41.8 0.0 2.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAK67875.1 - 1.8e-10 41.2 4.7 3.3e-10 40.3 4.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAK67875.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal WLM PF08325.10 GAK67876.1 - 1.1e-27 97.4 0.5 8.5e-27 94.5 0.5 2.1 1 1 0 1 1 1 1 WLM domain ubiquitin PF00240.23 GAK67876.1 - 0.00089 19.0 0.1 0.0043 16.8 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF45 PF01863.17 GAK67876.1 - 0.033 14.2 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF45 C2 PF00168.30 GAK67877.1 - 2.8e-12 46.8 0.0 7.2e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain cwf21 PF08312.12 GAK67878.1 - 2e-14 53.5 11.2 2e-14 53.5 11.2 2.7 3 0 0 3 3 3 1 cwf21 domain Ribonuclease_3 PF00636.26 GAK67879.1 - 2.2e-31 108.6 0.0 8.3e-17 61.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 GAK67879.1 - 1.2e-20 73.4 0.1 4e-20 71.8 0.1 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 GAK67879.1 - 9.4e-18 64.6 0.7 4.2e-09 36.6 0.0 3.8 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 GAK67879.1 - 8.4e-13 48.6 0.0 1.9e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK67879.1 - 2.5e-09 37.2 0.0 6.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAK67879.1 - 3.5e-08 33.6 0.0 5.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 GAK67879.1 - 0.0017 19.0 0.0 0.004 17.8 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif SWI2_SNF2 PF18766.1 GAK67879.1 - 0.19 11.4 0.0 1.3 8.6 0.0 2.0 1 1 0 1 1 1 0 SWI2/SNF2 ATPase RAP1 PF07218.11 GAK67880.1 - 6.7 4.9 9.3 13 3.9 9.3 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Not3 PF04065.15 GAK67881.1 - 9e-89 296.9 24.7 1.7e-88 295.9 24.7 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GAK67881.1 - 9.6e-46 155.1 10.4 2.7e-45 153.7 10.4 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 GAK67881.1 - 0.0063 16.3 3.7 0.016 15.0 3.7 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) IL11 PF07400.11 GAK67881.1 - 0.034 13.8 1.7 0.088 12.4 1.7 1.7 1 0 0 1 1 1 0 Interleukin 11 Syntaxin_2 PF14523.6 GAK67881.1 - 8.3 6.9 16.0 0.076 13.4 3.9 3.2 4 0 0 4 4 4 0 Syntaxin-like protein COX15-CtaA PF02628.15 GAK67882.1 - 1.8e-90 303.3 15.1 5.5e-90 301.7 15.1 1.8 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_L19 PF01245.20 GAK67882.1 - 3.3e-15 56.0 0.1 5.7e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 MFS_1 PF07690.16 GAK67883.1 - 4.8e-29 101.4 35.3 3.2e-26 92.1 15.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK67883.1 - 4.4e-16 58.8 1.6 4.4e-16 58.8 1.6 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 GAK67883.1 - 0.00019 20.8 1.5 0.00019 20.8 1.5 2.6 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Wzy_C PF04932.15 GAK67883.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.5 2 1 0 2 2 2 0 O-Antigen ligase DUF2157 PF09925.9 GAK67883.1 - 1.8 8.3 13.3 3.3 7.5 0.8 3.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) SIP1 PF04938.12 GAK67884.1 - 3.8e-27 95.4 0.0 6.6e-27 94.7 0.0 1.3 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TFIID-31kDa PF02291.15 GAK67885.1 - 3.6e-41 140.1 0.2 8e-40 135.7 0.2 2.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_S14 PF00253.21 GAK67885.1 - 8.2e-23 79.9 0.2 1.7e-22 78.9 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Bromo_TP PF07524.13 GAK67885.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated SF1-HH PF16275.5 GAK67886.1 - 4.1e-38 130.2 0.6 7.8e-38 129.3 0.6 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 GAK67886.1 - 5.5e-11 42.0 11.7 1.8e-05 24.6 2.0 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 GAK67886.1 - 3.3e-08 33.2 0.1 5.7e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 GAK67886.1 - 7.5e-07 29.0 10.8 0.00038 20.3 3.0 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GAK67886.1 - 0.0022 17.8 12.3 0.17 11.8 3.8 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 GAK67886.1 - 6.7 6.5 10.5 2.6 7.8 2.7 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger ABC_tran PF00005.27 GAK67887.1 - 4.4e-47 160.0 0.0 6.3e-26 91.5 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAK67887.1 - 4.5e-15 56.2 0.4 0.026 14.3 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAK67887.1 - 7e-12 45.2 0.0 0.00049 19.6 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 GAK67887.1 - 2e-09 37.2 0.7 4.1e-09 36.2 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 GAK67887.1 - 1.6e-06 28.8 3.7 0.02 15.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 GAK67887.1 - 4e-06 26.5 0.5 0.063 13.0 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAK67887.1 - 1.4e-05 25.1 0.8 0.014 15.4 0.0 3.4 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 GAK67887.1 - 6.6e-05 23.2 0.6 0.13 12.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 GAK67887.1 - 0.00042 20.6 0.4 1.9 8.7 0.0 4.1 4 1 1 5 5 5 1 AAA domain DUF87 PF01935.17 GAK67887.1 - 0.00074 19.7 0.1 0.25 11.4 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 GAK67887.1 - 0.0018 18.2 0.3 0.052 13.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 GAK67887.1 - 0.0025 17.5 0.4 1.9 8.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 GAK67887.1 - 0.0041 16.2 1.1 0.51 9.3 0.1 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAK67887.1 - 0.0043 17.4 1.0 2.1 8.7 0.0 3.9 3 1 1 4 4 4 1 AAA ATPase domain Tudor-knot PF11717.8 GAK67887.1 - 0.0056 16.6 0.6 0.012 15.4 0.6 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_18 PF13238.6 GAK67887.1 - 0.0062 17.1 0.1 2.3 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAK67887.1 - 0.028 14.1 0.0 7.4 6.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain CLASP_N PF12348.8 GAK67887.1 - 0.03 13.9 0.0 15 5.1 0.0 3.5 3 0 0 3 3 3 0 CLASP N terminal AAA_15 PF13175.6 GAK67887.1 - 0.1 12.3 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 GAK67887.1 - 0.1 12.2 0.1 13 5.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAK67887.1 - 0.12 12.6 0.0 8.2 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ALF PF03752.13 GAK67887.1 - 0.13 12.3 3.6 15 5.7 0.2 3.3 2 1 0 2 2 2 0 Short repeats of unknown function Dynamin_N PF00350.23 GAK67887.1 - 0.14 12.2 0.1 0.96 9.5 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 GAK67887.1 - 0.14 12.5 0.0 7.7 7.0 0.0 3.4 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.12 GAK67887.1 - 0.16 11.9 0.1 21 5.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain HEAT_EZ PF13513.6 GAK67887.1 - 0.18 12.3 7.9 17 6.1 0.0 5.2 5 2 2 7 7 5 0 HEAT-like repeat cobW PF02492.19 GAK67887.1 - 0.22 11.1 1.3 14 5.2 0.0 3.3 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF3720 PF12517.8 GAK67887.1 - 0.42 11.6 4.4 1.8 9.6 4.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) ABC_tran_Xtn PF12848.7 GAK67887.1 - 3.1 7.9 8.1 0.11 12.5 0.4 2.5 2 0 0 2 2 1 0 ABC transporter TRAPPC9-Trs120 PF08626.11 GAK67889.1 - 2e-158 529.0 0.0 2.9e-158 528.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GATA PF00320.27 GAK67889.1 - 2.2e-17 62.3 1.9 4.3e-17 61.4 1.9 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 GAK67889.1 - 9.1e-13 47.8 1.3 1.8e-12 46.9 1.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF155 PF02582.14 GAK67890.1 - 1.4e-49 168.5 0.0 2.3e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ank_2 PF12796.7 GAK67891.1 - 7.6e-26 90.5 0.1 3.5e-13 49.9 0.0 3.2 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAK67891.1 - 4.6e-19 68.5 3.7 3.2e-07 30.8 0.2 5.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAK67891.1 - 7.4e-19 67.6 2.3 2.7e-06 27.5 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAK67891.1 - 2e-16 59.6 4.6 0.00097 19.5 0.2 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 GAK67891.1 - 4.6e-16 57.3 1.4 0.00029 21.1 0.1 5.1 4 0 0 4 4 4 4 Ankyrin repeat DHHC PF01529.20 GAK67891.1 - 6.1e-10 39.3 2.0 1.6e-07 31.5 0.1 2.6 1 1 1 2 2 2 2 DHHC palmitoyltransferase HisKA_7TM PF16927.5 GAK67891.1 - 1.7 8.7 10.6 0.22 11.5 2.4 2.5 2 1 0 2 2 2 0 N-terminal 7TM region of histidine kinase Adaptin_N PF01602.20 GAK67892.1 - 1.6e-125 419.7 10.9 1.9e-125 419.4 10.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAK67892.1 - 1.5e-58 197.4 1.8 1.5e-58 197.4 1.8 2.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAK67892.1 - 1.7e-14 54.0 7.9 5.5e-07 29.9 0.4 4.7 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.22 GAK67892.1 - 1.3e-09 37.5 1.3 0.021 15.1 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat Cnd3 PF12719.7 GAK67892.1 - 7.1e-06 25.4 0.3 0.021 14.0 0.0 2.5 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 GAK67892.1 - 0.00011 21.9 0.2 2.6 7.6 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 GAK67892.1 - 0.00092 19.7 2.2 6 7.5 0.1 4.6 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 GAK67892.1 - 0.0017 18.4 3.4 0.91 9.7 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 GAK67892.1 - 0.021 14.3 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Armadillo-like RasGEF_N_2 PF14663.6 GAK67892.1 - 0.35 11.3 2.8 4 7.9 0.1 3.3 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Collagen PF01391.18 GAK67893.1 - 3.2 7.6 13.5 2.5e+02 1.5 13.5 2.5 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) COesterase PF00135.28 GAK67894.1 - 9.3e-93 311.8 0.0 1.2e-92 311.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAK67894.1 - 2.3e-11 44.0 0.2 4.1e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAK67894.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Spike_torovirin PF17072.5 GAK67894.1 - 0.024 11.8 0.0 0.034 11.3 0.0 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein MIF4G PF02854.19 GAK67896.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain BORCS6 PF10157.9 GAK67896.1 - 0.083 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Ribosomal_S21 PF01165.20 GAK67897.1 - 7.1e-12 44.9 5.3 1.1e-11 44.3 5.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Pheromone PF08015.11 GAK67897.1 - 1.1 10.4 5.8 0.42 11.7 3.1 1.8 2 1 0 2 2 2 0 Fungal mating-type pheromone Fungal_trans PF04082.18 GAK67899.1 - 5.2e-21 74.9 0.0 8.3e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK67899.1 - 1.8e-09 37.6 1.5 3.5e-09 36.6 1.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Solute_trans_a PF03619.16 GAK67901.1 - 2.1e-89 299.6 12.8 2.6e-89 299.3 12.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha eIF-1a PF01176.19 GAK67902.1 - 9.4e-22 76.6 0.0 1.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Cwf_Cwc_15 PF04889.12 GAK67902.1 - 0.056 13.2 6.6 0.059 13.1 6.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sugar_tr PF00083.24 GAK67903.1 - 2.4e-111 372.8 20.3 2.9e-111 372.5 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK67903.1 - 8.6e-24 84.1 26.7 8.6e-24 84.1 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAK67903.1 - 8.2e-06 24.5 0.5 1.9e-05 23.3 0.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 GAK67903.1 - 0.00019 20.5 2.1 0.00043 19.3 2.1 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 GAK67903.1 - 0.005 15.3 0.2 0.0083 14.6 0.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector zf-CCCH PF00642.24 GAK67904.1 - 5.4e-13 48.5 14.9 1.2e-06 28.3 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAK67904.1 - 0.0038 17.2 10.9 0.008 16.2 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Phos_pyr_kin PF08543.12 GAK67904.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase zf-CCCH_3 PF15663.5 GAK67904.1 - 0.47 10.7 8.6 0.3 11.3 2.5 2.3 2 0 0 2 2 2 0 Zinc-finger containing family DEAD PF00270.29 GAK67905.1 - 2.4e-36 125.1 0.0 3.5e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK67905.1 - 2.8e-29 101.7 0.0 9.3e-29 100.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK67905.1 - 0.00063 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rxt3 PF08642.10 GAK67906.1 - 1.6e-20 74.1 4.3 2.6e-20 73.5 0.0 3.0 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 GAK67906.1 - 0.062 13.4 0.0 0.86 9.8 0.0 2.2 2 0 0 2 2 2 0 LCCL domain ESCRT-II PF05871.12 GAK67907.1 - 8.3e-48 162.2 0.0 1.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit UPRTase PF14681.6 GAK67908.1 - 5.3e-79 264.5 0.0 6.1e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAK67908.1 - 9.2e-05 22.0 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C2H2_9 PF16293.5 GAK67909.1 - 0.0024 17.7 1.6 1.9 8.4 0.1 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 GAK67909.1 - 0.024 15.0 0.4 5.5 7.4 0.1 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAK67909.1 - 0.035 15.0 2.3 2.7 9.0 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger PSCyt3 PF07627.11 GAK67909.1 - 0.067 13.5 0.2 0.25 11.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zinc_ribbon_4 PF13717.6 GAK67909.1 - 0.52 10.3 3.9 3.5 7.6 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 GAK67909.1 - 5.9 7.5 7.8 3.5 8.3 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type LSM PF01423.22 GAK67910.1 - 1.9e-17 62.7 0.0 3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.16 GAK67911.1 - 1.8e-27 96.2 26.8 1.8e-27 96.2 26.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK67911.1 - 6.5e-13 48.3 2.8 6.5e-13 48.3 2.8 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 GAK67911.1 - 0.002 16.5 0.1 0.0059 15.0 0.1 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Hydrolase_4 PF12146.8 GAK67913.1 - 1.3e-11 44.2 0.0 4.4e-08 32.7 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 GAK67913.1 - 7.9e-10 37.9 0.1 6.6e-09 34.9 0.0 2.2 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 GAK67913.1 - 1.2e-09 38.2 0.1 5.5e-07 29.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAK67913.1 - 1.3e-08 34.8 0.0 1.4e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 GAK67913.1 - 4.8e-08 32.7 0.0 9.2e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAK67913.1 - 5.2e-08 33.8 0.8 7.4e-08 33.3 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAK67913.1 - 1.3e-06 28.1 0.0 3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 GAK67913.1 - 3.9e-06 27.0 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 GAK67913.1 - 6e-05 21.7 0.3 0.21 10.1 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 GAK67913.1 - 0.004 17.0 0.0 0.019 14.8 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 GAK67913.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) COesterase PF00135.28 GAK67913.1 - 0.085 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family BRCT_2 PF16589.5 GAK67914.1 - 7.1e-21 74.4 0.0 0.013 15.9 0.0 6.7 7 0 0 7 7 7 5 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAK67914.1 - 2e-18 66.1 4.0 6.1e-14 51.7 0.1 5.2 6 0 0 6 6 6 3 twin BRCT domain BRCT PF00533.26 GAK67914.1 - 3.6e-15 56.1 0.0 1.8e-08 34.7 0.0 5.0 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 GAK67914.1 - 1.8e-10 40.6 0.0 1.5e-09 37.6 0.0 2.6 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 GAK67914.1 - 0.016 15.4 4.9 5.4 7.4 0.1 5.5 6 2 0 6 6 6 0 DNA ligase 3 BRCT domain RRM_1 PF00076.22 GAK67915.1 - 1.5e-13 50.3 0.0 2.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GAK67915.1 - 9.4e-08 32.5 23.9 2.5e-07 31.2 10.8 2.5 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 GAK67915.1 - 0.00044 20.1 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RSN1_7TM PF02714.15 GAK67916.1 - 1.9e-74 250.4 30.1 3.2e-74 249.7 29.9 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAK67916.1 - 1.6e-37 128.6 0.3 1.6e-37 128.6 0.3 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAK67916.1 - 1.4e-33 116.6 0.0 2.3e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF4024 PF13216.6 GAK67916.1 - 0.082 12.9 0.2 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) Beach PF02138.18 GAK67917.1 - 1.3e-114 382.3 0.0 2.1e-114 381.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAK67917.1 - 1.5e-08 34.6 0.0 4.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 GAK67917.1 - 2.9e-07 31.1 4.4 0.029 15.3 0.6 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat FYVE PF01363.21 GAK67917.1 - 8.3e-07 29.1 9.0 1.6e-06 28.2 9.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF4704 PF15787.5 GAK67917.1 - 1.4e-06 27.8 0.4 1.4e-05 24.5 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 GAK67917.1 - 0.029 13.6 2.7 0.022 14.0 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Siva PF05458.12 GAK67917.1 - 1.3 8.7 5.7 3.1 7.4 5.7 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) IBR PF01485.21 GAK67917.1 - 9 6.6 8.5 0.78 10.0 3.2 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain HSP20 PF00011.21 GAK67918.1 - 3.8e-17 62.3 0.3 3.8e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAK67918.1 - 7.7e-06 25.4 0.1 3.5e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 GAK67918.1 - 0.014 15.5 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 GvpH DUF1556 PF07590.11 GAK67918.1 - 0.16 12.3 1.8 0.37 11.1 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) PI-PLC-C1 PF16670.5 GAK67919.1 - 0.00057 19.1 0.4 0.28 10.2 0.0 3.1 2 1 1 3 3 3 2 Phosphoinositide phospholipase C, Ca2+-dependent UL2 PF08196.11 GAK67919.1 - 0.051 13.5 0.1 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 UL2 protein PI-PLC-X PF00388.19 GAK67919.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Oest_recep PF02159.15 GAK67919.1 - 2.2 8.8 6.0 0.23 12.0 0.7 2.1 3 0 0 3 3 3 0 Oestrogen receptor PH PF00169.29 GAK67920.1 - 9.6e-07 29.3 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAK67920.1 - 0.013 15.9 0.1 0.031 14.7 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain SDA1 PF05285.12 GAK67920.1 - 0.38 10.1 13.3 0.03 13.8 6.6 2.2 2 0 0 2 2 2 0 SDA1 ERCC3_RAD25_C PF16203.5 GAK67921.1 - 2.5e-124 413.4 0.2 4.9e-124 412.4 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 GAK67921.1 - 1.2e-37 128.9 0.0 2.4e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAK67921.1 - 2.1e-17 63.7 0.0 3.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAK67921.1 - 6.9e-10 39.3 0.1 1.9e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GAK67921.1 - 1.1e-08 34.2 0.0 1.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 GAK67921.1 - 9e-06 25.6 0.6 3.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SPT6_acidic PF14632.6 GAK67921.1 - 3.6 8.2 7.5 4.9 7.8 1.8 3.1 2 1 0 2 2 2 0 Acidic N-terminal SPT6 Ras PF00071.22 GAK67922.1 - 8.8e-49 165.2 0.0 1e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK67922.1 - 5.3e-21 75.1 0.0 7.3e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK67922.1 - 5.9e-08 32.4 0.0 7.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CPT PF07931.12 GAK67922.1 - 0.0018 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Gtr1_RagA PF04670.12 GAK67922.1 - 0.0035 16.7 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAK67922.1 - 0.0083 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAK67922.1 - 0.021 14.4 0.0 0.079 12.5 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAK67922.1 - 0.023 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAK67922.1 - 0.086 13.2 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain UQ_con PF00179.26 GAK67923.1 - 2.3e-18 66.2 0.0 3.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_3 PF07859.13 GAK67924.1 - 2.1e-23 83.3 0.0 4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAK67924.1 - 5.1e-05 22.3 0.0 7.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF1168 PF06658.12 GAK67925.1 - 3.5e-38 130.5 15.5 5.1e-38 130.0 15.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Vps16_C PF04840.12 GAK67926.1 - 9.6e-74 248.3 4.0 6.9e-49 166.6 2.8 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 GAK67926.1 - 1.5e-69 234.7 0.0 2.6e-43 148.3 0.0 3.3 3 0 0 3 3 3 3 Vps16, N-terminal region WLM PF08325.10 GAK67927.1 - 3.1e-30 105.7 4.4 3.1e-30 105.7 4.4 2.7 2 1 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 GAK67927.1 - 7.4e-06 25.2 3.5 1.3e-05 24.4 3.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 GAK67927.1 - 0.0059 16.7 0.2 0.021 14.9 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF2509 PF10713.9 GAK67927.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) GATA PF00320.27 GAK67929.1 - 4.6e-12 45.3 2.7 8.3e-12 44.5 2.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Sugar_tr PF00083.24 GAK67930.1 - 2.7e-87 293.5 18.5 3.5e-87 293.1 18.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK67930.1 - 5.2e-20 71.7 19.7 5.2e-20 71.7 19.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily GST_N PF02798.20 GAK67931.1 - 6e-16 58.6 0.0 1.5e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAK67931.1 - 2.4e-12 47.1 0.0 4.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAK67931.1 - 2.3e-11 43.8 0.0 4.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L5_C PF00673.21 GAK67932.1 - 6.5e-22 77.5 0.1 2.4e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAK67932.1 - 1.8e-16 60.2 0.0 3.6e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 PDZ_5 PF17817.1 GAK67933.1 - 0.027 14.8 0.1 0.075 13.3 0.1 1.7 1 0 0 1 1 1 0 PDZ domain PI3_PI4_kinase PF00454.27 GAK67934.1 - 1.2e-53 182.5 0.0 2.2e-53 181.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 GAK67934.1 - 2.4e-38 131.6 0.3 8.9e-38 129.8 0.3 2.1 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 GAK67934.1 - 6.9e-09 35.4 0.1 1.7e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain PDH PF02153.17 GAK67935.1 - 4.9e-17 61.8 0.0 1.1e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 Prephenate dehydrogenase F420_oxidored PF03807.17 GAK67935.1 - 1.1e-05 26.0 0.1 0.00017 22.1 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAK67935.1 - 1.7e-05 25.1 0.0 4.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 GAK67935.1 - 0.00061 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 GAK67935.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 GAK67935.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 GAK67935.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNRNP27 PF08648.12 GAK67936.1 - 1e-29 102.3 0.5 1.9e-29 101.5 0.5 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins NDUF_B4 PF07225.12 GAK67937.1 - 0.00024 21.0 0.1 0.00028 20.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Integrase_Zn PF02022.19 GAK67937.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Integrase Zinc binding domain PX PF00787.24 GAK67938.1 - 4.6e-08 33.0 0.2 1e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 PX domain Melibiase_2 PF16499.5 GAK67939.1 - 3.3e-57 193.8 6.2 2.1e-56 191.2 6.2 2.0 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAK67939.1 - 1e-09 38.3 0.7 4e-09 36.4 0.7 2.0 1 1 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAK67939.1 - 8.6e-07 28.2 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 GAK67939.1 - 8.3e-05 20.6 0.0 0.00013 19.9 0.0 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase_2_C PF17450.2 GAK67939.1 - 0.0008 19.6 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain CFEM PF05730.11 GAK67940.1 - 0.00049 20.1 10.0 0.00092 19.3 10.0 1.4 1 0 0 1 1 1 1 CFEM domain TIL PF01826.17 GAK67940.1 - 6.3 7.1 7.9 12 6.3 7.9 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain SNF2_N PF00176.23 GAK67942.1 - 4.4e-07 28.9 0.0 7.4e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 GAK67942.1 - 0.0021 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4407 PF14362.6 GAK67942.1 - 0.66 9.3 6.0 1.2 8.4 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HMA PF00403.26 GAK67943.1 - 4e-12 46.4 0.6 2.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 Heavy-metal-associated domain GnsAB_toxin PF08178.11 GAK67943.1 - 0.047 13.6 0.7 3.4 7.7 0.4 2.2 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system HA2 PF04408.23 GAK67944.1 - 1.6e-20 73.4 0.0 1.6e-20 73.4 0.0 3.2 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAK67944.1 - 6.8e-15 55.2 0.0 2.2e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAK67944.1 - 1.9e-13 50.7 0.0 4.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAK67944.1 - 1.3e-08 34.8 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK67944.1 - 5.6e-06 26.7 0.4 2.6e-05 24.5 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAK67944.1 - 0.00057 19.7 0.0 0.00057 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 GAK67944.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 GAK67944.1 - 0.002 18.5 0.1 0.0051 17.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAK67944.1 - 0.0026 17.9 0.2 0.055 13.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAK67944.1 - 0.0035 16.5 0.0 0.008 15.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 GAK67944.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 GAK67944.1 - 0.022 14.4 0.2 0.054 13.1 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 GAK67944.1 - 0.029 14.9 0.4 0.077 13.5 0.0 2.0 2 0 0 2 2 1 0 ABC transporter ATPase PF06745.13 GAK67944.1 - 0.038 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 GAK67944.1 - 0.042 13.9 0.1 0.32 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAK67944.1 - 0.072 13.5 0.0 0.45 10.9 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 GAK67944.1 - 0.16 11.6 0.0 0.79 9.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 GAK67944.1 - 0.19 11.3 0.1 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain p450 PF00067.22 GAK67945.1 - 1.1e-59 202.4 0.0 2.8e-52 178.0 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Perilipin PF03036.16 GAK67946.1 - 1.6e-11 43.9 2.0 6.1e-08 32.1 0.1 2.3 1 1 1 2 2 2 2 Perilipin family FTA4 PF13093.6 GAK67946.1 - 0.038 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 LIF_OSM PF01291.17 GAK67946.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 LIF / OSM family AAA PF00004.29 GAK67947.1 - 7.3e-57 191.5 0.0 3e-43 147.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 GAK67947.1 - 8.6e-25 87.0 0.1 2e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 GAK67947.1 - 2.5e-16 59.2 0.5 4.4e-11 42.4 0.1 2.9 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAK67947.1 - 7.9e-10 39.4 13.5 2e-05 25.1 1.0 4.9 4 2 1 5 5 3 2 AAA ATPase domain AAA_25 PF13481.6 GAK67947.1 - 2.6e-07 30.4 4.6 0.051 13.2 0.0 4.3 2 2 1 4 4 4 3 AAA domain AAA_22 PF13401.6 GAK67947.1 - 4.1e-07 30.3 4.6 0.037 14.3 0.0 4.7 4 2 2 6 6 4 2 AAA domain TsaE PF02367.17 GAK67947.1 - 1e-06 28.7 0.0 0.042 13.8 0.0 3.0 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 GAK67947.1 - 1.6e-06 28.0 0.0 0.0033 17.2 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAK67947.1 - 1.9e-06 28.1 0.0 0.048 13.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 GAK67947.1 - 6.1e-06 26.8 0.0 0.13 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAK67947.1 - 1.5e-05 24.5 0.5 0.12 11.7 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 GAK67947.1 - 2.2e-05 23.9 0.0 0.0066 15.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 GAK67947.1 - 2.7e-05 24.2 0.2 0.43 10.6 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAK67947.1 - 4.6e-05 23.7 0.1 0.077 13.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 GAK67947.1 - 6.3e-05 22.3 0.1 0.068 12.4 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin AAA_17 PF13207.6 GAK67947.1 - 6.9e-05 23.3 0.2 0.37 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAK67947.1 - 7.3e-05 23.1 0.0 0.65 10.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 GAK67947.1 - 0.00013 22.0 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 GAK67947.1 - 0.00018 20.9 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 GAK67947.1 - 0.00066 19.5 0.0 1.8 8.3 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 GAK67947.1 - 0.00087 19.4 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 GAK67947.1 - 0.0013 18.6 2.1 0.89 9.5 0.3 3.5 3 1 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 GAK67947.1 - 0.0015 18.4 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 GAK67947.1 - 0.0017 18.5 0.0 0.051 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 GAK67947.1 - 0.0025 17.7 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 GAK67947.1 - 0.0029 17.4 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 GAK67947.1 - 0.0031 16.8 0.0 2.4 7.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain SKI PF01202.22 GAK67947.1 - 0.0047 17.1 0.0 5 7.2 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 GAK67947.1 - 0.0064 16.8 0.0 0.23 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GAK67947.1 - 0.0066 16.6 0.1 0.92 9.6 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_24 PF13479.6 GAK67947.1 - 0.0077 16.0 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 GAK67947.1 - 0.008 15.6 0.1 2.3 7.5 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 GAK67947.1 - 0.01 15.3 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAK67947.1 - 0.021 14.8 0.0 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 GAK67947.1 - 0.025 14.5 1.9 0.49 10.3 0.0 3.4 3 1 1 4 4 4 0 Adenylylsulphate kinase ABC_tran PF00005.27 GAK67947.1 - 0.054 14.0 0.2 21 5.6 0.1 3.2 2 1 0 3 3 3 0 ABC transporter PhoH PF02562.16 GAK67947.1 - 0.077 12.4 0.2 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein KTI12 PF08433.10 GAK67947.1 - 0.13 11.7 0.1 1 8.8 0.0 2.3 2 1 0 2 2 2 0 Chromatin associated protein KTI12 eRF1_2 PF03464.15 GAK67948.1 - 7.8e-46 155.7 0.0 1.9e-45 154.5 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAK67948.1 - 2e-37 128.1 0.1 3.9e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GAK67948.1 - 2.9e-19 69.3 0.0 5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 GAK67948.1 - 8.2e-08 32.6 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 GAK67948.1 - 6.1e-06 26.5 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF3440 PF11922.8 GAK67948.1 - 0.022 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) SAP130_C PF16014.5 GAK67948.1 - 2.7 7.0 8.8 3.9 6.5 8.8 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DEAD_2 PF06733.15 GAK67949.1 - 4.1e-51 173.1 0.0 4.4e-45 153.4 0.0 2.6 3 0 0 3 3 3 2 DEAD_2 HBB PF06777.11 GAK67949.1 - 1.2e-46 158.8 1.1 3.4e-43 147.5 0.2 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 GAK67949.1 - 3.6e-44 150.9 0.0 7.8e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 GAK67949.1 - 0.00015 21.8 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAK67949.1 - 0.0036 17.1 0.4 1.3 8.7 0.0 2.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase DUF4604 PF15377.6 GAK67951.1 - 3.8e-23 82.8 13.8 4.7e-23 82.5 13.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) EHN PF06441.12 GAK67952.1 - 2.4e-24 85.8 1.2 6e-24 84.5 0.0 2.3 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAK67952.1 - 2.2e-14 53.7 0.3 4.7e-14 52.6 0.3 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold NUC173 PF08161.12 GAK67953.1 - 6.3e-62 208.9 0.2 1.2e-60 204.7 0.0 2.8 2 0 0 2 2 2 1 NUC173 domain MMS19_C PF12460.8 GAK67953.1 - 1.6e-05 24.2 9.3 0.0083 15.3 0.4 2.7 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal DUF1018 PF06252.12 GAK67953.1 - 0.12 13.4 1.4 6.2 7.8 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1018) dsDNA_bind PF01984.20 GAK67953.1 - 0.53 10.6 5.3 0.49 10.7 0.5 3.1 2 0 0 2 2 2 0 Double-stranded DNA-binding domain THOC2_N PF16134.5 GAK67953.1 - 1.1 7.7 5.8 0.47 9.0 2.9 1.7 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus CDC45 PF02724.14 GAK67953.1 - 6 5.0 7.7 13 3.9 7.7 1.6 1 0 0 1 1 1 0 CDC45-like protein HMGL-like PF00682.19 GAK67954.1 - 5.6e-73 245.7 0.0 1e-72 244.9 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Rib_5-P_isom_A PF06026.14 GAK67954.1 - 6e-59 198.5 0.0 1.3e-58 197.4 0.0 1.6 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) LeuA_dimer PF08502.10 GAK67954.1 - 7.8e-20 71.1 0.9 7.1e-09 35.7 0.1 3.0 1 1 1 2 2 2 2 LeuA allosteric (dimerisation) domain Spo7 PF03907.13 GAK67955.1 - 4.3e-44 150.6 1.7 4.3e-44 150.6 1.7 1.6 1 1 1 2 2 2 1 Spo7-like protein Tmemb_18A PF09771.9 GAK67955.1 - 7.3e-05 23.1 3.8 0.00019 21.8 0.6 2.1 2 0 0 2 2 2 1 Transmembrane protein 188 CCDC24 PF15669.5 GAK67955.1 - 0.012 15.5 3.8 4.5 7.1 4.1 2.2 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family NEMP PF10225.9 GAK67955.1 - 0.013 15.2 0.8 0.02 14.6 0.8 1.2 1 0 0 1 1 1 0 NEMP family Wzy_C PF04932.15 GAK67955.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 1 0 1 1 1 0 O-Antigen ligase Sec10 PF07393.11 GAK67956.1 - 3.3e-82 277.1 0.0 7.6e-82 275.9 0.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec10 Mito_carr PF00153.27 GAK67956.1 - 1.6e-55 185.0 7.1 4.6e-23 81.0 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 GAK67956.1 - 0.00011 22.1 0.2 0.00027 20.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAK67956.1 - 0.013 15.3 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 F-box domain SET PF00856.28 GAK67957.1 - 2.3e-07 31.3 0.0 8.8e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF1365 PF07103.11 GAK67958.1 - 6.4e-63 212.6 0.0 1.1e-62 211.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Rep_fac-A_3 PF08661.11 GAK67959.1 - 2.4e-23 82.5 0.2 2.6e-23 82.3 0.2 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 She9_MDM33 PF05546.11 GAK67960.1 - 3.5e-65 219.5 9.3 5.2e-65 219.0 9.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF2371 PF10177.9 GAK67960.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) ATP-synt_D PF01813.17 GAK67961.1 - 3.9e-73 245.5 1.9 5e-73 245.1 1.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D XRN_M PF17846.1 GAK67961.1 - 0.94 8.4 5.3 1.6 7.6 5.3 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 GAK67961.1 - 2.4 6.2 4.0 3 5.9 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RhlB PF12300.8 GAK67961.1 - 3.3 7.8 10.8 0.66 10.1 4.8 2.3 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB TMEM119 PF15724.5 GAK67961.1 - 6.4 6.8 10.0 12 5.9 10.0 1.3 1 0 0 1 1 1 0 TMEM119 family GDC-P PF02347.16 GAK67962.1 - 1.4e-182 607.4 0.0 2.8e-170 566.8 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 GAK67962.1 - 1.5e-06 27.8 0.1 2.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TRM PF02005.16 GAK67963.1 - 8.9e-37 127.1 0.4 5.9e-26 91.5 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Amino_oxidase PF01593.24 GAK67964.1 - 1.5e-23 83.8 0.0 6.9e-23 81.6 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK67964.1 - 3.8e-12 46.2 0.4 1.3e-11 44.5 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAK67964.1 - 8.4e-11 41.6 0.3 3.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK67964.1 - 1.5e-09 37.9 1.4 1.3e-08 34.8 1.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK67964.1 - 9.3e-06 25.0 1.2 0.00041 19.6 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAK67964.1 - 1.7e-05 23.7 0.3 0.0004 19.2 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAK67964.1 - 0.001 18.5 0.1 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 GAK67964.1 - 0.0012 17.8 0.1 0.15 10.8 0.0 2.1 2 0 0 2 2 2 1 MCRA family Pyr_redox PF00070.27 GAK67964.1 - 0.0023 18.4 8.1 0.079 13.5 0.4 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAK67964.1 - 0.0029 17.3 0.5 0.0059 16.3 0.5 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 GAK67964.1 - 0.0047 16.2 1.3 0.0054 16.0 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 GAK67964.1 - 0.0066 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 GAK67964.1 - 0.017 14.4 0.2 0.029 13.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAK67964.1 - 0.024 13.5 3.5 0.98 8.2 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 GAK67964.1 - 0.024 14.6 3.0 0.062 13.3 0.5 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 GAK67964.1 - 0.063 13.9 0.3 0.18 12.4 0.3 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 GAK67964.1 - 0.065 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.9 GAK67964.1 - 0.082 12.8 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Rossmann-like domain GMC_oxred_N PF00732.19 GAK67964.1 - 0.088 12.2 0.2 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_7 PF13241.6 GAK67964.1 - 0.099 13.1 0.3 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 GAK67964.1 - 0.11 11.7 0.2 0.2 10.8 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 GAK67964.1 - 0.16 11.0 3.0 0.11 11.6 0.4 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Arteri_nsp7a PF16749.5 GAK67964.1 - 0.18 12.0 0.4 4.5 7.5 0.0 2.5 3 0 0 3 3 2 0 Arterivirus nonstructural protein 7 alpha GIDA PF01134.22 GAK67964.1 - 0.99 8.4 4.1 0.38 9.8 0.8 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Zn_clus PF00172.18 GAK67965.1 - 5.4e-07 29.6 11.2 1e-06 28.7 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK67965.1 - 2.9e-06 26.5 0.1 5.8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.22 GAK67967.1 - 4.6e-10 39.7 0.0 7.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Velvet PF11754.8 GAK67972.1 - 1.2e-36 126.9 0.0 1.5e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.8 GAK67973.1 - 1.6e-55 188.7 0.0 3.2e-38 132.1 0.0 3.4 2 2 1 3 3 3 2 Velvet factor UCH PF00443.29 GAK67975.1 - 1.6e-71 240.8 0.0 3.2e-71 239.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAK67975.1 - 1.4e-17 64.1 0.0 3.2e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 GAK67975.1 - 2.7e-11 43.6 0.0 4.4e-05 23.2 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 GAK67975.1 - 0.0022 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.23 GAK67975.1 - 0.15 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family BCS1_N PF08740.11 GAK67976.1 - 4e-57 193.2 0.0 6.2e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAK67976.1 - 5.5e-17 62.4 0.0 9.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAK67976.1 - 0.0036 16.9 0.0 0.074 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAK67976.1 - 0.0081 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAK67976.1 - 0.019 15.4 0.2 0.019 15.4 0.2 3.3 2 1 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 GAK67976.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAK67976.1 - 0.033 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 GAK67976.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase zn-ribbon_14 PF16503.5 GAK67977.1 - 7.7e-17 60.5 2.0 7.7e-17 60.5 2.0 3.2 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 GAK67977.1 - 1.3e-15 57.6 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 PP-loop family CTU2 PF10288.9 GAK67977.1 - 0.0026 18.0 0.8 0.018 15.3 0.1 2.5 3 0 0 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 DUF2616 PF11077.8 GAK67977.1 - 0.084 12.6 2.1 0.95 9.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) WD40 PF00400.32 GAK67978.1 - 1.4e-08 35.2 8.9 0.0021 18.8 0.4 5.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK67978.1 - 0.092 13.1 0.0 14 6.0 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4746 PF15928.5 GAK67978.1 - 0.72 9.2 0.0 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Zn_clus PF00172.18 GAK67979.1 - 1.6e-05 25.0 7.8 2.9e-05 24.1 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 GAK67980.1 - 9.8e-129 429.8 1.6 1.2e-128 429.5 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HORMA PF02301.18 GAK67981.1 - 1.5e-24 86.8 0.0 1.8e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Potex_coat PF06184.11 GAK67981.1 - 0.0097 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Potexvirus coat protein ATG101 PF07855.12 GAK67981.1 - 0.018 15.0 0.1 0.048 13.6 0.1 1.7 1 1 0 1 1 1 0 Autophagy-related protein 101 bacHORMA_2 PF18173.1 GAK67981.1 - 0.082 12.8 0.2 0.29 11.0 0.2 1.9 1 1 1 2 2 2 0 Bacterial HORMA domain 2 zf-RING_2 PF13639.6 GAK67982.1 - 1.2e-09 38.3 1.5 1.2e-09 38.3 1.5 3.2 3 0 0 3 3 3 1 Ring finger domain zinc_ribbon_9 PF14369.6 GAK67982.1 - 1.5e-09 38.0 0.7 1.5e-09 38.0 0.7 2.9 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_3 PF13920.6 GAK67982.1 - 6.5e-07 29.1 9.6 0.00039 20.2 0.8 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAK67982.1 - 9.9e-07 28.5 2.7 9.9e-07 28.5 2.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAK67982.1 - 5.5e-06 26.6 8.0 5.5e-06 26.6 8.0 2.6 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAK67982.1 - 7.1e-05 22.5 0.3 0.0002 21.0 0.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 GAK67982.1 - 0.00014 21.6 1.3 0.00014 21.6 1.3 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAK67982.1 - 0.00048 19.9 0.7 0.00048 19.9 0.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAK67982.1 - 0.0019 18.2 3.2 0.0019 18.2 3.2 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAK67982.1 - 0.0019 18.2 4.4 0.0019 18.2 4.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAK67982.1 - 0.0059 16.5 15.3 0.013 15.5 6.0 3.2 2 1 1 3 3 3 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAK67982.1 - 0.0093 15.6 1.4 0.0093 15.6 1.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type HypA PF01155.19 GAK67982.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.3 2 1 1 3 3 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_4 PF14570.6 GAK67982.1 - 0.59 10.0 10.4 6.6 6.6 0.2 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 GAK67982.1 - 0.61 10.2 12.6 0.13 12.4 1.3 3.1 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 GAK67982.1 - 0.83 9.7 8.5 0.33 11.0 0.4 2.6 2 1 1 3 3 3 0 Double zinc ribbon zf-TFIIB PF13453.6 GAK67982.1 - 0.97 8.8 6.4 12 5.4 0.1 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger His_Phos_1 PF00300.22 GAK67983.1 - 1.1e-17 64.4 2.3 6.7e-13 48.8 0.3 3.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) GMP_synt_C PF00958.22 GAK67984.1 - 2.6e-43 146.0 0.0 5e-43 145.1 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 GAK67984.1 - 2.6e-37 128.5 0.0 6.9e-37 127.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 GAK67984.1 - 1e-11 44.4 0.2 2.6e-07 30.0 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 GAK67984.1 - 1.2e-09 38.3 0.1 2.3e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 GAK67984.1 - 5.8e-05 22.0 0.2 0.00011 21.1 0.2 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 GAK67984.1 - 0.0001 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 GAK67984.1 - 0.0013 18.1 0.2 0.0021 17.4 0.2 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 GAK67984.1 - 0.0017 17.9 0.1 0.01 15.4 0.1 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 GAK67984.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family sCache_like PF16736.5 GAK67984.1 - 0.067 13.3 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Single Cache-like ATP_bind_3 PF01171.20 GAK67984.1 - 0.16 11.7 0.3 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 PP-loop family IF3_N PF05198.16 GAK67985.1 - 0.0015 18.8 0.0 0.0087 16.3 0.0 2.1 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 GAK67985.1 - 0.0015 18.2 0.0 0.004 16.8 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_C PF00707.22 GAK67985.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Ribosomal_S22 PF08136.11 GAK67985.1 - 0.15 12.5 0.4 0.8 10.1 0.2 2.0 1 1 1 2 2 2 0 30S ribosomal protein subunit S22 family WD40 PF00400.32 GAK67986.1 - 3.1e-13 49.9 2.3 0.0013 19.5 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK67986.1 - 1.5e-08 34.8 0.0 0.024 14.9 0.0 4.2 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cys_Met_Meta_PP PF01053.20 GAK67987.1 - 5.9e-18 64.5 0.0 1.6e-17 63.2 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme GYF PF02213.16 GAK67987.1 - 0.14 11.8 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 GYF domain CTD_bind PF04818.13 GAK67988.1 - 0.0029 18.4 0.0 0.0077 17.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. FliX PF10768.9 GAK67988.1 - 0.05 14.1 3.7 0.17 12.4 3.7 1.9 1 0 0 1 1 1 0 Class II flagellar assembly regulator CFIA_Pcf11 PF11526.8 GAK67988.1 - 3.2 8.3 6.6 0.73 10.4 0.2 3.0 3 1 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 ParA PF10609.9 GAK67989.1 - 7.4e-85 284.3 0.0 1.6e-84 283.2 0.0 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAK67989.1 - 1.4e-06 28.4 0.0 9.1e-05 22.5 0.1 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 GAK67989.1 - 6.4e-05 22.3 0.1 0.0023 17.2 0.6 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 GAK67989.1 - 0.037 14.0 0.4 0.42 10.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain PcrB PF01884.17 GAK67989.1 - 0.039 13.4 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 PcrB family RsgA_GTPase PF03193.16 GAK67989.1 - 0.042 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 GAK67989.1 - 0.09 12.6 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAK67989.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAK67989.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.11 GAK67989.1 - 0.26 11.0 0.1 0.39 10.4 0.1 1.2 1 0 0 1 1 1 0 Virulence-associated protein E ABC2_membrane PF01061.24 GAK67990.1 - 2.7e-76 255.6 66.3 2.4e-40 138.2 25.5 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAK67990.1 - 4.4e-36 124.4 0.0 3.1e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAK67990.1 - 7.7e-33 112.3 5.5 7.5e-31 105.9 0.4 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAK67990.1 - 3.5e-12 46.8 0.4 8e-11 42.4 0.0 2.7 2 0 0 2 2 2 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 GAK67990.1 - 8.9e-06 25.7 0.1 3.2e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAK67990.1 - 2.4e-05 24.8 0.0 0.0023 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 GAK67990.1 - 0.00017 20.9 45.3 0.01 15.0 15.9 3.7 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 GAK67990.1 - 0.00034 20.2 0.0 0.0039 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAK67990.1 - 0.0022 17.9 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAK67990.1 - 0.0035 17.6 0.1 0.056 13.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 GAK67990.1 - 0.0077 16.2 0.1 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain dNK PF01712.19 GAK67990.1 - 0.015 15.2 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_29 PF13555.6 GAK67990.1 - 0.016 14.9 0.2 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 GAK67990.1 - 0.05 13.3 0.1 0.69 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 GAK67990.1 - 0.051 13.0 0.0 2.3 7.6 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 GAK67990.1 - 0.06 13.4 0.1 0.51 10.4 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 GAK67990.1 - 0.082 13.3 0.1 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GAK67990.1 - 0.09 13.3 0.8 0.28 11.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 GAK67990.1 - 0.13 12.3 0.2 0.9 9.6 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 GAK67990.1 - 0.21 11.1 0.7 0.92 9.1 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NAD_binding_4 PF07993.12 GAK67991.1 - 3e-14 52.8 0.0 6.1e-12 45.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 GAK67991.1 - 1e-10 41.1 0.0 2.7e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAK67991.1 - 1.2e-09 38.0 0.3 5.2e-09 35.9 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAK67991.1 - 0.00032 20.2 0.6 0.00057 19.4 0.1 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAK67991.1 - 0.019 14.9 0.5 0.57 10.1 0.4 2.7 2 1 0 2 2 2 0 KR domain NmrA PF05368.13 GAK67991.1 - 0.048 13.2 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 2_5_RNA_ligase2 PF13563.6 GAK67992.1 - 5.5e-21 75.1 1.1 8.2e-21 74.5 1.1 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 GAK67992.1 - 0.0033 17.6 0.2 0.49 10.6 0.2 2.7 1 1 0 1 1 1 1 LigT like Phosphoesterase 2-Hacid_dh_C PF02826.19 GAK67993.1 - 2.4e-39 134.5 0.0 3.4e-38 130.8 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAK67993.1 - 1.3e-25 89.6 0.0 6.6e-25 87.3 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 GAK67993.1 - 3.7e-05 24.2 0.0 9.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Mito_carr PF00153.27 GAK67994.1 - 1.5e-51 172.2 7.4 2.2e-18 65.9 0.2 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein NdhS PF11623.8 GAK67994.1 - 0.16 11.7 0.1 11 5.8 0.0 2.6 1 1 1 2 2 2 0 NAD(P)H dehydrogenase subunit S DUF389 PF04087.14 GAK67994.1 - 3.1 7.8 6.2 0.17 11.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Zip PF02535.22 GAK67995.1 - 1.1e-37 130.1 24.2 1.1e-37 130.1 24.2 3.0 2 1 0 2 2 2 1 ZIP Zinc transporter HCV_NS4a PF01006.20 GAK67995.1 - 1.4 8.8 4.7 5.9 6.7 4.7 2.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF4514 PF14986.6 GAK67995.1 - 1.6 8.7 8.4 0.064 13.2 1.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) ADC PF06314.11 GAK67996.1 - 2.2e-17 63.4 0.1 3.6e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Cupin_2 PF07883.11 GAK67997.1 - 4.2e-05 23.2 0.0 7.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Peroxidase_2 PF01328.17 GAK67998.1 - 5.6e-52 177.0 0.0 7.4e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 BTAD PF03704.17 GAK67999.1 - 0.025 15.0 3.0 0.15 12.5 1.1 3.3 2 1 0 2 2 2 0 Bacterial transcriptional activator domain GGDEF_2 PF17853.1 GAK67999.1 - 0.27 11.5 3.1 3.9 7.8 0.1 4.2 3 0 0 3 3 3 0 GGDEF-like domain HEAT_2 PF13646.6 GAK67999.1 - 0.53 10.7 22.3 0.063 13.7 0.7 5.0 6 0 0 6 6 6 0 HEAT repeats TPR_19 PF14559.6 GAK67999.1 - 0.53 10.8 5.2 0.65 10.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat FoP_duplication PF13865.6 GAK68000.1 - 0.56 10.8 5.1 0.96 10.0 5.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SPX PF03105.19 GAK68000.1 - 3.1 7.6 11.1 3.2 7.6 11.1 1.1 1 0 0 1 1 1 0 SPX domain MFS_1 PF07690.16 GAK68002.1 - 2.8e-36 125.2 52.7 2.1e-35 122.3 51.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAK68002.1 - 2e-11 43.4 14.4 2e-11 43.4 14.4 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAK68002.1 - 9.2e-07 27.7 22.0 1.2e-06 27.2 22.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AATase PF07247.12 GAK68003.1 - 0.064 11.8 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Con-6 PF10346.9 GAK68004.1 - 0.036 14.1 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Conidiation protein 6 UDPGT PF00201.18 GAK68006.1 - 0.061 12.1 0.0 0.16 10.7 0.1 1.6 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 GAK68006.1 - 0.088 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_4 PF13692.6 GAK68006.1 - 0.13 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 FA_hydroxylase PF04116.13 GAK68007.1 - 3e-22 79.4 4.5 3e-22 79.4 4.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RED_N PF07808.13 GAK68009.1 - 0.01 15.5 0.3 0.016 14.8 0.3 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2058 PF09831.9 GAK68010.1 - 0.087 13.0 4.1 0.15 12.2 4.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) SKN1 PF03935.15 GAK68011.1 - 2.1e-189 630.1 2.0 3e-189 629.6 2.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 GAK68011.1 - 0.0002 20.9 1.3 0.29 10.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 4HBT PF03061.22 GAK68012.1 - 2.8e-06 27.6 0.1 0.039 14.3 0.0 2.7 3 0 0 3 3 3 2 Thioesterase superfamily GILT PF03227.16 GAK68013.1 - 4.9e-14 52.5 0.3 9.4e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) zf-RING_2 PF13639.6 GAK68015.1 - 3.3e-07 30.5 16.1 2.9e-06 27.5 3.1 3.6 3 1 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.7 GAK68015.1 - 0.00016 21.9 12.7 0.0014 18.8 3.0 3.2 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAK68015.1 - 0.0042 16.9 11.4 0.075 12.9 0.8 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAK68015.1 - 0.0053 16.8 5.9 0.0054 16.8 0.5 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAK68015.1 - 0.015 15.3 9.1 0.039 14.0 1.4 2.9 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAK68015.1 - 0.024 14.5 0.8 0.024 14.5 0.8 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK68015.1 - 0.024 14.6 10.0 0.05 13.6 0.4 3.2 3 0 0 3 3 3 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GAK68015.1 - 0.16 11.8 12.1 0.79 9.6 1.7 3.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAK68015.1 - 0.18 11.6 5.1 6.9 6.5 0.1 3.3 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAK68015.1 - 1.5 8.7 19.5 0.24 11.3 1.8 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAK68015.1 - 4.3 7.5 9.1 0.39 10.9 2.7 2.4 2 0 0 2 2 2 0 RING-variant domain Aa_trans PF01490.18 GAK68016.1 - 3.1e-05 22.9 6.2 0.00097 17.9 5.7 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF3533 PF12051.8 GAK68017.1 - 3.6e-100 335.5 14.5 4.2e-100 335.3 14.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) CrgA PF06781.12 GAK68017.1 - 2.3 8.3 5.9 32 4.7 1.3 3.4 3 1 0 3 3 3 0 Cell division protein CrgA Aldolase_II PF00596.21 GAK68018.1 - 1.3e-24 87.1 0.0 1.8e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase_4 PF12146.8 GAK68019.1 - 2.6e-08 33.5 0.1 1.2e-07 31.2 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAK68019.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK68019.1 - 2.1e-05 25.2 0.5 3.7e-05 24.4 0.1 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAK68019.1 - 0.00066 19.6 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 GAK68019.1 - 0.052 13.3 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ribonuc_red_sm PF00268.21 GAK68020.1 - 4.7e-121 403.5 0.7 5.9e-121 403.2 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain 3Beta_HSD PF01073.19 GAK68021.1 - 1.2e-15 57.2 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAK68021.1 - 2.9e-14 53.1 0.0 7e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAK68021.1 - 1e-12 47.8 0.0 1.3e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAK68021.1 - 1.1e-10 41.8 0.0 1.9e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAK68021.1 - 2.3e-08 33.8 0.0 4.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAK68021.1 - 2e-06 27.5 0.1 2.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 GAK68021.1 - 0.00032 20.2 0.1 0.002 17.6 0.0 2.0 2 1 1 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAK68021.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAK68021.1 - 0.01 15.8 0.1 0.049 13.5 0.1 1.9 1 1 0 1 1 1 0 KR domain Ldh_1_N PF00056.23 GAK68021.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AnmK PF03702.14 GAK68024.1 - 3.2e-88 296.3 0.0 3.8e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Methyltransf_2 PF00891.18 GAK68024.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain BcrAD_BadFG PF01869.20 GAK68024.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Carbam_trans_N PF02543.15 GAK68024.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus KORA PF16509.5 GAK68024.1 - 0.2 12.0 0.1 3.9 7.8 0.0 2.3 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Sugar_tr PF00083.24 GAK68025.1 - 4.7e-91 305.9 22.2 5.8e-91 305.6 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK68025.1 - 2.7e-31 108.8 46.5 1e-24 87.2 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAK68025.1 - 0.011 14.0 3.7 0.021 13.2 2.2 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAK68026.1 - 1.9e-15 56.6 0.0 2.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK68026.1 - 0.00021 21.4 8.9 0.00039 20.5 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb2_6 PF00562.28 GAK68027.1 - 3.1e-125 418.3 0.3 3.6e-125 418.1 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 GAK68027.1 - 1.3e-30 105.7 0.1 2.2e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 GAK68027.1 - 3.2e-10 40.4 1.6 5e-10 39.8 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.7 GAK68027.1 - 0.1 12.6 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Acetyltransf_1 PF00583.25 GAK68030.1 - 8.9e-08 32.4 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAK68030.1 - 8.7e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAK68030.1 - 1.9e-06 27.8 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK68030.1 - 0.0001 22.7 0.1 0.00019 21.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAK68030.1 - 0.0026 17.9 0.2 0.0042 17.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Prenyltrans PF00432.21 GAK68031.1 - 4.3e-50 167.1 7.5 7.3e-11 41.6 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAK68031.1 - 6.5e-05 22.2 0.0 0.00047 19.4 0.0 1.9 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAK68031.1 - 0.0027 16.8 0.0 2.8 7.0 0.0 3.2 1 1 2 3 3 3 2 Squalene-hopene cyclase N-terminal domain MutS_V PF00488.21 GAK68032.1 - 5.6e-61 205.8 0.3 1.2e-60 204.8 0.3 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAK68032.1 - 2.1e-36 126.0 2.4 4.4e-36 124.9 2.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAK68032.1 - 5.1e-22 78.3 0.0 1.6e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 GAK68032.1 - 2.7e-12 47.2 0.0 1.4e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 GAK68032.1 - 1.7e-08 34.7 0.0 4.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV zf-C2H2 PF00096.26 GAK68033.1 - 1.1e-08 35.0 15.3 3.1e-05 24.2 1.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAK68033.1 - 2.7e-06 27.5 2.9 2.7e-06 27.5 2.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAK68033.1 - 0.00035 20.5 0.6 0.001 19.0 0.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAK68033.1 - 0.0018 19.0 1.0 0.0018 19.0 1.0 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 GAK68033.1 - 0.0021 18.4 2.6 0.016 15.6 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAK68033.1 - 0.0021 18.3 0.1 0.0021 18.3 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 GAK68033.1 - 0.058 14.0 13.7 0.13 12.9 0.3 3.3 1 1 2 3 3 3 0 FOXP coiled-coil domain tRNA-synt_2 PF00152.20 GAK68035.1 - 1.1e-76 257.9 0.1 1.4e-76 257.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAK68035.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAK68035.1 - 0.096 12.1 0.2 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) RRM_1 PF00076.22 GAK68036.1 - 0.00031 20.5 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase02_C PF12123.8 GAK68036.1 - 0.076 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase SPX PF03105.19 GAK68036.1 - 1.2 9.0 9.4 1.5 8.7 9.4 1.2 1 0 0 1 1 1 0 SPX domain Shisa PF13908.6 GAK68036.1 - 9.8 6.4 6.9 17 5.6 6.9 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator AlaDh_PNT_N PF05222.15 GAK68037.1 - 1.7e-27 96.3 0.0 2.9e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 GAK68037.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lung_7-TM_R PF06814.13 GAK68038.1 - 4e-49 167.4 13.3 9.3e-49 166.3 13.3 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor Ribosomal_L32p PF01783.23 GAK68038.1 - 8.9e-14 51.5 4.4 1.7e-13 50.6 4.4 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 GAK68038.1 - 0.0043 16.4 1.9 0.0085 15.5 1.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 GAK68038.1 - 0.1 12.6 0.8 0.19 11.7 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbons GLTSCR1 PF15249.6 GAK68039.1 - 1.2e-10 41.7 1.9 2.1e-09 37.7 1.9 2.5 1 1 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein PEMT PF04191.13 GAK68039.1 - 0.0011 19.3 1.5 0.0021 18.4 1.5 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase AT_hook PF02178.19 GAK68039.1 - 2.5 8.3 13.3 1.6 8.8 3.7 3.5 2 0 0 2 2 2 0 AT hook motif TauD PF02668.16 GAK68042.1 - 2.7e-55 188.1 0.4 3.4e-55 187.7 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPP_enzyme_N PF02776.18 GAK68043.1 - 1.1e-33 116.3 0.1 1.9e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAK68043.1 - 3.9e-24 84.9 0.0 7.3e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAK68043.1 - 6.2e-14 52.0 0.0 3.4e-13 49.6 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aldo_ket_red PF00248.21 GAK68044.1 - 2.1e-49 168.3 0.1 1.7e-48 165.3 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family BRAP2 PF07576.12 GAK68045.1 - 3e-27 94.7 0.1 5.6e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 GAK68045.1 - 1.4e-18 67.0 5.2 1.4e-18 67.0 5.2 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 GAK68045.1 - 9.2e-08 32.3 10.1 9.2e-08 32.3 10.1 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAK68045.1 - 3.9e-06 26.6 9.5 1.1e-05 25.2 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK68045.1 - 0.00011 22.0 8.8 0.00011 22.0 8.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAK68045.1 - 0.00014 22.1 7.3 0.00014 22.1 7.3 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAK68045.1 - 0.00014 21.8 7.3 0.00041 20.3 7.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAK68045.1 - 0.00029 20.7 8.1 0.00029 20.7 8.1 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAK68045.1 - 0.00031 20.4 5.4 0.00031 20.4 5.4 2.0 2 0 0 2 2 1 1 RING-like zinc finger Phage_GP20 PF06810.11 GAK68045.1 - 0.00053 19.8 8.2 0.0009 19.1 8.2 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 zf-C3HC4_3 PF13920.6 GAK68045.1 - 0.0059 16.4 6.9 0.0059 16.4 6.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GAK68045.1 - 0.019 14.7 5.9 0.054 13.3 5.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 GAK68045.1 - 0.019 15.0 5.2 0.052 13.6 5.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cob_adeno_trans PF01923.18 GAK68045.1 - 0.054 13.6 2.6 0.11 12.6 2.6 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase RRM_1 PF00076.22 GAK68045.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UBP_var PF17807.1 GAK68045.1 - 0.21 11.4 1.3 0.47 10.3 1.3 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger BLOC1_2 PF10046.9 GAK68045.1 - 0.33 11.3 5.3 0.97 9.8 0.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MbeD_MobD PF04899.12 GAK68045.1 - 0.73 10.0 6.3 0.69 10.1 0.2 2.7 2 0 0 2 2 2 0 MbeD/MobD like DUF4407 PF14362.6 GAK68045.1 - 0.78 9.0 11.5 1.7 8.0 11.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HSBP1 PF06825.12 GAK68045.1 - 1.2 9.1 3.0 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Tho2 PF11262.8 GAK68045.1 - 1.7 7.8 4.0 2.6 7.1 4.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF724 PF05266.14 GAK68045.1 - 3.8 7.3 7.6 2.5 7.9 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMF_TATA_bd PF12325.8 GAK68045.1 - 4.5 7.5 13.2 72 3.6 13.0 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 GAK68045.1 - 4.6 7.9 7.3 2 9.1 2.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 GAK68045.1 - 7.6 6.4 11.1 18 5.2 3.0 3.1 2 1 1 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 GAK68045.1 - 9 6.3 10.3 15 5.6 10.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CDC14 PF08045.11 GAK68046.1 - 0.057 12.5 0.3 0.19 10.8 0.3 1.9 1 0 0 1 1 1 0 Cell division control protein 14, SIN component GCS PF03074.16 GAK68048.1 - 4.1e-173 575.9 0.0 5.1e-173 575.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1769 PF08588.10 GAK68049.1 - 2.1e-26 91.8 0.2 5.1e-26 90.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) KH_1 PF00013.29 GAK68050.1 - 2.6e-08 33.6 0.9 1.5e-06 27.9 0.3 2.5 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 GAK68050.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein Rotamase_3 PF13616.6 GAK68050.1 - 0.21 12.2 1.4 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain PGI PF00342.19 GAK68051.1 - 3.6e-227 754.7 0.9 4.2e-227 754.5 0.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase HNH_3 PF13392.6 GAK68053.1 - 3.7e-07 29.8 0.3 9.6e-07 28.5 0.3 1.7 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.16 GAK68054.1 - 3.2e-23 82.2 42.5 4.5e-18 65.3 16.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAK68054.1 - 2.5e-05 23.8 1.3 2.5e-05 23.8 1.3 2.4 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2370 PF10176.9 GAK68054.1 - 0.0053 16.4 1.3 0.012 15.3 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) YL1 PF05764.13 GAK68054.1 - 0.04 14.0 0.2 0.059 13.5 0.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein MFS_1_like PF12832.7 GAK68054.1 - 0.39 9.5 17.7 1.8 7.3 8.3 2.9 2 1 0 2 2 2 0 MFS_1 like family GATA PF00320.27 GAK68055.1 - 1.8 8.2 4.7 3.4 7.4 0.3 2.9 2 0 0 2 2 2 0 GATA zinc finger VPS9 PF02204.18 GAK68056.1 - 2.3e-14 53.5 0.0 4.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF455 PF04305.14 GAK68057.1 - 3.4e-97 324.8 0.1 5.1e-97 324.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 GAK68057.1 - 7.5e-07 29.0 0.5 1.6e-06 28.0 0.5 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GAK68057.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain zf-C3HC4_3 PF13920.6 GAK68058.1 - 3.5e-09 36.4 5.6 8.7e-09 35.1 5.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK68058.1 - 1.1e-05 25.2 3.2 1.9e-05 24.4 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAK68058.1 - 0.00063 20.0 5.3 0.0013 19.0 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAK68058.1 - 0.00079 19.3 3.3 0.0015 18.5 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAK68058.1 - 0.002 18.0 5.6 0.019 14.8 5.6 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAK68058.1 - 0.0042 17.1 3.5 0.018 15.1 1.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAK68058.1 - 0.063 13.1 5.5 0.039 13.8 2.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RED_N PF07808.13 GAK68058.1 - 0.082 12.5 2.1 0.17 11.4 2.1 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region MKT1_C PF12246.8 GAK68060.1 - 2.8e-81 272.3 0.0 8.1e-80 267.5 0.0 2.1 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 GAK68060.1 - 6.4e-24 84.1 0.0 1.3e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 GAK68060.1 - 3.3e-07 30.7 0.0 7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Hydantoinase_A PF01968.18 GAK68061.1 - 6e-96 321.1 1.9 1.1e-95 320.2 1.9 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAK68061.1 - 2.6e-55 186.9 0.1 3.2e-53 180.1 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Pkinase PF00069.25 GAK68062.1 - 2.5e-29 102.4 0.0 4.7e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68062.1 - 1.3e-14 54.1 0.0 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAK68062.1 - 0.0061 15.9 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like MCR_gamma PF02240.16 GAK68063.1 - 0.051 12.8 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit DUF2249 PF10006.9 GAK68063.1 - 0.096 12.6 1.3 50 3.9 0.2 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2249) PAPA-1 PF04795.12 GAK68064.1 - 4.2e-27 94.8 6.1 4.2e-27 94.8 6.1 4.5 3 2 1 4 4 4 1 PAPA-1-like conserved region Ras PF00071.22 GAK68065.1 - 5.7e-35 120.3 0.1 7e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAK68065.1 - 4.5e-26 91.4 0.1 6.8e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAK68065.1 - 1.1e-07 31.4 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAK68065.1 - 1.7e-06 27.5 0.1 2.3e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 GAK68065.1 - 0.0017 17.3 0.3 0.086 11.7 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 GAK68065.1 - 0.021 14.3 0.0 2.7 7.4 0.0 2.4 2 1 0 2 2 2 0 Bacterial TniB protein TraG-D_C PF12696.7 GAK68065.1 - 0.047 13.7 0.3 0.084 12.9 0.3 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG SRPRB PF09439.10 GAK68065.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAK68065.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNB PF00773.19 GAK68066.1 - 6.8e-47 160.4 0.0 3.1e-46 158.2 0.0 1.9 1 1 0 1 1 1 1 RNB domain LtrA PF06772.11 GAK68066.1 - 1.8e-30 106.4 23.0 8.8e-17 61.3 16.0 2.5 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Trp_oprn_chp PF09534.10 GAK68066.1 - 0.02 14.7 6.0 1.5 8.6 0.0 4.2 4 0 0 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SOG2 PF10428.9 GAK68067.1 - 0.82 8.8 13.1 0.87 8.7 13.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Glypican PF01153.19 GAK68067.1 - 1.7 7.4 4.4 1.8 7.3 4.4 1.2 1 0 0 1 1 1 0 Glypican Plasmodium_Vir PF05795.11 GAK68067.1 - 1.7 7.9 3.7 1.9 7.8 3.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 GAK68067.1 - 3.4 7.5 11.5 3.8 7.3 11.5 1.1 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 GAK68067.1 - 4.3 7.0 21.0 5 6.8 21.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 GAK68067.1 - 8.7 4.8 12.3 9.8 4.6 12.3 1.1 1 0 0 1 1 1 0 Macoilin family NUDIX PF00293.28 GAK68069.1 - 0.0039 17.2 0.1 0.32 11.0 0.1 2.9 2 1 0 2 2 2 1 NUDIX domain DUF5021 PF16424.5 GAK68069.1 - 0.17 11.7 0.0 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5021) Exo_endo_phos PF03372.23 GAK68070.1 - 5.3e-08 32.7 0.0 9.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 GAK68070.1 - 0.37 11.7 7.6 0.74 10.8 0.1 5.0 6 0 0 6 6 6 0 WD domain, G-beta repeat CN_hydrolase PF00795.22 GAK68071.1 - 5.9e-55 186.4 0.2 6.8e-55 186.2 0.2 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sfi1 PF08457.10 GAK68073.1 - 3.7e-28 98.4 136.3 1.5e-22 79.9 73.3 4.0 1 1 2 3 3 3 3 Sfi1 spindle body protein PilP PF04351.13 GAK68073.1 - 0.073 13.0 0.4 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilP Pkinase PF00069.25 GAK68077.1 - 2.5e-67 227.0 0.0 3.6e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68077.1 - 7.9e-44 149.9 0.0 1.6e-43 148.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 GAK68077.1 - 1e-20 73.9 0.0 1.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 GAK68077.1 - 5.8e-10 39.5 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAK68077.1 - 3.1e-08 33.6 0.0 7.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 GAK68077.1 - 1.1e-06 28.3 0.0 5.6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like SAM_4 PF18017.1 GAK68077.1 - 0.0031 17.4 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 GAK68077.1 - 0.021 13.6 0.0 0.057 12.2 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase RA PF00788.23 GAK68077.1 - 0.086 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Kdo PF06293.14 GAK68077.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThuA PF06283.11 GAK68078.1 - 4.5e-56 190.4 2.5 5.7e-56 190.0 2.5 1.1 1 0 0 1 1 1 1 Trehalose utilisation UTP15_C PF09384.10 GAK68080.1 - 1.7e-46 157.5 0.0 2.8e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 GAK68080.1 - 1.4e-26 92.2 2.6 1.7e-07 31.8 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68080.1 - 1.5e-06 28.4 0.0 0.56 10.5 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK68080.1 - 0.003 16.6 0.0 0.17 10.8 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_18 PF00704.28 GAK68081.1 - 2.6e-87 293.5 3.0 3.3e-87 293.1 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PRCC PF10253.9 GAK68081.1 - 0.025 15.4 3.1 0.039 14.7 3.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FAM101 PF15068.6 GAK68081.1 - 1 9.3 3.1 1.8 8.4 3.1 1.4 1 0 0 1 1 1 0 FAM101 family QRPTase_C PF01729.19 GAK68082.1 - 1e-44 152.3 0.1 1.7e-44 151.5 0.1 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain TP6A_N PF04406.14 GAK68082.1 - 7.5e-21 73.9 0.1 1.3e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase QRPTase_N PF02749.16 GAK68082.1 - 5.9e-17 61.5 0.0 2.2e-16 59.6 0.0 2.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain KDGP_aldolase PF07071.11 GAK68082.1 - 0.04 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 KDGP aldolase PAP2 PF01569.21 GAK68083.1 - 8.4e-31 106.6 1.6 8.4e-31 106.6 1.6 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 GAK68083.1 - 0.018 14.7 13.7 0.013 15.1 9.8 2.6 2 1 0 2 2 2 0 PAP2 superfamily Saf_2TM PF18303.1 GAK68083.1 - 0.018 14.6 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Colicin_V PF02674.16 GAK68083.1 - 0.12 12.3 4.5 6.6 6.7 0.0 2.6 3 0 0 3 3 3 0 Colicin V production protein Ytca PF17090.5 GAK68083.1 - 2.3 8.8 5.9 0.39 11.3 0.3 2.6 3 1 0 3 3 3 0 Uncharacterised protein family APG6 PF04111.12 GAK68084.1 - 7.6e-63 211.7 0.0 1.4e-62 210.8 0.0 1.5 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 GAK68084.1 - 3.6e-34 118.2 12.7 5.8e-34 117.5 12.7 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region HCMV_UL139 PF12507.8 GAK68084.1 - 0.035 14.5 1.6 0.077 13.4 1.6 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Metal_resist PF13801.6 GAK68084.1 - 5.5 7.2 16.3 8.6 6.6 14.6 2.3 2 0 0 2 2 2 0 Heavy-metal resistance Ribonucleas_3_3 PF14622.6 GAK68085.1 - 3.3e-30 104.9 0.0 4.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAK68085.1 - 2.6e-05 24.8 0.0 4.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain HAMP PF00672.25 GAK68085.1 - 0.18 12.2 1.5 0.4 11.1 1.5 1.6 1 0 0 1 1 1 0 HAMP domain eIF3g PF12353.8 GAK68086.1 - 1.4e-44 151.4 5.2 2.5e-44 150.7 5.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 GAK68086.1 - 4.1e-19 68.2 0.0 7.4e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAK68086.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif vATP-synt_E PF01991.18 GAK68087.1 - 1.6e-61 207.2 14.4 1.9e-61 207.0 14.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Ran_BP1 PF00638.18 GAK68088.1 - 4.7e-22 78.5 0.1 9.7e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain hDGE_amylase PF14701.6 GAK68089.1 - 1.2e-169 565.1 0.1 1.7e-169 564.6 0.1 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 GAK68089.1 - 1.6e-116 389.4 0.1 2.6e-116 388.7 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 GAK68089.1 - 3.8e-81 272.5 0.0 6.6e-81 271.7 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 GAK68089.1 - 2.4e-18 66.0 0.1 4.9e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 GAK68089.1 - 0.1 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Peptidase_S10 PF00450.22 GAK68090.1 - 2.5e-97 326.9 4.5 4.3e-97 326.2 4.5 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Ribosomal_L33 PF00471.20 GAK68090.1 - 3.3e-11 43.4 0.0 1.1e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L33 ABC_membrane_2 PF06472.15 GAK68093.1 - 7.4e-93 310.8 2.4 7.4e-93 310.8 2.4 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAK68093.1 - 7e-16 59.0 0.0 2.2e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.12 GAK68093.1 - 0.0036 17.1 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAK68093.1 - 0.0047 17.3 0.1 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAK68093.1 - 0.0084 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAK68093.1 - 0.028 14.1 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 GAK68093.1 - 0.031 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 GAK68093.1 - 0.055 14.0 0.6 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 GAK68093.1 - 0.097 10.2 0.0 0.16 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_21 PF13304.6 GAK68093.1 - 0.098 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 GAK68093.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.19 GAK68093.1 - 0.16 11.4 0.0 12 5.3 0.1 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 GAK68093.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region EGF_CA PF07645.15 GAK68094.1 - 0.071 13.3 0.5 0.17 12.2 0.5 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain MFS_1 PF07690.16 GAK68096.1 - 3.7e-29 101.8 42.8 3.7e-29 101.8 42.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily His_Phos_2 PF00328.22 GAK68097.1 - 5.2e-47 161.0 0.0 7.9e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 GAK68098.1 - 2.4e-22 79.3 0.0 8.5e-21 74.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK68098.1 - 2.8e-18 66.3 0.0 3.4e-17 62.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3984 PF13136.6 GAK68098.1 - 0.038 13.4 1.1 0.051 13.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) 3HCDH_N PF02737.18 GAK68098.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_Rpb6 PF01192.22 GAK68099.1 - 6.6e-18 64.4 0.1 1e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Chitin_synth_1 PF01644.17 GAK68100.1 - 3e-69 232.1 0.1 4.6e-69 231.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAK68100.1 - 1.9e-23 82.2 0.0 5.9e-23 80.6 0.0 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAK68100.1 - 1.7e-22 79.8 0.0 5.5e-18 64.9 0.0 2.5 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAK68100.1 - 2.4e-11 43.9 0.3 2.4e-11 43.9 0.3 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 CitMHS PF03600.16 GAK68100.1 - 0.0023 17.2 2.0 0.004 16.4 2.0 1.4 1 0 0 1 1 1 1 Citrate transporter Glyco_tranf_2_3 PF13641.6 GAK68100.1 - 0.085 12.7 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF1218 PF06749.12 GAK68100.1 - 9.9 6.8 7.6 43 4.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Tautomerase_3 PF14832.6 GAK68101.1 - 2.2e-41 141.3 0.0 2.8e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Zn_clus PF00172.18 GAK68102.1 - 1.1e-05 25.5 15.3 1.1e-05 25.5 15.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEX11 PF05648.14 GAK68103.1 - 3.6e-67 226.1 2.8 4e-67 225.9 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HemX PF04375.14 GAK68104.1 - 0.00047 19.6 0.2 0.0005 19.4 0.2 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase WD40 PF00400.32 GAK68105.1 - 3.8e-16 59.2 10.7 0.00051 20.8 0.8 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68105.1 - 5.8e-05 23.3 0.0 16 5.9 0.0 5.8 5 1 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAK68105.1 - 0.0012 17.7 0.0 1.4 7.6 0.0 2.8 2 0 0 2 2 2 2 Nup133 N terminal like GTP_EFTU PF00009.27 GAK68106.1 - 8e-67 224.5 0.2 1.2e-66 224.0 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAK68106.1 - 2e-32 111.5 0.0 5.7e-32 110.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 GAK68106.1 - 1.7e-21 76.0 0.0 3.9e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAK68106.1 - 4.8e-14 52.5 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAK68106.1 - 1.7e-13 50.5 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAK68106.1 - 1.9e-05 24.7 0.1 3.8e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ECH_2 PF16113.5 GAK68107.1 - 1.9e-88 297.2 1.3 1.1e-64 219.1 0.1 3.1 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAK68107.1 - 7e-21 74.7 4.1 5.6e-11 42.2 0.1 2.9 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase KAR9 PF08580.10 GAK68108.1 - 0.35 9.3 1.5 0.48 8.9 1.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DMRL_synthase PF00885.19 GAK68110.1 - 7.4e-51 171.7 0.0 9.1e-51 171.4 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase GST_C PF00043.25 GAK68111.1 - 6.3e-11 42.4 0.0 1.4e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAK68111.1 - 2.5e-10 40.6 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAK68111.1 - 5.7e-09 36.1 0.0 9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAK68111.1 - 1.2e-08 35.2 0.1 2e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAK68111.1 - 2.3e-05 24.3 0.0 5.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAK68111.1 - 0.0054 17.0 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAK68111.1 - 0.027 14.2 0.0 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NAC PF01849.18 GAK68112.1 - 1e-21 76.6 0.0 1.8e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 NAC domain ATP-synt_E PF05680.12 GAK68113.1 - 5.1e-21 74.8 0.3 5.3e-21 74.8 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain 5_nucleotid_C PF02872.18 GAK68114.1 - 0.066 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain WES_acyltransf PF03007.16 GAK68116.1 - 1.8e-14 54.1 0.0 1.8e-14 54.1 0.0 2.0 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 GAK68116.1 - 3e-11 43.5 0.0 1.2e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1298) WD40 PF00400.32 GAK68117.1 - 2.8e-36 122.9 21.7 9e-09 35.8 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 GAK68117.1 - 3.1e-27 95.4 0.0 6.4e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 GAK68117.1 - 4.4e-09 36.5 0.0 0.021 15.1 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK68117.1 - 0.0034 16.4 0.0 4 6.3 0.0 3.9 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Metallophos PF00149.28 GAK68118.1 - 1.3e-39 136.8 0.1 1.8e-39 136.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAK68118.1 - 1.3e-20 73.6 0.3 2.8e-20 72.5 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Rad51 PF08423.11 GAK68119.1 - 1.7e-21 76.7 0.1 9.1e-11 41.5 0.0 2.6 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.6 GAK68119.1 - 1.6e-05 24.5 1.2 6.4e-05 22.6 1.2 2.0 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 GAK68119.1 - 0.00036 20.1 0.4 0.089 12.2 0.1 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 GAK68119.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 GAK68119.1 - 0.0019 17.6 0.3 0.0054 16.1 0.0 1.8 2 0 0 2 2 2 1 KaiC DUF4167 PF13763.6 GAK68119.1 - 0.11 12.6 1.0 0.21 11.8 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Amino_oxidase PF01593.24 GAK68120.1 - 9.7e-15 54.8 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK68120.1 - 1.8e-08 34.5 0.1 3.6e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAK68120.1 - 0.0049 16.1 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK68120.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAK68120.1 - 0.041 13.1 0.3 0.083 12.1 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAK68120.1 - 0.053 13.5 0.1 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 GAK68120.1 - 0.11 12.7 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 GAK68120.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAK68120.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Hexokinase_2 PF03727.16 GAK68121.1 - 9.8e-79 264.2 0.1 1.9e-78 263.2 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 GAK68121.1 - 1.5e-65 220.8 0.0 2.4e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase YjgF_endoribonc PF14588.6 GAK68121.1 - 0.098 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Aldo_ket_red PF00248.21 GAK68122.1 - 1.5e-41 142.5 0.0 3.8e-40 137.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family AA_permease PF00324.21 GAK68124.1 - 4.8e-133 444.2 37.2 5.8e-133 444.0 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAK68124.1 - 2.1e-35 122.4 40.4 2.9e-35 122.0 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.6 GAK68124.1 - 1.4e-33 116.7 0.1 1.1e-32 113.8 0.0 2.1 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 GAK68124.1 - 2.5e-05 23.9 0.6 0.00011 21.8 0.1 2.2 2 1 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 GAK68124.1 - 0.0058 17.0 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SID-1_RNA_chan PF13965.6 GAK68124.1 - 0.17 10.2 3.7 0.26 9.7 0.5 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 G-patch_2 PF12656.7 GAK68125.1 - 6.1e-23 80.7 2.2 2.3e-22 78.9 2.2 2.1 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 GAK68125.1 - 7.9e-05 22.5 7.1 0.00014 21.6 7.1 1.5 1 0 0 1 1 1 1 G-patch domain DUF747 PF05346.11 GAK68127.1 - 3.2e-118 394.8 3.8 4.2e-118 394.4 3.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF755 PF05501.11 GAK68129.1 - 4.5 7.6 13.6 0.097 12.9 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) tRNA_m1G_MT PF01746.21 GAK68130.1 - 9.6e-20 71.1 0.1 4.1e-15 56.0 0.1 3.1 2 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Dcc1 PF09724.9 GAK68131.1 - 1.3e-77 261.4 0.0 1.5e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 AbiEi_3 PF11459.8 GAK68131.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system bZIP_1 PF00170.21 GAK68133.1 - 1.6e-05 24.9 17.4 1.6e-05 24.9 17.4 2.0 2 1 0 2 2 2 1 bZIP transcription factor Kinesin_assoc PF16183.5 GAK68133.1 - 0.1 12.7 0.1 1.6 8.9 0.0 2.9 2 1 0 2 2 2 0 Kinesin-associated Ldh_1_C PF02866.18 GAK68134.1 - 1.8e-45 154.9 0.0 3e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAK68134.1 - 2.6e-42 144.3 0.2 1.5e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAK68134.1 - 0.0041 16.2 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 GAK68134.1 - 0.0088 15.6 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 GAK68134.1 - 0.16 11.3 0.6 2 7.7 0.1 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.21 GAK68135.1 - 2.5e-49 168.1 0.0 3.3e-47 161.1 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family HEPN_SAV_6107 PF18726.1 GAK68135.1 - 0.92 10.1 7.6 2 8.9 5.6 2.5 3 0 0 3 3 3 0 SAV_6107-like HEPN Dioxygenase_C PF00775.21 GAK68138.1 - 1.4e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase p450 PF00067.22 GAK68139.1 - 1.2e-28 100.1 0.0 2.2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAK68140.1 - 7.4e-12 44.8 23.9 7.4e-12 44.8 23.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Lactamase_B_2 PF12706.7 GAK68141.1 - 1.8e-26 93.0 0.0 2.7e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAK68141.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 GAK68141.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Sel1 PF08238.12 GAK68142.1 - 3.8e-14 52.8 8.3 0.0022 18.6 0.3 6.0 6 0 0 6 6 6 4 Sel1 repeat DUF4129 PF13559.6 GAK68142.1 - 0.39 11.0 10.1 2.5 8.4 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4129) Ipi1_N PF12333.8 GAK68143.1 - 3.9e-16 59.5 1.3 4.6e-15 56.1 0.0 3.3 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 GAK68143.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.9 4 0 0 4 4 4 0 HEAT-like repeat Complex1_LYR PF05347.15 GAK68144.1 - 0.14 12.2 3.0 0.43 10.7 2.1 2.3 2 1 0 2 2 2 0 Complex 1 protein (LYR family) eIF2A PF08662.11 GAK68145.1 - 6.9e-40 137.0 0.0 1.1e-34 120.1 0.0 4.4 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GAK68145.1 - 1.5e-05 24.8 0.1 3.6e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 GAK68145.1 - 0.017 16.0 4.3 1.5 9.8 0.1 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat AAA_32 PF13654.6 GAK68145.1 - 0.09 11.5 7.0 0.13 11.0 7.0 1.2 1 0 0 1 1 1 0 AAA domain Metal_resist PF13801.6 GAK68145.1 - 0.42 10.8 11.0 0.88 9.8 0.2 2.5 1 1 1 2 2 2 0 Heavy-metal resistance ApoLp-III PF07464.11 GAK68145.1 - 0.73 9.9 3.5 1.4 9.0 3.5 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) 4HB_MCP_1 PF12729.7 GAK68145.1 - 1.4 8.4 8.1 2.5 7.6 8.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Spb1_C PF07780.12 GAK68146.1 - 2.3e-80 269.2 21.6 2.3e-80 269.2 21.6 3.9 4 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 GAK68146.1 - 4.2e-55 186.6 0.1 1.8e-54 184.5 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 GAK68146.1 - 4.5e-47 159.9 9.5 4.5e-47 159.9 9.5 5.7 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) DUF148 PF02520.17 GAK68146.1 - 0.072 13.2 5.3 0.049 13.7 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF1751 PF08551.10 GAK68147.1 - 1.1e-27 96.5 3.8 2.1e-27 95.6 3.8 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) LRR_6 PF13516.6 GAK68147.1 - 2.2e-07 30.4 17.4 0.73 10.0 0.0 8.2 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 GAK68147.1 - 0.014 15.8 18.1 0.1 13.0 1.8 6.0 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAK68147.1 - 0.021 15.3 5.0 19 6.3 0.0 5.7 6 1 0 6 6 6 0 Leucine Rich Repeat AWPM-19 PF05512.11 GAK68147.1 - 0.067 13.4 0.6 0.15 12.2 0.6 1.6 1 0 0 1 1 1 0 AWPM-19-like family CDC45 PF02724.14 GAK68147.1 - 2.6 6.2 10.7 4.2 5.5 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAK68147.1 - 5.9 5.0 12.8 9 4.4 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family GCIP PF13324.6 GAK68147.1 - 9.9 5.7 9.9 19 4.7 9.9 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Glutaredoxin PF00462.24 GAK68148.1 - 5.6e-14 52.1 0.0 8.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 GAK68148.1 - 9.9e-05 22.7 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 GAK68148.1 - 0.0024 18.3 0.1 0.0032 17.9 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 GAK68148.1 - 0.0066 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin PF00085.20 GAK68148.1 - 0.02 14.9 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.20 GAK68148.1 - 0.04 13.7 0.1 0.083 12.6 0.1 1.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF953 PF06110.11 GAK68148.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.6 GAK68148.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF4597 PF15366.6 GAK68149.1 - 0.27 11.0 1.5 0.86 9.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) PIG-P PF08510.12 GAK68149.1 - 0.88 9.5 3.0 5.4 7.0 0.3 2.8 3 0 0 3 3 3 0 PIG-P Pkinase PF00069.25 GAK68150.1 - 4e-68 229.6 0.0 5e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68150.1 - 3e-26 92.3 0.0 4.2e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK68150.1 - 0.24 10.1 0.0 0.46 9.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Slu7 PF11708.8 GAK68151.1 - 2.6e-101 338.9 19.6 2.6e-101 338.9 19.6 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF1823 PF08853.11 GAK68153.1 - 0.067 13.4 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) Surp PF01805.20 GAK68153.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Surp module MAD PF05557.13 GAK68154.1 - 1e-47 162.9 44.0 1.2e-46 159.4 44.0 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Shugoshin_N PF07558.11 GAK68154.1 - 0.00024 20.9 1.2 5.6 6.9 0.0 5.2 5 0 0 5 5 5 1 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.11 GAK68154.1 - 0.00079 19.8 10.6 2.7 8.4 0.0 6.8 5 2 3 8 8 8 1 Flagella accessory protein C (FlaC) ATG16 PF08614.11 GAK68154.1 - 0.0016 18.7 17.1 0.0016 18.7 17.1 5.1 4 1 0 4 4 4 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAK68154.1 - 0.0025 16.7 10.2 0.0025 16.7 10.2 5.8 3 2 2 6 6 6 3 Spc7 kinetochore protein APG6_N PF17675.1 GAK68154.1 - 0.0073 16.8 8.0 0.0073 16.8 8.0 6.1 3 3 3 6 6 6 2 Apg6 coiled-coil region HALZ PF02183.18 GAK68154.1 - 0.02 15.1 27.5 2.2 8.6 0.3 7.9 8 0 0 8 8 8 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 GAK68154.1 - 0.039 14.4 11.3 0.63 10.5 0.2 5.6 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 GAK68154.1 - 0.044 13.6 53.8 0.58 10.0 0.1 10.6 6 2 6 12 12 11 0 Septum formation initiator YabA PF06156.13 GAK68154.1 - 0.073 13.7 31.0 5 7.8 3.1 6.6 3 3 3 6 6 6 0 Initiation control protein YabA DUF1664 PF07889.12 GAK68154.1 - 0.18 11.9 22.1 0.35 10.9 0.3 5.6 5 1 0 5 5 5 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAK68154.1 - 0.21 11.7 22.3 3 8.0 0.7 5.5 3 2 3 6 6 6 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 GAK68154.1 - 0.52 10.4 40.6 8.6 6.5 0.9 9.2 6 3 4 10 10 10 0 bZIP transcription factor APC_N_CC PF16689.5 GAK68154.1 - 1.7 8.7 8.3 21 5.2 0.1 4.6 3 1 1 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain DUF4407 PF14362.6 GAK68154.1 - 3.4 6.9 59.7 0.17 11.2 6.9 4.8 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 GAK68154.1 - 7.2 6.7 51.2 0.076 13.0 0.7 8.8 6 3 3 9 9 9 0 TATA element modulatory factor 1 DNA binding BTB_2 PF02214.22 GAK68155.1 - 1e-06 29.0 0.0 0.024 15.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Prenyltrans PF00432.21 GAK68157.1 - 4.3e-50 167.1 7.5 7.3e-11 41.6 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAK68157.1 - 6.5e-05 22.2 0.0 0.00047 19.4 0.0 1.9 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAK68157.1 - 0.0027 16.8 0.0 2.8 7.0 0.0 3.2 1 1 2 3 3 3 2 Squalene-hopene cyclase N-terminal domain Acetyltransf_1 PF00583.25 GAK68158.1 - 8.9e-08 32.4 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAK68158.1 - 8.7e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAK68158.1 - 1.9e-06 27.8 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAK68158.1 - 0.0001 22.7 0.1 0.00019 21.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAK68158.1 - 0.0026 17.9 0.2 0.0042 17.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNA_pol_Rpb2_6 PF00562.28 GAK68160.1 - 1.5e-124 416.0 0.3 2.9e-124 415.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAK68160.1 - 1e-65 221.1 0.0 1.5e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAK68160.1 - 4.4e-49 166.7 0.0 1.3e-48 165.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAK68160.1 - 1.6e-30 105.4 0.1 7.3e-30 103.2 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 GAK68160.1 - 8.5e-25 86.7 0.1 2.4e-24 85.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GAK68160.1 - 8e-23 80.5 1.3 1.6e-22 79.6 0.4 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 GAK68160.1 - 3.2e-20 72.4 0.4 9.4e-20 70.9 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CWC25 PF12542.8 GAK68161.1 - 8.8e-26 90.8 1.0 8.8e-26 90.8 1.0 4.5 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 GAK68161.1 - 6.7e-12 45.4 14.0 6.7e-12 45.4 14.0 5.5 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR BTB PF00651.31 GAK68162.1 - 5.9e-09 36.1 0.0 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain ABC2_membrane PF01061.24 GAK68163.1 - 1.7e-44 151.8 20.2 2.8e-44 151.1 20.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAK68163.1 - 4.3e-23 82.3 0.0 7.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAK68163.1 - 5.7e-05 22.4 15.2 5.7e-05 22.4 15.2 1.9 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 GAK68163.1 - 0.0015 19.0 0.4 0.0056 17.1 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 GAK68163.1 - 0.0015 18.4 0.8 1.2 8.9 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAK68163.1 - 0.0024 17.4 0.2 0.018 14.6 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAK68163.1 - 0.0064 16.8 0.0 0.27 11.5 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAK68163.1 - 0.016 15.8 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAK68163.1 - 0.025 14.5 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 GAK68163.1 - 0.037 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAK68163.1 - 0.13 12.1 0.2 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAK68163.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zn_clus PF00172.18 GAK68165.1 - 0.16 12.1 13.6 0.057 13.5 5.7 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhodanese_C PF12368.8 GAK68165.1 - 4.2 7.8 9.0 9.9 6.6 9.0 1.6 1 1 0 1 1 1 0 Rhodanase C-terminal Pkinase PF00069.25 GAK68166.1 - 4.6e-73 245.8 0.0 5.5e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68166.1 - 1.6e-31 109.5 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK68166.1 - 5.9e-05 22.5 0.1 0.0043 16.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 GAK68166.1 - 0.0087 15.0 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 GAK68166.1 - 0.029 14.3 0.9 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAK68167.1 - 1e-35 123.3 0.0 1.1e-22 80.7 0.0 2.9 3 0 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.23 GAK68167.1 - 8.9e-05 22.5 0.2 0.056 13.4 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family PPP4R2 PF09184.11 GAK68167.1 - 1 8.9 2.8 2.1 7.9 2.8 1.4 1 0 0 1 1 1 0 PPP4R2 Hira PF07569.11 GAK68169.1 - 1.4e-50 172.1 0.0 3.1e-50 171.0 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 GAK68169.1 - 1.1e-23 83.0 23.8 2.5e-06 28.1 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68169.1 - 3.7e-10 40.0 0.5 0.44 10.9 0.0 6.0 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 GAK68169.1 - 6.6e-09 35.4 1.7 1.9e-08 33.9 1.7 1.8 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 GAK68169.1 - 0.0081 15.2 1.0 8.6 5.2 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAK68169.1 - 0.022 14.7 3.3 0.76 9.8 0.3 3.4 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat Semialdhyde_dhC PF02774.18 GAK68170.1 - 2.9e-44 151.3 0.0 4.5e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GAK68170.1 - 5.3e-27 94.7 0.0 1.1e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAK68170.1 - 0.004 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 GAK68170.1 - 0.033 14.9 0.0 0.086 13.6 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Gp_dh_C PF02800.20 GAK68170.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CTP_transf_1 PF01148.20 GAK68171.1 - 0.0038 17.0 0.6 0.0053 16.6 0.6 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Glyco_hydro_43 PF04616.14 GAK68172.1 - 7.3e-17 61.6 0.0 8.4e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 tRNA_U5-meth_tr PF05958.11 GAK68173.1 - 5.5e-23 81.5 0.0 1.2e-21 77.1 0.0 2.5 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAK68173.1 - 7.7e-10 38.8 0.0 1.7e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK68173.1 - 1.2e-06 29.1 0.0 3.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 GAK68173.1 - 4.4e-06 26.4 0.0 8.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 GAK68173.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 GAK68173.1 - 0.0003 21.4 0.0 0.00093 19.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAK68173.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) SR-25 PF10500.9 GAK68173.1 - 0.0059 16.2 4.3 0.0096 15.6 4.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Met_10 PF02475.16 GAK68173.1 - 0.0081 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 GAK68173.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TPMT PF05724.11 GAK68173.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 GAK68173.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family IF4E PF01652.18 GAK68177.1 - 1.2e-45 155.1 0.0 1.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ADH_zinc_N PF00107.26 GAK68178.1 - 1.2e-24 86.8 0.0 6.7e-23 81.1 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAK68178.1 - 3.5e-16 60.5 0.0 7.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAK68178.1 - 1.2e-10 41.2 0.4 2.9e-10 40.0 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 GAK68178.1 - 0.0023 17.4 0.4 0.0035 16.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Peripla_BP_6 PF13458.6 GAK68178.1 - 0.042 13.5 0.0 0.042 13.5 0.0 1.8 3 0 0 3 3 3 0 Periplasmic binding protein Biotin_carb_N PF00289.22 GAK68178.1 - 0.057 14.0 0.2 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 Biotin carboxylase, N-terminal domain AMP-binding PF00501.28 GAK68179.1 - 1.1e-93 314.2 0.0 1.3e-93 313.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAK68179.1 - 5.8e-28 97.7 2.1 1.4e-26 93.3 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAK68179.1 - 3e-16 59.1 0.3 7.6e-16 57.8 0.3 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus OCD_Mu_crystall PF02423.15 GAK68181.1 - 5.7e-25 87.9 0.8 1.1e-24 87.0 0.8 1.4 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PI3_PI4_kinase PF00454.27 GAK68182.1 - 4.9e-33 115.0 0.0 1.8e-32 113.1 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAK68182.1 - 6.2e-05 22.5 0.4 0.00012 21.5 0.4 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.8 GAK68182.1 - 0.0026 17.7 0.1 0.0069 16.3 0.1 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 FAT PF02259.23 GAK68183.1 - 1.4e-67 228.4 7.3 1.4e-67 228.4 7.3 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 GAK68183.1 - 1.5e-24 87.2 0.0 3e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAK68183.1 - 0.0017 18.1 0.0 0.005 16.6 0.0 1.8 1 0 0 1 1 1 1 FATC domain VapB_antitoxin PF09957.9 GAK68183.1 - 0.1 12.5 0.0 2.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial antitoxin of type II TA system, VapB DASH_Dad2 PF08654.10 GAK68183.1 - 0.11 13.0 0.5 2 8.9 0.0 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad2 DED PF01335.21 GAK68183.1 - 0.21 11.9 1.1 55 4.2 0.2 3.6 2 0 0 2 2 2 0 Death effector domain RasGEF_N_2 PF14663.6 GAK68183.1 - 3.3 8.1 8.2 1.8 9.0 0.2 4.7 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Rad4 PF03835.15 GAK68184.1 - 1.9e-27 95.7 0.2 5.7e-27 94.2 0.2 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 GAK68184.1 - 1.1e-26 93.0 0.1 2.6e-26 91.8 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 GAK68184.1 - 2.6e-15 57.1 0.4 2.6e-15 57.1 0.4 4.8 5 1 0 5 5 5 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 GAK68184.1 - 1.4e-13 50.4 0.0 3.2e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 GAK68184.1 - 5.3e-08 33.3 0.1 1.8e-05 25.1 0.0 3.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Transketolase_N PF00456.21 GAK68185.1 - 2.4e-13 49.8 0.1 2.6e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DUF726 PF05277.12 GAK68186.1 - 6.8e-116 386.9 1.3 9.9e-116 386.4 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 GAK68186.1 - 0.033 13.8 0.7 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold SRP14 PF02290.15 GAK68187.1 - 4e-20 72.0 0.0 4e-20 72.0 0.0 2.3 2 1 0 2 2 2 1 Signal recognition particle 14kD protein bVLRF1 PF18826.1 GAK68188.1 - 1.1e-47 161.6 0.4 2.4e-47 160.5 0.0 1.8 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor TPR_16 PF13432.6 GAK68189.1 - 0.00062 20.4 4.0 0.0024 18.5 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Histone_HNS PF00816.21 GAK68189.1 - 0.011 16.5 3.3 2.9 8.8 0.9 2.9 3 0 0 3 3 3 0 H-NS histone family ABATE PF07336.11 GAK68189.1 - 0.047 14.4 2.4 0.073 13.7 2.0 1.7 1 1 0 1 1 1 0 Putative stress-induced transcription regulator TPR_2 PF07719.17 GAK68189.1 - 0.052 13.7 1.1 19 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAK68189.1 - 0.093 12.6 0.1 7 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAK68189.1 - 0.46 10.7 4.2 1.5 9.0 2.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK68189.1 - 0.84 10.6 5.7 0.55 11.2 0.9 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat IPK PF03770.16 GAK68190.1 - 2.9e-38 131.7 0.0 5.9e-37 127.4 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase PH_4 PF15404.6 GAK68191.1 - 1.5e-45 155.3 0.7 1.3e-44 152.2 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Ribosom_S12_S23 PF00164.25 GAK68192.1 - 3.1e-36 123.4 0.8 4.1e-36 123.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ChAPs PF09295.10 GAK68193.1 - 2.9e-157 523.7 0.0 4.6e-157 523.1 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 GAK68193.1 - 1.6e-07 31.7 0.2 0.0019 18.7 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK68193.1 - 0.0012 19.0 4.2 0.011 15.9 1.3 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAK68193.1 - 0.0012 19.3 0.3 43 5.0 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAK68193.1 - 0.016 15.3 4.9 9.8 6.6 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat Flagellin_IN PF07196.13 GAK68193.1 - 0.27 11.5 3.8 8 6.8 1.7 2.6 2 0 0 2 2 2 0 Flagellin hook IN motif TPR_14 PF13428.6 GAK68193.1 - 0.34 11.8 11.9 4.7 8.3 0.0 5.8 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAK68193.1 - 0.67 9.1 9.9 0.48 9.6 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0203 PF05254.12 GAK68195.1 - 2.5e-21 75.7 2.5 1.4e-20 73.3 2.5 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 GAK68195.1 - 0.0012 19.0 0.4 0.99 9.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein P33MONOX PF15302.6 GAK68195.1 - 0.0032 17.2 1.0 0.0039 17.0 1.0 1.2 1 0 0 1 1 1 1 P33 mono-oxygenase IMUP PF15761.5 GAK68195.1 - 0.0073 17.0 5.2 0.0073 17.0 5.2 2.4 2 0 0 2 2 2 1 Immortalisation up-regulated protein NDUF_B7 PF05676.13 GAK68195.1 - 0.024 14.3 1.2 4.2 7.2 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ndufs5 PF10200.9 GAK68195.1 - 0.15 12.3 0.2 0.33 11.2 0.1 1.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF5339 PF17274.2 GAK68195.1 - 0.36 11.7 2.9 0.4 11.6 0.2 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Arf PF00025.21 GAK68196.1 - 1.1e-66 223.7 0.0 1.2e-65 220.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 GAK68196.1 - 3.4e-10 39.6 0.1 2.6e-06 26.9 0.0 3.2 2 1 1 3 3 3 2 G-protein alpha subunit SRPRB PF09439.10 GAK68196.1 - 4.7e-09 35.9 0.0 2.7e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAK68196.1 - 1e-08 35.4 0.0 5.1e-07 29.9 0.0 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAK68196.1 - 3.9e-08 33.4 0.1 1.6e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 GAK68196.1 - 9.2e-08 31.9 0.1 2.2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Ras family PRK PF00485.18 GAK68196.1 - 4e-06 26.7 0.0 1.6e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Gtr1_RagA PF04670.12 GAK68196.1 - 9.9e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 GAK68196.1 - 0.00027 21.5 0.4 0.25 11.9 0.8 3.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAK68196.1 - 0.00049 20.6 0.0 0.24 11.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 GAK68196.1 - 0.002 17.7 0.4 4.4 6.8 0.1 3.0 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAK68196.1 - 0.0073 16.1 0.7 0.52 10.0 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 GAK68196.1 - 0.0077 16.5 0.2 1.3 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAK68196.1 - 0.013 15.6 0.3 2.3 8.4 0.2 3.2 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 GAK68196.1 - 0.051 13.5 0.2 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 GAK68196.1 - 0.051 12.6 0.4 0.2 10.7 0.2 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 GAK68196.1 - 0.09 12.4 0.8 7.2 6.2 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 GAK68196.1 - 0.098 12.6 0.2 15 5.4 0.1 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_16 PF13191.6 GAK68196.1 - 0.11 12.8 0.8 2.3 8.6 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 GAK68196.1 - 0.71 9.7 2.4 11 5.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IF4E PF01652.18 GAK68197.1 - 4e-50 169.7 0.0 5.4e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TAF8_C PF10406.9 GAK68198.1 - 9.9e-07 29.2 6.4 0.00062 20.3 1.2 2.8 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 GAK68198.1 - 8.3e-06 25.7 0.1 1.4e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Rhodanese PF00581.20 GAK68199.1 - 9.4e-10 39.0 0.0 1.5e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain HalOD1 PF18545.1 GAK68199.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Halobacterial output domain 1 ECH_1 PF00378.20 GAK68200.1 - 1.5e-33 116.2 0.1 3.1e-33 115.2 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAK68200.1 - 1.7e-14 54.1 0.5 3.7e-14 53.0 0.5 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Adenyl_cycl_N PF12633.7 GAK68201.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase NT domain Amidohydro_1 PF01979.20 GAK68202.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family adh_short_C2 PF13561.6 GAK68203.1 - 3.4e-37 128.2 0.3 4.5e-37 127.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK68203.1 - 6.8e-26 90.9 0.0 1.1e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK68203.1 - 0.00034 20.6 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAK68203.1 - 0.0094 15.3 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IlvN PF07991.12 GAK68203.1 - 0.045 13.3 0.4 0.089 12.4 0.4 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Eno-Rase_NADH_b PF12242.8 GAK68203.1 - 0.091 12.5 4.4 0.09 12.5 2.7 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Mur_ligase PF01225.25 GAK68203.1 - 0.1 12.9 0.3 1.4 9.3 0.3 2.4 2 1 0 2 2 2 0 Mur ligase family, catalytic domain Pkinase PF00069.25 GAK68204.1 - 2.2e-58 197.7 0.0 2.8e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68204.1 - 6e-21 74.9 0.0 7.2e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Elong_Iki1 PF10483.9 GAK68204.1 - 3.8e-16 59.5 0.1 5.5e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Elongator subunit Iki1 Kdo PF06293.14 GAK68204.1 - 0.00036 20.0 0.1 0.00073 19.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAK68204.1 - 0.014 14.4 0.1 0.031 13.2 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain zf-H2C2_2 PF13465.6 GAK68205.1 - 7e-07 29.4 16.2 0.00052 20.3 5.0 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAK68205.1 - 4.2e-06 26.9 23.4 0.00079 19.7 3.4 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAK68205.1 - 0.0056 17.4 16.3 0.07 14.0 1.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger eIF3_subunit PF08597.10 GAK68206.1 - 1e-51 176.2 30.0 1.2e-51 176.0 30.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit p25-alpha PF05517.12 GAK68206.1 - 0.0067 16.6 0.8 0.015 15.5 0.8 1.7 1 0 0 1 1 1 1 p25-alpha S1FA PF04689.13 GAK68206.1 - 0.08 13.1 2.0 2.7 8.2 1.5 2.8 2 0 0 2 2 2 0 DNA binding protein S1FA Response_reg PF00072.24 GAK68207.1 - 1.5e-19 70.2 0.1 3.8e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAK68207.1 - 3.8e-14 53.1 0.0 7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAK68207.1 - 2e-05 24.5 0.8 5.4e-05 23.1 0.8 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DEC-1_N PF04625.13 GAK68207.1 - 0.0018 17.3 1.3 0.0018 17.3 1.3 1.8 2 0 0 2 2 2 1 DEC-1 protein, N-terminal region F-box-like PF12937.7 GAK68208.1 - 1.2e-05 25.1 0.3 0.066 13.1 0.0 2.8 2 0 0 2 2 2 2 F-box-like TPR_2 PF07719.17 GAK68208.1 - 0.0036 17.3 0.3 0.013 15.6 0.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.33 GAK68208.1 - 0.0038 17.1 2.2 0.29 11.1 0.3 2.4 2 0 0 2 2 2 2 F-box domain TPR_11 PF13414.6 GAK68208.1 - 0.0044 16.7 0.3 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 TPR repeat MIT PF04212.18 GAK68208.1 - 0.011 15.8 0.2 0.032 14.3 0.2 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 GAK68208.1 - 0.013 15.3 0.2 0.098 12.5 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAK68208.1 - 0.015 16.0 1.0 0.082 13.8 1.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TetR_C_14 PF17754.1 GAK68208.1 - 0.14 12.2 3.0 0.33 10.9 0.1 2.8 2 1 0 3 3 3 0 MftR C-terminal domain Tubulin_3 PF14881.6 GAK68209.1 - 6.3e-33 114.0 0.1 2.5e-32 112.0 0.1 1.9 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 GAK68209.1 - 1.6e-28 99.4 0.1 3.5e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 GAK68209.1 - 0.0011 19.2 0.0 1.4 9.0 0.0 3.3 3 1 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain UBX PF00789.20 GAK68210.1 - 3.3e-07 30.4 0.0 9.9e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 GAK68210.1 - 0.00041 20.2 0.0 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Jas PF16135.5 GAK68210.1 - 0.088 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling zf-C2H2 PF00096.26 GAK68210.1 - 0.1 13.1 0.7 0.22 12.0 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 GAK68210.1 - 0.16 12.3 0.1 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 GAK68210.1 - 0.25 11.4 3.2 0.63 10.1 3.2 1.8 1 1 0 1 1 1 0 CpXC protein RskA PF10099.9 GAK68210.1 - 2.4 8.4 21.3 0.055 13.8 10.4 2.6 2 1 0 3 3 3 0 Anti-sigma-K factor rskA Atrophin-1 PF03154.15 GAK68210.1 - 8.5 4.5 19.7 14 3.8 19.7 1.3 1 0 0 1 1 1 0 Atrophin-1 family CoaE PF01121.20 GAK68211.1 - 2.1e-51 174.1 0.0 2.9e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase MFS_1 PF07690.16 GAK68212.1 - 7.2e-33 114.0 42.2 7.2e-33 114.0 42.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily CDH-cyt PF16010.5 GAK68213.1 - 5e-12 45.9 7.8 1.1e-11 44.8 7.8 1.6 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 GAK68213.1 - 2.5e-09 37.4 7.7 5.2e-09 36.4 7.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 GAK68213.1 - 5.3e-06 26.2 3.7 5.3e-06 26.2 3.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 GAK68213.1 - 7.9e-06 26.1 1.3 1.6e-05 25.1 1.3 1.6 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 GAK68213.1 - 4.9e-05 23.5 7.7 9.7e-05 22.6 5.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) TctB PF07331.11 GAK68213.1 - 1.2 9.5 13.3 4.8 7.4 3.4 2.4 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF973 PF06157.11 GAK68213.1 - 1.7 7.6 7.2 2.8 6.9 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF420 PF04238.12 GAK68213.1 - 2.8 8.2 7.9 15 5.9 7.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF420) AAA_2 PF07724.14 GAK68214.1 - 1.3e-46 158.8 0.0 5.1e-45 153.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAK68214.1 - 9.7e-33 112.2 1.6 9.7e-33 112.2 1.6 3.1 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 GAK68214.1 - 7.1e-26 91.2 0.0 8.1e-16 58.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAK68214.1 - 7.6e-19 67.6 0.1 4e-18 65.3 0.1 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAK68214.1 - 6.9e-14 52.0 0.0 2.3e-08 34.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 GAK68214.1 - 4.3e-12 46.0 14.0 1.1e-06 28.7 0.3 4.4 5 0 0 5 5 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 GAK68214.1 - 2.9e-10 40.8 10.5 2e-05 25.1 0.1 5.6 4 2 1 6 6 6 2 AAA ATPase domain Sigma54_activat PF00158.26 GAK68214.1 - 2e-09 37.4 0.0 1.7e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 GAK68214.1 - 1e-06 29.1 0.3 0.047 14.0 0.0 4.5 2 2 0 2 2 2 1 AAA domain TniB PF05621.11 GAK68214.1 - 1.7e-06 27.6 0.0 0.004 16.6 0.0 3.4 3 0 0 3 3 3 1 Bacterial TniB protein Zeta_toxin PF06414.12 GAK68214.1 - 4.2e-06 26.2 0.0 0.0032 16.8 0.0 3.1 3 0 0 3 3 2 1 Zeta toxin AAA_33 PF13671.6 GAK68214.1 - 0.0001 22.5 0.1 0.85 9.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 GAK68214.1 - 0.00011 21.7 0.2 0.61 9.4 0.1 3.5 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAK68214.1 - 0.00044 19.8 0.0 1.3 8.5 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region TsaE PF02367.17 GAK68214.1 - 0.0012 18.8 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAK68214.1 - 0.0016 18.2 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 GAK68214.1 - 0.0024 17.6 0.0 5.5 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAK68214.1 - 0.0025 17.8 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.11 GAK68214.1 - 0.0026 17.9 0.0 0.0073 16.4 0.0 1.7 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.22 GAK68214.1 - 0.0027 18.1 0.1 6.1 7.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase RuvB_N PF05496.12 GAK68214.1 - 0.0029 17.4 0.0 5.5 6.7 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 GAK68214.1 - 0.0038 17.6 0.0 0.13 12.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAK68214.1 - 0.0056 16.6 0.0 1.4 8.8 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 GAK68214.1 - 0.0071 16.3 1.7 0.7 9.8 0.0 4.1 4 0 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAK68214.1 - 0.0074 16.8 1.3 4.7 7.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 GAK68214.1 - 0.0092 14.9 0.0 4.7 6.0 0.0 3.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 GAK68214.1 - 0.012 15.9 0.0 2.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 GAK68214.1 - 0.012 15.9 5.2 0.47 10.7 0.0 3.9 3 1 0 3 3 2 0 AAA domain AAA_29 PF13555.6 GAK68214.1 - 0.013 15.2 0.1 8.6 6.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 GAK68214.1 - 0.019 14.1 0.0 0.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 GAK68214.1 - 0.023 14.3 0.1 6.8 6.2 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAK68214.1 - 0.045 14.3 0.7 16 6.0 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_3 PF07726.11 GAK68214.1 - 0.064 13.1 0.0 10 6.0 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 GAK68214.1 - 0.074 13.1 0.0 3.7 7.6 0.0 3.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Oxidored_molyb PF00174.19 GAK68214.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Spc7 PF08317.11 GAK68214.1 - 0.13 11.1 9.1 0.24 10.3 9.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4085 PF13315.6 GAK68214.1 - 0.15 11.7 0.7 11 5.6 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF4085) AAA_25 PF13481.6 GAK68214.1 - 0.29 10.7 3.3 2.7 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain EMP24_GP25L PF01105.24 GAK68214.1 - 0.97 9.4 3.4 0.52 10.2 0.8 1.9 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD DUF724 PF05266.14 GAK68214.1 - 1.5 8.6 4.7 3.8 7.3 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF16 PF01519.16 GAK68214.1 - 5.1 7.6 8.0 4.9 7.7 2.5 3.4 3 1 0 3 3 1 0 Protein of unknown function DUF16 MoCF_biosynth PF00994.24 GAK68215.1 - 1.1e-32 112.7 0.0 1.6e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 GAK68215.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain His_Phos_2 PF00328.22 GAK68216.1 - 5.4e-30 105.0 0.0 1.4e-29 103.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Kinesin PF00225.23 GAK68217.1 - 8.8e-55 185.9 0.0 2e-54 184.7 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAK68217.1 - 2.4e-07 30.8 0.0 4.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 GAK68217.1 - 0.015 15.7 1.6 0.015 15.7 1.6 2.8 2 2 0 2 2 2 0 AAA ATPase domain Glyco_hydro_3_C PF01915.22 GAK68218.1 - 1.4e-36 126.4 0.1 2.6e-36 125.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAK68218.1 - 1.2e-29 103.7 0.0 1.9e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAK68218.1 - 3.2e-12 46.4 0.0 7.2e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.10 GAK68218.1 - 0.16 11.0 0.9 0.34 9.9 0.9 1.5 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain CARDB PF07705.11 GAK68218.1 - 0.28 11.5 1.5 0.88 9.9 0.1 2.6 3 1 0 3 3 3 0 CARDB Acyltransferase PF01553.21 GAK68219.1 - 3.6e-33 114.0 0.0 5.5e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Claudin_2 PF13903.6 GAK68219.1 - 3 7.5 5.5 5.7 6.7 5.5 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction BTB PF00651.31 GAK68220.1 - 2.6e-09 37.3 0.0 2.4e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Aldedh PF00171.22 GAK68221.1 - 2.6e-74 250.4 0.0 3.5e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF677 PF05055.12 GAK68221.1 - 0.077 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) MukB_hinge PF16330.5 GAK68221.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 MukB hinge domain Zn_clus PF00172.18 GAK68223.1 - 0.012 15.7 2.2 0.012 15.7 2.2 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arm-DNA-bind_2 PF12167.8 GAK68223.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Arm DNA-binding domain ABC_membrane PF00664.23 GAK68224.1 - 8e-44 150.3 21.6 5.3e-27 95.2 8.4 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAK68224.1 - 1.6e-36 125.8 0.0 1.3e-20 74.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAK68224.1 - 2.6e-10 40.1 0.0 0.0013 18.3 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK68224.1 - 0.00032 20.4 3.0 0.032 14.0 0.3 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAK68224.1 - 0.00069 19.9 0.2 2.3 8.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAK68224.1 - 0.001 18.9 0.5 0.12 12.1 0.1 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 GAK68224.1 - 0.0012 17.8 0.1 0.0023 16.9 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAK68224.1 - 0.0015 19.0 4.1 0.036 14.4 0.3 3.8 3 1 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 GAK68224.1 - 0.0038 16.3 0.2 0.19 10.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 GAK68224.1 - 0.013 15.7 0.4 0.013 15.7 0.4 1.7 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_25 PF13481.6 GAK68224.1 - 0.02 14.5 1.8 5.2 6.6 0.1 3.2 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 GAK68224.1 - 0.025 14.7 1.2 0.054 13.6 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 GAK68224.1 - 0.048 13.9 0.2 6.4 7.1 0.1 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 GAK68224.1 - 0.055 13.6 0.6 5.7 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GAK68224.1 - 0.064 12.9 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 GAK68224.1 - 0.064 12.8 2.5 6.7 6.3 0.9 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAK68224.1 - 0.07 13.0 0.9 6.2 6.7 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 GAK68224.1 - 0.083 12.4 0.1 9.5 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 GAK68224.1 - 0.11 11.9 3.0 0.93 8.8 0.5 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 GAK68224.1 - 0.12 11.2 0.9 0.98 8.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 GAK68224.1 - 0.13 12.7 4.1 0.5 10.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain Orthoreo_P10 PF07204.11 GAK68224.1 - 0.14 12.2 0.8 3.5 7.7 0.0 3.1 3 0 0 3 3 2 0 Orthoreovirus membrane fusion protein p10 Dynamin_N PF00350.23 GAK68224.1 - 0.14 12.2 1.4 17 5.4 0.3 2.5 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 GAK68224.1 - 0.18 11.5 0.9 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 GAK68224.1 - 0.24 11.3 0.9 13 5.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 GAK68224.1 - 0.31 10.5 2.4 13 5.1 0.3 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.6 GAK68224.1 - 0.7 10.4 3.1 3.2 8.3 0.2 2.7 2 0 0 2 2 2 0 AAA domain DUF2613 PF11021.8 GAK68224.1 - 6.6 6.9 7.0 29 4.9 3.0 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF2370 PF10176.9 GAK68225.1 - 6.4e-75 251.7 0.0 2.1e-74 250.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) TMEM252 PF15664.5 GAK68225.1 - 0.49 10.1 0.0 0.49 10.1 0.0 2.8 4 0 0 4 4 4 0 Transmembrane protein 252 family SPX PF03105.19 GAK68225.1 - 1.1 9.1 6.0 35 4.1 5.9 2.3 2 0 0 2 2 2 0 SPX domain RINT1_TIP1 PF04437.13 GAK68226.1 - 2.4e-79 267.5 0.0 5.1e-79 266.5 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CP12 PF02672.15 GAK68226.1 - 0.061 14.1 0.2 0.34 11.7 0.2 2.4 1 0 0 1 1 1 0 CP12 domain Cytochrom_B562 PF07361.11 GAK68226.1 - 0.3 11.8 3.9 0.67 10.6 0.1 2.9 3 0 0 3 3 3 0 Cytochrome b562 MWFE PF15879.5 GAK68227.1 - 2.9e-22 78.6 0.5 3.5e-22 78.3 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ANAPC4_WD40 PF12894.7 GAK68228.1 - 5.1e-07 29.9 0.0 0.00092 19.5 0.0 3.6 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAK68228.1 - 4.8e-05 23.7 1.7 14 6.3 0.1 4.4 4 0 0 4 4 4 2 PQQ-like domain PQQ_2 PF13360.6 GAK68228.1 - 7.8e-05 22.4 0.9 0.023 14.3 0.1 2.4 2 1 0 2 2 2 2 PQQ-like domain WD40 PF00400.32 GAK68228.1 - 0.00022 21.9 9.3 0.16 12.9 0.2 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.12 GAK68228.1 - 0.82 9.4 24.7 0.55 9.9 0.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SH3_9 PF14604.6 GAK68229.1 - 4e-14 52.2 0.2 7.4e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAK68229.1 - 3.5e-13 48.9 0.5 7e-13 48.0 0.5 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 GAK68229.1 - 2e-12 47.6 0.0 3.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 GAK68229.1 - 1e-10 41.1 0.1 2.2e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 GAK68229.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAK68229.1 - 0.0002 21.7 0.0 0.00041 20.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 GAK68229.1 - 0.012 15.9 0.3 0.021 15.1 0.3 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif MCM3AP_GANP PF16769.5 GAK68229.1 - 8.3 4.5 6.1 13 3.9 6.1 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP UPF0160 PF03690.13 GAK68230.1 - 4.5e-130 433.9 0.0 8e-130 433.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) cobW PF02492.19 GAK68230.1 - 2.5e-32 111.9 0.0 4.2e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SNARE_assoc PF09335.11 GAK68230.1 - 2.5e-14 53.8 4.4 5.2e-14 52.8 4.4 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein AAA_16 PF13191.6 GAK68230.1 - 0.011 16.1 0.2 0.084 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 GAK68230.1 - 0.059 13.9 0.1 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAK68230.1 - 0.18 10.8 2.0 1.1 8.2 2.0 2.0 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pox_A32 PF04665.12 GAK68230.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein FSH1 PF03959.13 GAK68231.1 - 1.1e-18 67.7 0.0 3e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 GAK68232.1 - 1.1e-47 162.8 0.0 5.1e-47 160.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAK68232.1 - 7.9e-36 124.2 0.0 1.4e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAK68232.1 - 5.3e-30 103.9 1.1 1.2e-29 102.7 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 GAK68232.1 - 1.5e-18 67.8 0.9 1.4e-17 64.6 0.1 2.8 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 GAK68232.1 - 3.5e-18 65.9 0.1 7.7e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 GAK68232.1 - 0.00017 21.4 1.7 0.007 16.1 0.1 3.2 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 GAK68232.1 - 0.094 12.1 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Sod_Fe_C PF02777.18 GAK68233.1 - 5.7e-21 74.6 0.1 1.8e-09 37.7 0.1 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Ndc1_Nup PF09531.10 GAK68234.1 - 6.8e-69 233.1 7.4 8.8e-69 232.8 7.4 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup zf-C3HC4 PF00097.25 GAK68235.1 - 1.1e-05 25.2 4.6 1.1e-05 25.2 4.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAK68235.1 - 7.1e-05 22.8 7.3 7.1e-05 22.8 7.3 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAK68235.1 - 0.00024 20.9 6.7 0.00024 20.9 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK68235.1 - 0.00031 20.6 6.9 0.00031 20.6 6.9 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAK68235.1 - 0.0013 19.1 11.3 0.0013 19.1 11.3 2.8 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 GAK68235.1 - 0.074 13.3 10.8 0.04 14.2 5.0 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 GAK68235.1 - 3.6 7.3 11.7 0.25 11.0 5.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAK68235.1 - 5.9 6.8 15.6 0.18 11.7 7.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2613 PF11021.8 GAK68236.1 - 1.5 9.0 5.9 0.49 10.5 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) NIF PF03031.18 GAK68237.1 - 1.7e-12 47.4 0.0 6.9e-05 22.7 0.0 3.3 1 1 0 2 2 2 2 NLI interacting factor-like phosphatase CLTH PF10607.9 GAK68238.1 - 1.2e-20 73.9 0.0 2.3e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAK68238.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 LisH WD40 PF00400.32 GAK68239.1 - 4.1e-26 90.7 11.1 7.4e-06 26.6 0.9 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68239.1 - 0.0061 16.8 0.1 23 5.4 0.0 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAK68239.1 - 0.018 14.0 0.1 2.9 6.8 0.0 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAK68239.1 - 0.037 13.3 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Autophagy_act_C PF03987.15 GAK68241.1 - 8.1e-08 32.7 0.2 1.7e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Fer4_24 PF18109.1 GAK68241.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain ANAPC4_WD40 PF12894.7 GAK68242.1 - 5.2e-06 26.7 0.0 0.2 12.0 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAK68242.1 - 0.00023 21.9 1.3 0.32 11.9 0.0 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat Hira PF07569.11 GAK68242.1 - 0.11 12.2 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split RF-1 PF00472.20 GAK68243.1 - 1.8e-22 79.4 1.6 2.5e-22 79.0 1.6 1.1 1 0 0 1 1 1 1 RF-1 domain WD40 PF00400.32 GAK68244.1 - 0.12 13.3 22.5 4.9 8.2 0.4 5.7 6 1 0 6 6 6 0 WD domain, G-beta repeat DNApol_Exo PF18136.1 GAK68245.1 - 4e-87 291.9 0.0 3.7e-78 262.5 0.0 2.5 2 0 0 2 2 2 2 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 GAK68245.1 - 1.1e-48 166.2 0.0 2.1e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Rhabdo_M1 PF03342.13 GAK68246.1 - 0.0069 15.8 5.7 0.011 15.1 5.7 1.2 1 0 0 1 1 1 1 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) APG6_N PF17675.1 GAK68246.1 - 4.5 7.8 22.1 7 7.2 22.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Neur_chan_memb PF02932.16 GAK68246.1 - 6.8 6.7 7.5 9.8 6.2 7.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Halogen_Hydrol PF10112.9 GAK68246.1 - 8.5 6.3 8.7 0.49 10.4 0.1 2.1 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Sdh_cyt PF01127.22 GAK68247.1 - 8.9e-24 83.8 3.8 1.2e-23 83.4 3.8 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M16_C PF05193.21 GAK68248.1 - 2.5e-17 63.5 0.0 1.3e-13 51.4 0.0 3.4 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAK68248.1 - 2.4e-06 27.6 0.0 8.1e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AF-4 PF05110.13 GAK68248.1 - 0.031 12.4 1.3 0.046 11.8 1.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Serglycin PF04360.12 GAK68248.1 - 1.9 8.4 4.8 4.3 7.3 4.8 1.5 1 0 0 1 1 1 0 Serglycin COX17 PF05051.13 GAK68249.1 - 1.1e-19 70.5 6.9 1.6e-19 69.9 6.9 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 GAK68249.1 - 0.0013 18.9 2.3 0.0019 18.4 2.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) TP_methylase PF00590.20 GAK68250.1 - 1.5e-33 116.5 0.2 3.3e-33 115.4 0.2 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 GAK68250.1 - 6.4e-12 45.8 0.6 1.2e-10 41.8 0.6 2.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 GAK68250.1 - 1.1e-09 37.8 1.1 1.2e-06 28.0 0.3 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 GAK68250.1 - 1.3e-09 37.4 0.2 2.6e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SOBP PF15279.6 GAK68250.1 - 0.4 11.3 6.3 0.73 10.4 6.3 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Abhydrolase_3 PF07859.13 GAK68253.1 - 9.7e-18 64.8 0.2 8.8e-16 58.4 0.2 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAK68253.1 - 3.8e-10 39.2 0.0 2.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAK68253.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3605 PF12239.8 GAK68254.1 - 2.4e-22 79.9 0.0 8.6e-14 52.1 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3605) GMC_oxred_N PF00732.19 GAK68255.1 - 3.5e-57 194.0 0.0 4.5e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK68255.1 - 1.8e-29 103.1 0.3 4.9e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAK68255.1 - 1.7e-05 24.9 0.8 0.00012 22.3 1.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAK68255.1 - 2.2e-05 23.7 0.2 0.00018 20.7 1.1 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAK68255.1 - 0.00035 19.7 0.1 0.00054 19.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAK68255.1 - 0.00091 18.5 0.4 0.0017 17.7 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAK68255.1 - 0.0031 16.8 2.5 0.0073 15.6 1.6 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAK68255.1 - 0.0042 16.4 1.7 0.078 12.2 1.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAK68255.1 - 0.009 15.6 3.1 0.013 15.1 3.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAK68255.1 - 0.075 11.7 0.4 0.17 10.5 0.4 1.6 1 0 0 1 1 1 0 HI0933-like protein Solute_trans_a PF03619.16 GAK68256.1 - 3.5e-83 279.2 26.5 4.5e-83 278.8 26.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4288 PF14119.6 GAK68256.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) DPM3 PF08285.11 GAK68256.1 - 1.6 8.9 9.8 0.047 13.9 2.0 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1713 PF08213.11 GAK68257.1 - 1.8e-09 37.3 24.3 1.8e-09 37.3 24.3 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) TIP49 PF06068.13 GAK68258.1 - 1.7e-159 530.7 0.2 2.2e-159 530.3 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAK68258.1 - 4.7e-24 84.3 1.1 2.9e-23 81.8 1.0 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 GAK68258.1 - 6.6e-08 33.1 1.4 3.2e-05 24.4 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAK68258.1 - 1e-06 28.6 0.3 0.0013 18.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 GAK68258.1 - 1.2e-06 28.1 0.8 1.2e-06 28.1 0.8 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 GAK68258.1 - 0.00047 19.6 1.5 0.0099 15.3 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAK68258.1 - 0.0019 18.6 0.1 0.0072 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAK68258.1 - 0.0026 17.8 0.7 1.3 9.0 0.0 3.3 3 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 GAK68258.1 - 0.0031 17.9 2.5 0.014 15.7 0.5 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAK68258.1 - 0.017 15.4 0.1 0.77 10.0 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAK68258.1 - 0.019 14.5 1.6 0.041 13.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAK68258.1 - 0.048 13.9 0.1 0.16 12.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 GAK68258.1 - 0.049 13.8 0.2 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAK68258.1 - 0.075 12.7 0.1 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain COG4 PF08318.12 GAK68259.1 - 1.2e-102 343.5 0.0 2e-102 342.7 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein Sec7_N PF12783.7 GAK68259.1 - 0.0097 15.8 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HIP1_clath_bdg PF16515.5 GAK68259.1 - 0.011 16.3 2.7 0.051 14.2 2.7 2.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 GAK68259.1 - 0.38 9.6 2.2 0.8 8.5 2.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Nuf2 PF03800.14 GAK68260.1 - 1.2e-36 125.8 0.0 1.2e-36 125.8 0.0 2.8 2 1 1 3 3 3 1 Nuf2 family DHR10 PF18595.1 GAK68260.1 - 0.00017 21.6 15.5 0.00017 21.6 15.5 4.0 2 2 2 4 4 4 1 Designed helical repeat protein 10 domain GM_CSF PF01109.17 GAK68260.1 - 0.0028 17.8 1.2 0.0028 17.8 1.2 2.9 2 1 1 3 3 3 1 Granulocyte-macrophage colony-stimulating factor Adhesin_P1_N PF18652.1 GAK68260.1 - 0.61 10.1 0.0 0.61 10.1 0.0 3.6 4 1 0 4 4 4 0 Adhesin P1 N-terminal domain ATP-synt_G PF04718.15 GAK68260.1 - 1.1 10.1 9.4 0.19 12.6 0.4 3.7 2 1 2 4 4 4 0 Mitochondrial ATP synthase g subunit THOC7 PF05615.13 GAK68260.1 - 1.4 9.2 44.3 0.061 13.6 8.5 3.6 2 1 2 4 4 4 0 Tho complex subunit 7 Baculo_PEP_C PF04513.12 GAK68260.1 - 1.6 8.8 19.3 0.73 9.9 3.1 3.9 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 GAK68260.1 - 4.2 7.4 32.0 3 7.9 6.9 4.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 GAK68260.1 - 6.3 5.6 54.2 2.9 6.7 15.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 GAK68260.1 - 6.6 7.0 43.9 0.78 10.0 11.6 4.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Phage_int_SAM_6 PF18644.1 GAK68260.1 - 6.8 6.7 11.6 0.41 10.7 0.7 3.4 1 1 1 3 3 3 0 Phage integrase SAM-like domain Methyltransf_16 PF10294.9 GAK68261.1 - 2.9e-18 66.2 0.0 4.1e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 GAK68261.1 - 4.4e-05 23.4 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK68261.1 - 0.01 16.5 0.0 0.027 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAK68261.1 - 0.013 16.1 0.0 0.034 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GAK68261.1 - 0.061 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 GAK68261.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 GAK68261.1 - 0.16 12.7 0.1 1.6 9.5 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain UPF0146 PF03686.13 GAK68261.1 - 0.16 11.8 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) DUF1869 PF08956.10 GAK68261.1 - 0.18 11.7 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) FAM35_C PF15793.5 GAK68262.1 - 0.026 13.9 0.2 0.041 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein family FAM35, C-terminal Glutaredoxin PF00462.24 GAK68264.1 - 5.4e-19 68.2 0.0 3.7e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 GAK68264.1 - 1.4e-13 50.7 0.0 2.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAK68264.1 - 0.0059 17.0 0.0 0.36 11.3 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 GAK68264.1 - 0.0078 16.2 0.1 0.069 13.2 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.11 GAK68264.1 - 0.0082 16.1 0.0 0.12 12.3 0.0 2.4 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 GAK68264.1 - 0.0095 16.2 0.1 0.32 11.4 0.0 2.6 2 1 0 3 3 3 1 Thioredoxin-like SH3BGR PF04908.15 GAK68264.1 - 0.031 14.4 0.0 0.088 13.0 0.0 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 GAK68264.1 - 0.17 12.3 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RabGAP-TBC PF00566.18 GAK68265.1 - 2.2e-45 154.9 0.0 3.1e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TatD_DNase PF01026.21 GAK68266.1 - 2.8e-06 26.9 0.0 2.8e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase LETM1 PF07766.13 GAK68267.1 - 1.1e-101 339.7 2.6 1.1e-101 339.7 2.6 2.4 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 GAK68267.1 - 4.8e-07 30.1 6.3 7.8e-07 29.5 0.2 3.7 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 GAK68267.1 - 6.2e-05 22.8 0.2 0.00021 21.1 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair DUF1682 PF07946.14 GAK68267.1 - 0.0013 18.0 10.9 0.0026 17.0 10.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) EF-hand_1 PF00036.32 GAK68267.1 - 0.0017 17.8 0.8 1 9.0 0.0 3.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 GAK68267.1 - 0.0017 18.1 0.2 4.8 7.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain RPA_C PF08784.11 GAK68267.1 - 0.013 16.1 0.4 0.069 13.8 0.4 2.2 1 0 0 1 1 1 0 Replication protein A C terminal TIR_2 PF13676.6 GAK68267.1 - 0.046 14.3 0.0 0.24 12.0 0.0 2.3 2 0 0 2 2 2 0 TIR domain WD40 PF00400.32 GAK68268.1 - 2.7e-12 47.0 10.1 0.15 13.0 0.0 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68268.1 - 0.019 15.3 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain tRNA_synthFbeta PF17759.1 GAK68269.1 - 7.4e-47 159.6 0.0 1.1e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 GAK68269.1 - 1.4e-33 114.9 0.0 2.5e-32 110.9 0.0 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GAK68269.1 - 4.1e-26 91.7 0.1 6.8e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GAK68269.1 - 5.4e-20 71.4 0.0 7.3e-18 64.6 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 GAK68269.1 - 0.069 12.6 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) EST1_DNA_bind PF10373.9 GAK68270.1 - 9.4e-29 100.8 0.0 4.8e-26 91.9 0.0 2.9 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 GAK68270.1 - 4.7e-21 75.8 0.0 1.7e-20 74.0 0.0 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 Piwi PF02171.17 GAK68271.1 - 7.7e-78 261.8 0.0 1e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 GAK68271.1 - 1.8e-11 43.5 0.0 4.8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 GAK68271.1 - 2.1e-11 43.8 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 GAK68271.1 - 4.3e-10 40.4 0.0 9.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 GAK68271.1 - 1e-09 38.5 0.0 3e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 GAK68271.1 - 1.7e-06 28.2 0.0 4.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute DUF2461 PF09365.10 GAK68272.1 - 5.6e-27 95.0 0.3 8.1e-27 94.5 0.3 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) IFT57 PF10498.9 GAK68272.1 - 0.11 11.5 1.5 0.12 11.3 1.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BUD22 PF09073.10 GAK68272.1 - 0.43 9.9 13.9 0.49 9.7 13.9 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAK68272.1 - 0.56 8.4 10.1 0.64 8.2 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAK68272.1 - 1.8 6.7 8.6 2 6.5 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4661 PF15576.6 GAK68272.1 - 5.4 6.9 8.1 6.5 6.6 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PAPS_reduct PF01507.19 GAK68274.1 - 7.5e-21 74.9 0.2 6.3e-15 55.6 0.0 3.0 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family PRP3 PF08572.10 GAK68275.1 - 4.3e-65 219.6 0.4 1e-64 218.3 0.4 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 GAK68275.1 - 1.9e-37 128.6 0.0 3.5e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Phage_Nu1 PF07471.12 GAK68275.1 - 2.1 8.1 6.3 0.13 12.0 0.4 1.9 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 GREB1 PF15782.5 GAK68275.1 - 4.6 4.2 4.9 6.5 3.7 4.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-RING_2 PF13639.6 GAK68277.1 - 5.5e-12 45.8 7.7 1.1e-11 44.8 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAK68277.1 - 2.7e-11 43.6 6.5 7.4e-11 42.2 6.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAK68277.1 - 4.2e-08 32.9 8.5 9e-08 31.8 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAK68277.1 - 1.1e-07 31.6 7.5 2.3e-07 30.6 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAK68277.1 - 3.6e-07 30.1 3.4 8.5e-07 29.0 3.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAK68277.1 - 4.7e-06 26.5 3.5 1.3e-05 25.1 3.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAK68277.1 - 3.4e-05 23.6 4.0 6.4e-05 22.7 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAK68277.1 - 7.6e-05 22.6 5.7 0.00015 21.7 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAK68277.1 - 0.00075 19.2 5.9 0.0015 18.3 5.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAK68277.1 - 0.029 14.0 5.6 0.068 12.8 5.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_5 PF17121.5 GAK68277.1 - 0.063 13.2 4.5 0.2 11.6 4.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAK68277.1 - 0.066 13.3 6.3 0.17 12.0 6.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 GAK68277.1 - 0.087 12.6 4.5 0.23 11.3 4.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 GAK68277.1 - 0.097 12.9 5.0 0.1 12.8 3.2 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 GAK68277.1 - 0.13 12.2 6.0 0.25 11.2 6.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 GAK68277.1 - 0.3 11.3 4.2 0.62 10.3 4.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAK68277.1 - 0.44 10.5 9.2 13 5.7 9.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 GAK68277.1 - 0.57 10.5 7.2 1.4 9.3 7.2 1.7 1 0 0 1 1 1 0 RING-like domain zinc_ribbon_16 PF17034.5 GAK68277.1 - 1.4 9.1 7.4 1.4 9.1 5.7 1.8 1 1 0 1 1 1 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 GAK68277.1 - 4.6 7.4 8.0 2.1 8.5 3.5 2.4 2 0 0 2 2 2 0 Zinc-finger Fes1 PF08609.10 GAK68278.1 - 1.2e-23 83.8 1.5 3.2e-23 82.4 0.5 2.4 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 GAK68278.1 - 0.00022 21.2 0.1 6.2 7.4 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 GAK68278.1 - 0.00032 21.0 0.2 0.0016 18.8 0.2 2.3 2 1 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 GAK68278.1 - 0.00092 19.7 1.0 0.0059 17.1 0.1 3.0 2 1 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.20 GAK68278.1 - 0.0085 14.7 0.1 0.042 12.4 0.1 2.0 1 1 1 2 2 2 1 Adaptin N terminal region Arm PF00514.23 GAK68278.1 - 0.022 14.8 0.0 3 8.0 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 GAK68278.1 - 0.053 13.6 0.1 0.44 10.7 0.0 2.1 1 1 1 2 2 2 0 V-ATPase subunit H DUF3361 PF11841.8 GAK68278.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) DUF448 PF04296.13 GAK68279.1 - 0.0054 16.6 0.4 0.071 13.0 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF448) SurA_N_3 PF13624.6 GAK68279.1 - 0.08 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 SurA N-terminal domain Cpn60_TCP1 PF00118.24 GAK68280.1 - 1.4e-155 518.7 1.9 1.6e-155 518.5 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans PF04082.18 GAK68281.1 - 6.5e-26 90.9 0.0 1.4e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAK68281.1 - 2.9e-08 33.7 12.7 4.7e-08 33.0 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.21 GAK68282.1 - 1.6e-119 398.8 0.6 2.5e-119 398.1 0.6 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAK68282.1 - 4.8e-42 143.6 0.1 1.3e-41 142.3 0.1 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAK68282.1 - 4.9e-08 32.9 0.0 2.9e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAK68282.1 - 7.2e-05 22.1 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 GAK68282.1 - 0.00016 20.7 0.1 0.00027 20.0 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAK68282.1 - 0.0057 16.5 0.8 0.029 14.1 0.8 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HPTransfase PF10090.9 GAK68282.1 - 0.061 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain DUF2280 PF10045.9 GAK68282.1 - 0.2 11.9 0.7 0.44 10.9 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) adh_short_C2 PF13561.6 GAK68283.1 - 1.7e-53 181.6 1.2 2.4e-53 181.1 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAK68283.1 - 4.7e-42 143.7 1.2 6.7e-42 143.2 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAK68283.1 - 4.9e-14 52.7 1.2 7e-14 52.1 1.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAK68283.1 - 0.00073 19.0 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAK68283.1 - 0.0013 18.3 0.9 0.0043 16.5 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK68283.1 - 0.0016 17.5 0.0 0.0041 16.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.27 GAK68283.1 - 0.047 14.3 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cu-oxidase PF00394.22 GAK68284.1 - 1.9e-32 112.6 0.2 5.1e-30 104.7 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAK68284.1 - 2.2e-32 111.7 7.5 2.9e-30 104.8 2.8 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAK68284.1 - 1.6e-31 108.8 4.7 5.1e-19 68.4 0.1 3.8 3 1 1 4 4 4 3 Multicopper oxidase Phosphoesterase PF04185.14 GAK68286.1 - 1.6e-77 261.1 2.2 2.5e-77 260.5 2.2 1.2 1 0 0 1 1 1 1 Phosphoesterase family FliC PF12445.8 GAK68286.1 - 0.0015 18.9 0.8 0.0044 17.4 0.8 1.7 1 0 0 1 1 1 1 Flagellin protein DAO PF01266.24 GAK68287.1 - 1.4e-34 120.2 4.6 1.7e-34 120.0 4.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK68287.1 - 1e-05 24.9 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 GAK68287.1 - 0.00091 19.5 0.2 0.0025 18.1 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 GAK68287.1 - 0.0037 17.5 0.2 0.0087 16.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAK68287.1 - 0.022 14.7 3.0 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.21 GAK68287.1 - 0.025 13.9 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 GAK68287.1 - 0.047 13.3 0.1 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 GAK68287.1 - 0.23 10.5 0.6 3.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.25 GAK68288.1 - 8.9e-45 152.5 1.3 2.8e-23 82.4 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAK68288.1 - 8.2e-38 130.3 0.1 1e-18 67.7 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK68288.1 - 1.3e-05 25.2 0.3 3.4e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 KR domain Spt20 PF12090.8 GAK68289.1 - 1.2e-33 116.7 0.0 1.3e-20 74.0 0.0 6.2 5 1 0 5 5 5 2 Spt20 family Utp14 PF04615.13 GAK68289.1 - 0.29 9.7 46.4 0.56 8.7 46.4 1.5 1 0 0 1 1 1 0 Utp14 protein PPP4R2 PF09184.11 GAK68289.1 - 5.6 6.5 20.5 0.0092 15.6 9.6 1.9 3 0 0 3 3 3 0 PPP4R2 NDK PF00334.19 GAK68290.1 - 3.7e-33 114.4 0.0 4.9e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Cnd2 PF05786.14 GAK68291.1 - 1.7e-163 546.2 0.0 1.7e-163 546.2 0.0 2.3 1 1 1 2 2 2 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GAK68291.1 - 0.014 15.6 0.0 0.042 14.1 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Vfa1 PF08432.10 GAK68291.1 - 4.6 7.5 13.8 22 5.3 0.4 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF2462 PF09495.10 GAK68292.1 - 1.2e-19 70.7 14.3 1.2e-19 70.7 14.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Y_phosphatase2 PF03162.13 GAK68293.1 - 3.8e-58 195.7 0.0 6.5e-58 195.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAK68293.1 - 2.3e-07 31.0 0.0 4.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAK68293.1 - 0.00064 19.5 0.0 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAK68293.1 - 0.00076 19.1 0.0 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PolyA_pol PF01743.20 GAK68294.1 - 1.1e-21 77.6 0.0 2.8e-21 76.2 0.0 1.7 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAK68294.1 - 0.00018 21.2 0.1 0.00044 20.0 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A SRP19 PF01922.17 GAK68295.1 - 7.3e-25 87.7 0.0 1.7e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein Pkinase PF00069.25 GAK68296.1 - 2.2e-65 220.6 0.0 2.9e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68296.1 - 1.8e-33 115.9 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK68296.1 - 1.4e-09 37.7 0.0 2.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAK68296.1 - 0.00098 19.1 0.6 0.0024 17.8 0.6 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAK68296.1 - 0.0011 18.4 0.1 0.0021 17.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAK68296.1 - 0.0023 16.8 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAK68296.1 - 0.0044 16.0 0.1 0.0063 15.5 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Histidinol_dh PF00815.20 GAK68297.1 - 1.4e-156 521.6 1.2 1.4e-156 521.6 1.2 1.7 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 GAK68297.1 - 1.7e-22 79.0 0.2 3e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GAK68297.1 - 1.7e-14 54.0 0.2 5.2e-14 52.4 0.2 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 GAK68297.1 - 0.011 15.9 0.4 0.023 14.9 0.1 1.7 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Peptidase_S10 PF00450.22 GAK68298.1 - 7.1e-93 312.3 0.0 1.8e-92 311.0 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase CRAL_TRIO PF00650.20 GAK68299.1 - 8.6e-34 116.5 0.0 1.3e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAK68299.1 - 8.4e-16 57.9 0.4 1.7e-15 56.9 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NPBW PF15180.6 GAK68299.1 - 0.08 12.8 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Neuropeptides B and W AhpC-TSA_2 PF13911.6 GAK68300.1 - 5.8e-13 49.0 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 GAK68300.1 - 1.8e-07 31.0 0.0 4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAK68300.1 - 3.7e-07 30.1 0.0 8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Asp PF00026.23 GAK68302.1 - 1.2e-106 356.8 0.1 1.4e-106 356.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAK68302.1 - 3.5e-13 50.2 1.5 2.9e-11 43.9 1.5 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAK68302.1 - 0.00065 20.3 0.1 0.28 11.8 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 GAK68302.1 - 0.006 16.4 0.0 0.038 13.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 GAK68302.1 - 0.0088 16.6 0.0 2.9 8.5 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Pkinase PF00069.25 GAK68303.1 - 5.2e-73 245.6 0.0 6.6e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68303.1 - 1.1e-35 123.2 0.0 1.6e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK68303.1 - 2.5e-05 23.7 0.1 0.00012 21.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAK68303.1 - 0.00047 19.2 0.1 0.072 12.0 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 GAK68303.1 - 0.01 15.2 0.6 0.027 13.8 0.6 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Complex1_49kDa PF00346.19 GAK68304.1 - 1.5e-121 404.7 0.0 1.9e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 GAK68304.1 - 0.0031 16.5 0.0 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Na_Ca_ex PF01699.24 GAK68305.1 - 6.4e-47 159.3 38.9 4.9e-27 94.7 12.5 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3169 PF11368.8 GAK68305.1 - 0.13 11.8 2.1 9.3 5.7 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) MFS_1 PF07690.16 GAK68306.1 - 1.3e-29 103.3 32.6 1.3e-29 103.3 32.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pinin_SDK_memA PF04696.13 GAK68306.1 - 0.088 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Zn_clus PF00172.18 GAK68308.1 - 1.1e-06 28.7 8.3 2e-06 27.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAK68308.1 - 0.0024 17.0 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3535 PF12054.8 GAK68310.1 - 4.2e-79 266.8 0.0 2.5e-75 254.4 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3535) HEAT PF02985.22 GAK68310.1 - 5.7e-10 38.6 9.8 0.2 12.0 0.1 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 GAK68310.1 - 0.0022 18.3 13.9 1.9 8.9 0.1 5.8 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 GAK68310.1 - 0.0085 16.6 6.9 68 4.1 0.0 6.9 7 0 0 7 7 7 0 HEAT-like repeat TAF6_C PF07571.13 GAK68310.1 - 0.026 14.8 0.0 11 6.4 0.0 4.7 6 0 0 6 6 6 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 GAK68310.1 - 0.11 13.1 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region BLM10_mid PF16507.5 GAK68310.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region Ipi1_N PF12333.8 GAK68310.1 - 0.12 13.0 0.1 1.2 9.7 0.0 2.6 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.7 GAK68310.1 - 0.21 11.6 0.7 1.9 8.5 0.3 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ribosomal_L27A PF00828.19 GAK68311.1 - 1.4e-34 119.5 0.0 1.9e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MerR_1 PF13411.6 GAK68311.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein Utp21 PF04192.12 GAK68312.1 - 1.8e-50 171.6 0.3 4.1e-50 170.5 0.0 1.7 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 GAK68312.1 - 3.8e-10 40.2 8.8 0.21 12.5 0.0 7.8 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68312.1 - 8.9e-09 35.5 0.0 0.08 13.3 0.0 6.3 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAK68312.1 - 0.00015 21.4 0.6 0.018 14.7 0.1 2.6 2 0 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.16 GAK68312.1 - 0.058 11.9 0.5 0.39 9.2 0.3 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain RhlB PF12300.8 GAK68312.1 - 2.4 8.3 9.2 6.8 6.8 9.2 1.8 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB DEAD PF00270.29 GAK68313.1 - 2.4e-45 154.5 0.0 4.3e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK68313.1 - 5.4e-23 81.4 0.0 3e-22 79.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAK68313.1 - 1.5e-18 66.8 0.4 1.5e-18 66.8 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAK68313.1 - 0.0027 17.7 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Hist_deacetyl PF00850.19 GAK68314.1 - 3.9e-72 243.3 0.0 4.9e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Zn_clus PF00172.18 GAK68315.1 - 1e-05 25.5 10.2 1.8e-05 24.7 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.12 GAK68315.1 - 0.0024 17.4 24.3 0.0033 16.9 24.3 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GAK68315.1 - 0.0056 15.0 18.8 0.0075 14.6 18.8 1.2 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 GAK68315.1 - 0.0066 15.0 15.8 0.01 14.3 15.8 1.3 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 GAK68315.1 - 0.012 13.9 23.9 0.017 13.4 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 GAK68315.1 - 0.053 11.6 12.2 0.085 10.9 12.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 GAK68315.1 - 0.94 7.5 32.5 1.4 7.0 32.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi LAP1C PF05609.12 GAK68315.1 - 2.7 7.0 14.9 3.6 6.6 14.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) WW PF00397.26 GAK68316.1 - 1.1e-08 34.9 2.8 2e-08 34.1 2.8 1.4 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 GAK68316.1 - 0.0055 16.8 17.4 0.0055 16.8 17.4 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Trnau1ap PF17654.1 GAK68316.1 - 8.9 7.2 11.6 5.8 7.8 1.2 2.4 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins ETC_C1_NDUFA5 PF04716.14 GAK68317.1 - 4.2e-19 68.1 5.6 9e-19 67.0 5.6 1.6 1 1 0 1 1 1 1 ETC complex I subunit conserved region DUF1115 PF06544.12 GAK68318.1 - 0.00034 20.7 0.1 0.0034 17.5 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) Sel1 PF08238.12 GAK68319.1 - 1.3e-43 146.5 17.5 7.3e-08 32.8 0.1 8.0 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.6 GAK68319.1 - 0.26 11.0 4.1 0.55 10.0 0.0 3.6 3 0 0 3 3 3 0 TPR repeat DAO PF01266.24 GAK68320.1 - 1.5e-34 120.1 0.6 2.3e-34 119.5 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK68320.1 - 7.5e-11 41.7 4.6 1.4e-06 27.7 0.2 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 GAK68320.1 - 3.4e-09 36.3 0.3 1.4e-07 31.1 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK68320.1 - 7.2e-06 24.9 0.1 0.019 13.7 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 GAK68320.1 - 8.1e-06 26.0 0.5 3.7e-05 23.9 0.1 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAK68320.1 - 3e-05 23.3 0.1 0.078 12.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAK68320.1 - 0.00011 21.5 0.0 0.003 16.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GAK68320.1 - 0.00019 21.5 1.6 0.1 12.6 0.1 2.5 1 1 0 2 2 2 2 FAD-NAD(P)-binding 3HCDH_N PF02737.18 GAK68320.1 - 0.00041 20.3 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAK68320.1 - 0.00045 20.7 0.0 0.27 11.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAK68320.1 - 0.0015 17.9 0.1 0.0097 15.2 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 GAK68320.1 - 0.019 13.8 0.4 0.063 12.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 GAK68320.1 - 0.021 14.1 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.15 GAK68320.1 - 0.061 13.5 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.12 GAK68320.1 - 0.066 12.2 0.2 0.52 9.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 GAK68320.1 - 0.087 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 GAK68320.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HA2 PF04408.23 GAK68321.1 - 1.6e-24 86.3 0.1 1.6e-24 86.3 0.1 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAK68321.1 - 6.4e-21 74.5 0.0 1.5e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAK68321.1 - 2.2e-14 53.7 0.0 5.1e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 GAK68321.1 - 1.1e-07 32.0 0.2 2.9e-07 30.7 0.2 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 GAK68321.1 - 1.7e-05 24.6 0.1 3.7e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAK68321.1 - 4.4e-05 23.3 0.2 0.00098 18.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAK68321.1 - 0.00043 20.6 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAK68321.1 - 0.0013 17.9 0.6 0.0035 16.4 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 GAK68321.1 - 0.0043 17.6 0.1 1.5 9.4 0.0 3.4 2 1 1 3 3 3 1 ABC transporter AAA_19 PF13245.6 GAK68321.1 - 0.0047 17.3 0.2 0.015 15.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain Microtub_bd PF16796.5 GAK68321.1 - 0.0075 16.2 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Flavi_DEAD PF07652.14 GAK68321.1 - 0.042 13.8 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 GAK68321.1 - 0.047 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 GAK68321.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 GAK68321.1 - 0.13 12.3 0.0 0.83 9.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATP11 PF06644.11 GAK68321.1 - 2.4 7.9 4.9 13 5.4 0.0 3.0 3 0 0 3 3 3 0 ATP11 protein DAGAT PF03982.13 GAK68322.1 - 3.8e-105 351.0 0.0 4.7e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CS PF04969.16 GAK68323.1 - 3.7e-05 24.6 0.0 6.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 CS domain Sporozoite_P67 PF05642.11 GAK68323.1 - 0.0044 15.2 0.8 0.0049 15.0 0.8 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Porin_4 PF13609.6 GAK68324.1 - 0.46 10.2 6.2 0.4 10.4 6.2 1.1 1 0 0 1 1 1 0 Gram-negative porin K_channel_TID PF07941.11 GAK68324.1 - 2.9 8.4 12.1 4.3 7.9 12.1 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain MFS_1 PF07690.16 GAK68325.1 - 2e-45 155.3 46.7 2.9e-43 148.2 49.2 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAK68325.1 - 3.4e-21 75.3 33.8 7.6e-21 74.2 33.6 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAK68325.1 - 9e-11 41.3 31.6 1.2e-10 40.9 10.1 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter DUF3530 PF12048.8 GAK68325.1 - 0.0024 17.3 0.2 0.0024 17.3 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3530) DUF1180 PF06679.12 GAK68325.1 - 0.0025 18.2 2.6 0.0072 16.8 2.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) FAM176 PF14851.6 GAK68325.1 - 0.0064 16.1 1.3 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 FAM176 family DUF5337 PF17272.2 GAK68325.1 - 0.016 15.0 3.7 0.12 12.2 3.7 2.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) NDUF_B12 PF08122.12 GAK68325.1 - 2.1 8.5 11.7 0.87 9.7 0.1 4.7 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase B12 subunit family XPG_N PF00752.17 GAK68327.1 - 2.3e-29 101.8 0.0 4.7e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAK68327.1 - 9.5e-26 90.0 0.0 3.2e-25 88.3 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 GAK68327.1 - 0.00024 20.7 0.0 0.00076 19.0 0.0 1.9 1 1 0 1 1 1 1 XPG domain containing Y_phosphatase2 PF03162.13 GAK68328.1 - 3.3e-49 166.6 0.0 3.8e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAK68328.1 - 0.0002 21.4 0.0 0.00099 19.1 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAK68328.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAK68328.1 - 0.051 13.1 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.13 GAK68328.1 - 0.21 11.7 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Voltage_CLC PF00654.20 GAK68329.1 - 3.6e-91 306.1 26.4 3.6e-91 306.1 26.4 1.8 3 0 0 3 3 3 1 Voltage gated chloride channel DASH_Hsk3 PF08227.11 GAK68329.1 - 2.5e-11 43.7 1.2 2.5e-11 43.7 1.2 2.5 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like CBS PF00571.28 GAK68329.1 - 0.18 12.2 0.0 0.72 10.3 0.0 2.0 2 0 0 2 2 2 0 CBS domain Ribophorin_II PF05817.14 GAK68329.1 - 3.3 6.2 3.9 5.3 5.5 3.9 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Alk_phosphatase PF00245.20 GAK68330.1 - 5.6e-91 305.5 0.1 7.1e-91 305.2 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase TFA2_Winged_2 PF18121.1 GAK68330.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 HMGL-like PF00682.19 GAK68331.1 - 1.5e-80 270.6 0.8 2.3e-80 269.9 0.8 1.3 1 0 0 1 1 1 1 HMGL-like OTU PF02338.19 GAK68332.1 - 1.5e-22 80.5 0.0 2.5e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease T2SSM PF04612.12 GAK68332.1 - 0.013 15.5 0.2 0.22 11.6 0.9 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Peptidase_C65 PF10275.9 GAK68332.1 - 0.021 14.3 0.0 1.2 8.6 0.0 2.7 2 1 0 2 2 2 0 Peptidase C65 Otubain Zip PF02535.22 GAK68332.1 - 0.37 10.0 0.7 0.52 9.5 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_20 PF14561.6 GAK68332.1 - 0.52 10.7 5.9 0.55 10.6 0.9 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Inv-AAD PF18785.1 GAK68333.1 - 5.5e-28 97.4 0.0 2.3e-23 82.5 0.0 2.2 2 0 0 2 2 2 2 Invertebrate-AID/APOBEC-deaminase PAP2 PF01569.21 GAK68333.1 - 7e-12 45.3 5.5 5.7e-11 42.3 5.5 2.1 1 1 0 1 1 1 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.23 GAK68333.1 - 9.7e-11 41.5 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 GAK68333.1 - 0.0042 17.2 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 UbiA PF01040.18 GAK68333.1 - 0.0091 15.3 1.3 0.0091 15.3 1.3 1.8 2 1 0 2 2 2 1 UbiA prenyltransferase family APOBEC_N PF08210.11 GAK68333.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF212 PF02681.14 GAK68333.1 - 0.09 12.9 0.1 8 6.6 0.0 2.5 2 0 0 2 2 2 0 Divergent PAP2 family EamA PF00892.20 GAK68334.1 - 3.8e-21 75.7 29.3 2.8e-11 43.7 4.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family Trp_oprn_chp PF09534.10 GAK68334.1 - 0.85 9.4 9.1 3.9 7.2 0.2 2.9 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RseC_MucC PF04246.12 GAK68334.1 - 4.6 7.2 10.6 17 5.4 0.4 3.4 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DNA_methylase PF00145.17 GAK68335.1 - 3.9e-12 46.2 0.0 9.3e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase SHQ1 PF04925.15 GAK68336.1 - 3.4e-28 98.4 0.0 4.6e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 SHQ1 protein TilS PF09179.11 GAK68336.1 - 0.036 14.6 1.7 0.24 11.9 1.3 2.5 2 0 0 2 2 2 0 TilS substrate binding domain Glyco_hydro_46 PF01374.18 GAK68336.1 - 0.037 13.6 0.3 0.066 12.8 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 WAPL PF07814.13 GAK68337.1 - 4.3e-09 35.6 0.3 1.5e-07 30.6 0.0 2.4 2 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin BIR PF00653.21 GAK68338.1 - 1.7e-29 102.3 0.3 5.4e-23 81.4 0.6 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Meth_synt_2 PF01717.18 GAK68339.1 - 6.1e-18 65.2 0.0 9.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAK68339.1 - 0.011 15.2 0.1 0.4 10.2 0.0 2.7 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain adh_short PF00106.25 GAK68340.1 - 1.7e-38 132.1 0.1 3.3e-38 131.1 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK68340.1 - 1.9e-37 129.1 0.6 1.7e-36 126.0 0.6 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK68340.1 - 3.2e-08 33.7 1.6 1.4e-07 31.6 0.1 2.2 2 0 0 2 2 2 1 KR domain Baculo_p47 PF05112.12 GAK68340.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Baculovirus P47 protein Glyco_hydro_39 PF01229.17 GAK68341.1 - 5.9e-05 21.8 0.0 9.3e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Astacin PF01400.24 GAK68342.1 - 1.2e-09 38.1 0.2 2.4e-09 37.1 0.2 1.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 GAK68342.1 - 1.3e-06 28.4 0.1 0.043 13.6 0.0 2.3 2 0 0 2 2 2 2 Matrixin Peptidase_M43 PF05572.13 GAK68342.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Alginate_lyase PF05426.12 GAK68343.1 - 4.9e-09 36.1 0.0 1.2e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Alginate lyase DUF4267 PF14087.6 GAK68343.1 - 0.0057 16.7 1.2 0.012 15.7 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) RTA1 PF04479.13 GAK68344.1 - 5.3e-43 147.0 9.9 5.3e-43 147.0 9.9 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF4345 PF14248.6 GAK68345.1 - 1e-20 73.8 10.0 1.3e-20 73.5 10.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF2065 PF09838.9 GAK68345.1 - 0.12 12.4 3.8 1.1 9.3 3.7 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) PIRT PF15099.6 GAK68345.1 - 0.14 11.7 0.1 0.25 10.9 0.0 1.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Ribosomal_L23 PF00276.20 GAK68346.1 - 5.5e-06 26.7 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 SKI PF01202.22 GAK68347.1 - 9.8e-12 45.3 0.0 7.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.6 GAK68347.1 - 4.1e-07 30.2 0.2 1.2e-05 25.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAK68347.1 - 2.6e-06 28.0 0.2 0.00018 22.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAK68347.1 - 0.00055 20.2 0.8 0.056 13.7 0.4 2.7 1 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 GAK68347.1 - 0.0017 18.5 0.0 0.01 16.0 0.0 2.1 2 1 0 2 2 2 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 GAK68347.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_16 PF13191.6 GAK68347.1 - 0.0078 16.6 0.2 0.014 15.8 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 GAK68347.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 GAK68347.1 - 0.01 16.3 0.2 0.065 13.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 GAK68347.1 - 0.014 15.2 0.1 6.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Herpes_Helicase PF02689.14 GAK68347.1 - 0.027 12.4 0.0 0.076 10.9 0.0 1.7 2 0 0 2 2 2 0 Helicase DUF2075 PF09848.9 GAK68347.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 GAK68347.1 - 0.029 13.6 1.1 0.063 12.5 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin ABC_tran PF00005.27 GAK68347.1 - 0.041 14.4 0.1 0.071 13.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter CoaE PF01121.20 GAK68347.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_29 PF13555.6 GAK68347.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAK68347.1 - 0.1 13.1 0.2 0.28 11.6 0.1 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAK68347.1 - 0.23 11.0 2.8 0.27 10.8 0.5 2.2 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 GAK68347.1 - 0.37 10.9 3.6 0.47 10.5 1.3 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NIF PF03031.18 GAK68349.1 - 1.9e-50 170.6 0.0 3.1e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec1 PF00995.23 GAK68350.1 - 5.6e-123 412.2 0.0 7.8e-123 411.7 0.0 1.2 1 0 0 1 1 1 1 Sec1 family DUF1045 PF06299.12 GAK68350.1 - 0.027 14.5 0.4 0.065 13.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) PMEI PF04043.15 GAK68350.1 - 0.16 12.3 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor PAT1 PF09770.9 GAK68351.1 - 2.6e-38 131.9 17.6 5.8e-38 130.8 17.6 1.6 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spore_YhcN_YlaJ PF09580.10 GAK68351.1 - 0.48 10.5 6.1 1.3 9.1 6.1 1.7 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3381 PF11861.8 GAK68351.1 - 2.1 8.1 7.9 24 4.7 4.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) GTP_EFTU PF00009.27 GAK68352.1 - 1.3e-22 80.3 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAK68352.1 - 3.7e-12 46.5 0.0 7.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAK68352.1 - 2.8e-07 30.8 0.2 1.2e-06 28.7 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAK68352.1 - 0.18 11.7 4.2 0.099 12.6 1.3 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 HhH-GPD PF00730.25 GAK68353.1 - 4.2e-19 69.0 0.0 1.1e-18 67.7 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAK68353.1 - 1.1e-08 34.5 0.0 4.4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GAK68353.1 - 0.089 13.4 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain OMPdecase PF00215.24 GAK68354.1 - 4.5e-75 252.1 0.0 5.6e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mit_ribos_Mrp51 PF11709.8 GAK68355.1 - 1.1e-12 48.2 1.4 4.7e-12 46.2 1.4 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Cyclin PF08613.11 GAK68356.1 - 1.9e-07 31.6 0.3 6.6e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin zinc_ribbon_15 PF17032.5 GAK68359.1 - 3.4e-06 27.7 0.5 3.4e-06 27.7 0.5 1.6 2 0 0 2 2 2 1 zinc-ribbon family zf-NADH-PPase PF09297.11 GAK68359.1 - 0.023 14.4 0.7 0.023 14.4 0.7 1.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 GAK68359.1 - 0.25 11.3 5.7 1.3 9.1 5.7 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RecR PF02132.15 GAK68359.1 - 0.32 10.6 2.3 13 5.4 0.2 2.2 2 0 0 2 2 2 0 RecR protein CM_2 PF01817.21 GAK68360.1 - 0.04 14.3 0.2 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 Chorismate mutase type II NIF PF03031.18 GAK68361.1 - 1e-21 77.3 0.0 1.4e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 GAK68361.1 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CO_deh_flav_C PF03450.17 GAK68361.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 1 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Kinesin PF00225.23 GAK68363.1 - 1.1e-112 376.3 0.0 1.1e-112 376.3 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAK68363.1 - 1.9e-28 99.3 0.0 8.4e-28 97.2 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding YqeY PF09424.10 GAK68363.1 - 9.7e-14 51.7 4.2 9.7e-14 51.7 4.2 3.6 4 0 0 4 4 4 1 Yqey-like protein DUF465 PF04325.13 GAK68363.1 - 1.1e-08 34.9 3.9 1.1e-08 34.9 3.9 3.8 3 1 1 4 4 4 1 Protein of unknown function (DUF465) ATG16 PF08614.11 GAK68363.1 - 0.0033 17.7 17.3 0.0033 17.7 17.3 6.6 3 2 1 5 5 5 2 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 GAK68363.1 - 0.005 16.6 10.7 0.005 16.6 10.7 6.5 5 3 2 7 7 7 2 Domain of unknown function (DUF4201) Sox_N PF12444.8 GAK68363.1 - 0.2 12.8 2.6 2 9.6 0.0 4.1 3 0 0 3 3 3 0 Sox developmental protein N terminal GTP_EFTU PF00009.27 GAK68364.1 - 5.8e-22 78.2 0.0 1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 GAK68364.1 - 2.6e-11 43.6 3.5 5.3e-11 42.7 3.5 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 GAK68364.1 - 7.9e-05 22.7 0.0 0.002 18.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1296 PF06972.11 GAK68364.1 - 0.0015 18.6 0.1 0.0032 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) DUF4202 PF13875.6 GAK68365.1 - 1.7e-63 213.9 0.2 3.8e-63 212.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_23 PF13489.6 GAK68365.1 - 8.6e-16 58.2 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF1754 PF08555.10 GAK68365.1 - 1e-15 58.3 11.6 1e-15 58.3 11.6 2.5 3 0 0 3 3 3 1 Eukaryotic family of unknown function (DUF1754) Methyltransf_12 PF08242.12 GAK68365.1 - 1.4e-14 54.6 0.0 8.8e-14 52.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK68365.1 - 7.9e-14 52.1 0.0 2.6e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK68365.1 - 1.9e-10 41.3 0.0 5.6e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAK68365.1 - 3.6e-09 36.6 0.0 7.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAK68365.1 - 4.2e-05 24.5 0.0 0.00022 22.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAK68365.1 - 0.00088 18.9 0.1 0.0025 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain ADK PF00406.22 GAK68366.1 - 3.5e-47 160.3 0.0 4.8e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAK68366.1 - 1.9e-36 125.5 0.0 3.2e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAK68366.1 - 2e-09 38.1 0.0 3.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAK68366.1 - 6.2e-05 23.2 0.0 0.00022 21.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAK68366.1 - 8.7e-05 22.3 0.1 0.44 10.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 GAK68366.1 - 0.056 12.7 0.1 0.22 10.8 0.1 2.1 1 1 0 1 1 1 0 Zeta toxin Dynamitin PF04912.14 GAK68367.1 - 2e-76 257.8 17.3 4.3e-76 256.8 17.3 1.5 1 1 0 1 1 1 1 Dynamitin Jnk-SapK_ap_N PF09744.9 GAK68367.1 - 0.012 15.9 3.6 0.012 15.9 3.6 2.9 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 Sugarporin_N PF11471.8 GAK68367.1 - 0.023 14.6 2.5 1.6 8.7 0.1 3.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Fib_alpha PF08702.10 GAK68367.1 - 0.045 13.9 1.9 0.092 12.9 0.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 GAK68367.1 - 0.23 11.5 1.7 0.54 10.3 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4726 PF15855.5 GAK68367.1 - 0.33 11.2 0.1 0.33 11.2 0.1 4.2 5 1 0 5 5 5 0 Domain of unknown function (DUF4726) Nsp1_C PF05064.13 GAK68367.1 - 0.91 9.3 4.9 0.44 10.4 1.5 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region Baculo_PEP_C PF04513.12 GAK68367.1 - 1 9.4 6.7 1.2 9.2 1.2 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 GAK68367.1 - 1.2 9.6 8.3 0.28 11.6 2.9 2.8 3 0 0 3 3 2 0 Snapin/Pallidin Matrilin_ccoil PF10393.9 GAK68367.1 - 2.7 7.9 8.0 2.9 7.8 0.1 3.8 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin FlgN PF05130.12 GAK68367.1 - 5.8 7.4 21.2 1.1 9.8 0.5 3.7 1 1 3 4 4 4 0 FlgN protein ZapB PF06005.12 GAK68367.1 - 5.9 7.4 17.5 2.2 8.8 1.9 4.2 3 3 1 4 4 4 0 Cell division protein ZapB V-SNARE PF05008.15 GAK68367.1 - 6.2 7.3 13.9 1.8 9.0 3.6 4.0 3 2 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Transp_cyt_pur PF02133.15 GAK68368.1 - 1.9e-31 109.3 26.6 3.5e-31 108.5 26.6 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OST3_OST6 PF04756.13 GAK68369.1 - 2.4e-89 299.5 3.0 3e-89 299.2 3.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 GAK68369.1 - 9.2e-05 22.4 0.1 0.0002 21.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin DUF3112 PF11309.8 GAK68369.1 - 0.057 12.9 0.8 0.15 11.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DSBA PF01323.20 GAK68369.1 - 0.27 11.0 1.8 0.85 9.4 0.2 2.4 3 0 0 3 3 3 0 DSBA-like thioredoxin domain HlyIII PF03006.20 GAK68369.1 - 0.35 10.6 5.9 1.1 8.9 0.5 2.5 2 1 0 2 2 2 0 Haemolysin-III related DUF2157 PF09925.9 GAK68369.1 - 0.81 9.5 7.9 1.4 8.7 1.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF3784 PF12650.7 GAK68369.1 - 0.87 9.8 5.6 9.9 6.4 2.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) WD40 PF00400.32 GAK68370.1 - 4.5e-38 128.6 24.5 5e-06 27.1 0.1 8.4 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68370.1 - 6.8e-12 45.5 2.3 0.12 12.7 0.0 6.9 2 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAK68370.1 - 3.9e-05 22.5 3.8 0.43 9.2 0.1 4.2 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAK68370.1 - 0.026 13.5 0.1 0.66 8.9 0.0 2.5 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cse1 PF08506.10 GAK68371.1 - 4.7e-135 450.2 0.3 3.4e-133 444.0 0.4 2.2 2 0 0 2 2 2 2 Cse1 CAS_CSE1 PF03378.15 GAK68371.1 - 8.7e-121 403.5 0.0 1.7e-120 402.6 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 GAK68371.1 - 1.3e-12 47.4 1.0 3.6e-11 42.8 0.6 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAK68371.1 - 0.00033 20.7 0.5 0.0071 16.4 0.0 3.6 3 0 0 3 3 3 1 Exportin 1-like protein Nop PF01798.18 GAK68371.1 - 0.02 14.4 0.2 0.069 12.6 0.1 1.9 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin HEAT PF02985.22 GAK68371.1 - 0.031 14.5 0.6 9.2 6.8 0.2 4.1 3 0 0 3 3 3 0 HEAT repeat NDUFA12 PF05071.16 GAK68372.1 - 1.1e-08 35.8 0.1 2.7e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF3365 PF11845.8 GAK68372.1 - 0.26 11.6 1.8 0.48 10.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Cucumo_2B PF03263.13 GAK68372.1 - 0.26 11.7 4.5 0.16 12.5 0.6 2.2 2 0 0 2 2 2 0 Cucumovirus protein 2B TPR_1 PF00515.28 GAK68373.1 - 4.5e-08 32.6 6.6 0.018 14.8 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAK68373.1 - 6.4e-07 29.0 6.8 0.004 17.2 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK68373.1 - 2e-05 25.0 15.2 0.00083 19.8 2.9 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAK68373.1 - 7.1e-05 23.3 9.4 0.063 14.1 0.2 3.6 2 2 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK68373.1 - 0.0048 17.1 6.7 0.15 12.3 3.9 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAK68373.1 - 0.0066 16.6 0.2 0.51 10.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAK68373.1 - 0.045 14.4 2.4 0.045 14.4 2.4 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAK68373.1 - 0.063 13.3 7.3 0.075 13.1 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAK68373.1 - 0.15 12.4 8.7 0.83 10.0 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF5484 PF17583.2 GAK68373.1 - 0.22 11.2 0.1 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5484) THOC7 PF05615.13 GAK68373.1 - 0.37 11.1 2.6 0.59 10.4 2.6 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 TPR_6 PF13174.6 GAK68373.1 - 9 7.2 7.3 65 4.5 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Surfac_D-trimer PF09006.11 GAK68374.1 - 0.17 11.8 0.9 4.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF836 PF05768.14 GAK68375.1 - 9.3e-12 45.2 0.1 1.2e-11 44.9 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.21 GAK68375.1 - 0.006 16.5 0.0 0.0076 16.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Robl_LC7 PF03259.17 GAK68376.1 - 0.00024 20.8 0.0 0.00056 19.6 0.0 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain DLIC PF05783.11 GAK68376.1 - 0.02 13.8 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) LAMTOR5 PF16672.5 GAK68376.1 - 0.035 14.0 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Zn_clus PF00172.18 GAK68377.1 - 0.023 14.8 10.8 0.26 11.5 10.8 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 GAK68378.1 - 1.1e-58 198.8 1.0 9.4e-58 195.8 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 GAK68378.1 - 1.2e-21 76.8 4.5 9.4e-11 41.9 0.7 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site SAT PF16073.5 GAK68378.1 - 2.9e-21 76.3 0.2 7.5e-21 75.0 0.2 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 GAK68378.1 - 4.6e-17 62.9 1.0 6.5e-16 59.1 0.1 2.9 3 0 0 3 3 3 1 Thioesterase domain Ketoacyl-synt_C PF02801.22 GAK68378.1 - 1.8e-13 50.6 0.6 6e-13 48.9 0.6 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAK68378.1 - 0.00081 19.8 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Helicase_C PF00271.31 GAK68379.1 - 1.8e-17 63.7 0.0 4.5e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 GAK68379.1 - 1.6e-15 57.3 2.7 2.8e-15 56.5 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAK68379.1 - 6.2e-10 39.3 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAK68379.1 - 7.7e-10 38.8 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAK68379.1 - 9.5e-05 22.7 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAK68379.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 GAK68379.1 - 0.039 13.0 0.3 0.29 10.2 0.1 2.5 2 1 1 3 3 3 0 Type II/IV secretion system protein DUF494 PF04361.13 GAK68379.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF494) ResIII PF04851.15 GAK68379.1 - 0.075 13.0 0.0 0.41 10.6 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 GAK68379.1 - 0.1 12.0 0.2 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Astacin PF01400.24 GAK68380.1 - 4e-08 33.1 0.0 1e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 GAK68380.1 - 0.025 14.4 2.7 0.17 11.7 2.7 2.1 1 1 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 GAK68380.1 - 0.044 13.9 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 GAK68380.1 - 0.094 12.6 0.1 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A WW PF00397.26 GAK68381.1 - 4.4e-10 39.5 0.3 1e-09 38.3 0.3 1.7 1 0 0 1 1 1 1 WW domain CPSF_A PF03178.15 GAK68382.1 - 3e-56 191.1 0.0 8.8e-56 189.6 0.0 1.8 1 1 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 GAK68382.1 - 7.5e-07 28.1 0.0 3.7e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_S26e PF01283.19 GAK68383.1 - 1.8e-48 163.4 4.7 3.1e-48 162.7 4.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S26e LRR_6 PF13516.6 GAK68385.1 - 1.3e-05 24.9 5.4 14 6.1 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 GAK68385.1 - 0.0017 18.1 0.2 0.36 10.6 0.0 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAK68385.1 - 0.0027 18.1 0.1 4.4 7.9 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) SPX PF03105.19 GAK68385.1 - 4.5 7.1 12.0 8.8 6.1 12.0 1.4 1 0 0 1 1 1 0 SPX domain AMP-binding PF00501.28 GAK68386.1 - 1.2e-70 238.2 0.0 1.7e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAK68386.1 - 4.6e-59 199.7 0.0 6.6e-56 189.3 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 GAK68386.1 - 2.4e-49 167.5 2.4 3.6e-49 166.9 1.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAK68386.1 - 4.4e-37 127.9 0.9 6.4e-36 124.1 1.4 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAK68386.1 - 1.9e-21 76.8 1.1 9.4e-18 64.7 0.9 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAK68386.1 - 2e-19 70.0 0.3 1.4e-10 41.1 0.0 3.3 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAK68386.1 - 7.5e-10 38.3 0.0 6.6e-05 22.1 0.0 3.1 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 GAK68386.1 - 9.8e-08 32.2 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 GAK68386.1 - 7.1e-07 28.6 1.8 4.5e-05 22.7 0.2 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAK68386.1 - 5.3e-06 26.0 0.0 0.0048 16.3 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAK68386.1 - 6.3e-05 22.2 0.2 0.008 15.3 0.0 3.0 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAK68386.1 - 7.1e-05 22.8 4.3 0.0038 17.1 3.0 3.7 3 1 0 3 3 3 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 GAK68386.1 - 0.0016 17.7 0.1 0.0052 16.1 0.1 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AMP-binding_C PF13193.6 GAK68386.1 - 0.0055 17.7 0.3 0.036 15.0 0.1 2.7 3 0 0 3 3 1 1 AMP-binding enzyme C-terminal domain DFP PF04127.15 GAK68386.1 - 0.077 12.8 4.0 1.2 8.9 4.0 2.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HRXXH PF13933.6 GAK68387.1 - 2.3e-27 96.2 0.6 2.3e-27 96.2 0.6 1.6 2 0 0 2 2 2 1 Putative peptidase family MCR_beta_N PF02783.15 GAK68387.1 - 0.17 11.5 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain FH2 PF02181.23 GAK68388.1 - 3.2e-65 220.7 13.5 4.4e-65 220.2 5.7 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 GAK68388.1 - 7.1e-44 149.8 0.0 5.9e-43 146.8 0.0 2.4 1 1 1 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAK68388.1 - 9.4e-44 149.2 0.1 1e-42 145.8 0.0 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain CorA PF01544.18 GAK68388.1 - 0.14 11.4 12.7 0.36 10.1 0.5 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CorA PF01544.18 GAK68389.1 - 2.8e-11 43.3 0.3 4.1e-11 42.8 0.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UreD PF01774.17 GAK68390.1 - 8.3e-69 231.7 0.1 1.2e-68 231.2 0.1 1.2 1 0 0 1 1 1 1 UreD urease accessory protein EI24 PF07264.11 GAK68390.1 - 6.2e-07 29.8 0.4 1.2e-06 28.9 0.4 1.5 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) UcrQ PF02939.16 GAK68391.1 - 2.2e-32 110.8 1.8 2.7e-32 110.5 1.8 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 GAK68391.1 - 0.0019 18.6 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Fe-ADH PF00465.19 GAK68392.1 - 1.7e-68 231.1 0.1 2.3e-68 230.7 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAK68392.1 - 6.7e-15 55.5 0.0 1.4e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Transposase_24 PF03004.14 GAK68392.1 - 0.02 15.0 0.4 0.13 12.3 0.5 1.9 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) AAA_16 PF13191.6 GAK68392.1 - 0.025 15.0 0.2 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain LAGLIDADG_3 PF14528.6 GAK68392.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 LAGLIDADG-like domain zinc_ribbon_10 PF10058.9 GAK68393.1 - 3.1e-21 74.9 0.2 4.7e-21 74.3 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 GAK68393.1 - 0.0058 16.0 0.7 0.023 14.2 0.1 2.2 2 0 0 2 2 2 1 Mu-like prophage protein Com Zn_ribbon_SprT PF17283.2 GAK68393.1 - 0.99 9.4 3.6 2.5 8.1 0.9 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain LIM PF00412.22 GAK68394.1 - 8.6e-28 96.3 34.1 1.2e-12 47.9 2.5 5.1 4 1 0 4 4 4 4 LIM domain TFIIA PF03153.13 GAK68394.1 - 1.2 9.0 13.5 1.8 8.5 13.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_2 PF00152.20 GAK68395.1 - 4.1e-86 288.9 0.0 1.6e-45 155.6 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAK68395.1 - 8.7e-06 25.6 0.0 2.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAK68395.1 - 0.041 13.4 0.0 1.6 8.2 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) SNF5 PF04855.12 GAK68396.1 - 4.2e-66 223.1 1.6 1.1e-59 202.2 0.5 2.1 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 SBDS PF01172.18 GAK68397.1 - 2.6e-16 59.5 0.0 3.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Swi6_N PF18530.1 GAK68397.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Swi6 N-terminal domain TFIIA PF03153.13 GAK68399.1 - 2.4 8.1 13.9 0.16 11.9 8.5 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Clp1 PF06807.14 GAK68401.1 - 3.2e-29 101.7 0.0 5.9e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_P PF16575.5 GAK68401.1 - 3.3e-23 82.4 0.0 1e-17 64.6 0.0 3.8 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 GAK68401.1 - 9.1e-23 80.3 0.0 1.5e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor ZapB PF06005.12 GAK68401.1 - 0.012 16.0 0.9 0.031 14.7 0.9 1.7 1 0 0 1 1 1 0 Cell division protein ZapB AAA_28 PF13521.6 GAK68401.1 - 0.094 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAK68401.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 GAK68401.1 - 0.14 12.2 0.1 8.1 6.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TOM13 PF08219.11 GAK68403.1 - 1.3e-09 37.9 1.3 2.5e-09 37.0 1.3 1.6 1 1 0 1 1 1 1 Outer membrane protein TOM13 E1-E2_ATPase PF00122.20 GAK68404.1 - 2e-25 89.3 0.0 2e-25 89.3 0.0 3.4 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 GAK68404.1 - 3.9e-13 50.2 0.6 3.8e-05 24.1 0.0 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAK68404.1 - 5.7e-08 32.7 0.0 1.8e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) P5-ATPase PF12409.8 GAK68404.1 - 1.9e-07 31.2 0.0 4.4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 GAK68404.1 - 4.5e-05 23.0 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Docking PF08990.11 GAK68405.1 - 0.076 12.7 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking DUF1712 PF08217.11 GAK68406.1 - 3.8e-08 32.3 0.0 5.7e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Coatomer_WDAD PF04053.14 GAK68407.1 - 2e-137 458.9 0.0 3.5e-137 458.1 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 GAK68407.1 - 1.1e-98 330.6 0.0 1.4e-98 330.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 GAK68407.1 - 2.5e-43 145.2 13.1 4.1e-08 33.8 0.4 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68407.1 - 9.6e-14 51.5 0.3 0.0027 18.0 0.0 6.5 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 GAK68407.1 - 0.023 14.6 0.2 0.12 12.2 0.0 2.2 3 0 0 3 3 3 0 Region in Clathrin and VPS Nucleoporin_N PF08801.11 GAK68407.1 - 0.065 12.0 0.2 0.66 8.6 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 GAK68407.1 - 0.51 8.9 6.5 1.7 7.2 0.0 3.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 p31comet PF06581.12 GAK68408.1 - 0.00023 20.4 0.6 0.028 13.6 0.3 3.1 3 0 0 3 3 3 2 Mad1 and Cdc20-bound-Mad2 binding E1-E2_ATPase PF00122.20 GAK68409.1 - 2.8e-43 147.5 1.0 2.8e-43 147.5 1.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAK68409.1 - 1.7e-40 138.6 2.5 1.7e-40 138.6 2.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAK68409.1 - 5.7e-20 72.5 0.1 3.7e-08 33.9 0.0 3.8 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAK68409.1 - 2.1e-14 53.3 0.0 4.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAK68409.1 - 4.4e-12 45.5 0.6 8.5e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAK68409.1 - 0.00087 19.1 0.5 0.0016 18.2 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF805 PF05656.14 GAK68409.1 - 0.013 15.9 3.2 0.13 12.7 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) SUR7 PF06687.12 GAK68409.1 - 0.014 15.0 0.5 0.014 15.0 0.5 2.8 3 1 0 3 3 3 0 SUR7/PalI family DUF2207 PF09972.9 GAK68409.1 - 0.036 12.8 2.9 2.6 6.7 0.1 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) COX15-CtaA PF02628.15 GAK68409.1 - 0.051 12.6 1.4 0.53 9.3 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein Peptidase_C32 PF05411.12 GAK68409.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DUF4181 PF13789.6 GAK68409.1 - 0.86 9.9 6.5 1.4 9.2 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF2231 PF09990.9 GAK68409.1 - 7.8 7.0 7.5 0.85 10.1 0.5 3.0 3 0 0 3 3 2 0 Predicted membrane protein (DUF2231) Glyco_hydro_79C PF16862.5 GAK68410.1 - 8.6e-20 71.6 4.2 6.5e-19 68.7 1.4 2.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Orthoreo_P10 PF07204.11 GAK68410.1 - 0.0063 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Herpes_gE PF02480.16 GAK68410.1 - 0.0064 15.3 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.6 GAK68410.1 - 0.022 15.0 7.6 0.67 10.2 7.6 2.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 GAK68410.1 - 0.18 12.7 0.0 0.38 11.7 0.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Arginase PF00491.21 GAK68411.1 - 4.1e-79 266.0 0.1 4.9e-79 265.7 0.1 1.0 1 0 0 1 1 1 1 Arginase family DEAD PF00270.29 GAK68412.1 - 7e-37 126.9 0.1 1.8e-36 125.6 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAK68412.1 - 1.8e-28 99.1 0.0 7.8e-26 90.6 0.1 2.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAK68412.1 - 2.2e-08 34.3 0.0 4.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAK68412.1 - 0.0051 16.2 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Methyltransf_31 PF13847.6 GAK68413.1 - 1.5e-07 31.3 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAK68413.1 - 1.6e-05 25.5 0.0 3.7e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAK68413.1 - 0.0001 22.9 0.0 0.00022 21.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAK68413.1 - 0.00017 22.2 0.0 0.00042 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAK68413.1 - 0.00018 21.4 0.0 0.00059 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 GAK68413.1 - 0.0036 17.0 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) BRO1 PF03097.18 GAK68414.1 - 1.1e-119 399.7 0.0 1.9e-119 399.0 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAK68414.1 - 9.2e-77 258.2 2.3 9.2e-77 258.2 2.3 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF3294 PF07957.11 GAK68414.1 - 0.0043 16.8 0.7 0.013 15.3 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Spt20 PF12090.8 GAK68414.1 - 0.17 11.5 12.5 0.097 12.3 10.4 1.6 2 0 0 2 2 2 0 Spt20 family WGG PF10273.9 GAK68415.1 - 1.9e-20 73.3 0.0 4e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Sugar_tr PF00083.24 GAK68417.1 - 1.4e-83 281.3 18.9 1.7e-83 281.0 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAK68417.1 - 3e-16 59.3 23.4 3e-16 59.3 23.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAK68417.1 - 3.5e-05 23.3 5.4 3.5e-05 23.3 5.4 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TPR_4 PF07721.14 GAK68417.1 - 0.053 14.2 0.5 0.14 12.8 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1_like PF12832.7 GAK68417.1 - 0.43 9.4 14.6 0.02 13.8 4.5 2.3 2 0 0 2 2 2 0 MFS_1 like family Phage_holin_2_4 PF16082.5 GAK68417.1 - 1.9 8.2 4.2 53 3.6 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like YIF1 PF03878.15 GAK68418.1 - 2e-93 312.3 0.2 2.4e-93 312.1 0.2 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 GAK68418.1 - 0.0064 16.2 11.5 0.025 14.3 11.7 1.8 1 1 0 1 1 1 1 Yip1 domain UCR_14kD PF02271.16 GAK68419.1 - 8.6e-40 134.8 1.7 1e-39 134.5 1.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Methyltransf_28 PF02636.17 GAK68420.1 - 4.3e-74 249.5 0.0 7.7e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Amino_oxidase PF01593.24 GAK68420.1 - 5.3e-41 141.4 0.0 7.3e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAK68420.1 - 2.1e-11 43.8 0.0 5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK68420.1 - 2.6e-08 33.8 0.0 6.3e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAK68420.1 - 4.1e-08 32.8 0.0 0.0083 15.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAK68420.1 - 7.4e-06 24.9 0.0 0.0074 15.0 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 GAK68420.1 - 0.00013 21.9 0.2 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAK68420.1 - 0.011 14.6 0.0 0.031 13.1 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 GAK68420.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GAK68420.1 - 0.028 13.5 0.0 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain TPR_14 PF13428.6 GAK68422.1 - 1.6e-08 34.7 9.0 0.0035 18.1 0.5 5.0 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAK68422.1 - 5e-05 23.1 5.5 0.075 13.2 0.3 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAK68422.1 - 0.00012 22.2 1.1 0.76 10.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAK68422.1 - 0.00013 22.4 5.5 1.2 9.7 2.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAK68422.1 - 0.0002 21.9 2.5 0.82 10.4 2.8 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK68422.1 - 0.00044 20.3 7.0 0.59 10.3 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK68422.1 - 0.033 14.4 2.4 0.1 12.8 2.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAK68422.1 - 0.22 11.3 0.8 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 GAK68422.1 - 0.39 11.1 3.2 7.1 7.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAK68422.1 - 2.9 8.7 5.6 40 5.1 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TIM PF00121.18 GAK68424.1 - 6.2e-55 186.2 0.0 7.4e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 GAK68425.1 - 1.5e-44 151.4 0.3 1.7e-44 151.2 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.6 GAK68425.1 - 0.021 14.8 1.4 0.061 13.3 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) Arm PF00514.23 GAK68426.1 - 0.0002 21.3 1.9 0.002 18.1 0.1 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Zn_clus PF00172.18 GAK68427.1 - 1.1e-06 28.6 12.7 2.1e-06 27.7 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 GAK68428.1 - 1.7e-08 34.2 0.1 0.00092 18.7 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAK68428.1 - 1.2e-07 31.2 0.0 0.0034 16.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAK68428.1 - 0.00014 21.8 0.8 0.00038 20.4 0.8 1.8 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GAK68428.1 - 0.00021 21.0 0.1 0.0006 19.4 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAK68428.1 - 0.00044 19.8 0.3 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAK68428.1 - 0.00069 18.8 0.1 0.053 12.6 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 GAK68428.1 - 0.0012 18.3 0.4 0.066 12.7 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAK68428.1 - 0.044 13.7 0.5 0.9 9.4 0.1 2.2 1 1 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 GAK68428.1 - 0.048 12.7 0.1 0.31 10.0 0.0 2.2 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pirin_C PF05726.13 GAK68428.1 - 0.14 12.5 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Pirin C-terminal cupin domain Abhydrolase_6 PF12697.7 GAK68429.1 - 8.7e-16 59.2 0.7 1.6e-15 58.3 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAK68429.1 - 1e-14 54.8 0.1 3.1e-11 43.4 0.1 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAK68429.1 - 8.6e-07 28.5 0.0 0.00025 20.4 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 GAK68429.1 - 0.00058 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Rad60-SLD_2 PF13881.6 GAK68430.1 - 5.5e-14 52.2 0.3 2.2e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.32 GAK68431.1 - 2e-20 72.7 0.1 1e-06 29.3 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Dopey_N PF04118.14 GAK68433.1 - 2.2e-107 358.8 0.1 5e-107 357.6 0.1 1.7 1 0 0 1 1 1 1 Dopey, N-terminal RRM_1 PF00076.22 GAK68434.1 - 3.4e-15 55.6 0.0 5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK68434.1 - 0.00038 20.1 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAK68434.1 - 0.0099 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Uds1 PF15456.6 GAK68435.1 - 1.1e-34 119.4 4.4 1.1e-34 119.4 4.4 10.1 6 2 4 10 10 10 1 Up-regulated During Septation ABC_tran_CTD PF16326.5 GAK68435.1 - 0.011 15.9 1.6 0.011 15.9 1.6 11.9 7 2 3 12 12 12 0 ABC transporter C-terminal domain PKcGMP_CC PF16808.5 GAK68435.1 - 0.014 15.3 0.1 0.014 15.3 0.1 7.2 8 1 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase COPIIcoated_ERV PF07970.12 GAK68436.1 - 6.8e-84 281.1 0.3 1e-83 280.6 0.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAK68436.1 - 1.6e-28 98.8 0.0 4.8e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) WD40 PF00400.32 GAK68437.1 - 7e-25 86.8 7.0 9.7e-05 23.1 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68437.1 - 5.3e-17 61.9 7.3 4e-07 30.3 0.4 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAK68437.1 - 1.5e-06 28.2 0.4 0.00013 21.9 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A HPP PF04982.13 GAK68438.1 - 1.7e-34 118.6 9.1 3.6e-34 117.6 9.1 1.6 1 0 0 1 1 1 1 HPP family YL1_C PF08265.11 GAK68438.1 - 0.026 14.3 0.2 0.061 13.1 0.1 1.6 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Ebola_NP PF05505.12 GAK68438.1 - 2.3 6.4 4.6 3.6 5.8 4.6 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Fis1_TPR_C PF14853.6 GAK68439.1 - 5.7e-25 87.1 0.6 8.8e-25 86.5 0.6 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAK68439.1 - 1.2e-16 60.1 0.0 2.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 GAK68439.1 - 0.00033 20.5 0.2 0.00082 19.3 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAK68439.1 - 0.079 13.6 0.0 0.25 12.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat COPI_C PF06957.11 GAK68439.1 - 0.13 11.0 0.0 0.26 10.0 0.0 1.4 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus PX PF00787.24 GAK68440.1 - 1.7e-21 76.3 0.4 3.2e-21 75.4 0.4 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 GAK68440.1 - 0.00055 19.6 0.7 7.4 6.0 0.3 3.1 3 0 0 3 3 3 3 Vps5 C terminal like HMG_box PF00505.19 GAK68442.1 - 2.6e-18 66.2 13.9 9.6e-11 42.0 0.8 3.6 2 2 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAK68442.1 - 1.5e-16 60.8 11.9 8.7e-10 39.1 0.4 3.0 3 0 0 3 3 3 2 HMG-box domain MlaC PF05494.12 GAK68442.1 - 0.02 14.6 2.7 0.44 10.3 0.3 2.3 2 0 0 2 2 2 0 MlaC protein KRAB PF01352.27 GAK68442.1 - 0.14 11.9 2.0 9.2 6.0 0.1 2.4 2 0 0 2 2 2 0 KRAB box GCV_T PF01571.21 GAK68444.1 - 2.3e-07 30.4 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Aim19 PF10315.9 GAK68446.1 - 1.7e-17 63.8 5.2 1.4e-16 60.8 5.2 2.1 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Chitin_synth_2 PF03142.15 GAK68447.1 - 5.3e-257 853.6 0.1 7.2e-257 853.2 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 GAK68447.1 - 7.8e-23 80.4 0.2 4e-16 58.9 0.0 2.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 GAK68447.1 - 3.9e-18 65.1 0.1 1.3e-15 57.0 0.1 2.8 3 0 0 3 3 3 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 GAK68447.1 - 2.3e-10 40.7 0.0 2.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAK68447.1 - 6.9e-10 39.2 6.2 6.9e-10 39.2 6.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAK68447.1 - 1e-05 25.4 0.0 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAK68447.1 - 0.00032 20.2 0.0 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Jiv90 PF14901.6 GAK68447.1 - 0.0054 16.9 0.2 0.7 10.1 0.0 2.5 2 0 0 2 2 2 1 Cleavage inducing molecular chaperone DUF1622 PF07784.11 GAK68447.1 - 0.3 11.0 1.5 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) Glyco_hydro_63 PF03200.16 GAK68448.1 - 1e-07 31.1 5.6 6e-06 25.3 0.1 4.3 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Pro_isomerase PF00160.21 GAK68449.1 - 1.7e-33 116.2 0.0 3.2e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 GAK68449.1 - 1.5e-05 25.5 0.1 1.5e-05 25.5 0.1 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4604) RNA_pol_Rbc25 PF08292.12 GAK68449.1 - 0.93 9.7 3.6 0.28 11.4 0.3 1.7 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 NUDIX PF00293.28 GAK68450.1 - 4.8e-09 36.3 0.0 7.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb6 PF01192.22 GAK68450.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb6 RRM_1 PF00076.22 GAK68451.1 - 5e-15 55.1 0.1 7.7e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK68451.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 GAK68451.1 - 0.045 13.7 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 RL domain SAGA-Tad1 PF12767.7 GAK68451.1 - 0.052 13.3 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RRM_7 PF16367.5 GAK68451.1 - 0.074 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif F-box PF00646.33 GAK68452.1 - 0.0038 17.1 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAK68452.1 - 0.009 15.9 0.1 0.025 14.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like CDC45 PF02724.14 GAK68452.1 - 0.067 11.5 5.9 0.11 10.7 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 GAK68452.1 - 0.14 11.9 20.3 0.037 13.7 13.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GAK68452.1 - 0.16 10.2 5.4 0.25 9.5 5.4 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GAK68452.1 - 0.9 9.4 8.8 2.8 7.8 8.8 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 GAK68452.1 - 1.7 8.3 9.4 3.2 7.4 7.3 2.4 2 0 0 2 2 2 0 FAM176 family PPP4R2 PF09184.11 GAK68452.1 - 2.6 7.5 8.5 0.37 10.4 3.4 2.0 2 0 0 2 2 2 0 PPP4R2 DUF3537 PF12056.8 GAK68452.1 - 3.1 6.5 3.5 4.6 5.9 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) RXT2_N PF08595.11 GAK68452.1 - 3.7 7.6 10.5 2.7 8.0 7.8 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal RRN3 PF05327.11 GAK68452.1 - 7.9 4.9 12.7 12 4.2 12.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EF-hand_1 PF00036.32 GAK68453.1 - 5.7e-42 138.2 12.2 4.4e-10 38.4 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAK68453.1 - 1.2e-35 121.8 2.4 4.5e-18 65.5 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAK68453.1 - 1.1e-31 108.4 11.5 3.6e-15 55.5 0.5 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAK68453.1 - 2e-31 105.2 7.4 1.3e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAK68453.1 - 8.4e-27 91.5 9.4 9.6e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAK68453.1 - 1.3e-15 57.4 0.1 2e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAK68453.1 - 3.1e-10 39.9 1.2 3.9e-05 23.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAK68453.1 - 1.5e-08 35.0 0.0 0.0011 19.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 GAK68453.1 - 1.9e-06 27.8 0.0 0.039 14.0 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 GAK68453.1 - 1.2e-05 26.2 0.0 0.0044 17.9 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 GAK68453.1 - 0.00016 21.8 5.9 0.059 13.6 2.9 3.1 1 1 1 2 2 2 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 GAK68453.1 - 0.00019 21.5 0.5 0.0013 18.8 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 GAK68453.1 - 0.00088 18.9 1.4 0.001 18.7 1.4 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 GAK68453.1 - 0.0011 18.9 0.8 0.57 10.1 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 GAK68453.1 - 0.0011 19.6 0.3 0.91 10.3 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 GAK68453.1 - 0.0022 18.4 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 GAK68453.1 - 0.0028 17.8 0.1 0.66 10.2 0.0 3.0 1 1 1 3 3 3 1 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.16 GAK68453.1 - 0.0068 16.7 0.2 3.7 7.9 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 MotA_activ PF09114.10 GAK68453.1 - 0.0078 16.3 0.5 0.11 12.7 0.1 2.2 1 1 0 2 2 2 1 Transcription factor MotA, activation domain TerB PF05099.13 GAK68453.1 - 0.009 16.0 0.3 0.98 9.4 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF5580 PF17743.1 GAK68453.1 - 0.018 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SapB_1 PF05184.15 GAK68453.1 - 0.022 14.8 1.8 18 5.5 0.0 3.7 4 0 0 4 4 4 0 Saposin-like type B, region 1 dCache_2 PF08269.11 GAK68453.1 - 0.028 13.6 0.1 1.3 8.1 0.1 2.3 1 1 1 2 2 2 0 Cache domain SurA_N_2 PF13623.6 GAK68453.1 - 0.034 14.0 0.9 1 9.3 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 GAK68453.1 - 0.048 13.3 0.2 0.084 12.5 0.2 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 GAK68453.1 - 0.049 14.0 0.1 14 6.1 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF1811 PF08838.10 GAK68453.1 - 0.065 13.5 0.0 17 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) RuvA_C PF07499.13 GAK68453.1 - 0.14 12.6 0.1 15 6.1 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain RloB PF13707.6 GAK68453.1 - 0.23 11.6 1.2 1.6 8.9 1.1 2.1 1 1 0 1 1 1 0 RloB-like protein Mito_carr PF00153.27 GAK68454.1 - 9e-64 211.5 9.2 2.9e-22 78.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein GPI-anchored PF10342.9 GAK68455.1 - 3.1e-09 37.5 0.1 4.9e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_7 PF17957.1 GAK68455.1 - 0.00028 21.6 0.6 0.00085 20.0 0.6 1.8 1 1 0 1 1 1 1 Bacterial Ig domain AAA PF00004.29 GAK68456.1 - 2.2e-43 147.8 0.0 3.7e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAK68456.1 - 1.1e-10 41.2 0.1 2.2e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAK68456.1 - 7.2e-10 38.7 0.1 1.5e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 GAK68456.1 - 4.7e-07 30.4 0.0 0.00014 22.3 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAK68456.1 - 6e-07 29.5 0.1 1.3e-05 25.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAK68456.1 - 8e-07 29.3 0.0 6e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAK68456.1 - 8e-06 25.7 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAK68456.1 - 0.00017 21.8 0.1 0.0048 17.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 GAK68456.1 - 0.00071 20.1 0.1 0.0063 17.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAK68456.1 - 0.00076 18.7 0.0 0.0018 17.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAK68456.1 - 0.0011 18.6 0.0 0.0024 17.4 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 GAK68456.1 - 0.0026 17.5 0.2 0.017 14.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 GAK68456.1 - 0.0029 17.0 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 GAK68456.1 - 0.0039 16.5 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 GAK68456.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 GAK68456.1 - 0.0059 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 GAK68456.1 - 0.0059 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAK68456.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAK68456.1 - 0.0078 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAK68456.1 - 0.0085 15.8 0.0 0.029 14.1 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain YkyA PF10368.9 GAK68456.1 - 0.013 15.2 0.7 0.03 14.0 0.7 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein AAA_3 PF07726.11 GAK68456.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAK68456.1 - 0.03 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAK68456.1 - 0.037 13.9 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 GAK68456.1 - 0.048 13.0 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 GAK68456.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 GAK68456.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 GAK68456.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.12 GAK68456.1 - 0.1 12.5 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Prot_ATP_OB_N PF17758.1 GAK68456.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_11 PF13086.6 GAK68456.1 - 0.11 12.2 0.3 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAK68456.1 - 0.15 11.6 0.1 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAK68456.1 - 0.2 12.1 2.5 28 5.1 2.2 2.5 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 GAK68456.1 - 8.8 6.3 6.8 0.74 9.7 0.9 2.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Clathrin PF00637.20 GAK68457.1 - 1.8e-208 682.8 28.2 4.8e-33 114.0 0.0 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 GAK68457.1 - 2.5e-37 125.4 1.2 3.7e-08 33.3 0.1 6.7 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 GAK68457.1 - 2.9e-33 113.6 0.1 3.5e-32 110.1 0.1 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 GAK68457.1 - 7.6e-12 44.4 0.2 2.1e-11 43.0 0.2 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 GAK68457.1 - 0.0022 17.1 4.1 0.16 11.0 0.0 4.7 5 0 0 5 5 5 1 Coatomer WD associated region Vps39_1 PF10366.9 GAK68457.1 - 0.0044 17.3 3.9 13 6.1 0.0 5.2 3 2 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.6 GAK68457.1 - 0.0067 17.2 11.7 13 6.9 0.1 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAK68457.1 - 0.02 14.7 3.0 15 5.6 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAK68457.1 - 0.33 11.2 10.7 43 4.6 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAK68457.1 - 2.1 8.5 8.7 29 5.0 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Opi1 PF08618.10 GAK68458.1 - 1.9e-101 340.4 5.8 1.9e-101 340.4 5.8 3.1 3 0 0 3 3 3 1 Transcription factor Opi1 REF PF05755.12 GAK68458.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Perilipin PF03036.16 GAK68458.1 - 0.17 10.9 2.0 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Perilipin family DUF1104 PF06518.11 GAK68458.1 - 2.5 8.6 5.1 5.3 7.5 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Cullin PF00888.22 GAK68459.1 - 1.2e-194 648.4 0.0 2.3e-194 647.5 0.0 1.5 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAK68459.1 - 6.9e-26 90.1 1.1 2.1e-25 88.5 1.1 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain TetR_C_29 PF17938.1 GAK68459.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MarR PF01047.22 GAK68459.1 - 0.15 12.0 0.4 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 MarR family Ndufs5 PF10200.9 GAK68459.1 - 0.17 12.2 0.0 0.79 10.0 0.0 2.1 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa VPS28 PF03997.12 GAK68459.1 - 0.2 11.3 1.1 3.3 7.4 0.4 2.6 2 1 0 2 2 2 0 VPS28 protein Zn_clus PF00172.18 GAK68461.1 - 2.2e-05 24.5 6.7 3.9e-05 23.7 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L44 PF00935.19 GAK68461.1 - 0.032 14.7 0.6 0.069 13.6 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L44 Methyltransf_10 PF05971.12 GAK68462.1 - 2.1e-37 129.1 0.0 8e-30 104.2 0.0 2.2 1 1 1 2 2 2 2 RNA methyltransferase CENP-O PF09496.10 GAK68462.1 - 1.3e-35 123.4 0.0 2.1e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component HALZ PF02183.18 GAK68462.1 - 0.022 15.0 3.3 1.5 9.1 0.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper cNMP_binding PF00027.29 GAK68463.1 - 3.7e-37 126.3 2.0 1.3e-17 63.6 0.1 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 GAK68463.1 - 8.5e-15 54.1 0.3 1.6e-14 53.2 0.3 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.11 GAK68463.1 - 0.11 12.2 1.0 0.84 9.4 0.1 2.6 3 0 0 3 3 3 0 Cupin domain Mt_ATP-synt_D PF05873.12 GAK68464.1 - 3.7e-11 43.1 1.3 1.2e-06 28.4 0.2 2.2 2 0 0 2 2 2 2 ATP synthase D chain, mitochondrial (ATP5H) PLU-1 PF08429.11 GAK68464.1 - 0.034 13.3 0.5 0.034 13.3 0.5 1.5 2 0 0 2 2 2 0 PLU-1-like protein EzrA PF06160.12 GAK68464.1 - 0.039 12.1 2.1 0.18 10.0 0.4 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2408 PF10303.9 GAK68464.1 - 0.13 12.9 1.3 2.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) GAS PF13851.6 GAK68464.1 - 0.16 11.3 4.9 0.43 9.9 1.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 GAK68464.1 - 0.39 11.0 2.1 3.1 8.1 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2570 PF10828.8 GAK68464.1 - 0.79 9.6 4.4 0.43 10.4 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DivIC PF04977.15 GAK68464.1 - 1.9 8.3 4.9 4.5 7.1 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Ribosomal_S25 PF03297.15 GAK68465.1 - 8.5e-39 131.8 1.7 9.2e-39 131.7 1.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 GAK68465.1 - 0.0055 16.2 0.2 0.0099 15.4 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 GAK68465.1 - 0.055 13.4 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 MarR family BolA PF01722.18 GAK68466.1 - 3.3e-12 46.5 0.0 9.7e-12 45.0 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein GTP_cyclohydroI PF01227.22 GAK68467.1 - 3.2e-73 245.0 0.2 4.2e-73 244.6 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 GAK68467.1 - 0.0037 17.4 0.0 0.011 15.9 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 GAK68467.1 - 0.025 14.6 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MutS_II PF05188.17 GAK68468.1 - 6.4e-05 23.2 0.0 0.00014 22.2 0.0 1.5 2 0 0 2 2 2 1 MutS domain II WD40 PF00400.32 GAK68469.1 - 2.3e-27 94.7 21.6 1.4e-06 28.9 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAK68469.1 - 1.2e-11 44.7 0.2 2.5e-05 24.5 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAK68469.1 - 0.00018 20.9 0.0 0.00066 19.1 0.0 1.9 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 GAK68469.1 - 0.00059 18.9 0.8 2.5 7.0 0.0 4.0 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 GAK68469.1 - 0.002 16.5 0.0 0.0053 15.1 0.0 1.6 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 GAK68469.1 - 0.0084 14.2 0.1 0.015 13.4 0.0 1.3 1 1 0 1 1 1 1 IKI3 family PQQ_3 PF13570.6 GAK68469.1 - 0.11 13.1 12.9 1.3 9.6 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain Nup160 PF11715.8 GAK68469.1 - 0.25 9.9 0.0 0.66 8.6 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.25 GAK68470.1 - 2.7e-54 184.3 0.0 6e-54 183.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.8 GAK68470.1 - 9.3e-51 172.6 0.0 1.8e-50 171.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 GAK68470.1 - 1.6e-40 139.0 0.0 4.2e-40 137.7 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAK68470.1 - 0.043 12.6 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF3425 PF11905.8 GAK68471.1 - 2.7e-16 59.7 0.0 5.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAK68471.1 - 0.00041 20.4 12.2 0.00073 19.6 12.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 GAK68471.1 - 0.0045 17.5 10.9 0.0083 16.6 10.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 GAK68471.1 - 0.25 11.5 14.8 0.46 10.6 14.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DJ-1_PfpI PF01965.24 GAK68472.1 - 3e-05 23.9 0.0 0.00012 22.0 0.0 1.9 2 1 0 2 2 2 1 DJ-1/PfpI family RVT_1 PF00078.27 GAK68473.1 - 4.1e-06 26.5 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trypan_PARP PF05887.11 GAK68473.1 - 0.065 13.2 11.7 0.11 12.5 11.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 GAK68473.1 - 7.4 4.9 18.2 11 4.4 18.2 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF218 PF02698.17 GAK68475.1 - 0.11 12.5 0.1 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain Ribosomal_L7Ae PF01248.26 GAK68476.1 - 3.3e-27 94.1 0.1 4.1e-27 93.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 GAK68476.1 - 0.002 17.9 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 GAK68476.1 - 0.0074 16.3 0.0 0.0088 16.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 MutS_V PF00488.21 GAK68477.1 - 1.5e-50 171.8 0.1 2.5e-50 171.1 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAK68477.1 - 2.6e-16 60.4 1.8 3.2e-15 56.9 0.2 2.9 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 GAK68477.1 - 0.00018 21.8 0.2 0.00035 20.9 0.2 1.5 1 0 0 1 1 1 1 MutS family domain IV G-alpha PF00503.20 GAK68477.1 - 0.0031 16.7 0.4 1.8 7.7 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 GAK68477.1 - 0.0047 16.6 0.2 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GAK68477.1 - 0.0086 16.6 0.2 0.035 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAK68477.1 - 0.11 12.8 1.5 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 GAK68477.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.15 GAK68478.1 - 1.3e-19 69.6 3.8 1.3e-19 69.6 3.8 1.7 1 1 1 2 2 2 1 Tim10/DDP family zinc finger eIF-6 PF01912.18 GAK68479.1 - 7.8e-81 270.2 0.4 1.3e-80 269.5 0.2 1.4 1 1 1 2 2 2 1 eIF-6 family PRKCSH-like PF12999.7 GAK68480.1 - 1.2e-51 174.9 4.6 1.2e-51 174.9 4.6 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 GAK68480.1 - 2.9e-31 108.2 0.2 1.2e-30 106.3 0.1 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 GAK68480.1 - 2.8e-10 41.1 0.7 5.7e-10 40.1 0.7 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Effector_1 PF04518.12 GAK68480.1 - 0.034 13.3 0.8 0.058 12.5 0.8 1.2 1 0 0 1 1 1 0 Effector from type III secretion system ATG27 PF09451.10 GAK68480.1 - 0.054 13.3 0.1 0.054 13.3 0.1 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 DivIVA PF05103.13 GAK68480.1 - 0.073 13.2 5.1 15 5.6 5.9 2.8 2 1 0 2 2 2 0 DivIVA protein GAS PF13851.6 GAK68480.1 - 0.19 11.0 4.4 0.092 12.1 1.9 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.13 GAK68480.1 - 0.33 11.1 1.0 15 5.7 0.3 2.5 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PriC PF07445.12 GAK68480.1 - 0.47 10.4 5.0 0.25 11.2 1.6 2.1 2 0 0 2 2 2 0 Primosomal replication protein priC Enkurin PF13864.6 GAK68480.1 - 0.52 10.8 3.4 5.1 7.6 2.3 2.4 1 1 1 2 2 2 0 Calmodulin-binding MBF1 PF08523.10 GAK68480.1 - 0.85 10.1 5.0 1.2 9.7 0.5 2.7 2 0 0 2 2 2 0 Multiprotein bridging factor 1 Cnn_1N PF07989.11 GAK68480.1 - 2.3 8.4 6.3 25 5.1 0.1 3.4 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 GAK68480.1 - 4.3 6.1 6.7 3.4 6.5 3.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 GAK68480.1 - 6.4 6.6 11.1 4 7.3 1.4 2.6 2 1 1 3 3 3 0 Septum formation initiator Tctex-1 PF03645.13 GAK68481.1 - 0.0075 16.5 0.0 0.023 14.9 0.0 1.9 1 1 0 1 1 1 1 Tctex-1 family EnY2 PF10163.9 GAK68482.1 - 6.6e-20 71.3 0.0 7.6e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 RNA_Me_trans PF04252.13 GAK68483.1 - 7.2e-73 244.4 0.0 8.7e-73 244.2 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.25 GAK68484.1 - 9.5e-67 225.1 0.0 1.4e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68484.1 - 1.5e-34 119.5 0.0 2.4e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 GAK68484.1 - 0.00087 19.0 0.1 0.0058 16.3 0.0 2.2 2 0 0 2 2 2 1 Fungal kinase associated-1 domain APH PF01636.23 GAK68484.1 - 0.0013 18.7 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAK68484.1 - 0.0045 16.4 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAK68484.1 - 0.007 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 GAK68484.1 - 0.047 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase HIG_1_N PF04588.13 GAK68485.1 - 1.6e-07 31.4 0.7 2.9e-07 30.6 0.7 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region NDUF_B8 PF05821.11 GAK68487.1 - 5.2e-08 32.9 0.2 1.5e-07 31.5 0.2 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Metallophos PF00149.28 GAK68488.1 - 2.5e-33 116.3 0.2 9.5e-33 114.4 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAK68488.1 - 8.7e-05 22.9 0.1 0.00018 21.8 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain cwf21 PF08312.12 GAK68488.1 - 0.23 11.7 0.3 0.42 10.8 0.3 1.5 1 0 0 1 1 1 0 cwf21 domain ELO PF01151.18 GAK68489.1 - 7e-59 199.4 17.1 9.2e-59 199.0 17.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Methyltransf_16 PF10294.9 GAK68490.1 - 1.4e-16 60.7 0.0 4.5e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAK68490.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ABC_tran PF00005.27 GAK68494.1 - 4.5e-44 150.3 0.1 1.3e-21 77.5 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAK68494.1 - 3.1e-16 60.1 0.2 0.0072 16.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAK68494.1 - 7e-12 45.2 2.1 0.23 10.9 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAK68494.1 - 4.1e-09 36.0 0.7 0.0026 17.5 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.6 GAK68494.1 - 1.2e-06 28.8 0.6 0.046 14.1 0.1 4.3 3 1 1 4 4 4 2 HEAT repeats CLASP_N PF12348.8 GAK68494.1 - 9.7e-06 25.3 0.0 5.6e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 CLASP N terminal AAA_22 PF13401.6 GAK68494.1 - 1.9e-05 24.9 0.1 0.18 12.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain Chromo PF00385.24 GAK68494.1 - 2.8e-05 23.9 0.1 6.6e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 GAK68494.1 - 3e-05 24.6 11.6 0.0069 16.9 0.0 3.8 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 GAK68494.1 - 6.8e-05 22.9 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 GAK68494.1 - 0.00011 22.7 0.1 0.059 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAK68494.1 - 0.00023 21.6 0.1 3.7 8.0 0.0 4.8 5 1 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) HEAT_EZ PF13513.6 GAK68494.1 - 0.00032 21.1 0.8 0.012 16.1 0.1 3.9 3 1 1 4 4 3 1 HEAT-like repeat HEAT PF02985.22 GAK68494.1 - 0.00045 20.2 2.2 0.27 11.6 0.0 4.8 5 0 0 5 5 3 1 HEAT repeat AAA_28 PF13521.6 GAK68494.1 - 0.00053 20.3 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAK68494.1 - 0.00075 19.4 0.2 0.99 9.3 0.0 2.8 3 0 0 3 3 2 1 NACHT domain RsgA_GTPase PF03193.16 GAK68494.1 - 0.0012 18.8 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase 4HB PF17947.1 GAK68494.1 - 0.0013 18.7 0.1 0.0041 17.1 0.1 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_16 PF13191.6 GAK68494.1 - 0.0017 18.8 0.2 0.99 9.8 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain DUF87 PF01935.17 GAK68494.1 - 0.0019 18.3 5.4 0.21 11.7 0.1 3.9 4 0 0 4 4 4 1 Helicase HerA, central domain G-alpha PF00503.20 GAK68494.1 - 0.0019 17.4 0.0 0.41 9.7 0.0 2.5 2 0 0 2 2 2 1 G-protein alpha subunit NB-ARC PF00931.22 GAK68494.1 - 0.0021 17.3 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 GAK68494.1 - 0.0023 18.1 0.1 3 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAK68494.1 - 0.0042 17.5 0.0 5.2 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 GAK68494.1 - 0.0056 16.4 0.0 0.61 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAK68494.1 - 0.0089 15.8 8.5 0.29 10.8 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain Cnd1 PF12717.7 GAK68494.1 - 0.0092 16.0 0.4 0.38 10.8 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 GAK68494.1 - 0.0095 15.8 1.9 1.7 8.6 0.8 3.1 2 1 1 3 3 3 1 UME (NUC010) domain MeaB PF03308.16 GAK68494.1 - 0.014 14.4 1.7 0.55 9.2 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 GAK68494.1 - 0.015 15.3 5.3 23 5.0 0.1 5.1 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 GAK68494.1 - 0.018 15.3 0.2 0.91 9.8 0.0 3.4 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DRIM PF07539.12 GAK68494.1 - 0.019 13.3 1.0 0.54 8.5 0.1 2.4 1 1 0 2 2 2 0 Down-regulated in metastasis Roc PF08477.13 GAK68494.1 - 0.034 14.4 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 GAK68494.1 - 0.043 13.7 0.1 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 GAK68494.1 - 0.047 13.1 0.9 22 4.4 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAK68494.1 - 0.051 13.3 7.3 11 5.7 0.1 3.9 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.13 GAK68494.1 - 0.062 12.4 1.3 8 5.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 GAK68494.1 - 0.085 12.2 0.4 11 5.2 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 GAK68494.1 - 0.12 11.8 0.2 14 5.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3584 PF12128.8 GAK68494.1 - 0.22 9.0 8.6 0.41 8.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) ATP_bind_1 PF03029.17 GAK68494.1 - 0.23 11.2 1.8 9.3 5.9 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Arm PF00514.23 GAK68494.1 - 0.24 11.5 0.8 38 4.5 0.0 3.5 4 0 0 4 4 2 0 Armadillo/beta-catenin-like repeat CLP1_P PF16575.5 GAK68494.1 - 0.46 10.3 2.1 17 5.2 0.0 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 GAK68494.1 - 1.4 8.5 4.1 20 4.7 0.1 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 GAK68494.1 - 1.5 7.4 7.0 2.9 6.4 0.0 3.1 4 0 0 4 4 3 0 AAA domain ATPase_2 PF01637.18 GAK68494.1 - 5.2 6.9 10.9 10 5.9 0.0 3.9 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea Pkinase PF00069.25 GAK68495.1 - 3.8e-09 36.3 0.0 5.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68495.1 - 1.1e-05 24.8 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.6 GAK68496.1 - 2.9e-06 27.3 3.0 0.018 15.1 0.2 3.0 2 1 1 3 3 3 2 HNH endonuclease GMC_oxred_N PF00732.19 GAK68497.1 - 1.8e-71 240.9 0.1 2.5e-71 240.5 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAK68497.1 - 5.2e-31 108.1 0.0 1.2e-30 106.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAK68497.1 - 2.3e-05 23.6 0.5 4.4e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAK68497.1 - 2.8e-05 24.3 0.0 0.00013 22.1 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAK68497.1 - 5.7e-05 22.9 1.6 0.001 18.7 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAK68497.1 - 0.00017 20.8 1.4 0.00058 19.0 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAK68497.1 - 0.0015 17.8 0.4 0.0032 16.8 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Collagen PF01391.18 GAK68497.1 - 0.0031 17.3 10.2 0.0061 16.3 10.2 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pyr_redox_2 PF07992.14 GAK68497.1 - 0.0063 15.8 0.7 0.011 15.0 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAK68497.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.25 GAK68498.1 - 4.7e-63 213.0 4.5 1.3e-43 149.3 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68498.1 - 2.8e-24 85.8 8.4 4.1e-20 72.1 0.0 2.8 3 0 0 3 3 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAK68498.1 - 5.8e-07 28.8 0.0 5.8e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain TFIIA PF03153.13 GAK68498.1 - 0.0026 17.8 50.9 0.0049 16.9 50.9 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kdo PF06293.14 GAK68498.1 - 0.014 14.8 0.0 0.014 14.8 0.0 2.2 3 0 0 3 3 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAK68498.1 - 0.055 12.2 0.0 0.055 12.2 0.0 2.3 2 1 0 2 2 1 0 Fungal protein kinase APH PF01636.23 GAK68498.1 - 0.062 13.2 0.1 0.062 13.2 0.1 4.1 1 1 2 3 3 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAK68498.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase eIF-3_zeta PF05091.12 GAK68498.1 - 0.15 11.0 13.3 0.27 10.2 13.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase_C PF00433.24 GAK68498.1 - 0.16 12.7 0.2 0.46 11.2 0.2 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 GAK68498.1 - 0.18 10.8 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ALMT PF11744.8 GAK68498.1 - 4 6.2 5.3 6.7 5.4 5.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PRP3 PF08572.10 GAK68498.1 - 7.9 6.1 19.7 0.27 10.9 12.8 1.9 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) AAA_23 PF13476.6 GAK68498.1 - 8 6.9 15.3 1.6 9.2 9.4 2.4 3 0 0 3 3 3 0 AAA domain Myosin_head PF00063.21 GAK68499.1 - 4.4e-239 795.2 3.9 5.4e-239 794.9 3.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAK68499.1 - 2.1e-52 177.6 0.1 3.8e-52 176.7 0.1 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 GAK68499.1 - 6.2e-11 42.0 0.1 1.5e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAK68499.1 - 6.9e-10 38.4 1.7 1e-09 37.8 0.4 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 GAK68499.1 - 9.3e-09 34.8 0.1 2.1e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 GAK68499.1 - 0.0012 19.1 0.9 0.003 17.8 0.9 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.6 GAK68499.1 - 0.034 14.4 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 GAK68499.1 - 0.07 12.6 0.3 9 5.8 0.0 2.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 GAK68499.1 - 0.08 13.3 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 GAK68499.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Tad PF13400.6 GAK68499.1 - 0.9 9.9 4.2 2.6 8.4 4.2 1.8 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Melibiase PF02065.18 GAK68500.1 - 8e-115 383.5 0.0 1e-114 383.1 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 GAK68500.1 - 2.8e-39 135.2 0.0 3.9e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 GAK68500.1 - 2.5e-09 37.5 0.0 5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain Pkinase PF00069.25 GAK68501.1 - 3.8e-49 167.4 0.0 5.6e-49 166.9 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68501.1 - 1.4e-32 113.0 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK68501.1 - 2.1e-05 24.6 0.1 7.4e-05 22.8 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAK68501.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 GAK68501.1 - 0.043 12.6 0.0 0.076 11.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase DUF4667 PF15700.5 GAK68502.1 - 0.00073 19.7 5.6 0.0012 19.0 5.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) RecQ5 PF06959.11 GAK68502.1 - 0.0016 18.4 0.3 0.0016 18.4 0.3 2.1 2 0 0 2 2 1 1 RecQ helicase protein-like 5 (RecQ5) AF-4 PF05110.13 GAK68502.1 - 0.015 13.4 20.1 0.018 13.2 20.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 GAK68502.1 - 0.028 13.0 4.9 0.035 12.7 4.9 1.1 1 0 0 1 1 1 0 Macoilin family HSD3 PF15244.6 GAK68502.1 - 0.25 10.8 6.6 0.38 10.2 6.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Apt1 PF10351.9 GAK68502.1 - 0.61 8.9 7.6 0.8 8.5 7.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Herpes_pp85 PF04637.12 GAK68502.1 - 2.2 6.6 10.4 3 6.2 10.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) NAM-associated PF14303.6 GAK68502.1 - 2.6 8.7 11.2 18 6.0 7.8 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain CCDC106 PF15794.5 GAK68502.1 - 3.2 7.4 8.1 5.7 6.6 8.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 GAK68502.1 - 3.2 7.6 13.1 5.7 6.7 12.8 1.5 1 1 0 1 1 1 0 SPX domain Herpes_capsid PF06112.11 GAK68502.1 - 5.1 7.1 18.0 13 5.8 18.0 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RSRP PF17069.5 GAK68502.1 - 6 6.3 25.7 10 5.6 25.7 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF4614 PF15391.6 GAK68502.1 - 6.1 6.8 13.1 11 5.9 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CytochromB561_N PF09786.9 GAK68502.1 - 9.3 5.1 11.6 13 4.6 11.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal EXS PF03124.14 GAK68503.1 - 7.3e-74 249.0 22.7 1.2e-73 248.3 22.7 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAK68503.1 - 4.6e-55 188.1 1.1 5.8e-55 187.8 1.1 1.1 1 0 0 1 1 1 1 SPX domain ParE_toxin PF05016.15 GAK68503.1 - 0.028 15.0 0.5 0.45 11.2 0.3 2.8 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE Exo84_C PF16528.5 GAK68504.1 - 1.4e-48 165.5 0.9 2.3e-48 164.8 0.9 1.4 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 GAK68504.1 - 8.4e-18 64.2 0.2 2.5e-17 62.7 0.2 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 GAK68504.1 - 0.00099 19.2 1.3 0.0024 18.0 0.1 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 TetR_C_33 PF13305.6 GAK68504.1 - 0.29 11.9 0.0 0.29 11.9 0.0 3.2 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Bac_rhodopsin PF01036.18 GAK68506.1 - 1.3e-45 155.7 12.2 1.8e-45 155.3 12.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1304 PF06993.12 GAK68506.1 - 1.6 8.7 8.3 2.3 8.3 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) HEM4 PF02602.15 GAK68507.1 - 8.7e-17 61.2 0.1 5.7e-11 42.2 0.0 3.2 2 1 0 2 2 2 2 Uroporphyrinogen-III synthase HemD FAD_oxidored PF12831.7 GAK68508.1 - 0.22 10.8 0.8 0.31 10.3 0.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SNF2_N PF00176.23 GAK68512.1 - 2.2e-60 204.2 0.0 8.9e-60 202.2 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 GAK68512.1 - 4.1e-37 128.5 0.0 1.7e-36 126.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 GAK68512.1 - 4.5e-17 62.4 0.0 1.8e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 GAK68512.1 - 9.1e-05 22.4 13.5 0.0076 16.4 0.6 4.5 4 1 1 5 5 5 2 HEAT repeat UME PF08064.13 GAK68512.1 - 0.00024 21.0 1.4 0.2 11.6 0.1 4.3 5 0 0 5 5 5 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 GAK68512.1 - 0.011 16.3 0.1 0.057 14.0 0.0 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region ERCC3_RAD25_C PF16203.5 GAK68512.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3385 PF11865.8 GAK68512.1 - 0.095 12.6 0.4 0.24 11.3 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 GAK68512.1 - 0.81 10.3 9.7 21 5.8 0.3 4.9 5 0 0 5 5 5 0 HEAT-like repeat HHH PF00633.23 GAK68513.1 - 0.00022 20.9 0.1 0.00052 19.7 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Syntaxin PF00804.25 GAK68514.1 - 5e-33 114.5 11.7 8.4e-33 113.7 11.7 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAK68514.1 - 6.9e-10 38.8 1.0 6.9e-10 38.8 1.0 2.1 2 0 0 2 2 1 1 SNARE domain Syntaxin_2 PF14523.6 GAK68514.1 - 0.00041 20.7 21.7 0.00047 20.5 10.7 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Prominin PF05478.11 GAK68514.1 - 0.00094 17.3 10.2 0.0047 15.0 0.4 2.1 2 0 0 2 2 2 2 Prominin Allexi_40kDa PF05549.11 GAK68514.1 - 0.0038 16.8 5.0 0.007 15.9 1.0 2.1 2 0 0 2 2 2 1 Allexivirus 40kDa protein DUF2207 PF09972.9 GAK68514.1 - 0.012 14.4 2.8 0.014 14.1 0.0 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SKA1 PF07160.12 GAK68514.1 - 0.018 14.9 0.8 0.018 14.9 0.8 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 TB2_DP1_HVA22 PF03134.19 GAK68514.1 - 0.057 13.3 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family DUF2116 PF09889.9 GAK68514.1 - 0.07 13.1 0.4 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF5345 PF17280.2 GAK68514.1 - 0.078 13.0 1.5 0.32 11.0 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF3671 PF12420.8 GAK68514.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function FlaC_arch PF05377.11 GAK68514.1 - 0.12 12.8 3.2 5.3 7.5 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Dam1 PF08653.10 GAK68514.1 - 0.13 12.1 0.9 0.94 9.3 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Fungus-induced PF10917.8 GAK68514.1 - 0.18 12.2 0.6 0.34 11.2 0.6 1.4 1 0 0 1 1 1 0 Fungus-induced protein V_ATPase_I PF01496.19 GAK68514.1 - 0.22 9.4 11.9 0.012 13.6 3.9 1.9 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family PBP1_TM PF14812.6 GAK68514.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spectrin PF00435.21 GAK68514.1 - 0.59 10.7 10.8 0.53 10.8 0.1 3.0 3 1 0 3 3 2 0 Spectrin repeat DUF745 PF05335.13 GAK68514.1 - 0.63 9.7 17.6 0.09 12.5 4.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF745) TMCO5 PF14992.6 GAK68514.1 - 0.75 9.3 14.5 0.056 13.0 3.3 2.5 2 1 0 2 2 2 0 TMCO5 family DUF4094 PF13334.6 GAK68514.1 - 1.3 9.5 3.8 0.92 10.0 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) ISG65-75 PF11727.8 GAK68514.1 - 1.9 7.6 13.0 1.7 7.8 2.5 2.7 2 1 1 3 3 3 0 Invariant surface glycoprotein Synaptobrevin PF00957.21 GAK68514.1 - 2 8.3 12.4 0.54 10.1 3.4 2.8 2 1 0 2 2 2 0 Synaptobrevin VWA_2 PF13519.6 GAK68514.1 - 2.4 8.8 5.2 2.8 8.7 0.4 2.8 1 1 2 3 3 3 0 von Willebrand factor type A domain Tho2 PF11262.8 GAK68514.1 - 5.5 6.1 7.3 1.1 8.3 0.1 2.3 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 V-SNARE PF05008.15 GAK68514.1 - 8.6 6.8 18.1 0.29 11.5 1.5 3.9 3 2 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Mis12 PF05859.12 GAK68515.1 - 1.1e-26 93.5 0.0 1.8e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein NDUFV3 PF15880.5 GAK68515.1 - 0.079 13.0 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Annexin PF00191.20 GAK68515.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Annexin Proteasome PF00227.26 GAK68516.1 - 3.2e-28 98.5 0.0 4.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SAMP PF05924.11 GAK68516.1 - 0.026 13.8 0.7 0.047 13.0 0.7 1.4 1 0 0 1 1 1 0 SAMP Motif DUF2461 PF09365.10 GAK68517.1 - 5.5e-33 114.7 0.1 8e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) NAP PF00956.18 GAK68517.1 - 0.074 12.2 0.7 0.14 11.3 0.1 1.6 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Ribosomal_60s PF00428.19 GAK68517.1 - 2.4 8.8 10.1 1.4 9.6 3.6 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TAL_FSA PF00923.19 GAK68518.1 - 8.4e-94 314.1 0.3 1e-93 313.8 0.3 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pro_isomerase PF00160.21 GAK68518.1 - 3.9e-47 160.5 0.0 8.2e-47 159.4 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box PF00646.33 GAK68519.1 - 0.038 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 GAK68519.1 - 0.09 12.7 1.8 0.27 11.2 1.8 1.9 1 1 0 1 1 1 0 F-box-like TPR_2 PF07719.17 GAK68520.1 - 2.9e-27 92.6 17.5 0.00068 19.6 0.1 9.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAK68520.1 - 5.2e-23 79.9 1.8 0.00051 19.8 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAK68520.1 - 2.1e-20 72.7 15.5 1.4e-08 34.8 3.0 4.7 4 0 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAK68520.1 - 1.8e-12 46.4 0.1 0.016 15.4 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAK68520.1 - 3.3e-11 43.3 20.5 0.00012 22.3 0.1 7.3 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAK68520.1 - 2.2e-08 33.6 0.3 0.032 13.9 0.0 5.7 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 GAK68520.1 - 3.1e-07 30.6 35.3 0.046 14.5 0.2 9.0 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAK68520.1 - 4e-06 27.4 44.3 0.0002 21.9 1.7 8.1 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAK68520.1 - 1.5e-05 24.7 9.6 1.6 8.7 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAK68520.1 - 1.5e-05 25.0 27.2 0.051 13.7 0.4 6.7 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAK68520.1 - 2e-05 25.0 16.3 0.36 11.5 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAK68520.1 - 8.4e-05 22.7 0.2 13 6.5 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAK68520.1 - 9.5e-05 22.8 24.9 0.056 14.0 0.4 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAK68520.1 - 0.00018 21.1 0.8 0.0055 16.4 0.2 3.2 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 GAK68520.1 - 0.0021 17.9 14.3 0.99 9.6 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAK68520.1 - 0.054 13.2 6.6 2.1 8.0 0.7 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 GAK68520.1 - 7.2 6.8 10.8 78 3.5 0.0 5.0 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Diphthamide_syn PF01866.17 GAK68521.1 - 1.3e-64 218.6 0.0 3.6e-34 118.6 0.1 3.1 2 1 0 2 2 2 2 Putative diphthamide synthesis protein AAA_lid_6 PF17866.1 GAK68521.1 - 1.1 9.4 3.4 2.3 8.5 0.1 2.6 3 0 0 3 3 3 0 AAA lid domain hNIFK_binding PF12196.8 GAK68522.1 - 0.078 12.5 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Zn_clus PF00172.18 GAK68523.1 - 4.8e-09 36.2 12.5 8.2e-09 35.4 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_4 PF12146.8 GAK68528.1 - 9.9e-10 38.1 2.0 1.3e-07 31.2 2.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAK68528.1 - 1.2e-09 38.2 1.3 1.7e-07 31.2 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAK68528.1 - 6.8e-08 33.4 3.3 1e-07 32.8 3.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 GAK68528.1 - 2.6e-05 23.5 0.0 0.00012 21.3 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 GAK68528.1 - 0.00019 21.0 0.0 0.00053 19.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 GAK68528.1 - 0.022 13.7 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Peptidase_S15 PF02129.18 GAK68528.1 - 0.05 13.2 0.1 1.6 8.3 0.0 2.2 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Cupin_3 PF05899.12 GAK68529.1 - 6.8e-05 22.5 0.0 0.092 12.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GAK68529.1 - 0.00018 21.1 0.4 0.1 12.3 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_8 PF13621.6 GAK68529.1 - 0.031 14.0 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cupin_4 PF08007.12 GAK68529.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein PMI_typeI PF01238.21 GAK68529.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphomannose isomerase type I Cupin_1 PF00190.22 GAK68529.1 - 0.15 11.7 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Cupin HAD PF12710.7 GAK68532.1 - 1.1e-20 74.9 0.0 1.4e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 GAK68532.1 - 1.7e-09 37.6 0.0 5.4e-09 35.9 0.0 1.6 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 GAK68532.1 - 0.0002 20.9 0.2 0.0012 18.2 0.1 1.9 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 GAK68532.1 - 0.00021 21.7 0.6 0.0097 16.2 0.0 2.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.12 GAK68532.1 - 0.17 12.2 0.0 1.5 9.2 0.0 2.5 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Mem_trans PF03547.18 GAK68533.1 - 1.1e-33 116.2 2.6 3.3e-31 108.1 0.0 2.5 2 1 0 2 2 2 2 Membrane transport protein DUF4719 PF15843.5 GAK68533.1 - 2 8.5 4.3 7.8 6.6 4.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Gly-zipper_Omp PF13488.6 GAK68534.1 - 0.01 15.8 3.4 0.01 15.8 3.4 4.2 3 1 0 3 3 3 0 Glycine zipper Gly-zipper_YMGG PF13441.6 GAK68534.1 - 8.3 6.2 42.5 0.033 13.9 2.2 4.0 4 0 0 4 4 4 0 YMGG-like Gly-zipper Aft1_HRA PF11786.8 GAK68535.1 - 2.9e-27 94.8 10.9 2.9e-27 94.8 10.9 4.3 3 1 1 4 4 4 1 Aft1 HRA domain bZIP_1 PF00170.21 GAK68535.1 - 3.1e-10 40.0 7.6 6.3e-10 39.0 7.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAK68535.1 - 2.4e-06 27.5 8.6 8.4e-06 25.8 8.6 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAK68535.1 - 0.00096 19.6 5.5 0.0024 18.3 5.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor Aft1_OSA PF11785.8 GAK68535.1 - 0.00098 19.5 2.9 0.00098 19.5 2.9 4.8 4 1 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain Nnf1 PF03980.14 GAK68535.1 - 0.053 13.9 0.5 0.13 12.6 0.5 1.8 1 0 0 1 1 1 0 Nnf1 HALZ PF02183.18 GAK68535.1 - 0.12 12.7 0.6 0.24 11.7 0.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper SURF2 PF05477.11 GAK68535.1 - 2.3 7.9 14.0 3.9 7.1 8.3 2.6 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Pox_MCEL PF03291.16 GAK68537.1 - 2.1e-05 23.8 0.0 0.00012 21.3 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme RRM_1 PF00076.22 GAK68540.1 - 2.2e-58 194.0 0.0 1e-18 66.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAK68540.1 - 1.1e-05 25.1 0.0 0.0053 16.3 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAK68540.1 - 6.9e-05 22.8 0.0 1.8 8.6 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 GAK68540.1 - 0.00059 19.9 0.1 6.2 7.0 0.0 3.6 3 1 0 3 3 3 1 Limkain b1 RRM_occluded PF16842.5 GAK68540.1 - 0.0021 17.9 0.0 10 6.1 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif ATP-grasp_2 PF08442.10 GAK68540.1 - 0.0057 16.2 0.0 16 5.0 0.0 3.3 3 0 0 3 3 3 1 ATP-grasp domain RRM_Rrp7 PF17799.1 GAK68540.1 - 0.045 13.6 0.0 11 5.8 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain DUF3344 PF11824.8 GAK68540.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) bZIP_1 PF00170.21 GAK68541.1 - 4.4e-10 39.5 7.8 9.2e-10 38.5 7.7 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAK68541.1 - 2e-08 34.2 6.3 2.6e-08 33.8 5.7 1.5 1 1 0 1 1 1 1 Basic region leucine zipper RAC_head PF16717.5 GAK68541.1 - 0.0011 19.9 2.5 0.002 19.0 2.5 1.4 1 0 0 1 1 1 1 Ribosome-associated complex head domain Herpes_BLRF2 PF05812.12 GAK68541.1 - 0.0033 17.5 0.4 0.27 11.4 0.1 2.6 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein Spc7 PF08317.11 GAK68541.1 - 0.017 14.0 1.4 0.027 13.4 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 GAK68541.1 - 0.036 14.7 0.2 0.077 13.6 0.2 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Yuri_gagarin PF15934.5 GAK68541.1 - 0.068 13.0 1.7 0.11 12.4 1.7 1.2 1 0 0 1 1 1 0 Yuri gagarin Phlebovirus_NSM PF07246.11 GAK68541.1 - 0.069 12.5 2.7 0.11 11.9 2.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MIP-T3_C PF17749.1 GAK68541.1 - 0.098 12.6 5.3 2.7 7.9 0.1 2.4 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region PKcGMP_CC PF16808.5 GAK68541.1 - 0.11 12.4 0.7 0.26 11.2 0.7 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ZapB PF06005.12 GAK68541.1 - 0.11 13.0 1.5 0.27 11.7 1.5 1.6 1 0 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 GAK68541.1 - 0.11 12.9 0.4 0.11 12.9 0.4 1.7 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) bZIP_Maf PF03131.17 GAK68541.1 - 0.17 12.4 4.6 0.37 11.4 4.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 GAK68541.1 - 0.18 11.6 2.7 0.4 10.5 2.7 1.6 1 0 0 1 1 1 0 Septum formation initiator Ribosomal_S20p PF01649.18 GAK68541.1 - 1.8 9.2 6.8 2.9 8.6 3.8 2.3 1 1 1 2 2 2 0 Ribosomal protein S20 FAM76 PF16046.5 GAK68541.1 - 4.6 6.5 5.9 7.7 5.8 5.9 1.3 1 0 0 1 1 1 0 FAM76 protein PH PF00169.29 GAK68543.1 - 0.00042 20.8 0.3 2.4 8.7 0.1 3.3 3 0 0 3 3 3 2 PH domain PH_9 PF15410.6 GAK68543.1 - 0.007 16.7 0.0 0.13 12.6 0.0 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain DUF3292 PF11696.8 GAK68543.1 - 5.9 5.1 10.6 10 4.3 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Pkinase PF00069.25 GAK68544.1 - 1.8e-57 194.7 0.0 2.4e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68544.1 - 3.2e-28 98.7 0.0 4.5e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAK68544.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAK68544.1 - 0.031 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAK68544.1 - 0.043 13.4 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAK68544.1 - 0.046 13.6 0.3 2 8.3 0.3 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family PAT1 PF09770.9 GAK68545.1 - 5.3e-79 266.5 11.3 1.5e-77 261.7 11.3 2.5 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PDE4_UCR PF18100.1 GAK68545.1 - 0.084 13.5 0.4 0.52 11.0 0.0 2.5 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF3847 PF12958.7 GAK68545.1 - 8.4 6.6 7.6 2.8 8.1 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) G6PD_C PF02781.16 GAK68546.1 - 7.2e-110 366.7 0.0 1.2e-109 366.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAK68546.1 - 6.1e-60 202.9 0.1 1.1e-59 202.0 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 GAK68548.1 - 6.4e-09 36.7 3.5 1.1e-08 35.9 3.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAK68548.1 - 0.00015 21.1 0.0 0.00049 19.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAK68548.1 - 0.00015 21.5 0.1 1.1 8.8 0.0 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 GAK68548.1 - 0.00029 20.6 0.0 0.00075 19.2 0.0 1.6 2 0 0 2 2 2 1 Putative esterase YL1 PF05764.13 GAK68548.1 - 0.9 9.6 4.4 1.4 9.0 4.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Trypan_PARP PF05887.11 GAK68549.1 - 0.0011 18.9 9.5 0.0015 18.5 9.5 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 GAK68549.1 - 0.005 17.4 11.5 0.0054 17.3 11.5 1.1 1 0 0 1 1 1 1 TonB polyproline region Neisseria_TspB PF05616.13 GAK68549.1 - 3.1 6.2 19.4 3.3 6.1 19.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Aa_trans PF01490.18 GAK68550.1 - 1.8e-23 83.0 11.3 2.2e-23 82.7 11.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MMPL PF03176.15 GAK68550.1 - 0.038 12.9 3.8 0.062 12.2 3.8 1.2 1 0 0 1 1 1 0 MMPL family Glyco_hydro_15 PF00723.21 GAK68551.1 - 2.5e-81 273.7 1.7 3.7e-81 273.2 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF1921 PF09081.10 GAK68551.1 - 0.01 16.1 0.2 0.039 14.2 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1921) FA_hydroxylase PF04116.13 GAK68552.1 - 1.6e-20 73.8 9.4 1.6e-20 73.8 9.4 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sod_Fe_C PF02777.18 GAK68553.1 - 1.3e-34 118.4 0.4 2.3e-34 117.6 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAK68553.1 - 2.3e-31 108.1 5.6 2.3e-31 108.1 3.4 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CAS_C PF12026.8 GAK68553.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain N2227 PF07942.12 GAK68554.1 - 2.2e-83 279.6 0.0 2.4e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Rot1 PF10681.9 GAK68557.1 - 8.6e-58 195.3 3.1 9.1e-58 195.2 1.7 1.6 2 0 0 2 2 2 1 Chaperone for protein-folding within the ER, fungal Acyl-CoA_dh_M PF02770.19 GAK68558.1 - 8.1e-20 70.8 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 GAK68558.1 - 2.7e-10 40.9 0.1 9.5e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 GAK68558.1 - 4.3e-08 33.5 2.5 3.2e-07 30.7 2.5 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3243 PF11588.8 GAK68559.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) TAL_FSA PF00923.19 GAK68561.1 - 7e-28 97.8 0.0 1.1e-27 97.2 0.0 1.4 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 GAK68562.1 - 8.3e-37 127.0 0.0 1.5e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAK68562.1 - 6.2e-23 81.4 0.0 1.1e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAK68562.1 - 0.052 13.5 0.2 4.2 7.2 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Topoisom_I_N PF02919.15 GAK68562.1 - 0.21 11.1 0.2 0.49 9.9 0.1 1.5 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment TFIIA PF03153.13 GAK68562.1 - 0.68 9.9 9.0 0.09 12.8 3.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit E_Pc_C PF06752.12 GAK68562.1 - 0.98 9.5 9.2 0.13 12.3 4.8 1.8 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus AKAP2_C PF15304.6 GAK68562.1 - 1.3 8.3 7.5 0.1 11.9 1.8 1.9 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Spt20 PF12090.8 GAK68562.1 - 1.3 8.6 11.4 2.8 7.5 11.4 1.5 1 0 0 1 1 1 0 Spt20 family Aa_trans PF01490.18 GAK68563.1 - 0.00097 17.9 9.8 0.0013 17.5 9.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MASE5 PF17178.4 GAK68563.1 - 3.3 7.5 8.9 0.12 12.2 0.8 2.2 1 1 0 2 2 2 0 Membrane-associated sensor Glyco_hydro_43 PF04616.14 GAK68564.1 - 5.9e-08 32.4 0.0 7.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1387 PF07139.11 GAK68565.1 - 1.4 8.6 6.0 1.8 8.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Histone PF00125.24 GAK68566.1 - 4.7e-51 172.6 2.5 5.2e-51 172.4 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAK68566.1 - 1e-05 25.8 0.0 1.6e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAK68566.1 - 6.5e-05 23.0 0.5 9.9e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 GAK68566.1 - 0.00045 20.8 1.6 0.00055 20.5 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 GAK68566.1 - 0.0019 18.5 0.1 0.0036 17.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 GAK68566.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 GAK68566.1 - 0.074 13.1 0.2 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ribosomal_S15 PF00312.22 GAK68567.1 - 5.2e-25 87.5 0.4 1e-24 86.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 RNA_pol_Rpb1_7 PF04990.12 GAK68567.1 - 0.12 12.4 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 HTH_Tnp_1 PF01527.20 GAK68568.1 - 1.1e-22 80.2 0.1 1.3e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 GAK68568.1 - 1.2e-06 28.5 0.1 2.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 GAK68568.1 - 4e-05 23.3 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 GAK68568.1 - 0.00022 21.2 0.0 0.00041 20.3 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 GAK68568.1 - 0.013 15.6 0.3 0.026 14.7 0.3 1.6 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_11 PF08279.12 GAK68568.1 - 0.094 12.7 0.0 0.38 10.7 0.0 1.9 2 1 0 2 2 2 0 HTH domain ICL PF00463.21 GAK68569.1 - 1.4e-158 528.7 0.0 1.6e-158 528.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAK68569.1 - 1.6e-09 37.6 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 GAK68569.1 - 0.055 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain NUDIX_4 PF14815.6 GAK68570.1 - 2e-19 69.6 0.1 3.9e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain Whib PF02467.16 GAK68570.1 - 0.011 16.3 3.0 0.3 11.7 1.1 2.8 2 0 0 2 2 2 0 Transcription factor WhiB EndIII_4Fe-2S PF10576.9 GAK68570.1 - 0.016 15.5 8.9 0.016 15.5 8.9 2.2 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III NUDE_C PF04880.13 GAK68570.1 - 0.09 13.2 4.4 1.6 9.2 0.2 3.1 2 1 1 3 3 3 0 NUDE protein, C-terminal conserved region Pox_Ag35 PF03286.14 GAK68572.1 - 0.0042 16.9 2.9 0.0068 16.2 2.9 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 GAK68572.1 - 0.0074 16.0 5.6 0.0091 15.8 5.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GAK68572.1 - 0.016 14.6 5.5 0.015 14.6 5.5 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GAK68572.1 - 0.18 11.4 2.5 0.18 11.3 2.5 1.1 1 0 0 1 1 1 0 PPP4R2 EXS PF03124.14 GAK68572.1 - 0.41 9.9 0.8 0.49 9.7 0.8 1.1 1 0 0 1 1 1 0 EXS family FAM176 PF14851.6 GAK68572.1 - 0.62 9.7 2.2 1.2 8.8 2.2 1.4 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.12 GAK68572.1 - 0.62 8.8 4.9 0.71 8.6 4.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nucleo_P87 PF07267.11 GAK68572.1 - 0.69 8.7 1.9 0.78 8.5 1.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 GAK68572.1 - 1.2 8.4 8.0 1.6 8.0 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.8 GAK68572.1 - 1.3 10.1 12.4 0.16 13.0 6.7 2.2 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 GAK68572.1 - 2 6.6 4.3 2.5 6.3 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 GAK68572.1 - 9.3 6.7 14.4 9.1 6.7 13.1 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Moesziomyces_antarcticus-ASM74776v1/GCA_000747765.1_ASM74776v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Moesziomyces_antarcticus-ASM74776v1/GCA_000747765.1_ASM74776v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Moesziomyces_antarcticus-ASM74776v1/GCA_000747765.1_ASM74776v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Moesziomyces_antarcticus-ASM74776v1/GCA_000747765.1_ASM74776v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 01:02:58 2019 # [ok]